WO2008127438A3 - Parallel flow control (pfc) approach for active control, characterization, and manipulation of nanofluidics - Google Patents

Parallel flow control (pfc) approach for active control, characterization, and manipulation of nanofluidics Download PDF

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Publication number
WO2008127438A3
WO2008127438A3 PCT/US2007/085630 US2007085630W WO2008127438A3 WO 2008127438 A3 WO2008127438 A3 WO 2008127438A3 US 2007085630 W US2007085630 W US 2007085630W WO 2008127438 A3 WO2008127438 A3 WO 2008127438A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanofluidic
channel
pressure
microfluidic channel
parallel
Prior art date
Application number
PCT/US2007/085630
Other languages
French (fr)
Other versions
WO2008127438A2 (en
Inventor
Stephen J Fonash
Wook Jun Nam
Huinan Liang
Original Assignee
Penn State Res Found
Stephen J Fonash
Wook Jun Nam
Huinan Liang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Res Found, Stephen J Fonash, Wook Jun Nam, Huinan Liang filed Critical Penn State Res Found
Publication of WO2008127438A2 publication Critical patent/WO2008127438A2/en
Publication of WO2008127438A3 publication Critical patent/WO2008127438A3/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/088—Channel loops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Abstract

A method of active nanofluidic flow control (parallel flow control-PFC) includes providing a nanofluidic channel and a pressure-driven microfluidic channel connected in parallel and actively controlling flow through the nanofluidic channel by using the pressure-driven microfluidic channel. A method of nanofluidic flow measurement includes providing a nanofluidic channel, a pressure-driven microfluidic channel connected in parallel for flow control, and an additional measurement microfluidic channel connected in series for flow measurement and measuring the nanofluidic flow rate by measuring the filling rate in the measurement microfluidic channel. A method of nano-scale volume fluid manipulation includes providing a nanofluidic channel and a pressure-driven microfluidic channel connected in parallel and manipulating nano-scale volume fluid through the nanofluidic channel by using the pressure-driven microfluidic channel. A method of fabricating a fluidic system is provided. The method includes forming a nanofluidic channel and a pressure-driven microfluidic channel connected to the nanofluidic channel in parallel.
PCT/US2007/085630 2006-11-27 2007-11-27 Parallel flow control (pfc) approach for active control, characterization, and manipulation of nanofluidics WO2008127438A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86729306P 2006-11-27 2006-11-27
US60/867,293 2006-11-27

Publications (2)

Publication Number Publication Date
WO2008127438A2 WO2008127438A2 (en) 2008-10-23
WO2008127438A3 true WO2008127438A3 (en) 2008-12-24

Family

ID=39864554

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/085630 WO2008127438A2 (en) 2006-11-27 2007-11-27 Parallel flow control (pfc) approach for active control, characterization, and manipulation of nanofluidics

Country Status (1)

Country Link
WO (1) WO2008127438A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105129722A (en) * 2015-07-01 2015-12-09 北京工业大学 Fabrication method for micro channel of single-sided micro-order thin film
CN108855256B (en) * 2018-04-25 2020-06-02 南开大学 Microfluidic chip and method for detecting deformability of red blood cells
CN110975953B (en) * 2019-12-14 2021-08-24 深圳先进技术研究院 Micro-nano fluidic chip and preparation method and application thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8435415B2 (en) 2009-11-24 2013-05-07 The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology Nanofabrication process and nanodevice
US8438903B2 (en) 2010-01-27 2013-05-14 International Business Machines Corporation Molecule detection device formed in a semiconductor structure
WO2018060263A1 (en) * 2016-09-30 2018-04-05 Wageningen Universiteit Nanofluidic device, fluidic system and method for performing a test
US10046322B1 (en) 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
CN112652842B (en) * 2020-12-18 2024-01-26 武汉轻工大学 Microfluidic photocatalytic fuel cell and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030136679A1 (en) * 2001-10-18 2003-07-24 The Board Of Trustees Of The University Of Illinois Hybrid microfluidic and nanofluidic system
US20030230486A1 (en) * 2002-03-05 2003-12-18 Caliper Technologies Corp. Mixed mode microfluidic systems

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030136679A1 (en) * 2001-10-18 2003-07-24 The Board Of Trustees Of The University Of Illinois Hybrid microfluidic and nanofluidic system
US20030230486A1 (en) * 2002-03-05 2003-12-18 Caliper Technologies Corp. Mixed mode microfluidic systems

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105129722A (en) * 2015-07-01 2015-12-09 北京工业大学 Fabrication method for micro channel of single-sided micro-order thin film
CN108855256B (en) * 2018-04-25 2020-06-02 南开大学 Microfluidic chip and method for detecting deformability of red blood cells
CN110975953B (en) * 2019-12-14 2021-08-24 深圳先进技术研究院 Micro-nano fluidic chip and preparation method and application thereof

Also Published As

Publication number Publication date
WO2008127438A2 (en) 2008-10-23

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