DNA chips containing arrays of oligonucleotide probes can be used to determine whether a target nucleic acid has a nucleotide sequence identical to or different from a specific reference sequence. The array of probes comprises probes exactly complementary to the reference sequence, as well...http://www.google.ca/patents/US5837832?utm_source=gb-gplus-sharePatent US5837832 - Arrays of nucleic acid probes on biological chips
