WO2007038160A3 - Pulsed cavitational ultrasound therapy - Google Patents

Pulsed cavitational ultrasound therapy Download PDF

Info

Publication number
WO2007038160A3
WO2007038160A3 PCT/US2006/036721 US2006036721W WO2007038160A3 WO 2007038160 A3 WO2007038160 A3 WO 2007038160A3 US 2006036721 W US2006036721 W US 2006036721W WO 2007038160 A3 WO2007038160 A3 WO 2007038160A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
therapy
feedback
pulsed cavitational
maintenance
Prior art date
Application number
PCT/US2006/036721
Other languages
French (fr)
Other versions
WO2007038160A2 (en
Inventor
Charles A Cain
J Brian Fowlkes
Zhen Xu
Timothy L Hall
Original Assignee
Univ Michigan
Charles A Cain
J Brian Fowlkes
Zhen Xu
Timothy L Hall
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan, Charles A Cain, J Brian Fowlkes, Zhen Xu, Timothy L Hall filed Critical Univ Michigan
Priority to EP06815051A priority Critical patent/EP1926436A2/en
Priority to JP2008532360A priority patent/JP2009508649A/en
Priority to CA002623486A priority patent/CA2623486A1/en
Publication of WO2007038160A2 publication Critical patent/WO2007038160A2/en
Publication of WO2007038160A3 publication Critical patent/WO2007038160A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22088—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance ultrasound absorbing, drug activated by ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22089—Gas-bubbles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/485—Diagnostic techniques involving measuring strain or elastic properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Mechanical Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Surgical Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

Therapy methods using pulsed cavitational ultrasound therapy can include the subprocesses of initiation, maintenance, therapy, and feedback of the histotripsy process, which involves the creation and maintenance of ensembles of microbubbles and the use of feedback in order to optimize the process based on observed spatial- temporal bubble cloud dynamics. The methods provide for the subdivision or erosion of tissue, liquification of tissue, and the enhanced delivery of therapeutic agents. Various feedback mechanisms allow variation of ultrasound parameters and provide control over the pulsed cavitational process, permitting the process to be tuned for a number of applications. Such applications can include specific tissue erosion, bulk tissue homogenization, and delivery of therapeutic agents across barriers.
PCT/US2006/036721 2005-09-22 2006-09-20 Pulsed cavitational ultrasound therapy WO2007038160A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06815051A EP1926436A2 (en) 2005-09-22 2006-09-20 Pulsed cavitational ultrasound therapy
JP2008532360A JP2009508649A (en) 2005-09-22 2006-09-20 Pulsed cavitation ultrasound therapy
CA002623486A CA2623486A1 (en) 2005-09-22 2006-09-20 Pulsed cavitational ultrasound therapy

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US71970305P 2005-09-22 2005-09-22
US60/719,703 2005-09-22
US75337605P 2005-12-22 2005-12-22
US60/753,376 2005-12-22
US78632206P 2006-03-27 2006-03-27
US60/786,322 2006-03-27
US11/523,201 US20070083120A1 (en) 2005-09-22 2006-09-19 Pulsed cavitational ultrasound therapy
US11/523,201 2006-09-19

Publications (2)

Publication Number Publication Date
WO2007038160A2 WO2007038160A2 (en) 2007-04-05
WO2007038160A3 true WO2007038160A3 (en) 2009-04-16

Family

ID=37900272

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/036721 WO2007038160A2 (en) 2005-09-22 2006-09-20 Pulsed cavitational ultrasound therapy

Country Status (5)

Country Link
US (2) US20070083120A1 (en)
EP (1) EP1926436A2 (en)
JP (1) JP2009508649A (en)
CA (1) CA2623486A1 (en)
WO (1) WO2007038160A2 (en)

Families Citing this family (176)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2063529A1 (en) * 1991-03-22 1992-09-23 Katsuro Tachibana Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same
US6050943A (en) 1997-10-14 2000-04-18 Guided Therapy Systems, Inc. Imaging, therapy, and temperature monitoring ultrasonic system
US7914453B2 (en) 2000-12-28 2011-03-29 Ardent Sound, Inc. Visual imaging system for ultrasonic probe
AU2002359576A1 (en) 2001-12-03 2003-06-17 Ekos Corporation Catheter with multiple ultrasound radiating members
US7341569B2 (en) * 2004-01-30 2008-03-11 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
US7393325B2 (en) 2004-09-16 2008-07-01 Guided Therapy Systems, L.L.C. Method and system for ultrasound treatment with a multi-directional transducer
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
US20130046209A1 (en) 2011-07-10 2013-02-21 Guided Therapy Systems, Llc Systems and methods for improving an outside appearance of skin using ultrasound as an energy source
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US10864385B2 (en) 2004-09-24 2020-12-15 Guided Therapy Systems, Llc Rejuvenating skin by heating tissue for cosmetic treatment of the face and body
US11235179B2 (en) 2004-10-06 2022-02-01 Guided Therapy Systems, Llc Energy based skin gland treatment
KR101328103B1 (en) 2004-10-06 2013-11-13 가이디드 테라피 시스템스, 엘.엘.씨. Method and system for noninvasive cosmetic enhancement
US11883688B2 (en) 2004-10-06 2024-01-30 Guided Therapy Systems, Llc Energy based fat reduction
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
EP2409730A1 (en) 2004-10-06 2012-01-25 Guided Therapy Systems, L.L.C. Method and system for ultrasound tissue treatment
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US8690778B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Energy-based tissue tightening
US20060111744A1 (en) 2004-10-13 2006-05-25 Guided Therapy Systems, L.L.C. Method and system for treatment of sweat glands
US11724133B2 (en) 2004-10-07 2023-08-15 Guided Therapy Systems, Llc Ultrasound probe for treatment of skin
US11207548B2 (en) 2004-10-07 2021-12-28 Guided Therapy Systems, L.L.C. Ultrasound probe for treating skin laxity
WO2006096755A2 (en) * 2005-03-07 2006-09-14 The Brigham And Women's Hospital, Inc. Adaptive ultrasound delivery system
EP1874197A4 (en) * 2005-04-12 2010-02-10 Ekos Corp Ultrasound catheter with cavitation promoting surface
JP4695188B2 (en) 2005-04-25 2011-06-08 アーデント サウンド， インコーポレイテッド Method and apparatus for improving the safety of computer peripherals
CN101291705A (en) * 2005-06-07 2008-10-22 皇家飞利浦电子股份有限公司 Method and apparatus for ultrasound drug delivery and thermal therapy with phase-convertible fluids
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US8057408B2 (en) * 2005-09-22 2011-11-15 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
US20070083120A1 (en) * 2005-09-22 2007-04-12 Cain Charles A Pulsed cavitational ultrasound therapy
US20090048514A1 (en) * 2006-03-09 2009-02-19 Slender Medical Ltd. Device for ultrasound monitored tissue treatment
US9107798B2 (en) * 2006-03-09 2015-08-18 Slender Medical Ltd. Method and system for lipolysis and body contouring
EP2015698B1 (en) 2006-04-20 2017-11-15 Sonendo, Inc. Apparatus for treating root canals of teeth
US10835355B2 (en) 2006-04-20 2020-11-17 Sonendo, Inc. Apparatus and methods for treating root canals of teeth
EP2015846A2 (en) 2006-04-24 2009-01-21 Ekos Corporation Ultrasound therapy system
JP5450065B2 (en) * 2006-08-11 2014-03-26 コーニンクレッカ フィリップス エヌ ヴェ Ultrasound system for cerebral blood flow imaging and clot lysis using microbubbles
US7980854B2 (en) 2006-08-24 2011-07-19 Medical Dental Advanced Technologies Group, L.L.C. Dental and medical treatments and procedures
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
WO2008042855A2 (en) * 2006-09-29 2008-04-10 The Trustees Of The University Of Pennsylvania Use of ultrasound as an antivascular agent
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
WO2008092125A2 (en) * 2007-01-25 2008-07-31 Dentatek Corporation Apparatus and methods for monitoring a tooth
US20110021924A1 (en) * 2007-02-09 2011-01-27 Shriram Sethuraman Intravascular photoacoustic and utrasound echo imaging
US20150174388A1 (en) 2007-05-07 2015-06-25 Guided Therapy Systems, Llc Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
JP2010526589A (en) 2007-05-07 2010-08-05 ガイデッド セラピー システムズ， エル．エル．シー． Method and system for modulating a mediant using acoustic energy
EP2494932B1 (en) 2007-06-22 2020-05-20 Ekos Corporation Apparatus for treatment of intracranial hemorrhages
WO2009045095A1 (en) * 2007-10-02 2009-04-09 Axxion Technology B.V. Composite panel and its production
US20100274161A1 (en) * 2007-10-15 2010-10-28 Slender Medical, Ltd. Implosion techniques for ultrasound
US20100092424A1 (en) * 2007-11-21 2010-04-15 Sanghvi Narendra T Method of diagnosis and treatment of tumors using high intensity focused ultrasound
WO2009094554A2 (en) * 2008-01-25 2009-07-30 The Regents Of The University Of Michigan Histotripsy for thrombolysis
US8403850B2 (en) * 2008-03-25 2013-03-26 Wisconsin Alumni Research Foundation Rapid two/three-dimensional sector strain imaging
EP2276414A4 (en) * 2008-05-09 2012-07-04 Sonendo Inc Apparatus and methods for root canal treatments
US20090287083A1 (en) * 2008-05-14 2009-11-19 Leonid Kushculey Cavitation detector
US20090287205A1 (en) * 2008-05-16 2009-11-19 Boston Scientific Scimed, Inc. Systems and methods for preventing tissue popping caused by bubble expansion during tissue ablation
CN104987416A (en) 2008-05-23 2015-10-21 Siwa有限公司 Methods, compositions and apparatus for facilitating regeneration
CN104545998B (en) 2008-06-06 2020-07-14 奥赛拉公司 System and method for cosmetic treatment and imaging
DE102008030213A1 (en) * 2008-06-25 2009-12-31 Theuer, Axel E., Prof. Dr.-Ing. habil. Device for destruction of tumor cells and tumor tissue
US9248318B2 (en) * 2008-08-06 2016-02-02 Mirabilis Medica Inc. Optimization and feedback control of HIFU power deposition through the analysis of detected signal characteristics
FR2935097A1 (en) * 2008-08-22 2010-02-26 Theraclion THERAPEUTIC TREATMENT DEVICE
US20110178541A1 (en) * 2008-09-12 2011-07-21 Slender Medical, Ltd. Virtual ultrasonic scissors
CA2741723A1 (en) * 2008-10-24 2010-04-29 Barry Friemel Method and apparatus for feedback control of hifu treatments
GB0820377D0 (en) 2008-11-07 2008-12-17 Isis Innovation Mapping and characterization of cavitation activity
EP2378976A1 (en) * 2008-12-22 2011-10-26 Koninklijke Philips Electronics N.V. Ablation control device for real-time monitoring of tissue displacement in reaction to a force applied
JP2012513837A (en) 2008-12-24 2012-06-21 ガイデッド セラピー システムズ， エルエルシー Method and system for fat loss and / or cellulite treatment
US20100204617A1 (en) * 2009-02-12 2010-08-12 Shmuel Ben-Ezra Ultrasonic probe with acoustic output sensing
US8727986B2 (en) * 2009-02-27 2014-05-20 Wisconsin Alumni Research Foundation Method and apparatus for assessing risk of preterm delivery
WO2010118307A1 (en) * 2009-04-09 2010-10-14 The Trustees Of The University Of Pennsylvania Methods and systems for image-guided treatment of blood vessels
US8852104B2 (en) * 2009-04-15 2014-10-07 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for ultrasound assisted local delivery of drugs and biomarkers
WO2010127369A1 (en) * 2009-05-01 2010-11-04 Rational Biotechnology Inc. Eit (electrical impedance tomography) guided sonoporation, ultrasound tissue ablation and their use thereof
US20100286518A1 (en) * 2009-05-11 2010-11-11 General Electric Company Ultrasound system and method to deliver therapy based on user defined treatment spaces
US20100286520A1 (en) * 2009-05-11 2010-11-11 General Electric Company Ultrasound system and method to determine mechanical properties of a target region
US20100286519A1 (en) * 2009-05-11 2010-11-11 General Electric Company Ultrasound system and method to automatically identify and treat adipose tissue
JP5850837B2 (en) 2009-08-17 2016-02-03 ヒストソニックス，インコーポレーテッド Disposable acoustic coupling media container
EP2470267B1 (en) * 2009-08-26 2015-11-11 The Regents Of The University Of Michigan Micromanipulator control arm for therapeutic and imaging ultrasound transducers
US9901753B2 (en) * 2009-08-26 2018-02-27 The Regents Of The University Of Michigan Ultrasound lithotripsy and histotripsy for using controlled bubble cloud cavitation in fractionating urinary stones
GB0916635D0 (en) * 2009-09-22 2009-11-04 Isis Innovation Ultrasound systems
US8539813B2 (en) 2009-09-22 2013-09-24 The Regents Of The University Of Michigan Gel phantoms for testing cavitational ultrasound (histotripsy) transducers
GB0916634D0 (en) 2009-09-22 2009-11-04 Isis Innovation Ultrasound systems
EP2312303A1 (en) * 2009-10-12 2011-04-20 Koninklijke Philips Electronics N.V. Magnetic resonance imaging system and method for detecting a gas bubble
CA2780800C (en) 2009-11-13 2023-09-12 Sonendo, Inc. Liquid jet apparatus and methods for dental treatments
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
JP5735488B2 (en) * 2010-04-09 2015-06-17 株式会社日立製作所 Ultrasound diagnostic treatment device
US8876740B2 (en) 2010-04-12 2014-11-04 University Of Washington Methods and systems for non-invasive treatment of tissue using high intensity focused ultrasound therapy
WO2011133922A2 (en) * 2010-04-22 2011-10-27 The University Of Washington Through Its Center For Commercialization Ultrasound based method and apparatus for stone detection and to facilitate clearance thereof
US8954564B2 (en) * 2010-05-28 2015-02-10 Red Hat, Inc. Cross-cloud vendor mapping service in cloud marketplace
US10466096B2 (en) 2010-06-01 2019-11-05 Drexel University Fiber optic hydrophone sensors and uses thereof
US8661908B2 (en) * 2010-06-01 2014-03-04 Drexel University Fiber optic hydrophone sensors and uses thereof
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
EP2600937B8 (en) 2010-08-02 2024-03-06 Guided Therapy Systems, L.L.C. Systems for treating acute and/or chronic injuries in soft tissue
EP3511017A1 (en) 2010-09-27 2019-07-17 Siwa Corporation Selective removal of age-modified cells for treatment of atherosclerosis
AU2011316839B2 (en) 2010-10-21 2015-04-23 Sonendo, Inc. Apparatus, methods, and compositions for endodontic treatments
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
US8721571B2 (en) 2010-11-22 2014-05-13 Siwa Corporation Selective removal of cells having accumulated agents
EP2651305B1 (en) * 2010-12-14 2016-03-16 Koninklijke Philips N.V. Ultrasound imaging system and method with peak intensity detection
US20140303453A1 (en) * 2011-07-06 2014-10-09 Ontario Hospital Research Institute System and Method for Generating Composite Measures of Variability
WO2013012641A1 (en) 2011-07-11 2013-01-24 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
US11865371B2 (en) 2011-07-15 2024-01-09 The Board of Regents of the University of Texas Syster Apparatus for generating therapeutic shockwaves and applications of same
RU2472545C1 (en) * 2011-07-28 2013-01-20 Вера Александровна Хохлова Method for non-invasive destruction of biological tissues lying behind thoracic bones
US9144694B2 (en) 2011-08-10 2015-09-29 The Regents Of The University Of Michigan Lesion generation through bone using histotripsy therapy without aberration correction
WO2013055795A1 (en) * 2011-10-10 2013-04-18 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy with shear wave elastography feedback
WO2013098732A1 (en) * 2011-12-29 2013-07-04 Koninklijke Philips Electronics N.V. Apparatus and method for ultrasound monitoring of ablation by a combination of the breaking down of air bubbles and imaging sequences
AU2013235347B2 (en) 2012-03-22 2017-11-09 Sonendo, Inc. Apparatus and methods for cleaning teeth
US10631962B2 (en) 2012-04-13 2020-04-28 Sonendo, Inc. Apparatus and methods for cleaning teeth and gingival pockets
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
US9049783B2 (en) 2012-04-13 2015-06-02 Histosonics, Inc. Systems and methods for obtaining large creepage isolation on printed circuit boards
EP2844343B1 (en) 2012-04-30 2018-11-21 The Regents Of The University Of Michigan Ultrasound transducer manufacturing using rapid-prototyping method
CN104363959A (en) * 2012-05-11 2015-02-18 加利福尼亚大学董事会 Portable device to initiate and monitor treatment of stroke victims in the field
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
WO2014055906A1 (en) * 2012-10-05 2014-04-10 The Regents Of The University Of Michigan Bubble-induced color doppler feedback during histotripsy
US9827345B2 (en) 2012-11-08 2017-11-28 Smith & Nephew, Inc. Methods and compositions suitable for improved reattachment of detached cartilage to subchondral bone
WO2014074806A1 (en) 2012-11-08 2014-05-15 Smith & Nephew, Inc-- Improved reattachment of detached cartilage to subchondral bone
WO2014100751A1 (en) 2012-12-20 2014-06-26 Sonendo, Inc. Apparatus and methods for cleaning teeth and root canals
US10363120B2 (en) 2012-12-20 2019-07-30 Sonendo, Inc. Apparatus and methods for cleaning teeth and root canals
CA2900252C (en) 2013-02-04 2021-11-16 Sonendo, Inc. Dental treatment system
KR101462023B1 (en) * 2013-02-28 2014-11-18 알피니언메디칼시스템 주식회사 Method for Detecting Cavitation and Ultrasound Medical Apparatus Therefor
CN204017181U (en) 2013-03-08 2014-12-17 奥赛拉公司 Aesthstic imaging and processing system, multifocal processing system and perform the system of aesthetic procedure
US10561862B2 (en) 2013-03-15 2020-02-18 Guided Therapy Systems, Llc Ultrasound treatment device and methods of use
WO2014179619A2 (en) 2013-05-01 2014-11-06 Sonendo, Inc. Apparatus and methods for treating teeth
EP3013277B1 (en) 2013-06-26 2023-07-19 Sonendo, Inc. Apparatus and methods for filling teeth and root canals
EP3013421B8 (en) * 2013-06-28 2020-04-08 Koninklijke Philips N.V. Transducer placement and registration for image-guided sonothrombolysis
US11432900B2 (en) 2013-07-03 2022-09-06 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
EP4166194A1 (en) * 2013-07-03 2023-04-19 Histosonics, Inc. Histotripsy excitation sequences optimized for bubble cloud formation using shock scattering
WO2015027164A1 (en) 2013-08-22 2015-02-26 The Regents Of The University Of Michigan Histotripsy using very short ultrasound pulses
US9763688B2 (en) 2013-11-20 2017-09-19 Ethicon Llc Ultrasonic surgical instrument with features for forming bubbles to enhance cavitation
US9468932B2 (en) * 2013-12-13 2016-10-18 Elwha Llc Acoustic source fragmentation system for breaking ground material
WO2015147357A1 (en) * 2014-03-27 2015-10-01 알피니언메디칼시스템 주식회사 Ultrasound monitoring device for detecting cavitation and method therefor
SG11201608691YA (en) 2014-04-18 2016-11-29 Ulthera Inc Band transducer ultrasound therapy
US20150320384A1 (en) * 2014-05-06 2015-11-12 University Of Washington Methods and Systems for Detecting an Object in a Subject with Ultrasound
WO2016038696A1 (en) * 2014-09-10 2016-03-17 株式会社日立製作所 Ultrasound irradiation device
JP6976847B2 (en) 2014-09-19 2021-12-08 シワ コーポレイション Anti-AGE antibody for treating inflammation and autoimmune disorders
US10358502B2 (en) 2014-12-18 2019-07-23 Siwa Corporation Product and method for treating sarcopenia
US9993535B2 (en) 2014-12-18 2018-06-12 Siwa Corporation Method and composition for treating sarcopenia
WO2016144931A1 (en) 2015-03-09 2016-09-15 The Research Foundation For The State University Of New York Systems and methods for promoting cellular activities for tissue maintenance, repair, and regeneration
JP6391805B2 (en) * 2015-03-16 2018-09-19 株式会社日立製作所 Chemical solution administration device and method of operating the same
CN107533134B (en) * 2015-04-15 2021-04-27 音频像素有限公司 Camera, audio sound system, method and system for detecting position of object
EP3307388B1 (en) 2015-06-10 2022-06-22 Ekos Corporation Ultrasound catheter
WO2016210133A1 (en) * 2015-06-24 2016-12-29 The Regents Of The Universtiy Of Michigan Histotripsy therapy systems and methods for the treatment of brain tissue
US11609427B2 (en) 2015-10-16 2023-03-21 Ostendo Technologies, Inc. Dual-mode augmented/virtual reality (AR/VR) near-eye wearable displays
US10507035B2 (en) 2015-10-20 2019-12-17 Ethicon Llc Surgical instrument providing ultrasonic tissue emulsification and ultrasonic shearing
US11106273B2 (en) * 2015-10-30 2021-08-31 Ostendo Technologies, Inc. System and methods for on-body gestural interfaces and projection displays
US10345594B2 (en) 2015-12-18 2019-07-09 Ostendo Technologies, Inc. Systems and methods for augmented near-eye wearable displays
US10578882B2 (en) 2015-12-28 2020-03-03 Ostendo Technologies, Inc. Non-telecentric emissive micro-pixel array light modulators and methods of fabrication thereof
ES2939604T3 (en) 2016-01-18 2023-04-25 Ulthera Inc Compact ultrasonic device having an annular ultrasonic array peripherally electrically connected to a flexible printed circuit board
HUE058854T2 (en) 2016-02-19 2022-09-28 Siwa Corp Method and composition for treating cancer, killing metastatic cancer cells and preventing cancer metastasis using antibody to advanced glycation end products (age)
WO2017173414A1 (en) * 2016-04-01 2017-10-05 Fujifilm Sonosite, Inc. Dual frequency ultrasound transducer including an ultrahigh frequency transducer stack and a low frequency ultrasound transducer stack
US10806544B2 (en) 2016-04-04 2020-10-20 Sonendo, Inc. Systems and methods for removing foreign objects from root canals
US10353203B2 (en) 2016-04-05 2019-07-16 Ostendo Technologies, Inc. Augmented/virtual reality near-eye displays with edge imaging lens comprising a plurality of display devices
CA3057829A1 (en) 2016-04-15 2017-10-19 Siwa Corporation Anti-age antibodies for treating neurodegenerative disorders
US10453431B2 (en) 2016-04-28 2019-10-22 Ostendo Technologies, Inc. Integrated near-far light field display systems
US10522106B2 (en) 2016-05-05 2019-12-31 Ostendo Technologies, Inc. Methods and apparatus for active transparency modulation
WO2017222535A1 (en) 2016-06-23 2017-12-28 Siwa Corporation Vaccines for use in treating various diseases and disorders
US11241218B2 (en) 2016-08-16 2022-02-08 Ulthera, Inc. Systems and methods for cosmetic ultrasound treatment of skin
CN106730424B (en) * 2016-12-19 2018-10-30 西安交通大学 Hundred microsecond pulse ultrasonic tissue of confocal harmonic superposition damages mode control method
US10961321B1 (en) 2017-01-06 2021-03-30 Siwa Corporation Methods and compositions for treating pain associated with inflammation
US10858449B1 (en) 2017-01-06 2020-12-08 Siwa Corporation Methods and compositions for treating osteoarthritis
US10995151B1 (en) 2017-01-06 2021-05-04 Siwa Corporation Methods and compositions for treating disease-related cachexia
US10925937B1 (en) 2017-01-06 2021-02-23 Siwa Corporation Vaccines for use in treating juvenile disorders associated with inflammation
US11259778B2 (en) 2017-03-22 2022-03-01 Boston Scientific Scimed Inc. All optical atrial ablation device
EP3609923A1 (en) 2017-04-13 2020-02-19 Siwa Corporation Humanized monoclonal advanced glycation end-product antibody
JP7111744B2 (en) * 2017-05-23 2022-08-02 インサイテック・リミテッド Systems and methods for selective targeted opening of the blood-brain barrier
US20190009110A1 (en) * 2017-07-06 2019-01-10 Slender Medical Ltd. Ultrasound energy applicator
US10478211B2 (en) 2017-07-07 2019-11-19 Ethicon Llc Features to promote removal of debris from within ultrasonic surgical instrument
CA3073552A1 (en) 2017-09-01 2019-03-07 Dalhousie University Transducer assembly for generating focused ultrasound
US11518801B1 (en) 2017-12-22 2022-12-06 Siwa Corporation Methods and compositions for treating diabetes and diabetic complications
US11944849B2 (en) 2018-02-20 2024-04-02 Ulthera, Inc. Systems and methods for combined cosmetic treatment of cellulite with ultrasound
FR3087642B1 (en) * 2018-10-24 2020-11-06 Commissariat Energie Atomique METHOD AND SYSTEM FOR SPECTRAL ANALYSIS AND DETERMINATION OF A MARKER ENABLING THE SAFETY OF THERAPEUTIC ULTRASONIC INTERVENTIONS
EP3886737A4 (en) * 2018-11-28 2022-08-24 Histosonics, Inc. Histotripsy systems and methods
KR102273928B1 (en) * 2019-05-15 2021-07-14 연세대학교 산학협력단 Light radiation device that secures light transmission depth by focused ultrasonic wave guidance and method of controlling light output by feedback control of ultrasonic wave
CN114126709A (en) * 2019-07-16 2022-03-01 阿普劳德医疗公司 System and method for biomineralization using microbubbles
JP2022542848A (en) * 2019-07-24 2022-10-07 エグザクト イメージング インコーポレイテッド Systems and methods for ultrasound perfusion imaging
CN110575201B (en) * 2019-10-09 2021-12-24 珠海医凯电子科技有限公司 Ultrasonic microbubble cavitation imaging method and device based on reverse Golay code
KR102320038B1 (en) * 2019-12-06 2021-11-01 한국과학기술연구원 Apparatus and method for precise mechanical tissue ablation using pressure modulated focused ultrasound
AU2021213168A1 (en) 2020-01-28 2022-09-01 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
USD997355S1 (en) 2020-10-07 2023-08-29 Sonendo, Inc. Dental treatment instrument
DE102022200740B3 (en) * 2022-01-24 2023-01-26 Siemens Healthcare Gmbh Therapy device for ultrasound treatment
CN116421305B (en) * 2023-06-08 2023-09-15 上海瑞柯恩激光技术有限公司 Laser surgery control system, coupling system and laser surgery equipment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6719449B1 (en) * 1998-10-28 2004-04-13 Covaris, Inc. Apparatus and method for controlling sonic treatment

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4269174A (en) * 1979-08-06 1981-05-26 Medical Dynamics, Inc. Transcutaneous vasectomy apparatus and method
US5143073A (en) * 1983-12-14 1992-09-01 Edap International, S.A. Wave apparatus system
USRE33590E (en) * 1983-12-14 1991-05-21 Edap International, S.A. Method for examining, localizing and treating with ultrasound
DE3425705A1 (en) * 1984-07-12 1986-01-16 Siemens AG, 1000 Berlin und 8000 München PHASED ARRAY DEVICE
US5431621A (en) * 1984-11-26 1995-07-11 Edap International Process and device of an anatomic anomaly by means of elastic waves, with tracking of the target and automatic triggering of the shootings
US4689986A (en) * 1985-03-13 1987-09-01 The University Of Michigan Variable frequency gas-bubble-manipulating apparatus and method
JPS61209643A (en) * 1985-03-15 1986-09-17 株式会社東芝 Ultrasonic diagnostic and medical treatment apparatus
DE3607949A1 (en) * 1986-03-11 1987-09-17 Wolf Gmbh Richard METHOD FOR DETECTING POSSIBLE TISSUE DAMAGE IN THE MEDICAL APPLICATION OF HIGH-ENERGY SOUND
FR2614747B1 (en) * 1987-04-28 1989-07-28 Dory Jacques ELASTIC PULSE GENERATOR HAVING A PREDETERMINED WAVEFORM AND ITS APPLICATION TO TREATMENT OR MEDICAL DIAGNOSIS
FR2614722B1 (en) * 1987-04-28 1992-04-17 Dory Jacques ACOUSTIC FILTER FOR SUPPRESSING OR MITIGATING NEGATIVE ALTERNATIONS OF AN ELASTIC WAVE AND ELASTIC WAVE GENERATOR COMPRISING SUCH A FILTER
FR2619448B1 (en) * 1987-08-14 1990-01-19 Edap Int METHOD AND DEVICE FOR TISSUE CHARACTERIZATION BY REFLECTION OF ULTRASONIC PULSES WITH BROADBAND FREQUENCIES, TRANSPOSITION OF THE ECHO FREQUENCY SPECTRUM IN AN AUDIBLE RANGE AND LISTENING DIAGNOSIS
DE3741201A1 (en) * 1987-12-02 1989-06-15 Schering Ag ULTRASONIC PROCESS AND METHOD FOR IMPLEMENTING IT
US5163421A (en) * 1988-01-22 1992-11-17 Angiosonics, Inc. In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging
US5209221A (en) * 1988-03-01 1993-05-11 Richard Wolf Gmbh Ultrasonic treatment of pathological tissue
US4938217A (en) * 1988-06-21 1990-07-03 Massachusetts Institute Of Technology Electronically-controlled variable focus ultrasound hyperthermia system
FR2642640B1 (en) * 1989-02-08 1991-05-10 Centre Nat Rech Scient METHOD AND DEVICE FOR FOCUSING ULTRASOUND IN TISSUES
JPH02217000A (en) * 1989-02-16 1990-08-29 Hitachi Ltd Ultrasonic wave probe
FR2643252B1 (en) * 1989-02-21 1991-06-07 Technomed Int Sa APPARATUS FOR THE SELECTIVE DESTRUCTION OF CELLS INCLUDING SOFT TISSUES AND BONES WITHIN THE BODY OF A LIVING BODY BY IMPLOSION OF GAS BUBBLES
US5435311A (en) * 1989-06-27 1995-07-25 Hitachi, Ltd. Ultrasound therapeutic system
US5065761A (en) * 1989-07-12 1991-11-19 Diasonics, Inc. Lithotripsy system
US6088613A (en) * 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5091893A (en) * 1990-04-05 1992-02-25 General Electric Company Ultrasonic array with a high density of electrical connections
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
US6344489B1 (en) * 1991-02-14 2002-02-05 Wayne State University Stabilized gas-enriched and gas-supersaturated liquids
US5316000A (en) * 1991-03-05 1994-05-31 Technomed International (Societe Anonyme) Use of at least one composite piezoelectric transducer in the manufacture of an ultrasonic therapy apparatus for applying therapy, in a body zone, in particular to concretions, to tissue, or to bones, of a living being and method of ultrasonic therapy
US5524620A (en) * 1991-11-12 1996-06-11 November Technologies Ltd. Ablation of blood thrombi by means of acoustic energy
ATE144124T1 (en) * 1991-12-20 1996-11-15 Technomed Medical Systems DEVICE FOR ULTRASONIC THERAPY EMITTING SOUND WAVES, THERMAL EFFECTS AND CAVITATION EFFECTS
US6436078B1 (en) * 1994-12-06 2002-08-20 Pal Svedman Transdermal perfusion of fluids
DE4207463C2 (en) * 1992-03-10 1996-03-28 Siemens Ag Arrangement for the therapy of tissue with ultrasound
WO1993019705A1 (en) * 1992-03-31 1993-10-14 Massachusetts Institute Of Technology Apparatus and method for acoustic heat generation and hyperthermia
US5230340A (en) * 1992-04-13 1993-07-27 General Electric Company Ultrasound imaging system with improved dynamic focusing
US5295484A (en) * 1992-05-19 1994-03-22 Arizona Board Of Regents For And On Behalf Of The University Of Arizona Apparatus and method for intra-cardiac ablation of arrhythmias
WO1994006380A1 (en) * 1992-09-16 1994-03-31 Hitachi, Ltd. Ultrasonic irradiation apparatus and processor using the same
US5573497A (en) * 1994-11-30 1996-11-12 Technomed Medical Systems And Institut National High-intensity ultrasound therapy method and apparatus with controlled cavitation effect and reduced side lobes
US5469852A (en) * 1993-03-12 1995-11-28 Kabushiki Kaisha Toshiba Ultrasound diagnosis apparatus and probe therefor
US6251100B1 (en) * 1993-09-24 2001-06-26 Transmedica International, Inc. Laser assisted topical anesthetic permeation
US5509896A (en) * 1994-09-09 1996-04-23 Coraje, Inc. Enhancement of thrombolysis with external ultrasound
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
US5520188A (en) * 1994-11-02 1996-05-28 Focus Surgery Inc. Annular array transducer
US5678554A (en) * 1996-07-02 1997-10-21 Acuson Corporation Ultrasound transducer for multiple focusing and method for manufacture thereof
US6176842B1 (en) * 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
US5873902A (en) * 1995-03-31 1999-02-23 Focus Surgery, Inc. Ultrasound intensity determining method and apparatus
US5617862A (en) * 1995-05-02 1997-04-08 Acuson Corporation Method and apparatus for beamformer system with variable aperture
US6521211B1 (en) * 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US5648098A (en) * 1995-10-17 1997-07-15 The Board Of Regents Of The University Of Nebraska Thrombolytic agents and methods of treatment for thrombosis
US5590657A (en) * 1995-11-06 1997-01-07 The Regents Of The University Of Michigan Phased array ultrasound system and method for cardiac ablation
CH691345A5 (en) * 1996-04-18 2001-07-13 Siemens Ag Therapy device by a simple adjustment of a desired distance from a reference point.
US20020045890A1 (en) * 1996-04-24 2002-04-18 The Regents Of The University O F California Opto-acoustic thrombolysis
US6022309A (en) * 1996-04-24 2000-02-08 The Regents Of The University Of California Opto-acoustic thrombolysis
US5724972A (en) * 1996-05-02 1998-03-10 Acuson Corporation Method and apparatus for distributed focus control with slope tracking
US5717657A (en) * 1996-06-24 1998-02-10 The United States Of America As Represented By The Secretary Of The Navy Acoustical cavitation suppressor for flow fields
US5753929A (en) * 1996-08-28 1998-05-19 Motorola, Inc. Multi-directional optocoupler and method of manufacture
DE19635593C1 (en) * 1996-09-02 1998-04-23 Siemens Ag Ultrasound transducer for diagnostic and therapeutic use
CA2213948C (en) * 1996-09-19 2006-06-06 United States Surgical Corporation Ultrasonic dissector
US6036667A (en) * 1996-10-04 2000-03-14 United States Surgical Corporation Ultrasonic dissection and coagulation system
US5769790A (en) * 1996-10-25 1998-06-23 General Electric Company Focused ultrasound surgery system guided by ultrasound imaging
US5827204A (en) * 1996-11-26 1998-10-27 Grandia; Willem Medical noninvasive operations using focused modulated high power ultrasound
US6001069A (en) * 1997-05-01 1999-12-14 Ekos Corporation Ultrasound catheter for providing a therapeutic effect to a vessel of a body
US5879314A (en) * 1997-06-30 1999-03-09 Cybersonics, Inc. Transducer assembly and method for coupling ultrasonic energy to a body for thrombolysis of vascular thrombi
US6093883A (en) * 1997-07-15 2000-07-25 Focus Surgery, Inc. Ultrasound intensity determining method and apparatus
US6128958A (en) * 1997-09-11 2000-10-10 The Regents Of The University Of Michigan Phased array system architecture
US6113558A (en) * 1997-09-29 2000-09-05 Angiosonics Inc. Pulsed mode lysis method
US6511444B2 (en) * 1998-02-17 2003-01-28 Brigham And Women's Hospital Transmyocardial revascularization using ultrasound
US6659105B2 (en) * 1998-02-26 2003-12-09 Senorx, Inc. Tissue specimen isolating and damaging device and method
US6685640B1 (en) * 1998-03-30 2004-02-03 Focus Surgery, Inc. Ablation system
FR2778573B1 (en) * 1998-05-13 2000-09-22 Technomed Medical Systems FREQUENCY ADJUSTMENT IN A HIGH INTENSITY FOCUSED ULTRASOUND TREATMENT APPARATUS
JP4095729B2 (en) * 1998-10-26 2008-06-04 株式会社日立製作所 Therapeutic ultrasound system
US7687039B2 (en) * 1998-10-28 2010-03-30 Covaris, Inc. Methods and systems for modulating acoustic energy delivery
AU1128600A (en) * 1998-11-20 2000-06-13 Joie P. Jones Methods for selectively dissolving and removing materials using ultra-high frequency ultrasound
US6309355B1 (en) * 1998-12-22 2001-10-30 The Regents Of The University Of Michigan Method and assembly for performing ultrasound surgery using cavitation
US6508774B1 (en) * 1999-03-09 2003-01-21 Transurgical, Inc. Hifu applications with feedback control
US6890332B2 (en) * 1999-05-24 2005-05-10 Csaba Truckai Electrical discharge devices and techniques for medical procedures
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
US6524251B2 (en) * 1999-10-05 2003-02-25 Omnisonics Medical Technologies, Inc. Ultrasonic device for tissue ablation and sheath for use therewith
US6391020B1 (en) * 1999-10-06 2002-05-21 The Regents Of The Univerity Of Michigan Photodisruptive laser nucleation and ultrasonically-driven cavitation of tissues and materials
EP1229839A4 (en) * 1999-10-25 2005-12-07 Therus Corp Use of focused ultrasound for vascular sealing
US7300414B1 (en) * 1999-11-01 2007-11-27 University Of Cincinnati Transcranial ultrasound thrombolysis system and method of treating a stroke
CA2394892A1 (en) * 1999-12-23 2001-06-28 Therus Corporation Ultrasound transducers for imaging and therapy
US6635017B1 (en) * 2000-02-09 2003-10-21 Spentech, Inc. Method and apparatus combining diagnostic ultrasound with therapeutic ultrasound to enhance thrombolysis
US6750463B1 (en) * 2000-02-29 2004-06-15 Hill-Rom Services, Inc. Optical isolation apparatus and method
US6490469B2 (en) * 2000-03-15 2002-12-03 The Regents Of The University Of California Method and apparatus for dynamic focusing of ultrasound energy
US6419648B1 (en) * 2000-04-21 2002-07-16 Insightec-Txsonics Ltd. Systems and methods for reducing secondary hot spots in a phased array focused ultrasound system
US6543272B1 (en) * 2000-04-21 2003-04-08 Insightec-Txsonics Ltd. Systems and methods for testing and calibrating a focused ultrasound transducer array
AU6321301A (en) * 2000-05-16 2001-11-26 Atrionix Inc Apparatus and method incorporating an ultrasound transducer onto a delivery member
US6556750B2 (en) * 2000-05-26 2003-04-29 Fairchild Semiconductor Corporation Bi-directional optical coupler
US6506171B1 (en) * 2000-07-27 2003-01-14 Insightec-Txsonics, Ltd System and methods for controlling distribution of acoustic energy around a focal point using a focused ultrasound system
US6506154B1 (en) * 2000-11-28 2003-01-14 Insightec-Txsonics, Ltd. Systems and methods for controlling a phased array focused ultrasound system
US6645162B2 (en) * 2000-12-27 2003-11-11 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
US6626854B2 (en) * 2000-12-27 2003-09-30 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
US7347855B2 (en) * 2001-10-29 2008-03-25 Ultrashape Ltd. Non-invasive ultrasonic body contouring
US20020099356A1 (en) * 2001-01-19 2002-07-25 Unger Evan C. Transmembrane transport apparatus and method
US6559644B2 (en) * 2001-05-30 2003-05-06 Insightec - Txsonics Ltd. MRI-based temperature mapping with error compensation
US6735461B2 (en) * 2001-06-19 2004-05-11 Insightec-Txsonics Ltd Focused ultrasound system with MRI synchronization
US7175596B2 (en) * 2001-10-29 2007-02-13 Insightec-Txsonics Ltd System and method for sensing and locating disturbances in an energy path of a focused ultrasound system
US20040243021A1 (en) * 2001-11-06 2004-12-02 Murphy John C. Device for thermal stimulation of small neural fibers
US6522142B1 (en) * 2001-12-14 2003-02-18 Insightec-Txsonics Ltd. MRI-guided temperature mapping of tissue undergoing thermal treatment
SG114521A1 (en) * 2002-01-21 2005-09-28 Univ Nanyang Ultrasonic treatment of breast cancers
US6736814B2 (en) * 2002-02-28 2004-05-18 Misonix, Incorporated Ultrasonic medical treatment device for bipolar RF cauterization and related method
US20030181890A1 (en) * 2002-03-22 2003-09-25 Schulze Dale R. Medical device that removably attaches to a bodily organ
BR0215785A (en) * 2002-06-25 2006-06-06 Ultrashape Inc Useful devices and methodologies for body aesthetics
US6705994B2 (en) * 2002-07-08 2004-03-16 Insightec - Image Guided Treatment Ltd Tissue inhomogeneity correction in ultrasound imaging
US6852082B2 (en) * 2002-07-17 2005-02-08 Adam Strickberger Apparatus and methods for performing non-invasive vasectomies
US7367948B2 (en) * 2002-08-29 2008-05-06 The Regents Of The University Of Michigan Acoustic monitoring method and system in laser-induced optical breakdown (LIOB)
US7004282B2 (en) * 2002-10-28 2006-02-28 Misonix, Incorporated Ultrasonic horn
US7374551B2 (en) * 2003-02-19 2008-05-20 Pittsburgh Plastic Surgery Research Associates Minimally invasive fat cavitation method
US7377900B2 (en) * 2003-06-02 2008-05-27 Insightec - Image Guided Treatment Ltd. Endo-cavity focused ultrasound transducer
US7341569B2 (en) * 2004-01-30 2008-03-11 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
JP2007520307A (en) * 2004-02-06 2007-07-26 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミティド Microbubble local formation method, cavitation effect control and heating effect control by using enhanced ultrasound
US7196313B2 (en) * 2004-04-02 2007-03-27 Fairchild Semiconductor Corporation Surface mount multi-channel optocoupler
US20060060991A1 (en) * 2004-09-21 2006-03-23 Interuniversitair Microelektronica Centrum (Imec) Method and apparatus for controlled transient cavitation
US20070016039A1 (en) * 2005-06-21 2007-01-18 Insightec-Image Guided Treatment Ltd. Controlled, non-linear focused ultrasound treatment
US20070010805A1 (en) * 2005-07-08 2007-01-11 Fedewa Russell J Method and apparatus for the treatment of tissue
US20070065420A1 (en) * 2005-08-23 2007-03-22 Johnson Lanny L Ultrasound Therapy Resulting in Bone Marrow Rejuvenation
US20070083120A1 (en) * 2005-09-22 2007-04-12 Cain Charles A Pulsed cavitational ultrasound therapy
JP5850837B2 (en) * 2009-08-17 2016-02-03 ヒストソニックス，インコーポレーテッド Disposable acoustic coupling media container

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6719449B1 (en) * 1998-10-28 2004-04-13 Covaris, Inc. Apparatus and method for controlling sonic treatment

Also Published As

Publication number Publication date
US20070083120A1 (en) 2007-04-12
US20100069797A1 (en) 2010-03-18
CA2623486A1 (en) 2007-04-05
JP2009508649A (en) 2009-03-05
EP1926436A2 (en) 2008-06-04
WO2007038160A2 (en) 2007-04-05

Similar Documents

Publication Publication Date Title
WO2007038160A3 (en) Pulsed cavitational ultrasound therapy
DE602006012847D1 (en) ULTRASONIC UNIT AND METHOD FOR MIXING FLÜ
ATE432060T1 (en) PULSE MANIPULATION FOR CONTROL OF A PHACOEMULSIFICATION SYSTEM
MX2011007840A (en) Apparatus for decontamination by atomisation.
ATE548124T1 (en) DISPENSING DEVICE
ATE500136T1 (en) MACHINE FOR FILLING CUPS WITH FOOD AND FOOD
TW200626195A (en) Surgical prep solution applicator
WO2006062939A3 (en) Bone treatment systems and methods
WO2005111238A3 (en) Aptamer-mediated intracellular delivery of therapeutic oligonucleotides
WO2011041652A3 (en) Electrochemical treatment of liquids using dose control
WO2007114934A3 (en) Method and apparatus for generating vascular treatment foam
WO2008047084A3 (en) Ballast water treatment methods and apparatus
AU2012338949A8 (en) Sonotrode and device for reducing and eliminating foaming of liquid products
WO2005118601A3 (en) Sulfonylethyl phosphorodiamidates for use in the treatment of cancer
WO2008003056A3 (en) Wastewater disinfection apparatus and methods
EP1883447A4 (en) A high velocity liquid-gas stream device for administering therapeutic substances
ATE510669T1 (en) DOSE TRANSFER DEVICE
WO2009070739A3 (en) Systems, devices, and methods for directly energizing water molecule composition
TW200739995A (en) Laser irradiation apparatus
WO2008124330A3 (en) Systems and methods for delivering a fluid drug
BRPI0410153A (en) system for producing and distributing chlorine dioxide
WO2007008794A3 (en) Devices and methods for the treatment of bone fracture
MY153932A (en) A medicinal product and treatment
WO2009071788A3 (en) Method and device for selective etching
WO2007124148A3 (en) Treatment of connective tissue disorders

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2623486

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2008532360

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006815051

Country of ref document: EP