WO2008060142A1 - Method for making a catheter - Google Patents

Method for making a catheter Download PDF

Info

Publication number
WO2008060142A1
WO2008060142A1 PCT/NL2007/000282 NL2007000282W WO2008060142A1 WO 2008060142 A1 WO2008060142 A1 WO 2008060142A1 NL 2007000282 W NL2007000282 W NL 2007000282W WO 2008060142 A1 WO2008060142 A1 WO 2008060142A1
Authority
WO
WIPO (PCT)
Prior art keywords
electrode
housing
basic body
mould
electrode housing
Prior art date
Application number
PCT/NL2007/000282
Other languages
French (fr)
Inventor
Gheorghe Aurel Marie Pop
Original Assignee
Martil Instruments B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martil Instruments B.V. filed Critical Martil Instruments B.V.
Publication of WO2008060142A1 publication Critical patent/WO2008060142A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode

Definitions

  • the invention relates to a method for making a catheter and a catheter made with this method.
  • It relates particularly to a catheter with one or more electrodes at the distal end.
  • An electric connecting line of each of these electrodes which are for instance annular, must be led from the tip of the catheter through the basic body and to the proximal end.
  • the connection of this line to the electrode is very difficult from a production engineering viewpoint.
  • a stripped end of the electrical conductor is first pulled outward from inside, for instance from a lumen, and a number of winds are laid on the bottom of a groove in a part of the catheter.
  • An annular electrode is then crimped into this groove at this position, so creating an electrical connection in that the material of the electrode makes contact with the material of the electrical conductor.
  • the sides of the ring must then be sealed in order to prevent material, such as liquids, being able to penetrate under the electrode ring.
  • the invention now relates to a method for making a catheter as specified above which can be performed more efficiently.
  • an electrode housing is provided for the catheter, which housing comprises a prismatic part in the surface of which a number of grooves is formed.
  • the electrical conductor of an electrode is connected to this latter by welding or soldering a short, stripped part fixedly to an inner surface of the electrode.
  • the conductor extends here in axial direction relative to the electrode.
  • the electrode which can for instance be annular, can then slide onto the housing, wherein the conductor slides through one of the grooves of the housing.
  • a plurality of electrodes are applied they can slide successively onto the electrode housing, wherein a different groove is chosen in each case for the relevant conductor.
  • the first electrode is pushed furthest onto the housing, and the subsequent ones slightly less far in each case.
  • the dimensioning is preferably chosen such that the electrodes slide onto the housing with a certain frictional resistance and thus retain their position once it has been set.
  • the housing with the electrodes thereon is arranged in a mould.
  • the mould cavity is here preferably such that the periphery of the electrodes comes into contact with the wall of the mould cavity.
  • a suitable flexible plastic such as for instance polyurethane or a mixture containing polyurethane, is then injected into the mould cavity.
  • a layer of this plastic, with an outer diameter the same as that of the electrodes, is hereby arranged round the housing.
  • the outer surface of the electrodes herein remains free of plastic and the electrodes can thus continue to fulfil their intended function.
  • the thus obtained end part for a catheter can then be attached to a basic body of a catheter in more or less known manner, for instance by glueing.
  • the one or more conductors are herein received in one or more lumina of the basic body.
  • the transition from the catheter tip to the basic body is finished in usual manner such that a smooth transition is obtained.
  • the catheter housing can comprise a transition part connecting to the prismatic part, wherein the grooves for instance taper gradually toward the end to one position coinciding with the position of a lumen in the basic body.
  • One or more lumina can also be formed in the electrode housing which are brought into connection with corresponding lumina in the basic body in a uniform manner via the transition part. A liquid can for instance be supplied via these lumina .
  • the electrode housing with the one or more electrodes arranged thereon is arranged against the end of the basic body before the injection moulding process.
  • the conductors are received for this purpose in the lumina arranged for the purpose in the basic body, and the basic body is pushed against the housing over these conductors.
  • the catheter housing and the end part of the catheter lying thereagainst are then arranged in a suitable mould, which has a mould cavity which fits closely onto the periphery of the basic body of the catheter and onto the periphery of the electrode.
  • the remaining mould space is then filled by injection with a suitable plastic, which provides for the finishing of the catheter end to a fully prismatic part and the connection of the housing to the end of the basic body.
  • the catheter and housing comprise one or more lumina, they can be temporarily filled with a core pin during the injection moulding process in order to prevent the plastic penetrating these lumina.
  • annular electrodes are recommended, the method and the catheter are not limited to embodiments with such annular electrodes.
  • the electrodes can for instance be shell-like and be provided with inward protruding profile parts which engage in two opposite grooves in the electrode housing. An electrode can thus be applied with an electrode surface which is effective only over a portion of the periphery.
  • annular electrode it is also possible in such a case to use an annular electrode but to have the outer surface thereof recessed to some extent over part of the periphery, whereby after the injection moulding a layer of the injected plastic will come to lie over this recessed part and only the other part of the electrode thus remains free .
  • the mould can be suitably dimensioned such that the mould cavity clampingly encloses the electrodes.
  • Another option is to arrange positioning elements in the mould which are formed for instance by shell-like magnets in each of the mould halves, which shell-like magnets form rings in the closed form of the mould.
  • the electrode rings can in this way be properly fixed in the mould.
  • Figure 1 shows a perspective view with cut-away parts of an end part of a catheter made with the method according to the invention.
  • Figure 2 shows a view with exploded parts of the end part of figure 1.
  • Catheter 1 comprises a basic body 2, only a very small portion of which is shown. At the left-hand end seen in figure 1 the basic body extends further over a considerable length to the proximal end of the catheter.
  • Numeral 3 designates the tip part.
  • this comprises an electrode housing 4 on which four electrodes 6, 7, 8, 9 are arranged.
  • each of these electrodes 6-9 is connected to a respective conductor 11-14.
  • the relevant conductor is stripped at its end, i.e. stripped of insulating material and connected by welding or soldering to the inside of the annular electrode.
  • Electrodes 6-9 are then pushed onto electrode housing 4.
  • This electrode housing 4 comprises a prismatic part which is provided with a number of grooves 15 for receiving in each case one of the conductors 11-14. It will be apparent that the most distal electrode, in this case 9, is pushed first onto housing 4, followed by 8 adjacently thereof and then 7 and 6.
  • the dimensioning of the electrode housing and the electrodes is preferably such that the annular electrodes can slide over electrode housing 4 with a light clamp fit, or in any case with a certain resistance, so that once they have been placed in their position they remain there.
  • a small ridge can optionally be formed on the inner side of the electrode and can fall into a groove formed in the housing.
  • the thus formed assembly of electrode housing with electrodes and conductors connected thereto is arranged in an injection mould, into which is then injected a suitable plastic which fills the contour up to the contour indicated with line 5 in figure 1.
  • the electrode housing can co-act or be formed integrally with a transition part 14, in which are formed lumina 17, 18 which connect between the lumina in the basic body and those in the housing. It is also possible to insert the conductors directly into the lumina in basic body 2 intended for the purpose and to incorporate in lumen 16 of the basic body a core wire which extends through lumen 20 in electrode housing 4. This assembly can then be arranged in a mould, wherein the mould cavity is filled with a suitable plastic. Transition part 14 is thus then formed in the same injection moulding operation as the filling between the electrodes. The core wire can be removed after the plastic solidifies, thereby forming the continuous lumen . Not shown in the figures is that a soft, moulded-on tip can also be situated, at the most distal end of the catheter. This is however a per se usual provision.

Abstract

Method for making a catheter, comprising of providing an electrode housing which comprises a prismatic part in the surface of which a number of grooves is formed, providing at least one electrode, connecting an electrical conductor to each electrode, wherein the electrical conductor extends in axial direction relative to the electrode, sliding each electrode onto the electrode housing, wherein the electrical conductor thereof slides through one of the grooves of the housing, positioning the electrode on the electrode housing, arranging the electrode housing with the electrode thereon in a mould cavity of a mould; and arranging round the electrode housing a layer of plastic with an outer diameter substantially the same as that of the electrode.

Description

METHOD FOR MAKING A CATHETER
The invention relates to a method for making a catheter and a catheter made with this method.
It relates particularly to a catheter with one or more electrodes at the distal end. An electric connecting line of each of these electrodes, which are for instance annular, must be led from the tip of the catheter through the basic body and to the proximal end. The connection of this line to the electrode is very difficult from a production engineering viewpoint. In a known method a stripped end of the electrical conductor is first pulled outward from inside, for instance from a lumen, and a number of winds are laid on the bottom of a groove in a part of the catheter. An annular electrode is then crimped into this groove at this position, so creating an electrical connection in that the material of the electrode makes contact with the material of the electrical conductor. The sides of the ring must then be sealed in order to prevent material, such as liquids, being able to penetrate under the electrode ring.
It will be apparent that such a manufacturing method almost wholly entails manual work and is time- consuming and therefore expensive. Particularly when a number of electrode rings, such as for instance four, must be arranged on a catheter with a small diameter, the manufacturing method requires great accuracy and skill from the manufacturing personnel.
The invention now relates to a method for making a catheter as specified above which can be performed more efficiently.
For this purpose an electrode housing is provided for the catheter, which housing comprises a prismatic part in the surface of which a number of grooves is formed.
The electrical conductor of an electrode is connected to this latter by welding or soldering a short, stripped part fixedly to an inner surface of the electrode. The conductor extends here in axial direction relative to the electrode.
The electrode, which can for instance be annular, can then slide onto the housing, wherein the conductor slides through one of the grooves of the housing.
If a plurality of electrodes are applied they can slide successively onto the electrode housing, wherein a different groove is chosen in each case for the relevant conductor. The first electrode is pushed furthest onto the housing, and the subsequent ones slightly less far in each case.
The dimensioning is preferably chosen such that the electrodes slide onto the housing with a certain frictional resistance and thus retain their position once it has been set.
When the electrode or electrodes are thus arranged in their mutually correct positions on the electrode housing, the housing with the electrodes thereon is arranged in a mould. The mould cavity is here preferably such that the periphery of the electrodes comes into contact with the wall of the mould cavity. A suitable flexible plastic, such as for instance polyurethane or a mixture containing polyurethane, is then injected into the mould cavity. A layer of this plastic, with an outer diameter the same as that of the electrodes, is hereby arranged round the housing. The outer surface of the electrodes herein remains free of plastic and the electrodes can thus continue to fulfil their intended function. The thus obtained end part for a catheter can then be attached to a basic body of a catheter in more or less known manner, for instance by glueing. The one or more conductors are herein received in one or more lumina of the basic body. The transition from the catheter tip to the basic body is finished in usual manner such that a smooth transition is obtained. In suitable manner the catheter housing can comprise a transition part connecting to the prismatic part, wherein the grooves for instance taper gradually toward the end to one position coinciding with the position of a lumen in the basic body. One or more lumina can also be formed in the electrode housing which are brought into connection with corresponding lumina in the basic body in a uniform manner via the transition part. A liquid can for instance be supplied via these lumina .
In another further developed manufacturing method the electrode housing with the one or more electrodes arranged thereon is arranged against the end of the basic body before the injection moulding process. The conductors are received for this purpose in the lumina arranged for the purpose in the basic body, and the basic body is pushed against the housing over these conductors.
The catheter housing and the end part of the catheter lying thereagainst are then arranged in a suitable mould, which has a mould cavity which fits closely onto the periphery of the basic body of the catheter and onto the periphery of the electrode. The remaining mould space is then filled by injection with a suitable plastic, which provides for the finishing of the catheter end to a fully prismatic part and the connection of the housing to the end of the basic body. In the case the catheter and housing comprise one or more lumina, they can be temporarily filled with a core pin during the injection moulding process in order to prevent the plastic penetrating these lumina. It is not a problem for the plastic to penetrate into the grooves and lumina in which the conductors extend, since these conductors are hereby fixed very- well and this only enhances the strength of the connections . In the same injection moulding process a soft tip can be moulded onto the other end of the electrode housing, for instance by in situ injection of plastic of a suitable different composition.
Although annular electrodes are recommended, the method and the catheter are not limited to embodiments with such annular electrodes. The electrodes can for instance be shell-like and be provided with inward protruding profile parts which engage in two opposite grooves in the electrode housing. An electrode can thus be applied with an electrode surface which is effective only over a portion of the periphery.
It is also possible in such a case to use an annular electrode but to have the outer surface thereof recessed to some extent over part of the periphery, whereby after the injection moulding a layer of the injected plastic will come to lie over this recessed part and only the other part of the electrode thus remains free .
In order to prevent displacement of the electrode in the mould during the injection moulding process, the mould can be suitably dimensioned such that the mould cavity clampingly encloses the electrodes. Another option is to arrange positioning elements in the mould which are formed for instance by shell-like magnets in each of the mould halves, which shell-like magnets form rings in the closed form of the mould. The electrode rings can in this way be properly fixed in the mould. In order to prevent wear of the mould, it is of course also possible to apply a slightly larger mould cavity instead of a clamp-fitting mould cavity, and to use individually movable pin-like pressing elements. In the closed position of the mould these elements can then press firmly on the annular electrodes so that they cannot displace during the injection moulding. The invention is further elucidated in the following description with reference to the accompanying figures .
Figure 1 shows a perspective view with cut-away parts of an end part of a catheter made with the method according to the invention.
Figure 2 shows a view with exploded parts of the end part of figure 1.
Catheter 1 comprises a basic body 2, only a very small portion of which is shown. At the left-hand end seen in figure 1 the basic body extends further over a considerable length to the proximal end of the catheter.
Numeral 3 designates the tip part. In this embodiment this comprises an electrode housing 4 on which four electrodes 6, 7, 8, 9 are arranged. As shown in figure 2, each of these electrodes 6-9 is connected to a respective conductor 11-14. For this purpose the relevant conductor is stripped at its end, i.e. stripped of insulating material and connected by welding or soldering to the inside of the annular electrode.
Electrodes 6-9 are then pushed onto electrode housing 4. This electrode housing 4 comprises a prismatic part which is provided with a number of grooves 15 for receiving in each case one of the conductors 11-14. It will be apparent that the most distal electrode, in this case 9, is pushed first onto housing 4, followed by 8 adjacently thereof and then 7 and 6. The dimensioning of the electrode housing and the electrodes is preferably such that the annular electrodes can slide over electrode housing 4 with a light clamp fit, or in any case with a certain resistance, so that once they have been placed in their position they remain there.
In order to ensure an accurate position of the electrode relative to housing 4, a small ridge can optionally be formed on the inner side of the electrode and can fall into a groove formed in the housing. In a subsequent method step the thus formed assembly of electrode housing with electrodes and conductors connected thereto is arranged in an injection mould, into which is then injected a suitable plastic which fills the contour up to the contour indicated with line 5 in figure 1.
The electrode housing can co-act or be formed integrally with a transition part 14, in which are formed lumina 17, 18 which connect between the lumina in the basic body and those in the housing. It is also possible to insert the conductors directly into the lumina in basic body 2 intended for the purpose and to incorporate in lumen 16 of the basic body a core wire which extends through lumen 20 in electrode housing 4. This assembly can then be arranged in a mould, wherein the mould cavity is filled with a suitable plastic. Transition part 14 is thus then formed in the same injection moulding operation as the filling between the electrodes. The core wire can be removed after the plastic solidifies, thereby forming the continuous lumen . Not shown in the figures is that a soft, moulded-on tip can also be situated, at the most distal end of the catheter. This is however a per se usual provision.

Claims

1. Method for making a catheter, comprising of
- providing an electrode housing which comprises a prismatic part in the surface of which a number of grooves is formed;
- providing at least one electrode;
- connecting an electrical conductor to each electrode, wherein the electrical conductor extends in axial direction relative to the electrode;
-sliding each electrode onto the electrode housing, wherein the electrical conductor thereof slides through one of the grooves of the housing,
- positioning the electrode on the electrode housing; - arranging the electrode housing with the electrode thereon in a mould cavity of a mould;
- arranging round the electrode housing a layer of plastic with an outer diameter substantially the same as that of the electrode.
2. Method as claimed in claim 1, characterized in that the dimensioning of the electrode is such that the electrode slides onto the housing with a certain frictional resistance.
3. Method as claimed in any of the foregoing claims, characterized in that positioning means are arranged on the electrode housing for the purpose of positioning the electrode on the electrode housing.
4. Method as claimed in any of the foregoing claims, characterized in that the electrode is annular.
5. Method as claimed in claim 4, characterized in that the outer surface of the electrode is recessed over a part of the periphery.
6. Method as claimed in any of the claims 1-3, characterized in that the electrode is shell-like and is provided with inward protruding profile parts which engage in two grooves in the electrode housing.
7. Method as claimed in any of the foregoing claims, characterized in that the mould is dimensioned such that the periphery of the electrode comes into contact with the wall of the mould cavity.
8. Method as claimed in claim 7, characterized in that the mould is dimensioned such that the mould cavity clampingly encloses the electrode.
9. Method as claimed in any of the claims 1-6, characterized in that the mould comprises movable pin-like pressing elements.
10. Method as claimed in any of the foregoing claims, characterized in that positioning elements are arranged in the mould.
11. Method as claimed in claim 10, characterized in that the positioning elements comprise shell-like magnets in each half of the mould, which shell-like magnets form rings in the closed form of the mould.
12. Method as claimed in any of the foregoing claims, characterized in that the method also comprises of - providing a basic body with at least one lumen; - receiving the conductors in the lumen of the basic body;
- connecting the electrode housing to the basic body.
13. Method as claimed in claim 12, characterized by connecting the electrode housing to the basic body after the layer of plastic has been arranged round the electrode housing.
14. Method as claimed in claim 12, characterized by arranging the conductors in the lumen of the basic body prior to arranging of the layer of plastic round the electrode housing; wherein - the mould comprises a mould cavity which fits onto the periphery of the basic body and onto the periphery of the electrode; and wherein
- the basic body together with the electrode housing with the electrodes thereon are arranged in the mould.
15. Method as claimed in any of the claims 12-14, characterized in that there is formed in the electrode housing at least one lumen which is brought into connection with a corresponding lumen in the basic body.
16. Method as claimed in claim 15, characterized by filling the lumen in the electrode housing and the corresponding lumen in the basic body with a core pin prior to connecting the electrode housing to the basic body.
17. Method as claimed in any of the claims 12-16, characterized by finishing the transition of the electrode housing to the basic body after connection of the electrode housing to the basic body such that a smooth transition is obtained.
18. Method as claimed in any of the claims 12-17, characterized in that the electrode housing comprises a transition part connecting to the prismatic part, wherein the grooves taper gradually toward the end to one position coinciding with the position of the lumen in the basic body.
19. Method as claimed in any of the foregoing claims, characterized by arranging a soft tip on an end of the electrode housing while the layer of plastic is being arranged round the electrode housing.
20. Method as claimed in any of the foregoing claims, characterized in that connecting of the electrical conductor to the electrode comprises one of fixedly welding and soldering a short stripped portion of the electrical conductor to the inner surface of the electrode.
21. Catheter manufactured with the method as claimed in any of the foregoing claims.
PCT/NL2007/000282 2006-11-13 2007-11-13 Method for making a catheter WO2008060142A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1032858 2006-11-13
NL1032858 2006-11-13

Publications (1)

Publication Number Publication Date
WO2008060142A1 true WO2008060142A1 (en) 2008-05-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2007/000282 WO2008060142A1 (en) 2006-11-13 2007-11-13 Method for making a catheter

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WO (1) WO2008060142A1 (en)

Cited By (10)

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WO2013062863A1 (en) * 2011-10-28 2013-05-02 Medtronic, Inc. Lead end having slotted member
US20130144224A1 (en) * 2010-08-13 2013-06-06 Cathrx Ltd Method of fabricating an electrical lead
US9138576B2 (en) 2011-10-28 2015-09-22 Medtronic, Inc. Lead end having inner support
WO2015187361A1 (en) * 2014-06-07 2015-12-10 Mederi Terapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US9421362B2 (en) 2011-10-28 2016-08-23 Medtronic, Inc. Modular lead end
US9675404B2 (en) 2009-09-22 2017-06-13 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US9750563B2 (en) 2009-09-22 2017-09-05 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
CN107184271A (en) * 2012-05-07 2017-09-22 圣犹达医疗用品电生理部门有限公司 Deflectable catheter axostylus axostyle section and the conduit for including deflectable catheter axostylus axostyle section
US9775664B2 (en) 2009-09-22 2017-10-03 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US11172841B2 (en) 2017-06-21 2021-11-16 Alandra Medical SAPI DE CV Electrode catheter assembly and method for the manufacture thereof

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WO1996018339A1 (en) * 1994-12-14 1996-06-20 Arrow International Investment Corp. Electrode-carrying catheter and method of making
US5855552A (en) * 1994-09-21 1999-01-05 Ep Technologies, Inc. Catheter having ring electrodes secured thereon
WO1999043376A1 (en) * 1998-02-27 1999-09-02 Ep Technologies, Inc. Electrode catheter with bonded surface coatings
US20060142652A1 (en) * 2004-12-28 2006-06-29 Erick Keenan Concepts using the improved "composite flexible and conductive catheter electrode bands" and their method of construction

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US5855552A (en) * 1994-09-21 1999-01-05 Ep Technologies, Inc. Catheter having ring electrodes secured thereon
WO1996018339A1 (en) * 1994-12-14 1996-06-20 Arrow International Investment Corp. Electrode-carrying catheter and method of making
WO1999043376A1 (en) * 1998-02-27 1999-09-02 Ep Technologies, Inc. Electrode catheter with bonded surface coatings
US20060142652A1 (en) * 2004-12-28 2006-06-29 Erick Keenan Concepts using the improved "composite flexible and conductive catheter electrode bands" and their method of construction

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9750563B2 (en) 2009-09-22 2017-09-05 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US11471214B2 (en) 2009-09-22 2022-10-18 Mederi Rf, Llc Systems and methods for treating tissue with radiofrequency energy
US10363089B2 (en) 2009-09-22 2019-07-30 Mederi Rf, Llc Systems and methods for treating tissue with radiofrequency energy
US10292756B2 (en) 2009-09-22 2019-05-21 Mederi Rf, Llc Systems and methods for treating tissue with radiofrequency energy
US9675404B2 (en) 2009-09-22 2017-06-13 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US9775664B2 (en) 2009-09-22 2017-10-03 Mederi Therapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US20130144224A1 (en) * 2010-08-13 2013-06-06 Cathrx Ltd Method of fabricating an electrical lead
US9533119B2 (en) * 2010-08-13 2017-01-03 Cathrx Ltd Method of fabricating an electrical lead
US9421362B2 (en) 2011-10-28 2016-08-23 Medtronic, Inc. Modular lead end
US9713705B2 (en) 2011-10-28 2017-07-25 Medtronic, Inc. Modular lead end
US9962539B2 (en) 2011-10-28 2018-05-08 Medtronic, Inc. Modular lead end
US10076657B2 (en) 2011-10-28 2018-09-18 Medtronic, Inc. Lead end having slotted member
WO2013062863A1 (en) * 2011-10-28 2013-05-02 Medtronic, Inc. Lead end having slotted member
US10413718B2 (en) 2011-10-28 2019-09-17 Medtronic, Inc. Modular lead end
US9138576B2 (en) 2011-10-28 2015-09-22 Medtronic, Inc. Lead end having inner support
CN107184271A (en) * 2012-05-07 2017-09-22 圣犹达医疗用品电生理部门有限公司 Deflectable catheter axostylus axostyle section and the conduit for including deflectable catheter axostylus axostyle section
WO2015187361A1 (en) * 2014-06-07 2015-12-10 Mederi Terapeutics, Inc. Systems and methods for treating tissue with radiofrequency energy
US11172841B2 (en) 2017-06-21 2021-11-16 Alandra Medical SAPI DE CV Electrode catheter assembly and method for the manufacture thereof

Also Published As

Publication number Publication date
NL1034686A1 (en) 2008-05-14
NL1034686C2 (en) 2008-06-17

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