WO2007073549A3 - Coated embolic coils with fibers - Google Patents

Coated embolic coils with fibers Download PDF

Info

Publication number
WO2007073549A3
WO2007073549A3 PCT/US2006/062243 US2006062243W WO2007073549A3 WO 2007073549 A3 WO2007073549 A3 WO 2007073549A3 US 2006062243 W US2006062243 W US 2006062243W WO 2007073549 A3 WO2007073549 A3 WO 2007073549A3
Authority
WO
WIPO (PCT)
Prior art keywords
fibers
coil body
embolic
fiber bundles
coils
Prior art date
Application number
PCT/US2006/062243
Other languages
French (fr)
Other versions
WO2007073549A2 (en
Inventor
Marcia S Buiser
Ashley Seehusen
Christopher Nardone
Paul D Dicarlo
Original Assignee
Boston Scient Scimed Inc
Marcia S Buiser
Ashley Seehusen
Christopher Nardone
Paul D Dicarlo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/311,617 external-priority patent/US8101197B2/en
Priority claimed from US11/430,602 external-priority patent/US8152839B2/en
Application filed by Boston Scient Scimed Inc, Marcia S Buiser, Ashley Seehusen, Christopher Nardone, Paul D Dicarlo filed Critical Boston Scient Scimed Inc
Publication of WO2007073549A2 publication Critical patent/WO2007073549A2/en
Publication of WO2007073549A3 publication Critical patent/WO2007073549A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/12145Coils or wires having a pre-set deployed three-dimensional shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • A61B17/1215Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D7/00Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
    • B05D7/20Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526Methods of manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00867Material properties shape memory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00898Material properties expandable upon contact with fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12063Details concerning the detachment of the occluding device from the introduction device electrolytically detachable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/114Nitric oxide, i.e. NO
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/36Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00Processes for applying liquids or other fluent materials
    • B05D1/18Processes for applying liquids or other fluent materials performed by dipping

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Coils, such as embolic coils, and related methods, devices, and compositions, arc disclosed. It shows the primary shape of an embolic coil (10) that includes an embolic coil body (12), fiber bundles (18) attached to coil body (12), and a coating (20). Coil body (12) is formed of windings (e.g., windings 14, 15, and 16) of a wire (17) (e.g., a platinum wire). Fiber bundles (18) are formed of fibers (22) (e.g., polyester fibers). Coating (20) is disposed on the exterior surface (24) of coil body (12), and encapsulates fiber bundles (18). Embolic coil (10) may be used, for example, in an embolization procedure, and/or may be used to deliver one or more therapeutic agents to a target site.
PCT/US2006/062243 2005-12-19 2006-12-18 Coated embolic coils with fibers WO2007073549A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US11/311,617 2005-12-19
US11/311,617 US8101197B2 (en) 2005-12-19 2005-12-19 Forming coils
US11/430,602 US8152839B2 (en) 2005-12-19 2006-05-09 Embolic coils
US11/430,602 2006-05-09
US11/458,156 2006-07-18
US11/458,156 US20070142859A1 (en) 2005-12-19 2006-07-18 Embolic coils

Publications (2)

Publication Number Publication Date
WO2007073549A2 WO2007073549A2 (en) 2007-06-28
WO2007073549A3 true WO2007073549A3 (en) 2007-10-18

Family

ID=38189156

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/062243 WO2007073549A2 (en) 2005-12-19 2006-12-18 Coated embolic coils with fibers

Country Status (2)

Country Link
US (1) US20070142859A1 (en)
WO (1) WO2007073549A2 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US20070078480A1 (en) * 2005-10-04 2007-04-05 Boston Scientific Scimed, Inc. Self-expanding biodegradable or water-soluble vaso-occlusive devices
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US8398696B2 (en) * 2007-03-01 2013-03-19 Boston Scientific Scimed, Inc. Microcatheter introducer sheath
CA2679112C (en) * 2007-03-05 2015-08-11 Boston Scientific Limited Deploying embolic coils
WO2008109394A2 (en) * 2007-03-08 2008-09-12 Boston Scientific Limited Systems and methods for delivering a detachable implantable device
US8500773B2 (en) * 2007-08-01 2013-08-06 Boston Scientific Scimed, Inc. Spring detach joint for delivering a detachable implantable device
US9907555B2 (en) * 2007-08-09 2018-03-06 Boston Scientific Scimed, Inc. Guided detachable interlock and method of use
US7901704B2 (en) * 2007-08-21 2011-03-08 Boston Scientific Scimed, Inc. Embolization
US20090099592A1 (en) * 2007-10-15 2009-04-16 Boston Scientific Scimed, Inc. Detachable Interlock Systems and Methods of Use
WO2009094025A1 (en) * 2008-01-23 2009-07-30 Vascucorp Llc Intraluminal detachable biodegradeable thrombogenic catheter device and method of use
CA2735748C (en) 2008-09-04 2017-08-29 Curaseal Inc. Inflatable devices for enteric fistula treatment
US8790364B2 (en) * 2008-12-10 2014-07-29 Boston Scientific Scimed, Inc. Introducer sheath for use with an embolic coil device and methods for making and using the same
EP2521497A4 (en) * 2010-01-08 2015-07-01 Neurosurj Res & Dev Llc Method and apparatus for cutting embolic coils
CN103874466B (en) 2011-06-16 2016-10-05 库拉希尔公司 Device and correlation technique for fistula treatment
JP6127042B2 (en) 2011-06-17 2017-05-10 キュラシール インコーポレイテッド Device and method for fistula treatment
AU2015268569B2 (en) * 2011-08-05 2017-06-08 W. L. Gore & Associates, Inc. Polymer-based occlusion devices and systems
US20130035665A1 (en) * 2011-08-05 2013-02-07 W. L. Gore & Associates, Inc. Polymer-Based Occlusion Devices, Systems and Methods
US9277905B2 (en) 2012-08-02 2016-03-08 W. L. Gore & Associates, Inc. Space-filling device
WO2014164496A1 (en) * 2013-03-11 2014-10-09 Ferry Steven J Flat wound detachable embolization coil
US9192389B2 (en) 2013-03-13 2015-11-24 Cook Medical Technologies Llc Occluding device and method of manufacturing occluding devices
US10675039B2 (en) 2013-03-15 2020-06-09 Embo Medical Limited Embolisation systems
CN112716556A (en) * 2013-03-15 2021-04-30 恩波医疗有限公司 Embolization system
US10660645B2 (en) * 2013-03-15 2020-05-26 Embo Medical Limited Embolization systems
US20160066921A1 (en) * 2014-02-21 2016-03-10 Neuravi Limited DEVICE AND METHOD FOR ENDOVASCULAR TREATMENT OF ANEURYSMS USING EMBOLIC ePTFE
US10722241B2 (en) * 2014-11-24 2020-07-28 Boston Scientific Scimed, Inc. Nitinol occlusion plug
JP6708200B2 (en) * 2015-03-03 2020-06-10 株式会社カネカメディックス Vascular embolization device and method for manufacturing the same
US10335154B2 (en) * 2015-09-10 2019-07-02 Ikonano Venture Partners, Llc Polymeric electrospun embolization device and methods of use
US11172933B2 (en) * 2017-08-29 2021-11-16 Covidien Lp Methods and devices for altering lung volume
IT201800002332A1 (en) * 2018-02-02 2019-08-02 Amista Pietro INTRANEURISMATIC DEVICE FOR THE TREATMENT OF ANEURISMS
CN112153946A (en) 2018-04-04 2020-12-29 因库麦迪斯有限公司 Embolic device with improved neck coverage
US20200383689A1 (en) * 2019-06-05 2020-12-10 Endoshape, Inc. Systems, devices and methods for improved occlusion and delivery
WO2022014632A1 (en) * 2020-07-16 2022-01-20 テルモ株式会社 Medical instrument set, delivery system, and embolus delivery medical system
US20220296249A1 (en) * 2021-03-16 2022-09-22 Rhode Island Hospital Endovascular coil device for embolization of blood vessels
CN115211924B (en) * 2022-07-26 2024-04-05 苏州中天医疗器械科技有限公司 Embolic coil, embolic coil assembly and method of use thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002089865A2 (en) * 2001-05-04 2002-11-14 Concentric Medical Coated combination vaso-occlusive device
WO2004091712A2 (en) * 2003-04-09 2004-10-28 Scimed Life Systems, Inc. Bioactive components for incorporation with vaso-occlusive members
US20050004598A1 (en) * 2003-07-03 2005-01-06 Cook Incorporated Occluding device and method of occluding fluid flow through a body vessel
EP1584298A1 (en) * 2004-04-08 2005-10-12 Cordis Neurovascular, Inc. Activatable bioactive vascular occlusive device comprising fibers
WO2005113035A2 (en) * 2004-05-21 2005-12-01 Micro Therapeutics, Inc. Metallic coils enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of a body cavity
WO2007041131A2 (en) * 2005-09-30 2007-04-12 Cook Incorporated Coated vaso-occlusion device

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076640A (en) * 1975-02-24 1978-02-28 Xerox Corporation Preparation of spheroidized particles
GB1591924A (en) * 1976-10-25 1981-07-01 Berger Jenson & Nicholson Ltd Polymer aggregates
US4900303A (en) * 1978-03-10 1990-02-13 Lemelson Jerome H Dispensing catheter and method
US4243794A (en) * 1978-10-10 1981-01-06 Minnesota Mining And Manufacturing Company Mixture of rough and spheroidized resin particles
US4198318A (en) * 1978-11-24 1980-04-15 Conoco, Inc. Production of high strength alumina spheres by hydrogelling corresponding slurries
US4246208A (en) * 1979-03-22 1981-01-20 Xerox Corporation Dust-free plasma spheroidization
HU184722B (en) * 1980-02-18 1984-10-29 Laszlo Lazar Therapeutically suitable silicone rubber mixture and therapeuticaid
DE3031737A1 (en) * 1980-08-22 1982-04-01 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING PEARL POLYMERISATS OF UNIFORM PARTICLE SIZE
CA1166413A (en) * 1980-10-30 1984-05-01 Edward E. Timm Process and apparatus for preparing uniform size polymer beads
US4657756A (en) * 1980-11-17 1987-04-14 Schering Aktiengesellschaft Microbubble precursors and apparatus for their production and use
US4442843A (en) * 1980-11-17 1984-04-17 Schering, Ag Microbubble precursors and methods for their production and use
US4428869A (en) * 1981-08-20 1984-01-31 International Flavors & Fragrances Inc. Cologne consisting of microcapsule suspension
CA1225585A (en) * 1983-06-30 1987-08-18 Maria T. Litvinova Composition for embolization of blood vessels
US4492720A (en) * 1983-11-15 1985-01-08 Benjamin Mosier Method of preparing microspheres for intravascular delivery
US4573967A (en) * 1983-12-06 1986-03-04 Eli Lilly And Company Vacuum vial infusion system
FR2566384B1 (en) * 1984-06-21 1986-09-05 Saint Gobain Vitrage IMPROVEMENTS IN TECHNIQUES FOR THE PRODUCTION OF GLASS MICROSPHERES
GB8419708D0 (en) * 1984-08-02 1984-09-05 Shell Int Research Preparation of silica spheres
US4789501A (en) * 1984-11-19 1988-12-06 The Curators Of The University Of Missouri Glass microspheres
US5106903A (en) * 1984-12-17 1992-04-21 Lehigh University Preparation of large particle size monodisperse latexes
JPS61293911A (en) * 1985-06-24 1986-12-24 Teisan Seiyaku Kk Sustained release preparation
SE459005B (en) * 1985-07-12 1989-05-29 Aake Rikard Lindahl SET TO MANUFACTURE SPHERICAL POLYMER PARTICLES
JPS62169723A (en) * 1986-01-22 1987-07-25 Teisan Seiyaku Kk Sustained release preparation
JPS63113429A (en) * 1986-05-21 1988-05-18 Toray Ind Inc Organic nonlinear optical material
US5292814A (en) * 1987-04-29 1994-03-08 Ernst Bayer Process for the preparation of monodispersed polymer beads
US4795741A (en) * 1987-05-06 1989-01-03 Biomatrix, Inc. Compositions for therapeutic percutaneous embolization and the use thereof
US4819637A (en) * 1987-09-01 1989-04-11 Interventional Therapeutics Corporation System for artificial vessel embolization and devices for use therewith
US4804366A (en) * 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
US4981625A (en) * 1988-03-14 1991-01-01 California Institute Of Technology Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops
FR2634376B1 (en) * 1988-07-21 1992-04-17 Farmalyoc NOVEL SOLID AND POROUS UNIT FORM COMPRISING MICROPARTICLES AND / OR NANOPARTICLES, AS WELL AS ITS PREPARATION
US4994069A (en) * 1988-11-02 1991-02-19 Target Therapeutics Vaso-occlusion coil and method
FR2641692A1 (en) * 1989-01-17 1990-07-20 Nippon Zeon Co Plug for closing an opening for a medical application, and device for the closure plug making use thereof
US5091205A (en) * 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
GB8905934D0 (en) * 1989-03-15 1989-04-26 Dow Europ Sa A process for preparing adsorptive porous resin beads
CA2017570C (en) * 1989-05-31 2000-12-19 James R. Gross Porous structure of an absorbent polymer
US5007940A (en) * 1989-06-09 1991-04-16 American Medical Systems, Inc. Injectable polymeric bodies
US5190760A (en) * 1989-07-08 1993-03-02 Coopers Animal Health Limited Solid pharmaceutical composition
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5122136A (en) * 1990-03-13 1992-06-16 The Regents Of The University Of California Endovascular electrolytically detachable guidewire tip for the electroformation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
JPH03297475A (en) * 1990-04-16 1991-12-27 Ken Ishihara Controlling method for emission of medicine by means of resonance sound wave
JP2514087Y2 (en) * 1990-05-25 1996-10-16 幸三 牧田 Balloon with detachable double-sided check valve
US5108407A (en) * 1990-06-08 1992-04-28 Rush-Presbyterian St. Luke's Medical Center Method and apparatus for placement of an embolic coil
EP0470569B1 (en) * 1990-08-08 1995-11-22 Takeda Chemical Industries, Ltd. Intravascular embolizing agent containing angiogenesis inhibiting substance
US5484584A (en) * 1990-10-02 1996-01-16 Board Of Regents, The University Of Texas System Therapeutic and diagnostic use of modified polymeric microcapsules
US5149543A (en) * 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
DE69220317T2 (en) * 1991-10-01 1997-10-16 Takeda Chemical Industries Ltd Microparticle summary for extended release and manufacture of the same
JP3356447B2 (en) * 1991-10-16 2002-12-16 テルモ株式会社 Vascular lesion embolic material composed of dried polymer gel
US5290310A (en) * 1991-10-30 1994-03-01 Howmedica, Inc. Hemostatic implant introducer
DK0617594T3 (en) * 1991-12-12 1998-02-02 Target Therapeutics Inc Separate ejector body lock coil construction with interlocking coupling
DE69226203T2 (en) * 1991-12-20 1998-12-10 Allied Signal Inc MATERIALS WITH LOW DENSITY AND HIGH SPECIFIC SURFACE AND ARTICLES MOLDED THEREOF FOR USE IN METAL RECOVERY
US5480644A (en) * 1992-02-28 1996-01-02 Jsf Consultants Ltd. Use of injectable biomaterials for the repair and augmentation of the anal sphincters
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
US5292332A (en) * 1992-07-27 1994-03-08 Lee Benjamin I Methods and device for percutanceous sealing of arterial puncture sites
US5807323A (en) * 1992-08-13 1998-09-15 Science Incorporated Mixing and delivery syringe assembly
US5512604A (en) * 1992-08-28 1996-04-30 The Dow Chemical Company Porous copolymers having a cellular polymeric structure suitable for preparing ion-exchange resins and adsorbents
CA2144749A1 (en) * 1992-09-16 1994-03-31 Jo Klaveness Improvements in or relating to contrast agents
USRE37117E1 (en) * 1992-09-22 2001-03-27 Target Therapeutics, Inc. Detachable embolic coil assembly using interlocking clasps and method of use
US5350397A (en) * 1992-11-13 1994-09-27 Target Therapeutics, Inc. Axially detachable embolic coil assembly
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
US5382260A (en) * 1992-10-30 1995-01-17 Interventional Therapeutics Corp. Embolization device and apparatus including an introducer cartridge and method for delivering the same
US5288763A (en) * 1992-12-23 1994-02-22 The Johns Hopkins University School Of Medicine Porous, polymer beads and process of their preparation
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
US5397303A (en) * 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
US5398851A (en) * 1993-08-06 1995-03-21 River Medical, Inc. Liquid delivery device
EP1258262A3 (en) * 1993-10-28 2002-12-18 Medrad, Inc. Total system for contrast delivery
WO1995019841A1 (en) * 1994-01-21 1995-07-27 Bruce Nathaniel Gray Particulate material
US5534589A (en) * 1994-05-04 1996-07-09 Minnesota Mining And Manufacturing Company Repulpable plastic films
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
DK175166B1 (en) * 1995-01-03 2004-06-21 Cook William Europ Method of manufacturing an assembly for placing an embolization coil in the vascular system and such assembly as well as an apparatus for advancing the assembly
CA2207667A1 (en) * 1995-01-27 1996-08-01 Scimed Life Systems, Inc. Embolizing system
US6179817B1 (en) * 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US5876372A (en) * 1995-03-22 1999-03-02 Abbott Laboratories Syringe system accomodating seperate prefilled barrels for two constituents
US5877224A (en) * 1995-07-28 1999-03-02 Rutgers, The State University Of New Jersey Polymeric drug formulations
US5888546A (en) * 1995-08-28 1999-03-30 The Regents Of The University Of California Embolic material for endovascular occlusion of abnormal vasculature and method for using the same
US5702361A (en) * 1996-01-31 1997-12-30 Micro Therapeutics, Inc. Method for embolizing blood vessels
US5895398A (en) * 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
US5855615A (en) * 1996-06-07 1999-01-05 Menlo Care, Inc. Controller expansion sphincter augmentation media
US5741331A (en) * 1996-07-29 1998-04-21 Corvita Corporation Biostable elastomeric polymers having quaternary carbons
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
AU7953698A (en) * 1997-06-13 1998-12-30 Micro Therapeutics, Inc. Contoured syringe and novel luer hub and methods for embolizing blood ve ssels
FR2784580B1 (en) * 1998-10-16 2004-06-25 Biosepra Inc POLYVINYL-ALCOHOL MICROSPHERES AND METHODS OF MAKING THE SAME
US6790218B2 (en) * 1999-12-23 2004-09-14 Swaminathan Jayaraman Occlusive coil manufacture and delivery
KR100335866B1 (en) * 2000-01-06 2002-05-10 박호군 Microspheric Embolic Materials Having Duel Structure of Poly(Vinyl Acetate) Core/Poly(Vinyl Alcohol) Shell, and Method for Preparing The Same
US6355275B1 (en) * 2000-06-23 2002-03-12 Carbon Medical Technologies, Inc. Embolization using carbon coated microparticles
AUPR098300A0 (en) * 2000-10-25 2000-11-16 Sirtex Medical Limited Polymer based radionuclide containing microspheres
US6706274B2 (en) * 2001-01-18 2004-03-16 Scimed Life Systems, Inc. Differential delivery of nitric oxide
US20030032935A1 (en) * 2001-08-10 2003-02-13 Scimed Life Systems, Inc. Packages facilitating convenient mixing and delivery of liquids
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
AU2003241515A1 (en) * 2002-05-20 2003-12-12 Orbus Medical Technologies Inc. Drug eluting implantable medical device
US7906148B2 (en) * 2003-07-31 2011-03-15 Boston Scientific Scimed, Inc. Latex medical articles for release of antimicrobial agents
US20050037047A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices comprising spray dried microparticles
US20060045900A1 (en) * 2004-08-27 2006-03-02 Robert Richard Embolization
US20070004973A1 (en) * 2005-06-15 2007-01-04 Tan Sharon M L Tissue treatment methods

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002089865A2 (en) * 2001-05-04 2002-11-14 Concentric Medical Coated combination vaso-occlusive device
WO2004091712A2 (en) * 2003-04-09 2004-10-28 Scimed Life Systems, Inc. Bioactive components for incorporation with vaso-occlusive members
US20050004598A1 (en) * 2003-07-03 2005-01-06 Cook Incorporated Occluding device and method of occluding fluid flow through a body vessel
EP1584298A1 (en) * 2004-04-08 2005-10-12 Cordis Neurovascular, Inc. Activatable bioactive vascular occlusive device comprising fibers
WO2005113035A2 (en) * 2004-05-21 2005-12-01 Micro Therapeutics, Inc. Metallic coils enlaced with biological or biodegradable or synthetic polymers or fibers for embolization of a body cavity
WO2007041131A2 (en) * 2005-09-30 2007-04-12 Cook Incorporated Coated vaso-occlusion device

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