WO2006034432A3 - Electrospray apparatus with an integrated electrode - Google Patents

Electrospray apparatus with an integrated electrode Download PDF

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Publication number
WO2006034432A3
WO2006034432A3 PCT/US2005/034093 US2005034093W WO2006034432A3 WO 2006034432 A3 WO2006034432 A3 WO 2006034432A3 US 2005034093 W US2005034093 W US 2005034093W WO 2006034432 A3 WO2006034432 A3 WO 2006034432A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrospray
planar substrate
methods
microfluidic
integrated
Prior art date
Application number
PCT/US2005/034093
Other languages
French (fr)
Other versions
WO2006034432A2 (en
Inventor
Luc J Bousse
Mingqi Zhao
Original Assignee
Predicant Biosciences Inc
Luc J Bousse
Mingqi Zhao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Predicant Biosciences Inc, Luc J Bousse, Mingqi Zhao filed Critical Predicant Biosciences Inc
Publication of WO2006034432A2 publication Critical patent/WO2006034432A2/en
Publication of WO2006034432A3 publication Critical patent/WO2006034432A3/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • H01J49/167—Capillaries and nozzles specially adapted therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/053—Arrangements for supplying power, e.g. charging power
    • B05B5/0533—Electrodes specially adapted therefor; Arrangements of electrodes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0013—Miniaturised spectrometers, e.g. having smaller than usual scale, integrated conventional components
    • H01J49/0018—Microminiaturised spectrometers, e.g. chip-integrated devices, MicroElectro-Mechanical Systems [MEMS]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/494—Fluidic or fluid actuated device making

Abstract

The invention provides related apparatus and methods of making an integrated electrospray tip (102) by depositing ionic and/or electronic conductor materials onto a planar substrate. The invention also features methods of forming an electrospray apparatus comprising coupling a first planar substrate (104) to the surface of a second planar substrate (105), wherein a surface on at least one of the substrates includes one or more microfluidic channels (109, 112) and/or reservoirs ((108, 113, 114) which are at least partially or totally enclosed therebetween. The conductive regions of the apparatus do not intersect the microfluidic channels (109, 112) within other portions of the apparatus provided preferably. The invention further provides related apparatus and methods for manufacturing and using microfluidic devices (101) with integrated electrodes for electrospray ionization. The electrospray apparatus in some embodiments may include an electronic conductor electrode or an ionic conductor electrode formed from a microfluidic channel (109, 112) containing a conductive material selected from a variety of solutions and gels.
PCT/US2005/034093 2004-09-21 2005-09-21 Electrospray apparatus with an integrated electrode WO2006034432A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61213604P 2004-09-21 2004-09-21
US60/612,136 2004-09-21
US11/031,963 US20060060769A1 (en) 2004-09-21 2005-01-06 Electrospray apparatus with an integrated electrode
US11/031,963 2005-01-06

Publications (2)

Publication Number Publication Date
WO2006034432A2 WO2006034432A2 (en) 2006-03-30
WO2006034432A3 true WO2006034432A3 (en) 2006-08-17

Family

ID=36072940

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/034093 WO2006034432A2 (en) 2004-09-21 2005-09-21 Electrospray apparatus with an integrated electrode

Country Status (2)

Country Link
US (3) US20060060769A1 (en)
WO (1) WO2006034432A2 (en)

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US20070057179A1 (en) 2007-03-15
US20060060769A1 (en) 2006-03-23

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