Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.


  1. Advanced Patent Search
Publication numberWO2009083648 A3
Publication typeApplication
Application numberPCT/FI2008/050781
Publication date3 Sep 2009
Filing date22 Dec 2008
Priority date27 Dec 2007
Also published asDE112008003552T5, DE112008003552T9, WO2009083648A2
Publication numberPCT/2008/50781, PCT/FI/2008/050781, PCT/FI/2008/50781, PCT/FI/8/050781, PCT/FI/8/50781, PCT/FI2008/050781, PCT/FI2008/50781, PCT/FI2008050781, PCT/FI200850781, PCT/FI8/050781, PCT/FI8/50781, PCT/FI8050781, PCT/FI850781, WO 2009/083648 A3, WO 2009083648 A3, WO 2009083648A3, WO-A3-2009083648, WO2009/083648A3, WO2009083648 A3, WO2009083648A3
InventorsDavid A. Cohen, Michael J. Mortillaro, Charles Patrick André
ApplicantFinnzymes Instruments Oy
Export CitationBiBTeX, EndNote, RefMan
External Links: Patentscope, Espacenet
Thermal cycling instrument and methods for carrying out pcr
WO 2009083648 A3
The invention relates to a polymerase chain reaction (PCR) process and a thermal cycler. In the process, biological samples are held in a sample carrier (10) having a plurality of sample spaces (12) each having upper and lower ends and the samples are sequentially heated and cooled. The thermal cycler according to the invention comprises heat transfer means for automatic heating and cooling of the samples in the sample carrier, heatable closure means (18) above the upper ends of the samples spaces (12) for preventing condensation of sample vapor during the process, and means for adjusting one process parameter, preferably the temperature of the heatable closure means, depending on at least one other of said process parameters. The invention helps to decrease the number of failed PCR experiments in particular due to changes in sample volume.
Non-Patent Citations
1 *BIO-RAD LABORATORIES, INC.: "MJ Mini Gradient Thermal Cycler. Operations Manual"[Online] 2005, pages 1-96, XP002530917 Retrieved from the Internet: URL:> [retrieved on 2009-06-14]
2 *FINNZYMES INSTRUMENT: "Piko Thermal Cycler. User Manual."[Online] October 2007 (2007-10), pages 1-14, XP002530918 Retrieved from the Internet: URL:> [retrieved on 2009-06-14]
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US825258122 Jan 200828 Aug 2012Wafergen, Inc.Apparatus for high throughput chemical reactions
US913242724 Aug 201215 Sep 2015Wafergen, Inc.Apparatus for high throughput chemical reactions
US922893323 Nov 20095 Jan 2016Wafergen, Inc.Apparatus and method for multiplex analysis
International ClassificationB01L7/00
Cooperative ClassificationB01L2200/142, B01L3/50853, B01L7/52, B01L3/50851, B01L2300/046, B01L2300/0829
European ClassificationB01L3/50851, B01L3/50853, B01L7/52
Legal Events
2 Sep 2009121Ep: the epo has been informed by wipo that ep was designated in this application
Ref document number: 08868032
Country of ref document: EP
Kind code of ref document: A2
30 Jun 2010WWEWipo information: entry into national phase
Ref document number: 1120080035520
Country of ref document: DE
19 Jul 2010ENPEntry into the national phase in:
Ref document number: 1012081
Country of ref document: GB
Kind code of ref document: A
Free format text: PCT FILING DATE = 20081222
28 Oct 2010RETDe translation (de og part 6b)
Ref document number: 112008003552
Country of ref document: DE
Date of ref document: 20101028
Kind code of ref document: P
26 Jan 2011122Ep: pct app. not ent. europ. phase
Ref document number: 08868032
Country of ref document: EP
Kind code of ref document: A2