CN103353992A - Film mark-point-free automatic positioning method - Google Patents

Film mark-point-free automatic positioning method Download PDF

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Publication number
CN103353992A
CN103353992A CN2013103066523A CN201310306652A CN103353992A CN 103353992 A CN103353992 A CN 103353992A CN 2013103066523 A CN2013103066523 A CN 2013103066523A CN 201310306652 A CN201310306652 A CN 201310306652A CN 103353992 A CN103353992 A CN 103353992A
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data
film
rotation
anglec
planning data
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CN103353992B (en
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张可
戴建荣
张中柱
王惠清
闫秀芬
谢玲灵
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Beijing Zhongkanglian Medical Equipment Dev Co Ltd
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Beijing Zhongkanglian Medical Equipment Dev Co Ltd
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Abstract

The invention discloses a film mark-point-free automatic positioning method. The method comprises the following steps: loading film dosage data and plan data corresponding to the film dosage data; obtaining data having the same pixel dimension as the plan data through interpolation; selecting a focus area; searching for an optimum coupling area of the focus area in the plan data through translation and rotation operation and obtaining a translation parameter and a rotation angle; and performing, according to the translation parameter, the rotation angle and the zoom information of the interpolation, directional operation on the film dosage data and obtaining data coupling to the plan data. By using the method provided by the invention, errors caused by manual operation in a registering process can be effectively prevented.

Description

Unmarked some automatic positioning method of a kind of film
Technical field
The present invention relates to the unmarked independent positioning method of a kind of film, relate in particular to a kind of being used in the strength regulated shape-adapted radiation therapeutic, film is carried out the automatically method of location of unmarked point, belong to the Medical Imaging Technology field.
Background technology
Radiation therapy, chemotherapy and operation are three large technological means for the treatment of tumour.Develop rapidly along with computer technology and iconography, huge change has appearred in radiation therapy, from 20 century 70s two-dimentional traditional radiation therapy, the 3 dimensional conformal radiation therapy of the eighties in 20th century (3dimensional conformal radiation therapy before, be called for short 3D-CRT), to strength regulated shape-adapted radiation therapeutic (the intensity modulated radiation therapy that rose in recent years, be called for short IMRT), the epoch that radiation therapy is extensive from dosage control, dosage distributes to be blured enter into the epoch of precise radiotherapy.
In the strength regulated shape-adapted radiation therapeutic process, because intermediate link is more, its dosage accuracy is subject to the several factors impact.In strength regulated shape-adapted radiation therapeutic, the radiological dose that high gradient changes accurately is implemented in it the patient, and the dosage verifying before the treatment becomes the important step of quality assurance and dosage control.Film dosimetry checking is obtained image convenient because its spatial resolution is high, is beneficial to long preservation, and has the high advantages such as cost performance and be widely used in the dosage verifying of strength regulated shape-adapted radiation therapeutic.
The key step of film dosimetry checking comprises exposure sufferer treatment sheet, and exposure calibration sheet is by exposure sequential scanning film.Wherein, the treatment of exposure sufferer refers to that with sheet film is placed on the center exposure for the treatment of launched field and carries out mark (being used for recording image in analysis subsequently) with reference point, being about to film is positioned in the solid water phantom, token-based on schedule, shut phantom, according to schedule in suitable degree of depth irradiation.This shows, carry out mark (location), is the committed step that improves film dosimetry checking accuracy.
At present, film locator meams commonly used comprises: 1. metal dots is squeezed on the film; 2. prick the hole with metal needle at film, draw mark with marker pen at film.In above-mentioned the 1st kind of mode, metal dots is squeezed in and forms pseudo-shadow on the film, and this puppet shadow can produce Rapid Dose Calculation in the die body and disturb.In above-mentioned the 2nd kind of mode, although in hole that film is pricked and the marker pen vestige on the film Rapid Dose Calculation is not exerted an influence, but because the difference of manually-operated gimmick can produce error, the film displacement all may occur to pre-irradiation in these two kinds of locator meamss after film is put mark in addition, produce site error, thereby cause analyzing the serious distortion of data.
In application number was 200410049990.4 Chinese invention patent application, the film localization method in a kind of radiotherapy dosage checking was disclosed.The method is by carrying out in advance mark on film, and this mark is mapped with transferring the mark on the strong authentication die body, solved film and transfer the dose distribution map location of strong authentication die body inaccurate, the bad drawback of effect.This technical scheme need not to use highdensity metal pilot pin, can accurately locate any tomography of accent strong authentication die body and the position of film, and accurately position rotating is transferred the strong authentication die body.
Summary of the invention
Technical matters to be solved by this invention is to provide a kind of film unmarked some automatic positioning method.The method is not introduced the pseudo-shadow of metal dots and is disturbed, and not be used in yet and carries out the handmarking in the process of putting, and has effectively avoided in the registration process because the error that manual operation is introduced.
For realizing above-mentioned goal of the invention, the present invention adopts following technical scheme:
Unmarked some automatic positioning method of a kind of film comprises the steps:
Be written into the film dosimetry data and with the planning data of the corresponding aspect of film dosimetry data;
Obtain data with planning data same pixel size by interpolation;
Choose region-of-interest;
In planning data, seek the optimum matching zone of region-of-interest by translation, rotary manipulation, obtain translation parameters and the anglec of rotation;
According to the scalability information of translation parameters, the anglec of rotation and interpolation, the film dosimetry data travel direction operation to original obtains the data that are complementary with planning data.
Wherein more preferably, the step that obtains translation parameters and the anglec of rotation further comprises:
With the region-of-interest chosen as search pattern, in planning data from top to bottom, travel through from left to right;
At each traversal point, template is done rotation process;
Under each anglec of rotation, from planning data, choose the zone consistent with postrotational template size, calculate related coefficient, obtain the related coefficient array;
In the related coefficient array, choose the related coefficient maximal value;
Obtain translation parameters and the anglec of rotation from the corresponding traversal point of related coefficient maximal value and the anglec of rotation.
Wherein more preferably, obtain the optimum matching zone of region-of-interest in the planning data by the related coefficient maximal value.
Wherein more preferably, the step that obtains the data that are complementary with planning data further comprises:
Utilize translation parameters and the anglec of rotation that the film dosimetry data are done inverse operation, travel direction is proofreaied and correct;
The Pixel Dimensions ratio of film dosimetry data changes oppositely adjustment during according to interpolation, finally determines film dosimetry data and planning data to be complementary the film dosimetry data data center position corresponding with planning data in terms of content.
Unmarked some automatic positioning method of film provided by the present invention at first introduced the film dosimetry data, from dose matrix, select again the dosage plane of corresponding space position, adopt the rigid image registration technology with two width of cloth images automatically be rotated, translation to be reaching the optimal registration effect, thereby avoided in the registration process because the error that manual operation is introduced.
Description of drawings
Fig. 1 is the overall flow schematic diagram of unmarked some automatic positioning method of film provided by the present invention;
Fig. 2 is the exemplary plot that the original film dose data is written into analysis window;
Fig. 3 is the exemplary plot that planning data is written into analysis window;
Fig. 4 is the exemplary plot that the film dosimetry data behind the location are written into analysis window;
Fig. 5 is the exemplary plot that the zone that is complementary with the film region-of-interest in the planning data is written into analysis window.
Embodiment
Below in conjunction with the drawings and specific embodiments technical scheme of the present invention is elaborated.
As shown in Figure 1, the invention provides unmarked some automatic positioning method of a kind of film, comprise the steps: to be written into the film dosimetry data and with the planning data of the corresponding aspect of film dosimetry data; Obtain data with planning data same pixel size by interpolation; Choose region-of-interest; In planning data, seek the optimum matching zone of region-of-interest by translation, rotary manipulation, obtain translation parameters and the anglec of rotation; According to the scalability information of translation parameters, the anglec of rotation and interpolation, the film dosimetry data travel direction operation to original obtains the data that are complementary with planning data.The below launches detailed specific description to this.
At first, introduce be written into the film dosimetry data and with the step of the planning data of the corresponding aspect of film dosimetry data.
As shown in Figure 2, the gradation data after the scanning is calibrated to corresponding original film dose data by corresponding calibration curve, is loaded into analysis window.As shown in Figure 3, at TPS(Treatment Planning System, radiotherapy treatment planning system) planning data in the planning data of same depth aspect when finding with the actual irradiation of film, be written in the analysis window.
Secondly, introduce by interpolation and obtain step with the data of planning data same pixel size.
Because the Pixel Dimensions of film dosimetry data and the Pixel Dimensions of planning data are inconsistent, the two need to the Pixel Dimensions of film dosimetry data be adjusted into consistent data with the Pixel Dimensions of planning data by operations such as interpolation, so that can analyze comparison at same size.After adjusting, be written in the analysis window.
Again, introduce the step of choosing region-of-interest.
As shown in Figure 4, manually in the film dosimetry data, haul out a rectangle or border circular areas.This zone should be able to comprise the main part of exposure dose, and the border that produces when avoiding film scanning simultaneously obtains region-of-interest (Region Of Interest is called for short ROI), and it is loaded in the analysis window.
Again, introduce the optimum matching zone of in planning data, seeking region-of-interest by translation, rotary manipulation, obtain the step of translation parameters and the anglec of rotation.
The present invention adopts the rigid image registration technology that planning data and region-of-interest are carried out registration process, obtains the optimum matching zone.Be described as follows: the region-of-interest chosen as search pattern, is carried out traversing operation from top to bottom, from left to right in planning data.At each traversal point, template is done 360 degree rotations.Under each anglec of rotation, choose the zone consistent with postrotational template size from planning data, calculate related coefficient, obtain the related coefficient array.In this related coefficient array, choose maximal value, from the corresponding traversal point of this maximal value and the anglec of rotation, can obtain translation parameters and the anglec of rotation.By this related coefficient maximal value corresponding translation parameters and the anglec of rotation, obtain the optimum matching zone of region-of-interest in the planning data.Be loaded in the analysis window.In the embodiment shown in fig. 5, planning data has been rotated 180.02 degree, and is corresponding with the corresponding point at planning data center, obtains the optimum matching zone of region-of-interest in the planning data.
At last, introduce the scalability information according to translation parameters, the anglec of rotation and interpolation, to original film dosimetry data travel direction operation, obtain the step of the data that are complementary with planning data.
In this step, according to translation parameters and the anglec of rotation film dosimetry data are done inverse operation, travel direction is proofreaied and correct; Again according to before during interpolation operation the Pixel Dimensions ratio of film dosimetry data change and oppositely adjust, finally determine the film dosimetry data data center position corresponding with planning data, so that film dosimetry data and planning data are complementary in terms of content, it is loaded in the analysis window.
In sum, in unmarked some automatic positioning method of film provided by the invention, at first the film dosimetry data are introduced, from dose matrix, select again the dosage plane of corresponding space position, adopt the rigid image registration technology with two width of cloth images automatically be rotated, translation to be to reach the optimal registration effect.Like this, in die body, do not introduce the pseudo-shadow of metal dots and disturb, not be used in yet and carry out the handmarking in the process of putting, effectively avoided in the registration process because the error that manual operation is introduced.Utilize the present invention, the troublesome operation in the time of can also reducing registration has further improved work efficiency.
The above has been described in detail unmarked some automatic positioning method of film provided by the present invention.For one of ordinary skill in the art, any apparent change of under the prerequisite that does not deviate from connotation of the present invention it being done all will consist of infringement of patent right of the present invention, will bear corresponding legal liabilities.

Claims (4)

1. unmarked some automatic positioning method of a film is characterized in that comprising the steps:
Be written into the film dosimetry data and with the planning data of the corresponding aspect of film dosimetry data;
Obtain data with planning data same pixel size by interpolation;
Choose region-of-interest;
In planning data, seek the optimum matching zone of region-of-interest by translation, rotary manipulation, obtain translation parameters and the anglec of rotation;
According to the scalability information of translation parameters, the anglec of rotation and interpolation, to described film dosimetry data travel direction operation, obtain the data that are complementary with planning data.
2. unmarked some automatic positioning method of film as claimed in claim 1 is characterized in that, the step that obtains translation parameters and the anglec of rotation further comprises:
With the region-of-interest chosen as search pattern, in planning data from top to bottom, travel through from left to right;
At each traversal point, template is done rotation process;
Under each anglec of rotation, from planning data, choose the zone consistent with postrotational template size, calculate related coefficient, obtain the related coefficient array;
In the related coefficient array, choose the related coefficient maximal value;
Obtain translation parameters and the anglec of rotation from the corresponding traversal point of described related coefficient maximal value and the anglec of rotation.
3. unmarked some automatic positioning method of film as claimed in claim 2 is characterized in that:
Obtain the optimum matching zone of region-of-interest in the planning data by described related coefficient maximal value.
4. unmarked some automatic positioning method of film as claimed in claim 1 is characterized in that, the step that obtains the data that are complementary with planning data further comprises:
Utilize translation parameters and the anglec of rotation that the film dosimetry data are done inverse operation, travel direction is proofreaied and correct;
The Pixel Dimensions ratio of film dosimetry data changes oppositely adjustment during according to interpolation, finally determines film dosimetry data and planning data to be complementary the film dosimetry data data center position corresponding with planning data in terms of content.
CN201310306652.3A 2013-07-19 2013-07-19 A kind of unmarked automatic positioning method of film Active CN103353992B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020082268A1 (en) * 2018-10-24 2020-04-30 Siemens Healthcare Gmbh Generating a medical result image

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070041499A1 (en) * 2005-07-22 2007-02-22 Weiguo Lu Method and system for evaluating quality assurance criteria in delivery of a treatment plan
CN101004834A (en) * 2006-12-29 2007-07-25 四川大学 Fault image segmentation method for images scanned from films
CN101464951A (en) * 2007-12-21 2009-06-24 北大方正集团有限公司 Image recognition method and system
CN102760285A (en) * 2012-05-31 2012-10-31 河海大学 Image restoration method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070041499A1 (en) * 2005-07-22 2007-02-22 Weiguo Lu Method and system for evaluating quality assurance criteria in delivery of a treatment plan
CN101004834A (en) * 2006-12-29 2007-07-25 四川大学 Fault image segmentation method for images scanned from films
CN101464951A (en) * 2007-12-21 2009-06-24 北大方正集团有限公司 Image recognition method and system
CN102760285A (en) * 2012-05-31 2012-10-31 河海大学 Image restoration method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020082268A1 (en) * 2018-10-24 2020-04-30 Siemens Healthcare Gmbh Generating a medical result image
US11915446B2 (en) 2018-10-24 2024-02-27 Siemens Healthineers Ag Generating a medical result image

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