WO2007137119B1 - Chip-based flow cytometer type systems for analyzing fluorescently tagged particles - Google Patents
Chip-based flow cytometer type systems for analyzing fluorescently tagged particlesInfo
- Publication number
- WO2007137119B1 WO2007137119B1 PCT/US2007/069147 US2007069147W WO2007137119B1 WO 2007137119 B1 WO2007137119 B1 WO 2007137119B1 US 2007069147 W US2007069147 W US 2007069147W WO 2007137119 B1 WO2007137119 B1 WO 2007137119B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fluid
- channel
- flow
- sample
- chip
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1484—Electro-optical investigation, e.g. flow cytometers microstructural devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Abstract
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07797550A EP2021766A2 (en) | 2006-05-17 | 2007-05-17 | Chip-based flow cytometer type systems for analyzing fluorescently tagged particles |
CA002657970A CA2657970A1 (en) | 2006-05-17 | 2007-05-17 | Chip-based flow cytometer type systems for analyzing fluorescently tagged particles |
JP2009511233A JP2009537826A (en) | 2006-05-17 | 2007-05-17 | Chip-based flow cytometer-type system for analyzing fluorescently labeled particles |
CN2007800174923A CN101454653B (en) | 2006-05-17 | 2007-05-17 | Chip-based flow cytometer type systems for analyzing fluorescently tagged particles |
HK09111287.0A HK1133298A1 (en) | 2006-05-17 | 2009-12-02 | Chip-based flow cytometer type systems for analyzing fluorescently tagged particles |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74748306P | 2006-05-17 | 2006-05-17 | |
US60/747,483 | 2006-05-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2007137119A2 WO2007137119A2 (en) | 2007-11-29 |
WO2007137119A3 WO2007137119A3 (en) | 2008-05-08 |
WO2007137119B1 true WO2007137119B1 (en) | 2008-07-10 |
Family
ID=38663109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/069147 WO2007137119A2 (en) | 2006-05-17 | 2007-05-17 | Chip-based flow cytometer type systems for analyzing fluorescently tagged particles |
Country Status (8)
Country | Link |
---|---|
US (2) | US9810707B2 (en) |
EP (1) | EP2021766A2 (en) |
JP (1) | JP2009537826A (en) |
KR (1) | KR20090027643A (en) |
CN (1) | CN101454653B (en) |
CA (1) | CA2657970A1 (en) |
HK (1) | HK1133298A1 (en) |
WO (1) | WO2007137119A2 (en) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ584963A (en) | 2007-10-02 | 2012-11-30 | Theranos Inc | Modular Point-of-care devices as addressible assay units with tips of assay units having interior to immobilize reagents by capillary action |
US9144383B2 (en) * | 2007-12-13 | 2015-09-29 | The Board Of Trustees Of The University Of Arkansas | Device and method for in vivo noninvasive magnetic manipulation of circulating objects in bioflows |
US20090156932A1 (en) | 2007-12-13 | 2009-06-18 | Board Of Trustees Of The University Of Arkansas | Device and method for in vivo flow cytometry using the detection of photoacoustic waves |
US9451884B2 (en) | 2007-12-13 | 2016-09-27 | Board Of Trustees Of The University Of Arkansas | Device and method for in vivo detection of clots within circulatory vessels |
US9594071B2 (en) * | 2007-12-21 | 2017-03-14 | Colin G. Hebert | Device and method for laser analysis and separation (LAS) of particles |
US8714014B2 (en) * | 2008-01-16 | 2014-05-06 | Life Technologies Corporation | System and method for acoustic focusing hardware and implementations |
US9778188B2 (en) * | 2009-03-11 | 2017-10-03 | Industrial Technology Research Institute | Apparatus and method for detection and discrimination molecular object |
DE102009029305A1 (en) * | 2009-09-09 | 2011-03-10 | Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG | Analyzer for the automated determination of a measured variable of a liquid sample |
US9482615B2 (en) | 2010-03-15 | 2016-11-01 | Industrial Technology Research Institute | Single-molecule detection system and methods |
US8865078B2 (en) | 2010-06-11 | 2014-10-21 | Industrial Technology Research Institute | Apparatus for single-molecule detection |
EP2666008B1 (en) | 2011-01-21 | 2021-08-11 | Labrador Diagnostics LLC | Systems and methods for sample use maximization |
US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US8380541B1 (en) | 2011-09-25 | 2013-02-19 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US8435738B2 (en) * | 2011-09-25 | 2013-05-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
US8840838B2 (en) | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US8741233B2 (en) * | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
US9964539B2 (en) * | 2012-07-06 | 2018-05-08 | Hitachi High-Technologies Corporation | Analysis device and analysis method |
CA2884954A1 (en) | 2012-09-25 | 2014-04-03 | Mark S. Smeltzer | Device and method for in vivo photoacoustic diagnosis and photothermal purging of infected blood |
WO2014066553A1 (en) * | 2012-10-26 | 2014-05-01 | Becton, Dickinson And Company | Devices and methods for manipulating components in a fluid sample |
US9753026B1 (en) * | 2012-12-31 | 2017-09-05 | Techshot, Inc. | Cell processing cartridge for miniature cytometer |
US9207166B2 (en) | 2013-01-31 | 2015-12-08 | Honeywell International Inc. | Micro-molded cytometer cartridge with integrated optics |
AU2014217893A1 (en) * | 2013-02-18 | 2015-07-30 | Theranos Ip Company, Llc | Systems and methods for multi-analysis |
US10422806B1 (en) | 2013-07-25 | 2019-09-24 | Theranos Ip Company, Llc | Methods for improving assays of biological samples |
EP4278979A3 (en) | 2014-12-31 | 2024-02-21 | BioVentures, LLC | Devices and methods for fractionated photoacoustic flow cytometry |
CN105181699B (en) * | 2015-09-29 | 2019-02-22 | 浙江正力安拓生物科技有限公司 | A kind of marine/vehicle-mounted terrestrial life chip detecting system of boat-carrying |
EP3355045A1 (en) | 2017-01-26 | 2018-08-01 | Eidgenössische Anstalt für Wasserversorgung, Abwasserreinigung und Gewässerschutz, Eawag | Device and method for continuous fluid sampling |
EP3354342A1 (en) | 2017-01-26 | 2018-08-01 | Eidgenössische Anstalt für Wasserversorgung, Abwasserreinigung und Gewässerschutz, Eawag | Device and method for producing individually processed fluid samples |
KR101970689B1 (en) | 2017-08-29 | 2019-04-19 | 피엠씨씨 주식회사 | Flow cytometry using optical fiber |
KR102182575B1 (en) * | 2017-10-23 | 2020-11-26 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | Optical construction method for spectral scatter flow cytometry |
WO2019181803A1 (en) | 2018-03-20 | 2019-09-26 | 住友電気工業株式会社 | Fine particle measurement device |
KR101970690B1 (en) | 2018-09-28 | 2019-08-13 | 피엠씨씨 주식회사 | Optical receiver for measuring multiple light signals |
CN111257556A (en) * | 2018-11-30 | 2020-06-09 | 深圳市帝迈生物技术有限公司 | Immunoassay analyzer and sample analysis method |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5760900A (en) | 1989-03-18 | 1998-06-02 | Canon Kabushiki Kaisha | Method and apparatus for optically measuring specimen |
NO932088L (en) * | 1993-06-08 | 1995-01-05 | Oddbjoern Gjelsnes | Device for use in liquid flow cytometry |
US6287850B1 (en) * | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
US6403367B1 (en) | 1994-07-07 | 2002-06-11 | Nanogen, Inc. | Integrated portable biological detection system |
US5682038A (en) * | 1995-04-06 | 1997-10-28 | Becton Dickinson And Company | Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations |
US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
US5736330A (en) | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
AU7398996A (en) | 1995-10-11 | 1997-04-30 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
US6586193B2 (en) * | 1996-04-25 | 2003-07-01 | Genicon Sciences Corporation | Analyte assay using particulate labels |
EP1021554B1 (en) * | 1996-04-25 | 2007-03-21 | Genicon Sciences Corporation | Analyte assay using particulate labels |
US5780857A (en) * | 1996-10-04 | 1998-07-14 | Wallac Oy | Apparatus for imaging biochemical samples on substrates |
US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
US6159739A (en) | 1997-03-26 | 2000-12-12 | University Of Washington | Device and method for 3-dimensional alignment of particles in microfabricated flow channels |
AU1080999A (en) | 1997-10-14 | 1999-05-03 | Luminex Corporation | Precision fluorescently dyed particles and methods of making and using same |
KR100593712B1 (en) | 1998-01-22 | 2006-06-30 | 루미넥스 코포레이션 | Microparticles with Multiple Fluorescent Signals |
JP4215397B2 (en) | 1998-05-14 | 2009-01-28 | ルミネックス コーポレイション | Multiple analyte diagnostic system |
US6592821B1 (en) | 1999-05-17 | 2003-07-15 | Caliper Technologies Corp. | Focusing of microparticles in microfluidic systems |
AU770678B2 (en) | 1999-05-17 | 2004-02-26 | Caliper Life Sciences, Inc. | Focusing of microparticles in microfluidic systems |
WO2001013119A1 (en) | 1999-08-17 | 2001-02-22 | Luminex Corporation | Encapsulation of fluorescent particles |
CA2319909A1 (en) * | 1999-09-30 | 2001-03-30 | Lucent Technologies Inc. | Method and apparatus for supporting multiple mobile address schemes using object-oriented programming techniques |
WO2001027590A2 (en) * | 1999-10-12 | 2001-04-19 | Becton Dickinson And Company | Optical element for flow cytometry |
US6875619B2 (en) | 1999-11-12 | 2005-04-05 | Motorola, Inc. | Microfluidic devices comprising biochannels |
JP2003531360A (en) | 2000-03-15 | 2003-10-21 | スカンディナヴィアン マイクロ バイオデヴァイシズ アクティーゼルスカブ | Method of establishing at least one outer enclosed flow in a channel |
US6635487B1 (en) | 2000-05-17 | 2003-10-21 | Caliper Technologies Corp. | Fluorescence standard for use in microfluidic instruments |
US7016022B2 (en) | 2000-08-02 | 2006-03-21 | Honeywell International Inc. | Dual use detectors for flow cytometry |
US7978329B2 (en) * | 2000-08-02 | 2011-07-12 | Honeywell International Inc. | Portable scattering and fluorescence cytometer |
US7061595B2 (en) | 2000-08-02 | 2006-06-13 | Honeywell International Inc. | Miniaturized flow controller with closed loop regulation |
US6778263B2 (en) | 2000-08-25 | 2004-08-17 | Amnis Corporation | Methods of calibrating an imaging system using calibration beads |
DE10051396A1 (en) * | 2000-10-17 | 2002-04-18 | Febit Ferrarius Biotech Gmbh | An integrated synthesis and identification of an analyte, comprises particles immobilized at a carrier to be coupled to receptors in a structured pattern to give receptor arrays for biochemical reactions |
US6608360B2 (en) | 2000-12-15 | 2003-08-19 | University Of Houston | One-chip micro-integrated optoelectronic sensor |
US6844563B2 (en) | 2001-05-22 | 2005-01-18 | Matsushita Electric Industrial Co., Ltd. | Fluorescence detecting device with integrated circuit and photodiode, and detection method |
US7105355B2 (en) * | 2001-07-18 | 2006-09-12 | The Regents Of The University Of Michigan | Flow cytometers and detection system of lesser size |
US20030186465A1 (en) * | 2001-11-27 | 2003-10-02 | Kraus Robert H. | Apparatus used in identification, sorting and collection methods using magnetic microspheres and magnetic microsphere kits |
CN1636138A (en) * | 2001-11-27 | 2005-07-06 | 长冈实业株式会社 | Magneto-optical bio-discs and systems including related methods |
GB2383127B (en) * | 2001-12-12 | 2004-10-20 | Proimmune Ltd | Device and method for investigating analytes in liquid suspension or solution |
TWI230257B (en) | 2002-10-01 | 2005-04-01 | Univ Nat Cheng Kung | Integrated analytical biochip and manufacturing method thereof |
TW577855B (en) | 2003-05-21 | 2004-03-01 | Univ Nat Cheng Kung | Chip-type micro-fluid particle 3-D focusing and detection device |
US7149396B2 (en) | 2003-06-16 | 2006-12-12 | The Regents Of The University Of California | Apparatus for optical measurements on low-index non-solid materials based on arrow waveguides |
US7282180B2 (en) * | 2003-07-02 | 2007-10-16 | Immunivest Corporation | Devices and methods to image objects |
KR101166180B1 (en) | 2003-08-13 | 2012-07-18 | 루미넥스 코포레이션 | Methods for controlling one or more parameters of a flow cytometer type measurement system |
US7221455B2 (en) | 2004-01-20 | 2007-05-22 | The Regents Of The Unversity Of California | Integrated, fluorescence-detecting microanalytical system |
CA2557549A1 (en) * | 2004-02-27 | 2005-09-09 | Board Of Regents, The University Of Texas System | System and method for integrating fluids and reagents in self-contained cartridges containing particle and membrane sensor elements |
TWI251079B (en) | 2004-06-15 | 2006-03-11 | Univ Nat Cheng Kung | Inspection chip and the manufacturing method thereof |
JP2006010529A (en) | 2004-06-25 | 2006-01-12 | Canon Inc | Separator and method for separating magnetic particle |
-
2007
- 2007-05-17 US US11/750,000 patent/US9810707B2/en active Active
- 2007-05-17 EP EP07797550A patent/EP2021766A2/en not_active Ceased
- 2007-05-17 WO PCT/US2007/069147 patent/WO2007137119A2/en active Application Filing
- 2007-05-17 CN CN2007800174923A patent/CN101454653B/en active Active
- 2007-05-17 CA CA002657970A patent/CA2657970A1/en not_active Abandoned
- 2007-05-17 JP JP2009511233A patent/JP2009537826A/en not_active Withdrawn
- 2007-05-17 KR KR1020087030779A patent/KR20090027643A/en not_active Application Discontinuation
-
2009
- 2009-12-02 HK HK09111287.0A patent/HK1133298A1/en unknown
-
2017
- 2017-09-29 US US15/720,628 patent/US20180100872A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2021766A2 (en) | 2009-02-11 |
US20070269345A1 (en) | 2007-11-22 |
JP2009537826A (en) | 2009-10-29 |
WO2007137119A2 (en) | 2007-11-29 |
KR20090027643A (en) | 2009-03-17 |
US9810707B2 (en) | 2017-11-07 |
CN101454653B (en) | 2013-01-16 |
HK1133298A1 (en) | 2010-03-19 |
CA2657970A1 (en) | 2007-11-29 |
WO2007137119A3 (en) | 2008-05-08 |
CN101454653A (en) | 2009-06-10 |
US20180100872A1 (en) | 2018-04-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2007137119B1 (en) | Chip-based flow cytometer type systems for analyzing fluorescently tagged particles | |
US20200150023A1 (en) | Instrument and Method for Optical Particle Sensing | |
JP6493897B2 (en) | Systems and methods for detecting biological conditions | |
US10234392B2 (en) | Optical engine for flow cytometer, flow cytometer system and methods of use | |
US10345303B2 (en) | Image analysis and measurement of biological samples | |
CA2992239C (en) | Cell analysis apparatus and methods | |
US20150355073A1 (en) | System and method for deforming and analyzing particles | |
EP1574838A1 (en) | Device for collecting information on biological particle | |
US10215995B2 (en) | Large area, low f-number optical system | |
US20090059207A1 (en) | Method and device for measuring photoluminescence, absorption and diffraction of microscopic objects in a fluid | |
JP2016513255A (en) | Image analysis and measurement of biological samples | |
KR20000053341A (en) | Analytical apparatus | |
US8922778B2 (en) | Apparatus and method for increasing collection efficiency in capillary based flowcytometry | |
WO1998059233A1 (en) | Interlaced lasers for multiple fluorescence measurement | |
US10324020B2 (en) | Fluidic optical cartridge | |
JP2009520198A (en) | Method and application for distinguishing at least two cell populations | |
US20030133119A1 (en) | Rapid imaging of particles in a large fluid volume through flow cell imaging | |
CN106066320B (en) | Seawater bacteria detection system based on multi-wavelength laser induced bacteria intrinsic fluorescence | |
CN109357992B (en) | Optical system for shaping light beam and flow cytometer | |
Pandey et al. | Compact 3D printed module for fluorescence and label-free imaging using evanescent excitation | |
CN115053118A (en) | Apparatus and method for circulating flow cytometry using specialized cell identification | |
Macheta et al. | The technique of flow cytometry in diagnostic research | |
Gheewala et al. | Available online through www. jpronline. info |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 200780017492.3 Country of ref document: CN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2233/MUMNP/2008 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2009511233 Country of ref document: JP |
|
ENP | Entry into the national phase |
Ref document number: 2657970 Country of ref document: CA |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2007797550 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020087030779 Country of ref document: KR |