A biological substrate, e.g., microfluidic chip. The substrate includes a rigid substrate material, which has a surface region capable of acting as a handle substrate. The substrate also has a deformable fluid layer coupled to the surface region. One or more well regions are formed in a first portion...http://www.google.ca/patents/US7695683?utm_source=gb-gplus-sharePatent US7695683 - Method and system for microfluidic device and imaging thereof