WO2004066822A3 - Integrated lancing test strip - Google Patents

Integrated lancing test strip Download PDF

Info

Publication number
WO2004066822A3
WO2004066822A3 PCT/US2004/002476 US2004002476W WO2004066822A3 WO 2004066822 A3 WO2004066822 A3 WO 2004066822A3 US 2004002476 W US2004002476 W US 2004002476W WO 2004066822 A3 WO2004066822 A3 WO 2004066822A3
Authority
WO
WIPO (PCT)
Prior art keywords
incision
lancet
channel
capillary channel
housing
Prior art date
Application number
PCT/US2004/002476
Other languages
French (fr)
Other versions
WO2004066822A2 (en
Inventor
Steven N Roe
Charles C Raney
Volker Zimmer
Jeffrey N Roe
Original Assignee
Roche Diagnostics Gmbh
Hoffmann La Roche
Steven N Roe
Charles C Raney
Volker Zimmer
Jeffrey N Roe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Hoffmann La Roche, Steven N Roe, Charles C Raney, Volker Zimmer, Jeffrey N Roe filed Critical Roche Diagnostics Gmbh
Priority to AT04706470T priority Critical patent/ATE537752T1/en
Priority to EP04706470A priority patent/EP1589873B1/en
Publication of WO2004066822A2 publication Critical patent/WO2004066822A2/en
Publication of WO2004066822A3 publication Critical patent/WO2004066822A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150175—Adjustment of penetration depth
    • A61B5/150198—Depth adjustment mechanism at the proximal end of the carrier of the piercing element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150213—Venting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150358—Strips for collecting blood, e.g. absorbent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150541—Breakable protectors, e.g. caps, shields or sleeves, i.e. protectors separated destructively, e.g. by breaking a connecting area
    • A61B5/150564—Protectors removed by pulling or pushing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150801—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150824—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15142—Devices intended for single use, i.e. disposable
    • A61B5/15144—Devices intended for single use, i.e. disposable comprising driving means, e.g. a spring, for retracting the piercing unit into the housing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase

Abstract

An integrated bodily fluid sampling device (60) is used to sample a bodily fluid from an incision in skin. The device includes a lancet (62) for forming the incision in the skin. A housing is coupled to the lancet (62). The housing defines at least in part a capillary channel (98) with an opening (100). The capillary channel (98) is sized to draw the bodily fluid from the incision via capillary action. A test size (72) is positioned along the capillary channel (98) for analyzing the fluid. In one form, a flexible sheet (76) extends from the housing proximal the opening (100) of the capillary channel (98) for drawing the bodily fluid into the opening (100) of the capillary channel (98). In another form, the lancet (62) is slidably received inside the channel (98). During lancing, the lancet (62) extends from the housing to form the incision. Fluid from the incision is drawn into the channel (98) and is deposited on the test strip (72) for anaylsis.
PCT/US2004/002476 2003-01-29 2004-01-29 Integrated lancing test strip WO2004066822A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT04706470T ATE537752T1 (en) 2003-01-29 2004-01-29 INTEGRATED LANCET TEST STRIP
EP04706470A EP1589873B1 (en) 2003-01-29 2004-01-29 Integrated lancing test strip

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44332803P 2003-01-29 2003-01-29
US60/443,328 2003-01-29

Publications (2)

Publication Number Publication Date
WO2004066822A2 WO2004066822A2 (en) 2004-08-12
WO2004066822A3 true WO2004066822A3 (en) 2004-12-02

Family

ID=32825321

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/002476 WO2004066822A2 (en) 2003-01-29 2004-01-29 Integrated lancing test strip

Country Status (4)

Country Link
US (1) US7374546B2 (en)
EP (1) EP1589873B1 (en)
AT (1) ATE537752T1 (en)
WO (1) WO2004066822A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192375B2 (en) 2012-02-29 2015-11-24 Marker Medical, Llc Surgical apparatus and method

Families Citing this family (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US7310543B2 (en) * 2001-03-26 2007-12-18 Kumetrix, Inc. Silicon microprobe with integrated biosensor
US7476533B2 (en) 2002-04-19 2009-01-13 Adhesives Research, Inc. Diagnostic devices for use in the assaying of biological fluids
ATE485766T1 (en) 2001-06-12 2010-11-15 Pelikan Technologies Inc ELECTRICAL ACTUATING ELEMENT FOR A LANCET
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
DE60234598D1 (en) 2001-06-12 2010-01-14 Pelikan Technologies Inc SELF-OPTIMIZING LANZET DEVICE WITH ADAPTANT FOR TEMPORAL FLUCTUATIONS OF SKIN PROPERTIES
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
EP1404234B1 (en) 2001-06-12 2011-02-09 Pelikan Technologies Inc. Apparatus for improving success rate of blood yield from a fingerstick
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
DE10134650B4 (en) 2001-07-20 2009-12-03 Roche Diagnostics Gmbh System for taking small amounts of body fluid
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8052926B2 (en) * 2002-12-27 2011-11-08 Roche Diagnostics Operations, Inc. Method for manufacturing a sterilized lancet integrated biosensor
US7481777B2 (en) * 2006-01-05 2009-01-27 Roche Diagnostics Operations, Inc. Lancet integrated test element tape dispenser
US7815579B2 (en) * 2005-03-02 2010-10-19 Roche Diagnostics Operations, Inc. Dynamic integrated lancing test strip with sterility cover
US7214200B2 (en) * 2002-12-30 2007-05-08 Roche Diagnostics Operations, Inc. Integrated analytical test element
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7211052B2 (en) * 2002-12-30 2007-05-01 Roche Diagnostics Operations, Inc. Flexible test strip lancet device
US7052652B2 (en) 2003-03-24 2006-05-30 Rosedale Medical, Inc. Analyte concentration detection devices and methods
DE10315544B4 (en) * 2003-04-04 2007-02-15 Roche Diagnostics Gmbh Method for producing a piercing and measuring device and device
EP1628567B1 (en) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Method and apparatus for fluid injection
DK1633235T3 (en) 2003-06-06 2014-08-18 Sanofi Aventis Deutschland Apparatus for sampling body fluid and detecting analyte
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8071030B2 (en) 2003-06-20 2011-12-06 Roche Diagnostics Operations, Inc. Test strip with flared sample receiving chamber
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
ES2657627T3 (en) * 2003-06-20 2018-03-06 F. Hoffmann-La Roche Ag Electrochemical biosensors
PT1639352T (en) 2003-06-20 2018-07-09 Hoffmann La Roche Method and reagent for producing narrow, homogenous reagent strips
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
JP4334969B2 (en) * 2003-10-02 2009-09-30 パナソニック株式会社 Blood component analysis sensor
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc Method and apparatus for a variable user interface
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8394341B2 (en) * 2004-03-08 2013-03-12 Agilent Technologies, Inc. Microfluidic chip frame
WO2005104949A1 (en) * 2004-04-15 2005-11-10 Roche Diagnostics Gmbh Integrated spot monitoring device with fluid sensor
US7322942B2 (en) * 2004-05-07 2008-01-29 Roche Diagnostics Operations, Inc. Integrated disposable for automatic or manual blood dosing
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc Method and apparatus for a fluid sampling device
US7766845B2 (en) * 2004-06-21 2010-08-03 Roche Diagnostics Operations, Inc. Disposable lancet and lancing cap combination for increased hygiene
US20060036187A1 (en) * 2004-06-30 2006-02-16 Hester Vos Devices, systems and methods for extracting bodily fluid and monitoring an analyte therein
US7727166B2 (en) * 2004-07-26 2010-06-01 Nova Biomedical Corporation Lancet, lancet assembly and lancet-sensor combination
GB0420256D0 (en) 2004-09-13 2004-10-13 Cassells John M Method and apparatus for sampling and analysis of fluids
US7488298B2 (en) * 2004-10-08 2009-02-10 Roche Diagnostics Operations, Inc. Integrated lancing test strip with capillary transfer sheet
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US7524671B2 (en) * 2005-01-27 2009-04-28 Prescient Medical, Inc. Handheld raman blood analyzer
US7651851B2 (en) * 2005-01-27 2010-01-26 Prescient Medical, Inc. Handheld Raman body fluid analyzer
US7688440B2 (en) * 2005-01-27 2010-03-30 Prescient Medical, Inc. Raman spectroscopic test strip systems
US7695442B2 (en) * 2005-04-12 2010-04-13 Roche Diagnostics Operations, Inc. Integrated lancing test strip with retractable lancet
US7935063B2 (en) * 2005-03-02 2011-05-03 Roche Diagnostics Operations, Inc. System and method for breaking a sterility seal to engage a lancet
US7955271B2 (en) 2006-10-13 2011-06-07 Roche Diagnostics Operations, Inc. Tape transport lance sampler
WO2006100265A1 (en) * 2005-03-24 2006-09-28 F. Hoffmann-La Roche Ag Analytical aid with a lancet and a testing element
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
US8636672B2 (en) * 2007-02-28 2014-01-28 Nipro Diagnostics, Inc. Test strip with integrated lancet
US20100081968A1 (en) * 2005-07-15 2010-04-01 Home Diagnostics, Inc. Test Strip With Integrated Lancet
US7775991B2 (en) * 2005-08-31 2010-08-17 Kimberly-Clark Worldwide, Inc. Device for sampling blood
EP1759633A1 (en) 2005-09-01 2007-03-07 F.Hoffmann-La Roche Ag Device for sampling bodily fluids and its fabrication method
US8801631B2 (en) * 2005-09-30 2014-08-12 Intuity Medical, Inc. Devices and methods for facilitating fluid transport
EP1928304B1 (en) 2005-09-30 2012-10-24 Intuity Medical, Inc. Catalysts for body fluid sample extraction
US8057404B2 (en) * 2005-10-12 2011-11-15 Panasonic Corporation Blood sensor, blood testing apparatus, and method for controlling blood testing apparatus
EP1785090A1 (en) * 2005-11-10 2007-05-16 F.Hoffmann-La Roche Ag Lancet device and system for skin detection
WO2007057704A1 (en) * 2005-11-21 2007-05-24 Inverness Medical Switzerland Gmbh Test device
WO2007092173A2 (en) * 2006-02-06 2007-08-16 Prescient Medical, Inc. Raman spectroscopic lateral flow test strip assays
EP1818014A1 (en) 2006-02-09 2007-08-15 F. Hoffmann-la Roche AG Test element with elastically supported lancet
JP4953139B2 (en) * 2006-04-17 2012-06-13 住友電気工業株式会社 Biosensor chip
ATE490199T1 (en) * 2006-06-23 2010-12-15 Hoffmann La Roche PACKAGING SYSTEM
GB0617035D0 (en) * 2006-08-30 2006-10-11 Inverness Medical Switzerland Fluidic indicator device
EP1894526A1 (en) * 2006-09-04 2008-03-05 F. Hoffmann-la Roche AG Lancet
US8852124B2 (en) 2006-10-13 2014-10-07 Roche Diagnostics Operations, Inc. Tape transport lance sampler
US8052618B2 (en) * 2006-10-15 2011-11-08 Roche Diagnostics Operations, Inc. Diagnostic test element and process for its production
US20100069792A1 (en) * 2006-11-10 2010-03-18 National Institute Of Advanced Industrial Science And Technology Biosensor cartridge, biosensor device, sample collecting method, manufacturing method of biosensor cartridge, and needle integral sensor
US7802467B2 (en) * 2006-12-22 2010-09-28 Abbott Diabetes Care Inc. Analyte sensors and methods of use
JP2008167942A (en) * 2007-01-11 2008-07-24 National Institute Of Advanced Industrial & Technology Biosensor cartridge
WO2008105373A1 (en) * 2007-02-26 2008-09-04 National Institute Of Advanced Industrial Science And Technology Sensor device
WO2009008193A1 (en) * 2007-07-11 2009-01-15 Nitto Denko Corporation Body fluid collecting circuit board
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
WO2009145920A1 (en) 2008-05-30 2009-12-03 Intuity Medical, Inc. Body fluid sampling device -- sampling site interface
EP2299904B1 (en) 2008-06-06 2019-09-11 Intuity Medical, Inc. Medical measurement method
US9636051B2 (en) 2008-06-06 2017-05-02 Intuity Medical, Inc. Detection meter and mode of operation
EP2316339A4 (en) * 2008-08-01 2012-10-24 Lightnix Inc Sensor with fine needle having channel formed therein
CN102227636A (en) * 2008-09-30 2011-10-26 梅纳伊医疗科技有限公司 Sample measurement system
AU2010209763B2 (en) 2009-01-30 2016-05-12 Mycartis N.V. Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US20110040208A1 (en) * 2009-08-11 2011-02-17 Abbott Diabetes Care Inc. Integrated lancet and test strip and methods of making and using same
NO2491401T3 (en) 2009-10-21 2018-11-03
EP3106871B1 (en) 2009-11-30 2021-10-27 Intuity Medical, Inc. A method of verifying the accuracy of the operation of an analyte monitoring device
CA2788760A1 (en) 2010-03-26 2011-09-29 Pronota N.V. Ltbp2 as a biomarker for renal dysfunction
GB201005359D0 (en) 2010-03-30 2010-05-12 Menai Medical Technologies Ltd Sampling plate
GB201005357D0 (en) 2010-03-30 2010-05-12 Menai Medical Technologies Ltd Sampling plate
JP2013524251A (en) 2010-04-13 2013-06-17 プロノタ エヌ．ヴェ． Biomarkers for pregnancy-induced hypertension
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
CA2803797A1 (en) 2010-06-25 2011-12-29 Intuity Medical, Inc. Analyte monitoring methods and systems
EP3407064B1 (en) 2011-08-03 2020-04-22 Intuity Medical, Inc. Body fluid sampling arrangement
US10729386B2 (en) 2013-06-21 2020-08-04 Intuity Medical, Inc. Analyte monitoring system with audible feedback
TWI568417B (en) * 2014-12-01 2017-02-01 國竤工業有限公司 Biochemical reaction cartridge
US10154809B2 (en) 2015-06-24 2018-12-18 University Of Virginia Patent Foundation Test strip device and related methods thereof
EP4289356A3 (en) 2015-09-09 2024-02-28 Drawbridge Health, Inc. Devices for sample collection, stabilization and preservation
EP3568076A4 (en) 2017-01-10 2020-10-21 Drawbridge Health, Inc. Devices, systems, and methods for sample collection
USD849265S1 (en) * 2017-04-21 2019-05-21 Precision Nanosystems Inc Microfluidic chip

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0582276A1 (en) * 1992-08-03 1994-02-09 United States Surgical Corporation Needles made from non-round stock
US5529581A (en) * 1994-05-17 1996-06-25 International Technidyne Corporation Lancet device for creating a skin incision
DE19753847A1 (en) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytical test element with capillary channel
CA2287757A1 (en) * 1999-10-29 2001-04-29 Medical Plastic Devices M.P.D. Inc. Disposable lancet
US20020004196A1 (en) * 2000-07-10 2002-01-10 Bayer Corporation Thin lance and test sensor having same
WO2002026129A1 (en) * 2000-09-28 2002-04-04 Norwood Abbey Ltd Diagnostic device
WO2002056751A2 (en) * 2001-01-22 2002-07-25 Roche Diagnostics Gmbh Lancet device having capillary action
US20020177761A1 (en) * 2001-04-26 2002-11-28 Phoenix Bioscience Integrated lancing and analytic device

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1328459A (en) * 1918-10-18 1920-01-20 Arthur E Smith Instrument for producing intra-osseous anesthesia
US2359550A (en) * 1942-07-07 1944-10-03 Salsbury S Lab Dr Fowl vaccinator
US2646799A (en) * 1951-02-14 1953-07-28 Jr George W Jacoby Blood lancet
US2801633A (en) * 1954-02-17 1957-08-06 Joseph C Ehrlich Lancets
DE2118455B1 (en) * 1971-04-16 1972-09-21 Boehringer Mannheim Gmbh Test strips
DE2436598C2 (en) * 1974-07-30 1983-04-07 Boehringer Mannheim Gmbh, 6800 Mannheim Stable test strip for the detection of ingredients in liquids
US4095589A (en) * 1975-05-20 1978-06-20 Plastronics, Inc. Combination urine meter and drainage receptacle
DE2642896C3 (en) * 1976-09-24 1980-08-21 7800 Freiburg Precision snapper for setting standard stab wounds in the skin for diagnostic purposes
USD254444S (en) * 1977-09-01 1980-03-11 Levine Robert A Blood sampling needle
US4360016A (en) * 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4375815A (en) * 1981-03-23 1983-03-08 Becton Dickinson And Company Retractable lancet assembly
FR2508305B1 (en) * 1981-06-25 1986-04-11 Slama Gerard DEVICE FOR CAUSING A LITTLE BITE TO COLLECT A BLOOD DROP
DE3211167A1 (en) * 1982-03-26 1983-09-29 Merck Patent Gmbh, 6100 Darmstadt TEST SYSTEM AND METHOD FOR DETERMINING SUBSTANCES IN LIQUIDS
US4462405A (en) * 1982-09-27 1984-07-31 Ehrlich Joseph C Blood letting apparatus
US4616649A (en) * 1984-09-20 1986-10-14 Becton, Dickinson And Company Lancet
US4787398A (en) * 1985-04-08 1988-11-29 Garid, Inc. Glucose medical monitoring system
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US4653513A (en) * 1985-08-09 1987-03-31 Dombrowski Mitchell P Blood sampler
GB8710470D0 (en) * 1987-05-01 1987-06-03 Mumford Ltd Owen Blood sampling devices
US4924879A (en) * 1988-10-07 1990-05-15 Brien Walter J O Blood lancet device
US4895147A (en) * 1988-10-28 1990-01-23 Sherwood Medical Company Lancet injector
US4990154A (en) * 1989-06-19 1991-02-05 Miles Inc. Lancet assembly
US5100391A (en) * 1990-04-03 1992-03-31 Schutte Michael J Double-bladed scalpel
US5607437A (en) * 1990-07-12 1997-03-04 University Of Miami Instruments for use in performing gel injection adjustable keratoplasty
US5607401A (en) * 1991-09-03 1997-03-04 Humphrey; Bruce H. Augmented polymeric hypodermic devices
WO1993009723A1 (en) * 1991-11-12 1993-05-27 Ramel Urs A Lancet device
DE4212315A1 (en) * 1992-04-13 1993-10-14 Boehringer Mannheim Gmbh Blood lancet device for drawing blood for diagnostic purposes
CA2079192C (en) * 1992-09-25 1995-12-26 Bernard Strong Combined lancet and multi-function cap and lancet injector for use therewith
DE4318142C2 (en) * 1993-06-02 1995-07-06 Richard Herbst Lancet device for preparing a blood sample
US5304193A (en) * 1993-08-12 1994-04-19 Sam Zhadanov Blood lancing device
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5628765A (en) * 1994-11-29 1997-05-13 Apls Co., Ltd. Lancet assembly
US5628764A (en) * 1995-03-21 1997-05-13 Schraga; Steven Collar lancet device
JP3638958B2 (en) * 1995-07-28 2005-04-13 アプルス株式会社 Assembly for adjusting the penetration depth of the lancet
DE19604156A1 (en) * 1996-02-06 1997-08-07 Boehringer Mannheim Gmbh Skin cutting device for taking pain-free small amounts of blood
US5962215A (en) * 1996-04-05 1999-10-05 Mercury Diagnostics, Inc. Methods for testing the concentration of an analyte in a body fluid
US5776719A (en) * 1997-07-07 1998-07-07 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
US5857983A (en) * 1996-05-17 1999-01-12 Mercury Diagnostics, Inc. Methods and apparatus for sampling body fluid
US5951492A (en) * 1996-05-17 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for sampling and analyzing body fluid
US5951493A (en) * 1997-05-16 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for expressing body fluid from an incision
EP0906062B1 (en) * 1996-05-17 2007-12-26 Roche Diagnostics Operations, Inc. Body fluid sampling device
US5879311A (en) 1996-05-17 1999-03-09 Mercury Diagnostics, Inc. Body fluid sampling device and methods of use
US6332871B1 (en) * 1996-05-17 2001-12-25 Amira Medical Blood and interstitial fluid sampling device
EP1579814A3 (en) * 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US5824491A (en) * 1996-05-17 1998-10-20 Mercury Diagnostics, Inc. Dry reagent test strip comprising benzidine dye precursor and antipyrine compound
US5613978A (en) * 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
US5830225A (en) * 1996-08-19 1998-11-03 Detsch; Steven G. Dental and medical tissue knife
US5873887A (en) * 1996-10-25 1999-02-23 Bayer Corporation Blood sampling device
US6045497A (en) * 1997-01-02 2000-04-04 Myocor, Inc. Heart wall tension reduction apparatus and method
DE69809391T2 (en) * 1997-02-06 2003-07-10 Therasense Inc SMALL VOLUME SENSOR FOR IN-VITRO DETERMINATION
US5798031A (en) * 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US5984940A (en) * 1997-05-29 1999-11-16 Atrion Medical Products, Inc. Lancet device
US5916230A (en) * 1997-06-16 1999-06-29 Bayer Corporation Blood sampling device with adjustable end cap
FI111217B (en) 1997-06-19 2003-06-30 Nokia Corp Apparatus for sampling
JP3123474B2 (en) * 1997-07-28 2001-01-09 トヨタ自動車株式会社 Exhaust gas purification device for internal combustion engine
US5964718A (en) * 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
US6071294A (en) * 1997-12-04 2000-06-06 Agilent Technologies, Inc. Lancet cartridge for sampling blood
US6036924A (en) * 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US5971941A (en) * 1997-12-04 1999-10-26 Hewlett-Packard Company Integrated system and method for sampling blood and analysis
US5871494A (en) * 1997-12-04 1999-02-16 Hewlett-Packard Company Reproducible lancing for sampling blood
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
JP3902875B2 (en) 1998-10-19 2007-04-11 テルモ株式会社 Puncture device
US6086545A (en) * 1998-04-28 2000-07-11 Amira Medical Methods and apparatus for suctioning and pumping body fluid from an incision
US6346114B1 (en) * 1998-06-11 2002-02-12 Stat Medical Devices, Inc. Adjustable length member such as a cap of a lancet device for adjusting penetration depth
US6022366A (en) * 1998-06-11 2000-02-08 Stat Medical Devices Inc. Lancet having adjustable penetration depth
DE19844500A1 (en) * 1998-09-29 2000-03-30 Roche Diagnostics Gmbh Process for the photometric evaluation of test elements
ATE408372T1 (en) * 1999-01-04 2008-10-15 Terumo Corp LANDZET ARRANGEMENT FOR COLLECTION AND DETECTION OF BODY FLUID
US6045567A (en) * 1999-02-23 2000-04-04 Lifescan Inc. Lancing device causing reduced pain
DE19909602A1 (en) * 1999-03-05 2000-09-07 Roche Diagnostics Gmbh Device for drawing blood for diagnostic purposes
US6306152B1 (en) * 1999-03-08 2001-10-23 Agilent Technologies, Inc. Lancet device with skin movement control and ballistic preload
US6132449A (en) * 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
DE19948759A1 (en) * 1999-10-09 2001-04-12 Roche Diagnostics Gmbh Blood lancet device for drawing blood for diagnostic purposes
US6283982B1 (en) * 1999-10-19 2001-09-04 Facet Technologies, Inc. Lancing device and method of sample collection
US6620112B2 (en) * 2000-03-24 2003-09-16 Novo Nordisk A/S Disposable lancet combined with a reagent carrying strip and a system for extracting and analyzing blood in the body utilizing such a disposable lancet
US6612111B1 (en) * 2000-03-27 2003-09-02 Lifescan, Inc. Method and device for sampling and analyzing interstitial fluid and whole blood samples
PL191428B1 (en) * 2000-04-06 2006-05-31 Htl Strefa Sp Z Oo Puncturing depth adjusting assembly for puncturing devices
DE10030410C1 (en) * 2000-06-21 2002-01-24 Roche Diagnostics Gmbh Blood lancet device for drawing blood for diagnostic purposes
US6806093B2 (en) * 2000-07-18 2004-10-19 Uop Llc Process of parallel sample preparation
TW495353B (en) 2000-09-01 2002-07-21 Bayer Ag Adjustable endcap for lancing device
KR100708101B1 (en) * 2000-09-05 2007-04-16 삼성전자주식회사 Envelope detecting circuit layout design method of video signal processing IC and IC using thereof
US6800488B2 (en) * 2000-12-13 2004-10-05 Lifescan, Inc. Methods of manufacturing reagent test strips
US20020177763A1 (en) * 2001-05-22 2002-11-28 Burns David W. Integrated lancets and methods
US20030028087A1 (en) 2001-08-01 2003-02-06 Yuzhakov Vadim Vladimirovich Devices for analyte concentration determination and methods of using the same

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0582276A1 (en) * 1992-08-03 1994-02-09 United States Surgical Corporation Needles made from non-round stock
US5529581A (en) * 1994-05-17 1996-06-25 International Technidyne Corporation Lancet device for creating a skin incision
DE19753847A1 (en) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytical test element with capillary channel
CA2287757A1 (en) * 1999-10-29 2001-04-29 Medical Plastic Devices M.P.D. Inc. Disposable lancet
US20020004196A1 (en) * 2000-07-10 2002-01-10 Bayer Corporation Thin lance and test sensor having same
WO2002026129A1 (en) * 2000-09-28 2002-04-04 Norwood Abbey Ltd Diagnostic device
WO2002056751A2 (en) * 2001-01-22 2002-07-25 Roche Diagnostics Gmbh Lancet device having capillary action
US20020177761A1 (en) * 2001-04-26 2002-11-28 Phoenix Bioscience Integrated lancing and analytic device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192375B2 (en) 2012-02-29 2015-11-24 Marker Medical, Llc Surgical apparatus and method
US9572566B2 (en) 2012-02-29 2017-02-21 Marker Medical, Llc Surgical suturing apparatus and method

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US20040186394A1 (en) 2004-09-23
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