WO2007079191A3 - System for characterizing a patient's propensity for a neurological event - Google Patents

System for characterizing a patient's propensity for a neurological event Download PDF

Info

Publication number
WO2007079191A3
WO2007079191A3 PCT/US2006/049501 US2006049501W WO2007079191A3 WO 2007079191 A3 WO2007079191 A3 WO 2007079191A3 US 2006049501 W US2006049501 W US 2006049501W WO 2007079191 A3 WO2007079191 A3 WO 2007079191A3
Authority
WO
WIPO (PCT)
Prior art keywords
patient
propensity
characterizing
neurological event
pharmacological agent
Prior art date
Application number
PCT/US2006/049501
Other languages
French (fr)
Other versions
WO2007079191A2 (en
Inventor
Mike Bland
Kent W Leyde
David Snyder
Daniel J Dilorenzo
Original Assignee
Neurovista Corp
Mike Bland
Kent W Leyde
David Snyder
Daniel J Dilorenzo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurovista Corp, Mike Bland, Kent W Leyde, David Snyder, Daniel J Dilorenzo filed Critical Neurovista Corp
Priority to EP06848288A priority Critical patent/EP1977389A4/en
Publication of WO2007079191A2 publication Critical patent/WO2007079191A2/en
Publication of WO2007079191A3 publication Critical patent/WO2007079191A3/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation

Abstract

The present invention provides systems and methods for managing intake of a pharmacological agent. In one method of the present invention, the systems and methods are for controlling intake of an anti-epileptic drug. In such embodiments, one or more signals from a patient are processed to predict an onset of a seizure. Upon the prediction of the seizure, the patient is allowed to access the pharmacological agent in a pharmacological agent dispenser.
PCT/US2006/049501 2005-12-28 2006-12-28 System for characterizing a patient's propensity for a neurological event WO2007079191A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06848288A EP1977389A4 (en) 2005-12-28 2006-12-28 System for characterizing a patient's propensity for a neurological event

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/322,150 US20070149952A1 (en) 2005-12-28 2005-12-28 Systems and methods for characterizing a patient's propensity for a neurological event and for communicating with a pharmacological agent dispenser
US11/322,150 2005-12-28

Publications (2)

Publication Number Publication Date
WO2007079191A2 WO2007079191A2 (en) 2007-07-12
WO2007079191A3 true WO2007079191A3 (en) 2007-11-29

Family

ID=38194884

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/049501 WO2007079191A2 (en) 2005-12-28 2006-12-28 System for characterizing a patient's propensity for a neurological event

Country Status (3)

Country Link
US (1) US20070149952A1 (en)
EP (1) EP1977389A4 (en)
WO (1) WO2007079191A2 (en)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9415222B2 (en) 1998-08-05 2016-08-16 Cyberonics, Inc. Monitoring an epilepsy disease state with a supervisory module
US7209787B2 (en) 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US9113801B2 (en) 1998-08-05 2015-08-25 Cyberonics, Inc. Methods and systems for continuous EEG monitoring
US7780981B2 (en) 2004-09-13 2010-08-24 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US8818496B2 (en) 2005-10-14 2014-08-26 Medicalgorithmics Ltd. Systems for safe and remote outpatient ECG monitoring
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
ES2538726T3 (en) 2006-03-29 2015-06-23 Dignity Health Vagus nerve stimulation system
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
WO2007139861A2 (en) * 2006-05-22 2007-12-06 The Trustees Of The University Of Pennsylvania Method and device for the recording, localization and stimulation-based mapping of epileptic seizures and brain function utilizing the intracranial and extracranial cerebral vasulature and/or central and/or peripheral nervous system
US20080027515A1 (en) * 2006-06-23 2008-01-31 Neuro Vista Corporation A Delaware Corporation Minimally Invasive Monitoring Systems
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US8295934B2 (en) 2006-11-14 2012-10-23 Neurovista Corporation Systems and methods of reducing artifact in neurological stimulation systems
US20080183097A1 (en) * 2007-01-25 2008-07-31 Leyde Kent W Methods and Systems for Measuring a Subject's Susceptibility to a Seizure
EP2126785A2 (en) 2007-01-25 2009-12-02 NeuroVista Corporation Systems and methods for identifying a contra-ictal condition in a subject
US8036736B2 (en) 2007-03-21 2011-10-11 Neuro Vista Corporation Implantable systems and methods for identifying a contra-ictal condition in a subject
US20080255582A1 (en) * 2007-04-11 2008-10-16 Harris John F Methods and Template Assembly for Implanting an Electrode Array in a Patient
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US9788744B2 (en) 2007-07-27 2017-10-17 Cyberonics, Inc. Systems for monitoring brain activity and patient advisory device
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US20090171168A1 (en) 2007-12-28 2009-07-02 Leyde Kent W Systems and Method for Recording Clinical Manifestations of a Seizure
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US9443141B2 (en) * 2008-06-02 2016-09-13 New York University Method, system, and computer-accessible medium for classification of at least one ICTAL state
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
WO2010055409A2 (en) 2008-11-17 2010-05-20 Medicalgorithmics Ltd. Outpatient monitoring systems and methods
US9585562B2 (en) * 2008-12-03 2017-03-07 Carefusion 303, Inc. Method and apparatus for automatically integrating a medical device into a medical facility network
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
US8588933B2 (en) 2009-01-09 2013-11-19 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
US8786624B2 (en) 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
JP5395954B2 (en) * 2009-06-26 2014-01-22 ヴェーデクス・アクティーセルスカプ EEG monitoring system and method for monitoring EEG
SG182687A1 (en) * 2010-02-01 2012-08-30 Widex As Portable eeg monitor system with wireless communication
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
US8562523B2 (en) 2011-03-04 2013-10-22 Flint Hills Scientific, Llc Detecting, assessing and managing extreme epileptic events
US8562524B2 (en) 2011-03-04 2013-10-22 Flint Hills Scientific, Llc Detecting, assessing and managing a risk of death in epilepsy
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US8812098B2 (en) * 2011-04-28 2014-08-19 Medtronic, Inc. Seizure probability metrics
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US9489636B2 (en) 2012-04-18 2016-11-08 Tagasauris, Inc. Task-agnostic integration of human and machine intelligence
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
GB201209975D0 (en) * 2012-06-06 2012-07-18 Univ Exeter Assessing susceptibility to epilepsy and epileptic seizures
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
US10098582B1 (en) * 2013-05-16 2018-10-16 Cerner Innovations, Inc. Characterizing sleep architecture
US20150235000A1 (en) * 2014-02-19 2015-08-20 International Business Machines Corporation Developing health information feature abstractions from intra-individual temporal variance heteroskedasticity
US10213586B2 (en) 2015-01-28 2019-02-26 Chrono Therapeutics Inc. Drug delivery methods and systems
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
GB2538698B (en) * 2015-04-02 2019-05-15 Cambridge Cognition Ltd Systems and methods for assessing cognitive function
US10610144B2 (en) * 2015-08-19 2020-04-07 Palo Alto Research Center Incorporated Interactive remote patient monitoring and condition management intervention system
KR102501837B1 (en) * 2015-11-09 2023-02-21 삼성전자주식회사 Signal feature extraction method and signal feature extraction apparatus
CN105491023B (en) * 2015-11-24 2020-10-27 国网智能电网研究院 Data isolation exchange and safety filtering method for power Internet of things
JP2020503950A (en) 2017-01-06 2020-02-06 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． Device and method for transdermal drug delivery
WO2018195312A1 (en) * 2017-04-20 2018-10-25 The Charles Stark Draper Laboratory, Inc. Implantable optical stimulation and detection leads for nervous tissue
CA3101966A1 (en) 2018-05-29 2019-12-05 Morningside Venture Investments Limited Drug delivery methods and systems
GB2620384A (en) 2022-07-01 2024-01-10 Neuronostics Ltd Method and system for estimating dynamic seizure likelihood

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035338A1 (en) * 1999-12-01 2002-03-21 Dear Stephen P. Epileptic seizure detection and prediction by self-similar methods
US20030144829A1 (en) * 2002-01-25 2003-07-31 Geatz Michael W. System and method for sensing and evaluating physiological parameters and modeling an adaptable predictive analysis for symptoms management

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3498287A (en) * 1966-04-28 1970-03-03 Neural Models Ltd Intelligence testing and signal analyzing means and method employing zero crossing detection
US3863625A (en) * 1973-11-02 1975-02-04 Us Health Epileptic seizure warning system
US4505275A (en) * 1977-09-15 1985-03-19 Wu Chen Treatment method and instrumentation system
US4566464A (en) * 1981-07-27 1986-01-28 Piccone Vincent A Implantable epilepsy monitor apparatus
US4494950A (en) * 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
US4573481A (en) * 1984-06-25 1986-03-04 Huntington Institute Of Applied Research Implantable electrode array
US5047930A (en) * 1987-06-26 1991-09-10 Nicolet Instrument Corporation Method and system for analysis of long term physiological polygraphic recordings
GB8729899D0 (en) * 1987-12-22 1988-02-03 Royal Postgrad Med School Method & apparatus for analysing electro-encephalogram
US4903702A (en) * 1988-10-17 1990-02-27 Ad-Tech Medical Instrument Corporation Brain-contact for sensing epileptogenic foci with improved accuracy
US5697369A (en) * 1988-12-22 1997-12-16 Biofield Corp. Method and apparatus for disease, injury and bodily condition screening or sensing
US4991582A (en) * 1989-09-22 1991-02-12 Alfred E. Mann Foundation For Scientific Research Hermetically sealed ceramic and metal package for electronic devices implantable in living bodies
US5292772A (en) * 1989-09-26 1994-03-08 Carter-Wallace, Inc. Method for the prevention and control of epileptic seizure associated with Lennox-Gastaut syndrome
US5082861A (en) * 1989-09-26 1992-01-21 Carter-Wallace, Inc. Method for the prevention and control of epileptic seizure associated with complex partial seizures
US5179950A (en) * 1989-11-13 1993-01-19 Cyberonics, Inc. Implanted apparatus having micro processor controlled current and voltage sources with reduced voltage levels when not providing stimulation
US5186170A (en) * 1989-11-13 1993-02-16 Cyberonics, Inc. Simultaneous radio frequency and magnetic field microprocessor reset circuit
US5097835A (en) * 1990-04-09 1992-03-24 Ad-Tech Medical Instrument Corporation Subdural electrode with improved lead connection
US5188104A (en) * 1991-02-01 1993-02-23 Cyberonics, Inc. Treatment of eating disorders by nerve stimulation
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5293879A (en) * 1991-09-23 1994-03-15 Vitatron Medical, B.V. System an method for detecting tremors such as those which result from parkinson's disease
US5392788A (en) * 1993-02-03 1995-02-28 Hudspeth; William J. Method and device for interpreting concepts and conceptual thought from brainwave data and for assisting for diagnosis of brainwave disfunction
DE4329898A1 (en) * 1993-09-04 1995-04-06 Marcus Dr Besson Wireless medical diagnostic and monitoring device
US5486999A (en) * 1994-04-20 1996-01-23 Mebane; Andrew H. Apparatus and method for categorizing health care utilization
US5707400A (en) * 1995-09-19 1998-01-13 Cyberonics, Inc. Treating refractory hypertension by nerve stimulation
US5704352A (en) * 1995-11-22 1998-01-06 Tremblay; Gerald F. Implantable passive bio-sensor
US5995868A (en) * 1996-01-23 1999-11-30 University Of Kansas System for the prediction, rapid detection, warning, prevention, or control of changes in activity states in the brain of a subject
US5611350A (en) * 1996-02-08 1997-03-18 John; Michael S. Method and apparatus for facilitating recovery of patients in deep coma
US5857978A (en) * 1996-03-20 1999-01-12 Lockheed Martin Energy Systems, Inc. Epileptic seizure prediction by non-linear methods
US6094598A (en) 1996-04-25 2000-07-25 Medtronics, Inc. Method of treating movement disorders by brain stimulation and drug infusion
US5716377A (en) * 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5683422A (en) 1996-04-25 1997-11-04 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
US5735814A (en) 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
US5711316A (en) * 1996-04-30 1998-01-27 Medtronic, Inc. Method of treating movement disorders by brain infusion
US5709214A (en) * 1996-05-02 1998-01-20 Enhanced Cardiology, Inc. PD2i electrophysiological analyzer
US5713923A (en) * 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion
US6104956A (en) * 1996-05-31 2000-08-15 Board Of Trustees Of Southern Illinois University Methods of treating traumatic brain injury by vagus nerve stimulation
US6070098A (en) * 1997-01-11 2000-05-30 Circadian Technologies, Inc. Method of and apparatus for evaluation and mitigation of microsleep events
US5876424A (en) * 1997-01-23 1999-03-02 Cardiac Pacemakers, Inc. Ultra-thin hermetic enclosure for implantable medical devices
US6042579A (en) * 1997-04-30 2000-03-28 Medtronic, Inc. Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain
US6016449A (en) * 1997-10-27 2000-01-18 Neuropace, Inc. System for treatment of neurological disorders
US6354299B1 (en) * 1997-10-27 2002-03-12 Neuropace, Inc. Implantable device for patient communication
US6647296B2 (en) * 1997-10-27 2003-11-11 Neuropace, Inc. Implantable apparatus for treating neurological disorders
US6042548A (en) * 1997-11-14 2000-03-28 Hypervigilant Technologies Virtual neurological monitor and method
US6208893B1 (en) * 1998-01-27 2001-03-27 Genetronics, Inc. Electroporation apparatus with connective electrode template
US6018682A (en) * 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
US7277758B2 (en) * 1998-08-05 2007-10-02 Neurovista Corporation Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder
US7599736B2 (en) * 2001-07-23 2009-10-06 Dilorenzo Biomedical, Llc Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
US7209787B2 (en) * 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US9113801B2 (en) * 1998-08-05 2015-08-25 Cyberonics, Inc. Methods and systems for continuous EEG monitoring
US7076307B2 (en) * 2002-05-09 2006-07-11 Boveja Birinder R Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders
US6356788B2 (en) * 1998-10-26 2002-03-12 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy for depression, migraine, neuropsychiatric disorders, partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6205359B1 (en) * 1998-10-26 2001-03-20 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy of partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6513046B1 (en) * 1999-12-15 2003-01-28 Tangis Corporation Storing and recalling information to augment human memories
US6341236B1 (en) * 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6176242B1 (en) * 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
US6356784B1 (en) * 1999-04-30 2002-03-12 Medtronic, Inc. Method of treating movement disorders by electrical stimulation and/or drug infusion of the pendunulopontine nucleus
US6312378B1 (en) * 1999-06-03 2001-11-06 Cardiac Intelligence Corporation System and method for automated collection and analysis of patient information retrieved from an implantable medical device for remote patient care
US6343226B1 (en) * 1999-06-25 2002-01-29 Neurokinetic Aps Multifunction electrode for neural tissue stimulation
US7300449B2 (en) * 1999-12-09 2007-11-27 Mische Hans A Methods and devices for the treatment of neurological and physiological disorders
US6510340B1 (en) * 2000-01-10 2003-01-21 Jordan Neuroscience, Inc. Method and apparatus for electroencephalography
US6768969B1 (en) * 2000-04-03 2004-07-27 Flint Hills Scientific, L.L.C. Method, computer program, and system for automated real-time signal analysis for detection, quantification, and prediction of signal changes
US6466822B1 (en) * 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6353754B1 (en) * 2000-04-24 2002-03-05 Neuropace, Inc. System for the creation of patient specific templates for epileptiform activity detection
US6442421B1 (en) * 2000-04-27 2002-08-27 Centre National De La Recherche Scientifique Method for the medical monitoring in real time of a patient from the analysis of electroencephalograms to characterize and differentiate between physiological or pathological conditions, and a method for anticipating epileptic seizures
US6505077B1 (en) * 2000-06-19 2003-01-07 Medtronic, Inc. Implantable medical device with external recharging coil electrical connection
US6687538B1 (en) * 2000-06-19 2004-02-03 Medtronic, Inc. Trial neuro stimulator with lead diagnostics
US7146217B2 (en) * 2000-07-13 2006-12-05 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a change in a neural-function of a patient
US6591138B1 (en) * 2000-08-31 2003-07-08 Neuropace, Inc. Low frequency neurostimulator for the treatment of neurological disorders
US20020077675A1 (en) * 2000-09-26 2002-06-20 Transneuronix, Inc. Minimally invasive surgery placement of stimulation leads in mediastinal structures
US6678548B1 (en) * 2000-10-20 2004-01-13 The Trustees Of The University Of Pennsylvania Unified probabilistic framework for predicting and detecting seizure onsets in the brain and multitherapeutic device
US6534693B2 (en) * 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
US6529774B1 (en) * 2000-11-09 2003-03-04 Neuropace, Inc. Extradural leads, neurostimulator assemblies, and processes of using them for somatosensory and brain stimulation
US7158833B2 (en) * 2000-11-28 2007-01-02 Neuropace, Inc. Ferrule for cranial implant
US6594524B2 (en) * 2000-12-12 2003-07-15 The Trustees Of The University Of Pennsylvania Adaptive method and apparatus for forecasting and controlling neurological disturbances under a multi-level control
US7177701B1 (en) * 2000-12-29 2007-02-13 Advanced Bionics Corporation System for permanent electrode placement utilizing microelectrode recording methods
US6609025B2 (en) * 2001-01-02 2003-08-19 Cyberonics, Inc. Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation
US6684105B2 (en) * 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US6810285B2 (en) * 2001-06-28 2004-10-26 Neuropace, Inc. Seizure sensing and detection using an implantable device
US6606521B2 (en) * 2001-07-09 2003-08-12 Neuropace, Inc. Implantable medical lead
US6832200B2 (en) * 2001-09-07 2004-12-14 Hewlett-Packard Development Company, L.P. Apparatus for closed-loop pharmaceutical delivery
US6662035B2 (en) * 2001-09-13 2003-12-09 Neuropace, Inc. Implantable lead connector assembly for implantable devices and methods of using it
JP2005518871A (en) * 2002-03-07 2005-06-30 バング・オ・オルフセン・メディコム・アクティーゼルスカブ Medical dispenser, blister card used in dispenser and method of dispensing medication
US6990372B2 (en) * 2002-04-11 2006-01-24 Alfred E. Mann Foundation For Scientific Research Programmable signal analysis device for detecting neurological signals in an implantable device
US7177698B2 (en) * 2002-06-28 2007-02-13 Advanced Bionics Corporation Telemetry system for use with microstimulator
US7209861B2 (en) * 2002-07-12 2007-04-24 Ut-Battelle Llc Methods for improved forewarning of critical events across multiple data channels
US7007191B2 (en) * 2002-08-23 2006-02-28 Lsi Logic Corporation Method and apparatus for identifying one or more devices having faults in a communication loop
US7277748B2 (en) * 2002-09-13 2007-10-02 Neuropace, Inc. Spatiotemporal pattern recognition for neurological event detection and prediction in an implantable device
FR2845883B1 (en) * 2002-10-18 2005-08-05 Centre Nat Rech Scient METHOD AND DEVICE FOR REAL-TIME MEDICAL OR COGNITIVE FOLLOW-UP BY ANALYZING BRAIN ELECTROMAGNETIC ACTIVITY OF AN INDIVIDUAL, APPLYING THE METHOD FOR CHARACTERIZING AND DIFFERENTIATING PHYSIOLOGICAL OR PATHOLOGICAL CONDITIONS
US20050049649A1 (en) * 2002-10-21 2005-03-03 The Cleveland Clinic Foundation Electrical stimulation of the brain
US20050010261A1 (en) * 2002-10-21 2005-01-13 The Cleveland Clinic Foundation Application of stimulus to white matter to induce a desired physiological response
AU2004238259B2 (en) * 2003-05-06 2010-02-18 Covidien Lp System and method of assessment of the efficacy of treatment of neurological disorders using the electroencephalogram
US7454251B2 (en) * 2003-05-29 2008-11-18 The Cleveland Clinic Foundation Excess lead retaining and management devices and methods of using same
US20050021128A1 (en) * 2003-07-24 2005-01-27 Medtronic Vascular, Inc. Compliant, porous, rolled stent
US20050033369A1 (en) * 2003-08-08 2005-02-10 Badelt Steven W. Data Feedback loop for medical therapy adjustment
US7680537B2 (en) * 2003-08-18 2010-03-16 Cardiac Pacemakers, Inc. Therapy triggered by prediction of disordered breathing
US20050059867A1 (en) * 2003-09-13 2005-03-17 Cheng Chung Yuan Method for monitoring temperature of patient
US7174212B1 (en) * 2003-12-10 2007-02-06 Pacesetter, Inc. Implantable medical device having a casing providing high-speed telemetry
US7881798B2 (en) * 2004-03-16 2011-02-01 Medtronic Inc. Controlling therapy based on sleep quality
JP2008506464A (en) * 2004-07-15 2008-03-06 ノーススター ニューロサイエンス インコーポレイテッド System and method for enhancing or influencing neural stimulation efficiency and / or efficacy
JP4500126B2 (en) * 2004-08-02 2010-07-14 富士重工業株式会社 Fault diagnosis device for yaw rate sensor
US7769472B2 (en) * 2005-07-29 2010-08-03 Medtronic, Inc. Electrical stimulation lead with conformable array of electrodes
US20070025910A1 (en) * 2005-07-29 2007-02-01 Norenberg Jeffrey P Anticancer therapy
US20070027367A1 (en) * 2005-08-01 2007-02-01 Microsoft Corporation Mobile, personal, and non-intrusive health monitoring and analysis system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035338A1 (en) * 1999-12-01 2002-03-21 Dear Stephen P. Epileptic seizure detection and prediction by self-similar methods
US20030144829A1 (en) * 2002-01-25 2003-07-31 Geatz Michael W. System and method for sensing and evaluating physiological parameters and modeling an adaptable predictive analysis for symptoms management

Also Published As

Publication number Publication date
US20070149952A1 (en) 2007-06-28
WO2007079191A2 (en) 2007-07-12
EP1977389A2 (en) 2008-10-08
EP1977389A4 (en) 2012-07-18

Similar Documents

Publication Publication Date Title
WO2007079191A3 (en) System for characterizing a patient's propensity for a neurological event
WO2007056300A3 (en) Methods and compositions for the treatment of brain reward system disorders by combination therapy
WO2007079181A3 (en) Methods and systems for recommending an action to a patient for managing epilepsy and other neurological disorders
WO2006047516A3 (en) Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
WO2008076754A3 (en) Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
WO2003093499A3 (en) Therapeutic use of selective pde10 inhibitors
EP1250923A3 (en) Use of selective PDE10 inhibitors for the treatment of central nervous system disorders
EP3552607A3 (en) Imidazopyrazine syk inhibitors
WO2003077972A3 (en) Implantable drug delivery system
AU2003239916A1 (en) System and method for reliable delivery of event information
EP2213285A3 (en) Use of sphingosine-1-phosphate (S1P) receptor agonists in combination with a second agent for the treatment of brain degenerative diseases
AU2003223171A1 (en) System and method for single event authorization control of transactions
WO2008064340A3 (en) System for seizure suppression
FR2747301B1 (en) IMPLANTABLE DEVICE FOR MAINTAINING OR RE-ESTABLISHING THE NORMAL PASSAGE SECTION OF A BODY DUCT, AS WELL AS A SYSTEM FOR ITS PLACEMENT
WO2006106311A3 (en) Combination treatment methods for treating sex-hormone dependent disease and fertility treatment
AU4059900A (en) Improved conjunctival inserts for topical delivery of medication or lubrication
EP1744708A4 (en) Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
CA2391808A1 (en) Method for treatment of symptoms of central nervous system disorders
AU2003291239A1 (en) System and method for assessing the functional ability or medical condition of an actor
Galvis et al. Expression of nicotinic acetylcholine receptors on murine alveolar macrophages
WO2007051785A3 (en) Use of sdf-1 for the treatment and/or prevention of neurological diseases
WO2001098279A3 (en) Bis-arylsulfones
WO2006103660A3 (en) Wearable soothing system
WO2004062563A3 (en) Methods for screening for therapeutic agents that are useful in the treatment of oxytocin and vasopressin-related disorders
AU2003251697A1 (en) Method for event synchronisation, especially for processors of fault-tolerant systems

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006848288

Country of ref document: EP