Methods and devices are provided for at least reducing the mineral content of a vascular calcified lesion, i.e. a calcified lesion present on the vascular tissue of a host. In the subject methods, the local environment of the lesion is maintained at a subphysiologic pH for a period of time sufficient...http://www.google.ca/patents/US6387071?utm_source=gb-gplus-sharePatent US6387071 - Methods and devices for reducing the mineral content of vascular calcified lesions