WO2008015645A3 - A method of determining the concentration of an analyte using analyte sensor molecules coupled to a porous membrane - Google Patents

A method of determining the concentration of an analyte using analyte sensor molecules coupled to a porous membrane Download PDF

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Publication number
WO2008015645A3
WO2008015645A3 PCT/IB2007/053031 IB2007053031W WO2008015645A3 WO 2008015645 A3 WO2008015645 A3 WO 2008015645A3 IB 2007053031 W IB2007053031 W IB 2007053031W WO 2008015645 A3 WO2008015645 A3 WO 2008015645A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
concentration
determining
porous membrane
analyte sensor
Prior art date
Application number
PCT/IB2007/053031
Other languages
French (fr)
Other versions
WO2008015645A2 (en
Inventor
Gardiye H P K C Punyadeera
Hendrik R Stapert
Original Assignee
Koninkl Philips Electronics Nv
Gardiye H P K C Punyadeera
Hendrik R Stapert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv, Gardiye H P K C Punyadeera, Hendrik R Stapert filed Critical Koninkl Philips Electronics Nv
Priority to US12/375,769 priority Critical patent/US20090269858A1/en
Priority to BRPI0714653-1A priority patent/BRPI0714653A2/en
Priority to JP2009522405A priority patent/JP2009545739A/en
Publication of WO2008015645A2 publication Critical patent/WO2008015645A2/en
Publication of WO2008015645A3 publication Critical patent/WO2008015645A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

The present invention relates to a method of determining the concentration of an analyte in a sample and/or the binding kinetics of an analyte to an analyte sensor molecule. For this purpose the invention relies on detecting the interaction between the analyte and the analyte sensor molecule with the latter being physically adsorbed to a solid, porous support which is in the form of a micro array. In a preferred embodiment, the method may be operated in repeated cycles.
PCT/IB2007/053031 2006-08-02 2007-08-01 A method of determining the concentration of an analyte using analyte sensor molecules coupled to a porous membrane WO2008015645A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/375,769 US20090269858A1 (en) 2006-08-02 2007-08-01 Method of determining the concentration of an analyte using analyte sensor molecules coupled to a porous membrane
BRPI0714653-1A BRPI0714653A2 (en) 2006-08-02 2007-08-01 Method for detecting at least one analyte in at least one sample
JP2009522405A JP2009545739A (en) 2006-08-02 2007-08-01 Method for determining analyte concentration using analyte sensor molecules bound to a porous membrane

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06118322.4 2006-08-02
EP06118322 2006-08-02

Publications (2)

Publication Number Publication Date
WO2008015645A2 WO2008015645A2 (en) 2008-02-07
WO2008015645A3 true WO2008015645A3 (en) 2008-04-03

Family

ID=38441653

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/053031 WO2008015645A2 (en) 2006-08-02 2007-08-01 A method of determining the concentration of an analyte using analyte sensor molecules coupled to a porous membrane

Country Status (5)

Country Link
US (1) US20090269858A1 (en)
JP (1) JP2009545739A (en)
CN (1) CN101501499A (en)
BR (1) BRPI0714653A2 (en)
WO (1) WO2008015645A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009010563A1 (en) 2009-02-16 2010-08-26 Matthias W. Engel Device for the detection of analytes in body fluids
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
CN103149364A (en) * 2011-12-06 2013-06-12 贵州金玖生物技术有限公司 Protein chip and manufacturing method
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
BR112015004406A2 (en) * 2012-09-04 2017-07-04 Koninklijke Philips Nv sampling method and sensor device
CN105102980B (en) 2013-02-26 2017-11-03 阿斯图特医药公司 Lateral flow assays with strip keeper
US9599615B2 (en) 2013-03-13 2017-03-21 Symbolics, Llc Lateral flow assays using two dimensional test and control signal readout patterns
CA2981297A1 (en) 2015-04-06 2016-10-13 Bludiagnostics, Inc. A test device for detecting an analyte in a saliva sample and method of use
WO2018039047A1 (en) 2016-08-23 2018-03-01 Qoolabs, Inc. Lateral flow assay for assessing recombinant protein expression or reporter gene expression
CN106468712B (en) * 2016-09-26 2018-11-16 海南大学 Based on ochratoxin A method in nano antibody and immune Magneto separate detection cereal
EP3627154A1 (en) 2018-09-20 2020-03-25 Mikrogen GmbH Process for increasing the sensitivity of an immunological test for detecting an antigen in a sample
GB201905181D0 (en) * 2019-04-11 2019-05-29 Arrayjet Ltd Method and apparatus for substrate handling and printing
CN112946253B (en) * 2019-12-11 2022-11-08 广东菲鹏生物有限公司 Treatment agent for solid phase carrier in immunodiagnostic reagent at closed stage, application and product
EP3910336A1 (en) 2020-05-13 2021-11-17 Koninklijke Philips N.V. Lifetime prediction/detection of biomarker sensor
FR3125336B1 (en) * 2021-07-19 2023-07-14 Biomerieux Sa Method for quantifying endotoxins from a biological sample

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197599B1 (en) * 1998-07-30 2001-03-06 Guorong Chin Method to detect proteins
WO2003005013A1 (en) * 2001-07-03 2003-01-16 Georgia Tech Research Corporation Filtration-based microarray chip
WO2003102585A2 (en) * 2002-06-03 2003-12-11 Pamgene B.V. Biomolecular kinetics method using a flow-through microarray
EP1394547A1 (en) * 2002-08-29 2004-03-03 Fuji Photo Film Co., Ltd. Chemical luminescence method using biochemical analysis units
WO2005052583A1 (en) * 2003-11-28 2005-06-09 Olympus Corporation Method of detecting substance to be analyzed

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5038793A (en) * 1989-01-10 1991-08-13 La Mina Ltd. Urine testing membrane module and method of conducting same
US6855539B2 (en) * 1997-07-11 2005-02-15 Pamgene International B.V. Device for performing an assay, a method for manufacturing said device, and use of a membrane in the manufacture of said device
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197599B1 (en) * 1998-07-30 2001-03-06 Guorong Chin Method to detect proteins
WO2003005013A1 (en) * 2001-07-03 2003-01-16 Georgia Tech Research Corporation Filtration-based microarray chip
WO2003102585A2 (en) * 2002-06-03 2003-12-11 Pamgene B.V. Biomolecular kinetics method using a flow-through microarray
EP1394547A1 (en) * 2002-08-29 2004-03-03 Fuji Photo Film Co., Ltd. Chemical luminescence method using biochemical analysis units
WO2005052583A1 (en) * 2003-11-28 2005-06-09 Olympus Corporation Method of detecting substance to be analyzed
EP1693672A1 (en) * 2003-11-28 2006-08-23 Olympus Corporation Method of detecting substance to be analyzed

Also Published As

Publication number Publication date
US20090269858A1 (en) 2009-10-29
CN101501499A (en) 2009-08-05
BRPI0714653A2 (en) 2013-05-07
WO2008015645A2 (en) 2008-02-07
JP2009545739A (en) 2009-12-24

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