WO2005100604A8 - Methods for identifying risk of osteoarthritis and treatments thereof - Google Patents

Methods for identifying risk of osteoarthritis and treatments thereof

Info

Publication number: WO2005100604A8
Authority: WO; WIPO (PCT)
Prior art keywords: osteoarthritis; treatments; methods; identifying risk; identifying
Prior art date: 2004-04-01

Application number

PCT/US2005/010912

Other languages

French (fr)

Other versions

WO2005100604A2 (en

Inventor

Steven Mah

Andreas Braun

Stefan M Kammerer

Matthew Roberts Nelson

Rikard Henry Reneland

Maria L Langdown

Original Assignee

Sequenom Inc

Steven Mah

Andreas Braun

Stefan M Kammerer

Matthew Roberts Nelson

Rikard Henry Reneland

Maria L Langdown

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-01

Filing date

2005-03-31

Publication date

2006-03-09

2005-03-31 Application filed by Sequenom Inc, Steven Mah, Andreas Braun, Stefan M Kammerer, Matthew Roberts Nelson, Rikard Henry Reneland, Maria L Langdown filed Critical Sequenom Inc

2005-03-31 Priority to EP05768810A priority Critical patent/EP1756317A4/en

2005-03-31 Priority to CA002561742A priority patent/CA2561742A1/en

2005-10-27 Publication of WO2005100604A2 publication Critical patent/WO2005100604A2/en

2006-03-09 Publication of WO2005100604A8 publication Critical patent/WO2005100604A8/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone

PCT/US2005/010912 2004-04-01 2005-03-31 Methods for identifying risk of osteoarthritis and treatments thereof WO2005100604A2 (en)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
EP05768810A EP1756317A4 (en)	2004-04-01	2005-03-31	Methods for identifying risk of osteoarthritis and treatments thereof
CA002561742A CA2561742A1 (en)	2004-04-01	2005-03-31	Methods for identifying risk of osteoarthritis and treatments thereof

Applications Claiming Priority (14)

Application Number	Priority Date	Filing Date
US55927504P	2004-04-01	2004-04-01
US55920304P	2004-04-01	2004-04-01
US55920204P	2004-04-01	2004-04-01
US55901104P	2004-04-01	2004-04-01
US55922504P	2004-04-01	2004-04-01
US55904204P	2004-04-01	2004-04-01
US55904004P	2004-04-01	2004-04-01
US60/559,042		2004-04-01
US60/559,202		2004-04-01
US60/559,275		2004-04-01
US60/559,011		2004-04-01
US60/559,203		2004-04-01
US60/559,040		2004-04-01
US60/559,225		2004-04-01

Publications (2)

Publication Number	Publication Date
WO2005100604A2 WO2005100604A2 (en)	2005-10-27
WO2005100604A8 true WO2005100604A8 (en)	2006-03-09

Family

ID=35125645

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PCT/US2005/010912 WO2005100604A2 (en)	2004-04-01	2005-03-31	Methods for identifying risk of osteoarthritis and treatments thereof
PCT/US2005/010913 WO2005097421A2 (en)	2004-04-01	2005-03-31	Methods for identifying risk of osteoarthritis and treatments thereof

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PCT/US2005/010913 WO2005097421A2 (en)	2004-04-01	2005-03-31	Methods for identifying risk of osteoarthritis and treatments thereof

Country Status (3)

Country	Link
EP (2)	EP1756317A4 (en)
CA (2)	CA2561742A1 (en)
WO (2)	WO2005100604A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8461303B2 (en)	2007-08-02	2013-06-11	Gilead Biologics, Inc.	LOX and LOXL2 inhibitors and uses thereof
US8927700B2 (en)	2009-08-21	2015-01-06	Gilead Biologics, Inc.	Catalytic domains from lysyl oxidase and LOXL2
US9107935B2 (en)	2009-01-06	2015-08-18	Gilead Biologics, Inc.	Chemotherapeutic methods and compositions
US11965029B2 (en)	2012-05-18	2024-04-23	Amgen Inc.	ST2 antigen binding proteins

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030114410A1 (en)	2000-08-08	2003-06-19	Technion Research And Development Foundation Ltd.	Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
WO2010071405A1 (en) *	2008-12-18	2010-06-24	Erasmus University Medical Center Rotterdam	Markers for detecting predisposition for risk, incidence and progression of osteoarthritis
WO2019210080A1 (en) *	2018-04-25	2019-10-31	The Regents Of The University Of California	Methods and compositions for skeletal and neurological disorders
CA3102360A1 (en) *	2018-06-20	2019-12-26	Pharma Foods International Co., Ltd.	Novel anti-pad2 antibody
WO2020018503A2 (en)	2018-07-16	2020-01-23	Regeneron Pharmaceuticals, Inc.	Anti-il36r antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003054166A2 (en) *	2001-12-20	2003-07-03	Incyte Genomics, Inc.	Nucleotide polymorphisms associated with osteoarthritis

2005
- 2005-03-31 EP EP05768810A patent/EP1756317A4/en not_active Withdrawn
- 2005-03-31 WO PCT/US2005/010912 patent/WO2005100604A2/en active Application Filing
- 2005-03-31 CA CA002561742A patent/CA2561742A1/en not_active Abandoned
- 2005-03-31 WO PCT/US2005/010913 patent/WO2005097421A2/en active Application Filing
- 2005-03-31 EP EP05763391A patent/EP1729930A2/en not_active Withdrawn
- 2005-03-31 CA CA002561669A patent/CA2561669A1/en not_active Abandoned

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8461303B2 (en)	2007-08-02	2013-06-11	Gilead Biologics, Inc.	LOX and LOXL2 inhibitors and uses thereof
US8679485B2 (en)	2007-08-02	2014-03-25	Gilead Biologics, Inc.	Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis, and metastasis
US9176139B2 (en)	2007-08-02	2015-11-03	Gilead Biologics, Inc.	LOX and LOXL2 inhibitors and uses thereof
US9107935B2 (en)	2009-01-06	2015-08-18	Gilead Biologics, Inc.	Chemotherapeutic methods and compositions
US9289447B2 (en)	2009-01-06	2016-03-22	Gilead Biologics, Inc.	Chemotherapeutic methods and compositions
US8927700B2 (en)	2009-08-21	2015-01-06	Gilead Biologics, Inc.	Catalytic domains from lysyl oxidase and LOXL2
US11965029B2 (en)	2012-05-18	2024-04-23	Amgen Inc.	ST2 antigen binding proteins

Also Published As

Publication number	Publication date
WO2005100604A2 (en)	2005-10-27
CA2561742A1 (en)	2005-10-27
WO2005097421A9 (en)	2010-01-14
WO2005097421A2 (en)	2005-10-20
CA2561669A1 (en)	2005-10-20
EP1756317A2 (en)	2007-02-28
EP1756317A4 (en)	2008-05-28
EP1729930A2 (en)	2006-12-13

Legal Events

Date	Code	Title	Description
2005-10-27	AK	Designated states	Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW
2005-10-27	AL	Designated countries for regional patents	Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG
2005-12-21	121	Ep: the epo has been informed by wipo that ep was designated in this application
2006-03-09	D17	Declaration under article 17(2)a
2006-09-28	WWE	Wipo information: entry into national phase	Ref document number: 2561742 Country of ref document: CA
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