WO2004056411A2 - Flexible piston rod - Google Patents

Flexible piston rod Download PDF

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Publication number
WO2004056411A2
WO2004056411A2 PCT/DK2003/000915 DK0300915W WO2004056411A2 WO 2004056411 A2 WO2004056411 A2 WO 2004056411A2 DK 0300915 W DK0300915 W DK 0300915W WO 2004056411 A2 WO2004056411 A2 WO 2004056411A2
Authority
WO
WIPO (PCT)
Prior art keywords
piston rod
elements
strip
top surface
actuator
Prior art date
Application number
PCT/DK2003/000915
Other languages
French (fr)
Other versions
WO2004056411A3 (en
Inventor
Morten MERNØE
Original Assignee
M 2 Medical A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M 2 Medical A/S filed Critical M 2 Medical A/S
Priority to EP03767479A priority Critical patent/EP1583573B1/en
Priority to JP2004561090A priority patent/JP2006511262A/en
Priority to DE60336080T priority patent/DE60336080D1/en
Priority to AU2003291963A priority patent/AU2003291963A1/en
Priority to AT03767479T priority patent/ATE498421T1/en
Priority to DK03767479.3T priority patent/DK1583573T3/en
Publication of WO2004056411A2 publication Critical patent/WO2004056411A2/en
Publication of WO2004056411A3 publication Critical patent/WO2004056411A3/en
Priority to US11/158,277 priority patent/US7220248B2/en
Priority to US11/697,168 priority patent/US7625358B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0266Shape memory materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546Front-loading type injectors

Definitions

  • the present invention relates to a flexible piston rod, particularly for use in medicine dispensing devices.
  • An object of the present invention is to provide a flexible piston rod that is simple to manufacture and operate and requires relatively small displacement forces.
  • the piston rod comprising a row of elements each having a top surface and a bottom surface as well as a lateral surface, the top surface of one element being connected to the bottom surface of the adjacent element by a hinge means located and adapted to allow the two adjacent elements to pivot from a first position where at least a portion of a top surface of one element abuts a corresponding portion of the bottom surface of the adjacent element, said first position corresponding to a rectilinear, relatively stiff configuration of the piston rod, to a second position wherein said top surface of one element is spaced from said bottom surface of the adjacent element corresponding to a curved configuration of said flexible piston rod.
  • said lateral surface has first and a second mutually opposed circular cylindrical surface portions incorporating a screw thread for meshing with a corresponding screw thread of an actuator for displacing the piston rod in the longitudinal direction thereof.
  • At least one surface portion disposed between said first and second surface portion is plane so as to allow co-operation with means to prevent rotation of the piston rod around the longitudinal axis thereof when said screw threads on the lateral surface of said elements are engaged by said actuator screw threads.
  • said portions of said top and bottom surfaces are spaced from said hinge.
  • said portions of said top and bottom surfaces are spaced from said hinge.
  • said elements and said hinges form an integrally moulded piston rod moulded in one piece from a mouldable material, preferably a plastic material such as Nylon or POM.
  • the present invention relates to a flexible piston rod comprising a strip of relatively stiff and resilient material such as steel having in the relaxed state an arcuate cross section taken transversely to the longitudinal direction of said strip, a longitudinal row of evenly space apertures being provided along the length of said strip for receiving projection of an actuator for displacing said strip in the longitudinal direction thereof, and preferably the major portion of the said strip is rolled into a roll when the piston rod is in its least extended condition.
  • Fig. 1 is a schematic view of a first embodiment of a flexible piston rod according to the invention
  • Figs. 2-4 are schematic enlarged scale views of the hinge mechanism of the flexible piston rod according to Fig. 1 ,
  • Figs. 5-8 are schematic enlarged scale views from different angles of an element of the flexible piston rod of Fig. 1 ,
  • Fig 9 is a schematic isometric view of a medicine dispensing device incorporating a flexible piston rod as shown in Fig. 1 , and
  • Fig. 10 is a schematic isometric view of second embodiment of a flexible piston rod applied to a medicine dispensing device.
  • a piston 1 is attached to one end of a flexible piston rod 2 constituted by a series of elements 3 interconnected by hinges 4.
  • the elements 3 are integral with each other by means of the hinges 4 which allow mutually adjacent elements to pivot relative to one another from the position abutting one another shown in Fig. 2 wherein the elements 3 together form a rectilinear piston rod with abutment surfaces 5 and hinges 4 affording rigidity and thus rendering the piston rod 2 capable of exerting a pressure on the piston 1 without deflecting laterally, to the position shown in Fig. 4 wherein the elements 3 are pivoted way from one another so as to allow the curvature of the piston rod 2.
  • the material of the flexible piston rod 2 may any suitable mouldable material, but it is preferred that it be a plastic material such as Nylon or POM.
  • the elements, hinges and piston are moulded in one piece in a single moulding operation which reduces the manufacturing cost considerably.
  • Each element 3 is provided with exterior threads 6 on two opposed portions 7 and 8 of the elements having a circular cylindrical configuration.
  • At least the side 9 of the elements 3 coinciding with the hinges 4 is flat to allow practical moulding of the hinge.
  • a further function of the flat side 9 or preferably two opposed flat sides 9 and 10 is to allow preventing rotation of the piston rod 2 around its axis when being axially displaced by the threads of an actuator meshing with the threads 6, see for instance Fig. 9.
  • the flexible piston rod 2 is shown in use for dispensing insulin from a carpule 11 shown before being placed in operational position for greater clarity and having a not shown internal piston for being abutted and displaced by the piston 1.
  • the piston rod 2 is arranged for movement between two guide walls 12 and 13 in a housing 14 of the device.
  • the piston 1 abuts the not shown displaceable wall or piston of the carpule 11 such that axial displacement of the piston 1 will press insulin out of the carpule 11 into a not shown needle for injection into a patient.
  • a gear 15 mounted for rotation in the housing 14 is provided with a central aperture through which the elements 3 of the piston extend.
  • the internal aperture is provided with a not shown screw thread meshing with the screw thread 6of the piston elements 3 such that rotation of the gear 15 entails displacement of the piston 1 into the carpule 11.
  • the gear 15 is rotated by a shape memory alloy actuator comprising a wire 16 of a shape memory alloy such as Nitinol, one end of which is attached to a rivet 17 and the other end of which is attached to the free end of an actuator spring rod 18.
  • a shape memory alloy actuator comprising a wire 16 of a shape memory alloy such as Nitinol, one end of which is attached to a rivet 17 and the other end of which is attached to the free end of an actuator spring rod 18.
  • the free end of the actuator spring rod 18 is located such that it meshes with the teeth of the gear 15 and is biased by the spring force of the rod to exert a spring force in the tangential direction and in the radial direction.
  • a pawl spring rod 19 is located such that the end thereof meshes with the teeth of the gear 15 and is biased to exert a spring force in the radial direction. This end of the pawl spring rod 19 is constrained to substantially only move in the radial direction by two not shown stop pins.
  • a not shown battery supplies power to the ends of the nitinol wire 16 for heating it so as to cause it to contract.
  • Rotation of the gear 15 is brought about by alternatingly heating and cooling the nitinol wire 16 so that it contracts and cocks the spring rod 18 while the pawl spring rod holds the gear 13 against rotation and thereafter expands and allows the spring rod to turn the gear and advance the piston rod 2.
  • the flat surface 9 and 10 of the elements 3 abut the flat surfaces of the guide walls 12 and 13 and prevent the piston rod 2 from rotating around the longitudinal axis 20 thereof under the influence of the rotating gear 15.
  • the flexible piston rod 2 could also be displaced by means of another actuator, for instance a worm gear:
  • a carpule 11 identical to the one described in connection with Fig. 9 is located adjacent an actuator generally referenced by the numeral 21 with a piston 22 of the actuator abutting the not visible piston of the carpule.
  • the piston 22 is attached to the end of a steel strip 23 having an arcuate cross section taken at right angles to the longitudinal direction of the strip 23.
  • This arcuate shape entails a rigidity of the strip 23 against lateral deflection such that the strip can transmit pressure forces to the piston 22 without collapsing because of lateral deflection.
  • a row of evenly spaced elongate apertures 24 are provided in the strip 23 for receiving ribs 25 of a roller 26 having a gear 27 meshing with a worm gear 28.
  • the worm gear is actuated by an actuator that may be similar to the shape memory alloy actuator of Fig 9.

Abstract

A flexible piston rod 2, particularly for use in medicine dispensing devices, comprising a piston 1 and a row of elements 3 each having a top surface and a bottom surface as well as a lateral surface, the top surface of one element being connected to the bottom surface of the adjacent element by a hinge means 4 adapted to allow the two adjacent elements to pivot from a first position where at least a portion of a top surface of one element abuts a corresponding portion of the bottom surface of the adjacent element, the first position corresponding to a rectilinear, relatively stiff configuration of the piston rod2, to a second position wherein the top surface of one element is spaced from the bottom surface of he adjacent element corresponding to a curved configuration of the piston rod, the lateral surface of each element having a first and a second mutually opposed circular cylindrical surface portions incorporating a screw thread 6 for meshing with a corresponding screw thread of an actuator for displacing the piston rod in the longitudinal direction thereof.

Description

FLEXIBLE PISTON ROD
The present invention relates to a flexible piston rod, particularly for use in medicine dispensing devices.
So as to render devices and applications where a piston rod is to linearly displace an object more compact it is desirable to avoid the space requirements necessary for allowing a rigid rectilinear piston rod to travel the entire displacement length along its axis. Several flexible piston rods have been conceived embodying a coil spring supported by an internal curved mandrel or guide rod or various elements collaborating with one another. All the known flexible piston rods are either too complicated or require relatively large forces to be displaced.
An object of the present invention is to provide a flexible piston rod that is simple to manufacture and operate and requires relatively small displacement forces.
According to the invention this object is achieved by the piston rod comprising a row of elements each having a top surface and a bottom surface as well as a lateral surface, the top surface of one element being connected to the bottom surface of the adjacent element by a hinge means located and adapted to allow the two adjacent elements to pivot from a first position where at least a portion of a top surface of one element abuts a corresponding portion of the bottom surface of the adjacent element, said first position corresponding to a rectilinear, relatively stiff configuration of the piston rod, to a second position wherein said top surface of one element is spaced from said bottom surface of the adjacent element corresponding to a curved configuration of said flexible piston rod.
In the currently preferred embodiment of a flexible piston rod according to the invention, said lateral surface has first and a second mutually opposed circular cylindrical surface portions incorporating a screw thread for meshing with a corresponding screw thread of an actuator for displacing the piston rod in the longitudinal direction thereof. Hereby a simple displacement mechanism which is self supporting and self centering is achieved.
Preferably, at least one surface portion disposed between said first and second surface portion is plane so as to allow co-operation with means to prevent rotation of the piston rod around the longitudinal axis thereof when said screw threads on the lateral surface of said elements are engaged by said actuator screw threads.
Preferably, said portions of said top and bottom surfaces are spaced from said hinge. Hereby a particularly stable rectilinear configuration of the piston rod is achieved.
Advantageously, said elements and said hinges form an integrally moulded piston rod moulded in one piece from a mouldable material, preferably a plastic material such as Nylon or POM.
In another aspect, the present invention relates to a flexible piston rod comprising a strip of relatively stiff and resilient material such as steel having in the relaxed state an arcuate cross section taken transversely to the longitudinal direction of said strip, a longitudinal row of evenly space apertures being provided along the length of said strip for receiving projection of an actuator for displacing said strip in the longitudinal direction thereof, and preferably the major portion of the said strip is rolled into a roll when the piston rod is in its least extended condition.
In the following, the invention will be described and explained more in detail with reference to embodiments thereof shown, solely by way of example, in the accompanying drawings, where
Fig. 1 is a schematic view of a first embodiment of a flexible piston rod according to the invention, Figs. 2-4 are schematic enlarged scale views of the hinge mechanism of the flexible piston rod according to Fig. 1 ,
Figs. 5-8 are schematic enlarged scale views from different angles of an element of the flexible piston rod of Fig. 1 ,
Fig 9 is a schematic isometric view of a medicine dispensing device incorporating a flexible piston rod as shown in Fig. 1 , and
Fig. 10 is a schematic isometric view of second embodiment of a flexible piston rod applied to a medicine dispensing device.
Referring now to Figs. 1-8, a piston 1 is attached to one end of a flexible piston rod 2 constituted by a series of elements 3 interconnected by hinges 4. The elements 3 are integral with each other by means of the hinges 4 which allow mutually adjacent elements to pivot relative to one another from the position abutting one another shown in Fig. 2 wherein the elements 3 together form a rectilinear piston rod with abutment surfaces 5 and hinges 4 affording rigidity and thus rendering the piston rod 2 capable of exerting a pressure on the piston 1 without deflecting laterally, to the position shown in Fig. 4 wherein the elements 3 are pivoted way from one another so as to allow the curvature of the piston rod 2.
This ability to curve allows the compact configuration of any device utilizing the flexible piston rod 2 to linearly displace an object because the initially major part of the piston rod may extend along the intended path of travel of the piston 1 during such displacement of said object, see Fig. 9 and the corresponding explanation.
The material of the flexible piston rod 2 may any suitable mouldable material, but it is preferred that it be a plastic material such as Nylon or POM. The elements, hinges and piston are moulded in one piece in a single moulding operation which reduces the manufacturing cost considerably. Each element 3 is provided with exterior threads 6 on two opposed portions 7 and 8 of the elements having a circular cylindrical configuration. At least the side 9 of the elements 3 coinciding with the hinges 4 is flat to allow practical moulding of the hinge. A further function of the flat side 9 or preferably two opposed flat sides 9 and 10 is to allow preventing rotation of the piston rod 2 around its axis when being axially displaced by the threads of an actuator meshing with the threads 6, see for instance Fig. 9.
Referring now to Fig. 9, the flexible piston rod 2 is shown in use for dispensing insulin from a carpule 11 shown before being placed in operational position for greater clarity and having a not shown internal piston for being abutted and displaced by the piston 1. The piston rod 2 is arranged for movement between two guide walls 12 and 13 in a housing 14 of the device. The piston 1 abuts the not shown displaceable wall or piston of the carpule 11 such that axial displacement of the piston 1 will press insulin out of the carpule 11 into a not shown needle for injection into a patient.
A gear 15 mounted for rotation in the housing 14 is provided with a central aperture through which the elements 3 of the piston extend. The internal aperture is provided with a not shown screw thread meshing with the screw thread 6of the piston elements 3 such that rotation of the gear 15 entails displacement of the piston 1 into the carpule 11.
The gear 15 is rotated by a shape memory alloy actuator comprising a wire 16 of a shape memory alloy such as Nitinol, one end of which is attached to a rivet 17 and the other end of which is attached to the free end of an actuator spring rod 18.
The free end of the actuator spring rod 18 is located such that it meshes with the teeth of the gear 15 and is biased by the spring force of the rod to exert a spring force in the tangential direction and in the radial direction. A pawl spring rod 19 is located such that the end thereof meshes with the teeth of the gear 15 and is biased to exert a spring force in the radial direction. This end of the pawl spring rod 19 is constrained to substantially only move in the radial direction by two not shown stop pins.
A not shown battery supplies power to the ends of the nitinol wire 16 for heating it so as to cause it to contract.
Rotation of the gear 15 is brought about by alternatingly heating and cooling the nitinol wire 16 so that it contracts and cocks the spring rod 18 while the pawl spring rod holds the gear 13 against rotation and thereafter expands and allows the spring rod to turn the gear and advance the piston rod 2.
The flat surface 9 and 10 of the elements 3 abut the flat surfaces of the guide walls 12 and 13 and prevent the piston rod 2 from rotating around the longitudinal axis 20 thereof under the influence of the rotating gear 15.
The flexible piston rod 2 could also be displaced by means of another actuator, for instance a worm gear:
Referring now to Fig.1 , a carpule 11 identical to the one described in connection with Fig. 9 is located adjacent an actuator generally referenced by the numeral 21 with a piston 22 of the actuator abutting the not visible piston of the carpule.
The piston 22 is attached to the end of a steel strip 23 having an arcuate cross section taken at right angles to the longitudinal direction of the strip 23. This arcuate shape entails a rigidity of the strip 23 against lateral deflection such that the strip can transmit pressure forces to the piston 22 without collapsing because of lateral deflection.
A row of evenly spaced elongate apertures 24 are provided in the strip 23 for receiving ribs 25 of a roller 26 having a gear 27 meshing with a worm gear 28. The worm gear is actuated by an actuator that may be similar to the shape memory alloy actuator of Fig 9.
By rotating the worm gear 28 the gear 27 and roller 26 are rotated whereby the ribs 25 received in the slits 24 unwind the strip 23 from the roll and displace it into the carpule 11 whereby the piston 22 displaces the carpule piston and dispenses the insulin from the carpule 11 that is located in the dispensing device in the same manner as the carpule 11 of Fig. 9.

Claims

Claims
1. A flexible piston rod, particularly for use in medicine dispensing devices, comprising a row of elements each having a top surface and a bottom surface as well as a lateral surface, the top surface of one element being connected to the bottom surface of the adjacent element by a hinge means located and adapted to allow the two adjacent elements to pivot from a first position where at least a portion of a top surface of one element abuts a corresponding portion of the bottom surface of the adjacent element, said first position corresponding to a rectilinear, relatively stiff configuration of the piston rod, to a second position wherein said top surface of one element is spaced from said bottom surface of the adjacent element corresponding to a curved configuration of said flexible piston rod.
2. A piston rod according to claim 1 , wherein said lateral surface has a first and a second mutually opposed circular cylindrical surface portions incorporating a screw thread for meshing with a corresponding screw thread of an actuator for displacing the piston rod in the longitudinal direction thereof.
3. A piston rod according to claim 2, wherein at least one surface portion disposed between said first and second surface portion is plane so as to allow co-operation with means to prevent rotation of the piston rod around the longitudinal axis thereof when said screw threads on the lateral surface of said elements are engaged by said actuator screw threads.
4. A piston rod according to any of the preceding claims, wherein said portions of said top and bottom surfaces are spaced from said hinge.
5. A piston rod according to any of the preceding claims, wherein said elements and said hinges form an integrally moulded piston rod moulded in one piece from a mouldable material, preferably a plastic material such as Nylon or POM.
6. A flexible piston rod comprising a strip of relatively stiff and resilient material such as steel having in the relaxed state an arcuate cross section taken transversely to the longitudinal direction of said strip, a longitudinal row of evenly space apertures being provided along the length of said strip for receiving projection of an actuator for displacing said strip in the longitudinal direction thereof.
7. A piston rod according to claim 7 wherein the major portion of the said strip is rolled into a roll when the piston rod is in its least extended condition.
PCT/DK2003/000915 2002-12-23 2003-12-19 Flexible piston rod WO2004056411A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP03767479A EP1583573B1 (en) 2002-12-23 2003-12-19 Flexible piston rod
JP2004561090A JP2006511262A (en) 2002-12-23 2003-12-19 Flexible piston rod
DE60336080T DE60336080D1 (en) 2002-12-23 2003-12-19 BENDING PISTON ROD
AU2003291963A AU2003291963A1 (en) 2002-12-23 2003-12-19 Flexible piston rod
AT03767479T ATE498421T1 (en) 2002-12-23 2003-12-19 FLEXIBLE PISTON ROD
DK03767479.3T DK1583573T3 (en) 2002-12-23 2003-12-19 Flexible piston rod
US11/158,277 US7220248B2 (en) 2002-12-23 2005-06-21 Flexible piston rod
US11/697,168 US7625358B2 (en) 2002-12-23 2007-04-05 Flexible piston rod

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200202007 2002-12-23
DKPA200202007 2002-12-23

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/158,277 Continuation US7220248B2 (en) 2002-12-23 2005-06-21 Flexible piston rod

Publications (2)

Publication Number Publication Date
WO2004056411A2 true WO2004056411A2 (en) 2004-07-08
WO2004056411A3 WO2004056411A3 (en) 2004-08-12

Family

ID=32668637

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2003/000915 WO2004056411A2 (en) 2002-12-23 2003-12-19 Flexible piston rod

Country Status (9)

Country Link
US (2) US7220248B2 (en)
EP (1) EP1583573B1 (en)
JP (1) JP2006511262A (en)
CN (1) CN1732027A (en)
AT (1) ATE498421T1 (en)
AU (1) AU2003291963A1 (en)
DE (1) DE60336080D1 (en)
DK (1) DK1583573T3 (en)
WO (1) WO2004056411A2 (en)

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WO2008152623A1 (en) * 2007-06-11 2008-12-18 Medingo Ltd. Portable infusion device with reduced level of operational noise
EP3260151A1 (en) 2016-06-23 2017-12-27 TecPharma Licensing AG A needle insertion and retraction mechanism for a medication delivery device
EP3260149A1 (en) 2016-06-23 2017-12-27 TecPharma Licensing AG A method for fixation of a cartridge in an injection device
EP3260146A1 (en) 2016-06-23 2017-12-27 TecPharma Licensing AG A coupling mechanism for a medication delivery device
EP3260147A1 (en) 2016-06-23 2017-12-27 TecPharma Licensing AG A segmented piston rod for a medication delivery device
EP3348284A2 (en) 2017-01-12 2018-07-18 Tecpharma Licensing AG A method for sterilization of a fluid path for an injection device
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WO2018130944A1 (en) 2017-01-12 2018-07-19 Tecpharma Licensing Ag A method for sterilization of a fluid path for an injection device
EP3348284A2 (en) 2017-01-12 2018-07-18 Tecpharma Licensing AG A method for sterilization of a fluid path for an injection device
WO2018189462A1 (en) 2017-04-10 2018-10-18 Aptar France Sas Automatic fluid product injection device
FR3064920A1 (en) * 2017-04-10 2018-10-12 Aptar France Sas AUTOMATIC FLUID INJECTION DEVICE.
US11229739B2 (en) 2017-04-10 2022-01-25 Aptar France Sas Automatic fluid product injection device

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WO2004056411A3 (en) 2004-08-12
CN1732027A (en) 2006-02-08
US7220248B2 (en) 2007-05-22
EP1583573A2 (en) 2005-10-12
AU2003291963A1 (en) 2004-07-14
DE60336080D1 (en) 2011-03-31
US20050251097A1 (en) 2005-11-10
AU2003291963A8 (en) 2004-07-14
US20070203459A1 (en) 2007-08-30
US7625358B2 (en) 2009-12-01
DK1583573T3 (en) 2011-05-09
EP1583573B1 (en) 2011-02-16
ATE498421T1 (en) 2011-03-15
JP2006511262A (en) 2006-04-06

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