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Organoids identify a role for IL-7 in coeliac disease

Nature
Reporting in Nature, Santos et al. have used human organoids generated from individuals with coeliac disease to identify an unexpected role...
1 month ago

Wheat Fermentation With Enterococcus mundtii QAUSD01 and Wickerhamomyces anomalus QAUWA03 Consortia Induces Concurrent Gliadin and Phytic Acid Degradation and Inhibits Gliadin Toxicity in Caco-2 Monolayers

Frontiers
Foods containing high amounts of either phytic acid or gliadin can pose a risk for development of iron deficiency and celiac disease, respectively.
8 months ago

The Impact of the 33-mer Gluten-Derived Peptide on Celiac Disease

Celiac.com
This study explores the formation of DGP oligomers and their effect on gut permeability, shedding light on potential mechanisms behind the development of...
4 months ago

Bromelain-loaded nanocomposites decrease inflammatory and cytotoxicity effects of gliadin on Caco-2 cells and peripheral blood mononuclear cells of celiac patients | Scientific Reports

Nature
Here, we developed Bromelain-Loaded Nanocomposites (BLNCs) to improve the stability and retention of bromelain enzyme activity.
10 months ago

RNAi silencing of wheat gliadins alters the network of transcription factors that regulate the synthesis of seed storage proteins toward maintaining grain protein levels

Frontiers
RNAi silencing of wheat gliadins alters the network of transcription factors that regulate the synthesis of seed storage proteins toward maintaining grain...
8 months ago

Celiac disease: New findings on the effects of gluten

Universität Bielefeld
The study team has now discovered that the presence of DGP oligomers may open the tightly closed gut lining, leading to the leaky gut syndrome.
4 months ago

Nanoparticles containing gliadin could allow celiac disease patients to eat a normal diet

News-Medical
In a collaborative project led by Dr. Tobias Freitag working in Professor Seppo Meri's research group in the Translational Immunology Research...
55 months ago

Characterization of gliadin, secalin and hordein fractions using analytical techniques

Nature
Prolamins, alcohol soluble storage proteins of the Triticeae tribe of Gramineae family, are known as gliadin, secalin and hordein in wheat,...
34 months ago

The protective role of Lactobacillus rhamnosus GG postbiotic on the alteration of autophagy and inflammation pathways induced by gliadin in intestinal models

Frontiers
Celiac disease (CD) is an autoimmune enteropathy caused by an abnormal immune response to gliadin peptides in genetically predisposed...
17 months ago

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

Nature
Gliadin reactive T cells involved in CeD pathogenesis cross-react with ubiquitous bacterial peptides, thereby suggesting microbial exposure as a potential...
57 months ago