WO2007056316A3 - Injectable physiological temperature setting cement composites for spinal fusion and related method thereof - Google Patents

Injectable physiological temperature setting cement composites for spinal fusion and related method thereof Download PDF

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Publication number
WO2007056316A3
WO2007056316A3 PCT/US2006/043240 US2006043240W WO2007056316A3 WO 2007056316 A3 WO2007056316 A3 WO 2007056316A3 US 2006043240 W US2006043240 W US 2006043240W WO 2007056316 A3 WO2007056316 A3 WO 2007056316A3
Authority
WO
WIPO (PCT)
Prior art keywords
composites
spinal fusion
temperature setting
related method
physiological temperature
Prior art date
Application number
PCT/US2006/043240
Other languages
French (fr)
Other versions
WO2007056316A2 (en
Inventor
Cato T Laurencin
Swaminathan Sethuraman
Trevor T Starnes
Saadiq El-Amin
Lakshmi Sreedharan Nair
Harry R Allcock
Anurima Singh
Paul Brown
Jacqueline Sturgeon
Original Assignee
Univ Virginia
Penn State Res Found
Cato T Laurencin
Swaminathan Sethuraman
Trevor T Starnes
Saadiq El-Amin
Lakshmi Sreedharan Nair
Harry R Allcock
Anurima Singh
Paul Brown
Jacqueline Sturgeon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia, Penn State Res Found, Cato T Laurencin, Swaminathan Sethuraman, Trevor T Starnes, Saadiq El-Amin, Lakshmi Sreedharan Nair, Harry R Allcock, Anurima Singh, Paul Brown, Jacqueline Sturgeon filed Critical Univ Virginia
Publication of WO2007056316A2 publication Critical patent/WO2007056316A2/en
Publication of WO2007056316A3 publication Critical patent/WO2007056316A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Abstract

Biodegradable composites and methods for the replacement of bone are described. The composites are made up of a polyphosphazene and an osteoconductive material. The composites are free flowing upon mixing and then later set under physiological tempertures. Methods for using the composites for fusing vertebrae during spinal fusion procedures are also described.
PCT/US2006/043240 2005-11-04 2006-11-06 Injectable physiological temperature setting cement composites for spinal fusion and related method thereof WO2007056316A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73396705P 2005-11-04 2005-11-04
US60/733,967 2005-11-04
US84486306P 2006-09-15 2006-09-15
US60/844,863 2006-09-15

Publications (2)

Publication Number Publication Date
WO2007056316A2 WO2007056316A2 (en) 2007-05-18
WO2007056316A3 true WO2007056316A3 (en) 2009-05-07

Family

ID=38023907

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/043240 WO2007056316A2 (en) 2005-11-04 2006-11-06 Injectable physiological temperature setting cement composites for spinal fusion and related method thereof

Country Status (1)

Country Link
WO (1) WO2007056316A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
WO2009054854A1 (en) * 2007-10-26 2009-04-30 Celonova Biosciences, Inc. Loadable polymeric particles for bone augmentation and methods of preparing and using the same
US8877220B2 (en) * 2010-08-05 2014-11-04 Collagen Matrix, Inc. Self-expandable biopolymer-mineral composite
AT515955B1 (en) * 2014-06-16 2016-08-15 Universität Linz Polymer structure and three-dimensional framework for tissue engineering
CN112662152B (en) * 2020-12-23 2022-07-05 山西生物质新材料产业研究院有限公司 Polylactic acid-based degradable composite material, preparation method and application of polylactic acid-based degradable composite material as mulching film

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331312B1 (en) * 1995-05-19 2001-12-18 Etex Corporation Bioresorbable ceramic composites
US6616698B2 (en) * 1998-12-14 2003-09-09 Osteotech, Inc. Bone graft and guided bone regeneration method
US6811776B2 (en) * 2000-12-27 2004-11-02 The Regents Of The University Of Michigan Process for ex vivo formation of mammalian bone and uses thereof
US20050112349A1 (en) * 2003-09-10 2005-05-26 Laurencin Cato T. Polymeric nanofibers for tissue engineering and drug delivery
US7211136B2 (en) * 2001-10-24 2007-05-01 Pentron Clinical Technologies, Llc Dental filling material

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331312B1 (en) * 1995-05-19 2001-12-18 Etex Corporation Bioresorbable ceramic composites
US6616698B2 (en) * 1998-12-14 2003-09-09 Osteotech, Inc. Bone graft and guided bone regeneration method
US6811776B2 (en) * 2000-12-27 2004-11-02 The Regents Of The University Of Michigan Process for ex vivo formation of mammalian bone and uses thereof
US7211136B2 (en) * 2001-10-24 2007-05-01 Pentron Clinical Technologies, Llc Dental filling material
US20050112349A1 (en) * 2003-09-10 2005-05-26 Laurencin Cato T. Polymeric nanofibers for tissue engineering and drug delivery

Also Published As

Publication number Publication date
WO2007056316A2 (en) 2007-05-18

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