WO2008093347A3 - Method for preparing particles comprising metal oxide coating and particles with metal oxide coating - Google Patents

Method for preparing particles comprising metal oxide coating and particles with metal oxide coating Download PDF

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Publication number
WO2008093347A3
WO2008093347A3 PCT/IL2008/000141 IL2008000141W WO2008093347A3 WO 2008093347 A3 WO2008093347 A3 WO 2008093347A3 IL 2008000141 W IL2008000141 W IL 2008000141W WO 2008093347 A3 WO2008093347 A3 WO 2008093347A3
Authority
WO
WIPO (PCT)
Prior art keywords
metal oxide
particles
particulate matter
oxide coating
coating
Prior art date
Application number
PCT/IL2008/000141
Other languages
French (fr)
Other versions
WO2008093347A2 (en
Inventor
Ofer Toledano
Haim Bar-Simantov
Nissim Bilman
Leora Shapiro
Raed Abu-Reziq
Srikanth Sriadibhatla
William T. Sommer
Original Assignee
Sol-Gel Technologies Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP08702720.7A priority Critical patent/EP2118208B1/en
Priority to AU2008211554A priority patent/AU2008211554B2/en
Application filed by Sol-Gel Technologies Ltd. filed Critical Sol-Gel Technologies Ltd.
Priority to MX2009008256A priority patent/MX352876B/en
Priority to US12/525,331 priority patent/US20100016443A1/en
Priority to BRPI0808160-3A priority patent/BRPI0808160A2/en
Priority to EA200970725A priority patent/EA018275B1/en
Priority to CN2008800075142A priority patent/CN101754677B/en
Priority to JP2009547811A priority patent/JP5382723B2/en
Priority to CA2677185A priority patent/CA2677185C/en
Priority to ES08702720T priority patent/ES2763829T3/en
Publication of WO2008093347A2 publication Critical patent/WO2008093347A2/en
Priority to IL200175A priority patent/IL200175A0/en
Priority to ZA2009/05365A priority patent/ZA200905365B/en
Publication of WO2008093347A3 publication Critical patent/WO2008093347A3/en
Priority to US17/002,266 priority patent/US20200383927A1/en
Priority to US17/016,528 priority patent/US20210007996A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38—Percompounds, e.g. peracids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09C—TREATMENT OF INORGANIC MATERIALS, OTHER THAN FIBROUS FILLERS, TO ENHANCE THEIR PIGMENTING OR FILLING PROPERTIES ; PREPARATION OF CARBON BLACK  ; PREPARATION OF INORGANIC MATERIALS WHICH ARE NO SINGLE CHEMICAL COMPOUNDS AND WHICH ARE MAINLY USED AS PIGMENTS OR FILLERS
    • C09C3/00—Treatment in general of inorganic materials, other than fibrous fillers, to enhance their pigmenting or filling properties
    • C09C3/06—Treatment with inorganic compounds
    • C09C3/063—Coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated

Abstract

The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.
PCT/IL2008/000141 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating WO2008093347A2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
CA2677185A CA2677185C (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
JP2009547811A JP5382723B2 (en) 2007-02-01 2008-02-03 Method for producing particles comprising a metal oxide coating and particles having a metal oxide coating
MX2009008256A MX352876B (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating.
AU2008211554A AU2008211554B2 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
BRPI0808160-3A BRPI0808160A2 (en) 2007-02-01 2008-02-03 PROCESS FOR COATING A SOLID, WATER-INSOLATED PRIVATE MATERIAL WITH A METAL OXIDE, COATED PARTICULATED MATERIALS, METHODS TO TREAT A SURFACE CONDITION ON AN INDIVIDUAL, AND TO PREVENT, REDUCE, OR ELIMINATE, OR ELIMINATE, USE OF COATED PRIVATE MATERIAL
EA200970725A EA018275B1 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
ES08702720T ES2763829T3 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising a metal oxide coating
EP08702720.7A EP2118208B1 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating
US12/525,331 US20100016443A1 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
CN2008800075142A CN101754677B (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
IL200175A IL200175A0 (en) 2007-02-01 2009-07-30 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
ZA2009/05365A ZA200905365B (en) 2007-02-01 2009-07-31 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
US17/002,266 US20200383927A1 (en) 2007-02-01 2020-08-25 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
US17/016,528 US20210007996A1 (en) 2007-02-01 2020-09-10 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89870007P 2007-02-01 2007-02-01
US60/898,700 2007-02-01

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/525,331 A-371-Of-International US20100016443A1 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating
US17/002,266 Division US20200383927A1 (en) 2007-02-01 2020-08-25 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating

Publications (2)

Publication Number Publication Date
WO2008093347A2 WO2008093347A2 (en) 2008-08-07
WO2008093347A3 true WO2008093347A3 (en) 2009-10-22

Family

ID=39674593

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2008/000141 WO2008093347A2 (en) 2007-02-01 2008-02-03 Method for preparing particles comprising metal oxide coating and particles with metal oxide coating

Country Status (13)

Country Link
US (3) US20100016443A1 (en)
EP (2) EP2118208B1 (en)
JP (1) JP5382723B2 (en)
KR (1) KR20090121291A (en)
CN (1) CN101754677B (en)
AU (1) AU2008211554B2 (en)
BR (1) BRPI0808160A2 (en)
CA (2) CA2824842C (en)
EA (1) EA018275B1 (en)
ES (1) ES2763829T3 (en)
MX (1) MX352876B (en)
WO (1) WO2008093347A2 (en)
ZA (1) ZA200905365B (en)

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