WO2005043117A3 - Gel-shell beads with adsorbed or bound biomolecules - Google Patents

Gel-shell beads with adsorbed or bound biomolecules Download PDF

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Publication number
WO2005043117A3
WO2005043117A3 PCT/US2004/035437 US2004035437W WO2005043117A3 WO 2005043117 A3 WO2005043117 A3 WO 2005043117A3 US 2004035437 W US2004035437 W US 2004035437W WO 2005043117 A3 WO2005043117 A3 WO 2005043117A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel
adsorbed
biomolecules
beads
coated
Prior art date
Application number
PCT/US2004/035437
Other languages
French (fr)
Other versions
WO2005043117A2 (en
Inventor
Sukanta Banerjee
Enqing Tan
Original Assignee
Bioarray Solutions Ltd
Sukanta Banerjee
Enqing Tan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioarray Solutions Ltd, Sukanta Banerjee, Enqing Tan filed Critical Bioarray Solutions Ltd
Priority to JP2006538168A priority Critical patent/JP2007518065A/en
Priority to AU2004286253A priority patent/AU2004286253A1/en
Priority to EP04817450A priority patent/EP1682866A4/en
Priority to NZ547494A priority patent/NZ547494A/en
Priority to CA002544262A priority patent/CA2544262A1/en
Publication of WO2005043117A2 publication Critical patent/WO2005043117A2/en
Priority to IL175184A priority patent/IL175184A0/en
Publication of WO2005043117A3 publication Critical patent/WO2005043117A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase

Abstract

Disclosed are gel-coated beads (including HydrogelTM -coated beads), which are capable of adsorbing, or absorbing, proteins and other biomolecules onto or into the gel coating. The gel­coated beads with absorbed or adsorbed biomolecules are suitable for use in an assays, purification or other purposes. The beads have a core made from any of a number of materials, including latex, coated with the gel shell. The biomolecules can be retained within the gel, following adsorption, by covalent attachment, or, by selection of conditions of ambient pH and/or ionic strength such that they are retained without further reaction. Therefore, adsorbed proteins would retain the ability to bind to their respective ligands.
PCT/US2004/035437 2003-10-28 2004-10-26 Gel-shell beads with adsorbed or bound biomolecules WO2005043117A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2006538168A JP2007518065A (en) 2003-10-28 2004-10-26 Gel-shell beads with adsorbed or bound biomolecules
AU2004286253A AU2004286253A1 (en) 2003-10-28 2004-10-26 Gel-shell beads with adsorbed or bound biomolecules
EP04817450A EP1682866A4 (en) 2003-10-28 2004-10-26 Gel-shell beads with adsorbed or bound biomolecules
NZ547494A NZ547494A (en) 2003-10-28 2004-10-26 Gel-shell beads with absorbed or bound biomolecules
CA002544262A CA2544262A1 (en) 2003-10-28 2004-10-26 Gel-shell beads with adsorbed or bound biomolecules
IL175184A IL175184A0 (en) 2003-10-28 2006-04-25 Gel- shell beads with adsorbed or bound biomolecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51507903P 2003-10-28 2003-10-28
US60/515,079 2003-10-28

Publications (2)

Publication Number Publication Date
WO2005043117A2 WO2005043117A2 (en) 2005-05-12
WO2005043117A3 true WO2005043117A3 (en) 2006-08-17

Family

ID=34549373

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/035437 WO2005043117A2 (en) 2003-10-28 2004-10-26 Gel-shell beads with adsorbed or bound biomolecules

Country Status (10)

Country Link
US (1) US7582488B2 (en)
EP (1) EP1682866A4 (en)
JP (1) JP2007518065A (en)
CN (1) CN1905806A (en)
AU (1) AU2004286253A1 (en)
CA (1) CA2544262A1 (en)
IL (1) IL175184A0 (en)
NZ (1) NZ547494A (en)
TW (1) TW200517651A (en)
WO (1) WO2005043117A2 (en)

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Also Published As

Publication number Publication date
CA2544262A1 (en) 2005-05-12
NZ547494A (en) 2008-05-30
IL175184A0 (en) 2006-09-05
JP2007518065A (en) 2007-07-05
EP1682866A4 (en) 2008-03-12
WO2005043117A2 (en) 2005-05-12
CN1905806A (en) 2007-01-31
TW200517651A (en) 2005-06-01
AU2004286253A1 (en) 2005-05-12
EP1682866A2 (en) 2006-07-26
US20050112655A1 (en) 2005-05-26
US7582488B2 (en) 2009-09-01

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