WO2009032760A3 - Electrochmical sensor and method for manufacturing - Google Patents

Electrochmical sensor and method for manufacturing Download PDF

Info

Publication number
WO2009032760A3
WO2009032760A3 PCT/US2008/074644 US2008074644W WO2009032760A3 WO 2009032760 A3 WO2009032760 A3 WO 2009032760A3 US 2008074644 W US2008074644 W US 2008074644W WO 2009032760 A3 WO2009032760 A3 WO 2009032760A3
Authority
WO
WIPO (PCT)
Prior art keywords
elongated member
insulating layer
sensed
sensor
transverse cross
Prior art date
Application number
PCT/US2008/074644
Other languages
French (fr)
Other versions
WO2009032760A2 (en
Inventor
James L Say
Original Assignee
Pepex Biomedical Llc
James L Say
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pepex Biomedical Llc, James L Say filed Critical Pepex Biomedical Llc
Priority to US12/674,858 priority Critical patent/US8702932B2/en
Publication of WO2009032760A2 publication Critical patent/WO2009032760A2/en
Publication of WO2009032760A3 publication Critical patent/WO2009032760A3/en
Priority to US14/257,727 priority patent/US9459228B2/en
Priority to US15/254,423 priority patent/US11150212B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction

Abstract

The present disclosure relates to a sensor including an elongated member including at least a portion that is electrically conductive. The elongated member includes a sensing layer adapted to react with a material desired to be sensed. An insulating layer surrounds the elongated member. The insulating layer defines at least one access opening for allowing the material desired to be sensed to enter an interior region defined between the elongated member and the insulating layer. The insulating layer has an inner transverse cross-sectional profile that is different from an outer transverse cross-sectional profile of the elongated member. The difference in transverse cross-sectional profiles between the elongated member and the insulating layer provides channels at the interior region defined between the insulating layer and the elongated member. The channels extend generally along the length of the elongated member and are sized to allow the material desired to be sensed to move along the length of the sensor.
PCT/US2008/074644 2007-08-30 2008-08-28 Electrochmical sensor and method for manufacturing WO2009032760A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/674,858 US8702932B2 (en) 2007-08-30 2008-08-28 Electrochemical sensor and method for manufacturing
US14/257,727 US9459228B2 (en) 2007-08-30 2014-04-21 Electrochemical sensor and method for manufacturing
US15/254,423 US11150212B2 (en) 2007-08-30 2016-09-01 Electrochemical sensor and method for manufacturing

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96903407P 2007-08-30 2007-08-30
US60/969,034 2007-08-30

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/674,858 A-371-Of-International US8702932B2 (en) 2007-08-30 2008-08-28 Electrochemical sensor and method for manufacturing
US14/257,727 Continuation US9459228B2 (en) 2007-08-30 2014-04-21 Electrochemical sensor and method for manufacturing

Publications (2)

Publication Number Publication Date
WO2009032760A2 WO2009032760A2 (en) 2009-03-12
WO2009032760A3 true WO2009032760A3 (en) 2009-06-25

Family

ID=40020270

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/074644 WO2009032760A2 (en) 2007-08-30 2008-08-28 Electrochmical sensor and method for manufacturing

Country Status (2)

Country Link
US (3) US8702932B2 (en)
WO (1) WO2009032760A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9044178B2 (en) 2007-08-30 2015-06-02 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
WO2009032760A2 (en) 2007-08-30 2009-03-12 Pepex Biomedical Llc Electrochmical sensor and method for manufacturing
US8506740B2 (en) 2008-11-14 2013-08-13 Pepex Biomedical, Llc Manufacturing electrochemical sensor module
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
US8721850B2 (en) * 2010-02-02 2014-05-13 Roche Diagnostics Operations, Inc. Biosensor and methods for manufacturing
WO2012159040A2 (en) 2011-05-19 2012-11-22 Pepex Biomedical Inc. Fluid management and patient monitoring system
WO2012162151A2 (en) 2011-05-20 2012-11-29 Pepex Biomedical, Inc. Manufacturing electrochemical sensor modules
WO2014089058A1 (en) * 2012-12-03 2014-06-12 Pepex Biomedical, Inc. Sensor module and method of using a sensor module
US11045124B2 (en) 2014-06-04 2021-06-29 Pepex Biomedical, Inc. Electrochemical sensors and methods for making electrochemical sensors using advanced printing technology
GB2582906B (en) * 2019-04-01 2022-09-07 Ip2Ipo Innovations Ltd Electrochemical sensor cable
CN113857012B (en) * 2021-09-27 2023-07-28 常熟五临天光电科技有限公司 Illumination processing system convenient to air is got rid of

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989007139A1 (en) * 1988-02-05 1989-08-10 Novo-Nordisk A/S A method for immobilizing a polypeptide in a polymer and a membrane produced thereby
WO1991015993A1 (en) * 1990-04-19 1991-10-31 The University Of Kansas Implantable glucose sensor
EP0965301A1 (en) * 1998-06-11 1999-12-22 Matsushita Electric Industrial Co., Ltd. Electrode probe and body fluid examination equipment including the same
US6464849B1 (en) * 1999-10-07 2002-10-15 Pepex Biomedical, L.L.C. Sensor for measuring a bioanalyte such as lactate
WO2005051183A1 (en) * 2003-11-25 2005-06-09 Novo Nordisk A/S A needle sensor and a mechanism for inserting the needle sensor through the skin
US6965791B1 (en) * 2003-03-26 2005-11-15 Sorenson Medical, Inc. Implantable biosensor system, apparatus and method
WO2007091633A1 (en) * 2006-02-09 2007-08-16 The University Of Tokushima Biodevice, contact part structure of biodevice, and biosensor

Family Cites Families (228)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH103938A (en) * 1923-01-29 1924-03-17 Meirowsky & Co Aktiengesellsch Method for applying liquid substances to wire and thread-like bodies.
US2291720A (en) * 1939-12-27 1942-08-04 Anaconda Wire & Cable Co Die suspension
US3170968A (en) * 1961-03-31 1965-02-23 Nippon Telegraph & Telephone Method of manufacturing cellular insulated wire
US3766910A (en) 1970-10-09 1973-10-23 P Lake Disposable delicate tissue retractor
CA995071A (en) 1972-07-14 1976-08-17 Dow Badische Company Electrically-conductive textile fiber
US3908657A (en) 1973-01-15 1975-09-30 Univ Johns Hopkins System for continuous withdrawal of blood
US4073974A (en) * 1975-07-31 1978-02-14 Bell Telephone Laboratories, Incorporated Coating continuous filaments
USRE33677E (en) * 1976-05-26 1991-08-27 Coating of fiber lightguides with UV cured polymerization
US4255487A (en) 1977-05-10 1981-03-10 Badische Corporation Electrically conductive textile fiber
JPS5912135B2 (en) * 1977-09-28 1984-03-21 松下電器産業株式会社 enzyme electrode
US4321057A (en) * 1979-09-20 1982-03-23 Buckles Richard G Method for quantitative analysis using optical fibers
US4399099A (en) * 1979-09-20 1983-08-16 Buckles Richard G Optical fiber apparatus for quantitative analysis
DE3278334D1 (en) 1981-10-23 1988-05-19 Genetics Int Inc Sensor for components of a liquid mixture
US4439303A (en) * 1982-06-28 1984-03-27 Maurice Cocchi Crystallographically-oriented spatially-dispersed conductive fiber electrode
US4552840A (en) 1982-12-02 1985-11-12 California And Hawaiian Sugar Company Enzyme electrode and method for dextran analysis
US4545835A (en) 1983-06-15 1985-10-08 Badische Corporation Method of forming supported antistatic yarn
JPS605736U (en) 1983-06-23 1985-01-16 日立電線株式会社 Wire feeding device for cylindrical stranding machine
US4762603A (en) * 1983-06-24 1988-08-09 American Cyanamid Company Process for forming electrodes
US4573968A (en) 1983-08-16 1986-03-04 Ivac Corporation Infusion and blood chemistry monitoring system
US4545283A (en) 1983-09-08 1985-10-08 Sackner Products, Inc. Upholstery welt cord
US4820399A (en) * 1984-08-31 1989-04-11 Shimadzu Corporation Enzyme electrodes
US4601881A (en) 1984-11-01 1986-07-22 Allied Corporation Liquid handling system
US5171689A (en) 1984-11-08 1992-12-15 Matsushita Electric Industrial Co., Ltd. Solid state bio-sensor
US4671288A (en) 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4640821A (en) 1985-07-16 1987-02-03 Fisher Scientific Company Analysis apparatus
US4734184A (en) 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
US4805624A (en) 1985-09-09 1989-02-21 The Montefiore Hospital Association Of Western Pa Low-potential electrochemical redox sensors
GB8522834D0 (en) * 1985-09-16 1985-10-23 Ici Plc Sensor
US4704311A (en) 1985-12-04 1987-11-03 Basf Corporation Process for making electrically conductive textile filaments
WO1987006701A1 (en) 1986-04-22 1987-11-05 Toray Industries, Inc. Microelectrode for electrochemical analysis
US5001054A (en) * 1986-06-26 1991-03-19 Becton, Dickinson And Company Method for monitoring glucose
US4981779A (en) * 1986-06-26 1991-01-01 Becton, Dickinson And Company Apparatus for monitoring glucose
JPS636451A (en) 1986-06-27 1988-01-12 Terumo Corp Enzyme sensor
SE451894B (en) 1986-08-15 1987-11-02 Gambro Ab ANALYTICAL SYSTEM CONTAINING MEASURES FOR BLOOD SAMPLING, AND FOR CONDUCTING PREVENT A METAL ELECTRODE, AND FOR SUPPLY OF DILUTING OR ANTICOAGULATING FLUID
US4807640A (en) * 1986-11-19 1989-02-28 Respitrace Corporation Stretchable band-type transducer particularly suited for respiration monitoring apparatus
US5004583A (en) 1987-01-29 1991-04-02 Medtest Systems, Inc. Universal sensor cartridge for use with a universal analyzer for sensing components in a multicomponent fluid
US4846548A (en) * 1987-05-06 1989-07-11 St&E, Inc. Fiber optic which is an inherent chemical sensor
US4833083A (en) * 1987-05-26 1989-05-23 Sepragen Corporation Packed bed bioreactor
JPS643552A (en) 1987-06-26 1989-01-09 Terumo Corp Enzyme sensor
AU604364B2 (en) 1987-08-13 1990-12-13 Dow Chemical Company, The Sulfur dioxide removal from gas streams using hydroxyalkyl substituted piperazinones
US4974929A (en) 1987-09-22 1990-12-04 Baxter International, Inc. Fiber optical probe connector for physiologic measurement devices
US4919649A (en) 1987-09-30 1990-04-24 Sherwood Medical Company Fluid delivery system
US4824206A (en) * 1987-11-25 1989-04-25 St&E, Inc. Modular fiber optic chemical sensor
JPH01153952A (en) 1987-12-11 1989-06-16 Terumo Corp Enzyme sensor
JP2672561B2 (en) 1988-01-29 1997-11-05 テルモ株式会社 Membrane cover sensor
EP0327658B1 (en) 1988-02-11 1991-10-23 Hewlett-Packard GmbH Sample injector for a liquid chromatograph
JPH01263537A (en) 1988-04-15 1989-10-20 Nok Corp Fiber-shaped sensor and evaluating device thereof
US4995402A (en) 1988-10-12 1991-02-26 Thorne, Smith, Astill Technologies, Inc. Medical droplet whole blood and like monitoring
US4945896A (en) 1989-01-24 1990-08-07 Gade George F Surgical retractor assembly having tissue viability sensor embedded therein
US5205920A (en) * 1989-03-03 1993-04-27 Noboru Oyama Enzyme sensor and method of manufacturing the same
US5002651A (en) * 1989-03-07 1991-03-26 University Of Connecticut Modified microelectrodes with renewable surface and method of making same
DK115989D0 (en) 1989-03-09 1989-03-09 Nordisk Gentofte METHOD AND METHOD FOR MEASURING A LIQUID COMPONENT
US5269891A (en) 1989-03-09 1993-12-14 Novo Nordisk A/S Method and apparatus for determination of a constituent in a fluid
DE3923950A1 (en) 1989-07-19 1991-01-31 Biotechnolog Forschung Gmbh FIBER OPTICAL SENSOR ARRANGEMENT FOR DETERMINING AN ANALYTIC, IN PARTICULAR OF GLUCOSE
US5264105A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
US5320725A (en) * 1989-08-02 1994-06-14 E. Heller & Company Electrode and method for the detection of hydrogen peroxide
US5262035A (en) 1989-08-02 1993-11-16 E. Heller And Company Enzyme electrodes
US5264104A (en) 1989-08-02 1993-11-23 Gregg Brian A Enzyme electrodes
US5985129A (en) 1989-12-14 1999-11-16 The Regents Of The University Of California Method for increasing the service life of an implantable sensor
US5286362A (en) 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
US5131138A (en) * 1990-03-23 1992-07-21 Optoswitch, Inc. Method of manufacturing an optical micro-switch apparatus
AT398694B (en) 1990-07-19 1995-01-25 Avl Verbrennungskraft Messtech DEVICE FOR DETERMINING THE CONCENTRATION OF AT LEAST ONE SUBSTANCE IN ORGANIC TISSUE
US5112455A (en) 1990-07-20 1992-05-12 I Stat Corporation Method for analytically utilizing microfabricated sensors during wet-up
US5271073A (en) 1990-08-10 1993-12-14 Puritan-Bennett Corporation Optical fiber sensor and method of manufacture
CA2050677C (en) 1990-09-06 2003-04-08 Ernest J. Kiser Visual blood glucose concentration test strip
US5165406A (en) 1990-09-13 1992-11-24 Via Medical Corporation Electrochemical sensor apparatus and method
CA2053449A1 (en) * 1990-10-16 1992-04-17 Henry K. Hui Optical fiber ph microsensor and method of manufacture
NL9002764A (en) * 1990-12-14 1992-07-01 Tno ELECTRODE, FITTED WITH A POLYMER COATING WITH A REDOX ENZYM BOND TO IT.
US5244636A (en) 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5320814A (en) * 1991-01-25 1994-06-14 Trustees Of Tufts College Fiber optic array sensors, apparatus, and methods for concurrently visualizing and chemically detecting multiple analytes of interest in a fluid sample
US5250264A (en) 1991-01-25 1993-10-05 Trustees Of Tufts College Method of making imaging fiber optic sensors to concurrently detect multiple analytes of interest in a fluid sample
DE4105222A1 (en) 1991-02-20 1992-08-27 Schaefer Wieland Dr Sc Single rod micro measurement chain for in vivo pharmacological use - has carbon fibre microelectrodes mounted on surface of metal counter electrode with insulation
JPH04278450A (en) 1991-03-04 1992-10-05 Adam Heller Biosensor and method for analyzing subject
US5593852A (en) * 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
JPH04279854A (en) 1991-03-08 1992-10-05 Tekunoroogu:Kk Platinum coated carbon fiber electrode and enzymatic film sensor using same
US5164229A (en) 1991-07-08 1992-11-17 The United States Of America As Represented By The Secretary Of The Air Force Method for coating continuous tow
US5217533A (en) * 1991-07-08 1993-06-08 The United States Of America As Represented By The Secretary Of The Air Force Coating apparatus for continuous fibers
US5264092A (en) 1991-10-02 1993-11-23 Moltech Corporation Redox polymer modified electrode for the electrochemical regeneration of coenzyme
US5264103A (en) 1991-10-18 1993-11-23 Matsushita Electric Industrial Co., Ltd. Biosensor and a method for measuring a concentration of a substrate in a sample
US5524338A (en) * 1991-10-22 1996-06-11 Pi Medical Corporation Method of making implantable microelectrode
US5220920A (en) 1991-11-08 1993-06-22 Via Medical Corporation Electrochemical measurement system having interference reduction circuit
WO1993012718A1 (en) 1991-12-23 1993-07-08 Pharmacia Deltec, Inc. Guide wire apparatus with location sensing member
US5271815A (en) 1991-12-26 1993-12-21 Via Medical Corporation Method for measuring glucose
JP3084877B2 (en) 1992-01-21 2000-09-04 松下電器産業株式会社 Manufacturing method of glucose sensor
NL9200207A (en) 1992-02-05 1993-09-01 Nedap Nv IMPLANTABLE BIOMEDICAL SENSOR DEVICE, IN PARTICULAR FOR MEASUREMENT OF THE GLUCOSE CONCENTRATION.
US5271820A (en) 1992-06-19 1993-12-21 Monsanto Company Solid state pH sensor
US5330634A (en) 1992-08-28 1994-07-19 Via Medical Corporation Calibration solutions useful for analyses of biological fluids and methods employing same
JP2541081B2 (en) 1992-08-28 1996-10-09 日本電気株式会社 Biosensor and method of manufacturing and using biosensor
US5503728A (en) 1992-09-09 1996-04-02 Agency Of Industrial Science And Technology Carbon sensor electrode and process for producing the same
EP0592805A3 (en) 1992-09-09 1996-07-24 Agency Ind Science Techn Carbon sensor electrode and process for producing the same
US5298144A (en) * 1992-09-15 1994-03-29 The Yellow Springs Instrument Company, Inc. Chemically wired fructose dehydrogenase electrodes
WO1994010553A1 (en) 1992-10-23 1994-05-11 Optex Biomedical, Inc. Fibre-optic probe for the measurement of fluid parameters
USD354559S (en) 1992-11-13 1995-01-17 Via Medical Corporation Blood chemistry sensor assembly
USD354347S (en) 1992-12-10 1995-01-10 Via Medical Corporation Blood chemistry sensor assembly
US5298741A (en) * 1993-01-13 1994-03-29 Trustees Of Tufts College Thin film fiber optic sensor array and apparatus for concurrent viewing and chemical sensing of a sample
FR2701117B1 (en) * 1993-02-04 1995-03-10 Asulab Sa Electrochemical measurement system with multizone sensor, and its application to glucose measurement.
US5366527A (en) 1993-04-05 1994-11-22 Corning Incorporated Method and apparatus for coating optical waveguide fibers
DK0622119T3 (en) * 1993-04-23 2000-04-10 Roche Diagnostics Gmbh Test element storage system
ZA948393B (en) 1993-11-01 1995-06-26 Polartechnics Ltd Method and apparatus for tissue type recognition
US5997501A (en) 1993-11-18 1999-12-07 Elan Corporation, Plc Intradermal drug delivery device
ES2148272T3 (en) 1993-12-29 2000-10-16 Mochida Pharm Co Ltd ELECTROCHEMICAL TEST METHOD AND COMPOSITE OF NEW P-PHENYLENDIAMINE.
US5431174A (en) 1994-04-04 1995-07-11 Via Medical Corporation Method of fluid delivery and collection
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
DE4422068A1 (en) 1994-06-23 1996-01-04 Siemens Ag Electro-catalytic glucose sensor in catheter form
US5605152A (en) * 1994-07-18 1997-02-25 Minimed Inc. Optical glucose sensor
US5522977A (en) * 1994-10-07 1996-06-04 Biomedix, Inc. Glucose sensor
JP3453954B2 (en) 1994-11-02 2003-10-06 トヨタ自動車株式会社 Carbon monoxide detector, organic compound detector and lower alcohol detector
US5575403A (en) 1995-01-13 1996-11-19 Bayer Corporation Dispensing instrument for fluid monitoring sensors
US5697366A (en) 1995-01-27 1997-12-16 Optical Sensors Incorporated In situ calibration system for sensors located in a physiologic line
US5691062A (en) 1995-02-16 1997-11-25 Clemson University Molecularly bonded inherently conductive polymers on substrates and shaped articles thereof
US5882494A (en) * 1995-03-27 1999-03-16 Minimed, Inc. Polyurethane/polyurea compositions containing silicone for biosensor membranes
US5518152A (en) 1995-06-06 1996-05-21 E. S. Robbins Corporation Measuring canister
US5656241A (en) * 1995-09-07 1997-08-12 Optical Sensors Incorporated Method for manufacturing fiber optic sensors
US5972199A (en) 1995-10-11 1999-10-26 E. Heller & Company Electrochemical analyte sensors using thermostable peroxidase
WO1997015827A1 (en) 1995-10-25 1997-05-01 Wilkins Ebtisam S Coated wire sensor
CA2198036C (en) 1996-02-20 2000-12-05 Charles S. Taylor Access platform for internal mammary dissection
US7828749B2 (en) 1996-05-17 2010-11-09 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
EP0906062B1 (en) * 1996-05-17 2007-12-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
US5810199A (en) 1996-06-10 1998-09-22 Bayer Corporation Dispensing instrument for fluid monitoring sensor
US5828798A (en) 1996-09-09 1998-10-27 Hopenfeld; Joram Looped fiber-optic sensor for the detection of substances
DE69809391T2 (en) * 1997-02-06 2003-07-10 Therasense Inc SMALL VOLUME SENSOR FOR IN-VITRO DETERMINATION
US5814601A (en) 1997-02-28 1998-09-29 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
EP0965031A1 (en) 1997-03-07 1999-12-22 Ericsson Inc. Voltage divider providing switchable resolution
US6375871B1 (en) * 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
US6004818A (en) 1997-08-07 1999-12-21 Chrono-Log Corporation Aggregometer with disposable test cell
US5951764A (en) 1997-08-15 1999-09-14 Hay; Randall S. Coating apparatus for continuous tow
DE19738687A1 (en) * 1997-09-04 1999-03-11 Alsthom Cge Alcatel Process for coating an optical fiber
US6071391A (en) 1997-09-12 2000-06-06 Nok Corporation Enzyme electrode structure
DE19824036A1 (en) 1997-11-28 1999-06-02 Roche Diagnostics Gmbh Analytical measuring device with lancing device
DE19753847A1 (en) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytical test element with capillary channel
US5971941A (en) 1997-12-04 1999-10-26 Hewlett-Packard Company Integrated system and method for sampling blood and analysis
US6071294A (en) * 1997-12-04 2000-06-06 Agilent Technologies, Inc. Lancet cartridge for sampling blood
US6036924A (en) * 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6103033A (en) * 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
JP3382853B2 (en) * 1998-04-09 2003-03-04 松下電器産業株式会社 Body fluid testing device
US6241863B1 (en) * 1998-04-27 2001-06-05 Harold G. Monbouquette Amperometric biosensors based on redox enzymes
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
GB9809918D0 (en) * 1998-05-08 1998-07-08 Isis Innovation Microelectrode biosensor and method therefor
CA2273467C (en) 1998-06-04 2009-02-17 Cordis Webster, Inc. Catheter for injecting therapeutic and diagnostic agents
US7344499B1 (en) * 1998-06-10 2008-03-18 Georgia Tech Research Corporation Microneedle device for extraction and sensing of bodily fluids
US6107083A (en) * 1998-08-21 2000-08-22 Bayer Corporation Optical oxidative enzyme-based sensors
US6103199A (en) * 1998-09-15 2000-08-15 Aclara Biosciences, Inc. Capillary electroflow apparatus and method
DE19844500A1 (en) * 1998-09-29 2000-03-30 Roche Diagnostics Gmbh Process for the photometric evaluation of test elements
US6591125B1 (en) * 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6128519A (en) 1998-12-16 2000-10-03 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
DE19902601A1 (en) * 1999-01-23 2000-07-27 Roche Diagnostics Gmbh Method and device for removing analytical consumables from a storage container
US6713291B2 (en) 1999-01-28 2004-03-30 Alan D. King Electrodes coated with treating agent and uses thereof
US6360888B1 (en) 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
USD426638S (en) * 1999-05-06 2000-06-13 Therasense, Inc. Glucose sensor buttons
USD424696S (en) * 1999-05-06 2000-05-09 Therasense, Inc. Glucose sensor
ATE331214T1 (en) 1999-10-07 2006-07-15 Pepex Biomedical Llc SENSOR, CONSISTING OF AN INSULATING SHEATH CONTAINING A MULTIPLE CONDUCTIVE FIBERS WHICH ARE AT LEAST PARTLY SURROUNDED BY A SENSITIVE MATERIAL AND CONTAIN VOIDS BETWEEN THE FIBERS
US6616819B1 (en) * 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
US6484045B1 (en) 2000-02-10 2002-11-19 Medtronic Minimed, Inc. Analyte sensor and method of making the same
US6706159B2 (en) * 2000-03-02 2004-03-16 Diabetes Diagnostics Combined lancet and electrochemical analyte-testing apparatus
US6375627B1 (en) 2000-03-02 2002-04-23 Agilent Technologies, Inc. Physiological fluid extraction with rapid analysis
US6620112B2 (en) 2000-03-24 2003-09-16 Novo Nordisk A/S Disposable lancet combined with a reagent carrying strip and a system for extracting and analyzing blood in the body utilizing such a disposable lancet
DE20009392U1 (en) 2000-05-25 2000-11-16 Ratzesberger Konrad Sugar meter as ear clips
US6540675B2 (en) 2000-06-27 2003-04-01 Rosedale Medical, Inc. Analyte monitor
US6561989B2 (en) * 2000-07-10 2003-05-13 Bayer Healthcare, Llc Thin lance and test sensor having same
US6500144B1 (en) 2000-09-15 2002-12-31 Scimed Life Systems, Inc. Steerable catheter and self-mounting center support for use with same
AU9658801A (en) * 2000-10-04 2002-04-15 Insulet Corp Data collection assembly for patient infusion system
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
DE10112384A1 (en) 2001-03-15 2002-09-26 Uwe Thomas Ultra-micro electrode, for use as a probe for topographical and chemical analysis, has a cylindrical body with a center electrode fiber, and parallel outer electrode fibers insulated against the center fiber
US6576102B1 (en) 2001-03-23 2003-06-10 Virotek, L.L.C. Electrochemical sensor and method thereof
US6572745B2 (en) * 2001-03-23 2003-06-03 Virotek, L.L.C. Electrochemical sensor and method thereof
US6610978B2 (en) * 2001-03-27 2003-08-26 Agilent Technologies, Inc. Integrated sample preparation, separation and introduction microdevice for inductively coupled plasma mass spectrometry
US6783502B2 (en) * 2001-04-26 2004-08-31 Phoenix Bioscience Integrated lancing and analytic device
US6676816B2 (en) * 2001-05-11 2004-01-13 Therasense, Inc. Transition metal complexes with (pyridyl)imidazole ligands and sensors using said complexes
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
DE10142232B4 (en) * 2001-08-29 2021-04-29 Roche Diabetes Care Gmbh Process for the production of an analytical aid with a lancet and test element
WO2003049609A1 (en) * 2001-12-07 2003-06-19 Micronix, Inc. Consolidated body fluid testing device and method
US20030211619A1 (en) 2002-05-09 2003-11-13 Lorin Olson Continuous strip of fluid sampling and testing devices and methods of making, packaging and using the same
US7390457B2 (en) * 2002-10-31 2008-06-24 Agilent Technologies, Inc. Integrated microfluidic array device
US20040102717A1 (en) * 2002-11-26 2004-05-27 Yan Qi Disposable automatic safety assembly means for test and/or delivery
US20040127818A1 (en) 2002-12-27 2004-07-01 Roe Steven N. Precision depth control lancing tip
US7264139B2 (en) 2003-01-14 2007-09-04 Hypoguard Limited Sensor dispensing device
ITTO20030219A1 (en) 2003-03-25 2004-09-26 Eltek Spa DEVICE FOR DETECTION OF PHYSICAL VARIABLES OF A FLUID,
US7146202B2 (en) 2003-06-16 2006-12-05 Isense Corporation Compound material analyte sensor
PT1639352T (en) 2003-06-20 2018-07-09 Hoffmann La Roche Method and reagent for producing narrow, homogenous reagent strips
ES2657627T3 (en) * 2003-06-20 2018-03-06 F. Hoffmann-La Roche Ag Electrochemical biosensors
US7460898B2 (en) * 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7424318B2 (en) 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP1658396B1 (en) 2003-08-28 2009-06-17 Sabanci Universitesi Metal coated nano fibres
US7723099B2 (en) 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US20050089944A1 (en) * 2003-10-27 2005-04-28 Biomedix, Inc. High sensitivity amperometric biosensor with side-to-side hybrid configuration
DE602004029092D1 (en) 2003-12-05 2010-10-21 Dexcom Inc CALIBRATION METHODS FOR A CONTINUOUSLY WORKING ANALYTIC SENSOR
US7282705B2 (en) 2003-12-19 2007-10-16 Agilent Technologies, Inc. Microdevice having an annular lining for producing an electrospray emitter
US20050197548A1 (en) 2004-03-05 2005-09-08 Elekon Industries Usa, Inc. Disposable/reusable flexible sensor
AU2004318179B2 (en) 2004-03-05 2009-07-23 Egomedical Swiss Ag Analyte test system for determining the concentration of an analyte in a physiological fluid
US7322942B2 (en) * 2004-05-07 2008-01-29 Roche Diagnostics Operations, Inc. Integrated disposable for automatic or manual blood dosing
US7299081B2 (en) 2004-06-15 2007-11-20 Abbott Laboratories Analyte test device
US7727166B2 (en) 2004-07-26 2010-06-01 Nova Biomedical Corporation Lancet, lancet assembly and lancet-sensor combination
US9002473B2 (en) * 2004-10-29 2015-04-07 Koninklijke Philips N.V. Electrode and enclosure for cardiac monitoring and treatment
DE102004060742A1 (en) 2004-12-15 2006-07-06 Albert-Ludwig-Universität Freiburg Micro-sensor for determining bodily fluid contents, comprises a conical shape and comprises a micro-electrode with fibers, one of which is a working electrode with a layer of an electro-active polymer
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20060289704A1 (en) 2005-06-28 2006-12-28 Siemens Medical Solutions Usa, Inc. Adjustable support mechanism for a flat-panel display
US7725148B2 (en) 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes
US8057404B2 (en) * 2005-10-12 2011-11-15 Panasonic Corporation Blood sensor, blood testing apparatus, and method for controlling blood testing apparatus
EP1939613A4 (en) 2005-10-17 2013-09-04 Sumitomo Electric Industries Sensor chip and method for producing the same
US8105244B2 (en) * 2005-11-30 2012-01-31 Abbott Diabetes Care Inc. Integrated sensor for analyzing biological samples
US7922971B2 (en) * 2005-11-30 2011-04-12 Abbott Diabetes Care Inc. Integrated meter for analyzing biological samples
GB0526051D0 (en) * 2005-12-21 2006-02-01 Oxford Biosensors Ltd Cholesterol sensor
JP4802737B2 (en) 2006-01-31 2011-10-26 パナソニック株式会社 Chemical solution administration device and control method thereof
US7811430B2 (en) * 2006-02-28 2010-10-12 Abbott Diabetes Care Inc. Biosensors and methods of making
US7695601B2 (en) 2006-05-09 2010-04-13 The United States Of America As Represented By The Secretary Of The Army Electrochemical test apparatus and method for its use
US8944276B2 (en) 2006-06-06 2015-02-03 Tony Garagiola Dumpster with a moveable false floor and method of collecting trash using the same
ATE493645T1 (en) * 2006-08-08 2011-01-15 Hoffmann La Roche ELECTROCHEMICAL SENSOR FOR DETERMINING AN ANALYTE CONCENTRATION
US20090032760A1 (en) 2006-10-23 2009-02-05 Ralph Muscatell Rotational multi vane positive displacement valve for use with a solar air conditioning system
CA2681412A1 (en) 2007-03-26 2008-10-02 Dexcom, Inc. Analyte sensor
US20120046533A1 (en) 2007-08-29 2012-02-23 Medtronic Minimed, Inc. Combined sensor and infusion sets
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
US9044178B2 (en) * 2007-08-30 2015-06-02 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
WO2009032760A2 (en) 2007-08-30 2009-03-12 Pepex Biomedical Llc Electrochmical sensor and method for manufacturing
EP2341830A4 (en) 2008-09-19 2012-10-31 Bayer Healthcare Llc Analyte sensors, systems, testing apparatus and manufacturing methods
CA2735606A1 (en) 2008-09-19 2010-03-25 Bayer Healthcare Llc Lancet analyte sensors and methods of manufacturing
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
US8506740B2 (en) 2008-11-14 2013-08-13 Pepex Biomedical, Llc Manufacturing electrochemical sensor module
US20110266149A1 (en) 2008-11-14 2011-11-03 Pepex Biomedical, Llc Electrochemical sensor module
US8298158B2 (en) 2009-06-30 2012-10-30 Abbott Diabetes Care Inc. Integrated devices having extruded electrode structures and methods of using same
US20110024043A1 (en) * 2009-07-02 2011-02-03 Dexcom, Inc. Continuous analyte sensors and methods of making same
JP5758606B2 (en) 2010-09-30 2015-08-05 テルモ株式会社 Component measuring apparatus and component measuring apparatus manufacturing method
AU2012212655B2 (en) 2011-01-06 2015-12-24 Pepex Biomedical, Inc. Sensor module with enhanced capillary flow
WO2014025430A2 (en) 2012-05-10 2014-02-13 The Regents Of The University Of California Wearable electrochemical sensors
WO2014089058A1 (en) 2012-12-03 2014-06-12 Pepex Biomedical, Inc. Sensor module and method of using a sensor module
CN104116513A (en) 2013-04-23 2014-10-29 马荣华 Self-priming type quantitative micro-quantity blood collection tube

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989007139A1 (en) * 1988-02-05 1989-08-10 Novo-Nordisk A/S A method for immobilizing a polypeptide in a polymer and a membrane produced thereby
WO1991015993A1 (en) * 1990-04-19 1991-10-31 The University Of Kansas Implantable glucose sensor
EP0965301A1 (en) * 1998-06-11 1999-12-22 Matsushita Electric Industrial Co., Ltd. Electrode probe and body fluid examination equipment including the same
US6464849B1 (en) * 1999-10-07 2002-10-15 Pepex Biomedical, L.L.C. Sensor for measuring a bioanalyte such as lactate
US6965791B1 (en) * 2003-03-26 2005-11-15 Sorenson Medical, Inc. Implantable biosensor system, apparatus and method
WO2005051183A1 (en) * 2003-11-25 2005-06-09 Novo Nordisk A/S A needle sensor and a mechanism for inserting the needle sensor through the skin
WO2007091633A1 (en) * 2006-02-09 2007-08-16 The University Of Tokushima Biodevice, contact part structure of biodevice, and biosensor
EP2023134A1 (en) * 2006-02-09 2009-02-11 The University of Tokushima Biodevice, contact part structure of biodevice, and biosensor

Also Published As

Publication number Publication date
US9459228B2 (en) 2016-10-04
US20110189762A1 (en) 2011-08-04
US11150212B2 (en) 2021-10-19
US8702932B2 (en) 2014-04-22
US20170067845A1 (en) 2017-03-09
US20140318988A1 (en) 2014-10-30
WO2009032760A2 (en) 2009-03-12

Similar Documents

Publication Publication Date Title
WO2009032760A3 (en) Electrochmical sensor and method for manufacturing
EP2203725A4 (en) Method and assembly for determining the temperature of a test sensor
EP2224159A4 (en) Vacuum heat insulation material and manufacturing method therefor
HK1130088A1 (en) Amperometric sensor and method for its manufacturing
EP1840545B8 (en) Torque sensor and method of manufacturing the same
GB0810318D0 (en) Solid state electrochemical gas sensor and method for fabricating same
EP1671375A4 (en) Bolometric infrared sensor having two layer structure and method for manufacturing the same
WO2012044001A3 (en) Vacuum insulation panel, refrigerator with vacuum insulation panel and manufacturing method for vacuum insulation panel
EP2402778A4 (en) Magnetoimpedance sensor element and method for manufacturing the same
PL2408609T3 (en) Method and device for the automated manufacture of at least one elongate composite material part with one or more layers
HK1113948A1 (en) Micro-mechanical part made of insulating material and method of manufacturing the same
GB2479293B (en) Sintered metal oxide for thermistor, thermistor element, thermistor temperature sensor, and method for producing sintered metal oxide for thermistor
EP2412685A3 (en) Thermochromic smart window and method of manufacturing the same
EP1887331A4 (en) Infrared sensor and its manufacturing process
EP2381232A4 (en) Precise critical temperature indicator and manufacturing method thereof
WO2010027604A3 (en) Extruded housing for hand-held device with a cap for covering two or more adjacent sides
EP2324344A4 (en) Improved capacitive sensor and method for making the same
WO2010078189A3 (en) Flash cell with integrated high-k dielectric and metal-based control gate
EP2177491A4 (en) Metal oxide sintered body for thermistor, thermistor element, thermistor temperature sensor, and method for producing metal oxide sintered body for thermistor
PL1972516T3 (en) Method and servomotor designed to detect the braking of a vehicle and method of manufacturing such a servomotor
WO2009000671A3 (en) Heat-insulating wall for a refrigerating device
IL299685A (en) Analyte sensor and its manufacturing
WO2011011612A3 (en) Wired conduit segment and method of making same
WO2011117633A3 (en) Consumable biscuit products and methods of production thereof
EP2052265A4 (en) Circuit for continuously measuring discontinuous metal insulator transition of mit element and mit sensor using the same

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08829247

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08829247

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 12674858

Country of ref document: US