WO2004061418A3 - Assay cartridges and methods of using the same - Google Patents
Assay cartridges and methods of using the same Download PDFInfo
- Publication number
- WO2004061418A3 WO2004061418A3 PCT/US2003/041241 US0341241W WO2004061418A3 WO 2004061418 A3 WO2004061418 A3 WO 2004061418A3 US 0341241 W US0341241 W US 0341241W WO 2004061418 A3 WO2004061418 A3 WO 2004061418A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- modules
- assay
- chambers
- cartridges
- methods
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0017—Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/0074—Biological products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2511389A CA2511389C (en) | 2002-12-26 | 2003-12-23 | Assay cartridges and methods of using the same |
JP2004565694A JP4764010B2 (en) | 2002-12-26 | 2003-12-23 | Assay cartridge and method using the same |
EP03810079.8A EP1583950B1 (en) | 2002-12-26 | 2003-12-23 | Assay cartridges and methods of using the same |
CN2003801099993A CN101098956B (en) | 2002-12-26 | 2003-12-23 | Assay cartridges and methods of using the same |
EP13198399.1A EP2711415B1 (en) | 2002-12-26 | 2003-12-23 | Assay cartridges and methods of using the same |
AU2003302263A AU2003302263A1 (en) | 2002-12-26 | 2003-12-23 | Assay cartridges and methods of using the same |
HK08107106.8A HK1117189A1 (en) | 2002-12-26 | 2008-06-26 | Assay cartridges and methods of using the same |
AU2011200010A AU2011200010B2 (en) | 2002-12-26 | 2011-01-04 | Assay cartridges and methods of using the same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43656902P | 2002-12-26 | 2002-12-26 | |
US60/436,569 | 2002-12-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004061418A2 WO2004061418A2 (en) | 2004-07-22 |
WO2004061418A3 true WO2004061418A3 (en) | 2007-09-07 |
Family
ID=32713071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/041241 WO2004061418A2 (en) | 2002-12-26 | 2003-12-23 | Assay cartridges and methods of using the same |
Country Status (8)
Country | Link |
---|---|
US (10) | US7497997B2 (en) |
EP (2) | EP1583950B1 (en) |
JP (4) | JP4764010B2 (en) |
CN (2) | CN101098956B (en) |
AU (2) | AU2003302263A1 (en) |
CA (5) | CA2772050C (en) |
HK (1) | HK1117189A1 (en) |
WO (1) | WO2004061418A2 (en) |
Families Citing this family (493)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
US8383043B2 (en) * | 2004-05-14 | 2013-02-26 | Honeywell International Inc. | Analyzer system |
US8071051B2 (en) | 2004-05-14 | 2011-12-06 | Honeywell International Inc. | Portable sample analyzer cartridge |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
DE10162064A1 (en) * | 2001-12-17 | 2003-06-26 | Sunyx Surface Nanotechnologies | Hydrophobic surface for storage, analysis and handling of minute droplets, is populated with sub-surface electrodes producing electrical fields |
US20070166725A1 (en) * | 2006-01-18 | 2007-07-19 | The Regents Of The University Of California | Multiplexed diagnostic platform for point-of care pathogen detection |
US20040152211A1 (en) * | 2002-11-15 | 2004-08-05 | The Regents Of The University Of California | System and method for multiplexed biomolecular analysis |
CA2772050C (en) | 2002-12-26 | 2016-09-06 | Meso Scale Technologies, Llc. | Assay cartridges and methods of using the same |
EP1604183B1 (en) * | 2002-12-26 | 2012-08-29 | Meso Scale Technologies, LLC. | Methods for biomarker extraction |
EP1603674B1 (en) | 2003-02-05 | 2016-01-06 | Iquum, Inc. | Sample processing |
SE0300823D0 (en) | 2003-03-23 | 2003-03-23 | Gyros Ab | Preloaded Microscale Devices |
US7994877B1 (en) | 2008-11-10 | 2011-08-09 | Hrl Laboratories, Llc | MEMS-based quartz hybrid filters and a method of making the same |
US8766745B1 (en) | 2007-07-25 | 2014-07-01 | Hrl Laboratories, Llc | Quartz-based disk resonator gyro with ultra-thin conductive outer electrodes and method of making same |
AU2004273783A1 (en) | 2003-07-12 | 2005-03-31 | Accelr8 Technology Corporation | Sensitive and rapid biodetection |
US7341841B2 (en) * | 2003-07-12 | 2008-03-11 | Accelr8 Technology Corporation | Rapid microbial detection and antimicrobial susceptibility testing |
US20120077206A1 (en) * | 2003-07-12 | 2012-03-29 | Accelr8 Technology Corporation | Rapid Microbial Detection and Antimicrobial Susceptibility Testing |
EP2402089A1 (en) | 2003-07-31 | 2012-01-04 | Handylab, Inc. | Processing particle-containing samples |
EP1508792B1 (en) * | 2003-08-19 | 2012-11-28 | Kurashiki Boseki Kabushiki Kaisha | Extracting apparatus |
FR2860006B1 (en) * | 2003-09-24 | 2006-12-22 | Commissariat Energie Atomique | DEVICE FOR SEPARATING AND / OR ANALYZING MULTIPLE MOLECULAR TARGETS IN SOLUTION IN A COMPLEX MIXTURE |
KR101001549B1 (en) * | 2003-11-20 | 2010-12-17 | 삼성모바일디스플레이주식회사 | Electroluminescence device |
JP4632400B2 (en) * | 2003-12-16 | 2011-02-16 | キヤノン株式会社 | Cell culture substrate, method for producing the same, and cell screening method using the same |
US20090010819A1 (en) * | 2004-01-17 | 2009-01-08 | Gyros Patent Ab | Versatile flow path |
WO2006075966A1 (en) * | 2005-01-17 | 2006-07-20 | Gyros Patent Ab | A versatile flow path |
US8592219B2 (en) * | 2005-01-17 | 2013-11-26 | Gyros Patent Ab | Protecting agent |
GB2416030B (en) * | 2004-01-28 | 2008-07-23 | Norchip As | A diagnostic system for carrying out a nucleic acid sequence amplification and detection process |
US20050227222A1 (en) * | 2004-04-09 | 2005-10-13 | Massachusetts Institute Of Technology | Pathogen identification method |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
ES2553097T3 (en) | 2004-05-03 | 2015-12-04 | Handylab, Inc. | Processing of samples containing polynucleotides |
US8828320B2 (en) * | 2004-05-14 | 2014-09-09 | Honeywell International Inc. | Portable sample analyzer cartridge |
ATE428931T1 (en) | 2004-06-03 | 2009-05-15 | Meso Scale Technologies Llc | METHOD FOR PERFORMING WHOLE BLOOD TESTS |
FI20040825A0 (en) * | 2004-06-15 | 2004-06-15 | Ani Biotech Oy | Filter device, its use, method and kit |
US8097225B2 (en) * | 2004-07-28 | 2012-01-17 | Honeywell International Inc. | Microfluidic cartridge with reservoirs for increased shelf life of installed reagents |
JP2006098169A (en) * | 2004-09-29 | 2006-04-13 | Fujitsu Ltd | Device and method for quantitatively determining analyte |
GB0423961D0 (en) * | 2004-10-28 | 2004-12-01 | Cole Polytechnique Federale De | Adsorption monitoring device |
JP5021486B2 (en) * | 2004-11-10 | 2012-09-05 | ユィロス・パテント・アクチボラグ | Liquid detection and reliability determination |
JPWO2006057225A1 (en) * | 2004-11-25 | 2008-06-05 | 松下電器産業株式会社 | Sensor device |
GB0426082D0 (en) * | 2004-11-26 | 2004-12-29 | Norchip As | A device for carrying out biological assays |
KR100612880B1 (en) * | 2004-12-06 | 2006-08-14 | 삼성전자주식회사 | Packing device for the sample loading hole of a chamber |
US20060205012A1 (en) * | 2004-12-09 | 2006-09-14 | Meso Scale Technologies, Llc | Diagnostic test |
ES2624685T3 (en) * | 2004-12-16 | 2017-07-17 | Accelerate Diagnostics, Inc. | Rapid microbial detection and antimicrobial susceptibility test |
CN101031802B (en) * | 2005-01-07 | 2012-11-07 | 积水化学工业株式会社 | Detection device using cartridge |
JP2008527371A (en) | 2005-01-17 | 2008-07-24 | ユィロス・パテント・アクチボラグ | Method for co-transporting reactants with amphiphilic polymeric materials in microfluidic transport conduits |
US20060183216A1 (en) * | 2005-01-21 | 2006-08-17 | Kalyan Handique | Containers for liquid storage and delivery with application to microfluidic devices |
US20080069729A1 (en) * | 2005-02-16 | 2008-03-20 | Mcneely Michael R | Liquid Valving Using Reactive or Responsive Materials |
DE102005012567B4 (en) * | 2005-03-04 | 2008-09-04 | Identif Gmbh | Marking solution, its use and process for its preparation |
US20090068638A1 (en) * | 2005-03-17 | 2009-03-12 | Biophage Inc. | Phage-based method for the detection of bacteria |
JP4548174B2 (en) | 2005-03-24 | 2010-09-22 | コニカミノルタエムジー株式会社 | Microchip for inspection and inspection apparatus using the same |
GB0506710D0 (en) * | 2005-04-01 | 2005-05-11 | Akubio Ltd | Cartridge for a fluid sample analyser |
US8206650B2 (en) * | 2005-04-12 | 2012-06-26 | Chromedx Inc. | Joint-diagnostic spectroscopic and biosensor meter |
US20060233667A1 (en) * | 2005-04-19 | 2006-10-19 | Chromedx Inc. | Joint-diagnostic spectroscopic and biosensor apparatus |
CA2517299A1 (en) * | 2005-08-26 | 2007-02-26 | Chromedx Inc. | Hollow needle assembly |
US20060228258A1 (en) * | 2005-04-12 | 2006-10-12 | Chromedx Inc. | Blood collection and measurement apparatus |
US20100245803A1 (en) * | 2005-04-12 | 2010-09-30 | Chromedx Inc. | Blood sample holder for spectroscopic analysis |
US7740804B2 (en) * | 2005-04-12 | 2010-06-22 | Chromedx Inc. | Spectroscopic sample holder |
CA2507323A1 (en) * | 2005-05-13 | 2006-11-13 | Chromedx Inc. | Diagnostic whole blood and plasma apparatus |
US7713392B2 (en) * | 2005-04-15 | 2010-05-11 | Agamatrix, Inc. | Test strip coding and quality measurement |
US20060264779A1 (en) | 2005-05-09 | 2006-11-23 | Kemp Timothy M | Fluidic medical devices and uses thereof |
US10816563B2 (en) | 2005-05-25 | 2020-10-27 | Boehringer Ingelheim Vetmedica Gmbh | System for operating a system for the integrated and automated analysis of DNA or protein |
EP1883474B1 (en) * | 2005-05-25 | 2021-03-31 | Boehringer Ingelheim Vetmedica GmbH | System for the integrated and automated analysis of dna or protein and method for operating said type of system |
CA2610875A1 (en) * | 2005-06-06 | 2006-12-14 | Decision Biomarkers, Inc. | Assays based on liquid flow over arrays |
US20070031283A1 (en) * | 2005-06-23 | 2007-02-08 | Davis Charles Q | Assay cartridges and methods for point of care instruments |
DE102005029809B4 (en) * | 2005-06-27 | 2007-04-26 | Siemens Ag | Apparatus and method for preparing a sample for analysis and apparatus and method for analyzing a sample |
US8034296B2 (en) * | 2005-07-01 | 2011-10-11 | Honeywell International Inc. | Microfluidic card for RBC analysis |
JP2007017169A (en) * | 2005-07-05 | 2007-01-25 | Yamaha Corp | Biosensor, component detector and stress measuring method of human being |
JP4721414B2 (en) * | 2005-08-15 | 2011-07-13 | キヤノン株式会社 | REACTION CARTRIDGE, REACTOR, AND METHOD FOR TRANSFERRING REACTION CARTRIDGE SOLUTION |
US9913985B2 (en) * | 2006-04-28 | 2018-03-13 | Second Sight Medical Products, Inc. | Method and apparatus to provide safety checks for neural stimulation |
US20070107780A1 (en) * | 2005-11-07 | 2007-05-17 | Bristol-Myers Squibb Company | Fluid handling device |
DE102005054924B4 (en) | 2005-11-17 | 2012-06-14 | Siemens Ag | Apparatus and method for extracting a swab sample |
EP1790861A1 (en) * | 2005-11-25 | 2007-05-30 | Bonsens AB | Microfluidic system |
JP4685611B2 (en) * | 2005-12-02 | 2011-05-18 | 株式会社エンプラス | Microfluidic device |
AU2011265549B2 (en) * | 2005-12-21 | 2013-04-18 | Meso Scale Technologies, Llc | Assay Modules Having Assay Reagents and Methods of Making and Using Same |
CA2634130C (en) | 2005-12-21 | 2021-08-03 | Meso Scale Technologies, Llc | Assay apparatuses, methods and reagents |
CA3179247A1 (en) * | 2005-12-21 | 2007-07-05 | Meso Scale Technologies, Llc | Assay modules having assay reagents and methods of making and using same |
JP5175213B2 (en) * | 2005-12-22 | 2013-04-03 | ハネウェル・インターナショナル・インコーポレーテッド | Portable sample analysis system |
US20070248971A1 (en) * | 2006-01-26 | 2007-10-25 | California Institute Of Technology | Programming microfluidic devices with molecular information |
US20080003564A1 (en) * | 2006-02-14 | 2008-01-03 | Iquum, Inc. | Sample processing |
US20070228721A1 (en) * | 2006-02-15 | 2007-10-04 | Michael Laposata | Systems and devices for assessment and treatment of a myocardial ischemic event |
DE202006020469U1 (en) * | 2006-03-06 | 2008-10-16 | Directif Gmbh | Device for detecting biochemical target molecules |
JP2007240425A (en) * | 2006-03-10 | 2007-09-20 | Kyushu Institute Of Technology | Electrochemical antigen detection method and device for same and detection chip |
AU2007225103A1 (en) * | 2006-03-14 | 2007-09-20 | Perkinelmer Health Sciences, Inc. | System and method for diagnosis of infectious diseases |
JP2007248396A (en) * | 2006-03-17 | 2007-09-27 | Toshiba Corp | Device for detecting nucleic acid, and nucleic acid detector |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8741230B2 (en) | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
EP2001990B1 (en) | 2006-03-24 | 2016-06-29 | Handylab, Inc. | Integrated system for processing microfluidic samples, and method of using same |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US8088616B2 (en) | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
JP4664846B2 (en) | 2006-03-29 | 2011-04-06 | 株式会社東芝 | Nucleic acid detection device |
US7939021B2 (en) * | 2007-05-09 | 2011-05-10 | Advanced Liquid Logic, Inc. | Droplet actuator analyzer with cartridge |
BRPI0711844A2 (en) * | 2006-05-16 | 2011-12-13 | Koninkl Philips Electronics Nv | method and system for determining sample matrix effects, and disposable cartridge |
US20100240022A1 (en) * | 2006-06-23 | 2010-09-23 | Mcneely Michael R | Reagent preparation and valving design for liquid testing |
WO2008002502A2 (en) | 2006-06-23 | 2008-01-03 | Illumina, Inc. | Devices and systems for creation of dna cluster arrays |
AU2007265628B2 (en) * | 2006-06-23 | 2012-12-06 | Perkinelmer Health Sciences, Inc. | Methods and devices for microfluidic point-of-care immunoassays |
DE102006030068A1 (en) * | 2006-06-28 | 2008-01-03 | M2P-Labs Gmbh | Apparatus and method for the supply and removal of fluids in shaken microreactors arrays |
US7555824B2 (en) | 2006-08-09 | 2009-07-07 | Hrl Laboratories, Llc | Method for large scale integration of quartz-based devices |
WO2008030433A2 (en) * | 2006-09-06 | 2008-03-13 | Canon U.S. Life Sciences, Inc. | Chip and cartridge design configuration for performing micro-fluidic assays |
US20100096276A1 (en) * | 2006-10-05 | 2010-04-22 | Panasonic Corporation | Multicomponent analysis sensor and method of measuring multiple components |
US8012744B2 (en) * | 2006-10-13 | 2011-09-06 | Theranos, Inc. | Reducing optical interference in a fluidic device |
WO2008061165A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic cartridge and method of making same |
GB0624582D0 (en) * | 2006-12-08 | 2007-01-17 | Visible Computing Ltd | USB autorun devices |
ATE472110T1 (en) * | 2007-01-12 | 2010-07-15 | Koninkl Philips Electronics Nv | SENSOR DEVICE AND METHOD FOR DETECTING MAGNETIC PARTICLES |
GB2445738A (en) * | 2007-01-16 | 2008-07-23 | Lab901 Ltd | Microfluidic device |
NL1033365C2 (en) * | 2007-02-09 | 2008-08-12 | Medavinci Dev B V | Device and method for separating and analyzing blood. |
WO2008101196A1 (en) * | 2007-02-15 | 2008-08-21 | Osmetech Molecular Diagnostics | Fluidics devices |
JP5553615B2 (en) * | 2007-03-01 | 2014-07-16 | アボット・ラボラトリーズ | Immunoassay showing reduced prozone phenomenon |
US8506908B2 (en) * | 2007-03-09 | 2013-08-13 | Vantix Holdings Limited | Electrochemical detection system |
WO2008112635A1 (en) * | 2007-03-09 | 2008-09-18 | Dxtech, Llc | Multi-channel lock-in amplifier system and method |
EP2142314A4 (en) * | 2007-03-30 | 2012-04-25 | Fujifilm Corp | Method of cleaning micro-flow passages |
US8202492B2 (en) | 2007-05-04 | 2012-06-19 | Opko Diagnostics, Llc | Fluidic connectors and microfluidic systems |
JP5170239B2 (en) * | 2007-05-15 | 2013-03-27 | 和光純薬工業株式会社 | Pressure manifold for equalizing pressure in an integrated PCR-CE microfluidic device |
US20080297169A1 (en) * | 2007-05-31 | 2008-12-04 | Greenquist Alfred C | Particle Fraction Determination of A Sample |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
WO2009012185A1 (en) | 2007-07-13 | 2009-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
US10266398B1 (en) | 2007-07-25 | 2019-04-23 | Hrl Laboratories, Llc | ALD metal coatings for high Q MEMS structures |
EP2020601B1 (en) * | 2007-08-03 | 2010-11-17 | Micronas GmbH | Kit and device for creating chemo luminescent radiation |
US8206025B2 (en) * | 2007-08-07 | 2012-06-26 | International Business Machines Corporation | Microfluid mixer, methods of use and methods of manufacture thereof |
US8470266B2 (en) * | 2007-09-10 | 2013-06-25 | Nec Corporation | Sample packing device |
US8053198B2 (en) * | 2007-09-14 | 2011-11-08 | Meso Scale Technologies, Llc | Diagnostic methods |
CN104502579B (en) | 2007-10-02 | 2018-04-13 | 赛拉诺斯知识产权有限责任公司 | Modular point-of-care devices and its application |
ATE517339T1 (en) * | 2007-11-13 | 2011-08-15 | Hoffmann La Roche | INTERCHANGEABLE CONSUMABLES CASSETTE WITH INTEGRATED AIR FILTER FOR ANALYZERS |
BRPI0819296A2 (en) * | 2007-11-22 | 2015-05-12 | Koninkl Philips Electronics Nv | Sensor Cartridge, Sensor, Methods for Manufacturing a Sensor Cartridge and Determining Target Fractions in a Fluid Sample, Using a Sensor Cartridge, Disposable Device, and Reader Device |
WO2009108260A2 (en) * | 2008-01-22 | 2009-09-03 | Microchip Biotechnologies, Inc. | Universal sample preparation system and use in an integrated analysis system |
US8151640B1 (en) | 2008-02-05 | 2012-04-10 | Hrl Laboratories, Llc | MEMS on-chip inertial navigation system with error correction |
US7802356B1 (en) | 2008-02-21 | 2010-09-28 | Hrl Laboratories, Llc | Method of fabricating an ultra thin quartz resonator component |
JP2009243965A (en) * | 2008-03-28 | 2009-10-22 | Sumitomo Bakelite Co Ltd | Flow path device, flow path device with exterior case, method for using flow path device |
JP2011518323A (en) | 2008-04-11 | 2011-06-23 | メソ スケール テクノロジーズ エルエルシー | Assay devices, methods, and reagents |
NL2001577C2 (en) * | 2008-05-14 | 2009-11-17 | Medavinci Dev B V | Device and method for separating and analyzing blood. |
WO2009155935A1 (en) * | 2008-06-27 | 2009-12-30 | Toxispot A/S | Cartridge and system for liquid handling automation |
EP2157418A1 (en) * | 2008-07-02 | 2010-02-24 | Koninklijke Philips Electronics N.V. | Fluid providing apparatus |
USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
CN102099676B (en) * | 2008-07-16 | 2016-01-20 | 国际泰克尼迪纳公司 | A kind of cup for blood clot detecting instrument |
JP5188314B2 (en) * | 2008-08-04 | 2013-04-24 | キヤノン株式会社 | Biopolymer testing apparatus and method |
US9201068B2 (en) * | 2008-09-03 | 2015-12-01 | Clarkson University | Bioelectronic tongue for food allergy detection |
US9034277B2 (en) * | 2008-10-24 | 2015-05-19 | Honeywell International Inc. | Surface preparation for a microfluidic channel |
WO2010056732A1 (en) * | 2008-11-12 | 2010-05-20 | Marv Enterprises Llc | Utilization of stents for the treatment of blood borne carcinomas |
EP2359147A1 (en) * | 2008-12-19 | 2011-08-24 | F. Hoffmann-La Roche AG | Device and method for automated verification of the calibration (calibration verification) of an analyzer |
KR101343035B1 (en) * | 2008-12-22 | 2013-12-18 | 삼성전자 주식회사 | Product for analyzing a target material comprising a solid substrate immobilized with first receptor, blocking material and second target material and use thereof |
US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
DE112010000843T5 (en) * | 2009-01-29 | 2012-09-20 | Hitachi High-Technologies Corporation | Device for the pretreatment of samples and mass spectrometers with such a device |
DE202010018623U1 (en) | 2009-02-02 | 2018-12-07 | Opko Diagnostics, Llc | Structures for controlling the light interaction with microfluidic devices |
US20100204936A1 (en) * | 2009-02-11 | 2010-08-12 | Midorion Ab | Probing Electrode/Solution Interfaces |
WO2010107789A1 (en) | 2009-03-17 | 2010-09-23 | Marv Enterprises Llc | Sequential extracorporeal treatment of bodily fluids |
US8195108B2 (en) * | 2009-03-25 | 2012-06-05 | Qualcomm Incorporated | Altitude-dependent power management |
JP5430995B2 (en) | 2009-03-30 | 2014-03-05 | 富士フイルム株式会社 | Assay method and assay device |
WO2010124001A1 (en) * | 2009-04-21 | 2010-10-28 | Advandx, Inc. | Multiplex analysis of cells, particles, and other analytes |
US20120046197A1 (en) | 2009-05-01 | 2012-02-23 | Meso Scale Technologies, Llc | Biomarkers of therapeutic responsiveness |
WO2010127464A1 (en) * | 2009-05-06 | 2010-11-11 | Biocartis Sa | Device for cutting a sample carrier |
US20120058916A1 (en) | 2009-05-13 | 2012-03-08 | Meso Scale Technologies, Llc. | Diagnostic methods for liver disorders |
EP4060331A1 (en) * | 2009-07-27 | 2022-09-21 | Meso Scale Technologies, LLC | Assay information management methods and devices |
US8012770B2 (en) | 2009-07-31 | 2011-09-06 | Invisible Sentinel, Inc. | Device for detection of antigens and uses thereof |
WO2011019533A2 (en) * | 2009-08-13 | 2011-02-17 | Ut-Battelle, Llc | Nucleotide capacitance measurement for low cost dna sequencing |
US8176607B1 (en) | 2009-10-08 | 2012-05-15 | Hrl Laboratories, Llc | Method of fabricating quartz resonators |
ES2461992T3 (en) | 2009-10-09 | 2014-05-22 | Invisible Sentinel, Inc. | Device for the detection of antigens and their uses |
US8862448B2 (en) | 2009-10-19 | 2014-10-14 | Theranos, Inc. | Integrated health data capture and analysis system |
JP5029674B2 (en) * | 2009-11-06 | 2012-09-19 | 富士通株式会社 | Analyte determination device and analyte determination method |
KR20110056168A (en) * | 2009-11-20 | 2011-05-26 | 삼성전자주식회사 | Microfluidic device, light irradiation apparatus, microfluidic system comprising the same and method for driving the system |
EP2504466B1 (en) | 2009-11-23 | 2019-11-20 | Proxim Diagnostics Corporation | Controlled electrochemical activation of carbon-based electrodes |
US10065403B2 (en) | 2009-11-23 | 2018-09-04 | Cyvek, Inc. | Microfluidic assay assemblies and methods of manufacture |
US10022696B2 (en) | 2009-11-23 | 2018-07-17 | Cyvek, Inc. | Microfluidic assay systems employing micro-particles and methods of manufacture |
GB0920526D0 (en) | 2009-11-23 | 2010-01-06 | Ucl Business Plc | Electrochemical detection |
WO2013134745A1 (en) * | 2012-03-08 | 2013-09-12 | Cyvek, Inc | Portable microfluidic assay devices and methods of manufacture and use |
US9500645B2 (en) | 2009-11-23 | 2016-11-22 | Cyvek, Inc. | Micro-tube particles for microfluidic assays and methods of manufacture |
US9855735B2 (en) | 2009-11-23 | 2018-01-02 | Cyvek, Inc. | Portable microfluidic assay devices and methods of manufacture and use |
US9700889B2 (en) | 2009-11-23 | 2017-07-11 | Cyvek, Inc. | Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results |
US9759718B2 (en) | 2009-11-23 | 2017-09-12 | Cyvek, Inc. | PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use |
CA2781556C (en) | 2009-11-23 | 2015-05-19 | Cyvek, Inc. | Method and apparatus for performing assays |
WO2011071772A2 (en) * | 2009-12-07 | 2011-06-16 | Meso Scale Technologies, Llc. | Assay cartridges and methods of using the same |
JP5791634B2 (en) | 2010-01-29 | 2015-10-07 | マイクロニクス, インコーポレイテッド | Sample-response microfluidic cartridge |
JP5065503B2 (en) * | 2010-02-05 | 2012-11-07 | 株式会社シン・コーポレイション | Inspection kit |
JP2011196790A (en) * | 2010-03-18 | 2011-10-06 | Sysmex Corp | Apparatus for analyzing biological component and calibration cartridge |
KR101288244B1 (en) * | 2010-03-19 | 2013-07-26 | 가천대학교 산학협력단 | Biochip |
US20110226071A1 (en) * | 2010-03-19 | 2011-09-22 | Taeyoon Lee | Cartridge |
CN102939160B (en) | 2010-04-16 | 2016-10-12 | 欧普科诊断有限责任公司 | System and device for sample analysis |
WO2011133450A2 (en) | 2010-04-19 | 2011-10-27 | Meso Scale Technologies, Llc. | Serology assays |
US20110266151A1 (en) * | 2010-04-23 | 2011-11-03 | Fredrik Jansson | Microfluidic systems with electronic wettability switches |
US9176092B2 (en) * | 2010-06-11 | 2015-11-03 | Labmaster Oy | Integrated carbon electrode chips for the electric excitation of lanthanide chelates, and analytical methods using these chips |
US20110312712A1 (en) * | 2010-06-17 | 2011-12-22 | Geneasys Pty Ltd | Genetic analysis loc for pcr amplification of nucleic acids from whole blood |
US8912711B1 (en) | 2010-06-22 | 2014-12-16 | Hrl Laboratories, Llc | Thermal stress resistant resonator, and a method for fabricating same |
DE102010038431A1 (en) * | 2010-07-26 | 2012-01-26 | Diasys Diagnostic Systems Gmbh | Measuring cassette and measuring device for the detection of target molecules in a liquid sample by measuring fluorescence emission after excitation in the evanescent field |
EP2599024A4 (en) | 2010-07-27 | 2016-05-04 | Meso Scale Technologies Llc | Consumable data management |
JP5704856B2 (en) * | 2010-08-16 | 2015-04-22 | キヤノン株式会社 | Liquid leak detector, liquid transfer device, and liquid leak detection method |
JP2013536951A (en) | 2010-09-02 | 2013-09-26 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド | Whole blood aspiration pressure monitoring to determine complete blood mixing integrity |
GB201014805D0 (en) * | 2010-09-07 | 2010-10-20 | Multi Sense Technologies Ltd | Microfluidics based assay device |
EP4300100A2 (en) | 2010-10-14 | 2024-01-03 | Meso Scale Technologies, LLC | Reagent storage in an assay device |
EP2628013B1 (en) | 2010-10-14 | 2019-06-12 | The Johns Hopkins University | Biomarkers of brain injury |
US8460607B2 (en) * | 2010-10-22 | 2013-06-11 | Abbott Laboratories | Microfluidic device having a flow channel |
MX336940B (en) * | 2010-10-25 | 2016-02-08 | Hoffmann La Roche | Use of signal enhancing compounds in electrochemiluminescence detection. |
JP5940081B2 (en) * | 2010-11-19 | 2016-06-29 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ カリフォルニアThe Regents of the University of California | Planar hybrid optofluidic integration |
EP2649447A4 (en) * | 2010-12-09 | 2018-06-06 | Akonni Biosystems | Sample analysis system |
KR101737121B1 (en) * | 2010-12-21 | 2017-05-17 | 엘지전자 주식회사 | Microfluidic system |
EP2661485A4 (en) | 2011-01-06 | 2018-11-21 | Meso Scale Technologies, LLC | Assay cartridges and methods of using the same |
WO2012106060A2 (en) | 2011-01-06 | 2012-08-09 | Pepex Biomedical, Inc. | Sensor module with enhanced capillary flow |
EP2666008B1 (en) | 2011-01-21 | 2021-08-11 | Labrador Diagnostics LLC | Systems and methods for sample use maximization |
EP2668501B1 (en) | 2011-01-27 | 2019-06-12 | Invisible Sentinel, Inc. | Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof |
EP2490020A1 (en) * | 2011-02-18 | 2012-08-22 | Koninklijke Philips Electronics N.V. | Measurement chip, microfluidic device and method of measurement chip manufacture |
US10254204B2 (en) | 2011-03-07 | 2019-04-09 | Accelerate Diagnostics, Inc. | Membrane-assisted purification |
ES2551922T3 (en) | 2011-03-07 | 2015-11-24 | Accelerate Diagnostics, Inc. | Rapid cell purification systems |
CN106552682B (en) | 2011-03-22 | 2020-06-19 | 西维克公司 | Microfluidic device and methods of manufacture and use |
JP5723198B2 (en) * | 2011-04-04 | 2015-05-27 | 株式会社エンプラス | Fluid handling device and fluid handling system |
BR112013026451B1 (en) | 2011-04-15 | 2021-02-09 | Becton, Dickinson And Company | system and method to perform molecular diagnostic tests on several samples in parallel and simultaneously amplification in real time in plurality of amplification reaction chambers |
JP6010110B2 (en) * | 2011-04-20 | 2016-10-19 | アクセス メディカル システムズ,リミティド | Repeated amplification of light-emitting polymers. |
EP2527814A1 (en) * | 2011-04-27 | 2012-11-28 | Koninklijke Philips Electronics N.V. | Sensor system with an exchangeable cartridge and a reader |
US20140141458A1 (en) | 2011-05-12 | 2014-05-22 | The Johns Hopkins University | Assay reagents for a neurogranin diagnostic kit |
US8640964B2 (en) * | 2011-06-01 | 2014-02-04 | International Business Machines Corporation | Cartridge for storing biosample plates and use in automated data storage systems |
US9286914B2 (en) | 2011-06-01 | 2016-03-15 | International Business Machines Corporation | Cartridge for storing biosample capillary tubes and use in automated data storage systems |
KR20120134461A (en) * | 2011-06-02 | 2012-12-12 | 삼성전자주식회사 | Micro-fluid supplying device having gas bubble trapping function |
WO2013015822A1 (en) * | 2011-07-25 | 2013-01-31 | Mikhail Briman | Cartridge for diagnostic testing |
US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
WO2013049455A1 (en) * | 2011-09-29 | 2013-04-04 | William Blakely | Biodosimetry panels and methods |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
EP2761305B1 (en) | 2011-09-30 | 2017-08-16 | Becton, Dickinson and Company | Unitized reagent strip |
US8894946B2 (en) * | 2011-10-21 | 2014-11-25 | Integenx Inc. | Sample preparation, processing and analysis systems |
ES2929040T3 (en) * | 2011-10-28 | 2022-11-24 | Aeneas Gmbh & Co Kg | Device and procedure for detecting substances present in biological or chemical samples |
EP2773892B1 (en) | 2011-11-04 | 2020-10-07 | Handylab, Inc. | Polynucleotide sample preparation device |
ITMI20112080A1 (en) * | 2011-11-16 | 2013-05-17 | Eugenio Iannone | PRELIMINARY DIAGNOSIS SYSTEM. |
WO2013075248A1 (en) * | 2011-11-23 | 2013-05-30 | The Governing Council Of The University Of Toronto | Devices and methods for producing planar polymeric materials using microfluidics |
US20130164217A1 (en) | 2011-12-21 | 2013-06-27 | Meso Scale Technologies, Llc | Method of diagnosing, preventing and/or treating dementia & related disorders |
CN103175872A (en) * | 2011-12-23 | 2013-06-26 | 长沙中生众捷生物技术有限公司 | Portable electrochemical detection test strip and preparation method thereof |
US9377475B2 (en) * | 2011-12-23 | 2016-06-28 | Abbott Point Of Care Inc. | Optical assay device with pneumatic sample actuation |
EP2806971A1 (en) | 2012-01-24 | 2014-12-03 | Koninklijke Philips N.V. | Cartridge for processing a fluid |
AU2013214849B2 (en) | 2012-02-03 | 2016-09-01 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
DE102012201843A1 (en) * | 2012-02-08 | 2013-08-08 | Siemens Aktiengesellschaft | Arrangement and method for the electrical detection of liquid samples with lateral flow assays |
MY171654A (en) | 2012-03-05 | 2019-10-22 | Oy Arctic Partners Ab | Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume |
AU2013230917C1 (en) | 2012-03-09 | 2021-09-16 | Invisible Sentinel, Inc. | Methods and compositions for detecting multiple analytes with a single signal |
WO2013136115A1 (en) | 2012-03-13 | 2013-09-19 | Piramal Enterprises Limited | Biosensor having nanostrucured electrodes |
CN107083319A (en) * | 2012-03-16 | 2017-08-22 | 统计诊断与创新有限公司 | Testing cassete with integrated delivery module |
SG11201405788UA (en) * | 2012-03-16 | 2014-11-27 | Life Technologies Corp | Coated substrate for biological reaction systems |
WO2013148405A2 (en) * | 2012-03-27 | 2013-10-03 | Felder Mitchell S | Treatment for atherosclerosis |
DE102012205171B3 (en) | 2012-03-29 | 2013-09-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Integrated disposable chip cartridge system for mobile multi-parameter analysis of chemical and / or biological substances |
US9063037B2 (en) | 2012-05-02 | 2015-06-23 | Stat-Diagnostica & Innovation, S.L. | Swab elution chamber in a test cartridge |
US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
US9081001B2 (en) | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
US9931630B2 (en) * | 2012-06-06 | 2018-04-03 | Instituto De Engenharia De Sistemas E Computadores Para Os Microsistemas E As Nanotecnologias (Inesc-Mn) | Autonomous and programmable sequential flow of solutions in capillary microfluidics |
US10088477B2 (en) * | 2012-07-30 | 2018-10-02 | The Regents Of The University Of California | Biomolecular detection test strip design |
NL2017959B1 (en) * | 2016-12-08 | 2018-06-19 | Illumina Inc | Cartridge assembly |
WO2014043528A1 (en) * | 2012-09-14 | 2014-03-20 | Arizona Board Of Regents For The University Of Arizona | Microfluidic device for biological sample preparation |
WO2014052590A1 (en) * | 2012-09-26 | 2014-04-03 | Ibis Biosciences, Inc. | Swab interface for a microfluidic device |
GB201217390D0 (en) * | 2012-09-28 | 2012-11-14 | Agplus Diagnostics Ltd | Test device and sample carrier |
US9250254B2 (en) | 2012-09-30 | 2016-02-02 | International Business Machines Corporation | Biosample cartridge with radial slots for storing biosample carriers and using in automated data storage systems |
US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
US9957553B2 (en) | 2012-10-24 | 2018-05-01 | Genmark Diagnostics, Inc. | Integrated multiplex target analysis |
US9113570B2 (en) * | 2012-10-31 | 2015-08-18 | Tyco Electronics Services Gmbh | Planar electronic device having a magnetic component |
TWI484182B (en) * | 2012-11-07 | 2015-05-11 | Taidoc Technology Corp | Reaction vessel, assay device, and measuring method |
JP6369330B2 (en) * | 2012-12-19 | 2018-08-08 | コニカミノルタ株式会社 | Sensor chip and SPFS immunofluorescence measurement system using the same |
CN104919035B (en) | 2012-12-21 | 2017-08-11 | 精密公司 | Portable fluorescence detecting system and micro- determination box |
EP2934751B1 (en) | 2012-12-21 | 2019-05-29 | Micronics, Inc. | Low elasticity films for microfluidic use |
US10065186B2 (en) | 2012-12-21 | 2018-09-04 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
CA3170609A1 (en) | 2013-01-03 | 2014-07-10 | Meso Scale Technologies, Llc | Assay panels for a multiplexed analysis of a set of cytokines |
CA3107353A1 (en) | 2013-01-04 | 2014-07-10 | Meso Scale Technologies, Llc. | Assay apparatuses, methods and reagents |
US9050592B2 (en) * | 2013-01-08 | 2015-06-09 | Hewlett-Packard Development Company, L.P. | Liquid dispenser cassette |
JP2016507741A (en) * | 2013-01-09 | 2016-03-10 | バンティックス ホールディングス リミテッド | FT4 electrochemical assay detection system |
AU2014205215B2 (en) * | 2013-01-11 | 2019-02-14 | Becton, Dickinson And Company | Low-cost point-of-care assay device |
JP6409574B2 (en) * | 2013-01-28 | 2018-10-24 | ソニー株式会社 | Impedance measuring apparatus for biological sample and impedance measuring system for biological sample |
EP2950930A1 (en) * | 2013-01-30 | 2015-12-09 | Vantix Holdings Limited | A multi-functional sensor for an electrochemical detection system |
US20140309263A1 (en) | 2013-02-01 | 2014-10-16 | Meso Scale Technologies, Llc | Biomarkers of therapeutic responsiveness |
US20140221368A1 (en) | 2013-02-01 | 2014-08-07 | Meso Scale Technologies, Llc | Biomarkers of therapeutic responsiveness |
US20140220007A1 (en) * | 2013-02-01 | 2014-08-07 | Meso Scale Technologies, Llc | Lupus biomarkers |
US20140220006A1 (en) * | 2013-02-01 | 2014-08-07 | Meso Scale Technologies, Llc | Lung cancer biomarkers |
KR102094496B1 (en) | 2013-03-11 | 2020-03-30 | 큐 헬스 인코퍼레이티드 | Systems and methods for detection and quantification of analytes |
US10545161B2 (en) | 2013-03-11 | 2020-01-28 | Cue Health Inc. | Systems and methods for detection and quantification of analytes |
US9623409B2 (en) | 2013-03-11 | 2017-04-18 | Cue Inc. | Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes |
USD758372S1 (en) * | 2013-03-13 | 2016-06-07 | Nagrastar Llc | Smart card interface |
US9888283B2 (en) | 2013-03-13 | 2018-02-06 | Nagrastar Llc | Systems and methods for performing transport I/O |
EP2972332B1 (en) | 2013-03-14 | 2018-05-30 | Siemens Healthcare Diagnostics Inc. | Microfluidic chip with sealed on-board reagent |
CN105228748B (en) | 2013-03-15 | 2017-10-10 | 金马克诊断股份有限公司 | System, method and apparatus for manipulating deformable fluid container |
US9677109B2 (en) | 2013-03-15 | 2017-06-13 | Accelerate Diagnostics, Inc. | Rapid determination of microbial growth and antimicrobial susceptibility |
RU2671405C2 (en) * | 2013-03-15 | 2018-10-31 | Корамед Текнолоджис, Элэлси | Apparatus, cartridge and method for studying hemostasis parameters |
US9458488B2 (en) * | 2013-03-15 | 2016-10-04 | Nanomix, Inc. | Point of care sensor systems |
US10254279B2 (en) | 2013-03-29 | 2019-04-09 | Nima Labs, Inc. | System and method for detection of target substances |
US10466236B2 (en) * | 2013-03-29 | 2019-11-05 | Nima Labs, Inc. | System and method for detecting target substances |
EP2979092B1 (en) | 2013-03-29 | 2018-05-30 | Nima Labs, Inc. | A portable device for detection of harmful substances |
US9250074B1 (en) | 2013-04-12 | 2016-02-02 | Hrl Laboratories, Llc | Resonator assembly comprising a silicon resonator and a quartz resonator |
EP2992327B1 (en) * | 2013-04-30 | 2018-11-21 | Hewlett-Packard Development Company, L.P. | Microfluidic sensing device and system |
WO2014182844A1 (en) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
WO2014182847A1 (en) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Device for preparation and analysis of nucleic acids |
CA2911303C (en) | 2013-05-07 | 2021-02-16 | Micronics, Inc. | Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions |
WO2015009907A1 (en) | 2013-07-17 | 2015-01-22 | The Johns Hopkins University | A multi-protein biomarker assay for brain injury detection and outcome |
JP2015021906A (en) * | 2013-07-22 | 2015-02-02 | 東亜ディーケーケー株式会社 | Measuring method, cartridge for measurement, and measuring device |
US20150038365A1 (en) * | 2013-08-01 | 2015-02-05 | Meso Scale Technologies, Llc | Lung cancer biomarkers |
KR101504898B1 (en) * | 2013-08-12 | 2015-03-23 | 앰코 테크놀로지 코리아 주식회사 | Micro-fluidic package |
EP3042208A4 (en) | 2013-09-06 | 2017-04-19 | Theranos, Inc. | Systems and methods for detecting infectious diseases |
JP2016532876A (en) | 2013-09-06 | 2016-10-20 | セラノス, インコーポレイテッド | Equipment, systems, methods and kits for receiving wipes |
US9599470B1 (en) | 2013-09-11 | 2017-03-21 | Hrl Laboratories, Llc | Dielectric high Q MEMS shell gyroscope structure |
US9555411B2 (en) * | 2013-09-30 | 2017-01-31 | Gnubio, Inc. | Microfluidic cartridge devices and methods of use and assembly |
USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
US9885012B2 (en) * | 2013-11-05 | 2018-02-06 | Axion Biosystems, Inc. | Devices, systems, and methods for targeted plating of materials in high-throughput culture plates |
CN113477149B (en) | 2013-11-06 | 2023-09-12 | 贝克顿·迪金森公司 | Microfluidic devices and methods of making and using the same |
CN105899936B (en) | 2013-11-13 | 2019-12-24 | 贝克顿·迪金森公司 | Optical imaging system and method of using the same |
US20150182966A1 (en) * | 2013-12-31 | 2015-07-02 | Canon U.S. Life Sciences, Inc. | Field deployable small format fast first result microfluidic system |
WO2015109067A1 (en) * | 2014-01-15 | 2015-07-23 | Canon U.S. Life Sciences, Inc. | Apparatus for optical microfluidics slug edge detection |
GB201401426D0 (en) * | 2014-01-28 | 2014-03-12 | Univ Strathclyde | Automated Assay |
SG11201605507SA (en) * | 2014-01-29 | 2016-08-30 | Hewlett Packard Development Co | Microfluidic valve |
EP3105572B1 (en) | 2014-02-13 | 2019-04-10 | Robert Bosch GmbH | Capacitive bubble detection |
JP2015155841A (en) * | 2014-02-20 | 2015-08-27 | 株式会社村田製作所 | biosensor |
US9977097B1 (en) | 2014-02-21 | 2018-05-22 | Hrl Laboratories, Llc | Micro-scale piezoelectric resonating magnetometer |
TWI482963B (en) * | 2014-03-05 | 2015-05-01 | Coretronic Corp | Hydrophilic film and manufacturing method thereof, and organism sensor using the hydrophilic film |
KR20160130459A (en) * | 2014-03-07 | 2016-11-11 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | Tri-electrode apparatus and methods for molecular analysis |
JP5931111B2 (en) * | 2014-03-31 | 2016-06-08 | ミネベア株式会社 | Detection device |
JP2015201646A (en) | 2014-04-07 | 2015-11-12 | ラム リサーチ コーポレーションLam Research Corporation | Configuration independent gas delivery system |
US9991863B1 (en) | 2014-04-08 | 2018-06-05 | Hrl Laboratories, Llc | Rounded and curved integrated tethers for quartz resonators |
JP2017510822A (en) * | 2014-04-11 | 2017-04-13 | レオセンス,インコーポレイテッド | Viscometer and method of use thereof |
AT515762B1 (en) * | 2014-04-15 | 2016-02-15 | Seibersdorf Labor Gmbh | Dispensing device for dispensing liquids |
BR112016022867A2 (en) * | 2014-04-25 | 2018-07-03 | Hewlett Packard Development Co | diagnostic cassette. |
ES2552709B1 (en) * | 2014-04-29 | 2016-10-07 | Consejo Superior De Investigaciones Científicas (Csic) | MODULAR LIGHT BEAM ANALYSIS SYSTEM |
CA3229509A1 (en) | 2014-05-09 | 2015-11-12 | Meso Scale Technologies, Llc. | Graphene-modified electrodes |
USD745423S1 (en) | 2014-05-12 | 2015-12-15 | Cue Inc. | Automated analyzer test cartridge and sample collection device for analyte detection |
TWI549745B (en) | 2014-05-16 | 2016-09-21 | 財團法人工業技術研究院 | Apparatus and method for mixing solution and monitoring particles in solution |
TWI583439B (en) * | 2014-05-16 | 2017-05-21 | 財團法人工業技術研究院 | Apparatus and method for mixing solution |
WO2015183792A1 (en) * | 2014-05-27 | 2015-12-03 | Case Western Reserve University | Electrochemical sensor for analyte detection |
US11009479B2 (en) | 2014-05-27 | 2021-05-18 | Case Western Reserve University | Systems and methods for the detection of HbA1c |
PT3158317T (en) | 2014-06-18 | 2019-12-10 | Zoetis Denmark Aps | A microfluidic detection system |
JP6515677B2 (en) * | 2014-07-24 | 2019-05-22 | ソニー株式会社 | Contact structure and electrical measurement apparatus for biological sample using the contact structure |
KR20160018201A (en) * | 2014-08-08 | 2016-02-17 | 삼성전자주식회사 | Fluid analysis cartridge and fluid analysis apparatus having the same |
US10308505B1 (en) | 2014-08-11 | 2019-06-04 | Hrl Laboratories, Llc | Method and apparatus for the monolithic encapsulation of a micro-scale inertial navigation sensor suite |
WO2016029288A1 (en) * | 2014-08-26 | 2016-03-03 | Narwhal Analytical Corporation (Ontario Corporation Number 002408580) | Mini-fluidics cassette for colorimetric nutrient analysis and a method of using same |
CA2959992A1 (en) | 2014-09-04 | 2016-03-10 | Theranos, Inc. | Pathogen and antimicrobial resistance testing |
US10222386B2 (en) | 2014-09-19 | 2019-03-05 | The Johns Hopkins University | Biomarkers of congnitive dysfunction |
EP3198270A1 (en) | 2014-09-26 | 2017-08-02 | Abbott Point Of Care, Inc. | Cartridge device with fluidic junctions for coagulation assays in fluid samples |
CN106999931B (en) | 2014-09-26 | 2020-08-18 | 雅培医护站股份有限公司 | Microfabricated device with micro-environment sensor for determining coagulation in fluid sample |
EP3198271B1 (en) | 2014-09-26 | 2022-03-02 | Abbott Point Of Care, Inc. | Single channel cartridge device for blood coagulation assays in fluid samples |
WO2016049552A1 (en) | 2014-09-26 | 2016-03-31 | Abbott Point Of Care Inc. | Cartridge device identification for coagulation assays in fluid samples |
EP3197603A1 (en) | 2014-09-26 | 2017-08-02 | Abbott Point of Care Inc. | Cartridge device with segmented fluidics for assaying coagulation in fluid samples |
EP3955003B1 (en) * | 2014-09-26 | 2023-06-21 | Abbott Point Of Care Inc | Sensors for assaying coagulation in fluid samples |
US9921232B2 (en) | 2014-09-26 | 2018-03-20 | Abbott Point Of Care Inc. | Ellagic acid formulations for use in coagulation assays |
US9897618B2 (en) | 2014-09-29 | 2018-02-20 | C A Casyso Gmbh | Blood testing system |
US10288630B2 (en) | 2014-09-29 | 2019-05-14 | C A Casyso Gmbh | Blood testing system and method |
US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
US10816559B2 (en) | 2014-09-29 | 2020-10-27 | Ca Casyso Ag | Blood testing system and method |
US10175225B2 (en) | 2014-09-29 | 2019-01-08 | C A Casyso Ag | Blood testing system and method |
JP6476705B2 (en) * | 2014-10-02 | 2019-03-06 | 東洋紡株式会社 | Pretreatment method for antigen detection |
US10557197B2 (en) | 2014-10-17 | 2020-02-11 | Lam Research Corporation | Monolithic gas distribution manifold and various construction techniques and use cases therefor |
WO2016065190A1 (en) * | 2014-10-23 | 2016-04-28 | Abbott Diabetes Care Inc. | Electrodes having at least one sensing structure and methods for making and using the same |
AU2015353618C1 (en) | 2014-11-24 | 2018-12-13 | Ppg Industries Ohio, Inc. | Methods for reactive three-dimensional printing by inkjet printing |
US9784685B2 (en) * | 2014-12-10 | 2017-10-10 | Molecular Devices, Inc. | Liquid and plate sensors for microplate injector system |
KR20160081022A (en) * | 2014-12-30 | 2016-07-08 | 삼성전자주식회사 | Microfluidic device and method of detecting sample supplied to the same |
KR20160081669A (en) * | 2014-12-31 | 2016-07-08 | 삼성전자주식회사 | Reaction apparatus, test device and control method for the test device |
US10031191B1 (en) | 2015-01-16 | 2018-07-24 | Hrl Laboratories, Llc | Piezoelectric magnetometer capable of sensing a magnetic field in multiple vectors |
CN104597094B (en) * | 2015-01-22 | 2017-02-22 | 北京农业智能装备技术研究中心 | Device for detecting dynamic ion flow of vegetable living body |
EP3254067A4 (en) | 2015-02-06 | 2018-07-18 | Genapsys Inc. | Systems and methods for detection and analysis of biological species |
US11041865B2 (en) | 2015-02-20 | 2021-06-22 | The Johns Hopkins University | Biomarkers of myocardial injury |
WO2016149253A1 (en) * | 2015-03-16 | 2016-09-22 | Dots Technology Corp. | Portable allergen detection system |
US10253355B2 (en) | 2015-03-30 | 2019-04-09 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing |
US10023895B2 (en) | 2015-03-30 | 2018-07-17 | Accelerate Diagnostics, Inc. | Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing |
USD864968S1 (en) | 2015-04-30 | 2019-10-29 | Echostar Technologies L.L.C. | Smart card interface |
US10611505B2 (en) * | 2015-05-04 | 2020-04-07 | Rai Strategic Holdings, Inc. | Dispensing machine for aerosol precursor |
US10295554B2 (en) | 2015-06-29 | 2019-05-21 | C A Casyso Gmbh | Blood testing system and method |
US10930383B2 (en) | 2015-07-03 | 2021-02-23 | Cuepath Innovation Inc. | Connected sensor substrate for blister packs |
CN105021807B (en) * | 2015-07-03 | 2016-08-31 | 艾康生物技术(杭州)有限公司 | Reagent reacting box and the application in biology sample detection thereof |
CN105021544B (en) * | 2015-07-03 | 2018-02-02 | 艾康生物技术(杭州)有限公司 | Detecting system |
CA2991253C (en) * | 2015-07-03 | 2022-05-10 | Cuepath Innovation Inc. | Connected sensor substrate for blister packs |
CN105137091B (en) * | 2015-07-03 | 2017-10-10 | 艾康生物技术(杭州)有限公司 | Reagent storing device |
CN105013546B (en) | 2015-07-03 | 2017-12-08 | 艾康生物技术(杭州)有限公司 | Biological sample reaction box |
US10928399B2 (en) | 2015-07-15 | 2021-02-23 | Hycor Biomedical, Llc | Customizable instrument |
KR102604091B1 (en) | 2015-07-17 | 2023-11-22 | 큐 헬스 인코퍼레이티드 | Systems and methods for enhanced detection and quantitation of analytes |
US10022689B2 (en) | 2015-07-24 | 2018-07-17 | Lam Research Corporation | Fluid mixing hub for semiconductor processing tool |
US20170059561A1 (en) * | 2015-08-28 | 2017-03-02 | The Florida International University Board Of Trustees | Thermally Stable Electrochemical Sensor With Long Shelf-Life |
US10118263B2 (en) | 2015-09-02 | 2018-11-06 | Lam Researech Corporation | Monolithic manifold mask and substrate concepts |
CN105223259B (en) * | 2015-09-29 | 2018-05-04 | 南京工业大学 | A kind of Portable heavy metal ion device for fast detecting and application process |
DE102015219023B3 (en) * | 2015-10-01 | 2017-02-23 | Technische Universität München | Apparatus for analyzing biological substances in a test solution, manufacturing method and method of operation |
WO2017087759A1 (en) * | 2015-11-18 | 2017-05-26 | President And Fellows Of Harvard College | Cartridge-based system for long term culture of cell clusters |
US10228367B2 (en) | 2015-12-01 | 2019-03-12 | ProteinSimple | Segmented multi-use automated assay cartridge |
WO2017096293A1 (en) * | 2015-12-03 | 2017-06-08 | Ca Casyso Ag | Blood testing system and method |
US10110198B1 (en) | 2015-12-17 | 2018-10-23 | Hrl Laboratories, Llc | Integrated quartz MEMS tuning fork resonator/oscillator |
EP3403082A4 (en) * | 2016-01-13 | 2019-08-28 | ProteinSimple | Systems and methods for capillary electrophoresis, isoelectric point, and molecular weight analysis |
US10215317B2 (en) | 2016-01-15 | 2019-02-26 | Lam Research Corporation | Additively manufactured gas distribution manifold |
US9879795B2 (en) * | 2016-01-15 | 2018-01-30 | Lam Research Corporation | Additively manufactured gas distribution manifold |
US10175307B1 (en) | 2016-01-15 | 2019-01-08 | Hrl Laboratories, Llc | FM demodulation system for quartz MEMS magnetometer |
WO2017127120A1 (en) * | 2016-01-22 | 2017-07-27 | Hewlett-Packard Development Company, L.P. | Fluid sensing with control of particle aggregation in sensing zone |
ES2770223T3 (en) * | 2016-01-29 | 2020-07-01 | Hoffmann La Roche | Electrochemiluminescence procedure and apparatus for detecting an analyte in a liquid sample |
US10656151B2 (en) * | 2016-01-29 | 2020-05-19 | Ortho-Clinical Diagnostics, Inc. | Air capillary vent for a lateral flow assay device |
GB2547930A (en) * | 2016-03-03 | 2017-09-06 | Sepsense Ltd | Assay device |
DE102016106563A1 (en) * | 2016-04-11 | 2017-10-12 | Meyer Burger (Germany) Ag | Method for producing a solar cell, solar cell produced by the method and substrate carrier |
NZ720675A (en) * | 2016-05-31 | 2017-07-28 | Crime Scene Solutions Ltd | Improved collection and storage apparatus |
GB201611442D0 (en) | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Fluid control |
EP3488031A4 (en) | 2016-07-22 | 2020-09-16 | Meso Scale Technologies, LLC | Integrated consumable data management system & platform |
US20190353614A1 (en) | 2016-08-15 | 2019-11-21 | University Of Tasmania | Inorganic ion detection system and methods |
US10473674B2 (en) | 2016-08-31 | 2019-11-12 | C A Casyso Gmbh | Controlled blood delivery to mixing chamber of a blood testing cartridge |
GB201615472D0 (en) | 2016-09-12 | 2016-10-26 | Fluidic Analytics Ltd | Improvements in or relating to a reagent cartridge |
WO2018065107A1 (en) * | 2016-10-07 | 2018-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Cartridge for testing a sample and method for producing a cartridge of this kind |
CN109803761B (en) | 2016-10-07 | 2022-09-13 | 勃林格殷格翰维特梅迪卡有限公司 | Analysis device and method for detecting sample |
WO2018065102A1 (en) | 2016-10-07 | 2018-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Method and analysis system for testing a sample |
US20180099276A1 (en) * | 2016-10-07 | 2018-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Analysis system and method for testing a sample |
US10751714B2 (en) * | 2016-10-07 | 2020-08-25 | Boehringer Ingelheim Vetmedica Gmbh | Cartridge for testing a sample |
TWI781669B (en) * | 2016-10-14 | 2022-10-21 | 美商伊路米納有限公司 | Cartridge assembly |
WO2018140540A1 (en) | 2017-01-25 | 2018-08-02 | Cue Health Inc. | Systems and methods for enhanced detection and quantification of analytes |
US10759554B2 (en) | 2017-02-02 | 2020-09-01 | Rai Strategic Holdings, Inc. | Dispenser unit for aerosol precursor |
US11364498B2 (en) | 2017-04-07 | 2022-06-21 | Hewlett-Packard Development Company, L.P. | Microfluidic devices |
US10677709B2 (en) * | 2017-04-28 | 2020-06-09 | Becton, Dickinson And Company | Particle detection cartridges, systems thereof and methods for using the same |
KR20200033800A (en) * | 2017-05-04 | 2020-03-30 | 유니베르시태트 취리히 | Cell culture device |
WO2018226163A1 (en) * | 2017-06-08 | 2018-12-13 | National University Of Singapore | Modular microfluidic assay system |
US11215545B2 (en) * | 2017-06-14 | 2022-01-04 | Cytochip Inc. | Devices and methods for cell analysis |
EP3418721A1 (en) * | 2017-06-23 | 2018-12-26 | Cellix Limited | A microfluidic chip |
US10843185B2 (en) | 2017-07-12 | 2020-11-24 | Ca Casyso Gmbh | Autoplatelet cartridge device |
US10926256B2 (en) * | 2017-07-12 | 2021-02-23 | Sharp Life Science (Eu) Limited | Housing for simple assembly of an EWOD device |
DE102017213158A1 (en) | 2017-07-31 | 2019-01-31 | Technische Universität München | Sensor arrangement for analyzing substances in a substance and method for operating such a sensor arrangement |
JP7110320B2 (en) * | 2017-08-01 | 2022-08-01 | エフ.ホフマン-ラ ロシュ アーゲー | Method for monitoring the operation of detecting an analyte in a liquid sample |
CN107505381A (en) * | 2017-08-21 | 2017-12-22 | 中华人民共和国南京出入境检验检疫局 | Portable USB interface heavy metal ion detection device and electrode card |
WO2019060375A1 (en) | 2017-09-19 | 2019-03-28 | Beckman Coulter, Inc. | System for analog light measuring and photon counting in chemiluminescence measurements |
WO2019079681A1 (en) | 2017-10-20 | 2019-04-25 | President And Fellows Of Harvard College | Methods for producing mature adipocytes and methods of use thereof |
US11491487B2 (en) | 2017-10-23 | 2022-11-08 | Cytochip Inc. | Devices and methods for measuring analytes and target particles |
KR20200086302A (en) | 2017-11-02 | 2020-07-16 | 메메드 다이어그노스틱스 리미티드 | Cartridges and systems for body fluid analysis |
EP3710790A4 (en) * | 2017-11-17 | 2021-01-20 | Siemens Healthcare Diagnostics, Inc. | Sensor assembly and method of using same |
CN107764836B (en) * | 2017-11-22 | 2023-11-07 | 湖南正中制药机械有限公司 | Automatic quality detector for plastic ampoule in row |
US11287404B2 (en) * | 2017-12-21 | 2022-03-29 | International Business Machines Corporation | Analysis apparatus with spectrometer |
NL2020616B1 (en) | 2018-02-03 | 2019-08-14 | Illumina Inc | Cartridge with laminated manifold |
EP3752290B1 (en) * | 2018-02-15 | 2023-08-23 | Siemens Healthcare Diagnostics Inc. | Methods of using a diagnostic assay cartridge for conducting multiple diagnostic assays on a patient's single liquid test sample |
WO2019173703A1 (en) | 2018-03-08 | 2019-09-12 | Meso Scale Technologies, Llc. | Genetic marker and/or biomarkers for traumatic brain injury, and ultrasensitive assays for biomarkers of traumatic brain injury |
CN108398470B (en) * | 2018-04-13 | 2024-01-30 | 广州万孚生物技术股份有限公司 | Biosensor for measuring blood activation clotting time and manufacturing method thereof |
AU2019261360A1 (en) * | 2018-04-23 | 2020-03-05 | Anpac Bio-Medical Science Co., Ltd. | New apparatus and methods for disease detection |
JP2019190977A (en) * | 2018-04-25 | 2019-10-31 | 株式会社バイオデバイステクノロジー | Microchip, microchip measurement system and measurement method |
WO2019236632A1 (en) | 2018-06-04 | 2019-12-12 | Avon Products. Inc. | Protein biomarkers for identifying and treating aging skin and skin conditions |
US11131615B2 (en) | 2018-06-07 | 2021-09-28 | Nanohmics, Inc. | Sensor and methods for detecting and quantifying ions and molecules |
CA3101880A1 (en) * | 2018-06-19 | 2019-12-26 | Avails Medical, Inc. | Devices, systems, and methods for measuring a solution characteristic of a sample comprising microorganisms |
CA3105025C (en) * | 2018-06-29 | 2021-11-02 | Siemens Healthcare Diagnostics Inc. | Stacked sensor assembly for fluid analyzer |
CN109187448B (en) * | 2018-07-25 | 2021-08-13 | 西安交通大学 | Multi-target disc type lateral flow test paper chip and laser cutting preparation method, use method, application and detection device thereof |
WO2020032958A1 (en) * | 2018-08-09 | 2020-02-13 | Hewlett-Packard Development Company, L.P. | Conductivity-based reaction chamber control |
WO2020032956A1 (en) * | 2018-08-09 | 2020-02-13 | Hewlett-Packard Development Company, L.P. | Microfluidic devices with impedance setting to set backpressure |
USD888269S1 (en) | 2018-09-02 | 2020-06-23 | Memed Diagnostics Ltd. | Capillary blood collector device |
USD951482S1 (en) | 2018-09-02 | 2022-05-10 | Memed Diagnostics Ltd. | Cartridge device |
US11351540B2 (en) * | 2018-10-04 | 2022-06-07 | International Business Machines Corporation | Covert codes based on electrical sensing of patterned materials in microfluidic devices |
US10753986B2 (en) * | 2018-10-04 | 2020-08-25 | Genmark Diagnostics, Inc. | Systems and methods for assessing electrical connectivity between elements of assay devices |
US10352983B1 (en) * | 2018-10-04 | 2019-07-16 | Genmark Diagnostics, Inc. | Systems and methods for assessing electrical connectivity between elements of assay devices |
US20200123589A1 (en) * | 2018-10-19 | 2020-04-23 | Avalon HepaPOC Limited | Galactose rapid quantitative detection system and use thereof |
CN109374375B (en) * | 2018-10-31 | 2021-03-02 | 中国海洋石油集团有限公司 | Rock sample preparation method for measuring contact angle |
DE102018219952A1 (en) * | 2018-11-21 | 2020-05-28 | Continental Automotive Gmbh | Method for determining an electrical fault in a conductivity sensor and conductivity sensor |
WO2020142839A1 (en) * | 2019-01-07 | 2020-07-16 | 1866402 Ontario Inc. | Blood separation and analysis device and methods |
KR102537828B1 (en) * | 2019-02-11 | 2023-05-26 | 피피지 인더스트리즈 오하이오 인코포레이티드 | Methods of manufacturing chemical-resistant sealing components |
WO2020167828A1 (en) * | 2019-02-11 | 2020-08-20 | Giner, Inc. | Method and system for detection and/or quantification of delta-9-tetrahydrocannabinol in exhaled breath |
EP4349601A2 (en) * | 2019-02-11 | 2024-04-10 | PPG Industries Ohio, Inc. | Coreactive three-dimensional printing of parts |
EP3942059A4 (en) * | 2019-03-04 | 2022-04-20 | Siemens Healthcare Diagnostics, Inc. | Dried reagent polysaccharide surface area stabilization |
US20220212191A1 (en) * | 2019-03-26 | 2022-07-07 | Siemens Healthcare Diagnostics Inc. | System for delivering fluid samples through a fluidic device and methods therefor |
US11717202B2 (en) | 2019-04-10 | 2023-08-08 | Foothold Labs Inc. | Mobile lab-on-a-chip diagnostic system |
CN110004044A (en) * | 2019-04-25 | 2019-07-12 | 湖南工业大学 | A kind of Molecular Detection integration device and its detection method based on electrochemical sensing |
US10989634B2 (en) | 2019-04-29 | 2021-04-27 | Ankom Technology Corporation | Systems and methods for extracting analytes from a sample |
US20220065815A1 (en) * | 2019-05-07 | 2022-03-03 | Hewlett-Packard Development Company, L.P. | Fluid identification via electrochemical labels |
RU194024U1 (en) * | 2019-07-15 | 2019-11-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Государственный университет морского и речного флота имени адмирала С.О. Макарова" | DEVICE FOR CONTROL OF THE TECHNICAL CONDITION OF CONSTRUCTION STRUCTURES |
WO2021066744A1 (en) * | 2019-09-30 | 2021-04-08 | Illumina Singapore Pte. Ltd. | Test cartridge for analysis instruments |
US11697807B2 (en) | 2019-09-30 | 2023-07-11 | Case Western Reserve University | Electrochemical biosensor |
US20220362767A1 (en) * | 2019-10-25 | 2022-11-17 | Fabrico Technology, Inc. | Systems and methods for measuring colorimetric reactions |
DE102019217927A1 (en) * | 2019-10-25 | 2021-04-29 | Robert Bosch Gmbh | Cartridge with a microfluidic system and electrical components |
CA3160211A1 (en) | 2019-11-05 | 2021-05-14 | Meso Scale Technologies, Llc. | Methods and kits for quantitating radiation exposure |
US20230021837A1 (en) | 2019-11-26 | 2023-01-26 | Meso Scale Technologies, Llc. | Methods and kits for detecting autoimmune diseases |
CN110823749B (en) * | 2019-11-26 | 2022-07-05 | 陕西延长石油(集团)有限责任公司 | Multifunctional high-pressure reaction evaluation device and method |
JP7278933B2 (en) * | 2019-12-09 | 2023-05-22 | 富士フイルム株式会社 | inspection container |
IL294562A (en) * | 2020-01-06 | 2022-09-01 | Bisu Inc | Microfluidic system, device and method |
TW202136735A (en) * | 2020-01-13 | 2021-10-01 | 英商盧米瑞德克斯英國有限公司 | Fluid control in microfluidic devices |
JP7207663B2 (en) * | 2020-03-11 | 2023-01-18 | Tdk株式会社 | analysis chip |
US10953404B1 (en) * | 2020-04-24 | 2021-03-23 | Pattern Bioscience, Inc. | Apparatuses for contactless loading and imaging of microfluidic chips and related methods |
US20230184768A1 (en) | 2020-05-01 | 2023-06-15 | Meso Scale Technologies, Llc. | Viral serology ace2 competition assays |
EP4154008A1 (en) | 2020-05-19 | 2023-03-29 | Meso Scale Technologies, LLC | Methods, compositions, and kits for nucleic acid detection |
US20230226552A1 (en) * | 2020-06-24 | 2023-07-20 | Illumina, Inc. | Dry reagent cup assemblies and methods |
WO2022040529A2 (en) | 2020-08-21 | 2022-02-24 | Meso Scale Technologies, Llc. | Auxiliary electrodes and methods for using and manufacturing the same |
US20230143974A1 (en) * | 2020-11-11 | 2023-05-11 | Rhazes S.R.L. | Portable device for detecting and quantifying a concentration of a marker present in a sample of biological fluid |
CN112147184B (en) * | 2020-11-24 | 2021-04-23 | 南京仪汇仪器设备有限公司 | Asphalt flash point detection device |
FR3116461B1 (en) * | 2020-11-26 | 2022-12-23 | S A S 3Dceram Sinto | Machine for manufacturing raw parts in ceramic or metallic material |
IT202100007136A1 (en) * | 2021-03-24 | 2022-09-24 | I Tech S R L | DEVICE FOR THE TRANSFER OF LIQUID PRODUCTS |
WO2022221660A1 (en) | 2021-04-16 | 2022-10-20 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for detecting hydrolase enzyme activity |
EP4337931A1 (en) * | 2021-05-11 | 2024-03-20 | Ceidos SA | Cell culture monitoring system and dielectrophoresis cartridge |
EP4089395A1 (en) * | 2021-05-11 | 2022-11-16 | Ceidos SA | Cell culture monitoring system |
EP4341692A1 (en) | 2021-05-21 | 2024-03-27 | Meso Scale Technologies, LLC | Viral strain serology assays |
AU2022304570A1 (en) | 2021-06-28 | 2024-01-18 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for assay signal amplification |
DE102021121040A1 (en) * | 2021-08-12 | 2023-02-16 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein | Method and device for the simultaneous determination of the electrochemical activity of a plurality of materials |
CA3228270A1 (en) | 2021-08-13 | 2023-02-16 | Meso Scale Technologies, Llc. | Electrochemical cell devices and methods of manufacturing |
CN114214177A (en) * | 2021-12-07 | 2022-03-22 | 广州国家实验室 | Microfluidic chip, detection kit and exosome detection method |
WO2023104927A1 (en) * | 2021-12-07 | 2023-06-15 | Analog Devices International Unlimited Company | Sensor assembly and method of manufacture |
GB202118917D0 (en) * | 2021-12-23 | 2022-02-09 | Osler Diagnostics Ltd | Liquid handling method, system and device |
DE102022201532A1 (en) | 2022-02-15 | 2023-08-17 | Robert Bosch Gesellschaft mit beschränkter Haftung | Procedure for calibrating an analysis system for lab-on-chip cartridges |
CN114563331B (en) * | 2022-03-22 | 2023-12-19 | 重庆市公共卫生医疗救治中心 | Automatic counting and detecting system for CD4+T lymphocyte based on micro-fluidic chip |
WO2023245184A1 (en) | 2022-06-17 | 2023-12-21 | Meso Scale Technologies, Llc. | Viral strain serology assays |
EP4310489A1 (en) * | 2022-07-21 | 2024-01-24 | ETH Zurich | Assay device for electrochemical sensing of a sample fluid |
US20240103002A1 (en) | 2022-09-23 | 2024-03-28 | Meso Scale Technologies, Llc. | Orthopoxvirus serology assays |
WO2023174438A2 (en) * | 2023-04-14 | 2023-09-21 | 杭州柔谷科技有限公司 | Reproductive hormone test system, and flexible sensing electrode and preparation method therefor |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4014206A (en) * | 1975-03-31 | 1977-03-29 | Akron City Hospital | Apparatus and method for monitoring air emboli during extracorporeal circulation |
US5399256A (en) * | 1994-01-07 | 1995-03-21 | Bioanalytical Systems, Inc. | Electrochemical detector cell |
US6264825B1 (en) * | 1998-06-23 | 2001-07-24 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
US6403367B1 (en) * | 1994-07-07 | 2002-06-11 | Nanogen, Inc. | Integrated portable biological detection system |
US6440662B1 (en) * | 1995-12-01 | 2002-08-27 | Innogenetics N.V. | Impedimetric detection system and method of production thereof |
US6673533B1 (en) * | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
Family Cites Families (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3815580A (en) | 1972-08-31 | 1974-06-11 | C Oster | Apparatus for and method of collecting and preserving cytologic samples |
US3918435A (en) * | 1974-01-24 | 1975-11-11 | Miles Lab | Transport swab tube |
GB2059992B (en) * | 1979-10-11 | 1983-10-19 | Pike B R | Culture-collecting kit and a method of taking a culture sample utilising it |
US4586604A (en) * | 1984-06-28 | 1986-05-06 | Continental Plastic Corporation | Culture collection instrument and sealed swab holder therefor |
US4663230A (en) | 1984-12-06 | 1987-05-05 | Hyperion Catalysis International, Inc. | Carbon fibrils, method for producing same and compositions containing same |
US5165909A (en) | 1984-12-06 | 1992-11-24 | Hyperion Catalysis Int'l., Inc. | Carbon fibrils and method for producing same |
US5171560A (en) | 1984-12-06 | 1992-12-15 | Hyperion Catalysis International | Carbon fibrils, method for producing same, and encapsulated catalyst |
DE8500471U1 (en) * | 1985-01-10 | 1985-05-02 | Burkhardt, Friedrich, Prof. Dr. med., 8520 Erlangen | Plastic shipping container for the preservation of medical examination material |
US4803998A (en) * | 1986-01-27 | 1989-02-14 | Ncs Diagnostics, Inc. | Swab retaining vial cap and method of use |
US5147806A (en) * | 1988-04-29 | 1992-09-15 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescence measurements |
US4813432A (en) * | 1987-10-13 | 1989-03-21 | Saint-Amand Manufacturing, Inc. | Swab transport system |
US4978504A (en) * | 1988-02-09 | 1990-12-18 | Nason Frederic L | Specimen test unit |
US5266266A (en) * | 1988-02-09 | 1993-11-30 | Nason Frederic L | Specimen test unit |
DE68924026T3 (en) * | 1988-03-31 | 2008-01-10 | Matsushita Electric Industrial Co., Ltd., Kadoma | BIOSENSOR AND ITS MANUFACTURE. |
JPH0259466U (en) * | 1988-10-20 | 1990-05-01 | ||
US5705402A (en) * | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
US5746974A (en) * | 1988-11-03 | 1998-05-05 | Igen International, Inc. | Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection |
CA1338505C (en) * | 1989-02-03 | 1996-08-06 | John Bruce Findlay | Containment cuvette for pcr and method of use |
NO168369C (en) * | 1989-09-18 | 1992-02-12 | Bionor As | COLLECTION AND TRANSPORT SYSTEM FOR CULTURES OF MICRO-ORGANISMS |
GB8921609D0 (en) | 1989-09-25 | 1989-11-08 | Wright Christopher L | Improvements in or relating to a waterproof membrane |
DE59109048D1 (en) * | 1990-02-14 | 1998-10-15 | Pentapharm Ag | Inhibitors for the anticoagulant pretreatment of blood samples |
US5302274A (en) * | 1990-04-16 | 1994-04-12 | Minitech Co. | Electrochemical gas sensor cells using three dimensional sensing electrodes |
US5264103A (en) * | 1991-10-18 | 1993-11-23 | Matsushita Electric Industrial Co., Ltd. | Biosensor and a method for measuring a concentration of a substrate in a sample |
US5290518A (en) * | 1992-08-17 | 1994-03-01 | Eastman Kodak Company | Flexible extraction device with burstable sidewall |
WO1994004929A1 (en) * | 1992-08-24 | 1994-03-03 | Baxter Diagnostics Inc. | Sealable vessel for containing and processing analytical samples |
WO1994011054A1 (en) * | 1992-11-09 | 1994-05-26 | Sipin Anatole J | Controlled fluid transfer system |
US5415994A (en) * | 1993-08-02 | 1995-05-16 | Quidel Corporation | Lateral flow medical diagnostic assay device with sample extraction means |
US5609749A (en) * | 1993-12-29 | 1997-03-11 | Mochida Pharmaceutical Co., Ltd. | Electrochemical assay method with novel p-phenylenediamine compound |
AU1911795A (en) * | 1994-02-09 | 1995-08-29 | Abbott Laboratories | Diagnostic flow cell device |
US5437999A (en) * | 1994-02-22 | 1995-08-01 | Boehringer Mannheim Corporation | Electrochemical sensor |
KR0151203B1 (en) * | 1994-12-08 | 1998-12-01 | 이헌조 | Multi-electrode type biosensor |
WO1996028538A1 (en) * | 1995-03-10 | 1996-09-19 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
CN1095641C (en) * | 1995-06-23 | 2002-12-11 | 盖拉斯医疗有限公司 | Electrosurgical instrument |
US20020022261A1 (en) * | 1995-06-29 | 2002-02-21 | Anderson Rolfe C. | Miniaturized genetic analysis systems and methods |
WO1998028623A1 (en) * | 1996-12-20 | 1998-07-02 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
US6391558B1 (en) * | 1997-03-18 | 2002-05-21 | Andcare, Inc. | Electrochemical detection of nucleic acid sequences |
JP4208392B2 (en) * | 1997-08-01 | 2009-01-14 | キヤノン株式会社 | Liquid composition for ejecting probe by inkjet method |
US6440725B1 (en) * | 1997-12-24 | 2002-08-27 | Cepheid | Integrated fluid manipulation cartridge |
US6475360B1 (en) * | 1998-03-12 | 2002-11-05 | Lifescan, Inc. | Heated electrochemical cell |
US6248294B1 (en) * | 1998-04-15 | 2001-06-19 | Frederic L. Nason | Self contained diagnostic test unit |
US6200531B1 (en) * | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
US6245065B1 (en) * | 1998-09-10 | 2001-06-12 | Scimed Life Systems, Inc. | Systems and methods for controlling power in an electrosurgical probe |
JP3482140B2 (en) * | 1998-10-06 | 2003-12-22 | 株式会社東芝 | Nucleic acid chain synthesis method, nucleic acid immobilized chip and nucleic acid chain detection method |
US6630663B2 (en) * | 1998-10-21 | 2003-10-07 | Raytheon Company | Miniature ion mobility spectrometer |
FR2789401B1 (en) * | 1999-02-08 | 2003-04-04 | Cis Bio Int | METHOD FOR MANUFACTURING LIGAND DIES ADDRESSED ON A MEDIUM |
US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
EP1183104B1 (en) * | 1999-05-14 | 2006-10-25 | Gen-Probe Incorporated | Penetrable cap with inner apex |
ATE278771T1 (en) * | 1999-05-28 | 2004-10-15 | Cepheid | APPARATUS AND METHOD FOR ANALYZING LIQUID SAMPLES |
DK1181098T4 (en) * | 1999-05-28 | 2011-09-26 | Cepheid | Cartridge for performing a chemical reaction |
CN2393493Y (en) * | 1999-07-16 | 2000-08-30 | 北京三早生物工程技术有限公司 | Early cancer diagnoser |
JP2001133436A (en) * | 1999-11-01 | 2001-05-18 | Microtec Nition:Kk | Matrix type substrate for electrochemical emission |
US6616819B1 (en) * | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
US6589729B2 (en) * | 2000-02-04 | 2003-07-08 | Caliper Technologies Corp. | Methods, devices, and systems for monitoring time dependent reactions |
JP4261077B2 (en) * | 2000-03-16 | 2009-04-30 | 株式会社東芝 | Method for producing nucleic acid chain-immobilized carrier |
US6471696B1 (en) * | 2000-04-12 | 2002-10-29 | Afx, Inc. | Microwave ablation instrument with a directional radiation pattern |
US6557427B2 (en) * | 2000-05-24 | 2003-05-06 | Micronics, Inc. | Capillaries for fluid movement within microfluidic channels |
US6645432B1 (en) * | 2000-05-25 | 2003-11-11 | President & Fellows Of Harvard College | Microfluidic systems including three-dimensionally arrayed channel networks |
RU2278612C2 (en) * | 2000-07-14 | 2006-06-27 | Лайфскен, Инк. | Immune sensor |
US6726818B2 (en) * | 2000-07-21 | 2004-04-27 | I-Sens, Inc. | Biosensors with porous chromatographic membranes |
JP2002195997A (en) * | 2000-09-29 | 2002-07-10 | Toshiba Corp | Sensor for detecting nucleic acid |
GB0028647D0 (en) * | 2000-11-24 | 2001-01-10 | Nextgen Sciences Ltd | Apparatus for chemical assays |
GB0030929D0 (en) * | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
JPWO2002066969A1 (en) * | 2001-02-19 | 2004-06-24 | 協和メデックス株式会社 | Charged component detection device, method of using the same, and detection panel |
US6949377B2 (en) * | 2001-03-05 | 2005-09-27 | Ho Winston Z | Chemiluminescence-based microfluidic biochip |
JP2002286727A (en) * | 2001-03-28 | 2002-10-03 | Canon Inc | Probe carrier, method of manufacturing probe carrier, and device being used in it |
US6475306B1 (en) * | 2001-04-10 | 2002-11-05 | Nippon Steel Corporation | Hot rolled steel wire rod or bar for machine structural use and method for producing the same |
DE60229476D1 (en) * | 2001-05-29 | 2008-12-04 | Matsushita Electric Ind Co Ltd | Biosensor |
JP2002365294A (en) * | 2001-06-08 | 2002-12-18 | Fuji Photo Film Co Ltd | Nucleic acid sample detecting implement and electrochemical detecting method |
US7419821B2 (en) * | 2002-03-05 | 2008-09-02 | I-Stat Corporation | Apparatus and methods for analyte measurement and immunoassay |
US6689258B1 (en) * | 2002-04-30 | 2004-02-10 | Advanced Micro Devices, Inc. | Electrochemically generated reactants for chemical mechanical planarization |
US6801041B2 (en) * | 2002-05-14 | 2004-10-05 | Abbott Laboratories | Sensor having electrode for determining the rate of flow of a fluid |
US7041469B2 (en) * | 2002-10-10 | 2006-05-09 | Quidel Corporation | Assays for trichomonal and other hydrolases |
CA2772050C (en) | 2002-12-26 | 2016-09-06 | Meso Scale Technologies, Llc. | Assay cartridges and methods of using the same |
JP4685611B2 (en) * | 2005-12-02 | 2011-05-18 | 株式会社エンプラス | Microfluidic device |
WO2010147942A1 (en) * | 2009-06-16 | 2010-12-23 | Massachusetts Institute Of Technology | Multiphase non-linear electrokinetic devices |
-
2003
- 2003-12-23 CA CA2772050A patent/CA2772050C/en not_active Expired - Lifetime
- 2003-12-23 AU AU2003302263A patent/AU2003302263A1/en not_active Abandoned
- 2003-12-23 CA CA3122193A patent/CA3122193A1/en not_active Expired - Lifetime
- 2003-12-23 EP EP03810079.8A patent/EP1583950B1/en not_active Expired - Lifetime
- 2003-12-23 CA CA3171720A patent/CA3171720C/en not_active Expired - Lifetime
- 2003-12-23 US US10/744,726 patent/US7497997B2/en active Active
- 2003-12-23 CA CA2941139A patent/CA2941139C/en not_active Expired - Lifetime
- 2003-12-23 CN CN2003801099993A patent/CN101098956B/en not_active Expired - Lifetime
- 2003-12-23 WO PCT/US2003/041241 patent/WO2004061418A2/en active Search and Examination
- 2003-12-23 CA CA2511389A patent/CA2511389C/en not_active Expired - Lifetime
- 2003-12-23 JP JP2004565694A patent/JP4764010B2/en not_active Expired - Lifetime
- 2003-12-23 EP EP13198399.1A patent/EP2711415B1/en not_active Expired - Lifetime
- 2003-12-23 CN CN201210048043.8A patent/CN102620959B/en not_active Expired - Lifetime
-
2008
- 2008-06-26 HK HK08107106.8A patent/HK1117189A1/en not_active IP Right Cessation
- 2008-10-02 US US12/244,119 patent/US8641986B2/en active Active
- 2008-10-02 US US12/244,133 patent/US8012745B2/en active Active
-
2010
- 2010-05-17 JP JP2010113192A patent/JP5127878B2/en not_active Expired - Lifetime
-
2011
- 2011-01-04 AU AU2011200010A patent/AU2011200010B2/en not_active Expired
- 2011-03-31 JP JP2011077363A patent/JP2011169908A/en active Pending
- 2011-06-17 JP JP2011135339A patent/JP5367019B2/en not_active Expired - Lifetime
- 2011-08-30 US US13/221,427 patent/US8852922B2/en active Active
-
2014
- 2014-02-03 US US14/170,721 patent/US9404881B2/en not_active Expired - Lifetime
- 2014-09-05 US US14/478,197 patent/US9921166B2/en not_active Expired - Lifetime
-
2016
- 2016-07-28 US US15/222,674 patent/US10935547B2/en not_active Expired - Lifetime
-
2018
- 2018-02-16 US US15/898,283 patent/US20180172595A1/en not_active Abandoned
-
2020
- 2020-07-29 US US16/942,130 patent/US20200355616A1/en active Pending
- 2020-11-05 US US17/090,367 patent/US20210055287A1/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4014206A (en) * | 1975-03-31 | 1977-03-29 | Akron City Hospital | Apparatus and method for monitoring air emboli during extracorporeal circulation |
US5399256A (en) * | 1994-01-07 | 1995-03-21 | Bioanalytical Systems, Inc. | Electrochemical detector cell |
US6403367B1 (en) * | 1994-07-07 | 2002-06-11 | Nanogen, Inc. | Integrated portable biological detection system |
US6673533B1 (en) * | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
US6440662B1 (en) * | 1995-12-01 | 2002-08-27 | Innogenetics N.V. | Impedimetric detection system and method of production thereof |
US6264825B1 (en) * | 1998-06-23 | 2001-07-24 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2004061418A3 (en) | Assay cartridges and methods of using the same | |
SG145758A1 (en) | Apparatus for processing a fluid sample | |
WO2011071772A3 (en) | Assay cartridges and methods of using the same | |
WO2003064993A3 (en) | Methods and materials for detecting genetic material | |
WO2001068238A3 (en) | Microfluidic analysis cartridge | |
WO2004011144A3 (en) | Transparent polymer support for electrophoresis and electrochromatography and related methods | |
ATE302263T1 (en) | PLANT FOR BREAKING CELLS | |
WO2007044091A3 (en) | Analysis using microfluidic partitioning devices | |
RU2014145341A (en) | METHOD FOR CREATING AN ANALYTICAL PRODUCTS STORE | |
WO2007005854A3 (en) | Modular sample processing apparatus kits and modules | |
IL179829A (en) | Laser radiation desorption device for manipulating a liquid sample in the form of individual drops, thereby making it possible to carry out the chemical and biological treatment thereof | |
WO2004068087A3 (en) | Sensitive sensing based on optical nonlinear wave mixing | |
WO2006116616A3 (en) | Systems and methods for multiple analyte detection | |
WO2005003723A3 (en) | Method for uniform application of fluid into a reactive reagent area | |
WO2004067162A3 (en) | Apparatus for microfluidic processing and reading of biochip arrays | |
EP1619500A4 (en) | Biochip and biochip kit, and method of producing the same and method of using the same | |
ATE355529T1 (en) | SAMPLE ANALYZER AND DEVICE FOR DETECTING NUCLEIC ACIDS | |
WO2005029073A8 (en) | Chromatographic assay device and methods | |
WO2006036738A3 (en) | Photometric analysis | |
WO2007021756A3 (en) | Methods for characterizing biological molecule modulators | |
EP1234053A4 (en) | Apparatus and method for assaying coagulation in fluid samples | |
WO2007086900A3 (en) | Stilbazium research assays | |
GB2423266B (en) | An analyte assay structure in microfluidic chip for quantitative analysis and method for using the same | |
WO2005024384A3 (en) | Devices and methods for separating phospholipids from biological samples | |
WO2006041938A3 (en) | Micropatterned plate with micro-pallets for addressable biochemical analysis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CU CZ DE DK EE ES FI GB GD GE GH HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2511389 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2003302263 Country of ref document: AU Ref document number: 2004565694 Country of ref document: JP |
|
REEP | Request for entry into the european phase |
Ref document number: 2003810079 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2003810079 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1688/CHENP/2005 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 20038A99993 Country of ref document: CN |
|
WWP | Wipo information: published in national office |
Ref document number: 2003810079 Country of ref document: EP |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) |