WO2011139595A3 - Elongated biodegradable depot for sustained drug release to treat chronic pelvic pain - Google Patents
Elongated biodegradable depot for sustained drug release to treat chronic pelvic pain Download PDFInfo
- Publication number
- WO2011139595A3 WO2011139595A3 PCT/US2011/033545 US2011033545W WO2011139595A3 WO 2011139595 A3 WO2011139595 A3 WO 2011139595A3 US 2011033545 W US2011033545 W US 2011033545W WO 2011139595 A3 WO2011139595 A3 WO 2011139595A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polymeric substrate
- drug release
- elongated
- pelvic pain
- treat chronic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3401—Puncturing needles for the peridural or subarachnoid space or the plexus, e.g. for anaesthesia
Abstract
The invention describes a device for administering a therapeutic agent to a subject at a sustained rate over a period of time, the device being shaped, sized and adapted for administering the therapeutic agent into the region of the spinal column of the subject, the device comprising: an elongated first polymeric substrate having a proximal end, a distal end and diameter or width of about 1 mm to about 10 mm and a length of about 4 cm to about 35 cm; optionally, an elongated second polymeric substrate positioned within the first polymeric substrate; and at least one therapeutic agent, loaded into or onto the first polymeric substrate or second polymeric substrate or both, wherein the therapeutic agent is available for diffusion into the region of the spinal column of the subject.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32843610P | 2010-04-27 | 2010-04-27 | |
US61/328,436 | 2010-04-27 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2011139595A2 WO2011139595A2 (en) | 2011-11-10 |
WO2011139595A3 true WO2011139595A3 (en) | 2012-05-31 |
WO2011139595A4 WO2011139595A4 (en) | 2012-08-16 |
Family
ID=44904311
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/033545 WO2011139595A2 (en) | 2010-04-27 | 2011-04-22 | Elongated biodegradable depot for sustained drug release to treat chronic pelvic pain |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011139595A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
US20100239632A1 (en) | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
CA2890270A1 (en) * | 2012-11-01 | 2014-05-08 | Torrent Pharmaceuticals Ltd | Pharmaceutical composition of tapentadol for parenteral administration |
US10195153B2 (en) | 2013-08-12 | 2019-02-05 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
ITMI20131453A1 (en) * | 2013-09-05 | 2015-03-06 | Francesco Ugo Prada | ULTRA-COMPATIBLE ARTIFICIAL CRANIOTOMIC OPERCOLO |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
DK3169315T3 (en) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Liquid-filled dosage form to prevent immediate release abuse |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
CN107789628B (en) * | 2016-12-29 | 2021-07-23 | 天津键凯科技有限公司 | Application of conjugate of polyethylene glycol and local anesthetic in non-anesthesia analgesia |
WO2021237321A1 (en) * | 2020-05-29 | 2021-12-02 | Luiz Peracchi Edson | Long-lasting reabsorbable subcutaneous implant with sustained release of pre-concentrated pharmacologically active substance in polymer for the treatment of chronic adrenal insufficiency or hypocortisolism |
JP2023542784A (en) | 2020-07-25 | 2023-10-12 | ファーマフィナ アイラック サティス ヴェエ パザルラマ アノニム シルケティ | Combinations of drugs in parenteral dosage forms for long-term anesthesia |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050033295A1 (en) * | 2003-08-08 | 2005-02-10 | Paul Wisnewski | Implants formed of shape memory polymeric material for spinal fixation |
US20090123508A1 (en) * | 2007-10-04 | 2009-05-14 | Boston Scientific Scimed, Inc. | Implantable Drug Depot for Intrathecal Drug Delivery System for Pain Management |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
US4917686A (en) | 1985-12-16 | 1990-04-17 | Colorado Biomedical, Inc. | Antimicrobial device and method |
US5245098A (en) | 1992-01-21 | 1993-09-14 | The University Of Akron | Process for preparation of non-conjugated diolefins |
CA2316945A1 (en) | 1998-02-23 | 1999-08-26 | Mnemoscience Gmbh | Shape memory polymers |
JP2004530573A (en) | 2001-01-24 | 2004-10-07 | ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド | Shape of ophthalmic lens using shape memory polymer or shape memory alloy and method of manufacturing ophthalmic product using the shape |
DE10217350C1 (en) | 2002-04-18 | 2003-12-18 | Mnemoscience Gmbh | polyesterurethanes |
US7557167B2 (en) | 2006-09-28 | 2009-07-07 | Gore Enterprise Holdings, Inc. | Polyester compositions, methods of manufacturing said compositions, and articles made therefrom |
-
2011
- 2011-04-22 WO PCT/US2011/033545 patent/WO2011139595A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050033295A1 (en) * | 2003-08-08 | 2005-02-10 | Paul Wisnewski | Implants formed of shape memory polymeric material for spinal fixation |
US20090123508A1 (en) * | 2007-10-04 | 2009-05-14 | Boston Scientific Scimed, Inc. | Implantable Drug Depot for Intrathecal Drug Delivery System for Pain Management |
Non-Patent Citations (1)
Title |
---|
BEHL M., LENDLEIN A.: "Shape-memory polymers", MATERIALS TODAY, vol. 10, no. 4, 30 April 2007 (2007-04-30), pages 20 - 28, XP002672786 * |
Also Published As
Publication number | Publication date |
---|---|
WO2011139595A4 (en) | 2012-08-16 |
WO2011139595A2 (en) | 2011-11-10 |
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