WO2007062036A3 - Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent - Google Patents

Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent Download PDF

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Publication number
WO2007062036A3
WO2007062036A3 PCT/US2006/045055 US2006045055W WO2007062036A3 WO 2007062036 A3 WO2007062036 A3 WO 2007062036A3 US 2006045055 W US2006045055 W US 2006045055W WO 2007062036 A3 WO2007062036 A3 WO 2007062036A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical device
therapeutic agent
implantable medical
device coatings
biodegradable elastomer
Prior art date
Application number
PCT/US2006/045055
Other languages
French (fr)
Other versions
WO2007062036A2 (en
Inventor
Priscilla T Reyes
Patrick H Ruane
Waleska Perez-Segarra
Original Assignee
Med Inst Inc
Priscilla T Reyes
Patrick H Ruane
Waleska Perez-Segarra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Med Inst Inc, Priscilla T Reyes, Patrick H Ruane, Waleska Perez-Segarra filed Critical Med Inst Inc
Publication of WO2007062036A2 publication Critical patent/WO2007062036A2/en
Publication of WO2007062036A3 publication Critical patent/WO2007062036A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

Abstract

A coated medical device, such as a stent, that elutes a therapeutic agent in a controlled manner is provided. The medical device may be coated with a layer of therapeutic agent and a layer of bioabsorbable elastomer over the layer of therapeutic agent. Methods of manufacturing a coated medical device and of coating a medical device are also provided.
PCT/US2006/045055 2005-11-21 2006-11-21 Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent WO2007062036A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73847505P 2005-11-21 2005-11-21
US60/738,475 2005-11-21

Publications (2)

Publication Number Publication Date
WO2007062036A2 WO2007062036A2 (en) 2007-05-31
WO2007062036A3 true WO2007062036A3 (en) 2008-03-27

Family

ID=38067858

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/045055 WO2007062036A2 (en) 2005-11-21 2006-11-21 Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent

Country Status (1)

Country Link
WO (1) WO2007062036A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685433B2 (en) 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
CN113260388A (en) * 2019-01-30 2021-08-13 百多力股份公司 Covered stent for local drug delivery

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000045744A1 (en) * 1999-02-03 2000-08-10 Boston Scientific Limited Surface protection method for stents and balloon catheters for drug delivery
US6299604B1 (en) * 1998-08-20 2001-10-09 Cook Incorporated Coated implantable medical device
WO2005004946A1 (en) * 2003-06-30 2005-01-20 Boston Scientific Limited Medical devices and methods for inhibiting smooth muscle cell proliferation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795475A (en) 1985-08-09 1989-01-03 Walker Michael M Prosthesis utilizing salt-forming oxyacids for bone fixation
IL76079A (en) 1985-08-13 1991-03-10 Univ Ramot Collagen implants
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
FR2696463B1 (en) 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Process for obtaining 10-deacetyl baccatin III.
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
EP0741585A1 (en) 1994-01-21 1996-11-13 Brown University Research Foundation Biocompatible implants
US5876743A (en) 1995-03-21 1999-03-02 Den-Mat Corporation Biocompatible adhesion in tissue repair
JP3318578B2 (en) 1995-05-26 2002-08-26 サーモディックス，インコーポレイティド Methods for promoting endothelialization and implantable products

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299604B1 (en) * 1998-08-20 2001-10-09 Cook Incorporated Coated implantable medical device
WO2000045744A1 (en) * 1999-02-03 2000-08-10 Boston Scientific Limited Surface protection method for stents and balloon catheters for drug delivery
WO2005004946A1 (en) * 2003-06-30 2005-01-20 Boston Scientific Limited Medical devices and methods for inhibiting smooth muscle cell proliferation

Also Published As

Publication number Publication date
WO2007062036A2 (en) 2007-05-31

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