WO2006076361A3 - Bilateral differential pulse method for measuring brain activity - Google Patents

Bilateral differential pulse method for measuring brain activity Download PDF

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Publication number
WO2006076361A3
WO2006076361A3 PCT/US2006/000817 US2006000817W WO2006076361A3 WO 2006076361 A3 WO2006076361 A3 WO 2006076361A3 US 2006000817 W US2006000817 W US 2006000817W WO 2006076361 A3 WO2006076361 A3 WO 2006076361A3
Authority
WO
WIPO (PCT)
Prior art keywords
brain
activity
subject
human subject
brain activity
Prior art date
Application number
PCT/US2006/000817
Other languages
French (fr)
Other versions
WO2006076361A2 (en
Inventor
Ii Edward C Brainard
Original Assignee
Ii Edward C Brainard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ii Edward C Brainard filed Critical Ii Edward C Brainard
Priority to US11/664,688 priority Critical patent/US7547284B2/en
Priority to CA2593538A priority patent/CA2593538C/en
Publication of WO2006076361A2 publication Critical patent/WO2006076361A2/en
Publication of WO2006076361A3 publication Critical patent/WO2006076361A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Neurosurgery (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A method of measuring human brain activity includes the steps of simultaneously measuring pulses at two locations on a human subject that each receives blood from a different carotid artery that feeds a respective one of left and right hemispheres of the brain of the human subject, determining pulse characteristics from the measured pulses, and evaluating relative left and right hemisphere activity of the brain of the human subject based on the determined pulse characteristics. The method may use dual photoplethysmograhic blood pulse sensors that measure left and right hemisphere activity by determining pulse amplitude difference and time or phase differences between the earlobes while the subject carries out various mental functions. The data from the sensors are processed to provide a measure of brain function and the mental activity of the subject.
PCT/US2006/000817 2005-01-14 2006-01-12 Bilateral differential pulse method for measuring brain activity WO2006076361A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/664,688 US7547284B2 (en) 2005-01-14 2006-01-12 Bilateral differential pulse method for measuring brain activity
CA2593538A CA2593538C (en) 2005-01-14 2006-01-12 Bilateral differential pulse method for measuring brain activity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64362705P 2005-01-14 2005-01-14
US60/643,627 2005-01-14

Publications (2)

Publication Number Publication Date
WO2006076361A2 WO2006076361A2 (en) 2006-07-20
WO2006076361A3 true WO2006076361A3 (en) 2007-01-04

Family

ID=36678135

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/000817 WO2006076361A2 (en) 2005-01-14 2006-01-12 Bilateral differential pulse method for measuring brain activity

Country Status (3)

Country Link
US (1) US7547284B2 (en)
CA (1) CA2593538C (en)
WO (1) WO2006076361A2 (en)

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US8211031B2 (en) * 2002-01-15 2012-07-03 Orsan Medical Technologies Ltd. Non-invasive intracranial monitor
WO2006011128A1 (en) * 2004-07-15 2006-02-02 Orsan Medical Technologies Ltd. Cerebral perfusion monitor
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
ES2573323T3 (en) 2006-03-29 2016-06-07 Dignity Health Electrical stimulation of cranial nerve microburst for the treatment of medical conditions
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869885B2 (en) * 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US7974701B2 (en) * 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
EP3031395A1 (en) * 2008-10-07 2016-06-15 Orsan Medical Technologies Ltd. Monitoring of acute stroke patients
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
US8460196B2 (en) * 2009-05-29 2013-06-11 Atlantis Limited Partnership Method and apparatus for monitoring brain activity
DE102009037892A1 (en) * 2009-08-18 2011-02-24 Horst Sonntag Pulse measurement device
US9068733B2 (en) * 2010-01-09 2015-06-30 David M. Medinis LED lamp with actively cooled heat sink
US9345411B2 (en) * 2011-02-09 2016-05-24 Orsan Medical Technologies, Ltd. Devices and methods for monitoring cerebral hemodynamic conditions
US8452382B1 (en) * 2012-09-21 2013-05-28 Brooklands Inc. Non-contact thermometer sensing a carotid artery
US11596320B2 (en) * 2013-08-16 2023-03-07 Texas Instruments Incorporated Blood pulse measurement based on capacitive sensing
CN104434052A (en) * 2014-11-21 2015-03-25 广西智通节能环保科技有限公司 Neck pulse monitor
CN104873184B (en) * 2015-05-08 2017-09-29 上海与德通讯技术有限公司 A kind of method and system for measuring heart rate
GB201516121D0 (en) * 2015-09-11 2015-10-28 Bae Systems Plc Helmet tracker buffering compensation
KR101991412B1 (en) * 2016-12-30 2019-06-20 충북대학교 산학협력단 Method for measuring PPG signal around aortic arch
EP3684463A4 (en) 2017-09-19 2021-06-23 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
US11318277B2 (en) 2017-12-31 2022-05-03 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to enhance emotional response
EP3621055A4 (en) 2018-04-10 2020-12-23 National Aviation Academy Universal virtual simulator
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
WO2020056418A1 (en) 2018-09-14 2020-03-19 Neuroenhancement Lab, LLC System and method of improving sleep
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep

Citations (2)

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US5792051A (en) * 1988-12-21 1998-08-11 Non-Invasive Technology, Inc. Optical probe for non-invasive monitoring of neural activity
US6526297B1 (en) * 1999-10-04 2003-02-25 Instrumentarium Corp. Method and apparatus for quantifying the hypnotic component of the depth of anesthesia by monitoring changes in optical scattering properties of brain tissue

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US5119815A (en) * 1988-12-21 1992-06-09 Nim, Incorporated Apparatus for determining the concentration of a tissue pigment of known absorbance, in vivo, using the decay characteristics of scintered electromagnetic radiation
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US6836680B2 (en) * 2002-01-15 2004-12-28 Leadtek Research Inc. Detector for measuring electrocardiogram, pulse and voice sound at the same time

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
US5792051A (en) * 1988-12-21 1998-08-11 Non-Invasive Technology, Inc. Optical probe for non-invasive monitoring of neural activity
US6526297B1 (en) * 1999-10-04 2003-02-25 Instrumentarium Corp. Method and apparatus for quantifying the hypnotic component of the depth of anesthesia by monitoring changes in optical scattering properties of brain tissue

Also Published As

Publication number Publication date
CA2593538C (en) 2013-01-08
WO2006076361A2 (en) 2006-07-20
US7547284B2 (en) 2009-06-16
CA2593538A1 (en) 2006-07-20
US20080021332A1 (en) 2008-01-24

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