Disclosed are synthetic, modified oligonucleotides complementary to, and capable of down-regulating the expression of, nucleic acid encoding protein kinase A subunit RIα. The modified oligonucleotides have from about 15 to about 30 nucleotides and are hybrid, inverted hybrid, or inverted chimeric oligonucleotides....http://www.google.ca/patents/US7074768?utm_source=gb-gplus-sharePatent US7074768 - Modified protein kinase A-specific oligonucleotides and methods of their use
