WO2003043569A3 - Trans-10, cis-12 conjugated linoleic acid isomer for the treatment of diseases - Google Patents

Trans-10, cis-12 conjugated linoleic acid isomer for the treatment of diseases Download PDF

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Publication number
WO2003043569A3
WO2003043569A3 PCT/US2002/036684 US0236684W WO03043569A3 WO 2003043569 A3 WO2003043569 A3 WO 2003043569A3 US 0236684 W US0236684 W US 0236684W WO 03043569 A3 WO03043569 A3 WO 03043569A3
Authority
WO
WIPO (PCT)
Prior art keywords
cis
linoleic acid
conjugated linoleic
acid isomer
trans
Prior art date
Application number
PCT/US2002/036684
Other languages
French (fr)
Other versions
WO2003043569A2 (en
Inventor
James R Komorowski
Vijaya Juturu
Danielle Greenberg
Original Assignee
Nutrition 21 Inc
James R Komorowski
Vijaya Juturu
Danielle Greenberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrition 21 Inc, James R Komorowski, Vijaya Juturu, Danielle Greenberg filed Critical Nutrition 21 Inc
Priority to AU2002357729A priority Critical patent/AU2002357729A1/en
Publication of WO2003043569A2 publication Critical patent/WO2003043569A2/en
Publication of WO2003043569A3 publication Critical patent/WO2003043569A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A composition for treating insulin- or non-insulin-dependent diabetes, reducing body fat, improving insulin sensitivity, reducing hyperglycemia, and reducing hypercholesterolemia with conjugated linoleic acid isomer trans-10, cis-12 alone, or in combination with any form of a trivalent chromium complex is disclosed. A method of treating a subject suffering from insulin-dependent diabetes by administering a composition that includes conjugated linoleic acid isomer trans-10, cis-12 alone, or in combination with any form of a trivalent chromium complex is similarly provided. The administration of a composition containing an effective dose of conjugated linoleic acid isomer trans-10, cis-12 alone, or in combination with any form of a trivalent chromium complex for the treatment of obesity is likewise provided.
PCT/US2002/036684 2001-11-16 2002-11-12 Trans-10, cis-12 conjugated linoleic acid isomer for the treatment of diseases WO2003043569A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002357729A AU2002357729A1 (en) 2001-11-16 2002-11-12 Trans-10, cis-12 conjugated linoleic acid isomer for the treatment of diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33249601P 2001-11-16 2001-11-16
US60/332,496 2001-11-16

Publications (2)

Publication Number Publication Date
WO2003043569A2 WO2003043569A2 (en) 2003-05-30
WO2003043569A3 true WO2003043569A3 (en) 2003-10-30

Family

ID=23298480

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/036684 WO2003043569A2 (en) 2001-11-16 2002-11-12 Trans-10, cis-12 conjugated linoleic acid isomer for the treatment of diseases

Country Status (2)

Country Link
AU (1) AU2002357729A1 (en)
WO (1) WO2003043569A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8933022B2 (en) 2011-03-01 2015-01-13 Jds Therapeutics, Llc Methods and compositions for the treatment and prevention Hypoglycemia and related disorders
US9005637B2 (en) 2007-06-26 2015-04-14 Jds Therapeutics, Llc Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement
US9119835B2 (en) 2007-03-13 2015-09-01 JDS Therapeautics, LLC Methods and compositions for the sustained release of chromium

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2396081T1 (en) 2009-02-16 2017-09-29 Nogra Pharma Limited Alkylamido compounds and uses thereof
JP6301844B2 (en) 2012-02-09 2018-03-28 ノグラ ファーマ リミテッド How to treat fibrosis
MX2018009748A (en) 2016-02-11 2019-02-07 Nutrition 21 Llc Chromium containing compositions for improving health and fitness.
MA43682A (en) * 2016-02-26 2018-11-28 Nogra Pharma Ltd LACTOSE INTOLERANCE TREATMENT METHODS
MX2021009498A (en) 2019-02-08 2021-09-08 Nogra Pharma Ltd Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof.
CN115245510A (en) * 2021-04-28 2022-10-28 扬州大学 Application of trans-10, cis-12 conjugated linoleic acid

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948772A (en) * 1998-08-28 1999-09-07 Ambi Inc. Chromium picolinate compositions and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948772A (en) * 1998-08-28 1999-09-07 Ambi Inc. Chromium picolinate compositions and uses thereof
US6093711A (en) * 1998-08-28 2000-07-25 Ambi Inc. Enteric-coated chromium picolinate compositions and uses thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9119835B2 (en) 2007-03-13 2015-09-01 JDS Therapeautics, LLC Methods and compositions for the sustained release of chromium
US9597404B2 (en) 2007-03-13 2017-03-21 Jds Therapeutics, Llc Methods and compositions for sustained release of chromium
US9005637B2 (en) 2007-06-26 2015-04-14 Jds Therapeutics, Llc Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement
US9421170B2 (en) 2007-06-26 2016-08-23 Jds Therapeutics, Llc Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement
US11850308B2 (en) 2007-06-26 2023-12-26 Bonafide Health, Llc Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement
US8933022B2 (en) 2011-03-01 2015-01-13 Jds Therapeutics, Llc Methods and compositions for the treatment and prevention Hypoglycemia and related disorders

Also Published As

Publication number Publication date
AU2002357729A8 (en) 2003-06-10
WO2003043569A2 (en) 2003-05-30
AU2002357729A1 (en) 2003-06-10

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