WO2007142916A3 - Materials formable in situ within a medical device - Google Patents

Materials formable in situ within a medical device Download PDF

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Publication number
WO2007142916A3
WO2007142916A3 PCT/US2007/012639 US2007012639W WO2007142916A3 WO 2007142916 A3 WO2007142916 A3 WO 2007142916A3 US 2007012639 W US2007012639 W US 2007012639W WO 2007142916 A3 WO2007142916 A3 WO 2007142916A3
Authority
WO
WIPO (PCT)
Prior art keywords
situ
medical device
functional groups
polymer precursor
solid
Prior art date
Application number
PCT/US2007/012639
Other languages
French (fr)
Other versions
WO2007142916A2 (en
Inventor
Farhad Khosravi
James Dreher
Original Assignee
Incept Llc
Farhad Khosravi
James Dreher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incept Llc, Farhad Khosravi, James Dreher filed Critical Incept Llc
Priority to EP07795435.2A priority Critical patent/EP2029217B1/en
Priority to ES07795435T priority patent/ES2906420T3/en
Priority to CA002652966A priority patent/CA2652966A1/en
Priority to CN2007800275055A priority patent/CN101489622B/en
Priority to AU2007255053A priority patent/AU2007255053A1/en
Priority to JP2009513234A priority patent/JP2009538695A/en
Publication of WO2007142916A2 publication Critical patent/WO2007142916A2/en
Publication of WO2007142916A3 publication Critical patent/WO2007142916A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924Material characteristic
    • Y10S623/926Synthetic

Abstract

Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.
PCT/US2007/012639 2006-05-30 2007-05-29 Materials formable in situ within a medical device WO2007142916A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP07795435.2A EP2029217B1 (en) 2006-05-30 2007-05-29 Materials formable in situ within a medical device
ES07795435T ES2906420T3 (en) 2006-05-30 2007-05-29 Formable materials in situ within a medical device
CA002652966A CA2652966A1 (en) 2006-05-30 2007-05-29 Materials formable in situ within a medical device
CN2007800275055A CN101489622B (en) 2006-05-30 2007-05-29 Materials formable in situ within a medical device
AU2007255053A AU2007255053A1 (en) 2006-05-30 2007-05-29 Materials formable in situ within a medical device
JP2009513234A JP2009538695A (en) 2006-05-30 2007-05-29 Materials that can be molded in situ in medical devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/443,504 US7872068B2 (en) 2006-05-30 2006-05-30 Materials formable in situ within a medical device
US11/443,504 2006-05-30

Publications (2)

Publication Number Publication Date
WO2007142916A2 WO2007142916A2 (en) 2007-12-13
WO2007142916A3 true WO2007142916A3 (en) 2008-11-27

Family

ID=38791279

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/012639 WO2007142916A2 (en) 2006-05-30 2007-05-29 Materials formable in situ within a medical device

Country Status (8)

Country Link
US (2) US7872068B2 (en)
EP (1) EP2029217B1 (en)
JP (2) JP2009538695A (en)
CN (1) CN101489622B (en)
AU (1) AU2007255053A1 (en)
CA (1) CA2652966A1 (en)
ES (1) ES2906420T3 (en)
WO (1) WO2007142916A2 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1542616B1 (en) 2002-09-20 2015-04-22 Endologix, Inc. Stent-graft with positioning anchor
US8048145B2 (en) 2004-07-22 2011-11-01 Endologix, Inc. Graft systems having filling structures supported by scaffolds and methods for their use
EP1903985A4 (en) 2005-07-07 2010-04-28 Nellix Inc Systems and methods for endovascular aneurysm treatment
US20070150041A1 (en) * 2005-12-22 2007-06-28 Nellix, Inc. Methods and systems for aneurysm treatment using filling structures
WO2007127198A2 (en) * 2006-04-24 2007-11-08 Incept, Llc Protein crosslinkers, crosslinking methods and applications thereof
US20080220047A1 (en) * 2007-03-05 2008-09-11 Sawhney Amarpreet S Low-swelling biocompatible hydrogels
US9125807B2 (en) * 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
AU2009240419A1 (en) 2008-04-25 2009-10-29 Nellix, Inc. Stent graft delivery system
CA2726596A1 (en) 2008-06-04 2009-12-10 Nellix, Inc. Sealing apparatus and methods of use
EP2396070A4 (en) 2009-02-12 2012-09-19 Incept Llc Drug delivery through hydrogel plugs
US9526813B2 (en) * 2009-07-13 2016-12-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Intraluminal polymeric devices for the treatment of aneurysms
EP2459127B1 (en) 2009-07-27 2015-09-23 Endologix, Inc. Stent graft
EP3960215A1 (en) 2009-12-15 2022-03-02 Incept, LLC Implants and biodegradable fiducial markers
US20110276078A1 (en) 2009-12-30 2011-11-10 Nellix, Inc. Filling structure for a graft system and methods of use
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
US8801768B2 (en) 2011-01-21 2014-08-12 Endologix, Inc. Graft systems having semi-permeable filling structures and methods for their use
CN103648437B (en) 2011-04-06 2016-05-04 恩朵罗杰克斯国际控股有限公司 For the method and system of vascular aneurysms treatment
US9133045B2 (en) 2012-07-11 2015-09-15 Empire Technology Development Llc Methods and water treatment systems for reducing bisphenol A release
WO2014159093A1 (en) 2013-03-14 2014-10-02 Endologix, Inc. Method for forming materials in situ within a medical device
US10842969B2 (en) 2013-10-25 2020-11-24 Mercator Medsystems, Inc. Systems and methods of treating malacia by local delivery of hydrogel to augment tissue
US10085729B2 (en) 2014-03-06 2018-10-02 Ethicon, Inc. Methods and devices for forming biomedical coatings using variable mixing ratios of multi-part compositions
WO2015134906A1 (en) * 2014-03-07 2015-09-11 Endologix, Inc. Forming hydrogels and materials therefor
KR102440051B1 (en) 2014-03-21 2022-09-06 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
US9855317B2 (en) 2015-04-27 2018-01-02 Reflex Medical, Inc. Systems and methods for sympathetic cardiopulmonary neuromodulation
CA2993182A1 (en) 2015-07-22 2017-01-26 Incept, Llc Coated punctal plug
EP3402876B1 (en) 2016-01-13 2021-10-13 University of Pittsburgh- Of the Commonwealth System of Higher Education Vascular extracellular matrix hydrogel
WO2017139487A1 (en) 2016-02-09 2017-08-17 Northwind Medical, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
EP3478287A4 (en) 2016-06-29 2020-04-08 Tulavi Therapeutics, Inc. Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
JP2021500133A (en) * 2017-10-23 2021-01-07 エンドーロジックス インコーポレイテッド Intraluminal devices and polymers
US11730865B2 (en) 2018-05-15 2023-08-22 Incept, Llc Embolic compositions and methods
AU2019299519A1 (en) 2018-07-02 2021-01-28 Incept Llc Methods and devices for in situ formed nerve cap

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341218A (en) * 1978-05-30 1982-07-27 University Of California Detachable balloon catheter

Family Cites Families (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833003A (en) 1972-07-05 1974-09-03 A Taricco Intravascular occluding catheter
WO1980000007A1 (en) 1978-06-02 1980-01-10 A Rockey Medical sleeve
JPS6024807B2 (en) 1979-02-19 1985-06-14 昭和電工株式会社 Method for producing super absorbent hydrogel
US4311146A (en) 1980-05-08 1982-01-19 Sorenson Research Co., Inc. Detachable balloon catheter apparatus and method
FR2516796B1 (en) 1981-11-20 1986-06-06 Altulor Sa COMPOSITIONS FOR SURGICAL CEMENT BASED ON AT LEAST ONE ACRYLIC MONOMER AND AT LEAST ONE ACRYLIC POLYMER
MX163953B (en) 1984-03-27 1992-07-03 Univ New Jersey Med PROCEDURE FOR PREPARING A BIODEGRADABLE COLLAGEN MATRIX
US4728328A (en) 1984-10-19 1988-03-01 Research Corporation Cuffed tubular organic prostheses
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5306500A (en) 1988-11-21 1994-04-26 Collagen Corporation Method of augmenting tissue with collagen-polymer conjugates
IL90193A (en) 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5272012A (en) 1989-06-23 1993-12-21 C. R. Bard, Inc. Medical apparatus having protective, lubricious coating
US5487897A (en) 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
GB8927282D0 (en) 1989-12-01 1990-01-31 Univ Strathclyde Vascular surgical devices
US5334024A (en) 1990-03-21 1994-08-02 Core-Vent Corporation Transfer abutment
US6517824B1 (en) 1990-05-14 2003-02-11 University Of Medicine & Denistry Of New Jersey Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor
US5266325A (en) 1990-09-28 1993-11-30 Hydro Med Science Division Of National Patent Development Corp. Preparation of homogeneous hydrogel copolymers
US5462990A (en) 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
DE69121587T3 (en) 1990-12-06 2000-05-31 Gore & Ass IMPLANTABLE BIORESORBABLE ITEMS
JP2759305B2 (en) * 1991-03-08 1998-05-28 株式会社ニッショー Medical tubing
JP3356447B2 (en) 1991-10-16 2002-12-16 テルモ株式会社 Vascular lesion embolic material composed of dried polymer gel
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5258042A (en) 1991-12-16 1993-11-02 Henry Ford Health System Intravascular hydrogel implant
WO1993022986A1 (en) 1992-05-08 1993-11-25 Schneider (Usa) Inc. Esophageal stent and delivery tool
US5629008A (en) 1992-06-02 1997-05-13 C.R. Bard, Inc. Method and device for long-term delivery of drugs
US5514379A (en) 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
WO1994006460A1 (en) 1992-09-21 1994-03-31 Vitaphore Corporation Embolization plugs for blood vessels
US5530528A (en) 1992-09-28 1996-06-25 Fujitsu Limited Image forming apparatus having contact type, one-component developing unit
WO1995008289A2 (en) 1993-09-16 1995-03-30 Scimed Life Systems, Inc. Percutaneous repair of cardiovascular anomalies and repair compositions
AT400675B (en) 1993-10-18 1996-02-26 Immuno Ag SYRINGE SET FOR STORAGE AND APPLICATION OF A MULTI-COMPONENT MATERIAL, SYRINGE DEVICE AND ACTUATING DEVICE THEREFOR, AND METHOD FOR PRODUCING A FILLED, STERILE SYRINGE DEVICE
WO1995013033A1 (en) 1993-11-08 1995-05-18 Lazarus Harrison M Intraluminal vascular graft and method
DE4408435A1 (en) 1994-03-12 1995-09-14 Cassella Ag Hydrophilic, highly swellable hydrogels
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
ATE196486T1 (en) * 1994-08-10 2000-10-15 Peter Neuenschwander BIOCOMPATIBLE BLOCK COPOLYMER
US5534024A (en) 1994-11-04 1996-07-09 Aeroquip Corporation Intraluminal stenting graft
JP3182301B2 (en) 1994-11-07 2001-07-03 キヤノン株式会社 Microstructure and method for forming the same
US5665840A (en) 1994-11-18 1997-09-09 Novartis Corporation Polymeric networks from water-soluble prepolymers
US5690671A (en) 1994-12-13 1997-11-25 Micro Interventional Systems, Inc. Embolic elements and methods and apparatus for their delivery
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5962023A (en) 1995-03-06 1999-10-05 Ethicon, Inc. Hydrogels containing absorbable polyoxaamides
US5618850A (en) 1995-03-09 1997-04-08 Focal, Inc. Hydroxy-acid cosmetics
US6962979B1 (en) 1995-03-14 2005-11-08 Cohesion Technologies, Inc. Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents
CA2165728A1 (en) 1995-03-14 1996-09-15 Woonza M. Rhee Use of hydrophobic crosslinking agents to prepare crosslinked biomaterial compositions
US5612052A (en) 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6129761A (en) 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5785679A (en) * 1995-07-19 1998-07-28 Endotex Interventional Systems, Inc. Methods and apparatus for treating aneurysms and arterio-venous fistulas
US5667767A (en) 1995-07-27 1997-09-16 Micro Therapeutics, Inc. Compositions for use in embolizing blood vessels
DE69636626T2 (en) * 1995-07-28 2007-08-30 Genzyme Corp., Cambridge BIODEGRADABLE MULTIBLOKHYDROGENES AND THEIR USE AS CARRIERS FOR CONTROLLED RELEASE PHARMACOLOGICALLY ACTIVE MATERIALS AND TISSUE CONTACT MATERIALS
US5769882A (en) 1995-09-08 1998-06-23 Medtronic, Inc. Methods and apparatus for conformably sealing prostheses within body lumens
US5603991A (en) 1995-09-29 1997-02-18 Target Therapeutics, Inc. Method for coating catheter lumens
US5824037A (en) 1995-10-03 1998-10-20 Medtronic, Inc. Modular intraluminal prostheses construction and methods
US6193745B1 (en) 1995-10-03 2001-02-27 Medtronic, Inc. Modular intraluminal prosteheses construction and methods
US5591195A (en) 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US5665117A (en) 1995-11-27 1997-09-09 Rhodes; Valentine J. Endovascular prosthesis with improved sealing means for aneurysmal arterial disease and method of use
US5824040A (en) 1995-12-01 1998-10-20 Medtronic, Inc. Endoluminal prostheses and therapies for highly variable body lumens
US6576009B2 (en) 1995-12-01 2003-06-10 Medtronic Ave, Inc. Bifurcated intraluminal prostheses construction and methods
US5752974A (en) 1995-12-18 1998-05-19 Collagen Corporation Injectable or implantable biomaterials for filling or blocking lumens and voids of the body
ATE330644T1 (en) 1995-12-18 2006-07-15 Angiotech Biomaterials Corp CROSS-LINKED POLYMER MATERIALS AND METHODS FOR USE THEREOF
US6458889B1 (en) 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
WO1997025002A1 (en) 1996-01-05 1997-07-17 Medtronic, Inc. Expansible endoluminal prostheses
US6168622B1 (en) 1996-01-24 2001-01-02 Microvena Corporation Method and apparatus for occluding aneurysms
US5843160A (en) 1996-04-01 1998-12-01 Rhodes; Valentine J. Prostheses for aneurysmal and/or occlusive disease at a bifurcation in a vessel, duct, or lumen
US6544276B1 (en) 1996-05-20 2003-04-08 Medtronic Ave. Inc. Exchange method for emboli containment
US6190402B1 (en) 1996-06-21 2001-02-20 Musc Foundation For Research Development Insitu formable and self-forming intravascular flow modifier (IFM) and IFM assembly for deployment of same
US5980514A (en) 1996-07-26 1999-11-09 Target Therapeutics, Inc. Aneurysm closure device assembly
US5823198A (en) 1996-07-31 1998-10-20 Micro Therapeutics, Inc. Method and apparatus for intravasculer embolization
US6063061A (en) 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
WO1998012274A1 (en) 1996-09-23 1998-03-26 Chandrashekar Pathak Methods and devices for preparing protein concentrates
US7009034B2 (en) * 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US6258351B1 (en) 1996-11-06 2001-07-10 Shearwater Corporation Delivery of poly(ethylene glycol)-modified molecules from degradable hydrogels
EP1230902A1 (en) 1996-11-15 2002-08-14 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
AU6169998A (en) 1997-02-14 1998-09-08 Chandrashekar Pathak Biocompatible polymers and methods for their use
US6371975B2 (en) 1998-11-06 2002-04-16 Neomend, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers
EP0916362B1 (en) * 1997-03-31 2009-07-08 Kabushikikaisha Igaki Iryo Sekkei Stent for vessels
US6271278B1 (en) 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
IL134084A0 (en) 1997-07-18 2001-04-30 Infimed Inc Biodegradable macromers for the controlled release of biologically active substances
US5854382A (en) 1997-08-18 1998-12-29 Meadox Medicals, Inc. Bioresorbable compositions for implantable prostheses
US5972027A (en) 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
ES2211033T3 (en) 1998-01-07 2004-07-01 Debio Recherche Pharmaceutique S.A. DEGRADABLE HETEROBIFUNCTIONAL POLYETHYLENGLYCOL ACRYLATES AND GELS AND CONJUGATES DERIVED FROM SUCH ACRYLATES
US6395019B2 (en) 1998-02-09 2002-05-28 Trivascular, Inc. Endovascular graft
US6261305B1 (en) 1998-02-12 2001-07-17 Eclips Systems Inc. Endovascular prothesis with expandable leaf portion
US6251382B1 (en) 1998-04-17 2001-06-26 Enzon, Inc. Biodegradable high molecular weight polymeric linkers and their conjugates
US6066856A (en) 1998-05-18 2000-05-23 Children's Medical Center Corporation Radiation protective device
US6463317B1 (en) 1998-05-19 2002-10-08 Regents Of The University Of Minnesota Device and method for the endovascular treatment of aneurysms
US6296603B1 (en) 1998-05-26 2001-10-02 Isostent, Inc. Radioactive intraluminal endovascular prosthesis and method for the treatment of aneurysms
US6206930B1 (en) 1998-08-10 2001-03-27 Charlotte-Mecklenburg Hospital Authority Absorbable tissue expander
US6703047B2 (en) 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6179862B1 (en) 1998-08-14 2001-01-30 Incept Llc Methods and apparatus for in situ formation of hydrogels
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US6605294B2 (en) 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6152943A (en) 1998-08-14 2000-11-28 Incept Llc Methods and apparatus for intraluminal deposition of hydrogels
DE69943297D1 (en) 1998-08-14 2011-05-05 Incept Llc APPARATUS FOR IN-SITU-EDUCATION OF HYDROGELS
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
WO2000012018A1 (en) 1998-08-26 2000-03-09 Advanced Closure Systems, Inc. Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers or covering structures
US6196230B1 (en) 1998-09-10 2001-03-06 Percardia, Inc. Stent delivery system and method of use
EP1137373A4 (en) 1998-12-04 2004-05-19 Chandrashekhar P Pathak Biocompatible crosslinked polymers
GB9904722D0 (en) 1999-03-03 1999-04-21 Murch Clifford R A tubular intraluminal graft
CA2368617C (en) 1999-04-12 2010-03-16 Cornell Research Foundation, Inc. Hydrogel-forming system with hydrophobic and hydrophilic components
US6312725B1 (en) 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
US6268405B1 (en) 1999-05-04 2001-07-31 Porex Surgical, Inc. Hydrogels and methods of making and using same
US6663607B2 (en) 1999-07-12 2003-12-16 Scimed Life Systems, Inc. Bioactive aneurysm closure device assembly and kit
DK1218437T3 (en) 1999-08-27 2009-10-19 Angiodevice Internat Gmbh Preparations forming interpenetrating polymer networks for use as high-strength medical sealants
US6358557B1 (en) * 1999-09-10 2002-03-19 Sts Biopolymers, Inc. Graft polymerization of substrate surfaces
US6409757B1 (en) 1999-09-15 2002-06-25 Eva Corporation Method and apparatus for supporting a graft assembly
US6312462B1 (en) 1999-09-22 2001-11-06 Impra, Inc. Prosthesis for abdominal aortic aneurysm repair
AUPQ302899A0 (en) 1999-09-23 1999-10-21 Endogad Research Pty Limited Implants for the use in the treatment of aneurysmal disease
US6710126B1 (en) 1999-11-15 2004-03-23 Bio Cure, Inc. Degradable poly(vinyl alcohol) hydrogels
US6331184B1 (en) 1999-12-10 2001-12-18 Scimed Life Systems, Inc. Detachable covering for an implantable medical device
US6663667B2 (en) 1999-12-29 2003-12-16 Edwards Lifesciences Corporation Towel graft means for enhancing tissue ingrowth in vascular grafts
US6312463B1 (en) 2000-02-01 2001-11-06 Endotex Interventional Systems, Inc. Micro-porous mesh stent with hybrid structure
EP1259192B1 (en) 2000-03-03 2003-12-10 Cook Incorporated Endovascular device having a stent
ATE373682T1 (en) * 2000-03-13 2007-10-15 Biocure Inc EMBOLIC COMPOSITIONS
US20020026217A1 (en) 2000-04-26 2002-02-28 Steven Baker Apparatus and method for repair of perigraft flow
US6692486B2 (en) 2000-05-10 2004-02-17 Minnesota Medical Physics, Llc Apparatus and method for treatment of cerebral aneurysms, arterial-vascular malformations and arterial fistulas
US6964667B2 (en) 2000-06-23 2005-11-15 Sdgi Holdings, Inc. Formed in place fixation system with thermal acceleration
US6773454B2 (en) 2000-08-02 2004-08-10 Michael H. Wholey Tapered endovascular stent graft and method of treating abdominal aortic aneurysms and distal iliac aneurysms
EP1325044B1 (en) * 2000-09-29 2004-09-01 Basf Aktiengesellschaft Aqueous polymer dispersion
US6730119B1 (en) 2000-10-06 2004-05-04 Board Of Regents Of The University Of Texas System Percutaneous implantation of partially covered stents in aneurysmally dilated arterial segments with subsequent embolization and obliteration of the aneurysm cavity
US6610033B1 (en) 2000-10-13 2003-08-26 Incept, Llc Dual component medicinal polymer delivery system and methods of use
GB0114918D0 (en) 2001-06-19 2001-08-08 Vortex Innovation Ltd Devices for repairing aneurysms
JP2003010314A (en) * 2001-06-28 2003-01-14 Tamotsu Murakami Vascular embolus composition
US20030014075A1 (en) 2001-07-16 2003-01-16 Microvention, Inc. Methods, materials and apparatus for deterring or preventing endoleaks following endovascular graft implanation
ATE294535T1 (en) 2001-07-26 2005-05-15 Univ Oregon Health Sciences CLOSURE DEVICE FOR A VESSEL AND ATTACHMENT DEVICE
AUPR847201A0 (en) * 2001-10-26 2001-11-15 Cook Incorporated Endoluminal graft
US20030130725A1 (en) 2002-01-08 2003-07-10 Depalma Donald F. Sealing prosthesis
US20030135269A1 (en) 2002-01-16 2003-07-17 Swanstrom Lee L. Laparoscopic-assisted endovascular/endoluminal graft placement
US20040131582A1 (en) 2002-02-26 2004-07-08 Grinstaff Mark W. Novel dendritic polymers and their biomedical uses
US7131991B2 (en) 2002-04-24 2006-11-07 Medtronic Vascular, Inc. Endoluminal prosthetic assembly and extension method
US6918926B2 (en) 2002-04-25 2005-07-19 Medtronic Vascular, Inc. System for transrenal/intraostial fixation of endovascular prosthesis
US20030204249A1 (en) 2002-04-25 2003-10-30 Michel Letort Endovascular stent graft and fixation cuff
US7338511B2 (en) * 2002-05-24 2008-03-04 Boston Scientific-Scimed, Inc. Solid embolic material with variable expansion
US6833003B2 (en) 2002-06-24 2004-12-21 Cordis Neurovascular Expandable stent and delivery system
JP2004063081A (en) 2002-07-24 2004-02-26 Renesas Technology Corp Socket for semiconductor package
US7175652B2 (en) 2002-08-20 2007-02-13 Cook Incorporated Stent graft with improved proximal end
US20040098096A1 (en) 2002-10-22 2004-05-20 The University Of Miami Endograft device to inhibit endoleak and migration
US8545830B2 (en) 2003-03-24 2013-10-01 University Of Tennessee Research Foundation Multi-functional polymeric materials and their uses
JP2004313759A (en) * 2003-03-31 2004-11-11 Toray Ind Inc Blood vessel embolus material
US20050028484A1 (en) 2003-06-20 2005-02-10 Littlewood Richard W. Method and apparatus for sleeving compressed bale materials
JP2005027840A (en) * 2003-07-11 2005-02-03 National Institute For Materials Science Medical appliance for soft biotissue
US8048042B2 (en) * 2003-07-22 2011-11-01 Medtronic Vascular, Inc. Medical articles incorporating surface capillary fiber
US9687368B2 (en) * 2003-08-13 2017-06-27 Medtronic Vascular, Inc. Biocompatible controlled release coatings for medical devices and related methods
US20050065592A1 (en) 2003-09-23 2005-03-24 Asher Holzer System and method of aneurism monitoring and treatment
US20050271727A1 (en) 2004-06-07 2005-12-08 Callisyn Pharmaceuticals, Inc. Biodegradable and biocompatible crosslinked polymer hydrogel prepared from PVA and/or PEG macromer mixtures
CN102499729B (en) 2004-06-23 2015-07-22 直空间有限公司 Device system and method for tissue displacement or separation
EP1778131B1 (en) 2004-07-22 2012-01-11 Nellix, Inc. Systems for endovascular aneurysm treatment
WO2006078770A2 (en) 2005-01-21 2006-07-27 Civco Medical Instruments Co., Inc. Creating temporary space between body tissues
EP1853259A1 (en) 2005-02-09 2007-11-14 Macusight, Inc. Formulations for ocular treatment
US20060222596A1 (en) * 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US20080220047A1 (en) 2007-03-05 2008-09-11 Sawhney Amarpreet S Low-swelling biocompatible hydrogels

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341218A (en) * 1978-05-30 1982-07-27 University Of California Detachable balloon catheter

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US20110092613A1 (en) 2011-04-21
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