WO2004105947A2 - Localized temperature control for spatial arrays of reaction media - Google Patents
Localized temperature control for spatial arrays of reaction media Download PDFInfo
- Publication number
- WO2004105947A2 WO2004105947A2 PCT/US2004/016025 US2004016025W WO2004105947A2 WO 2004105947 A2 WO2004105947 A2 WO 2004105947A2 US 2004016025 W US2004016025 W US 2004016025W WO 2004105947 A2 WO2004105947 A2 WO 2004105947A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- heat
- thermal
- regions
- thermoelectric modules
- wells
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/54—Heating or cooling apparatus; Heat insulating devices using spatial temperature gradients
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1883—Means for temperature control using thermal insulation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE04752947T DE04752947T1 (en) | 2003-05-23 | 2004-05-20 | LOCALIZED TEMPERATURE CONTROL FOR ROOM ARRANGEMENTS OF REACTION MEDIA |
CA2523040A CA2523040C (en) | 2003-05-23 | 2004-05-20 | Localized temperature control for spatial arrays of reaction media |
EP04752947.4A EP1641563B1 (en) | 2003-05-23 | 2004-05-20 | Localized temperature control for spatial arrays of reaction media |
AU2004243070A AU2004243070B2 (en) | 2003-05-23 | 2004-05-20 | Localized temperature control for spatial arrays of reaction media |
JP2006533292A JP4705035B2 (en) | 2003-05-23 | 2004-05-20 | Localized temperature control for spatial arrangement of reaction medium |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47296403P | 2003-05-23 | 2003-05-23 | |
US60/472,964 | 2003-05-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004105947A2 true WO2004105947A2 (en) | 2004-12-09 |
WO2004105947A3 WO2004105947A3 (en) | 2005-12-22 |
Family
ID=33490545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/016025 WO2004105947A2 (en) | 2003-05-23 | 2004-05-20 | Localized temperature control for spatial arrays of reaction media |
Country Status (7)
Country | Link |
---|---|
US (4) | US7771933B2 (en) |
EP (1) | EP1641563B1 (en) |
JP (1) | JP4705035B2 (en) |
AU (1) | AU2004243070B2 (en) |
CA (1) | CA2523040C (en) |
DE (1) | DE04752947T1 (en) |
WO (1) | WO2004105947A2 (en) |
Cited By (25)
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EP1710017A1 (en) | 2005-04-04 | 2006-10-11 | Roche Diagnostics GmbH | Thermocycling of a block comprising multiple sample |
EP2008717A2 (en) | 2007-06-28 | 2008-12-31 | Sony Corporation | Reaction device with accurate temperature control |
EP2027251A2 (en) * | 2006-05-17 | 2009-02-25 | California Institute of Technology | Thermal cycling system |
EP2060324A1 (en) * | 2007-11-13 | 2009-05-20 | F.Hoffmann-La Roche Ag | Thermal block unit |
EP2123360A1 (en) * | 2008-05-20 | 2009-11-25 | F.Hoffmann-La Roche Ag | Thermocycling device having a thermocycler module with a thermal switch, method of cooling a heating block in a thermocycler module of a thermocycling device and analytical apparatus |
WO2010035063A1 (en) * | 2008-09-23 | 2010-04-01 | Koninklijke Philips Electronics N.V. | Thermocycling device |
WO2011117414A3 (en) * | 2010-03-26 | 2011-11-17 | Micropelt Gmbh | Device for carrying out pcr, method for producing a device for carrying out pcr and pcr method |
EP2563513A1 (en) * | 2010-04-30 | 2013-03-06 | Bigtec Private Limited | A non contact real time micro polymerase chain reaction system and method thereof |
DE102011119174A1 (en) | 2011-11-23 | 2013-05-23 | Inheco Industrial Heating And Cooling Gmbh | Vapor Chamber |
EP2704835A1 (en) * | 2011-05-06 | 2014-03-12 | Bio-Rad Laboratories, Inc. | Thermal cycler with vapor chamber for rapid temperature changes |
CN101585009B (en) * | 2008-05-19 | 2014-07-30 | 霍夫曼-拉罗奇有限公司 | Improved cooler/heater arrangement |
US8828712B2 (en) | 2007-06-29 | 2014-09-09 | Toppan Printing Co., Ltd. | Genetic detection and determination apparatus and method, gene reactor, and incubator |
US8859271B2 (en) | 2003-05-30 | 2014-10-14 | Applied Biosystems, Llc | Thermal cycling apparatus and method for providing thermal uniformity |
EP2898952A1 (en) * | 2006-09-06 | 2015-07-29 | Life Technologies Corporation | Device for Carrying Out Chemical or Biological Reactions |
DE112012002800B4 (en) * | 2011-07-25 | 2015-08-27 | Hitachi High-Technologies Corp. | Nucleic acid test device |
DE112012002529B4 (en) * | 2011-06-24 | 2015-09-10 | Hitachi High-Technologies Corp. | Nucleic acid amplification device and nucleic acid analysis device |
US9316586B2 (en) | 2006-05-17 | 2016-04-19 | California Institute Of Technology | Apparatus for thermal cycling |
WO2018060326A1 (en) * | 2016-09-29 | 2018-04-05 | Qiagen Lake Constance Gmbh | Sample container arrangement |
US10137452B2 (en) | 2010-04-09 | 2018-11-27 | Life Technologies Corporation | Thermal uniformity for thermal cycler instrumentation using dynamic control |
EP2879981B1 (en) * | 2012-07-31 | 2019-03-13 | Gen-Probe Incorporated | System, method, and apparatus for automated incubation |
US10471431B2 (en) | 2014-02-18 | 2019-11-12 | Life Technologies Corporation | Apparatuses, systems and methods for providing scalable thermal cyclers and isolating thermoelectric devices |
US10512915B2 (en) | 2010-05-07 | 2019-12-24 | Hitachi High-Technologies Corporation | Nucleic acid amplifier and nucleic acid inspection device employing the same |
US10527355B2 (en) | 2017-06-13 | 2020-01-07 | Microsoft Technology Licensing, Llc | Devices, methods, and systems for thermal management |
US10835901B2 (en) | 2013-09-16 | 2020-11-17 | Life Technologies Corporation | Apparatuses, systems and methods for providing thermocycler thermal uniformity |
US11279967B2 (en) | 2013-03-14 | 2022-03-22 | Gen-Probe Incorporated | System and method for conducting an assay |
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DE04752947T1 (en) * | 2003-05-23 | 2006-11-16 | Bio-Rad Laboratories, Inc., Hercules | LOCALIZED TEMPERATURE CONTROL FOR ROOM ARRANGEMENTS OF REACTION MEDIA |
JP4695851B2 (en) * | 2003-07-10 | 2011-06-08 | シチズンホールディングス株式会社 | Micro chemical chip temperature controller |
US7622296B2 (en) * | 2004-05-28 | 2009-11-24 | Wafergen, Inc. | Apparatus and method for multiplex analysis |
CN100405625C (en) * | 2005-07-18 | 2008-07-23 | 财团法人工业技术研究院 | Method for integrating biological chip into micro thermoelectric elment and its structure |
CN101341030A (en) * | 2005-12-22 | 2009-01-07 | 皇家飞利浦电子股份有限公司 | Ink jet device for the positioning of a substance onto a substrate, method for the positioning of a substance onto a substrate and use of an ink jet device |
RU2008148143A (en) | 2006-06-08 | 2010-06-10 | Конинклейке Филипс Электроникс Н.В. (Nl) | MICROELECTRONIC SENSOR DEVICE FOR DNA DETECTION |
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Also Published As
Publication number | Publication date |
---|---|
JP2007503217A (en) | 2007-02-22 |
US20100099581A1 (en) | 2010-04-22 |
US7771933B2 (en) | 2010-08-10 |
US20050009070A1 (en) | 2005-01-13 |
EP1641563A2 (en) | 2006-04-05 |
EP1641563A4 (en) | 2012-01-18 |
WO2004105947A3 (en) | 2005-12-22 |
US9623414B2 (en) | 2017-04-18 |
EP1641563B1 (en) | 2018-08-29 |
US20150258547A1 (en) | 2015-09-17 |
DE04752947T1 (en) | 2006-11-16 |
CA2523040A1 (en) | 2004-12-09 |
CA2523040C (en) | 2012-01-17 |
AU2004243070B2 (en) | 2010-04-15 |
JP4705035B2 (en) | 2011-06-22 |
US8945881B2 (en) | 2015-02-03 |
US20170239663A1 (en) | 2017-08-24 |
AU2004243070A1 (en) | 2004-12-09 |
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