WO2005119025A3 - Radioactive-emission-measurement optimization to specific body structures - Google Patents

Radioactive-emission-measurement optimization to specific body structures Download PDF

Info

Publication number
WO2005119025A3
WO2005119025A3 PCT/IL2005/000575 IL2005000575W WO2005119025A3 WO 2005119025 A3 WO2005119025 A3 WO 2005119025A3 IL 2005000575 W IL2005000575 W IL 2005000575W WO 2005119025 A3 WO2005119025 A3 WO 2005119025A3
Authority
WO
WIPO (PCT)
Prior art keywords
radioactive
emission
body structures
measurements
views
Prior art date
Application number
PCT/IL2005/000575
Other languages
French (fr)
Other versions
WO2005119025A2 (en
Inventor
Michael Nagler
Eli Dichterman
Yoel Zilberstein
Ran Ravhon
Omer Ziv
Benny Rousso
Shlomo Ben-Haim
Original Assignee
Spectrum Dynamics Llc
Michael Nagler
Eli Dichterman
Yoel Zilberstein
Ran Ravhon
Omer Ziv
Benny Rousso
Shlomo Ben-Haim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP05747259.9A priority Critical patent/EP1778957A4/en
Application filed by Spectrum Dynamics Llc, Michael Nagler, Eli Dichterman, Yoel Zilberstein, Ran Ravhon, Omer Ziv, Benny Rousso, Shlomo Ben-Haim filed Critical Spectrum Dynamics Llc
Priority to PCT/IL2005/001173 priority patent/WO2006051531A2/en
Priority to EP05803158.4A priority patent/EP1827505A4/en
Publication of WO2005119025A2 publication Critical patent/WO2005119025A2/en
Priority to PCT/IL2006/000059 priority patent/WO2006075333A2/en
Priority to US11/794,799 priority patent/US7872235B2/en
Priority to EP06700631.2A priority patent/EP1844351A4/en
Priority to CA002610256A priority patent/CA2610256A1/en
Priority to PCT/IL2006/000562 priority patent/WO2006129301A2/en
Priority to EP06728347.3A priority patent/EP1891597B1/en
Priority to US11/607,075 priority patent/US8094894B2/en
Priority to US11/798,017 priority patent/US8586932B2/en
Publication of WO2005119025A3 publication Critical patent/WO2005119025A3/en
Priority to US12/309,479 priority patent/US9040016B2/en
Priority to US11/980,653 priority patent/US8606349B2/en
Priority to US11/932,987 priority patent/US8620679B2/en
Priority to US11/980,690 priority patent/US8423125B2/en
Priority to US11/980,683 priority patent/US8445851B2/en
Priority to US11/980,617 priority patent/US8000773B2/en
Priority to US12/728,383 priority patent/US7968851B2/en
Priority to US13/345,719 priority patent/US8620046B2/en
Priority to US14/082,314 priority patent/US9316743B2/en
Priority to US14/100,082 priority patent/US9943274B2/en
Priority to US14/140,587 priority patent/US9370333B2/en
Priority to US15/184,041 priority patent/US9943278B2/en
Priority to US15/294,737 priority patent/US10964075B2/en
Priority to US15/953,461 priority patent/US10136865B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/48Diagnostic techniques
    • A61B6/481Diagnostic techniques involving the use of contrast agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/06Diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4266Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a plurality of detector units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/54Control of apparatus or devices for radiation diagnosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/161Applications in the field of nuclear medicine, e.g. in vivo counting
    • G01T1/164Scintigraphy
    • G01T1/1641Static instruments for imaging the distribution of radioactivity in one or two dimensions using one or several scintillating elements; Radio-isotope cameras
    • G01T1/1642Static instruments for imaging the distribution of radioactivity in one or two dimensions using one or several scintillating elements; Radio-isotope cameras using a scintillation crystal and position sensing photodetector arrays, e.g. ANGER cameras
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/161Applications in the field of nuclear medicine, e.g. in vivo counting
    • G01T1/164Scintigraphy
    • G01T1/1641Static instruments for imaging the distribution of radioactivity in one or two dimensions using one or several scintillating elements; Radio-isotope cameras
    • G01T1/1644Static instruments for imaging the distribution of radioactivity in one or two dimensions using one or several scintillating elements; Radio-isotope cameras using an array of optically separate scintillation elements permitting direct location of scintillations
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images

Abstract

Systems, methods, and probes are provided for functional imaging by radioactive-emission-measurements, specfic to body structures, such as the prostate, the esophagus, the cervix, the uterus, the ovaries, the heart, the breast, the brain, and the whole body, and other body structures (fig. 5c element 206). The nuclear imaging may be performed alone, or together with structural imaging, for example, by x-rays, ultrasound, or MRI. Preferably, the radioactive-emission-measuring probes include detectors, which are adapted for individual motions with respect to the probe housings, to generate views from different orientations and to change their view orientations (fig. 5c element 207). These motions are optimized with respect to functional information gained about the body structure, by identifying preferred sets of views for measurements, based on models of the body structures abd information theoretic measures (fig. 5c element 208). A second iteration, for identifying preferred sets of views for measurements of a portion of body structure, based on models of a location of a pathology that has been identified, makes it possible, in effect, to zoom in on a suspected pathology. The systems are programmed to provide these motions automatically.
PCT/IL2005/000575 2000-08-21 2005-06-01 Radioactive-emission-measurement optimization to specific body structures WO2005119025A2 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
EP05747259.9A EP1778957A4 (en) 2004-06-01 2005-06-01 Radioactive-emission-measurement optimization to specific body structures
PCT/IL2005/001173 WO2006051531A2 (en) 2004-11-09 2005-11-09 Radioimaging
EP05803158.4A EP1827505A4 (en) 2004-11-09 2005-11-09 Radioimaging
EP06700631.2A EP1844351A4 (en) 2005-01-13 2006-01-15 Multi-dimensional image reconstruction and analysis for expert-system diagnosis
US11/794,799 US7872235B2 (en) 2005-01-13 2006-01-15 Multi-dimensional image reconstruction and analysis for expert-system diagnosis
PCT/IL2006/000059 WO2006075333A2 (en) 2005-01-13 2006-01-15 Multi-dimensional image reconstruction and analysis for expert-system diagnosis
CA002610256A CA2610256A1 (en) 2005-06-01 2006-05-11 Unified management of radiopharmaceutical dispensing, administration, and imaging
PCT/IL2006/000562 WO2006129301A2 (en) 2005-06-01 2006-05-11 Unified management of radiopharmaceutical dispensing, administration, and imaging
EP06728347.3A EP1891597B1 (en) 2005-06-01 2006-05-11 Unified management of radiopharmaceutical dispensing, administration, and imaging
US11/607,075 US8094894B2 (en) 2000-08-21 2006-12-01 Radioactive-emission-measurement optimization to specific body structures
US11/798,017 US8586932B2 (en) 2004-11-09 2007-05-09 System and method for radioactive emission measurement
US12/309,479 US9040016B2 (en) 2004-01-13 2007-07-19 Diagnostic kit and methods for radioimaging myocardial perfusion
US11/980,617 US8000773B2 (en) 2004-11-09 2007-10-31 Radioimaging
US11/980,653 US8606349B2 (en) 2004-11-09 2007-10-31 Radioimaging using low dose isotope
US11/980,683 US8445851B2 (en) 2004-11-09 2007-10-31 Radioimaging
US11/932,987 US8620679B2 (en) 2004-11-09 2007-10-31 Radiopharmaceutical dispensing, administration, and imaging
US11/980,690 US8423125B2 (en) 2004-11-09 2007-10-31 Radioimaging
US12/728,383 US7968851B2 (en) 2004-01-13 2010-03-22 Dynamic spect camera
US13/345,719 US8620046B2 (en) 2000-08-21 2012-01-08 Radioactive-emission-measurement optimization to specific body structures
US14/082,314 US9316743B2 (en) 2004-11-09 2013-11-18 System and method for radioactive emission measurement
US14/100,082 US9943274B2 (en) 2004-11-09 2013-12-09 Radioimaging using low dose isotope
US14/140,587 US9370333B2 (en) 2000-08-21 2013-12-26 Radioactive-emission-measurement optimization to specific body structures
US15/184,041 US9943278B2 (en) 2004-06-01 2016-06-16 Radioactive-emission-measurement optimization to specific body structures
US15/294,737 US10964075B2 (en) 2004-01-13 2016-10-16 Gating with anatomically varying durations
US15/953,461 US10136865B2 (en) 2004-11-09 2018-04-15 Radioimaging using low dose isotope

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
US57536904P 2004-06-01 2004-06-01
US60/575,369 2004-06-01
US62597104P 2004-11-09 2004-11-09
US60/625,971 2004-11-09
US63056104P 2004-11-26 2004-11-26
US60/630,561 2004-11-26
US63223604P 2004-12-02 2004-12-02
US60/632,236 2004-12-02
US63251504P 2004-12-03 2004-12-03
US60/632,515 2004-12-03
US63563004P 2004-12-14 2004-12-14
US60/635,630 2004-12-14
US63608804P 2004-12-16 2004-12-16
US60/636,088 2004-12-16
US64021505P 2005-01-03 2005-01-03
US60/640,215 2005-01-03
US64838505P 2005-02-01 2005-02-01
US60/648,385 2005-02-01
US64869005P 2005-02-02 2005-02-02
US60/648,690 2005-02-02

Related Parent Applications (4)

Application Number Title Priority Date Filing Date
US09/641,973 Continuation-In-Part US8489176B1 (en) 2000-08-21 2000-08-21 Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
PCT/IL2005/000048 Continuation-In-Part WO2005067383A2 (en) 2004-01-13 2005-01-13 Multi-dimensional image reconstruction
PCT/IL2005/000572 Continuation-In-Part WO2005118659A2 (en) 2004-01-13 2005-06-01 Methods of view selection for radioactive emission measurements
US11/798,017 Continuation-In-Part US8586932B2 (en) 2004-01-13 2007-05-09 System and method for radioactive emission measurement

Related Child Applications (3)

Application Number Title Priority Date Filing Date
PCT/IL2005/000572 Continuation-In-Part WO2005118659A2 (en) 2004-01-13 2005-06-01 Methods of view selection for radioactive emission measurements
PCT/IL2005/001173 Continuation-In-Part WO2006051531A2 (en) 2004-01-13 2005-11-09 Radioimaging
US11/607,075 Continuation-In-Part US8094894B2 (en) 2000-08-21 2006-12-01 Radioactive-emission-measurement optimization to specific body structures

Publications (2)

Publication Number Publication Date
WO2005119025A2 WO2005119025A2 (en) 2005-12-15
WO2005119025A3 true WO2005119025A3 (en) 2007-07-05

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2005/000575 WO2005119025A2 (en) 2000-08-21 2005-06-01 Radioactive-emission-measurement optimization to specific body structures

Country Status (3)

Country Link
US (4) US8094894B2 (en)
EP (1) EP1778957A4 (en)
WO (1) WO2005119025A2 (en)

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US8620046B2 (en) 2013-12-31
EP1778957A4 (en) 2015-12-23
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US9943278B2 (en) 2018-04-17
US20120172699A1 (en) 2012-07-05
US9370333B2 (en) 2016-06-21
US20170007193A1 (en) 2017-01-12
US20070156047A1 (en) 2007-07-05
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US8094894B2 (en) 2012-01-10
US20140187927A1 (en) 2014-07-03

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