A highly specific and versatile surface chemistry for immobilization of amine-terminated probes is disclosed. A bi-layered polymer thin film serves as the platform for coupling the probes, which are preferably oligonucleotides. The process involves sequentially coating a substrate with polyamine and...http://www.google.ca/patents/US7989396?utm_source=gb-gplus-sharePatent US7989396 - Biomolecule immobilization on biosensors