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Publication numberWO2005026729 A3
Publication typeApplication
Application numberPCT/US2004/030300
Publication date30 Jun 2005
Filing date13 Sep 2004
Priority date12 Sep 2003
Also published asCA2538801A1, EP1664782A2, US7164533, US7659983, US7843567, US8049893, US20040263923, US20080129990, US20100099574, US20110058172, WO2005026729A2
Publication numberPCT/2004/30300, PCT/US/2004/030300, PCT/US/2004/30300, PCT/US/4/030300, PCT/US/4/30300, PCT/US2004/030300, PCT/US2004/30300, PCT/US2004030300, PCT/US200430300, PCT/US4/030300, PCT/US4/30300, PCT/US4030300, PCT/US430300, WO 2005/026729 A3, WO 2005026729 A3, WO 2005026729A3, WO-A3-2005026729, WO2005/026729A3, WO2005026729 A3, WO2005026729A3
InventorsTuo Li, John A Moon, Michel Perbost, Martin A Putnam, Joseph Traynor
ApplicantCyvera Corp
Export CitationBiBTeX, EndNote, RefMan
External Links: Patentscope, Espacenet
Improved method and apparatus for aligning microbeads in order to interrogate the same
WO 2005026729 A3
Abstract
A method and apparatus are provided for aligning optical elements or microbeads (8), wherein each microbead has an elongated body with a code embedded therein along a longitudinal axis thereof to be read by a code reading device. The microbeads (8) are aligned with a positioning device (or cell) (500) having a plate or platform (200, 1252) with grooves (205, 1258) so the longitudinal axis of the microbeads is positioned in a fixed orientation relative to the code reading device. The microbeads (8) are typically cylindrically shaped glass beads having a diffraction grating-based code embedded in the bead (8) disposed along an axis, which requires a predetermined alignment between the incident code readout laser beam and the code readout detector in two of three rotational axes. The geometry of the grooves (205) are designed to allow for easy loading and unloading of beads from a cell, and the grooves (205) may be straight or curved. Also, the cell may be segmented into regions each associated with a different reaction or used for a different identification process/ application, and may have many different geometries depending on the application.
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
WO2000016893A2 *17 Sep 199930 Mar 2000Smartbead Technologies LimitedBio-assay technique
WO2000061198A1 *11 Apr 200019 Oct 2000Hitachi Chemical Co., Ltd.Method of producing probe arrays for biological materials using fine particles
US6340588 *3 Oct 199622 Jan 2002Discovery Partners International, Inc.Matrices with memories
US20020039732 *22 Mar 20014 Apr 2002Bruchez Marcel P.Loop probe hybridization assay for polynucleotide analysis
Non-Patent Citations
Reference
1 *JAIN K K: "NANODIAGNOSTICS: APPLICATION OF NANOTECHNOLOGY IN MOLECULAR DIAGNOSTICS" EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, FUTURE DRUGS, LONDON, GB, vol. 3, no. 2, March 2003 (2003-03), pages 153-161, XP008038849 ISSN: 1473-7159
2 *YUEN PO KI ET AL: "Microbarcode sorting device." LAB ON A CHIP. AUG 2003, vol. 3, no. 3, August 2003 (2003-08), pages 198-201, XP009047193 ISSN: 1473-0197
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US765998330 Nov 20069 Feb 2010Electronics And Telecommunications Resarch InstituteHybrid random bead/chip based microarray
US783057510 Apr 20079 Nov 2010Illumina, Inc.Optical scanner with improved scan time
US787280410 Oct 200618 Jan 2011Illumina, Inc.Encoded particle having a grating with variations in the refractive index
US789873521 Mar 20081 Mar 2011Illumina, Inc.Methods and systems for writing an optical code within or on a fiber substrate
US790163013 Sep 20058 Mar 2011Illumina, Inc.Diffraction grating-based encoded microparticle assay stick
US79232606 Oct 200612 Apr 2011Illumina, Inc.Method of reading encoded particles
US808179216 Nov 200520 Dec 2011Illumina, Inc.Fourier scattering methods for encoding microbeads and methods and apparatus for reading the same
US92689834 Oct 201323 Feb 2016Illumina, Inc.Optical system and method for reading encoded microbeads
Classifications
International ClassificationG06K19/00, G03H1/00, G02B6/34, G02B5/18, G06K19/06, G06T5/00, G06K9/18, G01N33/552, B01J19/00, G01N33/543
Cooperative ClassificationG01N33/54313, G03H2250/12, G03H1/26, G01N33/54366, G01N21/6452, G03H1/0236, G01N21/7743, G03H1/0005, G01N33/54306, G01N21/4788, G03H2001/0044, G01N21/6428, G03H2210/63, G03H1/02, G01N21/645, G01N33/54386, G03H2230/10, G06K19/06009, G01N33/552, G03H2210/53, G06K19/04, G03H2001/0033
European ClassificationG03H1/02F, G01N21/64P2, G01N33/543K4, G03H1/02, G03H1/26, G01N21/64H, G01N21/47H, G06K19/04, G01N21/77B3A, G06K19/06C, G01N21/64P, G03H1/00A, G01N33/543B, G01N33/552, G01N33/543K, G01N33/543D
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