A device comprising a substrate having a surface for contacting blood wherein the surface has a continuum of thrombus-resistant polymeric material coated on and extending into the substrate to anchor the coating thereon. The device may be prepared by a method comprising: ...http://www.google.ca/patents/US20020169493?utm_source=gb-gplus-sharePatent US20020169493 - Anti-thrombogenic coatings for biomedical devices