WO2007136523A3 - Nanoelectronic breath analyzer and asthma monitor - Google Patents

Nanoelectronic breath analyzer and asthma monitor Download PDF

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Publication number
WO2007136523A3
WO2007136523A3 PCT/US2007/010836 US2007010836W WO2007136523A3 WO 2007136523 A3 WO2007136523 A3 WO 2007136523A3 US 2007010836 W US2007010836 W US 2007010836W WO 2007136523 A3 WO2007136523 A3 WO 2007136523A3
Authority
WO
WIPO (PCT)
Prior art keywords
monitor
asthma
nanoelectronic
breath analyzer
monitor system
Prior art date
Application number
PCT/US2007/010836
Other languages
French (fr)
Other versions
WO2007136523A2 (en
Inventor
Jean-Christophe P Gabriel
Vikram Joshi
Joseph Niemann
Alexander Star
David Thomas
Christian Valcke
Original Assignee
Nanomix Inc
Jean-Christophe P Gabriel
Vikram Joshi
Joseph Niemann
Alexander Star
David Thomas
Christian Valcke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/437,275 external-priority patent/US20070048180A1/en
Priority claimed from US11/488,456 external-priority patent/US20070048181A1/en
Priority claimed from US11/588,845 external-priority patent/US20080021339A1/en
Application filed by Nanomix Inc, Jean-Christophe P Gabriel, Vikram Joshi, Joseph Niemann, Alexander Star, David Thomas, Christian Valcke filed Critical Nanomix Inc
Priority to JP2009510967A priority Critical patent/JP2009537219A/en
Priority to EP07756204A priority patent/EP2029013A4/en
Publication of WO2007136523A2 publication Critical patent/WO2007136523A2/en
Publication of WO2007136523A3 publication Critical patent/WO2007136523A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4146—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS involving nanosized elements, e.g. nanotubes, nanowires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
    • G01N27/4141—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for gases

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Analytical Chemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Electrochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such as CO2, NO, anesthesia gases, and the like in human breath. An integrated multivalent monitor system is described which permits two or more analytes to be measured in breath, for example to monitor pulmonary conditions such as asthma. The monitor system may be configured to be compact, light weight, inexpensive, and to include a microprocessor capable of both analyzing measurements to determine patient status, and storing measurement history. Wireless embodiments provide such enhancements as remote monitoring.
PCT/US2007/010836 2006-05-18 2007-05-04 Nanoelectronic breath analyzer and asthma monitor WO2007136523A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2009510967A JP2009537219A (en) 2006-05-18 2007-05-04 Nanoelectronic respiratory analyzer and asthma monitor
EP07756204A EP2029013A4 (en) 2006-05-18 2007-05-04 Nanoelectronic breath analyzer and asthma monitor

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US11/437,275 US20070048180A1 (en) 2002-09-05 2006-05-18 Nanoelectronic breath analyzer and asthma monitor
US11/437,275 2006-05-18
US11/488,456 2006-07-18
US11/488,456 US20070048181A1 (en) 2002-09-05 2006-07-18 Carbon dioxide nanosensor, and respiratory CO2 monitors
US11/588,845 2006-10-26
US11/588,845 US20080021339A1 (en) 2005-10-27 2006-10-26 Anesthesia monitor, capacitance nanosensors and dynamic sensor sampling method

Publications (2)

Publication Number Publication Date
WO2007136523A2 WO2007136523A2 (en) 2007-11-29
WO2007136523A3 true WO2007136523A3 (en) 2008-10-02

Family

ID=38723762

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/010836 WO2007136523A2 (en) 2006-05-18 2007-05-04 Nanoelectronic breath analyzer and asthma monitor

Country Status (3)

Country Link
EP (1) EP2029013A4 (en)
JP (1) JP2009537219A (en)
WO (1) WO2007136523A2 (en)

Families Citing this family (28)

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Publication number Priority date Publication date Assignee Title
US7714398B2 (en) 2002-09-05 2010-05-11 Nanomix, Inc. Nanoelectronic measurement system for physiologic gases and improved nanosensor for carbon dioxide
US7522040B2 (en) 2004-04-20 2009-04-21 Nanomix, Inc. Remotely communicating, battery-powered nanostructure sensor devices
US7948041B2 (en) 2005-05-19 2011-05-24 Nanomix, Inc. Sensor having a thin-film inhibition layer
US20080107569A1 (en) * 2006-09-14 2008-05-08 Stefano George B Detecting nitric oxide
GB0717433D0 (en) * 2007-09-07 2007-10-17 Bedfont Scient Ltd Apparatus and method
JP5139186B2 (en) * 2008-07-18 2013-02-06 シャープ株式会社 Breath measurement device
JP5081754B2 (en) * 2008-07-18 2012-11-28 シャープ株式会社 HEALTH / RELAXATION DEVICE, HEALTH / RELAXATION SYSTEM, TERMINAL AND ELECTRIC DEVICE USED FOR THE SYSTEM
JP5284705B2 (en) * 2008-07-18 2013-09-11 シャープ株式会社 Disease diagnosis system, terminal device, and server device
JP5652847B2 (en) * 2009-11-10 2015-01-14 公益財団法人北九州産業学術推進機構 Method of breath analysis
US8940235B2 (en) * 2011-10-04 2015-01-27 Samsung Electronics Co., Ltd. Thin-film transistors for chemical sensor applications
FR2993999B1 (en) * 2012-07-27 2014-09-12 Nanomade Concept METHOD FOR MANUFACTURING A TRANSPARENT TOUCH SURFACE AND TOUCH SURFACE OBTAINED BY SUCH A METHOD
US8797167B2 (en) 2012-08-24 2014-08-05 Elwha Llc Computational systems and methods for monitoring medication events
US9035777B2 (en) 2012-08-24 2015-05-19 Elwha Llc Computational systems and methods for monitoring medication events including use of a camera and data comparison
US9081885B2 (en) 2012-08-24 2015-07-14 Elwha Llc Computational systems and methods for monitoring medication events including a camera and identified time intervals
US9683957B2 (en) * 2013-05-29 2017-06-20 Csir Field effect transistor and a gas detector including a plurality of field effect transistors
US9011779B1 (en) 2014-05-21 2015-04-21 Andas Inc. Device for measurement of exhaled ethanol concentration
US9366664B2 (en) 2014-05-21 2016-06-14 Andas Inc. Device for measurement of exhaled nitric oxide concentration
US11175268B2 (en) 2014-06-09 2021-11-16 Biometry Inc. Mini point of care gas chromatographic test strip and method to measure analytes
AU2015274801B2 (en) * 2014-06-09 2020-10-15 Biometry Inc. Low cost test strip and method to measure analyte
JP6586867B2 (en) 2015-12-08 2019-10-09 セイコーエプソン株式会社 Electric field enhancing element and Raman spectrometer
JP7086927B2 (en) 2016-07-19 2022-06-20 バイオメトリー・インコーポレイテッド Specimen measurement method and sample measurement system using batch calibrator test strips
JP6772948B2 (en) * 2017-04-28 2020-10-21 富士通株式会社 Gas sensor devices, gas sensor systems, and methods for manufacturing gas sensor devices
DE102017212875A1 (en) * 2017-07-26 2019-01-31 Robert Bosch Gmbh Micromechanical device and method for producing a micromechanical device
CN108742630B (en) * 2018-07-05 2023-07-25 河北工业大学 Expiration nano-sensing health early warning system and implementation method
US20200124625A1 (en) * 2018-10-19 2020-04-23 SannTek Labs Inc. Systems and methods for detecting a target analyte in a breath sample
KR102139802B1 (en) * 2019-02-01 2020-07-30 광운대학교 산학협력단 High Performance Gas Sensor Capable of Sensing Nitric Oxide at Parts-Per-Billion Level and Fabrication Method by Solution Process
US11723553B2 (en) 2019-02-11 2023-08-15 Giner, Inc. Method and system for detection and/or quantification of delta-9-tetrahydrocannabinol in exhaled breath
GB2599932A (en) * 2020-10-15 2022-04-20 Univ Leiden Gas sensing apparatus

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US6010459A (en) * 1996-04-09 2000-01-04 Silkoff; Philip E. Method and apparatus for the measurement of components of exhaled breath in humans
US20040043527A1 (en) * 2002-09-04 2004-03-04 Nanomix, Inc. Sensitivity control for nanotube sensors
US20040136866A1 (en) * 2002-06-27 2004-07-15 Nanosys, Inc. Planar nanowire based sensor elements, devices, systems and methods for using and making same
US20060021881A1 (en) * 2003-09-30 2006-02-02 Nano-Proprietary, Inc. Nanobiosensor and carbon nanotube thin film transistors

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US6974706B1 (en) * 2003-01-16 2005-12-13 University Of Florida Research Foundation, Inc. Application of biosensors for diagnosis and treatment of disease
US7052854B2 (en) * 2001-05-23 2006-05-30 University Of Florida Research Foundation, Inc. Application of nanotechnology and sensor technologies for ex-vivo diagnostics
US7192782B2 (en) * 2002-01-11 2007-03-20 Ekips Technologies, Inc. Method and apparatus for determining marker gas concentration in exhaled breath using an internal calibrating gas
US7522040B2 (en) * 2004-04-20 2009-04-21 Nanomix, Inc. Remotely communicating, battery-powered nanostructure sensor devices
US20050129573A1 (en) * 2003-09-12 2005-06-16 Nanomix, Inc. Carbon dioxide nanoelectronic sensor
WO2005062031A1 (en) * 2003-09-05 2005-07-07 Nanomix, Inc. Nanoelectronic capnometer adapter

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US6010459A (en) * 1996-04-09 2000-01-04 Silkoff; Philip E. Method and apparatus for the measurement of components of exhaled breath in humans
US20040136866A1 (en) * 2002-06-27 2004-07-15 Nanosys, Inc. Planar nanowire based sensor elements, devices, systems and methods for using and making same
US20040043527A1 (en) * 2002-09-04 2004-03-04 Nanomix, Inc. Sensitivity control for nanotube sensors
US20060021881A1 (en) * 2003-09-30 2006-02-02 Nano-Proprietary, Inc. Nanobiosensor and carbon nanotube thin film transistors

Non-Patent Citations (1)

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Title
See also references of EP2029013A4 *

Also Published As

Publication number Publication date
EP2029013A4 (en) 2011-09-28
JP2009537219A (en) 2009-10-29
EP2029013A2 (en) 2009-03-04
WO2007136523A2 (en) 2007-11-29

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