WO2005033654A3 - Micro flow cytometer with multiangular waveguide detectors having spectral capabilities - Google Patents

Micro flow cytometer with multiangular waveguide detectors having spectral capabilities Download PDF

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Publication number
WO2005033654A3
WO2005033654A3 PCT/US2004/028175 US2004028175W WO2005033654A3 WO 2005033654 A3 WO2005033654 A3 WO 2005033654A3 US 2004028175 W US2004028175 W US 2004028175W WO 2005033654 A3 WO2005033654 A3 WO 2005033654A3
Authority
WO
WIPO (PCT)
Prior art keywords
flow cytometer
micro flow
multiangular
light
spectral capabilities
Prior art date
Application number
PCT/US2004/028175
Other languages
French (fr)
Other versions
WO2005033654A2 (en
Inventor
Yi-Chung Tung
Chih-Ting Lin
Katsuo Kurabayashi
Steven J Skerlos
Min Zhang
Original Assignee
Univ Michigan
Yi-Chung Tung
Chih-Ting Lin
Katsuo Kurabayashi
Steven J Skerlos
Min Zhang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan, Yi-Chung Tung, Chih-Ting Lin, Katsuo Kurabayashi, Steven J Skerlos, Min Zhang filed Critical Univ Michigan
Publication of WO2005033654A2 publication Critical patent/WO2005033654A2/en
Publication of WO2005033654A3 publication Critical patent/WO2005033654A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N15/1436—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1484—Electro-optical investigation, e.g. flow cytometers microstructural devices

Abstract

A micro flow cytometer having the ability to distinguish light emanating from a particle in the interrogation zone (6) of the cytometer contains a plurality of optical waveguides (10, 11, 12, 13) for receiving emanating light, the optical waveguides (10, 11, 12, 13) positioned at different angles from the axis of the interrogation zone and in the same plane. Photodetectors measuring emanated light provide an electrical signal which is processable to reveal an angular dependence of wavelength with respect to the interrogation channel (6).
PCT/US2004/028175 2003-08-28 2004-08-30 Micro flow cytometer with multiangular waveguide detectors having spectral capabilities WO2005033654A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49845303P 2003-08-28 2003-08-28
US60/498,453 2003-08-28

Publications (2)

Publication Number Publication Date
WO2005033654A2 WO2005033654A2 (en) 2005-04-14
WO2005033654A3 true WO2005033654A3 (en) 2006-02-16

Family

ID=34421488

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/028175 WO2005033654A2 (en) 2003-08-28 2004-08-30 Micro flow cytometer with multiangular waveguide detectors having spectral capabilities

Country Status (1)

Country Link
WO (1) WO2005033654A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7551278B2 (en) 2006-05-12 2009-06-23 Honeywell International Inc. Fluid light guide system
US20100220315A1 (en) * 2009-02-27 2010-09-02 Beckman Coulter, Inc. Stabilized Optical System for Flow Cytometry
US8907312B2 (en) * 2010-08-20 2014-12-09 Bio-Rad Laboratories, Inc. Cytometry system with solid numerical-aperture-increasing lens
US9176055B2 (en) 2012-01-04 2015-11-03 Sony Corporation System and method for measuring narrow and wide angle light scatter on a high-speed cell sorting device
US9746412B2 (en) 2012-05-30 2017-08-29 Iris International, Inc. Flow cytometer
JP2015525343A (en) * 2012-05-30 2015-09-03 アイリス インターナショナル インコーポレイテッド Flow cytometer
CN111982790A (en) * 2020-08-24 2020-11-24 深圳唯公生物科技有限公司 Weak light analysis system and method for improving performance of cell and particle analyzer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726751A (en) * 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
US5747349A (en) * 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US20050068536A1 (en) * 2001-12-12 2005-03-31 Schwabe Nikolai Franz Gregor Device and method for investigating analytes in liquid suspension or solution

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726751A (en) * 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
US5747349A (en) * 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US20050068536A1 (en) * 2001-12-12 2005-03-31 Schwabe Nikolai Franz Gregor Device and method for investigating analytes in liquid suspension or solution

Also Published As

Publication number Publication date
WO2005033654A2 (en) 2005-04-14

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