United States Patent im
 Patent Number: 4,731,051  Date of Patent: Mar. 15, 1988
 PROGRAMMABLE CONTROL MEANS FOR PROVIDING SAFE AND CONTROLLED MEDICATION INFUSION
 Inventor: Robert E. Fischell, Silver Spring, Md.
 Assignee: The Johns Hopkins University, Baltimore, Md.
 Appl. No.: 466,494
 Filed: Feb. 15,1983
Related U.S. Application Data
 Continuation-in-part of Ser. No. 34,155, Apr. 27, 1979/ Pat. No. 4,373,527.
 Int. CI." A61M 5/00
 U.S. a 604/67; 604/50;
 Field of Search 128/DIG. 12, DIG. 13;
604/891, 131, 65-66, 31, 50, 67, 245
 References Cited
U.S. PATENT DOCUMENTS
3,923,060 12/1975 Ellinwood, Jr 128/DIG. 13
4,037,598 7/1977 Georgi 128/DIG. 13
4,077,405 3/1978 Haerten et al 128/DIG. 13
4,270,532 6/1981 Franetzki et al 604/151
4,282,872 8/1981 Franetzki et al 128/213 R
4,308,866 1/1982 Jelliffee et al 128/214 E
4,373,527 2/1983 Fischell 128/260
FOREIGN PATENT DOCUMENTS 2127179 4/1984 United Kingdom .
"Microcomputer—Controlled Devices for Human Im-
plantation", R. E. Fischell, APL Technical Digest.
"The SAS-A Telenetry System", M. R. Peterson, D. C.
Zitterkopf, APL Technical Digest.
Primary Examiner—William E. Kamm
Assistant Examiner—F. Jaworski
Attorney, Agent, or Firm—Robert E. Archibald;
Howard W. Califano
An implantable programmable infusion pump (IPIP) is disclosed and generally includes: a fluid reservoir filled with selected medication; a pump for causing a precise volumetric dosage of medication to be withdrawn from the reservoir and delivered to the appropriate site within the body; and, a control means for actuating the pump in a safe and programmable manner. The control means includes a microprocessor, a permanent memory containing a series of fixed software instructions, and a memory for storing prescription schedules, dosage limits and other data. The microprocessor actuates the pump in accordance with programmable prescription parameters and dosage limits stored in the memory. A communication link allows the control means to be remotely programmed. The control means incorporates a running integral dosage limit and other safety features which prevent an inadvertent or intentional medication overdose. The control means also monitors the pump and fluid handling system and provides an alert if any improper or potentially unsafe operation is detected.
112 Claims, 22 Drawing Figures