WO2004026106A3 - Methods and apparatus for delivery of ocular implants - Google Patents

Methods and apparatus for delivery of ocular implants Download PDF

Info

Publication number
WO2004026106A3
WO2004026106A3 PCT/US2003/029518 US0329518W WO2004026106A3 WO 2004026106 A3 WO2004026106 A3 WO 2004026106A3 US 0329518 W US0329518 W US 0329518W WO 2004026106 A3 WO2004026106 A3 WO 2004026106A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
delivery
ocular implants
microimplant
microimplants
Prior art date
Application number
PCT/US2003/029518
Other languages
French (fr)
Other versions
WO2004026106A2 (en
Inventor
David Weber
Ingrid Kane
Mike Rehal
Robert L Lathrop Iii
Kenny Aptekarev
Jeffrey Etter
Original Assignee
Allergan Inc
David Weber
Ingrid Kane
Mike Rehal
Robert L Lathrop Iii
Kenny Aptekarev
Jeffrey Etter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/246,884 external-priority patent/US6899717B2/en
Priority to JP2004538247A priority Critical patent/JP3688287B1/en
Priority to PL413351A priority patent/PL227414B1/en
Priority to MXPA05002841A priority patent/MXPA05002841A/en
Priority to EP03754764A priority patent/EP1539065B1/en
Priority to BRPI0314288A priority patent/BRPI0314288B8/en
Priority to AU2003272575A priority patent/AU2003272575B2/en
Priority to ES03754764T priority patent/ES2400852T3/en
Application filed by Allergan Inc, David Weber, Ingrid Kane, Mike Rehal, Robert L Lathrop Iii, Kenny Aptekarev, Jeffrey Etter filed Critical Allergan Inc
Priority to CA002495621A priority patent/CA2495621C/en
Priority to NZ538380A priority patent/NZ538380A/en
Publication of WO2004026106A2 publication Critical patent/WO2004026106A2/en
Publication of WO2004026106A3 publication Critical patent/WO2004026106A3/en
Priority to NO20050934A priority patent/NO325505B1/en
Priority to HK05109456.3A priority patent/HK1077490A1/en
Priority to HK06102883A priority patent/HK1082902A1/en
Priority to NO20080055A priority patent/NO20080055L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/167—Instruments for inserting intraocular lenses into the eye with pushable plungers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Abstract

An apparatus and methods for delivering ocular implants or microimplants. The apparatus is ergonomically designed for ease of use, and a simple manual depression of an actuator produces proportional movement of a linkage causing the implant or microimplant to be ejected through a cannula disposed at the desired location in the eye. Small gauge cannulas are provided for self-sealing methods of delivery.
PCT/US2003/029518 2002-09-18 2003-09-18 Methods and apparatus for delivery of ocular implants WO2004026106A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
NZ538380A NZ538380A (en) 2002-09-18 2003-09-18 Methods and apparatus for delivery of ocular implants
ES03754764T ES2400852T3 (en) 2002-09-18 2003-09-18 Apparatus for the contribution of eye implants
MXPA05002841A MXPA05002841A (en) 2002-09-18 2003-09-18 Methods and apparatus for delivery of ocular implants.
EP03754764A EP1539065B1 (en) 2002-09-18 2003-09-18 Apparatus for delivery of ocular implants
CA002495621A CA2495621C (en) 2002-09-18 2003-09-18 Methods and apparatus for delivery of ocular implants
AU2003272575A AU2003272575B2 (en) 2002-09-18 2003-09-18 Methods and apparatus for delivery of ocular implants
PL413351A PL227414B1 (en) 2003-08-15 2003-09-18 Equipment for implanting an ophthalmological implant
JP2004538247A JP3688287B1 (en) 2002-09-18 2003-09-18 Device for delivering an ophthalmic implant
BRPI0314288A BRPI0314288B8 (en) 2002-09-18 2003-09-18 devices for sending eye implants
NO20050934A NO325505B1 (en) 2002-09-18 2005-02-21 Apparatus for implantation of an ocular implant
HK05109456.3A HK1077490A1 (en) 2002-09-18 2005-10-24 Apparatus for delivery of ocular implants
HK06102883A HK1082902A1 (en) 2002-09-18 2006-03-06 Apparatus for delivery of ocular implants
NO20080055A NO20080055L (en) 2002-09-18 2008-01-04 Methods and apparatus for delivering ocular implants

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10/246,884 2002-09-18
US10/246,884 US6899717B2 (en) 2002-09-18 2002-09-18 Methods and apparatus for delivery of ocular implants
US48669003P 2003-07-11 2003-07-11
US60/486,690 2003-07-11
US49557003P 2003-08-15 2003-08-15
US60/495,570 2003-08-15

Publications (2)

Publication Number Publication Date
WO2004026106A2 WO2004026106A2 (en) 2004-04-01
WO2004026106A3 true WO2004026106A3 (en) 2004-07-29

Family

ID=32034171

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/029518 WO2004026106A2 (en) 2002-09-18 2003-09-18 Methods and apparatus for delivery of ocular implants

Country Status (15)

Country Link
US (2) US7090681B2 (en)
EP (1) EP1539065B1 (en)
JP (1) JP3688287B1 (en)
KR (1) KR20050047118A (en)
CN (1) CN1301692C (en)
AU (1) AU2003272575B2 (en)
BR (1) BRPI0314288B8 (en)
CA (1) CA2495621C (en)
ES (1) ES2400852T3 (en)
HK (2) HK1077490A1 (en)
MX (1) MXPA05002841A (en)
NO (2) NO325505B1 (en)
PL (1) PL223153B1 (en)
TW (1) TWI282271B (en)
WO (1) WO2004026106A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8911768B2 (en) 2004-04-30 2014-12-16 Allergan, Inc. Methods for treating retinopathy with extended therapeutic effect
US9012437B2 (en) 2000-07-05 2015-04-21 Allergan, Inc. Implants and methods for treating inflammation-mediated conditions of the eye
US9192511B2 (en) 2003-01-09 2015-11-24 Allergan, Inc. Ocular implant made by a double extrusion process
US9283178B2 (en) 2000-11-29 2016-03-15 Allergan, Inc. Methods for treating edema in the eye and intraocular implants for use therefor

Families Citing this family (212)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808052D0 (en) 1998-04-17 1998-06-17 Secr Defence Implants for administering substances and methods of producing implants
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
CA2683224C (en) 2001-04-07 2014-12-02 Glaukos Corporation System and methods thereof for treatment of ocular disorders
US7331984B2 (en) 2001-08-28 2008-02-19 Glaukos Corporation Glaucoma stent for treating glaucoma and methods of use
US7468065B2 (en) * 2002-09-18 2008-12-23 Allergan, Inc. Apparatus for delivery of ocular implants
US20040225250A1 (en) 2003-05-05 2004-11-11 Michael Yablonski Internal shunt and method for treating glaucoma
US7291125B2 (en) 2003-11-14 2007-11-06 Transcend Medical, Inc. Ocular pressure regulation
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US8685435B2 (en) 2004-04-30 2014-04-01 Allergan, Inc. Extended release biodegradable ocular implants
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US20060052796A1 (en) * 2004-09-08 2006-03-09 Edward Perez Combined epithelial delaminator and inserter
EP1666085A1 (en) * 2004-12-01 2006-06-07 Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS Injection device for a solid implant
EP1666084A1 (en) * 2004-12-01 2006-06-07 Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS Injection device for a pharmaceutical active ingredient
ES2550429T3 (en) * 2004-12-01 2015-11-06 Ipsen Pharma Device for retroinjection of an implant
FR2881043B1 (en) * 2005-01-21 2007-04-27 Corneal Ind Sa FLEXIBLE INTRAOCULAR IMPLANT INJECTOR
ES2685795T3 (en) 2005-01-24 2018-10-11 Merck Sharp & Dohme B.V. Applicator to insert an implant
US7947076B2 (en) * 2005-06-03 2011-05-24 Medtronic Xomed, Inc. Nasal valve treatment method and apparatus
ES2653845T3 (en) 2006-01-17 2018-02-09 Novartis Ag Drug administration treatment device
ES2551782T3 (en) 2006-01-17 2015-11-23 Transcend Medical, Inc. Device for the treatment of glaucoma
BRPI0706472B1 (en) * 2006-01-19 2023-05-16 Merck Sharp & Dohme B.V. KIT AND METHOD FOR ASSEMBLING A DISPOSABLE APPLICATOR AND, DISPOSABLE APPLICATOR
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8668676B2 (en) * 2006-06-19 2014-03-11 Allergan, Inc. Apparatus and methods for implanting particulate ocular implants
US7909789B2 (en) 2006-06-26 2011-03-22 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US8663303B2 (en) 2010-11-15 2014-03-04 Aquesys, Inc. Methods for deploying an intraocular shunt from a deployment device and into an eye
US10085884B2 (en) 2006-06-30 2018-10-02 Aquesys, Inc. Intraocular devices
US8721702B2 (en) 2010-11-15 2014-05-13 Aquesys, Inc. Intraocular shunt deployment devices
US20120123316A1 (en) 2010-11-15 2012-05-17 Aquesys, Inc. Intraocular shunts for placement in the intra-tenon's space
US8308701B2 (en) 2010-11-15 2012-11-13 Aquesys, Inc. Methods for deploying intraocular shunts
US8852256B2 (en) 2010-11-15 2014-10-07 Aquesys, Inc. Methods for intraocular shunt placement
WO2008005873A2 (en) * 2006-06-30 2008-01-10 Aquesys Inc. Methods, systems and apparatus for relieving pressure in an organ
US8911496B2 (en) 2006-07-11 2014-12-16 Refocus Group, Inc. Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods
AU2007272963B2 (en) 2006-07-11 2013-05-23 Refocus Group, Inc. Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods
US20080097335A1 (en) 2006-08-04 2008-04-24 Allergan, Inc. Ocular implant delivery assemblies
US7998108B2 (en) 2006-09-12 2011-08-16 Psivida Us, Inc. Injector apparatus and method of use
US7780730B2 (en) 2006-09-25 2010-08-24 Iyad Saidi Nasal implant introduced through a non-surgical injection technique
US9072514B2 (en) * 2006-10-05 2015-07-07 Thomas P. Knapp Shape memory filament for suture management
US20080086147A1 (en) * 2006-10-05 2008-04-10 Knapp Thomas P Shape memory filament for suture management
US20080097596A1 (en) * 2006-10-18 2008-04-24 Christ F Richard Injection of anti-presbyopia corrective element precursor
US8039010B2 (en) 2006-11-03 2011-10-18 Allergan, Inc. Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier
US8586556B2 (en) * 2006-11-03 2013-11-19 Allergan, Inc. Methods, compositions and drug delivery systems for intraocular delivery of siRNA molecules
EP2088976B1 (en) 2006-11-10 2019-07-03 Glaukos Corporation Uveoscleral shunt
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
CA2670990A1 (en) 2006-12-01 2008-06-12 Allergan, Inc. Method for determining optimum intraocular locations for drug delivery systems
GB0713463D0 (en) 2007-07-11 2007-08-22 Btg Int Ltd Modulators of hypoxia inducible factor-1 and related uses
US20080294149A1 (en) * 2007-05-25 2008-11-27 Arthur Krolman Corneal Viewing Chamber
EP2173289A4 (en) 2007-07-17 2010-11-24 Transcend Medical Inc Ocular implant with hydrogel expansion capabilities
US20090082862A1 (en) 2007-09-24 2009-03-26 Schieber Andrew T Ocular Implant Architectures
US20170360609A9 (en) 2007-09-24 2017-12-21 Ivantis, Inc. Methods and devices for increasing aqueous humor outflow
US8734377B2 (en) 2007-09-24 2014-05-27 Ivantis, Inc. Ocular implants with asymmetric flexibility
US7740604B2 (en) 2007-09-24 2010-06-22 Ivantis, Inc. Ocular implants for placement in schlemm's canal
US8353862B2 (en) * 2007-11-02 2013-01-15 Allergan, Inc. Drug delivery systems and methods
WO2009061988A1 (en) * 2007-11-08 2009-05-14 Alimera Sciences, Inc. Ocular implantation device
US8512404B2 (en) * 2007-11-20 2013-08-20 Ivantis, Inc. Ocular implant delivery system and method
US8808222B2 (en) 2007-11-20 2014-08-19 Ivantis, Inc. Methods and apparatus for delivering ocular implants into the eye
US8337509B2 (en) 2007-11-20 2012-12-25 Ivantis, Inc. Methods and apparatus for delivering ocular implants into the eye
US8652166B2 (en) * 2007-11-30 2014-02-18 Radi Medical Systems Ab Insertion tool for a medical closure device
US20100152646A1 (en) * 2008-02-29 2010-06-17 Reshma Girijavallabhan Intravitreal injection device and method
US8267882B2 (en) 2008-03-05 2012-09-18 Ivantis, Inc. Methods and apparatus for treating glaucoma
WO2009149175A1 (en) 2008-06-04 2009-12-10 Neovista, Inc. Handheld radiation delivery system for advancing a radiation source wire
ES2640867T3 (en) 2008-06-25 2017-11-07 Novartis Ag Eye implant with ability to change shape
US8821870B2 (en) 2008-07-18 2014-09-02 Allergan, Inc. Method for treating atrophic age related macular degeneration
US20100049085A1 (en) * 2008-08-22 2010-02-25 Nock Andrew P Method of making a biopsy marker delivery device
US8532747B2 (en) * 2008-08-22 2013-09-10 Devicor Medical Products, Inc. Biopsy marker delivery device
US9597220B2 (en) 2008-11-19 2017-03-21 Spirox, Inc. Apparatus and methods for correcting nasal valve collapse
ES2786101T3 (en) 2009-01-28 2020-10-08 Alcon Inc Ocular implant with qualities of rigidity, methods and implantation system
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
WO2010088548A1 (en) 2009-01-29 2010-08-05 Forsight Labs, Llc Posterior segment drug delivery
AU2010213840B2 (en) * 2009-02-10 2014-03-20 Eyepoint Pharmaceuticals Us, Inc. Ocular trocar assembly
US9023896B2 (en) * 2009-05-04 2015-05-05 Psivida Us, Inc. Porous silicon drug-eluting particles
US9693899B2 (en) * 2009-07-09 2017-07-04 Ivantis, Inc. Single operator device for delivering an ocular implant
CA2766192C (en) 2009-07-09 2017-10-24 Ivantis, Inc. Ocular implants for residing partially in schlemm's canal
CN102647960A (en) 2009-10-23 2012-08-22 伊万提斯公司 Ocular implant system and method
EP2332494A1 (en) * 2009-12-09 2011-06-15 Neoptics AG Applicator for inserting lenses
WO2011084550A2 (en) * 2009-12-16 2011-07-14 Eyevation, Llc Delivery and extraction devices
US8277418B2 (en) 2009-12-23 2012-10-02 Alcon Research, Ltd. Ophthalmic valved trocar cannula
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US8343106B2 (en) 2009-12-23 2013-01-01 Alcon Research, Ltd. Ophthalmic valved trocar vent
WO2013022801A1 (en) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
JP5856569B2 (en) 2010-02-05 2016-02-10 サイト サイエンシーズ， インコーポレイテッド Device for reducing intraocular pressure and kit including the same
AU2011217785B2 (en) 2010-02-19 2015-06-18 The Regents Of The University Of California Epithelial membrane protein 2 (EMP2) binding reagents and their therapeutic uses in ocular diseases
US9510973B2 (en) 2010-06-23 2016-12-06 Ivantis, Inc. Ocular implants deployed in schlemm's canal of the eye
CN105435338B (en) 2010-08-05 2019-03-26 弗赛特影像4股份有限公司 Injector apparatus and method for drug conveying
WO2012019139A1 (en) 2010-08-05 2012-02-09 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
PL2600812T3 (en) 2010-08-05 2022-01-24 Forsight Vision4, Inc. Apparatus to treat an eye
EP2608740B1 (en) 2010-08-24 2018-06-13 Abbott Medical Optics Inc. Inserter cap and related features
EP3520749A1 (en) 2010-10-15 2019-08-07 Clearside Biomedical, Inc. Device for ocular access
TWI615150B (en) 2010-11-01 2018-02-21 匹史維迪亞美利堅公司 Bioerodible silicon-based devices for delivery of therapeutic agents
US20160256317A1 (en) 2010-11-15 2016-09-08 Aquesys, Inc. Methods for implanting intraocular shunts
RU2013127313A (en) 2010-11-16 2014-12-27 Те Борд Оф Трастиз Оф Те Лилэнд Стэнфорд Джуниор Юниверсити SYSTEMS AND METHODS FOR TREATING A DRY EYE
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
US20140031769A1 (en) 2010-11-19 2014-01-30 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US8657776B2 (en) 2011-06-14 2014-02-25 Ivantis, Inc. Ocular implants for delivery into the eye
EP4249059A3 (en) 2011-06-28 2023-11-29 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
SI2755600T1 (en) 2011-09-16 2021-08-31 Forsight Vision4, Inc. Fluid exchange apparatus
US8852136B2 (en) 2011-12-08 2014-10-07 Aquesys, Inc. Methods for placing a shunt into the intra-scleral space
US8765210B2 (en) 2011-12-08 2014-07-01 Aquesys, Inc. Systems and methods for making gelatin shunts
US9808373B2 (en) 2013-06-28 2017-11-07 Aquesys, Inc. Intraocular shunt implantation
US9610195B2 (en) 2013-02-27 2017-04-04 Aquesys, Inc. Intraocular shunt implantation methods and devices
US10080682B2 (en) 2011-12-08 2018-09-25 Aquesys, Inc. Intrascleral shunt placement
US8945214B2 (en) 2011-12-19 2015-02-03 Allergan, Inc. Intravitreal applicator
US8663150B2 (en) 2011-12-19 2014-03-04 Ivantis, Inc. Delivering ocular implants into the eye
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
US10272234B2 (en) 2012-02-23 2019-04-30 Unl Holdings Llc Devices for targeted delivery of therapeutic implants
CN104582767B (en) 2012-02-23 2018-11-06 尤尼特拉克特注射器控股有限公司 Bounce back needle safety syringe
WO2013126853A2 (en) 2012-02-23 2013-08-29 Unitract Syringe Pty Ltd Devices for targeted delivery of therapeutic implants
JP6208737B2 (en) * 2012-03-19 2017-10-04 クック・メディカル・テクノロジーズ・リミテッド・ライアビリティ・カンパニーＣｏｏｋ Ｍｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ Medical device, method, and kit for delivering a drug into a body passage
US9855167B2 (en) 2012-03-20 2018-01-02 Sight Sciences, Inc. Ocular delivery systems and methods
WO2013148275A2 (en) 2012-03-26 2013-10-03 Glaukos Corporation System and method for delivering multiple ocular implants
US9358156B2 (en) 2012-04-18 2016-06-07 Invantis, Inc. Ocular implants for delivery into an anterior chamber of the eye
EP3730103A1 (en) * 2012-04-19 2020-10-28 Alcon Inc. Delivery system for ocular implant
US10085633B2 (en) * 2012-04-19 2018-10-02 Novartis Ag Direct visualization system for glaucoma treatment
AU2013204739B2 (en) * 2012-04-21 2016-10-20 Paul Jason Barrot Apparatus for plugging holes
US9241832B2 (en) 2012-04-24 2016-01-26 Transcend Medical, Inc. Delivery system for ocular implant
US9724191B2 (en) 2012-06-04 2017-08-08 Alcon Pharmaceuticals, Ltd. Intraocular lens inserter
EP3228286A1 (en) 2012-09-17 2017-10-11 Novartis AG Expanding ocular impant devices
US20150290170A1 (en) 2012-10-26 2015-10-15 Allergan, Inc. Ketorolac-containing sustained release drug delivery systems
CA2890471C (en) 2012-11-08 2021-07-27 Clearside Biomedical, Inc. Methods and devices for the treatment of ocular diseases in human subjects
WO2014078288A1 (en) 2012-11-14 2014-05-22 Transcend Medical, Inc. Flow promoting ocular implant
WO2014085450A1 (en) 2012-11-28 2014-06-05 Ivantis, Inc. Apparatus for delivering ocular implants into an anterior chamber of the eye
US10159600B2 (en) 2013-02-19 2018-12-25 Aquesys, Inc. Adjustable intraocular flow regulation
EP3400906A1 (en) 2013-02-27 2018-11-14 Spirox, Inc. Nasal implants
US9717627B2 (en) 2013-03-12 2017-08-01 Oculeve, Inc. Implant delivery devices, systems, and methods
EP2968113B8 (en) 2013-03-14 2020-10-28 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
WO2014160278A1 (en) 2013-03-14 2014-10-02 Allergan, Inc. Polymer system for securing implants in syringe needles
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
RU2705986C2 (en) 2013-03-15 2019-11-13 Айпоинт Фармасьютикалз Юэс, Инк. Biodegradable silicone-based compositions for delivering therapeutic agents
CN105246438B (en) 2013-03-28 2018-01-26 弗赛特影像4股份有限公司 For conveying the ophthalmic implant of therapeutic substance
US9987163B2 (en) 2013-04-16 2018-06-05 Novartis Ag Device for dispensing intraocular substances
NZ704579A (en) 2013-04-19 2018-10-26 Oculeve Inc Nasal stimulation devices and methods
SG10201702674PA (en) 2013-05-03 2017-06-29 Clearside Biomedical Inc Apparatus and methods for ocular injection
EP3003454B1 (en) 2013-06-03 2020-01-08 Clearside Biomedical, Inc. Apparatus for drug delivery using multiple reservoirs
US9649223B2 (en) * 2013-06-13 2017-05-16 Innfocus, Inc. Inserter for tubular medical implant devices
WO2015032740A1 (en) * 2013-09-05 2015-03-12 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a needle insertion arrangement
DE102013015845A1 (en) * 2013-09-24 2015-03-26 Urotech Gmbh Placement device for a medical catheter
EP3068354B1 (en) 2013-11-14 2023-06-28 Aquesys, Inc. Intraocular shunt inserter
US9770583B2 (en) 2014-02-25 2017-09-26 Oculeve, Inc. Polymer formulations for nasolacrimal stimulation
US10780218B2 (en) * 2014-02-26 2020-09-22 Allergan, Inc. Intraocular implant delivery apparatus and methods of use thereof
WO2015154049A1 (en) 2014-04-04 2015-10-08 Altaviz, Llc Intraocular lens inserter
CA2952958A1 (en) 2014-06-20 2015-12-23 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
WO2016011056A1 (en) 2014-07-14 2016-01-21 Ivantis, Inc. Ocular implant delivery system and method
RU2695562C2 (en) 2014-07-15 2019-07-24 Алькон Фармасьютикалз, Лтд. Device for insertion of intraocular lens with temperature compensation
MY182497A (en) 2014-07-15 2021-01-25 Forsight Vision4 Inc Ocular implant delivery device and method
EP3673952A1 (en) 2014-07-25 2020-07-01 Oculeve, Inc. Stimulation patterns for treating dry eye
BR112017002466A2 (en) 2014-08-08 2017-12-05 Forsight Vision4 Inc stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods for their preparation
WO2016033196A1 (en) 2014-08-26 2016-03-03 Spirox, Inc. Nasal implants and systems and method of use
US10363163B2 (en) 2014-09-11 2019-07-30 EyePoint Pharmaceuticals, Inc. Injector apparatus
US10207108B2 (en) 2014-10-22 2019-02-19 Oculeve, Inc. Implantable nasal stimulator systems and methods
CA2965514A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Contact lens for increasing tear production
CN107106843A (en) 2014-10-22 2017-08-29 奥库利维公司 Stimulating apparatus and method for treating xerophthalmia
SG11201703726XA (en) 2014-11-10 2017-06-29 Forsight Vision4 Inc Expandable drug delivery devices and method of use
FR3028410A1 (en) 2014-11-18 2016-05-20 Pierre Coulon MULTIFUNCTIONAL CAPSULAR IMPLANT
WO2016123027A1 (en) * 2015-01-26 2016-08-04 Nano Precision Medical, Inc. Apparatus and method for promoting fluid uptake into an implant
US10588780B2 (en) 2015-03-04 2020-03-17 Alcon Inc. Intraocular lens injector
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
UA122570C2 (en) 2015-06-03 2020-12-10 Аквісіс, Інк. Ab externo intraocular shunt placement
KR102650751B1 (en) * 2015-06-03 2024-03-22 인타르시아 세라퓨틱스 인코포레이티드 Implant placement and removal systems
US11730890B1 (en) * 2020-01-07 2023-08-22 Gholam A. Peyman Plungerless aspiration and/or injection device and method using the same
WO2017020001A2 (en) 2015-07-29 2017-02-02 Allergan, Inc. Heavy chain only antibodies to ang-2
CA2992788A1 (en) 2015-08-14 2017-02-23 Allergan, Inc. Heavy chain only antibodies to pdgf
US11197779B2 (en) 2015-08-14 2021-12-14 Ivantis, Inc. Ocular implant with pressure sensor and delivery system
WO2017053824A1 (en) 2015-09-25 2017-03-30 Spirox, Inc. Nasal implants and systems and method of use
USD851755S1 (en) 2015-10-22 2019-06-18 Eyepoint Pharmaceuticals Us, Inc. Ocular inserter
US10172706B2 (en) 2015-10-31 2019-01-08 Novartis Ag Intraocular lens inserter
RU2734958C2 (en) 2015-11-18 2020-10-26 Формикон Аг Pre-filled pharmaceutical package containing a liquid formulation based on a vegf antagonist
CA3005132A1 (en) * 2015-11-18 2017-05-26 Sio2 Medical Products, Inc. Pharmaceutical package for ophthalmic formulations
KR20180084104A (en) 2015-11-20 2018-07-24 포사이트 비젼4, 인크. Porous structures for extended release drug delivery devices
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
WO2017106517A1 (en) 2015-12-15 2017-06-22 Ivantis, Inc. Ocular implant and delivery system
CN105411742A (en) * 2015-12-24 2016-03-23 陈园园 Forceps for ophthalmologic operation
US20190038463A1 (en) * 2016-01-28 2019-02-07 Aq Biomed, Llc Ophthalamic implant for reduction of intraocular pressure in glaucomatous eyes and method of use
WO2017139375A1 (en) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
JP7009384B2 (en) 2016-04-05 2022-01-25 フォーサイト・ビジョン フォー・インコーポレーテッド Implantable eye drug delivery device
EP3451894B1 (en) 2016-05-02 2023-11-15 Entellus Medical, Inc. Nasal valve implants
JP2019514581A (en) 2016-05-02 2019-06-06 クリアサイド バイオメディカル，インコーポレイテッド Systems and methods for ocular drug delivery
AU2017260237A1 (en) 2016-05-02 2018-11-22 Oculeve, Inc. Intranasal stimulation for treatment of meibomian gland disease and blepharitis
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CA3025526A1 (en) 2016-06-02 2017-12-07 Aquesys, Inc. Intraocular drug delivery
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
CN106038053B (en) * 2016-07-05 2018-11-20 颜繁诚 Medicine-filling device after eyeball
CN110177527B (en) 2016-08-12 2022-02-01 科尼尔赛德生物医学公司 Device and method for adjusting insertion depth of needle for medicament delivery
US20190374380A1 (en) * 2016-09-02 2019-12-12 Envisia Therapeutics, Inc. Implant applicators
CN110022755A (en) 2016-12-02 2019-07-16 奥库利维公司 Device and method for xerophthalmia prediction and treatment recommendations
US11000367B2 (en) 2017-01-13 2021-05-11 Alcon Inc. Intraocular lens injector
US10568735B2 (en) 2017-01-13 2020-02-25 Alcon Inc. Intraocular lens injector
WO2018183561A1 (en) 2017-03-28 2018-10-04 Spirox, Inc. Nasal delivery tools, systems, and methods of use
US11116625B2 (en) 2017-09-28 2021-09-14 Glaukos Corporation Apparatus and method for controlling placement of intraocular implants
EP3691586A2 (en) 2017-10-06 2020-08-12 Glaukos Corporation Systems and methods for delivering multiple ocular implants
USD846738S1 (en) 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus
US11246753B2 (en) 2017-11-08 2022-02-15 Aquesys, Inc. Manually adjustable intraocular flow regulation
WO2019103906A1 (en) 2017-11-21 2019-05-31 Forsight Vision4, Inc. Fluid exchange apparatus for expandable port delivery system and methods of use
US11135089B2 (en) 2018-03-09 2021-10-05 Aquesys, Inc. Intraocular shunt inserter
US10952898B2 (en) 2018-03-09 2021-03-23 Aquesys, Inc. Intraocular shunt inserter
CN108524095A (en) * 2018-04-16 2018-09-14 温州医科大学 A kind of ocular implantation material injection device
FR3080290B1 (en) 2018-04-18 2021-10-29 Nemera La Verpilliere IMPLANT INJECTION DEVICE WITH SEQUENTIAL RELEASE PUSHING MEANS
FR3080289B1 (en) 2018-04-18 2021-10-29 Nemera La Verpilliere IMPLANT INJECTION DEVICE WITH FRICTION RETAINING MEANS
FR3080291B1 (en) 2018-04-18 2023-06-16 Nemera La Verpilliere IMPLANT INJECTION DEVICE HAVING A RACK AND PINION TYPE TRANSMISSION
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
US10849739B2 (en) * 2018-08-02 2020-12-01 Carl Zeiss Meditec Ag Ophthalmosurgical injector system
US11116626B2 (en) * 2018-12-19 2021-09-14 Alcon Inc. IOL injector having a lever-driven plunger mechanism
CA3139090A1 (en) 2019-06-27 2020-12-30 Alcon Inc. Iol base compression device having an iol towing mechanism
JP7328047B2 (en) * 2019-07-25 2023-08-16 朝日インテック株式会社 chemical injector
US11357621B2 (en) * 2019-08-06 2022-06-14 Alcon Inc. Lever-actuated drive
CN110584874B (en) * 2019-08-26 2022-05-06 江苏百视通医疗器械有限公司 Implant conveying device
US11504270B1 (en) 2019-09-27 2022-11-22 Sight Sciences, Inc. Ocular delivery systems and methods
US11464914B2 (en) * 2019-10-21 2022-10-11 Ripple Therapeutics Corporation Intravitreal injector
FI3884929T3 (en) 2020-03-25 2023-08-07 Ocular Therapeutix Inc Ocular implant containing a tyrosine kinase inhibitor
KR102380848B1 (en) * 2020-04-25 2022-03-31 주식회사 오엘테크 Method of Manufacturing Implant Cartridge for Treating Macular Degeneration
EP4274529A1 (en) 2021-01-11 2023-11-15 Alcon Inc. Systems and methods for viscoelastic delivery
CN114983670A (en) * 2022-05-30 2022-09-02 海思盖德(苏州)生物医学科技有限公司 Intraocular implant conveyer
CN115645145B (en) * 2022-11-14 2023-02-28 海思盖德(苏州)生物医学科技有限公司 Intraocular implant transporter and delivery system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284479A (en) * 1989-08-30 1994-02-08 N.V. Nederlandsche Apparatenfabriek Nedap Implanter

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3220413A (en) * 1961-04-03 1965-11-30 Sunnen Joseph Applicator
US3238941A (en) * 1963-06-19 1966-03-08 Frost Eng Dev Balling gun
US3698390A (en) * 1969-10-27 1972-10-17 Frank Donald Ferris Dispensing for medicaments
US3937370A (en) * 1974-08-14 1976-02-10 Baxter Laboratories, Inc. Controlled depth aspiration cannula
US4144317A (en) 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
GB2138298B (en) * 1983-04-21 1986-11-05 Hundon Forge Ltd Pellet implanter
US4659326A (en) * 1984-08-20 1987-04-21 Johnson Ronald F Apparatus for implanting implants in cattle
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
SU1419676A1 (en) * 1985-12-16 1988-08-30 Московский научно-исследовательский институт микрохирургии глаза Apparatus for coagulation of biological tissues
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
EP0255123A3 (en) * 1986-07-30 1988-04-20 Sumitomo Pharmaceuticals Company, Limited Solid preparation administering instrument
US4919130A (en) * 1986-11-07 1990-04-24 Nestle S.A. Tool for inserting compressible intraocular lenses into the eye and method
US4850970A (en) * 1987-03-26 1989-07-25 American Home Products, Corp. Two part mastitis cannula cap
ATE71543T1 (en) * 1987-08-18 1992-02-15 Akzo Nv INJECTION DEVICE FOR AN IMPLANT.
US4997652A (en) * 1987-12-22 1991-03-05 Visionex Biodegradable ocular implants
US4853224A (en) * 1987-12-22 1989-08-01 Visionex Biodegradable ocular implants
US4907587A (en) * 1988-10-12 1990-03-13 Fedorov Svjatoslav N Method for surgical correction of mixed and hypermetropic astigmatism and a device for carrying same into effect
DE3903956A1 (en) * 1989-02-10 1990-08-16 Guenter Dr Lohrmann GUIDE DEVICE FOR A PUNCHING BIOPSIA NEEDLE CONNECTED TO A BIOPSI PUNCHING DEVICE
US5098443A (en) 1989-03-23 1992-03-24 University Of Miami Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents
US5336206A (en) * 1989-08-15 1994-08-09 United States Surgical Corporation Trocar penetration depth indicator and guide tube positioning device
NL8902186A (en) 1989-08-30 1991-03-18 Nedap Nv RECHARGEABLE IMPLANT TOOL WITH AUTOMATIC RELEASE.
US5164188A (en) * 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
GB2240718A (en) * 1990-02-09 1991-08-14 Hundon Forge Ltd Implanting device with needle cover
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5278554A (en) * 1991-04-05 1994-01-11 Marton Louis L Road traffic control system with alternating nonstop traffic flow
US5178635A (en) 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US5250026A (en) * 1992-05-27 1993-10-05 Destron/Idi, Inc. Adjustable precision transponder injector
US5807400A (en) * 1992-09-30 1998-09-15 Staar Surgical Company, Inc. Deformable intraocular lens insertion system
US5860984A (en) * 1992-09-30 1999-01-19 Staar Surgical Company, Inc. Spring biased deformable intraocular injecting apparatus
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5439473A (en) * 1993-12-13 1995-08-08 Modulohm A/S Safety lancet
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5451213A (en) * 1994-05-31 1995-09-19 Log Plastic Products Protective device for syringe needles
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5542920A (en) * 1994-09-12 1996-08-06 Delab Needle-less parenteral introduction device
US5725521A (en) * 1996-03-29 1998-03-10 Eclipse Surgical Technologies, Inc. Depth stop apparatus and method for laser-assisted transmyocardial revascularization and other surgical applications
US5824001A (en) * 1996-06-10 1998-10-20 Becton Dickinson And Company Radially vented flashback chamber and plug assembly
US5941250A (en) * 1996-11-21 1999-08-24 University Of Louisville Research Foundation Inc. Retinal tissue implantation method
US5876373A (en) * 1997-04-04 1999-03-02 Eclipse Surgical Technologies, Inc. Steerable catheter
CN2291910Y (en) * 1997-04-18 1998-09-23 李钟实 Coaxial perfusion type artificial crystal embedding apparatus
US6203513B1 (en) * 1997-11-20 2001-03-20 Optonol Ltd. Flow regulating implant, method of manufacture, and delivery device
IL137095A0 (en) * 1997-12-29 2001-06-14 Alza Corp Implanter device for subcutaneous implants
US5957892A (en) * 1998-03-12 1999-09-28 Specialized Health Products, Inc. Safety catheter insertion apparatus and methods
MY128127A (en) 1998-04-23 2007-01-31 Alza Corp Trocar for inserting implants
US6224565B1 (en) * 1998-11-13 2001-05-01 Sound Surgical Technologies, Llc Protective sheath and method for ultrasonic probes
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6159218A (en) * 1999-05-19 2000-12-12 Aramant; Robert B. Retinal tissue implantation tool
US6558342B1 (en) * 1999-06-02 2003-05-06 Optonol Ltd. Flow control device, introducer and method of implanting
US6383191B1 (en) * 2000-03-15 2002-05-07 Sdgi Holdings, Inc. Laparoscopic instrument sleeve
US6514270B1 (en) * 2000-11-10 2003-02-04 Steven Schraga Single use lancet device

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284479A (en) * 1989-08-30 1994-02-08 N.V. Nederlandsche Apparatenfabriek Nedap Implanter

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9012437B2 (en) 2000-07-05 2015-04-21 Allergan, Inc. Implants and methods for treating inflammation-mediated conditions of the eye
US9283178B2 (en) 2000-11-29 2016-03-15 Allergan, Inc. Methods for treating edema in the eye and intraocular implants for use therefor
US9592242B2 (en) 2000-11-29 2017-03-14 Allergan, Inc. Methods for treating edema in the eye and intraocular implants for use therefor
US9192511B2 (en) 2003-01-09 2015-11-24 Allergan, Inc. Ocular implant made by a double extrusion process
US8911768B2 (en) 2004-04-30 2014-12-16 Allergan, Inc. Methods for treating retinopathy with extended therapeutic effect
US9233071B2 (en) 2004-04-30 2016-01-12 Allergan, Inc. Methods for treating retinopathy with extended therapeutic effect

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