WO2007134167A3 - Computational analysis of the synergy among multiple interacting factors - Google Patents

Computational analysis of the synergy among multiple interacting factors Download PDF

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Publication number
WO2007134167A3
WO2007134167A3 PCT/US2007/068666 US2007068666W WO2007134167A3 WO 2007134167 A3 WO2007134167 A3 WO 2007134167A3 US 2007068666 W US2007068666 W US 2007068666W WO 2007134167 A3 WO2007134167 A3 WO 2007134167A3
Authority
WO
WIPO (PCT)
Prior art keywords
factors
synergy
computational analysis
multiple interacting
interacting factors
Prior art date
Application number
PCT/US2007/068666
Other languages
French (fr)
Other versions
WO2007134167A9 (en
WO2007134167A2 (en
Inventor
Dimitris Anastassiou
Vinay Varadan
Original Assignee
Univ Columbia
Dimitris Anastassiou
Vinay Varadan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia, Dimitris Anastassiou, Vinay Varadan filed Critical Univ Columbia
Priority to US12/307,694 priority Critical patent/US8234077B2/en
Publication of WO2007134167A2 publication Critical patent/WO2007134167A2/en
Publication of WO2007134167A3 publication Critical patent/WO2007134167A3/en
Publication of WO2007134167A9 publication Critical patent/WO2007134167A9/en
Priority to US13/534,578 priority patent/US20120290218A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring Volume Flow (AREA)
  • Complex Calculations (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Systems and methods for selecting factors from a data set of measurements are provided. The measurements include values of factors and/or outcomes. Two or more factors that are jointly associated with one or more outcomes from the data set are identified. Each of the two or more factors are analyzed to determine at least one cooperative interaction among the factors with respect to an outcome. The two or more factors can be a module of factors.
PCT/US2007/068666 2006-05-10 2007-05-10 Computational analysis of the synergy among multiple interacting factors WO2007134167A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/307,694 US8234077B2 (en) 2006-05-10 2007-05-10 Method of selecting genes from gene expression data based on synergistic interactions among the genes
US13/534,578 US20120290218A1 (en) 2006-05-10 2012-06-27 Computational Analysis of the Synergy Among Multiple Interacting Factors

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79927106P 2006-05-10 2006-05-10
US60/799,271 2006-05-10
US88534907P 2007-01-17 2007-01-17
US60/885,349 2007-01-17

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/534,578 Division US20120290218A1 (en) 2006-05-10 2012-06-27 Computational Analysis of the Synergy Among Multiple Interacting Factors

Publications (3)

Publication Number Publication Date
WO2007134167A2 WO2007134167A2 (en) 2007-11-22
WO2007134167A3 true WO2007134167A3 (en) 2008-10-16
WO2007134167A9 WO2007134167A9 (en) 2008-11-27

Family

ID=38694700

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/068666 WO2007134167A2 (en) 2006-05-10 2007-05-10 Computational analysis of the synergy among multiple interacting factors

Country Status (2)

Country Link
US (2) US8234077B2 (en)
WO (1) WO2007134167A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007067956A2 (en) * 2005-12-07 2007-06-14 The Trustees Of Columbia University In The City Of New York System and method for multiple-factor selection
WO2007134167A2 (en) 2006-05-10 2007-11-22 The Trustees Of Columbia University In The City Of New York Computational analysis of the synergy among multiple interacting factors
US8086409B2 (en) 2007-01-30 2011-12-27 The Trustees Of Columbia University In The City Of New York Method of selecting genes from continuous gene expression data based on synergistic interactions among genes
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030215866A1 (en) * 2002-05-01 2003-11-20 Liebovitch Larry S. Models of genetic interactions and methods of use
US6996476B2 (en) * 2003-11-07 2006-02-07 University Of North Carolina At Charlotte Methods and systems for gene expression array analysis

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL277716A (en) * 1962-04-27
US3354297A (en) * 1964-02-06 1967-11-21 Ford Motor Co Apparatus for measuring dynamic characteristics of systems by crosscorrelation
US3535084A (en) * 1965-05-29 1970-10-20 Katsuhisa Furuta Automatic and continuous analysis of multiple components
US3449553A (en) * 1965-08-23 1969-06-10 United Geophysical Corp Computer for determining the correlation function of variable signals
US5697369A (en) * 1988-12-22 1997-12-16 Biofield Corp. Method and apparatus for disease, injury and bodily condition screening or sensing
US5597719A (en) * 1994-07-14 1997-01-28 Onyx Pharmaceuticals, Inc. Interaction of RAF-1 and 14-3-3 proteins
US6110109A (en) * 1999-03-26 2000-08-29 Biosignia, Inc. System and method for predicting disease onset
US20040253637A1 (en) * 2001-04-13 2004-12-16 Biosite Incorporated Markers for differential diagnosis and methods of use thereof
DE10159262B4 (en) * 2001-12-03 2007-12-13 Siemens Ag Identify pharmaceutical targets
EP1550074A4 (en) 2002-08-22 2009-10-21 Agency Science Tech & Res Prediction by collective likelihood from emerging patterns
EP1613734A4 (en) * 2003-04-04 2007-04-18 Agilent Technologies Inc Visualizing expression data on chromosomal graphic schemes
WO2005101981A2 (en) * 2004-04-27 2005-11-03 Yeda Research And Development Co. Ltd. Autonomous molecular computer diagnoses molecular disease markers and administers requisite drug in vitro
US20070178526A1 (en) * 2005-07-20 2007-08-02 Kountakis Stilianos E Use of protein profiles in disease diagnosis and treatment
WO2007067956A2 (en) 2005-12-07 2007-06-14 The Trustees Of Columbia University In The City Of New York System and method for multiple-factor selection
WO2007134167A2 (en) 2006-05-10 2007-11-22 The Trustees Of Columbia University In The City Of New York Computational analysis of the synergy among multiple interacting factors
US8086409B2 (en) * 2007-01-30 2011-12-27 The Trustees Of Columbia University In The City Of New York Method of selecting genes from continuous gene expression data based on synergistic interactions among genes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030215866A1 (en) * 2002-05-01 2003-11-20 Liebovitch Larry S. Models of genetic interactions and methods of use
US6996476B2 (en) * 2003-11-07 2006-02-07 University Of North Carolina At Charlotte Methods and systems for gene expression array analysis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BASSETT ET AL.: "Gene Expression Informatics - It's All in Your mine", NATURE GENETICS, vol. 21, no. 1S, January 1999 (1999-01-01), pages 51 - 55, XP000996663 *
BRAZMA ET AL.: "Gene Expression Data Analysis", FEBS LETT., vol. 480, no. 1, August 2000 (2000-08-01), pages 17 - 24, XP004337488 *

Also Published As

Publication number Publication date
US20090299643A1 (en) 2009-12-03
US8234077B2 (en) 2012-07-31
WO2007134167A9 (en) 2008-11-27
US20120290218A1 (en) 2012-11-15
WO2007134167A2 (en) 2007-11-22

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