WO2005043121A3 - Blood test prototypes and methods for the detection of circulating tumor and endothelial cells - Google Patents
Blood test prototypes and methods for the detection of circulating tumor and endothelial cells Download PDFInfo
- Publication number
- WO2005043121A3 WO2005043121A3 PCT/US2004/036177 US2004036177W WO2005043121A3 WO 2005043121 A3 WO2005043121 A3 WO 2005043121A3 US 2004036177 W US2004036177 W US 2004036177W WO 2005043121 A3 WO2005043121 A3 WO 2005043121A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- cells
- fetal
- cardiovascular
- metastatic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0093—Purging against cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/75—Fibrin; Fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04796843A EP1706720A4 (en) | 2003-10-31 | 2004-10-30 | Blood test prototypes and methods for the detection of circulating tumor and endothelial cells |
AU2004286307A AU2004286307A1 (en) | 2003-10-31 | 2004-10-30 | Blood test prototypes and methods for the detection of circulating tumor and endothelial cells |
JP2006538370A JP2007526761A (en) | 2003-10-31 | 2004-10-30 | Blood test prototypes and methods for the detection of circulating tumor cells and endothelial cells |
CA002544373A CA2544373A1 (en) | 2003-10-31 | 2004-10-30 | Blood test prototypes and methods for the detection of circulating tumor and endothelial cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51657103P | 2003-10-31 | 2003-10-31 | |
US60/516,571 | 2003-10-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005043121A2 WO2005043121A2 (en) | 2005-05-12 |
WO2005043121A3 true WO2005043121A3 (en) | 2006-08-24 |
Family
ID=34549552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/036177 WO2005043121A2 (en) | 2003-10-31 | 2004-10-30 | Blood test prototypes and methods for the detection of circulating tumor and endothelial cells |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1706720A4 (en) |
JP (1) | JP2007526761A (en) |
CN (2) | CN1922304A (en) |
AU (1) | AU2004286307A1 (en) |
CA (1) | CA2544373A1 (en) |
HK (1) | HK1209778A1 (en) |
WO (1) | WO2005043121A2 (en) |
Cited By (6)
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US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
US8168389B2 (en) | 2006-06-14 | 2012-05-01 | The General Hospital Corporation | Fetal cell analysis using sample splitting |
US8195415B2 (en) | 2008-09-20 | 2012-06-05 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US8986966B2 (en) | 2002-09-27 | 2015-03-24 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
US9174222B2 (en) | 2005-04-05 | 2015-11-03 | The General Hospital Corporation | Devices and method for enrichment and alteration of cells and other particles |
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US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
US7910315B2 (en) | 2004-09-10 | 2011-03-22 | The Regents Of The University Of Colorado, A Body Corporate | Early detection of hemangiosarcoma and angiosarcoma |
US7769547B2 (en) * | 2005-11-01 | 2010-08-03 | David S. Alberts | Karyometry-based method for prediction of cancer event recurrence |
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US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
US20080070792A1 (en) | 2006-06-14 | 2008-03-20 | Roland Stoughton | Use of highly parallel snp genotyping for fetal diagnosis |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4829000A (en) * | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
US5840514A (en) * | 1996-11-21 | 1998-11-24 | The Regents Of The University Of Michigan | Methods of testing cancer and anticancer drugs |
US6060317A (en) * | 1998-08-11 | 2000-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Method of transducing mammalian cells, and products related thereto |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4092246A (en) * | 1975-05-16 | 1978-05-30 | Abcor, Inc. | Helically wound blood filter |
US5147797A (en) * | 1987-08-25 | 1992-09-15 | Regents Of The University Of Minnesota | Polypeptides with fibronectin activity |
EP0784499A4 (en) * | 1992-09-11 | 2000-03-29 | Xenogenex Inc | Artificial liver apparatus and method |
FI93742C (en) * | 1992-10-23 | 1995-05-26 | Elias Hakalehto | Method and apparatus for detecting cells |
ATE237676T1 (en) * | 1995-02-16 | 2003-05-15 | Forschungszentrum Juelich Gmbh | METHOD FOR CULTIVATION OF ORGAN FUNCTIONAL CELLS |
GB9704444D0 (en) * | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
JPH11127843A (en) * | 1997-10-27 | 1999-05-18 | Sumitomo Bakelite Co Ltd | Colored container for culture |
MXPA01002674A (en) * | 1998-09-14 | 2002-06-04 | Ostergaard Pedersen Lars | A method of producing a functional immunoglobulin superfamily protein. |
JP5433840B2 (en) * | 2000-09-09 | 2014-03-05 | ザ・リサーチ・ファウンデーション・フォー・ザ・ステイト・ユニヴァーシティ・オブ・ニューヨーク | Methods and compositions for isolating metastatic cancer cells and their use in measuring the metastatic potential of cancer |
GB0025245D0 (en) * | 2000-10-14 | 2000-11-29 | Lee Helen | Multiple target detection |
CN1118563C (en) * | 2000-12-08 | 2003-08-20 | 中国医学科学院血液学研究所 | Hematopoietic device using hollow fibre to simulate bone marrow |
WO2003035888A1 (en) * | 2001-08-28 | 2003-05-01 | Wen-Tien Chen | Cell separation matrix |
EP1409745B1 (en) * | 2001-09-06 | 2007-04-11 | Adnagen AG | Method and kit for the diagnosis or treatment control of intestinal carcinoma |
-
2004
- 2004-10-30 WO PCT/US2004/036177 patent/WO2005043121A2/en active Application Filing
- 2004-10-30 CN CNA2004800393630A patent/CN1922304A/en active Pending
- 2004-10-30 AU AU2004286307A patent/AU2004286307A1/en not_active Abandoned
- 2004-10-30 CA CA002544373A patent/CA2544373A1/en not_active Abandoned
- 2004-10-30 JP JP2006538370A patent/JP2007526761A/en active Pending
- 2004-10-30 CN CN201410710695.2A patent/CN104531529A/en active Pending
- 2004-10-30 EP EP04796843A patent/EP1706720A4/en not_active Withdrawn
-
2015
- 2015-10-22 HK HK15110407.9A patent/HK1209778A1/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4829000A (en) * | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
US5840514A (en) * | 1996-11-21 | 1998-11-24 | The Regents Of The University Of Michigan | Methods of testing cancer and anticancer drugs |
US6060317A (en) * | 1998-08-11 | 2000-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Method of transducing mammalian cells, and products related thereto |
Non-Patent Citations (2)
Title |
---|
HOCKING D. ET AL.: "Activation of Distinct Alpha5Beta - mediated Signaling PAthway by Fibronectin's Cell Adhesion and MAtrix Assembly Domains.", JOURNAL OF CELL BIOLOGY, vol. 141, no. 1, 6 April 1998 (1998-04-06), pages 241 - 253, XP003010319 * |
See also references of EP1706720A4 * |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8986966B2 (en) | 2002-09-27 | 2015-03-24 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
US9174222B2 (en) | 2005-04-05 | 2015-11-03 | The General Hospital Corporation | Devices and method for enrichment and alteration of cells and other particles |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US8372584B2 (en) | 2006-06-14 | 2013-02-12 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
US9017942B2 (en) | 2006-06-14 | 2015-04-28 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
US8168389B2 (en) | 2006-06-14 | 2012-05-01 | The General Hospital Corporation | Fetal cell analysis using sample splitting |
US9273355B2 (en) | 2006-06-14 | 2016-03-01 | The General Hospital Corporation | Rare cell analysis using sample splitting and DNA tags |
US9347100B2 (en) | 2006-06-14 | 2016-05-24 | Gpb Scientific, Llc | Rare cell analysis using sample splitting and DNA tags |
US8296076B2 (en) | 2008-09-20 | 2012-10-23 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuoploidy by sequencing |
US8682594B2 (en) | 2008-09-20 | 2014-03-25 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US8195415B2 (en) | 2008-09-20 | 2012-06-05 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US9353414B2 (en) | 2008-09-20 | 2016-05-31 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US9404157B2 (en) | 2008-09-20 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
Also Published As
Publication number | Publication date |
---|---|
HK1209778A1 (en) | 2016-04-08 |
CN1922304A (en) | 2007-02-28 |
JP2007526761A (en) | 2007-09-20 |
EP1706720A2 (en) | 2006-10-04 |
CA2544373A1 (en) | 2005-05-12 |
WO2005043121A2 (en) | 2005-05-12 |
AU2004286307A1 (en) | 2005-05-12 |
CN104531529A (en) | 2015-04-22 |
EP1706720A4 (en) | 2007-02-28 |
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