WO2011123745A3 - Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3 - Google Patents

Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3 Download PDF

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Publication number
WO2011123745A3
WO2011123745A3 PCT/US2011/030873 US2011030873W WO2011123745A3 WO 2011123745 A3 WO2011123745 A3 WO 2011123745A3 US 2011030873 W US2011030873 W US 2011030873W WO 2011123745 A3 WO2011123745 A3 WO 2011123745A3
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Prior art keywords
csf3
colony
stimulating factor
inhibition
treatment
Prior art date
Application number
PCT/US2011/030873
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French (fr)
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WO2011123745A2 (en
Inventor
Joseph Collard
Olga Khorkova Sherman
Original Assignee
Opko Curna Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES11763493.1T priority Critical patent/ES2657969T3/en
Priority to EP11763493.1A priority patent/EP2553098B1/en
Priority to RU2012142142A priority patent/RU2612884C2/en
Priority to KR1020127026377A priority patent/KR101877065B1/en
Priority to CA2795145A priority patent/CA2795145C/en
Priority to US13/638,954 priority patent/US8980856B2/en
Application filed by Opko Curna Llc filed Critical Opko Curna Llc
Priority to CN201180021365.7A priority patent/CN102869777B/en
Priority to JP2013502879A priority patent/JP5973419B2/en
Publication of WO2011123745A2 publication Critical patent/WO2011123745A2/en
Publication of WO2011123745A3 publication Critical patent/WO2011123745A3/en
Priority to US14/618,134 priority patent/US9382538B2/en
Priority to US15/175,607 priority patent/US9920369B2/en

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Abstract

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Colony-stimulating factor 3 (CSF3), in particular, by targeting natural antisense polynucleotides of Colony-stimulating factor 3 (CSF3). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of CSF3.
PCT/US2011/030873 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3 WO2011123745A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP11763493.1A EP2553098B1 (en) 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3
RU2012142142A RU2612884C2 (en) 2010-04-02 2011-04-01 Treatment of diseases associated with colonystimulating factor 3 (csf3) by inhibition of natural antisense transcript to csf3
KR1020127026377A KR101877065B1 (en) 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3
CA2795145A CA2795145C (en) 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3
US13/638,954 US8980856B2 (en) 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3
ES11763493.1T ES2657969T3 (en) 2010-04-02 2011-04-01 Treatment of diseases related to Colony Stimulating Factor 3 (CSF3) by inhibition of the natural antisense transcript to CSF3
CN201180021365.7A CN102869777B (en) 2010-04-02 2011-04-01 CSF3 relevant diseases are treated by inhibiting the natural antisense transcript of colony stimulating factor 3 (CSF3)
JP2013502879A JP5973419B2 (en) 2010-04-02 2011-04-01 Treatment of CSF3-related diseases by inhibition of natural antisense transcripts against colony stimulating factor 3 (CSF3)
US14/618,134 US9382538B2 (en) 2010-04-02 2015-02-10 Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3
US15/175,607 US9920369B2 (en) 2010-04-02 2016-06-07 Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisene transcript to CSF3

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32041410P 2010-04-02 2010-04-02
US61/320,414 2010-04-02

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/638,954 A-371-Of-International US8980856B2 (en) 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3
US14/618,134 Division US9382538B2 (en) 2010-04-02 2015-02-10 Treatment of colony-stimulating factor 3 (CSF3) related diseases by inhibition of natural antisense transcript to CSF3

Publications (2)

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WO2011123745A2 WO2011123745A2 (en) 2011-10-06
WO2011123745A3 true WO2011123745A3 (en) 2012-04-19

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PCT/US2011/030873 WO2011123745A2 (en) 2010-04-02 2011-04-01 Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3

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Country Link
US (3) US8980856B2 (en)
EP (1) EP2553098B1 (en)
JP (1) JP5973419B2 (en)
KR (1) KR101877065B1 (en)
CN (1) CN102869777B (en)
CA (1) CA2795145C (en)
ES (1) ES2657969T3 (en)
RU (1) RU2612884C2 (en)
TW (1) TWI600759B (en)
WO (1) WO2011123745A2 (en)

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AU2011325956B2 (en) 2010-11-12 2016-07-14 The General Hospital Corporation Polycomb-associated non-coding RNAs
JP2015518713A (en) 2012-05-16 2015-07-06 ラナ セラピューティクス インコーポレイテッド Compositions and methods for modulating UTRN expression
CA2873794A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions and methods for modulating smn gene family expression
CN104583398A (en) 2012-05-16 2015-04-29 Rana医疗有限公司 Compositions and methods for modulating gene expression
EP2850188A4 (en) 2012-05-16 2016-01-20 Rana Therapeutics Inc Compositions and methods for modulating hemoglobin gene family expression
WO2013173598A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics, Inc. Compositions and methods for modulating atp2a2 expression
EA201492116A1 (en) 2012-05-16 2015-05-29 Рана Терапьютикс, Инк. COMPOSITIONS AND METHODS FOR MODULATING THE EXPRESSION OF MECP2
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
CA2966044A1 (en) 2014-10-30 2016-05-06 The General Hospital Corporation Methods for modulating atrx-dependent gene repression
US10900036B2 (en) 2015-03-17 2021-01-26 The General Hospital Corporation RNA interactome of polycomb repressive complex 1 (PRC1)
CN108148908B (en) * 2018-03-16 2020-05-12 中国人民解放军沈阳军区总医院 Application of molecular marker for diagnosing atherosclerotic renal artery stenosis
WO2022055334A1 (en) * 2020-09-14 2022-03-17 주식회사 에프엔씨티바이오텍 Composition for preventing or treating pulmonary fibrosis disease

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