WO2011008733A3 - Multi-density polymeric interbody spacer and method for fabrication thereof - Google Patents

Multi-density polymeric interbody spacer and method for fabrication thereof Download PDF

Info

Publication number
WO2011008733A3
WO2011008733A3 PCT/US2010/041790 US2010041790W WO2011008733A3 WO 2011008733 A3 WO2011008733 A3 WO 2011008733A3 US 2010041790 W US2010041790 W US 2010041790W WO 2011008733 A3 WO2011008733 A3 WO 2011008733A3
Authority
WO
WIPO (PCT)
Prior art keywords
density
interbody spacer
region
polymeric interbody
regions
Prior art date
Application number
PCT/US2010/041790
Other languages
French (fr)
Other versions
WO2011008733A2 (en
Inventor
M.D. Richard J. Deslauriers
Joseph Jannetty
Eric Kolb
John A. Tomich
Naresh Akkarapaka
Original Assignee
Doctors Research Group, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/502,597 external-priority patent/US20110015743A1/en
Priority claimed from US12/502,635 external-priority patent/US20110012280A1/en
Application filed by Doctors Research Group, Inc. filed Critical Doctors Research Group, Inc.
Priority to EP10800407A priority Critical patent/EP2453937A2/en
Priority to AU2010273530A priority patent/AU2010273530A1/en
Priority to CA2767822A priority patent/CA2767822A1/en
Publication of WO2011008733A2 publication Critical patent/WO2011008733A2/en
Publication of WO2011008733A3 publication Critical patent/WO2011008733A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/003—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor characterised by the choice of material
    • B29C39/006—Monomers or prepolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146—Porous materials, e.g. foams or sponges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/021—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles by casting in several steps
    • B29C39/025—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles by casting in several steps for making multilayered articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/10—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. casting around inserts or for coating articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses

Abstract

A multi-density polymeric interbody spacer formed from biocompatible material for osteoconductivity includes multiple density regions of different porosity to provide both strength and osteoconductivity. An interface region is formed between the density regions to provide both direct adhesion and mechanical interlocking between the different density regions to increase the strength of the multi-density polymeric interbody spacer. A method for forming the multi-density polymeric interbody spacer includes curing a first density region to achieve a first target porosity. A second density region may then be molded to the first density region to achieve a second target porosity. A portion of the second density region partially flows into pores of the first density region, providing direct adhesion and mechanical interlocking between the first and second density regions.
PCT/US2010/041790 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof WO2011008733A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP10800407A EP2453937A2 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof
AU2010273530A AU2010273530A1 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof
CA2767822A CA2767822A1 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/502,635 2009-07-14
US12/502,597 2009-07-14
US12/502,597 US20110015743A1 (en) 2009-07-14 2009-07-14 Multi-density polymeric interbody spacer
US12/502,635 US20110012280A1 (en) 2009-07-14 2009-07-14 Method for fabricating a multi-density polymeric interbody spacer

Publications (2)

Publication Number Publication Date
WO2011008733A2 WO2011008733A2 (en) 2011-01-20
WO2011008733A3 true WO2011008733A3 (en) 2011-07-07

Family

ID=43450130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/041790 WO2011008733A2 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof

Country Status (4)

Country Link
EP (1) EP2453937A2 (en)
AU (1) AU2010273530A1 (en)
CA (1) CA2767822A1 (en)
WO (1) WO2011008733A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5942076B2 (en) 2010-11-10 2016-06-29 三菱マテリアル株式会社 Vertebral spacer
GB2545819B (en) 2010-11-10 2018-01-10 Mitsubishi Materials Corp Vertebral body spacer
JP5942075B2 (en) 2010-11-10 2016-06-29 三菱マテリアル株式会社 Vertebral spacer
CN103239282A (en) * 2012-02-10 2013-08-14 北京爱康宜诚医疗器材股份有限公司 Vertebral body union internal fixation system
WO2023091346A1 (en) * 2021-11-17 2023-05-25 Acuity Surgical Devices Llc Method and apparatus for reducing human vertebral body subsidence using variable surface area interbody cages correlated to localized bone density measurements
WO2023230119A1 (en) * 2022-05-24 2023-11-30 Dsm Ip Assets B.V. Joint spacers

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607474A (en) * 1992-02-14 1997-03-04 Board Of Regents, University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US6149688A (en) * 1995-06-07 2000-11-21 Surgical Dynamics, Inc. Artificial bone graft implant
US6482234B1 (en) * 2000-04-26 2002-11-19 Pearl Technology Holdings, Llc Prosthetic spinal disc
US20030004578A1 (en) * 2001-06-28 2003-01-02 Ethicon, Inc. Composite scaffold with post anchor for the repair and regeneration of tissue
US20040249462A1 (en) * 2003-06-06 2004-12-09 Shih-Shing Huang Artificial intervertebral disc flexibly oriented by spring-reinforced bellows
US20050228498A1 (en) * 2003-11-18 2005-10-13 Todd Andres Osteoconductive integrated spinal cage and method of making same
US20090043398A1 (en) * 2007-08-09 2009-02-12 Zimmer, Inc. Method of producing gradient articles by centrifugation molding or casting

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607474A (en) * 1992-02-14 1997-03-04 Board Of Regents, University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US6149688A (en) * 1995-06-07 2000-11-21 Surgical Dynamics, Inc. Artificial bone graft implant
US6482234B1 (en) * 2000-04-26 2002-11-19 Pearl Technology Holdings, Llc Prosthetic spinal disc
US20030004578A1 (en) * 2001-06-28 2003-01-02 Ethicon, Inc. Composite scaffold with post anchor for the repair and regeneration of tissue
US20040249462A1 (en) * 2003-06-06 2004-12-09 Shih-Shing Huang Artificial intervertebral disc flexibly oriented by spring-reinforced bellows
US20050228498A1 (en) * 2003-11-18 2005-10-13 Todd Andres Osteoconductive integrated spinal cage and method of making same
US20090043398A1 (en) * 2007-08-09 2009-02-12 Zimmer, Inc. Method of producing gradient articles by centrifugation molding or casting

Also Published As

Publication number Publication date
WO2011008733A2 (en) 2011-01-20
CA2767822A1 (en) 2011-01-20
EP2453937A2 (en) 2012-05-23
AU2010273530A1 (en) 2012-02-09

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