WO2008112135A3 - Method and aparatus for spectroscopic tissue analyte measurement - Google Patents

Method and aparatus for spectroscopic tissue analyte measurement Download PDF

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Publication number
WO2008112135A3
WO2008112135A3 PCT/US2008/003014 US2008003014W WO2008112135A3 WO 2008112135 A3 WO2008112135 A3 WO 2008112135A3 US 2008003014 W US2008003014 W US 2008003014W WO 2008112135 A3 WO2008112135 A3 WO 2008112135A3
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WO
WIPO (PCT)
Prior art keywords
tissue
subject
body fluid
linear regression
calculating
Prior art date
Application number
PCT/US2008/003014
Other languages
French (fr)
Other versions
WO2008112135A2 (en
Inventor
Jr Clark R Baker
Nicholas J Durr
Murtaza Mogri
Carine Hoarau
Rafael Ostrowski
Martin P Debreczeny
Original Assignee
Nellcor Puritan Bennett Llc
Jr Clark R Baker
Nicholas J Durr
Murtaza Mogri
Carine Hoarau
Rafael Ostrowski
Martin P Debreczeny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nellcor Puritan Bennett Llc, Jr Clark R Baker, Nicholas J Durr, Murtaza Mogri, Carine Hoarau, Rafael Ostrowski, Martin P Debreczeny filed Critical Nellcor Puritan Bennett Llc
Publication of WO2008112135A2 publication Critical patent/WO2008112135A2/en
Publication of WO2008112135A3 publication Critical patent/WO2008112135A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A61B5/4875—Hydration status, fluid retention of the body
    • A61B5/4878—Evaluating oedema

Abstract

Methods and systems for calculating body fluid metrics are provided. In accordance with an exemplary embodiment of the present technique, there is provided a method (50) for calculating body fluid metrics by acquiring an absorbance spectrum of a subject's tissue over a range of near-infrared light (56), performing a multi-linear regression of the absorbance spectrum of the subject's tissue in relation to absorbance spectra of tissue constituents (60), and calculating body fluid metrics based on the results of the multi-linear regression (66). A system (20) is provided having a sensor (24) for emitting the light into the subject's tissue and detecting reflected, scattered, or transmitted light, a spectrometer (40) for processing the detected light and generating the absorbance spectrum of the subject's tissue, memory (44) for storing absorbance spectra of the tissue constituents and a multi-linear regression model, and a processor (42) for performing the multi-linear regression and calculating the body fluid metrics.
PCT/US2008/003014 2007-03-09 2008-03-06 Method and aparatus for spectroscopic tissue analyte measurement WO2008112135A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/716,482 2007-03-09
US11/716,482 US8175665B2 (en) 2007-03-09 2007-03-09 Method and apparatus for spectroscopic tissue analyte measurement

Publications (2)

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WO2008112135A2 WO2008112135A2 (en) 2008-09-18
WO2008112135A3 true WO2008112135A3 (en) 2008-11-27

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PCT/US2008/003014 WO2008112135A2 (en) 2007-03-09 2008-03-06 Method and aparatus for spectroscopic tissue analyte measurement

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US (1) US8175665B2 (en)
WO (1) WO2008112135A2 (en)

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US20080221412A1 (en) 2008-09-11
WO2008112135A2 (en) 2008-09-18

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