WO2006050225A3 - Apparatus and methods for performing brain surgery - Google Patents
Apparatus and methods for performing brain surgery Download PDFInfo
- Publication number
- WO2006050225A3 WO2006050225A3 PCT/US2005/039185 US2005039185W WO2006050225A3 WO 2006050225 A3 WO2006050225 A3 WO 2006050225A3 US 2005039185 W US2005039185 W US 2005039185W WO 2006050225 A3 WO2006050225 A3 WO 2006050225A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- obturator
- cannula
- surgery
- methods
- target tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3415—Trocars; Puncturing needles for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
- A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
- A61M29/02—Dilators made of swellable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
- A61B17/3431—Cannulas being collapsible, e.g. made of thin flexible material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
- A61B17/3439—Cannulas with means for changing the inner diameter of the cannula, e.g. expandable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00902—Material properties transparent or translucent
- A61B2017/00907—Material properties transparent or translucent for light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
- A61B17/3421—Cannulas
- A61B2017/3445—Cannulas used as instrument channel for multiple instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2051—Electromagnetic tracking systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2055—Optical tracking systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B2090/364—Correlation of different images or relation of image positions in respect to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3937—Visible markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/397—Markers, e.g. radio-opaque or breast lesions markers electromagnetic other than visible, e.g. microwave
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3983—Reference marker arrangements for use with image guided surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M2025/0024—Expandable catheters or sheaths
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/665,666 US20080109026A1 (en) | 2004-10-28 | 2005-10-28 | Apparatus and Methods for Performing Brain Surgery |
US13/280,015 US9770261B2 (en) | 2004-10-28 | 2011-10-24 | Surgical access assembly and method of using same |
US13/444,713 US9186175B2 (en) | 2004-10-28 | 2012-04-11 | Surgical access assembly and method of using same |
US13/474,433 US20120289816A1 (en) | 2004-10-28 | 2012-05-17 | Surgical access assembly and method of using same |
US13/786,062 US9387010B2 (en) | 2004-10-28 | 2013-03-05 | Surgical access assembly and method of using same |
US13/786,186 US9161820B2 (en) | 2004-10-28 | 2013-03-05 | Surgical access assembly and method of using same |
US14/847,863 US10143366B2 (en) | 2004-10-28 | 2015-09-08 | Surgical access assembly and method of using same |
US14/877,438 US9622777B2 (en) | 2004-10-28 | 2015-10-07 | Surgical access assembly and method of using same |
US16/102,416 US11464539B2 (en) | 2004-10-28 | 2018-08-13 | Surgical access assembly and method of using same |
US16/208,085 US11412923B2 (en) | 2004-10-28 | 2018-12-03 | Surgical access assembly and method of using same |
US17/115,472 US11864793B2 (en) | 2004-10-28 | 2020-12-08 | Surgical access assembly and method of using same |
US17/220,983 US20210236161A1 (en) | 2004-10-28 | 2021-04-02 | Surgical access assembly and method of using same |
US17/888,196 US20230045431A1 (en) | 2004-10-28 | 2022-08-15 | Surgical access assembly and method of using same |
US18/528,121 US20240099740A1 (en) | 2004-10-28 | 2023-12-04 | Surgical access assembly and method of using same |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62299104P | 2004-10-28 | 2004-10-28 | |
US62309404P | 2004-10-28 | 2004-10-28 | |
US60/623,094 | 2004-10-28 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US13/444,722 Continuation-In-Part US9579121B2 (en) | 2004-10-28 | 2012-04-11 | Holding arrangement for a surgical access system |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/665,666 A-371-Of-International US20080109026A1 (en) | 2004-10-28 | 2005-10-28 | Apparatus and Methods for Performing Brain Surgery |
US13/280,015 Continuation-In-Part US9770261B2 (en) | 2004-10-28 | 2011-10-24 | Surgical access assembly and method of using same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006050225A2 WO2006050225A2 (en) | 2006-05-11 |
WO2006050225A3 true WO2006050225A3 (en) | 2006-09-08 |
Family
ID=39227003
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/038828 WO2006050047A2 (en) | 2004-10-28 | 2005-10-28 | Apparatus and methods for performing brain surgery |
PCT/US2005/039185 WO2006050225A2 (en) | 2004-10-28 | 2005-10-28 | Apparatus and methods for performing brain surgery |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/038828 WO2006050047A2 (en) | 2004-10-28 | 2005-10-28 | Apparatus and methods for performing brain surgery |
Country Status (1)
Country | Link |
---|---|
WO (2) | WO2006050047A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9216015B2 (en) | 2004-10-28 | 2015-12-22 | Vycor Medical, Inc. | Apparatus and methods for performing brain surgery |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9387010B2 (en) | 2004-10-28 | 2016-07-12 | Nico Corporation | Surgical access assembly and method of using same |
US9265523B2 (en) | 2011-10-24 | 2016-02-23 | Nico Corporation | Surgical access system with navigation element and method of using same |
US9186175B2 (en) | 2004-10-28 | 2015-11-17 | Nico Corporation | Surgical access assembly and method of using same |
US9161820B2 (en) | 2004-10-28 | 2015-10-20 | Nico Corporation | Surgical access assembly and method of using same |
US9770261B2 (en) | 2004-10-28 | 2017-09-26 | Nico Corporation | Surgical access assembly and method of using same |
US20060287583A1 (en) | 2005-06-17 | 2006-12-21 | Pool Cover Corporation | Surgical access instruments for use with delicate tissues |
JP5496677B2 (en) * | 2006-11-27 | 2014-05-21 | ヴァイコール メディカル エルエルシー | Surgical access device for sensitive tissue |
US20080183074A1 (en) * | 2007-01-25 | 2008-07-31 | Warsaw Orthopedic, Inc. | Method and apparatus for coordinated display of anatomical and neuromonitoring information |
MY149480A (en) | 2009-03-26 | 2013-08-30 | Univ Malaya | An apparatus for surgery |
DE102009029904A1 (en) * | 2009-06-19 | 2010-12-23 | Olympus Winter & Ibe Gmbh | Laparoscopic port with tube piece |
DE102011107615A1 (en) * | 2011-06-30 | 2013-01-03 | Siegfried Riek | trocar |
DE102012203908B3 (en) | 2012-03-13 | 2013-06-06 | Siegfried Riek | Instrument system for minimally invasive surgery in the single-port technique |
US9757147B2 (en) | 2012-04-11 | 2017-09-12 | Nico Corporation | Surgical access system with navigation element and method of using same |
US10166017B2 (en) * | 2013-08-05 | 2019-01-01 | Cook Medical Technologies Llc | Medical devices having a releasable tubular member and methods of using the same |
WO2015175635A1 (en) | 2014-05-13 | 2015-11-19 | Vycor Medical, Inc. | Guidance system mounts for surgical introducers |
GB201411486D0 (en) * | 2014-06-27 | 2014-08-13 | Isis Innovation | Apparatus for providing and maintaining access to a surgical site |
US20170215860A1 (en) * | 2014-07-23 | 2017-08-03 | Robert TRIMARCHE | Modifications to access ports for minimally invasive neuro surgery |
US10456061B2 (en) | 2014-11-12 | 2019-10-29 | Nico Corporation | Holding arrangement for a surgical access system |
CN104771222B (en) * | 2015-03-17 | 2017-08-25 | 绍兴第二医院 | A kind of preparation method of nerve endoscope sheath and the nerve endoscope sheath |
CN105343995A (en) * | 2015-11-16 | 2016-02-24 | 深圳市擎源医疗器械有限公司 | Brain retracting apparatus |
US10765450B2 (en) | 2016-03-15 | 2020-09-08 | Nico Corporation | Selectively lockable holding arrangement for a surgical access system |
US11413066B2 (en) | 2016-03-15 | 2022-08-16 | Nico Corporation | Selectively lockable holding arrangement for a surgical access system |
US10543057B2 (en) | 2016-03-15 | 2020-01-28 | Nico Corporation | Selectively lockable holding arrangement for a surgical access system |
WO2017201203A1 (en) | 2016-05-17 | 2017-11-23 | Rebound Therapeutics Corporation | Methods and devices for color detection to localize the blood mass of an intracerebral hematoma |
US10543016B2 (en) | 2016-11-07 | 2020-01-28 | Vycor Medical, Inc. | Surgical introducer with guidance system receptacle |
US10376258B2 (en) | 2016-11-07 | 2019-08-13 | Vycor Medical, Inc. | Surgical introducer with guidance system receptacle |
DE102018216760A1 (en) | 2018-09-28 | 2020-04-02 | Carl Zeiss Meditec Ag | Applicator for intraoperative radiation therapy |
Citations (19)
Publication number | Priority date | Publication date | Assignee | Title |
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US3690323A (en) * | 1970-12-01 | 1972-09-12 | Us Army | Device for draining ventricular fluid in cases of hydrocephalus |
US4638798A (en) * | 1980-09-10 | 1987-01-27 | Shelden C Hunter | Stereotactic method and apparatus for locating and treating or removing lesions |
US5183464A (en) * | 1991-05-17 | 1993-02-02 | Interventional Thermodynamics, Inc. | Radially expandable dilator |
US5320611A (en) * | 1993-02-04 | 1994-06-14 | Peter M. Bonutti | Expandable cannula having longitudinal wire and method of use |
US5431676A (en) * | 1993-03-05 | 1995-07-11 | Innerdyne Medical, Inc. | Trocar system having expandable port |
US5860996A (en) * | 1994-05-26 | 1999-01-19 | United States Surgical Corporation | Optical trocar |
US6047218A (en) * | 1996-10-28 | 2000-04-04 | Ep Technologies, Inc. | Systems and methods for visualizing interior tissue regions |
US6129685A (en) * | 1994-02-09 | 2000-10-10 | The University Of Iowa Research Foundation | Stereotactic hypothalamic obesity probe |
US6293952B1 (en) * | 1997-07-31 | 2001-09-25 | Circon Corporation | Medical instrument system for piercing through tissue |
US6331180B1 (en) * | 1988-05-03 | 2001-12-18 | Sherwood Services Ag | Target-centered stereotaxtic surgical arc system with reorientatable arc axis |
US6374135B1 (en) * | 1990-10-19 | 2002-04-16 | Saint Louis University | System for indicating the position of a surgical probe within a head on an image of the head |
US6416520B1 (en) * | 1999-04-23 | 2002-07-09 | Sherwood Services Ag | Microdrive for probes |
US20030073934A1 (en) * | 2001-10-17 | 2003-04-17 | David A. Putz | Double slotted-cannula device and method of use |
US6669685B1 (en) * | 1997-11-06 | 2003-12-30 | Biolase Technology, Inc. | Tissue remover and method |
US20040024291A1 (en) * | 2002-08-01 | 2004-02-05 | Zinkel John L. | Method and apparatus for spinal surgery |
US20040059375A1 (en) * | 2000-10-06 | 2004-03-25 | Integrated Vascular Systems, Inc. | Apparatus and methods for positioning a vascular sheath |
US20040068172A1 (en) * | 1996-02-27 | 2004-04-08 | Kent Ridge Digital Labs | Curved surgical instruments and method of mapping a curved path for stereotactic surgery |
US20040102804A1 (en) * | 1999-08-10 | 2004-05-27 | Chin Albert K. | Apparatus and methods for endoscopic surgical procedures |
US6942634B2 (en) * | 2002-03-22 | 2005-09-13 | Twin Star Medical, Inc. | System for treating tissue swelling |
-
2005
- 2005-10-28 WO PCT/US2005/038828 patent/WO2006050047A2/en active Application Filing
- 2005-10-28 WO PCT/US2005/039185 patent/WO2006050225A2/en active Application Filing
Patent Citations (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3690323A (en) * | 1970-12-01 | 1972-09-12 | Us Army | Device for draining ventricular fluid in cases of hydrocephalus |
US4638798A (en) * | 1980-09-10 | 1987-01-27 | Shelden C Hunter | Stereotactic method and apparatus for locating and treating or removing lesions |
US6331180B1 (en) * | 1988-05-03 | 2001-12-18 | Sherwood Services Ag | Target-centered stereotaxtic surgical arc system with reorientatable arc axis |
US6374135B1 (en) * | 1990-10-19 | 2002-04-16 | Saint Louis University | System for indicating the position of a surgical probe within a head on an image of the head |
US5183464A (en) * | 1991-05-17 | 1993-02-02 | Interventional Thermodynamics, Inc. | Radially expandable dilator |
US5320611A (en) * | 1993-02-04 | 1994-06-14 | Peter M. Bonutti | Expandable cannula having longitudinal wire and method of use |
US5431676A (en) * | 1993-03-05 | 1995-07-11 | Innerdyne Medical, Inc. | Trocar system having expandable port |
US6129685A (en) * | 1994-02-09 | 2000-10-10 | The University Of Iowa Research Foundation | Stereotactic hypothalamic obesity probe |
US5860996A (en) * | 1994-05-26 | 1999-01-19 | United States Surgical Corporation | Optical trocar |
US20040068172A1 (en) * | 1996-02-27 | 2004-04-08 | Kent Ridge Digital Labs | Curved surgical instruments and method of mapping a curved path for stereotactic surgery |
US6047218A (en) * | 1996-10-28 | 2000-04-04 | Ep Technologies, Inc. | Systems and methods for visualizing interior tissue regions |
US6293952B1 (en) * | 1997-07-31 | 2001-09-25 | Circon Corporation | Medical instrument system for piercing through tissue |
US6669685B1 (en) * | 1997-11-06 | 2003-12-30 | Biolase Technology, Inc. | Tissue remover and method |
US6416520B1 (en) * | 1999-04-23 | 2002-07-09 | Sherwood Services Ag | Microdrive for probes |
US20040102804A1 (en) * | 1999-08-10 | 2004-05-27 | Chin Albert K. | Apparatus and methods for endoscopic surgical procedures |
US20040059375A1 (en) * | 2000-10-06 | 2004-03-25 | Integrated Vascular Systems, Inc. | Apparatus and methods for positioning a vascular sheath |
US20030073934A1 (en) * | 2001-10-17 | 2003-04-17 | David A. Putz | Double slotted-cannula device and method of use |
US6942634B2 (en) * | 2002-03-22 | 2005-09-13 | Twin Star Medical, Inc. | System for treating tissue swelling |
US20040024291A1 (en) * | 2002-08-01 | 2004-02-05 | Zinkel John L. | Method and apparatus for spinal surgery |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9216015B2 (en) | 2004-10-28 | 2015-12-22 | Vycor Medical, Inc. | Apparatus and methods for performing brain surgery |
US9386974B2 (en) | 2004-10-28 | 2016-07-12 | Vycor Medical, Inc. | Apparatus and methods for performing brain surgery |
Also Published As
Publication number | Publication date |
---|---|
WO2006050047A2 (en) | 2006-05-11 |
WO2006050047A3 (en) | 2006-08-24 |
WO2006050225A2 (en) | 2006-05-11 |
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