WO2004039434A3 - Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe - Google Patents

Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe Download PDF

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Publication number
WO2004039434A3
WO2004039434A3 PCT/US2003/034842 US0334842W WO2004039434A3 WO 2004039434 A3 WO2004039434 A3 WO 2004039434A3 US 0334842 W US0334842 W US 0334842W WO 2004039434 A3 WO2004039434 A3 WO 2004039434A3
Authority
WO
WIPO (PCT)
Prior art keywords
prefilled syringe
syringe
sequential delivery
substances stored
chamber
Prior art date
Application number
PCT/US2003/034842
Other languages
French (fr)
Other versions
WO2004039434B1 (en
WO2004039434A2 (en
Inventor
Kyongtae T Bae
Original Assignee
Kyongtae T Bae
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyongtae T Bae filed Critical Kyongtae T Bae
Priority to AU2003290566A priority Critical patent/AU2003290566A1/en
Publication of WO2004039434A2 publication Critical patent/WO2004039434A2/en
Publication of WO2004039434A3 publication Critical patent/WO2004039434A3/en
Publication of WO2004039434B1 publication Critical patent/WO2004039434B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A syringe (12) capable of injecting two substances (142, 152) sequentially is provided. The syringe (120) has first (140) and second (150) chambers capable of separately storing a contents of the syringe (120) before and during injection. The syringe (120) has an outlet (122) through which the contents stored in the first (140) and second chamber (150) flow during injection. After completing injection of the contents stored in the first chamber (140), the second chamber (150) is aligned with the outlet (122) to allow injection of the contents stored in the second chamber (150).
PCT/US2003/034842 2002-10-31 2003-10-30 Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe WO2004039434A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003290566A AU2003290566A1 (en) 2002-10-31 2003-10-30 Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/285,001 US6866653B2 (en) 2002-10-31 2002-10-31 Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe
US10/285,001 2002-10-31

Publications (3)

Publication Number Publication Date
WO2004039434A2 WO2004039434A2 (en) 2004-05-13
WO2004039434A3 true WO2004039434A3 (en) 2004-09-23
WO2004039434B1 WO2004039434B1 (en) 2004-11-11

Family

ID=32228811

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/034842 WO2004039434A2 (en) 2002-10-31 2003-10-30 Method and apparatus for sequential delivery of multiple injectable substances stored in a prefilled syringe

Country Status (3)

Country Link
US (1) US6866653B2 (en)
AU (1) AU2003290566A1 (en)
WO (1) WO2004039434A2 (en)

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WO2004049777A2 (en) * 2002-12-04 2004-06-17 Washington University Method and apparatus for automated detection of target structures from medical images using a 3d morphological matching algorithm
US8777889B2 (en) * 2004-06-15 2014-07-15 Ceramatec, Inc. Apparatus and method for administering a therapeutic agent into tissue
CA2944753A1 (en) 2004-02-02 2005-08-11 Bimeda Research & Development Limited Sequential delivery injector device
AR054639A1 (en) 2004-02-02 2007-07-11 Bimeda Res & Dev Ltd A METHOD AND DEVICE
US7101354B2 (en) * 2004-05-03 2006-09-05 Infusive Technologies, Llc Mixing syringe with and without flush
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EP2990073B1 (en) 2004-11-24 2018-05-02 Bayer Healthcare LLC Devices and systems for fluid delivery
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US8529517B2 (en) * 2005-05-02 2013-09-10 Shi Zi Technology, Ltd. Autoflush syringe
US8075533B2 (en) * 2005-05-02 2011-12-13 Preventiv, Inc. Autoflush syringe
US8936577B2 (en) 2005-05-02 2015-01-20 Shi Zi Technology, Ltd. Methods and devices for autoflush syringes
US7981908B2 (en) * 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
CN101175519A (en) * 2005-05-16 2008-05-07 马林克罗特公司 Multi-stage syringe and methods of using the same
US8041409B2 (en) * 2005-09-08 2011-10-18 Carestream Health, Inc. Method and apparatus for multi-modal imaging
JP4682850B2 (en) * 2006-01-12 2011-05-11 ニプロ株式会社 Prefilled syringe
US8220985B2 (en) * 2006-02-10 2012-07-17 Dow Global Technologies Llc Retractable pin mixing sample forming device
EP3376504A1 (en) 2006-12-29 2018-09-19 Bayer Healthcare, LLC Patient-based parameter generation systems for medical injection procedures
JP2008259704A (en) * 2007-04-12 2008-10-30 Hisamitsu Pharmaceut Co Inc Prefilled syringe
WO2008137578A1 (en) * 2007-05-01 2008-11-13 Geisinger Clinic Devices and methods for fluid administration
US20080294115A1 (en) * 2007-05-22 2008-11-27 Chen Raymond H Microscopic Tumor Injection Treatment
US20080294141A1 (en) * 2007-05-22 2008-11-27 Convergent Medical Solutions, Inc. Multiple robotic injections of immunosuppressive drugs based on scanned image
US20080294106A1 (en) * 2007-05-22 2008-11-27 Convergent Medical Solutions, Inc. Multiple robotic injections of anesthesia based on scanned image
US20080294107A1 (en) * 2007-05-22 2008-11-27 Convergent Medical Solutions, Inc. Multiple robotic injections of prenatal medications based on scanned image
US8428694B2 (en) * 2007-07-17 2013-04-23 Medrad, Inc. Methods for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
CA2639729A1 (en) * 2007-09-27 2009-03-27 Tyco Healthcare Group Lp Multiple stage fluid delivery device and method of use
CN101868274B (en) * 2007-11-22 2013-05-08 比奥维特罗姆上市公司 A method and device for the serial ejection of two fluids comprising a spacer
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US8315449B2 (en) * 2008-06-24 2012-11-20 Medrad, Inc. Identification of regions of interest and extraction of time value curves in imaging procedures
US8142403B2 (en) * 2008-06-30 2012-03-27 Tyco Healthcare Group Lp Syringe assembly with plunger having a secondary dispensing reservoir
US8152778B2 (en) * 2008-09-30 2012-04-10 Tyco Healthcare Group Lp Device for interfacing with standard luer lock syringes
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
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CA2873351C (en) 2012-05-14 2022-07-26 Bayer Medical Care Inc. Systems and methods for determination of pharmaceutical fluid injection protocols based on x-ray tube voltage
US9855385B2 (en) * 2013-03-13 2018-01-02 Bayer Healthcare Llc Multiple compartment syringe
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JP6514211B2 (en) 2013-09-16 2019-05-15 ゾエティス・サービシーズ・エルエルシー Assembly and related methods for continuous drug delivery
DE102015002234A1 (en) 2014-12-05 2016-06-09 Elm - Plastic Gmbh Injector for dispensing a liquid or pasty substance, in particular medicament
WO2017152036A1 (en) 2016-03-03 2017-09-08 Bayer Healthcare Llc System and method for improved fluid delivery in multi-fluid injector systems
CN106039480A (en) * 2016-08-04 2016-10-26 山东威高集团医用高分子制品股份有限公司 Pre-filled syringe for continuous treatment
CA3067740A1 (en) 2017-08-31 2019-03-07 Bayer Healthcare Llc Method for drive member position and fluid injection system mechanical calibration
US11141535B2 (en) 2017-08-31 2021-10-12 Bayer Healthcare Llc Fluid path impedance assessment for improving fluid delivery performance
WO2019046260A1 (en) 2017-08-31 2019-03-07 Bayer Healthcare Llc Method for dynamic pressure control in a fluid injector system
US11478581B2 (en) 2017-08-31 2022-10-25 Bayer Healthcare Llc Fluid injector system volume compensation system and method
WO2019046282A1 (en) 2017-08-31 2019-03-07 Bayer Healthcare Llc Injector pressure calibration system and method
FR3081299B1 (en) * 2018-05-23 2020-09-11 Oreal DEVICE FOR PREPARING A COSMETIC COMPOSTION, AND ASSOCIATED PROCESS
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Also Published As

Publication number Publication date
US20040097875A1 (en) 2004-05-20
US6866653B2 (en) 2005-03-15
AU2003290566A1 (en) 2004-05-25
WO2004039434B1 (en) 2004-11-11
AU2003290566A8 (en) 2004-05-25
WO2004039434A2 (en) 2004-05-13

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