WO2005107404A3 - Methods and systems for nanoparticle enhancement of signals - Google Patents
Methods and systems for nanoparticle enhancement of signals Download PDFInfo
- Publication number
- WO2005107404A3 WO2005107404A3 PCT/US2005/015344 US2005015344W WO2005107404A3 WO 2005107404 A3 WO2005107404 A3 WO 2005107404A3 US 2005015344 W US2005015344 W US 2005015344W WO 2005107404 A3 WO2005107404 A3 WO 2005107404A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- systems
- methods
- signals
- nanoparticle
- enhancement
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56770704P | 2004-05-03 | 2004-05-03 | |
US60/567,707 | 2004-05-03 | ||
US58590504P | 2004-07-07 | 2004-07-07 | |
US60/585,905 | 2004-07-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005107404A2 WO2005107404A2 (en) | 2005-11-17 |
WO2005107404A3 true WO2005107404A3 (en) | 2006-05-11 |
Family
ID=35320651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/015344 WO2005107404A2 (en) | 2004-05-03 | 2005-05-03 | Methods and systems for nanoparticle enhancement of signals |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005107404A2 (en) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849513A (en) * | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
US5525711A (en) * | 1994-05-18 | 1996-06-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Pteridine nucleotide analogs as fluorescent DNA probes |
US6361944B1 (en) * | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US20040099813A1 (en) * | 2000-12-21 | 2004-05-27 | Christian Eggeling | Method for characterizing samples of secondary light emitting particles |
US20050059042A1 (en) * | 2003-05-16 | 2005-03-17 | Rothberg Lewis J. | Colorimetric and fluorescent methods for sensing of oligonucleotides |
US20050074779A1 (en) * | 2003-10-02 | 2005-04-07 | Tuan Vo-Dinh | SERS molecular probe for diagnostics and therapy |
US6878814B2 (en) * | 1996-07-29 | 2005-04-12 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
-
2005
- 2005-05-03 WO PCT/US2005/015344 patent/WO2005107404A2/en active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849513A (en) * | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
US5525711A (en) * | 1994-05-18 | 1996-06-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Pteridine nucleotide analogs as fluorescent DNA probes |
US6361944B1 (en) * | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US6878814B2 (en) * | 1996-07-29 | 2005-04-12 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US20040099813A1 (en) * | 2000-12-21 | 2004-05-27 | Christian Eggeling | Method for characterizing samples of secondary light emitting particles |
US20050059042A1 (en) * | 2003-05-16 | 2005-03-17 | Rothberg Lewis J. | Colorimetric and fluorescent methods for sensing of oligonucleotides |
US20050074779A1 (en) * | 2003-10-02 | 2005-04-07 | Tuan Vo-Dinh | SERS molecular probe for diagnostics and therapy |
Also Published As
Publication number | Publication date |
---|---|
WO2005107404A2 (en) | 2005-11-17 |
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