Tissue characterization using intracardiac impedances with an implantable ...

<12) United States Patent

US007945326B1

(10) Patent No.: US 7,945,326 B1

Wong et al. (45) Date of Patent: May 17, 2011 (54) TISSUE CHARACTERIZATION USING 5,201,865 A 4/1993 Kuehn INTRACARDIAC IMPEDANCES WITH AN 2 gtrdrllk ml , , oes er e . IMPLANTABLE LEAD SYSTEM 5,324,309 A 6/1994 Kaiiok 5,344,429 A 9/1994 S 't (75) Inventors: Louis Wong, Sunnyvale, CA (US); Cem . ml S Shaquer San Jose CA (US)' Gene A. (commued) Bornzin, Simi Valley, CA (US); Eulj oon FOREIGN PATENT DOCUMENTS Park, Valencia, CA (U S); Andre Walker, Monte Sereno, CA (US); Dorin W0 9615827 Al _ 5/1996 Panescu, San Jose, CA (U S) (comlnued) (73) Assignee: Pacesetter, Inc., Sunnyvale, CA (US) OTHER PUBLICATIONS ( * ) Notice: Subject to any disclaimer, the term of this Aggee Action mailed May 27’ 2009: Related U'S' APPL patent is extended or adjusted under 35 ’ U.S.C. 154(b) by 411 days. (Continued) (21) Appl. No.: 11/684,677 Primary Examiner — Carl H Layno _ Assistant Examiner — Pamela M Bays (22) Feed: Mar‘ 12’ 2007 (74) Attorney, Agent, or Firm — Theresa A. Takeuchi; Related U.S. Application Data Steven M' Mltchen (60) Provisional application No. 60/787,884, filed on Mar. (57) ABSTRACT 31> 2006 An implantable system acquires intracardiac impedance with (51) I t Cl an implantable lead system. In one implementation, the sysn‘ ' t t f -'h,l , lt'-h' Am <m> ;f23§5L°‘;‘;i,-,,F$2§§;‘§ya3“Z 12-2225 (52) U.S. Cl. .................. .. 607/28; 607/2; 607/9;66é)07//51477; Voltaga when applied to bodily tissues, Current pulses Oi voltage pulses having the multi-phasic wavefonn provide Of Classification Search ................ .. increased Specificity and Sensitivity in prebing [issue The 600/547; 607/2, 8, 26, 28, 45, 76, 4, 9, 17 effects of the applied pulses are sensed as a corresponding See applicalion file for Complete Search hi5T01'Y~ waveform. The wavefonns of the applied and sensed pulses _ can be integrated to obtain corresponding area values that (56) Referenees Clted represent the current and voltage across a spectrum of fre

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