WO2007081453A3 - Method and apparatus for determining liquid volume - Google Patents
Method and apparatus for determining liquid volume Download PDFInfo
- Publication number
- WO2007081453A3 WO2007081453A3 PCT/US2006/046272 US2006046272W WO2007081453A3 WO 2007081453 A3 WO2007081453 A3 WO 2007081453A3 US 2006046272 W US2006046272 W US 2006046272W WO 2007081453 A3 WO2007081453 A3 WO 2007081453A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solution
- aliquot
- wavelengths
- volume
- absorbance
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F22/00—Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
Abstract
A method, apparatus and kit for precisely and accurately determining the volume of a liquid aliquot which can be used to calibrate a liquid delivery device. Two dye-containing solutions, a sample solution and a diluent solution, are prepared such that each solution contains a different dye, with the solutions having different absorbance values at a first wavelength and at a second wavelength. The absorbance value of a known volume of diluent solution is measured at both wavelengths. Either one aliquot of sample solution is added to the diluent solution and then absorbance measurements are made at both wavelengths, or multiple aliquots of sample solution are mixed serially into the diluent solution and then absorbance measurements are made at both wavelengths after each aliquot is added. The volume of any single aliquot is calculated by using a two-step formula which is based on the Beer-Lambert law.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/326,858 | 2006-01-06 | ||
US11/326,858 US7772008B2 (en) | 2006-01-06 | 2006-01-06 | Method and apparatus for determining liquid volume |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007081453A2 WO2007081453A2 (en) | 2007-07-19 |
WO2007081453A3 true WO2007081453A3 (en) | 2007-12-13 |
Family
ID=38233199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/046272 WO2007081453A2 (en) | 2006-01-06 | 2006-12-05 | Method and apparatus for determining liquid volume |
Country Status (2)
Country | Link |
---|---|
US (1) | US7772008B2 (en) |
WO (1) | WO2007081453A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7998747B2 (en) * | 2006-09-15 | 2011-08-16 | Artel, Inc. | Quantitative dual-dye photometric method for determining dilution impact |
WO2009042170A1 (en) | 2007-09-26 | 2009-04-02 | Medtronic, Inc. | Therapy program selection |
US7791716B2 (en) * | 2008-04-07 | 2010-09-07 | Artel, Inc. | System and method for liquid delivery evaluation using solutions with multiple light absorbance spectral features |
US8404158B2 (en) * | 2008-04-07 | 2013-03-26 | Artel, Inc. | System and method for liquid delivery evaluation using solutions with multiple light absorbance spectral features |
US9588132B2 (en) | 2011-04-08 | 2017-03-07 | Artel, Inc. | Validation method for automated analyzers |
US9255830B2 (en) | 2012-05-21 | 2016-02-09 | Common Sensing Inc. | Dose measurement system and method |
US8817258B2 (en) | 2012-05-21 | 2014-08-26 | Common Sensing Inc. | Dose measurement system and method |
US20150140679A1 (en) | 2012-06-27 | 2015-05-21 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for liquid mixing assessment |
EP2872873B1 (en) | 2012-07-13 | 2018-02-28 | Artel, Inc. | Vertical and horizontal beam hybrid pipette calibration system |
CA2952844A1 (en) * | 2014-08-01 | 2016-02-04 | Common Sensing Inc. | Liquid measurement systems, apparatus, and methods optimized with temperature sensing |
DK3485237T3 (en) | 2016-07-15 | 2024-02-26 | Bigfoot Biomedical Inc | Dose measurement systems |
EP3299470B1 (en) * | 2016-09-23 | 2019-10-30 | Roche Diagniostics GmbH | A method for reducing quantification errors caused by reaction volume deviations in digital polymerase chain reaction |
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US5492673A (en) * | 1992-02-28 | 1996-02-20 | Artel, Inc. | Reagent system for calibration of pipettes and other volumetric measuring devices |
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US6741365B2 (en) * | 2001-12-12 | 2004-05-25 | Artel, Inc. | Photometric calibration of liquid volumes |
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US6496260B1 (en) * | 1998-12-23 | 2002-12-17 | Molecular Devices Corp. | Vertical-beam photometer for determination of light absorption pathlength |
WO2002040161A1 (en) * | 2000-11-17 | 2002-05-23 | Tecan Trading Ag | Method and device for determining the volume of a sample of a liquid |
US6929951B2 (en) * | 2002-02-28 | 2005-08-16 | Agilent Technologies, Inc. | Method and system for molecular array scanner calibration |
US7061608B2 (en) * | 2004-01-30 | 2006-06-13 | Artel, Inc. | Apparatus and method for calibration of spectrophotometers |
-
2006
- 2006-01-06 US US11/326,858 patent/US7772008B2/en active Active
- 2006-12-05 WO PCT/US2006/046272 patent/WO2007081453A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5492673A (en) * | 1992-02-28 | 1996-02-20 | Artel, Inc. | Reagent system for calibration of pipettes and other volumetric measuring devices |
US6741365B2 (en) * | 2001-12-12 | 2004-05-25 | Artel, Inc. | Photometric calibration of liquid volumes |
US6661512B2 (en) * | 2002-02-13 | 2003-12-09 | Varian, Inc. | Sample analysis system with fiber optics and related method |
Also Published As
Publication number | Publication date |
---|---|
US20070161114A1 (en) | 2007-07-12 |
WO2007081453A2 (en) | 2007-07-19 |
US7772008B2 (en) | 2010-08-10 |
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