WO2003042661A2 - Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer - Google Patents

Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer Download PDF

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Publication number
WO2003042661A2
WO2003042661A2 PCT/US2002/036810 US0236810W WO03042661A2 WO 2003042661 A2 WO2003042661 A2 WO 2003042661A2 US 0236810 W US0236810 W US 0236810W WO 03042661 A2 WO03042661 A2 WO 03042661A2
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Prior art keywords
cancer
protein
sequence
nucleic acid
cell
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PCT/US2002/036810
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French (fr)
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WO2003042661A8 (en
WO2003042661A3 (en
Inventor
Daniel Afar
Natasha Aziz
Wendy M. Ginsburg
Kurt C. Gish
Richard Glynne
Peter A. Hevezi
David H. Mack
Richard Murray
Susan R. Watson
Keith E. Wilson
Albert Zlotnik
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Protein Design Labs, Inc.
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Priority to CA002467433A priority Critical patent/CA2467433A1/en
Priority to EP02792272A priority patent/EP1497454A2/en
Priority to JP2003544445A priority patent/JP2005525789A/en
Priority to AU2002357734A priority patent/AU2002357734A1/en
Publication of WO2003042661A2 publication Critical patent/WO2003042661A2/en
Publication of WO2003042661A8 publication Critical patent/WO2003042661A8/en
Publication of WO2003042661A3 publication Critical patent/WO2003042661A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Definitions

  • the invention relates to the identification of nucleic acid and protein expression profiles and nucleic acids, products, and antibodies thereto that are involved in cancer and other diseases; and to the use of such expression profiles and compositions in the diagnosis, prognosis, and therapy of these conditions.
  • the invention further relates to methods for identifying and using agents and/or targets that modulate these conditions.
  • Cancers share the charactaristic of disordered control over normal cell division, growth, and differentiation. Their initial clinical manifestations are extremely heterogeneous, with over 70 types of cancer arising in virtually every organ and tissue of the body. Moreover, some of those similarly classified cancer types may represent multiple different molecular diseases. Unfortunately, some cancers may be virtually asymptomatic until late in the disease course, when treatment is more difficult, and prognosis grim. Treatment for cancer typically includes surgery, chemotherapy, and/or radiation therapy.
  • antigens examples include Her2/neu and the B-cell antigen CD20.
  • Humanized monclonal antibodies directed to Her2/neu are currently in use for the treatment of metastatic breast cancer. See Ross and Fletcher (1998) Stem Cells 16:413-428.
  • anti-CD20 monoclonal antibodies are used to effectively treat non-Hodgkin's lymphoma. See Maloney, et al. (1997) Blood 90:2188-2195; Leget and Czuczman (1998) Curr. Opin. Oncol. 10:548-551.
  • provided herein are molecular targets for therapeutic intervention in various defined cancers. Additionally, provided herein are methods that can be used in diagnosis and prognosis of cancer. Further provided are methods that can be used to screen candidate bioactive agents for the ability to modulate cancer.
  • the present invention provides methods for determining the presence or absence of a pathological cell in a patient, the method comprising detecting a nucleic acid comprising a sequence at least 80% identical to a sequence as described in Tables 2A-80 in a biological sample from the patient, thereby determining the presence or absence of the pathological cell.
  • the pathology is described in Table 1, including a cancer;
  • the biological sample comprises isolated nucleic acids;
  • the nucleic acids are mRNA;
  • the biological sample is tissue from an organ which is affected by the pathology of Table 1, including a cancer;
  • a further step is used of amplifying nucleic acids before the step of detecting the nucleic acid;
  • the detecting is of a protein encoded by the nucleic acid;
  • the nucleic acid comprises a sequence as described in Tables 2A-80;
  • the detecting step is carried out by using a labeled nucleic acid probe, utilizing a biochip comprising at sequence at least 80% identical to a sequence as described in Tables 2A-80, or detecting a polypeptide encoded by the nucleic acid; or the patient is undergoing a therapeutic regimen to treat the pathology of Table 1, or is suspected of having the pathology or cancer.
  • compositions are also provided, e.g., an isolated nucleic acid molecule comprising a sequence as described in Tables 2A-80, including, e.g., those which are labeled; an expression vector comprising such nucleic acid; a host cell comprising such expression vector; an isolated polypeptide which is encoded by such a nucleic acid molecule comprising a sequence as described in Tables 2A-80; or an antibody that specifically binds the polypeptide.
  • the antibody is: conjugated to an effector component, is conjugated to a detectable label (including, e.g., a fluorescent label, a radioisotope, or a cytotoxic chemical), an antibody fragment, or is a humanized antibody.
  • Additional methods are provided, including methods for specifically targeting a compound to a pathological cell in a patient, the method comprising administering to the patient an antibody, as described, thereby providing the targetting.
  • Others include, e.g., methods for determining the presence or absence of a pathological cell in a patient, the methods comprising contacting a biological sample with an antibody, as described.
  • the antibody is: conjugated to an effector component, or to a fluorescent label; or the biological sample is a blood, serum, urine, or stool sample.
  • Further methods include those for identifying a compound that modulates a pathology- associated polypeptide, the method comprising steps of: contacting the compound with a pathology-associated polypeptide, the polypeptide encoded by a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as described in Tables 2A-80; and determining the functional effect of the compound upon the polypeptide.
  • Another drug screening assay method comprises steps of: administering a test compound to a mammal having a pathology of Table 1 or a cell isolated therefrom; and comparing the level of gene expression of a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as described in Tables 2A-80 in a treated cell or mammal with the level of gene expression of the polynucleotide in a control cell or mammal, wherein a test compound that modulates the level of expression of the polynucleotide is a candidate for the treatment of the pathology.
  • the present invention provides novel methods for diagnosis and prognosis evaluation for various disorders, e.g., angiogenesis, fibrosis, and various defined forms of cancer, including metastatic cancer, as well as methods for screening for compositions which modulate such conditions. Also provided are methods for treating such disorders or cancers. See, e.g., American Society of Clinical Oncology (ed. 2001) ASCO Curriculum: Symptom Management Kendall/Hunt, ISBN: 0787277851; Bonadonna, et al. (2001) Textbook of Breast Cancer (2d ed.) Dunitz Martin, ISBN: 1853178241; Devita and Hellman (eds.
  • identification of markers selectively expressed on defined cancers allows for use of that expression in diagnostic, prognostic, or therapeutic methods.
  • the invention defines various compositions, e.g., nucleic acids, polypeptides, antibodies, and small molecule agonists/antagonists, which will be useful to selectively identify those markers.
  • therapeutic methods may take the form of protein therapeutics which use the marker expression for selective localization or modulation of function (for those markers which have a causative disease effect), for vaccines, identification of binding partners, or antagonism, e.g., using antisense or RNAi.
  • the markers may be useful for molecular characterization of subsets of the diseases, e.g., as provided in Table 1, which subsets may actually require very different treatments. Moreover, the markers may also be important in related diseases to the specific disorders and cancers, e.g., which affect similar tissues in non-malignant diseases, or have similar mechanisms of induction/maintenance. Metastatic processes or characteristics may also be targeted. Diagnostic and prognostic uses are made available, e.g., to subset related but distinct diseases, or to determine treatment strategy. The detection methods may be based upon nucleic acid, e.g., PCR or hybridization techniques, or protein, e.g., ELISA, imaging, JJHC, etc.
  • Tables 2B-76B provide unigene cluster identification numbers for the nucleotide sequence of genes that exhibit increased or decreased expression in diseased samples (see Tables 1-3), particularly sequences involved in angiogenesis, arthritis, prostate cancer, breast cancer, colorectal cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, ovarian cancer, pancreatic cancer, renal cancer, stomach cancer, skin cancer, testicular cancer, uterine cancer, glioblastoma, Ewing sarcoma, soft tissue sarcoma, and lung fibrosis.
  • Tables 2A-80 also provide an exemplar accession number that provides a nucleotide sequence that is part of the unigene cluster. Definitions
  • cancer protein or “cancer polynucleotide” or “cancer-associated transcript” refers to nucleic acid and polypeptide polymo ⁇ hic variants, alleles, mutants, and interspecies homologues that: (1) have a nucleotide sequence that has greater than about 60% nucleotide sequence identity, 65%, 70%, 75%, 80%, 85%, 90%, preferably about 92%, 94%, 96%, 97%, 98%, or 99% or greater nucleotide sequence identity, preferably over a region of over a region of at least about 25, 50, 100, 200, 500, 1000, or more nucleotides, to a nucleotide sequence of or associated with a gene of Tables 1-80; (2) bind to antibodies, e.g., polyclonal antibodies, raised against an immunogen comprising an amino acid sequence encoded by a nucleotide sequence of or associated with a gene of Tables 1-80, and conservatively modified variants thereof; (3) specifically hybridize
  • a polynucleotide or polypeptide sequence is typically from a mammal including, but not limited to, primate, e.g., human; rodent, e.g., rat, mouse, hamster; cow, pig, horse, sheep, or other mammal.
  • primate e.g., human
  • rodent e.g., rat, mouse, hamster
  • a “cancer polypeptide” and a “cancer polynucleotide,” include both naturally occurring or recombinant forms.
  • a “full length” cancer protein or nucleic acid refers to a cancer polypeptide or polynucleotide sequence, or a variant thereof, that contains elements normally contained in one or more naturally occurring, wild type cancer polynucleotide or polypeptide sequences.
  • the “full length” may be prior to, or after, various stages of post-translational processing or splicing, including alternative splicing.
  • Bio sample as used herein is a sample of biological tissue or fluid that contains nucleic acids or polypeptides, e.g., of a cancer protein, polynucleotide, or transcript.
  • samples include, but are not limited to, tissue isolated from primates, e.g., humans, or rodents, e.g., mice, and rats.
  • Biological samples may also include sections of tissues such as biopsy and autopsy samples, frozen sections taken for histologic pu ⁇ oses, archival samples, blood, plasma, serum, sputum, stool, tears, mucus, hair, skin, etc.
  • Biological samples also include explants and primary and/or transformed cell cultures derived from patient tissues.
  • a biological sample is typically obtained from a eukaryotic organism, most preferably a mammal such as a primate, e.g., chimpanzee or human; cow; dog; cat; a rodent, e.g., guinea pig, rat, mouse; rabbit; or a bird; reptile; or fish. Livestock and domestic animals are of interest.
  • Providing a biological sample means to obtain a biological sample for use in methods described in this invention. Most often, this will be done by removing a sample of cells from an animal, but can also be accomplished by using previously isolated cells (e.g., isolated by another person, at another time, and/or for another pu ⁇ ose), or by performing the methods of the invention in vivo. Archival tissues or materials, having treatment or outcome history, will be particularly useful.
  • nucleic acids or polypeptide sequences refer to two or more sequences or subsequences that are the same or have a specified percentage of amino acid residues or nucleotides that are the same (e.g., about 70% identity, preferably 75%, 80%, 85%, 90%, 91%, 93%, 95%, 97%, 98%, 99%, or higher identity over a specified region, when compared and aligned for maximum correspondence over a comparison window or designated region) as measured using, e.g., a BLAST or BLAST 2.0 sequence comparison algorithms with default parameters described below, or by manual alignment and visual inspection (see, e.g., NCBI web site http://www.ncbi.nlm.nih.gov/BLAST/ or the like).
  • sequences are then said to be “substantially identical.”
  • This definition also refers to, or may be applied to, the complement of a test sequence.
  • the definition also includes sequences that have deletions and/or insertions, substitutions, and naturally occurring, e.g., polymo ⁇ hic or allelic variants, and man-made variants.
  • the preferred algorithms can account for gaps and the like.
  • identity exists over a region that is at least about 25 amino acids or nucleotides in length, or more preferably over a region that is about 50-100 amino acids or nucleotides in length.
  • For sequence comparison typically one sequence acts as a reference sequence, to which test sequences are compared.
  • test and reference sequences are entered into a computer, subsequence coordinates are designated, if necessary, and sequence algorithm program parameters are designated. Preferably, default program parameters can be used, or alternative parameters can be designated.
  • the sequence comparison algorithm then calculates the percent sequence identities for the test sequences relative to the reference sequence, based on the program parameters.
  • a "comparison window" includes reference to a segment of contiguous positions selected from the group consisting typically of from about 20 to 600, usually about 50 to 200, more usually about 100 to 150, in which a sequence may be compared to a reference sequence of the same number of contiguous positions after the two sequences are optimally aligned. Methods of alignment of sequences for comparison are well-known.
  • Optimal alignment of sequences for comparison can be conducted, e.g., by the local homology algorithm of Smith and Waterman (1981) Adv. Appl. Math. 2:482-489, by the homology alignment algorithm of Needleman and Wunsch (1970) J. Mol. Biol. 48:443-453, by the search for similarity method of Pearson and Lipman (1988) Proc. Nat'l. Acad. Sci. USA 85:2444-2448, by computerized implementations of these algorithms (GAP, BESTFIT, FASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group, 575 Science Dr., Madison, WI), or by manual alignment and visual inspection (see, e.g., Ausubel, et al. (eds. 1995 and supplements) Current Protocols in Molecular Biology Wiley).
  • BLAST and BLAST 2.0 are used, with the parameters described herein, to determine percent sequence identity for the nucleic acids and proteins of the invention.
  • Software for performing BLAST analyses is publicly available through the National Center for Biotechnology Information (http://www.ncbi.nlm.nih.gov/).
  • This algorithm involves first identifying high scoring sequence pairs (HSPs) by identifying short words of length W in the query sequence, which either match or satisfy some positive-valued threshold score T when aligned with a word of the same length in a database sequence. T is referred to as the neighborhood word score threshold (Altschul, et al., supra). These initial neighborhood word hits act as seeds for initiating searches to find longer HSPs containing them. The word hits are extended in both directions along each sequence for as far as the cumulative alignment score can be increased.
  • HSPs high scoring sequence pairs
  • Cumulative scores are calculated using, e.g., for nucleotide sequences, the parameters M (reward score for a pair of matching residues; always > 0) and N (penalty score for mismatching residues; always ⁇ 0).
  • M forward score for a pair of matching residues; always > 0
  • N penalty score for mismatching residues; always ⁇ 0.
  • a scoring matrix is used to calculate the cumulative score. Extension of the word hits in each direction are halted when: the cumulative alignment score falls off by the quantity X from its maximum achieved value; the cumulative score goes to zero or below, due to the accumulation of one or more negative- scoring residue alignments; or the end of either sequence is reached.
  • the BLAST algorithm parameters W, T, and X determine the sensitivity and speed of the alignment.
  • W wordlength
  • E expectation
  • the BLAST algorithm also performs a statistical analysis of the similarity between two sequences. See, e.g., Karlin and Altschul (1993) Proc. Nat'l. Acad. Sci. USA 90:5873-5787.
  • One measure of similarity provided by the BLAST algorithm is the smallest sum probability (P(N)), which provides an indication of the probability by which a match between two nucleotide or amino acid sequences would occur by chance.
  • P(N) the smallest sum probability
  • a nucleic acid is considered similar to a reference sequence if the smallest sum probability in a comparison of the test nucleic acid to the reference nucleic acid is less than about 0.2, more preferably less than about 0.01, and most preferably less than about 0.001.
  • Log values may be negative large numbers, e.g., 5, 10, 20, 30, 40, 40, 70, 90, 110, 150, 170, etc.
  • nucleic acid sequences are substantially identical.
  • a polypeptide is typically substantially identical to a second polypeptide, e.g., where the two peptides differ only by conservative substitutions.
  • Another indication that two nucleic acid sequences are substantially identical is that the two molecules or their complements hybridize to each other under stringent conditions.
  • Yet another indication that two nucleic acid sequences are substantially identical is that the same primers can be used to amplify the sequences.
  • a "host cell” is a naturally occurring cell or a transformed cell that contains an expression vector and supports the replication or expression of the expression vector.
  • Host cells may be cultured cells, explants, cells in vivo, and the like.
  • Host cells may be prokaryotic cells such as E. coli, or eukaryotic cells such as yeast, insect, amphibian, or mammalian cells such as CHO, HeLa, and the like (see, e.g., the American Type Culture Collection catalog or web site, www.atcc.org).
  • isolated refers to material that is substantially or essentially free from components that normally accompany it as found in its native state. Purity and homogeneity are typically determined using analytical chemistry techniques such as polyacrylamide gel electrophoresis or high performance liquid chromatography. A protein or nucleic acid that is the predominant species present in a preparation is substantially purified. In particular, an isolated nucleic acid is separated from some open reading frames that naturally flank the gene and encode proteins other than protein encoded by the gene.
  • purified in some embodiments denotes that a nucleic acid or protein gives rise to essentially one band in an electrophoretic gel.
  • nucleic acid or protein is at least about 85% pure, more preferably at least 95% pure, and most preferably at least 99% pure.
  • “Purify” or “purification” in other embodiments means removing at least one contaminant or component from the composition to be purified. In this sense, purification does not require that the purified compound be homogeneous, e.g., 100% pure.
  • polypeptide polypeptide
  • peptide and “protein” are used interchangeably herein to refer to a polymer of amino acid residues. The terms apply to amino acid polymers in which one or more amino acid residue is an artificial chemical mimetic of a corresponding naturally occurring amino acid, as well as to naturally occurring amino acid polymers, those containing modified residues, and non-naturally occurring amino acid polymers.
  • amino acid refers to naturally occurring and synthetic amino acids, as well as amino acid analogs and amino acid mimetics that function similarly to the naturally occurring amino acids.
  • Naturally occurring amino acids are those encoded by the genetic code, as well as those amino acids that are later modified, e.g., hydroxyproline, ⁇ -carboxyglutamate, and O- phosphoserine.
  • Amino acid analogs refers to compounds that have the same basic chemical structure as a naturally occurring amino acid, e.g., an carbon that is bound to a hydrogen, a carboxyl group, an amino group, and an R group, e.g., homoserine, norleucine, methionine sulfoxide, methionine methyl sulfonium.
  • Such analogs may have modified R groups (e.g., norleucine) or modified peptide backbones, but retain somebasic chemical structure as a naturally occurring amino acid.
  • Amino acid mimetic refers to a chemical compound that has a structure that is different from the general chemical structure of an amino acid, but that functions similarly to another amino acid.
  • nucleotides likewise, may be referred to by their commonly accepted single-letter codes.
  • Constantly modified variant applies to both amino acid and nucleic acid sequences. With respect to particular nucleic acid sequences, conservatively modified variants refers to those nucleic acids which encode identical or essentially identical amino acid sequences, or where the nucleic acid does not encode an amino acid sequence, to essentially identical or associated, e.g., naturally contiguous, sequences. Because of the degeneracy of the genetic code, a large number of functionally identical nucleic acids encode most proteins. For instance, the codons GCA, GCC, GCG, and GCU each encode the amino acid alanine.
  • nucleic acid variations are "silent variations," which are one species of conservatively modified variations.
  • Every nucleic acid sequence herein which encodes a polypeptide also describes silent variations of the nucleic acid.
  • each codon in a nucleic acid except AUG, which is ordinarily the only codon for methionine, and TGG, which is ordinarily the only codon for tryptophan
  • TGG which is ordinarily the only codon for tryptophan
  • amino acid sequences one of skill will recognize that individual substitutions, deletions, or additions to a nucleic acid, peptide, polypeptide, or protein sequence which alters, adds, or deletes a single amino acid or a small percentage of amino acids in the encoded sequence is a "conservatively modified variant" where the alteration results in the substitution of an amino acid with a chemically similar amino acid. Conservative substitution tables providing functionally similar amino acids are well known. Such conservatively modified variants are in addition to and do not exclude polymo ⁇ hic variants, interspecies homologs, and alleles of the invention.
  • conservative substitutions include for one another: 1) Alanine (A), Glycine (G); 2) Aspartic acid (D), Glutamic acid (E); 3) Asparagine (N), Glutamine (Q); 4) Arginine (R), Lysine (K); 5) Isoleucine (I), Leucine (L), Methionine (M), Valine (V); 6) Phenylalanine (F), Tyrosine (Y), Tryptophan (W); 7) Serine (S), Threonine (T); and 8) Cysteine (C), Methionine (M) (see, e.g., Creighton (1984) Proteins: Structure and Molecular Properties Freeman).
  • Macromolecular structures such as polypeptide structures can be described in terms of various levels of organization. For a general discussion of this organization, see, e.g., Alberts, ( et al. (eds. 2001) Molecular Biology of the Cell (4th ed.) Garland; and Cantor and Schimmel
  • “Secondary structure” refers to locally ordered, three dimensional structures within a polypeptide. These structures are commonly known as domains. Domains are portions of a polypeptide that often form a compact unit of the polypeptide and are typically 25 to approximately 500 amino acids long. Typical domains are made up of sections of lesser organization such as stretches of ⁇ -sheet and ⁇ -helices. "Tertiary structure” refers to the complete three dimensional structure of a polypeptide monomer. "Quaternary structure” refers to the three dimensional structure formed, usually by the noncovalent association of independent tertiary units. Anisotropic terms are also known as energy terms.
  • Nucleic acid or “oligonucleotide” or “polynucleotide” or grammatical equivalents used herein means at least two nucleotides covalently linked together. Oligonucleotides are typically from about 5, 6, 7, 8, 9, 10, 12, 15, 25, 30, 40, 50, or more nucleotides in length, up to about 100 nucleotides in length. Nucleic acids and polynucleotides are a polymers of any length, including longer lengths, e.g., 200, 300, 500, 1000, 2000, 3000, 5000, 7000, 10,000, etc.
  • a nucleic acid of the present invention will generally contain phosphodiester bonds, although in some cases, nucleic acid analogs are included that may have at least one different linkahge, e.g., phosphoramidate, phosphorothioate, phosphorodithioate, or O-methylphophoroamidite linkages (see Eckstein (1992) Oligonucleotides and Analogues: A Practical Approach Oxford Univ. Press); and peptide nucleic acid backbones and linkages.
  • Other analog nucleic acids include those with positive backbones; non-ionic backbones, and non-ribose backbones, including those described in U.S. Patent Nos.
  • nucleic acids containing one or more carbocyclic sugars are also included within one definition of nucleic acids. Modifications of the ribose-phosphate backbone may be done for a variety of reasons, e.g., to increase the stability and half-life of such molecules in physiological environments or as probes on a biochip. Mixtures of naturally occurring nucleic acids and analogs can be made; alternatively, mixtures of different nucleic acid analogs, and mixtures of naturally occurring nucleic acids and analogs may be made.
  • nucleic acid analogs including, e.g., phosphoramidate (Beaucage, et al. (1993) Tetrahedron 49:1925-1963 and references therein; Letsinger (1970) J. Org. Chem. 35:3800-3803; Sblul, et al. (1977) Eur. J. Biochem. 81:579- 589; Letsinger, et al. (1986) Nucl. Acids Res. 14:3487-499; Sawai, et al. (1984) Chem. Lett. 805, Letsinger, et al. (1988) J. Am. Chem. Soc.
  • nucleic acids containing one or more carbocyclic sugars are also included within one definition of nucleic acids (see Jenkins, et al. (1995) Chem. Soc. Rev, pp 169-176). Several nucleic acid analogs are described in Rawls (page 35, June 2, 1997) C&E News.
  • PNA peptide nucleic acids
  • These backbones are substantially non-ionic under neutral conditions, in contrast to the highly charged phosphodiester backbone of naturally occurring nucleic acids. This results in at least two advantages.
  • the PNA backbone exhibits improved hybridization kinetics. PNAs have larger changes in the melting temperature (T m ) for mismatched versus perfectly matched basepairs. DNA and RNA typically exhibit a 2-4° C drop in T m for an internal mismatch. With the non-ionic PNA backbone, the drop is closer to 7-9° C.
  • PNAs are not degraded by cellular enzymes, and thus can be more stable.
  • the nucleic acids may be single stranded or double stranded, as specified, or contain portions of both double stranded or single stranded sequence.
  • the depiction of a single strand also defines the sequence of the complementary strand; thus the sequences described herein also provide the complement of the sequence.
  • the nucleic acid may be DNA, both genomic and cDNA, RNA, or a hybrid, where the nucleic acid may contain combinations of deoxyribo- and ribo-nucleotides, and combinations of bases, including uracil, adenine, thymine, cytosine, guanine, inosine, xanthine hypoxanthine, isocytosine, isoguanine, etc.
  • Transcript typically refers to a naturally occurring RNA, e.g., a pre-mRNA, hnRNA, or mRNA.
  • nucleoside includes nucleotides and nucleoside and nucleotide analogs, and modified nucleosides such as amino modified nucleosides.
  • nucleoside includes non-natural occurring analog structures. Thus, e.g., the individual units of a peptide nucleic acid, each containing a base, are referred to herein as a nucleoside.
  • a “label” or a “detectable moiety” is a composition detectable by spectroscopic, photochemical, biochemical, immunochemical, physiological, chemical, or other physical means.
  • labels fall into three classes: a) isotopic labels, which may be radioactive or heavy isotopes; b) immune labels, which may be antibodies, antigens, or epitope tags; and c) colored or fluorescent dyes.
  • the labels may be inco ⁇ orated into the cancer nucleic acids, proteins, and antibodies.
  • the label should be capable of producing, either directly or indirectly, a detectable signal.
  • the detectable moiety may be a radioisotope, such as ⁇ H, 14c, 32p s 35 ⁇ 5 or 125j 5 electron-dense reagents, a fluorescent or chemiluminescent compound, such as fluorescein isothiocyanate, rhodamine, or luciferin, or an enzyme (e.g., as commonly used in an ELISA), biotin, digoxigenin, or haptens and proteins or other entities which can be made detectable such as alkaline phosphatase, beta-galactosidase, or horseradish peroxidase. Methods are known for conjugating the antibody to the label. See, e.g., Hunter, et al.
  • effector or “effector moiety” or “effector component” is a molecule that is bound (or linked, or conjugated), either covalently, through a linker or a chemical bond, or noncovalently, through ionic, van der Waals, electrostatic, or hydrogen bonds, to an antibody.
  • the "effector” can be a variety of molecules including, e.g., detection moieties including radioactive compounds, fluorescent compounds, enzymes or substrates, tags such as epitope tags, toxins; activatable moieties, chemotherapeutic agents; lipases; antibiotics; chemoattracting moieties, immune modulators (micA/B), or radioisotopes, e.g., emitting "hard” beta, radiation.
  • a "labeled nucleic acid probe or oligonucleotide” is one that is bound, e.g., covalently, through a linker or a chemical bond, or noncovalently, through ionic, van der Waals, electrostatic, or hydrogen bonds to a label such that the presence of the probe may be detected by detecting the presence of the label bound to the probe.
  • methods using high affinity interactions may achieve the same results where one of a pair of binding partners binds to the other, e.g., biotin, streptavidin.
  • nucleic acid probe or oligonucleotide is a nucleic acid capable of binding to a target nucleic acid of complementary sequence through one or more types of chemical bonds, usually through complementary base pairing, e.g., through hydrogen bond formation.
  • a probe may include natural (e.g., A, G, C, or T) or modified bases (7-deazaguanosine, inosine, etc.).
  • the bases in a probe may be joined by a linkage other than a phosphodiester bond, preferably one that does not functionally interfere with hybridization.
  • probes may be peptide nucleic acids in which the constituent bases are joined by peptide bonds rather than phosphodiester linkages. Probes may bind target sequences lacking complete complementarity with the probe sequence depending upon the stringency of the hybridization conditions.
  • the probes are preferably directly labeled, e.g., with isotopes, chromophores, lumiphores, chromogens, or indirectly labeled, e.g., with biotin to which a streptavidin complex may later bind. By assaying for the presence or absence of the probe, one can detect the presence or absence of the select sequence or subsequence.
  • Diagnosis or prognosis may be based at the genomic level, or at the level of RNA or protein expression.
  • the term "recombinant" when used with reference, e.g., to a cell, or nucleic acid, protein, or vector, indicates that the cell, nucleic acid, protein, or vector, has been modified by the introduction of a heterologous nucleic acid or protein or the alteration of a native nucleic acid or protein, or that the cell is derived from a cell so modified.
  • recombinant cells express genes that are not found within the native (non-recombinant) form of the cell or express native genes that are otherwise abnormally expressed, under expressed, or not expressed at all.
  • nucleic acid By the term “recombinant nucleic acid” herein is meant nucleic acid, originally formed in vitro, in general, by the manipulation of nucleic acid, e.g., using polymerases and endonucleases, in a form not normally found in nature. In this manner, operably linkage of different sequences is achieved.
  • an isolated nucleic acid, in a linear form, or an expression vector formed in vitro by ligating DNA molecules that are not normally joined are both considered recombinant for the pu ⁇ oses of this invention.
  • nucleic acid once a recombinant nucleic acid is made and reintroduced into a host cell or organism, it will replicate non-recombinantly, e.g., using the in vivo cellular machinery of the host cell rather than in vitro manipulations; however, such nucleic acids, once produced recombinantly, although subsequently replicated non- recombinantly, are still considered recombinant for the pu ⁇ oses of the invention.
  • a "recombinant protein” is a protein made using recombinant techniques, e.g., through the expression of a recombinant nucleic acid as depicted above.
  • a recombinant protein is distinguished from naturally occurring protein by at least one or more characteristics.
  • the protein may be isolated or purified away from some or most of the proteins and compounds with which it is normally associated in its wild type host, and thus may be substantially pure.
  • An isolated protein is unaccompanied by at least some of the material with which it is normally associated in its natural state, preferably constituting at least about 0.5%, more preferably at least about 5% by weight of the total protein in a given sample.
  • a substantially pure protein comprises at least about 75% by weight of the total protein, with at least about 80% being preferred, and at least about 90% being particularly preferred.
  • the definition includes the production of a cancer protein from one organism in a different organism or host cell.
  • the protein may be made at a significantly higher concentration than is normally seen, through the use of an inducible promoter or high expression promoter, such that the protein is made at increased concentration levels.
  • the protein may be in a form not normally found in nature, as in the addition of an epitope tag or amino acid substitutions, insertions and deletions, as discussed below.
  • heterologous when used with reference to portions of a nucleic acid indicates that the nucleic acid comprises two or more subsequences that are not normally found in the same relationship to each other in nature.
  • the nucleic acid is typically recombinantly produced, having two or more sequences, e.g., from unrelated genes arranged to make a new functional nucleic acid, e.g., a promoter from one source and a coding region from another source.
  • a heterologous protein will often refer to two or more subsequences that are not found in the same relationship to each other in nature (e.g., a fusion protein).
  • a “promoter” is typically an array of nucleic acid control sequences that direct transcription of a nucleic acid.
  • a promoter includes necessary nucleic acid sequences near the start site of transcription, such as, in the case of a polymerase II type promoter, a TATA element.
  • a promoter also optionally includes distal enhancer or repressor elements, which can be located as much as several thousand base pairs from the start site of transcription.
  • a “constitutive” promoter is a promoter that is active under most environmental and developmental conditions.
  • An “inducible” promoter is active under environmental or developmental regulation.
  • operably linked refers to a functional linkage between a nucleic acid expression control sequence (such as a promoter, or array of transcription factor binding sites) and a second nucleic acid sequence, e.g., wherein the expression control sequence directs transcription of the nucleic acid corresponding to the second sequence.
  • An "expression vector” is a nucleic acid construct, generated recombinantly or synthetically, with a series of specified nucleic acid elements that permit transcription of a particular nucleic acid in a host cell.
  • the expression vector can be part of a plasmid, virus, or nucleic acid fragment.
  • the expression vector includes a nucleic acid to be transcribed in operable linkage to a promoter.
  • stringent hybridization conditions refers to conditions under which a probe will hybridize to its target subsequence, typically in a complex mixture of nucleic acids, but to no other sequences. Stringent conditions are sequence-dependent and will be different in different circumstances. Longer sequences hybridize specifically at higher temperatures. An extensive guide to the hybridization of nucleic acids is found in "Overview of principles of hybridization and the strategy of nucleic acid assays” in Tijssen (1993) Hybridization with Nucleic Probes (Laboratory Techniques in Biochemistry and Molecular Biology) (vol. 24) Elsevier. Generally, stringent conditions are selected to be about 5-10° C lower than the thermal melting point (T m ) for the specific sequence at a defined ionic strength pH.
  • T m thermal melting point
  • the T m is the temperature (under defined ionic strength, pH, and nucleic concentration) at which 50% of the probes complementary to the target hybridize to the target sequence at equilibrium (as the target sequences are present in excess, at T m , 50% of the probes are occupied at equilibrium).
  • Stringent conditions will be those in which the salt concentration is less than about 1.0 M sodium ion, typically about 0.01-1.0 M sodium ion concentration (or other salts) at pH 7.0 to 8.3 and the temperature is at least about 30° C for short probes (e.g., about 10-50 nucleotides) and at least about 60° C for long probes (e.g., greater than about 50 nucleotides). Stringent conditions may also be achieved with the addition of destabilizing agents such as formamide. For selective or specific hybridization, a positive signal is typically at least two times background, preferably 10 times background hybridization.
  • Exemplary stringent hybridization conditions can be as following: 50% formamide, 5x SSC, and 1% SDS, incubating at 42° C, or, 5x SSC, 1% SDS, incubating at 65° C, with wash in 0.2x SSC, and 0.1% SDS at 65° C.
  • a temperature of about 36° C is typical for low stringency amplification, although annealing temperatures may vary between about 32°-48° C depending on primer length.
  • a temperature of about 62° C is typical, although high stringency annealing temperatures can range from about 50-65° C, depending on the primer length and specificity.
  • Typical cycle conditions for both high and low stringency amplifications include a denaturation phase of 90-95° C for 30-120 sec, an annealing phase lasting 30-120 sec, and an extension phase of about 72° C for 1-2 min. Protocols and guidelines for low and high stringency amplification reactions are provided, e.g., in Innis, et al. (1990) PCR Protocols: A Guide to Methods and Applications Academic Press, NY.
  • Nucleic acids that do not hybridize to each other under stringent conditions are still substantially identical if the polypeptides which they encode are substantially identical. This occurs, e.g., when a copy of a nucleic acid is created using the maximum codon degeneracy permitted by the genetic code. In such cases, the nucleic acids typically hybridize under moderately stringent hybridization conditions.
  • Exemplary "moderately stringent hybridization conditions" include a hybridization in a buffer of 40% formamide, 1 M NaCl, 1% SDS at 37° C, and a wash in IX SSC at 45° C. A positive hybridization is typically at least twice background. Alternative hybridization and wash conditions can be utilized to provide conditions of similar stringency. Additional guidelines for determining hybridization parameters are provided in numerous references, e.g., Ausubel, et al. (eds. 1991 and supplements) Current Protocols in Molecular Biology Wiley.
  • the phrase "functional effects" in the context of assays for testing compounds that modulate activity of a cancer protein includes the determination of a parameter that is indirectly or directly under the influence of the cancer protein or nucleic acid, e.g., a physiological, functional, physical, or chemical effect, such as the ability to decrease cancer. It includes ligand binding activity; cell viability; cell growth on soft agar; anchorage dependence; contact inhibition and density limitation of growth; cellular proliferation; cellular transformation; growth factor or serum dependence; tumor specific marker levels; invasiveness into Matrigel; tumor growth and metastasis in vivo; mRNA and protein expression in cells undergoing metastasis; and other characteristics of cancer cells. "Functional effects” include in vitro, in vivo, and ex vivo activities.
  • determining the functional effect is meant assaying for a compound that increases or decreases a parameter that is indirectly or directly under the influence of a cancer protein sequence, e.g., physiological, functional, enzymatic, physical, or chemical effects.
  • Such functional effects can be measured, e.g., changes in spectroscopic characteristics (e.g., fluorescence, absorbance, refractive index), hydrodynamic (e.g., shape), chromatographic, or solubility properties for the protein, measuring inducible markers or transcriptional activation of the cancer protein, measuring binding activity or binding assays, e.g., binding to antibodies or other ligands, and measuring growth, cellular proliferation, cell viability, cellular transformation, growth factor or serum dependence, tumor specific marker levels, invasiveness into Matrigel, tumor growth and metastasis in vivo, mRNA and protein expression, and other characteristics of cancer cells.
  • spectroscopic characteristics e.g., fluorescence, absorbance, refractive index
  • hydrodynamic e.g
  • the functional effects can be evaluated by many means, e.g., microscopy for quantitative or qualitative measures of alterations in mo ⁇ hological features, measurement of changes in RNA or protein levels for cancer-associated sequences, measurement of RNA stability, identification of downstream or reporter gene expression (CAT, luciferase, /3-gal, GFP, and the like), e.g., via chemiluminescence, fluorescence, colorimetric reactions, antibody binding, inducible markers, and ligand binding assays.
  • microscopy for quantitative or qualitative measures of alterations in mo ⁇ hological features
  • measurement of changes in RNA or protein levels for cancer-associated sequences e.g., measurement of changes in RNA or protein levels for cancer-associated sequences
  • RNA stability e.g., identification of downstream or reporter gene expression (CAT, luciferase, /3-gal, GFP, and the like), e.g., via chemiluminescence, fluorescence, colorimetric reactions, antibody binding, inducible markers, and
  • Inhibitors are used to refer to activating, inhibitory, or modulating molecules or compounds identified using in vitro and in vivo assays of cancer polynucleotide and polypeptide sequences.
  • Inhibitors are compounds that, e.g., bind to, partially or totally block activity, decrease, prevent, delay activation, inactivate, desensitize, or down regulate the activity or expression of cancer proteins, e.g., antagonists.
  • Antisense or inhibitory nucleic acids may seem to inhibit expression and subsequent function of the protein.
  • Activators are compounds that increase, open, activate, facilitate, enhance activation, sensitize, agonize, or up regulate cancer protein activity.
  • Inhibitors, activators, or modulators also include genetically modified versions of cancer proteins, e.g., versions with altered activity, as well as naturally occurring and synthetic ligands, antagonists, agonists, antibodies, small chemical molecules, and the like.
  • Such assays for inhibitors and activators include, e.g., expressing the cancer protein in vitro, in cells, or cell membranes, applying putative modulator compounds, and then determining the functional effects on activity, as described above.
  • Activators and inhibitors of cancer can also be identified by incubating cancer cells with the test compound and determining increases or decreases in the expression of 1 or more cancer proteins, e.g., 1, 2, 3, 4, 5, 10, 15, 20, 25, 30, 40, 50, or more cancer proteins, such as cancer proteins encoded by the sequences set out in Tables 2A-80.
  • 1 or more cancer proteins e.g., 1, 2, 3, 4, 5, 10, 15, 20, 25, 30, 40, 50, or more cancer proteins, such as cancer proteins encoded by the sequences set out in Tables 2A-80.
  • Samples or assays comprising cancer proteins that are treated with a potential activator, inhibitor, or modulator are compared to control samples without the inhibitor, activator, or modulator to examine the extent of inhibition.
  • Control samples (untreated with inhibitors) are assigned a relative protein activity value of 100%.
  • Inhibition of a polypeptide is achieved when the activity value relative to the control is about 80%, preferably 50%, more preferably 25-0%.
  • Activation of a cancer polypeptide is achieved when the activity value relative to the control (untreated with activators) is about 110%, more preferably 150%, more preferably 200-500% (e.g., two to five fold higher relative to the control), more preferably 1000-3000% higher.
  • change in cell growth refers to any change in cell growth and proliferation characteristics in vitro or in vivo, such as cell viability, formation of foci, anchorage independence, semi-solid or soft agar growth, changes in contact inhibition and density limitation of growth, loss of growth factor or serum requirements, changes in cell mo ⁇ hology, gaining or losing immortalization, gaining or losing tumor specific markers, ability to form or suppress tumors when injected into suitable animal hosts, and/or immortalization of the cell.
  • Tumor cell refers to precancerous, cancerous, and normal cells in a tumor.
  • Cancer cells “transformed” cells or “transformation” in tissue culture, refers to spontaneous or induced phenotypic changes that do not necessarily involve the uptake of new genetic material. Although transformation can arise from infection with a transforming virus and inco ⁇ oration of new genomic DNA, or uptake of exogenous DNA, it can also arise spontaneously or following exposure to a carcinogen, thereby mutating an endogenous gene. Transformation is associated with phenotypic changes, such as immortalization of cells, aberrant growth control, nonmo ⁇ hological changes, and/or malignancy.
  • Antibody refers to a polypeptide comprising a framework region from an immunoglobulin gene or fragments thereof that specifically binds and recognizes an antigen.
  • the recognized immunoglobulin genes include the kappa, lambda, alpha, gamma, delta, epsilon, and mu constant region genes, as well as the myriad immunoglobulin variable region genes. Light chains are classified as either kappa or lambda.
  • Heavy chains are classified as gamma, mu, alpha, delta, or epsilon, which in turn define the immunoglobulin classes, IgG, IgM, IgA, IgD, and IgE, respectively.
  • IgG, IgM, IgA, IgD, and IgE immunoglobulin classes
  • An exemplary immunoglobulin (antibody) structural unit comprises a tetramer. Each tetramer is composed of two identical pairs of polypeptide chains, each pair having one "light” (about 25 kD) and one "heavy” chain (about 50-70 kD). The N-terminus of each chain defines a variable region of about 100 to 110 or more amino acids primarily responsible for antigen recognition.
  • the terms variable light chain (Nj_) and variable heavy chain (VJJ) refer to these light and heavy chains respectively.
  • Antibodies exist, e.g., as intact immunoglobulins or as a number of well-characterized fragments produced by digestion with various peptidases.
  • pepsin digests an antibody below the disulfide linkages in the hinge region to produce F(ab)*2 a dimer of Fab which itself is a light chain joined to VJJ-CJJI by a disulfide bond.
  • the F(ab)'2 may be reduced under mild conditions to break the disulfide linkage in the hinge region, thereby converting the F(ab)*2 dimer into an Fab' monomer.
  • the Fab 1 monomer is essentially Fab with part of the hinge region (see Paul (ed.
  • antibody fragments are defined in terms of the digestion of an intact antibody, one of skill will appreciate that such fragments may be synthesized de novo either chemically or by using recombinant D ⁇ A methodology.
  • the term antibody also includes antibody fragments either produced by the modification of whole antibodies, or those synthesized de novo using recombinant D ⁇ A methodologies (e.g., single chain Fv) or those identified using phage display libraries (see, e.g., McCafferty, et al. (1990) Nature 348:552-554).
  • phage display technology can be used to identify antibodies and heteromeric Fab fragments that specifically bind to selected antigens. See, e.g., McCafferty, et al. (1990) Nature 348:552-554; Marks, et al. (1992) Biotechnology 10:779-783.
  • a "chimeric antibody” is an antibody molecule in which (a) the constant region, or a portion thereof, is altered, replaced, or exchanged so that the antigen binding site (variable region) is linked to a constant region of a different or altered class, and/or species, or an entirely different molecule which confers new properties to the chimeric antibody, e.g., an enzyme, toxin, hormone, growth factor, drug, effector function, chemoattractant, immune modulator, etc.; or (b) the variable region, or a portion thereof, is altered, replaced, or exchanged with a variable region having a different or altered antigen specificity.
  • the expression levels of genes are determined in different patient samples for which diagnosis information is desired, to provide expression profiles.
  • An expression profile of a particular sample is essentially a "finge ⁇ rint" of the state of the sample; while two states may have any particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is characteristic of the state of the cell. That is, normal tissue may be distinguished from cancerous or metastatic cancerous tissue, or cancer tissue or metastatic cancerous tissue can be compared with tissue from surviving cancer patients. By comparing expression profiles of tissue in known different cancer states, information regarding which genes are important (including both up-and down- regulation of genes) in each of these states is obtained. Molecular profiling may distinguish subtypes of a currently collective disease designation, e.g., different forms of a cancer.
  • sequences that are differentially expressed in cancer versus non- cancer tissue allows the use of this information in a number of ways. For example, a particular treatment regime may be evaluated: does a chemotherapeutic drug act to down-regulate cancer, and thus tumor growth or recurrence, in a particular patient. Alternatively, a treatment step may induce other markers which may be used as targets to destroy tumor cells. Similarly, diagnosis and treatment outcomes may be done or confirmed by comparing patient samples with the known expression profiles. Maliganant disease may be compared to non-malignant conditions. Metastatic tissue can also be analyzed to determine the stage of cancer in the tissue, or origin of primary tumor, e.g., metastasis from a remote primary site.
  • these gene expression profiles allow screening of drug candidates with an eye to mimicking or altering a particular expression profile; e.g., screening can be done for drugs that suppress the cancer expression profile. This may be done by making biochips comprising sets of the important cancer genes, which can then be used in these screens. These methods can also be done on the protein basis; that is, protein expression levels of the cancer proteins can be evaluated for diagnostic pu ⁇ oses or to screen candidate agents.
  • the cancer nucleic acid sequences can be administered for gene therapy pu ⁇ oses, including the administration of antisense nucleic acids, or the cancer proteins (including antibodies and other modulators thereof) administered as therapeutic drugs.
  • cancer sequences include those that are up-regulated (e.g., expressed at a higher level) in cancer, as well as those that are down-regulated (e.g., expressed at a lower level).
  • the cancer sequences are from humans; however, cancer sequences from other organisms may be useful in animal models of disease and drug evaluation; thus, other cancer sequences are provided, from vertebrates, including mammals, including rodents (rats, mice, hamsters, guinea pigs, etc.), primates, farm animals (including sheep, goats, pigs, cows, horses, etc.) and pets (e.g., dogs, cats, etc.). Cancer sequences from other organisms may be obtained using the techniques outlined below. Cancer sequences can include both nucleic acid and amino acid sequences. In a preferred embodiment, the skin cancer sequences are recombinant nucleic acids.
  • nucleic acid sequences are useful in a variety of applications, including diagnostic applications, which will detect naturally occurring nucleic acids, as well as screening applications; e.g., biochips comprising nucleic acid probes or PCR microtiter plates with selected probes to the cancer sequences.
  • a cancer sequence can be initially identified by substantial nucleic acid and/or amino acid sequence homology to the cancer sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, e.g., using homology programs or hybridization conditions.
  • the cancer screen typically includes comparing genes identified in different tissues, e.g., normal and cancerous tissues, cancer and non-malignant conditions, non-malignant conditions and normal tissues, or tumor tissue samples from patients who have metastatic disease vs. non metastatic tissue.
  • Other suitable tissue comparisons include comparing cancer samples with metastatic cancer samples from other cancers, such as lung, stomach, gastrointestinal cancers, etc.
  • Samples of different stages of cancer e.g., survivor tissue, drug resistant states, and tissue undergoing metastasis, are applied to biochips comprising nucleic acid probes. The samples are first microdissected, if applicable, and treated for preparation of mRNA.
  • Suitable biochips are commercially available, e.g., from Affymetrix, Santa Clara, CA. Gene expression profiles as described herein are generated and the data analyzed.
  • the genes showing changes in expression as between normal and disease states are compared to genes expressed in other normal tissues, including, and not limited to lung, heart, brain, liver, stomach, kidney, muscle, colon, small intestine, large intestine, spleen, bone, and/or placenta.
  • those genes identified during the cancer screen that are expressed in a significant amount in other tissues are removed from the profile, although in some embodiments, this is not necessary (e.g., where organs may be dispensible, e.g., female or male specific). That is, when screening for drugs, it is usually preferable that the target expression be disease specific, to minimize possible side effects on other organs were there expression.
  • cancer sequences are those that are up-regulated in cancer; that is, the expression of these genes is higher in the cancer tissue as compared to non-cancer or non-malignant tissue.
  • Up-regulation as used herein often means at least about a two-fold change, preferably at least about a three fold change, with at least about five-fold or higher being preferred.
  • Another embodiment is directed to sequences up-regulated in non-malignant conditions relative to normal. Uniformity among relevant samples is also preferred.
  • Unigene cluster identification numbers and accession numbers herein are for the GenBank sequence database and the sequences of the accession numbers are hereby expressly inco ⁇ orated by reference.
  • GenBank is available, see, e.g., Benson, et al. (1998) Nuc. Acids Res. 26:1-7; and http://www.ncbi.nlm.nih.gov/.
  • Sequences are also available in other databases, e.g., European Molecular Biology Laboratory (EMBL) and DNA Database of Japan (DDBJ).
  • the sequences may be derived from assembly of available sequences or be predicted from genomic DNA using exon prediction algorithms, such as FGENESH. See Salamov and Solovyev (2000) Genome Res. 10:516-522.
  • sequences have been derived from cloning and sequencing of isolated nucleic acids.
  • cancer sequences are those that are down-regulated in the cancer; that is, the expression of these genes is lower in cancer tissue as compared to non- cancerous tissue.
  • Down-regulation as used herein often means at least about a two-fold change, preferably at least about a three fold change, with at least about five-fold or higher being preferred.
  • the ability to identify genes that are over or under expressed in cancer can additionally provide high-resolution, high-sensitivity datasets which can be used in the areas of diagnostics, therapeutics, drug development, pharmacogenetics, protein structure, biosensor development, and other related areas.
  • the expression profiles can be used in diagnostic or prognostic evaluation of patients with cancer or related diseases. See Tables 1-3.
  • subcellular toxicological information can be generated to better direct drug structure and activity correlation (see Anderson (June 11-12, 1998) Pharmaceutical Proteomics: Targets, Mechanism, and Function, paper presented at the JJ3C Proteomics conference, Coronado, CA).
  • Subcellular toxicological information can also be utilized in a biological sensor device to predict the likely toxicological effect of chemical exposures and likely tolerable exposure thresholds (see U.S. Patent No. 5,811,231). Similar advantages accrue from datasets relevant to other biomolecules and bioactive agents (e.g., nucleic acids, saccharides, lipids, drugs, and the like).
  • the present invention provides a database that includes at least one set of assay data.
  • the data contained in the database is acquired, e.g., using array analysis either singly or in a library format.
  • the database can be in a form in which data can be maintained and transmitted, but is preferably an electronic database.
  • the electronic database of the invention can be maintained on any electronic device allowing for the storage of and access to the database, such as a personal computer, but is preferably distributed on a wide area network, such as the World Wide Web.
  • the focus of the present section on databases that include peptide sequence data is for clarity of illustration only. Similar databases can be assembled for assay data acquired using an assay of the invention.
  • compositions and methods for identifying and/or quantitating the relative and/or absolute abundance of a variety of molecular and macromolecular species from a biological sample representing cancer e.g., the identification of cancer-associated sequences described herein, provide an abundance of information which can be correlated with pathological conditions, predisposition to disease, drug testing, therapeutic monitoring, gene-disease causal linkages, identification of correlates of immunity and physiological status, among others.
  • data generated from the assays of the invention is suited for manual review and analysis, in a preferred embodiment, data processing using high-speed computers is utilized.
  • U.S. Patents 6,023,659 and 5,966,712 disclose a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to one or more protein function hierarchies.
  • U.S. Patent 5,953,727 discloses a relational database having sequence records containing information in a format that allows a collection of partial-length DNA sequences to be catalogued and searched according to association with one or more sequencing projects for obtaining full-length sequences from the collection of partial length sequences.
  • Patent 5,706,498 discloses a gene database retrieval system for making a retrieval of a gene sequence similar to a sequence data item in a gene database based on the degree of similarity between a key sequence and a target sequence.
  • U.S. Patent 5,538,897 discloses a method using mass spectroscopy fragmentation patterns of peptides to identify amino acid sequences in computer databases by comparison of predicted mass spectra with experimentally-derived mass spectra using a closeness-of-fit measure.
  • U.S. Patent 5,926,818 discloses a multi-dimensional database comprising a functionality for multidimensional data analysis described as on-line analytical processing (OLAP), which entails the consolidation of projected and actual data according to more than one consolidation path or dimension.
  • OLAP on-line analytical processing
  • Patent 5,295,261 reports a hybrid database structure in which the fields of each database record are divided into two classes, navigational and informational data, with navigational fields stored in a hierarchical topological map which can be viewed as a tree structure or as the merger of two or more such tree structures. See also Baxevanis, et al. (2001) Bioinformatics: A Practical Guuide to the Analysis of Genes and Proteins Wiley; Mount (2001) Bioinformatics: Sequence and Genome Analysis CSH Press, NY; Durbin, et al. (eds. 1999) Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids Cambridge University Press; Baxevanis and Oeullette (eds.
  • the present invention provides a computer database comprising a computer and software for storing in computer-retrievable form assay data records cross-tabulated, e.g., with data specifying the source of the target-containing sample from which each sequence specificity record was obtained.
  • At least one of the sources of target-containing sample is from a control tissue sample known to be free of pathological disorders.
  • at least one of the sources is a known pathological tissue specimen, e.g., a neoplastic lesion or another tissue specimen to be analyzed for cancer.
  • the assay records cross-tabulate one or more of the following parameters for each target species in a sample: (1) a unique identification code, which can include, e.g., a target molecular structure and/or characteristic separation coordinate (e.g., electrophoretic coordinates); (2) sample source; and (3) absolute and/or relative quantity of the target species present in the sample.
  • the invention also provides for the storage and retrieval of a collection of target data in a computer data storage apparatus, which can include magnetic disks, optical disks, magneto- optical disks, DRAM, SRAM, SGRAM, SDRAM, RDRAM, DDR RAM, magnetic bubble memory devices, and other data storage devices, including CPU registers and on-CPU data storage arrays.
  • the target data records are stored as a bit pattern in an array of magnetic domains on a magnetizable medium or as an array of charge states or transistor gate states, such as an array of cells in a DRAM device (e.g., each cell comprised bf a transistor and a charge storage area, which may be on the transistor).
  • the invention provides such storage devices, and computer systems built therewith, comprising a bit pattern encoding a protein expression finge ⁇ rint record comprising unique identifiers for at least 10 target data records cross-tabulated with target source.
  • the invention preferably provides a method for identifying related peptide or nucleic acid sequences, comprising performing a computerized comparison between a peptide or nucleic acid sequence assay record stored in or retrieved from a computer storage device or database and at least one other sequence.
  • the comparison can include a sequence analysis or comparison algorithm or computer program embodiment thereof (e.g., FASTA, TFASTA, GAP, BESTFIT) and/or the comparison may be of the relative amount of a peptide or nucleic acid sequence in a pool of sequences determined from a polypeptide or nucleic acid sample of a specimen.
  • the invention also preferably provides a magnetic disk, such as an IBM-compatible (DOS, Windows, Windows95/98/2000, Windows NT, OS/2) or other format (e.g., Linux, SunOS, Solaris, AIX, SCO Unix, VMS, MV, Macintosh, etc.) floppy diskette or hard (fixed, Winchester) disk drive, comprising a bit pattern encoding data from an assay of the invention in a file format suitable for retrieval and processing in a computerized sequence analysis, comparison, or relative quantitation method.
  • a magnetic disk such as an IBM-compatible (DOS, Windows, Windows95/98/2000, Windows NT, OS/2) or other format (e.g., Linux, SunOS, Solaris, AIX, SCO Unix, VMS, MV, Macintosh, etc.) floppy diskette or hard (fixed, Winchester) disk drive, comprising a bit pattern encoding data from an assay of the invention in a file format suitable for retrieval and processing
  • the invention also provides a network, comprising a plurality of computing devices linked via a data link, such as an Ethernet cable (coax or lOBaseT), telephone line, ISDN line, wireless network, optical fiber, or other suitable signal transmission medium, whereby at least one network device (e.g., computer, disk array, etc.) comprises a pattern of magnetic domains (e.g., magnetic disk) and/or charge domains (e.g., an array of DRAM cells) composing a " bit pattern encoding data acquired from an assay of the invention.
  • a network device e.g., computer, disk array, etc.
  • a pattern of magnetic domains e.g., magnetic disk
  • charge domains e.g., an array of DRAM cells
  • the invention also provides a method for transmitting assay data that includes generating an electronic signal on an electronic communications device, such as a modem, ISDN terminal adapter, DSL, cable modem, ATM switch, or the like, wherein the signal includes (in native or encrypted format) a bit pattern encoding data from an assay or a database comprising a plurality of assay results obtained by the method of the invention.
  • an electronic communications device such as a modem, ISDN terminal adapter, DSL, cable modem, ATM switch, or the like
  • the signal includes (in native or encrypted format) a bit pattern encoding data from an assay or a database comprising a plurality of assay results obtained by the method of the invention.
  • the invention provides a computer system for comparing a query target to a database containing an array of data structures, such as an assay result obtained by the method of the invention, and ranking database targets based on the degree of identity and gap weight to the target data.
  • a central processor is preferably initialized to load and execute the computer program for alignment and/or comparison of the assay results.
  • Data for a query target is entered into the central processor via an I/O device.
  • Execution of the computer program results in the central processor retrieving the assay data from the data file, which comprises a binary description of an assay result.
  • the target data or record and the computer program can be transferred to secondary memory, which is typically random access memory (e.g., DRAM, SRAM, SGRAM, or SDRAM).
  • Targets are ranked according to the degree of correspondence between a selected assay characteristic (e.g., binding to a selected affinity moiety) and the same characteristic of the query target and results are output via an I/O device.
  • a central processor can be a conventional computer (e.g., Intel Pentium, PowerPC, Alpha, PA-8000, SPARC, MIPS 4400, MIPS 10000, VAX, etc.);
  • a program can be a commercial or public domain molecular biology software package (e.g., UWGCG Sequence Analysis Software, Darwin);
  • a data file can be an optical or magnetic disk, a data server, a memory device (e.g., DRAM, SRAM, SGRAM, SDRAM, EPROM, bubble memory, flash memory, etc.);
  • an I/O device can be a terminal comprising a video display and a keyboard, a modem, an ISDN terminal adapter, an Ethernet port, a punched card reader, a magnetic strip reader, or other suitable I/O device.
  • the invention also preferably provides the use of a computer system, such as that described above, which comprises: (1) a computer; (2) a stored bit pattern encoding a collection of peptide sequence specificity records obtained by the methods of the invention, which may be stored in the computer; (3) a comparison target, such as a query target; and (4) a program for alignment and comparison, typically with rank-ordering of comparison results on the basis of computed similarity values.
  • a computer system such as that described above, which comprises: (1) a computer; (2) a stored bit pattern encoding a collection of peptide sequence specificity records obtained by the methods of the invention, which may be stored in the computer; (3) a comparison target, such as a query target; and (4) a program for alignment and comparison, typically with rank-ordering of comparison results on the basis of computed similarity values.
  • a computer system such as that described above, which comprises: (1) a computer; (2) a stored bit pattern encoding a collection of peptide sequence specificity records obtained by the methods of the invention,
  • Cancer proteins of the present invention may be classified as secreted proteins, transmembrane proteins, or intracellular proteins.
  • the cancer protein is an intracellular protein.
  • Intracellular proteins may be found in the cytoplasm and/or in the nucleus. Intracellular proteins are involved in all aspects of cellular function and replication (including, e.g., signaling pathways); aberrant expression of such proteins often results in unregulated or disregulated cellular processes (see, e.g., Alberts, et al. (eds. 1994) Molecular Biology of the Cell (3d ed.) Garland).
  • intracellular proteins have enzymatic activity such as protein kinase activity, protein phosphatase activity, protease activity, nucleotide cyclase activity, polymerase activity, and the like.
  • Intracellular proteins also serve as docking proteins that are involved in organizing complexes of proteins, or targeting proteins to various subcellular localizations, and are involved in maintaining the structural integrity of organelles.
  • Src-homology-2 (SH2) domains bind tyrosine-phosphorylated targets in a sequence dependent manner.
  • PTB domains which are distinct from SH2 domains, also bind tyrosine phosphorylated targets.
  • SH3 domains bind to proline-rich targets.
  • PH domains, tetratricopeptide repeats and WD domains have been shown to mediate protein-protein interactions.
  • Pfam protein families
  • Pfam protein families
  • the cancer sequences are transmembrane proteins.
  • Transmembrane proteins are molecules that span a phospholipid bilayer of a cell. They may have an intracellular domain, an extracellular domain, or both. The intracellular domains of such proteins may have a number of functions including those already described for intracellular proteins. For example, the intracellular domain may have enzymatic activity and/or may serve as a binding site for additional proteins. Frequently the intracellular domain of transmembrane proteins serves both roles. For example certain receptor tyrosine kinases have both protein kinase activity and SH2 domains. In addition, autophosphorylation of tyrosines on the receptor molecule itself, creates binding sites for additional SH2 domain containing proteins.
  • Transmembrane proteins may contain from one to many transmembrane domains.
  • receptor tyrosine kinases certain cytokine receptors, receptor guanylyl cyclases and receptor serine/threonine protein kinases contain a single transmembrane domain.
  • various other proteins including channels and adenylyl cyclases contain numerous transmembrane domains.
  • Many important cell surface receptors such as G protein coupled receptors (GPCRs) are classified as "seven transmembrane domain" proteins, as they contain 7 membrane spanning regions. Characteristics of transmembrane domains include approximately 17 consecutive hydrophobic amino acids that may be followed by charged amino acids.
  • transmembrane protein receptors include, but are not limited to the insulin receptor, insulin-like growth factor receptor, human growth hormone receptor, glucose transporters, transferrin receptor, epidermal growth factor receptor, low density lipoprotein receptor, epidermal growth factor receptor, leptin receptor, and interleukin receptors, e.g., IL-1 receptor, E -2 receptor, etc.
  • extracellular domains of transmembrane proteins are diverse; however, conserved motifs are found repeatedly among various extracellular domains. conserveed structure and/or functions have been ascribed to different extracellular motifs. Many extracellular domains are involved in binding to other molecules. In one aspect, extracellular domains are found on receptors. Factors that bind the receptor domain include circulating ligands, which may be peptides, proteins, or small molecules such as adenosine and the like. For example, growth factors such as EGF, FGF, and PDGF are circulating growth factors that bind to their cognate receptors to initiate a variety of cellular responses. Other factors include cytokines, mitogenic factors, neurotrophic factors, and the like.
  • Extracellular domains also bind to cell-associated molecules. In this respect, they may mediate cell-cell interactions.
  • Cell-associated ligands can be tethered to the cell, e.g., via a glycosylphosphatidylinositol (GPI) anchor, or may themselves be transmembrane proteins.
  • Extracellular domains may also associate with the extracellular matrix and contribute to the maintenance of the cell structure.
  • Cancer proteins that are transmembrane are particularly preferred in the present invention as they are readily accessible targets for immunotherapeutics, as are described herein.
  • transmembrane proteins can be also useful in imaging modalities. Antibodies may be used to label such readily accessible proteins in situ.
  • antibodies can also label intracellular proteins, in which case samples are typically permeablized to provide access to intracellular proteins.
  • membrane proteins can be processed to release a soluble protein, or to expose a residual fragment. Released soluble proteins may be useful diagnostic markers, processed residual protein fragments may be useful lung markers of disease.
  • transmembrane protein can be made soluble by removing transmembrane sequences, e.g., through recombinant methods.
  • transmembrane proteins that have been made soluble can be made to be secreted through recombinant means by adding an appropriate signal sequence.
  • the cancer proteins are secreted proteins; the secretion of which can be either constitutive or regulated. These proteins may have a signal peptide or signal sequence that targets the molecule to the secretory pathway. Secreted proteins are involved in numerous physiological events; e.g., if circulating, they often serve to transmit signals to various other cell types.
  • the secreted protein may function in an autocrine manner (acting on the cell that secreted the factor), a paracrine manner (acting on cells in close proximity to the cell that secreted the factor), an endocrine manner (acting on cells at a distance, e.g, secretion into the blood stream), or exocrine (secretion, e.g., through a duct or to adjacent epithelial surface as sweat glands, sebaceous glands, pancreatic ducts, lacrimal glands, mammary glands, wax producing glands of the ear, etc.).
  • secreted molecules often find use in modulating or altering numerous aspects of physiology.
  • Cancer proteins that are secreted proteins are particularly preferred in the present invention as they serve as good targets for diagnostic markers, e.g., for blood, plasma, serum, or stool tests. Those which are enzymes may be antibody or small molecule targets. Others may be useful as vaccine targets, e.g., via CTL mechanisms. Use of cancer nucleic acids
  • cancer sequence is initially identified by substantial nucleic acid and/or amino acid sequence homology or linkage to the cancer sequences outlined herein.
  • homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, using either homology programs or hybridization conditions.
  • linked sequences on a mRNA are found on the same molecule.
  • percent identity can be determined using an algorithm such as BLAST.
  • a preferred method utilizes the BLASTN module of WU-BLAST-2 set to the default parameters, with overlap span and overlap fraction set to 1 and 0.125, respectively.
  • Alignment may include the introduction of gaps in the sequences to be aligned.
  • the percentage of homology may be determined based on the number of homologous nucleosides in relation to the total number of nucleosides. Thus, e.g., homology of sequences shorter than those of the sequences identified will be determined using the number of nucleosides in the shorter sequence.
  • the nucleic acid homology is determined through hybridization studies.
  • nucleic acids which hybridize under high stringency to a described nucleic acid, or its complement, or is also found on naturally occurring mRNAs is considered a cancer sequence.
  • less stringent hybridization conditions are used; e.g., moderate or low stringency conditions may be used; see Ausubel, supra, and Tijssen, supra.
  • the cancer nucleic acid sequences of the invention e.g., the sequences in Tables 1-80, can be fragments of larger genes, e.g., they are nucleic acid segments. "Genes" in this context includes coding regions, non-coding regions, and mixtures of coding and non-coding regions.
  • extended sequences, in either direction, of the cancer genes can be obtained, using techniques well known for cloning either longer sequences or the full length sequences; see Ausubel, et al., supra. Much can be done by informatics and many sequences can be clustered to include multiple sequences corresponding to a single gene, e.g., systems such as UniGene (see, http://www.ncbi.nlm.nih.gov/UniGene/).
  • a cancer nucleic acid Once a cancer nucleic acid is identified, it can be cloned and, if necessary, its constituent parts recombined to form the entire cancer nucleic acid coding regions or the entire mRNA sequence.
  • the recombinant cancer nucleic acid Once isolated from its natural source, e.g., contained within a plasmid or other vector or excised therefrom as a linear nucleic acid segment, the recombinant cancer nucleic acid can be further used as a probe to identify and isolate other cancer nucleic acids, e.g., extended coding regions. It can also be used as a "precursor" nucleic acid to make modified or variant cancer nucleic acids and proteins.
  • nucleic acid probes to the cancer nucleic acids are made and attached to biochips to be used in screening and diagnostic methods, as outlined below, or for administration, e.g., for gene therapy, vaccine, RNAi, and/or antisense applications.
  • cancer nucleic acids that include coding regions of cancer proteins can be put into expression vectors for the expression of cancer proteins, again for screening pu ⁇ oses or for administration to a patient.
  • nucleic acid probes to cancer nucleic acids are made.
  • the nucleic acid probes attached to the biochip are designed to be substantially complementary to the cancer nucleic acids, e.g., the target sequence (either the target sequence of the sample or to other probe sequences, e.g., in sandwich assays), such that hybridization of the target sequence and the probes of the present invention occurs.
  • this complementarity need not be perfect; there may be any number of base pair mismatches which will interfere with hybridization between the target sequence and the single stranded nucleic acids of the present invention.
  • the sequence is not a complementary target sequence.
  • substantially complementary herein is meant that the probes are sufficiently complementary to the target sequences to hybridize under normal reaction conditions, particularly high stringency conditions, as outlined herein.
  • a nucleic acid probe is generally single stranded but can be partially single and partially double stranded.
  • the strandedness of the probe is dictated by the structure, composition, and properties of the target sequence.
  • the nucleic acid probes range from about 8-100 bases long, with from about 10-80 bases being prefened, and from about 30-50 bases being particularly preferred. That is, generally whole genes are not used. In some embodiments, much longer nucleic acids can be used, up to hundreds of bases.
  • more than one probe per sequence is used, with either overlapping probes or probes to different sections of the target being used. That is, two, three, four or more probes, with three being preferred, are used to build in a redundancy for a particular target.
  • the probes can be overlapping (e.g., have some sequence in common), or separate.
  • PCR primers may be used to amplify signal for higher sensitivity.
  • Nucleic acids can be attached or immobilized to a solid support in a wide variety of ways. By “immobilized” and grammatical equivalents herein is meant the association or binding between the nucleic acid probe and the solid support is sufficient to be stable under the conditions of binding, washing, analysis, and removal as outlined.
  • the binding can typically be covalent or non-covalent.
  • non-covalent binding and grammatical equivalents herein is meant one or more of electrostatic, hydrophilic, and hydrophobic interactions. Included in non- covalent binding is the covalent attachment of a molecule, e.g., streptavidin to the support and the non-covalent binding of the biotinylated probe to the streptavidin.
  • covalent binding and grammatical equivalents herein is meant that the two moieties, the solid support and the probe, are attached by at least one bond, including sigma bonds, pi bonds, and coordination bonds.
  • Covalent bonds can be formed directly between the probe and the solid support or can be formed by a cross linker or by inclusion of a specific reactive group on either the solid support or the probe or both molecules. Immobilization may also involve a combination of covalent and non-covalent interactions.
  • the probes are attached to the biochip in a wide variety of ways.
  • the nucleic acids can either be synthesized first, with subsequent attachment to the biochip, or can be directly synthesized on the biochip.
  • the biochip comprises a suitable solid substrate.
  • substrate or “solid support” or other grammatical equivalents herein is meant a material that can be modified for the attachment or association of the nucleic acid probes and is amenable to at least one detection method. Often, the substrate may contain discrete individual sites appropriate for individual partitioning and identification.
  • the number of possible substrates is very large, and include, but are not limited to, glass and modified or functionalized glass, plastics (including acrylics, polystyrene and copolymers of styrene and other materials, polypropylene, polyethylene, polybutylene, polyurethanes, TeflonJ, etc.), polysaccharides, nylon or nitrocellulose, resins, silica or silica-based materials including silicon and modified silicon, carbon, metals, inorganic glasses, plastics, etc.
  • the substrates allow optical detection and do not appreciably fluoresce. See WO 0055627.
  • the substrate is planar, although other configurations of substrates may be used as well.
  • the probes may be placed on the inside surface of a tube for flow- through sample analysis to minimize sample volume.
  • the substrate may be flexible, such as a flexible foam, including closed cell foams made of particular plastics.
  • the surface of the biochip and the probe may be derivatized with chemical functional groups for subsequent attachment of the two.
  • the biochip is derivatized with a chemical functional group including, but not limited to, amino groups, carboxy groups, oxo groups, and thiol groups, with amino groups being particularly preferred.
  • the probes can be attached using functional groups on the probes.
  • nucleic acids containing amino groups can be attached to surfaces comprising amino groups, e.g., using linkers; e.g., homo-or hetero-bifunctional linkers as are well known (see 1994 Pierce Chemical Company catalog, technical section on cross-linkers, pages 155-
  • additional linkers such as alkyl groups (including substituted and heteroalkyl groups) may be used.
  • oligonucleotides are synthesized, and then attached to the surface of the solid support. Either the 5' or 3' terminus may be attached to the solid support, or attachment may be via linkage to an internal nucleoside.
  • the immobilization to the solid support may be very strong, yet non-covalent.
  • biotinylated oligonucleotides can be made, which bind to surfaces covalently coated with streptavidin, resulting in attachment.
  • the oligonucleotides may be synthesized on the surface.
  • photoactivation techniques utilizing photopolymerization compounds and techniques are used.
  • the nucleic acids can be synthesized in situ, using known photolithographic techniques, such as those described in WO 95/25116; WO 95/35505; U.S. Patent Nos. 5,700,637 and 5,445,934; and references cited within, all of which are expressly inco ⁇ orated by reference; these methods of attachment form the basis of the Affymetrix GeneChipTM technology.
  • amplification-based assays are performed to measure the expression level of cancer-associated sequences. These assays are typically performed in conjunction with reverse transcription.
  • a cancer-associated nucleic acid sequence acts as a template in an amplification reaction (e.g., Polymerase Chain Reaction, or PCR).
  • an amplification reaction e.g., Polymerase Chain Reaction, or PCR.
  • the amount of amplification product will be proportional to the amount of template in the original sample. Comparison to appropriate controls provides a measure of the amount of cancer-associated RNA.
  • Methods of quantitative amplification are well known. Detailed protocols for quantitative PCR are provided, e.g., in Innis, et al. (1990) PCR Protocols: A Guide to Methods and Applications Academic Press.
  • a TaqMan based assay is used to measure expression.
  • TaqMan based assays use a fluorogenic oligonucleotide probe that contains a 5' fluorescent dye and a 3' quenching agent. The probe hybridizes to a PCR product, but cannot itself be extended due to a blocking agent at the 3' end.
  • the 5' nuclease activity of the polymerase e.g., AmpliTaq
  • This cleavage separates the 5' fluorescent dye and the 3' quenching agent, thereby resulting in an increase in fluorescence as a function of amplification (see, e.g., literature provided by Perkin-Elmer, e.g., www2.perkin-elmer.com).
  • ligase chain reaction (LCR) (see Wu and Wallace (1989) Genomics 4:560-569, Landegren, et al. (1988) Science 241:1077-1080, and Barringer, et al. (1990) Gene 89:117-122), transcription amplification (Kwoh, et al. (1989) Proc. Natl. Acad. Sci. USA 86:1173-1177), self-sustained sequence replication (Guatelli, et al. (1990) Proc. Natl. Acad. Sci. USA 87:1874- 1878), dot PCR, linker adapter PCR, etc. Expression of cancer proteins from nucleic acids
  • cancer nucleic acids e.g., encoding cancer proteins
  • expression vectors are well known (see, e.g., Ausubel, supra, and Fernandez and Hoeffier (eds. 1999) Gene Expression Systems Academic Press) to express proteins.
  • the expression vectors may be either self replicating extrachromosomal vectors or vectors which integrate into a host genome.
  • these expression vectors include transcriptional and translational regulatory nucleic acid operably linked to the nucleic acid encoding the cancer protein.
  • control sequences refers to DNA sequences used for the expression of an operably linked coding sequence in a particular host organism. Control sequences that are suitable for prokaryotes, e.g., include a promoter, optionally an operator sequence, and a ribosome binding site. Eukaryotic cells are known to utilize promoters, polyadenylation signals, and enhancers. Nucleic acid is "operably linked” when it is placed into a functional relationship with another nucleic acid sequence.
  • DNA for a presequence or secretory leader is operably linked to DNA for a polypeptide if it is expressed as a preprotein that participates in the secretion of the polypeptide; a promoter or enhancer is operably linked to a coding sequence if it affects the transcription of the sequence; or a ribosome binding site is operably linked to a coding sequence if it is positioned so as to facilitate translation.
  • "operably linked" means that the DNA sequences being linked are contiguous, and, in the case of a secretory leader, contiguous and in reading phase. However, enhancers do not have to be contiguous. Linking is typically accomplished by ligation at convenient restriction sites.
  • Transcriptional and translational regulatory nucleic acid will generally be appropriate to the host cell used to express the cancer protein. Numerous types of appropriate expression vectors and suitable regulatory sequences are known for a variety of host cells.
  • transcriptional and translational regulatory sequences may include, but are not limited to, promoter sequences, ribosomal binding sites, transcriptional start and stop sequences, translational start and stop sequences, and enhancer or activator sequences.
  • the regulatory sequences include a promoter and transcriptional start and stop sequences.
  • Promoter sequences may be either constitutive or inducible promoters.
  • the promoters may be either naturally occurring promoters or hybrid promoters. Hybrid promoters, which combine elements of more than one promoter, are also known, and are useful in the present invention.
  • An expression vector may comprise additional elements.
  • the expression vector may have two replication systems, thus allowing it to be maintained in two organisms, e.g., in mammalian or insect cells for expression and in a prokaryotic host for cloning arid amplification.
  • the expression vector often contains at least one sequence homologous to the host cell genome, and preferably two homologous sequences which flank the expression construct.
  • the integrating vector may be directed to a specific locus in the host cell by selecting the appropriate homologous sequence for inclusion in the vector. Constructs for integrating vectors are available. See, e.g., Fernandez and Hoeffler, supra; and Kitamura, et al. (1995) Proc. Nat'l Acad. Sci. USA 92:9146- 9150.
  • the expression vector contains a selectable marker gene to allow the selection of transformed host cells. Selection genes are well known and will vary with the host cell used.
  • the cancer proteins of the present invention are usually produced by culturing a host cell transformed with an expression vector containing nucleic acid encoding a cancer protein, under the appropriate conditions to induce or cause expression of the cancer protein.
  • Conditions appropriate for cancer protein expression will vary with the choice of the expression vector and the host cell, and will be easily ascertained through routine experimentation or optimization.
  • the use of constitutive promoters in the expression vector will require optimizing the growth and proliferation of the host cell, while the use of an inducible promoter requires the appropriate growth conditions for induction.
  • the timing of the harvest is important.
  • the baculoviral systems used in insect cell expression are lytic viruses, and thus harvest time selection can be crucial for product yield.
  • Appropriate host cells include yeast, bacteria, archaebacteria, fungi, and insect and animal cells, including mammalian cells. Of particular interest are Saccharomyces cerevisiae and other yeasts, E. coli, Bacillus subtilis, Sf9 cells, C129 cells, 293 cells, Neurospora, BHK, CHO, COS, HeLa cells, HUVEC (human umbilical vein endothelial cells), THP1 cells (a macrophage cell line), and various other human cells and cell lines.
  • the cancer proteins are expressed in mammalian cells.
  • Mammalian expression systems may be used, and include retroviral and adenoviral systems.
  • One expression vector system is a retroviral vector system such as is generally described in PCT/US97/01019 and PCT/US97/01048.
  • mammalian promoters are the promoters from mammalian viral genes, since the viral genes are often highly expressed and have a broad host range. Examples include the SV40 early promoter, mouse mammary tumor virus LTR promoter, adenovirus major late promoter, he ⁇ es simplex virus promoter, and the CMV promoter (see, e.g., Fernandez and Hoeffler, supra).
  • transcription termination and polyadenylation sequences recognized by mammalian cells are regulatory regions located 3' to the translation stop codon and thus, together with the promoter elements, flank the coding sequence.
  • transcription terminator and polyadenlyation signals include those derived from SV40.
  • Methods of introducing exogenous nucleic acid into mammalian hosts, as well as other hosts, are available, and will vary with the host cell used. Techniques include dextran-mediated transfection, calcium phosphate precipitation, polybrene mediated transfection, protoplast fusion, electroporation, viral infection, encapsulation of the polynucleotide(s) in liposomes, and direct microinjection of the DNA into nuclei.
  • cancer proteins are expressed in bacterial systems. Promoters from bacteriophage may also be used.
  • synthetic promoters and hybrid promoters are also useful; e.g., the tac promoter is a hybrid of the frp and lac promoter sequences.
  • a bacterial promoter can include naturally occurring promoters of non- bacterial origin that have the ability to bind bacterial RNA polymerase and initiate transcription. In addition to a functioning promoter sequence, an efficient ribosome binding site is desirable.
  • the expression vector may also include a signal peptide sequence that provides for secretion of the cancer protein in bacteria. The protein is either secreted into the growth media (gram- positive bacteria) or into the periplasmic space, located between the inner and outer membrane of the cell (gram-negative bacteria).
  • the bacterial expression vector may also include a selectable marker gene to allow for the selection of bacterial strains that have been transformed.
  • Suitable selection genes include genes which render the bacteria resistant to drugs such as ampicillin, chloramphenicol, erythromycin, kanamycin, neomycin, and tetracycline. Selectable markers also include biosynthetic genes, such as those in the histidine, tryptophan, and leucine biosynthetic pathways. These components are assembled into expression vectors.
  • Expression vectors for bacteria are well known, and include vectors for Bacillus subtilis, E. coli, Streptococcus cremoris, and Streptococcus lividans, among others (e.g., Fernandez and Hoeffler, supra).
  • the bacterial expression vectors are transformed into bacterial host cells using techniques such as calcium chloride treatment, electroporation, and others.
  • cancer proteins are produced in insect cells using, e.g., expression vectors for the transformation of insect cells, and in particular, baculovirus-based expression vectors.
  • a cancer protein is produced in yeast cells.
  • yeast expression systems are well known, and include expression vectors for Saccharomyces cerevisiae, Candida albicans and C. maltosa, Hansenula polymo ⁇ ha, Kluyveromyces fragilis and K. lactis, Pichia guillerimondii and P. pastoris, Schizosaccharomyces pombe, and Yarrowia lipolytica.
  • the cancer protein may also be made as a fusion protein, using available techniques.
  • the cancer protein may be fused to a carrier protein to form an immunogen.
  • the cancer protein may be made as a fusion protein to increase expression, or for other reasons.
  • the cancer protein is a cancer peptide
  • the nucleic acid encoding the peptide may be linked to other nucleic acid for expression pu ⁇ oses. Fusion with detection epitope tags can be made, e.g., with FLAG, His6, myc, HA, etc.
  • the cancer protein is purified or isolated after expression.
  • Cancer proteins may be isolated or purified in a variety of ways depending on what other components are present in the sample and the requirements for purified product, e.g., natural conformation or denatured.
  • Standard purification methods include ammonium sulfate precipitations, electrophoretic, molecular, immunological, and chromatographic techniques, including ion exchange, hydrophobic, affinity, and reverse-phase HPLC chromatography, and chromatofocusing.
  • the cancer protein may be purified using a standard anti- cancer protein antibody column. Ultrafilfration and diafilfration techniques, in conjunction with protein concentration, are also useful.
  • cancer proteins and nucleic acids are useful in a number of applications. They may be used as immunoselection reagents, as vaccine reagents, as screening agents, therapeutic entities, for production of antibodies, as transcription or translation inhibitors, etc. Variants of cancer proteins
  • cancer proteins are amino acid variants " of the naturally occurring sequences, as determined herein.
  • the variants are preferably greater than about 75% homologous to the wild-type sequence, more preferably greater than about 80%, even more preferably greater than about 85%, and most preferably greater than 90%.
  • the homology will be as high as about 93-95% or 98%.
  • nucleic acids homology in this context means sequence similarity or identity, with identity being preferred. This homology will be determined using standard techniques, as are outlined above for nucleic acid homologies.
  • Cancer proteins of the present invention may be shorter or longer than the wild type amino acid sequences.
  • included within the definition of cancer proteins are portions or fragments of the wild type sequences herein.
  • the cancer nucleic acids of the invention may be used to obtain additional coding regions, and thus additional protein sequence.
  • the cancer proteins are derivative or variant cancer proteins as compared to the wild-type sequence. That is, as outlined more fully below, the derivative cancer peptide will often contain at least one amino acid substitution, deletion, or insertion, with amino acid substitutions being particularly preferred. The amino acid substitution, insertion, or deletion may occur at many residue positions within the cancer peptide.
  • amino acid sequence variants typically fall into one or more of three classes: substitutional, insertional, or deletional variants. These variants ordinarily are prepared by site specific mutagenesis of nucleotides in the DNA encoding the cancer protein, using cassette or PCR mutagenesis or other techniques, to produce DNA encoding the variant, and thereafter expressing the DNA in recombinant cell culture as outlined above. However, variant cancer protein fragments having up to about 100-150 residues may be prepared by in vitro synthesis using established techniques. Amino acid sequence variants are characterized by the predetermined nature of the variation, a feature that sets them apart from naturally occurring allelic or interspecies variation of the cancer protein amino acid sequence.
  • the variants typically exhibit a similar qualitative biological activity as a naturally occurring analogue, although variants can also be selected which have modified characteristics. While the site or region for introducing an amino acid sequence variation is often predetermined, the mutation per se need not be predetermined. For example, in order to optimize the performance of a mutation at a given site, random mutagenesis may be conducted at the target codon or region and the expressed cancer variants screened for the optimal combination of desired activity. Techniques for making substitution mutations at predetermined sites in DNA having a known sequence are well known, e.g., M13 primer mutagenesis and PCR mutagenesis. Screening of mutants is often done using assays of cancer protein activities.
  • Amino acid substitutions are typically of single residues; insertions usually will be on the order of from about 1-20 amino acids, although considerably larger insertions maybe tolerated. Deletions generally range from about 1-20 residues, although in some cases deletions may be much larger.
  • substitutions deletions, insertions, or combination thereof may be used to arrive at a final derivative. Generally these changes are done on a few amino acids to minimize the alteration of the molecule. However, larger changes may be tolerated in certain circumstances. When small alterations in the characteristics of the cancer protein are desired, substitutions are generally made in accordance with the amino acid substitution relationships described.
  • variants typically exhibit essentially the same qualitative biological activity and will elicit the same immune response as a naturally-occurring analog, although variants also are selected to modify the characteristics of cancer proteins as needed.
  • the variant may be designed such that a biological activity of the cancer protein is altered. For example, glycosylation sites may be added, altered, or removed.
  • substitutions that are less conservative than those described above.
  • substitutions may be made which more significantly affect: the structure of the polypeptide backbone in the area of the alteration, for example the alpha-helical or beta-sheet structure; the charge or hydrophobicity of the molecule at the target site; or the bulk of the side chain.
  • substitutions which generally are expected to produce the greatest changes in the polypeptide's properties are those in which (a) a hydrophilic residue, e.g., serine or threone is substituted for (or by) a hydrophobic residue, e.g., leucine, isoleucine, phenylalanine, valine, or alanine; (b) a cysteine or proline is substituted for (or by) another residue; (c) a residue having an electropositive side chain, e.g., lysine, arginine, or histidine, is substituted for (or by) an electronegative residue, e.g., glutamic or aspartic acid; (d) a residue having a bulky side chain, e.g., phenylalanine, is substituted for (or by) one not having a side chain, e.g., glycine; or (e) a proline residue is inco ⁇ orated or substituted, which changes the degree
  • Variants typically exhibit a similar qualitative biological activity and will elicit the same immune response as the naturally-occurring analog, although variants also are selected to modify the characteristics of the skin cancer proteins as needed.
  • the variant may be designed such that the biological activity of the cancer protein is altered. For example, glycosylation sites may be altered or removed.
  • Covalent modifications of cancer polypeptides are included within the scope of this invention.
  • One type of covalent modification includes reacting targeted amino acid residues of a cancer polypeptide with an organic derivatizing agent that is capable of reacting with selected side chains or the N-or C-terminal residues of a cancer polypeptide.
  • Derivatization with bifunctional agents is useful, for instance, for crosslinking cancer polypeptides to a water- insoluble support matrix or surface for use in a method for purifying anti-cancer polypeptide antibodies or screening assays, as is more fully described below.
  • crosslinking agents include, e.g., l,l-bis(diazoacetyl)-2-phenylethane, glutaraldehyde, N- hydroxysuccinimide esters, e.g., esters with 4-azidosalicylic acid, homobifunctional imidoesters, including disuccinimidyl esters such as 3,3'-dithiobis(succinimidylpropionate), bifunctional maleimides such as bis-N-maleimido-l,8-octane and agents such as methyl-3-((p- azidophenyl)dithio)propioimidate.
  • l,l-bis(diazoacetyl)-2-phenylethane glutaraldehyde
  • N- hydroxysuccinimide esters e.g., esters with 4-azidosalicylic acid
  • homobifunctional imidoesters including disuccinimidyl esters such
  • Another type of covalent modification of the cancer polypeptide included within the scope of this invention comprises altering the native glycosylation pattern of the polypeptide.
  • "Altering the native glycosylation pattern” is intended for pu ⁇ oses herein to mean deleting one or more carbohydrate moieties found in native sequence cancer polypeptide, and/or adding one or more glycosylation sites that are not present in the native sequence cancer polypeptide.
  • Glycosylation patterns can be altered in many ways. Different cell types to express cancer- associated sequences can result in different glycosylation patterns.
  • Addition of glycosylation sites to cancer polypeptides may also be accomplished by altering the amino acid sequence thereof.
  • the alteration may be made, e.g., by the addition of, or substitution by, one or more serine or threonine residues to the native sequence cancer polypeptide (for O-linked glycosylation sites).
  • the cancer amino acid sequence may optionally be altered through changes at the DNA level, particularly by mutating the DNA encoding the cancer polypeptide at preselected bases such that codons are generated that will translate into the desired amino acids.
  • Another means of increasing the number of carbohydrate moieties on the cancer polypeptide is by chemical or enzymatic coupling of glycosides to the polypeptide. See, e.g., WO 87/05330; pp. 259-306 in Aplin and Wriston (1981) CRC Crit. Rev. Biochem. Removal of carbohydrate moieties present on the cancer polypeptide may be accomplished chemically or enzymatically or by mutational substitution of codons encoding for amino acid residues that serve as targets for glycosylation. Chemical deglycosylation techniques are applicable. See, e.g., Sojar and Bahl (1987) Arch. Biochem. Biophys. 259:52-57 and Edge, et al. (1981) Anal.
  • Enzymatic cleavage of carbohydrate moieties on polypeptides can be achieved by the use of a variety of endo-and exo-glycosidases. See, e.g., Thotakura, et al. (1987) Meth. Enzymol. 138:350-359.
  • Another type of covalent modification of cancer comprises linking the cancer polypeptide to one of a variety of nonproteinaceous polymers, e.g., polyethylene glycol, polypropylene glycol, or polyoxyalkylenes, in the manner set forth in U.S. Patent Nos. 4,640,835; 4,496,689; 4,301,144; 4,670,417; 4,791,192, or 4,179,337.
  • Cancer polypeptides of the present invention may also be modified in a way to form chimeric molecules comprising a cancer polypeptide fused to another heterologous polypeptide or amino acid sequence.
  • such a chimeric molecule comprises a fusion of a cancer polypeptide with a tag polypeptide which provides an epitope to which an anti-tag antibody can selectively bind.
  • the epitope tag is generally placed at the amino-or carboxyl- terminus of the cancer polypeptide. The presence of such epitope-tagged forms of a cancer polypeptide can be detected using an antibody against the tag polypeptide. Also, provision of the epitope tag enables the cancer polypeptide to be readily purified by affinity purification using an anti-tag antibody or another type of affinity matrix that binds to the epitope tag.
  • the chimeric molecule may comprise a fusion of a cancer polypeptide with an immunoglobulin or a particular region of an immunoglobulin.
  • a fusion could be to the Fc region of an IgG molecule.
  • tag polypeptides and their respective antibodies are available.
  • Examples "' include poly-histidine (poly-his) or poly-histidine-glycine (poly-his-gly) tags; HIS6 and metal chelation tags, the flu HA tag polypeptide and its antibody 12CA5 (Field, et al. (1988) Mol. Cell. Biol. 8:2159-2165); the c-myc tag and the 8F9, 3C7, 6E10, G4, B7, and 9E10 antibodies thereto (Evan, et al. (1985) Molecular and Cellular Biology 5:3610-3616); and the He ⁇ es Simplex virus glycoprotein D (gD) tag and its antibody (Paborsky, et al.
  • gD He ⁇ es Simplex virus glycoprotein D
  • tag polypeptides include the Flag-peptide (Hopp, et al. (1988) BioTechnology 6:1204-1210); the KT3 epitope peptide (Martin, et al. (1992) Science 255:192-194); tubulin epitope peptide (Skinner, et al. (1991) J. Biol. Chem. 266:15163-15166); and the T7 gene 10 protein peptide tag (Lutz-Freyermuth, et al. (1990) Proc. Natl. Acad. Sci. USA 87:6393-6397).
  • probe or degenerate polymerase chain reaction (PCR) primer sequences may be used to find other related cancer proteins from humans or other organisms.
  • Particularly useful probe and/or PCR primer sequences include the unique areas of the cancer nucleic acid sequence.
  • Preferred PCR primers are from about 15-35 nucleotides in length, with from about 20-30 being preferred, and may contain inosine as needed. The conditions for PCR reaction have been well described (e.g., Innis, PCR Protocols, supra).
  • cancer proteins can be made that are longer than those encoded by the nucleic acids of the Tables, e.g., by the elucidation of extended sequences, the addition of epitope or purification tags, the addition of other fusion sequences, etc.
  • Cancer proteins may also be identified as being encoded by cancer nucleic acids. Thus, cancer proteins are encoded by nucleic acids that will hybridize to the sequences of the sequence listings, or their complements, as outlined herein. Antibodies to cancer proteins
  • the cancer protein when the cancer protein is to be used to generate antibodies, e.g., for immunotherapy or immunodiagnosis, the cancer protein should share at least one epitope or determinant with the full length protein.
  • epitope or “determinant” herein is typically meant a portion of a protein which will generate and/or bind an antibody or T-cell receptor in the context of MHC.
  • the epitope is unique; that is, antibodies generated to a unique epitope show little or no cross-reactivity.
  • the epitope is selected from a protein sequence set out in the tables. Methods of preparing polyclonal antibodies exist (e.g., Coligan, supra; and Harlow and
  • Polyclonal antibodies can be raised in a mammal, e.g., by one or more injections of an immunizing agent and, if desired, an adjuvant.
  • the immunizing agent and/or adjuvant will be injected in the mammal by multiple subcutaneous or intraperitoneal injections.
  • the immunizing agent may include a protein encoded by a nucleic acid of Tables 2A-80 or fragment thereof or a fusion protein thereof. It may be useful to conjugate the immunizing agent to a protein known to be immunogenic in the mammal being immunized.
  • immunogenic proteins include but are not limited to keyhole limpet hemocyanin, serum albumin, bovine thyroglobulin, and soybean trypsin inhibitor.
  • adjuvants which may be employed include Freund's complete adjuvant and MPL-TDM adjuvant (monophosphoryl Lipid A, synthetic trehalose dicorynomycolate).
  • MPL-TDM adjuvant monophosphoryl Lipid A, synthetic trehalose dicorynomycolate.
  • the antibodies may, alternatively, be monoclonal antibodies. Monoclonal antibodies may be prepared using hybridoma methods, such as those described by Kohler and Milstein (1975) Nature 256:495.
  • a mouse, hamster, or other appropriate host animal is typically immunized with an immunizing agent to elicit lymphocytes that produce or are capable of producing antibodies that will specifically bind to the immunizing agent.
  • the lymphocytes may be immunized in vitro.
  • the immunizing agent will typically include a polypeptide encoded by a nucleic acid of the tables or fragment thereof, or a fusion protein thereof.
  • PBLs peripheral blood lymphocytes
  • spleen cells or lymph node cells are used if non-human mammalian sources are desired.
  • the lymphocytes are then fused with an immortalized cell line using a suitable fusing agent, such as polyethylene glycol, to form a hybridoma cell (e.g., pp. 59-103 in Goding (1986) Monoclonal Antibodies: Principles and Practice Academic Press).
  • Immortalized cell lines are usually transformed mammalian cells, particularly myeloma cells of rodent, bovine, or human origin. Usually, rat or mouse myeloma cell lines are employed.
  • the hybridoma cells may be cultured in a suitable culture medium that preferably contains one or more substances that inhibit the growth or survival of the unfused, immortalized cells.
  • the culture medium for the hybridomas typically will include hypoxanthine, aminopterin, and thymidine ("HAT medium"), which substances prevent the growth of HGPRT-deficient cells.
  • HGPRT medium hypoxanthine, aminopterin, and thymidine
  • the antibodies are bispecific antibodies. Bispecific antibodies are monoclonal, preferably human or humanized, antibodies that have binding specificities for at least two different antigens or that have binding specificities for two epitopes on the same antigen.
  • one of the binding specificities is for a protein encoded by a nucleic acid of the tables or a fragment thereof, the other one is for another antigen, and preferably for a cell-surface protein or receptor or receptor subunit, preferably one that is tumor specific.
  • the antibodies to cancer protein are capable of reducing or eliminating a biological function of a cancer protein, in a naked form or conjugated to an effector moiety, as is described below. That is, the addition of anti-cancer protein antibodies (either polyclonal or preferably monoclonal) to cancer tissue (or cells containing cancer) may reduce or eliminate the cancer.
  • at least a 25% decrease in activity, growth, size, or the like is preferred, with at least about 50% being particularly prefened and about a 95-100% decrease being especially prefened.
  • the antibodies to the cancer proteins are humanized antibodies (e.g., Xenerex Biosciences, Medarex, Inc., Abgenix, Inc., Protein Design Labs, Inc.)
  • Humanized forms of non-human (e.g., murine) antibodies are chimeric molecules of immunoglobulins, immunoglobulin chains or fragments thereof (such as Fv, Fab, Fab', F(ab')2 or other antigen-binding subsequences of antibodies) wliich contain minimal sequence derived from non-human immunoglobulin.
  • Humanized antibodies include human immunoglobulins (recipient antibody) in which residues from a complementary determining region (CDR) of the recipient are replaced by residues from a CDR of a non-human species (donor antibody) such as mouse, rat, or rabbit having the desired specificity, affinity, and capacity.
  • CDR complementary determining region
  • donor antibody such as mouse, rat, or rabbit having the desired specificity, affinity, and capacity.
  • Fv framework residues of a human immunoglobulin are replaced by conesponding non-human residues.
  • Humanized antibodies may also comprise residues which are found neither in the recipient antibody nor in the imported CDR or framework sequences.
  • a humanized antibody will comprise substantially all of at least one, and typically two, variable domains, in which all or substantially all of the CDR regions conespond to those of a non-human immunoglobulin and all or substantially all of the framework (FR) regions are those of a human immunoglobulin consensus sequence.
  • the humanized antibody optimally also will typically comprise at least a portion of an immunoglobulin constant region (Fc), typically that of a human immunoglobulin (Jones, et al. (1986) Nature 321 :522-525; Riechmann, et al. (1988) Nature 332:323-329; and Presta (1992) Cun. Op. Struct. Biol. 2:593-596).
  • Humanization can be essentially performed following the method of Winter and co-workers (Jones, et al. (1986) Nature 321:522-525; Riechmann, et al. (1988) Nature 332:323-327; Verhoeyen, et al. (1988) Science 239:1534-1536), by substituting rodent CDRs or CDR sequences for conesponding sequences of a human antibody.
  • rodent CDRs or CDR sequences for conesponding sequences of a human antibody.
  • such humanized antibodies are chimeric antibodies (U.S. Patent No. 4,816,567), wherein substantially less than an intact human variable domain has been substituted by conesponding sequence from a non-human species.
  • Human antibodies can also be produced using phage display libraries (Hoogenboom and Winter (1992) J. Mol.
  • human antibodies can be made by introducing human immunoglobulin loci into transgenic animals, e.g., mice in which the endogenous immunoglobulin genes have been partially or completely inactivated.
  • immunotherapy is meant treatment of cancer with an antibody raised against cancer proteins.
  • immunotherapy can be passive or active.
  • Passive immunotherapy as defined herein is the passive transfer of antibody to a recipient (patient).
  • Active immunization is the induction of antibody and/or T-cell responses in a recipient (patient).
  • Induction of an immune response is the result of providing the recipient with an antigen to which antibodies are raised.
  • the antigen may be provided by injecting a polypeptide against which antibodies are desired to be raised into a recipient, or contacting the recipient with a nucleic acid capable of expressing the antigen and under conditions for expression of the antigen, leading to an immune response.
  • the cancer proteins against which antibodies are raised are secreted proteins as described above.
  • antibodies used for treatment may bind and prevent the secreted protein from binding to its receptor, thereby inactivating the secreted cancer protein, e.g., in autocrine signaling.
  • the cancer protein to which antibodies are raised is a transmembrane protein.
  • antibodies used for treatment may bind the extracellular domain of the cancer protein and prevent it from binding to other proteins, such as circulating ligands or cell-associated molecules.
  • the antibody may cause down- regulation of the transmembrane cancer protein.
  • the antibody may be a competitive, non- competitive or uncompetitive inhibitor of protein binding to the extracellular domain of the cancer protein.
  • the antibody may also be an antagonist of the cancer protein.
  • the antibody may prevent activation of the transmembrane cancer protein, or may induce or suppress a particular cellular pathway. In one aspect, when the antibody prevents the binding of other molecules to the cancer protein, the antibody prevents growth of the cell.
  • the antibody may also be used to target or sensitize the cell to cytotoxic agents, including, but not limited to TNF- ⁇ , TNF- ⁇ , IL-1, ESTF- ⁇ , and IL-2, or chemotherapeutic agents including 5FU, vinblastine, actinomycin D, cisplatin, methotrexate, and the like.
  • cytotoxic agents including, but not limited to TNF- ⁇ , TNF- ⁇ , IL-1, ESTF- ⁇ , and IL-2, or chemotherapeutic agents including 5FU, vinblastine, actinomycin D, cisplatin, methotrexate, and the like.
  • the antibody may belong to a sub-type that activates serum complement when complexed with the transmembrane protein thereby mediating cytotoxicity or antigen-dependent cytotoxicity (ADCC).
  • ADCC antigen-dependent cytotoxicity
  • cancer may be treated by administering to a patient antibodies directed against the transmembrane cancer protein.
  • Antibody-labeling
  • the antibody is conjugated to an effector moiety.
  • the effector moiety can be various molecules, including labeling moieties such as radioactive labels or fluorescent labels, or can be a therapeutic moiety.
  • the therapeutic moiety is a small molecule that modulates the activity of a cancer protein.
  • the therapeutic moiety may modulate the activity of molecules associated with or in close proximity to a cancer protein.
  • the therapeutic moiety may inhibit enzymatic or signaling activity such as protease or collagenase or protein kinase activity associated with cancer, or be an attractant of other cells, such as NK cells. See, e.g., USSN 09/544,494.
  • the therapeutic moiety can also be a cytotoxic agent.
  • targeting the cytotoxic agent to cancer tissue or cells results in a reduction in the number of afflicted cells, thereby reducing symptoms associated with cancer.
  • Cytotoxic agents are numerous and varied and include, but are not limited to, cytotoxic drugs or toxins or active fragments of such toxins. Suitable toxins and their conesponding fragments include diphtheria A chain, exotoxin A chain, ricin A chain, abrin A chain, curcin, crotin, phenomycin, enomycin, saporin, auristatin, and the like.
  • Cytotoxic agents also include radiochemicals made by conjugating radioisotopes to antibodies raised against cancer proteins, or binding of a radionuclide to a chelating agent that has been covalently attached to the antibody.
  • Targeting the therapeutic moiety to transmembrane cancer proteins not only serves to increase the local concentration of therapeutic moiety in the cancer afflicted area, but also serves to reduce deleterious side effects that may be associated with the untargeted therapeutic moiety.
  • Antibody fragments may be used to target toxin loaded liposomes.
  • the cancer protein against which the antibodies are raised is an intracellular protein.
  • the antibody may be conjugated to a protein which facilitates entry into the cell.
  • the antibody enters the cell by endocytosis.
  • a nucleic acid encoding the antibody is administered to the individual or cell.
  • an antibody thereto may contain a signal for that target localization, e.g., a nuclear localization signal.
  • the cancer antibodies of the invention specifically bind to cancer proteins.
  • “specifically bind” herein is meant that the antibodies bind to the protein with a K ⁇ of at least about 0.1 mM, more usually at least about 1 ⁇ M, preferably at least about 0.1 ⁇ M or better, and most preferably, 0.01 ⁇ M or better. Selectivity of binding to the specific target and not to related sequences is often also important. Detection of cancer sequence for diagnostic and therapeutic applications
  • the RNA expression levels of genes are determined for different cellular states in the cancer phenotype. Expression levels of genes in normal tissue (e.g., not undergoing cancer) and in cancer tissue (and in some cases, for varying severities of cancer that relate to prognosis, as outlined below), or in non-malignant disease are evaluated to provide expression profiles.
  • a gene expression profile of a particular cell state or point of development is essentially a "finge ⁇ rint" of the state of the cell. While two states may have a particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is reflective of the state of the cell.
  • differential expression refers to qualitative or quantitative differences in the temporal and/or cellular gene expression patterns within and among cells and tissue.
  • a differentially expressed gene can qualitatively have its expression altered, including an activation or inactivation, in, e.g., normal versus cancer tissue.
  • Genes may be turned on or turned off in a particular state, relative to another state thus permitting comparison of two or more states.
  • a qualitatively regulated gene will exhibit an expression pattern within a state or cell type which is detectable by standard techniques. Some genes will be expressed in one state or cell type, but not in both.
  • the difference in expression maybe quantitative, e.g., in that expression is increased or decreased; e.g., gene expression is either upregulated, resulting in an increased amount of transcript, or downregulated, resulting in a decreased amount of transcript.
  • the degree to which expression differs need only be large enough to quantify via standard characterization techniques as outlined below, such as by use of Affymetrix GeneChipTM expression anays. See, Lockhart (1996) Nature Biotechnology 14:1675-1680.
  • Other techniques include, but are not limited to, quantitative reverse transcriptase PCR, northern analysis, and RNase protection.
  • the change in expression is at least about 50%), more preferably at least about 100%, more preferably at least about 150%, more preferably at least about 200%, with from 300 to at least 1000% being especially prefened.
  • Evaluation may be at the gene transcript or the protein level.
  • the amount of gene expression may be monitored using nucleic acid probes to the RNA or DNA equivalent of the gene transcript, and the quantification of gene expression levels, or, alternatively, the final gene product itself (protein) can be monitored, e.g., with antibodies to the cancer protein and standard immunoassays (ELIS As, etc.) or other techniques, including mass spectroscopy assays, 2D gel electrophoresis assays, etc.
  • ELIS As standard immunoassays
  • Proteins conesponding to cancer genes can be evaluated in a cancer diagnostic test.
  • gene expression monitoring is performed simultaneously on a number of genes. Multiple protein expression monitoring can be performed as well.
  • the cancer nucleic acid probes are attached to biochips as outlined herein for the detection and quantification of cancer sequences in a particular cell.
  • the assays are further described below in the example. PCR techniques can be used to provide greater sensitivity.
  • nucleic acids encoding the cancer protein are detected.
  • DNA or RNA encoding the cancer protein may be detected, of particular interest are methods wherein an mRNA encoding a cancer protein is detected.
  • Probes to detect mRNA can be a nucleotide/deoxynucleotide probe that is complementary to and hybridizes with the mRNA and includes, but is not limited to, oligonucleotides, cDNA, or RNA. Probes also should contain a detectable label, as defined herein.
  • the mRNA is detected after immobilizing the nucleic acid to be examined on a solid support such as nylon membranes and hybridizing the probe with the sample.
  • RNA probe digoxygenin labeled riboprobe
  • RNA probe that is complementary to the mRNA encoding a cancer protein is detected by binding the digoxygenin with an anti-digoxygenin secondary antibody and developed with nitro blue tetrazolium and 5-bromo-4-chloro-3-indoyl phosphate.
  • various proteins from the three classes of proteins as described herein are used in diagnostic assays.
  • the cancer proteins, antibodies, nucleic acids, modified proteins, and cells containing cancer sequences are used in diagnostic assays. This can be performed on an individual gene or conesponding polypeptide level.
  • the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes and/or conesponding polypeptides.
  • cancer proteins including intracellular, transmembrane, or secreted proteins, find use as markers of cancer, e.g., for prognostic or diagnostic pu ⁇ oses. Detection of these proteins in putative cancer tissue allows for detection, prognosis, or diagnosis of cancer or similar disease, and for selection of therapeutic strategy.
  • antibodies are used to detect cancer proteins.
  • a prefened method separates proteins from a sample by electrophoresis on a gel (typically a denaturing and reducing protein gel, but maybe another type of gel, including isoelectric focusing gels and the like). Following separation of proteins, the cancer protein is detected, e.g., by immunoblotting with antibodies raised against the cancer protein.
  • antibodies to the cancer protein find use in in situ imaging techniques, e.g., in histology. See, e.g., Asai, et al. (eds. 1993) Methods in Cell Biology: Antibodies in Cell Biology (vol. 37) Academic Press.
  • cells are contacted with from one to many antibodies to the cancer protein(s). Following washing to remove nonspecific antibody binding, the presence of the antibody or antibodies is detected.
  • the antibody is detected by incubating with a secondary antibody that contains a detectable label.
  • the primary antibody to the cancer protein(s) contains a detectable label, e.g., an enzyme marker that can act on a substrate.
  • each one of multiple primary antibodies contains a distinct and detectable label. This method finds particular use in simultaneous screening for a plurality of cancer proteins. Many other histological imaging techniques are also provided by the invention.
  • the label is detected in a fluorometer which has the ability to detect and distinguish emissions of different wavelengths.
  • a fluorescence activated cell sorter FACS
  • FACS fluorescence activated cell sorter
  • antibodies find use in diagnosing cancer from blood, serum, plasma, stool, and other samples. Such samples, therefore, are useful as samples to be probed or tested for the presence of cancer proteins.
  • Antibodies can be used to detect a cancer protein by previously described immunoassay techniques including ELISA, immunoblotting (western blotting), immunoprecipitation, BIACORE technology and the like. Conversely, the presence of antibodies may indicate an immune response against an endogenous cancer protein.
  • in situ hybridization of labeled cancer nucleic acid probes to tissue anays is done. For example, anays of tissue samples, including cancer tissue and/or normal tissue, are made.
  • In situ hybridization (see, e.g., Ausubel, supra) is then performed.
  • a diagnosis, a prognosis, or a prediction may be based on the findings. It is further understood that the genes which indicate the diagnosis may differ from those which indicate the prognosis and molecular profiling of the condition of the cells may lead to distinctions between responsive or refractory conditions or may be predictive of outcomes.
  • the cancer proteins, antibodies, nucleic acids, modified proteins, and cells containing cancer sequences are used in prognosis assays.
  • gene expression profiles can be generated that conelate to cancer, clinical, pathological, or other information, in terms of long term prognosis. Again, this may be done on either a protein or gene level, with the use of genes being prefened. Single or multiple genes may be useful in various combinations.
  • cancer probes may be attached to biochips for the detection and quantification of cancer sequences in a tissue or patient. The assays proceed as outlined above for diagnosis. PCR method may provide more sensitive and accurate quantification. Assays for therapeutic compounds
  • the proteins, nucleic acids, and antibodies as described herein are used in drug screening assays.
  • the cancer proteins, antibodies, nucleic acids, modified proteins, and cells containing cancer sequences are used in drug screening assays or by evaluating the effect of drug candidates on a "gene expression profile" or expression profile of polypeptides.
  • the expression profiles are used, preferably in conjunction with high throughput screening techniques, to allow monitoring for expression profile genes after treatment with a candidate agent (e.g., Zlokarnik, et al. (1998) Science 279:84-88; Heid (1996) Genome Res. 6:986-994.
  • the cancer proteins, antibodies, nucleic acids, modified proteins and cells containing the native or modified cancer proteins are used in screening assays. That is, the present invention provides novel methods for screening for compositions which modulate the cancer phenotype or an identified physiological function of a cancer protein. As above, this can be done on an individual gene level or by evaluating the effect of drug candidates on a "gene expression profile".
  • the expression profiles are used, preferably in conjunction with high throughput screening techniques, to allow monitoring for expression profile genes after treatment with a candidate agent, see Zlokarnik, supra.
  • assays may be performed.
  • assays may be run on an individual gene or protein level. That is, having identified a particular gene as up regulated in cancer, test compounds can be screened for the ability to modulate gene expression or for binding to the cancer protein.
  • “Modulation” thus includes both an increase and a decrease in gene expression.
  • the prefened amount of modulation will depend on the original change of the gene expression in normal versus tissue undergoing cancer, with changes of at least 10%, preferably 50%, more preferably 100-300%, and in some embodiments 300-1000% or greater.
  • a gene exhibits a 4-fold increase in cancer tissue compared to normal tissue, a decrease of about four-fold is often desired; similarly, a 10-fold decrease in cancer tissue compared to normal tissue often provides a target value of a 10-fold increase in expression to be induced by the test compound.
  • the amount of gene expression may be monitored using nucleic acid probes and the quantification of gene expression levels, or, alternatively, the gene product itself can be monitored, e.g., through the use of antibodies to the cancer protein and standard immunoassays. Proteomics and separation techniques may also allow quantification of expression.
  • gene expression or protein monitoring of a number of entities e.g., an expression profile
  • Such profiles will typically involve a plurality of those entities described herein.
  • the cancer nucleic acid probes are attached to biochips as outlined herein for the detection and quantification of cancer sequences in a particular cell.
  • PCR may be used.
  • a series e.g., of microtiter plate, may be used with dispensed primers in desired wells. A PCR reaction can then be performed and analyzed for each well.
  • Expression monitoring can be performed to identify compounds that modify the expression of one or more cancer-associated sequences, e.g., a polynucleotide sequence set out in the tables.
  • a test modulator is added to the cells prior to analysis.
  • screens are also provided to identify agents that modulate cancer, modulate cancer proteins, bind to a cancer protein, or interfere with the binding of a cancer protein and an antibody or other binding partner.
  • test compound or “drug candidate” or “modulator” or grammatical equivalents as used herein describes a molecule, e.g., protein, oligopeptide, small organic molecule, polysaccharide, polynucleotide, etc., to be tested for the capacity to directly or indirectly alter the cancer phenotype or the expression of a cancer sequence, e.g., a nucleic acid or protein sequence.
  • modulators alter expression profiles, or expression profile nucleic acids or proteins provided herein.
  • the modulator suppresses a cancer phenotype, e.g., to a normal or non-malignant tissue finge ⁇ rint.
  • a modulator induced a cancer phenotype.
  • a plurality of assay mixtures are run in parallel with different agent concentrations to obtain a differential response to the various concentrations.
  • one of these concentrations serves as a negative control, e.g., at zero concentration or below the level of detection.
  • Drug candidates encompass numerous chemical classes, though typically they are organic molecules, preferably small organic compounds having a molecular weight of more than 100 and less than about 2,500 daltons. Prefened small molecules are less than 2000, or less than 1500, or less than 1000, or less than 500 D.
  • Candidate agents comprise functional groups necessary for structural interaction with proteins, particularly hydrogen bonding, and typically include at least an amine, carbonyl, hydroxyl or carboxyl group, preferably at least two of the functional chemical groups.
  • the candidate agents often comprise cyclical carbon or heterocyclic structures and/or aromatic or polyaromatic structures substituted with one or more of the above functional groups.
  • Candidate agents are also found among biomolecules including peptides, saccharides, fatty acids, steroids, purines, pyrimidines, derivatives, structural analogs, or combinations thereof. Particularly prefened are peptides.
  • a modulator will neutralize the effect of a cancer protein.
  • neutralize is meant that activity of a protein is inhibited or blocked and the consequent effect on the cell.
  • combinatorial libraries of potential modulators will be screened for an ability to bind to a cancer polypeptide or to modulate activity.
  • new chemical entities with useful properties are generated by identifying a chemical compound (called a “lead compound") with some desirable property or activity, e.g., inhibiting activity, creating variants of the lead compound, and evaluating the property and activity of those variant compounds.
  • HTS high throughput screening
  • high throughput screening methods involve providing a library containing a large number of potential therapeutic compounds (candidate compounds). Such "combinatorial chemical libraries” are then screened in one or more assays to identify those library members (particular chemical species or subclasses) that display a desired characteristic activity. The compounds thus identified can serve as conventional "lead compounds” or can themselves be used as potential or actual therapeutics.
  • a combinatorial chemical library is a collection of diverse chemical compounds generated by either chemical synthesis or biological synthesis by combining a number of chemical "building blocks" such as reagents.
  • a linear combinatorial chemical library such as a polypeptide (e.g., mutein) library, is formed by combining a set of chemical building blocks called amino acids in every possible way for a given compound length (e.g., the number of amino acids in a polypeptide compound). Millions of chemical compounds can be synthesized through such combinatorial mixing of chemical building blocks (Gallop, et al. (1994) J. Med. Chem. 37:1233-1251).
  • combinatorial chemical libraries include, but are not limited to, peptide libraries (see, e.g., U.S. Patent No. 5,010,175, Furka (1991) Pept. Prot. Res. 37:487-493, Houghton, et al. (1991) Nature 354:84-88), peptoids (PCT Publication No WO 91/19735), encoded peptides (PCT Publication WO 93/20242), random bio-oligomers (PCT Publication WO 92/00091), benzodiazepines (U.S. Pat. No.
  • the assays to identify modulators are amenable to high throughput screening. Prefened assays thus detect enhancement or inhibition of cancer gene transcription, inhibition, or enhancement of polypeptide expression, and inhibition or enhancement of polypeptide activity.
  • High throughput assays for the presence, absence, quantification, or other properties of particular nucleic acids or protein products are well known.
  • binding assays and reporter gene assays are similarly well known.
  • U.S. Patent No. 5,559,410 discloses high throughput screening methods for proteins
  • U.S. Patent No. 5,585,639 discloses high throughput screening methods for nucleic acid binding (e.g., in anays)
  • U.S. Patent Nos. 5,576,220 and 5,541,061 disclose high throughput methods of screening for ligand/antibody binding.
  • high throughput screening systems are commercially available (see, e.g., Zymark Co ⁇ ., Hopkinton, MA; Air Technical Industries, Mentor, OH; Beckman Instruments, Inc. Fullerton, CA; Precision Systems, Inc., Natick, MA, etc.). These systems typically automate entire procedures, including sample and reagent pipetting, liquid dispensing, timed incubations, and final readings of the microplate in detector(s) appropriate for the assay.
  • These configurable systems provide high throughput and rapid start up as well as a high degree of flexibility and customization. The manufacturers of such systems provide detailed protocols for various high throughput systems.
  • Zymark Co ⁇ provides technical bulletins describing screening systems for detecting the modulation of gene transcription, ligand binding, and the like.
  • modulators are proteins, often naturally occurring proteins or fragments of naturally occurring proteins.
  • cellular extracts containing proteins, or random or directed digests of proteinaceous cellular extracts may be used.
  • libraries of proteins may be made for screening in the methods of the invention.
  • Particularly prefened in this embodiment are libraries of bacterial, fungal, viral, and mammalian proteins, with the latter being prefened, and human proteins being especially prefened.
  • Particularly Useful test compound will be directed to the class of proteins to which the target belongs, e.g., substrates for enzymes or ligands and receptors.
  • modulators are peptides of from about 5-30 amino acids, with from about 5-20 amino acids being prefened, and from about 7-15 being particularly prefened.
  • the peptides may be digests of naturally occurring proteins, random peptides, or "biased” random peptides.
  • randomized or grammatical equivalents herein is meant that each nucleic acid and peptide consists of essentially random nucleotides and amino acids, respectively. Since generally these random peptides (or nucleic acids, discussed below) are chemically synthesized, they may inco ⁇ orate a nucleotide or amino acid at any position.
  • the synthetic process can be designed to generate randomized proteins or nucleic acids, to allow the formation of all or most of the possible combinations over the length of the sequence, thus forming a library of randomized candidate bioactive proteinaceous agents.
  • the library is fully randomized, with no sequence preferences or constants at any position.
  • the library is biased. That is, some positions within the sequence are either held constant, or are selected from a limited number of possibilities.
  • the nucleotides or amino acid residues are randomized within a defined class, e.g., of hydrophobic amino acids, hydrophilic residues, sterically biased (either small or large) residues, towards the creation of nucleic acid binding domains, the creation of cysteines, for cross-linking, prolines for SH-3 domains, serines, threonines, tyrosines, or histidines for phosphorylation sites, etc., or to purines, etc.
  • Modulators of cancer can also be nucleic acids, as defined above.
  • nucleic acid modulating agents may be naturally occurring nucleic acids, random nucleic acids, or "biased" random nucleic acids.
  • digests of prokaryotic or eukaryotic genomes maybe used as is outlined above for proteins.
  • the candidate compounds are organic chemical moieties, a wide variety of which are available in the literature.
  • the sample containing a target sequence to be analyzed is added to the biochip.
  • the target sequence is prepared using known techniques.
  • the sample may be treated to lyse the cells, using known lysis buffers, electroporation, etc., with purification and/or amplification such as PCR performed as appropriate.
  • an in vitro transcription with labels covalently attached to the nucleotides is performed.
  • the nucleic acids are labeled with biotin-FITC or PE, or with cy3 or cy5.
  • the target sequence is labeled with, e.g., a fluorescent, a chemiluminescent, a chemical, or a radioactive signal, to provide a means of detecting the target sequence's specific binding to a probe.
  • the label also can be an enzyme, such as, alkaline phosphatase or horseradish peroxidase, which when provided with an appropriate substrate produces a product that can be detected.
  • the label can be a labeled compound or small molecule, such as an enzyme inhibitor, that binds but is not catalyzed or altered by the enzyme.
  • the label also can be a moiety or compound, such as, an epitope tag or biotin which specifically binds to streptavidin.
  • the streptavidin is labeled as described above, thereby, providing a detectable signal for the bound target sequence. Unbound labeled streptavidin is typically removed prior to analysis.
  • assays can be direct hybridization assays or can comprise "sandwich assays", which include the use of multiple probes, as is generally outlined in U.S. Patent Nos. 5,681,702, 5,597,909, 5,545,730, 5,594,117, 5,591,584, 5,571,670, 5,580,731, 5,571,670, 5,591,584,
  • the target nucleic acid is prepared as outlined above, and then added to the biochip comprising a plurality of nucleic acid probes, under conditions that allow the formation of a hybridization complex.
  • hybridization conditions may be used in the present invention, including high, moderate, and low stringency conditions as outlined above.
  • the assays are generally run under stringency conditions which allows formation of the label probe hybridization complex only in the presence of target. Stringency can be controlled by altering a step parameter that is a thermodynamic variable, including, but not limited to, temperature, formamide concentration, salt concentration, chaofropic salt concentration, pH, organic solvent concentration, etc.
  • the reactions outlined herein may be accomplished in a variety of ways. Components of the reaction may be added simultaneously, or sequentially, in different orders, with prefened embodiments outlined below.
  • the reaction may include a variety of other reagents. These include salts, buffers, neutral proteins, e.g., albumin, detergents, etc. which may be used to facilitate optimal hybridization and detection, and/or reduce non-specific or background interactions. Reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., may also be used as appropriate, depending on the sample preparation methods and purity of the target.
  • the assay data are analyzed to determine the expression levels, and changes in expression levels as between states of individual genes, forming a gene expression profile.
  • Screens are performed to identify modulators of the cancer phenotype.
  • screening is performed to identify modulators that can induce or suppress a particular expression profile, thus preferably generating the associated phenotype.
  • screens can be performed to identify modulators that alter expression of individual genes.
  • screening is performed to identify modulators that alter a biological function of the expression product of a differentially expressed gene. Again, having identified the importance of a gene in a particular state, screens are performed to identify agents that bind and/or modulate the biological activity of the gene product.
  • screens can be done for genes that are induced in response to a candidate agent or treatment process. After identifying a modulator based upon its ability to suppress a cancer expression pattern leading to a normal expression pattern (or its converse), or to modulate a single cancer gene expression profile so as to mimic the expression of the gene from normal tissue, a screen as described above can be performed to identify genes that are specifically modulated in response to the agent. Comparing expression profiles between normal tissue and agent treated cancer tissue reveals genes that are not expressed in normal tissue or cancer tissue, but are expressed in agent treated tissue.
  • agent-specific sequences can be identified and used by methods described herein for cancer genes or proteins. In particular, these sequences and the proteins they encode find use in marking or identifying agent treated cells.
  • antibodies can be raised against the agent induced proteins and used to target novel therapeutics, e.g., toxin loaded liposomes, to the treated cancer tissue sample.
  • a test compound is administered to a population of cancer cells that have an associated cancer expression profile.
  • administration or “contacting” herein is meant that the candidate agent is added to the cells in such a manner as to allow the agent to act upon the cell, whether by uptake and intracellular action, or by action at the cell surface.
  • nucleic acid encoding a proteinaceous candidate agent e.g., a peptide
  • a viral construct such as an adenoviral or retroviral construct
  • Regulatable gene therapy systems can also be used.
  • cancer or non-malignant tissue may be screened for agents that modulate, e.g., induce or suppress a cancer phenotype.
  • a change in at least one gene, preferably many, of the expression profile indicates that the agent has an effect on cancer activity.
  • screens may be done on individual genes and gene products (proteins). That is, having identified a particular differentially expressed gene as important in a particular state, screening of modulators of either the expression of the gene or the gene product itself can be done.
  • the gene products of differentially expressed genes are sometimes refened to herein as "cancer proteins” or a "cancer modulatory protein".
  • the cancer modulatory protein may be a fragment, or alternatively, be the full length protein to the fragment encoded by the nucleic acids of the Tables.
  • the cancer modulatory protein is a fragment.
  • the cancer amino acid sequence which is used to determine sequence identity or similarity is encoded by a nucleic acid of the Tables.
  • the sequences are naturally occurring allelic variants of a protein encoded by a nucleic acid of the Tables.
  • the sequences are sequence variants as further described herein.
  • the cancer modulatory protein is a fragment of about 14-24 amino acids long. More preferably the fragment is a soluble fragment. Preferably, the fragment includes a non-fransmembrane region. In a prefened embodiment, the fragment has an N-terminal Cys to aid in solubility. In one embodiment, the C-terminus of the fragment is kept as a free acid and the N-terminus is a free amine to aid in coupling, e.g., to cysteine. In one embodiment the cancer proteins are conjugated to an immunogenic agent as discussed herein. In one embodiment the cancer protein is conjugated to BSA.
  • Measurements of cancer polypeptide activity, or of cancer or the cancer phenotype can be performed using a variety of assays.
  • the effects of the test compounds upon the function of the cancer polypeptides can be measured by examining parameters described above.
  • a suitable physiological change that affects activity can be used to assess the influence of a test compound on the polypeptides of this invention.
  • cancer polypeptide is typically used, e.g., mouse, preferably human.
  • Assays to identify compounds with modulating activity can be performed in vitro.
  • a cancer polypeptide is first contacted with a potential modulator and incubated for a suitable amount of time, e.g., from 0.5-48 hours.
  • the cancer polypeptide levels are determined in vitro by measuring the level of protein or mRNA.
  • the level of protein is typically measured using immunoassays such as western blotting, ELISA, and the like with an antibody that selectively binds to the cancer polypeptide or a fragment thereof.
  • amplification e.g., using PCR, LCR, or hybridization assays, e.g., northern hybridization, RNAse protection, dot blotting
  • the level of protein or mRNA is typically detected using directly or indirectly labeled detection agents, e.g., fluorescently or radioactively labeled nucleic acids, radioactively or enzymatically labeled antibodies, and the like, as described herein.
  • a reporter gene system can be devised using a cancer protein promoter operably linked to a reporter gene such as luciferase, green fluorescent protein, CAT, or ⁇ -gal. The reporter construct is typically transfected into a cell.
  • the amount of reporter gene transcription, translation, or activity is measured according to standard techniques.
  • screens may be done on individual genes and gene products (proteins). That is, having identified a particular differentially expressed gene as important in a particular state, screening of modulators of the expression of the gene or the gene product itself can be done.
  • the gene products of differentially expressed genes are sometimes refened to herein as "cancer proteins.”
  • the cancer protein may be a fragment, or alternatively, the full length protein to a fragment shown herein.
  • screening for modulators of expression of specific genes is performed. Typically, the expression of only one or a few genes are evaluated. In another embodiment, screens are designed to first find compounds that bind to differentially expressed proteins. These compounds are then evaluated for the ability to modulate differentially expressed activity. Moreover, once initial candidate compounds are identified, variants can be further screened to better evaluate structure activity relationships. In a prefened embodiment, binding assays are done. In general, purified or isolated gene product is used; that is, the gene products of one or more differentially expressed nucleic acids are made. For example, antibodies are generated to the protein gene products, and standard immunoassays are run to determine the amount of protein present. Alternatively, cells comprising the cancer proteins can be used in the assays.
  • the methods comprise combining a cancer protein and a candidate compound, and determining the binding of the compound to the cancer protein.
  • Prefened embodiments utilize the human cancer protein, although other mammalian proteins may also be used, e.g., for the development of animal models of human disease.
  • variant or derivative cancer proteins may be used.
  • the cancer protein or the candidate agent is non-diffusably bound to an insoluble support, preferably having isolated sample receiving areas (e.g., a microtiter plate, an anay, etc.).
  • the insoluble supports may be made of a composition to which the compositions can be bound, is readily separated from soluble material, and is otherwise compatible with the overall method of screening.
  • the surface of such supports may be solid or porous and of a convenient shape.
  • suitable insoluble supports include microtiter plates, anays, membranes, and beads. These are typically made of glass, plastic (e.g., polystyrene), polysaccharides, nylon or nitrocellulose, teflonTM, etc. Microtiter plates and anays are especially convenient because a large number of assays can be carried out simultaneously, using small amounts of reagents and samples.
  • the particular manner of binding of the composition is typically not crucial so long as it is compatible with the reagents and overall methods of the invention, maintains the activity of the composition, and is nondiffusable.
  • Prefened methods of binding include the use of antibodies (which do not sterically block either the ligand binding site or activation sequence when the protein is bound to the support), direct binding to "sticky" or ionic supports, chemical crosslinking, the synthesis of the protein or agent on the surface, etc. Following binding of the protein or agent, excess unbound material is removed by washing. The sample receiving areas may then be blocked through incubation with bovine serum albumin (BSA), casein, or other innocuous protein or other moiety.
  • BSA bovine serum albumin
  • the cancer protein is bound to the support, and a test compound is added to the assay.
  • the candidate agent is bound to the support and the cancer protein is added.
  • Novel binding agents include specific antibodies, non-natural binding agents identified in screens of chemical libraries, peptide analogs, etc. Of particular interest are screening assays for agents that have a low toxicity for human cells. A wide variety of assays may be used for this pu ⁇ ose, including labeled in vitro protein-protein binding assays, electrophoretic mobility shift assays, immunoassays for protein binding, functional assays (phosphorylation assays, etc.), and the like.
  • the determination of the binding of the test modulating compound to the cancer protein may be done in a number of ways.
  • the compound is labeled, and binding determined directly, e.g., by attaching all or a portion of the cancer protein to a solid support, adding a labeled candidate agent (e.g., a fluorescent label), washing off excess reagent, and determimng whether the label is present on the solid support.
  • a labeled candidate agent e.g., a fluorescent label
  • washing off excess reagent e.g., a fluorescent label
  • determimng whether the label is present on the solid support.
  • Various blocking and washing steps may be utilized as appropriate.
  • the proteins can be labeled.
  • more than one component can be labeled with different labels, e.g., 125j f or fl ⁇ p ro teins and a fluorophor for the compound.
  • Proximity reagents e.g., quenching or energy transfer reagents are also useful.
  • the binding of the test compound is determined by competitive binding assay.
  • the competitor may be a binding moiety known to bind to the target molecule (e.g., a cancer protein), such as an antibody, peptide, binding partner, ligand, etc.
  • the test compound is labeled. Either the compound, or the competitor, or both, is added first to the protein for a time sufficient to allow binding, if present. Incubations may be performed at a temperature which facilitates optimal activity, typically between about 4-40° C. Incubation periods are typically optimized, e.g., to facilitate rapid high throughput screening. Typically between 0.1-1 hour will be sufficient. Excess reagent is generally removed or washed away. The second component is then added, and the presence or absence of the labeled component is followed, to indicate binding. In a prefened embodiment, the competitor is added first, followed by a test compound.
  • Displacement of the competitor is an indication that the test compound is binding to the cancer protein and thus is capable of binding to, and potentially modulating, the activity of the cancer protein.
  • either component can be labeled.
  • the presence of label in the wash solution indicates displacement by the agent.
  • the presence of the label on the support indicates displacement.
  • test compound is added first, with incubation and washing, followed by the competitor.
  • the absence of binding by the competitor may indicate that the test compound is bound to the cancer protein with a higher affinity.
  • the presence of the label on the support, coupled with a lack of competitor binding may indicate that the test compound is capable of binding to the cancer protein.
  • the methods comprise differential screening to identity agents that are capable of modulating the activity of the cancer proteins.
  • the methods comprise combining a cancer protein and a competitor in a first sample.
  • a second sample comprises a test compound, a cancer protein, and a competitor.
  • the binding of the competitor is determined for both samples, and a change, or difference in binding between the two samples indicates the presence of an agent capable of binding to the cancer protein arid potentially modulating its activity. That is, if the binding of the competitor is different in the second sample relative to the first sample, the agent is capable of binding to the cancer protein.
  • differential screening is used to identify drug candidates that bind to the native cancer protein, but cannot bind to modified cancer proteins.
  • the structure of the cancer protein may be modeled, and used in rational drug design to synthesize agents that interact with that site.
  • Drug candidates that affect the activity of a cancer protein are also identified by screening drugs for the ability to either enhance or reduce the activity of the protein.
  • Positive controls and negative controls may be used in the assays.
  • confrol and test samples are performed in at least triplicate to obtain statistically significant results. Incubation of all samples is for a time sufficient for the binding of the agent to the protein. Following incubation, samples are washed free of non-specifically bound material and the amount of bound, generally labeled agent determined. For example, where a radiolabel is employed, the samples may be counted in a scintillation counter to determine the amount of bound compound.
  • reagents may be included in the screening assays. These include reagents like salts, neutral proteins, e.g., albumin, detergents, etc., which may be used to facilitate optimal protein-protein binding and/or reduce non-specific or background interactions. Also reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., maybe used. The mixture of components may be added in an order that provides for the requisite binding.
  • the invention provides methods for screening for a compound capable of modulating the activity of a cancer protein.
  • the methods comprise adding a test compound, as defined above, to a cell comprising cancer proteins.
  • Prefened cell types include almost any cell.
  • the cells contain a recombinant nucleic acid that encodes a cancer protein.
  • a library of candidate agents are tested on a plurality of cells.
  • the assays are evaluated in the presence or absence or previous or subsequent exposure of physiological signals, e.g., hormones, antibodies, peptides, antigens, cytokines, growth factors, action potentials, pharmacological agents including chemotherapeutics, radiation, carcinogenics, or other cells (e.g., cell-cell contacts).
  • physiological signals e.g., hormones, antibodies, peptides, antigens, cytokines, growth factors, action potentials, pharmacological agents including chemotherapeutics, radiation, carcinogenics, or other cells (e.g., cell-cell contacts).
  • the determinations are determined at different stages of the cell cycle process.
  • a method of inhibiting cancer cell division comprises administration of a cancer inhibitor.
  • a method of inhibiting cancer is provided.
  • the method may comprise adminisfration of a cancer inhibitor.
  • methods of treating cells or individuals with cancer are provided, e.g., comprising administration of a cancer inhibitor.
  • a cancer inhibitor is an antibody as discussed above. In another embodiment, the cancer inhibitor is an antisense molecule.
  • a variety of cell growth, proliferation, viability, and metastasis assays are available, as described below. Soft agar growth or colony formation in suspension
  • Normal cells require a solid substrate to attach and grow. When the cells are transformed, they lose this phenotype and grow detached from the substrate.
  • transformed cells can grow in stined suspension culture or suspended in semi-solid media, such as semi-solid or soft agar.
  • the transformed cells when transfected with tumor suppressor genes, regenerate normal phenotype and require a solid substrate to attach and grow.
  • Soft agar growth or colony formation in suspension assays can be used to identify modulators of cancer sequences, which when expressed in host cells, inhibit abnormal cellular proliferation and transformation.
  • a therapeutic compound would reduce or eliminate the host cells' ability to grow in stined suspension culture or suspended in semi-solid media, such as semi-solid or soft.
  • Normal cells typically grow in a flat and organized pattern in a petri dish until they touch other cells. When the cells touch one another, they are contact inhibited and stop growing. When cells are transformed, however, the cells are not contact inhibited and continue to grow to high densities in disorganized foci. Thus, the transformed cells grow to a higher saturation density than normal cells. This can be detected mo ⁇ hologically by the formation of a disoriented monolayer of cells or rounded cells in foci within the regular pattern of normal sunounding cells. Alternatively, labeling index with (3H)-thymidine at saturation density can be used to measure density limitation of growth. See Freshney (2000), supra. The transformed cells, when transfected with tumor suppressor genes, regenerate a normal phenotype and become contact inhibited and would grow to a lower density.
  • labeling index with (3H)-thymidine at saturation density is a prefened method of measuring density limitation of growth.
  • Transformed host cells are transfected with a cancer-associated sequence and are grown for 24 hours at saturation density in non-limiting medium conditions.
  • the percentage of cells labeling with (3H)-thymidine is determined autoradiographically. See, Freshney (1998), supra. Growth factor or serum dependence
  • Transformed cells typically have a lower serum dependence than their normal counte ⁇ arts (see, e.g., Temin (1966) J. Natl. Cancer Insti. 37:167-175; Eagle, et al.(1970) J.
  • Tumor cells release an increased amount of certain factors (hereinafter “tumor specific markers”) than their normal counte ⁇ arts.
  • tumor specific markers For example, plasminogen activator (PA) is released from human glioma at a higher level than from normal brain cells (see, e.g., Gullino
  • tumor angiogenesis factor (TAF) is released at a higher level in tumor cells than their normal counte ⁇ arts. See, e.g., Folkman (1992) Sem. Cancer Biol. 3:89-96. Various techniques which measure the release of these factors are described in Freshney
  • the degree of invasiveness into Matrigel or some other extracellular matrix constituent can be used as an assay to identify compounds that modulate cancer-associated sequences.
  • Tumor cells exhibit a good conelation between malignancy and invasiveness of cells into Matrigel or some other exfracellular matrix constituent.
  • tumorigenic cells are typically used as host cells. Expression of a tumor suppressor gene in these host cells would decrease invasiveness of the host cells.
  • the level of invasion of host cells can be measured by using filters coated with Matrigel or some other exfracellular matrix constituent. Penefration into the gel, or through to the distal side of the filter, is rated as invasiveness, and rated histologically by number of cells and distance moved, or by prelabeling the cells with 125j and counting the radioactivity on the distal side of the filter or bottom of the dish. See, e.g., Freshney (1984), supra. Tumor growth in vivo
  • Knock-out transgenic mice can be made, in which the cancer gene is disrupted or in which a cancer gene is inserted.
  • Knock-out transgenic mice can be made by insertion of a marker gene or other heterologous gene into the endogenous cancer gene site in the mouse genome via homologous recombination.
  • Such mice can also be made by substituting the endogenous cancer gene with a mutated version of the cancer gene, or by mutating the endogenous cancer gene, e.g., by exposure to carcinogens.
  • a DNA construct is introduced into the nuclei of embryonic stem cells.
  • Cells containing the newly engineered genetic lesion are injected into a host mouse embryo, which is re- implanted into a recipient female. Some of these embryos develop into chimeric mice that possess germ cells partially derived from the mutant cell line. Therefore, by breeding the chimeric mice it is possible to obtain a new line of mice containing the introduced genetic lesion (see, e.g., Capecchi, et al. (1989) Science 244:1288-1292).
  • Chimeric targeted mice can be derived according to Hogan, et al. (1988) Manipulating the Mouse Embryo: A Laboratory Manual CSH Press; and Robertson (ed.
  • Transplantable tumor cells typically about 10 ⁇ cells
  • injected into isogenic hosts will produce invasive tumors in a high proportions of cases, while normal cells of similar origin will not.
  • cells expressing a cancer-associated sequences are injected subcutaneously.
  • tumor growth is measured (e.g., by volume or by its two largest dimensions) and compared to the control. Tumors that have statistically significant reduction (using, e.g., Student's T test) are said to have inhibited growth.
  • the activity of a cancer-associated protein is down-regulated, or entirely inhibited, by the use of an inhibitory or antisense polynucleotide, e.g., a nucleic acid complementary to, and which can preferably hybridize specifically to, a coding mRNA nucleic acid sequence, e.g., a cancer protein mRNA, or a subsequence thereof. Binding of the antisense polynucleotide to the mRNA reduces the translation and/or stability of the mRNA.
  • an inhibitory or antisense polynucleotide e.g., a nucleic acid complementary to, and which can preferably hybridize specifically to, a coding mRNA nucleic acid sequence, e.g., a cancer protein mRNA, or a subsequence thereof. Binding of the antisense polynucleotide to the mRNA reduces the translation and/or stability of the mRNA.
  • antisense polynucleotides can comprise naturally- occurring nucleotides, or synthetic species formed from naturally-occurring subunits or their close homologs. Antisense polynucleotides may also have altered sugar moieties or inter-sugar linkages. Exemplary among these are the phosphorothioate and other sulfur containing species. Analogs are comprehended by this invention so long as they function effectively to hybridize with the cancer protein mRNA. See, e.g., Isis Pharmaceuticals, Carlsbad, CA; Sequitor, Inc., Natick, MA. Such antisense polynucleotides can readily be synthesized using recombinant means, or can be synthesized in vitro. Equipment for such synthesis is sold by several vendors, including Applied Biosystems. The preparation of other oligonucleotides such as phosphorothioates and alkylated derivatives is also well known.
  • Antisense molecules as used herein include antisense or sense oligonucleotides.
  • Sense oligonucleotides can, e.g., be employed to block transcription by binding to the anti-sense strand.
  • the antisense and sense oligonucleotide comprise a single-stranded nucleic acid sequence (either RNA or DNA) capable of binding to target mRNA (sense) or DNA (antisense) sequences for cancer molecules.
  • a prefened antisense molecule is for a cancer sequences in the Tables, or for a ligand or activator thereof.
  • Antisense or sense oligonucleotides comprise a fragment generally at least about 14 nucleotides, preferably from about 14-30 nucleotides.
  • the ability to derive an antisense or a sense oligonucleotide, based upon a cDNA sequence encoding a given protein is described in, e.g., Stein and Cohen (1988) Cancer Res. 48:2659-2668; and van der Krol, et al. (1988) BioTechniques 6:958-976.
  • RNA interference is a mechanism to suppress gene expression in a sequence specific manner. See, e.g., Brumelkamp, et al.
  • RNAi double stranded small interfering RNAs
  • Ribozymes In addition to antisense polynucleotides, ribozymes can be used to target and inhibit transcription of cancer-associated nucleotide sequences.
  • a ribozyme is an RNA molecule that catalytically cleaves other RNA molecules.
  • Different kinds of ribozymes have been described, including group I ribozymes, hammerhead ribozymes, hai ⁇ in ribozymes, RNase P, and axhead ribozymes (see, e.g., Castanotto, et al. (1994) Adv. in Pharmacology 25: 289-317 for a general review of the properties of different ribozymes).
  • hai ⁇ in ribozymes are described, e.g., in Hampel, et al. (1990) Nucl. Acids Res. 18:299-304; European Patent Publication No. 0 360257; U.S. Patent No. 5,254,678. Methods of preparation are described in, e.g., WO 94/26877; Ojwang, et al. (1993) Proc. Natl. Acad. Sci. USA 90:6340-6344; Yamada, et al. (1994) Human Gene Therapy 1:39- 45; Leavitt, et al.(1995) Proc. Natl. Acad. Sci. USA 92:699-703; Leavitt, et al. (1994) Human Gene Therapy 5:1151-120; and Yamada, et al. (1994) Virology 205: 121-126.
  • Polynucleotide modulators of cancer may be introduced into a cell containing the target nucleotide sequence by formation of a conjugate with a ligand binding molecule, as described in WO 91/04753.
  • Suitable ligand binding molecules include, but are not limited to, cell surface receptors, growth factors, other cytokines, or other ligands that bind to cell surface receptors.
  • conjugation of the ligand binding molecule does not substantially interfere with the ability of the ligand binding molecule to bind to its conesponding molecule or receptor, dr block entry of the sense or antisense oligonucleotide or its conjugated version into the cell.
  • a polynucleotide modulator of cancer may be introduced into a cell containing the target nucleic acid sequence, e.g., by formation of an polynucleotide-lipid complex, as described in WO 90/10448. It is understood that the use of antisense molecules or knock out and knock in models may also be used in screening assays as discussed above, in addition to methods of freatment.
  • methods of modulating cancer in cells or organisms comprise administering to a cell an anti-cancer antibody that reduces or eliminates the biological activity of an endogenous cancer protein.
  • the methods comprise administering to a cell or organism a recombinant nucleic acid encoding a cancer protein. This may be accomplished in any number of ways. In a prefened embodiment, e.g., when the cancer sequence is down-regulated in cancer, such state may be reversed by increasing the amount of cancer gene product in the cell. This can be accomplished, e.g., by overexpressing the endogenous cancer gene or administering a gene encoding the cancer sequence, using known gene-therapy techniques.
  • the gene therapy techniques include the inco ⁇ oration of the exogenous gene using enhanced homologous recombination (EHR), e.g., as described in PCT/US93/0386.
  • EHR enhanced homologous recombination
  • the cancer sequence is up-regulated in cancer
  • the activity of the endogenous cancer gene is decreased, e.g., by the administration of a cancer antisense or other inhibitor, e.g., RNAi.
  • the cancer proteins of the present invention may be used to generate polyclonal and monoclonal antibodies to cancer proteins.
  • the cancer proteins can be coupled, using standard technology, to affinity chromatography columns. These columns may then be used to purify cancer antibodies useful for production, diagnostic, or therapeutic piuposes.
  • the antibodies are generated to epitopes unique to a cancer protein; that is, the antibodies show little or no cross-reactivity to other proteins.
  • the cancer antibodies may be coupled to standard affinity chromatography columns and used to purify cancer proteins.
  • the antibodies may also be used as blocking polypeptides, as outlined above, since they will specifically bind to the cancer protein.
  • the invention provides methods for identifying cells containing variant cancer genes, e.g., determining all or part of the sequence of at least one endogenous cancer gene in a cell.
  • the invention provides methods of identifying the cancer genotype of an individual, e.g., determining all or part of the sequence of at least one cancer gene of the individual. This is generally done in at least one tissue of the individual, and may include the evaluation of a number of tissues or different samples of the same tissue.
  • the method may include comparing the sequence of the sequenced cancer gene to a known cancer gene, e.g., a wild-type gene.
  • the sequence of all or part of the cancer gene can then be compared to the sequence of a known cancer gene to determine if any differences exist. This can be done using known homology programs, such as Bestfit, etc.
  • known homology programs such as Bestfit, etc.
  • the presence of a difference in the sequence between the cancer gene of the patient and the known cancer gene conelates with a disease state or a propensity for a disease state, as outlined herein.
  • the cancer genes are used as probes to determine the number of copies of the cancer gene in the genome.
  • the cancer genes are used as probes to determine the chromosomal localization of the cancer genes.
  • Information such as chromosomal localization finds use in providing a diagnosis or prognosis in particular when chromosomal abnormalities such as translocations, and the like are identified in the cancer gene locus.
  • a therapeutically effective dose of a cancer protein or modulator thereof is administered to a patient.
  • therapeutically effective dose herein is meant a dose that produces effects for which it is administered. The exact dose will depend on the pu ⁇ ose of the freatment, and will be ascertainable using known techniques. See, e.g., Ansel, et al. (1999) Pharmaceutical Dosage Forms and Drug Delivery Lippincott; Lieberman (1992) Pharmaceutical Dosage Forms (vols. 1-3) Dekker, ISBN 0824770846, 082476918X, 0824712692, 0824716981; Lloyd (1999) The Art, Science and Technology of Pharmaceutical Compounding Amer. Pharmaceut.
  • a "patient” for the pu ⁇ oses of the present invention includes both humans and other animals, particularly mammals. Thus the methods are applicable to both human therapy and veterinary applications.
  • the patient is a mammal, preferably a primate, and in the most prefened embodiment the patient is human.
  • the administration of the cancer proteins and modulators thereof of the present invention can be done in a variety of ways, including, but not limited to, orally, subcutaneously, intravenously, intranasally, transdermally, intraperitoneally, intramuscularly, intrapulmonary, vaginally, rectally, or infraocularly.
  • the cancer proteins and modulators may be directly applied as a solution or spray.
  • the pharmaceutical compositions of the present invention comprise a cancer protein in a form suitable for administration to a patient.
  • the pharmaceutical compositions are in a water soluble form, such as being present as pharmaceutically acceptable salts, which is meant to include both acid and base addition salts.
  • “Pharmaceutically acceptable acid addition salt” refers to those salts that retain the biological effectiveness of the free bases and that are not biologically or otherwise undesirable, formed with inorganic acids such as hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, and the like, and organic acids such as acetic acid, propionic acid, glycolic acid, pyruvic acid, oxalic acid, maleic acid, malonic acid, succinic acid, fumaric acid, tartaric acid, citric acid, benzoic acid, cinnamic acid, mandelic acid, methanesulfonic acid, ethanesulfonic acid, p-toluenesulfonic acid, salicylic acid, and the like.
  • inorganic acids such as hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, and the like
  • organic acids such as acetic acid, propionic acid, glycolic acid, pyruvic
  • “Pharmaceutically acceptable base addition salts” include those derived from inorganic bases such as sodium, potassium, lithium, ammonium, calcium, magnesium, iron, zinc, copper, manganese, aluminum salts, and the like. Particularly prefened are the ammonium, potassium, sodium, calcium, and magnesium salts. Salts derived from pharmaceutically acceptable organic non-toxic bases include salts of primary, secondary, and tertiary amines, substituted amines including naturally occurring substituted amines, cyclic amines and basic ion exchange resins, such as isopropylamine, trimethylamine, diethylamine, triethylamine, tripropylamine, and ethanolamine.
  • compositions may also include one or more of the following: carrier proteins such as serum albumin; buffers; fillers such as microcrystalline cellulose, lactose, corn and other starches; binding agents; sweeteners and other flavoring agents; coloring agents; and polyethylene glycol.
  • compositions can be administered in a variety of unit dosage forms depending upon the method of administration.
  • unit dosage forms suitable for oral adminisfration include, but are not limited to, powder, tablets, pills, capsules and lozenges.
  • cancer protein modulators e.g., antibodies, antisense constructs, ribozymes, small organic molecules, etc.
  • This is typically accomplished either by complexing the molecule(s) with a composition to render it resistant to acidic and enzymatic hydrolysis, or by packaging the molecule(s) in an appropriately resistant carrier, such as a liposome or a protection barrier. Means of protecting agents from digestion are available.
  • compositions for administration will commonly comprise a cancer protein modulator dissolved in a pharmaceutically acceptable carrier, preferably an aqueous carrier.
  • a pharmaceutically acceptable carrier preferably an aqueous carrier.
  • aqueous carriers can be used, e.g., buffered saline and the like. These solutions are sterile and generally free of undesirable matter.
  • These compositions may be sterilized by conventional, well known sterilization techniques.
  • the compositions may contain pharmaceutically acceptable auxiliary substances as required to approximate physiological conditions such as pH adjusting and buffering agents, toxicity adjusting agents, and the like, e.g., sodium acetate, sodium chloride, potassium chloride, calcium chloride, sodium lactate, and the like.
  • concentration of active agent in these formulations can vary widely, and will be selected primarily based on fluid volumes, viscosities, body weight, and the like in accordance with the particular mode of administration selected and the patient's needs (e.g., (1980) Remington's Pharmaceutical Science (18th ed.) Mack, and Hardman and Limbird (eds. 2001) Goodman and Gilman: The Pharmacological Basis of Therapeutics (10th ed.) McGraw-Hill.
  • a typical pharmaceutical composition for intravenous administration would be about 0.1 to 10 mg per patient per day.
  • compositions containing modulators of cancer proteins can be administered for therapeutic or prophylactic treatments.
  • compositions are administered to a patient suffering from a disease (e.g., a cancer) in an amount sufficient ' to cure or at least partially anest the disease and its complications.
  • a disease e.g., a cancer
  • a therapeutically effective dose An amount adequate to accomplish this is defined as a "therapeutically effective dose.” Amounts effective for this use will depend upon the severity of the disease and the general state of the patient's health. Single or multiple administrations of the compositions may be administered depending on the dosage and frequency as required and tolerated by the patient. In any event, the composition should provide a sufficient quantity of the agents of this invention to effectively treat the patient.
  • An amount of modulator that is capable of preventing or slowing the development of cancer in a mammal is refened to as a "prophylactically effective dose.” The particular dose required for a prophylactic treatment will depend upon the medical condition and history of the mammal, the particular cancer being prevented, as well as other factors such as age, weight, gender, administration route, efficiency, etc.
  • Such prophylactic treatments may be used, e.g., in a mammal who has previously had cancer to prevent a recunence of the cancer, or in a mammal who is suspected of having a significant likelihood of developing cancer based, at least in part, upon gene expression profiles.
  • Vaccine strategies may be used, in either a DNA vaccine form, or protein vaccine.
  • cancer protein-modulating compounds can be administered alone or in combination with additional cancer modulating compounds or with other therapeutic agent, e.g., other anti-cancer agents or treatments.
  • one or more nucleic acids e.g., polynucleotides comprising nucleic acid sequences set forth in the Tables, such as RNAi, antisense polynucleotides or ribozymes, will be introduced into cells, in vitro or in vivo.
  • the present invention provides methods, reagents, vectors, and cells useful for expression of cancer-associated polypeptides and nucleic acids using in vitro (cell-free), ex vivo or in vivo (cell or organism-based) recombinant expression systems.
  • the particular procedure used to introduce the nucleic acids into a host cell for expression of a protein or nucleic acid is application specific.
  • cancer proteins and modulators are administered as therapeutic agents, and can be formulated as outlined above.
  • cancer genes (including both the full-length sequence, partial sequences, or regulatory sequences of the cancer coding regions) can be administered in a gene therapy application. These cancer genes can include inhibitory applications, e.g., as inhibitory RNA, gene therapy (e.g., for inco ⁇ oration into the genome), or antisense compositions.
  • Cancer polypeptides and polynucleotides can also be administered as Vaccine compositions to stimulate HTL, CTL, and antibody responses.
  • Such vaccine compositions can include, e.g., lipidated peptides (see, e.g.Nitiello, et al. (1995) J. Clin. Invest. 95:341-349), peptide compositions encapsulated in poly(DL-lactide-co-glycolide) ("PLG”) microspheres (see, e.g., Eldridge, et al. (1991) Molec. hnmunol. 28:287-294,; Alonso, et al. (1994) Vaccine 12:299-306; Jones, et al.
  • Vaccine 13:675-681 peptide compositions contained in immune stimulating complexes (ISCOMS) (see, e.g., Takahashi, et al. (1990) Nature 344:873- 875; Hu, et al. (1998) Clin Exp Immunol. 113:235-243), multiple antigen peptide systems (MAPs) (see, e.g., Tarn (1988) Proc. Natl. Acad. Sci. USA 85:5409-5413; Tarn (1996) Immunol.
  • ISCOMS immune stimulating complexes
  • MAPs multiple antigen peptide systems
  • Toxin-targeted delivery technologies also known as receptor mediated targeting, such as those of Avant hnmunotherapeutics, Inc. (Needham, Massachusetts) may also be used.
  • Vaccine compositions often include adjuvants.
  • Many adjuvants contain a substance designed to protect the antigen from rapid catabolism, such as aluminum hydroxide or mineral oil, and a stimulator of immune responses, such as lipid A, Bortadella pertussis, or .
  • lipid A lipid A
  • Bortadella pertussis or .
  • Mycobacterium tuberculosis derived proteins are often include adjuvants.
  • adjuvants are commercially available as, e.g., Freund's Incomplete Adjuvant and Complete Adjuvant (Difco Laboratories, Detroit, MI); Merck Adjuvant 65 (Merck and Company, Inc., Rahway, NJ); AS-2 (SmithKline Beecham, Philadelphia, PA); aluminum salts such as aluminum hydroxide gel (alum) or aluminum phosphate; salts of calcium, iron, or zinc; an insoluble suspension of acylated tyrosine; acylated sugars; cationically or anionically derivatized polysaccharides; polyphosphazenes; biodegradable microspheres; monophosphoryl lipid A and quil A.
  • Cytokines such as GM-CSF, interleukin-2, -7, -12, and other like growth factors, may also be used as adjuvants.
  • Vaccines can be administered as nucleic acid compositions wherein DNA or RNA encoding one or more of the polypeptides, or a fragment thereof, is administered to a patient.
  • This approach is described, for instance, in Wolff et. al. (1990) Science 247:1465-1468, as well as U.S. Patent Nos. 5,580,859; 5,589,466; 5,804,566; 5,739,118; 5,736,524; 5,679,647; WO 98/04720; and in more detail below.
  • DNA-based delivery technologies include "naked DNA”, facilitated (bupivicaine, polymers, peptide-mediated) delivery, cationic lipid complexes, and particle-mediated (“gene gun”) or pressure-mediated delivery (see, e.g., U.S. Patent No. 5,922,687).
  • the peptides of the invention can be expressed by viral or bacterial vectors.
  • expression vectors include attenuated viral hosts, such as vaccinia or fowlpox. This approach involves the use of vaccinia virus, e.g., as a vector to express nucleotide sequences that encode cancer polypeptides or polypeptide fragments. Upon introduction into a host, the recombinant vaccinia virus expresses the immunogenic peptide, and thereby elicits an immune response.
  • Vaccinia vectors and methods useful in immunization protocols are described in, e.g., U.S. Patent No. 4,722,848.
  • BCG Bacille Calmette Guerin
  • BCG vectors are described in Stover, et al. (1991) Nature 351 :456-460.
  • a wide variety of other vectors are availablel for therapeutic administration or immunization, e.g., adeno and adeno-associated virus vectors, retroviral vectors, Salmonella typhi vectors, detoxified anthrax toxin vectors, and the like. See, e.g., Shata, et al. (2000) Mol Med Today 6:66-71; Shedlock, et al. (2000) J. Leukoc. Biol. 68:793- 806; Hipp, et al. (2000) In Vivo 14:571-85.
  • Methods for the use of genes as DNA vaccines are well known, and include placing a cancer gene or portion of a cancer gene under the control of a regulatable promoter or a tissue- specific promoter for expression in a cancer patient.
  • the cancer gene used for DNA vaccines can encode full-length cancer proteins, but more preferably encodes portions of the cancer proteins including peptides derived from the cancer protein.
  • a patient is immunized with a DNA vaccine comprising a plurality of nucleotide sequences derived from a cancer gene.
  • cancer-associated genes or sequence encoding subfragments of a cancer protein are introduced into expression vectors and tested for their immunogenicity in the context of Class I MHC and an ability to generate cytotoxic T cell responses. This procedure provides for production of cytotoxic T cell responses against cells which present antigen, including intracellular epitopes.
  • DNA vaccines include a gene encoding an adjuvant molecule with the DNA vaccine.
  • adjuvant molecules include cytokines that increase the immunogenic response to the cancer polypeptide encoded by the DNA vaccine. Additional or alternative adjuvants are available.
  • cancer genes find use in generating animal models of cancer.
  • gene therapy technology e.g., wherein inhibitory or antisense RNA directed to the cancer gene will also diminish or repress expression of the gene.
  • Animal models of cancer find use in screening for modulators of a cancer-associated sequence or modulators of cancer.
  • transgenic animal technology including gene knockout technology, e.g., as a result of homologous recombination with an appropriate gene targeting vector, will result in the absence or increased expression of the cancer protein.
  • tissue-specific expression or knockout of the cancer protein may be necessary.
  • the cancer protein is overexpressed in cancer.
  • transgenic animals can be generated that overexpress the cancer protein.
  • promoters of various strengths can be employed to express the fransgene.
  • the number of copies of the integrated fransgene can be determined and compared for a determination of the expression level of the transgene. Animals generated by such methods will find use as animal models of cancer and are additionally useful in screening for modulators to treat cancer. Kits for Use in Diagnostic and/or Prognostic Applications
  • kits are also provided by the invention.
  • such kits may include at' least one of the following: assay reagents, buffers, cancer-specific nucleic acids or antibodies, hybridization probes and/or primers, antisense polynucleotides, ribozymes, dominant negative cancer polypeptides or polynucleotides, small molecule inhibitors of cancer-associated sequences etc.
  • a therapeutic product may include sterile saline or another pharmaceutically acceptable emulsion and suspension base.
  • kits may include instructional materials containing instructions (e.g., protocols) for the practice of the methods of this invention.
  • instructional materials typically comprise written or printed materials, they are not limited to such.
  • a medium capable of storing such instructions and communicating them to an end user is contemplated by this invention.
  • Such media include, but are not limited to, electronic storage media (e.g., magnetic discs, tapes, cartridges, chips), optical media (e.g., CD ROM), and the like.
  • Such media may include addresses to internet sites that provide such instructional materials.
  • kits for screening for modulators of cancer- associated sequences can be prepared from readily available materials and reagents.
  • such kits can comprise one or more of the following materials: a cancer-associated polypeptide or polynucleotide, reaction tubes, and instructions for testing cancer-associated activity.
  • the kit contains biologically active cancer protein.
  • kits and components can be prepared according to the present invention, depending upon the intended user of the kit and the particular needs of the user. Diagnosis would typically involve evaluation of a plurality of genes or products. The genes will typically be selected based on conelations with important parameters in disease which may be identified in historical or outcome data.
  • Table 1 lists medical conditions, abnormalities, or organs affected by disease, referred to in Tables 2A and 3A for which markers have been identified, and other related medical conditions (including va ⁇ ous stages and/or metastases) in which those markers will also be useful, e g , in therapeutic, diagnostic, prognostic, subsetting, vaccine, and other uses blood vessels/angiogenesis hemangiomas, lymphangiomas, a ⁇ giosarcoma, lymphangiosarcoma, Kaposi's sarcoma, wound healing, tissue remodeling, pso ⁇ asis, ischemic, heart disease, inflammatory diseases (e g , arthntis asthma, chronic bronchitis), atherosclerosis, endomel ⁇ osis, presumed ocular histoplasmosis syndrome, hypoxia solid tumors lymphomas, lymphadenitis, lymphangitis, autoimmune diseases (e g , RA, SLE, juvenile chronic arthntis, pigmented villo ⁇ odular syn
  • fibrosis lung fibrosis idiopathic pulmonary fibrosis, hypersensitivity pneumonitis.interstitial pneumonitis, nonspecific idiopathic pneumonitis), chronic obstructive pulmonary disease (e g , emphysema, chronic bronchitis), asthma, bronchiectasis, cirrhosis (liver fibrosis), renal fibrosis, scleroderma, wound healing , head and neck tumors of the nasal cavity, paranasal sinuses, nasopharynx, oral cavity, oral pharynx, lip, larynx, hypopharynx, salivary glands, paragangliomas, esophagus kidney clear cell (nonpapillary) carcinoma papillary carcinoma, chromophobe renal carcinoma, hypernephroma adenocarcinoma, sporadic renal carcinomas,
  • Tables 2B-72B, 76B, and 79B list accession numbers for Pkeys lacking UmgenelD's for Tables 2A-72A, 76A, and 79A, respectively
  • gene cluster number 0 from which oligonucleotides were designed
  • Gene clusters were compiled using sequences denved from Genbank ESTs and mRNAs These sequences were clustered based on sequence simila ⁇ ty using Cluste ⁇ g and Alignment Tools (DoubleTwist, Oakland California)
  • Genbank accession numbers for sequences comp ⁇ sing each cluster are listed in the "Accession" column
  • Tables 2C-72C, 76C, and 79C list genomic positioning for Pkeys lacking Unigene ID's and accession numbers in Tables 2A-72A, 76A, and 79A, respectively
  • genomic sequence source used for prediction Nucleotide locations of each predicted exon are also listed
  • Table 2A provides preferred disease indications and preferred utilities for about 413 selected genes These genes were identified using Eos/Affymet ⁇ x Genechip arrays 0
  • blad bladder diseases
  • angio blood vessel diseases
  • EWS EWS
  • E angio CTL+s m 133370, AF245505 Hs 72157, Adlican, breast, lung, pane, diag 310016, AW449612, Hs 152475, ESTs, colon, GTL 5 322303, AI357412, Hs 157601, ESTs, colon, pros, fibro, breast, CTL+diag
  • hypoxia-mducible protein 2 lung, renal, CTL
  • Hs 42645 solute earner family 16 (mono, breast, pane, uter, mela, mAb+s m 416658, U03272, Hs 79432, fibnllin 2 (congenital contra, lung, ovar, uter, blad, angio, test, sarc, diagra
  • Hs 350470 trefoil factor 1 (breast cance, breast pane, lung o uc, diag 421659, NMJ14459, Hs 106511, protocadhe ⁇ n 17, fibro, mAb 421753, BE314828, Hs 107911, ATP-binding cassette, sub-fami, lung, mAb+s m 421817, AF146074, Hs 108660, ATP-binding cassette, sub-fami, lung, cerv, headnk, blad, mAb+s m 421829, AB018330, Hs 108708, calcium/calmodulin-dependent p, pros, s m 422048, NM_012445, Hs 288126, spondm 2, extracellular mat ⁇ , pane pros sarc, diag
  • Hs 111256 arachidonate 15-l ⁇ poxygenase, , pros, s m 422109, S73265, Hs 1473, gast ⁇ n releasing peptide, pane, lung, colon, fibro, diag 422158, L10343, Hs 112341, protease inhibitor 3, skin der, headnk, blad, lung, cerv, stom, esoph, diag 422192, AA305159, Hs 113019, fls485, mela, s m 422260, AA315993, Hs 105484, regenerating gene type IV, colon, omuc, stom, pane, mAb+diag
  • NM_002205 Hs 149609, integ ⁇ n, alpha 5 (fibronectin, pane, pros.angio, blad, lung, mAb+s m 424620, AA101043, Hs 151254, kallikrein 7 (chymotryptic, st, ovar; diag
  • bone morphogenetic protein 7 (, ovar, colon, blad, lung, cerv, mAb+diag
  • Hs 171014 VGF nerve growth factor induci, mela, sarc, diag 426761, AI015709, Hs 172089, PORIMIN Prc-oncosis receptor i, lung, esoph, pros, uter, pane, colon, ovar, headnk, mAb+s m
  • H55709 Hs 2250
  • leukemia inhibitory factor ch, ovar, pane, leuk, lung, diag 428296, NMJ03058, Hs 183572, solute earner family 22 (orga, renal, mAb+s m
  • Hs 184601 solute earner family 7 (catio, lung, blad, headnk, cerv, esoph, glio, uter, stom, colon, mela, mAb+s m
  • RAIG retinoic acid induced 3
  • Hs 234434 hairy/enhancer-of split relate, glio, s m 430178, AW449612, Hs 152475, 3 UTR of achaete scute comple, colon, stom, ovar; CTL
  • nucleolar protein 3 apoptosis, renal, CTL 432596, AJ224741, Hs 278461, mat ⁇ lin 3, pane, breast, sarc, diag
  • NM_002104 Hs 3066, granzyme K (senne protease, g, renal, breast, lung, stom, hepC, fibro, leuk, CTL
  • Hs 334762 type I transmembrane protein F, pane, colon, lung ovar, renal, esoph, mela blad, stom cerv, mAb 444090, S69115, Hs 10306, natural killer cell group 7 se, fibro, renal, mela, drag 444371, BE540274, Hs 239, forkhead box M1, lung, headnk, blad, glio, test, mela, s m
  • Hs 11383 small inducible cytokine subfa, fibro, esoph, drag 444781, NM_014400, Hs 11950, GPI-anchored metastasis-associ, lung, blad, headnk, cerv, mAb+diag
  • ADAMTS2 a disintegnn like a, headnk, breast colon, leuk, lung, blad, esoph, stom, sarc, mAb+diag
  • Table 3A provides preferred disease indications and preferred utilities for about 2709 selected genes These genes were identified using Eos/Affymetnx Genechip arrays
  • chromosome segregation 1 (yeas, ovar, lung, blad , diag 102348, U37519, Hs 87539, aldehyde dehydrogenase 3 famil, lung, blad, s m
  • trefoil factor 1 (breast cance, breast pane, diag 103021, BE001596, Hs 85266, mteg ⁇ n, beta 4, lung blad, mAb
  • ADAMTS2 a disinteg ⁇ n-like a, breast, colon, leuk, lung, blad, mAb+diag
  • Hs 288969 Hs 288969, HSCARG protein, breast, diag 111900, AF131784, Hs 25318, Homo sapiens clone 25194 mRNA , breast, diag 111929, AF027208, Hs 112360, promimn (mouse)-l ⁇ ke 1, colon, breast, fibro, mAb _ _ 112134, 41823, Hs 7413, ESTs, calsy ⁇ ten ⁇ n-2, breast, EWS, diag 5 112244, AB029000, Hs 70823, KIAA1077 protein, breast colon, blad, lung, diag
  • Hs 104800 hypothetical protein FLJ10134, breast, drag 121748, BE536911, Hs 234545, hypothetical protein NUF2R, breast, drag
  • Hs 18212 DNA segment on chromosome X (u, breast, diag 130760, AW379130, Hs 18953, phosphodiesterase 9A, pros, CTL+s m 130800, AI187292, Hs 19574, hypothetical protein MGC5469, colon, lung, diag 130839, AB011169, Hs 380875, similar to S cerevisiae SSM4, angio, diag 130844, U76248, Hs 20191, seven in absentia (Drasophila), breast, diag
  • Hs 82772 collagen, type XI, alpha 1, breast, lung, ovar, headnk, CTL 134470, X54942, Hs 83758, CDC28 protein kinase 2, lung, blad, headnk, s m 134520, BE091005, Hs 349506, activated RNA polymerase II t ⁇ ovar, s m 134529, AW411479, Hs 848, FK506-b ⁇ nd ⁇ ng protein 4 (59kD), breast, diag 5 134570, U66615, Hs 172280, SWI/SNF related, matrix associ, EWS, CTL+s m

Abstract

Described herein are genes whose expression are up-regulated or down-regulated in specific cancers or other diseases, or are otherwise regulated in disease. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of these selected conditions.

Description

METHODS OF DIAGNOSIS OF CANCER, COMPOSITIONS AND METHODS OF SCREENING FOR MODULATORS OF CANCER CROSS-REFERENCES TO RELATED APPLICATIONS
This application claims priority to USSN 60/340,376, filed December 14, 2001; Attorney Docket Number 018501-006400US, filed February 8, 2002; USSN 60/347,211, filed January 8, 2002; USSN 60/334,393, filed November 29, 2001; USSN 60/335,394, filed November 15, 2001; USSN 60/347,349, filed January 10, 2002; USSN 60/368,809, filed March 29, 2002; USSN 60/409,450, filed September 9, 2002; USSN 60/359,077, filed February 20, 2002; USSN 60/386,614, filed June 5, 2002; USSN 60/356,714, filed February 13, 2002; USSN 60/397,775 filed July 22, 2002; USSN 60/332,464, filed November 21, 2001; USSN 60/397,845, filed July 22, 2002; USSN 60/370,110, filed April 4, 2002; USSN 60/396,839, filed July 16, 2002; USSN 60/350,666, filed November 13, 2001; and USSN 60/372,246, filed April 12, 2002; each of which is incoφorated herein by reference for all praposes. The application also incorporates by reference PCT/US02/29560; PCT/US02/02242; and PCT/US 02/ 17594.
FIELD OF THE INVENTION The invention relates to the identification of nucleic acid and protein expression profiles and nucleic acids, products, and antibodies thereto that are involved in cancer and other diseases; and to the use of such expression profiles and compositions in the diagnosis, prognosis, and therapy of these conditions. The invention further relates to methods for identifying and using agents and/or targets that modulate these conditions.
BACKGROUND OF THE INVENTION Cancer is a major cause of morbidity in the United States. For example, in 1996, the American Cancer Society estimated that 1,359,150 people were diagnosed with a malignant neoplasm and 554,740 died from one of these diseases. Cancer is responsible for 23.9 percent of all American deaths and is exceeded only by heart disease as a cause of mortality (33 percent). Unfortunately, cancer mortality is increasing and sometime early in this century, cancer is expected to become the leading cause of mortality in the United States as it already is in Japan.
Cancers share the charactaristic of disordered control over normal cell division, growth, and differentiation. Their initial clinical manifestations are extremely heterogeneous, with over 70 types of cancer arising in virtually every organ and tissue of the body. Moreover, some of those similarly classified cancer types may represent multiple different molecular diseases. Unfortunately, some cancers may be virtually asymptomatic until late in the disease course, when treatment is more difficult, and prognosis grim. Treatment for cancer typically includes surgery, chemotherapy, and/or radiation therapy.
Although nearly 50 percent of cancer patients can be effectively treated using these methods, the current therapies all induce serious side effects which diminish quality of life. The identification of novel therapeutic targets and diagnostic markers will be important for improving the diagnosis, prognosis, and treatment of cancer patients. Recent advances in molecular medicine have increased the interest in tumor-specific antigens that could serve as targets for various immunotherapeutic or small molecule strategies. Antigens suitable for immunotherapeutic strategies should be highly expressed in cancer tissues, preferably accessible from the vasculature and at the cell surface, and ideally not expressed in normal adult tissues. Expression in tissues that are dispensable for life, however, may be tolerated, e.g., reproductive organs, especially those absent in one sex. Examples of antigens that are currently available for the detection and treatment of certain cancers include Her2/neu and the B-cell antigen CD20. Humanized monclonal antibodies directed to Her2/neu (Herceptin®/trastuzumab) are currently in use for the treatment of metastatic breast cancer. See Ross and Fletcher (1998) Stem Cells 16:413-428. Similarly, anti-CD20 monoclonal antibodies (Rituxin®/rituximab) are used to effectively treat non-Hodgkin's lymphoma. See Maloney, et al. (1997) Blood 90:2188-2195; Leget and Czuczman (1998) Curr. Opin. Oncol. 10:548-551.
The elucidation of a role for novel proteins and compounds in disease states for identification of therapeutic targets and diagnostic markers is valuable for improving the current treatment of cancer patients. Accordingly, provided herein are molecular targets for therapeutic intervention in various defined cancers. Additionally, provided herein are methods that can be used in diagnosis and prognosis of cancer. Further provided are methods that can be used to screen candidate bioactive agents for the ability to modulate cancer.
SUMMARY OF THE INVENTION The present invention provides methods for determining the presence or absence of a pathological cell in a patient, the method comprising detecting a nucleic acid comprising a sequence at least 80% identical to a sequence as described in Tables 2A-80 in a biological sample from the patient, thereby determining the presence or absence of the pathological cell. In certain embodiments of the method, the pathology is described in Table 1, including a cancer; the biological sample comprises isolated nucleic acids; the nucleic acids are mRNA; the biological sample is tissue from an organ which is affected by the pathology of Table 1, including a cancer; a further step is used of amplifying nucleic acids before the step of detecting the nucleic acid; the detecting is of a protein encoded by the nucleic acid; the nucleic acid comprises a sequence as described in Tables 2A-80; the detecting step is carried out by using a labeled nucleic acid probe, utilizing a biochip comprising at sequence at least 80% identical to a sequence as described in Tables 2A-80, or detecting a polypeptide encoded by the nucleic acid; or the patient is undergoing a therapeutic regimen to treat the pathology of Table 1, or is suspected of having the pathology or cancer.
Compositions are also provided, e.g., an isolated nucleic acid molecule comprising a sequence as described in Tables 2A-80, including, e.g., those which are labeled; an expression vector comprising such nucleic acid; a host cell comprising such expression vector; an isolated polypeptide which is encoded by such a nucleic acid molecule comprising a sequence as described in Tables 2A-80; or an antibody that specifically binds the polypeptide. In particular embodiments, the antibody is: conjugated to an effector component, is conjugated to a detectable label (including, e.g., a fluorescent label, a radioisotope, or a cytotoxic chemical), an antibody fragment, or is a humanized antibody.
Additional methods are provided, including methods for specifically targeting a compound to a pathological cell in a patient, the method comprising administering to the patient an antibody, as described, thereby providing the targetting. Others include, e.g., methods for determining the presence or absence of a pathological cell in a patient, the methods comprising contacting a biological sample with an antibody, as described. In more particular methods, the antibody is: conjugated to an effector component, or to a fluorescent label; or the biological sample is a blood, serum, urine, or stool sample.
Further methods include those for identifying a compound that modulates a pathology- associated polypeptide, the method comprising steps of: contacting the compound with a pathology-associated polypeptide, the polypeptide encoded by a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as described in Tables 2A-80; and determining the functional effect of the compound upon the polypeptide. Another drug screening assay method comprises steps of: administering a test compound to a mammal having a pathology of Table 1 or a cell isolated therefrom; and comparing the level of gene expression of a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as described in Tables 2A-80 in a treated cell or mammal with the level of gene expression of the polynucleotide in a control cell or mammal, wherein a test compound that modulates the level of expression of the polynucleotide is a candidate for the treatment of the pathology. DETAILED DESCRIPTION OF THE INVENTION
In accordance with the objects outlined above, the present invention provides novel methods for diagnosis and prognosis evaluation for various disorders, e.g., angiogenesis, fibrosis, and various defined forms of cancer, including metastatic cancer, as well as methods for screening for compositions which modulate such conditions. Also provided are methods for treating such disorders or cancers. See, e.g., American Society of Clinical Oncology (ed. 2001) ASCO Curriculum: Symptom Management Kendall/Hunt, ISBN: 0787277851; Bonadonna, et al. (2001) Textbook of Breast Cancer (2d ed.) Dunitz Martin, ISBN: 1853178241; Devita and Hellman (eds. 2001) Cancer Principles and Practice of Oncology (2 vols.), Lippincott Williams, ISBN: 0781723876; Howell, et al. (2001) Breast Cancer Isis Medical Media, ISBN: 1901865584; Kaye and Laws (2001) Brain Tumours: An Encyclopedic Approach (2d ed.)
Churchill Livingstone, ISBN: 0443064261; Mihm, et al. (2001) The Melanocvtic Proliferation: A Comprehensive Textbook of Pigmented Lesions Wilev-Liss. ISBN: 0471252719; Montgomery and Aaron (2001) Clinical Pathology of Soft-Tissue Tumors Marcel Dekker, ISBN: 0824702905; Petrovich, et al. (eds. 2001) Combined Modality of Central Nervous System Tumors (Medical Radiology) Springer Verlag, ISBN: 3540660534; Rosen (2001) Rosen's Breast Pathology Lippincott Williams and Wilkins, ISBN: 0781723795; Shah, et al. (2001) Oral Cancer Isis Medical Media, ISBN: 189906687X; Weiss and Goldblum (2001) Enzinger and Weiss's Soft Tissue Tumors (4th ed.) Mosby, ISBN: 0323012000; Abeloff, et al. (eds. 2000) Clinical Oncology (2d ed.) Churchill Livingstone, ISBN: 044307545X; American Society of Clinical Oncology (ed. 2000) Cancer Genetics and Cancer Predisposition Testing Kendall Hunt, ISBN: 0787276154; Fletcher (2000) Diagnostic Histopathology of Tumors (2 vols. 2d ed.) Churchill Livingstone, ISBN: 0443079927; Vogelzang (ed. 2000) Comprehensive Textbook of Genitourinary Oncology (2d ed.) Lippincott Williams and Wilkins, ISBN: 0683306456; Holland, et al. (eds. 2000) Holland-Frei Cancer Medicine (Book with CD-ROM 5th ed.) Decker, ISBN: 1550091131; Turrisi, et al. (2000) Lung Cancer Isis Medical Media, ISBN: 1901865428; Bartolozzi and Lencioni (eds. 1999) Liver Malignancies: Diagnostic and Interventional Radiolo y (Medical Radiology) Springer Verlag, ISBN: 3540647562; Gasparini (ed. 1999) Prognostic Variables in Node-Negative and Node-Positive Breast Cancer Kluwer, ISBN: 0792384474; Hansen (ed. 1999) The LASLC Textbook of Lung Cancer: International Association for the Study of Lung Cancer Dunitz Martin, ISBN: 1853177083; Raghavan, et al. (eds. 1999) Textbook of Uncommon Cancer (2nd ed.) Wiley, ISBN: 0471929212; Thawley, et al. (eds. 1999) Comprehensive Management of Head and Neck Tumors (2 vols.) Saunders, ISBN: 0721655823; Whittaker and Holmes (eds. 1999) Leukemia and Related Disorders (3d ed.) Blackwell Science, ISBN: 0865426074; Aapro (ed. 1998) OncoMedia: Medical Oncology (CD-ROM) Elsevier Science, ISBN: 0080427480; Abeloff (1998) Clinical Oncology (Library Version 2 CD-ROM Individual Version 2.0 Windows and Macintosh) Harcourt Brace, ISBN: 0443075557; Benson (ed. 1998) Gastrointestinal Oncology (Cancer Treatment and Research, CTAR 98) Kluwer, ISBN: 0792382056; Brambilla and Brambilla (eds. 1998) Lung Tumors: Fundamental Biology and Clinical Management (Vol 124) Marcel Dekker, ISBN: 0824701607; Canellos, et al. (eds. 1998) The Lymphomas Saunders, ISBN: 0721650309; Greenspan and Remagen (1998) Differential Diagnosis of Tumors and Tumor-Like Lesions of Bones and Joints Lippincott Williams and Wilkins Publishers, ISBN: 0397517106; Hiddemann (ed. 1998) Acute Leukemias VII: Experimental Approaches and Novel Therapies (Haematologie Und Bluttransfusion, Vol 39), Springer Verlag, ISBN: 3540635041; Husband and Reznek (1998) Imaging in Oncology (2 vols.) Mosby, ISBN: 1899066489; Leibel and Phillips (eds. 1998) Textbook of Radiation Oncology Saunders, ISBN: 0721653367; Maloney and Miller (eds. 1998) Cutaneous Oncology: Pathophysiology, Diagnosis, and Management Blackwell Science, ISBN: 0865425175; Mittal, et al. (eds. 1998) Advances in Radiation Therapy Kluwe, ISBN: 0792399811; Oldham (ed. 1998) Principles of Cancer Biotherapy (3d ed.) Kluwer, ISBN: 0792335074; Ozols (ed. 1998 Gynecologic Oncology Kluwer. ISBN: 0792380703; Parkin, et al. (eds. 1998) Cancer Incidence in Five Continents (Iarc Scientific Publications, No 143) Oxford University Press, ISBN: 9283221435; Perez and Brady (eds. 1998) Principles and
Practice of Radiation Oncology Lippincott Williams and Wilkins, ISBN: 0397584164; Black, et al. (eds. 1997 Cancer of the Nervous System Blackwell Science, ISBN: 0865423849; Bonadonna, et al. (1997) Textbook of Breast Cancer: A Clinical Guide to Therapy Blackwell Science, ISBN: 1853173487; Pollock (ed. 1997) Surgical Oncology Kluwer, ISBN: 0792399005; Sheaves, et al. (eds. 1997) Clinical Endocrine Oncology Blackwell Science,
ISBN: 086542862X; Vahrson (1997) Radiation Oncology of Gynecological Cancers Springer Verlag, ISBN: 0387567682; Walterhouse and Cohn (eds. 1997 Diagnostic and Therapeutic Advances in Pediatric Oncology Kluwer, ISBN: 0792399781; Aisner (ed. 1996) Comprehensive Textbook of Thoracic Oncology Lippincott, Williams and Wilkins, ISBN: 0683000624; Bertino, et al. (eds. 1996) Encyclopedia of Cancer (3 vols.) Academic, ISBN: 012093230X; Cavalli, et al. (1996) Textbook of Medical Oncology Dunitz Martin, ISBN: 1853172901; Peckham, et al. (eds. 1995) Oxford Textbook of Oncology (2-Vols.) Oxford University Press, ISBN: 0192616854; and Freireich and Kantarjian (eds. 1996) Molecular Genetics and Therapy of Leukemia (Cancer Treatment and Research, V. 84) Kluwer, ISBN: 0792339126.
In particular, identification of markers selectively expressed on defined cancers allows for use of that expression in diagnostic, prognostic, or therapeutic methods. As such, the invention defines various compositions, e.g., nucleic acids, polypeptides, antibodies, and small molecule agonists/antagonists, which will be useful to selectively identify those markers. For example, therapeutic methods may take the form of protein therapeutics which use the marker expression for selective localization or modulation of function (for those markers which have a causative disease effect), for vaccines, identification of binding partners, or antagonism, e.g., using antisense or RNAi. The markers may be useful for molecular characterization of subsets of the diseases, e.g., as provided in Table 1, which subsets may actually require very different treatments. Moreover, the markers may also be important in related diseases to the specific disorders and cancers, e.g., which affect similar tissues in non-malignant diseases, or have similar mechanisms of induction/maintenance. Metastatic processes or characteristics may also be targeted. Diagnostic and prognostic uses are made available, e.g., to subset related but distinct diseases, or to determine treatment strategy. The detection methods may be based upon nucleic acid, e.g., PCR or hybridization techniques, or protein, e.g., ELISA, imaging, JJHC, etc. The diagnosis may be qualitative or quantitative, and may detect increases or decreases in expression levels. Tables 2B-76B provide unigene cluster identification numbers for the nucleotide sequence of genes that exhibit increased or decreased expression in diseased samples (see Tables 1-3), particularly sequences involved in angiogenesis, arthritis, prostate cancer, breast cancer, colorectal cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, ovarian cancer, pancreatic cancer, renal cancer, stomach cancer, skin cancer, testicular cancer, uterine cancer, glioblastoma, Ewing sarcoma, soft tissue sarcoma, and lung fibrosis. Tables 2A-80 also provide an exemplar accession number that provides a nucleotide sequence that is part of the unigene cluster. Definitions
The term "cancer protein" or "cancer polynucleotide" or "cancer-associated transcript" refers to nucleic acid and polypeptide polymoφhic variants, alleles, mutants, and interspecies homologues that: (1) have a nucleotide sequence that has greater than about 60% nucleotide sequence identity, 65%, 70%, 75%, 80%, 85%, 90%, preferably about 92%, 94%, 96%, 97%, 98%, or 99% or greater nucleotide sequence identity, preferably over a region of over a region of at least about 25, 50, 100, 200, 500, 1000, or more nucleotides, to a nucleotide sequence of or associated with a gene of Tables 1-80; (2) bind to antibodies, e.g., polyclonal antibodies, raised against an immunogen comprising an amino acid sequence encoded by a nucleotide sequence of or associated with a gene of Tables 1-80, and conservatively modified variants thereof; (3) specifically hybridize under stringent hybridization conditions to a nucleic acid sequence, or the complement thereof of Tables 1-80 and conservatively modified variants thereof; or (4) have an amino acid sequence that has greater than about 60% amino acid sequence identity, 65%, 70%, 75%, 80%, 85%, preferably 90%, 91%, 93%, 95%, 97%, 98%, or 99% or greater amino sequence identity, preferably over a region of over a region of at least about 25, 50, 100, 200, 500, 1000, or more amino acids, to an amino acid sequence encoded by a nucleotide sequence of or associated with a gene of Tables 1-80. A polynucleotide or polypeptide sequence is typically from a mammal including, but not limited to, primate, e.g., human; rodent, e.g., rat, mouse, hamster; cow, pig, horse, sheep, or other mammal. A "cancer polypeptide" and a "cancer polynucleotide," include both naturally occurring or recombinant forms.
A "full length" cancer protein or nucleic acid refers to a cancer polypeptide or polynucleotide sequence, or a variant thereof, that contains elements normally contained in one or more naturally occurring, wild type cancer polynucleotide or polypeptide sequences. The "full length" may be prior to, or after, various stages of post-translational processing or splicing, including alternative splicing.
"Biological sample" as used herein is a sample of biological tissue or fluid that contains nucleic acids or polypeptides, e.g., of a cancer protein, polynucleotide, or transcript. Such samples include, but are not limited to, tissue isolated from primates, e.g., humans, or rodents, e.g., mice, and rats. Biological samples may also include sections of tissues such as biopsy and autopsy samples, frozen sections taken for histologic puφoses, archival samples, blood, plasma, serum, sputum, stool, tears, mucus, hair, skin, etc. Biological samples also include explants and primary and/or transformed cell cultures derived from patient tissues. A biological sample is typically obtained from a eukaryotic organism, most preferably a mammal such as a primate, e.g., chimpanzee or human; cow; dog; cat; a rodent, e.g., guinea pig, rat, mouse; rabbit; or a bird; reptile; or fish. Livestock and domestic animals are of interest.
"Providing a biological sample" means to obtain a biological sample for use in methods described in this invention. Most often, this will be done by removing a sample of cells from an animal, but can also be accomplished by using previously isolated cells (e.g., isolated by another person, at another time, and/or for another puφose), or by performing the methods of the invention in vivo. Archival tissues or materials, having treatment or outcome history, will be particularly useful. The terms "identical" or percent "identity," in the context of two or more nucleic acids or polypeptide sequences, refer to two or more sequences or subsequences that are the same or have a specified percentage of amino acid residues or nucleotides that are the same (e.g., about 70% identity, preferably 75%, 80%, 85%, 90%, 91%, 93%, 95%, 97%, 98%, 99%, or higher identity over a specified region, when compared and aligned for maximum correspondence over a comparison window or designated region) as measured using, e.g., a BLAST or BLAST 2.0 sequence comparison algorithms with default parameters described below, or by manual alignment and visual inspection (see, e.g., NCBI web site http://www.ncbi.nlm.nih.gov/BLAST/ or the like). Such sequences are then said to be "substantially identical." This definition also refers to, or may be applied to, the complement of a test sequence. The definition also includes sequences that have deletions and/or insertions, substitutions, and naturally occurring, e.g., polymoφhic or allelic variants, and man-made variants. As described below, the preferred algorithms can account for gaps and the like. Preferably, identity exists over a region that is at least about 25 amino acids or nucleotides in length, or more preferably over a region that is about 50-100 amino acids or nucleotides in length. For sequence comparison, typically one sequence acts as a reference sequence, to which test sequences are compared. When using a sequence comparison algorithm, test and reference sequences are entered into a computer, subsequence coordinates are designated, if necessary, and sequence algorithm program parameters are designated. Preferably, default program parameters can be used, or alternative parameters can be designated. The sequence comparison algorithm then calculates the percent sequence identities for the test sequences relative to the reference sequence, based on the program parameters. A "comparison window", as used herein, includes reference to a segment of contiguous positions selected from the group consisting typically of from about 20 to 600, usually about 50 to 200, more usually about 100 to 150, in which a sequence may be compared to a reference sequence of the same number of contiguous positions after the two sequences are optimally aligned. Methods of alignment of sequences for comparison are well-known. Optimal alignment of sequences for comparison can be conducted, e.g., by the local homology algorithm of Smith and Waterman (1981) Adv. Appl. Math. 2:482-489, by the homology alignment algorithm of Needleman and Wunsch (1970) J. Mol. Biol. 48:443-453, by the search for similarity method of Pearson and Lipman (1988) Proc. Nat'l. Acad. Sci. USA 85:2444-2448, by computerized implementations of these algorithms (GAP, BESTFIT, FASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group, 575 Science Dr., Madison, WI), or by manual alignment and visual inspection (see, e.g., Ausubel, et al. (eds. 1995 and supplements) Current Protocols in Molecular Biology Wiley).
Preferred examples of algorithms that are suitable for determining percent sequence identity and sequence similarity include the BLAST and BLAST 2.0 algorithms, which are described in Altschul, et al. (1977) Nuc. Acids Res. 25:3389-3402 and Altschul, et al. (1990) Mol. Biol. 215:403-410. BLAST and BLAST 2.0 are used, with the parameters described herein, to determine percent sequence identity for the nucleic acids and proteins of the invention. Software for performing BLAST analyses is publicly available through the National Center for Biotechnology Information (http://www.ncbi.nlm.nih.gov/). This algorithm involves first identifying high scoring sequence pairs (HSPs) by identifying short words of length W in the query sequence, which either match or satisfy some positive-valued threshold score T when aligned with a word of the same length in a database sequence. T is referred to as the neighborhood word score threshold (Altschul, et al., supra). These initial neighborhood word hits act as seeds for initiating searches to find longer HSPs containing them. The word hits are extended in both directions along each sequence for as far as the cumulative alignment score can be increased. Cumulative scores are calculated using, e.g., for nucleotide sequences, the parameters M (reward score for a pair of matching residues; always > 0) and N (penalty score for mismatching residues; always < 0). For amino acid sequences, a scoring matrix is used to calculate the cumulative score. Extension of the word hits in each direction are halted when: the cumulative alignment score falls off by the quantity X from its maximum achieved value; the cumulative score goes to zero or below, due to the accumulation of one or more negative- scoring residue alignments; or the end of either sequence is reached. The BLAST algorithm parameters W, T, and X determine the sensitivity and speed of the alignment. The BLASTN program (for nucleotide sequences) uses as defaults a wordlength (W) of 11, an expectation (E) of 10, M=5, N=-4 and a comparison of both strands. For amino acid sequences, the BLASTP program uses as defaults a wordlength of 3, and expectation (E) of 10, and the BLOSUM62 scoring matrix (see Henikoff and Henikoff (1992) Proc. Natl. Acad. Sci. USA 89:10915-919) alignments (B) of 50, expectation (E) of 10, M=5, N=-4, and a comparison of both strands.
The BLAST algorithm also performs a statistical analysis of the similarity between two sequences. See, e.g., Karlin and Altschul (1993) Proc. Nat'l. Acad. Sci. USA 90:5873-5787. One measure of similarity provided by the BLAST algorithm is the smallest sum probability (P(N)), which provides an indication of the probability by which a match between two nucleotide or amino acid sequences would occur by chance. For example, a nucleic acid is considered similar to a reference sequence if the smallest sum probability in a comparison of the test nucleic acid to the reference nucleic acid is less than about 0.2, more preferably less than about 0.01, and most preferably less than about 0.001. Log values may be negative large numbers, e.g., 5, 10, 20, 30, 40, 40, 70, 90, 110, 150, 170, etc.
An indication that two nucleic acid sequences are substantially identical is that the polypeptide encoded by the first nucleic acid is immunologically cross reactive with the antibodies raised against the polypeptide encoded by the second nucleic acid. Thus, a polypeptide is typically substantially identical to a second polypeptide, e.g., where the two peptides differ only by conservative substitutions. Another indication that two nucleic acid sequences are substantially identical is that the two molecules or their complements hybridize to each other under stringent conditions. Yet another indication that two nucleic acid sequences are substantially identical is that the same primers can be used to amplify the sequences. A "host cell" is a naturally occurring cell or a transformed cell that contains an expression vector and supports the replication or expression of the expression vector. Host cells may be cultured cells, explants, cells in vivo, and the like. Host cells may be prokaryotic cells such as E. coli, or eukaryotic cells such as yeast, insect, amphibian, or mammalian cells such as CHO, HeLa, and the like (see, e.g., the American Type Culture Collection catalog or web site, www.atcc.org).
The terms "isolated," "purified," or "biologically pure" refer to material that is substantially or essentially free from components that normally accompany it as found in its native state. Purity and homogeneity are typically determined using analytical chemistry techniques such as polyacrylamide gel electrophoresis or high performance liquid chromatography. A protein or nucleic acid that is the predominant species present in a preparation is substantially purified. In particular, an isolated nucleic acid is separated from some open reading frames that naturally flank the gene and encode proteins other than protein encoded by the gene. The term "purified" in some embodiments denotes that a nucleic acid or protein gives rise to essentially one band in an electrophoretic gel. Preferably, it means that the nucleic acid or protein is at least about 85% pure, more preferably at least 95% pure, and most preferably at least 99% pure. "Purify" or "purification" in other embodiments means removing at least one contaminant or component from the composition to be purified. In this sense, purification does not require that the purified compound be homogeneous, e.g., 100% pure. The terms "polypeptide," "peptide," and "protein" are used interchangeably herein to refer to a polymer of amino acid residues. The terms apply to amino acid polymers in which one or more amino acid residue is an artificial chemical mimetic of a corresponding naturally occurring amino acid, as well as to naturally occurring amino acid polymers, those containing modified residues, and non-naturally occurring amino acid polymers.
The term "amino acid" refers to naturally occurring and synthetic amino acids, as well as amino acid analogs and amino acid mimetics that function similarly to the naturally occurring amino acids. Naturally occurring amino acids are those encoded by the genetic code, as well as those amino acids that are later modified, e.g., hydroxyproline, γ-carboxyglutamate, and O- phosphoserine. Amino acid analogs refers to compounds that have the same basic chemical structure as a naturally occurring amino acid, e.g., an carbon that is bound to a hydrogen, a carboxyl group, an amino group, and an R group, e.g., homoserine, norleucine, methionine sulfoxide, methionine methyl sulfonium. Such analogs may have modified R groups (e.g., norleucine) or modified peptide backbones, but retain somebasic chemical structure as a naturally occurring amino acid. Amino acid mimetic refers to a chemical compound that has a structure that is different from the general chemical structure of an amino acid, but that functions similarly to another amino acid.
Amino acids may be referred to herein by either their commonly known three letter symbols or by the one-letter symbols recommended by the IUPAC-IUB Biochemical
Nomenclature Commission. Nucleotides, likewise, may be referred to by their commonly accepted single-letter codes. "Conservatively modified variant" applies to both amino acid and nucleic acid sequences. With respect to particular nucleic acid sequences, conservatively modified variants refers to those nucleic acids which encode identical or essentially identical amino acid sequences, or where the nucleic acid does not encode an amino acid sequence, to essentially identical or associated, e.g., naturally contiguous, sequences. Because of the degeneracy of the genetic code, a large number of functionally identical nucleic acids encode most proteins. For instance, the codons GCA, GCC, GCG, and GCU each encode the amino acid alanine. Thus, at each position where an alanine is specified by a codon, the codon can be altered to another of the corresponding codons described without altering the encoded polypeptide. Such nucleic acid variations are "silent variations," which are one species of conservatively modified variations. Every nucleic acid sequence herein which encodes a polypeptide also describes silent variations of the nucleic acid. In certain contexts each codon in a nucleic acid (except AUG, which is ordinarily the only codon for methionine, and TGG, which is ordinarily the only codon for tryptophan) can be modified to yield a functionally similar molecule. Accordingly, a silent variation of a nucleic acid which encodes a polypeptide is implicit in a described sequence with respect to the expression product, but not necessarily with respect to actual probe sequences.
As to amino acid sequences, one of skill will recognize that individual substitutions, deletions, or additions to a nucleic acid, peptide, polypeptide, or protein sequence which alters, adds, or deletes a single amino acid or a small percentage of amino acids in the encoded sequence is a "conservatively modified variant" where the alteration results in the substitution of an amino acid with a chemically similar amino acid. Conservative substitution tables providing functionally similar amino acids are well known. Such conservatively modified variants are in addition to and do not exclude polymoφhic variants, interspecies homologs, and alleles of the invention. Typically conservative substitutions include for one another: 1) Alanine (A), Glycine (G); 2) Aspartic acid (D), Glutamic acid (E); 3) Asparagine (N), Glutamine (Q); 4) Arginine (R), Lysine (K); 5) Isoleucine (I), Leucine (L), Methionine (M), Valine (V); 6) Phenylalanine (F), Tyrosine (Y), Tryptophan (W); 7) Serine (S), Threonine (T); and 8) Cysteine (C), Methionine (M) (see, e.g., Creighton (1984) Proteins: Structure and Molecular Properties Freeman).
Macromolecular structures such as polypeptide structures can be described in terms of various levels of organization. For a general discussion of this organization, see, e.g., Alberts, ( et al. (eds. 2001) Molecular Biology of the Cell (4th ed.) Garland; and Cantor and Schimmel
(1980) Biophysical Chemistry Part I: The Conformation of Biological Macromolecules
Freeman. "Primary structure" refers to the amino acid sequence of a particular peptide.
"Secondary structure" refers to locally ordered, three dimensional structures within a polypeptide. These structures are commonly known as domains. Domains are portions of a polypeptide that often form a compact unit of the polypeptide and are typically 25 to approximately 500 amino acids long. Typical domains are made up of sections of lesser organization such as stretches of β-sheet and α-helices. "Tertiary structure" refers to the complete three dimensional structure of a polypeptide monomer. "Quaternary structure" refers to the three dimensional structure formed, usually by the noncovalent association of independent tertiary units. Anisotropic terms are also known as energy terms.
"Nucleic acid" or "oligonucleotide" or "polynucleotide" or grammatical equivalents used herein means at least two nucleotides covalently linked together. Oligonucleotides are typically from about 5, 6, 7, 8, 9, 10, 12, 15, 25, 30, 40, 50, or more nucleotides in length, up to about 100 nucleotides in length. Nucleic acids and polynucleotides are a polymers of any length, including longer lengths, e.g., 200, 300, 500, 1000, 2000, 3000, 5000, 7000, 10,000, etc. A nucleic acid of the present invention will generally contain phosphodiester bonds, although in some cases, nucleic acid analogs are included that may have at least one different linkahge, e.g., phosphoramidate, phosphorothioate, phosphorodithioate, or O-methylphophoroamidite linkages (see Eckstein (1992) Oligonucleotides and Analogues: A Practical Approach Oxford Univ. Press); and peptide nucleic acid backbones and linkages. Other analog nucleic acids include those with positive backbones; non-ionic backbones, and non-ribose backbones, including those described in U.S. Patent Nos. 5,235,033 and 5,034,506, and Chapters 6 and 7 of Sanghvi and Cook (eds. 1994) Carbohydrate Modifications in Antisense Research ACS Symposium Series 580. Nucleic acids containing one or more carbocyclic sugars are also included within one definition of nucleic acids. Modifications of the ribose-phosphate backbone may be done for a variety of reasons, e.g., to increase the stability and half-life of such molecules in physiological environments or as probes on a biochip. Mixtures of naturally occurring nucleic acids and analogs can be made; alternatively, mixtures of different nucleic acid analogs, and mixtures of naturally occurring nucleic acids and analogs may be made.
A variety of references disclose such nucleic acid analogs, including, e.g., phosphoramidate (Beaucage, et al. (1993) Tetrahedron 49:1925-1963 and references therein; Letsinger (1970) J. Org. Chem. 35:3800-3803; Sprinzl, et al. (1977) Eur. J. Biochem. 81:579- 589; Letsinger, et al. (1986) Nucl. Acids Res. 14:3487-499; Sawai, et al. (1984) Chem. Lett. 805, Letsinger, et al. (1988) J. Am. Chem. Soc. 110:4470-4471; and Pauwels, et al. (1986) Chemica Scripta 26:141-149), phosphorothioate (Mag, et al. (1991) Nucleic Acids Res. 19:1437-441; and U.S. Patent No. 5,644,048), phosphorodithioate (Brill, et al. (1989) J. Am. Chem. Soc. 111:2321-2322), O-methylphophoroamidite linkages (see Eckstein (1992) Oligonucleotides and Analogues: A Practical Approach, Oxford Univ. Press), and peptide nucleic acid backbones and linkages (see Egholm (1992) J. Am. Chem. Soc. 114:1895-1897; Meier, et al. (1992) Chem. Int. Ed. Engl. 31:1008-1010; Nielsen (1993) Nature 365:566-568; Carlsson, et al. (1996) Nature 380:207, all of which are incoφorated by reference). Other analog nucleic acids include those with positive backbones (Denpcy, et al. (1995) Proc. Natl. Acad. Sci. USA 92:6097-101; non-ionic backbones (U.S. Patent Nos. 5,386,023, 5,637,684, 5,602,240, 5,216,141, and 4,469,863; Kiedrowski, et al. (1991) Angew. Chem. Intl. Ed. English 30:423-426; Letsinger, et al. (1988) J. Am. Chem. Soc. 110:4470-4471; Letsinger, et al. (1994) Nucleoside and Nucleotide 13: 1597; Chapters 2 and 3 in Sanghvi and Cook (eds. 1994)
Carbohydrate Modifications in Antisense Research ACS Symposium Series 580; Mesmaeker, et al. (1994) Bioorganic and Medicinal Chem. Lett. 4:395-398; Jeffs, et al. (1994) J. Biomolecular NMR 34:17; Horn, et al. (1996) Tetrahedron Lett. 37:743) and non-ribose backbones, including those described in U.S. Patent Nos. 5,235,033 and 5,034,506, and Chapters 6 and 7 in Sanghvi and Cook (eds. 1994) Carbohydrate Modifications in Antisense Research ACS Symposium Series 580. Nucleic acids containing one or more carbocyclic sugars are also included within one definition of nucleic acids (see Jenkins, et al. (1995) Chem. Soc. Rev, pp 169-176). Several nucleic acid analogs are described in Rawls (page 35, June 2, 1997) C&E News.
Particularly preferred are peptide nucleic acids (PNA) which includes peptide nucleic acid analogs. These backbones are substantially non-ionic under neutral conditions, in contrast to the highly charged phosphodiester backbone of naturally occurring nucleic acids. This results in at least two advantages. The PNA backbone exhibits improved hybridization kinetics. PNAs have larger changes in the melting temperature (Tm) for mismatched versus perfectly matched basepairs. DNA and RNA typically exhibit a 2-4° C drop in Tm for an internal mismatch. With the non-ionic PNA backbone, the drop is closer to 7-9° C. Similarly, due to their non-ionic nature, hybridization of the bases attached to these backbones is relatively insensitive to salt concentration. In addition, PNAs are not degraded by cellular enzymes, and thus can be more stable.
The nucleic acids may be single stranded or double stranded, as specified, or contain portions of both double stranded or single stranded sequence. The depiction of a single strand also defines the sequence of the complementary strand; thus the sequences described herein also provide the complement of the sequence. The nucleic acid may be DNA, both genomic and cDNA, RNA, or a hybrid, where the nucleic acid may contain combinations of deoxyribo- and ribo-nucleotides, and combinations of bases, including uracil, adenine, thymine, cytosine, guanine, inosine, xanthine hypoxanthine, isocytosine, isoguanine, etc. "Transcript" typically refers to a naturally occurring RNA, e.g., a pre-mRNA, hnRNA, or mRNA. As used herein, the term "nucleoside" includes nucleotides and nucleoside and nucleotide analogs, and modified nucleosides such as amino modified nucleosides. In addition, "nucleoside" includes non- naturally occurring analog structures. Thus, e.g., the individual units of a peptide nucleic acid, each containing a base, are referred to herein as a nucleoside. A "label" or a "detectable moiety" is a composition detectable by spectroscopic, photochemical, biochemical, immunochemical, physiological, chemical, or other physical means. In general, labels fall into three classes: a) isotopic labels, which may be radioactive or heavy isotopes; b) immune labels, which may be antibodies, antigens, or epitope tags; and c) colored or fluorescent dyes. The labels may be incoφorated into the cancer nucleic acids, proteins, and antibodies. For example, the label should be capable of producing, either directly or indirectly, a detectable signal. The detectable moiety may be a radioisotope, such as ^H, 14c, 32ps 35§5 or 125j5 electron-dense reagents, a fluorescent or chemiluminescent compound, such as fluorescein isothiocyanate, rhodamine, or luciferin, or an enzyme (e.g., as commonly used in an ELISA), biotin, digoxigenin, or haptens and proteins or other entities which can be made detectable such as alkaline phosphatase, beta-galactosidase, or horseradish peroxidase. Methods are known for conjugating the antibody to the label. See, e.g., Hunter, et al. (1962) Nature 144:945; David, et al. (1974) Biochemistry 13:1014-1021; Pain, et al. (1981) Immunol. Meth. 40:219-230; andNygren (1982) J. Histochem. and Cvtochem. 30:407-412.
An "effector" or "effector moiety" or "effector component" is a molecule that is bound (or linked, or conjugated), either covalently, through a linker or a chemical bond, or noncovalently, through ionic, van der Waals, electrostatic, or hydrogen bonds, to an antibody. The "effector" can be a variety of molecules including, e.g., detection moieties including radioactive compounds, fluorescent compounds, enzymes or substrates, tags such as epitope tags, toxins; activatable moieties, chemotherapeutic agents; lipases; antibiotics; chemoattracting moieties, immune modulators (micA/B), or radioisotopes, e.g., emitting "hard" beta, radiation. A "labeled nucleic acid probe or oligonucleotide" is one that is bound, e.g., covalently, through a linker or a chemical bond, or noncovalently, through ionic, van der Waals, electrostatic, or hydrogen bonds to a label such that the presence of the probe may be detected by detecting the presence of the label bound to the probe. Alternatively, methods using high affinity interactions may achieve the same results where one of a pair of binding partners binds to the other, e.g., biotin, streptavidin. As used herein a "nucleic acid probe or oligonucleotide" is a nucleic acid capable of binding to a target nucleic acid of complementary sequence through one or more types of chemical bonds, usually through complementary base pairing, e.g., through hydrogen bond formation. As used herein, a probe may include natural (e.g., A, G, C, or T) or modified bases (7-deazaguanosine, inosine, etc.). In addition, the bases in a probe may be joined by a linkage other than a phosphodiester bond, preferably one that does not functionally interfere with hybridization. Thus, e.g., probes may be peptide nucleic acids in which the constituent bases are joined by peptide bonds rather than phosphodiester linkages. Probes may bind target sequences lacking complete complementarity with the probe sequence depending upon the stringency of the hybridization conditions. The probes are preferably directly labeled, e.g., with isotopes, chromophores, lumiphores, chromogens, or indirectly labeled, e.g., with biotin to which a streptavidin complex may later bind. By assaying for the presence or absence of the probe, one can detect the presence or absence of the select sequence or subsequence. Diagnosis or prognosis may be based at the genomic level, or at the level of RNA or protein expression. The term "recombinant" when used with reference, e.g., to a cell, or nucleic acid, protein, or vector, indicates that the cell, nucleic acid, protein, or vector, has been modified by the introduction of a heterologous nucleic acid or protein or the alteration of a native nucleic acid or protein, or that the cell is derived from a cell so modified. Thus, e.g., recombinant cells express genes that are not found within the native (non-recombinant) form of the cell or express native genes that are otherwise abnormally expressed, under expressed, or not expressed at all. By the term "recombinant nucleic acid" herein is meant nucleic acid, originally formed in vitro, in general, by the manipulation of nucleic acid, e.g., using polymerases and endonucleases, in a form not normally found in nature. In this manner, operably linkage of different sequences is achieved. Thus an isolated nucleic acid, in a linear form, or an expression vector formed in vitro by ligating DNA molecules that are not normally joined, are both considered recombinant for the puφoses of this invention. It is understood that once a recombinant nucleic acid is made and reintroduced into a host cell or organism, it will replicate non-recombinantly, e.g., using the in vivo cellular machinery of the host cell rather than in vitro manipulations; however, such nucleic acids, once produced recombinantly, although subsequently replicated non- recombinantly, are still considered recombinant for the puφoses of the invention.
Similarly, a "recombinant protein" is a protein made using recombinant techniques, e.g., through the expression of a recombinant nucleic acid as depicted above. A recombinant protein is distinguished from naturally occurring protein by at least one or more characteristics. The protein may be isolated or purified away from some or most of the proteins and compounds with which it is normally associated in its wild type host, and thus may be substantially pure. An isolated protein is unaccompanied by at least some of the material with which it is normally associated in its natural state, preferably constituting at least about 0.5%, more preferably at least about 5% by weight of the total protein in a given sample. A substantially pure protein comprises at least about 75% by weight of the total protein, with at least about 80% being preferred, and at least about 90% being particularly preferred. The definition includes the production of a cancer protein from one organism in a different organism or host cell. Alternatively, the protein may be made at a significantly higher concentration than is normally seen, through the use of an inducible promoter or high expression promoter, such that the protein is made at increased concentration levels. Alternatively, the protein may be in a form not normally found in nature, as in the addition of an epitope tag or amino acid substitutions, insertions and deletions, as discussed below.
The term "heterologous" when used with reference to portions of a nucleic acid indicates that the nucleic acid comprises two or more subsequences that are not normally found in the same relationship to each other in nature. For instance, the nucleic acid is typically recombinantly produced, having two or more sequences, e.g., from unrelated genes arranged to make a new functional nucleic acid, e.g., a promoter from one source and a coding region from another source. Similarly, a heterologous protein will often refer to two or more subsequences that are not found in the same relationship to each other in nature (e.g., a fusion protein). A "promoter" is typically an array of nucleic acid control sequences that direct transcription of a nucleic acid. As used herein, a promoter includes necessary nucleic acid sequences near the start site of transcription, such as, in the case of a polymerase II type promoter, a TATA element. A promoter also optionally includes distal enhancer or repressor elements, which can be located as much as several thousand base pairs from the start site of transcription. A "constitutive" promoter is a promoter that is active under most environmental and developmental conditions. An "inducible" promoter is active under environmental or developmental regulation. The term "operably linked" refers to a functional linkage between a nucleic acid expression control sequence (such as a promoter, or array of transcription factor binding sites) and a second nucleic acid sequence, e.g., wherein the expression control sequence directs transcription of the nucleic acid corresponding to the second sequence. An "expression vector" is a nucleic acid construct, generated recombinantly or synthetically, with a series of specified nucleic acid elements that permit transcription of a particular nucleic acid in a host cell. The expression vector can be part of a plasmid, virus, or nucleic acid fragment. Typically, the expression vector includes a nucleic acid to be transcribed in operable linkage to a promoter. The phrase "selectively (or specifically) hybridizes to" refers to the binding, duplexing, or hybridizing of a molecule selectively to a particular nucleotide sequence under stringent hybridization conditions when that sequence is present in a complex mixture (e.g., total cellular or library DNA or RNA).
The phrase "stringent hybridization conditions" refers to conditions under which a probe will hybridize to its target subsequence, typically in a complex mixture of nucleic acids, but to no other sequences. Stringent conditions are sequence-dependent and will be different in different circumstances. Longer sequences hybridize specifically at higher temperatures. An extensive guide to the hybridization of nucleic acids is found in "Overview of principles of hybridization and the strategy of nucleic acid assays" in Tijssen (1993) Hybridization with Nucleic Probes (Laboratory Techniques in Biochemistry and Molecular Biology) (vol. 24) Elsevier. Generally, stringent conditions are selected to be about 5-10° C lower than the thermal melting point (Tm) for the specific sequence at a defined ionic strength pH. The Tm is the temperature (under defined ionic strength, pH, and nucleic concentration) at which 50% of the probes complementary to the target hybridize to the target sequence at equilibrium (as the target sequences are present in excess, at Tm, 50% of the probes are occupied at equilibrium).
Stringent conditions will be those in which the salt concentration is less than about 1.0 M sodium ion, typically about 0.01-1.0 M sodium ion concentration (or other salts) at pH 7.0 to 8.3 and the temperature is at least about 30° C for short probes (e.g., about 10-50 nucleotides) and at least about 60° C for long probes (e.g., greater than about 50 nucleotides). Stringent conditions may also be achieved with the addition of destabilizing agents such as formamide. For selective or specific hybridization, a positive signal is typically at least two times background, preferably 10 times background hybridization. Exemplary stringent hybridization conditions can be as following: 50% formamide, 5x SSC, and 1% SDS, incubating at 42° C, or, 5x SSC, 1% SDS, incubating at 65° C, with wash in 0.2x SSC, and 0.1% SDS at 65° C. For PCR, a temperature of about 36° C is typical for low stringency amplification, although annealing temperatures may vary between about 32°-48° C depending on primer length. For high stringency PCR amplification, a temperature of about 62° C is typical, although high stringency annealing temperatures can range from about 50-65° C, depending on the primer length and specificity. Typical cycle conditions for both high and low stringency amplifications include a denaturation phase of 90-95° C for 30-120 sec, an annealing phase lasting 30-120 sec, and an extension phase of about 72° C for 1-2 min. Protocols and guidelines for low and high stringency amplification reactions are provided, e.g., in Innis, et al. (1990) PCR Protocols: A Guide to Methods and Applications Academic Press, NY.
Nucleic acids that do not hybridize to each other under stringent conditions are still substantially identical if the polypeptides which they encode are substantially identical. This occurs, e.g., when a copy of a nucleic acid is created using the maximum codon degeneracy permitted by the genetic code. In such cases, the nucleic acids typically hybridize under moderately stringent hybridization conditions. Exemplary "moderately stringent hybridization conditions" include a hybridization in a buffer of 40% formamide, 1 M NaCl, 1% SDS at 37° C, and a wash in IX SSC at 45° C. A positive hybridization is typically at least twice background. Alternative hybridization and wash conditions can be utilized to provide conditions of similar stringency. Additional guidelines for determining hybridization parameters are provided in numerous references, e.g., Ausubel, et al. (eds. 1991 and supplements) Current Protocols in Molecular Biology Wiley.
The phrase "functional effects" in the context of assays for testing compounds that modulate activity of a cancer protein includes the determination of a parameter that is indirectly or directly under the influence of the cancer protein or nucleic acid, e.g., a physiological, functional, physical, or chemical effect, such as the ability to decrease cancer. It includes ligand binding activity; cell viability; cell growth on soft agar; anchorage dependence; contact inhibition and density limitation of growth; cellular proliferation; cellular transformation; growth factor or serum dependence; tumor specific marker levels; invasiveness into Matrigel; tumor growth and metastasis in vivo; mRNA and protein expression in cells undergoing metastasis; and other characteristics of cancer cells. "Functional effects" include in vitro, in vivo, and ex vivo activities.
By "determining the functional effect" is meant assaying for a compound that increases or decreases a parameter that is indirectly or directly under the influence of a cancer protein sequence, e.g., physiological, functional, enzymatic, physical, or chemical effects. Such functional effects can be measured, e.g., changes in spectroscopic characteristics (e.g., fluorescence, absorbance, refractive index), hydrodynamic (e.g., shape), chromatographic, or solubility properties for the protein, measuring inducible markers or transcriptional activation of the cancer protein, measuring binding activity or binding assays, e.g., binding to antibodies or other ligands, and measuring growth, cellular proliferation, cell viability, cellular transformation, growth factor or serum dependence, tumor specific marker levels, invasiveness into Matrigel, tumor growth and metastasis in vivo, mRNA and protein expression, and other characteristics of cancer cells. The functional effects can be evaluated by many means, e.g., microscopy for quantitative or qualitative measures of alterations in moφhological features, measurement of changes in RNA or protein levels for cancer-associated sequences, measurement of RNA stability, identification of downstream or reporter gene expression (CAT, luciferase, /3-gal, GFP, and the like), e.g., via chemiluminescence, fluorescence, colorimetric reactions, antibody binding, inducible markers, and ligand binding assays. "Inhibitors", "activators," and "modulators" of cancer polynucleotide and polypeptide sequences are used to refer to activating, inhibitory, or modulating molecules or compounds identified using in vitro and in vivo assays of cancer polynucleotide and polypeptide sequences. Inhibitors are compounds that, e.g., bind to, partially or totally block activity, decrease, prevent, delay activation, inactivate, desensitize, or down regulate the activity or expression of cancer proteins, e.g., antagonists. Antisense or inhibitory nucleic acids may seem to inhibit expression and subsequent function of the protein. "Activators" are compounds that increase, open, activate, facilitate, enhance activation, sensitize, agonize, or up regulate cancer protein activity. Inhibitors, activators, or modulators also include genetically modified versions of cancer proteins, e.g., versions with altered activity, as well as naturally occurring and synthetic ligands, antagonists, agonists, antibodies, small chemical molecules, and the like. Such assays for inhibitors and activators include, e.g., expressing the cancer protein in vitro, in cells, or cell membranes, applying putative modulator compounds, and then determining the functional effects on activity, as described above. Activators and inhibitors of cancer can also be identified by incubating cancer cells with the test compound and determining increases or decreases in the expression of 1 or more cancer proteins, e.g., 1, 2, 3, 4, 5, 10, 15, 20, 25, 30, 40, 50, or more cancer proteins, such as cancer proteins encoded by the sequences set out in Tables 2A-80.
Samples or assays comprising cancer proteins that are treated with a potential activator, inhibitor, or modulator are compared to control samples without the inhibitor, activator, or modulator to examine the extent of inhibition. Control samples (untreated with inhibitors) are assigned a relative protein activity value of 100%. Inhibition of a polypeptide is achieved when the activity value relative to the control is about 80%, preferably 50%, more preferably 25-0%. Activation of a cancer polypeptide is achieved when the activity value relative to the control (untreated with activators) is about 110%, more preferably 150%, more preferably 200-500% (e.g., two to five fold higher relative to the control), more preferably 1000-3000% higher. The phrase "changes in cell growth" refers to any change in cell growth and proliferation characteristics in vitro or in vivo, such as cell viability, formation of foci, anchorage independence, semi-solid or soft agar growth, changes in contact inhibition and density limitation of growth, loss of growth factor or serum requirements, changes in cell moφhology, gaining or losing immortalization, gaining or losing tumor specific markers, ability to form or suppress tumors when injected into suitable animal hosts, and/or immortalization of the cell.
See, e.g., pp. 231-241 in Freshney (1994) Culture of Animal Cells a Manual of Basic Technique (2d ed.) Wiley-Liss.
"Tumor cell" refers to precancerous, cancerous, and normal cells in a tumor. "Cancer cells," "transformed" cells or "transformation" in tissue culture, refers to spontaneous or induced phenotypic changes that do not necessarily involve the uptake of new genetic material. Although transformation can arise from infection with a transforming virus and incoφoration of new genomic DNA, or uptake of exogenous DNA, it can also arise spontaneously or following exposure to a carcinogen, thereby mutating an endogenous gene. Transformation is associated with phenotypic changes, such as immortalization of cells, aberrant growth control, nonmoφhological changes, and/or malignancy. See, Freshney (2000) Culture of Animal Cells: A Manual of Basic Technique (4th ed.) Wiley-Liss. "Antibody" refers to a polypeptide comprising a framework region from an immunoglobulin gene or fragments thereof that specifically binds and recognizes an antigen. The recognized immunoglobulin genes include the kappa, lambda, alpha, gamma, delta, epsilon, and mu constant region genes, as well as the myriad immunoglobulin variable region genes. Light chains are classified as either kappa or lambda. Heavy chains are classified as gamma, mu, alpha, delta, or epsilon, which in turn define the immunoglobulin classes, IgG, IgM, IgA, IgD, and IgE, respectively. Typically, the antigen-binding region of an antibody or its functional equivalent will be most critical in specificity and affinity of binding. See Paul (ed. 1999) Fundamental Immunology (4th ed.) Raven. An exemplary immunoglobulin (antibody) structural unit comprises a tetramer. Each tetramer is composed of two identical pairs of polypeptide chains, each pair having one "light" (about 25 kD) and one "heavy" chain (about 50-70 kD). The N-terminus of each chain defines a variable region of about 100 to 110 or more amino acids primarily responsible for antigen recognition. The terms variable light chain (Nj_) and variable heavy chain (VJJ) refer to these light and heavy chains respectively.
Antibodies exist, e.g., as intact immunoglobulins or as a number of well-characterized fragments produced by digestion with various peptidases. Thus, e.g., pepsin digests an antibody below the disulfide linkages in the hinge region to produce F(ab)*2 a dimer of Fab which itself is a light chain joined to VJJ-CJJI by a disulfide bond. The F(ab)'2 may be reduced under mild conditions to break the disulfide linkage in the hinge region, thereby converting the F(ab)*2 dimer into an Fab' monomer. The Fab1 monomer is essentially Fab with part of the hinge region (see Paul (ed. 1999) Fundamental Immunology (4th ed.) Raven. While various antibody fragments are defined in terms of the digestion of an intact antibody, one of skill will appreciate that such fragments may be synthesized de novo either chemically or by using recombinant DΝA methodology. Thus, the term antibody, as used herein, also includes antibody fragments either produced by the modification of whole antibodies, or those synthesized de novo using recombinant DΝA methodologies (e.g., single chain Fv) or those identified using phage display libraries (see, e.g., McCafferty, et al. (1990) Nature 348:552-554).
For preparation of antibodies, e.g., recombinant, monoclonal, or polyclonal antibodies, many techniques known. See, e.g., Kohler and Milstein (1975) Nature 256:495-497; Kozbor, et al. (1983) Immunology Today 4:72; Cole, et al. (1985) pp. 77-96 in Reisfeld and Sell (1985)
Monoclonal Antibodies and Cancer Therapy Liss; Coligan (1991) Current Protocols in Immunology Lippincott; Harlow and Lane (1988) Antibodies: A Laboratory Manual CSH Press; and Goding (1986) Monoclonal Antibodies: Principles and Practice (2d ed.) Academic Press. Techniques for the production of single chain antibodies (U.S. Patent 4,946,778) can be adapted to produce antibodies to polypeptides of this invention. Also, transgenic mice, or other organisms such as other mammals, may be used to express humanized antibodies.
Alternatively, phage display technology can be used to identify antibodies and heteromeric Fab fragments that specifically bind to selected antigens. See, e.g., McCafferty, et al. (1990) Nature 348:552-554; Marks, et al. (1992) Biotechnology 10:779-783.
A "chimeric antibody" is an antibody molecule in which (a) the constant region, or a portion thereof, is altered, replaced, or exchanged so that the antigen binding site (variable region) is linked to a constant region of a different or altered class, and/or species, or an entirely different molecule which confers new properties to the chimeric antibody, e.g., an enzyme, toxin, hormone, growth factor, drug, effector function, chemoattractant, immune modulator, etc.; or (b) the variable region, or a portion thereof, is altered, replaced, or exchanged with a variable region having a different or altered antigen specificity. Identification of cancer-associated sequences
In one aspect, the expression levels of genes are determined in different patient samples for which diagnosis information is desired, to provide expression profiles. An expression profile of a particular sample is essentially a "fingeφrint" of the state of the sample; while two states may have any particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is characteristic of the state of the cell. That is, normal tissue may be distinguished from cancerous or metastatic cancerous tissue, or cancer tissue or metastatic cancerous tissue can be compared with tissue from surviving cancer patients. By comparing expression profiles of tissue in known different cancer states, information regarding which genes are important (including both up-and down- regulation of genes) in each of these states is obtained. Molecular profiling may distinguish subtypes of a currently collective disease designation, e.g., different forms of a cancer.
The identification of sequences that are differentially expressed in cancer versus non- cancer tissue allows the use of this information in a number of ways. For example, a particular treatment regime may be evaluated: does a chemotherapeutic drug act to down-regulate cancer, and thus tumor growth or recurrence, in a particular patient. Alternatively, a treatment step may induce other markers which may be used as targets to destroy tumor cells. Similarly, diagnosis and treatment outcomes may be done or confirmed by comparing patient samples with the known expression profiles. Maliganant disease may be compared to non-malignant conditions. Metastatic tissue can also be analyzed to determine the stage of cancer in the tissue, or origin of primary tumor, e.g., metastasis from a remote primary site. Furthermore, these gene expression profiles (or individual genes) allow screening of drug candidates with an eye to mimicking or altering a particular expression profile; e.g., screening can be done for drugs that suppress the cancer expression profile. This may be done by making biochips comprising sets of the important cancer genes, which can then be used in these screens. These methods can also be done on the protein basis; that is, protein expression levels of the cancer proteins can be evaluated for diagnostic puφoses or to screen candidate agents. In addition, the cancer nucleic acid sequences can be administered for gene therapy puφoses, including the administration of antisense nucleic acids, or the cancer proteins (including antibodies and other modulators thereof) administered as therapeutic drugs.
Thus the present invention provides nucleic acid and protein sequences that are differentially expressed in cancer relative to normal tissues and/or non-malignant disease, or in different types of related diseases, herein termed "cancer sequences." As outlined below, cancer sequences include those that are up-regulated (e.g., expressed at a higher level) in cancer, as well as those that are down-regulated (e.g., expressed at a lower level). In a preferred embodiment, the cancer sequences are from humans; however, cancer sequences from other organisms may be useful in animal models of disease and drug evaluation; thus, other cancer sequences are provided, from vertebrates, including mammals, including rodents (rats, mice, hamsters, guinea pigs, etc.), primates, farm animals (including sheep, goats, pigs, cows, horses, etc.) and pets (e.g., dogs, cats, etc.). Cancer sequences from other organisms may be obtained using the techniques outlined below. Cancer sequences can include both nucleic acid and amino acid sequences. In a preferred embodiment, the skin cancer sequences are recombinant nucleic acids. These nucleic acid sequences are useful in a variety of applications, including diagnostic applications, which will detect naturally occurring nucleic acids, as well as screening applications; e.g., biochips comprising nucleic acid probes or PCR microtiter plates with selected probes to the cancer sequences.
A cancer sequence can be initially identified by substantial nucleic acid and/or amino acid sequence homology to the cancer sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, e.g., using homology programs or hybridization conditions.
For identifying cancer-associated sequences, the cancer screen typically includes comparing genes identified in different tissues, e.g., normal and cancerous tissues, cancer and non-malignant conditions, non-malignant conditions and normal tissues, or tumor tissue samples from patients who have metastatic disease vs. non metastatic tissue. Other suitable tissue comparisons include comparing cancer samples with metastatic cancer samples from other cancers, such as lung, stomach, gastrointestinal cancers, etc. Samples of different stages of cancer, e.g., survivor tissue, drug resistant states, and tissue undergoing metastasis, are applied to biochips comprising nucleic acid probes. The samples are first microdissected, if applicable, and treated for preparation of mRNA. Suitable biochips are commercially available, e.g., from Affymetrix, Santa Clara, CA. Gene expression profiles as described herein are generated and the data analyzed.
In one embodiment, the genes showing changes in expression as between normal and disease states are compared to genes expressed in other normal tissues, including, and not limited to lung, heart, brain, liver, stomach, kidney, muscle, colon, small intestine, large intestine, spleen, bone, and/or placenta. In a preferred embodiment, those genes identified during the cancer screen that are expressed in a significant amount in other tissues (e.g., essential organs) are removed from the profile, although in some embodiments, this is not necessary (e.g., where organs may be dispensible, e.g., female or male specific). That is, when screening for drugs, it is usually preferable that the target expression be disease specific, to minimize possible side effects on other organs were there expression.
In a preferred embodiment, cancer sequences are those that are up-regulated in cancer; that is, the expression of these genes is higher in the cancer tissue as compared to non-cancer or non-malignant tissue. "Up-regulation" as used herein often means at least about a two-fold change, preferably at least about a three fold change, with at least about five-fold or higher being preferred. Another embodiment is directed to sequences up-regulated in non-malignant conditions relative to normal. Uniformity among relevant samples is also preferred.
Unigene cluster identification numbers and accession numbers herein are for the GenBank sequence database and the sequences of the accession numbers are hereby expressly incoφorated by reference. GenBank is available, see, e.g., Benson, et al. (1998) Nuc. Acids Res. 26:1-7; and http://www.ncbi.nlm.nih.gov/. Sequences are also available in other databases, e.g., European Molecular Biology Laboratory (EMBL) and DNA Database of Japan (DDBJ). In some situations, the sequences may be derived from assembly of available sequences or be predicted from genomic DNA using exon prediction algorithms, such as FGENESH. See Salamov and Solovyev (2000) Genome Res. 10:516-522. In other situations, sequences have been derived from cloning and sequencing of isolated nucleic acids.
In another preferred embodiment, cancer sequences are those that are down-regulated in the cancer; that is, the expression of these genes is lower in cancer tissue as compared to non- cancerous tissue. "Down-regulation" as used herein often means at least about a two-fold change, preferably at least about a three fold change, with at least about five-fold or higher being preferred. Informatics
The ability to identify genes that are over or under expressed in cancer can additionally provide high-resolution, high-sensitivity datasets which can be used in the areas of diagnostics, therapeutics, drug development, pharmacogenetics, protein structure, biosensor development, and other related areas. For example, the expression profiles can be used in diagnostic or prognostic evaluation of patients with cancer or related diseases. See Tables 1-3. Or as another example, subcellular toxicological information can be generated to better direct drug structure and activity correlation (see Anderson (June 11-12, 1998) Pharmaceutical Proteomics: Targets, Mechanism, and Function, paper presented at the JJ3C Proteomics conference, Coronado, CA). Subcellular toxicological information can also be utilized in a biological sensor device to predict the likely toxicological effect of chemical exposures and likely tolerable exposure thresholds (see U.S. Patent No. 5,811,231). Similar advantages accrue from datasets relevant to other biomolecules and bioactive agents (e.g., nucleic acids, saccharides, lipids, drugs, and the like). Thus, in another embodiment, the present invention provides a database that includes at least one set of assay data. The data contained in the database is acquired, e.g., using array analysis either singly or in a library format. The database can be in a form in which data can be maintained and transmitted, but is preferably an electronic database. The electronic database of the invention can be maintained on any electronic device allowing for the storage of and access to the database, such as a personal computer, but is preferably distributed on a wide area network, such as the World Wide Web. The focus of the present section on databases that include peptide sequence data is for clarity of illustration only. Similar databases can be assembled for assay data acquired using an assay of the invention.
The compositions and methods for identifying and/or quantitating the relative and/or absolute abundance of a variety of molecular and macromolecular species from a biological sample representing cancer, e.g., the identification of cancer-associated sequences described herein, provide an abundance of information which can be correlated with pathological conditions, predisposition to disease, drug testing, therapeutic monitoring, gene-disease causal linkages, identification of correlates of immunity and physiological status, among others. Although the data generated from the assays of the invention is suited for manual review and analysis, in a preferred embodiment, data processing using high-speed computers is utilized.
An array of methods for indexing and retrieving biomolecular information is available. For example, U.S. Patents 6,023,659 and 5,966,712 disclose a relational database system for storing biomolecular sequence information in a manner that allows sequences to be catalogued and searched according to one or more protein function hierarchies. U.S. Patent 5,953,727 discloses a relational database having sequence records containing information in a format that allows a collection of partial-length DNA sequences to be catalogued and searched according to association with one or more sequencing projects for obtaining full-length sequences from the collection of partial length sequences. U.S. Patent 5,706,498 discloses a gene database retrieval system for making a retrieval of a gene sequence similar to a sequence data item in a gene database based on the degree of similarity between a key sequence and a target sequence. U.S. Patent 5,538,897 discloses a method using mass spectroscopy fragmentation patterns of peptides to identify amino acid sequences in computer databases by comparison of predicted mass spectra with experimentally-derived mass spectra using a closeness-of-fit measure. U.S. Patent 5,926,818 discloses a multi-dimensional database comprising a functionality for multidimensional data analysis described as on-line analytical processing (OLAP), which entails the consolidation of projected and actual data according to more than one consolidation path or dimension. U.S. Patent 5,295,261 reports a hybrid database structure in which the fields of each database record are divided into two classes, navigational and informational data, with navigational fields stored in a hierarchical topological map which can be viewed as a tree structure or as the merger of two or more such tree structures. See also Baxevanis, et al. (2001) Bioinformatics: A Practical Guuide to the Analysis of Genes and Proteins Wiley; Mount (2001) Bioinformatics: Sequence and Genome Analysis CSH Press, NY; Durbin, et al. (eds. 1999) Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids Cambridge University Press; Baxevanis and Oeullette (eds. 1998) Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (2d. ed.) Wiley-Liss; Rashidi and Buehler (1999) Bioinformatics: Basic Applications in Biological Science and Medicine CRC Press; Setubal, et al. (eds. 1997) Introduction to Computational Molecular Biology Brooks/Cole; Misener and Krawetz (eds. 2000) Bioinformatics: Methods and Protocols Humana Press; Higgins and Taylor (eds. 2000) Bioinformatics: Sequence, Structure, and Databanks: A Practical Approach Oxford University Press; Brown (2001) Bioinformatics: A Biologist's Guide to Biocomputing and the Internet Eaton Pub.: Han and Kamber (2000) Data Mining: Concepts and Techniques Kaufmann Pub.; and Waterman (1995) Introduction to Computational Biology: Maps. Sequences, and Genomes Chap and Hall.
The present invention provides a computer database comprising a computer and software for storing in computer-retrievable form assay data records cross-tabulated, e.g., with data specifying the source of the target-containing sample from which each sequence specificity record was obtained.
In an exemplary embodiment, at least one of the sources of target-containing sample is from a control tissue sample known to be free of pathological disorders. In a variation, at least one of the sources is a known pathological tissue specimen, e.g., a neoplastic lesion or another tissue specimen to be analyzed for cancer. In another variation, the assay records cross-tabulate one or more of the following parameters for each target species in a sample: (1) a unique identification code, which can include, e.g., a target molecular structure and/or characteristic separation coordinate (e.g., electrophoretic coordinates); (2) sample source; and (3) absolute and/or relative quantity of the target species present in the sample. The invention also provides for the storage and retrieval of a collection of target data in a computer data storage apparatus, which can include magnetic disks, optical disks, magneto- optical disks, DRAM, SRAM, SGRAM, SDRAM, RDRAM, DDR RAM, magnetic bubble memory devices, and other data storage devices, including CPU registers and on-CPU data storage arrays. Typically, the target data records are stored as a bit pattern in an array of magnetic domains on a magnetizable medium or as an array of charge states or transistor gate states, such as an array of cells in a DRAM device (e.g., each cell comprised bf a transistor and a charge storage area, which may be on the transistor). In one embodiment, the invention provides such storage devices, and computer systems built therewith, comprising a bit pattern encoding a protein expression fingeφrint record comprising unique identifiers for at least 10 target data records cross-tabulated with target source.
When the target is a peptide or nucleic acid, the invention preferably provides a method for identifying related peptide or nucleic acid sequences, comprising performing a computerized comparison between a peptide or nucleic acid sequence assay record stored in or retrieved from a computer storage device or database and at least one other sequence. The comparison can include a sequence analysis or comparison algorithm or computer program embodiment thereof (e.g., FASTA, TFASTA, GAP, BESTFIT) and/or the comparison may be of the relative amount of a peptide or nucleic acid sequence in a pool of sequences determined from a polypeptide or nucleic acid sample of a specimen.
The invention also preferably provides a magnetic disk, such as an IBM-compatible (DOS, Windows, Windows95/98/2000, Windows NT, OS/2) or other format (e.g., Linux, SunOS, Solaris, AIX, SCO Unix, VMS, MV, Macintosh, etc.) floppy diskette or hard (fixed, Winchester) disk drive, comprising a bit pattern encoding data from an assay of the invention in a file format suitable for retrieval and processing in a computerized sequence analysis, comparison, or relative quantitation method.
The invention also provides a network, comprising a plurality of computing devices linked via a data link, such as an Ethernet cable (coax or lOBaseT), telephone line, ISDN line, wireless network, optical fiber, or other suitable signal transmission medium, whereby at least one network device (e.g., computer, disk array, etc.) comprises a pattern of magnetic domains (e.g., magnetic disk) and/or charge domains (e.g., an array of DRAM cells) composing a"bit pattern encoding data acquired from an assay of the invention.
The invention also provides a method for transmitting assay data that includes generating an electronic signal on an electronic communications device, such as a modem, ISDN terminal adapter, DSL, cable modem, ATM switch, or the like, wherein the signal includes (in native or encrypted format) a bit pattern encoding data from an assay or a database comprising a plurality of assay results obtained by the method of the invention.
In a preferred embodiment, the invention provides a computer system for comparing a query target to a database containing an array of data structures, such as an assay result obtained by the method of the invention, and ranking database targets based on the degree of identity and gap weight to the target data. A central processor is preferably initialized to load and execute the computer program for alignment and/or comparison of the assay results. Data for a query target is entered into the central processor via an I/O device. Execution of the computer program results in the central processor retrieving the assay data from the data file, which comprises a binary description of an assay result. The target data or record and the computer program can be transferred to secondary memory, which is typically random access memory (e.g., DRAM, SRAM, SGRAM, or SDRAM). Targets are ranked according to the degree of correspondence between a selected assay characteristic (e.g., binding to a selected affinity moiety) and the same characteristic of the query target and results are output via an I/O device. For example, a central processor can be a conventional computer (e.g., Intel Pentium, PowerPC, Alpha, PA-8000, SPARC, MIPS 4400, MIPS 10000, VAX, etc.); a program can be a commercial or public domain molecular biology software package (e.g., UWGCG Sequence Analysis Software, Darwin); a data file can be an optical or magnetic disk, a data server, a memory device (e.g., DRAM, SRAM, SGRAM, SDRAM, EPROM, bubble memory, flash memory, etc.); an I/O device can be a terminal comprising a video display and a keyboard, a modem, an ISDN terminal adapter, an Ethernet port, a punched card reader, a magnetic strip reader, or other suitable I/O device.
The invention also preferably provides the use of a computer system, such as that described above, which comprises: (1) a computer; (2) a stored bit pattern encoding a collection of peptide sequence specificity records obtained by the methods of the invention, which may be stored in the computer; (3) a comparison target, such as a query target; and (4) a program for alignment and comparison, typically with rank-ordering of comparison results on the basis of computed similarity values. See, e.g., Ewens and Grant (2001) Statistical Methods in Bioinformatics: An Introduction Springer- Verlag. Mathematical approaches can also be used to conclude whether similarities or differences in the gene expression exhibited by different samples are significant. See, e.g., Golub, et al. (1999) Science 286:531-537; Duda, et al. (2001) Pattern Classification Wiley; and Hastie, et al. (2001) The Elements of Statistical Learning: Data Mining, Inference, and Prediction Springer- Verlag. One approach to determine whether a sample is more similar to or has maximum similarity with a given condition between the sample and one or more pools representing different conditions for comparison; the pool with the smallest vector angle is then chosen as the most similar to the biological sample among the pools compared. Characteristics of cancer-associated proteins
Cancer proteins of the present invention may be classified as secreted proteins, transmembrane proteins, or intracellular proteins. In one embodiment, the cancer protein is an intracellular protein. Intracellular proteins may be found in the cytoplasm and/or in the nucleus. Intracellular proteins are involved in all aspects of cellular function and replication (including, e.g., signaling pathways); aberrant expression of such proteins often results in unregulated or disregulated cellular processes (see, e.g., Alberts, et al. (eds. 1994) Molecular Biology of the Cell (3d ed.) Garland). For example, many intracellular proteins have enzymatic activity such as protein kinase activity, protein phosphatase activity, protease activity, nucleotide cyclase activity, polymerase activity, and the like. Intracellular proteins also serve as docking proteins that are involved in organizing complexes of proteins, or targeting proteins to various subcellular localizations, and are involved in maintaining the structural integrity of organelles.
An increasingly appreciated concept in characterizing proteins is the presence in the proteins of one or more structural motifs for which defined functions have been attributed. In addition to the highly conserved sequences found in the enzymatic domain of proteins, highly conserved sequences have been identified in proteins that are involved in protein-protein interaction. For example, Src-homology-2 (SH2) domains bind tyrosine-phosphorylated targets in a sequence dependent manner. PTB domains, which are distinct from SH2 domains, also bind tyrosine phosphorylated targets. SH3 domains bind to proline-rich targets. In addition, PH domains, tetratricopeptide repeats and WD domains to name only a few, have been shown to mediate protein-protein interactions. Some of these may also be involved in binding to phospholipids or other second messengers. These motifs can be identified on the basis of amino acid sequence; thus, an analysis of the sequence of proteins may provide insight into both the enzymatic potential of the molecule and/or molecules with which the protein may associate. One useful database is Pfam (protein families), which is a large collection of multiple sequence alignments and hidden Markov models covering many common protein domains. Versions are available via the internet from Washington University in St. Louis, the S anger Center in England, and the Karolinska Institute in Sweden. See, e.g., Bateman, et al. (2000) Nuc. Acids Res. 28:263-266; Sonnhammer, et al. (1997) Proteins 28:405-420 ; Bateman, et al. (1999) Nuc. Acids Res. 27:260-262; and Sonnhammer, et al. (1998) Nuc. Acids Res. 26:320-322. In another embodiment, the cancer sequences are transmembrane proteins. Transmembrane proteins are molecules that span a phospholipid bilayer of a cell. They may have an intracellular domain, an extracellular domain, or both. The intracellular domains of such proteins may have a number of functions including those already described for intracellular proteins. For example, the intracellular domain may have enzymatic activity and/or may serve as a binding site for additional proteins. Frequently the intracellular domain of transmembrane proteins serves both roles. For example certain receptor tyrosine kinases have both protein kinase activity and SH2 domains. In addition, autophosphorylation of tyrosines on the receptor molecule itself, creates binding sites for additional SH2 domain containing proteins.
Transmembrane proteins may contain from one to many transmembrane domains. For example, receptor tyrosine kinases, certain cytokine receptors, receptor guanylyl cyclases and receptor serine/threonine protein kinases contain a single transmembrane domain. However, various other proteins including channels and adenylyl cyclases contain numerous transmembrane domains. Many important cell surface receptors such as G protein coupled receptors (GPCRs) are classified as "seven transmembrane domain" proteins, as they contain 7 membrane spanning regions. Characteristics of transmembrane domains include approximately 17 consecutive hydrophobic amino acids that may be followed by charged amino acids. Therefore, upon analysis of the amino acid sequence of a particular protein, the localization and number of transmembrane domains within the protein maybe predicted (see, e.g., PSORT web site http://psort.nibb.ac.jp/). Important transmembrane protein receptors include, but are not limited to the insulin receptor, insulin-like growth factor receptor, human growth hormone receptor, glucose transporters, transferrin receptor, epidermal growth factor receptor, low density lipoprotein receptor, epidermal growth factor receptor, leptin receptor, and interleukin receptors, e.g., IL-1 receptor, E -2 receptor, etc.
The extracellular domains of transmembrane proteins are diverse; however, conserved motifs are found repeatedly among various extracellular domains. Conserved structure and/or functions have been ascribed to different extracellular motifs. Many extracellular domains are involved in binding to other molecules. In one aspect, extracellular domains are found on receptors. Factors that bind the receptor domain include circulating ligands, which may be peptides, proteins, or small molecules such as adenosine and the like. For example, growth factors such as EGF, FGF, and PDGF are circulating growth factors that bind to their cognate receptors to initiate a variety of cellular responses. Other factors include cytokines, mitogenic factors, neurotrophic factors, and the like. Extracellular domains also bind to cell-associated molecules. In this respect, they may mediate cell-cell interactions. Cell-associated ligands can be tethered to the cell, e.g., via a glycosylphosphatidylinositol (GPI) anchor, or may themselves be transmembrane proteins. Extracellular domains may also associate with the extracellular matrix and contribute to the maintenance of the cell structure. Cancer proteins that are transmembrane are particularly preferred in the present invention as they are readily accessible targets for immunotherapeutics, as are described herein. In addition, as outlined below, transmembrane proteins can be also useful in imaging modalities. Antibodies may be used to label such readily accessible proteins in situ. Alternatively, antibodies can also label intracellular proteins, in which case samples are typically permeablized to provide access to intracellular proteins. In addition, some membrane proteins can be processed to release a soluble protein, or to expose a residual fragment. Released soluble proteins may be useful diagnostic markers, processed residual protein fragments may be useful lung markers of disease.
It will also be appreciated that a transmembrane protein can be made soluble by removing transmembrane sequences, e.g., through recombinant methods. Furthermore, transmembrane proteins that have been made soluble can be made to be secreted through recombinant means by adding an appropriate signal sequence.
In another embodiment, the cancer proteins are secreted proteins; the secretion of which can be either constitutive or regulated. These proteins may have a signal peptide or signal sequence that targets the molecule to the secretory pathway. Secreted proteins are involved in numerous physiological events; e.g., if circulating, they often serve to transmit signals to various other cell types. The secreted protein may function in an autocrine manner (acting on the cell that secreted the factor), a paracrine manner (acting on cells in close proximity to the cell that secreted the factor), an endocrine manner (acting on cells at a distance, e.g, secretion into the blood stream), or exocrine (secretion, e.g., through a duct or to adjacent epithelial surface as sweat glands, sebaceous glands, pancreatic ducts, lacrimal glands, mammary glands, wax producing glands of the ear, etc.). Thus secreted molecules often find use in modulating or altering numerous aspects of physiology. Cancer proteins that are secreted proteins are particularly preferred in the present invention as they serve as good targets for diagnostic markers, e.g., for blood, plasma, serum, or stool tests. Those which are enzymes may be antibody or small molecule targets. Others may be useful as vaccine targets, e.g., via CTL mechanisms. Use of cancer nucleic acids
As described above, cancer sequence is initially identified by substantial nucleic acid and/or amino acid sequence homology or linkage to the cancer sequences outlined herein. Such homology can be based upon the overall nucleic acid or amino acid sequence, and is generally determined as outlined below, using either homology programs or hybridization conditions. Typically, linked sequences on a mRNA are found on the same molecule.
As detailed elsewhere, percent identity can be determined using an algorithm such as BLAST. A preferred method utilizes the BLASTN module of WU-BLAST-2 set to the default parameters, with overlap span and overlap fraction set to 1 and 0.125, respectively. Alignment may include the introduction of gaps in the sequences to be aligned. In addition, for sequences which contain either more or fewer nucleotides than those of the nucleic acids described, the percentage of homology may be determined based on the number of homologous nucleosides in relation to the total number of nucleosides. Thus, e.g., homology of sequences shorter than those of the sequences identified will be determined using the number of nucleosides in the shorter sequence.
In one embodiment, the nucleic acid homology is determined through hybridization studies. Thus, e.g., nucleic acids which hybridize under high stringency to a described nucleic acid, or its complement, or is also found on naturally occurring mRNAs is considered a cancer sequence. In another embodiment, less stringent hybridization conditions are used; e.g., moderate or low stringency conditions may be used; see Ausubel, supra, and Tijssen, supra. The cancer nucleic acid sequences of the invention, e.g., the sequences in Tables 1-80, can be fragments of larger genes, e.g., they are nucleic acid segments. "Genes" in this context includes coding regions, non-coding regions, and mixtures of coding and non-coding regions. Accordingly, using the sequences provided herein, extended sequences, in either direction, of the cancer genes can be obtained, using techniques well known for cloning either longer sequences or the full length sequences; see Ausubel, et al., supra. Much can be done by informatics and many sequences can be clustered to include multiple sequences corresponding to a single gene, e.g., systems such as UniGene (see, http://www.ncbi.nlm.nih.gov/UniGene/).
Once a cancer nucleic acid is identified, it can be cloned and, if necessary, its constituent parts recombined to form the entire cancer nucleic acid coding regions or the entire mRNA sequence. Once isolated from its natural source, e.g., contained within a plasmid or other vector or excised therefrom as a linear nucleic acid segment, the recombinant cancer nucleic acid can be further used as a probe to identify and isolate other cancer nucleic acids, e.g., extended coding regions. It can also be used as a "precursor" nucleic acid to make modified or variant cancer nucleic acids and proteins.
The cancer nucleic acids of the present invention are used in several ways. In one embodiment, nucleic acid probes to the cancer nucleic acids are made and attached to biochips to be used in screening and diagnostic methods, as outlined below, or for administration, e.g., for gene therapy, vaccine, RNAi, and/or antisense applications. Alternatively, cancer nucleic acids that include coding regions of cancer proteins can be put into expression vectors for the expression of cancer proteins, again for screening puφoses or for administration to a patient. In a preferred embodiment, nucleic acid probes to cancer nucleic acids (both the nucleic acid sequences outlined in the figures and/or the complements thereof) are made. The nucleic acid probes attached to the biochip are designed to be substantially complementary to the cancer nucleic acids, e.g., the target sequence (either the target sequence of the sample or to other probe sequences, e.g., in sandwich assays), such that hybridization of the target sequence and the probes of the present invention occurs. As outlined below, this complementarity need not be perfect; there may be any number of base pair mismatches which will interfere with hybridization between the target sequence and the single stranded nucleic acids of the present invention. However, if the number of mutations is so great that no hybridization can occur under even the least stringent of hybridization conditions, the sequence is not a complementary target sequence. Thus, by "substantially complementary" herein is meant that the probes are sufficiently complementary to the target sequences to hybridize under normal reaction conditions, particularly high stringency conditions, as outlined herein.
A nucleic acid probe is generally single stranded but can be partially single and partially double stranded. The strandedness of the probe is dictated by the structure, composition, and properties of the target sequence. In general, the nucleic acid probes range from about 8-100 bases long, with from about 10-80 bases being prefened, and from about 30-50 bases being particularly preferred. That is, generally whole genes are not used. In some embodiments, much longer nucleic acids can be used, up to hundreds of bases.
In a preferred embodiment, more than one probe per sequence is used, with either overlapping probes or probes to different sections of the target being used. That is, two, three, four or more probes, with three being preferred, are used to build in a redundancy for a particular target. The probes can be overlapping (e.g., have some sequence in common), or separate. In some cases, PCR primers may be used to amplify signal for higher sensitivity. Nucleic acids can be attached or immobilized to a solid support in a wide variety of ways. By "immobilized" and grammatical equivalents herein is meant the association or binding between the nucleic acid probe and the solid support is sufficient to be stable under the conditions of binding, washing, analysis, and removal as outlined. The binding can typically be covalent or non-covalent. By "non-covalent binding" and grammatical equivalents herein is meant one or more of electrostatic, hydrophilic, and hydrophobic interactions. Included in non- covalent binding is the covalent attachment of a molecule, e.g., streptavidin to the support and the non-covalent binding of the biotinylated probe to the streptavidin. By "covalent binding" and grammatical equivalents herein is meant that the two moieties, the solid support and the probe, are attached by at least one bond, including sigma bonds, pi bonds, and coordination bonds. Covalent bonds can be formed directly between the probe and the solid support or can be formed by a cross linker or by inclusion of a specific reactive group on either the solid support or the probe or both molecules. Immobilization may also involve a combination of covalent and non-covalent interactions.
In general, the probes are attached to the biochip in a wide variety of ways. As described herein, the nucleic acids can either be synthesized first, with subsequent attachment to the biochip, or can be directly synthesized on the biochip. The biochip comprises a suitable solid substrate. By "substrate" or "solid support" or other grammatical equivalents herein is meant a material that can be modified for the attachment or association of the nucleic acid probes and is amenable to at least one detection method. Often, the substrate may contain discrete individual sites appropriate for individual partitioning and identification. The number of possible substrates is very large, and include, but are not limited to, glass and modified or functionalized glass, plastics (including acrylics, polystyrene and copolymers of styrene and other materials, polypropylene, polyethylene, polybutylene, polyurethanes, TeflonJ, etc.), polysaccharides, nylon or nitrocellulose, resins, silica or silica-based materials including silicon and modified silicon, carbon, metals, inorganic glasses, plastics, etc. In general, the substrates allow optical detection and do not appreciably fluoresce. See WO 0055627.
Generally the substrate is planar, although other configurations of substrates may be used as well. For example, the probes may be placed on the inside surface of a tube for flow- through sample analysis to minimize sample volume. Similarly, the substrate may be flexible, such as a flexible foam, including closed cell foams made of particular plastics.
In a preferred embodiment, the surface of the biochip and the probe may be derivatized with chemical functional groups for subsequent attachment of the two. Thus, e.g., the biochip is derivatized with a chemical functional group including, but not limited to, amino groups, carboxy groups, oxo groups, and thiol groups, with amino groups being particularly preferred. Using these functional groups, the probes can be attached using functional groups on the probes. For example, nucleic acids containing amino groups can be attached to surfaces comprising amino groups, e.g., using linkers; e.g., homo-or hetero-bifunctional linkers as are well known (see 1994 Pierce Chemical Company catalog, technical section on cross-linkers, pages 155-
200). In addition, in some cases, additional linkers, such as alkyl groups (including substituted and heteroalkyl groups) may be used.
In this embodiment, oligonucleotides are synthesized, and then attached to the surface of the solid support. Either the 5' or 3' terminus may be attached to the solid support, or attachment may be via linkage to an internal nucleoside. In another embodiment, the immobilization to the solid support may be very strong, yet non-covalent. For example, biotinylated oligonucleotides can be made, which bind to surfaces covalently coated with streptavidin, resulting in attachment.
Alternatively, the oligonucleotides may be synthesized on the surface. For example, photoactivation techniques utilizing photopolymerization compounds and techniques are used. In a preferred embodiment, the nucleic acids can be synthesized in situ, using known photolithographic techniques, such as those described in WO 95/25116; WO 95/35505; U.S. Patent Nos. 5,700,637 and 5,445,934; and references cited within, all of which are expressly incoφorated by reference; these methods of attachment form the basis of the Affymetrix GeneChip™ technology.
Often, amplification-based assays are performed to measure the expression level of cancer-associated sequences. These assays are typically performed in conjunction with reverse transcription. In such assays, a cancer-associated nucleic acid sequence acts as a template in an amplification reaction (e.g., Polymerase Chain Reaction, or PCR). In a quantitative amplification, the amount of amplification product will be proportional to the amount of template in the original sample. Comparison to appropriate controls provides a measure of the amount of cancer-associated RNA. Methods of quantitative amplification are well known. Detailed protocols for quantitative PCR are provided, e.g., in Innis, et al. (1990) PCR Protocols: A Guide to Methods and Applications Academic Press.
In some embodiments, a TaqMan based assay is used to measure expression. TaqMan based assays use a fluorogenic oligonucleotide probe that contains a 5' fluorescent dye and a 3' quenching agent. The probe hybridizes to a PCR product, but cannot itself be extended due to a blocking agent at the 3' end. When the PCR product is amplified in subsequent cycles, the 5' nuclease activity of the polymerase, e.g., AmpliTaq, results in the cleavage of the TaqMan probe. This cleavage separates the 5' fluorescent dye and the 3' quenching agent, thereby resulting in an increase in fluorescence as a function of amplification (see, e.g., literature provided by Perkin-Elmer, e.g., www2.perkin-elmer.com).
Other suitable amplification methods include, but are not limited to, ligase chain reaction (LCR) (see Wu and Wallace (1989) Genomics 4:560-569, Landegren, et al. (1988) Science 241:1077-1080, and Barringer, et al. (1990) Gene 89:117-122), transcription amplification (Kwoh, et al. (1989) Proc. Natl. Acad. Sci. USA 86:1173-1177), self-sustained sequence replication (Guatelli, et al. (1990) Proc. Natl. Acad. Sci. USA 87:1874- 1878), dot PCR, linker adapter PCR, etc. Expression of cancer proteins from nucleic acids
In a preferred embodiment, cancer nucleic acids, e.g., encoding cancer proteins, are used to make a variety of expression vectors to express cancer proteins which can then be used in screening assays, as described below. Expression vectors and recombinant DNA technology are well known (see, e.g., Ausubel, supra, and Fernandez and Hoeffier (eds. 1999) Gene Expression Systems Academic Press) to express proteins. The expression vectors may be either self replicating extrachromosomal vectors or vectors which integrate into a host genome. Generally, these expression vectors include transcriptional and translational regulatory nucleic acid operably linked to the nucleic acid encoding the cancer protein. The term "control sequences" refers to DNA sequences used for the expression of an operably linked coding sequence in a particular host organism. Control sequences that are suitable for prokaryotes, e.g., include a promoter, optionally an operator sequence, and a ribosome binding site. Eukaryotic cells are known to utilize promoters, polyadenylation signals, and enhancers. Nucleic acid is "operably linked" when it is placed into a functional relationship with another nucleic acid sequence. For example, DNA for a presequence or secretory leader is operably linked to DNA for a polypeptide if it is expressed as a preprotein that participates in the secretion of the polypeptide; a promoter or enhancer is operably linked to a coding sequence if it affects the transcription of the sequence; or a ribosome binding site is operably linked to a coding sequence if it is positioned so as to facilitate translation. Generally, "operably linked" means that the DNA sequences being linked are contiguous, and, in the case of a secretory leader, contiguous and in reading phase. However, enhancers do not have to be contiguous. Linking is typically accomplished by ligation at convenient restriction sites. If such sites do not exist, synthetic oligonucleotide adaptors or linkers are used in accordance with conventional practice. Transcriptional and translational regulatory nucleic acid will generally be appropriate to the host cell used to express the cancer protein. Numerous types of appropriate expression vectors and suitable regulatory sequences are known for a variety of host cells.
In general, transcriptional and translational regulatory sequences may include, but are not limited to, promoter sequences, ribosomal binding sites, transcriptional start and stop sequences, translational start and stop sequences, and enhancer or activator sequences. In a preferred embodiment, the regulatory sequences include a promoter and transcriptional start and stop sequences.
Promoter sequences may be either constitutive or inducible promoters. The promoters may be either naturally occurring promoters or hybrid promoters. Hybrid promoters, which combine elements of more than one promoter, are also known, and are useful in the present invention. An expression vector may comprise additional elements. For example, the expression vector may have two replication systems, thus allowing it to be maintained in two organisms, e.g., in mammalian or insect cells for expression and in a prokaryotic host for cloning arid amplification. Furthermore, for integrating expression vectors, the expression vector often contains at least one sequence homologous to the host cell genome, and preferably two homologous sequences which flank the expression construct. The integrating vector may be directed to a specific locus in the host cell by selecting the appropriate homologous sequence for inclusion in the vector. Constructs for integrating vectors are available. See, e.g., Fernandez and Hoeffler, supra; and Kitamura, et al. (1995) Proc. Nat'l Acad. Sci. USA 92:9146- 9150. In addition, in a preferred embodiment, the expression vector contains a selectable marker gene to allow the selection of transformed host cells. Selection genes are well known and will vary with the host cell used. The cancer proteins of the present invention are usually produced by culturing a host cell transformed with an expression vector containing nucleic acid encoding a cancer protein, under the appropriate conditions to induce or cause expression of the cancer protein. Conditions appropriate for cancer protein expression will vary with the choice of the expression vector and the host cell, and will be easily ascertained through routine experimentation or optimization. For example, the use of constitutive promoters in the expression vector will require optimizing the growth and proliferation of the host cell, while the use of an inducible promoter requires the appropriate growth conditions for induction. In addition, in some embodiments, the timing of the harvest is important. For example, the baculoviral systems used in insect cell expression are lytic viruses, and thus harvest time selection can be crucial for product yield.
Appropriate host cells include yeast, bacteria, archaebacteria, fungi, and insect and animal cells, including mammalian cells. Of particular interest are Saccharomyces cerevisiae and other yeasts, E. coli, Bacillus subtilis, Sf9 cells, C129 cells, 293 cells, Neurospora, BHK, CHO, COS, HeLa cells, HUVEC (human umbilical vein endothelial cells), THP1 cells (a macrophage cell line), and various other human cells and cell lines.
In a preferred embodiment, the cancer proteins are expressed in mammalian cells. Mammalian expression systems may be used, and include retroviral and adenoviral systems. One expression vector system is a retroviral vector system such as is generally described in PCT/US97/01019 and PCT/US97/01048. Of particular use as mammalian promoters are the promoters from mammalian viral genes, since the viral genes are often highly expressed and have a broad host range. Examples include the SV40 early promoter, mouse mammary tumor virus LTR promoter, adenovirus major late promoter, heφes simplex virus promoter, and the CMV promoter (see, e.g., Fernandez and Hoeffler, supra). Typically, transcription termination and polyadenylation sequences recognized by mammalian cells are regulatory regions located 3' to the translation stop codon and thus, together with the promoter elements, flank the coding sequence. Examples of transcription terminator and polyadenlyation signals include those derived from SV40.
Methods of introducing exogenous nucleic acid into mammalian hosts, as well as other hosts, are available, and will vary with the host cell used. Techniques include dextran-mediated transfection, calcium phosphate precipitation, polybrene mediated transfection, protoplast fusion, electroporation, viral infection, encapsulation of the polynucleotide(s) in liposomes, and direct microinjection of the DNA into nuclei. In a preferred embodiment, cancer proteins are expressed in bacterial systems. Promoters from bacteriophage may also be used. In addition, synthetic promoters and hybrid promoters are also useful; e.g., the tac promoter is a hybrid of the frp and lac promoter sequences. Furthermore, a bacterial promoter can include naturally occurring promoters of non- bacterial origin that have the ability to bind bacterial RNA polymerase and initiate transcription. In addition to a functioning promoter sequence, an efficient ribosome binding site is desirable. The expression vector may also include a signal peptide sequence that provides for secretion of the cancer protein in bacteria. The protein is either secreted into the growth media (gram- positive bacteria) or into the periplasmic space, located between the inner and outer membrane of the cell (gram-negative bacteria). The bacterial expression vector may also include a selectable marker gene to allow for the selection of bacterial strains that have been transformed. Suitable selection genes include genes which render the bacteria resistant to drugs such as ampicillin, chloramphenicol, erythromycin, kanamycin, neomycin, and tetracycline. Selectable markers also include biosynthetic genes, such as those in the histidine, tryptophan, and leucine biosynthetic pathways. These components are assembled into expression vectors. Expression vectors for bacteria are well known, and include vectors for Bacillus subtilis, E. coli, Streptococcus cremoris, and Streptococcus lividans, among others (e.g., Fernandez and Hoeffler, supra). The bacterial expression vectors are transformed into bacterial host cells using techniques such as calcium chloride treatment, electroporation, and others. In one embodiment, cancer proteins are produced in insect cells using, e.g., expression vectors for the transformation of insect cells, and in particular, baculovirus-based expression vectors.
In a preferred embodiment, a cancer protein is produced in yeast cells. Yeast expression systems are well known, and include expression vectors for Saccharomyces cerevisiae, Candida albicans and C. maltosa, Hansenula polymoφha, Kluyveromyces fragilis and K. lactis, Pichia guillerimondii and P. pastoris, Schizosaccharomyces pombe, and Yarrowia lipolytica.
The cancer protein may also be made as a fusion protein, using available techniques. Thus, e.g., for the creation of monoclonal antibodies, if the desired epitope is small, the cancer protein may be fused to a carrier protein to form an immunogen. Alternatively, the cancer protein may be made as a fusion protein to increase expression, or for other reasons. For example, when the cancer protein is a cancer peptide, the nucleic acid encoding the peptide may be linked to other nucleic acid for expression puφoses. Fusion with detection epitope tags can be made, e.g., with FLAG, His6, myc, HA, etc.
In a preferred embodiment, the cancer protein is purified or isolated after expression. Cancer proteins may be isolated or purified in a variety of ways depending on what other components are present in the sample and the requirements for purified product, e.g., natural conformation or denatured. Standard purification methods include ammonium sulfate precipitations, electrophoretic, molecular, immunological, and chromatographic techniques, including ion exchange, hydrophobic, affinity, and reverse-phase HPLC chromatography, and chromatofocusing. For example, the cancer protein may be purified using a standard anti- cancer protein antibody column. Ultrafilfration and diafilfration techniques, in conjunction with protein concentration, are also useful. See, e.g., Walsh (2002) Proteins: Biochemistry and Biotechnology Wiley; Hardin, et al. (eds. 2001) Cloning, Gene Expression and Protein Purification Oxford Univ. Press; Wilson, et al. (eds. 2000) Encyclopedia of Separation Science Academic Press; and Scopes (1993) Protein Purification Springer- Verlag. The degree of purification necessary will vary depending on the use of the cancer protein. In some instances no purification will be necessary.
Once expressed and purified if necessary, the cancer proteins and nucleic acids are useful in a number of applications. They may be used as immunoselection reagents, as vaccine reagents, as screening agents, therapeutic entities, for production of antibodies, as transcription or translation inhibitors, etc. Variants of cancer proteins
Also included within one embodiment of cancer proteins are amino acid variants "of the naturally occurring sequences, as determined herein. Preferably, the variants are preferably greater than about 75% homologous to the wild-type sequence, more preferably greater than about 80%, even more preferably greater than about 85%, and most preferably greater than 90%. In some embodiments the homology will be as high as about 93-95% or 98%. As for nucleic acids, homology in this context means sequence similarity or identity, with identity being preferred. This homology will be determined using standard techniques, as are outlined above for nucleic acid homologies. Cancer proteins of the present invention may be shorter or longer than the wild type amino acid sequences. Thus, in a preferred embodiment, included within the definition of cancer proteins are portions or fragments of the wild type sequences herein. In addition, as outlined above, the cancer nucleic acids of the invention may be used to obtain additional coding regions, and thus additional protein sequence.
In one embodiment, the cancer proteins are derivative or variant cancer proteins as compared to the wild-type sequence. That is, as outlined more fully below, the derivative cancer peptide will often contain at least one amino acid substitution, deletion, or insertion, with amino acid substitutions being particularly preferred. The amino acid substitution, insertion, or deletion may occur at many residue positions within the cancer peptide.
Also included within one embodiment of cancer proteins of the present invention are amino acid sequence variants. These variants typically fall into one or more of three classes: substitutional, insertional, or deletional variants. These variants ordinarily are prepared by site specific mutagenesis of nucleotides in the DNA encoding the cancer protein, using cassette or PCR mutagenesis or other techniques, to produce DNA encoding the variant, and thereafter expressing the DNA in recombinant cell culture as outlined above. However, variant cancer protein fragments having up to about 100-150 residues may be prepared by in vitro synthesis using established techniques. Amino acid sequence variants are characterized by the predetermined nature of the variation, a feature that sets them apart from naturally occurring allelic or interspecies variation of the cancer protein amino acid sequence. The variants typically exhibit a similar qualitative biological activity as a naturally occurring analogue, although variants can also be selected which have modified characteristics. While the site or region for introducing an amino acid sequence variation is often predetermined, the mutation per se need not be predetermined. For example, in order to optimize the performance of a mutation at a given site, random mutagenesis may be conducted at the target codon or region and the expressed cancer variants screened for the optimal combination of desired activity. Techniques for making substitution mutations at predetermined sites in DNA having a known sequence are well known, e.g., M13 primer mutagenesis and PCR mutagenesis. Screening of mutants is often done using assays of cancer protein activities.
Amino acid substitutions are typically of single residues; insertions usually will be on the order of from about 1-20 amino acids, although considerably larger insertions maybe tolerated. Deletions generally range from about 1-20 residues, although in some cases deletions may be much larger.
Substitutions, deletions, insertions, or combination thereof may be used to arrive at a final derivative. Generally these changes are done on a few amino acids to minimize the alteration of the molecule. However, larger changes may be tolerated in certain circumstances. When small alterations in the characteristics of the cancer protein are desired, substitutions are generally made in accordance with the amino acid substitution relationships described.
The variants typically exhibit essentially the same qualitative biological activity and will elicit the same immune response as a naturally-occurring analog, although variants also are selected to modify the characteristics of cancer proteins as needed. Alternatively, the variant may be designed such that a biological activity of the cancer protein is altered. For example, glycosylation sites may be added, altered, or removed.
Substantial changes in function or immunological identity are sometimes made by selecting substitutions that are less conservative than those described above. For example, substitutions may be made which more significantly affect: the structure of the polypeptide backbone in the area of the alteration, for example the alpha-helical or beta-sheet structure; the charge or hydrophobicity of the molecule at the target site; or the bulk of the side chain. Substitutions which generally are expected to produce the greatest changes in the polypeptide's properties are those in which (a) a hydrophilic residue, e.g., serine or threone is substituted for (or by) a hydrophobic residue, e.g., leucine, isoleucine, phenylalanine, valine, or alanine; (b) a cysteine or proline is substituted for (or by) another residue; (c) a residue having an electropositive side chain, e.g., lysine, arginine, or histidine, is substituted for (or by) an electronegative residue, e.g., glutamic or aspartic acid; (d) a residue having a bulky side chain, e.g., phenylalanine, is substituted for (or by) one not having a side chain, e.g., glycine; or (e) a proline residue is incoφorated or substituted, which changes the degree of rotational freedom of the peptidyl bond.
Variants typically exhibit a similar qualitative biological activity and will elicit the same immune response as the naturally-occurring analog, although variants also are selected to modify the characteristics of the skin cancer proteins as needed. Alternatively, the variant may be designed such that the biological activity of the cancer protein is altered. For example, glycosylation sites may be altered or removed.
Covalent modifications of cancer polypeptides are included within the scope of this invention. One type of covalent modification includes reacting targeted amino acid residues of a cancer polypeptide with an organic derivatizing agent that is capable of reacting with selected side chains or the N-or C-terminal residues of a cancer polypeptide. Derivatization with bifunctional agents is useful, for instance, for crosslinking cancer polypeptides to a water- insoluble support matrix or surface for use in a method for purifying anti-cancer polypeptide antibodies or screening assays, as is more fully described below. Commonly used crosslinking agents include, e.g., l,l-bis(diazoacetyl)-2-phenylethane, glutaraldehyde, N- hydroxysuccinimide esters, e.g., esters with 4-azidosalicylic acid, homobifunctional imidoesters, including disuccinimidyl esters such as 3,3'-dithiobis(succinimidylpropionate), bifunctional maleimides such as bis-N-maleimido-l,8-octane and agents such as methyl-3-((p- azidophenyl)dithio)propioimidate.
Other modifications include deamidation of glutaminyl and asparaginyl residues to the corresponding glutamyl and aspartyl residues, respectively, hydroxylation of proline and lysine, phosphorylation of hydroxyl groups of serinyl, threonyl, or tyrosyl residues, methylation of the amino groups of the lysine, arginine, and histidine side chains (e.g., pp. 79-86, Creighton (1992) Proteins: Structure and Molecular Properties Freeman), acetylation of the N-terminal amine, and amidation of a C-terminal carboxyl group.
Another type of covalent modification of the cancer polypeptide included within the scope of this invention comprises altering the native glycosylation pattern of the polypeptide. "Altering the native glycosylation pattern" is intended for puφoses herein to mean deleting one or more carbohydrate moieties found in native sequence cancer polypeptide, and/or adding one or more glycosylation sites that are not present in the native sequence cancer polypeptide. Glycosylation patterns can be altered in many ways. Different cell types to express cancer- associated sequences can result in different glycosylation patterns.
Addition of glycosylation sites to cancer polypeptides may also be accomplished by altering the amino acid sequence thereof. The alteration may be made, e.g., by the addition of, or substitution by, one or more serine or threonine residues to the native sequence cancer polypeptide (for O-linked glycosylation sites). The cancer amino acid sequence may optionally be altered through changes at the DNA level, particularly by mutating the DNA encoding the cancer polypeptide at preselected bases such that codons are generated that will translate into the desired amino acids.
Another means of increasing the number of carbohydrate moieties on the cancer polypeptide is by chemical or enzymatic coupling of glycosides to the polypeptide. See, e.g., WO 87/05330; pp. 259-306 in Aplin and Wriston (1981) CRC Crit. Rev. Biochem. Removal of carbohydrate moieties present on the cancer polypeptide may be accomplished chemically or enzymatically or by mutational substitution of codons encoding for amino acid residues that serve as targets for glycosylation. Chemical deglycosylation techniques are applicable. See, e.g., Sojar and Bahl (1987) Arch. Biochem. Biophys. 259:52-57 and Edge, et al. (1981) Anal. Biochem. 118:131-137. Enzymatic cleavage of carbohydrate moieties on polypeptides can be achieved by the use of a variety of endo-and exo-glycosidases. See, e.g., Thotakura, et al. (1987) Meth. Enzymol. 138:350-359.
Another type of covalent modification of cancer comprises linking the cancer polypeptide to one of a variety of nonproteinaceous polymers, e.g., polyethylene glycol, polypropylene glycol, or polyoxyalkylenes, in the manner set forth in U.S. Patent Nos. 4,640,835; 4,496,689; 4,301,144; 4,670,417; 4,791,192, or 4,179,337. Cancer polypeptides of the present invention may also be modified in a way to form chimeric molecules comprising a cancer polypeptide fused to another heterologous polypeptide or amino acid sequence. In one embodiment, such a chimeric molecule comprises a fusion of a cancer polypeptide with a tag polypeptide which provides an epitope to which an anti-tag antibody can selectively bind. The epitope tag is generally placed at the amino-or carboxyl- terminus of the cancer polypeptide. The presence of such epitope-tagged forms of a cancer polypeptide can be detected using an antibody against the tag polypeptide. Also, provision of the epitope tag enables the cancer polypeptide to be readily purified by affinity purification using an anti-tag antibody or another type of affinity matrix that binds to the epitope tag. In an alternative embodiment, the chimeric molecule may comprise a fusion of a cancer polypeptide with an immunoglobulin or a particular region of an immunoglobulin. For a bivalent form of the chimeric molecule, such a fusion could be to the Fc region of an IgG molecule.
Various tag polypeptides and their respective antibodies are available. Examples"' include poly-histidine (poly-his) or poly-histidine-glycine (poly-his-gly) tags; HIS6 and metal chelation tags, the flu HA tag polypeptide and its antibody 12CA5 (Field, et al. (1988) Mol. Cell. Biol. 8:2159-2165); the c-myc tag and the 8F9, 3C7, 6E10, G4, B7, and 9E10 antibodies thereto (Evan, et al. (1985) Molecular and Cellular Biology 5:3610-3616); and the Heφes Simplex virus glycoprotein D (gD) tag and its antibody (Paborsky, et al. (1990) Protein Engineering 3(6):547-553). Other tag polypeptides include the Flag-peptide (Hopp, et al. (1988) BioTechnology 6:1204-1210); the KT3 epitope peptide (Martin, et al. (1992) Science 255:192-194); tubulin epitope peptide (Skinner, et al. (1991) J. Biol. Chem. 266:15163-15166); and the T7 gene 10 protein peptide tag (Lutz-Freyermuth, et al. (1990) Proc. Natl. Acad. Sci. USA 87:6393-6397). Also included are other cancer proteins of the cancer family, and cancer proteins from other organisms, which are cloned and expressed as outlined below. Thus, probe or degenerate polymerase chain reaction (PCR) primer sequences may be used to find other related cancer proteins from humans or other organisms. Particularly useful probe and/or PCR primer sequences include the unique areas of the cancer nucleic acid sequence. Preferred PCR primers are from about 15-35 nucleotides in length, with from about 20-30 being preferred, and may contain inosine as needed. The conditions for PCR reaction have been well described (e.g., Innis, PCR Protocols, supra).
In addition, cancer proteins can be made that are longer than those encoded by the nucleic acids of the Tables, e.g., by the elucidation of extended sequences, the addition of epitope or purification tags, the addition of other fusion sequences, etc.
Cancer proteins may also be identified as being encoded by cancer nucleic acids. Thus, cancer proteins are encoded by nucleic acids that will hybridize to the sequences of the sequence listings, or their complements, as outlined herein. Antibodies to cancer proteins
In a preferred embodiment, when the cancer protein is to be used to generate antibodies, e.g., for immunotherapy or immunodiagnosis, the cancer protein should share at least one epitope or determinant with the full length protein. By "epitope" or "determinant" herein is typically meant a portion of a protein which will generate and/or bind an antibody or T-cell receptor in the context of MHC. Thus, in most instances, antibodies made to a smaller cancer protein will be able to bind to the full-length protein, particularly linear epitopes. In a preferred embodiment, the epitope is unique; that is, antibodies generated to a unique epitope show little or no cross-reactivity. In a preferred embodiment, the epitope is selected from a protein sequence set out in the tables. Methods of preparing polyclonal antibodies exist (e.g., Coligan, supra; and Harlow and
Lane, supra). Polyclonal antibodies can be raised in a mammal, e.g., by one or more injections of an immunizing agent and, if desired, an adjuvant. Typically, the immunizing agent and/or adjuvant will be injected in the mammal by multiple subcutaneous or intraperitoneal injections. The immunizing agent may include a protein encoded by a nucleic acid of Tables 2A-80 or fragment thereof or a fusion protein thereof. It may be useful to conjugate the immunizing agent to a protein known to be immunogenic in the mammal being immunized. Examples of such immunogenic proteins include but are not limited to keyhole limpet hemocyanin, serum albumin, bovine thyroglobulin, and soybean trypsin inhibitor. Examples of adjuvants which may be employed include Freund's complete adjuvant and MPL-TDM adjuvant (monophosphoryl Lipid A, synthetic trehalose dicorynomycolate). Various immunization protocols may be used. The antibodies may, alternatively, be monoclonal antibodies. Monoclonal antibodies may be prepared using hybridoma methods, such as those described by Kohler and Milstein (1975) Nature 256:495. In a hybridoma method, a mouse, hamster, or other appropriate host animal, is typically immunized with an immunizing agent to elicit lymphocytes that produce or are capable of producing antibodies that will specifically bind to the immunizing agent. Alternatively, the lymphocytes may be immunized in vitro. The immunizing agent will typically include a polypeptide encoded by a nucleic acid of the tables or fragment thereof, or a fusion protein thereof. Generally, either peripheral blood lymphocytes ("PBLs") are used if cells of human origin are desired, or spleen cells or lymph node cells are used if non-human mammalian sources are desired. The lymphocytes are then fused with an immortalized cell line using a suitable fusing agent, such as polyethylene glycol, to form a hybridoma cell (e.g., pp. 59-103 in Goding (1986) Monoclonal Antibodies: Principles and Practice Academic Press). Immortalized cell lines are usually transformed mammalian cells, particularly myeloma cells of rodent, bovine, or human origin. Usually, rat or mouse myeloma cell lines are employed. The hybridoma cells may be cultured in a suitable culture medium that preferably contains one or more substances that inhibit the growth or survival of the unfused, immortalized cells. For example, if the parental cells lack the enzyme hypoxanthine guanine phosphoribosyl transferase (HGPRT or HPRT), the culture medium for the hybridomas typically will include hypoxanthine, aminopterin, and thymidine ("HAT medium"), which substances prevent the growth of HGPRT-deficient cells. In one embodiment, the antibodies are bispecific antibodies. Bispecific antibodies are monoclonal, preferably human or humanized, antibodies that have binding specificities for at least two different antigens or that have binding specificities for two epitopes on the same antigen. In one embodiment, one of the binding specificities is for a protein encoded by a nucleic acid of the tables or a fragment thereof, the other one is for another antigen, and preferably for a cell-surface protein or receptor or receptor subunit, preferably one that is tumor specific. Alternatively, tetramer-type technology may create multivalent reagents. In a preferred embodiment, the antibodies to cancer protein are capable of reducing or eliminating a biological function of a cancer protein, in a naked form or conjugated to an effector moiety, as is described below. That is, the addition of anti-cancer protein antibodies (either polyclonal or preferably monoclonal) to cancer tissue (or cells containing cancer) may reduce or eliminate the cancer. Generally, at least a 25% decrease in activity, growth, size, or the like is preferred, with at least about 50% being particularly prefened and about a 95-100% decrease being especially prefened.
In a prefened embodiment the antibodies to the cancer proteins are humanized antibodies (e.g., Xenerex Biosciences, Medarex, Inc., Abgenix, Inc., Protein Design Labs, Inc.) Humanized forms of non-human (e.g., murine) antibodies are chimeric molecules of immunoglobulins, immunoglobulin chains or fragments thereof (such as Fv, Fab, Fab', F(ab')2 or other antigen-binding subsequences of antibodies) wliich contain minimal sequence derived from non-human immunoglobulin. Humanized antibodies include human immunoglobulins (recipient antibody) in which residues from a complementary determining region (CDR) of the recipient are replaced by residues from a CDR of a non-human species (donor antibody) such as mouse, rat, or rabbit having the desired specificity, affinity, and capacity. In some instances, Fv framework residues of a human immunoglobulin are replaced by conesponding non-human residues. Humanized antibodies may also comprise residues which are found neither in the recipient antibody nor in the imported CDR or framework sequences. In general, a humanized antibody will comprise substantially all of at least one, and typically two, variable domains, in which all or substantially all of the CDR regions conespond to those of a non-human immunoglobulin and all or substantially all of the framework (FR) regions are those of a human immunoglobulin consensus sequence. The humanized antibody optimally also will typically comprise at least a portion of an immunoglobulin constant region (Fc), typically that of a human immunoglobulin (Jones, et al. (1986) Nature 321 :522-525; Riechmann, et al. (1988) Nature 332:323-329; and Presta (1992) Cun. Op. Struct. Biol. 2:593-596). Humanization can be essentially performed following the method of Winter and co-workers (Jones, et al. (1986) Nature 321:522-525; Riechmann, et al. (1988) Nature 332:323-327; Verhoeyen, et al. (1988) Science 239:1534-1536), by substituting rodent CDRs or CDR sequences for conesponding sequences of a human antibody. Accordingly, such humanized antibodies are chimeric antibodies (U.S. Patent No. 4,816,567), wherein substantially less than an intact human variable domain has been substituted by conesponding sequence from a non-human species. Human antibodies can also be produced using phage display libraries (Hoogenboom and Winter (1992) J. Mol. Biol. 227:381-388; Marks, et al. (1991) J. Mol. Biol. 222:581-597) or human monoclonal antibodies (e.g., p. 77, Cole, et al. in Reisfeld and Sell (1985) Monoclonal Antibodies and Cancer Therapy Liss; and Boemer, et al. (1991) J. Immunol. 147:86-95). Similarly, human antibodies can be made by introducing human immunoglobulin loci into transgenic animals, e.g., mice in which the endogenous immunoglobulin genes have been partially or completely inactivated. Upon challenge, human antibody production is observed, which closely resembles that seen in humans in nearly all respects, including gene reanangement, assembly, and antibody repertoire. This approach is described, e.g., in U.S. Patent Nos. 5,545,807; 5,545,806; 5,569,825; 5,625,126; 5,633,425; 5,661,016, and in the following scientific publications: Marks, et al. (1992) Bio/Technology 10:779-783; Lonberg, et al. (1994) Nature 368:856-859; Morrison (1994) Nature 368:812-13; Fishwild, et al. (1996) Nature Biotechnology 14:845-851; Neuberger (1996) Nature Biotechnology 14:826; and Lonberg and Huszar (1995) Intern. Rev. Immunol. 13:65-93. By immunotherapy is meant treatment of cancer with an antibody raised against cancer proteins. As used herein, immunotherapy can be passive or active. Passive immunotherapy as defined herein is the passive transfer of antibody to a recipient (patient). Active immunization is the induction of antibody and/or T-cell responses in a recipient (patient). Induction of an immune response is the result of providing the recipient with an antigen to which antibodies are raised. The antigen may be provided by injecting a polypeptide against which antibodies are desired to be raised into a recipient, or contacting the recipient with a nucleic acid capable of expressing the antigen and under conditions for expression of the antigen, leading to an immune response.
In a prefened embodiment the cancer proteins against which antibodies are raised are secreted proteins as described above. Without being bound by theory, antibodies used for treatment may bind and prevent the secreted protein from binding to its receptor, thereby inactivating the secreted cancer protein, e.g., in autocrine signaling.
In another prefened embodiment, the cancer protein to which antibodies are raised is a transmembrane protein. Without being bound by theory, antibodies used for treatment may bind the extracellular domain of the cancer protein and prevent it from binding to other proteins, such as circulating ligands or cell-associated molecules. The antibody may cause down- regulation of the transmembrane cancer protein. The antibody may be a competitive, non- competitive or uncompetitive inhibitor of protein binding to the extracellular domain of the cancer protein. The antibody may also be an antagonist of the cancer protein. Further, the antibody may prevent activation of the transmembrane cancer protein, or may induce or suppress a particular cellular pathway. In one aspect, when the antibody prevents the binding of other molecules to the cancer protein, the antibody prevents growth of the cell. The antibody may also be used to target or sensitize the cell to cytotoxic agents, including, but not limited to TNF-α, TNF-β, IL-1, ESTF-γ, and IL-2, or chemotherapeutic agents including 5FU, vinblastine, actinomycin D, cisplatin, methotrexate, and the like. In some instances the antibody may belong to a sub-type that activates serum complement when complexed with the transmembrane protein thereby mediating cytotoxicity or antigen-dependent cytotoxicity (ADCC). Thus, cancer may be treated by administering to a patient antibodies directed against the transmembrane cancer protein. Antibody-labeling may activate a co-toxin, localize a toxin payload, target a drug loaded liposome, or otherwise provide means to locally ablate cells.
In another prefened embodiment, the antibody is conjugated to an effector moiety. The effector moiety can be various molecules, including labeling moieties such as radioactive labels or fluorescent labels, or can be a therapeutic moiety. In one aspect the therapeutic moiety is a small molecule that modulates the activity of a cancer protein. In another aspect the therapeutic moiety may modulate the activity of molecules associated with or in close proximity to a cancer protein. The therapeutic moiety may inhibit enzymatic or signaling activity such as protease or collagenase or protein kinase activity associated with cancer, or be an attractant of other cells, such as NK cells. See, e.g., USSN 09/544,494.
In a prefened embodiment, the therapeutic moiety can also be a cytotoxic agent. In this method, targeting the cytotoxic agent to cancer tissue or cells results in a reduction in the number of afflicted cells, thereby reducing symptoms associated with cancer. Cytotoxic agents are numerous and varied and include, but are not limited to, cytotoxic drugs or toxins or active fragments of such toxins. Suitable toxins and their conesponding fragments include diphtheria A chain, exotoxin A chain, ricin A chain, abrin A chain, curcin, crotin, phenomycin, enomycin, saporin, auristatin, and the like. Cytotoxic agents also include radiochemicals made by conjugating radioisotopes to antibodies raised against cancer proteins, or binding of a radionuclide to a chelating agent that has been covalently attached to the antibody. Targeting the therapeutic moiety to transmembrane cancer proteins not only serves to increase the local concentration of therapeutic moiety in the cancer afflicted area, but also serves to reduce deleterious side effects that may be associated with the untargeted therapeutic moiety.
Antibody fragments may be used to target toxin loaded liposomes.
In another prefened embodiment, the cancer protein against which the antibodies are raised is an intracellular protein. In this case, the antibody may be conjugated to a protein which facilitates entry into the cell. In one case, the antibody enters the cell by endocytosis. In another embodiment, a nucleic acid encoding the antibody is administered to the individual or cell. Moreover, wherein the cancer protein can be targeted within a cell, e.g., the nucleus, an antibody thereto may contain a signal for that target localization, e.g., a nuclear localization signal. The cancer antibodies of the invention specifically bind to cancer proteins. By
"specifically bind" herein is meant that the antibodies bind to the protein with a K^ of at least about 0.1 mM, more usually at least about 1 μM, preferably at least about 0.1 μM or better, and most preferably, 0.01 μM or better. Selectivity of binding to the specific target and not to related sequences is often also important. Detection of cancer sequence for diagnostic and therapeutic applications
In one aspect, the RNA expression levels of genes are determined for different cellular states in the cancer phenotype. Expression levels of genes in normal tissue (e.g., not undergoing cancer) and in cancer tissue (and in some cases, for varying severities of cancer that relate to prognosis, as outlined below), or in non-malignant disease are evaluated to provide expression profiles. A gene expression profile of a particular cell state or point of development is essentially a "fingeφrint" of the state of the cell. While two states may have a particular gene similarly expressed, the evaluation of a number of genes simultaneously allows the generation of a gene expression profile that is reflective of the state of the cell. By comparing expression profiles of cells in different states, information regarding which genes are important (including both up- and down-regulation of genes) in each of these states is obtained. Then, diagnosis may be performed or confirmed to determine whether a tissue sample has the gene expression profile of normal or cancerous tissue. This will provide for molecular diagnosis of related conditions.
"Differential expression," or grammatical equivalents as used herein, refers to qualitative or quantitative differences in the temporal and/or cellular gene expression patterns within and among cells and tissue. Thus, a differentially expressed gene can qualitatively have its expression altered, including an activation or inactivation, in, e.g., normal versus cancer tissue. Genes may be turned on or turned off in a particular state, relative to another state thus permitting comparison of two or more states. A qualitatively regulated gene will exhibit an expression pattern within a state or cell type which is detectable by standard techniques. Some genes will be expressed in one state or cell type, but not in both. Alternatively, the difference in expression maybe quantitative, e.g., in that expression is increased or decreased; e.g., gene expression is either upregulated, resulting in an increased amount of transcript, or downregulated, resulting in a decreased amount of transcript. The degree to which expression differs need only be large enough to quantify via standard characterization techniques as outlined below, such as by use of Affymetrix GeneChip™ expression anays. See, Lockhart (1996) Nature Biotechnology 14:1675-1680. Other techniques include, but are not limited to, quantitative reverse transcriptase PCR, northern analysis, and RNase protection. As outlined above, preferably the change in expression (e.g., upregulation or downregulation) is at least about 50%), more preferably at least about 100%, more preferably at least about 150%, more preferably at least about 200%, with from 300 to at least 1000% being especially prefened. Evaluation may be at the gene transcript or the protein level. The amount of gene expression may be monitored using nucleic acid probes to the RNA or DNA equivalent of the gene transcript, and the quantification of gene expression levels, or, alternatively, the final gene product itself (protein) can be monitored, e.g., with antibodies to the cancer protein and standard immunoassays (ELIS As, etc.) or other techniques, including mass spectroscopy assays, 2D gel electrophoresis assays, etc. Proteins conesponding to cancer genes, e.g., those identified as being important in a cancer or disease phenotype, can be evaluated in a cancer diagnostic test. In a prefened embodiment, gene expression monitoring is performed simultaneously on a number of genes. Multiple protein expression monitoring can be performed as well.
In this embodiment, the cancer nucleic acid probes are attached to biochips as outlined herein for the detection and quantification of cancer sequences in a particular cell. The assays are further described below in the example. PCR techniques can be used to provide greater sensitivity.
In a prefened embodiment nucleic acids encoding the cancer protein are detected. Although DNA or RNA encoding the cancer protein may be detected, of particular interest are methods wherein an mRNA encoding a cancer protein is detected. Probes to detect mRNA can be a nucleotide/deoxynucleotide probe that is complementary to and hybridizes with the mRNA and includes, but is not limited to, oligonucleotides, cDNA, or RNA. Probes also should contain a detectable label, as defined herein. In one method the mRNA is detected after immobilizing the nucleic acid to be examined on a solid support such as nylon membranes and hybridizing the probe with the sample. Following washing to remove the non-specifically bound probe, the label is detected. In another method, detection of the mRNA is performed in situ. In this method permeabilized cells or tissue samples are contacted with a detectably labeled nucleic acid probe for sufficient time to allow the probe to hybridize with the target mRNA. Following washing to remove the non-specifically bound probe, the label is detected. For example a digoxygenin labeled riboprobe (RNA probe) that is complementary to the mRNA encoding a cancer protein is detected by binding the digoxygenin with an anti-digoxygenin secondary antibody and developed with nitro blue tetrazolium and 5-bromo-4-chloro-3-indoyl phosphate.
In a prefened embodiment, various proteins from the three classes of proteins as described herein (secreted, transmembrane, or intracellular proteins) are used in diagnostic assays. The cancer proteins, antibodies, nucleic acids, modified proteins, and cells containing cancer sequences are used in diagnostic assays. This can be performed on an individual gene or conesponding polypeptide level. In a prefened embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques to allow monitoring for expression profile genes and/or conesponding polypeptides.
As described and defined herein, cancer proteins, including intracellular, transmembrane, or secreted proteins, find use as markers of cancer, e.g., for prognostic or diagnostic puφoses. Detection of these proteins in putative cancer tissue allows for detection, prognosis, or diagnosis of cancer or similar disease, and for selection of therapeutic strategy. In one embodiment, antibodies are used to detect cancer proteins. A prefened method separates proteins from a sample by electrophoresis on a gel (typically a denaturing and reducing protein gel, but maybe another type of gel, including isoelectric focusing gels and the like). Following separation of proteins, the cancer protein is detected, e.g., by immunoblotting with antibodies raised against the cancer protein.
In another prefened method, antibodies to the cancer protein find use in in situ imaging techniques, e.g., in histology. See, e.g., Asai, et al. (eds. 1993) Methods in Cell Biology: Antibodies in Cell Biology (vol. 37) Academic Press. In this method, cells are contacted with from one to many antibodies to the cancer protein(s). Following washing to remove nonspecific antibody binding, the presence of the antibody or antibodies is detected. In one embodiment the antibody is detected by incubating with a secondary antibody that contains a detectable label. In another method the primary antibody to the cancer protein(s) contains a detectable label, e.g., an enzyme marker that can act on a substrate. In another prefened embodiment each one of multiple primary antibodies contains a distinct and detectable label. This method finds particular use in simultaneous screening for a plurality of cancer proteins. Many other histological imaging techniques are also provided by the invention.
In a prefened embodiment the label is detected in a fluorometer which has the ability to detect and distinguish emissions of different wavelengths. In addition, a fluorescence activated cell sorter (FACS) can be used in the method.
In another prefened embodiment, antibodies find use in diagnosing cancer from blood, serum, plasma, stool, and other samples. Such samples, therefore, are useful as samples to be probed or tested for the presence of cancer proteins. Antibodies can be used to detect a cancer protein by previously described immunoassay techniques including ELISA, immunoblotting (western blotting), immunoprecipitation, BIACORE technology and the like. Conversely, the presence of antibodies may indicate an immune response against an endogenous cancer protein. In a prefened embodiment, in situ hybridization of labeled cancer nucleic acid probes to tissue anays is done. For example, anays of tissue samples, including cancer tissue and/or normal tissue, are made. In situ hybridization (see, e.g., Ausubel, supra) is then performed. When comparing the fingeφrints between an individual and a standard, a diagnosis, a prognosis, or a prediction may be based on the findings. It is further understood that the genes which indicate the diagnosis may differ from those which indicate the prognosis and molecular profiling of the condition of the cells may lead to distinctions between responsive or refractory conditions or may be predictive of outcomes.
In a prefened embodiment, the cancer proteins, antibodies, nucleic acids, modified proteins, and cells containing cancer sequences are used in prognosis assays. As above, gene expression profiles can be generated that conelate to cancer, clinical, pathological, or other information, in terms of long term prognosis. Again, this may be done on either a protein or gene level, with the use of genes being prefened. Single or multiple genes may be useful in various combinations. As above, cancer probes may be attached to biochips for the detection and quantification of cancer sequences in a tissue or patient. The assays proceed as outlined above for diagnosis. PCR method may provide more sensitive and accurate quantification. Assays for therapeutic compounds
In a prefened embodiment, the proteins, nucleic acids, and antibodies as described herein are used in drug screening assays. The cancer proteins, antibodies, nucleic acids, modified proteins, and cells containing cancer sequences are used in drug screening assays or by evaluating the effect of drug candidates on a "gene expression profile" or expression profile of polypeptides. In a prefened embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques, to allow monitoring for expression profile genes after treatment with a candidate agent (e.g., Zlokarnik, et al. (1998) Science 279:84-88; Heid (1996) Genome Res. 6:986-994. In a prefened embodiment, the cancer proteins, antibodies, nucleic acids, modified proteins and cells containing the native or modified cancer proteins are used in screening assays. That is, the present invention provides novel methods for screening for compositions which modulate the cancer phenotype or an identified physiological function of a cancer protein. As above, this can be done on an individual gene level or by evaluating the effect of drug candidates on a "gene expression profile". In a prefened embodiment, the expression profiles are used, preferably in conjunction with high throughput screening techniques, to allow monitoring for expression profile genes after treatment with a candidate agent, see Zlokarnik, supra.
Having identified the differentially expressed genes herein, a variety of assays may be performed. In a prefened embodiment, assays may be run on an individual gene or protein level. That is, having identified a particular gene as up regulated in cancer, test compounds can be screened for the ability to modulate gene expression or for binding to the cancer protein. "Modulation" thus includes both an increase and a decrease in gene expression. The prefened amount of modulation will depend on the original change of the gene expression in normal versus tissue undergoing cancer, with changes of at least 10%, preferably 50%, more preferably 100-300%, and in some embodiments 300-1000% or greater. Thus, if a gene exhibits a 4-fold increase in cancer tissue compared to normal tissue, a decrease of about four-fold is often desired; similarly, a 10-fold decrease in cancer tissue compared to normal tissue often provides a target value of a 10-fold increase in expression to be induced by the test compound. The amount of gene expression may be monitored using nucleic acid probes and the quantification of gene expression levels, or, alternatively, the gene product itself can be monitored, e.g., through the use of antibodies to the cancer protein and standard immunoassays. Proteomics and separation techniques may also allow quantification of expression.
In a prefened embodiment, gene expression or protein monitoring of a number of entities, e.g., an expression profile, is monitored simultaneously. Such profiles will typically involve a plurality of those entities described herein.
In this embodiment, the cancer nucleic acid probes are attached to biochips as outlined herein for the detection and quantification of cancer sequences in a particular cell. Alternatively, PCR may be used. Thus, a series, e.g., of microtiter plate, may be used with dispensed primers in desired wells. A PCR reaction can then be performed and analyzed for each well.
Modulators of cancer
Expression monitoring can be performed to identify compounds that modify the expression of one or more cancer-associated sequences, e.g., a polynucleotide sequence set out in the tables. Generally, in a prefened embodiment, a test modulator is added to the cells prior to analysis. Moreover, screens are also provided to identify agents that modulate cancer, modulate cancer proteins, bind to a cancer protein, or interfere with the binding of a cancer protein and an antibody or other binding partner.
The term "test compound" or "drug candidate" or "modulator" or grammatical equivalents as used herein describes a molecule, e.g., protein, oligopeptide, small organic molecule, polysaccharide, polynucleotide, etc., to be tested for the capacity to directly or indirectly alter the cancer phenotype or the expression of a cancer sequence, e.g., a nucleic acid or protein sequence. In prefened embodiments, modulators alter expression profiles, or expression profile nucleic acids or proteins provided herein. In one embodiment, the modulator suppresses a cancer phenotype, e.g., to a normal or non-malignant tissue fingeφrint. In another embodiment, a modulator induced a cancer phenotype. Generally, a plurality of assay mixtures are run in parallel with different agent concentrations to obtain a differential response to the various concentrations. Typically, one of these concentrations serves as a negative control, e.g., at zero concentration or below the level of detection. Drug candidates encompass numerous chemical classes, though typically they are organic molecules, preferably small organic compounds having a molecular weight of more than 100 and less than about 2,500 daltons. Prefened small molecules are less than 2000, or less than 1500, or less than 1000, or less than 500 D. Candidate agents comprise functional groups necessary for structural interaction with proteins, particularly hydrogen bonding, and typically include at least an amine, carbonyl, hydroxyl or carboxyl group, preferably at least two of the functional chemical groups. The candidate agents often comprise cyclical carbon or heterocyclic structures and/or aromatic or polyaromatic structures substituted with one or more of the above functional groups. Candidate agents are also found among biomolecules including peptides, saccharides, fatty acids, steroids, purines, pyrimidines, derivatives, structural analogs, or combinations thereof. Particularly prefened are peptides.
In one aspect, a modulator will neutralize the effect of a cancer protein. By "neutralize" is meant that activity of a protein is inhibited or blocked and the consequent effect on the cell. In certain embodiments, combinatorial libraries of potential modulators will be screened for an ability to bind to a cancer polypeptide or to modulate activity. Conventionally, new chemical entities with useful properties are generated by identifying a chemical compound (called a "lead compound") with some desirable property or activity, e.g., inhibiting activity, creating variants of the lead compound, and evaluating the property and activity of those variant compounds. Often, high throughput screening (HTS) methods are employed for such an analysis. See, e.g., Janzen (2002) High Throughput Screening: Methods and Protocols Humana; Devlin (ed. 1997) High Throughput Screening: The Discovery of Bioactive Substances Dekker; and Mei and Czarnik (eds. 2002) Integrated Drug Discovery Techniques Dekker.
In one prefened embodiment, high throughput screening methods involve providing a library containing a large number of potential therapeutic compounds (candidate compounds). Such "combinatorial chemical libraries" are then screened in one or more assays to identify those library members (particular chemical species or subclasses) that display a desired characteristic activity. The compounds thus identified can serve as conventional "lead compounds" or can themselves be used as potential or actual therapeutics.
A combinatorial chemical library is a collection of diverse chemical compounds generated by either chemical synthesis or biological synthesis by combining a number of chemical "building blocks" such as reagents. For example, a linear combinatorial chemical library, such as a polypeptide (e.g., mutein) library, is formed by combining a set of chemical building blocks called amino acids in every possible way for a given compound length (e.g., the number of amino acids in a polypeptide compound). Millions of chemical compounds can be synthesized through such combinatorial mixing of chemical building blocks (Gallop, et al. (1994) J. Med. Chem. 37:1233-1251).
Preparation and screening of combinatorial chemical libraries is well known. Such combinatorial chemical libraries include, but are not limited to, peptide libraries (see, e.g., U.S. Patent No. 5,010,175, Furka (1991) Pept. Prot. Res. 37:487-493, Houghton, et al. (1991) Nature 354:84-88), peptoids (PCT Publication No WO 91/19735), encoded peptides (PCT Publication WO 93/20242), random bio-oligomers (PCT Publication WO 92/00091), benzodiazepines (U.S. Pat. No. 5,288,514), diversomers such as hydantoins, benzodiazepines and dipeptides (Hobbs, et al. (1993) Proc. Natl. Acad. Sci. USA 90:6909-6913, vinylogous polypeptides (Hagihara, et al. (1992) J. Amer. Chem. Soc. 114:6568-570), nonpeptidal peptidomimetics with a Beta-D- Glucose scaffolding (Hirschmann, et al. (1992) J. Amer. Chem. Soc. 114:9217-9218), analogous organic syntheses of small compound libraries (Chen, et al. (1994) J. Amer. Chem. Soc. 116:2661-662), oligocarbamates (Cho, et al. (1993) Science 261:1303-1305), and/or peptidyl phosphonates (Campbell, et al. (1994) J. Org. Chem. 59:658). See, generally, Gordon, et al. (1994) J. Med. Chem. 37:1385-1401, nucleic acid libraries (see, e.g., Sfratagene, Coφ.), peptide nucleic acid libraries (see, e.g., U.S. Patent 5,539,083), antibody libraries (see, e.g., Vaughn, et al. (1996) Nature Biotechnology 14(3):309-314, and PCT/US96/10287), carbohydrate libraries (see, e.g., Liang, et al. (1996) Science 274:1520-1522, and U.S. Patent No. 5,593,853), and small organic molecule libraries (see, e.g., benzodiazepines, page 33 Baum (Jan 18, 1993) C&EN; isoprenoids, U.S. Patent No. 5,569,588; thiazolidinones and metathiazanones, U.S. Patent No. 5,549,974; pynolidines, U.S. Patent Nos. 5,525,735 and 5,519,134; moφholino compounds, U.S. Patent No. 5,506,337; benzodiazepines, U.S. Patent No. 5,288,514; and the like).
Devices for the preparation of combinatorial libraries are commercially available (see, e.g., 357 MPS, 390 MPS, Advanced Chem Tech, Louisville KY, Symphony, Rainin, Wobum, MA, 433A Applied Biosystems, Foster City, CA, 9050 Plus, Millipore, Bedford, MA).
A number of well known robotic systems have also been developed for solution phase chemistries. These systems include automated workstations like the automated synthesis apparatus developed by Takeda Chemical Industries, LTD. (Osaka, Japan) and many robotic systems utilizing robotic arms (Zymate II, Zymark Coφoration, Hopkinton, Mass.; Orca,
Hewlett-Packard, Palo Alto, Calif.), which mimic manual synthetic operations performed by a chemist. The above devices are suitable for use with the present invention. The nature and implementation of modifications to these devices (if any) so that they can operate as discussed herein will be apparent. In addition, numerous combinatorial libraries are themselves commercially available (see, e.g., ComGenex, Princeton, N.J., Asinex, Moscow, Ru, Tripos, Inc., St. Louis, MO, ChemStar, Ltd, Moscow, RU, 3D Pharmaceuticals, Exton, PA, Martek Biosciences, Columbia, MD, etc.).
The assays to identify modulators are amenable to high throughput screening. Prefened assays thus detect enhancement or inhibition of cancer gene transcription, inhibition, or enhancement of polypeptide expression, and inhibition or enhancement of polypeptide activity. High throughput assays for the presence, absence, quantification, or other properties of particular nucleic acids or protein products are well known. Similarly, binding assays and reporter gene assays are similarly well known. Thus, e.g., U.S. Patent No. 5,559,410 discloses high throughput screening methods for proteins, U.S. Patent No. 5,585,639 discloses high throughput screening methods for nucleic acid binding (e.g., in anays), while U.S. Patent Nos. 5,576,220 and 5,541,061 disclose high throughput methods of screening for ligand/antibody binding.
In addition, high throughput screening systems are commercially available (see, e.g., Zymark Coφ., Hopkinton, MA; Air Technical Industries, Mentor, OH; Beckman Instruments, Inc. Fullerton, CA; Precision Systems, Inc., Natick, MA, etc.). These systems typically automate entire procedures, including sample and reagent pipetting, liquid dispensing, timed incubations, and final readings of the microplate in detector(s) appropriate for the assay. These configurable systems provide high throughput and rapid start up as well as a high degree of flexibility and customization. The manufacturers of such systems provide detailed protocols for various high throughput systems. Thus, e.g., Zymark Coφ. provides technical bulletins describing screening systems for detecting the modulation of gene transcription, ligand binding, and the like.
In one embodiment, modulators are proteins, often naturally occurring proteins or fragments of naturally occurring proteins. Thus, e.g., cellular extracts containing proteins, or random or directed digests of proteinaceous cellular extracts, may be used. In this way libraries of proteins may be made for screening in the methods of the invention. Particularly prefened in this embodiment are libraries of bacterial, fungal, viral, and mammalian proteins, with the latter being prefened, and human proteins being especially prefened. Particularly Useful test compound will be directed to the class of proteins to which the target belongs, e.g., substrates for enzymes or ligands and receptors.
In a prefened embodiment, modulators are peptides of from about 5-30 amino acids, with from about 5-20 amino acids being prefened, and from about 7-15 being particularly prefened. The peptides may be digests of naturally occurring proteins, random peptides, or "biased" random peptides. By "randomized" or grammatical equivalents herein is meant that each nucleic acid and peptide consists of essentially random nucleotides and amino acids, respectively. Since generally these random peptides (or nucleic acids, discussed below) are chemically synthesized, they may incoφorate a nucleotide or amino acid at any position. The synthetic process can be designed to generate randomized proteins or nucleic acids, to allow the formation of all or most of the possible combinations over the length of the sequence, thus forming a library of randomized candidate bioactive proteinaceous agents.
In one embodiment, the library is fully randomized, with no sequence preferences or constants at any position. In a prefened embodiment, the library is biased. That is, some positions within the sequence are either held constant, or are selected from a limited number of possibilities. For example, in a prefened embodiment, the nucleotides or amino acid residues are randomized within a defined class, e.g., of hydrophobic amino acids, hydrophilic residues, sterically biased (either small or large) residues, towards the creation of nucleic acid binding domains, the creation of cysteines, for cross-linking, prolines for SH-3 domains, serines, threonines, tyrosines, or histidines for phosphorylation sites, etc., or to purines, etc. Modulators of cancer can also be nucleic acids, as defined above. As described above generally for proteins, nucleic acid modulating agents may be naturally occurring nucleic acids, random nucleic acids, or "biased" random nucleic acids. For example, digests of prokaryotic or eukaryotic genomes maybe used as is outlined above for proteins.
In a prefened embodiment, the candidate compounds are organic chemical moieties, a wide variety of which are available in the literature.
After the candidate agent has been added and the cells allowed to incubate for some period of time, the sample containing a target sequence to be analyzed is added to the biochip. If required, the target sequence is prepared using known techniques. For example, the sample may be treated to lyse the cells, using known lysis buffers, electroporation, etc., with purification and/or amplification such as PCR performed as appropriate. For example, an in vitro transcription with labels covalently attached to the nucleotides is performed. Generally, the nucleic acids are labeled with biotin-FITC or PE, or with cy3 or cy5.
In a prefened embodiment, the target sequence is labeled with, e.g., a fluorescent, a chemiluminescent, a chemical, or a radioactive signal, to provide a means of detecting the target sequence's specific binding to a probe. The label also can be an enzyme, such as, alkaline phosphatase or horseradish peroxidase, which when provided with an appropriate substrate produces a product that can be detected. Alternatively, the label can be a labeled compound or small molecule, such as an enzyme inhibitor, that binds but is not catalyzed or altered by the enzyme. The label also can be a moiety or compound, such as, an epitope tag or biotin which specifically binds to streptavidin. For the example of biotin, the streptavidin is labeled as described above, thereby, providing a detectable signal for the bound target sequence. Unbound labeled streptavidin is typically removed prior to analysis.
These assays can be direct hybridization assays or can comprise "sandwich assays", which include the use of multiple probes, as is generally outlined in U.S. Patent Nos. 5,681,702, 5,597,909, 5,545,730, 5,594,117, 5,591,584, 5,571,670, 5,580,731, 5,571,670, 5,591,584,
5,624,802, 5,635,352, 5,594,118, 5,359,100, 5,124,246, and 5,681,697, all of which are hereby incoφorated by reference. In this embodiment, in general, the target nucleic acid is prepared as outlined above, and then added to the biochip comprising a plurality of nucleic acid probes, under conditions that allow the formation of a hybridization complex. A variety of hybridization conditions may be used in the present invention, including high, moderate, and low stringency conditions as outlined above. The assays are generally run under stringency conditions which allows formation of the label probe hybridization complex only in the presence of target. Stringency can be controlled by altering a step parameter that is a thermodynamic variable, including, but not limited to, temperature, formamide concentration, salt concentration, chaofropic salt concentration, pH, organic solvent concentration, etc.
These parameters may also be used to confrol non-specific binding, as is generally outlined in U.S. Patent No. 5,681,697. Thus it may be desirable to perform certain steps at higher stringency conditions to reduce non-specific binding.
The reactions outlined herein may be accomplished in a variety of ways. Components of the reaction may be added simultaneously, or sequentially, in different orders, with prefened embodiments outlined below. In addition, the reaction may include a variety of other reagents. These include salts, buffers, neutral proteins, e.g., albumin, detergents, etc. which may be used to facilitate optimal hybridization and detection, and/or reduce non-specific or background interactions. Reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., may also be used as appropriate, depending on the sample preparation methods and purity of the target. The assay data are analyzed to determine the expression levels, and changes in expression levels as between states of individual genes, forming a gene expression profile.
Screens are performed to identify modulators of the cancer phenotype. In one embodiment, screening is performed to identify modulators that can induce or suppress a particular expression profile, thus preferably generating the associated phenotype. In another embodiment, e.g., for diagnostic applications, having identified differentially expressed genes important in a particular state, screens can be performed to identify modulators that alter expression of individual genes. In an another embodiment, screening is performed to identify modulators that alter a biological function of the expression product of a differentially expressed gene. Again, having identified the importance of a gene in a particular state, screens are performed to identify agents that bind and/or modulate the biological activity of the gene product.
In addition, screens can be done for genes that are induced in response to a candidate agent or treatment process. After identifying a modulator based upon its ability to suppress a cancer expression pattern leading to a normal expression pattern (or its converse), or to modulate a single cancer gene expression profile so as to mimic the expression of the gene from normal tissue, a screen as described above can be performed to identify genes that are specifically modulated in response to the agent. Comparing expression profiles between normal tissue and agent treated cancer tissue reveals genes that are not expressed in normal tissue or cancer tissue, but are expressed in agent treated tissue. These agent-specific sequences can be identified and used by methods described herein for cancer genes or proteins. In particular, these sequences and the proteins they encode find use in marking or identifying agent treated cells. In addition, antibodies can be raised against the agent induced proteins and used to target novel therapeutics, e.g., toxin loaded liposomes, to the treated cancer tissue sample.
Thus, in one embodiment, a test compound is administered to a population of cancer cells that have an associated cancer expression profile. By "administration" or "contacting" herein is meant that the candidate agent is added to the cells in such a manner as to allow the agent to act upon the cell, whether by uptake and intracellular action, or by action at the cell surface. In some embodiments, nucleic acid encoding a proteinaceous candidate agent (e.g., a peptide) may be put into a viral construct such as an adenoviral or retroviral construct, and added to the cell, such that expression of the peptide agent is accomplished, e.g., PCT US97/01019. Regulatable gene therapy systems can also be used. Once a test compound has been administered to the cells, the cells can be washed if desired and are allowed to incubate under preferably physiological conditions for some period of time. The cells are then harvested and a new gene expression profile is generated, as outlined herein.
Thus, e.g., cancer or non-malignant tissue may be screened for agents that modulate, e.g., induce or suppress a cancer phenotype. A change in at least one gene, preferably many, of the expression profile indicates that the agent has an effect on cancer activity. By defining such a signature for the cancer phenotype, screens for new drugs that alter the phenotype can be devised. With this approach, the drug target need not be known and need not be represented in the original expression screening platform, nor does the level of transcript for the target protein need to change.
In a prefened embodiment, as outlined above, screens may be done on individual genes and gene products (proteins). That is, having identified a particular differentially expressed gene as important in a particular state, screening of modulators of either the expression of the gene or the gene product itself can be done. The gene products of differentially expressed genes are sometimes refened to herein as "cancer proteins" or a "cancer modulatory protein". The cancer modulatory protein may be a fragment, or alternatively, be the full length protein to the fragment encoded by the nucleic acids of the Tables. Preferably, the cancer modulatory protein is a fragment. In a prefened embodiment, the cancer amino acid sequence which is used to determine sequence identity or similarity is encoded by a nucleic acid of the Tables. In another embodiment, the sequences are naturally occurring allelic variants of a protein encoded by a nucleic acid of the Tables. In another embodiment, the sequences are sequence variants as further described herein.
Preferably, the cancer modulatory protein is a fragment of about 14-24 amino acids long. More preferably the fragment is a soluble fragment. Preferably, the fragment includes a non-fransmembrane region. In a prefened embodiment, the fragment has an N-terminal Cys to aid in solubility. In one embodiment, the C-terminus of the fragment is kept as a free acid and the N-terminus is a free amine to aid in coupling, e.g., to cysteine. In one embodiment the cancer proteins are conjugated to an immunogenic agent as discussed herein. In one embodiment the cancer protein is conjugated to BSA.
Measurements of cancer polypeptide activity, or of cancer or the cancer phenotype can be performed using a variety of assays. For example, the effects of the test compounds upon the function of the cancer polypeptides can be measured by examining parameters described above. A suitable physiological change that affects activity can be used to assess the influence of a test compound on the polypeptides of this invention. When the functional consequences are determined using intact cells or animals, one can also measure a variety of effects such as, in the case of cancer associated with tumors, tumor growth, tumor metastasis, neovascularization, hormone release, transcriptional changes to both known and uncharacterized genetic markers (e.g., northern blots), changes in cell metabolism such as cell growth or pH changes, and changes in intracellular second messengers such as cGMP. In the assays of the invention, mammalian cancer polypeptide is typically used, e.g., mouse, preferably human.
Assays to identify compounds with modulating activity can be performed in vitro. For example, a cancer polypeptide is first contacted with a potential modulator and incubated for a suitable amount of time, e.g., from 0.5-48 hours. In one embodiment, the cancer polypeptide levels are determined in vitro by measuring the level of protein or mRNA. The level of protein is typically measured using immunoassays such as western blotting, ELISA, and the like with an antibody that selectively binds to the cancer polypeptide or a fragment thereof. For measurement of mRNA, amplification, e.g., using PCR, LCR, or hybridization assays, e.g., northern hybridization, RNAse protection, dot blotting, are prefened. The level of protein or mRNA is typically detected using directly or indirectly labeled detection agents, e.g., fluorescently or radioactively labeled nucleic acids, radioactively or enzymatically labeled antibodies, and the like, as described herein. Alternatively, a reporter gene system can be devised using a cancer protein promoter operably linked to a reporter gene such as luciferase, green fluorescent protein, CAT, or β-gal. The reporter construct is typically transfected into a cell. After treatment with a potential modulator, the amount of reporter gene transcription, translation, or activity is measured according to standard techniques. In a prefened embodiment, as outlined above, screens may be done on individual genes and gene products (proteins). That is, having identified a particular differentially expressed gene as important in a particular state, screening of modulators of the expression of the gene or the gene product itself can be done. The gene products of differentially expressed genes are sometimes refened to herein as "cancer proteins." The cancer protein may be a fragment, or alternatively, the full length protein to a fragment shown herein.
In one embodiment, screening for modulators of expression of specific genes is performed. Typically, the expression of only one or a few genes are evaluated. In another embodiment, screens are designed to first find compounds that bind to differentially expressed proteins. These compounds are then evaluated for the ability to modulate differentially expressed activity. Moreover, once initial candidate compounds are identified, variants can be further screened to better evaluate structure activity relationships. In a prefened embodiment, binding assays are done. In general, purified or isolated gene product is used; that is, the gene products of one or more differentially expressed nucleic acids are made. For example, antibodies are generated to the protein gene products, and standard immunoassays are run to determine the amount of protein present. Alternatively, cells comprising the cancer proteins can be used in the assays. Thus, in a prefened embodiment, the methods comprise combining a cancer protein and a candidate compound, and determining the binding of the compound to the cancer protein. Prefened embodiments utilize the human cancer protein, although other mammalian proteins may also be used, e.g., for the development of animal models of human disease. In some embodiments, as outlined herein, variant or derivative cancer proteins may be used. Generally, in a prefened embodiment of the methods herein, the cancer protein or the candidate agent is non-diffusably bound to an insoluble support, preferably having isolated sample receiving areas (e.g., a microtiter plate, an anay, etc.). The insoluble supports may be made of a composition to which the compositions can be bound, is readily separated from soluble material, and is otherwise compatible with the overall method of screening. The surface of such supports may be solid or porous and of a convenient shape. Examples of suitable insoluble supports include microtiter plates, anays, membranes, and beads. These are typically made of glass, plastic (e.g., polystyrene), polysaccharides, nylon or nitrocellulose, teflon™, etc. Microtiter plates and anays are especially convenient because a large number of assays can be carried out simultaneously, using small amounts of reagents and samples. The particular manner of binding of the composition is typically not crucial so long as it is compatible with the reagents and overall methods of the invention, maintains the activity of the composition, and is nondiffusable. Prefened methods of binding include the use of antibodies (which do not sterically block either the ligand binding site or activation sequence when the protein is bound to the support), direct binding to "sticky" or ionic supports, chemical crosslinking, the synthesis of the protein or agent on the surface, etc. Following binding of the protein or agent, excess unbound material is removed by washing. The sample receiving areas may then be blocked through incubation with bovine serum albumin (BSA), casein, or other innocuous protein or other moiety.
In a prefened embodiment, the cancer protein is bound to the support, and a test compound is added to the assay. Alternatively, the candidate agent is bound to the support and the cancer protein is added. Novel binding agents include specific antibodies, non-natural binding agents identified in screens of chemical libraries, peptide analogs, etc. Of particular interest are screening assays for agents that have a low toxicity for human cells. A wide variety of assays may be used for this puφose, including labeled in vitro protein-protein binding assays, electrophoretic mobility shift assays, immunoassays for protein binding, functional assays (phosphorylation assays, etc.), and the like. The determination of the binding of the test modulating compound to the cancer protein may be done in a number of ways. In a prefened embodiment, the compound is labeled, and binding determined directly, e.g., by attaching all or a portion of the cancer protein to a solid support, adding a labeled candidate agent (e.g., a fluorescent label), washing off excess reagent, and determimng whether the label is present on the solid support. Various blocking and washing steps may be utilized as appropriate.
In some embodiments, only one of the components is labeled, e.g., the proteins (or proteinaceous candidate compounds) can be labeled. Alternatively, more than one component can be labeled with different labels, e.g., 125j for fl^ proteins and a fluorophor for the compound. Proximity reagents, e.g., quenching or energy transfer reagents are also useful. In one embodiment, the binding of the test compound is determined by competitive binding assay. The competitor may be a binding moiety known to bind to the target molecule (e.g., a cancer protein), such as an antibody, peptide, binding partner, ligand, etc. Under certain circumstances, there may be competitive binding between the compound and the binding moiety, with the binding moiety displacing the compound. In one embodiment, the test compound is labeled. Either the compound, or the competitor, or both, is added first to the protein for a time sufficient to allow binding, if present. Incubations may be performed at a temperature which facilitates optimal activity, typically between about 4-40° C. Incubation periods are typically optimized, e.g., to facilitate rapid high throughput screening. Typically between 0.1-1 hour will be sufficient. Excess reagent is generally removed or washed away. The second component is then added, and the presence or absence of the labeled component is followed, to indicate binding. In a prefened embodiment, the competitor is added first, followed by a test compound.
Displacement of the competitor is an indication that the test compound is binding to the cancer protein and thus is capable of binding to, and potentially modulating, the activity of the cancer protein. In this embodiment, either component can be labeled. Thus, e.g., if the competitor is labeled, the presence of label in the wash solution indicates displacement by the agent. Alternatively, if the test compound is labeled, the presence of the label on the support indicates displacement.
In an alternative embodiment, the test compound is added first, with incubation and washing, followed by the competitor. The absence of binding by the competitor may indicate that the test compound is bound to the cancer protein with a higher affinity. Thus, if the test compound is labeled, the presence of the label on the support, coupled with a lack of competitor binding, may indicate that the test compound is capable of binding to the cancer protein.
In a prefened embodiment, the methods comprise differential screening to identity agents that are capable of modulating the activity of the cancer proteins. In one embodiment, the methods comprise combining a cancer protein and a competitor in a first sample. A second sample comprises a test compound, a cancer protein, and a competitor. The binding of the competitor is determined for both samples, and a change, or difference in binding between the two samples indicates the presence of an agent capable of binding to the cancer protein arid potentially modulating its activity. That is, if the binding of the competitor is different in the second sample relative to the first sample, the agent is capable of binding to the cancer protein. Alternatively, differential screening is used to identify drug candidates that bind to the native cancer protein, but cannot bind to modified cancer proteins. The structure of the cancer protein may be modeled, and used in rational drug design to synthesize agents that interact with that site. Drug candidates that affect the activity of a cancer protein are also identified by screening drugs for the ability to either enhance or reduce the activity of the protein. Positive controls and negative controls may be used in the assays. Preferably confrol and test samples are performed in at least triplicate to obtain statistically significant results. Incubation of all samples is for a time sufficient for the binding of the agent to the protein. Following incubation, samples are washed free of non-specifically bound material and the amount of bound, generally labeled agent determined. For example, where a radiolabel is employed, the samples may be counted in a scintillation counter to determine the amount of bound compound. A variety of other reagents may be included in the screening assays. These include reagents like salts, neutral proteins, e.g., albumin, detergents, etc., which may be used to facilitate optimal protein-protein binding and/or reduce non-specific or background interactions. Also reagents that otherwise improve the efficiency of the assay, such as protease inhibitors, nuclease inhibitors, anti-microbial agents, etc., maybe used. The mixture of components may be added in an order that provides for the requisite binding.
In a prefened embodiment, the invention provides methods for screening for a compound capable of modulating the activity of a cancer protein. The methods comprise adding a test compound, as defined above, to a cell comprising cancer proteins. Prefened cell types include almost any cell. The cells contain a recombinant nucleic acid that encodes a cancer protein. In a prefened embodiment, a library of candidate agents are tested on a plurality of cells.
In one aspect, the assays are evaluated in the presence or absence or previous or subsequent exposure of physiological signals, e.g., hormones, antibodies, peptides, antigens, cytokines, growth factors, action potentials, pharmacological agents including chemotherapeutics, radiation, carcinogenics, or other cells (e.g., cell-cell contacts). In another example, the determinations are determined at different stages of the cell cycle process.
In this way, compounds that modulate cancer agents are identified. Compounds with pharmacological activity are able to enhance or interfere with the activity of the cancer protein. Once identified, similar structures are evaluated to identify critical structural feature of the compound.
In one embodiment, a method of inhibiting cancer cell division is provided. The method comprises administration of a cancer inhibitor. In another embodiment, a method of inhibiting cancer is provided. The method may comprise adminisfration of a cancer inhibitor. In a further embodiment, methods of treating cells or individuals with cancer are provided, e.g., comprising administration of a cancer inhibitor.
In one embodiment, a cancer inhibitor is an antibody as discussed above. In another embodiment, the cancer inhibitor is an antisense molecule. A variety of cell growth, proliferation, viability, and metastasis assays are available, as described below. Soft agar growth or colony formation in suspension
Normal cells require a solid substrate to attach and grow. When the cells are transformed, they lose this phenotype and grow detached from the substrate. For example, transformed cells can grow in stined suspension culture or suspended in semi-solid media, such as semi-solid or soft agar. The transformed cells, when transfected with tumor suppressor genes, regenerate normal phenotype and require a solid substrate to attach and grow. Soft agar growth or colony formation in suspension assays can be used to identify modulators of cancer sequences, which when expressed in host cells, inhibit abnormal cellular proliferation and transformation. A therapeutic compound would reduce or eliminate the host cells' ability to grow in stined suspension culture or suspended in semi-solid media, such as semi-solid or soft. Techniques for soft agar growth or colony formation in suspension assays are described, e.g., in Freshney (1998) Culture of Animal Cells: A Manual of Basic Technique (3d ed.) Wiley- Liss; Freshney (2000) Culture of Animal Cells: A Manual of Basic Technique (4th ed.) Wiley- Liss; and Garkavtsev, et al. (1996) Nature Genet. 14:415-20. Contact inhibition and density limitation of growth
Normal cells typically grow in a flat and organized pattern in a petri dish until they touch other cells. When the cells touch one another, they are contact inhibited and stop growing. When cells are transformed, however, the cells are not contact inhibited and continue to grow to high densities in disorganized foci. Thus, the transformed cells grow to a higher saturation density than normal cells. This can be detected moφhologically by the formation of a disoriented monolayer of cells or rounded cells in foci within the regular pattern of normal sunounding cells. Alternatively, labeling index with (3H)-thymidine at saturation density can be used to measure density limitation of growth. See Freshney (2000), supra. The transformed cells, when transfected with tumor suppressor genes, regenerate a normal phenotype and become contact inhibited and would grow to a lower density.
In this assay, labeling index with (3H)-thymidine at saturation density is a prefened method of measuring density limitation of growth. Transformed host cells are transfected with a cancer-associated sequence and are grown for 24 hours at saturation density in non-limiting medium conditions. The percentage of cells labeling with (3H)-thymidine is determined autoradiographically. See, Freshney (1998), supra. Growth factor or serum dependence
Transformed cells typically have a lower serum dependence than their normal counteφarts (see, e.g., Temin (1966) J. Natl. Cancer Insti. 37:167-175; Eagle, et al.(1970) J.
Exp. Med. 131:836-879); Freshney, supra. This is in part due to release of various growth factors by the transformed cells. Growth factor or serum dependence of fransformed host cells can be compared with that of control.
Tumor specific markers levels
Tumor cells release an increased amount of certain factors (hereinafter "tumor specific markers") than their normal counteφarts. For example, plasminogen activator (PA) is released from human glioma at a higher level than from normal brain cells (see, e.g., Gullino
"Angiogenesis, tumor vascularization, and potential interference with tumor growth" pp. 178-
184 in Mihich (ed. 1985) Biological Responses in Cancer Plenum. Similarly, tumor angiogenesis factor (TAF) is released at a higher level in tumor cells than their normal counteφarts. See, e.g., Folkman (1992) Sem. Cancer Biol. 3:89-96. Various techniques which measure the release of these factors are described in Freshney
(1998), supra. Also, see, Unkeless, et al. (1974) J. Biol. Chem. 249:4295-4305; Strickland and
Beers (1976) J. Biol. Chem. 251:5694-5702; Whur, et al. (1980) Br. J. Cancer 42:305-312;
Gullino "Angiogenesis, tumor vascularization, and potential interference with tumor growth" pp. 178-184 in Mihich (ed. 1985) Biological Responses in Cancer Plenum; Freshney (1985) Anticancer Res. 5 : 111 - 130.
Invasiveness into Matrigel
The degree of invasiveness into Matrigel or some other extracellular matrix constituent can be used as an assay to identify compounds that modulate cancer-associated sequences.
Tumor cells exhibit a good conelation between malignancy and invasiveness of cells into Matrigel or some other exfracellular matrix constituent. In this assay, tumorigenic cells are typically used as host cells. Expression of a tumor suppressor gene in these host cells would decrease invasiveness of the host cells.
Techniques described in Freshney (1994), supra, can be used. Briefly, the level of invasion of host cells can be measured by using filters coated with Matrigel or some other exfracellular matrix constituent. Penefration into the gel, or through to the distal side of the filter, is rated as invasiveness, and rated histologically by number of cells and distance moved, or by prelabeling the cells with 125j and counting the radioactivity on the distal side of the filter or bottom of the dish. See, e.g., Freshney (1984), supra. Tumor growth in vivo
Effects of cancer-associated sequences on cell growth can be tested in transgenic or immune-suppressed mice. Knock-out transgenic mice can be made, in which the cancer gene is disrupted or in which a cancer gene is inserted. Knock-out transgenic mice can be made by insertion of a marker gene or other heterologous gene into the endogenous cancer gene site in the mouse genome via homologous recombination. Such mice can also be made by substituting the endogenous cancer gene with a mutated version of the cancer gene, or by mutating the endogenous cancer gene, e.g., by exposure to carcinogens.
A DNA construct is introduced into the nuclei of embryonic stem cells. Cells containing the newly engineered genetic lesion are injected into a host mouse embryo, which is re- implanted into a recipient female. Some of these embryos develop into chimeric mice that possess germ cells partially derived from the mutant cell line. Therefore, by breeding the chimeric mice it is possible to obtain a new line of mice containing the introduced genetic lesion (see, e.g., Capecchi, et al. (1989) Science 244:1288-1292). Chimeric targeted mice can be derived according to Hogan, et al. (1988) Manipulating the Mouse Embryo: A Laboratory Manual CSH Press; and Robertson (ed. 1987) Teratocarcinomas and Embryonic Stem Cells: A Practical Approach IRL Press, Washington, D.C. Alternatively, various immune-suppressed or immune-deficient host animals can be used. For example, genetically athymic "nude" mouse (see, e.g., Giovanella, et al. (1974) L Natl. Cancer Inst. 52:921-930), a SCTD mouse, a thymectomized mouse, or an inadiated mouse (see, e.g., Bradley, et al. (1978) Br. J. Cancer 38:263-272; Selby, et al. (1980) Br. J. Cancer
41:52-61) can be used as a host. Transplantable tumor cells (typically about 10^ cells) injected into isogenic hosts will produce invasive tumors in a high proportions of cases, while normal cells of similar origin will not. In hosts which developed invasive tumors, cells expressing a cancer-associated sequences are injected subcutaneously. After a suitable length of time, preferably about 4-8 weeks, tumor growth is measured (e.g., by volume or by its two largest dimensions) and compared to the control. Tumors that have statistically significant reduction (using, e.g., Student's T test) are said to have inhibited growth. Polynucleotide modulators of cancer Antisense and RNAi Polynucleotides
In certain embodiments, the activity of a cancer-associated protein is down-regulated, or entirely inhibited, by the use of an inhibitory or antisense polynucleotide, e.g., a nucleic acid complementary to, and which can preferably hybridize specifically to, a coding mRNA nucleic acid sequence, e.g., a cancer protein mRNA, or a subsequence thereof. Binding of the antisense polynucleotide to the mRNA reduces the translation and/or stability of the mRNA.
In the context of this invention, antisense polynucleotides can comprise naturally- occurring nucleotides, or synthetic species formed from naturally-occurring subunits or their close homologs. Antisense polynucleotides may also have altered sugar moieties or inter-sugar linkages. Exemplary among these are the phosphorothioate and other sulfur containing species. Analogs are comprehended by this invention so long as they function effectively to hybridize with the cancer protein mRNA. See, e.g., Isis Pharmaceuticals, Carlsbad, CA; Sequitor, Inc., Natick, MA. Such antisense polynucleotides can readily be synthesized using recombinant means, or can be synthesized in vitro. Equipment for such synthesis is sold by several vendors, including Applied Biosystems. The preparation of other oligonucleotides such as phosphorothioates and alkylated derivatives is also well known.
Antisense molecules as used herein include antisense or sense oligonucleotides. Sense oligonucleotides can, e.g., be employed to block transcription by binding to the anti-sense strand. The antisense and sense oligonucleotide comprise a single-stranded nucleic acid sequence (either RNA or DNA) capable of binding to target mRNA (sense) or DNA (antisense) sequences for cancer molecules. A prefened antisense molecule is for a cancer sequences in the Tables, or for a ligand or activator thereof. Antisense or sense oligonucleotides, according to the present invention, comprise a fragment generally at least about 14 nucleotides, preferably from about 14-30 nucleotides. The ability to derive an antisense or a sense oligonucleotide, based upon a cDNA sequence encoding a given protein is described in, e.g., Stein and Cohen (1988) Cancer Res. 48:2659-2668; and van der Krol, et al. (1988) BioTechniques 6:958-976. RNA interference is a mechanism to suppress gene expression in a sequence specific manner. See, e.g., Brumelkamp, et al. (2002) Sciencexpress (21March2002); Shaφ (1999) Genes Dev. 13:139-141; and Cathew (2001) Cun. Op. Cell Biol. 13:244-248. In mammalian cells, short, e.g., 21 nt, double stranded small interfering RNAs (siRNA) have been shown to be effective at inducing an RNAi response. See, e.g., Elbashir, et al. (2001) Nature 411:494-498. The mechanism may be used to downregulate expression levels of identified genes, e.g., treatment of or validation of relevance to disease. Ribozymes In addition to antisense polynucleotides, ribozymes can be used to target and inhibit transcription of cancer-associated nucleotide sequences. A ribozyme is an RNA molecule that catalytically cleaves other RNA molecules. Different kinds of ribozymes have been described, including group I ribozymes, hammerhead ribozymes, haiφin ribozymes, RNase P, and axhead ribozymes (see, e.g., Castanotto, et al. (1994) Adv. in Pharmacology 25: 289-317 for a general review of the properties of different ribozymes).
The general features of haiφin ribozymes are described, e.g., in Hampel, et al. (1990) Nucl. Acids Res. 18:299-304; European Patent Publication No. 0 360257; U.S. Patent No. 5,254,678. Methods of preparation are described in, e.g., WO 94/26877; Ojwang, et al. (1993) Proc. Natl. Acad. Sci. USA 90:6340-6344; Yamada, et al. (1994) Human Gene Therapy 1:39- 45; Leavitt, et al.(1995) Proc. Natl. Acad. Sci. USA 92:699-703; Leavitt, et al. (1994) Human Gene Therapy 5:1151-120; and Yamada, et al. (1994) Virology 205: 121-126.
Polynucleotide modulators of cancer may be introduced into a cell containing the target nucleotide sequence by formation of a conjugate with a ligand binding molecule, as described in WO 91/04753. Suitable ligand binding molecules include, but are not limited to, cell surface receptors, growth factors, other cytokines, or other ligands that bind to cell surface receptors. Preferably, conjugation of the ligand binding molecule does not substantially interfere with the ability of the ligand binding molecule to bind to its conesponding molecule or receptor, dr block entry of the sense or antisense oligonucleotide or its conjugated version into the cell. Alternatively, a polynucleotide modulator of cancer may be introduced into a cell containing the target nucleic acid sequence, e.g., by formation of an polynucleotide-lipid complex, as described in WO 90/10448. It is understood that the use of antisense molecules or knock out and knock in models may also be used in screening assays as discussed above, in addition to methods of freatment.
Thus, in one embodiment, methods of modulating cancer in cells or organisms are provided. In one embodiment, the methods comprise administering to a cell an anti-cancer antibody that reduces or eliminates the biological activity of an endogenous cancer protein. Alternatively, the methods comprise administering to a cell or organism a recombinant nucleic acid encoding a cancer protein. This may be accomplished in any number of ways. In a prefened embodiment, e.g., when the cancer sequence is down-regulated in cancer, such state may be reversed by increasing the amount of cancer gene product in the cell. This can be accomplished, e.g., by overexpressing the endogenous cancer gene or administering a gene encoding the cancer sequence, using known gene-therapy techniques. In a prefened embodiment, the gene therapy techniques include the incoφoration of the exogenous gene using enhanced homologous recombination (EHR), e.g., as described in PCT/US93/0386. Alternatively, e.g., when the cancer sequence is up-regulated in cancer, the activity of the endogenous cancer gene is decreased, e.g., by the administration of a cancer antisense or other inhibitor, e.g., RNAi.
In one embodiment, the cancer proteins of the present invention may be used to generate polyclonal and monoclonal antibodies to cancer proteins. Similarly, the cancer proteins can be coupled, using standard technology, to affinity chromatography columns. These columns may then be used to purify cancer antibodies useful for production, diagnostic, or therapeutic piuposes. In a prefened embodiment, the antibodies are generated to epitopes unique to a cancer protein; that is, the antibodies show little or no cross-reactivity to other proteins. The cancer antibodies may be coupled to standard affinity chromatography columns and used to purify cancer proteins. The antibodies may also be used as blocking polypeptides, as outlined above, since they will specifically bind to the cancer protein. Methods of identifying variant cancer-associated sequences
Without being bound by theory, expression of various cancer sequences is conelated with cancer. Accordingly, disorders based on mutant or variant cancer genes may be determined. In one embodiment, the invention provides methods for identifying cells containing variant cancer genes, e.g., determining all or part of the sequence of at least one endogenous cancer gene in a cell. In a prefened embodiment, the invention provides methods of identifying the cancer genotype of an individual, e.g., determining all or part of the sequence of at least one cancer gene of the individual. This is generally done in at least one tissue of the individual, and may include the evaluation of a number of tissues or different samples of the same tissue. The method may include comparing the sequence of the sequenced cancer gene to a known cancer gene, e.g., a wild-type gene.
The sequence of all or part of the cancer gene can then be compared to the sequence of a known cancer gene to determine if any differences exist. This can be done using known homology programs, such as Bestfit, etc. In a prefened embodiment, the presence of a difference in the sequence between the cancer gene of the patient and the known cancer gene conelates with a disease state or a propensity for a disease state, as outlined herein.
In a prefened embodiment, the cancer genes are used as probes to determine the number of copies of the cancer gene in the genome.
In another prefened embodiment, the cancer genes are used as probes to determine the chromosomal localization of the cancer genes. Information such as chromosomal localization finds use in providing a diagnosis or prognosis in particular when chromosomal abnormalities such as translocations, and the like are identified in the cancer gene locus. Adminisfration of pharmaceutical and vaccine compositions
In one embodiment, a therapeutically effective dose of a cancer protein or modulator thereof, is administered to a patient. By "therapeutically effective dose" herein is meant a dose that produces effects for which it is administered. The exact dose will depend on the puφose of the freatment, and will be ascertainable using known techniques. See, e.g., Ansel, et al. (1999) Pharmaceutical Dosage Forms and Drug Delivery Lippincott; Lieberman (1992) Pharmaceutical Dosage Forms (vols. 1-3) Dekker, ISBN 0824770846, 082476918X, 0824712692, 0824716981; Lloyd (1999) The Art, Science and Technology of Pharmaceutical Compounding Amer. Pharmaceut. Assn.; and Pickar (1998) Dosage Calculations Thomson. Adjustments for cancer degradation, systemic versus localized delivery, and rate of new protease synthesis, as well as the age, body weight, general health, sex, diet, time of administration, drug interaction, and the severity of the condition may be necessary. U.S. Patent Application No. 09/687,576, further discloses the use of compositions and methods of diagnosis and treatment in cancer.
A "patient" for the puφoses of the present invention includes both humans and other animals, particularly mammals. Thus the methods are applicable to both human therapy and veterinary applications. In the prefened embodiment the patient is a mammal, preferably a primate, and in the most prefened embodiment the patient is human.
The administration of the cancer proteins and modulators thereof of the present invention can be done in a variety of ways, including, but not limited to, orally, subcutaneously, intravenously, intranasally, transdermally, intraperitoneally, intramuscularly, intrapulmonary, vaginally, rectally, or infraocularly. In some instances, e.g., in the treatment of wounds and inflammation, the cancer proteins and modulators may be directly applied as a solution or spray. The pharmaceutical compositions of the present invention comprise a cancer protein in a form suitable for administration to a patient. In the prefened embodiment, the pharmaceutical compositions are in a water soluble form, such as being present as pharmaceutically acceptable salts, which is meant to include both acid and base addition salts. "Pharmaceutically acceptable acid addition salt" refers to those salts that retain the biological effectiveness of the free bases and that are not biologically or otherwise undesirable, formed with inorganic acids such as hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, and the like, and organic acids such as acetic acid, propionic acid, glycolic acid, pyruvic acid, oxalic acid, maleic acid, malonic acid, succinic acid, fumaric acid, tartaric acid, citric acid, benzoic acid, cinnamic acid, mandelic acid, methanesulfonic acid, ethanesulfonic acid, p-toluenesulfonic acid, salicylic acid, and the like. "Pharmaceutically acceptable base addition salts" include those derived from inorganic bases such as sodium, potassium, lithium, ammonium, calcium, magnesium, iron, zinc, copper, manganese, aluminum salts, and the like. Particularly prefened are the ammonium, potassium, sodium, calcium, and magnesium salts. Salts derived from pharmaceutically acceptable organic non-toxic bases include salts of primary, secondary, and tertiary amines, substituted amines including naturally occurring substituted amines, cyclic amines and basic ion exchange resins, such as isopropylamine, trimethylamine, diethylamine, triethylamine, tripropylamine, and ethanolamine.
The pharmaceutical compositions may also include one or more of the following: carrier proteins such as serum albumin; buffers; fillers such as microcrystalline cellulose, lactose, corn and other starches; binding agents; sweeteners and other flavoring agents; coloring agents; and polyethylene glycol.
The pharmaceutical compositions can be administered in a variety of unit dosage forms depending upon the method of administration. For example, unit dosage forms suitable for oral adminisfration include, but are not limited to, powder, tablets, pills, capsules and lozenges. It is recognized that cancer protein modulators (e.g., antibodies, antisense constructs, ribozymes, small organic molecules, etc.) when administered orally, should be protected from digestion. This is typically accomplished either by complexing the molecule(s) with a composition to render it resistant to acidic and enzymatic hydrolysis, or by packaging the molecule(s) in an appropriately resistant carrier, such as a liposome or a protection barrier. Means of protecting agents from digestion are available. The compositions for administration will commonly comprise a cancer protein modulator dissolved in a pharmaceutically acceptable carrier, preferably an aqueous carrier. A variety of aqueous carriers can be used, e.g., buffered saline and the like. These solutions are sterile and generally free of undesirable matter. These compositions may be sterilized by conventional, well known sterilization techniques. The compositions may contain pharmaceutically acceptable auxiliary substances as required to approximate physiological conditions such as pH adjusting and buffering agents, toxicity adjusting agents, and the like, e.g., sodium acetate, sodium chloride, potassium chloride, calcium chloride, sodium lactate, and the like. The concentration of active agent in these formulations can vary widely, and will be selected primarily based on fluid volumes, viscosities, body weight, and the like in accordance with the particular mode of administration selected and the patient's needs (e.g., (1980) Remington's Pharmaceutical Science (18th ed.) Mack, and Hardman and Limbird (eds. 2001) Goodman and Gilman: The Pharmacological Basis of Therapeutics (10th ed.) McGraw-Hill. Thus, a typical pharmaceutical composition for intravenous administration would be about 0.1 to 10 mg per patient per day. Dosages from 0.1 up to about 100 mg per patient per day may be used, particularly when the drug is administered to a secluded site and not into the blood stream, such as into a body cavity or into a lumen of an organ. Substantially higher dosages are possible in topical administration. Actual methods for preparing parenterally administrable compositions will be known or apparent. The compositions containing modulators of cancer proteins can be administered for therapeutic or prophylactic treatments. In therapeutic applications, compositions are administered to a patient suffering from a disease (e.g., a cancer) in an amount sufficient'to cure or at least partially anest the disease and its complications. An amount adequate to accomplish this is defined as a "therapeutically effective dose." Amounts effective for this use will depend upon the severity of the disease and the general state of the patient's health. Single or multiple administrations of the compositions may be administered depending on the dosage and frequency as required and tolerated by the patient. In any event, the composition should provide a sufficient quantity of the agents of this invention to effectively treat the patient. An amount of modulator that is capable of preventing or slowing the development of cancer in a mammal is refened to as a "prophylactically effective dose." The particular dose required for a prophylactic treatment will depend upon the medical condition and history of the mammal, the particular cancer being prevented, as well as other factors such as age, weight, gender, administration route, efficiency, etc. Such prophylactic treatments may be used, e.g., in a mammal who has previously had cancer to prevent a recunence of the cancer, or in a mammal who is suspected of having a significant likelihood of developing cancer based, at least in part, upon gene expression profiles. Vaccine strategies may be used, in either a DNA vaccine form, or protein vaccine.
It will be appreciated that the present cancer protein-modulating compounds can be administered alone or in combination with additional cancer modulating compounds or with other therapeutic agent, e.g., other anti-cancer agents or treatments.
In numerous embodiments, one or more nucleic acids, e.g., polynucleotides comprising nucleic acid sequences set forth in the Tables, such as RNAi, antisense polynucleotides or ribozymes, will be introduced into cells, in vitro or in vivo. The present invention provides methods, reagents, vectors, and cells useful for expression of cancer-associated polypeptides and nucleic acids using in vitro (cell-free), ex vivo or in vivo (cell or organism-based) recombinant expression systems. The particular procedure used to introduce the nucleic acids into a host cell for expression of a protein or nucleic acid is application specific. Many procedures for introducing foreign nucleotide sequences into host cells may be used. These include the use of calcium phosphate transfection, spheroplasts, electroporation, liposomes, microinjection, plasma vectors, viral vectors, and other well known methods for introducing cloned genomic DNA, cDNA, synthetic DNA, or other foreign genetic material into a host cell (see, e.g., Berger and Kimmel (1987) Guide to Molecular Cloning Techniques from Methods in Enzymology (vol. 152) Academic Press; Ausubel, et al. (eds. 1999 and supplements) Cuπent Protocols Lippincott; and Sambrook, et al. (2001) Molecular Cloning: A Laboratory Manual (3d ed., Vol. 1-3) CSH Press. In a prefened embodiment, cancer proteins and modulators are administered as therapeutic agents, and can be formulated as outlined above. Similarly, cancer genes (including both the full-length sequence, partial sequences, or regulatory sequences of the cancer coding regions) can be administered in a gene therapy application. These cancer genes can include inhibitory applications, e.g., as inhibitory RNA, gene therapy (e.g., for incoφoration into the genome), or antisense compositions.
Cancer polypeptides and polynucleotides can also be administered as Vaccine compositions to stimulate HTL, CTL, and antibody responses. Such vaccine compositions can include, e.g., lipidated peptides (see, e.g.Nitiello, et al. (1995) J. Clin. Invest. 95:341-349), peptide compositions encapsulated in poly(DL-lactide-co-glycolide) ("PLG") microspheres (see, e.g., Eldridge, et al. (1991) Molec. hnmunol. 28:287-294,; Alonso, et al. (1994) Vaccine 12:299-306; Jones, et al. (1995) Vaccine 13:675-681), peptide compositions contained in immune stimulating complexes (ISCOMS) (see, e.g., Takahashi, et al. (1990) Nature 344:873- 875; Hu, et al. (1998) Clin Exp Immunol. 113:235-243), multiple antigen peptide systems (MAPs) (see, e.g., Tarn (1988) Proc. Natl. Acad. Sci. USA 85:5409-5413; Tarn (1996) Immunol. Methods 196:17-32), peptides formulated as multivalent peptides; peptides for use in ballistic delivery systems, typically crystallized peptides, viral delivery vectors (Perkus, et al., p. 379, in Kaufitnann (ed. 1996) Concepts in Vaccine Development de Gruyter; Chakrabarti, et al. (1986) Nature 320:535-537; Hu, et al. (1986) Nature 320:537-540; Kieny, et al. (1986) Bio/Technology 4:790-795: Top, et al. (1971) J. Infect. Pis. 124:148-154; Chanda, et al. (1990) Virology 175:535-547), particles of viral or synthetic origin (see, e.g., Kofler, et al. (1996) Immunol. Methods 192:25-35; Eldridge, et al. (1993) Sem. Hematol. 30:16-24; Falo, et al. (1995) Nature Med. 1:649-653), adjuvants (Wanen, et al. (1986) Annu. Rev. Immunol. 4:369- 388; Gupta, et al. (1993) Vaccine 11:293-306), liposomes (Reddy, et al. (1992) J. Immunol. 148:1585-1589; Rock (1996) Immunol. Today 17:131-137), or, naked or particle absorbed cDNA (Ulmer, et al. (1993) Science 259:1745-1749; Robinson, et al. (1993) Vaccine 11:957- 960; Shiver, et al., p 423, in Kaufrnann (ed. 1996) Concepts in Vaccine Development de Gruyter; Cease and Berzofsky (1994) Annu. Rev. Immunol. 12:923-989; and Eldridge, et al.
(1993) Sem. Hematol. 30:16-24). Toxin-targeted delivery technologies, also known as receptor mediated targeting, such as those of Avant hnmunotherapeutics, Inc. (Needham, Massachusetts) may also be used.
Vaccine compositions often include adjuvants. Many adjuvants contain a substance designed to protect the antigen from rapid catabolism, such as aluminum hydroxide or mineral oil, and a stimulator of immune responses, such as lipid A, Bortadella pertussis, or . Mycobacterium tuberculosis derived proteins. Certain adjuvants are commercially available as, e.g., Freund's Incomplete Adjuvant and Complete Adjuvant (Difco Laboratories, Detroit, MI); Merck Adjuvant 65 (Merck and Company, Inc., Rahway, NJ); AS-2 (SmithKline Beecham, Philadelphia, PA); aluminum salts such as aluminum hydroxide gel (alum) or aluminum phosphate; salts of calcium, iron, or zinc; an insoluble suspension of acylated tyrosine; acylated sugars; cationically or anionically derivatized polysaccharides; polyphosphazenes; biodegradable microspheres; monophosphoryl lipid A and quil A. Cytokines, such as GM-CSF, interleukin-2, -7, -12, and other like growth factors, may also be used as adjuvants.
Vaccines can be administered as nucleic acid compositions wherein DNA or RNA encoding one or more of the polypeptides, or a fragment thereof, is administered to a patient. This approach is described, for instance, in Wolff et. al. (1990) Science 247:1465-1468, as well as U.S. Patent Nos. 5,580,859; 5,589,466; 5,804,566; 5,739,118; 5,736,524; 5,679,647; WO 98/04720; and in more detail below. Examples of DNA-based delivery technologies include "naked DNA", facilitated (bupivicaine, polymers, peptide-mediated) delivery, cationic lipid complexes, and particle-mediated ("gene gun") or pressure-mediated delivery (see, e.g., U.S. Patent No. 5,922,687).
For therapeutic or prophylactic immunization puφoses, the peptides of the invention can be expressed by viral or bacterial vectors. Examples of expression vectors include attenuated viral hosts, such as vaccinia or fowlpox. This approach involves the use of vaccinia virus, e.g., as a vector to express nucleotide sequences that encode cancer polypeptides or polypeptide fragments. Upon introduction into a host, the recombinant vaccinia virus expresses the immunogenic peptide, and thereby elicits an immune response. Vaccinia vectors and methods useful in immunization protocols are described in, e.g., U.S. Patent No. 4,722,848. Another vector is BCG (Bacille Calmette Guerin). BCG vectors are described in Stover, et al. (1991) Nature 351 :456-460. A wide variety of other vectors are availablel for therapeutic administration or immunization, e.g., adeno and adeno-associated virus vectors, retroviral vectors, Salmonella typhi vectors, detoxified anthrax toxin vectors, and the like. See, e.g., Shata, et al. (2000) Mol Med Today 6:66-71; Shedlock, et al. (2000) J. Leukoc. Biol. 68:793- 806; Hipp, et al. (2000) In Vivo 14:571-85.
Methods for the use of genes as DNA vaccines are well known, and include placing a cancer gene or portion of a cancer gene under the control of a regulatable promoter or a tissue- specific promoter for expression in a cancer patient. The cancer gene used for DNA vaccines can encode full-length cancer proteins, but more preferably encodes portions of the cancer proteins including peptides derived from the cancer protein. In one embodiment, a patient is immunized with a DNA vaccine comprising a plurality of nucleotide sequences derived from a cancer gene. For example, cancer-associated genes or sequence encoding subfragments of a cancer protein are introduced into expression vectors and tested for their immunogenicity in the context of Class I MHC and an ability to generate cytotoxic T cell responses. This procedure provides for production of cytotoxic T cell responses against cells which present antigen, including intracellular epitopes.
In a prefened embodiment, DNA vaccines include a gene encoding an adjuvant molecule with the DNA vaccine. Such adjuvant molecules include cytokines that increase the immunogenic response to the cancer polypeptide encoded by the DNA vaccine. Additional or alternative adjuvants are available.
In another prefened embodiment, cancer genes find use in generating animal models of cancer. When the cancer gene identified is repressed or diminished in cancer tissue, gene therapy technology, e.g., wherein inhibitory or antisense RNA directed to the cancer gene will also diminish or repress expression of the gene. Animal models of cancer find use in screening for modulators of a cancer-associated sequence or modulators of cancer. Similarly, transgenic animal technology, including gene knockout technology, e.g., as a result of homologous recombination with an appropriate gene targeting vector, will result in the absence or increased expression of the cancer protein. When desired, tissue-specific expression or knockout of the cancer protein may be necessary.
It is also possible that the cancer protein is overexpressed in cancer. As such, transgenic animals can be generated that overexpress the cancer protein. Depending on the desired expression level, promoters of various strengths can be employed to express the fransgene. Also, the number of copies of the integrated fransgene can be determined and compared for a determination of the expression level of the transgene. Animals generated by such methods will find use as animal models of cancer and are additionally useful in screening for modulators to treat cancer. Kits for Use in Diagnostic and/or Prognostic Applications
For use in diagnostic, research, and therapeutic applications suggested above, kits are also provided by the invention. In diagnostic and research applications, such kits may include at' least one of the following: assay reagents, buffers, cancer-specific nucleic acids or antibodies, hybridization probes and/or primers, antisense polynucleotides, ribozymes, dominant negative cancer polypeptides or polynucleotides, small molecule inhibitors of cancer-associated sequences etc. A therapeutic product may include sterile saline or another pharmaceutically acceptable emulsion and suspension base.
In addition, the kits may include instructional materials containing instructions (e.g., protocols) for the practice of the methods of this invention. While the instructional materials typically comprise written or printed materials, they are not limited to such. A medium capable of storing such instructions and communicating them to an end user is contemplated by this invention. Such media include, but are not limited to, electronic storage media (e.g., magnetic discs, tapes, cartridges, chips), optical media (e.g., CD ROM), and the like. Such media may include addresses to internet sites that provide such instructional materials.
The present invention also provides for kits for screening for modulators of cancer- associated sequences. Such kits can be prepared from readily available materials and reagents. For example, such kits can comprise one or more of the following materials: a cancer-associated polypeptide or polynucleotide, reaction tubes, and instructions for testing cancer-associated activity. Optionally, the kit contains biologically active cancer protein. A wide variety of kits and components can be prepared according to the present invention, depending upon the intended user of the kit and the particular needs of the user. Diagnosis would typically involve evaluation of a plurality of genes or products. The genes will typically be selected based on conelations with important parameters in disease which may be identified in historical or outcome data.
EXAMPLES Example 1 : Gene Chip Analysis
Molecular profiles of various normal and cancerous tissues were determined and analyzed using gene chips. RNA was isolated and gene chip analysis was performed as described (Glynne, et al. (2000) Nature 403:672-676; Zhao, et al. (2000) Genes Dev. 14:981- 993).
Table 1 lists medical conditions, abnormalities, or organs affected by disease, referred to in Tables 2A and 3A for which markers have been identified, and other related medical conditions (including vaπous stages and/or metastases) in which those markers will also be useful, e g , in therapeutic, diagnostic, prognostic, subsetting, vaccine, and other uses blood vessels/angiogenesis hemangiomas, lymphangiomas, aπgiosarcoma, lymphangiosarcoma, Kaposi's sarcoma, wound healing, tissue remodeling, psoπasis, ischemic, heart disease, inflammatory diseases (e g , arthntis asthma, chronic bronchitis), atherosclerosis, endomelπosis, presumed ocular histoplasmosis syndrome, hypoxia solid tumors lymphomas, lymphadenitis, lymphangitis, autoimmune diseases (e g , RA, SLE, juvenile chronic arthntis, pigmented villoπodular synovitis, etc ), retinal neovasculaπzatioπ syndromes (e g , diabetic retmopathy, macular degeneration, presumed ocular histoplasmosis syndrome, etc ), scleπtis/conjunctivitis, hypertrophic scars (keloid), birth control, uteπne fibroids bladder carcinoma in situ, papillary carcinomas, transitional cell carcinoma, squamous cell carcinoma bone Ewing sarcoma, sarcomas ansing from skeletal and extraskeletal connective tissues, including the peripheral nervous system (e g chondrosarcoma osteosarcoma) brain glioblastoma, oligodendroglioma anablastic astrocytoma, meπ gioma medulablastoma, neuroblastoma ependymoma, schwannoma, craniopharyngioma pmeoblastoma, pmeocytoma, neurofibroma neurofibrosarcoma malignant peπpheral nerve sheath tumors, granular cell tumors, plexosarcoma, ganglioπeuroblastoma neuroepithelioma, neuroma, ganglioneuroma breast ductal carcinoma in situ, tabular carcinoma in situ cervix cancer of the cervix vagina, or vulva colon/rectum precancerous colorectal disease (e g , neoplastic polyps (adenomas), familial adenomatous polyposis, ulcerative colitis), colon cancer, e g , epithelial tumor (e g , adenocarcinoma, mucinous adenocarcinoma, signet nng cell adenocarcinoma squamous cell carcinoma, adeπosquamous carcinoma undiffereπtiated carcinoma, unclassified carcinoma), cannoid tumor (e g , argentaffin, πonargentaffin, composite), non-epithelial tumor (e g , leimyo sarcoma, others), inflammatory bowel disease (e g , ulcerative colitis, Crohn's disease (granulomatous colitis), dysplasia), rectal cancer, cancer of the anal region (e g , squamous cell carcinoma, transitional carcinoma, adenocarcinoma, carcinoma papillary villous carcinoma, mucinous adenocarcinoma, melanoma) esophagus premaligπant or predisposing conditions (e g , esophagitis) squamous cell cancers (e g , cancers of the head and neck, lung, or cervix), gastrodigestive carcinomas
(e g , cancers of the stomach colon, or rectum) fibrosis lung fibrosis (idiopathic pulmonary fibrosis, hypersensitivity pneumonitis.interstitial pneumonitis, nonspecific idiopathic pneumonitis), chronic obstructive pulmonary disease (e g , emphysema, chronic bronchitis), asthma, bronchiectasis, cirrhosis (liver fibrosis), renal fibrosis, scleroderma, wound healing , head and neck tumors of the nasal cavity, paranasal sinuses, nasopharynx, oral cavity, oral pharynx, lip, larynx, hypopharynx, salivary glands, paragangliomas, esophagus kidney clear cell (nonpapillary) carcinoma papillary carcinoma, chromophobe renal carcinoma, hypernephroma adenocarcinoma, sporadic renal carcinomas, hereditary renal carcinomas (von Hippel ϋndau disease), carcinoma of the renal pelvis, ureteral carcinoma, fibroma, papillary adenoma, angiomyolipoma, oncocytoma leukocytes acute ly phoblastic leukemia/lymphoma, chronic lymphocytic leukemia, follicular lymphoma, large B-cell lymphoma Burkitt lymphoma, plasma cell neoplasms, mantle cell lymphoma lymphoplasmacytic lymphoma, peπpheral T-cell lymphoma, adult T-cell leukemia lymphoma, Hodgkin disease, acute myelogenous leukemia, chronic myelogenous leukemia, thymic hyperplasia, hairy cell leukemia, malignant transformation, mappropπate activation or abnormalities of leukocytes (e g , immature, precursor B (pre-B) or precursor T (pre T) lymphocytes, monocytes, neutrophils eosmophils, basophils, dendπtic cells, lymphoblasts), arthntis, inflammation, leukocytosis, lymphadenitis, lymphangitis, bacteremia, chronic nonspecific lymphadenitis, psonasis, wound healing liver hepatitis (e g , types A, B, C) benign epithelial tumors and tumor bile conditions, pπmary malignant epithelial tumors, pn ary malignant meseπchymal tumors, tumors of the gallbladder or bile duct lung lung cancer, small cell lung carcinoma (oat cell carcinoma), non small cell carcinomas (e g , squamous cell carcinoma, adenocarcinoma large cell lung carcinoma, carcmoid, granulomatous), fibrasis (idiopathic pulmonary fibrosis, hypersensitivity pneumonitis.interstitial pneumonitis, nonspecific idiopathic pneumonitis), chronic obstructive pulmonary disease (e g , emphysema, chronic bronchitis), asthma, bronchiectasis, esophageal cancer ovary ovaπan carcinoma (e g , epithelial (serous tumors, mucinous tumors, endometnoid tumors), germ cell (e g , teratomas, chonocarcinomas, polyembryomas, embryomal carcinoma, endodermal sinus tumor, dysgermmoma, gonadoblastoma), stromal carcinomas (e g , granulosal stromal cell tumors)), fallopian tube carcinoma peπtoπeal carcinoma, leiomyoma pancreas adenocarcinoma, ductal adenocarcinoma, mucinous cyst adenocarcinoma, acmar cell carcinoma, unclassified large cell carcinoma, small cell carcinoma paπcreatoblastoma, duct-ectatio mucin-hypersecreting tumor, mucinous cyst adenoma papillary cystic neoplasm, serous cyst adenoma, diabetes melitis, chronic pancreatitis prostate epithelial neoplasms (e g adenocarcinoma, small cell tumors, transitional cell carcinoma, carcinoma in situ, and basal cell carcinoma), carcinosarcoma, non-epithelial neoplasms (e g , mesenchymal and lymphoma), germ cell tumors, prostate intraepithelial neoplasia (PIN), hormone independent prostate cancer, benign prostate hyperplasia, prostatitis skin/melanoma melanoma, lentigo (common benign localized hyperplasia of melanocytes), nevocellular nevi (congenital or acquired neoplasm of melanocytes), actinic keratosis (overgrowth of outer layers of skin), basal cell carcinoma, Merkel cell carcinoma, benign fibrous histiocytoma (dermal neoplasms of fibroblasts and histiocytes), dermatofibrosarcoma pratuberans (well differentiated fibrosarcoma of the skin), xanthomas (tumor-like collections of foamy histiocytes within the dermis), dermal vascular tumors, seborrheic keratoses (benign tumor), acanthosis nigπcans (benign or malignant hyperplasia and hyperpigmentation of skin), and squamous cell carcinomas of the skin, lung, cervix, esophagus, uterus, head, neck, or bladder soft tissue soft tissue tumors (e g , fibrosarcoma, liposarcoma, leiomyosarcoma, histiocytoma, fibrohistiocytic sarcoma) smooth muscle tumors (e g , rhabdomyoma, rhabdomyosarcoma) tumors of the blood and lymph vessels (e g , aπgiosarcoma, lymphangiosarcoma, Kaposi's sarcoma), peπvascular tumors (e g , glomus tumors, hemangiopencytoma), synovial tumors (e g , mesothelioma), neural tumors (e g , neurofibroma, neurofibrosarcoma, malignant peπpheral nerve sheath tumors, granular cell tumors, plexosarcoma, ganglioneuroblastoma, neuroepithelioma, extraskeletal Ewing's sarcoma, schwannoma, neuroma, ganglioneuroma), paraganglioma, extraskeletal cartilaginous and osseous tumors (e g , chondrosarcoma, osteosarcoma), plunpotential mesenchymal tumors, epitheliod sarcomas, rhabdoid tumors, desmoplastic small cell tumors, alveolar sarcoma stomach adenocarcinoma, squamous cell carcinoma, adenoacanthoma, carcmoid, leiomyosarcoma, gastritis (chronic atrophic, H pylon associated), hyperplastic polyps, lipoma, leiomyoma, esophageal adenocarcmomas testicles germ cell tumors (including semmomas, embryonal carcinomas, teratomas, chonocarcinomas, yolk sac tumors), sex chord stromal tumors (including Leydig cell tumors, Sertoli cell tumors, and Granulosa cell tumors), germ cell and gonadal stromal elements (e g , goπadoblastomas), adnexal and paratesticular tumors (e g , mesotheliomas, soft tissue sarcomas, and adnexal of the rete testes), miscellaneous neoplasms (including carcmoid, lymphoma, and cysts) uterus epithelial tumors (e g , endometnoid, papillary endometnoid, papillary serous, clear cell, mucinous), mesenchymal tumors (e g , endometnal stromal sarcoma leiomyosarcoma, nonspecific sarcomas), mixed tumors (e g , malignant mixed mulleπan tumors, adeπosarcoma) 5
- Tables 2B-72B, 76B, and 79B list accession numbers for Pkeys lacking UmgenelD's for Tables 2A-72A, 76A, and 79A, respectively For each probeset is listed gene cluster number 0 from which oligonucleotides were designed Gene clusters were compiled using sequences denved from Genbank ESTs and mRNAs These sequences were clustered based on sequence similaπty using Clusteππg and Alignment Tools (DoubleTwist, Oakland California) Genbank accession numbers for sequences compπsing each cluster are listed in the "Accession" column
Tables 2C-72C, 76C, and 79C list genomic positioning for Pkeys lacking Unigene ID's and accession numbers in Tables 2A-72A, 76A, and 79A, respectively For each predicted J exon is listed genomic sequence source used for prediction Nucleotide locations of each predicted exon are also listed
Table 2A, Disease Indications and Preferred Utilities for Selected Genes
Table 2A provides preferred disease indications and preferred utilities for about 413 selected genes These genes were identified using Eos/Affymetπx Genechip arrays 0
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number
UnigenelD Unigene ID number Unigene Title Unigene gene title
Disease preferred diseases indicated for selected gene as descπbed in table 1 and abbreviated as follows blad (bladder diseases), angio (blood vessel diseases), EWS
(bone diseases), glio (brain diseases), breast (breast diseases), cerv (cervical diseases), colon (colorectal diseases), esoph (esophageal diseases), fibro (fibrosis diseases), headnk (head & neck diseases), leio (leiomyoma diseases), leuk (leukocyte diseases), hepC (liver diseases), lung (lung diseases) ovar (ovanan 5 diseases) endo (ovanan endometnoid diseases), omuo (ovanan mucinous diseases), pane (pancreatic diseases), pros (prostate diseases), renal (renal diseases), sarc (soft tissue and bone diseases) mela (skin diseases), stom (stomach diseases), test (testicular diseases), uter (utenne diseases) Utility preferred utilities for selected gene as descnbed in the text and abbreviated as follows CTL (DNA vaccine target), drag (diagnostic or prognostic target), mAb
(monoclonal antibody target), s m (small molecule target) 0 Pkey, ExAccn, UmgenelD, Unigene Title Disease, Utility
102892, BE440042, Hs 83326, matnx metalloprotemase 3 (st, headnk, mAb+diag+s m 104865, T79340, Hs 22575, B-cell CLL/lymphoma 6, member , angio, CTL 104978, AI199268, Hs 19322, Homo sapiens, Similar to RIKEN, colon, lung, pros, blad, stom, CTL 5 109424, NM_005329, Hs 85962, hyaluronan synthase 3, blad, lung, mAb+s m
110765 AK000322, Hs 18457, hypothetical protein FU20315, colon, pros, stom, uter; mAb+diag 110906, AA035211, Hs 17404, SOX7 SRY (sex determining regi, angio, blad, CTL 115522, BE614387, Hs 333893, c Myc target JP01, colon, lung, blad, pane, CTL 116176, AA311152, Hs 288708, hypothetical protein FLJ21562, colon, CTL 0 118695, AK000465, Hs 50081, KIAA1199 protein, colon, lung, diag
123049, BE047680, Hs 211869, dickkopf (Xenopus laevis) homo, EWS, mAb+diag 131486, F06972, Hs 27372 endothelial tyrosine kinase (E, angio CTL+s m 133370, AF245505 Hs 72157, Adlican, breast, lung, pane, diag 310016, AW449612, Hs 152475, ESTs, colon, GTL 5 322303, AI357412, Hs 157601, ESTs, colon, pros, fibro, breast, CTL+diag
400289, X07820, Hs 2258, matnx metalloprotemase 10 (s, angio, blad, lung, cerv, ovar, headnk, esoph, mAb+diag+s m 400297, AI127076, Hs 288381, hypothetical protein DKFZp5640, breast, blad, colon, pros, mAb 400303, AA242758, Hs 79136, UV-1 protein, estrogen regula, breast, ovar, pros, stom, uter, blad, lung, neadπk, mAb 400843, , , N _003105* Homo sapiens sortil, blad, s m 0 402075, , , ENSPOO000251O56* Plasma membra, blad, lung, headnk, cerv, mela, esoph, mAb+diag 402901, , , NM_025206* Homo sapiens hypoth, blad , CTL 404287, , , FGENESH predicted novel CUB-do, pane, lung, colon, uter, esoph, mAb+s m 404682, , , ortholog of mouse polydomain p, pane, diag 404875, , , NM_022819* Homo sapiens phosph, blad, CTL+s m 5 404977, , , Insulin like growth factor 2 (, blad, ovar, sarc, mAb+diag
405033, , , C1002652* gι|544327|sp|Q04799|, blad, s 406400, , , kallikrein 8 (neuropsin/ovasin, ovar, uter; diag 406964, M21305, , FGENES predicted novel secrete, angio, blad, fibro, sarc, diag 407603, AW955705, Hs 62604, Homo sapiens, clone IMAGE 4299, glio, blad, CTL 0 407792, AI077715, Hs 39384, putative secreted ligand homol, ovar, uter, cerv, pane, mAb+diag
407811, AW190902, Hs 40098, cysteine knot superfamily 1, B, blad, pane, stom, uter, lung esoph, diag 407836, T79340, Hs 22575, B-cell CLL/lymphoma 6, member , angio, CTL 407975, X89426, Hs 41716, endothelial cell specific mole, angio, renal, diag 408243, Y00787, Hs 624, interleukin 8, blad, stom, headnk, cerv, lung, angio, esoph, pane, diag 5 408367, AK001178, Hs 4442 , Homo sapiens orphan neurotrans, mela, mAb+s m
408369, R38438, Hs 118747, SLC15A2 Solute earner family , pros, lung, fibro, uter, glio, cerv, ovar; mAb 408380, AF123050, Hs 44532, diubiquitiπ, lung, blad, headnk, pane, stom, fibro, esoph, mela, CTL
408482, NM_000676, Hs 45743, adeπosine A2b receptor, lung, esoph, headnk, colon, mAb+s m
408562, AI436323, Hs 31141 , roundabout (axon guidance rece, uter, fibro, sarc, mAb+s m O 408790, AW580227, Hs 47860, neurotrophic tyrosine kinase, , lung, mAb+s m
408908, BE296227, Hs 250822, seπne/threomne kinase 15, blad, lung, headnk, sto .colon, s m
409041, AB033025, Hs 50081, Hypothetical protein, XP_05186, uter, ovar, lung, colon, stom, headnk, breast, pane, CTL+diag
409079, W87707, Hs 82065, interleukin 6 signal transduce, breast, pros, mAb+s
409103, AF251237, Hs 112208, XAGE-1 protein, lung, CTL 5 409178, BE393948, Hs 50915, kallikrein 5, ovar, breast, mela, diag
409220, BE243323, Hs 51233, tumor necrosis factor receptor; angio, renal, colon, stom, mAb+s m.
409420, Z15008, Hs 54451, laminin, gamma 2 (nicein (100k, lung, headnk, pane, stom, cerv, esoph, blad, diag
409632, W74001, Hs 55279, seπne (or cysteine) proteinas, lung, blad, headnk, diag
409663, AI743750, Hs 98306, KIAA1862 protein, renal, CTL 0 409757, NM_001898, Hs 123114, cystatin SN, pane, stom, lung, blad, diag
409889, AW630041, Hs 56937, suppression of tumoπgenicity , colon, ovar, pros, mAb+s m
409893, AW247090, Hs 57101, minichromosome maintenance def; lung, cerv, blad, test, esoph, CTL+s m
409956, AW103364, Hs 727, inhibin, beta A (activin A, ac, breast, pane, ovar, colon, headnk, lung, blad, esoph, diag
410001, AB041036, Hs 57771, kallikrein 11, ovar, pros, uter, cerv, lung , diag 5 410055, AJ250839, Hs 58241, gene for senne/threonine prot, renal, s m
410153, BE311926, Hs 15830, hypothetical protein FU12691, renal.blad, CTL
410274, AA381807, Hs 336402, hypoxia-mducible protein 2, lung, renal, CTL
410309, BE043077, Hs 278153, alpha-2,8-sιalyltransferase II, pane, s m
410407, X66839, Hs 63287, carbonic anhydrase IX, renal, lung, colon, stom, ovar, uter, blad, sarc, mAb+s m 0 410418, D31382, Hs 63325, transmembrane protease, senne, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m
411274, NM_002776, Hs 69423, kallikrein 10, colon, ovar, uter, cerv, headk, pane, diag
411411, AA345241, Hs 55950, ESTs, Weakly similar to K1AA13, renal, mAb+s m
411773, NM_006799, Hs 72026, protease, seπne, 21 (testisin, ovar, diag
411975, AI916058, Hs 144583, 3'UTR of dead πnger (Drosoph, test, colon, CTL 75 412078, X69699, Hs 73149, paired box gene 8, ovaπ CTL
412140, AA219691, Hs 73625, RAB6 interxting, kinesin-like, lung, blad, headnk, breast ovar, pane, angio, test, mela, s m
412314, AA825247, Hs 356084, G protein-coupled receptor 27 , ovar, uter, test, mAb+s m
412609, Z48804, Hs 74124, ocular albinism 1 (Nettleship-, mela, s m
412628, AI972402, Hs 306051, hypothetical protein MGC2648, pros, diag O O 412709, AL022327, Hs 74518, KIAA0027 protein, glio, sarc, mAb+s m
412719, AW016610, Hs 816, ESTs, lung, headnk, blad, glio, cerv, sarc, s
412959, D87458, Hs 75090, KIAA0282 protein, glio CTL+s m
413048, M93221, Hs 75182, mannose receptor, C type 1 , fibro, pane, mAb 413063, AL035737, Hs 75184, chitinase 3-lιke 1 (cartilage , glio, ovar, blad, lung , diag
413278, BE563085, Hs 833, interferon stimulated protein,, pane, lung, blad, breast, cerv, ovar, headnk, esoph, mela, CTL+s m
413324, V00571, Hs 75294, corticotropin releasing hormon, blad, diag
413385, M34455, Hs 840, indoleamine pyrrole 2,3 dioxyg, blad, lung, mela, fibro, uter, sarc, s m 413554, AA319146, Hs 75426, secretogranin II (chromogranin, pane, glio, diag
413719, BE439580, Hs 75498, small inducible cytokine subfa, leuk, pane, lung, headnk, cerv, colon, uter, stom, esoph, diag
414555, N98569, Hs 76422, phospholφase A2, group IIA (p, pros, s m
414577, AI056548, Hs 378938 hypothetical protein FU20992 , angio, CTL+diag 4W74, X02419, Hs 77274, plasminogen activator, urokma, lung, blad, headnk, pane, stom ovar, esoph, diag 414812, X72755, Hs 77367, monokine induced by gamma inte, breast, blad, lung, fibro, pane, colon, headnk cerv, stom, renal, ovar, test, mela, esoph, diag
414883, AA926960, Hs 348669, CDC28 protein kinase 1, lung, ovar, stom, colon, cerv, headnk, test, s m
414907, X90725, Hs 77597, polo (Drosophia) like kinase, blad, lung, ovar, test s m
414991, C17898, , Homo sapiens up-regulated by B, fibro, lung, mAb+diag
415138, C18356, Hs 295944, tissue factor pathway inhibito, angio, pane, stom, lung, uter, CTL+diag 415539, AI733881 , Hs 72472, NAME OMITTED receptor kinase breast, mAb+s m
415668, AW957684, Hs 306814, Homo sapiens lysyl oxidase Ilk, mela, diag
415669, NMJ05025, Hs 78589, seπne (or cysteine) proteinas, lung, mAb+diag+s m
415817, U88967, Hs 78867, protein tyrosine phosphatase, , lung, glio, headnk, cerv, mela, esoph, fibro, mAb+s m
415929, AA724373, Hs 304950, Homo sapiens mucolιpιn-3 (MCOL, mela, mAb 416091, AF295370, Hs 283082, defeπsin, beta 3, headnk, esoph, mela, CTL+diag
416209, AA236776, Hs 79078, MAD2 (mitotic arrest deficient, lung, headnk, colon, uter, stom, CTL+s m
416250, AA581386, Hs 73452, Kremen 2, esoph, lung, cerv, ovar, mAb+s
416530, U62801, Hs 79361, kallikrein 6 (neurosin, zyme), ovar, uter; diag
416636, N32536, Hs 42645, solute earner family 16 (mono, breast, pane, uter, mela, mAb+s m 416658, U03272, Hs 79432, fibnllin 2 (congenital contra, lung, ovar, uter, blad, angio, test, sarc, diag
416836, D54745, Hs 80247, cholecystokinin, pros, EWS, glio , diag
416857, AA188775, Hs 292453, FGENESH predicted TM contaiπin, glio, mAb+s m
416965, N26223, Hs 160436, MDAC1, fibro, ovar, uter, mAb
417034, NM_006183, Hs 80962, neurotensin, lung, headnk, cerv, diag 417079, U65590, Hs 81134, interleukin 1 receptor aπtagon, blad, lung, headnk, cerv, esoph, diag
417166, AA431323, Hs 42146, Paired box protein Pax-3, mela sarc, CTL
417389, BE260964, Hs 82045, idkine (neunte growth promot, ovar, lung, blad, uter, cerv, pane, stom, mela, test, colon, sarc, mAb+diag
417433, BE270266, Hs 82128, 5T4 oncofetal trophoblast glyc, pane, breast blad, lung, headnk, cerv, uter, ovar, stom, renal, mAb
417771, AA804698, Hs 82547, retinoic acid receptor respond blad, cerv, pane, pros, ovar; mAb 417866, AW067903, Hs 82772, collagen, type XI, alpha 1, lung, pane, breast, ovar, headnk, stom, sarc, CTL
417931, W95642, Hs 82961, trefoil factor 3 (intestinal), ovar, pane, stom, colon, uter, pros, diag
417933, X02308, Hs 82962, thymidylate synthetase, blad, lung, angio, colon, pane, esoph, s m
418007, M13509, Hs 83169, matnx metalloproteinase 1 (in, lung, blad, fibro, headnk, pane, stom, colon, ovar, esoph, mela, mAb+diag+s
418030, BE207573, Hs 83321 , neuromedin B, glio, pane, diag 418064, BE387287, Hs 83384, S100 calcium binding protein, , mela, diag
418281, U09550, Hs 1154, oviductal glycoprotein 1, 120k, uter, ovar; CTL+diag
418478, U38945, Hs 1174, cyclin-depeπdeπt kinase mhibi, lung, blad, ovar, headnk, pane, cerv, mela, sarc, s m
418506, AA084248, Hs 372651, Unknown protein for MGC 29643 , angio, ovar, glio, uter, lung, blad, pane, mela, sarc, mAb+diag
418526, BE019020, Hs 85838, solute earner family 16 (mono, lung, blad, renal, pane, stom, colon, ovar; mAb+s m 418558, AW082266, Hs 86131, Fas (TNFRSF6)-assocιated viad, esoph, headnk, s m
418678, NM_001327, Hs 87225, cancer/testis antigen (NY-ESO-, lung, blad, stom, ovar, pane, esoph cerv, sarc, CTL
418738, AW388633, Hs 6682, solute earner family 7, (cab, angio, lung, ovar, blad, colon, stom, pane, uter, leuk, mAb+s m
418830, BE513731, Hs 348874, hypothetical protein MGC4816, lung, CTL
418867, D31771, Hs 89404, msh (Drosophila) homeo box horn, blad, s m 418870, AF147204, Hs 89414, chemokine (C-X-C motif), recep, leuk, ovar, breast, blad, renal, mAb+s m
419080, AW150835, Hs 18878, hypothetical protein FU21620, renal, lower uter, lung, CTL
419121, AA374372, Hs 89626, parathyroid hormone-like hormo, lung, esoph, headnk, blad, diag
419171, NM_002846, Hs 89655, protein tyrosine phosphatase, , lung, mAb+s m
419172, AW338625, Hs 22026, ESTs, similar to TRANSMEMBRAN, angio, renal, mAb+s m 419183, U60669, Hs 89663, cytochrome P450, subfamily XXI, blad, lung, headnk, pane, CTL+s m
419216, AU076718, Hs 164021, small inducible cytokine subfa, pane, lung, stom, cerv, pros, headnk, esoph, diag
419235, AW470411 , Hs 288433, neurotπmiπ, pane, fibro, headnk, lung, mAb+diag
419452, U33635, Hs 90572, PTK7 protein tyrosine kinase 7, ovar, pros, lung, breast, uter, test, pane, stom, sarc, mAb+s m
419508, AW997938, Hs 90786, ATP-binding cassette, sub-fami, glio, omuo, stom, lung, pane, colon, renal, uteπ mAb+s m 419556, U29615, Hs 91093, chrtjπase 1 (chitotπosidase), lung, fibro, test, mAb+diag
419704, AA429104, Hs 45057, ESTs, glio, CTL+s m
419723, AL120193, Hs 339810, longevity assurance (LAG1, S , glio, mAb+diag
419741, NMJ07019, Hs 93002, ubiquitin earner protein E2-C, blad, lung, colon, ovar, test, esoph, mela sarc, CTL+s m
419833, AA251131 , Hs 220697, Homo sapiens tryptophanyl-tRNA, fibro, stom, blad, esoph, uter; drag 420159, AI572490, Hs 99785, Homo sapiens cDNA FU21245 ti, blad, stom, mAb
420162, BE378432, Hs 95577, cyclin-dependent kinase 4, lung, mela, sarc, s m
420370, Y13645, Hs 97234, uroplakiπ 2, blad, mAb
420440, NMJ302407, Hs 97644, mammaglobin 2, ovar, uter, cerv, diag
420602, AF060877, Hs 99236, regulator of G-protein signall, headnk, glio, cerv, mela, CTL+s 420610, AI683183, Hs 99348, distal less homeo box 5, uter, endo, lung, CTL
420737, L08096, Hs 99899, CD70 , tumor necrosis factor , renal, mAb+s m
420876, AA918425, Hs 177744, FGENES predicted novel protein, pane, blad, s m
421066, AU076725, Hs 101408, branched chain aminotransferas, blad, lung, CTL+s m
421110, AJ250717, Hs 1355, cathepsin E, blad, pane, stom, lung, fibro, ovar, esoph, sm+diag 421340, F07783, Hs 1369, decay accelerating factor for , angio, pane, stom, diag
421379, Y15221, Hs 103982, small inducible cytokine subfa, breast, pane, headnk, lung, stom, blad, cerv, colon, leuk, fibro, test, mela, esoph, diag
421471, U90545, Hs 327179, solute earner family 17 (sodi, renal, mAb+s m
421474, U76362, Hs 104637, solute earner family 1 (gluta, lung, mAb+s m
421524, AA312082, Hs 105445, GDNF family receptor alpha 1, breast, mAb+s m 421552, AF026692, Hs 105700, secreted frizzled related prot breast, ovar, pane, cerv, uter, pros, lung, stom, headnk, diag
421563, NMJ06433, Hs 105806, granulysin, fibro, diag
421574, AJ000152, Hs 105924, defensin, beta 2, headnk, lung, CTL+diag
421582, AI910275, Hs 350470, trefoil factor 1 (breast cance, breast pane, lung o uc, diag 421659, NMJ14459, Hs 106511, protocadheπn 17, fibro, mAb 421753, BE314828, Hs 107911, ATP-binding cassette, sub-fami, lung, mAb+s m 421817, AF146074, Hs 108660, ATP-binding cassette, sub-fami, lung, cerv, headnk, blad, mAb+s m 421829, AB018330, Hs 108708, calcium/calmodulin-dependent p, pros, s m 422048, NM_012445, Hs 288126, spondm 2, extracellular matπ, pane pros sarc, diag
422083, NMJ01141, Hs 111256, arachidonate 15-lιpoxygenase, , pros, s m 422109, S73265, Hs 1473, gastπn releasing peptide, pane, lung, colon, fibro, diag 422158, L10343, Hs 112341, protease inhibitor 3, skin der, headnk, blad, lung, cerv, stom, esoph, diag 422192, AA305159, Hs 113019, fls485, mela, s m 422260, AA315993, Hs 105484, regenerating gene type IV, colon, omuc, stom, pane, mAb+diag
422282, AF019225, Hs 114309, apolipoprotein L, blad lung, headnk, renal, diag
422283, AW411307, Hs 114311, CDC45 (cell division cycle 45„ lung, blad, test, cerv, headnk, esoph, s m 422330, D30783, Hs 115263 epiregulm, pane, colon, blad, mAb+diag
422397, AJ223366, Hs 116051 , MYEOV Myeloma overexpressed ge, pane, stom, colon, esoph, renal, blad, CTL+s m 422424, AI186431, Hs 296638, prostate differentiation facto, blad, pane, pros, angio, colon, stom, lung mela diag
422578, AF239666, Hs 1545, caudal type homeo box traπscπ, colon, CTL
422627, BE336857, Hs 118787, transforming growth factor, be, colon, renal, sarc, mAb+diag
422765, AW409701, Hs 1578, baculoviral IAP repeat-contain, lung, blad, s m
422809, AK001379, Hs 121028, hypothetical protein FU10549, blad, cer, lung, uter, angio, stom, test, s m 422867, L32137, Hs 1584, cartilage oligomeπo matnx pr, breast, ovar, pros, pane, lung, colon, uter, sarc, diag
422956, BE545072, Hs 122579, ECT2 protein (Epithelial cell , ovar, blad, pane, lung, headnk, colon.sto CTL+s m
423161, AL049227, Hs 124776, downstream of cadhenn 6 (by 3, renal, ovar, blad, mAb+s m
423184, NM M4428, Hs 1624, ephππ A1, pros, pane, renal.colon, mAb+s m
423242, AL039402, Hs 125783, DEME-6 protein, breast, renal, ovar, pros, colon, CTL 423508, AW604297, Hs 129711, hepatitis A virus cellular reo, renal, colon, mAb
423583, AL122055, Hs 129836, KIAA1028 protein, pros, s m
423634, AW959908, Hs 1690, hepaπn-binding growth fxtor , lung, blad, headnk, pane, diag
423673, BE003054, Hs 1695, matnx metalloprotemase 12 (m, blad, lung, headnk, ovar, pane, colon, stom uter, cerv, esoph test mAb+diag+s m
423936, U77629, Hs 135639, achaete-scute complex (Drosoph, colon, stom, ovar; CTL 423961, D13666, Hs 136348, peπostin (OSF-2os) breast, colon, blad, lung, fibro, pane, headnk, ovar, mela, sarc, mAb+diag
424008, R02740, Hs 137555, putative chemokine receptor, G, blad, headnk, stom, cerv, esoph, mAb+s m
424046, AF027866, Hs 138202, senne (or cysteine) proteinas, headnk, lung, cerv, diag
424321, W74048, Hs 1765, lymphocyte-specific protein ty, mela fibro, s m
424381, AA285249, Hs 146329, protein kinase Chk2 (CHEK2), lung, colon, test, s m 424411 , NM_005209, Hs 146549, crystallin, beta A2, pane, sarc, s m
424502, AF242388, Hs 149585, lengsin, lung, s m
424503, NM_002205, Hs 149609, integπn, alpha 5 (fibronectin, pane, pros.angio, blad, lung, mAb+s m 424620, AA101043, Hs 151254, kallikrein 7 (chymotryptic, st, ovar; diag
424687, J05070, Hs 151738, matnx metalloprotemase 9 (ge, headnk, pane, lung, blad, uter, cerv, colon, stom, test, mela, sarc, diag 424735, U31875, Hs 272499, short-chain alcohol dehydrogen, blad, breast, CTL+s m
424825, AF207069, Hs 153357, procollagen lysine, 2-oxogluta, mela CTL+s m
424905, NM_002497, Hs 153704, NIMA (never in mitosis gene a), ovar, blad, lung, headnk, pane, stom, s m
424917, AI636208, Hs 96901 , hypothetical protein FLJ23049, fibro, uter, ovar, CTL
424943, AU077260, Hs 153924, death-associated protein kinas, fibro, s m 425009, X58288, Hs 154151, protein tyrosine phosphatase, , renal, fibro, mAb+s m
425071, NM_013989, Hs 154424, deiodinase, lodothyronme, typ, pros, colon, stom, uter, cerv, headnk, esoph, pane, diag
425115, R44664, Hs 123956, downstream of G protein-coup, glio, mAb+s m
425247, NM_005940, Hs 155324, matnx metalloprotemase 11 (s, breast, ovar, lung colon, pane, headnk, stom, uter, cerv, blad, esoph, sarc, mAb+diag+s m
425263, NM_001197, Hs 155419, BCL2-ιnteraotιng killer (apopt, pros, s m 425322, U63630, Hs 155637, protein kinase, DNA-actιvated„ lung, headnk, s m
425535, AB007937, Hs 158287, syndecan 3, mela, glio, mAb+s
425650, NM_001944, Hs 1925, desmoglein 3 (pemphigus vulgar, lung, headnk, cerv, esoph, blad mAb
425721, AC002115, Hs 159309, uroplakin 1A, blad, mAb
425723, NM_014420, Hs 159311, diekkopf (Xenopus laevis) homo, endo, uter, colon, CTL+diag 425734, AF056209, Hs 159396, peptidylglycme alpha-amidatin, lung, s m
425776, U25128, Hs 159499, parathyroid hormone receptor 2, ovar, uter, lung, mAb+diag
425842, AI587490, Hs 159623, NK-2 (Drosophila) homolog B, pane, glio, s m
425852, AK001504, Hs 159651, death receptor 6, TNF superfam, blad, lung, headnk, mAb+s m
425883, AL137708, Hs 161031, Homo sapiens mRNA, cDNA DKFZp4, blad, pane, mAb 425998, AU076629, Hs 165950, fibroblast growth factor recep, renal, mAb+s m
426028, NM_001110, Hs 172028, a disintegπn and metalloprote, blad, mAb+diag
426215, AW963419, Hs 155223, stanniocalcin 2, breast lung, renal, colon, ovar, uter; mAb+diag
426227, U67058, Hs 154299, Human proteinase activated rec, pane, lung, colon, esoph, stom, mAb+s m
426322, J05068, Hs 2012, traπscobalamin I (vitamin B12 , pane, blad, stom, diag 426344, H41821, Hs 322469, transcπptional activator of t glio, CTL+s
426427, M86699, Hs 169840, TTK protein kinase, ovar, lung, headnk, cerv, colon, uter, stom, test, CTL+s m
426451, AI908165, Hs 169946, GATA binding protein 3 (T-cell, blad, breast, s m
426514, BE616633, Hs 170195, bone morphogenetic protein 7 (, ovar, colon, blad, lung, cerv, mAb+diag
426600, NMJ03378, Hs 171014, VGF nerve growth factor induci, mela, sarc, diag 426761, AI015709, Hs 172089, PORIMIN Prc-oncosis receptor i, lung, esoph, pros, uter, pane, colon, ovar, headnk, mAb+s m
426812, AF105365, Hs 172613, solute earner family 12 (pota, renal, mAb+s m
426890, AA393167, Hs 41294, ESTs, renal, colon, ovar, uter, stom, CTL
427239, BE270447, Hs 356512, ubiquitin earner protein, lung, blad, test, mela, sarc, CTL+s m
427335, AA448542, Hs 278444, G antigen 7B, lung, headnk, blad, mela, esoph, sarc, CTL 427343, AI880044, Hs 176977, protein kinase C binding prate, glio, CTL+s m
427722, AK000123, Hs 180479, hypothetical protein FLJ20116, colon, stom, pane, CTL
427747, AW411425, Hs 180655, seπne/threoniπe kinase 12, blad, lung, ovar, stom, test, esoph, sarc, s m
427923, AW274357, Hs 301406, FGENESH predicted 11 TM pratei, mela, mAb
427969, NM_001963, Hs 2230, epidermal growth factor (beta-, pane, mAb+diag 428093, AW594506, Hs 104830, ESTs, ovar, pane, CTL
428179, AI127772, Hs 380877, serum/glucocorticoid regulated, breast, s m
428187, AI687303, Hs 285529, G protein-coupled receptor 49, ovar, uter, colon, stom, mAb+s m
428242, H55709, Hs 2250, leukemia inhibitory factor (ch, ovar, pane, leuk, lung, diag 428296, NMJ03058, Hs 183572, solute earner family 22 (orga, renal, mAb+s m
428330, L22524, Hs 2256, matnx metalloprotemase 7 (ma, uter, ovar, fibro, pros, pane, lung, blad, headnk, esoph, mela, mAb+diag+s m
428368, BE440042, Hs 83326, matnx metalloprotemase 3 (st, headnk, stom, esoph, colon, diag
428392, H10233, Hs 2265, secretory granule, neuroeπdocr, pane, diag 428450, NM_014791, Hs 184339, KIAA0175 gene product, ovar, cerv, pane, lung, blad, mela, s
428479, Y00272, Hs 334562, cell division cycle 2, G1 to S, lung, blad, colon, uter, ovar, s m
428484, AF104032, Hs 184601, solute earner family 7 (catio, lung, blad, headnk, cerv, esoph, glio, uter, stom, colon, mela, mAb+s m
428486, AW583497, Hs 184604, pancreatic polypeptide, pane, diag
428505, AL035461 , Hs 2281 , chromogranin B (seeretogranin , pane, lung, diag 428513, BE220806, Hs 184697, plexin C1, mela, pane, breast stom, headnk mAb
428579, NM M5756, Hs 184942, G protein-coupled receptor 64, ovar, EWS, uter; mAb+s m
428664, AK001666, Hs 189095, similar to SALL1 (sal (Drosoph, blad, ovar, pros, lung, stom, test, CTL+s m
428698, AA852773, Hs 334838, KIAA1866 protein, breast, colon, lung, pane, stom, headnk, ovar, EWS, mAb
428748, AW593206, Hs 98785, Ksp37 protein, lung sarc, diag 428758, AA433988, Hs 98502, CA125 antigen, mucin 16, ovar, cerv, lung, pane, stom, renal, diag
428778, AK000530, Hs 193326, fibroblast growth factor reoep, ovar, mAb+s m
428953, AA306610, Hs 348183, tumor necrosis factor receptor; cerv, pane, colon, stom, headnk, renal, mAb+diag
428969, AF120274, Hs 194689, artemin, lung, cerv, diag
428970, BE276891, Hs 194691, retinoic acid induced 3 (RAIG, stom, pane, colon, ovar, fibro, mAb+s m 429149, AW193360, Hs 197962, Homolog of mouse ADP-πbosylat, glio, mAb+s m
429211, AF052693, Hs 198249, gap junction protein, beta 5 (, lung, blad, headnk, cerv, esoph, stom, mela, mAb+s
429263, AA019004, Hs 198396, ATP binding cassette, sub-fami, lung, mAb+s m
429276, AF056085, Hs 198612, G protein-coupled receptor 51, angio, blad, glio, mAb+s m
429353, AL117406, Hs 335891 , ATP-binding cassette transport, breast, pros , mAb+s m 429547, AW009166, Hs 99376, FGENESH predicted novel secret, pane, headnk, lung, ovar, diag
429610, AB024937, Hs 211092, LUNX protein, PLUNC (palate lu, lung, fibro, mAb+diag
429903, AL134197, Hs 93597, cyclin dependent kinase 5, reg, lung, mela, s m
429910, NM_000867, Hs 2507, 5-hydroxytryptamιne (serotonin, leio, mAb+s
430147, R60704, Hs 234434, hairy/enhancer-of split relate, glio, s m 430178, AW449612, Hs 152475, 3 UTR of achaete scute comple, colon, stom, ovar; CTL
430377, NMJ01922, Hs 301865, dopachrome tautomerase (dopach, mela, CTL
430413 AW842182, Hs 241392, small inducible cytokine A5 (R, fibro, esoph, mela diag
430486, BE062109, Hs 241551, chloπde channel, calcium ach, lung, blad, headnk, cerv, esoph, mAb+s m
430822, AJ005371, Hs 248017, glyceraldehyde-3-phosphate deh, mela, sarc, s m 431130, NM_006103, Hs 2719, HE4, epididymis specific, whey, ovar, uter, diag
431462, AW583672, Hs 256311, gramn like neuroendocπne pep, pane, lung, glio, test, diag
431515, NM_012152, Hs 258583, EDG-7 (endothelial different!, ovar, pros, lung, blad, mAb+s m
431620, AA126109, Hs 264981, 2'-5'-olιgoadenylate synthetas, esoph, cerv, CTL+s m
431629, AU077025, Hs 265827, interferon, alpha-mducible pπ pane, uter, cerv, stom, esoph, mela, mAb+diag 431630, NM 002204, Hs 265829, integπn, alpha 3 (antigen CD4, ovar, pane, blad, headnk, mela, renal, mAb+s m
431745, AW972448, Hs 163425, Novel FGENESH predicted cadhen fibro, ovar, uter; mAb
431840, AA534908, Hs 2860, POU domain, class 5, transcnp, test, renal, blad, CTL
431846, BE019924, Hs 271580, uroplakin 1B, lung, blad, headnk, uter, cerv, stom, ovar, mAb+diag
431958, X63629, Hs 2877, cadhenn 3, type 1, P-oadheπn, lung, blad, cerv, headnk, ovar, colon, pros, pane, breast, esoph, test, mela, mAb+diag 432101, AI918950, Hs 123642, EphA3, pros, pane, EWS sarc, s
432179, X75208, Hs 2913, EphB3, ovar, colon, mAb+s m
432196, AW300888, Hs 273230, hypothetical protein FU10830, renal, CTL
432201, AI538613, Hs 298241, Transmembrane protease, seπne, breast colon, ovar, stom, pane uter, cerv, lung , mAb+diag+s m
432579, AF043244, Hs 278439, nucleolar protein 3 (apoptosis, renal, CTL 432596, AJ224741, Hs 278461, matπlin 3, pane, breast, sarc, diag
432606, NM_002104, Hs 3066, granzyme K (senne protease, g, renal, breast, lung, stom, hepC, fibro, leuk, CTL
432829, W60377, Hs 57772, ESTs, blad, CTL+s m
432874, W94322, Hs 279651, melanoma inhibitory activity, pane, stom, mela, sarc, diag
432990, AL036071 , Hs 279899, tumor necrosis factor receptor; pros, renal, mAb+s 433001, AF217513, Hs 279905, clone HQ0310 PRO0310p1, colon, breast lung, blad, cerv, uter, test mela, s m
433447, U29195, Hs 3281, neuronal pentraxin II, mela, esoph, colon, renal, diag
433848, AF095719, Hs 93764, carboxypeptidase A4, headnk, esoph, lung, s m
433867, AK000596, Hs 3618, hippoealoin like 1, renal, CTL
434206, AW136973, Hs 362915, ESTs, Weakly similar to S69890, colon, lung, stom, CTL+s m 434276, AF123659, Hs 93605, leucine zipper, putative tumor; mela, s m
434293, NM_004445, Hs 3796, EphB6, blad, pros, s m
435013, H91923, Hs 110024, NM_020142 Homo sapiens NADH ub, renal, lung, sarc, CTL
435472, AW972330, Hs 283022, tnggeπng receptor expressed , glio, mAb
435505, AF200492, Hs 211238, ιnterieukιn-1 homolog 1, lung, headnk, drag 436456, AW292677, Hs 248122, melanin-concentrating hormone , mela, glio, mAb+s m
436480, AJ271643, Hs 87469, putative acid-sensing ion chan, glio, mAb+s m
436481, AA379597, Hs 5199, HSPC150 protein similar to ubi, lung, blad, colon, ovar, uter, headnk, test, s m 436576, A1458213, Hs 77542, ESTs, renal, pane, headnk, lung, mAb+s m
436608, AA628980, Hs 192371, down syndrome cπtioal region , blad, lung, sarc, CTL+s 436895, AF037335, Hs 5338, carbonic anhydrase XII, breast, renal, ovar, glio, mAb+s m
436961, AW375974, Hs 156704, ESTs, lung, pane, renal, uter, colon , CTL
436982, AB018305, Hs 5378, spondiπ 1, (f-spondin) extrace, ovar, fibro, diag
437016, AU076916, Hs 5398, guanine monphosphate synthetas, lung, blad, cerv, esoph, colon, headnk, s m
437044, AL035864, Hs 69517, differentially expressed in Fa, headnk, cerv, lung, blad, breast, pros, ovar, stom, esoph, CTL 437789, AI581344, Hs 127812, ESTs, Weakly similar to T17330, lung, CTL
437852, BE001836, Hs 256897, putative GPCR, blad, lung, mAb+s m
438380, T06430, Hs 6194, chondroitin sulfate proteoglyc, glio, mela, diag
438549, BE386801, Hs 21858, tπnucleotide repeat contamin, mela, sarc, CTL+diag
439018, AW300887, Hs 26638, membrane-spanning 4-domaιπs, s, uter, stom, pros, fibro, mAb 439223, AW238299, Hs 250618, UL16 binding protein 2, lung, headnk, cerv, esoph, leuk, blad, colon, mAb
439477, W69813, Hs 58042, ESTs, Moderately similar to GF, lung, mAb+s m
439569, AW602166, Hs 222399, CEGP1 protein, breast, pros, blad, diag
439606, W79123, Hs 58561, G protein-coupled receptor 87, lung, blad, headnk, cerv, esoph, mAb+s 439738, BE246502, Hs 9598, sema domain, immunoglobulin do, blad, lung, cerv, renal, mAb+s m 439979, AW600291, Hs 6823, hypothetical protein FLJ10430, renal, cerv, pros, headnk, colon, test sarc, mAb 440006, AK000517, Hs 6844, NALP2 protein, PYRIN Containin, blad, ovar, lung, headnk, test, s m 440065, W03476, Hs 266331 , Homo sapiens Fc receptor homol, mela diag 440304, BE159984, Hs 125395, hepatitis A virus cellular rec, renal, colon, blad, mAb+s m
440516, S42303 Hs 161, cadhenn 2, type 1, N cadhenn glio, ovar, uter, renal, hepC, mAb+diag 440672, AF083811, Hs 7345, MAD1 (mitotic arrest deficient, mela, s m
441362, BE614410, Hs 23044, RAD51 (S cerevisiae) homolog , lung, blad, headnk, test, mela, esoph, s m 442117, AW664964 Hs 128899, ESTs, hypothetical protein for; breast, lung, blad, pane, headnk, stom, ovar, pros, sarc, mAb+s m 442133, AW874138 Hs 129017, ESTs, type la transmembrane p, ovar, uter; mAb
442275, AW449467, Hs 54795, Homo sapiens secretoglobin, fa, fibro, diag 442652, AI005163, Hs 201378, Homo sapiens cDNA FLJ40427 fis, fibro, ovar, uter, CTL 443105, X96753, Hs 9004, chondroitin sulfate proteoglyc, mela, mAb+diag 443247, BE614387, Hs 333893, c Myc target JP01, colon, lung, blad, pane, CTL 443324, R44013, Hs 164225, ESTs, fibro, mAb+diag
443426, AF098158, Hs 9329, chromosome 20 open reading fra colon, lung, blad, stom test, mela sarc, CTL 443595, AF169312, Hs 9613, PPAR(gamma) angiopoietin relat, renal, drag 443646, AI085198, Hs 164226, Thrombospoπdin 1, angio, pane, uter; diag 443859, NM_013409, Hs 9914, follistatin, lung cerv, headnk, blad, esoph, diag 443987, AW163123, Hs 10071, seven transmembrane protein TM, renal, mAb+s m
444006, BE395085 Hs 334762, type I transmembrane protein F, pane, colon, lung ovar, renal, esoph, mela blad, stom cerv, mAb 444090, S69115, Hs 10306, natural killer cell group 7 se, fibro, renal, mela, drag 444371, BE540274, Hs 239, forkhead box M1, lung, headnk, blad, glio, test, mela, s m
444381, BE387335, Hs 283713, hypothetical protein BC014245, breast, colon, blad, lung, pane, headnk, ovar, stom, uter, renal, angio, test, mela, esoph, sarc, CTL+diag 444488, AW192879, Hs 355660, ancient conserved domain prate, renal, mAb+s m
444527, NM_005408, Hs 11383, small inducible cytokine subfa, fibro, esoph, drag 444781, NM_014400, Hs 11950, GPI-anchored metastasis-associ, lung, blad, headnk, cerv, mAb+diag
444783, AK001468, Hs 62180, anillin (Drasophila Scraps hom, ovar, lung, blad, headnk, pane, cerv, stom uter, colon, esoph, CTL+s m 445417, AK001058, Hs 12680, a disintegnn like and metallo, pane, headnk, stom, lung, esoph, sarc, colon, diag 445537, AJ245671, Hs 12844, EGF-like-domam, multiple 6, ovar, blad, uter, breast, lung, headnk renal, fibro, pane, cerv, sarc, mAb+diag 445891, AW391342 Hs 199460, DPCR1 protein, stom, pane, esoph, omuc, esoph mAb 445895, D29954, Hs 13421, KIAA0056 protein, pros, CTL 446051, BE048061, Hs 37054, ephrm A3, colon, breast, mAb+diag 446163, AA026880, Hs 25252, prolactin receptor, breast, cerv, uteπ mAb+s m 446341, AL040763, Hs 310735, FGENESH prediction similar to , mela, mAb+s m
446619, AU076643, Hs 313, secreted phosphoprotein 1 (ost, ovar, fibro, pane, headnk, lung, colon, blad, mela, esoph, uter, sarc, drag 446650, AB016625, Hs 15813, solute earner family 22 (orga, renal, mAb+s m 446921, AB012113, Hs 16530, small inducible cytokine subfa, breast, pane, headnk, lung, fibro, mela, drag 447033, AI357412, Hs 157601, Predicted gene Eos cloned, se, colon, pros, fibro, breast, ovar, lung, pane, sarc, CTL+diag 447072, D61594, Hs 17279, tyrosylprotein sulfotraπsferas, glio, pane, CTL+s m
447131, NMJ304585, Hs 17466, retinoic acid receptor respond, renal, breast, stom lung, mela, ovar, mAb+s m 447208, BE315291, Hs 237971, hypothetical protein MGC5627, esoph, stom, colon, CTL+diag 447269; NM_004861, Hs 17958, cerebroside (3'-phosphoadenyly; renal, CTL
447342, AI199268, Hs 19322, Homo sapiens, Similar to RIKEN, colon, blad, pros, lung, stom, ovar; CTL 447400, AK000322, Hs 18457, hypothetical protein FLJ20315, colon, pros, stom, uter, mAb+diag
447674, BE270640, Hs 19192, cyclin-dependent kinase 2, mela, s m
448243, AW369771, Hs 367688, integππ, beta 8, ovar, uter, lung, stom, headnk, glio, pane , mAb+s m
448610, NM_006157, Hs 21602, nel (chicken) like 1, mela, sarc, diag
448733, NM_005629, Hs 187958, solute earner family 6 (neuro, lung, renal, mAb+s m 448844, AI581519, Hs 177164, FGENESH predicted novel cell s, pane, lung, stom, omuc, mAb+s m
449032, AA045573, Hs 22900, nuclear factor (erythroid-deπ, colon, test, stom, CTL+s m
449048, Z45051, Hs 22920, similar to S68401 (cattle) glu, pane, ovar, uter, glio, headnk, lung, sarc, mAb
449444, AW818436, Hs 351306, solute earner family 16 (mono, renal, pane, mAb+s m
449523, NMJJ00579, Hs 54443, chemokine (C-C motif) receptor, lung, pane, renal, stom, hepC, fibro, leuk, mela, mAb+s m 449720, AA311152, Hs 288708, hypothetical protein FU21562, colon, CTL
449722, BE280074, Hs 23960, cyclm B1, headnk, blad, lung, pane, angio, test, mela, esoph, s m
450001, NM_001044, Hs 406, solute earner family 6 (neuro, renal, mAb+s m
450375, AA009647, Hs 352537, a disintegnn and metalloprote, breast ovar, headnk, pane, lung, esoph, colon, sarc, mAb+diag+s m
450531, AW301032, Hs 203800, (BC017500) Similar to hypothet, colon, CTL 450701, H39960, Hs 288467, hypothetical protein XP 098151, lung, headnk, pane, breast stom, ovar, esoph, colon, sarc, mAb+diag
450726, AW204600, Hs 355462, HUMPSPBA Human pulmonary surfa, fibro, lung, s m
450931, N25156, Hs 25648, tumor necrosis factor receptor, lung, renal, mAb+s m
450983, AA305384, Hs 25740, ER01 (S cerevιsιae)-lιke, blad, lung, ovar, pane, diag
451310, AW250651, Hs 26213, Human DNA sequence from clone , colon, pane, CTL 451527, AF022813, Hs 26518, transmembrane 4 superfamily me, renal, mAb
451537, R56631, Hs 26550, retinoid X receptor, gamma, mela, CTL+s m
451668, Z43948, Hs 326444, cartilage acidic protein 1, blad, ovar, lung, mAb+diag
451939, U80456, Hs 27311, single-minded (Drasophila) hom, pros, CTL
451979, F06972, Hs 27372, endothelial tyrosine kinase (E, angio, CTL+s m 451988, AF263928, Hs 27410, papillomavirus regulatory fact, renal, CTL
452017, AF109302, Hs 27495, prostate cancer associated pro, pros, s m
452097, AB002364, Hs 27916, a disintegnn like and metallo, ovar, mAb+s m +dιag
452190, H26735, Hs 91668, Homo sapiens clone PP1498 unkn, breast, stom, pane, mAb
452194, AI694413, Hs 373599 olfactory receptor, family 2, , stom, pane, renal, colon, mela fibro, mAb+s m 452203, X57522, Hs 352018, transporter 1, ATP-biπdmg cas, cerv, esoph, blad, stom, mela, renal, mAb+s m
452281, T93500, Hs 28792, Homo sapiens cDNA FLJ11041 fis, breast, headnk, pane, stom, lung, esoph, fibro, diag
452401, NM_007115, Hs 29352, tumor necrosis factor, alpha-i, blad, breast pane, headπk.stom, lung, leuk, renal, esoph, diag
452431, U88879, Hs 29499, toll-like receptor 3, renal, hepC, mAb
452747, BE153855, Hs 61460, Ig superfamily receptor LNIR, breast, blad, lung, headnk, ovar, stom, uter, pane, mAb 452838, U65011, Hs 30743, preferentially expressed antig, lung, ovar, breast, mela, test, esoph, renal, sarc, CTL
452862, AW378065, Hs 8687, ADAMTS2 (a disintegnn like a, headnk, breast colon, leuk, lung, blad, esoph, stom, sarc, mAb+diag
453195, BE241876, Hs 32352, hypothetical protein DKFZp434K, renal, CTL
453496, AA442103, Hs 33084, solute earner family 2 (facil, renal, pros, mAb+s m 453837, AL138387, Hs 256126, baculoviral IAP repeat-contain, renal, mela, sarc, s m 453968, AA847843, Hs 62711, High mobility group (nonhiston, lung, uter, blad, test, CTL+s m 456546, AI690321, Hs 203845, KCNK15 potassium channel, subf; ovar , mAb+s m 456662, NMJ02448, Hs 1494, msh (Drasophila) homeo box hom, uter, ovar , CTL 457133, M54968, Hs 351221, v-Kι-ras2 irsten rat sarcoma , pane, s m 457489, AI693815, Hs 127179, cryptic gene, pane, pros, lung, drag 457819, AA057484, Hs 35406 FLJ20522 Hypothetical protein , lung, cerv, headnk, mAb+diag 458079, AI796870, Hs 381220 Homo sapiens similar to RIKEN , mela, fibro, sarc, mAb 458627, AW088642, Hs 97984, SRY (sex determining region Y), ovar, uter, test CTL
TABLE 2B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT Number Accession
414991 1785136J D78831 C17898 D78863
TABLE 2C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I etal , Nature (1999) 402489-495
Strand Indicates DNA strand from which exons were predicted N positon Indicates nucleotide positions of predicted exons
Pkey Ref Strand Nt_posιtιon
400843 9188605 Plus 5863-5970,7653-7784,8892-9023,9673-9807,
402075 8117407 Plus 121907-122035,122804-122921,124019-12416
402901 8894222 Minus 175426-175667
404287 2326514 Plus 53134-53281
404682 9797231 Minus 40977-41150
404875 9801324 Plus 96588-96732,97722-97831
404977 3738341 Minus 43081-43229
405033 7107731 Minus 142358-142546
406400 9256298 Plus 1553-1712,1878-2140,42524385,5922-6077
Table 3A Disease Indications and Preferred Utilities for Selected Genes
Table 3A provides preferred disease indications and preferred utilities for about 2709 selected genes These genes were identified using Eos/Affymetnx Genechip arrays
Pkey Unique Eos probeset identifier number ExAccn Exemplar Accession number UnigenelD Unigene ID number Unigene Title Unigene gene title Disease preferred diseases indicated for selected gene as descπbed in table 1 and abbreviated as follows blad (bladder diseases), angio (blood vessel diseases), EWS
(bone diseases), glio (brain diseases), breast (breast diseases), cerv (cervical diseases), colon (colorectal diseases), esoph (esophageal diseases), fibro (fibrosis diseases), headnk (head & neck diseases), leio (leiomyoma diseases), leuk (leukocyte diseases), hepC (liver diseases), lung (lung diseases), ovar (ovanan diseases), endo (ovanan endometnoid diseases), omuo (ovanan mucinous diseases), pane (pancreatic diseases), pros (prostate diseases), renal (renal diseases), sarc (soft tissue and bone diseases), mela (skin diseases), stom (stomach diseases), test (testicular diseases), uter (uteππe diseases)
Utility preferred utilities for selected gene as descπbed in the text and abbreviated as follows CTL (DNA vaccme target), diag (diagnostic or prognostic target), mAb
(monoclonal antibody target), s m (small molecule target)
Pkey, ExAccn, UnigenelD, Unigene Title, Disease, Utility
100125, R02740, Hs 137555, putative chemokine receptor; G, blad, mAb+s m
100131, D12485, Hs 11951, ectonucleotide pyrophosphatase, breast, mAb
100147, D13666, Hs 136348, peπostin (OSF-2os), breast, colon, blad, lung, fibro, pane, mAb+diag
100241, BE273648, Hs 32963, cadhenn 6, type 2, K-cadhenn, blad, mAb
100299, D49493, Hs 2171, growth differentiation factor , EWS, diag
100335, AW247529, Hs 6793, platelet-activating factor ace, breast lung, blad, s m
100365, AI878927, Hs 79284, mesoderm specific transcπpt (, colon, pros, drag
100372, NM_014791, Hs 184339, KIAA0175 gene product, ovar, lung, cerv, pane, s m
100405, AW291587, Hs 82733, nidogeπ 2, angio, diag
100420, D86983, Hs 118893, Melanoma associated gene, breast, pros, lung, colon, angio, leuk, diag
100448, AF234887, Hs 57652, cadhenn, EGF UG seven-pass G, breast, mAb+s m
100452, D87742, Hs 241552, KIAA0268 protein, pros, diag
100559, NM_000094, Hs 1640, collagen, type VII, alpha 1 (e, lung, CTL+s m
100654, A03758, Hs 184411, N _000477* Homo sapiens albumi, pros, drag
100655, A03758, Hs 184411, Empiπcally selected from AFFX, pros, diag 100668, L05424, Hs 169610, CD44 antigen (homing function , lung, breast, mAb 100824, AI393237, Hs 193989, runt related transcnption fac, ovar; CTL+s m 100930, J04129, Hs 82269, progestagen-associated endomet lung, diag 101063, D54745, Hs 80247, cholecystokmin, pros, EWS, diag
101097, BE245301, Hs 89414, chemokine (C-X-C motif), recep leuk, ovar, breast, blad, mAb+s m 101104, AW862258, Hs 169266, neuropeptide Y receptor Y1, breast, EWS, mAb
101192, BE247295, Hs 78452, solute earner family 20 (phos, angio, mAb+s
101193, L20861, Hs 152213, wingless-type MMTV integration, blad, lung, drag 101249, L18964, Hs 1904, protein kinase C, iota, ovar, s m 101261, D30857, Hs 82353, protein C receptor, endothelia, angio, mAb+s m 101389, AW951430, Hs 78888, diazepam binding inhibitor (GA, pros, mAb+s m 101431, BE185289, Hs 1076, small proliπe-πoh protein 1B , lung, blad, drag 101447, M21305, , gb Human alpha satellite and s, angio, blad, drag 101461, N98569, Hs 76422, phospholipase A2, group IIA (p, pros, diag
101485, AA296520, Hs 89546, selectm E (endothelial adhesi, pros, ovar, mAb 101506, J02931, Hs 62192, coagulation factor III (thromb, pros, mAb 101526, NM_002197, Hs 220529, acomtase 1, soluble, lung colon, headnk, pane, mAb 101543, M31166, Hs 2050, peπtax related gene, rapidly, angio, ovar; diag 101545, BE246154, Hs 154210, endothelial differentiation, s, angio, mAb+s m
101560, AW958272, Hs 347326, intercellular adhesion molecul, angio, mAb 101626, M57399, Hs 44, pleiotrophin (hepaπn binding , lung, diag 101649, AW959908, Hs 1690, hepaππ binding growth factor , lung, blad, drag 101714, M68874 Hs 211587, phospholipase A2, group IVA (c, angio, s m 101724, L11690 Hs 198689 bullous pemphigoid antigen 1 (, breast, pros, blad, lung, mAb+CTL
101741, NMJ03199, Hs 326198, transcnption factor 4, angio, CTL+s m 101748, NMJ01944, Hs 1925 desmogleiπ 3 (pemphigus vulgar; lung, blad, headnk cerv, mAb 101759, M80244, Hs 184601, solute earner family 7 (catio, lung, glio, blad, headnk, mAb+s m 101791, M83822 Hs 62354, cell division cycle 4-lιke pros, s m 101804, M86699, Hs 169840, TTK protein kinase, ovar, lung, blad, cerv, CTL+s m
101806, AA586894, Hs 112408, S100 calcium binding protein A, lung, breast blad, diag
101809, M86849, Hs 323733, gap junction protein beta 2, , colon blad, lung, pane, headnk, mAb
101839, AA446644, Hs 692 GA733-2 antigen, epithelial gl, ovar, pros, mAb
101845, U88967, Hs 78867, protein tyrosine phosphatase, , lung, glio, headnk, cerv, mAb+s m 101851, BE260964, Hs 82045, midkine (neunte growth promot, lung, blad, ovar, breast pane, mAb+diag
102009, BE245149, Hs 82643, protein tyrosine kinase 9, ovar, s m
102012, BE259035, Hs 118400 singed (Drasophila) like (sea , angio, diag
102024, AA301867, Hs 76224, EGF-containing fibuliπ like ex, angio, diag
102048, U07225, Hs 339, puπnergic receptor P2Y, G-pro, blad, mAb 102076, BE299197, Hs 179665, cyclin-dependent kinase inhibi, pros, CTL+s m
102125, NM_006456, Hs 288215, sialyltransferase, breast, lung, ovar; s m
102136, AA300576 Hs 85769, acidic 82 kDa protein mRNA, ovaπ drag
102151, T27013, Hs 3132, steroidogenic acute regulatory, ovar, diag
102154, U17760, Hs 75517, laminm, beta 3 (nicein (125kD, lung, blad, headnk, drag 102178, AW178761, Hs 227948, seπne (or cysteine) protemas blad, mAb+diag
102187, U20325, Hs 1707, cocaine- and amphetamine regul, breast, diag
102193, AL036335, Hs 313, secreted phosphoprotein 1 (ost, ovar, lung, fibro, drag
102200, AA232362, Hs 317432, branched chain aminotransferas, ovar; s m
102208, U22961, Hs 184411, gb Human mRNA clone with simil, pros, drag 102211, BE314524, Hs 78776, putative transmembrane protein, breast, blad, mAb
102283, AW161552, Hs 83381, guanme nucleotide binding pro, angio, CTL+s m
102297, NMJ01504, Hs 198252, G protein-coupled receptor 9, breast mAb
102304, AF015224, Hs 46452, mammagtobin 1, breast, diag
102305, AL043202, Hs 90073, chromosome segregation 1 (yeas, ovar, lung, blad , diag 102348, U37519, Hs 87539, aldehyde dehydrogenase 3 famil, lung, blad, s m
102380, U40434, Hs 155981, mesothelin, ovar, diag
102394, NM_003816, Hs 2442, a disintegnn and metalloprote, pane, s m
102455, U48705, Hs 75562, discoidin domain receptor fami, breast, mAb
102457, NMJ01394, Hs 2359, dual specificity phosphatase 4, breast, s m 102522, BE250944, Hs 183556, solute carπerfamily 1 (neutn pros, mAb
102581, AU077228, Hs 77256, enhancer of zeste (Drasophila), blad, EWS, leuk, CTL+s m
102610, U65011, Hs 30743, preferentially expressed aπtig, lung, ovar, CTL
102623, AW249285, Hs 37110, melanoma antigen, family A, 9, lung, blad, mAb+CTL
102669, U71207, Hs 29279, eyes absent (Drasophila) homol, lung, pros, CTL+s m 102696, BE540274, Hs 239, forkhead box M1, lung, blad, s m
102725, AB026187, Hs 374280, pratocadheπn 11, EWS, mAb
102742, U79293, Hs 159264, Human clone 23948 mRNA sequeno, breast, ovar , diag
102745, AW753865, Hs 74376, olfactomedin related ER locali, EWS, drag
102803, H48299, Hs 26126, claudin 10, ovaπ mAb 102829, NM_006183, Hs 80962, neurotensin, lung, ovar, headnk, diag
102836, U94320, Hs 158330, neuropeptide Y receptor Y5, EWS, mAb
102852, V00571, Hs 75294, corticotropin releasing hormon, blad, diag
102898, NM_002205, Hs 149609, integπn, alpha 5 (fibronectin, angio, blad, lung, pros, mAb+s m
102915, X07820, Hs 2258, matnx metalloprateinase 10 (s, angio, blad, lung, ovaπ mAb+diag+s m 102917, AI016712, Hs 287797, integπn, beta 1 (fibronectin , angio, mAb
102927, BE512730, Hs 65114, keratin 18, ovar; diag
102968, AU076611, Hs 154672, methylene tetrahydrofolate deh, ovaπ s m
102994, X51730, Hs 2905, progesterone receptoπ blad, mAb+s m
103003, AI910275, Hs 350470, trefoil factor 1 (breast cance, breast pane, diag 103021, BE001596, Hs 85266, mtegπn, beta 4, lung blad, mAb
103036, M13509, Hs 83169, matrix metalloprotemase 1 (in, angio, colon, blad, lung, leuk, ovar, headnk, fibro, pane, stom, mAb+diag+s m
103037, BE018302, Hs 2894, placental growth factor, vascu, angio, drag
103060, NMJ305940, Hs 155324, matrix metalloprotemase 11 (s, breast, lung, ovar, pane, mAb+diag+s
103080, AU077231, Hs 82932, cycliπ D1 (PRAD1 parathyroid , breast, EWS, drag 103095, NM_005424, Hs 78824, tyrosine kinase with immunoglo, angio, mAb
103111, NM_006103, Hs 2719, epididymis-specific, whey-acid, ovar, uter, diag
103119, X63629, Hs 2877, cadhenn 3, type 1, P-cadheπn, lung, blad, ovar, colon, pros, pane, breast, mAb+diag
103206, X72755, Hs 77367, monokine induced by gamma inte, breast, lung, diag
103210, X72925, Hs 69752, desmocollm 1, pros, mAb 103280, U84722, Hs 76206, cadhenn 5, type 2, VE-cadheπ, angio, fibro, mAb+s m
103299, NM_005756, Hs 184942, G protein-coupled receptor 64, ovar, mAb+s m
103312, Y12642, Hs 3185, lysosomal, lung, blad, mAb
103365, X90908, Hs 74126, fatty acid binding protein 6, , blad, diag 103408 NMJ01504, Hs 198252, G protein-coupled receptor 9, breast , mAb
103478, BE514982, Hs 38991, S100 calcium-binding protein A, lung, blad, headnk, drag
103587, BE270266, Hs 82128, 5T4 oncofetal trophoblast glyc, breast, blad, lung, mAb
103594, AI368680, Hs 816, SRY (sex determining region Y), lung, glio, s m 103692, AW137912, Hs 227583, Homo sapiens chromosome X map , angio, mAb+s m
103739, AA115173, , gb zn30d02 s1 Stratagene neuro, pros, s m
103767, BE244667, Hs 348996, CGI-100 protein, angio, diag
103989, AA315993, Hs 105484, regenerating gene type IV, colon, omuc, mAb+diag
104052, NM_002407, Hs 97644, mammaglobin 2, ovar, diag 104115, AF183810, Hs 26102, opposite strand of tnchorhi, breast, mAb
104252, AF002246, Hs 210863, cell adhesion molecule with ho, ovar, diag
104301, AA768491, Hs 6783, hypothetical protein FU22724, ovaπ drag
104308, N25117, Hs 355957, πbosomal protein S26, pros, diag
104394, AA129551, Hs 172129, Homo sapiens cDNA FU21409 fi, colon, drag 104542, R29657, , gb F1-1179D 22 week old human , pros, diag
104608 AF143867, Hs 337588, ESTs, Moderately similar to S6, blad, mAb
104659, AW969769, Hs 100343, ESTs, EWS, diag
104660, BE298665, Hs 14846, Homo sapiens mRNA, cDNA DKFZp5, uter, colon, pros, mAb 104667, AI239923, Hs 63931, dachshund (Drasophila) homolog, breast pros, colon, diag 104689, AA420450, Hs 380088, Plakophilin, lung, drag
104691, U29690, Hs 37744, Homo sapiens beta-1 adrenergic, pros, EWS, mAb+s m 104755, T49951, Hs 9029, DKFZP434G032 protein, breast, colon, diag 104764, AI039243, Hs 278585, ESTs, angio, diag 104786, AA027167, Hs 380438 KIAA0955 protein, angio, CTL+s m 104877, AI138635, Hs 22968, intron of VEGFR, renal, drag
104888, AW939591, Hs 5940, mucin 13, epithelial transmemb, colon, stom, uteπ mAb+s m 104919, AA026880, Hs 25252, Homo sapiens cDNA FLJ13603 fis, breast, cerv, uter, mAb+s m 104943, AF072873, Hs 114218, fπzzled (Drasophila) homolog , ovaπ mAb+s m 104954, AW250651, Hs 26213, Human DNA sequence from clone , colon, drag 104971, BE311926, Hs 15830, hypothetical protein FLJ12691, blad, CTL
105012, AF098158, Hs 9329, chromosome 20 open reading fra, colon, lung, blad, CTL
105038, AW503733, Hs 9414, KIAA1488 protein, breast, angio, CTL+s m
105039, AA907305, Hs 36475, ESTs, breast, diag
105093, AL137566, Hs 32405, Homo sapiens mRNA, cDNA DKFZp5, blad, drag 105149, BE089288, Hs 8958, Homo sapiens cDNA FU12024 fis, pros, diag
105175, AA305384, Hs 25740, ER01 (S cerevisiae) like, colon, lung, mAb 105263, AW388633, Hs 6682, solute earner family 7, (cab, angio, lung, ovar, blad, pane, mAb+s m 105298, BE387790, Hs 26369, hypothetical protein FU20287, ovar, lung, drag 105301, AW352357, Hs 7457, MAGE1 protein, EWS, drag 105316, AI671245, Hs 24835, hypothetical protein FU14594, EWS, mAb
105329, AA234561, Hs 22862, ESTs, breast, pros, CTL+s m
105330, AW338625, Hs 22026, ESTs, similar toTRANSMEMBRAN, angio, mAb+s m 105370, AF179274, Hs 22791, transmembrane protein with EGF, pros , mAb+s m 105500, AW602166, Hs 222399, CEGP1 protein, breast, pros, drag 105503, AW963624, Hs 31707, ESTs, Weakly similar to YEW4_Y, pros, breast, colon, CTL+s m
105507, BE268348, Hs 380963, CCR4-NOT transcnption complex, colon, diag
105516, AK001269, Hs 30738, hypothetical protein FLJ10407, ovaπ diag
105564, BE616694, Hs 288042, hypothetical protein FLJ14299, breast, diag
105645, AW294631, Hs 351270, ESTs, pros, diag 105715, BE621800, Hs 29444, putative small membrane protei, colon, diag
105743, BE246502, Hs 9598, sema domain, immunoglobulin do, breast, lung, mAb+s m
105746, AW151952, Hs 46679, hypothetical protein FU20739, breast, CTL+s m
105777, R42755, Hs 23096, ESTs, breast, diag
105782, H09748, Hs 57987, B-cell CLL/lymphoma 11B (zinc , EWS, CTL+s m 105826, AA478756, Hs 194477, E3 ubiquitin ligase SMURF2, angio, s m
105990, AI690586, Hs 29403, hypothetical protein FU22060, breast, drag
106000; AW194426, Hs 20726, ESTs, breast, diag
106012, AI240665, Hs 352537, ESTs, breast, lung, diag
106014, AF123094, Hs 180566, mucosa associated ly phoid tis, leuk, diag 106063, BE260415, Hs 348198, hypothetical protein FU20262, pros, diag
106066, AW274357, Hs 301406, hypothetical protein PP3501, mela, CTL+s m
106111, AW875398, Hs 6451, PRO0659 protein, EWS, CTL+s
106124, H93366, Hs 7567, branched chain aminotransferas, angio, s m
106155, AA425414, Hs 33287, nuclear factor l/B, breast, pros, angio, diag 106373, AW503807, Hs 21907, histone acetyltransferase, breast, s
106400, BE397649, Hs 279607, Homo sapiens cDNA FU13634 fis, colon, diag
106414, BE568205, Hs 28827, itogen activated protein kiπa, breast s m
106448, Z42061, Hs 27004, ESTs, pros, diag
106533, AL134708, Hs 145998, ESTs, EWS, diag 106574, BE044325, Hs 227280, U6 snRNA-associated Sm-like pr, colon, drag
106579, AA456135, Hs 23023, ESTs, pros, diag
106632, NM 014400, Hs 11950, GPI-anchored metastasis-associ, lung, blad, headnk, mAb+diag
106738, AW149266, Hs 25130, Homo sapiens cDNA FU14923 fis, ovaπ drag
106793, H94997, Hs 16450, ESTs, angio, diag 106844, AA485055, Hs 158213, sperm associated antigen 6, breast mAb+CTL
106906, AA861271, Hs 222024, transcnption factor BMAL2, lung blad, drag
106990, AA280722, Hs 24758, ESTs, Weakly similar to 138022, breast, drag
107036, A1973016, Hs 15725, hypothetical protein SBBI48, pros, diag
107102, AB037765, Hs 30652, KIAA1344 protein, pros, breast, drag 107105, AW963419, Hs 155223, stanπiocalcin 2, breast, diag
107136, AV661958 Hs 8207, GK001 protein, breast, colon, diag
107151, AW378065, Hs 8687, ADAMTS2 (a disintegπn-like a, breast, colon, leuk, lung, blad, mAb+diag
107216, D51069, Hs 211579, melanoma cell adhesion molecul, angio, diag 107248, AW263124, Hs 350547, nuclear receptor co-repressor/, breast, colon, pros, mAb+s m 107284, NM_005629, Hs 187958, solute earner family 6 (neuro, lung, mAb+s m 107385, NM_005397, Hs 16426, podocalyxin like, angio, diag 107901, L42612, Hs 335952, keratin 6B, breast, blad, lung, diag 5 107922, BE153855, Hs 61460, Ig superfamily receptor LNIR, breast blad, lung, mAb
107932, AW392555, Hs 18878, hypothetical protein FLJ21620, lung, CTL 108055, AJ404672, Hs 334483, hypothetical protein FLJ23571, breast, ovaπ diag 108059, S69002, Hs 234773, Homo sapiens cDNA FLJ22281 fi, ovaπ CTL+s m 108153 AW519204, Hs 40808, ESTs, pros, drag 0 108186, AW068579 Hs 7780 Homo sapiens mRNA cDNA DKFZpδ pros. diag
108242, AA062746, Hs 355244, gb zm03g12 s1 Stratageπe corπe, pros, drag 108282, AA065142, , gb zm50h11 r1 Stratageπe fibro, pros drag 108505, AA083376, , gb zn09g08 s1 Stratagene hNT n, pros, drag 108679, AA115963 Hs 323423 ESTs, Moderately similar to B , pros, drag 5 108695 AB029000 Hs 70823, KIAA1077 protein, breast colon lung, diag
108732, AA258888, Hs 107476, ATP syπthase, H+ transporting,, pros, s m 108778 AF133123, Hs 90847, general transcnption factor I, ovar, drag 108828, AK001693, Hs 273344, DKFZP564O0463 protein, breast, drag 108860, AA133334, Hs 816, ESTs, lung, s m 0 109001, AI056548, Hs 72116, hypothetical protein FLJ20992 , angio, CTL+diag
109032, AI219207, Hs 72222, hypothetical protein FU13459, blad, CTL 109077, AI732617, Hs 182362, ESTs, blad drag
109112, AW419196, Hs 257924, hypothetical protein FLJ13782, breast, pros, blad, diag 109141, AF174600, Hs 5978, ESTs, Highly similar to AF1746, colon, CTL+s m 5 109166, AA219691, Hs 73625, RAB6 interacting, kinesiπ like, lung, blad, breast, colon, ovar, headnk, EWS, s m
109220, AW958181, Hs 189998, ESTs, pros, drag
109273, AA375752, Hs 348140, Homo sapiens mRNA cDNA DKFZpδ, breast, diag 109292, AW975746, Hs 188662, KIAA1702 protein, breast, diag 109454, AA232255, Hs 295232, ESTs, Moderately similar to A4, ovar, diag 0 109456, AW956580, Hs 42699, ESTs, angio, pane, drag
109514, AA234087, Hs 262346, ESTs, Weakly similar to S72482, breast , drag 109530, AA908645 Hs 19597, KIAA1694 protein, pros, CTL+s m 109648, H17800, Hs 7154, ESTs, ovaπ drag 109680, AB037734, Hs 4993, KIAA1313 protein, ovar, diag 5 110009, BE075297, Hs 6614, ESTs, Weakly similar to A43932, breast, colon, drag
110151, H18835, Hs 31608, hypothetical protein FLJ20041, pros, EWS, diag 110156, AA581322, Hs 4213, hypothetical protein MGC16207, lung, blad, diag 110240, AI668594, Hs 176588, ESTs, Weakly similar to CP4Y_H, breast, diag 110278, AF061573 Hs 19492, protooadheπn 8, EWS, mAb+s m 0 110675, H89355, Hs 249159, adrenergic, alpha 2A-, recepto, pros, mAb+s m 110728, AA737106, Hs 32250, ESTs, Moderately similar to 17, EWS, s m 110844, AI740792, Hs 167531, methylcrotonoyl-Coenzyme A can pros, pros s m 110915, BE092285, Hs 29724, hypothetical protein FLJ13187, breast, pros, diag 110971 , AI760098 Hs 21411 , ESTs, pros, drag 5 111157, AL109729, Hs 99364, putative transmembrane protein, pros, mAb+s m
111179, AK000136, Hs 10760, aspoπn (LRR class 1), breast, colon, CTL+s m 111185, AJ245671, Hs 12844, EGF-like-domam, multiple 6, ovar, blad, mAb+diag 111223, AA852773, Hs 334838, KIAA1866 protein, breast, colon, lung, EWS, mAb 111299, AB033091, Hs 355925, KIAA1265 protein, ovaπ diag 0 111357, BE314949, Hs 87128, hypothetical protein FU23309, breast, drag
111384, N94606, Hs 288969, HSCARG protein, breast, diag 111900, AF131784, Hs 25318, Homo sapiens clone 25194 mRNA , breast, diag 111929, AF027208, Hs 112360, promimn (mouse)-lιke 1, colon, breast, fibro, mAb _ _ 112134, 41823, Hs 7413, ESTs, calsyπtenιn-2, breast, EWS, diag 5 112244, AB029000, Hs 70823, KIAA1077 protein, breast colon, blad, lung, diag
112280, AA863360, Hs 26040, ESTs, Weakly similar to fatty , breast, s 112283, L14561, Hs 20952, ATPase, Ca++ transporting, pla, ovar, mAb 112287, AB033064, Hs 236463, KIAA1238 protein, breast , drag 112971, Z42387, Hs 83883, transmembrane, prostate androg, colon, pros, pros, mAb+s m 60 113003, AW292315, Hs 7215, ESTs, EWS, diag
113021, AL122055, Hs 129836, KIAA1028 protein, pros, s m 113047, AI571940, Hs 7549, ESTs, breast, colon, drag 113073, N39342, Hs 103042, microtubule-associated protein, pros, CTL+s m 113168, AW002393, Hs 337629, gb wu61d05 x1 NCI_CGAP_GC6 Hom, ovar, diag 65 113195, H83265, Hs 8881, ESTs, Weakly similar to S41044, angio, lung, diag
113230, T61430, , gb yc06a03 s1 Stratagene lung , blad, diag
113361, T79589, Hs 63325, transmembrane protease, senne, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m 113374, T79925, Hs 269165, ESTs, Weakly similar to ALU1_H, leuk, diag 113443, AW083920, Hs 16098, claudin 2, colon, pane, mAb 70 113471, AI765890, Hs 16341, MAWD binding protein, pros, diag
113490, BE178110, Hs 173374, Homo sapiens cDNA FU10500 fis, colon, diag 113950, AI267652, Hs 246107, Homo sapiens mRNA, cDNA DKFZp4, breast, pros , diag 113970, W27249, Hs 8109, hypothetical protein FLJ21080, breast lung, stom, uteπ drag 114124, W57554, Hs 125019, lymphoid nuclear protein (LAF-, breast, diag 75 114251, H15261, Hs 21948, ESTs, breast, diag
114292, AI815395, Hs 184641, fatty acid desaturase 2, breast, s m 114334, AB037784, Hs 22941, KIAA1363 protein, ovar, diag
114407, BE539976, Hs 103305, Homo sapiens mRNA, cDNA DKFZp4, breast, colon, lung, diag 114452, AI369275, Hs 243010, Homo sapiens cDNA FLJ14445 fis, angio, diag 80 114480, BE066778, Hs 151678, UDP-N-acetyl-alpha-D galactosa, breast s
114531, AA053033, Hs 63325, transmembrane protease, seπne, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m
114540, AI904232, Hs 75323, prohibitin, breast, drag
114542, AW970128, Hs 91011 , anteπor gradient 2 (Xenepus I, breast pros, drag 114587, AF086009, Hs 296398, gb Homo sapiens full length in, colon, drag 114724, R64730 comp, Hs 155986, DEAD/H (Asp-Glu Ala-Asp/His) b, ovar, CTL+s m 114768, AF212848, Hs 182339, ets homologous factoπ pros, breast, colon, CTL+s 114798, AA159181, Hs 54900, serologioally defined colon ca, pros, CTL+s m 114908, AA454985, Hs 54973, cadhenn like protein VR20, pros, drag
114918, BE165762 Hs 23518, hypothetical protein from BCRA, pros, drag 114965, AI733881 , Hs 72472, NAME OMITTED receptor kinase, breast, mAb 115060, AF052693 Hs 198249, gap junction protein, beta 5 (, lung, blad, headnk, mAb+s m 115221, AW365434, Hs 79741, hypothetical protein FU10116, ovaπ drag 115239, BE251328, Hs 73291, hypothetical protein FLJ10881, colon, drag
115291, BE545072, Hs 122579, hypothetical protein FLJ10461, ovar, lung, CTL+s m 115412, AW131168, Hs 372382, ESTs, Weakly similar to 138022, pros, drag
115536, AK001468, Hs 62180, anillin (Drasophila Scraps hom, ovar, lung, blad, headnk, pane, cerv, stom, uter, colon, CTL+s m 115674, AW992356 Hs 380760, Homo sapiens pyruvate dehydrog, ovaπ s m 115675, W87707, Hs 82065, interleukin 6 signal transduce, breast, pros mAb+s m
115683 AF255910, Hs 54650, juπctional adhesion molecule 2, angio, glio, mAb
115697, D31382, Hs 63325, transmembrane protease, senne, colon, blad, lung, ovar, pane, headnk mAb+diag+s m 115719, AW992405, Hs 352406, Homo sapiens, clone IMAGE 3507, pros, breast colon CTL+s m 115819, AA486620, Hs 41135, endomucιn-2, angio, diag 115827, AA428000, Hs 283072, actin related protein 2/3 comp, angio, drag
115844, AI373062, Hs 332938, hypothetical protein MGC5370, pros, diag 115881, NM_005756, Hs 184942, G protein-coupled receptor 64, ovar, EWS, uteπ mAb+s m 115892, AA291377, Hs 50831, ESTs, ovar, blad, lung, drag 115909, AW872527, Hs 59761 , ESTs, Weakly similar to DAP1_H, ovar, lung, drag 115947, R47479, Hs 94761, KIAA1691 protein, colon, diag
115978, AL035864, Hs 69517, cDNA for differentially expres, lung, blad, breast, pros, ovar, headnk, CTL 116003, BE275469, Hs 66493, Down syndrome cntioal region , colon, mAb 116011, AL359053, Hs 57664, Homo sapiens mRNA full length , breast diag 116028, H59799 Hs 42644, thioredoxm like, ovar, lung, drag 116107, AL133916, Hs 47860, hypothetical protein FU20093, lung breast drag
116202, BE159395 Hs 294092, ESTs, pros, drag 116238, AV660717, Hs 47144, DKFZP586N0819 protein, ovar, drag 116301, AW969706, Hs 293332, ESTs, EWS, drag 116334, AL038450, Hs 48948, ESTs, pros, drag 116335, AK001100, Hs 41690, desmocollin 3, lung, blad, headnk, diag
116393, AI972402, Hs 306051, hypothetical protein MGC2648, pros, diag 116399, AA889120, Hs 110637, homeo box A10, pros, CTL+s m 116401, AW893940, Hs 59698, ESTs, ovar, diag 116416, AW753676, Hs 39982, ESTs, ovaπ diag 116470, AI272141, Hs 351928, SRY (sex determining region Y), colon, breast, angio, blad, drag 116483 AI346201, Hs 76118, ubiquitin carboxyl-termiπal es, angio, lung, s m
116610, D80449, Hs 184841, ESTs, pros, diag
116732, AW152225 Hs 165909, ESTs, Weakly similar to I38022, colon, drag
116787, AW362955, Hs 356547, Homo sapiens cDNA FLJ14415 fis, pros, breast, colon, pros, mAb 116962 H79677, , gb yu76g10 s1 Soares fetal liv, pros, diag
117027, AW085208, Hs 130093, ESTs, breast , drag
117280, M18217, Hs 172129, Homo sapiens cDNA FU21409fi, breast colon, pros, drag
117284, AK001701, Hs 183779, Homo sapiens cDNA FU10590 fis, pros, diag
117320, AB024937, Hs 211092, LUNX protein, PLUNC (palate lu, lung, mAb+diag 117367, AI041793, Hs42502, ESTs, breast, diag
117412, N32536, Hs 42645, solute earner family 16 (mono, breast ovar , mAb+s m
117425, AK000028, Hs 356100, nbosomal protein S24, pros, diag
117563, AF055634, Hs 44553, unc5 (C elegans homolog) c, leuk , drag
117602, N35020, Hs 44685, C3HC4-lιke zinc finger protein, EWS, CTL+s m 117921, AA021459, Hs 306480, Homo sapiens mRNA, cDNA DKFZp7, pros , drag
117984, AF189723, Hs 106778, ATPase, Ca++ transporting, typ, pros, breast, colon, mAb
118049, N53145, , gb yv55f09 s1 Soares fetal liv, pros, drag
118314, N48580, Hs 46692, ESTs, blad, lung, diag
118336, BE327311, Hs 47166, HT021, breast, ovar, blad, pros, CTL+s m 118368, N64339, Hs 48956, gap junction protein, beta 6 (, lung, blad, mAb
118417, AF080229, , gb Human endogenous retrovirus, pros, s
118472, AL157545, Hs 173179, bromodomain and PHD finger con, breast, diag
118511, N75620, Hs 43157, ESTs, angio, diag
118901, AW292577, Hs 94445, ESTs, breast, diag 118905, AW973708, Hs 201925, Homo sapiens cDNA FU13446 fis, breast, drag
119018, AA631143, Hs 278695, Homo sapiens prostein mRNA, co, pros, pros, drag
119036, R95872, Hs 117572, chemokine binding protein 2, breast, ovar, mAb
119073, BE245360, Hs 45514, v-ets erythroblastosis virus E, angio, pros, CTL+s m
119082, AF252297, Hs 91546, cytochrome P450 retiπoid metab, EWS, diag 119126, R45175, Hs 117183, ESTs, pros, breast colon, diag
119279, N57568, Hs 48028, EST, breast, diag
119307, BE048061, Hs 37054, ephππ-A3, colon, breast, mAb+diag
119478, AI624342, Hs 179082, ESTs, breast, diag
119617, AA516531, Hs 55999, NK homeobox (Drasophila), fami, pros, diag 119743, AA947552, Hs 58086, branched chain ammotransferas, ovaπ s
119771, AI905687, Hs 348419, AI905687 IL BT095-190199-019 B, breast drag
119780, NM_016625, Hs 191381, hypothetical protein, ovar, lung CTL+s m
119789, BE393948, Hs 50915, kallikrein 5, ovar, drag
119845, W79123, Hs 58561, G protein-coupled receptor 87, lung, blad, headnk, cerv, mAb+s m 119940, AL050097, Hs 272531, DKFZP586B0319 protein, pros, diag
120104, AK000123, Hs 180479, hypothetical protein FU20116, colon, lung drag
120132, W57554, Hs 125019, lymphoid nuclear protein (LAF-, pros, breast drag
120147, AI917116 Hs 348941, hemoglobin, beta, EWS, diag 120206, H26735, Hs 91668, Homo sapiens clone PP1498 unkn, breast , mAb
120242, AW969587, Hs 86366, ESTs, blad, diag
120328, AA923278, Hs 290905, ESTs, Weakly similar to protea, pros, s m
120438, AW015242, Hs 99488, ESTs, Weakly similar to YK54_Y, ovaπ diag 120471, AA251944, Hs 104058, CGI-29 protein, colon, drag
120486, AW368377, Hs 137569, tumor protein 63 kDa with stro, lung, blad, headnk, diag
120588, AA703226, Hs 16193, Homo sapiens mRNA, cDNA DKFZpδ, pros, drag
120624, AW407987, Hs 173518, M phase phosphoprotein homolog, breast, s m
120830, AI568170, Hs 96886, ESTs EWS, drag 120977, AA398155, Hs 97600, ESTs, breast, ovar, diag
121027, AI572490, Hs 99785, Homo sapiens cDNA FLJ21245 „, blad, mAb
121231, AA814948, Hs 96343, ESTs, Weakly similar to ALUC_H, EWS, diag
121335, AA404418, , gb zw37e02 s1 Soaresjotal et, angio, drag
121362, AF050147, Hs 97932, chondromodulin I precursor, EWS, mAb 121457, W07404, Hs 102558, hypothetical protein FLJ22055, colon, drag
121619, AA528339, Hs 178062, ESTs, Weakly similar to phosph, EWS, s m
121710, AF163474, Hs 96744, prostate androgeπ-regulated tr, pros, diag
121721, AL047051, Hs 199961, ESTs, Weakly similar to ALU7_H, pros, drag
121723, AA243499, Hs 104800, hypothetical protein FLJ10134, breast, drag 121748, BE536911, Hs 234545, hypothetical protein NUF2R, breast, drag
121779, AW513143, Hs 98367, SRY (sex determining region Y), ovar, diag
121791, AA815378, Hs 293317, ESTs, Weakly similar to GGC1 H, blad, headnk, lung, ovaπ mAb+CTL
121792, AW969726, Hs 98381 , ESTs, Weakly similar to serine, EWS, drag 121913, AI249368, Hs 98558, ESTs, protease inhibitor 15 (, breast, pros, s m 121920, AA428300, , gb zw18b02 s1 Soares ovary turn, ovar, uter, cerv, drag
122041, AA677577, Hs 380213, Homo sapiens Chromosome 16 BAC, pros, diag 122520, AW951324, Hs 173609, pregnancy specific beta-1-glyc, colon, diag 122797, AJ251027, Hs 99526, odorant binding protein 2B (OB, breast, drag 122802, AI687303, Hs 285529, G protein-coupled receptor 49, ovar, uter, mAb+s m 122969, AW821252, Hs 104336, hypothetical protein, ovar, diag
123005, AW369771, Hs 367688, integπn, beta 8, ovar, lung, headnk glio, mAb+s m 123044, AK001035, Hs 130881, B-cell CLL/lymphoma 11A (zinc , lung, diag 123137, AI073913, Hs 100686, ESTs, Weakly similar to JE0350, breast, colon, ovar, uter, lung, stom, drag 123158, AF161426, Hs 218329, hypothetical protein, breast, diag 123160, AA488687, Hs 284235, ESTs, Weakly similar to I38022, lung, diag
123169, AI950087, Hs 369628, gb wq05c02x1 NCI CGAP Kιd12 H, ovar, diag 123209, AW968543, Hs 203270, ESTs, Weakly similar to ALU1_H, pros, drag 123308, C14187, Hs 157208, ESTs, EWS, drag 123339, AW188464, Hs 101515, ESTs, ovaπ drag 123475, BE439553, Hs 12329, Homo sapiens, clone IMAGE 4098, pros, diag
123494, AW179019, Hs 112110, mitochondπal πbosomal protei, ovaπ drag 123520, AA608550, , gb ae53d12 s1 Stratagene lung , pros, s m 123533, AA608751, , gb ae56h07 s1 Stratagene lung , colon, diag 123619, AA602964, Hs 366318, gb no97c02 s1 NCI_CGAP_Pr2 Hom, breast, CTL+s m 123689, AA399323, Hs 285130, Homo sapiens pιnch-2 protein m, ovar, drag
123709, AA706910, Hs 112742, ESTs, breast diag 123829, AF251237, Hs 112208, XAGE-1 protein, lung, blad, test, CTL 123972, T46848, Hs 70337, immunoglobulin superfamily, me, ovaπ drag
124006, AI147155, Hs 279727, ESTs, homologue of PEM-3 [Cion, breast, angio, lung, ovar, EWS, drag 124059, BE387335, Hs 283713, ESTs, Weakly similar to S64054, breast, colon, blad, lung, CTL+diag
124153, AU077333, Hs 160483, erythrocyte membrane protein b, pros, mAb 124352, AA640891, Hs 102406, ESTs, breast, pros, ovar, lung, drag 124526, N62096, Hs 293185, ESTs, Weakly similar to JC7328, pros, mAb+s m 124579, AI693815, Hs 127179, cryptic gene, pane, diag 124777, R41933, Hs 140237, ESTs, Weakly similar to ALU1_H, pros, breast, diag
125103, AA570056, Hs 122730, ESTs, Moderately similar to Kl, colon, mAb 125154, W38419, , gb zc78a07 s1 Pancreatic Islet, ovar, diag 125250, W26524, Hs 356686, protein phosphatase 4 regulato, ovaπ CTL+s m 125266, W90022, Hs 186809, ESTs, Highly similarto LCT2_H, angio, drag 125453, BE385523, Hs 18048, melanoma antigen, family A, 10, blad, mAb+CTL
125666, AL390172, Hs 317432, Homo sapiens cDNA FLJ21270 ti, ovaπ diag 125770, AA143045, Hs 81665, v-kit Hardy-Zuckerman 4 feline, EWS, drag 125976, AA436760, Hs 35552, gb zv67d11 r1 Soares_total_fet, pros, diag 126399, AA088767, Hs 83883, transmembrane, prostate androg, pane, mAb+s m 126645, AA316181, Hs 61635, six transmembrane epithelial a, pros, breast, lung, pane, headnk, EWS, mAb+CTL
126758, AI559444, Hs 104679, ESTs, pros, breast, mAb 126799, AW753865, Hs 74376, olfactomedm related ERIooali, EWS, drag 126872, AW450979, , gb UI-H-BI3-ala-a-12-0-UI s1 N, blad, diag 126892, AF121856, Hs 284291, sorting πexin 6, ovar, diag 126960, AL390172, Hs 317432, branched chain aminotransferas, ovaπ s m 126966, R38438, Hs 118747, solute earner family 15 (H+/p, pros, mAb 127003, AW816515, Hs 173540, ATPase, Class V, type 10D, pros, mAb 127221, BE062109, Hs 241551, chloπde channel, calcium acti, lung, blad, headnk, cerv, mAb+s m 127240, AJ005683, Hs 86998, nuclear factor of activated T-, pros, CTL+s m 127425, AF183810, Hs 26102, tπchorhinophalangeal syndrome, breast, mAb
127479, D31152, Hs 179729, collagen, type X, alpha 1 (Sch, breast, lung, headnk, pane, diag 127537, AI926047, Hs 162859, ESTs, pros, diag 127664, AA806164, Hs 116502, ESTs, EWS, diag
128046, AA873285, Hs 357313, gb Oh68h05 s1 NCI_CGAP_Kιd5 Ho, pros, breast, colon, drag 128305, AI954968, Hs 365706, matrix Gla protein, breast drag
128478, AA708205, Hs 100343, ESTs, EWS, CTL+s 128515, BE395085, Hs 334762, type I transmembrane protein F, pane, mAb 128595, U31875, Hs 272499, short-chain alcohol dehydrogen, blad, breast, CTL+s m 128610 N48373, Hs 10247, activated leucocyte cell adhes, breast, pros, lung, ovar, drag 128734, AB008390, Hs 104570, kallikrein 8 (neuropsin/ovasin, ovar, diag
128790, AF026692, Hs 105700, secreted fnzzled-related prot breast colon, pros, ovar, uter, pane, diag 128797, NM 002975, Hs 105927, stem cell growth factor, lymph, EWS, leuk, drag 128854, BE159181, Hs 168232, hypothetical protein FLJ13855, breast, diag
128925, R67419, Hs 21851, Homo sapiens cDNA FU12900fis, breast, drag
128949, AA009647, Hs 352537, a disintegnn and metaltoprote, breast, ovar, headnk, pane, mAb+diag+s m 128969, Z42047, Hs 107479, Homo sapiens PR02751 mRNA, com, pros, diag 129041, BE382756, Hs 169902, solute earner family 2 (facil, lung, blad, mAb+s m 129097, BE243933, Hs 108642, zinc finger protein 22 (KOX 15, ovaπ CTL+s m
129099, AF146074, Hs 108660, ATP-binding cassette, sub farm, lung blad, headnk , mAb+s m 129184, AW161450, Hs 109201, CGI-86 protein, pros, mAb 129260, AF077200, Hs 279813, hypothetical protein, colon, diag 129284, AA318224, Hs 296141, ESTs, colon, diag 129362, U30246, Hs 110736, solute earner family 12 (sodi, colon, breast, pros, mAb 129366, BE220806, Hs 184697, Homo sapiens clone 23785 mRNA , breast drag 129389, NM_012445, Hs 288126, spondin 2, extrxellular matπ, colon, pros, drag 129404, AI267700, Hs 351201, ESTs, pros, ovar, lung, blad, headnk, pane, drag 129466, L42583, Hs 334309, keratin 6A, lung, blad, drag 129482, AA188185, Hs 289043, spmdlin, breast, drag
129534, AK002126, Hs 11260, hypothetical protein FLJ11264, pros, drag 129571, X51630, Hs 1145, Wilms tumor 1, ovaπ CTL+s m
129605, AF061812, Hs 115947, keratin 16 (focal πon-epidermo, lung, blad, headnk, drag 129620, D79338, Hs 239720, CCR4-NOT transcnption complex, breast, angio, drag 129628, U38945, Hs 1174, cyclin-dependent kinase inhibi, lung, blad, ovar, headnk, s m 129650, AF109298, Hs 118258, prostate cancer associated pro, pros, EWS, drag 129689, AW748482, Hs 77873, B7 homolog 3, breast, drag 129703, BE388665, Hs 179999, Homo sapiens, clone IMAGE 3457, EWS, leuk, drag 129720, AA156214, Hs 12152, APMCF1 protein, breast drag 129750, AF056085, Hs 198612, G protein-coupled receptor 51, angio, blad, mAb+s m
129869, AI222069, Hs 13015, hypothetical protein similart, breast, drag 129912, AF155096 Hs 107213, hypothetical protein FLJ20585, ovaπ CTL+s m 129936, AJ250717, Hs 1355, cathepsin E, blad, sm+diag 129953, AA412195, Hs 13740, ESTs, breast, drag 129977, NMJ00399, Hs 1395, early growth response 2 (Krox-, EWS, CTL+s m
130010, AA301116, Hs 142838, nuoleolar phosphoprotein Nopp3, ovaπ diag 130057, AF027153, Hs 324787, solute earner family 5 (inosi, breast, mAb 130095, AK001635, Hs 14838, hypothetical protein FU10773, breast, drag 130155, AA101043, Hs 151254, kallikrein 7 (chymotryptic, st, ovaπ drag 130181, AF052119, Hs 151608, Homo sapiens clone 23622 mRNA , pros, drag
130184, H58306, Hs 15165, retinoic acid induced 14, angio, drag 130262, D63216, Hs 153684, frizzled related protein, pane, EWS, stom, renal, drag 130343, AB040914, Hs 278628, KIAA1481 protein, breast, diag 130376, R40873, Hs 155174, CDC5 (cell division cycle 5, S, ovaπ CTL+s 130385, AW067800, Hs 155223, stanniocalcin 2, breast, lung, mAb+diag 130455, D90041, Hs 155956, N acetyltransferase 1 (arylami, breast, s m 130511, L32137, Hs 1584, cartilage oligomeπc matnx pπ breast, ovar, diag 130558, BE564937, Hs 15984, pp21 homolog, pros, CTL+s m 130577, M69241, Hs 162, insulin-like growth factor bin, ovaπ drag 130604, AA383256, Hs 1657, estrogen receptor 1, breast, mAb+s m
130627, BE003054, Hs 1695, matnx metaltoproteinase 12 (m, lung, colon, blad, headnk, ovar, pane, mAb+diag+s m 130637, AA356764, Hs 17109, integral membrane protein 2A, EWS, mAb+s m 130648, AI458165, Hs 17296, hypothetical protein MGC2376, colon, diag 130667, BE246961, Hs 17639, Homo sapiens ubiquitin protein, breast, s m 130690, AB006625, Hs 139033, paternally expressed 3, ovaπ diag
130714, AI348274, Hs 18212, DNA segment on chromosome X (u, breast, diag 130760, AW379130, Hs 18953, phosphodiesterase 9A, pros, CTL+s m 130800, AI187292, Hs 19574, hypothetical protein MGC5469, colon, lung, diag 130839, AB011169, Hs 380875, similar to S cerevisiae SSM4, angio, diag 130844, U76248, Hs 20191, seven in absentia (Drasophila), breast, diag
130892, AL120837, Hs 20993, high-glucose-regulated protein, breast, CTL+s m 130941, NM_000869, Hs 2142, 5-hydroxytryptamιne (serotonin, ovaπ mAb 130967, AA393071, Hs 182579, leucine aminopeptidase, ovar, s 130972, D81866, Hs 374468, Homo sapiens mRNA, cDNA DKFZp5, angio, drag 130987, BE613269, Hs 21893, hypothetical protein DKFZp761N, colon, drag
131046, AA321649, Hs 2248, small inducible cytokine subfa, breast, lung, blad, ovar, fibro, diag 131080, NM_001955, Hs 2271, endothelin 1, angio, drag 131083, Y09763, Hs 22785, gamma-aminobutyπc acid (GABA), pros, mAb 131148, AW953575, Hs 303125, p53-ιnduced protein PIGPC1, breast, colon, angio, drag 131216, AI815486, Hs 243901, Homo sapiens cDNA FU20738 fis, colon, breast, drag 131228, AW207469, Hs 24485, chondroitiπ sulfate proteogiyc, ovaπ diag 131244, AI638429, Hs 24763, RAN binding protein 1, lung, blad, headnk, CTL+s m
131288, AA278482, Hs 25328, ESTs, Moderately similar to AL, pros, drag
131289, AA296696, Hs 333418, FXYD domain containing ion tra, colon, diag 131307, NM_000025, Hs 2549, adrenergic, beta-3-, receptoπ EWS, mAb
131313, R96290, Hs 75874, πbosomal protein L44, EWS, drag 131492, AI452601 , Hs 288869, nuclear receptor subfamily 2, , pros, mAb+s m 131544, AL355715, Hs 28555, programmed cell death 9 (PDCD9, breast, drag 131559, AL078599, Hs 10784, hypothetical protein FLJ20037, breast, diag 131564, T93500, Hs 28792, Homo sapiens cDNA FU11041 As, breast, drag
131603 X81334, Hs 2936, matnx metalloprotemase 13 (c, blad, s m 131643, AW410601, Hs 30026, HSPC182 protein, breast, drag 131739, AF017986, Hs 31386, secreted frizzled related prot breast, mAb+s m 131817, U20536, Hs 3280, caspase 6, apoptosis-related c, fibro, breast, cerv, lung, blad, pane, glio, s m 131885, BE502341, Hs 3402, ESTs, breast, drag 131919, T15803, Hs 272458, protein phosphatase 3 (formed, pros, breast, s m 131925, AF151048 Hs 183180, anaphase promoting complex sub, breast, diag 131965, W79283, Hs 35962, ESTs, lung, ovaπ diag
131985, AA503020, Hs 36563, hypothetical protein FU22418, breast, ovaπ diag 132050, AI267615 Hs 38022, ESTs, angio, diag 132173, X89426, Hs 41716, endothelial cell specific mole, angio, drag 132180, NM 004460, Hs 418, fibroblast activation protein,, colon, pane, esoph, mAb 132191, AA507576, Hs 288361, Homo sapiens cDNA FLJ22696 fi, ovar, diag
132349, AW975654, Hs 181286, seπne protease inhibitor, Kaz, pros, blad s m 132354, BE185289, Hs 1076, small proline πch protein 1B , lung, diag 132358, NM 003542, Hs 46423, H4 histone family, member G, pros, CTL+s m 132371, AA235448, Hs 222088, PRO2000 protein, breast, diag 132454, BE296227, Hs 250822, seππe/threonme kinase 15, blad, breast s m
132490, NM_001290, Hs 4980, UM domain binding 2, angio, drag 132520, AA257992, Hs 50651, Janus kinase 1 (a protein tyro, EWS, s m 132528, T78736, Hs 50758, SMC4 (structural maintenance o, ovaπ CTL+s m 132543, BE568452, Hs 344037, protein regulator of cytokines, colon, lung, drag 0 132572, AI929659, Hs 237825, signal recognition particle 72, ovar, diag
132592, AW803564, Hs 288850, Homo sapiens cDNA FLJ22528 fi, colon, drag 132624, AA326108 Hs 33829, bHLH protein DEC2, ovar, drag 132632, AU076916, Hs 5398, guanine monphosphate synthetas, ovar, lung, s m 132669, W38586, Hs 380933, guanine nucleotide binding pro, colon, diag 5 132710, W74001, Hs 55279, seπne (or cysteine) proteinas, lung, blad, colon, headnk, diag
132725, NMJ06276, Hs 184167, splicing factor, arginine/seπ, ovaπ CTL+s m 132767, BE182592, Hs 11261, small proline-πch protein 2A, lung, drag 132791, AB029551, Hs 7910, RING1 and YY1 binding protein, pros, CTL+s m 132837, AA370362, Hs 57958, EGF-TM7-latrophιlιn related pπ angio, drag O 132856 NM_001448, Hs 58367, glypican 4, breast, colon, pros, mAb
132888, NMJ05476, Hs 5920 UDP-N-acetylglucosamιne-2-epιm, pros, s m 132902, AI936442, Hs 59838, hypothetical protein FLJ10808, colon, drag 132939, AB009284, Hs 61152, exostoses (multιple)-lιke 2, ovaπ drag 132964, AI362575, Hs 303171, ESTs, pros, diag 5 132967, AA316181, Hs 61635, six transmembrane epithelial a, pros, pros, mAb+CTL
132990, X77343, Hs 334334, transcnption factor AP-2 alph, breast, lung, CTL+s m 132994, AA112748, Hs 279905, clone HQ0310 PRO0310p1, colon, breast, s 133006, AW978436, Hs 62515, KIAA0494 gene product, colon, drag 133015, AJ002744, Hs 246315, UDP-N-acetyl-alpha-D-galactosa, breast, colon, pros, s m 0 133016, AI439688, Hs 6289, hypothetical protein FU20886, breast, diag
133061, AI186431, Hs 296638, prostate differentiation facto, angio, pros, blad, diag 133063, AI654133, Hs 356247, thyroid receptor interacting p, pros, mAb+s m 133070, U92649, Hs 380136, a disintegnn and metaltoprote, leuk, drag 133179, U81599, Hs 66731, homeo box B13, pros, CTL+s m 5 133199, AF231981, Hs 250175, homolog of yeast long chain po, breast, angio, CTL+s m
133260, AA403045, Hs 6906, Homo sapiens cDNA FU23197 fi, angio, drag 133272, NM_002776, Hs 69423, kallikrein 10, colon, ovar, diag 133314, AA102670, Hs 70725, gamma-amiπobutyπc acid (GABA), breast pane, mAb 133321, T79526, Hs 179516, integral type I protein, breast, diag 0 133391, AW103364, Hs 727, inhibin, beta A (activin A, ac, breast, blad, lung, diag 133415, X69699, Hs 73149, paired box gene 8, ovar, CTL 133477, AW502935, Hs 740, PTK2 protein tyrosine kinase 2, breast s m 133579, X75346, Hs 75074, mitogen-activated protein kina, pros, drag 133626, AW836130, Hs 75277, hypothetical protein FU13910, pros, drag 5 133736, D49958, Hs 75819, glycopratein M6A, pros, mAb
133829, AW630088, Hs 76550, Homo sapiens mRNA, cDNA DKFZp5, ovar, diag 133860, S78296, Hs 76888, hypothetical protein MGC12702, blad, diag 133944, AW068579, Hs 7780, Homo sapiens mRNA, cDNA DKFZp5, pros, drag . 133975, C18356, Hs 295944, tissue factor pathway iπhibito, angio, pane, CTL+diag 0 133976, AI908165, Hs 169946, GATA-binding protein 3 (T-cell, breast, blad, mAb+s m 134100, AA460085, Hs 171075, replication factor C (activate, pros, diag 134110, U41060, Hs 79136, UV-1 protein, estrogen regula, breast blad, ovar, pros, mAb 134169, AI690916, Hs 178137, transducer of ERBB2, 1, breast CTL+s m 134219, NM_000402, Hs 80206, glucose-6-phosphate dehydrogen, breast, s m 5 134319, BE304999, Hs 285754, fumarate hydratase, colon, s m
134326, AW903838, Hs 81800, chondroitin sulfate proteoglyo, ovar, breast, pane, lung, diag 134348, AW291946, Hs 82065, iπterteukin 6 signal transduce, breast mAb+s m 134374, N22687, Hs 8236, ESTs, pros, drag 134390, R35528, Hs 8258, DKFZP434D1335 protein, pros, CTL+s m 0 134401, AI916662, Hs 211577, kinectin 1 (kinesin receptor), pros, breast mAb+s m
134405, AW067903, Hs 82772, collagen, type XI, alpha 1, breast, lung, ovar, headnk, CTL 134470, X54942, Hs 83758, CDC28 protein kinase 2, lung, blad, headnk, s m 134520, BE091005, Hs 349506, activated RNA polymerase II tπ ovar, s m 134529, AW411479, Hs 848, FK506-bιndιng protein 4 (59kD), breast, diag 5 134570, U66615, Hs 172280, SWI/SNF related, matrix associ, EWS, CTL+s m
134654, AK001741, Hs 8739, hypothetical protein FLJ10879, breast , diag 134666, BE391929, Hs 8752, transmembrane protein 4, breast, mAb+s m 134691, AW382987, Hs 88474, prostaglandin-endoperoxide syn, ovaπ s m 134727, X80507, Hs 84520, yes-associated protein 65 kDa, blad, drag 0 134731 , D89377, Hs 89404, msh (Drasophila) homeo box hom, blad, s m
134786, T29618, Hs 89640, TEK tyrosine kinase, endotheli, angio, s m 134824, S78723, Hs 298623, 5-hydroxytryptamιne (serotonin, blad, mAb 134856, BE281128, Hs 9030, TONDU, blad, CTL+s 134868, AB020689, Hs 90419, KIAA0882 protein, breast, diag
134924, BE294029, Hs 279903, Ras homolog eππched in brain , breast, mAb
134972, AL033527, Hs 169252, v-myc avian myelocytomatosis v, ovar, CTL+s m
134975, R50333, Hs 92186, Leman coiled-coil protein, breast drag 134989, AW968058, Hs 92381, nudix (nucleoside diphosphate , colon, drag
135073 W55956, Hs 94030, Homo sapiens mRNA, cDNA DKFZp5, angio, drag
135117, W52493, Hs 94694, Homo sapiens cDNA FLJ10561 fis, breast diag
135166, AA135867, Hs 280858, ESTs, Highly similar to A35661, pros, diag
135235, AW298244, Hs 266195 ESTs, angio, drag 135242, AI583187, Hs 9700, cyclin E1, ovar, CTL+s m
135243, BE463721, Hs 97101, putative G protein-coupled rec, colon, mAb+s m
135255, Y13645 Hs 97234, uroplakm 2, blad, mAb
135309, AI564123, Hs 355689, ADP-πbosylatioπ factor-like 5, pros, drag
135315, H81136, Hs 334604, Homo sapiens mRNA for KIAA1870, pros, drag 135389, U05237, Hs 99872, fetal Alzheimer antigen, pros, breast, colon, CTL+s m
135400, X78592, Hs 99915, androgen receptor (dihydratest, pros, mAb+s m
300254, AW183618, Hs 55610, solute earner family 30 (zinc, pros, breast, mAb+s m
300256, AW591433, Hs 298241, Transmembrane protease, senne, breast, colon, lung, ovaπ mAb+diag+s m
300318, AW444502, Hs 256982, ESTs, Weakly similar to NEL1_H, angio, CTL+diag 300605, AI218847, Hs 152670, ESTs, pros, diag
300921, AF146747, Hs 232165, polycythemia rubra vera 1, eel, pros, mAb+s m
300923, AW136372, Hs 1852, acid phosphatase, prostate, pros, s m
301042, AI659131, Hs 366053, hypothetical protein MGC2849, pros, mAb
301043, AI160316, Hs 149155, voltage-dependent aπion chaπne, pros, mAb+s m 301050, AW136973, Hs 362915, ESTs, Weakly similar to S69890, colon, lung, CTL+s m
301341, AA887801, Hs 208229, G protein-coupled receptor, breast, lung, mAb+s m
302001, AB020711, Hs 374965, KIAA0904 protein, breast , CTL+s m
302005, BE252922, Hs 123119, MAD (mothers against deeapeπta, pros, drag
302067, BE542706, Hs 222399, CEGP1 protein, breast, diag 302167, NMJ06227, Hs 283007, phospholipid transfer protein, pros, mAb
302225, NMJ07231, Hs 162211 , solute earner family 6 (neuro, pane, mAb+s m
302276, AW057736, Hs 323910, HER2 receptor tyrosine kinase , breast, mAb+s m
302290, AA179949, Hs 175563, Homo sapiens mRNA, cDNA DKFZp5 pros, breast drag
302372, AL117406, Hs 335891 , ATP-binding cassette transport, breast, pros , mAb+s m 302384, AI678059, Hs 202676, synaptonemal complex protein 2, breast, cerv, diag
302410, NM 004917, Hs 218366, kallikrein 4 (prostase, enamel, pros, drag
302468, AL133561, Hs 380155, DKFZP434B061 protein, pros, drag
302562, BE149762, Hs 48956, gap junction protein, beta 6 (, lung, blad, mAb
302881, AA508353, Hs 105314, relaxin 1 (H1), pros, diag 303295, AA205625, Hs 208067, ESTs, blad, drag
303380, AW962764, Hs 303171, olfactory receptor, family 51 „ pros, mAb
303506, AA340605, Hs 105887, ESTs, Weakly similar to Homolo, pros, breast, colon , drag
303699, BE143707, Hs 19525, hypothetical protein FU22794, pros, diag
303753, AW503733, Hs 9414, KIAA1488 protein, pros, breast, colon, CTL+s m 305503, AA759177, Hs 298148, ESTs, Weakly similar to KIAA05, pros, diag
306273, AA936290, , gb on70a01 s1 Soares_NFL_T_GBC, pros, drag
306676, AI005603, , gb ov15c10 s1 NCLCGAP GC3 Hom, lung, diag
306840, AI077477, Hs 307912, ESTs, angio, diag
309177, AI951118, Hs 326736, Homo sapiens breast cancer ant breast pros, mAb+CTL 309583, AW170035, Hs 326736, Homo sapiens breast cancer ant, breast mAb+CTL
309931, AW341683, Hs 343663, gb hd13d01 x1 Soares_NFL_T_GBC; lung, mAb
310382, AI734009, Hs 127699, KIAA1603 protein, pros, diag
310431, AI420227, Hs 366053, ESTs, Weakly similar to A46010, pros, diag 310573, AW292180, Hs 156142, ESTs, pros, diag 310636, AI814373, Hs 164175, ESTs, lung, drag
310781, AI380797, Hs 158992, ESTs, breast , diag
310955, AI476732, Hs 263912, ESTs, breast, angio, diag
311034, BE567130, Hs 311389, ESTs, Highly similar to NKGD_H, lung, mAb+s m
311166, AIB21005, Hs 118599, intron of BFF9 (GDNFRa) , breast , drag 311251, AI655662, Hs 197698, ESTs, pros, drag
311557, AF200492, Hs 211238, interleukin 1 homolog 1, lung, diag
311596, AI682088, Hs 79375, single minded (Drasophila) hom, pros, CTL
311630, AI915444, Hs 372037, ESTs, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m
311877, AA084248, Hs 372651, G protein-coupled receptor 39, ovar, angio, glio, mAb+s m 311911, R19175, Hs 169793, πbosomal protein L32, pros, diag
311928, T62216, Hs 378028, ESTs, pros, drag
312182, T94344, Hs 326263, ESTs, pros, diag
312252, AI128388, Hs 143655, ESTs, blad, diag
312319, AA906997, Hs 180780, TERA protein, colon, CTL+s m 312521 , AI263307, Hs 356901 , H2B histone family, member L, pros, breast, lung, diag
312544, AA516420, Hs 352340, ESTs, Weakly similar to I38022, breast, drag
312742, AI650363, Hs 116462, ESTs, colon, diag
312795, AW975014, Hs 26, ferrochelatase (protoporphyπa, pros, s m
312857, BE083868, Hs 126914, KIAA1430 protein, colon, pros, CTL+s m 312922, AA329256, Hs 378739, ESTs, Moderately similar to al, pros, drag
313328, AW449211, Hs 105445, GDNF family receptor alpha 1, breast , mAb+s
313513, AW298600, Hs 64313, ESTs, Weakly similar to S59501, angio, mAb+s
313556, AA628517, Hs 118502, ESTs, angio, diag
313665, AW751201, Hs 120932, ESTs, angio, diag 313774, AI916058, Hs 144583, ESTs, colon, CTL
313915, C18863, Hs 163443, intron of peπostm (OSF-2os), breast, diag 313978, AI870175, Hs 13957, ESTs, angio, drag 314078, AW129357, Hs 329700, ESTs, breast, diag 314097, AA648744, Hs 269493, ESTs, breast diag 314121, AI732083, Hs 187619, ESTs, pros, breast , diag 314171, AI821895, Hs 193481, ESTs, pros, drag
314506, AA833655, Hs 206868, Homo sapiens cDNA FLJ14056 fis, breast drag 314547, AA399272 Hs 144341, ESTs, breast , diag
314558, AI873274, Hs 370280, ESTs, breast, pros, drag 314589, AK001432, Hs 153408, Homo sapiens cDNA FLJ10570 fis, lung blad, drag 314691, AW207206, Hs 356962, ESTs, breast, pros, diag 314785, AI538226, Hs 32976, guanine nucleotide binding pro, colon, pros, drag 314907, AW971082, Hs 222886, ESTs, Weakly similar to TRHYJi pros, drag
315006, AI538613, Hs 298241, Transmembrane protease, seπne, breast, colon, lung ovar, mAb+diag+s m 315033, AI493046, Hs 146133, ESTs, colon, diag
315051, AW292425, Hs 163484, ESTs, breast, pros, blad, drag
315052, AA876910, Hs 134427, ESTs, pros, breast , drag 315196, AI367347, Hs 44898, Homo sapiens clone TCCCTA00151 , breast drag
315368, AB037745, Hs 104696, KIAA1324 protein, pros, diag 315408 AW273261, Hs 216292, ESTs, pros, diag 315634, AA837085, Hs 372254, ESTs, breast, pros, drag 315720, AA292998, Hs 163900, ESTs, blad, drag 316177, AI904982 Hs 293102, downstream of breast cancer an, breast, mAb+CTL
316442, AA760894, Hs 125350, ESTs, pros, drag 316580, AA938198, Hs 146123, poly(A) polymerase gamma breast, angio, s m 316886, AA836331, Hs 170261, ESTs, breast , drag 316943, AW014875, Hs 137007, ESTs, blad, diag 317079, BE159984, Hs 125395, ESTs, blad, mAb+s m
317140, AA885430, Hs 201925, Homo sapiens cDNA FLJ13446 fis, breast drag 317224, X73608, Hs 93029, sparc/osteonectin, cwcv and ka, pros, angio, drag 317548, BE568568, Hs 159066, ESTs, pros, CTL+s m 317803, AW664964, Hs 128899, ESTs, breast lung, ovar, pros, mAb+s m 317881, AI827248, Hs 224398, Homo sapiens cDNA FLJ11469 fis, breast lung , diag
318240, AI085377, Hs 143610, ESTs, lung, drag
318524, AK001050, Hs 159066, hypothetical protein FU10188, pros, colon, CTL+s m 318532, AW139377, Hs 127179, cryptic gene, pane, diag 318744, AI793124, Hs 144479, ESTs, breast, diag 318754, W21423, Hs 44222, CGI-90 protein, pros, diag
319080, AW967646, Hs 23023, ESTs, pros, drag 319795, AB037821, Hs 146858, protocadheπn 10, pros, glio, mAb+s m 320066, BE305242 Hs 16098, claudin 2, colon, pane, drag 320167, AA984373, Hs 90790, Homo sapiens cDNA FLJ22930 fi, breast, pros, drag 320203, AL049227, Hs 124776, downstream of cadhenn 6 (by 3, renal, ovaπ mAb+s
320211, AL039402, Hs 125783, DEME-6 protein, breast pros, CTL 320322, AF077374, Hs 139322, small proline-πch protein 3, lung, diag 320324, AF071202, Hs 139336, ATP-binding cassette, sub-fami, pros, mAb 320561, AF085808, Hs 159330, uroplakin 3, pros, blad, drag 320590, U67058, Hs 154299, Human proteinase activated rec, pros, mAb+s m 320635, N50617, Hs 80506, small nuclear πbonucleopratei, angio lung, diag 320736, AA315361, Hs 170195, bone morphogeπetic protein 7 (, ovar, mAb+diag 320796, AK001541, Hs 31218, secretory earner membrane pro, pros, colon , diag 320896, BE019924, Hs 271580, uroplakin 1B, lung, blad, ovar, headnk, mAb+diag 321023, AW294316, Hs 125608, ESTs, colon, diag
321107, AI732643, Hs 144151, downstream of breast cancer an, breast, mAb+CTL 321412, AI674383, Hs 22891, solute earner family 7 (catio, pros, mAb+s m 321441, AF107493, Hs 201675, Homo sapiens LUCA-15 protein m, pros breast , drag 321644, AW975944, Hs 237396, ESTs, breast, pros , diag 321717, AW956580, Hs 42699, ESTs, angio, diag
321906, AW270608, Hs 170195, bone morphogeπetic protein 7 (, ovaπ mAb+diag 321911, AF026944, Hs 293797, ESTs, angio, lung, blad, diag 322035, AL137517, Hs 306201, hypothetical protein DKFZp5640, breast blad, mAb 322521, AF147347, , gb Homo sapiens full length in, breast , diag 322706, AA018899, Hs 127179, cryptic gene, pane, diag
322782, AA056060, Hs 202577, Homo sapiens cDNA FLJ12166 fis, pros, drag 322818, AW043782, Hs 293616, ESTs, pros, breast, angio, glio , drag
322882, AW248508, Hs 279727, Homo sapiens cDNA FU14035 (is, breast lung, ovar, angio, blad, drag 322975, C16391, , intron of breast cancer antige, breast , mAb+CTL 323168, AL120862, Hs 124165, programmed cell death 9 (PDCD9, breast , drag
323226, AF055019, Hs 355279, Homo sapiens clone 24670 mRNA , pros, drag 323262, AL133990, Hs 190642, CEGP1 protein, breast pros, blad, diag 323287, AA639902, Hs 104215, ESTs, Moderately similar to SP, pros, drag 323332, AI829520, , gb wl19c06 x1 NCI_CGAP_Ut1 Hom, breast , diag 323335, AI655499, Hs 161712, ESTs, pros, breast mAb
323587, AI299709, Hs 131886, Homo sapiens cDNA FU22113 fi, colon, drag 323817, AA410943, , NAME OMITTED receptor kinase, breast , mAb 324261, BE069341, , gb QV3-BT0381-270100-073-c08 B, breast, drag 324295, AA434579, Hs 143691, ESTs, pros, drag 324338 AA927668, Hs 145078, regulator of differentiation (. colon, drag
324430, AA464018, Hs 335798, Homo sapiens cDNA FU23241 fi, pros, colon, diag 324432, AA464510, Hs 152812, ESTs, breast lung, pane, diag 324603, AW993522, Hs 299867, ESTs, pros, breast, diag 324617, AA508552 Hs 222874, ESTs, Weakly similar to 138022, pros, drag 324658, AI694767, Hs 129179, Homo sapiens cDNA FU13581 fis, pros , diag
324718, AI557019, Hs 116467, small nuclear protein PRAC, colon, pros, diag 324866, AI541214, Hs 46320, Small proline πch protein SPR, lung, blad, diag 324871, AI890347, Hs 271923, Homo sapiens cDNA FLJ22785 fi, colon, drag 324987, AI375572, Hs 172634, ESTs, breast, diag
325372, , , Phase 2 & 3 Exons, breast, CTL+s m
325544, , , Phase 2 & 3 Exons, breast, angio, diag
327036, , , Phase 2 & 3 Exons, lung, angio, diag 327075, , , Phase 2 & 3 Exons, breast, lung, diag
327414, , , Phase 2 & 3 Exons, angio, diag
328700, , , Phase 2 & 3 Exons, breast, angio, drag
330211, , , Phase 2 & 3 Exons, pros CTL+s m
330468, L10343, Hs 112341, protease inhibitor 3, skin der, lung, colon, blad, drag 330493, M27826, Hs 334372, endogenous retroviral protease, lung, colon, s m
330630, NM_002902, Hs 79088, reticulocalbin 2, EF-hand calc, pros, drag
330762, AW407332, Hs 13014, ADP-πbosylation factor GTPase, pros, CTL+s m
330790, AI660243, Hs 318545, Hu01 Chip Redos, pros, blad, diag
330814, AI955040, Hs 265398, PAR-6 beta (partitioning def, breast, drag 330827, AI961486, Hs 249196, ESTs, lung uter, drag
330892, AF109298, Hs 118258, prostate cancer associated pro, pros, diag
331014, AW770994, Hs 30340, hypothetical protein KIAA1165, colon, drag
331151, R82331, Hs 121602, ESTs, pros, breast , drag
331183, T40769, Hs 8469, ESTs, colon, drag 331237, W87874, Hs 25277, Homo sapiens cDNA FLJ10717fis, angio, diag
331490, AF216751, Hs 26813, CDA14, pros, drag
331578, AI246482, Hs 243010, ESTs, angio, drag
331614, N92293, Hs 206832, EST, Moderately similar to ALU, breast , diag
331811, AW885727, Hs 9914, Hu01 Chip Redos, lung, drag 331889, AA677577, Hs 380213, Homo sapiens Chromosome 16 BAC, pros, drag
331969 AA526911, Hs 82772, collagen, type XI, alpha 1, breast, lung CTL
332180, AF134160, Hs 7327, claudin 1, lung, mAb
332247, AA669097, , ESTs, pros, breast , diag
332396 AW579842, Hs 380730, hypothetical protein FLJ10697, pros, drag 332453, L42583, Hs 334309, Hu01 Chip Redos, lung, drag
332466, AB018259, Hs 118140, KIAA0716 gene product, angio, drag
332530, M31669, Hs 1735, inhibin, beta B (activin AB be, ovar, pros, diag
332535, AF167706, Hs 19280, cysteine rich repeat-coπtainm, angio, drag
332640, BE568452, Hs 344037, protein regulator of cytokines, blad, headnk, diag 332645, AA284371, Hs 118064, ESTs, breast colon, diag
332686, X69699, Hs 73149, paired box gene 8, ovaπ CTL+s m
332697, X51405, Hs 75360, carboxypeptidase E, pros, drag
332740, BE409869, Hs 286241 , Homo sapiens cDNA FLJ22698 fi, pros, diag
332798, , , C22000007 gι|12314195|emb|CAB9, pros, breast , diag 333769, , , NM_005940* Homo sapiens matrix, breast, colon, lung, mAb+diag+s m
333904, , , Chromosome 22, pros, drag
334223, , , NM_005080* Homo sapiens X-box , pros, breast, diag
334447, , , NM_012429* Homo sapiens SEC14 , pros, drag
335115, , , NM_006498* Homo sapiens lectin, pros, CTL+s m 335809, , , NM_014509* Homo sapiens kraken, breast CTL+s m
335824, , , ENSP00000249072* DJ222E13 1 (N, breast, pros, CTL+s m
335825, , , ENSP00000249072* DJ222E13 1 (N, breast, drag
335936, , , Chromosome 22, lung, diag
336034, , , NM_007172 Homo sapiens nucleop, breast angio, CTL+s m 336152, , ; NM_014246 Homo sapiens cadheπ, breast , mAb
336636, , , C22000024* gι|10645308|gb|AAG2, lung, breast, CTL+s m
338008, , , NM_005940* Homo sapiens matnx, lung, breast, colon, mAb+diag+s m
338033, , , Chromosome 22, lung, angio, drag
338158, , , NM_012399* Homo sapiens phosph, lung, angio, diag 338255, , , NM_014323* Homo sapiens zinc f, pros, breast, colon , CTL+s m
400195, , Hs 42650, NM_007057* Homo sapiens ZW101, lung, CTL+s m
400269, , Hs 253495, Eos Control, fibro, diag 400285, , , Eos Control, lung, diag 400287, S39329, Hs 181350, kallikrein 2, prostatic, pros, drag 400288, X06256, Hs 149609, integπn, alpha 5 (fibronectin, pane, pros.angio, blad, lung, mAb+s m 400290, H18836, Hs 31608, hypothetical protein FU20041, pros, colon, EWS, mAb
400294, N95796, Hs 278695, Homo sapiens prostein mRNA, co, pros, pros, mAb
400295, W72838, Hs 348419, AI905687 IL-BT095-190199-019 B, breast, diag
400298, AA032279, Hs 61635, six transmembrane epithelial a, pane, lung, headnk, stom, EWS, ovaπ mAb+CTL 400328, X87344, , transporter 2, ATP-binding cas, lung, mAb+s m
400409, AF153341, , Homo sapiens winged helix/fork, blad, CTL+s m
400419, AF084545, , Target, lung, sarc, drag
400440, X83957, Hs 83870, nebuliπ, sarc, diag
400494, , , ENSP00000238970* CIG30 (Fragme, angio, mAb 400517, , , leπgsin, stom, cerv, uter, lung, pros, colon, hepC, diag
400651, , , ENSP00000228031* COPPER CHAPER, sarc, s m
400665, , , NM_002425 Homo sapiens matnx , lung, mAb+diag+s m
400773, , , NM_003105* Homo sapiens sortil, blad, mAb
400844, , , NM_003105* Homo sapiens sortil, blad, s 400846, , , sortilin related receptor, L(D, blad, mAb+s m
400881, , , NMJJ25080 Homo sapiens hypothe, ovar, diag
401093, , , C12000586* gι|6330167|dbj|BAA8, blad, lung, CTL+s m
401234, , , mitogen activated protein kina, angio, drag
401424, , , NM_001172 Homo sapiens arginas, pros, s 401486, , , C4000647* gι|4758508|ref|NP_00, headnk, mAb
401704, , , NM_021195* Homo sapiens claudi, test, mAb
401732, , , NM_001176* Homo sapiens Rho GD, pane, drag
401747, , , Homo sapiens keratin 17 (KRT17, blad, lung, headnk, mela, diag 401760, , , Target Exon, blad, lung, headnk, esoph, diag 401780, , , NM_005557* Homo sapiens kerati, lung blad, headnk, esoph, mela, drag 401781, , , Target Exon, lung, blad, headnk, esoph, cerv, drag 401785, , , NMJ02275* Homo sapiens kerati, lung, drag 5 401797, , , Target Exon, sarc drag
401994, , , Target Exon, lung, diag 402145, , , Target Exon, test, CTL+s m 402199, , , Target Exon, test, CTL+s m 402230, , , Fgenesh predicted CYTOCHROME , blad, drag 0 402239, , , Target Exon, blad, drag
402260, , , NMJ01436* Homo sapiens fibπl blad, CTL+s m 402265, , , Target Exon, lung, drag 402305, , , C19000735* gι|4508027|ref|NP_0 blad, CTL+s 402420, , , C1000823* gι|10432400|emb|CAC1, lung, drag 5 402424, , , NM_024901 Homo sapiens hypothe, blad, CTL+s
402447, , , C1000201 gι|204416|gb|AAA02627, esoph, mAb 402474, , , NM_004079 Homo sapiens catheps, lung, colon, stom, fibro, drag 402550, , , Target Exon, fibro, drag 402604, , , Target Exon glio diag 0 402605, , , Target Exon, glio, drag
402606, , , NM_024626 Homo sapiens hypothe, ovar, breast, mAb 402680, , , Target Exon, test mAb 402777, , , C1002652* gι|544327|sp|Q04799|, blad, diag 402860, , , ENSP00000239210 DJ50O244 (nov, mela, CTL+s 5 402888, , , Target Exon, sarc, diag
402992, , , Target Exon, sarc, drag 402994, , , NM_002463* Homo sapiens myxovi, esoph, drag 403046, , , NMJ05656* Homo sapiens transm, pros, mAb 403047, , , NM_005656* Homo sapiens transm, pros, blad, colon, mAb 0 403071, , , NM_003319* Homo sapiens titin , sarc, drag
403088, , , NM_003319* Homo sapiens titin , sarc, drag 403171, , , C2001472* gι|5809678|gb|AAB418, test, drag 403328, , , Target Exon, mela, diag 403329, , , unnamed protein product [Homo , lung, diag 5 403381, , , ENSP00000231844* Ecotropie vir, blad, CTL+s m
403409, , , NM_005929 Homo sapiens antigen, mela, mAb 403433, , , NMJ01622 Homo sapiens aIpha-2, hepC, diag 403478, , , NMJ22342 Homo sapiens k esin, lung, CTL+s m 403715, , , Target Exon, lung, diag 0 403740, , , NM_001076* Homo sapiens UDP gl, pros, hepC, s m
403776, , , ENSP00000226542* Small inducib, pane, diag 403903, , , C5001632* gι|10645308|gb|AAG21, blad, CTL+s m 404029, , , NM_018936* Homo sapiens protoc, glio, mAb 404049, , , NM M8937* Homo sapiens protoc, glio, mAb 5 404210, , , NM_005936 Homo sapiens myeloid, pane, uter, cerv, lung ovar, pros, colon, stom, diag 404240, , , NM_018950 Homo sapiens major h, fibro, mAb 404253, , , NMJ21058* Homo sapiens H2B hi, lung, CTL+s m 404286, , , C6001909 gι|704441|dbj|BAA1890, pane, drag 404298, , , C6001238* gι|121715|sp|P26697|, lung, s m 0 404403, , , Target Exon, blad, diag
404440, , , NM_021048 Homo sapiens melanom, lung, blad, mAb+CTL 404866, , , ENSP00000251112* Sodium/potass, pane, s m 404877, , , NMJ305365 Homo sapiens melanom, lung, blad, CTL+s m 404927, , , Target Exon, lung, headnk, drag 5 404996, , , Target Exon, lung, headnk, esoph, diag 405001, , , interieukin enhancer binding f, sarc, diag 405025, , , Homo sapiens bone morphogeneti, angio, drag 405121, , , mitogen-activated protein kma, angio, renal, s m ,_ 405238, , , Target Exon, glio, diag 0 405239, , , oxidative 3 alpha hydroxystero, glio, s m 405451, , , Homo sapiens glutaminyl peptid, mela, s 405545, , , Target Exon, cerv, mAb 405546, , , NM_018833* Homo sapiens transp, cerv, mAb 405547, , , NM_018833* Homo sapiens transp, cerv, mela, mAb 5 405646, , , C120O0200 gι|4557225|ref|NP_00, lung, drag
405704, , , NM_001844* Homo sapiens collag, sarc, diag 405770, , , NMJ02362 Homo sapiens melanom, lung, esoph, mAb+CTL 405849, , , Target Exon, pane, diag
405932, , , C15000305 gι|3806122|gb|AAC691, blad, lung, headnk, cerv, CTL+s m 70 406081, , , Target Exon, blad, diag
406137, , , NMJ00179* Homo sapiens mutS (, lung, CTL+s m 406173, , , ENSP00000250148* Growth hormon, pane, CTL+s m 406348, , , Target Exon, breast, CTL+s m _ _ 406360, , , Target Exon, lung, headnk, drag
75 406399, , , NMJ03122* Homo sapiens seπne, blad, diag
406434, , , NM_030579* Homo sapiens cytoch, blad, diag 406467, , , Target Exon, lung, headnk, blad, drag 406506, , , Target Exon, angio, drag „ _ 406547, , , Target Exon, test, drag
80 406627, T64904, Hs 163780, ESTs, angio, CTL+s
406671, AA129547, Hs 285754, met proto-oncogene (hepatooyte, pane, mAb
406672, M26041, Hs 198253, major histocompatibility compl, fibro, mAb
406685, M18728, , gb Human nonspecific crossrex, pane, colon, blad, headnk, stom, lung, mAb+CTL 406687, M31126, Hs 352054, matnx metalloprotemase 11 (s, breast, lung, ovar, cerv, uter, pane, esoph, mela sarc, mAb+diag+s m
406690, M29540, Hs 220529, carcmoembryonie antigen relat, lung, headnk, pane, stom, blad, colon, cerv, mAb+CTL
406706, X03740, Hs 231581, myosin, heavy polypeptide 1, s, sarc, diag
406850, AI624300, Hs 172928, collagen, type I, alpha 1, sarc, CTL+s m 5 406906, Z25424, , gb H sapiens protein seπne/th, blad, lung, s m
406937, U14622, , gb Human traπsketolase-like pπ test, s m
406967, M24349, , gb Human parathyroid hormone I, lung, CTL+s m
406974, M57293, , gb Human parathyroid hormone π lung, blad, drag
407013, U35637, Hs 83870, gb Human nebulin mRNA, partial, sarc, drag 0 407034, U84540, , gb Human dystrobrevin isoform , glio, diag
407103, AA424881, Hs 256301, hypothetical protein MGC13170, pros, diag
407118, AA156790, Hs 262036, ESTs, Weakly similar to Z223_H, pros, drag
407122, H20276, Hs 31742, ESTs, pros, diag
407137, T97307, , gb ye53h05 s1 Soares fetal liv, lung, blad, ovar, pros, pane, headnk, diag 5 407168, R45175, Hs 117183, ESTs, pros, breast, coton, drag
407178, AA195651, Hs 352312, AP-2 beta transcnption factor, breast , CTL+s
407202, N58172, Hs 109370, ESTs, pros, drag
407216, N91773, Hs 348385, lysyl oxidase, pane, drag
407242, M18728, , gb Human nonspecific crossrex, pane, coton, blad, headnk, stom, lung, ovar, cerv, mAb 0 407244, M10014, , fibrinogen, gamma polypeptide, lung, diag
407245, X90568, Hs 172004, titin, sarc, diag
407251, U67611, Mm 29182, traπsaldolase 1, pros, s m
407252, AA659037, Hs 163780, ESTs, angio, CTL+s m
407276, AI951118 Hs 326736, Homo sapiens breast cancer ant, breast, mAb+CTL 5 407289, AA135159, Hs 203349, Homo sapiens cDNA FLJ12149 fis, lung, diag
407366, AF026942, Hs 17518, gb Homo sapiens cιg33 mRNA, pa, ovar, hepC, stom, mela, esoph, diag 407581, R48402, Hs 173508, P3ECSL, blad, CTL+s m 407601, AC002300, Hs 37129, sodium channel, πonvoltage gat, blad, mAb 407619, AL050341, Hs 37165, collagen, type IX, alpha 2, sarc, drag 0 407634, AW016569, Hs 136414, UDP-GlcNAc betaGal beta-1,3-N-, lung, headnk, s m
407710, AW022727, Hs 23616, ESTs, test, drag 407720, AB037776, Hs 38002, KIAA1355 protein, lung, mAb 407746, AK001962, Hs 38114, hypothetical protein FU11100, lung drag 407756, AA116021, Hs 38260, ubiquitm specific protease 18, pane, lung, esoph, fibro, mela, CTL+s m 5 407758, D50915, Hs 38365, KIAA0125 gene product lung, diag
407777, AA161071, Hs 71465, εqualene epoxidase, pane, esoph, s m 407782, AA608956, Hs 112619, ESTs, Moderately similar to PU, lung, drag 407786, AA687538, Hs 38972, tetraspan 1, pros, colon, uter, stom, ovar, cerv, mAb 407788, BE514982, Hs 38991, S100 calcium binding protein A, headnk, pane, blad, lung fibro, diag 0 407818, AL021938, Hs 40154,jumonjι (mouse) homolog test, CTL+s m
407824, AA147884, Hs 9812, Homo sapiens cDNA FU14388 fis, sarc, drag 407839, AA045144, Hs 161566, ESTs, blad, headnk, mAb 407846, AA426202, Hs 40403, Cbp/p300-ιnteractιng transacti, mela, drag
407853, AA336797, Hs 40499, diekkopf (Xenopus laevis) homo, colon, stom, renal, breast, ovar, uter, cerv, drag 5 407856, AA045281, Hs 266175, phosphoproteiπ associated with, mela, diag 407872, AB039723, Hs 40735, frizzled (Drasophila) homolog , ovaπ mAb 407881, AW072003, Hs 40968, heparan sulfate (glucosamine) , pane, s m 407910, AA650274, Hs 41296, fibronectin leucine πch trans, fibro, mAb 407944, R34008, Hs 239727, desmocollin 2, lung, headnk, esoph, mAb 0 407949, W21874, Hs 247057, ESTs, Weakly similar to 210926, fibro, blad, drag
407962, AI133530, Hs 62930, ESTs, Weakly similar to S59501, angio, mAb+s m
408000, L11690, Hs 198689, bullous pemphigoid antigen 1 (, breast, pros, blad, lung, headnk, cerv, esoph, mAb+CTL 408015, AW136771, Hs 244349, epidermal differentiation comp, mela, sarc, diag _ . 408045, AW138959, Hs 245123, ESTs, breast , drag 5 408056, AA312329, Hs 42331, ephnn-A4, ovaπ diag
408063, BE086548, Hs 381047, calcmeuπn binding protein ca, pros, lung, drag 408081, AW451597, Hs 167409, intron of basic-helix-loop-hel, ovar, glio, diag 408101, AW968504, Hs 278346, CDC2-related protein kinase 7, breast, lung, stom, s m 408122, AI432652, Hs 42824, hypothetical protein FU10718, lung, drag 60 408209, NM 004454, Hs 43697, ets vaπant gene 5 (ets relate, mela, CTL+s 408296, AL117452, Hs 44155, DKFZP586G1517 protein, angio, drag 408308, AL033377, Hs 44197, hypothetical protein DKFZp564D, pane, renal, colon, mAb 408353, BE439838, Hs 44298, mitochoπdπal πbosomal protei, lung, diag 408430, S79876, Hs 44926 dipeptidylpeptidase IV (CD26, , pros, mAb 65 408522, AI541214, Hs 46320, Small prolme-πch protein SPR, lung, blad, headnk, eosph, cerv, diag 408561, AI308037, Hs 84120, hypothetical protein MGC13016, mela, CTL+s m 408570, AL046406, Hs 103483, KIAA1798 protein, angio, CTL+s m 408572, AA055611, Hs 226568, ESTs, Moderately similar to AL, lung, drag 408591 , AF015224, Hs 46452, mammaglobin 1 , breast, cerv, diag 70 408611, NM_004367, Hs 46468, chemokine (C-C motif) receptor, mela, mAb
408633, AW963372, Hs 222088, PRO2000 protein, blad, lung, headnk, pros, diag 408660, AA525775, Hs 89040, ESTs, Moderately similar to PC, ovar, pane, pros, esoph, sarc, diag 408728, AL137379, Hs 47125, hypothetical protein FU13912, test, drag 408758, NM_0O3686, Hs 47504, exoπuclease 1 , mela, CTL+s m 75 408770, AW270608, Hs 170195, bone morphogenetic protein 7 (, ovaπ mAb+diag
408771, AW732573, Hs 47584, potassium voltage-gated channe, lung, mAb 408780, D31797, Hs 652, tumor necrosis fxtor (ligand), leuk, drag 408795, AW749126, Hs 170345, hypothetical protein FU13710, ovaπ drag 408826, AF216077, Hs 48376, Homo sapiens clone HB 2 mRNA s, pane, pros, diag 80 408833, AW612232, Hs 254835, ESTs, pros, diag
408877, AA479033, Hs 130315, ESTs, Weakly similar to A47582, breast, diag 408915, NM_016651, Hs 48950, heptxellular carcinoma novel , pane, sarc, drag 408930, AA146721, Hs 334686, hypothetical protein FLJ21588, blad, CTL+s m 408962 BE386436, Hs 44317, SRY (sex determining region Y), mela, drag
408992, AA059325, Hs 30114, guanine nucleotide binding pro, lung, diag
408996, AI979168, Hs 82226, glycoprotein (transmembrane) n, mela, mAb+s m
409012, AL117435, Hs 49725, DKFZP434I216 protein, sarc, CTL+s m 409038, T97490, Hs 50002, small inducible cytokine subfa, mela, drag
400051, AA080912, , gb zn04d03 r1 Stratagene hNT n, pros, s m
409077, AA063037, Hs 66803 ESTs, lung, drag
409093, BE243834, Hs 50441, CGI-04 protein lung, drag
409123 AA063403, , gb zm04d12 s1 Stratagene corne, pros, s m 409142, AL136877, Hs 50758, SMC4 (structural maintenance o, ovar, lung, mela diag
409153, W03754, Hs 50813, hypothetical protein FLJ20022, fibro, diag
409200, AL042914 Hs 51039, KIAA0076 gene product, sarc, CTL+s m
409203, AA780473, Hs 687, cytochrome P450, subfamily IVB, fibro, blad, ovaπ diag
409228, R16811, Hs 22010, ESTs, Weakly similar to 210926, lung, mAb 409231, AA446644, Hs 692, GA733-2 antigen, epithelial gl, pros, ovar, breast, uter, pane, colon, stom, mAb
409243, AB037761, Hs 51743, KIAA1340 protein, test, diag
409262, AK000631, Hs 52256, hypothetical protein FU20624, pros, CTL+s
409264, NMJ14937, Hs 52463, KIAA0966 protein, mela, CTL+s m
409269, AA576953, Hs 22972, steroid 5 alpha-reductase 2-lι, breast, ovar, lung, pane, uteπ mAb 0 409327, L41162, Hs 53563, collagen, type IX, alpha 3, colon, pane, sarc, CTL+s m
409340, BE174629, Hs 321130, hypothetical protein MGC2771, mela, CTL+s m
409342, AU077058, Hs 54089, BRCA1 associated RING domain 1, test, CTL+s m
409348, AI401535, Hs 146090, ESTs, renal, glio, drag
409361, NMJJ05982, Hs 54416, sine oculis homeobox (Drosophi, blad, lung, pros, CTL+s m 5 409389, AB007979, Hs 301281, Homo sapiens mRNA, chromosome , glio, diag
409395, U46745, Hs 336678, dystrobrevin, alpha, glio, drag
409402, AF208234, Hs 695, cystatin B (stefin B), blad, drag
409415, AA579258, Hs 6083, Homo sapiens cDNA FU21028 fi, mela, diag
409421, AA199883, Hs 67624, ESTs, test, diag O 409430, R21945, Hs 346735, splicing factor, arginine/seπ, mela, diag
409432, D49372 Hs 54460, small inducible cytokine subfa, stom, esoph, drag
409433, AA074382, Hs 135255, ESTs, glio, sarc, drag 409509, AL036923, Hs 322710, ESTs, angio, drag
409512, AW979187, Hs 293591, melanoma differentiation assoc, mela esoph, CTL+s m 5 409542, AA503020, Hs 36563, hypothetical protein FU22418, breast, ovaπ diag
409582, R27430, Hs 271565, ESTs, lung, diag
409601, AF237621, Hs 80828, keratin 1 (epidermolytc hypeπ headnk, mela, sarc, CTL+s m 409633, AW449822, Hs 55200, ESTs, sarc, drag Λ 409637, AA323948, Hs 55407, Homo sapiens mRNA, cDNA DKFZp4, renal, drag 0 409638, AW450420, Hs 21335, ESTs, glio, drag
409670, AI368109, Hs 381163, KIAA1856 protein, test CTL+s 409703, NM_006187, Hs 56009, 2'-5'-olιgoadenylate synthetas, pane, esoph, mela, s m 409705, M37762, Hs 56023, bram-deπved neurotrophic fac, lung, diag 409719, AI769160, Hs 108681, Homo sapiens brain tumor assoc, lung, drag 5 409731, AA125985, Hs 56145, thy osin, beta, identified in , pros, sarc, CTL+s m
409745, AA077391, , gb 7B14E12 Chromosome 7 Fetal , ovar, renal, CTL+s m 409935, AW511413, Hs 187393, ESTs, lung, diag 409958, NM_001523, Hs 57697, hyaluroπan synthase 1, pane, ovaπ mAb 409988, N27687, Hs 334334, transcnption factor AP-2 alph, mela, drag 0 410006, AW732308, Hs 57783, eukaryotic translation initiat, test diag 410037, AB020725, Hs 58009, KIAA0918 protein, pros, diag 410044, BE566742, Hs 58169, highly expressed in cancer, n, blad, diag 410048, W76467, Hs 343874, proline oxidase homolog, test, s m 410076, T05387, Hs 7991 , ESTs, lung, pros, diag 5 410079, U94362, Hs 380757, glycogenm 2, mela, drag
410082, AA081594, Hs 158311, Musashi (Drasophila) homolog 1, pros, drag
410102, AW248508, Hs 279727, ESTs, homologue of PEM-3 [Cion, ovar, breast, blad, lung, angio, sarc, drag 410174, AA306007, Hs 59461, DKFZP434C245 protein, mela, drag 410240, AL157424, Hs 61289, synaptojanin 2, angio, drag 0 410247, AF181721, Hs 61345, RU2S, ovar, CTL+s m
410268, AA316181 , Hs 61635, six transmembrane epithelial a, pane, pros, EWS, mAb+CTL 410290, AA402307, Hs 322844, hypothetical protein DKFZp564A, mela, drag 410310, J02931, Hs 62192, coagulation factor III (thromb, pros, pane, mAb 410361, BE391804, Hs 62661, guanylate binding protein 1, i, mela, esoph, hepC, fibro, uter, drag 5 410438, AW748012, Hs 45207, hypothetical protein KIAA1335, lung, CTL+s m
410467, AF102546, Hs 63931, dxhshuπd (Drasophila) homolog, breast, colon, uter, stom, diag 410480, R97457, Hs 63984, cadhenn 13, H-cadheπn (heart, angio, mAb 410491, AA465131, Hs 64001, Homo sapiens clone 25218 mRNA , mela, esoph, drag 410530, M25809, Hs 64173, ATPase, H transporting, lysoso, ovaπ mAb 0 410553, AW016824, Hs 272068, hypothetical protein MGC14128, blad, lung, diag 410555, U92649, Hs 380136, a disintegnn and metatloprate, leuk, lung, mAb 410561, BE540255, Hs 6994, Homo sapiens cDNA FU22044 fi, lung, diag 410566, AA373210, Hs 43047, Homo sapiens cDNA FU 13585 fis, pane, drag 410600, AW575742, Hs 351676, ESTs, Moderately similar to S6, mela, mAb+s 5 410621, AA194329, Hs 172004, titin, sarc, drag
410681, AW246890, Hs 65425, calbmdin 1, (28kD), lung, diag 410687, U24389, Hs 65436, lysyl oxidase like 1, pane, diag 410733, D84284, Hs 66052, CD38 antigen (p45), pros, mAb+CTL 410763, AF279145, Hs 8966, hypothetical protein FLJ21776, pane, mAb 0 410855, X97795, Hs 66718, RAD54 (S cerevιsιae)-lιke, test CTL+s m
410867, X63556, Hs 750, fibπlliπ 1 (Marfan syndrome), pane, drag 410870, U81599, Hs 66731, homeo box B13, pros, CTL+s 410883, D43767, Hs 66742, CCL17 chemokine (TARC) (SCYA1, leuk, drag 410889, X91662, Hs 66744, twist (Drasophila) homolog (x, sarc, CTL+s m 410929, H47233, Hs 30643, ESTs, ovar, test, diag 411078, AI222020, Hs 182364, CocoaCπsp, pros, glio, breast, drag 411089, AA456454, Hs 214291, cell division cycle 2 like 1 (, lung, fibro, CTL+s m 411243 AB039886, Hs 69319, CA11, esoph, diag
411248, AA551538, Hs 69321, Homo sapiens CDNA FLJ14408 fis, blad, diag
411257, AA628967, Hs 115274, Indian hedgehog protein (IHH) , ovar, diag
411263, BE297802 Hs 69360, kinesm like 6 (mitotic centra, lung, blad, headnk, CTL+s m
411296, BE207307, Hs 10114, growth suppressor 1, sarc, dιag 411358, R47479, Hs 94761, KIAA1691 protein, mela renal, sarc, mAb
411388, X72925, Hs 69752, desmocollin 1, headnk, mela, mAb
411393, AW797437, Hs 69771, B factor, praperdm (COMPLEMEN, ovaπ drag
411558, AA102670, Hs 70725, gamma-aminobutyπc xid (GABA), pane, pros, stom, breast, uter, cerv, ovaπ mAb
411573, AB029000, Hs 70823, KIAA1077 protein, pane, headnk, lung, stom, drag 411579, AC005258, Hs 70830, U6 snRNA-associated Sm like pr, lung, diag
411732, U47924, Hs 71642, guanine nucleotide binding pro, lung, diag
411768, NM_013371, Hs 71979, interleukin 19, ovar, uter, cerv, drag
411789, AF245505, Hs 72157, Adlican, breast, pane, lung, stom, headnk, ovar, uter, esoph, sarc, diag
411825, AK000334, Hs 352415, solute earner family 39 (zinc, colon, ovaπ mAb 411828, AW161449, Hs 72290, wingless-type MMTV integration, ovar, diag
411869, W20027, Hs 23439, ESTs, angio, drag
411874, AA096106, Hs 20403, ESTs, blad, drag
411880, AW872477, , gb hm30f03 x1 NCI_CGAP_Thy4 Ho, blad, diag
411945, AL033527, Hs 92137, L-myc-2 protein (MYCL2), blad, ovaπ CTL+s m 412006, AW451618, Hs 380683, ESTs, sare, diag
412026, AA383618, Hs 73073, testis specific ankyπn motif , test drag
412045, AA099802 Hs 83883, transmembrane, prostate androg, pros, mAb+s m
412099, U64198, Hs 73165, interleukin 12 receptor, beta , leuk, mela, mAb
412104, AW205197, Hs 240951, Homo sapiens, Similarto RIKEN, pane, fibro, drag 412115, AK001763, Hs 73239, hypothetical protein FLJ10901, lung, blad, CTL+s m
412116, AW402166 Hs 784 Epstein Barr virus induced gen, pane, mAb
412133, U83460, Hs 380728, solute earner family 31 (copp, pros, mAb
412228, AW503785, Hs 73792, complement component (3d/Epste, mela mAb
412247, AF022375, Hs 73793, vascular endothelial growth fa, renal, glio blad, colon diag 412265, AA101325, Hs 86154, hypothetical protein FU12457, test, CTL+s m
412326, R07566, Hs 73817, small inducible cytokine A3 (h, pros, leuk, drag
412351, AL135960, Hs 73828, T-cell xute lymphocytic leuke, angio, CTL+s m
412420, AL035668, Hs 73853, bone morphogenetic protein 2, blad, glio, lung stom, angio drag
412448, L12964, Hs 73895, tumor necrosis fxtor receptor, leuk, mAb 412471, M63193, Hs 73946, endothelial cell growth fxtor, cerv, mela, esoph, diag
412490, AW803564, Hs 288850, Homo sapiens cDNA FU22528 fi, mela, diag
412519, AA196241, Hs 73980, troponin T1, skeletal, slow, sarc, diag
412530, AA766268, Hs 266273, hypothetical protein FU13346, blad, lung, drag
412564, X83703, Hs 355934, cardix ankynn repeat protein, angio, diag 412580, AA113262, Hs 17901, similarto CABLES [Homo sapien, mela, drag
412610, X90908, Hs 74126, fatty xid binding protein 6, , blad, diag
412661, N32860, Hs 24611, ESTs, Weakly similarto I54374, blad, CTL+s m
412715, NM_000947, Hs 74519, pπmase, polypeptide 2A (58kD), pros, s m
412723, AA648459, Hs 335951, hypothetical protein AF301222, lung, blad, headnk, colon, stom, uteπ diag 412755, BE144306, Hs 179891, ESTs, Weakly similar to P4HA_H, angio, s m
412811, H06382, Hs 349705, ESTs, lung, diag
412817, AL037159, Hs 74619, proteasome (prosome, mxropain, lung, s m
412843, AF007555, Hs 74624, protein tyrosine phosphatase, , pros, mAb
412856, BE386745, Hs 74631, basigin (OK blood group), mela, mAb 412926, AI879076, Hs 75061, mxrophage myπstoylated alam, mela, CTL+s m
412939, AW411491, Hs 75069, eukaryotic translation elongat, mela, renal, drag
412970, AB026436, Hs 177534, dual specificity phosphatase 1, breast, mela s m
412986, X81120, Hs 75110, caπnab oid receptor 1 (brain), glio, mAb
413004, T35901, Hs 75117, interleukin enhancer binding f; lung, diag 413011, AW068115, Hs 821, biglycan, lung, CTL+s m
413049, NM_002151, Hs 823, hepsin (transmembrane protease, pros, mAb
413095, AA494359, Hs 30715, potassium voltage-gated channe, pane, stom, renal, colon, mAb+s m
413125, BE244589, Hs 75207, glyoxalase I, pros, s m
413126, AW419203, Hs 174174, ESTs, angio, diag 413129, AF292100, Hs 104613, RP42 homolog, lung, drag
413132, NM_006823, Hs 75209, protein kinase (cAMP-depeπdent, angio, CTL+s
413142, M81740, Hs 75212, omithine decarboxylase 1, lung, s m
413163, Y00815, Hs 75216, protein tyrosine phosphatase, , pros, mAb
413171, AA318325, Hs 75219, tyrosinase-related protein 1, mela, mAb 413190, AA151802, Hs 40368, adaptor-related protein comple, mela, diag
413219, AA878200, Hs 118727, Homo sapiens cDNA FL! 13692 fis, esoph, cerv, diag
413223, AI732182, Hs 191866, ESTs, lung, drag
413268, AL039079, Hs 75256, regulator of G-protein signal!, headnk, CTL+s m
413281, AA861271, Hs 222024, transcnption factor BMAL2, lung, blad, headnk, pane, angio, diag 413313, NM_002047, Hs 293885, glyeyl tRNA synthetase, test, s m
413328, Y15723, Hs 75295, guanylate cyclase 1, soluble, , pros, s m
413335, AI613318, Hs 48442, ESTs, ovaπ drag
413364, BE536218, Hs 137516, fidgetin like 1, lung, diag
413372, H55532, Hs 349695, tubulm, alpha 2, test drag 413435, X51405, Hs 75360, carboxypeptidase E, pros, glio, pane, sarc, drag
413436, AF238083, Hs 68061, sphingosme kinase 1, sarc, s m
413472, BE242870, Hs 75379, solute earner family 1 (glial, glio, mAb
413566, AW604451, Hs 381153, sprauty (Drasophila) homolog 4, sarc, CTL+s m 413573, AI733859, Hs 149089, ESTs, lung, drag
413582, AW295647, Hs 71331, hypothetical protein MGC5350, lung, drag
413597, AW302885, Hs 117183, ESTs, pras, diag
413623, AA825721, Hs 246973, intron of Bicaudal D homolog 1, ovar, pros, drag 413691, AB023173, Hs 75478, ATPase, Class VI, type 11 B, lung mAb
413711, AW291765, Hs 75486, heat shock transcnption fxto, renal, drag
413753, U17760, Hs 75517, laminin, beta 3 (nice (125kD, lung, blad, headnk pane, cerv, esoph, coton drag
413762, AW411479, Hs 848 FK506-bmdιπg protein 4 (59kD) test drag
413778, AA090235, Hs 75535, myosin, light polypeptide 2, r, sarc, diag 413794, AF234532, Hs 61638, myosin X, mela diag
413804, T64682, , gb yc48b02 r1 Stratagene liver, blad, diag
413808, J00287, Hs 350038 Homo sapiens mRNA for caldesmo, esoph, drag
413813, M96956, Hs 75561, teratocarcinoma-denved growth, colon, diag
413833, Z15005, Hs 75573, centromere protein E (312kD), lung, CTL+s m 413842, M29383, Hs 856, interferon, gamma, leuk, drag
413869, NMJ00878, Hs 75596, interleukin 2 receptor, beta, fibro, renal, mAb
413880, AI660842, Hs 110915, interleukin 22 receptoπ pane, colon, mAb+s m
413924, AL119964, Hs 75616, seladιn-1, pros, breast, ovar, drag
413943, AW294416, Hs 144687, Homo sapiens cDNA FLJ12981 fis, blad, lung, CTL+s m 413985, AI018666, Hs 75667, synaptophysin, glio, sarc, mAb
414004, AA737033, Hs 7155, ESTs, Moderately similar to 21 , pane, mela, drag
414020, NMJ02984, Hs 75703, CCL4 Chemokine (C-C motif) lig, pros, diag
414034, U89277, Hs 305985, eariy development regulator 1 , test, CTL+s m
414035, Y00630, Hs 75716, seπne (or cysteine) prateinas, lung, cerv, headnk, blad, s m 414053, BE391635, Hs 75725, transgeliπ 2, blad, drag
414061, NM_000699, Hs 300280, amylase, alpha 2A, pancreatic, ovaπ drag 414065, AW515373, Hs 271249, Homo sapiens cDNA FLJ13580 fis, pras, diag 414085, AA114016, Hs 75746, aldehyde dehydrogenase 1 famil, pros, pane, sarc, s m 414142, AW368397, Hs 334485, hemicentin (fibulin 6), fibro, pane, sarc, drag 414161, AA136106, Hs 184852, KIAA1553 protein, test, drag
414166, AW888941, Hs 75789, N myc downstream regulated, pros, renal, drag 414217, AI309298, Hs 279898, Homo sapiens cDNA FLJ23165 fi, glio, drag 414219, W20010, Hs 75823, ALL1-fused gene from chromosom, sarc, drag 414221, AW450979, , gb Ul-H BI3-ala-a-12-0-UI s1 N, blad drag 414251, AL042306, Hs 97689, VASA protein, test, CTL+s
414259, W44633, Hs 301296, integπn, beta-like 1 (with EG, pane, drag 414334, AA824298, Hs 21331, hypothetical protein FU10036, test, drag
414359, M62194, Hs 75929, cadhenn 11, type 2, OB-cadher, breast ovar, uter, pros, colon, pane, sarc, mAb 414368, W70171, Hs 75939, undine monophosphate kinase, lung, s 414386, X00442, Hs 75990, haptoglobin, ovaπ diag
414416, AW409985, Hs 76084, hypothetical protein MGC2721, blad, lung, CTL+s m 414420, AA043424, Hs 76095, immediate eariy response 3, pane, colon, drag 414430, AI346201, Hs 76118, ubiquitiπ carboxyl-terminal es, lung, s m
414443, AU077268, Hs 76144, platelet-denved growth factoπ sarc, pane, headnk, mAb 414476, AA301867, Hs 76224, EGF-containmg fibulin like ex, angio, diag
414477, U41635, Hs 76228, amplified in osteosarcoma, sarc, drag
414509, AW161311, Hs 76294, CD63 antigen (melanoma 1 antig, mela, mAb
414521, D28124, Hs 76307, neurablastoma, suppression of, breast ovar, uter, pros, blad, pane, colon, stom, fibr, diag
414565, AA502972, Hs 183390, hypothetical protein FU13590, pros, diag 414569, AF109298, Hs 118258, prostate cancer associated pro, pros, EWS, drag
414575, H11257, Hs 375743, Homo sapiens clone IMAGE 45193, renal, drag
414595, AA641726, Hs 289015, hypothetical protein MGC4171, blad, diag
414602, AW630088, Hs 76550, Homo sapiens mRNA, cDNA DKFZpδ, pros, mAb
414683, S78296, Hs 76888, hypothetical protein MGC12702, blad, lung, test, diag 414732, AW410976, Hs 77152, minichromosome maintenance def, test, blad, drag
414761, AU077228, Hs 77256, enhancer of zeste (Drasophila), lung, blad, test CTL+s m
414776, AA155598, Hs 212839, hypothetical protein FU14195,, angio, drag
414786, AI246482, Hs 243010, Homo sapiens cDNA FU14372 fis, angio, drag
414799, AI752416, Hs 77326, insulin-like growth fxtor bin, renal, drag 414806, D14694, Hs 77329, phosphatidylseπne synthase 1, lung, mAb
414807, AI738616, Hs 77348, hydroxyprostaglaπdin dehydroge, blad, s m
414809, AI434699, Hs 77356, transfemn receptor (p90, CD7, lung, mAb+s m
414825, X06370, Hs 77432, epidermal growth fxtor recept glio, lung, renal, esoph, pane, headnk, leuk , mAb+s m
414915, NM 002462, Hs 76391, myxovirus (influenza) resistan, esoph, drag 414918, AI219207, Hs 72222, hypothetical protein FU13459, blad, CTL
414921, BE390551, Hs 77628, steroidogenic xute regulatory, breast, diag
414945, BE076358, Hs 77667, lymphocyte antigen 6 complex, , mela, mAb
414987, AA524394, Hs 294022, hypothetical protein FU14950, blad, pane, esoph, diag
414998, NM_002543, Hs 77729, oxidised low density lipoprote, fibro, ovar, pane, colon, mAb 415003, M11437, Hs 77741, kininogeπ, pane, diag
415025, AW207091, Hs 72307, ESTs, blad, drag
415091, AL044872, Hs 77910, 3-hydroxy-3-methylglutaryl Coe, lung, headnk, s m
415178, D80503, Hs 46692, ESTs, blad, drag
415214, AI445236, Hs 125124, EphB2, colon, stom, mAb 415314, N88802, Hs 5422, glycoprotein M6B, mela, mAb
415457, AW081710, Hs 7369, Homo sapiens testes specific A, fibro, ovar, uteπ CTL+s m
415511, AI732617, Hs 182362, ESTs, blad, ovar, renal, diag
415542, R13474, Hs 290263, ESTs, Weakly similar to 138022, blad, drag
415724, NMJ03580, Hs 78687, neutral sphingomyelinase (N-SM, test, CTL+s m 415752, BE314524, Hs 78776, putative transmembrane protein, endo, uter, breast, stom blad, mela mAb
415786, AW419196, Hs 257924, hypothetical protein FU13782, breast, pros, blad, diag
415787, H01463, Hs 93534, ESTs, pras, diag
415819, AU077330, Hs 360791, transcnption elongation lacto, test, CTL+s m 415829, AW450198, Hs 163742, ESTs, test, drag
415857, AA866115, Hs 127797, Homo sapiens cDNA FU11381 fis, lung, test drag 415910, U20350, Hs 78913, chemokine (C-X3-C) receptor 1, glio, mAb 415947, U04045, Hs 78934, mutS (E coli) homolog 2 (colo, test diag 415989, AI267700, Hs 351201 , ESTs, pros.ovar, blad, lung, headnk, pane, colon, sarc, diag
415992, C05837, Hs 145807, hypothetical protein FLJ13593, pros, fibro, mAb 415999, AA172179, Hs 294029, ESTs, pros, uler , drag
416018, AW138239, Hs 78977, proprotein convertase subtilis, colon, pane, lung, drag 416030, H15261, Hs 21948 ESTs, breast fibro, drag 416065, BE267931 , Hs 78996, proliferating cell nuclear ant blad, lung, headnk, mela, CTL+s m
416111, AA033813, Hs 79018, chramatin assembly factor 1, s, lung, stom, CTL+s m 416188, BE157260, Hs 79070, v-myc avian myelocytomatosis v, pros, diag 416201, AA467752, Hs 195161, ESTs, test, drag 416208, AW291168 Hs 41295, ESTs, Weakly similar to MUC2_H, lung, diag 416224, NM 002902, Hs 79088, reticulocalbin 2, EF-hand calc, ovaπ drag
416225, AA577730, Hs 188684, ESTs, Weakly similar to PC4259, pros, blad, diag 416350, AF188625, Hs 189507, phospholipase A2, group HD, test, mela, fibro, drag 416370, N90470, Hs 203697, CD38 antigen (p45), pros, glio, mAb+CTL 416373, AA195845 Hs 73680, ESTs, Weakly similar to S12658, sarc, diag 416402, NM_000715, Hs 1012, complement component 4-bιndιng, fibro, drag
416448, L13210, Hs 79339, lectin, galactoside binding, ε, ovar, colon, stom, drag 416498, U33632, Hs 79351, potassium channel, subfamily K, pane, stom, breast, ovar, colon, mAb 416539, Y07909, Hs 79368, epithelial membrane protein 1, pros, headnk, diag 416602, NM_006159, Hs 367895, Protein kinase C-binding prate, breast, drag 416640, BE262478, Hs 13406, neuron specific protein, mela, drag
416661, AA634543, Hs 79440, IGF-II mRNA binding pratem 3, blad, lung, headnk, cerv, pane, angio, drag 416773, AK000340, Hs 79828, hypothetical protein FU20333, test, CTL+s 416815, U41514, Hs 80120, UDP-N-acetyl-alpha-D-galxtosa, angio, s m 416819, U77735, Hs 80205, pιm-2 oncogene, lung, test, drag 416881, N32520, Hs 141358, ESTs, mela, drag
416929, N20535, Hs 43265, melastatm 1, mela, diag 416975, NM_004131, Hs 1051, granzyme B (granzyme 2, cytoto, mela, s m 417003, AL038170, Hs 80756, betaine-homocysteine methyltra, blad, s m 417070, Z19077, Hs 172004, titin, sarc, diag 417105, X60992, Hs 81226, CD6 antigen, fibro, mAb
417115, AW952792, Hs 334612, small nuclear πbonucleoprotei, test, CTL+s m 417124, BE122762, Hs 25338, ESTs, angio, diag 417148, AA359896, Hs 374554, hypothetical protein FU14902, pane, diag 417151, AA194055, Hs 293858, ESTs, blad, drag 417153, X57010, Hs 81343, collagen, type II, alpha 1 (pr, pros, sarc, diag
417218, AA005247, Hs 285754, met proto-oncogene (hepatocyte, lung, mAb+s m 417237, H86385, Hs 81737, palmitoyl protein thioesterase, mela s m 417259, AW903838, Hs 81800, chondroitin sulfate proteoglyo, pane, breast, drag 417275, X63578, Hs 295449, parvalbumin, blad, drag 417295, AW993524, Hs 43148, epithelial membrane protein 1, pros, diag
417308, H60720, Hs 81892, KIAA0101 gene product, lung, headnk, blad, cerv, angio, mela, sarc, drag 417312, AW888411, Hs 250811, leukemia-associated phosphopro, blad, CTL+s m 417333, AL157545, Hs 173179, bromodomain and PHD finger con, breast, diag
417355, D13168, Hs 82002, endothelm receptor type B, glio, mela, mAb 417365, D50683, Hs 82028, transforming growth fxtor, be, fibro, angio, mAb
417366, BE185289, Hs 1076, small proline nch protein 1B , lung, blad, headnk, pane, esoph, mela, drag
417370, T28651 , Hs 374466, tryptophanyl-tRN A synthetase, fibro, mela, drag
417391, AW291946, Hs 82065, interleukin 6 signal transduce, breast, mAb+s m
417400, AA663486, Hs 123072, RAB3B, member RAS oncogene fam, pros, diag 417407, AA923278, Hs 290905, ESTs, Weakly similar to protea, test, pros, s m
417409, BE272506, Hs 82109, syndeoan 1, blad, diag
417412, X16896, Hs 82112, interleukin 1 receptor, type I, fibro, pros, pane, mAb
417426, NM_002291, Hs 82124, laminin, beta 1, angio, diag
417437, U52682, Hs 82132, interferon regulatory fxtor 4, mela, CTL+s m 417512, X76534, Hs 82226, glycoprotein (transmembrane) n, lung, mela, headnk, pane, breast, mAb
417515, L24203, Hs 82237, ataxia-telangiectasia group D-, lung, headnk, blad, drag
417542, J04129, Hs 82269, progestagen-assoeiated endomet, lung, mela, drag
417592, AA204664, Hs 182437, ESTs, Weakly similarto I54383, test drag
417599, AA204688, Hs 62954, ESTs, blad, esoph, diag 417621, AV654694, Hs 82316, interferon-induced, hepatitis , esoph, diag
417696, BE241624, Hs 82401, CD69 antigen (p60, eariyT-cel, pros, mAb
417705, AW134952, Hs 175220, hypothetical protein FU14541, test, mAb
417715, AW969587, Hs 86366, ESTs, blad, lung, headnk, diag
417720, AA205625, Hs 208067, ESTs, blad, lung, esoph, headnk, diag 417750, AI267720, Hs 260523, synovial sarcoma, translocated, sarc, drag
417777, AI823763, Hs 7055, ESTs, Weakly similar to I78885, test, s m
417791, AW965339, Hs 44269, ESTs, ovar, blad, lung, headnk, CTL+s m
417801, AA417383, Hs 82582, integπn, beta-like 1 (with EG, pane, fibro, diag
417805, U38545, Hs 82587, phospholipase DI, phophatidylc, angio, s m 417831, H16423, Hs 82685, CD47 antigen (Rh related antig, ovaπ mAb
417843, W07361, Hs 22545, Homo sapiens cDNA FLJ12935 fis, pros, diag
417847, AI521558, Hs 7331, hypothetical protein FLJ22316, ovaπ drag
417849, AW291587, Hs 82733, nidogen 2, angio, headnk, diag
417874, BE616160, Hs 82829, protein tyrosine phosphatase, , pane, mAb+s m 417880, BE241595, Hs 82848, selectn L (lymphocyte adhesio, mela, mAb
417886, AA214584, , ESTs, test ovar, diag
417900, BE250127, Hs 82906, CDC20 (cell division cycle 20„ lung, stom, test, blad, headnk, cerv, esoph, CTL+s m
417911, AA333387, Hs 82916, chaperonin containing TCP1, su, test, diag 417944, AU077196, Hs 82985, collagen, type V, alpha 2, sarc, drag
417975, AA641836, Hs 30085, hypothetical protein FU23186, colon, stom, lung, mAb
417976, BE565892, Hs 83077, interleukin 18 (interferan-gam, colon, stom, fibres, drag 418004, U37519, Hs 87539, aldehyde dehydrogenase 3 famil, lung, headnk, esoph, s m 418036, Z37976, Hs 83337, latent transforming growth fx, angio, diag
418054, NM_002318, Hs 83354, lysyl oxidase-like 2, lung, angio, test sarc, drag
418067, AI127958, Hs 83393, cystatin BM, headnk pane, blad, drag
418068, AW971155, Hs 293902, ESTs, Weakly similar to ISHUSS, blad, s m
418113, AI272141, Hs 83484 SRY (sex determining region Y), blad, breast, uter, colon, lung, ovar, glio, test, sarc, CTL+s m 418134, AA397769, Hs 86617, ESTs, test, diag
418140, BE613836 Hs 83551, microfibrillar-associated prat, lung, headnk, esoph, ovar, sarc, drag
418156, W17056, Hs 83623, nuclear receptor subfamily 1, , fibro, mAb+s m
418203, X54942, Hs 83758, CDC28 protein kinase 2, lung, blad, test, mela, stom, s m
418216, AA662240, Hs 283099, AF15q14 protein, headnk, lung, blad, diag 418245, AA088767, Hs 83883, transmembrane, prostate androg, pane, mAb+s m
418283 S79895, Hs 83942, cathepsin K (pycnodysostosis), breast, cerv, ovar, uter, pros, headnk, lung, pane, colon, stom, dιι
418318, U47732, Hs 84072, transmembrane 4 superfamily me, pane, pros, colon, stom, omuc, mAb
418322, AA284166, Hs 84113, cyclin-dependent kinase inhibi, headnk, lung, blad, s m
418338, NM_002522, Hs 84154, neuroπal pentraxin I, sarc, diag 418339, AA639902 Hs 104215, ESTs, Moderately similar to SP, pros, drag
418345, AJ001696, Hs 241407, seπne (or cysteine) protemas, cerv, lung, s m
418371, M13560, Hs 84298, CD74 antigen (invaπant polype, renal, mAb
418379, AA218940 Hs 137516, fidgetin-like 1, lung, drag
418394, AF132818, Hs 84728, Kruppel like fxtor 5 (intesti, pane, CTL+s m 418396, AI765805, Hs 26691, SLC2A12 Solute carπerfamily , pros, mAb
418397, NMJJ01269, Hs 84746, chromosome condensation 1, lung, drag
418389, AF131781, Hs 84753, hypothetical protein FLJ12442, test blad, sarc, drag
418406, X73501, Hs 84905, cytokeratin 20, blad, colon, drag
418432, M14156, Hs 85112, insulin like growth fxtor 1 (, pros, fibro, diag 418460, M26315, Hs 85258, CD8 antigen, alpha polypeptide, fibro, mAb
418462, BE001596, Hs 85266, integπn, beta 4, lung, blad, cerv, headnk, ovaπ mAb
418543, NM_005329, Hs 85962, hyaluronan synthase 3, blad, lung, mAb
418576, AW968159, Hs 302740, Epithelial calcium channel 2, , pros, mAb+s m
418610, AW245993, Hs 32417, hypothetical protein MGC2742, pros, drag 418641, BE243136, Hs 86947, a disintegnn and metaltoprote, cerv, lung, pane, blad, headnk, stom, mAb
418655, AA226354, Hs 111240, ESTs, pros, drag
418661, NM_001949, Hs 1189, E2F transcnption fxtor 3, ovar, lung, mela, CTL+s m
418663, AK001100, Hs 41690, desmooollin 3, lung, blad, headnk, cerv, esoph, mAb
418683, U90908, Hs 87241, hypothetical protein from cion, angio, CTL+s m 418686, Z36830, Hs 87268, annexm A8, blad, lung, drag
418693, AI750878, Hs 87409, thrombospondin 1, angio, pane, drag
418696, AW959433, Hs 326290, hypothetical protein FU12581, test, diag
418739, AA310964, Hs 88012, SHP2 interacting transmembrane, mela, diag
418756, AA252254, Hs 226949, ESTs, test , drag 418825, AA228881, Hs 22394, hypothetical protein FU10893, angio, drag
418829, AA516531, Hs 55999, NK homeobox (Drasophila), fami, pros, diag
418882, NM_004996, Hs 89433, ATP-binding cassette, sub-fami, ovar, pros, breast, lung, diag
418883, BE387036, Hs 1211, xid phosphatase 5, tartrate r, fibro, s m
418888, AU076801, Hs 89436, cadhenn 17, LI cadhenn (live, colon, stom, ovar, uter, pane, mAb+s m 418918, X07871, Hs 89476, CD2 antigen (p50), sheep red b, mela, fibro, mAb
418932, L34059, Hs 89484, cadhenn 4, type 1, R-cadheπn, glio, mAb
418941, AA452970, Hs 239527, E1B-55kDa-assocιated protein 5, angio, blad, diag
418968, NM_O00078, Hs 89538, cholesteryl ester transfer pro, mela, drag
418994, AA296520, Hs 89546, εelectin E (endothelial adhesi, pros, angio, mAb 419038, AW134924, Hs 58290, ESTs, pros, drag
419073, AW372170, Hs 183918, transmembrane receptor Unc5H2 , ovar, renal, blad, lung, mAb
419078, M93119, Hs 89584, insulmoma-asεociated 1, blad, lung, pane, sarc, drag
419079, AW014836, Hs 18844, ESTs, esoph, lung, stom, colon, drag 419086, NM_000216, Hs 89591, Kallmaπn syndrome 1 sequence, fibro, diag 419092, J05581, Hs 89603, mucin 1, transmembrane, breast, pane, lung, blad, fibro, mAb
419222, AD001528, Hs 89718, spermine εynthase, pros, s m
419223, X60111, Hs 1244, CD9 antigen (p24), breast, pros, ovaπ mAb 419231, AL046294, Hs 136245, ESTs, Weakly similar to T17227, fibro, drag 419261, X07876, Hs 89791, wingless-type MMTV integration, pane, drag 419264, AA877104, Hs 293672, ESTs, Weakly similarto ALUB_H, pros, diag
419290, AH 28114, Hs 112885, spinal cord-denved growth fx, pane, drag
419356, AI656166, Hs 7331, hypothetical protein FU22316, uter, ovar, diag
419359, AL043202, Hs 90073, chromosome segregation 1 (yeas, lung, blad, test drag
419440, AB020689, Hs 90419, KIAA0882 protein, breast, diag 419485, AA489023, Hs 99807, ESTs, Weakly similar to uπname, mela, diag
419490, NM_006144, Hs 90708, granzyme A (granzyme 1, cytoto, fibro, s m
419519, AI198719, Hs 176376, ESTs, mela, drag
419551, AW582256, Hs 91011, anteπor gradient 2 (Xenepus I, pane, pros, breast, drag
419559, Y07828, Hs 91096, nng finger protein, blad, colon, stom, CTL+s m 419568, AB026116, Hs 283078, hOAT4, renal, mAb
419569, AI971651, Hs 91143, jagged 1 (Alagille syndrome), headnk, lung, diag
419628, H67546, Hs 49768, ESTs, mela, sarc, drag
419667, AU077005, Hs 92208, a disintegnn and metalloprote, breast, cerv, angio, mAb
419693, AA133749, Hs 301350, FXYD domain-containing ion tra, pros, breast, ovar, pane, lung, mAb 419721, NM_001650, Hs 315369, aquapoπn 4, glio, lung, fibro, mAb
419743, AW408762, Hs 5957, Homo sapiens clone 24416 mRNA , blad, headnk, diag
419749, X73608, Hs 93029, εparc/osteonect , cwcv and ka, pros, pane, lung, drag
419752, AA249573, Hs 152618, ESTs, Moderately similar to ZN, lung, drag 419839, U24577, Hs 93304, phospholipase A2, group VII (p, pros, lung drag
419870, AW403911, Hs 266175, phosphoprotein associated with, mela, drag
419875, AA853410, Hs 93557, proenkephalin, sarc, diag
419948, AB041035, Hs 93847, NM_016931 Homo sapiens NADPH o, angio, mAb 419956, AL137939 Hs 40096, cadhenn 19, type 2 mela mAb
419968, X04430, Hs 93913, interleukin 6 (interferon, bet, lung, pane, esoph, drag
419981, AA897581, Hs 128773, ESTs, angio, diag
420005, AW271106, Hs 133294, ESTs, lung, test, blad, colon, diag
420062, AW411096, Hs 94785, TGF(beta) induced transcπptio, test CTL+s m 420067, T52431 , Hs 94795, Homo sapiens mRNA, cDNA DKFZpδ, sarc, drag
420137, AA306478, Hs 95327, CD3D antigen, delta polypeptid, fibro, mAb
420154, AI093155, Hs 95420, G antigen family C 1 protein (, pros, leio, CTL+s m
420174, AI824144, Hs 199749, ESTs, angio, CTL+s m
420208, BE276055, Hs 95972, silver (mouse homolog) like, mela, sarc, mAb 420209, AA256444, Hs 126485, hypothetical protein FLJ12604,, angio, drag
420218, AW958037, Hs 381105, πbosomal protein L4, mela, pros, diag
420255, NM_007289, Hs 1298, membrane metallo-endopeptidase, pros, mAb
420256, U84722, Hs 76206, cadhenn 5, type 2, VE-cadheπ, angio, fibro, mAb 420267, N37030, Hs 173337, ESTs, mela, εarc, drag 420281, AI623693, Hε 323494, Predicted cation efflux pump, lung, blad, ovar, pane, mAb
420301, AA767526, Hs 22030, paired box gene 5 (B-cell line, mela, drag 420338, AA825595, Hs 88269, Homo sapiens, clone MGC 17339,, mela, mAb 420340, NMJ00734, Hs 97087, CD3Z antigen, zeta polypeptide, fibro, mAb 420344, BE463721, Hs 97101, putative G protein-coupled rec, colon, pros, blad, headnk, pane, stom, ovar, mAb 420347, AL033539, Hs 97124, Human DNA sequence from clone , test drag
420360, U83171, Hs 97203, small inducible cytokine subfa leuk, diag 420367, AA259090, Hs 257028, ESTs, test, drag 420376, AL137471, Hs 97266, protocadheπn 18, sarc, mAb+s m 420378, NM_014143, Hs 97269, B7-H1 protein, leuk, mAb 420380, AA640891, Hs 102406 ESTs, lung, diag
420424, AB033036, Hs 97594, KIAA1210 protein, pros, diag
420462, AF050147, Hs 97932, choπdromodulin I precursoπ lung, EWS, sarc, mAb
420474, L09753, Hs 1313, tumor necrosis fxtor (ligand), leuk, mAb
420544, AA677577, Hs 380213, Homo sapiens Chromosome 16 BAC, pras, drag 420576, AA297634, Hs 54925, KIAA1858 protein, sarc, drag
420596, NM_002692, Hs 99185, polymerase (DNA directed), eps, test, CTL+s m
420633, NM 014581, Hs 274480, odorant-bmdiπg protein 2B (OB, breast, endo, diag
420656, AA279098, Hs 187636, ESTs, fibro, drag ,
420710, NMJ07009, Hs 99875, zona pellucida binding protein, test, drag 420729, AW964897, Hs 290825, ESTs, pros, diag
420757, X78592, Hs 99915, androgen receptor (dihydrotest pros, mAb+s m
420759, T11832, Hs 127797, Homo sapiens cDNA FU11381 fis, test, diag
420783, AI659838, Hs 99923, lectin, galxtoside-bind g, ε, lung, blad, headnk, drag
420789, AI670057, Hs 199882, ESTs, renal,, diag 420859, AW468397, Hs 100000, S100 calcium-binding protein A, sarc, drag
420908, AL049974, Hs 100261 , Homo sapiens mRNA, cDNA DKFZp5, pane, drag
420923, AF097021, Hs 273321, differentially expreεsed in he, blad, colon, diag
420931, AF044197, Hs 100431, small inducible cytokine B sub, breast, lung, mela, diag
420981, L40904, Hs 100724, peroxisome proliferative xtiv, colon, mAb+s 421016, AA504583, Hs 101047, transcnption factor 3 (E2A im, test CTL+s
421044, AF061871, Hs 101302, Human DNA sequence from clone , pane, drag
421059, AI654133, Hs 356247, thyroid receptor interxting p, pros, mAb+s m
421064, AI245432, Hs 101382, tumor necrosiε fxtor, alpha-i, blad, uteπ drag
421070, AA283185, Hs 19327, ESTs, blad, drag 421100, AW351839, Hs 124660, Homo sapiens cDNA FU21763 fi, blad, drag
421133, AA814971, Hs 26410, ESTs, lung, diag
421154, AA284333, Hs 287631, Homo sapienε cDNA FU14269 fis, BPH, diag
421155, H87879, Hs 102267, lysy! oxidase, headnk, pane, renal, sarc, diag 421218, NM_000499, Hs 72912, cytochrome P450, subfamily I (, blad, angio, drag 421233, AA209534, Hs 284243, tetraspan NET-6 protein, pros, breast, ovaπ mAb
421241, X91817, Hs 102866, traπsketolase-like 1, test, s m
421302, T34462, Hs 103291, neuπtin, uter, endo , diag
421305, BE397354, Hs 324830, diptheπa toxin resistance pro, ovar, diag
421307, BE539976, Hs 103305, Homo εapienε mRNA, cDNA DKFZp4, breast, lung, angio, test sarc, drag 421341, A 243212, Hs 279611, deleted in malignant brain turn, pane, lung, diag
421350, AW301608, Hs 278188, ESTs, Moderately similar to 15, test, diag
421373, AA808229, Hs 222088, ESTs, blad, diag
421433, AI829192, Hs 22380, ESTs, pros, drag
421451, AA291377, Hs 50831, ESTε, ovar, blad, lung, drag 421458, NM_003654, Hs 104576, carbohydrate (keratan sulfate , sarc, s m
421478, AI683243, Hε 97258, ESTs, Moderately similar to S2, ovar, blad, renal, uteπ diag
421481, AW391972, Hs 104696, KIAA1324 protein, pros, diag
421502, AF111856, Hs 105039, solute earner family 34 (sodi, ovar, fibro, mAb
421506, BE302796, Hs 105097, thymidme kinase 1, soluble, lung, headnk, esoph, s 421508, NM_004833, Hs 105115, absent in melanoma 2, blad, esoph, lung, mela, CTL+s
421535, AB002359, Hs 105478, phosphoπbosylformylglycinamid, test, s m
421537, BE383488, Hs 105547, neural proliferation, differen, pros, drag
421566, NM_00030g, Hs 1395, early growth response 2 (Krox-, pros, CTL+s m
421579, NMJ02975, Hs 105927, stem cell growth fxtor, lymph, sarc, mAb 421633, AF121860, Hs 106260, sorting nexin 10, mela, diag
421650, AA781795, Hs 343800, ESTs, mela, drag
421666, AL035250, Hs 1408, endothelin 3, mela, drag
421727, Y13153, Hs 107318, kynurenine 3-monooxygenase (ky, breast s m 421773, W69233, Hs 112457, ESTs, mela, esoph, sarc, diag
421777, BE562088, Hs 108196, HSPC037 protein, eεoph, cerv, lung, drag
421779, AI879159, Hs 108219, w gless-type MMTV integration, colon, ovar, diag
421798, N74880, Hs 355462, N xylsphingosme amidohydrola, fibro, s m 421814, L12350, Hs 108623, thrombospondin 2, pane, diag
421831, AA298836, Hs 22026, ESTs, similar to TRANSMEMBRAN, angio, mAb+s m
421887, AW161450, Hs 109201, CGI 86 protein, pros, mAb
421896, N62293, Hs 45107, ESTs, pros, drag
421917, AB028943, Hs 109445, KIAA1020 protein, test drag 421920, BE551245, Hs 1438, gamma-aminobutyπc xid (GABA), sarc, mAb
421924, BE514514, Hs 109606, coronm, xtiπ binding protein, fibro, drag
421948, L42583, Hs 334309, keratin 6A, lung, headnk, blad, esoph, cerv, mela, diag
421952, AA300900, Hs 98848, dynem lightchain 2B (DNLC2B), fibro, diag
421991, NMJ14918, Hs 110488, KIAA0990 protein, pane, diag 421996, AW583807, Hs 1460, glucagon, pane, diag
422002, X70070, Hs 110642, neurotensiπ receptor 1 (high a, colon, mAb
422027, AL043100, Hs 288828, fatty xid amide hydrolase, pros, s m
422033, AW245805, Hε 110903, claudin 5 (transmembrane prate, glio, mAb
422087, X58968, Hs 111301 , matnx metalloproteinase 2 (ge, sarc, drag 422089, AA523172, Hs 103135, ESTs, Weakly similar to SFR4_H, pros, drag
422094, AF129535, Hs 272027, F box only protein 5, blad, lung CTL+s m
422095, AI868872, Hs 282804, hypothetical protein FU22704, lung pane, ovar, breast, CTL+s
422099, AA156022, Hs 111518, hypothetical protein, angio, CTL+s m
422100, AI096988, Hs 111554, ADP-πbosylation fxtor-like 7, lung, esoph, CTL+s m 422110, AI376736, Hs 121555, secreted protein, acidic, cyst, pane, drag
422119, AI277829, Hs 111862, KIAA0590 gene product, blad, drag
422134, AW179019, Hs 112110, mitochondπal πboεomal protei, lung, drag
422152, AA909249, Hε 112282, εolute earner family 30 (zinc, blad, mAb+s m
422163, AF027208, Hs 112360, prominin (mouse) like 1, colon, breast, fibro, mAb 422164, NMJ14312, Hs 112377, cortic al thymocyte receptor (, blad, mAb+s m
422168, AA586894, Hs 112408, S100 calcium binding protein A, lung blad headnk, breast, mela, esoph, sarc cerv, CTL+s m
422170, AI791949, Hs 112432, anti-Mullerran hormone, uter, blad, drag
422173, BE385828, Hs 250619, phorbolin-like protein MDS019 , mela drag
422247, U18244, Hs 113602, solute carπerfamily 1 (high , blad, mAb 422278, AF072873, Hs 114218, frizzled (Drasophila) homolog , ovar, headnk, blad, cerv, lung, pane, stom, mAb
422309, U79745, Hs 114924, solute earner family 16 (mono, mela, mAb+s m
422311, AF073515, Hs 114948, cytokine receptor-like factor , lung, fibro, diag
422355, AW403724, Hs 300697, coagulation factor VII (seru , fibro, diag
422363, T55979, Hs 115474, replication fxtor C (xtivato, mela, colon, drag 422398, AI476149, Hs 334489, hypothetical protein FLJ21992, fibro, CTL+s m
422406, AF025441, Hs 116206, Opa-interxtmg protein 5, blad, lung, drag
422420, U03398, Hs 1524, tumor necrosiε fxtor (ligand), coton, pane, stom, leuk, mAb
422423, AF283777, Hs 116481 , CD72 antigen, spleen, leuk, mAb
422440, NM_004812, Hs 116724, aldo-keto reductase family 1, , lung, headnk, s m 422487, AJ010901, Hs 198267, mucin 4, trxheobroπohial, lung, headnk, pane sarc, drag
422532, AL008726, Hs 118126, protective protein for beta-ga, renal, mela, s m
422565, BE259035, Hε 118400, εinged (Droεophila) like (sea , pane, test, mela, diag
422573, AW297985, Hs 295726, integnn, alpha V (vitronecti, pane, mAb+s m
422596, AF063611, Hs 118633, 2'-5'-olιgoadenylate synthetas, esoph, mela, s m 422603, BE242587, Hs 118651 , hematopoietically expressed ho, angio, CTL+s
422633, X56832, Hs 118804, enolase 3, (beta, muscle), εarc, s m
422658, AF231981, Hs 250175, homolog of yeast long chain po, pros, drag
422689, AW856665, Hs 299797, gb RC3-CT0297-290100-013-d03 C, test, drag
422726, U11690, Hs 1572, fxiogeπital dysplaεia (Aarεko, test, drag 422728, AW937826, Hs 103262, MAD (mothers against decapenta, pros, drag
422789, AK001113, Hε 120842, hypothetical protein FU10251, test, CTL+s m
422835, BE218705, Hs 121378, metallothioneiπ like 5, testis, breast, drag
422871, AL031228, Hs 121509, collagen, type XI, alpha 2, sarc, drag
422887, AI751848, Hs 49215, ESTs, sarc, CTL+s m 422938, NM_001809, Hs 1594, centromere protein A (17kD), lung, test CTL+s m
422963, M79141, Hs 13234, ESTs, lung, pane, diag
422997, BE018212, Hs 122908, DNA replication fxtoπ lest, CTL+s m
423017, AW178761, Hs 227948, seπne (or cysteine) protemas, blad, headnk, mela, mAb+diag
423052, M28214, Hε 123072, RAB3B, member RAS oncogene fam, pros, drag 423189, M59371, Hs 171596, EphA2, colon, ovaπ mAb
423196, AK001866, Hs 125139, hypothetical protein FU11004, fibro, CTL+s
423198, M81933, Hs 1634, cell division cycle 25A, test, CTL+s m
423201, NM_000163, Hs 125180, growth hormone receptoπ pros, mAb
423217, NMJ00094, Hs 1640, collagen, type VII, alpha 1 (e, lung, esoph, drag 423271, W47225, Hs 126256, interleukin 1, beta, blad, stom, esoph, drag
423309, BE006775, Hs 126782, sushi repeat protein, lung, colon, drag
423354, AB011130, Hs 127436, calcium channel, voltage-depen, test, fibra, mAb
423387, AJ012074, Hs 348500, vasoxtive intestinal peptide , pros, mAb
423397, NMJ01838, Hs 1652, chemokine (C-C motif) receptor, blad, mela, mAb 423412, AF109300, Hs 351615, proεtate cancer aεεociated pro, pros, diag
423422, AC005175, Hs 128425, NY-REN-24 antigen, glio, mAb+CTL
423445, NM_014324, Hs 128749, alpha-methylxyl-CoA racemase, pras, s m
423453, AW450737, Hs 128791, CGI-09 protein, lung, CTL+s m
423458, AI204212, Hs 351113, ESTs, test, CTL+s m 423511, AF036329, Hs 129715, gonadotrapm-releasing hormone, lung, drag
423515, AA327017, Hs 176594, ESTs, ovaπ drag
423541, AA296922, Hs 129778, seπne protease inhibitor, Kaz, colon, pane, diag
423575, C18863, Hs 163443, intron of penostin (OSF-2os), headnk, breast, pane, lung, fibro, esoph, drag 423605, AF047826, Hs 129887, cadhenn 19, type 2, mela, mAb 423642, AW452650, Hs 157148, hypothetical protein MGC13204, lung, drag 423662, AK001035, Hs 130881, B-cell CLL/lymphoma 11A (zinc , lung, diag 423685, BE350494, Hs 49753, uveal autoantigen with coiled , pane, uter, colon, CTL+s m 423725, AJ403108, Hs 132127, hypothetical protein LOC57822, lung, headnk, blad, drag 423739, AA398155, Hs 97600, ESTs, breast, ovar, pane, drag 423761, NMJ06194, Hs 132576, paired box gene 9, headnk, CTL+s m 423765, R23~858, Hs 143375, Homo εapiens, clone IMAGE 3840, test, drag 423778 Y09267, Hs 132821, flavin containing moπooxygeπas, fibro, s m 423779, AW071837, Hs 57971 , TRANSCRIPTION FACTOR HES 5, glio, drag 423787, AJ295745, Hs 236204, nuclear pore complex protein, test, esoph, drag
423798, AF047033 Hε 132904, solute earner family 4, sodiu, angio mAb
423799, AW026300, Hs 132906, 19A24 protein, mela, mAb
423849, AL157425, Hs 133315, Homo sapiens mRNA, cDNA DKFZp7, lung, drag 423887, AL080207, Hs 134585, DKFZP434G232 protein headnk, lung, drag 423899, NM 01427, Hs 134989, engrailed homolog 2, mela, CTL+s m 423905, AW579g60, Hs 135150, lung type-l cell membrane asso, test, mAb 423909, AJ223183, Hs 135194, immunoglobulin superfamily, me, test, drag 423934, U89995, Hs 159234, forkhead box E1 (thyroid trans, lung, CTL+s m 424001, W67883, Hs 137476, paternally expressed 10, breast, ovar, drag
424012, AW368377, Hs 137569, tumor protein 63 kDa with stro, lung blad, headnk, esoph, drag
424036, AA770688, Hs 348495, H2A histone family, member L, pane, ovaπ CTL+s m
424054, AA334511 , Hs 26638, membrane spanning 4-domaιns, ε, pros, fibro, mAb
424078, AB006625, Hs 139033, paternally expresεed 3, ovar, uter, CTL+ε 424081, NM.006413, Hs 139120, πboπuclease P (30kD), test, s m
424098, AF077374, Hs 139322, small prolme-πch protein 3, lung, blad, headnk, esoph, cerv, diag
424125, M31669, Hs 1735, inhibin, beta B (xtivin AB be, ovar, pros, diag
424144, AA454033, Hs 41644, AKAP-associated sperm protein, fibro, diag
424153, AA451737, Hs 141496, MAGE-like 2, mela, CTL+s m 424165, AW582904, Hs 142255, islet amyloid polypeptide, pane mAb
424212, NM 005814, Hε 143131, glycoprotem A33 (traπsmembraπ, colon, stom, ovaπ mAb
424218, AF031824, Hs 143212, cystatin F (leukocystatm), mela fibro, drag
424244, AV647184, Hs 143601, hypothetical protein hCLA iso, blad, drag
424252, AK000520, Hε 143811, hypothetical protein FU20513, colon, εtom, diag 424264, D80400, Hs 239388, Human DNA sequence from clone , blad, mAb
424308, AW975531, Hs 154443, minichromosome maintenance def, blad, lung, test, drag
424310, AA338648, Hs 50334, testes development-related NYD, fibro, drag
424332, AA338919, Hε 101615, ESTs, pros, drag
424339, BE257148, Hs 145416, endoglyoan, pros, lung, drag 424343, AW956360, Hs 4748, adenylate cyclase xtivating p, glio, ovar, uteπ mAb
424364, AW383226, Hs 163834, ESTs, Weakly similarto G01763, lung, blad, headnk, cerv, drag
424399, AI905687, Hs 348419, AI905687 IL-BT095-190199-019 B, breast uter, headnk, drag
424420, BE614743, Hs 146688, prostaglandin E synthase, lung, blad, s m
424440, AA340743, Hs 133208, ESTs, sarc, drag 424441, X14850, Hs 147097, H2A histone family, member X, lung, diag
424450, AL137526, Hs 147472, dynein intermediate chain 2, fibro, diag
424522, AL134847, Hs 149957, nbosomal protein S6 kinase, 9, breast, cerv, ovar, uter, blad, colon, stom, s m
424527, AW138558, Hs 334873, ESTs, Weakly similar to I54374, fibro, drag
424578, AK001973, Hs 150890, hypothetical protein, test, CTL+s m 424581, M62062, Hε 150917, catenin (cadheπn-aεεociated p, glio, ovar, uteπ mAb+s m
424586, NM_003401, Hs 150930, X-ray repair complementing def, pane, CTL+s m
424629, M90656, Hs 151393, glutamate-cysteine ligase, cat, lung, CTL+s m
424635, AA420687, Hs 115455, Homo sapiens cDNA FU14259 fis, glio, diag
424676, Y08565, Hs 151678, UDP-N-xetyl-alpha-D-galxtosa, breast, s m 424704, AI263293, Hs 152096, cytochrome P450, subfamily IIJ, renal, s m
424711, NM_005795, Hs 152175, calcitonin receptor-like, angio, mAb
424717, H03754, Hs 152213, wingless-type MMTV integration, blad, lung, headnk, drag
424800, AL035588, Hs 153203, MyoD family inhibitor, test pros, drag
424806, AA382523, Hs 105689, MSTP031 protein, angio, mAb 424834, AK001432, Hs 153408, Homo sapiens cDNA FU10570 fis, lung, blad, ovar, headnk, eεoph, cerv, uteπ drag
424846, AU077324, Hs 1832, neurapeptide Y, pros, drag
424897, D63216, Hs 153684, fnzzled-related protein, pane, EWS, stom, renal, drag
424902, NM_O03866, Hs 153687, inositol polyphosphate-4-phosp, pane, leuk, mela, CTL+s m
424954, NM_000546, Hs 1846, tumor protein p53 (ϋ-Fraumeni, mela, colon, CTL+s m 424971, AA479005, Hs 154036, tumor suppressing subtransfera, pane, mela, CTL+s m
424998, U58515, Hs 154138, chitinase 3-lιke 2, glio, drag
425023, AW956889, Hs 154210, EDG-1 (endothelial different!, angio, mAb
425048, H05468, Hs 164502, ESTs, lung, blad, diag
425057, AA826434, Hs 1619, xhaete-scute complex (Drosoph, glio, lung, CTL+s m 425088, AA663372, Hs 169395, hypothetical protein FU12015, glio, mela, diag
425154, NM_001851, Hs 154850, collagen, type IX, alpha 1, sarc, drag
425159, NMJ04341, Hs 154868, carbamoyl-phosphate synthetase, lung, test, s m
425200, BE255203 comp, Hs 155101, ATP synthase, H transporting, , pane, s m
425206, NMJJ02153, Hs 155109, hydroxysteroid (17-beta) dehyd, blad, mAb 425211, M18667, Hs 1867, progastncsin (pepεinogen C), fibro, esoph, pros, diag
425234, AW152225, Hs 165909, ESTs, Weakly similar to I38022, lung, angio, blad, mela, diag
425235, AA353113, Hs 105468, Homo sapiens cDNA FLJ22743 fi, angio, diag 425237, U07695, Hs 155227, EphB4, test mAb
425245, AI751768, Hs 155314, KIAA0095 gene product, lung, drag 425259, AL049280, Hs 145010, Homo sapiens mRNA, cDNA DKFZpδ, pros, diag 425262, D87119, Hs 155418, GS3955 protein, mela, renal, CTL+s 425266, J00077, Hs 155421, alpha-fetoprotein, lung, diag 425274, BE281191, Hs 155462, minichromosome maintenance def, test, diag 425289, AW139342, Hs 155530, interferon gamma-iπducible pπ mela, CTL+s m 425308, M97639, Hs 155585, receptor tyrosine kinase like , pros, sara, mAb 425367, BE271188, Hs 155975, protein tyrosine phosphatase, , fibro, drag 425371, D49441 Hs 155981, mesothelin, ovar, lung, fibro, mAb 425397, J04088, Hs 156346 topoisomerase (DNA) II alpha (, lung, blad pane, angio, test, mela esoph, CTL+s m
425427, AI652662, Hs 317432, branched chain aminotransferas, test, s m
425428, AL110261 , Hε 157211 , DKFZP586B0621 protein, pane, diag 425465, L18964 Hs 1904, protein kinase C, iota ovar, pros, colon, s m 425525, AA358883 Hs 23871, ESTs, sara, drag 425545, N98529, Hs 158295, Homo sapiens, clone MGC 12401,, sarc, diag
425555, AA359291, Hs 130767, Homo sapienε cDNA FU23553 fi, fibro, CTL+ε m
425572, AB011076, Hs 158307, undifferentiated embryonic eel, test, CTL+s m
425601, AW629485, Hs 140720, GSK-3 binding protein FRAT2, test, CTL+s m
425606 U52112, Hs 158331, reπin binding protein, mela, diag 425628, NM_004476, Hs 1915, folate hydrolase (prostate spe, pros, s m
425638, NM_012337, Hs 158450, nasopharyngeal epithelium spec, fibro, CTL+s m
425679, X05997, Hs 159177, lipase, gastnc, esoph, s m
425692, D90041, Hs 155956, N xetyltransferase 1 (arylami, breaεt, ε m
425695, NM_005401, Hs 159238, protein tyrosine phosphatase, , lung, mAb+s m 425709, AA383076, Hs 159274, outer dense fibre of sperm tai, test drag
425710, AF030880 Hs 159275, solute earner family, member , pros, mAb
425722, AI659076, Hs 97031 , hypothetical protein MGC13047, mela, diag
425726, AF085808 Hs 159330, uroplakin 3, pros, blad, diag
425769, U72513, Hs 159486, Human RPL13-2 pseudogene mRNA,, test, diag 425811, AL039104, Hs 159557, karyopheπn alpha 2 (RAG cohoπ test, drag
425849, AJ000512, Hs 296323, serum/glucocorticoid regulated, lung, headnk, ε m
425921, NMJ07231, Hε 162211, εolute earner family 6 (neuro, εtom, pane, mAb
425976 C75094, Hε 334514, NG22 protein, proε, ovaπ mAb
426027, NM M2608 Hs 1976, platelet-denved growth fxtoπ sarc, drag 426050, AF017307, Hs 166096, E74-lιke fxtor 3 (ets domain , ovar, blad, stom, CTL+s m
426059, BE292842, Hs 166120, interferon regulatory factor 7, esoph, cerv, CTL+s m
426067, AW664691, Hs 97053, ESTs, lung, drag
426088, AF038007, Hs 166196, ATPase, Clasε I, type 8B, memb, blad, lung, mAb
426094, AF034611, Hs 166206, cubilin (intrinsic fxtor-coba, renal, drag 426116, AA868729, Hs 144694, ESTs, fibro, drag
426125, X87241, Hs 166994, FAT tumor suppressor (Drosophi, colon, stom, pane, pros, renal, fibro, cerv, mAb
426156, BE244537, Hs 167382, natnuretic peptide receptor A, ovar, mAb
426158, NM 001982, Hs 199067, v-erb-b2 avian eryUiroblastic , breast, ovar, uter, pros, blad, pane, colon, fibro, mela drag
426172, AA371307, Hε 125056, ESTε, proε, drag 426174, AA547959, Hε 115838, Homo sapiens similarto Echino, breast, pros, fibro, drag
426212, S71824, Hs 167988, neural cell adhesion molecule , glio, mAb
426271, AF026547, Hs 169047, chondroitin εulfate proteoglyc, glio, drag
426274, D38122, Hε 2007, tumor necrosis fxtor (ligand), fibro, mela, mAb
426300, U15979, Hs 169228, delta-like homolog (Drasophila, ovar, sarc, mAb 426310, NM_000909, Hs 169266, πeuropeptide Y receptor Y1, breast, mAb
426312, AF026939, Hs 181874, interferon-induced protein wit, esoph, mela, drag
426320, W47595, Hs 169300, transforming growth fxtor, be, ovar, pros, blad, pane, drag
426350, NM_003245, Hs 2022, transglutaminase 3 (E polypept, cerv, s m
426363, M58524, Hs 2025, transforming growth fxtor, be, pros, diag 426370, R98288, Hs 281706, sortilin 1, sara, diag
426416, AW612744, Hs 168824, killer cell lectin like recept, fibre, mAb
426440, BE382756, Hs 169902, solute earner family 2 (fxil, lung, pane, ovar, blad, headnk, esoph, mAb
426462, U59111, Hs 169993, dermatan sulphate proteoglycan, sara, drag
426470, AA528794, Hs 128644, ESTs, mela, diag 426471, M22440, Hs 170009, transforming growth fxtor, al, headnk, renal, pane, diag
426490, NM_001621, Hs 170087, aryl hydrocarbon receptoπ pane, mAb+s m
426501, AW043782, Hs 293616, ESTs, pros, breast, glio, lung, mela, mAb
426502, Y07759, Hs 170157, myosin VA (heavy polypeptide 1, mela, diag 426534, U58096, Hs 2051, testiε εpecific protein, Y-lm, test CTL+s m 426535, AU077012, Hs 170279, ESTs, Weakly similar to ubiqui, angio, drag
426555, NM_000372, Hε 2053, tyrosiπase (oculocutaneous alb, mela, εarc, mAb
426559, AB001914, Hs 170414, paired basic ammo xid cleavi, hepC, breast, ovar, renal, drag
426575, M74826, Hs 170808, gluta ate decarboxylase 2 (pan, pane, s m
426627, AF012359, Hε 195685, ESTs, test, drag 426635, BE395109, Hs 129327, hypothetical protein MGC13057, ovaπ CTL+s m
426682, AV660038, Hs 2056, UDP glycosyltransferase 1 fami, blad, lung, s m
426691, NM_O062O1, Hs 171834, PCTAIRE protein kinase 1, ovar, CTL+s m
426696, AW363332, Hs 171844, Homo sapiens cDNA FU22296 fi, angio, mAb
426721, AA383588, Hs 288545, ESTs, Weakly similarto T29012, fibro, drag 426726, AA488915, Hs 171955, trophimπ associated protein (, test, diag
426747, AA535210, Hs 171995, kallikrein 3, (prostate εpecif; proε, diag
426752, X69490, Hs 172004, titin, sarc, diag
426759, AI590401, Hs 21213, ESTs, mela, diag
426793, X89887, Hs 172350, HIR (histone cell cycle regula, pros, CTL+s m 426828, NM_000020, Hs 172670, xtivm A receptor type II lik, angio, mAb
426866, U02330, Hs 172816, neuregulin 1, esoph, CTL+s m
426897, AW976570, Hs 97387, ESTs, lung, drag
426900, AW163564, Hs 142375, ESTs, blad, pros, mAb
426935, NM_000088, Hs 172928, collagen, type I, alpha 1, test sarc, CTL+s m 426966, AI493134, Hs 349204, sclerostin, lung, diag
426968, U07616, Hs 173034, amphiphysm (Stiff-Mann syπdro, blad, mAb+CTL
426991, AK001536, Hs 214410, Homo sapiens cDNA FLJ10674 fis, ovar, sarc, drag
427080, AW068287, Hs 301175, raε-related C3 botulinum toxin, mela, drag 427089, AB032953, Hs 173560, odd Oz ten m homolog 2 (Drosop, headnk, esoph, diag
427122, AW057736, Hs 323910, HER2 receptor tyrosine kinase , breast, mAb
427244, AA402400, Hs 178045, ESTs, esoph, drag
427260 AA663848, , gb ae70b06 s1 Stratagene schiz lung, drag 427274, NM_005211, Hs 174142, colony stimulating fxtor 1 re, pros, sarc, mAb
427298, AA400495, , ESTs, test drag
427318, AF186081, Hs 175783 zinc transporter, pros mAb
427333, AF067797, Hs 176658, aquapoπn 8, pane, colon, mAb
427344, NMJ00869, Hs 2142, 5-hydroxytryptamιne (serotonin, ovar, mAb 427356, AW023482, Hs 97849, ESTε, ovar, breast, pras, blad, lung, drag
427398, AW390020, Hs 20415, chromosome 21 open reading fra, pros, drag
427427, AF077345, Hs 177936, lectin, superfamily member 1 (, breast, drag
427441 , AA412605, Hs 293266, SPANX family, member C, lung, esoph, CTL+s m
427461, AA531527, Hs 332040, hypothetical protein MGC13010, pros, mAb 427474, U13192, Hs 2159, aggrecan 1 (chondroitin sulfat, sarc, diag
427486, AA974433, Hs 362432, fibroblast growth fxtor 4 (he, test, drag
427510, Z47542, Hs 179312, small nuclear RNA xtivatmg c, lung, CTL+s m
427515, T79526, Hs 179516, integral type 1 protein, pros, drag
427521, AW973352, , ESTs, test, drag 427528, AU077143, Hs 179565 minichromosome maintenance def, mela, CTL+s m
427535, R29543, Hs 2164, pro-platelet basic protein (in, fibro, drag
427546, AA405280, Hs 36793, hypothetical protein FLJ23188, lung, drag
427550, BE242818, Hs 311609, nuclear RNA helicase, DECD van mela, CTL+s m
427557, NM_002659, Hs 179657, plaεminogen xtivator, urokina, pane, colon, stom, ovar, cerv, blad, lung, headnk, esoph, mAb 427578, AI591305, Hs 169084, ESTs, Highly similar to TUL3_H, test drag
427583, M82962, Hs 179704, mepπn A alpha (PABA peptide , colon, mAb
427584, BE410293, Hs 179718, v-myb avian myeloblastosis vir test, CTL+s m
427585, D31152, Hs 179729, collagen, type X, alpha 1 (Sch, breast, lung, headnk, panc,stom, colon, ovar, cerv, sarc, drag 427615, BE410107, Hs 179817, CGI-82 protein, PSDR1, proε, drag 427634, AI399745, Hs 18449, hypothetical protein MGC10820, mela, sarc, drag
427647, W19744, Hs 180059, Homo sapiens cDNA FLJ20653 fis, sarc, diag
427666, AI791495, Hs 180142, calmodulm like εkin protein (, breast, cerv, blad, lung, headnk, esoph, diag
427667, AK001279, Hs 180171, Homo sapiens cDNA FU10417 fis, test, drag
427668, AA298760, Hs 180191, hypothetical protein FU14904, lung test diag 427681, AB018263, Hs 284232, tumor πecrosiε fxtor receptor, ovaπ mAb+s m
427698, AW972594, Hs 335499, ESTε, fibro, CTL+ε m
427701, AA411101, Hs 243886, nuclear autoantigenic sperm pr, lung, mAb+CTL
427715, BE245274, Hs 180428, KIAA1181 protein, pros, drag 427719, AI393122, Hs 134726, ESTs, test, blad, drag 427730, AW250549, Hs 180577, granulin, mela, drag
427786, BE407863, Hs 256871, ESTs, esoph, blad, drag
427809, M26380, Hs 180878, lipoprotein lipase, ovar, mAb
427811, M81057, Hs 180884, carboxypeptidase B1 (tisεue), breast s m
427897, NM_017413, Hε 303084, apelm, peptide ligand for APJ, angio, renal, pros, drag 427912, AL022310, Hs 181097, tumor necrosis fxtor (ligand), angio, mAb
427958, AA418000, Hs 376771, potassium intermediate/small c, pros, glio, mAb
427961, AW293165, Hs 143134, ESTs, lung, sarc, drag
428001, H97428, Hs 219907, ESTs, Moderately similar to Tπ mela, diag
428004, AA449563, Hs 151393, glutamate-cysteine ligase, cat, lung, s m 428023, AL038843, Hs 374530, Homo sapiens cDNA FU23602 fi, lung, drag
428046, AW812795, Hs 337534, ESTs, Moderately similar to 13, lung, colon , drag
428062, AA420683, Hs 98321, hypothetical protein FU14103, angio, drag
428087, AA100573, Hs 182421, tropomn C2, fast, sarc, CTL+s m
428141, D50402, Hs 182611, solute earner family 11 (prat glio, mAb 428153, AW513143, Hs 98367, SRY (se determining region Y), ovaπ drag
428169, AI928984, Hs 182793, golgi phosphoprotem 2, pros, diag
428182, BE386042, Hε 293317, ESTs, Weakly similar to GGC1_H, blad, headnk, lung, ovar, sarc, CTL+s m
428183, AW969726, Hs 98381, ESTs, Weakly similar to seπne, EWS, drag 428206, AB020643, Hs 183006, KIAA0836 protein, angio, mAb 428221, U96781, Hs 183075, ATPase, Ca transporting, cardi, sarc, ε m
428227, AA321649, Hε 2248, small inducible cytokine subfa, breast, lung, blad, ovar, headnk, fibro, colon, stom, cerv, leuk, renal, test, mela, esoph, hepC, ι
428248, AI126772, Hs 40479, ESTs, sara, diag
428293, BE250944, Hs 183556, εolute camerfamily 1 (neutπ proε, mAb
428305, AA446628, Hs 2799, cartilage linking protein 1 , sarc, drag 428329, AA426091, Hε 98453, ESTs, Moderately similar to R2, test, diag
428336, AA503115, Hs 183752, microseminoprotein, beta-, pros, drag
428355, BE256452, Hs 2257, vitronectin (serum spreading f, colon, drag
428398, AI249368, Hε 98558, ESTs, pras, breast , drag
428405, Y00762, Hs 2266, choliπergio receptor, nicotim, esoph, sarc, mAb 428423, AU076517, Hs 184276, solute camerfamily 9 (εodiu, ovaπ CTL+s m
428434, AW363590, Hs 65551 , Homo sapiens, Similar to DNA s, lung, fibro, diag
428467, AK002121, Hs 184465, hypothetical protein FU11259, fibro, mAb
428471, X57348, Hε 184510, stratifiπ, lung, headnk, colon, pane, drag
428645, AA431400, Hs 98729, ESTs, Weakly similarto 201720, lung, s m 428651, AF196478, Hs 188401, annexm A10, blad, stom, pane, drag
428667, AI375550, Hs 346868, nucleolar protein p40, homolog, fibro, uteπ drag
428722, U76456, Hs 100787, tissue inhibitor of metallopro, glio, drag
428728, NM_016625, Hs 191381, hypothetical protein, ovar, lung, BPH, CTL+s m
428771, AB028992, Hs 193143, KIAA1069 protein, lung, CTL+s m 428784, Y12851, Hs 193470, puπnergic receptor P2X, ligan, glio, mela, mAb
428800, M57627, Hs 193717, interleukin 10, fibro, drag
428801, AW277121, Hs 254881, ESTs, pros, diag
428804, AK000713, Hs 193736, hypothetical protein FU20706, mela, diag 428810, AF068236, Hs 193788, nitπe oxide synthase 2A (indu, lung, s m 428819, AL135623, Hs 193914, KIAA0575 gene product, pros, CTL+s m 428824, W23624, Hs 173059, ESTs, pane, diag 428832, AA578229, Hs 324239, ESTs, Moderately similar to ZN, pane, uter, diag 428841, AI418430, Hs 104935, ESTε, renal, drag
428848, NM_000230, Hs 194236, leptin (muπne obesity homolog, sarc, drag 428862, NM_000346, Hε 2316, SRY (sex determining region Y), pros, sarc, CTL+s m
428927, AA441837, Hs 90250, Homo sapienε hypothetical prot, fibro, mAb+diag
428928, BE409838, Hs 194657, cadhenn 1, type 1, E-cadheππ, pros, breast, stom, blad, mAb 428949, AA442153, Hs 104744, hypothetical protein DKFZp434J, sarc, drag
428957, NM_003881, Hs 194679, WNT1 inducible signaling pathw, cerv, drag 428959, AF100779, Hs 194680, WNT1 inducible signaling pathw, sarc, drag 428977, AK001404, Hs 194698, cyclm B2, test, CTL+s m
428981, BE313077, Hs 93135, ESTs, Weakly similar to ALU2_H, sarc, drag 429002, AW248439, Hs 2340, junction plakoglob , blad, CTL+s m
429010, Y18198, Hs 194725, one cut domain, family member , pane, diag
429038, AL023513, Hs 194766, seizure related gene 6 (mouse), lung, mAb
429058, AF138863, Hs 35254, hypothetical protein FLB6421, esoph, drag
429065, AI753247, Hs 29643, Homo sapiens cDNA FU13103 fis, lung, diag 429083 Y09397, Hs 227817, BCL2-related protein A1, mela, drag
429113, D28235, Hs 196384, prostaglandm-eπdoperoxide syn, angio, blad, stom, s m
429120, AK001673 Hs 196530, hypothetical protein FLJ10811, test, drag
429150, AF120103 Hs 197366, εmoothened (Drasophila) homolo, ovaπ mAb
429163, AA884766, , gb am20a10 s1 Soares_NFL_T_GBC, pros, drag 429170, NM_001394, Hs 2359, dual specificity phosphataεe 4, breast panc,stom, lung, mela, s m
429201, X03178, Hs 198246, group-specific component (vita, pane, drag
429220, AW207206, Hs 356962, ESTε, breast, pros, BPH, drag
429228, AI553633, Hs 356828, ESTs, lung, fibro headnk, esoph, diag
429259, AA420450, Hs 380088, Piakophi n, lung headnk, diag 429290, AF203032, Hs 198760, neurofilament, heavy polypepti pros, CTL+s m
429299, AI620463, Hs 347408, hypothetical protein MGC13102, pros, cerv, drag
429329, AA456140, Hs 99235, Homo sapiens panπexin 3 (PANX3, sarc, mAb
429345, R11141, Hs 199695, hypothetical protein, blad, diag
429359, W00482, Hs 2399, matrix metalloprotemase 14 (m, headnk, breast, cerv, ovar, blad, lung, esoph, mela, sarc, mAb 429413, NM_014058, Hs 201877, DESC1 protein, lung, blad, diag
429415, NMJJ02593, Hs 202097, procollagen C-endopeptidase en, sarc, diag
429423, AI016712, Hs 380983, integπn, beta 1 (fibronectin , angio, mAb
429432, AI678059, Hs 202676, synaptonemal complex protein 2, breast, cerv, drag
429441, AJ224172, Hε 204096, lipophilin B (uteroglobm fami, breast, pros, ovaπ drag 429466, M85835, Hs 12827, ESTs, glio, uter, CTL+s m
429469, M64590, Hs 380791, glycine dehydrogenase (decarbo, test s m
429486, AF155827, Hε 203963, hypothetical protein FU10339, blad, lung, headnk, test, diag
429500, X78565, Hs 289114, hexabrxhion (tenascm C, cyto, lung, glio, headnk, mela, sarc, drag
429504, X99133, Hs 204238, lipocalin 2 (oncogene 24p3) (N, ovar, lung, blad, drag 429505, AW820035, Hs 278679, a disintegnn and metaltoprote, coton, leuk, mAb
429538, BE182592, Hs 139322, small proline-πch protein 2A, lung, esoph, drag
429563, BE619413, Hs 2437, eukaryotic translation initiat lung, diag
429586, T73510, Hs 209153, angiopoietiπ like 3, hepC, CTL+s m
429597, NMJW3816, Hs 2442, a disintegnn and metalioprote, pane, colon, εtom, lung, mAb 429609, AF002246, Hs 210863, cell adhesion molxule with ho, ovar, mela, diag
429612, AF062649, Hs 252587, pituitary tumor-transforming 1, lung, blad, headnk, diag
429655, U48959, Hs 211582, myosin, light polypeptide kiπa, pros, s m
429663, M68874, Hs 211587, phospholipase A2, group IVA (c, angio, lung, s m
429664, L20433, Hs 211588, POU domain, class 4, transcπp, sarc, CTL+s m 429736, AF125304, Hs 212680, tumor necrosis fxtor receptoπ lung, mAb
429747, M87507, Hs 2490, caspase 1, apoptosis related c, colon, stom, fibro, s 429764, BE245076, Hs 216958, KIAA0194 protein, proε, mAb 429769, NM_004917, Hs 218366, kallikrein 4 (prostase, enamel, pros, s m 429784, M89796, Hs 30, membrane-spanning 4-domaιns, s, fibro, mAb 429823, AA459443, Hs 181400, ESTε, saro, drag
429859, NM_007050, Hs 225952, protein tyrosine phosphatase, , breast, mAb+s 429918, AW873986, Hs 119383, ESTs, pros, glio, drag 429921, AA526911, Hs 82772, collagen, type XI, alpha 1, headnk, pane, sarc, CTL 428983, W92620, Hs 260855, ESTs, blad, drag 429986, AF092047, Hs 227277, sine ocu s homeobox (Drosophi, lung, CTL+s m
430014, H59354, Hs 374303, xtinm, alpha 4, renal, diag
430016, NM_004736, Hs 227656, xenotropie and polytropic retπ ovar, mAb
430044, AA464510, Hs 152812, ESTs, breast, lung, pane, headnk, ovar, stom, esoph, drag
430056, X97548, Hs 228059, KRAB-associated protein 1, test, CTL+s m 430129, BE301708, Hs 233955, hypothetical protein FU20401, angio, diag
430130, AL137311, Hε 234074, Homo εapienε mRNA, cDNA DKFZp7, pros, mAb
430144, AI732722, Hs 98927, ERGL protein, ERGIC-53-lιke pr, pros, drag
430152, AB001325, Hs 234642, aquaponn 3, blad, fibro, mAb
430154, AW583058, Hs 234726, seπne (or cysteine) proteinas, pros, diag 430157, BE348706, Hs 278543, ESTs, blad, drag
430168, AW968343, Hs 145582, DKFZP434I1735 protein, blad, drag
430223, NM_002514, Hs 235935 nephrablastoma overexpresεed g, mela, drag
430226, BE245562, Hs 2551, adrenergic, beta-2-, receptor,, pros, mAb
430228, AW950939, Hs 6382, ESTs, Highly similar to T00391, glio, drag 430252, AI638774, Hs 105328, testes development related NYD, test, CTL+s m
430253, AK001514, Hs 236844, hypothetical protein FU10652, test, CTL+s m
430255, AK000703, Hs 323822, Homo sapienε mRNA for KIAA1551, test, CTL+s m
430259, BE550182, Hs 375142, RalGEF-like protein 3, mouse h, ovaπ CTL+s m 430280, AA361258, Hs 237868, interleukin 7 receptor, mela, lung, pane, stom, esoph, headnk, fibro, mAb+s m
430287, AW182459, Hs 125759, ESTs, Weakly similar to LEU5_H, test, diag
430294, AI538226, Hs 32976, guanine nucleotide binding pro, pros, drag
430337, M36707, Hs 239600, calmodulm like 3, lung drag 430354, AA954810, Hs 239784 human homolog of Drasophila Se, ovaπ drag
430378, Z29572, Hs 2556, tumor necrosis factor rxeptoπ lung fibro, breast headnk, blad, breast, colon, εtom, drag
430393, BE185030, Hs 241305, estrogen responsive B box prot, lung, drag
430396, D49742, Hs 241363, hyaluranan binding protein 2, pane, diag
430407, H23551 , Hs 30974, ESTs, pane, drag 430439, AL133561, Hs 380155, DKFZP434B061 protein, lung, test drag
430451, AA836472, Hs 297939, cathepsin B, ovar, lung, headnk, pane stom, drag
430454, AW469011, Hs 105635, ESTs, lung, drag
430476, AA447465, Hs 2563, txhykmin, precursor 1 (subst, sarc, drag
430487, D87742, Hε 241552, KIAA0268 protein, pros, drag 430491, AL109791, Hs 241559, Homo sapiens mRNA full length , ovaπ drag
430498, X02910, Hs 241570, tumor necroεiε factor (TNF sup, leuk, drag
430508, AI015435, Hs 104637, ESTs, lung, mAb+s m
430521, NM_016383, Hs 242183, HOM-TES 85 tumor antigen, test CTL+s m
430540, AW245422, Hs 106357, Homo sapiens cDNA FLJ22105fi, mela, mAb 430563, AA481269, Hs 348628, ATP-binding cassette, sub-fami, lung, drag
430594, AK000790, Hs 246885, hypothetical protein FU20783, mela, diag
430634, AI860651, Hs 26685, calcyphosine, ovar, drag
430637, BE160081, Hs 256290, S100 calcium-binding protein A, mela, diag
430647, AC003682, Hs 127988, ESTs, Weakly similar to Z211_H, test, drag 430676, AF084866, Hs 372585, gb Homo sapienε envelope prate, test, diag
430677, Z26317, Hs 359784, desmoglein 2, lung, colon, mAb
430678, AI458174, Hs 192855, ESTs, lung, drag
430686, NMJ01942, Hs 2633, desmoglein 1, lung, headnk, mela mAb
430691, C14187, Hs 157208, aπstaless related homeobox pr, EWS, ovar, pane, drag 430704, AW813091, Hs 335799, ESTs, stom, diag
430770 AA765694, Hs 123296, ESTs, mela, diag
430832, AI073913, Hs 100686, ESTs, Weakly similar to JE0350, breast, colon, ovar, uter, lung, εtom, fibro, drag
430838, N46664, Hs 169395 hypothetical protein FLJ12015, mela CTL+s m
430890, X54232, Hs 2699, glypican 1, glio, lung cerv, blad, esoph, mAb 430985, AA490232, Hs 27323, ESTs, Weakly similar to I78885, lung mAb
431009, BE149762, Hs 48956, gap junction protein, beta 6 (, lung, blad, headnk, esoph, mAb
431053, S40369, Hs 249141, Glutamate receptor subunit, glio, mAb
431070, AW408164, Hs 249184, transcnption factor 19 (SC1), blad, drag
431089, BE041395, Hs 374629, ESTs, Weakly similar to unknow, blad, lung, pros, angio, fibro, diag 431099, Y13367, Hs 249235, phosphoιπosιtιde-3-kιπase cla, pros, CTL+s m
431103, M57399, Hs 44, pleiotropfun (hepaπn binding , sarc, mela, diag
431124, AF284221, Hs 59506, doublesex and mab-3 related tπ lung, CTL+s m
431151, BE207083, Hs 366053, gb ba10d10 y1 NIH_MGC_7 Homos, pros, mAb
431164, AA493650, Hs 94367, thyroid transcnption fxtor 1 , fibro, CTL+s m 431183, NMJ306855, Hs 250696, KDEL (Lys-Aεp-Glu Leu) endopla, mela, pros, pane, colon, stom, mAb
431211, M86849, Hs 323733, gap junction protein, beta 2, , colon, blad, lung, pane, headnk esoph, mAb
431217, NM_013427, Hs 250830, Rho GTPase xtivatiπg protein , pros, CTL+s m
431221, AA449015, Hs 286145, SRB7 (suppresεor of RNA polyme, lung, CTL+s m
431222, X56777, Hs 273790, zona pellucida glycoprotein 3A, pros, diag 431250, BE264649, Hs 251377, taxol resistance associated ge, esoph, diag
431322, AW970622, Hs 376626, gb EST382704 MAGE resequences,, blad, ovar, uteπ diag 431347, AI133461, Hs 251664, insulin like growth fxtor 2 (, blad, mAb+diag 431354, BE046956, Hs 251673, DNA (cytoειπe-5-) methyltransf, test, CTL+s 431360, NM 000427, Hs 251680, loπcπn, mela, sarc, drag 431362, AI874223, Hs 293560, ESTs, angio, diag
431369, BE184455, Hs 251754, secretory leukocyte protease i, ovar, blad, drag
431384, BE158000, Hε 334372, gb MR2-HT0377-150200-202-e03 H, lung, drag
431385, BE178536, Hs 11090, membrane-spanning 4-domaιπs, s, pane, drag 431441, U81961, Hs 2794, sodium channel, nonvoltage-gat, ovar, pros, blad, mAb 431448, AL137517, Hs 306201 , hypothetical protein DKFZp5640, blad, mAb
431457, NM_012211, Hs 256297, integnn, alpha 11, headnk, mAb
431474, AL133990, Hs 190642, CEGP1 protein, breast pros, blad, diag
431494, AA991355, Hs 298312, hypothetical protein DKFZp434A, lung, diag
431512, BE270734, Hs 2795, Ixtate dehydrogenase A, pane, s m 431548, AI834273, Hs 9711, novel protein, lung, angio, pras, diag
431553, X78075, Hs 2799, cartilage linking protein 1, sarc, drag
431579, AW971082, Hs 222886, ESTs, Weakly similar to TRHY_H, pros, drag
431616, AA508552, Hs 222874, ESTs, Weakly similar to 138022, pras, pane, colon , mAb
431674, AA098901, Hs 301642, G-protein coupled receptoπ ovaπ mAb+s m 431723, AW058350, Hs 278966, Homo sapienε mRNA, cDNA DKFZpδ, fibro, drag
431728, NM_007351, Hs 268107, multimeπn, angio, diag
431808, M30703, Hs 270833, amphiregulin (sohwaπnoma-denv, breast, headnk, pane, colon, diag
431836, AF178532, Hs 271411 , beta-εite APP-cleavmg enzyme , mela, mAb
431870, AW449902, Hs 105500, ESTs, renal, diag 431890, X17033, Hs 271986, integnn, alpha 2 (CD49B, alph, blad, headnk, lung, pane, cerv, stom, mAb
431938, AA938471, Hs 54431, specific granule pratem (28 k, pane, diag
431939, AW008061, Hs 231994, ESTs, renal, colon, drag
431941, AK000106, Hs 272227, Homo sapiens cDNA FU20099 fis, cerv, glio, diag 431989, AW972870, Hs 291069, ESTs, ovaπ diag 431992, NM_002742, Hs 2891, protein kinase C, mu, pros, glio, s m
432004, BE018302, Hs 2894, plxental growth fxtor, vascu, renal, drag 432015, AL157504, Hs 159115, Homo sapiens mRNA, cDNA DKFZpδ, blad, drag 432023, AW273128, Hε 300268, EST, lung, diag 432097, X51730, Hs 2905, progesterone receptoπ blad, mAb+s m 432117, AL036195, Hs 2909, protamine 1, test, CTL+s m 432128, AA127221, Hs 66, ESTs, angio, drag
432141, BE410964, Hs 272736, nuclear receptor binding prate, test, mAb+ε m 5 432189, AA527941 , , gb nh30c04 ε1 NCI_CGAP_Pr3 Hom, pros, drag
432199, AI693815, Hs 127179, cryptic gene, pane, drag
432210, AI567421, Hs 273330, Homo sapiens, clone IMAGE 3544, ovar, lung, blad, diag 432222, AI204995, , gb aπ03c03 x1 Stratagene schiz, angio, blad, fibro, drag 432231, AA339977, Hs 274127, CLST 11240 protein, fibro, diag 0 432239, X81334, Hs 2936, matnx metalloprotemase 13 (c, blad, lung, headnk, esoph, εarc, s m
432240, AI694767, Hs 129179, Homo sapienε cDNA FLJ13581 fis, pros, drag 432305, M62402, Hs 274313, insulin like growth factor bin, cerv, drag 432374, W68815, Hs 301885, Homo sapiens cDNA FLJ11346 fis, cerv, lung, fibro, pros, drag 432407, AA221036, , gb zr03f12 r1 Stratageπe NT2 n, lung, test colon, drag 5 432415, T16971 , , ESTs, Weakly similar to A43932, ovar, pros, diag
432432, AA541323 Hs 115831, ESTs, uter, pros, drag 432435, BE218886, Hs 282070, ESTs, pros, uter, colon, stom, fibro, drag 432441 , AW292425, Hs 163484, intron of hepatocy te nuclear f, blad, fibro, pros, drag 432473, AI202703, Hs 152414, ESTs, pros, drag 0 432481, AW451645, Hs 151504, intron of collagen, type XI, a, εarc, drag
432512, NM 003284, Hs 3017, transition protein 1 (duπng h, test CTL+s m 432519, AI221311, Hs 130704, ESTs, Weakly similar to BCHUIA fibro, ovar, uter, CTL+s m 432527, AW975028, Hs 102754 ESTε, proε, uter, ovar, cer , drag 432542, AW083920, Hs 16098, claudm 2, colon, pane, drag 5 432583, AW023624, Hs 162282, potassium channel TASK-4, pota lung, mAb 432615, AA557191, Hs 55028, ESTs, Weakly similarto 154374, pros, diag 432621, AI298501, Hs 21192, ESTε, Weakly similar to T46428, pros, mAb 432629, AW860548, Hs 280658, ESTs, ovaπ diag
432653, N62096, Hs 293185, ESTs, Weakly similar to JC7328, pros lung , mAb+s m O 432666, AW204069, Hs 351118, ESTs Weakly similar to unname, test, diag
432706, NM_013230, Hs 286124, CD24 antigen (small cell lung , colon, ovar, pros, mAb+CTL 432730 AI066520, Hs 131358, ESTs, test, diag 432731, R31178, Hs 287820, fibronxtin 1, pane, fibro, drag 432788, AA521091, Hs 178499, Homo sapiens cDNA FLJ23117fi lung, ovar, CTL+s m 5 432800, BE391046, Hs 278962, AIM-1 protein, mela, pros, mAb
432842, AW674093, Hs 334822, hypothetical protein MGC4485, blad, lung, headnk, CTL+s m 432850, X87723, Hs 3110, angiotensin rxeptor 2 (AT2), leio, mAb 432855 AF017988, Hs 279565, secreted frizzled related prot, pane drag 432867, AW016936, Hs 233364, ESTs, stom, colon, diag 0 432878, BE386490, Hs 279663, Piπn, mela, CTL+s m
432887, AI926047, Hs 162859, AK056805 Homo sapiens cDNA FL, pros, drag 432938, T27013, Hs 3132, steroidogenic xute regulatory, ovar, diag 432966, AA650114, Hε 325198, ESTs, pros, drag 433012, NM_004045, Hs 279910, ATX1 (antioxidant protein 1, y, mela, diag 5 433013, AI697890, Hs 127337, axin 2 (conductin, axil), colon, CTL+s m
433043, W57554, Hs 125019, lymphoid nuclear protein (LAF-, pros, breast, drag 433068, NM_006456, Hs 288215, εialyltransferase, breast, ovar, mela, s m 433078, AW015188, Hs 121575, Homo sapiens cDNA FU12231 fis, blad, drag 433091, Y12642, Hs 3185, lymphocyte antigen 6 complex, , blad, lung, headnk, cerv, mAb O 433147, AF091434, Hs 43080, platelet deπved growth fxtoπ ovar, pane, fibro, diag 433159, AB035898, Hs 150587, kinesm like protein 2, ovar, uter, colon, blad, drag 433170, AB037816, Hs 8982, KIAA1395, angio, drag 433183, AF231338, Hs 222024, transcnption factor BMAL2, lung, diag _ _ 433228, F28212, Hs 14953, KIAA1491 protein, test CTL+s m 5 433258, AI806626, Hs 207300, ESTs, Weakly similar to ALUB_H, lung, drag
433285, AW975944, Hs 237396, ESTs, breast pros , diag
433293, AF007835, Hs 32417, hypothetical protein MGC2742, fibro, pros, stom, pane, CTL+s m 433323, AA805132, Hs 159142, ESTs, pros, drag 433334, AI927208, Hs 231958, matnx metalloprotemase 28, pane, s m 0 433336, AF017986, Hε 31386, secreted frizzled related prot, ovar, fibro, headnk, lung, pane, blad, diag
433364, AI075407, Hs 296083, ESTs, Moderately similar to 15, mela, drag
433365, AF026944, Hs 293797, ESTs, blad, drag
433376, A1249361, Hs 74122, caspase 4, apoptosis related c, angio, s m
433388, AI432672, Hs 288539, hypothetical protein FU22191, ovaπ CTL+s 65 433404, T32982, Hs 352670, Homo sapienε cDNA FU32064 fis, pros, diag
433437, U20536, Hs 3280, caspase 6, apoptosis-related o, fibro, breast cerv, lung, blad, pane, glio, colon, s m
433444, AW975324, Hs 129816, ESTs, pros, diag
433466, AA508353, Hs 105314, relaxin 1 (H1), pros, diag
433485, AI493076, Hs 306098, aldo-keto reductase family 1 , , lung, ε m 70 433495, AW373784, Hε 71, alpha-2-glycoproteιn 1, zinc, breast, proε, diag
433576, BE080715, Hε 161091, ESTε, mela, diag
433662, W07162, Hε 150826, RAB25 RAB25, member RAS oπcoge, colon, diag
433671, AW138797, Hs 132906, 19A24 protein, fibro, mAb
433701, AW445023, Hs 15155, ESTs, test, drag 75 433724, AI827749, Hε 144924, εeππe/threonme protein kiπas, teεt, CTL+s m
433764, AW753676, Hs 39982, zinc finger protein RINZF (NM_, pros, ovaπ drag
433800, AI034361, Hs 135150, lung type-l cell membrane-asso, glio, lung, test, mAb
433914, AF108138, Hs 112160, Homo sapiens DNA helicase homo, test, s m
434011, AW953437, Hs 5486, clone FLB5214, pros, diag 80 434105, AW952124, Hs 13094, presenilms ass∞iated rhomboi, lung, diag
434217, AW014795, Hs 23349, ESTε, angio, diag
434262, AF121858, Hε 12169, sorting nexin 8, mela, CTL+s
434274, AA628539, Hs 57783, ESTs, Moderately similar to AL, test drag 434334, AA912476, Hs 116750, Homo sapiens cDNA FU13221 fis, test, drag 434340, AI193043, Hs 353146, ESTs, Weakly similar to T17226, lung, drag 434360, AW015415 Hs 127780, ESTs, lung drag 434370, AF130988, Hs 58346, ectσdyεplasin 1, anhidrotic re colon, stom, diag 5 434377, AW137148, Hs 306593, intron of penostin (OSF-2os), headnk, drag
434398, AA121098, Hs 3838, εerum- ducible kinase (SNK), angio, breast CTL+s m 434411, AA632649, Hs 201372, ESTs, stom, leuk, drag 434414, AI798376, , gb tr34b07 x1 NCI_CGAP_Ov23 Ho, lung test, colon, drag 434423, NM 006769, Hs 3844, UM domain only 4, pane, drag 10 434449, AW953484, Hs 3849, hypothetical protein FU22041 , sarc, diag
434487, AF143867, Hs 337588, ESTs, Moderately similar to S6, blad, mAb+s m 434596, T59538, , gb yb65g12 s1 Stratagene ovary, angio s
434608, AA805443, Hs 179909, hypothetical protein FLJ22995, test, CTL+s m
434609, R76593, , gb yι60c11 r1 Soares placenta , pros, drag
15 434636, AA083764, Hs 349208, hypothetical protein MGC3178, angio, drag
434649, AA738254, Hs 165390, ESTs, Highly similar to A40350, test, drag
434665, AA642125, Hs 74502, gb nr60e01 s1 NCI_CGAP_Lym3 Ho, pane, diag
434666, AF151103, Hs 112250, T cell receptor gamma locus, pros, mAb+s m 434699, AA643687, Hs 149425, Homo sapiens cDNA FLJ11980 fis, pane, drag
20 434826, AF155661 , Hs 22265, pyruvate dehydrogenase phospha, mela, s m 434846, AW295389, Hs 119768 ESTε, angio, drag 434876, AF160477, Hs 61460, Ig superfamily receptor LNIR lung blad, mAb 434927, H46612, Hs 203815, Homo sapiens HSPC285 mRNA, par, angio, drag n _ 434973, AW449285, Hs 313636, EST, pros, drag
25 435045, BE297155, Hs 143698, ESTs, test, drag
435047, AA454985, Hs 54973, cadhenn like protein VR20, pros mAb 435066, BE261750, Hs 4747, dyskeratosis congemta 1, dysk, colon, CTL+s m 435080, AI831760, Hs 155111, hypothetical protein FU14428, renal, mAb 435094, AI560129, Hs 289008, EST, ovar, cerv, drag 3 O 435099, AC004770, Hs 4756, flap structure-specific endonu, blad, test mela, CTL+s m 435140, AA668123, Hs 134170, ESTs, fibro, diag 435159, AA668879, Hs 116649, ESTs, lung, drag 435206, AI432364, Hs 160594, ESTs test, drag
435243, AW292886, Hs 348932, hypothetical protein dJ434014 , cerv, headnk, drag 35 435292, N20514, Hs 172965, ESTs, mela, drag
435299, AI745458, Hs 343026, ESTs, Weakly similar to T20593, fibro, drag 435479, AF197137, Hs 155101, ATP synthase, H transporting, , pros, ε 435496, AW840171, Hε 265398, PAR 6 beta, breaεt, pane, ovar, drag 435563, AF210317, Hs 95497, solute earner family 2 (fxil, blad, mAb+s m 40 435575, AF213457, Hs 44234, tπggeπng receptor expressed , fibro, mAb+s m 435602, AF217515, Hs 283532, uncharxteπzed bone marrow pπ test drag 435615, Y15065, Hs 4975, potassium voltage-gated channe, glio, mAb 435652, N32388, Hs 334370, uncharxteπzed hypothalamus p, pane, drag 435793, AB037734, Hs 4993, KIAA1313 protein, ovar, lung, uter, drag 45 435849, BE305242, Hs 16098, claudin 2, colon, pane, drag
435876, AW612586, Hs 160271, G protein-coupled receptor 48, pros, mAb 435897, AF269223, Hs 128322, t-complex 11 (a munne top hom, test drag 435904, AF261655, Hs 8910, 1,2-alpha-mannosιdase IC, blad, s m 435918, AF263538, Hs 86232, growth differentiation fxtor , test drag 5 O 435974, U29690, Hs 37744, Homo sapiens beta-1 adrenergic, pros, EWS, mAb+s m 436032, AA150797, Hs 109276, latexin protein, pane, angio, diag 436063, AK000028, Hs 356100, πbosomal protein S24, pros, drag 436120; AI248193, Hs 119860, ESTs, fibro, diag , _ 436199, R38946, Hs 127951, hypothetical protein FU14503, renal, diag 55 436246, AW450963, Hs 119991, ESTs, blad, diag
436251, BE515065, Hs 296585, nucleolar protein (KKE/D repea, colon, test blad, CTL+s m 436278, BE396290, Hs 5097, synaptogyπn 2, pros, mAb 436291, BE568452, Hs 344037, protein regulator of cytokineε, lung, blad, headnk, diag 436293, AI601188, Hε 306201, ESTε, blad, drag 60 436302, AL355841 , Hs 99330, hypothetical protein FLJ23588, lung, drag 436315, BE390513, Hs 27935 hypothetical protein MGC4837, mela, drag 436396, AI683487, Hs 152213, wiπgleεε-type MMTV integration, lung, headnk, proε, pane, diag 436420, AA443966, Hs 31595, ESTs, angio, mAb 436476, AA326108, Hs 33829, bHLH protein DEC2, pane, diag 65 436511, AA721252, Hs 291502, ESTs, lung, drag
436553, AW407157, Hs 181125, immunoglobulin lambda locus, lung, drag 436569, BE439539, Hs 301961, glutathione S-transferase M2 (, blad, s m 436614, AW104388, Hs 149091, ESTs, mela, CTL+s m 436700, AI693690, Hs 301406, hypothetical protein PP3501, mela, mAb 70 436729, BE621807, Hs 351316, transmembrane 4 superfamily me, pane, colon, stom, ovar, lung, blad, mAb 436772, AW975688, Hs 348918, metallothionein 1E (functional, angio, diag 436775, AA731111, Hs 372225, ESTs, uter, ovaπ diag 436839, AA767346, Hs 372277, ESTs, lung, drag 436856, AI469355, Hs 127310, ESTs, mela drag 75 436954, AA740151, Hs 130425, ESTs, fibro, uter, ovaπ diag
436972, AA284679, Hs 25640, claudin 3, ovar, lung, pros, mAb 437052, AA861697, Hs 120591, ESTs, pros, drag
437099, N77793, Hs 48659, ESTs, Highly similar to S14458, test drag
437100, AI761073, Hs 14535, Homo sapiens cDNA FU22314 fi, pane, renal, drag 80 437119, AI379921, Hs 177043, XPJ71387 similarto rhotekin, fibro, diag
437145, AF007216, Hs 5462, solute earner family 4, sodiu, pane, pros, stom, mAb 437156, AI916600, Hs 121194, Homo sapiens cDNA FU21569 fi stom, renal, colon, drag 437181, AI306615, Hs 125343, ESTs, Weakly similarto KIAA07, blad, mAb+s m 437204, AL110216, Hs 355961 , ESTs, Weakly similar to 155214 lung, CTL+s m 437212, AI765021, Hs 210775, ESTs, renal, uter, ovar, diag 437224, AL117628, Hs 97808, ESTs, test, diag 437259, AI377755, Hs 120695, ESTs, lung, drag 437267, AW511443, Hs 258110, ESTs, BPH, diag
437269, AA334384, Hs 149420, ESTs, angio, drag 437330, AL353944 Hs 50115, Homo sapiens mRNA, cDNA DKFZp7, sarc, drag 437381, NM 003684, Hs 5591, MAP kinase interacting senne/, glio, CTL+s 437390, AI125859, Hs 112607, ESTs, lung drag 437412, BE069288, Hs 34744, Homo sapiens mRNA, cDNA DKFZpδ, lung, drag
437435, AA249439, Hs 27027, hypothetical protein DKFZp762H, lung, drag 437437, AA226869, Hs 351623, hypothetical protein DKFZp762L test CTL+s m 437478, AL390172, Hs 317432, branched chain aminotransferas, angio, ε m 437553, AI829935, Hs 130497, ESTs, Weakly similarto MAT8_H, blad, mAb 5 437571 , AA760894, Hs 125350, ESTs, pros, drag
437623, D63880, Hs 5719 chromoεome condensation relate, teεt, drag 437740, AA810265, Hs 122915, ESTs, mela, drag 437802, AI475995, Hs 122910, ESTs, pane, drag
437862, AW978107, Hs 5884, Homo sapiens mRNA, cDNA DKFZp5, mela CTL+s m 0 437908 AI082424, Hs 351043, ESTs, test drag
437915, AI637993, Hs 202312, Homo sapiens clone N11 NTera2D, lung headnk ovar, blad, uter; drag 437931, AI249468, Hs 124434, ESTs, blad, drag
437935, AW939591, Hs 5940, mucin 13, epithelial traπsmemb, colon stom, uter, pane, mAb+s m 437938, AI950087, Hs 369628, gb wq05c02 x1 NCI_CGAP_Kid12 H, renal, ovar, uter, cerv, blad, drag 5 437939, AW298600, Hs 64313, ESTs, Weakly similar to S59501, angio, mAb+s m
437960, AI669586, Hs 369312, ESTs uter, ovar, drag
438167, R28363, Hs 24286, chemokine binding protein 2 (C, ovar, breast, uter, mAb 438199, AW016531, Hs 122147, hypothetical protein FU13189 , breast drag 438209, AL120659, Hs 6111, aryl hydrocarbon receptor nucl, mela, mAb+s m O 438233, W52448, Hε 56147, ESTs, pras, cerv , diag
438274, AI918906, Hε 55080, ESTε, headnk, diag 438403, AA806607, Hs 292206, ESTs, lung, mAb 438438 AA257992 Hs 50651, Janus kinase 1 (a protein tyro, EWS, s m 438450, AI050866, Hs 65853, nodal, mouse, homolog test, drag 5 438456, AA913381, Hs 279763, ESTε, teεt, drag
438552, AJ245820, Hs 6314, type I transmembrane receptor , pros, ovar, diag 438670, AI275803, Hs 123428, ESTs, fibro, CTL+s m 438702, AI879064, Hs 7164, ESTs, lung, drag 438707, L08239, Hs 5326, am o xid syεtem N transporte, ovar, mAb 0 438746, AI885815, Hs 184727, Human melanoma-asεociated and, pane, blad, mela, ovaπ mAb+CTL 438817, AI023799, Hs 163242, ESTs, ovar, uter, blad, renal, drag 438859, AI559626, Hs 93522, Homo sapiens mRNA for KIAA1647, renal, drag 438866, U44385, Hs 6441 , tissue inhibitor of metallopro, mela drag 438873, AI302471, Hs 124292, Homo sapiens cDNA FU23123 fi, fibro, diag 5 438898, AI819863, Hs 106243, ESTs, lung, drag
438915, AA280174, Hs 355711, Williams Beuren syndrome chrom, lung, test, mela, diag 438929, AW195515, Hs 253177, ESTs, renal, diag 438956, W00847, Hs 135056, Human DNA sequence from clone , lung, diag 438966, AW979074, , gb EST391184 MAGE resequences,, renal, drag O 438983, AF085884, Hs 20029, proxroεin binding protein sp3, teεt CTL+s m
438993, AA828995, , gb Od77b08 s1 NCI_CGAP_0v2 Hom, ovar, mAb+ε m 439053, BE244588, Hε 6456, chaperonin containing TCP1, su, test, drag 439092, AA830149, , gb oc44ft)8 s1 NCI CGAP GCB1 Ho, pros, drag 439176, AI446444, Hs 190394, ESTs, Weakly similarto B28096, pros, diag 5 439180, AI393742, Hs 199067, v-erb-b2 avian erythroblastic , breast, ovar, uter, pros, blad, pane, colon, fibre, mela, mAb 439221, AA737106, Hs 32250, ESTs, Moderately similarto 17, EWS, s 439237, AW408158, Hs 318893, ESTs, Weakly similar to A47582, mela, fibro, drag 439239, AI031540, Hs 235331, ESTs, blad, drag
439285, AL133916, Hs 47860, hypothetical protein FLJ20093, lung, breast diag 0 439310, AF086120, Hs 102793, ESTs, mela, drag
439318, AW837046, Hs 6527, G protein-coupled receptor 56, colon, breast, ovar, uter, cerv, pros, lung, headnk, blad, mela, mAb+s m 439335, AA742697, Hs 62492, NM_052863 Homo sapiens secreto, fibro, uteπ diag 439366, AF100143, Hs 6540, fibrobiast growth fxtor 13, pros, CTL+s m 439382, BE247684, Hs 103070, ESTs, angio, diag 5 439394, AA149250, Hs 56105, ESTs, lung, drag 439410, AA632012, Hs 188746, ESTs, angio, diag
439453, BE264974, Hs 6566, thyroid hormone receptor inter; lung, esoph, ovaπ mAb+s m 439496, BE616501, Hs 32343, Homo sapiens, Similar to RIKEN, mela, esoph, diag 439659, AW970780, Hs 59483, leucine-πch repeat-containing, ovar, stom, mela, colon, mAb 0 439668, AI091277, Hs 302634, frizzled (Drasophila) homolog , ovar, uter, mAb
439670, AF088076, Hs 59507, ESTs, Weakly similar to AC0048, lung, headnk, cerv, drag 439702, AW085525, Hs 55964, ESTs, mela, drag
439706, AW872527, Hs 59761, ESTs, Weakly similarto DAP1_H, ovar, lung, headnk, diag 439735, A1635386, Hs 142846, hypothetical protein, pros, drag 5 439737, AI751438, Hs 41271, Homo sapiens mRNA full length , pane, drag
439750, AL359053, Hs 57664, Homo sapiens mRNA full length , pane, fibro, breast, drag 439755, AW748482, Hs 77873, B7 homolog 3, sarc, mAb
439759, AL359055, Hs 67709, Homo sapiens mRNA full length , colon, stom, pane, leuk, lung, diag 439778, AL109729, Hs 99364, putative transmembrane protein, pros, mAb+s m 0 439780, AL109688, , gb Homo sapiens mRNA full leng, blad, esoph, drag
439820, AL360204, Hs 283853, Homo sapiens mRNA full length , ovar, uter, cerv, breast pros , drag 439864, AI720078, Hs 291997, ESTs, Weakly similarto A47582, test, diag 439867, AA847510, Hs 161292, ESTs, pane, diag 439920, H05430, Hs 288433, neurotπmin, pane, mAb+diag 439926, AW014875 Hs 137007, ESTs, blad, esoph, lung, cerv, drag 439963, AW247529, Hs 6793, platelet-activating fxtor xe, breast, lung, blad, s 440042, AI073387, Hs 133898, ESTs, ovar, CTL+s m 5 440086, NM 005402, Hs 6906, v-ral simian leukemia viral on, angio, drag
440099, AUJ80058, Hs 6909, DKFZP564G202 protein, pane, drag 440119, AA865455, Hs 125331 , ESTs, Moderately similar to un, test, diag 440138 AB033023, Hs 318127, hypothetical protein FLJ10201, lung, CTL+s m 440151, AA868167, , gb ak38e07 s1 SoaresJestisJJH, sarc, diag 0 440207, AI371978, Hs 128326, ESTs, test, diag
440209, H05049, Hs 247837, neurexin 3, fibro, diag
440210, AW674562, Hs 122128, ESTs, glio, diag
440225, BE295782, Hs 159, tumor necrosis fxtor receptor, glio, mAb 440238, AW451970 Hs 155644, paired box gene 2, ovar, drag 15 440260, AI972867, Hs 7130, copme IV, pros, drag
440273, AI805392, Hs 325335 Homo sapiens cDNA FLJ23523 fi, lung, fibro, diag
440274, R24595, Hs 7122, scrapie responsive protein 1, sarc, diag 440311, AI733079, Hs 125407, ESTs, Moderately similar to AL, renal, drag 440325, NM-003812, Hs 7164, a disintegnn and metaltoprote, lung, mAb 0 440333, AI378424, Hs 288761, hypothetical protein FU21749, pros, CTL+s m
440449, AA885430, Hs 201925, Homo sapiens cDNA FLJ13446 fis, breast drag 440452, AI925136, Hs 55150, ESTs, Weakly similar to CAYP_H, fibro, drag 440457, BE387593, Hs 21321, Homo sapiens clone FLB9213 PRO, mela, drag _ _ 440484, BE328156, Hs 150356, ESTs, pane, diag
25 440529, AW207640, Hs 16478, Homo sapiens cDNA FU21718 fi, pros, diag
440659, AF134160, Hs 7327, claudin 1, lung, mAb 440704, M69241, Hε 162, inεulm-like growth fxtor bin, lung, glio, ovar, drag 440773, AA352702, Hs 37747, Homo sapiens, Similar to RIKEN, test, diag 440801 , AA906366, Hs 370038, ESTs, pros, drag 30 440819, AI809444, Hs 202108, ESTs, pros, drag
440901, AA909358, Hs 128612, ESTs, ovar, pros, drag 440943, AW082298, Hs 146161, hypothetical protein MGC2408, lung drag 440983, M20681, Hs 7594, εolute camerfamily 2 (fxil, test, mAb 441020, W79283, Hs 35962, ESTs, lung, pane, diag 35 441031, AI110684, Hs 7645, fibππogen, B beta polypeptide, lung, pane, colon, CTL+ε m
441085, AW136551, Hs 181245, Homo sapiens cDNA FU12532 fis, pane, ovar, stom, uter, lung diag 441134, W29092, Hs 346950, cellular retinoic acid binding, εarc, diag 441247, AW118681, Hs 128051, Homo sapiens thymic stromal ly, pros, diag 441321, H17182, Hs 7771, B-cell associated protein, test, drag 40 441345, AW068579, Hs 7780, Homo sapienε mRNA, cDNA DKFZpδ, pros, drag
441350, AB020690, Hs 7782, paraneoplastie antigen MA2, pane, mAb+CTL 441377, BE218239, Hs 202656, ESTs, uter, endo, lung, diag 441384, AA447849, Hs 288660, retinoic id induced 3, ovaπ mAb+s m 441392, AW451831, Hs 222119, ESTs, Weakly similarto S30433, renal, drag 45 441457, AW996651, Hs 43838, ESTs, angio, diag 441495, AW294603, Hs 127039, ESTs, blad, diag 441525, AW241867, Hs 127728, ESTs, lung, diag 441553, AA281219, Hs 121296, ESTs, lung, test ovaπ CTL+s m
441633, AW958544, Hε 112242, normal mucosa of eεophaguε spe, blad, lung, cerv, headnk, colon, pane, ι 50 441790, AW294909, Hs 132208, ESTs, lung, diag 441801, AW242799, Hs 86366, ESTs, blad, drag 441835, AB036432, Hs 184, advanced glycosylation end pro, fibro, mAb 441859, AW194364, Hs 380444, ιnterteukιn-4 induced gene-1 p, ovar, mela, fibro, mAb _ 441878, AI801869, Hs 127982, ESTs, test, diag
55 442006, AW975183, Hs 372210, ESTs, Weakly similar to S72482, fibro, angio, CTL+s m 442082, R41823, Hs 7413, calsynteπιn-2, breast proε, ovaπ drag 442104, L20971, Hs 188, phosphodieεteraεe 4B, cAMP-εpe, angio, CTL+s m 442108, AW452649, Hs 343259, ESTs, lung, diag 442242, AV647908, Hs 90424, Homo sapiens cDNA FU23285 fi, BPH, diag 60 442323, AW016669, Hs 29190, ESTs, breaεt, diag 442333, AI650877, Hε 129302, ESTs, test, diag
442432, BE093589, Hs 38178, hypothetical protein FU23468, blad, lung, pane, esoph, mela, CTL+s m 442438, AA995998, Hs 370007, gb oε26b03 ε1 NCI CGAP_Kιd5 Ho, uter, ovar, renal, drag 442441, AI820662, Hs 129598, ESTs, breast, diag 65 442503, AF147078, Hs 375031, p53-responsιve gene 5, mela, drag 442506, BE566411, Hs 41726, ESTs, angio, drag
442573, H93366, Hs 7567, branched chain aminotransferas, ovar, pane, angio, test, s m 442577, AA292998, Hε 163900, ESTε, blad, pane, colon, stom, ovaπ drag 442580, AI733682, Hs 130239, ESTs, breast , diag 70 442609, AL020996, Hs 8518, selenoproteiπ N, mela, drag
442613, AI004002, Hs 130522, Kv channel-interacting protein, glio, diag 442622, NMJ00435, Hs 8546, Notch (Drasophila) homolog 3, ovaπ mAb 442711, AF151073, Hs 8645, hypothetical protein, angio, mela, εarc, diag 442739, NM_007274, Hs 8679, cytosolic xyl coenzyme A thio, mela, s m 75 442757, AI739528, Hs 28345, ESTs, mela, diag
442818, AK001741, Hs 8739, hypothetical protein FU10879, breast, drag 442821, BE391929, Hs 8752, transmembrane protein 4, ovar, diag 442832, AW206560, Hs 253569, ESTs, pros, fibro, drag 442896, R37725, Hs 283093, ESTs, pane, drag 80 442994, AI026718, Hs 16954, ESTs, blad, fibro, drag
443054, AI745185, Hs 84520, yes-associated protein 65 kDa, blad, diag 443162, T49951, Hs 9029, DKFZP434G032 protein, blad, lung, CTL+s m 443171, BE281128, Hs 9030, TONDU, blad, ovaπ diag 443184, AI638728 Hs 135159, ESTs, sarc, drag
443211, AI128388, Hs 143655, ESTε, blad, ovar, lung, headnk, stom, colon, drag 443216, W80487, Hs 324521, hypothetical protein DC50, test, diag 443257, AI334040, Hs 11614, HSPC065 protein, fibro, CTL+s m 443400, R28424 Hs 250648, ESTs, lung, diag
443523, AK001575, Hε 9536, hypothetical protein FLJ10713, teεt, CTL+s m 443537, D13305, Hε 203, chotecystokinin B rxeptoπ test, mAb 443648, AI085377, Hs 143610, ESTs, lung headnk, diag 443709, AI082692, Hs 134662, ESTs, fibro, drag 443715, AI583187, Hs 9700, cyclin E1, lung, stom, ovar, colon, CTL+s m
443785, AW449952, Hs 190125, basic-helix-loop-helix PAS pro, glio, uter, ovaπ CTL+s m 443802, AW504924, Hs 9805, KIAA1291 protein, sara drag 443883, AA114212, Hs 9930, senne (or cysteine) pratemas, sarc, s m 443885, H91806, Hε 15284, ESTε, mela, drag 443892, AI889572, Hs 246875, ESTs, lung, drag
443950, NM_001425, Hs 9999, epithelial membrane protein 3, mela, mAb 443968, AA287702, Hs 10031, KIAA0955 protein, angio, drag 443983, H04482, Hs 163724, ESTs, mela, mAb
443991, NM 002250, Hs 10082, potassium intermediate/small c, proε, colon, uteπ mAb 444009, AI380792, Hs 135104, ESTs, angio, diag
444151, AW972917, Hs 128749, alpha-methylacyl CoA rxemase, pros, mAb 444159, AF116846, Hs 10431, dead πnger (Drasophιla)-lιke , test, CTL+s m 444163, AI126098, , FGENESH predicted RNaseH domai, blad, s m 444301, AK000136, Hs 10760, aspoπn (LRRclaεs 1), pane, drag 444325, AW152618, Hs 16757, ESTs, esoph, drag
444330, AI597655, Hs 49265, ESTs, angio, drag
444342, NM_014398, Hs 10887, similar to lysosome-associated, hepC, lung, fibro, blad, esoph, diag 444378, R41339, Hs 47860, neurotrophic tyrosine kinase, , lung, glio, mAb+s m 444409, AI792140, Hs 49265, ESTs, angio, drag 444444, AI149332, Hs 14855, ESTs, blad, drag
444471, AB020684, Hs 11217, KIAA0877 protein, glio, lung, colon , mAb 444476, AF020038 Hs 11223, isocitrate dehydrogenase 1 (NA blad, ε m 444484, AK002126 Hs 11260, hypothetical protein FLJ11264, pros, drag
444633, AF111713, Hs 12284, junctioπal adhesion motecule 1, ovar, uter, breaεt, cerv, blad, headnk mAb 444649, AW207523, Hs 371001, ESTs, blad, diag
444670, H58373, Hs 332938, hypothetical protein MGC5370, εarc, drag
444754, T83911 , Hs 11881 , transmembrane 4 superfamily me, pane, omuc, stom, lung, colon, mAb+s m 444809, BE207568, Hs 208219, oculospaπin, mela, mAb 444823, BE262989, Hs 12045, putative protein, test, diag 444863, AW384082, Hs 104879, seπne (or cysteine) protemas, mela, s 444895, AI674383, Hs 22891 , solute earner family 7 (catio, ovaπ mAb+s m 444995, AJ272265, Hs 12230, secreted phosphoprotem 2, 24k, hepC, pane, drag 445019, AI205540, Hs 281295, ESTs, headnk, lung, colon, drag 445070, NM 000677, Hs 258, adeπosiπe A3 receptor, glio, renal, mAb 445076, AI206888, Hs 154131, ESTs, test, diag
445084, H38914, Hs 250848, hypothetical protein FLJ14761, sarc, mAb 445093, AI207197, Hs 156905, ESTs, test, diag 445109, AF039916 Hs 12330, xtonucleoside tnphosphate di, pros, s m 445119, AF035121, Hs 12337, kinase insert domain receptor , angio, mAb 445160, AI299144, Hs 101937, sine oculis homeobox (Drosophi, sarc, CTL+s 445182, AW189787, Hs 361778, ESTs, blad, diag 445247, AW274290, Hs 153997, ESTs, mela, diag 445279, R41900, Hs 22245, ESTs, angio, diag 445363, NM_005993, Hs 12570, tubulin spxifio chaperone d, teεt drag 445413, AA151342, Hε 12677, CGI-147 protein, pros, colon, uter, ovar, lung, pane , diag 445418, AW139377, Hs 127179, cryptic gene, pane, diag 445424, AB028945, Hs 12696, cortxtin SH3 domain-binding p, pros , drag 445443, AV653838, Hs 295131, ESTε, lung, drag 445654, X91247, Hε 13046, thioredoxin reductase 1, lung, s 445684, AK001696, Hs 13109, Ran binding protein 11, angio, drag
445701, AF055581, Hs 13131, lymphocyte adaptor protein, angio, CTL+s m 445784, AI253155, Hs 146065, ESTs, mela, CTL+s 445885, AI734009, Hs 127699, KIAA1603 protein, pros, fibro, drag 445900, AF070526, Hs 125036, Homo sapiens clone 24787 mRNA , renal, leuk, mAb 445911, AI985987, Hs 145645, ESTs, Moderately similar to AL, blad, diag 445982, BE410233, Hs 13501, pescadillo (zebrafish) homolog, mela, diag 446057, AI420227, Hs 366053, Trp-p8 transient receptor potβ, pros, mAb 446082, AI274139, Hs 156452, ESTs, blad, diag 446098, AW072215, Hs 208470, ESTs, angio, diag 446100, AW967109, Hs 13804, hypothetical protein dJ462023 , pros, diag 446102, AW168067, Hs 317694, ESTs, lung, diag
446113, AW967553, Hs 323518, Homo sapiens mRNA for FU00083, test mAb 446269, AW263155, Hs 14559, hypothetical protein FU10540, lung, headnk, CTL+s m 446291 , BE397753, Hs 14623, interferon, gamma-mducible pπ mela, diag 446292, AF081497, Hs 279682, Rh type C glycoprotein, lung, cerv, mAb
446293, AI420213, Hs 149722, LIM domain transcnption fxto, ovar, test, drag 446320, AF126245, Hs 14791, xyl-Coenzyme A dehydrogenase , pros, s m 446332, AK001635, Hs 14838 hypothetical protein FLJ10773, breast, drag 446342, BE298665, Hs 14846, solute earner family 7 (catio, uter, colon, pros, mela, mAb 446428, AW082270, Hs 12496, ESTs, Weakly similar to ALU4_H, fibro, diag
446528, AU076640, Hs 15243, nucleolar protein 1 (120kD), lung, test, diag 446608, N75217, Hs 175622, ESTs, uter, fibro, diag 446626, AW292180, Hs 156142, ESTs, pros, diag 446636, AC002563, Hs 15767, citron (rho-iπteractmg, seππ, lung, CTL+s m
446644, NM_003272, Hs 21065, transmembrane 7 superfamily me, mela, mAb
446673, NM 016361, Hs 15871 , LPAP for lysophosphatidic id, blad, diag
446727, AB011095, Hs 16032, KIAA0523 protein, angio, CTL+s m 446733, AA863360, Hs 26040, ESTs, Weakly similar to fatty , breast, s m
446755, AW451473, Hε 16134, seπne/threonine kinase 10, mela CTL+s m
446791, AI632278, Hs 195922, ESTs, test diag
446839, BE091926, Hs 16244, mitotic spindle coiled-coil re, test, drag
446856, AI814373, Hs 164175 ESTs, lung, drag 446868, AV660737, Hs 348297, ESTs, pane, drag
446872, X97058, Hs 16362, pyπmidinergic receptor P2Y, G, lung, mAb
446932, AA961459, Hs 125644, ESTs, fibro, drag
446967, AI699629, Hs 156781, ESTε, fibro, drag
446979, AI654443, Hs 197683, ESTs, test, diag 446984, AB020722, Hs 16714, Rho guanine exchange fxtor (G, angio, CTL+ε m
446989, AK001898, Hs 16740, hypothetical protein FLJ11036, lung, headnk, diag
446998, N99013, Hs 278966, Homo sapiens mRNA, cDNA DKFZpδ, pane, fibro, drag
446999, AA151520 Hs 351416, hypothetical protein MGC4485, headnk, diag 447004, AW296968, Hs 157539, FGENESH predicted s∞reted pro, glio, drag 447078, AW885727, Hs 9914, ESTs, lung, diag
447126, AW150632, Hs 170307, Ral guanine nucleotide exchang, angio diag
447164, AF026941, Hs 17518, vipiπn similarto mflammat, colon, lung, breast, stom, hepC, esoph, mela, drag 447178, AW594641, Hs 192417, ESTs, mela, drag 447188, H65423, Hs 17631, hypothetical protein DKFZp434E, test, drag 447210, AF035269, Hs 17752, phosphatidylsenne-specific ph, pros, mela, s m
447289, AW247017, Hε 36978, melanoma antigen, family A, 3, lung, mela mAb+CTL
447334, AA515032, Hε 91109, ESTs, blad, drag
447343, AA256641 , Hs 236894, ESTs, Highly similar to S02392, lung, blad, pane, headnk mela, mAb+s m
447350, AI375572, Hs 172634, v-erb-a avian erythroblastic I, breast, ovar, uter, drag 447377, X77343, Hε 334334, tranεcπptioπ factor AP-2 alph, breast, lung, mela, CTL+s m
447395, AI418412, Hs 184793, Homo sapiens cDNA FU21880fi, pane, drag
447437, U07225, Hs 339, puπnergic receptor P2Y, G-pro, blad, mAb
447499 AW262580, Hs 147674, protocadhenn beta 16, pros, glio, ovar , mAb+s m
447532, AK000614, Hs 18791, hypothetical protein FLJ20607, lung, blad, CTL+ε m 447534, AW953935, Hs 288655, ESTs, lung, test, diag
447578, AA912347, Hs 136585, ESTs, Weakly similar to JC5314, ovar, s m
447595, AW379130, Hs 18953, phoεphodiesterase 9A, pros, CTL+s m
447604, AW089933, Hs 301342, hypothetical protein MGC4342, mela, diag
447636, Y10043, Hs 19114, high-mobility group (πoπhiston, lung CTL+s m 447733, AF157482, Hs 19400, MAD2 (mitotic arrest deficient, test, drag
447749, T53260, Hs 8297, ESTs, renal, drag
447761, AF061573, Hs 19492, protocadhenn 8, EWS, glio, mAb
447768, X86400, Hs 19520, FXYD domain-containing ion tra, renal, mAb
447818, W79940, Hs 355279, Homo sapienε clone 24670 mRNA , renal, drag 447835, AW591623, Hs 164129, ESTs, Weakly similar to I38022, renal, ovar, uteπ drag
447881, BE620886, Hs 355279, GCN1 (general control of ammo, renal, diag
447937, AL109716, Hs 20034, Homo sapiens mRNA full length , mela, mAb
447993, AW139525, Hs 170362, ESTs, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m
448030, N30714, Hs 325960, membrane-spanning 4-domaιns, ε, pane, leuk, renal, stom lung, mAb 448045, AJ297436, Hε 20166, proεtate stem cell antigen, blad, pane, pros, mAb
448105, AW591433, Hs 298241, Transmembrane protease, seπne, breast, pane, colon, lung, ovar, stom, mAb+diag+s m
448133, AA723157, Hs 73769, folate receptor 1 (adult), ovar, fibro, mAb
448140, AF146761, Hs 20450, BCM like membrane protein prec, fibro, mela leuk, mAb
448153, Y10805, Hs 20521, HMT1 (hπRNP methyltransferase,, test, CTL+s m 448181, AF272833, Hs 279763, hypothetical protein FU10504, test drag
448204, AI475124, Hs 170561, ESTs, sarc, diag
448231, AI701916, Hs 202509, ESTs, angio, diag
448258, BE386983, Hs 343214, hypothetical protein FU20396, mela, ovaπ mAb
448262, AW880830, Hs 186273, ESTs, blad, diag 448275, BE514434, Hs 20830, kinesin-like 2, ovar, esoph, mela, drag
448278, W07369, Hs 11782, ESTs, lung, diag
448290, AK002107, Hs 20843, Homo sapiens cDNA FU11245 fis, pros, diag
448321, NM_005883, Hs 20912, adenomatous polyposis coli Ilk, glio, CTL+s m
448357, N20169, Hs 108923, RAB38, member RAS oncogene fam, lung, mela, diag 448410, AK000227, Hs 21126, hypothetical protein FU20220, mela, diag
448437, AW470125, Hs 220529, gb xw60c04 x1 NCI_CGAP_Pan1 Ho, pane, colon, drag
448499, BE613280, Hs 77550, p53-regulated DDA3, glio, diag
448569, BE382657, Hs 21486, signal transducer and xtivato, pane, headnk, fibro, cerv, mela, renal, CTL+s m
448588, AI970276, Hs 156905, KIAA1676, test, CTL+s m 448595, AB014544, Hs 21572, KIAA0644 gene product, breast glio, mAb
448664, AI879317, Hs 334691, splicing fxtor 3a, subunit 1 „ mela, CTL+s m
448674, W31178, Hs 154140, ovary-spxific idic protein, angio, diag
448692, AW013907, Hs 167531, methylcrotonoyl Coenzyme Acaπ pros, pros, s m
448706, AW291095, Hs 21814, interleukin 20 receptor, alpha pros, uter, blad, colon, mAb 448719, AA033627, Hs 21858, tnnucleotide repeat containm, mela, sarc, CTL+diag
448775, AB025237, Hs 388, nudix (nucleoside diphosphate , test drag
448811, AI590371, Hs 199460, ESTs, esoph, pane, mAb
448939, BE267795, Hs 22595, hypothetical protein FU10637, test, CTL+s m
448966, AW372914, Hs 86149, phoεphoinoεitol 3-phosphate-bι, mela, CTL+s m 448981, AI968719, Hs 195387, ESTε, teεt, diag
448988, Y09763, Hs 22785, gamma aminobutyric xid (GABA), pros, cerv, colon, lung, stom, blad, headnk, ovar, breast mAb
448993, AI471630, Hs 355952, KIAA0144 gene product, lung, blad, drag
448999, AF179274, Hs 22791, transmembrane protein with EGF, pros, glio , mAb 449003, X76342, Hs 389, alcohol dehydrogenase 7 (class, lung, headnk, s m 449019, AI949095, Hs 67776, ESTs, Weakly similar to T22341 , blad, lung, drag 449027, AJ271216, Hs 22880, dipeptidylpeptidaεe III, blad, colon, ovaπ ε m 449040, NM 012191, Hε 22919, putative tumor suppressoπ lung, CTL+s m 449078 AK001256, Hs 22975, KIAA1576 protein, mela, diag
449101, AA205847, Hs 23016, G protein coupled receptoπ lung headnk, mAb 449109. AW270992, Hs 120949, ESTs, Weakly similar to ALU7_H, εarc, drag 449156, AF103907, Hs 171353, prostate cancer antigen 3, non, pros, mAb+CTL 449207, AL044222, Hs 23255, nucleopoπn 155kD, lung, drag 449228, AJ403107, Hs 148590, protein related with psonasiε, lung, diag
449230, BE613348, Hs 356392, melanoma cell adhesion molecul, lung, cerv, headnk, blad, ovar, colon, mAb 449317, AW293413, Hs 132906, 19A24 protein, mela, mAb
449318 AW236021, Hs 78531, Homo sapiens, Similarto RIKEN, headnk, lung, angio, CTL+s m 449322, AI638616, Hs 196566, ESTs, test, drag 449338, H73444, Hs 394, adreπomedullm renal, drag
Ψ19394, AA004368, Hs 18160, Homo sapiens cDNA FLJ11550 fis, angio, mAb 449437, AI702038, Hs 100057, Homo sapienε cDNA FLJ22902 fi, test, drag 449448, D60730, Hε 57471, ESTε, blad, lung, headnk, breaεt, drag 449467, AW205006, Hs 197042, ESTs, lung, diag 449494, AW237014, Hs 315369, aquapoπn 4, fibro, diag
449569, AI656634, Hs 195389 ESTs, test, drag 449592 AI655494, Hs 195718, ESTs pane, drag 449618, AI076459, Hs 15978, KIAA1272 protein, angio, diag 449625, NM_014253, Hs 349094, odz (odd Oz ten m, Drasophila), pros, drag 449650, AF055575, Hs 23838, calcium channel, voltage-depen, pros, mAb
449680, AI033821, Hs 12160, ESTs, renal, drag 449961, AW265634, Hs 133100, ESTs, glio, esoph, lung, blad , diag 449976, H06350, Hs 135056, Human DNA sequence from clone , lung, diag 450096, AI682088, Hs 79375, single-minded (Drasophila) hom, pras, CTL 450098, W27249, Hs 8109, hypothetical protein FLJ21080, breast, lung, stom uteπ diag
450149, AW969781, Hs 132863, Zio family member 2 (odd paire, εarc, CTL+s m 450152, AI138635, Hs 22968, intron ofVEGFR, renal, drag 450377, AB033091, Hε 355925, KIAA1265 protein, ovar, colon, drag 450382, AA397658, Hs 60257, Homo sapiens cDNA FLJ13598 fis, pros, diag 450400, AI694722, Hs 279744, ESTs, pane, drag
450431 , AW136797, Hs 266041 , ESTs, test, diag 450451 , AW591528, Hs 202072, ESTs, uter, endo, diag 450506, NM_004460, Hs 418, fibroblast tivation protein,, pane, esoph, diag 450534, AI570189, Hs 25132, KIAA0470 gene product, angio, CTL+s m 450581, AF081513, Hs 25195, TGF-beta 4, uter, cerv, test, diag
450635, AW403954, Hs 25237, mesenchymal stem cell protein , blad, mAb 450642, R39773, Hs 7130, cop e IV, pros, diag 450656, AA010539, Hs 18912, unnamed protein product, fibro, uteπ CTL+s m 450663, H43540, Hs 25292, πbonuclease HI, large subunit, mela, s m 450676, AI147155, Hε 279727, ESTs, sarc, drag
450684, AA872605, Hs 25333, interleukin 1 receptor, type I, blad, lung, headnk, mAb 450690, AA296696, Hs 333418, FXYD domain-containing ion tra, mela, drag 450693, AW450461, Hs 203965, ESTs, pros, uteπ diag 450719, AI096837, Hs 21349, ESTs, Weakly similar to RB8B_H, test, diag 450737, AW007152, Hs 63325, transmembrane protease, seπne, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m 450785, AA852713, Hε 108885, Homo εapienε, alpha-1 (VI) col, sara, CTL+s m 450832, AW970602, Hs 105421, ESTs, lung, diag
451027, AW519204, Hs 40808, Homo sapiens, Similar to RIKEN, pros, uter, glio, drag 451035, AU076785, Hs 430, plastin 1 (I isoform), pane, diag 451050, AW937420, Hs 351869, ESTs, mela, diag
451099, R52795, Hs 25954, interteukin 13 receptor, alpha, glio, fibro, mela, mAb 451106, BE382701, Hs 25960, N-MYC oncogene, test, ovaπ CTL+s 451110, AI955040, Hs 265398, PAR-6 beta (partitioning def, breast, ovar, lung, colon, CTL+s 451181, AI796330, Hs 207461, ESTs, pane, drag 451253, H48299, Hs 26126, claudin 10, lung, ovar, pane, mAb 451291, R39288, Hs 6702, ESTs, lung, diag 451295, AI557212, Hs 17132, ESTs, Moderately similar to 15, pane, diag 451320, AW118072, Hs 350251, dixylglycerol kinase, zeta (1, lung, s m 451346, NM_006338, Hs 26312, glioma amplified on chromosome, ovar, mAb 451386, AB029006, Hs 26334, spastic paraplegia 4 (autosoma, lung, drag 451398, AI793124, Hs 144479, ESTs, breast, ovaπ diag 451411, AA017492, Hs 135655, EST, pros, drag
451497, H83294, Hs 284122, Wnt inhibitory fxtor-1, uter, fibro, pros, colon, sarc, diag 451541, BE279383, Hs 26557, plakophilin 3, lung, blad, ovaπ drag 451592, A1805416, Hs 213897, ESTs, lung, headnk, diag
451635, AA018899, Hs 127179, cryptic gene, pane, diag 451663, AI872360, Hs 209293, ESTs, pros, drag 451720, AW970985, Hs 290853, ESTs, pros, diag 451743, AW074266, Hs 336428, ESTs, lung, diag 451820, AW058357, Hs 199248, ESTs, pane, mAb
451844, T61430, , gb yc06a03 s1 Stratagene lung , blad, drag 451982 F13036, Hs 27373, Homo sapiens mRNA, cDNA DKFZpδ, pros, blad, mAb 451999, AW176401, Hs 380623, DEAD/H (Asp-Glu Ala-Asp/His) b, teεt, CTL+s m 452046, AB018345, Hs 27657, KIAA0802 protein, lung, uteπ CTL+s m 452208, AA024792, Hs 31895, hypothetical protein MGC4093, renal, diag
452240, AI591147, Hε 61232, ESTε, blad, lung, headnk, pane, cerv, drag
452243, AL355715, Hs 28555, programmed cell death 9 (PDCD9, breast drag
452244, N33530, Hs 176674, ESTs, mela, drag 452291, AF015592, Hs 28853, CDC7 (cell division cycle 7, S, test, CTL+s m
452295, BE379936, Hs 28866, programmed cell death 10, lung, diag
452298, AI039243 Hs 278585, ESTs, angio, diag
452304, AA025386, Hs 61311, ESTs, Weakly similarto S10590, lung, pane, blad, stom, esoph, fibro.colon s m 452316, AA298484, Hs 61265, ESTs, Moderately similar to G7, blad, diag
452340, NM_002202 Hs 505, ISL1 transcription factor, UM, pane, pras, CTL+s m
452353, C18825, Hs 29191, epithelial membrane protein 2, pros, breaεt, mAb
452355, N54926, Hs 29202, G protein-coupled receptor 34, glio, fibro, pane, mAb
452367, U71207, Hs 29279, eyes absent (Drasophila) homol, lung, pros, ovar, uteπ CTL+s m 452416, AA026115, Hs 114777, ESTs, fibro, diag
452461, N78223, Hs 108106, transcnption fxtoπ blad, lung, headnk, ovar, glio, stom, colon, cerv, CTL+s m
452571, W31518, Hs 34665, ESTs, stom, lung, pane, colon, fibro, drag
452594, AU076405, Hs 29981, solute camerfamily 26 (sulf, ovaπ mAb
452613, AA461599, Hs 23459, ESTε, lung, drag 452679, Z42387, Hs 83883, transmembrane, prostate androg, pros, colon, pane, pros, mAb
452705, H49805, Hs 246005, ESTs, pane, drag
452717, AW160399, Hs 30376, hypothetical protein, pros, drag
452721, AJ269529, Hε 301871, εolute camerfamily 37 (glyc, pros, mAb
452732, BE300078, Hs 80449, Homo sapiens, clone IMAGE 3535, blad, drag 452744, AI267652 Hs 246107, Homo sapiens mRNA, cDNA DKFZp4, mela, drag
452792, AB037765, Hs 30652, KIAA1344 protein, pros, uter, breaεt , drag
452795, AW392555, Hs 18878, hypothetical protein FLJ21620, renal, headnk, colon, lung, pane, CTL
452796, AB011100, Hs 30656, KIAA0528 gene product, test, diag 452833, BE559681, Hs 30736, KIAA0124 protein, lung, mela, CTL+s m 452865, AI924046, Hs 119567, ESTs, Weakly similar to A47582, lung, drag
452899, M96739, Hs 30956, nescient helix loop helix 1, sarc, CTL+s m 452924, AW580939, Hs 97199, complement component C1q recep, angio, drag
452933, AW391423, Hs 288555, Homo εapiens cDNA FLJ22425 fi, angio, CTL+s m
452934, AA581322, Hs 4213, hypothetical protein MGC16207, lung, blad, drag 452955, AW390282, Hs 31130, transmembrane 7 superfamily me, pros, mAb+s m
453006, AI362575, Hs 303171, ESTε, proε, drag
453028, AB006532, Hs 31442, RecQ protein like 4, blad, lung test, CTL+s m
453085, AW954243, Hs 351573, KIAA0251 protein, angio, drag
453096, AW294631, Hs 351270, ESTs, pros, diag 453102, NMJ07197, Hs 31664, fπzzled (Drasophila) homolog , lung, headnk, colon, mAb
453107, NM_016113, Hs 279746, vamlloid receptor-like protei, mela, mAb
453134, AA032211, Hs 118493, ESTs, blad, drag
453142, AA033648, Hs 7473, Homo sapiens gap junction prot fibro, mAb
453160, AI263307, Hs 356901 , H2B histone family, member L, lung, pane, pras, drag 453210, AL133161, Hs 32360, hypothetical protein FU10867, lung, CTL+s m
453216, AL137566, Hs 32405, progeεterone receptor (PR), blad, mAb+s m
453256, AI565587, Hs 32556, KIAA0379 protein, mela, drag
453310, X70697, Hs 553, solute earner family 6 (neuro, fibro, mAb
453321, AI984381, Hs 232521, ESTs, blad, drag 453323, AF034102, Hs 32951 , εolute earner family 29 (nucl, ovar, CTL+s m
453331, AI240665, Hs 352537, ESTs, breast, lung, pane, esoph, mAb+diag+s
453344, BE349075, Hs 44571, ESTs, mela, drag
453348, BE272318, Hs 8595, hypothetical protein FU12438, teεt, CTL+ε m
453365, AA035211, Hs 17404, SOX7 SRY (sex determining regi, angio, blad, CTL+s m 453370, AI470523, Hs 139336, ATP-binding cassette, sub-fami, pros, mAb
453389, BE273648, Hs 32963, cadhenn 6, type 2, K-cadhenn, renal, ovar, blad, mAb+ε m
453392, U23752, Hs 32964, SRY (sex determining region Y), ovar, lung, glio, sara, CTL+s m
453459, BE047032, Hs 257789, ESTε, ovar, cerv, blad, uter, pane, angio, lung, drag
453464, AI884911, Hs 32989, receptor (caloitonin) activity, pros, mAb 453633, AA357001, Hε 34045, hypothetical protein FU20764, lung, eεoph, teεt, drag
453637, NM 002589, Hε 34073, BH-protocadheπn (brain-heart), headnk, mAb
453642, AI370936, Hs 34074, dipeptidylpeptidase VI, glio, mAb
453779, N35187, Hs 43388, 28kD interferon reεponεive pro, mela, drag
453789, AA628517, Hε 118502, ESTs, angio, diag 453857, AL080235, Hs 35861, Ras induced senescence 1 (RIS1, glio, lung, uter, headnk, cerv, pane, pros, εara, mAb
453883, AI638516, Hs 347524, cofxtor required for Sp1 tran, blad, lung, drag
453884, AA355925, Hs 36232, KIAA0186 gene product, lung, ovar, test, esoph, drag 453912, AL121031, Hε 356843, SWI/SNF related, matnx associ, mela, drag
453922, AF053306, Hs 36708, budding uninhibited by beπzimi, colon, stom, lung, test, CTL+s m 453935, AI633770, Hs 42572, ESTs, pane, diag
453941, U39817, Hs 36820, Bloom syndrome, lung, cerv, headnk, CTL+s m
453964, AI961486, Hs 249196, ESTs, lung, drag
453966, BE148734, Hs 63325, transmembrane protease, senne, colon, blad, lung, ovar, pane, headnk, mAb+diag+s m
453985, N44545, Hs 251865, ESTs, test, diag 454034, NMJ00691 , Hs 575, aldehyde dehydrogenase 3 famil, lung, headnk, s m
454042, H22570, Hs 47860, hypothetical protein FU20093, lung, drag
454066, X00356, Hs 37058, calcitonin/calcitonm related , lung, drag
454071, AI041793, Hs 42502, ESTs, breast , diag
454077, AC005952, Hs 37062, insulin-like 3 (Leydig cell), test, drag 454098, W27953, Hs 217493, Plakophil , lung, drag
454117, BE410100, Hs 40368, adaptor-related protein comple, mela, CTL+ε m
454360, L78207, Hε 54470, ATP-binding cassette, sub-fami, glio, mAb
454429, BE273437, Hs 301406, hypothetical protein PP3501, mela, mAb
454439, AW819152 Hs 154320, DKFZP56601646 protein, lung, diag 454478, AW805749, Hs 372783, superoxide dismutase 2, mitoch, mela, ε
455601, AI368680, Hs 816, SRY (sex determining region Y), lung, cerv, esoph, s m
456034, AW450979, , gb UI-H-BI3-ala-a-12-0-UI ε1 N, blad, fibro, drag
456062, AI866286, Hs 71962, ESTs, Weakly similar to B36298, fibro, ovar, uteπ diag 456177, NM_012391, Hs 79414, prostate epithelium specific E, breast, pros, drag
456266, L29073, Hs 198726, cold shock domain protein A, pane, CTL+s m
456321, NM_001327, Hs 87225, cancer/testis antigen, lung, CTL
456553, AA721325, Hs 189058, ESTs, Highly similar to Simila, pane, drag
456723, Z43902, Hs 4748, adenylate cyclase activating p, glio, mAb+s m
456736, AW248217, Hs 1619, xhaete scute complex (Drosoph, lung, drag
456759, BE259150, Hs 127792, delta (Drasophila) like 3, glio, lung, mAb
456847, AI360456, Hs 86088, ESTs, test, diag
456938, X52509, Hs 161640, tyrosine aminotransferase, breast, s m
456977, AK000252, Hs 169758, hypothetical protein FLJ20245, angio, diag
457200, U33749, Hs 197764, thyroid transcnption fxtor 1, fibro, CTL+s m
457211 , AW972565, Hs 32399, ESTs, Weakly similar to S51797, mela, pros, CTL+s m
457292, AI921270, Hs 281462, hypothetical protein FLJ14251, blad, mAb
457313, AF047002, Hs 241520, traπscπptional coxtivator, test, CTL+s m
457411, AW085961, Hs 130093, iroquois-class homeobox protei, breast, fibro, drag
457465, AW301344, Hs 122908, DNA replication factor, test, mela, drag
457498, AI732230, Hs 191737, ESTs, pros, drag
457561, AA331517, Hs 286055, chimeπn (chimaenn) 2, glio, mAb
457590, AI612809, Hs 5378, hypothetical protein MGC10724, ovar, drag
457869, AU077186, Hs 108885, Homo sapiens, alpha-1 (VI) col, sarc, CTL+s m
458092, W67353, Hs 350558, KIAA0251 protein, lung, drag
458124, AW005548, Hs 124590, ESTs, fibro, drag
458435, AI418718, Hs 144121, ESTε, Weakly similar to T46916, glio, diag
458471, AV648609, Hs 194240, ESTs, renal, pane, hepC, diag
458933, AI638429, Hs 24763, RAN binding protein 1, lung, test, diag
459373, BE408266, Hs 301406, hypothetical protein PP3501 , mela, mAb
459578, AW612538, Hs 304491, EST, mela, drag
459702, AI204995, , gb an03c03 x1 Stratagene schiz, blad, fibro, drag
459705, BE082764, Hs 270252, ESTs, Weakly similar to androg, fibro, mAb+s m
TABLE 3B
Pkey Unique Eoε probeεet identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT Number Accession
103739 49403_2 AA115173 AA075709 AA076354 AA083101 AA076396 AA085391 AA070684 AA083368 AA075779 AA075221 AA076395 AA650486 AA083500
108282 108971 AA065143AA065142
113230 2327174 1 AI820546 AI821336 T61430
118417 35983J AF080229 AF080232 U87593 U87592 U87591 U87590 AI636743 AI633818 AW206802 AI583718 AF080231 AF080234 AF080233 AL535594
AI818326 AF080230 S46404 AI970376 AA4639g2 AW665466 BF512210 U875g5 U87589 BE550633 AI672574 BE467547 AI680833 AW614951 N29986 N25695 H69001 U87596 BE673974 AI797496 AI701526 AA703396 AW139734 H92278 N66048 BE219539 BE671665 AI624817 BE466611 AI206344 AA574397 BF593413 BG231271 BF773517 U87594 BF062180 BE466420 AI887798 BF674385 AA204735 AW496808 AA204833 AA207155 BI004756 AA206262 A1365204 H77608 AW590511
121335 13692891 AA404418 AI217248
126872 6855861 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA482073 BE168845
322521 14637 AF147347 T55503T55426
3 32222997755 1 17788441155881 C16391 C16413
323332 2453011 AI829520 AI791832 AI791823 AA229315 AA228414 AA229211
323817 8878791 AA410943 BF366582 AA334202 AA332882 BF371899 AW948953
324261 10269761 AL044891 AI908240 AA393080 AW748403 BE068341 BF330573
406685 0_0 M18728
4 40099005511 1 10077993344JJ AA075419 AA082953 AA080912 AA062835 AA071252 AA084926 AA078992 AA113913 AA081881 AA070343 AA083821 AA062836 AA113892
AA075318 AA076594 AA078900 AA134801 AA063293 AA083403 AW974305
409123 1083781 AA070050 AA070823 AA063403
409745 MH1944_5 BI030997 AA921874 AW188822 BI027862 AI347618 A1361453 AI088754 AW207491 AA077391 BG012775 BG9g7382 AA286833 AA150722
BI007625 BI027864 BI009100 BI006275 BI006270 BI031000 BI029864 BI006277 BI007627 BI006266 BI006991 BI006990 BI007763 BI007762
BG9g7377 AA150780 BI033518 BI027818 BG015789 BI033807 AA341445
411880 11390831 BE088101 T05990 AW872477
413804 15566611 BE168256 BE168190 T64682
414221 6855861 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
417886 10313341 AA210987 D57294AA214584 AA207006 D56572
4 42277226600 1 1112277225500 AA401424 AA400100 AA663848
427298 1152411 AA933717 BF061897AW628327AA641788AA400495
427521 513212 AW073352 BF222g29 AW016853 BF059130 AI651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 AI206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892
429163 12382971 AW974271 AA592975 AA447312 AA884766
4 43322118899 1 11122771100_ϊ1 AA527941 AA635266 AI810608 AI620190
432222 5395291 BG207209 BE166299 AI204995 BG199355 AW969908 AA528756 AW440776 BI044354
432407 MH142912 BG036675 BF772005 BF771866 BG960386 BG960381 NMJ05712 AF110315 BE074534 BE182776 BE158000 BE157999 BE714315 AW818104
AW847519 AA099426 AW817981 AW856396 BG961122 AA224498 AA308542 AW821833 BF902155 AI732411 BG778834 BG283641 BE748279
BE748870 BG319540 BE748864 BF739224 BG986155 AK057283 BI861466 AA663341 AA457591 BG949294 AW392886 AA071122 AA227849
AA584918 BG959570 BF773486 AL041698 BF959013 R87170 C16859 BF770411 BF771298 AI075321 L13823 AA216700 BF771864 AW861859
BE537068 C18935AA155719 BF771172 BF769107 BF804964AW818172 AW818143AW392930 AW817057 AW858044 BF746211 AA179928
AW861687 AW821826 BI055726 BF242643 AA207189 BF770412 BF771157 BG430030 AA055592 432415 11371 1 BG166382 AW161086 N42363 BE935013 BE934g98 BG291451 AV700520 BG152773 AI224956 AI079635 AW054706 AA843979 AI744193 F04060
T23457 F04044 AA723859 AA977643 AA283764 AI123609 N21561 BF055052 BE856661 A1804220 AA843394 AI472045 AI740490 AA578830
H09495 AI283334 AA609495 AI122773 AW162643 AW161798 BF940077 AI808825 AI360866 AI123189 R40236 R20726 AW975899 BE764052
N31709 N31708 AI031947 AW194138 434414 35978J AF134164 BF809407 AA218567 BF842863 AI267168 BF876178 BG999253 AW861851 AW858362 AI817548 BF771300 AA113928 AA223422
AA055556 BF773400 BF998869 BE081333 BE073424 BE142245 H59571 H59570 BF871558 BF871064 BE001132 BF826831 AW754298 AA223267 BG997895 BG997897 AW991957 AA534354 BG319501 BF736309 AI694265 AA045564 BG950256 AI828309 BG987850 BE093175
BF854337
434596 14701 1 AF147374 T59538 T59589 T59598 T59542
434609 14739 1 AF1473gθ R76503 R76594
438966 1242593 1 AW979074AA834841 AA828650
438993 2580163 1 AI926361 AA834879 AA828995
439092 919640 1 AW978407 AA830149 M85983 AW503637 BF352096
439780 49082 1 AL109688 R23665 R26578
440151 1879911 1 AA868167 F21558 F31418 F35624
444163 682245 1 BG403189A1148521 AI184746 AI126098 R05933 BI057330
451844 2327174 1 A1820546 A1821336 T61430
456034 685586 1 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
459702 539529 1 BG207209 BE166299 AI204995 BG199355 AW96gg08 AA528756 AW440776 BI044354
TABLE 3C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLpositioπ Indicates nucleotide positions of predicted exons
Pkey Strand N position
325372 5866920 Minus 1117061-1117304
325544 6682452 Plus 171228-171286
327036 6531965 Plus 319951-320040
327075 6531965 Plus 40413184041431
327414 5867750 Plus 102461-102586
328700 5868264 Plus 764089-764203
330211 6013592 Plus 59158-59215
332798 Dunham, 1 etal Minuε 232147-231974
333769 Dunham, 1 et al Plus 7696625-7696707
333904 Dunham, 1 etal Minus 8217374-8217261
334223 Dunham, 1 etal Minus 12734365-12734269
334447 Dunham, 1 et al Plus 14308764-14308824
335115 Dunham, 1 etal Minus 21388250-21388146
335809 Dunham, 1 et al Plus 26310772-26310909
335824 Dunham, 1 et al Plus 26376860-26376942
335825 Dunham, 1 etal Plus 26378175-26378268
335936 Dunham, 1 etal Minus 27360474-27360400
336034 Dunham, 1 etal Plus 29014404-29014590
336152 Dunham, 1 etal Minus 30166053-30155870
336636 Dunham, 1 et al Plus 988418-989185
338008 Dunham, 1 etal Plus 7697068-7697236
338033 Dunham, 1 et al Plus 8092128-8092271
338158 Dunham, 1 etal Minus 11794465-11794343
338255 Dunham, 1 etal Minus 15242294-15242231
400494 9714719 Plus 169845-170272
400517 9796686 Minus 49996-50346
400651 8117978 Minus 81488-81646
400665 8118496 Plus 16879-17023
400773 8131629 Minus 44116-44238,4820848321
400844 9188605 Plus 24746-24872,25035-25204
400846 9188605 Plus 39310-39474
400881 2842777 Minus 91446-91603,92123-92265
401093 8516137 Minus 22335-23166
401234 9929642 Plus 120173-120337
401424 8176894 Plus 24223-24428
401486 7341763 Plus 32585-32756,36281-36540,4079140933,4401
401704 3097841 Plus 24712-25374
401732 1200312 Plus 19346-19525,19625-19708,19897-19973,2006
401747 9789672 Minus 118596-118816,119119-119244,119609-11976
401760 9929699 Plus 83126-83250,85320-85540,94719-95287
401780 7249190 Minus 28397-28617,28920-29045,29135-29296,2941
401781 7249190 Minus 83215-83435,83531-83656,83740-83901,8423
401785 7249190 Minus 165776-165996, 166189-166314,166408-16656
401797 6730720 Plus 6973-7118
401994 4153858 Minus 4290443124,4321143336,4460744763,4519
402145 8018280 Plus 113086-114800
402199 8576116 Minus 84187-84744
402230 9966312 Minus 29782-29932
402239 7690131 Plus 38175-38304,4213342266
402260 3399665 Minus 113765-113910,115653-115765,116808-11694
402265 3287673 Plus 21059-21168
402305 7328724 Plus 4083241362
402420 9796339 Plus 129750-129919
402424 9796344 Minus 64925-65073
402447 9796640 Plus 4760547729,51696-51821,52070-52257,5330
402474 7547175 Minus 53526-53628,55755-55920,57530-57757
402550 7652009 Minus 80413-80673
402604 9900420 Plus 20393-20767
402605 9909420 Minus 4768047973 402606 9909429 Minus 8174782094
402680 8113438 Plus 137634-137768,139702-139893,140475-14059
402777 9588235 Plus 126786-126948
402860 9588237 Minus 76423-76560
402888 9930892 Minus 54727-54901
402992 7767907 Minus 42137-42515
402994 2996643 Minus 47274969
403046 3540153 Minus 55707-55859,5636956511
403047 3540153 Minus 59793-59968
403071 8954241 Plus 136688-137096
403088 8954241 Plus 169894-170193,170504-170806
403171 9838164 Minus 74502-74703
403328 8469086 Minus 120428-120703
403329 8516120 Plus 96450-96598
403381 8438267 Minus 26009-26178
403409 9438598 Plus 6860-7054,12573-12771
403433 9719611 Minus 72225-72437
403478 9958258 Plus 116458-116564
403715 7239669 Plus 8512885292
403740 7630882 Plus 86504-87227
403776 7770611 Minus 1414-1513,1624-1756
403903 7710671 Minus 101165-102597
404029 7671252 Plus 108716-111112
404049 3688074 Minus 75765-78155
404210 5006246 Plus 169926-170121
404240 5002624 Minus 116132-116407,116653-116922
404253 9367202 Minus 55675-56055
404286 2326514 Plus 51086-51301
404298 9944263 Minus 73591-73723
404403 7272157 Minus 72053-72238
404440 7528051 Plus 80430-81581
404866 9366919 Minus 11743-11929
404877 1519284 Plus 1095-2107
404927 7342002 Plus 6869069563
404996 6007890 Plus 37999-38145,38652-3899839727-39872,4055
405001 6015406 Minus 104646-104819
405025 7107727 Plus 105267-105343,106184-106294,106387-10653
405121 8102330 Minus 35816-36004,36587-36684
405238 7248119 Minus 51728-51836
405239 7249119 Plus 144345-144464,144690-144836,151750-15188
405451 7622517 Minus 145949-146227
405545 1054740 Plus 118677-118807,119091-119296,121626-12182
405546 1054740 Plus 124010-124183
405547 1054740 Plus 124361-124520,124914-125050
405646 4914350 Plus 741-969
405704 4204244 Plus 138842-139051
405770 2735037 Plus 61057-62075
405849 7651817 Minus 17705-18287
405932 7767812 Minus 123525-123713
406081 9123861 Minus 38115-38691
406137 9166422 Minus 30487-31058
406173 7230224 Plus 12925-13213
406348 9255985 Minus 71754-71944
406360 9256107 Minus 7513-7673
406399 9256288 Minus 63448-63554
406434 9256651 Minus 17803-17931
406467 9795551 Plus 182212-182958
406506 7711374 Minus 6843-8077
406547 7711513 Minus 172780-174358
Table 4A lists about 425 genes up-regulated in breaεt cancer compared to normal adult tiεsues and to non malignant breaεt tiεεues These genes were selxted from a starting coltection of about 59680 probesets on the Affymetπx/Eos Hu03 GeneChip® array The "average" breast cancer level was set to the 90th percentite value amongst breast cancer specimens The "average" normal adult tissue level was set to the 75th percentite value amongst non-malignant adult tissues Certain predicted pratem domains are noted
Table 5A lists about 231 genes up-regulated in breast cancer compared to normal adult tissues and to non-malignant breast tisεues that are likely to encode proteins amenable to modulation by small mol∞ules, peptides, or antibodies These were selxted similariy as for Table 1 The "average" breast cancer level was set to the 90th percentite value amongst breast cancer spximenε The "average" normal adult tiεsue level was set to the 50th percentite value amongst non malignant adult tissueε The protein products of these genes often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being modulatable by small molecules, peptides, or antibodies (e g pkinase, death-domain, 7tm, phosphatase, or lonjransporter) Certain predicted protein domains are noted
TABLE 4A ABOUT 425 GENES UP-REGULATED IN BREAST CANCER COMPARED TO NORMAL ADULT TISSUES
Pkey Unique Eos probeset identifier number
ExAccn Exemplar accesεion number, GenBank xceεεion number
UniGenelD Unigene number
Pred Prot Domains Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain, =N, leεs likely to contain All other protein domain abbreviations are from PFAM (Nucleic Acids Reεearch, 2002, 30276-280) UmGeπe Title Unigene gene title
R1 Ratio of 90th percentite of tumor to 75th percentite of normal body tissue
Pkey ExAccn UniGenelD Pred Prot Domains UniGeneTitle R1 419551 AW582256 Hs 91011 TM=M,SS=M anteπor gradient 2 (Xenepus laevis 97
426174 AA547959 Hs 115838 Homo sapienε similar to Echinoidin 70
409340 BE174629 Hs 321130 aa_permeases,pyndoxal_de melaπophilin (MLPH), mRNA 68
428471 X57348 Hs 184510 14-3-3,TM=M,SS=N stratifin 64
417931 W95642 Hs 82961 trefoιl,TM=N,SS=M trefoil factor 3 (intestinal) 63
447966 AA340605 Hs 105887 Jacalιn,TM=N,SS=M ESTs, Weakly similar to Homolog of 61
406387 Target Exon 60
421814 L12350 Hs 108623 EGF.tsp 1,vwc,TSPN,tsp_3, thrombospoπdin 2 58
406867 AA157857 Hs 182265 filament bZIP,TM=N,SS=M keratin 19 58
426104 AI204418 Hs 190080 ESTs 58
421481 AW391972 Hs 104696 TM=M,SS=M KIAA1324 protein 58
422511 AU076442 Hs 117938 Collagen.none collagen, type XVII, alpha 1 57
426539 AB011155 Hε 170290 SH3,PDZ,Guanylate kιn,TM= discs, large (Drasophila) homolog 5 56
419693 AA133749 Hs 301350 ATP1G1 PLM MAT8,TM=Y,SS=M FXYD domain-containing ion transpor 55
419329 AY007220 Hs 288998 S_100,TM=M,SS=N S100 type calcium binding protein A 54
418344 AA216387 gb nc16b02s1 NCI CGAP_Pr1 Homo sap 52
407116 AA130986 Hs 271627 ESTs 51
417389 BE260964 Hε 82045 PTN_MK,TM=M,SS=Y midkme (neuπte growth promoting f 51
419452 U33635 Hs 00572 ιg,pkιnase,TM=Y,SS=M PTK7 protein tyrosine kinase 7 51
421552 AF026692 Hs 105700 Fz NTR,TM=N,SS=M secreted fπzzled related protein 4 51
409453 AI885516 Hs 95612 cadhenn cadheππ.Cadheπ ESTs 51
409632 W74001 Hs 55279 serpιn,TM=N,SS=N senne (or cysteine) proteinase inh 51
417515 L24203 Hs 82237 zf B box,zf-UBR1,TM=M,SS= ataxia telangiectasia group D assoc 50
411573 AB029000 Hs 70823 Sulfatase,TM=M,SS=N KIAA1077 protein 50
418751 BE389014 Hs 372548 SH2,none phosphomosιtιde-3-kιnase, regulato 50
422087 X58968 Hs 111301 fπ2,hemopexιπ,Peptιdase M matnx metaltoproteinase 2 (gelatin 50
421143 AB024536 Hs 102171 ιg,LRR,LRRNT,LRRCT,TM=M,S immunoglobulin superfamily containi 49
408491 A1088063 Hs 7882 ESTs 49
417944 AU077196 Hs 82985 vwc,Collagen,COLFI,TM=N S collagen, type V, alpha 2 49
409062 AL157488 Hs 50150 Homo sapiens mRNA, cDNA DKFZp564B18 49
422281 M36803 Hs 346935 hemopexιn,TM=N,SS=M hemopexin 49
425308 M97639 Hs 155585 ιg,kπngle,pkιπase Fz,TM= receptor tyrosine kmase-like orpha 48
408349 BE546947 Hs 44276 homeobox,TM=M,SS=N homeo box C10 48
-149019 AI949095 Hs 67776 ESTs, Weakly similar to T22341 hypo 48
435561 AA351978 Hs 4943 MAGE,Cys_knot,EGF,lamιnm hepatocellular carcinoma associated 48
410687 U24389 Hs 65436 Lysyl_oxιdase,TM=N,SS=M lysyl oxidase-like 1 48
429455 AI472111 Hs 278694 lectιn_c CD209 antigen 48
414407 AA147026 Hs 76704 ESTs 48
419390 AI701162 Hs 331904 PMP22_Claudιn,PMP22_Claud hypothetical pratem MGC11138 47
453902 BE502341 Hs 3402 ESTs 47
411089 AA456454 Hs 355702 cell division cycle 2 like 1 (PITSL 47
450172 NMJ05864 Hs 24587 SH3,hormone3,TM=M,SS=N signal transduction protein (SH3 co 47
449717 AB040935 Hs 23954 Glyco_tranεf_25,TM=N,SS=N cerebral cell adhesion molecule 46
451529 AI917901 Hs 208641 xtin.none ESTs 46
435370 AI964074 Hs 225838 EGF,fn3,fibπnogen C,toxι ESTs 46
411761 AI733848 Hs 71935 zf-C2H2,TM=M,SS=N putative zinc finger protein from E 46
424223 AJ243706 Hs 143323 PHD,ARID,jmjC,jmjN,zf-C5H putative DNA/chromatiπ binding moti 46
426935 NM_000088 Hs 172928 vwc,Collageπ,COLFI,TM=M,S collagen, type 1, alpha 1 45
408796 AA688292 Hs 170345 hormone reo,zf-C4 ESTs 45
407230 AA157857 Hs 182265 filament,bZIP,TM=N,SS=M keratin 19 44
422830 AC007954 Hs 121371 hypothetical protein DKFZp434P0111 44
447528 AI612027 Hs 76277 TB2_DP1_HVA22,TM=Y,SS=M Homo sapiens, clone MGC 9381, mRNA, 44
430168 AW968343 Hs 145582 efhand.efhaπd DKFZP434I1735 protein 44
423225 AA852604 Hs 125359 ιg,Rιbosomal_S19,TM=M,SS= Thy-1 cell surfxe antigen 44
414822 AA156542 Hs 72127 homeobox.HLH ESTε 44
452683 AI089575 Hs 374574 homeobox.noπe progesterone membrane binding prate 44
444784 D12485 Hs 11951 Somatomedin B.Eπdonucleas xtonucleotide pyrophosphatase/phoε 44
453857 AL080235 Hs 35861 TM=Y,SS=M Ras induced seneεcence 1 (RIS1) 44
413859 AW992356 Hs 8364 SAM_PNT,none Homo εapienε pyruvate dehydrogenase 43
440369 AW176150 Hs 132449 downstream of breast cancer antigen 43
418140 BE613836 Hs 83551 TM=M,SS=M microfibπllar-aεsocrated protein 2 43
441384 AA447849 Hs 288660 7tm_3,none retinoic xid induced 3 43
424464 R68537 Hs 17962 homeobox.noπe ESTs 43
423582 BE000831 Hs 23837 TGFb_propeptιde,TGF-beta, Homo sapienε cDNA FU11812 fiε, do 43
432562 BE531048 Hs 278422 zf C2H2,TM=M,SS=N DKFZP586G1122 protein 42
433320 D60647 Hs 250879 rrm ESTε, Highly similarto CTXN RAT CO 42
429165 AW009886 Hs 118258 prostate cancer associated protein 42
416984 H38765 Hs 80706 Flavodoxιn_2,TM=M,SS=N diaphorase (NADH/NADPH) (cytochrome 42
448913 AA194422 Hs 22564 rrrαzf RanBP,pkιπase,GST_ myosin VI 42
430154 AW583058 Hs 234726 εeφin,TM=M,SS=M seπne (or cysteine) proteinase inh 42
400496 TM=Y,SS=N ENSP00000224716* GTP-bmding protei 42
442599 AF078037 Hs 324051 SH3,aπk,TM=M,SS=N RelA associated inhibitor 42
448520 AB002367 Hs 21355 pkιnase,DCX,TM=M,SS=N doubl∞ortin and CaM kmase-like 1 42
431309 AW451711 Hs 313760 homeobox.noπe ESTs, Weakly similar to I38022 hypo 42
426485 NMJ06207 Hs 170040 ιg,TM=N,SS=M platelet-deπved growth fxtor rxe 42
435858 AF254260 Hs 283009 bZIP,TM=M,SS=N tuftelm 1 42
446051 BE048061 Hs 37054 Ephππ,A deamiπ.dεrm z-al ephπn-A3 42
451982 F13036 Hs 27373 NA.NA Homo sapienε mRNA, cDNA DKFZp564017 42
450334 AF035959 Hs 24879 PAP2,TM=Y,SS=M phoεphaddic xid phosphatase type 41
431890 X17033 Hs 271986 vwa.integππ A,FG-GAP,TM= integπn, alpha 2 (CD49B, alpha 2 s 41
434449 AW953484 Hs 3849 efhand,FKBP,TM=M,SS=N hypothetical protein FU22041 simil 41
422699 BE410590 Hs 119257 SH3.HS1 rep,TM=M,SS=N ems1 εequeπce (mammary tumor and sq 41 423057 AW961597 Hs.130816 ESTs, Moderately similar to I38022 4.1
452063 R53185 Hs.32366 HLH;TM=M;SS=N ESTs, Weakly similar to TWST_HUMAN 4.1
450680 AF131784 Hs.25318 ras.none Homo sapienε clone 25194 mRNA seque 4.1
418283 S79895 Hs.83942 Peptidase_C1;TM=N;SS=M cathepsin K (pycnodysostosiε) 4.1
416361 AW204907 Hs.6872 ESTε, Weakly similar to CA13_HUMAN 4.1
426255 BE262530 Hs.2006 GST_C,GST_N;TM=M;SS=N glutathione S-transferase M3 (brain 4.1
408113 T82427 Hs.194101 7tm_3,noπe Homo sapienε cDNA: FLJ20869 fis, el 4.1
407792 AI077715 Hs.39384 TM=M;SS=Y putative secreted ligand homologous 4.1
422765 AW409701 Hs.1578 BIR;TM=M;SS=N bxuloviral IAP repeat-containing 5 4.1
429359 W00482 Hε.2399 hemopexin.Peptidase M10;T matrix metaltoproteinase 14 (membra 4.1
442572 AI001922 Hs.135121 HSP70 hypothetical protein FLJ22415 4.0
448826 AI580252 Hs.255565 ESTs, Weakly similar to putative p1 4.0
419648 T73661 Hs.91877 TM=N;SS=M thyroid hormone responεive SPOT14 ( 4.0
421485 AA243499 Hs.104800 TM=Y;SS=M hypothetical protein FU10134 4.0
440273 AI805392 Hs.325335 Homo εapienε cDNA: FLJ23523 fiε, cl 4.0
417363 AW129357 Hs.329700 ESTε 4.0
451277 AK001123 Hs.26176 TM=Y;SS=M hypothetical protein FLJ10261 4.0
421823 N40850 Hs.28625 ESTε 4.0
452239 AW379378 Hs.356289 protein tyrosine phosphatase, rxep 4.0
444286 AI625304 Hs.201008 ESTs 4.0
451541 BE279383 Hs.26557 Armadillo seg;TM=M;SS=N plakophilin 3 4.0
451304 M92642 Hs.26208 Collagen,TSPN;TM=M;SS=M collagen, type XVI, alpha 1 4.0
429556 AW1393g9 Hs.314807 TM=M;SS=N ESTs 4.0
441094 U33819 Hs.7647 zf-C2H2,LIM,PHD,TFIIS;TM= MYC-ass∞iated zinc finger protein 4.0
407788 BE514982 Hs.38991 efhand.S 100.S 100,efhaπd S100 calcium-binding protein A2 4.0
451292 AB037716 Hs.26204 SH3;TM=M;SS=N KIAA1295 protein 3.9
437762 T78028 Hs.154679 C2,none synaptotagmin I 3.9
433399 N46406 Hs.84700 START;TM=M;SS=N similar to phosphatidylcholine tran 3.9
408056 AA312329 Hs42331 Ephrin;TM=M;SS=M ephrin-A4 3.9
404578 AF183810 Hs.26102 zf-C2H2,rubredoxin;TM=M;S trichorhinophalangeal syndrome I gene 3.9
443883 AA114212 Hs.9930 εerpin;TM=M;SS=M serine (or cysteine) proteinase inh 3.9
445084 H38914 Hs.250848 TM=Y;SS=M hypothetical protein FLJ14761 3.9
453880 AI803166 Hs.135121 HSP70,none ESTs, Weakly similar to I38022 hypo 3.9
424125 M31669 Hs.1735 TGF-beta,TGFb propeptide; inhibin, beta B (xtivin AB beta po 3.9
437377 AL359573 Hs.124940 raε;TM=M;SS=N GTP-binding protein 3.9
422562 AI962060 Hs.118397 Zn carbOpeptF5 F8 type C AE-binding protein 1 3.9
422320 AI745249 Hs.23650 TM=Y;SS=N ESTs, Weakly similar to AAB47496 NG 3.9
433078 AW015188 Hs.121575 aεp Homo sapiens cDNA FU12231 fis, clo 3.9
411894 M57609 Hs.72916 zf-C2H2;TM=N;SS=M GLI-Kruppel family member GLI3 (Gre 3.9
425976 C75094 Hs.334514 voltage_CLC;TM=Y;SS=M NG22 protein 3.9
418113 AI272141 Hs.83484 HMG_box,homeobox;TM=M;SS= SRY (sex determining region Y)-box 3.9
418753 BE217818 Hs.87016 hypothetical protein FU22938 3.8
452679 Z42387 Hs.83883 TM=Y;SS=M transmembrane, prostate aπdrogen in 3.8
421030 AW161357 Hs.101174 tubulin-binding;TM=N;SS=M microtubule-aεεociated protein tau 3.8
431567 N51357 Hs.260855 TM=M;SS=N Homo sapiens cDNA: FU21410 fis, cl 3.8
426363 M58524 Hs.2025 TGF-beta,TGFb_pro peptide; transforming growth fxtor, beta 3 3.8
447151 AI022813 Hs.92679 kineεin;TM=M;SS=M Homo sapiens clone CDABP0014 mRNA s 3.8
448717 R67410 Hs.21851 HLH.homeobox.none Homo sapiens cDNA FU12900 fis, clo 3.8
425867 D60385 Hs.12079 cadherin;TM=Y;SS=M calsyntenin-2 3.8
423940 NMJ1242S I Hs.277728 CRAL_TRIO;TM=M;SS=N SEC14 (S. cerevisiae)-tike 2 3.8
426742 AA383828 Hs.181131 ESTs 3.8
435818 AA700553 Hs.368614 arf,ras,RecR,none ESTs 3.8
420005 AW271106 Hs.133294 ESTs 3.8
410867 X63556 Hs.750 EGF,TB,wnt,EB,TIL;TM=N;SS fibrillin 1 (Marfan syndrome) 3.8
402531 AB037745 Hs.104696 TM=M;SS=M KIAA1324 protein 3.8
449029 N28989 Hs.22891 aa_permeases;TM=Y;SS=M solute earner family 7 (cationic a 3.8
424806 AA382523 Hs.105689 TM=Y;SS=N MSTP031 protein 3.8
443933 AI091631 Hs.203845 ion_trans;TM=Y;SS=M two pore potaεεium channel KT3.3 3.8
432952 AA813887 Hs.188173 Homo sapienε cDNA FU12187 fis, clo 3.8
424036 AA770688 Hs.348495 histone,CBFD_NFYB_HMF;TM= H2A histone family, member L 3.7
453828 AW970960 Hs.293821 Pep_M12B_propep,Reprolysi ESTs 3.7
407112 AA070801 Hε.51615 hormoπe_rec,zf-C4 ESTs, Weakly similarto ALU7_HUMAN 3.7
445669 AI570830 Hs.174870 ESTs 3.7
446091 AW022192 Hs.200197 hom∞box.none ESTs 3.7
424651 AI493206 Hs.120785 ESTs 3.7
409178 BE393948 Hs.50915 trypsin;TM=M;SS=Y kallikrein 5 3.7
417059 AL037672 Hs.81071 TM=N;SS=Y extrxellular matrix protein 1 3.7
431194 D43704 Hs.250712 Ca channel B,RepB_protein calcium channel, voltage-dependent, 3.7
430397 AI924533 Hs.105607 HC03 cotraπsp;TM=Y;SS=N bicarbonate transporter related pro 3.7
418969 W33191 Hs.28907 SH3;TM=M;SS=N hypothetical protein FU20258 3.7
427378 BE515037 Hs.177556 MAGE;TM=M;SS=N melanoma antigen, family D, 1 3.7
424012 AW368377 Hs.137569 SAM,P53;TM=M;SS=N .tumor protein 63 kDa with εtrong ho 3.7
418840 AI821614 Hs.185831 ESTε 3.7
433573 AF234887 Hs.57652 7tm_2,EGF,cadherin,lamini cadhenn, EGF LAG εeven-pass G-type 3.7
433430 AI863735 Hs.369982 thyroglobulin 1,IGFBP,zf- ESTs 3.7
422491 AA338548 Hs.117546 TM=M;SS=Y neuronatin 3.7
435114 AA775483 Hs.288936 ODC AZ,Ribosomal L9 N;TM= mitochondrial ribosomal protein L9 3.7
416899 BE262645 Hs.80420 IL8;TM=M;SS=M εmall inducible cytokine subfamily 3.7
422110 AI376736 Hs.121555 kazal.none secreted protein, xidic, cysteine- 3.7
448560 BE613183 Hε.23213 zf-RanBP,MDM2,Ndr ESTs 3.6
414945 BE076358 Hs.77667 UPAR LY6;TM=M;SS=M lymphocyte antigen 6 complex, tocus 3.6
422119 AI277829 Hs.111862 WD40;TM=M;SS=N KIAA0590 gene product 3.6
447335 BE617695 Hs.286192 TM=M;SS=N hypothetical protein FU20940 3.6 450663 H43540 Hs 25292 RNaεe_HII,TM=N,SS=M πbonuclease HI, large subunit 36
417387 AW021102 Hs 21509 zf-C2H2,noπe ESTs 36
450825 AC005954 Hs 25527 PDZ,Guanylate kιn,TM=N,SS tight junction protein 3 (zona occl 36
439755 AW748482 Hs 77873 ιg,TM=Y,SS=M B7 homolog 3 36
439873 BE159253 Hs 300638 ESTs 36
439039 AI656707 Hs 48713 pkmaεe.none ESTs 36
419235 AW470411 Hs 288433 πeurotπmin 36
445033 AV652402 Hs 72901 ank,TM=N,SS=N cyclin-depeπdeπt kinase inhibitor 2 36
404394 AF332975 Hs 307004 EGF,fn1,vwc,vwd,MAM,Kerat Zonadhesm 36
452222 AW806287 Hs 21432 Sema,TIG,PSI,GDI SEX gene 36
422961 Y13620 Hs 122607 TM=M,SS=N B-cell CLL/lymphoma 9 36
420988 AW006352 Hs 159643 ESTs, Weakly similar to T32554 hypo 36
439680 AW245741 Hs 58461 zf-C2H2,TFIIS,KRAB,TM=M,S ESTs, Weakly similar to A35659 krue 36
426815 D59505 Hs 351344 ιg,SET,PHD,zf CXXCAdap_c ESTs, Weakly similar to K1 CLHUMAN 36
437446 AA788846 Hs 101302 fn3,vwa,Collagen,TSPN,TM= ESTs, Moderately similar to CA1 C RA 36
421690 AW162667 Hs 106857 efhand,TM=M,SS=N calbiπdm 2, (29kD, calretinin) 35
453939 AA418160 Hs 86043 Homo sapiens cDNA FLJ13558 fis, clo 35
426158 NM_001982 Hs 199067 Fuπn-lιke,pkιnase,Recep_ v-erb-b2 avian erythroblastic leuke 35
439246 AI498072 Hs 351474 aπk,pkιnase,UPF0073,TM=N, membrane-associated tyrosine- and t 35
410653 BE383768 Hs 65238 zf-C3HC4,AIP3,TM=M SS=N 95 kDa retinoblastoma protein bmdi 35
412703 AW984744 gb RC1-HN0015-040400 011-d03 HN0015 35
427871 AW992405 Hs 352406 TM=M,SS=N Homo sapiens, clone IMAGE 3507281, 35
444273 AI903474 Hs 230 LRR,LRRNT,TM=M,SS=M fibromodulm 35
434936 AI285970 Hs 183817 UCH-2 ESTs 35
457869 AU077186 Hε 108885 vwa,Collagen,TM=M,SS=M Homo sapiens, alpha-1 (VI) collagen 35
422575 AK000546 Hs 118552 PTR2,TM=Y,SS=M hypothetical protein FU20539 35
428343 AL043021 Hs 12705 WD40,TM=N,SS=M ESTs 35
426716 NMJ06379 Hs 171921 ιg,Sema,PSI,TM=N,SS=M sema domain, immunoglobulin domain 35
423778 Y09267 Hs 132821 FMO-lιke,pyr redox,TM=Y,S flavin containing monooxygenase 2 35
451558 NM 001089 Hs 26630 ABC tran,SRP54,TM=Y,SS=M ATP binding caεεette, sub-family A 35
407926 AW956382 Hs 59771 TYA,TM=N,SS=M ESTs 35
447041 AL135480 Hs 250705 Homo sapiens cDNA FLJ 11685 fiε clo 35
419073 AW372170 Hs 183918 death,ZU5,TM=N,SS=M Homo sapiens cDNA FU 12797 fis, clo 35
446945 AI193115 Hs 16611 TM=M,SS=N tumor protein D52-lιke 1 35
416322 BE019494 Hs 79217 P5CR.NAD Gly3P dh.Octop pyrrolme 5-carboxylate reductase 1 35
447347 AA570056 Hs 122730 NA.NA ESTs, Moderately similar to KIAA121 35
448984 AW751955 Hs 22753 TM=M,SS=N hypothetical protein FLJ22318 35
421778 AA428000 Hs 283072 NA.NA xtin related protein 2/3 complex, 35
423363 BE544348 Hs 127562 homeobox,TM=M,SS=N homeo box C11 35
432545 X52486 Hs 3041 cyclin.none uracil-DNA glycosylaεe 2 35
408495 W68796 Hs 237731 ESTε 35
406851 AA609784 Hs 352392 ιg,MHCJI_beta,TM=M,SS=Y major hiεtocompalibility complex, c 35
418736 T18979 Hs 87908 helicase CAT hook,SNF2_N Snfe-related CBP xtivator protein 34
410197 NM 005518 Hs 59889 HMG_CoA_synt,TM=N,SS=N 3-hydroxy-3-methylglutaryl-Coenzyme 34
453597 BE281130 Hs 33713 KH-domaιn,Rιbosomal_S3_C, myo-inositol 1-phosphate synthase A 34
417259 AW903838 Hs 81800 EGF.ig lectιn_c,sushι,Xlι chondroitin sulfate proteoglycan 2 34
453985 N44545 Hs 251865 PH.none ESTs 34
412634 U55984 Hs 356531 heatsh∞k90kD protein 1, alpha 34
407204 R41933 Hs 140237 hiεtone.histone ESTε, Weakly similar to ALU1_HUMAN 34
444371 BE540274 Hs 239 Fork_head,TM=M,SS=N forkhead box M1 34
447334 AA515032 Hε 91109 ESTs 34
426530 U24578 Hs 278625 A2M,NTR,ANATO,A2M_N,preny complement component 4A 34
419749 X73608 Hs 93029 kazal,thyroglobulιn_1,TM= sparc/osteonectin, cwcv and kazal I 34
423595 R82826 Hs 220702 homeobox.none ESTs 34
406673 M34996 Hs 198253 ig.MHC II alpha,TM=M,SS=M major histocompatibility complex, c 34
434241 AF119913 TM=N,SS=M Homo sapiens PRO3077 mRNA, complete 34
412490 AW803564 Hs 288850 Homo sapiens cDNA. FU22528 fis, cl 34
452277 AL049013 Hs 28783 ank,TM=M,SS=N KIAA1223 protein 34
431457 NM 012211 I Hs 256297 FG-GAP,vwa,TM=Y,SS=M integπn, alpha 11 34
421777 BE562088 Hs 108196 TM=M,SS=N HSPC037 protein 34
453082 H18835 Hs 31608 ion trans,TM=Y,SS=M hypothetical protein FU20041 34
414085 AA114016 Hs 75746 aldedh,TM=N,SS=M aldehyde dehydrogenase 1 family, me 34
440300 N39760 Hs 8859 TM=M,SS=N Homo sapiens, Similarto RIKEN cDNA 34
400290 H18836 Hs 31608 Cyε knot hypothetical protein FU20041 34
433339 AF019226 Hs 8036 ras,arf,TM=M,SS=N glioblastoma overexpressed 34
419301 AA236166 Hs 132957 TM=Y,SS=M tenomodulin protein 34
414792 BE314949 Hs 87128 TM=Y,SS=M hypothetical protein FU23309 34
451428 AW083384 Hs 11067 ESTs, Highly similar to T46395 hypo 34
432210 AI567421 Hs 273330 EGF,kazal,lamιnιn_EGF,lam Homo sapienε, clone IMAGE 3544662, 34
452242 R50956 Hs 159993 gycosyltransferase 34
450676 AI147155 Hs 279727 ESTs 34
413014 AW250533 Hs 75139 TM=M,SS=N partner of RAC1 (arfaptin 2) 34
427919 AA173942 Hs 326416 CTF NFI,none Homo sapiens mRNA, cDNA DKFZp564H19 34
424005 AB033041 Hs 137507 TM=Y,SS=N vang (van gogh, Drasophila) like 2 34
422072 AB018255 Hs 111138 RhoGAP,TM=M,SS=N KIAA0712 gene product 34
440995 T57773 Hs 10263 ESTs 34
426150 NMJ03658 Hs 167218 homxbox,TM=N,SS=M BarH like homeobox 2 33
416877 BE386266 Hs 85658 zf C2H2,TM=M,SS=N hypothetical protein FU23436 33
452191 AU076408 Hs 28309 UDPG_MGDP_dh,UDPG_MGDP_dh UDP-glucose dehydrogenase 33
450273 AW296454 Hs 24743 rrm.none hypothetical protein FU20171 33
456177 NM_012391 Hs 79414 Ets,SAM_PNT,TM=M SS=N prostate epithelium specific Ets tr 33
423062 NM 003655 Hε 5637 chromo,TM=N,SS=M ESTε 33
421848 X15880 Hs 108885 vwa,Collagen,TM=M,SS=M collagen, type VI, alpha 1 33 433577 AW007080 Hs 284192 ESTε 33
409636 AA305729 Hs 18272 Aa trans,TM=Y,SS=N ammo xid tranεporter εystem A1 33
404730 AA486704 Hs 33287 CTF_NFI none Nuclear fxtor l/B 33
422940 BE077458 S∞7,PH ANF_rxeptor,lιg gb RC1-BT0606-090500-015-b04 BT0606 33
410001 AB041036 Hs 57771 trypsιn,TM=M,SS=M kallikrein 11 33
427461 AA531527 Hs 332040 TM=Y,SS=M hypothetical protein MGC13010 33
453468 W00712 Hs 32990 TM=M,SS=N DKFZP566F084 protein 33
443807 W52930 Hs 9822 HAT,TM=N,SS=M HCNP protein, XPA-bmdmg pratem 2 33
456034 AW450979 gb Ul-H BI3-ala-a-12 0-UI s1 NCI_CG 33
424307 AW2933g9 Hs 356377 nuclear receptor co-represεor 1 33
412755 BE144306 Hs 179891 ESTε, Weakly similar to P4HA_HUMAN 33
429690 AW956329 Hs 23721 sugar tr.Ribosomal S25 ESTs 33
423472 AF041260 Hs 129057 TM=M,SS=N breast carcinoma amplified sequence 33
424118 BE269041 Hs 140452 peπlιpιn,TM=N,SS=M cargo selxtion protein (mannoεe 6 33
437275 AW976035 Hs 292396 Fπzzled Fz ESTs, Weakly similar to A47582 B-ce 33
437464 AA323296 Hs 97837 Homo sapienε mRNA, cDNA DKFZp547J04 33
433592 NM 004642 Hs 3436 TM=M,SS=N deleted in oral cancer (mouse, homo 33
434931 AW968941 Hs 166254 hypothetical protein DKFZp566H33 33
451691 AI809278 Hs 208152 C2 ESTs 33
430433 AA478883 Hs 273766 WW.none ESTs 33
429343 AK000785 Hs 199480 VHS,ENTH,UIM,TM=N,SS=M Homo sapiens, Similar to epsm 3, c 33
450835 BE262773 Hs 25584 ArfGap,TM=N,SS=M hypothetical protein FU 10767 33
414591 AI888490 Hs 248107 ESTs, Weakly similar to ALU8 HUMAN 33
452579 AA131657 Hs 23830 CNJiydrolase ESTs 33
409960 BE261944 Hs 355264 hexokmase 1 33
406850 AI624300 Hs 172928 vwc,Collagen,COLFI,TM=M,S collagen, type 1, alpha 1 33
453874 AW591783 Hs 36131 collagen, type XIV, alpha 1 (unduli 32
425964 AW889928 Hs 9071 hom∞box.none progesterone membrane binding prote 32
428412 AA428240 Hs 126083 ESTs 32
430316 NM 000875 Hs 239176 th3,Fuπn lιke,pkιπase,Re insulin-like growth fxtor 1 rxept 32
440087 W28969 Hs 7718 KOW.Ribosomal S4e,S4,rrm, hypothetical protein FU22678 32
449933 AW157098 Hs 324104 DUF176,efhand,TM=M,SS=N - Human DNA sequence from clone RP1-6 32
441128 AA570256 Hs 348504 TM=Y,SS=M ESTε, Weakly similar to T23273 hypo 32
434182 W20309 Hs 8107 G-gamma,TM=M,SS=N G-protem gamma-12 subunit 32
422737 M26939 Hs 119571 Collagen,COLFI,TM=N,SS=M collagen, type III, alpha 1 (Ehlers 32
408202 AA227710 Hε 43658 OLF,TM=M,SS=N DKFZP586L151 protein 32
424971 AA479005 Hs 154036 PH,TM=M,SS=N tumor suppreεεing subtransferable c 32
407869 AI827976 Hs 24391 efhaπd,TM=M,SS=N hypothetical protein FU13612 32
444734 NM_001360 Hs 11806 ERG4_ERG24,TM=Y,SS=M 7-dehydrocholeεterol reductaεe 32
426991 AK001536 Hs 214410 Homo sapiens cDNA FL) 10674 fis, clo 32
414081 AW969976 Hs 365706 gla,TM=N,SS=Y matnx Gla protein 32
408795 AW749126 Hs 170345 hormone rec,zf-C4 hypothetical protein FLJ13710 32
452345 AA293279 Hs 29173 DSPc,TM=M,SS=N hypothetical protein FU20515 32
437879 BE262082 Hs 5894 TM=N,SS=N hypothetical protein FL 10305 32
407872 AB039723 Hs 40735 Fz,Fnzzled,7tm_2,DUF81,T fπzzled (Drasophila) homolog 3 32
427289 AI097346 Hs 323878 ammotran 5,SDF,none phosphosenne aminotransferase 32
432375 BE536069 Hs 2962 efhand.S 100,TM=N,SS=M S100 calcium-binding protein P 32
429415 NM 002593 Hs 202097 CUB,NTR,TM=N,SS=M procollagen C-eπdopeptidase enhance 32
412774 AA120865 Hs 380149 hormone reo,zf C4 ESTs 32
445942 T80334 Hs 13479 TM=M,SS=N hypothetical protein FU20847 32
439456 AI752409 Hs 109314 zf-C2H2,TM=N,SS=M hypothetical protein FU20980 32
414774 X02419 Hs 77274 kπngle,trypsιn,plant_thι plaεmmogen xϋvator, urokinaεe 32
433336 AF017986 Hs 31386 Fz,NTR,TM=N,SS=M s∞reted fπzzled related protein 2 32
439905 AW799755 Hs 110953 HLH,TM=M,SS=N retinoic xid induced 1 32
420251 AW374968 Hs 379829 Human DNA sequence from clone RP5-1 32
413004 T35901 Hs 75117 TM=M,SS=N interleukin enhancer binding fxtor 32
418686 Z36830 Hs 87268 annexιn,TM=M,SS=N annexin A8 32
410279 BE271977 Hs 61809 ras,TM=M,SS=N hypothetical protein FU14117 32
424391 BE550112 Hs 158549 ESTs, Weakly similar to T2D3JHUMAN 32
440409 AW294316 Hs 125608 thiored ESTs 32
452689 F33868 Hs 284176 transfemn,KH-domaιn,rrm traπsferπn 32
418154 BE165866 Hs 352403 hormone_rec,zf-C4,none nuclear receptor subfamily 1 , group 32
434384 AA631910 Hs 370133 ESTs 32
413436 AF238083 Hs 68061 DAGKc,TM=M,SS=N sphingosme kinase 1 32
431663 NM 016569 Hs 267182 T-box,TM=M,SS=N TBX3-ιso protein 32
432874 W94322 Hs 279651 SH3,TM=M,SS=Y melanoma inhibitory activity 32
436252 AI539519 Hs 142827 Homo sapienε cDNA FU 11562 fis, clo 32
421044 AF061871 Hs 101302 fn3,vwa,Collagen,TSPN,TM= Human DNA sequence from clone RP1-2 32
419102 AA234098 Hs 42424 ESTs, Weakly similar to 2004399A ch 32
419359 AL043202 Hs 90073 CAS_CSE1,TM=M,SS=N chromosome segregation 1 (yeast hom 32
441859 AW194364 Hs 9877 Ammo oxidase.FAD binding ιnterieukιn4 induced gene-1 protei 31
426418 M90464 Hs 169825 Collagen,C4,VPR,TM=N,SS=M collagen, type IV, alpha 5 (Alport 31
413076 U10564 Hs 75188 pkmase,TM=M,SS=N weel (S pombe) homolog 31
407874 AI766311 Hs 289047 COQ7 Homo sapienε cDNA FLJ14059 fis, do 31
448019 AW947164 Hs 195641 ESTs, Moderately similarto I38022 31
427024 AA397572 Hs 348902 chromosome 11 open reading frame 14 31
410281 AF076612 Hs 166186 vwc,W2,MA3,MIF4G Homo sapiens done 23928 mRNA seque 31
447205 BE617015 Hs 11006 LEA,penlιpιn,TM=M,SS=N ESTs, Moderately similar to T17372 31
434433 AW629759 gb hh70e05 y1 NCI_CGAP_GU1 Homo sap 31
439737 AI751438 Hs 41271 C1q,0ollagen,none Homo sapiens mRNA full length inser 31
450157 AW961576 Hs 60178 PH,Band_41,RhoGEF,none ESTs 31
445989 H97754 Hs 11108 ESTs 31
442213 N36110 Hs 305971 sugar jπTM=Y,SS=M solute earner family 2 (facilitate 3 1 402496 Target Exon 31
438974 AF089816 Hs 6454 PDZ,TM=N,SS=M chromosome 19 open reading frame 3 31
439335 AA742697 Hs 62492 TM=N,SS=M NM_052863 Homo sapienε ε∞retoglobi 31
412276 BE262621 Hs 73798 MIF,sugar_tr,none mxrophage migration inhibitory fx 31
416950 AL049798 Hs 80552 dermatopontiπ 31
456157 AW979153 Hs 336881 traπsmembraπe4,none ESTs 31
452753 AA028049 Hs 277728 CRAL TRIO.none SEC14 (S cerevisiae) like 2 31
414420 AA043424 Hs 76095 TM=M,SS=N immediate early responεe 3 31
446229 AI744964 Hε 14449 TM=M,SS=N KIAA1609 protein 31
453143 AA382234 Hε 356289 εerpιn,TM=N,SS=M protein tyrosine phosphatase, recep 3 1
411441 AL042355 Hs 70202 WD40,TM=M,SS=N WD repeat domain 10 31
422921 BE062045 Hs 351625 AAA hormone rec,zf C4 Homo sapiens cDNA FLJ23260 fis, cl 3 1
444441 AW613841 Hs 301304 IRK,TM=Y,SS=N hypothetical protein MGC3101 31
436729 BE621807 Hs 351316 TM=Y,SS=M transmembrane 4 superfamily member 31
427890 AA435761 Hs 373623 RFX_DNA_bιndιng none ESTs 31
444838 AV651680 Hs 208558 ιntegπn_A,FG-GAP,none ESTs 31
427876 AI494291 Hs 369171 ESTs 31
413040 AA193338 Hs 12321 Na Ca Ex,TM=Y,SS=M sodium calcium exchanger 31
427515 T79526 Hs 179516 EMP24 GP25L,TM=Y,SS=M integral type I protein 31
451092 AI207256 Hs 13766 filament,TM=N,SS=N Homo sapiens mRNA for FU00074 prot 31
442222 AI061301 Hs 164773 trypsιπ,kπngle,UPAR_LY6 ESTs 31
452613 AA461599 Hs 23459 ESTs 31
447191 NM 014521 Hs 17667 SH3,TM=M,SS=N SH3-domaιn binding protein 4 31
412890 T85247 Hs 351875 COX6C,TM=M,SS=M cytochrome c oxidase subunit Vic 31
418313 BE244231 Hε 84038 TM=Y,SS=N CGI 06 protein 31
440006 AK000517 Hε 6844 AAA.NB ARC,PAAD_DAPIN,NA, NALP2 protein, PYRIN Containing APA 31
434042 AI589941 Hs 8254 Homo sapiens, Similar to tumor diff 31
420576 AA297634 Hs 54925 KIAA1858 protein 31
432269 NM 002447 Hε 2942 pkιnase,Sema,PSI,TIG A4_E mxrophage stimulating 1 rxeptor ( 31
424927 AW973666 Hs 153850 hypothetical protein C321D24 31
440100 BE382685 Hs 158549 ESTs, Weakly similar to T2D3_HUMAN 31
452408 AA306477 Hs 29379 TM=M,SS=N hypothetical protein FLJ10687 31
441362 BE614410 Hs 23044 TM=N,SS=N RAD51 (S cerevisiae) homolog (E co 31
418444 AI902899 Hs 85155 zf CCCH,TM=M,SS=N butyrate response fxtor 1 (EGF-res 31
423464 NM 016240 Hs 128856 Collagen,TM=Y,SS=N CSR1 protein 31
424604 AW865388 Hs 151076 TM=M,SS=N KIAA1243 protein 31
420059 AF161486 Hs 94769 ras.none RAB23, member RAS oncogene family 31
453271 AA903424 Hs 6786 LIM,TM=M,SS=N ESTε 31
411274 NM 002776 Hs 69423 trypsιn,TM=M,SS=N kallikrein 10 31
434095 AA011117 Hs 3745 EGF.F5 F8 type_C,TM-N,SS= milk fat globule-EGF fxtor 8 prate 31
403439 aπk,TM=M,SS=N NM_031419* Homo sapiens motecule po 31
413244 AW955951 Hs 159265 BTB,Pep_M12B_propep Repro kruppel related zinc finger protein 31
411756 BE294350 Hs 71891 pkιnase,F5_F8_type_C,TM=Y discoidm domain receptor family, m 31
409007 AL122107 Hs 49599 Homo sapiens mRNA, cDNA DKFZp434G08 31
452547 AA335295 Hs 74120 LEA,TM=M,SS=N adipose spxific 2 31
414359 M62194 Hs 75929 cadheπn,Cadheππ_C_term, cadhenn 11, type 2, OB-cadheπn (o 31
433212 BE218049 Hs 121820 ESTs 31
449123 D50920 Hs 23106 TM=M,SS=N KIAA0130 gene product 31
431176 AI026984 Hs 293662 MCPsιgnal,lamιnιn_B,lamιn ESTs 30
419245 AI732742 Hs 87440 ESTs 30
434493 AA635305 Hs 375591 ESTs 30
449177 BE616694 Hs 288042 hypothetical protein FU14299 30
430449 AA352723 Hs 241471 WH1,TM=M,SS=N RNB6 30
452887 AI702223 Hs 107253 K-box,TM=N,SS=M hypothetical protein DKFZp761F241 30
451678 AA374181 Hs 26799 DKFZP564D0764 protein 30
445457 AF168793 Hs 12743 Cam xyltranεf;TM=M,SS=N camitine 0-oetanoyltransferase 30
407597 AA043925 Hs 339352 fn3,ιg,TM=Y,SS=M Homo εapienε brother of CDO (BOC) m 30
431629 AU077025 Hs 265827 TM=M,SS=Y interferon, alpha- ducible protein 30
432302 AA345857 Hs 274307 TIG,TM=M,SS=N KIAA1442 protein 30
442549 AI751601 Hs 8375 MATH,zf-TRAF,zf-C3HC4,TM= TNF rxeptor-associated fxtor 4 30
437959 AI472068 Hs 375604 elF5 elF2B,W2,TM=M,SS=N KIAA1856 protein 30
447400 AK000322 Hs 18457 zf-C3HC4,TM=Y,SS=M hypothetical protein FU20315 30
411734 AW374954 Hs 71779 Homo sapiens DNA from chromosome 19 30
443547 AW271273 Hs 356487 fn3,none hypothetical protein FU 12666 30
417000 BE277919 Hε 306019 TM=Y,SS=M ESTs, Weakly similar to ALU7 HUMAN 30
416987 D86957 Hs 80712 GTP CDC,TM=N,SS=M KIAA0202 protein 30
424494 U78575 Hs 149255 PIP5K,TM=N,SS=M phosphatιdylmosιtol4-phoεphate 5- 30
414496 W73853 Hs 355424 pkιnaεe,F5 F8 type_C,adh ESTε 30
413336 AI569936 Hs 296178 Occludιπ,TM=M,SS=N hypothetical protein FU22637 30
434314 BE392921 Hs 3797 ras,arf,TM=M,SS=N RAB26, member RAS oncogene family 30
401038 TM=M,SS=N C11000425 gι|4507721|ref|NP_003310 30
418245 AA088767 Hs 83883 TM=Y,SS=M tranεmembrane, prostate androgen in 30
407688 W25317 Hε 37616 Human D9 splice vaπant B mRNA, com 30
456906 AF117646 Hs 156637 zf-C3HC4,Cbl N.Cbl N2,Cbl Cas-Br-M ( uπne) ectropic retrovir 30
424744 AW175781 Hs 152720 TM=M,SS=N M-phase phosphopratem 6 30
452195 AA994712 Hs 116878 ESTε 30
415988 BE407713 Hs 78943 Pept C1-lιke,TM=N,SS=M bleomycin hydralase 30
418399 AF131781 Hs 84753 TM=N,SS=N hypothetical protein FU12442 30
420568 F09247 Hs 247735 cadheπn,lιpocaIιn,TM=M,S protocadhenn alpha 10 30
404661 TM=M,SS=N C9000306* gι|12737280|refiXP_006682 30
414152 NMJ03248 Hs 75774 EGF,TSPN,tsp_3,TM=M,SS=M thrombospondiπ 4 30
421307 BE539976 Hs 103305 chramo Homo sapiens mRNA, cDNA DKFZp434B04 30
444868 BE560471 Hs 12101 TM=N,SS=M hypothetical protein 30 450214 BE439763 Hs 227571 RGSTM=M,SS=N regulator of G-protein signalling 4 30
452664 AA398859 Hs 18397 TM=M,SS=M hypothetical protein FU23221 30
422105 AI929700 Hs 111680 TM=M,SS=N endosulfine alpha 30
422278 AF072873 Hs 114218 Fz,Fπzzled,7tm_2,TM=Y,SS fπzzled (Drasophila) homolog 6 30
434067 H18913 Hs 124023 Homo sapienε cDNA FLJ14218 fiε, clo 30
412676 NM 000165 Hs 74471 connexιn,Connexιn43,TM=Y, gap junction protein, alpha 1, 43kD 30
426801 AA486846 Hs 271795 ESTs, Weakly similar to I38022 hypo 30
421983 AI252640 Hs 110364 pro isomerase.πone peptidylprolyl isomeraεe C (cycloph 30
429299 AI620463 Hs 347408 TM=Y,SS=N hypothetical protein MGC13102 30
408912 ' AB011084 Hs 48924 Armadιllo_seg,TM=M,SS=M KIAA0512 gene product, ALEX2 30
438746 AI885815 Hs 184727 transfemπ,Guanylate_kιn Human melanoma-associated antigen p 30
TABLE 4B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT Number Accession
418344 245371 1 AA216387 T63548AA228676
412703 1243670J AW984759 AW984744
434241 63414 AF119913 AI207698 R57074
422940 58443 BC012771 BG397153 BF366196 AA337277 AA319285 AW843252
456034 685586 1 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
434433 111338 1 AA633408 AW749955 AW629759 AI651005
TABLE 4C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) πumberε "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22" Dunham I etal , Nature (1999) 402489495
Strand Indicates DNA strand from which exons were predicted Nt_posιtιon Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
406387 9256180 Plus 116229-116371,117512-117651
400496 9743564 Plus 41515-41695
402496 9797769 Minus 8615-9103
403439 9719679 Plus 91463-91632
401038 7232177 Minus 4277 4469
404661 9797073 Plus 33374-33675,33769-34008
TABLE 5A ABOUT 231 GENES UP-REGULATED IN BREAST CANCER COMPARED TO NORMAL ADULT TISSUES THAT MAY ENCODE EITHER ENZYMES OR PROTEINS AMENABLE TO MODULATION BY SMALL MOLECULES, PEPTIDES, OR ANTIBODIES
Pkey Unique Eos probeset identifier number
ExAccn Exemplar xcesεion number, GenBank xcession number
UniGenelD UniGene number
Pred ProtDomams Certain predicted protein domains Abbreviations uεed TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain, =N, less likely to contain All other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280)
UniGene Title UniGene gene title R1 Ratio of 90th percentite tumor to 50th percentite of normal body tissue
Pkey ExAccn UniGenelD Pred Prot Domains UniGeneTitle R1
409340 BE174629 Hs 321130 aa_permeases,pyπdoxal_de melanophιlιπ (MLPH), mRNA 205
421481 AW3gi972 Hs 104696 TM=M,SS=M KIAA1324 protein 163
419693 AA133749 Hs 301350 ATP1G1 PLM MAT8,TM=Y,SS=M FXYD domain-containing ion transpor 137
417389 BE260964 Hs 82045 PTN_MK,TM=M,SS=Y midkine (neuπte growth-promoting f 137
414521 D28124 Hε 76307 DAN,TM=M,SS=M neurablastoma, suppression of tumor (DAN) 137
438091 AW373062 Hs 351546 hormone rec,zf-C4,none nuclear receptor subfamily 1, group 134
413815 AL046341 Hs 75562 pkιnase,F5_F8Jype_C,TM=Y diεcoidin domain receptor family, m 132
439180 AI393742 Hs 199067 Funn lιke,pkιnase,Rxep_ v-erb-b2 avian erythroblastic leuke 132
431441 U81961 Hs 2794 ASC,TM=Y,SS=N sodium channel, nonvoltage-gated 1 125
452547 AA335295 Hs 74120 LEA,TM=M,SS=N adipose spxifio 2 124
452239 AW379378 Hs 356289 protein tyrosine phosphatase, recep 12 1
441384 AA447849 Hs 288660 7tm_3,none retmoie xid induced 3 11 9
419223 X60111 Hs 1244 transmembrane4,TM=Y,SS=M CD9 antigen (p24) 11 7
413859 AW992356 Hs 8364 SAM_PNT,none Homo sapiens pyruvate dehydrogenase 11 5
410687 U24389 Hs 65436 Lysyl_oxιdase,TM=N,SS=M lysyl oxidase-like 1 11 2
422699 BE410590 Hs 119257 SH3,HS1_rep,TM=M,SS=N emsl εequence (mammary tumor and sq 10 1
419452 U33635 Hs 90572 ιg,pkιπase,TM=Y,SS=M PTK7 protein tyrosine kinase 7 9
427378 BE515037 Hs 177556 MAGE,TM=M,SS=N melanoma antigen, family D, 1 99
444784 D12485 Hs 11951 Somatomedιn_B,Endoπucleas xtonucleotide pyrophosphatase/phos 9 9
436972 AA284679 Hs 25640 PMP22_Claudιn,TM=Y,SS=M claudin 3 97
412926 AI879076 Hs 75061 MARCKS,TM=N,SS=M mxrophage myπstoylated alanme-π 95
425280 U31519 Hs 1872 PEPCK,TM=M,SS=N phosphoenolpyruvate carboxykiπase 1 95
432636 AA340864 Hs 278562 PMP22_Claudιn,TM=Y,SS=M claudin 7 94
423778 Y09267 Hs 132821 FMO-lιke,pyr_redox,TM=Y,S flavin containing monooxygenase 2 94
424206 NM_003734 Hs 198241 Cu amιne_oxιd,Cu_amιne_ox amine oxidase, copper containing 3 94
444797 AB018333 Hs 12002 SH3,SAM,TM=M,SS=N KIAA0790 protein 90 402559 AF043329 Hs 173717 PAP2,TM=Y,SS=M PPAP2B Phosphatidic xid phosphat type 2B 90
443932 AW888222 Hs 9973 SH2,WW,PID,none tensin 89
421143 AB024536 Hs 102171 ιg,LRR,LRRNT,LRRCT,TM=M,S immunoglobulin superfamily contami 88
433592 NM 004642 Hs 3436 TM=M,SS=N deleted in oral cancer (mouse, homo 87
410668 BE3797g4 Hs 159651 death,TNFR_c6TM=Y,SS=M hypothetical protein 87
433662 W07162 Hs 150826 ras.ABC tran,arf,TM=M,SS= RAB25 RAB25, member RAS oncogene fa 86
421853 AL117472 Hs 108924 SH3 Sorb,TM=M SS=N SH3-domaιn protein 5 (ponsin) 86
425335 BE394327 Hs 296267 efhaπd,kazal,arf,ras,7tm_ follistatin like 1 85
400290 H18836 Hs 31608 Cys_knot hypothetical protein FU20041 85
438089 W05381 Hs 351546 hormone ec zf-C4,πone nuclear receptor subfamily 1 , group 84
426158 NMJ01982 Hs 199067 Fuπn like.pkinase Rxep_ v-erb-b2 avian erythroblastic leuke 83
447191 NM 014521 Hs 17667 SH3,TM=M SS=N SH3-domaιn binding protein 4 82
439941 AI392640 Hs 18272 Aa ranε,TM=Y,SS=N ammo xid transporter system A1 82
439318 AW837046 Hs 6527 7tm ,CytC asm GPS,TM=Y,S G protein-coupled receptor 56 81
442213 N36110 Hs 305971 sugar tπTM=Y,SS=M solute earner family 2 (facilitate 81
412649 NM 002206 Hs 74369 ιntegπn_A,FG-GAP,TM=M,SS integnn, alpha 7 8 1
448913 AA194422 Hs 22564 rrm.zf RanBP,pkιnase,GST_ myosin VI 8 1
420166 AW732276 Hs 95583 transmembrane4,TM=Y,SS=M transmembrane 4 superfamily member 80
407102 AA007629 Hs 348601 transport_protSWIB,ASC glycerol 3-phosphate dehydrogenase 79
452516 AA058630 Hs 29759 TM=N,SS=M RNA POLYMERASE I AND TRANSCRIPT REL 79
413076 U10564 Hs 75188 pkιnase,TM=M,SS=N weel (S pombe) homolog 79
443604 C03577 Hs 9615 efhand,TM=M,SS=N myosin regulatory light chain 2, sm 77
429002 AW248439 Hs 2340 Armadillo seg,TM=M,SS=N junction plakoglobin 76
432562 BE531048 Hs 278422 zf C2H2,TM=M,SS=N DKFZP586G1122 protein 76
426359 AA376409 Hs 10862 adenylatekmase.none Homo sapiens cDNA FU23313 fis, cl 75
417733 AL048678 Hs 82503 NA NA H sapiens mRNA for 3 UTR of unknown 75
451541 BE279383 Hs 26557 Armadιllo_seg,TM=M,SS=N plakophilm 3 74
443951 F13272 Hs 356835 PMP22_Claudιn,none femtm, light polypeptide 74
409960 BE261944 Hs 355264 hexokmase 1 73
423184 NM 004428 Hs 1624 Ephπn,TM=M,SS=M ephnn A1 73
405121 X04385 Hs 110802 Cyε kπot.TGF beta.vwa vwc von Willebrand fxtor (VWF), mRNA 71
438974 AF089816 Hs 6454 PDZ,TM=N,SS=M chromosome 19 open reading frame 3 71
417771 AA804698 Hs 82547 retinoic xid receptor responder (t 70
424118 BE269041 Hs 140452 peπlιpιn,TM=N,SS=M cargo selection protein (mannoεe 6 70
402705 X67951 Hs 180900 AhpC-TSATM=M,SS=M peroxiredoxin 1 (PRDX1) 70
417115 AW952792 Hs 334612 Sm pkιnase,TM=N,SS=N εmall nuclear πboπucleoprotein pol 70
442572 AI001922 Hs 135121 HSP70 hypothetical protein FU22415 69
447216 R75812 Hs 169248 cytochrome c.NA.NA p75NTR-assocιated cell death exxut 69
422278 AF072873 Hs 114218 Fz,Fπzzled,7tm 2,TM=Y,SS frizzled (Drasophila) homolog 6 69
414657 AA424074 Hs 76780 TM=M,SS=N protein phosphatase 1, regulatory ( 69
447528 AI612027 Hs 76277 TB2 DP1 HVA22,TM=Y,SS=M Homo sapienε, clone MGC 9381, mRNA, 69
436729 BE621807 Hs 351316 TM=Y,SS=M transmembrane 4 superfamily member 69
428013 AF151020 Hs 181444 TM=Y,SS=M hypothetical protein 69
444143 AW747996 Hs 160999 Bel 2 none ESTs, Moderately similar to A56194 68
414443 AU077268 Hs 76144 ig pkιnase,TM=Y,SS=N platelet-deπved growth fxtor rece 67
418751 BE389014 Hs 372548 SH2,none phosphoιπosιtιde-3-kmase, regulato 67
448479 H96115 Hs 21293 UDPGP,TM=M,SS=N UDP-N-xteylglucosamine pyrophospho 66
410552 X66945 Hs 748 ιg,pkιnase,SH2,SH3,C2,PH, fibroblast growth fxtor receptor 1 66
414883 AA926g60 Hs 348669 CKS,TM=N,SS=N CDC28 protein kinase 1 66
417426 NM 002291 Hs 82124 lamιnιn_EGF,lamιnιn_Nterm laminin, beta 1 66
428179 AI127772 Hs 279696 pkιnase,PX,pkιnase_C,TM=N serum/glucocorticoid regulated kina 66
443195 BE148235 Hs 193063 Aa_trans,none Homo sapienε cDNA FU14201 fis, clo 65
424512 X53002 Hs 149846 ιntegπn_B,EGF,TM=Y,SS=M integnn, beta 5 65
421733 AL119671 Hs 1420 ιg,pkιnase,TM=Y,SS=M fibroblast growth factor receptor 3 65
428950 BE311879 Hs 194673 DED,TM=M,SS=N phosphoprotem enπched in astrocyt 65
450172 NM_005864 Hs 24587 SH3,hormoπe3,TM=M,SS=N signal transduction protein (SH3 co 65
416078 AL034349 Hs 79005 protein tyrosine phosphatase, rxep 65
408912 AB011084 Hs 48924 Armadillo seg,TM=M,SS=M KIAA0512 gene product, ALEX2 64
428373 AI751656 Hs 183986 ιg,TM=Y,SS=M poliovirus receptor-related 2 (herp 64
449029 N28989 Hs 22891 aa_permeaεeε,TM=Y,SS=M solute earner family 7 (cationic a 64
406621 X57809 Hs 181125 ιg HSP70,Ppx-GppA,TM=M,SS immunoglobulin lambda locus 64
431629 AU077025 Hs 265827 TM=M,SS=Y interferon, alpha-inducible protein 64
428169 AI928884 Hs 182793 photoRC,UPF0118,TM=Y,SS=N golgi phosphoprotem 2 64
443337 Y07604 Hs 9235 NDK,TM=N,SS=N non-metastatic cells 4, prate exp 64
451292 AB037716 Hs 26204 SH3,TM=M,SS=N KIAA1295 protein 64
425976 C75094 Hs 334514 voltage CLC,TM=Y,SS=M NG22 protein 64
426539 AB011155 Hs 170290 SH3,PDZ,Guanylate_kιn,TM= discs, large (Drasophila) homolog 5 63
417208 S67773 Hs 81665 ιg,pkιnaεe,TM=Y,SS=M v-kit Hardy-Zuckerman 4 feline sarc 63
438278 BE409248 Hs 57988 TFIIS,RNA_PO M_15KD,UPF0 hypothetical protein FU22357sιmιl 63
429455 AI472111 Hs 278694 lectiπ c CD209 antigen 63
431685 AW296135 Hs 267659 CH.DAG PE-bιnd,PH,RhoGEF, vav 3 oncogene 63
445033 AV652402 Hs 72901 ank,TM=N,SS=N cyclm-depeπdent kinase inhibitor 2 63
411756 BE294350 Hs 71891 pkιπase,F5_F8_type_C,TM=Y discoidin domain receptor family, m 63
453902 BE502341 Hs 3402 ESTs 63
418005 AI186220 Hs 83164 Collagen,TSPN,TM=M,SS=M collagen, type XV, alpha 1 62
449924 W30681 Hs 146233 SH3,none Homo sapiens cDNA FU22130fis, cl 62
426520 BE545684 Hs 343566 aa_permeases,pyπdoxal_de KIAA0251 protein 62
453064 R40334 Hs 89463 potassium large conductance calcium 62
448520 AB002367 Hs 21355 pkιnase,DCX,TM=M,SS=N doublecortm and CaM kmase-like 1 62
452683 AI089575 Hε 374574 homeobox.none progesterone membrane binding prate 62
402575 AF043329 Hs 173717 PAP2,TM=Y,SS=M PPAP2B Phoεphatidic xid phosphat type 2B 62
444672 Z95636 Hs 11669 laminin EGFJaminin G EGF laminin, alpha 5 62
450440 AB024334 Hε 25001 14-3-3,TM=M,SS=N tyrosine 3-monooxygenaεe/tryptophan 62 432314 AA533447 Hs 285173 Xlmk.none ESTε 6 1
438564 AA381553 Hs 198253 ιg,MHC_ll_alpha,πone major histocompatibility complex, c 61
444252 R21135 Hs 54985 ESTs 6 1
425184 BE278288 Hs 155048 ιg,TM=Y,SS=M Lutheran blood group (Auberger b an 6 1
431880 X17033 Hs 271986 vwa,ιntegπn_A,FG-GAP,TM= integnn, alpha 2 (CD49B, alpha 2 ε 61
440475 AI348027 Hs 129826 transmembrane4,TM=Y,SS=M hypothetical protein PP1057 6 1
449538 AI559444 Hs 104679 TM=M,SS=M ESTε 60
414496 W73853 Hs 355424 pkιnase,F5 F8 type C.adh ESTs 60
414217 AI309298 Hs 279898 NA.NA Homo sapienε cDNA FU23165 fis, cl 60
445333 BE537641 Hs 44278 ras,arf,TK,TM=N,SS=M hypothetical protein FLJ12538 simil 59
431183 NM 006855 Hs 250696 ER_lumen_recept,TM=M,SS=M KDEL (Lys-Aεp-Glu-Leu) endoplasmic 59
409645 AI142265 Hs 55498 polyprenyl_synt,TM=M,SS=N geranylgeranyl diphosphate synthase 59
412276 BE262621 Hs 73798 MIF,sugar_tr,none mxrophage migration inhibitory fx 59
416137 BE279513 Hs 278607 pkιnase,UBA,ThιF,TM=M,SS= ubiquitin xtivatmg enzyme E1-lιke 59
412969 AI373162 Hs 75103 14-3-3,TM=N,SS=M tyrosine 3-monooxygenase/tryptophan 59
414504 AW069181 Hs 115175 pkιnase,SAM,TM=M,SS=N steπle-alpha motif and leucine zip 59
433573 AF234887 Hs 57652 7tm_2,EGF,cadheπn,lamιnι cadhenn, EGF LAG εeven-pass G-type 59
436415 BE265254 Hs 343258 Peptιdase_M24,Fuπn like, proliferation-associated 2G4, 38kD 59
413900 AW409747 Hs 75612 TPR,PDZ,WW,Guanylate km, streεε-induced-phoεphopratem 1 (Hs 59
441455 AJ271671 Hs 7854 Zιp,TM=Y,SS=M zinc/iron regulated transporter-lik 59
444006 BE395085 Hs 334762 ldl_rxept_a,PKD,MHC l,TM type I transmembrane protein Fn14 58
408269 AW888219 Hs 44077 CH,TM=M,SS=N pan/in, alpha 58
411372 AI147861 Hs 213289 Glyco transf 11,EGF,ldl r low density lipoprotem rxeptor (f 58
450825 AC005954 Hs 25527 PDZ,Guanylate kιn,TM=N,SS tight junction pratem 3 (zona occl 58
456534 X91195 Hs 100623 LIM,PDZ,pkιnase,TM=N,SS=M phospholipase C, beta 3, neighbor p 57
451558 NM 001089 Hs 26630 ABC_tran,SRP54,TM=Y,SS=M ATP-binding cassette, sub-family A 57
446812 AL042279 Hs 16206 pkinase uncharxteπzed hypolhalamus protei 57
424307 AW2933g9 Hs 356377 nuclear rxeptor co-repressor 1 57
405484 XM_093451 TM=N,SS=M C3002124* gι|12737280|ref|XP_006682 57
425367 BE271188 Hs 155975 TM=M,SS=Y protein tyrosine phosphatase, rxep 57
444607 AW405635 Hs 293687 PI-PLC-X,PH,PI-PLC-Y ESTs 57
421456 AW579842 Hs 104557 zf-C2H2,DUF18,efhand,C2,P hypothetical protein FLJ10697 56
412810 M21574 Hs 74615 ιg,pkιnase,DUF11,TM=M,SS= platelet-deπved growth factor rece 56
450334 AF035959 Hs 24879 PAP2,TM=Y,SS=M phosphatidic xid phosphatase type 56
453880 AI803166 Hs 135121 HSP70,none ESTs, Weakly similar to 138022 hypo 56
439578 AW263124 Hs 350547 WD40,TM=M,SS=N nuclear receptor co-repressor HDAC3 56
450954 AI904740 Hs 25691 TM=Y,SS=M receptor (calcitonin) activity modi 56
414555 N98569 Hs 76422 phoslιp,TM=M,SS=Y phospholipase A2, group IIA (platel 56
409963 AA133590 Hs 377830 MBOAT.none calcium/calmodulin-dependent protei 56
450463 AW952018 Hs 201398 C1q,Collagen,TM=M,SS=Y G protein coupled rxeptor interxt 56
425177 AF127577 Hs 155017 TM=N,SS=M nuclear rxeptor interacting protei 55
445496 AB007860 Hs 12802 SH3,ank,PH,ArfGap,TM=M,SS development and differentiation enh 55
428881 BE313077 Hs 93135 rrm ESTs, Weakly similar to ALU2_HUMAN 55
424441 X14850 Hs 147097 hιstone,CBFD_NFYB_HMF,TM= H2A histone family, member X 55
415662 AW972481 Hs 170610 pkmase.πone ESTs, Highly similarto G01887 MEK 55
422105 AI929700 Hs 111680 TM=M,SS=N endosulfine alpha 55
429556 AW139399 Hs 314807 TM=M,SS=N ESTs 55
408056 AA312329 Hs 42331 Ephnn,TM=M,SS=M ephπn-A4 55
425205 NM 005854 Hs 155106 TM=Y,SS=N receptor (calcitonin) activity modi 55
444633 AF111713 Hs 12284 ιg,TM=Y,SS=M junctional adhesion molecule 1 55
431565 AF161470 Hs 260622 TM=Y,SS=N butyrate-induced transcπpt 1 55
429655 U48959 Hs 211582 pkιnase,th3,ιg,none myosin, light polypeptide kinase 55
431886 L77964 Hs 271980 pkιπase,TM=M,SS=N mitogen-activated protein kinase 6 55
453143 AA382234 Hs 356289 serpm;TM=N,SS=M protein tyrosine phosphataεe, rxep 54
451863 AL120634 Hs 331803 cpn60_TCP1 ,E1-E2_ATPase,C ATPaεe, Ca traπεporting, plasma mem 54
422293 X94453 Hs 114366 aldedh,aakιnaεe,TM=M,SS=N pyrrolιne-5-carboxylate synthetase 54
432179 X75208 Hε 2913 EPH_lbd,fn3,pkinase,SAM,T EphB3 54
408048 NM_007203 Hs 42322 Paralemmm,TM=M,SS=N A kinase (PRKA) anchor protein 2 54
448153 Y10805 Hs 20521 NusG,TM=N,SS=M HMT1 (hnRNP methyltransferase, S c 54
421251 Z28913 Hs 102948 LIM,PDZ,TM=N,SS=M enigma (UM domain protein) 54
439039 AI656707 Hs 48713 pkmase.none ESTs 54
409882 AJ243191 Hs 56874 HSP20,TM=N,SS=M heat sh∞k 27kD protein family, mem 54
451295 AI557212 Hs 17132 pkinase.DAG PE-bιnd,pkιna ESTs, Moderately similar to I54374 54
442549 AI751601 Hs 8375 MATH,zf-TRAF,zf-C3HC4,TM= TNF r eptor-assMiated fxtor 4 54
445930 AF05500g Hs 13456 DAGKc,DAGKa,ank,WD40,bZIP Homo sapienε clone 24747 mRNA seque 54
453082 H18835 Hs 31608 ιon_trans,TM=Y,SS=M hypothetical protein FU20041 54
426432 AF001601 Hs 169857 Arylesterase,TM=M,SS=N parxxonase 2 54
415753 U52819 Hs 78781 PDGF,TM=M,SS=M vascular endothelial growth fxtor 54
450778 U81375 Hs 25450 Nucleosιde_tran,TM=Y,SS=M solute camerfamily 29 (nucleosid 54
414739 U83867 Hs 77196 efhand,SH3,spectπn,TM=N, spectnn, alpha, πon-erythrocytic 1 53
421233 AA209534 Hs 284243 transmembrane4,TM=Y,SS=M tetraspan NET-6 protein 53
414774 X02419 Hs 77274 kπngle,trypsιn,planUhι plasminogen xtivator, urokinaεe 53
414368 W70171 Hs 75939 PRK,CoaE,TM=N,SS=N undine monophosphate kinase 53
446051 BE048061 Hs 37054 Ephπn,A deamιn,dsrm,z-al ephnn-A3 53
423619 T48691 Hs 249159 7tm 1,7tm 2,TM=Y,SS=M adrenergic, alpha-2A-, rxeptor 53
440188 AK001812 Hs 7036 ROK,TM=M,SS=N N-Acetylglucosamine kinaεe 53
414135 NM 004419 Hs 2128 Rhodaneεe,DSPc,Y_phosphat dual specificity phosphatase 5 53
444838 AV651680 Hs 208558 ιntegπn_A,FG-GAP,none ESTs 53
447918 A1129320 Hs 115175 pkmase.SAM.none ESTs, Highly sιmιlartoJC5818 gamm 53
405517 AF000g74 Hs 119498 UM,TM=M,SS=N thyroid hormone receptor mter tor 6 53
413588 AA971014 Hs 75432 IMPDH_C,CBS,IMPDH_N,TM=M, IMP (inosine monophosphate) dehydro 52
411089 AA456454 Hs 355702 cell division cycle 2-lιke 1 (PITSL 52
416157 NM 003243 Hs 342874 zona_pellucιda,TM=Y,SS=M transforming growth fxtor, beta re 52 407744 AB020629 Hs 38095 ABC_tran,PRK,TM=Y,SS=M ATP-binding casεette, sub-family A 52
446108 AL036596 Hs 42322 Paraiemmιn,TM=M,SS=N A kinase (PRKA) anchor protein 2 52
422034 AC006486 Hs 333069 Ets,TM=M SS=N Ets2 represεor fxtor 52
417098 AB017365 Hs 173859 Fπzzled,Fz,7tm 2,toxιn 2 fπzzled (Drasophila) homolog 7 52
430526 AF181862 Hs 242407 7tm 3,TM=Y,SS=M G protein-coupled rxeptor, family 52
414176 BE140638 Hs 75794 7tm_1,CRCB,TM=Y,SS=N EDG-2 (endothelial differentiation 52
416710 AI268325 Hs 54890 Peptidase M49,EGF,ιg Neur hypothetical protein FLJ23590 52
417896 AA379770 Hs 82890 DAD,TM=Y,SS=M defender against cell death 1 52
413244 AW955951 Hs 159265 BTB.Pep M12B_propep,Repra kruppel related zinc finger protein 52
421837 AF135168 Hs 108802 AAA cdc48_N,cdc48 2.NB AR N-elhylmaleimide sensitive fxtor 52
429379 NM 014840 Hs 200598 pkιnase,RI01,TM=M,SS=N KIAA0537 gene product 52
429619 AL120751 Hs 211568 eukaryotic translation initiation f 52
437275 AW976035 Hs 292396 Fnzzled.Fz ESTs, Weakly similar to A47582 B-ce 51
421071 AI311238 Hs 104476 TM=Y,SS=M ESTs, Weakly similar to CGHU1E coll 5 1
448581 NM 002709 Hs 21537 protein phosphatase 1, catalytic su 5 1
452568 AA805634 Hs 300870 PI3_PI4_kmase,TM=M,SS=M Homo sapiens mRNA, cDNA DKFZp547M07 51
452069 AB028949 Hs 183994 Metallophos,TM=M SS=N KIAA1026 protein 51
437175 AW968078 Hs 87773 pkmase.pkinaεe C.none protein kinase, cAMP dependent, cat 51
437056 AI147061 spxtππ,SH3,PH,CH gb 0k33a11 s1 Soares_NSF_F8_gW_OT_P 51
450998 BE387614 Hs 25797 rrm,TM=M SS=N splicing factor 3b, subunit 4, 49kD 51
444441 AW613841 Hs 301394 IRK,TM=Y,SS=N hypothetical protein MGC3101 51
448528 BE613248 Hs 172084 PHD,TM=M,SS=N Homo sapiens, clone IMAGE 3627860, 51
452345 AA293279 Hs 29173 DSPc,TM=M,SS=N hypothetical protein FU20515 51
443412 W84893 Hs 9305 angiotens rxeptor like 1 51
412853 M34175 Hs 74626 Adaptin N.AIpha adaptιnC2 adaptor related protein complex 2, 5 1
439866 AA280717 Hs 6727 rrm,NTF2,TM=M,SS=N Raε GTPaεe xtivating protein SH3 d 51
439975 AW328081 Hs 6817 Ham1p_lιke,TM=M,SS=N inosine tnphosphatase (nucleoside 51
435523 T62849 Hs 11090 TM=Y,SS=M membrane spanning 4-domams, subfam 5 1
433423 BE407127 Hs 8997 HSP70,ιg Ppx-GppA,TM=M,SS heat εhock 70kD protein 1 A 5 1
412641 M16660 Hs 74335 HSP90,HATPase c,TM=M,SS=N heat shxk 90kD protein 1 , beta 51
431236 AV656840 Hs 285115 fn3,TM=Y,SS=M interleukin 13 rxeptor, alpha 1 5 1
438552 AJ245820 Hs 6314 type 1 transmembrane rxeptor (seiz 50
422765 AW409701 Hε 1578 BIR,TM=M,SS=N bxuloviral IAP repeat-containing 5 50
427502 AI811865 Hs 7133 TM=M,SS=N Homo εapienε, clone IMAGE 3161564, 50
414166 AW888941 Hs 75789 DEAD.helicase C,rrm,Ndr,C N myc downstream regulated 50
424954 NM_000546 Hs 1846 P53,WD40,IRK,TM=M,SS=N tumor protein p53 (Li-Fraumeni synd 50
422089 AA523172 Hs 103135 REJ,PLAT,PKD,WSC,LRR ESTs, Weakly similarto SFR4_HUMAN 50
426636 BE242634 Hs 2055 ThιF,UBACT,TM=M,SS=N ubiquit -xtivating enzyme E1 (A1S 50
410793 AW581906 Hs 66392 SH3,efhand,C2,PH,RhoGEF,M intersxtin 1 (SH3 domain protein) 50
TABLE 5B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank accession numbers
Pkey CAT Number Acceεεion
437056 428504_3 AW076398 AI147061 AA765223 AA743380 AI803927
TABLE 5C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495
Strand Indicates DNA strand from which exons were predicted N poεition Indicates nucleotide positions of predicted exons
Pkey Ref Strand Nt_posιtιon
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
TABLE 6A 777 GENES UP-REGULATED IN COLON CANCER COMPARED TO NORMAL ADULT TISSUES
Table 6A Iιsts777 genes up-regulated in colon cancer compared to normal adult tisεues These were selxted from 59680 probesets on the Affymetrix/Eos Hu03 GeneChip array such that the ratio of "average" colon cancer to "average" normal adult tissues was greater than or equal to 30 The "average" colon cancer level was set to the 90lh percentile amongst 95 colon cancers The "average" normal adult tisεue level was set to the go* percentile amongst 209 non-malignant tisεues In order to remove gene-spxifie bxkground levelε of non- spxific hybndization, the 1581 percentile value amongst the 209 non malignant tissues was subtrxted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of tumor to normal body tissue Pkey ExAccn UnigenelD Unigene Title R1
447033 AI357412 Hs 157601 ESTs 31 35
400041 AB033025 Hs 50081 KIAA1199 protein 2900
418007 M13509 Hs 83169 matrix metalloprotemase 1 (interstitial 2641
422330 D30783 Hs 115263 epiregulin 2438
428187 AI687303 Hs 285529 G protein-coupled rxeptor 49 2400
428368 BE440042 Hs 83326 matnx metalloproteinase 3 (stromelysin 2355
422056 BE545072 Hs 122579 hypothetical protein FLJ10461 2270
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient, yeast, h 21 60
444783 AK001468 Hs 62180 anillin (Drasophila Scraps homolog), xt 21 15
415989 AI267700 Hs 317584 ESTs 2095
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph 1935
441031 AI110684 Hs 7645 fibππogeπ, B beta polypeptide 1868
421470 R27496 Hs 1378 annexm A3 1805
439759 AL359055 Hs 67709 Homo sapiens mRNA full length insert cDN 1730
449032 AA045573 Hs 22900 nuclear fxtor (erythroid-deπved 2) lik 17 15
450531 AW301032 Hε 203800 ESTs 1660
432867 AW016936 Hs 233364 ESTs 1635
443211 AI128388 Hs 143655 ESTs 1580
450221 AA328102 Hs 24641 cytoskeleton ass∞iated protein 2 15 10
406964 M21305 gb Human alpha satellite and satellite 3 1500
410355 S58544 Hs 153057 sperm asε∞iated antigen 1 1470
441377 BE218239 Hs 202656 ESTs 1445
413318 AU076607 Hs 75285 inter-alpha (globulin) inhibitor, H2 pol 1435
442409 BE208843 Hs 129544 hypothetical protein MGC15438 1435
440304 BE159984 Hs 125395 ESTs 1425
426427 M86699 Hε 169840 TTK protein kinase 1360
451561 N52812 Hs 177403 ESTs 1280
434032 AW009951 Hs 206892 ESTs 1275
428365 AA295331 Hs 183861 Homo sapiens cDNA FU20042 fis, clone CO 1265
422420 U03398 Hs 1524 tumor necrosis fxtor (ligand) superfami 1255
428664 AK001666 Hs 189095 similar to SALL1 (sal (Drasophila) like 1240
446232 AI281848 Hs 194691 retinoic xid induced 3 1225
424252 AK000520 Hs 143811 hypothetical protein FU20513 12 18
450149 AW960781 Hs 132863 2c family member 2 (odd paired Drosophi 11 85
419752 AA249573 Hs 152618 ESTs, Moderately similar to ZN91JHUMAN Z 11 80
422011 U30246 Hs 110736 solute earner family 12 (sodium/potassi 11 65
452461 N78223 Hs 108106 transcnption fxtor 11 42
431808 M30703 Hs 270833 amphiregulin (εchwannoma-deπved growth 11 35
400534 11 00
448706 AW291005 Hs 21814 interleukin 20 receptor, alpha 1075
453688 AW381270 Hs 194110 hypothetical protein PRO2730 1075
426880 AA393167 Hs 41294 ESTε 1060
408950 AA707814 Hs 14945 long fatty xyl CoA synthetase 2 gene 1055
423020 AA383092 Hs 1608 replication protein A3 (14kD) 1050
453922 AF053306 Hs 36708 budding uninhibited by benzimidazoles 1 1050
447505 AL049266 Hs 18724 Homo sapiens mRNA, cDNA DKFZp564F093 (fr 1040
425761 AW664214 Hs 196729 ESTε 1025
404567 10 15
428536 AI143139 Hs 2288 visimn-like 1 10 10
414972 BE263782 Hs 77695 KIAA0008 gene product 1005
459504 BE514127 gb 601315974F1 NIH_MGC_8 Homo sapiens cD 995
438018 AK001160 Hs 5999 hypothetical pratem FU 10298 990
447863 AL047611 Hs 288885 Homo sapiens cDNA FU14246 fis, clone OV 985
442353 BE3705g4 Hs 49136 ESTε, Moderately similar to ALU7.HUMAN A 985
424905 NM 002497 ' Hs 153704 NIMA (never in mitosis gene a) related k 978
451917 AW391351 Hs 50820 Homo sapiens unknown mRNA 973
420800 AL045633 Hs 44269 ESTs 968
438639 AI278360 Hs 31409 ESTs 955
439521 AI808955 Hs 58248 ESTs 955
445676 AI247763 Hs 16928 ESTs 950
408489 AI082437 Hs 26690 ESTs 950
418738 AW388633 Hs 6682 solute camerfamily 7, (cationic am o 937
446311 AW007284 Hs 149795 ESTs, Moderately similar to ALU1JHUMAN A 900
423349 AF010258 Hs 127428 homeo box A9 896
400195 NA NA 890
411765 H43346 gb yp09a04 r1 Soares breast 3NbHBst Homo 890
418895 AA894638 Hs 14600 ESTs 885
424653 AW977534 Hs 151469 calcium calmodulin-dependent senne prat 880
448776 BE302464 Hs 30057 MRS2 (S cerevisiae) like, magnesium hom 875
417218 AA005247 Hs 285754 met proto-onccgene (hepat∞yte growth fa 865
414559 AV656184 Hs 76452 C-rextive protein, pentraxm related 864
445436 AI224105 Hs 151408 ESTs 850
403776 850
433447 U29195 Hs 3281 neuronal pentraxm II 850
407168 R45175 Hs 117183 ESTs 831
410335 AW960146 Hs 284137 hypothetical protein FU 12888 830
422505 AL120862 Hs 124165 ESTs 825
458242 BE299588 Hs 28465 Homo sapienε cDNA FU21868 fiε, clone H 820
452943 BE247449 Hs 31082 hypothetical protein FU 10525 815
446155 AI553695 Hs 159422 Homo sapiens cDNA FU 13997 fis, clone Y7 810
409687 T51125 Hε 8493 ESTs 805 416661 AA634543 Hs.79440 IGF-II mRNA-bindiπg protein 3 8.00
443614 AV655386 Hs.7645 fibrinogen, B beta polypeptide 7.93
406360 NA NA 7.80
443450 N66045 Hs.133529 ESTs 7.75
414422 AA147224 Hs.337232 ESTs 7.75
442611 BE077155 Hs.177537 hypothetical protein DKFZp761B1514 7.70
438604 AA811896 Hs.44604 ESTs 7.60
447254 NM 004153 Hs.17908 origin rxognition complex, subunit 1 (y 7.55
400250 NA NA , 7.53
420759 T11832 Hs.127797 Homo sapiens cDNA FLJ11381 fis, clone HE 7.50
404996 7.50
450459 AI697193 Hs.299254 Homo sapiens cDNA: FLJ23587 fis, clone L 7.45
445019 AI205540 Hs.281295 ESTs 7.30
409269 AA576953 Hs.22972 hypothetical protein FLJ 13352 7.25
448816 AB033052 Hs.22151 KIAA1226 protein 7.25
444361 W76027 Hs.23920 hypothetical protein FU11105 7.25
449370 AK002114 Hs.23495 hypothetical protein FLJ 11252 7.20
433859 AW896758 Hs.273789 ESTs 7.20
416143 AI955650 Hs.79033 glutaminyl-peptide cyclotransferase (glu 7.20
456120 AA535244 Hs.78305 RAB2, member RAS oncogene family 7.20
419751 AW195581 Hs.93121 KIAA0761 protein 7.16
417830 AW504786 Hs.122579 hypothetical protein FU10461 7.15
456553 AA721325 Hs.189058 ESTs, Highly similar to Similar to a C.e 7.15
421373 AA808229 Hs.167771 ESTs 7.10
418763 AK000219 Hs.88367 hypothetical protein FU20212 7.00
423248 AA380177 Hs.125845 ribulose-5-phosphate-3-epimerase 6.96
444798 BE242144 Hs.12013 ATP-binding cassette, sub-family E (OABP 6.95
429486 AF155827 Hs.203963 hypothetical protein FU 10339 6.95
413573 AI733859 Hs.149089 ESTs 6.95
442660 AW138174 Hs.130651 ESTs 6.93
427878 C05766 Hs.181022 CGI-07 protein 6.90
438394 BE379623 Hs.27693 peptidylprolyl isomerase (cyclophilin)-l 6.85
422711 D60641 Hs.21739 Homo sapiens mRNA; cDNA DKFZp586l1518 (f 6.82
457030 AI301740 Hs.173381 dihydropyrimidinase-like 2 6.80
417168 AL133117 Hs.81376 Homo sapiens mRNA; cDNA DKFZp586L1121 (f 6.80
442973 BE567665 Hs.288550 Homo sapiens cD A: FLJ23156 fis, clone L 6.80
453102 NM 007197 Hs.31664 frizzled (Drasophila) homolog 10 6.75
416018 AW138239 Hs.78977 proprotein convertaεe εubtiliεiπ/kexin t 6.75
424051 AL110203 Hs.138411 Homo εapienε mRNA; cDNA DKFZp586J1922 (f 6.71
401644 6.70
450434 AA166950 Hs.195870 hypothetical protein FLJ14991 6.70
428479 Y00272 Hs.184572 cell diviεion cycle 2, G1.to S and G2 to 6.69
406747 AI925153 Hs.217493 annexin A2 6.65
445191 AF048686 Hs.12393 dTDP-D-glucoεe 4,6-defιydratase 6.60
424296 AI631874 Hs.155140 casein kinase 2, alpha 1 polypeptide 6.60
428392 H10233 Hs.2265 sxretory granule, neuroend∞rine protei 6.55
427072 H38046 Hs.303193 ESTs 6.55
452588 AA889120 Hs.110637 homeo box A10 6.53
439809 R41396 Hs.101774 hypothetical protein FU23045 6.50
423123 NM 012247 Hs.124027 SELENOPHOSPHATE SYNTHETASE ; Human selen 6.50
418454 AA315308 Hs.195870 hypothetical protein FU14991 6.50
423685 BE350494 Hs.49753 uveal autoantigen with coiled coil domai 6.50
447342 AI199268 Hs.19322 Homo sapiens, Similar to RIKEN cDNA 2010 6.50
410908 AA121686 Hs.10592 ESTs 6.47
406671 AA129547 Hs.285754 met proto-oπcogene (hepatocyte growth fa 6.47
450638 AK001826 Hs.25245 hypothetical protein FU11269 6.45
452838 U65011 Hs.30743 preferentially expressed antigen in mela 6.42
451389 N73222 Hs.270009 matrix Gla protein 6.40
438202 AW169287 Hs.22588 ESTs 6.40
452108 AI097560 Hs.61210 ESTs, Weakly similar to I38022 hypotheti 6.40
425860 L29339 Hs.1964 solute camerfamily 5 (sodium/glucose 6.37
435538 AB011540 Hs.4930 low density lipoprotein receptor-related 6.36
436530 AI005457 Hε.275048 ESTs 6.35
417404 NM 007351 ) Hs.82101 plxkstrin homology-like domain, family 6.34
430388 AA356923 Hs.240770 nuclear cap binding protein εubunit 2, 2 6.32
425905 AB032959 Hs.318584 novel C3HC4 type Zinc finger (ring tinge 6.31
407237 AA169872 Hs.6216 Homo εapiens hepatoceilular carcinoma-as 6.30
413597 AW302885 Hs.117183 ESTs 6.30
429529 AA454190 Hs.24283 ESTs, Moderately similarto reduced expr 6.30
409916 BE313625 Hs.57435 solute camerfamily 11 (proton-coupled 6.25
407746 AK001962 Hs.38114 hypothetical protein FU11100 6.20
426921 AA037145 Hs.172865 cleavage stimulation fxtor, 3' pre-RNA, 6.20
438050 BE262816 Hs.6061 protein kinase, AMP-xtivated, beta 1 no 6.20
416857 AA188775 Hs.202453 ESTs 6.20
409683 U33317 Hs.711 defensiπ, alpha 6, Paπeth cell-specific 6.18
452291 AF015582 Hs.28853 CDC7 (cell diviεion cycle 7, S. cerevisi 6.15
420096 AA775910 Hs.95011 syntrophiπ, beta 1 (dystrophin-aεε∞iate 6.15
448693 AW004854 Hs.228320 hypothetical protein FU23537 6.15
433393 AF038564 Hs.98074 itchy (mouse homolog) E3 ubiquitin prate 6.11
424745 AA214618 Hs.152750 xtivator of S phase kinase 6.10
408771 AW732573 Hε.47584 potassium voltage-gated channel, delayed 6.10
454438 AA224053 Hs.172405 cell division cycle 27 6.08
407771 AL138272 Hs.62713 ESTs 6.08 416057 AI927382 Hs.29857 ESTs 6.05
442917 AA314907 Hs.85950 ESTs 6.00
451813 NM_016117 Hs.27182 phospholipase A2-xtivatiπg protein 6.00
453700 AB009426 Hs.560 apolipoprotein B mRNA editing enzyme, ca 5.96
412246 AI160873 Hs.69233 zinc finger protein 5.96
430899 BE018217 Hs.183528 hypothetical protein FU14906 5.95
418668 AW407987 Hs.173518 M-phase phosphoprotein homolog 5.95
416421 AA134006 Hs.79306 eukaryotic translation initiation fxtor 5.95
455800 R22479 Hs.167073 Homo sapiens cDNA FU 13047 fis, clone NT 5.90
409913 BE243842 Hs.283077 centrosomal P4.1-associated protein; unc 5.90
429201 X03178 Hs.198246 group-spxific component (vitamin D bind 5.87
408908 BE296227 Hs.250822 serine/threonine kinase 15 5.86
413585 AI133452 Hs.75431 fibrinogen, gamma polypeptide 5.86
432298 AL118812 Hs.274293 Homo εapiens mRNA; cDNA DKFZp761 G1111 (f 5.85
424345 AK001380 Hs.145479 Homo sapiens cDNA FU10518 fis, clone NT 5.85
441645 AI222279 Hs.201555 ESTs, Weakly similar to T23406 hypotheti 5.85
409187 AF154830 Hs.50966 carbamoyl-phosphate synthetase 1, mit∞h 5.85
406687 M31126 Hs.272620 pregnancy spxific beta-1-glycoprotein 9 5.85
452281 T93500 Hs.28792 Homo sapiens cDNA FU11041 fis, clone PL 5.82
429g45 NM 006729 Hs.226483 diaphanous (Drasophila, homolog) 2 5.80
459309 AA040620 Hs.5672 hypothetical protein AF140225 5.80
410060 NM 001448 Hs.58367 glypican 4 5.79
423806 AA331247 Hs.86617 ESTs 5.77
454036 AA374756 Hs.93560 Homo sapiens mRNA for KIAA1771 protein, 5.75
430345 AK000282 Hs.239681 hypothetical protein FU20275 5.75
411096 U80034 Hs.68583 mitochondrial intermediate peptidase 5.75
429125 AA446854 Hs.271004 ESTs, Weakly similarto I38022 hypotheti 5.75
442957 AI949952 Hs.49397 ESTs 5.75
426642 AW068223 Hs.171581 ubiquitin C-terminal hydrolase UCH37 5.70
426518 Z43039 Hs.170198 KIAA0009 gene product 5.70
441894 AA134329 Hs.24170 Homo sapiens, clone IMAGE:3685398, mRNA, 5.70
415385 R17798 Hs.7535 COBW-like protein 5.70
409757 NM_001898 Hs.123114 cystatin SN 5.69
433687 AA743991 gb:ny57g01.s1 NCI_CGAP_Pr18 Homo sapiens 5.68
424492 AI133482 gb:HA2093 Human fetal liver cDNA library 5.60
452606 N45202 Hs.90012 hypothetical protein FU23441 5.60
438777 AA825487 Hs.142179 ESTs 5.60
417235 AA810278 Hs.24250 ESTs 5.60
451177 AI969716 Hs.13034 ESTs 5.60
415227 AW821113 Hs.72402 ESTε 5.58
436217 T53925 Hs.107 fibrinogen-like 1 5.56
452881 AW135220 Hs.241021 ESTs 5.55
426010 AA136563 Hs.1975 hypothetical protein FU21007 5.55
426235 AI631964 Hs.34447 ESTs 5.55
445640 AW969626 Hs.31704 ESTs, Weakly similar to KIAA0227 [H.sapi 5.53
444743 AA045648 Hs.301057 nudix (nucleoside diphosphate linked moi 5.52
442880 AA857025 Hs.8878 kineεin-like 1 5.50
418882 NM_004996 i Hε.89433 ATP-binding cassette, sub-family C (CFTR 5.50
453884 AA355925 Hs.36232 KIAA0186 gene product 5.47
444478 W07318 Hs.240 M-phase phosphoprotein 1 5.47
419502 AU076704 Hε.90765 fibrinogen, A alpha polypeptide 5.47
420218 AW858037 Hs.286 ribosomal protein L4 5.45
421155 H87879 Hs.102267 lysyl oxidase 5.45
441421 AA356792 Hs.334824 hypothetical protein FU14825 5.45
456435 AI880384 Hs.270747 ESTs, Weakly similar to ALU2_HUMAN ALU S 5.45
428046 AW812795 Hs.155381 ESTs, Moderately similar to I38022 hypot 5.44
446372 AB020644 Hs.14945 long fatty xyl-CoA synthetase 2 gene 5.42
421477 AI904743 Hs.104650 hypothetical protein FU 10292 - 5.41
409564 AA045857 Hs.54943 frxture callus 1 (rat) homolog 5.41
453080 AI423056 Hs.23921 hypothetical protein DKFZp547A023 5.35
430217 N47863 Hs.336901 ribosomal protein S24 5.33
417372 T99755 Hs.334728 ESTs 5.30
415139 AW975942 Hs.48524 ESTs 5.30
412140 AA219691 Hs.73625 RAB6 interacting, kinesin-like (rabkines 5.29
424086 AI351010 Hs.102267 lysyl oxidase 5.27
409327 L41162 Hs.53563 collagen, type IX, alpha 3 5.27
417576 AA339449 Hs.82285 phosphoribosylglycinamide formyltranεfer 5.26
452131 AI860677 Hs.72325 Human DNA sequence from clone RP1-187J11 5.25
436016 AA806465 Hs.121536 Human DNA sequence from clone RP11472E5 5.25
449347 AV649748 Hs.295901 KIAA0493 protein 5.25
445038 AI635444 Hε.143917 dJ467N11.1 protein 5.25
453921 AI824009 Hs.44577 ESTs 5.25
413582 AW295647 Hs.71331 hypothetical protein MGC5350 5.25
421076 AW007988 Hs.23329g ESTs, Weakly similar to I38022 hypotheti 5.25
407884 BE075316 Hs.g5011 syntrophin, beta 1 (dyεtrophin-associate 5.24
433384 AI021992 Hε.124244 ESTs 5.23
422026 U80736 Hs.110826 trinucleotide repeat containing 9 5.21
447020 T27308 Hs.16986 hypothetical protein FU11046 5.20
441795 N58115 Hs.21137 AD024 protein 5.20
449416 AI651016 Hs.246311 ESTs 5.20
418379 AA218940 Hs.137516 i fidgetin-like 1 5.20
426753 T89832 Hε.170278 : ESTs 5.18
422109 S73265 Hs.1473 gastrin-releasing peptide 5.17 424085 NMJ02914 Hs.139226 replication factor C(xtivator 1) 2 (40 5.17
416806 NM_000288 Hs.79993 peroxisomal biogenesis factor 7 5.17
424717 H03754 Hs.152213 wingless-type MMTV integration site fami 5.15
427728 AJ245600 Hs.180545 Homo sapiens mRNA for hypothetical prate 5.15
5 447713 AI420733 Hs.207083 ESTs 5.15
425739 T19016 Hs.159410 molybdopterin synthase sulfurylase 5.15
420170 U43374 Hs.95631 Human normal keratinocyte mRNA 5.15
407244 M10014 Hs.75431 fibrinogen, gamma polypeptide 5.13
441139 AW449009 Hs.126647 ESTs 5.13
10 451121 AW973795 Hs.128927 Homo sapiens CDNA FU13903 fis, clone TH 5.10
435202 AI971313 Hs.170204 KIAA0551 protein 5.10
431699 NM 001173 Hs.267831 Rho GTPaεe xtivating protein 5 5.10
418384 AW149266 Hs.25130 Homo sapiens CDNA FU14923 fis, clone PL 5.09
422805 AA436989 Hs.121017 H2A histone family, member A 5.07
15 411750 BE562298 Hs.71827 KIAA0112protein; homolog ofyeastribos 5.06
435496 AW840171 Hs.265398 ESTs, Weakly similar to transformation-r 5.06
434539 AW748078 Hs.214410 ESTs, Weakly similarto MUC2_HUMAN MUCIN 5.05
413293 AL047483 Hs.302498 GTP-biπdiπg protein homologous to Saccha 5.05
445236 AK001676 Hs.12457 hypothetical protein FU10814 5.05
20 415091 AL044872 Hs.77910 3-hydroxy-3-methylg!utaryl-Coenzyme A sy 5.05
441675 A1914329 Hs.5461 ESTs 5.00
440802 AW901804 Hs.23984 hypothetical protein FU20147 5.00
401480 NA NA 5.00
_ _ 408562 AI436323 Hε.31141 Homo sapiens mRNA for KIAA1568 protein, 4.95
25 426269 H15302 Hs.168950 Homo sapiens mRNA; cDNA DKFZp566A1046 (f 4.92
414718 H95348 Hs.107987 ESTs 4.91
419139 AI123517 Hs.269940 ESTs 4.90
430789 AA632577 Hs.310235 ESTs, Weakly similar to I78885 serine/th 4.80
425420 BE536911 Hs.234545 hypothetical protein NUF2R 4.90
30 408758 NMJ03686 Hs.47504 exoπuclease l 4.90
439741 BE379646 Hs.6904 Homo sapiens mRNA full length insert cDN 4.00
418612 AB037788 Hs.224961 cleavage and polyadenylation εpxific fa 4.90
433927 AI557019 Hs.116467 small nuclear protein PRAC 4.89
450568 AL050078 Hs.25159 Homo sapienε cDNAFUI 0784 fis, clone NT 4.88
35 455777 AA524285 Hs.154172 ESTs, Moderately similar to BCGF_HUMAN B 4.87
428743 AL080060 Hs.301549 Homo sapiens mRNA; cDNADKFZp564H172 (fr 4.87
421126 M74587 Hs.102122 insulin-like growth fxtor binding prate 4.86
411835 U29343 Hs.72550 hyaluranaπ-mediated motility receptor (R 4.85
418396 AI765805 Hs.26691 ESTs 4.85
40 430510 AW162916 Hs.241576 hypothetical protein PR02577 4.84
408430 S79876 Hs.44926 dipeptidylpeptidase IV (CD26, adenosine 4.80
406414 4.75
430178 AW449612 Hs.152475 ESTs 4.71
411901 AA166730 Hs.6966 Human DNA εequence from clone RP1-187J11 4.70
45 404025 NA NA 4.70
451807 W52854 Hs.27099 hypothetical protein FU23293 similar to 4.68
436662 AI582393 Hs.126695 ESTs 4.68
414140 AA281279 Hs.23317 hypothetical protein FU14681 4.68
410044 BE566742 Hs.58169 highly expreεεed in cancer, rich in leuc 4.65
50 431041 AA490967 Hs.197g55 KIAA0704 protein 4.65
417860 AW408557 Hs.235498 hypothetical protein FU 14075 4.65
410658 AW105231 Hε.192035 ESTs 4.65
425895 AI269484 Hs.161427 zinc finger protein 215 4.65
_ _ 422892 AA988176 Hs.121553 hypothetical protein FU20641 4.65
55 436397 AA715013 Hs.169835 ESTs 4.60
430225 AA192669 Hs.45032 ESTs 4.60
423197 T91418 Hs.125156 transcriptional adaptor 2 (ADA2, yeast, 4.60
413374 NM_001034 Hs.75319 ribonucleotide reductase M2 polypeptide 4.60
412723 AA648459 Hs.335951 hypothetical protein AF301222 4.59
60 425745 U44060 Hs.14427 Homo sapienε cDNA: FU21800 fis, clone H 4.59
452795 AW392555 Hs.18878 hypothetical protein FU21620 4.58
430704 AW813091 Hs.335799 ESTs 4.56
429682 NM_006306 Hs.211602 SMC1 (structural maintenance of chromoso 4.55
433326 AI379486 Hs.159430 ESTs 4.55
65 437958 BE139550 Hs.121668 ESTs, Moderately similar to PC4259 ferri 4.55
410566 AA373210 Hs.43047 Homo sapiens CDNA FU13585 fis, clone PL 4.55
423343 AA324643 Hs.246106 ESTs 4.55
416467 H57585 Hs.37467 ESTε 4.55
408867 AA437199 Hs.656 cell division cycle 25C 4.54
70 419423 D26488 Hs.90315 KIAA0007 protein 4.54
414132 AI801235 Hs.48480 ESTs 4.53 423948 AW392342 Hs.283077 centrosomal P4.1-assxiated protein; unc • 4.53
425746 NM 001701 Hs.159440 bile xid Coenzy e A: amino xid N-xylt 4.50
451009 AA013140 Hs.115707 ESTs 4.50
75 431064 AI903735 gb:MR-BT035-200199-031 BT035 Homo sapien 4.50
432725 AL137496 Hs.9001 ESTs 4.50
400298 AA032279 Hs.61635 six transmembrane epithelial antigen of 4.50
410486 AW235094 Hs.69233 zinc finger protein 4.50
428532 AF157326 Hs.184786 TBP-iπterxting protein 4.50
80 420782 NM_005754 Hs.220688 Ras-GTPase-xtivatiπg protein SH3-domain 4.50
408380 AF123050 Hs.44532 diubiquitin 4. g
423g36 U7762g Hs.135639 xhaete-εcute complex (Drasophila) homol 4.47
434294 AJ271379 Hs.76194 ribosomal protein S5 4.47 442875 BE623003 Hε.23625 Homo sapiens clone TCCCTA00142 mRNA sequ 4.46
447102 BE167434 Hs.98471 ESTs, Weakly similar to T18712 hypotheti 4.45
410142 AA081924 Hs.124918 KIAA1785 protein 4.45
434884 AW977850 Hs.23856 hypothetical protein MGC5297 4.45
420002 AA814043 Hs.88045 ESTs 4.45
400115 NA NA 4.45
430967 H16791 Hs.31445 ESTs 4.41
438078 AI016377 Hs.131693 ESTs 4.41
412359 AW837985 gb:QV3-LT0048-140200-083-e05 LT0048 Homo 4.40
429774 AI522215 Hs.50883 KIAA1804 protein 4.40
426214 H59846 Hs.128355 ESTs, Moderately similar to ALU7_HUMAN A 4.40
419790 U79250 Hs.93201 glycerol-3-phosphate dehydrogenase 2 (mi 4.40
450480 X82125 Hs.25040 zinc finger protein 239 4.40
421211 AA284966 Hs.266308 mosaic serine protease 4.40
419261 X07876 Hs.89791 wingless-type MMTV integration site fami 4.40
434414 AI798376 gb:tr34b07.x1 NCI_CGAP_Ov23 Homo sapienε 4.37
448305 AA625207 Hs.264915 Homo sapiens cDNA FU 12808 fis, clone NT 4.35
410568 AW162948 Hs.64542 cleavage and polyadenylation specific fa 4.35
459574 AI741122 Hs.101810 Homo sapienε cDNA FU 14232 fis, clone NT 4.35
448243 AW369771 Hs.52620 integπn, beta 8 4.35
438069 N80701 Hs.33790 ESTs 4.35
446152 AI292036 Hs.150028 ESTs 4.34
439580 AF086401 Hs.203847 ESTs, Moderately similar to S65657 alpha 4.32
436211 AK001581 Hs.334828 hypothetical protein FU10719; KIAA1794 4.30
452401 NM 007115 Hs.29352 tumor nxrosis fxtor, alpha-induced pro 4.30
422835 BE218705 Hs.121378 metallothionein-like 5, testis-specifϊc 4.30
418845 AA852985 Hs.89232 chromobox homolog 5 (Drasophila HP1 alph 4.30
439619 AW975998 Hε.58595 ESTs, Weakly similar to I38022 hypotheti 4.30
458076 R80061 Hs.164478 hypothetical protein FU21939 similar to 4.30
450192 AA263143 Hs.245g6 RAD51-interxting protein 4.29
443232 AF161521 Hs.g081 phenylalanyl-tRNA synthetase beta-subuni 4.28
413881 L00190 Hs.75599 serine (or cysteine) proteinase inhibito 4.26
434217 AW014795 Hs.23349 ESTs 4.26
409723 AW885757 Hs.257862 ESTs 4.25
417956 AA210704 Hs.190465 ESTs 4.25
458433 AL135352 Hs.255883 ESTs, Weakly similar to I38022 hypotheti 4.25
409928 AL137163 Hs.57549 hypothetical protein dJ473B4 4.24
447400 AK000322 Hs.18457 hypothetical protein FU20315 4.22
424583 AF017445 Hs.150926 fucose-1-phosphateguanylyltransferase 4.20
429436 AA452934 Hs.279813 hypothetical protein 4.20
424625 AW904466 Hs.321197 PDZ domain protein (Drasophila inaD-like 4.20
448912 D83781 Hs.22559 KIAA0197 protein 4.20
442671 AI005668 Hs.134779 EST 4.20
411893 R82845 Hs.273789 ESTs 4.20
456281 AA284166 Hε.84113 cyclin-dependent kinase inhibitor 3 (CDK 4.20
421106 AA877124 Hs.172844 ESTs 4.20
451401 AI793163 gb:on52g03.y5 NCI CGAP_Co8 Homo sapiens 4.20
404516 NA NA 4.20
414968 C16096 Hs.22826 tropomodulin 3 (ubiquitous) 4.20
421308 AA687322 Hε.ig2843 leucine zipper protein FKSG14 4.20
419229 AI827237 Hs.282884 ESTs 4.18
412104 AW205197 Hs.240851 Homo sapiens, Similar to RIKEN cDNA 2210 4.16
453911 AW503857 Hε.4007 Sarcolemmal-ass∞iated protein 4.16
433159 AB035898 Hs.150587 kinesin-like protein 2 4.15
419247 S65781 Hs.89764 fragile X mental retardation 1 4.15
432491 AA662910 Hs.42635 hypothetical protein DKFZp434K2435 4.15
422093 AF151852 Hs.111449 CGI-94 protein 4.15
428692 AI372822 Hs.110103 RNA poly eraεe I transcription fxtor RR 4.15
446999 AA151520 Hs.334822 hypothetical protein MGC4485 4.15
414538 AW612228 Hs.107987 ESTs 4.14
453931 AL121278 Hs.25144 ESTs 4.12
427718 AI798680 Hs.25933 ESTs 4.11
453863 X02544 Hs.572 orosomucoid 1 4.10
440209 H05049 Hε.22269 neurexin 3 4.10
435148 AI918049 Hs.124961 ESTs 4.10
409732 NM 01612; > Hs.56148 NY-REN-58 antigen 4.10
448692 AW013907 Hs.167531 methylcrotonoyl-Coenzyme A carboxylase 2 4.10
428301 AW628666 Hs.98440 ESTs, Weakly similar to I38022 hypotheti 4.10
444188 AI393165 Hs.699 peptidylpralyl isomerase B (cyclophilin 4.10
457059 BE561665 Hs.177677 exosome component Rrp40 4.10
407162 N63855 Hs.142634 zinc finger protein 4.10
406117 4.10
434370 AF130988 Hs.58346 xtodysplasin 1, anhidrotio rxeptor 4.09
427651 AW405731 Hs.18498 Homo sapiens cDNA FU12277 fis, clone MA 4.08
448666 NM 014953 Hs.323346 KIAA1008 protein 4.07
450375 AA009647 Hs.8850 a disintegnn and metalloprateinase doma 4.07
410467 AF102546 Hs.63931 dxhshund (Drasophila) homolog 4.07
456030 AA136106 Hs.184852 KIAA1553 protein 4.05
434082 AI373481 Hs.131715 hypothetical protein PR01777 4.05
443646 AI085198 Hs.164226 ESTs 4.05
434265 AA846811 Hs.130554 Homo sapiens cDNA: FLJ23089 fis, clone L 4.05
418524 AA300576 Hε.85769 xidic 82 kDa protein mRNA 4.05
432619 AW291722 Hε.278526 related to the N terminus of tre 4.05 447207 AA442233 Hs.17731 hypotheUcal protein FU12892 4.05
423673 BE003054 Hs.1695 matrix metaltoproteinase 12 (mxrophage 4.04
414853 U31116 Hs.77501 sarcoglycan, beta (43kD dyεtrophin-ass∞ 4.04
424176 AL137273 Hs.142307 hypothetical protein 4.04
452259 AA317439 Hs.28707 signal sequence rxeptor, gamma (translo 4.04
418203 X54942 Hs.83758 CDC28 protein kinase 2 4.03
435420 AI928513 Hs.59203 ESTs 4.03
406666 V00495 Hs.184411 albumin 4.02
417655 AA780791 Hs.14014 hypothetical protein FLJ14813 4.00
449448 D60730 Hε.57471 ESTs 4.00
421037 AI684808 Hs.197653 ESTs 4.00
448310 AI480316 gb:tm26h09.x1 Soares_NFL_T_GBC_S1 Homo s 4.00
408155 AB014528 Hs.43133 KIAA0628 gene product 4.00
413841 M34276 Hs.75576 plasminogen 3.98
400110 NA NA 3.98
400289 X07820 Hε.2258 matrix metaltoproteinase 10 (stromelyεin 3.97
443715 AI583187 Hs.9700 cyclin E1 3.97
408296 AL117452 Hs.44155 DKFZP586G1517 protein 3.97
450164 A1239923 Hε.30098 ESTε 3.97
451592 AI805416 Hs.213897 ESTε 3.95
402373 AL135225 Hs.301865 dopxhrome tautomerase (dopxhrome delta 3.95
426199 AA371865 Hs.07090 ESTs 3.95
414148 BE084049 gb;PM0-BT0651-270400-003-f02 BT0651 Homo 3.95
417006 AW673606 Hs.80758 aspartyl-tRNA synthetase 3.94
449532 W74653 Hε.271593 ESTs, Moderately similar to A47582 B-cel 3.93
434551 BE387162 Hε.280858 ESTs, Highly similar to A35661 DNA excis 3.93
436291 BE568452 Hs.5101 protein regulator of cytokinesis 1 3.92
423337 NM_004655 Hs.127337 axin 2 (conductin, axil) 3.91
416185 AW975861 Hs.47367 KIAA1785 protein 3.91
443054 AI745185 Hs.8839 yes-aεεxiated protein 65 kDa 3.90
432596 AJ224741 Hs.278461 matrilin 3 ' 3.90
451229 AW967707 Hs.48473 ESTs 3.90
413583 AL120806 Hs.5888 ESTs 3.90
432702 AW973g53 Hε.293744 ESTs 3.90
437207 T27503 Hs.15929 hypothetical protein FU12910 3.90
434699 AA643687 Hs.149425 Homo sapiens cDNA FU11980 fis, clone HE 3.90
4236g7 BE088697 Hs.131834 Homo sapiens mRNA; cDNA DKFZp434B0328 (f 3.90
428822 W28418 Hs.30715 potassium voltage-gated channel, Isk-rel 3.90
432289 AI860145 Hs.55118 ESTs 3.89
413384 NM 000401 Hs.75334 exostoses (multiple) 2 3.88
414136 AA812434 Hs.118023 SMC2 (structural maintenance of chromoso 3.88
433042 AW193534 Hs.281895 Homo εapieπs cDNA FU11660 fis, clone HE 3.88
410094 BE147897 Hs.58593 general transcription fxtor IIF, polype 3.88
441826 AW503603 Hs.129915 phosphotriesterase related 3.87
444059 R69743 Hs.116774 integnn, alpha 1 3.86
426262 AI792141 Hε.196270 folate transporter/carrier 3.85
452641 AW9528g3 Hs.237825 signal recognition particle 72kD 3.85
454403 BE065985 gb:RC3-BT0319-120200-014-a09 BT0319 Homo 3.85
448315 AW290912 Hs.20797 ESTs, Weakly similar to ALU1_HUMAN ALU S 3.85
411343 U77949 Hs.69563 CDC6 (cell division cycle 6, S. cerevisi 3.85
409734 BE161664 Hs.56155 hypothetical protein 3.85
454014 AW016670 Hs.233275 ESTε 3.84
453116 AI276680 Hs.146086 ESTs 3.83
449508 AK001566 Hs.23618 hypothetical protein FU 10704 3.82
428227 AA321649 Hs.2248 small inducible cytokine subfamily B (Cy 3.82
435040 AI932350 Hs.152825 ESTs 3.81
426249 F05422 Hs.168352 nucleoporin-like protein 1 3.81
451110 AI955040 Hs.265398 ESTs, Weakly similar to transformation-r 3.81
431716 D89053 Hs.268012 fatty-xid-Coenzyme A ligase, long-chain 3.81
437631 AA764749 Hs.267245 hypothetical protein FU14803 3.80
429118 H20669 Hs.35406 ESTs, Highly similar to unnamed protein 3.80
405760 3.80
438295 AI394151 Hs.37932 ESTs 3.80
453628 AW243307 Hs.83937 hypothetical protein 3.80
450096 AI682088 Hs.79375 hol∞arboxylase synthetase (biotin-[prop 3.80
440318 AW236021 Hs.78531 Homo sapiens, Similar to RIKEN cDNA 5730 3.76
423881 AK001720 Hε.134403 hypothetical protein FLJ10858 3.75
408728 AL137378 Hε.47125 hypothetical protein FU13912 3.75
422219 AWg78073 Hs.1010 regulator of mitotic spindle assembly 1 3.75
418661 NM_001949 Hs.1189 E2F transcription fxtor 3 3.74
420726 K02402 Hs.1330 coagulation fxtor IX (plasma thrombopla 3.74
418413 R95735 Hs.117753 ESTs, Weakly similar to A48666 cell prol 3.73
443354 AW970672 Hs.9247 protein kinase, AMP-xtivated, alpha 1 c 3.73
406667 M12523 Hs.184411 albumin 3.72
436411 AW674352 gb:ba63c07.y1 NIH_MGC 12 Homo sapiens cD 3.72
417246 AI760098 Hs.21411 ESTs 3.72
410664 NM_006033 Hs.65370 lipase, endothelial 3.71
432686 BE223007 Hs.152460 Homo sapiens cDNA FU12900 fis, clone NT 3.70
442881 AI023175 Hs.167022 ESTs 3.70
432356 AA831032 Hs.111670 ESTs, Highly similarto JC2257 prolyl ol 3.70
450218 R02018 Hs.168640 aπkylosis, progressive (mouse) homolog 3.70
405460 NA NA 3.70
452824 W27643 Hε.73965 splicing fxtor, arginiπe/serine-rich 2 3.70 445873 AA250970 Hs.251946 poly(A)-binding protein, cytoplasmic 1-1 3.70
425282 AW163518 Hs.155485 huπtingtin interxting protein 2 3.60
439857 AA847194 Hε.232002 ESTs 3.69
430403 AF039390 Hs.241382 tumor nxrosis fxtor (ligand) superfami 3.69
444471 AB020684 Hs.11217 KIAA0877 protein 3.69
419559 Y07828 Hs.91096 ring finger protein 3.69
437641 AA811452 Hs.291911 ESTs 3.68
455364 H72176 Hε.4273 hypothetical protein FU13159 3.67
417791 AW965339 Hε.111471 ESTs 3.66
414271 AK000275 Hs.75871 protein kinase C binding protein 1 3.66
432023 AW273128 Hs.330144 EST 3.66
430294 AI538226 Hs.32976 guanine nucleotide binding protein 4 3.65
450600 BE079478 Hs.24880 ESTs 3.65
420505 AA278865 Hs.88523 ESTs 3.65
404477 NA NA 3.65
457003 S78234 Hs.172405 cell division cycle 27 3.65
443055 AV653742 Hs.15536 hypothetical protein DKFZp761J139 3.65
452220 BE158006 Hs.212296 ESTε 3.65
414463 T69078 Hs.76177 alpha-1-microglobuliπ/bikunin precursor 3.65
457465 AW301344 Hs.122908 DNA replication fxtor 3.64
436149 AI754308 Hs.159452 ESTs 3.63
433790 BE298215 Hs.288968 RAB22A, member RAS oncogene family 3.63
427920 Z11502 Hs.181107 annexinA13 3.63
424641 AB001106 Hs.151413 glia maturation fxtor, beta 3.63
426514 BE616633 Hs.170195 bone morphogenetic protein 7 (osteogenic 3.62
411975 AI916058 Hs.144583 ESTs 3.61
409239 AA740875 Hs.44307 ESTs, Moderately similarto I38022 hypot 3.61
429628 H09604 Hs.13268 ESTs 3.61
449722 BE280074 Hs.23960 cyclin B1 3.60
428389 AW135714 Hs.283127 ESTs, Weakly similar to T19201 hypotheti 3.60
419945 AW290975 Hs.118923 ESTs 3.60
410365 AI287518 Hs.62669 Homo sapiens mRNA; cDNA DKFZp586D0923 (f 3.60
420585 AW505139 Hs.9460 Homo sapiens mRNA; cDNA DKFZp547C244 (fr 3.60
407809 AW082279 Hs.244106 ESTs 3.60
457708 AA805443 Hs.179909 hypothetical protein FLJ22995 3.60
427943 AW05g075 Hs.238797 ESTs, Moderately similarto I38022 hypot 3.60
428771 AB028092 Hs.193143 KIAA1068 protein 3.60
446638 AL133063 Hs.15783 Homo sapienε mRNA; cDNA DKFZp434P1115 (f 3.59
418688 T85017 Hs.1192 KIAA0074 protein 3.59
436961 AW375974 Hs.156704 ESTε 3.58
430514 AA318501 Hs.241587 megakaryxyte-enhanced gene transcript 1 3.58
415245 N59650 Hs.27252 ESTs 3.57
452823 AB012124 Hs.30696 transcription fxtor-like 5 (basic helix 3.55
423508 AW604297 Hs.129711 hepatitis A virus cellular rxeptor 1 3.55
401165 NA NA 3.55
415382 AI743539 Hε.72465 ESTs, Weakly similar to non-lens beta ga 3.55
433968 AL157518 Hs.90421 PR02463 protein 3.55
421528 AB037837 Hs.105461 hypothetical protein FU20357 3.55
443325 BE398006 Hs.90462 Homo sapiens, clone IMAGE:4132043, mRNA, 3.55
444355 BE383686 Hs.191621 ESTs, Moderately similar to ALU6.HUMAN A 3.55
450715 AI266484 Hs.31570 ESTs, Weakly similarto KIAA1324 protein 3.55
427510 Z47542 Hs.179312 small nuclear RNA xtivating complex, po 3.55
455630 AV655701 Hs.75183 cytochrome P450, subfamily HE (ethanol- 3.55
441085 AW136551 Hs.181245 Homo sapiens cDNA FU 12532 fis, clone NT 3.54
434206 AW136973 Hs.288516 ESTs, Weakly similar to S69890 mitogeπ i 3.54
446619 AU076643 Hs.313 sxreted phosphoprotein 1 (osteopontin, 3.53
432542 AW083920 Hs.16098 claudin 2 3.53
433675 AW977653 Hs.75319 ribonucleotide reductase M2 polypeptide 3.52
423441 R68649 Hs.278358 absent in melanoma 1 like 3.51
452940 AA029722 Hε.2173 fucosyltraπsferase 4 (alpha (1 ,3) fucosy 3.51
440400 AA994364 Hs.125594 ESTε, Weakly similar to T25472 hypotheti 3.50
453439 AI572438 Hs.32976 guanine nucleotide binding protein 4 3.48
447247 AW369351 Hs.287955 Homo sapiens cDNA FU13090 fis, clone NT 3.48
449915 NM 004529 Hs.404 myeloid/lymphoid or mixed-lineage leukem 3.47
427975 AI536065 Hs.122460 ESTs 3.46
400297 AI127076 Hs.334473 hypothetical protein DKFZp56401278 3.45
404253 3.45
435567 AW504944 Hs.162090 Homo sapiens cDNA FU14193 fis, clone NT 3.45
432158 W33165 Hs.22983 UDP-glucose:glycoprotein glucosyltranεfe 3.45
417315 AI080042 Hs.336901 riboεomal protein S24 3.45
419140 AI982647 Hε.215725 ESTε 3.44
446901 AI347274 gb:tc05d02.x1 NCI_CGAP_Co16 Homo εapiens 3.43
451806 NM 003729 Hs.27076 RNA 3'-terminal phosphate cyclase 3.42
411571 AA122393 Hε.70811 hypothetical protein FU20516 3.42
442717 R88362 Hs.180591 ESTs, Weakly similar to T23976 hypotheti 3.41
443426 AF098158 Hs.9329 chromosome 20 open reading frame 1 3.41
419131 AA406293 Hs.41167 ESTs 3.41
430264 AA470519 gb:nc71f10.s1 NCI_CGAP_Pr1 Homo εapiens 3.40
450159 AI702416 Hs.200771 ESTs, Moderately similar to A Chain A, T 3.40
453531 AA417940 Hs.271400 ESTs, Weakly similar to JC5795 CDEP prot 3.40
444826 AI674482 Hs.148441 ESTs 3.40
445354 AV653485 Hs.6390 Homo sapiens clone FLB3344 PRO0845 mRNA, 3.40
444078 BE246919 Hs.10200 U5 snRNP-specific 40 kDa protein (hPrpβ- 3.40 418939 AW630803 Hε.894g7 lamin B1 3.40
418134 AA397769 Hs.86617 ESTs 3.40
430544 AA481066 Hs.105153 Homo sapiens, clone IMAGE:3461987, mRNA, 3.39
427927 AI879165 Hs.2227 CCAAT/enhancer binding protein (C/EBP), 3.39
410804 U64820 Hs.66521 Mxhado-Joseph disease (spin∞erebellar 3.39
410406 AI969703 Hε.1466 glycerol kinase 3.38
408494 AA554714 Hε.187578 Homo εapienε cDNA FU11639 fis, clone HE 3.38
452930 AW195285 Hε.194097 ESTs, Weakly similar to I38022 hypotheti 3.38
446432 AI377320 Hs.150058 ESTs 3.36
456653 AI807519 Hs.104520 Homo sapiens cDNA FU 13694 fis, clone PL 3.35
425322 U63630 Hs.155637 protein kinase, DNA-xtivated, catalytic 3.35
428261 AW006855 Hs.118392 ESTs, Weakly similar to LNHUER IgE Fc re 3.35
421039 NM 003478 Hs.101299 cullln 5 3.35
407819 R42185 Hs.274803 ESTs 3.35
424698 AA164366 Hs.151973 hypothetical protein FU23511 3.35
433361 AW469373 Hs.300141 ribosomal protein L39 3.35
435022 AW183385 Hs.54627 ESTs, Weakly similar to FTDH_HUMAN 10-FO 3.35
447164 AF026941 Hs.17518 Homo sapienε cig5 mRNA, partial sequence 3.35
454018 AW016892 Hs.100855 ESTs 3.35
430871 R88518 Hs.46736 hypothetical protein FLJ23476 3.35
453941 U39817 Hs.36820 Bloom syndrome 3.34
411560 AW851186 Hs.179909 hypothetical protein FU22995 3.33
435532 AW2gi488 Hs.117305 Homo sapienε, done IMAGE:3682908, mRNA 3.33
438008 AA775026 Hs.203802 ESTε 3.33
421246 AW582862 Hε.102897 CGI-47 protein 3.33
451707 AW051061 Hs.60973 ESTs 3.33
457574 H88717 Hs.27774 ESTs, Highly similar to AF161349 1 HSPC0 3.31
443613 AI079356 gb;oz39b09.s1 Soares_NhHMPu_S1 Homo εapi 3.31
415857 AA866115 Hs.127797 Homo εapiens cDNA FU11381 fis, clone HE 3.31
438746 AI885815 Hs.184727 ESTs 3.30
408660 AA525775 Hs.292523 ESTs, Moderately similarto PC4259 feπi 3.30
427738 NM 000318 Hs.180612 peroxisomal membrane protein 3 (35kD, Ze 3.30
458855 AW361289 Hs.107000 hypothetical protein FU11294 3.30
417221 AW379029 Hs.118338 ESTs, Weakly similar to unnamed protein 3.30
424770 AA425562 Hs.11065 Homo sapienε HDCME13P mRNA, partial cdε 3.30
417720 AA205625 Hs.208067 ESTs 3.29
428571 NM 006531 Hs.2291 Probe hTg737 (polycystic kidney disease, 3.29
452862 AW378065 Hs.8687 ESTs 3.28
414343 AL036166 Hs.323378 coated vesicle membrane protein 3.28
437222 AL117588 Hs.12778 ESTs 3.28
422665 AJ011812 Hs.119018 transcription fxtor NRF 3.28
414706 AW340125 Hs.76989 KIAA0007 gene product 3.28
446565 D13757 Hs.311 phoεphoribosyl pyrophosphate amidotransf 3.27
447820 AI433029 Hs.164104 ESTs 3.27
427576 BE242611 Hs.2173 fucosyltransferase 4 (alpha (1 ,3) fucosy 3.27
456132 BE219771 Hs.237146 hypothetical protein FU 12752 3.26
407305 AA715284 gb:nv35f03.r1 NCI_CGAP_Br5 Homo sapienε 3.26
419741 NM_007019 Hs.93002 ubiquitin carrier protein E2-C 3.26
424581 M62062 Hs.150917 catenin (cadherin-aεε∞iated protein), a 3.25
445592 AV654382 Hs.17947 ESTε, Weakly similar to T16534 hypotheti 3.25
453320 AW450240 Hε.257274 ESTs 3.25
451797 AW663858 Hs.333513 small inducible cytokine subfamily E, me 3.25
413930 M86153 Hs.75618 RAB11A, member RAS oncogene family 3.25
410659 A1080175 Hs.68826 ESTs 3.25
446202 AI279706 Hs.149474 ESTs 3.25
432193 AA372264 Hs.273193 hypothetical protein FU10706 3.25
439262 AA832333 Hε.333045 ESTs 3.25
401823 NA NA 3.25
441264 AA927170 Hs.23290 ESTs 3.25
424081 NM 00641c 1 Hs.139120 ribonuclease P (30kD) 3.24
408321 AW405882 Hε.44205 cortistatin 3.24
447432 AW958473 Hs.301957 nudix (nucleoside diphosphate linked moi 3.24
404519 3.24
443268 AI800271 Hs.129445 hypothetical protein FU12496 3.23
422660 AW297582 Hs.103267 hypothetical protein FU22548 similar to 3.23
427961 AW293165 Hs.143134 ESTs 3.22
427660 AI741320 Hs.114121 Homo sapienε cDNA: FU23228 fis, clone C 3.22
411643 AI924519 Hs.192570 hypothetical protein FU22028 3.21
458652 AW375610 Hs.117102 hypothetical protein FU13046 similar to 3.21
426472 BE246138 Hs.30853 ESTs 3.21
410389 AW954049 Hε.8177 ESTs, Weakly similar to PIHUB6 salivary 3.21
439979 AW600291 Hs.6823 hypothetical protein FU 10430 3.21
422363 T55979 Hs.115474 replication factor C (xtivator 1) 3 (38 3.20
443162 T49951 Hs.9029 DKFZP434G032 protein 3.20
431678 AW072372 Hs.267446 hypothetical protein FU11184 3.20
430439 AL133561 Hs.241426 DKFZP434B061 protein 3.20
407201 N31998 Hs.164256 hypothetical protein FU20657 3.20
437905 AW363121 Hs.175596 ESTs, Weakly similar to T26935 hypotheti 3.20
434160 BE551196 Hs.114275 ESTs 3.20
407995 AI094748 Hs.100134 hypothetical protein FU12787 3.20
412966 BE243311 Hs.8024 IK cytokine, down-regulator of HLA II 3.19
414386 X00442 Hs.75990 haptoglobiπ 3.19
444381 BE387335 Hε.283713 ESTs, Weakly similar to S64054 hypotheti 3.18 429597 NM_003816 Hs 2442 a disintegnn and metaltoproteinase doma 318
433764 AW753676 Hs 39982 ESTs 317
459370 AA889982 Hs 271826 ESTs, Weakly similar to I38022 hypotheti 3 17
429616 AI982722 Hs 120845 ESTs 317
415083 AI632683 Hs 27179 Homo sapiens cDNA FU 12933 fis, clone NT 316
424687 J05070 Hs 151738 matnx metalloprotemase 9 (gelatinase B 3 16
428839 AI767756 Hs 82302 Homo sapiens cDNA FU14814 fis, clone NT 316
423629 AW021173 Hs 18612 Homo sapiens cDNA FLJ21909 fis, clone H 315
443830 AI142095 Hs 143273 ESTs 3 15
413516 BE145907 gb MR0-HT0208 221299-204^12 HT0208 Homo 315
433527 AW235613 Hs 133020 ESTs 3 15
427986 N45214 Hs 282387 Homo sapienε cDNA FU21837 fis, clone H 315
457453 Z70695 Hs 272240 Homo sapiens cDNA FU11086 fis, clone PL 315
427687 AW003867 Hs 1570 histamine rxeptor H1 315
455068 AI807894 Hs 47274 Homo εapiens mRNA, cDNA DKFZp564B176 (fr 3 15
441720 AI346487 Hs 28739 ESTs 315
419569 AI971651 Hs 91143 jagged 1 (Alagille syndrome) 315
445921 AW015211 Hs 146181 ESTs 315
429957 AW204530 Hs 99500 ESTs 315
403137 314
425268 AI807883 Hε 180059 Homo sapiens cDNA FU20653 fis, clone KA 314
428645 AA431400 Hε 98729 ESTs, Weakly similar to 2017205A dihydro 314
439635 AA477288 Hs 94891 hypothetical protein FU22729 314
408806 AW847814 Hs 289005 Homo sapiens cDNA. FU21532 fis clone C 314
439277 R80061 Hs 164478 hypothetical protein FU21939 similar to 313
443584 AI807036 Hs 267245 hypothetical protein FU14803 313
406668 T62745 Hs 184411 albumin 3 13
452194 AI694413 Hs 332649 olfxtory rxeptor, family 2, subfamily 313
4375g4 AA761431 Hs 74335 heatsh∞k90kD protein 1, beta 313
433759 AA680003 Hs 109363 Homo εapienε cDNA FU23603 fis, clone L 3 13
420911 U77413 Hs 100293 0 linked N-xetylglucosamine (GlcNAc) tr 313
414080 AA135257 Hs 47783 B aggressive lymphoma gene 3 11
450209 AW008921 Hs 13138 Homo sapiens, clone IMAGE 3448343, mRNA 311
441790 AW294909 Hs 132208 ESTs 311
439352 BE614347 Hs 169615 hypothetical protein FU20889 3 10
449664 R06212 Hs 127733 ESTs 310
435979 W03698 Hs 83513 ESTs, Weakly similarto ALU1_HUMAN ALU S 310
424602 AK002055 Hs 151046 hypothetical protein FU11193 310
402063 310
428967 AW978441 Hs 296100 ESTs 310
455838 BE145808 gb MR0-HT0208-101299-103-f 11 HT0208 Homo 310
407502 U52096 gb Human zinc finger protein (kr-znfl) m 310
426853 U32974 Hs 172777 bxuloviral IAP repeat-containing 4 310
417845 AL117461 Hs 82719 Homo sapiens mRNA, cDNA DKFZp586F1822 (f 310
421056 AI076890 Hs 146847 TRAF family member-asε∞iated NFKB xtiv 310
420617 AK001652 Hs 99423 ATP-dependent RNA helicase 310
421841 AAg08197 Hs 108850 MAK-reiated kinase 310
429534 AW976987 Hs 163327 ESTs, Weakly similarto 2109260A B cell 310
408353 BE439838 Hs 44298 mit∞hondnal πbosomal protein S17 310
433037 NM 01415E I Hs 279938 HSPC067 protein 309
443183 R16258 Hε 6217 Homo sapiens cDNA FU 12521 fis, clone NT 309
457726 AI217477 Hε 194591 ESTs 309
415786 AW419196 Hs 257924 hypothetical protein FU 13782 308
433013 AI697890 Hε 127337 axin 2 (conductin, axil) 308
417601 NMJ1473Ϊ i Hs 82292 KIAA0215 gene product 308
420276 AA290938 Hε 190561 ESTs, Highly similar to SORL_HUMAN SORTI 307
443323 BE560621 Hs 9222 estrogen receptor binding site ass∞iate 307
446223 BE300091 Hs 119699 hypothetical protein FU 12969 307
425851 NM 001490 Hs 159642 glucosammyl (N-acetyl) transferase 1, c 307
436203 BE384982 Hs 5076 Homo εapienε cDNA FU22128 fis, clone H 307
416402 NM_000715 Hs 1012 complement component 4-bιndιng protein, 306
436554 AI985810 Hε 301173 ESTs 306
413801 M62246 Hs 35406 ESTs, Highly similarto unnamed protein 306
416248 H99169 Hs 23450 mitochondπal πbosomal protein S25 306
445413 AA151342 Hs 12677 CGI-147 protein 306
452909 NM 015368 Hs 30985 pannexin 1 306
447048 AW393080 Hε 228320 hypothetical protein FU23537 305
425942 AU077195 Hs 164036 glucosamine (N-xetyl)-δ-sulfatase (Sanf 305
406333 305
428454 U55936 Hs 184376 synaptosomal assxiated protein, 23kD 305
411864 AW948147 gb RC0-MT0013-280300-031-e03 MT0013 Homo 305
458632 AI744445 Hs 167073 Homo sapiens cDNA FU13047 fis, clone NT 305
448292 BE281316 Hs 47334 hypothetical protein FU14495 305
450055 N23235 Hs 30567 ESTs, Weakly similar to B34087 hypotheti 305
402167 305
433133 AB027249 Hs 104741 PDZ-bmding kinase, T-cell oπginated pr 305
437828 AW976806 i Hs 73149 paired box gene 8 305
404232 305
418164 AI761820 Hs 41074 ESTs, Weakly similarto 139294 McLeod sy 305
412610 X80908 Hs 74126 fatty xid binding protein 6, ileal (gas 305
452787 AW294023 I Hs 222707 KIAA1718 protein 305
425782 U66468 Hs 159525 i cell growth regulatory with EF-hand doma 305
410718 AI920783 Hs 191435 i ESTs 304 419196 AF110908 Hs 297660 TNF r eptor-aεsociated fxtor 3 304
446861 AI696519 Hs 14427 Homo sapiens cDNA FU21800 fis, clone H 303
425492 AL021918 Hs 158174 zinc finger protein 184 (Kruppel like) 302
452834 AI638627 Hs 105685 KIAA1688 protein 302
410102 AW248508 Hs 279727 Homo sapiens cDNA FLJ14035 fis, clone HE 302
416568 H64844 Hs 138558 ESTs 302
425834 NM 001630 Hs 1957 amyloid P component, serum 302
426711 AA383471 Hs 180669 conserved gene amplified in osteosarcoma 301
412719 AW016610 Hs 129911 ESTs 301
439586 AA922936 Hs 110039 ESTs 301
422867 L32137 Hs 1584 cartilage oligomeπc matnx protein (pse 301
429703 T93154 Hs 28705 ESTs 300
400296 AA305627 Hs 139336 ATP-binding cassette, sub-family C (CFTR 300
415261 T40028 Hs 8346 ESTs 300
419435 AI200540 Hs 14877 ESTs, Weakly similar to (defliπe not ava 300
429985 NM 015836 Hs 227274 tryptophanyl tRNA synthetase 2 (mitxhon 300
423038 D26528 Hs 123058 DEAD/H (Asp-Glu Ala-Asp/His) box polypep 300
407182 AA312551 Hs 230157 ESTε 300
424202 BE350295 Hε 15032 RAN binding protein 17 300
444585 AW170015 Hs 6594 ESTs 300
420552 AK000492 Hs 98806 hypothetical protein - 300
451939 U80456 Hs 27311 single minded (Drasophila) homolog 2 300
441928 AI370188 Hs 211454 ESTs 300
430888 BE155293 Hs 76064 πbosomal protein L27a 300
417806 AI867277 Hs 183733 ESTs 300
447175 AI365208 Hs 203606 ESTs 300
417177 NM 004458 Hε 81452 fatty-xid Coenzyme A ligase, long-chain 300
435447 AI872932 gb wm72e03 x1 NCI_CGAP_Ut2 Homo sapiens 300
405394 300
454975 AW848047 gb IL3-CT0214-291299 052 A12 CT0214 Homo 300
441535 AL135735 Hs 7885 phosphatidylmositol binding clathnn as 300
428361 NM 015905 i Hs 183858 transcπptional Intermediary fxtor 1 300
TABLE 6B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accesεion Genbank acceεεion numbers
Pkey CAT number Accession
411765 125700J H43346 AA248302 AA095182
411864 1262055J AW948147 BE092318 AW948138 AW948130 AW948148 AW948129 AW948136 AW948152 AW948144 AW948137 AW948160
412359 129085.1 AW837985 AW837938 AA101955 AW837913 AW837935
413516 1374595 1 BE145907 BE145796 BE145803 BE145851 BE145923 BE145812 BE145809 BE145852 BE145856
414148 142133 1 BE084049AW292907AA135984
424492 240008 AI133482 AI207619AA341626
430264 315008J AA470519 BE303010 BE302954 BE384120
431064 327472J AI903735AA491283AI694953AW976903AA761362
433687 373061 AA743991 AA604852 AW272737
434414 38585J AI798376 S46400 AW811617 AW811616 W00557 BE142245 AW858232 AW861851 AW858362 AA232351 AA218567 AA055556 AW858231
AW857541 AW814172 H66214 AW814398 AF134164 AA243083 AA173345 AA199942 AA223384 AA227092 AA227080 T12379 AA092174 T61139
AA149776 AA699829AW879188 AW813567 AW813538AI267168 AA157718 AA1577ig AA100472AA100774AA130756AA157705 AA157730
AA157715 AA053524 AW849581 AW854566 C05254 AW882836 T92637 AW812621 AA206583 AA209204 BE156900 AA226824 AI828309 AWggi957
N66951 AA527374 H66215 AA045564 AI694265 H60808 AA149726 AW195620 BE081333 BE073424 AW817662 AW817705 AW817703 AW817659
BE081531 H59570
435447 406400 1 AI872932 AA682306 BE220163 W88605 T81307 H91447
436411 419334 1 AW674352AA715374Z25205
443613 575391 1 A1079356W23287
446901 697809 1 AI347274AW844024
448310 757918 1 AI480316 AW847535
451401 868474 1 AI793163 AW875182 AW875178 AW875176
454403 1170435 1 BE065985 BE065944 BE066008 BE066083 BE066093
454975 1247077J AW848047 AW848202 AW848631 AW848142 AW848702 AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069 AW848905
AW848214
455838 1374605 BE145808 BE145807 BE181883
TABLE 6C
Pkey U I nique number corresponding to an Eos probeset
Ref S ( equence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1899) 402489495
Strand I Indicates DNA strand from which exons were predicted
N position I1ndicates nucleotide positions of predicted exons Pkey Ref Strand N position
400534 6981826 Minus 278637-279292
401165 9438376 Minus 168244-168423
401480 7321503 Plus 166120-166347,166451-166557,169651-169832
401644 8576138 Pluε 82655-83959
401823 2262095 Minus 42575-42697,43189 43287,4583045974
402167 8571795 Plus 109122-110357
402963 5419653 Minus 12950-15959
403137 9211494 Minus 92349-92572,92958 93084,93579937129394994072,94591-94748,95214-95337
403776 7770611 Minus 1414-1513,1624-1756
404025 7341444 Plus 131740-131905
404232 8218045 Minus 71800-71956
404253 9367202 Minus 55675-56055
404477 8080699 Plus 113390-113577
404516 8151967 Plus 114153-114322
404519 8152000 Plus 12817-13000
404567 7249169 Minus 101320-101501
404996 6007890 Plus 3799938145,38652-38998,39727-39872,40557-40674,42351-42450
405394 6624123 Minus 31900-32373
405460 7684569 Minus 52223-52389
405769 3046270 Minus 76844-77193
406117 9142932 Plus 54304-54584
406333 9213235 Plus 64689-64798
406360 9256107 Minus 7513-7673
406414 9256407 Plus 49593-49850
TABLE 7A 516 GENES UP-REGULATED IN COLON CANCER COMPARED TO NORMAL COLON
Table 7A lists 516 genes up-regulated in coton cancer compared to normal colon These were selxted as for Table 6A except for using all CEP and colon sample in the normal body tissue list as the normal samples in determining the denominator value and the ratio was equal to or greater than 50
Pkey Unique Eos probeset identifier number
ExA∞n Exemplar Acceεεion number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of tumor to normal colon
Pkey ExAccn UnigenelD Unigene Title R1
441031 AI110684 Hs 7645 fibπnogen, B beta polypeptide 5752
406667 M12523 Hs 184411 albumin 4 4
409041 AB033025 Hs 50081 KIAA1199 protein 4918
428330 L22524 Hs 2256 matnx metalloprotemase 7 (matπlysin, 4222
421552 AF026692 Hε 105700 sxreted fπzzled related protein 4 3464
429201 X03178 Hs 198246 graup-spxific component (vitamin D bind 3338
452281 T93500 Hs 28792 Homo sapiens cDNA FU 11041 fis, clone PL 33 10
447033 AI357412 Hs 157601 ESTs 31 24
428839 AI767756 Hs 82302 Homo sapiens cDNA FU14814 fis, clone NT 2684
438461 AW075485 Hs 286049 phosphoseπne amiπotransferase 2540
413841 M34276 Hs 75576 plasmmogeπ 2468
428187 AI687303 Hs 285529 G protein-coupled rxeptor 49 2400
408806 AW847814 Hs 288005 Homo sapiens cDNA FU21532 fis, clone C 2318
452862 AW378065 Hs 8687 ESTs 21 34
415989 AI267700 Hs 317584 ESTs 2092
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid etaph 1922
421470 R27496 Hs 1378 annexιnA3 1792
424051 AL110203 Hs 138411 Homo sapiens mRNA, cDNA DKFZp586J1822 (f 1736
439759 AL359055 Hs 67709 Homo sapiens mRNA full length insert cDN 1728
449032 AA045573 Hs 22900 nuclear fxtor (erythroid-denved 2)-lιk 1708
421462 AF016495 Hs 104624 aquapoπn 9 1702
424252 AK000520 Hs 143811 hypothetical protein FU20513 1698
452823 AB012124 Hs 30696 transcnption fxtor like 5 (basic helix 1670
432340 AA534222 gb nj21d02 s1 NCI_CGAP_AA1 Homo sapiens 1664
433447 U29195 Hs 3281 neuranal pentraxm II 1659
414386 X00442 Hs 75990 haptoglobm 16 19
425260 L47726 Hs 1870 phenylalanine hydroxylase 1608
444754 T83911 Hs 11881 transmembrane 4 superfamily member 4 1582
439518 W76326 gb zd60d04 r1 Soares_fetal_heart_NbHH19W 1580
443211 AI128388 Hs 143655 ESTs 1578
439608 AW864696 Hs 301732 hypothetical protein MGC5306 1552
414559 AV656184 Hs 76452 C-rextive protein, pentraxm related 1542
412719 AW016610 Hs 129911 ESTs 1524
439451 AF086270 Hs 278554 heterochromatin like protein 1 15 18
448974 AL049390 Hs 22689 Homo sapiens mRNA cDNA DKFZp58601318 (f 1503 416402 NM 000715 Hs 1012 complement component 4-bmdιng protein, 1460
453863 X02544 Hs 572 orosomucoid 1 1435
441243 AI767056 Hs 193002 ESTs 1430
413318 AU076607 Hs 75285 inter-alpha (globulin) inhibitor, H2 pol 1430
451817 AW391351 Hs 50820 Homo sapiens unknown mRNA 1391
433213 AW665130 Hs 137190 ESTs 1380
428261 AW006855 Hs 118392 ESTs, Weakly similar to LNHUER IgE Fc re 1352
438578 AA811244 Hs 164168 ESTs 1340
429170 NM 001394 Hs 2359 dual spxificity phosphatase 4 1336
417006 AW673606 Hs 80758 aspartyl tRNAεynthetase 1300
449199 AI990122 Hs 196988 ESTs 1298
436393 AW022213 Hs 143617 ESTs 1290
413585 AI133452 Hs 75431 fibπnogeπ, gamma polypeptide 1283
451561 N52812 Hs 177403 ESTs 1272
420734 AW972872 Hs 293736 ESTs 1270
422420 U03398 Hs 1524 tumor nxrosis factor (ligand) superfami 1250
441377 BE218239 Hs 202656 ESTs 1245
435981 H74319 Hs 188620 ESTs 1238
417296 L36196 Hs 81884 sulfotraπsferase family, cytosolic, 2A, 1238
428664 AK001666 Hs 189095 similarto SALL1 (sal (Drasophila) like 1238
459370 AA889982 Hs 271826 ESTs, Weakly similar to I38022 hypotheti 1234
430290 AI734110 Hs 136355 ESTs 1230
450221 AA328102 Hs 24641 cytoskeleton associated protein 2 1226
450628 AW382884 Hs 204715 ESTs 1224
446232 AI281848 Hs 194691 retinoic xid induced 3 12 16
428223 AA424313 Hs 98402 ESTs 1208
432582 AI623817 Hs 168457 ESTs 1208
407884 BE075316 Hs 95011 syntrophm, beta 1 (dystrophin associate 1202
428493 AK001745 Hs 184628 hypothetical protein FU 10883 1201
407202 N58172 Hs 109370 ESTs 11 84
422109 S73265 Hs 1473 gastπn-releasing peptide 11 68
434699 AA643687 Hs 149425 Homo sapiens cDNA FU 11980 fis, clone HE 11 68
447532 AK000614 Hs 18791 hypothetical protein FLJ20607 11 67
443162 T49951 Hs 9029 DKFZP434G032 protein 11 67
450149 AW06g781 Hs 132863 Zic family member 2 (odd paired Drosophi 11 62
446372 AB020644 Hs 14945 long fatty xyl-CoA synthetase 2 gene 11 46
453800 AW004045 Hs 203365 ESTs 11 42
416655 AW968613 Hs 79428 BCL2 adenovιrus E1B 19kD interacting pro 11 34
452903 AI953425 Hs 246911 ESTs, Weakly similarto 138022 hypotheti 11 32
433011 H07960 Hs 306044 CGI 05 protein 11 30
423575 C18863 Hs 163443 Homo sapienε cDNA FLJ11576 fis, clone HE 11 22
455777 AA524285 Hs 154172 ESTs, Moderately similar to BCGF_HUMAN B 11 20
425745 U44060 Hs 14427 Homo sapiens cDNA FU21800 fis, clone H 11 08
407168 R45175 Hs 117183 ESTs 1091
407633 NM 00706S l Hs 37189 similar to rat HREV107 1090
400534 1088
450434 AA166950 Hs 195870 hypothetical protein FU140gi 1076
445873 AA250970 Hs 251946 poly(A)-bιndιng protein, cytoplasmic 1-1 1068
440526 AI832243 Hs 211471 ESTs 1063
427544 AI767152 Hs 181400 ESTs, Weakly similarto 178885 seπne/th 1062
447974 R76886 gb yι64b03 s1 Soareε placenta Nb2HP Homo 1052
431958 X63629 Hε 2877 cadhenn 3, type 1, P-cadheπn (plxenta 1052
453922 AF053306 Hs 36708 budding uninhibited by benzimidazoleε 1 1050
457065 AI476318 Hs 192480 ESTs 1040
408950 AA707814 Hs 14945 long fatty xyl-CoA synthetase 2 gene 1038
419852 AW503756 Hs 286184 hypothetical protein dJ551D25 1034
414718 H95348 Hs 107987 ESTs 1029
447505 AL049266 Hs 18724 Homo sapiens mRNA, cDNA DKFZp564F093 (fr 1028
404567 1014
428536 AI143139 Hs 2288 visinin like 1 1006
444381 BE387335 Hs 283713 ESTs, Weakly similarto S64054 hypotheti 1005
437267 AW511443 Hs 258110 ESTs 1000
420583 H77859 Hs 65450 retieulon 4 1000
407244 M10014 Hs 75431 fibπnogen, gamma polypeptide 999
425071 NM 013989 Hs 154424 deiodmase, lodothyronme, type II 997
449655 AI021987 Hs 59970 ESTs 991
459504 BE514127 gb 601315974F1 NIH_MGC_8 Homo sapiens cD 990
434609 R76593 gb yι60o11 Soares plxenta Nb2HP Homo 990
412104 AW205197 Hs 240951 Homo sapiens, Similarto RIKEN cDNA 2210 988
447863 AL047611 Hs 288885 Homo sapiens cDNA FU14246 fis, clone OV 984
448106 AI800470 Hs 171941 ESTs 964
439192 AW970536 i Hs 105413 ESTs 964
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontin, 961
427535 R20543 Hs 2164 pro-platelet basic protein (includes pla 950
440591 AA43159g Hs 132799 hypothetical protein FLJ23451 944
440404 AI015881 Hs 324527 mitochondπal nbosomal protein S5 940
426283 NM_003037 Hs 169139 kynurenmase (L-kynureniπe hydrolase) 936
401742 NA NA 930
416393 N54037 Hs 262869 plasminogen like 928
413339 AI818080 Hs 194290 ESTs 928
437641 AA811452 Hs 291911 ESTs 928
428743 AL080060 Hs 301549 Homo sapiens mRNA, cDNA DKFZp564H172 (fr 922
431319 AA873350 Hs 302232 ! ESTs 921 434008 AA740878 Hs 112982 ESTs 920
446311 AW007294 Hs 149795 ESTs, Moderately similar to ALULHUMAN A 916
419968 X04430 Hs 93913 interleukin 6 (interferon, beta 2) 916
413597 AW302885 Hs 117183 ESTs 915
440527 AV657117 Hs 184164 ESTs, Moderately similar to S65657 alpha 914
409327 L41162 Hs 53563 collagen, type IX, alpha 3 914
444107 T46830 Hs 10319 UDP glycosyltransferase 2 family, polype o5
456653 AI807519 Hs 104520 Homo sapiens cDNA FLJ13694 fis, clone PL 808
450164 AI239923 Hs 30098 ESTs 895
432867 AW016036 Hs 233364 ESTs 893
437396 BE140396 Hs 21621 hypothetical protein DKFZp762O076 892
421126 M74587 Hs 102122 insulin like growth fxtor binding prate 892
452712 AW838616 gb RC5-LT0054-140200-013-D01 LT0054 Homo 890
419131 AA406293 Hs 41167 ESTs 886
444783 AK001468 Hs 62180 anillin (Drasophila Scraps homolog), xt 882
418895 AA894638 Hs 14600 ESTs 882
422665 AJ011812 Hs 119018 transcnption fxtor NRF 882
400757 NM 001898 Hs 123114 cystatin SN 878
419752 AA249573 Hs 152618 ESTs, Moderately similar to ZN91_HUMAN Z 874
412446 AI768015 Hs 92127 ESTs 871
433285 AW975944 Hs 237396 ESTs 868
414538 AW612228 Hs 107987 ESTs 864
449318 AW236021 Hs 78531 Homo sapiens, Similar to RIKEN cDNA 5730 862
430835 AI240006 Hs 192326 ESTs 860
445467 AI239832 Hs 15617 ESTs, Weakly similar to ALU4_HUMAN ALU S 858
445537 AJ245671 Hs 12844 EGF-like-domam, multiple 6 852
450375 AA00g647 Hs 8850 a disintegnn and metalloprotemase doma 852
428355 BE256452 Hs 2257 vitronectin (serum spreading fxtor, som 850
444478 W07318 Hs 240 M phaεe phosphoprotem 1 847
439398 AA284267 Hs 221504 ESTs 844
428368 BE440042 Hs 83326 matnx metalloprotemase 3 (stromelysin 843
403776 842
418973 AA233056 Hs 191518 ESTs 842
445436 AI224105 Hs 151408 ESTs 838
417958 AA767382 Hs 193417 ESTs 834
452838 U65011 Hs 30743 preferentially expressed antigen in mela 834
425761 AW664214 Hs 196729 ESTs 833
449419 R34910 Hs 119172 ESTs 820
407007 U22961 gb Human mRNA clone with similanty to L 828
420900 AL045633 Hs 44269 ESTs 825
452503 AB000509 Hs 29736 TNF receptor-ass∞iated fxtor 5 823
458242 BE299588 Hs 28465 Homo sapiens cDNA FU21868 fis, clone H 818
420120 AL049610 Hs g5243 transcnption elongation fxtor A (Sll)- 816
432363 AA534489 gb nf76g11 s1 NCI_CGAP_Co3 Homo sapiens 816
418738 AW388633 Hs 6682 solute earner family 7, (cationic ammo 812
446155 AI553695 Hs 159422 Homo sapiens cDNA FU13997 fis, clone Y7 810
418379 AA218940 Hs 137516 fϊdgetin-like 1 807
424560 AA158727 Hs 150555 protein predicted by clone 23733 806
453116 AI276680 Hs 146086 ESTs 804
419929 U90268 Hs 93810 cerebral cavernous malformationε 1 804
409687 T51125 Hs 8493 ESTs 800
407790 AI027274 Hs 288941 Homo sapiens cDNA FU14866 fis, clone PL 800
416661 AA634543 Hs 79440 IGF-II mRNA-bmding pratem 3 800
418036 Z37976 Hs 83337 latent tranεforming growth fxtor beta b 799
422762 AL031320 Hs 119976 Human DNA sequence from clone RP1-20N2 o 796
421633 AF121860 Hs 106260 sorting nexin 10 792
432542 AW083920 Hs 16098 claudin 2 786
414869 AA157291 Hs 21479 ubinuclein 1 784
419502 AU076704 Hs 90765 fibπnogen, A alpha polypeptide 780
406666 V00495 Hs 184411 albumin 778
418007 M13509 Hs 83169 matnx metaltoproteinase 1 (interstitial 778
439616 BE018635 Hs 58582 Homo sapiens cDNA FU 12789 fis, clone NT 777
406360 NA NA 776
406687 M31126 Hs 272620 pregnancy spxific beta-1-glycoprotein 9 776
431510 AA58O082 Hs 112264 ESTε 776
414312 AA155694 Hs 191060 ESTs 771
443450 N66045 Hs 133529 ESTs 770
449870 AI672487 Hs 15423 hypothetical protein HDCMC04P 764
425681 AB018297 Hs 159183 KIAA0754 protein 763
408897 N50204 Hs 283709 Iipopolysacchaπde spxific reεponse-7 p 62
443285 AI301918 Hs 334264 ESTs 760
420807 AA280627 Hs 57846 ESTs 760
424650 AW576156 Hs 250824 Homo sapiens cDNA FU23435 fis, clone H 760
410718 AI920783 Hs 191435 ESTs 760
430848 AW021726 gb df27e02 y1 Morton Fetal C∞hlea Homo 760
434294 AJ271379 Hs 76194 πbosomal protein S5 760
445808 AV655234 Hs 298083 ESTs, Moderately similar to PC4259 fern 756
438604 AA811896 Hs 44604 ESTs 754
458997 AW937420 Hs 69662 ESTs 754
400289 X07820 Hs 2258 matnx metaltoproteinase 10 (stromelyεin 754
409187 AF154830 Hs 50966 carbamoyl phosphate synthetase 1, mit∞h 752
445640 AW969626 Hs 31704 ESTs, Weakly similarto KIAA0227 [H sapi 749
404996 748 420759 T11832 Hε 127797 Homo sapiens cDNA FU11381 fis, clone HE 748
433859 AW896758 Hs 273789 ESTs 744
423952 AW877787 Hs 136102 KIAA0853 protein 744
431193 AW749505 Hs 296770 KIAA1719 protein 743
413530 AA130158 Hε 19977 ESTs, Moderately similar to ALU8_HUMAN A 740
417479 AI057052 Hs 133554 ESTs Weakly similarto Z195_HUMAN ZINC 740
424613 AL079850 Hs 151236 highly charged protein 7 37
417720 AA205625 Hs 208067 ESTs 735
440347 AV649748 Hs 295901 KIAA0493 protein 734
449444 AW818436 Hs 23590 solute earner family 16 (mon∞arboxylic 7 34
447499 AW262580 Hs 147674 protocadhenn beta 16 732
426890 AA383167 Hs 41294 ESTs 731
450568 AL050078 Hs 25159 Homo sapienε cDNA FLJ10784 fis, clone NT 728
445019 AI205540 Hs 281295 ESTs 7 28
419474 AW968619 Hs 155849 ESTs 724
417015 M83772 Hs 80876 flavin containing moπooxygenase 3 724
411765 H43346 gb yp09a04 r1 Soares breast 3NbHBst Homo 724
448816 AB033052 Hε 22151 KIAA1226 protein 718
416143 AI955650 Hs 79033 glutammyl peptide cyclotransferase (glu 718
451815 AW974911 Hs 184793 Homo sapiens cDNA FU21880 fis, clone H 718
420777 AA280223 Hs 130865 ESTs 7 16
414463 T69078 Hs 76177 alpha-1-mιcroglobulιn/bιkunιn precursor 714
409269 AA576953 Hs 22972 hypothetical protein FU 13352 714
443614 AV655386 Hs 7645 fibπnogen, B beta polypeptide 714
448706 AW291095 Hs 21814 interleukin 20 rxeptor, alpha 7 13
441124 T97717 Hs 119563 ESTs 712
414680 AA743331 Hs 272572 hemoglobin, alpha 2 710
446432 AI377320 Hs 150058 ESTs 710
439295 AW206001 Hs 253536 ESTs 708
436902 AW247145 Hs 192729 ESTε 708
428679 AA431765 gb zw80c03 s1 Soares_testis_NHT Homo sap 708
414865 AA157155 Hs 274414 hypothetical protein FLJ14457 708
421373 AA808229 Hs 167771 ESTs 706
432435 BE218886 Hs 282070 ESTs 705
427933 AW974643 Hs 190571 ESTs 704
436330 NM 004413 Hs 109 dipeptidase 1 (renal) 704
433800 AI034361 Hs 135150 lung type-l cell membrane-ass∞iated gly 701
418763 AK000219 Hε 88367 hypothetical protein FU20212 698
446322 N23033 Hε 155814 ESTs 698
442577 AA202g98 Hε 163900 ESTs 696
429486 AF155827 Hε 203963 hypothetical protein FU 10338 694
412280 AW205116 Hε 272814 hypothetical protein DKFZp434E1723 692
436679 AI127483 Hε 120451 ESTs, Weakly similar to unnamed protein 690
429125 AA446854 Hs 271004 ESTs, Weakly similar to 138022 hypotheti 690
453204 R10799 Hs 191990 ESTs 690
431576 M76665 Hs 275215 hydroxysteroid (11-beta) dehydrogenase 1 688
427878 C05766 Hs 181022 CGI 07 protein 688
454438 AA224053 Hs 172405 cell division cycle 27 686
424402 M63108 Hs 1769 luteinizing hormone/chonogonadotropm r 686
438394 BE379623 Hs 27693 peptidylprolyl isomerase (cyclophilin) I 684
414271 AK000275 Hs 75871 protein kinase C binding protein 1 680
417168 AL133117 Hs 81376 Homo sapienε mRNA, cDNA DKFZp586L1121 (f 680
419629 AB020605 Hs 91662 KIAA0888 protein 680
451686 AA059246 Hs 110293 ESTs 680
430829 AW451999 Hs 194024 ESTs 678
446501 AI302616 Hs 150819 ESTs 678
442973 BE567665 Hs 288550 Homo sapiens cDNA FU23156 fis, clone L 678
457030 AI301740 Hs 173381 dihydropyπmidinase-like 2 676
437773 U24186 Hs 283018 replication protein A complex 34 kd subu 673
416018 AW138239 Hs 78977 proprotem convertase εubtiliεin/kexm t 672
425478 AB007953 Hs 268840 ESTs 670
411643 AI924519 Hs 192570 hypothetical protein FU22028 670
418555 AI417215 Hs 87159 hypothetical protein FU 12577 667
453102 NM_007197 Hs 31664 fπzzled (Drasophila) homolog 10 662
433615 AA732982 Hs 269607 ESTs, Weakly similar to ALULHUMAN ALU S 662
450638 AK001826 Hs 25245 hypothetical protein FU11269 660
450480 X82125 Hs 25040 zinc finger protein 239 658
445191 AF048686 Hs 12393 dTDP-D-glucose 4,6-dehydratase 656
414575 H11257 Hs 22968 Homo sapienε done IMAGE 451939, mRNA se 654
432630 AW973785 gb EST385886 MAGE resequences, MAGM Homo 654
410116 AW630671 Hs 58636 squamous cell carcinoma antigen recogniz 654
449894 AK001578 Hs 24129 CLLL7 protein 653
442914 AW188551 Hs 99519 hypothetical protein FU14007 653
424745 AA214618 Hs 152759 xtivator of S phase kinase 652
441801 AW242799 Hs 86366 ESTs 652
435542 AA687376 Hs 269533 ESTs 651
427072 H38046 Hs 303193 ESTs 650
418051 AW192535 Hs 19479 ESTs 646
436217 T53925 Hε 107 fibπnogen like 1 646
439809 R41396 Hs 101774 hypothetical protein FU23045 646
430704 AW813091 Hs 335799 ESTs 644
410227 AB009284 Hs 61152 exostoses (multiple) like 2 643
417067 AJ001417 Hs 81086 solute earner family 22 (extraneuronal 641 428382 H10233 Hε.2265 sxretory granule, neuroend∞rine protei 6.40
452198 AI097560 Hs.61210 ESTs, Weakly similar to I38022 hypotheti 6.40
438202 AW169287 Hs.22588 ESTs 6.38
458311 AF069478 gb:AF069478 Homo sapiens astrocytoma lib 6.36
451389 N73222 Hε.279009 matrix Gla protein 6.36
427899 AA829286 Hs.332053 serum amyloid A1 6.35
448693 AW004854 Hs.228320 hypothetical protein FU23537 6.34
425492 AL021918 Hs.158174 zinc finger protein 184 (Kruppel-like) 6.34
435532 AW291488 Hs.117305 Homo sapfens, clone IMAGE:3682908, mRNA 6.32
433908 AW298141 Hs.157975 ESTs 6.32
430114 AA847744 Hs.99640 ESTs 6.32
434032 AW009951 Hs.206892 ESTs 6.31
444656 AI277924 Hs.145199 ESTs 6.30
433607 AA602004 Hs.23260 ESTs 6.26
440659 AF134160 Hs.7327 claudin 1 6.25
435663 AI023707 Hs.134273 ESTs 6.24
400916 BE313625 Hs.57435 solute carrier family 11 (proton-coupled 6.24
436547 AJ297351 Hs.30824 leucine zipper transcription factor-like 6.24
447500 A1381900 Hs.159212 ESTs 6.24
407237 AA169872 Hs.6216 Homo εapiens hepatoceHularcarcinoma-as 6.22
417715 AW86g587 Hs.86366 ESTs 6.22
423276 AC003034 Hs.126261 Homo sapiens Chromosome 16 BAC clone CIT 6.20
438138 R88289 Hs.177502 ESTs 6.20
424590 AW966399 Hs.46821 hypothetical protein FU20086 6.20
416857 AA188775 Hs.292453 ESTs 6.20
427667 AK001279 Hs.180171 Homo sapfens cDNA FU10417 fis, clone NT 6.18
429598 AA811257 Hs.269710 ESTs 6.18
426921 AA037145 Hs.172865 cleavage stimulation fxtor, 3' pre-RNA, 6.18
438940 AF075045 Hs.271609 ESTs 6.18
400195 NA NA 6.15
430473 AW130690 Hs.59962 ESTs 6.12
452291 AF015592 Hs.28853 CDC7 (cell division cycle 7, S. cerevisi 6.10
420096 AA775910 Hs.95011 syntrophin, beta 1 (dystrophin-associate 6.10
427513 AI476318 Hs.192480 ESTs 6.10
448934 AI598134 Hs.225592 ESTs, Highly similar to T51146 ring-box 6.10
410389 AW954049 Hs.8177 ESTs, Weakly similar to PIHUB6 salivary 6.08
430345 AK000282 Hs.239681 hypothetical protein FU20275 6.08
424856 AA347746 Hs.9521 ESTs, Weakly similar to ZN43 HUMAN ZINC 6.08
409048 H59990 Hs.3769g ESTs 6.08
427674 NMJ03528 Hε.2178 H2B histone family, member Q 6.08
452689 F33868 Hs.284176 transferrin 6.06
453804 AA300204 Hs.35276 KIAA0852 protein 6.06
442875 BE623003 Hε.23625 Homo sapiens clone TCCCTA00142 mRNA sequ 6.05
408243 Y00787 Hε.624 interleukin 8 6.04
420721 AA927802 Hs.159471 ZAP3 protein 6.04
420393 AA383024 Hs.201603 Homo sapiens mRNA; cDNA DKFZp434D0917 (f 6.04
435420 AI928513 Hs.59203 ESTs 6.04
428046 AW812795 Hs.155381 ESTs, Moderately similar to I38022 hypot 6.04
407746 AK001962 Hs.38114 hypothetical protein FU11100 6.02
442116 AI884570 Hs.128813 ESTs 6.00
423568 NM 005256 I Hs.129818 growth arrest-spxific 2 6.00
422011 U30246 Hs.110736 solute camerfamily 12 (sodium/cotassi 5.99
441794 AWig7794 Hε.253338 ESTs 5.99
434739 AA804487 Hs.144130 ESTs 5.98
449802 AW901804 Hs.23984 hypothetical protein FU20147 5.96
420218 AW958037 Hs.286 ribosomal protein L4 5.96
425707 AF115402 Hs.11713 E74-like fxtor 5 (ets domain transcript 5.94
445546 AW468821 Hs.156054 ESTs 5.94
439096 AA830185 Hs.269680 ESTs 5.94
452606 N45202 Hs.90012 hypothetical protein FU23441 5.94
427701 AA411101 Hε.243886 nuclear autoantigenic sperm protein (his 5.94
417246 AI760098 Hs.21411 ESTs 5.94
433180 M26901 Hs.3210 renin 5.92
418744 AI887288 Hs.196379 ESTs, Weakly similar to putative p150 [H 5.92
421477 AI904743 Hs.104650 hypothetical protein FU10292 5.92
434342 AI791138 Hs.116768 ESTs 5.92
406668 T62745 Hs.184411 albumin 5.92
418668 AW407987 Hs.173518 M-phase phosphoprotein homolog 5.90
429984 AL050102 Hs.227200 hypothetical protein FU21617 5.90
408867 AA437199 Hs.656 cell division cycle 25C 5.90
409913 BE243842 Hε.283077 centrosomal P4.1-asεxiated protein; uno 5.88
450380 AI863675 Hs.114017 ESTε 5.88
413026 AA809485 Hs.12421 g hypothetical protein FU12934 5.88
454653 AW812227 gb:RC2-ST0173-201099-011-g09 ST0173 Homo 5.87
457876 AI821940 Hs.264622 ESTε, Moderately similar to ALU8 HUMAN A 5.86
437222 AL117588 Hs.12778 ESTs 5.86
455630 AV655701 Hs.75183 cytochrome P450, subfamily HE (ethanol- 5.86
426269 H15302 Hs.168950 Homo sapieπε mRNA; cDNA DKFZp566A1046 (f 5.84
409045 AA635062 Hs.50094 Homo εapieπε mRNA; cDNA DKFZp434O0515 (f 5.84
441645 AI222279 Hε.201555 ESTs, Weakly similar to T23406 hypotheti 5.84
401352 5.84
419088 AI538323 Hs.52620 tntegrin, beta 8 5.84
431379 AA504264 Hs.182937 peptidylpralyl isomerase A (cyclophilin 5.83 438580 AF086401 Hs 293847 ESTε, Moderately similar to S65657 alpha 582
424345 AK001380 Hs 145479 Homo sapiens cDNA FLJ10518 fis, clone NT 582
419220 AA811938 Hs 291759 ESTs 582
439303 W00605 Hs 102784 ESTs 580
415954 AA171850 Hs 42251 ESTs 580
418849 AW474547 Hs 53565 Homo sapiens PIG-M mRNA for mannosyltran 580
429945 NM_006729 Hs 226483 diaphanous (Drasophila homolog) 2 580
430527 AW298119 Hs 202536 ESTs 578
435380 AA679001 Hs 192221 ESTs 578
424086 AI351010 Hs 102267 lysyl oxidase 576
425898 AA36564g Hs 269478 ESTs, Weakly similar to PC4259 femtiπ 576
428460 AA428865 Hs 98563 ESTs 574
416623 N74925 Hs 38761 Homo sapiens cDNA FLJ21564 fis, clone C 574
413982 BE503035 Hs 279193 ESTs 574
453240 AI969564 Hs 166254 hypothetical protein DKFZp566H33 574
410505 AW752139 Hs 314323 ESTs 572
447072 D61594 Hs 17279 tyrosylprotein sulfotransferase 1 572
433312 AI241331 Hs 131765 ESTs, Moderately similar to I38937 DNA/R 572
448966 AW372914 Hs 86149 phoεphoinositol 3-phosphate-bιπdιng prot 571
433384 AI021992 Hs 124244 ESTs 570
415385 R17798 Hs 7535 COBW like protein 570
441884 AA134329 Hs 24170 Homo sapiens, clone IMAGE 3685398 mRNA, 570
414696 AF002020 Hs 76918 Niemann Pick disease, type C1 568
448666 NM 014953 Hs 323346 KIAA1008 protein 568
412246 AI160873 Hs 69233 zinc finger protein 568
426518 Z43039 Hs 170198 KIAA0009 gene product 566
418269 AA806113 Hs 189025 ESTs 564
443316 AI478463 Hs 18443 aldehyde dehydrogenase 8 family, member 564
422805 AA436989 Hs 121017 H2A histone family, member A 562
442252 AI733395 Hs 129124 ESTs 560
414372 AA143654 gb zo65a02 r1 Stratagene pancreas (93720 560
435040 AI932350 Hs 152825 ESTε 559
438777 AA825487 Hs 142179 ESTs 558
433849 BE465884 Hs 280728 ESTs 558
438639 AI278360 Hs 31409 ESTs 558
411274 NM 002776 Hs 69423 kallikrein 10 555
435008 AF150262 Hs 162898 ESTs 555
434194 AF119847 Hs 283940 Homo sapiens PR01550 mRNA, partial eds 554
452881 AW135220 Hs 241921 ESTs 554
426010 AA136563 Hs 1975 hypothetical protein FU21007 554
424492 AI133482 gb HA2093 Human fetal liver cDNA library 554
418971 AA360392 Hs 87113 ESTs 552
453716 AA037675 Hs 152675 ESTs 552
406972 M32053 gb Human H19 RNA gene, complete eds 551
417543 AA203620 Hs 110153 ESTs 551
419423 D26488 Hs 90315 KIAA0007 protein 551
434674 AA831879 Hs 136985 ESTs 550
442980 AA857025 Hs 8878 kinesm like 1 550
418882 NM 004996 i Hs 89433 ATP-binding cassette, sub-family C (CFTR 550
404227 NA NA 549
412766 BE544475 Hs 54347 ESTs 549
441708 AI469911 Hs 26498 hypothetical protein FU21657 549
408432 AW195262 gb xπ67b05 x1 NCI CGAP CML1 Homo sapiens 548
437440 AA846804 Hs 123694 ESTs 548
410486 AW235094 Hs 69233 zinc finger protein 546
456435 AI880384 Hs 270747 ESTs, Weakly similar to ALU2_HUMAN ALU S 544
437378 AI198823 Hs 160473 ESTs 544
436907 AA737171 Hs 131809 ESTs 544
407300 AA102616 gb zn43e07 s1 Stratagene HeLa cell S393 544
413582 AW295647 Hs 71331 hypothetical protein MGC5350 542
441795 N58115 Hs 21137 AD024 protein 542
452449 AW068658 Hs 20943 ESTs 542
439699 AF086534 Hs 187561 ESTs, Moderately similar to ALULHUMAN A 540
431941 AK000106 Hs 272227 Homo sapiens cDNA FU20099 fis, clone CO 540
441217 AI922183 Hs 213246 ESTs 540
432383 AK000144 Hs 274449 Homo sapiens cDNA FU20137 fis, clone CO 540
453891 AB037751 Hε 36353 Homo sapiens mRNA full length insert cDN 540
408690 AW864542 gb PM4-SN0016-120500-003-h02 SN0016 Homo 540
433759 AA680003 Hs 109363 Homo sapienε cDNA. FU23603 fis, clone L 539
446142 AI754693 Hs 145968 ESTs 538
408562 AI436323 Hs 31141 Homo sapiens mRNA for KIAA1568 protein, 536
433829 AI375499 Hs 27379 ESTs 536
421155 H87879 Hs 102267 lysyl oxidase 534
424853 BE549737 Hε 132967 Human EST clone 122887 manner transposo 534
453931 AL121278 Hs 25144 ESTs 534
409091 AW970386 : Hs 269423 ESTs 533
416057 AI927382 Hs 29857 ESTε 533
438647 AA813118 Hs 163230 ESTs 532
415091 AL044872 Hs 77910 3-hydroxy 3-methylglutaryl Coenzyme Asy 532
445038 AI635444 Hs 143917 ' dJ467N11 1 protein 530
408622 AA056060 Hε 202577 ' Homo sapiens cDNA FU12166 fis, clone MA 530
403432 529
435820 AA700580 Hε 18900C I ESTs 528 401714 NA NA 528
448508 AK001566 Hs 23618 hypothetical protein FU10704 528
413151 H47969 Hs 141971 ESTs, Weakly similar to ALULHUMAN ALU S 528
414853 U31116 Hs 77501 sarcoglycan, beta (43kD dystrophm assx 528
417372 T99755 Hs 334728 ESTs 528
443613 AI079356 gb oz39b09 s1 Soares_NhHMPu_S1 Homo sapi 528
412610 Xg0908 Hs 74126 fatty xid binding protein 6, ileal (gaε 527
408843 NM 007070 Hs 49105 FKBP-ass∞iated protein 526
415139 AW975942 Hs 48524 ESTs 526
447982 H22953 Hs 137551 ESTs 526
430789 AA632577 Hs 310235 ESTs, Weakly similar to 178885 seπne/th 524
453821 AI824009 Hs 44577 ESTs 524
409582 R27430 Hs 271565 ESTs 524
420911 U77413 Hs 100293 O linked N-xetylglucosamine (GlcNAc) tr 523
422956 BE545072 Hs 122579 hypothetical protein FU10461 523
418661 NM 001949 Hs 1189 E2F transcnption factor 3 522
446271 D82484 Hs 330994 ESTs 522
435905 AW997484 Hs 5003 KIAA0456 protein 521
434551 BE387162 Hs 280858 ESTs, Highly similar to A35661 DNAexcis 521
415245 N59650 Hs 27252 ESTs 520
436016 AA806465 Hs 121536 Human DNA sequence from clone RP11-472E5 520
431242 AA987742 Hs 251278 KIAA1201 protein 520
439818 AL360137 Hs 19934 Homo sapiens mRNA full length insert cDN 520
424281 AA766243 gb oa13b11 s1 NCI CGAP GCB1 Homo sapiens 520
449138 AW294215 Hs 195631 ESTs 520
449416 AI651016 Hs 246311 ESTs 520
430092 AI821388 Hs 16514 ESTs 520
436574 AW283527 Hs 126465 ESTs 518
433377 AI752713 Hs 43845 ESTs 518
440987 AA911705 Hs 130229 ESTs 518
426116 AA868729 Hs 144694 ESTs 518
441928 AI370188 Hs 211454 ESTs 517
432657 AA831815 Hs 270940 ESTs, Weakly similarto I78885 seππe/th 5 17
438011 BE466173 Hs 145696 splicing fxtor (CC1 3) 516
437257 AI283085 Hs 290931 ESTs, Weakly similar to YFJ7_YEAST HYPOT 516
423926 X03833 Hs 1722 interleukin 1, alpha 516
433393 AF038564 Hs 98074 itchy (mouse homolog) E3 ubiquitin prate 515
415757 AA830854 Hs 187810 ESTs 514
420170 U43374 Hs 95631 Human normal keratin∞yte mRNA 514
420493 AI635113 Hs 270366 ESTs, Weakly similarto I78885 seπne/th 512
425739 T19016 Hs 159410 molybdopteππ synthase sulfurylase 512
440652 AI216751 Hs 143977 ESTs 512
419706 C04649 Hs 77899 tropomyosin 1 (alpha) 512
427728 AJ245600 Hs 180545 Homo sapiens mRNA for hypothetical prate 5 12
416113 AA173525 Hs 118758 ESTs, Weakly similar to RLF [H sapiens] 512
446223 BE300091 Hs 119699 hypothetical protein FU 12969 511
407624 AW157431 Hs 248941 ESTs 511
447197 R36075 gb yh88b01 s1 Soares plxenta Nb2HP Homo 511
452465 AA610211 Hs 34244 ESTs 5 10
442833 AA328153 Hs 88201 ESTs, Weakly similar to A Chain A, Cryst 510
448952 AI609595 Hs 208038 ESTs 510
408170 AW204516 Hs 31835 ESTs 508
424238 AA337401 Hs 137635 ESTs 507
421072 AI215069 Hs 89113 ESTs 506
424717 H03754 Hs 152213 wingleεs-type MMTV integration εite fami 506
423654 AI674253 Hs 35828 ESTε 506
436862 AI821940 Hs 264622 ESTs, Moderately similar to ALU8_HUMAN A 506
436554 AI985810 Hs 301173 ESTs 505
433264 D85782 Hs 3229 cysteine dioxygenase, type I 504
452387 AI680772 Hε 306094 tπnucleotide repeat containing 12 504
412666 AL080116 Hs 74420 oπgin recognition complex, subunit 3 (y 503
430287 AW182459 Hs 125759 ESTs, Weakly similarto LEU5_HUMAN LEUKE 503
413293 AL047483 Hs 302498 GTP-biπdmg protein homologous to Sxoha 500
418217 AI910647 Hs 13442 ESTs 500
401480 NA NA 500
456179 H75490 Hs 271930 ESTs 500
TABLE 7B Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT number Accession
408432 1058667 1 AW195262 R27868 AW811262
408690 107490 1 AW864542 AA056567 AW882724
411765 125700 1 H43346 AA248302 AA095182
414372 143900 1 AA143654 AW753140 AA213770 AW070865 AA568075 AA492132
424281 237742 1 AA766243 AA338252 AA338213 424492 240008 1 AI133482 AI207619 AA341626
428679 294049 1 AA431765 AA432015
430848 324621 1 AW021726 AA487752 AA488085
432340 345248 1 AA534222AA632632T81234
432363 345469 1 AA534489 AW970240 AW970323
432639 351744 1 AW973785 H60163 AA557608
434609 38950 1 R76593AF147390 R76594
439518 47334 1 W76326AF086341 W72300
443613 575391 1 AI079356W23287
447197 711623 1 R36075 AI366546 R36167
447974 745643 1 R76886 AI453674 R77049
452712 928309 1 AW838616 AW838660 BE144343 AI914520 AW888910 BE184854 BE184784
454653 122808Ϊ 1 AW812227 AW812294 AW812092
458311 543550 ϊ AF069478 AF06947g AF069480
TABLE 7C
Pkey: Unique number corresponding to an Eos probeset Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489-495. Strand: Indicates DNA strand from which exons were predicted.
NLpoεition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand N position
400534 6981826 Minus 278637-279292
401352 9931258 Minus 26064-26208
401480 7321503 Plus 166120-166347,166451-166557, 169651-169832
401714 6715702 Plus 96484-96681
401742 2911728 Plus 64003-64147
403432 9719611 Minus 68204-68392
403776 7770611 Minus 1414-1513,1624-1756
404227 7838233 Minus 93110-93259
404567 7249169 Minus 101320-101501
404996 6007890 Plus 37999-38145,38652-38998,39727-39872,40557-40674,42351-42450
406360 9256107 Minus 7513-7673
Table 8A shows 538 genes significantly down-regulated in colon cancer compared to normal colon. These were selxted as for Table 7A and the ratio was equal to or less than than 0.33.
TABLE 8A: 538 GENES SIGNIFICANTLY DOWN-REGULATED IN COLON CANCER COMPARED TO NORMAL COLON
Pkey: Unique Eos probeset identifier number
ExAccn: Exemplar A∞esεion number, Genbank acceεεion number
UnigenelD: Unigene number
Unigene Title: Unigene gene title
R1: Ratio of tumor to normal colon
Pkey ExAccn UnigenelD Unigene Title R1
421996 AW583807 Hs.1460 glucagon 0.0233
429970 AK000072 Hs.227050 chloride channel, calcium activated, fam 0.0307
457407 AA505035 Hs.195651 ESTs 0.0416
423690 AA329648 Hs.23804 ESTs, Weakly similar to PN0099 son3 prot 0.0564
426651 AU076646 Hε.171683 nuclear rxeptor subfamily 1, group H, m 0.0567
425020 AL049977 Hs.162209 claudin 8 0.0601
431436 AA505035 Hs.195651 ESTs 0.0607
433084 M18079 Hs.282265 fatty xid binding protein 2, intestinal 0.0629
442008 AI733281 Hs.128320 ESTs 0.0634
416889 AW250318 Hs.80305 mal, T-cell differentiation protein 0.0707
429050 X81333 Hs.194777 meprin A, beta 0.0714
427019 AA001732 Hs.173233 hypothetical protein FU 10970 0.0735
446947 AF146747 Hs.232165 polycythemia rubra vera 1; cell surface 0.0739
429657 D13626 Hs.2465 KIAA0001 gene product; putative G-protei 0.0769
443506 H10661 Hs.192124 ESTs, Weakly similarto I38022 hypotheti 0.0838
415314 N88802 Hs.5422 glycoprotein M6B 0.0853
451181 AI796330 Hs.207461 ESTε 0.0873
429001 AF098951 Hs.194720 ATP-binding cassette, sub-family G (WHIT 0.0888
426635 BE395100 Hs.129327 hypothetical protein MGC13057 0.0900
429350 AI754634 Hs.131987 ESTs 0.0927
432251 AW972983 Hs.232165 polycythemia rubra vera 1 ; cell surface 0.0931 411529 AA430348 Hs 317596 Homo sapiens cDNA FU12927 fis, clone NT 00951
441066 AW205427 Hs 190726 ESTs, Weakly similar to ALULHUMAN ALU S 00957
431252 NM 005478 Hs 251380 insulin like 5 00985
437090 N77793 Hs 48659 ESTs, Highly similar to S14458 laminin a 00987
433546 AI075877 Hs 125461 hypothetical protein FU11539 0 1007
415154 D63175 gb HUM501B09B Clontxh human placenta po 0 1032
409921 AW600239 gb EST00009 pGEM-T library Homo sapiens 0 1067
432440 X63597 Hs 2996 sucrase-isomaltase 0 1107
430468 NM 04673 Hs 241519 angiopoietin like 1 0 1114
427167 AI239607 Hs 99196 hypothetical protein MGC11324 0 1147
441212 AW242447 Hs 146182 cytosolic beta-glucosidase 0 1167
423605 AF047826 Hs 129887 cadhenn 19, type 2 0 1190
411381 AW841862 Hs 306831 Homo sapiens cDNA FU22549 fis, clone H 0 1211
412639 AW961284 Hs 296235 ESTs 0 1239
453399 Z70295 Hs 32966 guanylate cyclase xtιvator2B (uroguaπy 0 1240
403548 0 1248
421913 AI934365 Hs 109439 osteoglycm (osteoinductive fxtor, mime 0 1274
457982 AW856093 Hs 183617 ESTs 0 1277
448835 BE27792g Hs 11081 UBX domain-containing 2 0 1277
431292 AA370141 Hs 2281 chromograπin B (sxretogranin 1) 0 1291
441805 AA285136 Hs 301914 neuronal εpxific transcnption fxtor D 0 1309
407639 AW205360 Hs 312830 ESTs 0 1315
421741 AK001879 Hs 107527 hypothetical protein FU11017 0 1325
4547gθ AW820852 gb RC2-ST0301-120200-011-f12 ST0301 Homo 0 1328
451742 T77609 Hs 117970 ankyπn 2, neuronal 0 1335
425849 AJ000512 Hs 296323 serum/gluc∞orticoid regulated kinase 0 1379
411880 AW872477 gb hm30f03 x1 NCI_CGAP_Thy4 Homo sapiens 0 1393
416585 X54162 Hs 79386 leiomodm 1 (smooth muscle) 01395
435868 AF255910 Hs 54650 junctional adhesion molecule 2 0 1456
407744 AB020629 Hs 38095 ATP-binding cassette, sub-family A (ABC1 0 1459
404767 0 1460
407266 AJ235664 gb Homo sapiens mRNA for immunoglobulin 0 1462
427359 AW020782 Hs 79881 Homo sapiens cDNA FU23006 fis, clone L 0 1463
452768 AW068459 Hs 61539 ESTs 0 1466
418692 AK000268 Hs 87383 hypothetical protein 0 1471
414831 M31158 Hs 77439 protein kinase, cAMP dependent, regulato 0 1471
407551 Y10516 gb H sapiens mRNA for CD58 T3 protein 0 1486
402076 0 1487
453500 AI478427 Hs 43125 esophageal cancer related gene 4 protein 0 1500
442080 AW444761 Hs 44565 ESTs 0 1500
431706 AI816086 Hs 296341 adenylyl cyclase-ass∞iated protein 2 0 1513
429545 AI824164 Hs 77667 lymphocyte antigen 6 complex, tocus E 0 1523
418390 AF133820 Hs 84665 titin immunoglobulin domain protein (myo 0 1529
435056 AW023337 Hs 5422 glycoprotem M6B 0 1532
426034 AI276989 Hs 56123 Homo sapiens cDNA FU13443 fis, clone PL 0 1538
429609 AF002246 Hs 210863 cell adhesion molecule with homology to 0 1542
408221 AA912183 Hs 47447 ESTs 0 1552
425220 AW975317 Hs 162987 ESTs 0 1558
445200 AA084460 Hs 12409 somatostatin 0 1558
443238 T78886 Hs 284450 ESTs 0 1563
456064 AA256213 Hs 72010 ESTs 0 1582
428133 AW167727 Hs 11873 ESTs 0 1605
447261 NM_006691 Hs 17917 extracellular link domain-containing 1 0 1615
437734 AA693951 Hs 180284 ESTs 01637
414290 AI568801 Hs 71721 ESTs 0 1638
418935 T28499 Hs 89485 carbonic anhydrase IV 0 1656
411939 AI365585 Hs 146246 ESTs 0 1660
442496 R55073 Hs 124130 ESTs 0 1676
450693 AW450461 Hs 203965 ESTs 01698
420736 AI263022 Hs 82204 ESTs 0 1718
405385 01745
404638 0 1751
427333 AF067797 Hs 176658 aquapoπn 8 0 1757
404246 01763
433785 BE044593 Hs 112704 ESTs 01767
412056 T28160 Hs 778 guanylate cyclase xtivator 1B (retina) 0 1769
406980 S69265 (NONE) 01781
421666 AL035250 Hs 1408 endothelin 3 0 1784
452854 AA437061 Hs 14060 prokineticm 1 precursor 01795
400514 0 1805
454186 BE141030 gb MRO-HT0067-201099 002-hU HT0067 Homo 0 1808
410765 A1694972 Hs 66180 nucleosome assembly protein 1-lιke 2 01812
413724 AA131466 Hs 23767 hypothetical protein FU12666 0 1812
412474 AI791451 gb nι50c09 y5 NCI CGAP Ov2 Homo sapiens 0 1812
436008 AI078428 Hs 58785 ESTs 01820
423424 AF150241 Hs 128433 prostaglandm D2 synthase, hematopoietic 0 1828
431728 NMJ07351 Hs 268107 mullimenn 0 1832
419746 AW867943 I Hs 127216 hypothetical protein FU13465 01835
410677 NM_003278 Hs 65424 tetranxtin (plasminogen binding protein 0 1838
415672 N53097 Hs 183579 ESTs 0 1838
419050 NM 000036 Hs 89570 adenosine monophoεphate deammaεe 1 (iso 01838
417342 W40277 Hs 81994 glycophoπn C (Gerbich blood group) 0 1842
413714 AI560944 Hs 71428 ESTs 0 1845 427061 AB032971 Hs.173392 KIAA1145 protein 0.1847
405282 0.1848
400163 0.1855
412295 AW088826 Hs.117176 poly(A)-binding protein, nuclear 1 0.1863
447414 D82343 Hs.18551 neurablastoma (nerve tissue) protein 0.1876
407891 AA486620 Hs.41135 endomucin-2 0.1895
437140 AA312799 Hs.283689 xfivator of CREM in testis 0.1901
431544 AK000770 Hε.298329 Homo sapiens cDNA FLJ20763 fis, clone CO 0.1904
436659 AI217900 Hε.144464 ESTs 0.1905
447164 AF026941 Hs.17518 Homo sapiens cig5 mRNA, partial sequence 0.1926
453698 AA037615 Hs.42746 ESTs 0.1928
423743 AB023148 Hs.173373 KIAA0931 protein 0.1941
428412 AA428240 Hs.126083 ESTs 0.1942
420058 AK001423 Hs.946g4 Homo sapiens cDNA FU10561 fis, clone NT 0.1944
434683 AW298724 Hs.202639 ESTs 0.1957
421865 AA609911 Hs.109012 MAX dimerization protein 0.1957
452786 R61362 Hs.106642 ESTs, Weakly similar to T09052 hypotheti 0.1969
407601 AC002300 Hs.37129 sodium channel, nonvoltage-gated 1, beta 0.1981
419758 U31973 Hs.93173 phoεphodieεterase 6C, cGMP-specific, con 0.2004
437740 AA810265 Hs.122915 ESTs 0.2016
405610 0.2017
437145 AF007216 Hs.5462 solute camerfamily 4, sodium bicarbon 0.2025
416961 BE391476 Hs.80617 ribosomal protein S16 0.2041
401465 0.2045
437425 AW183714 Hs.20981 hypothetical protein DKFZp547M236 0.2049
416231 H30333 Hs.165062 ESTs 0.2049
401753 0.2050
433430 AI863735 Hs.186755 ESTs 0.2051
432150 AK000224 Hs.272789 hypothetical protein FU20217 0.2052
411644 H92064 Hs.278626 Arg/Abl-interxting protein ArgBP2 0.2059
403957 0.2063
435900 AI243036 Hs.16094 ESTs 0.2070
424208 AW583123 Hs.143113 pancreatic lipase-related protein 2 0.2075
445500 AW451938 Hs.257512 ESTs 0.2075
419956 AL137939 Hs.40096 ESTs 0.2090
418026 BE379727 Hs.83213 fatty xid binding protein 4, adipocyte 0.2093
423655 AA722425 Hs.182785 ESTs, Moderately similarto 1207289A rev 0.2118
401381 0.2120
426452 AW614271 Hs.121647 ESTs, Highly similarto AC0060148 simil 0.2122
433476 AA594394 Hε.152616 ESTs 0.2125
423405 NM 14151 Hs.128155 HSPC053 protein 0.2130
442826 AI018777 Hs.131241 ESTs 0.2132
427060 AW378993 Hs.90286 ESTs 0.2137
437354 AA749215 Hs.291886 ESTs 0.2137
447734 AI421412 Hs.163659 ESTs 0.2144
424585 AA464840 Hs.131987 ESTs 0.2146
458016 AW18809g Hε.131813 ESTs 0.2151
423893 AL031709 Hs.134846 Human DNA sequence from clone 316G12 on 0.2151
401521 0.2157
430130 AL137311 Hs.234074 Homo sapiens mRNA; cDNA DKFZp761 G02121 ( 0.2165
401024 0.2171
414802 AI793107 Hs.27018 Ris 0.2179
441083 BE562611 gb:601336446F1 NIH_MGC_44 Homo sapiens c 0.2185
417355 D13168 Hs.82002 endothelin rxeptor type B 0.2186
422440 NM 004812 I Hs.116724 aldo-keto reductase family 1 , member B10 0.2188
442930 AW881975 Hs.213923 ESTs 0.2193
431089 BE041395 Hε.283676 ESTs, Weakly similar to unknown protein 0.2209
444567 AV654020 Hs.184261 ESTs, Weakly similar to T26686 hypotheti 0.2212
405654 0.2217
415471 F09747 Hs.268707 ESTs 0.2222
449243 AW295031 Hs.188671 ESTs 0.2229
436088 AA704687 Hs.191294 ESTs 0.2232
434098 AA625499 gb:af69g08.r1 Soares_NhHMPu_S1 Homo εapi 0.2242
427552 NM_00577- I Hs.179608 retinol dehydrogenase homolog 0.2243
416439 AA180363 Hs.118769 ESTs 0.2244
459390 BE385725 gb:601276347F1 NIH MGC 20 Homo sapiens c 0.2254
459395 Z30300 Hε.281935 ESTs 0.2257
439039 AI656707 Hs.48713 ESTs 0.2268
433575 AA600175 Hs.39720 ESTs 0.2268
416035 H42314 gb:yo09e02.s1 Soares adult brain N2b5HB5 0.2273
428415 AA337211 Hs.184222 Down syndrome critical region gene 1 0.2283
441899 AI372588 Hs.8022 TU3A protein 0.2283
437191 NMJ06846 Hs.331555 serine protease inhibitor, Kazal type, 5 0.2290
434839 AI743069 Hs.134736 ESTs 0.2294
435731 AA699581 Hs.186811 ESTs 0.2299
400865 0.2304
446294 AI284935 gb:qk55g09.x1 NCI CGAP Co8 Homo sapienε 0.2305
414193 BE260069 gb:601150964F1 NIH MGC 19 Homo εapieπs c 0.2309
411514 AW850178 gb:IL3-CT0219-271099-022-H12 CT0219 Homo 0.2315
453098 Z25935 Hε.86379 ESTs 0.2315
430378 Z29572 Hε.2556 tumor nxrosiε fxtor rxeptor εuperfami 0.2319
432374 W68815 Hs.301885 Homo εapiens cDNA FU11346 fis, clone PL 0.2320
443482 AW188093 I Hs.250385 ESTs 0.2326 432134 AI816782 Hs 122583 hypothetical protein FU21934 02320
421539 AA292747 Hs 97296 ESTs 02330
448520 AB002367 Hs 21355 doublxortin and CaM kinase like 1 02344
408001 AA046458 Hs 95296 ESTs 02347
409331 M36634 Hs 53973 vasoxtive intestinal peptide 02351
431094 AW972276 Hε 116195 ESTs 02354
42g575 AA706003 Hs 99387 ESTs 02358
404958 02361
439731 AI953135 Hs 45140 hypothetical protein FU14084 02364
452742 AW589945 Hs 97876 hypothetical protein DKFZp564K0322 02380
417511 AL049176 Hs 82223 chordin like 02381
404027 02387
430207 AW243166 Hs 129806 ESTs 02412
447482 AB033059 Hs 18705 KIAA1233 protein 02415
418332 R34976 Hs 78293 ESTs 02416
454145 AA046872 Hs 62798 ESTs 02421
422472 R59096 Hs 279939 mitochondπal earner homolog 1 02424
404070 02427
421232 AA989220 Hs 292100 ESTs 02427
414539 BE379046 gb 601236646F1 NIH MGC 44 Homo sapiens c 02432
412622 AW664708 Hs 171959 ESTs 02433
454430 AI082777 Hs 61384 sema domain, εeven thrombospondin repeat 02437
416694 AW161284 Hs 79564 neuronal PAS domain protein 1 02443
426724 AA383623 Hs 293616 ESTs 02444
405073 02445
401236 H24185 Hs 92918 hypothetical protein 02445
414203 BE262170 Hs 78629 ATPase, Na+/K+ transporting, beta 1 poly 02451
401776 02452
404696 02462
426666 AW500131 Hs 171763 CD22 antigen 02471
427078 AI676062 Hs 111902 ESTε 02474
424682 AW604804 Hs 151717 KIAA0437 protein 02478
440383 AA884208 Hs 30484 ESTs 02481
419118 AA234223 Hs 139204 ESTs 02494
443515 AV657547 Hs 286014 Homo sapiens, clone IMAGE 3867243, mRNA 02495
424648 AA344576 gb EST50478 Gall bladder I Homo sapienε 02499
404605 02500
446066 A1343931 Hs 149383 ESTε 02505
408345 R93851 Hs 63063 ESTs 02506
418358 L02840 Hs 84244 potassium voltage-gated channel, Shab-re 02508
416950 AL049798 Hs 80552 dermatopontin 02510
423555 AW958201 Hs 178589 hepatocellular carcinoma antigen gene 52 02513
449833 R82252 Hs 106106 protein kinase (cAMP-dependent catalyti 02515
459275 AI808913 Hs 339352 Homo sapiens brother of CDO (BOC) mRNA, 02519
406897 M57417 gb Homo sapiens mucin (mucin) mRNA, part 02523
422743 BE304678 Hs 119598 πbosomal protein L3 02526
459688 U72671 Hs 151250 intercellular adhesion molxule 5, telen 02532
450880 AK002183 Hs 285885 Homo sapienε cDNA FU11321 fis, clone PL 02536
457330 AB013818 Hs 247220 peroxisome biogenesiε fxtor 10 02536
451979 F06972 Hs 27372 BMX non-receptor tyrosine kinase 02549
440274 R24595 Hs 7122 scrapie reεponεive protein 1 02553
430097 AI523245 Hs 127638 ESTs 02558
410626 BE407727 gb 601299771F1 NIH_MGC_21 Homo sapiens c 02564
402695 02565
453992 AW014995 Hs 281080 ESTs 02569
453888 AW450670 Hε 252819 ESTs 02569
401371 02574
456145 BE28g427 Hε 21446 KIAA1716 protein 02579
408134 AK000184 Hε 42945 xid sphingomyelinase-like phosphodieste 02580
422591 L07648 Hs 118630 MAX-interacting protein 1 02582
452359 BE167229 Hs 29206 hypothetical protein MGC14376 02584
447569 A1393202 Hs 147554 hypothetical protein FU23392 02586
405880 02588
420321 D78761 Hs 96657 hyothetical protein 02595
454415 AK000846 Hs 58679 solute earner family 7, (cationic ammo 02602
437032 AW867372 Hs 302063 immunoglobulin heavy constant mu 02604
448025 BE502965 Hs 170426 ESTs 02605
444304 AW628433 Hs 271296 ESTs, Weakly similar to I54374 gene NF2 02605
424885 AI333771 Hs 82204 ESTs 02608
425381 D84371 Hs 1898 paraoxonase 1 02611
457413 AA743462 Hs 165337 ESTε 02618
452078 AA022620 Hs 52170 ESTs 02624
450785 AA852713 Hs 25459 Homo sapiens, alpha-1 (VI) collagen 02628
401974 02639
411319 BE537094 gb 601063333F1 NIH MGC 10 Homo sapiens c 02646
417761 R13727 Hs 21435 ESTs 02648
426132 AA370501 gb EST82261 Prostate gland I Homo sapien 02653
455771 BE084820 Hs 186711 hypothetical protein FU20070 02653
414349 BE512968 gb 601172296F1 NIH_MGC_15 Homo sapiens c 02660
402182 02660
402610 02661
444814 BE010749 Hs 255097 ESTs 02663
450017 W56434 Hs 201608 ESTs 02663 408684 R61377 Hs.12727 hypothetical protein FLJ21610 0.2667
444208 AI753134 Hs.146494 ESTs 0.2668
415022 X59960 Hs.77813 sphingomyeliπ phosphodiesterase 1 , xid 0.2677
416184 R48481 Hs.269177 ESTs, Weakly similar to ALU6_HUMAN ALU S 0.2681
422909 AA533356 gb:nj67f10.s1 NCI CGAP_Pr10 Homo sapiens 0.2681
412047 AA934589 Hs.49696 ESTs 0.2693
426356 BE536836 Hs.98682 hypothetical protein FKSG32 0.2703
442238 AW135374 Hs.270849 ESTs, Moderately similar to F41925 hypot 0.2709
402425 0.2710
450545 AW135582 Hε.201767 ESTs 0.2710
417118 U38654 Hε.50477 RAB27A, member RAS oncogene family 0.2725
419850 F06844 gb:HSC1ME091 normalized infant brain cDN 0.2727
428020 L19058 Hs.181581 glutamate receptor, ionotropic, kainate 0.2730
441493 AW070446 Hs.127037 ESTs 0.2733
413541 BE147036 gb:QV4-HT0222-091199-024-e10 HT0222 Homo 0.2733
428470 AC002301 Hs.184507 Homo sapiens Chromosome 16 BAC clone CIT 0.2734
455597 BE008545 Hs.156110 immunoglobulin kappa constant 0.2740
447809 AW207605 Hs.164230 ESTs, Highly similar to JC72663',5'-oyc 0.2740
444195 AB002351 Hs.10587 KIAA0353 protein 0.2743
415160 T82802 gb:yd38a04.r1 Soares fetal liver spleen 0.2747
421823 N40850 Hs.28625 ESTs 0.2755
434464 BE063921 Hs.295971 ESTs 0.2755
414376 BE393856 Hs.66915 ESTs, Weakly similarto 16.7Kd protein [ 0.2756
430073 U86136 Hs.232070 telomerase-assxiated protein 1 0.2762
432018 AA524447 Hε.152377 ESTs 0.2763
422954 AW998605 gb:PMO-BN0065-100300-001-b10 BN0065 Homo 0.2768
416397 H53035 Hs.337620 Homo sapiens AFG3L1 isoform 1 mRNA, part 0.2775
442420 AI024834 Hs.131729 ESTs 0.2775
410950 AW811633 gb:RC2-ST0158-091099-011-d05 ST0158 Homo 0.2778
427114 AI219896 Hs.97592 ESTs 0.2778
448466 AI522109 Hs.171066 ESTs 0.2778
434445 AI349306 Hs.11782 ESTs 0.2784
457115 AA420712 gb:nc63c07.ε1 NCI_CGAP_Pr1 Homo sapiens 0.2785
459511 A1142379 gb:qg64c01.r1 Soares_teεtis_NHT Homo sap 0.2786
421321 NM 005309 Hs.103502 glutamic-pyruvate traπsaminase (alanine 0.2794
433633 AI880516 Hs.84630 ESTs, Weakly similar to 2004399A chromos 0.279g
440236 AW996722 Hs.125297 ESTε 0.2799
405691 0.2804
405334 0.2804
403047 0.2809
412506 AW957159 gb:EST369229 MAGE reεequences, MAGD Homo 0.2809
441042 AA077736 gb:7B48A07 Chromosome 7 Fetal Brain cDNA 0.2815
434660 AA764768 Hs.121158 hypothetical protein DKFZp434J0113 0.2816
444453 AW379394 Hs.145126 ESTs 0.2817
457736 AK000390 Hs.4205 hypothetical protein FU20124 0.2820
454012 M76424 Hs.37014 carbonic anhydrase VII 0.2821
427448 BE246449 Hs.2157 Wiskott-Aldrich syndrome (xzema-thrombo 0.2822
419564 U08989 Hs.91139 solute carrier family 1 (neuronal/epithe 0.2827
435021 AA922192 Hs.54709 ESTs 0.2828
413344 U46024 Hs.75302 yotubular myopathy 1 0.2837
447787 BE620108 gb:601483015F1 NIH MGC_69 Homo sapiens c 0.2840
457290 AA465293 Hs.1O5069 ESTs 0.2841
458244 AI929453 Hs.122489 Homo sapiens cDNA FU13289 fis, clone OV 0.2841
437483 AL390174 gb:Homo sapiens mRNA; cDNA DKFZp547J184 0.2842
407938 AA905097 Hs.85050 phospholamban 0.2845
417332 AW972717 Hs.288462 hypothetical protein FU21511 0.2846
428212 AW444451 Hs.134812 ESTs 0.2853
424433 H04607 Hs.9218 ESTs 0.2857
425195 AA352026 Hs.94319 VPS10 domain receptor protein 0.2857
404769 0.2863
411620 AW854536 gb:RC3-CTO255-20010O-O24-a08 CT0255 Homo 0.2868
428746 AW503820 Hs.192861 Spi-B transcription fxtor (Spi-1 PU.1 r 0.2870
431822 AA516049 gb:ng65d01.s1 NCI_CGAP_Lip2 Homo sapiens 0.2872
441290 W27501 Hs.89605 cholinergic receptor, nicotinic, alpha p 0.2874
422033 AW245805 Hs.110903 claudin 5 (transmembrane protein deleted 0.2877
421935 AA131632 Hs.109672 CMP-NeuAC:(beta)-N-xetylgalxtosaminide 0.2878
447955 BE544271 Hs.288390 hypothetical protein FU22795 0.2880
405364 0.2881
422165 AL041199 Hs.1481 histidine decarboxylase 0.2882
431087 H12723 Hs.290791 ESTs 0.2882
450610 AA010370 Hs.60386 nuclear RNA export fxtor 3 0.2882
445627 AW818475 Hs.7363 ESTs 0.2883
436144 AW881250 Hs.148367 ESTs 0.2886
445152 AI214667 Hs.283597 ESTs 0.2891
430304 AL122071 Hs.238927 Homo sapfens mRNA; cDNA DKFZp434H1235 (f 0.2891
455614 AI693369 Hs.202274 ESTs 0.2899
419683 AA248897 Hs.48784 ESTs 0.2900
411886 AL046810 Hs.20021 vesicle-associated membrane protein 1 (s 0.2004
430770 AA765694 Hs.123296 ESTε 0.2913
444459 AI680624 Hs.148676 ESTs 0.2913
444918 AI202262 Hs.283362 ' ESTs 0.2915
410845 AW807182 gb:MR4-ST0062-180200-001-b04 ST0062 Homo 0.2915
435598 AA689470 Hs.163026 ESTs 0.2921 413056 BE063031 gb MRO-BT0265-231199-002 e09 BT0265 Homo 02922
443998 AI620661 Hs 286276 ESTs 02924
424412 H15512 Hs 10043 hypothetical protein FU13074 02925
421204 AW081587 Hs 165051 ESTs 02928
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 02938
440507 H06994 gb yl81b07 r1 Soares infant brain 1NIB H 02943
445555 AW974013 Hs 260800 ESTs 02945
438570 AW888554 Hs 84298 CD74 antigen (invariant polypeptide of m 02948
447195 T73745 Hs 279870 ESTs, Weakly similar to A46010 X linked 02950
423267 AL137416 Hs 126177 Homo sapiens mRNA cDNA DKFZp4340192 (fr 02956
421920 BE551245 Hs 1438 gamma ammobutyπc xid (GABA) rxeptor, 02956
412177 Z23091 Hs 73734 glycoprotein V (platelet) 02959
428042 AA41952g Hs 76391 yxovirus (influenza) reεiεtance 1, homo 02959
433745 AF075320 Hs 28980 hypothetical protein FLJ14540 02969
417935 R53697 Hs 170044 ESTs 02970
420674 NM 000055 Hs 1327 butyrylcholinesterase 02973
413537 BE146866 gb QV4-HT0222-211099 014-RJ6 HT0222 Homo 02973
445194 AI215667 Hε 175044 ESTs 02974
454135 AW135965 Hs 246783 ESTs 02976
403418 02986
457605 AV657778 Hs 3314 selenopratein P, plasma 1 02989
408896 AI610447 Hs 48778 niban protein 02993
448542 BE256176 Hs 278712 eukaryotic translation initiation fxtor 02994
417945 R29072 gb F1-101D 22 week old human fetal liver 02994
412518 BE047637 Hs 173739 hypothetical protein FLJ 10297 02996
424566 M16801 Hs 1790 nuclear rxeptor subfamily 3, group C m 02997
430778 D90337 Hs 247916 natnuretic peptide precursor C 03000
451531 AA018311 Hs 114762 ESTs 03003
444926 AI202492 Hs 212933 ESTs, Weakly similar to CLD4JHUMAN CLAUD 03003
407366 AF026942 gb Homo sapienε cιg33 mRNA, partial εequ 03012
459456 AA486036 Hs 190124 ESTs 03012
417111 AW016321 Hs 82306 destπn (xtin depolymenzing fxtor) 03012
452975 M85521 Hs 244482 Homo sapiens, clone IMAGE 3611719, mRNA, 03012
451959 AA056203 Hs 27337 hypothetical protein FU20623 03012
410482 AW772187 Hs 191859 ESTs 03013
417700 M36542 Hs 1101 POU domain, class 2, transcnption fxto 03018
404414 03019
432247 AA531287 Hs 105805 ESTs 03023
453471 AL037887 Hs 208179 ESTs 03028
417481 AA203281 Hs 21798 ESTs 03029
432306 Y18207 Hs 303080 pratem phosphatase 1, regulatory (mhib 03032
448744 AL135424 Hs 9469 plxkstπn homology domain-containing, f 03033
429223 BE264152 Hε 221994 ESTs 03034
404501 AW247252 Hs 75514 nucleoside phosphorylaεe 03037
406829 AW419128 Hs 84298 CD74 antigen (invaπant polypeptide of m 03039
438839 AW297945 Hs 128490 ESTs 03039
431848 AI378857 Hs 126758 ESTs, Highly similar to AF175283 1 zinc 03042
456373 BE247706 Hs 89751 membrane-spanning 4-domaιns, subfamily A 03045
458789 AL157468 Hs 325825 Homo sapienε cDNA FU20848 fis, clone AD 03048
443294 AI733625 Hs 133053 ESTs 03050
447023 AA356764 Hs 17109 integral membrane protein 2A 03052
458583 AI479646 Hs 157081 hypothetical protein MGC4170 03056
414567 BE281057 Hs 184519 hypothetical protein FU 12949 03057
445123 AI762911 Hs 145369 ESTs 03064
412682 AW983772 gb RC3-HN0002-060400-012-h09 HN0002 Homo 03065
434361 AF129755 Hs 117772 ESTs 03071
414026 BE241713 gb TCAAP1E0472 Pediatπc xute yelogeno 03072
432149 AW614326 Hs 157022 ESTs, Weakly similar to T34549 probable 03073
408350 AW183350 Hs 250127 ESTs 03074
401042 03077
422586 AA312704 Hs 59457 hypothetical protein FU22127 03077
438692 AB007950 Hs 6360 KIAA0481 gene product 03077
447452 BE618258 Hs 102480 Homo sapiens, clone IMAGE 3869590, mRNA, 03083
444414 AW293214 Hs 8752 transmembrane protein 4 03085
422373 AK001843 Hs 115700 Homo sapiens cDNA FLJ23515 fis, clone L 03088
430410 AFoggw Hs 250700 tryptase beta 1 03090
419299 AI311085 Hs 62406 hypothetical protein FU22573 03091
400672 03094
444010 AW876457 Hs 282887 ESTs 03096
451699 AL118571 Hs 121557 ESTs, Weakly similar to DPLHUMAN POLYPO 03096
432471 BE244667 Hs 296155 CGI-100 protein 03105
405277 03106
456765 AI497900 Hs 33067 ESTs 03106
452090 AA022684 Hs 124673 Homo sapiens cDNA FU11477 fis, clone HE 03106
426497 AA379913 gb EST92807 Skin tumor I Homo sapiens cD 03106
406592 03106
423621 BE002904 gb QV4-BN0090-070400-163-C07 BN0090 Homo 03107
417919 AI928203 Hs 86379 ESTs 03110
414484 BE314385 gb 601154649F1 NIH_MGC_19 Homo sapienε c 03110
457439 AW410408 Hs 271167 L-pipxolic xid oxidase 03116
426449 AL134009 Hs 169936 Homo sapiens mRNA, cDNA DKFZp586N1918 (f 03116
419942 U25138 Hs 93841 potassium large conductance calcium acti 03119
458544 AI631036 Hs 196843 ESTs 03119 447778 BE620592 Hs.71190 ESTs, Weakly similar to S16506 hypotheti 0.3121
448007 BE271708 Hs.95110 ESTs, Weakly similar to A559431-phospha 0.3125
429338 AW170591 Hs.13967 ESTε, Weakly similar to PSM_HUMAN PROSTA 0.3125
451385 AA017656 gb:ze39h01.r1 Soares retina N2b4HR Homo 0.3125
446404 AA019961 Hs.26216 LOC50627 0.3130
446616 R65964 Hs.241569 ESTs, Weakly similar to ALU8_HUMAN ALU S 0.3132
409404 BE220053 Hs.129056 ESTs 0.3135
417318 AW953937 Hs.12891 ESTs 0.3139
443980 AI459140 Hs.299087 ESTs 0.3140
459138 AI903291 gb:RC-BT029-080199-047 BT029 Homo sapien 0.3142
414807 AI738616 Hs.77348 hydroxyproεtaglandin dehydrogenase 15-{N 0.3143
434704 AW135276 Hε.192311 ESTs 0.3143
414214 D4g958 Hs.75819 glycoprotein M6A 0.3145
446378 AI905699 Hs.239760 citrate synthase 0.3145
450233 AI939966 gb:MRO-CT0015-16070g-002-b06 CT0015 Homo 0.3146
428193 NM 004235 Hs.7934 KruppeHike fxtor 4 (g ut) 0.3148
426515 BE394222 Hs.231444 Homo sapiens, Similar to hypothetical pr 0.3150
426597 AA382250 Hs.145601 ESTs 0.3153
459729 AL037285 Hs.280848 EST, Weakly similar to ALU4_HUMAN ALU SU 0.3157
405071 0.3160
407457 AJ242724 gb:Homo sapfens mRNA for partial putativ 0.3162
409922 AW505582 Hs.130732 KIAA1575 protein 0.3172
438219 AI916151 Hs.257184 ESTs 0.3173
412944 AA384110 Hs.197143 ESTs 0.3175
431103 M57399 Hs.44 pleiotrophiπ (hepariπ binding growth fx 0.3178
426662 AA878474 Hs.122710 ESTs 0.3178
444391 AL137597 Hs.11114 hypothetical protein dJ1181N3.1 0.3179
432168 AK000563 Hs.272805 hypothetical protein FU20556 0.3181
411084 T18987 Hs.125472 ESTs, Moderately similarto KIAA0877 pro 0.3183
425367 BE271188 Hs.155975 protein tyrosine phosphatase, rxeptor t 0.3185
448812 H30775 Hs.22140 BM88 antigen 0.3188
411288 AW835511 gb:QVO-LT0015-180200-127-d02 LT0015 Homo 0.3189
422884 AW860975 Hs.13256 ESTs 0.3190
405535 0.3195
458663 AV658444 Hs.280776 tankyrase, TRF1-interacting aπkyrin-rela 0.3195
455353 W26786 gb:15d7 Human retina cDNA randomly prime 0.3195
414540 BE379050 Hs.306969 Homo sapiens, clone MGC: 10782, mRNA, com 0.3195
428568 AC004755 Hs.184822 Homo sapienε chromosome 19, fosmid 37502 0.3195
428106 BE620016 Hs.182470 PTD010 protein 0.3198
411856 H6789g Hs.4190 Homo sapfens cDNA: FU23269 fis, clone C 0.3202
445682 AW3783g7 gb:RC3-HT0220-031299-012-g06 HT0220 Homo 0.3205
437568 AI954795 Hs.156135 ESTs 0.3205
448943 AI608810 Hε.193288 ESTs 0.3205
431999 AL133573 Hε.272312 Homo sapiens mRNA; cDNA DKFZp434J2235 (f 0.3207
419279 AA235900 Hε.87500 ESTs 0.3208
405913 0.3209
425383 D83407 Hs.156007 Down syndrome critical region gene 1-lik 0.3212
424729 AF063012 Hs.152531 heart and neural crest derivatives expre 0.3212
440020 AI480204 Hε.177131 ESTs 0.3213
429082 AL135682 Hs.22452 Homo sapiens mRNA for KIAA1737 protein, 0.3215
433663 AF083131 Hs.229535 CATX-15 protein 0.3215
400641 0.3216
406140 0.3216
415280 R56473 Hε.268715 ESTs 0.3217
447635 AI669669 Hs.195362 ESTs 0.3217
401887 0.3217
400767 0.3221
457713 H47495 Hs.13810 hypothetical protein MGC15504 0.3221
448758 AB018311 Hs.21917 KIAA0768 protein 0.3222
444750 AW242684 Hε.243623 ESTs 0.3223
411466 AW847669 gb:IL3-CT0213-280100-056-G10 CT0213 Homo 0.3226
432749 NM 01443Ϊ 1 Hs.278909 interleukin 1, eta 0.3231
408112 AW451982 Hs.248613 ESTs 0.3231
433234 AB040928 Hs.65366 KIAA1495 protein 0.3231
422831 R02504 Hs.332943 ESTs 0.3234
403215 0.3236
451868 R85962 Hε.221926 ESTs, Weakly similarto I38022 hypotheti 0.3236
446901 AI347274 gb:tc05d02.x1 NCI CGAP Co16 Homo sapiens 0.3242
430553 AW392821 gb:CM4-ST0275-02129g-053-hOO ST0275 Homo 0.3254
445848 AA774824 Hs.13377 Homo sapienε clone 23640 and 23755 unkno 0.3257
441143 AI027604 Hs.159650 ESTs 0.3257
405138 0.3262
412888 M86151 gb:EST0267g Hippocampus, Stratagene (cat 0.3262
409662 AW452320 Hs.279726 ESTs 0.3262
425438 T62216 Hε.270840 ESTs 0.3263
416426 AA180256 Hs.210473 Homo sapiens cDNA FU14872 fis, clone PL 0.3263
423512 AW844694 Hs.306752 Homo sapiens cDNA FU21391 fis, clone C 0.3264
436777 AA731199 Hs.293130 ESTs 0.3267
431651 BE250915 Hs.266914 hypothetical protein FU10355 0.3267
454117 BE410100 Hs.40368 adaptor-related protein complex 1, sigma 0.3268
426048 AI768853 Hs.134478 ESTε 0.3269
451096 BE383234 Hs.25925 Homo sapiens, clone MGC:15303, mRNA, com 0.3270
426942 AA393551 Hs.97450 ESTs 0.3271 454947 AW846580 gb QV0-CT0180-011099-025- 07 CT0180 Homo 03275
413814 BE169692 gb PM1 HT0527-200200-006-a05 HT0527 Homo 03275
422818 AA404290 Hs 97848 ESTs 03277
423634 AW95g908 Hs 1690 hepaπn binding growth fxtor binding pr 03278
414002 NM 006732 Hs 75678 FBJ muππe osteosarcoma viral oncogene h 03278
452164 AI863171 gb tz44b02 x1 NCI_CGAP_Brn52 Homo sapieπ 03279
458477 NM 000314 Hs 10712 phoεphalase and tensin homolog (mutated 03279
433197 AB040889 Hs 281022 KIAA1456 protein 03280
405701 03282 0 437782 AI370876 Hs 79090 exportiπ 1 (CRM1, yeaεt homolog) 03284
459001 AI761313 Hs 204605 ESTs 03286
422783 AA598g56 Hε 120439 ethanolamine kinase 03289
417036 AF039918 Hs 80975 xtonucleoside tπphosphate diphosphohyd 03290
456041 BE270795 Hs 268864 ESTs 03295
15 423310 AA325225 Hs 124023 HomosapιenscDNA FU14218fis clone NT 03206
427530 AA405093 Hs 126510 ESTε 03206
420172 AA601122 Hs 95655 secreted and transmembrane 1 03297
445610 AI831648 Hs 143993 ESTs 03297
411328 AW837063 gb QV1 LT0037-150200-069-g08 LT0037 Homo 03300 0
Table 8B
Pkey Unique Eos probeset identifier number 5 CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT number Accession
30 409921 1159516 1 AW600239 AW600255 AW505332
410626 1212621.-1 BE407727
410845 122388L1 AW807182 AW807328 AW807063 AW807183 AW807192 AW807033 AW807061 AW807286 AW807097 AW807270 AW807372 AW807280 AW807283
410950 1227728.1 AW811633AW811652AW811898
„ _ 411288 1237709J AW835511 AW835517AW835513
35 411319 1238595J BE537094 AW836542
411328 1238987J AW837063AWg35882AW935957
411466 1246771 1 AW847669 AW847667 BE145799
411514 1248638 AW850178AW850233AW850445AW850446
411620 1252014 1 AW854536AW854417AW854495AW854355
40 411880 1263110 1 AW872477 BE088101 T059gθ
412474 129869J AI791451 AI791288 BE019234 BE296601 AA111939
412506 1301336 1 AW957150H09937T75143
412682 1321572 1 AW983772AW983730AW983769AW983836AW983835AW883837
412888 1334784 M86151 BE061884 BE061883 BE061898 BE061882 BE061887 BE061891 BE061890 BE061896 BE061893 BE061895 BE061894 BE061885 BE007474
45 BE007481 BE007553
413056 1347545.1 BE063031 BE063002 BE063008 BE063024 BE063040 BE063006 BE063072
413537 1375441 1 BE146866 BE146865 BE146867
413541 1375499 1 BE147036 BE146951 BE146958 BE146966 BE146976 BE146955
_ . 413814 1391574.1 BE169692 BE169421
50 414026 1411109 1 BE241713 BE241912
414193 1424706 -2 BE260069
414349 1437515.-1 BE512968
414484 1452830 -1 BE314385
_ , 414539 1460320 1 BE379046 BE395459
55 415154 1525577.1 D63175 D78984D63269
415160 1525766 1 T82802 D78670 R08505
416035 1567254 1 H42314H43080 H45217 H15384
417945 1711126 1 R29072 R29717 R29699 R29709 R29751 R2g609 R29060 R29718 R29057 R29591 R29683 R28575 R28913 R28910 rn 419850 188485.1 F06844 F06845 Z45488 AW748501 AW748591 AW752021 AW748545 AW853362 AW853363 AW853427 AA251253
60 422909 222858.1 AA533356 AW468427 R67736 AA779031 AA614088 AI823404AA318991 AA720986
422954 223239.1 AW998605AW993131 BE51470gAA319445
423621 230314 1 BE002904 H64880 AA328679
424648 241947.1 AA344576AA732430AA344601
426132 261431 1 AA370501 AW962784AA370727
65 426487 268121.1 AA379913AA379g81 AW963523
430553 319868.1 AW392821 AW392809AW843258AW843049 AW603156 BE165656AW821728
431822 338082 1 AA516049AW004922
434098 380006.1 AA625499 AA625269 AA625184
437483 43756 1 AL390174 AW898817
70 440507 485677.1 H06994BE147898
441042 50823.1 AA077736AA078505 BE562497Z17858
441083 50904.1 BE562611 AA436054
445682 647580 1 AW378397AW378390AW378358AI247057
446294 670076.1 AI284935AW40g822BE408182
75 446901 697809.1 AI347274 AW844024
447787 73719.1 BE620108 BE312062AW896316BE262546
451385 86787J AA017656AA017374AA019761
452164 902091 1 AI863171 BE047919
454186 1049791.1 BE141030 BE141474 BE141467 BE141753 BE141024 BE141761 AW177583 AW177579 AW177582 AW177585 AW177587 AW807582 AW177581
80 BE141477 BE141520 BE141456 BE141492 BE141028 BE141775 BE141489 BE141751 AW1775g9 BE141750 AW177597 BE141512 BE141460 BE141749AW177598 454790 1234752.1 AW820852AW820773AW821088
454047 1245953_1 AW846590 AW846615 AW846584 AW846592 AW846621 AW846610
455353 1284289.1 W26786AW998612AW902272
457115 286601 1 AA420712AA469165 AA420737
450138 918860J AI903291 AI903455 AI903367 AI903403 AI903447 AI903405 AI903364 AI903229 AI903240 AI903346
459233 944881 1 AI939966 A1939988 AI939951 A1939981 A1939976 A1939959
Table 8C
Pkey: Unique number corresponding to an Eos probeset
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled The DNA sequence of human chromosome 22." Dunham 1. et al., Nature (1999) 402:489-495. Strand: Indicates DNA strand from which exons were predicted.
N poεition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLposition
400514 9796594 Minus 78844-79025,80850-80891,89754-89941,93750-93891
400641 8117693 Pluε 4786-4992
400672 8118724 Minus 148067-148503
400767 8131627 Minus 80531-80629,82169-82278
400865 1945037 Minus 44482-45526
401024 8117489 Plus 60551-60802
401042 8117611 Plus 151364-151606
401371 9650602 Plus 80901-81283
401381 8570226 Minus 118629-119146,119392-119657
401465 6682292 Plus 25676-25800
401521 7705251 Plus 9127-9234
401753 9838183 Minus 155287-155529,159719-159997
401776 9966323 Plus 115535-115743,117746-117839,120290-120455
401887 7229981 Plus 93973-94120
401974 3126777 Plus 85330-85683
402076 8117410 Plus 128316-128627
402182 8575917 Minus 98298-98439
402425 9796347 Minus 50224-50395
402610 9926549 Minus 22955-23124
402695 8569871 Minus 159927-160055
403047 3540153 Minus 59793-59968
403215 7630945 Minus 177270-177971
403418 6862692 Minus 176202-176395
403548 8081591 Minus 38760-39352
403957 8076835 Minus 81649-81754
404070 2996642 Pluε 7210-7414,10043-10195
404246 7406725 Plus 82477-82628,82721-82817,82910-83071,83149-83387
404414 7382165 Plus 143127-143398
404605 9212566 Plus 125032-125291
404638 9796751 Minus 99433-99528,100035-100161
404696 9800109 Minus 60037-60144,62675-63081
404767 7882827 Minus 23244-23759
404769 8099713 Minus 175801-176823
404927 7342002 Plus 68690-69563
404958 7407941 Minus 2731-4531
405071 7708797 Minus 11115-11552
405073 7769921 Plus 31419-31774
405138 8576241 Plus 90303-90516
405277 3980473 Plus 23471-23572
405282 3810573 Minus 10482-10689
405334 3135285 Plus 139386-138856
405364 2281075 Minus 48325-48491,49136-4g252
405385 6552772 Plus 48332-48454
405535 9795658 Plus 63384-63545
405610 5757553 Minus 71907-72080
405654 4895155 Minus 53624-53759
405691 4508112 Plus 171350-171739
405701 4263751 Plus 93243-93364
405880 6758747 Minus 55673-56287
405913 7712139 Minus 7484-7678
406140 9168231 Minus 49887-50219
406592 4567182 Plus 352560-352963
Table 9A lists about 1 ,234 genes up-regulated in coton cancer compared to normal adult tisεues and to non-malignant colon tissues that are likely to encode proteins amenable to modulation by small motecules, peptides, or antibodies. These were selxted from the starting collxtion of 59680 probesets on the Affymetrix/Eos-Hu03 GeneChip® array as follows: the ratio of "average" colon to "average" normal adult tisεues was greater than or equal to 2.5, the "average" colon level was set to the 90th percentile value amongst colon primary cancer spximens and colon liver derived metatases, the "average" normal adult tissue level was set to the 70th percentile value amongst non-malignant tissues, the "average" colon value was greater than or equal to 50 units, and the predicted protein contained a structural domain that is indicative of have an oncogenic function or of transducing an intracellular signal, or of being modulatable by small motecules, peptides, or antibodies (e.g. pkinase, death-domain, 7tm, phosphatase, or ion.transporter). In order to remove gene-spxific bxkground levels of non specific hybndization, the 15th percentile value amongst the over non malignant tissues was subtrxted from both the numerator and the denominator before the ratio waε evaluated
TABLE 9A 1,234 genes up regulated in colon cancer compared to normal adult tissues and to non malignant colon tissues
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xcession number UnigenelD Unigene number Unigene Title Unigene gene title
R1 90* percentile of tumor samples divided by the 701" percentile of normal body tissue samples, where the 1 δ"1 percentile of normal body tissues was subtrxted from the numerator and denominator
Pkey ExAccn UnigenelD Unigene Title R1
436749 AA584890 Hs5302 NM.006149 Homo sapienε Ixtiπ, galxtosi 2934
406690 M29540 Hs 220529 (tocuslιnk)NM_004363 Homo sapiens carcin 2556
406667 M12523 2028
414386 X00442 Hs75990 NM.005143 Homo sapiens haptoglobin (HP), 1884
428934 AF039401 Hs 194659 NM.001285 Homo sapiens chloπde channel 1738
416768 AA363733 Hs 1032 NM.006507 Homo sapiens regenerating isle 1699
446787 U67167 Hs315 NM 002457 Homo sapiens mucin 2 teεtin 1661
431912 AI660552 Hs 356183 Hs 356183 ESTs, Weakly similar to S3B4.H 1642
437935 AW039591 Hs 5940 NM.033049 Homo sapiens mucin 13, epithet 1592
407242 M18728 (tocuslιnk)NM_002483 Homo sapiens carcin 1584
423541 AA296922 Hs 129778 NM.014471 Homo sapiens senne protease i 1559
441031 AI110684 Hs7645 NM.005141 Homo εapienε fibππogen, B bet 1502
406685 M18728 (tocuεlιπk)NM_002483 Homo sapiens carcin 1454
422578 AF239666 Hs 1545 NM.001804 Homo sapiens caudal type hom∞ 1368
432542 AW083920 Hs 16098 NM.020384 Homo sapienε claudin 2 (CLDN2) 1323
421341 AJ243212 Hs 374281 NM.007329 Homo εapieπs deleted in malign 1321
453863 X02544 Hs572 Hs 572 orosomucoid 1 1306
421582 AI910275 Hs 350470 NM.003225 Homo εapiens trefoil fxtor 1 1235
436217 T53925 Hs107 NM.004467 Homo sapiens fibπnogen like 1 12 11
422260 AA315993 Hs 105484 NM.032044 Homo sapiens regenerating gene 11 99
418888 AU076801 Hs 89436 NM.004063 Homo sapiens cadhenn 17, LI c 11 87
407243 AA058357 Hs74466 (lxuslmk)NM_0068go Homo sapiens carcin 11 81
424212 NM.005814 Hs 143131 NM.005814 Homo sapiens glycoprotem A33 11 27
414463 T69078 Hs76177 NM.001633 Homo sapiens alpha-1 microglob 11 18
407007 U22961 Hs 184411 NM.000477 Homo sapiens albumin (ALB), R 1082
413719 BE43g580 Hs75498 NM.004581 Homo sapiens small inducible c 1073
450685 L15533 Hs423 NM.138938 Homo sapiens pancreatitis asso 1057
418007 M13509 Hs 83169 NM.002421 Homo εapiens matrix metallopro 1039
423673 BE003054 Hs 1695 NM.002426 Homo sapiens matrix metallopro 10 10
423371 AU076819 Hs 1650 NM.000111 Homo εapiens solute earner fa 991
421964 X73079 Hs 288579 NM.002644 Homo sapiens polymeπc immunog 968
447400 AK000322 Hs 18457 NM.017763 Homo sapiens hypothetical prot 944
421100 AW351830 Hs 124660 Hs 124660 ESTε, Moderately similarto 21 938
406741 AA058357 Hs 74466 (tocuslιnk)NM_006890 Homo sapiens carcin 934
427583 M82962 Hs 179704 NM.005588 Homo sapiens mepπn A, alpha ( 9 18
422281 M36803 Hs 346935 NM.000613 Homo sapiens hemopexin (HPX), 906
406687 M31126 Hs352054 Hs 352054 pregnancy spxific beta-1-glyc 902
409153 W03754 Hs 50813 NM.017625 Homo sapiens intelxtin (ITLN) 889
424687 J05070 Hs 151738 NM.004994 Homo sapiens matnx metallopro 853
422664 AA315933 Hs 120879 Hs 120879 Homo sapiens, clone MGC 32871 823
452304 AA025386 Hs61311 Hs 61311 ESTs, Weakly similar to S10590 810
430569 AF241254 Hs 178098 NM.021804 Homo sapiens aπgiotensm I con 805
413881 L00190 Hs 75599 (tocuslιnk)NM_000488 Homo sapiens seπne 796
406399 73
422424 AI186431 Hs 296638 Hs 296638 prostate differentiation facto 771
428470 AC002301 Hs 184507 Hs 184507 Homo sapiens, similarto Homol 743
417931 95642 Hs 82961 Hs 82961 Homo sapiens, clone MGC 22588 1 740
435538 AB011540 Hs4930 Hs 4930 low density lipoprotein receptor 729
430272 X04898 Hε 237658 Hs 237658 apolipoprotein A II 725
451917 AW391351 Hs 50820 Hs 50820 hypothetical cardiac/skeletal m 721
421907 BE018556 Hs 109358 Hs 108358 ATPase, Clasε V, type 10B 7 19
452316 AA298484 Hs61265 NM.138805 Homo sapiens family with seque 7 18
452594 AU076405 Hs 29981 Hs 29981 solute earner family 26 (sulfa 703
424326 NMJ14479 Hs 145296 NM.014479 Homo sapiens ADAM like, dxysi 700
443426 AF098158 Hε9329 (tocuslιnk)NM_012112 Homo sapiens chromo 692
452194 AI694413 Hs373599 Hs 373599 EST 683
411975 AI916058 Hs 144583 Hs 144583 Homo sapiens, clone IMAGE 3462 676
408243 Y00787 Hs624 NM.000584 Homo sapiens interleukin 8 (IL 659
422310 AA316622 Hs 98370 (locuslmk)NM_030622 Homo εapienε cytoch 655
431330 X69532 Hs2777 NM.002215 Homo εapiens inter-alpha (glob 653
420344 BE463721 Hs 97101 NM.014373 Homo sapienε putative G protei 649
422330 D30783 Hs 115263 NM.001432 Homo sapiens epiregulin (EREG) 633
412104 AW205197 Hs 240951 (tocuslιnk)NM_033120 Homo sapiens naked 631
451035 AU076785 Hs430 NM.002670 Homo sapienε plastin 1 (I isof 630
428753 AW03g252 Hs 192927 NM.017726 Homo sapienε protein phosphata 629
430677 Z26317 Hs 359784 NM.001943 Homo sapiens desmoglein 2 (DSG 628
422487 AJ010901 Hs 198267 NM.018406 Homo sapiens mucin 4, trxheob 627
444381 BE387335 Hs 283713 NM.138455 Homo sapiens collagen triple h 626
409632 W74001 Hs 55279 NM.002639 Homo sapiens seπne (or cystei 623 417481 , AW376842 Hs 1085 NM.004963 Homo sapiens guanylate cyclase 623
413936 AF113676 Hs 297681 NM.000295 Homo sapiens seπne (or cystei 623
422627 BE336857 Hs 118787 Hs 118787 transforming growth factor, be 6 19
411825 AK000334 Hs 352415 NM.017767 Homo sapiens solute earner fa 6 17
446921 AB012113 Hs 16530 NM.002988 Homo sapiens small inducible c 6 17
415214 AI445236 Hs 125124 NM 04442 Homo sapiens EphB2 (EPHB2), tr 6 17
414816 Y13709 Hs 77399 NM.001265 Homo sapiens caudal type homx 616
422106 D84239 Hs 111732 NM_0038gθ Homo sapiens IgG Fc binding pr 6 14
423803 NM.005709 Hs 132945 (locuslιnk)NM_00570g Homo sapiens PDZ-73 613
452281 T93500 Hs 28792 Hs 28782 Homo sapiens cDNA FU11041 fis, 609
447342 AI199268 Hs 19322 Hs 19322 Homo sapiens, Similarto RIKEN 602
443957 AA521049 Hs 353013 Hε 353013 chromoεome 20 open reading fra 595
403220 590
408908 BE296227 Hs 250822 (l∞uslιnk)NM_003158 Homo sapiens senne 588
449722 BE280074 Hs 23960 Hs 23960 cyclin B1 587
425976 C75094 Hs 334514 NM.025257 Homo sapiens chromosome 6 open 579
414617 AI339520 Hs 288817 (locuslιnk)NM_025130 Homo sapiens hypoth 579
408983 NM 000492 Hs 663 NM.000492 Homo sapiens cystic fibrosis t 577
423445 NM 014324 Hs 128749 NM.014324 Homo sapiens alpha-methylxyl 577
421379 Y15221 Hs 103982 NM 005409 Homo εapieπs small inducible c 576
431301 AA502384 Hs 151529 Hs 151529 ESTs 571
418318 U47732 Hs 84072 NM.004616 Homo sapiens transmembrane 4 s 571
415992 C05837 Hs 145807 Hs 145807 hypothetical protein FLJ13593 568
436972 AA284679 Hs 25640 Hs 25640 claudin 3 566
414987 AA524394 Hs 294022 NM.032865 Homo sapienε hypothetical prot 561
431657 AI345227 Hs 105448 Hε 105448 protein kinase, lysine deficie 557
424273 W40460 Hs 144442 NM.003561 Homo sapiens phospholipase A2, 555
413916 N49813 HS 75615 NM.000483 Homo sapiens apolipoprotem C- 554
409757 NM 001898 Hs 123114 NM.001888 Homo sapiens cystatiπ SN (CST1 553
430204 AA618335 Hs 356664 Hs 356664 hypothetical protein FU32334 550
426227 U67058 Hs 154299 (lxuslιπk)NM_005242 Homo sapiens coagul 538
420542 NM 000505 Hs 1321 NM.000505 Homo sapiens coagulation fxto 533
414809 AI434699 Hs 77356 Hs 77356 transferπn rxeptor (p90, CD71 532
414639 X67055 Hs 76716 NM.002217 Homo sapiens pre-alpha (globul 532
410418 D31382 Hs 63325 NM.019894 Homo sapiens transmembrane pro 528
414590 NM 000506 Hs 76530 NM.000506 Homo sapiens coagulation facto 528
444151 AW972917 Hs 128749 (tocuslιnk)NM 014324 Homo sapiens alpha- 527
438746 A1885815 Hs 184727 Hε 184727 ESTs, Weakly similar to T45738 526
408704 AA056635 Hs 5366 NM.139053 Homo sapiens epidermal growth 525
414798 AI286323 Hs 97411 Hs 97411 hypothetical protein MGC12335 525
436251 BE515065 Hs 296585 (tocuslιnk)NM_006392 Homo sapiens nuclx 525
414753 AF158255 Hs 77225 NM.006437 Homo sapiens ADP-πbosyltraπsf 523
428970 BE276891 Hs 194691 NM.003979 Homo sapiens retinoic xid iπd 522
443991 NM 002250 Hs 10082 NM.002250 Homo sapiens potassium interme 520
432978 AF126743 Hs 279884 NM.013238 Homo sapienε DNAJ domam-conta 518
425834 NM.001639 Hs 1957 Hε 1957 amyloid P component, εerum 513
432179 X75208 Hs 2913 NM.004443 Homo εapiens EphB3 (EPHB3), R 5 12
408482 NM 000676 i Hs 45743 NM.000676 Homo sapiens adeπosine A2b rx 511
430135 NM 000035 i Hs 234234 NM 000035 Homo sapiens aldolase B, fruct 508
426174 AA547959 Hs 115838 Hs 115838 ESTs 507
403218 507
411142 NM.01425E i Hs 69009 NM.014256 Homo sapiens UDP-GlcNAc betaGa 500
449027 AJ271216 Hs 22880 NM.005700 Homo sapiens dipeptidylpeptida 498
433083 AL042759 Hs 191762 Hs 191762 hypothetical protein MGC20258 496
431779 AWg71178 Hs 268571 (tocuslιnk)NM_001645 Homo sapiens apolip 492
421408 AI688223 Hs 91096 NM.052816 Homo sapiens tripartite motif- 491
430603 AA148164 Hs 247280 Hs 247280 chromosome 20 open reading fra 491
422867 L32137 Hs 1584 Hs 1584 cartilage oligomeπc matnx prot 490
422539 AJ009936 Hs 118138 NM.033013 Homo sapiens nuclear receptor 489
424010 AL080188 Hs 137556 NM.033100 Homo sapiens MT-protocadheπn 486
428953 AA306610 Hs 348183 NM.003823 Homo sapiens tumor nxrosiε fa 486
457001 J03258 Hs 2062 Hε 2062 vitamin D (1,25- dihydroxyvitami 483
425983 AK000226 Hs 165619 NM.031265 Homo sapiens mucin and cadheπ 481
428289 M26301 Hs 2253 Hs 2253 complement component 2 479
418322 AA284166 Hs 84113 NM.005192 Homo sapienε cyclin-dependent 478
409889 AW630041 Hε 56937 NM 021978 Homo εapiens suppresεion of tu 477
447472 AW207347 Hε 211101 Hε 211101 ESTs 474
423164 AK000232 Hε 124835 NM.019062 Homo sapiens hypothetical prot 472
429345 R11141 Hs 199695 Hs 199695 hypothetical protein MAC30 472
430680 AW138724 Hs 168974 Hs 168974 ESTε 469
414998 NM.002543 Hs 77729 NM.002543 Homo sapiens oxidised low dens 469
417165 R80137 Hs 302738 Hs 302738 Homo sapiens cDNA FU21425 fi 467
403221 465
415000 AW025529 i Hs 239812 Hs 239812 serologically defined breast c 465
433437 U20536 Hs 3280 NM.001226 Homo sapiens caspase 6, apopto 464
414052 AW57884S I Hs 283552 Hs 283552 hypothetical protein BC016153 464
406673 M34996 Hs 198253 Hs 198253 major fiistocompatibility compl 464
418203 X54942 Hs 83758 NM.001827 Homo sapiens CDC28 protein km 460
422714 AB018335 Hs 119387 NM.014698 Homo εapienε KIAA0792 gene pro 460
410639 i BE269047 Hs 65234 (lxuslιnk)NM_017895 Homo sapiens DEAD/H 460
411393 l AW79743; ' Hs 69771 NM.001710 Homo sapienε B-fxtor, properd 459
431193 I AW749505 Hs 206770 Hε 296770 KIAA1719 protein 457
42845C I NM 014791 Hs 184339 NM.014791 Homo sapiens maternal embryoni 456 425873 NM 013390 Hε 160417 Hs 160417 transmembrane protein 2 456
422765 AW409701 Hε 1578 NM.001168 Homo sapiens bxuloviral IAP r 455
445109 AF039gi6 Hs 12330 NM.001247 Homo sapiens xtonucleoside tr 455
422535 AA311914 Hs 154578 Hε 154578 Homo εapienε mRNA for FU00256 455
422609 Z46023 Hs 118721 NM.000434 Homo sapienε sialidase 1 (lyso 454
431548 AI834273 Hs 9711 NM.017515 Homo sapiens novel protein (HS 453
429271 AF039850 Hs 198515 NM.005224 Homo sapiens dead πnger like 453
432269 NM.002447 Hs 2942 Hs 2942 mxrophage stimulating 1 rxepto 453
408194 AA601038 Hs 191797 Hs 191797 ESTs 452
439580 AF086401 Hs 293847 Hs 293847 ESTs 450
443464 BE548446 Hs 321579 NM.021095 Homo sapiens solute earner fa 449
420981 L40904 Hs 100724 NM.005037 Homoεapieπs peroxisome prolif 448
432378 AI493046 Hs 146133 Hs 146133 ESTs 448
431958 X63629 Hs 2877 NM.001793 Homo sapiens cadhenn 3, type 447
415099 AI492170 Hs 77917 NM.006002 Homo sapiens ubiquitin carboxy 447
437009 AF127026 Hs 5394 NM.005379 Homo sapiens myosin IA (MY01 A) 447
422511 AU076442 Hs 117938 NM.000494 Homo sapiens collagen, type XV 446
436469 AK001455 Hs 5198 Hs 5198 Down syndrome cπtical region ge 446
445417 AK001058 Hs 12680 Hs 12680 Homo sapiens cDNA FU10196 fis, 444
428024 Z29067 Hs 2236 Hs 2236 NIMA (never in mitosis gene a) r 444
415474 NM 014252 Hs 78457 NM.014252 Homo sapiens solute earner fa 443
441384 AA447849 Hs 288660 Hs 288660 Homo sapiens cDNA FLJ22182 fi 443
428479 Y00272 Hs 334562 NM.001786 Homo sapienε cell diviεion eye 440
407944 R34008 Hs 239727 NM.024422 Homo sapiens desm∞ollin 2 (DS 438
414108 AI267592 Hs 75761 NM.003137 Homo sapiens SFRS protein kma 437
447320 AI675419 Hs 164464 Hs 164464 Homo sapiens, clone MGC 23656 436
410850 AW362867 Hs 302738 Hs 302738 Homo sapienε cDNA FU21425 fi 436
439453 BE264974 Hs 6566 Hs 6566 thyroid hormone rxeptor interx 435
409231 AA446644 Hs 692 NM.002354 Homo sapiens tumor assxiated 433
432575 AA553722 Hs 194346 Hs 194346 Spιr-2 protein 433
427747 AW411425 Hs 180655 (l∞uslιnk)NM_004217 Homo εapienε εeπne 433
439963 AW24752g Hs 6793 Hs 6793 platelet xtivatmg fxtor xety 432
418245 AA088767 Hs 83883 NM.020182 Homo sapiens transmembrane, pr 432
428407 NM 003963 Hs 184194 NM.003963 Homo sapiens transmembrane 4 s 430
424825 AF207069 Hs 153357 NM.001084 Homo sapienε procollagen lyεm 430
429833 NM 012079 Hs 288627 NM.012079 Homo εapiens dixylglycerol 0- 430
411257 AA628967 Hs 115274 Hs 115274 Indian hedgehog homolog (Droso 430
413219 AA878200 Hs 118727 Hs 118727 Homo sapiens cDNA FU33803 fis 429
408847 AW2909g7 Hs 190153 Hs 190153 Homo sapiens cDNA FU33988 fis 429
422163 AF027208 Hs 112360 Hs 112360 prominin like 1 (mouse) 428
425206 NM.002153 Hs 155109 NM.002153 Homo sapiens hydroxysteroid (1 428
441085 AW136551 Hs 181245 Hs 181245 Homo sapienε cDNA FU12532fiε 427
439975 AW328081 Hε 6817 NM.033453 Homo εapienε inosine tnphosph 427
414361 AI086138 Hs 204044 Hs 204044 ESTs 426
417115 AW952792 Hs 334612 NM.003094 Homo sapiens small nuclear πb 426
415927 AL120168 Hs 78919 NM 021083 Homo sapiens Kell blood group 424
409012 AL117435 Hs 49725 Hs 49725 DKFZP434I216 protein 422
420039 NM.004605 Hs 376147 Hs 376147 Homo sapiens cDNA FU39099 fis 420
446051 BEO48061 Hs 37054 Hs 37054 ephππ A3 419
421506 BE302796 Hs 105097 Hs 105097 thymidine kinase 1, soluble 418
407811 AW190902 Hs 40098 Hs 40098 cysteine knot superfamily 1 , BM 418
418054 NM.002318 Hs 83354 NM.002318 Homo sapiens lysyl oxidase-lik 418
409142 AL136877 Hs 50758 Hs 50758 SMC4 structural maintenance of 418
419508 AW897938 Hs 90786 NM.003786 Homo sapiens ATP-binding casse 417
426761 AI015709 Hs 172089 Hs 172089 pro-oncosis receptor inducing 417
408113 T82427 Hs 194101 Hε 194101 Homo sapiens cDNA FU20869fi 416
425743 BE396495 Hs 159428 NM.138761 Homo sapiens BCL2-assxιated X 415
453751 R36762 Hs 101282 Hs 101282 Homo sapiens mRNA cDNA DKFZp4 415
435327 BE301871 Hs 4867 Hs 4867 annosyl (alpha-1,3-)-glycoprote 414
403219 414
407103 AA424881 Hs 256301 Hs 256301 hypothetical protein MGC13170 414
411126 NM.001202 ! Hs 68879 (tocuslιnk)NM_001202 Homo εapiens bone m 414
424837 BE276113 Hs 333034 NM.003401 Homo sapiens ARD1 homolog, N a 413
409956 AW103364 Hs727 NM_002ig2 Homo sapienε inhibin, beta A ( 412
439659 AW870780 Hs 59483 Hs 59483 leucme-πch repeat-containing 412
425397 J04088 Hs 156346 NM.001067 Homo sapiens topoisomerase (DN 412
413753 U17760 Hs 75517 NMJ00228 Homo sapiens laminin, beta 3 ( 411
428698 AA852773 Hs 334838 Hs 334838 KIAA1866 protein 410
427557 NM.00265Ϊ 1 Hs 179657 NM.002659 Homo sapiens plas inogen xtiv 409
441623 AA315805 Hs 348710 Hs 348710 Homo sapiens, clone IMAGE 4242 407
417866 AW067803 Hs 82772 Hs 82772 collagen, type XI, alpha 1 407
442013 AA506476 Hs 375009 Hs 375009 Homo sapiens mRNA, cDNA DKFZp6 406
425247 NM_005g40 Hs 155324 Hs 155324 matnx metaltoproteinase 11 (s 406
428385 AF112213 Hs 184062 Hs 184062 chromosome 20 open reading fra 405
412612 NM 000047 Hs 74131 NM.000047 Homo sapiens arylsulfatase E ( 404
425280 U31519 Hs 1872 NM.002591 Homo sapiens phosphoenolpyruva 403
411263 BE297802 Hs 69360 NM.006845 Homo sapiens kmesin like 6 (m 403
452017 AF109302 Hs 27495 Hs 27495 prostate cancer associated prot 403
452721 AJ26g529 Hs 301871 Hs 301871 solute earner family 37 (glyc 402
450737 AW007152 Hs 63325 Hs 63325 transmembrane protease, senne 401
456906 AF117646 Hs 156637 NM.012116 Homo sapiens Cas-Br-M (muπne) 401
412974 R18978 Hs 75105 NM.006579 Homo sapiens emopamil binding 401
426108 AA622037 Hs 166468 NM.004708 Homo sapiens programmed cell d 401 416065 BE267931 Hs.78996 NM_002592:Homo sapiens proliferating eel 3.99
403739 3.99
417576 AA339449 Hs.82285 NM_000819:Homo sapiens phosphoribosylgly 3.98
405484 3.98
409162 H25530 Hs.50868 Hs.50868:solute carrier family 22 (organ 3.98
430514 AA318501 Hs.241587 NM_021246:Homo εapieπε lymph∞yte antige 3.97
414695 BE439915 Hε.76913 Hε.76913:proteasome (prosome, mxropain) 3.97
411165 NM 000169 Hs.69089 NM_000169:Homo εapiens galxtosidase, al 3.97
421975 AW961017 Hs.6459 (locuεlink)NM_024531:Homo sapiens hypoth 3.96
431836 AF178532 Hs.271411 NM_138992:Homo sapiens beta-site APP-cle 3.96
412133 U83460 Hs.104557 NM_001859:Homo sapiens solute carrier fa 3.96
412870 N22788 Hs.82407 NM_022059:Homo sapiens chemokine (C-X-C 3.95
413278 BE563085 Hs.833 Hs.833:interferon-sfimulated protein, 15 3.95
400130 Hs.155560 NM_001746:Homo sapiens calnexin (CANX), 3.93
430696 AA531276 Hs.59509 Hs.59500:ESTε, Weakly similar to similar 3.93
443802 AW504924 Hs.g805 Hs.9805:exportin 5 3.93
407777 AA161071 Hs.71465 Hs.71465:squalene epoxidase 3.92
456629 AW891965 Hs.367g42 Hs.367942:Homo sapienε, clone IMAGE:4701 3.92
421943 BE616520 Hε.343912 NM_033504:Homo sapiens CAC-1 (CAC-1), mR 3.91
422293 X94453 Hs.114366 Hs.114366:pyrroline-5-carboxy!ate synthe 3.90
419488 AA316241 Hs.90691 NM_006993:Homo sapiens nucleophosmiπ/nuc 3.89
425123 AW205274 Hs.154695 NM_000303:Homo sapiens phosphomannomutas 3.89
447343 AA256641 Hs.236894 Hs.236894:ESTs, Highly similar to S02392 3.88
413254 U40272 Hs.75253 NM.004135:Homo sapiens isocitrate dehydr 3.88
413950 AA249096 Hε.32793 Hs.32793:Homo sapienε cDNA FU31108 fiε, 3.88
409453 AI885516 Hs.95612 Hε.05612:ESTs 3.87
452888 AWg55454 Hs.30942 NM_004093:Homo sapfens ephrin-B2 (EFNB2) 3.86
421910 NM 014586 Hs.109437 NM_014586:Homo sapiens hormonally upregu 3.86
434263 N34895 Hε.79187 Hs.79187:coxsackie virus and adenoviras 3.85
444700 NM.003645 Hs.11729 NM_003645:Homo sapiens fatty-xid-Coenzy 3.85
433662 W07162 Hs.150826 NM_020387:Homo sapiens RAB25, member RAS 3.84
418526 BE019020 Hs.85838 NM_004207:Homo sapfens solute earner fa 3.84
425998 AU076629 Hs.165950 NM.002011 :Homo sapiens fibroblast growth 3.84
422616 BE300330 Hs.118725 NM_012248:Homo sapiens selenophosphate s 3.83
408056 AA312329 Hs.42331 Hs.42331:ephrin-A4 3.83
407233 X16354 Hs.50964 ι(lxusliπk)NM_001712:Homo sapiens carcin 3.83
426514 BE616633 Hs.170195 Hs.170195:bone moφhogenetic protein 7 ( 3.82
451541 BE279383 Hs.26557 NM_007183:Homo sapienε plakophilin 3 (PK 3.82
424441 X14850 Hs.147097 Hs.147097:H2A histone family, member X 3.81
426378 U80082 Hs.169600 Hs.169600:KIAA0826 protein 3.81
409636 AA305729 Hs.18272 (tocuslink)NM_030674:Homo sapiens solute 3.81
407786 AA687538 Hs.38972 NM_005727:Homo sapiens tetraspan 1 (TSPA 3.80
431045 AW000827 Hs.11962 NM_030766:Homo sapiens apoptosis regulat 3.79
414561 AI064813 Hs.195155 Hs.195155:solute earner family 38, memb 3.79
405556 3.79
453082 H18835 Hs.31608 (tocuslink)NM_017636:Homo sapiens transi 3.79
400529 3.79
412869 AA290712 Hε.82407 Hs.82407:chemokine (C-X-C motif) ligand 3.78
427239 BE270447 Hε.356512 Hs.356512:ESTs, Weakly similar to UBCA.A 3.78
429638 AI916662 Hs.211577 (l∞uslink)NM_004986:Homo sapiens kinxt 3.77
445462 AA378776 Hs.288649 (tocuslink)NM_024051:Homo sapiens hypoth 3.77
415003 M11437 Hs.77741 Hs.77741 :kininogen 3.77
443639 BE269042 Hs.9661 Hs.9661:proteasome (prosome, mxropain) 3.76
400290 H18836 Hε.31608 (lxuslink)NM_017636:Homo εapienε transi 3.76
431350 AI192528 Hε.164537 Hs.164537:ESTs 3.76
430154 AW583058 Hs.234726 NM_001085:Homo sapfens serine (or cystei 3.75
435099 AC004770 Hs.4756 NM 004111:Homo εapieπs flap structure-εp 3.75
418216 AA662240 Hε.283099 Hε.283089:AF15q14 protein 3.74
414907 X90725 Hs.77597 NM_000998:Homo sapiens ribosomal protein 3.74
413063 AL035737 Hs.75184 Hs.75184:chitinase 3-like 1 (cartilage g 3.73
420665 AW469240 Hε.371581 Hs.371581:ESTε 3.73
452299 AW206330 Hε.355663 Hε.355663:ESTs 3.72
444664 N26362 Hs.11615 NM_016086:Homo sapienε map kinaεe phoεph 3.72
450334 AF035959 Hs.24879 Hε.24879:phosphatidic xid phosphatase t 3.72
444006 BE395085 Hs.334762 (locuslink)NM_032832:Homo sapienε hypoth 3.72
449437 AI702038 Hs.100057 Hs.100057:serine/threonine kinase 35 3.71
412939 AW411491 Hs.75069 Hs.75069:εerine hydroxymethyltransferase 3.71
427490 Z95152 Hε.178695 NM_002754:Homo sapiens mitogen-xtivated 3.71
427333 AF067797 Hs.176658 NM_001169:Homo sapiens aquaporin 8 (AQP8 3.70
434203 BE262677 Hs.283558 NM.018509;Homo sapiens hypothetical prot 3.70
414806 D14694 Hs.77329 (lxuslink)NM_014754:Homo sapiens phosph 3.70
456362 AW973003 Hs.179909 (tocuslink)NM_024831:Homo sapienε nuclea 3.69
409003 BE243834 Hs.50441 NM.015936:Homo sapieπε CGI-04 protein (L 3.69
437016 AU076916 Hs.5398 Hs.5388:guanine monphosphate εynthetase 3.69
430387 AW372884 Hs.240770 Hs.240770:nuclear cap binding protein su 3.69
428023 AL038843 Hs.374530 Hε.374530:Homo εapienε cDNA: FU23602 fi 3.69
432593 AW301003 Hs.51483 Hs.51483:Homo sapiens, Similarto RIKEN 3.68
413813 M96956 Hs.75561 NM_003212:Homo sapiens terat∞arciπoma-d 3.68
428376 AF119665 Hs.184011 Hs.184011:pyrophosphatase (inorganic) 3.67
431890 X17033 Hs.271086 NM_002203:Homo εapiens integrin, alpha 2 3.67
446696 AF279265 Hs.298476 NM.022911 :Homo sapienε εolute earner fa 3.67
419378 R24g22 Hε.90078 H8.90078:nucleotide-sugar transporter si 3.67
448140 AF146761 Hε.20450 NM_020125:Homo sapiens B lymphocyte xti 3.67 452679 Z42387 Hs 83883 (locuslιnk)NM_020182 Homo sapiens transm 366
432636 AA340864 Hs278562 NM.001307 Homo sapiens claudin 7 (CLDN7) 366
433020 AI375726 Hε 227152 NM.016381 Homo sapienε hypothetical prot 366
425003 AF119046 Hs 154149 NM.014481 Homo sapiens APEX nuclease (ap 366
413095 AA4g4359 Hs 30715 Hs 30715 potasεium voltage-gated channel 366
417386 AL037228 Hs301957 NM.018144 Homo sapiens Sec61 alpha form 365
409152 AA176585 Hs 194346 Hs 194346 Spιr-2 protein 364
404826 363
453111 AB014598 Hs 31720 NM 014799 Homo sapiens hephaestin (HEPH) 363
409964 AW368226 Hs67928 Hs 67928 ESTs 363
446342 BE298665 Hs 14846 Hs 14846 Homo εapiens mRNA, cDNA DKFZp56 363
452098 AI858183 BF755030 QVO CT0583-18100O-428-fO7 CT058 362
428072 BE258602 Hε 182366 NM.016292 Homo sapiens heat shxk protei 361
439223 AW238299 Hε250618 NM.025217 Homo sapienε UL16 binding prot 360
408137 AI694131 Hs 29002 Hs 29002 KIAA1706 protein 359
421959 AW751497 Hs 98370 NM.030622 Homo sapiens cytochrome P450, 359
436856 AI469355 Hs 127310 (l∞uslιnk)NM_144624 Homo sapiens kinase 359
449667 AB023227 Hs23860 Hs 23860 KIAA1010 protein 359
406684 X16354 Hs 50964 (tocuslιnk)NM_001712 Homo sapiens carcin 358
424534 D87682 Hs 150275 Hs 150275 KIAA0241 protein 358
426031 AA295251 Hs 166066 (tocuslιnk)NM_006697 Homo sapiens cispla 358
417526 AA568906 Hs82240 Hs 82240 syntaxm 3A 357
443044 N28522 Hs8935 NM.014298 Homo sapiens qumolinate phosp 357
424154 AF026004 Hs 141660 NM.004366 Homo sapiens chloπde channel 357
432886 BE159028 Hs 279704 Hs 279704 chromatin xcessibility comple 356
413880 AI660842 Hs 110915 NM.021258 Homo sapiens interleukin 22 re 355
421357 AK000609 Hs 103808 NM.017896 Homo sapiens chromosome 20 ope 355
436827 H72187 Hs 356668 (lxuslιnk)NM_005274 Homo sapiens guamn 355
416084 L16991 Hs79006 NM.012145 Homo sapiens deoxythymidylate 355
420162 BE378432 Hs95577 NM.052984 Homo sapiens cyclin-dependent 365
413476 U25849 Hs 75393 NM.004300 Homo sapiens xid phosphatase 355
412115 AK001763 Hs 73239 Hs 73239 hypothetical protein FU 10901 355
413588 AA971014 Hs 75432 NM.000884 Homo sapiens IMP (inosine mono 354
431512 BE270734 Hs2795 Hs 2795 Ixtate dehydrogenase A 354
435777 AW419202 Hs 286192 NM.032192 Homo sapiens protein phosphata 354
431211 M86849 Hs 323733 Hs 323733 gap junction protein, beta 2, 354
453258 AW293134 Hs 32597 NM.005977 Homo sapiens nng finger prate 353
414812 X72755 Hs77367 NM.002416 Homo sapiens monokine induced 353
423068 M25629 Hs 123107 NM.002257 Homo sapiens kallikrein 1, ren 353
443180 R15875 Hs 258576 NM.012129 Homo sapiens claudin 12 (CLDN1 353
425047 U34038 Hs 154299 NM.005242 Homo sapiens coagulation fxto 353
449057 AB037784 Hs22941 Hs 22941 KIAA1363 protein 352
444184 T87841 Hs 282990 (locuslιnk)NM_033550 Homo sapiens chromo 352
412641 M16660 Hs74335 Hs 74335 heat shxk 90kD protein 1 , beta 351
413781 J05272 Hs850 (lxuslιnk)NM_000883 Homo sapiens IMP (i 351
409213 U61412 Hs51133 NM.005975 Homo sapiens PTK6 protein tyro 351
447495 AW401864 Hs 18720 NM.004208 Homo sapienε programmed cell d 351
447200 BE543146 Hs 281434 Hs 281434 Homo sapiens cDNA FU31373 fis 351
408683 R58665 Hs 46847 NM.016614 Homo sapiens TRAF and TNF r∞e 351
431842 NM 005764 Hs271473 Hs 271473 epithelial protein up-regulate 351
457284 AF102850 Hs 227933 NM.013338 Homo sapiens Alg5, S cerevisi 351
411678 AI907114 Hs 71465 NM.003129 Homo sapiens squalene epoxidas 351
437704 AA766142 Hs 131810 Hs 131810 Homo sapiens cDNA FU35976 fis 351
419693 AA133749 Hs301350 Hs 301350 FXYD domain-containing ion tra 351
407971 AI469117 Hs 62918 Hs 62918 CDC91 cell division cycle 91-lι 350
424865 AF011333 Hs 153563 NM.002349 Homo sapiens lymphxyte antige 350
432211 BE274530 Hs 273333 Hs 273333 hypothetical protein FU10986 350
436014 AF281134 Hε283741 NM.020158 Homo sapienε exosome component 350
436278 BE396290 Hs 5097 Hs 5097 synaptogyπn 2 350
440334 BE276112 Hs7165 NM.003904 Homo sapiens zinc finger prate 350
428788 AF082283 Hs 193516 NM.O03921 Homo sapiens B-cell CLUIympho 350
424909 S78187 Hs153752 (lxuslιnk)NM_004358 Homo sapiens cell d 350
407722 BE252241 Hs 38041 NM.003681 Homo sapiens pyπdoxal (pyπdo 349
417129 AI381800 Hs 300684 Hs 300684 calcitonin gene-related pepbd 349
409463 AI458165 Hs 17296 NM.023830 Homo sapiens hypothetical prot 348
407137 T97307 348
454390 AB020713 Hs 56966 (l∞uslιnk)NM_024923 Homo sapiens hypoth 348
438485 W57578 Hs 378718 Hs 378718 Homo sapiens cDNA FU33433 fis 348
423750 AF165883 Hs 298229 NM.012394 Homo sapiens prefoldin 2 (PFDN 347
446946 AI878932 Hs317 NM.003286 Homo sapienε topoisomerase (DN 347
413380 AI904232 Hs 75323 Hs 75323 prohibitjn 346
430237 AI272144 Hs 236522 Hε 236522 DKFZP434P106 protein 346
436127 W94824 Hs 11565 NM.080748 Homo sapiens chromosome 20 ope 345
407770 AW607831 Hs38738 NM.014343 Homo sapiens claudin 15 (CLDN1 345
411950 T28407 Hs 81564 NM.002619 Homo sapiens platelet fxtor 4 344
434845 BE267057 Hs 325321 Hs 325321 WD repeat domain 18 344
420319 AW406289 Hs 965g3 NM.019034 Homo sapiens ras homolog gene 344
425209 AL049761 Hs155140 NM.001895 Homo sapiens casein kinase 2, 344
410174 AA306007 Hs 59461 Hs 59461 DKFZP434C245 protein 343
429023 NM.00031; ! Hs2351 NM.000312 Homo sapiens protein C (inxti 343
426459 AF151812 Hs 169992 NM.015966 Homo sapiens serologically def 343
437967 BE277414 Hs5947 NM.005370 Homo sapiens mel transforming 343
428093 AW594506 Hε 104830 Hs 104830 ESTs 343 414862 BE621310 Hs 923 Hs 923 single-stranded DNA binding prate 343
400750 342
413186 AU077141 Hs 374548 Hs 374548 solute earner family 16 (mono 341
425263 NM.001197 ' Hs 155419 NM.001107 Homo sapiens BCL2-ιnterxtιng 340
453857 AL080235 Hs 35861 Hs 35861 Ras induced εenescence 1 340
428474 AB023182 Hs 184523 Hs 184523 seπne/threoniπe kinase 38 lik 339
410315 AI638871 Hs 378965 Hs 378865 Homo sapiens cDNA FU37658 fis 339
428206 AB020643 Hs 183006 Hs 183006 likely homolog of mouse hepaπ 339
450506 NM.004460 ι Hs 418 (l∞uslιnk)NM_004460 Homo εapiens fibrob 339
413178 N99692 Hs 75227 NM.005002 Homo sapiens NADH dehydrogeπas 338
440676 NM.004987 Hs 112378 (locuslιnk)NM_004987 Homo sapiens UM an 338
400847 337
431685 AW296135 Hs 267659 NM.006113 Homo sapiens vav 3 oncogene (V 337
410199 AW377424 Hs 205126 Hs 205126 Homo sapiens cDNA FU22667 fi 337
432633 AI796390 Hs 210667 Hs 210667 ESTs 336
429344 R94038 Hs 374664 NM.005538 Homo sapiens inhibin, beta C ( 336
424685 W21223 Hs 151734 Hs 151734 nuclear transport factor 2 336
456850 AF111170 Hs 306165 Hs 306165 ESTs Highly εimilar to unknow 335
418313 BE244231 Hs 84038 NM.015937 Homo sapiens CGI-06 protein (L 335
453454 AW052006 Hs 374973 NM.004697 Homo sapiens PRP4 pre mRNA pro 335
400448 335
424142 AI678727 Hs 378970 Hs 378970 Homo sapiens cDNA FLJ35102 fis 335
430720 U85768 Hs 247838 NM.002991 Homo sapiens small inducible c 335
416412 NM.014742 Hs 79305 Hs 79305 KIAA0255 gene product 335
428824 AA206363 Hs 121520 Hs 121520 Homo sapiens cDNA FU35792fis 335
412948 BE243313 Hs 334851 Hs 334851 UM and SH3 protein 1 334
451129 BE072881 BE072881 RC2 BT0548-200300-012 e00 BT054 334
425322 U63630 Hs 155637 NM.006904 Homo sapiens pratem kinase D 334
446291 BE397753 Hs 14623 Hs 14623 interferon gamma-mducible pro 334
431731 BE266322 Hs 211374 (tocuslιnk)NM_145051 Homo sapienε hypoth 334
423198 M81933 Hs 1634 Hs 1634 cell division cycle 25A 334
448093 AW977382 Hs 15898 Hs 15898 24-dιenoyl CoA reductase 2 pe 334
414045 NM 002951 Hs 75722 NM.002951 Homo sapiens πbophoπn II (RP 334
421190 U95031 Hs 102482 Hs 102482 mucin 5, subtype B, tracheobro 334
419607 R52557 Hs 91579 NM.033416 Homo sapienε similar to HYPOTH 333
435975 AL118990 Hs 373554 (locuslιnk)NM_130786 Homo εapiens alpha- 333
418416 U11700 Hs 84999 NM.000053 Homo εapienε ATPase, Cu++ tran 333
433570 AI580053 Hs 109007 Hε 109007 Homo sapiens Similar to LOC16 333
441128 AA570256 Hs 348504 Hs 348504 hypothetical protein BC014072 333
432320 AW411066 Hs 274351 NM.016032 Homo sapiens zinc finger, DHHC 333
444019 BE173977 Hs 10098 NM.019082 Homo sapiens putative nucleola 332
432680 T47364 Hs 278613 (tocuslιnk)NM_005532 Homo sapiens interf 332
410219 T98226 Hs 171952 Hs 171952 ∞cludin 332
410663 AA194952 Hs 36093 Hs 36093 Homo εapienε cDNA FLJ 12885 fis 332
402829 332
445921 AW015211 Hs 153799 Hs 153799 Homo sapiens cDNA FLJ38333 fis 332
414198 AW505308 Hs 75812 NM.004563 Homo sapiens phosphoenolpyruva 332
443425 AI056776 Hs 133397 Hε 133397 ESTs 332
436485 X59135 Hs 156110 Hs 156110 immunoglobulin kappa constant 331
410268 AA316181 Hs 61635 NM.012449 Homo sapiens six transmembrane 330
425159 NM.004341 Hs 154868 NM.004341 Homo sapiens carbamoyl-phospha 330
420614 AL110291 Hs 99364 Hs 99364 abhydrolase domain containing 1 330
421814 L12350 Hs 108623 NM.003247 Homo sapiens thrombospondin 2 330
432215 AU076609 Hs 2934 NM.001033 Homo sapiens πbonucleotide re 330
409402 AF208234 Hs 695 Hs 695 cystatιn B (stefin B) 330
421038 AL080192 Hs 101282 Hs 101282 Homo sapiens mRNA, cDNA DKFZp4 329
424408 AI754813 Hε 146428 Hs 146428 collagen, type V, alpha 1 329
448775 AB025237 Hε 388 NM.002452 Homo sapiens nudix (nucleoside 329
442821 BE391929 Hs 8752 Hs 8752 tranεmembrane protein 4 329
459306 AW578452 AW578452 RC1-CT0252-030100-023-b07 CT025 328
400846 328
422256 M64673 Hs 1499 NM.005526 Homo εapieπs heat sh∞k transc 328
408089 H59799 Hs 42644 Hs 42644 thioredoxin like 2 328
432078 BE314877 Hs 24553 (tocuslιnk)NM_022369 Homo εapiens hypoth 327
435575 AF213457 Hs 44234 NM.018965 Homo sapiens tπggeπng recept 327
456534 X91195 Hs 100623 NM.138689 Homo sapiens protein phosphata 327
447335 BE617695 Hs 286192 NM.032192 Homo sapiens protein phosphata 327
414368 W70171 Hs 75939 NM.012474 Homo sapiens undine moπophosp 327
422599 BE387202 Hs 118638 Hs 118638 non metastatic cells 1, protei 326
437897 AA770561 Hs 146170 Hε 146170 hypothetical protein FU22969 326
431183 NM.O06855 Hs 250696 NM.006855 Homo sapiens KDEL (Lys Asp-Glu 326
457635 AV660976 Hs 3569 Hε 3569 chromosome 20 open reading frame 326
432381 AI732374 Hs 339827 Hs 339827 ESTs, Weakly similar to protea 325
417640 D30857 Hs 82353 NM.006404 Homo sapienε protein C rxepto 325
440086 NM.005402 Hs 6906 NM.005402 Homo εapiens v ral simian leuk 325
401178 325
411125 AA151647 Hs 68877 Hs 68877 cytochrome b-245, alpha polypep 325
453323 AF034102 Hs 32051 NM.001532 Homo sapiens solute earner fa
407236 325
W79485 Hs 173980 Hs 173980 nuclear matnx protein NMP200 325
447250 AI878909 Hs 17883 NM.002707 Homo sapienε protein phosphata 325
452875 BE275760 Hs 30928 NM.006114 Homo sapiens translocase of ou 324
428380 AI640377 Hs 350077 NM.000982 Homo sapiens πbosomal protein
425811 324
AL039104 Hs 159557 NM.002266 Homo sapiens karyopheπn alpha 324 446356 AI816736 Hs.14896 Hs.14896:zinc finger, DHHC domain contai 3.24
419170 BE002798 Hs.287850 NM_002219:Homo sapiens integral membrane 3.24
426858 NM 004182 Hs.172791 NM.004182:Homo sapiens ubiquitously-expr 3.23
418558 AW082266 Hs.86131 Hs.86131:Fas (TNFRSF6)-aεsociated via de 3.23
444706 AK000398 Hs.11747 (lxuslink)NM_017798:Homo sapienε chromo 3.23
444734 NM 001360 Hs.11806 NM_001360:Homo εapienε 7-dehydr∞holeste 3.23
424482 BE268621 Hs.149155 (lxuslink)NM_003374:Homo sapienε voltag 3.23
438203 BE540090 Hs.7345 Hs.7345:MAD1 mitotic arreεt deficient-]! 3.23
409686 AK000002 Hs.55879 (locuslink)NM_033450:Homo sapiens multid 3.23
418681 AA287786 Hs.23449 Hs.23449:iπsulin rxeptor tyrosine kinas 3.23
419705 AW368634 Hs.154331 Hs.154331:ESTs 3.22
420186 NM 015925 Hs.95697 Hs.95697:liver-specific bHLH-Zip transcr 3.22
413835 AI272727 Hs.249163 NM_024306:Homo sapfens fatty xid hydrox 3.22
448153 Y10805 Hs.20521 NM_001536:Homo sapfens HMT1 hnRNP methyl 3.22
425274 BE281191 Hs.155462 Hs.155462:MCM6 minichromosome maintenanc 3.21
435472 AW972330 Hs.283022 NM_018643:Homo sapiens triggering recept 3.21
451932 AA360954 Hs.27268 Hs.27268:Homo εapienε cDNA: FU21933 fis 3.21
420085 AI741909 Hs.44680 Hs.44680:hypothetical protein FU20979 3.21
412006 AW451618 Hs.290216 Hs.290216:ESTs 3.21
424954 NM 000546 Hs.1846 NM_000546:Homo sapiens tumor protein p53 3.21
437741 BE561610 Hs.5809 NM_020470:Homo sapiens putative transmem 3.21
414602 AW630088 Hs.76550 NM_052886:Homo sapiens mal, T-cell diffe 3.20
400263 Hs.75309 NM_001961:Homo sapiens eukaryotic transi 3.20
434457 AF141332 Hs.200333 NM.018690:Homo sapienε apolipoprotein B4 3.20
452203 X57522 Hs.352018 NM_000593:Homo εapieπs transporter 1 , AT 3.20
413431 AW246428 Hs.75355 NM_003348:Homo sapieπε ubiquitin-conjuga 3.19
437379 AL359575 Hs.23765 Hs.23765:membraπe metallo-endopeptidase- 3.19
408716 AI567839 Hs.151714 (lxuslink)NM_033405:Homo sapiens peroxi 3.19
433627 AF078866 Hs.284296 NM_033161:Homo sapiens surfeit 4 (SURF4) 3.19
430393 BE185030 Hs.241305 (lxusliπk)NM_006470:Homo sapiens tripar 3.19
417286 AA122237 Hs.81874 NM_002413:Homo sapiens microsomal glutat 3.18
434224 AA380731 Hs.84 NM_000206:Homo sapieπε interleukin 2 rx 3.18
428028 U52112 Hs.182018 Hs.182018:interieukin-1 receptor-ass∞ia 3.18
445580 AF167572 Hs.12912 NM_006109:Homo sapiens SKB1 homolog (S. 3.18
420531 AI652069 Hs.98614 NM_004587:Homo sapiens ribosome binding 3.18
417389 BE260964 Hs.82045 Hs.82045:midkiπe (neurite growth-pramoti 3.18
412276 BE262621 Hs.73798 Hs.73798:mxrophage migration inhibitory 3.18
452700 AI859390 Hs.288940 NM 021259:Homo sapiens transmembrane pro 3.18
433604 NM.013442 Hs.3439 Hs.3439:stomatin (EPB72)-like 2 3.18
414883 AA926960 Hε.348669 Hs.348669:CDC28 protein kinase 1 3.18
421743 T35958 Hs.107614 Hs.107614:DKFZP564H 171 protein 3.18
447698 AI420156 Hs.326733 NM_052858:Homo sapiens similar to RIKEN 3.17
424089 AL036662 Hs.144949 Hs.144949:ESTs 3.17
414788 X78342 Hs.77313 Hs.77313:cyclin-dependent kinase (CDC2-I 3.17
442315 AA173992 Hs.7956 Hs.7956:ESTε 3.17
449944 AF290512 Hs.58215 (locuslink)NM_033046:Homo sapiens rhotek 3.17
425244 AK002127 Hs.155313 NM_022105:Homo sapiens death assxiated 3.16
428484 AF104032 Hs.184601 (l∞uslink)NM_003486:Homo sapiens solute 3.16
418703 NM 014448 Hs.87435 Hs.87435:Rho guanine exchange factor (GE 3.16
436415 BE265254 Hs.343258 NM_006191:Homo sapiens proliferation-ass 3.15
447151 AI022813 Hs.92679 (tocuslink)NM_145754:Homo sapienε klπesi 3.15
418862 BE550964 Hs.893g9 NM_005176:Homo sapiens ATP synthase, H+ 3.15
410636 AA088177 Hs.172870 Hs.172870:KIAA1013 protein 3.15
423599 AI805664 Hs.31731 (locuslink)NM_012094:Homo sapiens peroxi 3.15
435886 BE265830 Hs.12126 NM.018487:Homo sapiens hepat∞ellularca 3.15
458778 AW451034 Hs.326525 NM_001669:Homo sapienε arylsulfatase D ( 3.14
420190 AI816209 Hs.95867 (lxuslink)NM_024112:Homo sapiens chromo 3.14
428371 AB012193 Hs.183874 NM_003589:Homo sapiens cullin 4A (CUL4A) 3.14
450690 AA296696 Hs.333418 (tocuslink)NM_014164:Homo sapiens FXYD d 3.14
413900 AW409747 Hε.75612 NM_006819:Homo sapiens stress-induced-ph 3.13
406698 X03068 Hs.73931 Hs.73931 major histocompatibility comple 3.13
407797 AK000524 Hs.39850 Hs.39850:uridine kinase-like 1 3.13
447321 AW271217 Hε.281434 Hs.281434:Homo sapiens cDNA FU31373 fis 3.13
426841 AI052358 Hs.131741 Hs.131741:ESTs 3.13
418650 BE386750 Hs.86978 Hε.86978:prolyl endopeptidase 3.12
420676 AI434780 Hs.4248 Hs.4248:Homo sapienε PP3781 mRNA, comple 3.12
438444 AI064707 Hs.301226 Hε.301226:Homo εapienε, clone IMAGE:3456 3.12
439778 AL109729 Hs.99364 Hε.g9364:abhydrolaεe domain containing 1 3.12
412326 R07566 Hs.73817 NM_002983:Homo sapiens small inducible c 3.12
447656 NM.003726 Hs.19126 NM_003726:Homo sapiens src family ass∞i 3.12
428109 AW732918 Hs.182490 Hs.182490:leucine-rich PPR-motif contain 3.11
421779 AI879159 Hs.108219 NM_004626:Homo sapfens winglesε-type MMT 3.11
400262 Hs.75309 NM_001061:Homo sapienε eukaryotic transi 3.11
418803 U50079 Hs.88556 NM_004g64:Homo sapiens histone dexetyla 3.11
449230 BE613348 Hs.356392 Hs.356392:ESTs, Highly similar to S-phas 3.11
421532 AW138207 Hs.146170 NM_022842:Homo sapienε hypothetical prot 3.11
432026 AA524545 Hs.224630 Hε.224630:Homo εapiens cDNA FU33318 fis 3.11
433179 AW362945 Hs.162459 Hs.162459:ESTs 3.11
452264 AU077013 Hs.28757 Hs.28757:transmembrane 9 superfamily mem 3.11
418641 BE243136 Hs.86947 NM_001109:Homo sapiens adisintegrin and 3.10
421612 AF161254 Hs.106196 (tocustink)NM_016579:Homo sapienε 8D6 an 3.10
427349 AA360154 Hε.177415 (locuslink)NM_001997:Homo εapienε Rnkel 3.10
457670 AF119666 Hs.23449 NM_018842:Homo sapiens insulin rxeptor 3.10 438407 AI457122 Hs 129673 Hε 129673 eukaryotic translation imtiat 310
428293 BE250944 Hs 183556 Hs 183556 εolute earner family 1 (neutr 3 10
436823 AW749865 Hs 117077 Hs 117077 zinc finger protein 264 3 10
418181 U37012 Hs 83727 NM.013291 Homo sapiens cleavage and poly 3 10
434826 AF155661 Hs 22265 Hs 22265 pyruvate dehydrogenase phosphat 310
428734 BE303044 Hs 192023 NM 003757 Homo sapiens eukaryotic transi 309
423022 AA320525 Hs 201076 Hs 201076 ESTs 309
427648 AI376722 Hs 180062 Hs 180062 proteaso e (prosome, mxropain 308
404240 308
408989 AW361666 Hs 49500 Hs 49500 KIAA0746 protein 308
452835 AK001269 Hs 30738 NM.018087 Homo sapiens hypothetical prot 308
446506 AI123118 Hs 15158 (locuslmk)NM_016326 Homo εapienε chemok 308
402260 308
429671 BE378335 Hs 211594 Hs 211594 proteasome (prosome mxropain 308
409267 NM 012453 Hs 52515 NM.012453 Homo εapiens transducin (beta) 308
445937 AI452943 Hs 321231 (locuslιnk)NM_003779 Homo sapiens UDP Ga 307
431243 U46455 Hs 252189 NM.002999 Homo sapiens syndxan 4 (amphi 307
422611 AA158177 Hs 118722 (tocuslιnk)NM_004480 Homo εapiens fucosy 307
427647 W19744 Hs 180059 Hs 180059 Homo sapiens cDNA FU31360 fis 307
449644 AW960707 Hs 148324 Hs 148324 ESTs 307
448719 AA033627 Hs 21858 Hs 21858 senne (orcyεteine) proteinase 307
417457 AA378907 Hs 349326 Hs 349326 Homo sapiens cDNA FU30677 fis 307
454128 AL031259 Hs 367900 Hs 367900 programmed cell death 2 307
424927 AW973666 Hs 153850 Hs 153850 hypothetical protein C321D24 307
428144 BE269243 Hs 182625 Hs 182625 VAMP (vesicle aεsxiated membr 307
426440 BE382756 Hs 169902 NM.006516 Homo sapiens solute earner fa 306
426410 BE298446 Hs 305890 NM.138578 Homo sapiens BCL2 like 1 (BCL2 306
426812 AF105365 Hs 172613 NM.006598 Homo sapiens solute earner fa 306
435750 AB029012 Hs 4990 Hs 4990 KIAA1089 protein 306
421802 BE261458 Hs 108408 (tocuslιnk)NM_016022 Homo sapiens CGI 78 306
421905 AI660247 Hs 3260g Hs 32699 Homo sapiens Similarto RIKEN 306
430542 AI557486 Hs 119122 Hs 119122 πbosomal protein L13a 306
427268 X78520 Hs 174139 NM.001829 Homo εapiens chloπde channel 306
412525 AA581439 Hs 152328 Hs 152328 ESTs 306
422813 AV656571 Hs 121068 (lxuslιnk)NM_003270 Homo sapiens transm 305
441406 Z45957 Hs 7837 Hs 7837 phosphoprotein regulated by mito 305
408806 AW847814 Hε 75608 Hε 75608 tight junction protein 2 (zona 305
435730 AB020635 Hε 4984 Hs 4984 KIAA0828 protein 305
432871 NM.016142 Hs 279617 Hs 279617 hydroxysteroid (17 beta) dehyd 305
447783 AF054178 Hs 19561 NM.005001 Homo εapiens NADH dehydrogenas 305
426268 AF083420 Hs 168913 NM.003576 Homo sapiens seπne/threonme 305
450447 AF212223 Hs 25010 NM.018698 Homo εapiens hypothetical prot 305
427337 Z46223 Hs 176663 NM.000569 Homo sapiens Fc fragment of Ig 305
406363 305
439841 AF038961 Hs 6710 NM.004870 Homo sapiens mannose-P-dolicho 305
431738 AW237726 Hs 288549 NM.032828 Homo sapiens ubiquitin UBF-fl 304
447966 AA340605 Hs 105887 (lxuslιnk)NM_145252 Homo sapiens simila 304
439246 AI498072 Hs 351474 Hs 351474 Homo sapiens cDNA FU30002fis 304
419493 AF001212 Hs 90744 Hs 90744 proteasome (prosome, mxropain) 304
427597 D15049 Hs 179770 NM.002842 Homo sapiens protein tyrosine 304
430281 AI878842 Hs 237924 NM.016016 Homo sapiens CGI-69 protein (L 304
446620 AA128808 Hε 179902 (lxuslιnk)NM_022109 Homo sapiens CDw92 304
452865 A1924046 Hs 119567 Hs 119567 ESTs, Weakly similar to ALU1.H 304
422164 NM.014312 Hs 112377 Hs 112377 cortical thymocyte rxeptor (X 304
444301 AK000136 Hs 10760 NM.017680 Homo sapiens aspoπn (LRRclas 304
451455 AI937227 Hs 8821 NM.021175 Homo sapiens hepcidin antimicr 303
417777 AI823763 Hs 7055 Hs 7055 Homo sapiens cDNA FU33420fis, 303
417144 AA382104 Hs 81337 Hs 81337 Ixtin, galxtoside-binding, so 303
450825 AC005954 Hs 25527 (tocuslιnk)NM_014428 Homo sapienε tight 303
414774 X02419 Hs 77274 NM.002658 Homo sapiens plasminogen xtjv 303
409430 R21945 Hs 346735 Hs 346735 Homo sapienε, clone IMAGE 3881 303
440659 AF134160 Hs 327 NM.021101 Homo sapiens claudin 1 (CLDN1) 303
432268 BE311856 Hs 274230 Hs 2742303'-phosphoadenosιne δ'-phospho 303
438930 AW843633 Hs 343261 Hε 343261 histocompatibility (minor) 13 302
412599 AU076782 Hs 248267 (tocuεlιnk)NM_021126 Homo sapiens mercap 302
426788 U66615 Hs 172280 NM.003074 Homo sapiens SWI/SNF related, 302
425966 NM.001761 Hε 1973 NM.001761 Homo sapiens cyclin F (CCNF), 302
448847 AI587180 Hs 110906 Hs 110906 hypothetical protein BC004501 302
431236 AV656840 Hs 285115 NM.001560 Homo sapiens interleukin 13 re 302
414702 L22005 Hs 76932 NM.004359 Homo sapienε cell division eye 302
430024 AI808780 Hs 227730 NM.O00210 Homo sapienε integπn, alpha 6 302
424394 BE277024 Hs 146381 Hε 146381 RNA binding motif protein, X c 301
442993 BE018682 Hs 166196 Hs 166196 ATPase, Class I, type 8B, memb 301
437712 X04588 Hs 85844 Hs 85844 neurotrophic tyrosine kinaεe, r 301
410293 AK000047 Hs 61960 NM.018992 Homo sapiens hypothetical prot 301
454358 AW792876 Hs 288936 NM.031420 Homo sapiens mitochondπal nb 301
411531 AB014511 Hs 70604 Hs 70604 ATPase, Clasε II, type 9A 300
447032 AK000310 Hs 17138 (tocuεlιnk)NM_017755 Homo sapiens hypoth 3 00
414249 AI797994 Hs 279929 (lxuslιnk)NM_017510 Homo sapienε gp25L2 300
448440 AA173467 Hs 62402 Hε 62402 p21/Cdc42/Rx1-xtιvated kinase 300
423184 NM 004428 Hs 1624 NM.004428 Homo sapienε ephπn A1 (EFNA1) 300
419452 U33635 Hs 90572 Hs 90572 PTK7 protein tyrosine kinase 7 300
417878 U90916 Hs 82845 Hs 82845 Homo sapiens cDNA FU21930 fis 300 431884 AA521246 Hs.210792 Hs.210792:Homo sapiens cDNA FU366gi fis 3.00
425261 BE385099 Hs.355814 Hs.355814:Homo sapiens clone IMAGE:29333 3.00
445229 BE276013 Hε.343828 Hs.343828:Homo εapienε mRNA; cDNA DKFZp7 3.00
412146 M92444 Hs.73722 Hs.73722:APEX nuclease (multifunctional 2.99
437763 AA46g369 Hs.5831 Hs.5831 :tissue inhibitor of metaltoprote 2.99
406865 AI025931 Hs.181357 Hs.181357:laminin rxeptor 1 (67kD, ribo 2.99
425725 NM.012243 Hs.159322 (tocuslink)NM_012243:Homo sapiens solute 2.99
417259 AW903838 Hε.81800 Hs.81800:chondroitin sulfate protxglyca 2.98
453902 BE502341 Hs.3402 NM_139177:Homo sapiens chromosome 17 ope 2.98
432396 AW295956 Hs.11900 (l∞uslink)NM_032527:Homo sapiens hypoth 2.98
411358 R47479 Hε.94761 Hs.94761:KIAA1691 protein 2.98
453518 AW503205 Hs.27268 Hs.27268:Homo sapieπε cDNA: FU2ig33 fiε 2.98
448913 AA194422 Hs.22564 NM_004999:Homo sapiens myosin VI (MY06), 2.98
440943 AW082298 Hs.146161 NM_032331:Homo sapienε hypothetical prot 2.98
414013 AA766605 Hs.47099 NM 024642:Homo sapiens hypothetical prot 2.98
452124 AA454220 Hs.61170 Hs.61170:ESTs 2.98
416391 AI878927 Hs.79284 NM_002402:Homo sapiens mesoderm spxific 2.98
419092 J05581 Hs.89603 NM_002456:Homo sapienε mucin 1, transmem 2.97
426375 AK000507 Hs.169549 NM 017893:Homo sapienε εema domain, immu 2.97
437296 AA350994 Hs.20281 Hs.20281:MAPK phosphatase-7 2.97
407736 N41744 Hs.349326 Hs.349326:Homo εapienε cDNA FU30677 fis 2.97
443303 U67319 Hs.9216 NM_033340:Homo sapfens caspase 7, apopto 2.97
424756 AW504657 Hs.152931 (tocusiink)NM_002296:Homo sapiens lamin 2.97
430354 AA054810 Hs.239784 Hs.239784:scribble 2.97
417079 U65590 Hs.81134 (l∞uslink)NM_000577:Homo sapiens interi 2.97
425221 AV649864 Hs.155188 NM_005642:Homo sapienε TAF7 RNA polymera 2.97
414186 U33446 Hs.75799 Hs.7579g:protease, serine, 8 (prostasin) 2.97
432065 AA401039 Hs.2903 Hs.2903:protein phosphatase 4 (formerly 2.96
452012 AA307703 Hs.279766 (l∞uslink)NM_012310:Homo sapienε kinesi 2.96
412429 AV650262 Hε.75765 NM_002089:Homo sapiens GR02 oncogene (GR 2.96
452714 AW770994 Hs.30340 Hs.30340:hypothetical protein KIAA1165 2.96
429922 Z97630 Hs.226117 NM_005318:Homo sapiens H1 histone family 2.96
' 434931 AW968941 Hs.166254 Hs.166254:likely ortholog of rat vxuole 2.96
416293 BE244454 Hs.79162 Hs.79162:structure spxific rxognition 2.96
428781 AF164799 Hs.193384 Hs.193384:putatative 28 kDa protein 2.96
445350 AF052112 Hs.12540 NM_006330:Homo sapienε lysophoεpholipase 2.96
422396 W21872 Hε.7907 (tocuslink)NM_145059:Homo sapieπε L-fuco Z96
429597 NM 003816 Hs.2442 Hs.2442:a disintegnn and metalloprotein 2.95
421179 U72664 Hs.148495 NM_00281O:Homo sapiens proteasome (proso 2.95
417691 AU076610 Hs.82399 NM_007357:Homo sapiens component of olig 2.95
427715 BE245274 Hs.180428 Hs.180428:KIAA1181 protein 2.95
430589 AJ002744 Hs.246315 NM_017423:Homo sapiens UDP-N-xetyl-alph 2.95
409220 BE243323 Hε.51233 (tocuslink)NM_003842:Homo sapiens tumor 2.95
443883 AA114212, Hε.9930 Hs.9930:seriπe (or cysteine) proteinase 2.95
445720 AL040482 Hs.286173 Hs.286173:KIAA1595 protein 2.95
429583 NM.006412 Hs.209119 NM_006412:Homo sapiens 1-xyIglycerol-3- 2.95
427581 NM 014788 Hs.179703 NM_014788:Homo sapiens tripartite motif- 2.94
419193 D29643 Hs.34789 NM_005216:Homo εapienε dolichyl-diphoεph 2.94
419152 L12711 Hs.89643 (l∞usliπk)NM_001064:Homo sapiens transk 2.94
444824 AA843575 Hs.12056 NM_001671:Homo sapiens asiaioglycoprotei 2.94
431629 AU077025 Hs.265827 NM_022873:Homo sapienε interferon, alpha 2.94
425118 AU076611 Hs.154672 Hε.154672:methyleπe tetrahydrofolate deh 2.94
422010 AA302049 Hs.31181 Hε.31181:Homo εapiens cDNA: FU23230 fis 2.93
436075 BE090176 Hs.179902 NM_080546:Homo sapiens CDw92 antigen (CD 2.93
412338 AA151527 Hs.69485 (l∞uslink)NM_024661:Homo sapienε hypoth 2.93
413073 AL038165 Hε.75187 NM_014765:Homo sapiens transl∞ase of ou 2.93
412088 AI689496 Hs.108932 Hs.108932:ESTε 2.93
447140 AF070537 Hs.17481 NM_138391:Homo εapienε hypothetical prot 2.92
426746 J03626 Hs.2057 NM_000373:Homo εapienε undine moπophoεp 2.92
424291 AL120051 Hε.144700 NM_004429:Homo sapiens ephriπ-B1 (EFNB1) 2.92
417944 AU077196 Hs.82885 NM_000393:Homo sapiens collagen, type V, 2.92
428343 AL043021 Hs.12705 (l∞uslink)NM_145294:Homo sapienε simila 2.g2
435640 AF220053 Hs.54960 NM.018468:Homo sapiens uncharxterized h 2.92
451608 AA384525 Hs.26745 NM_01649g;Homo sapiens HSPC244 (MG&1337 2.92
434608 AA805443 Hs.179909 NM.024831 :Homo sapienε nuclear receptor 2.92
437186 AA338305 Hs.377816 Hs.377816:Homo sapiens cDNA FU36808 fis 2.91
429574 BE268321 Hs.208912 Hs.208912:hypothetical protein MGC861 2.91
438549 BE386801 Hs.21858 Hs.21858:serine (or cyεteine) proteinase 2.91
440246 W52010 Hε.191379 Hε.181379:ESTs 2.91
426924 BE222542 Hs.128782 Hs.128782:Homo εapienε cDNA FU31512 fiε 2.91
444193 Y17801 Hs.10574 Hs.10574:solute carrier family 2, (fxil 2.91
422030 X51416 Hs.110849 (locusliπk)NM_004451:Homo sapiens estrog 2.91
415938 BE383507 Hs.78921 NM_003488:Homo εapienε A kinase (PRKA) a 2.91
450167 AA446404 Hs.24563 NM.013248:Homo sapiens NTF2-like export 2.91
408815 AW957974 Hε.25485 (l∞uslink)NM_024599:Homo sapiens hypoth 2.91
414820 AA371931 Hε.77422 Hs.77422:prateolipid protein 2 (colonio 2.91
410013 AF067173 Hs.57904 Hs.57904:mago-nashi homolog, proliferati 2.91
444823 BE262989 Hs.12045 Hs.12045:C2f protein Z91
422197 AW974265 Hs.111632 Hs.111632:Lεm3 protein 2.90
432710 AA609685 Hs.278672 NM_005898:Homo εapfens membrane componen 2.90
405203 2.90
432465 D56165 Hs.275163 NM_002512:Homo sapiens πon-metastatic ce 2.90
412926 AI879076 Hs.75061 Hs.75061:mxrophage myristoylated alanin 2.90 455867 L12535 Hs.75551 (l∞uslink)NM_012425:Homo sapiens Ras su 2.90
402104 2.90
414814 D14697 Hs.77393 (tocuslink)NM_002004:Homo sapfens fames 2.90
442739 NM 007274 Hs.8679 (l∞uslinkJNM 007274:Homo sapiens cytoso 2.90
456157 AW979153 Hs.336881 Hs.336881 :ESTs 2.90
429505 AW820035 Hs.278679 NM_033274:Homo εapiens a disintegnn and 2.89
430567 NM 003028 Hs.244542 Hs.244542:Homo sapiens cDNA FLJ38908 fis 2.89
437822 AW450485 Hs.4437 NM_000991:Homo sapiens ribosomal protein 2.89
438543 AA810141 Hs.192182 Hε.192182:ESTs 2.89
426158 NM.001982 Hs.199067 NM.001982:Homo sapienε v-erb-b2 erythrab 2.89
441455 AJ271671 Hs.7854 NM_014437:Homo sapfens solute carrier fa 2.89
420166 AW732276 Hs.95583 NM.012330:Homo sapienε tranεmembrane 4 ε 2.89
415674 BE394784 Hs.78596 NM_002797:Homo sapiens proteasome (proso 2.89
409591 AA532963 Hs.gi00 Hs.9100:hypothetical gene supported by A 2.89
418062 AW630656 Hs.83383 NM_006406:Homo sapiens peroxiredoxin 4 ( 2.89
436540 BE397032 Hs.14468 NM_020230:Homo sapiens peter pan homolog 2.89
426675 AW084791 Hs.133122 Hs.133122:hy pothetical protein FU14524 2.89
417018 M16038 Hs.80887 Hs.80887:v-yeε-1 Yamaguchi εarcoma viral 2.89
421684 BE281591 Hs.106768 NM_018120:Homo εapiens hypothetical prot 2.88
429404 NM 005738 Hs.10706 NM_005738:Homo sapfens ADP-ribosylation 2.88
411030 BE387193 Hs.67896 (lxuslink)NM_007346:Homo sapiens opioid 2.88
413822 R08950 Hs.272044 Hs.272044:ESTs, Weakly similar to hypoth 2.88
438085 R52518 Hs.7967 Hs.7967:ESTs, Weakly similar to extensin 2.88
409132 AJ224538 Hs.50732 NM_005399:Homo sapiens protein kinase, A 2.88
440490 AW513684 Hs.7218 Hs.7218:xetyl-Coenzyme A synthetase 2 ( 2.87
431498 AK001777 Hs.258551 NM.012100:Homo sapiens aspartyl aminopep 2.87
423570 AW838306 Hε.120819 NM.018344:Homo sapfens hypothetical prot 2.87
448569 BE382657 Hε.21486 Hs.21486:signal transducer and xtivator 2.87
451711 AK000461 Hs.26890 NM.017829:Homo sapiens cat eye syndrome 2.87
442643 U82756 Hs.374g73 (locuslink)NM_004697:Homo εapiens PRP4 p 2.87
447887 AA114050 Hs.211610 NM_001228:Homo sapiens caspase 8, apopto 2.87
421178 BE267994 Hs.102419 Hs.102419:ziπc finger protein 2.87
443329 BE262943 Hs.9234 NM_032635:Homo εapienε εeven transmembra 2.87
416448 L13210 Hs.79339 NM_005567:Homo sapiens Ixtin, galactosi 2.87
453145 R63438 Hs.183454 Hs.183454:Homo sapfens cDNA FU14883 fis 2.86
427775 R26944 Hs.180777 Hs.180777:Homo sapiens mRNA; cDNA DKFZpδ 2.86
424732 D80001 Hs.152629 Hs.152629:KIAA0179 protein 2.86
426125 X87241 Hs.166994 Hs.166g94:FAT tumor suppressor homolog 1 2.86
450273 AW296454 Hs.24743 Hs.24743:hypothetical protein FU20171 2.86
407082 Z47055 2.86
450038 AA005159 Hs.188489 Hs.188489:ESTs 2.86
' 457274 AW674193 Hs.227152 NM_016391:Homo εapienε hypothetical prot 2.85
417831 H16423 Hs.82685 Hs.82685:CD47 antigen (Rh-related antige 2.85
417824 AA084788 Hs.82646 NM_006145:Homo sapiens DnaJ (Hsp40) homo 2.85
426989 AI815206 Hs.100293 Hs.100293:O-linked N-xetylglucosamine ( 2.85
434916 AF161383 Hs.284207 Hs.284207:hypothetical protein BC003515 2.85
412664 AA421404 Hε.346868 NM_006824:Homo sapienε EBNA1 binding pro 2.85
414172 AW054324 Hs.75790 (tocuslink)NM_002642:Homo sapiens phosph 2.85
409504 AA304061 Hs.699 Hε.699:peptidylproIyl iεomerase B (cyclo 2.84
430920 H05430 Hs.288433 NM_016522:Homo sapiens neurotrimin (HNT) 2.84
418462 BE001596 Hs.85266 Hs.85266:integrin, beta4 2.84
442199 BE277633 Hs.372542 NM_004879:Homo εapienε etopoεide-induced 2.84
406710 AI708347 Hs.184014 Hs.184014:ribosomal protein L31 2.84
433435 BE545277 Hs.340959 NM_005726:Homo εapfens Ts translation el 2.84
415402 AA164687 Hs.177576 Hs.177576:mannosyl (alpha-1,3-)-glycopro 2.84
448730 AB032983 Hs.21894 Hs.21894:KIAA1157 protein 2.84
433027 AF191018 Hε.279923 (lxuslink)NM_014366:Homo sapiens putati 2.84
449090 AK001735 Hs.22983 NM_020121:Homo sapiens UDP-glucose ceram 2.84
439737 AI751438 Hs.41271 Hs.41271:Homo sapiens mRNA full length i 2.84
403912 2.84
423225 AA852604 Hs.125359 NM 006288:Homo sapfens Thy-1 cell surfx 2.84
458376 AB023179 Hs.9059 Hs.9059:KIAA0962 protein 2.84
420211 AF052693 Hε.198249 NM_005268:Homo sapiens gap junction prot 2.84
452518 AA280722 Hs.24758 Hs.24758:Homo sapiens cDNA FU32068 fis, 2.84
418127 BE243982 Hs.83532 (l∞uslink)NM_002389:Homo sapienε membra 2.83
448489 AI523875 R45782:Ha616-f Adult heart, Clontxh Hom 2.83
426194 T50872 Hs.2001 NM_001061:Homo sapfens thromboxane A syn 2.83
422129 AU076635 Hε.1478 NM_000185:Homo sapiens serine (orcystei 2.83
437651 BE560672 Hs.13543 (l∞usliπk)NM_145214:Homo sapiens tripar 2.83
415173 AW501735 Hs.180059 Hs.180059:Homo sapiens cDNA FU31360 fis 2.83
408201 AK000568 Hs.43654 NM.017882:Homo sapfens ceroid-lipofuscin 2.83
444758 AL044878 Hs.11899 NM_000859:Homo εapienε 3-hydroxy-3-methy 2.83
423323 AI951628 Hs.127007 NM_003740:Homo εapfens potassium channel 2.83
439720 AI935202 Hs.31181 Hs.31181:Homo sapiens cDNA: FU23230 fis 2.83
435550 AI224456 Hs.324507 Hs.324507:hypothetical protein FU20986 2.83
425907 AA365752 Hs.155965 Hε.155965:ESTs 2.83
426234 BE314534 Hs.168159 Hs.168159:bifunctional apoptosis regulat 2.82
427640 AF058293 Hs.180015 NM.001355:Homo sapiens D-dopxhrome taut 2.82
433233 AB040927 Hs.301804 Hs.301804:KIAA1494 protein 2.82
415697 AI365603 Hs.279696 Hs.279696:DKFZP566l1024 protein 2.82
441321 H17182 Hs.7771 NM_007273:Homo sapiens repressor of estr 2.82
430040 AW503115 Hε.227823 NM_014287:Homo sapiens pM5 protein (PM5) 2.82
449954 AA641636 Hε.37477 Hs.37477:ESTs, Weakly similar to T46220 2.82 427022 AW245838 Hs 173255 NM.004596 Homo sapiens small nuclear πb 2.82
410047 AI167810 Hs 379753 Hs 379753 Homo sapiens cDNA FU33176 fis 282
400845 281
418501 AW843822 Hs 199961 Hs 199961 ESTs, Weakly similar to hypoth 281
418140 BE613836 Hs 83551 (tocuslιnk)NM_002403 Homo sapiens microf 281
422032 AA476866 Hs 110857 NM.016310 Homo sapienε polymerase (RNA) 281
419768 T72104 Hs93ig4 Hε 93194 apolipoprotein A I 281
436673 AF201931 Hs5268 Hε 5268 zinc finger, DHHC domain contain 281
421140 AA298741 Hε 102135 NM.006280 Homo εapiens signal sequence r 281
450126 BE018138 Hs 24447 (locuslιnk)NM_005866 Homo sapiens type I 281
439018 AW300887 Hs 26638 NM.031457 Homo sapiens membrane spanning 281
433061 AW068033 Hs296422 (l∞uslιnk)NM_025233 Homo sapiens πucleo 281
400278 Hs2280 NM.002950 Homo sapiens nbophoπn I (RPN 281
407338 AA773213 Hs91202 Hs 91202 Homo sapienε cDNA FU25946 fis, 281
410240 AL157424 Hs61289 Hs6128gsynaptojanιπ 2 280
423880 BE278111 Hs 134200 Hs 134200 DKFZP564C186 protein 280
422098 H03117 Hs 111497 Hs 111497 neuronal protein 173 280
426680 AA320160 Hs 171811 NM.001625 Homo sapiens adeπylate kinase 280
437672 AW748265 Hs5741 NM.016230 Homo sapiens flavohemoprotein 280
456602 AA411607 Hs 118964 NM.017660 Homo sapiens hypothetical prot 280
457329 AI634860 Hs 359682 (l∞uslιnk)NM_016442 Homo sapiens type 1 280
426437 BE076537 Hs 169895 Hs 169895 ubiquitin-conjugating enzyme E 279
412627 BE391959 Hs74276 Hs 74276 chloπde intracellular channel 279
452695 AW780199 Hs 30327 NM.003668 Homo sapiens mitogeπ xtivated 279
409531 BE384319 Hs 54702 (tocuslιnk)NM_007255 Homo sapiens xylosy 279
448988 Y09763 Hs22785 NM.021987 Homo εapienε gamma-aminobutyπ 279
417627 AF090922 Hs 152738 NM.016050 Homo sapiens mitxhondπal πb 279
419846 NM 015977 Hs 285681 NM.032951 Homo sapiens Williams Beuren s 279
412969 AI373162 Hs75103 NM.003406 Homo sapienε tyrosine 3-monoox 279
424867 AI024860 Hs 153591 NM.005787 Homo sapiens Not56 (D melanog 279
410600 AW575742 Hs 351676 Hs 351676 Homo sapiens cDNA FU25921 fis 279
451452 BE560065 Hs 26433 NM.001382 Homo sapiens dolichyl-phosphat 279
407844 AW073716 Hs8037 (l∞uslιnk)NM_005723 Homo sapiens tetras 279
448752 AA593867 Hs300842 NM.024820 Homo sapiens KIAA1608 protein 279
419235 AW470411 Hs 288433 NM.016522 Homo sapiens neurotnmiπ (HNT) 278
407754 AA527348 Hs 288967 Hs 288967 Homo sapiens, similar to RIKEN 278
422282 AF019225 Hs 114309 (lxuslιnk)NM_003661 Homo sapiens apolip 278
414181 AK000476 Hs 75798 NM 016470 Homo sapiens chromosome 20 ope 278
418869 AW516565 AA229762 nc49f01 r1 NCI_CGAP_Pr3 Homosa 278
419444 NM.002496 Hs 90443 NM.002496 Homo sapiens NADH dehydrogenas 278
430250 NM 016929 Hs 283021 NM 116929 Homo sapiens chloπde intrxel 278
412760 AW379030 Hs41324 Hs 41324 ESTs 278
423013 AW875443 Hs 22209 Hs 22209 secreted modular calcium bindin 278
440703 H61001 Hs 171802 Hs 171802 Homo sapiens, clone IMAGE 3956 278
447402 H54520 Hs351327 (tocus!ιnk)NM_017828 Homo sapiens hypoth 278
417896 AA379770 Hs 82890 Hs 82890 defender against cell death 1 278
422051 AW327546 Hs 111024 (tocuslιnk)NM_005884 Homo sapiens solute 278
450607 AL050373 Hs 25213 NM.015677 Homo sapiens hypothetical prot 278
419757 AA773820 Hs63970 Hε 63970 ESTε 277
409932 AI376750 Hs57600 NM.O01283 Homo sapiens adaptor-related p 277
408044 BE206939 Hs42287 NM.001952 Homo sapiens E2F transcnption 277
430014 H59354 Hs374303 (l∞uslinkJNM 144691 Homo sapiens hypoth 277
451690 AW451469 Hs 209990 Hs 209990 ESTs 277
446950 AA305800 Hs5672 (lxuslιnk)NM_030799 Homo εapienε golgi 277
444207 AI565004 Hs 374415 Hs 374415 ESTs 277
417089 H52280 Hs 18612 Hs 18612 Homo sapiens cDNA FU21909fis 277
445985 BE621800 Hs 29444 Hs 29444 putative small membrane protein 277
425978 BE253927 Hs 24983 Hs 24983 hypothetical protein from EUROI 277
422753 AI928995 Hs 1575 Hs 1575 small nuclear πbonucleoprotein 277
449051 AW961400 Hs 333526 NM.032339 Homo sapiens hypothetical prot 277
450701 H39960 Hs288467 Hs 288467 Homo sapienε cDNA FU12280 fis 277
412890 T85247 Hs 351875 NM.004374 Homo sapienε cytxhrome c oxid 277
415752 BE314524 Hs78776 NM.012342 Homo sapiens putative transmem 276
427609 AK000436 Hs 179791 NM 017817 Homo εapieπs RAB20, member RAS 276
450770 AA019924 Hs 28803 Hs 28803 ESTs 276
419594 AA013051 Hs 91417 (tocuslιnk)NM_007027 Homo sapiens topois 276
450876 AF189062 Hs 285976 (tocuslιnk)NM_013384 Homo sapiens LAG1 1 276
417767 BE242241 Hs 82542 NM.001637 Homo sapiens xyloxyxyl hydro 276
439968 AA224760 Hs153 NM 000971 Homo sapiens πbosomal protein 276
426520 BE545684 Hε343566 Hs 343566 KIAA0251 protein 275
441028 AI333660 Hε 17558 Hs 17558 Homo sapiens, clone IMAGE 40704 275
445033 AV652402 Hs72901 NM.078487 Homo sapiens cyclm-dependent 275
418478 U38945 Hs1174 NM.000077 Homo sapiens cyclm-dependent 275
428157 AI738719 Hs 198427 NM.000189 Homo sapienε hexokmase 2 (HK2 275
416178 AI808527 Hs 192822 NM.030940 Homo sapiens protein phosphata 275
435025 T08990 Hs4742 Hs 4742 GPAA1P anchor attxhment protein 275
421917 AB028943 Hs 109445 Hs 109445 hyper ethylated in cancer 2 275
406621 X57809 Hs 181125 Hs 181125 immunoglobulin lambda tocus 275
408196 AL034548 Hs43627 NM.006943 Homo sapiens SRY (sex determiπ 275
412600 L28824 Hs74101 Hs 74101 spleen tyrosine kinase 275
452806 AW014549 Hs 58373 Hs 58373 ESTs 275
451356 AA748418 Hs 33368 Hs 33368 hypothetical protein FU11175 275
421643 BE281170 Hs 106357 NM.O07126 Homo sapienε valoεin-contamin 274 423527 AI206965 Hε 105861 (tocuslιnk)NM_024712 Homo sapiens engulf 274
428000 R35145 Hs 291904 Hs 291904 xceεsory protein BAP31 274
441565 AW953575 Hs 303125 Hε 303125 p53-ιnduced protein PIGPC1 274
450247 AF123303 Hs 24713 NM.013386 Homo sapiens hypothetical prot 274
422691 NM 003365 Hs 119251 NM.003365 Homo sapiens ubiquinol-cytochr 274
440457 BE387583 Hs 21321 (locuslιnk)NM_145808 Homo sapiens granul 274
422675 BE018517 Hs 119140 NM.001970 Homo sapienε eukaryotic tranεl 274
428428 AL037544 Hs 184298 NM.001799 Homo εapieπs cyclm-dependent 273
423598 BE247600 Hs 377968 NM.020400 Homo sapiens G protein-coupled 273
428297 AA236201 Hs 183583 NM.030666 Homo sapiens seπne (orcystei 273
421921 H83363 Hs 355993 NM.012456 Homo εapienε transtocase of in 273
403217 273
423671 AW860155 Hs 234101 Hε 234101 Homo sapiens, similar to choli 273
418733 AA227714 Hs 374897 Hs 374897 Homo sapiens cDNA FU36874 fis 273
400275 Hs 4888 NM.006513 Homo sapiens seryl tRNA syπthe 273
445084 H38914 Hs 250848 Hs 250848 Homo sapiens cDNA FU14761 fis 273
411872 AW327356 Hs90918 Hs 90918 chromosome 11 open reading tram 273
403483 273
438119 AWg63217 Hs 203961 Hs 203961 ESTs, Weakly similar to hypoth 273
422009 AI742845 Hs 110713 NM 003472 Homo sapiens DEK oncogene (DNA 273
436995 AI160015 Hs 125489 Hs 125489 KIAA1961 protein 273
400509 273
429305 AF095727 Hs 287832 Hs 287832 myelm protein zero-like 1 273
445899 AI263736 Hs 145626 Hs 145626 Homo sapiens, Similar to hypot 272
453557 AA522464 Hs 285996 NM.024956 Homo sapiens hypothetical prot 272
446859 A1494299 Hs 16297 NM.005694 Homo sapiens COX17 homolog, cy 272
424439 AA579635 Hs 1770 Hs 1770 ligase I, DNA, ATP dependent 272
437809 AL137723 Hs 5855 Hs 5855 Homo sapiens mRNA, cDNA DKFZp434 272
428466 AF151063 Hs 184456 NM.016486 Homo sapiens hypothetical prot 271
445176 AI878907 Hs 12379 NM.001419 Homo sapienε ELAV (embryonic I 271
438000 AI825880 Hs 5985 Hε 5985 non kinase Cdc42 effector protei 271
429359 W00482 Hs2399 NM.004995 Homo sapiens matnx metallopro 271
427782 AI956052 Hs 115960 NM.024036 Homo sapienε hypothetical prot 271
415169 W42913 Hs78089 NM.004231 Homo sapiens ATPase, H+ transp 271
400277 Hs2280 NM.002950 Homo sapienε nbophoπn I (RPN 271
426263 A1908774 Hs 259785 Hε 259785 carnitme palmitoyltranεferaεe 271
445515 BE388665 Hε 179999 Hs 179999 Homo sapienε, clone IMAGE 3457 271
416076 BE243085 Hs 80680 Hs 80680 major vault protein 271
441238 A1372555 Hs 322456 NM.032039 Homo sapienε hypothetical prat 271
420511 AF052692 Hs 98485 NM.024009 Homo εapiens gap junction prot 271
424865 AW956282 Hs 144609 NM.080652 Homo sapiens similarto RIKEN 271
421808 AK000157 Hs 108502 NM.017688 Homo sapienε hypothetical prot 271
412973 L37368 Hs75104 Hε 75104 RNA binding protein S1, εeπne 270
410113 AWgg6564 Hs 250824 Hs 250824 Homo sapienε cDNA FU23435 fi 270
413092 AA126856 Hs 118665 Hε 118665 ESTs 270
447096 BE539199 Hs 62112 (tocuslιnk)NM_003457 Homo sapiens zinc f 270
450493 M93718 Hs 166373 Hs 166373 nitπc oxide synthaεe 3 (endot 270
413745 AW247252 Hs 75514 NM.000270 Homo sapiens nucleoside phosph 270
450747 AI064821 Hε 129953 Hs 129953 Ewing sarcoma breakpoint regio 270
436042 AF284422 Hs 119178 (lxuslιnk)NM_020246 Homo εapienε cation 270
432981 NM 002733i Hs 3136 Hε 3136 protein kinase, AMP-xtivated, g 270
431341 AA307211 Hs 251531 NM.002789 Homo sapienε proteasome (proso 270
408204 AA454501 Hs43666 NM_007070 Homo sapiens protein tyrosine 270
416770 AW163570 Hs79768 NM.014740 Homo sapiens Kl AA0111 gene pro 270
447507 H596g6 Hs 18747 NM.005837 Homo sapiens POP7 (proceεsing 270
424500 AF040704 Hs 149443 (l∞uslιnk)NM_007022 Homo sapiens putati 269
414237 BE536554 Hs 278270 Hs 278270 unxtive progesterone receptor 269
400231 Hs 169476 NM.002046 Homo sapiens glyceraldehyde 3- 269
431209 NM.001533 Hs2730 Hs 2730 heterogen∞us nuclear πbonucleo 269
444118 AA458542 Hs 10326 NM.007263 Homo sapienε coatomer protein 269
424608 X80695 Hs 151134 Hs 151134 oxidase (cytochrome c) assembl 269
418546 AA224827 AA224827 nc32g04 s1 NCI_CGAP_Pr2 Homo sa 269
440002 AW769844 Hs 111222 Hs 111222 hypothetical protein FU22875 269
449957 D31365 Hs 24220 (l∞uslιnk)NM_016478 Homo sapiens scotin 269
432920 U37689 Hs3128 NM.006232 Homo sapiens polymerase (RNA) 269
450306 AL080080 Hs 24766 NM.030755 Homo sapienε thioredoxin domai 269
429544 BE299343 Hs2430 NM.005097 Homo sapiens transcnption fx 268
428582 BE336699 Hs 185055 Hs 185055 BENE protein 268
445139 AB037848 Hs 12365 Hs 12365 syπaptotagmm XIII 268
453905 NM.002314 Hs 36566 NM.016735 Homo sapiens UM domain kinase 268
418883 BE387036 Hs 1211 NM.001611 Homo sapiens xid phosphatase 268
420957 X98743 Hs 100555 Hs 100555 DEAD/H (Asp-Glu Ala-Asp/His) b 268
418187 NM 004604 Hs 83734 NM.004604 Homo sapienε εyntaxin 4A (plx 268
409533 AW96g543 Hs 144609 NM.080652 Homo sapiens similar to RIKEN 268
433184 AA147979 Hs 285005 NM.020243 Homo sapienε translxase of ou 268
455303 AW892049 BE066891 PM3-BT0338-211299-002-e12 BT033 268
452600 AI910842 Hs 103381 Hs 103381 ESTs, Weakly similar to hypoth 268
415410 AF037332 Hs 278569 NM.014748 Homo sapienε KIAA0064 gene pro 267
426432 AF001601 Hs 169857 NM.000305 Homo εapienε paraoxoπase 2 (PO 267
435049 AL122067 Hs4746 NM.021941 Homo sapienε hypothetical prot 2.67
450528 NM 014072 Hs 25063 NM.031268 Homo sapiens PRO0461 protein ( 267
433339 AF019226 Hs 8036 NM.004283 Homo sapiens RAB3D, member RAS 267
408783 AF192522 Hs47701 NM.013380 Homo sapiens NPC1 (Niemann Pic 267 451798 BE297567 Hs 27047 Hs 27047 hypothetical protein FU20392 267
427716 L38951 Hs 180446 Hs 180446 karyophenn (importm) beta 1 267
436319 H90727 Hs 5123 Hs 5123 hypothetical protein BC008246 267
415116 AA160363 Hs 269956 Hs 269956 ESTs 267
425838 NM.014071 Hs 159613 NM.014071 Homo sapiens nuclear rxeptor 266
418706 U73524 Hs 87465 NM.006831 Homo sapiens ATP/GTP binding p 266
410165 BE560228 Hs 71869 NM.013258 Homo sapiens apoptosis associa 266
410134 U68140 Hs 58g27 (tocuslιπk)NM_002533 Homo sapiens nuclea 266
430066 AI929659 Hε 237825 Hs 237825 εignal recognition particle 72 266
425910 AA830797 Hε 184760 NM.005760 Homo sapiens CCAAT box binding 266
427954 J03060 Hs 247551 NM 002455 Homo sapiens etaxiπ 1 (MTX1) 266
439971 32474 Hs 301746 Hs 301746 Homo sapiens cDNA FU37267 fis 266
438449 AK001333 Hs 6216 Hs 6216 DnaJ (Hsp40) homolog, εubfamily 266
435806 A1686379 Hs 110796 (tocuεlmk)NM_020150 Homo sapiens SAR1 p 266
433387 L76528 Hs 3260 NM.000021 Homo sapiens presenilin 1 (Alz 266
447101 NM 014521 Hs 17667 (locus πk)NM_014521 Homo sapienε SH3-do 266
444099 D87432 Hs 10315 NM.003983 Homo εapieπs solute earner fa 266
417821 BE245149 Hs 82643 NM.002822 Homo sapiens protein tyrosine 266
418529 AW005695 Hs 250897 Hs 250897 TRK-fused gene 265
426025 AW138330 Hs 17558 Hs 17558 Homo sapiens clone IMAGE 40704 265
420187 AK001714 Hs 95744 NM.019028 Homo sapiens hypothetical prot 265
408150 BE620274 Hs 43112 Hs 43112 Homo sapiens mRNA, cDNA DKFZp43 265
444395 N66148 Hs 11125 (locuslιnk)NM_014041 Homo sapienε εignal 265
431222 X56777 Hs 273790 NM 007155 Homo sapiens zona pellucida gl 265
406790 AA293303 Hε 356342 Hs 356342 ESTs, Highly similar to 211320 265
440708 AF038962 Hs 7381 Hs 7381 voltage-dependent aπion channel 265
416526 H61082 Hs 14743 Hs 14743 ESTs 265
413995 BE048146 Hs 75671 NM.004603 Homo sapiens syntaxin 1 A (brai 265
424908 AW513963 Hs 39143 Hs 39143 hypothetical protein MGC13125 265
442110 AF113008 Hs 8102 NM.001023 Homo sapiens πbosomal protein 265
452882 AW972990 Hs 196270 NM 030780 Homo sapiens folate traπsporte 265
406862 AW150807 Hs 356262 Hs 356262 ESTs, Highly similar to A31233 264
451295 AI557212 Hs 17132 Hs 17132 ESTs 264
448428 AF282874 Hs 21201 NM.015480 Homo sapiens nxtin 3 (DKFZP56 264
426611 BE178050 Hs 171271 NM.001904 Homo sapiens catenm (cadhenn 264
426216 N77630 Hs 13895 Hs Ϊ3895 Homo sapienε cDNA FU11654 fis, 264
407223 H96850 H96850 yw03b12 s1 Soares melaπxyte 2NbH 264
427725 U66839 Hs 180533 NM.002756 Homo sapiens mitogeπ-xtivated 264
420157 AA857991 Hs 123106 Hs 123106 ESTs 264
428471 X57348 Hs 184510 Hs 184510 stratifin 264
451544 AK000429 Hs 26570 NM.017814 Homo sapiens hypothetical prot 264
413245 BE244334 Hs 75249 Hs 75249 ADP-πbosylation factor-like 6 264
415020 BE249915 Hs 293533 Hs 293533 Homo sapiens cDNA FU37093 fis 264
437193 BE259190 Hs 289721 Hs 289721 growth arrest specific 5 264
418684 U82987 Hs 87246 NM.014417 Homo sapiens BCL2 binding comp 264
410668 BE379794 Hs 159651 NM.014452 Homo sapiens tumor nxrosis fa 264
436183 AI146327 Hs 334802 (locuslιnk)NM_024718 Homo sapieπε hypoth 264
441226 BE563042 Hs 118820 Hs 118820 hypothetical protein BC007882 264
432788 AA521091 Hs 178499 Hs 178499 HSPC063 protein 264
432746 AA564512 Hs 372775 Hs 372775 Homo sapiens, clone IMAGE 3946 264
450377 AB033091 Hs 355925 Hs 355925 KIAA1265 protein 264
434633 AI189587 Hs 120915 Hs 120915 ESTs 264
424707 BE061914 Hs 10844 Hs 10844 leuc e-πch alpha-2-glycoprote 264
427600 AW630918 Hs 179774 Hs 179774 proteasome (prosome, mxropain 263
446522 NM.003876 Hs 15186 NM.003876 Homo sapiens putative receptor 263
436906 H95990 Hs 181244 Hs 181244 major histocompatibilitycompl 263
410701 AF198620 Hs 10283 NM.005105 Homo sapiens RNA binding motif 263
410182 NM 001983 Hs 59544 NM.001983 Homo sapiens excision repairc 263
406716 AW148546 Hs 169476 Hs 169476 glyceratdehyde-3-phosphate deh 263
430308 BE540865 Hs 238990 NM.O04O64 Homo sapiens cyclm-dependent 263
431074 BE072772 Hs 8997 Hs 8997 Sad1 unc 84 domain protein 1 263
412867 AU076861 Hs 74637 Hs 74637 tests enhanced gene transcπpt 263
440524 R71264 Hs 16798 Hs 16798 Homo sapiens mRNA, cDNA DKFZp56 263
435968 AW161481 Hs 111577 (l∞uslιnk)NM_030926 Homo εapiens integr 263
422672 X12784 Hs 119129 NM.001845 Homo sapiens collagen, type IV 263
447528 AI612027 Hs 76277 NM.138393 Homo sapiens hypothetical prot 263
406774 AW518383 Hs 177592 Hs 177592 πboεomal protein, large, P1 263
43g755 AW748482 Hs 77873 Hε 77873 B7 homolog 3 263
435311 W86610 Hs 185736 Hs 185736 ESTs 263
428699 AW578252 Hs 190161 Hs 190161 LR8 protein 262
410678 BE540516 Hs 378825 Hs 378825 Homo sapiens cDNA FU37850 fis 262
414839 X63692 Hs 77462 (tocuslιnk)NM_001379 Homo sapiens DNA (c 262
443217 NM.001545 Hs 9078 Hs 9078 immature colon carcinoma traπscr 262
448749 AW859679 Hε 21902 Hε 21902 Homo εapiens clone 25237 mRNA s 262
450009 AI399947 Hs 166486 Hs 166486 Homo sapiens cDNA FU11432 fis 262
407687 AK002011 Hs 37558 NM.018339 Homo sapiens hypothetical prot 262
442232 AI357813 Hs 337460 Hs 337460 ESTs, Highly similar to HYEP.H 262
419625 U91616 Hs 182885 NM.004556 Homo sapiens nuclear fxtor of 262
416114 AI695549 Hs 183868 Hs 183868 glucuronidase, beta 262
439437 AI207788 Hs 343628 Hs 343628 sialyltransferase 4B (beta-gal 261
408452 AA054683 Hε 222728 Hε 222728 Homo sapiens cDNA FU39004 fis 261
443142 AI696513 Hε 108705 Hs 108705 protein phosphatase 2 (former! 261
426152 BE299190 Hs 167246 Hs 167246 P450 (cytochrome) oxidoredu a 261 419667 AU077005 Hs.92208 NM 003815:Homo εapiens a disintegrin and 2.61
415072 BE253687 Hs.77876 Hs.77876:hypothetioal gene MGC19595 2.61
406670 W79632 Hs.256301 Hs.256301 hypothetical protein MGC13170 2.61
403399 2.61
419579 W49529 Hs.296200 NM_023948:Homo sapiens hypothetical prot 2.61
437202 AA326110 Hs.374481 Hε.374481 :ESTs, Weakly similar to T34549 2.61
414020 NM 002984 Hs.75703 NM_002984:Homo sapiens small inducible c 2.61
421295 AW081061 Hs.103180 Hs.Tθ3180:DC2 protein 2.61
446488 AB037782 Hs.15119 Hs.15119:KIAA1361 protein 2.61
442504 BE503373 Hs.334335 NM 022484:Homo sapfens hypothetical prot 2.60
448204 AI475124 Hε.170561 Hs.170561:ESTs 2.60
449175 AJ005892 Hs.23170 (tocuslink)NM_012280:Homo sapiens FtsJ h 2.60
411201 T74588 Hs.8509 Hε.850g;ESTε, Weakly similar to C3HU com 2.60
424805 AF230904 Hs.153260 NM_031892:Homo sapfens SH3-domain kinase 2.60
425421 L11669 Hs.157145 Hs.157145:tetrxycline transporter-like 2.60
422739 H20106 Hs.119591 (tocuslink)NM_004069:Homo sapfens adapto 2.60
450858 C18458 Hs.25597 Hs.25597:elongation of very long chain f 2.59
443195 BE148235 Hs.193063 Hs.193063:Homo εapiens cDNA FLJ14201 fis 2.59
430504 H52761 Hs.44095 Hs.44095:cycliπ M3 2.59
439578 AW263124 Hs.350547 NM_024665:Homo sapiens nuclear rxeptor 2.59
416041 AA345547 Hs.53263 (lxuslink)NM.024647:Homo sapiens nuclx 2.59
451920 AA224483 Hs.27239 Hs.27239:zinc finger, DHHC domain contai 2.59
414163 BE262310 Hs.75782 NM_001521:Homo sapienε general transcrip 2.59
422140 BE295918 Hs.112193 (l∞uslinkJNM 025259:Homo sapiens chromo 2.59
452817 AA322859 Hs.284275 Hs.284275:p21 (CDKNIA)-xtivated kinase 2.59
413353 AW293542 Hs.75309 Hs.75309:eukaryotic translation eloπgati 2.59
421700 BE515018 Hs.107014 NM.016641 :Homo sapiens membrane interxt 2.59
410801 BE275469 Hs.66493 NM.016430:Homo sapienε Down syndrome cri 2.59
440511 AF132959 Hs.7236 NM_015953:Homo sapiens eNOS interacting 2.59
407887 AA57g668 Hs.41072 (locuslink)NM_004568:Homo sapiens serine 2.59
425356 BE244879 Hs.15503g NM_005541:Homo sapfens inositol polyphoε 2.59
408102 U46351 Hs.621 Hs.621 :lectin, galxtoside-binding, solu 2.59
417952 AI192838 Hε.173135 Hs.173135:dual-εpxificity tyrosine-(Y)- 2.59
433053 BE301909 Hs.27gg52 NM_015917:Homo sapiens glutathione S-tra 2.59
450935 BE514743 Hs.379039 NM_005851:Homo sapienε tumor suppressor 2.59
417891 W79410 Hs.82887 (l∞uslink)NM_021959:Homo sapienε protei 2.59
438364 AK000860 Hs.6191 NM_020441:Homo εapfens coronin, xlin-bi 2.59
430976 AA505112 Hs.2829gθ NM_033550:Homo sapiens chromosome 20 ope 2.58
444838 AV651680 Hs.208558 Hs.208558:ESTε 2.58
416435 AI431301 Hs.374897 Hε.374897:Homo εapienε cDNA FU36874 fis 2.58
415444 BE247295 Hs.78452 Hs.78452:solute carrier family 20 (phosp 2.58
452222 AW806287 Hs.21432 Hs.21432:SEXgene 2.58
400541 2.58
444309 U83236 Hs.10803 Hs.10803:calcium and integnn binding 1 2.58
416116 H51847 Hs.99858 Hs.99858:ribosomal protein L7a 2.58
418629 BE247550 Hs.86859 (lxuslink)NM 005310.Homo sapiens growth 2.58
432996 AF105025 Hε.279901 Hs.279801:PTD009 protein Z57
426781 AL048967 Hs.172207 (tocuslink)NM_007363:Homo sapiens non-PO 2.57
452636 BE615074 Hs.145279 Hs.145279:SET transl∞ation (myeloid leu 2.57
406851 AA609784 Hs.3523g2 Hs.352392:major histocompatibility compl 2.57
447674 BE270640 Hs.19192 NM_001798:Homo sapiens cyclin-dependeπt 2.57
445647 AV654627 Hε.271808 Hs.271808:Homo sapienε cDNA FU38018 fiε 2.57
444736 AA533491 Hs.23317 NM_032824:Homo sapiens hypothetical prot 2.57
402861 2.57
450069 AI698139 Hs.202093 Hε.202093:ESTs 2.57
414029 BE297731 Hs.75709 NM_002355:Homo sapfens mannose-6-phospha 2.57
427700 AA262294 Hs.180383 NM_001946:Homo sapiens dual specificity 2.57
449961 AW265634 Hs.133100 Hs.133100:ESTs 2.56
449378 AW664026 Hs.59892 Hs.59882:ESTε, Weakly similar to alpha 5 2.56
442599 AF078037 Hs.324051 (locuslink)NM_006663:Homo sapiens RelA-a 2.56
448633 AA311426 Hs.21635 NM_001070:Homo sapiens tubulin, gamma 1 2.56
416078 AL034349 Hs.79005 NM_002844:Homo sapiens protein tyrosine 2.56
428044 AA093322 Hε.301404 NM_006743:Homo sapienε RNA binding motif 2.56
451564 AU076698 Hs.132760 (l∞usliπk)NM_001467:Homo sapiens glucos 2.56
457601 AF041429 Hs.284265 (tocuslink)NM_145169:Homo sapiens simila 2.56
439630 AA313607 Hs.58633 Hs.58633:Homo sapfens cDNA: FLJ22145 fis 2.55
419587 S62907 Hs.91343 NM_000807:Homo sapienε gamma-aminobutyri 2.55
448279 BE250564 Hs.283655 Hs.283655:lysophospholipase II 2.55
453350 AI917771 Hε.61790 (l∞uslink)NM_024658:Homo sapiens import 2.55
423720 AL044191 Hs.23388 NM_030817:Homo sapiens hypothetical prot 2.55
400237 Hs.83347 NM_001087:Homo sapfens angio-ass∞iated, 2.55
420856 BE513294 Hs.205736 Hs.205736:KIAA1978 protein 2.55
421541 NM.003942 Hs.105584 Hs.105584:ribosomal protein S6 kinase, 9 2.55
434848 BE256304 Hs.32148 NM_018445:Homo sapiens AD-015 protein (L 2.55
424488 AK000413 Hε.148227 (lxuslink)NM_O17806:Homo sapiens hypoth 2.55
449089 D78850 Hs.250465 Hs.250465:Homo εapfens mRNA; cDNA DKFZp4 2.55
430053 AF052155 Hs.227949 NM_030673:Homo sapienε SEC13-like 1 (S. 2.55
437469 AW753112 Hs.15514 Hs.15514:hypothetical protein MGC3260 2.55
407755 AI151353 Hs.29742 Hs.29742:Homo εapiens cDNA FU32147 fis, 2.55
446673 NM 016361 Hs.15871 NM.016361:Homo εapiens LPAP for lysophos 2.55
411766 AA399671 Hs.7igeg Hs.7196g:Homo εapiens mRNA; cDNA DKFZp66 2.55
415198 AW009480 Hs.943 Hs.g43:natural killer cell transcript 4 2.55
436495 BE258948 Hs.290874 Hs.2g0874:Homo sapiens, clone MGC:31984 2.55 417785 X59812 Hs 82568 NM.000784 Homo sapiens cytochrome P450 255
443358 H65417 Hs 17757 (l∞uslιnk)NM_021622 Homo sapiens ptecks 255
452349 AB028044 Hs 29189 Hs 29189 ATPase, Class VI, type 11A 255
427721 AI582843 Hs 180455 NM.005053 Homo sapiens RAD23 homolog A ( 254
407550 AA313352 Hs 280858 Hs 280858 Homo sapiens cDNA FU32370 fis 254
413426 U88837 Hs 75354 Hs 75354 GCN1 general control of amino-a 254
425465 L18964 Hs 1904 Hs 1904 protein kinase C, iota 254
444152 AI125694 Hs 149305 Hs 149305 hypothetical protein MGC2603 254
451820 AW058357 Hs 199248 NM.000958 Homo sapiens prostaglandin E r 254
441356 BE384361 Hs 182885 (locuslιnk)NM_004556 Homo sapiens nuclea 254
444410 BE387360 Hs 33719 Hs 33719 Homo sapiens, similar to data s 254
415200 AL040328 Hs 78202 NM.003072 Homo sapienε SWI/SNF related, 254
403955 254
430361 AI033965 Hs 239g26 Hs 239926 sterol C4-methyl oxidase-like 254
432401 NM.013330 Hs 274479 NM.013330 Homo sapiens NME7 (NME7), mRNA 254
446719 W39500 Hs 301872 Hs 301872 hypothetical protein MGC4840 254
439941 AI392640 Hs 18272 NM.030674 Homo sapiens solute earner fa 254
436685 W28661 Hs 5288 Hs 5288 Homo sapiens mRNA cDNA DKFZp434 254
424522 AL134847 Hs 149957 Hs 149957 nbosomal protein S6 kinase, 9 254
442904 AW575008 Hs 11355 Hs 11355 thymopoietm 254
422605 H16646 Hs 118666 Hs 118666 hypothetical protein PP591 254
442069 AW664144 Hs 297007 Hs 297007 Homo sapiens cDNA FU32174 fis 254
447362 AW176120 Hs 9061 NM.024099 Homo sapiens hypothetical prot 253
416305 AU076628 Hε 79187 NM.001338 Homo sapiens coxsxkie virus a 253
422624 BE616678 Hs 76152 NM.006854 Homo sapienε KDEL (Lys-Asp-Glu 253
447298 BE617527 Hs 239818 NM.006219 Homo sapiens phosphoinositide 253
412833 AW960547 Hs 298262 Hs 298262 πbosomal protein S19 253
404854 253
415761 AA132666 Hs 78802 (l∞uslιnk)NM_002093 Homo sapiens glycog 253
431104 AW970858 Hs 313503 Hs 313503 ESTε 253
439180 AI393742 Hs 199067 Hs 199067 v-erb-b2 erythroblastic leukem 253
424250 AF073310 Hs 143648 NM.003749 Homo sapiens insulin rxeptor 253
452878 AW081128 Hs 246374 Hs 246374 Homo εapiens cDNA FU31250 fis 253
415742 BE410243 Hs 78769 NM.003249 Homo sapiens thimet oligopepti 253
404140 253
407255 AA012992 Hs 256301 Hs 256301 hypothetical protein MGC13170 253
422509 AA258513 Hs 117865 Hs 117865 solute earner family 17 (amo 253
434866 AW002565 Hs 355460 Hs 355460 Homo sapiens cDNA FU21763 fi 253
429743 AA804398 Hs 288995 (tocuslιπk)NM_017961 Homo sapiens hypoth 253
433047 M86135 Hs 279946 NM.004990 Homo sapiens melhionme-tRNA s 253
418945 BE246762 Hs 894gg Hs 89499 arxhidonate 5-lιpoxygenase 252
445926 AF054284 Hs 334826 NM.012433 Homo sapiens splicing fxtor 3 252
411353 BE383533 Hs 279784 Hs 279784 prolxt regulatory element b 252
448252 BE622701 Hs 12199 NM.030577 Homo sapiens hypothetical prot 252
447365 BE383676 Hs 334 (locuslιnk)NM_005435 Homo sapiens Rho gu 252
414844 AA296874 Hs 77494 NM.080916 Homo sapiens deoxyguanosme ki 252
444025 AA578364 Hs 349093 NM.015945 Homo sapiens ovanan cancer ov 252
416149 AA311965 Hs 79058 NM.003168 Homo sapiens εuppressor of Ty 252
418741 H83265 Hs 8881 Hs 8881 Homo sapienε cDNA FU32163 fis, 252
437952 D63209 Hs 5944 NM.014585 Homo sapienε solute earner fa 252
445625 BE246743 Hε 353181 (lxuslmk)NM_025092 Homo sapiens hypoth 252
431565 AF161470 Hs 260622 Hs 260622 butyrate-induced transcπpt 1 252
410179 W27723 Hs 59498 (tocuslιnk)NM_003718 Homo sapiens cell d 252
431476 BE612705 Hs 256697 (lxuslmk)NM_005340 Homo sapienε histid 252
406672 M26041 Hs 198253 (tocuslιnk)NM_002122 Homo sapiens major 252
418180 BE618087 Hs 83724 Hs 83724 hypothetical protein MGC5466 252
428248 AI126772 Hs 40479 Hε 40479 Homo sapiens cDNA FU25802 fis, 252
419935 AB020980 Hs 93832 Hs 93832 putative membrane protein 252
446143 BE245342 Hs 306079 NM.013336 Homo sapiens protein transport 252
426691 NM 006201 Hs 171834 (lxuslιnk)NM_006201 Homo sapiens PCTAIR 251
408124 U89337 Hs 42853 NM.004381 Homo sapienε cAMP responsive e 251
456266 L29073 Hs 198726 NM 003651 Homo sapiens cold εh∞k domain 251
428921 Z43809 Hs 194638 Hs 194638 polymerase (RNA) II (DNA direc 2.51
414721 X90392 Hs 77091 NM.006730 Homo εapienε deoxyπbonuclease 251
422607 Z45471 Hs 118684 NM.006923 Homo sapiens stromal cell-den 251
421846 AA017707 Hs 1432 NM.002743 Homo sapiens protein kinase C 251
414874 D26351 Hs 77515 NM.002224 Homo sapiens inositol 1,4,5-tr 251
432956 AL037895 Hε 279861 NM.015959 Homo sapiens CGI 31 protein (L 251
438393 AA351815 Hs 50740 Hs 50740 Homo sapienε mRNA, cDNA DKFZp76 251
418360 AW296974 , Hs 84264 NM.006401 Homo sapienε xidic (leuoine-r 250
401061 250
426558 AB001914 Hs 170414 Hs 170414 paired basic ammo xid cleavi 250
412204 AH 25507 Hs 24937 Hs 24937 traπsformer-2 alpha (htra-2 alp 250
448950 AF288687 Hs 9275 NM.020410 Homo sapiens CG1 152 protein ( 250
409936 AK001691 Hs 57655 (lxuslmk)NM_018234 Homo sapiens duduli 250
414675 R79015 Hs 288968 Hs 288968 RAB22A, member RAS oncogene fa 250
409983 D50922 Hs 57729 (lxuslιnk)NM_01228g Homo sapiens Kelch 250
450914 AI743761 Hs 142528 Hs 142528 ESTs 250
444630 AI753230 Hs 323562 (tocuslιnk)NM_032121 Homo sapiens hypoth 250
401353 250
441680 AW444598 Hs 7940 (tocuslιnk)NM_021159 Homo εapieπs RAP1, 250
406860 AA876469 AA876469 oe48b04 s1 NCI_CGAP_Pr25 Homo s 250
449163 I AW161356 Hs 23119 NM.003492 Homo sapiens chromosome X open 250 432975 AA331517 Hε 286055 Hs 286055 chimeπn (chimaeπn) 2 250
430600 AW950967 Hε 274348 NM 004639 Homo εapienε HLA B ass∞iated 250
407584 W25845 Hs 8173 Hs 8173 hypothetical protein FLJ10803 250
TABLE 9B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accesεion numbers
Pkey CAT Number Accesεion
406685 0.0 M18728
452098 161393 1 BG028348 BF772844 H83066 AW817969 H90985 BF755039 AI858183
451128 1495511 1 BE072881 AI762181 BE072946
459306 223120 -4 AW578452
448489 2189115 1 R45782 R45781
418869 12789 14 AA229762AA230035
418546 242836 1 T59708 AA224827 T59843 BE156903
455303 1152492 1 BE066801 BE066895 AW882049 BE066897 BE903884
406860 0 0 AA876469
TABLE 9C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
N position Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
406399 9256288 Minus 63448-63554
403220 7630969 Plus 64338-64517
403218 7630969 Plus 58039-58149
403221 7630969 Plus 66294-66438,66936-67124
403219 7630969 Plus 61858-61995
403739 7630882 Plus 44563-44766,48209-48483,52255-52495
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
405556 1552511 Plus 163497-163623,164715-164968,165369-16550
400529 9796988 Plus 138232-138423
404826 6572184 Plus 47726-48046
400750 8119067 Plus 198981-199168,199316-199548
400847 9188605 Plus 44643-44835
400448 9887687 Minus 177372-177674
402829 8918414 Plus 101532-101852,102006-102263
400846 9188605 Plus 39310-39474
401179 9438647 Plus 113477-113893
404240 5002624 Minus 116132-116407,116653-116922
402260 3399665 Minus 113765-113910,115653-115765,116808-11694
406363 9256114 Plus 14403-14602,17000-17147,17241-17368
405203 7230116 Plus 125295-125463
402104 8119072 Plus 122409-122600
403912 7710730 Minus 72000-72290,72431-72700,72929-73199
400845 9188605 Plus 34428-34612
403217 7630969 Pluε 54089-54163,55427-55623
403483 9966188 M uε 144546-144854
400509 9796539 Minus 157909-158430
403399 6684178 Plus 61841-62145,62367-62756
400541 7574902 Plus 126235-126380,126478-126597
402861 2814366 Minus 14933-15231,15387-15627
403955 7770475 Minus 54527-54740
404854 7143420 Plus 14260-14537
404140 9843520 Plus 37761-38147
401061 3242744 Minus 99468-99549,100707-100848,100918-101107,
401353 9931296 Minus 50831-51352
Table 10A lists about 1,103 genes up-regulated in colon cancer compared to normal adult tissues excluding non-malignant colon tisεueε (whole colon and colon epithelium) These were selxted from the starting collxtion of 59680 probesets on the Affymetπx/Eos-Hu03 GeneChip® array aε followε the ratio of "average" colon to "average" nomial adult tiεεues was greater than or equal to 25, the "average" colon level was set to the 90th percentile value amongst colon pπmary cancer spximens and colon liver deπved metatases, the "average" normal adult tissue level was set to the 85th percentile value amongst non malignant tisεues minus the colonio denved samples, the "average" colon value was greater than or equal to 50 units In order to remove gene-εpxific bxkground levels of non spxific hybndization, the 15th percentile value amongst the over non malignant tisεues was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 10A 1 ,103 genes up-regulated in colon cancer compared to normal adult tissues excluding non malignant colon tissues (whole colon and colon epithelium)
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of tumor to normal adult tissues Pkey ExAccn UnigenelD Unigene Title R1
436749 AA584890 Hs.5302 NM_006149:Homo sapiens lectin, galxtosi 15.54
428934 AF039401 Hs.194659 NM_001285:Homo sapiens chloride channel, 14.52
446787 U67167 Hs.315 NM_002457:Homo sapienε mucin 2, intestin 14.04
431912 AI660552 Hs.356183 Hs.356183:ESTs, Weakly εimilar to S3B4.H 14.02
423541 AA296922 Hs.12g778 NM.014471:Homo sapiens serine proteasei 13.72
406690 M29540 Hs.220520 (l∞uslink)NM_004363:Homo sapienε carcin 13.44
418406 X73501 Hs.84905 Hs.84905:cytokeratin 20 12.70
406667 Ml 2523 12.42
416768 AA363733 Hs.1032 NM_006507:Homo sapiens regenerating isle 11.98
437835 AW939591 Hs.5940 NM_033049:Homo sapienε mucin 13, epithel 11.58
422578 AF239666 Hs.1545 NM_001804:Homo εapiens caudal type homx 11.50
418888 AU076801 Hs.89436 NM_004063:Homo sapfens cadherin 17, LI c 10.16
418007 M13509 Hs.83169 NM_002421:Homo sapiens matrix metallopro 10.11
422260 AA315993 Hs.105484 NM_032044:Homo sapiens regenerating gene 10.01
421582 AI910275 Hs.350470 NM_003225:Homo sapiens trefoil fxtor 1 9.77
441031 AH 10684 Hs.7645 NM_005141:Homo sapienε fibrinogen, B bet 9.69
424212 NM 05814 Hs.143131 NM_005814:Homo sapiens glycoprotein A33 9.48
453863 X02544 Hs.572 Hs.572:oroεomucoid 1 9.20
407243 AA058357 Hs.74466 (lxuslink)NM_006890:Homo sapiens carcin 9.18
436217 T53925 Hs.107 NM_004467:Homo sapiens fibrinogeπ-like 1 9.04
423371 AU076819 Hs.1650 NM.000111 :Homo sapienε solute carrier fa 8.69
430178 AW449612 Hs.152475 Hs.152475:ESTs 8.51
423673 BE003054 Hs.1695 NM_002426:Homo sapiens matrix metallopro 8.43
447400 AK000322 Hs.18457 NM_017763:Homo sapiens hypothetical prat 8.17
408683 U33317 Hs.711 NM_001926:Homo sapfens defensin, alpha 6 8.12
431777 AA570296 Hε.307047 NM_032579:Homo sapiens colon and small i
450685 L15533 Hs.423 NM_138938:Homo sapiens pancreatitis-asso 8.06
427583 M82962 Hs.179704 NM_005588:Homo sapienε eprin A, alpha ( 7.95
436624 T64297 Hs.351719 NM_001443:Homo sapiens fatty xid bindin 7.74
410407 X66839 Hs.63287 NM_001216:Homo sapiens carbonic aπhydras 7.46
413719 BE439580 Hs.75498 NM_004591:Homo sapienε εmall inducible c 7.41
407007 U22961 Hε.184411 NM_000477:Homo sapiens albumin (ALB), mR 7.40
412374 X01388 Hs.73849 NM_000040:Homo sapiens apolipoprotein C- 7.34
407244 M10014 7.31
419741 NM.007019 Hs.93002 Hs.93002:ubiquitin-conjugating enzyme E2 7.31
406741 AA058357 Hs.74466 (lxuslink)NM_006890:Homo sapienε carcin 7.26
414386 X00442 Hs.75990 NM_005143:Homo εapfens haptoglobin (HP), 7.21
404519 7.18
413585 AI133452 Hs.75431 ' NM_000500:Homo sapiens fibrinogen, gamma 7.13
422281 M36803 Hs.346935 NM_000613:Homo sapfens hemopexin (HPX), 7.10
414463 T69078 Hs.76177 NM.001633:Homo sapiens alpha-1-microglob 7.02
430828 AI763257 Hs.86327 Hs.86327:homeo box B8 6.83
433927 AI557019 Hs.116467 NM_032391:Homo sapiens small nuclear pro 6.81
406687 M31126 Hs.352054 Hs.352054:pregnancy spxific beta-1-glyc 6.78
423538 AW603823 Hs.146268 Hs.146268:ESTs, Weakly similar to C71400 6.53
434206 AW136973 Hs.362915 Hε.362915:Homo sapiens cDNA FU34876 fis 6.37
409041 AB033025 Hs.50081 Hs.50081:KIAA1199 protein 6.33
432542 AW083920 Hs.16008 NM_020384:Homo sapiens claudin 2 (CLDN2) 6.19
422664 AA315933 Hs.120879 Hs.120879:Homo εapienε, clone MGC32871 6.19
436330 NM.004413 Hε.109 NM_004413:Homo εapienε dipeptidaεe 1 (re 6.01
421964 X73079 Hs.28857g NM_002644:Homo sapiens polymeric immunog 6.00
430272 X04898 Hs.237658 Hs.237658:apolipoprotein A-ll 5.97
413881 L00190 Hs.75599 (tocuslink)NM_000488:Homo sapiens serine 5.94
420923 AF097021 Hs.273321 NM_006418:Homo sapienε differentially ex 5.94
428470 AC002301 Hs.184507 Hs.184507:Homo sapiens, similar to Homol 5.90
420802 U22376 Hs.1334 NM_005375:Homo sapiens v-myb myeloblasto 5.89
452304 AA025386 Hs.61311 Hs.61311:ESTs, Weakly similar to S10590 5.89
431727 AW293464 Hs.162031 Hs.162031:ESTs 5.85
421341 AJ243212 Hs.374281 NM_007320:Homo sapiens deleted in malign 5.84
432023 AW273128 Hs.300268 Hs.300268:EST 5.75
447033 AI357412 Hε.157601 Hs.157601:ESTs 5.69
411734 AW374954 Hs.71779 Hs.7177ftESTs, Weakly similarto S24C.AR 5.69
406685 M18728 (tocuslink)NM_002483:Homo sapiens carcin 5.55
428753 AW939252 Hs.192927 NM_017726:Homo sapienε protein phoεphata 5.48
443247 BE614387 Hs.3338g3 Hs.333893:cell division cycle ass∞iated 5.45
409153 W03754 Hs.50813 NM.017625:Homo εapienε intelxtin (ITLN) 5.44
449388 H53191 Hs.36723 Hs.36723:ESTs, Weakly εimilar to C05G5.5 5.38
428046 AW812795 Hs.337534 Hε.337534:Homo εapieπs cDNA FU25241 fis 5.38
433013 AI697890 Hs.127337 (locuslink)NM 004655:Homo sapiens axin 2 5.38
419079 AW014836 Hε.18844 Hs.18844:ESTs 5.37
428355 BE256452 Hs.2257 NM_000638:Homo εapiens vitroπxtin (seru 5.35
422956 BE545072 Hs.122579 (l∞uslink)NM_018098:Homo εapienε epithe 5.34
424326 NM 014479 Hs.145296 NM.014470:Homo εapiens ADAM-like, dxysi 5.30
450543 AI394037 Hε.170296 Hs.170296:Homo sapiens cDNA: FU22090 fi 5.30
428187 AI687303 Hs.285529 Hs.285529:G protein-coupled receptor 49 5.30
435538 AB011540 Hs.4930 Hs.4930:low density lipoprotein rxeptor 5.28
411825 AK000334 Hs.352415 NM.017767:Homo sapiens solute carrier fa 5.28
427722 AK000123 Hs.180479 NM_017671:Homo sapiens chromosome 20 ope 5.26
430569 AF241254 Hs.178098 NM_021804:Homo sapienε angiotenεin I con 5.26
414816 Y13709 Hs.77399 NM_001265:Homo εapiens caudal type homx 5.21
430677 Z26317 Hs.359784 NM_001943:Homo sapfens desmoglein 2 (DSG 5.16 447208 BE315291 Hs.237971 NM 024096:Homo sapiens hypothetical prot 5.14
430207 AW079559 Hs.152258 Hs.Ϊ52258:ESTs 5.12
417401 AW376842 Hs.1085 NM_004963:Homo sapiens guanylate cyclase 5.12
421379 Y15221 Hs.103982 NM_005409:Homo sapfens small inducible c 5.07
447342 AI199268 Hs.19322 Hs.ig322:Homo εapienε, Similar to RIKEN 5.06
452194 AI694413 Hs.373599 Hs.373599:EST 5.01
421907 BE018556 Hs.109358 Hs.109358:ATPase, Class V, type 10B 4.99
406399 4.98
403220 4.94
408380 AF123050 Hs.44532 NM 006398:Homo sapiens ubiquitin D (UBD) 4.92
415214 AI445236 Hs.125124 NM_004442:Homo sapfens EphB2 (EPHB2), tr 4.92
431330 X69532 Hs.2777 NM_002215:Homo sapiens inter-alpha (glob 4.85
420344 BE463721 Hs.97101 NM_014373:Homo sapiens putative G protei 4.84
452594 AU076405 Hs.29981 Hs.29981:εolute earner family 26 (sulfa 4.81
441377 BE218239 Hs.202656 Hs.202656:ESTs 4.81
444666 BE293347 Hs.11638 (l∞usliπk)NM_016234:Homo sapiens fatty- 4.80
415701 NM 003878 Hs.78619 (lxuεlink)NM_003878:Homo sapiens gamma- 4.80
419354 M62839 Hs.1252 NM_000042:Homo sapiens apolipoprotein H 4.80
455630 AV655701 Hs.75183 NM_000773:Homo sapiens cytxhrome P450, 4.78
422310 AA316622 Hs.98370 (lxuslink)NM_030622:Homo sapiens cyt∞h 4.78
423337 NM 004655 Hε.127337 NM_004655:Homo sapfens axin 2 (condu in 4.75
422330 D30783 Hs.115263 NM_001432:Homo sapiens epiregulin (EREG) 4.73
408908 BE296227 Hs.250822 (lxuslink)NM_003158:Homo sapiens serine 4.70
423936 U77629 Hs.135639 NM_005170:Homo sapfens xhaete-scute com 4.70
404661 4.68
408704 AA056635 Hs.5366 NM 139053:Homo sapfens epidermal growth 4.67
420005 AW271106 Hs.133294 Hs.133204:EST8 4.66
451035 AU076785 Hs.430 NM_002670:Homo sapiens plastin 1 (I isof 4.61
427506 AK000134 Hs.179100 NM_017678:Homo sapiens hypothetical prot 4.60
423445 NM 014324 Hs.128749 NM.014324:Homo sapiens alpha-methylxyl- 4.59
453884 AA355925 Hε.36232 NM_021067:Homo sapiens KIAA0186 gene pro 4.55
431301 AA502384 Hs.151529 Hs.151528:ESTs 4.54
408983 NM 000492 Hs.663 NM_000492:Homo sapfens cystic fibrosis t 4.54
449032 AA045573 Hs.22900 NM_004289:Homo sapfens nuclear fxtor (e 4.54
434540 NM 016045 Hs.3945 NM.016045:Homo sapiens chromosome 20 ope 4.54
407242 M18728 (tocuslink)NM_002483:Homo sapiens carcin 4.53
458748 A1381530 Hs.371132 Hs.371132:ESTs 4.53
408298 AI745325 Hs.271923 Hs.271923:Homo sapiens cDNA: FU22785 fi 4.51
424273 W40460 Hs.144442 NM_003561:Homo sapiens phospholipase A2, 4.50
411975 AI916058 Hs.144583 Hs.144583:Homo sapienε, clone IMAGE:3462 4.49
425371 D49441 Hs.155981 NM_005823:Homo sapiens meεolhelin (MSLN) 4.49
451917 AW391351 Hs.50820 Hs.50820:hypothetical cardix/skeletal m " 4.46
432867 AW016936 Hs.233364 Hs.233364:ESTs 4.44
419559 Y07828 Hs.91096 NM_007028:Homo sapiens tripartite motif- 4.44
430294 AI538226 Hs.32976 (tocuslink)NM_004485:Homo sapiens guanin 4.42
411248 AA551538 Hs.69321 Hs.69321:KIAA1359 protein 4.39
402496 4.38
430937 X53463 Hs.2704 NM_002083:Homo sapienε glutathione perox 4.37
434414 AI798376 AF134163:Homo sapiens Human endogenous r 4.36
443426 AF098158 Hs.9329 (tocuslink)NM_012112:Homo sapiens chromo 4.35
422539 AJ009g36 Hs.118138 NM_033013:Homo sapiens nuclear receptor 4.33
436972 AA284679 Hε.25640 Hε.25640:claudiπ 3 4.33
450531 AW301032 Hs.203800 Hε.203800:ESTε 4.33
403055 4.31
414809 A1434699 Hs.77356 Hs.77356:transferrin rxeptor (p90, CD71 4.31
400965 4.30
430204 AA618335 Hs.356664 Hε.356664:hypothetical protein FU32334 4.29
432978 AF126743 Hs.279884 NM_013238:Homo sapiens DNAJ domain-eonta 4.29
417931 Wg5642 Hs.82961 Hs.82961:Homo sapfens, clone MGC:225881 4.28
430832 AI073913 Hs.100686 Hs.100686:aπterior gradient protein 3 4.28
408482 NM 000676 i Hs.45743 NM_000676:Homo sapiens adenosine A2b rx 4.28
422487 AJ010901 Hs.198267 NM.018406:Homo sapiens mucin 4, trxheob 4.27
414617 AI339520 Hs.288817 (lxuslink)NM_025130:Homo sapiens hypoth 4.27
452940 AA029722 Hs.2173 NM_002033:Homo sapiens fucosyltransferas 4.27
439211 AI890347 Hs.271923 Hs.271923:Homo sapiens cDNA: FU22785 fi 4.27
459299 BE094291 Hs.155651 NM_021784:Homo sapiens hepatxyte nuclea 4.25
449720 AA311152 Hs.288708 (tocuslink)NM_025113:Homo sapienε hypoth 4.24
411142 NM 014256 Hs.6900g NM_014256:Homo εapieπs UDP-GlcNAo:betaGa 4.24
421777 BE562088 Hs.108196 NM.016095:Homo sapiens HSPC037 protein ( 4.21
419395 BE268326 Hs.90280 Hs.90280:5-amiπoimidazole-4-carboxamide 4.20
443211 AM 28388 Hε.143655 Hs.143655:ESTs 4.20
403218 4.20
430603 AA148164 Hε.247280 Hε.247280:chromosome 20 open reading fra 4.19
409757 NM.001898 Hs.123114 NM_001898:Homo sapiens cystatin SN (CST1 4.19
426227 U67058 Hs.154299 (l∞uslink)NM_005242:Homo sapiens coagul 4.19
421408 AI688223 Hs.91096 NM_052816:Homo sapiens tripartite motif- 4.18
421100 AW351839 Hs.124660 Hs.124660:ESTs, Moderately εimilar to 21 4.18
440869 NM 014297 Hs.7486 NM.014207:Homo sapiens protein expressed 4.17
414075 U11862 Hs.75741 NM_0010gi:Homo sapienε amiloride binding 4.17
444151 AW972917 Hs.128749 (tocuslink)NM_014324:Homo sapiens alpha- 4.16
440409 AW2g4316 Hs.125608 Hs.125608:ESTs 4.16
445564 AB028957 Hs.12896 Hs.12896:KIAA1034 protein 4.16
424687 J05070 Hs.151738 NM_004994:Homo sapiens matrix metallopro 4.12 401866 4 11
431611 U58766 Hs264428 Hs 264428 tissue spxific transplantatio 4 10
430187 AI799909 Hs 158989 Hs 158989 Homo sapiens cDNA FU37936 fis 4 10
414590 NM 000506 Hs 76530 NM.000506 Homo εapiens coagulation fxto 408
449281 AI808699 Hs 162717 NM.032756 Homo sapiens hypothetical prot 408
449722 BE280074 Hs 23960 Hs 23960 cyclin B1 408
418318 U47732 Hs84072 NM.004616 Homo sapiens tranεmembrane 4 s 406
435066 BE261750 Hs4747 NM.001363 Homo sapiens dyskeratosis cong 405
414753 AF158255 Hε77225 NM 006437 Homo sapiens ADP πbosyltransf 404
403221 404
409889 AW630041 Hs 56937 NM.021978 Homo sapiens suppression of tu 403
449027 AJ271216 Hs 22880 NM.005700 Homo sapiens dipeptidylpeptida 403
431657 AI345227 Hs 105448 Hs 105448 protein kinase, lysine deficie 401
439759 AL358055 Hs 67709 Hs 67709 Homo sapiens mRNA full length I 400
441362 BE614410 Hs 23044 NM.080668 Homo sapiens similar to RIKEN 399
417900 BE250127 Hs 82906 Hs 82906 CDC20 cell division cycle 20 ho 39g
428987 NM 004751 Hs 194710 NM.004751 Homo sapiens glucosaminyl (N-a 3 09
456977 AK000252 Hs 169758 NM.017723 Homo sapiens hypothetical prot 39g
445919 T53519 Hs 334692 Hs 334692 hypothetical protein MGC14141 398
423164 AK000232 Hs 124835 NM.019062 Homo sapiens hypothetical prot 398
422627 BE336857 Hs 118787 Hs 118787 transforming growth fxtor, be 397
422363 T55079 Hs 115474 NM.002915 Homo sapiens replication fxto 397
433437 U20536 Hs3280 NM.001226 Homo sapiens caspase 6, apopto 397
415992 C05837 Hε 145807 Hε 145807 hypothetical protein FU13593 3 6
425834 NM 001639 Hε 1957 Hs 1957 amyloid P component, serum 396
415000 AW025529 Hs239812 Hs 239812 serologically defined breast c 385
432407 AA221036 AF134164 Homo sapiens Human endogenous r 3 g5
408243 Y00787 Hs624 NM.000584 Homo sapiens interleukin 8 (IL 3 g4
408494 AA554714 Hs 187578 Hs 187578 Homo sapienε cDNA FU11639 (is 394
412610 X90908 Hs 74126 NM.001445 Homo sapiens fatty xid bindin 394
433323 AA805132 Hs 159142 Hs 159142 lunatic fringe homolog (Drosop 394
422515 AW500470 Hs 117950 Hs 117950 phosphoπbosylaminoimidazole c 392
436543 NM 002212 Hs5215 Hs 5215 integπn beta 4 binding protein 391
418113 AI272141 Hs 83484 Hs 83484 SRY (sex determining region Y)- 391
433083 AL042759 Hs 191762 Hs 191762 hypothetical protein MGC20258 390
431939 AW008061 Hs 231994 Hs 231094 Homo sapienε clone IMAGE 4341 3 go
453439 AI572438 Hs 32976 NM.004485 Homo sapiens guanine nucleotid 389
441888 AI733306 Hs 128071 NM.022901 Homo sapiens hypothetical prot 389
432150 AK000224 Hs 272789 NM.017716 Homo sapiens membrane-spanning 389
425234 AW152225 Hε 165909 Hs 165909 ESTs, Weakly similar to hypoth 389
423803 NM 005709 Hs 132945 (l∞uslmk)NM_005709 Homo sapiens PDZ-73 387
410418 D31382 Hs 63325 NM.019894 Homo sapiens transmembrane pro 385
436251 BE515065 Hs 296585 (lxuslιnk)NM_006392 Homo sapiens nucl∞ 385
422424 AI186431 Hs 296638 Hs 296638 prostate differentiation fxto 384
432269 NM 002447 Hs2942 Hs 2942 mxrophage stimulating 1 rxepto 384
424905 NM 002497 Hs 153704 NM.002497 Homo sapiens NIMA (never in mi 384
416209 AA236776 Hs70078 NM 002358 Homo sapienε MAD2 mitotic arre 383
430680 AW138724 Hs 168974 Hs 168974 ESTs 383
434370 AF130988 Hs 58346 NM.022336 Homo sapiens xtodysplasiπ 1, 382
436481 AA379597 Hs5199 NMJ14176 Homo sapiens HSPC150 protein s 382
453700 AB009426 Hs560 NM.001644 Homo sapiens apolipoprotein B 381
410619 BE512730 Hε65114 Hs 65114 keratin 18 381
409420 Z15008 Hs 54451 NM.0O5562 Homo sapienε laminin, gamma 2 379
422535 AA311914 Hs 154578 Hε 154578 Homo sapiens mRNA for FU00256 379
432179 X75208 Hs2913 NM.004443 Homo sapiens EphB3 (EPHB3) mR 378
453967 AW000077 Hs 232947 Hs 232947 ESTs 378
426106 AI678765 Hs 21812 Hs 21812 ESTs 378
434170 AA626500 Hs 159642 (lxuslιnk)NM_001490 Homo sapienε glucos 378
418322 AA284166 Hs 84113 NM.005192 Homo sapiens cyclm-dependent 378
444381 BE387335 Hs 283713 NM 138455 Homo sapienε collagen triple h 374
419229 AI827237 Hs 362919 Hε 3629i ESTε 374
437156 AI916600 Hs 121194 Hε 121194 Homo εapiens cDNA FU21569 fi 374
452833 BE559681 Hs 30736 (l∞uslιnk)NM_015201 Homo εapiens block 373
426831 BE296216 Hs 172673 NM.000687 Homo sapienε S adenoεylhom∞ys 373
428970 BE276891 Hs 194691 NM.003979 Homo sapiens retinoic xid ind 372
443957 AA521049 Hs 353013 Hs 353013 chromosome 20 open reading fra 371
408832 AW085690 Hs 63428 Hs 63428 Homo sapiens cDNA FU34457 fis, 371
440300 N39760 Hs8859 NM.138793 Homo sapiens apyrase (SHAPY), 371
425976 C75094 Hs 334514 NM.025257 Homo sapiens chromosome 6 open 371
432575 AA553722 Hs 194346 Hs 194346 Spιr-2 protein 371
412104 AW205197 Hs 240951 (tocuslιnk)NM_033120 Homo εapienε naked 371
417001 AU076648 Hs 80741 NM.000282 Homo sapiens propionyl Coenzym 369
421225 AA463798 Hs 102696 Hs 102696 MCT-1 protein 369
445109 AF039916 Hs 12330 NM.001247 Homo sapiens xtonucteoside tr 369
428330 L22524 Hs2256 NM.002423 Homo εapiens matrix metallopro 367
447472 AW207347 Hs 211101 Hs 211101 ESTs 367
423349 AF010258 Hs 127428 NM.002142 Homo sapiens homx box A9 (HOX 367
422026 U80736 Hs 110826 Hs 110826 tπnucleotide repeat containin 366
419574 AK001989 Hs 91165 Hs 91165 hypothetical protein FU11127 366
417720 AA205625 Hs 208067 Hs 208067 ESTs 366
411257 AA628967 Hs 115274 Hs 115274 Indian hedgehog homolog (Droso 366
421515 Y11339 Hs 105352 (tocuslιnk)NM_018414 Homo sapienε GalNAc 365
433675 AW977653 Hs 75319 Hε 75319 πbonucleotide reductase M2 pol 365 437008 AF127026 Hs.5304 NM_005379:Homo sapiens myosin IA (MY01A) 3.65
445417 AK001058 Hs.12680 Hs.Ϊ2680:Homo sapfens cDNA FU10196 fis, 3.64
412140 AA219691 Hs.73625 NM_005733:Homo sapfens RAB6 interacting, 3.64
420542 NM 000505 Hs.1321 NM_000505:Homo sapfens coagulation fxto 3.63
439453 BE264074 Hs.6566 Hs.6566:thyroid hormone rxeptor interac 3.63
414798 AI286323 Hs.97411 Hs.g7411:hypothetical protein MGC12335 3.62
428862 NM 000346 Hs.2316 Hs.2316:SRY (εex determining region Y)-b 3.62
414052 AW578840 Hs.283552 Hs.283552:hypolhetical protein BC016153 3.62
412056 T28160 Hs.778 Hs.778:guanylate cyclase activator 2A (g 3.61
401519 3.60
428011 BE387514 Hs.181418 NM_014730:Homo sapiens KIAA0152geπe pro 3.60
450505 NM.004572 Hs.25051 NM_004572:Homo sapiens plakophiliπ 2 (PK 3.60
421903 AW079940 Hs.15951 (tocuslink)NM_145202:Homo sapiens proiin 3.58
413936 AF113676 Hs.297681 NM_000295:Homo sapiens serine (or cystei 3.58
424544 M88700 Hs.150403 NM_000790:Homo sapiens dopa dxarboxylas 3.58
431563 AI027643 Hs.120912 Hs.120912:ESTs 3.57
435602 AF217515 Hs.283532 NM 018455:Homo sapiens uncharxterized b 3.57
434369 AI650363 Hs.116462 Hs.116462:ESTs 3.57
439963 AW247529 Hs.6793 Hs.6793:platelet-xtivatiπg fxtor acety 3.56
447334 AA515032 Hs.91109 Hs.91109:ESTs, Weakly εimilar to putativ 3.56
422150 AI867118 Hs.27g607 Hε.279607:Homo sapfens cDNA FU34309 fis 3.56
450663 H43540 Hs.25292 Hs.25292:ribonuclease H2, large subunit 3.56
424825 AF207069 Hs.153357 NM_001084:Homo sapiens pr∞ollagen-lysin 3.56
422765 AW409701 Hs.1578 NM.001168:Homo sapfens bxuloviral IAP r 3.55
422106 D84239 Hs.111732 NM_0038gθ:Homo sapfens IgG Fc binding pr 3.55
422532 AL008726 Hs.118126 (lxuslink)NM_000308:Homo εapiens protx 3.55
425860 L29339 Hs.1964 NM_000343:Homo sapfens solute earner fa 3.55
442053 R35343 Hs.24968 Hs.24968:hypothetical protein BC016683 3.55
437386 W52452 Hs.356766 Hs.356766:Homo sapiens mRNA; cDNA DKFZp7 3.54
415927 AL120168 Hs.78819 NM_021083:Homo sapiens Kell blood group 3.53
446372 AB020644 Hs.14945 Hs.14945:fatty-xid-Coenzyme A ligase, I 3.53
432378 AI493046 Hs.146133 Hs.146133:ESTs 3.53
434171 BE247688 Hs.347349 (locuslink)NM_004749:Homo sapiens cell c 3.52
428479 Y00272 Hs.334562 NM_001786:Homo sapiens cell division eye 3.52
415099 AI492170 Hs.77917 NM_006002:Homo sapiens ubiquitin carboxy 3.51
414018 AI219207 Hs.72222 Hs.72222:fer-1-like 4 (C. elegans) 3.51
440340 AW895503 Hs.125276 Hs.125276:Homo sapiens cDNA FU25833 fis 3.51
418384 AW149266 Hs.25130 Hs.25130:Homo sapiens cDNA FU14923 fis, 3.51
418203 X54942 Hs.83758 NM_001827:Homo sapiens CDC28 protein kin 3.51
429833 NM.012079 Hs.288627 NM.012079:Homo sapiens dixylglycerol O- 3.51
409231 AA446644 Hs.692 NM_002354:Homo sapiens tumor-ass∞iated 3.50
431567 N51357 Hs.260855 (locuslink)NM_145175:Homo sapiens NSE1 ( 3.50
453883 AI638516 Hs.347524 Hs.347524:Homo sapienε, clone MGC:24665 3.50
442700 AA377618 Hs.103834 NM_024056:Homo sapiens hypothetical prot 3.50
410237 AI750589 Hs.61258 Hs.61258:argininosuccinate lyase 3.50
428407 NM 003963 Hs.184194 NM_003963:Homo sapiens transmembrane 4 s 3.49
436213 AA325512 Hs.71472 NM_024662:Homo sapiens hypothetical prot 3.49
442923 AW248322 Hs.95835 3.49
431548 AI834273 Hs.9711 NM_017515:Homo sapiens novel protein (HS 3.48
452316 AA298484 Hs.61265 NM_138805:Homo sapiens family with seque 3.48
448993 AI471630 Hs.355952 Hs.355952:ESTs, Weakly similar to 090320 3.48
447320 AI675419 Hs.164464 Hs.164464:Homo sapiens, clone MGC.-23656 3.48
414108 AI267592 Hs.75761 NM_003137:Homo sapiens SFRS protein kina 3.47
420996 AK001927 Hs.100895 (tocuslink)NM_018099:Homo sapiens hypoth 3.47
439580 AF086401 Hs.293847 Hs.2g3847:ESTs 3.46
422158 L10343 Hs.112341 NM_002638:Homo sapiens protease iπhibito 3.46
418256 AW845318 Hs.12271 (tocuslink)NM_012162:Homo sapiens F-box 3.46
400157 Hs.356473 NM_006713:Homo sapiens xlivated RNA pol 3.46
406709 AI355761 Hs.242463 Hs.242463:keratin 8 3.46
453751 R36762 Hs.101282 Hs.101282:Homo sapiens mRNA; cDNA DKFZp4 3.46
421526 AL080121 Hs.105460 NM_015393:Homo sapiens DKFZP564O0823 pro 3.45
415164 AW084352 Hs.157123 Hs.157123:ESTs 3.45
405451 3.44
414361 AI086138 Hs.204044 Hs.204044:ESTε 3.44
422237 M13149 Hs.1498 NM_000412:Homo sapiens histidine-rich gl 3.44
417576 AA339449 Hs.82285 NM_000819:Homo sapienε phosphoribosylgly 3.44
457001 J03258 Hs.2062 Hε.2062:vitamin D (1 ,25- dihydroxyvitami 3.43
450983 AA305384 Hs.25740 NM_014584:Homo sapiens EROUike (S. cer 3.43
421828 AW891965 Hs.367942 Hs.367942:Homo εapfens, clone IMAGE:4701 3.42
418588 BE387040 Hs.182476 NM_031295:Homo sapiens Williams Beuren s 3.42
417348 AI940507 Hε.318526 NM_025138:Homo sapiens hypothetical prot 3.42
423554 M90516 Hε.1674 NM_002056:Homo sapiens glutamine-fructos 3.42
451310 AW250651 Hs.26213 NM_052951:Homo sapiens chromosome 20 ope 3.41
425873 NM 013390 Hs.160417 Hs.160417:transmembrane protein 2 3.41
429271 AF039850 Hs.198515 NM_005224:Homo sapiens dead ringer-like 3.40
437575 AW954355 Hs.36529 NM_024320:Homo sapiens hypothetical prot 3.40
432677 NM.004482 Hε.278611 NM_004482:Homo sapiens UDP-N-xetyl-alph 3.40
439955 AW203959 Hs.149532 Hs.149532:ESTs 3.40
443991 NM.002250 Hs.10082 NM_002250:Homo sapienε potassium interme 3.40
435745 AW06705g Hε.374342 Hs.374342:Homo sapiens clone 24711 mRNA 3.40
403532 3.39
413916 N49813 Hε.75615 NM_000483:Homo sapiens apolipoprotein C- 3.39
425247 NM.005940 Hs.155324 Hs.155324:matrix metaltoproteinase 11 (s 3.39 424996 AF006005 Hs.154104 NM_002657:Homo sapienε pleiomoφhic aden 3.38
402944 3.37
417165 R80137 Hs.302738 Hε.302738:Homo sapiens cDNA: FU21425 fi 3.37
427528 AU077143 Hs.179565 NM_002388:Homo sapiens MCM3 minichromoso 3.37
426711 AA383471 Hs.343800 (lxuεlink)NM_033255:Homo sapiens epithe 3.37
439186 AI697274 Hε.105435 Hs.105435:GDP-mannose 4,6-dehydratase 3.36
444783 AK001468 Hs.62180 NM.018685:Homo sapiens anillin, xtin bi 3.36
426174 AA547959 Hs.115838 Hs.115838:ESTε 3.36
421585 U95626 Hs.302043 NM_003865:Homo εapiens chemokine (C-C mo 3.36
421605 BE440108 Hs.106127 NM.015972:Homo sapiens RNA polymerase I 3.36
446921 AB012113 Hs.16530 NM_002988:Homo sapiens small inducible c 3.36
438746 AI885815 Hs.184727 Hs.184727:ESTs, Weakly similar to T45738 3.36
403219 3.36
420981 L40904 Hs.100724 NM_005037:Homo sapienε peroxisome prolif 3.34
456946 T29678 Hs.166068 Hs.166068:villin 1 3.33
425580 L11144 Hs.1907 Hs.1807:galanin 3.33
412605 AW410734 Hs.74111 Hs.74111:RNA binding protein (autoantige 3.33
441384 AA447849 Hs.288660 Hε.288660:Homo sapiens cDNA: FLJ22182 fi 3.33
416782 L35035 Hs.79886 (lxuslink)NM_144563:Homo εapiens ribose 3.33
426761 AI015709 Hs.172089 Hs.172089:pro-oπcosis rxeptor inducing 3.33
441633 AW958544 Hs.112242 NM_032413:Homo sapienε normal mucosa of 3.32
416975 NM 004131 Hs.1051 NM_004131:Homo sapiens granzyme B (granz 3.31
428874 W32133 Hs.194366 Hs.194366:traπsthyretjn (prealbumin, amy 3.31
431192 AI670056 Hs.137274 Hs.137274:ESTε, Weakly similar to hypoth 3.30
431836 AF178532 Hs.271411 NM_1389g2:Homo sapiens beta-site APP-cle 3.30
413219 AA878200 Hs.118727 Hs.118727:Homo sapiens cDNA FU33803 fis 3.30
410639 BE269047 Hs.65234 (lxusliπk)NM_0178g5:Homo sapienε DEAD/H 3.29
450737 AW007152 Hs.63325 Hs.63325:transmembrane protease, serine 3.29
410850 AW362867 Hs.302738 Hs.302738:Homo εapiens cDNA: FLJ21425 fi 3.29
428450 NM 014781 Hs.184339 NM_014791:Homo sapienε maternal embryoni 3.29
437810 BE246399 Hs.367646 NM_016617:Homo εapiens hypothetical prat 3.29
403381 3.28
434031 BE384165 Hs.23723 (locuslink)NM_025215:Homo sapienε pseudo 3.28
421975 AW961017 Hs.6459 (Iκuεlink)NM 024531 :Homo sapiens hypoth 3.28
452299 AW206330 Hs.355663 Hs.355663:ESTs 3.28
428024 Z29067 Hs.2236 Hε.2236:NIMA (never in mitosis gene a)-r 3.28
412994 D32257 Hs.75113 Hs.75113:geπeral transcription fxtor II 3.28
443162 T49951 Hs.g020 (lκuslink)NM_015515:Homo sapiens type I 3.28
435327 BE301871 Hs.4867 Hs.4867:maπnosyl (alpha-1 ,3-)-glycoprote 3.28
424010 AL080188 Hs.137556 NM_033100:Homo εapienε MT-prot∞adherin 3.28
428953 AA306610 Hs.348183 NM_003823:Homo sapiens tumor nxrosis fa 3.27
419359 AL043202 Hs.90073 Hs.00073:CSE1 chromosome εegregatioπ 1-1 3.27
414695 BE439915 Hs.76913 Hs.76913:prateasome (proεome, mxropain) 3.27
444371 BE540274 Hs.239 Hε.239:forkhead box M1 3.27
450221 AA328102 Hs.24641 NM.018204:Homo sapiens cytoskeleton aεso 3.27
449207 AL044222 Hs.23255 NM_004298:Homosapienε nudeoporin 155kD 3.27
422609 Z46023 Hs.118721 NM_000434:Homo sapiens sialidase 1 (lyso 3.27
403485 3.27
441623 AA315805 Hs.348710 Hs.348710:Homo εapiens, clone IMAGE4242 3.26
421043 BE616520 Hs.343912 NM_033504:Homo sapienε CAC-1 (CAC-1), R 3.26
405484 3.26
435840 BE305242 Hs.16098 Hε.16098:claudin 2 3.26
449139 BE268315 Hε.23111 NM_004461:Homo εapienε phenylalanine-tRN 3.26
404684 3.25
447188 H65423 Hs.17631 NM_030804:Homo sapiens hypothetical prot 3.25
423226 AA323414 Hs.146109 Hs.146109:ESTs, Weakly similar to T28937 3.24
413254 U40272 Hs.75253 NM_004135:Homo sapienε iε∞itrate dehydr 3.24
424243 AI949359 Hε.143600 Hε.143600:golgi phoεphoprotein 4 3.24
435014 BE560898 Hε.10026 NM_022061:Homo sapiens ribosomal protein 3.24
452281 T93500 Hs.28792 Hs.28792:Homo sapiens cDNA FU11041 fis, 3.24
416065 BE267931 Hs.78996 NM_002592:Homo sapienε proliferating eel 3.23
427333 AF067797 Hs.176658 NM.001169:Homo sapiens aquaporin 8 (AQP8 3.23
443464 BE548446 Hs.321579 NM_021095:Homo sapfens solute carrier fa 3.23
432035 AA524725 Hs.162108 Hs.162108:ESTs 3.23
408868 AW292286 Hs.255058 Hs.255058:ESTs 3.23
429504 X99133 Hs.204238 Hs.204238:lip∞alin 2 (oncogene 24p3) 3.22
441085 AW136551 Hs.181245 Hs.181245:Homo sapiens cDNA FU12532 fis 3.22
426991 AK001536 Hs.214410 Hs.214410:Homo sapiens CDNA FU31573 fis 3.22
408901 AK001330 Hs.48855 (lxuslink)NM_018101:Homo εapienε hypoth 3.22
439979 AW600291 Hs.6823 NM.018092:Homo sapiens neuropilin (NRP) 3.22
453968 AA847843 Hs.62711 Hs.62711:Homo sapiens, clone IMAGE:33512 3.22
457465 AW301344 Hs.122908 NM_030928:Homo sapienε DNA replication f 3.22
426317 AA312350 Hs.169294 NM_003202:Homo sapfens transcription fx 3.21
414639 X67055 Hs.76716 NM_002217:Homo sapiens pre-alpha (globul 3.21
439975 AW328081 Hs.6817 NM_033453:Homo sapiens inosine triphosph 3.20
444261 AA298g58 Hs.10724 Hs.10724:mitxhondrial ribosomal protein 3.20
454033 AF107457 Hs.37035 NM_005515:Homo sapiens homeo box HB9 (HL 3.20
424837 BE276113 Hs.333034 NM_003491:Homo sapiens ARD1 homolog, N-a 3.20
427747 AW411425 Hs.180655 (locusliπk)NM_004217:Homo sapiens serine 3.20
436469 AK001455 Hs.5198 Hs.5108:Down syndrome critical region ge 3.10
400130 Hs.155560 NM_001746:Homo sapiens calπexin (CANX), 3.19
422293 X94453 Hs.114366 Hs.114366:pyιτoline-5-carboxylate synthe 3.19
400290 H18836 Hs.31608 (tocuslink)NM_017636:Homo sapiens transi 3.18 419239 AA468183 Hs 335798 (lxuslιπk)NM_033103 Homo sapiens rhophi 3 18
426215 AW963419 Hs 155223 NM.003714 Homo sapieπε εtaπnixalcin 2 ( 318
425743 BE396495 Hs 159428 NM.138761 Homo εapiens BCL2-asεocιated X 3 17
413313 NM.002047 Hs 293885 NM.002047 Homo sapiens glyoyl tRNA synth 3 17
422714 AB018335 Hs 119387 NM.014698 Homo sapiens KIAA0792 gene pro 317
408353 BE430838 Hs 44298 NM.015969 Homo sapiens mitxhondπal nb 3 17
400203 Hs 1390 NM.002794 Homo sapiens proteasome (proso 316
412870 N22788 Hs 82407 NM.022059 Homo sapiens chemokine (C-X-C 3 16
426088 AF038007 Hs 166196 NM.005603 Homo sapienε ATPase, Class I, 316
416984 H38765 Hs 80706 NM.000903 Homo sapiens NAD(P)H dehydroge 3 16
450635 AW403954 Hs 25237 NM.016647 Homo sapiens mesenchymal stem 3 16
406708 AI282759 AI282759 qt84a01 x1 NCI_CGAP_Co14 Homo s 3 16
452888 AW955454 Hs 30942 NM.004093 Homo sapienε ephnn B2 (EFNB2) 316
430127 AA219498 Hs 233952 Hε 233952 proteasome (prosome mxropain 3 16
417308 H60720 Hs 81892 NM.014736 Homo sapiens KIAA0101 gene pro 3 15
408116 AA251393 Hs 289052 NM.052842 Homo sapiens BCL2-lιke 12 (pro 3 15
402474 315
419488 AA316241 Hs 90691 NM_0069g3 Homo sapiens nucleophosmin/nuc 3 15
446595 T57448 Hs 15467 NM.017943 Homo sapiens hypothetical prot 315
444954 AW247076 Hs 12163 NM.003908 Homo sapienε eukaryotic transi 3 15
434263 N34895 Hs 79187 Hs 79187 coxsxkie virus and adenovirus 3 15
411165 NM 000160 Hs 69080 NM.000169 Homo sapienε galxtoεidase, al 315
430696 AA531276 Hs 59509 Hs 59509 ESTs, Weakly similar to similar 315
436391 AJ227892 Hs 146274 Hs 146274 ESTs 3 15
409142 AL136877 Hs 50758 Hs 50758 SMC4 structural maintenance of 3 14
445873 AA250970 Hs 251946 Hs 251946 Homo εapiens cDNA FLJ11840 fis 3 14
432370 AA308334 Hs 274424 NM.018846 Homo sapieπε N-xetylneuramim 3 14
430514 AA318501 Hs 241587 NM.021246 Homo sapiens lymphxyte antige 314
417791 AW96533g Hs 44269 Hs 44269 Homo sapiens cDNA FU37972 fis, 314
417115 AWg52792 Hs 334612 NM.003094 Homo sapiens small nuclear πb 3 13
411126 NM 01202 Hs 68879 (tocuslιnk)NM_001202 Homo sapiens bone m 3 13
456906 AF117646 Hε 156637 NM.012116 Homo sapiens Cas-Br-M (muπne) 313
425123 AW205274 Hs 154695 NM.000303 Homo sapiens phosphomannomutas 3 13
408056 AA312329 Hs 42331 Hs 42331 ephπn-A4 3 13
446386 AI032108 Hs 54424 Hs 54424 hepat∞yte nuclear factor 4, al 3 12
407804 AF228603 Hs 39957 NM.016445 Homo εapienε plxkεtπn 2 ( ou 312
412723 AA648459 Hs 335951 Hε 335951 hypothetical protein AF301222 312
407233 X16354 Hs 50964 (locuεlιnk)NM_001712 Homo εapienε carcin 3 11
407168 R45175 Hs 117183 Hε 117183 Homo sapiens mRNA, cDNA DKFZp5 3 11
452721 AJ269529 Hs 301871 Hs 301871 solute earner family 37 (glyo 3 11
426427 M86699 Hs 169840 Hs 169840 TTK protein kinase 3 11
409162 H25530 Hs 50868 Hs 50868 εolute earner family 22 (organ 3 10
412612 NM 000047 Hs 74131 NM.000047 Homo εapiens arylsulfataεe E ( 310
434861 AA206153 Hs 4209 NM.016491 Homo sapiens mitxhondπal πb 310
407944 R34008 Hs 239727 NM.024422 Homo sapienε desmxollm 2 (DS 3 10
414806 D14694 Hs 77329 (tocuslιnk)NM_014754 Homo sapiens phosph 309
454464 AW811606 Hs 271819 Hs 271819 mucin 17 309
415474 NM.014252 Hs 78457 NM.014252 Homo sapiens solute earner fa 309
422616 BE300330 Hs 118725 NM.012248 Homo sapiens selenophoεphate s 309
421470 R27496 Hs 1378 NM.005139 Homo sapiens annexin A3 (ANXA3 309
419551 AW582256 Hε 91011 NM.006408 Homo sapiens anteπor gradient 309
418691 AW752389 Hs 87296 Hs 87296 Homo sapienε cDNA FU20269 fis, 308
422163 AF027208 Hs 112360 Hs 112360 prominin like 1 (mouse) 308
447760 AI431328 Hs 348605 NM.052963 Homo sapiens mitxhondπal top 308
405506 308
429957 AW204530 Hs 99500 Hs 9g500 ESTs 308
410166 AK001376 Hs 59346 NM.018122 Homo sapienε hypothetical prot 308
422880 AF228704 Hs 193974 Hs 193974 glutathione reductase 308
442013 AA506476 Hs 375009 Hs 375009 Homo sapiens mRNA, cDNA DKFZp6 308
431722 AF161528 Hs 268049 (tocuslmk)NM_016101 Homo sapienε hypoth 308
421506 BE302796 Hs 105097 Hε 105097 thymidme kinase 1, soluble 308
433659 AK001301 Hs 3487 NM 018093 Homo sapiens hypothetical prot 307
439492 AF086310 Hs 103159 Hs Ϊ03159 ESTs, Weakly similar to T06291 307
417866 AW067903 Hs 82772 Hs 82772 collagen, type XI, alpha 1 307
412530 AA766268 Hs 266273 (l∞uslιnk)NM_024918 Homo sapiens chromo 307
412869 AA290712 Hε 82407 Hs 82407 chemokine (C-X-C motif) ligand 306
453132 AW951952 Hs 293724 Hs 293724 Homo sapiens cDNA FLJ12683 fis 306
424971 AA479005 Hs 154036 NM.003311 Homo sapiens tumor suppressing 306
427557 NM.002659 Hs 179657 NM.002659 Homo sapiens plasminogen ∞tiv 305
439273 AW139099 Hs 367692 Hs 367692 Homo sapiens cDNA FU25668 fis 305
431945 AW000827 Hs 11962 NM.030766 Homo sapiens apoptosiε regulat 305
435703 AW630133 Hs 83313 (lxuslιnk)NM_020192 Homo sapiens GK003 305
407289 AA135159 Hs 203349 Hs 203349 Homo sapiens cDNA FU12149 fis 304
403739 304
444664 N26362 Hs 11615 NM.016086 Homo sapiens map kinase phosph 304
409152 AA176585 Hs 194346 Hs 194346 Spιr-2 protein 304
409093 BE243834 Hs 50441 NM.015936 Homo sapiens CGI-04 protein (L 304
406545 303
450553 AW850613 Hs 8715 Hs 8715 hypothetical protein MGC3232 303
418867 D31771 Hs 89404 NM.002449 Homo sapiens msh homeo box hom 303
422976 AU076657 Hs 1600 Hs 1600 chaperonin containing TCP1, subu 303
434523 AA703709 Hs 23410 (l∞uslιnk)NM_016539 Homo sapiens sirtui 303
440088 BE559877 Hs 183232 NM.024839 Homo sapiens hypothetical prot 302 414907 X90725 Hs77597 NM.000998 Homo sapiens nbosomal protein 302
407103 AA424881 Hs 256301 Hs 256301 hypothetical protein MGC13170 302
434203 BE262677 Hs283558 NM.018509 Homo sapiens hypothetical prot 302
422283 AW411307 Hs 114311 NM.003504 Homo sapiens CDC45 cell divisi 302
412133 U83460 Hs 104557 NM.001859 Homo sapiens solute carπerfa 302
450334 AF035959 Hs 24879 Hs 24879 phosphatidic xid phosphatase t 302
417975 AA641836 Hs 30085 NM.024616 Homo sapiens hypothetical prot 302
420162 BE378432 Hs 95577 NM.052984 Homo sapiens cyclm-dependent 301
436561 BE560135 Hs 5232 NM.014165 Homo sapiens HSPC125 protein ( 301
426031 AA295251 Hs 166066 (locus!ιnk)NM_006697 Homo sapiens cispla 301
417678 X06560 Hs 82396 (lxuslιnk)NM_002534 Homo sapienε 2',5'- 301
417386 AL037228 Hs 301957 NM.018144 Homo εapieπs Sx61 alpha form 300
429983 W92620 Hs260855 (locuslιnk)NM_145175 Homo sapiens NSE1 ( 300
417526 AA568906 Hs 82240 Hs 82240 syntaxιn 3A 300
414732 AW410076 Hs 77152 Hs 77152 MCM7 minichromosome maintenance 300
409614 BE297412 Hs 55189 NM.016489 Homo sapiens 5'-nucleotιdase, 300
439053 BE244588 Hs6456 Hs 6456 chaperonin containing TCP1 , subu 300
411096 U80034 Hs 68583 NM.005932 Homo εapieπs mitochondπal int 2 g9
433312 AI241331 Hs 131765 Hs 131765 ESTs, Moderately similar to 13 299
420767 AF072711 Hs 99918 Hs 99918 carboxyl ester lipaεe (bile sal 299
429523 AK000788 Hs 205280 Hs 205280 Homo sapienε cDNA FU20781 fis 299
423242 AL039402 Hs 125783 Hs 125783 chromosome 1 open reading (ram 299
420552 AK000402 Hs 98806 Hs 98806 hypothetical protein FU20485 299
413380 AI904232 Hs75323 Hs 75323 prohibitin 299
421533 N71826 Hs 105465 NM.003095 Homo sapienε εmall nuclear πb 299
439352 BE614347 Hs 169615 NM.023080 Homo εapiens hypothetical prot 298
428023 AL038843 Hs 374530 Hε 374530 Homo sapiens cDNA FU23602 fi 298
431193 AW748505 Hs 296770 Hs 296770 KIAA1719 protein 298
457211 AW072565 Hs 32399 (lxuslιπk)NM_145240 Homo εapiens εtmila 288
410467 AF102546 Hs63931 NM.080759 Homo εapienε dxhshund homolog 297
422066 AW249275 Hs 343521 Hs 343521 malate dehydrogenase 2, NAD (m 297
418526 BE019020 Hs 85838 NM.004207 Homo sapiens solute earner fa 297
453012 T95804 Hs 31334 NM.012469 Homo sapiens chromosome 20 ope 297
412939 AW411491 Hs 75069 Hs 75069 serine hydraxymethyltransferase 297
413813 M96956 Hs 75561 NM.003212 Homo sapiens teratocarcinoma-d 297
418362 AL031714 Hs 84285 NM.003345 Homo sapiens ubiquitm-conjuga 297
431350 AI192528 Hs 164537 Hs 164537 ESTε 296
417911 AA333387 Hs 82916 Hε 82916 chaperonin containing TCP1, sub 296
413597 AW302885 Hs 117183 Hs 117183 Homo sapiens mRNA, cDNA DKFZpδ 296
409956 AW103364 Hs727 NM.002192 Homo sapiens inhibin, beta A ( 296
445462 AA378776 Hs 288649 (tocuslιnk)NM_024051 Homo sapienε hypoth 296
418245 AA088767 Hs 83883 NM.020182 Homo sapiens transmembrane, pr 296
408194 AA601038 Hs 191797 Hs 191797 ESTs 296
421959 AW751497 Hs 98370 NM 030622 Homo sapiens cytochrome P450, 296
459306 AW578452 AW578452 RC1-CT0252 030100-023-b07 CT025 296
425209 AL049761 Hs 155140 NM.001895 Homo sapiens casein kinase 2, 296
439659 AW970780 Hs59483 Hs 59483 leucine-nch repeat-conta mg 295
408683 R58665 Hs46847 NM.016614 Homo sapiens TRAF and TNF rxe 295
432843 BE250865 Hs 279529 NM.013237 Homo sapiens px19-lιke protein 295
406684 X16354 Hs 50964 (lxuslιnk)NM_001712 Homo sapiens carcin 295
410006 AW732308 Hs 57783 NM.003751 Homo sapiens eukaryotic transi 294
442577 AA292998 Hs 163900 Hs 163900 ESTs, Highly similar to winged 294
425003 AF119046 Hs 154149 NM.014481 Homo sapiens APEX nuclease (ap 294
449437 AI702038 Hs 100057 Hs 100057 seπne/thrxnine kinase 35 294
427779 AA9060g7 Hε 180780 NM.021238 Homo sapiens TERA protein (TER 294
446696 AF279265 Hε208476 NM.022911 Homo sapiens solute earner fa 294
414549 BE393069 Hs 183506 NM.024841 Homo sapiens hypothetical prot 293
410817 AI262789 Hs 93659 (lxuslιnk)NM_004911 Homo sapiens protei 293
419378 R24922 Hs 90078 Hs 90078 nucleotide-sugar tranεporter si 293
428376 AF119665 Hs 184011 Hε 184011 pyrophoεphatase (inorganic) 293
414416 AW409985 Hs 6084 (l∞uslιnk)NM_032737 Homo sapiens hypoth 293
434094 AA305599 Hs 238205 Hs 238205 hypothetical protein PRO2013 293
409012 AL117435 Hs49725 Hs 49725 DKFZP434I216 protein 293
429048 AI372949 Hs44241 Hs 44241 Homo sapiens cDNA FU21447 fis 293
426378 U80082 Hs 169600 Hs 169600 KIAA0826 protein 292
422397 AJ223366 Hs 116051 (lxuslιnk)NM_138768 Homo sapiens myelom 292
426715 AB037855 Hs 171917 Hs 171917 hypothetical protein FU11085 292
429539 AK001839 Hs 206501 (lxuslιnk)NM_020467 Homo εapieπs hypoth 292
443715 AI583187 Hs9700 NM.001238 Homo sapienε cyclin E1 (CCNE1) 292
453082 H18835 Hs 31608 (lxuslmk)NM_017636 Homo sapiens transi 292
433888 BE176078 Hs 30819 Hε 30819 hypothetical protein C40 292
424534 D87682 Hs 150275 Hs 150275 KIAA0241 protein 292
422558 NM.006420 Hs 118249 Hs 118249 ADP-πbosylation fxtor guamn 292
407777 AA161071 Hs 71465 Hs 71465 squalene epoxidase 292
429626 U36787 Hs 211571 NM.005333 Homo sapiens holxytochrome c 292
413374 NM.001034 Hs 75319 NM.001034 Homo sapienε πbonucleotide re 292
442159 AW163390 Hs278554 NM.007276 Homo sapiens chromobox homolog 292
400133 Hs 184693 NM.005648 Homo sapienε tranεcπption eio 291
419381 AB023420 Hs 90093 Hs 90093 heat sh∞k70kD protein 4 291
436827 H72187 Hs 356668 (locuslιnk)NM_005274 Homo sapienε guamn 291
426108 AA622037 Hs 166468 NM.004708 Homo sapiens programmed cell d 291
436278 BE396290 Hs5097 Hs 5097 synaptogyπn 2 291
425397 J04088 Hs 156346 NM.001067 Homo sapienε topoisomerase (DN 291 433487 U31814 Hs 3352 NM.0Q1527 Homo sapiens histone deacetyla 291
416933 BE561850 Hs 80506 NM.003090 Homo sapiens small nuclear πb 290
430287 AW182459 Hs 125759 Hs 725759 likely ortholog of mouse RING 290
434026 R15486 Hs 285218 (tocus!ιnk)NM_021213 Homo sapiens phosph 290
447698 A1420156 Hs 326733 NM.052858 Homo sapiens similarto RIKEN 290
411263 BE297802 Hs 69360 NM_006845 Homo sapiens kiπesin like 6 (m 290
432754 BE241691 Hs 3100 Hs 3100 lysyl tRNA synthetase 290
437016 AU076916 Hs 5398 Hs 5398 guanine onphosphate synthetase 290
446228 NM.016046 Hs 14415 NM.016046 Homo sapiens exosomal core pro 290
420421 AF281133 Hs 343589 Hs 343589 exosome component Rrp41 289
428385 AF112213 Hs 184062 Hs 184062 chromosome 20 open reading fra 289
414420 AA043424 Hs 76095 NM.052815 Homo sapiens immediate early r 289
457284 AF102850 Hs 227933 NM.013338 Homo sapiens Alg5, S cerevisi 289
401405 289
453111 AB014598 Hs 31720 NM.014799-Homo sapiens hephaestm (HEPH) 289
400247 Hs 356473 NM.006713 Homo sapiens xtivated RNA pol 289
421910 NM.014586 Hs 109437 NM.014586 Homo sapiens hormonally upregu 289
413610 AL117554 Hs 119908 NM.015934 Homo sapiens nucleolar protein 289
413588 AA971014 Hs 75432 NM.000884 Homo sapiens IMP (inosine mono 2.89
418661 NM.001949 Hs 1189 NM.001949 Homo sapiens E2F transcnption 288
427490 Z95152 Hs 178695 NM.002754 Homo sapiens mitogen xtivated 288
417634 W27202 Hs 82327 NM.000178 Homo sapiens glutathione synth 288
435099 AC004770 Hs 4756 NM.004111 Homo εapiens flap structure-εp 288
425811 AL039104 Hs 159557 NM.002266 Homo sapiens karyopheπn alpha 288
446849 AU076617 Hs 16251 (tocuslmk)NM_016207 Homo sapiens cleava 288
412974 R18978 Hs 75105 NM.006579 Homo sapiens emopa il binding 288
413179 N99692 Hs 75227 NM.005002 Homo sapiens NADH dehydrogeπas 288
407770 AW607831 Hs 38738 NM.014343 Homo sapiens claudin 15 (CLDN1 288
408847 AW290997 Hs 190153 Hs 190153 Homo sapiens cDNA FU33988 fis 287
448250 NM.016034 Hs 20776 (l∞uslιnk)NM_016034 Homo sapiens mitxh 287
428810 AF068236 Hs 193788 NM.000625 Homo sapiens nitπc oxide syπt 287
427505 AA361562 Hs 178761 Hs 178761 26S proteasome-associaled padl 287
418443 NM.005239 Hs 85146 Hs 85146 v-ets erythroblastosis virus E2 287
447343 AA256641 Hs 236894 Hs 236894 ESTs, Highly similar to S02392 287
409262 AK000631 Hs 52256 Hs 52256 hypothetical protein FU20624 287
443323 BE560621 Hs 9222 Hs 9222 estrogen rxeptor binding site a 287
450378 AW249181 Hs 154796 Hs 154796 Homo sapiens cDNA FU37976 fis 286
411761 AI733848 Hs 71935 NM 021220 Homo sapiens zinc finger prate 286
415691 AW963979 Hs 24723 Hs 24723 ESTs 286
417715 AW969587 Hs 86366 Hs 86366 ESTs 286
452099 BE612992 Hs 27931 Hs 27931 hypothetical protein FLJ10607S 286
436138 H53323 Hs 25717 Hs 25717 Homo sapiens cDNA FU23454 fis 286
432858 BE618609 Hs 279591 Hs 279591 Homo sapiens Similar to RNA p 286
434457 AF141332 Hs 200333 NM.018690 Homo sapiens apolipoprotein B4 286
444237 AA336878 Hs 9842 Hs 9842 ESTs 285
456362 AW973003 Hs 17S909 (l∞uslιnk)NM_024831 Homo sapiens nuclea 285
411393 AW797437 Hs 69771 NM.001710 Homo sapiens B-fxtor, properd 285
424270 AK001818 Hs 144407 NM.018283 Homo sapiens hypothetical prot 285
414396 BE548266 Hs 76057 (tocuslιnk)NM_000403 Homo sapiens galxt 285
426120 AA325243 Hs 166887 Hs 166887 copme I 285
448663 BE614599 Hs 356501 (tocuslιnk)NM_032335 Homo sapiens hypoth 285
443802 AW504924 Hs 9805 Hs 9805 exportιn 5 285
445863 R12234 Hs 13396 Hs 13396 Homo sapiens clone 25028 mRNA s 285
434808 AF155108 Hs 256150 Hε 256150 NY-REN-41 antigen 285
440334 BE276112 Hs 7165 NM 003904 Homo sapiens zinc finger prate 285
449057 AB037784 Hs 22941 Hs 22941 KIAA1363 protein 285
432680 T47364 Hs 278613 (tocuslιπk)NM_005532 Homo sapiens interf 284
446421 BE297434 Hs 15071 Hs 15071 chaperonin containing TCP1, sub 284
427239 BE270447 Hs 356512 Hs 356512 ESTs, Weakly similar to UBCA.A 284
425649 U30930 Hs 158540 (tocuslιnk)NM_003360 Homo sapiens UDP gl 2.84
429638 AI916662 Hs 211577 (locuslιnk)NM_004986 Homo sapiens kin∞t 284
435777 AW419202 Hs 286192 NM.032192 Homo sapiens protein phosphata 284
424441 X14850 Hs 147097 Hs 147097 H2A histone family, member X 284
407833 AW955632 Hs 66666 Hs 66666 chromosome 7 open reading frame 284
415083 AI632683 Hs 27179 Hs 27179 Homo sapiens cDNA FU12933 fis, 283
421462 AF016495 Hs 104624 NM.020980 Homo sapiens aquapoππ 9 (AQP9 2.83
443572 AA025610 Hs 9605 Hs 9605 cleavage and polyadenylation spe 283
443180 R15875 Hs 258576 NM.012129 Homo sapiens claudin 12 (CLDN1 283
413753 U17760 Hs 75517 NM.000228 Homo sapiens laminin, beta 3 ( 283
453028 AB006532 Hs 31442 NM.004260 Homo sapiens RxQ protein-like 283
425047 U34038 Hs 154299 NM.005242 Homo sapiens coagulation fxto 283
432593 AW301003 Hs 51483 Hs 51483 Homo sapiens, Similarto RIKEN 283
410197 NM.005518 Hs 59889 (tocuslιnk)NM_005518 Homo sapiens 3-hydr 283
413095 AA494359 Hs 30715 Hs 30715 potassium voltage-gated channel 283
417677 NM.016055 Hs 82389 NM.016055 Homo sapiens itxhondnal πb 283
425263 NM.001197 Hs 155419 NM.001197 Homo sapiens BCL2 interacting 282
437430 W44671 Hs 124 NM.014628 Homo sapiens gene predicted fr 282
428289 M26301 Hs 2253 Hs 2253 complement component 2 282
407137 T97307 282
400750 282
428788 AF082283 Hs 193516 NM.003921 Homo sapiens B-cell CLL/lympho 282
432633 AI796390 Hs 210667 Hs 210667 ESTs 282
432816 N38913 Hs 221575 Hs 221575 ESTs 282 410045 AA806930 Hs.58189 Hs.58189:eukaryotic translation initiati 2.82
454144 BE280478 Hs.182695 NM_024026:Homo sapiens mitochondrial rib 2.82
430387 AW372884 Hs.240770 Hs.240770:nuclearcap binding protein su 2.81
434583 AA095761 Hε.349092 Hs.349092:ESTs, Weakly similar to A42442 2.81
431512 BE270734 Hs.2795 Hs.2795:lxtate dehydrogenase A 2.81
428093 AW594506 Hs.104830 Hs.104830:ESTs 2.81
416047 BE439894 Hs.78991 NM_012080:Homo sapiens DNA segment, nume 2.81
447495 AW401864 Hs.18720 NM_004208:Homo sapiens programmed cell d 2.81
452199 BE255643 Hs.110695 Hs.110695:hypofhetical protein MGC3133 2.81
425998 AU076629 Hs.165950 NM.002011:Homo sapiens fibroblast growth 2.80
445921 AW015211 Hs.153799 Hs.153799:Homo εapiens cDNA FLJ38333 fis 2.80
422809 AK001379 Hs.121028 NM_018136:Homo sapiens hypothetical prot 2.80
417869 BE076254 Hs.82793 Hs.82793:prateasome (prosome, mxropain) 2.80
436127 W94824 Hs.11565 NM_080748:Homo sapiens chromosome 20 ope 2.80
418731 AI264688 Hs.1197 NM_002157:Homo εapienε heat εhxk lOkD p 2.80
432840 AK001403 Hs.279521 Hs.279521 :hypothetical protein FU20530 2.80
428028 U52112 Hs.182018 Hs.182018:interieukiπ-1 rxeptor-aεε∞ia 2.80
441181 AA416925 Hs.374811 Hs.374811 :Homo sapiens, similar to 4-1BB 2.80
409463 AI458165 Hs.17296 NM_023930:Homo sapienε hypothetical prot 2.79
450010 AW293801 Hs.255052 Hs.255052:ESTs 2.79
418960 NM.004494 Hs.89525 (lxuslink)NM_004494:Homo sapienε hepato 2.79
401179 2.79
419252 AW138434 Hs.129805 Hs.129805:ESTs 2.79
434750 BE019254 Hs.4112 Hs.4112:t-complex 1 2.79
412948 BE243313 Hs.334851 Hs.334851 :LIM and SH3 protein 1 2.79
400529 2.79
436414 BE264633 Hs.143638 NM.033661 :Homo sapiens WD repeat domain 2.79
436291 BE568452 Hε.344037 (lxuslink)NM_003981:Homo sapiens protei 2.79
427963 AI042582 Hs.181271 NM_016057:Homo sapienε CGI-120 protein ( 2.79
426459 AF151812 Hs.169992 NM_015966:Homo sapfens serologically def 2.79
413880 AI660842 Hs.110915 NM_021258:Homo sapienε interleukin 22 re 2.79
442468 N77737 Hs.8349 NM_138933:Homo sapiens apobec-1 compleme 2.79
413476 U25849 Hs.75393 NM_004300;Homo sapiens acid phosphatase 2.79
413278 BE563085 Hs.833 Hs.833:interferan-εtimulated protein, 15 2.79
430120 AW675298 Hs.233694 (lxusliπk)NM_018396:Homo sapiens putati 2.79
452875 BE275760 Hs.30928 NM.006114:Homo sapiens translocaεe of ou 2.79
417164 AA338283 Hs.81361 Hs.81361:heterogeneous nuclear ribonucle 2.79
407811 AW190902 Hs.40098 Hs.40098:cyεteine knot superfamily 1, BM 2.79
409636 AA305729 Hε.18272 (l∞uslink)NM_030674:Homo sapiens solute 2.78
447619 AI174800 Hs.19054 (l∞uslink)NM_018530:Homo sapiens hypoth 2.78
434845 BE267057 Hs.325321 Hs.325321 :WD repeat domain 18 2.78
414862 BE621310 Hs.923 Hs.923:single-stranded DNA binding prate 2.78
443639 BE269042 Hs.9661 Hs.9661:proteaεome (praεome, mxropain) 2.78
414045 NM 002951 Hs.75722 NM_002951:Homo sapiens ribophorin II (RP 2.78
430512 AF182294 Hs.241578 NM_016200:Homo sapiens U6 snRNA-aεε∞iat 2.78
432636 AA340864 Hs.278562 NM_001307:Homo sapiens claudin 7 (CLDN7) 2.78
414697 BE266134 Hs.76927 Hs.76927:tranεtocaεe of outer mitxhondr 2.78
420665 AW469240 Hs.371581 Hε.371581:ESTs 2.78
428474 AB023182 Hs.184523 Hs.184523:serine thrxnine kinase 38 lik 2.78
448093 AW977382 Hs.15898 Hs.15898:2,4-dienoyl CoA reductase 2, pe 2.77
443343 BE409809 Hε.301005 Hs.301005:histone H2A.F/Z variant 2.77
418313 BE244231 Hs.84038 NM_015937:Homo sapiens CGI-06 protein (L 2.77
424154 AF026004 Hs.141660 NM_004366:Homo sapiens chloride channel 2.77
456950 AF111170 Hs.306165 Hs.306165:ESTs, Highly similarto uπknow 2.77
432543 AA552690 Hε.152423 Hs.152423:Homo sapfens cDNA: FU21274fi 2.77
423271 W47225 Hs.126256 NM_000576:Homo sapiens interleukin 1, be 2.77
410595 AW629223 Hs.64794 NM_006978:Homo sapiens zinc finger prote 2.77
448140 AF146761 Hs.20450 NM_020125:Homo sapiens B lymphxyte xti 2.77
457757 AA434109 Hε.12271 NM_012162:Homo sapiens F-box and leucine 2.77
420186 NM 015925 i Hs.95697 Hs.95697:liver-εpxifie bHLH-Zip tranεcr 2.77
410094 BE147897 Hs.58593 NM_004128:Homo εapiens general transcrip 2.77
403817 2.77
459125 AA811363 Hs.29464 Hs.29464:Homo εapienε cDNA: FU23460 fis 2.77
432705 AI879473 Hs.157123 Hs.157123:ESTs 2.77
446658 AI440137 Hε.164989 NM_138492:Homoεapienε hypothetical prot 2.76
419485 AA489023 Hs.99807 Hs.99807:Homo sapiens mRNA; cDNA DKFZp31 2.76
432886 BE159028 Hs.279704 Hs.279704:chromatin accessibility comple 2.76
428438 NM.001955 Hε.2271 NM_001955:Homo sapiens endothelin 1 (EDN 2.76
414767 BE541381 Hs.178705 NM_033515:Homo εapienε MxGAP protein (M 2.76
406830 AI829848 Hs.342389 Hs.342389 : peptidylprolyl isomerase A (cy 2.76
432320 AW411066 Hs.274351 NM.016032:Homo sapiens zinc finger, DHHC 2.76
430450 R23553 Hs.241489 (l∞uslink)NM_015913:Homo εapienε hypoth 2.76
433808 NM 014062 Hε.3566 Hε.3566:ART-4 protein 2.75
431890 X17033 Hs.271986 NM_002203:Homo εapienε integrin, alpha 2 2.75
433369 Z49254 Hs.3254 NM_021134:Homo sapiens mitxhondrial rib 2.75
446946 AI878932 Hs.317 NM_003286:Homo sapienε topoisomerase (DN 2.75
432204 AI916132 Hs.121593 Hs.121593:Homo sapienε cDNA FU13123 fis 2.75
424438 AA340724 Hs.271912 Hs.271912:Homo εapienε cDNA FU38690 fis 2.75
433862 D86960 Hs.3610 NM_014873:Homo sapiens KIAA0205 gene pro 2.75
417080 BE392846 Hs.1063 Hs.1063:small nuclear ribonuclxprotein 2.75
428242 H55709 Hs.2250 Hs.2250:leukemia inhibitory fxtor (chol 2.75
416188 BE157260 Hs.79070 NM_002467:Homo sapiens v-myc myelxytoma 2.75
436014 AF281134 Hs.283741 NM.020158:Homo sapienε exosome component 2.75 419489 AW411280 Hs.90693 NM.013400:Homo sapiens replication initi 2.75
407971 AI469117 Hs.62918 Hs.62918:CDC91 cell division cycle 91-li 2.75
432403 AA550815 Hs.124840 (lxuslink)NM_138456:Homo sapiens hypoth 2.75
410775 AB014460 Hε.66196 NM_002528:Homo sapfens nth endonuclease 2.75
444197 BE266947 Hε.10590 NM_018683:Homo sapiens zinc finger prate 2.75
447250 AI878909 Hs.17883 NM_002707:Homo sapiens protein phosphata 2.75
406806 AW088535 Hε.350108 Hs.350108:ribosomal protein, large, P0 2.75
411580 AL080088 Hs.70877 NM_015421:Homosapiens DKFZP564K2062 pro 2.75
433662 W07162 Hs.150826 NM_020387:Homo sapiens RAB25, member RAS 2.74
426235 AI631964 Hs.34447 Hs.34447:Homo εapienε cDNA FU38512 fis, 2.74
413186 AU077141 Hs.374548 Hs.374548:solute earner family 16 (mono 2.74
419713 AW968058 Hs.92381 NM_019094:Homo εapienε nudix (nucleoside 2.74
410174 AA306007 Hs.59461 Hs.59461 :DKFZP434C245 protein 2.74
430720 U85768 Hε.247838 NM_002991:Homo sapiens small inducible c 2.74
429345 R11141 Hε.199695 Hs.199695:hypothetical protein MAC30 2.74
452767 AW014195 Hε.61472 Hs.61472:Homo sapiens, clone IMAGE:51841 2.74
414561 AI064813 Hs.195155 Hs.195155:solute carrier family 38, memb 2.73
423198 M81933 Hs.1634 Hs.1634:cell division cycle 25A 2.73
421038 AL080192 Hs.101282 Hs.101282:Homo sapiens mRNA; cDNA DKFZp4 2.73
444706 AK000398 Hs.11747 (lxuslink)NM_017798:Homo sapiens chromo 2.73
423908 AJ006422 Hs.135183 NM_006869:Homo sapienε centauriπ, alpha 2.73
433412 AV653729 Hs.8185 NM_021199:Homo εapiens sultide dehydrage 2.73
438485 W57578 Hs.378718 Hs.378718:Homo sapiens cDNA FU33433 fis 2.73
452461 N78223 Hs.108106 Hs.108106:ubiq uitin-like, containing PHD 2.73
407699 AA825974 Hs.32646 NM_024622:Homo sapiens hypothetical prot 2.73
412258 AA376768 Hs.96125 (tocuslink)NM_025151:Homo sapiens Rab co 2.73
450256 AA286887 Hs.24724 Hε.24724:Homo εapieπs cDNA FU39185 fis, 2.72
443905 AI215948 Hs.143969 Hs.143969:ESTs 2.72
413274 NM.004893 Hs.75258 NM_004893:Homo sapiens H2A histone fa il 2.72
408885 C02741 Hs.48712 NM_017948:Homo sapiens hypothetical prot 2.72
424685 W21223 Hs.151734 Hs.151734:nucleartransportfactor 2 2.72
424692 AA429834 Hs.151791 NM.014679:Homo sapienε KIAA0092 gene pro 2.72
413762 AW411479 Hs.848 NM_002014:Homo sapiens FK506 binding pro 2.72
418054 NM 002318 Hs.83354 NM.002318:Homo sapiens lysyl oxidase-lik 2.72
450164 AI239923 Hs.63931 NM_080759:Homo sapiens dachshund homolog 2.71
412115 AK001763 Hs.73239 Hs.73239:hypothetical protein FU10901 2.71
450897 W16741 Hs.351629 NM 014017:Homo sapiens HSPC003 protein ( 2.71
447349 AI375546 BE743847:601577765F1 NIH.MGC.9 Homo sapi 2.71
445413 AA151342 Hε.12677 (tocuslink)NM_016077:Homo εapiens CGI-14 2.71
448826 AI580252 Hε.255565 Hs.255565:Homo sapiens cDNA FU33892 fis 2.71
406671 AA129547 Hs.285754 NM_000245:Homo sapiens met proto-oncogen 2.71
433604 NM.013442 Hs.3439 Hs.3439:εtomatin (EPB72)-like 2 2.71
441020 W79283 Hs.35962 Hs.35962:Homo sapiens mRNA; cDNA DKFZp68 2.70
458933 AI638429 Hs.24763 NM_002882:Homo sapiens RAN binding prate 2.70
423787 AJ295745 Hs.236204 Hs.236204:nuclear pore complex protein 2.70
430462 AI584156 Hs.105640 Hs.105640:hypothetical protein BC007772 2.70
439656 AW138241 Hs.160602 Hs.160602:Homo sapienε cDNA FU36008 fiε 2.70
425236 AW067800 Hs.155223 NM_003714:Homo sapiens stanπtocalcin 2 ( ' 2.70
420085 AI741909 Hs.44680 Hs.44680:hypothetical protein FU20979 2.70
448296 BE622756 Hs.10949 Hs.10949:Homo εapienε cDNA FU14162 fis, 2.70
430200 BE613337 Hs.234896 Hs.234896:geminin 2.70
424308 AW975531 Hε.154443 Hs.154443:MCM4 minichromosome maintenanc 2.70
423453 AW450737 Hs.128791 NM_015939:Homo sapiens CGI-09 protein (L 2.70
421344 AW631030 Hs.103665 (tocuslink)NM_015873:Homo sapfens villin 2.70
446607 AI691065 Hs.155780 Hs.155780:ESTs 2.70
418558 AW082266 Hs.86131 Hs.86131:Fas (TNFRSF6)-asεociated via de 2.70
443835 AF016371 Hs.9880 NM_006347:Homo εapienε peptidyl prolyl i 2.70
413794 AF234532 Hs.61638 NM_012334:Homo εapiens myosin X (MYO10), 2.70
451481 AA300228 Hε.295866 (tocuslink)NM_030974:Homo εapiens hypoth 2.70
458820 BE552151 Hs.108118 Hs.108118:hypothetical protein FU22474 2.70
425905 AB032959 Hs.318584 NM_032173:Homo εapienε hypothetical prot 2.69
408089 H59799 Hε.42644 Hs.42644:thioredoxin-like 2 2.69
431201 AA678405 Hs.8854 Hs.8854:Pvt1 oncogene homolog, MYC xtiv 2.69
437897 AA770561 Hs.146170 Hs.146170:hypothetical protein FU22969 . 2.69
441703 AW390054 Hs.192843 NM_022145:Homo sapiens leucine zipper pr 2.69
433916 AW732839 • Hs.3631 NM_001551:Homo sapiens immunoglobulin (C 2.69
422516 BE258862 Hs.117950 NM_006452:Homo sapiens phosphoribosylami 2.69
416084 L16991 Hs.79006 NM.012145:Homo sapiens deoxythy idylate 2.69
427464 BE262956 Hs.178292 Hs.178292:protein O-fucosyltransferaεe 1 2.69
453876 AW021748 Hs.110406 Hε.110406:ESTε 2.69
424373 AJ133798 Hs.146219 NM_014427:Homo sapiens copiπe VII (CPNE7 2.69
411619 AI418609 Hs.71040 NM.017816:Homo sapienε hypothetical prot 2.69
413004 T35901 Hs.75117 Hs.75117:interieukin enhancer binding fa 2.69
420062 AW411096 Hs.94785 (tocuslink)NM_021809:Homo sapiens TGFB-i 2.69
446077 BE251048 Hs.22579 Hs.22579:Homo εapienε clone CDABP0036 mR 2.68
446269 AW263155 Hε.14559 NM_018131:Homosapiens hypothetical prot 2.68
428728 NM.016625 Hs.191381 Hs.191381 hypothetical protein LOC51319 2.68
400263 Hs.75309 NM_001961:Homo sapienε eukaryotic transi 2.68
421933 R98881 Hs.109655 NM_006746:Homo sapienε sex comb on midle 2.68
417750 AI267720 Hs.260523 Hs.260523:πeuroblastoma RAS viral (v-ras 2.68
429671 BE379335 Hs.211594 Hs.211594:proteasome (prosome, mxropain 2.68
421720 AF155096 Hε.107213 Hs.107213:fonmin binding protein 3 2.68
425601 AW629485 Hε.140720 NM_012083:Homo sapiens frequently rearra 2.68 425274 BE281191 Hs 155462 Hs 155462 MCM6 minichromosome maintenanc 268
433159 AB035898 Hs 150587 NM.020242 Homo sapiens k esin like 7 (K 268
406673 M34996 Hs 198253 Hs 198253 major histocompatibility compl 268
428206 AB020643 Hs 183006 Hs 183006 likely homolog of mouse hepaπ 268
429344 R94038 Hs 374664 NM.005538 Homo sapiens inhibin, beta C ( 268
427719 AI393122 Hs 134726 (tocuslιnk)NM_145060 Homo εapienε hypoth 268
408113 T82427 Hs 194101 Hs 194101 Homo sapiens cDNA FU20869 fi 268
457313 AF047002 Hs 241520 NM.005782 Homo sapiens transcπptional c 267
413142 M81740 HS 75212 (lxuslιnk)NM_002539 Homo sapiens omith 267
414998 NM.002543 Hs 77729 NM.002543 Homo sapiens oxidised low dens 267
432391 AI732374 Hs 339827 Hs 339827 ESTs, Weakly similar to protea 267
446342 BE298665 Hs 14846 Hs 14846 Homo sapiens mRNA cONA DKFZp56 267
447913 AW438602 Hs 191179 Hs 191179 ESTs 267
418738 AW388633 Hs 6682 Hs 6682 solute earner family 7, (cation 267
439586 AA922936 Hs 110039 Hs 110039 ESTs 267
427477 AW973119 Hs 178391 NM.021029 Homo sapiens nbosomal protein 267
421839 BE258778 Hs 108809 NM 006429 Homo sapiens chaperonin contai 267
400448 267
418416 U11700 Hε 84999 NM.000053 Homo sapiens ATPase, Cu++ traπ 267
445304 BE613206 Hs 279607 Hs 279607 Homo sapiens cDNA FLJ34399 fis 267
417601 NM 014735 Hs 82292 NM.014735 Homo sapiens KIAA0215 gene pro 266
444700 NM 003645 Hs 11729 NM.003645 Homo sapienε fatty xid Coenzy 266
431021 AI869664 Hs 351863 (lxuslιπk)NM_003312 Homo sapiens thiosu 266
453157 AF077036 Hs 31989 NM.015449 Homo sapiens N1CE-3 protein (N 266
453454 AW052006 Hs 374973 NM.004697 Homo sapiens PRP4 pre-mRNA pro 266
422599 BE387202 Hs 118638 Hs 118638 non metastatic cells 1 , protei 266
456248 AL035786 Hs 82425 NM.005717 Homo sapiens xtin related pro 266
427691 AW194426 Hs 20726 Hs 20726 ESTs, Moderately similar to hyp 266
419705 AW368634 Hs 154331 Hs 154331 ESTs 266
421254 AK001724 Hs 102950 NM.016128 Homo sapiens coat protein gamm 266
422719 BE017985 Hs 102558 Hs 102558 Homo sapiens cDNA FU40369 fis 266
446356 AI816736 Hs 14896 Hs 14896 zinc finger, DHHC domain contai 266
432435 BE218886 Hs 282070 Hs 282070 ESTs 266
433020 AI375726 Hs 227152 NM.016391 Homo sapiens hypothetical prot 265
436106 AI050715 Hs 2331 Hs 2331 E2F transcnption fxtor 5, p130 265
431127 U66618 Hs 250581 Hs 250581 SWI/SNF related, matnx assxi 265
425568 AW963118 Hs 161784 Hs 161784 ESTs 265
430508 AI015435 Hs 104637 Hs 104637 solute earner family 1 (gluta 265
414761 AU077228 Hs 77256 NM.004456 Homo sapiens enhancer of zeste 265
412738 N34731 Hs 74562 NM.078480 Homo sapiens fuse-binding prat 265
409893 AW247090 Hs 57101 Hs 57101 MCM2 minichromosome maintenance 265
421743 T35958 Hs 107614 Hs 107614 DKFZP564I1171 protein 264
428072 BE258602 Hs 182366 NM.016292 Homo sapieπε heat sh∞k protei 264
417957 H53497 Hs 83006 NM 016071 Homo sapiens itxhondnal πb 264
409119 AA531133 Hs 4253 Hs 4253 hypothetical protein MGC2574 264
447200 BE543146 Hs 281434 Hs 281434 Homo sapiens cDNA FLJ31373 fis 264
409214 AW405967 Hs 333388 Hε 333388 similarto CG3714 gene product 264
414883 AA926960 Hs 348669 Hs 348669 CDC28 protein kinase 1 264
433570 AI580053 Hs 109007 Hs 109007 Homo sapiens, Similar to LOC16 264
408633 AW963372 Hs 222088 NM.014109 Homo sapienε PRO2000 protein ( 264
447769 AW873704 Hs 320831 Hs 320831 chromosome 20 open reading fra 264
432964 AF118395 Hs 279865 NM.014317 Homo sapiens trans prenyltrans 263
444855 BE409261 Hs 12084 Hs 12084 Tu translation elongation fxto 263
428144 BE269243 Hs 182625 Hs 182625 VAMP (vesicle-assxiated membr 2.63
408137 AI694131 Hε 29002 Hs 29002 KIAA1706 protein 263
418703 NM.014448 Hs 87435 Hs 87435 Rho guanine exchange fxtor (GE 263
446051 BE048061 Hε 37054 Hs 37054 ephπn A3 263
430024 AI808780 Hs 227730 NM W0210 Homo εapienε integπn, alpha 6 263
406122 263
420988 AW006352 Hs 159643 Hε 159643 ESTs, Weakly similarto putati 263
436433 AW631437 Hs 5184 (tocuslιπk)NM_016397 Homo sapiens TH1-lι 263
417129 AI381800 Hs 300684 Hs 300684 calcitonin gene-related peptid 263
410397 AF217517 Hs 63042 NM_018457 Homosapιens DKFZp564J157 prot 263
419420 AA355435 Hs 30724 (lxuslink)NM_001516 Homo sapienε genera 263
400298 AA032279 Hs 61635 Hs 61635 six transmembrane epithelial an 2.63
412599 AU076782 Hs 248267 (lxuslιnk)NM_021126 Homo sapiens mercap 263
436199 R38946 Hs 127951 Hs 127951 Homo εapieπs cDNA FU14503 fis 263
425081 X74794 Hs 154443 Hs 154443 MCM4 minichromosome maintenanc 263
442025 AW887434 Hs 11810 NM.032026 Homo sapiens CDA11 protein (CD 262
437379 AL359575 Hs 23765 Hs 23765 membrane metallo-endopeptidase- 262
409703 NM 006187 Hs 56009 Hs 560092'-5'-olιgoadenylate εynthetase 262
419170 BE002798 Hε 287850 NM.002219 Homo sapiens integral membrane 262
418216 AA662240 Hε 283099 Hs 283099 AF15q14 protein 262
451926 AW134519 Hs 96125 (tocuslιnk)NM_025151 Homo sapiens Rab co 262
413781 J05272 Hs 850 (locuslmk)NM_000883 Homo sapiens IMP (1 262
407236 W79485 Hs 173980 Hs 173980 nuclear matnx protein NMP200 262
421405 AA251944 Hs 104058 NM.015957 Homo sapiens CGI 29 protein (L 262
428481 NM 012111 Hs 204041 NM.012111 Homo sapiens chromosome 14 ope 262
453335 AW857376 Hs 169238 NM.000149 Homo εapienε fucosyltraπsferas 262
441126 NM.000429 Hs 323715 (tocuslιnk)NM_000429 Homo sapiens methio 262
417404 NM.007350 Hs 82101 (locuslιnk)NM_007350 Homo εapiens plxks 262
432211 BE274530 Hs 273333 Hs 273333 hypothetical protein FU10986 262
446766 AF083208 Hs 16178 NM.012138 Homo sapiens apoptosis antagon 262 437033 AW248364 Hs.5409 (l∞uslink)NM_004875:Homo sapiens RNA po 2.62
412123 BE251328 Hs.73291 NM 018256:Homo sapfens WD repeat domain 2.62
454128 AL031259 Hs.367900 Hs.367900:programmed cell death 2 2.61
433037 NM 014158 Hs.279938 NM 014158:Homo sapiens HSPC067 protein ( 2.61 414438 AI879277 Hs.76136 (l∞uslink)NM_003329:Homo sapiens thiore 2.61
416221 BE513171 Hs.79086 (locuslink)NM 007208:Homo sapiens mitxh 2.61
443898 AW804296 Hs.9950 NM_014302:Homo sapiens Sec61 gamma (SEC6 2.61
410007 AW950887 Hs.57813 NMJ)14596:Homo sapiens zinc ribbon domai 2.61
412715 NM 000947 Hs.74519 NM_000947:Homo sapiens primase, polypept 2.61 449864 BE276386 Hs.111429 NM 032486:Homo sapiens dynxtin 4 (MGC32 261
448625 AW970786 Hs.178470 NM 024829:Homo εapienε hypothetical prot 2.61
452835 AK001269 Hs.30738 NM 018087:Homo sapiens hypothetical prot 2.61
410686 AI733735 Hs.114905 NM_033266:Homo sapiens ER to nucleuε εig 2.60
411400 AA311919 Hs.69851 NM_018983:Homo sapiens nucleolar protein 2.60 429770 AI766047 Hs.99736 Hε.99736:hypothetical protein MGC39350 2.60
425983 AK000226 Hs.165619 NM 031265:Homo sapiens mucin and cadheri 2.60
430237 AI272144 Hs.236522 Hs.236522:DKFZP434P106 protein 2.60
419607 R52557 Hs.91579 NM 033416:Homo sapiens similarto HYPOTH 2.60
419508 AW997938 Hs.90786 NM_003786:Homo sapiens ATP-binding casse 2.60 453258 AW293134 Hs.32597 NM 005977:Homo sapiens ring finger prate 2.60
457234 AW968360 Hs.14355 Hε.Ϊ4355:Homo εapiens CDNA FU13207 fis, 2.60
420911 U77413 Hs.100293 Hs.100293:O-linked N-xetylglucosamine ( 2.60
418478 U38945 Hs.1174 NM_000077:Homo sapiens cyclin-dependent 2.60
438533 AI440266 Hs.170673 NM_138969:Homo sapiens retinal short cha 2.60 421699 AL161994 Hs.107003 NM_021178:Homosapiens enhaπcerofinvas 2.60
452220 BE158006 Hs.212296 Hs.212296:ESTs 2.60
439148 AA372280 Hs.178576 (locuslinkJNM 030877:Homo sapiens cateni 2.60
453949 AU077146 Hs.36927 (locuslink)NM_006644:Homo sapiens heat s 2.59
451110 AI855040 Hs.265398 Hs,265398:ESTs, Moderately similar to hy 2.59 446291 BE397753 Hs.14623 Hs.14623:interferon, gamma-inducible pro 2.59
411125 AA151647 Hs.68877 Hs.68877;cytochrome b-245, alpha polypep 2.59
426858 NM.004182 Hs.172791 NM.004182:Homo εapienε ubiquitouεly-expr 2.59
442990 AA197226 Hs.19347 NM 032351:Homo sapiens mit∞hondrial rib 2.59
424197 AF096834 Hs.142989 NM_016982:Homo εapienε germ cell specif! 2.59 445580 AF167572 Hs.12912 NM 006109:Homo sapiens SKB1 homolog (S. 2.59
410219 T98226 Hs.171952 Hs.Ϊ71952:occludin 2.59
436415 BE265254 Hs.343258 NM_006191:Homo sapiens proliferation-ass 2.59
441153 BE562826 BE562826:601336534F1 NIH MGC.44 Homo sap 2.59
410570 AI133096 Hs.64593 NM_006356:Homo sapiens ATP εynthase, H+ 2.58 430594 AK000790 Hs.246885 NM 017958:Homo sapiens hypothetical prot 2.58
410315 AI638871 Hs.378965 Hs.378965:Homo sapiens cDNA FU37658 fis 2.58
443303 U67319 Hs.9216 NM 033340:Homo sapiens caspase 7, apopto 2.58
425725 NM 012243 Hs.159322 (tocusliπk)NM_012243:Homo sapfens εolute 2.58
449019 AI949095 Hs.67776 Hs.67776:Homo sapiens, clone IMAGE:54556 2.58 410442 X73424 Hs.63788 Hε.63788:propionyl Coenzyme A carboxylaε 2.58
456629 AW891965 Hs.367942 Hs.367942:Homo sapfens, clone IMAGE4701 2.58
454417 AI244459 Hs.110826 Hε.110826:tιinucleotide repeat containin 2.58
416330 AU077101 Hs.79222 Hs.79222:galxtosidase, beta 1 2.58
437712 X04588 Hs.85844 Hs.85844:πeurotrophic tyrosine kinase, r 2.58 423750 AF165883 Hs.298229 NM 012394:Homo sapiens prefoldin 2 (PFDN 2.58
412641 M16660 Hs.74335 Hs.74335:heat shock 90kD protein 1, beta 2.58
406180 2.58
416297 AA157634 Hs.79172 Hs.79172:solute carrier family 25 (mitoc 2.58
418803 U50079 Hs.88556 NM 004964:Homo sapiens histone de∞etyla 2.58 447532 AK000614 Hs.18791 NM H7899:Homo sapiens hypothetical prot 2.57
420309 AW043637 Hs.21766 Hs.21766:ESTs, Weakly εimilar to hypothe 2.57
447418 AA063074 Hs.18552 Hs.18552:E2IG2 protein 2.57
424142 AI678727 Hs.378970 Hε.378970:Homo sapiens CDNAFU35102 fis 2.57
428342 AI739168 Hs.349283 Hs.349283:Homo sapiens CDNAFU31753 fis 2.57 427254 AL121523 Hs.97774 Hs.97774:ESTs 2.57
458778 AW451034 Hs.326525 NM 001669:Homo sapiens arylsulfatase D ( 2.57
425689 W16480 Hs.24283 Hε.24283:Homo sapiens CDNA FU25952 fiε, 2.57
452700 AI859390 Hs.288940 NM_021259:Homo sapiens transmembrane pro 2.57
427678 BE267756 Hs.180312 NM_016065:Homo sapiens mit∞hondrial rib 2.57 ' 444656 AI277924 Hs.145199 Hs.145199:ESTs, Weakly similarto hypoth 2.57
425206 NM 002153 Hs.155109 NM 002153:Homo εapiens hydroxysteroid (1 2.57
416412 NM.014742 Hs.79305 Hs.79305:KIAA0255 gene product 2.56
427648 AI376722 Hs.180062 Hs.180062:proteasome (prosome, mxropain 2.56
419193 D29643 Hs.34789 NM_005216:Homo sapiens dolichyl-diphosph 2.56 409964 AW368226 Hs.67928 Hs.67928:ESTs 2.56
431910 AKO00142 Hs.101774 Hs.101774:hypothetical protein FU23045 2.56
413010 AA393273 Hs.75133 NM_003201:Homo sapiens transcription fx 2.56
452264 AU077013 Hs.28757 Hs.28757:transmembrane 9 superfamily mem 2.56
419423 D26488 Hs.90315 Hs.90315:KIAA0007 protein 2.56 425221 AV649864 Hε.155188 NM_005642:Homo εapienε TAF7 RNA polymera 2.56
437623 D63880 Hs.5719 NM.014865:Homo sapiens chromosome conden 2.56
444184 T87841 Hs.282990 (tocusliπk)NM_033550:Homo sapiens chromo 2.56
418650 BE386750 Hs.86978 Hs.86978:pralyl endopeptidase 2.56
425368 AB014595 Hs.155976 (locusliπk)NM_003588.Ηomo sapiens culliπ 2.56 420614 AL110291 Hs.99364 Hs.99364:abhydrolaεe domain containing 1 2.56
427876 A1494291 Hε.369171 Hs.369171:ESTs 2.56
418862 BE550964 Hs.89399 NM_005176:Homo sapiens ATP synthase, H+ 2.56
416432 BE391767 Hs.79322 (lxuslink)NM_005051:Homo sapiens glutam 2.55 458814 AI498957 Hs 351937 Hs 351937 πbosomal protein, large P2 255
448153 Y10805 Hs 20521 NM.001536 Homo sapiens HMT1 hnRNP methyl 255
454003 AA058944 Hs 116602 Hs 116602 hypothetical protein BC009115 255
411950 T28407 Hs 81564 NM.002619 Homo sapiens platelet fxtor 4 255
457400 AF032906 Hs 252549 NM 001336 Homo sapiens cathepsin Z (CTSZ 255
426410 BE298446 Hs 305890 NM.138578 Homo sapiens BCL2-lιke 1 (BCL2 255
402829 255
425843 BE313280 Hε 159627 NM.004632 Homo sapiens death asεxiated 255
400995 255
452945 AW978187 Hs 79103 NM.030579 Homo εapienε cytochrome b5 out 255
417144 AA382104 Hs 81337 Hs 81337 Ixtiπ galxtoside-b ding, so 255
422192 AA305159 Hs 113019 NM.015931 Homo sapienε fls485 (LOC51066) 255
424755 AB033094 Hs 152925 Hs 152925 KIAA1268 protein 255
410012 AW015832 Hs 57898 (tocuslιnk)NM_017819 Homo εapiens hypoth 255
431236 AV656840 Hs 285115 NM.001560 Homo sapiens interleukin 13 re 255
449042 AW294985 Hs 30715 Hs 30715 potassium voltage-gated channel 255
420281 AI623693 Hs 323494 (l∞uslιnk)NM_017964 Homo sapiens hypoth 255
418681 AA287786 Hs 23449 Hs 23449 insulin rxeptor tyrosine kinas 255
406629 AW277078 Hs 181165 Hs 181165 eukaryotic translation elongat 255
421612 AF161254 Hε 106196 (tocuslιnk)NM_016579 Homo sapiens 8D6 an 254
446715 AI337735 Hs 173919 Hs 173919 ESTε Weakly similar to neuron 254
431183 NM 006855 Hs 250696 NM.006855 Homo sapiens KDEL (Lys Asp-Glu 254
407722 BE252241 Hs 38041 NM.003681 Homo sapiens pyπdoxal (pyπdo 254
427368 BE041451 Hs 177507 Hs 177507 hypothetical protein HSPC155 254
426268 AF083420 Hs 168913 NM.003576 Homo εapienε εeπne/threoπme 254
409632 W74001 Hs 55279 NM.002639 Homo sapiens seπne (or cystei 254
442875 BE623003 Hs 23625 Hs 23625 Homo sapiens clone TCCCTA00142 254
456031 AA335996 Hs 355907 Hs 355907 ESTε, Weakly similar to protei 254
442432 BE093589 Hs 38178 NM.024629 Homo sapiens hypothetical prot 254
437741 BE561610 Hs 5809 NM.020470 Homo sapienε putative transmem 254
448775 AB025237 Hs 388 NM.002452 Homo sapiens nudix (nucleoside 254
414368 W70171 Hs 75939 NM.012474 Homo sapiens undine monophosp 254
432876 AW248272 Hs 279652 NM.015956 Homo sapienε mit∞hondπal πb 253
431731 BE266322 Hs 211374 (tocuslιπk)NM_145051 Homo sapiens hypoth 253
425994 AK000207 Hs 165803 NM.017708 Homo sapienε hypothetical prot 253
445982 BE410233 Hs 13501 (l∞uslιnk)NM_014303 Homo sapiens pescad 253
444232 W56010 Hs 347297 (tocuslιnk)NM_013397 Homo sapienε over-e 253
435655 AW105663 Hs 6947 (tocuεlιnk)NM_014159 Homo sapiens Huntin 253
417686 AA769155 Hs 235498 Hs 235498 hypothetical protein FU14075 253
417933 X02308 Hs 82962 NM.001071 Homo sapienε thymidylate synth 253
426812 AF105365 Hs 172613 NM.006598 Homo sapiens solute earner fa 253
452313 Y00486 Hs 28914 Hs 28914 adenme phosphoπbosyltransfera 253
438317 AA826401 Hs 122393 Hε 122393 ESTs 253
409299 AA045650 Hs 53125 NM.004597 Homo εapienε εmall nuclear πb 253
423599 AI805664 Hs 31731 (l∞uεlιnk)NM 012094 Homo sapiens peroxi 253
412525 AA581439 Hs 152328 Hs 152328 ESTs 253
424291 AL120051 Hs 144700 NM.004429 Homo sapiens ephπn B1 (EFNB1) 253
427581 NM 014788 Hs 179703 NM.014788 Homo sapiens tripartite motif- 253
414987 AA524394 Hs 294022 NM.032865 Homo sapiens hypothetical prot 253
434274 AA628539 Hs 57783 Hs 57783 eukaryotic translation imtiati 253
400282 Hs 289101 NM.005313 Homo sapiens glucoεe regulated 253
425322 U63630 Hs 155637 NM.006904 Homo εapienε protein kinase, D 253
453344 BE349075 Hs 44571 Hs 44571 ESTs 253
449915 NM.004529 l Hs 404 NM.004529 Homo sapiens myeloid/lymphoid 253
417691 AU076610 Hs 82399 NM.007357 Homo sapiens component of olig 252
439012 BE383814 Hs 6455 NM.006666 Homo sapienε RuvB like 2 (E c 252
434931 AW968941 Hs 166254 Hs 166254 likely ortholog of rat vxuole 252
411678 AI907114 Hs 71465 NM.003129 Homo sapiens squalene epoxidas 252
442315 AA173992 Hs 7956 Hs 7956 ESTε 252
447140 AF070537 Hs 17481 NM.138391 Homo εapienε hypothetical prot 252
422385 BE549407 Hs 115823 (lxuεlιπk)NM_006638 Homo sapiens πbonu 252
433517 AW022133 Hs 189838 Hs 189838 ESTs 252
450230 AW016607 Hs 201582 Hs 201582 ESTs 252
432866 BE395875 Hs 279609 NM.014342 Homo sapiens mitxhondπal car 252
433001 AF217513 Hs 279905 NM.016359 Homo sapienε nucleolar protein 252
440773 AA352702 Hs 37747 NM.022767 Homo sapiens hypothetical prot 252
440587 AL138461 Hs 323084 (l∞uslιnk)NM_031209 Homo sapiens tRNA-g 252
422813 AV656571 Hs 121068 (lxuslιnk)NM_003270 Homo sapienε transm 252
424259 AK001776 Hs 143954 (tocuslιnk)NM_018270 Homo sapiens chromo 252
436075 BE090176 Hs 179902 NM.080546 Homo sapiens CDw92 antigen (CD 252
453204 R10799 Hε 191990 Hs 191990 ESTs 252
453665 AA626250 Hs 326184 Hs 326184 Homo sapiens nuclear protein p 252
432353 NM.016558 Hs 274411 NM.016558 Homo sapiens SCAN domain conta 252
433271 BE621697 Hs 14317 NM.018648 Homo sapiens nucleolar protein 251
431770 BE221880 Hs 268555 NM.012255 Homo sapiens 5'-3' exoπbonucl 251
444019 BE173977 Hs 10098 NM.019082 Homo sapiens putative πucleola 251
428839 AI767756 Hs 82302 (tocuslιnk)NM_147174 Homo sapienε hepara 251
404826 251
429669 BE185499 Hs 2471 NM.014878 Homo sapiens KIAA0020 gene pro 251
434474 AL042936 Hs 211571 (lxuslιnk)NM_005333 Homo sapiens holxy 251
424482 BE268621 Hs 149155 (lxuslιnk)NM_003374 Homo sapiens voltag 251
450422 AA743525 Hs 60300 NM.033414 Homo sapiens hypothetical prot 251
440214 AA247118 Hs 049 (lxuslmk)NM_018386 Homo sapienε hypoth 251 421168 AF182277 Hs.330780 Hs.330780:cytochrome P450, εubfamily IIB 2.51
435750 AB029012 Hs.4990 Hε.4990:KIAA1089 protein 2.51
452101 T60298 Hs.10844 NM_052972:Homo sapiens leucine-rich alph 2.51
436043 AW963838 Hε.168830 Hs.T68830:Homo sapienε cDNA FU12136 fis 2.51
424909 S78187 Hs.153752 (lxuslink)NM_004358:Homo sapiens cell d 2.51
435677 AA694142 Hs.6685 Hs.6685:thyraid hormone rxeptor interx 2.51
406363 2.51
452018 AW102941 Hs.211265 Hε.211265:ESTε 2.51
409591 AA532963 Hs.9100 Hε.9100:hypothetical gene supported by A 2.51
421937 AI878857 Hs.109706 NM.016185:Homo sapiens hematological and 2.51
416293 BE244454 Hs.79162 Hs.79162:εtructure spxific rxognition 2.51
421532 AW138207 Hs.146170 NM_022842:Homo sapiens hypothetical prot 2.50
434584 D57341 Hs.188361 Hs.188361:Homo εapienε cDNA FU12807 fiε 2.50
428109 AW732918 Hs.182490 Hs.182490:leuciπe-rich PPR- otif contain 2.50
426053 U68105 Hs.172182 NM_002568:Homo sapiens poly(A) binding p 2.50
432642 BE297635 Hs.3069 NM_004134:Homo sapiens heat sh∞k 70kD p 2.50
452390 AI864142 Hs.29288 (lxuslink)NM_022759:Homo sapiens eπdo-b 2.50
429023 NM.000312 Hs.2351 NM 000312:Homo sapiens protein C (inxti 2.50
400076 2.50
420596 NM 002692 Hε.99185 NM_002692:Homo sapiens polymerase (DNA d 2.50
422244 Y08890 Hs.113503 NM_002271:Homo sapiens karyopheriπ (impo 2.50
410723 AA100683 Hs.372108 Hs.372108:ESTs 2.50
435496 AW840171 Hs.265398 Hs.265398:ESTε, Moderately similar to hy 2.50
425159 NM 004341 Hs.154868 NM_004341:Homo sapiens carbamoyl-phospha 2.50
433626 AF078859 Hs.86347 NM.013341 :Homo sapiens hypothetical prot 2.50
448391 H71025 Hs.21075 NMJ)16328:Homo sapiens GTF2I repeat doma 2.50
TABLE 10B
Pkey: Unique Eos probeεet identifier number
CAT number. Gene cluster number Accession: Genbank axession numbers
Pkey CAT Number Accession
406685 0.0 M18728 434414 35978.1 AF134164 BF809407 AA218567 BF842863 AI267168 BF876178 BG999253 AW861851 AW858362 AI817548 BF771300 AA113928 AA223422
AA055556 BF773400 BF998868 BE081333 BE073424 BE142245 H59571 H59570 BF871558 BF871064 BE001132 BF826831 AW754298
AA223267 BG997895 BG997897 AW991957 AA534354 BG319501 BF736309 AI694265 AA045564 BG950256 AI829309 BG987850 BE093175
BF854337
432407 MH1429.12 BG036675 BF772005 BF771866 BG960386 BG960381 NM.005712 AF110315 BE074534 BE182776 BE158000 BE157999 BE714315 AW818104
AW847519 AA099426 AW817981 AW856396 BG961122 AA224498 AA308542 AW821833 BF902155 AI732411 BG778834 BG283641 BE748279
BE748870 BG319540 BE748864 BF739224 BG986155AK057283 BI861466AA663341 AA457591 BG949294AW392886AA071122AA227849
AA584918 BG959570 BF773486 AL041698 BF959013 R87170 C16859 BF770411 BF771298 AI075321 L13823 AA216700 BF771864 AW861859
BE537068 C18935 AA155719 BF771172 BF769107 BF804964 AW818172 AW818143 AW392930 AW817057 AW858044 BF746211 AA179928
AW861687 AW821826 BI055726 BF242643 AA207189 BF770412 BF771157 BG430030 AA055592
406708 0.0 AI282759 459306 223120 -4 AW578452 447349 1063443.1 BE743847 AW809603 BM469626 AI375546 441153 2644803 BE562826 BE378727
TABLE 10C
Pkey: Unique number corresponding to an Eoε probeεet Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled "The DNA ■ sequence of human chromosome 22." Dunham I. et al. Nature (1999) 402:489495.
Strand: Indicates DNA strand from which exons were predicted. NLposition: Indicates nucleotide positions of predicted exons. Pkey Ref Strand NLposition
404519 8152000 Plus 12817-13000 406399 9256288 Minus 63448-63554 403220 7630969 Plus 64338-64517 404661 9797073 Plus 33374-33675,33769-34008 402496 9797769 Minus 8615-9103 403055 8748904 Minus 109532-110225 400965 7770576 Minus 173043-173564 403218 7630969 Plus 58039-58149 401866 8018106 Plus 73126-73623 403221 7630969 Plus 66294-66438,66936-67124 401519 6649315 Plus 157315-157950 405451 7622517 Minus 145949-146227 403532 8076842 Minus 81750-81901 402944 9368423 Plus 110411-110716,111173-111640 403219 7630969 Plus 61858-61995 403381 9438267 Minus 26009-26178 403485 9966528 Plus 2888-3001,3198-3532,36554117 405484 5922025 Plus 199214-199579,199672-199920,200262-20049 404684 9797403 Minus 110881-111020 402474 7547175 Minus 53526-53628,55755-55920,57530-57757 405506 6466489 Plus 80014-80401,80593-81125 403739 7630882 Plus 44563-44766,4820948483,52255-52495 406545 7711510 Plus 145662-145781,147854-147984,148098-14824
401405 7768126 Minus 69276-69452,69548-69958
400750 8119067 Plus 198991-199168,199316-199548
401179 9438647 Plus 113477-113893
400529 9796988 Plus 138232-138423
403817 8962065 Plus 110297-111052
400448 9887687 Minus 177372-177674
406122 9144087 Minus 30940-31386
406180 7283201 Minus 38923-39107
402829 8918414 Plus 101532-101852,102006-102263
400995 8099094 Plus 141186-141601
404826 6572184 Plus 47726-48046
406363 9256114 Plus 14403-14602,17000-17147,17241-17368
Table 11 A liεts about 958 genes up-regulated in colon cancer compared to normal adult tissues excluding non malignant colon tissueε (whole colon and colon epithelium) that are likely to encode proteins amenable to modulation by small motecules, peptides, or antibodies These were selxted from the starting collxtion of 59680 probesets on the Affymetπx/Eos Hu03 GeneChip® array as follows the ratio of "average" colon to "average" normal adult tissues was greater than or equal to 30, the "average" colon level was set to the 90th percentile value amongst colon pπmary cancer specimens and colon liver deπved metatases, the "average" normal adult tissue level was set to the 70th percentile value amongst non malignant tissues minus the coloπic derived samples, the "average" colon value was greater than or equal to 50 units, and the predicted protein contained a structural domain that is indicative of have an oncogenic function or of transducing an intracellular signal, or of being modulatable by small molxules, peptides, or antibodies (e g pkiπase, death-domain, 7tm, phosphatase, or lon.transporter) In order to remove gene-spxific bxkground levels of non spxific hybndization, the 15th percentile value amongst the non- malignant tissues was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 11 A 958 genes up-regulated in colon cancer compared to normal adult tissues excluding non-malignant colon tissues (whole colon and colon epithelium)
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of tumor to normal adult tissues
Pkey ExAccn UnigenelD Unigene Title R1
436749 AA584890 Hs5302 NM.006149 Homo sapiens Ixtin, galxtosi 37 18
406690 M29540 Hs 220529 (lxuslιnk)NM_004363 Homo sapiens carcin 31 24
407242 M18728 (lxuslιπk)NM_002483 Homo sapienε carcin 2481
406685 M18728 (lxuεlιnk)NM_002483 Homo εapiens carcin 2054
431912 AI660552 Hs356183 Hs 356183 ESTs, Weakly similar to S3B4.H 2038
428934 AF039401 Hs 194659 NM 001285 Homo sapienε chloπde channel, 20 13
406667 M12523 1989
437935 AW939591 Hs5940 NM.033049 Homo εapienε mucin 13, epithel 1968
446787 U67167 Hs315 NM.002457 Homo sapiens mucin 2, intestin 1955
423541 AA296922 Hs 129778 NM.014471 Homo εapieπs senne protease i 1833
421341 AJ243212 Hs 374281 NM.007329 Homo sapiens deleted in malign 1747
414386 X00442 Hs75990 NMJ05143 Homo sapiens haptoglobin (HP), 1737
416768 AA363733 Hs1032 NM.006507 Homo sapiens regenerating isle 1699
422578 AF239666 Hs 1545 NM.001804 Homo sapienε caudal type homeo 1515
441031 AI110684 Hs7645 NM.005141 Homo εapiens fibπnogen, B bet 1502
421582 AI910275 Hs350470 NM.003225 Homo sapiens trefoil fxtor 1 1423
407243 AA058357 Hs74466 (l∞uslιnk)NM_006890 Homo sapiens carcin 14 12
422260 AA315993 Hs 105484 NM.032044 Homo sapiens regenerating gene 1364
432542 AW083920 Hs 16098 NM.020384 Homo sapiens claudin 2 (CLDN2) 1348
424212 NM 005814 Hs 143131 NM.005814 Homo sapiens glycopratein A33 1343
418888 AU076801 Hs 89436 NM.004063 Homo sapienε cadhenn 17, LI c 1320
453863 X02544 Hs572 Hs 572orosomucoid 1 1306
413719 BE439580 Hs75498 NM.004591 Homo sapiens small inducible c 1258
436217 T53925 Hs107 NM 004467 Homo sapiens fibπnogen-like 1 1234
421100 AW351839 Hs 124660 Hs 124660 ESTs, Moderately similar to 21 11 72
409153 W03754 Hs 50813 NM.017625 Homo sapiens intelxtm (ITLN) 11 72
452316 AA298484 Hs 61265 NM 138805 Homo sapiens family with seque 11 49
406399 11 25
414463 T69078 Hs76177 NM.001633 Homo sapiens alpha-1-mιcrcglob 11 18
421964 X73079 Hs288579 NM.002644 Homo sapiens polymeπc immunog 11 12
407007 U22961 Hs 184411 NM.000477 Homo sapiens albumin (ALB), mR 11 01
423673 BE003054 Hs 1695 NM.002426 Homo sapiens matnx metallopro 1070
447400 AK000322 Hs 18457 NM.017763 Homo sapiens hypothetical prot 1069
450685 L15533 Hs423 NM.138938 Homo sapiens pancreatitis asso 1057
427583 M82962 Hs 179704 NM.005588 Homo sapienε mepππ A, alpha ( 1048
418007 M13509 Hs83169 NM.002421 Homo εapienε matnx metallopro 1039
406741 AA058357 Hs74466 (l∞uslιnk)NM_006890 Homo sapiens carcin 1020
422424 AI186431 Hs296638 Hs 296638 prostate differentiation fxto 10 19
423371 AU076819 Hs1650 NM.000111 Homo sapiens solute earner fa 9 91
452304 AA025386 Hs 61311 Hs 61311 ESTs, Weakly similar to S10590 972
422106 D84239 Hs 111732 NM.003890 Homo sapiens IgG Fo binding pr 970
430569 AF241254 Hs 178098 NM.021804 Homo sapiens angioteπsin I con 965
406687 M31126 Hs 352054 Hs 352054 pregnancy spxific beta-1-glyc 952
428355 BE256452 Hs2257 NM.000638 Homo sapiens vitronxtin (seru 947
422281 M36803 Hs346935 NM.000613 Homo sapiens hemopexin (HPX), 941
413585 AI133452 Hs75431 NM.000509 Homo sapiens fibππogen, gamma 939
422664 AA315933 Hs 120879 Hs 120879 Homo εapieπs, clone MGC 32871 931
417931 W95642 Hs 82961 Hs 82961 Homo sapiens, clone MGC 225881 930 422487 AJ010901 Hs 198267 NM.018406 Homo sapiens mucin 4, trxheob 901
413936 AF113676 Hs 297681 NM.000295 Homo sapienε seπne (orcystei
424687 J05070 Hs 151738 NM.004994 Homo sapiens matnx metallopro
420344 BE463721 Hs 97101 NM.014373 Homo sapiens putative G protei 871
446921 AB012113 Hs 16530 NM.002988 Homo sapiens small inducible c 867
428470 AC002301 Hs 184507 Hs 184507 Homo sapienε, similar to Homol 847
452594 AU076405 Hs 29981 Hs 29981 solute camerfamily 26 (sulfa 847
422310 AA316622 Hs 98370 (locuslιnk)NM.030622 Homo sapiens cytoch 843
421907 BE018556 Hs 109358 Hs 109358 ATPase, Class V, type 10B 834
424326 NM 014479 Hs 145296 NM.014479 Homo sapiens ADAM like dxysi 812
435538 AB011540 Hs 4930 Hs 4930 low density lipoprotem rxeptor 809
413881 L00190 Hs 75599 (lxuslιπk)NM_000488 Homo sapiens senne 796
443426 AF098158 Hs 9329 (lxuslιnk)NM.012112 Homo sapiens chromo 792
436972 AA284679 Hs 25640 Hs 25640 claudin 3 789
430677 Z26317 Hs 359784 NM.001943 Homo sapiens desmoglein 2 (DSG 787
409632 W74001 Hs 55279 NM.002639 Homo sapiens senne (or cystei 771
423803 NM 005709 Hs 132945 (tocuslιnk)NM_005709 Homo sapiens PDZ-73 758
430272 X04898 Hs 237658 Hs 237658 apolipopratem A II 748
451035 AU076785 Hs 430 NM.002670 Homo sapiens plastiπ 1 (I isof 731
422330 D30783 Hs 115263 NM.001432 Homo sapienε epiregu n (EREG) 731
425976 C75094 Hs 334514 NM.025257 Homo εapiens chromosome 6 open 729
411825 AK000334 Hs 352415 NM.017767 Homo sapienε solute earner fa 723
451917 AW391351 Hs 50820 Hs 50820 hypothetical cardix/skeletal 721
410418 D31382 Hs 63325 NM.019894 Homo sapiens transmembrane pro 7 12
418318 U47732 Hs 84072 NM.004616 Homo sapiens transmembrane 4 s 712
414617 AI339520 Hs 288817 (tocuslιnk)NM_025130 Homo sapiens hypoth 7 10
447342 AI199268 Hs 19322 Hs 19322 Homo sapiens, Similar to RIKEN 706
452194 AI694413 Hs 373599 Hs 373599 EST 702
414816 Y13709 Hs 77399 NM.001265 Homo sapienε caudal type homx 697
417491 AW376842 Hs 1085 NM.004963 Homo εapiens guanylate cyclase 696
423445 NM.014324 Hs 128749 NM.014324 Homo sapiens alpha methylxyl 696
403220 695
415992 C05837 Hs 145807 Hs 145807 hypothetical protein FLJ13593 687
449722 BE280074 Hs 23960 Hs 23960 cyclm BI 687
414798 AI286323 Hs 97411 Hs 97411 hypothetical protein MGC12335 680
415214 AI445236 Hs 125124 NM.004442 Homo sapiens EphB2 (EPHB2), to678
411975 AI916058 Hs 144583 n's 144583 Homo sapienε, clone IMAGE 3462 676
422511 AU076442 Hs 117938 NM.000494 Homo εapienε collagen, type XV 666
408983 NM.000492 Hs 663 NM.000492 Homo sapiens cystic fibrosis t 665
431301 AA502384 Hε 151529 Hs 151529 ESTs 662
428970 BE276891 Hs 194691 NM.003979 Homo sapiens retinoic xid d 659
424273 W40460 Hs 144442 NM.003561 Homo sapiens phospholipase A2 656
431657 AI345227 Hs 105448 Hs 105448 protein kinase, lysine deficie 654
431330 X69532 Hs 2777 NM.002215 Homo sapiens inter-alpha (glob 653
425983 AK000226 Hs 165619 NM.031265 Homo sapiens mucin and cadheπ 650
408243 Y00787 Hs 624 NM.000584 Homo sapienε interleukin 8 (IL 647
428187 AI687303 Hs 285529 Hs 285529 G protein-coupled receptor 49 646
408704 AA056635 Hs 5366 NM.139053 Homo sapiens epidermal growth 645
428753 AW939252 Hs 192927 NM.017726 Homo sapienε protein phosphata 641
426227 U67058 Hs 154299 (tocuslιnk)NM_005242 Homo sapiens coagul 641
419354 M62839 Hs 1252 NM.000042 Homo sapienε apolipopratem H 627
414987 AA524394 Hs 294022 NM.032865 Homo sapiens hypothetical prot 620
422627 BE336857 Hs 118787 Hs 118787 transforming growth fxtor, be 6 19
407786 AA687538 Hs 38972 NM.005727 Homo εapienε tetraspan 1 (TSPA 6 19
414809 AI434699 Hs 77356 Hs 77356 transferπn rxeptor (p90, CD71 618
425280 U31519 Hs 1872 NM.002591 Homo sapienε phosphoeπolpyruva 6 16
432179 X75208 Hs 2913 NM.004443 Homo sapiens EphB3 (EPHB3), mR 6 16
443957 AA521049 Hs 353013 Hs 353013 chromosome 20 open reading fra 6 15
426174 AA547959 Hs 115838 Hs 115838 ESTs 610
430135 NM.000035 Hs 234234 NM.000035 Homo sapiens aldolase B, fruct 607
420542 NM.000505 Hs 1321 NM.000505 Homo sapiens coagulation fxto 606
409453 AI885516 Hs 95612 Hs 95612 ESTs 606
408482 NM.000676 Hs 45743 NM.000676 Homo sapiens adenosine A2b rx 603
444151 AW972917 Hε 128749 (lxuslιnk)NM_014324 Homo sapiens alpha- 599
444381 BE387335 Hε 283713 NM.138455 Homo sapienε collagen tπple h 597
421408 AI688223 Hs 91096 NM.052816 Homo sapiens tripartite otif- 595
430204 AA618335 Hs 356664 Hε 356664 hypothetical protein FU32334 592
443991 NM 002250 Hs 10082 NM.002250 Homo sapiens potassium interme 590
428874 W32133 Hε 194366 Hs 194366 traπsthyretin (prealbumm, amy 588
408908 BE296227 Hs 250822 (lxuslιπk)NM_003158 Homo εapiens seπne 588
411142 NM.014256 Hs 69009 NM.014256 Homo sapiens UDP-GlcNAc betaGa 586
452281 T93500 Hs 28792 Hs 28792 Homo sapienε cDNA FLJ11041 fis, 582
412115 AK001763 Hε 73239 Hs 73239 hypothetical protein FU 10901 577
421379 Y15221 Hε 103982 NM.005409 Homo sapiens small inducible c 576
433083 AL042759 Hε 191762 Hs 191762 hypothetical protein MGC20258 575
403218 574
412104 AW205197 Hε 240951 (tocuslιnk)NM_033120 Homo sapiens naked 572
449027 AJ271216 Hε 22880 NM.005700 Homo sapiens dipeptidylpeptida 572
429345 R11141 Hs 199695 Hs 199695 hypothetical protein MAC30 572
414753 AF158255 Hs 77225 NM.006437 Homo sapiens ADP-πbosyllransf 572
415000 AW025529 Hs 239812 Hs 239812 serologically defined breast c 571
425206 NM.002153 Hs 155109 NM.002153 Homo sapiens hydroxysteroid (1 570
432978 AF126743 Hs 279884 NM.013238 Homo εapiens DNAJ domain-eonta 570 409889 AW630041 Hs.56937 NM_021978:Homo sapiens suppression of tu 5.67
414052 AW578849 Hs.283552 Hs.283552:hypothetical protein BC016153 5.67
413916 N49813 Hs.75615 NM_000483:Homo sapiens apolipoprotein C- 5.63
418322 AA284166 Hs.84113 NM.005192:Homo sapiens cyclin-dependeπt 5.62
433437 U20536 Hs.3280 NM_001226:Homo sapiens caspase 6, apopto 5.60
424010 AL080188 Hs.137556 NM.033100:Homo sapiens MT-prot∞adherin 5.59
438746 AI885815 Hs.184727 Hs.184727:ESTs, Weakly similar to T45738 5.58
414590 NM 000506 Hs.76530 NM_000506:Homo sapiens coagulation fxto 5.56
457001 J03258 Hs.2062 Hs.2062:vitamin D (1,25- dihydroxyvitami 5.56
423164 AK000232 Hs.124835 NM_019062:Homo εapienε hypothetical prot 5.54
409757 NM 001898 Hs.123114 NM_001898:Homo sapfens cystatin SN (CST1 5.53
425397 J04088 Hs.156346 NM 001067:Homosapien8 topoiεomerase (DN 5.53
403221 5.52
420981 L40904 Hs.100724 NM 005037:Homo εapieπs peroxisome prolif 5.52
417165 R80137 Hs.302738 Hε.302738:Homo sapiens cDNA: FU21425 fi 5.48
419508 AW997938 Hs.90786 NM 003786:Homo sapiens ATP-binding casse 5.44
410850 AW362867 Hs.302738 Hs.302738:Homo sapienε cDNA: FU21425 fi 5.42
436251 BE515065 Hε.296585 (tocuslink)NM_006392:Homo sapiens nucleo 5.41
430603 AA148164 Hε.247280 Hs.247280:chromosome 20 open reading fra 5.36
450505 NM 004572 Hε.25051 NM_004572:Homo sapiens plakophilin 2 (PK 5.34
422535 AA311914 Hs.154578 Hs.154578:Homo εapiens mRNA for FLJ00256 5.33
441384 AA447849 Hs.288660 Hs.288660:Homo sapiens cDNA: FU22182 fi 5.32
425834 NM.001639 Hε.1957 Hs.1957:amyloid P component, serum 5.31
430680 AW138724 Hs.168974 Hs.168974:ESTε 5.25
432378 AI493046 Hs.146133 Hs.146133:ESTs 5.25
419693 AA133749 Hs.301350 Hs.301350:FXYD domain-containing ion tra 5.24
422163 AF027208 Hs.112360 Hs.112360:promiπiπ-like 1 (mouse) 5.21
447320 AI675419 Hs.164464 Hs.164464:Homo sapiens, clone MGC23656 5.21
415927 AL120168 Hs.78919 NM_021083:Homo sapiens Kell blood group 5.21
418203 X54942 Hs.83758 NM_001827:Homo sapienε CDC28 protein kin 5.20
407944 R34008 Hs.239727 NM_024422:Homo sapfens desm∞ollin 2 (DS 5.20
428289 M26301 Hs.2253 Hs.2253:complement component 2 - 5.19
409231 AA446644 Hs.692 NM_002354:Homo sapiens tumor-ass∞iated 5.19
446051 8E048061 Hs.37054 Hε.37054:ephrin-A3 5.15
432269 NM.002447 Hε.2942 Hs.2942:mxrophage stimulating 1 rxepto 5.13
427557 NM.002659 Hs.179657 NM_002659:Homo sapiens plasminogen xtiv 5.11
414639 X67055 Hs.76716 NM_002217:Homo sapiens pre-alpha (globul 5.09
422765 AW409701 Hs.1578 NM_001168:Homo sapiens baculoviral IAP r 5.08
428479 Y00272 Hs.334562 NM_001786:Homo sapiens cell division eye 5.08
425873 NM 013390 Hs.160417 Hs.160417:transmembrane protein 2 5.07
432575 AA553722 Hs.194346 Hs.194346:Spir-2 protein 5.07
409142 AL136877 Hε.50758 Hs.50758:SMC4 structural maintenance of 5.07
427747 AW411425 Hs. 80655 (tocusliπk)NM_004217:Homo sapiens serine 5.06
422609 Z46023 Hs.118721 NM 000434:Homo sapiens sialidase 1 (lyso 5.06
414361 AI086138 Hs.204044 Hs.204044:ESTε 5.04
452940 AA029722 Hs.2173 NM 002033:Homo sapienε fucosyltransferas 5.03
435849 BE305242 Hs.16098 Hs.16098:claudin 2 5.03
411257 AA628967 Hs.115274 Hε.115274:lπdian hedgehog homolog (Draso 5.01
416065 BE267931 Hs.78996 NM_002592:Homo sapiens proliferating eel 5.00
406673 M34996 Hs.198253 Hs.198253:ma]or hiεtocompatibility compl 4.99
451541 BE279383 Hs.26557 NM_007183:Homo sapiens plakophilin 3 (PK 4.99
429833 NM 012079 i Hs.288627 NM.012079:Homo sapiens diacylglycerol 0- 4.98
411393 AW797437 Hs.69771 NM.001710:Homo sapienε B-fxtor, properd 4.98
445109 AF039916 Hε.12330 NM_001247:Homo sapiens xtoπucl∞sidβ tr 4.98
431548 AI834273 Hε.9711 NM_017515:Homo sapiens novel protein (HS 4.97
419574 AK001989 Hs.91165 Hs.91165:hypothetical protein FU11127 4.97
428450 NM.014791 Hs.184339 NM_014791:Homo sapfens maternal embryoni 4.95
431211 M86849 Hs.323733 Hs.323733:gap junction protein, beta 2, 4.95
437009 AF127026 Hs.5394 NM_005379:Homo εapienε myosin IA (MY01 A) 4.93
439453 BE264974 Hs.6566 Hs.6566:thyroid hormone rxeptor interx 4.93
430696 AA531276 Hs.59509 Hε.59509:ESTε, Weakly similar to similar 4.93
431779 AW971178 Hs.268571 (tocuslink)NM_001645:Homo sapiens apolip 4.92
436469 AK001455 Hs.5198 Hs.5198:Down εyndrome critical region ge 4.91
414108 AI267592 Hs.75761 NM_003137:Homo sapiens SFRS protein kina 4.91
422539 AJ009936 Hs.118138 NM_033013:Homo sapienε nuclear rxeptor 4.89
428024 Z29067 Hs.2236 Hs.2236:NIMA (never in mitosis gene a)-r 4.89
428407 NM.003963 Hs.184194 NM_003963:Homo sapiens transmembrane 4 s 4.89
407811 AW190902 Hs.40098 Hs.40098:cysteine knot εuperfamily 1 , BM 4.88
409162 H25530 Hs.50868 Hε.50868:solute earner family 22 (organ 4.88
434370 AF130988 Hs.58346 NM_022336:Homo sapfens xtodysplasin 1, 4.87
413753 U17760 Hs.75517 NM 000228:Homo sapiens laminin, beta 3 ( 4.87
405484 4.87
410639 BE269047 Hs.65234 (lxuslink)NM_017895:Homo sapiens DEAD/H 4.87
428953 AA306610 Hs.348183 NM_003823:Homo sapiens tumor nxrosis fa 4.86
447343 AA256641 Hε.236894 Hs.236894:ESTs, Highly similar to S02392 4.83
421462 AF016495 Hs.104624 NM_020980:Homo sapiens aquaporin 9 (AQP9 4.81
415474 NM 014252 Hε.78457 NM_014252:Homo sapiens εolute cam'erfa 4.79
415099 AI492170 Hs.77917 NM_006002:Homo sapiens ubiquitin carboxy 4.79
417115 AW952792 Hs.334612 NM_003094:Homo sapiens small nuclear rib 4.79
426761 AI015709 Hs.172089 Hs.172089:pro-oncosiε rxeptor inducing 4.78
453751 R36762 Hs.101282 Hε.101282:Homo sapiens mRNA; cDNA DKFZp4 4.77
452721 AJ269529 Hs.301871 Hs.301871 :solute earner family 37 (glyc 4.76
424905 NM.002497 Hs.153704 NM_002497:Homo εapiens NIMA (never in mi 4.76 421943 BE616520 Hs 343912 NM.033504 Homo sapiens CAC-1 (CAC-1), mR 475
400529 475
407233 X16354 Hs 50964 (tocuslιπk)NM_0017l2 Homo sapiens carcin 475
447472 AW207347 Hs 211101 Hs 211101 ESTs 474
447966 AA340605 Hs 105887 (tocuslιnk)NM_145252 Homo sapiens simila 472
439963 AW247529 Hs6793 Hε 6793 platelet activating fxtor xety 472
407103 AA424881 Hε256301 Hs 256301 hypothetical protein MGC13170 470
405556 470
421506 BE302796 Hs 105097 Hs 105097 thymidine kinase 1, soluble 470
444700 NM.003645 Hs 11729 NM.003645 Homo sapiens fatty xid Coenzy 470
443464 BE548446 Hs 321579 NM.021095 Homo sapiens solute carπerfa 470
441623 AA315805 Hs 348710 Hs 348710 Homo sapiens clone IMAGE 4242 470
423068 M25629 Hs 123107 NM.002257 Homo sapiens kallikrein 1, ren 465
422714 AB018335 Hs 119387 NM.014698 Homo sapiens KIAA0792 gene pro 464
403739 461
427490 Z95152 Hs 178695 NM.002754 Homo sapiens mitogen activated 461
426088 AF038007 Hs 166196 NM.005603 Homo sapiens ATPase, Class I, 461
412723 AA648459 Hs 335951 Hs 335951 hypothetical protein AF301222 460
424825 AF207069 Hs 153357 NM.001084 Homo sapiens procollagen lysm 460
447335 BE617695 Hs 286192 NM.032192 Homo sapiens protein phosphata 459
424441 X14850 Hs 147097 Hs 147097 H2A histone family member X 459
432150 AK000224 Hs 272789 NM.017716 Homo sapiens membrane-spanning 459
414695 BE439915 Hs76913 Hs 76913 proteasome (prosome mxropain) 459
450737 AW007152 Hs 63325 Hs 63325 transmembrane protease, senne 458
435327 BE301871 Hε 4867 Hs 4867 mannosyl (alpha 1,3-)-glycoprote 457
411263 BE297802 Hs 69360 NM.006845 Homo sapiens kmesm like 6 (m 457
408056 AA312329 Hs42331 Hs42331 ephπn A4 455
409964 AW368226 Hs 67928 Hs 67928 ESTs 454
417576 AA339449 Hs 82285 NM.000818 Homo sapiens phosphoπbosylgly 454
432407 AA221036 AF134164 Homo sapiens Human endogenous r 454
439975 AW328081 Hs6817 NM.033453 Homo sapiens inosine tπphosph 453
409213 U61412 Hs 51133 NM.005975 Homo sapiens PTK6 protein tyro 453
403219 453
412974 R18978 Hs 75105 NM.006579 Homo sapiens emopamil binding 452
408194 AA601038 Hs 191797 Hs 191797 ESTs 452
422237 M13149 Hs 1498 NM.000412 Homo sapiens histidiπe-πch gl 451
456906 AF117646 Hs 156637 NM.012116 Homo sapiens Cas Br-M ( unne) 51
425123 AW205274 Hs 154695 NM.000303 Homo sapiens phosphomannomutas 451
425743 BE396495 Hs 159428 NM.138761 Homo sapiens BCL2-assxιated X 450
406684 X16354 Hs 50964 (locuslιπk)NM_001712 Homo sapiens carcin 450
439580 AF086401 Hs 293847 Hs 293847 ESTs 450
411126 NM.001202 Hs68879 (lMuslιnk)NM_001202 Homo sapiens bone m 449
428385 AF112213 Hs 184062 Hs 184062 chromosome 20 open reading fra 448
434263 N34895 Hs 79187 Hs 79187 coxsxkie virus and adenovirus 447
431945 AW000827 Hs 11962 NM.030766 Homo sapiens apoptosis regulat 447
422616 BE300330 Hs 118725 NM.012248 Homo sapiens selenophosphate s 446
452299 AW206330 Hs355663 Hs 355663 ESTε 446
414998 NM.002543 Hε77729 NM.002543 Homo sapiens oxidised low dens 446
452888 AW955454 Hs 30942 NM.004093 Homo sapiens ephπn B2 (EFNB2) 446
442013 AA506476 Hs 375009 Hs 375009 Homo sapiens mRNA, cDNA DKFZpβ 446
450334 AF035959 Hs 24879 Hs 24879 phosphatidic xid phosphatase t 445
445417 AK001058 Hs 12680 Hs 12680 Homo sapiens cDNA FU10196 (is, 444
433662 W07162 Hε 150826 NM.020387 Homo sapiens RAB25, member RAS 444
419559 Y07828 Hs 91096 NM.007028 Homo sapiens tripartite motif- 444
425860 L29339 Hs1964 NM.000343 Homo sapiens solute earner fa 443
408847 AW290997 Hs 190153 Hs 190153 Homo sapiens cDNA FU33988 fis 443
431836 AF178532 Hs 271411 NM.138992 Homo sapiens beta-site APP-cle 443
435777 AW419202 Hs 286192 NM.032192 Homo sapiens protein phosphata 442
422867 L32137 Hs1584 Hs 1584 cartilage oligomeπc matnx prot 441
431350 AI192528 Hs 164537 Hs 164537 ESTs 439
432593 AW301003 Hs 51483 Hs 51483 Homo sapienε Similarto RIKEN 439
421975 AW961017 Hs 6459 (locuslιnk)NM_024531 Homo sapiens hypoth 439
412870 N22788 Hs82407 NM.022059 Homo sapiens chemokine (C-X-C 438
412133 U83460 Hs 104557 NM.001859 Homo sapiens solute earner fa 438
422293 X94453 Hs 114366 Hs 114366 pyrrolιπe-5-carboxylate synthe 438
425998 AU076629 Hs 165950 NM.002011 Homo sapiens fibroblast growth 438
453082 H18835 Hs 31608 (locuslιnk)NM_017636 Homo sapiens transi 437
453111 AB014598 Hs 31720 NM.014799 Homo sapiens hephaestm (HEPH) 436
432677 NM.004482 Hs 278611 NM.004482 Homo sapiens UDP-N acetyl alph 436
429271 AF039850 Hs 198515 NM.005224 Homo sapiens dead πnger like 435
426108 AA622037 Hs 166468 NM.004708 Homo sapiens programmed cell d 434
412612 NM.000047 Hs 74131 NM.000047 Homo sapiens arylsulfatase E ( 434
424865 AF011333 Hs 153563 NM.002349 Homo sapiens lymphxyte antige 434
427239 BE270447 Hs 356512 Hs 356512 ESTs Weakly similar to UBCA.A 433
413254 U40272 Hs75253 NM.004135 Homo sapiens isocitrate dehydr 432
439659 AW970780 Hs 59483 Hε 59483 leucine-nch repeat-containing 432
417526 AA568906 Hs 82240 Hε 82240 εyπtaxιn 3A 432
413186 AU077141 Hs 374548 Hs 374548 solute earner family 16 (mono 431
436391 AJ227892 Hs 146274 Hs 146274 ESTs 430
413219 AA878200 Hs 118727 Hs 118727 Homo sapiens cDNA FU33803 fis 429
452017 AF109302 Hs 27495 Hs 27495 prostate cancer associated prot 429
408113 T82427 Hs 194101 Hs 194101 Homo sapiens cDNA FU20869 fi 429
429638 AI916662 Hs211577 (locuslιnk)NM_004986 Homo sapienε kmxt 429 432636 AA340864 Hs 278562 NM.001307 Homo sapiens claudin 7 (CLDN7) 429
412869 AA290712 Hs 82407 Hs 82407 chemokine (C-X C motif) ligand 429
443638 BE269042 Hs9661 Hs 9661 proteasome (proεo e, mxropain) 428
418245 AA088767 Hs 83883 NM.020182 Homo sapiens transmembrane pr 427
409636 AA305729 Hs 18272 (tocuslιnk)NM 030674 Homo sapiens solute 427
408989 AW361666 Hs49500 Hs 49500 KIAA0746 protein 427
428023 AL038843 Hs 374530 Hs 374530 Homo sapiens cDNA FU23602 fi 427
410199 AW377424 Hs 205126 Hs 205126 Homo sapiens cDNA FU22667 fi 424
431685 AW296135 Hs 267659 NM.006113 Homo sapiens vav 3 oncogene (V 424
409956 AW103364 Hs727 NM 02192 Homo sapiens inhibin, beta A ( 424
413278 BE563085 Hs833 Hs 833 interferon stimulated protein, 15 423
431193 AW749505 Hε 296770 Hs 296770 KIAA1719 protein 423
436856 AI469355 Hε 127310 (tocuslιπk)NM_144624 Homo sapiens kinase 423
456629 AW891965 Hs 367942 Hε 367942 Homo sapiens, clone IMAGE 4701 423
426682 AV660038 Hs 2056 Hs 2056 UDP glycosyltransferase 1 family 423
418054 NM 002318 Hs 83354 NM.002318 Homo sapiens lysyl oxidase-lik 422
418526 BE019020 Hs 85838 NM.004207 Homo sapiens solute earner fa 422
437897 AA770561 Hs 146170 Hs 146170 hypothetical protein FU22969 421
435099 AC004770 Hs4756 NM.004111 Homo sapιens flap8tructure-sp 421
419378 R24922 Hε 90078 Hs 90078 nucleotide sugar transporter si 421
421585 U95626 Hs 302043 NM.003965 Homo sapienε chemokine (C-C mo 420
420039 NM.004605 Hs376147 Hs 376147 Homo sapienε cDNA FU39099 fiε 420
426427 M86699 Hs 169840 Hs 169840 TTK protein kinase 4 19
425263 NM.001197 Hs 155419 NM.001197 Homo sapiens BCL2 interacting 419
426031 AA295251 Hs 166066 (tocuslinkJNM 006697 Homo εapienε ciεpla 419
441085 AW136551 Hs 181245 Hs 181245 Homo sapienε cDNA FU12532 fiε 4 19
412939 AW411491 Hε 75069 Hε 75069 seπne fiydroxymethyltransferase 418
430514 AA318501 Hs 241587 NM.021246 Homo sapiens lymphxyte antige 417
431842 NM.005764 Hε 271473 Hs 271473 epithelial protein up-regulate 417
430387 AW372884 Hs 240770 Hs 240770 nuclear cap binding protein su 4 17
404826 4 17
414198 AW505308 Hs 75812 NM.004563 Homo sapiens phosphoeπolpyruva 4 17
434203 BE262677 Hs 283558 NM 018509 Homo sapiens hypothetical prot 4 17
426378 U80082 Hs 169600 Hs 169600 KIAA0826 protein 4 16
433020 AI375726 Hs 227152 NM.016391 Homo sapiens hypothetical prot 4 16
420319 AW406289 Hs 96593 NM.019034 Homo sapienε ras homolog gene 4 15
446696 AF279265 Hs 298476 NM.022911 Homo sapiens solute earner fa 4 15
400130 Hs 155560 NM.001746 Homo sapienε calπexin (CANX) 414
431890 X17033 Hs 271986 NM.002203 Homo εapieπs integπn, alpha 2 414
425003 AF119046 Hs 154149 NM.014481 Homo εapieπs APEX nuclease (ap 4 13
417386 AL037228 Hs 301957 NM.018144 Homo sapiens Sx61 alpha form 413
424837 BE276113 Hε 333034 NM 003491 Homo sapiens ARD1 homolog, N a 4 13
424534 D87682 Hε 150275 Hs 160275 KIAA0241 protein 413
445462 AA378776 Hε 288649 (tocuslιnk)NM_024051 Homo sapiens hypoth 412
428471 X57348 Hs 184510 Hs 184510 stratifin 412
409012 AL117435 Hs49725 Hs 49725 DKFZP434I216 protein 4 11
424154 AF026004 Hs 141660 NM.004366 Homo εapienε chloπde channel 410
400290 H18836 Hs 31608 (tocuslιnk)NM_017636 Homo sapiens transi 410
409152 AA176585 Hs 194346 Hs 194346 Spιr-2 protein 410
427333 AF067797 Hs 176658 NM.001169 Homo sapiens aquapoπn 8 (AQP8 410
413835 AI272727 Hs 249163 NM.024306 Homo sapiens fatty xid hydrox 409
444664 N26362 Hs 11615 NM.016086 Homo sapienε map kinase phosph 409
421959 AW751497 Hs 98370 NM.030622 Homo sapiens cytochrome P450, 409
407777 AA161071 Hs 71465 Hs 71465 squalene epoxidase 409
414806 D14694 Hs 77329 (lxuslιnk)NM_014754 Homo sapiens phosph 408
421190 U95031 Hs 102482 Hs 102482 mucιn 5, subtype B, tracheobro 408
408683 R58665 Hs 46847 NM.016614 Homo sapiens TRAF and TNF rxe 408
419488 AA316241 Hs 90691 NM.006993 Homo sapiens nucleophosmin/nuc 406
414907 X90725 Hs 77597 NM.O0O998 Homo sapiens πbosomal protein 406
425247 NM.00594C 1 Hs 155324 Hs 155324 matrix metalloprotemase 11 (s 406
443802 AW504924 Hs9805 Hs 9805exportιn 5 404
411165 NM.00016S I Hs 69089 NM.000169 Homo sapiens galxtosidase, al 404
434808 AF155108 Hs256150 Hs 256150 NY-REN41 antigen 404
428376 AF119665 Hs 184011 Hs 184011 pyrophosphatase (inorganic) 404
418216 AA662240 Hs 283099 Hs 283099 AF15q14 protein 402
436278 BE396290 Hs5097 Hs 5097syπaptogynn 2 402
421910 NM.014586 Hs 109437 NM.014586 Homo sapiens hormonally upregu 402
417866 AW067903 Hs 82772 Hs 82772 collagen, type XI, alpha 1 402
449057 AB037784 Hs 22941 Hs 22941 KIAA1363 protein 401
414561 AI064813 Hs 195155 Hs 195155 solute camerfamily 38, memb 400
414812 X72755 Hs 77367 NM.002416 Homo sapienε monokine induced 400
456362 AW973003 Hs 179909 (tocuslιπk)NM_024831 Homo sapiens nuclea 399
431958 X63629 Hs 2877 NM.001793 Homo sapienε cadhenn 3, type 398
418661 NM.001949 Hs1189 NM.001949 Homo sapiens E2F transcnption 398
419092 J05581 Hs 89603 NM.002456 Homo sapiens mucin 1, transmem 398
414013 AA766605 Hs 47099 NM.024642 Homo sapiens hypothetical prot 398
409093 BE243834 Hs 50441 NM.015936 Homo sapiens CGI 04 protein (L 397
445873 AA250970 Hs 251946 Hs 251946 Homo sapiens cDNA FU11840 fis 396
436485 X59135 Hs 156110 Hs 156110 immunoglobulin kappa constant 396
422164 NM.014312 Hs 112377 Hs 112377 cortical thym∞yte rxeptor (X 395
437016 AU076916 Hs5398 Hs 5398 guanine monphosphate synthetase 394
449437 AI702038 Hε 100057 Hs 100057 senne/threoπine kinase 35 394
446946 AI878932 Hs317 NM.003286 Homo sapiens topoisomerase (DN 394 420162 BE378432 Hs.95577 NM_052984:Homo sapienε cycliπ-dependent 3.94
443180 R15875 Hs.258576 NM_012129:Homo sapiens claudin 12 (CLDN1 3.93
418738 AW388633 Hs.6682 Hs.6682:solute carrier family 7, (cation 3.93
409463 AI458165 Hs.17296 NM_023930:Homo sapiens hypothetical prat 3.92
447495 AW401864 Hs.18720 NM_004208:Homo sapiens programmed cell d 3.92
448093 AW977382 Hs.15898 Hs.15898:2,4-dienoyl CoA reductase 2, pe 3.91
428698 AA852773 Hs.334838 Hs.334838:KIAA1866 protein 3.90
438485 W57578 Hs.378718 Hs.378718:Homo sapiens cDNA FU33433 fis 3.89
436827 H72187 Hs.356668 (tocusliπk)NM_005274:Homo sapiens guanin 3.89
407971 AI469117 Hs.62918 Hs.62918:CDC91 cell division cycle 91-11 3.89
400750 3.89
448140 AF146761 Hs.20450 NM.020125:Homo sapiens B lymph∞yte xti 3.89
413880 AI660842 Hs.110915 NM.021258:Homo sapiens interleukin 22 re 3.89
453258 AW293134 Hs.32597 NM_005977:Homo sapiens ring finger prate 3.89
428788 AF082283 Hs.193516 NM.003921 :Homo sapiens B-cell CLUIympho 3.88
443044 N28522 Hs.8935 NM.014298:Homo sapiens quiπoliπate phosp 3.88
413095 AA494359 Hs.30715 Hs.30715:potassium voltage-gated channel 3.88
417129 AI381800 Hs.300684 Hε.300684:calcitonin gene-related peptid 3.87
410268 AA316181 Hs.61635 NM.012449:Homo εapienε six transmembrane 3.87
425047 U34038 Hs.154299 NM_005242:Homo sapiens coagulation fxto 3.87
416084 L16991 Hs.79006 NM 012145:Homo sapiens deoxythymidylate 3.86
449667 AB023227 Hs.23860 Hs.23860:KIAA1010 protein 3.86
400298 AA032279 Hs.61635 Hs.61635:six transmembrane epithelial an 3.85
407770 AW607831 Hs.38738 NM_014343:Homo sapienε claudin 15 (CLDN1 3.85
418313 BE244231 Hs.84038 NM.015937:Homo εapiens CGI-06 protein (L 3.85
413380 AI904232 Hs.75323 Hs.75323:prohibitin 3.85
452220 BE158006 Hε.212296 Hε.212296:ESTs 3.85
413588 AA971014 Hs.75432 NM_000884:Homo sapienε IMP (inosine mono 3.85
433658 L03678 Hs.156110 Hs.156110:immunoglobulin kappa constant 3.84
428474 AB023182 Hs.184523 Hs.184523:serine/thr∞πine kinase 38 lik 3.84
430237 AI272144 Hs.236522 Hs.236522:DKFZP434P106 protein 3.84
414862 BE621310 Hs.923 Hs.923:single-stranded DNA binding prate 3.84
437967 BE277414 Hs.5947 NM_005370:Homo sapiens mel transforming 3.84
427318 AF186081 Hs.175783 NM 014579:Homo sapienε solute carrier fa 3.83
459306 AW578452 AW578452:RC1-CT0252-030100-023-b07 CT025 3.83
446342 BE298665 Hs.14846 Hs.14846:Homo sapiens mRNA; cDNA DKFZp56 3.83
432886 BE159028 Hs.279704 Hs.279704:chromatin accessibility comple 3.82
434845 BE267057 Hs.325321 Hs.325321:WD repeat domain 18 3.82
426514 BE616633 Hs.170195 Hε.170195:bone morphcgeπetic protein 7 ( 3.82
410315 AI638871 Hε.378965 Hε.378965:Homo sapiens cDNA FU37658 fis 3.82
421905 AI660247 Hs.32699 Hs.32699:Homo sapienε, Similar to RIKEN 3.81
421481 AW391972 Hs.104696 Hε.104696:KIAA1324 protein 3.81
445921 AW015211 Hs.153799 Hs.153799:Homo sapiens cDNA FU38333 fis 3.80
414368 W70171 Hs.75939 NM_012474:Homo sapiens uridine monophosp 3.80
457284 AF102850 Hs.227933 NM.013338:Homo εapienε Alg5, S. cerevisi 3.80
413813 M96956 Hs.75561 NM_003212:Homo sapiens teratocarcinoma-d 3.80
414602 AW630088 Hε.76550 NM 052886:Homo εapienε mal, T-cell diffe 3.80
410219 T98226 Hs.171952 Hs.171952:∞cludin 3.80
407137 T97307 3.78
430462 AI584156 Hs.105640 Hs.105640:hypothetical protein BC007772 3.78
432680 T47364 Hs.278613 (l∞uslink)NM_005532:Homo εapienε interf 3.78
450010 AW293801 Hs.255052 Hε.255052:ESTε 3.78
440334 BE276112 Hs.7165 NM_003904:Homo εapiens zinc finger prate 3.78
440676 NM 004987 ' Hs.112378 (locuslink)NM_004987:Homo εapienε UM an 3.77
428072 BE258602 Hs.182366 NM_016292:Homo sapiens heat shxk protei 3.77
407722 BE252241 Hs.38041 NM.003681 :Homo εapieπs pyridoxal (pyrido 3.77
426459 AF151812 Hε.169992 NM_015966:Homo sapiens serologically def 3.77
443323 BE560621 Hs.9222 Hs.9222:estrogen receptor binding site a 3.76
406621 X57809 Hs.181125 Hs.181125:immunoglobulin lambda Ixuε 3.76
423198 M81933 Hε.1634 Hs.1634:cell division cycle 25A 3.76
428206 AB020643 Hs.183006 Hs.183006:likely homolog of mouse hepari 3.75
447200 BE543146 Hs.281434 Hs.281434:Homo sapienε cDNA FU31373 fiε 3.74
425209 AL049761 Hε.155140 NM_001895:Homo εapieπs casein kinase 2, 3.74
411950 T28407 Hs.81564 NM_002619:Homo sapienε plateletfxtor 4 3.74
418681 AA287786 Hs.23449 Hs.23449:insuliπ rxeptor tyrosine kinas 3.74
421532 AW138207 Hs.146170 NM_022842:Homo sapienε hypothetical prat 3.74
446291 BE397753 Hs.14623 Hε.14623:interferoπ, gamma-inducible pro 3.74
435886 BE265839 Hs.12126 NM.018487:Homo sapiens hepatxellular ca 3.73
417286 AA122237 Hs.81874 NM_002413:Homo sapiens microso al glutat 3.73
421743 T35958 Hs.107614 Hs.107614:DKFZP564I1171 protein 3.73
400419 AF084545 AF084545:Homo sapiens versican Vint iεof 3.73
421357 AK000609 Hs.103808 NM_017896:Homo sapiens chromosome 20 ope 3.73
420665 AW469240 Hs.371581 Hs.371581:ESTs 3.73
418703 NM.014448 Hs.87435 Hs.87435:Rho guanine exchange fxtor (GE 3.73
452679 Z42387 Hs.83883 (l∞uslink)NM_020182:Homo εapienε transm 3.72
419743 AW408762 Hs.5957 Hs.5957:Homo sapiens clone 24416 mRNA se 3.72
435730 AB020635 Hs.4984 Hs.4984:KIAA0828 protein 3.72
431512 BE270734 Hs.2795 Hs.2795:lxtate dehydrogenase A 3.72
444006 BE395085 Hs.334762 (tocuslink)NM_032832:Homo sapiens hypoth 3.72
442875 BE623003 Hε.23625 Hs.23625:Homo sapiens clone TCCCTA00142 3.71
413431 AW246428 Hs.75355 NM_003348:Homo sapienε ubiquitin-conjuga 3.71
413950 AA249096 Hs.32793 Hε.32793:Homo sapiens cDNA FU31108 fis, 3.71
411125 AA151647 Hε.68877 Hs.68877:cytochrome b-245, alpha polypep 3.71 406722 H27498 Hs.293441 Hs.293441 :Homo sapiens SNC73 protein (SN 3.71
418416 U11700 Hs.84999 NM_000053:Homo sapiens ATPase, Cu++ traπ 3.71
421038 AL080192 Hs.101282 Hs.101282:Homo sapfens mRNA; cDNA DKFZp4 3.70
409327 L41162 Hs.53563 NM_001853:Homo sapiens collagen, type IX 3.70
413476 U25849 Hs.75393 NM_004300:Homo sapiens xid phosphatase 3.70
400846 3.70
415003 M11437 Hε.77741 Hs.77741:kininogen 3.70
408137 AI694131 Hs.29002 Hs.29002:KIAA1706 protein 3.70
418650 BE386750 Hs.86978 Hε.86978:prolyl endopeptidase 3.70
413179 N99692 Hs.75227 NM_005002:Homo sapiens NADH dehydrogenas 3.69
425843 BE313280 Hs.159627 NM_004632:Homo sapiens death ass∞iated 3.69
432215 AU076609 Hs.2934 NM_001033:Homo εapienε ribonucleotide re 3.69
413781 J05272 Hs.850 (tocuslink)NM_000883:Homo sapiens IMP (i 3.69
429344 R94038 Hs.374664 NM_005538:Homo sapienε inhibin, beta C ( 3.69
442315 AA173992 Hs.7956 Hε.7956:ESTε 3.68
452875 BE275760 Hs.30928 NM_006114:Homo sapfens translocase of ou 3.68
401179 3.67
410174 AA306007 Hs.59461 Hs.59461:DKFZP434C245 protein 3.67
418558 AW082266 Hs.86131 Hs.86131:Fas (TNFRSF6)-ass∞iated via de 3.67
440086 NM.005402 Hs.6906 NM_005402:Homo sapiens v-ral simian leuk 3.66
409402 AF208234 Hs.695 Hs.695:cystatin B (stefin B) 3.66
436014 AF281134 Hs.283741 NM_020158:Homo sapiens exosome component 3.66
432633 AI796390 Hs.210667 Hs.210667:ESTs 3.66
412599 AU076782 Hs.248267 (locusliπk)NM_021126:Homo sapiens mercap 3.66
453857 AL080235 Hs.35861 Hs.35861 :Ras-iπduced seneεcence 1 3.65
432211 BE274530 Hs.273333 Hs.273333:hypothetical protein FLJ10986 3.65
430720 U85768 Hs.247838 NM_002991:Homo sapiens small inducible c 3.65
432320 AW411066 Hs.274351 NM_016032:Homo sapienε zinc finger, DHHC 3.64
420186 NM 015925 Hs.95697 Hs.95697:liver-spxific bHLH-Zip tranεcr 3.64
441128 AA570256 Hs.348504 Hε.348504:hypofhetical protein BC014072 3.64
444184 T87841 Hs.282990 (locusliπk)NM_033550:Homo sapiens chromo 3.64
411678 AI907114 Hs.71465 NM_003129:Homo sapiens squalene epoxidas 3.63
423750 AF165883 Hs.298229 NM_012394:Homo sapfens prefoldin 2 (PFDN 3.62
412948 BE243313 Hs.334851 Hs.334851:LI and SH3 protein 1 3.62
452098 AI858183 BF755039:QV0-CT0583-181000-428-f07 CT058 3.62
430024 AI808780 Hs.227730 NM.000210:Homo sapiens integnn, alpha 6 3.62
416412 NM 014742 Hs.79305 Hs.79305:KIAA0255 gene product 3.61
437712 X04588 Hs.85844 Hs.85844:neurotraphio tyrosine kinase, r 3.61
400847 3.60
406671 AA129547 Hs.285754 NM_000245:Homo sapiens met proto-oπcogen 3.60
412641 M16660 Hs.74335 Hs.74335:heat shxk 90kD protein 1, beta 3.60
404854 3.60
400448 3.60
453331 AI240665 Hs.352537 Hε.352537:Homo sapiens cDNA FU31066 fis 3.60
441406 Z45957 Hs.7837 Hs.7837:phosphoρrotein regulated by mito 3.60
417389 BE260964 Hs.82045 Hs.82045:midkine (πeurite growth-promoti 3.59
419607 R52557 Hs.91579 NM_033416:Homo sapiens similarto HYPOTH 3.59
447250 AI878909 Hs.17883 NM_002707:Homo sapiens protein phosphata 3.59
446356 AI816736 Hs.14896 Hs.14896:zinc finger, DHHC domain contai 3.59
431236 AV656840 Hs.285115 NM_001560:Homo εapiens interleukin 13 re 3.59
426722 U53823 Hs.171952 NM_002538:Homo sapiens o∞ludin (OCLN), 3.58
420531 AI652069 Hs.98614 NM_004587:Homo sapiens ribosome binding 3.58
416933 BE561850 Hs.80506 NM_003090:Homo sapiens small nuclear rib 3.57
447698 AI420156 Hs.326733 NM_052858:Homo sapiens similar to RIKEN 3.57
434457 AF141332 Hs.200333 NM.018690:Homo sapiens apolipoprotein B4 3.57
424241 AW995948 Hs.8364 Hs.8364:pyruvate dehydrogenase kinase, i 3.57
452264 AU077013 Hε.28757 Hs.28757:transmembrane 9 superfamily mem 3.57
420614 AL110291 Hs.99364 Hs.99364:abhydrolaεe domain containing 1 3.56
434224 AA380731 Hs.84 NM_000206:Homo sapiens interleukin 2 rx 3.56
425322 U63630 Hs.155637 NM_006904:Homo sapiens protein kinase, D 3.56
438407 AI457122 Hs.129673 Hs.129673:eukaryotic translation initiat 3.56
413859 AW992356 Hs.8364 Hs.8364:pyruvate dehydrogenase kinase, i 3.56
427268 X78520 Hε.174139 NM.001829:Homo sapiens chloride channel 3.55
436127 W94824 Hs.11565 NM_080748:Homo sapiens chromosome 20 ope 3.55
411704 AI499220 Hs.71573 (lxuslink)NM_017988:Homo sapiens hypoth 3.55
452700 AI859390 Hs.288940 NM_021259:Homo sapiens transmembrane pro 3.54
418803 U50079 Hs.88556 NM_004964:Homo sapfens histone dexetyla 3.54
453323 AF034102 Hs.32951 NM.001532:Homo sapiens solute earner fa 3.54
422813 AV656571 Hs.121068 (lxuslink)NM_003270:Homo sapiens transm 3.54
452488 N74921 Hs.184389 Hs.184389:ESTs, Moderately εimilar to S1 3.54
432268 BE311856 Hs.274230 Hs.274230:3'-phosphoadenoεine 5'-phospho 3.54
425811 AL039104 Hs.159557 NM_002266:Homo sapiens karyopheriπ alpha 3.53
437741 BE561610 Hs.5809 NM_020470:Homo sapienε putative tranεmem 3.53
421802 BE261458 Hs.108408 (lxuslink)NM_016022:Homo sapiens CGI-78 3.53
428582 BE336699 Hs.185055 Hs.185055:BENE protein 3.53
446147 AL133064 Hs.14051 (l∞uslink)NM_145698:Homo sapiens eπdoze 3.53
408716 AI567839 Hs.151714 (tocuslink)NM_033405:Homo sapfens peroxi 3.52
450825 AC005954 Hs.25527 (tocuslink)NM_014428:Homo sapiens tight 3.52
442007 AA301116 Hs.142838 NM_032390:Homo sapiens MKI67 (FHA domain 3.52
453454 AW052006i Hs.374973 NM_004697:Homo sapiens PRP4 pre-mRNA pro 3.52
421612 AF161254 Hs.106196 (l∞uslink)NM_016579:Homo sapiens 8D6 an 3.51
428371 AB012193 Hs.183874 NM_003589:Homo sapiens cullin 4A (CUL4A) 3.51
421340 F07783 Hε.1369 NM_000574:Homo sapiens dxay acceleratin 3.50 429023 NM 000312 Hε2351 NM 000312 Homo sapiens protein C (inxti 350
452862 AW378065 Hs 8687 Hs 8687 ESTs 350
442993 BE018682 Hs 166196 Hs 166196 ATPase, Class I, type 8B memb 350
404240 350
424909 S78187 Hs 153752 (focuslιnk)NM_004358 Homo sapiens cell d 350
429583 NM 006412 Hs 209119 NM.006412 Homo εapiens 1-xylglyceral 3- 350
445937 AI452943 Hs 321231 (lxuslιnk)NM_003779 Homo sapiens UDP-Ga 349
424954 NM 000546 Hs 1846 NM.000546 Homo sapiens tumor protein p53 349
424142 AI678727 Hs 378970 Hs 378970 Homo sapiens cDNA FU35102 fis 349
428028 U52112 Hs 182018 Hs 182018 ιnterteukιπ-1 rxeptor-ass∞ia 349
456534 X91195 Hs 100623 NM.138689 Homo sapiens protein phosphata 349
424685 W21223 Hs 151734 Hs 151734 nuclear traπεport fxtor 2 349
419170 BE002798 Hs 287850 NM.002219 Homo εapieπs integral membrane 349
439841 AF038961 Hs6710 NM.004870 Homo sapiens mannose P-dolicho 349
428390 AI640377 Hs 350077 NM.000982 Homo εapienε πbosomal protein 348
430589 AJ002744 Hs 246315 NM.017423 Homo sapiens UDP-N xetyl alph 348
431183 NM 006855 Hs 250696 NM.006855 Homo sapiens KDEL (Lys Asp-Glu 348
422599 BE387202 Hs 118638 Hs 118638 non metastatic cells 1, protei 348
457635 AV660976 Hs 3569 Hs 3569 chromosome 20 open reading frame 348
419705 AW368634 Hs 154331 Hs 154331 ESTs 348
454390 AB020713 Hs 56966 (tocuslιnk)NM_024923 Homo sapiens hypoth 348
402829 347
451707 AW051061 Hs 60973 Hs 60973 Homo sapiens cDNA FU40829 fis, 347
433604 NM 013442 Hs3439 Hs 3439 stomalιn (EPB72) lιke 2 347
420085 AI741909 Hs 44680 Hs 44680 hypothetical protein FU20979 347
437704 AA766142 Hs 131810 Hs 131810 Homo sapiens cDNA FU35976 fis 347
439223 AW238299 Hs 250618 NM.025217 Homo εapienε UL16 binding prot 346
452203 X57522 Hs 352018 NM.000593 Homo sapiens transporter 1, AT 346
450273 AW296454 Hs 24743 Hs 24743 hypothetical protein FLJ20171 346
408089 H59799 Hs42644 Hs 42644 thioredoxm like 2 346
446950 AA305800 Hs5672 (focuslιπk)NM_030799 Homo sapiens golgi 346
437379 AL359575 Hs 23765 Hs 23765 membrane metallo-βndopeptidase- 345
427581 NM 014788 Hs 179703 NM.014788 Homo sapiens tripartite motf- 345
433627 AF078866 Hs 284296 NM.033161 Homo sapiens surfeit 4 (SURF4) 345
400263 Hs 75309 NM.001961 Homo sapienε eukaryotic transi 345
433570 AI580053 Hs 109007 Hs 109007 Homo sapiens, Similar to LOC16 345
410636 AA088177 Hs 172870 Hs 172870 KIAA1913 protein 345
456950 AF111170 Hs 306165 Hs 306165 ESTs, Highly similar to unknow 344
432391 AI732374 Hs 339827 Hs 339827 ESTs, Weakly similar to protea 344
428144 BE269243 Hs 182625 Hs 182625 VAMP (veεicle-assxiated membr 344
417144 AA382104 Hs 81337 Hs 81337 Ixtin, galactoside-b ding so 344
458778 AW451034 Hs 326525 NM.001669 Homo sapienε arylsulfatase D ( 344
425274 BE281191 Hs155462 Hs 155462 MCM6 minichromosome maintenanc 344
448913 AA194422 Hs 22564 NM.004999 Homo sapienε myosin VI (MY06), 344
448847 AI587180 Hs 110906 Hs 110906 hypothetical protein BC004501 344
420166 AW732276 Hs 95583 NM.012339 Homo sapienε transmembrane 4 s 344
412420 AL035668 Hs73853 NM.001200 Homo sapiens bone morphogeneti 343
424482 BE268621 Hs 149155 (lxuslιnk)NM_003374 Homo sapiens voltag 343
414186 U33446 Hs75799 Hs 75799 protease, seπne, 8 (prostasin) 343
422396 W21872 Hs7907 (lxuslιnk)NM_145059 Homo sapiens L-fuco 343
428093 AW594506 Hs 104830 Hs 104830 ESTε 343
428293 BE250944 Hs 183556 Hε 183556 solute earner family 1 (neutr 342
445580 AF167572 Hs 12912 NM.006109 Homo sapiens SKB1 homolog (S 342
442821 BE391929 Hs8752 Hs 8752 transmembrane protein 4 342
427597 D15049 Hs 179770 NM.002842 Homo sapiens protein tyrosine 342
427648 AI376722 Hs 180062 Hs 180062 proteasome (prosome, mxropain 341
428734 BE303044 Hs 192023 NM.003757 Homo sapiens eukaryotic transi 341
453902 BE502341 Hs3402 NM.139177 Homo sapiens chromosome 17 ope 341
441565 AW953575 Hs 303125 Hs 303125 p53-ιnduced protein PIGPC1 341
414045 NM 002951 I Hs75722 NM.002951 Homo εapienε nbophonn II (RP 341
423323 AI951628 Hs 127007 NM.003740 Homo sapiens potassium channel 341
443303 U67319 Hs9216 NM.033340 Homo sapiens caspase 7, apopto 341
426268 AF083420 Hs 168913 NM.003576 Homo sapiens seπne threoπlne 340
422256 M64673 Hs 1499 NM.005526 Homo sapiens heat shock transc 340
451129 BE072881 BE072881 RC2-BT0548-200300-012 e09 BT054 340
400205 Hs 81848 NM.006265 Homo sapiens RAD21 homolog (S 340
428109 AW732918 Hs 182490 Hs 182490 leucme-πch PPR-motrf contain 339
448440 AA173467 Hs62402 Hs 62402 p21/Cdc42/Rx1-xuvated kinase 339
426858 NM 004182 Hs 172791 NM.004182 Homo sapiens ubiquitously-expr 339
417457 AA378907 Hs349326 Hs 349326 Homo sapiens cDNA FU30677fis 339
406363 339
444758 AL044878 Hs 11899 NM.000859 Homo εapisns 3-hydroxy-3-methy 339
423309 BE006775 Hs 126782 NM.014467 Homo sapiens sushi-repeat prot 338
426125 X87241 Hs 166994 Hs 166994 FAT tumor suppressor homolog 1 338
452835 AK001269 Hs30738 NM.018087 Homo sapiens hypothetical prot 338
419493 AF001212 Hs 90744 Hs 90744 proteasome (prosome, mxropain) 338
457670 AF119666 Hs 23449 NM.018842 Homo sapiens insulin receptor 338
400125 Hε 125078 (focustιnk)NM_004152 Homo εapiens omith 338
429404 NM 005738 Hs 10706 NM.005738 Homo sapienε ADP-πbosylation 337
410293 AK000047 Hs 61960 NM.018892 Homo sapienε hypothetical prot 337
434826 AF155661 Hs 22265 Hs 22265 pyruvate dehydrogenase phosphat 337
423599 AI805664 Hs31731 (lxuεlιnk)NM_012094 Homo sapiens peroxi 337
427715 BE245274 Hs 180428 Hs 180428 KIAA1181 protein 337 446715 AI337735 Hs 173919 Hs 173919 ESTs Weakly similar to neuron 336
426788 U66615 Hs 172280 NM.003074 Homo sapiens SWI/SNF related, 336
429747 M87507 Hs 2490 Hs 2490 caspaεe 1, apoptosis related cys 336
406698 X03068 Hs 73931 Hs 73931 major histocompalibility comple 336
439778 AL109729 Hs 99364 Hs 99364 abhydrotase domain containing 1 336
418862 BE550964 Hs 89399 NM.005176 Homo εapiens ATP synthase H+ 336
421140 AA298741 Hs 102135 NM.006280 Homo sapiens signal sequence r 336
451932 AA360954 Hs 27268 Hs 27268 Homo sapiens cDNA FU21933 fis 336
449042 AW294985 Hs 30715 Hs 30715 potassium voltage-gated channel 336
426746 J03626 Hs 2057 NM.000373 Homo sapiens undine monophosp 336
425725 NM.012243 Hs 159322 (tocuslιnk)NM_012243 Homo sapiens solute 335
444734 NM 001360 Hs 11806 NM.001360 Homo sapiens 7-dehydrocholeste 335
436415 BE265254 Hs 343258 NM.006191 Homo sapiens proliferation ass 335
457329 AI634860 Hs 359682 (tocuslιnk)NM_016442 Homo sapienε type 1 335
432169 Y00971 Hs 2910 NM.002765 Homo εapienε phosphoribosyl py 335
412525 AA581439 Hs 152328 Hs 152328 ESTs 335
416391 AI878927 Hs 79284 NM.002402 Homo sapiens mesoderm spxific 335
419193 D29643 Hs 34789 NM.005216 Homo sapiens dolichyl-diphσsph 335
432065 AA401039 Hs 2903 Hs 2903 protein phoεphatase 4 (formeriy 334
400262 Hs 75309 NM.001961 Homo εapiens eukaryotic transi 334
423598 BE247600 Hs 377968 NM.020400 Homo sapiens G protein-coupled 334
424291 AL120051 Hs 144700 NM.004429 Homo sapiens ephπn B1 (EFNB1) 334
450506 NM 004460 Hs 418 (tocuslmk)NM_004460 Homo sapiens fibrob 334
437296 AA350994 Hs 20281 Hs 20281 MAPK phosphatase 7 334
431731 BE266322 Hs 211374 (!∞uslιnk)NM_145051 Homo sapiens hypoth 334
425159 NM 004341 Hs 154868 NM.004341 Homo sapiens carbamoyl phospha 334
427349 AA360154 Hs 177415 (IxuslinkJNM 001997 Homo sapiens Finkel 334
439246 AI498072 Hs 351474 Hs 351474 Homo sapiens cDNA FU30002 fis 334
448775 AB025237 Hs 388 NM.002452 Homo sapiens nudix (nucleoside 334
407236 W79485 Hs 173980 Hs 173980 nuclear matnx protein NMP200 334
445350 AF052112 Hs 12540 NM.006330 Homo sapiens lysophoεpholipase 334
444706 AK000398 Hs 11747 (tocuslιπk)NM_017798 Homo sapiens chromo 334
429574 BE268321 Hs 208912 Hs 208912 hypothetical protein MGC861 333
427647 W19744 Hs 180059 Hs 180058 Homo sapiens cDNA FU31360 fis 333
415938 BE383507 Hs 78921 NM.003488 Homo sapiens A kinase (PRKA) a 333
414271 AK000275 Hs 75871 (lxuslιnk)NM_012408 Homo sapiens protei 333
424394 BE277024 Hs 146381 Hs 146381 RNA binding motif protein, X c 333
437186 AA338305 Hs 377816 Hs 377816 Homo sapiens cDNA FU36808 fis 332
430542 AI557486 Hs 119122 Hs 119122 πbosomal protein L13a 332
444019 BE173977 Hs 10098 NM.019082 Homo sapiens putative nucleola 332
434931 AW968941 Hs 166254 Hs 166254 likely ortholog of rat vxuole 332
426158 NM 001982 Hs 199067 NM.001982 Homo sapiens v-erb-b2 erythrob 332
430393 BE185030 Hs 241305 (tocuslιπk)NM_006470 Homo sapienε tπpar 332
402104 332
446620 AA128808 Hs 179902 (IxuslinkJNM 022109 Homo sapienε CDw92 332
443425 AI056776 Hs 133397 Hε 133397 ESTε 332
414883 AA926960 Hs 348669 Hs 348669 CDC28 protein kinase 1 331
413063 AL035737 Hs 75184 Hs 75184 chitinase 3-lιke 1 (cartilage g 331
451564 AU076698 Hs 132760 (l∞uεlιnk)NM_001467 Homo sapiens glucos 331
437822 AW450485 Hs 437 NM.000991 Homo sapiens πbosomal protein 331
441866 BE464341 Hs 21201 Hs 21201 necfan 3 331
438930 AW843633 Hε 343261 Hs 343261 histocompatibility (minor) 13 331
422192 AA305159 Hs 113019 NM.015931 Homo sapiens fls485 (LOC51066) 331
446506 AI123118 Hs 15159 (tocuslιnk)NM_016326 Homo sapiens chemok 331
415323 BE269352 Hs 949 NM.000433 Homo sapiens neutrophil cytoso 331
449644 AW960707 Hs 148324 Hs 148324 ESTs 331
422611 AA158177 Hs 118722 (lxuslιnk)NM_004480 Homo sapiens fucosy 331
417640 D30857 Hs 82353 NM.006404 Homo sapiens protein C rxepto 330
428157 AI738719 Hs 198427 NM 000189 Homo sapιenε hexokinase 2 (HK2 330
447321 AW271217 Hs 281434 Hs 281434 Homo sapiens cDNA FU31373 fis 330
450447 AF212223 Hs 25010 NM.018698 Homo sapiens hypothetical prot 330
422691 NM 003365 Hs 119251 NM.003365 Homo sapiens ubiqumol-cytochr 330
426375 AK000597 Hs 169549 NM.017893 Homo sapiens sema domain, immu 330
449230 BE613348 Hs 356392 Hs 356392 ESTs, Highly similar to S-phas 329
424756 AW504657 Hs 152931 (lxuslιnk)NM_002296 Homo sapiens lamm 329
442772 AW503680 Hs 5957 Hs 5957 Homo sapiens clone 24416 mRNA se 329
430281 AI878842 Hs 237924 NM 016016 Homo sapiens CGI 69 protein (L 329
448153 Y10805 Hs 20521 NM.001536 Homo sapiens HMT1 hnRNP methyl 329
420332 NM 001756 Hs 1305 NM.001756 Homo sapiens senne (or eystei 329
417691 AU076610 Hs 82399 NM.007357 Homo sapiens component of dig 329
412926 AI879076 Hs 75061 Hs 75061 mxrophage mynstoylated alaπiπ 328
427308 D26067 Hs 174905 Hε 174905 KIAA0033 protein 328
432026 AA524545 Hs 224630 Hs 224630 Homo sapiens cDNA FLJ33318 fis 328
449199 AI990122 Hs 196988 Hs 196988 ESTε 328
442739 NM 007274 Hs 8679 (l∞uslιnk)NM_007274 Homo sapiens cytoso 328
422051 AW327546 Hs 111024 (tocuslιnk)NM_005984 Homo sapiens solute 328
452714 AW770994 Hs 30340 Hs 30340 hypothetical protein KIAA1165 328
431884 AA521246 Hs 210792 Hs 210792 Homo sapiens cDNA FU36691 fis 328
402260 328
409686 AK000002 Hs 55879 (lxuslιπk)NM_033450 Homo sapiens multid 328
409267 NM 012453 Hs 52515 NM.012453 Homo sapiens transducin (beta) 328
447783 AF054178 Hε 19561 NM.005001 Homo sapiens NADH dehydrogenas 327
426812 AF105365 Hs 172613 NMJW6598 Homo sapiens solute earner fa 327 429671 BE379335 Hs 211594 Hs 211594 proteasome (prosome, mxropain 327 434521 NM.002267 Hs 3886 Hs 3886 karyopheπn alpha 3 (importm al 327 454128 AL031259 Hs 367900 Hs 367900 programmed cell death 2 327 _ 445033 AV652402 Hs 72901 NM.078487 Homo sapiens cyclm-dependent 327
5 448752 AA593867 Hs 300842 NM.024820 Homo sapiens KIAA1608 protein 326
425221 AV649864 Hs 155188 NM.005642 Homo sapiens TAF7 RNA polymera 326 440286 U29589 Hs 7138 NM.000740 Homo sapienε cholmergio rxep 326 413745 AW247252 Hs 75514 NM.000270 Homo sapiens nucleoside phoεph 326 412338 AA151527 Hs 69485 (tocuslmk)NM_024661 Homo sapiens hypoth 326 0 426520 BE545684 Hs 343566 Hs 343566 KIAA0251 protein 326
427640 AF058293 Hs 180015 NM.001355 Homo sapiens D-dopxhrome taut 326 440943 AW082298 Hs 146161 NM.032331 Homo sapiens hypothetical prot 326 425966 NM.001761 Hs 1973 NM.001761 Homo sapienε cyclin F (CCNF), 325 416448 L13210 Hs 79339 NM.005567 Homo sapiens Ixtm, galxtosi 325 5 449944 AF290512 Hs 58215 (lxuεlιnk)NM_033046 Homo εapiens rhotek 325
424381 AA285249 Hs 146329 NM.007194 Homo sapienε CHK2 chxkpoint h 325 426784 U03749 Hs 172216 NM.001275 Homo sapiens chromogranm A (p 325 420190 AI816209 Hs 95867 (tocuslιnk)NM_024112 Homo sapiens chromo 325 438085 R52518 Hs7967 Hs 7967 ESTs, Weakly similar to extensin 324 0 419216 AU076718 Hs 164021 NM.002993 Homo εapienε εmall inducible c 324
430154 AW583058 Hs 234726 NM.001085 Homo εapiens seπne (or cystei 324 458376 AB023179 Hs 9059 Hs 9059 KIAA0962 protein 324 410600 AW575742 Hs 351676 Hs 351676 Homo sapiens cDNA FU25921 fis 324 420676 AI434780 Hs 4248 Hs 4248 Homo sapiens PP3781 mRNA, comple 324 5 435640 AF220053 Hs 54960 NM.018468 Homo sapiens uncharxteπzed h 323
427775 R26944 Hs 180777 Hs 180777 Homo sapiens mRNA cDNA DKFZpδ 323 412600 L28824 Hs 74101 Hs 74101 spleen tyrosine kinase 323 430250 NM.016929 Hs 283021 NM.016929 Homo sapienε chloπde intrxel 323 432871 NM 016142 Hs 279617 Hs 279617 hydroxysteraid (17-beta) dehyd 323 0 432731 R31178 Hs 287820 Hs 287820 fibronectin 1 323 410340 AW182833 Hs 112188 (tocuslιnk)NM_021826 Homo sapienε hypoth 323 410047 AI167810 Hs 379753 Hs 379753 Homo sapiens cDNA FU33176 fis 323 430567 NM.003028 Hs 244542 Hs 244542 Homo sapiens cDNA FU38908 fis 323 425907 AA365752 Hs 155965 Hs 155965 ESTs 323 5 436075 BE090176 Hs 179902 NM.080546 Homo sapiens CDw92 antigen (CD 322
403912 322
429782 NM.005754 Hs 220689 Hs 220689 Ras GTPase-xtivatmg protein 322 416178 AI808527 Hs 192822 NM.030949 Homo εapiens protein phosphata 322 445229 BE276013 Hs 343828 Hs 343828 Homo sapiens mRNA, cDNA DKFZp7 322 0 422030 X51416 Hs 110849 (locuslιnk)NM_004451 Homo sapiens estrog 322
409591 AA532963 Hs 9100 Hs 9100 hypothetical gene supported by A 322 411531 AB014511 Hs 70604 Hs 70604 ATPase, Clasε II, type 9A 322 414820 AA371931 Hs 77422 Hs 77422 proteolipid protein 2 (colonic 322 450770 AA019924 Hs 28803 Hs 28803 ESTs 322 5 433233 AB040927 Hs 301804 Hs 301804 KIAA1494 protein 322
414172 AW954324 Hs 75790 (lxuslιnk)NM_002642.Homo εapiens phosph 321 428781 AF164799 Hs 193384 Hs 193384 putatative 28 kDa protein 321 432078 BE314877 Hs 24553 (lxuslιnk)NM_022369 Homo sapiens hypoth 321 454358 AW792876 Hs 288936 NM.031420 Homo sapienε it∞hondπal πb 321 0 447140 AF070537 Hs 17481 NM.138391 Homo sapiens hypothetical prot 321
409132 AJ224538 Hs 50732 NM.005399 Homo sapiens protein kinase, A 321 400836 320
420281 AI623693 Hs 323494 (lxuslιnk)NM_017964 Homo sapiens hypoth 320 _ _ 414343 AL036166 Hs 75914 NM.006815 Homo sapiens coated vesicle me 320 5 447096 BE539199 Hs 62112 (tocuslιnk)NM_003457 Homo εapiens zinc f 320
412276 BE262621 Hs 73798 Hs 73798 mxrophage migration inhibitory 320 425261 BE385099 Hs 355814 Hs 355814 Homo sapiens clone IMAGE 29333 320 407736 N41744 Hs 349326 Hs 349326 Homo sapiens cDNA FU30677 fis 320 400845 320 60 407082 Z47055 320
452012 AA307703 Hε 279766 (tocuslιnk)NM_012310 Homo εapienε kinesi 320 403217 320
414249 AI797994 Hs 279929 (lxuslιnk)NM_017510 Homo sapiens gp25L2 3 19 431243 U46455 Hs 252189 NM.002999 Homo sapiens syndxan 4 (amphi 3 19 65 417777 AI823763 Hs 7055 Hs 7055 Homo εapienε cDNA FU33420 fiε, 319
457274 AW674193 Hs 227152 NM.016391 Homo sapiens hypothetical prot 319 445139 AB037848 Hs 12365 Hs 12365 εyπaptotagmin XIII 3 19 430280 AA361258 Hs 237868 Hs 237868 Homo sapiens mRNA, cDNA DKFZp6 319 „ 422197 AW974265 Hs 111632 Hs 111632 Lsm3 protein 3 19
70 422938 NM 001809 Hs 1594 NM.001809 Homo sapiens centromere protei 3 18
435575 AF213457 Hs 44234 NM.018965 Homo sapienε tπggeπng recept 318 449704 AK000733 Hs 23900 Hs 23900 Rx GTPase xtivatmg protein 1 3 18 426925 NM 001196 Hs 172894 Hs 172894 BH3 interacting domain death a 3 18 _ _ 414814 D14697 Hs 77393 (tocuslιnk)NM_002004 Homo εapienε farneε 3 18
75 405387 318
444108 R55784 Hs 140942 Hε 140942 Homo sapiens cDNA FU38396 fis 3 18 424089 AL036662 Hε 144949 Hs 144949 ESTs 317 414788 X78342 Hs 77313 Hs 77313 cyclm-dependent kinase (CDC2 1 317 424927 AW973666 Hs 153850 Hs 153850 hypothetical protein C321 D24 317 80 451452 BE560065 Hε 26433 NM.001382 Homo sapienε dolichyl phosphat 317
426924 BE222542 Hs 128782 Hs 128782 Homo sapienε cDNA FU31512fiε 3 17 447032 AK000310 Hs 17138 (lxuslιnk)NM_017755 Homo sapiens hypoth 3 17 410663 AA194952 Hs 36093 Hs 36093 Homo sapiens cDNA FU12885 fis, 317 415402 AA164687 Hs 177576 Hs 177576 mannosyl (alpha-1,3-)-glycopro 3 17
451032 W03692 Hs 323079 Hs 323079 Homo sapiens mRNA cDNA DKFZpδ 3 17
412146 M92444 Hs 73722 Hs 73722 APEX nuclease (multifunctional 3 17
417018 M16038 Hs 80887 Hs 80887 v yes-1 Yamaguchi εarcoma viral 3 16
425244 AK002127 Hs 155313 NM.022105 Homo sapiens death asεxiated 3 16
417878 U90916 Hs 82845 Hε 82845 Homo εapiens cDNA FLJ21930 fis 3 16
426675 AW084791 Hs 133122 Hs 133122 hypothetical protein FU14524 3 16
432728 NM 006979 Hs 278721 NM.006979 Homo sapiens HLA class II regi 3 16
442643 U82756 Hs 374973 (locuslιnk)NM_004697 Homo sapiens PRP4 p 3 16
418462 BE001596 Hs 85266 Hs 85266 integnn, beta 4 3 16
429922 Z97630 Hs 226117 NM.005318 Homo εapiens H1 histone family 3 16
429556 AW139399 Hs 314807 Hs 314807 hypothetical protein MGC2655 3 15
418127 BE243982 Hs 83532 (l∞uslιnk)NM_002389 Homo sapienε membra 3 15
416293 BE244454 Hs 79162 Hε 79162 structure spxific recognition 3 15
435968 AW161481 Hs 111577 (locuslιπk)NM_030926 Homo sapienε integr 3 15
414702 L22005 Hs76932 NM.004359 Homo sapiens cell division eye 3 15
437672 AW748265 Hs 5741 NM 016230 Homo sapienε fiavohemoprotein 3 15
435750 AB029012 Hs4990 Hs 4990 KIAA1089 protein 3 14
432710 AA609685 Hs 278672 NM.005898 Homo sapiens membrane componen 314
407961 AW672939 Hs41694 Hs 41694 oπgin recognition complex, sub 3 14
438203 BE540090 Hε7345 Hs 7345 MAD1 mitotic arrest deficient Ii 3 14
426410 BE298446 Hs 305890 NM.138578 Homo sapienε BCL2-lιke 1 (BCL2 3 14
422282 AF019225 Hs 114309 (tocuslιnk)NM 003661 Homo sapiens apolip 314
450295 AI766732 Hs 210628 Hs 210628 ESTε 3 14
413900 AW409747 Hs 75612 NM.006819 Homo sapiens stress induced ph 3 13
452695 AW780199 Hs 30327 NM.003668 Homo sapienε mitogen activated 3 13
407797 AK000524 Hs 39850 Hs 39850 undine kmase-like 1 313
412006 AW451618 Hs 290216 Hs 290216 ESTs 3 13
424247 X14008 Hs 234734 NM.000239 Homo sapiens lysozyme (renal a 3 13
447627 AF090922 Hs 152738 NM.016050 Homo sapiens mitochondπal πb 3 13
422753 AI928995 Hs 1575 Hs 1575 small nuclear πbonucteopratein 3 12
441321 H17182 Hs 7771 NM.007273 Homo sapiens repressor of estr 3 12
411358 R47479 Hs 94761 Hs 94761 KIAA1691 protein 3 12
438444 AI064707 Hs 301226 Hs 301226 Homo sapiens, clone IMAGE 3456 3 12
424727 AW590378 Hs 378965 Hs 378965 Homo sapiens cDNA FU37658 fis 3 12
435975 AL118990 Hs 373554 (lxuslιnk)NM_130786 Homo sapiens alpha- 3 12
426680 AA320160 Hs 171811 NM.001625 Homo εapienε adenylate kinaεe 3 12
412326 R07566 Hs73817 NMJ02983 Homo sapiens small inducible c 3 12
409220 BE243323 Hs 51233 (IxuslinkJNM 003842 Homo sapiens tumor 3 12
428699 AW578252 Hs 190161 Hε 190161 LR8 protein 3 12
422675 BE018517 Hs 119140 NM.001970 Homo sapiens eukaryotic transi 3 12
444301 AK000136 Hs 10760 NM.017680 Homo sapiens aspoπn (LRRclas 3 12
409932 AI376750 Hs 57600 NM.001283 Homo sapiens adaptor-related p 3 12
419152 L12711 Hs 89643 (lxuslιnk)NM_001064 Homo sapiens transk 3 12
410240 AL157424 Hs 61289 Hs 61289 syπaptojaπιn 2 3 12
413073 AL038165 Hs75187 NM.014765 Homo sapienε translxase of ou 311
406865 AI025931 Hs 181357 Hs 181357 laminin receptor 1 (67kD, πbo 3 11
405203 3 11
441028 AI333660 Hs 17558 Hs 17558 Homo sapienε, clone IMAGE 40704 3 11
417211 T97617 Hs 269092 Hs 269092 ESTs 311
421684 BE281591 Hs 106768 NM.018120 Homo sapiens hypothetical prot 3 11
429824 AA296363 Hs 121520 Hs 121520 Homo sapienε cDNA FU35792fiε 3 11
426234 BE314534 Hs 168159 Hs 168159 bifunctional apoptosis regulat 3 11
408805 H69912 Hs48269 NM.003384 Homo sapiens vaccinia related 3 10
417821 BE245149 Hs 82643 NM.002822 Homo sapiens protein tyrosine 3 10
416976 BE243985 Hs 80680 Hs 80680 major vault pratem 310
410013 AF067173 Hs 57904 Hs 57904 mago-nashi homolog, proliferati 3 10
429597 NM.00381Ei Hs2442 Hs 2442 a disintegnn and metallopratein 3 10
453518 AW503205 Hε 27268 Hs 27268 Homo εapiens cDNA FU21933 fiε 3 10
429238 NM 00284Ϊ ) Hs 198288 NM.002849 Homo εapiens pratem tyrosine 3 10
433409 AI278802 Hs 25661 Hs 25661 ESTs, Moderately similar to hyp 3 10
426440 BE382756 Hs 169902 NM.006516 Homo sapiens solute earner fa 3 10
435472 AW972330 Hs 283022 NM.018643 Homo sapiens tπggenng recept 3 10
427609 AK000436 Hs 179791 NMJ17817 Homo sapiens RAB20, member RAS 3 10
408201 AK000568 Hs 43654 NM.017882 Homo sapiens ceroid lipofuscm 3 10
'418181 U37012 Hs 83727 NM.013291 Homo sapienε cleavage and poly 3 10
445176 AI878907 Hs 12379 NMJ01419 Homo sapiens ELAV (embryonic I 3 10
436906 H95990 Hε 181244 Hs 181244 major histocompatibility compl 3 10
427337 Z46223 Hε 176663 NM.000569 Homosapiens Fc fragment of Ig 3 10
433435 BE545277__Hs 340959 NM.005726 Homo sapiens Ts translation el 309
408150 BE620274 Hs43112 Hε 43112 Homo sapiens mRNA, cDNA DKFZp43 309
431738 AW237726 Hs 288549 NM.032828 Homo sapiens ubiquitin UBF-fl 309
449703 H61001 Hs 171802 Hs 171802 Homo sapienε, clone IMAGE 3956 309
423184 NM.004428 Hs1624 NM.004428 Homo sapiens ephπn-A1 (EFNA1) 309
400278 Hs 2280 NM.002950 Homo sapienε πbophoπn I (RPN 309
449051 AW961400 Hs 333526 NM.032339 Homo sapiens hypothetical prot 309
428297 AA236291 Hs 183583 NM.030666 Homo sapiens seπne (or cystei 309
430066 AI929659 Hs 237825 Hs 237825 signal recognition particle 72 309
428044 AA093322 Hs 301404 NM.006743 Homo εapienε RNA binding motif 309
426989 AI815206 Hs 100293 Hε 1002930 linked N xetylglucoεamine ( 308
447887 AA114050 Hs 211610 NM.001228 Homo sapiens caspase 8, apopto 308
422010 AA302049 Hs 31181 Hs 31181 Homo sapiens cDNA FU23230 fis 308
444823 BE262989 Hs 12045 Hs 12045 C2f protein 308 410668 BE379794 Hε 159651 NM.014452 Homo sapiens tumor nxrosis fa 308
415173 AW501735 Hs 180059 Hs 180059 Homo sapiens cDNA FU31360 fis 308
419757 AA773820 Hs 63970 Hs 63970 ESTε 308
427725 U66839 Hs 180533 NM.002756 Homo εapienε mitogen activated 308
424408 AI754813 Hs 146428 Hs 146428 collagen, type V, alpha 1 308
453914 NM 000507 Hs 574 NM.000507 Homo sapiens fructose-1,6 bisp 308
420187 AK001714 Hs 95744 NM.019028 Homo εapiens hypothetical prot 308
431498 AK001777 Hs 258551 NM.012100 Homo sapiens aspartyl aminopep 307
411423 AW845987 Hs 68864 (locuslιπk)NM_139248 Homo εapienε membra 307
449954 AA641636 Hs 37477 Hε 37477 ESTs, Weakly similar to T46220 307
423671 AW860155 Hs 234101 Hs 234101 Homo sapιens, sιmιlarto cholι 307
448719 AA033627 Hs 21858 Hε 21858 seπne (or cysteine) proteinase 307
451455 AI937227 Hs 8821 NM.021175 Homo sapiens hepcidin antimicr 307
450876 AF189062 Hs 285976 (l∞uslmk)NM_013384 Homo sapiens LAG1 1 307
432465 D56165 Hs 275163 NM.O02512 Homo sapienε non metastatic ce 307
421808 AK000157 Hs 108502 NM.017688 Homo sapiens hypothetical prot 307
430014 H59354 Hs 374303 (l∞uslιnk)NM_144691 Homo sapiens hypoth 307
436553 AW407157 Hs 181125 Hs 181125 immunoglobulin lambda tocuε 306
458814 AI498957 Hs 351937 Hs 351937 nbosomal protein, large P2 306
450247 AF123303 Hs 24713 NM.013386 Homo sapiens hypothetical prot 306
418062 AW630656 Hs 83383 NM.006406 Homo εapiens peroxiredoxm 4 ( 306
407223 H96850 H96850 yw03b12 s1 Soares elaπocyte 2NbH 306
418641 BE243136 Hs 86947 NM.001109 Homo sapiens a disintegnn and 306
450690 AA296696 Hs 333418 (tocuslιπk)NM_014164 Homo sapiens FXYD d 306
408124 U89337 Hε 42853 NM.004381 Homo εapiens cAMP responsive e 306
435550 AI224456 Hs 324507 Hs 324507 hypothetical protein FU20986 306
421779 AI879159 Hs 108219 NM.004626 Homo sapiens wingless type MMT 305
440246 W52010 Hs 191379 Hs 191379 ESTε 305
446770 AV660309 Hs 154986 Hs 154986 ESTs, Weakly similar to PLLP.H 305
440708 AF038962 Hs 7381 Hs 7381 voltage-dependent aπion channel 305
425118 AU076611 Hs 154672 Hε 154672 methylene tetrahydrofolate deh 305
453830 AA534296 Hs 20953 Hs 20953 hypothetical protein BC010003 305
412867 AU076861 Hs 74637 Hs 74637 tests enhanced gene transcπpt 305
422032 AA476966 Hs 110857 NM.016310 Homo εapienε polymerase (RNA) 305
441238 AI372555 Hs 322456 NM.032039 Homo sapienε hypothetical prot 305
408524 D87942 Hs 46328 Hs 46328 fucosyltransferase 2 (sxretor 305
408102 U46351 Hs 621 Hs 621 Ixtin, galactoside-bindmg, solu 305
430508 AI015435 Hs 104637 Hs 104637 solute earner family 1 (gluta 304
432281 AK001239 Hs 274263 Hs 274263 hypothetical protein FU10377 304
443883 AA114212 Hε 9930 Hs 9930 εenne (or cysteine) proteinase 304
423570 AW838306 Hε 129819 NM.018344 Homo sapiens hypothetical prot 304
443653 AA137043 Hs 9663 NM.013374 Homo sapiens programmed cell d 304
451711 AK000461 Hs 26890 NM.017829 Homo sapiens cat eye syndrome 304
444736 AA533491 Hs 23317 NM.032824 Homo sapiens hypothetical prot 304
407687 AK002011 Hs 37558 NM~018339 Homo sapiens hypothetical prot 304
423022 AA320525 Hs 201076 Hs 201076 ESTs 304
453450 AW797627 Hs 347459 Hs 347459 Homo sapiens cDNA FLJ13900 fis 304
412708 R26830 Hs 106137 Hs 106137 Homo sapiens mRNA for OK/SW CL 304
448569 BE382657 Hs 21486 Hs 21486 εignal transducer and xtivator 304
443329 BE262943 Hs 9234 NM.032635 Homo sapiens seven transmembra 303
439018 AW300887 Hs 26638 NM.031457 Homo sapiens membrane-spanning 303
412627 BE391959 Hs 74276 Hs 74276 chloπde intracellular channel 303
444309 U83236 Hs 10803 Hs 10803 calcium and integπn binding 1 303
412969 AI373162 Hs 75103 NM.003406 Homo sapiens tyrosine 3-monoox 303
430354 AA954810 Hs 239784 Hs 239784 scπbble 303
414774 X02419 Hs 77274 NM.002658 Homo sapiens plasminogen xtiv 303
450607 AL050373 Hs 25213 NM.015677 Homo εapiens hypothetical prot 303
421179 U72664 Hε 148495 NM 002810 Homo sapiens proteasome (proso 302
451798 BE297567 Hs 27047 Hs 27047 hypothetical protein FU20392 302
428428 AL037544 Hs 184298 NM.001799 Homo sapiens cyclm-dependent 302
447656 NM.003726 Hs 19126 NM.003726 Homo εapienε src family assxi 302
436823 AW749865 Hs 117077 Hs 117077 zinc finger protein 264 302
417896 AA379770 Hs 82890 Hs 82890 defender against cell death 1 302
444193 Y17801 Hs 10574 Hs 10574 solute camerfamily 2, (fxil 302
418741 H83265 Hs 8881 Hs 8881 Homo sapienε cDNA FU32163 fiε, 301
414421 AI521130 Hs 355126 (locuslmk)NM_144686 Homo sapiens hypoth 301
424867 A1024860 Hs 153591 NM.005787 Homo sapiens Not56 (D melanog 301
442504 BE503373 Hs 334335 NM.022484 Homo sapiens hypothetical prot 301
437651 BE560672 Hs 13543 (tocuslιnk)NM_145214 Homo sapiens tnpar 301
436540 BE397032 Hs 14468 NM.020230 Homo sapiens peter pan homolog 300
438000 AI825880 Hs 5985 Hs 5985 non kinase Cdc42 effector protei 300
415697 AI365603 Hs 279696 Hs 279696 DKFZP566I1024 protein 300
437469 AW753112 Hs 15514 Hs 15514 hypothetical protein MGC3260 300
436319 H90727 Hs 5123 Hs 5123 hypothetical protein BC008246 300
450126 BE018138 Hs 24447 (tocuslιnk)NM_005866 Homo sapienε type I 300
445985 BE621800 Hs 29444 Hs 29444 putative small membrane protein 300
406868 AA505445 Hs 300697 Hs 300697 immunoglobulin heavy constant 300
424439 AA579635 Hs 1770 Hε 1770 ligase I, DNA, ATP-dependent 300
408452 AA054683 Hs 222728 Hs 222728 Homo sapiens cDNA FU39004 fis 300
417831 H16423 Hs 82685 Hs 82685 CD47 antigen (Rh related antige 300
TABLE 11B Pkey: Unique Eos probeset identifier number
CAT number: Gene cluster number Accession: Genbank xcession numbers
Pkey CAT Number Accession
406685 0 0 M18728 432407 MH1429.12 BG036675 BF772005 BF771866 BG960386 BG960381 NM.005712 AF110315 BE074534 BE182776 BE158000 BE157999 BE714315 AW818104
AW847519 AA099426 AW817981 AW856396 BG961122 AA224498 AA308542 AW821833 BF902155 AI732411 BG778834 BG283641 BE748279
BE748870 BG319540 BE748864 BF739224 BG986155 AK057283 BI861466 AA663341 AA457591 BG949294 AW392886 AA071122 AA227849
AA584918 BG959570 BF773486 AL041698 BF959013 R87170 C16859 BF770411 BF771298 AI075321 L13823 AA216700 BF771864 AW861859
BE537068 C18935 AA155719 BF771172 BF769107 BF804964 AW818172 AW818143 AW392930 AW817057 AW858044 BF746211 AA179928
AW861687 AW821826 BI055726 BF242643AA207189 BF770412 BF771157 BG430030AA055592
459306 223120.4 AW578452 452098 161393.1 BG028348 BF772844 H83066 AW817969 H90985 BF755039 AI858183 451129 1495511.1 BE072881 AI762181 BE072946
TABLE 11C
Pkey: Unique number corresponding to an Eos probeset
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489495. Strand: Indicates DNA strand from which exons were predicted.
NLposition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLposition
406399 9256288 Minus 63448-63554
403220 7630969 Plus 64338-64517
403218 7630969 Plus 58039-58149
403221 7630969 Plus 66294-66438,66936-67124
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
400529 9796988 Plus 138232-138423
405556 1552511 Plus 163497-163623,164715-164968,165369-16550
403739 7630882 Plus 4456344766,48209-48483,52255-52495
403219 7630969 Plus 61858-61995
404826 6572184 Plus 4772648046
400750 8119067 Plus 198991-199168,199316-199548
400846 9188605 Plus 39310-39474
401179 9438647 Plus 113477-113893
400847 9188605 Plus 4464344835
404854 7143420 Plus 14260-14537
400448 9887687 Minus 177372-177674
404240 5002624 Minus 116132-116407,116653-116922
402829 8918414 Plus 101532-101852,102006-102263
406363 9256114 Plus 14403-14602,17000-17147,17241-17368
402104 8119072 Plus 122409-122600
402260 3399665 Minus 113765-113910,115653-115765,116808-11694
403912 7710730 Minus 72000-72290,72431-72700,72929-73199
400836 8954179 Plus 677-1188
400845 9188605 Plus 34428-34612
403217 7630969 Plus 54089-54163,55427-55623
405387 6587915 Minus 3769-3833,5708-5895
405203 7230116 Plus 125295-125463
Table 12A lists about 1006 genes up-regulated in cervical cancer compared to normal adult tissues. These were selxted from 59680 probesets on the Affymetrix/Eos-Hu03 GeneChip array such that the ratio of "average" cervical cancer to "average" normal adult tissues was greater than or equal to 2.5. The "average" cervical cancer level was set to the 93rd percentile value amongst cervical cancerε. The "average" normal adult tissue level was set to the 93"1 percentile value amongst non-malignant tissues. In order to remove gene- spxific bxkground levels of non-spxific hybridization, the 15* percenfile value amongst non-malignant tisεues was subtrxted from both the numerator and the denominator before the ratio was evaluated.
TABLE 12A: 1006 GENES UP-REGULATED IN CERVICAL CANCER COMPARED TO NORMAL ADULT TISSUES
Pkey: Unique Eos probeset identifier number
ExAccn: Exemplar Accession number, Genbank xcession number
UnigenelD: Unigene number
Unigene Title: Unigene gene title
R1: Ratio of tumor to normal body tissue
Pkey ExAccn UnigenelD Unigene Title R1
402075 U19557 Hs.123035 squamous cell carcinoma antigen 2 (SCCA2) 81.1
425650 NM 001944 Hs.1925 desmoglein 3 (pemphigus vulgaris antigen) 43.6
418007 M13509 Hs.83169 matrix metaltoproteinase 1 (interstitial coll 38.9
435094 AI560129 Hs.329062 EST 30.3
439606 W79123 Hs.58561 G protein-coupled rxeptor 87 28.8
452240 AI591147 Hε.61232 ESTs 27.0
444783 AK001468 Hs.62180 anillin (Drasophila Scraps homolog), xtiπ bi 26.0
417034 NM.006183 Hs.80962 πeurotensin 25.5
424046 AF027866 Hs.138202 serine (or cysteine) proteinase inhibitor, cl 24.5
422956 BE545072 Hs.122579 hypothetical protein FLJ 10461 23.7 435505 AF200492 Hs.211238 interleukin-1 homolog 1 21.2
400289 X07820 Hs.2258 matrix metaltoproteinase 10 (stro elyεin 2) 20.5
418345 AJ001696 Hs.241407 εerine proteinaεe inhibitor 13 (PI13; εerpin 20.1
452461 N78223 Hs.108106 transcription factor 19.8
423017 AW178761 Hs.227948 serine (or cysteine) proteinaεe inhibitor, cl 19.2
429432 AI678059 Hs.202676 synaptoπemal complex protein 2 17.5
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-type, 16.4
435243 AW292886 Hs.261373 hypothetical protein dJ434014.3 16.3
428664 AK001666 Hs.189095 similar to S ALL1 (sal (Droεophila)-like 16.2
428227 AA321649 Hs.2248 small inducible cytokine subfamily B (Cys-X-C 15.9
421373 AA808229 Hs.167771 ESTε 15.7
416209 AA236776 Hs.79078 MAD2 (mitotic arrest deficient, yeast, homolo 15.4
441459 AI919142 Hε.214233 ESTs, Weakly similar to ALULHUMAN ALU SUBFAM 14.6
447164 AF026941 Hs.17518 Homo sapiens cig5 mRNA, partial sequence 13.8
412719 AW016610 Hs.129911 ESTs 13.4
417366 BE185289 Hs.1076 small praline-rich protein 1B (cornifin) 13.3
431753 X76029 Hs.2841 neuromedin U 13.2
438817 AI023799 Hs.163242 ESTs 13.1
404996 Target Exon 13.1
443211 AI128388 Hs.143655 ESTs 12.9
414764 AW013887 Hs.72047 ESTs- 12.9
« 428618 AA885360 Hs.160199 Target CAT 12.7
416661 AA634543 Hs.79440 IGF-II mRNA-binding protein 3 12.7
421478 AI683243 Hs.97258 ESTs, Moderately similar to S29539 ribosomal 12.6
429486 AF155827 Hs.203963 hypothetical protein FU 10339 12.6
432666 AW204069 Hs.312716 ESTs, Weakly similar to unnamed protein produ 12.6
427585 D31152 Hs.179729 collagen, type X, alpha 1 (Schmid metaphyseal 12.6
419183 U60669 Hs.89663 cytochrome P450, εubfamily XXIV (vitamin D 24 12.3
450221 AA328102 Hs.24641 cytoskeletoπ associated protein 2 12.2
422168 AA586894 Hs.112408 S100 calcium-binding protein A7 (psoriasin 1) 11.6
415989 AI267700 Hs.317584 ESTs 11.5
452838 U65011 Hs.30743 preferentially expressed antigen in melanoma 11.4
447048 AW393080 Hs.228320 hypothetical protein FU23537 11.3
453922 AF053306 Hs.36708 budding uninhibited by benzimidazoles 1 (yeas 11.0
449260 AA741180 Hs.29879 ESTs 11.0
423049 X59373 Hs.188023 ESTs, Moderately similar to HXDA.HUMAN HOMEOB 10.7
406467 Target Exon 10.5
439926 AW014875 Hs.137007 ESTε 10.2
428368 BE440042 Hs.83326 matrix metaltoproteinase 3 (stromelyεin 1, pr 10.2
420759 T11832 Hs.127797 Homo sapiens cDNA FU11381 fis, clone HEMBA10 10.2
414422 AA147224 Hs.337232 Homx box A13 10.2
442660 AW138174 Hs.130651 ESTs 10.1
449003 , X76342 Hs.389 alcohol dehydrogenase 7 (class IV), mu or sig 10.0
408572 AA055611 Hs.226568 ESTs, Moderately similar to ALU4.HUMAN ALU SU 9.9
439820 AL360204 Hs.283853 Homo sapienε mRNA full length insert cDNA clo 9.8
400195 NM 007057 NM 007057*:Homo sapienε ZW10 interxtor (ZWIN 9.8
422426 W79117 Hs.58559 ESTs 9.7
447700 AI420183 Hs.171077 ESTs, Weakly similar to T21259 hypothetical p 9.7
458194 AW383618 Hε.265459 ESTs, Moderately similar to ALU2.HUMAN ALU SU 9.4
455601 AI368680 Hs.816 SRY (sex determining region Y)-box 2 9.4
418882 NM 004996 i Hs.89433 ATP-binding cassette, sub-family C (CFTR/MRP) 9.4
437789 AI581344 Hs.127812 ESTs, Weakly similar to T17330 hypothetical p 9.4
419247 S65791 Hs.89764 fragile X mental retardation 1 9.1
419750 AL079741 Hs.183114 Homo sapiens cDNA FU14236 fis, clone NT2RP40 9.1
420602 AF060877 Hs.89236 regulator of G-protein signalling 20 9.0
428845 AL157579 Hs.153610 KIAA0751 gene product 9.0
426427 M86699 Hs.169840 TTK protein kinase 9.0
--429538 BE182592 Hs.11261 small proline-rich protein 2A 9.0
* 446232 AI281848 Hs.194691 retinoic xid induced 3 8.9
430520 NM 01619C ) Hs.242057 chromosome 1 open reading frame 10 8.9
439772 AL365406 Hs.10268 Homo sapiens mRNA full length insert cDNA clo 8.9
424905 NM 002497 Hs.153704 NIMA (never in mitosis gene a)-related kinase 8.9
423020 AA383092 Hs.1608 replication protein A3 (14kD) 8.9
430486 BE062109 Hε.241551 chloride channel, calcium xtivated, family m 8.7
452291 AF015592 Hs.28853 CDC7 (cell division cycle 7, S. cerevisiae, h 8.7
432193 AA372264 Hs.273193 hypothetical protein FU 10706 8.7
407642 AW178963 gb:MRO-ST0032-200899-001-b11 ST0032 Homo sapi 8.7
422420 U03398 Hs.1524 tumor nxrosis fxtor (ligand) superfamily, m 8.7
458027 L49054 Hs.85195 myeloid leukemia fxtor 1 8.4
424086 AI351010 Hs.102267 lysyl oxidase 8.3
420092 AA814043 Hs.88045 ESTs 8.3
449034 AI624049 gb:ts41 a09.x1 NCI.CGAP.Ut1 Homo sapiens cDNA 8.3
408522 AI541214 Hs.46320 Small proline-rich protein SPRK [human, odont 8.2
418478 U38945 Hs.1174 cycliπ-dependent kinase inhibitor 2A (melanom 8.2
436279 AW900372 Hs.180793 ESTε, Weakly similar to S65657 alpha-1 C-adren 8.2
440834 AA907027 Hs.128606 ESTs 8.2
452724 R84810 Hs.30464 cyclin E2 8.1
423849 AL157425 Hs.133315 Homo sapiens mRNA; cDNA DKFZp761J1324 (from c 8.1
410044 BE566742 Hs.58169 highly expressed in cancer, rich in leucine h 8.0
429228 AI553633 Hs.337139 ESTs 7.9
438915 AA280174 Hs.285681 Williams-Beureπ syndrome chromosome region 14 7.9
425710 AF030880 Hs.159275 solute earner family, member 4 7.8
421308 AA687322 Hs.192843 leucine zipper protein FKSG14 7.8 435159 AA668879 Hs 116649 ESTs 77
439232 N48590 Hs 46693 ESTs 77
437616 AI797163 Hs 207954 ESTs 76
406554 Target Exon 74
433133 AB027249 Hs 104741 PDZ-bindmg kinase T-cell onginated protein 74
424098 AF077374 Hs 139322 small proline nch protein 3 73
418134 AA397769 Hs 86617 ESTs 7 2
446364 AB006624 Hs 14912 KIAA0286 protein 72
447254 NM 004153 Hs 17908 oπgin recognition complex subunit 1 (yeast 7 1
414148 BE084049 gb PM0-BT0651-270400-003-IO2 BT0651 Homo sapi 70
429548 AW138872 Hs 135288 ESTs 70
423725 AJ403108 Hs 132127 hypothetical protein L0C57822 70
450192 AA263143 Hs 24596 RAD51 interacting protein 70
450149 AW969781 Hs 132863 Zic family member 2 (odd paired Drasophila ho 69
431941 AK000106 Hs 272227 Homo sapienε cDNA FU20099 fiε, clone COL0454 69
427821 AA470158 Hs 98202 ESTs 69
436211 AK001581 Hs 334828 hypothetical protein FU10719, KIAA1794 prate 69
425761 AW664214 Hs 196729 ESTs 69
450028 AI912012 Hs 200737 ESTs 68
409719 AI769160 Hs 108681 Homo sapiens brain tumor assxiated protein N 68
444342 NM 014398 Hs 10887 similar to lysosome assxiated membrane glyco 68
413573 AI733859 Hs 149089 ESTs 68
422330 D30783 Hs 115263 epiregulin 68
454988 AW850140 gb IL3-CT0219-261099-023-D11 CT0219 Homo sapι 68
447342 AI199268 Hs 19322 Homo εapiens, Similarto RIKEN cDNA 2010317E2 68
403471 Target Exon 67
409041 AB033025 Hs 50081 KIAA1199 protein 67
407839 AA045144 Hs 161566 ESTs 66
415652 T79213 Hs 272073 ESTs 66
420900 AL045633 Hs 44269 ESTs 66
444271 AW452569 Hs 149804 ESTs 66
410153 BE311926 Hs 15830 hypothetical protein FU12691 65
448693 AW004854 Hs 228320 hypothetical protein FU23537 65
431622 AW979271 Hs 293184 ESTs 65
457405 AA504860 gb ab03a10 s1 Stratagene fetal retina 937202 64
424345 AK001380 Hs 145479 Homo εapiens cDNA FU10518 fis, clone NT2RP20 64
414812 X72755 Hs 77367 monokine induced by gamma interferon 64
425734 AF056209 Hs 159396 peptidylglycme alpha-amidating monooxygenase 63
446435 AW206737 Hs 253582 ESTs 63
421948 L42583 Hs 334309 keratin 6A 63
419335 AW960146 Hs 284137 hypothetical protein FU 12888 63
429259 AA420450 Hs 292911 ESTs, Highly similar to S60712 band 6-proteιπ 62
406747 AI925153 Hs 217493 annexin A2 62
453884 AA355925 Hs 36232 KIAA0186 gene product 62
423735 AA330259 gb EST33963 Embryo, 12weekll Homo sapιens c 62
421773 W69233 Hs 112457 ESTs 62
457435 AW972024 Hs 142653 ret finger protein 6 1
450025 AK001875 Hs 24321 Homo sapiens cDNA FU12028 fis, clone HEMBB10 6 1
427043 AA397679 Hs 3991 ESTs 6 1
409723 AW885757 Hs 257862 ESTs 61
459462 AA481396 Hs 105167 ESTs 6 1
423244 AL039379 Hs 209602 ESTs, Weakly similar to ubiquitous TPR motif, 60
427217 AA399272 Hs 144341 ESTs 60
441820 AA969119 Hs 143502 ESTs, Weakly similar to envelope protein [H ε 60
437958 BE139550 Hs 121668 ESTε, Moderately similar to PC4259 femtin a 60
430791 AA486293 Hs 272068 ESTs, Weakly similar to ALU3.HUMAN ALU SUBFAM 59
416734 H81213 Hs 14825 ESTs, Weakly similar to KIAA1503 protein [H s 59
413385 M34455 Hs 840 indoleamme-pyrrole 2,3 dioxygenase 59
434828 D90070 Hε 96 phorbol 12 mynstate-13-xetate-ιπduced prate 59
414299 AA142989 Hε 71730 ESTε 58
439292 AA090421 Hs 5555 hypothetical protein MGC5347 58
413753 U17760 Hs 75517 laminin, beta 3 (nicem (125kD), kalinm (140 58
413625 AW451103 Hs 71371 ESTs 58
416049 AI970536 Hs 16603 hypothetical protein FU13163 58
415064 AA159804 Hs 149305 hypothetical protein MGC2603 57
425695 NM 005401 I Hs 159238 protein tyrosine phosphatase, non rxeptor ty 57
451381 BE241831 Hε 172330 hypothetical protein MGC2705 57
415900 Z43758 Hs 26037 ESTs 57
444478 W07318 Hs 240 M phase phosphoprotein 1 57
449611 AI970394 Hs 197075 ESTs 57
420637 AW976153 gb EST388262 MAGE resequences, MAGN Homo sapi 57
438639 AI278360 Hs 31409 ESTs 57
414972 BE263782 Hs 77695 KIAA0008 gene product 57
438394 BE379623 Hs 27693 peptidylpralyl isomerase (cyclophilm) like 1 56
428365 AA295331 Hs 183861 Homo sapiens cDNA FU20042 fis clone COL0042 56
407746 AK001962 Hs 38114 hypothetical protein FU11100 56
452401 NM 007115 Hs 29352 tumor nxrosis fxtor, alpha-induced protein 55
432239 X81334 Hs 2936 matnx metalloprotemase 13 (collagenase 3) 55
451307 AW293207 Hε 211516 ESTs 55
441531 AW291239 Hε 271111 ESTs 55
418663 AK001100 Hs 41690 desmxollin 3 55
410659 AI080175 Hs 68826 ESTs 55
432869 AW974094 gb EST386197 MAGE resequenceε, MAGM Homo sapi 55 431255 AA497043 Hs.115685 ESTs 5.5
407366 AF026942 gb:Homo sapiens cig33 mRNA, partial sequence. 5.5
433091 Y12642 Hs.3185 lymph∞yte antigen 6 complex, Ixus D 5.4
418502 R99288 Hs.35152 ESTs 5.4
440320 AA879294 gb:nw86e09.s1 NCI.CGAP.Pr12 Homo εapiens cDNA 5.4
439579 AF086400 gb:Homo sapiens full length insert cDNA clone 5.4
420783 AI659838 Hs.99923 Ixtiπ, galxtoside-biπding, soluble, 7 (gale 5.4
408536 AW381532 Hs.135188 ESTs 5.4
408758 NM.003686 Hε.47504 . exonuclease 1 5.4
451411 AA017492 Hs.135655 EST 5.4
424834 AK001432 Hs.153408 Homo sapiens cDNA FLJ10570 fis, clone NT2RP20 5.3
407853 AA336797 Hs.40499 diekkopf (Xenopus laevis) homolog 1 5.3
412140 AA219691 Hs.73625 RAB6 interxting, kinesiπ-like (rabkiπesiπ 6) 5.2
420026 AI831190 Hs.166676 ESTs 5.2
427356 AW023482 Hs.97849 ESTs 5.2
420440 NM.002407 Hs.97644 mammaglobin 2 5.2
430082 AW514083 Hs.190135 ESTs 5.2
445259 AI798994 Hs.152923 ESTs 5.2
457345 AI699933 Hs.192175 ESTε 5.2
453161 AA628608 Hs.61656 ESTs 5.2
445019 AI205540 Hε.281295 ESTs 5.2
425420 BE536911 Hs.234545 hypothetical protein NUF2R 5.2
439706 AW872527 Hs.59761 ESTs, Weakly similarto DAP1.HUMAN DEATH-ASSO 5.2
431494 AA991355 Hε.298312 hypothetical protein DKFZp434A1315 5.2
443179 AI928402 Hε.6933 hypothetical protein FU 12684 5.2
432226 AW182766 Hs.273558 phosphate cytidylyltransferase 1, choline, al 5.2
441020 W79283 Hs.35962 ESTs 5.1
437044 AL035864 Hs.69517 cDNA for differentially expressed C016 gene 5.1
419520 AB009303 Hs.90800 matrix metaltoproteinase 16 (membrane-inserte 5.1
430563 AA481269 Hs.108660 ATP-binding cassette, sub-family C (CFTR/MRP) 5.1
405547 NM 018833*:Homo sapienε transporter 2, ATP-bi 5.1
435206 AI432364 Hs.160594 ESTs 5.1
409269 AA576953 Hs.22972 hypothetical protein FU 13352 5.1
439223 AW238299 Hs.250618 UL16 binding protein 2 5.1
413251 AI932903 Hs.211535 ESTs 5.1
426320 W47595 Hs.169300 transforming growth factor, beta 2 5.1
458829 AI557388 gb:PT2.1 6 G03.r tumor2 Homo sapiens cDNA 3', 5.0
416208 AW291168 Hε.41295 ESTs, Weakly similar to MUC2 HUMAN MUCIN 2 PR 5.0
432473 AI202703 Hs.152414 ESTs 5.0
418738 AW388633 Hs.6682 solute carrier family 7, (cationic amino xid 5.0
423634 AW959908 Hs.1690 heparin-binding growth fxtor binding protein 5.0
426350 NM 003245 Hs.2022 transglutamiπase 3 (E polypeptide, protein-gl 5.0
432867 AW016936 Hs.233364 ESTs 5.0
449448 D60730 Hs.57471 ESTs 5.0
409744 AW675258 Hs.56265 Homo sapiens mRNA; cDNA OKFZp586P2321 (tram c 4.9
405657 C7000246:gi|72477|pir||DVHY1C multidrug resiε 4.9
429682 NM.006306 Hs.211602 SMC1 (structural maintenance of chromosomes 1 4.9
446704 AI337228 Hs.197083 ESTs 4.9
434376 AA631492 Hs.23921 hypothetical protein DKFZp547A023 4.9
407378 AA299264 Hs.57776 ESTs, Moderately similar to I38022 hypothetic 4.9
421155 H87879 Hs.102267 lysyl oxidase 4.9
443335 T89697 Hs.16645 ESTs 4.9
444461 R53734 Hε.25978 ESTs, Weakly similar to 2109260A B cell growt 4.8
410361 BE391804 Hs.62661 guanylate binding protein 1, interferon-induc 4.8
423673 BE003054 Hs.1695 matrix metalloproteinase 12 (mxrophage elaεt 4.8
441720 AI346487 Hs.28739 ESTs 4.8
442980 AA857025 Hs.8878 kinesin-like 1 4.8
450375 AA009647 Hε.8850 a disintegrin and metalloproteinase domain 12 4.8
417592 AA204664 Hs.182437 ESTs, Weakly similar to I54383 chromosome seg 4.8
429846 AB023021 Hs.225945 fucosyltransferase 9 (alpha (1 ,3) fucosyltran 4.8
418939 AW630803 Hs.89497 lamin B1 4.7
417235 AA810278 Hε.24250 ESTs 4.7
411958 AA099020 gb:zn45h01.s1 Stratagene HeLa cell s3937216 4.7
433858 N69243 Hs.192974 hypothetical protein FU12735 4.7
450434 AA166950 Hs.195870 hypothetical protein FU14991 4.7
418379 AA218940 Hs.137516 fidgetin-like 1 4.7
401747 Homo sapiens keratin 17 (KRT17) 4.7
439759 AL359055 Hs.67709 Homo sapiens mRNA full length insert cDNA clo 4.7
441421 AA356792 Hs.334824 hypothetical protein FU14825 4.7
457465 AW301344 Hs.122908 DNA replication fxtor 4.6
433159 AB035898 Hε.150587 kineεin-like protein 2 4.6
412333 AW937485 gb:QV3-DT0044-221299-045-b09 DT0044 Homo sapi 4.6
401137 Target Exon 4.6
401575 Target Exon 4.6
423448 AK000776 Hs.128753 Homo sapiens cDNA FU20769 fis, clone COL0667 4.6
421978 AJ243662 Hs.110196 NICE-1 protein 4.6
408728 AL137379 Hs.47125 hypothetical protein FU13912 4.6
431956 AK002032 Hs.272245 Homo sapiens cDNA FLJ11170 fis, clone PLACE10 4.6
450510 AA010056 Hs.242998 ESTs 4.6
436291 BE568452 Hs.5101 protein regulator of cytokinesis 1 4.6
424902 NM.003866 Hs.153687 inositol polyphosphate4-phosphataεe, type II 4.6
428484 AF104032 Hs.184601 εolute carrier family 7 (cationic amino xid 4.5
449416 AI651016 Hs.246311 ESTs 4.5 416168 H23687 gb yn72d12 r1 Soares adult brain N2b5HB55Y Ho 45
447033 AI357412 Hs 157601 ESTs 45
446353 AI290919 Hs 153661 ESTs 45
443715 AI583187 Hs 9700 cyclm E1 45
454707 AW814989 gb MR1-ST0206-170400 024-g05 ST0206 Homo sapi 45
435435 T89473 Hs 192328 ESTs 45
412099 U64198 Hs 73165 interleukin 12 rxeptor, beta 2 44
409731 AA125985 Hs 56145 thymosm, beta identified in neurablastoma c 44
422809 AK001379 Hs 121028 hypothetical protein FU 10549 44
430919 AA489041 Hs 295448 ESTs 44
435313 AI769400 Hs 189729 ESTs 44
425071 NM 013989 Hs 154424 deiodinase, lodothyroπiπe, type II 44
433322 H50621 Hs 134156 ESTs, Weakly similar to I38022 hypothetical p 44
416111 AA033813 Hs 79018 chromatin aεεembly fxtor 1, εubunitA (p150) 44
408908 BE296227 Hs 250822 εeπne/threonme kinase 15 44
444781 NM 014400 Hs 11950 GPI anchored metastaεiε-aεε∞iated protein ho 44
429170 NM 001394 Hε 2359 dual specificity phosphatase 4 44
414035 Y00630 Hs 75716 seπne (or cysteine) proteinaεe inhibitor, cl 44
418216 AA662240 Hs 283099 AF15q14 protein 44
446252 AI283125 Hs 150009 ESTs 44
447519 U46258 Hs 339665 ESTs 44
425916 NM.006786 Hs 162200 urotensin 2 43
409420 Z15008 Hs 54451 laminin, gamma 2 (nicem (100kD), kalin (10 43
416320 H47867 Hs 34024 ESTs 43
431808 M30703 Hs 270833 amphiregulin (schwannoma deπved growth fxto 43
441582 BE550200 Hs 127197 ESTs 43
414132 AI801235 Hs 48480 ESTs 43
424012 AW368377 Hs 137569 tumor protein 63 kDa with strong homology to 43
411835 U29343 Hs 72550 hyaluronan mediated motility receptor (RHAMM) 43
433330 AW207084 Hs 132816 hypothetical protein MGC14801 43
428613 AB037749 Hs 186928 KIAA1328 protein 43
425921 NM 007231 Hs 162211 solute earner family 6 (πeurotraπsmitter tra 43
447078 AW885727 Hs 301570 ESTs 43
434699 AA643687 Hs 149425 Homo sapienε cDNA FU11980 fis, clone HEMBB10 43
428758 AA433988 Hs 98502 hypothetical protein FU 14303 43
405708 Target Exon 43
433405 AW157566 Hs 156892 ESTs 43
456443 AW967500 Hs 133543 ESTs 43
428479 Y00272 Hs 184572 cell division cycle 2, G1 to S and G2 to M 42
448621 AI097144 Hs 5250 ESTs, Weakly similarto ALU1.HUMAN ALU SUBFAM 42
412608 AA247995 Hs 44898 Homo sapienε clone TCCCTA00151 mRNA εequence 42
406687 M31126 Hs 272620 pregnancy spxific beta-1-glycoproteιn 9 42
455365 AW948343 gb RC0-MT0015-130400-031-C01 MT0015 Homo sapi 42
452930 AW195285 Hs 194097 ESTs, Weakly similar to I38022 hypothetical p 42
430134 BE380149 Hs 105223 ESTs, Weakly similar to T33188 hypothetical p 42
423035 AW449679 Hs 156739 H sapienε XG mRNA (clone PEP11) 42
427666 AI791495 Hs 180142 calmedulin-like skin protein 42
444602 AI174456 Hs 271925 ESTs, Moderately similar to I38022 hypothetic 42
417791 AW965339 Hs 111471 ESTs 42
444266 AI424984 Hs 125465 ESTs 42
439394 AA149250 Hs 56105 ESTs 42
457336 AW969657 Hs 291029 ESTs 42
429125 AA446854 Hs 271004 ESTs, Weakly similar to I38022 hypothetical p 42
404440 NM.021048 Homo sapienε melanoma antigen, fami 42
449228 AJ403107 Hs 148590 protein related with psoriasis 42
437144 AL049466 Hs 7859 ESTε 42
448599 AW860912 gb QVO-CT0387-170200-121-C05 CT0387 Homo sapi 42
431810 X67155 Hs 270845 kinesm like 5 (mitotic kinesm like protein 42
419991 AJ000098 Hs 94210 eyes abεent (Drasophila) homolog 1 42
444361 W76027 Hs 23920 hypothetical protein FU11105 42
458116 AW977549 Hs 47367 KIAA1785 protein 41
444105 AW189097 Hs 166597 ESTs 41
426010 AA136563 Hs 1975 hypothetical protein FU21007 41
409632 W74001 Hs 55279 senne (or cysteine) proteinase inhibitor, cl 41
408096 BE250162 Hs 83765 dihydrofolate reductase 41
457620 AA602711 Hs 336753 EST 41
402048 Target Exon 41
427025 AA397589 Hs 97523 ESTs 41
423515 AA327017 Hs 162204 ESTs 41
423891 AK002042 Hs 134795 Homo sapiens cDNA FU 11180 fis, clone PLACE10 41
455310 AW893961 gb RC4-NN0027-060400-011-d11 NN0027 Homo sapi 41
418696 AW959433 Hs 326290 hypothetical protein FU12581 41
426642 AW068223 Hs 171581 ubiquitin C-terminal hydrolase UCH37 41
423738 AB002134 Hs 132195 airway trypsin like protease 41
448243 AW369771 Hs 52620 integπn, beta 8 4 1
411559 BE144081 gb MRO-HT0165-030200-007-d06 HT0165 Homo sapi 41
423553 AA405635 Hs 96854 ESTs, Weakly similar to DYLX.HUMAN CYTOPLASMI 41
457030 AI301740 Hs 173381 dihydropyπmidinase-like 2 41
424115 AA335497 Hs 293965 ESTs, Weakly similar to I38022 hypothetical p 41
432374 W68815 Hs 301885 Homo sapiens cDNA FU 11346 fis, clone PLACE10 41
424745 AA214618 Hs 152759 xtivator of S phase kinase 40
433384 AI021992 Hε 124244 ESTs 40
448995 AI613276 Hs 5662 guanine nucleotide binding protein (G protein 40 448504 AI858128 Hs 171136 ESTs 40
432009 AL137424 Hs 306458 Homo sapiens mRNA cDNA DKFZp761G21 3 (from c 40
432441 AW292425 Hs 163484 ESTs 40
424794 M85646 Hs 210696 ESTs 40
432184 AW971125 gb EST383212 MAGE resequences MAGL Homo sapi 40
408321 AW405882 Hs 44205 cortistatm 40
417801 AA417383 Hs 82582 integπn, beta-like 1 (with EGF like repeat d 40
445537 AJ245671 Hs 12844 EGF-like-domam, multiple 6 40
447724 AW298375 Hε 24477 ESTs 40
446155 AI553695 Hs 159422 Homo sapiens cDNA FLJ13997 fis, clone Y79AA10 40
446989 AK001898 Hs 16740 hypothetical protein FU11036 40
420252 AW270404 Hε 193161 ESTs 40
412811 H06382 Hε 21400 ESTs 40
415857 AA866115 Hs 127797 Homo sapiens cDNA FU11381 fis, clone HEMBA10 40
438390 AI422017 gb tf45f12x1 NCI_CGAP_Brn23 Homo sapiens cDN 40
428949 AA442153 Hs 104744 hypothetical protein DKFZp434J0617 40
429900 AA460421 Hs 30875 ESTs 40
421270 H56037 Hs 108146 ESTs 39
430733 AW975920 Hs 283361 ESTs 39
454241 BE144666 gb CM2-HT0176-041099 017-c02 HT0176 Homo sapi 39
424131 AA335714 Hs 199665 ESTs 39
457059 BE561665 Hs 177677 exosome component Rrp40 39
424717 H03754 Hs 152213 wingless type MMTV integration site family, m 39
404959 NM.025001* Homo sapiens hypothetical protein 39
411571 AA122393 Hs 70811 hypothetical protein FU20516 39
428536 AI143139 Hs 2288 vismin like 1 39
426830 AA385751 Hs 196379 ESTs, Weakly similar to putative p150 [H sapi 39
432757 AF113013 Hs 278919 PRO0806 protein 39
418686 Z36830 Hs 87268 annexin A8 39
437845 AA769578 Hs 90488 ESTs 39
413801 M62246 Hs 35406 ESTε, Highly similar to unnamed protein pradu 39
419312 AA831850 Hs 58149 hypothetical protein MGC14136 39
429441 AJ224172 Hs 204096 lipophilm B (uteroglobin family member), pro 39
410553 AW016824 Hs 255527 hypothetical protein MGC14128 39
444665 BE613126 Hs 47783 B aggressive lymphoma gene 39
438014 N71183 Hs 121806 Homo sapiens cDNA FU11971 fis, clone HEMBB10 39
442163 AI791749 Hs 128896 ESTε 39
438656 H85310 Hs 209456 ESTs, Weakly similar to NG22 [H sapienε] 39
406560 ENSP00000016943* CDNA 38
407395 AF005082 gb Homo εapienε skin spxific protein (xp33) 38
404132 Target Exon 38
409601 AF237621 Hs 80828 keratin 1 (epidermolytic hyperkeratosis) 38
439238 N47305 Hs 46668 ESTs 38
433289 AF005258 gb Homo sapiens laminin alpha 3b chain mRNA, 38
436149 AI754308 Hε 159452 ESTs 38
446292 AF081497 Hs 279682 Rh type C glycoprotein 38
444078 BE246919 Hs 10290 U5 snRNP-εpxific 40 kDa protein (hPrpβ-bmdi 38
405545 (MDR TAP) (TAP2) 38
442875 BE623003 Hs 23625 Homo εapienε clone TCCCTA00142 mRNA εequence 38
409687 T51125 Hs 8493 ESTs 38
407291 AA001464 gb ze45b01 r1 Soares retina N2b4HR Homo sapie 38
415532 R14780 Hε 12826 ESTε 38
402047 AK001921 Hε 169575 hypothetical protein MGC2550 38
415317 Z43388 gb HSC1AF121 normalized infant brain cDNA Hom 38
438777 AA825487 Hε 142179 ESTε 38
422938 NM.001809 Hs 1594 centromere protein A (17kD) 37
423217 NM.00009'! 1 Hε 1640 collagen, type VII, alpha 1 (epidermolyεiε bu 37
405943 Target Exon 37
430686 NM 001942 Hs 2633 deεmoglein 1 37
458242 BE299588 Hs 28465 Homo sapiens cDNA FU21869 fis, clone HEP024 37
425733 F13287 Hs 159388 Homo sapienε clone 23578 mRNA εequence 37
418582 BE244318 Hs 213194 hypothetical protein MGC10895 37
453900 AW003582 Hs 226414 ESTε, Weakly similar to ALU8.HUMAN ALU SUBFAM 37
433849 BE465884 Hs 280728 ESTs 37
449592 AI655494 Hs 195718 ESTs 37
453028 AB006532 Hs 31442 RxQ protein like 4 37
435612 AA693537 Hs 321411 ESTs 37
417742 R64719 gb EST22d11 WATM1 Homo sapiens cDNA clone 22d 37
418735 N48769 Hε 44609 ESTs 37
444707 AI188613 Hs 41690 desmocollin 3 37
421508 NM.004833 Hs 105115 absent in melanoma 2 37
450613 AI702055 gb tq20g10 x1 NCI.CGAP.Ut1 Homo sapiens cDNA 37
418969 W33191 Hs 28907 hypothetical protein FU20258 37
432837 AA310693 Hs 87329 HSPC072 protein 37
442353 BE379594 Hs 49136 ESTs, Moderately similar to ALU7.HUMAN ALU SU 37
423441 R68649 Hs 278359 absent in melanoma 1 like 37
449978 AI806335 Hs 200829 ESTs, Weakly similar to T30171 πinem - mouse 37
410784 AW803201 gb IL2-UM0077-070500-080-E06 UM0077 Homo sapi 37
409582 R27430 Hs 271565 ESTs 36
428182 BE386042 Hs 293317 ESTs, Weakly similar to GGC1.HUMAN G ANTIGEN 36
458446 AW394104 Hε 43744 ESTs, Moderately similar to I54374 gene NF2 p 36
433040 H70423 Hs 300511 ESTs 36
452193 AA987351 Hs 184993 ESTs 36 408771 AW732573 Hs.47584 potassium voltage-gated channel, delayed-rxt 3.6
440046 AW402306 Hs.6877 hypothetical protein FU10483 3.6
459575 BE080825 gb:QV1-BT0631-180200-078-c08 BT0631 Homo sapi 3.6
400441 M15530 Hs.99879 B-cell growth fxtor 1 (12kD) 3.6
440138 AB033023 Hs.318127 hypothetical protein FLJ10201 3.6
417830 AW504786 Hs.122579 hypothetical protein FU10461 3.6
427131 AA448460 Hs.112017 GE36 gene 3.6
413278 BE563085 Hs.833 interferon-stimulated protein, 15 kDa 3.6
420373 AW968228 gb:EST380198 MAGE resequences, MAGJ Homo sapi 3.6
414136 AA812434 Hs.119023 SMC2 (structural maintenance of chromosomes 2 3.6
424296 AI631874 Hs.155140 casein kinase 2, alpha 1 polypeptide 3.6
424639 AI917494 Hs.9812 Homo sapienε cDNA FU14388 fiε, clone HEMBA10 3.6
419196 AF110908 Hs.297660 TNF receptor-assxiated fxtor 3 3.6
434321 AA629368 gb:zu78a11.s1 Soareε.teεtiε.NHT Homo εapieπs 3.6
426514 BE616633 Hε.170195 bone orphogenetic protein 7 (osteogeπic prot 3.6
427335 AA448542 Hs.251677 G antigen 7B 3.6
413472 BE242870 Hs.75379 solute carrier family 1 (glial high affinity 3.6
408000 L11690 Hε.620 bullous pemphigoid antigen 1 (230/240kD) 3.6
426749 AI623718 Hs.105618 ESTs 3.6
443899 AW842283 Hs.79933 cyclin I 3.6
440684 AI253123 Hs.127356 ESTs.'Highly εimilar to S21424 neεtin [H.εapi 3.6
424927 AW973666 Hs.153850 hypothetical protein C321D2.4 3.6
408591 AF015224 Hs.46452 mammaglobiπ 1 3.5
408867 AA437199 Hs.656 cell division cycle 25C 3.5
428508 BE252383 Hs.184668 SBBI31 protein 3.5
431120 AA492588 gb:ng99c08.s1 NCI.CGAP.Thy1 Homo sapiens cDNA 3.5
401780 NM_005557*:Homo sapfens keratin 16 (focal non 3.5
409695 AA296961 gb:EST112514 Adrenal gland tumor Homo sapfens 3.5
456671 AB011142 Hs.114293 KIAA0570 gene product 3.5
412155 R38167 Hs.12449 Homo sapfens transmembrane protein HTMP10 (HT 3.5
435244 N77221 Hs.187824 ESTs 3.5
436246 AW450963 Hs.119991 ESTs 3.5
431917 D16181 Hs.2868 peripheral myelin protein 2 3.5
443113 AI040686 Hs.132908 ESTs 3.5
443341 AW631480 Hs.8688 ESTs 3.5
407756 AA116021 Hs.38260 ubiquitin spxific protease 18 3.5
418347 AA216419 gb:nc16e03.s1 NCI CGAP Pr1 Homo sapfens cDNA 3.5
423841 AW753967 gb:RC2-CT0304-080100-011-h12 CT0304 Homo sapi 3.5
408633 AW963372 Hs.46677 PRO2000 protein 3.5
427878 C05766 Hs.181022 CGI-07 protein 3.5
419945 AW290975 Hs.118923 ESTs 3.5
448372 AW445166 Hs.170802 ESTs 3.5
407137 T97307 gb:ye53h05.ε1 Soareε fetal liver εpleen 1 NFLS 3.5
411274 NM.002776 Hs.69423 kallikrein 10 3.5
400666 NM_002425:Homo sapiens matrix metalloproteina 3.5
426920 AA393351 Hs.132121 ESTs 3.5
402639 Target Exon 3.4
454891 AW837349 gb:QV2-LT0038-270300-108-d12 LT0038 Homo sapi 3.4
412471 M63193 Hs.73946 endothelial cell growth fxtor 1 (platelet-de 3.4
456296 AA829976 Hs.239114 manπosidase, alpha, class 1A, member 2 3.4
450650 T65617 Hs.101257 hypothetical protein MGC3295 3.4
429274 AI379772 Hs.99206 ESTs 3.4
430704 AW813091 Hs.335799 ESTs 3.4
419807 R77402 gb:yi75f11.s1 Soareε plxenta Nb2HP Homo sapi 3.4
451778 AI826131 Hs.71243 ESTs, Weakly similar to zinc finger protein ( 3.4
430397 AI924533 Hs.105607 bicarbonate transporter related protein 1 3.4
432113 AA935065 Hs.152385 ESTs 3.4
449722 BE280074 Hs.23960 cyclin B1 3.4
455092 BE152428 gb:CMO-HT0323-151299-126-b04 HT0323 Homo sapi 3.4
418203 X54942 Hs.83758 CDC28 protein kinase 2 3.4
453775 NM_0029ie i Hs.35120 replication fxtor C (activator 1) 4 (37kD) 3.4
417009 AA191719 Hs.314714 ESTs 3.4
444743 AA045648 Hs.301957 nudix (nucleoside diphosphate linked moiety X 3.4
434206 AW136973 Hs.288516 ESTs, Weakly similar to S69890 mitogen induci 3.4
413219 AA878200 Hs.118727 Homo sapiens cDNA FU13692 fis, clone PLACE20 3.4
422487 AJ010901 Hs.198267 mucin 4, trxheobranchial 3.4
438993 AA828995 gb:od77b08.s1 NCI_CGAP_Ov2 Homo sapiens cDNA 3.4
403274 Target Exon 3.4
435360 AF105366 Hs.4876 solute carrier family 12 (potassium/chloride 3.4
426572 AB037783 Hs.170623 hypothetical protein FU11183 3.4
432615 AA557191 Hs.55028 ESTs, Weakly similar to 154374 gene NF2 prate 3.4
443462 AI064690 Hs.171176 ESTs 3.3
444910 AI201849 gb:qs76g04.x1 NCI_CGAP_Pr28 Homo sapiens cDNA 3.3
426269 H15302 Hs.168950 Homo sapienε mRNA; cDNA DKFZp566A1046 (from c 3.3
449101 AA205847 Hs.23016 G protein-coupled rxeptor 3.3
418994 AA296520 Hs.89546 εelxtin E (endothelial adhesion molxule 1) 3.3
427660 AI741320 Hs.114121 Homo sapiens cDNA: FU23228 fis, clone CAE066 3.3
419751 AW195581 Hε.93121 KIAA0761 protein 3.3
404782 C7001692*:gi|6724096|gb|AAF26844.1| (AF195021 3.3
415613 R20233 gb:yg18h11.r1 Soares infant brain 1NIB Homo s 3.3
452198 AI097560 Hs.61210 ESTε, Weakly εimilar to I38022 hypothetical p 3.3
406599 Target Exon 3.3
433001 AF217513 Hs.279905 clone HQ0310 PRO0310p1 3.3 412879 BE092219 gb IL2 BT0734-240400-071-B04 BT0734 Homo sapi 33
421107 AA283822 Hs 55606 ESTs, Weakly similar to S47072 finger protein 33
436985 AA740946 Hs 150895 ESTs 33
443903 AI220547 Hs 135223 ESTs 33
432015 AL157504 Hs 159115 Homo sapienε mRNA cDNA DKFZp586O0724 (from c 33
447153 AA805202 Hs 315562 ESTε 33
450769 AA057418 Hs 33654 ESTs 33
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cys X C 33
402481 NM.001821* Homo sapiens choroideremia-like (R 33
459394 BE409894 Hs 126522 Homo sapiens, clone MGC 16722 mRNA, complete 33
424364 AW383226 Hs 201189 ESTs, Weakly similar to G01763 atrophιn-1 [H 33
417708 N74392 Hs 50495 ESTs 33
414869 AA157291 Hs 21479 ubinuclein 1 33
441690 R81733 Hs 33106 ESTs 33
414774 X02419 Hs 77274 plasmmogen xtivator, urakmase 33
412246 AI160873 Hs 69233 zinc finger pratem 33
412903 BE007967 Hs 155795 ESTs 33
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (plxental) 33
451177 AI969716 Hs 13034 ESTs 33
409990 AA079337 gb zm95b09 r1 Stratagene colon HT29 (937221) 33
418462 BE001596 Hs 85266 integnn, beta 4 33
424687 J05070 Hs 151738 matnx metalloproteinase 9 (gelat ase B, 92k 33
405196 C2000662* gι|7512792|pιr||T12482 hypothetical 33
459267 AJ003631 gb AJ003631 Selxted chromosome 21 cDNA libra 33
432917 NM 014125 Hs 279812 PRO0327 protein 33
448251 BE280486 Hs 84045 hypothetical protein FLJ20288 33
415025 AW207091 Hs 72307 ESTs 33
420218 AW958037 Hs 286 nbosomal protein L4 32
429594 AK001128 Hs 210297 Homo εapiens cDNA FLJ10266 fis clone HEMBB10 32
447762 AI939461 Hs 161370 ESTs 32
414147 BE091634 gb IL2 BT0731 240400 069 C03 BT0731 Homo sapi 32
445038 AI635444 Hs 143917 dJ467N11 1 protein 32
448666 NM.014953 Hs 323346 KIAA1008 protein 32
402800 Target Exon 32
411263 BE297802 Hs 69360 kines like 6 (mitotic centromere-ass∞iated 32
424308 AW975531 Hs 154443 mmichromoεome maintenance deficient (S cere 32
455203 AW865450 gb PM4-SN0020-010400-008-b09 SN0020 Homo εapi 32
459666 W27362 gb 30g7 Human retina cDNA randomly pπmed sub 32
401458 Target Exon 32
432361 AI378562 Hs 159585 ESTs 32
444008 BE544855 Hs 220756 ESTs, Weakly similarto SFR4.HUMAN SPLICING F 32
405336 Target Exon 32
446563 BE326588 Hs 141454 ESTε 32
449276 AW241510 Hs 252713 ESTε 32
455838 BE145808 gb MR0-HT0208 101299-103-f 11 HT0208 Homo sapi 32
420591 X53655 Hs 99171 neurotraphin 3 32
401486 C4000647* gι|4758508|ref|NP 004253 1| airway 32
432979 AA573263 Hε 120860 ESTs 32
413833 Z15005 Hε 75573 centromere pratem E (312kD) 32
438325 AA804258 Hs 123229 ESTs 32
421751 AW813731 Hs 159153 ESTs, Moderately similar to S65657 alpha-1C-a 32
431938 AA938471 Hs 54431 spxific granule protein (28 kDa), cysteine-r 32
421777 BE562088 Hs 108196 HSPC037 protein 32
408113 T82427 Hs 194101 Homo εapiens cDNA FU20869 fis, clone ADKA02 32
427359 AW020782 Hε 79881 Homo sapiens cDNA FU23006 fis, clone LNG004 32
402337 Target Exon 32
420930 AW888650 gb CM4-NT0007-130500-551-f06 NT0007 Homo sapi 32
436168 AK000883 Hε 301645 Homo sapiens cDNA FU10021 fis, clone HEMBA10 32
443426 AF098158 Hε 9329 chromosome 20 open reading frame 1 31
437641 AA811452 Hs 291911 ESTε 3 1
414761 AU077228 Hs 77256 enhancer of zeεte (Drasophila) homolog 2 31
434208 T92641 Hs 127648 hypothetical protein PR02176 31
433222 AW514472 Hs 238415 ESTε, Moderately similar to ALU8.HUMAN ALU SU 31
452934 AA581322 Hs 4213 hypothetical protein MGC16207 31
458923 Y12812 Hs 24422 regulatory fxtor X assxiated protein 31
448988 Y09763 Hs 22785 gamma-aminobutyπc xid (GABA) A rxeptor, ep 31
439750 AL359053 Hs 57664 Homo sapienε mRNA full length insert cDNA clo 31
422283 AW411307 Hs 114311 CDC45 (cell division cycle 45, S cerevisiae, 31
445885 AI734009 Hs 127699 KIAA1603 protein 31
441962 AW972542 Hs 289008 Homo sapiens cDNA FU21814 fis, clone HEP010 31
424653 AW977534 Hs 151469 calcium/calmodulin-dependent senne protein k 31
431322 AW970622 gb EST382704 MAGE resequences, MAGK Homo sapi 31
423934 U89995 Hs 159234 forkhead box E1 (thyroid transcnption fxtor 31
455987 BE178323 gb RC3-HT0600-240400-023fl05 HT0600 Homo sapi 3 1
421426 AA291101 Hs 33020 Homo εapiens, clone IMAGE 3939163, mRNA, part 31
423887 AL080207 Hs 134585 DKFZP434G232 protein 31
408296 AL117452 Hs 44155 DKFZP586G1517 protein 31
447815 AI432199 Hs 247084 ESTs 3 1
441974 AI683782 Hs 128245 ESTs 31
446474 AI301227 Hs 150186 hypothetical protein DKFZp566K1946 31
452166 AI948607 Hs 264680 ESTs 31
451659 BE379761 Hs 14248 ESTs 3 1
439979 AW600291 Hs 6823 hypothetical protein FU10430 3 1 447701 BE619526 Hs 255527 hypothetical protein MGC14128 31
443648 AI085377 Hs 143610 ESTs 31
414696 AF002020 Hs 76918 Niemann Pick disease, type C1 31
449441 AI656040 Hs 196532 ESTs 31
458145 AI239457 Hs 130794 ESTs 31
444588 AI221321 Hs 167559 ESTs 31
450832 AW970602 Hs 105421 ESTs 31
449425 AW103433 Hs 195684 ESTs 31
440953 AI683036 Hs 124135 Homo sapiens cDNA FLJ13051 fis, clone NT2RP30 31
422158 L10343 Hs 112341 proteaεe inhibitor 3, skin-deπved (SKALP) 3 1
416120 H46739 gb yo14h02 s1 Soareε adult brain N2b5HB55Y Ho 3 1
425081 X74794 Hs 154443 minichromosome maintenance deficient (S cere 31
404107 Target Exon 3 1
419563 AA526235 Hs 193162 Homo sapiens cDNA FU11983 fis, clone HEMBB10 31
417168 AL133117 Hs 81376 Homo sapiens mRNA, cDNA DKFZp586L1121 (from c 31
435604 AA625279 Hs 26892 uncharacteπzed bone marrow protein BM040 3 1
442824 BE178065 Hs 144081 ESTs 3 1
435061 AI651474 Hs 163944 ESTs 3 1
420589 AA419360 Hs 192708 ESTs 30
434569 AI311295 Hs 8294 KIAA0196 gene product 30
420039 NM.004605 Hs 94581 sulfotransferase family cytosolic, 2B, membe 30
453883 AI638516 Hs 22630 cofactor required for Sp1 transcnptional xt 30
402892 Target Exon 30
406087 Target Exon 30
411770 NM.014278 Hs 71992 heat εh∞k protein (hεpl 10 family) 30
459587 AA031956 gb zk15e04 ε1 Soares_pregnanLuterus NbHPU Ho 30
435990 AI015862 Hs 131793 ESTs 30
442577 AA292998 Hs 163900 ESTs 30
448733 NM 005628 Hε 187958 solute earner family 6 (neurotransmitter tra 30
458154 AW816379 Hs 335018 ESTs 30
416809 N67253 Hs 271691 ESTs 30
444946 AW139205 Hs 156457 hypothetical protein FU22408 30
437938 AI950087 gb wq05c02 x1 NCI_CGAP_Kιd12 Homo sapiens cDN 30
413281 AA861271 Hs 222024 transcnption fxtor BMAL2 30
434808 AF155108 Hs 256150 Homo sapiens, Similar to RIKEN cDNA 281002701 30
445505 AI971156 Hs 148891 ESTs 30
425005 AI565851 gb tn07g03 x1 NCI_CGAP_Brn25 Homo sapiens cDN 30
435673 AF202961 Hε 284200 Homo sapiens uncharxteπzed gastric protein 30
432189 AA527941 gb nh30c04 s1 NCI_CGAP_Pr3 Homo sapiens cDNA 30
453509 AL040021 Hs 252674 ESTs, Weakly similar to alternatively spliced 30
455750 BE075114 gb PM1-BT0585-110200-003-C11 BT0585 Homo sapi 30
407777 AA161071 Hs 71465 squalene epoxidase 30
424441 X14850 Hs 147097 H2A histone family, member X 30
417734 Z42667 Hs 6724 ESTs 30
449676 AW380579 Hs 209657 ESTs 30
445425 AI223511 Hs 300722 ESTε 30
427061 AB032971 Hs 173392 KIAA1145 protein 30
433584 AW295399 gb Ul-H BI2-ahv-h 03-0-UI ε1 NCI CGAP_Sub4 Ho 30
444477 AI150548 Hs 23155 ESTs 30
446255 AI283257 Hs 257090 ESTs 30
400612 C10001034gι|7513113|pιr||T13078 KIAA0992 pro 30
450841 AI741466 Hs 270515 ESTs 30
410561 BE540255 Hs 6994 Homo sapiens cDNA. FU22044 fis, done HEP091 30
433871 W02410 Hs 205555 ESTs 30
401994 Target Exon 30
449272 AW137656 Hs 197645 ESTε 30
409703 NM.00618 ' Hs 56009 2'-5'-olιgoadenylate εynthetaεe 3 (100 kD) 30
400250 Eos Control 30
408015 AW136771 Hs 244349 epidermal differentiation complex protein lik 30
436414 BE264633 Hs 143638 WD repeat domain 4 30
432220 AI571306 Hs 232224 ESTs 30
420831 AA280824 Hs 190035 ESTs 30
433644 AW342028 gb hb75d03 x1 NCI_CGAP_Ut2 Homo sapiens cDNA 30
447313 U92981 Hs 18081 Homo sapiens clone DT1P1B6 mRNA, CAG repeat r 30
428262 AI651324 Hs 7298 biphenyl hydrolaεe-like (seπne hydrolase, br 30
452778 R71338 Hs 5921 Homo sapiens cDNA FU21592 fis, clone COL070 30
417308 H60720 Hs 81892 KIAA0101 gene product 30
436281 AW411194 Hs 85195 myeloid leukemia fxtor 1 30
433485 AI493076 Hs 201967 aldo-keto reductase family 1 , member C2 (dihy 30
423556 R72694 Hs 7720 dynem, cytoplasmic, heavy polypeptide 1 30
426890 AA393167 Hε 41294 ESTs 29
436333 AA709270 Hs 136672 EST 29
440006 AK000517 Hs 6844 hypothetical protein FU20510 29
402556 C1001383* gι|538695|pιr||A61183 hypothetical 29
411098 AW817238 gb QVO-ST0247-090200-105-b07 ST0247 Homo sapi 29
435399 AA679463 gb x50c03 s1 Stratagene hNT neuron (937233) 29
431070 AW408164 Hε 249184 transcnption fxtor 19 (SC1) 29
427986 N45214 Hs 282387 Homo sapiens cDNA FU21837 fis, clone HEP016 29
410658 AW105231 Hs 192035 ESTs 29
434539 AW748078 Hs 214410 ESTs, Weakly similar to MUC2 HUMAN MUCIN 2 PR 29
412279 BE245511 gb TCBAP1D3235 Pediatnc pre-B cell xute lym 29
405277 ENSP00000211621* Keratin, type II cytoskeleta 29
423733 AA330281 gb EST33985 Embryo, 12 week II Homo εapiens c 29 455319 AW895387 gb:QV4-NN0038-300300-157-c10 NN0038 Homo sapi 2.9
407638 AJ404672 Hs.334483 hypothetical protein FLJ23571 2.9
413306 AW303544 Hs.118654 ESTs 2.9
432215 AU076609 Hs.2934 ribonucleotide reductase M1 polypeptide 2.9
434423 NM 006769 Hs.3844 UM domain only 4 2.9
446269 AW263155 Hs.14559 hypothetical protein FU 10540 2.9
412367 AW945964 gb:QVO-ET0001-050500-228-e09 ET0001 Homo sapi 2.9
436148 BE005252 Hε.321583 Homo sapiens cDNA FU20779 fis, clone COL0507 2.9
421190 U95031 Hs.102482 mucin 5, subtype B, trxheobroπchial 2.9
404981 ENSP00000252242*:Keratin, type II cytoskeleta 2.9
448796 AA147829 Hs.301431 endothelial zinc finger protein induced by tu 2.9
452732 BE300078 Hs.80449 Homo sapiens, clone IMAGE:3535294, mRNA, part 2.9
401760 Target Exon 2.9
443859 NM.013409 Hε.9914 follistatiπ 2.9
404253 NM.021058*:Homo sapiens H2B histone family, m 2.9
432491 AA662910 Hs.42635 hypothetical protein DKFZp434K2435 2.9
435867 AA954229 Hs.114052 ESTs 2.9
429035 BE549781 Hs.270475 ESTs 2.9
446733 AA863360 Hs.26040 ESTs, Weakly similar to fatty xid omega-hydr 2.9
446417 AI299050 gb:qn14d12.x1 NCI.CGAP.Lu5 Homo εapienε cDNA 2.9
437637 AJ003029 Hs.65792 syntrophin, gamma 2 2.9
452452 BE393822 Hs.29645 Homo sapiens mRNA; cDNA DKFZp761 C029 (from cl 2.9
442432 BE093589 Hs.38178 hypothetical protein FLJ23468 2.9
450698 W31489 Hs.95044 ESTs, Weakly similar to I38022 hypothetical p 2.9
439430 AF124250 Hs.6564 cervical cancer anti-estrogen reεiεtance 3 2.9
434876 AF160477 Hs.61460 Ig superfamily rxeptor LNI R 2.9
438268 AA782163 Hs.293502 ESTs 2.9
401781 Target Exon 2.9
439625 AF086453 Hs.58611 ESTs 2.9
425234 AW152225 Hs.165909 ESTs, Weakly similar to I38022 hypothetical p 2.9
410743 AA089474 Hs.272153 ESTs 2.9
414915 NM.002462 Hs.76391 myxovirus (influenza) reεistance 1 , homolog o 2.9
449746 AI668594 Hs.176588 ESTε, Weakly similar to CP4Y.HUMAN CYTOCHROME 2.9
443479 AF027219 Hs.9443 zinc finger protein 202 2.9
442601 AI684969 Hs.46772 ESTs 2.9
405932 C15000305:gi|3806122|gb|AAC69198.1| (AF097887 2.9
405454 C12000541:gi|5729884|ref|NP_006539.1| IGF-II 2.9
418844 M62982 Hs.1200 arachidonate 12-lipoxygenase 2.9
408562 AI436323 Hs.31141 Homo εapienε mRNA for KIAA1568 protein, parti 2.9
408829 NM.006042 Hs.48384 heparan sulfate (glucosamine) 3-0-sulfotransf 2.9
414581 AA256213 Hs.72010 ESTs 2.9
411268 AK000512 Hs.69388 hypothetical protein FU20505 2.9
450024 AA005129 gb:zh90h08.r1 Soares_fetal_liver_spleen_1NFLS 2.9
400297 AI127076 Hs.334473 hypothetical protein DKFZp56401278 2.9
436481 AA379597 Hs.5199 HSPC150 protein similar to Ubiquitin-conjugat 2.9
400631 AF173937 Hs.109494 sxreted protein of unknown function 2.9
429118 H20669 Hs.35406 ESTs, Highly similar to unnamed protein produ 2.9
444381 BE387335 Hs.283713 ESTs, Weakly similar to S64054 hypothetical p 2.9
435711 AF226667 Hs.58553 CTP synthase II 2.9
419088 AI538323 Hs.52620 integnn, beta 8 2.8
431629 AU077025 Hε.265827 interferon, alpha-inducible protein (clone IF 2.8
429299 AI620463 Hs.293984 hypothetical protein MGC13102 2.8
451702 AW665452 Hs.246503 ESTs 2.8
432162 AA584062 Hs.272798 hypothetical protein FU20413 2.8
405281 NM_002864:Homo sapienε pregnancy-zone protein 2.8
438161 BE089028 Hs.20158 ESTs, Weakly similar to S34159 transcription 2.8
409103 AF251237 Hs.112208 XAGE-1 protein 2.8
425599 AW366745 Hs.214140 ESTs, Weakly similarto ALU1.HUMAN ALU SUBFAM 2.8
425274 BE281191 Hs.155462 minichromosome maintenance deficient (mis5, S 2.8
435099 AC004770 Hs.4756 flap structure-spxific endonuclease 1 2.8
445873 AA250970 Hs.251946 poly(A)-binding protein, cytoplasmic 1-like 2.8
452730 AA027952 Hε.165216 ESTs 2.8
413083 BE064528 gb:RC4-BT0311-250200-014-h06 BT0311 Homo sapi 2.8
437030 AA742577 Hε.303781 EST 2.8
438113 AI467908 Hε.8882 ESTs 2.8
442973 BE567665 Hs.288550 Homo sapiens cDNA: FU23156 fis, clone LNG096 2.8
440994 AI160011 Hε.193341 ESTs 2.8
442295 AI827248 Hs.224398 Homo sapiens cDNA FU 11469 fiε, clone HEMB A10 2.8
422689 AW856665 gb:RC3-CT0297-290100-013-d03 CT0297 Homo sapi 2.8
410310 J02931 Hs.62192 coagulation fxtor III (thromboplastin, tiεsu 2.8
424408 AI754813 Hε.146428 collagen, type V, alpha 1 2.8
433788 AI810534 Hs.161275 ESTs 2.8
403806 Target Exon 2.8
437182 AL080098 gb:Homo sapiens mRNA; cDNA DKFZp564C1072 (fro 2.8
453955 AW579207 Hs.304666 ESTs, Weakly similar to I78885 εerine/threoni 2.8
420795 AA323037 Hs.128645 sorting nexin 16 2.8
452696 AI826645 Hs.211534 ESTs 2.8
432656 NM.000246 Hs.3076 MHC class II transxtivator 2.8
438052 AA776564 Hs.41891 zinc finger 1111 2.8
441755 AW450826 Hs.127786 ESTs 2.8
427961 AW293165 Hs.143134 ESTs 2.8
449785 AI225235 Hε.288300 hypothetical protein FU23231 2.8
450451 AW591528 Hs.202072 ESTs 2.8 406831 N73448 Hs.50272 ESTs, Weakly similar to RS1 A.HUMAN 40S RIBOSO 2.8
411558 AA102670 Hs.70725 gamma-aminobutyric xid (GABA) A rxeptor, pi 2.8
439453 BE264974 Hs.6566 thyroid hormone receptor interxtor 13 2.8
413582 AW295647 Hε.71331 hypothetical protein MGC5350 2.8
448979 AI611378 Hs.192610 ESTε 2.8
409143 AW025980 Hs.138965 ESTs, Weakly similar to I38022 hypothetical p 2.8
410664 NM 006033 Hs.65370 lipase, endothelial 2.8
444550 BE250716 Hs.87614 ESTs 2.8
422109 S73265 Hs.1473 gastrin-releasing peptide 2.8
407788 BE514982 Hs.38991 S100 caicium-binding protein A2 2.8
445941 AI267371 Hε.172636 ESTs 2.8
459719 AW749511 Hε.301554 ESTs, Weakly similar to AF133298 1 cytochrome 2.8
413943 AW294416 Hs.144687 Homo sapiens cDNA FU12981 fis, clone NT2RP20 2.8
456456 AA477609 Hs.89563 nuclear cap binding protein subunit 1, 80kD 2.8
428301 AW628666 Hs.98440 ESTs, Weakly similar to I38022 hypothetical p 2.8
403000 BE247275 Hs.151787 U5 snRNP-spxific protein, 116 kD 2.8
413273 U75679 Hs.75257 stem-l∞p (histone) binding protein 2.8
439846 T63959 Hs.228320 hypothetical protein FLJ23537 2.8
429597 NM 003816 Hs.2442 a disiπtegrin and metaltoproteinase domain 9 2.8
412970 AB026436 Hs.177534 dual specificity phosphatase 10 2.8
455091 BE079752 gb:RC6-BT0627-140200-011-A04 BT0627 Homo sapi 2.8
410049 AW579475 gb:RCO-DT0076-110100-031-d10 DT0076 Homo sapi 2.8
452571 W31518 Hs.34665 ESTs 2.8
455666 BE065813 gb:RC2-BT0318-110100-012-a08 BT0318 Homo sapi 2.8
426343 NM.014642 Hs.169387 KIAA0036 gene product 2.8
414853 U31116 Hs.77501 εarcoglycan, beta (43kD dystrophiπ-associated 2.8
409142 AL136877 Hs.50768 SMC4 (structural maintenance of chromosomes 4 2.7
418592 X99226 Hs.284153 Fanconi anemia, complementation group A 2.7
429128 AA446869 Hs.119316 ESTs 2.7
427651 AW405731 Hs.18498 Homo sapiens cDNA FU12277 fis, clone MAMMA10 2.7
433345 AI681545 Hs.152982 hypothetical protein FU13117 2.7
403763 NM_001059*:Homo sapiens txhykinin rxeptor 3 2.7
444172 BE147740 Hs.104558 ESTs, Moderately similar to I38022 hypothetic 2.7
406753 AA505665 Hs.217493 anπexin A2 2.7
415747 AA381209 gb;EST84257 Activated T-cells 1 Homo εapienε 2.7
419875 AA853410 Hs.93557 proenkephalin 2.7
452234 AW084176 Hs.223296 ESTs, Weakly similar to 138022 hypothetical p 2.7
430466 AF052573 Hs.241517 polymerase (DNA dirxted), theta 2.7
456181 L36463 Hε.1030 ras inhibitor 2.7
416548 H62953 gb:yr47f06.r1 Soares fetal liver εplxn 1NFLS 2.7
417995 AW974175 Hs.188751 ESTs, Weakly similar to MAPB HUMAN MICROTUBUL 2.7
435347 AW014873 Hs.116963 ESTs 2.7
457339 AW971949 Hs.291252 ESTs, Weakly similar to ZN91 HUMAN ZINC FINGE 2.7
417398 N78541 Hs.177366 ESTs 2.7
408380 AF123050 Hs.44532 diubiquitin 2.7
437724 AW444828 Hε.184323 ESTs 2.7
408680 AK000093 Hs.46821 hypothetical protein FU20086 2.7
454202 AW178363 gb:RC3-HT0105-010999-002-H06 HT0105 Homo sapi 2.7
441362 BE614410 Hs.23044 RAD51 (S. cerevisix) homolog (E coli RxA ho 2.7
422278 AF072873 Hs.114218 frizzled (Drasophila) homolog 6 2.7
406092 Target Exon 2.7
447748 AI422023 Hs.161338 ESTs 2.7
443236 AI079496 Hs.134169 ESTs 2.7
433743 AF075312 Hs.236760 Homo sapiens clone HQ0262 2.7
446839 BE091926 Hε.16244 mitotic spindle coiled-coil related protein 2.7
405675 Target Exon 2.7
424625 AW904466 Hs.321197 PDZ domain protein (Drasophila inaD-like) 2.7
416250 AA581386 Hs.73452 hypothetical protein MGC10791 2.7
448592 N69546 Hs.44563 hypothetical protein 2.7
407289 AA135159 Hs.203349 Homo sapienε cDNA FU12149 fis, clone MAMMA10 2.7
407287 AI678812 gb:tu59d08.x1 NCI_CGAP_Gas4 Homo sapiens cDNA 2.7
448275 BE514434 Hs.20830 kinesiπ-like 2 2.7
412977 AA125910 Hε.191461 ESTs 2.7
431721 AB032996 Hs.268044 KIAA1170 protein 2.7
417357 AF260257 Hs.131917 retinitis pigmentosa GTPaεe regulator interx 2.7
400298 AA032279 Hs.61635 εix tranεmembrane epithelial antigen of the p 2.7
416294 D86980 Hs.79170 KIAA0227 protein 2.7
458201 AI989961 Hε.233477 ESTε, Moderately similar to A Chain A, Cyclop 2.7
425483 AF231022 Hs.158159 FAT tumor suppressor (Drasophila) homolog 2 2.7
401230 NM 014191*:Homo sapiens sodium channel, volta 2.7
422058 AA862231 Hs.334443 ESTs 2.7
452747 BE153855 Hs.61460 Ig superfamily rxeptor LNIR 2.7
430152 AB001325 Hs.234642 aquaporin 3 2.7
444006 BE395085 Hs.10086 type I transmembrane protein Fπ14 2.7
443500 AV646388 Hs.93961 Homo sapienε mRNA; cDNA DKFZp667D095 (from cl 2.7
418030 BE207573 Hs.83321 πeuromedin B 2.7
445640 AW969626 Hs.31704 ESTε, Weakly similarto KIAA0227 [H.sapienε] 2.7
418869 AW516565 gb:xq01d05.x1 Soareε.NHCeC.cervical.tumor Hom 2.7
431688 AA513906 gb:πg67c08.ε1 NCI_CGAP_Lip2 Homo sapiens cDNA 2.7
427579 AA366143 Hs.179669 hypothetical protein FU20637 2.7
423175 W27595 Hs.18653 hypothetical protein FU 14627 2.7
414737 AI160386 Hs.125087 ESTs 2.7
451813 NM.016117 Hs.27182 phospholipase A2-xtivating protein 2.7 446659 AI335361 Hs 226376 ESTs 27
419833 AA251131 Hs 220697 ESTs 27
411819 AW947884 gb PM1-MT0010-200300 001-g08 MT0010 Homo sapi 26
445592 AV654382 Hs 17947 ESTs, Weakly similar to T16534 hypothetical p 26
446102 AW168067 Hs 252956 ESTs 26
441408 AI733249 Hs 126897 ESTs 26
436027 AI864053 Hs 39972 ESTs, Weakly similar to I38588 reverse transc 26
416283 NM 005429 Hs 79141 vascular endothelial growth fxtor C 26
421470 R27496 Hs 1378 anπexin A3 26
416658 U03272 Hs 79432 fibπl n 2 (congenital contrxtural arxhnod 26
428062 AA420683 Hs 98321 hypothetical protein FU14103 26
431832 AW276866 Hs 192715 ESTs 26
426698 AA394104 Hs 97489 ESTs 26
433288 AI368873 Hs 271257 ESTs, Weakly similar to I38022 hypothetical p 26
410290 AA402307 Hs 322844 hypothetical protein DKFZp564A176 26
432865 AI753709 Hs 152484 ESTs, Weakly similar to I38022 hypothetical p 26
408690 AW864542 gb PM4-SN0016-120500-003-h02 SN0016 Homo sapi 26
440048 AA897461 Hs 328737 ESTs, Weakly similar to envelope protein (H s 26
401260 C1001031* gι|7305041|reflNP 0388761| erythro 26
435136 R27299 Hs 10172 ESTs 26
412108 AA100293 Hs 185043 ESTs 26
434442 AA737415 Hs 152826 ESTs 26
443204 AW205878 Hs 29643 Homo sapieπε cDNA FU13103 fiε, clone NT2RP30 26
419667 AU077005 Hs 92208 a disintegnn and metalloproteinase domain 15 26
422892 AA988176 Hε 121553 hypothetical protein FU20641 26
409594 AA076118 gb zm18e06 s1 Stratagene pancreas (937208) Ho 26
410008 AA079552 gb zm20h12 s1 Stratageπe pancreaε (937208) Ho 26
423038 D26528 Hε 123058 DEAD/H (Asp-Glu Ala Asp/His) box polypeptide 26
406671 AA129547 Hs 285754 met proto-oncogeπe (hepatxyte growth fxtor 26
450983 AA305384 Hs 25740 ER01 (S cerevisix) like 26
434444 AI765276 Hs 101257 hypothetical protein MGC3295 26
421817 AF146074 Hs 108660 ATP-binding cassette, sub-family C (CFTR/MRP) 26
411465 AW847663 gb IL3-CT0213-280100-056-F02 CT0213 Homo sapi 26
408625 AW243323 Hs 266785 ESTs 26
412530 AA766268 Hs 266273 hypothetical protein FU13346 26
439245 NM.013381 Hs 6510 thyrotropiπ releasing hormone degrading xtoe 26
431890 X17033 Hs 271986 integπn, alpha 2 (CD49B, alpha 2 subunit of 26
414747 U30872 Hs 77204 centromere protein F (350/400kD, mitosin) 26
401050 NM.014155* Homo sapiens HSPC063 protein (HSPC 26
405897 Target Exon 26
451153 BE092900 gb CM2-BT0742-100400-147-h04 BT0742 Homo sapi 26
407327 AA487182 Hs 269414 ESTs, Weakly similarto Z195 HUMAN ZINC FINGE 26
440159 AI637599 Hs 126127 ESTε 26
404184 NM.030903* Homo sapiens olfxtory rxeptor, f 26
428552 AW274560 Hs 129520 ESTs 26
401367 Target Exon 26
428450 NM 014791 Hs 184339 KIAA0175 gene product 26
425698 NM 016112 Hs 159241 polycystic kidney diseaεe 2 like 1 26
424783 AA913909 Hs 153088 TATA box binding protein (TBP)-aεεxιated fx 26
449432 AW451361 Hs 196529 ESTε 26
425062 H09748 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger protein) 26
452281 T93500 Hs 28792 Homo sapiens cDNA FU11041 fis, clone PLACE10 26
450705 U90304 Hs 25351 iroquois homeobox protein 5 26
421506 BE302796 Hs 105097 thymidine kinase 1, soluble 26
408391 AW859276 gb MR1-CT0352-240200-105-d02 CT0352 Homo sapi 26
427099 AB032953 Hs 173560 odd Oz ten-m homolog 2 (Drasophila, mouεe) 26
431750 AA514986 Hs 283705 ESTs 26
451807 W52854 Hs 27099 hypothetical protein FU23293 similar to ARL- 26
453331 AI240665 Hs 8895 ESTε 26
447175 AI365208 Hε 293606 ESTs 26
451878 AI821027 Hs 8429 ESTs 26
433790 BE298215 Hs 288968 RAB22A, member RAS oncogene family 26
418282 AA215535 Hs 98133 ESTs 26
434557 AW855466 Hs 271866 ESTs, Weakly similar to ALULHUMAN ALU SUBFAM 26
425704 U79293 Hs 159264 Human clone 23948 mRNA sequence 26
420894 AA744597 Hs 88854 ESTs 26
435663 AI023707 Hs 134273 ESTs 26
448037 AW195634 Hs 170401 ESTs 26
418067 AI127958 Hs 83393 cystatin E/M 26
439524 BE542950 Hε 155548 ESTs 26
402298 Target Exon 26
424081 NM.006413 Hs 139120 πbonuclease P(30kD) 26
407471 D55644 gb Human spleen PABL (pseudoautoεomal boundar 26
430994 AA490346 Hε 40530 Homo sapiens, clone MGC 17624, mRNA, complete 26
419983 W55956 Hs 94030 Homo sapiens mRNA, cDNA DKFZp586E1624 (from c 26
419699 AA248998 Hs 173044 ESTs, Weakly similar to I38022 hypothetical p 26
423637 AL137279 Hs 130187 Homo sapienε mRNA, cDNA DKFZp43401214 (from c 26
425415 M13903 Hs 157091 involucπn 26
444826 AI674482 Hs 148441 ESTε 26
413331 BE083950 gb PMO-BT0651-260200-001-b11 BT0651 Homo sapi 26
414987 AA524394 Hs 294022 hypothetical protein FU 14950 26
405041 C3001706* gι|1345652|sp|P15989|CA36 CHICK COL 26
413864 BE175582 gb RC5-HT0580-100500-022-C01 HT0580 Homo sapi 26 438746 AI885815 Hs.184727 ESTs 25
438966 AW979074 gb:EST391184 MAGE resequences, MAGP Homo sapi 2.5
433365 AF026944 Hs.293797 ESTs 2.5
412723 AA648459 Hs.335951 hypothetical protein AF301222 2.5
422656 AI870435 Hs.1569 UM homeobox protein 2 2.5
411171 AW820260 gb:QV2-ST0296-150200-040-c10 ST0296 Homo sapi 2.5
447197 R36075 gb:yh88b01.s1 Soareε plxenta Nb2HP Homo sapi 2.5
459688 U72671 Hs.151250 intercellular adhesion molxule 5, telencepha 2.5
414883 AA926960 Hs.334883 CDC28 protein kinase 1 2.5
419741 NM 007019 Hs.93002 ubiquitin carrier protein E2-C 2.5
437412 BE069288 Hs.34744 Homo sapiens mRNA; cDNA DKFZp547C136 (from cl 2.5
427366 AA885108 Hs.223806 TATA box binding protein (TBP)-assxiated fx 2.5
455549 AW994222 gb:RC3-BN0036-250200-012-e02 BN0036 Homo sapi 2.5
409676 AA077118 Hs.197298 NS1-binding protein 2.5
448305 AA625207 Hs.264915 Homo sapiens cDNA FU12908 fis, clone NT2RP20 2.5
429413 NM.014058 Hs.201877 DESC1 protein 2.5
424420 BE614743 Hs.146688 prostaglandin E synthase 2.5
427510 Z47542 Hε.179312 small nuclear RNA xtivating complex, polypep 2.5
452834 AI638627 Hs.105685 KIAA1688 protein 2.5
424354 NM 014314 Hs.145612 RNA helicase 2.5
455095 AW855598 gb:CM1-CT0278-031199-032-e08 CT0278 Homo sapi 2.5
431241 AA496799 Hs.36958 ESTs 2.5
424073 U03493 , Hs.138959 gap junction protein, alpha 7, 45kD (connexin 2.5
427239 BE270447 Hs.174070 ubiquitin carrier protein 2.5
407103 AA424881 Hs.256301 hypothetical protein MGC13170 2.5
458175 AW296024 Hs.150434 ESTs 2.5
431130 NM 006103 Hs.2719 epididymis-spxific, whey-xidic protein type 2.5
453379 AA035261 Hs.61753 ESTs 2.5
438533 AI440266 Hs.170673 ESTs, Weakly similar to T24832 hypothetical p 2.5
412313 AW936832 gb:PM2-DT0023-050400-003-h03 DT0023 Homo sapi 2.5
421733 AL119671 Hs.1420 fibroblast growth factor rxeptor 3 (achondro 2.5
443757 H05479 Hs.62314 ESTs 2.5
449300 AI656959 Hs.222165 ESTs 2.5
434913 AW872860 Hs.11056 RALBP1 protein 2.5
448946 AI652855 Hs.23363 hypothetical protein FU10983 2.5
437327 AL353942 Hs.306504 Homo sapienε mRNA; cDNA DKFZp761L23121 (from 2.5
450262 AW409872 Hs.184846 Homo sapiens, Similar to zinc finger protein 2.5
453204 R10799 Hs.191990 ESTs 2.5
420170 U43374 Hs.95631 Human πoπnal keratin∞yte mRNA 2.5
449344 AI640355 Hε.312691 ESTs 2.5
439436 BE140845 Hs.57868 ESTs 2.5
449867 AI672379 Hs.122970 hypothetical protein FU21579 2.5
452220 BE158006 Hs.212296 ESTs 2.5
433675 AW977653 Hs.75319 ribonucleotide reductase M2 polypeptide 2.5
429163 AA884766 gb:am20a10.s1 Soares_NFL_T_GBC_S1 Homo sapien 2.5
441703 AW390054 Hs.192843 leucine zipper protein FKSG14 2.5
415030 D31118 Hs.191735 hypothetical protein MGC10520 2.5
417975 AA641836 Hs.30085 hypothetical protein FU23186 2.5
451105 AI761324 gb:wi60b11.x1 NCI_CGAP_Co16 Homo sapiens cDNA 2.5
400301 X03635 Hs.1657 estrogen rxeptor 1 2.5
429386 AK001795 Hs.201179 hypothetical protein FU10933 2.5
423949 AI014546 Hs.130912 ESTs 2.5
411768 NM 013371 Hs.71979 interleukin 19 2.5
436961 AW375974 Hs.156704 ESTs 2.5
431124 AF284221 Hs.59506 doublesex and mab-3 related transcription fx 2.5
410878 AW809201 Hs.314248 ESTs, Weakly similar to ALU4 HUMAN ALU SUBFAM 2.5
418717 AI334430 Hs.86984 ESTs 2.5
443270 NM 004272 I Hs.337737 Homer, neuronal immediate early gene, 1B 2.5
448454 NM.005879 I Hs.21254 TRAF interacting protein 2.5
430072 X13294 Hs.300592 v-myb avian myeloblastosis viral oncogene hom 2.5
442966 AI394036 Hs.132237 ESTs, Weakly similar to DUS8 HUMAN DUAL SPECI 2.5
451494 AI799444 Hs.247095 ESTs, Moderately similar to ALU7.HUMAN ALU SU 2.5
418327 U70370 Hs.84136 paired-like homxdomain transcription fxtor 2.5
440381 AA917808 Hε.190495 ESTs 2.5
403983 Target Exon 2.5
451340 AW936273 gb:QV0-DT0020-090200-107-g07 DT0020 Homo sapi 2.5
447888 BE620911 Hε.126889 ESTs 2.5
441794 AW197794 Hs.253338 ESTs 2.5
424153 AA451737 Hs.141496 MAGE-like 2 2.5
453633 AA357001 Hs.34045 hypothetical protein FU20764 2.5
435647 AI653240 Hs.49823 ESTs 2.5
428780 AI478578 Hs.50636 ESTs 2.5
439108 AW163034 Hs.6467 synaptogyrin 3 2.5
422565 BE259035 Hs.118400 singed (Drosophila)-like (sea urchin fascin h 2.5
428054 AI948688 Hs.266619 ESTs 2.5
418811 AK001407 Hs.88663 hypothetical protein FU10545 2.5
409893 AW247090 Hs.57101 minichromosome maintenance deficient (S. cere 2.5
443362 AI053464 Hε.166505 ESTs 2.5
433183 AF231338 Hs.222024 transcription fxtor BMAL2 2.5
438214 H06076 Hs.26320 TRABID protein 2.5
446745 AW118189 Hs.156400 ESTs 2.5
414416 AW409985 Hs.76084 hypothetical protein MGC2721 2.5
426333 AW269088 Hs.118183 hypothetical protein FU22833 2.5 TABLE 12B
Pkey: Unique Eos probeset identifier number
CAT number: Gene cluster number Accession: Genbank xcesεion numberε
Pkey CAT number Accessions 407642 1007175 1 AW178963 AW845721 BE141041 AW806977 AW845690 AW845691 AW845724 AW176564 AW845705 AW845603 AW845729 AW845722 AW178966
AW845693 AW845585 AW845707 BE141053 BE141046 AW845570 AW845575 BE141043 BE141039 BE141070 AW062443 AW806980 AW845643
AW806969 AW845686 BE141054 BE141040 BE141044 BE141042 AW845571 AW845604 BE141047 BE141071 AW062442 AW845633 AW178968
408391 1055687.1 AW859276 AW859274 AW190959 T91463 408690 107490 1 AW864542 AA056567 AW882724 409594 114249.1 AA076118 AA975618 AA076220 409695 114876 1 AA296961 AA296889 AA076945 AA077528 AA077497 409990 116644.1 AA079337 AA079338 AW272100 410008 116812 1 AA079552 BE142525 BE142527 410049 1172307 1 AW579475 AW939654 AW939655 410784 1221005.1 AW803201 BE079700 BE062940 411098 1232093.1 AW817238 AW993985 AW993998 411171 1234393 1 AW820260 AW820332 R94406 411465 1246768 1 AW847663 AW847861 AW861080 411559 1249417.1 BE144081 BE144190AW851155 411819 1259748.1 AW947884 AW947918 AW947888 AW947883 AW947897 AW947910 AW947905 AW864751 AW947878 411958 126717 1 AA099020 AW751275 AW751276 AW751289 412279 1287332.1 BE245511 BE246133AW935247 412313 1288355.1 AW936832 AW936609 AW936657 AW936611 AW936739 AW936734 AW936779 AW936688 AW936659 AW936738 AW936827 AW936737 AW936736 AW936740 AW936833 AW936777 AW936830 AW936834 AW936829 AW936772 AW936638 AW936658 AW936636 AW936774 AW936778 AW936766 AW936776 AW936831 AW936760 AW936819
412333 1289037 1 AW937485 AW937589 AW937658 AW937654 AW937492 412367 1291505.1 AW945964 AW946020 AW946034 AW946027 AW946041 AW946044 AW946033 AW946024 AW946021 AW946029 AW846015 AW946016 AW946039
AW946045 AW946028 AW946036
412879 1334272.1 BE092219 BE092361 BE006789
413083 1348639 1 BE064528 BE064589 BE064561
413331 1361726.1 BE083950 BE084017 BE084016
413864 1395788.1 BE175582 BE175514 BE175505 BE175591 BE175530
414147 142127.-1 BE091634
414148 142133 1 BE084049 AW292907 AA135984
415317 1533847.1 Z43388 F05453 R19673 R20275 H06917
415613 1540602 1 R20233 F12901 T74740
415747 155189.1 AA381209 AA381245AA167683
416120 1571266.1 H46739 H51513 H19779
416168 1574545 1 H23687 H46460 H40239
416548 1600181.1 H62953 N76608 N72413
417742 1696282.1 R64719Z44680 R12451
418347 174149.1 AA216419 F03238AA229517
418869 179863.1 AW516565 AA229762 AA230035
419807 188252.1 R77402 AA262462 AA250988 R06794
420373 193194.1 AW968228AA259146 W01465
420637 195241.1 AW976153 AA278945 AA747691
420930 197736.1 AW888650 AW888651 BE149946 BE149948 BE149951 BE149947 AW888649 AA281840 AA281822 AW888652
422689 219896 1 AW856665 AA315006 AW954733
423733 231476.1 AA330281 AA330232 AW962521
423735 231498.1 AA330259 AA661806 AA502431 AW974633 AA649496
423841 232507.1 AW753967 AA370795 AA331630 AW962550
425005 245908.1 AI565851 AA349656 R24798
429163 300543.1 AA884766 AW974271 AA592975 AA447312
431120 328264 1 AA492588 AA492498 AA492571
431322 331543.1 AW970622 AA503009 AA502998 AA502989 AA502805 T92188
431688 336609.1 AA513906AA847734AI357044
432184 342677.1 AW971125 AA527731 N52655 AI821508 AA532420
432189 342819.1 AA527941 AI810608 AI620190 AA635266
432869 355475.1 AW974094 AA569074 AA602574
433289 36202.-1 AF005258
433584 370400.1 AW295399 AW207772 AW300641 AW070290 BE348854 AW170383 AA600968 AA778832
433644 371919.1 AW342028 AA641080 AA603282
434321 383473.1 AA629368 AW849574 AW849573
435399 405576.1 AA679463 AW813779 AW813709
437182 43421.1 AL080098 AL037472 AA432051
437938 44573.2 AI950087 N70208 R97040 N36809 AI308119 AW967677 N35320 AI251473 H59397 AW971573 R97278 W01059 AW967671 AA908598 AA251875
AI820501 AI820532 W87891 T85904 U71456T82391 BE328571 T75102 R34725 AA884922 BE328517 AI219788 AA884444 N92578 F13493 AA927794
AI560251 AW874068 AL134043 AW235363 AA663345 AW008282 AA488964 AA283144 AI890387 AI950344 AI741346 AI689062 AA282915 AW102898
AI872193 AI763273 AW173586 AW150329 AI653832 AI762688 AA988777 AA488892 AI356394 AW103813 AI539642 AA642789 AA856975 AW505512
AI961530 AW629970 BE612881 AW276997 AW513601 AW512843 AA044209 AW856538 AA180009 AA337499 AW961101 AA251669 AA251874
AI819225 AW205862 AI683338 AI858509 AW276905 AI633006 AA972584 AA908741 AW072629 AW513996 AA293273 AA969759 N75628 N22388
H84729 H60052 T92487 AI022058 AA780419 AA551005 W80701 AW613456 AI373032 AI564269 F00531 H83488 W37181 W78802 R66056 AI002839
R67840 AA300207 AW959581 T63226 F04005
438390 45662 1 AI422017 AI422945 AI363249 AI423113 AI925592 AI420795 AI208187 AI423279 AI423645 AI424090 AI359637 AL044732 D17003 438966 467436.1 AW979074AA834841 AA828650 438983 467651.1 AA828995 AA834879 AI926361 439579 47404 1 AF086400 W79232 W73990
440320 491930.1 AA879294 N67538 AI474541
444910 624951.1 AI201849 BE069007AW946544
446417 676384.1 AI299050BE256910 447197 711623 1 R36075 AI366546 R36167
448599 770766.1 AW860912AI540866
449034 794817 1 AI624049 A 117770 AI858360
450024 82296.1 AA005129AA679084AA694399
450613 840016.1 AI702055 R89204 R86260 451105 859083 1 AI761324AW880941 AW880937
451153 86054.1 BE092900AA015B77AA018521
451340 86640 1 AW936273AW340350AA017208
454202 1050507 1 AW178363AW846011 AW845964 AW845988 AW845977 AW846002
454241 1067807.1 BE144666 BE184942AW238414BE184946 454707 1230250 1 AW814989 AW814852 AW814808
454891 1239217 1 AW837349 AW837355 AW882717
454988 1248607.1 AW850140AW850195AW850192
455091 1252939 1 BE079752 BE079868 BE148989 A 855532 BE148818 BE148815 BE148796
455092 1252971.1 BE152428AW855572AW855607 455095 1252987 1 AW855598AW855608BE148763 BE148764AW855645AW855615AW855596AW855610AW855601 AW855605
455203 1259973 1 AW865450 AW865119 AW865452 AW865461 AW865325 AW865114 AW865116AW865321 AW865590 AW865390
455310 1278158 1 AW893961 AW893998AW894034AW894019
455319 1279172 1 AW895387AW895547AW895564AW895323 AW895405 AW895539 AW895538
455365 1284681 1 AW948343 AW948341 AW902855 AW984737 455549 1324696.1 AW994222 AW994377
455666 1349545 1 BE065813 BE065788 BE065889 BE065832
455750 1355998 1 BE075114 BE075283 BE075118
455838 1374605.1 BE145808 BE145807 BE181883
455987 1397735 1 BE178323 BE177978 457405 333127 T AA504860AA504911
458829 773443 1 AI557388 BE158936
459267 966605 1 AJ003631 AJ003650 AJ003651
TABLE 12C
Pkey: Unique number correεponding to an Eoε probeset
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numberε. "Dunham I. et al." refers to the publication entitled "The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489-495. Strand: Indicates DNA strand from which exons were predicted. NLposition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLposition
400612 9829646 Minus 151513-151662
400666 8118496 Plus 17982-18115,20297-20456
401050 8117628 Minus 78449-79425
401137 2547238 Minus 598-1009
401230 9929527 Minus 33835-34006,34539-34592,36461-36745,48925-49098,52604-52758
401260 8076883 Minus 86008-86355
401367 9796198 Minus 145356-145807
401458 9187886 Plus 76485-77597
401486 7341763 Plus 32585-32756,36281-36540,40791-40933,44018-44179
401575 7229804 Minuε 76253-76364
401747 9789672 Minus 118596-118816,119119-119244,119609-119761,120422-120990,130161-130381,130468-130593,131097-131258,131866- 131932,132451-132575,133580-134011
401760 9929699 Plus 83126-83250,85320-85540,94719-95287
401780 7249190 Minuε 28397-28617,28920-29045,29135-29296,29411-29567,29705-29787,30224-30573
401781 7249190 Minuε 83215-83435,83531-83656,83740-83901,84237-84393,84955-85037,86290-86814
401994 4153858 Minuε 4290443124,43211-43336,44607-44763,45199-45281,46337-46732
402048 8072512 Pluε 4393644078
402298 6598824 Plus 36758-37953
402337 6957691 Plus 41164286,16811-16973,17107-17256,19715-20040,22028-22205
402481 9797406 Plus 87891-88991
402556 9863723 Plus 13579-14026
402639 9958129 Minus 20167-22383
402800 6010175 Plus 4392144049,4618146273
402892 8086844 Minus 194384-194645
403274 8072441 Minus 104069-104179,105683-105859
403471 9930659 Minus 85867-85983
403763 7229888 Minus 4357543887
403806 8140491 Pluε 146390-146678
403983 8576059 Minus 82441-82701
404107 8098028 Minus 201699-202363
404132 6981900 Plus 11307-12434
404184 4581418 Minus 12652-13548
404253 9367202 Minus 55675-56055
404440 7528051 Plus 80430-81581
404782 9910094 Minus 15455-15589
404959 7407964 Plus 45243-45368
404981 4432779 Minus 20626-20770,22513-22721
404996 6007890 Plus • 37999-38145,38652-38998,39727-39872,4055740674,4235142450
405041 7547195 Plus 121230-121714
405196 7230083 Minus 135716-135851 405277 3980473 Plus 23471-23572
405281 6139075 Minus 34202-34351,35194-35336,4541245475,4573145958,47296-47457,4954949658497904990450231-50342,53583-53667,54111-54279
405336 6094635 Plus 33267-33563
405454 7656675 Plus 133807-134053
405545 1054740 Plus 118677-118807,119091-119296,121626-121823
405547 1054740 Plus 124361-124520 124914-125050
405657 4827303 Minus 104132-104293
405675 4557087 Plus 70304-70630
405708 4156182 Plus 55030 55604
405897 6758795 Pluε 59828-60535
405932 7767812 Minus 123525-123713
405943 6758796 Plus 20605-20812
406087 9123919 Minus 7234-7626
406092 9123919 Plus 251370-251797,252168-252882
406467 9795551 Plus 182212-182958
406554 7711566 Plus 106956-107121
406560 7711569 Minus 35162-35282
406599 8248616 Plus 10933-11086
TABLE 13A 465 GENES UP REGULATED IN CERVICAL CANCER COMPARED TO NORMAL ADULT TISSUES, LIKELY TO ENCODE EXTRACELLULAR OR CELL-SURFACE PROTEINS
Table 13A lists about 465 genes up-regulated in cervical cancer compared to normal adult tissueε that are likely to encode extrxellular or cell surfxe proteins These were selxted as for Table 12A, except that the ratio was greater than or equal to 1 7, and the β percentile value amongst cervical cancers was greater than or equal 100 units, and the predicted protein contained a stractural domain that is indicative of extrxellular localization (e g ig, fn3, egf, 7tm domains, signal sequences, transmembrane domains) The predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcesεion number
UnigenelD Unigene number
PPDomams Predicted Protein Domains
Unigene Title Unigene gene title
R1 Ratio of tumor to normal adult tisεues
Pkey ExA∞n UnigenelD PPDomams Unigene Title R1
425650 NM 001944 Hs 1925 TM,cadhenn,Cadheπn_C_term desmoglein 3 (pemphigus vulgans antigen) 436
418007 M13509 Hs 83169 SS,hemopexιn,Peptιdase_M10 matnx metalloproteinase 1 (interstitial 389
439606 W79123 Hs 58561 TM,7tm_1 G protein-coupled rxeptor 87 288
452240 AI591147 Hs 61232 TM ESTs 270
424046 AF027866 Hs 138202 SS.TM.serpin seπne (or cysteine) proteinase inhibitor 245
400289 X07820 Hs 2258 hemopexιn,Peptιdase_M10 matnx metalloproteinase 10 (stromelysin 205
418345 AJ001696 Hs 241407 SS,TM,serpιπ seπne proteinase inhibitor 13(PI13, se 201
423017 AW178761 Hs 227948 SS.serpin seπne (or cysteine) proteinase inhibitor 192
428227 AA321649 Hs 2248 SS M.IL8 small inducible cytokine subfamily B (Cys 159
447164 AF026941 Hs 17518 TM.1BR Homo sapienε cιg5 mRNA, partial sequence 138
414764 AW013887 Hs 72047 TM ESTs 129
416661 AA634543 Hs 79440 TM IGF-II mRNA-binding protein 3 127
427585 D31152 Hs 179729 SS,C1q Collagen collagen, type X, alpha 1 (Schmid metaphy 126
406467 TM.efhand Target Exon 105
428368 BE440042 Hs 83326 SS,Peptιdase_M10,hemopexιn matnx metalloproteinase 3 (stromelysin 1 102
418882 NM 004996 Hs 89433 TM,ABC_membrane,ABC_tran ATP-binding casεette, sub-family C (CFTR/ 94
419247 S65791 Hs 89764 TM.KH-domain fragile X mental retardation 1 91
446232 AI281848 Hs 194691 TM,7tm_3Rιbosomal_L13 retinoic xid induced 3 89
424905 NM 002497 Hs 153704 TM.pkinase NIMA (never in itosiε gene a) related ki 89
422420 U03398 Hs 1524 TM,tubulιn,TNF tumor nxrosis fxtor (ligand) superfamil 87
427821 AA470158 Hs 98202 TM,7tm_1 ESTs 69
436211 AK001581 Hs 334828 Ammoniumjransp hypothetical protein FU10719, KIAA1794 p 69
444342 NM.014398 Hs 10887 Lamp similar to lysosome-aεε∞iated membrane g 68
422330 D30783 Hs 115263 SS,TM,EGF epiregulin 68
447342 AI199268 Hs 19322 SSJipocalin Homo sapiens, Similar to RIKEN cDNA 20103 68
407839 AA045144 Hs 161566 TM.cadhenn.Cadheπn.C.term ESTs 66
410153 BE311926 Hs 15830 Glycos transf 2 hypothetical protein FU 12691 65
414812 X72755 Hs 77367 SS,TM,IL8 monokine induced by gamma interferon 64
421773 W69233 Hs 112457 SS ESTs 62
413385 M34455 Hs 840 TM.IDO indoteamine-pyrrole 2,3 dioxygenase 59
413753 U17760 Hs 75517 SS,lamι n_EGF,lammιn_Nterm,adh_sfιort laminin, beta 3 (nicem (125kD), kalmin 58
432239 X81334 Hs 2936 SS,Peptιdase_M10.hemopexin matnx metalloproteinase 13 (collagenase 55
418663 AK001100 Hs 41690 TM.cadheπn desmxollm 3 55
407366 AF026942 TM.IBR gb Homo sapiens cιg33 mRNA, partial seque 55
433091 Y12642 Hs 3185 SS,TM,UPAR LY6 lymph∞yte antigen 6 complex, Ixus D 54
408536 AW381532 Hs 135188 SS,TM,E1 E2_ATPase,Catιon_ATPase_C, N ESTs 54
420440 NM 002407 ' Hs 97644 SRCRUteroglobin mammaglobm 2 52
437044 AL035864 Hs 69517 TM cDNA for differentially expressed C016 ge 51
405547 SS.T ABC membrane,ABC tran.ig NM.018833* Homo sapiens transporter 2, AT 51
439223 AW238299 Hs 250618 SS UL16 binding protein 2 51
426320 W47595 Hs 169300 SS,TM,TGF-beta,TGFb propeptide transforming growth fxtor, beta 2 51
423634 AW959908 Hs 1690 TM hepaπn binding growth fxtor binding pro 50
426350 NM 003246 i Hs 2022 TM,Transglutamm_C,Transglutamιn_N,TransgluLcore transglulaminase 3 (E polypeptide, protei 50
409744 AW675258 Hs 56265 TM,metalthιo,Kelch Homo sapiens mRNA, cDNA DKFZp586P2321 (fr 49 444461 R53734 Hs.25978 TM ESTε, Weakly εimilar to 2109260A B cell g 4.8
410361 BE391804 Hs.62661 SS,TM,GBP guanylate binding protein 1, interferon-i 4.8
423673 BE003054 Hs.1695 SS,TM,Peptidase_M10,hemopexin matrix metalloproteinase 12 (mxrophage e 4.8
450375 AA009647 Hs.8850 TM,disintegrin,Pep_M12B_propep,Reprolysin a disintegnn and metalloproteinase domai 4.8
401575 NA TM Target Exon 4.6
428484 AF104032 Hs.184601 TM solute carrier family 7 (cationic amino a 4.5
425071 NM 013989 Hs.154424 SS,TM,T4 deiodiπase deiodinase, iodothyronine, type II 4.4
431808 M30703 Hs.270833 SS,TM,EGF amphiregulin (schwannoma-derived growth f 4.3
434699 AA643687 Hε.149425 TM,Nucteoside_tra2 Homo sapfens cDNA FLJ11980 fis, clone HEM 4.3
406687 M31126 Hs.272620 SS.Peptidaεe M10,hemopexin pregnancy spxific beta-1-glycoproteiπ 9 4.2
404440 TM.MAGE NM_021048:Homo sapiens melanoma antigen, 4.2
449228 AJ403107 Hs.148590 TM,PAF-AH,p450 protein related with psoriasis 4.2
444105 AW189097 Hs.166597 TM.cadherin ESTs - 4.1
409632 W74001 Hs.55279 SS.εeφin serine (or cysteine) proteinase inhibitor 4.1
423515 AA327017 Hs.162204 SS,TM,UPAR_LY6 ESTs 4.1
423738 AB002134 Hs.132195 SS,TM,trypsiπ,SEA airway trypsin-like protease 4.1
423553 AA405635 Hs.96854 TM ESTs, Weakly similar to DYLX.HUMAN CYTOPL 4.1
445537 AJ245671 Hs.12844 TM.ras EGF-like-domain, multiple 6 4.0
446989 AK001898 Hs.16740 TM hypothetical protein FLJ11036 4.0
428536 AI143139 Hs.2288 TM.efhand.Syndxan visiπiπ-like 1 3.9
413801 M62246 Hs.35406 TM ESTε, Highly εimilar to unnamed protein p 3.9
429441 AJ224172 Hs.204096 Uteroglobin lipophilin B (uteroglobin family member), 3.9
409601 AF237621 Hε.80828 TM,filamentfilament,C2 keratin 1 (epidermolytic hyperkeratosis) 3.8
439238 N47305 Hs.46668 TM ESTs 3.8
446292 AF081497 Hs.279682 Ammonium.transp Rh type C glycoprotein 3.8
405545 SS,TM,proteasome,ig,ABC_memb,tranABC_tran, (MDR/TAP) (TAP2) 3.8
422938 NM 001809 Hs.1594 TM.thiolase centromere protein A (17kD) 3.7
423217 NM.000094 Hs.1640 SS,TM,th3,vwa,Collagen,Kunitz_BPTI collagen, type VII, alpha 1 (epidermolysi 3.7
430686 NM 001942 Hs.2633 SS,TM,cadherin,Cadherin_C_term desmoglein 1 3.7
444707 AI188613 Hs.41690 TM.cadherin desmxollin 3 3.7
409582 R27430 Hs.271565 TM ESTs 3.6
408771 AW732573 Hs.47584 TM,K_tetra,ion_trans potassium voltage-gated channel, delayed- 3.6
400441 M15530 Hs.99879 TM,G-alpha B-cell growth fxtor 1 (12kD) 3.6
413278 BE563085 Hs.833 TM,ubiquitinlaminin_G,laminin_EGF,kazal interferon-stimulated protein, 15 kDa 3.6
426514 BE616633 Hs.170195 SS,TGFb_propeptide,TGF-beta bone morphogeπetic protein 7 (osteogenic 3.6
424927 AW973666 Hs.153850 SS hypothetical protein C321D2.4 3.6
408591 AF015224 Hs.46452 SS.TM.Uteroglobin mammaglobin 1 3.5
407756 AA116021 Hs.38260 SS,UCH-1,UCH-2 ubiquitin εpxific protease 18 3.5
407137 T97307 TM.GDA1.CD39 gb:ye53h05.s1 Soares fetal liver spleen 1 3.5
411274 NM 002776 Hs.69423 trypsin kallikrein 10 3.5
400666 SS,hemopexin,Peptidase_M10 NM_002425:Homo εapienε matrix etalloprot 3.5
412471 M63193 Hs.73946 SS.TM.GIycos transf 3,Cam xyltransf endothelial cell growth fxtor 1 (platele 3.4
450650 T65617 Hs.101257 TM hypothetical protein MGC3295 3.4
451778 AI826131 Hs.71243 ig ESTs, Weakly similar to zinc finger prate 3.4
430397 AI924533 Hs.105607 SS.TM bicarbonate transporter related protein 1 3.4
449722 BE280074 Hs.23960 TM.cyclin cyclin B1 3.4
422487 AJ010901 Hs.198267 TM.vwd mucin 4, trxheobranchial 3.4
449101 AA205847 Hs.23016 SS,TM,7tm_1 G protein-coupled rxeptor 3.3
418994 AA296520 Hs.89546 SS MJxtin c.suεhi.EGF selxtiπ E (endothelial adheεion molxule 3.3
421379 Y15221 Hs.103982 SS.TM.IL8 small inducible cytokine subfamily B (Cys 3.3
414774 X02419 Hs.77274 SS.kringle.trypεin plasminogen xtivator, urakinase 3.3
431958 X63629 Hs.2877 SS,TM,Cadherin_C_term,cadherin cadherin 3, type 1, P-cadherin (plxental 3.3
418462 BE001596 Hs.85266 SS,TM,integrin_B,fn3 integnn, beta 4 3.3
424687 J05070 Hs.151738 SS,Peptidaεe_M10,fn2,hemopexin matrix metalloproteinase 9 (gelatinase B, 3.3
401486 NA SS.TM.trypsin C4000647*:gi|4758508|ref|NP_004253.1| air - 3.2
408113 T82427 Hs.194101 TM,7tm 3Ribosomal L13 Homo sapiens cDNA: FU20869 fis, clone AD 3.2
427359 AW020782 Hs.79881 TM,7tm 1 Homo sapiens cDNA: FU23006 fis, clone LN 3.2
452934 AA581322 Hs.4213 SS,TM,ig hypothetical protein MGC16207 3.1
448988 Y09763 Hs.22785 SS.TM gamma-aminobutyric xid (GABA) A rxeptor 3.1
439750 AL359053 Hs.57664 TM,integrin_B,Ricin_B Ixtinrrm Homo sapiens mRNA full length insert cDNA 3.1
414696 AF002020 Hε.76918 SS,TM,Patched Niemann-Pick disease, type C1 3.1
435604 AA625279 Hs.26892 TM uncharxterized bone marrow protein BM040 3.1
453883 A1638516 Hs.22630 TM,Ets,SAM_PNT cofxtor required for Sp1 transcriptional 3.0
448733 NM 005629 Hs.187958 SS,TM,SNF,ABC_tran,isodh,pkinase,DSPc,Ribosomal. solute carrier family 6 (neurotransmitter 3.0
444946 AW139205 Hs.156457 SS.TM.abhydrolase hypothetical protein FU22408 3.0
437938 AI950087 TM,histone,ig,MHC_l gb:wq05c02.x1 NCI_CGAP_Kid12 Homo sapiens 3.0
424441 X14850 Hs.147097 TM.histone H2A histone family, member X 3.0
427061 AB032971 Hs.173392 TM KIAA1145 protein 3.0
409703 NM.006187 Hs.56009 SS 2'-5'-oligoadenylate εynthetase 3 (100 kD 3.0
447313 U92981 Hs.18081 TGF-beta Homo sapiens clone DT1 P1 B6 mRNA, CAG rape 3.0
431070 AW408164 Hs.249184 ABC tran transcription fxtor 19 (SC1) 2.9
446269 AW263155 Hε.14559 TM hypothetical protein FU 10540 2.9
421190 U95031 Hs.102482 TM.vwd mucin 5, subtype B, trxheobranchial 2.9
452732 BE300078 Hs.80449 TM Homo sapienε, clone 1MAGE3535294, mRNA, 2.9
443859 NM.013409 Hs.9914 SS.kazal folliεtatin 2.9
446733 AA863360 Hs.26040 TM,p450 ESTs, Weakly similar to fatty xid omega- 2.9
449746 A1668594 Hs.176588 SS,p450 ESTs, Weakly similar to CP4Y.HUMAN CYTOCH 2.9
418844 M62982 Hs.1200 SS,TM,lipoxygeπase,PLAT arxhidonate 12-lipoxygenase • 2.9
414581 AA256213 Hs.72010 TM,Cam_xyltransf,Choline kinase,SC01-SenC ESTs 2.9
431629 AU077025 Hs.265827 SS,tRNA_antiSH2,SH3,pkinase interferon, alpha-inducible protein (cion 2.8
445873 AA250970 Hs.251946 SS,rrm,PABPpkinase,14-3-3,rrm poly(A)-binding protein, cytoplasmic 1-li 2.8
438113 AI467908 Hs.8882 TM,7tm_1 ESTs 2.8
410310 J02931 Hs.62192 SS,TM,Tisεue_fx coagulation fxtor III (thromboplastin, t - 2.8 411558 AA102670 Hε.70725 SS.TM gamma-aminobutyric xid (GABA) A rxeptor 2.8
413273 U75679 Hε.75257 TM.ig.pkinase stem-l∞p (histone) binding protein 2.8
426343 NM 014642 Hs.169387 TM,SCAN7tm 1 KIAA0036 gene product 2.8
433345 AI681545 Hs.152982 SS hypothetical protein FU13117 2.7
452234 AW084176 Hs.223296 TM ESTs, Weakly similar to I38022 hypothetic 2.7
456181 L36463 Hs.1030 TM,RA,VPS9 ras inhibitor 2.7
408380 AF123050 Hs.44532 TM,ubiquitin7tm 3,ANF_rxeptor,sushi diubiquitin 2.7
422278 AF072873 Hs.114218 TM,Frizzfed,Fz frizzled (Drasophila) homolog 6 2.7
446839 BE091926 Hs.16244 TM mitotic spindle coiled-coil related prote 2.7
416250 AA581386 Hs.73452 TM,REJ,PLAT,PKD,WSC,LRRCT,GPSPMP22_Claudin hypothetical protein MGC10791 2.7
407287 A1678812 TM.rascadherin gb:tu59d08.x1 NCI_CGAP_Gas4 Homo sapiens 2.7
412977 AA125910 Hs.191461 TGF-beta ESTs 2.7
400298 AA032279 Hs.61635 TM six transmembrane epithelial antigen of t 2.7
425483 AF231022 Hs.158159 EGF.cadherin.la iπin.G FAT tumor suppressor (Drasophila) homolog 2.7
430152 AB001325 Hε.234642 SS,TM,MIP aquaporin 3 2.7
444006 BE395085 Hs.10086 SS.TM type I transmembrane protein Fn14 2.7
418869 AW516565 TM,RasGAP,IQ,WW gb:xq01d05.x1 Soares.NHCeC.cervicaLtumor 2.7
416658 U03272 Hs.79432 SS,TM,EGF,TB fibrillin 2 (congenital conlractural arac 2.6
410290 AA402307 Hs.322844 SS,TM,Sema,TIG,Plexin_repeat hypothetical protein DKFZp564A176 2.6
419667 AU077005 Hs.92208 SS,TM,disintegrin,Reprolysin,Pep_M12B_propep a disintegnn and metalloproteinase domai 2.6
406671 AA129547 Hs.285754 TM.pkinase.Plexiπ repeat,Sema,TIG,LIM met proto-oncogeπe (hepatocyte growth fac 2.6
434444 AI765276 Hs.101257 TM hypothetical protein MGC3295 2.6
421817 AF146074 Hs.108660 TM,ABC_tran,ABC_membrane,Rhomboid ATP-binding cassette, sub-family C (CFTR/ 2.6
431890 X17033 Hs.271986 vwa,FG-GAP,integrin„A integnn, alpha 2 (CD49B, alpha 2 subunit 2.6
452281 T93500 Hs.28792 TGF-beta,TGFb_propeptide Homo sapiens cDNA FLJ 11041 fis, clone PLA 2.6
421506 BE302796 Hs.105097 TM.TK thymidine kinase 1, soluble 2.6
453331 AI240665 Hs.8895 TM.diεintegrin.Pep M12B_propep,Reprolyεin ESTs 2.6
447197 R36075 TM.SDF gb:yh88b01.s1 Soares plxenta Nb2HP Homo 2.5
459688 U72671 Hs.151250 SS.TM.ig intercellular adhesion motecule 5, telenc 2.5
437412 BE069288 Hs.34744 TM,ABC_tran,ABC_membraπe,Rhomboid Homo sapfens mRNA; cDNA DKFZp547C136 (fro 2.5
429413 NM 014058 Hs.201877 trypsin DESC1 protein 2.5
424420 BE614743 Hs.146688 TM.MAPEG prostaglandin Eεynthase 2.5
427239 BE270447 Hs.174070 TM,UQ_con ubiquitin earner protein 2.5
407103 AA424881 Hs.256301 TM.cNMP.bindingtrypsin hypothetical protein MGC13170 2.5
431130 NM 006103 Hs.2719 SS.TM.wap epididymis-spxific, whey-xidic protein 2.5
453379 AA035261 Hs.61753 PAN.kringle.trypsin ESTs 2.5
421733 AL119671 Hs.1420 SS,TM,ig,pkinase fibroblast growth factor rxeptor 3 (xho 2.5
452220 BE158006 Hs.212296 TM,integrin_A,FG-GAP ESTs 2.5
417975 AA641836 Hs.30085 SS.trypsiπ hypothetical protein FU23186 2.5
440381 AA917808 Hs.190495 TM ESTs 2.5
441794 AW197794 Hs.253338 TM ESTs 2.5
439108 AW163034 Hs.6467 SS.TM synaptogyrin 3 2.5
401103 NA TM.vwd C12001233.-gi|7305361|ref|NP_038652.1| oto 2.4
430630 AW269920 Hs.2621 TM.cystatin cyεtatin A (stefin A) 2.4
430129 BE301708 Hs.233955 TM,Glyco_transf_11 hypothetical protein FU20401 2.4
415621 AI648602 Hs.55468 TM,histone,Sx1sugar_tr ESTs 2.4
402745 SS,TM,EGF,ldl rxepLWhyroglobulin 1 NM_002508:Homo sapiens nidogen (enactin) 2.4
407758 D50915 Hs.38365 SS.TM KIAA0125 gene product 2.4
457570 AA579426 TM gb:nf37c09.s1 NCI_CGAP_Pr2 Homo sapiens c 2.4
429574 BE268321 Hε.208912 SS M hypothetical protein MGC861 2.4
431211 M86849 Hs.323733 SS.TM.connexin gap junction protein, beta 2, 26kD (conne 2.4
452865 AI924046 Hs.119567 SS,TM,PMP22_Claudin ESTs, Weakly similar to A47582 B-cell gro 2.4
420511 AF052692 Hs.98485 SS.TM.connexin gap junction protein, beta 3, 31kD (conne 2.4
437897 AA770561 Hs.146170 SS.pro isomerase hypothetical protein FU22969 2.4
437846 AA773866 Hs.244569 TM esophagus cancer-related gene-2 "" 2.4
418432 M14156 Hs.85112 Insulin insulin-like growth fxtor 1 (somatomedin 2.3
438108 AI471795 Hs.287776 TM vanilloid receptor-related osmotically ac 2.3
453406 AI192987 Hs.61784 pkiπase,Furin-like,R∞ep_L_domain hypothetical protein FU14451 2.3
435542 AA687376 Hs.269533 pkinase,RhoGEF,ig,PH,SH3 ESTs ' 2.3
434517 AA635690 Hs.337251 TM hypothetical protein MGC2487 2.3
431630 NM 00220' 1 Hs.265829 SS.TM.FG-GAP.integrin.A integnn, alpha 3 (antigen CD49C, alpha 3 2.3
422310 AA316622 Hs.98370 SS,TM,fn3,ig,pkiπase,Ribosomal_L36e,p450 cytochrome P450, subfamily IIS, polypepti 2.3
441954 AI744935 Hs.8047 TM,Band_7,AAA,cdc48_N Fanconi anemia, complementation group G 2.3
416091 AF295370 Hs.283082 SS.T .Defensin.beta defensin, beta 3 2.3
429359 W00482 Hs.2399 SS,TM,Peρtidase_M10,hemopexin matrix metalloproteinase 14 (membrane-ins 2.3
409402 AF208234 Hs.695 TM.cystatin cystatin B (stefin B) 2.3
432284 AA532807 Hs.105822 TM.pkinase ESTs 2.3
408243 Y00787 Hs.624 SS,TM,IL8 interleukin 8 2.3
423229 AC003965 Hs.125532 SS.trypεin protease, serine, 26 2.3
408713 NM 001248 Hs.47042 GDA1.CD39 xtonucteoside triphosphate diphosphohydr 2.3
440502 AI824113 Hs.78281 RGS.GoLoco.RBD regulator of G-protein signalling 12 2.3
429929 AB014583 Hs.226275 TM KIAA0683 gene product 2.3
439963 AW247529 Hs.6793 TM,p450Etε platelet-activating fxtor xetylhydrolas 2.3
428953 AA306610 Hs.194676 SS MJNFR c6,arf,Stathmin,DEAD tumor necrosis fxtor rxeptor superfamil 2.3
439398 AA284267 Hs.221504 SS ESTs 2.2
440371 BE268550 Hs.80449 TM Homo sapiens, clone IMAG&3535294, mRNA, 2.2
452203 X57522 Hs.158164 SS,TM,ABC_tran,ABC membrane transporter 1 , ATP-binding cassette, sub- 2.2
407811 AW190902 Hs.40098 SS cysteine knot superfamily 1 , BMP antagoni 2.2
432078 BE314877 Hs.24553 TM hypothetical protein FU 12541 similar to 2.2
429113 D28235 Hs.196384 SS,TM,EGF prostaglandin-endoperoxide synthase 2 (pr 2.2
452755 AW138937 Hs.213436 Glyco.iransf.29 ESTs, Weakly similar to A34087 hypothetic 2.2
428434 AW363590 Hs.65551 SS Homo sapienε, Similar to DNA εegment, Chr 2.2
429922 Z97630 Hs.226117 TM,linker_histone7tm_1 H1 histone family, member 0 ' 2.2 417903 NM 002342 Hs 1116 SS,TM,ASC,TNFR_c6 lymphotoxin beta rxeptor (TNFR superfami 2 2
422012 AW403423 Hε 110746 SS.homeobox pou HCR (a-helrx coiled-coil rod homologue) 22
433090 AI720050 Hε 145362 SS.TM immortalization upregulated protein 22
417576 AA339449 Hs 82285 TM,AIRS,formyl transf.GARS phosphoπbosylglyc amide formyltransfera 22
409994 D86864 Hs 57735 IP transSH2,SH3 xetyl LDL receptor, SREC 22
417433 BE270266 Hs 82128 SS,TM,LRRCT,LRRNT,LRR 5T4 oπcofetal trophoblaεt glycoprotein 22
416763 AI908127 Hs 79748 TM,alpha-amylase7tm_1 solute earner family 3 [activators of di 22
425999 AW513051 Hs 332981 TM.FAD binding 2.P53PA Ribosomal S2.FAD bindi ESTs, Weakly similar to I38022 hypothetic 22
452799 AI948829 Hε 213786 TM ESTs 22
414733 BE514535 Hε 77171 TM.MCMHeme.oxygenase minichromosome maintenance deficient (S 22
448153 Y10805 Hs 20521 SS,TM,Na Ca Ex HMT1 (hnRNP methyltransferase, S cerevis 22
428969 AF120274 Hs 194689 SS artemin 22
443171 BE281128 Hs 9030 SS,TM,7tm 1,rrm TONDU 22
408308 AL033377 Hs 44197 TM,7tm 2 hypothetical protein DKFZp564D0462 22
409533 AW969543 Hs 21291 TM mitogen xtivated pratem kinase kinase k 22
408201 AK000568 Hs 43654 TM hypothetical protein FU20561 2 1
408996 AI979168 Hs 82226 TM glycoprotein (tranεmembraπe) nmb 2 1
417900 BE250127 Hs 82906 TM,WD40,pro isomerase CDC20 (cell division cycle 20, S cerevis 2 1
437191 NM 006846 Hs 331555 SS,TM,kazal seπne protease inhibitor, Kazal type, 5 2 1
412834 R77123 Hs 79881 TM,7tm_1 Homo sapiens cDNA FLJ23006 fis, clone LN 2 1
431117 AF003522 Hs 250500 SSJM.DSLEGF delta (Drasophila) like 1 2 1
447674 BE270640 Hs 19192 TM,pkιnaseras,arf cyclm-dependent kinase 2 2 1
409651 H96643 Hs 283565 bZIPcofilιn_ADF,EGF FOS-like antιgen-1 2 1
440495 AA887212 Hs 14161 TM,NSFNa Ca_Ex hypothetical protein DKFZp434H930 2 1
429415 NM.002593 Hs 202097 SS,CUB,NTR,MAM,TIL,TILa,vwd,EPO TPO procollageπ C-endopeptidase enhancer 2 1
421013 M62397 Hs 1345 TM mutated in colorxtal cancers 2 1
447827 U73727 Hs 19718 SS,TM,Y_phoεphataεefn3 ig MAM protein tyrosine phosphataεe, rxeptor ty 2 1
449224 AW995911 Hs 299883 fn3 hypothetical protein FU23399 2 1
452679 Z42387 Hs 83883 TM transmembrane, prostate androgen induced 2 1
409956 AW103364 Hs 727 SS.TGF betaTGFb.propeptide inhibin, beta A (xtiv A, xtivm AB al 1
438580 AA811262 Hs 299202 TM.pkinaεeεugar.fr ESTs 2 1
406400 SS.TM.trypsin NM.007196 Homo sapiens kallikrein 8 (neur 2 1
424965 AW956282 Hs 144609 TM Homo sapiens, Similar to RIKEN cDNA 57305 2 1
412270 AC005262 Hs 73797 TM,G-alpha guanine nucleotide binding protein (G pro 2 1
428471 X57348 Hs 184510 TM.14-3-3 stratifin 2 1
427375 AL035460 Hs 177536 SS.Zπ carbOpept,hormone5Reprolysιn metaltocarboxypepttdase CPX-1 2 1
416498 U33632 Hs 79351 TM potasεium channel, subfamily K, member 1 2 1
423453 AW450737 Hs 128791 SS,Granιn,CDP OH.P.transf CGI-09 protein 2 1
417944 AU077196 Hs 82985 SS,COLFI,Collagen,vwc collagen, type V, alpha 2 2 1
424197 AF096834 Hs 142989 SS,TM,CSD germ cell spxific Y-box binding protein 2 1
446163 AA026880 Hs 25252 TM,fn3 prolxtin rxeptor 2 1
417331 AW411297 Hs 81972 TM,SH2,PID SHC (Src homology 2 domain-containing) tr 2 1
430413 AW842182 Hs 241392 IL8.PX small inducible cytokine A5 (RANTES) 2 1
421685 AF189723 Hs 106778 TM,E1-E2_ATPaεe,HydrolaseE1-E2_ATPase ATPase, Ca transporting, type 2C, member 2 1
407305 AA715284 TM pkmase.Sema.Plexin repeat.TIG.LIM gb nv35f03 r1 NCI.CGAP.Br5 Homo sapiens c 2 1
407792 AI077715 Hs 39384 SS putative sxreted ligand homologouε to fj 20
418695 AA447014 Hs 193261 SS hypothetical protein MGC2991 20
439738 BE246502 Hs 9598 TM,RasGAP,IQ,WW εema domain, immunoglobulin domain (Ig), 20
433398 AW843150 Hε 112412 TM,PMP22_Claudιn ESTs 20
456327 H68741 Hs 38774 TM,Glyco transf.8 ESTs 20
446872 X97058 Hs 16362 TM pynmidinergic receptor P2Y, G-pratein co 20
419726 U50330 Hs 1274 SS,TM,Astxιn,CUB,EGF bone morphogenetic protein 1 20
410116 AW630671 Hs 58636 SS M squamouε cell carcinoma antigen rxognize 20
426500 NM 01463E I Hs 170156 TM KIAA0450 gene product 20
452194 AI694413 Hs 332649 TM,7tm 3,ANF_receptor,sushι olfxtory rxeptor, family 2, subfamily I " 20
418140 BE613836 Hs 83551 TM,E1-E2_ATPase micrafibnllar-assxiated protein 2 20
425855 AF135025 Hs 159679 SS.trypsiπ kallikrein 12 20
434346 AA630445 Hs 116773 TM.Fe c reduct ESTs 20
426274 D38122 Hs 2007 TM.TNF tumor nxrosis fxtor (ligand) superfamil 20
440008 AW051683 Hs 277686 TM,RhoGEF,FYVE,PH ESTs 20
424634 NM 003613 Hs 151407 ig.tsp cartilage intermediate layer protein, nuc 20
446641 AL049229 Hs 15787 TM pk ase.rrm Homo sapiens mRNA, cDNA DKFZp564O1016 (fr 20
418851 AI417828 Hs 192435 TM ESTs 20
440351 AF030933 Hs 7179 TM,Rad1,Cadheπn C term RAD1 (S pombe) homolog 20
439496 BE616501 Hs 32343 SS Homo sapiens, Similarto RIKEN cDNA 11100 20
454197 BE140966 TM.Ammonium transpkinesin.Ammonium transp gb MR0-HT0065-081199-002-b06 HT0065 Homo 20
433573 AF234887 Hs 57652 TM,7tm_2,GPStRNA synL2b,Seryl_tRNA_N cadhenn, EGF LAG seven-pass G-type r ep 20
429211 AF052693 Hs 198249 TM.connexin gap junction protein, beta 5 (connexin 31 20
420737 L08096 Hs 99899 SS.TM.TNF tumor nxrosis fxtor (ligand) superfamil 20
455333 AW897851 TM.GIyco hydro 2 gb RC1-NN0063-100500-022-C08 NN0063 Homo 20
414784 NM 000344 Hs 288986 SS,TM,BIR survival of motor neuron 1 , telomeπc 20
435836 AW292532 Hs 250175 TM.GNS1 SUR4 homolog of yeast long chain polyuπsaturat 20
411789 AF245505 Hs 72157 TM,ιg,LRRCT DKFZP564I1922 protein 20
441455 AJ271671 Hs 7854 TM,ras,DENN zinc/iron regulated transporter-like 20
426068 AF029778 Hs 166154 SS,TM,DSL,EGF,NUDIX jagged 2 20
439733 AL365412 Hs 107203 TM,Sm hypothetical protein from EUROIMAGE 17593 20
435014 BE560898 Hs 10026 TM.Ribosomal L17 mit∞hondπal πbosomal protein L17 1 9
457819 AA057484 Hs 35406 TM ESTs, Highly similar to unnamed protein p 1 9
422737 M26939 Hs 119571 SS,Collageπ,COLFI collagen, type III, alpha 1 (Ehlers-Danlo 1 9
431104 AW970859 Hs 313503 Sema,ιg ESTs 1 9
432210 AI567421 Hs 273330 TM,lamιπιn_G,lamιnιn_EGF,kazalubιquιtιn Homo sapiens, clone IMAGE 3544662, mRNA, 1 9
436511 AA721252 Hs 291502 TM,dιsιntegπn,Reprolysιn,Pep M12B_propep pkmase, ESTs 1 9
419216 AU076718 Hs 164021 SS.IL8 small inducible cytokine subfamily B (Cyε 1 9 432169 Y00971 Hs.2910 TM.Pribosyltran phosphoribosyl pyrophosphate synthetase 2 1.9
441128 AA570256 Hs.54628 TM.ras ESTs, Weakly similar to T23273 hypothetic 1.9
447160 AA330310 Hs.24181 TM ESTs 1.9
419138 U48508 Hs.89631 TM,RYDR_ITPR,RyR,SPRY ryanodine rxeptor 1 (skeletal) 1.9
457817 AA247751 Hs.79572 TM,hemopexin,Peptidase_M10 cathepsin D (lysosomal aspartyl proteaεe) 1.9
431009 BE149762 Hε.48956 SS.TM.connexin gap junction protein, beta 6 (connexin 30 1.9
428957 NM.003881 Hs.194679 SS,TM,vwc,lGFBP,tsp_1 WNT1 inducible signaling pathway protein 1.9
418546 AA224827 TM,vwa,FG-GAP,integriπ_A gb:nc32g04.s1 NCI_CGAP_Pr2 Homo εapiens c 1.9
400749 SS,TM,ldl_rxept_a,fn3,ldLrxepLb NM.003105*:Homo εapienε sortilin-related 1.9
408369 R38438 Hs.182575 F-protein solute carrierfamily 15 (H??? transporte 1.9
422765 AW409701 Hs.1578 TM.BIR bxuloviral IAP repeat-containing 5 (surv 1.9
417409 BE272506 Hs.82109 TM.Syndxan syndxan 1 1.9
407720 AB037776 Hs.38002 TM.calponin.CH KIAA1355 protein - 1.9
418830 BE513731 Hs.88959 TM.CDP-OH P transf.MCM hypothetical protein MGC4816 1.9
434769 AA648884 Hs.134278 TM.CDP-OH P transfMCM Homosapiens cDNA FU12676 fis, clone NT2 1.9
421593 NM.017436 Hs.105956 SS M globotriaosylceramide/CD77 synthase; Gb3/ 1.9
426064 BE387014 Hs.166146 TM.WH1 Homer, neuronal immediate eady gene, 3 1.9
404604 NA TM Target Exon 1.9
422753 AI928995 Hs.1575 SS,TM,Sm small nuclear ribonucleoprotein D3 polype 1.9
422739 H20106 Hs.119591 SS.CIaLadaptor.ε adaptor-related protein complex 2, sigma 1.9
433068 NM 006456 Hs.288215 SS.Pribosyltran sialyltransferase 1.9
419594 AA013051 Hs.91417 TM topoisomerase (DNA) II binding protein 1.9
428188 M98447 Hs.22 TM.Transglutamin C,Transglutamin_N,Transglut_∞re transglutaminase 1 (K polypeptide epiderm 1.9
428343 AL043021 Hs.12705 TM,Rhomboid,HMG_boxTPR ESTs 1.9
429592 AB029041 Hs.209646 Troponin KIAA1118 protein 1.9
431620 AA126109 Hs.264981 C2,PH,RasGAP,NTP_transf_2 2'-5'-oligoadenylate synthetase 2 (69-71 1.9
424670 W61215 Hs.116651 ig epithelial V-like antigen 1 1.9
428373 A1751656 Hε.183986 SS,TM,ig poliovirus receptor-related 2 (herpesviru 1.9
453449 W16752 Hs.32981 SS.ig.Sema sema domain, immunoglobulin domain (Ig), 1.9
432304 AA932186 Hs.69297 TM,7tm_1 ESTs 1.9
432673 AB028859 Hs.278605 TM.DnaJ.DπaJ CDnaJ DnaJ (Hεp40) homolog, subfamily B, member 1.9
416207 NM.014745 Hs.336433 SS,TM,zf-DHHC Homo sapiens, clone MGG2908, mRNA, compl 1.9
408988 AL119844 Hs.49476 TM,Plexin_repeat,Sema,tsp_1 Homo sapienε clone TUA8 Cri-du-chat regio 1.9
417426 NM.002291 Hs.82124 SS,laminin_EGF,laminin_Nterm laminin, beta 1 1.9
443883 AA114212 Hs.9930 SS,TM,serpin,Marek_A εerine (or cysteine) proteinase inhibitor 1.9
433328 AW298159 Hs.23644 SSJM ESTs, Weakly similar to S65824 reverse tr 1.9
419981 AA897581 Hs.128773 TM.Ski Sno ESTs 1.8
420931 AF044197 Hε.100431 SS,TM,IL8 small inducible cytokine B subfamily (Cys 1.8
415023 AA932146 Hs.133494 TM,Ribθ8omaI_S17Ribosomal_L13 Homo sapiens clone TCCCIA00164 mRNA seque 1.8
413644 BE154910 Hs.278793 TM,Glyco_hydro_2 ESTs, Weakly similar to Z195 HUMAN ZINC F 1.8
449987 AW079749 Hε.184719 TM,ABC_tran,ABC_membraneion_trans ESTs, Weakly similar to ALULHUMAN ALU SU 1.8
421340 F07783 Hε.1369 SS.sushi dxay xcelerating fxtor for complement 1.8
417866 AW067903 Hε.82772 SS,TM,Collagen,COLFI,TSPN collagen, type XI, alpha 1 1.8
430259 BE550182 Hs.127826 TM,transmembrane4RasGEF,RA RalGEF-like protein 3, mouse homolog 1.8
432998 AA835948 Hs.153307 TM.SDF ESTs 1.8
431671 NM.016937 Hs.267289 TM.NA polymerase (DNA dirxted), alpha 1.8
411773 NM.006799 Hs.72026 trypsin protease, serine, 21 (testiεin) 1.8
425247 NM.005940 Hs.155324 SS,TM,Peptidase_M10.hemopexin matrix metalloproteinase 11 (stromelysin 1.8
422976 AU076657 Hs.1600 TM,cpn60_TCP1,Sema chaperonin containing TCP1, subunit 5 (ep 1.8
425159 NM 004341 Hs.154868 SS,TM,GATase,OTCxe,CPSase_L_chain,Dihydrooro carbamoyl-phosphate synthetase 2, asparta 1.8
447776 AI525625 Hs.130181 Ricin_B_lxtiπ UDP-N-xetyl-alpha-D-galxtosamine:polype 1.8
426908 AW815163 Hs.172851 SS,TM,fusionjly,Myosin_tailadh_short arginase, type II 1.8
408116 AA251393 Hs.289052 TM,Na_Ca_ExCarn_xyltraπsf Homo sapiens, Similar to RIKEN cDNA 54304 1.8
417847 AI521558 Hs.7331 Uteroglobin hypothetical protein FLJ22316 1.8
415791 H09366 Hs.78853 SS,TM,UNG uracil-DNAglycosylase "' 1.8
407903 AI287341 Hs.154029 TM,ubiquitin,laminin_G,laminin_EGF,kazal bHLH fxtor Hes4 1.8
422511 AU076442 Hs.117938 TM,p450 collagen, type XVII, alpha 1 1.8
414117 W88559 Hs.1787 TM,ion_traπs,K_tetra prateolipid protein 1 (Pelizaeus-Merzbxh 1.8
426841 AI052358 Hs.193726 TM.aεp ESTs 1.8
415272 AA164215 Hs.203186 TM,TPR,pkinaεe,ig,B56 ESTs 1.8
426440 BE382756 Hs.169902 TM.sugar tr.Fork head solute carrier family 2 (fxilitated glue 1.8
419488 AA316241 Hs.90691 FGF nucleophosmin/nucleoplasmin 3 1.8
418452 BE379749 Hs.85201 SS,TM,lxtin c C-type (calcium dependent, carbohydrate-r 1.8
431363 M86528 Hs.266902 SS.NGF neurotrophin 5 (neuratrophin 4/5) 1.8
440975 AW499914 Hε.7579 SSJM hypothetical protein FU 10402 1.8
438962 BE046594 TGF-beta,bZIP gb:hn41c11.x1 NCI CGAP RDF2 Homo sapienε 1.8
414602 AW630088 Hε.76550 SS Homo εapiens mRNA; cDNA DKFZp564B1264 (fr 1.8
418054 NM.002318 Hs.83354 TM,mito_carr,Lysyl_oxidxe lysyl oxidase-like 2 1.8
440501 AA887391 Hs.202229 TM.GalxtosyLT ESTs 1.8
449309 AW589823 Hs.224189 TM ESTs 1.8
421461 AW291023 Hε.97255 TM,LysyLoxidase,SCP2,Band_7 ESTs, Weakly similar to A46010 X-linked r 1.8
412584 X54870 Hs.74085 TMJectin.c DNA segment on chromosome 12 (unique) 248 1.8
441565 AW953575 Hs.303125 TM p53-induced protein PIGPC1 1-8
431837 T79326 Hs.326553 TM,7tm_3,ANF_receptor,sushi olfxtory rxeptor, family 2, subfamily I 1.8
436251 BE515065 Hs.296585 SS,Y_phosphataseTIG nucleolar protein (KKE/D repeat) 1.8
448633 AA311426 Hs.21635 TM,EGF,lamiπin_G,fibrinogen_C,F5_F8_type_C,tubulin tubulin, gamma 1 1.8
424291 AL120051 Hs.144700 TM,Ephrin,Hist_dexetyl ephrin-B1 1.8
415388 AF018081 Hs.78409 SS,TM,TSPN,Collagen collagen, type XVIII, alpha 1 • 1.8
435550 AI224456 Hs.4934 TM.LRR.LRRCT H.εapienε polyA εite DNA 1.8
448568 AA149121 Hs.71947 TM.LRRCT ESTs 1.8
439246 AI498072 Hs.77783 SS,TM,REJ,PLAT,PKD,WSC,LRRCT,GPSPMP22_Cla membrane-assxiated tyrosine- and threoni 1.8
410001 AB041036 Hs.57771 SSJM.trypsin kallikrein 11 1.8
417312 AW888411 Hs.81915 SS.Stathmin leukemia-aεsxiated phosphoprotein p18 (s 1.8 444152 AI125694 Hs.149305 TM hypothetical protein MGC2603 1.8
453454 AW052006 Hs.8551 TM PRP4/STK/WD splicing fxtor 1.8
449320 AB030835 Hs.23476 SS.adenylatekinase Cip1-interxting zinc finger protein 1.8
428329 AA426091 Hs.98453 TM.Gal-bind.lxtin ESTs, Moderately similar to R273282 [H.s 1.8
452875 BE275760 Hs.30928 TM.Apolipoproteinig DNA segment on chromosome 19 (unique) 117 1.8
444031 BE271513 Hs.25303 TM.Peptidase M10,hemopexin hypothetical protein FLJ 13154 1.8
443534 AI076123 TM gb:oy92e04.x1 Soares_fetalJiver_spleen_1 1.8
413313 NM 002047 Hs.75280 TM,WHEP-TRS,7tm_2 glycyl-tRN A synthetase 1.8
452874 AK001061 Hs.30925 SS hypothetical protein FLJ10199 1.8
453140 AA032238 Hs.170531 TM ESTs 1.8
418641 BE243136 Hs.86947 SS,TM,disintegrin,Pep M12B propep.Reprolyεin a disintegnn and metalloproteinase domai 1.8
432925 AA878324 Hs.192734 SS ESTs 1.8
453857 AL080235 Hs.35861 TM DKFZP586E1621 protein - 1.8
457663 AW371946 Hs.337459 TM ESTs 1.8
452873 AK001247 Hs.30922 TM hypothetical protein FU10385 1.8
436396 AI683487 Hs.152213 SS.wπt wingless-type MMTV integration site famil 1.8
452835 AK001269 Hs.30738 TM hypothetical protein FL) 10407 1.7
459647 R34107 Hs.198287 ig pregnancy spxific beta-1-glycoprotein 11 1.7
418245 AA088767 Hs.83883 TM.PEPCK transmembrane, prostate androgen induced 1.7
448484 BE613340 Hs.334725 TM Homo sapiens, Similar to RIKEN cDNA 94300 1.7
431369 BE184455 Hs.251754 SS.wap sxretory leuk∞y te proteaεe inhibitor (a 1.7
434877 AW974792 Hs.292171 TM ESTs 1.7
428923 BE047698 Hs.188785 TM ESTs 1.7
402915 NA TM.HC03 cotransp ENSP00000202587*:Bicarbonate transporter- 1.7
420185 AL044056 Hs.158047 TM ESTs 1.7
445739 AW136354 Hs.145303 TM ESTs 1.7
408435 AI810721 Hs.95424 TM,p450 ESTs 1.7
408688 AI634522 Hs.152925 TM KIAA1268 protein 1.7
420085 AI741909 Hs.44680 TM hypothetical protein FLJ20979 1.7
433933 AI754389 Hs.133494 TM,Ribosomal_S17Ribosomal_L13 Homo sapiens clone TCCCIA00164 mRNA seque 1.7
430965 AA489732 Hs.154918 hormone rec.Prog rxeptor,zf-C4 ESTs 1.7
414703 BE243877 Hs.76941 SS,TM,Na_K-ATPaseE2F_TDP ATPase, Na? transporting, beta 3 polypept 1.7
423464 NM 016240 Hs.128856 TM.Collagen CSR1 protein 1.7
416737 AF154335 Hs.79691 SS,TM,LIM,PDZsugar tr.PDZ.LIM UM domain protein 1.7
409012 AL117435 Hs.49725 TM,RhoGEFzf-DHHC,adh_short DKFZP434I216 protein 1.7
423804 AW403448 Hs.1706 TM.IRF interferon-sfimulated transcription fxto 1.7
410418 D31382 Hs.63325 SS,TM,trypεin,ldl rxepLa transmembrane protease, serine 4 1.7
440028 AW473675 Hs.125843 TM ESTs, Weakly similar to T17227 hypothetic 1.7
457646 AA725650 Hs.112948 TM.SPRY ESTs 1.7
445439 BE243084 Hs.12719 SSJGF-beta regulator of nonsenεe transcripts 1 1.7
420426 AA262045 Hs.36567 TM,Galxtosyl_T_2ATP-synLC Homo sapiens cDNA FLJ14227 fis, clone NT2 1.7
431341 AA307211 Hs.251531 TM.proteasome proteasome (prosome, mxropain) subunit, 1.7
412338 AA151527 Hs.69485 TM.Sema.Plexin repeatTIG,Plexin.repeat hypothetical protein FU12436 1.7
414799 AI752416 Hs.77326 SS.thyroglobulin 1.IGFBP insulin-like growth fxtor binding protei 1.7
452700 AI859390 Hε.288940 TM,DIX,RGS,thiored five-span transmembrane protein M83 1.7
430877 NM.005269 i Hs.2693 GST_C,tRNA-synL1,WHEP-TRS,TGF-beta glio a-asεxiated oncogene homolog (zinc 1.7
428624 AI125222 Hs.98712 TM,thiored,Y_phosphatase,MAM,ig,fn3MSP_domain hypothetical protein DKFZp434H0311 1.7
444065 AW449415 Hs.10260 TM.ioπ trans Homo εapiens cDNA F 11341 fis, clone PLA 1.7
416319 AI815601 Hs.79197 SS,TM,ig CD83 antigen (xtivated B lymphxytes, i 1.7
429367 AB007867 Hs.278311 Sema.Plexin repeatJIG plexin B1 1.7
430425 AA531428 Hs.241412 TM apolipoproteiπ L, 2 1.7
441668 AI611973 Hs.127525 TM,Ammonium_transp ESTs 1.7
418469 U34879 Hs.85279 SS,TM,adh short hydroxysteroid (17-beta) dehydrogenase 1 1.7
450835 BE262773 Hε.25584 TM,ArfGap hypothetical protein FU 10767 1.7
418859 AA229558 TM gb:no15d10.s1 NCI.CGAP.Pr1 Homo sapiens c ~' 1.7
425304 AA463844 Hs.31339 TM,ig,ITAM fibroblast growth fxtor 11 1.7
423635 X85019 Hs.130181 TM,Ricin_B_lxtin UDP-N-xetyl-alpha-D-galxtosamiπe:polyρe 1.7
414820 AA371931 Hs.77422 TM,ion_trans,UM,Synaptophyεin proteolipid protein 2 (colonic epithelium 1.7
440654 AW014242 Hε.159998 TM.conπexin ESTε 1.7
412276 BE262621 Hs.73798 SS.MIF mxrophage migration inhibitory fxtor (g 1.7
422087 X58968 Hs.111301 SS.Peptidase M10,fn2,hemopexin matrix metalloproteinase 2 (gelatinase A, 1.7
407151 H25836 Hs.301527 SSJNF ESTs, Moderately similar to unknown [H.sa 1.7
410726 AI623859 Hε.15936 TM.PX ESTs 1.7
452012 AA307703 Hs.279766 TM.kineεin kinesin family member 4A 1.7
433627 AF078866 Hs.284296 TM,SURF4,SURF1,DEADIip∞alin Homo sapienε cDNA: FU22993 fis, clone KA 1.7
409220 BE243323 Hs.51233 TM,death,TNFR_c6 tumor nxrosis fxtor rxeptor superfamil 1.7
427082 AB037858 Hs.173484 TM.mito carr hypothetical protein FU10337 1.7
426410 BE298446 Hs.305890 TM,Bcl-2,BH4 BCL2-like 1 1.7
433598 AI762836 Hs.271433 TM,Cytidylyltransf,SIR27tm_2 ESTs, Moderately similar to ALU2.HUMAN AL 1.7
436495 BE258948 Hs.290874 TM,Armadillo seg ESTs, Weakly similar to ALU8.HUMAN ALU SU 1.7
422032 AA476966 Hs.110857 TM,TFIIS,RNA POL_M_15KDseφin,hormone rx,zf-C4 polymerase (RNA) III (DNA directed) polyp 1.7
429736 AF125304 Hs.212680 SS,TNFR_c6 tumor nxfosiε fxtor receptor εuperfamil 1.7
427600 AW630918 Hs.179774 TM,Traπsglutamin_C,Traπsglutamin_N,Transglut_core proteasome (prosome, mxropain) xtivator 1.7
431981 AA664069 Hs.115779 laminin_B,laminin_EGF ESTs 17
407736 N41744 Hs.19978 TM.Sulfatase CGI-30 protein 1-7
420187 AK001714 Hs.95744 TM hypothetical protein similar to ankyrin r 1.7
424620 AA101043 Hs.151254 SSJM.trypεin kallikrein 7 (chymotryptic, stratum come 1.7
430488 D19589 Hs.13453 TM hypothetical protein FU14753 • 1.7
423393 R37772 Hε.21420 TM.thioredpkinase p21-xtivated protein kinase 6 1-7
444051 N48373 Hs.10247 SS,ig TABLE 13B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank xcession numbers
Pkey CAT Number Accesεions
408344 105240 1 AA053843 BE162213 418546 176677.1 AA224827 T59708 T59843 BE156903 418859 179717 1 AA229558 AA345492 AA229582 418869 179863 1 AW516565 AA229762 AA230035 437938 44573 2 AI950087 N70208 R97040 N36809 AI308119 AW967677 N35320 AI251473 H59397 AW971573 R97278 W01059 AW967671 AA808598 AA251875
AI820501 AI820532 W87891 T85904U71456T82391 BE328571 T75102 R34725 AA884922 BE328517 AI219788 AA884444 N92578 F13493
AA927794 AI560251 AW874068 AL134043 AW235363 AA663345 AW008282 AA488964 AA283144 AI890387 AI950344 AI741346 A1689062
AA282915 AW102898 AI872193 AI763273 AW173586 AW150329 AI653832 AI762688 AA988777 AA488892 AI356394 AW103813 AI539642
AA642789 AA856975 AW505512 AI961530 AW629970 BE612881 AW276997 AW513601 AW512843 AA044209 AW856538 AA180009 AA337499
AW961101 AA251669 AA251874 AI819225 AW205862 AI683338 AI858509 AW276905 AI633006 AA972584 AA908741 AW072629 AW513996
AA293273 AA969759 N75628 N22388 H84729 H60052 T92487 AI022058 AA780419 AA551005 W80701 AW613456 AI373032 AI564269 F00531
H83488 W37181 W78802 R66056 AI002839 R67840 AA300207 AW959581 T63226 F04005
438962 467390.1 BE046594 BE046667 AA828585 AI207343 443534 572957.1 A1076123 AI244834 AI695239 447197 711623.1 R36075 AI366546 R36167 454197 1050392 1 BE140966 BE140961 BE140967 BE141006 BE140985 BE140970 BE141669 BE141653 BE141664 BE141655 BE141661 BE141660 BE140969
BE141673 BE141650 BE141674 BE141550 BE141688 AW178241 BE140994 BE141666 BE140998 BE141008 BE140988 BE141011 BE140975
BE141667 BE141675 BE141657 BE141681 BE141656 BE141672 BE141680 AW178237 BE141012 BE140990 BE141658 BE141648 BE141013
BE141668 BE140973 BE141004 BE140963 BE140984 BE141009 AW178232 BE141007 BE141649 AW178293 BE140993 AW178233 BE141646
BE141005 BE141691 BE141000 BE141652 BE140965 BE141562 BE140960 BE140962 BE141001 BE140978 AW178229 AW178239 BE141671
AW178230 BE141547 AW178235 BE141663 BE141549 BE140996 BE141003 AW178236 BE141002 BE141556
455333 1281044.1 AW897851 AW897852 457570 357443.1 AA579426 AA579436 AA573736
TABLE 13C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numberε in this column are Genbank Identifier (Gl) numbers "Dunham I etal "referε to the publication entitled The DNA sequence of human chromosome 22 " Dunham 1 etal , Nature (1999) 402489-495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 400666 8118496 Plus 17982-18115,20297-20456
400749 7331445 Minus 9162-9283
401103 8568122 Minus 98330-98449
401486 7341763 Plus 32585-32756,36281-36540,40791-40933,44018-44179
401575 7229804 Minuε 76253-76364 402745 9212200 Minus 76516-76690
402915 7406502 Minus 140-276
404440 7528051 Plus 80430-81581
404604 9212537 Minus 72019-72509
405545 1054740 Plus 118677-118807,119091-119296,121626-121823 405547 1054740 Pluε 124361-124520,124914-125050
406400 9256298 Plus 1553-1712,1878-2140,42524385,59226077
406467 9795551 Plus 182212-182958
TABLE 14A 209 GENES UP-REGULATED IN CERVICAL CANCER COMPARED TO NORMAL ADULT TISSUES THAT ARE LIKELY TO ENCODE EITHER ENZYMES OR PROTEINS AMENABLE TO MODULATION BY SMALL MOLECULES
Table 14A lists about 209 genes up-regulated in cervical cancer compared to normal adult tisεues that are likely to encode either enzymes or proteins amenable to modulation by small molxules These were selxted as for Table 12A, except that the ratio was greater than or equal to 20, and the 96* percentile value amongst cervical cancers was greater than or equal 40 units, and the predicted protein contained a structural domain that is indicative of enzymatic function or of being moduiatable by small molxules (e g pkinase, peptidase, phosphatase, ATPase, or lon.transporter domains) The predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xceεεion number
UnigenelD Unigene number
PPDomams Predicted Protein Domains
Unigene Title Unigene gene title
R1 Ratio of tumor to normal adult tissues
Pkey ExAccn UnigenelD PPDomams Unigene Title R1
418007 M13509 Hs 83169 SS.hemopexin Peptιdase_M10 matnx metalloproteinase 1 (interst 389 439606 W79123 Hs 58561 TM,7tm_1 G protein-coupled rxeptor 87 288
400289 X07820 Hs 2258 hemopexιn,Peptιdase_M10 matnx metalloproteinase 10 (strome 205 415817 U88967 Hs 78867 SSJM Y_phosphatase,carb_anhyd protein tyrosine phosphatase, recep 164 416209 AA236776 Hs 79078 TM.HORMA MAD2 (mitotic arrest deficient, yea 154
404996 NM.001333 Hs 87417 Peptidase.CI CTSL2 Cathepsin L2 131 428618 AA885360 Hs 160199 pkinase Target CAT 127
429486 AF155827 Hs 203963 helicase C SNF2 Nhelicase C hypothetical protein FU10339 126
419183 U60669 Hs 89663 p450 cytxhrome P450, subfamily XXIV (vi 123
428368 BE440042 Hs 83326 SS,Peptιdase_M10,hemopexιn matnx metalloprotemase 3 (stromel 102
420759 T11832 Hs 127787 helicase C Homo sapienε cDNA FLJ11381 fis, clo 102
458194 AW383618 Hs 265459 p450 ESTs, Moderately similar to ALU2.HU 94
446232 AI281848 Hs 194691 TM,7tm_3Rιbosomal_L13 retinoic xid induced 3 89
424905 NM 002497 Hs 153704 TM pkinase NIMA (never in mitosis gene a) rela 89
452291 AF015592 Hs 28853 TM.pkmase CDC7 (cell division cycle 7, S cer 87
424086 AI351010 Hs 102267 Lysyl_oxιdase lyεyl oxidase 83
425710 AF030880 Hs 159275 TM,Sulfate_traπsp,STAS solute camerfamily, member 4 78
433133 AB027249 Hs 104741 TM,Collagen,pkιnaεe PDZ binding kinase, T-cell oπginat 74
447254 NM.004153 Hs 17908 SS,AAA,BAH oπgin recognition complex, subunit 71
431941 AK000106 Hs 272227 pkinase.Fuπn lιke,Rxep L do Homo sapiens cDNA FLJ20099 fis, clo 69
427821 AA470158 Hs 98202 TM,7tm_1 ESTs 69
436211 AK001581 Hs 334828 Ammomumjransp hypothetical protein FU10719, KIAA 69
403471 NA SSJM.trypsin Target Exon 67
410153 BE311926 Hs 15830 Glycos transf 2 hypothetical protein FU12691 65
457405 AA504860 TM,7tm_2 gb ab03a10 s1 Stratagene fetal reti 64
421948 L42583 Hs 334309 filament,HC03_cotranspfilament keratin 6A 63
439292 AA090421 Hs 5555 TM,AAA,Femc reduct hypothetical protein MGC5347 58
413625 AW451103 Hs 71371 TM E1-E2_ATPase,Hydrolase ESTs 58
425695 NM 005401 Hs 159238 TM,Band_41,Y_phosphataεe protein tyrosine phosphatase, non r 57
438394 BE379623 Hs 27693 SS.pro.iεomeraεe peptidylprolyl isomerase (cyclophil 56
432239 X81334 Hs 2936 SS.Peptidaεe M10,hemopexιn matnx metalloproteinase 13 (coliag 55
408536 AW381532 Hε 135188 SS,TM,E1-E2_ATPase,Catιon_ATPa ESTs 54
432226 AW182766 Hs 273558 Cytidylyltransf phosphate cytidylyltransferaεe 1, c 52
419520 AB009303 Hs 90800 TM,hemopexm,Peptιdaεe_M10 matnx melalloprotemase 16 (membra 51
426350 NM.003245 Hs 2022 TMJransglutamin.CJraπsglutam transglutammase 3 (E polypeptide, 50
421155 H87879 Hs 102267 SS,Lysyl_oxιdase,Aldose_epιm,E lysyl oxidase 49
423673 BE003054 Hs 1695 SSJM Peptιdase_M10,hemopexιn matnx metalloprotemase 12 (mxrop 48
450375 AA009647 Hs 8850 TM.disintegπn.Pep M12B propep a disintegnn and metalloprotemase 48
418379 AA218940 Hs 137516 AAA fidgetin like 1 47
457465 AW301344 Hs 122908 Pπbosyltran.Sulfatase DNA replication fxtor 46
412333 AW937485 TM,7tm_1 gb QV3-DT0044-221299-045-b09 DT0044 46
450510 AA010056 Hs 242998 DNA.topoisoll.DNAJopoisolVIGF ESTε 46
436291 BE568452 Hs 5101 abhydrolase protein regulator of cytokinesis 1 46
446353 AI290919 Hs 153661 HECTpkmase ESTs 45
435435 T89473 Hs 192328 lipase.PLAT ESTs 45
425071 NM 013989 Hs 154424 SS,TM,T4_deιodιnase deiodmase, lodothyronine, type II 44
433322 H50621 Hs 134156 TM.ionjransNB ARC,CARD,mιto_c ESTs, Weakly similar to I38022 hypo 44
408908 BE296227 Hs 250822 TM.pkmase seππe/threonine kinase 15 44
444781 NM.014400 Hs 11950 PH.Ixtamase.B GPI-anchored metastasis assxiated 44
428479 Y00272 Hs 184572 pkinase cell division cycle 2, G1 to S and 42
406687 M31126 Hs 272620 SS,Peptιdase_M10,hemopexιn pregnancy spxific beta-1-glycoprat 42
423035 AW449679 Hs 156739 TM.GIyco transf 8 H sapienε XG mRNA (clone PEP11) 42
449228 AJ403107 Hs 148590 TM,PAF-AH,p450 protein related with psoπasis 42
423738 AB002134 Hs 132195 SS,TM,trypsιn,SEA airway trypsin like protease 41
457030 AI301740 Hs 173381 TM.Dihydroorotase dihydropyπmtdinase-like 2 41
448995 AI613276 Hs 5662 adenylatekinaεe guanine nucleotide binding protein 40
415857 AA866115 Hs 127797 helicase.C Homo sapiens CDNA FU11381 fis, o 40
438390 AI422017 TM,DSL,7tm_17tm_1 gb tf45f12 x1 NCI CGAP_Brn23 Homo s 40
429900 AA460421 Hs 30875 pkinase ESTs 40
446292 AF081497 Hs 279682 Ammoniumjransp Rh type C glycoprotein 38
422938 NM.001809 Hs 1594 TM.thiolase centromere protein A (17kD) 37
408771 AW732573 Hε 47584 TM,K_tetra,ιon_frans potassium voltage-gated channel, de 36
424296 AI631874 Hs 155140 pkinase casein kinase 2, alpha 1 polypeptid 36
436246 AW450963 Hs 119991 connexιnhormone_rec,zf C4 ESTs 35
411274 NMJ02776 Hs 69423 trypsin kallikrein 10 35
400666 SS,hemopexιn,Peptιdase_M10 NM 002425 Homo sapiens matnx metal 35
426920 AA393351 Hs 132121 PDEase ESTs 35
412471 M63193 Hs 73946 SS,TM,Glycos_transf_3,Cam_xy endothelial cell growth fxtor 1 (p 34
430704 AW813091 Hs 335799 Epimerase ESTs 34
455092 BE152428 Sulfatase gb CM0-HT0323-151299-126-b04 HT0323 34
453775 NM.002916 Hs 35120 AAA,PI3_PI4_kιnase,PI3Ka,PI3K_ replication fxtor C (xtivator 1) 34
438993 AA828995 integππ.B gb od77b08 s1 NCI_CGAP_Ov2 Homo sap 34
426572 AB037783 Hs 170623 hormone rx,zf-C4 hypothetical protein FU11183 34
449101 AA205847 Hs 23016 SS,TM,7tm_1 G protein-coupled rxeptor 33
427660 A1741320 Hs 114121 hormone rec,zf-C4 Homo sapiens cDNA FU23228 fis, cl 33
402481 TM,GDI,7tm_1 NM.001821* Homo sapiens choroiderem 33
414774 X02419 Hs 77274 SS,kπngle,trypsιn plasmmogen xtivator, urokmase 33
412246 AI160873 Hs 69233 SulfotransferACOX zinc finger protein 33
418462 BE001596 Hs 85266 SS,TM,ιntegπn_B,fn3 integπn, beta 4 33
424687 J05070 Hs 151738 SS,Peptιdase_M10,fn2,hemopexιn matnx metalloprotemase 9 (gelatin 33
401486 NA SSJM.trypsin C4000647* gι|4758508|ref|NP_004253 32
408113 T82427 Hs 194101 TM,7tm 3Rιbosomal L13 Homo sapienε cDNA FU20869 fis, cl 32
427359 AW020782 Hε 79881 TM,7tm 1 Homo sapiens cDNA FU23006fis, cl 32
402337 SS,p450 Target Exon 32
420930 AW888650 πbonuclease_T2 gb CM4-NT0007-130500-551 -fOB NT0007 32
443426 AF098158 Hs 9329 pkinase chromosome 20 open reading frame 1 31
439750 AL359053 Hs 57664 TM,ιπtegππ_B,Rιcιn B Ixtinrr Homo sapiens mRNA full length inser 31
420039 NM 004605 Hs 94581 CARD.SulfotransferDAGKc sulfotransferase family, cytosolic, 30
448733 NM 005629 Hs 187958 SS,TM,SNF,ABC tran,ιsodh,pkιna εolute camerfamily 6 (neurotrans 30 444946 AW139205 Hs 156457 SSJM.abhydrolase hypothetical protein FU22408 30
450841 AI741466 Hs 270515 projsomerase ESTs 30
428262 AI651324 Hs 7298 death.pkinase biphenyl hydrolase-like (seπne hyd 30
435399 AA679463 pkinase gb ac50c03 s1 Stratageπe hNT neuron 29
446733 AA863360 Hs 26040 TM,p450 ESTs, Weakly similar to fatty xid 29
449746 AI668594 Hs 176588 SS,p450 ESTs, Weakly similar to CP4Y.HUMAN 29
418844 M62982 Hε 1200 SS,TM,lιpoxygenaεe,PLAT arxhidonate 12-lιpoxygenase 29
414581 AA256213 Hs 72010 TM.Cam xyltransf.Choline km ESTs 29
431629 AU077025 Hs 265827 SS,tRNA_antιSH2,SH3,pkιnase interferon, alpha-iπducible protein 28
445873 AA250970 Hs 251946 SS.rrm PABPpkιnase,14-3-3,rrm poly(A) binding protein, cytoplasmi 28
438113 AI467908 Hs 8882 TM,7tm_1 ESTs 28
422689 AW856665 helicase C.SNF2 Nhelicase C gb RC3-CT0297-290100-013-d03 CT0297 28
439453 BE264974 Hs 6566 SS.AAA thyroid hormone rxeptor interxtor 28
413582 AW295647 Hs 71331 carb anhydraεe hypothetical protein MGC5350 28
410664 NM.006033 Hs 65370 TM,lιpaεe,PLAT lipase, endothelial 28
456456 AA477609 Hs 89563 FBPase nuclear cap binding protein subunit 28
413273 U75679 Hs 75257 TM.ig.pkinase stem loop (histone) binding protein 28
426343 NM.014642 Hs 169387 TM,SCAN7tm_1 KIAA0036 gene product 28
403763 TM,7tm_1 NM.001059* Homo εapiens txhykinin 27
408380 AF123050 Hs 44532 TM,ubιquιtιn7tm_3,ANF_receptor diubiquitin 27
401230 SSJM lon.trans.lQ NM.014191* Homo sapiens sodium chan 27
418030 BE207573 Hs 83321 SS,TM,Peptιdaεe_S26,Bombesιn neuromedin B 27
445640 AW969626 Hs 31704 TM.alpha-amylase ESTs, Weakly similarto KIAA0227 [H 27
432865 AI753709 Hs 152484 TM,ιon_transNB ARC,CARD,WD40,m ESTs, Weakly similar to I38022 hypo 26
419667 AU077005 Hε 92208 SS,TM,dιsmtegπn,Reprolyειπ,P a disintegnn and metalloproteinase 26
406671 AA129547 Hs 285754 TM.pkinase.Plexm.repeat Sema, met proto-oncogeπe (hepatocyte grow 26
412530 AA766268 Hs 266273 abhydrolase hypothetical protein FU13346 26
431890 X17033 Hs 271986 vwa,FG-GAP,ιntegπn A integnn, alpha 2 (CD49B, alpha 2 s 26
404184 NA SS,TM,7tm_1 NM.030903* Homo sapiens olfactory r 26
428450 NM.014791 Hs 184339 pkιnase,KA1 KIAA0175 gene product 26
425698 NM 016112 Hε 159241 TM pkmase.ion.trans polycystic kidney disease 2-lιke 1 26
453331 AI240665 Hs 8895 TM,dιsιntegnn,Pep_M12B_propep ESTs 26
444826 AI674482 Hs 148441 pkiπase.SAM ESTε 26
414987 AA524394 Hs 294022 connexιnhormone_rx,zf-C4,conn hypothetical protein FU 14950 26
438746 AI885815 Hs 184727 Rιbosomal_S2,transferπn ESTε 25
429413 NM 014058 Hs 201877 trypsin DESC1 protein 25
407103 AA424881 Hs 256301 TM.cNMP.bindingtrypsin hypothetical protein MGC13170 25
453379 AA035261 Hs 61753 PAN,kπngle,trypsιn ESTs 25
421733 AL119671 Hs 1420 SS,TM,ιg,pkιπase fibroblast growth fxtor rxeptor 3 25
452220 BE158006 Hs 212296 TM,ιntegπn_A,FG-GAP ESTs 25
417975 AA641836 Hs 30085 SS.trypsin hypothebcal protein FU23186 25
400301 X03635 Hs 1657 TM.OesLr ep zf-C4,hormone_re estrogen rxeptor 1 25
408938 AA059013 Hs 22607 Y_phosphatase ESTs 24
411643 AI924519 Hs 192570 DEAD.helicase.C hypothetical protein FU22028 24
446638 AL133063 Hs 15783 TM.pkmase Homo sapiens mRNA, cDNA DKFZp434P11 24
430129 BE301708 Hs 233955 TM,Glyco_transf_11 hypothetical protein FU20401 24
417655 AA780791 Hs 14014 Peptιdase_M41.AAApkinase hypothetical protein FU14813 24
448005 AW207437 Hs 170378 pkinase ESTs 24
423973 AF038461 Hs 136574 TM.Iipoxygenase.PLAT arxhidonate 12-lιpoxygenase, 12Rt 24
437897 AA770561 Hs 146170 SS.pro.iεomerase hypothetical protein FU22969 24
425397 J04088 Hs 156346 DNA_topoιsoll,DNA_topoιsolVIGF topoisomerase (DNA) II alpha (170kD 24
432777 AA564991 Hs 269477 alpha-amylase ESTs 24
421247 BE391727 Hs 102910 TM,tRNA-synL1,SPRYF5_F8_type_ general transcnption fxtor HH, p 24
425465 L18964 Hs 1904 TM,pkιnase,DAG_PE-bιnd,OPR,pkι protein kinase C, iota 24
419281 H96452 Hs 42189 TM.E1-E2 ATPase,HMA,Hydralase ESTs 24
434205 AF119861 Hs 283032 SH3,efhand,C2,PH,RhoGEF,AAA,PG hypothetical protein PRO2015 24
453406 AI192987 Hs 61784 pkmase.Fuπn lιke,Rxep_L_dom hypothetical protein FU14451 23
435542 AA687376 Hs 269533 pkιnase,RhoGEF,ιg,PH,SH3 ESTs 23
443151 AI827193 Hs 132714 DNA.mis.repair.HATPase.cAcylph ESTs 23
431630 NM.002204 Hs 265829 SS,TM,FG-GAP,ιntegπn_A integπn, alpha 3 (antigen CD49C, a 23
422310 AA316622 Hs 98370 SS,TM,fn3,ιg,pkιnase,Rιbosomal cytochrome P450, subfamily IIS, pol 23
441954 AI744935 Hs 8047 TM,Baπd_7,AAA,cdc48_N Fanconi anemia, complementation gro 23
414907 X90725 Hs 77597 SS,TM,pkιnase,POLO_box polo (Drosophiaj-like kinase 23
439810 AL109710 Hs 85568 xonιtase,Acoπιtaεe_C EST 23
429359 W00482 Hε 2399 SS,TM,Peptιdase_M10,hemopexιn matnx metalloproteinase 14 (membra 23
432284 AA532807 Hε 105822 TM.pkmase ESTs 23
452947 AW130413 alpha-amylase gb xf50f04 x1 NCI_CGAP_Gas4 Homo sa 23
423229 AC003965 Hs 125532 SS.trypsin protease, seπne, 26 23
453941 U39817 Hs 36820 DEAD.HRDC.helicase C Bl∞m syndrome 23
439963 AW247529 Hs 6793 TM,p450Ets platelet-activating fxtor xetylhy 23
424439 AA579635 Hs 1770 DNAJigase ligase I, DNA, ATP-depeπdent 22
452755 AW138937 Hs 213436 Glyco_transf_29 ESTs, Weakly similar to A34087 hypo 22
429922 Z97630 Hs 226117 TM,lιπker_hιstone7tm 1 H1 histone family, member 0 22
434149 Z43829 Hs 19574 TM.EPH lbd,fn3,pkιnase,SAM hypothetical protein MGC5469 22
417576 AA339449 Hs 82285 TM AIRS,formyl_transf,GARS phosphonbosylglycinamide formyltra 22
409994 D86864 Hs 57735 IP_transSH2,SH3 xetyl LDL receptor; SREC 22
416763 AI908127 Hs 79748 TM,alpha-amylase7tm_1 solute earner family 3 (xtivators 22
414733 BE514535 Hs 77171 TM.MCMHeme oxygenase minichromoεome maintenance deficien 22
443171 BE281128 Hs 9030 SS,TM,7tm_1,rrm TONDU 22
430637 BE160081 Hs 256290 S_100Peptιdase_M16 S100 calcium-binding protein A11 (c 22
452367 U71207 Hs 29279 SS.Hydralaεe eyes absent (Drasophila) homolog 2 22
408308 AL033377 Hs 44197 TM,7tm_2 hypothetical protein DKFZp564D0462 22
417900 BE250127 Hε 82906 TM,WD40,pro_isomerase CDC20 (cell division cycle 20, S c 21 424490 AJ278016 Hs.55565 TM.pkinase.ank ankyrin repeat domain 3 2.1
412834 R77123 Hs.79881 TM,7tm_1 Homo sapienε cDNA: FU23006 fiε, cl 2.1
410855 X97795 Hs.66718 SNF2 N.helicase C RAD54 (S.cerevisiae)-lιke 2.1
418804 AA809632 HATPase_c,HSP90,PHD,zf-C2H2 gb:nz17h04.s1 NCI.CGAP.GCB1 Homo εa 2.1
447674 BE270640 Hs.19192 TM.pkinaseras.arf cyclin-dependent kinase 2 2.1
450663 H43540 Hs 25292 SSJM.RNase.HII ribonuclease HI, large subunit 2.1
408805 H69912 Hs.48269 TM.pkinase vxcinia related kinase 1 2.1
429415 NM 002593 Hs.202097 SS,CUB,NTR,MAM,TIL,TILa,vwd,EP procollagen C-endopeptidase enhance 2.1
447827 U73727 Hs.19718 SS,TM,Y_phosphatase,fn3,ig,MAM protein tyrosine phosphatase, rxep 2.1
428273 AI867228 Hs.303211 Glycos_transf_2 ESTs 2.1
404274 SS,TM,pkinase,fn3 NM_002944*.Homo sapiens v-ros avian 2.1
403133 pkinase,K_tetra,Baπd 41,RhoGEF Target Exon 2.1
440249 AI246590 Hs.337275 VHLJatD.DNaεe ESTs 2.1-
438580 AA811262 Hs.299202 TM.pkiπasesugar.tr ESTs 2.1
406400 SSJM.trypsin NM_007196.Homo sapiens kallikrein 8 2.1
427375 AL035460 Hs.177536 SS,Zn_carbOpept,hormone5Reprol metaltocarboxypeptidase CPX-1 2.1
423453 AW450737 Hs.128791 SS,Granin,CDP-OH_P_transf CGI-09 protein 2.1
433716 AA608808 Hs.225118 Acylphosphatase ESTs 2.1
420757 X78592 Hs.99915 TM,hormoπe_rec,Androgen_recep, androgen rxeptor (dihydrotestoεter 2.1
425018 BE245277 Hs.154196 DNaεe l,K_tetra E4F transcription fxtor 1 2.1
421685 AF189723 Hs.106778 TM,E1-E2_ATPaεe,HydrolaseE1-E2 ATPase, Ca transporting, type 2C, m 2.1
457288 AA521458 Hs.192738 pro.isomerase ESTs 2.1
407305 AA715284 TM,pkinase,Sema,Plexin_repeat, gb:nv35f03.r1 NCI.CGAP.Br5 Homo sap 2.1
456327 H68741 Hε.38774 TM,Glyco_transf_8 ESTs 2.0
422429 AA310527 pkinase,RGS,PHpkinase,PH,RGS gb:EST181333 JurkatT-cells V Homo 2.0
402974 NM 001501 Hs.129715 GnRHhormone5,hormone4 gonadotropin-releasing hormone 2 2.0
458016 AW188099 Hs.131813 pkinase ESTs 2.0
452194 AI694413 Hs.332649 TM,7tm_3,ANF_rxeptor,8Uεhi olfxtory rxeptor, family 2, subfa 2.0
428028 U52112 Hs.182018 TM.pkinase.MBD interieukin-1 rxeptor-ass∞iated k 2.0
427747 AW411425 Hs.180655 pkinaseJipoxygenase.PLATIipox seriπe/threonine kinase 12 2.0
452841 T17431 Hs.65412 TM,DEAD,helicaεe_C DEAD/H (Asp-Glu-Ala-Asp/Hiε) box po 2.0
449539 W80363 Hε.58446 pkinase.Furiπ-like.Recep L dom ESTε 2.0
418140 BE613836 Hs.83551 TM.E1-E2 ATPase microfibrillar-assxiated protein 2 2.0
430076 AA465115 Hs.318773 AAA.BAH KIAA1836 protein 2.0
425749 AW328587 Hs.159448 Ribosomal_L7Ae,LRR,LRRCT,pkina surfeit 2 2.0
425855 AF135025 Hs.159679 SS.trypsin kallikrein 12 2.0
400135 L40027 Hs.118890 pkinase glycogen synthaεe kinase 3 alpha 2.0
TABLE 14B
Pkey: Unique Eos probeset identifier number
CAT number Gene cluster number Accession: Genbank accesεion numbers
Pkey CAT number Acceεsions
412333 1289037 1 AW937485 AW937589 AW937658 AW937654 AW937492 418804 179138 1 AA809632 AI917245 AI701732 AA228406 420930 197736 1 AW888650 AW888651 BE149946 BE149948 BE149951 BE149947 AW888649 AA281840 AA281822 AW888652 422429 216469.1 AA310527 AW962295 Z44865 H06641 422689 219896 1 AW856665 AA315006 AW954733 435399 405576.1 AA679463 AW813779 AW813709 438390 45662.1 AI422017 AI422945 AI363249 AI423113 AI925592 AI420795 AI208187 AI423279 AI423645 AI424090 AI359637 AL044732 D17003 438993 467651 1 AA828995 AA834879 AI926361 452947 939810 1 AW130413AI932362 455092 1252971.1 BE152428 AW855572 AW855607 457405 333127.1 AA504860 AA504911
TABLE 14C
Pkey: Unique number corresponding to an Eos probeset
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489495.
Strand: Indicates DNA strand from which exons were predicted.
NLposition: Indicates nucleotide positionε of predicted exonε.
Pkey Ref Strand NLpoεition
400666 8118496 Plus 17982-18115,20297-20456
401230 9929527 Minus 33835-34006,34539-34592,36461-36745,4892549098,52604-52758
401486 7341763 Plus 32585-32756,36281-36540,4079140933,4401844179
402337 6957691 Plus 4116-4286,16811-16973,17107-17256,19715-20040,22029-22205
402481 9797406 Plus 87891-88991
403133 7331427 Plus 38314-38634
403471 9930659 Minus 85867-85983
403763 7229888 Minus 4357543887
404184 4581418 Minus 12652-13548
404274 9885189 Plus 104127-104318
406400 9256298 Pluε 1553-1712,1878-2140,42524385,5922-6077 TABLE 15A: 752 GENES UP-REGULATED IN CERVICAL CANCER COMPARED TO NORMAL ADULT CERVIX
Table 15A lists about 752 genes up-regulated in cervical cancer compared to normal adult cervix. Theεe were εelxted as for Table 12A, except that the ratio was greater than or equal to 7.0, the denominator was the median value for three non-malignant cervical spximens, and the 96 percentile value amongst cervical cancers waε greater than or equal 80 units.
Pkey: Unique Eos probeset identifier number
ExAccn: Exemplar Accession number, Genbank accession number UnigenelD: Unigene number Unigene Title: Unigene gene title R1 : Ratio of cervical cancer to nomial cervix
Pkey ExAccn UnigenelD Unigene Title R1
414915 NM 002462 Hs.76391 myxovirus (influenza) resistance 1, homolog of murine 58.3
411248 AA551538 Hs.334605 Homo sapiens cDNA FLJ14408 fis, clone HEMBA1004341 36.2
428227 AA321649 Hs.2248 small inducible cytokine subfamily B (Cys-X-Cys), mem 35.6
421508 NM 004833 Hs.105115 absent in melanoma 2 33.6
443639 BE269042 Hs.9661 proteasome (prosome, mxropain) subunit, beta type, 1 32.0
454390 AB020713 Hs.56966 KIAA0906 protein 30.5
416065 BE267931 Hs.78996 proliferating cell nuclear antigen 30.4
433226 AW503733 Hs.9414 KIAA1488 protein 30.0
413503 BE410228 Hs.75410 heat sh∞k 70kD protein 5 (glucose-regulated protein, 29.4
411669 BE612676 Hε.303116 stromal cell-derived fxtor 2-like 1 28.9
414132 AI801235 Hε.48480 ESTs 28.3
422809 AK001379 Hs.121028 hypothetical protein FU10549 28.1
448569 BE382657 Hs.21486 signal transducer and xtivator of transcription 1, 9 27.4
432906 BE265489 Hs.3123 lethal giant larvae (Drasophila) homolog 2 27.2
418963 BE304571 Hs.89529 aldo-keto reductase family 1 , member A1 (aldehyde red 26.9
439963 AW247529 Hε.6793 platelet-activating fxtor xetylhydrolase, isoform I 26.5
449722 BE280074 Hs.23960 cyclin B1 26.2
414812 X72755 Hs.77367 monokine induced by gamma interferon 25.3
408405 AK001332 Hs.44672 hypothetical protein FU10470 25.1
432917 NM.014125 Hs.279812 PRO0327 protein 24.6
412530 AA766268 Hε.266273 hypothetical protein FLJ13346 23.6
457465 AW301344 Hs.122908 DNA replication fxtor 23.1
408806 AW847814 Hs.289005 Homo sapiens cDNA: FU21532 fis, clone COL06049 22.9
429083 Y09397 Hs.227817 BCL2-related protein A1 22.9
401405 Target Exon 22.8
426272 AW450671 Hs.189284 ESTs 22.7
424878 H57111 Hs.221132 ESTs 22.6
412140 AA218691 Hs.73625 RAB6 interacting, kinesin-like (rabkinesin 6) 22.5
444371 BE540274 Hs.239 forkhead box M1 22.2
418030 BE207573 Hs.83321 πeuromedin B 22.0
452291 AF015592 Hs.28853 CDC7 (cell division cycle 7, S. cerevisiae, homolog)- 21.6
400196 Eoε Control 21.3
416795 A1497778 Hs.20509 HBV pX aεsxiated protein-8 21.2
424865 AF011333 Hs.153563 lymph∞yte antigen 75 21.0
438011 BE466173 Hs.145696 splicing fxtor (CC1.3) 20.7
428368 BE440042 Hε.83326 matrix metalloproteinase 3 (stromelyεin 1, progelatin 20.3
436923 AW293704 Hs.122658 ESTs 20.2
415791 H09366 Hs.78853 uracil-DNA glycoεylase 20.0
448775 AB025237 Hs.388 nudix (nucleoside diphosphate linked moiety X)-type 19.6
435647 A1653240 Hε.49823 ESTs 19.6
431049 AA846576 Hs.103267 hypothetical protein FU22548 similar to gene trap PA 19.5
429486 AF155827 Hs.203963 hypothetical protein FU10339 19.5
428433 AA521410 Hs.41371 ESTs 19.4
418322 AA284166 Hs.84113 cyclin-dependent kinase inhibitor 3 (CDK2-associated 19.3
417308 H60720 Hs.81892 KIAA0101 gene product 19.2
429574 BE268321 Hs.208912 hypothetical protein MGC861 19.2
407204 R41933 Hε.140237 ESTs, Weakly similar to ALU1.HUMAN ALU SUBFAMILY J SE 19.0
408901 AK001330 Hε.48855 hypothetical protein FU10468 19.0
438899 AF085833 Hs.135624 ESTs 19.0
456362 AW973003 Hs.179909 hypothetical protein FU22995 18.9
438598 AI805943 Hs.326067 hypothetical protein MGC5178 18.8
408908 BE296227 Hs.250822 serine/threonine kinase 15 18.8
427488 M91401 Hs.178658 RAD23 (S. cerevisiae) homolog B 18.6
400195 NM_007057*:Homo sapiens ZW10 interactor (ZWINT), tran 18.5
414747 U30872 Hs.77204 centromere protein F (350/400kD, mitosin) 18.4
410324 AW292539 Hs.30177 ESTs 18.3
453028 AB006532 Hs.31442 R∞Q protein-like 4 18.1
410608 AI538438 Hs.159087 ESTs 18.1
432503 AA551196 Hs.188952 ESTs 17.9
430512 AF182294 Hs.241578 U6 snRNA-associated Sm-like protein LSm8 17.7
430709 R34356 gb:yh85d01.ε1 Soares placenta Nb2HP Homo sapiens cDNA 17.6
449962 AA004879 Hs.187820 ESTs 17.3
425408 AB002375 Hs.156814 KIAA0377 gene product 17.1
440774 AI420611 Hs.127832 ESTs 16.8
408201 AK000568 Hs.43654 hypothetical protein FU20561 16.7
436110 AA704899 Hs.291651 ESTs, Weakly similarto I38022 hypothetical protein [ 16.7
426897 AW976570 Hs.97387 ESTs 16.5
447700 AI420183 Hs.171077 ESTs, Weakly similarto T21259 hypothetical protein F 16.5 433159 AB035898 Hε.150587 kinesin-like protein 2 16.3
430466 AF052573 Hε.241517 polymerase (DNA directed), theta 16.3
453883 AI638516 Hs.22630 cofactor required for Sp1 transcriptional xtivation, 16.3
453941 U39817 Hs.36820 Bloom syndrome 16.1
438461 AW075485 Hs.286049 phosphoseriπe aminotransferase 16.0
407999 AI126271 Hs.49433 ESTs, Weakly similar to YZ28 HUMAN HYPOTHETICAL PROTE 16.0
413943 AW294416 Hs.144687 Homo sapiens cDNA FU12981 fis, clone NT2RP2006454 157
407720 AB037776 Hs.38002 KIAA1355 protein 156
425316 AA354977 Hs.191565 ESTs, Moderately similar to T14342 NSD1 protein - mou 15.6
423673 BE003054 Hs.1695 matrix metalloproteinase 12 (mxrophage elastase) 15.5
419777 D60134 Hs.270975 ESTs 15.3
453886 R66282 Hs.20247 ESTs, Weakly similar to S65657 alpha-1 Cadrenergic re 15.2
443715 AI583187 Hs.9700 cyclin E1 15.2
407786 AA687538 Hε.38972 tetraspan 1 15.2
431910 AK000142 Hε.101774 hypothetical protein FU23045 15.2
417634 W27202 Hs.82327 glutathione synthetase 15.1
432692 AW974944 Hs.200577 ESTs 15.1
446921 AB012113 Hs.16530 small inducible cytokine subfamily A (Cys-Cys), membe 15.1
427999 AI435128 Hs.181369 ubiquitin fusion degradation 1-like 15.0
413869 NM.000878 Hs.75596 interleukin 2 rxeptor, beta 15.0
431629 AU077025 Hs.265827 interferon, alpha-inducible protein (clone IFI-6-16) 14.9
435354 AA678267 Hs.117115 ESTs 14.8
406836 AW514501 Hε.156110 immunoglobulin kappa constant 14.8
416109 AI420311 Hs.126550 suppressor of K transport defxt 1 14.8
417933 X02308 Hs.82962 thymidylate synthetase 14.7
438970 AA837782 Hs.321058 ESTs 14.7
409680 W31092 Hε.55847 mitochondrial ribosomal protein 64 14.7
432401 NM 013330 Hs.274479 NME7 14.6
425397 J04088 Hs.156346 topoisomerase (DNA) II alpha (170kD) 14.5
420734 AW972872 Hs.293736 ESTs 14.5
434256 AI378817 Hs.191847 ESTs 14.5
418269 AA806113 Hs.189025 ESTs 14.3
427372 AW960673 Hs.177530 ATP synthaεe, H transporting, mit∞hondrial F1 comple 14.3
427081 AI474533 Hε.170528 ESTs, Moderately similar to ALUC HUMAN HI! ALU CLASS 14.2
420309 AW043637 Hε.21766 ESTs, Weakly similar to ALU5.HUMAN ALU SUBFAMILY SC S 14.2
429966 BE081342 Hε.283037 HSPC039 protein 14.2
410361 BE391804 Hε.62661 guanylate binding protein 1, interferon-iπducible, 67 14.1
443957 AA521049 Hε.34487 hypothetical protein FU23412 14.0
418803 U50079 Hε.88556 histone dexetylaεe l 14.0
434094 AA305599 Hε.238205 hypothetical protein PRO2013 14.0
420139 NM.005357 Hs.95351 lipase, hormone-sensitive 13.9
444783 AK001468 Hs.62180 anillin (Drasophila Scraps homolog), xtin binding pr 13.9
433255 AI274270 Hs.96840 KIAA1527 protein 13.9
431838 AI097229 Hs.217484 ESTε, Weakly similar to ALU1.HUMAN ALU SUBFAMILY J SE 13.8
449801 AA477355 Hs.288300 hypothetical protein FU23231 13.8
447078 AW885727 Hs.301570 ESTs 13.8
441240 AA923749 Hε.132442 ESTs 13.8
439398 AA284267 Hs.221504 ESTs 13.6
404630 Target Exon 13.6
408321 AW405882 Hs.44205 cortistatin 13.6
426427 M86699 Hs.169840 TTK protein kinase 13.5
413278 BE563085 Hs.833 interferon-stimulated protein, 15 kDa 13.5
403055 C2002219*:gi|12737280|ref|XP_006682.2| keratin 18 [Ho 13.5
456614 AV653110 Hs.106650 hypothetical protein FU20533 13.5
425261 BE385099 Hs.334727 hypothetical protein MGC3017 13.3
439926 AW014875 Hs.137007 ESTε 13.3
411263 BE297802 Hs.69360 kineεin-like 6 (mitotic centromere-aεε∞iated kineεin 13.2
451141 AW772713 Hs.247186 ESTs 13.2
447380 X95384 Hs.18426 translational inhibitor protein p14.5 13.2
419828 T81422 Hs.14922 ESTs 13.2
428147 AW629965 Hε.234983 ESTs, Weakly similar to 2109260A B cell growth fxtor 13.2
410068 AI633888 Hs.58435 FYN-binding protein (FYB-120/130) 13.1
407595 BE350012 Hs.248365 ESTs 13.1
432721 AL121478 Hs.180532 glucose phosphate isomerase 13.1
416975 NM.00413- I Hs.1051 granzyme B (granzyme 2, cytotoxic T-lymphxyte-ass∞i 13.0
413314 BE081585 gb:QV2-BT0635-210400-156-b07 BT0635 Homo sapienε cDNA 13.0
430929 AA489166 Hs.156933 ESTε 12.9
449571 AW016812 Hε.200266 ESTs 12.9
400298 AA032279 Hε.61635 six transmembrane epithelial antigen of the prostate 12.8
417105 X60992 Hs.81226 CD6 antigen 12.6
434263 N34895 Hs.44648 ESTs 12.6
412059 AA317962 Hs.249721 ESTs, Moderately similar to PC4259 ferritin asεxiate 12.6
407756 AA116021 Hs.38260 ubiquitin εpxific protease 18 12.5
437056 AI147061 gb:ok33a11.s1 Soareε NSF F8.9W.OT PA P S1 Homo εapieπ 12.5
438768 AI307416 Hε.184675 ESTε, Moderately similar to ALU7.HUMAN ALU SUBFAMILY 12.5
444478 W07318 Hs.240 M-phase phosphoprotein 1 12.5
450738 AA010907 Hs.184456 hypothetical protein 12.4
418205 1-21715 Hs.83760 troponin 1, skeletal, fast 12.4
442994 AI026718 Hs.16954 ESTs 12.4
433301 AW296280 Hs.152016 Homo sapiens cDNA: FU22140 fis, done HEP20977 12.4
437457 AA757900 Hs.270823 ESTs, Weakly similar to S65657 alpha-1 C-adrenergic re 12.4
435327 BE301871 Hs.4867 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acety!g 12.3
422765 AW409701 Hs.1578 bxuloviral IAP repeat-containing 5 (survivin) 12.3 410245 C17908 Hs.194125 ESTs 12.3
424927 AW973666 Hs.153850 hypothetical protein C321D2.4 12.3
418941 AA452970 Hs.155218 E1B-55kDa-assxiated protein 5 12.3
432325 AW973209 Hs.261782 ESTs 12.3
414761 AU077228 Hε.77256 enhancer of zeste (Drasophila) homolog 2 12.3
418618 U66097 Hs.86724 GTP cyclohydralase 1 (dopa-responsive dystonia) 12.2
449296 AL137257 Hs.23458 Homo sapiens cDNA: FU23015 fis, clone LNG00818 12.2
415857 AA866115 Hs.127797 Homo sapiens cDNA FU11381 fis, clone HEMBA1000501 12.2
427295 AW291212 Hs.293943 hypothetical protein MGC11266 12.2
415443 T07353 Hs.7948 ESTs 12.1
429770 AI766047 Hs.99736 ESTs 12.1
428955 AA579297 Hs.26937 brain and πasopharyngeal carcinoma susceptibility pro 12.1
435244 N77221 Hs.187824 ESTs 12.1
432810 AA863400 Hs.23054 ESTs 12.1
434423 NM.006769 Hs.3844 UM domain only 4 12.0
443378 AW392550 Hs.9280 proteasome (prosome, mxropain) subunit, beta type, 9 12.0
459273 AW608906 Hs.334767 hypothetical protein MGC5629 12.0
418945 AW290975 Hs.118923 ESTs 11.9
442159 AW163390 Hs.278554 heterochramatin-like protein 1 11.9
436169 AA888311 Hs.17602 Homo sapiens cDNA FLJ12381 fis, clone MAMMA1002566 11.9
407804 AF228603 Hs.39957 plxkstrin 2 (mouse) homolog 11.8
401557 Target Exon 11.8
434408 AI031771 Hs.132586 ESTs 11.8
406747 AI925153 Hs.217493 annexin A2 11.8
409231 AA446644 Hs.692 GA733-2 antigen; epithelial glycoprotein (EGP) (KSA) 11.8
429412 NM.006235 Hs.2407 POU domain, claεε 2, assxiating fxtor 1 11.8
445655 AA873830 Hε.167746 B cell linker protein > 11.7
419138 U48508 Hs.89631 ryanodine rxeptor 1 (skeletal) 11.7
427527 AI809057 Hs.302063 immunoglobulin heavy constant mu 11.7
432287 AK001057 Hε.274268 Homo εapienε cDNA FU10195 fiε, clone HEMBA1004771 11.6
408548 AA055449 Hs.63187 ESTs, Weakly similar to ALUC.HUMAN III! ALU CLASS C W 11.6
409703 NM.006187 Hs.56009 2'-5'-oligoadenylate synthetase 3 (100 kD) 11.6
447082 T85314 Hs.42644 thioredoxin-like 11.5
409931 BE293233 Hs.129771 ESTs 11.4
426172 AA371307 Hs.125056 ESTs 11.4
424723 BE409813 Hs.152337 protein arginine N-methyltransferase 3(hnRNP methyltr 11.4
456880 AW015644 Hs.155005 TEA domain family member 1 (SV40 transcriptional enha 11.4
433849 BE465884 Hs.280728 ESTs 11.4
430519 AF129534 Hs.49210 F-box only protein 4 11.4
434442 AA737415 Hs.152826 ESTs 11.3
457205 AI905780 Hs.198272 Target CAT 11.3
422713 AA902780 Hs.119325 Huntingtin-interacting protein A 11.3
443491 AW499665 Hs.9456 SWI/SNF related, matrix aεsxiated, xtin dependent r 11.3
424339 BE257148 Hs.145416 endoglycan 11.3
419741 NM 007019 Hs.93002 ubiquitin carrier protein E2-C 11.3
450208 AI686945 Hs.272062 ESTs 11.2
446849 AU076617 Hε.16251 cleavage and polyadenylation spxific fxtor 3, 73kD 11.2
424965 AW956282 Hs.144609 Homo sapiens, Similar to RIKEN cDNA 5730578N08 gene, 11.2
442737 AB002319 Hs.8663 KIAA0321 protein 11.2
409113 AA074897 gb:zm85a05.r1 Stratagene ovarian cancer (937219) Homo 11.2
415782 AA169345 Hε.123177 ESTs 11.1
417958 AA767382 Hs.193417 ESTs 11.1
402539 AW502761 Hs.30909 KIAA0430 gene product 11.0
413677 AW503116 Hs.301819 zinc finger protein 146 11.0
414706 AW340125 Hs.76989 KIAA0097 gene product 11.0
421632 AA825426 Hs.238832 ESTs,Weakly similartoALU1 HUMAN ALU SUBFAMILY J SE 11.0
438995 AI277986 Hs.164875 ESTs 11.0
400289 X07820 Hs.2258 matrix metalloproteinase 10 (stromelyεin 2) 10.9
432363 AA534489 gb:nf76g11.ε1 NCI CGAP Co3 Homo sapiens cDNA clone 3' 10.9
451655 H85689 Hs.225560 ESTs 10.9
429237 AA448417 Hs.104990 ESTs 10.9
427719 AI393122 Hs.134726 ESTs 10.9
444665 BE613126 Hε.47783 B aggreεsive lymphoma gene 10.8
410093 AW589558 Hs.296120 ESTs, Weakly similar to KIAA0970 protein [H.sapiens] 10.8
400080 Eos Control 10.8
424517 AI539443 Hs.137447 Homo sapiens cDNA FU12169 fis, clone MAMMA1000643 10.8
401539 NM_002675:Homo sapiens promyel∞ytic leukemia (PML), 10.8
446099 T93096 Hs.17126 hypothetical protein MGC15912 10.7
451066 AI758660 Hs.206132 ESTs 10.7
409235 AA188827 Hs.7988 ESTs, Weakly similar to I38022 hypothetical protein [ 10.7
451730 AF095687 Hs.26937 brain and nasopharyngeal carcinoma susceptibility pro 10.7
428054 AI948688 Hs.266619 ESTs 10.6
441636 AA081846 Hs.7921 Homo sapienε mRNA; cDNA DKFZp566E183 (from clone DKFZ 10.6
438654 AI005270 Hs.123543 ESTs 10.6
424321 W74048 Hs.1765 lymphxyte-spxific protein tyrosine kinase 10.6
449035 AI815728 Hs.19980 DNA polymerase epsilon p12 subunit 10.6
436137 AI056769 Hε.133512 ESTs 10.6
417863 AB000450 Hε.82771 vaccinia related kinase 2 10.6
439975 AW328081 Hε.6817 inoεine triphoεphataεe (nucleoεide triphosphate pyrop 10.6
434206 AW136973 Hs.288516 ESTs, Weakly similar to S69890 mitogen inducible gene 10.6
454355 AW812535 gb:CM4-ST0182-051099-021-c09 ST0182 Homo sapiens cDNA 10.6
435542 AA687376 Hs.269533 ESTs 10.6
431386 AA504359 Hs.110067 ESTs, Weakly similar to ALU5.HUMAN ALU SUBFAMILY SC S 10.5 416564 AW795793 Hs.179827 Homo sapiens cDNA FLJ12257 fis, clone MAMMA1001501, h 10.5
447769 AW873704 Hε.320831 Homo sapiens cDNA FLJ14597 fis, clone NT2RM4002390 10.5
408329 AF155510 Hs.44227 heparanase 10.5
410146 AW592655 gb:hf45f12.x1 Soares.NFLT_GBC.S1 Homo sapienε cDNAc 10.5
427600 AW630918 Hs.179774 proteasome (prosome, mxropain) xtivator subunit 2 ( 10.4
418007 M13509 Hs.83169 matrix metalloproteinase 1 (interstitial collagenase) 10.4
407241 M34516 gb:Human omega light chain protein 14.1 (Ig lambda ch 10.4
435061 AI651474 Hs.163944 ESTε 10.4
409653 AW451693 Hs.220826 ESTε 10.4
428294 AA425488 gb:zw46d02.r1 Soares_total_fetus_Nb2HF8_9w Homo sapie 10.4
433160 AW207002 Hs.134342 TASP for testiε-εpecific adriamycin sensitivity prate 10.4
408809 AW274673 Hs.279706 ESTs, Weakly similar to A47582 B-cell growth fxtor p 10.4
410174 AA306007 Hs.59461 DKFZP434C245 protein 10.4
424792 U92538 Hs.153138 origin rxognition complex, subunit 5 (yeast homolog) 10.3
422406 AF025441 Hs.116206 Opa-interxting protein 5 10.3
424687 J05070 Hs.151738 matrix metalloproteinase 9 (gelatinase B, 92kD gelati 10.3
413809 L25851 Hs.851 integrin, alpha E (antigen CD103, human mucosal lymph 10.3
413507 BE145360 Hs.190064 ESTs, Weakly similar to 138022 hypothetical protein [ 10.3
448119 H38587 Hs.82295 dedicator of cyto-kinesiε 1 10.2
457288 AA521458 Hs.192738 ESTs 10.2
402025 NM_021624:Homo sapiens histamine H4 receptor (HRH4), 10.2
440572 AW183778 Hs.249584 ESTs, Weakly similarto MYSA.HUMAN MYOSIN HEAVY CHAIN 10.2
453323 AF034102 Hs.32951 solute carrier family 29 (nucl∞side transporters), m 10.2
443780 NM.012068 Hs.9754 xtivating transcription fxtor 5 10.1
422429 AA310527 gb:EST181333 JurkatT-cells V Homo sapienε cDNA 5' en 10.1
444314 AI140497 gb:ow76b09.s1 Soares_fetal_liver_εpleen_1NFLS_S1 Homo 10.1
426125 X87241 Hs.166994 FAT tumor εuppressor (Drasophila) homolog 10.1
430848 AW021726 gb:df27e02.y1 Morton Fetal Cochlea Homo sapienε cDNA 10.1
422470 AB017919 Hs.117232 peptidyl arginine deiminaεe, type V 10.1
449501 AI652924 Hs.231942 ESTs 10.1
420731 AL042052 Hs.104432 ESTs 10.1
404345 AA730407 Hs.159156 protocadherin U 10.1
400438 AF185611 Target 10.1
438170 AI916685 Hs.194601 ESTs 10.1
432193 AA372264 Hs.273193 hypothetical protein FU10706 10.1
458715 AK000973 Hs.16725 hypothetical protein FU10111 10.1
427766 AA412258 Hs.188817 ESTs 10.1
443426 AF098158 Hs.9329 chromosome 20 open reading frame 1 10.0
403038 Target Exon 10.0
434674 AA831879 Hs.136985 ESTs 10.0
439685 AW956781 Hs.293937 ESTs, Weakly similar to FXD2.HUMAN FORKHEAD BOX PROTE 10.0
439428 AA835825 Hs.190490 ESTs 10.0
403310 Target Exon 9.9
408392 U28831 Hs.44566 KIAA1641 protein 9.9
421849 AW410872 Hs.108894 hypothetical protein FU20411 9.9
433384 AI021992 Hs.124244 ESTs 9.9
443343 BE409809 Hs.301005 purine-rich element binding protein B 9.9
437267 AW511443 Hs.258110 ESTs 9.9
455978 A1310151 Hs.173524 ESTε 9.9
435851 AA700946 Hs.191933 ESTs 9.9
452243 AL355715 Hs.28555 programmed cell death 9 9.9
441703 AW390054 Hs.192843 leucine zipper protein FKSG14 9.9
414001 AI610347 Hε.103812 ESTs, Moderately similar to ALULHUMAN ALU SUBFAMILY 9.9
436669 AA535975 Hs.174308 Homo sapiens, clone IMAGE:3453347, mRNA, partial eds 9.8
421502 AF111856 Hs.105039 solute earner family 34 (sodium phosphate), member 2 9.8
417087 AA193193 Hs.188325 Homo sapiens cDNA FU11484fis, clone HEMBA1001835 9.8
455855 BE147440 gb:RC1-HT0229-080100-015-f09 HT0229 Homo sapiens cDNA 9.8
410390 AA876905 Hs.125286 ESTs 9.8
418526 BE019020 Hs.85838 εolute earner family 16 (monxarboxylic xid transpo 9.8
442660 AW138174 Hs.130651 ESTs 9.8
436186 BE390717 Hs.5074 similar to S. pombe diml 9.8
426773 NM.01555f j Hε.172180 KIAA0440 protein 9.8
413476 U25849 Hs.75393 xid phosphatase 1, soluble 9.7
418347 AA216419 gb:nc16e03.s1 NCI_CGAP_Pr1 Homo εapieπs cDNA clone si 9.7
448752 AA593867 Hs.300842 KIAA1608 protein 9.7
440349 AA884196 Hs.31476 Homo sapiens cDNA FU13872 fis, clone THYRO1001322 9.7
431363 M86528 Hs.266902 neurotrophin 5 (neurotrophin 4/5) 9.7
430752 AA485330 Hs.303278 ESTs 9.7
436523 BE612990 Hε.5212 single-strand selxtive monofuπctional urxil DNA gly 9.7
415740 N80486 Hε.39911 Homo sapiens mRNA for FU00089 protein, partial eds 9.7
411930 F06485 Hs.7740 oxysteral binding protein-like 1 9.7
430832 AI073913 Hs.100686 ESTs, Weakly similar to JE0350 Anterior gradient-2 [H 9.7
452234 AW084176 Hs.223296 ESTs, Weakly similarto I38022 hypothetical protein [ 9.6
409997 A1906055 Hs.57749 synaptic nuclei expreεεed gene 2; KIAA1011 protein 9.6
434957 AF283775 Hs.35380 x 001 protein 9.6
407292 AA876638 gb:nz45e06.ε1 NCI CGAP Pr12 Homo εapiens cDNA clone s 9.6
459109 AW292447 Hs.140821 ESTs 9.6
457892 AA744389 gb:ny51e10.s1 NCI CGAP P 8 Homo sapiens cDNA clone s 9.6
432074 AA525248 Hs.149723 ESTs 9.6
440463 AI733087 Hs.129994 ESTs 9.6
420851 AA281062 Hs.29493 hypothetical protein FLJ20142 9.6
445326 AI220072 Hs.165893 ESTs 9.6
434953 BE049102 Hs.121573 ESTs, Weakly similar to TRHY.HUMAN TRICHOHYALI [Rsap 9.6 420361 N92054 Hs.194718 zinc finger protein 265 9.6
415853 H06016 Hs.100855 ESTs 9.6
429599 AA806106 Hs.123664 ESTs 9.6
417037 BE083936 Hs.80976 antigen identified by moπ∞lonal antibody Ki-67 9.6
449317 AW293413 Hs.132906 19A24 protein 9.6
436588 AA759233 Hε.126506 ESTs 9.6
408261 BE315042 Hs.19210 hypothetical protein MGC11308 9.5
401069 C11000374*:gi|10764778|gb|AAG22817.1|AF302150_1 (AF30 9.5
414065 AW515373 Hs.271249 Homo sapiens cDNA FU13580 fis, clone PLACE1008851 9.5
409902 AI337658 Hs.156351 ESTε 9.5
432258 AW973078 Hε.293039 ESTε 9.5
438581 AW977766 Hs.292133 ESTε, Moderately εimilar to I78885 serine/threoπine-s 9.5
405536 NM_005805:Homo εapieπs 26S proteasome-assxiated padl 9.5
418216 AA662240 Hs.283099 AF15q14 protein 9.5
434573 AW372340 Hs.159717 ESTs 9.5
439354 AF086174 gb:Homo sapienε full length insert cDNA clone ZB94A08 9.5
455410 AW936678 gb:PM2-DT0023-080300-004-a04 DT0023 Homo sapiens cDNA 9.5
400736 Target Exon 9.5
419474 AW968619 Hε.155849 ESTs 9.4
406464 C17000168:gi|7294725|gb|AAF50062.1| (AE003544) CG7547 9.4
407881 AW072003 Hs.40968 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 9.4
427258 AA4O0O91 Hs.39421 ESTs 9.4
404680 Target Exon 9.4
433840 AA129782 Hs.3576 Homo sapiens mRNA full length insert cDNA clone EUROI 9.4
423642 AW452650 Hs.157148 hypothetical protein MGC13204 9.4
457008 AA410446 Hs.112011 ESTs, Weakly εimilar to unknown [H.sapiens] 9.4
435099 AC004770 Hs.4756 flap εtructure-spxific endonuclease 1 9.4
451846 T65840 Hs.11762 ESTs 9.4
419988 W39388 Hs.55336 Homo sapiens, clone MGC17421, mRNA, complete eds 9.4
402967 Target Exon 9.3
455601 AI368680 Hs.816 SRY (sex determining region Y)-box 2 9.3
441075 AA915991 Hs.179214 ets variant gene 3 9.3
451107 AA235108 Hs.17639 Homo sapiens ubiquitin protein ligase (UBE3B) mRNA, p 9.3
404649 Target Exon 9.3
420897 AW139261 Hs.232280 ESTs 9.3
418867 D31771 Hs.89404 mεh (Drasophila) homeo box homolog 2 9.3
420298 AI199510 Hs.267912 ESTε, Weakly similarto ALU7.HUMAN ALU SUBFAMILY SQ S 9.3
449893 T97999 Hs.18214 ESTs, Weakly similarto B34087 hypothetical protein [ 9.3
420101 AW500529 Hs.95180 KIAA0767 protein 9.3
428166 AA423849 Hε.79530 M5-14 protein 9.3
420022 AA256253 Hs.120817 ESTs 9.3
444020 R92962 Hs.35052 ESTs 9.3
454765 AW819629 gb:RC5-ST0293-140200-014-H05 ST0293 Homo sapienε cDNA 9.3
415021 R54409 Hs.301693 Homo εapienε, clone IMAGE:3638994, mRNA, partial cdε 9.3
418506 AA084248 Hs.85339 G protein-coupled rxeptor 39 9.3
415009 C75253 Hs.220950 ESTε 9.3
428845 AL157579 Hs.153610 KIAA0751 gene product 9.3
433348 AA877996 Hs.125376 ESTε, Weakly εimilar to JC5314 CDC28/cdc2-like kinaεe 9.2
417881 AI879117 gb:au54g09.y1 Schneider fetal brain 00004 Homo εapien 9.2
446354 AW449650 Hs.202249 ESTε 9.2
427018 AA397538 Hs.136280 Homo εapiens cDNA: FU22288 fis, clone HRC04157 9.2
434410 AA632644 gb:np87b07.s1 NCI CGAP Thy1 Homo sapiens cDNA clone s 9.2
448072 AI459306 Hs.24908 ESTs 9.2
457322 AI815486 Hs.243901 Homo εapiens cDNA FU20738 fis, clone HEP08257 9.2
424317 AI865032 Hs.26017 ESTs 9.2
433001 AF217513 Hε.279905 clone HQ0310 PRO0310p1 9.2
404112 BE302729 Hs.173162 neighbor of COX4 9.2
433334 AI927208 Hs.231958 matrix metalloproteinase 28 9.1
434960 AW374941 Hs.72545 ESTs 9.1
431658 BE409917 Hs.266935 tRNA selenxyεteine aεsxiated protein 9.1
439158 R60323 Hs.193888 ESTs 9.1
443081 H86858 Hs.132909 ESTs 9.1
429432 AI678059 Hε.202676 synaptonema! complex protein 2 9.1
452706 AW449390 Hs.257150 ESTs, Moderately similar to SUR1.HUMAN SURFEIT LOCUS 9.1
437044 AL035864 Hs.69517 cDNA for differentially expressed C016 gene 9.1
430780 N95102 Hs.334858 hypothetical protein MGC12250 9.1
426793 X89887 Hs.172350 HIR (histone cell cycle regulation defxtive, S. cere 9.1
418379 AA218940 Hs.137516 fidgetin-like 1 9.1
431405 AI470895 Hs.252574 ribosomal protein L10a 9.0
405454 C12000541:gi|5729884|ref|NP_006539.1| IGF-II mRNA-bin 9.0
438362 AA805678 Hs.12326 ESTs 9.0
401940 Target Exon 9.0
424834 AK001432 Hs.153408 Homo sapiens cDNA FU10570 fis, clone NT2RP2003117 9.0
442432 BE093589 Hs.38178 hypothetical protein FLJ23468 9.0
458086 AA021163 Hs.22287 ESTs 9.0
418653 AI734064 Hs.136212 ESTs 9.0
444152 AI125684 Hs.149305 hypothetical protein MGC2603 9.0
437534 AA814471 Hs.291800 ESTs 9.0
435074 AI760944 Hs.116937 ESTs 9.0
406722 H27498 Hs.293441 Homo sapiens SNC73 protein (SNC73) mRNA, complete eds 9.0
442829 AW263123 I Hs.127554 ESTs 9.0
431675 AA699965 Hs.202375 ESTs 9.0
447164 AF026941 Hs.17518 Homo sapiens cig5 mRNA, partial sequence 8.9 420183 W92885 Hε.143408 ESTs 8.9
421133 AA814971 Hs.257634 ESTs 8.9
407605 W03512 Hs.6479 hypothetical protein MGC13272 8.9
441370 AI242433 Hs.270085 ESTs, Weakly similarto ALU1.HUMAN ALU SUBFAMILY J SE 8.9
437966 AW891130 Hs.38173 ESTs
426360 AW290981 Hs.211296 ESTs, Weakly similar to 2109260A B cell growth factor
448111 AA053486 Hs.20315 interferon-induced protein with tetratricopeptide rep
408021 AW137133 Hs.245867 ESTs
429228 AI553633 Hs.337139 ESTs
433914 AF108138 Hs.112160 Homo sapiens DNA helicase homolog (PIF1) mRNA, partia
431184 AW970116 Hs.310616 ESTs
425219 AF207881 Hs.155185 cytosolic ovarian carcinoma antigen 1
439774 AL360257 Hs.213493 Homo sapiens mRNA full length insert cDNA clone EUROI
432573 AA553612 Hs.324696 KIAA1594 protein
450881 W80462 Hs.270521 ESTε, Highly similarto ALU2 HUMAN ALU SUBFAMILY SB S
437835 A1146771 Hs.158008 ESTs
453204 R10799 Hs.191990 ESTs 8.7
412719 AW016610 Hs.129911 ESTs 8.7
408805 H69912 Hs.48269 vxcinia related kinase 1 8.7
428281 AA194554 Hs.183434 ATPase, H transporting, lysosomal (vxuolar proton pu 8.7
422583 AA410506 Hs.27973 KIAA0874 protein 8.7
448148 NM 016578 Hs.20509 HBV pX associated proteiπ-8 8.7
453005 AW055308 Hs.31803 ESTs, Weakly similar to N-WASP [H.sapiens] 8.7
454132 AW131759 Hε.248286 ESTε 8.7
425263 NM.001187 Hε.155419 BCL2-interacting killer (apoptosis-inducing) 8.7
416209 AA236776 Hε.79078 MAD2 (mitotic arrest deficient, yeast, homolog)-like 8.7
441525 AW241867 Hs.127728 ESTs 8.7
459539 A1279186 gb:qm24a04.x1 NCI CGAP.Luδ Homo sapiens cDNA clone 3' 8.7
443148 AI034357 Hs.211194 ESTε, Weakly similar to ALU8.HUMAN ALU SUBFAMILY SX S 8.7
424255 AI192657 Hs.143897 dysferiin, limb girdle muscular dystrophy 2B (autosom 8.7
459435 AA320038 gb:EST22383 Adipose tissue, white II Homo sapiens cDN 8.7
443117 AI248826 Hs.42029 ESTs 8.6
457434 AW628192 Hs.18851 hypothetical protein FU 10875 8.6
442505 AW003775 Hs.198248 UDP-Gal:betaGlcNAc beta 1,4- galxtosyltraπsferase, p 8.6
430901 AA488833 Hs.126711 ESTs, Weakly similar to 138588 reverse transcriptase
439223 AW238299 Hs.250618 UL16 binding protein 2 8.6
417739 Z43995 gb:HSC1QB121 normalized infant brain cDNA Homo sapien 8.6
415961 H10983 Hε.155919 ESTε 8.6
424042 Y10601 Hs.137674 ankyrin-like with tranεmembrane domains 1
451035 AU076785 Hs.430 plastin 1 (I isoform)
447155 AA1OO605 Hs.121557 ESTs, Weakly similar to DP1.HUMAN POLYPOSIS LOCUS PRO 8.6
412668 AA456195 Hε.10056 hypothetical protein FU14621 8.6
458042 AW058464 Hε.6430 protein with polyglutamine repeat; calcium (ca2) home 8.6
456530 AL049437 Hs.100292 Homo sapiens mRNA; cDNA DKFZp586E1120 (from clone DKF 8.6
433345 AI681545 Hs.152982 hypothetical protein FU13117 8.6
445006 W91903 Hs.124814 ESTs i 8.6
453922 AF053306 Hs.36708 budding uninhibited by benzimidazoleε 1 (yeaεt homolo 8.5
455161 BE145900 gb:MR0-HT0208-221299-204-b12 HT0208 Homo εapiens cDNA 8.5
424308 AW975531 Hs.154443 minichromosome maintenance deficient (S. cerevisiae) 8.5
430413 AW842182 Hs.241392 small inducible cytokine A5 (RANTES) 8.5
423494 AW504365 Hε.24143 Wiskott-Aldrich εyndrome protein interacting protein 8.5
415018 U49395 Hs.77807 purinergic receptor P2X, ligand-gated ion channel, 5 8.5
404534 C11001758*:gi|12621132|ref|NP_075243.1| MEGF1 [Rattus 8.5
438451 AI081972 Hs.220261 ESTs 8.5
435176 AA744875 Hs.189413 ESTs 8.5
443245 AI040955 Hs.151973 hypothetical protein FU23511 8.5
443162 T49951 Hs.9029 DKFZP434G032 protein 8.5
457478 T15803 Hε.272458 protein phosphatase 3 (formerly 2B), catalytic subuni 8.5
403839 Target Exon 8.5
434932 BE613162 Hs.284135 hypothetical protein MGC3036 8.5
420991 AW504814 Hs.121004 Homo sapienε mRNA for FU00111 protein, partial eds 8.4
457854 BE547674 Hs.204169 ESTs, Weakly similar to S65657 alpha-1C-adrenergic re 8.4
455994 BE179190 gb:RC0-HT0613-210300-032-f07 HT0613 Homo εapieπs cDNA 8.4
402796 Target Exon 8.4
423426 AW389579 Hs.128434 Homo sapienε ELISC-1 mRNA, partial eds 8.4
429568 AI088691 Hs.208414 Homo sapienε mRNA; cDNA DKFZp564D0472 (from clone DKF 8.4
404110 NM_020245*:Homo εapienε tubby super-family protein (T 8.4
424441 X14850 Hs.147097 H2A histone family, member X 8.4
433155 AL037035 Hs.100426 Homo sapienε cervical cancer metastasis-suppressor 1 (B 8.4
414839 X63692 Hs.77462 DNA (cytosine-5-)-methyltransferase 1 8.4
406867 AA157857 Hs.182265 keratin 19 8.4
418278 AI088489 Hs.83937 hypothetical protein ' 8.4"
458696 AW375333 Hs.199890 ESTs 8.4
456248 AL035786 Hs.82425 xtin related protein 2/3 complex, subunit 5 (16 kD) 8.4
403152 AA576664 Hs.37078 v-crk avian sarcoma virus CT10 oncogene homolog-like 8.4
407649 BE066724 Hε.37427 erythracyte membrane protein band 4.1 (elliptocytosis 8.4
448387 AI874402 Hs.170810 ESTs 8.4
433671 AW138797 Hs.132906 19A24 protein 8.4
425891 AI041717 Hs.132141 ESTs 8.4
447347 AA570056 Hs.122730 ESTs, Moderately similar to Kl AA1215 protein [H.sapie 8.4
439079 AF085937 Hε.38348 ESTs 8.4
458115 BE091587 gb:IL2-BT0731-240400-069-H04 BT0731 Homo sapiens cDNA 8.4
428144 BE269243 Hs.182625 VAMP (vesicle-assxiated membrane protein)-asε∞iated 8.4 424259 AK001776 Hs 143954 hypothetical protein FU10914 83
443056 AI457996 Hs 132578 ESTs 83
410391 H17881 Hs 15043 Homo sapiens clone FLB5227 PR01367 mRNA, complete eds 83
407989 AW135208 Hs 256092 ESTs 83
410536 N39533 gb yv27d04 s1 Soares fetal liver spleen 1 NFLS Homo sa 83
452273 AI870685 Hs 231022 ESTs 83
454297 AI223335 Hs 50651 Janus kinase 1 (a protein tyrosine kinase) 83
453718 AL119317 Hs 120360 phospholipase A2, group VI (cytosolic, calcium indepe 83
401654 NM 007242 Homo sapiens DEAD/H (Asp-Glu Ala-Aεp/His) b 83
432891 AF161483 Hs 279761 HSPC134 protein 83
419923 AW081455 Hs 120219 ESTs 82
433627 AF078866 Hs 284296 Homo sapienε cDNA FLJ22993 fis, clone KAT11914 82
435452 AA831004 Hs 124874 ESTs 82
418683 U90908 Hs 87241 hypothetical protein from clones 23549 and 23762 82
440065 W03476 Hε 266331 hypothetical protein MGC4595 82
439752 T78968 Hε 14411 ESTs 82
447983 AW612726 Hε 282113 ESTs, Weakly similar to I38022 hypothetical protein [ 82
441966 AA568689 Hs 16131 hypothetical protein FLJ12876 82
408182 AA047854 gb zf49g04 r1 Soares retina N2b4HR Homo sapiens cDNA 82
432180 Y18418 Hs 272822 RuvB (E coli homolog) like 1 82
436005 BE551650 Hs 158126 Homo sapiens cDNA FLJ13350 fis, clone OVARC1002143 82
414962 AF273304 Hs 235376 XPMC2 protein 82
444476 AF020038 Hs 11223 isocitrate dehydrogenase 1 (NADP), soluble 82
408175 W29089 Hs 19066 hypothetical protein DKFZp66702416 82
413940 AI633205 Hs 159914 ESTs, Weakly similar to I78885 seπne/threonme-εpxi 82
437277 AA748016 Hs 123370 ESTε 82
431445 AA505135 Hs 44037 ESTε 81
418927 BE349635 Hs 190284 ESTε 8 1
452446 AA086123 Hs 297856 ESTs 8 1
445380 AI222019 Hs 144838 ESTs 81
421174 AW969058 Hs 291974 ESTs, Moderately similar to A46010 X linked retinopat 8 1
444374 AA009841 Hs 11039 hypothetical protein MGC2722 81
417247 N58024 gb yv63c01 s1 Soares fetal liver spleen 1NFLS Homo sa 8 1
438335 AI498421 Hs 243168 ESTs 81
445235 AI564022 Hs 138207 ESTs 81
422585 NM 016186 Hs 118620 protein Z-dependent protease inhibitor precursor 81
442522 AI087038 Hs 146592 ESTs, Weakly similarto ALU7.HUMAN ALU SUBFAMILY SQ S 81
430684 AI808979 Hs 293193 ESTs 81
446442 BE221533 Hε 257858 ESTs 8 1
441410 AA932689 Hs 233304 ESTs, Weakly similar to I38022 hypothetical protein [ 80
419485 AA489023 Hs 99807 ESTs, Weakly similarto unnamed protein product [H sa 80
449539 W80363 Hs 58446 ESTs 80
406663 U24683 Hs 302063 immunoglobulin heavy constant mu 80
423767 H18283 Hs 132753 F-box only protein 2 80
450937 R49131 Hs 26267 ATP-dependant interferon response protein 1 80
430977 AA490069 Hs 306676 Homo sapiens cDNA FU 14302 fis, clone PLACE2000003 80
455677 BE066061 Hs 8867 cysteine-nch, aπgiogemc inducer, 61 80
436706 AA725808 Hs 194609 ESTs 80
459407 N92114 gb za22h11 r1 Soares fetal liver spleen 1 NFLS Homo sa 80
444132 AK000452 Hs 10340 hypothetical protein FU20445 80
437149 AI686651 Hs 202234 ESTs, Weakly similar to ALU4.HUMAN ALU SUBFAMILY SB2 80
418499 AI627392 Hs 302023 hypothetical protein FKSG25 80
411298 AW835858 gb PM0-LT0017-031299-001 -h07 LT0017 Homo sapiens cDNA 80
432571 AF151054 Hs 278429 hepatocellularcarαnoma-aεsxiated antigen 59 80
416295 AI064824 Hs 193385 ESTε 80
427485 AF039652 Hs 178655 πbonuclease H1 80
409857 AW501908 gb UI-HF-BROp-ajp-c-12-O-Ul rl NIH MGC.52 Homo sapien 79
433854 AA610649 Hs 333239 ESTs 79
458080 BE142728 gb MR0-HT0157-021299-004-08 HT0157 Homo sapiens cDNA 79
423573 AA328504 gb EST31993 Embryo, 12 week 1 Homo sapiens cDNA 5' en 79
404495 C8001441* gι|8923061|ref|NP_0601141| hypothetical pr 79
443135 AI376331 Hs 156103 ESTs 79
448939 BE267795 Hs 22595 hypothetical protein FU 10637 79
413283 R78669 Hs 23756 hypothetical protein similar to swine xylneuraminate 79
443987 AW163123 Hs 10071 seven transmembrane protein TM7SF3 79
434197 AA627223 gb nq63b04 s1 NCI.CGAP.Ovδ Homo sapiens cDNA clone si 79
436882 AW016722 Hs 194976 SH2 domain-containing phosphatase anchor protein 1 79
434502 AW974915 Hs 116550 ESTs 79
435507 AI143579 Hs 26510 vxuolar protein sorting 33B (yeast homolog) 79
444896 AI201480 Hs 144856 ESTs 79
419320 H96666 Hs 6137 ESTs 79
446269 AW263155 Hs 14559 hypothetical protein FU10540 79
425569 AA359597 Hs 301701 Homo sapienε cDNA FU12073 fis, clone HEMBB1002387 79
445209 AW294230 Hs 80988 collagen, type VI, alpha 3 79
449193 AI637997 Hs 195653 ESTs 79
447397 BE247676 Hs 18442 E-1 enzyme 79
455037 BE144549 gb MR0-HT0167 081199-001-a02 HT0167 Homo sapiens cDNA 79
453367 AW732847 Hs 70573 PKCI-1-related HIT protein 78
439317 AF086127 Hs 50600 ESTs, Weakly similar to T47156 hypothetical protein D 78
424006 AF054815 Hs 137548 CD84 antigen (leuk∞yte antigen) 78
406562 NM.004520* Homo sapiens kinesm heavy chain member 2 78
435192 AK000739 Hs 4835 eukaryotic translation initiation fxtor 3, subunit 8 78
413500 BE144914 gb CM3-HT0183-181099-023-b05 HT0183 Homo sapiens cDNA 78 436216 AA380887 Hs 5085 dolichyl phosphate mannosyltransferase polypeptide 1 78
418623 AW194757 Hs 266804 ESTs 78
447197 R36075 gb yh88b01 s1 Soares plxenta Nb2HP Homo sapienε cDNA 78
430146 AW815330 gb QV0-ST0215-O6O100-083-aO9 ST0215 Homo sapiens cDNA 78
441841 AA971819 Hs 176083 ESTs 78
457677 AA628880 Hs 158701 ESTs 78
421090 BE301870 Hs 101813 solute camerfamily 9 (sodium/hydrogen exchanger), 78
436481 AA379597 Hs 5199 HSPC150 protein similar to ubiquitin-conjugatiπg enzy 78
434407 AW815333 gb QVO-ST0215-060100-083-g01 ST0215 Homo sapiens cDNA 78
406410 05000010' gι|10440464|dbj|BAB15765 1| (AK024475) FU0 78
453579 AI204463 Hs 61857 ESTs 78
427584 BE410293 Hs 179718 v-myb avian myeloblastosis viral oncogene homolog lik 77
452139 AA099969 Hε 16331 Homo sapiens cDNA FU21482 fis, clone COL05135 77
405510 ENSP00000233779* Hypothetical 680 kDa protein 77
440777 AA994020 Hs 128553 ESTs 77
446424 AW134529 Hs 244647 ESTs 77
448004 AW451477 Hs 257456 ESTs 77
430610 AI821465 Hs 188810 ESTs, Weakly similar to ALU6.HUMAN ALU SUBFAMILY SP S 77
427080 AW068287 Hs 173466 ras related C3 botul um toxin substrate 2 (rho famil 77
451693 BE220445 Hs 279635 ESTs 77
417558 AF045229 Hs 82280 regulator of G-protein signalling 10 77
420344 BE463721 Hs 97101 putative G protein-coupled rxeptor 77
427735 AA916785 Hs 180610 splicing fxtor proline/glutamine πch (polypyπmidin 77
425423 NM.005897 Hs 157180 intracistemal A particle-promoted polypeptide 77
450663 H43540 Hs 25292 πbonucleaεe HI, large subunit 77
432585 AA705591 Hs 190209 ESTs 77
402682 Target Exon 77
400247 Eos Control 77
421116 T19132 Hs 101850 retinol-binding protein 1, cellular 77
426761 A1015709 Hs 172089 Homo sapiens mRNA, cDNA DKFZp586l2022 (from clone DKF 77
405514 ENSP000OO241O75 TRRAP PROTEIN 77
412406 AW948172 gb RCO-MT0013-280300-021-b06 MT0013 Homo sapiens cDNA 77
440226 AA873387 Hε 207330 ESTε 77
435625 H50654 Hs 113999 ESTs 77
418529 AW005695 Hs 250897 TRK-fused gene 76
407758 D50915 Hs 38365 KIAA0125 gene product 76
447276 AL049795 Hs 17987 hypothetical protein MGC1203 76
449938 AW970612 Hs 172635 Homo sapiens cDNA FU21367 fis, clone COL03051 76
422893 X98411 Hs 121555 myosin IF 76
451593 AF151879 Hs 26706 CGI-121 protein 76
424148 BE242274 Hε 1741 integnn, beta 7 76
447519 U46258 Hs 339665 ESTs 76
409361 NM 005982 Hs 54416 sine xulis homeobox (Drasophila) homolog 1 76
436279 AW900372 Hs 180793 ESTs, Weakly similar to S65657 alpha-1C-adrenergιc re 76
426523 S68616 Hs 170222 solute earner family 9 (sodium/hydrogen exchanger), 76
456926 AB018284 Hs 158688 KIAA0741 gene product 76
416294 D86980 Hs 79170 KIAA0227 protein 76
409206 AW364844 gb QV3-DT0044-221299-045-C03 DT0044 Homo εapienε cDNA 76
417086 AA194446 Hs 73451 ESTs, Weakly similarto S55024 nebulm, εkeletal muse 76
418181 U37012 Hs 83727 cleavage and polyadenylation spxific fxtor 1, 160kD 75
436910 AA926944 gb om68g01 s1 NCI.CGAP.GC4 Homo εapiens cDNA clone 3' 75
401008 Target Exon 75
413245 BE244334 Hs 75249 ADP-πbosylation factor-like 6 interacting pratem 75
446820 AW295037 Hs 254986 ESTs 75
439279 A1039473 Hs 130636 ESTs 75
426116 AA868729 Hs 144694 ESTs 75
410098 BE326839 Hs 17433 hypothetical protein FU20967 75
422326 AI114875 Hs 78592 eukaryotic translation initiation fxtor 2B, εubumt 75
435513 AW404075 Hs 42785 DC11 protein 75
421629 N80121 Hs 4983 ESTs 74
434663 AA641972 Hs 130058 ESTs 74
452461 N78223 Hs 108106 transcnption fxtor 74
418811 AK001407 Hs 88663 hypothetical protein FU10545 74
405417 CX001144* gι|7242973|dbj|BAA92547 1| (AB037730) KIAA1 74
414076 AA467736 gb nc74e05 s1 NCI_CGAP_Pr2 Homo sapiens cDNA clone, m 74
435014 BE560898 Hs 10026 mitxhondπal πbosomal protein L17 74
449610 AI242042 Hs 14044 ESTs 74
403397 Target Exon 74
436873 N23874 Hs 50477 RAB27A, member RAS oncogene family 74
451386 AB029006 Hs 26334 spastic paraplegia 4 (autosomal dominant, spastin) 74
404914 NM.O04O46* Homo sapiens ATP synthase, H+ transporting 74
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet xtivatmg fxt 74
432820 AI554057 Hs 152477 ESTs 74
418978 T85295 Hs 268606 ESTs 74
446636 AC002563 Hs 15767 citron (rho-interxting, seππe/threonine kinase 21) 74
454639 AW811633 gb RC2-ST0158-091099-011-d05 ST0158 Homo sapiens cDNA 74
434522 AF189259 Hs 283081 gamma-aminobutyπc xid (GABA) rxeptor, theta 74
458236 AW297043 Hs 255604 ESTs, Weakly similar to A47234 homeobox pratem H6 [H 74
441043 AA913422 Hs 192104 ESTs 74
422838 AA524065 Hs 93670 Homo sapiens cDNA FU22664 fis, clone HSI08202 73
455096 AW855718 gb RC1-CT0279-070100-021-a06 CT0279 Homo sapiens cDNA 73
442307 AW027690 Hs 90037 ESTs 73
425453 AW374284 Hs 297215 Homo sapiens chromosome 19, cosmid R26894 73 455327 AW896238 Hs 334805 Homo sapiens cDNA FU14604 fis, clone NT2RP1000363, m 73
420982 AW576160 Hε 100729 KIAA0692 protein 73
424563 AA446932 Hs 151428 ret finger protein 2 73
417125 AW181998 Hs 81248 CUG triplet repeat RNA-bindmg protein 1 73
453902 BE502341 Hs 3402 ESTε 73
446842 AI343510 Hs 176992 ESTs 73
454128 AL031259 Hs 41639 programmed cell death 2 73
427011 BE302729 Hs 173162 neighbor of COX4 73
450872 AI742594 gb g55h05 x1 Soares NSF F8 9W OT.PA.P_S1 Homo sapien 73
451512 AI800236 Hs 207080 ESTs 73
406708 AI282759 gb qt84a01 x1 NCI.CGAP.Co14 Homo sapiens cDNA clone 1 73
432576 AW157424 Hs 165954 ESTs, Weakly similarto 138022 hypothetical protein [ 73
459304 AW005809 Hs 281076 ESTε, Weakly similar to CHD4.HUMAN CHROMODOMAIN HELIC 73
401375 NM 020999* Homo sapiens neurogeniπ 3 (NEUROG3), mRNA 73
413258 BE075114 gb PM1-BT0585-110200-003-C11 BT0585 Homo εapienε cDNA 73
406016 Target Exon 73
421506 BE302796 Hs 105097 thymidine kinase 1, soluble 73
422742 AA316117 Hs 337128 ESTs 73
440031 BE045970 Hs 244746 ESTs 73
429389 AA454779 Hs 201441 Homo sapiens cDNA FLJ11079 fis, clone PLACE1005111 73
449656 AA002008 Hs 188633 ESTs 73
444310 AI140432 Hs 175936 ESTs 73
459274 AA382590 Hs 170980 KIAA0948 protein 73
425404 BE048060 Hs 133494 Homo sapiens clone TCCCIA00164 mRNA sequence 73
431150 T63857 gb yc16e01 s1 Stratagene lung (937210) Homo sapiens c 73
443217 NM 001545 Hs 9078 immature colon carcinoma transcπpt 1 72
413405 AW022253 Hs 215976 ESTs 72
447653 BE327277 Hε 161145 ESTs 72
414704 NM 014757 Hs 76986 mastermind (Droεophila) homolog of 72
424046 AF027866 Hs 138202 seπne (or cysteine) proteinase inhibitor, clade B (o 72
409188 AW363284 Hs 32553 ESTs 72
453493 AL039478 Hs 304447 ESTs Weakly similarto ALU1.HUMAN ALU SUBFAMILY J SE 72
456111 AK000150 Hs 78185 MAX like bHLHZIP protein 72
400297 AI127076 Hs 334473 hypothetical protein DKFZp56401278 72
446364 AB006624 Hs 14912 KIAA0286 protein 72
432215 AU076609 Hs 2934 πbonudeotide reductase M1 polypeptide 72
436943 AA773838 Hs 5353 caspase 10, apoptosis-related cysteine protease 72
446336 AW815036 Hs 151251 ESTs 72
418469 U34879 Hs 85279 hydraxyεteroid (17-beta) dehydrogenaεe 1 72
414907 X90725 Hs 77597 polo (Droεophia) like kinase 72
429065 AI753247 Hs 29643 Homo sapiens cDNA FU13103 fis, clone NT2RP3002304 72
424568 AF005418 Hs 150595 cytochrome P450, subfamily XXVIA, polypeptide 1 72
416450 AA180467 gb zp14g08 s1 Stratagene fetal retina 937202 Homo εap 72
449714 AB033015 Hs 23941 KIAA1189 protein 72
455447 AW947507 gb RCO-MT0002-140300-011-a12 MT0002 Homo εapiens cDNA 72
437154 AI023133 Hs 10739 ESTs 72
423059 AW378445 Hs 123080 Homo sapiens unknown protein mRNA, partial eds 72
419092 J05581 Hs 89603 mucin 1, transmembrane 72
426736 AA431615 Hs 130722 ESTs 72
417748 Z43011 Hs 21169 ESTs 72
434748 AI862604 Hs 211884 ESTs, Weakly similar to ALU1.HUMAN ALU SUBFAMILY J SE 72
438929 AW195515 Hs 253177 ESTs 72
452061 AI074259 Hs 469 succinate dehydrogenase complex, subunit A, tlavoprot 71
446416 AV658299 Hs 163959 ESTs 71
415023 AA932146 Hs 133494 Homo sapiens clone TCCCIA00164 mRNA sequence 71
434766 AA742222 Hs 120634 ESTs 71
432566 AW439330 Hs 256888 ESTs, Weakly similar to 2109260A B cell growth fxtor 71
420252 AW270404 Hε 193161 ESTs 71
435403 AA779987 Hs 269658 ESTs 71
430151 AW968203 gb EST380398 MAGE resequences, MAGJ Homo sapiens cDNA 71
427908 AA417272 Hs 24122 ESTs 71
417758 U27699 Hs 82535 εolute camerfamily 6 (neurotransmitter transporter 71
400098 Eos Control 71
412647 AW975090 gb EST387196 MAGE resequences, MAGN Homo sapiens cDNA 71
437234 AI472213 Hs 247711 hypothetical protein FU20557 71
453366 AW958751 Hs 28921 zinc finger protein 71
425803 AI825204 Hs 211408 ESTs 71
447383 N24231 gb yx22a11 Soares melan∞yte 2NbHM Homo sapiens cD 71
423864 BE275607 Hs 1708 chaperonin containing TCP1, subunit 3 (gamma) 71
450799 AW407504 gb UI-HF-BMO-adk-g-12-O-UI NIH.MGC.38 Homo sapienε 71
409592 BE280951 Hs 55058 EH-domain containing 4 71
453945 NM.005171 Hs 36908 xtivating transcnption fxtor 1 71
425196 AL037915 Hs 155097 carbonic anhydrase II 70
439778 AL109729 Hs 99364 putative transmembrane protein 70
417662 R07478 Hs 268845 ESTs 70
438087 AI863770 Hs 190422 ESTs 70
452724 R84810 Hs 30464 cyclin E2 70
448633 AA311426 Hs 21635 tubulin, gamma 1 70
433154 AA578526 Hs 160984 ESTs 70
440094 AI651558 Hs 270372 ESTs, Weakly similarto ALULHUMAN ALU SUBFAMILY J SE 70
409253 H91200 Hs 52002 CD5 antigen like (scavenger rxeptor cysteine πch fa 70
431270 BE046609 gb hn41e11 x1 NCI CGAP.RDF2 Homo sapienε cDNA clone 3 70
407629 AA649242 Hs 62632 ESTε 70 408286 AL117452 Hs.44155 DKFZP586G1517 protein 7.0
445439 BE243084 Hs.12719 regulator of nonsense transcripts 1 7.0
427106 AA398193 Hs.97584 ESTs 7.0
408623 AW811978 Hs.254037 ESTs 7.0
426561 AA381437 gb:EST94514 Activated T-cells I Homo sapiens cD A 5' 7.0
408492 AA555217 Hs.183684 eukaryotic translation initiation fxtor 4 gamma, 2 7.0
428894 AA437066 Hs.271736 ESTs 7.0
419102 AA234098 Hs.42424 ESTs, Weakly similar to 2004399A chromosomal protein 7.0
429067 AA446019 Hs.104967 ESTs 7.0
422684 BE561617 Hs.119192 H2A histone family, member Z 7.0
424701 NM.005923 Hs.151988 mitogen-xtivated protein kinase kinase kinase 5 7.0
412513 AA322599 Hs.5163 ESTε, Weakly εimilar to AF151840 1 CGI-82 protein [H. 7.0
443599 A1079559 Hs.134125 ESTs 7.0
400715 ENSP00000237081 *:KI AA1217 PROTEIN (FRAGMENT). 7.0
446514 AW449233 Hs.150847 ESTs 7.0
413992 W26276 Hs.136075 RNA, U2 small nuclear 7.0
402442 Target Exon 7.0
419497 NM.006410 Hε.90753 Tat-interacting protein (30kD) 7.0
439575 W79259 gb:zd75c06.r1 Soares_fetal_heart_NbHH19W Homo sapiens 7.0
407027 U63312 gb:Human cosmid LL12NC01-242E1, ETV6 gene, exons 1B a 7.0
Table 15B Pkey: Unique Eos probeεet identifier number
CAT number Gene cluster number Accession: Genbank xcession numbers
Pkey CAT Number Acceεεioπs
408182 104479 1 AA047854 AA057506 AA053841 409113 110079.2 AA074897 AA113914 AA064871 AA079329 AA071309 AA084710 AA129030 AA075042 AA074794 AA071453 AA078803 AA148628 AA122204
M074159 AA126185 AA079117AA127089 AA070912AA079280AA131372AA078833AA071087 AA076131 AA071047 AA079401 AA083070
AA102076 AA115163 AA074198 AA134725 AA113889 AA121103 AA075041 AA065148 AA071310 AA101144 AA079659 AA078931 AA079209
AA070928 AA068994 AA069817 AA076187 AA069053 AA131489 AA071308 AA063317 AA070156 AA071430 AA076056 AA075684 AA070053
AA126283 AA126078 AA075895 AA079208 AA074583 AA071086 AA079623 AA070627 AA078802 AA076622 AA065051 AA079143 AA071110
AA079434 AA148748 AA079230 AA085188 AA074485 AA070580 AA076151 AA083166 AA085118 AA079450 AA085044 AA120938 AA079200
AA100188 AA081472 AA122355 AA129031 AA085362 AA069220 AA070940 AA075968 AA074563 AA084027 AA115929
409206 1108161 1 AW364844 AW364847 AW937534 AW937593 AW937659
409857 1156298 1 AW501908 AW502959 AW502540
410146 1178974 1 AW592655 R05927 R06916
410536 1207322 1 N39533 AW753094 AW753093
411298 1237955.1 AW835858 AW835836 AW835823 AW835834 AW835831 AW835832 AW835843 AW835816 AW835833 AW835815 AW835849 AW835835
AW835848 AW835851 AW835852 AW835862 AW835855 AW835825 AW835847 AW835838
412406 1293055.1 AW948172 AW848178 AW948169 AW948176 AW948191 AW948192 AW948186 AW948184 AW948187 AW948188 AW948189 AW948181
AW948177 AW948171 AW948183 AW948173
412647 1317604 1 AW975090 N44182
413258 1355998 1 BE075114 BE075283 BE075118
413314 1360034 1 BE081585 BE081717 BE081863 BE081794 BE081659
413500 1373933 1 BE144914 BE394989
414076 141490 1 AA467736 AA135210 AW968166 AA467804
416450 159551 1 AA180467 AA449184 AA464831 AA505048
417247 1660859 1 N58024 T58194 T11693 N64222 T05848
417739 1696198 1 Z43995 R12357 R34740
417881 170544 1 AI879117AW161351 Z45755 BE003661 AA206949 AA476541
418347 174149 1 AA216419 F03238 AA229517
422429 216469 1 AA310527 AW962295 Z44865 H06641
423573 229714 1 AA328504 AA327783 AW962370
426561 269158 1 AA381437 AA628833 AW407275
428294 289365 1 AA425488AA496895 F23221
430146 313562 1 AW815330 AW968170 AI732687 AI732725 AA468343 AA467817 AW063961
430151 313668 1 AW968203 AI732757 AA470353 AA468025 AA468479 AI734151
430709 322338 1 R34356 AW969880 AA484613
430848 324621 1 AW021726 AA487752 AA488085
431150 328626 1 T63857 AW971220 AA493469 T63699
431270 330676 1 BE046609 BE046118 AA501504
432363 345469 1 AA534489 AW970240 AW970323
434197 381655.1 AA627223 AA643443 AA650619 AA643463 AA643453 AA643439 AA643438 AW802964 AW821595 AW821594 AA643431 AA643432
AW827513
434407 385744 1 AW815333 AW815409 AA632563
434410 385798 1 AA632644 AA635376 AA664188
436910 429182.1 AA926944 AA767974 AA737237
437056 432262 1 AI147061 AA743380 AA765223 AW976398 AI803927
439354 47146 ϊ AF086174W31796W04694
439575 47400, 1 W79259 AF086396 W73927
444314 600667 1 AI140497 AW749625 AW749626 AW749644
447197 711623 1 R36075 AI366546 R36167
447383 71990 1 N24231 BE617S64 N36313
450799 847242.1 AW407504W31274AI738877
450872 849959 1 AI742594AI761397 R31198 AI819332 R31257
454355 1130264 1 AW812535 AW812536 AW390307
454639 1227728 1 AW811633AW811652AW811898
454765 1233905 1 AW819629AW854320 455037 1249783 1 BE144549 AW851677 AW851643 AW851711 AW851719 455096 1253078.1 AW855718 AW855740 AW855748 455161 1256167.1 BE145900 AW859906 BE145895 BE145831 BE145914 BE145820 BE145817 BE145890 BE145908 455410 1288380.1 AW936678 AW936637 AW936S82 AW936685 AW936817 AW936811 AW936762 AW936653 AW936815 AW936812 AW936683 AW936822
AW936823 AW936821 AW936732 AW936730 AW936781
455447 1292444.1 AW947507 AW947509 AW947791 BE008335 455855 1375834.1 BE147440 BE147708 BE147563 BE147456 455994 1398737 1 BE179190 BE179206 BE179182 BE179185 BE179186 BE179194 457892 432926.Ϊ AA744389 AA744270 AA744284 AA744299 AA745380 AA744337 AA846905 AA847698 458080 471050.1 BE142728 AA834047 AW937124 458115 47705.29 BE091587 BE091730 BE091577 BE091655 BE091729 BE091640 BE091578 BE091727 BE091803 BE091660 BE091721 BE088255 BE076582
AW992312 BE008791 BE082385 BE083504 BE083466 AW997967 AW997991 BE166595 AW843686 AW844334 BE079091 AW603391 BE081427 BE079514 BE184580 BE009962 BE008722 AW579912AW860561 AW890184 AW795276 AW860410 AW860411 AW610330 AW860564 AW860578 AW862519 BE073924 BE008687 BE073857 BE073921 AW274106 BE011060 AW268120 AI335067 AW793748 AW997736 BE080117 AW867987 AI547161 AW844767 AW393596 AW579444 BE083334 AI547158 AW799863 AA585179 AW992792 AW882215 BE011913 AW997894 AI547159 AW992772 AW581178 AA092247 AW843916 BE079190 AW878478 BE083648 BE066454 AI469937 AW393594 AW579899 AW939276 BE173265 AW878631 AW878638 AW992802 BE079913 AA633638 AW369008 BE076590 AW843456 AW992791 BE173247 AW843921 AW843333 AW878334 BE090235 BE078240 BE066325AW603276 BE169310AW817299 BE091641 BE000160AW898164AW994624AW999391 AW862797AW899438 AW750667 AW939685 AW940017 A1200402 BE167391 AW939318 AW799837 AW939953 AW939681 BE078188 AA449059 BE076595 AW297451 BE076544 AW803372 BE081223 AW939237 BE084239 AI174202 BE077804 BE078028 AA512912 AI124808 AI147524 AI884882 AW939962 AW939254 BE171687 AW998400 AW998348 AW998353 AW998288 AW998303 AW998302 AW998299 AA502748 BE077882 AW998295 BE090238 AW604665 AI423051 BE093093 AW579913 AW606384 BE006143 BE170415 AW998054 BE084608 AW992779 BE088111 AW610555 AW844153 AW939423 BE085404 AW579905 BE080994 AW468482 AW876865 BE091581 BE080940 AI811189 AW868088 AW893127 BE080064 BE184254 AW998350 AW884228 AW992315 AW992364 BE091569 AW750680 BE066386 AA578227 BE091735 AW938830 BE078710 BE087253 BE084182 AW800859 AW801017 AW581371 BE088300 AW995341 BE090233 AW663786 BE091739 BE080113 AW578162 AW799799 AW992366 AW994673 BE185170 AW792778 AW663225 BE075590 BE080111 AA682934 BE090227 AI475441 BE085684 BE090223 AW581366 BE010705 AW898740 BE088170AW992375 BE077833 BE083557 BE010688 AW998450AW803434 BE083280 AW892655 AA506666 BE088288 BE005859 BE173856 BE001319 AA610814 BE011965 BE005855 BE005869 AA973929 BE185729 AW884298 BE185743 BE001342 BE005876 AI002988 AW799056 BE085411 AW841264 AW603110 BE006134 BE006139 BE006148 BE006147 BE006155 AA578273 BE008706 BE185440 AW946428 AA501940 AW603114 BE085757 AI460195 AA491145 AA772914 AA632730 AA508388 BE080196 BE185442 BE093446 AW946433 BE080119 BE001352 AW839003 BE006145 BE085405 BE008680 BE081428 AW581373 AW607246 BE094328 BE001336 AW868170 BE074119 AW884149 BE091734 BE008744 AI540867 BE185806 BE080193 BE185858 AA476398 BE081O40 BE074724 BE085426 BE074725 AW998297 AW867606 BE185798 AW898734 BE076369 BE081672 BE088178 AA610264 BE088118 AA284217 AW578085 BE074518 BE001359 BE001328 AW820227 AW868196 AW868190 AW904548 BE008526 BE012037 BE079061 BE005870 AW867804 AW878433 BE008751 BE005875 BE008748 BE093440 BE183050 AA506676 BE001329 BE008803 BE080123 BE008041 AW994688 AW994675 AW994760 AW994691 AW994681 BE080189 BE080112 AW868173 AI768000 AW883094 AW868179 BE080201 AW665449 BE067473 BE008746 BE184053 BE076437 BE076376 BE076402 AA4803958E082436 BE184134 BE185224 BE085428 BE008682 AW868181 AW998358 AW866102 BE083507 BE077974 BE008835 BE093439 BE076108 AI416987 BE008788 BE069909 BE093441 BE185502 BE183053 AW750669 BE011812 BE008672 BE081684 BE093445 AW868184 BE081839 BE008797 AW842067 BE008678 BE008670 BE551820 AW838974 BE081637 BE046696 BE008673 BE010328 BE083250 BE089614 BE082052 BE081424 BE001678 AW581368 AA503194 AW883721 AW883522 BE085564 AW868717 BE171078 BE078249 BE078194 AA565255 BE083486 AW842081 AW842080 AW868204 BE008717 AA484369 AI831719 AW997365 BE079327 AA503956 BE091999 AW793852 BE080251 BE078086 BE092515 BE170364 AW866193 AW067958 BE008042 BE008761 BE081681 BE081671 AW867400 BE082003 BE082253 BE081439 BE081486 BE081692 AW606020 AA501778 AW996417 BE045756 BE088394 AA491068 AW893099 AW578695 BE150440 BE006150 BE084684 AW992796 BE086891 AW866792 AW753605 BE082045 BE081106 BE008373 BE075399 AW996628 AW578707 BE084309 AW753604 BE185916 AW842220 BE185222 BE006152 BE008795 AW578706 BE080256 BE183984 AI934532 AA449648 AW578699 BE150514 AW883580 AA493568 BE085748 AW753601 BE150562 AW882677 BE091797 AW899123 BE081679 BE080121 AW606787 AW603410 BE001317 AW905799 BE150513 BE092206 AW996343 BE086922 BE008806 AW844759 AW606009 BE150487 AW750728 BE150491 BE150515 AW606010 BE150508 BE008718 AW578702 BE150509 AA436751 AW883918 BE183883 AW753607 BE008669 BE150446 AA533458 BE079219 AW838884 AW063806 AW063837 AW878479 BE078815 BE008802 AW992789 BE007925 AW8022O4 BE011825 BE092130 BE184059 BE079087 BE150568 BE185497 BE078808 AW883761 AW842295 BE161523 AA484796 AA480390 AW994667 BE073205 AW607316 BE083201 AW802265 AW578700 BE078715 AW860403 AW897456 AW996558 AW890602 AW860413 AA425412 BE008364 BE150438 AW602606 A1435236 AA574285 AI823745 AA501773 A1002987 AW832749 BE185491 AW996489 BE001442 AW946425 BE001586 AI524864 BE085556 AW867549 AW604038 BE079832 AI752160 AW999398 AW883904 AW882376 AW467098 BE080116 AW883984 AW883995 AA424095 BE074091 AW996348 AW860625 AW860633 AW946513 BE083485 AW860412 AW602207 BE075407 AW838972 AW607023 AW602201 AW799772 AW862452 AW862451 BE505041 BE161537 AW602206 AW860404 AW860555 BE007843 AW860632 AW862457 AW998019 AW860405 BE092062 AW603921 BE183386 AW868194 BE075664 BE078184 AI541202 AI204949"BE092451 AW603111 AA484587 AA484402 AW998675 AW896064 BE069923 AW867965 BE069919 BE092069 AA807842 AW605500 AW605501 BE085409 AA506738 BE080080 AW749523 AA493134 AW370137 AA491844 AA504425 AW605473 BE092456 BE010682 AW602608 BE079093 AA484911 BE010942 AI205087 AW794933 BE081848 BE011792 AW799897 BE174618 AW838848 AW821741 AW842724 BE008764 BE183962 AA501765 BE092513 BE183342 AW799806 AA442935 BE092268 AA580022 AW843219 BE093308 BE092275 BE087111 BE183392 AW842678 BE185597 BE183895 BE185278 BE082343 AW946219 BE079199 BE092272 AA586687 AW946109 AW946175 AW946184 BE008365 BE078172 BE085673 BE076240 BE083194 BE010604 BE079196 AW878636 AW799803 BE001348 BE077883 BE081835 AW992309 BE081012 BE078106 AW881899 BE008407 BE008410 AW842670 AW603738 BE088661 AA484571 A1799184 BE174545 BE001405 AA436967 AW995884 AW995785 AW896598 AW883999 BE075967 AA503938 BE092281 BE092279 BE087460 BE087569 BE081542 AI375386 AW843886 BE080115 BE171517 BE079898 AW882382 BE001450 BE076430 AW579377 BE008412 BE008790 BE182296 BE182297 BE078805 AW899132 BE078810 BE185867 BE087790 AA484928 AW578985 BE008400 BE074080 AW605101 BE076110 AW799904 A1205094 BE008370 BE182345 BE182373 BE008401 AA984441 BE182362 BE182372 BE008414 BE078186 BE009165 BE010266 BE009162 BE009167 BE011006 BE073335 BE182370 AW750556 BE182347 BE011000 AA484576 BE092982 BE183897 BE092973 AA573037 AW882317 BE081832 AA478471 AA551613 BE182366 AW838886 AW026827 BE008413AW896605AA503558AA776622 BE084825AA502971 BE081842BE010628AW802218AI888924AW867986AW881775BE079220 A1241060AW802041 AW802005 BE011244 BE087051 AA984758 AA452997AW992786 AW797500 BE077829 BE008402AW881760 BE093516 AW802084AW369007 BE185123 BE087775AW801018 BE093443AW867978AW843271 BE173850AW997859 BE010620 AW992516AW843908 BE083200 BE164675 BE07434O AW880289 BE075433 BE008456 AW946438 BE066570 BE093547 AA508107 AW867992 BE076239 BE183881 AW817422 BE087717AW899147 BE010608AW992295AA436737 BE075412 BE093011 AW581656 BE089529 BE008756 BE150494AW903020 AW883102 BE076370 BE000625 BE166095 AW867979 BE182159 AW577501 AW577488 AW577491 BE010637 BE069910 BE093295 BE005243 AI620783 AW992550 AW890590 AW577496 AW577504 AW842725 AW842666 AW864691 AW997722 AW842662 BE009233 BE087809 BE083196 AA287768AW939691 AW815631 BE001453AW841903 BE077613AW577500 BE081479AW992558 BE011065AW843187AW867990AW898296 BE074339 AA501697 AW749997 BE076249 AW867991 BE085718 AW994607 BE010678 BE075436 AW386825 AA484467 BE081144 AW577492 AW997932 AW899089 AW842706 AW890727 AW843175 BE075428 AW843155 AW842679 AW842708 BE069915 AW842721 AW438792 AI251478 BE069911 BE067054 BE079889 BE075453 BE069827 AA491920 BE170606 BE182305 BE080052 AW843406 BE011075 BE075969 AA525261 AW391518 BE079202 AA658195 BE076138 AW799901 AA493859 AW992510 BE011810 AA508724 BE075488 BE075661 AA258982 BE078726 BE069914 AA213698 BE075376 AA484600 AW580999 BE077872 AA503571 AW884724 AW880124 AW868454 AW577502 AW577489 AW799829 AW992545 BE075806 AW994606 BE350368 AA557836 BE077682 AW844660 AW883431 BE085872 AW838887 AW843890 AW868404 AA578417 BE074115 AW842680 AW277193 AW890728 AW605111 BE093940 AW890710 BE085560 AW868180 AW896778 BE069925 BE011054 BE075965 AW842668 AW868310 BE011071 BE075429 AW843152 AW905848 BE075397 AW842762 BE075402 BE077950 AW837810 BE079998 BE183965 BE075431 AW815917 AW998359 AW799883 AW603782 AA557480 AW841444 BE075915 AA548034 AW843393 AW391559 BE083265 AW939721 AW800857 AW079109 AW364901 AI435993 AA985526 AW799848 BE182463 AA776111 AW799915 BE008399 BE075377 AW577809 BE010272 BE182443 BE010296 AW577806 BE008415 BE184036 BE076597 A1817413 AW795053 AW896761 AW841433 BE182458 AW603796 AW842676 BE085455 AW884879 BE075414 AW838836 AW878273 AW998088 AW799778 AW899125 BE082247 AA774870 BE001401 BE001485 AW817297 AW796670 AW394063 BE001396 AW394070 AW603797 BE182447 AW582483 AW843283 AW749520 AW867449 AW899274 AW578232 AW603765 AW843919 AW578235 BE184139 AW997742 BE183923 BE084210 AW802033 AW748724 AW939018 AW997459 AW842742 AA213697 BE182308 BE011078 AW607702 AW882623 BE080016 AW580994 BE076531 AA443462 AW607407 AW883382 AW939399 AW605627 AW844615 AW939724 AW815931 AW883765 AA287421 BE075626 AW946171 AW841445 AW797994 AW815957 AA683300 AW369004 BE075368 BE081560 AW605626 AW939398 AA507280 AA506317 AW841230 AW992519 AA465332 AA425246 BE090234 BE090236 AA483259 AA451961 AA535566 AA506406 AA888571 AA503568 AA507130 AA532944 AA501672 BE168634 AA492022 AA507662 AW842286 AA494226 AA776038 AA442419 AW579900 BE171816 AA863065 AA491916 AA447490 AA461423 AA434543 AA243279 AW997466 AW603740 BE000295 AA658571
TABLE 15C
Pkey Unique number correεpondmg to an Eoε probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numberε "Dunham I etal " refers to the publicalon entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLpoεition
400715 8118885 Minuε 80151-80297
400736 8118985 Pluε 143447-143851
401008 8117391 Minus 81421-81551,82364-82512,82862-82938
401069 3927852 Minus 45682-45831
401375 7417809 Minus 6121-6766
401405 7768126 Minus 69276-69452,6954869958
401539 8072433 Minus 62028-62608
401557 8099866 Minus 112785-112924
401654 9097132 Minus 64695-64797
401940 3738108 Plus 153460-153592
402025 7547159 Plus 173835-173998
402442 9796503 Plus 141714-141842,142010-142122
402682 8138477 Minus 147522-147795
402796 3646083 Minus 6126-6265,6416-6689
402967 5360987 Minus 33518-34546
403038 7717439 Minus 290021-290284
403055 8748904 Minus 109532-110225
403310 8139936 Minus 183883-184026
403397 9438368 Minus 84481-84655
403839 4176355 Plus 21201-22223
404110 9212839 Minus 18344-18510
404495 8151634 Minus 59449-60477
404534 8247909 Minus 147853-148086
404630 9796665 Plus 74495-74715
404649 9796926 Minus 100027-100399
404680 9797204 Minus 159810-159979,160213-160321,161023-161304,162862-163140,164490-164644,166404-166530,166936-167083,167392-167522
404914 7341760 Plus 92603-92827
405417 4753290 Minus 50704-51499
405454 7656675 Plus 133807-134053
405510 7630909 Minus 101028-101174
405514 9454624 Plus 35953-36151
405536 9795661 Plus 164091-164162,164397-164516,166720-166790,167785-167935
406016 8272661 Plus 41341-41940
406410 9256394 Minus 115806-116104
406464 9789674 Plus 72161-72562
406562 7711584 Plus 37316-37426
TABLE 16A 200 GENES DOWN-REGULATED IN CERVICAL CANCER COMPARED TO NORMAL ADULT CERVIX
Table 16A shows 200 genes down-regulated in cervical cancer compared to normal adult cervix These were εelxted aε for Table 15A, except that the numerator and denominator were switched, the median value amongst normal cervices was greater than or equal 40 units, and the ratio was greater than or equal to 30 (ι e 3-fold down-regulated in tumor vs normal cervix)
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xceεεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of cervical cancer to nomial cervix
Pkey ExAccn UnigenelD Unigene Title R1
453596 AA441838 Hs 62905 hypothetical protein FU14834 181
443812 R37257 Hs 184780 ESTs 168
420923 AF097021 Hs 273321 differentially expressed in hematopoietic lineages 136
414422 AA147224 Hs 337232 Homx box A13 131
420058 AK001423 Hs 94694 Homo sapiens cDNA FU10561 fis, clone NT2RP2002672 129
412639 AW961284 Hs 296235 ESTs 124 418994 AA296520 Hs.89546 selxtin E (endothelial adhesion molxule 1) 12.4
407938 AA905097 Hs.85050 phospholamban 11.3
410544 AI446543 Hs.95511 ESTs 11.3
413802 AW964490 Hε.32241 ESTs, Weakly similar to S65657 alpha-1 C-adrenergio rxe 11.1
423690 AA329648 Hs.23804 ESTs, Weakly similar to PN0099 son3 protein [H.sapieπs] 11.0
420674 NM 000055 Hs.1327 butyrylcholinesterase 10.9
453060 AW294092 Hs.21594 hypothetical protein MGC15754 10.6
424765 AA428211 Hs.284256 hypothetical protein FU 14033 similar to hypoxia indu'ci 10.5
452106 AI141031 Hε.21342 ESTs 9.5
428780 AI478578 Hs.50636 ESTs 9.5
431706 AI816086 Hs.296341 adenyiyl cyclase-assxiated protein 2 9.2
419589 AW973708 Hε.201925 Homo sapiens cDNA FLJ13446 fis, clone PLACE1002968 9.0
430468 NM 004673 Hs.241519 angiopoietin-like 1 9.0
443790 NM 003500 Hs.9795 xyl-Coenzyme A oxidase 2, branched chain 8.7
448944 AB014605 Hε.22599 atrophin-1 interxting protein 1; xtivin rxeptor inte 8.6
401486 NA C4000647*:gi|4758508|ref|NP_004253.1| airway trypsin-li 8.4
417511 AL049176 Hε.82223 chordin-like 8.3
429900 AA460421 Hs.30875 ESTε 8.2
411908 L27943 Hs.72924 cytidine deaminase 8.0
408134 AK000184 Hs.42945 xid εphingomyelinase-like phosphodiesterase 8.0
448543 AW897741 Hs.21380 Homo sapiens mRNA; cDNA DKFZp586P1124 (from clone DKFZp 8.0
437846 AA773866 Hε.244569 esophagus cancer-related gene-2 8.0
421666 AL035250 Hs.1408 endothelin 3 7.9
450164 AI239923 Hs.30098 ESTs 7.9
412642 BE244598 Hs.809 hepatocyte growth fxtor (hepapoietin A; scatter fxtor 7.7
425608 AA360486 Hs.92448 ESTs 7.6
442748 AI016713 Hs.135787 ESTε 7.3
415672 N53097 Hs.193579 ESTε 7.2
414175 AI308876 Hs.103849 hypothetical protein DKFZp761D112 7.2
409601 AF237621 Hs.80828 keratin 1 (epidermolytic hyperkeratosis) 7.0
424634 NM 003613 Hs.151407 cartilage intermediate layer protein, nucleotide pyroph 6.7
414214 D49958 Hε.75819 glycoprotein M6A 6.5
436637 AI783629 Hs.26766 ESTε 6.5
408621 AI970672 Hs.46638 chromosome 11 open reading frame 8 6.5
432101 AI918950 Hs.123642 EphA3 6.3
458440 AI095468 Hs.135254 Homo sapiens clone 1 thrambospondin mRNA, complete eds 6.3
424153 AA451737 Hε.141496 MAGE-like 2 6.3
420228 R25023 Hε.12369 ESTs 6.2
418390 AF133820 Hε.84665 titin immunoglobulin domain protein (myotilin) 6.1
444931 AV652066 Hε.75113 general transcription fxtor IIIA 6.1
449394 AA004368 Hs.18160 Homo sapiens cDNA FLJ11550 fis, clone HEMBA1002970 6.1
425849 AJ000512 Hs.296323 serum/glucxorticoid regulated kinase 6.1
410425 BE278367 Hε.63510 KIAA0141 gene product 6.0
410765 AI694972 Hs.66180 nucleoεome assembly protein 1-like 2 6.0
424973 X92521 Hs.154057 matrix metalloproteinase 19 6.0
436547 AJ297351 Hs.30824 leucine zipper transcription fxtor-like 1 5.9
429414 AI783656 Hs.202095 empty spirxles (Drasophila) homolog 2 5.9
440594 AW445167 Hs.126036 ESTs 5.9
452768 AW069459 Hs.61539 ESTs 5.9
427669 AW451832 Hs.255938 ESTs, Moderately similarto KIAA1200 protein [H.sapieπs 5.9
448533 AL119710 Hs.21365 nucleosome assembly protein 1-like 3 5.9
425010 T16837 Hs.4241 ESTs 5.9
426342 AF093419 Hs.169378 multiple PDZ domain protein 5.8
437980 R50393 Hs.278436 KIAA1474 protein 5.8
425292 NM 005824 Hs.155545 37 kDa leucine-rich repeat (LRR) protein 5.7
404097 NA C5000242*:gi|9369379|gb|AAF87128.1|AC006434_24 (AO00643 5.7
422546 AB007969 Hs.301478 KIAA0500 protein 5.7
445872 AI681573 Hε.288671 Homo sapiens cDNA FU11997 fis, clone HEMBB1001458 5.7
429999 AI761902 Hε.99597 ESTs 5.6
453354 W55946 Hs.234863 Homo sapienε cDNA FU12082 fiε, clone HEMBB1002492 5.6
442082 R41823 Hs.7413 ESTs 5.5
452073 AA625150 Hε.82098 ESTs 5.4
430032 AW936136 Hs.99610 ESTs 5.4
408767 AA057279 Hs.211928 ESTs 5.4
433234 AB040928 Hs.65366 KIAA1495 protein 5.3
431708 AI698136 Hs.108873 ESTs 5.3
421200 AA284811 Hs.264433 ESTs 5.2
435133 AJ010482 Hs.31412 Homo sapiens cDNA FU11422 fis, clone HEMBA1001008 5.2
409643 AW450866 Hs.257359 ESTs 5.1
416676 AW392022 Hs.79507 KIAA0582 protein 5.1
420357 U94333 Hs.97199 ∞mplement component C1q rxeptor 5.0
417355 D13168 Hs.82002 endothelin receptor type B 5.0
423448 AK000776 Hs.128753 Homo sapiens cDNA FU20769 fis, clone COL06674 5.0
430965 AA489732 Hs.154918 ESTε 4.9
419968 X04430 Hs.93913 interleukin 6 (interferon, beta 2) 4.9
447471 AF039843 Hs.18676 εprauty (Drasophila) homolog 2 4.8
404485 NA Target Exon 4.8
429594 AK001128 Hs.210297 Homo sapiens cDNA FU10266 fis, clone HEMBB1001024 4.8
417692 R09338 Hs.50724 Homo sapiens cDNA FU10934 fis, clone OVARC1000640 4.8
432304 AA932186 Hs.69297 ESTs 4.7
430895 U66581 Hs.248121 G protein-coupled rxeptor 22 4.7
448851 AI582207 Hs.177166 ESTs 4.7
405523 C8001409*:gi|7441226|pir||S31212collagen alpha 1(XIV) 4.7 450656 AA010539 Hs 18912 ESTs 46
422942 AF054839 Hs 122540 tetraspan 2 46
401479 T49304 Hs 110950 Rag C protein 46
444192 AW469413 Hs 151145 ESTs 46
439648 AW780192 Hs 267596 ESTs 45
410378 R23324 Hs 41693 DnaJ (Hsp40) homolog, subfamily B, member 4 45
444702 AI220122 Hs 326560 hypothetical protein MGC2780 45
410909 AW898161 Hs 53112 ESTs, Moderately similar to ALU8.HUMAN ALU SUBFAMILY SX 45
452249 BE394412 Hε 202095 empty spiracles (Drasophila) homolog 2 45
430376 AW292053 Hs 12532 chromosome 1 open reading frame 21 45
411037 BE145915 Hs 99472 ESTs 44
442803 AI675298 Hs 199917 ESTs 44
414831 M31158 Hs 77439 protein kinase, cAMP-dependent regulatory, type II, be 44
400628 NA C10001871* gι|1705533|sp|P32018|CA1E_CHICK COLLAGEN ALP 43
414629 AA345824 Hs 76688 carboxyleεterase 1 (monxyte/mxrophage seπne esteraεe 43
437110 AL049240 Hs 144995 ESTs 42
410646 W79408 Hs 50745 ESTs 42
456304 AI820973 gb nc21c02 y5 NCI.CGAP.Pr1 Homo sapiens cDNA clone, mRN 42
401270 Target Exon 42
419447 BE092696 Hε 75928 ESTs 42
414807 AI738616 Hs 77348 hydroxyprostaglandin dehydrogenase 15-(NAD) 42
427019 AA001732 Hs 173233 hypothetical protein FLJ 10970 42
434469 AA634806 gb ab28c02 r1 Stratagene lung (937210) Homo sapiens cDN 41
444618 AV653785 Hs 173334 ELL-RELATED RNA POLYMERASE II, ELONGATION FACTOR 41
418947 W52990 Hs 22860 ESTs 41
416434 AW163045 Hs 79334 nuclear fxtor, interleukin 3 regulated 40
454736 BE184348 gb CM0-HT0676-010500-355-e11 HT0676 Homo sapienε cDNA, 40
407945 X69208 Hs 606 ATPase, Cu transporting, alpha polypeptide (Menkes εynd 40
447499 AW262580 Hs 147674 protocadhenn beta 16 40
430686 NM 001942 Hs 2633 desmoglein 1 40
409882 AJ243191 Hs 56874 heat shxk 27kD protein family, member 7 (cardiovascula 39
419047 AW952771 Hs 90043 ESTs 39
414272 AI651603 Hs 46988 ESTs 39
443808 AW377736 Hs 12420 ESTs 39
426883 H21520 Hs 35088 ESTs 39
410659 AI080175 Hs 68826 ESTs 39
431292 AA370141 Hs 2281 chromcgranin B (sxretogranin 1) 39
432181 AA527650 Hs 156037 ESTs 39
422890 Z43784 Hs 75893 ankyπn 3, node of Ranvier (ankyπn G) 38
453296 AA034413 Hs 62560 ESTs 38
400878 NA Target Exon 38
401103 NA C12001233 gι|7305361|ref|NP 038652 1| otogelin [Mus mus 38
436670 AI690021 Hs 201536 ESTs 37
432251 AW972983 Hs 232165 polycythemia rubra vera 1 , cell surfxe rxeptor 37
408793 BE258371 Hs 254660 ESTs 37
419093 AI804054 Hs 112885 spinal cord-deπved growth fxtor-B 37
434844 AF157116 Hs 22350 hypothetical protein LOC56757 37
450776 NM.007250 Hs 320861 Kruppel like factor 8 37
437140 AA312799 Hs 283689 xtivator of CREM in testiε 36
418421 R58620 Hs 85050 phospholamban 36
443476 AW068594 Hs 133878 ESTs, Weakly similar to YCD1.HUMAN HYPOTHETICAL PROTEIN 36
417194 N53793 gb yz07a01 r1 Soares multiple sclerosis 2NbHMSP Homo sa 36
443567 AI077540 Hs 134090 ESTs 36
451879 AI821030 gb yb52f11 y5 Stratagene ovary (937217) Homo sapiens cD 36
421013 M62397 Hs 1345 mutated in colorectal cancers 35
451896 AF196304 Hs 27197 SUMO-1-spxιfic proteaεe 35
413237 AI468574 Hs 171965 ESTs 35
424636 AA453734 Hs 10198 ESTs 35
432660 AI288430 Hs 64004 ESTε 35
414681 AL079440 Hε 74002 nuclear receptor coxtivator 1 35
400802 NA Target Exon 35
430015 AW768399 Hε 112157 ESTε 35
451978 AW813747 Hs 27371 Homo εapienε mRNA, cDNA DKFZp566J123 (from clone DKFZpδ 35
449088 AI654048 Hε 196556 ESTε 35
425113 AI936992 Hε 154658 plxkstπn and Sx7 domain protein 35
458459 AI124553 Hs 48965 Homo sapiens cDNA FU21693 fis, clone COL09609 35
420249 BE262895 Hs 276916 nuclear rxeptor subfamily 1, group D, member 1 35
401159 NA Target Exon 35
442789 AW904361 Hs 131191 ESTs, Weakly similar to ALU7 HUMAN ALU SUBFAMILY SQ SEQ 35
426083 AW962712 Hs 126712 ESTs, Weakly similar to AF1910201 E2IG5 [H sapiens] 34
407118 AA156790 Hs 262036 ESTs, Weakly εimilar to Z223.HUMAN ZINC FINGER PROTEIN 34
423587 AA328074 Hs 284256 hypothetical protein FU14033 εimilar to hypoxia mduci 34
443178 AI631241 Hs 47312 ESTε 34
430694 AA810624 Hs 30936 ESTs, Weakly similar to H2BH.HUMAN HISTONE H2B H [H sap 34
423073 BE252922 Hs 123119 MAD (mothers against dxapeπtaplegic, Drasophila) homol 34
437950 U79244 Hs 112642 ESTs 33
419368 AI753518 Hs 209464 KIAA1604 protein 33
447335 BE617695 Hs 286192 hypothetical protein FU20940 33
451398 AI793124 Hs 144479 ESTs 33
452814 AI092790 Hs 334703 hypothetical protein FU14529 33
407570 Z19002 Hs 37096 zinc finger protein 145 (Kruppel like, expresεed in pro 33
412295 AW088826 Hs 117176 poly(A)-bιndιng protein, nuclear 1 33
447261 NM.006691 Hs 17917 extrxellular link domam-containmg 1 33 444216 D25303 Hs 222 integπn, alpha 9 33
418771 AA807881 Hs 25329 ESTs 33
433036 AA574091 Hs 105964 ESTs 32
404584 Target Exon 32
404195 NM.015718* Homo sapiens NADPH oxidase 3 (NOX3) mRNA V 32
428819 AL135623 Hs 193914 KIAA0575 gene product 32
425198 AA352090 Hs 128003 hypothetical protein FU21213 3 1
420833 R47948 Hs 188732 ESTs 3 1
413156 AA127133 gb zl87e03 r1 Stratagene colon (937204) Homo sapiens cD 31
413607 T64741 gb yc48f11 r1 Stratageπe liver (937224) Homo sapienε cD 31
443960 AI093577 Hs 255416 hypothetical protein FLJ21986 31
428790 AF023456 Hs 193558 protein phosphatase, EF hand calcium binding domain 2 31
434520 AA205273 Hs 177011 hypothetical protein 31
432247 AA531287 Hs 105805 ESTs 31
429303 AW137635 Hs 44238 ESTs, Weakly similarto S65657 alpha-1 C-adrenergic rece 31
439734 AC005013 Hs 149 cAMP responεe element-binding protein CRE-BPa 31
433546 AI075877 Hs 125461 hypothetical protein FU11539 30
430317 AB020645 Hs 239189 glutammaεe 30
425130 AA448208 Hs 99163 ESTε 30
444195 AB002351 Hs 10587 KIAA0353 protein 30
409007 AL122107 Hs 49599 Homo εapienε mRNA cDNA DKFZp434G0827 (from clone DKFZp 30
453773 AL133761 gb DKFZp761C1413_r1 761 (synonym hamy2) Homo sapiens c 30
442974 AI025670 Hs 109308 ESTs, Weakly similar to leucine-πch glioma-inactivated 30
446936 H10207 Hs 47314 ESTs 30
454086 AW885909 Hs 6975 PR01073 protein 30
420271 AI954365 Hs 42892 ESTs 30
435545 AA687415 Hs 28107 ESTs 30
445175 AV652851 Hs 20255 ESTs 30
TABLE 16B
Pkey Unique Eoε probeεet identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT Number Accesεions
413156 135116 1 AA127133 AA384396 AW958912 T72119
413607 1379911 1 T64741 BE158393 BE152805
417194 1657323 1 N53793 N53716 53739
434469 387447 1 AA634806 C18732 AA729161 AA729860
451879 888642.1 A1821030 T47126 AI821318
453773 980699 1 AL133761 AL133767
454736 1232235 1 BE184348 AW817453 BE011068
456304 176820.1 AI820973 AI734077 AI820984 AA225796 AA225060 AA225101
TABLE 16C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numberε "Dunham 1 etaP i εequence of human chromoεome 22 " Dunham 1 et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exonε were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400628 3818355 Plus 41851-41984
400802 8567867 Minus 174571-174856
400878 9864757 Plus 31493-32842
401103 8568122 Minus 98330-98449
401159 6067118 Minus 3180-3953
401270 9797168 Minus 141659-141813
401486 7341763 Plus 32585-32756,36281-36540,40791-40933,44018-44179
404097 7770701 Plus 55512 55781
404195 3805917 Minus 39186-39332
404485 8096921 Plus 75166-75264,124036-124232
404584 9857511 Plus 138651-139153
405523 9454643 Plus 114550-114688,117265-117407,119490-119599,123237-123395,131140-131217
TABLE 17A 605 genes upregulated in testicular cancer relative to normal body tissues
Table 17A lists about 605 genes upregulated in cervical cancer relative to normal body tissues that are likely to encode proteins amenable to modulation by small molxules peptides, or antibodies These genes were selxted from 59680 probeεets on the Eos/Affymetnx Hu03 Genxhip array Gene expreεsioπ data for exh probeset obtained from this analysis was expreεεed aε average intensity (Al), a normalized value reflxting the relative level of mRNA expression The pratem products of these genes often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death-domain, 7tm, phosphatase, or lon.transporter) Certain predicted protein domains are noted
Pkey Unique Eos prabeset identifier number
ExAccn Exemplar xceεεion number, GenBank xcession number
UniGenelD UniGene number
Pred ProtDomaiπs Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280) UniGene Title UniGene gene title
R1 95th percentile of cervical cancer Als divided by the 50th percentile of normal tisεue Alε, where the 10th percentile of all normal tissue Als was subtrxted from both the numerator and denominator
Pkey, ExAccn, UnigenelD, Unigene Title, Pred ProtDomams, R1
408522 AI541214, Hs 46320, Small proliπe-πch protein SPRK [human, , none.Cornifin, 33942 422168, AA586894, Hs 112408, S100 calcium binding protein A7 (psoπas, efhand S_100,TM=M SS=N, 3305 424098, AF077374, Hs 139322, small proline πch protein 3, Cornifin,TM=M,SS=N, 32856
422158, L10343, Hs 112341, protease inhibitor 3, skin deπved (SKAL, wap,TM=M,SS=Y, 29604
433091, Y12642, Hs 3185, lymphxyte antigen 6 complex, Ixus D, UPAR.LY6 toxin Actιvm_recp,TM=M,SS=Y, 2795054945
421948, L42583, Hε 334309, keratin 6A, filament,RhoGAP,DUF286,bZIP,Tropomyo8in,tubulm,DUF164,TBCA,Collagen,TM=M,SS=N, 26778
446292, AF081497, Hs 279682, Rh type C glycoprotein, Ammonιum_transp,FxCD,TM=Y,SS=M, 26 1133829 407242, M18728 , gb Human πoπspxific crassrexting antig, ιg,TM=M,SS=M, 23382
424687, J05070, Hε 151738, matnx metalloproteinase 9 (gelatinase B, fn2,hemopexιn,Peptιdase_M10„ 22522
412719, AW016610, Hs 816, ESTs, πone.none, 21 198
406690, M29540, Hs 220528, carcmoembryonie antigen related cell ad, ιg,TM=M,SS=M, 20028
402075, , , ENSP00000251056* Plasma membrane calcium, none,, 19038 431958, X63629, Hs 2877, cadhenn 3, type 1, P-cadheπn (plxenta, cadhenn,Cadheππ_C_term,TM=Y,SS=M 1792061281
412471, M63193, Hs 73946, endothelial cell growth fxtor 1 {plate!, Glycos_traπsf_3,Glycos_trans_3N,TM=M,SS=M, 178978979
417308, H60720, Hs 81892, KIAA0101 gene product, none,TM=M,SS=N, 1708333333
429259, AA420450, Hs 380088, Plakophilin, none.none, 1708235294
417079, U65590, Hs 81134, interleukin 1 rxeptor antagonist, IL1„ 1691568628 439926, AW014875, Hε 137007, ESTε, none.none, 1669
419693, AA133749, Hs 301350, FXYD domain containing ion transport reg, ATP1G1_PLM_MAT8,TM=Y,SS=M, 16365
413753, U17760, Hs 75517, laminin, beta 3 (nice (125kD), kalinm, lamιnιn_EGF,lamιπιn_Nterm„ 1575294118
413278, BE563085, Hs 833, interferon εtimulated protein, 15 kDa, ubiquitin,, 1548600509
401781, , , Target Exon, filament,TM=M,SS=N, 1543668831 420440, NM.002407, Hε 97644, mammaglobin 2, Uteroglobin,, 15394
441633, AW958544, Hs 112242, normal mucosa of esophagus spxific 1, noπe,TM=M,SS=M, 15 12264151
452240, AI591147, Hs 61232, ESTs, none.none, 1463
428957, NM 003881, Hs 194679, WNT1 inducible signaling pathway protein, tsp_1,vwc,IGFBP,TM=M,SS=M, 1449772727
414987, AA524394, Hs 294022, hypothetical protein FU14950, SH2,TM=M,SS=N, 144389313 432374, W68815, Hs 301885, Homo εapienε cDNA FU11346 fis, clone PL, none.none, 1400909091
400289, X07820, Hs 2258, matnx metalloproteinase 10 (stromelysin, hemopexιn,Peptιdase_M10,Astxιn„ 13824
414812, X72755, Hs 77367, monokine induced by gamma interferon, IL8,TM=M,SS=Y, 137754386
421552, AF026692, Hs 105700, sxreted fπzzled related protein 4, Fz,NTR„ 1374595843
400284, , , NM 000125* Homo sapiens eεtrogen recepto, hormone_rec,zf-C4,Oest rxep,TM=M,SS=M, 1331578947 428227, AA321649, Hs 2248, small inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 1305294118
411274, NM 02776, Hs 69423, kallikrein 10, tτypsιn,TM=M,SS=N, 13038
406687, M31126, Hs 352054, matnx metalloproteinase 11 (stromelysin, hemopexιn,Peptιdase_M10„ 1300311527
427666, AI791495, Hs 180142, calmodulm like skin protein (CLSP), efhand,TM=M,SS=N, 1279
400301, X03635, Hs 1657, estrogen rxeptor 1, F-box,hormone rec,zf-C4,OesLrecep,adh_zιnc,ketoxyl syπt.pp-bindmg Acyl transf,Thιoesterase,ketoxyl- synLC,AAA,E7,RFX_DNA_bmdιng,TM=M,SS=N, 12472
410001, AB041036, Hs 57771, kallikrein 11, trypsιn,TM=M,SS=M, 1247
422310, AA316622, Hε 98370, cytochrome P450, εubfamily IIS, polypept, none,pkιnase,fn3,ιg, 1228597122
430630, AW269920, Hs 2621, cystatin A (εtefiπ A), cyεtatιn,TM=M,SS=N, 12 13379205
437044, AL035864, Hs 69517, differentially expressed in Fancom's an, none,TM=M,SS=M, 1204945055 418462, BE001596, Hs 85266, integπn, beta 4, frι3,ιntegπn_B,Calx-beta,EGF,TM=M,SS=M, 11 95538462
443859, NM.013409, Hs 9914, fbllistatin, kazal,, 11 95467422
426350, NM.003245, Hs 2022, transglutaminase 3 (E polypepbde, prote, Transglutamιn_N,Transglutamιn_C,TransgluLcore,TM=M,SS=N, 11 61
408243, Y00787, Hs 624, interleukin 8, HLH,PAS,IL8,TM=M,SS=N, 11 564
444781, NM.014400, Hs 11950, GPI-anchored etastaεiε-aεε∞iated prote, UPAR_LY6,lxtamase_B, 11 55285714 428484, AF104032, Hs 184601 , εolute earner family 7 (cationic ammo , aaj)ermeases,pyπdoxal_deC,bromodomaιn,PHD,MBD,AT_hook,DDT,PI3_PI4_kιnase,FAT,FATC,BolA,RUN,TM=M,SS=N, 11 47956989
418663, AK001100, Hs 41690, desmxollin 3, cadheππ,Cadhenn_C_term,none, 11 456
433001, AF217513, Hε 279905, clone HQ0310 PRO0310p1, none,, 11 45352113
423217, NM 000094, Hs 1640, collagen, type VII, alpha 1 (epidermolys, Kunitz BPTI,frι3,vwa,Collagen,beta-lxtamase,TM=M,SS=M, 11 32234432 428970, BE276891, Hs 194691, retinoicxid induced 3 (RAIG1), etabo, 7tm_3,TM=Y,SS=M, 11 28686327
424834, AK001432, Hs 153408, Homo sapiens cDNA FLJ10570 fis, clone NT, none.none, 11 076
451541, BE279383, Hs 26557, plakophilin 3, ArmadιlIo_seg,TM=M,SS=N, 11 0381579
418478, U38945, Hs 1174, cyclm-dependent kinase inhibitor 2A (me, ank„ 11
423673, BE003054, Hs 1695, matnx metalloproteinase 12 (mxrophage , hemopexιn,Peptιdase_M10,TM=M,SS=M, 11 425071, NM.013989, Hs 154424, deiodinase, lodothyronine, type II, T4_deιodιnase,TM=M,SS=Y, 1093859649
437938, AI950087, Hs 369628, gb wq05c02 x1 NCI_CGAP_Kιd12 Homo sapien, none.none, 1078064516
425367, BE271188, Hs 155975, protein tyrosine phosphatase, receptor t none,TM=M,SS=Y, 1074825175
439706, AW872527, Hs 59761, ESTs, Weakly similar to DAP1 HUMAN DEATH, none.none, 10542
437897, AA770561, Hs 146170, hypothetical protein FU22969, zf-DHHC,noπe, 1049538462 431629, AU077025, Hs 265827, interferon, alpha-mducible protein (clo, none,TM=M,SS=Y, 1048210736
411558, AA102670, Hs 70725, gamma-aminobutyric xid (GABA) A rxepto, Neur_chan_LBD,Neur_chan_memb,TM=Y,SS=M, 1026714286
409142, AL136877, Hs 50758, SMC4 (structural maintenance of chromoso, ABC tran,M,SMC_N,SMC C,DUF164,none, 10 142
421508, NM.004833, Hs 105115, absent in melanoma 2, PAAD_DAPIN,HIN,TM=M,SS=N, 10 1
418641, BE243136, Hs 86947, a disintegnn and metalloproteinase doma, dιsιntegπn,Reprolyειn,Pep_M12B_propep,EGF,TM=Y,SS=M, 10072 425397, J04088, Hs 156346, topoisomerase (DNA) II alpha (170kD), DNAjyraseB,DNA_topoisolV,HATPase_c„ 9996363636
414035, Y00630, Hs 75716, senne (or cysteine) proteinase inhibito, seφiπ,, 9896825397 421506, BE302796, Hs 105097, thymidme kinase 1, soluble, TK,TM=M,SS=N, 9888888889 407786, AA687538 Hs 38972, tetraspan 1, transmembrane4,TM=Y,SS=M, 9876056338 424441, X14850, Hs 147097, H2A histone family, member X, histone.CBFD.NFYB.HMF,, 9851635514 438091, AW373062, Hs 351546, nuclear rxeptor subfamily 1, group I, m, hormoπe_rx,zf-C4,noπe, 9840720222
413859, AW992356, Hs 8364, Homo sapienε pyruvate dehydrageπaεe kina, SAM_PNT,none, 9823170732
408000, L11690, Hs 198689, bullous pemphigoid antigen 1 (230/240kD), efhand,spxtnn,GAS2,SH3,Plxtιn,RA,Xylose_ιsom,FlιD,bZIP,Tropomyosιn,Myc- LZ,M,ldh_C,CH,AIP3,TM=M,SS=N, 9812 409893, AW247090, Hs 57101 , minichromosome maintenance deficient (S , MCM,aldo_keLred,TM=M,SS=N, 9787878788 442599, AF078037, Hs 324051, RelA assxiated inhibitor; SH3,ank,TM=M,SS=N, 9637037037 425650, NM.001944, Hs 1925 desmoglein 3 (pemphigus vulgaπs antigen, cadheπn,TM=M,SS=M 9596 417900, BE250127, Hs 82906, CDC20 (cell diviεion cycle 20, S cerevi, WD40,TM=M,SS=N, 9558 444946, AW139205, Hs 156457, hypothetical protein FU22408, abhydralase,abhydrolase_2,TM=Y,SS=M, 955
421481, AW391972, Hs 104696 KIAA1324 protein, none,TM=M,SS=M, 9529085873 408591, AF015224, Hs 46452, mammagtobin 1, Uteroglobιn,TM=M SS=M, 9506 444381, BE387335, Hs 283713, hypothetical protein BC014245, Collagen,TM=M,SS=M, 9477961433 444006, BE395085, Hs 334762, type I transmembrane protein Fn14, Idl recepLa.PKD.MHC l,TM=M SS=Y, 9415151515 413719, BE439580, Hs 75498, small inducible cytokine subfamily A (Cy, IL8„ 9408
424364, AW383226, Hs 163834, ESTs, Weakly similar to G01763 atrophiπ , ras,TM=M,SS=N, 936 429002, AW248439 Hε 2340, junction plakoglobm, Armadιllo_seg,TM=M,SS=N, 9315693431 421379, Y15221, Hs 103982, small inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 931 418004, U37519, Hs 87539, aldehyde dehydrogenase 3 family, member , aldedh,TM=M,SS=M, 929 454034, NM.000691 , Hs 575, aldehyde dehydrogenase 3 family, member , aldedh,, 9264
417389, BE260964, Hs 82045, midkine (neuπte growth-promoting fxtor; PTN MK,TM=M,SS=Y, 9241561181 445033, AV652402, Hs 72901, cyclm-dependent kinase inhibitor 2B (p1, ank„ 9207272727 443426 AF098158, Hs 9329, chromosome 20 open reading frame 1, none,TM=M,SS=N, 9 195167286 439223, AW238299, Hs 250618, UL16 binding protein 2, ldl_recepLa,PKD,MHC l,TM=M,SS=Y, 9108 428758 AA433988 Hs 98502, CA125 antigen, mucin 16, SEA,TM=Y,SS=N, 9028
421777, BE562088, Hε 108196, HSPC037 protein, none,TM=M,SS=N, 9004
448988, Y09763, Hs 22785, gamma-aminobutyπc xid (GABA) A rxepto, Neur chan.LBD.Neur chan_memb,TM=Y,SS=M, 9001096491 418969, W33191, Hs 28907, hypothetical protein FU20258, SH3,TM=M,SS=N, 8942 455601, AI368680, Hs 816, SRY (sex determining region Y) box 2, HMG.box,, 887 429211, AF052693, Hs 198249, gap junction protein, beta 5 (connex 3, connexιn,TM=Y,SS=M, 877131783
456906, AF117646, Hs 156637, Cas Br-M (muπne) xtropic retroviral tr; zf C3HC4,CbLN,Cbl_N2,Cbl_N3,TM=M,SS=N, 8738 430397, AI924533, Hs 105607, bicarbonate transporter related protein , HC03_cotransp,TM=Y,SS=N, 8736 417034, NM 006183 Hs 80962, neurotensin, none,, 8592 429083, Y09397, Hs 227817, BCL2 related protein A1, Bcl-2,TM=M,SS=N, 8536 408113, T82427, Hs 194101, Homo sapiens cDNA FU20869 fis, clone A, 7tm 3,none, 849
439285, AL133916, Hs 47860, hypothetical pratem FU20093, ig pkιnase,LRR,LRRNT,LRRCT,none, 8460655738 409420, Z15008, Hs 54451, laminin, gamma 2 (nicem (100kD), kalini, laminin.B.lamimn.EGF,, 8414 438746, AI885815, Hs 184727, Human melaπoma-ass∞iated antigen p97 ( , transferπn.Guanylate kιn,PDZ,SH3, 8376205788 439606, W79123, Hs 58561, G protein-coupled rxeptor 87, 7tm_1,TM=Y,SS=M, 837 430486, BE062109, Hs 241551, chloride channel, calcium xtivated, fam, none,TM=Y,SS=M, 8364
429170, NM.001394, Hs 2359, dual εpxificity phosphatase 4, Rhodanese,DSPc,Y_phosphatase,Rιbosomal_S3_N,TM=M,SS=N, 8266 417771, AA804698, Hs 82547, retinoic xid rxeptor responder (tazara, none.none, 8248314607 431620, AA126109, Hs 264981, 2'-5'-olιgoadenylate synthetase 2 (69-71, NTP_transf_2,TM=M,SS=N, 8 156 412270, AC005262, Hs 73797, guanine nucleotide binding protein (G pπ G-alpha,arf,TM=M,SS=N, 8 142857143 448733, NM.005629, Hs 187958, solute earner family 6 (neurotransmitte, SNF,TM=Y,SS=N, 8 137559809
427557, NM.002659, Hs 179657, plas inogen xtivator, urakiπase rxepto, UPAR_LY6,ET,PLA2_ιnh„ 8043478261 424439, AA579635, Hs 1770, ligase I, DNA, ATP-dependent, DNAJigase,, 8038194444
418322, AA284166, Hs 84113, cyclm-dependent kinase inhibitor 3 (CDK, Y_phosphatase,DSPc,TM=M,SS=N, 8024752475 453857, AL080235, Hs 35861 , Ras-induced senescence 1 (RIS1), none,TM=Y,SS=M, 8 424046, AF027866, Hs 138202, seπne (or cysteine) proteinase inhibito, serpιn,TM=M,SS=N, 7982
418526, BE019020, Hs 85838, solute camerfamily 16 (mon∞arboxylic, none,TM=Y,SS=M, 7973684211 413219, AA878200, Hs 118727, Homo sapiens cDNA FU13692 fis, clone PL, HLH.death.TNFR c6,Acyl-CoA_hydro, 7892 422809, AK001379, Hs 121028, hypothetical protein FU10549, IQ,TM=M,SS=N, 7824
452203, X57522, Hε 352018, tranεporter 1, ATP-binding caεεette, sub, ABC_tran,ABC_membrane,SRP54,Thymιdylate_kιn,TM=Y,SS=M, 7823874755 431630, NM.002204, Hs 265829, integπn, alpha 3 (antigen CD49C, alpha , FG-GAP,Rhabd _glycop,ιntegπn A,TM=Y,SS=M, 7758985201 432874, W94322, Hs 279651, melanoma inhibitory xtivity, SH3,TM=M,SS=Y, 775887574 439453, BE264974, Hs 6566, thyroid hormone receptor interxtor 13, AAA,ABC_tran,CoaE,TM=M,SS=N, 7757751938 452747, BE153855, Hs 61460, Ig superfamily receptor LNIR, ig.Rhabd _glycop,TM=Y,SS=M, 7624 438089, W05391, Hs 351546, nuclear receptor subfamily 1, group I, , hormone rx.zf C4,none, 7605660377 427747, AW411425, Hs 180655, seππe/threonine kinase 12, pkιnase,TM=M,SS=N, 7578 430280, AA361258, Hs 237868, interleukin 7 receptor; frι3,none, 7476 429299, AI620463, Hs 347408, hypothetical protein MGC13102, none,TM=Y,SS=N, 7442528736 441384, AA447849, Hs 288660, retinoic xid induced 3, 7tm_3,none, 7442495127 446163, AA026880, Hs 25252, prolxtm receptor, none,NA,NA, 7436781609 414774, X02419, Hs 77274, plasminogen xtivator, urokinase, kπngle,trypsιn,planLthιonιns„ 7435897436
439237, AW408158, Hs 318893, ESTs, Weakly similar to A47582 B-cell gr, Fuππ-lιke,pkιnase,Rxep_L_domaιn,YLP,none, 7398360656 432636, AA340864, Hs 278562, claudin 7, PMP22_Claudιn,TM=Y,SS=M, 7394039735
431890, X17033, Hs 271986, integπn, alpha 2 (CD49B, alpha 2 subum, vwa,ιntegπn_A,FG-GAP,TM=Y,SS=M, 7383419689 416084, L16991, Hε 79006, deoxylhymidylate kinase (thymidylate k , none.none, 7382 436972, AA284679, Hs 25640, claudin 3, PMP22_Claudιn,TM=Y,SS=M, 7327160494
409799, D11928, Hε 76845, phosphoseπne phosphatase-like, Hydrolase,TM=M,SS=N, 7316
448569, BE382657, Hs 21486, signal transducer and xtivator of trans, SH2,STAT,STAT_bιnd,STAT_prot,TM=M,SS=N, 7315412186 428450, NM.014791, Hs 184339, KIAA0175gene product, KA1,pkmase,TM=M,SS=N, 72984375 422283, AW411307, Hs 114311, CDC45 (cell division cycle 45, S cerevis, CDC45,TM=M,SS=N, 728 451253, H48299, Hs 26126, claudin 10, PMP22 Claudιn,Peptιdase_M1,K_tetra,TM=Y,SS=M, 7256802721
416819, U77735, Hs 80205, pιm-2 oncogene, pkinase,, 7234455959
421817, AF146074, Hs 108660, ATP-binding cassette, sub-family C (CFTR, Fascιclιn,ABC_tran,ABC_membraπe,GTP EFTU,TM=M,SS=M, 7 162534435 451035, AU076785, Hs 430, plastin 1 (I isoform), efhand,CH,Adaptιn_N„ 7 145454546 424008, R02740, Hs 137555, putative chemokine rxeptoπ GTP-binding, 7tm_1,TM=Y,SS=M, 7126 414482, S57498, Hs 76252, endothelin rxeptor type A, 7tm_1,TM=Y,SS=M, 7 122413793
425003, AF119046, Hs 154149, apuπnic/apyπmidimc endonuclease(APEX , Troponm.Exo endo_phos,IQ,TM=M,SS=N, 7 106719368 430890, X54232, Hs 2699, glypican 1, Glypιcan,TM=M,SS=M, 7088937083 407792, AI077715, Hs 39384, putative sxreted ligand homologous to f, noπe,TM=M,SS=Y, 7052 426514, BE616633, Hs 170195, bone orphogenetic protein 7 (osteogemc, TGF-beta,TGFb_propeptιde„ 7042 431241, AA496799, Hs 36958, ESTs, SH2,RasGEF,πone, 703
437139, W73685, Hs 118513, ESTs, Weakly similar to RTA RAT PROBABLE, 7tm_1,TM=Y,SS=M, 703 420311, AW445044, Hs 38207, Human DNA sequence from clone RP4-530I15, none.none, 7026 439979, AW600291, Hs 6823, hypothetical protein FU10430, none,TM=M,SS=N, 7008 422846, BE513934, Hs 1583, neutrophil cytosolic fxtor 1 (47kD, chr, SH3,PX,TM=M,SS=N, 6991626794 416250, AA581386, Hs 73452, Kremen 2, kπngle CUB.WSC , 6972 430770, AA765694, Hs 123296, ESTs, none.none, 695
418869, AW516565, , gb xq01d05 x1 Soares.NHCeC.cervica! jumo, none,RasGAP,WW,IQ, 6948 428953, AA306610, Hs 348183, tumor nxrosis fxtorrxeptorsuperfami, 60s_πbosomal,Rιbosomal_L10,TNFR_c6,DEAD„ 6914
418283, S79895, Hs 83942, cathepsin K (pycnodysostoεis), Peptidase.CI „ 6 876190476
419667, AU077005, Hs 92208, a disintegnn and metalloproteinase doma, dιsιntegπn,Repralysιn,Pep_M12B_prapep,TM=M,SS=M, 6862970711 421143, AB024536, Hs 102171, immunoglobulin superfamily containing Ie, ig LRR LRRNT,LRRCT,TM=M,SS=M, 6849056604 456181, L36463, Hs 1030, ras inhibitor; RA,SH2,VPS9,TM=M,SS=N, 6762 436856, AI469355, Hs 127310, ESTs, pkιnase,rrm,TM=M,SS=N, 6721428571
411125, AA151647, Hs 68877, cytochrome b-245, alpha polypeptide, none,TM=Y,SS=M, 6720348837
439750, AL359053, Hs 57664, Homo sapiens mRNA full length insert cDN, IMPDH_C,IMPDH_N CBS ιntegπn_B,Rιcιn_B_lxtιn, 6717307692 450334, AF035959, Hs 24879, phosphatidic xid phosphatase type 2C, PAP2,TM=Y,SS=M, 6715240642 426437, BE076537, Hs 169895, ubiquitin-conjugatmg enzyme E2L 6, Armadιllo_seg,UQ_con,none, 6688194444 439738, BE246502, Hε 9598, εema domain, immunoglobulin domain (lg)„ Sema,PSI,ιntegnn_B,TM=Y,SS=N, 6670553936
428385, AF112213, Hs 184062, putative Rab5-ιnteractιng protein, SH2.SH3 , 6662921348 456534, X91195, Hs 100623, phospholipase C, beta 3, neighbor pseudo, LIM,PDZ,pkιnase„ 6653713299 425289, AW139342, Hs 155530, interferon, gamma-mducible protein 16, PAAD.DAPIN.HIN,, 6652671756 426500, NM.014638, Hs 170156, KIAA0450 gene product, C2,PI-PLC-Y,TM=M,SS=N, 6639655172 438113, AI467908, Hs 8882 ESTs, 7tm_1,noπe, 66
444783, AK001468, Hs 62180, anillin (Drasophila Scraps homolog), xt, PH.none, 66 408482, NM.000676, Hs 45743, adenosme A2b rxeptor, 7tm_1,TM=Y,SS=M, 6548148148
410290, AA402307, Hs 322844, hypothetical protein DKFZp564A176, Sema,PSI,TIG,ιntegπn_B,TM=Y,SS=M, 6532763533 414809, AI434699, Hs 77356, transferπn rxeptor (p90, CD71), PA,TM=Y,SS=N, 6526951673 426440, BE382756, Hs 169902, solute camerfamily 2 (facilitated glu, sugar_tr,TM=Y,SS=M, 6512704174
420039, NM 004605, Hε 376147, sulfotransferase family, cytosolic, 2B, , Sulfotranεfer,, 6496 423031, AI278995, Hs 374579, ESTs, none.none, 6447658402
421445, AA913059, Hs 104433, Homo sapiens, clone IMAGE 4054868, mRNA, lonJrans.KJetra asp, 6426666667 433933, AI754389, Hs 355397, Homo sapiens clone TCCCIA00164 mRNA sequ, none,NA,NA, 64 435094, AI560129, Hs 289008, EST, none.none, 6312
432106, N58323, Hs 269098, ESTs, Weakly similar to RETROVIRUS-RELAT, SH3,PDZ,Guanylate_kιn,none, 6276556777
427640, AF058293, Hs 180015, D-dopxhrome tautomerase, COX8,SHMT,MIF,GST_C,EF1G_domaιn,GST_N,S1,Fz,Fπzzled,calretιculιn,7tm_2,rrm,PAP_asε∞,TM=Y,SS=M,
6272727273 435232, NM.001262, Hε 4854, cyclm-dependent kinase inhibitor 2C (p1, ank,TM=M,SS=N, 6269720102 418203, X54942, Hs 83758, CDC28 protein kinase 2, CKS„ 6219081272
411263, BE297802, Hs 69360, kinesm like 6 (mitotic centromere-assx, kιnesιn,TM=M,SS=N, 619 409512, AW979187, Hs 293591, melanoma differentiation assxiated prot, DEAD,helιcase_C,CARD,TM=M,SS=N, 6 188888889 449230, BE613348, Hs 356392, melanoma cell adhesion molecule, ιg,ιsodh,Rιbosomal_L6,F-box,TM=Y,SS=M, 6 188046647 440006, AK000517, Hs 6844, NALP2 protein, PYRIN-Contaimng APAF1-lι, AAA,NB-ARC,PAAD_DAPIN,NA,NA, 6 15503876 450581, AF081513, Hs 25195, TGF-beta 4, TGF-beta,TGFb_propeptιde„ 6 152
432314, AA533447, Hs 285173, ESTs, Xlink.none, 6 123040752
418844, M62982, Hs 1200, arxhidonate 12-lιpoxygenase, lιpoxygenase,PLAT,TM=M,SS=N, 6 12 421733, AL119671, Hs 1420, fibroblast growth fxtor receptor 3 (xh, ιg,pkιnase,TM=Y,SS=M, 6095758355 422051, AW327546, Hε 111024, εolute camerfamily 25 (mitoehondnal , mιto_carr;TM=M,SS=N, 6089164786 452683, AI089575, Hs 374574, progesterone membrane binding protein, homeobox.none, 606284153 445537, AJ245671, Hs 12844, EGF-like-domam, multiple 6, EGF.MAM,, 605513308 444309, U83236, Hs 10803, calcium and integπn binding protein (DN, efhand,, 604015544
414166, AW888941, Hs 75789, N-myc downstream regulated, DEAD.helicase C,rrm,Ndr,Cys knot,TIL,vwa,vwc,vwd,IQ,Rlla,abhydrolase,TGF- beta,DUF139,TPR,DSPc,tsp_1,Rιbosomal_S21,rvp,TM=M,SS=N, 6009562842 438108, AI471795, Hs 287776, vanilloid receptor-related osmotically a, ank,ion_trans,TM=Y,SS=N, 6004 413869, NM.000878, Hs 75596, interleukin 2 receptor, beta, none,TM=Y,SS=M, 5984536083 405484, , , C3002124* gι|12737280|ref|XP_006682 2| k, none,, 5978964401
414907, X90725, Hs 77597, polo (Drosophιa)-lιke kinase, Rιbosomal_L37ae,pkιnaεe,POLO box,tRNA-εynL1b,dynamιπ,dynamιn 2,GED,bZIP,M„ 5978431373 419216, AU076718, Hε 164021, small inducible cytokine subfamily B (Cy, IL8„ 5976 414135, NM.004419, Hs 2128, dual specificity phosphatase 5, Rhodanese,DSPc,Y_phosphatase,TM=M,SS=N, 5969387755
411756, BE294350, Hs 71891, diεcoidin domain receptor family, member; pkmase,F5_F8 type_C,TM=Y,SS=M, 595184136 424291, AL120051, Hs 144700, ephπn-B1, Ephπn,TM=Y,SS=M, 5951550388 453459, BE047032, Hs 257789, ESTs, none.none, 595
456373, BE247706, Hs 86693, membrane-spanning 4-domaιns, subfamily A, none,TM=Y,SS=N, 5938 429359, W00482, Hs 2399, matnx metalloprotemase 14 (membrane-m, hemopexin.Peptidase M10,TM=M,SS=M, 5917857143 414703 BE243877, Hs 380063, ATPase, Na? transporting, beta 3 polypep, Na_K-ATPase,TM=Y,SS=M, 5910455487 448775, AB025237, Hs 388, nudix (nucleoside diphosphate linked oi, NUDIX,TM=M,SS=M, 5901886793 452239, AW379378, Hs 356289, protein tyrosine phosphatase, rxeptor t none.none, 5868362832 418345, AJ001696, Hs 241407, seπne (or cysteine) proteinase inhibito, serpιn,TM=Y,SS=M, 5842 452875, BE275760, Hs 30928, DNA segment on chromosome 19 (unique) 11, Euk_poπn,TM=M,SS=M, 5816363636 439625, AF086453, Hs 58611, ESTs, Fork_head,gly∞lytιc_enzy,Na_sulph_symp, 5811594203 447343, AA256641 , Hs 236894, ESTs, Highly similar to S02392 alpha-2-m, none.none, 581 422765, AW409701, Hs 1578, bxuloviral IAP repeat-containing 5 (sun BIR,TM=M,SS=N, 5806 415198, AW009480, Hs 943, natural killer cell transcπpt4, noπe,TM=M,SS=N, 5804137931 431941, AK000106, Hε 272227, Homo εapiens cDNA FU20099 fis, clone CO, pkιnase,Fuπn-lιke,Rxep_L_domaιn,noπe, 58 457001, J03258, Hs 2062, vitamin D (1,25- dihydroxyvitamin D3) re, hormone.rx.zf C4,Metallothιo_5,TM=M,SS=N, 5794 439335, AA742697, Hs 62492, NM.052863 Homo sapienε secretoglobin, fa, none,, 5778588808 439246, AI498072, Hs 351474, membrane-associated tyrosine- and threon, ank,pkιnase,UPF0073„ 5763492064 452461, N78223, Hs 108106, transcnption fxtor; zf-C3HC4,ubιquιtιn,PHD,YDG SRA,TM=M,SS=N, 5728 414883, AA926960, Hs 348669, CDC28 protein kmaεe 1, CKS„ 5714634146
424517, AI539443, Hε 137447, Homo εapiens cDNA FU12169 fis, clone MA, SH2,STAT,STAT_bιnd,STAT_prot,πoπe, 5701666667 419056, M89957, Hs 89575, CD79B antigen (immunoglobulin assxiated, ιg,ITAM,TM=Y,SS=M, 5692 432269, NM.002447, Hs 2942, mxrophage stimulating 1 receptor (c-met, pkmase,Sema,PSI,TIG,A4_EXTRA,TM=M SS=M, 5686 452696, AI826645, Hs 211534, ESTs, ArfGap,PH,ank,Guanylate_kιn,PDZ,SH3, 5683673469 411030, BE387193, Hs 67896, 7-60 protein, none,TM=M,SS=N, 5676767677
447131, NM.004585, Hs 17466, retinoic xid receptor responder (tazaro, none,TM=Y,SS=N, 5672977625 426227, U67058, Hs 154299, Human proteinase xtivated receptor-2 mR, 7tm_1,TM=Y,SS=M, 5666 407722, BE252241, Hs 38041, pyndoxal (pyπdox e, vitamin B6) kinaε, pfkB,TM=M,SS=N, 5655616943
Figure imgf000247_0001
431685, AW296135, Hs 267659, vav 3 oncogene, CH,DAG_PE-bmd,PH,RhoGEF,SH2,SH3,DC1,TM=M,SS=N, 5129476584 411190, AA306342, Hs 69171, protein kinase C-like 2, pkιπase,pkιnase_C,HR1,TM=M,SS=N, 5 121527778
433573, AF234887, Hs 57652, cadhenn, EGF LAG seven pass G-type rxe, 7tm_2,EGF,cadheπn,lammm_EGF,lammιn_G Trypanjlycop.GPS.HRM TM=Y,SS=M, 5 107438017 433662, W07162, Hs 150826, RAB25 RAB25, member RAS oncogene family, ras,ABC_tran,arf,TM=M,SS=M, 5 10251046 419493, AF001212, Hs 90744, proteasome (prosome, macropaiπ) 26S εubu, CDK5_xtιvator,PCI,none, 5095194085
411027, AF072099, Hε 67846, leuk∞yte immunoglobulin like rxeptor, , ιnosιtol_P,ιg,TM=M,SS=N, 5092 435243, AW292886, Hs 348932, hypothetical protein dJ4340143, IRF.none, 5092 434417, AL110157, Hs 3843, Homo εapienε mRNA, cDNA DKFZp586F2224 (f, DSPc,noπe, 5091922006 415323, BE269352 Hε 949, πeutrophil cytosolic fxtor 2 (65kD, chr; SH3,TPR,TM=M,SS=N, 5088932806 418629, BE247550, Hs 86859, growth fxtor receptor bound protein 7, SH2,PH,RA„ 5082840237 420030, BE503994, Hs 146233, KIAA0418 gene product, SH3,none, 5080645161 444065, AW449415, Hs 10260, Homo sapiens cDNA FU11341 fis, clone PL, SH3„ 5063953488 421677, H64092, Hε 38282, ESTε, A1pp,Armadιllo_seg,IBB, 5056 411165, NM 000169, Hs 69089, galxtosidase, alpha Melibiase,, 5054133858 428479, Y00272, Hs 334562, cell division cycle 2, G1 to S and G2 to, pkιπase,ICE_p10,ICE_p20,TM=M,SS=M, 5054
423883, AF250238, Hs 134514, ATP binding cassette sub-family A (ABC1, ABC_tran,photoRC,SRP54,Ca_channel_B,Pteπn_4a,TM=Y,SS=M, 5051724138 421917, AB028943, Hs 109445, KIAA1020 protein, BTB zf C2H2,PI3_PI4_kιnase,PI3Ka,TM=M,SS=N, 5051282051 422241, Y00062, Hs 170121, protein tyrosine phosphatase, rxeptor t, kιnesιn,fn3,Y_phosphatase,TM=M,SS=N, 5047311828 410026, AI912061, Hs 55016, hypothetical protein FU21935, none.none, 504674221 426395, BE151985, Hs 355669, hypothetical protein FU23316, pkmase.noπe, 5040298508
418054, NM.002318, Hs 83354, lysyl oxidase-like 2, SRCR Lysyl_oxιdase,TM=M,SS=M, 5039039039 444895, AI674383, Hs 22891 , solute earner family 7 (cationic am o , ASC,deafh,TNFR c6, 5037151703 413472, BE242870, Hs 75379, solute camerfamily 1 (glial high affi, SDF,TM=Y,SS=M, 5034 446272, BE268912, Hs 14601, hematopoietic cell-spxific Lyn εubstrat, SH3,HS1_rep,TM=M,SS=N, 503030303 410772, BE275297, Hε 194685, Homo sapiens clone 24675 mRNA sequence, Topoιsom_bx,Topnm„ 5027985075
418613, AA744529, Hs 86575, mitogeπ xtivated protein kinase kinase , pkιnase,CNH,TM=M,SS=N, 5014652015 415166, NM.003652, Hs 78068, carboxypeptidase Z, Zn_carbOpept,Dιoxygenase,Fz„ 5012269939 416498, U33632, Hs 79351, potasεium channel, subfamily K, member 1, ιon_trans,TM=Y,SS=M, 5001811594 410687, U24389, Hs 65436, lysyl oxidase like 1 , LysyLoxidase,, 4997983871 430024, AI808780, Hs 227730, integnn, alpha 6, ιntegnn_A,FG-GAP,TM=Y,SS=M, 4994871795
409220, BE243323, Hs 51233, tumor nxrosiε fxtor rxeptor superfami, TNFR_c6,death,Lιpoproteιn_5,TIL,TM=Y,SS=M, 4987135506 423804, AW403448, Hs 1706, interferan-stimulated transcnption fxt, IRF,zf-C3HC4,IBR,zf-RanBP,TM=M,SS=N, 4985185185 423011, NM 000683, Hs 123022, adrenergic, alpha-2C-, rxeptoπ 7tm_1,TM=Y,SS=M, 4984 419577, L36531, Hε 91296, integπn, alpha 8, ιntegπn_A,FG-GAP,TM=Y,SS=N, 4968 402328, , , Target Exon, pkιnase,TM=M,SS=N, 496728972
421242, AW161386, Hs 13561, hypothetical protein MGC4692, πone,NA,NA, 4966334165 435523, T62849, Hs 11090, membrane-spanning 4-domaιns, subfamily A, πone,TM=Y,SS=M, 4964491363 414203, BE262170, Hs 78629, ATPase, a' transporting, beta 1 polypep, none.none, 4961956522 409582, R27430, Hs 271565, ESTs, none.Neur chan.LBD.Neur.chan me b, 4946 451292, AB037716, Hs 26204, KIAA1295 protein, SH3,TM=M,SS=N, 4943181818
453449, W16752, Hε 32981, sema domain, immunoglobulin domain (lg)„ ιg,Sema,PSI„ 4930508475 425233, Z17861, Hs 155218, E1B 55kDa-asεxιated protein 5, SPRY,SAP,pkmaεe,fn3,ιg, 4925347222 425247, NM 005940, Hs 155324, matnx metalloprotemase 11 (stromelysin, hemopexm,Peptιdase_M10„ 492 422282, AF019225, Hs 114309, apolipoprotein L, MotA_ExbB,TM=Y,SS=M, 4912181303 442572, AI001922, Hs 135121, hypothetical protein FU22415, none,HSP70, 4910224439
425743, BE396495, Hs 159428, BCL2-aεsxιated X protein, Bcl-2,TM=Y,SS=N, 4909972299 449523, NM.000579, Hs 54443, chemokine (C-C motif) receptor 5, 7tm_1,TM=Y,SS=M, 4904
409213, U61412, Hs 51133, PTK6 protein tyrosine kinase 6, SH2,SH3,pkιnase,TM=M,SS=N, 4897338403
411770, NM_014278, Hs 71992, heatshxk proteιn (hsp110 famιly), HSP70,TM=M,SS=N, 4894 446872, X97058, Hs 16362, pyπmidinergic rxeptor P2Y, G-pratem c, 7tm_1 ,TM=Y,SS=M, 4886
423198, M81933, Hs 1634, cell division cycle 25A, Rhodanese.none, 4884
445462, AA378776, Hs 288649, hypothetical protein MGC3077, none,, 4876379691
448153, Y10805, Hs 20521, HMT1 (hnRNP methyltransferase, S cerevi, NusG,, 4876117497
427792, M63928, Hε 180841, tumor nxroεiε factor rxeptor superfami, SRP14,TNFR_c6„ 4873684211 449027, AJ271216, Hε 22880, dipeptidylpeptidaεe III, Peptιdase_M49,EGF,ig,Neuregulιn,TM=M,SS=N, 4872641509
421541, NM.003942, Hs 105584, nbosomal protein S6 kinaεe, 90kD, polyp, pkιnase,pkιnase_C,TM=M,SS=N, 4869318182
429619, AL120751 , Hs 211568, eukaryotic translation initiation factor; none.none, 4868073879
458873, AW150717, Hs 345728, STAT induced STAT inhibitor 3, none.none, 4861538462
437669, AI358105, Hs 123164, ESTε, Weakly similar to match to ESTs AA, noπe,pkιnase,pkιnase_C, 4854651163 405545, , , Target Exon, ABC tran,SRP54,ABC_membrane,TM=Y,SS=M, 485
424779, AL046851, Hs 153053, CD37 antigen, transmembrane4,TM=Y,SS=M, 4848387097
424263, M77640, Hs 1757, L1 cell adhesion molxule (hydrocephalus, fn3,ιg,IRK,TM=Y,SS=M, 4846153846
425421, L11669, Hs 157145, tetr ycline transporter-like protein, sugar_tr,TM=Y,SS=M, 4843694494
421267, BE314724, Hε 103081, πboεomal protein S6 kinase, 70kD, polyp, pkιπase,pkιnase_C,TM=M,SS=N, 4842532468 418736, T18979, Hs 87908, Snf2-related CBP xtivator protein, helicase C,AT_hook,SNF2_N,TM=M,SS=N, 4842
444143, AW747996, Hε 160999, ESTε, Moderately similarto A56194 throm, Bcl-2,none, 4841071429
417331, AW411297, Hs 81972, SHC (Sro homology 2 domain-containing) t, SH2,PID,zf C2H2,SCAN,AMP-bιπdιng,KRAB,TM=M,SS=N, 4839464883
422010, AA302049, Hs 31181, Homo sapiens cDNA. FU23230 fis, clone C, none,SDF,sugar_tr; 4837837838
434521, NM 002267, Hs 3886, karyophenn alpha 3 (importin alpha 4), Armadillo seg,IBB,TM=M,SS=N, 4833333333 450447, AF212223, Hs 25010, hypothetical protein P15-2, NTF2,TM=M,SS=N, 4821666667
453082, H18835, Hs 31608, hypothetical protein FU20041, ιon_trans,TM=Y,SS=M, 4820936639
417949, AL049795, Hs 83004, interieukin 14, πone,Armadιllo_seg,IBB,WD40, 481443299
439569, AW602166, Hs 222399, CEGP1 protein, EGF.TNFR c6 granulin.CUB.Keratin B2,TIL,TM=M,SS=M, 481
432581, AU076465, Hs 278441, KIAA0015 gene product PP2C,TM=M,SS=N, 4805063291 432194, AL040801, Hs 273219, breast cancer anti-estrogen resiεtance 1, SH3„ 4803191489
431472, AK001023, Hε 256549, nucleotide binding protein 2 (E coli Mm, fer4_NιfH,ParA,APS_kιnase ArsA_ATPase,TM=M,SS=N, 4800990099
450690, AA296696, Hs 333418, FXYD domain-containing ion transport reg, ATP1G1 PLM_MAT8,TM=Y,SS=M, 4795480881
448950, AF288687, Hs 9275, CGI-152 protein, E1-E2_ATPase,Hydrolase,TM=Y,SS=N, 4776923077
427681 , AB018263, Hε 284232, tumor nxrosis fxtor rxeptor superfami, death,TNFR.c6,PH,Xlιnk,RhoGEF,Metallothιo_5,TM=M,SS=M, 4772196262 432827, Z68128, Hs 3108, Rho GTPase xtivating protein 4, FCH,RhoGAP,SH3,TM=M,SS=N, 4760115607
433376, AI249361, Hs 74122, caspase 4, apoptosis related cysteine pπ CARD,ICE_p10,ICE_p20„ 4751162791
419981, AA897581, Hs 128773, ESTs, pkιnase,DAG_PE-bιnd,pkιnase_C,OPR,none, 4748
431657, AI345227, Hs 105448, ESTs, Weakly similarto B34087 hypotheti, pkιnxe,PA28_alpha,PA28_beta,Cu_amιne_oxιd,Cu_amιne_oxιdN2,Cu_amιne_oxιdN3, 4746 412958, BE391579, Hs 75087, Fas-xtivated seπne/threonine kinase, none,, 4736781609 414443, AU077268, Hs 76144, platelet-deπved growth fxtor rxeptor,, ιg,pkιnase,TM=Y,SS=N, 4733 419250, AW770185, Hs 356066, U5 snRNP-spxific protein, 116 kD, 7tm_1,BAH,zf CXXC,DNA_methylase, 4725454546 417903, NM.002342, Hs 1116, lymphotoxin beta rxeptor (TNFR εuperfam, TNFR_c6,TM=M SS=M, 4718858132 414368, W70171, Hs 75939, undine monophosphate kinase, PRK.CoaE,, 4718836565
426059, BE292842, Hs 166120, interferon regulatory fxtor 7, IRF„ 4718543046 414788, X78342, Hs 77313, cyclm-dependent kinase (CDC2 like) 10, pkιnase,TM=M,SS=N, 4708 407601, AC002300, Hε 37129, sodium channel, nonvoltage gated 1, beta ASC,TM=Y,SS=M, 4707920792 448520, AB002367, Hs 21355, doublxortin and CaM kinase like 1, pkιnase,DCX,TM=M,SS=N, 4707671958 407143, C14076, Hs 332329, EST, πone,TM=Y,SS=M, 4682675815
428582, BE336699, Hs 185055, BENE protein, none,TM=Y,SS=M, 4681818182
408806, AW847814, Hs 75608, Homo sapienε cDNA FU21532 fis, clone C, SH3,PDZ,Guanylate_km none, 4680440771 448133, AA723157, Hs 73769, folate rxeptor 1 (adult), Folate_rx,MIP,TM=M,SS=M, 4679841897 418836, AI655499, Hs 161712, ESTs, pkinase,Activm_recp,PDZ,ZU5,death, 4679180887 425308, M97639, Hs 165585, rxeptor tyrosine kinase like orphan rx, ιg,kπngle,pkιnaεe,Fz,TM=Y,SS=M, 4675342466
414665, AA160873, Hs 356307, serum amyloid A1, zf-C2H2,BTB,K_tetra,none 467447496 449843, R85337, Hs 24030, solute earner family 31 (copper transpo, none,TM=Y,SS=M, 4673701299 428245, AF151048, Hε 183180, anaphaεe promoting complex subunit 11 (y, none,, 4656756757 417088, M54915, Hs 81170, pιm-1 oncogene, pkιnase,TM=M,SS=N, 4656190476 420340, NM.000734, Hs 97087, CD3Z antigen, zeta polypeptide (TιT3 com, ITAM,TM=M SS=M, 465 425966, NM.001761, Hs 1973, cyclin F, cyclιn,F-box cyclιn_C,TM=M,SS=N, 4644 417929, R27219, Hs 74647, Human T-cell rxeptor xtive alpha-chain, ig.abhydrolase, 4640384615 430603, AA148164, Hs 247280, HBV assxiated fxtoπ zf C3HC4,zf-RanBP,pkmase, 4630653266 419273, BE271180, Hs 293490, ESTs, Weakly similarto I38022 hypotheti, none.none, 4628 453880, AI803166, Hs 135121, ESTs, Weakly similar to I38022 hypotheti, HSP70,noπe, 4619047619
459399, BE407712, Hs 153988, creatine kinase, mitxhondnal 1 (ubiqui, none.none, 4618577075 412970, AB026436, Hs 177534, dual spxificity phosphatase 10, Rhodanese.DSPc,, 4616 433577, AW007080, Hs 284192, ESTs, none.none, 4614 444838, AV651680, Hs 208558, ESTs, ιntegnn_A,FG-GAP,none, 4612149533 408369, R38438, Hs 118747, SLC15A2 Solute earner family 15 (H+/pep, PTR2,TM=Y,SS=N, 4602
450825, AC005954, Hs 25527, tight junction protein 3 (zona ∞cludeπs, PDZ,Guanylate_kιn„ 4596875 443951, F13272, Hs 356835, ferntiπ, light polypeptide, PMP22_Claudιn,none, 4587931035 433083, AL042759, Hs 191762, ESTs, SH3,PX,TM=M SS=N, 4586
407239, AA076350, Hs 67846, leukocyte immunoglobulin like receptor, , ιg,TM=Y,SS=M, 458557047 412926, AI879076, Hs 75061 , mxrophage myπstoylated alanine rich C , MARCKS,, 4579087049
422009, AI742845, Hs 110713, DEK oncogene (DNA binding), SAP,, 4576347305 412584, X54870, Hs 74085, DNA segment on chromosome 12 (unique) 24, noπe.tectin.c, 457312253 414561, AI064813, Hs 195155, Homo sapiens ammo xid transport system, Aa_trans,TM=Y,SS=N, 4573015873
422627, BE336857, Hε 118787, transforming growth fxtor, beta-induced, Fascιclιn,ABC_tran ABC.membrane,GTP_EFTU,TM=M,SS=M, 4570526316 459053, AI807052, Hs 97792, ESTs, none,7tm_2,GPS, 4569230769
424247, X14008, Hs 234734, lysozyme (renal amyloidosiε), lys,ιg,FAD_Synth,ldh,ldh_C,pkιnase„ 4566195373 439975, AW328081, Hs 6817, inosine tπphosphataεe (nucleoside tπph, Ham1p_lιke,TM=M,SS=N, 456056338 416178, AI808527, Hs 192822, serologically defined breaεt cancer and, none,TM=M,SS=N, 4658 408051, AI623351, Hε 172148, ESTs, PH.RhoGAP.πone, 4552307692 421846, AA017707, Hs 1432, protein kinase C substrate 80K-H, efhand.ldl.recepLa,, 4547761194
439659, AW970780, Hs 59483, leucine-πch repeat-containing G protein, 7tm_1,LRR,TM=Y,SS=N, 4547169811
426201, AW182614, Hs 128499, ESTε, SH3,none, 4541666667
424905, NM.002497, Hs 153704, NIMA (never in mitosis gene a) related k, pkιnase,TM=M,SS=N, 4536
445229, BE276013, Hε 343828, Homo sapiens mRNA for FU00086 protein, , G-alpha,TM=M,SS=N, 4530588235 413109, AW389845, Hs 110855, ESTs, PH04,none, 4529761905
426125, X87241, Hs 166994, FAT tumor suppresεor (Drasophila) homolo, EGF,cadheπn,lamιnιn_G,TM=Y,SS=M, 4529710145
402330, , , Target Exon, pk ase.none, 4528070175
439238, N47305, Hs 302161, EDG-8 (endothelial differentiation, sph, 7tm_1,TM=Y,SS=M, 4524
433437, U20536, Hs 3280, caspase 6, apoptosiε-related cyεteine pπ ICE_p10,ICE_p20„ 4523715415 413781, J05272, Hs 850, IMP (inosine monophosphate) dehydrogenas, CBS,IMPDH_C,IMPDH_N,NPD,TM=M,SS=N, 4522900763
431429, AF072813, Hs 252831, reticulon 3, Retιculon,Fz,ιg,knngle,pkιnaεe,TM=Y,SS=N, 4512
424078, AB006625, Hs 139033, paternally expreεsed 3, zf-C2H2,KRAB,none, 4512
420602, AF060877, Hs 99236, regulator of G-protein signalling 20, RGS,TM=M,SS=N, 451
449101, AA205847, Hs 23016, G protein-coupled rxeptor, 7tm 1,TM=Y,SS=M, 4506 408157, AA047685, Hs 62946, ESTs, noπe.pkinase, 4504
446291, BE397753, Hs 14623, interferon, gamma-inducible protein 30, GILT,TM=M,SS=Y, 450215208
431326, AW970580, Hs 198689, KIAA0728 protein, none.none, 4501
428072, BE258602, Hs 182366, heat shxk protein 75, HATPase c,HSP90,TM=M,SS=N, 448828125
415149, X12451, Hs 78056, cathepsin L, Peptιdase C1„ 4484375 421959, AW751497, Hs 98370, cytochrome P450, subfamily IIS, polypept, p450,TM=Y,SS=M, 448
445143, U29171, Hs 378918, casein kinase 1, delta, zf-C3HC4,Fιlamιn,zf-B box,NHL,pkιπase,zf-MIZ,TM=M,SS=N, 4478092784
421071, AI311238, Hs 104476, ESTs, Weakly similar to CGHU1E collagen , πone,TM=Y,SS=M, 4477337111
410590, BE615216, Hs 64746, chloπde intracellular channel 3, none,TM=M,SS=N, 4476
438774, AA431620, Hs 379034, hypothetical protein MGC2745, none,none, 4474874372 410726, AI623859, Hs 15936, ESTs, pkιnase,pro_ιsomerase,none, 447
429903, AL134197, Hs 93597, cyclm-dependent kinase 5, regulatory su, CDK5_xtιvator,none, 4468
426485, NM.006207, Hs 170040, platelet-deπved growth fxtor rxeptor-, ιg„ 4464944649
433646, AA603319, Hs 155195, ESTs, pou,homeobox,lιg_chan,ANF_receptoπ 4458
410293, AK000047, Hs 61960, hypothetical protein, K_telra,TM=M,SS=N, 4453020134 453464, AI884911, Hs 32989, rxeptor (calcitonin) activity modifying, πone,TM=Y,SS=N, 4448198198
410583, AW770280, Hs 36258, ESTs, Moderately similar to JC5238 galx, SH3,PDZ,Guanylate_kιn,none, 4446927374
441455, AJ271671, Hs 7854, zinc/iron regulated transporter-like, Zιp,TM=Y,SS=M, 4445010183
453064, R40334, Hs 89463, potassium large conductance calcium-xti, none.none, 4436480187
443303, U67319, Hs 9216, caspase 7, apoptosis-related cysteine pπ pkιnaεe,ICE_p10,ICE_p20,TM=M,SS=M, 4433411215 411825, AK000334, Hε 352415, εolute earner family 39 (zinc transport, SNF,Zιp,TM=Y,SS=N, 4432765152
428376, AF119665, Hs 184011, pyrophosphatase (inorganic), Pyrophosphatase,TM=M,SS=N, 4428571429
429592, AB029041, Hs 209646, KIAA1118 protein, Tropoπin.Exo endo_phos,IQ,TM=M,SS=N, 4428
419344, U94905, Hs 277445, dixylglycerol kinase, zeta (104kD), ank,DAGKa,DAGKc,DAG_PE-bιnd,TM=M,SS=N, 4426229508 427138, N77624, Hs 173717, phosphatidic xid phosphatase type 2B, PAP2,noπe, 44234375 414496, W73853, Hs 355424, ESTs, pkιnase,F5_F8_type_C,adh_short,none, 442114094 429432, AI678059, Hε 202676, synaptonemal complex protein 2, none,TM=M,SS=N, 442 429922, Z97630, Hs 226117, H1 histone family, member 0, lιnker_hιstone,TM=M,SS=N, 4419207317 446700, AW206257, Hs 156326, Human DNAεequencefrom clone RP11-145L2, none,TM=M,SS=N, 4418181818
435411, AW444619, Hs 138211, ESTs, none.pkinase, 4414
414581, AA256213, Hs 72010, ESTs, none,Carn_xyltraπsf,Cholιne_kιnase,SC01-SenC,Glycos_transf_3,Gly∞s_trans_3N, 441 418558 AW082266, Hs 86131, Fas (TNFRSF6)-ass∞ιated via death domai, death.DED,, 4408523909 442259, AI690269, Hs 201345, ESTs, Acetyltransf,RhoGAP,FCH,SH3,Kelch,fn3, 4406 415860, D56051, Hs 78888, diazepam binding inhibitor (GABA rxepto, ACBP,TM=M SS=N, 4404678363
434419, AL040606, Hs 296938, dual spxificity phosphatase 7, DSPc,TM=M,SS=N, 4404 404440, , , NM 021048 Homo sapienε melanoma antigen,, MAGE,TM=M,SS=N, 44 435542, AA687376, Hε 351226, ESTε, SH3,ιg,pkmaεe,PH,spxtrιn,RhoGEF,none, 4394 413367, NM.006517, Hs 75317, solute earner family 16 (monxarboxylic, sugar_tπTM=Y,SS=N, 439028777 435732, AF229178, Hε 123136, leucine πch repeat and death domain con, none.none, 438490566
427359, AW020782 Hs 79881, Homo sapiens cDNA FU23006 fis, clone L, 7tm_1,none, 4382129278 425749, AW328587, Hs 159448, surfeit 2, none , 4382
417874, BE616160, Hs 82829, pratem tyrosine phosphatase, non rxept, Y_phosphatase,TM=Y,SS=N, 4381422925 414806, D14694, Hs 77329, phosphatidylseπne synthase 1, PSS,TM=Y,SS=M, 4380681818 431837, T79326, Hs 331967, olfactory rxeptor, family 2, subfamil , none,7tm_3,suεhι,ANF_receptoπ 4376
417115, AW952792, Hs 334612, small nuclear ribonucleopratein polypept Sm.pkmase,, 4370247934 434876, AF160477, Hs 61460, Ig εuperfamily receptor LNIR, ιg,Rhabd_glycop,TM=Y,SS=M, 437 430379, AF134149, Hs 240395, potassium channel, subfamily K, member 6, ion trans,TM=Y,SS=M, 4367777778 403912, , , C5000394* gι|12737280|ref|XP_0066822| k, none,TM=M,SS=N, 4367684478 426268, AF083420, Hs 168913, seπne/threomne kinase 24 (Ste20, yeast, pkinase,, 4366348449
434263, N34895, Hs 79187, ESTs, ig.none, 4358527132 404760, , , Target Exon, cadheπn,TM=M,SS=M, 4356
413076, U10564, Hs 75188, weel (S pombe) homolog, pkιnase,TM=M,SS=N, 435472973
420757, X78592, Hs 99915, androgen rxeptor (dihydrotestosterone r, hormone rec.zf C4,Androgen_rxep,TM=M,SS=N, 4354 426812, AF105365, Hε 172613, solute earner family 12 (potassium/chlo, noπe,TM=Y,SS=N, 4353244838
431674, AA098901, Hs 301642, G-protem coupled rxeptoπ none.GCV.H, 435 431886, L77964, Hs 271980, mitogen xtivated protein kinase 6, pkιnase,TM=M,SS=N, 4347893916 447719, BE387402, Hs 19333, hypothetical protein FU10349 adenylatekιnase,ATP-bιnd,TM=M,SS=N, 4346007605 424837, BE276113, Hs 333034, N xetyltransferase, homolog of S cerev, Acetyltransf,TM=M,SS=N, 4344 449437, AI702038, Hs 100057, Homo εapiens cDNA FU22902 fis, clone K, none.none, 4334722222
411768, NM.013371, Hs 71979, interleukin 19, IL10„ 4322
445350, AF052112, Hs 12540, lysophospholipase I, abhydrolase_2,TM=M,SS=N, 4320359281 425964, AW889928, Hs 9071, progesterone membrane binding protein, hom∞box.none, 4318867925 450998, BE387614, Hs 25797, splicing fxtor 3b, subunit 4, 49kD, rrm,TM=M,SS=N, 4316573557 408908, BE296227, Hs 250822, seπne/threonme kinaεe 15, pkinase,, 4316
400290, H18836, Hs 31608, hypothetical protein FU20041, none.Cys.knot, 4314728682 438899, AF085833, Hs 135624, ESTε, none,PI3_PI4_kιnase,PI3Ka,PI3K_C2,PI3K_rbd,PI3Kj>85B, 4314084507 418883, BE387036, Hs 1211, xid phosphatase 5, tartrate resistant, Metallophos,TM=M,SS=M, 4312121212 419607, R52557, Hs 91579, Homo εapienε clone 23783 mRNA εequeπce, IMP4,TM=M,SS=N, 4304407714 421532, AW138207, Hs 146170, hypothetical protein FU22969, Armadιllo_seg,HEAT,TM=M,SS=N, 4304
430017, AA263172, Hε 35, protein tyrosine phosphatase, non-recept, Y_phosphatase,TM=M,SS=M, 4302 447224, BE617125, Hε 142076, gb 601441664F1 NIH MGC 65 Homo εapiens c, none.NA.NA, 4302 425424, NM 004954, Hs 157199, ELKL motif kinase, pkιnase,UBA,KA1,TM=M,SS=N, 4301639344 454042, H22570, Hε 47860, hypothetical protein FU20093, ιg,pkιnaεe,LRR,LRRNT,LRRCT,none, 430141844 446143, BE245342, Hε 306079, εx61 homolog, NUDIX,εxY,E1_dehydrog,transkeLpyπTM=Y,SS=M, 4300872093
428981, BE313077, Hs 93135, ESTs, Weakly similar to ALU2.HUMAN ALU S, none.rrm, 4292620865 432562, BE531048, Hs 278422, DKFZP586G1122 protein, zf-C2H2,TM=M,SS=N, 4290258449 432945, AL043683, Hs 8173, hypothetical protein FU10803, πoπe,TM=M,SS=M, 4288405797
421921 , H83363, Hs 355993, transl∞aεe of inner mitxhondπal membπ zf-Tιm10_DDP,efhand,CH,8pxtnn,serpιn,TM=M,SS=N, 4284 448564, AL044962, Hs 21453, mositol 1 ,4,5-tπsphosphate 3-kιnase C, IPK,, 428057554
453941, U39817, Hs 36820, Bloom syndrome, DEAD,helιcase_C,HRDC,TM=M,SS=N, 428
437712, X04588, Hε 85844, neurotrophic tyroεine kinaεe, receptor, , Tropomyosιn,pkιnase,LRR,LRRCT,Hydantoιnase B.Hydantomase A,TM=M,SS=N, 4277477478 417426, NM.002291, Hs 82124, laminin, beta 1, lammιn_EGF,lamιnιn_Nterm,ιntegπn.B„ 4276162791 450296, AL041949, Hs 24756, hepatocyte growth fxtor-regulated tyros, none.none, 4273927393 438012, AA393254, Hs 43619, ESTs, Armadillo seg.none, 4273134328
409619, AK001015, Hs 55220, BCL2-ass∞ιated athanogene 2, BAG,TM=M,SS=N, 4273109244
418529, AW005695, Hs 250897, TRK-fused gene, Band 41,ERM,pkιnase,LRR,LRRCT,MAM,Nucleoplxmιπ,Trapomyoειn,OPR,filament,bZIP,G-gamma,M DUF164,TM=M,SS=N,
4272123894 415214, AI445236, Hε 125124, EphB2, fn3,pkιnase,SAM,EPH_lbd,TM=Y,SS=M, 4268 438233, W52448, Hs 56147, ESTs, Neur chan LBD.Neur chan.memb.MAGE, 426284585
429019, AA443280, Hs 279907, myosin IIIA, myosιn_head,pkιnase,PRK,IQ,TM=M,SS=N, 4262 424959, NM.005781, Hs 153937, xtivated p21cdc42Hs kinase, ldh,ldh_C,SH3,pkιnase,UBA,TM=M,SS=N, 4258695652 453655, AW960427, Hε 342874, tranεformmg growth fxtor, beta rxepto, zona_pellucιda,none, 4257208766 417414, AA434589, Hs 367676, dUTP pyrophosphatase, dUTPase.KRAB,, 4251785714 453905, NM.002314, Hs 36566, UM domain kinase 1, pkιnase,LlM,PDZ,zf PARP,TM=M,SS=N, 4249116608
424232, AB015982, Hs 143460, protein kinase C, nu, pkιnase,DAG_PE-bιnd,PH,TM=M,SS=N, 4247692308 404883, , , ENSP00000216009 Sodium-glucose cotranspo, SSF,TM=Y,SS=M, 4242424242 412507, L36645, Hs 73964, EphA4, frι3,pkmase,SAM,EPH lbd,TM=Y,SS=M, 4239285714 411089, AA456454, Hs 355702, cell division cycle 2 like 1 (PITSLRE pπ none.none, 4237313433 436957, AA902488, Hs 122952, ESTs, πone,DAGKc,DAGKa,RA,DAG_PE-bιnd, 4236
452568, AA805634, Hs 300870, Homo sapienε mRNA, cDNA DKFZp547M072 (fr, PI3_PI4_kιπase,TM=M,SS=M, 423537415 433535, AF111106, Hs 3382, protein phosphatase 4, regulatory subuπi, HEAT,TM=M,SS=N, 4234793187 432728, NM.006979, Hε 278721, HLA class II region expressed gene KE4, Zιp,lιg_chan,TM=Y,SS=M, 4234545455 416350, AF188625, Hs 189507, phospholipase A2, group HD, phostιp,TM=M,SS=Y, 4234 409533, AW969543, Hs 144609, mitogen xtivated protein kinase kinase , Peptιdase_C48,none, 4230666667
427127, AW802282, Hs 22265, pyruvate dehydrogenase phosphatase, PP2C,none, 4228009259 403362, , , NM.001615* Homo sapienε xtin, gamma 2, , xtιn„ 422688478 417866, AW067903, Hs 82772, collagen, type XI, alpha 1, Collagen,COLFI,TSPN,lammιn_G,CorA„ 4226388889 428897, AJ245719, Hs 194385, hypothetical protein FLJ20234, SH2,TM=M,SS=N, 4224731183
425771, BE561776, Hs 159494, Bruton agammaglobulinemia tyrosine kinas, SH2,SH3,pkιπase,PH,BTK,TM=M,SS=N, 4223684211
418566, C21220, Hs 321717, hypothetical protein FLJ10875, zf-C2H2,BTB,K_tetra 7tm_1, 4222807018
454098, W27953, Hs 217493, Plakophilin, none.none, 422 424381, AA285249, Hs 146329, protein kinase Chk2 (CHEK2), pkιnase,FHA,DnaJ,TM=M,SS=N, 421875
419223, X60111, Hs 1244, CD9 antigen (p24), transmembrane4,TM=Y,SS=M, 4217130215
436756, Z18364, Hs 198298, v-src avian εarcoma (Schmidt-Ruppin A-2), none.none, 4216
450167, AA446404, Hε 24563, NTF2-related export protein 1, NTF2,TM=M,SS=N, 4215163934
416224, NM.002902, Hs 79088, reticulocalbin 2, EF-hand calcium b din, ethand,, 4212041885 432539, AL138169, Hs 278378, karyopheπn beta 2b, transportin, none,DS,UPF0139,Glyco_hydra_38, 4207407407
416661, AA634543, Hs 79440, IGF-II mRNA-bindiπg protein 3, KH-dcmaιn,rrm,TM=M,SS=N, 4206
432284, AA532807, Hs 287740, ESTs, pkmase.none, 4205454546
418758, AW959311, Hs 172012, hypothetical protein DKFZp434J037, pkιπaεe,RI01,TM=M,SS=N, 4204142012
450056, BE047394, Hε 502, ESTs, Weakly similar to S71512 hypotheti, ABC_tran,ABC_membrane,ιg,MHCJI_beta,SRP54,prateasome,ABC_membraπe,ABC_traπ, 4202572347 412817, AL037159, Hs 74619, proteasome (prosome, mxropain) 26S subu, PC_rep,TM=M,SS=N, 4202061856
425394, AA356730, Hε 323949, kangai 1 (suppression of tumoπgenicity , tranεmembrane4,none, 4 195014663
449335, AW150717, Hs 345728, STAT induced STAT inhibitor 3, SH2,TM=M,SS=N, 4192248062
415023, AA932146, Hs 355397, Homo sapiens clone TCCCIA00164 mRNA εequ, none,NA,NA, 4 192
443907, AU076484, Hε 9963, TYRO protein tyroεine kinase binding pro, none,TM=M,SS=Y, 4 191878981 445330, R52656, Hs 21691, ESTs, 7tm_1,none, 4 189922481
430016, NM 004736, Hs 227656, xenotrapic and polytrapic retrovirus rx, SPX,EXS,TM=Y,SS=N, 4 188333333
434633, AI189587, Hs 120915, ESTs, SH3,PH,RhoGAP,πone, 4 187106918
452908, AB001451, Hs 30965, neuronal She adaptor homolog, SH2,PID,Zn_carbOpept,TM=M,SS=N, 4 186885246
439318, AW837046, Hε 6527, G protein-coupled receptor 56, 7tm_2,CytC_asm,GPS,TM=Y,SS=M, 3930957684 432201, AI538613, Hs 298241, Transmembrane protease, senne 3, ldl_rxepLa,trypsιn,TM=Y,SS=M, 3893103448
428969, AF120274, Hs 194689, artemin, TGF-beta„ 3884030418
444633, AF111713, Hs 12284, junctional adhesion molxule 1, ιg,TM=Y,SS=M, 3831669044
432305, M62402, Hs 274313, insulin-like growth factor binding prate, thyroglobulιn_1,IGFBP,A2M_N,TM=M,SS-N, 3742996346
405547, , , NM.018833* Homo sapiens transporter 2, A, ABC_tran,SRP54,ABC_membrane,TM=Y,SS=M, 3676 407853, AA336797, Hs 40499, diekkopf (Xenopus laevis) homolog 1 , πone,TM=M,SS=Y, 3634
426427, M86699, Hs 169840, TTK protein kinaεe, pkinase,, 3562
427585, D31152, Hs 179729, collagen, type X, alpha 1 (Schmid metaph, C1q,Collagen„ 349
405546, , , NM.018833* Homo sapiens transporter 2, A, ABC_tran,SRP54,ABC_membrane,TM=Y,SS=M, 3422661871
439820, AL360204, Hs 283853, Homo sapiens mRNA full length insert cDN, none.none, 3402 404210, , , NM.005936 Homo sapiens myeloid/lymphoid , FHA,PDZ,RA,DIL,TM=M,SS=N, 3368807339
424522, AL134847, Hs 149957, πboεomal protein S6 kinase, 90kD, polyp, pkιnase,pkιnaεe_C„ 3 213402062
418678, NM 001327, Hs 87225, cancer/teεtiε antigen (NY-ESO-1), none,TM=M,SS=N, 3084
451106, BE382701, Hε 25960, N-MYC oncogene, HLH,Myc_N_term,TM=M,SS=N, 1 55 TABLE 17B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Acceεsion Genbank xceεsion numbers
Pkey CAT Number Accession
418869 12789.14 AA229762 AA230035
TABLE 17C
Pkey Unique number correεponding to an Eoε probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entiled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted.
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLpoεition
402075 8117407 Pluε 121907-122035,122804-122921,124019-12416
401781 7249190 Minus 83215-83435,83531-83656,83740-83901 ,8423
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
405932 7767812 Minus 123525-123713
400517 9796686 Minus 49996-50346
402328 4464283 Minus 13758-13922,14558-14752
405545 1054740 Plus 118677-118807,119091-119296,121626-12182
402330 4464283 Minus 15325-15380,15484-15588,15842-15915
404440 7528051 Plus 80430-81581
403912 7710730 Minus 72000-72290,72431-72700,72929-73199
404760 7767724 Plus 223266-223352,224472-224585
404883 5101762 Minus 94626-94730,96998-97069
403362 8571772 Plus 64099-64260
405547 1054740 Plus 124361-124520,124914-125050
405546 1054740 Plus 124010-124183
404210 5006246 Plus 169926-170121
Table 18A 194 Up-Regulated Genes in Utenne Cancer Versus Normal Adult Tissues
Table 18A lists about 194 genes up-regulated in utenne cancer compared to normal adult tissues These were selxted from 59680 probesetε on the Affymetrιx/Eos-Hu03 GeneChip array such that the ratio of "average" utenne cancer to "average" normal adult tisεueε was greater than or equal to 30 The "average" utenne cancer level was set to the 2nd highest amongst utenne cancers The "average" normal adult tisεue level was εet to the 90* percenfile value amongεt non-malignant tiεsues In order to remove gene-spxific bxkground levels of non-εpxific hybridization, the 15th percentile value amongst non-malignant tissues was subtrxted from both the numerator and the denominator before the ratio was evaluated.
Pkey: Unique Eos probeset identifier number
ExAccn: Exemplar Accesεion number, Genbank xceεεion number
UnigenelD: Unigene number
Unigene Title:Unigeπe gene title
R1 : Ratio of tumor vs. normal tissue
Pkey ExAccn UnigenelD Unigene Title R1
449034 AI624049 gb:ts41a09.x1 NCI CGAP.Utl Homo sapiens cDNA 55.7
435094 AI560129 Hs.277523 EST 45.2
438817 AI023799 Hs.163242 ESTs 42.6
421478 AI683243 Hs.97258 ESTs 35.2
452838 U65011 Hs.30743 Preferentially expressed antigen in melanoma 27.3
450451 AW591528 Hs.202072 ESTs 26.0
428153 AW513143 Hε.98367 hypothetical protein FU22252 24.8
428187 AI687303 Hε.285529 G protein-coupled rxeptor 49 (GPR49) (HG38) 24.2
438993 AA828995 Hs.52620 integrin; beta 8 16.7
436775 AA731111 Hs.291891 ESTs 14.3
430491 AL109791 Hs.241559 Homo sapiens mRNA full length inεert cDNA clo 13.5
441377 BE218239 Hs.202656 ESTs 13.5
400289 X07820 Hε.2258 Matrix Metalloproteinase 10 (Stromoiysin 2) 12.3
400292 AA250737 Hs.72472 BMPR-lb;bone morphogenetic protein rxeptor lb 10.7
403899 predicted exon 10.1
442438 AA995998 gb:os26b03.s1 NCI CGAP.Kidδ Homo εapienε cDNA 10.0
447350 AI375572 Hs.1939 HER4 (c-erb-B4) 9.8
453964 AI961486 Hs.12744 ESTε 9.7
443830 AI142095 Hs.143273 ESTs 9.1
459325 AW088369 Hε.282184 ESTs 9.0
415245 N59650 Hs.27252 ESTs 8.9
446608 N75217 Hs.257846 ESTs 8.9
426635 BE395109 Hs.129327 ESTs 8.8
433426 H69125 Hs.133525 ESTs 8.7
437960 AI669586 Hs.222194 ESTs 8.5
441081 AI584019 Hs.169006 ESTs, Moderately similar to plakophilin 2b [H 8.3
440048 AA897461 Hs.158469 ESTs, Weakly similar to envelope protein [H.s 7.3
447835 AW591623 Hs.164129 ESTs 7.2
440870 AI687284 Hs.150539 Homo sapiens cDNA FU13793 fis, clone THYRO10 7.1
412925 AI089319 Hs.179243 ESTs 7.0
408562 AI436323 Hs.31141 Roundabout homolog 2 transmembrane rxeptor (robo2) 7.0
429272 W25140 Hs.110667 ESTs 6.9
453197 AI916269 Hs.109057 ESTs, Weakly similar to ALU5.HUMAN ALU SUBFAM 6.3
437938 AI950087 ESTs; Weakly similar to Gag-Pol polypratein 6.2
420610 AI683183 Hs.99348 distal-less homx box 5 6.2
448672 AI955511 Hs.225106 ESTs 6.1
452461 N78223 Hs.108106 transcription fxtor 6.1
413335 AI613318 Hε.48442 ESTs 6.1
449611 AI970394 Hs.197075 ESTs 6.0
449260 AA741180 Hs.29879 ESTs 6.0
412140 AA219691 Hε.73625 RAB6 interacting, kinesin-like (rabkiπeεinθ) 6.0
443715 AI583187 Hε.9700 cyclin El 6.0
432113 AA935065 Hε.152385 ESTs 5.9
424834 AK001432 Hε.153408 Homo εapiens cDNA FU10570 fis, clone NT2RP20 5.7
410658 AW105231 Hε.192035 ESTs 5.7
426465 AI758948 gb:ty16f07j<1 NCI_CGAP_Ut3 Homo sapiens cDNA 5.7
446704 AI337228 Hs.197083 ESTs 5.5
419503 AA243642 Hs.137422 ESTs 5.5
444342 NM.014398 Hε.10887 similar to lysosome-asεxiated membrane glyco 5.4
436076 AI193277 Hs.120954 ESTε 5.4
406687 M31126 Hs.272620 pregnancy εpxific beta-1-glycoprotein 9 5.3
445258 AI635931 Hs.147613 ESTε 5.3
440901 AA909358 Hs.128612 ESTs 5.3
434636 AA083764 Hs.241334 ESTs 5.3
429334 D63078 Hs.186180 Homo sapieπε cDNA: FU23038 fiε, clone LNG020 5.2
418852 BE537037 Hs.273294 hypothetical protein FU20069 5.2
459583 AI907673 gb:IL-BT152-080399-004 BT152 Homo εapienε cDN 5.2
436787 AA908554 Hε.192756 ESTs 5.2
400301 X03635 Hs.1657 Estrogen rxeptor 1 5.1
428771 AB028992 Hs.193143 KIAA1069 protein 5.1
444928 AI685841 Hs.161354 ESTs 5.0
453922 AF053306 Hs.36708 budding uninhibited by benzimidazoles 1 5.0
405609 predicted exon 5.0
410102 AW248508 Hs.279727 ESTε; 5.0
433283 BE041135 Hs.175622 ESTs 4.8
443270 NM.004272 Hs.9192 Homer, neuronal immediate early gene, 1B 4.8
410247 AF181721 Hs.61345 RU2S 4.7
422589 AA312735 Hs.179725 ESTs 4.7
452771 T05477 gb:EST03366 Fetal brain, Stratageπe (cat93620 4.7
407275 AI364186 gb:qw34h07.x1 NCI_CGAP_Ut4 Homo sapiens cDNA 4.7
420440 NM.002407 Hs.97644 mammaglobin 2 4.6
451105 AI761324 gb:wi60b11.x1 NCI_CGAP_Co16 Homo sapiens cDNA 4.6 453616 NM.003462 Hs.33846 dynein, axone al, light intermediate polypept 4.6
424115 AA335497 Hs.293965 ESTs 4.6
414245 BE148072 Hs.75850 WAS protein family, member 1 4.6
423244 AL039379 Hs.209602 ESTs, Weakly similarto ubiquitous TPR motif, 4.5
441031 AH 10684 Hε.7645 fibrinogen, B beta polypeptide 4.5
447048 AW393080 Hε.228320 Homo sapiens cDNA: FLJ23537 fis, clone LNG076 4.4
458861 AI630223 PHD finger DNA binding protein isoform 1 (int 4.4
428758 AA433988 Hε.98502 Homo sapiens cDNA FLJ14303 fis, clone PLACE20 4.3
420149 AA255920 Hs.88095 ESTs 4.3
433479 AW511459 Hs.249972 ESTs 4.3
449416 AI651016 Hs.246311 ESTs 4.3
457551 AW821319 Hs.288928 Homo sapieπε cDNA: FU23296 fis, clone HEP106 4.3
450109 AI539295 Hs.17967 ESTs 4.3
436954 AA740151 Hs.130425 ESTs 4.3
415511 AI732617 Hs.182362 ESTs 4.3
410153 BE311926 Hs.15830 Homo sapienε cDNA FLJ12691 fis, clone NT2RM40 4.3
406411 predicted exon 4.2
416209 AA236776 Hs.79078 MAD2 (mitotic arrest deficient, yeast, homolo 4.2
416456 H57052 Hs.176626 hypothetical protein EDAG-1 4.2
454692 AW813350 gb:MR3-ST0192-100100-024-g07 4.1
452249 BE394412 Hs.61252 ESTs 4.1
436211 AK001581 Hs.80961 polymerase (DNA directed), gamma 4.1
449765 N92293 Hs.206832 EST, Moderately similar to ALU8.HUMAN ALU SUB 4.1
434988 A1418055 Hs.161160 ESTs 4.1
423515 AA327017 Hs.162204 ESTs 4.0
435407 AI149774 Hs.117178 ESTs 4.0
440886 AW511032 Hs.190516 ESTs 4.0
444783 AK001468 Hs.62180 ESTs 4.0
452039 AI922988 Hs.172510 ESTs 4.0
407300 AA102616 Hs.120769 Homo sapiens cDNA FU20463 fis, clone KAT0614 4.0
425176 AW015644 Hs.301430 ESTs, Moderately similar to TEF1 HUMAN TRANSC 4.0
449433 AI672096 Hs.9012 ESTε 3.9
419335 AW960146 Hs.284137 Homo sapiens cDNA FLJ12888 fis, clone NT2RP20 3.9
422711 D60641 Hs.21739 Homo sapiens mRNA; cDNA DKFZp586l1518 3.9
453096 AW294631 Hs.11325 ESTs 3.9
441962 AW972542 Hs.289008 Homo sapiens cDNA: FU21814 fis, clone HEP010 3.9
445034 AW293376 Hs.160323 ESTs 3.8
418677 S83308 Hs.87224 SRY (sex determining region Y)-box 5 3.8
422219 AW978073 gb:EST390182 MAGE resequenceε 3.8
440304 BE159984 Hs.125395 ESTε 3.8
421863 A1952677 Hs.108972 Homo sapiens mRNA; cDNA DKFZp434P228 3.8
431322 AW970622 gb:EST382704 MAGE resequences, MAGK 3.8
400250 predicted exon 3.8
428227 AA321649 Hs.2248 INTERFERON-GAMMA INDUCED PROTEIN 3.8
420092 AA814043 Hs.88045 ESTs 3.8
415138 C18356 Hs.78045 tissue fxtor pathway inhibitor 2 TFPI2 3.8
437212 AI765021 Hs.210775 ESTs 3.8
409867 AW502161 gb:Ul-HF-BR0p-ajr-g-12-O-Ul.r1 NIH_MGC_52 3.7
421477 AI904743 Hε.104650 hypothetical protein FU10292 3.7
427119 AW880562 Hs.114574 ESTs 3.7
458154 AW816379 gb:QV4-ST0234-181199-035-g01 ST0234 3.7
434539 AW748078 Hs.214410 ESTs 3.7
424717 H03754 Hs.152213 winglesε-type MMTV integration site family 3.7
412078 X69699 Hε.73149 paired box gene 8 (PAX-8) 3.7
447342 AI199268 Hs.19322 ESTs; Weakly similar to III! ALU SUBFAMILY J 3.7
413472 BE242870 Hs.75379 solute carrier family 1 (glial high affinity 3.7
446619 AU076643 Hs.313 sxreted phosphoprotein 1 (osteopontin) 3.7
453891 AB037751 Hs.36353 Homo sapiens mRNA full length insert cDNA clo 3.7
443613 AI079356 gb:oz39b09.s1 Soares.NhHMPu.S1 Homo εapieπs c 3.6
441285 NM 002374 Hs.167 micratubule-aεsxiated protein 2 3.6
409731 AA125985 Hs.56145 thymosin, beta, identified in neurablastoma c 3.6
417847 AI521558 Hs.288312 Homo sapiens cDNA: FU22316 fis, clone HRC052 3.6
441484 AA935481 Hε.58972 ESTs 3.6
415802 AA169515 Hs.6006 ESTs 3.6 i
448112 AW245919 Hs.301018 ESTs 3.6
428330 L22524 Hs.2256 matrix metalloproteinase 7 (matrilysin) 3.6
402606 predicted exon 3.6
407905 AW103655 Hs.252905 ESTs 3.6
424917 AI636208 Hs.96901 Homo sapienε cDNA: FU23049 fis, clone LNG025 3.6
436982 AB018305 Hs.5378 εpondin 1 , (f-spondin) extracellular matrix p 3.6
451842 AI820539 Hs.267087 ESTs, Moderately similar to ALU4 HUMAN ALU SU 3.6
455666 BE065813 gb:RC2-BT0318-110 00-012-a08 BT0318 Homo sapi 3.6
431731 BE266322 Hs.211374 ESTs, Weakly similar to SP49.HUMAN SPLICEOSOM 3.6
443695 AW204099 Hs.112759 ESTs, Weakly similarto AF126780 1 retinal sh 3.6
410358 AW975168 Hs.13337 ESTs, Weakly similar to unnamed protein produ 3.6
406030 predicted exon 3.5
409745 AA077391 gb:7B14E12 Chromosome 7 Fetal Brain cDNA Libr 3.5
430481 AA479678 Hs.203269 ESTs, Moderately similar to ALU8.HUMAN ALU SU 3.5
437641 AA811452 Hs.291911 ESTs 3.5
415211 R64730.comp Hs.155986 ESTs; Highly similarto SPERM SURFACE PROTEIN 3.4
443450 N66045 Hs.133529 ESTs 3.4
457438 NM.014053 I Hs.270594 FLVCR protein 3.4
451254 AI571016 Hs.172967 ESTs 3.4 419563 AA526235 Hs 193162 Homo εapienε cDNA FU11983 fis, clone HEMBB10 34
427778 AA412323 Hs 105323 ESTs 33
435031 AI632091 Hs 116877 ESTs 33
407366 AF026942 gb Homo sapienε cιg33 mRNA, partial sequence 33
417411 AW500008 Hs 6966 Human DNA sequence from clone RP1-187J11 on c 33
431548 AI834273 Hs 9711 Homo sapiens cDNA FU 13018 fis, clone NT2RP30 32
432415 T16971 Hε 289014 ESTs 32
423126 AA322245 Hs 290165 ESTs 32
433420 AI674093 Hs 293961 ESTs 32
435174 AA687378 Hs 194624 ESTs 32
444743 AA045648 Hs 11817 nudix (nucleoside diphoεphate linked moiety X 32
452588 AA889120 Hs 110637 Homeo box A10 32
427304 AA761526 Hs 163853 ESTε 32
419917 AA320068 Hs 93701 Homo sapiens mRNA, cDNA DKFZp434E232 (from cl 31
417728 AW138437 Hs 24790 KIAA1573 protein 31
419356 AI656166 Hs 7331 ESTs 31
458627 AW088642 Hs 97984 ESTs, Weakly similarto WASP-family protein [ 31
435185 AA669490 Hs 289109 dimethylarginine dimethylaminohydrolase 1 31
416623 N74925 Hs 38761 Homo εapiens cDNA FU21564 fis, clone COL064 31
405174 predicted exon 31
403776 predicted exon 31
426274 D38122 Hs 2007 tumor necrosis fxtor (ligand) superfamily, m 31
431255 AA497043 Hs 115685 ESTε 31
442353 BE379594 Hs 49136 ESTs 31
456662 NM 002448 Hs 1494 msh (Droεophila) homeo box homolog 1 (formerl 31
416530 U62801 Hs 79361 kallikrein 6 (neurosin, zyme) 31
454392 BE260893 gb 601150677F1 NIH.MGC.19 Homo sapiens cDNA c 31
406400 kallikrein 8 (neuropsin/ovasin) 30
439949 AW979197 Hs 292073 ESTs 30
430704 AW813091 gb RC3-ST0186-240400-111-d07 ST0186 Homo sapi 30
401517 predicted exon 30
417830 AW504786 Hs 132808 epithelial cell transforming sequence 2 oπcog 30
435267 N23797 Hs 110114 ESTs 30
426384 AI472078 ESTs 30
422797 AB033064 Hs 120908 KIAA1238 protein 30
428832 AA578229 gb nl22b12 s1 NCI.CGAP.HSC1 Homo sapiens cDNA 30
449722 BE280074 Hs 23960 cyclin B1 30
418478 U38945 Hs 1174 cyclm-dependent kinase inhibitor 2A 30
422689 AW856665 gb RC3-CT0297-290100-013-d03 CT0297 Homo sapi 30
TABLE 18B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Axesεion Genbank a∞ession numbers
Pkey CAT number Accession
409745 115237.1 AA077391 AI347618 AI361453 AI088754 AW207491 AW960912 AA921874 AA286833 AA150722 BE152353 AW188822 BE152450
409867 1156530 1 AW502161 AW502587 AW502345
422219 213547.1 AW978073 AW978072 AA807550 AA306567
422689 219896 1 AW856665 AA315006 AW954733
426384 266211 1 A1472078 AA377209 AA865807
426465 267664.1 AI758948 AA379527 AA379948 AA379262 AW963933
428832 296144.1 AA578229 AA436432 AA481375 AA481363
430704 322217.1 AW813091 AW206655 AA484440
431322 331543 1 AW970622 AA503009 AA502998 AA502989 AA502805 T92188
437938 44573.2 AI950087 N70208 R97040 N36809 AI308119 AW967677 N35320 AI251473 H59397 AW971573 R97278 W01059 AW967671 AA908598
AA251875 AI820501 AI820532 W87891 T85904 U71456 T82391 BE328571 T75102 R34725 AA884922 BE328517 AI219788 AA884444 N92578 F13493
AA927794 AI560251 AW874068 AL134043 AW235363 AA663345 AW008282 AA488964 AA283144 AI890387 AI950344 AI741346 AI689062 AA282915
AW102898 AI872193 AI763273 AW173586 AW150329 AI653832 AI762688 AA988777 AA488892 AI356394 AW103813 AI539642 AA642789 AA856975
AW505512 AI961530 AW629970 BE612881 AW276997 AW513601 AW512843 AA044209 AW856538 AA180009 AA337499 AW961101 AA251669
AA251874 AI819225 AW205862 AI683338 AI858509 AW276905 AI633006 AA972584 AA908741 AW072629 AW513996 AA293273 AA969759 N75628
N22388 H84729 H60052 T92487 A1022058 AA780419 AA551005 W80701 AW613456 AI373032 AI564269 F00531 H83488 W37181 W78802 R66056
AI002839 R67840 AA300207 AW959581 T63226 F04005
438993 467651 1 AA828995 AA834879 AI926361 442438 542469.1 AA995998 AI916584 R61781 T77332 F07756 F08149 F07647 443613 575391.1 AI079356 W23287 449034 794817.1 AI624049 AW117770 AI858360 451105 859083.1 A1761324 AW880941 AW880937 452771 930983 1 T05477 T07855 AI917711 454392 115882.1 BE260893 AA078319 R85057 AW803024 H85811 AA078293 454692 1229118 1 AW813350 AW816082 AW813476 AW813383 455666 1349545 1 BE065813 BE065788 BE065889 BE065832 458154 491768 1 AW816379 AA888282 AA879046 AA879195 458861 798085.1 AI630223 AI630470
TABLE 18C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22" Dunham I etal , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
401517 7677912 Plus 29278-29770
402606 9909429 Minus 81747-82094
403776 7770611 Minus 1414-1513,1624-1756
403899 7381715 Minus 9144-9350
405174 7108030 Minus 102814-103063
405609 5757553 Minus 42814-43010,43583-43783,4486345033,46429-46554,4781548018,49961-50153,51624-51727,51823-51959,52702- 52918,55469-55601,57111-57307,58169-5829660215-60332,61482 61727
406030 8312328 Minus 96123-96547
406400 9256298 Plus 1553-1712,1878-2140,4252-4385,5922 6077
406411 9256407 Plus 7400-7527
Table 19A 225 Up-Regulated Genes Encoding Extrxellular/Cell Surfxe Proteins, UTERINE Cancer Versus Normal Adult Tissueε
Table 19A lists about 225 genes up-regulated in utenne cancer compared to normal adult tisεueε that are likely to encode extrxellular or cell εurface proteins These were selxted as for Table 18A, except that the ratio was greater than or equal to 20, and the predicted protein contained a structural domain that is indicative of extrxellular Ixalizafion (e g ig ftι3, egf, 7tm domains, signal sequences, transmembrane domains) The predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
PSDomam Protein Structural Domain
R1 Ratio of tumor vs normal tissue
Pkey ExAccn UnigenelD Unigene Title PSDomam R1
452838 U65011 Hs 30743 Preferentially expressed antigen in melanoma TM 273
438993 AA828995 Hs 52620 integπn, beta 8 SS,TM,ιntegnn_B 167
400289 X07820 Hs 2258 Matnx Metalloproteinase 10 (Stromo SS.hemopexin 123
446608 N75217 Hs 257846 ESTs TM 89
433426 H69125 Hs 133525 ESTs TM 87
440870 AI687284 Hs 150539 Homo sapiens cDNA FU13793 fis, clo TM.PAX 71
408562 AI436323 Hs 31141 Roundabout homolog 2 transmembrane SS,TM,ιg,fn3 70
420610 AI683183 Hs 99348 distal less homx box 5 TM.homeobox 62
412140 AA219691 Hs 73625 RAB6 interacting, kmesm like (rab TM.kmesin 60
443715 AI583187 Hs 9700 cyclin E1 TM.cyclin 60
432113 AA935065 Hε 152385 ESTs TM 59
419503 AA243642 Hε 137422 ESTs TM 55
444342 NM.014398 Hε 10887 similarto lysoεome-assxiated memb TM.Lamp 54
436076 AI193277 Hs 120954 ESTs TM 54
406687 M31126 Hs 272620 pregnancy spxific beta-1-glycoprot TM.hemopexm 53
418852 BE537037 Hs 273294 hypothetical protein FU20069 TM 52
459583 AI907673 gb IL-BT152-080399 004 BT152 Homo s TM 52
400301 X03635 Hs 1657 Estrogen receptor 1 TM,hormone_rec,zf-C4 51
405609 predicted exon TM.Myosm tail.myosin head 50
453922 AF053306 Hs 36708 budding uninhibited by benzimidazol TM 50
410102 AW248508 Hs 279727 ESTs, SSJM, 50
433283 BE041135 Hs 175622 ESTs TM 48
443270 NM 004272 Hε9192 Homer, neuronal immediate eariy gen TM 48
410247 AF181721 Hs 61345 RU2S TM 47
422589 AA312735 Hs 179725 ESTs TM 47
407275 AI364186 gb qw34h07 x1 NCI_CGAP_Ut4 Homo sap TM 47
420440 NM 002407 Hs 97644 mammaglobin 2 TM.Uteroglobiπ 46
453616 NM 003462 Hs 33846 dynem, axonemal, light intermediat TM.Riboεomal S27e 46
424115 AA335497 Hs 293965 ESTs TM 46
414245 BE148072 Hs 75850 WAS protein family, member 1 TM.WH2 46
458861 AI630223 PHD finger DNA binding protein isof TM.PHD 44
449416 AI651016 Hs 246311 ESTs SSJM, 43
420149 AA255920 Hs 88095 ESTs TM 43
433479 AW511459 Hs 249972 ESTs TM 43
457551 AW821319 Hs 288928 Homo sapienε cDNA FU23296 fis, cl TM 43
406411 predicted exon TM,vwa,FG-GAP 42
416456 H57052 Hs 176626 hypothetical protein EDAG-1 TM 42
454692 AW813350 gb MR3-ST0192-100100-024-g07 ST0192 TM 41
436211 AK001581 Hs 80961 polymerase (DNA directed), gamma TM 41
434988 AI418055 Hs 161160 ESTs TM ' 41
444783 AK001468 Hs 62180 ESTs TM.PH 40
440886 AW511032 Hs 190516 ESTs TM.FG-GAP 40
425176 AW015644 Hε 301430 ESTs, Moderately similar to TEF1 HU TM,Glyco transf 29JEA 40
445034 AW293376 Hε 160323 ESTs TM 38
418677 S83308 Hs 87224 SRY (εex determining region Y) box TM,HMG_box 38
400250 predicted exon TM.HisLdexetyl 38
428227 AA321649 Hs 2248 interferon gamma induced protein TM.IL8 38
415138 C18356 Hs 78045 tissue fxtor pathway inhibitor 2 T TM.Kumtz BPTI.&gamma 38
458154 AW816379 gb QV4-ST0234-181199 035-g01 ST0234 TM.WW 37
421477 AI904743 Hs 104650 hypothetical protein FU10292 TM 37 413472 BE242870 Hs 75379 solute earner family 1 (glial high TM.SDF 37
447342 AI199268 Hs 19322 ESTs Weakly similar to "» ALU SU TM 37
446619 AU076643 Hs 313 sxreted phosphoprotem 1 (osteopon TM.Osteopontm 37
453891 AB037751 Hs 36353 Homo sapienε mRNA full length inεer TM 37
441285 NM 002374 Hs 167 microtubule assxiated protein 2 TM.tubulin binding 36
409731 AA125985 Hs 56145 thymosin, beta identified in neuro TMJhymos 36
441484 AA935481 Hε 58972 ESTs TM,th3,ιg,Y_phosphatase 36
428330 L22524 Hs 2256 matnx metalloprotemase 7 (matπly SS,Peptιdase_M10 36
407905 AW103655 Hs 252905 ESTs SSJM.Ephπn 36
436982 AB018305 Hs 5378 spondin 1, (f εpondin) extrxellula SSJM 36
402606 predicted exon TM 36
443695 AW204099 Hs 112759 ESTs, Weakly similarto AF126780 1 TM 36
437641 AA811452 Hs 291911 ESTε TM 35
415211 R64730comp Hs 155986 ESTs, Highly similar to SPERM SURFA TM,IQ,Rlla 34
443450 N66045 Hs 133529 ESTs TM 34
457438 NM 014053 Hs 270594 FLVCR protein TM 34
435031 AI632091 Hs 116877 ESTs TM RhoGEF.PH 33
417411 AW500008 Hs 6966 Human DNA sequence from clone RP1-1 TM 33
435174 AA687378 Hs 194624 ESTs TM.SPRY 32
444743 AA045648 Hs 11817 nudix (nucleoside diphosphate liπke TM,mutT 32
433420 A1674093 Hs 293961 ESTε TM 32
419917 AA320068 Hs 93701 Homo sapiens mRNA, cDNA DKFZp434E23 TM 31
417728 AW138437 Hs 24790 KIAA1573 protein TM 31
403776 predicted exon SSJM.IL8 3 1
426274 D38122 Hs 2007 tumor necrosiε fxtor (ligand) supe TMJNF 31
416623 N74925 Hs 38761 Homo sapiens cDNA FU21564fis, cl TM,Ets 3 1
405174 predicted exon TM 31
431255 AA497043 Hs 115685 ESTs TM 31
456662 NM.002448 Hs 1494 msh (Drosophila) homeo box homolog TM.homeobox 31
416530 U62801 Hs 79361 kallikrein 6 (neurosin, zyme) TM.trypεm pro.isomeraεe 31
454392 BE260893 gb 601150677F1 NIH.MGC.19 Homo sapi TM 31
406400 kallikrein 8 (neuropsm/ovasin) TM.trypsin 30
401517 predicted exon TM.HMG14 17 30
417830 AW504786 Hs 132808 epithelial cell transforming sequen TM 30
435267 N23797 Hs 110114 ESTs TM 30
449722 BE280074 Hs 23960 cyclin B1 TM.cyclin 30
418478 U38945 Hs 1174 cyclm-dependent kinase inhibitor 2 TM,ank 30
422689 AW856665 gb RC3-CT0297-290100-013-d03 CT0297 TM.SNF2 N 30
441794 AW197794 Hε 253338 ESTs TM,ank 29
416658 U03272 Hε 79432 fibnllm 2 (congenital contrxtura TM.EGFJB 29
431130 NM.006103 Hε 2719 epididymis-εpxifio, whey-xidic pr SS.wap 29
418113 AI272141 Hε 83484 ESTs TM.HMG box 29
402373 AL135225 Hs 301865 dopxhrome tautomerase (dopxhrome TMJEA 29
431989 AW972870 Hs 291069 ESTs SS 29
400284 Estrogen rxeptor 1 TM,hormone_rec,zf C4 29
438578 AA811244 Hs 164168 ESTs TM formyUraπsf,AIRS,GARS 29
423513 AF035960 Hs 129719 transglutaminase 5 TM ,Tranεglutamιπ_N 28
448966 AW372914 Hs 287462 Homo sapienε cDNA FU11875 fiε, clo TM 28
431870 AW449902 Hs 105500 ESTε TM.MHC l,ιg 28
409457 AW818081 gb CM4-ST0276-101299-059-b09 ST0276 TM 28
438777 AA825487 Hs 142179 ESTε, Weakly similarto ORF2 [M mus TM 28
451807 W52854 Hs 27099 DKFZP564J0863 protein TM 28
433326 AI379486 Hs 159430 ESTs TM 28
448221 BE622615 gb 601440775T1 NIH.MGC.72 Homo sapi TM 28
448141 AI471598 Hε 197531 ESTs TM,bZIP 28
456311 AA225632 Hε 190016 ESTs TM,Sx7 28
405454 predicted exon TM 28
459287 AL079369 gb DKFZp564G2378_r1 564 (synonym h TM 28
438935 H40665 Hε 31564 ESTs TM 27
421312 AA824627 Hs 291670 ESTs TM,G-patch 27
418882 NM 004996 Hs 89433 ATP-binding cassette, sub-family C TM.ABC membrane,ABC fran 27
424345 AK001380 Hs 145479 Homo sapienε cDNA FU10518 fis, clo TM 27
417956 AA210704 Hs 190465 ESTs SS.sushi 27
445537 AJ245671 Hs 12844 EGF-like-domam, multiple 6 SS.EGF 27
448089 AI467945 Hs 173696 ESTs SSJM, 26
446643 AA194417 Hs 282060 ESTε TM.CIaLadaptor.s 26
456671 AB011142 Hs 114293 KIAA0570 gene product TM 26
457256 AA459443 Hs 231816 ESTε SS 26
438986 AF085888 Hs 269307 ESTε TM.Spin Ssty 25
435313 AI769400 Hs 189729 ESTε TM.MBD 25
417351 T90278 Hε 15049 ESTε TM.CH 25
412198 AA937111 Hε 69165 ESTε TM 25
413278 BE563085 Hs 833 interferon stimulated protein, 15 k TM.ubiquit 25
421502 AF111856 Hs 105039 solute earner family 34 (sodium ph TM,Na_Pι_cotranε 25
418092 R45154 Hε 106604 ESTs TM.pkmase 25
410008 AA079552 gb zm20h12 s1 Stratagene pancreas ( TM.FG-GAP 25
420362 U79734 Hε 97206 huntingtjn interacting protein 1 TM.ENTRI LWEQ 25
431974 AW972689 Hs 200934 ESTs TM.bZIP 25
438209 AL120659 Hs 6111 KIAA0307 gene product TM,HLH,PAS 25
447578 AA912347 Hs 136585 ESTs TM 25
414812 X72755 Hs 77367 monokine induced by gamma interfero SS.IL8 25
421515 Y11339 Hs 105352 GalNAc alpha-2, 6-sιalyltransferaεe TM,Glyco_transf_29 24
416402 NM 000715 Hs 1012 ∞mplement component 4-bιπdιπg prot TM.sushi 24 439699 AF086534 Hs 187561 ESTs, Moderately similar to ALU1.HU TM 24
428242 H55709 Hs 2250 leukemia inhibitory fxtor (choline SS.LIF.OSM 24
417693 AW959741 Hs 40368 adaptor-related protein complex 1, TM.CIaLadaptor s 24
428679 AA431765 gb zw80c03 s1 Soareε.testiε.NHT Hom TM.HECT 24
436311 AA708958 Hs 168732 ESTε TM 24
426920 AA393351 Hs 132121 ESTε TM 24
426698 AA394104 Hs 97489 ESTε TM 24
443426 AF098158 Hs 9329 Homo sapiens mRNA for fls353, compl TM 24
406815 AA833930 Hs 288036 tRNA isopentenylpyroptiosphate trans TM.IPPT 24
434808 AF155108 Hs 256150 ESTs, Highly similar to NY-REN-41 a TM 23
432441 AW292425 Hs 163484 EST TM.Fork head 23
435615 Y15065 Hs 4975 potassium voltage-gated channel, KQ TM 23
402298 predicted exon TM zf C2H2,KRAB 23
435542 AA687376 Hs 269533 ESTs TM 23
442952 AI743261 Hs 131860 ESTs TM 23
418203 X54942 Hs 83758 CDC28 protein kinase 2 TM.CKS 23
429228 AI553633 Hs 104985 ESTs TM 23
418969 W33191 Hs 28907 hypothetical protein FU20258 TM.SH3 23
447570 AI868315 Hs 99669 ESTs TM.PHD 23
405032 predicted exon TM.FMO like 23
416566 NM 003914 Hs 79378 cyclin A1 TM.cyclm 23
420900 AL045633 Hs 44269 ESTs TM,FAD_bιndιng_5 23
430563 AA481269 Hs 178381 ESTs TM.ABC membrane,p450 23
417372 T99755 Hs 290814 ESTs TM 23
449083 AI948808 Hs 191144 ESTs TM 23
410361 BE391804 Hs 62661 guanylate binding pratem 1 , interf TM.GBP 23
434131 AI858275 Hs 143659 ESTs TM 23
431846 BE019924 Hs 271580 Uroplakin 1B TM,transmembrane4 23
425638 NM 012337 Hs 158450 nasopharyngeal epithelium spxific TM 23
440006 AK000517 Hs 6844 hypothetical protein FU20510 TM 23
445870 AW410053 Hs 13406 syntaxin 18 TM 23
430639 AW025427 Hs 233552 ESTs TM.pkmase 23
439018 AW300887 Hs 26638 membrane-spanning 4-domaιnε, εubfam SSJM, 23
422095 AI868872 Hs 288966 ceruloplaεmin (ferroxidaεe) SSJM.Cu-oxidase 22
411558 AA102670 Hs 70725 "Human GABA A receptor pi εubunit m TM.neur.chaπ 22
408380 AF123050 Hs 44532 diubiquitin TM ,7tm 3.ANF rxeptor 22
403721 predicted exon TM 22
440711 AA904389 Hε 143511 ESTε TM.rrm 22
457285 AI038858 Hs 228780 ESTε, Highly similar to AF199597 1 TM.efhaπd 22
422956 BE545072 Hs 122579 ESTs TM 22
433482 AI953499 Hs 152617 ESTs TM 22
431980 AA523696 Hs 222695 Homo sapienε cDNA FU20986fiε, cl TM 22
420777 AA280223 Hs 130865 ESTs TM 22
446659 AI335361 Hs 226376 ESTs TM 22
410227 AB009284 Hs 61152 exostoseε (multiple) like 2 TM 22
422282 AF019225 Hs 114309 apolipopratem L TM 22
431701 AW935490 Hs 14658 ESTε TM.Occludin 22
426910 AA470023 Hs 190089 ESTs TM.MMR HSR1 22
405636 Hs 153595 predicted exon SS,TM,EGF,ldl_recepLa 22
401933 predicted exon TM.ion tranε 21
436679 AI127483 Hs 120451 ESTs, Weakly similarto unnamed pro TM 21
451061 AW291487 Hs 213659 ESTs, Weakly similar to KIAA1357 pr TM 21
410664 NM 006033 Hs 65370 lipase, endothelial SSJM.Ribosomal L22,lιpase 21
449378 AW664026 Hs 59892 ESTs TM 21
433345 AI681545 Hs 152982 EST cluster (not in UniGene) TM 21
425851 NM 001490 Hs 159642 glucosaminyl (N-xetyl) transferase SSJM.Braπch 21
431832 AW276866 Hs 192715 ESTs TM,Ets,SAM_PNT 21
448275 BE514434 Hs 20830 synaptio Ras GTPaεe xfivating prot TM.kmesin ,abhydrolaεe_2 21
423049 X59373 Hs 188023 ESTs TM.homeobox 21
427510 Z47542 Hs 179312 small nuclear RNA xtivafing comple TM 21
418076 R61388 Hs 6724 ESTs TM 21
413670 AB000115 Hs 75470 hypothetical protein, expressed in TM 21
429183 AB014604 Hs 197955 KIAA0704 protein TM 21
439031 AF075079 gb Homo sapiens full length insert TM 21
431060 AF039307 Hε 249171 homeo box A11 TM.homeobox 21
451494 AI799444 Hs 247095 ESTs, Moderately similar to ALU7.HU TM 21
419978 NM 001454 Hs 93974 forkhead boxJI TM.Fork head 21
404535 Z25U84 Hs 121483 chloπde channel 1 , skeletal muscl SS 21
445181 AW338972 Hs 147471 ESTs TM 21
452367 U71207 Hs 29279 eyes absent (Drosophila) homolog 2 TM.Hydrolase 21
443591 AI078281 Hs 179240 ESTs TM 21
448105 AW591433 Hs 170675 ESTs, Weakly similar to TMS2.HUMAN TM.trypsm 21
424310 AA338648 Hs 50334 ESTs TM 20
450193 AI916071 Hs 224623 ESTs TM.pkmase 20
436009 H57130 Hs 120925 ESTs SS.TM.Ephπn 20
453313 BE005771 Hs 153746 Homo sapienε cDNA FLJ22490 fis, cl TM 20
419833 AA251131 Hs 220697 ESTs TM.WHEP-TRS 20
437555 AA759263 Hs 14041 ESTs TM.Nramp 20
411828 AW161449 Hs 72290 wingless-type MMTV integration site TM.wnt 20
440052 AI633744 Hs 195648 ESTs T PAC 20
410718 AI920783 Hs 191435 ESTs TM.SQS PSY 20
404767 predicted exon TM 20
447462 AW337214 Hs 158973 ESTs TM 20 442255 AI701857 Hs 202388 ESTs TM 20
410292 AA843087 Hs 124194 ESTε TM 20
442748 AI016713 Hs 135787 ESTs TM 20
458760 AI498631 Hs 111334 ferπtin, light polypeptide TM,HC03_cotransp 20
409799 D11928 Hs 76845 phosphosenne phosphatase-like TM.Hydrolase 20 401324 predicted exon TM myosin.head 20
432140 AK000404 Hs 272688 hypothetical protein FLJ20397 SS 20
447541 AK000288 Hs 18800 hypothetical protein FLJ20281 TM,zf-CCHC 20
421379 Y15221 Hs 103982 small inducible cytokine subfamily SSJM.IL8 20
TABLE 19B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession πumberε
Pkey CAT number Acceεεion
409457 1132521.1 AW818081 AW392887 AW514700 AW392881 410008 116812 1 AA079552 BE142525 BE142527 422689 219896.1 AW856665 AA315006 AW954733 428679 294049.1 AA431765 AA432015 438993 467651 1 AA828995AA834879AI926361 439031 46798.1 AF075079 H48601 H48795 448221 75534 -1 BE622615 454392 115882.1 BE260893 AA078319 R85057 AW803024 H85811 AA078293 454692 1229118.1 AW813350 AW816082 AW813476 AW813383 458154 491768 1 AW816379 AA888282 AA879046 AA879195 458861 798085.1 AI630223 A1630470 459287 977129.1 AL079369 D81804
TABLE 19C
Pkey Unique nun lbercorrespon idmg to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to I human chromosome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exons were predicted
NLpoεition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLpoεition
401324 9863791 Plus 234057-234174
401517 7677912 Plus 29278-29770
401933 3810668 Minus 48725-49057,51864-51955,52424-52589
402298 6598824 Plus 36758-37953
402606 9909429 Minus 81747-82094
403721 7528046 Minus 156647-157366
403776 7770611 Minus 1414-1513,1624-1756
404767 7882827 Minus 23244-23759
405032 7107731 Minus 131945-132224
405174 7108030 Minus 102814-103063
405454 7656675 Plus 133807-134053
405609 5757553 Minus 4281443010,43583-43783,44863-45033,46429-46554,47815-48018,49961-50153,51624-
51727,51823-51959,52702-52918,55469-55601,57111-57307,58169-58296,60215-
60332,61482-61727
405636 5123990 Plus 56384-56587
406400 9256298 Plus 1553-1712,1878-2140,4252-4385,59226077
406411 9256407 Pluε 7400-7527
Table 20A.56 Up-Regulated Genes Encoding Extrxellular/Cell Surfxe Proteins, Utenne Cancer Versus Normal Adult Tissueε
Table 20A lists about 56 genes up-regulated in utenne cancer compared to normal adult tisεueε that are likely to encode either enzymeε or prateinε amenable to modulation by εmall olxuleε Theεe were εelxted aε for Table 18A, except that the ratio was greater than or equal to 20, and the predicted protein contained a structural domain that is indicative of enzymatic function or of being modulated by small molxules (e g pkinase, peptidaεe, lεomerase, tranεporters) The predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
PSDomam Protein Structural Domain
R1 Ratio of tumor vs normal tiεεue
Pkey ExAccn UnigenelD Unigene Title PSDomam R1
428187 AI687303 Hs 285529 G protein-coupled rxeptor 49 (GPR49) 7tm_1 242
400289 X07820 Hs 2258 Matnx Metalloproteinase 10 (Stromoly hemopexm 123
447350 AI375572 Hs 172634 HER4 (c-erb-B4) kinase 98
420610 AI683183 Hs 99348 distal less homx box 5 homeobox 62
405609 predicted exon Myosin tail.myosiπ head 50
458861 NM.007358 Hs 31016 PHD finger DNA binding protein PHD 44
410153 BE311926 Hs 15830 Homo sapienε cDNA FU 12691 fis, clone NA 43 436211 AK001581 Hs 80961 polymerase (DNA dirxted), gamma NA 41
444783 AK001468 Hs 62180 ESTs PH 40
418677 S83308 Hs 87224 SRY (sex determining region Y) box 5 HMG box 38
413472 BE242870 Hs 75379 solute earner family 1 SDF 37
443613 AI079356 Hs 21807 gb oz39b09 s1 Soares.NhHMPu.S1 Homo s zf C2H2 36
428330 L22524 Hs 2256 matnx metalloproteinase 7 (malrilysin) Peptidase M10 36
443695 AW204099 Hs 112759 ESTs Weakly similar to AF126780 1 re NA 36
435031 AI632091 Hs 116877 ESTs RhoGEF.PH 33
417411 AW500008 Hs 6966 Human DNA sequence from clone RP1-187 NA 33
435185 AA669490 Hs 289109 dimethylargmine dimethylamtnohydrola NA 31
416530 U62801 Hs 79361 kallikrein 6 (neurosin, zyme) trypsin.projsomerase 31
406400 AA343629 Hs 104570 kallikrein 8 (neuropsm/ovasin) trypsin 30
418478 U38945 Hs 1174 cyclm-dependent kinase inhibitor 2A ank 30
441794 AW197794 Hε 253338 ESTs ank 29
402373 AL135225 Hs 301865 dopxhrome tautomerase (dopxhrome de TEA 29
423513 AF035960 Hs 129719 transglutaminase 5 Transglutamin N 28
448141 AI471598 Hs 197531 ESTε bZIP 28
415076 NM 000857 Hs 77890 guanylate cyclase 1, soluble, beta 3 guanylate.cyc 27
418882 NM 004996 Hs 89433 ATP-binding cassette, sub-family C ABC membrane.ABC tran 27
448435 BE293439 Hs 182278 calmoduliπ 2 NA 26
417351 T90278 Hs 15049 ESTs CH 25
430372 AI206173 Hs 211375 ESTs SH3,efhand,C2,PH 25
431974 AW972689 Hs 200934 ESTs bZIP 25
428046 AW812795 Hs 155381 ESTε Moderately similar to I38022 hy ank 24
421515 Y11339 Hs 105352 GalNAc alpha-2, 6-sιalyltraπsferase I Glyco_tranεf_29 24
403095 predicted exon homxbox.PAX 24
406815 AA833930 Hs 288036 tRNA isopentenylpyrophoεphate tranεfe IPPT 24
435615 Y15065 Hs 4975 potassium voltage-gated channel ιon_channel 23
402298 predicted exon zf-C2H2,KRAB 23
418203 X54942 Hs 83758 CDC28 protein kinase 2 CKS 23
430563 AA481269 Hε 178381 ESTs ABC membrane p450 23
447570 AI868315 Hε 99669 ESTs PHD 23
439018 AW300887 Hs 26638 membrane-spanning 4-domaιns, εubfamil NA 23
415539 AI733881 Hs 72472 BMPR-lb, bone morphogenetio protein NA 22
422095 AI868872 Hs 288966 ceruloplasmm (ferraxidase) Cu-oxidase 22
408380 AF123050 Hs 44532 diubiquitm ANF_rxeptor,sushι,7tm_1 22
440711 AA904389 Hs 143511 ESTs rrm 22
457285 AI038858 Hs 228780 ESTs, Highly similar to AF199597 1 A- efhand 22
418506 AA084248 Hs 85339 G protein-coupled rxeptor 39 NA 22
410664 NM 006033 Hs 65370 lipase, endothelial Rιbosomal_L22,lιpase,PLAT 21
425851 NM 001490 Hs 159642 glucosaminyl (N xetyl) traπsferase 1 Branch 21
448275 BE514434 Hs 20830 εynaptic Ras GTPase xtivating protein kmesin.PHD.abhydrolase 2 21
429782 NM.005754 Hs 220689 Ras-GTPase-xtJvating protein SH3-dom rrm,NTF2 21
404535 Z25884 Hs 121483 chloπde channel 1 , skeletal muscle NA 21
448105 AW591433 Hs 170675 ESTs, Weakly similar to TMS2 trypsin 21
446342 BE298665 Hs 14846 Cationic am o xid transporter (xto NA 20
458760 AI498631 Hs 111334 ferπtin, light polypeptide HC03_cotransp zf-C3HC4 20
409799 D11928 Hs 6845 phosphoseπne phoεphatase-like Hydrolase 20
401324 predicted exon myosm.head 20
TABLE 20B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank a∞esεion numberε
Pkey CAT number Accession
443613 5753911 AI079356W23287 458861 798085.1 AI630223 AI630470
TABLE 20C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positionε of predicted exonε Pkey Ref Strand NLposition
401324 9863791 Plus 234057-234174 402298 6598824 Plus 36758-37953 403095 8954339 Plus 150025-150240,151564-151690 405609 5757553 Minus 42814-43010,43583-43783,44863-45033,46429-46554,47815-4801849961 -50153,51624-
51727,51823-51959,52702-52918,55469-55601 ,57111-57307,58169-58296,60215-
60332,6148261727
406400 9256298 Plus 1553-1712 1878-2140,42524385,5922-6077 Table 21 A: 270 Up-Regulated Genes, Uterine Cancer Versuε Normal Uteruε
Table 21 A lists about 270 genes up-regulated in uterine cancer compared to normal uterus. These were selxted as for Tabte 18A, except that the ratio was greater than or equal to
5.0, and the denominator was the median value for six non-malignant uterine spximens.
Pkey: Unique Eos probeset identifier number
ExAccn: Exemplar Accession number, Genbank xceεεion number
UnigenelD: Unigene number
Unigene Title: Unigene gene title
R1 : Ratio of tumor vs. normal tissue
Pkey ExAccn UnigenelD Unigene Title R1
449034 AI624049 gb:tε41a09.x1 NCI CGAP Ut1 Homo sapiens 55.7
435094 AI560129 Hs.277523 EST 45.2
438461 AW075485 Hs.286049 phosphoserine aminotransferase 19.5
434779 AF153815 Hs.50151 potassium inwardly-rectifying channel 15.6
441633 AW958544 Hs.112242 ESTs 15.2
429183 AB014604 Hs.197955 KIAA0704 protein 14.6
436775 AA731111 Hε.291891 ESTs 14.3
441031 AI110684 Hε.7645 fibrinogen, B beta polypeptide 14.0
446921 AB012113 Hs.16530 CC chemokine SCYA18 (MIP4) (PARC) 13.0
413753 U17760 Hs.301103 Laminin, beta 3 (nicein (125kD), kalinin 12.9
421515 Y11339 Hs.105352 GalNAc alpha-2, 6-sialyltranεferase I, I 12.2
414646 AA353776 Hs.901 CD48 antigen (B-cell membrane protein) 12.0
453891 AB037751 Hε.36353 Homo sapiens mRNA full length insert cDN 11.7
425196 AL037915 Hs.155097 carbonic anhydrase II 11.4
444863 AW384082 Hs.301323 ESTs 11.3
449785 AI225235 Hε.288300 Homo sapiens cDNA: FLJ23231 fis, clone C 11.1
446839 BE091926 Hs.16244 mitotic spindle coiled-coil related prot 10.9
449801 AA477355 Hs.288300 Homo sapiens cDNA: FU23231 fis, clone C 10.3
411773 NM.006799 Hs.72026 .protease, serine, 21 (teεfiεin) 10.3
414812 X72755 Hs.77367 monokine induced by gamma interferon 10.2
410361 BE391804 Hs.62661 guanylate binding protein 1, iπterferon- 10.1
423645 AI215632 Hs.147487 ESTs 10.1
442438 AA995998 gb:os26b03.s1 NCI CGAP Kid5 Homo sapiens 10.0
415786 AW419196 Hε.257924 ESTs 10.0
458017 AA813426 Hs.192034 ESTs, Weakly similar to KIAA0705 protein 10.0
435525 AI831297 Hs.123310 ESTs 9.9
413335 AI613318 Hs.48442 ESTs 9.7
420297 AI628272 Hs.88323 ESTs 9.6
452799 AI948829 Hs.213786 ESTs 9.6
434311 BE543469 Hs.266263 Homo sapienε cDNA FU 14115 fiε, clone MA 9.4
408243 Y00787 Hs.624 interleukin 8 9.3
430713 AA351647 Hs.2642 eukaryotic translation elongation fxtor 9.3
452092 BE245374 Hs.27842 hypothetical protein FU11210 9.2
444342 NM.014398 Hs.10887 similarto lysosome-associated membrane 9.2
443830 AI142095 Hs.143273 ESTs 9.1
442547 AA306997 Hs.268362 ESTs, Weakly similar to hypothetical pro 9.0
421633 AF121860 Hs.106260 sorting nexin 10 9.0
403381 0 8.9
426635 BE395109 Hs.129327 ESTs 8.8
440500 AA972165 Hs.150308 ESTε 8.7
436291 BE568452 Hs.5101 ESTε; Highly εimilar to protein regulati 8.7
431668 AW969610 Hs.151179 ESTs 8.7
439018 AW300887 Hs.26638 membrane-spanning 4-domains, subfamily A 8.7
424966 AU077312 Hs.153985 solute camerfamily 7 (cationic amino 8.6
425495 AA358454 Hs.78026 ESTs, Weakly similar to similar to ankyr 8.6
428862 NM.000346 Hε.2316 SRY (sex-determining region Y)-box 9 8.5
438986 AF085888 Hs.269307 ESTs 8.4
422731 AL138411 gb:DKFZp434A1229_r1 434 (synonym: htes3) 8.4
441081 AI584019 Hs.169006 ESTs, Moderately similarto plakophilin 8.3
415992 C05837 Hs.145807 Homo εapieπs cDNA FU13593 fiε, clone PL 8.2
431211 M86849 Hs.5566 Homo sapiens connexin 26 (GJB2) mRNA, co 8.2
409865 AW502208 gb:UI-HF-BROp-aju-e-09-0-UI. NIH.MGC 5 8.0
448158 AI627292 Hs.190877 ESTs 8.0
401519 0 7.9
441730 AI243276 Hs.149017 ESTs 7.9
432441 AW292425 Hε.163484 EST 7.8
448275 BE514434 Hε.20830 syπaptio Ras GTPase xtivating protein 1 7.8
438424 AI912498 Hε.25895 ESTs, Weakly similarto PI-3 kinase [H.s 7.8
447342 AI199268 Hε.19322 ESTs; Weakly similar to III! ALU SUBFAMI 7.7
408369 R38438 Hε.182575 solute earner family 15 (H+/peptide tra 7.7
423081 AF262992 Hs.123159 sperm asεxiated antigen 4 7.6
414484 BE314385 gb:601154649F1 NIH.MGC.19 Homo εapienε o 7.6
420931 AF044197 Hs.100431 small inducible cytokine B subfamily (Cy 7.6
459142 AI903396 gb:RC-BT029-120199-219 1 BT029 Homo sapi 7.5
411094 BE066142 gb:CM4-BT0320-221199-047-g10 BT0320 Homo 7.5
436679 AI127483 Hs.120451 ESTs, Weakly similarto unnamed protein 7.5
452607 AI160029 Hs.61438 ESTs 7.5
443171 BE281128 Hε.9030 TONDU 7.4
459081 W07808 gb:zb03a12.r1 Soares.fetal.lung NbHL19W 7.4
431195 AA503083 Hs.79742 ESTs 7.4
444459 AI680624 Hs.148676 ESTs 7.4 422765 AW409701 Hs 1578 bxuloviral IAP repeat-containing 5 (sur 73
414918 AI219207 Hs 72222 Hypothetical protein FU 13459 73
429334 D63078 Hs 186180 Homo sapiens cDNA FU23038 fis, clone L 73
448865 R35027 gb yg60g02 r1 Soares infant brain 1NIB H 73
409219 AA393383 Hs 133331 ESTs 73
400491 H25530 Hs 50868 solute camerfamily 22 (organic cation 72
403485 0 72
408350 AW183350 Hs 250127 ESTs 72
445873 AA250970 Hs 251946 Homo sapiens cDNA FU23107 fiε, clone L 71
400995 0 71
406086 0 71
403378 0 70
426227 U67058 Hε 168102 Human proteinase xtivated rxeptor-2 mR 70
422038 R39098 Hs 192028 ESTs 70
431842 NM 005764 Hs 271473 epithelial protein up-regulated in carci 69
429732 U20158 Hs 2488 lymphxyte cytosolic protein 2 (SH2 doma 69
427494 AI628365 Hs 130412 ESTs Weakly similar to εre-2 [Celeganε 69
429272 W25140 Hs 110667 ESTs 69
427258 AA400081 Hs 39421 ESTs 69
449309 AW58S823 Hs 224189 ESTs 69
400104 0 69
416402 NM.000715 Hs 1012 complement component 4-bιndmg protein 68
404767 0 68
406690 M29540 Hs 220529 CEA (carcinoembryonic antigen related ce 68
439750 AL359053 Hs 57664 ESTs 68
403127 AI904493 Hs 99890 polymerase (DNA dirxted), delta 1, cata 68
418203 X54942 Hs 83758 CDC28 protein kinase 2 68
425858 AA364923 gb EST75602 Pineal gland II Homo sapiens 68
421712 AK000140 Hs 107139 hypothetical protein 67
456903 D49441 Hs 155981 mesothelin 67
414564 AA164803 Hs 71994 ESTs 67
457942 AW665665 Hs 153034 ESTs 67
410442 X73424 Hs 63788 prapioπyl Coenzyme A carboxylase, beta p 67
424596 AB020639 Hs 151017 estrogen related rxeptor gamma 67
445537 AJ245671 Hs 12844 EGF like-domain, multiple 6 67
429597 NM 003816 Hs 2442 a disintegnn and metalloprotemase doma 66
413472 BE242870 Hs 75379 solute earner family 1 (glial high affi 66
410664 NM 006033 Hs 65370 lipase, endothelial 66
428575 M19684 Hs 184929 seπne (or cysteine) proteinase inhibito 66
406400 kallikrein 8 (neuropsin/ovasin) 66
426317 AA312350 Hs 169294 transcnption fxtor 7 (T-cell spxific, 65
441460 AI962478 Hs 226804 ESTs, Moderately similar to ALUC.HUMAN ι 65
412570 AA033517 Hs 74047 elxtron transfer-flavoprotein, beta pol 65
424349 AF141289 Hs 145550 solute camerfamily 7 (cationic am o 65
448681 AL109781 Hs 21754 Homo sapiens mRNA full length insert cDN 64
445258 AI635931 Hs 147613 ESTs 64
456032 AW957446 Hs 301711 ESTs 64
404727 0 64
422810 AA317400 gb EST19374 Retina II Homo εapienε cDNA 64
440044 AW665167 Hs 259563 EST 64
416498 U33632 Hs 79351 potassium channel, subfamily K, member 1 64
426600 NM.003378 Hs 171014 VGF nerve growth fxtor inducible 64
422170 AI791949 Hs 112432 anti Mulleπan hormone 64
449611 AI970394 Hs 197075 ESTs 64
402539 AW502761 Hs 30909 KIAA0430 gene product 63
456983 AI081687 Hε 170225 thymopoietin 63
407910 AA650274 Hε 41296 fibronectin leucine nch transmembrane p 63
457887 AI240007 Hε 148812 ESTs 63
431765 AF124249 Hε 268541 novel SH2-contaιnιng protein 1 63
420344 BE463721 Hs 97101 Putative G protein-coupled rxeptor GPCR 62
443494 T99719 Hs 270404 Homo sapienε cDNA FU22389 fis, clone H 62
456844 AI264155 Hs 152981 CDP-dixylglyceral synthase (phosphatida 62
416623 N74925 Hs 38761 Homo sapiens cDNA. FU21564 fis, clone C 62
413982 BE503035 Hs 279193 ESTs 62
458091 AF150286 gb AF150286 Human mRNAfram cd34+ stem c 62
402104 0 62
428771 AB028992 Hs 193143 KIAA1069 protein 61
435313 AI769400 Hs 189729 ESTs 61
441666 AI188346 Hs 301776 ESTs 61
416111 AA033813 Hs 79018 chromatin assembly fxtor 1, subunit A ( 61
427308 D26067 Hs 174905 KIAA0033 protein 61
423069 W15613 Hs 1613 adenosιneA2a rxeptor 61
416655 AW968613 Hs 79428 BCL2/adenovιrus E1B 19kD-ιnteractιng pro 61
417079 U65590 Hs 81134 interleukin 1 rxeptor antagonist 61
449409 AI650935 Hs 301694 ESTs 61
400855 0 61
454692 AW813350 gb MR3-ST0192-100100-024-g07 ST0192 Homo 60
414869 AA157291 Hs 72163 ESTs 60
439662 H97552 Hs 269060 ESTε 60
445181 AW338972 Hs 147471 ESTε 60
437129 AL049327 gb Homo εapienε mRNA, cDNA DKFZp564E016 60
440128 AA962623 Hs 189144 ESTs, Weakly similar to NPT2.HUMAN RENAL 60
443715 AI583187 Hs9700 cyclin E1 60 422355 AW403724 Hs 140 immunoglobulin heavy constant gamma 3 59
405291 0 59
432113 AA935065 Hs 152385 ESTε 59
441236 AA923489 Hs 130432 ESTs 59
424418 BE503432 Hs 66170 HSKM B protein 59
453028 AB006532 Hs 31442 RxQ protein like 4 58
407137 T97307 Hs 199067 EST 58
443462 AI064690 Hε 171176 ESTs 58
454392 BE260893 gb 601150677F1 NIH MGC 19 Homo sapiens c 58
456311 AA225632 Hε 190016 ESTs 58
446501 AI302616 Hs 150819 ESTs 58
433921 AA618174 gb πq14f01 s1 NCI CGAP Thy1 Homo sapiens 58
409615 AW444861 gb UI H BI3-ajz a-04-O-UI s1 NCI CGAP Su 58
459360 BE384526 gb 601277913F1 NIH MGC 20 Homo sapiens c 58
403824 0 58
428187 AI687303 Hs 285529 G protein-coupled receptor 49 (GPR49) 58
412140 AA219691 Hs 73625 RAB6 interacting, kinesm like (rabkmes 57
410658 AW105231 Hs 192035 ESTs 57
426465 A1758948 gb ty16f07 x1 NCI.CGAP.Ut3 Homo sapiens 57
443695 AW204099 Hs 112759 ESTs, Weakly similar to AF126780 1 retin 57
437372 AA323968 Hs 283631 hypothetical protein DKFZp547G183 57
405392 0 57
437100 AI761073 Hs 14535 Homo sapiens cDNA FLJ22314 fis, clone H 57
449796 AA004321 Hs 194397 ESTs 57
409361 NM.005982 Hs 54416 sine ∞ulis homeobox (Drosophila) homolo 57
428987 NM.004751 Hs 194710 glucosammyl (N xetyl) transferase 3 57
404220 0 56
420973 AA743415 Hs 291368 ESTε 56
430491 AL109791 Hs 241559 Homo εapienε mRNA full length insert cDN 56
442549 AI751601 Hs 8375 TNF rxeptor assxiated fxtor 4 56
409867 AW502161 gb UI-HF-BROp-ajr-g 12 0-UI r1 NIH.MGC.5 56
451110 AI955040 Hs 301584 ESTs 56
418216 AA662240 Hs 283099 AF15q14 protein 56
411897 AW875066 gb RC6-PT0001-180100-021 F04 PT0001 Homo 56
456161 BE264645 Hs 282093 Homo sapiens cDNA FU21918 fis, clone H 56
406536 0 56
432540 AI821517 Hs 105866 ESTs 56
446315 NM.016293 Hs 14770 bπdgmg integrator 2 56
443270 NM.004272 Hs 9192 Homer, neuronal immediate early gene, 1 B 56
451035 AU076785 Hs 430 plastiπ 1 (I isoform) 56
406685 M18728 gb Human nonspxificcrossrexting antig 55
454590 AW809762 Hs 222056 Homo sapiens cDNA FU11572 fis, clone HE 55
402430 0 55
446704 AI337228 Hs 197083 ESTs 55
435282 AA677428 Hs 189731 ESTs 55
426062 N57014 Hs 44013 ESTs 55
415451 H19415 Hs 268720 ESTs, Moderately similar to ALU1.HUMAN A 55
456002 AI628729 Hs 191450 ESTs, Weakly similarto type II membrane 55
409613 AW444816 Hs 171537 Homo sapiens cDN A FU21596 fis, clone C 55
430259 BE550182 Hs 127826 RalGEF-like protein 3, mouse homolog 55
434609 R76593 gb yι60o11 r1 Soares plxenta Nb2HP Homo 55
430250 NM.016929 Hs 283021 chloπde intracellular channel 5 55
418327 U70370 Hs 84136 paired like homeodomain transcnption fa 54
400379 NM 018432 Hs 283076 Homo εapiens ovanan cancer related prot 54
436076 AI193277 Hs 120954 ESTs 54
432119 T80289 gb yd03h04 r1 Soares infant brain 1 NIB H 54
417175 R44558 Hs 94002 ESTε 54
445774 AI254165 Hs 145504 ESTs 54
455604 BE011183 gb PM3-BN0218-100500-003-d09 BN0218 Homo 54
411426 BE141714 gb QVO-HT0101 061099 032-c04 HT0101 Homo 54
445262 AW205650 Hε 253503 ESTs 54
412517 BE271584 gb 601141065F1 NIH MGC 9 Homo sapiens cD 54
434756 AA827650 Hs 259307 ESTs 53
454417 AI244459 Hs 110826 tπnucleotide repeat containing 9 53
439949 AW979197 Hs 292073 ESTs 53
414995 C18200 gb C18200 Human plxenta cDNA (TFujiwara 53
428071 AF212848 Hs 182339 transcnption fxtor ESE-3B 53
412323 AW937143 gb PM1 DT0041-281299-001-f01 DT0041 Homo 53
434283 AW235341 Hs 58715 mouse thiamin pyrophosphokinase homolog 53
447798 AI425049 Hs 119629 ESTs, Moderately similar to ALU1 HUMAN A 53
401723 0 53
406270 0 53
452194 AI694413 Hs 298262 ESTε, Weakly similar to dJ88J81 [H sapi 53
415757 AA830854 Hs 187810 ESTs 53
430051 AA464611 Hs 52515 transducm (beta) like 2 52
435615 Y15065 Hs 4975 potassium voltage-gated channel KQT-lik 52
459583 AI907673 gb IL BT152-080399-004 BT152 Homo sapien 52
449009 BE044755 Hs 224812 ESTs 52
424001 W67883 Hs 137476 KIAA1051 protein 52
409479 BE163800 Hs 136912 ESTs 52
437852 BE001836 Hs 256897 ESTs Weakly similarto dJ365012 1 [H sa 52
435928 H64345 Hs 183961 ESTs 52
447397 BE247676 Hs 18442 E-1 enzyme 52 449183 AW445022 Hs.196985 Homo sapiens cDNA: FLJ21135 fis, clone C 5.2
410146 AW592655 gb:hf45f12.x1 Soares NFL.T GBC S1 Homo s 5.2
458164 AI208666 Hs.192081 ESTs 5.2
410153 BE311926 Hs.15830 Homo εapiens cDNA FU12691 fis, clone NT 5.1
439509 AF086332 Hs.58314 ESTs 5.1
422569 BE552132 Hs.118442 cyclin C 5.1
430664 AW969834 gb:EST381912 MAGE resequenceε, MAGK Homo 5.1
411231 AW833501 gb:QV4-TT0008-091199-025-e09 TT0008 Homo 5.1
412194 AW900282 Hε.115412 Homo εapiens cDNA FU13881 fis, clone TH 5.1
425188 AK002052 Hs.155071 hypothetical protein FU11190 5.1
417173 U61397 Hs.81424 ubiquitin-like 1 (sentrin) 5.1
433279 AW971745 gb:EST383834 MAGE reεequences, MAGL Homo 5.1
454112 NM.000885 Hs.301806 ESTε 5.1
423261 Z43509 gb:HSC1 EA031 normalized infant brain cDN 5.1
434084 AI061640 Hs.192788 hypothetical protein PRO1905 5.1
446115 AI733075 Hs.292682 ESTs, Weakly similar to S69913 hypertens 5.1
416719 H79731 gb:yu81f12.r1 Soares fetal liver spleen 5.1
421462 AF016495 Hs.104624 aquaporin 9 5.1
424517 AI539443 Hs.137447 Homo sapienε cDNA FU12169 fis, clone MA 5.1
403383 0 5.1
430832 AI073913 Hs.100686 ESTs, Weakly similar to sxreted cement 5.1
436070 AK000073 gb:Homo sapienε cDNA FLJ20066 fiε, clone 5.0
416969 AI815443 Hs.283404 organic cation tranεporter 5.0
444929 AI685841 Hs.161354 ESTε 5.0
453922 AF053306 Hε.36708 budding uninhibited by benzimidazoleε 1 5.0
439031 AF075079 gb:Homo εapienε full length insert cDNA 5.0
414539 BE379046 gb:601236646F1 NIH.MGC.44 Homo sapiens c 5.0
425349 AA425234 Hε.79886 ribose 5-phosphate isomerase A (ribose 5 5.0
449986 AW864502 gb:PM4-SN0016-120400-004-b12 SN0016 Homo 5.0
418717 AI334430 Hs.86984 ESTε 5.0
438769 AA830684 Hs.163426 ESTε 5.0
441859 AW194364 Hs.128022 ESTs, Weakly similar to FIG1 MOUSE FIG-1 5.0
446469 BE094848 Hs.15113 homogentisate 1,2-dioxygenase 5.0
TABLE 21 B
Pkey: Unique Eos probeset identifier number
CAT number Gene cluster number Accession: Genbank xcession numbers
Pkey CAT number Acceεεion
409615 1143425 1 AW444861 BE074994 BE074966 BE074992
409865 1156518 1 AW502208 AW502366 AW502148
409867 1156530 1 AW502161 AW502587 AW502345
410146 1178974 1 AW592655 R05927 R06916
411094 1231982 1 BE066142AW817074
411231 1236356 1 AW833501 AW833506 AW833722 AW833332 AW833509 AW833511 AW833767 AW833339
411426 1245515 1 BE141714 AW845993 AW845989
411897 1264907 1 AW875066 AW875079 AW875075 AW875062 AW875061 AW875074
412323 1288770.1 AW937143AW937150AW937141 AW937151 AW937132AW937160AW937191 AW937174AW937195 AW937173
AW937159 AW937139 AW937171 AW937142 AW937145 AW937165 AW937163 AW937164 AW937137 AW937179
AW937156 AW937140 AW937135 AW937170
412517 130281 1 BE271584 AA112511
414484 1452830.-1 BE314385
414539 1460320 1 BE379046 BE395459
414995 1511736.1 C18200 D78681 T82025
416719 1611345 1 H79731 H79732
422731 220507 1 AL138411 AL138412AA315860
422810 221630 1 AA317400AA434584
423261 226553.1 Z43509 H09001 AA375202 AW954383
425858 257265 1 AA364923 AW963483 BE182774 C21461
426465 267664.1 AI758948 AA379527 AA379948 AA379262 AW963933
430664 321423 1 AW969834AA528493 AA483165AW969842
432119 34170 1 T80289 AF052168
433279 361800 1 AW971745 AA581359 AA581358
433921 377350 1 AA618174 AI114549 R36464 R36465
434609 38950 1 R76593AF147390 R76594
436070 41426 1 AK000073 AA380183AA380181 AW963533
437129 43343 1 AL049327AA847105
439031 46798.1 AF075079 H48601 H48795
442438 542469 1 AA995998 AI916584 R61781 T77332 F07756 F08149 F07647
448865 78535 1 R35027 R12034 BE407120
449034 794817 1 A1624049 AW117770 AI858360
449986 821463 1 AW864502 AW864369 AI678780
454392 115882.1 BE260893 AA078319 R85057 AW803024 H85811 AA078293
454692 1229118 1 AW813350AW816082AW813476 AW813383
455604 1337197 1 BE011183 BE011170 BE011333 BE011188 BE011181 BE011324 BE011161 BE011169
458091 472385 1 AF150286AA835857
459081 889426 1 W07808AI822066
459142 918906 1 AI903396A1903361 AI903360
TABLE 21 C Pkey: Unique number correεponding to an Eos probeεet
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489495. Strand: Indicates DNA strand from which exons were predicted.
NLposition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLposition
400855 1931571 Minus 17801-18228
400995 8099084 Plus 141186-141601
401519 6649315 Plus 157315-157950
401723 7656694 Plus 147273-147503
402104 8119072 Plus 122409-122600
402430 9796372 Minus 62382-62552
403378 9438244 Minus Φ1264-44443
403381 9438267 Minus 26009-26178
403383 9438267 Minus 119837-121197
403485 9966528 Plus 2888-3001 ,3198-3532,3655-4117
403824 9798468 Plus 473-887
404220 6706820 Plus 4610746439
404727 8081050 Plus 115534-115747
404767 7882827 Minus 23244-23759
405291 3845420 Plus 19999-20473,20672-21036,21147-21285,21378-21667
405392 6624069 Minus 116167-116289,118879-119030
406086 7107817 Pluε 9418-9573
406270 7534217 Pluε 13136-13591
406400 9256298 Plus 1553-1712,1878-2140,42524385,5922-6077
406536 7711478 Plus 25655-25782
TABLE 22A: 430 SIGNIFICANTLY DOWN-REGULATED GENES, UTERINE CANCER VERSUS NORMAL UTERUS Table 22A lists about 430 genes significantly down-regulated in uterine cancer compared to normal uterus. These were selxted as for Table 21 A, except that the numerator and denominator were switched, and the ratio was greater than or equal to 14 (i.e. 14-fold down-regulated in tumor vs. normal uterus).
Pkey: Unique Eos probeset identifier number
ExAccn: Exemplar A∞esεion number, Genbank xcession number UnigenelD: Unigene number Unigene Title: Unigene gene title R1: Ratio of tumor vs. normal tissue
Pkey ExAccn UnigenelD Unigene Title R1
414063 H26904 Hs.75736 apolipopratem D 93.0
447990 BE048821 Hs.20144 small inducible cytokine subfamily A, member 14 75.7
407815 AW373860 Hs.301716 ESTs 68.7
452547 AA335295 Hs.74120 adipose spxific 2 61.1
415165 AW887604 Hs.78065 complement component 7 55.1
453655 AW960427 Hs.300878 ESTs, Moderately similar to TGR3 HUMAN TGF-BE 54.0
429350 AI754634 Hs.131987 ESTs 52.6
407228 M25079 Hs.155376 hemoglobin, beta 52.0
425869 AA524547 Hs.160318 FXYD domain-containing ion transport regulato 51.6
416585 X54162 Hε.79386 leiomodin 1 (smooth muscle) 51.4
408614 AL137698 Hε.46531 Homo sapienε mRNA; cDNA DKFZp434C1915 (from c 49.7
417542 J04129 Hs.82269 progestagen-asε∞iatedendometrial protein (p 49.3
412295 AW088826 Hs.22971 ESTs 48.0
421998 R74441 Hs.117176 poly(A)-binding protein, nuclear 1 47.0
452093 AA447453 Hs.27860 Homo sapiens mRNA; cDNA DKFZp586M0723 (from c 46.7
429707 W76631 Hs.211819 matrix metalloproteinase 23B 45.7
416950 AL049798 Hs.80552 dermatopontin 45.6
408221 AA912183 Hε.47447 ESTs 44.6
406791 AI220684 Hs.272572 hemoglobin, alpha 2 43.0
446500 U78093 Hs.15154 suεhi-repeat-contaiπing protein, X chromosome 42.6
407938 AA905097 Hs.85050 phospholamban 41.1
410677 NM 003278 Hs.65424 tetranxtin (plaεminogen-binding protein) 41.0
412524 AA417813 Hs.11177 ESTs 39.4
452426 AI904823 Hs.31297 Homo sapiens cDNA: FU23001 fis, clone LNG002 38.6
414290 AI568801 Hs.71721 ESTs 38.2
439627 BE621702 Hs.29076 Homo εapieπs cDNA: FU21841 fis, clone HEP018 38.0
400258 Hs.79064 deoxyhypusine synthase 37.0
414807 AI738616 Hs.77348 hydroxyprostaglandin dehydrogenase 15-(NAD) 36.1
410023 AB017169 Hs.57929 slit (Drosophila) homolog 3 35.4
407663 NM 016429 Hs.37482 COPZ2 for πondathrin coat protein zeta-COP 34.3
410286 AI739159 Hs.61898 DKFZP586N2124 protein 33.8
418986 AI123555 Hs.81796 ESTs 33.1
409060 AI815867 Hs.50130 nxdin (mouse) homolog 33.1
436569 BE439539 Hs.279837 glutathione S-transferase M2 (muscle) 32.8
420674 NM 000055 Hs.1327 butyrylcholiπesterase 32.6
417967 BE244373 Hs.1119 nuclear rxeptor subfamily 4, group A, member 32.4
450810 BE207588 Hs.25511 transforming growth fxtor beta 1 induced tra 31.7
438150 AA037534 Hs.300878 ESTε, Moderately εimilar to TGR3.HUMAN TGF-BE 31.6 430468 NM.004673 Hs.130699 ESTs 31.5
453060 AW294092 Hs.21594 ESTs 31.3
424206 NM.003734 Hs.198241 amine oxidase, copper containing 3 (vascular 30.8
422126 AW973784 Hs.112028 Misshapen/NIK-related kinase 30.5
406082 S47833 Hs.82927 adenosine monophosphate deaminase 2 (iεoform 30.3
421639 NM 012082 Hs.297921 Homo εapieπs mRNA full length insert cDNA clo 30.3
402520 29.9
418043 AW377752 Hs.83341 H.sapienε mRNA for tyroεine kinase rxeptor 28.7
443906 AA348031 Hs.7913 ESTε 29.7
450958 AL137669 Hs.25700 Homo εapienε mRNA; cDNA DKFZp434M0435 (from c 29.4
418828 AF020774 Hs.88844 Homo sapiens hair and skin epidermal-type 12- 29.4
412828 AL133396 Hs.74621 prion protein (p27-30) (Creutzfeld-Jakob dise 29.4
429507 NM.003102 Hs.2420 superoxide dismutase 3, extracellular 29.2
400545 29.1
425078 NM 002599 Hs.154437 phosphodiesterase 2A, cGMP-stimulated 29.1
429942 AI338993 Hs.134535 ESTε 28.9
438303 AB028998 Hs.6147 KIAA1075 protein 28.7
419971 AA400027 Hs.296234 ESTs, Highly similar to mitogen-xtivated pro 28.7
443060 D78874 Hs.8944 procollagen C-endopeptidase enhancer 2 28.7
452877 AI250789 Hs.32478 ESTs 28.6
412442 AI983730 Hs.26530 serum deprivation response (phosphatidylserin 28.6
424378 W28020 Hs.184367 GTPase xtivating protein-like 28.6
421823 N40850 Hs.28625 ESTs 27.9
447786 BE620810 Hs.39619 hypothetical protein LOC57333 27.6
400023 AFFX control: 18S ribosomal RNA 27.5
453874 AW591783 Hs.36131 collagen, type XIV, alpha 1 (unduliπ) 27.2
414134 X60188 Hs.861 mitogen-activated protein kinase 3 27.1
428451 AW970451 Hs.98570 ESTs 26.9
435520 AA297990 Hs.9315 HNOEL-iso protein 26.6
437179 AA393508 Hs.171409 serologically defined coton cancer antigen 8 26.4
441481 AA935303 Hs.270553 ESTs 26.0
450227 BE388192 Hs.78521 Homo sapienε cDNA: FLJ21193 fis, clone COL001 25.6
403731 25.5
452814 AI092790 Hs.55016 hypothetical protein FLJ21935 25.5
410036 R57171 Hs.57975 calsequestrin 2, cardix muscle 25.5
416854 H40164 Hs.80296 Purkinj'e cell protein 4 25.4
418421 R58620 Hs.85050 phospholamban 25.4
407000 U12139 gb:Human alpha1(XI) collagen (COL11A1) gene, 25.3
421803 NM 012205 Hs.108441 3-hydroxyanthranilate 3,4-dioxygenase 25.3
445613 BE550889 Hε.158491 ESTs 25.1
432302 AA345857 Hs.274307 KIAA1442 protein 24.8
420796 L34355 Hs.99931 sarcoglycan, alpha (50kD dystrophin-assxiate 24.8
423720 AL044191 Hs.23388 Homo sapienε cDNA: FLJ21310fis, clone COL021 24.7
417302 BE245812 Hs.8941 ESTs 24.6
421913 AI934365 Hs.109439 osteoglycin (oεteoinductive fxtor, mimxan) 24.6
440130 AI083899 Hs.157527 ESTs 24.5
431967 AJ243653 Hs.283404 organic cation transporter 24.5
424580 AA446539 Hs.35092 ESTs 24.4
406907 Z25427 gb:H.sapiens protein-serine/threonine kinase 24.2
443745 AB039670 Hs.9728 ALEX1 protein 24.1
429101 AW452174 Hs.173780 ESTs 23.5
410691 AW239226 Hs.65450 reticulon 4 23.4
408853 AW291484 Hε.254967 ESTε 23.3
407979 AA046306 Hs.62927 ESTε 23.1
448619 AI867182 Hs.202255 ESTs 22.8
424585 AA464840 gb:zx43h11.r1 Soares_total_fetus_Nb2HF8_9w Ho 22.7
407891 AA486620 Hs.41135 Endomucin 2 22.6
407196 D11747 Hε.177415 Finkel-Biskis-Reilly murine sarcoma virus (FB 22.5
426990 AL044315 Hε.173094 Homo sapiens mRNA; cDNA DKFZp564H142 (from cl 22.5
450493 M93718 Hs.166373 nitric oxide synthase 3 (endothelial cell) 22.1
420120 AL049610 Hs.95243 transcription elongation fxtor A (Sll)-like 22.0
423690 AA329648 Hε.23804 ESTs 22.0
402865 21.9
417387 AW021102 Hs.21509 ESTs 21.9
456898 NM 001928 Hs.155597 D component of complement (adipsin) 21.9
459722 Homo sapienε cDNA: FU23449 fis, clone HSI058 21.8
422927 AW247388 Hs.301423 calcium binding protein 1 (calbrain) 21.8
402195 21.7
418213 AW978753 Hs.127327 ESTs 21.6
440274 R24595 Hs.7122 scrapie responsive protein 1 21.6
455818 AI733747 gb:zπ86d04.y5 Stratagene lung carcinoma 93721 21.4
420861 AI039044 Hε.88827 Homo sapienε mRNA for FU00033 protein, parti 21.4
405228 21.3
441292 AF131218 Hε.7765 chromosome 16 open reading frame 5 21.3
432553 AA553334 Hs.211095 ESTs 21.3
417098 AB017365 Hs.173859 frizzled (Drosophila) homolog 7 21.2
453642 AI370936 Hs.34074 dipeptidylpeptidaseVI 21.2
405313 21.1
410243 D83402 Hs.289006 ESTs, Weakly similar to alternatively spliced 21.1
413186 AU077141 Hε.75231 εolute carrier family 16 (mon∞arboxylic acid 21.1
425954 AKO00633 Hs.164476 hypothetical protein FLJ20626 21.0
421770 AA374192 ■ Hs.108124 ribosomal protein L41 21.0
435265 AA779958 Hs.185932 ESTs 20.8 430036 AL050284 Hs 227782 DKFZP586M1019 protein 207
430233 AW367902 Hs 236443 Homo sapiens mRNA, cDNA DKFZp564N1063 (from c 207
436130 AA341497 Hs 31408 ESTs 207
434843 R43707 Hs 133159 ESTs Weakly similar to PIHUSD salivary proli 207
429303 AW137635 Hs 44238 ESTs 206
442422 AI344415 Hs 156082 ESTs 205
410399 BE068889 Hs 63236 εynuclem, gamma (breast cancer spxific prot 20 5
435869 AF255910 Hs 54650 ESTs, Weakly similar to (defliπe not availabl 205
447384 AI377221 Hs 40528 ESTs 205
440610 AI733098 Hs 130800 ESTs 205
445806 AL137516 Hs 13323 hypothetical protein FLJ22059 204
433657 AI244368 Hs 8124 PH domain containing protein in retina 1 204
436467 AW450278 Hs 91681 ESTs 203
440191 AI990417 Hs 116107 Homo sapienε genomic DNA chromosome 21q, sx 202
417511 AL049176 Hs 82223 chordm like 202
406976 M60299 gb Human alpha-1 collagen type II gene, exons 20 1
443547 AW271273 Hs 23767 ESTs 20 1
417998 AW967420 gb EST379495 MAGE resequences, MAGJ Homo sapi 20 1
419313 AA843387 Hs 87279 ESTs 201
408322 AW181985 Hs 249986 ESTs 200
448422 BE263813 gb 601194177F1 NIH.MGC.7 Homo sapiens cDNA cl 200
403121 19 9
424198 AB029010 Hs 143026 KIAA1087 protein 19 9
459060 H89244 Hs 79625 heterogeneous nuclear ribonuclxproteiπ D (AU 199
457829 AI742291 Hs 210843 ESTs, Weakly similar to dJ1039K52 [H sapiens 199
445029 AF196481 Hs 12256 midline 2 199
424362 AL137646 Hs 146001 Homo sapiens mRNA, cDNA DKFZp586F0824 (from c 198
417067 AJ001417 Hs 81086 solute earner family 22 (extraneuronal monoa 197
413972 BE279548 Hs 162717 ESTs, Weakly similar to HPPD.HUMAN 4-HYDROXYP 196
435891 AW249394 Hs 5002 copper chaperone for superoxide dismutase 196
447551 BE066634 Hs 929 myosin, heavy polypeptide 7, cardix muscle, 196
400637 195
409882 AJ243191 Hs 56874 heatshxk 27kD protein family, member 7 (car 194
430310 U60115 Hs 239069 four and a half UM domains 1 194
402741 194
401703 193
409229 H60333 Hs 251928 nuclear pore complex interacting protein 19 3
453856 AA804789 Hs 19447 Homo sapienε mRNA for FU00106 protein, parti 193
430342 NM.005938 Hs 239663 myeloid/lymphoid or mixed lineage leukemia (t 19 3
404033 19 2
411939 AI365585 Hs 146246 ESTs 192
431227 X63755 Hs 2743 keratin, cuticle, ultrahigh sulphur 1 191
452669 AA216363 Hs 262958 ESTs, Weakly similar to alternatively spliced 19 1
439698 AW779654 Hε 55876 ESTs 189
416253 BE250659 Hε 15463 ESTs 189
418556 T02850 gb FB12A9 Fetal brain, Stratagene Homosapien 189
408877 AA479033 Hs 130315 ESTs 189
415994 NM 002923 Hs 78944 regulator of G-protein signalling 2, 24kD 189
417054 AF017060 Hs 174151 aldehyde oxidase 1 188
404654 188
420174 AI824144 Hs 23912 ESTs 188
400625 187
406150 187
457835 BE256338 Hs 192375 ESTs, Highly similar to dJ127B203 (H sapiens 186
420105 AW015571 Hs 32244 ESTs 186
404619 BE514535 Hs 77171 minichromosome maintenance deficient (S cere 185
423282 AL137563 Hs 126378 putative ABC transporter 185
424097 M13981 Hε 1734 inhibin, alpha 185
448543 AW897741 Hs 21380 Homo sapienε mRNA, cDNA DKFZp586P1124 (from o 185
427605 NM.000997 Hs 179779 πbosomal protein L37 184
406535 184
418947 W52990 Hε 22860 ESTs 184
414323 NM.014759 Hs 239500 KIAA0273 gene product 183
457111 AA482027 Hs 142569 ESTs 183
418373 AW750770 Hs 84344 CGI-135 protein 183
424461 D83542 Hs 148090 cadhenn 15, M-cadhenn (myotubule) 182
451565 NM.000897 Hs 456 leukotriene C4 synthase 182
407751 BE276096 Hs 38205 from HeLa cyclm-dependent kinase 2 interxti 18 2
432031 AF039196 Hs 284126 hairteεs (mouεe) homolog 181
404608 H58589 Hs 35156 Homo sapiens cDNA FU11027 fis, clone PLACE10 181
451962 AW078832 Hs 226806 ESTs 18 1
424100 AI793080 Hs 123525 ESTs, Weakly similar to NGAL RAT NEUTROPHIL G 18 1
451509 AI969529 Hε 171637 Homo sapiens cDNA FU21937 fis, clone HEP044 18 1
453512 AL040160 Hε 209542 ESTs, Weakly similar to B cell linker protein 180
429924 W39693 Hε 226138 Homo sapiens mRNA, cDNA DKFZp566H2446 (from c 179
423780 AA352013 gb EST59935 Infant brain Homo sapiens cDNA 5' 179
427030 AA397600 Hε 97531 ESTs 179
439872 T81058 gb yd26c08 r1 Soareε fetal liver εpleen 1NFLS 179
407836 T79340 Hε 22575 Homo sapiens cDNA FU21042 fis, clone CAE112 179
451427 AI091441 Hs 26401 tumor nxrosis fxtor (ligand) superfamily, 179
424462 AU076666 Hs 148101 serum constituent protein 179
451533 NM 004657 Hs 26530 serum depnvation response (phosphatidylseπn 178
422319 AW403342 Hs 115232 splicing factor 3a subunit 2, 66kD 178 400489 178
454421 BE409759 Hs 59563 Homo sapiens mRNA for FU00007 protein, parti 178
449282 AL048056 Hs 23437 Homo sapiens cDNA FLJ13555 fis, clone PLACE10 177
420495 AI338247 Hs 98314 Homo sapiens mRNA, cDNA DKFZp586L0120 (from c 177
429790 AK001352 Hs 221737 hypothetical protein FU10490 177
422796 AW897265 gb CM0 NN0057-150400-335-a04 NN0057 Homo sapi 177
427980 AA418305 gb zv96g05 s1 Soares.NhHMPu.S1 Homo sapiens c 176
408543 AW410200 gb fh05b12 x1 NIH MGC 17 Homo sapienε cDNAcl 176
440206 AI762232 Hs 46794 ESTs 176
455904 BE156173 gb QVO HT0367-201299-079-a02 HT0367 Homo sapi 175
427707 NM 005578 Hs 180398 UM domain-containing preferred transtocation 175
437140 AA312799 Hs 283689 xtivator of CREM in testis 175
417637 AA204969 Hs 234863 Homo εapiens cDNA FLJ12082fis, clone HEMBB10 175
419171 NM 002846 Hs 89655 protein tyrosine phosphatase, rxeptor type, 174
417808 AF177909 Hε 12828 tweety (Drosophila) homolog 1 174
426232 Z70024 Hs 168157 nuclear transcnption fxtor Y, gamma 174
440747 AW297226 Hs 137840 ESTε, Moderately similar to SIX1.HUMAN HOMEOB 174
415307 F05232 Hε 27495 prostate cancer assxiated protein 7 173
407049 X72632 (NONE) 173
454054 AI336329 Hs 301519 Homo εapiens cDNA FU 12536 fis, clone NT2RM40 173
411085 AF022991 Hs 68398 peπod (Drosophila) homolog 1 173
443104 AA088470 Hs 83135 p53-responsιve gene 6 172
424106 AA412442 Hs 98132 ESTε 172
446716 AA436575 Hs 16602 ESTs 171
448677 AI560769 Hs 227051 ESTs 170
434919 AI821740 Hε 116531 ESTε 170
401171 AA360954 Hs 27268 Homo sapiens mRNA, cDNA DKFZp564N196 (from cl 170
456804 AI421645 Hs 139851 caveolm 2 170
453621 AW749983 gb QV3-BT0537-280100-07 e04 BT0537 Homo sapi 169
413419 BE093686 Hs 48938 Homo sapiens cDNA FU21802fis, clone HEP007 169
426515 BE394222 Hs 231444 ESTs 169
428937 T82221 Hs 56729 lymph∞yte-spxmc protein 1 169
424562 AI420859 Hs 150557 basic transcnption element binding protein 1 169
444655 AF088886 Hs 11590 cathepsin F 169
447424 AI681105 Hs 181641 ESTs 168
425439 D38024 Hs 157425 double homeobox, 2 168
446707 AI591214 Hs 156336 ESTs 168
405324 168
434340 AI193043 Hs 128685 ESTs 168
422942 AF054839 Hs 122540 telraspan 2 168
421820 AW662990 Hs 108675 heme binding protein 168
420037 BE299588 Hs 135569 ESTs, Weakly similar to NEUROD (H sapiens] 167
428818 AI131291 Hs 98866 ESTs 167
426485 NM.006207 Hs 170040 platelet-deπved growth factor receptor-like 167
404947 166
412677 AW029608 Hs 17384 ESTs 166
401551 166
408053 AW139474 Hs 246862 ESTs 166
425016 AA376049 Hs 154162 ADP-πbosylation fxtor-like 2 166
418179 X51630 Hs 1145 Wilmε tumor 1 166
418994 AA296520 Hs 89546 Selxtin E (endothelial adhesion molxule 1) 165
457514 AA775208 Hs 136423 ESTs 165
426275 BE151551 gb RCO-HT0297-201199-031-f12 HT0297 Homo sapi 165
457924 AL390142 Hs 288697 Homo sapiens cDNA FU13861 fiε, clone THYRO10 165
430712 AW044647 Hs 196284 ESTε 165
455144 AW875942 gb CM1-PT0013-131299-067-b10 PT0013 Homo sapi 164
407524 X64985 gb H sapiens mRNA HTPCRX11 forolfxtory rece 164
426712 AW173177 Hs 197755 ESTs 164
429954 AI918130 Hs 21374 ESTs 164
446208 BE258323 Hs 225795 ESTs, Highly similar to OTX1.HUMAN HOMEOBOX P 164
442792 AI352340 Hs 131194 ESTs 163
420485 AF218586 Hs 288835 cell death-inducing DFFA-like effector b 163
426767 AA384398 Hs 192491 ESTs 163
436950 L05779 Hs 113 epoxide hydrolase 2, cytoplasmic 163
415196 AK000150 Hε 78185 MAX-like bHLHZIP protein 163
442197 AW837912 gb QV3-LT0048-260100-068-C02 LT0048 Homo sapi 163
433457 AA830194 Hs 199417 Homo sapienε mRNA for FU00027 protein, parti 162
402316 162
409736 AA078628 gb 7P07H07 Chromosome 7 Plxental cDNA Ubrar 162
407964 AW130334 Hs 281111 ESTs 162
433677 AI791912 Hs 190885 ESTs, Moderately similar to ALU1.HUMAN ALU SU 162
425507 AI684745 Hs 165983 hypothetical C2H2 zinc finger protein FU2250 162
413724 AA131466 Hs 23767 Homo sapiens cDNA FU12666 fis, clone NT2RM40 162
408922 R87388 gb ym88g04 r1 Soareε adult brain N2b4HB55Y Ho 161
413055 AV655701 Hε 75183 cytochrome P450, subfamily HE (ethanol-induc 161
435977 AL138079 Hs 5012 brain specific membrane-anchored protein 161
442208 AW296984 Hs 255595 ESTε, Weakly similarto PSF.HUMAN PTB-ASSOCIA 161
402426 160
412399 N53816 Hs 14394 hypothetical protein FU20157 160
413200 AA127395 Hs 222414 ESTs 160
404597 159
453143 AA382234 Hs 170121 protein tyrosine phosphatase, rxeptor type, 159
455984 BE177442 gb RC1-HT0595-200400-012-f01 HT0595 Homo sapi 159 416193 T25400 gb PTHI069 HTCDL1 Homo sapiens cDNA 573' sim 159
407065 Y10141 gb H sapiens DAT1 gene, partial, VNTR 159
441785 AW138139 Hs 244598 ESTs 159
413784 BE165819 gb CM0-HT0486-220300-301-d12 HT0486 Homo sapi 159
429092 AI190864 Hs 178226 ESTs, Weakly similar to ALU1.HUMAN ALU SUBFAM 158
408499 AW205323 Hs 253475 ESTs 15 8
453754 AW972580 Hs 172753 ESTs 158
450826 U43030 Hs 25537 cardiotrophm 1 158
428486 AW583497 Hs 184604 pancreatic polypeptide 157
405895 157
409108 AA339443 Hε 48793 ESTs 157
423334 AK000906 Hs 127273 hypothetical protein FU10044 156
422948 AW810824 Hs 21351 ESTs 156
447852 AW504781 gb UI-HF-BNO-aln-o-04-O-UI r1 NIH.MGC.50 Homo 156
419084 AA496539 Hs 179902 transporter-like pratem 156
456771 AW016739 Hs 232201 ESTs 156
438564 AA381553 Hs 198253 major histocompatibility complex, class II, D 156
448705 H05072 Hs 124984 ESTs, Moderately similar to unnamed protein p 156
454460 X66945 Hs 48 fibroblast growth fxtor rxeptor 1 (fms rela 15 5
458893 BE161733 Hs 97283 ESTε, Weakly εimilar to ALU1.HUMAN ALU SUBFAM 155
426759 AI590401 Hs 21213 ESTs 155
453769 R35261 Hs 24947 ESTs 154
434179 AI743448 Hs 116177 ESTs 154
404111 154
402056 154
458602 AI262208 Hs 276489 ESTs 153
427530 AA405093 Hs 126519 ESTs 153
414716 AF199598 Hs 97044 Kv channel interacting protein 2 153
400632 153
443918 AA305475 Hs 22660 Homo sapiens cDNA FLJ11658 fis, clone HEMBA10 153
432037 AW450592 Hs 300459 ESTs 153
412921 BE009345 Hs 128942 ESTs 153
421905 AI660247 Hs 32699 ESTs, Weakly similar to UV-1 protein (H sapi 153
441704 AI458766 Hs 201988 ESTs 153
414272 AI651603 Hs 46988 ESTs 153
448224 R48700 Hs 20733 EH-domam containing 2 152
404611 H58589 Hs 35156 Homo sapiens cDNA FU11027 fis, clone PLACE10 152
448381 D61580 Hs 21036 Homo εapienε mRNA, cDNA DKFZp434A1010 (from c 152
454719 BE006547 gb RC2 BN0130-040400-011-b03 BN0130 Homo sapi 152
446973 H95724 Hs 4283 ESTs 152
457760 AA668123 Hs 134170 ESTs 152
440144 AW082297 Hs 88523 ESTs 152
407387 AB000895 gb Homo sapienε mRNA for cadhenn FIB1, parti 152
427850 AA416756 Hs 161051 ESTs, Moderately similar to ALU6.HUMAN ALU SU 152
404244 151
402959 151
435487 W07343 Hs 182538 phospholipid εcramblase 4 151
414213 BE297765 gb 601176246F1 NIH MGC 17 Homo sapiens cDNA c 150
455916 BE156710 gb QV0-HT0368-310300-181-d01 HT0368 Homo sapi 150
448943 AI608810 Hs 193288 ESTs 150
418026 BE379727 Hs 83213 fatty xid binding protein 4, adipxyte 150
454082 AF283508 Hs 63168 cell death regulator aven 149
453308 AW959731 Hs 32538 ESTs 149
458823 AW207574 Hs 179501 ESTs 149
452532 AI905811 Hs 110757 DNA segment on chromosome 21 (unique) 2056 ex 149
418464 R87580 gb ym89h07 r1 Soares adult brain N2b4HB55Y Ho 149
409473 AL137716 Hs 296567 Homo sapiens mRNA, cDNA DKFZp434D2030 (from c 148
449779 AA004258 Hs 25218 ESTs, Weakly similarto ALUB HUMAN mi ALU C 148
457546 AA568484 Hs 153632 ESTs 148
403368 148
432163 AK000440 Hs 272799 hypothetical protein FLJ20433 148
421531 AA713505 Hs 291769 ESTs 148
428283 AI439096 Hs 25832 Homo sapienε mRNA, cDNA DKFZp564P116 (from cl 148
443528 AK001778 Hs 9547 hypothetical protein FU10916 148
402399 148
410545 U32324 Hs 64310 interleukin 11 rxeptor, alpha 148
450300 AL041440 Hs 58210 ESTε 148
403552 147
406929 U04690 gb Human olfactory rxeptor (OR17-210) gene, 147
436365 AW444548 Hs 163118 ESTs 147
402550 147
441782 AW140126 Hs 132357 ESTs 147
415672 N53097 Hs 193579 ESTs 147
430582 AI215509 Hs 143964 ESTs 147
425770 NM.014363 Hs 159492 spastic ataxia of Chadevoix-Saguenay (sacsin 147
432683 AW995441 Hs 10475 ESTs 147
441871 AI306150 Hs 153450 ESTs, Weakly similar to 1909123A Na glucose c 146
447481 AF052151 Hs 18686 Mouse Mammary Turmor Virus Receptor homolog 146
405114 146
401082 146
454316 AW366144 gb QVO-HT0101-061099-032 b12 HT0101 Homo sapi 146
421572 AA531607 Hs 125143 ESTs, Weakly εimilar to POL2 MOUSE RETROVIRUS 146
424591 R55704 Hs 150968 hyp∞retiπ (orexm) rxeptor 1 146 441503 AW172263 Hs 185202 ESTs 146
416199 R83537 gb yq12a08 r1 Soares fetal liver spleen 1NFLS 146
420360 U83171 Hs 97203 small inducible cytokine subfamily A (Cys Cys 146
425126 N32759 Hs 172944 chorionic goπadotropin, beta polypeptide 145
417421 AL138201 Hs 821 0 nuclear receptor subfamily 4, group A, member 145
405100 145
454012 M76424 Hs 37014 carbonic anhydrase VII 145
402457 145
454613 AW810814 gb MR2-ST0129-201099 004-e01 ST0129 Homo sapi 145
429821 AL096749 Hs 225433 Homo sapiens mRNA, cDNA DKFZp434G153 (from cl 145
431073 BE254470 Hs 249186 cone rod homxbox 145
421143 AB024536 Hs 102171 immunoglobulin superfamily containing leucine 145
401223 144
438627 AI087335 Hs 123473 ESTs 144
407124 R08160 Hs 268857 ESTε, Weakly similar to ALU1 HUMAN ALU SUBFAM 144
437217 AW779241 Hs 155316 ESTs 144
427627 R87582 Hs 179915 guanine nucleotide binding protein (G protein 144
410258 X52638 Hs 739 6-phosphofructo-2-kinase/fructose-2,6-biphosp 144
413237 AI468574 Hs 171965 ESTs 144
412975 T70956 Hs 75106 clusteπn (complement lysis inhibitor, SP40, 144
426488 X03350 Hs 4 alcohol dehydrogenase 2 (class I), beta polyp 144
416667 AK000526 Hs 79457 hypothetical protein FLJ20519 144
405479 143
418432 M14156 Hs 85112 insulin-like growth factor 1 (somatomedia C) 143
426316 NM.002430 Hs 301852 Human DNA sequence from clone 437G10 on chram 143
412171 AW897452 gb CMO-NN0058-150400-337-b08 NN0058 Homo sapi 143
447241 BE382838 Hs 19322 ESTs 143
402100 142
438286 AW139266 Hs 134807 Homo sapiens cDNA FLJ12057 fis, clone HEMBB10 142
407947 AI500332 Hs 102367 ESTs, Weakly similar to hTcf-4 [H sapiens] 142
402275 142
402358 142
439624 AA838771 Hs 124407 ESTs 142
444455 AI149879 Hs 175024 Homo sapiens cDNA FU23447 fis, clone HSI033 142
455314 Y17114 Hs 73393 eyes absent (Drosophila) homolog 4 142
427872 AA835058 Hs 21111 ESTs 142
409826 AW501112 Hs 34487 hypothetical protein FU23412 142
414002 NM.006732 Hs 75678 FBJ munne osteosarcoma viral oncogene homolo 142
442682 AI014545 Hs 231027 EST 14 1
457033 AF029674 Hs 173422 KIAA1605 protein 14 1
410480 R97457 Hs 63984 cadhenn 13, H-cadheπn (heart) 14 1
401007 14 1
458274 AF149297 Hs 8087 NAG-5 protein 14 1
454106 D19687 Hs 245146 ESTs 14 1
432928 AA570454 Hs 186467 ESTs, Moderately similar to ALU1.HUMAN ALU SU 14 1
425352 NM 000939 Hs 1897 proopiomelanocortm (adreπxorticotropin/ bet 14 1
433887 AW204232 Hs 279522 ESTs 141
434927 H46612 Hs 293815 ESTs, Weakly similar to PLM.HUMAN PHOSPHOLEMM 14 1
404282 14 1
422581 NM 016339 Hs 118562 Link guanine nucleotide exchange factor II 140
424823 NM 006226 Hs 153322 phospholipase C, epsilon 140
408107 AA806754 Hs 62835 ESTs 140
401577 140
433883 AI925688 Hs 222312 ESTs, Weakly similar to B24264 prolme-πch p 140
408104 AW972927 Hs 293968 ESTs 140
404642 140
400675 140
406059 140
448386 AB037750 Hs 21061 KIAA1329 protein 140
407287 AI678812 Hs 201658 ESTs, Weakly similar to ALU4.HUMAN ALU SUBFAM 140
TABLE 22B
Pkey Unique Eos probeset identifier number CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT number Accession
408922 1090171 R87388 R84328AA058916
409543 11387231 AW410200 AW409705AW411433 BE296786 BE270309
409736 1151891 AA078628 R09051 AA078197 AA077334 AW748808 AW748807
412171 12807591 AW897452 Z20302 D55805 D52877 D60432
413784 13891501 BE165819 BE165853 W01386
414213 14263751 BE297765 BE262061 BE302686 T83915
416193 1577102 T25400 H26834 H44554 R73193
416199 15775611 R83537 W80940 H27368
417998 1713751 AW967420 AA210915 AA236991 AA210916
418464 1759038 -2 R87580
418556 1767866 -1 T02850
422796 221500 ϊ AW897265 AW897274 AL119504 AW897275 AW897270 AW897312 AW897318 AW897317 AA317240 AW361361
T06241 AA326794 AL138130 AW407975 AW989277
423780 231952.1 AA352013 AA330878 AA339379 AW966303 424585 241151 1 AA464840 AA343628
426275 2637121 BE151551 AA373783 BE182852 BE008826 BE008827 BE008781 BE008699
427980 2852251 AA418305 AI264351
439872 47823.1 T81058 AL357200 T70270
442197 5355501 AW837912 AW837934 AA984475 AW997490
447852 739731 AW504781 BE620394
448422 7627701 BE263813 BE253504AI500202 BE251145
453621 9745261 AW749983 AL045823
454316 11093501 AW366144AW366154AW366142AW366151 AW366140AW366155 BE141715 BE141718 BE141698 0 454613 1226904.1 AW810814 AW810787 AW810854 AW810773 AW810735 AW810785 AW810660 AW810834 AW810874 AW810723
AW810881 AW810791 AW810644 AW810659 AW810676
454719 12306461 BE006547 AW815578 AW815311 AW856304
455144 12549141 AW875942 AW858234 AW875938 AW875941 AW858235 AW875958
455818 1372191 AI733747 AA129802 5 455904 13822901 BE156173 BE156305 BE156196
455916 13827481 BE156710 BE156726 BE156712
455984 13972881 BE177442 BE177439 BE177445 BE177440 BE177448 BE177444 BE177433
TABLE22C 0
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495 Strand Indicates DNA strand from which exons were predicted 5 NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400489 8954013 Plus 131475-131652 0 400545 9800107 Minus 124618-124881
400625 7228177 Minus 117266-117441
400632 3818355 Plus 72875-73447,75874-76425
400637 8894326 Plus 68901-69507
400675 8118750 Plus 11223-11816 5 401007 8117333 Minus 140821-141050
401082 3242744 Plus 22937-23494,27677-27966
401223 8099088 Plus 148940-150214
401551 8096896 Minus 189824-190728
401577 9280797 Minus 139377-139674,141195-141281,142217-142340 0 401703 4826475 Plus 135-1229
402056 8084234 Plus 207002-207288
402100 8117697 Plus 133649-133792
402195 7689778 Minus 147901-148884
402275 2935596 Minus 31065-31233,33680-33771,34345-34411,3889039125,39779-39943 5 402316 7527774 Minus 10751-10919,18817-19052,22131-22328
402358 8886976 Minus 131788-132729
402399 1905915 Minus 24502-24666,24986-25102
402426 9796361 Minus 73590-73824
402457 9796782 Minus 16513-16577,16838-16926 0 402520 7596899 Minus 171761-171996
402550 7652009 Minus 80413-80673
402741 9212200 Minus 18603-18760,19719-19890
402865 9716300 Plus 3197-3429,3722-3914,5795-5987,6802-6961,8653-8815,9292-9660
402959 9368493 Plus 36729-37084 5 403121 9180223 Plus 4059-4258
403368 4388738 Plus 70286-70429,75165-75258
403552 6862638 Minus 117504-117662
403731 7543752 Minuε 144000-144618
404033 8122195 Plus 7976-8156 0 404111 9408736 Plus 161506-161781
404244 5672609 Minus 98173-98517
404282 2276311 Plus 61503-62205
404597 9958262 Minus 114369-114599
404642 9796810 Plus 102999-103145 5 404654 9797010 Plus 6275-6527
404947 7382205 Plus 29740-30105,30176-30412
405100 8076846 Plus 144114-144234
405114 8096938 Minus 97013-97560
405228 7248990 Plus 92234-95905
70 405313 3638954 Plus 68924-69093
405324 3342751 Minus 5475-5677
405479 6453391 Plus 1668-1844
405895 7677903 Minus 66990-67484
406059 9103984 Minus 13856-14004
75 406150 9886026 Minus 59331-59701
406535 7711477 Plus 83135-83362
o O TABLE 23A 626 genes upregulated in utenne cancer relative to normal body tissues
Table 23A lists about 626 genes upregulated in utenne cancer relative to normal body tissues that are likely to encode proteins amenable to modulation by small molxules, peptides, or antibodies These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expression data for each probeset obtained from this analysis was expresεed aε average intensity (Al), a normalized value reflxting the relative level of mRNA expression The protein products of these genes often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molecules, peptides, or antibodies (e g pkinase, death-domain, 7tm, phosphatase, or lon.transporter) Certain predicted protein domains are noted Pkey Unique Eos probeset identifier number
ExAccn Exemplar accession number, GenBank accesεion number
UniGenelD UniGene number
Pred Prot Domainε Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30 276 280) UniGene Title UniGene gene title
R1 95th percentile of uterine cancer Als divided by the 50th percentile of normal tissue Als, where the 10th percentile of all normal tissue Als was subtrxted from both the numerator and denominator Pkey, ExAccn, UnigenelD, Unigene Title, Pred ProtDomains, R1
Figure imgf000271_0001
418113, AI272141, Hs 83484, SRY (sex determining region Y) box 4, HMG_box,homeobox,TM=M,SS=N, 938 412791, AI131192, Hs 143199, ESTs, Weakly similar to S72481 probable , pkinaεe.PBD.none, 936 432435, BE218886, Hs 282070, ESTs, none.none 9 35 416530, U62801, Hs 79361 kallikrein 6 (neurosin zyme), trypsιn,TM=M,SS=M, 932 439018, AW300887, Hs 26638 membrane spanning 4-domaιnε, subfamily A none,TM=Y,SS=M, 923
445537, AJ245671 Hs 12844, EGF-like domain, multiple 6, EGF.MAM,, 9 19 410407, X66839, Hs 63287, carbonic anhydrase IX carb anhydrase,TM=M,SS=M, 9 19 417165, R80137, Hs 302738 Homo sapienε cDNA FLJ21425 fis, clone C, Sulfatejransp STAS HMG.box, 9 17 453459, BE047032, Hs 257789, ESTs, none.none, 9 14 431674, AA098901, Hs 301642, G-protein coupled receptor; none.GCV.H, 905
418004, U37519, Hs 87539, aldehyde dehydrogenase 3 family, member , aldedh,TM=M,SS=M, 900 413278, BE563085, Hs 833, interferon stimulated protein, 15 kDa, ubiquitin,, 893 436954, AA740151, Hs 130425, ESTs, none.none, 891
420344, BE463721, Hs 97101, putative G protein-coupled rxeptor; Methyltransf_5,TM=Y,SS=M, 8 89 425397, J04088, Hs 156346, topoisomerase (DNA) II alpha (170kD), DNA_gyraseB DNA_topoιsolV,HATPase_c„ 8 85
407792, AI077715 Hs 39384, putative secreted ligand homologous to f, none TM=M SS=Y, 880 451027, AW519204, Hs 40808, Homo sapienε, Similar to RIKEN cDNA 2810, none.none, 879 422809, AK001379, Hs 121028, hypothetical protein FU10549, IQ,TM=M,SS=N, 872 413385, M34455, Hs 840, indoieamme-pyrrole 2,3 dioxygenase, IDO,TM=M,SS=N, 870 444784, D12485, Hs 11951, xtonucleotide pyrophosphatase/phosphodi, Somatomedιn_B,Endonuclease,Phosphodιest,TM=Y,SS=M, 869
421502, AF111856, Hs 105039, solute carrier family 34 (sodium phospha, Rιbosomal_L20 Na_Pι_cotrans,TM=Y,SS=N, 867 437935, AW939591, Hs 5940, mucin 13, epithelial transmembrane, EGF,SEA,TM=Y,SS=M, 8 56 408692, AL040127, Hs 34074, dipeptidylpeptidase VI, DPPIV_N_term,Peptιdase_S9,none, 855 414812, X72755, Hs 77367, monokine induced by gamma interferon, IL8,TM=M,SS=Y, 853 428187, AI687303, Hs 285529, G protein-coupled rxeptor 49, 7tm_1,none, 849
448672, AI955511, Hs 374290, ESTε, lιg_chan,ANF_rxeptor,SBP_bac_3,TM=Y,SS=M, 844 425776, U25128, Hs 159499, parathyroid hormone receptor 2, 7tm_2,HRM,TM=Y,SS=M, 840 443426, AF098158, Hs 9329, chromosome 20 open reading frame 1, none,TM=M,SS=N, 840 452093, AA447453, Hs 27860, Homo sapiens mRNA, cDNA DKFZp586M0723 (f, 7tm_1 ,πone, 8 33 407894, AJ278313, Hs 41143 phospho ositide specific phospholipase , C2,PI-PLC-Y,PI PLC-X TM=M SS=N, 8 23
409799, D11928, Hs 76845, phosphoseπne phosphatase like, Hydralase,TM=M,SS=N, 821
419508, AW997938, Hs 90786, ATP-binding cassette, sub-family C (CFTR, ABC_traπ,ABC_membrane,TM=Y,SS=M, 820 424441, X14850, Hs 147097, H2A histone family, member X, histone.CBFD.NFYB.HMF,, 820 408243, Y00787, Hs 624, interleukin 8, HLH,PAS,IL8,TM=M,SS=N, 800 5 415752, BE314524, Hs 78776, putative transmembrane protein, none,TM=Y,SS=N, 799
422608, AW160644, Hs 118695, potassium voltage-gated channel, subfa i, lon.trans.KJetra TM=Y,SS=N, 799 433001, AF217513, Hs 279905, clone HQ0310 PRO0310p1, none,, 795
409649, AA159216, Hs 55505, hypothetical protein FU20442, Y_phosphatase,DSPc,TM=M,SS=N, 795 _ 424078, AB006625, Hs 139033, paternally expressed 3, zf C2H2,KRAB,noπe, 786 0 432179, X75208, Hs 2913, EphB3, EPHJbd,fn3,pkmase,SAM,TM=Y,SS=M, 785
424581, M62062, Hs 150917, catenin (cadhenn assxiated protein), a, Vιnculm,DNAJιgase_ZBD,TM=M,SS=N, 784 420610, AI683183 Hs 99348, distal less homx box 5, homeobox,TM=M,SS=N, 781 436856, AI469355, Hs 127310, ESTε, pkinase.rrm TM=M,SS=N, 7 81 411125, AA151647, Hs 68877, cytochrome b-245, alpha polypeptide, none,TM=Y,SS=M, 7 80 5 407811 , AW190902, Hs 40098, cysteine knot superfamily 1 , BMP antagon, TGF-beta,DAN„ 778
424399, AI905687, Hs 348419, AI905687 IL-BT095-190199-019 BT095 Homo , none,TM=M,SS=M, 765 418836, AI655499, Hs 161712, ESTs, pkinase.Activin recp,PDZ,ZU5,death, 764 435793, AB037734, Hs 4993, KIAA1313 protein, none,TM=M,SS=N, 761 426201, AW182614, Hs 128499, ESTs, SH3,none, 759 O 447400, AK000322, Hs 18457, hypothetical protein FLJ20315, zf-C3HC4,TM=Y,SS=M, 755
410850, AW362867, Hs 302738, Homo sapienε cDNA FU21425 fis, clone C, Sulfate.transp.STAS.HMG.box, 755 453464, AI884911 , Hs 32989, rxeptor (calcitonin) activity modifying, noπe,TM=Y,SS=N, 754 417115, AW952792, Hs 334612, small nuclear ribonucleoprotein polypept, Sm.pkinase,, 7 52 437897, AA770561, Hs 146170, hypothetical protein FLJ22969, zf-DHHC,noπe, 738 5 443991, NM.002250, Hs 10082, potasεium intermediate/εmall conductance, CaMBD,SK_channel,ιon_tranε,TM=Y,SS=M, 736 414617, AI339520, Hε 288817, ESTs, Moderately similar to N Chain N, M, hexokιnase,hexokιnase2,TM=Y,SS=N, 735 422017, NM.003877, Hs 110776, STAT induced STAT ιnhιbιtor-2, SH2„ 733 424834, AK001432, Hs 153408, Homo sapienε cDNA FU10570 fis, clone NT, none.none, 730 409041, AB033025, Hs 50081, Hypothetical protein, XP.051860 (KIAA119, πone,TM=M,SS=M, 728 0 417078, U65580, Hs 81134, interleukin 1 rxeptor antagonist, IL1„ 728
429170, NM.001394, Hs 2359, dual specificity phosphatase 4, Rhodanese,DSPc,Y_phosphatase,Rιbosomal_S3_N,TM=M,SS=N, 728 418506, AA084248, Hs 372651, Unknown protein for MGC 29643 (formerly , none.none, 727
448913, AA194422, Hs 22564, myosin VI, rrm,zf-RaπBP,pkmxe,GST_C,Ets,SAM_PNT,ABC2_membrane,myosιn head,IQ,Myosιn_N,bZIP,zf- C2H2,PHD,BTB,TFIIS,AT hook,SAM,TM=M,SS=N, 726 5 409340, BE174629, Hs 321130, hypothetical protein MGC2771, aa_permeases,pyndoxal deC,bromodomaιn,PHD,MBD,AT_hook,DDT,PI3 PI4 kmase.FAT FATC,BolA,RUN,TM=M,SS=N, 726 424317, AI865032, Hs 26017, ESTε, none.pkmase, 721
410361, BE391804 Hs 62661, guanylate binding protein 1, interferon-, GBP.GBP C,TM=Y,SS=M, 721 428450, NM.014791, Hs 184339, KIAA0175 gene product, KA1,pkmase,TM=M,SS=N, 7 14 0 438707, L08239, Hs 5326, ammo xid system N transporter 2, porcu, ACAT,MBOAT,TM=Y,SS=M, 705
423011, NM.000683, Hε 123022, adrenergic, alpha-2C-, rxeptor, 7tm_1,TM=Y,SS=M 7 03 435021, AA922192, Hε 73962, ESTs, EPHJbd,pkιπase,fn3,SAM,none, 702 446163, AA026880, Hs 25252, prola in rxeptor, none.NA.NA, 701
447768, X86400, Hs 19520, FXYD domain-containing ion tranεportreg, ATP1G1_PLM_MAT8,TM=M SS=N, 700 5 439453, BE264974 Hs 6566 thyroid hormone rxeptor interactor 13, AAA,ABCJran,CoaE,TM=M,SS=N, 699
451035, AU076785, Hs 430, plastin 1 (I isoform), efhand,CH,Adaptιn_N„ 699 450581, AF081513, Hs 25195, TGF-beta 4, TGF-beta,TGFb_propeptιde„ 695 424054, AA334511 , Hs 26638, membrane spanning 4-domaιns, subfamily A, none,TM=Y,SS=M, 693 432519, AI221311, Hs 130704, ESTs, Weakly similar to BCHUIA S-100 pro, none.none, 693 0 436481, AA379597, Hs 5199, HSPC150 protein similarto ubiquitm-con, UQ_con,TM=M SS=N, 6 92
419693, AA133749, Hs 301350, FXYD domain containing ion tranεport reg ATP1G1 PLM.MAT8 TM=Y,SS=M, 6 92 437139, W73685 Hs 118513, ESTs, Weakly similarto RTA RAT PROBABLE, 7tm 1,TM=Y,SS=M 687 418054 NM 002318, Hs 83354, lysyl oxidase like 2, SRCR,Lysyl_oxιdase,TM=M,SS=M, 687 418203, X54942, Hs 83758, CDC28 protein kinase 2, CKS„ 686 410467, AF102546 Hs 63931, dachshund (Drosophila) homolog, Skι_Sno,TM=M,SS=M 686 425247, NM_005940, Hs 155324, matrix metalloproteinase 11 (stromelysin, hemopexιn,Peptιdase_M10„ 685 453064 R40334, Hs 89463, potassium large conductance calcium acti, none.none, 683 452046, AB018345, Hs 27657, KIAA0802 protein, none,TM=M,SS=N, 679
41 771, AA804698, Hs 82547, retinoic acid receptor responder (tazaro, none.none, 679 422293, X94453 Hs 114366, pyrraline 5-carboxylate synthetase (glut aldedh,aakιnase,TM=M,SS=N 677 431470, AA832417, Hs 139650 ESTs, none ig pkιnase,LRR,LRRCT, 676 418738, AW388633 Hs 6682, εolute carrier family 7, (cationic ammo, none.none, 675 418751, BE389014, Hs 372548 phospho ositide 3 kinase, regulatory su, SH2,none, 674
417886, AA214584, , ESTs, SPRY,7tm_3 ANF_receptor,none, 672 412926, AI879076, Hs 75061 , mxrophage myπstoyiated alanine rich C , MARCKS,, 670 437960, AI669586, Hs 369312 ESTs, none.none, 6 68
428953, AA306610, Hs 348183, tumor necrosis fxtor receptor superfami, 60s_πbosomal,Rιbosomal_L10,TNFR_c6,DEAD„ 6 66 444006, BE395085, Hs 334762, type I transmembrane protein Fn14, ldl_recept_a PKD,MHC_I,TM=M,SS=Y, 665
413040, AA193338, Hs 12321, sodium calcium exchanger, Na Ca_Ex,TM=Y,SS=M, 664 449656, AA002008, Hs 188633, ESTs, PIP5K,none, 6 64
447495, AW401864, Hs 18720, programmed cell death 8 (apoptosis indue, pyr_redox,TM=M,SS=N 662 446063, AI720140, Hs 151079, ESTs, ISK_Channel,none, 661 424762, AL119442, Hs 183684, eukaryotic translation initiation factor, none.none, 660
421554, AW137676, Hs 97775, ESTs, none.none, 6 59 418478, U38945, Hs 1174, cyclm-dependent kinase inhibitor 2A (me, ank,, 655 424905, NM 002497, Hs 153704, NIMA (never in mitosis gene a)-related k, pkmase,TM=M,SS=N 654 448730, AB032983, Hs 21894, KIAA1157 protein, PP2C,TM=M,SS=N, 654 433577, AW007080, Hs 284192 ESTs, none.none, 653
422627, BE336857, Hs 118787, transforming growth factor, beta induced, Fascιclm,ABCjran,ABC_membrane,GTP EFTU,TM=M,SS=M 653 442133, AW874138, Hs 129017, ESTs, type la transmembrane protein, LRR,LRRNT,LRRCT,TM=Y,SS=M, 652 430259, BE550182, Hs 375142, RalGEF-like protein 3, mouse homolog, fn3,RA RasGEF,TM=M,SS=M, 652 434263, N34895, Hs 79187, ESTs, ig.noπe, 649 418322, AA284166, Hs 84113, cyclm-dependent kinase inhibitor 3 (CDK, Y_phosphatase,DSPc,TM=M,SS=N, 648
419942, U25138, Hs 93841, potassium large conductance calcium acti, CaKB,TM=Y,SS=M, 647 421064, AI245432, Hs 101382, tumor necrosis fxtor, alpha-induced pro, noπe,TM=M,SS=N, 647 432636, AA340864, Hs 278562, claudin 7, PMP22 Claudιn,TM=Y,SS=M, 645
431685, AW296135, Hs 267659, vav 3 oncogene, CH,DAG_PE-bιnd,PH,RhoGEF,SH2,SH3,DC1,TM=M SS=N, 644 428832, AA578229, Hs 324239, ESTs, Moderately similar to ZN91_HUMAN Z, Osteopontin none, 6 39
436775, AA731111, Hs 372225, ESTs, none.none, 639
424343, AW956360, Hs 4748, adenylate cyclase xtivating polypeptide, 7tm_2,HRM,none, 6 37 421071, AI311238, Hs 104476 ESTs, Weakly similar to CGHU1E collagen , none,TM=Y,SS=M, 637 438209, AL120659, Hs 6111 , aryl-hydracarbon rxeptor nuclear transi, HLH,PAS,IL8,TM=M,SS=N, 637 438993, AA828995, , gb od77b08 s1 NCI_CGAP_Ov2 Homo εapienε , EGF,metaIthιo,ιntegπn_B,PSI,πone, 627
406400, , , kallikrein 8 (neuropsm/ovasin) (KLK8), trypsm,TM=M,SS=M, 627 429556, AW139399, Hs 314807, ESTs, none,TM=M,SS=N, 626
409269, AA576953, Hs 22972, steroid 5 alpha reductase 2-lιke, H5AR g, Steraιd_dh,TM=Y,SS=M 6 25 435732, AF229178, Hs 123136, leucine πch repeat and death domain con, none.none, 624 439668, AI091277, Hs 302634, fnzzled (Drosophila) homolog 8, Frιzzted,Fz,7tm_2,toxιπ_2,TM=Y,SS=M, 624
412276, BE262621, Hs 73798, mxrophage migration inhibitory fxtor (, MIF.sugar tr.none, 6 23 436961, AW375974, Hs 156704, ESTs, none.none, 623 434808, AF155108, Hs 256150, NY-REN41 antigen, none,TM=M,SS=N, 622
440006, AK000517, Hs 6844, NALP2 protein, PYRIN-Containiπg APAF1-lι, AM.NB-ARC.PAAD.DAPIN.NA.NA, 620 416224, NM.002902, Hs 79088, reticutocalbm 2, EF-haπd calcium bindin, efhaπd,, 620
449027, AJ271216, Hs 22880, dipeptidylpeptidase III, Peptιdase_M49,EGF,ιg,Neuregulιn,TM=M,SS=N, 6 19 418318, U47732, Hε 84072, transmembrane 4 superfamily member 3, traπsmembrane4,TM=Y,SS=M, 6 19 452551, L27071, Hs 29877, TXK tyroεine kinase, Bexh,WD40,SH2,SH3,pkmase,TM=M,SS=N, 6 14 418969, W33191, Hs 28907, hypothetical protein FLJ20258, SH3,TM=M,SS=N, 612 445462, AA378776, Hs 288649, hypothetical protein MGC3077, none,, 6 11
456534, X91195, Hs 100623, phospholipase C, beta 3, neighbor pseudo, LIM,PDZ,pkιnase„ 6 11 449700, L02867, Hs 78358, paraneoplastic antigen, noπe,TM=M,SS=N, 6 10
428479, Y00272, Hs 334562, cell division cycle 2, G1 to S and G2 to, pkιnase,ICE_p10,ICE_p20,TM=M,SS=M, 6 10 416209, AA236776, Hs 79078, MAD2 (mitotic arrest deficient, yeast, h, HORMA,TM=M,SS=N, 609 433159, AB035898, Hs 150587, kinesm like protein 2, bZIP.kinesm,, 608
432432, AA541323, Hs 115831, ESTs, ig.Sema.PSI.noπe, 607 409619, AK001015, Hs 55220, BCL2-assxιated athanogene 2, BAG,TM=M,SS=N, 604 412723, AA648459, Hs 335951, hypothetical protein AF301222, none,TM=M,SS=N, 603 424273, W40460, Hs 144442, phospholipase A2, group X, phoslιp,TM=M,SS=Y, 603 409430, R21945, Hs 346735, splicing fxtor, arginme/seπne-πch 5, DSPc.Rhodaπese.noπe, 600
421143, AB024536, Hs 102171, immunoglobulin superfamily containing Ie, ιg,LRR,LRRNT,LRRCT,TM=M,SS=M, 600 428677, AI657119, Hε 351582, troponm I, cardix, πone,TM=M,SS=N, 600 450098, W27249, Hε 8109, hypothetical protein FU21080, SET,zf-MYND,TM=M,SS=N, 600 410422, AL042014, Hs 63348, Homo sapiens, clone MGC 15203, mRNA, com, C1q,Collagen„ 5 99 419972, AL041465, Hs 182982, golgm 67, none.none, 599
421251, Z28913, Hs 102948, enigma (UM domain protein), LIM.PDZ,, 597 403362, , , NM.001615* Homo sapiens xlin, gamma 2, , xtιn„ 595 451541, BE279383, Hs 26557, plakophilin 3, Armadιllo_seg,TM=M,SS=N, 595 420253, AI656055, Hs 96200, neighbor of A kinase anchoπng protein 9, πone.NA.NA, 593 421506, BE302796, Hs 105097, thymidme kinase 1, soluble, TK,TM=M,SS=N, 593
450447, AF212223, Hs 25010, hypothetical protein P15-2, NTF2,TM=M,SS=N, 592 450747, AI064821, Hs 129953, ESTs Highly similar to 1818357A EWS gen, rrm.zf RanBP,GAS2, 592
415211, R64730 comp, Hs 155986, DEAD/H (Asp-Glu-Ala-Asp/His) box polypep, DEAD.helicase.C rrm.Ndr.Cys knot,TIL,vwa vwc,vwd,IQ,Rlla,abhydroIase TGF- beta,DUF139,TPR,DSPc,tsp_1,Rιbosomal_S21,rvp,TM=M,SS=N, 591 429910, NM.000867, Hs 2507, 5-hydroxytryptamιπe (serotonin) rxeptor, 7tm_1,TM=Y,SS=N, 5 90
447131, NM.004585, Hs 17466, retinoic acid receptor responder (tazaro, none,TM=Y,SS=N, 5 89 437952, D63209, Hs 5944, solute earner family 11 (proton-coupled, none,TM=Y,SS=M, 589 446291, BE397753 Hs 14623, interferon, gamma-mducible protein 30, GILT,TM=M,SS=Y, 589 453102, NM.007197, Hs 31664 frizzled (Drosophila) homolog 10, Fz,Fπzzled,7tm_2,TM=Y,SS=M 587 426761, AI015709, Hs 172089 PORIMIN Pro-oncosis receptor inducing me, noπe,TM=Y,SS=M, 585 425367, BE271188, Hs 155975, protein tyrosine phosphatase receptor t, none,TM=M SS=Y, 5 85 426108, AA622037, Hs 166468, programmed cell death 5, DUF122,TM=M,SS=N 584 5 450502, T08065, Hs 118262, ESTs lonjranε loπjrans, 584
442652 AI005163, Hs 201378 Homo sapiens cDNA FLJ40427 fis, none,TM=M,SS=N, 583 424917, AI636208 Hs 96901, hypothetical protein FU23049, none,TM=M,SS=N, 583
448569, BE382657, Hs 21486, signal transducer and activator of trans, SH2,STAT,STAT_bmd STAT_prat,TM=M,SS=N, 582 422616 BE300330, Hs 118725, selenophosphate εynthetase 2, AIRS,AIRS.C,TM=M,SS=N, 582 0 445133 AW157646, Hs 198689, ESTs, efhand,spectππ,GAS2 SH3,Plectιn,RA,Xylosejsom,FlιD,bZIP,Tropomyosm,Myc LZ,M,ldh_C,CH,AIP3,TM=M SS=N, 579
426215, AW963419, Hs 155223, stanniocalcm 2, Stanniocalcin,, 578 414482, S57498 Hs 76252, endothelin receptor type A, 7tm_1,TM=Y,SS=M, 575 414809, AI434699, Hs 77356, transferrin receptor (p90, CD71), PA,TM=Y,SS=N, 574 452683, AI089575, Hs 374574, progesterone membrane binding protein, homeobox.none, 572 5 432201 , AI538613, Hs 298241 , Transmembrane protease, seπne 3, Idl recepLa trypsm,TM=Y,SS=M 572
429345, Rl 1141, Hs 199695 hypothetical protein, K etra.SAM, 572 449458, AI805078, Hs 208261, ESTs, Fπzzled.Fz.none, 572
418526, BE019020, Hs 85838, solute earner family 16 (moπ∞arboxylic, none,TM=Y,SS=M, 571 418848, AI820961 , Hs 193465, ESTs, PDZ,pkιnase,none, 570 0 426227, U67058, Hs 154299 Human proteinase activated receptor-2 mR, 7tm 1,TM=Y,SS=M, 569
411190, AA306342, Hs 69171, protein kinase C-like 2, pkιnase,pkιnase_C,HR1,TM=M,SS=N 5 69 411263, BE297802, Hs 69360, kinesm like 6 (mitotic centromere ass∞, kιnesιn,TM=M,SS=N 5 69 445136, AI348014, Hs 143949, ESTs, Weakly similar to Achaete-Scute ho, lon.trans.ioπ.trans, 569 409223, AA312572, Hs 362852 phosphoιπosιtιde-3-kιπase, regulatory su, SH2,SH3,RhoGAP,none, 567 5 430016, NMJ04736, Hs 227656, xenotropic and polytrapic relrovirus rec, SPX,EXS,TM=Y,SS=N, 566
429638, AI916662, Hs 211577, kmxtin 1 (kinesm receptor), bZIP,Tropomyosm,spxtπn,LBP BPI_CETP,B56 M,TM=Y,SS=M, 565 450334, AF035959, Hs 24879 phosphatidic acid phosphataεe type 2C, PAP2,TM=Y,SS=M, 564 453950, AA156998, Hs 348037, eukaryotic translation initiation fxtor, none,, 564 425889, M57414, Hs 161305, txhykmin receptor 2, 7tm_1,TM=Y,SS=M, 564 0 432527, AW975028, Hs 102754, ESTs, none.none, 564
441384, AA447849, Hs 288660 retinoic xid induced 3, 7tm_3,noπe, 563 419080, AW150835, Hs 18878 hypothetical protein FLJ21620, 20G-Fell_Oxy,TM=M,SS=N, 563 447217, BE465754, Hs 17778, neuropilin 2, CUB,MAM,F5_F8_type_C,TM=M,SS=M, 561 440422, AW452696 Hs 130760, myosin phosphatase, target subunit 2, BTB,Kelch,ank,none, 558 5 431341, AA307211, Hs 251531, proteasome (prosome, macropain) subunit,, proteasome,TM=M,SS=N, 5 58 432805, X94630, Hs 3107, CD97 antigen, 7tm_2,EGF,GPS,FxCD,TM=Y,SS=M, 555 449230, BE613348, Hs 356392, melanoma cell adhesion molxule, ιg,ιεodh,Rιboεomal_L6,F-box TM=Y,SS=M, 5 55 441607, NM.005010, Hs 7912, neuronal cell adhesion molxule, WD40,fn3,ιg,TM=M,SS=N, 554 400303, AA242758, Hs 79136, UV-1 protein, estrogen regulated, none.none, 554 0 434826, AF155661 , Hs 22265, pyruvate dehydrogenase phosphatase, PP2C,noπe, 553
404210, , , NM 005936 Homo sapiens myeloid/lymphoid , FHA,PDZ,RA,DIL,TM=M,SS=N, 553 408051, AI623351, Hs 172148, ESTs, PH.RhoGAP.none, 553
436726, AA324975, Hs 198689, ESTs, Weakly similar to T00079 hypotheti, efhand,spectrιn,GAS2,SH3,Plxtιn,RA,Xylose ιsom,FlιD,bZIP,Trapomyosιn,Myc- LZ,M,ldh_C,CH,AIP3,TM=M,SS=N, 553 5 416084, L16991, Hs 79006, deoxythymidylate kinase (thymidylate km, none.none, 552
428667, AI375550, Hs 346868 nucleolar protein p40, homolog of yeast , none.none, 551 433907, AW296107, Hs 152686, ESTs, Armadιllo_seg,none, 550 442821, BE391929, Hs 8752, transmembrane protein 4, none,, 550 422282, AF019225, Hs 114309, apolipopratem L, MotA_ExbB,TM=Y,SS=M, 549 O 439820, AL360204, Hε 283853, Homo sapiens mRNA full length insert cDN, none.none, 549
428771, AB028992, Hs 193143, KIAA1069 protein, C2.PI PLC-Y,PI-PLC-X,TM=M,SS=N, 548 452256, AK000933, Hs 28661, Homo sapiens cDNA FU10071 fis, clone HE, GDI,7tm_1,none, 548 442013, AA506476, Hs 375009, Human DNA sequence from clone RP11-353C1 , none.none, 548 _ . 408056, AA312329, Hs 42331, ephπn A4, Ephnn,TM=M,SS=M, 547 5 422765, AW409701, Hs 1578, baculoviral IAP repeat-containing 5 (sur, BIR,TM=M,SS=N, 547
420297, AI628272, Hs 128757, ESTs, Weakly similar to ALULHUMAN ALU S, pkιnase,TUDOR,πoπe, 547 428385, AF112213, Hs 184062, putative RabS-interxting pratem, SH2.SH3,, 546
424517, AI539443, Hs 137447, Homo sapienε cDNA FU12169 fis, clone MA, SH2,STAT,STAT_bιnd,STAT_prat,noπe, 545 441560, F13386, Hε 7888, v-erb-a avian erythroblastic leukemia vi, pkιnase,Rxep_L_domaιn,Fuπn ke.YLP.none, 544 0 414883, AA926960, Hs 348669, CDC28 protein kinase 1, CKS„ 543
450402, BE218027, Hs 89969 ESTs, SH3,noπe, 542 428484, AF104032, Hs 184601, solute earner family 7 (cationic ammo , aa_permease8,pyπdoxal_deC,bromodomaιn,PHD,MBD,AT_hook,DDT,PI3_PI4 kιnase,FAT,FATC,BolA,RUN,TM=M,SS=N, 542 430696, AA531276, Hs 59509, ESTs, pkιnase,PP2C,noπe, 542 65 412350, AI659306, Hs 73826, protein tyrosine phosphatase, non rxept, Y_phosphatase,Band_41,PDZ,TM=M,SS=N, 542
444783, AK001468, Hs 62180, anillin (Drosophila Scraps homolog), act, PH.none, 541 448379, AI097463, Hs 21035, KIAA1130 protein, noπe.Zip, 541 410082, AA081594, Hs 158311, Musashi (Drosophila) homolog 1, rrm,TM=M,SS=N, 541 411817, BE302900, Hs 72241, mitogen-xtivated protein kinase kinase , pkιnase,TM=M,SS=M, 540 70 445413, AA151342, Hε 12677, CGI-147 protein, UPF0099,TM=M,SS=M, 539
451863, AL120634, Hs 331803, ATPase, Ca transporting, plasma membrane, cpn60_TCP1,E1-E2_ATPase,Catιon_ATPase_C,Catιon_ATPase_N,Hydrolase„ 538 442875, BE623003, Hs 23625, Homo sapienε clone TCCCTA00142 mRNA sequ, K etra DUF51,none, 538 439963, AW247528, Hε 6793, platelet-activating factor xetylhydrola, PAF-AH_lb,Lιpase_GDSL,TM=M,SS=N, 536 450825, AC005954, Hs 25527, tght junction protein 3 (zona xcludens, PDZ.Guanylale.kin,, 534 75 441031, AH 10684, Hs 7645, fibππogen, B beta polypeptide, fibπnogen_C,G-alpha,arf,TM=M,SS=M, 5 33
408369, R38438, Hs 118747, SLC15A2 Solute camerfamily 15 (H+/pep, PTR2,TM=Y,SS=N, 533 435391, AA704588, Hs 58934, ESTs, PIP5K,none, 533 411779, AA292811 , Hs 72050, non metastatic cells 5, protein expresse, NDK„ 533 422170, AI791949, Hs 112432, and Mulleπan hormone, TGF-beta„ 532 8 O 447350, AI375572, Hs 172634, v-erb a avian erythroblastic leukemia vi, pkιnase,Rxep_L_domaιn,Fuπn lιke,YLP,none, 532
449964, AW001741, Hs 24243, hypothetical protein FU10706, pkιnase,TM=M,SS=N, 531 426427, M86699, Hs 169840, TTK protein kinase, pkinase,, 530 430407, H23551, Hs 30974, ESTs, pkmase.PBD.noπe, 529
Figure imgf000275_0001
438564, AA381553, Hs 198253, major histocompatibility complex, class , ig.MHC.II.alpha none, 489
427640, AF058293, Hs 180015 D-dopachrome tautomerase, COX8 SHMT,MIF,GST_C,EF1G_domaιn,GST_N,S1,Fz,Fπzzled,calretιculιπ,7tm_2,rrm,PAP_assx,TM=Y,SS=M 488 434521 , NM.002267, Hs 3886 karyopheπn alpha 3 (importin alpha 4), Armadιllo_seg,IBB,TM=M SS=N, 488 414821, M63835 Hs 77424, Fc fragment of IgG, high affinity la re, ιg,TM=Y,SS=M, 4 88 424118, BE269041, Hs 140452, cargo selection protein (mannose 6 phosp peπlipiπ,, 488
410639, BE269047, Hs 65234, hypothetical protein FLJ20596 DEAD.helicase_C.PRK AIP3 TM=M SS=N, 487 417089, H52280, Hs 18612, Homo sapienε cDNA FLJ21909 fis, clone H, voltage_CLC,CBS,none, 486 429303 AW137635, Hs 44238, ESTs, Weakly similar to S65657 alpha 1 C-, Phosphodιest,Somatomedιn B.Eπdonuclease.none, 486 417666, AI345001 , Hs 82380, menage a trois 1 (CAK assembly fxtor), zf C3HC4,TM=M,SS=N, 486 453864, AW021407, Hs 21068 hypothetical protein, none.none, 486
453082, H18835, Hs 31608, hypothetical protein FU20041, ιon_trans,TM=Y,SS=M, 485 413407, AI356293, Hs 75339, mositol polyphosphate phosphatase-like , SH2,SAM,Exo_endo_phos„ 485 417866, AW067903, Hs 82772, collagen, type XI, alpha 1, Collagen,COLFI,TSPN,lammιn_G CorA,, 485 435652, N32388, Hs 334370, uπcharacteπzed hypothalamus protein HBE, none,TM=M,SS=N, 484 419355, AA428520, Hs 90061 , progesterone binding protein, heme 1 ,TM=Y,SS=M, 483
431441, U81961, Hs 2794, sodium channel, nonvoltage-gated 1 alpha, ASC,TM=Y,SS=N, 483
408983, NM.000492, Hs 663, cystic fibrosis transmembrane conductanc, ABC_traπ,ABC_membrane,PRK,Bx_export_3,TM=Y,SS=N, 483 425465, L18964, Hs 1904, protein kinase C, iota, pkιnase,DAG_PE-bιnd,pkιπase_C,OPR,TM=M,SS=N, 482 435232, NM.001262 Hs 4854, cyclm-dependent kinase inhibitor 2C (p1, ank,TM=M,SS=N, 481 424490, AJ278016, Hs 55565, ankyrm repeat domain 3, ank pkιnase,TM=M,SS=N, 481
425743, BE396495, Hs 159428, BCL2 associated X protein, Bel 2,TM=Y,SS=N, 481 453354, W55946, Hs 234863, Homo sapiens cDNA FLJ12082 fis, clone HE, traπsmembraπe4,none, 481 450883, NM.001348, Hs 25619, death-associated protein kmase 3, pkιnase,TM=M,SS=N, 479 429736, AF125304, Hs 212680, tumor necrosis factor receptor superfami, TNFR_c6,TM=M,SS=M, 479 431183, NM.006855 Hs 250696, KDEL (Lys-Asp-Glu-Leu) endoplasmic retic, ER_lumeπ_rxept,TM=M,SS=M, 479
409960, BE261944, Hs 355264, hexokinase 1 , none.none, 478
422795, AB033109, Hs 375610, KIAA1283 protein, 7tm_1,kazal,A2M,A2M_N,TM=Y,SS=M, 478 423619, T48691, Hs 249159, adrenergic, alpha-2A-, rxeptor, 7tm_1,7tm_2,TM=Y,SS=M, 478 429305, AF095727, Hs 287832, myelin protein zero-like 1, ιg,traπsmembrane4,TM=Y,SS=M, 478 427700, AA262294, Hs 180383, dual spxificity phosphatase 6, Rhodaπese DSPc,TM=M,SS=N, 477
447343, AA256641, Hs 236894, ESTs, Highly similar to S02392 alpha-2-m none.none, 476
444672, Z95636, Hs 11669, laminin, alpha 5, lamiπin.EGF.Iammin G,EGF,TNFR_c6,lamιnιπ_B lammιn_Nterm,metalthιo,Trapomyosιn,DUF164,p450,TM=M,SS=N, 476 407722, BE252241, Hs 38041, pyπdoxal (pyndoxine, vitamin B6) kinas, pfkB,TM=M,SS=N, 475 438330, AW450572, Hs 257316, ESTs, pkmase.zf C4,ERM,CNH,none, 475 410687, U24389 Hs 65436, lysyl oxidase like 1, Lysyl_oxιdase„ 475
411165, NM.000169, Hs 69089, galactosidase, alpha, Melibiase,, 475 425548, AA890023, Hs 1906, prolactiπ receptor, fn3,TM=Y,SS=M, 473 434158, T86534, Hs 14372, ESTs, adenylatekinase.none, 473 459035, AW291109, Hs 332563, ESTs, Weakly similar to T31611 hypotheti, none,SH3,myosιn_head,IQ, 473 409012, AL117435, Hs 49725, DKFZP434I216 protein, PH,RhoGEF,TM=M,SS=M, 473
434503, T96231, Hs 17762, ESTs, SH3,Sorb,none, 473
446342, BE298665, Hs 14846, solute carrier family 7 (cationic ammo , πoπe,TM=M,SS=N, 472 427418, AA402587, Hs 356667, LAT1-3TM protein, none.none, 471
449433, AI672096, Hs 9012, ESTs, Weakly similar to S26650 DNA-biπdi, Fπzzled,Fz,Fπzzled,Fz, 471 418910, Z25821 , Hε 89466, Homo sapiens, Similar to dodecenoyl-Coen, ECH„ 470
414907, X90725, Hs 77597, polo (Drasophia) like kinase, Rιbosomal_L37x,pkιnase,POLO box,tRNA-synL1b,dynamιn,dynamιn_2,GED,bZIP,M„ 470 442199, BE277633, Hε 372542, etoposide-induced mRNA, πone,TM=Y,SS=M, 469 418870, AF147204, Hs 89414, chemokine (C-X-C motif), receptor4 (fus, 7tm_1,7tm_2,TM=Y,SS=M, 469 453922, AF053306, Hε 36708, budding uninhibited by benzimidazoleε 1 , none,, 469 418558, AW082266, Hs 86131, Fas (TNFRSF6)-ass∞ιated via death domai, death.DED,, 468
434164, AW207019, Hε 148135, εeπne/thrxnine kmase 33, pkιnase,TM=M,SS=N, 468 443323, BE560621, Hs 9222, eεtrogen rxeptor binding site assxiate, none,TM=M,SS=M, 468 400288, X06256, Hs 149609, integnn, alpha 5 (fibroπ∞tin rxeptor,, ιntegπn_A,FG-GAP,TM=Y,SS=N, 468 418838, AW385224, Hs 35198, ectonucleotide pyrophosphatase/phosphodi, Phosphodιest,TM=Y,SS=M, 467 417426, NM 002291 , Hs 82124, laminin, beta 1 , lamιnιn_EGF,lamιnιn_Nterm,ιntegπn_B„ 467
425976, C75094, Hs 334514, NG22 protein, voltage_CLC,TM=Y,SS=M, 466 407844, AW073716, Hs 8037, ESTs, transmembrane4,none, 466 450656, AA010539, Hs 18912, unnamed protein product, zf-C2H2„ 466 420311, AW445044, Hε 38207, Human DNA εequence from clone RP4-530I15, none.none, 465 404287, , , FGENESH predicted novel CUB-domain conta, none.none, 464
452747, BE153855, Hs 61460, Ig superfamily receptor LNIR, ιg,Rhabd_gIycop,TM=Y,SS=M, 463 426680, AA320160, Hs 171811, adenylate kinase 2, adenylatekιnase,TM=M,SS=N, 463 430397, AI924533, Hs 105607, bicarbonate transporter related protein , HC03_cotransp,TM=Y,SS=N, 463 447656, NM.003726, Hs 19126, src kmaεe-assxiated phosphoprotein of , SH3,PH,TM=M,SS=N, 463 414271, AK000275, Hs 75871, protein kmase C binding protein 1, bromodomaιn,PHD,PWWP,zf-MYND,TM=M,SS=N, 462
429126, AW172356, Hs 99083, ESTs, 7tm_1 ,none, 461 429150, AF120103, Hs 197366, smoothened (Drosophila) homolog, COX8,SHMT,MIF,GST C,EF1G_domaιn,GST N,S1,Fz,Fnzzled,calretιcuIιn,7tm 2,rrm,PAP assoc,TM=Y,SS=M,
460 409220, BE243323, Hs 51233, tumor necrosis fxtor receptor superfami, TNFR.c6,death,Lipoprotein_5,TIL,TM=Y,SS=M, 460 421921, H83363, Hs 355993, translxase of inner mitochondnal membr, zf-Tιm10_DDP,efhaπd,CH,spxtππ,εerpιn,TM=M,SS=N, 460
429083, Y093S7, Hε 227817, BCL2-related protein A1, Bd-2,TM=M,SS=N, 459 400290, H18836, Hs 31608, hypothetical protein FLJ20041, noπe.Cys.kπot, 459 430379, AF134149, Hs 240395, potassium channel, subfamily K, member 6, ιoπ_trans,TM=Y,SS=M, 459 409645, AI142265, Hs 55498, geranylgeranyl diphoεphate synthase 1, polyprenyl_synt,TM=M,SS=N, 459 427373, AB007972, Hs 130760, myosin phosphatase, target subunit 2, ank,TM=M,SS=N, 458
437212, AI765021, Hs 210775, ESTs, UDPGT.noπe, 458
430396, D49742, Hs 241363, hyaluronan-binding protein 2, ank,death,ZU5,EGF,kπngle,trypsιπ,Nebulm L1M„ 457 452069, AB028949, Hs 183994, KIAA1026 protein, Metallophos,TM=M,SS=N, 456 416041, AA345547, Hs 53263, hypothetical protein FU13287, WD40„ 455 434511, R28982, Hs 18106, ESTs, pkmase.Glyco hydro_39, 455
410174, AA306007, Hs 59461, DKFZP434C245 protein, none.DSPc, 455
418758, AW959311, Hs 172012, hypothetical protein DKFZp434J037, pkιπase,RI01,TM=M,SS=N, 455
451367, AA923729, Hs 26322, cell cycle related kinase, pkmase,TM=M,SS=N, 454 417433, BE270266 Hs 82128, 5T4 oncofetal trophoblast glycoprotein, LRR LRRNT,LRRCT,TM=Y,SS=M, 454 411296, BE207307, Hs 10114, growth suppressor 1, 20G-Fell_Oxy,TM=M SS=M, 453 439975, AW328081, Hs 6817, inosine tπphosphatase (nuclxside tπph, Hamlp lιke,TM=M,SS=N, 4 53 431992, NM_002742 Hε 2891 protein kinase C, mu pkιnase,DAG_PE-bιnd,PH,TM=M,SS=M, 453 443303, U67319 Hs 9216 caspase 7, apoptosis-related cysteine pr, pkinase ICE_p10,ICE_p20,TM=M,SS=M, 453
428005, AW302245 Hs 181390, casein kinase 1, gamma 2, pkmase,TM=M SS=N, 452 407775, NM.004914, Hs 38772, RAB36, member RAS oncogene family, ras arf,TM=M,SS=N, 452 435523 T62849, Hs 11090, membrane spanning 4-domaιns, subfamily A, none,TM=Y,SS=M, 451 447321, AW271217 Hs 281434, Homo sapiens cDNA FLJ14028 fis, clone HE, none.none, 451 405484, , , C3002124- gι|12737280|ref)XP_0066822| k, none,, 450
443605, H06865, Hs 134131, ESTs, efhand.ion.tranε.none, 450
431738, AW237726, Hs 288549, hypothetical protein FLJ14710, 7tm_1,zf-C3HC4,fn3,SPRY,KRAB zf-C2H2,rve,zf-B_box,TM=Y,SS=M, 450 422112, BE540240, Hs 111783, Lsm1 protein, Sm.BAG,, 449
418869, AW516565, , gb xq01d05 x1 Soares_NHCeC_cervιcal_tumo, πone,RasGAP,WW,IQ, 448 447898, AW969638, Hs 112318, 62 kd protein, none.none, 448
450607, AL050373, Hs 25213, hypothetical protein, SH3,TM=M,SS=N, 448 418918, X07871, Hs 89476, CD2 antigen (p50), sheep red blood cell , ιg,TM=Y,SS=M, 448 424823, NM 006226 Hs 153322, phospholipase C, epsilon, C2,PH,PI-PLC-Y,PI-PLC-X,TM=M,SS=N, 448 426812, AF105365 Hs 172613, solute carrier family 12 (potassium/chlo, none,TM=Y,SS=N, 447 439237, AW408158 Hs 318893, ESTs, Weakly similar to A47582 B-cell gr, Furιn-lιke,pkιnase,Recep_L_domaιπ,YLP,none, 447
435615, Y15065 Hs 4975, potassium voltage gated channel, KQT-lik, lon.traπs KCNQ1_channel,TM=Y,SS=N, 447 427557, NM.002659, Hs 179657, plasminogen activator, urokinase rxepto UPAR_LY6,ET,PLA2_ιnh„ 447 428727, AF078847, Hs 78452, general transcnption factor HH, polype, PH04,LIM,TM=M,SS=N, 446 412760, AW379030 Hs 41324, ESTs, Cbl.N,Cbl_N2,Cbl_N3,UBA,zf-C3HC4,none, 446 409093, BE243834 Hs 50441 , CGI-04 protein, Rιbosomal_L37ae,pkmase,POLO_box,tRNA synt_1 b,dynamιπ,dynamιn_2,GED,bZIP,M„ 446
434375, BE277910 Hs 3833, 3-phosphoadenosine 5'-phosphosulfate sy, APS_kιnase,ATP-sulfurylase,PRK,Thymιdylate_km„ 446 447434, R16890, Hs 137135, ESTs, pkιnase,fn3,ιg,pkmase,fn3, 445
422010, AA302049, Hs 31181 , Homo sapiens cDNA FLJ23230 fis, clone C, none,SDF,sugar_tr, 445 414108, AI267592, Hs 75761, SFRS protein kinase 1, ank PH,Oxystera)_BP,pkinase,TM=M,SS=N, 444 457001, J03258, Hs 2062, vitamin D (1,25- dihydraxyvitamin D3) re, hormoπe_rx,zf-C4,Metallothιo_5,TM=M,SS=N, 444
409686, AK000002 Hs 55879, Homo sapiens mRNA, cDNA DKFZp434L0827 (f, ABC ran.ABC membrane TM=M SS=M, 444 408113, T82427, Hs 194101 , Homo εapiens cDNA FU20869 fis, clone A, 7tm_3,noπe, 444 436823, AW749865, Hs 117077, ESTs, Weakly similar to I38022 hypotheti aa_permeases,zf-
C2H2.KRAB pyπdoxal deC,bromodomaιn,PHD,M8D,AT_hook,DDT,PI3_PI4_kιπase,FAT FATC,BolA,RUN,TFIIS,TM=M,SS=N, 444 450505, NM.004572, Hs 25051 , plakophilin 2, Armadιllo_seg,TM=M,SS=N, 443
437915, AI637993, Hs 202312, Homo sapiens clone N11 NTera2D1 teratoca, none.none, 443 417412, X16896, Hs 82112, interleukin 1 rxeptor, type I, ιg,TIR,TM=M,SS=M, 443 445033, AV652402, Hε 72901 , cyclm-dependent kinase inhibitor 2B (p1 , ank , 443 411027, AF072099, Hs 67846, leuk∞yte immunoglobulin-like rxeptor, , ιπosιtol_P,ιg,TM=M,SS=N, 443 452124, AA454220 Hs 61170, ESTs, pkmase.none, 443
422599, BE387202, Hs 118638, noπ-metastatic cells 1 , protein (NM23A) , NDK,PH,Oxysterol_BP„ 442 416202, AW964492 Hs 169624, ESTs, none,TM=M,SS=N, 442 441518, AW161697, Hs 294150, ESTs, Y_phosphatase,DSPc,none, 442
441680, AW444598 Hs 7940, RAP1, GTP-GDP dissociation stimulator 1, Armadιllo_seg,TM=M,SS=N, 442 431429, AF072813, Hs 252831, reticulon 3, Relιculon,Fz,ιg kπngle,pkιnase,TM=Y,SS=N, 442
453870, AW385001, Hs 8042, Homo sapienε cDNA FLJ23173 fis, clone L, FG-GAP,ιntegπn_A,NIF, 441 421242, AW161386, Hs 13561, hypothetical protein MGC4692, none,NA,NA, 441 456362, AW973003, Hs 179909, hypothetical protein FU22995, none,TM=M,SS=N, 441 419073, AW372170 Hs 183918, Homo sapiens cDNA FLJ12797 fis, clone NT, death,ZU5„ 441 432211, BE274530, Hs 273333, hypothetical protein FLJ10986, FGGY_C,TM=M,SS=N, 441
413367, NM.006517, Hs 75317, solute earner family 16 (monxarboxylic, sugar_tr;TM=Y,SS=N, 441 458097, AW341135, Hs 58104, ESTs, none,SH3,PID, 440
458248, BE407379, Hs 108082, ESTε, Weakly similar to T31636 hypotheti, C1q,Collagen,TM=M,SS=Y, 440
427681, AB018263, Hs 284232, tumor nxrosis fxtor rxeptor superfami, death,TNFR_c6,PH,Xlιnk,RhoGEF,Metallothιo_5,TM=M,SS=M, 440 443693, AI344782, Hs 9683, DnaJ (Hsp40) homolog, subfamily C, membe, rrm,DnaJ,TPR,TM=M,SS=N, 440
437162, AW005505, Hs 5464, thyroid hormone rxeptor coxtivating pr, bromodomaιn,TM=M,SS=N, 439 453891, AB037751 , Hs 301242, Homo εapieπs mRNA full length insert cDN, none.none, 439 442572, AI001922, Hs 135121, hypothetical protein FLJ22415, none,HSP70, 439 427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lllb, r, ιg,TM=Y,SS=M, 437 445817, NM.003642, Hε 13340, histone xetyltransferase 1, none,TM=M,SS=N, 437
444895, AI674383, Hs 22891 , solute earner family 7 (cationic ammo , ASC,death,TNFR_c6, 437 408912, AB011084, Hs 48924, KIAA0512 gene product, ALEX2, Armadιllo_seg,TM=M,SS=M, 437 432106, N58323, Hs 269098, ESTs, Weakly similar to RETROVIRUS-RELAT, SH3,PDZ,Guanylate_kιn,none, 437 418283, S79895, Hs 83942, cathepsin K (pycnodysoεtoεis), Peptidase.CT „ 437 445826, BE313754, Hs 13350, Homo εapienε mRNA, cDNA DKFZp586D0918 (f, ιg,tεp_1,ZU5,Nucl∞sιde_tran, 437
417874, BE616160, Hs 82829, protein tyrosine phoεphatase, non-rxept, Y phosphatase,TM=Y,SS=N, 436 400257, , Hs 76366, ENSP00000000452 BAD protein (BCL-2 biπdi, none,TM=M,SS=N, 436 431476, BE612705, Hs 256697, histidine triad nuolxtide-binding prote, HIT,, 436 416178, AI808527, Hs 192822, serologically defined breast cancer anti, noπe,TM=M,SS=N, 436 456629, AW891965, Hs 367942, histone dexetylase 3, HSP90,HATPase c,zf-C2H2,PHD,none, 436
- 427716, L38951, Hs 180446, karyopheππ (importm) beta 1, Armadιllo_seg,HEAT,TM=M,SS=N, 435 425843, BE313280, Hs 159627, death assxiated protein 3, myb_DNA-bmdιπg,PAH,BAH,bromodomaιn,PHD,SET,TM=M,SS=N, 435 420261 , AW206093 Hs 748, fibroblast growth fxtor receptor 1 (fms, pkmase,ιg,pkmase,ιg,p450,SET,PWWP, 435 445926, AF054284, Hs 334826, splicing fxtor 3b, subunit 1, 155kD, none,TM=M,SS=N, 435 410726, AI623859, Hs 15936, ESTs, pkιnase,pro_ιsomerase,none, 435
433996, AW135357, Hs 192374, ESTs, HSP90,HATPase_c,UDG, 434 433592, NM.004642, Hs 3436, deleted in oral cancer (mouse, homolog) , none,TM=M,SS=N, 434 437103, AW139408, Hs 152940, ESTs, Choline.kinase.none, 434 410068, AI633888, Hs 58435, FYN-biπding protein (FYB-120/130), SH3,TM=M,SS=N, 434 427349, AA360154 Hs 177415, Fmkel Biskis-Reilly murine sarcoma viru, ubιquιtιn,TM=M,SS=N, 433
439807, AA376417, Hs 374608, hypothetical protein MGC 5244,, abhydrolase_2,TM=M,SS=M, 433 453308 AW959731, Hs 323098, ESTs, none,pkιnase,Actιvιn_rxp, 433 424893, AW295112, Hs 153648, Homo sapiens cDNA FLJ13303 fis, clone OV, SAM,, 433 444664, N26362, Hs 11615, map kinase phosphatase-like protein MK-S, DSPc TM=M,SS=N, 433 429655, U48959 Hs 211582, myosin, light polypeptide kinase, pkinase fn3,ιg,noπe, 432 409121, AA902256, Hs 78979, Golgi apparatus protein 1, cys.πch.FGFR none 432 430280, AA361258, Hs 237868, interleukin 7 receptor, frι3,none, 432 423798, AF047033 Hs 132904, solute carrier family 4, sodium bicarbon, HC03_cotransp TM=Y,SS=M, 429
425654, AB033022, Hs 158654, KIAA1196 protein, zf C2H2,TM=M,SS=N, 429 457500 NM.002759, Hs 274382, protein kinase, interferon-inducible dou, dsrm,pkιnase,TM=M SS=N, 429 427127, AW802282, Hs 22265, pyruvate dehydrogenase phosphatase, PP2C,none, 429 447191, NM.014521, Hs 17667, SH3-domaιn binding protein 4, SH3,TM=M,SS=N, 429 408331 , NMJ07240, Hs 44229, dual specificity phosphatase 12 DSPc,TM=M,SS=N, 429
441130, AI160734, Hs 267604, Homo sapiens PNAS-129 mRNA, complete eds, BTB.Kelch.K etra DSPc,TM=M,SS=N, 428 430057, AW450303, Hs 2534, bone morphogenetic protein rxeptor, typ, Activin.rxp.pkinase TM=Y,SS=M, 428 430250, NM.016929 Hs 283021 , chloπde intracellular channel 5, none,TM=M,SS=N, 428 406774, AW518383, Hs 177592, πbosomal protein, large, P1, 60s_πbosomal , 428 413809, L25851, Hs 851, integπn, alpha E (antigen CD103, human , vwa ιntegπn_A,FG-GAP,TM=M,SS=Y, 427
443960, AI093577, Hs 255416, hypothetical protein FU21986, TTL,TM=M,SS=N, 427 427378, BE515037, Hs 177556, melanoma antigen, family D, 1, MAGE,TM=M,SS=N, 427 412204, AI125507, Hs 24937, ESTs, ιg,rrm,none, 426 439506, AI361238 Hs 41136, ESTs, MAM,pkmase,Nucleoplasmιn,none, 426 451295, AI557212 Hs 17132, ESTs, Moderately similar to I54374gene , pkinase DAG_PE-bιnd,pkιπase_C,OPR none, 426
452488, N74921, Hs 184389, ESTs, none,TM=M,SS=N 426
460973, AF012072, Hs 25732, eukaryotic translation initiation fxtor, W2.MA3 MIF4G,TM=M,SS=N, 426 452437, AA026237, Hs 181272, ESTs, eflιand,ιon_trans,none, 426 438204, AI589645, Hs 128690, ESTs, noπe,7tm 1 , 425 424756, AW504657, Hs 152931, lamm B rxeptor, ERG4_ERG24,FKBP,TM=Y,SS=N, 425
430570, AI417881, Hs 292464, ESTs, 7tm_2,Fz,Fπzzled,none, 425 445709, H02592, Hs 74280, ESTs, PDZ,noπe, 425 428134, AA421773, Hs 161008, ESTs, Armadιllo_seg none, 424 434149, Z43829, Hs 244624, hypothetical protein MGC5469, none,TM=M,SS=M, 424 425118, AU076611 Hs 154672, methylene tetrahydrofolate dehydrogenase, yb.DNA- binding THF_DHG_CYH,THF_DHG_CYH_C,CAP_GLY,AAA LON,Peptιdase_C9,bZIP,M xan_ur_permease,HC03_cotransp,TM=M,SS=N, 424 433376, AI249361, Hs 74122, caspase 4, apoptosis related cysteine pr, CARD,ICE_p10,ICE_p20„ 424 447818, W79940 Hs 355279, Homo sapiens clone 24670 mRNA sequence, noπe.pkmase, 424 460684, AA872605, Hs 25333, interleukin 1 rxeptor, type II, ιg,TM=Y,SS=M, 423 435542, AA687376 Hs 351226, ESTs, SH3,ιg,pkιnase,PH,spxtπn,RhoGEF,none, 423
426224, BE085860, Hs 374468, karyopheπn (importm) beta 2, Armadιllo_seg,HEAT,TM=M,SS=N, 423 413284, AU077055, Hs 289107, bxuloviral IAP repeat-containing 2, zf-C3HC4,CARD,BIR,death,ιg TM=M,SS=N, 422 421917, AB028943, Hs 109445, KIAA1020 protein, BTB.zf C2H2,PI3_PI4_kιnase,PI3Ka,TM=M SS=N, 422 _ 431239, AL039971 , Hs 251216, hypothetical protein DKFZp434A196, SH2,ank,WH2„ 422 0 419685, W76083, Hs 134185, ESTε, noπe,TM=M,SS=N, 422
431630, NM_002204, Hs 265829, integnn, alpha 3 (antigen CD49C, alpha , FG-GAP,Rhabd_glycop,ιntegππ_A,TM=Y,SS=M, 422 425177, AF127577, Hs 155017, nuclear rxeptor interacting protein 1, none,, 421 422219, AW978073 Hs 1010, regulator of mitotic spindle assembly 1, pkinase none, 421 450746, D82673, Hs 278589, general transcnption factor II, i, none,SH3,PX, 421 5 428023, AL038843, Hs 374530, Homo sapienε cDNA FU23602 fis, clone L, aa_permeases,pyπdoxal_deC,bromodomaιn,PHD,MBD,AT hook,DDT,PI3_PI4_kιnase,FAT,FATC,BolA,RUN,TM=M,SS=N, 421 416907, W60909, , gb zd29g10 s1 Soares_fetal_heart_NbHH19W, loπ.trans.none, 421 411768, NM.013371, Hs 71979, interleukin 19, IL10„ 421 425262, D87119, Hs 155418, GS3955 protein, pkinase,, 421 O 430035, NM.003463, Hs 227777, protein tyrosine phosphatase type IVA, m, Y phosphatase,DSPc,TM=M,SS=N, 421
411789, AF245505, Hs 72157, Adlican, ιg,LRR,LRRNT,LRRCT,TM=M,SS=M, 415 416636, N32536, Hs 42645, solute earner family 16 (monxarboxylic, none.none, 414 419452, U33635, Hs 90572, PTK7 protein tyrosine kinase 7, ιg,pkιnase,TM=Y,SS=M, 4 13 431745, AW972448, Hs 163425, Novel FGENESH predicted cadhenn repeat , none.none, 410 5 416965, N26223, Hs 160436, MDAC1, none.NA.NA, 394
426890, AA393167, Hs 41294, ESTε, none.none, 388
442438, AA995998, Hε 370007, gb os26b03 s1 NCI.CGAP.Kid5 Homo εapiens, none,DNA_pol_B,DNA_pol_B_exo, 386 412314, AA825247, Hs 356084, downstream of G protein-coupled rxepto, 7tm_1,TM=Y,SS=M, 384 448243, AW369771, Hs 367688, integπn, beta 8, integπn B.πoπe, 364 0 439318, AW837046 Hs 6527, G protein-coupled rxeptor 56, 7tm 2,CytC asm,GPS,TM=Y,SS=M, 361
415999, AA172179, Hs 294029, ESTs, none.none, 360 429466, M85835, Hs 12827, ESTs, none.none, 345
407853, AA336797, Hs 40499, diekkopf (Xenopus laevis) homolog 1 , none,TM=M,SS=Y, 334 400517, , , lengsm, none,TM=M,SS=N, 317 5 439180, AI393742, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Furm lιke,pkmase,Rxep_L_domam,Fuπn-lιke,pkιnase,Rxep_L_domaιn,Peptιdase_M24, 288
426158, NM_001982, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Fuππ-lιke,pkιnase,Rxep_L_domam,Fuππ lιke,pkιnase,Rκep_L_domaιn,Peptιdase_M24, 284 414521, D28124, Hs 76307, neurablastoma, suppression of tumoπgeni, DAN,TM=M,SS=M, 281 424522, AL134847, Hs 149957, πbosomal protein S6 kinase, 90kD, polyp, pk ase.pkinase C„ 270 438167, R28363, Hs 24286, chemokine binding protein 2 (CCBP2), mRN, none,TM=Y,SS=M, 268 0 418888, AU076801, Hs 89436, cadhenn 17, LI cadhenn (liver-intestm, cadheπn,TM=Y,SS=M, 217
TABLE 23B
Pkey Unique Eos probeset identifier number 5 CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT Number Accesεion
409745 MH1944 5 BI030997 AA921874 AW188822 BI027862 A1347618 AI361453 AI088754 AW207491 AA077391 BG012775 BG997382AA286833 AA150722 BI007625 O BI027864 BI009100 BI006275 BI006270 BI031000 BI029864 BI006277 BI007627 BI006266 BI006991 BI006990 BI007763 BI007762 BG997377 AA150780 BI033518
BI027818 BG015789 BI033807 AA341445 417886 1031334.1 AA210987 D57294AA214584AA207006 D56572
438993 2580163.1 AI926361 AA834879 AA828995 418869 12789.14 AA229762AA230035 416907 1112245.1 W60909 W61051 M78905 BG959483
TABLE 23C
Pkey Unique number corresponding to an Eos probeεet
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
406400 9256298 Plus 1553-1712,1878-2140,42524385,59226077
403362 8571772 Plus 64099-64260
404210 5006246 Plus 169926-170121
404287 2326514 Plus 53134-53281
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
400517 9796686 Minus 49996-50346
TABLE 24A 571 GENES UP-REGULATED IN HEAD AND NECK TUMORS COMPARED WITH NORMAL BODY TISSUES
Table 24A lists about 571 genes up-regulated in head and nxk tumors compared with normal body tissues These genes were selxted from 59680 probesetε on the Eos/Affymetπx Hu03 Genechip array Gene expression data for exh probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative level of mRNA expression
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
Rl 70th percentile of Al for head and neck cancer samples vs the 80th percentile of the Al for normal body tissues
Pkey ExAccn UnigenelD Unigene Title R1
421155 H87879 Hs 102267 lysyl oxidase 16600
452401 NM 007115 Hs 29352 tumor nxrosiε fxtor, alpha-induced pro 15600
434377 AW137148 Hs 306593 Homo εapiens cDNA FLJ11382 fis, clone HE 8000
438274 AI918906 Hs 55080 ESTs 2800
401486 121 00
446999 AA151520 Hs 334822 hypothetical protein MGC4485 12600
423887 AL080207 Hs 134585 DKFZP434G232 protein 1300
419569 AI971651 Hs 91143 jagged 1 (Alagille εyπdrome) 9800
428505 AL035461 Hs 2281 chromogranin B (sxretogranin 1) 1 00
420602 AF060877 Hs 99236 regulator of G-protein signalling 20 3500
445019 AI205540 Hs 281295 ESTs 9300
452281 T93500 Hs 28792 Homo sapiens cDNA FU11041 fis, clone PL 27062
449722 BE280074 Hs 23960 cyclin B1 981
423575 C18863 Hs 163443 Homo sapiens cDNA FU11576 fis, clone HE 373 00
424086 AI351010 Hs 102267 lysyl oxidase 20000
447078 AW885727 Hs 301570 ESTs 18400
429597 NM 003816 Hs 2442 a disintegnn and metalloprotemase doma 17700
409506 NM 006153 Hs 54589 NCK adaptor protein 1 17000
426471 M22440 Hs 170008 transforming growth fxtor, alpha 15800
413268 AL039079 Hs 75256 regulator of G-protem signalling 1 15500
419948 AB041035 Hs 93847 NADPH oxidase 4 14000
451807 W52854 Hs 27099 hypothetical protein FU23293 similar to 13900
442875 BE623003 Hs 23625 Homo sapiens clone TCCCTA00142 mRNA sequ 111 00
452795 AW392555 Hs 18878 hypothetical protein FU21620 10900
420831 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 10600
416283 NM 005429 Hs 79141 vascular endothelial growth fxtor C 9500
450221 AA328102 Hs 24641 cytoskeleton assxiated protein 2 9200
449101 AA205847 Hs 23016 G protein-coupled rxeptor 9200
442611 BE077155 Hs 177537 hypothetical protein DKFZp761B1514 8600
438533 AI440266 Hs 170673 ESTs, Weakly similar to T24832 hypotheti 8568
414132 AI801235 Hs 48480 ESTs 8500
447164 AF026941 Hs 17518 Homo sapiens cιg5 mRNA, partial sequence 8300
402047 AK001921 Hs 169575 hypothetical protein MGC2550 8000
414972 BE263782 Hs 77695 KIAA0008 gene product 7400
452943 BE247449 Hs 31082 hypothetical protein FU 10525 7400
416661 AA634543 Hs 79440 IGF-II mRNA binding protein 3 71 00
427099 AB032953 Hs 173560 odd Oz/ten-m homolog 2 (Drosophila mous 7019
449318 AW236021 Hs 78531 Homo εapiens, Similar to RIKEN cDNA 5730 66 25
418345 AJ001696 Hs 241407 seπne (or cysteine) proteinase iπhibito 6600
415076 NM 000857 Hs 77890 guanylate cyclase 1, soluble, beta 3 6400
414142 AW368397 Hs 150042 Homo sapiens cDNA FLJ14438 fis, clone HE 6300
432865 AI753709 Hs 152484 ESTs, Weakly similar to I38022 hypotheti 6000
431808 M30703 Hs 270833 amphiregulin (schwannoma deπved growth 5800
411750 BE562298 Hs 71827 KIAA0112 protein, homolog of yeast πbos 5700
418612 AB037788 Hs 224961 cleavage and polyadenylation spxific fa 5700
438394 BE379623 Hs 27693 peptidylprolyl isomerase (cyclophilm) I 5400
452198 AI097560 Hs 61210 ESTs, Weakly similar to I38022 hypotheti 5400
423020 AA383092 Hs 1608 replication protein A3 (14kD) 4900 422426 W79117 Hs 58559 ESTs 4900
406747 AI925153 Hs 217493 annexin A2 4600
445828 F05802 Hs 81907 ESTs 4600
431806 AF186114 Hs 270737 tumor necrosis factor (ligand) superfami 4400
452909 NM 015368 Hs 30985 panπexin 1 4395
432226 AW182766 Hs 273558 phosphate cytidylyltransferase 1, cholm 4300
458027 L49054 Hs 85195 myeloid leukemia factor 1 4300
443354 AW970672 Hs 9247 protein kinase, AMP-activated alpha 1 c 4300
416049 AI970536 Hs 16603 hypothetical protein FLJ13163 4200
431494 AA991355 Hs 298312 hypothetical protein DKFZp434A1315 4000
433859 AW896758 Hs 273789 ESTs 3800
426753 T89832 Hs 170278 ESTs 3700
400792 AA635062 Hs 50094 Homo sapiens mRNA, cDNA DKFZp434O0515 (f 3600
402034 3500
424073 U03493 Hs 138959 gap junction protein alpha 7, 45kD (con 3400
458424 AI084049 Hs 206761 ESTs 3400
435159 AA668879 Hs 116649 ESTs 3300
409269 AA576953 Hs 22972 hypothetical protein FU 13352 3200
444361 W76027 Hs 23920 hypothetical protein FLJ11105 3100
439128 AI949371 Hs 153089 ESTs 2920
420795 AA323037 Hs 128645 sorting nexin 16 2600
422505 AL120862 Hε 124165 ESTs 2500
434828 D90070 Hs 96 phorbol-12-myπstate-13 acetate induced 2400
410561 BE540255 Hs 6994 Homo εapieπε cDNA FLJ22044 fis, clone H 2210
423035 AW449679 Hε 156739 H sapienε XG mRNA (clone PEP11 ) 1900
417655 AA780791 Hε 14014 hypothetical protein FU14813 1900
414869 AA157291 Hs 21479 ubinucleiπ 1 1737
453049 BE537217 Hs 30343 ESTs 1600
417801 AA417383 Hs 82582 integπn, beta like 1 (with EGF-like rep 1400
435243 AW292886 Hs 261373 hypothetical protein dJ4340143 1300
431211 M86849 Hs 323733 gap junction protein beta 2, 26kD (conn 1080
407746 AK001962 Hε 38114 hypothetical protein FU11100 1000
416498 U33632 Hs 79351 potassium channel, subfamily K, member 1 960
414231 AI468004 Hs 278956 hypothetical protein FLJ12929 900
426227 U67058 Hs 168102 Human proteinase activated receptor-2 mR 809
439452 AA918317 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger pro 807
439999 AA115811 Hs 6838 ras homolog gene family, member E 807
417791 AW965339 Hs 111471 ESTs 804
436486 AA742221 Hs 120633 ESTs 723
432731 R31178 Hs 287820 fibronectin 1 700
429903 AL134197 Hs 93597 cyclm-dependent kinase 5, regulatory su 518
435039 AW043921 Hs 130526 ESTs 500
419743 AW408762 Hs 5957 Homo sapiens clone 24416 mRNA sequence 425
457001 J03258 Hs 2062 vitamin D (1,25- dihydroxyvitamin D3) re 424
450684 AA872605 Hs 25333 interleukin 1 rxeptor, type II 374
422440 NM 004812 Hs 116724 aldo-keto reductase family 1, member B10 319
458531 AA367718 Hs 159083 ESTs 300
416065 BE267931 Hs 78986 proliferating cell nuclear antigen 253
411388 X72925 Hs 69752 desmxollm 1 100
419750 AL079741 Hs 183114 Homo sapiens cDNA FU 14236 fiε, clone NT 100
429370 C19097 Hs 89709 glutamate-cysteine ligase, modifier subu 100
429921 AA526911 Hε 82772 collagen, type XI, alpha 1 100
449467 AW205006 Hs 197042 ESTs 100
453102 NM 007197 Hs 31664 fπzzled (Drosophila) homolog 10 100
453637 NM 002589 Hs 34073 BH-protxadheπn (brain-heart) 100
400289 X07820 Hs 2258 matnx metalloproteinase 10 (stromelyεin 51700
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial 61600
428368 BE440042 Hs 83326 matnx metalloproteinase 3 (stromelysin 22600
428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy 27800
450375 AA009647 Hε 8850 a disintegnn and metalloprotemase doma 5611
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph 26400
424717 H03754 Hs 152213 wmglesε-type MMTV integration site fami 12400
424735 U31875 Hs 272499 short-chain alcohol dehydrogenase family 100
420159 AI572490 Hs 99785 Homo sapiens cDNA FLJ21245 fis, clone C 100
415511 AI732617 Hs 182362 ESTs 100
406467 14100
422330 D30783 Hs 115263 epireguliπ 9800
452461 N78223 Hs 108106 transcnption fxtor 15900
415542 R13474 Hs 290263 ESTs, Weakly similar to I38022 hypotheti 100
413324 V00571 Hs 75294 corticotropin releasing hormone 100
431571 AW500486 Hs 180610 splicing fxtor prolme/glutamine πch ( 760
443211 AI128388 Hs 143655 ESTs 9900
451844 T61430 gb yc06a03 s1 Stratagene lung (937210) H 100
441877 AW273802 Hs 11340 hypothetical protein FLJ23047 3 00
439926 AW014875 Hs 137007 ESTs 279
432015 AL157504 Hs 158115 Homo sapiens mRNA, cDNA DKFZp586O0724 (f 9400
421103 AI625835 Hs 27104 Homo sapiens mRNA, cDNA DKFZp667D226 (fr 1 22
448062 AW295923 Hs 255472 KIAA1843 protein 1 00
432222 AI204995 gb an03c03 x1 Stratagene schizo brain S1 1 27
421577 BE465451 Hs 105925 single-minded (Drosophila) homolog 1 1 00
421187 NM 014721 Hs 102471 KIAA0680 gene product 500
408908 BE296227 Hs 250822 seπne/threonine kinase 15 8900
437214 BE092336 gb IL2 BT0734-240400-072 A12 BT0734 Homo 1 00 449773 R76294 Hs 302383 ESTs 100
443054 AI745185 Hs 8939 yes assxiated protein 65 kDa 9000
432097 X51730 Hs 2905 progesterone receptor 100
453216 AL137566 Hs 32405 Homo sapiens mRNA, cDNA DKFZp586G0321 (f 038
430184 AB013802 Hs 234790 contactin 5 100
432239 X81334 Hs 2936 matrix metalloprotemase 13 (collagenase 723
415025 AW207091 Hs 72307 ESTs 100
416575 W02414 Hs 38383 ESTs 100
443171 BE281128 Hs 9030 TONDU 092
424834 AK001432 Hs 153408 Homo sapiens cDNA FLJ 10570 fis, clone NT 2030
400844 060
409402 AF208234 Hs 695 cystatin B (stefin B) 196
412420 AL035668 Hs 73853 bone morphogenetic protein 2 138
435563 AF210317 Hs 95497 solute earner family 2 (facilitated glu 260
400751 134
436361 AA825814 Hs 149065 ESTs 092
455612 BE042896 Hs 274848 ESTs 081
447437 U07225 Hs 339 puπnergic receptor P2Y, G-protein coupl 155
404148 077
431089 BE041395 Hs 283676 ESTs, Weakly similar to unknown protein 100
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontiπ, 647
416658 U03272 Hs 79432 fibπllin 2 (congenital contrxtural ara 392
442994 AI026718 Hs 16954 ESTs 040
415327 H22769 gb ym54c02 r1 Soares infant brain 1NIB H 047
418624 AI734080 Hs 104211 ESTs 190
452850 H23230 Hs 22481 ESTs, Moderately εimilar to A46010 X-lm 054
401747 Homo εapiens keratin 17 (KRT17), 722
442432 BE093589 Hs 38178 hypothetical protein FLJ23468 510
418259 AA215404 Hs 137289 ESTs 128
432374 W68815 Hs 301885 Homo sapiens cDNA FLJ11346 fis, clone PL 813
403381 2100
420923 AF097021 Hs 273321 differentially expressed in hematopoieti 000
418216 AA662240 Hs 283099 AF15q14 protein 1129
444649 AW207523 Hs 197628 ESTs 010
407811 AW190902 Hs 40098 cysteine knot superfamily 1 , BMP antagon 464
402230 164
412530 AA766268 Hs 266273 hypothetical protein FLJ13346 297
447334 AA515032 Hs 91109 ESTs 062
432829 W60377 Hs 57772 ESTs 086
418686 Z36830 Hs 87268 aπnexm A8 844
421508 NM 004833 Hs 105115 absent in melanoma 2 268
410553 AW016824 Hs 255527 hypothetical protein MGC14128 222
419183 U60669 Hs 89663 cytochrome P450, subfamily XXIV (vitamin 7800
425721 AC002115 Hs 159309 uroplakin 1A 086
420370 Y13645 Hs 97234 uroplakin 2 087
417720 AA205625 Hs 208067 ESTs 583
437852 BE001836 Hs 256897 ESTs, Weakly similar to dJ3650121 [H sa 107
431753 X76029 Hs 2841 neuromedm U 700
402075 28600
423017 AW178761 Hs 227948 seπne (or cysteine) proteinase inhibito 36300
406687 M31126 Hs 272620 pregnancy spxific beta-1-glycoproteιn 9 481
405064 100
428664 AK001666 Hs 189095 similarto SALL1 (sal (Drosophιla)-lιke 200
441233 AA972965 Hs 135568 ESTs 100
456034 AW450979 gb UI-H-BI3-ala-a-12-0-Ul s1 NCI CGAP.Su 123
414221 AW450979 gb UI-H-BI3-ala-a-12-0-Ul s1 NCI CGAP.Su 065
412286 AW836233 gb QVO-DT0020-090200-107-a06 DT0020 Home 100
405484 100
407189 AA598927 gb ae37e03 ε1 Gessler Wilms tumor Homo ε 100
403085 100
408633 AW963372 Hs 46677 PRO2000 protein 246
435257 AA677026 Hs 191217 ESTε 100
410044 BE566742 Hs 58169 highly expressed in cancer, πch in leuc 100
445182 AW189787 Hs 147474 ESTs 050
417275 X63578 Hs 295449 parvalbumin 100
418406 X73501 Hs 84905 cytokeratin 20 100
421110 AJ250717 Hs 1355 cathepsin E 100
406081 213
449448 D60730 Hs 57471 ESTs 12300
451668 Z43948 Hs 326444 cartilage xidic protein 1 037
408243 Y00787 Hs 624 interleukin 8 335
436246 AW450963 Hs 119991 ESTs 5100
440304 BE159984 Hs 125395 ESTs 100
402778 100
406117 100
406360 7100
435347 AW014873 Hs 116963 ESTs 100
445550 AI242754 Hs 137306 ESTs 100
451359 H85334 Hs 336623 ESTs 100
419559 Y07828 Hs 91096 ring finger protein 100
429486 AF155827 Hs 203963 hypothetical protein FLJ10339 5800
425420 BE536911 Hs 234545 hypothetical protein NUF2R 100
402901 085 087
417715 AW969587 Hs 86366 ESTs 5 12
442577 AA292998 Hs 163900 ESTs 2 19
418867 D31771 Hs 89404 msh (Drosophila) homeo box homolog 2 1 54
426088 AF038007 Hs 166196 ATPase Class I type 8B member 1 1 11
412610 X90908 Hs 74126 fatty acid binding protein 6, ileal (gas 1 27
414683 S78296 Hs 76888 hypothetical protein MGC12702 067
431322 AW970622 gb EST382704 MAGE resequences, MAGK Homo 003
403903 087
405033 0 13
422282 AF019225 Hs 114309 apolipopratem L 2 13
425852 AK001504 Hs 159651 death receptor 6 TNF superfamily member 1 05
414987 AA524394 Hs 294022 hypothetical protein FLJ14950 2 59
430168 AW968343 Hs 24255 DKFZP43411735 protein 1 69
459702 AI204995 1 00
446082 AI274139 Hs 156452 ESTs 060
400843 076
417409 BE272506 Hs 82109 syndxan 1 1 78
439738 BE246502 Hs 9598 sema domain immunoglobulin domain (Ig), 1 20
437181 AI306615 Hs 125343 ESTs, Weakly similar to KIAA0758 protein 050
404875 080
436293 AI601188 Hs 120910 ESTs 1 40
422809 AK001379 Hs 121028 hypothetical protein FU10549 303
425883 AL137708 Hs 161031 Homo sapiens mRNA, cDNA DKFZp434K0322 (f 094
404977 Insulin like growth fxtor 2 (somatomedi 099
431347 AI133461 Hs 251664 insulin like growth fxtor 2 (somatomedi 1 10
413804 T64682 gb yc48b02 r1 Stratagene liver (937224) 085
432842 AW674093 Hs 334822 hypothetical protein MGC4485 1 20
420876 AA918425 Hs 177744 ESTs 085
422119 AI277829 Hs 111862 KIAA0590 gene product 071
400846 sortilin related rxeptor, L(DLR class) 075
421100 AW351839 Hs 124660 Homo sapienε cDNA FLJ21763 fis, clone C 401
430152 AB001325 Hs 234642 aquapoπn 3 1 74
402777 070
417151 AA194055 Hs 293858 ESTs 099
411248 AA551538 Hs 334605 Homo sapiens CDNA FU14408 fis clone HE 1 48
405034 AL035754 Hs 2474 toll like rxeptor 1 1 00
406671 AA129547 Hs 285754 met proto-oncogene (hepatocyte growth fa 18 68
431070 AW408164 Hs 249184 transcription factor 19 (SC1) 1 94
453134 AA032211 Hs 118493 ESTs 070
440006 AK000517 Hs 6844 hypothetical protein FLJ20510 2 19
418068 AW971155 Hs 293902 ESTs, Weakly similar to ISHUSS protein d 025
424364 AW383226 Hs 201189 ESTs, Weakly similar to G01763 atrophin- 274
439780 AL109688 gb Homo sapiens mRNA full length insert 307
438315 R56795 Hs 82419 ESTs 065
418937 T71508 Hs 13861 ESTs, Weakly similar to T42383 probable 1 18
444163 AI126098 gb qc54g07 x1 Soareε_plxenta_8to9weeks_ 085
444444 AI149332 Hs 14855 ESTs 059
407581 R48402 Hs 173508 P3ECSL 082
433078 AW015188 Hs 121575 Homo sapiens cDNA FLJ12231 fis, clone MA 092
417003 AL038170 Hs 80756 betame-hom∞ysteine methyltraπsferase 062
446024 AB040946 Hs 284227 KIAA1513 protein 092
427747 AW411425 Hs 180655 serme threonme kinase 12 1 42
419741 NM 007019 Hs 93002 ubiquitin earner protein E2 C 1 68
453883 AI638516 Hs 22630 cofxtor required for Sp1 transcπptiona 1 57
426847 S78723 Hs 298623 5 hydroxytryptamine (serotonin) rxeptor 008
446009 AI989885 Hs 231926 ESTs 1 00
457292 AI921270 Hs 334882 hypothetical protein FU 14251 098
415949 H10562 Hs 21691 ESTs 061
420281 AI623693 Hs 191533 ESTε 701
446673 NM 016361 Hs 15871 LPAP for lysophosphabdic xid phoεphata 072
450983 AA305384 Hs 25740 ER01 (S cerevisiae) like 221
414792 BE314949 Hs 87128 hypothetical protein FLJ23309 099
437553 AI829935 Hs 130497 ESTs, Weakly similar to MAT8_HUMAN CHLOR 054
421218 NM 000499 Hs 72912 cytxhrome P450, subfamily I (aromatic c 006
426900 AW163564 Hs 142375 ESTs 048
414595 AA641726 Hs 289015 hypothetical protein MGC4171 083
402305 089
453823 AL137967 gb DKFZp761D2315_r1 761 (synonym hamy2) 004
445911 AI985987 Hs 145645 ESTs, Moderately similar to ALULHUMAN A 049
436608 AA628980 Hs 192371 down syndrome cπtical region protein DS 065
423916 AW993496 Hs 17235 Homo sapiens clone TCCCIA00176 mRNA sequ 0 63
405932 1 76
401760 261
452240 AI591147 Hs 61232 ESTs 45300
421064 AI245432 Hs 101382 tumor nxrosis factor, alpha induced pro 1 04
421373 AA808229 Hs 167771 ESTs 1700
427239 BE270447 Hs 174070 ubiquitin carrier protein 1 16
435099 AC004770 Hs 4756 flap structure spxific endonuclease 1 1 68
422406 AF025441 Hs 116206 Opa interacting protein 5 3 19
413278 BE563085 Hs 833 interferon stimulated protein, 15 kDa 1 73
453389 BE273648 Hs 32963 cadhenn 6 type 2, K-cadheπn (fetal ki 1 00
454789 BE156314 gb QV0 HT0367-150200-114-d02 HT0367 Homo 1 00 434487 AF143867 Hs 337588 ESTs, Moderately similarto S65657 alpha 006
424008 R02740 Hs 137555 putative chemokine receptor, GTP-bind g 245
418067 AI127958 Hs 83393 cystalm E/M 1 41
441801 AW242799 Hs 86366 ESTs 14000
423536 L22075 Hs 1666 guanine nucleotide binding protein (G pr 245
410153 BE311926 Hs 15830 hypothetical protein FU12691 5800
400409 AF153341 Hs 283954 Homo sapiens winged helix/forkhead trans 1 17
452316 AA298484 Hs 61265 ESTs Moderately similarto G786.HUMAN P 086
427587 BE348244 Hs 202628 ESTs, Weakly similar to I78885 seπne/th 091
451161 AA211329 Hs 26006 hypothetical protein FU 10559 1 00
453204 R10799 Hs 191990 ESTs 1 13
437240 AA747537 gb nx85c05 s1 NCI_CGAP_GCB1 Homo sapienε 1 00
405531 092
440249 AI246590 Hs 337275 ESTε 1 32
426783 Z19084 Hs 172210 MUF1 protein 1 17
434192 AW387314 Hs 34371 ESTε 1 00
407881 AW072003 Hs 40968 heparan sulfate (glucosamine) 3 O sulfot 87 14
402001 3700
433967 AF113018 Hs 284302 PR01621 protein 1 00
451592 AI805416 Hs 213897 ESTε 10 00
422170 AI791949 Hs 112432 anti-Mulleπan hormone 067
408947 AL080093 Hs 49117 Homo sapiens mRNA, cDNA DKFZp564N1662 (f 1 00
452732 BE300078 Hs 80449 Homo sapiens, clone IMAGE 3535294, mRNA, 099
441940 AW298115 Hs 128152 ESTs 088
425048 H05468 Hs 164502 ESTs 033
444008 BE544855 Hs 220756 ESTs, Weakly similar to SFR4 HUMAN SPLIC 1 01
421307 BE539976 Hs 103305 Homo sapiens mRNA, cDNA DKFZp434B0425 (f 1 06
423853 AB011537 Hs 133466 slit (Drosophila) homolog 1 045
407846 AA426202 Hs 40403 Cbp/p300 interacting transxtivator, wit 062
410348 AW182663 Hs 95469 ESTs 1 00
419078 M93119 Hs 89584 insuliπoma-associated 1 004
414907 X90725 Hs 77597 polo (Drosophia) like kmase 1 04
441795 N58115 Hs 21137 AD024 protein 1000
418583 AA604379 Hs 86211 hypothetical protein 1 22
444342 NM 014398 Hs 10887 similar to lysosome assxiated membrane 10667
413385 M34455 Hs 840 indoleamme pyrrole 2,3 dioxygenase 230
441495 AW294603 Hs 127039 ESTs 044
417933 X02308 Hs 82962 thymidylate synthetase 248
412661 N32860 Hs 24611 ESTs, Weakly similar to I54374 gene NF2 1 00
411880 AW872477 gb hm30f03 x1 NCI_CGAP_Thy4 Homo sapiens 1 00
417771 AA804698 Hs 82547 retinoic acid receptor responder (tazaro 1 44
430034 X60155 Hs 227767 zinc finger protein 41 1 00
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 287
454417 AI244459 Hs 110826 tπnucleotide repeat containing 9 054
429257 AW163799 Hs 198365 23-bιsphosphoglycerate mutase 227
417599 AA204688 Hs 136201 ESTs 1 01
438366 AA805760 Hs 303567 ESTs 1 00
438746 AI885815 Hs 184727 ESTs 1 47
409691 T89983 Hs 246042 Homo sapiens, clone MGC 5437, mRNA, comp 1 00
408827 AW275730 Hε 254825 ESTs 1 00
414735 BE468016 Hs 281904 ESTs 1 00
422278 AF072873 Hs 114218 frizzled (Drosophila) homolog 6 521
412719 AW016610 Hs 129911 ESTs 49400
417034 NM 006183 Hs 80962 neuroteπsin 1 00
430486 BE062109 Hs 241551 chloπde channel, calcium xtivated, fam 2336
407788 BE514982 Hs 38991 S100 calcium binding protein A2 698
413753 U17760 Hs 75517 laminin, beta 3 (nicem (125kD), kalinm 750
424012 AW368377 Hs 137569 tumor protein 63 kDa with strong homolog 977
425650 NM.001944 Hs 1925 desmoglein 3 (pemphigus vulgaπs antigen 44500
412140 AA219691 Hs 73625 RAB6 interacting, kinesm-like (rabkmes 1393
423673 BE003054 Hε 1695 matrix metalloproteinase 12 (mxrophage 1277
452838 U65011 Hs 30743 preferentially expressed antigen in mela 4500
418663 AK001100 Hs 41690 desmxollin 3 1089
409632 W74001 Hs 55279 senne (or cysteine) proteinase inhibito 629
429610 AB024937 Hs 211092 LUNX protein, PLUNC (palate lung and nas 088
406690 M29540 Hs 220529 carcmoembryonie antigen-related cell ad 38 31
421948 L42583 Hs 334309 keratin 6A 36 81
431846 BE019924 Hs 271580 uroplakin 1B 1 37
424098 AF077374 Hs 139322 small proline πch protein 3 8 85
453964 AI961486 Hs 12744 ESTs 040
446856 AI814373 Hs 164175 ESTs 1 16
443648 AI085377 Hs 143610 ESTs 2 15
408522 A1541214 Hs 46320 Small proliπe-πch protein SPRK [human, 439
431384 BE158000 gb MR2-HT0377-150200-202-e03 HT0377 Homo 1 18
422158 L10343 Hs 112341 protease inhibitor 3, skin derived (SKAL 422
435505 AF200492 Hs 211238 ιnterleukιπ-1 homolog 1 16400
417366 BE185289 Hs 1076 small proline nch protein 1B (cornifin) 985
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheππ (placenta 559
441020 W79283 Hs 35962 ESTs 576
423217 NM_000094 Hs 1640 collagen, type VII, alpha 1 (epidemiolys 1 97
448733 NM.005629 Hs 187958 solute camerfamily 6 (neurotransmitte 1 09
444371 BE540274 Hs 239 forkhead box M1 244
422168 AA586894 Hs 112408 S100 calcium binding protein A7 (psoπas 8 39 429259 AA420450 Hs 292911 ESTs, Highly similar to S60712 band 6-pr 253
426440 BE382756 Hs 169902 solute camerfamily 2 (facilitated glu 1 67
437044 AL035864 Hs 69517 cDNA for differentially expressed C016 g 230
423662 AK001035 Hs 130881 B cell CLL/lymphoma 11 A (zmo finger pro 1 04
428484 AF104032 Hs 184601 solute carrier family 7 (cationic ammo 3 11
401781 11 07
401780 954
429211 AF052693 Hs 198249 gap junction protein, beta 5 (conπexm 3 1 62
417389 BE260964 Hs 82045 midkme (πeuπte growth-promoting factor 1 12
423634 AW959908 Hs 1690 hepaπn binding growth fxtor binding pr 94700
417515 L24203 Hs 82237 ataxia telangixtasia group D-assxiated 2.79
441362 BE614410 Hs 23044 RAD51 (S cerevisiae) homolog (E coli Re 3 16
440704 M69241 Hs 162 insulin like growth fxtor binding prote 1 08
425322 U63630 Hs 155637 protein kinase, DNA-xtivated, catalytic 520
431221 AA449015 Hs 286145 SRB7 (suppressor of RNA polymerase B, ye 253
449003 X76342 Hs389 alcohol dehydrogenase 7 (clasε IV), mu o 7200
431009 BE149762 Hs 48956 gap junction protein, beta 6 (connexin 3 19 96
409103 AF251237 Hs 112208 XAGE-1 protein 047
417542 J04129 Hs 82269 progestagen-associated endometπal prote 066
428471 X57348 Hs 184510 εtratifin 339
418004 U37519 Hs 87539 aldehyde dehydrogenase 3 family member 1 61
414761 AU077228 Hs 77256 enhancer of zeste (Drosophila) homolog 2 231
451541 BE279383 Hs 26557 plakophilin 3 1 82
418203 X54942 Hs 83758 CDC28 protein kinase 2 560
447343 AA256641 Hs 236894 ESTs, Highly similar to S02392 alpha 2-m 278
437016 AU076916 Hs 5398 guanine monphosphate synthetase 201
429612 AF062649 Hs 252587 pituitary tumor-transforming 1 2 18
449230 BE613348 Hs 211579 melanoma cell adhesion molxule 258
446989 AK001898 Hs 16740 hypothetical protein FLJ 11036 463
457819 AA057484 Hs 35406 ESTε, Highly similar to unnamed protein 225
410555 U92649 Hs 64311 a disintegnn and metalloproteinase doma 11 88
430677 Z26317 Hs 94560 desmoglein 2 1 38
424687 J05070 Hs 151738 matrix metalloprotemase 9 (gelatmase B 209
414430 AI346201 Hs 76118 ubiquitin carboxyl-terminal esterase L1 1 09
422963 M79141 Hs 13234 ESTs 228
418462 BE001596 Hs 85266 integnn, beta 4 1 40
450832 AW970602 Hs 105421 ESTs 1331
410274 AA381807 Hs 61762 hypoxia inducible protein 2 1 25
408353 BE439838 Hs 44298 mitochondnal πbosomal protein S17 1 89
458933 AI638429 Hs 24763 RAN binding protein 1 1 54
439394 AA149250 Hs 56105 ESTs 389
418478 U38945 Hs1174 cyclm-dependent kinase inhibitor 2A (me 1 77
453633 AA357001 Hs 34045 hypothetical protein FLJ20764 1 52
446269 AW263155 Hs 14559 hypothetical protein FLJ10540 3 11
422765 AW409701 Hs 1578 baculoviral IAP repeat-containing 5 (sur 2 10
436481 AA379597 Hε5199 HSPC150 protein similar to ubiquitin-con 1 84
440325 NM.003812 Hs7164 a disintegnn and metalloproteinase doma 061
439606 W79123 Hs 58561 G protein-coupled receptor 87 30300
453884 AA355925 Hs 36232 KIAA0186 gene product 1055
452834 AA581322 Hs4213 hypothetical protein MGC16207 1 38
451743 AW074266 Hε 23071 ESTs 290
413129 AF292100 Hs 104613 RP42 homolog 238
406974 M57293 gb Human parathyroid hormone-related pep 1 00
413281 AA861271 Hs 222024 transcription fxtor BMAL2 592
444781 NM 014400 Hs 11950 GPI-anchored metastasis-assxiated prote 218
416819 U77735 Hs 80205 pιm-2 oncogene 1 01
451320 AW118072 Hs 89981 dixylglycerol kmase, zeta (104kD) 067
418543 NM 005329 Hs 85962 hyaluronaπ synthase 3 1 19
454034 NM 000691 Hs575 aldehyde dehydrogenase 3 family, member 255
425397 J04088 Hs 156346 topoisomerase (DNA) II alpha (170kD) 306
413004 T35901 Hs75117 interleukin enhancer binding fxtor 2, 4 1 64
407634 AW016569 Hs 136414 UDP-GlcNAc betaGal beta-1,3-N-xetylgluc 704
415817 U88967 Hs78867 protein tyrosine phosphatase, receptor-t 20300
435013 H91923 Hs 110024 NADH ubiqumone oxidoreductase MLRQ subu 1 33
430337 M36707 Hs 239600 calmodulin-like 3 1 32
419121 AA374372 Hs 89626 parathyroid hormone-like hormone 81 00
448993 AI471630 Hs8127 KIAA0144 gene product 1 03
440138 AB033023 Hε 318127 hypothetical protein FLJ 10201 2800
421817 AF146074 Hε 108660 ATP-binding cassette, sub-family C (CFTR 1 24
425245 AI751768 Hs 155314 KIAA0095 gene product 1 40
430393 BE185030 Hs 241305 estrogen-responsive B box protein 1 55
420462 AF050147 Hε 97932 choπdromodulm I precursor 1 00
418678 NM 001327 Hs 167379 cancer/testis antigen 082
428182 BE386042 Hs 293317 ESTs, Weakly similar to GGC1.HUMAN G ANT 1 00
427335 AA448542 Hs 251677 G antigen 7B 091
409420 Z15008 Hs 54451 laminin, gamma 2 (nicem (100kD), kalini 653
438956 W00847 Hs 135056 Human DNA εequence from clone RP5-850E9 1 35
421917 AB028943 Hs 109445 KIAA1020 protein 094
404440 3857
409582 R27430 Hs 271565 ESTε 3 19
415669 NM 005025 Hs78589 senne (or cysteine) proteinase inhibito 245
433091 Y12642 Hε3185 lymphocyte antigen 6 complex, Ixus D 1 61
408122 AI432652 Hs42824 hypothetical protein FLJ10718 1 95 408380 AF123050 Hs 44532 diubiquitm 7 23
437412 BE069288 Hs 34744 Homo sapiens mRNA, cDNA DKFZp547C136 (fr 1 35
449976 H06350 Hs 135056 Human DNA sequence from clone RP5 850E9 081
446102 AW168067 Hs 252956 ESTs 1 03
428479 Y00272 Hs 184572 cell division cycle 2, G1 to S and G2 to 13700
422487 AJ010901 Hs 198267 mucin 4, tracheobroπchial 791
423761 NM 006194 Hs 132576 paired box gene 9 3600
436291 BE568452 Hs 5101 protein regulator of cytokinesis 1 535
423725 AJ403108 Hs 132127 hypothetical protein L0C57822 20700
440659 AF134160 Hs 7327 claudin 1 306
434360 AW015415 Hε 127780 ESTs 389
437915 AI637993 Hs 202312 Homo sapienε clone N11 NTera2D1 teratoca 1 28
438898 AI819863 Hs 106243 ESTs 1 73
441553 AA281219 Hs 121296 ESTs 1 47
418379 AA218940 Hs 137516 fidgetiπ like 1 4042
436396 AI683487 Hε 152213 wingless type MMTV integration site fami 1425
429413 NM 014058 Hs 201877 DESC1 protein 5 17
422283 AW411307 Hs 114311 CDC45 (cell division cycle 45, S cerevis 1 95
415380 F07953 Hs 16085 putative G protein coupled receptor 0 18
423849 AL157425 Hs 133315 Homo sapiens mRNA, cDNA DKFZp761J1324 (f 1 00
446292 AF081497 Hs 279682 Rh type C glycoprotein 209
429538 BE182592 Hs 11261 small proline-rich protein 2A 6 14
447289 AW247017 Hs 36978 melanoma antigen, family A, 3 1 00
428004 AA449563 Hs 151393 glutamate-cysteine ligase, catalytic sub 4400
415091 AL044872 Hs 77910 3-hydroxy-3-methylglutary!-Coenzyme A sy 149 00
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient, yeast, h 12700
408572 AA055611 Hs 226568 ESTs, Moderately similar to ALU4_HUMAN A 2000
404996 14700
438915 AA280174 Hs 285681 Williams-Beuren syndrome chromosome regi 1 00
453922 AF053306 Hs 36708 budding uninhibited by benzimidazoles 1 5400
424046 AF027866 Hs 138202 εerme (or cysteine) proteinase inhibito 13900
430563 AA481269 Hs 108660 ATP binding cassette, sub family C (CFTR 2200
438702 AI879064 Hs 54618 ESTs 1 00
444378 R41339 Hs 12569 ESTs 1 00
433485 AI493076 Hs 201967 aldo keto reductase family 1, member C2 41 00
407839 AA045144 Hs 161566 ESTs 750
439223 AW238299 Hs 250618 UL16 binding protein 2 339
409041 AB033025 Hs 50081 KIAA1199 protein 24500
429228 AI553633 Hs 337139 ESTs 1089
409757 NM.001898 Hs 123114 cystatin SN 3 19
411089 AA456454 Hs 183418 cell division cycle 2-lιke 1 (PITSLRE pr 078
436511 AA721252 Hs 291502 ESTs 0 23
449207 AL044222 Hs 23255 nucleopoπn 155kD 1 68
453331 A1240665 Hs 8895 ESTs 521
409935 AW511413 Hs 278025 ESTs 075
428969 AF120274 Hs 194688 artemin 1 17
445443 AV653838 Hs 322971 ESTs 1 00
407137 T97307 gb ye53h05 s1 Soares fetal liver spleen 11 42
401785 276
412723 AA648459 Hs 335951 hypothetical protein AF301222 10700
450701 H39960 Hs 288467 Homo sapienε cDNA FU12280 fis, clone MA 2 17
405770 242
439453 BE264974 Hs 6566 thyroid hormone rxeptor iπterxtor 13 424
420783 AI659838 Hs 99923 Ixtin, galactoside-bmding, soluble, 7 450
414774 X02419 Hs 77274 plasminogen xtivator, urokmase 1 95
424629 M90656 Hs 151393 glutamate-cysteine ligase, catalytic sub 1 44
437789 AI581344 Hs 127812 ESTs, Weakly similar to T17330 hypotheti 1 00
454098 W27953 Hs 292911 ESTs, Highly similar to S60712 band 6-pr 1 33
453968 AA847843 Hs 62711 Homo sapienε, clone IMAGE 3351295, mRNA 1 11
427441 AA412605 Hs 178053 SPANX family, member C 500
403478 078
400842 0 16
441525 AW241867 Hs 127728 ESTs 079
452865 AI924046 Hs 119567 ESTs, Weakly similar to A47582 B-cell gr 1 50
405646 1 05
427260 AA663848 gb ae70b06 s1 Stratagene schizo brain S1 079
431413 AA504777 Hs 105293 ESTε 1 00
401994 3 25
402420 005
404298 064
404927 8800
434105 AW952124 Hε 13094 preεenilmε assxiated rhomboid like pro 096
436961 AW375974 Hs 156704 ESTs 358
429563 BE619413 Hs 2437 eukaryotic translation initiation factor 092
426067 AW664691 Hs 97053 ESTs 097
428810 AF068236 Hε 193788 nitric oxide synthase 2A (inducible, hep 066
426897 AW976570 Hs 97387 ESTs 1 29
443892 AI889572 Hs 134791 ESTs 1 00
413223 AI732182 Hs 191866 ESTs 079
413691 AB023173 Hs 75478 ATPase, Class VI, type 11B 1 51
423934 U89995 Hs 159234 forkhead box E1 (thyroid transcnption f 259
425159 NM 004341 Hs 154868 carbamoyl phosphate synthetase 2 aspart 1 39
420758 AW297536 Hs 33053 ESTs 089 423816 AL031985 Hs 133034 hypothetical protein 1 00
447534 AW953935 Hs 30837 ESTs 1 88
451919 W05086 Hs 114256 ESTε, Weakly similar to I78885 seπne/th 0 11
409228 R16811 Hs 22010 ESTs Weakly similar to 2109260A B cell 092
403715 089
428645 AA431400 Hs 98729 ESTs, Weakly similar to 2017205A dihydro 1 00
425734 AF056209 Hs 159396 peptidylglycine alpha amidating monooxyg 3700
436839 AA767346 Hs 291614 ESTs 1 00
413582 AW295647 Hs 71331 hypothetical protein MGC5350 5900
413573 AI733859 Hs 149089 ESTε 7800
430686 NM 01942 Hs 2633 desmoglein 1 12708
438993 AA828995 gb od77b08 s1 NCI_CGAP_Ov2 Homo εapiens 1 00
448243 AW369771 Hs 52620 integnn, beta 8 13300
444783 AK001468 Hε 62180 anillin (Drosophila Scraps homolog), act 23200
426427 M86699 Hs 169840 TTK protein kinase 6600
422956 BE545072 Hs 122579 hypothetical protein FLJ10461 14800
445537 AJ245671 Hs 12844 EGF-like-domam, multiple 6 4075
453392 U23752 Hs 32964 SRY (sex determining region Y) box 11 1300
424905 NM.002497 Hs 153704 NIMA (never in mitosis gene a) related k 10600
400298 AA032279 Hs 61635 six transmembrane epithelial antigen of 15900
415989 AI267700 Hs 317584 ESTs 19600
408000 L11690 Hs 620 bullous pemphigoid antigen 1 (230/240kD) 3244
453160 AI263307 Hs 239884 H2B histone family, member L 700
409361 NM 005982 Hs 54416 sine oculis homeobox (Drosophila) homolo 4 13
416208 AW291168 Hs 41295 ESTs, Weakly similar to MUC2.HUMAN MUCIN 4500
TABLE 24B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accessions Genbank xcession numbers
Pkey CAT number Accessions
411880 1263110 1 AW872477 BE088101 T05990
412296 1288043 1 AW936233AW936272
413804 1390710 1 T64682 BE168190 BE168256
414221 142696.1 AW450979 AA136653 AA136656 AW419381 AA984358 AA492073 BE168945 AA809054 AW238038 BE011212 BE011359 BE011367
BE011368 BE011362 BE011215 BE011365 BE011363
415327 1534137.1 H22769 R35182 Z43545 F05783 N92089 H71928
427260 276598 1 AA663848 AA400100 AA401424
431322 331543 1 AW970622 AA503009 AA502998 AA502989 AA502805 T92188
431384 33264.1 BE158000 BE157999 H75671 H70965 C18895 BE386512 BE385815 BE390298 A1341995 BE074534 AA055592 AA132265 AI733757
AA134504 BE145037 AA055887 BE070191 R66492 AW858018 AW858058 AW817057 AW862031 AW861688 AW862029 AW858805 AW858792
AW862028AW858017AW819164AW853698 AI522161 AW854789 AW817408 BE152005 AI732411 AA133084
432222 343347 1 AI204995 AW827539 AW969908 AW440776 AA528756
437214 434730 1 BE092336 BE092259 BE092497 BE092051 AA746882 AI336378
437240 435139 1 AA747537 BE089068 BE089070
438993 467651 1 AA828995 AA834879 AI926361
439780 47673 1 AL109688 R23665 R26578
444163 593658 1 A! 126098 Al 184746 Al 1 8521
451844 888230 1 T61430 AI820546 A1821336
453823 982526 1 AL137967 BE064160 BE064186
454789 1234742 1 BE156314 BE156316AW820750
456034 142696 1 AW450979 AA136653 AA136656 AW419381 AA984358AA492073 BE168945AA809054AW238038 BE011212 BE011359 BE011367
BE011368 BE011362 BE011215 BE011365 BE011363
TABLE 24C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in thiε column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exonε were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand N position
400751 7331445 Minus 35395-35533
400842 1927148 Pluε 90462-90673
400843 9188605 Plus 5863-5970,7653-7784,8892-9023,9673-9807,10634-10789,15254-15403,23827-23958
400844 9188605 Plus 24746-24872,25035-25204
400846 9188605 Plus 39310-39474
401486 7341763 Plus 32585-32756,36281-36540,40791-40933,44018-44179
401747 9789672 Minus 118596-118816,119119-119244,119609 119761,120422-120990,130161-130381,130468 130593,131097-131258,131866-
131932,132451-132575,133580-134011
401760 9929699 Plus 83126 83250,85320-85540,94719 95287
401780 7249190 Minus 28397-28617,28920-29045,29135-29296,29411-29567,29705-29787,30224-30573
401781 7249190 Minus 83215-83435,83531-83656,83740 83901,84237-84393,84955-85037,86290 86814
401785 7249190 Minuε 165776-165996,166189-166314,166408 166569,167112-167268,167387-167469,168634-168942
401994 4153858 Minus 42904-43124,43211-43336,44607-44763,4519945281,46337-46732
402001 9501818 Plus 68052-68223 402034 7684482 Minus 8622786451
402075 8117407 Plus 121907-122035,122804-122921,124019124161,124455-124610,125672-126076
402230 9966312 Minus 29782-29932
402305 7328724 Plus 40832-41362
402420 9796339 Plus 129750129919
402777 9588235 Plus 126786126948
402778 9588235 Plus 128560-128702
402901 8884222 Minus 175426175667
403085 8954241 Plus 165035165334,165420165713
403381 9438267 Minus 2600926178
403478 9958258 Plus 116458116564
403715 7239669 Plus 8512885292
403903 7710671 Minus 101165102597
404148 9863703 Plus 78218-7841879571-79709
404298 9944263 Minus 73591-73723
404440 7528051 Plus 8043081581
404875 9801324 Plus 9658896732,97722-97831
404927 7342002 Plus 6869069563
404977 3738341 Minus 43081-43229
404996 6007890 Plus 37999-3814538652-38998,39727-39872,40557-40674,42351-42450
405033 7107731 Minus 142358142546
405064 7658416 Plus 81207-81416
405494 8050952 Minus 70284-70518
405531 9665194 Plus 35602-35803
405646 4914350 Plus 741-969
405770 2735037 Plus 61057-62075
405932 7767812 Minus 123525-123713
406081 9123861 Minus 3811538691
406117 9142932 Plus 54304-54584
406360 9256107 Minus 7513-7673
406467 9795551 Plus 182212182958
TABLE 25A 691 genes upregulated in head and neck cancer relative to normal body tissues
Table 25A lists about 691 genes upregulated in head and neck cancer relative to normal body tisεueε that are likely to encode proteins amenable to modulation by small molxules peptides, or antibodies These genes were selected from 59680 probesets on the Eos/Affymetπx Hu03 Genechip array Gene expresεion data for exh probeset obtained from this analysis was expreεsed aε average intensity (Al), a normalized value reflecting the relative level of mRNA expression The protein products of these genes often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death domain, 7tm phosphatase, or lon.transporter) Certain predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar xcesεion number, GenBank xceεsion number
UniGenelD UniGene number
Pred Prot Domains Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain =M, likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280) UniGene Title UniGene gene title
R1 85th percentile of head and nxk cancer Als divided by the 50th percentile of normal tissue Als, where the 10th percentile of all normal tissue Als was subtrxted from both the numerator and denominator
Pkey, ExAccn, UnigenelD, Unigene Title, Pred Prot Domains, R1
422168, AA586894, Hs 112408, S100 calcium-binding protein A7 (psoπaε, efhand,S_100,TM=M,SS=N, 4625 408522, AI541214, Hs 46320, Small proline πch protein SPRK [human, , none.Cornifin, 4037
417366, BE185289, Hs 1076, small prol e-πch protein 1B (cornifin), Cornιfin,TM=M,SS=N, 3894
401781, , , Target Exon, filameπt,TM=M,SS=N, 2974
422158, L10343, Hs 112341, protease inhibitor 3, skin denved (SKAL, wap,TM=M,SS=Y, 2954
401780, , , NM.005557* Homo sapienε keratin 16 (fxa, filament,filament, 2858 424098, AF077374, Hs 139322, small proline-πch protein 3, Cornιfin,TM=M,SS=N, 2855
421948, L42583, Hs 334309, keratin 6A, filament RhoGAP,DUF286,bZIP,Tropomyosιπ,tubulιn,DUF164,TBCA Collagen,TM=M,SS=N, 2574
428471, X57348, Hs 184510, stratifin, 14-3-3,TM=M,SS=N, 2365
417079, U65590, Hs 81134, interleukin 1 rxeptor antagonist, IL1„ 21 02
421574, AJ000152, Hs 105924, defensm, beta 2, Defensιn_beta,TM=M,SS=M, 2083 409601, AF237621, Hs 80828, keratin 1 (epidermolytic hyperkeratosiε), filament,bZIP,UvrD-helιcase,TBCA,TM=M,SS=N, 2072
433091, Y12642, Hs 3185, lymph∞yte antigen 6 complex, locus D, UPAR_LY6,toxιn,Actιvιn_recp,TM=M,SS=Y, 1963
446292, AF081497, Hs 279682, Rh type C glycoprotein, Ammonιum_transp,FxCD,TM=Y,SS=M, 19 53
420783, AI659838, Hs 99923, Ixtm, galactoside binding, soluble, 7 , Gal bιnd_lxtιn,TM=M,SS=N, 19 12
407788, BE514982, Hs 38991, S100 calcium-binding protein A2, efhand,S_100,S_100,efhand, 1793 416091 , AF295370, Hs 283082, defensm, beta 3, Defeπsm_beta,TM=M,SS=M, 1763
431211, M86849, Hs 323733, gap junction protein, beta 2, 26kD (conn, connexιn,TM=Y,SS=M, 1694
429259, AA420450, Hs 380088, Plakophilin, none.none, 1492
417515, L24203, Hs 82237, ataxia telangixtasia group D-assxiated, zf-B_box,zf-UBR1,TM=M,SS=N, 1475
423634, AW959908, Hs 1690, hepann-bindmg growth fxtor binding pπ none,TM=M,SS=M, 1445 418007, M13509, Hs 83169, matrix metalloprotemase 1 (interstitial, hemopexm,Peptιdase_M10,Astxιn,PG_bιndιπg_1„ 1302
409632, W74001, Hs 55279, serine (or cysteine) proteinase inhibito, serpm,, 1282
406621 , X57809, Hs 181125 immunoglobulin lambda locus, ig HSP70,Ppx-GppA,TM=M,SS=N, 1281
431958, X63629, Hs 2877, cadhenn 3, type 1, P-cadheππ (placenta, cadheπn.Cadheπn.C term,TM=Y,SS=M, 1245
446921, AB012113, Hs 16530, small inducible cytokine subfamily A (Cy, IL8„ 11 71 401760 , , Target Exon, none.bromodomam, 11 68
407839, AA045144, Hs 161566, ESTs, cadheππ.cadheπn, 11 65
454034, NM.000691, Hs 575, aldehyde dehydrogenase 3 family, member , aldedh,, 11 56
444781, NM_014400, Hs 11950 GPI anchored metastasis assxiated prote, UPAR_LY6,lactamase_B, 11 31
Figure imgf000288_0001
429554, NM.012275, Hs 207224, ιπterleuk|n 1, delta IL1,TM=M,SS=N, 5 14 421508, NMJ04833 Hs 105115, absent in melanoma 2, PAAD_DAPIN,HIN,TM=M,SS=N, 5 13 439979, AW600291, Hs 6823, hypothetical protein FU10430, noπe,TM=M,SS=N, 5 11 427099, AB032953, Hs 173560, odd Oz/ten m homolog 2 (Drosophila, ous, NHL,TM=M SS=N 5 11 428227, AA321649, Hε 2248, εmall inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 508
436396, AI683487, Hs 152213, wingless type MMTV integration site fa i, wnt.none, 507 406690, M29540 Hs 220529, carcmoembryonie antigen related cell ad, ιg,TM=M,SS=M, 505 453905, NM.002314 Hs 36566, UM domain k ase 1, pkιnase,LIM,PDZ,zf PARP,TM=M,SS=N, 504 414035, Y00630, Hs 75716, senne (or cysteine) proteinase inhibito, serpiπ,, 500 413219, AA878200, Hs 118727, Homo sapienε cDNA FU13692 fis, clone PL, HLH,death,TNFR_c6,Acyl CoA.hydro, 496
421506, BE302796, Hs 105097, thymidine kinase 1, soluble, TK,TM=M,SS=N, 493 412140, AA219691, Hs 73625, RAB6 interacting, kmesin-like (rabkmes, kιnesιπ,Trapomyosιn,TM=M,SS=N, 492 445537, AJ245671, Hs 12844, EGF-like-domam, multiple 6, EGF.MAM,, 491
428953, AA306610 Hs 348183, tumor nxrosis fxtor receptor superfami, 60s_πbosomal,Rιbosomal_L10,TNFR_c6,DEAD„ 490 436553, AW407157, Hs 181125, immunoglobulin lambda Ixus, ιg,HSP70,Ppx-GppA,TM=M,SS=N, 489
447343, AA256641 , Hs 236894, ESTs, Highly similar to S02392 alpha-2-m, none.none, 484 430024, AI808780, Hs 227730, integnn, alpha 6, integnn A,FG-GAP,TM=Y,SS=M, 481 439706, AW872527, Hs 59761, ESTs, Weakly εimilar to DAP1.HUMAN DEATH, none.none, 480 444371, BE540274 Hε 239 forkhead boxMI, Fork_head,TM=M,SS=N, 475 428582, BE336699, Hs 185055, BENE protein, none,TM=Y,SS=M, 474
419586, BE379320, Hs 91448, MKP-1 like protein tyrosine phosphatase, DSPc,, 469
431630, NM.002204 Hs 265829, integπn, alpha 3 (antigen CD49C, alpha , FG-GAP,Rhabd jlycop ιntegπn_A,TM=Y,SS=M 4 69 422310, AA316622 Hs 98370, cytochrome P450, subfamily IIS, polypept none,pkιnase,fn3,ιg, 468 418067, AI127958 Hs 83393, cystatm E/M, cystatin,, 466 414774, X02419, Hs 77274, plaεminogen activator, urokmase, kππgle,trypsm,planLthιonms„ 464
456534, X91195, Hs 100623, phospholipase C, beta 3, neighbor pseudo, LIM,PDZ,pkιnase„ 462 410418, D31382, Hs 63325 transmembrane protease, serine 4, Idl.recepLa trypsιn,TM=Y,SS=M, 460 417866, AW067903, Hε 82772, collagen, type XI, alpha 1, Collagen,COLFI,TSPN,lamιnιn_G,CorA„ 460 438113, AI467908, Hε 8882, ESTs 7tm_1 none, 460 418140, BE613836, Hs 83551, microfibπllar assxiated protein 2, none,TM=M,SS=M, 457
408380, AF123050, Hs 44532, diubiquitin, ubιquιtιn,TM=M,SS=N, 455
422627, BE336857 Hs 118787, transforming growth factor, beta-induced, Fasciclin.ABCJran ABC_membrane,GTP_EFTU,TM=M,SS=M, 450 425247, NM 005940 Hs 155324, matnx metalloprotemase 11 (stromelyεm, hemopexιn,Peptιdaεe_M10„ 450 418558, AW082266, Hs 86131, Fas (TNFRSF6)-ass∞ιated via death domai, death.DED,, 4 49 408482, NM.000676, Hs 45743, adenosine A2b receptor, 7tm_1 ,TM=Y,SS=M, 448
414166, AW888941, Hs 75789, N-myc downstream regulated, DEAD,helιoase_C,rrm,Ndr,Cys_knot,TIL,vwa,vwc,vwd,IQ,Rlla,abhydrolase,TGF- beta,DUF139,TPR,DSPc,tsp_1,Rιbosomal_S21,rvp,TM=M,SS=N, 447 416178, AI808527, Hε 192822, εerologieally defined breast cancer and, none,TM=M,SS=N, 447 411789, AF245505, Hs 72157, Adlican, ig LRR,LRRNT,LRRCT,TM=M,SS=M, 447 414561, AI064813, Hs 195155, Homo sapiens ammo xid transport syεtem, Aa_trans,TM=Y,SS=N, 447
422765, AW409701, Hs 1578, bxuloviral IAP repeat-containing 5 (sur, BIR,TM=M,SS=N, 445 427557, NM 02659, Hs 179657, plasminogen xtivator, urokmase rxepto, UPAR_LY6,ET,PLA2_ιnh„ 443 418322, AA284166, Hs 84113, cyclm-dependent kmase inhibitor 3 (CDK, Y_phosphatase,DSPc,TM=M,SS=N, 442 409041, AB033025, Hs 50081, Hypothetical protein, XP.051860 (KIAA119, none,TM=M,SS=M, 441 406908, Z25437, , gb H sapienε protein tyroεine kinase gen, none.none, 440
450701, H39960, Hs 288467, hypothetical protein XP 098151 (leucine-, none.LRRCT.LRR, 440 409213, U61412, Hs 51133, PTK6 protein tyrosine kinase 6, SH2,SH3,pkmase,TM=M,SS=N, 438
429500, X78565, Hs 289114, hexabrxhion (tenascm C, cytotxtm), EGF,fn3,fibπnogeπ_C,toxιn_2,Keratιπ_B2,TM=M,SS=Y, 438 448569, BE382657, Hs 21486, signal transducer and xtivator of trans, SH2,STAT,STAT_bιnd,STAT_prot,TM=M,SS=N, 432 423725, AJ403108, Hs 132127, hypothetical protein LOC57822, none,TM=M,SS=N, 432
411573, AB029000, Hs 70823, KIAA1077 protein, Sulfatase,TM=M,SS=N, 431 408243, Y00787, Hs 624, interleukin 8, HLH,PAS,IL8,TM=M,SS=N, 431 418738, AW388633, Hs 6682, εolute earner family 7, (cationic ammo, none.none, 430 437897, AA770561, Hε 146170, hypothetical protein FLJ22969, zf-DHHC,none, 429 424247, X14008, Hs 234734, lysozyme (renal amyloidosis), lys,ιg,FAD_Synth,ldh,ldh_C,pkιnase„ 429
414821, M63835, Hs 77424, Fc fragment of IgG, high affinity la, re, ιg,TM=Y,SS=M, 429 404996, , , Target Exon, Peptιdase_C1,TM=M,SS=M, 429
416539, Y07909, Hs 79368, epithelial membrane protein 1, PMP22_Claudιn,oxιdored_q5_N,TM=Y,SS=M, 428 409142, AL136877, Hs 50758, SMC4 (structural maintenance of chromoso, ABC_tran,M,SMC_N,SMC_C,DUF164,none, 425 421532, AW138207, Hs 146170, hypothetical protein FLJ22969, Armadιllo_seg,HEAT,TM=M,SS=N, 425
424503, NM.002205, Hε 149609, integπn, alpha 5 (fibronxtiπ receptor,, ιπtegπn_A,FG-GAP,TM=Y,SS=N, 4 24 414809, AI434699, Hε 77356, transferπn rxeptor (p90, CD71), PA,TM=Y,SS=N, 424 439720, AI935202, Hs 31181, Homo sapiens cDNA FLJ23230 fiε, clone C, none,SDF,εugar_tr, 423 437044, AL035864, Hs 69517, differentially expressed in Faπcom's an, none,TM=M,SS=M, 423 409956, AW103364, Hs 727, inhibin, beta A (xtivm A, xtivm AB a, TGF-beta,TGFb_propeptιde,Tub„ 420
439453, BE264974, Hs 6566, thyroid hormone rxeptor interxtor 13, AAA,ABC_tran,CoaE,TM=M,SS=N, 420 417389, BE260964, Hs 82045, midkine (neunte growth-promoting fxtoπ PTN_MK,TM=M SS=Y, 4 19 407137, T97307, , gb ye53h05 s1 Soares fetal liver spleen , GDA1_CD39,none, 4 18 419235, AW470411, Hs 288433, neurotnmm, none.none, 4 18 410290, AA402307, Hs 322844, hypothetical protein DKFZp564A176, Sema,PSI,TIG,ιntegπn B,TM=Y,SS=M, 4 18
456906, AF117646, Hs 156637, Cas-Br-M (munne) xtrapic retroviral tr; zf-C3HC4,Cbl_N,Cbl_N2,Cbl_N3,TM=M,SS=N, 4 17 448775, AB025237, Hs 388, nudix (nucleoside diphosphate linked moi, NUDIX,TM=M,SS=M, 4 17 400288, X06256, Hs 149609, integnn, alpha 5 (fibronectin receptor,, ιntegπn_A,FG-GAP,TM=Y,SS=N, 4 14 409799, D11928, Hs 76845, phosphosenne phosphatase-like, Hydrolase,TM-M,SS=N, 4 13 445417, AK001058, Hs 12680, a disintegnn like and metalloprotease w, tsp_1,Repralysιn,Pep_M12B_propep,none, 4 12
433895, AI287912, Hs 3628, mitogen xtivated protein kinase kinase , pkmase.zf C4,CNH,ERM,TM=M,SS=N, 4 12 424490, AJ278016 Hs 55565, ankyπn repeat domain 3, ank,pkιnase,TM=M,SS=N, 409 419121, AA374372, Hs 89626, parathyroid hormone-like hormone, none.none, 408 416602, NM.006159 Hs 367895, Protein kinase C-biπdmg protein NELL2, EGF,vwc,TSPN„ 407 424008, R02740, Hs 137555, putative chemokine receptor, GTP-bmding, 7tm_1,TM=Y,SS=M, 407
427747, AW411425, Hs 180655, seππe/threoπiπe kinase 12, pkιnase,TM=M,SS=N, 406 427490, Z95152, Hs 178695, mitogen activated protein kinase 13, pkιπase,TM=M,SS=N, 403 439738, BE246502, Hs 9598, sema domain, immunoglobulin domain (Ig) , Sema,PSI,ιntegπn_B,TM=Y,SS=N, 402 414883, AA926960, Hs 348669, CDC28 protein kmase 1, CKS„ 402
413186, AU077141, Hs 374548, solute carrier family 16 (monxarboxylic, sugar tπTM=Y,SS=M, 401 418203, X54942, Hs 83758, CDC28 protein kinase 2, CKS , 401 406906 Z25424, , gb H sapiens protein seπne/threonine ki, none.none, 398 450375, AA009647, Hs 352537, a disintegnn and metalloproteinase doma, Reprolysin,Pep_M12B_propep,disintegrin Reprolysιn,Pep_M12B_propep,dιsιntegπn, 398
410687, U24389, Hs 65436, lysyl oxidase like 1, Lysyl.oxidase , 396 410342, R31350, Hε 743 Fc fragment of IgE, high affinity I, rec, ITAM,TM=Y,SS=M, 3 95 425849, AJ000512, Hs 296323, serum/glucocorticoid regulated kinase, pkιnase,pkιnase_C,TM=M SS=M, 395 417433, BE270266 Hs 82128, 5T4 oπcofetal trophoblast glycoprotein, LRR,LRRNT,LRRCT,TM=Y,SS=M, 395 427792, M63928, Hs 180841, tumor necrosis factor receptor superfami, SRP14,TNFR_c6„ 393
407792, AI077715, Hs 39384, putative secreted ligand homologous to f, none,TM=M,SS=Y, 3 91 424441, X14850, Hs 147097, H2A histone family, member X, hιstone,CBFD_NFYB_HMF„ 3 91 415989, AI267700, Hs 351201, ESTs, none.none, 390 423189, M59371, Hs 171596 EphA2, fn3,pkιnase,SAM,EPH_lbd,TM=Y,SS=M, 390 443859, NM.013409, Hs 9914, follistatin, kazal,, 389
429612, AF062649, Hs 252587, pituitary tumor-transforming 1, none,, 389 419073, AW372170, Hs 183918, Homo sapiens cDNA FLJ12797 fis, clone NT, dealh,ZU5„ 388 450684, AA872605, Hs 25333, interleukin 1 receptor, type II, ιg,TM=Y,SS=M, 3 88 428450, NM 014791, Hs 184339, KIAA0175 gene product, KA1,pkιnase,TM=M,SS=N, 386 413441 , AI929374, Hs 75367, Src-like adapter, SH2,SH3,TM=M,SS=N, 384
437763, AA469369, Hs 5831 , tissue inhibitor of metalloprotemase 1 , TIMP,pkιnase,DAG_PE-bιnd RBD, 383 436291, BE568452 Hs 344037, protein regulator of cytokinesis 1, πoπe,TM=M,SS=N, 382 417512 X76534, Hs 82226, glycoprotein (transmembrane) nmb, PKD,TM=Y,SS=M, 381 427647, W19744, Hε 180059, Homo sapiens cDNA FU20653 fis, clone KA, none.pkmase, 380 431629, AU077025 Hs 265827, interferon, alpha-mducible protein (clo, none,TM=M,SS=Y, 380
434699, AA643687, Hs 149425, Homo sapiens cDNA FU11980 fis, clone HE, Nucleosιde_tra2,none, 3 80 430378, Z29572, Hs 2556, tumor necrosiε factor rxeptor εuperfami, IL2„ 379 428157, AI738719, Hs 198427, hexokmase 2, hexokιnase,hexokιnase2,none, 378
409512, AW979187, Hs 293591, melanoma differentiation assxiated prot, DEAD,helιcase_C,CARD,TM=M,SS=N, 378 417720, AA205625, Hs 208067, ESTs, none.none, 377
439237, AW408158, Hs 318893, ESTs, Weakly similar to A47582 B-cell gr, Fuπn like pkιnase,Recep_L_domaιπ,YLP,none, 377 449029, N28989, Hs 22891 , solute carrier family 7 (cationic ammo , aa_permeases,TM=Y,SS=M, 376 413436, AF238083, Hs 68061, sphmgosme kinase 1, DAGKc,TM=M,SS=N, 375
416714, AF283770, Hs 79630, CD79A antigen (immunoglobulin-associated, ig.lTAM Zπ_clus,TM=Y,SS=M, 374 413281, AA861271, Hs 222024, transcnption factor BMAL2, HLH.PAS,, 374
436481, AA379597, Hs 5199, HSPC150 protein similarto ubiquitin-con, UQ_con,TM=M,SS=N, 374 431890, X17033, Hs 271986, integnn, alpha 2 (CD49B, alpha 2 subuni, vwa ιntegnn_A,FG-GAP,TM=Y,SS=M 374 424118, BE269041, Hs 140452, cargo selxtion protein (mannoεe 6 phoεp, peπlipm,, 373 426471, M22440, Hs 170009, transforming growth factor, alpha, EGF,TM=M,SS=M, 372 422487, AJ010901, Hs 198267, mucin 4, trxheobranchial, EGF,vwd,AMOP„ 372
450125, AA005418, Hs 158186, ESTs, CIDE-N,7tm_1,noπe, 371 427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lllb, r, ιg,TM=Y,SS=M, 370 444006, BE395085, Hs 334762, type I transmembrane protein Fn14, ldl_rxepLa,PKD,MHC_l,TM=M,SS=Y, 370 422010, AA302049, Hs 31181, Homo sapiens cDNA FLJ23230 fis, clone C, none.SDF.sugar.tr, 370 418969, W33191, Hs 28907, hypothetical protein FU20258, SH3,TM=M,SS=N, 369
415817, U88967, Hs 78867, protein tyrosine phosphatase, rxeptor-t, fn3,Y_phosphatase,carb_anhydrase,TM=Y,SS=M, 368 443759, BE390832, Hs 134729, FXYD domain-containing ion transport reg, ATP1G1_PLM_MAT8,TM=Y,SS=M, 3 68 452344, AI264357, Hs 55405, hypothetical protein MGC16212, Sulfate_tranεp,STAS„ 368 439625, AF086453, Hs 58611 , ESTs, Fork_head,glycolytιc_enzy,Na_sulph_εymp, 366 426227, U67058, Hε 154299, Human proteinase xtivated receptor-2 R, 7tm_1 ,TM=Y,SS=M, 366
452363, AI582743, Hs 94953, Homo sapiens, Similar to complement comp, C1q,Collagen„ 365
447365, BE383676, Hs 334, Rho guanine nucleotide exchange fxtor (, SH3,PH,RhoGEF,TM=M,SS=N, 364
418883, BE387036, Hs 1211, xid phosphatase 5, tartrate resiεtant, Metallophos,TM=M,SS=M, 364 438707, L08239, Hs 5326, ammo xid system N transporter 2, porcu, ACAT,MBOAT,TM=Y,SS=M, 364 422596, AF063611, Hs 118633, 2'-5'-olιgoadenylate synthetase-lιke, ubiquitin,, 363
449318, AW236021 , Hs 78531 , Homo sapiens, Similar to RIKEN cDNA 5730, none,TM=M,SS=N, 362
438746, AI885815, Hs 184727, Human melanoma-assxiated antigen p97 (m, transferπn,Guanylate_kιn,PDZ,SH3, 362
446291, BE397753, Hs 14623, interferon, gamma-inducible protein 30, GILT,TM=M SS=Y, 362
452696, AI826645, Hs 211534, ESTs, ArfGap,PH,ank,Guanylate kιπ,PDZ,SH3, 360 407634, AW016569, Hs 136414, UDP-GlcNAc betaGal beta-1,3-N-xetylgluc, Galactosyl_T,TM=M,SS=Y, 359
423575, C18863, Hs 163443, intron of penostin (OSF-2os), Fascicliπ.none, 359
421391, AW304350, Hs 191958, immunoglobulin superfamily rxeptor tran, ig.none, 358
419452, U33635, Hs 90572, PTK7 protein tyrosine kinase 7, ig pkιnase,TM=Y,SS=M, 358
419912, AF249745, Hs 6066, Rho guanine nuclxtide exchange fxtor (, SH3,PH,RhoGEF,TM=M,SS=N, 358 431457, NM.012211, Hs 256297, integπn, alpha 11, FG-GAP,vwa,TM=Y,SS=M, 357
430379, AF134149, Hs 240395, potassium channel, subfamily K, member 6, ιon_trans,TM=Y,SS=M, 355
418526, BE019020, Hε 85838, solute camerfamily 16 (monxarboxylic, none,TM=Y,SS=M, 355
441362, BE614410, Hs 23044, RAD51 (S cerevisiae) homolog (E coli Re, none,, 353
426500, NM.014638, Hs 170156, KIAA0450 gene product, C2,PI-PLC-Y,TM=M,SS=N, 3 53 429556, AW139399, Hs 314807, ESTs, none,TM=M,SS=N, 352
449101, AA205847, Hs 23016, G protein-coupled rxeptor, 7tm_1,TM=Y,SS=M, 352
432636, AA340864, Hs 278562, claudin 7, PMP22_Claudιn,TM=Y,SS=M, 351
433470, AW960564, Hs 351316, transmembrane 4 superfamily member 1 , πoπe,TM=Y,SS=M, 351
452203, X57522, Hs 352018, transporter 1 , ATP binding cassette, sub, ABC_tran,ABC_membrane,SRP54,Thymιdylate kιn,TM=Y,SS=M, 349 425566, AW162943, Hs 250618, UL16 binding protein 2, ldl_rxepLa,PKD,MHC_l,TM=M,SS=Y, 348
402447, , , C1000201 gι|204416|gb|AAA02627 1| (L0519, none,TM=Y,SS=M, 348
431183, NM.006855, Hs 250696, KDEL (Lys-Asp-Glu Leu) endoplasmic retic, ER_lumeπ_rxept,TM=M,SS=M, 348
448988, Y09763, Hs 22785, gamma aminobutyπc acid (GABA) A rxepto, Neur chan.LBD.Neur chan_memb,TM=Y,SS=M, 348
415323, BE269352, Hs 949, neutrophil cytosolic factor 2 (65kD, chr, SH3,TPR,TM=M,SS=N, 348 425003, AF119046, Hs 154149, apuπnic/apyπmidinic eπdonucleaselAPEX , Troponιn,Exo_endo_phos,IQ,TM=M,SS=N, 347
424909, S78187, Hs 153752, cell division cycle 25B, Rhodanese , 344
446051, BE048061, Hε 37054, ephnn A3, Ephπn A_deamm,dsrm,z-alpha, 343
418641, BE243136, Hs 86947, a disintegnn and metalloprotemase doma, dismtegnn,Reprolysin,Pep_M12B_propep,EGF,TM=Y,SS=M, 342 417426, NM.002291, Hs 82124, laminin beta 1, laminin_EGF,laminin_Nterm,integrm_B„ 342 411263, BE297802, Hs 69360, kinesm like 6 (mitotic centromere assoc, kιnesιn,TM=M,SS=N, 342 430044 AA464510, Hs 152812, ESTs, none none 342
425289, AW139342, Hs 155530, interferon, gamma-induαble protein 16, PAAD_DAPIN,HIN„ 339 425354, U62027, Hs 155935 complement component 3a rxeptor 1, 7tm_1,TM=Y,SS=M, 339
428293, BE250944, Hs 183556, solute carrier family 1 (neutral ammo a elF6,SDF,TM=M,SS=N, 3 39 443648 AI085377, Hs 143610, ESTs, Forkjiead none, 339
418869, AW516565 , gb xq01d05 x1 Soares_NHCeC_cervιcal_tumo, none,RasGAP,WW,IQ, 3 38 432179, X75208 Hs 2913 EphB3 EPH_lbd,fn3,pkιπase,SAM,TM=Y,SS=M, 338 418918, X07871 , Hs 89476, CD2 antigen (p50), sheep red blood cell , ιg,TM=Y,SS=M, 338
414368, W70171, Hs 75939, undine monophosphate kinase, PRK,CoaE„ 337
408716, AI567839, Hs 151714, Homo sapiens mRNA for KIAA1769 protein, , UvrD helicase.RNB Runt,TM=M,SS=N, 337 457001, J03258, Hs 2062, vitamin D (1,25- dihydroxyvitamin D3) re, hormone_rx,zf C4,Metallothιo_5,TM=M,SS=N, 3 37 422283, AW411307, Hs 114311 , CDC45 (cell division cycle 45, S cerevis, CDC45,TM=M,SS=N, 337 421817, AF146074, Hε 108660, ATP-binding cassette, sub-family C (CFTR, Fasci in ABC_tran,ABC_membraπe,GTP_EFTU,TM=M,SS=M, 336
400298, AA032279, Hs 61635, six transmembrane epithelial antigen of , noπe,TM=Y,SS=N, 335 428385, AF112213, Hs 184062, putative Rab5 interacting protein, SH2.SH3,, 333 400261, , Hε 1802, Eos Control, ig.MHC ll_beta,TM=Y,SS=M, 333 410024, AW191024, Hs 55016, hypothetical protein FU21835, SH3,TM=M,SS=N, 332 412584, X54870, Hs 74085, DNA segment on chromosome 12 (unique) 24, none,lxtιn_c, 332
416065, BE267931, Hs 78996, proliferating cell nuclear antigen, PCNA,PCNA_C,TM=M,SS=N, 331 426437, BE076537, Hs 169895, ubiquitin-conjugatmg enzyme E2L6, Armadιllo_seg UQ_coπ,none, 331 426840, BE244217, Hs 172690, dixylglycerol kmase, alpha (80kD), efhand,DAG_PE-bιnd,DAGKa,DAGKc,DC1,TM=M,SS=N, 331 434419, AL040606, Hs 296938, dual spxificity phosphatase 7, DSPc,TM=M,SS=N, 331 418758, AW959311, Hs 172012, hypothetical protein DKFZp434J037, pkιπase,RI01,TM=M,SS=N, 3 31
424779, AL046851, Hs 153053, CD37 antigen, transmembrane4,TM=Y,SS=M, 331 423973, AF038461, Hs 136574, arachidoπate 12-lιpoxygenase, 12Rtype, lιpoxygenase,PLAT,TM=M,SS=N, 330 421733, AL119671 , Hs 1420, fibroblast growth fxtor rxeptor 3 (xh, ιg,pkιπase,TM=Y,SS=M, 330 449027, AJ271216, Hs 22880, dipeptidylpeptidase III, Peptιdase_M49,EGF,ιg,Neuregulιπ,TM=M,SS=N, 328 423778, Y09267, Hs 132821, flavin containing mon∞xygenase 2, FMO lιke,pyr_redox,TM=Y,SS=M, 3 28
426457, AW894667, Hs 380138, chimenn (chimaeπn) 1, DAG_PE-bιnd,RhoGAP,SH2,TM=M,SS=N, 328 435523, T62849, Hs 11090, membrane spanning 4-domaιns, subfamily A, none,TM=Y,SS=M, 327 431886, L77964, Hs 271980, mitogen xtivated protein kinase 6, pkmase,TM=M,SS=N, 327 430397, AI924533, Hs 105607, bicarbonate transporter related protein , HC03_cotransp,TM=Y,SS=N, 327 425322, U63630, Hε 155637, protein kinase, DNA-xtivated, catalytic, PI3_PI4_kιnase,FAT,FATC,TM=M,SS=N, 326
446006, NM.004403, Hs 13530, deafness, autosomal dominant 5, none,TM=M,SS=M, 3 26 444783, AK001468, Hs 62180, anillin (Drosophila Scraps homolog), xt, PH.none, 325 422278, AF072873, Hs 114218, fπzzled (Drosophila) homolog 6, Fz,Fnzzled,7tm_2,TM=Y,SS=M, 3 25 405932, , , C15000305 gι|3806122|gb|AAC69198 1| (AF0, ras,TM=M,SS=N, 325 400205, , Hs 81848, NM 006265* Homo sapiens RAD21 (S pombe), DUF173,, 325
432874, W94322 Hs 279651, melanoma inhibitory activity, SH3,TM=M,SS=Y, 324 412942, AL120344, Hs 75074, mitogen xtivated protein kmase-xtivat, pkιnaεe,TM=M,SS=N, 323 435472, AW972330, Hs 283022, tπggeπng receptor expressed on myeloid, ιg,TM=M,SS=M, 322 439285, AL133816, Hε 47860, hypothetical protein FLJ20093, ιg,pkιnase,LRR,LRRNT,LRRCT,none 322 410434, AF051152, Hs 63668, toll like rxeptor 2, LRR,LRRCT,TIR,TM=M,SS=M, 322
427318, AF186081, Hs 175783 zinc transporter, Zιp,TM=Y,SS=M, 3 22 436075, BE090176, Hs 179902, transporter-like protein, none,TM=Y,SS=M, 322 428698, AA852773, Hs 334838, KIAA1866 protein, none.NA.NA, 322 448888, AW196663, Hs 200242, caspase recruitment domain protein 6, CARD,TM=M,SS=N, 322 415149, X12451, Hs 78056, cathepsin L, Peptidase C1„ 321
423393, R37772, Hs 21420, p21-xtιvated protein kinase 6, pkιnase,PBD,TM=M,SS=N, 321 424618, L29472, Hs 1802, major histocompatibitity complex, clasε , ιg,MHC_ll_beta,TM=Y,SS=M, 320 438564, AA381553, Hε 198253, major hist ompatibility complex, clasε , ιg,MHC_ll_alpha,none, 320 456181, L36463, Hε 1030, ras inhibitor, RA,SH2,VPS9,TM=M,SS=N, 320 418613, AA744529, Hs 86575, itogen-xtivated protein kinase kinase , pkmase,CNH,TM=M,SS=N, 3 19
440682, AW362152, Hε 27181, nuclear rxeptor binding fxtor-2, cyclιπ,bZIP,TM=M,SS=N, 318 415010, NM.004203, Hs 77783, membrane-ass∞iated tyrosine- and threon, ank pkιnase,UPF0073„ 3 16 419216, AU076718, Hs 164021, εmall inducible cytokine subfamily B (Cy, IL8„ 3 16 450737, AW007152, Hs 63325, transmembrane protease, seπne 4, trypsιn,ldl_recepLa,none, 3 16 426395, BE151985, Hs 355669, hypothetical protein FLJ23316, pkmase.none, 3 15
412939, AW411491, Hs 75069, eukaryotic translation elongation fxtor, none.none, 3 15 433376, AI249361, Hs 74122, caεpase 4, apoptosis-related cysteine pr; CARD,ICE_p10,lCE_p20„ 3 15 410668, BE379794, Hs 159651, hypothetical pratem, death,TNFR_c6,TM=Y,SS=M, 3 15 431441, U81961, Hs 2794, sodium channel, nonvoltage-gated 1 alpha, ASC,TM=Y,SS=N, 3 15 432251, AW972983, Hs 232165, polycythemia rubra vera 1, cell surfxe , none,TM=M,SS=M, 3 15
407844, AW073716, Hs 8037, ESTs, transmembraπe4,πone, 3 14 408634, AW407254, Hs 356216, calmodulin 2 (phosphorylaεe kinase, delt, none none, 3 14 423061 , AI290473, Hs 44807, ESTs, ιntegnn_B,Sema,PSI,TIG,none, 3 14 438974, AF089816, Hs 6454, chromosome 19 open reading frame 3, PDZ„ 3 13 431236, AV656840, Hs 285115, interleukin 13 rxeptor, alpha 1, fn3,TM=Y,SS=M, 3 13
425394, AA356730, Hs 323949, kangai 1 (suppression of tumoπgenioity , traπsmembrane4,none, 3 13 429336, AB005038, Hs 199270, cytochrome P450, subfamily XXVIIB (25-hy, p450„ 3 13 449230, BE613348, Hs 356392, melanoma cell adhesion molxule, ιg,ιsodh,Rιbosomal_L6,F-box,TM=Y,SS=M, 3 13 429305, AF095727, Hs 287832, myelin protein zero like 1, ιg,transmembrane4,TM=Y,SS=M, 3 12 419034, NM.002110, Hs 89555, hemopoietic cell kinase, SH2,SH3,pkιnase,TM=M,SS-N, 3 12
417386, AL037228, Hs 301957, D123 gene product, NUDIX,secY,E1 dehydrog,transket_pyπTM=Y,SS=M 3 11 419138, U48508, Hs 89631, ryanodine receptor 1 (skeletal), ion trans.SPRY.RYDR ITPR,RyR,MIR,TM=Y,SS=N, 3 11 440006, AK000517, Hs 6844, NALP2 protein, PYRIN-Containing APAF1-lι, AAA.NB ARC,PAAD_DAPIN,NA,NA, 3 10 406467, , , Target Exon, efhand,Acyltransferase,none, 3 10 422956, BE545072, Hs 122579, ECT2 protein (Epithelial cell transformi, BRCT,RhoGEF,TM=M,SS=N, 3 10
417771, AA804698, Hs 82547, retinoic acid receptor responder (tazaro, none.none, 309 437016, AU076916, Hs 5398, guanine monphosphate synthetase, PHD.SET zf-
CXXCEGF.ank πotch,WW,FCH,GATase,GMP synLC,Oxludιn,YEATS,metalthιo,EB,heme_1,RCC1,ZZ,FeThRed_A ENTH,Band_41,HECT TM=M,SS=N, 309 441384, AA447849 Hs 288660, retinoic acid induced 3, 7tm_3,πone 309 416636, N32536, Hs 42645, solute carrier family 16 (monocarboxylic, none none 309 416498, U33632, Hs 79351, potassium channel, subfamily K, member 1, ιon_traπs,TM=Y,SS=M 309 426108, AA622037 Hs 166468, programmed cell death 5, DUF122,TM=M,SS=N, 308 414806 D14694, Hs 77329, phosphatidylseπne synthase 1, PSS,TM=Y,SS=M, 308
402233, , , NM.030760* Homo sapienε endothelial diff, 7tm_1,TM=Y,SS=M, 307 430066, AI929659, Hs 237825, signal recognition particle 72kD, TPR AIRC,SAICAR_syπt 307 425367, BE271188 Hs 155975, protein tyrosine phosphatase, receptor t, none TM=M,SS=Y, 3 06 434263, N34895, Hs 79187, ESTs, ig.noπe, 306 443907, AU076484, Hs 9963, TYRO protein tyrosine kinase binding pro, none,TM=M,SS=Y, 305
409378, U42387, Hs 54426, pancreatic polypeptide receptor 1, 7tm_1,TM=Y,SS=M, 305 410165, BE560228, Hs 71869, apoptosis-associated spxk-like protein , PAAD_DAPIN,CARD,TM=M,SS=N, 305 440270, NM.015986, Hs 7120, cytokine receptor-like molecule 9, fn3„ 305 449003, X76342, Hs 389, alcohol dehydrogenase 7 (class IV), mu o, adh_zιπc,TM=M,SS=N, 305 420189, AW296380, Hs 95821 , osteoclast stimulating factor 1, SH3,ank„ 305
429732, U20158, Hs 2488, lymphxyte cytosolic protein 2 (SH2 doma SH2„ 305
421541, NM 003942, Hs 105584, ribosomal protein S6 kinase, 90kD, polyp, pkιnase,pkmase_C,TM=M,SS=N, 304 415444, BE247295, Hs 78452, solute earner family 20 (phosphate tran, PH04,LIM,TM=M,SS=N, 303 425118, AU076611, Hs 154672, methylene tetrahydrafolate dehydrogenase, myb DNA- bιndιng,THF_DHG_CYH,THF_DHG_CYH_C,CAP_GLY,AAA,LON,Peptιdase_C9,bZIP,M,xaπ_ur_permease,HC03_cotransp,TM=M SS=N, 303
449048, Z45051 , Hs 22920, similar to S68401 (cattle) glucose indue, Lamp,TM=M,SS=M, 303 413869, NM.000878 Hs 75596, interleukin 2 receptor, beta, none,TM=Y,SS=M, 302 442875, BE623003, Hs 23625, Homo sapiens clone TCCCTA00142 mRNA sequ, K_tetra,DUF51,none, 302 436576, AI458213, Hs 77542, ESTs, 7tm_1 ,DnaJ, 302 446269, AW263155, Hs 14559, hypothetical protein FU10540, noπe,TM=M,SS=N, 302
418870, AF147204, Hs 89414, chemokine (C-X-C motif), receptor4 (fus, 7tm 1,7tm_2,TM=Y,SS=M, 301 421379, Y15221, Hs 103982, small inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 300 421267, BE314724, Hs 103081, πbosomal protein S6 kinase, 70kD, polyp, pkιnaεe,pkιnaεe_C,TM=M,SS=N, 300 409705, M37762, Hs 56023, brain derived neurotrophic fxtor, NGF„ 299 429903 AL134197, Hs 93597, cyclin dependent kinase 5, regulatory su, CDK5_xtιvator,none, 298
430696, AA531276, Hs 59509, ESTs, pkιnase,PP2C,πone, 298
418299, AA279530, Hs 83968, integnn, beta 2 (antigen CD18 (p95), ly, ιntegrιn_B,EGF,PSI,TM=Y,SS=M, 297 410026, AI912061, Hs 55016, hypothetical protein FLJ21935, none.none, 297 448733, NM.005629 Hs 187958, solute carrier family 6 (neurotransmitte, SNF,TM=Y,SS=N, 297 432562, BE531048, Hs 278422, DKFZP586G1122 protein, zf-C2H2,TM=M,SS=N, 297
453035, AW581943, Hs 334, Rho guanine nucteotide exchange fxtor (, none.none, 297 427315, AA179949, Hs 175563, Homo sapiens mRNA, cDNA DKFZp564N0763 (f, none,spxtπn,SH3,PH CH, 297 431941, AK000106, Hs 272227, Homo sapiens cDNA FU20099 fis, clone CO, pkinase.Funn lιke,Rxep_L_domaιn,none, 296 441389, AF134838, Hs 7835, endocytic rxeptor (mxrophage mannose r, fn2,tedιn_c TM=Y,SS=M, 295 412276, BE262621, Hs 73798, macrophage migration inhibitory fxtor (, MIF sugar.tr.none, 294
427359, AW020782 Hs 79881 , Homo sapienε cDNA FU23006 fis, clone L, 7tm 1, none, 294
402558, , , C1000201 gι|204416|gb|AAA02627 1| (L0519, none,TM=Y,SS=M, 294
425852, AK001504, Hs 159651 , death rxeptor 6, TNF superfamily member; death,TNFR_c6,TM=Y,SS=M, 294
442080, AW444761 , Hs 72901 , ESTs, aπk„ 294 450447, AF212223, Hs 25010, hypothetical protein P15-2, NTF2,TM=M,SS=N, 293
444809, BE207568 Hs 208219, xulospaπm, transmembrane4,TM=Y,SS=N, 293
449843, R85337, Hs 24030, solute carrier family 31 (copper transpo, none,TM=Y,SS=M, 293
416110, Z42262, Hs 322844, hypothetical protein DKFZp564A176, Sema,PSI,TIG,ιntegππ_B,TM=Y,SS=M, 293
453768, BE382670 Hs 198511, Homo sapiens mRNA, cDNA DKFZp761l177 (fr; arf,G-alpha,πone, 292 414825, X06370, Hs 77432, epidermal growth fxtor rxeptor (avian , Fuπn-lιke,pkιnase,Rxep_L_domaιn,TM=M,SS=M, 292
421429, NM.014922 Hs 104305, death effector filament-forming Ced-4-lι, LRR,PAAD_DAPIN,AAA,CARD,NB-ARC,NA,NA, 292
434826, AF155661, Hs 22265, pyruvate dehydrogenase phosphatase, PP2C,none, 291
451292, AB037716, Hs 26204, KIAA1295 protein, SH3,TM=M,SS=N, 291
422127, AW504286, Hs 112049, SET binding factor 1, dDENN,DENN,GRAM,PH„ 291 419508, AW997938, Hs 90786, ATP-binding caεεette, sub-family C (CFTR, ABC_tran,ABC_membrane,TM=Y,SS=M, 290
430451, AA836472, Hs 297939, cathepsin B, Peptιdase_C1,pro_ιsomerase„ 290
424046, AF027866, Hs 138202, serine (or cysteine) proteinase inhibito, serpm,TM=M,SS=N, 289
414907, X90725, Hs 77597, polo (Drosophιa)-lιke kinase, Rιbosomal_L37x,pkmase,POLO_box,tRNA-synt_1b,dynamιn,dyπamm_2,GED bZIP,M„ 289
429619, AL120751, Hs 211568, eukaryotic translation initiation fxtor; none.none, 289 413879, AA132961, Hs 212533, Homo sapiens cDNA FU22572 fis, clone H, none.none, 289
417018, M16038, Hs 80887, v-yes-1 Yamaguchi εarcoma viral related , SH2,SH3,pkιnaεe,TM=M,SS=N, 289
422610, AF153820, Hs 1547, potassium inwardly-rectifying channel, s, 1RK,TM=Y,SS=N, 289
405556, , , homeodomaiπ-interxting protein kinase 3, trypsιn,TM=M,SS=N, 289
423804, AW403448, Hs 1706, interferon-stimulaled transcnption fxt, IRF,zf-C3HC4,IBR zf-RanBP,TM=M,SS=N, 289 425262, D87119, Hs 155418, GS3955 protein, pkinase,, 288
422599, BE387202 Hs 118638, non-metastatic cells 1, protein (NM23A) , NDK,PH,Oxysterol_BP„ 288
452888, AW955454, Hs 30942, ephπn-B2, Ephππ,fn2,TM=Y,SS=M, 288
414703, BE243877, Hs 380063, ATPase, Na? transporting, beta 3 polypep, Na K-ATPase,TM=Y,SS=M, 287
444143, AW747996, Hs 160999, ESTs, Moderately similar to A56194 throm, Bd-2,noπe, 286 413472, BE242870, Hs 75379, solute camerfamily 1 (glial high affi, SDF,TM=Y,SS=M, 286
458039, AA835884, Hs 130685, leukotnene b4 rxeptor (chemokine rxep, CIDE-N,none, 286
434417, AL110157, Hs 3843, Homo sapiens mRNA, cDNA DKFZp586F2224 (f, DSPc.noπe, 286
425802, Y14838 , chemokine-like rxeptor 1, 7tm_1,none, 286
403112, , , Target Exon, efhaπd,C2,PH,PI-PLC-Y,PI-PLC-X„ 286 435563, AF210317, Hs 95497, solute camerfamily 2 (facilitated glu, sugar tr;TM=Y,SS=N, 285
442117, AW664964, Hs 128899, ESTs, hypothetical protein for IMAGE 447, none.none, 2 84
457819, AA057484, Hs 35406 FU20522 Hypothetical protein FU20522, none.none, 284
456629, AW891965 Hs 367942 histone deacetylase 3, HSP90,HATPase_c,zf C2H2,PHD,none, 2 83
408873, AL046017, Hs 356216, calmodulin 2 (phosphorylase kinase, delt, none.none, 283 446947, AF146747, Hs 232165, polycythemia rubra vera 1, cell surface , none,TM=M,SS=M, 283
448386, AB037750, Hs 21061, KIAA1329 protein, PKD,BNR,TM=Y,SS=M, 282
427857, AL133017, Hs 288679 hypothetical protein FLJ22865, myosιn_head,IQ,zf-MYND,TM=M,SS=M, 282
407601, AC002300, Hs 37129, sodium channel, nonvoltage-gated 1, beta, ASC,TM=Y,SS=M, 282 459707, AA631362, Hs 120866, gb np86b01 s1 NCI CGAP.Thyl Homo εapienε, 7tm_1 none, 282 422699, BE410590, Hs 119257, emsl sequence (mammary tumor and squamou, SH3,HS1_rep,TM=M,SS=N, 282 438108, AI471795, Hs 287776, vanilloid rxeptor-related osmotically a ank.ionjrans TM=Y,SS=N 282 422241 , Y00062, Hs 170121 , protein tyrosine phosphatase, receptor t, kιnesιn,fn3,Y_phosphatase,TM=M,SS=N, 282 448595, AB014544, Hs 21572, KIAA0644 gene product, LRR LRRCT,TM=Y,SS=M, 281
423598, BE247600, Hs 377968, ESTs, 7tm_1,TM=Y,SS=M, 281 412970, AB026436, Hs 177534, dual specificity phosphatase 10, Rhodanese DSPc,, 281 414198, AW505308 Hs 75812, phosphoenolpyruvate carboxykiπase 2 (mil PEPCK , 281 436729, BE621807, Hs 351316, transmembrane 4 superfamily member 1, πoπe,TM=Y,SS=M, 2 81 432314 AA533447, Hs 285173, ESTs, Xlmk.none, 281
416207, NM 014745, Hs 79077, Homo sapiens, done MGC 2908, mRNA, comp, none TM=Y,SS=M, 280 446985, AL038704, Hs 156827, ESTs, Weakly similar to ALU1.HUMAN ALU S, SAM,SH3,HS1_rep, 280 428023, AL038843, Hs 374530, Homo sapienε cDNA FLJ23602 fiε, clone L, aa_permeases,pyπdoxaLdeC,bramodomam,PHD,MBD,AT_hook,DDT,PI3_PI4_kιnase,FAT,FATC,BolA,RUN,TM=M,SS=N, 280 432886, BE159028, Hs 279704, chramatin accessibility complex 1, none,TM=M,SS=N, 280
426006, R49031, Hs 22627, ESTε, pkinase BC, 279
414217, AI309298, Hs 279898, Homo sapiens cDNA FU23165 fis, clone L, none.NA.NA, 279 411165, NM.000169, Hs 69089, galxtosidase, alpha, Melibiase,, 279
450056, BE047394, Hs 502, ESTε, Weakly similar to S71512 hypotheti, ABC traπ ABC.membrane ig.MHCJI beta,SRP54,proteasome,ABC_membrane,ABC_tran, 278 424291, AL120051, Hs 144700, ephππ B1, Ephπn,TM=Y,SS=M, 278
421448, AF033850, Hs 104519, phospholipase D2, PH,PLDc,PX,TM=M,SS=N, 278 410226, AI831958, Hs 61053, hypothetical protein, SH3,TPR,TM=M,SS=N, 278 433535, AF111106, Hs 3382, protein phosphatase 4, regulatory subuni, HEAT,TM=M,SS=N, 278 442503, AF147078, Hs 375031, p53-responsιve gene 5, K_tetra,ιon_trans,none, 277 413900, AW409747, Hs 75612, stress-induced phosphoprotein 1 (Hsp70/H, TPR,PDZ,WW,Guany!ate_km,TM=M,SS=N, 277
454294, AB000734, Hs 50640, JAK binding protein, SH2,TM=M,SS=N, 277 440188, AK001812, Hs 7036, N Acetylglucosamme kinase, ROK,TM=M,SS=N, 277 449539, W80363, Hs 58446, ESTs, pkmase,Furιn-lιke,Rxep_L_domaιπ,none, 276 422667, H25642, Hs 132821, ESTs, FMO-lιke,FMO-lιke 276 415012, NM.004383, Hs 77793, c-src tyrosine kinase, SH2,SH3,pkιnase,TM=M,SS=N, 276
402316, , , NM.013447 Homo sapiens egf-iike module c, 7tm_2,GPS,TM=M,SS=M, 275 425465, L18964, Hs 1904, protein kinase C, iota, pkιnase,DAG_PE-bιnd,pkιnase_C,OPR,TM=M,SS=N, 275 447250, AI878909, Hs 17883, protein phosphatase 1G (formerfy 2C), ma, PP2C,TM=M,SS=N, 275 438629, AI187380, Hs 257170, ESTs, Weakly similar to T12515 hypotheti, TNFR_c6,none, 275 451144, AW956103, Hs 61712, pyruvate dehydrogenase kinase, isoenzyme, HATPase.c.none, 274
408543, N78098, Hs 44289, ESTs, none,TM=M,SS=N, 274 429345, R11141, Hs 199695, hypothetical protein, K etra.SAM, 274 407722, BE252241, Hs 38041, pyπdoxal (pyπdoxme, vitamin B6) kmas, pfkB,TM=M,SS=N, 273 420602, AF060877, Hs 99236, regulator of G protein signalling 20, RGS,TM=M,SS=N, 273 407217, AA477136, Hs 105584, πbosomal protein S6 kinase, 90kD, polyp, pkιnase,pkmase_C,TM=M,SS=N, 273
414135, NM.004419, Hs 2128, dual specificity phosphatase 5, Rhodanese,DSPc,Y_phosphatase,TM=M,SS=N 273 410590, BE615216, Hs 64746, chloπde intracellular channel 3, none,TM=M,SS=N 273 411125, AA151647, Hs 68877, cytochrome b-245, alpha polypeptide, none,TM=Y,SS=M, 273 438022, AW517524, Hs 135201, NOD2 protein, LRR.CARD.GTP CDC,Vιral_helιcase1,TM=M,SS=N, 272 420929, AI694143, Hs 326248, programmed cell death 4, MA3,TM=M,SS=N, 272
421155, H87879, Hs 102267, lysyl oxidase, Lysyl_oxιdase,Aldose_epιm,Epιmerase„ 272 448564, AL044962, Hs 21453, iπositol 1,4,5-tπsphosphate 3-kιnase C, IPK„ 271 449961, AW265634, Hs 133100, ESTs, pkinase.Fuππ lιke,Rxep_L_domaιn,πone, 271 444633, AF111713, Hs 12284, junotional adheεion molxule 1, ιg,TM=Y,SS=M, 271 412259, AI560292, Hs 279809, protein phosphatase 2 (formeriy 2A), reg, WD40,TM=M,SS=N, 271
419569, AI971651, Hs 91143, jagged 1 (Alagille syndrome), DSL,EGF,lamιnιn_EGF,vwc,metalthιo,TM=M,SS=M, 271 452401, NM_007115, Hs 29352, tumor nxrosis fxtor, alpha-induced pro, Xlmk.CUB,, 271 458190, BE561793, Hs 21446, KIAA1716 protein, ASC,Galxtosyl_T,none, 270 432126, AA865239, Hs 37196, ESTs, 7tm_1 ,TM=Y,SS=M, 270 422616, BE300330, Hs 118725, selenophosphate synthetase 2, AIRS,AIRS_C,TM=M,SS=N, 270
424717, H03754, Hs 152213, wmgless-type MMTV integration site fami, wntnone, 270 414108, AI267592, Hs 75761, SFRS protein kinase 1, ank,PH,Oxysteral_BP,pkιnase,TM=M,SS=N, 270 446272, BE268912, Hs 14601, hematopoietic cell-specific Lyn subεtrat, SH3,HS1_rep,TM=M,SS=N, 270 416084, L16991, Hs 79006, deoxythymidylate kmase (thymidylate km, none.none, 269 427157, U51166, Hs 173824, thymme-DNA glycosylase, UDG,TM=M,SS=N, 269
404891, , , Target Exon, none.none, 269
432581, AU076465, Hs 278441, KIAA0015 gene product, PP2C,TM=M,SS=N, 269 424321, W74048, Hs 1765, lymph∞yte-spxific protein tyrosine km, SH2,SH3,pkιnase,TM=M,SS=N, 268 425308, M97639, Hs 155585, rxeptor tyrosine kinase like orphan r , ιg,kπngle,pkιnase,Fz,TM=Y,SS=M, 268 414443, AU077268, Hε 76144, platelet-deπved growth fxtor rxeptor,, ιg,pkιnase,TM=Y,SS=N, 268
427274, NM.005211, Hs 174142, colony stimulating fxtor 1 rxeptor, to, ιg,pkιnase,TM=Y,SS=M, 268 436856, AI469355, Hs 127310, ESTs, pkιnase,rrm,TM=M,SS=N, 268 437429, H79981, Hs 5613, Homo sapiens mRNA, cDNA DKFZp564E2222 (f, SH2,SH3,BTB, 267 450690, AA296696, Hs 333418, FXYD domain-containing ion transport reg, ATP1G1_PLM_MAT8,TM=Y,SS=M, 267 452069, AB028949, Hs 183994, KIAA1026 protein, Metallophos,TM=M,SS=N, 267
445330, R52656, Hs 21691, ESTs, 7tm 1,πone, 267
452698, NM_001295, Hs 301921, chemokine (C-C motif) rxeptor 1, 7tm_1,TM=Y,SS=M, 267 419754, H52299, Hs 308467, Homo sapiens mRNA, cDNA DKFZp586l0523 (f, none,TM=M,SS=N, 267 434237, AF119908, Hs 235516, hypothetical protein PR02955, none,, 267 445826, BE313754, Hs 13350, Homo sapiens mRNA, cDNA DKFZp586D0918 (f, ιg,tsp_1,ZU5,Nud∞sιde_tran, 266
446696, AF279265, Hs 298476, solute earner family 26, member 6, SulfateJransp.STAS xaπ_ur_permease,TM=Y,SS=N, 266 439750 AL359053, Hs 57664, Homo sapiens mRNA full length insert cDN, IMPDH_C,IMPDH_N,CBS,ιπtegnn_B,Rιcm_B_tectιn 266 413745, AW247252, Hs 75514, nucleoside phosphorylase, Mtap.PNP,, 266 429083, Y09397, Hs 227817, BCL2-related protein A1, Bd-2,TM=M,SS=N, 266 449523, NM.000579, Hs 54443, chemokine (C-C motif) rxeptor 5, 7tm_1 ,TM=Y,SS=M, 266
449030, AI365582, Hs 57100, Homo sapiens mRNA for FLJ00016 protein, , transmembrane4,TM=Y,SS=M, 266
434979, AI953054, Hs 89643, traπsketolase (Wemicke Korsakoff syndro, ASC,transketolase,transkeLpyr,transketolase_C pkinase, 266
406137, , , NM_000179* Homo εapiens mutS (E coli) h, MutS.C PWWP,MutS_N,TM=M,SS=N, 266 412935, BE267045, Hs 75064, tubul specific chaperone c, none,, 266 408633, AW963372, Hs 222088, PRO2000 protein, bromodomaιn,AAA,Sιgma54_actιvat„ 266 412817, AL037159, Hs 74619, proteasome (prosome, macropam) 26S subu, PC_rep,TM=M,SS=N, 265 452682, AA456193, Hs 374574, progesterone membrane binding protein, homeobox none, 265 401752, , , RAN binding protein 3, SH2,STAT,STAT_bιnd,STAT_prot loπJrans.PAC.PAS Orexiπ, 265
450747, AI064821, Hs 129953, ESTs, Highly similar to 1818357A EWS gen rrm zf-RanBP,GAS2, 265 425776, U25128, Hs 159499, parathyroid hormone receptor 2, 7tm_2,HRM TM=Y,SS=M, 264 452701, NM 005110, Hs 30332, glutamine fructose 6 phosphate transamiπ, GATase 2,SIS,TM=M SS=N, 264 433933, AI754389, Hs 355397, Homo sapiens clone TCCCI A00164 mRNA sequ, none.NA.NA 264 421677, H64092, Hs 38282, ESTs, A1pp,Armadιllo_seg,IBB, 264
436469, AK001455, Hs 5198, Down syndrome critical region gene 2 none,, 264 423198, M81933, Hs 1634, cell division cycle 25A, Rhodanese.none, 264 435905, AW997484, Hs 5003, KIAA0456 protein, SH3,RhoGAP,FCH,TM=M,SS=N, 264
437712, X04588, Hs 85844, neurotrophic tyrosine kinase, receptor, , Tropomyosm,pkιnase,LRR,LRRCT,Hydantomase B,Hydantoιnase_A,TM=M,SS=N, 263 458946, AA009716, Hs 42311, ESTs, none,DSPc,Y_phosphatase, 263
447217, BE465754, Hs 17778, neuropilm 2, CUB,MAM,F5_F8_type_C,TM=M,SS=M, 263 445462, AA378776, Hs 288649, hypothetical protein MGC3077, none,, 263 425075, AA506324, Hs 1852, acid phosphatase, prostate acid.phosphat TM=Y,SS=M, 263 405588, , , NM.000299* Homo sapiens plakophilin 1 (e, Armadιllo_seg,TM=M,SS=N, 263 438330, AW450572 Hs 257316, ESTs, pkιnase,zf-C4,ERM,CNH,none, 263 448243, AW369771, Hs 367688, integnn, beta 8, integnn B.none, 263
452012, AA307703, Hε 279766, kinesm family member 4A, kmesm,DNA_topoιεolV,K-box,TM=M,SS=N, 2 63 412182, AA205588, Hs 73737, Splicing factor, arginiπe/seππe-πch, 4, rrm,hormone_rec zf-C4,εugar tr„ 263 423887, AL080207, Hε 134585, DKFZP434G232 protein, ABC tran,TM=Y,SS=N, 263 417497, AW402482, Hε 82212, CD53 antigen, transmembraπe4,TM=Y,SS=M, 262
413407, AI356293, Hs 75339, inositol polyphosphate phosphatase like , SH2,SAM,Exo_endo_phos„ 262 414998, NM.002543, Hs 77729, oxidised low density lipoprotein (Ixtm, lxtιπ_c,TM=Y,SS=M, 262 417880, BE241595, Hs 82848, selectm L (lymphocyte adhesion molecule, EGF,lxtιn_c sushι,TM=M,SS=M, 262 429922, Z97630, Hs 226117, H1 histone family, member 0, lιnker_hιstone,TM=M,SS=N, 262 401812, , , sorting nexm 14, AAA.NB ARC APS_kιnase,cdc48_N,cdc48_2,none, 261 417886 AA214584 , ESTs, SPRY,7tm_3 ANF.receptor.none, 261 457670, AF119666, Hs 23449, insulin receptor tyrosine kinase εubstra, SH3,TM=M,SS=N, 261 428512, AI018187, Hs 375624, Human DNA sequence from clone RP11-243J1, none,, 261 426746, J03626, Hs 2057, undine monophosphate synthetase (orotat Pπbosyltran.OMPdxase TM=M,SS=N, 261 454042, H22570, Hs 47860, hypothetical protein FLJ20093, ιg,pkιnase,LRR LRRNT.LRRCT.none, 261
421077, AK000061, Hs 101590, hypothetical protein, ank,pkιnase,death,SPRY,SAP,Rιbosomal L24e,SRP54,dDENN,DENN,uDENN,TM=M SS=N, 260 420162, BE378432, Hs 95577, cyclm-dependent kinase 4, pkinase,TM=M,SS=N, 260
416661, AA634543, Hs 79440, IGF-II mRNA-biπding protein 3, KH-domaιn,rrm,TM=M,SS=N, 260
417821, BE245149, Hs 82643, protein tyrosine kinaεe 9, cofilιn_ADF„ 260 411133, AW819204, , gb CM1-ST0283-071299 061-h03 ST0283 Homo, ANF.receptor.none, 260
405602, , , Target Exon, pkinase,, 260
400440, X83957, Hs 83870, nebulm, SH3,Nebulιn„ 2 60
424848, AI263231, Hs 327090, EST, SH3,PDZ,Guanylate_kιn,none, 259
432268, BE311856, Hs 274230, 3'-phosphoadenosιne 5'-phosphosulfate sy, APS_kιnase,ATP-sulfurylase,TM=M SS=N, 259 452690, AI536070, Hs 15085, ESTs, pou,homeobox,lιg_chaπ,ANF_receptor, 259
422753, AI928995, Hs 1575, small nuclear nbonucleoprotein D3 polyp, Sm , 259
428028, U52112, Hs 182018, ιnterleukιn-1 rxeptor-asεxiated kinase, death,pkιnase,TM=M,SS=N, 258
433573, AF234887, Hs 57652, cadhenn, EGF LAG seven-pass G-type rxe, 7tm_2,EGF,cadherm,lamιπιn_EGF,lamιnιn_G,Trypan_glycop,GPS,HRM,TM=Y,SS=M, 258
422785, AI824114, Hs 289088, heat εhxk 90kD protein 1 , alpha zf C2H2,πoπe, 258 418685, U76376, Hs 87247, harakiπ, BCL2-ιπteractιπg protein (cont, none,TM=M,SS=M, 258
452329, N36626, Hs 29106, mitogen-xtivated protein kinase phospha, DSPc,TM=M SS=N, 258
428405, Y00762, Hs 2266, cholmergic rxeptor, nicotinic, alpha p, Neur chan LBD.Neur chan_memb,TM=Y,SS=M, 258
421251, Z28913, Hs 102948, enigma (UM domain protein), LIM.PDZ,, 257
407245, X90568, Hs 172004, titin, fn3,ιg,SGXXSG,pkιnase,TM=M,SS=N, 257 422309, U79745, Hs 114924, solute camerfamily 16 (monxarboxylic, sugar_tr,TM=Y,SS=M, 257
401751, , , RAN binding protein 3, Orexin,SH2,STAT,STAT_bind,STAT_prot,ion_trans,PAC,PAS,none, 257
447887, AA114050, Hs 211610, caspaεe 8, apoptoεiε-related cysteine pπ ICE_p10,ICE_p20,DED,TM=M,SS=N, 257
422282, AF019225, Hs 114309, apolipopratem L MotA_ExbB,TM=Y,SS=M, 2 57
439863, BE547830, Hs 375208, paired immunoglobulin-like rxeptor beta, lιpoxygenase,PLAT,lιpoxygenase,PLAT, 257 425743, BE396495, Hs 159428, BCL2-ass∞ιated X protein, Bcl-2,TM=Y,SS=N, 257
401218, , , eukaryotic translation elongation fxtor, ιoπ_trans,TM=Y SS=N, 257
412773, H15785, Hs 74573, similar to vxcmia virus Hindlll K4L OR, PLDc,TM=M,SS=N, 257
444743, AA045648, Hs 301957, nudix (nucleoside diphosphate linked moi, NUDIX,sxY,E1_dehydrog,transkeLpynTM=Y,SS=M, 256
429782, NM.005754, Hs 220689, Ras-GTPase-xtivating protein SH3-domaιn, rrm,NTF2,TM=M,SS=N, 2 56 442994, AI026718, Hs 16954, ESTs, ank,pkmase,death,Rιbosomal_S14, 256
456602, AA411607, Hs 118964, ESTs, Weakly similar to KIAA1150 protein, none.pkinase, 256
422846, BE513934, Hs 1583, neutraphil cytosolic fxtor 1 (47kD, chr, SH3,PX,TM=M,SS=N, 256
441699, AW511126, Hε 127572, ESTs, noπe.Aa trans, 256
447912, AW576549, Hs 165728, ESTε, Weakly εimilar to I38022 hypotheti, none,GSHPx,ABC_tran, 256 442945, AI024849, Hε 131853, ESTs, pkmase.none, 256
453199, AI336266, Hs 32353, mitogen-xtivated protein kinase kinase , pkιnase,TM=M,SS=N, 256
451477, AI798425, Hs 42710, ESTs, SH3,none, 2 56
415091, AL044872, Hs 77910, 3-hydraxy-3-methyIglutaryl-Coenzyme A sy, HMG CoA.synt,, 2 55
413529, U11874, Hs 846, interleukin 8 rxeptor, beta, 7tm_1,TM=Y,SS=N, 255 425345, AU077297, Hs 155894, protein tyrosine phosphatase, non recept, Y_phosphatase,DSPc,TM=M,SS=M, 255
401321, , , rxeptor tyrosine kmase-like orphan rec, none,TM=M,SS=N, 255
446999, AA151520, Hs 351416, hypothetical protein MGC4485, none.none, 255
401057, , , eukaryotic translation elongation factor, lon.trans IQ,TM=Y,SS=N, 255
414509, AW161311, Hs 76294, CD63 antigen (melanoma 1 antigen), transmembrane4,TM=Y,SS=M, 255 408204, AA454501, Hs 43666, protein tyrosine phosphatase type IVA, m Y_phosphatase,TM=M,SS=N, 254
424539, L02911, Hs 150402, Activin A receptor, type I (ACVR1) (ALK, pkinase Actιvιn_recp,TM=M,SS=M, 254
459060, H89244, Hs 303627 heterogeneous nuclear nbonucteoprolem , rrm,pkιnase,TM=M,SS=N, 254
450167, AA446404, Hs 24563, NTF2-related export protein 1, NTF2,TM=M SS=N, 254 425966, NM.001761 Hs 1973 cyclin F, cyclιn,F-box,cyclm_C,TM=M,SS=N, 254 446566, H95741, Hs 17914, membrane-spanning 4-domams, subfamily A, none,TM=Y,SS=M, 254 412834, R77123, Hs 79881, Homo sapiens cDNA FU23006fis, clone L, 7tm_1,none, 2 54 457255, AL133011 , Hs 253920, Homo sapiens mRNA, cDNA DKFZp434P201 (fr, none.none, 2 54 431341, AA307211 Hs 251531, proteasome (prosome macropain) subunit , proteasome,TM=M SS=N, 253
417331, AW411297 Hs 81972, SHC (Src homology 2 domain containing) t, SH2,PID,zf-C2H2,SCAN,AMP bιndιng,KRAB,TM=M,SS=N, 253 414570, Y00285, Hs 76473, insulin-like growth factor 2 rxeptor, fn2,CIMR TM=M,SS=M, 253 444838, AV651680 Hs 208558, ESTs, mtegπn.A FG-GAP,none, 253
422609, Z46023, Hs 118721, sialidaεe 1 (lysosomal sialidase), BNR,SH2,SH3,pkιnase,TM=Y,SS=M, 253 450296, AL041949, Hs 24756, hepatocyte growth factor-regulated tyros, none.none, 253
400702, , , Target Exon, lιg_chaπ,SBP_bx_3,ANF_receptoπTM=Y,SS=M, 253 432336, NM_002759, Hs 274382, protein kinase, interferon inducible dou, dsrm,pkιnase,TM=M,SS=N, 253 442643, U82756, Hs 374973, PRP4/STK WD splicing fxtor; WD40„ 252 452060, W26980, Hs 349089, ATP-binding cassette, sub-family F (GCN2, ABC_tran,IRK,SWIB, 2 52 443951, F13272, Hε 356835, ferπtm, light polypeptide, PMP22_Claudιn,none, 252
428975, NM_004672, Hs 194694, mitogen-activated protein kinase kmase , pkinase,, 252 407608, AI928218, Hs 380063, ATPase, Na? transporting, beta 3 polypep, none.none, 251 414482, S57498, Hs 76252, endothelin receptor type A, 7tm_1,TM=Y,SS=M, 251 410293, AK000047, Hs 61960, hypothetical protein, K_tetra,TM=M,SS=N 251 429663, M68874, Hs 211587, phospholipaεe A2, group IVA (cytosolic, , C2,PLA2_B,TM=M,SS=N, 251
425424, NM.004854, Hs 157189, ELKL motif kinase, pkιnase,UBA,KA1,TM=M,SS=N, 251 457013, AA037145, Hs 172865, cleavage stimulation factor, 3' pre RNA,, WD40,TM=M,SS=N, 251 439221, AA737106, Hs 32250, ESTs, Moderately similar to I78885 serin, adh_short,Bcl-2,BH4,none, 251 405429, , , Target Exon, Y phosphatase.none, 251 443466, BE243123, Hs 321045, IKK-related kinase epsilon, inducible Ik, pkιnase,RI01,TM=M,SS=N, 251
418478, U38945, Hs 1174, cyclm-dependent kmase inhibitor 2A (me, ank,, 250 408056, AA312329, Hs 42331, ephππ-A4, Ephπn,TM=M,SS=M, 2 50 414419, F06829, Hs 76090, tumor necrosiε factor, alpha-induced pro, K_tetra,TM=M,SS=N, 250 405369, , , NM.005569* Homo sapiens UM domain kmas, pkιnase,LIM,PDZ„ 250 418216, AA662240 Hs 283099, AF15q14 protein, Hemagglutιnιn,squaεh,TM=Y,SS=N, 250
404321, , , C7001741* gι|2499629|sp|Q63932|MPK2_MOUS, none.none, 250 430900, U91939, Hs 248123, G protein coupled receptor 25, 7tm 1,TM=Y,SS=M, 249 440861, BE244115 Hs 7482, KIAA0682 gene product, πτn,Guanylate_kιn,TM=M,SS=N, 249 415801, R24219, Hs 278443, Fc fragmentof IgG low affinity lib re, ιg,TM=Y,SS=N, 249 418741, H83265, Hs 8881, ESTs, Weakly similarto S41044 chromosom, pkιnase,Actιvιn_recp,pkmase Actιvιn_recp, 249
417034, NM.006183, Hs 80962, neuroteπsin, none,, 249 400303, AA242758, Hs 79136, UV-1 protein, estrogen regulated, none.none, 249 408805, H69912, Hs 48269, vxcmia related kinase 1, pkιnase,TM=M,SS=N, 249 418255, AW135405, Hs 37251, ESTs, pkmase.πone, 249 424905, NM.002497, Hs 153704, NIMA (never in mitosis gene a) related k, pkιπase,TM=M,SS=N, 244
417791, AW965339, Hs 44269, ESTs, none,fer2,FAD_bιndιng_5,Ald_Xan_dh_C,fer2_2,Ald_Xan_dh_C2,CO_deh_flav_C, 244
453941, U38817, Hs 36820, Bloom syndrome, DEAD.helicase C,HRDC,TM=M,SS=N, 241
417849, AW291587, Hs 82733, nidogen 2, EGF,ldl_recepLb,thyragtobulιn_1,TM=M,SS=M, 239
408908, BE296227, Hε 250822, εenne/threonine kinase 15, pkinase,, 2 32 428513, BE220806, Hs 184697, plexin C1, PSI.none, 231
426761, AI015709, Hs 172089, PORIMIN Pro-oπcosis rxeptor inducing me, πone,TM=Y,SS=M, 231
427585, D31152, Hs 179729, collagen, type X, alpha 1 (Schmid metaph, C1q,Collagen„ 228
412723, AA648459, Hs 335951, hypothetical protein AF301222, none,TM=M,SS=N, 228
452461, N78223, Hs 108106, transcnption fxtor; zf-C3HC4,ubιquιtιn,PHD,YDG_SRA,TM=M,SS=N, 226 429547, AW009166, Hs 99376, FGENESH predicted novel secreted protein, none.none, 2 15
429486, AF155827, Hs 203963, hypothetical protein FU10339, SNF2_N,helιcase C,TM=M,SS=N, 2 15
401486, , , C4000647* gι|4758508|ref|NP_004253 1| ai, none,TM=Y,SS=M, 2 15
416209, AA236776, Hs 79078, MAD2 (mitotic arrest deficient, yeast, h, HORMA TM=M,SS=N, 2 14
424399, AI905687, Hs 348419, AI905687 IL-BT095-190199-019 BT095 Homo , πone,TM=M,SS=M, 2 14 423761, NM.006194, Hs 132576, paired box gene 9, PAX,TM=M,SS=N, 213
439670, AF088076, Hε 59507, ESTε, Weakly similar to AC0048583 U1 sm, none.none, 213
439318, AW837046, Hs 6527, G protein-coupled rxeptor 56, 7tm_2,CytC asm,GPS,TM=Y,SS=M, 203
445019, AI205540, Hs 281295, ESTs, none.none, 200
443211, AI128388, Hs 143655, ESTs, none.none, 1 98 449448, D60730, Hs 57471, ESTs, none.none, 1 92
435243, AW292886, Hs 348932, hypothetical protein dJ4340143, IRF.noπe, 1 85
406360, , , Target Exon, WD40,TM=M,SS=N, 1 84
411388, X72925, Hs 69752, deεmxollm 1, cadheππ,TM=Y,SS=N, 1 84
453102, NM.007197, Hs 31664, fπzzled (Drosophila) homolog 10, Fz,Fπzzied,7tm_2,TM=Y,SS=M, 1 79 419183, U60669, Hs 89663, cyt hrame P450, subfamily XXIV (vitamin, p450„ 1 78
420344, BE463721, Hs 97101, putative G protein-coupled receptoπ Methyltransf 5,TM=Y,SS=M, 1 77
432842, AW674093, Hs 334822, hypothetical protein MGC4485, Rιboεomal_L4,TM=M,SS=N, 1 76
419743, AW408762, Hε 5957, Homo sapiens clone 24416 mRNA sequence, none.none, 1 73
426427, M86699, Hs 169840, TTK protein kinase, pkinaεe,, 1 62 437915, AI637993, Hε 202312, Homo εapienε done N11 NTera2D1 teratoca, none.none, 1 58
433336, AF017986, Hε 31386, sxreted fnzzled-related protein 2 (stπ Fz.NTR,, 1 50
434377, AW137148, Hs 306593, intron of penostin (OSF-2os), Fasciclm.none, 1 47
451592, AI805416, Hs 213897, ESTs, none.none, 1 47
404927, , , Target Exon, Galactosyl_T,TM=M,SS=Y, 1 28 421552, AF026692 Hs 105700, sxreted fnzzled-related protein 4, Fz,NTR„ 1 27
427335, AA448542, Hs 278444, G antigen 7B, none,, 1 25
431808, M30703, Hs 270833, amphiregulm (schwannoma-deπved growth , EGF,TM=Y,SS=M, 1 24
447993, AW139525, Hs 170362, ESTs, none.none, 1 21
428182, BE386042, Hs 293317, ESTs, Weakly similar to GGC1.HUMAN G ANT, none,TM=M,SS=N, 1 18 453637, NM.002589, Hs 34073, BH-protocadhenn (brain heart), cadheπn,TM=Y,SS=M, 1 14
438274, AI918906, Hs 55080, ESTs, PAX none, 1 14
453966, BE148734, Hs 63325, transmembrane protease, senne 4, trypsιn,ldl_rxept_a none, 1 10
413268, AL039079, Hs 75256 regulator of G protein signalling 1, RGS,TM=M,SS=N, 1 07 429921, AA526911, Hs 82772, collagen, type XI, alpha 1, Collagen,COLFI,TSPN,iamιπιn_G,CorA„ 1 00 452795, AW392555 Hs 18878, hypothetical protein FU21620, 20G-Fell_Oxy,TM=M,SS=N, 1 00
TABLE 25B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession numbers Pkey CAT Number Accession
406685 0 0 M18728
418869 12789 14 AA229762 AA230035
425802 8884 3 AA122298 AA360788
417886 1031334 1 AA210987 D57294 AA214584AA207006 D56572
411133 1070995 1 AW819203 AW819204 AW819197 AW819202 AW819211 BE158469 AW819221 BE158473 AW819235 AW819207 AW819220 AW819208 AW819238
AW819198AW819234
TABLE 25C
Pkey Unique number corresponding to an Eoε probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromoεome 22 " Dunham I et al , Nature (1999) 402489-495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
401781 7249190 Minus 83215-83435,83531-83656,83740 83901,8423
401780 7249190 Minus 28397-28617,28920-29045,29135-29296,2941
401760 9929699 Plus 83126 83250,85320-85540,94719-95287
402075 8117407 Plus 121907-122035,122804-122921,124019-12416
401747 9789672 Minus 118596-118816,119119-119244,119609-11976
404996 6007890 Plus 37999-38145,38652-38998,39727-39872,4055
402447 9796640 Plus 47605-47729,51696-51821 ,52070 52257,5330
405932 7767812 Minus 123525-123713
406467 9795551 Plus 182212-182958
402233 7690102 Plus 90281-91477
402558 9863760 Plus 19047-19145,21133-21293,33968-34069
405556 1552511 Plus 163497-163623,164715-164968,165369-16550
403112 8980973 Minus 113051-113195
402316 7527774 Minus 10751-10919,18817-19052,22131-22328
404891 7329392 Plus 84974-85125
406137 9166422 Minus 30487-31058
401752 9828651 Plus 144600-144794
405588 5002511 Pius 4618046366
401812 7407975 Minus 55084-55391
405602 4753260 Plus 44647-44778
401751 9828651 Plus 139165-139322
401218 9929301 Minus 40793-41031
401321 9863631 Minus 104278-104748
401057 8117645 Plus 158309-159238
400702 8118856 Minus 11457-11585,26311-26536,27902-28067,3204
405429 7321905 Minus 51577-51723
405369 2078469 Minus 34183-34357,35686-35751
404321 9665209 Minus 76594-77805
401486 7341763 Plus 32585-32756,36281-36540,40791-40933,4401
406360 9256107 Minus 7513-7673
404927 7342002 Plus 68690 69563
TABLE 26A 834 GENES UP-REGULATED IN EWING'S SARCOMA COMPARED TO NORMAL ADULT TISSUES
Table 26A lists about 834 genes up-regulated in Ewmg's sarcoma compared to normal adult tissueε These were selxted from 35403 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" kidney cancer to "average" normal adult tiεsues was greater than or equal to 1 5 The "average" kidney cancer level was set to the 75lh percentile amongst Ewing sarcomas The "average" normal adult tisεue level was set to the 85* percentile amongst non-malignant tisεues In order to remove gene-spxific bxkground levels of non-specific hybridization, the 7 5"' percentile value amongst non-malignant tissues was subtrxted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcesεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of Ewing sarcoma to normal tissue
Pkey ExAccn UniGenelD UniGene Title R1
101447 M21305 gb Human alpha satellite and satellite 3 384
115881 NM 005756 Hs 184942 G protein-coupled rxeptor 64 34 2
110278 AF061573 Hs 19492 protocadhenn 8 322
121362 AF050147 Hs 97932 chondromodulin I precursor 303
101104 AW862258 Hs 169266 neuropeptide Y rxeptor Y1 26 3 121792 AW969726 Hs 98381 ESTs Weakly similar to serine protease 244
121619 AA528339 Hs 178062 ESTs Weakly similar to phosphatidylseπ 234
104659 AW969769 Hs 105201 ESTs 202
106533 AL134708 Hs 145998 ESTs 169
124006 AI147155 Hs 270016 ESTs 150
110728 AA737106 Hs 32250 ESTs Moderately similar to I78885 seπn 148
105782 H09748 Hs 57987 B cell CLL/lymphoma 11B (zinc finger pro 146
102836 U94320 Hs 158330 neuropeptide Y receptor Y5 145
104691 U29690 Hs 37744 Homo sapiens beta 1 adrenergic receptor 137
121231 AA814948 Hs 96343 ESTs Weakly similar to ALUC.HUMAN mi 123
129526 S69681 Hs 177582 surfactant pulmonary associated protein 12 1
119791 AA554907 Hs 58291 ESTs 11 7
116301 AW969706 Hs 293332 ESTs 11 2
123308 C14187 Hs 103538 ESTs 109
127742 AW293496 Hs 180138 ESTs 108
131601 NM 007115 Hs 29352 tumor necrosis fxtor alpha induced pro 107
127489 AA650250 Hs 272076 ESTs 106
115909 AW872527 Hs 59761 ESTs Weakly similar to DAP1_HUMAN DEATH 106
101063 D54745 Hs 80247 cholxystokinin 10 6
134570 U66615 Hs 172280 SWI/SNF related matrix assxiated acti 105
100299 D49493 Hs 2171 growth differentiation factor 10 10 1
127987 AI022103 Hs 124511 ESTs 101
131313 R96290 Hs 336629 πbosomal protein L44 92
126799 AW753865 Hs 74376 olfxtomedin related ER Ixalized protei 85
125847 AW161885 Hs 249034 ESTs 70
100380 D82343 Hs 18551 neurablastoma (nerve tissue) protein 69
114837 BE244930 Hs 166895 ESTε 66
123049 BE047680 Hs 211869 diekkopf (Xeπopuε laevis) homolog 2 66
129977 NM 000399 Hs 1395 early growth response 2 (Krox 20 (Drosop 65
127695 AA714731 Hs 291457 ESTε Weakly εimilar to heterogeneous r 65
125186 AA610620 Hs 181244 major histocompatibility complex class 64
118644 AA443241 Hs 336629 πbosomal protein L44 63
119717 AA918317 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger pro 63
101879 AA176374 Hs 243886 nuclear autoantigenic sperm protein (his 61
113003 AW292315 Hs 7215 ESTε 58
126645 AA316181 Hs 61635 six transmembrane epithelial antigen of 57
101050 AU077324 Hs 1832 neuropeptide Y 57
116790 AW161357 Hs 101174 microtubule assxiated protein tau 55
119082 AF252297 Hs 91546 cytochrome P450 retmoid metabolizing pr 5 1
132315 AF091086 Hs 44563 hypothetical protein 50
126098 M79088 gb EST01236 Subtrxted Hippocampus Stra 49
126077 M78772 Hs 210836 ESTε 47
126426 AA125984 gb zn27h06 r1 Stratagene neuroepithelium 46
131307 NM 000025 Hε 2549 adrenergic beta 3- rxeptor 45
123619 AA602964 gb no97c02 s1 NCI CGAP Pr2 Homo sapienε 44
128361 AW172570 Hε 130246 ESTε 43
127003 AW816515 Hs 173540 ATPase Class V type 10O 43
100020 42
125556 AB033064 Hs 334806 KIAA1238 protein 42
105316 AI671245 Hs 24835 hypothetical protein FU 14594 40
112268 W39609 Hs 22003 solute carrier family 6 (neurotransmitte 40
106516 AL137311 Hs 234074 Homo sapienε mRNA cDNA DKFZp761G02121 ( 39
128132 AA225632 gb nc08a07 r1 NCI_CGAP_Pr1 Homo εapiens 39
129012 R81936 Hs 336629 πbosomal protein L44 39
125447 AI582222 Hs 128686 ESTs 38
134676 W28051 Hs 87819 Homo sapienε clone MGC 2492 mRNA comp 36
119040 R02394 Hs 269436 ESTs Moderately similar to PC4259 fern 36
128391 AW188326 Hs 170652 ESTs 35
123829 AF251237 Hs 112208 XAGE-1 protein 34
123949 AA621665 Hs 208957 EST 34
126872 AW450979 gb UI H BI3-ala-a 120 UI s1 NCI_CGAP.Su 34
101266 L36645 Hs 73964 EphA4 33
121309 AA293834 Hs 97312 ESTs 33
130637 AA356764 Hs 17109 integral membrane protein 2A 32
125464 N71807 gb yz29d09 Soares.multiple.sclerosis. 32
135175 M91463 Hs 95958 εolute earner family 2 (facilitated glu 32
107599 AW664072 Hs 60136 ESTs 32
102681 Y08890 Hs 113503 karyopheπn (importin) beta 3 32
131688 AI935413 Hs 30692 p21 (CDKN1A) xtivated kinase 2 3 1
120147 AI917116 Hs 155376 hemoglobin beta 31
110343 AW136703 Hs 17268 ESTε 31
127664 AA806164 Hs 116502 ESTε 30
103076 NM.001034 Hs 75319 ribonucleotide reductase M2 polypeptide 30
126127 N95428 gb zb80d09 s1 Soares.senescenLfibroblas 30
125558 R59305 gb yh16c10 r1 Soares infant brain 1NIB H 30
100335 AW247529 Hs 6793 platelet activating fxtor xetylhydrola 29
133421 AF134160 Hs 7327 claudin 1 28
102581 AU077228 Hs 77256 enhancer of zeεte (Drosophila) homolog 2 28
113577 AI300699 Hs 278937 PRO0470 protein 28
118397 BE139479 Hs 161492 ESTs 28
115773 AW445044 Hs 38207 Human DNA sequence from clone RP4-530I15 28
128659 AW630087 Hs 103315 tπnucleotide repeat containing 1 28
127262 AA828125 gb od71a09 s1 NCI_CGAP_Ov2 Homo sapiens 28 106472 . AI207162 Hs 3815 stathm like protein RB3 27
125032 T74884 gb yc58d02 s1 Stratagene liver (937224) 27
127315 AF116622 gb Homo sapienε clone FLB4217 mRNA seque 27
126600 AA699949 Hs 191385 ESTs 27
120325 AA195651 Hs 104106 ESTs 27
127256 AI738610 Hs 267967 ESTs Moderately similar to ALU8_HUMAN 27
117357 N24829 gb yx98h12 s1 Soares melanocyte 2NbHM Ho 27
126735 M69113 Hs 226795 glutathione S transferase pi 27
102745 AW753865 Hs 74376 olfactomedm related ER localized protei 27
128040 AW500486 Hs 180610 splicing factor proline/glutamine rich ( 26
129706 AA443241 Hs 336629 ribosomal protein L44 26
107731 AA016086 Hs 272106 ESTs, Weakly similar to I38022 hypotheti 26
128283 AI076570 Hs 134053 ESTs 26
125165 W45350 gb zc81h08 s1 Pancreatic Islet Homo sapi 26
111148 AB020690 Hs 7782 paraneoplastic antigen MA2 26
105577 AW852257 Hs 171391 C-termmal binding protein 2 26
128301 U90552 Hs 284283 butyrophilin, subfamily 3, member A1 26
130262 D63216 Hs 153684 frizzled related protein 26
132967 AA316181 Hs 61635 six transmembrane epithelial antigen of 26
102479 NM 001991 Hs 194669 enhancer of zeste (Drosophila) homolog 1 26
128531 H03721 Hs 2953 ribosomal protein S15a 26
126165 AI741816 Hs 125897 ESTs 26
126086 H75681 gb yr77g01 r1 Soares fetal liver spleen 25
118967 AI668670 Hs 216756 ESTs 25
120830 A1568170 Hs 96886 ESTs 25
127229 AA316181 Hε 61635 six transmembrane epithelial antigen of 25
129428 AA256906 Hs 111364 ESTs, Weakly similar to ubiquitous TPR m 25
110151 H18835 Hs 31608 hypothetical protein FLJ20041 25
131381 M92642 Hs 26208 collagen, type XVI alpha 1 25
133761 AF041430 Hs 75922 brain protein 13 25
125590 R23858 Hs 143375 Homo sapiens clone IMAGE 3840937, mRNA 25
126693 C05723 gb C05723 Human pancreatic islet Homo sa 25
126021 AA775894 Hs 187516 ESTs 25
125905 AI678638 Hs 6456 chaperonin containing TCP1, subunit 2 (b 25
102507 U52154 Hs 193044 potassium inwardly rectifying channel, s 25
125743 H17151 gb ym37a05 r1 Soareε infant brain 1NIB H 25
130580 N32388 Hs 334370 uncharacteπzed hypothalamus protein HBE 25
113119 T47910 gb yb18b11 s1 Stratagene fetal spleen (9 24
123110 AA486256 Hs 193510 EST 24
113283 T66813 Hs 12947 EST 24
107711 W96141 Hs 220687 ESTε 24
128992 H04150 Hs 107708 ESTs 24
106111 AW875398 Hs 6451 PRO0659 protein 24
129948 AI537162 Hs 263988 ESTs 24
125728 AW954565 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger pro 24
116728 F13687 Hs 227976 EST 24
103100 NM 005574 Hs 184585 UM domain only 2 (rhombotm like 1) 24
124971 T23800 Hs 151001 hypothetical protein FLJ14728 24
131019 W28614 Hs 306155 choπonic somatomammotropin hormone 1 (p 24
128671 AI885045 Hs 211586 phosphoιnosιtιde-3-kιπase, regulatory s 24
111795 AI435437 Hs 24567 ESTs, Weakly similar to KBF3.HUMAN NUCL 24
119127 AA708035 Hs 12248 ESTs 24
117602 N35020 Hs 44685 C3HC4-lιke zinc finger protein 24
111898 R38944 Hs 183475 Homo sapienε clone 25061 mRNA εequence 24
131916 AA025976 Hε 34569 ESTε 24
130850 AB040922 Hε 20237 DKFZP566C134 protein 24
100571 L14561 Hs 78546 ATPase, Ca++ transporting, plasma membra 24
126722 N66148 Hs 11125 HSPC033 protein 24
123720 AA609734 Hs 112755 EST 24
113609 T93263 Hs 16875 ESTs, Weakly similar to S23650 retrovir 24
131136 AB033099 Hs 23413 KIAA1273 protein 24
129001 AA443323 Hs 107812 BPOZ protein 24
133529 W45623 Hs 74571 ADP πbosylation fxtor 1 24
107593 AI093688 Hs 60051 ESTs 24
123910 AA621262 Hs 179923 ESTs, Weakly similar to S65657 alpha-1 C- 24
128817 BE395776 Hs 168640 ankylosis, progressive (mouεe) homolog 24
103080 AU077231 Hs 82932 cyclin D1 (PRAD1 parathyroid adenomatos 24
128367 AW611791 Hs 150742 ESTs 24
123729 AL039779 Hs 278672 membrane component, chromosome 11, surfa 24
112342 AW410273 Hs 92614 longevity assurance (LAG1, S cerevisiae 23
114721 D61939 Hs 103822 ESTs 23
127768 AW085002 Hs 156187 ESTs 23
127706 AI174238 Hs 186982 ESTs 23
126029 AA704253 Hs 169359 ESTs 23
124250 AA350256 Hs 323875 EST, Weakly similar to 2109260A B cell 23
117265 AA451966 Hs 43005 RAB9 like protein 23
112501 AA972447 Hs 288833 Homo sapiens mRNA, cDNA DKFZp434K087 (fr 23
129079 AK000157 Hs 108502 hypothetical protein FLJ20150 23
127252 : AI049545 Hs 94 DnaJ (Hsp40) homolog subfamily A membe 23
129228 l U40714 Hs 239307 tyrosyl tRNA synthetase 23
114092 '. H81213 Hs 14825 ESTs Weakly similar to KIAA1503 protein 23
109252 I BE440157 Hs 85944 ESTs 23
12788S I AI147408 Hs 144941 ESTs 23 gb zv65f11 s1 Soares_total_fetus_Nb2HF8_ 2 3
128797 NM 002975 Hs 105927 stem cell growth fxtor, lymphxyte seer 23
132985 AL045579 Hs 62113 KIAA0717 protein 23
125174 W51835 Hs 231082 EST 23
125401 AI204637 Hs 337585 ESTs, Highly similar to KIAA0350 [H sapi 23
135278 AA399542 Hs 229671 EST, Moderately similar to PEPTIDYL-PROL 2 3
119155 R61715 Hs 310598 ESTs, Moderately similar to ALU1.HUMAN 23
123423 AA598484 gb ae38f04 s1 Gessler Wilms tumor Homo s 23
123258 AA490929 Hs 105274 ESTε Weakly similar to RMS1.HUMAN REGUL 2 3
128826 Z40313 Hs 106330 Homo sapiens clone IMAGE 23371 , mRNA seq 23
105014 AA121123 Hs 269267 ESTs, Weakly similar to AF161361 1 HSPC 2 3
101086 AA382524 Hs 250959 histatm 1 2 3
110679 AA004798 Hs 108311 ESTs, Weakly similar to T00351 hypotheti 23
126879 D90391 Hs 1265 branched chain keto acid dehydrogenase E 2 3
132317 BE262438 Hε 44592 beta-1,4 mannosyltransferase 2 3
124691 R05835 Hs 110153 ESTs 23
113474 R50752 Hs 23856 hypothetical protein MGC5297 23
103175 X69089 Hs 79227 myomesm (M protein) 2 (165kD) 2 2
129052 BE275031 Hs 158210 hypothetical protein MGC2555 22
129248 W04606 Hs 171637 hypothetical protein MGC2628 22
100780 BE561958 Hs 302063 immunoglobulin heavy constant mu 2 2
135416 BE281018 Hs 99969 fusion, denved from t(12,16) malignant 22
129928 AI338993 Hs 134535 ESTs 2 2
103319 X83492 Hs 82359 tumor necrosis factor receptor superfami 22
110256 H63947 Hs 237955 RAB7, member RAS oncogene family 22
120734 AA299948 gb EST12544 Uterus tumor I Homo sapiens 2 2
111777 AK001100 Hs 41690 desmxollin 3 22
128963 J03890 Hs 1074 surfactant, pulmonary-associated protein 22
108451 AA079195 gb zm92h12 s1 Stratagene ovanan cancer 2 2
134964 AI803516 Hs 272891 hippxalcin like protein 4 22
127248 AA364195 gb EST75015 Pineal gland II Homo sapiens 22
125761 R68351 gb yh99b03 r1 Soares placenta Nb2HP Homo 2 2
101358 M10058 Hs 12056 asialoglycoprotein receptor 1 22
101613 M24283 Hs 168383 intercellular adhesion molxule 1 (CD54) 22
107121 AB015427 Hs 250493 zinc finger protein 219 2 2
118751 N74210 Hs 50454 ESTs 22
128952 AL043463 Hs 6755 RaP2 interacting protein 8 22
126581 W73306 Hs 306668 Homo sapiens cDNA FLJ14089 fis, clone MA 22
127634 AA633469 Hs 193283 ESTs, Weakly similar to unnamed protein 22
130755 BE293520 Hε 18910 prostate cancer overexpressed gene 1 22
132867 AF226667 Hs 58553 CTP synthase II 22
126323 N77584 Hs 68644 Homo sapiens micrasomal signal peptidase 22
111790 AW769683 Hs 6734 ESTs, Weakly similar to S26650 DNA bmdi 22
125549 R20215 gb yg18b09 r1 Soares infant brain 1NIB H 22
128059 AA972446 Hs 145096 ESTs 2 2
132342 AW162758 Hs 45232 ESTs, Weakly similar to AUJ5_HUMAN ALU S 22
125722 H29796 Hs 269622 ESTs 2 2
106383 AA447453 Hs 27860 Homo sapiens mRNA, cDNA DKFZp586M0723 (f 22
127644 N88858 Hs 155101 ATP synthase, H+ transporting, mitochond 22
128179 AW293689 Hs 127116 ESTs 2 2
133461 NM 000762 Hs 334345 cytxhrome P450, subfamily HA (phenobar 22
126962 R12014 Hs 20976 ESTs 22
112369 AW966243 Hs 4243 hypothetical protein FLJ12650 22
133582 BE391579 Hs 75087 Fas-xtivated serme/threonine kinase 22
112276 R53442 Hs 26038 ESTε, Weakly similar to I38022 hypothet 2 2
108743 AI580150 Hs 71074 ESTs 22
133726 AI803188 Hs 252716 oxysterol-hmding protein-related protei 22
131263 AU077002 Hs 24950 regulator of G-protein signalling 5 2 2
109929 AA773187 Hε 294027 ESTs 22
129059 AW069534 Hs 279583 CGI-81 protein 2 2
110724 AW016783 Hs 30799 Homo sapiens cDNA FLJ13471 fis, clone PL 22
116962 H79677 gb yu76g10 s1 Soares fetal liver spleen 22
119232 AI655226 Hs 117659 ESTs, Weakly similar to T46481 hypotheti 22
106711 BE390125 Hs 143187 hypothetical protein 22
135191 X16866 Hs 301086 cytochrome P450, subfamily HD (debπεoq 2 2
125822 H03162 Hs 268768 ESTε 22
130215 BE301883 Hs 152707 glioblastoma amplified sequence 2 2
133363 AI866286 Hs 71962 ESTs, Weakly εimilar to B36298 proline r 2 2
126250 AL050391 Hs 321247 Homo sapiens mRNA, cDNA DKFZp586A181 (fr 22
103392 X94563 gb H sapienε dbi/xbp gene exon 1 & 2 22
129794 AF161399 Hs 23259 hypothetical protein FU13433 22
100253 D38024 Hε 157425 double hom∞box, 2 2 2
130743 AL049266 Hs 18724 Homo εapienε mRNA cDNA DKFZp564F093 (fr 22
125466 R08234 Hs 180461 ESTs 22
122682 AA984531 Hs 159293 ESTs 2 2
133347 BE257758 Hs 71475 acid cluster protein 33 22
104455 AL110261 Hs 157211 DKFZP586B0621 protein 2 2
116332 AA491208 Hs 62620 chromosome 6 open reading frame 1 2 2
131163 AA099524 Hs 23754 ESTs 22
109592 AH 98059 Hs 26370 ESTs 2 2
128721 AW403911 Hs 266175 phosphoprotein associated with GEMs 2 1
114046 BE018658 Hs 141003 Homo sapiens cDNA FU21691 fis, clone C 2 1
128434 AI190914 Hs 143880 ESTs 2 1 103163 AU077018 Hs 3235 keratin 4 21
112379 AK001713 Hs 17860 hypothetical protein FLJ10851 21
127507 AA249573 Hs 152618 ESTs, Moderately similar to ZN91_HUMAN Z 21
133097 W03512 Hs 6479 hypothetical protein MGC13272 21
126153 H85692 Hs40730 ESTs 21
122110 AH23000 Hs 301240 melanocortm 1 receptor (alpha melanocyt 21
100554 M95923 gb Human 12-lιpoxygenase mRNA, partial c 21
104799 AA029703 gb ze95h08 s1 Soares fetal_heart_NbHH19W 21
132664 AI740461 Hs 54542 ESTs 21
114620 AA642974 gb nr60h01 s1 NCI CGAP.Lym3 Homo sapiens 21
115348 AA281562 Hε 292100 ESTs 21
133231 AK000517 Hs6844 hypothetical protein FU20510 21
133160 N54968 Hs 66309 hypothetical protein MGC11061 21
124656 AW297702 Hs 102915 ESTs 21
133576 M19650 Hs 150741 2',3'-cyclιc nucleotide 3 phosphodieste 21
132676 N92589 Hs 261038 ESTs, Weakly similar to I38022 hypothet 21
126505 AA282881 Hs 190057 ESTs 21
118865 AA736405 Hs 54530 ESTs 21
134267 AI174596 Hs 196209 RAE1 (RNA export 1, S pombe) homolog 21
134104 L35253 Hs 79107 mitogen-activated protein kinase 14 21
133493 AW998046 Hs 194369 argmme glutamic acid dipeptide (RE) re 21
112853 T02843 gb FB11 H5 Fetal brain, Stratagene Homo s 21
117457 N29682 Hs44071 ESTs, Weakly similar to ALU5_HUMAN ALU 21
112246 R51321 Hs 25780 Homo sapiens cDNA FLJ 12252 fis, clone MA 21
134869 AL157518 Hs 90421 PR02463 protein 21
128869 AA768242 Hs 80618 hypothetical protein 21
129179 AW969025 Hs 109154 ESTε 21
104857 AI920902 Hs 19058 ESTs, Moderately similar to S65657 alpha 21
101651 AL037111 Hs 75641 galactose-1-phosphate uπdylyltransferaε 21
129726 H15474 Hs 132898 fatty acid desaturase 1 21
117186 H98988 Hs 42612 ESTs, Weakly similar to ALU1 HUMAN ALU S 21
126271 AI250773 Hs 270012 ESTs 21
116925 H73110 Hs 260603 ESTs, Moderately similar to A47582 B-ce 21
128468 T23625 Hs 150580 putative translation initiation factor 21
116031 AA452239 Hs 103329 KIAA0970 protein 21
130724 AK001507 Hs306084 Homo sapiens clone FLB6914 PR01821 mRNA, 21
121897 AA427419 Hs 229162 EST, Weakly similar to ZN91_HUMAN ZINC 21
123808 AA620552 gb ae58g11 s1 Stratagene lung carcinoma 21
122333 AA625872 Hs 98977 ESTs, Moderately similar to T34561 hypot 21
127841 AW136558 Hs 125246 ESTs 21
100023 21
113002 BE243513 Hε7212 hypothetical protein PP1044 21
111567 F12628 Hs 334786 hypothetical protein MGC16040 21
113697 T97183 Hs 17992 Homo εapieπs mRNA cDNA DKFZp434J1726 (f 21
128033 AI248705 Hs 149321 ESTs 21
105225 AA211777 gb zn57d02 s1 Stratagene muscle 937209 H 21
112370 AF052095 Hs 167344 Homo sapienε clone 23911 mRNA sequence 21
132786 BE083422 Hε 56851 hypothetical protein MGC2668 21
113226 AI821008 Hε 10697 ESTs 21
117997 N52090 Hs47420 EST 21
116986 H83935 Hs40535 ESTs 21
127002 AL353940 Hs 24979 hypothetical protein DKFZp761P1010 21
122591 AI188219 Hs99311 ESTε, Weakly similarto HSJ2.HUMAN DNAJ 21
107279 S57296 Hs 323910 v-erb-b2 avian erythroblastic leukemia 21
103898 AA248884 gb k3517 seq F Human fetal heart, Lambda 21
110312 BE256986 Hs 11896 hypothetical protein FLJ 12089 21
127447 AA386192 Hs 193482 Homo εapienε cDNA FLJ11903 fis, clone HE 21
128352 AW137413 Hs 169942 ESTs 21
113649 N94768 Hs 16400 ESTε, Weakly εimilar to KIAA1435 protein 20
128275 AI218235 Hs 131240 ESTε 20
125976 AA436760 gb zv67d11 r1 Soares total_fetus_Nb2HF8 20
120820 AA347417 Hs 96869 EST 20
134937 AI251449 Hs 171939 ESTε 20
129602 AI2821S3 Hs 198298 v-src avian sarcoma (Schmidt-Ruppm A-2) 20
129535 AA397972 Hs 169965 chimenπ (chimaenn) 1 20
106095 AF115402 Hs 11713 E74-lιke fxtor 5 (ets domain transcript 20
128538 R44214 Hs 101189 ESTs 20
105593 AA279341 Hs 174151 aldehyde oxidase 1 20
105788 AB009698 Hs 23965 solute camerfamily 22 (organic anion 20
128148 AA918175 Hs 126637 ESTs 20
125982 R98091 gb yr30e11 rl Soares fetal liver spleen 20
125746 AL137506 Hs 274256 hypothetical protein FLJ 23563 20
127835 AA748762 Hs 163113 ESTs, Weakly similarto 138022 hypotheti 20
100661 BE623001 Hs 132748 Homo sapiens ribosomal protein L39 mRNA, 20
124282 AA018408 Hs 110287 ESTs 20
126926 AA179472 Hs832 ESTs Highly similar to A41029 integnn 20
100221 D28383 gb Human mRNA for ATP εynthase B chain, 20
126053 H64450 gb yu62d01 r1 Weizmanπ Olfxtory Epithel 20
100944 L07518 Hs 159593 mucin 6, gastπc 20
125581 AI272848 Hs75309 eukaryotic translation elongation factor 20
128604 ; AI879099 Hs 102397 GIOT-3 for gonadotrop inducible transc 20
114615 ! AI124557 Hs 95456 ESTs 20
130453 I U80735 Hs 173854 PAX transcription xtivation domain inte 20 135060 AK001887 Hs 259842 protein kinase, AMP-activated, gamma 2 n 20
114419 AI248013 Hs 106532 ESTs, Weakly similar to I38588 reverse t 20
126283 N40359 Hs 271896 ESTs 20
112003 AW978731 Hs 301824 hypothetical protein PR01331 20
127391 AW380893 Hs 11039 hypothefical protein MGC2722 20
127717 F12209 Hs 173380 CK2 interacting protein 1 , HQ0024c prote 20
126893 AJ252060 Hs 26320 TRABID protein 20
106798 BE252749 Hs 20558 hypothetical protein FLJ20345 20
103760 AA642973 Hs 183842 ubiquitin B 20
118922 AW206193 Hs 91065 hypothetical protein DKFZp761 B2423 20
133195 AI434760 Hs 279949 KIAA1007 protein 20
133424 AA350994 Hs 20281 KIAA1700 20
133765 M62194 Hs75929 cadhenn 11 , type 2, OB-cadhenπ (ostxb 20
132347 BE271016 Hs 169850 ESTs, Weakly similar to T21554 hypotheti 20
125599 H13295 Hs 106135 ESTs 20
114459 AW445217 Hs 103362 ESTs 20
128478 AA708205 Hs 100343 ESTs 20
127271 H96820 gb yv99b03 r1 Soares melanocyte 2NbHM Ho 20
111122 N63753 Hε 16492 DKFZP564G2022 protein 20
130695 T97205 Hs 17998 ESTε, Weakly similar to 2109260A B cell 2 0
133571 BE515037 Hs 177556 melanoma antigen, family D, 1 20
119244 AW407564 Hs 275865 ribosomal protein S18 2 0
127603 AI016798 Hs 9925 hypothetical protein FLJ20772 20
113626 T94318 Hs 17359 ESTs, Moderately similar to RL44.HUMAN 6 20
128115 AI435590 Hs 130168 ESTs 20
117639 AA377165 Hs 44833 ESTs 2 0
127033 AF169301 Hs9098 sulfate transporter 1 20
112411 R43090 Hs 271510 ESTs, Moderately similar to ALU1_HUMAN A 20
114601 AA075566 gb zm88f06 s1 Stratagene ovanan cancer 20
127573 AA594196 Hs269464 ESTs, Weakly similar to S65657 alpha-1 C- 2 0
125500 AW952654 Hs 244624 ESTs 20
119416 T97186 gb ye50h09 s1 Soareε fetal liver εpleen 2 0
115467 AI366784 Hs 48820 TATA box binding protein (TBP)-assxιate 20
128902 AA036637 Hs 107052 ESTs 2 0
127684 AA668631 Hs 32556 KIAA0379 protein 20
126288 AW449560 Hs 89576 inner mitochondnal membrane peptidase 2 2 0
122059 AA431737 Hs 98749 EST, Moderately similar to T42671 hypoth 20
125486 AI023895 Hs 190587 ESTs 2 0
128895 AW467000 Hs 106985 ESTs 20
105301 AW352357 Hs7457 MAGE1 protein 20
125536 F08266 Hs 77948 ESTs, Weakly similar to ALULHUMAN ALU S 20
121387 AA405854 gb zu66g08 s1 Soares.testis.NHT Homo εap 20
134126 NM.003747 Hs 131814 taπkyraεe, TRF1-mterxtιng ankyπn rela 20
126860 BE242814 Hs 323494 ESTs, Weakly similar to T27544 zinc resi 20
102907 BE409861 Hs 202833 heme oxygeπase (dxyding) 1 20
127804 AA740634 Hs 292084 ESTs 20
130566 R85474 Hs 16073 ESTs 1 9
113782 AK001567 Hs 311002 Homo sapiens cDNA FLJ10705 fis, clone NT 1 9
124119 AA040123 Hs 248953 εolute earner family 27 (fatty xid tra 1 9
132490 NM 001290 Hs4980 UM domain binding 2 1 9
125494 AU077029 Hs 177543 antigen identified by monoclonal antibod 1 9
100237 D30715 Hs 306333 Human PAP (pancreatitiε-ass∞iated prot 1 9
127687 AW772383 Hs 300635 ESTs 1 9
103136 AF087917 Hs 247936 olfxtory rxeptor, family 1 , subfamily 1 9
125704 R55094 Hs 26239 Human DNA sequence from clone RP11438B2 1 9
126208 N22588 Hs288548 Homo sapiens cDNA FU12368 fis, clone MA 1 9
131902 AA180145 Hs 34348 Homo sapiens mRNA, cDNA DKFZp434P0235 (f 1 9
128660 AA011597 Hs 177398 ESTs 1 9
118049 N53145 gb yv55f09 s1 Soares fetal liver spleen 1 9
134624 AF035119 Hs 8700 deleted in liver cancer 1 1 9
127432 AW067708 Hs 170311 heterogeneous nuclear πbonuclxprotein 1 9
126414 AI363157 Hs 24756 hepatxyte growth fxtor-regulated tyros 1 9
120861 AA350394 Hs 96952 ESTs 1 9
124669 AI571594 Hs 102943 hypothetical protein MGC12916 1 9
126096 F08208 Hs 283844 similar to rat tπcarboxylate camer-li 1 9
103891 NM 007212 Hs 124186 nng finger protein 2 1 9
128727 AI223335 Hs 50651 Janus kinase 1 (a protein tyrosine kmas 1 9
126831 AI929107 Hs 79933 cyclin I 1 9
125360 AW898892 Hs 189741 ESTε 1 9
124276 H83465 gb ys91a11 s1 Soares retina N2b5HR Homo 1 9
126524 Z45455 Hs 182447 heterogeneous nuclear πbonucl∞pratein 1 9
126647 AK000283 Hs 270502 hypothetical protein FLJ20276 1 9
125957 H41694 gb yo06b06 r1 Soares adult brain N2b5HB5 1 9
121782 AW452957 Hε 334698 Homo sapiens, clone MGC 15203, mRNA com 1 9
124059 BE387335 Hs 283713 ESTs, Weakly similar to S64054 hypotheti 1 9
130945 U20582 Hs 2149 adm like protein 1 9
126348 T16243 Hs 6473 Homo sapiens cDNA FLJ13992 fiε, clone Y7 1 9
103558 BE616547 Hs 2785 keratin 17 1 9
126982 AA211419 gb zn55g05 s1 Stratagene muscle 937209 H 1 9
125613 AA765957 Hs 21077 KIAA0532 protein 1 9
129601 AB032964 Hs 115726 KIAA1138 protein 1 9
126007 H51097 Hs 143261 ESTs 1 9
123627 AA909619 Hs 112668 ESTε 1 9 111587 AI125867 Hs 20734 ESTs
135231 BE613615 Hs 74280 hypothetical protein FLJ22237
128897 AW979134 Hs 10700 hypothetical protein
109891 H04757 Hs 323176 ESTs
127704 AA679609 gb ag72c02 s1 Gessler Wilms tumor Homo s
129340 H75334 Hs 11050 F box only protein 9
126502 T10077 Hs 13453 hypothetical protein FLJ 14753
129619 AA209534 Hs 284243 tetraspan NET 6 protein
127136 R36277 Hs 7773 Homo εapiens ubiquitin conjugating enzym
110636 H72868 Hs 19110 ESTs
128862 BE250742 Hs 106673 eukaryotic translation initiation factor
104689 AA420450 Hs 292911 ESTs Highly similar to S60712 band 6 pr
130829 BE262530 Hs 2006 glutathione S transferase M3 (brain)
125768 AI557486 Hs 119122 ribosomal protein L13a
123613 AA609158 Hs 291166 EST
127506 T61039 Hs 252574 πbosomal protein L10a
123546 AA608817 Hs 112597 EST
126516 R95872 Hs 117572 chemokine binding protein 2
103973 AA305729 Hs 18272 ammo acid transporter system A1
127426 AA854756 Hs 124076 ESTs
112339 R56570 Hs 50547 ESTs
129101 NM 013403 Hs 108665 zmedin
109442 AW296134 Hs 86999 ESTs Weakly similar to S65657 alpha 1C-
118103 AA401733 Hs 184134 ESTε
125752 AW136622 Hs 206673 ESTε
102926 W28363 Hs 239752 nuclear rxeptor subfamily 2 group F m
133975 C18356 Hs 295944 tissue factor pathway inhibitor 2
134470 X54942 Hs 83758 CDC28 protein kmase 2
127329 AW160551 Hs 124021 soggy 1 gene
126659 T16245 gb NIB1005R Normalized infant brain Ben
127297 AW629485 Hs 140720 GSK 3 binding protein FRAT2
127640 AI557486 Hs 119122 nbosomal protein L13a
103409 NM 004454 Hs 43697 ets variant gene 5 (ets related molecule
127964 F06298 gb HSC13F081 normalized infant brain cDN
122365 AA813546 Hs 99034 GTP binding protein Rho7
128193 AJ224442 Hs 155020 putative methyltraπsferase
115173 BE612940 Hs 88252 ESTs
125532 AI734146 Hs 271800 ESTs Weakly similar to alternatively sp
126541 AJ271671 Hs 7854 zinc/iron regulated transporter like
127309 AI669765 Hs 133184 ESTs
129062 AA452970 Hs 155218 E1B 55kDa associated protein 5
126770 AI292320 Hs 81361 heterogeneous nuclear πbonucleoprotem
127775 AA128808 Hs 179902 tranεporter like protein
126994 AA455265 Hs 86686 ESTs Moderately similar to I54374 gene
130734 AW137091 Hs 18624 KIAA1052 protein
114461 AA531187 Hs 126705 ESTs
100842 U05597 gb Human aπion exchanger 3 cardiac isofo
127389 T65126 Hs 12743 carnitine O xtanoyltransferase
125394 BE178502 Hs 173772 ESTs Weakly similar to 178885 senne/th
107736 AA016239 Hs 60715 ESTε
125669 R51308 Hs 333256 ESTs Weakly similar to ALU8.HUMAN ALU
100370 D79989 Hs 184884 KIAA0167 gene product
113479 AI023133 Hs 10739 ESTs
105165 BE280787 Hs 16079 hypothetical protein FLJ10233
120602 AA808018 Hs 109302 ESTs
112399 R60920 Hs 296770 KIAA1719 protein
123474 AA599209 gb ag34b11 s1 Jia bone marrow stroma Hom
134212 AA654353 Hs 17719 EBP50 PDZ interxtor of 64 kD
104204 AK001691 Hs 57655 hypothetical protein FLJ10829
127464 AW971875 Hs 292071 ESTs
116715 AL117440 Hs 170263 tumor protein p53-bιndιng protein 1
115041 AA252457 Hs 86543 ESTs Moderately similar to T00256 hypot
132380 AW373665 Hs 46853 ESTs
120087 AF186780 Hs 79219 RalGDS like gene KIAA0959 protein
116356 AI371223 Hs 288671 Homo sapιenε cDNA FLJ11997fis ctone HE
125498 H10543 gb ym04c06 r1 Soares infant brain 1 NIB H
128846 AA730767 Hs 285753 SCG10 like protein
123869 AA620924 Hs 112923 EST
108889 AA135722 Hs 61481 ESTs
126528 Z24895 gb HSB67F122 STRATAGENE Human skeletal m
127629 AA293279 Hs 29173 hypothetical protein FU20515
130004 AA703684 Hs 245474 ESTs Moderately similar to ALU5_HUMAN A
130847 AI672483 Hs 20220 lipase protein
111620 R14853 Hs 307478 EST Weakly similar to 139058 hypotheti
131971 BE567100 Hs 154938 hypothetical protein MDS025
121360 AA405635 Hs 96854 ESTs Weakly similar to DYLX.HUMAN CYTOP
127705 AJ003322 gb AJ003322 Selected chromosome 21 cDNA
124687 AA833902 Hs 270745 ESTs
126698 AI221147 Hs 145088 ESTs Weakly similar to T15936 hypotheti
126730 AA442429 gb zv70g02 r1 Soares_total_fetus_Nb2HF8_
127916 AI239950 Hs 294111 ESTs Moderately similar to B34087 hypo
128408 A1183407 Hs 143704 EST
128440 AW090340 Hs 14337 Homo sapiens cDNA FLJ14407 fis clone HE 123783 AA610112 gb af19g05 si Soares_total_fetus_Nb2HF8_ 1 8
109152 AW380723 Hs 73451 ESTε, Weakly similar to S55024 nebulin, 1 8
107242 AB020672 Hs 175411 KIAA0865 protein 1 8
132804 AI805943 Hs 326067 hypothetical protein MGC5178 1 8
125387 AJ243669 Hs 8127 KIAA0144 gene product 1 8
121578 AA398791 Hs 178185 ESTs 1 8
132944 T96641 Hs 6127 Homo sapiens cDNA FLJ23020 fis, clone L 1 8
126295 AI281459 Hs 270114 ESTs 1 8
133335 BE251012 Hs 263812 nuclear distnbution gene C (A πidulaπs) 1 8
129879 AK001696 Hs 13109 Ran binding protein 11 1 7
125175 W52355 Hs 303030 EST 1 7
126919 AA577730 Hs 188684 ESTs, Weakly similar to PC4259 ferπtin 1 7
127773 AA725863 Hs 120508 ESTs 1 7
126495 AB029021 Hs 137732 KIAA1098 protein 1 7
126948 AW968535 Hs 14328 hypothetical protein FU20071 1 7
126671 C03105 Hs 285847 CGI-19 protein 1 7
115428 AA284112 Hs 94680 ESTs, Weakly similar to I78885 serme/t 1 7
128232 AI830319 Hs 334641 hypothetical protein DKFZp434l1916 1 7
126082 H81188 Hs 269571 ESTε 1 7
120467 AW292562 Hs 187628 ESTs 1 7
124041 AW590171 Hs 101413 ESTs 1 7
105012 AF098158 Hε 9329 chromosome 20 open reading frame 1 1 7
123951 AB012922 Hs 173043 metastasis-assxiated 1-lιke 1 1 7
126449 AF223944 Hs 325443 breast cell glutaminase 1 7
124554 N65961 gb za27d03 s1 Soares fetal liver spleen 1 7
133651 AI301740 Hs 173381 dihydropyπmidiπase like 2 1 7
126780 R12421 Hs 5811 chromosome 21 open reading frame 59 1 7
125661 AA491830 Hs 25689 ESTs 1 7
125888 H18298 gb yn48b09 r1 Soares adult brain N2b5HB5 1 7
127245 AA323958 gb EST26810 Cerebellum II Homo sapiens c 1 7
111223 AA852773 Hs 334838 KIAA1866 protein 1 7
115611 R44789 Hs 33191 Homo sapiens, Similar to transmembrane r 1 7
124846 R59977 Hs 158196 traπscnptioπal adaptor 3 (ADA3, yeast 1 7
100397 D84424 Hs 57697 hyaluronan synthase 1 1 7
127180 T27097 Hs 22790 ESTs 1 7
102598 BE250742 Hε 106673 eukaryotic translation initiation factor 1 7
134076 AF086215 gb Homo sapiens full length insert cDNA 1 7
115659 W99382 Hε 283709 popolyεxchaπde εpxific response-7 p 1 7
125555 R19382 Hs 117869 ESTs 1 7
128382 AI138886 Hs 143243 ESTs 1 7
127710 AA682867 Hs 191901 ESTs 1 7
125445 AI452722 Hs 7709 WW domain binding protein 1 1 7
129951 AL110282 Hs 268024 Homo sapiens, clone IMAGE 3873720, mRNA 1 7
119898 R93325 Hs 58690 ESTs 1 7
129703 BE388665 Hs 179999 Homo sapiens, clone IMAGE 3457003, mRNA 1 7
133531 BE276738 Hs 74578 DEAD/H (Asp-Glu-Ala-Asp/His) box polypep 1 7
119726 AF086289 Hs 234766 skiπ-spxific protein 1 7
125198 W69474 Hs 323140 ESTs 1 7
121414 AW291477 Hε 188763 testis expressed sequence 13A 1 7
112542 AI458867 Hs 24276 ESTs 1 7
101368 M13058 Hs 73952 prolme-πch protein Haelll subfamily 2 1 7
125820 AA730136 Hε 75561 teratocarcmoma-deπved growth fxtor 1 1 7
129091 AA056483 Hs 301463 Human Chromosome 16 BAC clone CIT987SK-A 1 7
132609 U20165 Hs 53250 bone morphogenetic protein rxeptor, typ 1 7
119447 W31714 Hs 122656 ESTs, Highly similar to formin 2-lιke pr 1 7
113675 T81034 Hs 14841 ESTε 1 7
113701 T97301 Hs 18026 ESTs 1 7
116180 AA463902 Hs 13522 ESTs, Weakly similar to I38022 hypothet 1 7
127133 AA280740 Hs 292072 ESTs, Moderately similar to A46010 X-lin 1 7
113316 T70318 Hs 268581 ESTs 1 7
123316 AI290561 Hs 155361 ESTs 1 7
122638 AL137476 Hs 123609 Homo sapiens mRNA, cDNA DKFZp434l0623 (f 1 7
105053 AI884911 Hs 32989 rxeptor (calcitonin) xtivity modifying 1 7
103305 X82279 gb H sapiens Fas, Apo-1 gene (promoter a 1 7
110384 H45282 Hs 268798 ESTs 1 7
115626 AW630870 Hs 86674 ESTs, Weakly similar to hypothetical pro 1 7
126905 AW504027 Hs 15301 Homo sapiens cDNA FLJ12596 fis, clone NT 1 7
130820 AL353934 Hs 288798 hypothetical protein FLJ21012 1 7
112394 AK000373 Hs 8358 hypothetical protein FLJ20366 1 7
129589 AW504292 Hs 11517 ESTε 1 7
126446 NM 015670 Hs 118926 sentnn/SUMO-specific protease 3 1 7
126547 U47732 Hs 84072 transmembrane 4 superfamily member 3 1 7
120287 AF219946 Hs 102237 tubby super-family protein 1 7
129991 R28386 Hs 179925 ESTs, Weakly similar to ALU8 HUMAN ALU 1 7
123912 AA621283 Hs 332855 EST 1 7
102071 AL120051 Hs 144700 ephππ Bl 1 7
121046 AB033083 Hε 97377 KIAA1257 protein 1 7
128403 AI908006 Hε 295362 Homo sapiens cDNA FLJ14459 fis, clone HE 1 7
104268 AL043864 Hs 70604 ATPase, Class II, type 9A 17
111598 R11505 Hs 268912 ESTs 1 7
128109 AW269421 Hs 128093 ESTs 1 7
125435 R08480 Hs 272138 ESTs Weakly similar to ALU1.HUMAN ALU S 1 7
133104 AI091195 Hs 65029 growth arrest specific 1 1 7 126826 AA099764 gb zn61f12 r1 Stratagene muscle 937209 H 17
106483 NM 006548 Hs 30299 IGF-II mRNA binding protein 2 17
129765 M86933 Hs 1238 amelogemn (Y chromosome) 17
115904 AI167560 Hs 61297 ESTs 17
125514 AB040912 Hs 191098 hypothetical protein FU11598 17
125797 H03117 Hs 111497 similarto mouse neuronal protein 15 6 17
133179 U81599 Hs 66731 homeo box B13 17
115167 AA749209 Hs 43728 hypothetical protein 17
118036 AI471862 Hs 196008 Homo sapiens cDNA FLJ 11723 fis, clone HE 17
124540 N63232 gb yz39a12 s1 Morton Fetal Cxhlea Homo 17
126183 BE018708 Hs 81972 SHC (Src homology 2 domain-containing) t 17
127897 AA773681 gb af77b12 r1 Soares.NhHMPu.S1 Homo sapi 17
126680 F07097 Hs 133865 transmembrane 6 superfamily member 1 17
126972 NM 016255 Hs 95260 Autosomal Highly Conserved Protein 17
130605 BE514362 Hs 306024 FK506 binding protein 3 (25kD) 17
127541 AA573449 Hs 171515 ESTs 17
127392 A1816736 Hs 14896 DHHC1 protein 17
106879 AI190785 Hs 33020 Homo sapiens, clone IMAGE 3939163, mRNA, 17
128303 AI096444 Hs 7187 hypothetical protein FLJ10707 17
126469 BE384361 Hs 182885 ESTs, Weakly similar to JC5024 UDP-galac 17
125756 BE174587 Hs 289721 growth arrest specific transcript 5 17
132332 AW978906 Hs 45005 hypothetical protein FLJ 12960 16
127142 AW452942 Hs 130393 ESTs 16
128416 F13165 Hs 12549 ESTs, Weakly similar to 2109260A B cell 16
103790 AL122044 Hs 331633 hypothetical protein DKFZp566N034 16
134578 AL110193 Hs 224137 hypothetical protein 16
110023 AW294701 Hs 31040 ESTs 16
125511 AJ271379 Hs 76194 ribosomal protein S5 16
111483 R06569 Hs 269534 ESTs 16
127363 AF064104 Hs 22116 CDC14 (cell division cycle 14 S cerevi 16
126231 AA991766 Hs 300793 ESTs 16
106181 AI803651 Hs 191608 ESTs 16
114767 AI859865 Hs 154443 minichromosome maintenance deficient (S 16
119929 W86464 Hs 304825 ESTs 16
132542 AL137751 Hs 263671 Homo sapienε mRNA, cDNA DKFZp434I0812 (f 16
127155 AA284983 gb zt23e10 r1 Soareε ovary tumor NbHOT H 16
125956 AK000214 Hs 129014 hypothetical protein FU20207 16
126854 AJ275986 Hs 71414 transcnption factor (SMIF gene) 16
131330 D13969 Hs 184669 zinc finger protein 144 (Mel-18) 16
129445 W52452 Hs 29797 πbosomal protein L10 16
113427 T85105 Hs 15471 ESTs 16
106124 H93366 Hs 7567 Homo sapienε cDNA FLJ21962 fis, clone H 16
128135 AA954381 Hs 269721 ESTs, Moderately similar to ALU1 HUMAN 16
111460 R02728 Hs 117331 ESTε 16
125636 H12382 Hs 25119 ESTs, Weakly similar to YEX0.YEAST HYPOT 16
134118 BE336680 Hs 182877 KIAA0116 protein 16
111570 AF059203 Hs 20580 sterol O-xyltransferase 2 16
113511 T89578 Hs 189740 ESTs 16
113296 AW449560 Hs 89576 Inner mitochondnal membrane peptidase 2 16
109875 H03260 Hε 30385 ESTs 16
105930 AF016371 Hs 9880 peptidyl prolyl isomerase H (cyclophilm 16
105564 BE616694 Hs 288042 hypothetical protein FLJ 14299 16
128063 AI377750 Hs 167177 ESTs 16
109779 AB029396 Hε 3353 beta-1,3-glucuronyltransferase 1 (glucur 16
125334 T86569 Hs 182118 ESTs 16
127206 AW816490 Hs 337508 ESTs 16
108845 AW362901 Hs 68864 ESTε, Weakly similar to phosphatidylεeπ 16
132520 AA257992 Hs 50651 Janus kinase 1 (a protein tyrosine kinas 16
114062 AI560984 Hs 27283 ESTs 16
122550 AA451859 Hε 99253 ESTs 16
113413 R08872 Hε 186512 ESTs 16
127019 AI929355 Hs 286128 hypothetical protein FU23329 16
106251 R12607 Hs 35101 proline-πch Gla (G-carboxyglutamic xid 16
112670 AL138012 Hs 183840 ESTs, Moderately similar to ALU7_HUMAN A 16
114913 AI435199 Hs 58940 ESTs, Weakly similar to I38022 hypotheti 16
126604 AI023299 Hs 269806 ESTs 16
125324 R07785 gb yf15c06 r1 Soares fetal liver spleen 16
121438 AW445024 Hs 139389 ESTs 16
127289 AI041014 Hs 220752 ESTs, Weakly similarto unnamed protein 16
126935 AI198535 Hs 89463 potassium large conductance calcium xti 16
132430 AW973652 Hs 283105 ESTs 16
133541 H75334 Hs 11050 F-box only protein 9 16
102612 U65402 Hs 248124 G protein-coupled rxeptor 31 16
120228 AI192528 Hs 164537 ESTs 16
122652 AA454641 gbzx99d05ε1 Soares.NhHMPu.S1 Homo sapi 16
103456 AA496425 Hs 9629 papillary renal cell carcinoma (translx 16
105355 AL031 47 Hs 26938 Homo sapiens, clone IMAGE 4053044, mRNA, 16
108043 AA042873 Hs 160412 ESTs 16
128695 NM.003478 Hs 101299 cullm 5 16
127984 AA846377 Hs 193706 ESTs, Weakly similar to ALU8.HUMAN ALU S 16
124405 AA228137 Hs 25005 hypothetical protein MGC3329 16
103934 BE278111 Hs 134200 DKFZP564C186 protein 16
124195 H83034 gb yq48e07 r1 Soares fetal liver spleen 16 110838 N48982 Hs 38034 Homo sapiens cDNA FLJ12924 fis, clone NT 16
102687 NM.007019 Hs 93002 ubiquitin carrier protein E2-C 16
121226 AA364109 Hs 177990 ESTs 16
120415 AA235810 gb zs41a03 s1 Soares_NhHMPu_S1 Homo sapi 16
123864 AA620882 gb af95g01 s1 SoaresJestιs_NHT Homo sap 16
125045 AH14630 Hs 208334 Homo sapienε cDNA FLJ21874 fis, clone H 16
133425 AA444390 Hs 155482 hydroxyacyl glutathione hydrolase 16
126578 AF151861 Hs 107528 androgen induced protein 16
102406 U43177 (NONE) 16
114126 BE566962 Hs 7063 Homo sapiens cDNA FLJ20913 fis, clone A 16
125233 W85713 Hs 110092 ESTs 16
109635 F042S6 Hs 169161 ESTs Highly similarto MAON_HUMAN NADP- 16
125675 BE294972 Hs 56406 Homo sapiens cDNA FU13549 fis, clone PL 16
129707 AW572317 Hs 12082 Homo sapiens mRNA, cDNA DKFZp566L203 (fr 16
127569 AI765107 Hs 274422 hypothetical protein FLJ20550 16
113302 T66919 Hs 268575 ESTs 16
119705 AI984203 Hs 57874 ESTs 16
127226 AL036559 Hs 3463 nbosomal protein S23 16
123489 AA599708 gb ag11a10 s1 Gesεler Wilms tumor Homo s 16
107468 AA740979 Hs 91389 ESTs 16
115916 AI052731 Hs 91910 ESTs 16
127815 AA743490 Hs 255015 ESTs 16
100364 NM 004341 Hs154868 carbamoyl phosphate synthetase 2, aspart 16
125568 AW615396 Hs 105613 ESTs 16
105260 N81201 Hs 31755 ESTs 16
125659 T57693 Hs 87929 Homo sapiens cDNA FLJ13707 fis, clone PL 16
111275 N70970 Hs 35006 ESTs 16
106542 AA339541 Hs 24956 hypothetical protein FLJ22056 16
133423 T84084 Hs 196008 Homo sapiens cDNA FLJ 11723 fis, clone HE 16
124770 AA984414 Hs 120429 ESTs 16
117936 AI382904 Hs 47213 ESTs 16
134385 M14660 Hs 169274 ESTs, Highly similar to IFT2.HUMAN INTER 16
108367 AW410478 Hs 104019 transforming, xidic coiled-coil contain 16
131143 NM 000312 Hs2351 protein C (inactivator of coagulation fa 16
105441 N28522 Hs 8935 quiπolmate phosphoπbosyltransferase (n 16
128215 AA973310 gb op91e06 s1 Soares_NFL.T_GBC.S1 Homo s 16
127344 AI003929 Hs 80624 hypothetical protein MGC2560 16
126478 BE541249 Hs109697 ESTs 16
122053 AI637498 Hs 98745 ESTs 15
111760 BE551929 Hs 268754 Homo sapiens cDNA FLJ11949 fis, clone HE 15
112401 R61279 Hs 237536 ESTs, Weakly similar to AF151067 1 HSPC2 15
103023 AW500470 Hs 117950 multifunctional polypeptide similar to S 15
125575 H14983 gb ym19h09 r1 Soares infant brain 1NIB H 15
128765 AF073310 Hs 143648 insulin receptor substrate 2 15
108935 AA147848 Hs 67991 hypothetical protein DKFZp434G0522 15
121221 AI140708 Hε 97461 ESTs 15
120091 AW024672 Hs 59558 EST 15
107375 BE011845 Hs 251064 high mobility group (nonhistoπe chromoso 15
125803 AW876115 Hs 29852 ESTs 15
115132 AA811762 Hs71433 ESTs 15
113346 AF143876 Hs 14318 Homo sapiens clone IMAGE 113399 mRNA seq 15
107357 U63973 Hs 103501 rhodopεm kinase 15
125443 BE251057 Hs 177592 ribosomal protein, large, P1 15
133803 M24461 Hs76305 surfactant, pulmonary-assxiated protein 15
113378 T80738 Hs 14757 ESTs 15
105540 BE391690 Hs 9265 hypothetical protein FU20917 15
127446 F13008 gb HSC3HE011 normalized infant brain cDN 15
134075 NM 012201 Hs 78979 Golgi apparatus protein 1 15
127585 AA604144 Hs 190632 ESTs 15
125824 Z45258 Hs 286013 short coiled-coil protein 15
127606 AA621135 Hs 136552 ESTs 15
125585 AW298113 Hs 92909 SON DNA binding protein 15
107757 BE621721 Hs 280792 hypothetical protein FLJ12387 similarto 15
109878 H09356 Hs 22528 ESTs 15
132297 BE272446 Hs 265317 hypothetical protein MGC2562 15
115784 AW402151 Hs 54673 tumor nxrosis fxtor (ligand) superfami 15
127880 W39735 Hs73818 ubiquiπol-cytochrome c redu ase hinge p 15
102305 AL043202 Hs 90073 chromosome segregation 1 (yeast homolog) 15
102868 X02419 Hs 77274 plasminogen xtivator, urokmase 15
133457 J04948 Hs 333509 alkaline phosphatase, plxental-like 2 15
130339 AA435746 gb zt79e03 si Soares.testis.NHT Homo sap 15
125444 N28476 Hs 159161 Rho GDP dissxiation inhibitor (GDI) alp 15
123470 AW303285 Hs 303632 Human DNA sequence from clone RP11-110H4 15
100025 15
127063 AI276526 Hε 331564 Homo sapiens mRNA, cDNA DKFZp434H1215 (f 15
127945 AA815031 Hs 123598 ESTs 15
111557 R09510 Hs 20373 EST 15
116009 AW137635 Hε 44238 ESTs Weakly similar to S65657 alpha-1 C- 15
119858 W01370 Hs 46824 ESTs 15
106509 AI042309 Hs 64552 hypothetical protein MGC15563 15
124124 AW294404 Hs 144515 Homo sapiens cDNA FLJ 11672 fis, done HE 15
126713l AW249181 Hs 19954 ESTs, Weakly similar to T19873 hypotheti 15
126475i AW959075 Hs 238797 ESTs, Moderately similar to I38022 hypot 15 126851 R40611 Hs 137565 ESTs 15
104820 - AW162768 Hs 22620 ESTs 15
127235 A1817309 Hs 225583 ESTε, Weakly similar to 2004399A chromos 15
126552 AF168711 Hs 159397 x 010 protein 15
127523 AA617637 gb np34h12 s1 NCI CGAP.Lul Homo sapiens 15
131692 BE559681 Hs 30736 KIAA0124 protein 15
112974 AL353965 Hs 101174 microtubule-associated protein tau 15
118921 N91914 Hs 54751 ESTs 15
100676 X02761 Hs 287820 fibronectin 1 15
127721 T59578 Hs 188440 ESTs, Weakly similar to ALUF.HUMAN »« 15
115254 AA279024 Hs 269316 ESTs, Weakly similar to S65657 alpha-1 C 15
128173 AI457242 Hs 127024 ESTε 15
126846 AA663527 Hs 116910 ESTs 15
125294 R40025 Hs 106551 ESTs 15
127494 AW978730 Hs 291956 ESTs, Weakly similar to ALU8_HUMAN ALU S 15
134191 W26632 Hs 7979 KIAA0736 gene product 15
107394 AA864798 Hs 186180 Homo sapiens cDNA FLJ23038 fis, clone L 15
131562 NM 003512 Hs 28777 H2A histone family, member L 15
127310 AW450671 Hs 189284 ESTs 15
122359 AA523486 gb nι67f11 si NCI_CGAP_Pr12 Homo sapienε 15
100524 M80902 Hs 183704 ubiquitin C 15
128422 T77794 gb yd20d09 r1 Soares fetal liver spleen 15
129902 AA076278 Hs 13277 hypothetical protein FLJ22054 15
126784 T81887 Hs 108854 HSPC163 protein 15
123343 AI761902 Hs 99597 ESTs 15
105458 AW954377 Hs 26412 nng finger protein 26 15
112266 AI652534 Hs 25934 ESTs, Weakly similar to HSHU11 histone H 15
127622 AA628222 Hs 97883 ESTs 15
113659 R06545 Hs 189781 ESTs, Weakly similar to ALU1 HUMAN ALU S 15
116892 AI573283 Hs 38458 ESTs 15
126995 NM 014351 Hs 189810 sulfortranferase family 4A member 1 15
111657 R07364 Hs 268667 ESTs, Weakly similar to ALU1.HUMAN ALU 15
100243 AB028125 Hs 77854 regucalcm (senescence marker proteιn-30 15
116153 AF107203 Hs 57937 ataxin 2-bιndιng protein 1 15
108892 AK000002 Hs 55879 Homo sapiens mRNA, cDNA DKFZp434L0827 (f 15
113294 AI037922 Hs 11000 leptin rxeptor overlapping transcnpt I 15
126691 W03046 Hs 283664 aspartate beta-hydroxylase 15
106979 AW015227 Hs 289053 hypothetical protein FLJ14733 15
125546 H09950 gb ym01d12 r1 Soares infant brain 1NIB H 15
113990 AI497945 Hs 83097 hypothetical protein FU22955 15
129295 U63127 Hs 110121 SEC7 homolog 15
125431 AW851639 Hs 75584 polymyositis/scleroderma autoantigen 2 ( 15
112558 AK001621 Hs 15921 hypothetical protein FLJ10759 15
122046 AI560456 Hs 107319 ESTs 15
122472 AA448509 Hs 128652 ESTε 15
130753 AA205223 Hs 189 phosphodiesterase 4C, cAMP-spxific (dun 15
131714 AA642831 Hs 31016 putative DNA binding protein 15
101233 AL135173 Hs 878 sorbitol dehydrogenaεe 15
109501 AF047437 Hε 90436 εperm assxiated antigen 7 15
126984 AA213820 Hs 256533 ESTs, Weakly similar to S11998 finger pr 15
125765 BE243877 Hε 76941 ATPase, Na+/K+ transporting, beta 3 poly 15
127693 AA676727 gb zj68b11 s1 Soares_fetal_lιver_εpleen_ 15
128453 X02761 Hs 287820 fibronxtin 1 15
119418 T97590 Hs 221711 ESTs, Weakly similar to ALU1.HUMAN ALU 15
132669 W38586 Hs 293981 guanine nucleotide binding protein (G pr 15
116708 F10528 Hs 70001 ESTε, Moderately similar to JC6169 nucl 15
122420 AA446971 gb zw85f11 s1 Soares_total_fetuε_Nb2HF8_ 15
100238 L24959 Hs 348 calcium/calmodulin dependent protein kin 15
109710 D20044 Hs 12929 hypothetical protein FU20721 15
105704 AI282341 Hs 75431 fibπnogeπ, gamma polypeptide 15
112712 R91060 Hs 330761 ESTε 15
100088 AF003743 gb Homo εapiens delayed rectifier potass 15
114122 R46128 Hs 12751 ESTs 15
132397 AA021160 Hs 4750 hypothetical protein DKFZp564K0822 15
107881 AI568350 Hε 61273 hypothetical protein MGC2650 15
106302 AA398859 Hs 18397 hypothetical protein FLJ23221 15
125898 AK001823 Hs 92287 Homo sapiens mRNA, cDNA DKFZp564C2478 (f 15
104957 AI359009 Hs 10026 mitochondnal πbosomal protein L17 15
102909 NM 005269 Hs 2693 glioma-assxiated oncogene homolog (zinc 15
125559 BE297488 Hs 279877 cell diviεion protein FtεJ 15
109634 H17063 Hs 183646 ESTε 15
116607 W05238 Hs 94316 ESTs, Weakly similarto T31613 hypotheti 15
127175 R11937 gb yf54b08 r1 Soares infant brain 1NIB H 15
110617 W93231 Hs 285901 Homo εapienε, clone IMAGE 3948563, mRNA, 15
125988 W27648 gb 37e10 Human retina cDNA randomly pnm 15
115093 AI241932 Hs 3542 hypothetical protein FU11273 15
121207 AA705799 Hs 183714 ESTε 15
112652 : BE269699 Hs 235782 εolute camerfamily 21 (organic aπioπ 15
125213 l AB014554 Hs 109299 protein tyrosine phosphatase, rxeptor t 15
125912 I AW867467 Hs 278712 eukaryotic translation initiation factor 15
133046 i R96881 Hs 63609 Hpall tiny fragments Ixus 9C 15
122791 AL122055 Hs 129836 KIAA1028 protein 15 Table 26B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank accession numbers
Pkey CAT number Accession
108451 13766 27 AA079195 AA084955 AA126308 AA084956
124185 2606 3 H83034 H52379
123619 371681 1 AA602964 AA609200
125165 1852047.1 W45350 W45406
125324 1692163 1 R07785T85948 T86972
126053 1601238 1 H64450 H64464
126086 1606216 1 H75681 H70975
126098 1629789 1 M79088 N88221
125464 168460 1 N71807 AA203399
125499 1562851 1 H10543 R11878
126127 1205826 1 N95428 W24040 AW751366 H81987
125546 356478 1 H09950 R18413 AA570553 AW973425
125549 1702179 1 R20215 R18767
125558 1703083 1 R59305 R19748
125575 1566885.1 H14983 R21554
125743 5025 5 H17151 H11956
125761 1744008 1 R68351 R68364
126426 110687.Ϊ AA125984 AA127189AA065075 AA070377 AA100017
AA079891 AA113255 AA075168 AA082764 AA083380 N84829 AA084752 AA076512 AA085119 AA085208 AA085045
127155 200358 1 AA284993 AA478122 AA477923
127175 1695805 1 R11937 Z45532
126528 1276201 1 Z24895 AW891336 R01294
125957 1583542 1 H41694 H45213
125976 296453 1 AA436760 AW237453 BE327496 N47347 N56967
125982 1766315 1 R98091 W92898
125988 1365728 1 W27648 R99193 BE090398
127245 226662.1 AA323958AA370268
127248 227560 1 AA364195 AA325029 AW962050
127262 231725 1 AA828125 AA834883 AA330555
126659 1541209 1 T16245 R19694 F13545 H10299 T66048 T65279 H18006
126693 87363 1 C05723 AA018342
127315 37938 1 AF116622 AH 14507 AA640834 AA377999
126730 297653 1 AA442429 T19477
103898 187213 -3 AA248884
127446 16001 2 F13008 T75435
126826 127356 1 AA099764 AA112950
126872 142696.1 AW450878 AA136653AA136656 AW419381 AA984358 AA492073, BE168945 AA809054 AW238038 BE011212 BE011359 BE011367 BE011368 BE011362 BE011215 BE011365 BE011363
128132 177108.1 AA225632 AI820970 AI820952 AA226472 AI732140 AI732059 AA226307 AA225500
127523 351071.1 AA617637 AA554963
126982 171753 1 AA211419 AA211566
128215 530345 -1 AA973310
127704 405690 1 AA679609 AA694592
127705 966283 2 AJ003322AJ003324
128422 1811283 1 T77794 T85681
127897 446527 1 AA773681 AA773857
120734 208882 1 AA299948 AA299949
100098 25117 -13 AF003743
114620 32062.8 AA642974 AA084223
122652 26401 -30 AA454641
100842 tιgr_HT4398 U05597
123783 genbank_AA610112
125032 genbank_T74884
123808 genbaπk_AA620552
123864 genbank_AA620882
118049 genbank N53145
102406 entrez_U43177
116962 genbank H79677
134076 40321 1 AF086215 W02702 AA284288 W25655
125888 266863 1 H18298 H46830
127271 321389.1 H96820 H79463
113119 genbank_T47910 T47910
104799 genbank_AA029703 AA029703
127693 790317.1 AA676727AA704704
120415 genbank AA235810 AA235810
127964 135151.1 F06298 R18057
122359 681003.1 AA523486 AW026780 AI821660 AA443898
122420 genbank_AA446971
124276 genbaπk_H83465
101447 entrez_M21305
124540 genbank_N63232
124554 genbank_N65961
117357 genbank N24829
103305 entrez_X82279 103392 entrez_X94563 119416 genbank T97186 105225 genbank_AA211777 121292 genbank_AA401807 112853 genbank_T02843 121387 genbank_AA405854 114601 genbank_AA075566 100221 entrez_D28383 130339 genbank_AA435746 100554 tιgr_HT2241 123423 genbank_AA598484 123474 genbank_AA599209 123489 genbank_AA599708
TABLE 27A ABOUT 895 GENES UP-REGULATED IN COMBINED LUNG FIBROSIS COMPARED TO NORMAL BODY
Table 27A lists about 895 genes that are upregulated in lung fibrosis (collection of IPF, HP, and NSIP) sampleε as compared with the nomial "body map" samples These were selected from about 59680 probesets on an Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" fibrosis sample expression level to "average" normal adult tissues was greater than or equal to about 20 The "average" fibrosis sample expression level was set to the 90* percentite amongst fibrosis samples The "average" normal adult tissue level was εet to the 95* percentite amongεt non-malignant tissues In order to remove gene specific background levels of non-specific hybridization, the 15* percentile value amongst non malignant tissues was subtracted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of fibrasis to normal body tissue
Pkey ExAccn Unigene ID Unigene Title R1
431164 AA493650 Hs 94367 Homo sapiens cDNA FU23494 fis, clone L 560
424917 AI636208 Hs 96901 Homo sapiens cDNA FU23049 fis, clone L 265
453310 X70697 Hs 553 solute carrier family 6 (neurotransmitte 25 5
457200 U33749 Hs 197764 thyroid transcnption factor 1 222
414517 M24461 Hs 76305 εurfactant pulmonary-associated protein 21 1
429272 W25140 Hs 110667 ESTs 19 4
418007 M13509 Hs 83169 matrix metalloprotemase 1 (interstitial 19 1
442006 AW975183 Hs 292663 ESTs 188
445885 AI734009 Hs 127699 KIAA1603 protein 180
440452 AI925136 Hs 55150 ESTs, Weakly similar to CAYP.HUMAN CALCY 17 8
422426 W79117 Hs 58559 ESTs, Weakly similar to rhotekin [M muse 174
444929 AI685841 Hs 161354 ESTs 16 5
440807 AW269421 Hs 128093 ESTs 163
408826 AF216077 Hs 48376 Homo sapiens clone HB-2 mRNA sequence 14 2
446967 AI699629 Hs 156781 ESTs 133
417801 AA417383 Hs 82582 integπn, beta like 1 (with EGF-like rep 123
437119 AI379921 Hs 177043 ESTs 123
451103 R52804 Hε 25956 DKFZP564D206 protein 11 5
443450 N66045 Hs 133529 ESTs 11 4
411880 AW872477 gb hm30f03 x1 NCI CGAP Thy4 Homo sapiens 11 3
432519 AI221311 Hs 130704 ESTs 11 3
414142 AW368397 Hs 150042 ESTs 11 0
433283 BE041135 Hs 175622 ESTs 101
441082 AW444804 Hs 202655 ESTs 10 1
452039 AI922988 Hs 172510 ESTs 100
417204 N81037 Hs 1074 surfactant, pulmonary-assxiated protein 99
421952 AA300900 Hs 98849 ESTs, Moderately similar to AF161511 1 H 98
412372 R65998 Hs 118615 ESTs 98
426274 D38122 Hs 2007 tumor nxrosiε factor (ligand) εuperfami 97
431007 AF039564 Hs 248211 retinoblastoma-binding protein 9 94
443709 AI082692 Hs 134662 ESTs 93
446232 AI281848 Hs 165547 ESTs 92
448253 H25899 Hs 201591 ESTs 92
432133 AB033088 Hs 272567 KIAA1262 protein 9 1
409238 AL049990 Hs 51515 Homo sapiens mRNA, cDNA DKFZp564G112 (fr 90
431353 AA828032 Hs 189076 ESTs 88
450050 AI681268 Hs 257883 ESTs 88
458194 AW383618 Hs 265459 ESTs, Moderately similar to ALU2 HUMAN A 88
414968 C16096 Hs 297777 ESTs 87
425664 AJ006276 Hs 159003 transient rxeptor potential channel 6 87
408562 AI436323 Hs 31141 Homo sapiens mRNA for KIAA1568 protein, 86
453672 U73531 Hs 34526 G protein-coupled rxeptor 85
429420 AK001679 Hs 202289 hypothetical protein FLJ10376 85
421478 AI683243 Hs 97258 ESTs 84
404916 84
444396 T65213 Hs 4257 ESTs 83
442275 AW449467 Hs 54795 ESTs 83
437479 R61866 Hs 101277 ESTs 82
432203 AA305746 Hs 49 macrophage scavenger receptor 1 82
431433 X65018 Hs 253495 surfactant pulmonary-assxiated protein 79
406747 AI925153 Hs 217493 annexm A2 78 445537 AJ245671 Hs 12844 EGF-like domain, multiple 6 77
450025 AK001875 Hs 24321 Homo sapiens cDNA FLJ12028 fis, clone HE 76
421798 N74880 Hs 264330 N acylsphingosme amidohydrolase (acid c 75
421155 H87879 Hs 102267 lysyl oxidase 75
446917 A1347863 Hs 156672 ESTs 75
422798 R92347 Hs 34574 ESTs 74
426830 AA385751 Hs 160392 ESTs 74
437157 BE048860 Hs 120655 ESTs 74
433231 AB040926 Hs 143552 KIAA1493 protein 73
451561 N52812 Hs 177403 ESTs 71
430656 AA482900 Hs 162080 ESTs 71
448206 BE622585 Hs 3731 ESTs 71
420209 AA256444 Hs 32295 Homo sapiens cDNA FLJ12604 fis, clone NT 70
426803 AA362568 Hs 179747 ecotropic viral integration site 5 69
427383 NM 005411 Hs 177582 surfactant pulmonary-associated protein 69
409718 D86640 Hs 56045 src homology three (SH3) and cysteine π 68
443324 R44013 Hs 164225 ESTs 68
431924 AK000850 Hs 272203 Homo sapiens cDNA FLJ20843 fis, clone AD 68
427356 AW023482 Hs 97849 ESTs 67
418735 N48769 Hs 44609 ESTs 67
429945 NM 006729 Hs 226483 diaphanous (Drosophila, homolog) 2 66
407510 U96191 gb Human trophoblast hypoxia regulated f 66
430099 AW194988 Hs 20537 Homo sapiens cDNA FLJ13942 fis, clone Y7 66
441835 AB036432 Hs 184 advanced glycosylation end product spxi 65
428508 BE252383 Hs 184668 SBBI31 protein 65
438202 AW169287 Hs 22588 ESTs 65
441233 AA972965 Hε 135568 ESTs 64
433384 AI021992 Hs 124244 ESTs 63
427043 AA397679 Hs 298460 ESTs 63
425921 NM 007231 Hs 162211 solute carrier family 6 (neurotransmitte 63
438909 AF085839 gb Homo sapiens full length insert cDNA 63
433365 AF026944 Hs 293797 ESTs 63
456964 H59846 Hs 128355 ESTs, Moderately similar to ALU7.HUMAN A 62
445186 AW614544 Hs 123641 protein tyrosine phosphatase, receptor t 62
431337 N48107 Hs 292593 ESTs 61
434819 AA650099 Hs 291541 ESTs 60
458219 H22195 Hs 31874 ESTs 60
434377 AW137148 Hs 136348 osteoblast spxific factor 2 (fascidin 59
435933 AA805520 Hs 192075 ESTs 59
436954 AA740151 Hs 130425 ESTs 59
445424 AB028945 Hs 12696 cortxtin SH3 domain-binding protein 58
449108 AI140683 Hs 98328 ESTs 58
410334 AW979261 Hs 291993 ESTs 57
447112 H17800 Hs7154 ESTs 57
447700 AI420183 Hs 171077 ESTs, Weakly similar to similar to seπn 57
449208 AW263635 Hs 48643 ESTs 57
445657 AW612141 Hs 279575 ESTs 57
421554 AW137676 Hs 97775 ESTs, Weakly similar to Testiε-εpxific 57
435299 AI745458 Hs 122614 ESTs, Weakly similar to apoptotic protea 56
416769 AI339257 Hs 115436 ESTs 56
433527 AW235613 Hs 133020 ESTs 56
452771 T05477 gb EST03366 Fetal brain, Stratagene (cat 56
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph 55
411514 AW850178 Hs 18995 KIAA1304 protein 55
424084 AI940675 Hs 20914 Homo sapiens cDNA FLJ23056 fis, clone L 55
444527 NM.005408 Hs 11383 small inducible cytokine subfamily A (Cy 54
429710 AI337113 Hs 146025 Homo sapiens cDNA FU23594 fis, clone L 54
432113 AA935065 Hs 152385 ESTs 54
447997 H00656 Hs 29792 ESTs 54
449328 AI962493 Hs 197647 ESTs 53
416575 W02414 Hs 38383 ESTs 53
432009 AL137424 ' gb Homo sapiens mRNA, cDNA DKFZp761G2123 53
434088 AF116677 Hs 249270 hypothetical protein PR01966 53
444342 NM.014398 Hε 10887 similar to lysosome-assxiated membrane 52
414299 AA142989 Hs 71730 ESTs 52
431041 AA490967 Hs 105276 ESTε 52
448104 AI674818 Hs 178391 πbosomal protein L44 52
445279 R41900 Hs 22245 ESTs 51
408978 AL133617 Hs 49421 Homo sapiens mRNA, cDNA DKFZp434M0728 (f 51
415094 D59513 gb HUM042H10B Clontxh human fetal brain 51
428244 AI564123 Hs 2500 ADP-nbosylation fxtor-like 5 51
452784 BE463857 Hs 151256 I Homo sapiens cDNA FU21062 fis, clone C 51
455431 AW938484 Hs 80738 sialophoπn (gpL115, leukosialin, CD43) 51
449416 AI651016 Hs 246311 I ESTs 51
421659 NM.014459 Hs 106511 I protocadhenn 17 51
407638 AJ404672 Hs 28869: i Homo sapiens cDNA FLJ11667 fis, clone HE 50
446164 AW273539 Hs 19932! ) Homo sapiens cDNA FLJ23577 fis, clone L 50
413048 M93221 Hs 75182 mannose rxeptor, C type 1 50
446608 N75217 Hs 257846 ESTs 49
419807 R77402 gb yι75f11 s1 Soares placenta Nb2HP Homo 49
447164 AF026941 Hs 17518 Homo sapiens cιg5 mRNA, partial εequence 49
442652 AI005163 Hε 201378 ESTs, Weakly similar to KIAA0944 protein 49
429496 AA453800 Hs 192793 ESTs 48 429859 NM_007050 Hs 225952 protein tyrasine phosphatase rxeptor t 48 432824 AK001783 Hs 279012 hypothetical protein FLJ10921 48 425509 AF079363 Hs 158213 sperm asεociated antigen 6 48 424717 H03754 Hε 152213 wingless type MMTV integration site fami 48 5 436061 AI248584 Hs 190745 Homo sapienε cDNA FLJ21326 fis clone C 48
444218 AF070641 Hs 10684 Homo sapiens clone 24421 mRNA sequence 47 453382 AA709285 Hs 5997 Homo sapienε cDNA FLJ 13078 fis clone NT 47 447033 AI357412 Hs 157601 ESTs 47 417235 AA810278 Hs 24250 ESTs 47 10 418200 AW629751 Hs 206654 ESTs, Weakly similar to alternatively sp 47
427652 AI673025 Hs 43874 ESTs 47 431255 AA497043 Hs 115685 ESTs 47 441143 AI027604 Hs 159650 ESTs 47 452293 AI871833 gb wm51h09 x1 NCI CGAP Ut2 Homo sapiens 47 15 443903 AI220547 Hs 135223 ESTs 47
422352 AA766296 Hs 99200 ESTs 47 424105 AI142336 Hε 43977 ESTs 46 439759 AL359055 Hs 67709 Homo sapiens mRNA full length insert cDN 46 _ _ 428227 AA321649 Hε 2248 εmall inducible cytokine εubfa ily B (Cy 46
20 430510 AW162916 Hε 241576 hypothetical protein PR02577 46
425804 BE501698 Hs 258189 ESTs 46 435347 AW014873 Hs 116963 ESTs 46 446002 AI346468 Hs 145789 ESTs 46 452883 X80031 Hs 150318 ESTs 46 25 442176 AA983764 Hs 128910 ESTs 46
443253 AI041212 Hs 132117 ESTs 45 419556 U29615 Hs 91093 chitinase 1 (chitotπosidase) 45 439920 H05430 Hs 144455 ESTs 45 421502 AF111856 Hs 105039 solute earner family 34 (sodium phospha 45 30 434424 AI811202 Hs 125365 Homo sapiens cDNA FLJ23523 fis, clone L 44
408625 AW243323 Hs 266785 ESTs 44 449299 AA299919 gb EST12592 Uteruε tumor I Homo sapiens 44 450656 AA010539 Hs 18912 ESTs 44 433815 AI696602 Hs 112757 ESTs 44 35 416879 H98899 Hs 42599 ESTs 43
432182 AW607789 Hs 293119 ESTs, Weakly similar to ALU7_HUMAN ALU S 43 445386 AI422005 Hs 160380 ESTε 43 450478 AW451709 Hs 271200 ESTε 43 453080 AI423056 Hε 23921 Homo sapiens cDNA FU12482 fis, clone NT 43 40 435496 AW840171 Hs 265398 ESTs, Weakly similar to transformation r 43
443257 AI334040 Hs 11614 Homo sapiens cDNA FLJ23555 fis, clone L 43 453921 AI824009 Hs 44577 ESTs 43 419721 NM.001650 Hs 288650 aquapoπn 4 42 432316 AW973235 Hs 293697 ESTs 42 45 435202 AI971313 Hs 170204 KIAA0551 protein 42
440320 AA879294 gb nw86e09 s1 NCI_CGAP.Pr12 Homo sapiens 42 438796 W67821 Hs 109590 genethoniπ 1 42 400269 42
447724 AW298375 Hs 24477 ESTs 41 50 446509 AF169693 Hs 132892 protocadhenn 20 41
451620 AW449888 Hs 257224 ESTs 41 451963 AI825440 Hs 224952 ESTs 41 456408 AI288348 Hs 23450 mRNA for FLJ00023 protein 41 _ _ 425895 AI269484 Hs 161427 zinc finger protein 215 41
55 447048 AW393080 Hs 228320 Homo sapiens cDNA FLJ23537 fis, clone L 41
454024 AA993527 Hs 16281 hypothetical protein FU23403 40 415929 AA724373 Hs 295306 ESTs, Highly similar to unnamed protein 40 426625 T78300 Hs 171409 serologically defined ∞lon cancer antig 40 - Λ 434334 AA912476 Hs 116750 Homo sapiens cDNA FU13221 fis, clone NT 40
60 437138 AI935622 Hs 271245 ESTs 40
455024 AW851309 gb IL3-CT0220 170200 067-C11 CT0220 Homo 40 436246 AW450963 Hs 119991 ESTs 40 416030 H15261 Hs 21948 ESTs 40 459267 AJ003631 gb AJ003631 Selxted chromosome 21 cDNA 39 65 445122 AW241632 Hs 147377 Homo sapiens cDNA FLJ23598 fis, clone L 39
414812 X72755 Hs 77367 monokine induced by gamma interferon 39 421160 AL080215 Hs 102301 Homo sapiens mRNA, cDNA DKFZp586J0323 (f 39 425734 AF056209 Hs 159396 peptidylglycme alpha-amidafing monooxyg 39 429208 AA447990 Hs 190478 ESTs 39 70 442957 AI949952 Hs 49397 ESTs 39
444050 AW138295 Hs 135024 ESTs 39 444078 BE246919 Hs 10290 U5 snRNP-specific 40 kDa protein (hPrpδ- 39 451024 AA442176 gb zw63b08 r1 Soaresjotal fetus_Nb2HF8_ 39 442832 AW206560 Hs 253569 ESTs 39 75 423377 AL049377 gb Homo sapiens mRNA cDNA DKFZp586H0718 39
451895 T93573 Hs 16970 ESTs 39 442353 BE379594 Hs 49136 ESTs 38 421464 AA291553 Hε 190086 ESTs 38 404043 38 80 407055 X89211 gb H sapiens DNA for endogenous retrovir 38
410008 AA079552 gb zm20h12 s1 Stratagene pancreas (93720 38 410247 AF181721 Hs 61345 RU2S 38 417461 R38403 Hs 13305 ESTs 38 423609 AA328348 Hs 218289 ESTs 38
440444 AA885221 Hs 156984 ESTs 38
446254 BE179829 Hs 179852 Homo εapiens cDNA FU12832 fis, clone NT 38
447505 AL049266 Hs 18724 Homo sapienε mRNA, cDNA DKFZp564F093 (fr 38
423244 AL039379 Hs 209602 ESTs, Weakly similar to ubiquitous TPR m 38
446921 AB012113 Hs 16530 small inducible cytokine subfamily A (Cy 38
444271 AW452569 Hs 149804 ESTs 38
434217 AW014795 Hs 23349 ESTs 38
452571 W31518 Hs 34665 ESTs 37
423575 C18863 Hs 163443 Homo sapiens cDNA FLJ11576 fis, clone HE 37
408771 AW732573 Hs 47584 potassium voltage-gated channel, delayed 37
431322 AW970622 gb EST382704 MAGE resequences MAGK Homo 37
445034 AW293376 Hs 160323 ESTs 37
438842 AA827176 Hs 124316 ESTs 37
424906 AI566086 Hs 153716 Homo sapiens mRNA for Hmob33 protein, 3 37
415025 AW207081 Hs 72307 ESTs 37
420313 AB023230 Hs 96427 KIAA1013 protein 37
423448 AK000776 Hs 128753 Homo sapiens cDNA FLJ20769 fis clone CO 37
433492 AW605849 gb MR0-HTO241-200100 006-g02 HT0241 Homo 37
434636 AA083764 Hs 241334 ESTs 37
435747 AI079519 Hs 134398 ESTs 37
458158 AW296778 Hs 300357 ESTs, Highly similarto dJ416F21 2 [H sa 37
419261 X07876 Hs 89791 wingless-type MMTV integration site fami 37
410060 NM.001448 Hs 58367 glypican 4 37
426116 AA868729 Hs 144694 ESTs 37
409203 AA780473 Hs 687 cytxhrome P450, subfamily IVB, polypept 37
414259 W44633 Hs 25044 Homo sapiens cDNA FLJ23131 fis, clone L 37
406671 AA129547 Hs 285754 met proto oncogene (hepatocyte growth fa 36
431889 AA521277 Hs 124946 ESTs 36
430414 AW365665 Hs 120388 ESTs 36
433426 H69125 Hs 133525 ESTs 36
421764 AI681535 Hs 99342 ESTs, Weakly similar to KCC1.HUMAN CALCI 36
410785 AW803341 gb IL2-UM0079-090300 050 D03 UM0079 Homo 36
455235 AW875951 gb CM1-PT0013-131299 067-109 PT0013 Homo 36
408399 NM 005426 Hs 44585 tumor protein p53 binding protein, 2 36
429784 M89796 Hs 30 membrane spanning 4-domaιns, εubfamily A 36
436982 AB018305 Hs 5378 εpondm 1, (f-spondin) extracellular mat 36
432231 AA339977 Hs 274127 CLST 11240 protein 36
432837 AA310693 Hs 279512 HSPC072 protein 36
452166 AI948607 Hs 264680 ESTs 35
458154 AW816379 gb QV4-ST0234-181199-035-g01 ST0234 Homo 35
420362 U79734 Hε 97206 huntingtm interacting protein 1 35
424202 BE350295 Hs 15032 ESTs, Weakly similar to RAN binding prot 35
410658 AW105231 Hε 192035 ESTs 35
415457 AW081710 Hs 7369 ESTs, Weakly similar to ALULHUMAN ALU S 35
419503 AA243642 Hs 137422 ESTs 35
439479 AI734258 Hs 245367 ESTs, Weakly similar to ALULHUMAN ALU S 35
448404 BE089973 gb RC6-BT0709 310300-021-G07 BT0709 Homo 35
424268 AA397653 Hs 144339 Human DNA sequence from clone 495010 on 35
420637 AW976153 gb EST388262 MAGE resequences, MAGN Homo 35
450715 AI266484 Hs 31570 ESTs, Weakly similar to KIAA1324 protein 35
428927 AA441837 Hs 90250 ESTs 35
422544 AB018259 Hs 118140 KIAA0716 gene product 34
431207 AA495925 Hs 9394 ESTs 34
424508 AL080103 Hε 149770 Homo sapiens cDNA FLJ13658 fis, clone PL 34
441484 AA935481 Hε 58972 ESTs 34
425916 NM 006786 Hs 162200 urotensin 2 34
401793 34
431169 AW971240 gb EST383329 MAGE resequences, MAGL Homo 34
438038 AI732629 Hs 194161 ESTs, Weakly similarto TA2R HUMAN, BETA 34
439619 AW975998 Hs 58595 ESTs 34
446577 AB040933 Hs 15420 KIAA1500 pratem 34
450445 AW974636 Hs 194563 ESTs 34
459482 AA625339 Hs 237052 EST, Weakly similar to ALU1 HUMAN ALU SU 34
445495 BE622641 Hs 38489 ESTs 34
428743 AL080060 Hs 301549 Homo sapiens mRNA, cDNA DKFZp564H172 (fr 34
426320 W47595 Hs 169300 i transforming growth fxtor, beta 2 34
432869 AW974094 gb EST386197 MAGE resequences, MAGM Homo 33
419235 AW470411 Hs 288433 I neurotπmin 33
429703 T93154 Hs 28705 ESTs 33
413499 BE144884 gb CM0 HT0182-041099 065-e11 HT0182 Homo 33
406182 33
417307 N99673 Hs 3585 ESTε, Weakly similar to AF126743 1 DNAJ 33
430140 AW296771 Hs 22199! ) ESTs 33
436111 AI803082 Hs 157212 ESTs 33
449729 R72032 Hs 29235 ESTs 33
457620 AA602711 gb np03h06 s1 NCI CGAP Pr2 Homo sapiens 33
428434 AW363590 Hs 65551 ESTs, Weakly similar to AF172993 1 PLUNC 33
406554 33
451381 BE241831 gb TCAAP2E0011 Pediatnc xute myelogeno 33
443113 AI040686 Hs 132908 ESTs 33
421470 R27496 Hs 1378 annexin A3 33
446428 AW082270 Hs 210617 ESTs, Weakly similar to ALU4 HUMAN ALU S 33 435031 AI632091 Hs 116877 ESTs 33
413136 BE066941 gb PMO BT0340-091299 002-a11 BT0340 Homo 32
429228 AI553633 Hs 104985 ESTs 32
420252 AW270404 Hs 193161 ESTs 32
423629 AW021173 Hs 18612 Homo sapienε cDNA FLJ21909 fiε, clone H 32
444339 T96555 Hs 31562 ESTs 32
434164 AW207019 Hs 148135 ESTs 32
404599 32
426920 AA393351 Hs 132121 ESTs 32
453736 AL118674 Hs 34871 KIAA0569 gene product 32
408923 H73881 Hs 255436 ESTs 32
430919 AA489041 Hs 295448 ESTs 32
431622 AW979271 Hs 293184 ESTs 32
433584 AW295399 gb UI H-BI2-ahv h-03-O-UI s1 NCI_CGAP.Su 32
437073 AI885608 Hs 94122 ESTs 32
438394 BE379623 Hs 27693 CGI-124 protein 32
446242 N66336 Hs 7360 ESTs 32
452542 AW812256 gb RCO ST0174-191099031-a07 ST0174 Homo 32
454009 AW015927 Hs 233071 ESTs 32
449765 N92293 Hs 206832 EST, Moderately similar to ALU8_HUMAN AL 32
415652 T79213 Hs 272073 ESTs 32
453931 AL121278 Hs 25144 ESTs 32
439382 BE247684 Hs 103070 ESTs 32
420077 AW512260 Hs 87767 ESTs 32
430437 AI768801 Hs 169943 Homo sapιens cDNA FLJ13569 fis, clone PL 32
446745 AW118189 Hε 156400 ESTs 3 1
408308 AL033377 Hs 44197 hypothetical protein DKFZp564D0462 3 1
450320 AW291775 Hs 213793 ESTs 31
429597 NM 003816 Hs 2442 a disintegnn and metalloprotemase doma 3 1
449523 NM_000579 Hs 54443 chemokine (C-C motif) receptor 5 3 1
451110 AI955040 Hs 301584 ESTs 3 1
431745 AW972448 Hε 163425 ESTs 31
410781 AI375672 Hs 165028 ESTs 31
419546 AA244199 gb nc06c05 s1 NCI CGAP Pr1 Homo sapiens 3 1
444330 AI597655 Hs 49265 ESTs 3 1
408761 AA057264 Hs 238936 ESTs 31
409026 AL137554 Hs 49927 Homo sapiens mRNA, cDNA DKFZp434H1720 (f 31
432055 AW972359 Hs 293334 ESTs 31
432441 AW292425 Hs 163484 ESTs 31
408045 AW138959 Hs 245123 ESTs 3 1
427191 BE221825 Hs 97691 ESTs 3 1
416965 N26223 Hs 160436 ESTs 31
441594 AL041080 Hs 208765 ESTs 31
406992 S82472 gb beta -pol=DNA polymerase beta {exon a 30
431941 AK000106 Hs 272227 Homo sapienε cDNA FLJ20099 fiε, clone CO 30
438323 AI985394 Hε 123369 ESTs 30
427698 AW972594 Hs 294140 ESTs 30
424296 AI631874 Hs 169391 ESTs 30
450522 A1698839 gb wd31f02 x1 Soares_NFL_T_GBC_S1 Homo s 30
407942 AA378608 Hε 5894 hypothetical protein FU 10305 30
417991 AA731452 Hε 190008 ESTs 30
422589 AA312735 Hs 179725 ESTs 30
437583 AA761190 Hs 244627 ESTs 30
452019 AL157503 Hs 27552 Homo εapiens mRNA, cDNA DKFZp586N2424 (f 30
449494 AW237014 Hε 288650 aquapoπn 4 30
444188 AI393165 Hε 19175 ESTs 30
400297 AI127076 Hs 288381 hypothetical protein DKFZp56401278 30
410811 AW805687 Hs 300648 ESTs 30
450584 AA040403 Hs 60371 ESTs 30
428043 T92248 Hs 2240 uteroglobin 30
436120 AI248193 Hs 119860 ESTs 30
442324 R63578 Hs 28426 ESTε 29
448693 AW004854 Hε 228320 Homo sapiens cDNA FLJ23537 fis, clone L 29
425555 AA359291 Hs 130767 Homo sapienε cDNA FLJ23553 fis, clone L 29
431385 BE178536 Hs 11090 high affinity immunoglobulin epsilon rx 29
408427 AW194270 Hε 177236 ESTε 29
459587 AA031956 gb zk15e04 ε1 Soareε_pregnanLuterus_NbH 29
438128 AA904430 Hε 122049 ESTε, Weakly εimilar to U4/U6 small nucl 29
408938 AA059013 Hs 22607 ESTs 29
419276 BE165909 Hs 134682 Homo sapiens cDNA FLJ23161 fis, clone L 29
422022 AA302420 Hs 200442 ESTε 29
426890 AA393167 Hs 41294 ESTs 29
427374 AI150033 Hs 143686 ESTs 29
434208 T92641 Hs 127648 hypothetical protein PR02176 29
446466 H38026 Hs 308 arrest 3, retinal (X arrestin) 29
451229 AW967707 Hs 48473 ESTs 29
415511 AI732617 Hs 182362 ESTs 29
408776 AA057365 Hs 63356 ESTs 29
421110 AJ250717 Hs 1355 cathepsin E 29
453636 R67837 Hs 169872 ESTs 29
436578 AI091435 Hs 134859 ESTs 29
426083 AW962712 Hs 126712 ESTs, Weakly similar to AF191020 1 E21G5 29
419231 AL046294 Hs 136245 ESTs Weakly similarto dJ202l21 4 [H sa 28 408171 AA301228 Hs 43299 Homo sapiens cDNA FLJ12890 fis clone NT 28
445189 AI936450 Hs 147482 ESTs 28
419150 T29618 Hs 89640 TEK tyrosine kinase, endothelial (venous 28
427457 AW779105 Hs 164682 ESTs, Weakly similar to ORF2 conseπsuε s 28
435082 AA664273 Hs 186104 Homo sapiens cDNA FLJ13803 fis, clone TH 2 8
446932 AA961459 Hs 125644 ESTs 28
439140 W85737 Hs 290830 ESTs 2 8
405041 28
421306 AA806207 Hs 125889 ESTs 28
427514 AA640773 Hs 209224 ESTs 28
427939 T92459 Hs 16886 ESTs 28
429127 AA749382 Hs 107233 ESTs 28
429590 AI219490 Hs 44445 ESTs, Weakly similar to Kelch motif cont 28
433163 R40468 Hs 163582 ESTs 28
439635 AA477288 Hs 94891 Homo sapiens cDNA FLJ22729 fis, clone H 2 8
448015 AI458065 Hs 23196 ESTs 28
456761 D59899 Hs 127842 CGI-142 28
457112 AW772449 Hs 268081 ESTs, Weakly similar to ALU1.HUMAN ALU S 2 8
449540 AA001713 gb zh86e08 s1 Soares.fetal.liver.spleen. 28
447020 T27308 Hs 16986 hypothetical protein FLJ11046 28
412610 X90908 Hs 74126 fatty xid binding protein 6, ileal (gas 28
433515 AA595800 Hs 190246 ESTs 28
424450 AL137526 Hs 147472 dynein intermediate chain 2 2 8
438122 AI620270 Hs 129837 ESTs 28
424086 AI351010 Hs 102267 lysyl oxidase 28
438885 AI886558 Hs 184987 ESTs 28
412903 BE007967 Hs 155795 ESTs 28
454111 AW081681 Hs 269064 ESTs 2 8
439398 AA284267 Hs 221504 ESTs 28
449802 AW901804 Hs 23984 hypothetical protein FLJ20147 28
434812 AA649860 Hs 189496 ESTs 28
432583 AW023624 Hs 162282 ESTs 28
428104 AA421350 Hs 191604 ESTs 28
408217 AI433201 Hs 279860 hypothetical protein FLJ20030 28
438016 AI949638 Hs 109150 SH3-domaιπ binding protein 5 (BTK-asεoci 2 8
436396 AI683487 Hs 299112 Homo sapiens cDNA FLJ11441 fis, clone HE 27
430887 N66801 Hs 260287 ESTs, Weakly similar to ALU7 HUMAN ALU S 27
446311 AW007294 Hs 149795 ESTs, Weakly similar to ALULHUMAN ALU S 27
416185 AW975861 Hs 291995 ESTs 27
408613 AW242086 Hs 253967 ESTs 27
442510 AF150179 Hs 249890 ESTs 27
433293 AF007835 Hs 32417 ESTs 27
413875 BE176776 gb RC3 HT0586-110300-011-g09 HT0586 Homo 27
404488 27
408936 AL138043 Hs 293549 ESTε 27
431980 AA523696 Hs 222695 Homo sapiens cDNA FLJ20986 fis, clone C 27
436738 AW102613 Hs 152913 ESTε 27
451797 AW663858 Hs 56120 ESTs 27
452163 AI863140 gb tz43h12 x1 NCI_CGAP_Brn52 Homo sapien 27
452778 R71338 Hs 5921 Homo εapiens cDNA FLJ21592 fis, clone C 27
459366 AA129703 gb zn92b05 r1 Stratagene lung carcinoma 27
431448 AL137517 Hs 288381 hypothetical protein DKFZp56401278 27
430733 AW975920 Hs 283361 ESTs 27
453652 AW009640 Hs 28368 ESTs 27
453616 NM.003462 Hs 33846 dynein, axonemal, light intermediate pol 27
411905 BE265067 gb 601193893F1 NIH MGC 7 Homo εapienε cD 27
408729 AA195764 Hs 72639 ESTε 27
450726 AW204600 Hs 264330 N-xylsphingosme amidohydrolase (xid c 27
447720 AL038765 Hs 161304 ESTs 27
451497 H83294 Hs 284122 Wnt inhibitory factor-1 27
442074 C17511 Hs 128430 ESTs 27
424115 AA335497 Hs 293965 ESTs 27
417728 AW138437 Hs 24790 KIAA1573 protein 27
433803 AI823593 Hs 27688 ESTs 27
419247 S65791 Hs 89764 fragile X mental retardation 1 27
424310 AA338648 Hs 50334 ESTs 26
438504 AW665281 Hs 224625 ESTs 26
426486 BE178285 Hs 170056 Homo sapienε mRNA, cDNA DKFZp586B0220 (f 26
430417 AA461045 Hs 50701 ESTs 26
438297 AW515196 Hs 258238 ESTs, Moderately similar to ALU1 HUMAN A 26
422505 AL120862 Hs 124165 ESTs 26
457285 AI038858 Hs 228780 ESTs, Highly similar to AF199597 1 A-typ 26
428667 AI375550 Hs 74407 nucleolar protein p40, homolog of yeast 26
431750 AA514986 Hs 283705 ESTs 26
435575 AF213457 Hs 44234 tπggenng rxeptor expresεed on myeloid 26
413385 M34455 Hs 840 indoleamme pyrrole 2,3 dioxygenase 26
403903 26
407910 AA650274 Hs 41296 fibronxtin leucine πch tranεmembrane p 26
423424 AF150241 Hs 128433 1 prostaglandm D2 synthase, hematopoietic 26
436043 AW963838 Hs 16883C 1 Homo sapiens cDNA FLJ12136 fis, clone MA 26
436645 AW023424 Hs 15652C I ESTs 26
408380 AF123050 Hs 44532 diubiquit 26
402629 26 406594 26
415122 D60708 Hs 22245 ESTs 26
416747 AW876523 Hs 15929 Homo sapiens cDNA FLJ12910 fis, clone NT 26
420159 AI572490 Hs 99785 Homo sapiens cDNA FLJ21245 fis clone C 26
444361 W76027 Hs 23920 Homo sapiens cDNA FU13124 fis, clone NT 26
446609 BE395090 Hs 15535 Human gene from PAC 886K2 chromosome 1 26
449260 AA741180 Hs 29879 ESTs 26
452311 AW304029 Hs 252744 ' ESTs 26
413802 AW964490 Hs 32241 ESTs 26
417318 AW953937 Hs 12891 ESTs 26
440028 AW473675 Hs 125843 ESTs 26
437960 AI669586 Hs 222194 ESTs 26
433687 AA743991 gb ny57g01 s1 NCI_CGAP_Pr18 Homo sapiens 26
430573 AA744550 Hs 136345 ESTs 26
439737 AI751438 Hs 41271 Homo sapiens mRNA full length insert cDN 26
453204 R10799 Hs 191990 ESTs 26
436751 AA732217 Hs 294054 ESTs 26
408165 AL137573 Hs 43143 Homo sapiens mRNA, cDNA DKFZp564A2463 (f 26
431120 AA492588 gb ng99c08 s1 NCI CGAP Thy1 Homo εapienε 25
446638 AL133063 Hs 15783 Homo εapieπs mRNA, cDNA DKFZp434P1115 (f 25
438458 AW975186 Hs 162875 ESTs, Weakly similar to ALU1 HUMAN ALU S 25
446063 AI720140 Hs 151079 ESTs 25
430499 AW969408 Hs 231991 ESTs 25
450496 AW449251 Hs 257131 ESTs 25
441330 AI692984 Hs 129354 ESTs 25
424433 H04607 Hs 9218 ESTs 25
434677 AW444575 Hs 130834 ESTs 25
445779 AI253104 Hs 189267 ESTs 25
444649 AW207523 Hs 197628 ESTs 25
415451 H19415 Hs 268720 ESTs, Moderately similar to ALULHUMAN A 25
432222 AI204995 gb aπ03c03 x1 Stratagene schizo brain S1 25
404288 25
408572 AA055611 Hs 226568 ESTs, Moderately similar to ALU4_HUMAN A 25
408727 AL137259 Hs 47115 hypothetical protein DKFZp434D0513 25
408728 AL137379 Hs 47125 hypothetical protein FLJ13912 25
410095 AW589638 Hs 258947 ESTs 25
410947 AK000305 Hs 67055 hypothetical protein FLJ20298 25
418343 AA216372 Hs 159501 ESTs 25
423401 NM 001992 Hs 128087 coagulation factor II (thrombin) rxepto 25
428637 AW979268 gb EST391378 MAGE resequences, MAGP Homo 25
429846 AB023021 Hs 225945 fijcosyltransferase 9 (alpha (1,3) fucosy 25
432507 BE391093 gb 601286042F1 NIH.MGC.44 Homo sapiens c 25
433858 N69243 Hs 192974 Homo sapienε cDNA FU12735 fis, clone NT 25
438651 H64500 Hs 123646 ESTs 25
443830 AI142095 Hs 143273 ESTs 25
446800 AI341635 Hs 156486 ESTs 25
450262 AW409872 Hs 271166 ESTs, Moderately similar to ALU7.HUMAN A 25
451343 AW975057 Hs 293353 ESTs 25
451539 AA059467 Hs 218933 ESTs 25
452412 AA029608 Hs 61373 ESTs 25
454288 BE222648 Hs 279458 ESTs, Highly similar to C380A1 1b [H sap 25
445745 AB007924 Hs 13245 KIAA0455 gene product 25
424943 AU077260 Hs 153924 death-asεxiated protein kinaεe 1 25
440106 AA864968 Hs 127699 KIAA1603 protein 25
458429 AV646559 Hs 12346 Homo εapienε cDNA FU21399 fiε, clone C 25
415261 T40928 Hs8346 ESTs 25
420026 AI831190 Hs 166676 ESTs 25
431806 AF186114 Hs 270737 tumor nxrosis factor (ligand) superfami 25
458722 AA741545 Hs 282832 ESTs 25
419449 H18417 Hs 57483 Homo sapienε cDNA FLJ14294 fis, clone PL 25
436260 BE172762 Hs 292710 ESTs, Weakly similar to ALU5 HUMAN ALU S 25
433644 AW342028 Hs 256112 ESTs 25
419172 AW338625 Hs 22120 ESTs 25
437982 N93466 Hs 121764 ESTs, Weakly similar to testicular tekti 25
443348 AW873596 Hs 57572 ESTs 25
417218 AA005247 Hs 285754 met proto-oncogene (hepatxyte growth fa 25
419236 AA330447 Hs 135159 Homo sapiens cDNA FU11481 fis, clone HE 25
448030 N30714 Hs 20161 HDCME31P protein 25
417203 AA406341 Hs 269908 Homo sapiens cDNA FLJ11991 fis, clone HE 25
449275 AW450848 Hs 205457 KIAA1620 protein 24
436198 AK001125 Hs 300922 Homo sapiens cDNA FU10263 fis, clone HE 24
452281 T93500 Hs 28792 Homo sapiens cDNA FLJ11041 fis, clone PL 24
442191 W95186 Hs 8136 endothelial PAS domain protein 1 24
428571 NM 006531 Hs 2291 Probe hTg737 (polycystic kidney disease, 24
453142 AA033648 Hs 7473 ESTs 24
425657 T89839 Hs 119471 ESTs 24
452822 X85689 Hs 288617 Homo sapiens cDNA FU22621 fis, clone H 24
416778 M16505 Hs 79876 steroid sulfatase (microsomal), arylsulf 24
458332 AI000341 Hs 220491 ESTs 24
448140 AF146761 Hs 20450 BCM like membrane protein precursor 24
459644 24
429125 AA446854 Hs 271004 I ESTs 24
448337 AW206453 Hs 3782 ESTs 24 427778 AA412323 Hs 105323 ESTs 24
425371 D49441 Hs 155981 mesothelin 24
448299 AA497044 Hs 20887 hypothetical protein FLJ10392 24
447610 AW296286 Hs 255534 ESTs 24
409519 AA075368 gb zm86h10 r1 Stratagene ovarian cancer 24
441006 AW605267 HS 7627 CGI-60 protein 24
440817 AI341423 Hs 270165 ESTs 24
420020 BE295866 Hs 94382 adenosme kinase 24
435395 AA729235 Hs 117907 ESTs 24
424144 AA454033 Hs 41644 Homo sapiens cDNA FLJ23003 fis, clone L 24
405494 24
458145 AI239457 Hs 130794 ESTs 24
408547 AA574291 Hs 57837 ESTs 24
408941 AI452469 Hs 165221 ESTs 24
409457 AW818081 gb CM4-ST0276-101299 059-b09 ST0276 Homo 24
417137 U46265 Hs 81281 hypothetical protein 24
418950 T78517 Hs 13941 ESTs 24
420756 AA411800 Hs 189900 ESTs 24
428316 AI860775 Hs 98506 ESTs 24
432896 NM 014097 Hs 279778 PR01693 protein 24
436148 BE005252 gb CM1-BN0116 030400 171 g02 BN0116 Homo 24
436284 AA708016 Hs 190389 ESTs 24
437327 AL353942 gb Homo sapiens mRNA, cDNA DKFZp761L2312 24
442611 BE077155 Hs 177537 ESTs 24
456062 AI866286 Hs 71962 ESTs 24
433014 NM 014711 Hs 279912 KIAA0419 gene product 24
401335 24
428771 AB028992 Hs 193143 KIAA1069 protein 24
419140 AI982647 Hs 215725 ESTs 24
454693 AW813428 gb MR3-ST0192-010200-210-C05 ST0192 Homo 24
427785 X81053 Hs 180828 collagen, type IV, alpha 4 24
407339 AA777542 Hs 132670 ESTs 24
408369 R38438 Hs 182575 solute camerfamily 15 (H+/peptιde tra 24
427019 AA001732 Hs 173233 hypothetical protein FLJ10970 24
431089 BE041395 Hs 283676 ESTs, Weakly similar to unknown protein 24
452561 AI692181 Hs 49169 KIAA1634 protein 24
427878 C05766 Hs 181022 CGI-07 protein 24
419752 AA249573 Hs 152618 ESTs 24
430073 U86136 Hs 232070 telomerase associated protein 1 24
452401 NM.007115 Hs 29352 tumor necrosis fxtor, alpha induced pro 24
430345 AK000282 Hs 239681 hypothetical protein FU20275 23
407905 AW103655 Hs 252905 ESTs 23
427660 AI741320 Hs 114121 Homo sapiens cDNA FU23228 fis, clone C 23
422355 AW403724 Hs 140 immunoglobulin heavy constant gamma 3 (G 23
453049 BE537217 Hs 30343 ESTs 23
438568 R98865 Hs 11135 major histocompatibility complex, class 2 3
453445 AL036532 Hs 91453 ESTs 23
424711 NM 005795 Hs 152175 calcitonin receptor-like 23
446346 AI290205 gb ql79g06 x1 Soares NhHMPu S1 Homo sapi 23
441974 AI683782 Hs 128245 ESTs 23
444805 AB007899 Hs 12017 KIAA0439 protein, homolog of yeast ubiqu 23
424027 AW337575 Hs 201591 ESTs 2 3
419606 AW294795 Hs 198529 ESTs, Weakly similar to similar to acyl- 23
428613 AB037749 Hs 186928 KIAA1328 protein 23
434340 AI193043 Hs 128685 ESTs 23
450297 AW901347 Hs 38592 Homo sapiens cDNA FLJ23342 fis, clone H 23
432779 AW979241 gb EST391351 MAGE resequences, MAGP Homo 23
433650 AA603472 Hs 28456 ESTs 23
419086 NM 000216 Hs 89591 Kallmann syndrome 1 sequence 23
428758 AA433988 Hs 98502 Homo sapiens cDNA FU14303 fis, clone PL 23
430153 AW968128 gb EST380338 MAGE resequences MAGJ Homo 23
418883 BE387036 Hs 1211 xid phosphataεe 5, tartrate resistant 23
427669 AW451832 Hs 255938 ESTs, Moderately similarto KIAA1200 pro 23
400610 23
402222 23
407162 N63855 Hs 142634 zinc finger protein 23
415250 F02614 Hs 27319 ESTs 23
421751 AW813731 Hs 159153 ESTs 23
428552 AW274560 Hs 129520 ESTs 23
432658 AW973769 Hs 162319 ESTs 23
434742 AA648302 Hs 291695 . ESTs 23
436586 AI308862 Hs 167028 ! ESTs 23
441675 AI914329 Hs 5461 ESTs 23
442039 AW276240 Hs 128355 ! ESTs, Weakly similar to p80 [R norvegicu 23
443160 AI467915 Hs 36053 ESTs 23
448764 AI568607 Hs 18211; ! ESTs 23
449579 AW207260 Hs 13401^ 1 prostate cancer assxiated protein 6 23
439810 AL109710 Hs 85568 EST 23
413714 AI560944 Hs 71428 ESTs 23
400289 X07820 Hs 2258 matnx metalloprotemase 10 (stromelysin 23
413384 NM.000401 Hs 75334 exostoses (multiple) 2 23
438670 AI275803 Hs 123428 ESTs 23
419991 AJ000098 Hs 94210 eyes absent (Drosophila) homolog 1 23 459702 23
414888 AL039185 Hs 77558 thyroid hormone receptor mteractor 7 23
438474 AW865818 Hs 6232 KIAA0764 gene product 23
453037 AA045175 Hs 177552 ESTs 23
428467 AK002121 Hs 184465 hypothetical protein FLJ11259 23
413930 M86153 Hs 75618 RAB11 A, member RAS oncogene family 23
422429 AA310527 gb EST181333 Jurkat T-cells V Homo sapie 23
415083 AI632683 Hs 27179 Homo εapiens cDNA FLJ12933 fis, clone NT 23
417015 M83772 Hs 80876 flavin containing monooxygenase 3 23
406506 23
448330 AL036449 Hs 207163 ESTs 23
409719 AI769160 Hs 108681 ESTs 23
423354 AB011130 Hs 127436 calcium channel, voltage-dependent, alph 23
425188 AK002052 Hs 155071 hypothetical protein FLJ11190 23
427961 AW293165 Hs 143134 ESTs 23
447357 AI375922 Hs 158367 ESTs 23
412642 BE244598 Hs 809 hepatxyte growth factor (hepapoietm A, 23
453716 AA037675 Hs 152675 ESTs 23
437370 AL359567 Hs 161962 Homo sapiens mRNA, cDNA DKFZp547D023 (fr 23
407949 W21874 Hs 247057 ESTs 22
427972 AA864870 Hs 181304 putative gene product 22
453313 BE005771 Hs 153746 Homo sapiens cDNA FU22490 fis, clone H 22
426476 NM 003296 Hs 2042 testis spxific protein 1 (probe H4-1 p3 22
424238 AA337401 Hs 137635 ESTs 22
452930 AW195285 Hs 194097 ESTs 22
424527 AW138558 Hs 267158 ESTs 22
453095 AW295660 Hs 252756 ESTs 22
449161 N53431 Hs 47647 ESTs, Weakly similar to KIAA0423 [H sapi 22
429586 T73510 Hs 209153 angiopoietin-like 3 22
423782 AI472209 Hs 288369 ESTs 22
458124 AW005548 Hs 124590 ESTs 22
450109 AI539295 Hs 17967 ESTs 22
421461 AW291023 Hs 97255 ESTs 22
412222 AA528283 Hs 292737 ESTs 22
418882 NM.004996 Hs 89433 ATP-binding cassette, sub-family C (CFTR 22
441736 AW292779 Hs 169799 ESTs 22
401049 22
440727 AI073991 Hs 134268 ESTs 22
419751 AW195581 Hs 93121 KIAA0761 protein 22
445640 AW969626 Hs 31704 ESTs Weakly similar to KIAA0227 [H sapi 22
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 22
422109 S73265 Hs 1473 gastππ-releasing peptide 22
410292 AA843087 Hs 124194 ESTε 22
434265 AA846811 Hs 130554 Homo sapiens cDNA FLJ23089 fis, clone L 22
449695 AA164569 Hs 34550 ESTs 22
429399 AA452244 Hs 16727 ESTs 22
444042 NM 004915 Hs 10237 ATP-binding cassette, sub-family G (WHIT 22
432343 NM.002960 Hs 2961 S100 calcium binding protein A3 22
436772 AW975688 Hε 250867 zona pellucida glycoprotein 3A (sperm re 22
428784 Y12851 Hs 193470 puπnergic rxeptor P2X, ligand-gated to 22
445268 AI218358 Hs 175048 ESTs 22
402481 22
412608 AA247995 Hs 44898 Homo sapienε clone TCCCTA00151 mRNA εequ 22
416521 H60929 Hs 44197 hypothetical protein DKFZp564D0462 22
416624 H69044 gb yr77h05 s1 Soares fetal liver spleen 22
419780 AA713522 Hε 87752 ESTs 22
421211 AA284966 Hs 266308 ESTs, Weakly similar to AF216312 1 type 22
427541 AI798983 Hs 97961 ESTs 22
432013 AI796879 Hs 162102 ESTs 22
436461 AW511956 Hε 293261 ESTs 22
438002 AI560246 Hs 201648 ESTs, Weakly similar to ZN42 HUMAN ZINC 22
440312 AW614597 Hs 72475 ESTs 22
440479 AA886461 Hs 208161 ESTs 22
441178 W90789 Hs 153976 ESTs 22
441235 AI884586 Hs 135570 Homo sapiens cDNA FLJ21268 fis, clone C 22
443314 AW771701 Hs 54646 ESTs 22
422165 AL041199 Hs 1481 histidine dxarboxylase 22
450696 AI654223 Hε 16026 Homo sapiens cDNA FU23191 fis, clone L 22
432974 BE348793 gb ht70g02 x1 NCI_CGAP_Lu24 Homo εapiens 22
404200 22
435990 AI015862 Hε 131793 ESTs 22
421309 AI222086 Hs 270449 ESTs, Moderately similar to ALULHUMAN A 22
451558 NM 001089 Hs 26630 ATP-binding cassette, sub-family A (ABC1 22
416642 T96118 Hs 226313 ESTs, Weakly similar to ALULHUMAN ALU S 22
406672 M26041 Hs 198253 major histocompatibility complex, class 22
417819 AI253112 Hs 133540 ESTs 22
417355 D13168 Hs 82002 endothelin receptor type B 22
459574 AI741122 Hs 101810 Homo sapiens cDNA FLJ 14232 fis, clone NT 22
404274 22
415086 AI597963 Hs 118726 ESTs 22
418210 R54575 Hs 13337 ESTε, Weakly similar to unnamed protein 22
419220 AA811938 Hs 291759 ESTs 22
444314 AI140497 gb ow76b09 s1 Soaresjetal.liver.spleen. 22 451050 AW937420 Hs 69662 ESTs 22
417412 X16896 Hs 82112 interleukin 1 rxeptor, type I 22
428414 AL049980 Hs 184216 DKFZP564C152 protein 22
412925 AI089319 Hs 179243 ESTs 22
438192 AI859065 Hs 16808 ESTs Weakly similar to paraplegin like 22
410976 R36207 Hs 25092 ESTs 22
406673 M34996 Hs 198253 major hislocompatibility complex, class 22
448677 AA002071 gb zh85d01 s1 Soares_fetal liver.spleeπ 22
449321 AA001150 Hs 132937 ESTε 22
418557 BE140602 Hs 246645 ESTs 22
416320 H47867 Hs 34024 ESTs 22
426384 AI472078 gb tj85h03 x1 Soares NSF F8 9W OT PA P S 22
414140 AA281279 Hs 23317 ESTs 22
419520 AB009303 Hs 297790 Human clone 23734 mRNA sequence 22
446999 AA151520 Hs 279525 hypothetical protein PRO2605 22
457447 X78261 Hs 272177 H sapiens mRNA for TRE175' extremity an 22
451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 21
407366 AF026942 gb Homo sapiens cιg33 mRNA partial εequ 21
410048 W76467 Hε 274550 proline oxidase homolog 21
400880 21
418092 R45154 Hs 106604 ESTs 2 1
428780 AI478578 Hs 50636 ESTs 21
431067 AW574823 Hs 200413 ESTs 21
432803 AA565388 gb πk41f01 s1 NCI CGAP GC2 Homo sapiens 2 1
412104 AW205197 Hs 240951 ESTs 2 1
422819 AL122084 Hs 121073 hypothetical protein FU10466 21
454359 N71277 gb za36e03 ε1 Soareε fetal liver εpleen 2 1
424806 AA382523 Hs 105689 ESTs 21
434445 AI349306 Hε 11782 ESTs 21
442994 AI026718 Hs 16954 ESTs 21
410371 AA084482 Hs 115850 ESTs 21
450232 BE300815 Hs 201326 ESTs 21
417924 AU077231 Hs 82932 cyclin D1 (PRAD1 parathyroid adenomatos 2 1
430899 BE018217 Hs 183528 ESTs, Weakly similar to Bem46 like prote 21
431814 BE256242 Hs 270847 delta-tubulm 2 1
417543 AA203620 Hs 110153 ESTs, Weakly similar to BCGF.HUMAN B CEL 21
444542 AI161293 Hs 146862 ESTs Weakly similar to KIAA0525 protein 2 1
404593 21
434803 AW974640 gb EST386744 MAGE resequences, MAGM Homo 21
451623 H77818 Hs 268991 ESTs 21
452466 N84635 Hs 29664 Human DNA sequence from clone 682J15 on 21
402046 21
434927 H46612 Hs 293815 Homo sapiens HSPC285 mRNA, partial eds 21
436192 W93847 Hs 24139 Homo εapiens cDNA FLJ23137 fis, clone L 2 1
401987 21
423119 AA322201 Hs 131976 EST 21
427112 Z32887 Hs 290951 ESTs 21
414464 AI870175 Hs 13957 ESTs 2 1
447829 AI433029 Hs 164104 ESTs 21
449679 AI823951 Hs 296668 Homo sapiens cDNA FU11846 fis, clone HE 21
405472 21
413621 AI808648 Hs 184156 ESTs 21
432212 AW137742 Hs 293451 ESTs 21
404289 21
415362 F06735 gb HSC1JB091 normalized infant brain cDN 21
427739 AW196755 Hs 98105 ESTs 21
427772 AA412289 Hs 98123 ESTs 21
430844 T94960 gb ye38d07 r1 Stratagene lung (937210) H 21
434335 AA630107 Hs 213220 ESTs 21
436052 AI021983 Hs 271432 ESTε 21
442773 AB037722 Hs 8707 Homo sapiens mRNA, cDNA DKFZp434N1131 (f 21
446799 AW978373 Hs 49221 ESTs, Weakly similar to zinc finger prot 21
450221 AA328102 Hs 24641 cytoskeleton assxiated protein 2 21
455673 BE065939 gb RC3-BT0319-100100-012-c11 BT0319 Homo 21
458624 AI362790 Hs 181801 ESTs 21
405095 21
447207 AA442233 Hs 17731 hypothetical protein FU12892 21
433589 AA886530 Hs 188912 ESTs 2 1
438398 AA806526 Hs 130277 ESTs 21
447233 AW246333 Hs 17901 Homo sapiens cDNA FU21974 fis, clone H 21
447197 R36075 gb yh88b01 s1 Soares placenta Nb2HP Homo 21
431087 H12723 Hε 290791 ESTs 21
409064 AA062954 Hs 141883 ESTs 21
427558 D49493 Hε 2171 growth differentiation factor 10 21
426457 AW894667 Hs 169965 chimeπn (chimaeπn) 1 21
438118 AW753311 Hs 259415 ESTs 21
427621 BE621182 Hs 179882 Homo sapiens cDNA FLJ12437 fis clone NT 21
452114 N22687 Hs 8236 ESTs 21
448782 AL050295 Hs 301550 KIAA0758 protein 21
403937 21
416402 NM.000715 Hs 1012 complement component 4-bιndιng protein 2 1
452416 AA026115 Hs 114777 ESTs 21
451609 AL046019 Hs 209276 ESTs 2 1 435934 R19382 Hs 117869 ESTs 2 1
445158 A1992108 Hs 127206 ESTs 21
407930 AA045847 Hs 188361 Homo sapiens cDNA FLJ 12807 fis, clone NT 2 1
439335 AA742697 Hs 62492 ESTs, Weakly similar to S59856 collagen 2 1
443949 AW827419 Hs 235070 ESTs 2 1
429716 R25685 Hs 211933 collagen type XIII, alpha 1 21
415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t 2 1
438676 AA813745 Hs 123446 ESTs 2 1
405848 2 1
416940 N75620 Hs 43157 ESTs 21
442381 AI185136 Hs 48650 ESTε 2 1
420036 R60336 Hs 52792 Homo sapiens mRNA, cDNA DKFZp586H823 (f 2 1
436252 AI539519 Hs 120969 Homo sapiens cDNA FLJ11562 fis, clone HE 2 1
413450 Z99716 Hs 75372 N acetylgalactosaminidase, alpha- 21
426572 AB037783 Hs 170623 hypothetical protein FLJ11183 21
439425 AF086244 Hs 114659 ESTs 21
421168 AF182277 Hs 1360 cytxhrome P450, subfamily IIB (phenobar 2 1
449611 AI970394 Hs 197075 ESTs 21
404548 2 1
416734 H81213 Hs 14825 ESTs 2 1
435865 AA883552 Hs 16810 ESTs 2 1
439072 AF085930 Hs 269123 ESTs 21
447482 AB033059 Hs 18705 KIAA1233 protein 2 1
457292 AI921270 Hs 214178 Homo sapiens cDNA FLJ14251 fis, clone OV 2 1
444974 AI203500 Hs 151612 ESTs 2 1
456034 AW450979 gb Ul-H BI3-ala a 12-0-UI s1 NCI CGAP Su 21
430634 AI860651 Hs 26685 ESTs 2 1
426782 R14614 Hs 191254 ESTs 20
452943 BE247449 Hs 31082 hypothetical protein FLJ10525 20
445326 AI220072 Hε 165893 ESTs 20
421247 BE391727 Hs 102910 general transcription fxtor HH, polype 20
409994 D86864 Hs 57735 acetyl LDL receptor, SREC 20
443268 AI800271 Hs 129445 hypothetical protein FLJ12496 20
455226 AW902103 gb QV0 NN1022-120500-220-C07 NN1022 Homo 20
417321 N68722 Hs 191368 ESTs 20
423778 Y09267 Hs 132821 flavin containing monooxygenase 2 20
404323 20
448133 AA723157 Hs 73769 folate rxeptor 1 (adult) 20
421047 AW514772 Hs 104473 ESTs 20
425497 AA524596 Hs 188844 ESTs 20
444623 AI183829 Hs 202111 ESTs 20
412303 AW936336 gb QV4-DT0021-281299-070 g11 DT0021 Homo 20
433563 AI732637 Hs 277901 ESTε 20
406485 20
428330 L22524 Hs 2256 matrix metalloprotemase 7 (matπlysin, 20
455807 BE141140 gb MR0-HT0075-021299006-.07 HT0075 Homo 20
425465 L18964 Hs 1904 protein kinase C, iota 20
449424 AW448937 Hs 197030 ESTs 20
427940 AA417812 Hs 38775 ESTs 20
411502 AW946605 Hs 250154 Homo sapiens cDNA FLJ12973 fis, clone NT 20
411365 M76477 Hs 278242 tubulin, alpha, ubiquitous 20
412369 H80456 Hs 285243 Homo sapiens cDNA FU22029 fis, clone H 20
452959 AI933416 Hs 189674 ESTs 20
416580 T61572 Hs 79385 Human clone 23574 mRNA εequence 20
428775 AA434579 Hε 143691 ESTε 20
420000 AB036063 Hε 180726 Homo εapiens cDNA FLJ13543 fis, clone PL 20
408321 AW405882 Hs 44205 cortistatm 20
410011 AB020641 Hs 57856 PFTAIRE protein kmase 1 20
411050 AW814902 gb MR1 -ST0206-120400-022-f08 ST0206 Homo 20
452453 AI902519 gb QV-BT009-101198 051 BT009 Homo sapien 20
428978 AA442784 Hs 125445 ESTs 20
458562 N34128 Hs 145268 ESTs 20
425527 AL162032 Hs 158258 Homo sapiens mRNA, cDNA DKFZp434B1272 (f 20
403760 20
424368 AB037766 Hs 146085 KIAA1345 protein 20
421229 AI056590 Hs 7086 Homo sapiens cDNA FU23000 fis, clone L 20
436304 AA339622 Hs 108887 ESTs 20
453498 BE181412 Hs 23245 Homo sapienε cDNA FU11767 fiε, clone HE 20
439018 AW300887 Hs 26638 ESTs, Weakly similar to unnamed protein 20
453280 AL157476 Hs 32913 Homo sapieπε mRNA, cDNA DKFZp761C082 (fr 20
420193 AI460080 Hs 20286S l ESTε 20
444610 AI174783 gb HA2501 Human fetal liver cDNA library 20
401575 20
419092 J05581 Hs 89603 mucin 1, transmembrane 20
430129 BE301708 Hs 23395E > hypothetical protein FU20401 20
410763 AF279145 Hs 8966 tumor endothelial marker 8 20
414783 AW069569 Hs 75839 zinc finger protein 6 (CMPX1 ) 20
411492 T46848 Hs 70337 immunoglobulin superfamily, member 4 20
405963 20
418378 AW962081 gb EST374154 MAGE resequenceε, MAGG Homo 20
420831 AA280824 Hs 190035 ESTs 20
424152 AL133591 Hs 301405 Homo sapiens mRNA, cDNA DKFZp434N079 (fr 20
424641 AB001106 Hs 151413 glia maturation factor, beta 20 427616 AI698684 Hs 98028 ESTs 20
435115 A1821726 Hs 116603 ESTs 20
437636 AA764781 Hs 291844 ESTs 20
438295 AI394151 Hs 37932 ESTs 20
439430 AF124250 Hs 6564 breast cancer and estrogen resistance 3 20
445388 A1925280 Hs 236842 EST 20
447101 N72185 Hs 44189 ESTs 20
448796 AA147829 Hs 33193 ESTs, Highly similar to AC0072283 BC372 20
449623 C00719 Hs 120440 ESTs 20
450159 AI702416 Hs 200771 ESTs, Weakly similar to CAN2.HUMAN CALPA 20
456613 R19992 Hs 106620 Homo sapiens clone 23950 mRNA sequence 20
457233 AI355009 Hs 221698 ESTs 20
457384 AA501760 Hs 18075 chromosome 9 open reading frame 3 20
457471 AW971364 gb EST383453 MAGE resequences, MAGL Homo 20
TABLE 27B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT number
409457 1132521.1 AW818081 AW392887 AW514700 AW392881
409519 113722 1 AA075368 AA075369
410008 116812 1 AA079552 BE142525 BE142527
410785 1221055 1 AW803341 AW803265 AW803403 AW803466 AW803402 AW803413 AW803268 AW803396 AW803334 AW803355
411050 1230330 1 AW814902 BE156656 BE156667 BE156590 BE156441 BE156447
411880 1263110 1 AW872477 BE088101 T05990
411905 1265181 1 BE265067 BE264978 AW875420
412303 1288130.1 AW936336 AW936339
413136 1350379 1 BE066941 BE066911 BE066979 BE066929 BE066925
413499 1373910 1 BE144884 H97942
413875 1396766 1 BE176776 H85072
415094 1522103 1 D59513 D59515 D80174 D59514
415362 1534980.1 F06735 R55896 R12110 H08697
416624 1604694 1 H69044T47567 H75691 T50292
418378 174656 1 AW962081 AA218925 AA354237
419546 185766 1 AA244199 AA244272 H57440
419807 188252 1 R77402 AA262462 AA250988 R06794
420637 195241 1 AW976153 AA278945 AA747691
422429 216469 1 AA310527 AW962295 Z44865 H06641
423377 22769 1 AL049377 AL079930 AL047223 AW885968 AA385235
426384 26621Ϊ 1 AI472078 AA377209 AA865807
428637 293660 1 AW979268 AA878419 AA431342 AA431628
430153 313709 1 AW968128 AA468102 AA468165
430844 324570 1 T94960 AA487679T95013
431120 328264 1 AA492588 AA492498 AA492571
431169 328799 1 AW971240 AA493843 AA493723
431322 331543 1 AW970622 AA503009 AA502998 AA502989 AA502805 T92188
432009 34025.1 AL137424 BE007148 T52277
432222 343347.1 AI204995 AW827539 AW969908 AW440776 AA528756
432507 348711 1 BE391093 AA551334 BE389643
432779 354024 1 AW979241 AA565006 AA847102
432803 354267.1 AA565398 AW894072 H97930
432869 355475 1 AW974094 AA569074 AA602574
432974 356950 1 BE348793 AA573118 N79366
433492 367934 1 AW605849 AW262898 N41060 AA594852
433584 370400 1 AW295399 AW207772 AW300641 AW070290 BE348854 AW170383 AA600968 AA778832
433687 373061 1 AA743991 AA604852 AW272737
434803 393471 1 AW974640 AA649516 N75626
436148 41500 1 BE005252 AK000786
437327 43610 1 AL353942AW994305
438909 46684 1 AF085839 R69137 AW188788 R69254
440320 491930 1 AA879294 N67538AI474541
444314 600667 1 AI140497 AW749625 AW749626 AW749644
444610 612257 1 AI174783 R83569 R12271
446346 673545 1 AI290205 AW235762 AI651268
447197 711623 1 R36075 AI366546 R36167
448404 761515 1 BE089973 A1498612 A 805032
449299 80436 1 AA299919 AW957012 AA001107 T83631 BE156389
449540 80945 2 AA001713 H63836
449677 81270 1 AA002071 AA002232 T99209
450522 837264 1 AI698839 AI909260 A1909259
451024 85565 T AA442176 AA259181
451381 867770 1 BE241831 AW249135 BE548847 AW250245
452163 902067.1 A1863140 80703 R43474
452293 909195 -1 AI871833
452453 918300 1 AI902519 AI902518 A1902516
452542 921410 1 AW812256 AW812257 AI906423 AI906422
452771 930983 1 T05477 T07855 A1917711
454359 1130674 1 N71277 AW390764 454693 12291321 AW813428 AW813444 AW813367 AW813368 AW813429 AW813424
455024 12491961 AW851309 AW850888 AW851419 AW851412 AW851299
455226 12625341 AW902103 AW869012 AW869139
455235 12656341 AW875951 AW875950 AW875936 AW875948 AW875939 AW875957
455673 13496561 BE065939 BE066079 BE065956
455807 13709141 BE141140 BE141139 BE141105 BE141143 BE141127 BE141202 BE141108
456034 142696.1 AW450979 AA136653 AA136656 AW419381 AA984358 AA492073 BE168945 AA809054 AW238038 BE011212 BE011359 BE011367
BE011368 BE011362 BE011215 BE011365 BE011363
457471 3409161 AW971364AA525021 AA570759
457620 3715141 AA602711 BE078290
458154 4917681 AW816379 AA888282 AA879046 AA879195
459267 9666051 AJ003631 AJ003650 AJ003651
TABLE 27C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489 495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400610 9887671 Minus 117606-117928,124040-124147
400880 9931121 Plus 29235-29336,36363-36580
401049 7232177 Plus 149157-150692
401335 9884881 Plus 15736-16352
401575 7229804 Minus 7625376364
401793 7263888 Minus 102945-103083
401987 4406829 Minus 72893-73021,76938-77049
402046 8072415 Plus 166394-166556,168167-168395
402222 9958106 Plus 3261-3834,39394269
402481 9797406 Plus 87891-88991
402629 9931216 Plus 33641-3377534182-34372,36003-36084,40343-40612
403760 7712202 Minus 45910-46260,47563-47824
403903 7710671 Minus 101165-102597
403937 7711761 Minus 12609-12773
404043 9558573 Plus 29042-29135,46597-46699
404200 6010176 Minus 7066-7210
404274 9885189 Plus 104127-104318
404288 2769644 Plus 3512-3691
404289 2769644 Plus 15049-15286,30267-30457
404323 9719753 Minus 31913-32219
404488 8113286 Minus 64835-64994
404548 8570305 Minus 83896-84162
404593 9944086 Minus 74922-75788
404599 8705107 Plus 110443-110733
404916 7341826 Plus 91057-91188
405041 7547195 Plus 121230-121714
405095 8072599 Plus 138877-139066
405472 8439781 Plus 106297-106447,108462-108596
405494 8050952 Minus 70284-70518
405848 7651808 Minus 28135-28244
405963 8247786 Plus 4056-4699
406182 5923650 Minuε 28256-28935
406485 7711305 Plus 125036-125422
406506 7711374 Minuε 6843-8077
406554 7711566 Plus 106956-107121
406594 8248611 Minus 35543-35845
TABLE 28A ABOUT 796 GENES DOWN-REGULATED IN LUNG FIBROSIS COMPARED TO NORMAL BODY
Table 28A lists of about 796 genes that are downregulated in lung fibrosis (collxtion of IPF, HP, and NSIP) samples as compared with normal "body map" samples These were selxted from about 59680 probesets on an Affymetπx/Eoε Hu03 GeneChip array εuch that the ratio of "average" fibrosis sample expresεion level to "average" normal adult tissues sample expresεion was less than or equal to 0 1 The "average" normal lung tissue level was set to the 75th percentile amongst normal lung tissues The "average" fibrasis expression level was εet to the 95"1 percentile amongεt fibrosis samples In order to remove gene-spxific bxkground levels of non-spxific hybndization, the 15* percentile value amongst non-malignant tisεues was subtracted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number UnigenelD Unigene number Unigene Title Unigene gene title
R1 Ratio of normal lung to fibrosis
Pkey ExAccn Unigene ID Unigene Title R1
414002 NM.006732 Hs 75678 FBJ munne osteosarcoma viral oncogene h 18 18 421218 NM.000499 Hs 72912 cytochrome P450, subfamily I (aromatic c 939 404518 AI815601 Hs 79197 CD83 antigen (xtivated B lymph∞ytes, i 8 30 404795 556 403211 546
417967 BE244373 Hs 1119 nuclear receptor subfamily 4, group A, m 543
400489 5 18
425571 AJ007292 Hs 158306 ephnn A2 5 19
406357 508
407979 AA046306 Hs 62927 ESTs 5 08
452378 AA025855 Hs 19597 ESTs 478
408053 AW139474 Hs 246862 ESTs 462
421770 AA374192 Hs 108124 πbosomal protein L41 452
425126 N32759 Hs 172944 chorionic gonadotropin, beta polypeptide 4 49
402386 439
402448 437
448245 A1923551 Hs 170843 ESTs 431
413778 AA090235 Hs 75535 myosin, light polypeptide 2, regulatory, 429
419968 X04430 Hs 93913 interleukin 6 (interferon, beta 2) 424
447768 X86400 Hs 19520 FXYD domain-containing ion transport reg 421
405163 419
437120 AI356125 Hs 157767 ESTε, Weakly similar to human HOXA2 [H s 4 19
409020 AA062549 Hs 21162 ESTs 409
431073 BE254470 Hs 249186 cone rod homeobox 407
433495 AW373784 Hs 71 alpha-2-gIycoproteιn 1 , zinc 405
403716 399
424969 AW950928 Hs 153998 creat e kmase, mitochondnal 1 (ubiqui 394
404348 390
407070 Y10209 gb H sapiens mRNA for CD30L protein 382
412919 A1368680 Hs 816 SRY (sex determining region Y)-box 2 3 81
402409 380
456150 Z42308 gb HSC0FB121 normalized infant brain cDN 379
427030 AA397600 Hs 97531 ESTs 376
426328 AW631296 gb hh83c09 y1 NCI.CGAP.GU1 Homo sapiens 374
429307 AU076592 Hs 198951 jun B prato oncogene 371
400172 370
431227 X63755 Hs 2743 keratin, cuticle, ultrahigh sulphur 1 368
433883 A1925688 Hs 222312 ESTs, Weakly similar to B24264 proline r 3 68
446850 R71245 Hs 174303 ESTs 367
405147 364
406821 AA977896 Hs 128873 ESTs, Highly similar to ALFA.HUMAN FRUCT 357
402762 355
401496 350
421201 AW241940 Hs 102500 hypothetical protein FU20481 350
402911 349
425330 D25216 Hs 155650 KIAA0014 gene product 349
438004 AA774984 Hs 220649 ESTs, Weakly similar to FCE2 MOUSE LOW A 346
448185 AI633040 Hs 172730 ESTs 346
433367 AA584930 Hs 269451 ESTs, Weakly similar to XAP-5-lιke prote 343
416596 H67669 Hs 38564 ESTs 341
400545 339
418464 R87580 gb ym89h07 r1 Soares adult brain N2b4HB5 337
426507 AA380285 gb EST93491 Supt cells Homo sapiens cDNA 335
403479 334
406082 S47833 Hs 82927 adenosme monophosphate deamiπase 2 (iso 334
401919 333
449031 AI867502 Hs 271462 ESTs 333
400116 3 31
401590 329
401007 328
404610 H58589 Hs 35156 Homo sapiens cDNA FU11027 fis, clone PL 325
408641 AW245207 Hs 5555 Homo sapiens cDNA FU13170 fis, clone NT 325
407196 D11747 Hs 177415 Finkel-Biskis-Reilly munne sarcoma viru 323
410258 X52638 Hs 739 6-phosphofructo-2-kmase/fructose-2,6-bι 323
433232 AI658621 Hs 127769 ESTs 3 23
457937 AW976930 Hs 128760 ESTs 323
406101 3 18
407080 Z38133 Hs 113973 myosin, heavy polypeptide 8, skeletal mu 318
419947 AW298744 Hs 118894 ESTs 316
421905 A1660247 Hs 32699 ESTs, Weakly similar to UV-1 protein [H 3 16
454019 D31846 Hs 37025 aquapoπn 2 (collxfiπg duct) 316
428674 AA431734 Hs 104915 ESTs 3 14
402056 306
425182 AF041259 Hs 155040 zinc finger protein 217 3 06
425393 NMJ00218 Hs 156115 potassium voltage-gated channel, KQT-lik 306
433657 AI244368 Hs 8124 PH domain containing protein in retina 1 305
402158 303
404938 302
403376 301
418828 AF020774 Hs 88844 Homo sapiens hair and skin epidermal typ 300
402423 299
416253 BE250659 Hs 15463 ESTs 299
435265 AA779958 Hs 185932 ESTs 299
425655 BE614551 Hs 158675 πbosomal protein L14 298
428704 AA432007 Hs 249484 ESTε 298
425439 D38024 Hs 157425 double homeobox, 2 297
445613 BE550889 Hs 158491 ESTs 297 402714 296
403526 296
403605 295
441852 AB028968 Hs 7989 KIAA1045 protein 2 95
417629 T76945 Hs 64211 ESTs, Weakly similar to εimilar to acyl 294
447744 AA313230 Hs 19413 S100 calcium binding protein A12 (calgra 291
419821 AW967486 Hs 189119 ESTε 290
446993 A1570964 Hs 164257 ESTs 289
414580 BE386918 gb 601275386F1 NIH_MGC_20 Homo εapieπε c 288
423379 AI985349 Hs 157492 Homo sapiens cDNA FLJ 14079 fis, clone HE 288
440206 AI762232 Hs 46794 ESTs 2 88
402212 AW502761 Hs 30909 KIAA0430 gene product 287
406059 286
423548 AF007194 Hs 129782 mucin 3A, intestinal 286
402051 285
415196 AK000150 Hs 78185 MAX like bHLHZIP protein 2 85
455446 AW947749 gb RC0 MT0005 130300-031-b01 MT0005 Homo 285
442428 BE464988 Hs 298302 ESTs 284
403247 283
404825 283
459184 L35001 Hs 95669 ESTs 2 83
402968 282
417575 R00382 Hs 191199 ESTs 282
404668 281
420619 AF130255 Hs 99430 testis zinc finger protein 281
447241 BE382838 Hs 19322 ESTs 280
448793 AI864581 Hs 215477 ESTs 279
453014 AI837242 Hs 176590 ESTs 279
446775 AI792836 Hs 232273 ESTs 278
455075 AW854850 gb QV2-CT0261-201099 011-h03 CT0261 Homo 278
406704 M21665 Hs 929 myosm, heavy polypeptide 7, cardiac mus 275
457546 AA568484 Hs 153632 ESTs 275
410197 NM 005518 Hs 59889 3-hydroxy-3-methylglutaryl Coenzyme A sy 2 4
433677 AI791912 Hs 190885 ESTs, Moderately similar to ALULHUMAN A 274
405703 273
408840 AW277132 Hs 254880 ESTs 273
413958 BE277913 Hs 172364 Homo sapiens mRNA for FLJ00086 protein, 273
454421 BE409759 Hs 59563 Homo sapiens mRNA for FLJ00007 protein, 273
406702 Z20656 Hs 278432 myosin, heavy polypeptide 6, cardiac mus 272
408664 R56362 gb yg93c07 r1 Soares infant brain 1 IB H 272
402457 271
403612 271
407049 X72632 (NONE) 271
415423 AA164743 Hs 187617 Homo sapiens cDNA FLJ13941 fis, clone Y7 270
402862 269
403540 269
431465 AW293178 Hs 180086 ESTs 269
406563 268
417003 AL038170 Hs 80756 betame homxysteme methyltransferase 268
426220 AI383475 Hs 171697 ESTs, Weakly similar to immunoglobulin s 268
446707 AI591214 Hs 156336 ESTs 268
447557 AW028809 Hs 229570 ESTs 268
413529 U11874 Hs 846 interieukm 8 rxeptor, beta 267
403997 266
408704 AA056635 Hs 5366 Homo sapiens cDNA FU21522 fis, clone C 266
407005 U20230 gb Human guanyl cyclase C gene, partial 265
405075 264
430728 AW968522 gb EST380598 MAGE resequenceε, MAGJ Homo 264
405327 263
409419 BE207219 Hs 20474 ESTε, Highly similar to S17112 mterfero 263
434300 AA740944 Hs 116295 ESTs 263
405895 262
431929 AW294163 Hs 146127 ESTs 261
405217 260
437569 AA760849 Hs 294052 ESTs 260
419822 AW966864 Hs 255780 ESTs 259
445918 AW014139 Hs 145656 ESTs 259
446149 BE242960 Hε 203181 ESTs 259
457829 AI742291 Hε 210843 ESTs, Weakly similar to dJ1039K5 2 [H sa 258
404282 253
409778 AW499705 gb UI-HF-BROp-ajk-b-05 0-UM NIH MGC 5 253
445353 BE551465 Hε 175211 ESTs 253
458764 BE619386 gb 601473204F1 NIH_MGC_68 Homo sapienε c 253
402195 252
404247 252
427584 BE410293 Hs 179718 v-myb avian myeloblastosis viral oncogen 2 52
402588 250
432301 U34249 Hs 167075 nng finger protein 9 250
424958 AA984420 Hs 283659 ESTs 249
442197 AW837912 gb QV3 LT0048 260100-068-C02 LT0048 Homo 249
415003 M11437 Hs 77741 kininogeπ 248
420767 AF072711 Hs 99918 carboxyl ester lipase (bile salt stimula 248
422885 BE244068 Hs 121544 interleukin 12 rxeptor beta 1 247 440424 AI991125 Hs 189109 Homo sapiens cDNA FLJ21458 fis, clone C 247 246
432152 AK000245 Hs 272790 Homo sapiens cDNA FLJ20238 fis, clone CO 246
454414 R55574 Hs 164675 ESTs 245
401603 244
408483 BE206854 Hs 46039 phosphoglycerate mutase 2 (muscle) 244
408513 AW206468 Hs 103118 ESTs 243
409826 AW501112 Hs 34487 hypothetical protein FLJ23412 242
400672 241
430713 AA351647 Hs 2642 eukaryotic translation elongation factor 241
449748 H23963 Hs 32043 ESTs 241
453756 AW139415 Hs 61906 ESTs 241
400624 240
403125 240
406118 239
402165 238
416982 J05401 Hs 80691 creatme kinase, mitochondnal 2 (sarcom 2 38
425515 W26609 gb 35f12 Human retina cDNA randomly prim 238
402951 237
427886 AA417083 Hs 104789 ESTs 237
447173 AW449385 Hs 157294 ESTs 237
448703 BE613942 Hs 170890 Homo sapiens cDNA FU21129 fis, clone C 237
426344 H41821 Hs 169393 transcriptional activator of the c-fos p 236
401840 235
403731 234
405378 234
405555 Y09306 Hs 30148 homeodomam interacting protein kinase 3 234
416559 AI039195 Hs 128060 ESTs, Weakly similarto cDNA EST yk481g5 234
438216 Z83952 Hs 252815 ESTs 234
448427 BE395260 gb 601311130F1 NIH.MGC.44 Homo sapiens c 234
451588 AW072057 gb ws58g05 x1 NCI CGAP_Brn25 Homo εapien 234
423011 NM 000683 Hs 299847 ESTs, Highly similar to A2AD HUMAN ALPHA 2 33
451172 AW206465 Hs 207423 ESTε 233
401015 2 32
414705 BE464157 Hs 281455 ESTε 232
439894 AA853077 gb NHTBCae03a05f1 Normal Human Trabecula 231
446305 AW270149 Hs 254515 ESTε, Moderately similar to AF248953 1 g 231
453512 AL040160 Hs 209542 ESTs, Weakly similar to B cell linker pr 229
418556 T02850 gb FB12A9 Fetal brain, Stratagene Homo s 228
457197 AB016092 Hs 197114 RNA binding protein, AT-πch element bin 228
457275 AA463422 Hs 209431 ESTs 228
458766 AW183618 Hs 188417 ESTs, Weakly similar to ZnT-3 [H sapiens 228
414075 U11862 Hs 75741 amiloπde binding protein 1 (amine oxida 227
430210 AL157426 Hε 235390 Homo sapiens mRNA, cDNA DKFZp761B101 (fr 227
442614 AI269030 gb qj73c12 x1 NCI_CGAP_Kιd3 Homo εapiens 2 27
402538 226
439891 AL389940 Hs 109968 ESTs 226
440056 BE294828 Hs 13323 hypothetical protein FU22059 226
406150 225
426880 AA453482 gb zx47a11 r1 Soares teεtis NHT Homo εap 225
447129 AW014123 Hs 161402 ESTs 225
458893 BE161733 Hs 97283 ESTs, Weakly similar to ALULHUMAN ALU S 225
456778 AI458309 Hs 117406 ESTs 224
401728 223
404139 223
414095 BE293546 gb 601186671F1 NIH.MGC 15 Homo sapiens c 223
432037 AW450592 Hs 300459 ESTs 223
451965 AA021163 Hs 22287 ESTs 223
416768 AA363733 Hs 1032 regenerating islet deπved 1 alpha (pane 222
427586 AA609661 Hε 190592 ESTs 222
454108 AA161071 Hs 71465 squalene epoxidase 222
429749 AI685174 Hs 22293 ESTs 221
434507 AW511138 Hs 256581 ESTs 221
436652 AA724543 Hs 168824 ESTε 221
437433 R74016 Hs 121581 ESTs 221
401688 220
441748 R14439 Hs 209194 ESTs 219
453072 BE251845 Hs 221516 ESTs, Weakly similar to tetraspan TM4SF 219
400635 2 18
417176 AW974475 Hs 143467 ESTs 218
427858 NM.001971 Hs 21 elastase 1, pancreatic 218
454886 AW837063 gb QV1-LT0037-150200-069-g08 LT0037 Homo 218
458232 BE217872 Hs 279537 ESTs 218
408922 R87388 gb ym88g04 r1 Soares adult brain N2b4HB5 217
423668 Y10148 Hs 131138 neuroteπsin receptor 2 217
440338 R62431 Hs 12758 ESTε 217
403115 2 16
409125 R17268 Hs 301560 ESTs 216
426887 AI971975 Hs 212892 ESTs 2 16
413811 BE168828 gb QV1-HT0517-020400 145 f04 HT0517 Homo 215
442962 AI025315 Hs 131615 ESTs 215
403921 214
413140 T06607 Hs 6846 hypothetical protein FLJ 13055 214 421996 AW583807 Hs 1460 glucagon 2 14
436130 AA341497 Hs 31408 ESTs 214
407243 AA058357 Hs 74466 carcmoembryonie antigen-related cell ad 2 13
407708 AF019968 Hs 37936 suppreεsor of variegation 3-9 (Drosophil 213
442792 AI352340 Hs 131194 ESTs 2 12
454406 AA213605 Hs 267861 ESTs 2 12
424648 AA344576 gb EST50478 Gall bladder 1 Homo sapiens 211
433963 AI218808 Hs 187778 ESTs 2 11
400736 210
406343 2 10
409702 AI752244 Hs 285749 Human DNA from chromosome 19 specific co 210
432092 AF135026 gb Homo sapiens kallikrein like protein 210
441915 AI566116 Hs 207066 ESTs, Weakly similar to FOG [M musculus] 210
453147 AA733098 Hs 279909 CGI 05 protein 210
415604 Z44177 Hs 170434 Homo sapiens cDNA FLJ14242 fis, clone OV 208
422927 AW247388 Hs 301423 calcium binding protein 1 (calbrain) 208
401211 AJ004832 Hs 5038 neuropathy target esterase 207
413808 J00287 Hs 182183 caldesmon 1 207
414433 BE407755 Hs 169100 Homo sapiens cDNA FLJ 12529 fis, clone NT 207
421978 AJ243662 Hs 110196 NICE-1 protein 207
431204 F28841 Hs 250760 cytxhrome c oxidase subunit Via polypep 207
433605 AI378012 Hs 147953 ESTs 206
449383 AW444712 Hs 196573 ESTs 206
455652 BE064675 gb RC1-BT0313-301299 012 hi 1 BT0313 Homo 205
402382 204
407282 AI345597 Hs 254727 ESTs 204
457273 AI167145 Hs 165538 ESTs 204
459073 AW968616 Hs 296234 ESTs, Highly similar to mitogen-acfivate 204
402394 203
428875 AW451624 Hs 178202 ESTs 203
456634 AA609911 Hs 109012 ESTs 203
434352 AF129505 Hs 86492 small muscle protein, X-lmked 202
439281 AA100768 Hs 48485 ESTs 202
444153 AK001610 Hs 10414 hypothetical protein FLJ 10748 202
401122 201
444340 AI143198 Hs 143561 ESTs 201
455104 BE064863 gb RC1-BT0313 110300 015406 BT0313 Homo 201
415011 AW963085 gb EST375158 MAGE resequenceε, MAGH Homo 200
440144 AW082297 Hs 88523 ESTε 200
403183 1 99
409802 AW500732 gb UI-HF-BN0 akm h-07-0-Ul r1 NIH MGC 50 1 98
430144 AI732722 Hs 187694 ESTε 1 98
444580 AI168365 Hs 268663 ESTs 1 98
401704 1 97
401810 1 97
424473 AK001405 Hs 148584 Homo sapiens cDNA FLJ 10543 fis, clone NT 1 97
438573 AW135084 Hs 299865 ESTs 1 97
412921 BE009345 Hs 128942 ESTs 1 96
422233 AB002058 Hs 113275 puπnergic rxeptor P2X-lιke 1, orphan r 1 96
425352 NM.000939 Hs 1897 proopiomelanxortin (adrenxorticotropin 1 96
410285 AA083609 gb zm63d05 r1 Stratagene fibroblast (937 1 95
414323 NM_014759 Hs 239500 KIAA0273 gene product 1 94
428119 AW298211 Hs 255737 ESTs 1 94
424510 AK001841 Hs 149797 hypothetical protein FLJ 10979 1 92
425280 U31519 Hs 1872 phosphoenolpyruvate carboxykmase 1 (sol 1 92
429785 H82114 Hs 301769 ESTs 1 92
437344 R90921 Hs 6846 hypothetical protein FU13055 1 92
451819 AI819096 Hs 249260 ESTs 1 92
459060 H88244 Hs 79625 heterogeneous nuclear nbonucleoprotein 192
422664 AA315933 Hs 120879 ESTs 1 91
432247 AA531287 Hs 105805 ESTs 1 91
453820 R77494 Hs 75416 DAZ asεxiated protein 2 1 91
400675 1 90
405556 Y09306 Hs 30148 hom∞domain interacting protein kinase 3 1 90
407099 M94891 Hs 278423 pregnancy spxific beta-1-glycoproleιn 4 1 90
440297 BE560553 Hs 205450 Homo sapiens cDNA FLJ22570 fis, clone H 1 90
443104 AA088470 Hs 83135 p53-responsιve gene 6 1 90
444329 W73753 Hε 58330 ESTs 1 90
402690 1 89
432354 AW137262 Hε 192713 ESTs 1 89
427811 M81057 Hε 180884 carboxypeptidase B1 (tisεue) 1 88
443322 AI825817 Hs 143272 ESTε 1 88
458185 AI762757 Hs 129869 ESTs, Weakly similar to AF113685 1 PRO09 1 88
459072 AI815978 Hs 160427 ESTs 1 88
402534 1 87
409689 AA078492 gb 7P04D11 Chromoεome 7 Placental cDNA L 1 87
416931 D45371 Hs 80485 adipose most abundant gene traπscπpt 1 1 87
430176 AL161995 Hs 234775 neurtuπn 1 87
430631 AJ003147 Hs 278464 olfactory rxeptor, family 1, subfamily 1 87
433114 AA121579 gb zn77f02 r1 Stratagene NT2 neuronal pr 1 87
439254 U57352 Hs 6517 amiloπde-sensitive cation channel 1, ne 1 87
448461 AW166358 Hs 124979 ESTs 1 87
450675 AA010662 Hs 188639 ESTs 1 87 401767 186
449891 N64867 Hs 37848 ESTs 185
400527 184
428581 AA430570 Hs 104881 ESTs 184
443647 AV653846 Hs 126261 Homo sapiens Chromosome 16 BAC clone CIT 184
444785 AV651441 Hs 282475 ESTs 184
449566 AA001778 Hs 288156 Homo sapiens cDNA FLJ21819fis clone H 184
436752 AW298529 Hs 255774 ESTs 183
437405 AA338837 Hs 42547 Homo sapiens cDNA FLJ13975 fis clone Y7 183
449174 T66136 Hs 12880 ESTs 183
449887 AW080843 Hs 200275 ESTs 183
453261 AA034116 Hs 118494 ESTs 183
454243 AW241901 Hs 250683 ESTs 183
459188 AA216382 Hs 30002 SH3-contaιnιng protein SH3GLB2 183
424334 AA393460 gb zt71e05 r1 Soareε_testιs_NHT Homo εap 182
432150 AK000224 Hs 272789 hypothetical protein FU20217 182
408123 AW163377 gb au94e02 y1 Schneider fetal brain 0000 181
428722 U76456 Hs 190787 tisεue inhibitor of metalloproteinase 4 180
442196 AI902646 Hs 31844 Homo sapiens cDNA FLJ12586 fis clone NT 180
421419 M99587 Hs 104134 homx box (H6 family) 1 179
405420 178
405737 178
414016 AA134594 Hs 71528 ESTs 178
415744 AW964850 Hs 279307 ESTs 178
420375 AF182077 Hs 97244 glio a tumor suppresεor candidate region 178
426322 J05068 Hs 2012 transcobalamin 1 (vitamin B12 binding pr 178
421592 AF009801 Hs 105941 bagpipe homeobox (Drosophila) homolog 1 177
401743 175
405187 175
442763 AI017037 Hs 131121 ESTs 175
451621 AI879148 Hs 26770 fatty acid binding protein 7 brain 175
413248 T64858 Hs 21433 ESTs 174
423913 NM 016436 Hs 301055 hepatocellular carcinoma-ass∞iated anti 174
439999 AA115811 Hs 6838 ras homolog gene family member E 174
440185 AW104546 Hs 270929 ESTs 174
450482 AI697844 Hs 221720 ESTs 174
413972 BE279548 Hs 162717 ESTs Weakly similar to HPPD.HUMAN 4-HYD 173
420476 AW575863 Hs 136232 ESTs 173
428748 AW593206 Hs 98785 ESTs 173
431148 AA502653 Hs 28621 ESTs 173
447205 BE617015 Hs 11006 ESTs 173
455994 BE179190 gb RC0 HT0613-210300032 f07 HT0613 Homo 173
401039 172
403251 172
409762 AW498884 Hs 257970 ESTs 172
440914 AA909552 Hs 143884 ESTs 172
448507 AL133109 Hs 21333 Homo sapiens mRNA cDNA DKFZp566N1047 (f 172
409605 AW444477 Hs 258507 ESTs 171
441212 AW242447 Hs 146182 ESTs Weakly similar to lactase phloπzi 171
445624 AW140103 Hs 78880 ilvB (bxteπal xetolxtate synthase) I 171
458619 AA872064 Hs 301218 ESTs Weakly similar to Unknown gene pro 171
401969 170
403327 170
407245 X90568 Hs 172004 titin 170
417361 NM 000275 Hs 82027 ∞ulxutaneous albinism II (pink-eye dil 170
436034 AF282693 Hs 150185 inflammation related G protein-coupled r 170
442682 AI014545 Hs 231027 EST 170
458494 AI380906 Hs 158436 ESTs 170
404682 169
407402 AF035303 gb Homo sapienε clone 23943 mRNA εequenc 169
409368 AA071059 gb zm66a10 r1 Stratagene neuroepithelium 169
440362 AA883812 Hs 125508 ESTs 169
448866 BE297743 Hs 284203 myogenic fxtor 3 169
402201 168
426230 AA367019 Hs 241395 protease senne 1 (trypsin 1) 168
403186 167
408543 AW410200 gb Ih05b12 x1 NIH_MGC_17 Homo sapiens cD 167
443672 AA323362 Hs 9667 butyrabetaine (gamma) 2-oxoglutarate di 167
450391 AI694522 Hs 202280 ESTs 167
408919 AW295352 Hs 251836 ESTs 166
416136 H45027 Hs 181770 ESTs 166
416865 H97863 Hs 42456 ESTs 166
419682 H13139 Hs 92282 paired like homeodomam transcription fa 166
437237 BE513073 gb601171435F1 NIH.MGC 15 Homo sapiens c 166
429134 AA446953 Hs 99004 ESTs 165
445041 T64183 Hs 11398 ESTs 165
453240 AI969564 Hs 284249 Homo sapiens cDNA FLJ22334 fis clone H 165
405243 164
426039 BE265133 Hs 217493 annexm A2 164
430135 NM 000035 Hs 234234 aldolase B fructose bisphosphate 164
435942 R06285 Hs 191215 ESTs 164
448106 AI800470 Hs 171941 ESTs 164
408591 AF015224 Hs 46452 mammaglobm 1 163 410881 AW809157 gb RCO ST0118 041099 031 c07_1 ST0118 Ho 1 63
417743 R14738 Hs 8312 ESTs, Weakly similar to AF170723 1 prote 1 62
430632 AC004597 Hs 248088 olfactory receptor, family 10, subfamily 1 62
448651 BE246440 Hs 93728 pre B cell leukemia transcription factor 1 62
453718 AL119317 Hs 120360 phospholipase A2, group VI (cytosolic, c 1 62
459499 AW402653 Hs 28355 Homo sapiens cDNA FU22402 fis, clone H 1 62
412374 X01388 Hs 73849 apolipopratem C-lll 1 61
419113 AI446586 Hs 21835 ESTs 1 61
426795 AI810474 Hs 196945 ESTs 1 61
426998 BE274360 gb 601121068F1 NIH_MGC_20 Homo sapiens c 1 61
428407 NM 003963 Hs 184194 transmembrane 4 superfamily member 5 1 61
444475 C75571 gb C75571 Human pancreatic islet Homo sa 1 61
453399 Z70295 Hs 32966 guanylate cyclase activator 2B (uroguany 1 61
456275 AW976183 Hs 88414 ESTs, Weakly similar to dJ512E2 1 [H sap 1 61
414060 BE246327 gb TCBAP1E1967 Pediatnc pre-B cell xut 1 60
418004 U37519 Hε 87539 aldehyde dehydrogenase 8 1 60
428651 AF196478 Hs 188401 annexm A10 1 60
443853 AI089064 Hs 250644 ESTs 1 60
407007 U22961 gb Human mRNA clone with similanty to L 1 59
412067 N45697 gb yy78d01 r1 Soares_multιple_sclerosιs_ 1 59
419080 AW150835 Hs 18878 hypothetical protein FLJ21620 1 59
448619 AI867182 Hs 202255 ESTs 1 59
403665 1 58
407524 X64985 gb H sapiens mRNA HTPCRX11 for olfactory 1 58
424286 AA338285 Hs 90744 proteasome (prosome macropain) 26S subu 1 58
412056 T28160 Hs 778 guanylate cyclase activator 1B (retina) 1 57
430218 AW998865 Hs 186703 ESTs 1 57
431882 NM 001426 Hs 271977 engrailed homolog 1 1 57
450797 AI761930 Hs 205127 ESTs 1 57
455366 AW947563 gb RCO MT0004-140300031-g11 MT0004 Homo 1 57
408421 AW193734 Hs 253067 ESTs 1 56
421907 BE018556 Hs 109358 ATPase, Class V, type 10B 1 56
432742 AA564453 Hs 162339 ESTs 1 56
436624 T64297 Hs 5241 fatty acid binding protein 1, liver 1 56
439543 W75935 Hs 1 6083 ESTs 1 56
443317 A1051601 Hs 200191 ESTs 1 56
449097 BE271708 Hs 95110 ESTs, Weakly similar to PIP6.HUMAN 1-PHO 1 56
457127 AA194554 Hs 183434 ATPase, H+ transporting, lysosomal (vxu 1 56
407387 AB000895 gb Homo εapiens mRNA for cadhenn FIB1 , 1 55
418837 U48263 Hs 89040 prepronociceptin 1 55
436749 AA584890 Hs 5302 iectin, galactoside binding soluble, 4 1 55
458475 AI650322 Hs 143249 ESTs 1 55
402561 1 54
411187 AW821291 gb PM3-ST0307-241299 002-f03 ST0307 Homo 1 54
419224 NM.012189 Hs 252716 fibrousheathin II 1 54
414657 AA424074 Hs 76780 protein phosphatase 1, regulatory (inhib 1 53
415426 Z41991 Hs 23197 ESTs 1 53
421428 U26726 Hs 1376 hydroxysteroid (11-beta) dehydrogenase 2 1 53
426300 U15979 Hs 169228 delta like homolog (Drosophila) 1 53
428489 AI807459 Hs 98582 ESTs 1 53
437728 AA766719 gb oa39c09 s1 NCI CGAP GCB1 Homo sapiens 1 53
407124 R08160 Hs 268857 ESTs, Weakly similar to ALULHUMAN ALU S 1 52
414932 C14577 Hs 194517 ESTs 1 52
433500 AF064255 Hs 111401 very long-chain ∞yl CoA synthetase homo 1 52
439688 AW445181 Hs 209637 Homo sapiens cDNA FU12921 fis, clone NT 1 52
453391 AW600302 Hs 232655 ESTs 1 52
424688 AA216287 Hs 1815 myosin, light polypeptide 3, alkali, ven 1 51
436895 AF037335 Hs 5338 carbonic anhydrase XII 1 51
443012 AI566813 Hs 132278 ESTs 1 51
415824 D42039 Hs 78871 mesoderm development candidate 2 1 50
445152 AI214667 Hs 283597 ESTs 1 50
455941 BE160011 Hs 129998 Homo sapiens cDNA FU14267 fis, clone PL 1 50
457889 AL035864 Hs 69517 ESTs, Highly similar to differentially e 1 50
458503 AL133933 Hs 64310 interleukin 11 receptor, alpha 1 50
400694 1 49
420937 AW966719 Hs 1340 colipase, pancreatic 1 49
426752 X69490 Hs 172004 trim 1 49
426784 U03749 Hs 172216 chromogranin A (parathyroid sxretory pr 1 49
428874 W32133 Hs 194366 transthyretin (prealbumiπ, amyloidosis t 1 49
444287 AI033077 Hs 10755 dihydropyπmidinase 1 49
450684 AA872605 Hs 25333 interieukin 1 rxeptor, type II 1 49
425747 AI457620 Hs 205360 ESTε 1 48
432378 AI493046 Hs 146133 ESTs 1 48
447999 AW138840 Hs 201778 ESTs 1 48
453888 AW450670 Hs 252819 ESTs 1 48
406667 M12523 Hs 75442 albumin 1 47
418129 X52997 Hs 1144 glycoprotein IX (platelet) 1 47
426309 AI912555 Hs 157195 peptide YY, 2 (semmalplaεmin) 1 47
426755 BE253469 gb 601108143F1 NIH.MGC.16 Homo sapiens c 1 47
414258 AA203285 Hs 294141 ESTs, Weakly similarto dJ733D15 1 [H sa 1 46
417421 AL138201 Hs 82120 nuclear rxeptor subfamily 4, group A, m 1 46
420562 AI345569 Hs 190046 ESTs 1 46
425011 T51986 Hs 283108 hemoglobin, gamma G 1 46 443050 AI612788 Hs 132348 ESTs, Weakly similar to diaphanous 1 [H 1 46
411074 X60435 Hs 68137 adenylate cyclase activating polypeptide 1 45
434680 T11738 Hs 127574 ESTs 1 45
454771 AW819939 Hs 273629 ESTs 1 45
415672 N53097 Hs 193579 ESTs 1 44
418141 AW845738 Hs 171118 Homo sapienε mRNA for FLJ00026 protein, 1 44
406706 X03740 Hs 231581 myosin, heavy polypeptide 1, skeletal mu 1 43
418197 AA214253 gb zn58g02 r1 Stratagene muscle 937209 H 1 43
431821 AW452256 Hs 271221 hypothetical protein FU20064 1 43
455433 AW939463 gb QV1 DT0072-310100 056-g02 DT0072 Homo 1 43
407743 AW814118 gb MR3-ST0203-151199011-d09 ST0203 Homo 1 42
418888 AU076801 Hs 89436 cadhenn 17, LI cadhenn (liver-intestiπ 1 42
434001 AW950905 Hs 3697 seπne (or cysteine) proteinase inhibito 1 42
441031 AI110684 Hs 7645 fibrinogen, B beta polypeptide 1 42
452456 BE080763 gb QV1-BT0631-150200 071409 BT0631 Homo 1 42
456535 AA305079 Hs 1342 cytochrome c oxidase subunit Vb 1 42
408349 BE546947 Hs 44276 homeo box C10 1 41
420391 AA456891 Hs 79123 KIAA0084 protein 1 41
421126 M74587 Hs 102122 insulin like growth factor binding prote 1 41
449329 AW752783 gb IL3-CT0219-221199 029-F03 CT0219 Homo 1 41
453615 AA195712 Hs 132696 ESTs 1 41
417296 L36196 Hs 81884 sulfotransferase family, cytosolic, 2A, 1 40
420287 AA740907 Hs 88297 ESTs 1 40
427583 M82962 Hs 179704 mepπn A, alpha (PABA peptide hydrolase) 1 40
418787 AW296134 Hs 86999 ESTs 1 39
422072 AB018255 Hs 111138 KIAA0712 gene product 1 39
425988 BE045897 Hs 274454 ESTs 1 39
428087 AA100573 Hs 182421 troponiπ C2, fast 1 39
438136 NM 002390 Hs 6088 a disintegnn and metalloprotemase doma 1 39
455579 BE011320 gb PM3 BN0218 090500 002-d09 BN0218 Homo 1 39
402316 1 38
417084 H08370 Hs 33067 ESTs 1 38
423276 AC003034 Hs 126261 Homo sapiens Chromosome 16 BAC clone CIT 1 38
433787 AI472951 Hs 173688 ESTs 1 38
413830 BE263439 Hs 13144 HSPC160 protein 1 37
423576 NM_000383 Hs 129829 autoimmune regulator (automimmuπe polyen 1 37
401886 1 36
412688 AW583062 Hs 74502 chymotrypsmogen B1 1 36
401238 1 34
421511 AA488940 Hs 105216 hypothetical protein FU11125 1 34
422440 NM.004812 Hs 116724 aldo-keto redu ase family 1, member B11 1 34
425450 U14755 Hs 157449 UM hom∞box protein 1 1 34
427333 AF067797 Hs 176658 aquapoπn 8 1 34
430937 X53463 Hs 2704 glutathione peroxidase 2 (gastrointestin 1 34
445204 AW135523 Hs 245853 ESTs 1 34
452030 AL137578 Hs 27607 Homo sapiens mRNA, cDNA DKFZp564N2464 (f 1 34
456379 W22206 gb 63E10 Human retina cDNA Tsp509l-cleav 1 34
457416 BE142052 gb C 3-HT0137-150999-011 -b05 HT0137 Homo 1 34
415741 AI902761 Hs 272087 ESTε 1 33
422260 AA315993 Hs 105484 ESTs, Weakly similar to LITB.HUMAN LITHO 1 33
429188 AB011171 Hs 198037 KIAA0599 protein 1 33
442776 AW959498 Hs 8709 chymotrypsin C (caldxnn) 1 33
454748 AW862014 gb RC3-CT0347-160200 013-d09 CT0347 Homo 1 33
437744 AW290905 Hs 300288 ESTs, Weakly similar to CGHU2E collagen 1 32
451997 AA021351 Hs 158497 KIAA0724 gene product 1 32
452340 NM.002202 Hs 505 ISL1 transcnption fxtor, LIM/hom∞doma 1 32
411879 BE145354 Hs 273758 Homo sapiens cDNA FU23112 fis, clone L 1 31
424304 NM.001395 Hs 144879 dual specificity phosphatase 9 1 31
401442 1 30
403842 1 30
443687 F13040 Hs 182937 peptidylprolyl iso erase A (cyclophilm 1 30
401624 1 29
411885 AA452636 Hs 131057 ESTε, Moderately similar to CRGD HUMAN G 1 29
418575 AA225313 Hs 222886 ESTs 1 29
419818 AI657122 Hs 301931 ESTs 1 29
429845 AB020337 Hs 225943 UDP-Gal betaGlcNAc beta 1,3-galxtosyltr 1 29
447586 AI081980 Hs 285828 εolute earner family 25 (mitxhoπdπal 1 29
407013 U35637 gb Human nebulm mRNA, partial cdε 1 28
428470 AC002301 Hs 184507 Homo sapiens Chromoεome 16 BAC clone CIT 1 28
429780 AL137518 Hs 300388 ESTs 1 28
453539 AW731886 Hs 95196 ESTs, Weakly similar to T20B123 [C eleg 1 28
400846 1 27
420257 AA257035 Hs 190042 ESTs 1 27
429184 AF095735 Hs 198003 sarcosine dehydrogenase 1 27
437389 AL359587 Hs 271586 hypothetical protein DKFZp762M115 1 27
444412 AI147652 Hs 216381 Homo sapiens clone HH409 unknown mRNA 1 27
451139 AW293316 Hs 205558 ESTs 1 27
431284 AA570148 Hs 126783 Homo sapiens cDNA FU22610 fis, clone H 1 26
431969 AA366217 Hs 2879 carboxypeptidase A1 (pancreatic) 1 26
406158 1 25
419648 T73661 Hs 91877 ESTs Highly similar to THIH HUMAN THYRO 1 25
430681 AW969675 Hs 291232 ESTs 1 25
434880 U02388 Hs 101 cytxhrome P450, subfamily IVF polypept 1 25 436217 T53925 Hs107 fibrinogen like 1 125
440089 AA864468 Hs 135646 ESTs 125
446787 U67167 Hs315 mucin 2, mtestinal/tracheal 125
448207 AI475490 Hs 170577 ESTs 125
454869 AW836004 gbPMO LT0019-170200-001 d11 LT0019Homo 125
413271 AA127873 Hs 114949 ESTs 124
422619 AA313322 gb EST185218 Colon carcinoma (HCC) cell 124
422796 AW897265 gb CM0-NN0057-150400-335-a04 NN0057 Homo 124
427530 AA405093 Hs 126519 ESTs 124
437727 AA766707 Hs 153039 ESTs 124
426435 AI827946 Hs 189118 ESTs 123
426429 X73114 Hs 169849 myosm binding protein C, slow type 122
407964 AW130334 Hs 281111 ESTs 121
430828 AI763257 Hs 86327 Homo sapienε cDNA FLJ22431 fis, clone H 121
432029 D31628 Hs 2899 4-hydraxyphenylpyruvate dioxygenase 121
457843 AW138211 Hs 128746 ESTs 121
413242 BE074165 gb PM3-BT0564-030300002 e12 BT0564 Homo 120
446057 AI420227 Hs 149358 ESTε 120
447198 D61523 Hs 283435 ESTε 120
449513 AI653232 Hs 195059 EST 120
415566 F12119 gb HSC35H091 normalized infant brain cDN 119
423315 R54109 Hs 26096 ESTs 119
455817 BE142384 gb CM2-HT0144-21099901 U04 HT0144 Homo 119
459354 BE514778 gb 601317094F1 NIH_MGC_9 Homo sapienε cD 119
408432 AW195262 gbxn67b05x1 NCLCGAP.CML1 Homo εapienε 118
414275 AW970254 Hs889 Charot Leyden crystal protein 118
419251 NM 001486 Hs 89771 glucokmase (hexokmase 4) regulatory pr 118
456702 AI684534 gb wa72f10 x1 Soares_NFL.T_GBC_S1 Homo s 118
458009 AI221409 Hs 144983 ESTs 118
410193 AJ132592 Hs 59757 zinc finger protein 281 117
417779 AA829526 Hs 124977 ESTs 117
435101 AI743156 Hs 131064 ESTs 117
445360 AI798776 Hs 156029 ESTs 117
414160 BE257021 gb 601117426F1 NIH_MGC_16 Homo sapiens c 115
418078 AA521268 Hs 86508 ESTs 115
425133 NM.002613 Hs 154729 3-phosphoιnosιtιde dependent protein kin 115
437935 AW939591 Hs 5940 hypothetical protein FLJ20063 115
446377 AW014022 Hs 170953 ESTs 115
420097 AA700127 Hs 190504 ESTs 113
446591 H44186 Hs 15456 PDZ domain containing 1 113
451477 AI798425 Hs 42710 ESTs 113
459197 BE244587 gb TCBAP2E0851 Pedialnc pre-B cell xut 113
428934 AF039401 Hs 194659 chloπde channel, calcium xtivated, fam 112
431191 AW972118 Hs 100002 HSPC162 protein 112
424403 F05183 Hs 1799 CD1D antigen, d polypeptide 111
433546 AI075877 Hs 125461 Homo sapiens cDNA FLJ 11539 fis, clone HE 111
451179 W05469 Hs 31818 ESTε 111
400302 N48056 Hs 1915 folate hydrolase (prostate spxific memb 110
420774 AA280209 Hs 165270 ESTε 110
428887 AA437009 Hs 98984 ESTε 110
430582 AI215509 Hs 143964 ESTs 110
453642 AI370936 Hs 34074 dipepfidylpeptidase VI 110
406690 M29540 Hs 220529 carcinoembryonic antigen related cell ad 109
417998 AW967420 gb EST379495 MAGE reεequenceε, MAGJ Homo 109
456387 W28876 gb 52h7 Human retina cDNA randomly pπme 109
427965 D00306 Hs 183864 elastase 3B 108
447388 AW630534 Hs 76277 ESTs, Weakly similar to TB2 [H sapiens] 108
413841 M34276 Hs 75576 plasminogen 107
429201 X03178 Hs 198246 group-spxific component (vitamin D bind 107
433313 W20128 Hs 296039 ESTs 107
439450 R51613 Hs 125304 ESTs 107
458963 AI701393 Hs 278728 Rad and Gem related 2 (rat homolog) 107
405161 106
406741 AA058357 Hs 74466 carcmoembryonie antigen related cell ad 106
424294 BE299311 gb 601119256F1 NIH_MGC_17 Homo sapiens c 106
424544 M88700 Hε 150403 dopa dxarboxylase (aromatic L-ammo xi 106
444687 AW972109 Hs 135107 ESTs 106
444754 T83911 Hs 11881 transmembrane 4 superfamily member 4 106
421243 AW873803 Hs 102876 pancreatic lipase 105
.444290 AA262496 Hs 29280 ESTs 105
407984 AW134708 Hs 243569 ESTε 104
439706 AW872527 Hs 59761 ESTε 104
402194 103
427506 AK000134 Hε 179100 hypothetical protein FLJ20127 103
428819 AL135623 Hs 193914 KIAA0575 gene product 103
434590 T47232 gb yb64b08 s1 Stratagene ovary (937217) 103
416378 AW044467 Hs 73708 ESTs Weakly similar to A57291 cytokine 102
431912 AI660552 Hs 154903 ESTs, Weakly similar to A56154 Abl subst 102
443316 AI478463 Hs 18443 ESTs 102
428585 AB007863 Hs 185140 KIAA0403 protein 101
400440 X83957 Hs 83870 nebulin 100
404619 BE514535 Hs 77171 minichromosome maintenance deficient (S 100
407168 R45175 gb yg40f01 s1 Soares infant brain 1NIB H 100 408052 AW501117 Hs 283585 ESTs 1 00
409187 AF154830 Hs 50966 carbamoyl phosphate synthetase 1, mitoch 1 00
409327 L41162 Hs 53563 collagen, type IX alpha 3 1 00
410234 NM.003837 Hs 61255 fructose 1,6 bisphosphatase 2 1 00
410319 R23413 Hs 71935 putative zinc finger protein from EUROIM 1 00
411000 N40449 Hε 201619 ESTs, Weakly similar to SEB4B [H sapiens 1 00
412098 AI493054 Hs 158968 ESTs 1 00
412446 AI768015 Hs 92127 ESTs 1 00
412637 AA115097 Hs 261313 ESTs 1 00
413147 BE067271 gb PM2 BT0349 161299001 b05 BT0349 Homo 1 00
413597 AW302885 Hs 117183 ESTs 1 00
414117 W88559 Hs 1787 proteolipid protein (Pelizaeus Merzbxhe 1 00
414523 AU076633 Hs 76353 senne (orcyεteine) proteinase inhibito 1 00
417074 Z49878 Hs 81131 guanidinoacetate N methyltransferaεe 1 00
418390 AF133820 Hs 84665 titin immunoglobulin domain protein (myo 1 00
419768 T72104 Hs 93194 apolipopratem A I 1 00
420182 Z44245 Hs 22999 ESTε 1 00
420923 AF097021 Hs 273321 differentially expreεsed in hematopoieti 1 00
421100 AW351839 Hs 124660 Homo sapiens cDNA FLJ21763 fis, clone C 1 00
421204 AW081587 Hs 165051 ESTs 1 00
422189 AF252292 Hs 112933 Tax interaction protein 40 1 00
422792 AI951548 Hs 135163 ESTs 1 00
423371 AU076819 Hs 1650 solute earner family 26, member 3 1 00
424208 AW583123 Hε 143113 pancreatic lipase related protein 2 1 00
424922 BE386547 Hε 217112 ESTs, Weakly similar to Similarity to Ye 1 00
425206 NM.002153 Hs 155109 hydroxysteroid (17 beta) dehydrogenase 2 1 00
425545 N98529 Hs 158295 Human mRNA for myosin light chain 3 (MLC 1 00
425983 AK000226 Hs 165619 mucin and cadhenn like 1 00
426004 AW600300 Hs 124123 ESTs, Weakly similar to syncol n [R nor 1 00
427627 R87582 Hs 179915 guanine nucleotide binding protein (G pr 1 00
428848 NM 000230 Hs 194236 leptin (munne obesity homolog) 1 00
429027 AL022314 Hs 194750 Human DNA sequence from clone 1170K4 on 1 00
429231 AA813214 gb aj32e09 s1 Soares.testis.NHT Homo sap 1 00
429441 AJ224172 Hs 204096 lipophilin B (uteroglobin family member) 1 00
429930 AI580809 Hs 99569 ESTs 1 00
429970 AK000072 Hs 227059 chloride channel, calcium xtivated, fam 1 00
430418 R98852 Hs 36029 heart and neural crest derivatives expre 1 00
431845 AA516469 Hs 270554 ESTs 1 00
433084 M18079 Hs 282265 fatty acid binding protein 2, intestinal 1 00
433839 F35430 Hs 146070 ESTs, Weakly similar to ALU1 HUMAN ALU S 1 00
434452 AA634333 Hs 116822 ESTs 1 00
435499 R89344 Hs 14148 ESTs 1 00
438433 AB018274 Hs 6214 KIAA0731 protein 1 00
442403 AW207724 Hs 129516 ESTs 1 00
442803 AI675298 Hs 199917 ESTs 1 00
443266 AI277101 Hs 25890 ESTs, Weakly similar to transducm [H sa 1 00
444656 AI277924 Hs 145199 ESTs 1 00
445573 AI439646 Hs 157494 ESTs, Weakly similar to KIAA0676 protein 1 00
446163 AA026880 Hs 25252 Homo sapiens cDNA FU13603 fis, clone PL 1 00
447359 NM.012093 Hε 18268 adenylate kinase 5 1 00
447551 BE066634 Hs 929 myosin, heavy polypeptide 7, cardix mus 1 00
448657 BE147857 Hs 293841 ESTs, Weakly similar to KIAA0672 pratem 1 00
449238 AA428229 Hs 85524 muscle-spxific RING-finger protein homo 1 00
450085 AW293791 Hs 60162 Homo sapiens cDNA FU21528 fis, clone C 1 00
450390 N93227 Hs 98403 ESTs 1 00
451681 Z28564 Hs 255950 ESTs, Weakly similar to AA64 HUMAN 64 KD 1 00
452093 AA447453 Hs 27860 Homo sapienε mRNA, cDNA DKFZp586M0723 (f 1 00
452528 AA742457 Hs 291479 ESTs 1 00
452624 AU076606 Hs 30054 coagulation fxtor V (proxceleπn, labi 1 00
453754 AW972580 Hs 172753 ESTs 1 00
453991 AW014915 Hs 273741 ESTs 1 00
454517 AW803340 gb IL2-UM0079-090300-050-D02 UM0079 Homo 1 00
459367 BE148877 gb CM4-HT0244-111199 040-h12 HT0244 Homo 1 00
408021 AW137133 Hε 245867 ESTs 099
417435 NM 005181 Hs 82129 carbonic anhydrase III, muscle specific 099
437206 AW975934 Hs 283382 ESTs, Weakly similar to Protein sequence 099
422890 Z43784 Hs 78713 εolute carrier family 25 (mitochondnal 098
425878 AW964806 Hs 38085 ESTε, Weakly similar to putative glycine 098
441888 AI733306 Hε 128071 hypothetical protein FLJ21302 098
423068 M25629 Hs 123107 kallikrein 1, renal/pancreas/salivary 097
453534 NM 014796 Hs 33187 KIAA0748 gene product 097
457787 AA683268 gb ae92b04 s1 Stratagene εchizo brain S1 097
421285 NM 000102 Hs 1363 cytxhrome P450, εubfamily XVII (steroid 096
422069 AJ010063 Hs 111110 titm-cap (telethoniπ) 096
425260 L47726 Hs 1870 phenylalanine hydroxylaεe 096
418406 X73501 Hs 84905 cytokeratin 20 095
425670 AW968536 Hs 190146 ESTε 095
416373 AA195845 Hs 73680 ESTs, Weakly similar to AF198455 1 epith 094
452243 AL355715 Hs 28555 programmed cell death 9 094
411908 L27943 Hs 72924 cytidme deammase 093
415067 AI264969 Hs 929 myosin heavy polypeptide 7, cardix mus 093
437156 AI916600 Hs 121194 Homo sapiens cDNA FLJ21569 fis clone C 093
450685 L15533 Hs 423 pancreatitis associated protein 092 427450 AB014526 Hs 178121 KIAA0626 gene product 091
432440 X63597 Hs 2996 sucrase isomaltase 091
426651 AU076646 Hs 171683 nuclear receptor subfamily 1, group H, m 090
414910 X12662 Hs 29679 cofactor required for Sp1 transcπptiona 089
423317 AJ272204 Hs 64616 chromosome 12 open reading frame 3 089
424735 U31875 Hs 152677 Homo sapiens cDNA FLJ20338 fis clone HE 089
439751 AA196090 Hs 50794 Homo sapiens mRNA full length insert cDN 089
452689 F33868 Hs 284176 transferrin 089
446240 AI535736 Hs 170165 ESTs 0 88
449110 H56112 Hs 277053 ESTs 088
453817 AW755253 Hs 61920 ESTs 088
428221 U96781 Hs 183075 ESTs, Highly similar to Ca2+ ATPase off 087
438461 AW075485 Hs 286049 phosphoεeπne ammotransferase 087
446525 AW967069 Hs 211556 Homo sapiens cDNA FLJ23378 fis, clone H 087
453341 AI758912 Hs 296341 adenylyl cyclase-ass∞iated protein 2 087
403740 086
420156 AW449258 Hs 6187 ESTs 086
430304 AL122071 Hs 238927 Homo sapiens mRNA, cDNA DKFZp434H1235 (f 086
421142 AW503944 Hs 130822 ESTs 085
444107 T46839 Hs 10319 UDP glycosyllransferase 2 family, polype 085
419415 AW451692 Hs 192036 ESTs 0 84
423321 AB013885 Hs 126926 beta-ureidopropionase 084
432938 T27013 Hs 3132 steroidogenic acute regulatory protein 0 84
433447 U29195 Hs 3281 neuronal pentraxm II 084
403047 083
406707 S73840 Hs 931 myosin, heavy polypeptide 2, skeletal mu 081
407782 AA608956 Hs 112619 ESTs, Weakly similar to PQ0109 Purkinje 081
405232 080
437776 AA768037 Hs 291671 ESTs 0 80
415505 R39870 Hs 12548 ESTs 079
444436 N25871 Hs 177337 ESTs 078
409096 AA194412 Hs 50550 sarcomeπc muscle protein 077
432134 AI816782 Hs 122583 Homo sapiens cDNA FLJ21934 fis, clone H 076
437066 AA743570 Hs 200935 ESTs 076
427003 U19487 Hs 2090 prostaglandin E receptor 2 (subtype EP2) 075
423634 AW959908 Hs 1690 hepaπn binding growth fxtor binding pr 073
413333 M74028 Hε 75297 fibroblast growth fxtor 1 (acidic) 071
420567 AK000812 Hs 98874 similarto proline πch protein 48 071
447145 AA761073 Hs 192943 ESTs 071
452103 R42764 Hs 3248 mutS (E coli) homolog 6 071
410929 H47233 Hs 30643 ESTs 070
400301 X03635 Hs 1657 estrogen receptor 1 069
415702 F28877 gb HSPD18414 HM3 Homo sapiens cDNA clone 067
411396 C04646 Hs 85428 ESTs 0 65
431706 AI816086 Hs 296341 adenylyl cyclase assxiated protein 2 065
TABLE 28B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT number Accession
407743 1012151.1 AW814118 AW814257 AW072376
408123 1040435 1 AW163377 AW160398
408432 1058667 1 AW195262 R27868AW811262
408664 1073340 1 R56362 AW248096 R07152 R07285
408922 109017 1 R87388 R84328 AA058916
409368 112377 1 AA071059 AA085201 AA085020
409543 1138723 1 AW410200 AW409705 AW411433 BE296786 BE270309
409689 114833 ϊ AA078492 AA078333 AA077450 AA077746 AA076896
409778 1154206 1 AW499705 AW502537 AW503016
409802 1155179 1 AW500732AW504061
410285 119128 1 AA083609 AA083790 AA112048
410881 1225682.1 AW809157 AW812181 AW812175 AW812172 AW812161 AW812165
411187 1235092 1 AW821291 AW821264AW821287 AW821290 AW821285AW821280AW821259
412067 1275641 1 N45697 N45540 AW890595
413147 1350637 1 BE067271 BE067266 BE067286 BE067278 BE067299 BE067285
413242 1355323 1 BE074165 BE075001 BE075009
413811 1391117.1 BE168828 BE168830 BE168823 BE168928 BE168820 BE168826
414060 1413697 1 BE246327 BE244704
414095 1416521 1 BE293546 BE249848
414160 1422273 1 BE257021 BE258316 BE257099
414580 1463848 1 BE386918 BE408833 BE385437
415011 151328 ϊ AW963085 AA159005 AW963073
415566 153986? 1 F12119 Z45475T64832
415702 1547874 1 F28877 F35687
417998 171375 1 AW967420AA210915 AA236991 AA210916
418197 172864 1 AA214253 AA214259 Z28472 Z28881 Z17828
418464 1759038 -2 R87580
418556 1767866 -1 T02850 422619 2186701 AA313322 BE408282 AA465612 BE073382
422796 221500J AW897265 AW897274 AL119504 AW897275 AW897270 AW897312 AW897318 AW897317 AA317240 AW961361 T06241 AA326794 AL138130
AW407975AW999277
424294 2379071 BE299311 AA338954 AA338468 AW960907
424334 238221.1 AA393460 AA338940 AW966277 AA419006
424648 2419471 AA344576 AA732430 AA344601
425515 252721 1 W26609 W27360AA358818
426328 2649011 AW631296AA375484
426507 268382.1 AA380285 AW934727 AW934914
426755 2713821 BE253469 BE176417 BE176415 AA384133
426880 2732772 AA453482AF012388
426998 274259 -1 BE274360
429231 3014631 AA813214 A1936567 AI743529 AA448279 AA994476 AI807452 AI218180 AA972858
430728 3227061 AW968522 AA485112 AA485162 AW968698
432092 341241 AF135026 AA583908
433114 359041 AA121579 AB005217
434590 38931 1 T47232 AF147365T47231
437237 43506 -2 BE513073
437728 4415201 AA766719 AA767041 AW977440
439894 4787381 AA853077AA852175
442197 5355501 AW837912 AW837934 AA984475 AW997490
442614 5470731 AI269030 AI204085 AI004047
444475 6078741 C75571 AI150469T10778
448427 7629701 BE395260 AW291036 AI500420
449329 804841 AW752783 H38266AA001166
451588 876671 AW072057 AI225096 AA018702
452456 918391 1 BE080763 T96699 BE081135 AI902630 H49182 AI904021 AI902697
454517 12210631 AW803340 AW803280 AW803275 AW803415 AW803343 AW803422
454748 12330131 AW862014 AW858740 AW858735 AW818542 AW858765 AW862027 AW858775 AW858771 AW858763
454869 1238137.1 AW836004 AW836087 AW836163 AW836162 AW836085 AW836084 AW836079 AW836083 AW836082 AW836086 AW836088 AW836166 AW836164
AW836002AW836078AW836161 AW862135AW836165 AW836003
454886 12389871 AW837063 AW935882 AW935957
455075 12523891 AW854850AW854848
455104 1253737.1 BE064863 BE153698 AW856751 BE153820 BE064737 BE153674 BE064730 BE065062 BE153536 AW856622 BE155079 BE064651 BE153665
BE064650 BE064691
455366 12846851 AW947563 AW947543 AW947553 AW947549 AW947717 AW902859 AW902927 BE011032
455433 1290311 1 AW939463 AW939484 AW939480 AW939459 AW939546 AW939593 AW939548 AW939595 AW939106
455446 12919691 AW947749 AW947746 AW947754 AW946636 AW946674
455579 1333944.1 BE011320 BE006381 BE006361 BE011180 BE011328 BE011325 BE011157 BE006384 BE006387 BE006385 BE011160 BE011319 BE011346
BE006370 BEO06386 BE011173 BE006389 BE006376 BE006375 BE006364 BE011321 BE006379
455652 13487361 BE064675 BE064761 BE064809 BE064673 BE064672 BE064674
455817 1371986.1 BE142384 BE142387
455994 1398737.1 BE179190 BE179206 BE179182 BE179185 BE179186 BE179194
456150 15743951 Z42308 H23514
456379 18391132 W22206 W22498W26922
456387 18427301 W28876W26158
456702 219191 1 AI684534BE262411 AA314031 AW752724
457416 3345031 BE142052 AW265588 AA506741
457787 4072351 AA683268 BE002903 BE002672
458764 73207.1 BE619386AA300687
459197 9242291 BE244587 AW938684 AW176490 AI940102 AW844995 AW938670 AI909850 AI909885 AI940079 AI909873
TABLE 28C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide poεitionε of predicted exonε
Pkey Ref Strand NLposition
400489 8954013 Plus 131475-131652 400527 9796886 Plus 160750-161007
400545 9800107 Minus 124618-124881
400624 7228177 Minus 94097-94756
400635 8567750 Minus 102800-102932,107482-107689
400672 8118724 Minus 148067-148503 400675 8118750 Plus 11223-11816
400694 8118802 Plus 94288-94442
400736 8118985 Plus 143447-143851
400846 9188605 Plus 39310-39474
401007 8117333 Minus 140821-141050 401015 8117441 Plus 72260-72369
401039 7232177 Plus 6588-6884
401122 8570296 Plus 68256 68444
401238 9954455 Minus 49473-49644
401442 8346725 Minus 85674-85910 401496 7381769 Minus 82790-83002
401590 9966320 Minus 33547-33649
401603 7689963 Minus 116659 116780
401624 8575907 Plus 168318-168444,172964-173647 401688 2347081 Plus 22016-22624
401704 3097841 Plus 24712-25374
401728 8134856 Minus 82117-82920
401743 2865207 Plus 115475115640
401767 9958312 Plus 156823-156921,157364-157554
401810 7342191 Plus 129063-129476
401840 7684597 Plus 56283-56439
401886 7229913 Minus 79215-79393
401919 9502466 Plus 67536-67666
401969 3126777 Plus 44863-45366
402051 8082020 Minus 19346-19480,20041-20119
402056 8084234 Pluε 207002-207288
402153 8247879 Minuε 122580-122987
402158 8516165 Minus 148298-148429,148566-148677
402165 8569830 Minus 65064-65979
402194 8576113 Plus 70917-71191
402195 7689778 Minus 147901-148884
402201 8576119 Plus 655-951
402316 7527774 Minus 10751-10919,18817-19052,22131-22328
402382 9690314 Minus 155331-155528
402386 9799769 Plus 22069-22303
402394 9929690 Plus 33308-33482
402409 9796255 Minus 8571-10061
402423 9796344 Minus 62487-62664
402448 9796640 Plus 112942-113069,114303-114521
402457 9796782 Minus 16513-16577,16838-16926
402534 9801061 Plus 58989-59457
402538 9801137 Minuε 96314-96539
402561 9864675 Plus 72967-73163
402588 9908948 Minus 33027-33183,59060-59198
402690 8348058 Plus 13368-13998
402714 8969253 Minus 18811-18886,19105-19328,19525-19764
402762 9230904 Minus 123298-124035
402862 2956660 Minus 18518-18656
402911 7263904 Plus 142689-142979
402951 9408717 Plus 73252-73329,73718-73877,76217-76299,78195-78401
402968 9581763 Minus 58658-58924
403047 3540153 Minus 59793-59968
403115 7331404 Minus 142952-143094,145474-145653,146269-146445,152816-152998
403125 9180936 Minus 197548-197712
403183 9838273 Plus 109930-110074
403186 9838287 Minus 117513-117856
403211 7630841 Minus 159211-159369
403247 7656833 Minus 76626-77140
403251 7677983 Plus 100391-100652
403327 8440025 Minus 174311-174451,174587-174705,175523-175592
403376 9369545 Minus 108698-108830
403479 7329292 Minus 148369-148533,150678-150809
403526 8017144 Plus 55367-55483
403540 8077057 Minus 56315-56450
403605 6862654 Plus 91614-91718
403612 8469060 Minus 94723-94859
403665 7249278 Plus 69027-69375
403716 7239669 Plus 86899-87122
403731 7543752 Minus 144000-144618
403740 7630882 Plus 86504-87227
403921 7711590 Minus 3297-3536
403942 7711825 Minus 99606-99757
403997 7708819 Plus 134427-134593
404139 9838113 Plus 76707-76891
404247 7406725 Minus 83949-84214,84312-84415,84499-84677,84878-85114
404282 2276311 Plus 61503-62205
404348 7630858 Minus 28895-29062
404668 9797204 Minus 11332-11546,12584-12718
404682 9797231 Minus 40977-41150
404795 4826439 Plus 147501-147780
404825 6478944 Plus 210382-210494
404938 7381808 Minus 165838-165950
405075 7770506 Minus 124680-125321
405147 9438278 Minus 158996-159557
405161 9966260 Plus 157607-157785
405163 9966267 Minus 161171-161299
405187 7229826 Plus 117025-117170,118567-118736
405217 7239551 Plus 32646-33138
405232 7249042 Plus 125904-126063
405243 7249201 Minus 22312-23197
405327 6094661 Minus 120550-120750
405378 6491714 Plus 9113991440
405420 7211837 Minus 13428-13582
405703 4240388 Minus 15850-16061
405737 9943984 Minus 104275-104508,104755-104877
405895 7677903 Minus 66990-67484
406059 9103984 Minus 13856-14004 406101 9124019 Plus 125325-125831
406118 9143818 Plus 53997-54629
406150 9886026 Minus 59331-59701
406158 7144874 Plus 62393 63016,65012 65578
406343 9255974 Plus 17284-17440,18489-18646 18917-19004,19384-19538
406357 9256093 Minus 77181 77415
406563 7711604 Plus 34401-34538
TABLE 29A 2286 GENES UP-REGULATED IN IDIOPATHIC PULMONARY FIBROSIS (IPF) COMPARED TO NORMAL BODY
Table 29A lists about 2286 genes that are up regulated in idiopathic pulmonary fibrosis samples as compared with normal "body map" samples These were selxted from about 59680 probeεets on an Affymetnx/Eos Hu03 GeneChip array such that the ratio of "average" idiopathic pulmonary fibrosis expresεion level to "average" normal adult tissues sample expression was greater than or equal to about 20 The "average" fibrosis sample expression level was set to the 90* percentile amongst idiopathic pulmonary fibrosis sampleε The
"average" normal adult tissue level was set to the 95* percentile amongst non malignant tissues In order to remove gene specific bxkground levels of non-specific hybridization, the 15* percentile value amongst non malignant tissueε was subtracted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of IPF to normal body tissue
Pkey ExAccn Unigene ID Unigene Title R1
427383 NM 005411 Hs 177582 surfactant, pulmonary associated protein 211 8
442275 AW449467 Hs 54795 ESTs 1897
431433 X65018 Hs 253495 surfactant, pulmonary-associated protein 134 1
441835 AB036432 Hs 184 advanced glycosylation end product spxi 1304
417204 N81037 Hε 1074 εurfactant, pulmonary-assxiated protein 1168
421798 N74880 Hs 264330 N-acylsphingosme amidohydrolase (acid c 921
406964 M21305 gb Human alpha satellite and satellite 3 807
443709 AI082692 Hε 134662 ESTs 67 1
431164 AA493650 Hs 94367 Homo sapienε cDNA FLJ23494 fiε, clone L 61 4
445537 AJ245671 Hs 12844 EGF-like-domam, multiple 6 574
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial 546
457200 U33749 Hs 197764 thyroid transcnption fxtor 1 449
432519 AI221311 Hs 130704 ESTε, Weakly similar to BCHUIA S-100 pro 427
443324 R44013 Hs 164225 ESTs 39 8
414142 AW368397 Hs 150042 Homo sapiens cDNA FLJ14438 fis, clone HE 273
442006 AW975183 Hs 292663 ESTs, Weakly similar to S72482 hypotheti 27 1
444527 NM.005408 Hs 11383 small inducible cytokine subfamily A (Cy 27 1
453310 X70697 Hs 553 solute ca erfamily 6 (neurotransmitte 269
424084 AI940675 Hs 20914 hypothetical protein FLJ23056 222
421659 NM 014459 Hs 106511 protocadhenn 17 21 0
450478 AW451709 Hs 271200 ESTs 202
444342 NM 014398 Hs 10887 similar to lysosome assxiated membrane 197
447033 AI357412 Hs 157601 ESTs 194
445885 AI734009 Hs 127699 KIAA1603 protein 189
411880 AW872477 gb hm30f03 x1 NCI CGAP_Thy4 Homo sapiens 179
432437 W07088 Hε 293685 ESTs 178
424105 AI142336 Hε 43977 Human DNA sequence from clone RP11-196N1 17 3
431941 AK000106 Hs 272227 Homo sapiens cDNA FLJ20099 fis, clone CO 172
440807 AW269421 Hε 128093 ESTs 167
424917 AI636208 Hs 96901 hypothetical protein FU23049 164
433365 AF026944 Hs 293797 ESTs 164
445279 R41900 Hs 22245 ESTs 164
417801 AA417383 Hs 82582 integnn, beta like 1 (with EGF-like rep 164
405654 161
449328 AI962493 Hs 197647 ESTs 16 1
449494 AW237014 Hs 315369 Homo sapiens cDNA FLJ23075 fis, clone L 157
408826 AF216077 Hs 48376 Homo sapiens clone HB-2 mRNA sequence 15 5
417728 AW138437 Hs 24780 KIAA1573 protein 150
440452 AI925136 Hs 55150 ESTs, Weakly similar to CAYP HUMAN CALCY 148
452039 AI922988 Hs 172510 ESTε 144
408771 AW732573 Hs 47584 potassium voltage-gated channel, delayed 143
421464 AA291553 Hs 190086 ESTs 14 1
421554 AW137676 Hs 97775 ESTs 138
431889 AA521277 Hs 124946 ESTs, Weakly similar to A46010 X-lmked 132
434424 AI811202 Hs 325335 Homo sapiens cDNA FLJ23523 fis, clone L 132
431924 AK00O85O Hs 272203 Homo sapiens cDNA FLJ20843 fis, clone AD 129
459702 127
421110 AJ250717 Hs 1355 cathepεin E 126
407638 AJ404672 Hs 334483 hypothetical protein FLJ23571 126
423575 C18863 Hs 163443 Homo εapienε cDNA FLJ11576 fiε, clone HE 125
423244 AL039379 Hs 209602 ESTs, Weakly similar to ubiquitous TPR m 122
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph 12 1
436982 AB018305 Hs 5378 spondm 1, (f-spondin) extracellular mat 121
451561 N52812 Hs 177403 ESTs 120
424086 AI351010 Hs 102267 lysyl oxidase 120
435299 AI745458 Hs 122614 ESTs, Weakly similar to T20593 hypotheti 120
429496 AA453800 Hs 192793 ESTs 11 9 432365 AK001106 Hs 274419 hypothetical protein FLJ10244 11 9
403637 11 2
436061 AI248584 Hs 190745 Homo sapiens cDNA FLJ21326 fis, clone C 11 2
431385 BE178536 Hs 11090 membrane spanning 4 domains, subfamily A 10 9
421470 R27496 Hs 1378 annex A3 108
440209 H05049 Hs 22269 neurexm 3 10 8
428927 AA441837 Hs 90250 ESTs 107
448693 AW004854 Hs 228320 hypothetical protein FLJ23537 10 5
424717 H03754 Hs 152213 wingless type MMTV integration site farm 104
416402 NM 000715 Hs 1012 complement component 4-bιndmg protein, 104
446998 N99013 Hs 16762 Homo sapiens mRNA cDNA DKFZp564B2062 (f 104
442176 AA983764 Hs 128910 ESTs 104
439606 W79123 Hs 58561 G protein coupled receptor 87 103
452883 X80031 Hs 530 collagen, type IV, alpha 3 (Goodpasture 103
417015 M83772 Hs 80876 flavin containing monooxygenase 3 103
422022 AA302420 Hs 200442 ESTs 103
447724 AW298375 Hs 24477 ESTs 102
406671 AA129547 Hs 285754 met proto-oncogene (hepatocyte growth fa 100
458194 AW383618 Hs 265459 ESTs, Moderately similar to ALU2_HUMAN A 99
446232 AI281848 Hs 194691 retinoic xid induced 3 99
416208 AW291168 Hs 41295 ESTs, Weakly similarto MUC2.HUMAN MUCIN 99
453382 AA709285 Hs 5997 hypothetical protein FLJ13078 98
412372 R65998 Hs 285243 hypothetical protein FLJ22029 98
426830 AA385751 Hs 196379 ESTs, Weakly similar to putative p150 [H 98
407568 AA740964 Hs 62699 ESTs 98
414259 W44633 Hs 301296 Homo sapiens cDNA FLJ23131 fis clone L 96
400289 X07820 Hs 2258 matnx metalloprotemase 10 (stromelysin 95
441484 AA935481 Hs 58972 ESTs 95
422426 W79117 Hs 58559 ESTs 94
406747 AI925153 Hs 217493 annexm A2 94
450050 A1681268 Hs 257883 ESTε 94
431337 N48107 Hs 292593 ESTε 93
408427 AW194270 Hs 177236 ESTs 93
447048 AW393080 Hs 228320 hypothetical protein FLJ23537 93
453636 R67837 Hs 169872 ESTs 93
443450 N66045 Hs 133529 ESTs 92
418735 N48769 Hs 44609 ESTs 92
421160 AL080215 Hs 102301 Homo sapiens mRNA, cDNA DKFZp586J0323 (f 9 1
449802 AW901804 Hs 23984 hypothetical protein FU20147 9 1
441233 AA972965 Hs 135568 ESTs 9 1
459587 AA031956 gb zk15e04 s1 Soares_pregnanLuterus_NbH 90
436246 AW450963 Hs 119991 ESTs 90
445189 AI936450 Hs 147482 ESTs 89
410781 AI375672 Hs 165028 ESTs 89
446868 AV660737 Hs 135100 ESTs
415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t
425664 AJ006276 Hs 159003 transient rxeptor potential channel 6
414968 C16096 Hs 22826 trapomodulin 3 (ubiquitous)
410334 AW979261 Hs 291993 ESTs
442510 AF150179 Hs 249890 ESTs
409238 AL049990 Hs 51515 Homo sapienε mRNA, cDNA DKFZp564G112 (fr 87
431089 BE041395 Hs 283676 ESTs, Weakly similar to unknown protein 87
444929 AI685841 Hs 161354 ESTs 87
413802 AW964490 Hs 32241 ESTε, Weakly similar to S65657 alpha-1 C- 86
444218 AF070641 Hs 10684 Homo sapiens clone 24421 mRNA sequence 86
412719 AW016610 Hs 129911 ESTs 86
453445 AL036532 Hs 91453 ESTs 85
419261 X07876 Hs 89791 wingless-type MMTV integration site fami 85
451110 AI955040 Hs 265398 ESTs, Weakly similar to transformatton-r 85
433815 AI696602 Hs 112757 ESTs 83
432203 AA305746 Hs 49 mxrophage scavenger rxeptor 1 83
451103 R52804 Hs 25956 DKFZP564D206 protein 83
425921 NM 007231 Hs 162211 solute camerfamily 6 (neurotransmitte 83
424989 AA985520 Hs 23575 ESTs 83
433231 AB040926 Hs 143552 KIAA1493 protein 82
408217 AI433201 Hs 279860 tumor protein, translationally-controlle 8 1
431806 AF186114 Hs 270737 tumor nxrosis factor (ligand) superfami 81
436751 AA732217 Hs 294054 ESTs 80
452891 N75582 Hs 212875 ESTs, Weakly similar to DYH9.HUMAN CILIA 80
413048 M93221 Hs 75182 mannose receptor, C type 1 80
426803 AA362568 Hs 179747 xotropic viral integration site 5 79
409718 D86640 Hs 56045 src homology three (SH3) and cysteine n 78
423424 AF150241 Hs 128433 prostaglandin D2 synthase, hematopoietic 78
429597 NM 003816 Hs 2442 a disintegnn and metalloproteinase doma 77
421013 M62397 Hε 1345 mutated in colorectal cancers 77
437479 R61866 Hs 101277 ESTs 76
416778 M16505 Hs 79876 steroid sulfatase (microsomal), arylsulf 76
421478 AI683243 Hs 97258 ESTs, Moderately similar to S29539 πbos 76
444396 T65213 Hs 4257 ESTs 76
423629 AW021173 Hs 18612 Homo sapiens cDNA FLJ21909 fis, clone H 76
450715 AI266484 Hs 31570 ESTs, Weakly similarto KIAA1324 protein 76
445495 BE622641 Hs 38489 ESTs, Weakly similar to I38022 hypotheti 76
446466 H38026 Hs 308 arrestin 3, retinal (X arrestin) 76 449108 AI140683 Hs 98328 hypothetical protein MGC13040 75
422798 R92347 Hs 34574 ESTs, Weakly similar to ALU1 HUMAN ALU S 75
416030 H15261 Hs 21948 ESTs 75
426486 BE178285 Hs 170056 Homo sapiens mRNA, cDNA DKFZp586B0220 (f 74
424906 AI566086 Hs 153716 Homo sapienε mRNA for Hmob33 protein, 3' 74
448206 BE622585 Hs 3731 ESTs, Moderately similar to 138022 hypot 73
432133 AB033088 Hs 272567 KIAA1262 protein 73
447112 H17800 Hs7154 ESTs 73
446917 AI347863 Hs 156672 ESTs 73
428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy 73
431761 AW002846 Hε 105468 hypothetical protein FLJ22690 73
428743 AL080060 Hs 301549 Homo sapiens mRNA cDNA DKFZp564H172 (fr 72
413499 BE144884 gb CM0 HT0182-041099 065-e11 HT0182 Homo 72
423909 AJ223183 Hs 135194 immunoglobulin superfamily, member 6 72
438122 AI620270 Hs 129837 ESTε, Weakly similar to Z263 HUMAN ZINC 72
449611 AI970394 Hs 197075 ESTs 72
453616 NM 003462 Hs 33846 dynein, axonemal, light intermediate pol 72
410060 NM.001448 Hs 58367 giypican 4 72
442353 BE379594 Hs 49136 ESTs, Moderately similar to ALU7_HUMAN A 72
452571 W31518 Hs 34665 ESTs 72
453736 AL118674 Hs 34871 zinc finger homeobox 1B 72
409203 AA780473 Hs 687 cytochrome P450, subfamily IVB, polypept 72
405494 72
442832 AW206560 Hs 253569 ESTs 71
420193 AI460080 Hs 202869 ESTs 71
434217 AW014795 Hs 23349 ESTs 70
427356 AW023482 Hs 97849 ESTs 70
436396 AI683487 Hs 152213 wingless-type MMTV integration site fami 69
408308 AL033377 Hs 44197 hypothetical protein DKFZp564D0462 69
442377 AA993807 Hs 167367 ESTs 69
441143 AI027604 Hs 159650 ESTs 69
445122 AW241632 Hs 147377 hypothetical protein FLJ23598 69
431353 AA828032 Hs 189076 ESTs 69
407510 U96191 gb Human trophoblast hypoxia regulated f 68
426753 T89832 Hs 170278 ESTs 68
445186 AW614544 Hs 123641 protein tyrosine phosphatase, rxeptor t 68
451963 AI825440 Hs 224952 ESTs 68
400298 AA032279 Hs 61635 six transmembrane epithelial antigen of 68
433426 H69125 Hs 133525 ESTs 68
434377 AW137148 Hs 306593 Homo sapienε cDNA FLJ11382 fis, clone HE 68
415236 R41400 gb yf94b12 s1 Soares infant brain 1NIB H 68
409031 AA376836 Hs 76728 ESTs 67
427558 D49493 Hs 2171 growth differentiation fxtor 10 67
437259 AI377755 Hs 120695 ESTs 67
421952 AA300900 Hs 98849 ESTs Moderately similar to AF161511 1 H 67
447081 Y13896 Hs 17287 potasεium inwardly-rectifying channel, s 67
430099 AW194988 Hs 20537 hypothetical protein FLJ13942 67
422475 AL359938 Hs 117313 Meiε (mouse) homolog 3 67
413472 BE242870 Hs 75379 solute camerfamily 1 (glial high affi 67
424750 D29956 Hs 152818 ubiquitin specific protease 8 66
403574 66
439759 AL359055 Hs 67709 Homo sapiens mRNA full length insert cDN 66
415025 AW207091 Hs 72307 ESTs 65
448104 AI674818 Hs 316433 Homo sapiens cDNA FLJ 11375 fis, clone HE 65
444271 AW452569 Hs 149804 ESTs 65
437157 BE048860 Hs 120655 ESTs 65
444050 AW138295 Hs 135024 ESTε 65
414569 AF109298 Hs 118258 proεtate cancer assxiated protein 1 65
447505 AL049266 Hs 18724 Homo sapiens mRNA, cDNA DKFZp564F093 (fr 65
424433 H04607 Hs 9218 ESTs 64
407378 AA299264 Hs 57776 ESTs, Moderately similar to I38022 hypot 64
445424 AB028945 Hs 12696 cortxtin SH3 domain-binding protein 64
422544 AB018259 Hs 118140 KIAA0716 gene product 64
449765 N92293 Hs 206832 ESTs, Moderately similar to ALU8_HUMAN A 63
413930 M86153 Hs 75618 RAB11 A, member RAS oncogene family 63
417246 A1760098 Hs 21411 ESTs 63
453652 AW009640 Hs 28368 ESTs, Moderately similar to S65657 alpha 63
411514 AW850178 gb IL3-CT0219-271099022-H12 CT0219 Homo 63
438909 AF085839 gb Homo sapiens full length insert cDNA 63
446002 AI346468 Hs 145789 ESTs 63
419236 AA330447 Hs 135159 Homo sapiens cDNA FU11481 fis, clone HE 63
419150 T29618 Hs 89640 TEK tyrosine kinase, endothelial (venous 63
424202 BE350295 Hs 15032 RAN binding protein 17 63
431723 AW058350 Hs 16762 Homo sapiens mRNA cDNA DKFZp564B2062 (f 62
415511 AI732617 Hs 182362 : ESTS 62
430510 AW162916 Hs 241576 i hypothetical protein PR02577 62
416879 H98899 Hs 42599 ESTs 62
432803 AA565398 gb nk41f01 s1 NCI CGAP GC2 Homo εapieπs 62
442862 BE080429 Hs 15738 ESTs 62
435974 U29690 Hs 37744 Homo sapienε beta-1 adrenergic rxeptor 62
441082 AW444804 Hs 20265! i ESTε 62
404599 61
453931 AL121278 Hs 25144 ESTε 61 420252 AW270404 Hs 193161 ESTs 61
431622 AW979271 Hs 293184 ESTs 61
456964 H59846 Hs 128355 ESTs, Moderately similar to ALU7.HUMAN A 61
415457 AW081710 Hs 7369 ESTs, Weakly similar to ALULHUMAN ALU S 60
424693 BE169810 Hs 47557 ESTs 60
419172 AW338625 Hs 22120 ESTs 60
413384 NM 000401 Hs 75334 exostoses (multiple) 2 60
453037 AA045175 Hs 177552 ESTs 60
444042 NM 004915 Hs 10237 ATP-bmding cassette sub-family G (WHIT 60
431169 AW971240 gb EST383329 MAGE resequences, MAGL Homo 60
422352 AA766296 Hs 99200 ESTs 59
433527 AW235613 Hs 133020 ESTs 59
420077 AW512260 Hs 87767 ESTs 59
429703 T93154 Hs 28705 ESTs 59
433098 AW190593 Hs 151143 ESTs 59
451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 59
449416 AI651016 Hs 246311 ESTs 59
459023 AW968226 Hs 60798 ESTs 59
450584 AA040403 Hs 60371 ESTs 59
427660 AI741320 Hs 114121 Homo sapiens cDNA FLJ 23228 fis, clone C 59
429125 AA446854 Hs 271004 ESTs, Weakly similar to I38022 hypotheti 59
450025 AK001875 Hs 24321 Homo sapiens cDNA FLJ12028 fis, clone HE 59
433479 AW511459 Hs 249972 ESTs 58
443113 AI040686 Hs 132908 ESTs 58
430414 AW365665 Hs 120388 ESTs 58
419752 AA249573 Hs 152618 ESTs, Moderately similar to ZN91JHUMAN Z 58
435420 AI928513 Hε 59203 ESTs 58
404916 58
424310 AA338648 Hε 50334 testeε development related NYD-SP22 58
448253 H25899 Hs 201591 ESTε 58
430899 BE018217 Hs 183528 hypothetical protein FLJ14906 58
446967 AI699629 Hs 156781 ESTε 58
435082 AA664273 Hs 186104 Homo sapiens cDNA FLJ 13803 fis, clone TH 57
438842 AA827176 Hs 124316 ESTs 57
437260 AA747807 Hs 149500 ESTs 57
410934 AW811114 gb MR2-ST0131-111199 016-a04 ST0131 Homo 57
428043 T92248 Hs 2240 uteroglobin 57
408045 AW138959 Hs 245123 ESTs 57
450568 AL050078 Hs 25159 Homo sapiens cDNA FLJ 10784 fis, clone NT 57
428508 BE252383 Hs 184668 SBBI31 protein 57
453393 AW956392 Hs 110376 ESTε 56
444805 AB007899 Hs 12017 homolog of yeast ubiquitin-protein ligas 56
446921 AB012113 Hs 16530 εmall inducible cytokine εubfamily A (Cy 56
429784 M89796 Hs 30 membrane εpanning 4-domaιnε, εubfamily A 56
433225 AW816515 Hs 173540 ATPase, Class V, type 10D 56
416575 W02414 Hs 38383 ESTs 55
404043 55
415094 D59513 Hs 330778 ESTs 55
453049 BE537217 Hs 30343 ESTs 55
430153 AW968128 Hs 336679 ESTs 55
410811 AW805687 Hs 300648 ESTs 55
443903 AI220547 Hs 135223 ESTs 55
429420 AK001679 Hs 202289 hypothetical protein DKFZp434P1735 55
444471 AB020684 Hs 11217 KIAA0877 protein 55
452542 AW812256 gb RCO ST0174-191099-031 -a07 ST0174 Homo 55
434088 AF116677 Hε 249270 hypothetical protein PR01966 55
432113 AA935065 Hs 152385 ESTs 55
446608 N75217 Hs 257846 ESTs 55
419945 AW290975 Hs 118923 ESTε 55
454024 AA993527 Hs 293907 hypothetical protein FLJ23403 54
420209 AA256444 Hs 126485 hypothetical protein FLJ12604, KIAA1692 54
439382 BE247684 Hs 103070 ESTs 54
428895 AA437124 Hs 187247 ESTs 54
446577 AB040933 Hs 15420 KIAA1500 protein 54
419247 S65791 Hs 89764 fragile X mental retardation 1 54
427778 AA412323 Hs 105323 ESTs 54
437138 AI935622 Hs 271245 ESTs 54
431322 AW970622 gb EST382704 MAGE resequences, MAGK Homo 54
430437 AI768801 Hs 169943 Homo sapiens cDNA FLJ13569 fis, clone PL 54
435202 AI971313 Hs 170204 KIAA0551 protein 54
415076 NM 000857 Hs 77890 guanylate cyclase 1, soluble, beta 3 53
434992 AA658501 Hs 283358 ESTs 53
454039 AW079064 Hs 245540 ESTs 53
456408 AI288348 Hs 23450 mitochondnal ribosomal protein S25 53
406554 53
426269 H15302 Hs 168950 Homo sapiens mRNA, cDNA DKFZp566A1046 (f 53
416769 AI339257 Hs 115436 ESTs, Moderately similar to I54374 gene 53
414299 AA142989 Hs 71730 ESTs 53
420362 U79734 Hε 97206 huntingtm interacting protem 1 53
459664 53
425509 AF079363 Hs 158213 l sperm associated antigen 6 53
401497 53
440727 A1073991 Hs 13426E I ESTs, Weakly similar to 2109260A B cell 52 428434 AW363590 Hs 65551 Homo sapiens, Similarto DNA segment, Ch 52 408776 AA057365 Hs 63356 ESTs, Weakly similar to I38022 hypotheti 52 419991 AJ000098 Hs 94210 eyes absent (Drosophila) homolog 1 52 451050 AW937420 Hs 69662 ESTs 52 400297 AI127076 Hs 334473 hypothetical protein DKFZp56401278 52
404957 52
452771 T05477 Hs 333265 ESTs 52 438885 AI886558 Hs 184987 ESTs 52 428244 AI564123 Hs 42500 ADP-nbosylalion factor like 5 52 420481 U50525 Hs 98201 Human BRCA2 region, mRNA sequence CG029 52
455047 AW852530 gb PM1-CT0243 071099 001 g06 CT0243 Homo 52 408729 AA195764 Hs 72639 ESTs 51 457100 AA417878 Hs 48401 ESTs, Moderately similar to ALU8_HUMAN A 51 426342 AF093419 Hs 169378 multiple PDZ domain protein 51 5 417154 AI674701 Hs 21388 ESTs 51
411869 W20027 Hs 23439 ESTs 51 427043 AA397679 Hs 3991 ESTs 51 445635 AI769774 Hs 209831 ESTs, Weakly similar to ALULHUMAN ALU S 51 442973 BE567665 Hs 288550 Homo sapiens cDNA FLJ23156 fis, clone L 51 0 422063 BE156476 gb QV0-HT0368 040100 082-C05 HT0368 Homo 51
448299 AA497044 Hs 20887 hypothetical protein FLJ10392 51 408677 AI279892 Hs 46801 sorting nexm 14 50 404097 50
437636 AA764781 Hs 291844 ESTs 50 5 452822 X85689 Hs 288617 hypothetical protein FLJ22621 50
410733 D84284 Hs 66052 CD38 antigen (p45) 50 439140 W85737 Hs 290830 ESTs 50 407366 AF026942 gb Homo sapiens cιg33 mRNA, partial sequ 50 405547 50 0 423377 AL049377 gb Homo sapiens mRNA, cDNA DKFZp586H0718 50
449168 NM 016206 Hs 23142 colon carcinoma related protein 50 455431 AW938484 gb CM0 DT0057-290200 253-d06 DT0057 Homo 50 452281 T93500 Hs 28792 Homo sapiens cDNA FLJ 11041 fis, clone PL 50 411149 N68715 Hs 269128 ESTs 50 5 432441 AW292425 Hs 163484 ESTs 50
419807 R77402 gb yι75f11 s1 Soares placenta Nb2HP Homo 50 440615 AI733055 Hε 130806 ESTs 50 450109 AI539295 Hs 115740 KIAA0210 gene product 50 . _ 449695 AA164569 Hs 34550 ESTs 50 0 421764 AI681535 Hs 148135 senne/threonine kinase 33 49
404593 49
423607 AA328329 Hs 6591 ESTs 49 432009 AL137424 Hs 306458 Homo εapienε mRNA, cDNA DKFZp761G2123 (f 49 419235 AW470411 Hs 288433 neurotnmin 49 5 436304 AA339622 Hs 108887 ESTs 49
434613 AI821826 gb ns92b10 x5 NCI.CGAP.Pr3 Homo sapiens 49 421502 AF111856 Hs 105039 εolute camerfamily 34 (εodium phospha 49 415245 N59650 Hs 27252 ESTs 49 428780 AI478578 Hs 50636 ESTs 49 0 406333 49
445034 AW293376 Hs 143659 ESTs 48 440202 AW516211 Hs 125300 nng finger protein 21 , interferon-respo 48 424638 AI472106 Hs 49303 Homo sapienε cDNA FLJ 11663 fis, clone HE 48 451497 H83294 Hε 284122 Wnt inhibitory factor-1 48 5 427652 AI673025 Hs 43874 ESTs, Moderately similar to 154374 gene 48
458722 AA741545 Hε 282832 ESTε, Weakly similar to T24961 hypotheti 48 407327 AA487182 Hs 269414 ESTs, Weakly similar to Z195_HUMAN ZINC 48 411018 AW813428 gb MR3-ST0192010200-210-c05 ST0192 Homo 48 415261 T40928 Hs 8346 ESTs 48 0 453543 AA485425 Hs 48919 Homo sapienε cDNA FLJ11508 fis, clone HE 48
438014 N71183 Hs 121806 Homo sapienε cDNA FLJ11971 fis. clone HE 48 407829 AA045084 Hs 29725 hypothetical protein FLJ13197 48 441006 AW605267 Hs 7627 CGI-60 protein 48 412222 AA528283 Hs 292737 ESTs 48 65 424115 AA335497 Hs 293965 ESTs, Weakly similar to I38022 hypotheti 48
453197 AI916269 Hs 109057 ESTs, Weakly similar to ALU5_HUMAN ALU S 48 439398 AA284267 Hs 221504 ESTs 48 436397 AA715013 Hε 169835 ESTs 48 „n 427535 R29543 Hs 2164 pro-platelet basic protein (includes pla 48
70 410901 AW810001 gb MR4-ST0124-270300005-b11 ST0124 Homo 48
425916 NM.006786 Hs 162200 uroteπsm 2 48 447020 T27308 Hs 16986 hypothetical protein FLJ11046 48 427457 AW779105 Hs 164682 ESTs 47 451620 AW449888 Hs 257224 ESTs 47 75 408938 AA059013 Hs 22607 ESTs 47
420036 R60336 Hs 52792 Homo sapiens mRNA, cDNA DKFZp586l1823 (f 47 424508 AL080103 Hs 149770 Homo sapiens cDNA FLJ13658 fis, clone PL 47 430345 AK000282 Hs 239681 hypothetical protein FLJ20275 47 o rv 427669 AW451832 Hs 255938 ESTs, Moderately similar to KIAA1200 pro 47
80 417181 L10123 Hε 1071 surfxtant protein A binding protein 47
435347 AW014873 Hs 116963 ESTs 47 425458 H89317 Hs 182889 ESTε 47 432869 AW974094 gb EST386197 MAGE resequences, MAGM Homo 47 436594 AI419982 Hs 156189 ESTs 47
421237 U25029 Hs 102761 Human glucxorticoid receptor alpha mRNA 47
432731 R31178 Hs 287820 fibronxtin 1 47
419750 AL079741 Hs 183114 Homo sapiens cDNA FLJ14236 fis, clone NT 7
426320 W47595 Hs 169300 transforming growth factor, beta 2 47
419751 AW195581 Hs 93121 KIAA0761 protein 46
433515 AA595800 Hs 190246 ESTε 46
451381 BE241831 Hs 172330 hypothetical protein MGC2705 46
452784 BE463857 Hs 151258 hypothetical protein FLJ21062 46
438297 AW515196 Hs 258238 ESTs, Moderately similar to ALULHUMAN A 46
406992 S82472 gb beta -pol=DNA polymerase beta {exon a 46
431291 N25521 Hs 25275 Kruppel type zinc finger protein 46
435933 AA805520 Hs 192075 ESTs 46
447997 H00656 Hs 29792 ESTs, Weakly similar to I38022 hypotheti 46
445657 AW612141 Hε 279575 Homo sapiens G-pratem coupled receptor 46
426985 BE394849 Hs 131905 ESTs, Moderately similarto Z195 HUMAN Z 46
447700 AI420183 Hs 171077 ESTs, Weakly similar to T21259 hypotheti 46
423735 AA330259 gb EST33963 Embryo, 12 week II Homo sapi 46
424144 AA454033 Hε 41644 AKAP-assxiated sperm protein 46
416258 N45661 Hs 90011 adenylosuccinate synthase 46
410011 AB020641 Hs 57856 PFTAIRE protein kinase 1 46
454359 N71277 gb za36e03 s1 Soares fetal liver spleen 45
422977 AA631498 gb np83h04s1 NCI.CGAP.Thyl Homo sapiens 45
433485 AI493076 Hs 201967 aldo keto redudase family 1, member C2 45
450192 AA263143 Hs 24596 RAD51-ιnteractιng protein 45
432015 AL157504 Hs 159115 Homo sapiens mRNA, cDNA DKFZp586O0724 (f 45
407266 AJ235664 gb Homo sapiens mRNA for immunoglobulin 45
409041 AB033025 Hs 50081 KIAA1199 protein 45
434265 AA846811 Hs 130554 Homo sapiens cDNA FU23089 fis, clone L 45
452526 W38537 Hs 280740 hypothetical protein MGC3040 45
403271 45
450656 AA010539 Hε 18912 ESTs 45
446096 AI276454 gb ql71a12 x1 Soares_NhHMPu_S1 Homo sapi 45
454036 AA374756 Hε 93560 Homo sapiens mRNA for KIAA1771 protein, 45
437960 AI669586 Hs 222194 ESTs 45
440862 H39048 Hs 127432 ESTs 45
410615 AW772721 gb W95c01 x1 NCI CGAP Thy8 Homo sapiens 45
413583 AL120806 Hs 5888 ESTs 45
419449 H18417 Hs 57483 Homo sapiens cDNA FLJ14294 fis, clone PL 45
442324 R63578 Hs 28426 ESTs 44
453080 AI423056 Hs 23921 hypothetical protein DKFZp547A023 44
435747 AI079519 Hs 134398 ESTs 44
446509 AF169693 Hs 132892 protxadherin 20 44
448030 N30714 Hs 325960 membrane spanning 4-domaιns, subfamily A 44
414998 NM.002543 Hs 77729 oxidised low density lipoprotein (Ixtin 44
448089 AI467945 Hs 173696 ESTs 44
434367 ABO2O700 Hs 3830 KIAA0893 protein 44
434757 AI038997 Hs 132921 ESTs 44
413453 AA129640 Hs 128065 ESTs 44
454438 AA224053 Hs 172405 cell division cycle 27 44
458154 AW816379 Hε 335018 ESTs 44
430417 AA461045 Hs 50701 ESTs 44
434819 AA650099 Hε 291541 ESTs, Weakly similar to ALUB.HUMAN mi 44
438796 W67821 Hs 109590 genethonin 1 44
415451 H19415 Hs 268720 ESTs, Moderately similar to ALULHUMAN A 44
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 44
414812 X72755 Hs 77367 monokine induced by gamma interferon 44
451895 T93573 Hs 16970 ESTs 44
435434 AA680387 Hs 187850 ESTs 44
449623 C00719 Hs 120440 EST 44
433563 AI732637 Hs 277901 ESTs 43
444649 AW207523 Hs 197628 ESTs 43
441594 AL041080 Hs 208765 ESTs, Moderately similar to ALU7 HUMAN A 43
443314 AW771701 Hs 54646 ESTs 43
400292 AA250737 Hs 72472 ESTε 43
427872 AA864870 Hs 181304 putative gene product 43
446932 AA961459 Hs 125644 ESTs 43
445640 AW969626 Hs 31704 ESTs, Weakly similar to KIAA0227 [H sapi 43
452393 H87398 Hs 99858 πbosomal protein L7a 43
443204 AW205878 Hs 29643 Homo sapiens cDNA FLJ13103 fis, clone NT 43
400608 43
411156 AW819939 Hs 273629 ESTε 43
435772 AA700019 Hε 132992 ATP-bmding caεsette, sub family G (WHIT 43
439830 AA846666 Hs 151489 ESTs, Weakly similar to XE7 HUMAN PROTEI 43
455511 BE144762 gb CM0 HT0180 041099-065-b04 HT0180 Homo 43
443257 AI334040 Hs 11614 HSPC065 protein 43
436033 H75391 Hs 255748 ESTs 43
420214 AI146375 Hs 286073 ESTs, Moderately similar to ALU5 HUMAN A 43
410519 AW612264 Hs 131705 ESTs 43
401189 43
418852 BE537037 Hs 273294 hypothetical protein FLJ20069 43
425733 F13287 Hs 159388 Homo sapiens clone 23578 mRNA sequence 43
447863 AL047611 Hs 288885 Homo sapiens cDNA FLJ14246 fis, clone OV 43 422429 AA310527 gb EST181333 Jurkat T-cells V Homo εapie 43
434677 AW444575 Hs 130834 ESTε 43
403310 43
451830 H18433 Hs 21542 KIAA1035 protein 43
422222 AI699372 Hs 193247 hypothetical protein DKFZp434A171 43
435627 W88774 Hs 118370 ESTs 43
436461 AW511956 Hs 293261 ESTs 43
452166 AI948607 Hs 264680 ESTs 43
413998 AW103807 Hs 243933 ESTs 42
416642 T96118 Hs 226313 ESTs 42
452081 AW958859 Hs 7514 Homo sapienε cDNA FLJ12141 fis, clone MA 42
452930 AW195285 Hs 194097 ESTs Weakly similar to I38022 hypotheti 42
407910 AA650274 Hs 41296 fibronectin leucine rich transmembrane p 4 2
428042 AA419529 Hs 76391 myxovirus (influenza) resistance 1, homo 42
424641 AB001106 Hs 151413 glia maturation factor, beta 42
417412 X16896 Hs 82112 interleukin 1 receptor, type I 42
409629 AW449589 Hs 279724 ESTs 4 2
458771 AW295151 Hs 163612 ESTs 42
415929 AA724373 Hs 49344 hypothetical protein FLJ11006 42
436645 AW023424 Hs 156520 ESTs 42
426083 AW962712 Hs 126712 ESTs, Weakly εimilar to AF191020 1 E2IG5 42
445268 AI218358 Hs 175048 ESTs 4 2
429629 BE501732 Hs 30622 Homo sapiens cDNA FLJ13010 fis, clone NT 42
431917 D16181 Hs 2868 peπpheral myelin protein 2 42
443348 AW873596 Hs 182278 calmodulin 2 (phosphorylase kinase, delt 42
443151 AI827193 Hs 132714 ESTs 42
419255 AA235672 Hs 87491 ESTs 42
452291 AF015592 Hs 28853 CDC7 (cell division cycle 7, S cerevisi 42
452561 AI692181 Hs 49169 KIAA1634 protein 4 2
421106 AA877124 Hs 172844 ESTs 42
424268 AA397653 Hs 307438 Human DNA sequence from clone 495010 on 42
425211 M18667 Hs 1867 progastncsin (pepεmogen C) 42
421515 Y11339 Hs 105352 GalNAc alpha-2, 6 εialyltransferase I, I 42
423045 AW967472 Hs 183302 PCTAIRE protein kinase 2 42
428771 AB028992 Hs 193143 KIAA1069 protein 41
445745 AB007924 Hs 13245 KIAA0455 gene product 4 1
417009 AA191719 Hs 314714 ESTs 4 1
436517 BE080932 Hs 135225 ESTs 4 1
425905 AB032959 Hs 318584 novel C3HC4 type Zinc finger (ring finge 41
414083 AL121282 Hs 257786 ESTs 4 1
452728 AI915676 Hs 239708 ESTs 4 1
409920 BE169746 Hs 12504 likely ortholog of mouse Arkadia 4 1
441802 AA968636 Hs 127877 ESTs 41
431956 AK002032 Hs 272245 Homo sapiens cDNA FLJ 11170 fis, clone PL 4 1
413875 BE176776 gb RC3-HT0586-110300 011-g09 HT0586 Homo 4 1
444009 AI380792 Hs 135104 ESTs 4 1
410785 AW803341 gb IL2-UM0079 090300-050-D03 UM0079 Homo 41
418882 NM 004996 Hs 89433 ATP-binding cassette, sub-family C (CFTR 4 1
438993 AA828995 gb od77b08 s1 NCI_CGAP_Ov2 Homo sapienε 4 1
435256 AF193766 Hs 13872 cytokine like protein C17 4 1
428104 AA421350 Hs 191604 ESTs 41
439648 AW780192 Hs 267596 ESTs 41
436194 AK001074 Hs 333435 Homo sapiens cDNA FU10212 fis, clone HE 4 1
446364 AB006624 Hs 14912 KIAA0286 protein 41
452744 AI267652 Hs 30504 Homo εapiens mRNA, cDNA DKFZp434E082 (fr 40
439294 AW975328 Hs 6523 chromoεome 1 open reading frame 12 40
408369 R38438 Hs 182575 solute earner family 15 (H+/peptιde tra 40
404561 40
401575 40
419296 AA236115 Hs 120785 ESTs 40
432055 AW972359 Hs 293334 ESTs 40
439107 AL046134 Hs 13944 adrenergic, beta, rxeptor kinase 2 40
450320 AW291775 Hs 213793 ESTs 40
447350 AI375572 Hs 172634 ESTs 40
441974 AI683782 Hs 128245 ESTs 40
453142 AA033648 Hs 7473 ESTs 40
409928 AL137163 Hs 57549 hypothetical protein dJ473B4 40
410292 AA843087 Hs 124194 ESTs 40
415811 AA450191 Hs 172963 hypothetical protein FLJ 14624 40
420218 AW958037 Hs 286 πbosomal protein L4 40
426625 T78300 Hε 300642 serologically defined colon cancer antig 40
417708 N74392 Hs 50495 ESTs 40
451024 AA442176 gb zw63b08 r1 Soares total_fetus Nb2HF8 40
411745 AW867826 gb MRO-SN0039 300300-001-c02 SN0039 Homo 40
422058 AA862231 Hs 334443 ESTs 40
439479 AI734258 Hs 245367 ESTs, Weakly similar to ALU1.HUMAN ALU S 40
409099 AK000725 Hs 50579 hypothetical protein FLJ20718 40
432222 AI204995 gb an03c03 x1 Stratagene schizo brain S1 40
444188 AI393165 Hs 699 peptidylpralyl iso erase B (cyclophilm 40
453096 AW294631 Hs 11325 ESTs 40
450297 AW901347 Hs 38592 hypothetical protein FLJ23342 40
421002 AF116030 Hs 100932 transcription factor 17 40
445414 AV653692 Hs 146105 ESTs 40 447207 AA442233 Hs 17731 hypothetical protein FLJ12892 40 451353 N21043 Hs 42932 ESTs 40
437075 AA743748 Hs 40758 ESTs 39
410505 AW752139 Hs 314323 ESTs 39
449746 AI668594 Hs 176588 ESTs, Weakly similar to CP4Y.HUMAN CYTOC 39 426116 AA868729 Hs 144694 ESTs 39
415716 N59294 Hs 179662 nucleosome assembly protein 1-lιke 1 39 436298 AW293496 Hs 180138 ESTs 39
417718 T86540 Hs 193981 ESTs 39
436772 AW975688 Hs 74170 metallolhionem 1E (functional) 39 401045 39
408767 AA057279 Hs 211928 ESTs 39
407303 AA016296 Hs 165200 ESTs, Weakly similar to A56194 thromboxa 39 432583 AW023624 Hs 162282 potassium channel TASK-4, potassium chaπ 39 451623 H77818 Hs 268991 ESTs 39
450063 AI681509 Hs 277133 ESTs 39
416734 H81213 Hs 14825 ESTs, Weakly similar to KIAA1503 protein 39 419276 BE165909 Hs 306881 MSTP043 protein 39 433132 AB026264 Hs 284245 hypothetical protein IMPACT 39 436149 AI754308 Hs 159452 ESTs 39
422667 H25642 Hs 133471 ESTs 39
443486 NM 003428 Hs 9450 zinc finger protein 84 (HPF2) 39 458219 H22195 Hs 31874 ESTs 39
443613 AI079356 gb oz39b09 s1 Soares NhHMPu S1 Homo sapi 39 439810 AL109710 Hs 85568 EST 39
436578 AI091435 Hs 134859 ESTs 39
415598 AI433165 Hs 9856 ESTs 39
425087 R62424 Hs 126059 ESTs 39
454111 AW081681 Hs 269064 ESTs, Weakly similar to T42689 hypotheti 39 409719 AI769160 Hs 108681 Homo sapiens brain tumor associated prot 39 452466 N84635 Hs 29664 hypothetical protein DKFZp564B052 39 424962 NM.012288 Hs 153954 TRAM like protein 39
435823 R07856 Hs 16355 ESTs 39
440633 AI140686 Hs 263320 ESTs 39
429334 D63078 Hs 186180 Homo sapiens cDNA FLJ23038 fis, clone L 39 444743 AA045648 Hs 301957 nudix (nucleoside diphosphate linked moi 39 430039 BE253012 Hs 153400 ESTs, Weakly similar to ALU1 HUMAN ALU S 39 417461 R38403 Hs 13305 ESTs 39
424051 AL110203 Hs 138411 Homo sapiens mRNA, cDNA DKFZp586J1922 (f 38 419140 AI982647 Hs 215725 ESTs 38
415652 T79213 Hs 272073 ESTs 38
430140 AW296771 Hs 221999 ESTs 38
446896 T15767 Hs 22452 Homo sapiens mRNA for KIAA1737 protein, 38 422165 AL041199 Hs 1481 histidine decarboxylase 38 417706 T90797 Hs 268623 ESTs 38
424296 AI631874 Hs 155140 casein kinase 2, alpha 1 polypeptide 38 450522 AI698839 gb wd31f02 x1 Soares_NFL_T_GBC_S1 Homo s 38 446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontin, 38 449729 R72032 Hs 29235 ESTε 38
414700 H63202 Hs 38163 ESTs 38
440899 AW449445 Hs 120021 DKFZP434I092 protem 38 439335 AA742697 Hs 62492 ESTs, Weakly similar to B39066 prolme-r 38 408625 AW243323 Hs 266785 ESTs 38
421987 AI133161 Hε 286131 CGI-101 protein 38 418915 AI474778 Hs 118977 ESTs 38
410224 M55513 Hs 150208 potassium voltage-gated channel, shaker- 38 429846 AB023021 Hs 225945 fucosyltransferase 9 (alpha (1,3) fucosy 38 442849 R10099 Hε 269805 ESTs 38
427191 BE221825 Hs 97691 ESTs 38
407942 AA378608 Hs 5894 hypothetical protein FLJ10305 38 437030 AA742577 Hs 303781 EST 38
427940 AA417812 Hs 38775 ESTs 37
443054 AI745185 Hs 8939 yes assxiated protein 65 kDa 37 449679 AI823951 Hs 129700 tolloid-hke 1 37
425937 NM 013240 Hs 163846 putative N6-DNA-methyltransferase 37 458663 AV658444 Hs 280776 tankyrase, TRF1-ιnterxtιng ankyπn rela 37 456443 AW967500 Hs 133543 ESTs 37
439957 AI453184 Hs 66357 ESTs 37
446999 AA151520 Hs 334822 hypothetical protein MGC4485 37 428414 AL049980 Hs 184216 DKFZP564C152 protein 37 455170 AW860972 gb QVO-CT0387-180300-167-h07 CT0387 Homo 37 418379 AA218940 Hs 137516 fidgetin like 1 37
419720 AA249131 Hs 337778 hypothetical protein FLJ11068 37 443584 AI807036 Hs 267245 hypothetical protein FLJ 14803 37 416185 AW975861 Hs 47367 KIAA1785 protein 37 417235 AA810278 Hs 24250 ESTs 37
441720 AI346487 Hs 28739 ESTs 37
451421 W16522 Hs 237689 Homo sapiens cDNA FLJ13539 fis, clone PL 37 417355 D13168 Hs 82002 endothelin rxeptor type B 37 449321 AA001150 Hs 132937 ESTs 37
424806 AA382523 Hs 105689 MSTP031 protein 37 452338 AW608920 Hs 29159 zinc finger protein 75 (D8C6) 37 409248 AB033035 Hs 51965 KIAA1209 protein 37 421037 A1684808 Hs 197653 ESTs 37
427088 AA398085 Hs 142390 ESTs 37
420637 AW976153 gb EST388262 MAGE resequences, MAGN Homo 37
420026 AI831190 Hs 166676 ESTs 37
429419 AB023226 Hs 202276 KIAA1009 protein 37
447410 AI470235 Hs 172698 EST 37
404274 37
416320 H47867 Hs 34024 ESTs 37
412642 BE244598 Hs 809 hepatocyte growth factor (hepapoietm A, 37
431716 D89053 Hs 268012 fatty-xid Coenzyme A ligase, long chain 37
446025 AW305075 Hs 180948 KIAA0729 protein 37
450458 AA009926 gb zι07e05 r1 Soares.fetal.liver.spleen. 37
423099 NM 002837 Hs 123641 protein tyrosine phosphatase receptor t 36
438257 AW474419 Hs 224794 ESTs 36
440887 AI799488 Hs 135905 ESTs 36
454693 AW813428 gb MR3 ST0192-010200-210-C05 ST0192 Homo 36
432189 AA527941 gb nh30c04 s1 NCI_CGAP_Pr3 Homo sapiens 36
408687 AL110280 Hs 301152 Homo sapiens mRNA, cDNA DKFZp434F053 (fr 36
407726 AA435679 Hs 88594 ESTs 36
436026 AI349764 Hs 217081 ESTs 36
448776 BE302464 Hs 30057 MRS2 (S cerevisiae) like, magnesium hom 36
452293 AI871833 Hs 304609 ESTs 36
428330 L22524 Hs 2256 matnx metalloproteinase 7 (matπlysin, 36
443268 AI800271 Hs 129445 hypothetical protein FU12496 36
429208 AA447990 Hs 190478 ESTs 36
458429 AV646559 Hs 12346 Homo sapiens cDNA FLJ21399 fis, clone C 36
404476 36
405848 36
438209 AL120659 Hs 6111 aryl hydrocarbon receptor nuclear transi 36
403937 36
437918 AI761449 Hε 121629 ESTs 36
432408 N39127 Hs 332557 ESTs, Weakly similar to A46010 X linked 36
437641 AA811452 Hs 291911 ESTs 36
439635 AA477288 Hs 94891 hypothetical protein FLJ22729 36
446102 AW168067 Hs 252956 ESTs 36
418384 AW149266 Hs 25130 Homo sapiens cDNA FLJ14923 fis, clone PL 36
425403 AL023753 Hs 156406 Human DNA sequence from clone 1198H6 on 36
432030 AI908400 Hs 143789 ESTs 36
446453 AV658469 Hs 188646 ESTs, Weakly similar to ALULHUMAN ALU S 36
452055 A1377431 Hs 141693 hypothetical protein MGC10858 36
440801 AA906366 Hs 190535 ESTs 36
432779 AW979241 gb EST391351 MAGE resequences, MAGP Homo 36
440886 AW511032 Hs 190516 ESTs 36
401049 36
449424 AW448937 Hs 197030 ESTs 36
418076 R61388 Hs 6724 ESTs 36
423035 AW449679 Hs 156739 H sapiens XG mRNA (clone PEP11) 36
435463 AA682507 gb zj18f08s1 Soares fetal liver εpleen 36
438016 A1949638 Hs 336846 EST 36
455201 AW947884 gb PM1-MT0010-200300 001-g08 MT0010 Homo 36
433293 AF007835 Hs 32417 hypothetical protein MGC4309 35
456536 AW135986 Hs 257859 ESTs 35
428679 AA431765 gb zw80c03 s1 Soares estis.NHT Homo sap 35
414400 X06948 Hs 897 Fc fragment of IgE, high affinity I, rx 35
435344 AA700326 Hs 190599 ESTs 35
445056 AB014530 Hs 12259 KIAA0630 protein 35
449444 AW818436 Hs 23590 solute earner family 16 (monxarboxylic 35
442652 AI005163 Hs 201378 ESTs, Weakly similar to T12545 hypotheti 35
423121 AW864848 gb PM2-SN0018-290300-003x09 SN0018 Homo 35
449540 AA001713 gb zh86eQ8 s1 Soares_fetal_lιver_spleen_ 35
425734 AF056209 Hε 159396 peptidylglycme alpha amidat g moπooxyg 35
428409 AW117207 Hs 98523 ESTs 35
431087 H12723 Hs 290791 ESTs 35
426920 AA393351 Hs 132121 ESTs 35
427687 AW003867 Hs 1570 histamine rxeptor H1 35
437583 AA761190 Hs 244627 ESTs 35
421599 AA293655 Hs 97293 ESTs 35
433687 AA743991 gb ny57g01 s1 NCI CGAP_Pr18 Homo sapiens 35
421863 AI952677 Hs 108972 Homo sapiens mRNA, cDNA DKFZp434P228 (fr 35
430499 AW969408 Hs 231991 ESTs 35
451531 AA018311 Hs 114762 ESTε 35
457620 AA602711 Hs 336753 EST 35
410658 AW105231 Hs 192035 ESTε 35
427865 AA416931 Hs 126065 ESTs 35
453390 AA862496 Hs 28482 ESTs 35
419983 W55956 Hs 94030 Homo sapiens mRNA, cDNA DKFZp586E1624 (f 35
454600 AW810001 gb MR4-ST0124-270300005 b11 ST0124 Homo 35
427718 AI798680 Hs 25933 ESTs 35
416548 H62953 gb yr47f06 r1 Soares fetal liver spleen 35
420381 D50640 Hs 337616 phosphodiesterase 3B, cGMP-mhibited 35
410908 AA121686 Hs 10592 ESTs 35
442080 AW444761 Hs 44565 ESTs 35
406685 M18728 gb Human nonspecific crossreacting antig 35 404200 35
417976 BE565892 Hs 83077 interleukin 18 (interferon-gamma inducm 35
433285 AW975944 Hs 237396 ESTs 35
432868 AW974093 Hs 292775 ESTs 35
433492 AW605849 gb MRO HT0241-200100 006-g02 HT0241 Homo 35
410252 AW821182 Hs 61418 microfibnllar-associated protein 1 34
428804 AK000713 Hs 193736 hypothetical protein FLJ20706 34
428775 AA434579 Hs 143691 ESTs 34
410004 AI298027 Hs 5057 carboxypeptidase D 34
422093 AF151852 Hs 111449 CGI-94 protein 34
441736 AW292779 Hs 169799 ESTs 34
423017 AW178761 Hs 227948 serine (or cysteine) proteinase inhibito 34
405970 34
431954 AK001974 Hs 272242 hypothetical protein FU11112 34
459482 AA625339 Hs 237052 EST, Weakly similar to I38022 hypothetic 34
410361 BE391804 Hs 62661 guanylate binding protein 1, mterferon- 34
410804 U64820 Hs 66521 Mxhado-Joseph disease (spmxerebellar 34
402230 34
436120 AI248193 Hs 119860 ESTε 34
405336 34
434374 AA631439 gb np85d02 s1 NCI CGAP Thy1 Homo sapiens 34
428911 Z43846 Hε 194478 Homo sapiens mRNA, cDNA DKFZp43401572 (f 34
437783 AI683150 Hs 201550 ESTs, Weakly similar to ALU1 HUMAN ALU S 34
416057 AI927382 Hs 29857 ESTε 34
435496 AW840171 Hs 265398 ESTε, Weakly similar to transformation-r 34
436088 AA704687 Hs 191294 ESTε 34
408554 AA836381 Hs 315111 nuclear rxeptor co repressor/HDAC3 comp 34
454076 AW204712 Hs 61957 ESTs 34
431733 AW298410 Hs 21475 ESTs 34
432974 BE348793 Hs 233331 ESTs 34
412576 AA447718 Hs 107057 ESTs 34
446142 A1754693 Hs 145968 ESTε 34
447432 AW958473 Hs 301957 nudix (nucleoεide diphosphate linked moi 34
433384 AI021992 Hs 124244 ESTs 34
413621 AI808648 Hs 184156 ESTs 34
419546 AA244199 gb nc06c05 s1 NCI CGAP Pr1 Homo sapiens 34
436111 AI803082 Hs 157212 ESTs 34
421236 AI287622 Hs 151956 ESTs 34
433917 AI809325 Hs 122814 Human DNA sequence from clone RP5-1028D1 34
403515 34
429657 D13626 Hs 2465 KIAA0001 gene product putative G-protei 34
453375 AI990114 Hs 240091 ESTs 34
448186 AA262105 Hs 4094 Homo sapiens cDNA FLJ14208 fis, clone NT 34
412209 AW901456 gb RCO-NN1012-270300 031-C07 NN1012 Homo 34
421065 AA329711 gb EST33382 Embryo, 12 week II Homo sapi 34
409642 AW450809 Hs 257347 ESTs 34
420092 AA814043 Hs 88045 ESTs 34
453365 AA035211 Hs 17404 ESTs 33
437007 AA741300 Hs 202599 ESTs, Weakly similar to I38022 hypotheti 33
408031 AA081395 Hs 42173 Homo sapiens cDNA FLJ 10366 fis, clone NT 33
439024 R96696 Hs 35598 ESTs 33
418432 M14156 Hs 85112 insulin-like growth factor 1 (εomatomedi 33
417991 AA731452 Hs 190008 ESTε 33
403356 33
433650 AA603472 Hs 28456 ESTs 33
410318 AA084050 Hs 269259 ESTs, Weakly similar to S23650 retroviru 33
427019 AA001732 Hs 173233 hypothetical protein FLJ 10970 33
413714 AI560944 Hs 71428 ESTs 33
430887 N66801 Hs 260287 KIAA1841 protein 33
413618 BE154078 gb PM0-HT0339-200400 010-F04 HT0339 Homo 33
420908 AL049974 Hs 100261 Homo sapiens mRNA, cDNA DKFZp564B222 (fr 33
436168 AK000883 Hs 301645 Homo sapiens cDNA FLJ10021 fis, clone HE 33
405692 33
432809 AA565509 Hs 131703 ESTs 33
433805 AA706910 Hs 112742 ESTs 33
436192 W93847 Hs 24139 Homo sapienε cDNA FLJ23137 fis, clone L 33
435451 AF195420 Hs 303006 ESTs, Weakly similar to gamma-heregulin 33
411849 AW964970 Hs 18861 ESTs, Moderately similar to KIAA1276 pro 33
448404 BE089973 gb RC6-BT0709-310300-021-G07 BT0709 Homo 33
410434 AF051152 Hs 63668 toll like rxeptor 2 33
416421 AA134006 Hs 79306 eukaryotic translation initiation fxtor 33
438394 BE379623 Hs 27693 peptidylprolyl isomerase (cyclophιlιn)-l 33
444301 AK000136 Hs 10760 aspoπn (LRR class 1) 33
428795 R45503 Hs 97469 ESTs, Highly similar to A39769 N xetyll 33
458924 BE242158 Hs 24427 DKFZP56601646 protein 33
435934 R19382 Hs 117869 ESTs 33
400269 33
410555 U92649 Hs 64311 a disintegnn and metalloproteinase doma 33
412903 BE007967 Hs 155795 ESTs 33
400889 33
449585 AI655321 Hs 197693 ESTs 33
408806 AW847814 Hs 289005 Homo sapiens cDNA FLJ21532 fis, clone C 33
418557 BE140602 Hs 246645 ESTs 33 453204 R10799 Hs 191990 ESTs 33
450696 AI654223 Hs 16026 hypothetical protein FLJ23191 33
427374 AI150033 Hs 143686 ESTs 33
443367 AW071349 Hs 215937 ESTs 33
446645 AI336596 Hs 156294 ESTs 33
449897 AW819642 Hs 24135 transmembrane protein vezatin, hypotheti 33
428467 AK002121 Hs 184465 hypothetical protein FLJ11259 33
408761 AA057264 Hs 238936 ESTs Weakly similar to (defline not ava 33
403895 32
414899 AW975433 Hs 36288 ESTs 32
409044 AI129586 Hs 33033 hypothetical protein FLJ14623 32
447233 AW246333 Hs 17901 Homo sapiens, clone IMAGE 3937015, mRNA 32
422219 AW978073 Hs 1010 regulator of mitotic spindle assembly 1 32
427119 AW880562 Hs 114574 ESTs 32
437073 AI885608 Hs 94122 ESTs 32
443830 AI142095 Hs 143273 ESTs 32
454962 AW847645 gb IL3-CT0213 280100 056-A04 CT0213 Homo 32
433644 AW342028 gb hb75d03 x1 NCI_CGAP_UI2 Homo sapiens 32
417561 AW974345 gb EST386449 MAGE resequences, MAGM Homo 32
446063 AI720140 Hs 151079 ESTs 32
423609 AA328348 Hs 218289 ESTs 32
428004 AA449563 Hs 151393 glutamate cysteine ligase, catalytic sub 32
453370 AI470523 Hs 139336 ATP-binding cassette sub family C (CFTR 32
435808 AA702866 Hs 113150 ESTs 32
424001 W67883 Hs 137476 paternally expressed 10 32
415635 F13168 gb HSC3JF101 normalized infant brain cDN 32
418946 AI798841 Hs 164526 ESTs 32
431750 AA514986 Hs 283705 ESTs 32
425188 AK002052 Hs 155071 hypothetical protein FLJ11190 32
428268 AA424957 Hs 294132 ESTε 32
418878 W20090 Hs 6616 ESTε 32
416565 AW000960 Hs 44970 endoplasmic reticulum resident protein 5 32
454288 BE222648 Hs 279458 ESTs, Highly similar to c380A1 1b [H sap 32
446428 AW082270 Hε 12496 ESTs Weakly similar to ALU4.HUMAN ALU S 32
404588 32
413087 BE064655 gb RC1-BT0313-301299 012-C09 BT0313 Homo 32
444910 AI201849 gb qs76g04 x1 NCLCGAP Pr28 Homo sapiens 32
407339 AA777542 Hε 132670 ESTs 32
414093 BE544867 Hs 283077 centrosomal P41-aεεocιated protein, unc 32
438458 AW975186 gb EST387294 MAGE reεequences, MAGN Homo 32
419340 AA236590 Hs 87530 ESTs 32
423448 AK000776 Hs 128753 Homo sapiens cDNA FLJ20769 fis clone CO 32
457030 AI301740 Hs 173381 dihydropynmidinase like 2 32
421187 NM.014721 Hs 102471 KIAA0680 gene product 32
419829 U90268 Hs 93810 cerebral cavernous malformations 1 32
429276 AF056085 Hs 198612 G protein-coupled rxeptor 51 32
423841 AW753967 gb RC2-CT0304-080100 011-h12 CT0304 Homo 32
438839 AW297945 Hs 128490 ESTs 32
410085 AA428482 Hs 58589 glycogenm 2 32
427961 AW293165 Hε 143134 ESTs 32
429228 AI553633 Hs 337139 ESTs 32
431548 AI834273 Hs 9711 novel protein 31
441839 AW975512 Hs 29160 ESTs 3 1
410389 AW954049 Hs 8177 ESTs, Weakly similar to PIHUB6 salivary 3 1
441274 AW593781 Hs 131357 ESTs 3 1
452401 NM 007115 Hs 29352 tumor nxroεiε factor, alpha induced pro 3 1
436154 AA764950 Hs 119898 ESTs 3 1
406752 AI285598 gb qu49f06 x1 NCI_CGAP_Lym6 Homo sapiens 3 1
450689 AI369275 Hs 243010 Homo sapiens cDNA FU14445 fis, clone HE 3 1
434164 AW207019 Hs 148135 seππe/threonme kinase 33 3 1
436739 BE208022 Hs 127685 KIAA1627 protein 3 1
451674 AA019104 Hs 175483 Homo sapiens cDNA FU22016 fis, clone H 3 1
421166 AA305407 Hs 102308 potassium inwardly rectifying channel, s 3 1
437872 AK002015 Hs 5887 RNA binding motif protein 7 3 1
440046 AW402306 Hs 6877 hypothetical protein FU 10483 3 1
452824 W27643 Hs 73965 splicing fxtor, arginine/seπne-πch 2 3 1
426457 AW894667 Hs 169965 chimeπn (chimaenn) 1 3 1
424780 U39576 Hs 153058 butyrophiliπ, subfamily 1, member A1 3 1
456551 AW975051 Hs 293156 ESTs, Weakly similar to I78885 seπne/th 3 1
410763 AF279145 Hs 8966 hypothetical protein FLJ21776 3 1
431814 BE256242 Hs 270847 delta tubulm 3 1
440099 AL080058 Hs 6909 DKFZP564G202 protein 3 1
436401 AI087958 Hs 29088 ESTs 3 1
437439 H29796 Hs 269622 ESTs 3 1
403277 3 1
408547 AA574291 Hs 57837 ESTs 3 1
424131 AA335714 Hs 199665 ESTs 3 1
433222 AW514472 Hs 238415 ESTs, Moderately similar to ALU8_HUMAN A 3 1
434636 AA083764 Hs 6101 hypothetical protein MGC3178 3 1
450519 AA010066 Hs 224849 i Homo sapiens cDNA FLJ12583 fis, one NT 3 1
415083 AI632683 Hs 27179 Homo sapiens cDNA FLJ12933 fis, clone NT 3 1
407905 AW103655 Hs 25290E i ESTs 3 1
452311 AW304029 Hs 252744 \ ESTs 3 1 434849 AW292765 Hs 8053 ESTs 31
446770 AV660309 Hs 154986 ESTε, Weakly similar to PLLP.HUMAN PLASM 31
424238 AA337401 Hs 137635 ESTs 31
411643 AI924519 Hs 192570 hypothetical protein FLJ22028 31
447829 AI433029 Hs 164104 ESTs 31
406506 31
428301 AW628666 Hs 98440 ESTs, Weakly similar to 138022 hypotheti 31
428579 NM 005756 Hs 184942 G protein coupled receptor 64 31
451228 AW967707 Hs 48473 ESTs 31
401103 31
433589 AA886530 Hs 188912 ESTs 31
459370 AA889982 Hs 271826 ESTs, Weakly similar to I38022 hypotheti 31
438533 AI440266 Hs 170673 ESTs, Weakly similar to T24832 hypotheti 31
404288 31
406195 31
438202 AW169287 Hs 22588 ESTs 31
425516 BE000707 Hs 29567 ESTs 31
426572 AB037783 Hs 170623 hypothetical protein FLJ11183 31
422692 AA332376 Hs 24135 transmembrane protein vezat , hypotheti 31
435414 AW270550 Hs 116957 ESTs 31
418950 T78517 Hs 13941 ESTs 31
426890 AA393167 Hs 41294 ESTs 31
457447 X78261 Hs 272177 H sapiens mRNA for TRE175' extremity an 31
443773 AV646452 Hs 30941 calcium channel, voltage-dependent, beta 31
459371 R20991 gb yg06h01 r1 Soares infant brain 1 IB H 31
421823 N40850 Hs 28625 ESTs 31
447247 AW369351 Hs 287955 Homo sapiens cDNA FLJ13090 fis, clone NT 31
452896 AA831508 Hs 32553 ESTs 31
425895 AI269484 Hs 161427 zinc finger protein 215 31
451403 AA885569 Hs 40919 Homo sapiens cDNA FLJ 14511 fis, clone NT 31
407340 AA810168 Hs 284289 vitiligo associated protein VIT-1 31
401862 31
444325 AW152618 Hs 16757 ESTs 31
408171 AA301228 Hs 43299 hypothetical protein FLJ 12890 31
423949 AI014546 Hs 130912 ESTs 31
419519 AI198719 Hs 176376 ESTs 30
434683 AW298724 Hε 202639 ESTs 30
418454 AA315308 Hs 195870 hypothetical protein FLJ 14991 30
415086 AI597963 Hs 118726 ESTs 30
419220 AA811938 Hs 291759 ESTs 30
418849 AW474547 Hs 53565 Homo sapiens PIG-M mRNA for mannosyltran 30
443634 H73972 Hs 134460 ESTs 30
429682 NM.006306 Hs 211602 SMC1 (structural maintenance of chromoso 30
405090 30
432267 AK000872 Hs 274227 Homo sapiens cDNA FLJ10010 fis, clone HE 30
443253 AI041212 Hs 132117 ESTs 30
444974 AI203500 Hs 151612 ESTs 30
445717 AW664658 Hs 149332 ESTs 30
449347 AV649748 Hs 295901 KIAA0493 protein 30
452778 R71338 Hs 5921 Homo sapiens cDNA FLJ21592 fis, clone C 30
414888 AL039185 Hs 77558 thyroid hormone rxeptor interxtor 7 30
424406 D54120 Hs 146409 cell division cycle 42 (GTP-bindmg prot 30
410371 AA084482 Hs 115850 ESTs 30
426384 AI472078 Hε 303662 ESTs 30
418200 AW629751 Hs 206654 ESTs, Weakly similar to alternatively sp 30
427050 AA397789 Hε 161803 ESTε 30
449579 AW207260 Hs 134014 ESTs, Weakly similar to T46425 hypotheti 30
411004 AW813242 gb MR3-ST0191-020200-207-g10 ST0191 Homo 30
454032 W31790 Hε 194293 ESTs, Weakly similar to 154374 gene NF2 30
455601 AI368680 Hs 816 SRY (sex determining region Y)-box 2 30
447482 AB033059 Hs 18705 KIAA1233 protein 30
439416 W58294 Hs 56254 ESTs 30
436635 AW104325 Hs 272093 ESTs, Weakly similar to I78885 seππe/th 30
419086 NMJ00216 Hε 89591 Kallmann εyndrame 1 εequence 30
412566 AW962574 gb EST374647 MAGE resequences MAGG Homo 30
415452 F09134 Hs 12839 ESTs 30
427874 AA732367 Hs 98198 ESTs 30
447046 AA326187 Hs 17170 G protein-coupled rxeptor 4 30
454193 BE141183 gb MRO-HT0071-191199-001-b04 HT0071 Homo 30
454678 AW813089 gb RC3-ST0186-240400-111-b05 ST0186 Homo 30
415122 D60708 Hs 22245 ESTs 30
444665 BE613126 Hs 47783 B aggressive lymphoma gene 30
400227 30
411905 BE265067 gb 601193893F1 NIH MGC_7 Homo sapiens cD 30
419503 AA243642 Hs 137422 ESTs 30
446563 BE326588 Hs 141454 ESTs 30
457285 AI038858 Hs 130522 Kv channel interacting protein 1 30
434998 AW975157 Hs 26037 ESTs 30
436203 BE384982 Hs 5076 Homo sapiens cDNA FLJ22128 fis, clone H 30
424539 L02911 Hs 150402 xtivm A rxeptor, type I 30
449856 AA203155 Hs 18200 ESTs 30
427698 AW972594 Hs 294140 ESTs 30
451494 AI799444 Hs 247095 ESTs, Moderately similar to ALU7.HUMAN A 30 442994 AI026718 Hs 16954 ESTs 30
408165 AL137573 Hs 43143 Homo sapiens mRNA, cDNA DKFZp564A2463 (f 30
421072 AI215069 Hs 89113 ESTs 30
456273 AF154846 Hs 1148 zinc finger protein 30
404548 30
428201 AA424158 Hs 206461 ESTs 30
441519 AA972740 Hs 127092 ESTε 30
445413 AA151342 Hs 12677 CGI-147 protein 30
418717 AI334430 Hs 86984 ESTs 30
428839 AI767756 Hs 82302 Homo sapiens cDNA FLJ14814 fis clone NT 30
407758 D50915 Hs 38365 KIAA0125 gene product 30
431906 AW328038 Hs 37486 ESTε 30
424968 AA349086 Hs 259746 ESTs Weakly similar to A46010 X linked 30
431023 A1283133 Hs 297420 ESTs 30
432596 AJ224741 Hs 278461 matπlin 3 30
452412 AA029608 Hs 61373 ESTs 30
421309 A1222086 Hs 270449 ESTs, Moderately similar to ALULHUMAN A 29
438128 AA904430 Hs 122049 ESTs, Weakly similar to T2D4.HUMAN TRANS 29
408321 AW405882 Hs 44205 cortistatin 29
439236 BE160952 Hs 247117 ESTs, Moderately similar to ALUF_HUMAN ι 29
400880 29
417014 AA251720 Hs 104347 ESTs, Weakly similar to ALUC_HUMAN "« 29
422278 AF072873 Hs 114218 frizzled (Drosophila) homolog 6 29
406603 29
425573 AB006423 Hs 158308 senne (or cysteine) proteinase inhibito 29
427878 C05766 Hs 181022 CGI 07 protein 29
451700 AI470262 Hs 29553 ESTε 29
451797 AW663858 Hs 333513 small inducible cytokine subfamily E, me 29
423025 AA831267 Hs 12244 hypothetical protein FLJ 20097 29
422634 NM 016010 Hs 118821 CGI 62 protein 29
448966 AW372914 Hs 86149 phospho ositol 3-phosphate-bιndιπg prot 29
408690 AW864542 gb PM4-SN0016-120500 003-h02 SN0016 Homo 29
408525 AW206972 Hs 253595 ESTε 29
412248 BE176480 gb RC3 HT0585-160300022 c02 HT0585 Homo 29
432507 BE391093 Hs 324667 ESTs 29
447290 AI476732 Hs 263912 ESTs 29
424188 AW954552 Hs 142634 zinc finger protein 29
431448 AL137517 Hs 334473 hypothetical protein DKFZp56401278 29
400325 M85292 Hs 247924 Homo sapiens endogenous HIV-1 related se 29
408408 AF070571 Hs 44690 Homo sapiens clone 24739 mRNA sequence 29
423119 AA322201 Hs 131976 ESTs 29
423717 AA330036 Hs 152003 ESTs 29
424152 AL133591 Hs 141480 Homo sapiens mRNA, cDNA DKFZp434N079 (fr 29
431980 AA523696 Hs 324507 hypothetical protein FLJ20986 29
434980 AW770553 Hs 14553 sterol O acyltransferase (xyl Coenzyme 29
444339 T96555 Hs 31562 ESTs 29
446745 AW118189 Hs 156400 ESTs 29
459201 AW391177 gb MR3 ST0203-221299-023-d05 ST0203 Homo 29
430573 AA744550 Hs 136345 ESTs 29
451073 A1758905 Hs 206063 ESTs 29
440575 AA889870 Hs 126006 ESTs 29
402046 29
426882 AA393108 Hs 97365 ESTs 29
435738 AA699633 Hs 269543 ESTs, Weakly similar to A56194 thromboxa 29
420656 AA279098 Hs 187636 ESTs 29
438323 AI985394 Hs 123369 ESTs 29
453123 AI953718 Hs 221849 ESTs 29
418343 AA216372 Hs 159501 ESTs 29
431595 AA508196 gb nh60f07 s1 NCI_CGAP_Pr8 Homo εapienε 29
436187 AK000998 Hs 297221 Homo εapienε cDNA FLJ10136 fis, clone HE 29
459440 BE048054 gb tz46c03y1 NCI_CGAP_Brn52 Homo sapieπ 29
451957 AI796320 Hs 10299 Homo sapiens cDNA FLJ13545 fis, clone PL 29
408434 AW195317 Hs 107716 hypothetical protein FLJ22344 29
456034 AW450979 gb UI H BI3-ala-a-120-UI s1 NCI CGAP.Su 29
442118 AA976718 Hs 202242 ESTε 29
420727 H75701 Hs 99886 complement component 4-bιndιng protein, 29
433849 BE465884 Hs 280728 ESTs 29
424235 NM 003181 Hs 143507 T brachyury (mouse) homolog 29
429826 N93266 Hs 40747 ESTs 29
437913 AI140825 Hs 121623 ESTs 29
441330 AI692984 Hs 129354 ESTs 29
443458 R05385 Hs 143509 hypothetical protein FLJ21924 29
438873 A1302471 Hs 124292 Homo sapiens cDNA FLJ23123 fis, clone L 29
444561 NM 004469 Hs 11392 c fos induced growth factor (vascular en 29
444631 AW995395 Hs 84520 ESTs, Weakly similar to TRHY HUMAN TRICH 29
458186 AA904244 Hs 153205 ESTs 29
436043 AW963838 Hs 168830 Homo sapiens cDNA FLJ12136 fis, clone MA 29
415757 AA830854 Hs 187810 ESTs 29
449299 AA299919 Hs 84561 ESTs 29
457003 S78234 Hs 172405 cell division cycle 27 29
408875 NM 015434 Hs 48604 DKFZP434B168 protein 29
424602 AK002055 Hs 151046 hypothetical protein FLJ11193 29
426174 AA547959 Hs 115838 ESTs 29 449318 AW236021 Hs 78531 Homo sapiens, Similar to RIKEN cDNA 5730 29
429950 AW081608 Hs 105053 ESTs 29
412733 AA984472 Hs 74554 KIAA0080 protein 29
423637 AL137279 Hs 130187 Homo sapiens mRNA, cDNA DKFZp43401214 (f 29
442655 AW027457 Hs 30323 ESTs, Weakly similar to B34087 hypotheti 29
420556 AA278300 Hs 124292 Homo sapienε cDNA FLJ23123 fis, clone L 29
430447 W17064 Hs 332848 SWI/SNF related matnx associated acti 29
416871 H98716 gb yx13d08 s1 Soares melanocyte 2NbHM Ho 29
439737 AI751438 Hs 41271 Homo sapiens mRNA full length insert cDN 29
406815 AA833930 Hs 288036 tRNA isopentenylpyrophosphate transferas 29
401094 29
401526 29
414140 AA281279 Hs 23317 hypothetical protein FLJ14681 29
417320 AA195667 Hs 86022 ESTs 29
418282 AA215535 Hs 98133 ESTs 29
442927 AI024347 Hs 131519 ESTε 29
450006 AI241555 Hs 60171 ESTε 29
419231 AL046294 Hs 136245 ESTs, Weakly similar to T17227 hypotheti 28
416623 N74925 Hs 38761 Homo sapiens cDNA FLJ21564 fis, clone C 28
403329 28
414696 AF002020 Hs 76918 Niemanπ Pick disease, type C1 28
419038 AW134924 Hs 190325 ESTs 28
440106 AA864968 Hs 127699 KIAA1603 protein 28
448019 AW947164 Hs 195641 ESTs, Moderately similar to I38022 hypot 28
431745 AW972448 Hs 163425 ESTs 28
421426 AA291101 Hs 33020 Homo sapiens, clone IMAGE 3939163, mRNA, 28
433014 NM 014711 Hs 279912 KIAA0419 gene product 28
455100 BE160198 gb QV1-HT0413-010200 059 h03 HT0413 Homo 28
441790 AW294909 Hs 132208 ESTs 28
404443 28
428129 AI244311 Hs 26912 ESTs 28
435047 AA454985 Hs 54973 cadheπn-like protein VR20 28
423948 AW392342 Hs 283077 centrosomal P4 1-assocιated protein, unc 28
449327 AI638743 Hs 224672 ESTs 28
400983 28
415786 AW419196 Hs 257924 hypothetical protein FLJ13782 28
411213 AA676939 Hs 69285 neuropilin 1 28
420896 AW149342 Hs 24444 Homo sapienε cDNA FLJ22165 fis, clone H 28
409994 D86864 Hs 57735 acetyl LDL receptor, SREC 28
430388 AA356923 Hs 240770 nuclear cap binding protein subunit 2, 2 28
419530 X98330 Hs 90821 ryanodme receptor 2 (cardiac) 28
455092 BE152428 gb CM0 HT0323 151299-126-b04 HT0323 Homo 28
456118 AA380267 Hs 78277 DKFZP434F2021 protein 28
440192 AA872282 Hs 190596 ESTs 28
448466 AI522109 Hs 171066 ESTs 28
414869 AA157291 Hs 21479 ubinucle 1 28
440351 AF030933 Hs 7179 RAD1 (S pombe) homolog 28
407594 AW057584 Hs 160681 ESTs 28
439235 N45513 Hs 46608 ESTs 28
417061 AI675944 Hs 188691 Homo sapiens cDNA FLJ 12033 fis, clone HE 28
434812 AA649860 Hs 189496 ESTs 28
409731 AA125985 Hs 56145 thymosm, beta, identified in neuroblast 28
455512 AW983608 gb RC3 HN0001-240400-012-C01 HN0001 Homo 28
408380 AF123050 Hs 44532 diubiquit 28
435990 AI015862 Hs 131793 ESTs 28
410672 AW794600 gb RC6-UM0014-170300-022-C05 UM0014 Homo 28
432798 AA565309 Hs 194015 ESTs 28
416288 H51299 gb yp07c06 s1 Soares breast 3NbHBst Homo 28
438886 AA827728 Hs 128705 ESTs, Weakly similar to AF149422 2 unkno 28
451558 NM 001089 Hs 26630 ATP-bmding cassette, sub-family A (ABC1 28
416940 N75620 Hs 43157 ESTs 28
421750 AK000768 Hs 107872 hypothetical protein FLJ20761 28
438398 AA806526 Hs 130277 ESTs 28
435313 AI769400 Hs 189729 ESTs 28
414605 BE390440 gb 601283601F1 NIH_MGC_44 Homo sapiens c 28
436508 AW604381 Hs 121121 ESTs, Weakly similar to S00755 plxkstπ 28
413195 AA127382 Hs 22404 protease, seπne, 12 (neurotrypsm, moto 28
413829 NM 01872 Hs 75572 carboxypeptidase B2 (plasma) 28
401323 28
408296 AL117452 Hs 44155 DKFZP586G1517 protein 28
428532 AF157326 Hε 184786 TBP-mteracting protein 28
423454 AL110456 Hs 469 succinate dehydrogenase complex, subunit 28
436027 A1864053 Hs 39972 ESTs, Weakly similar to 138588 reverse t 28
406970 M29994 gb Human alpha 1 spectπn gene, exon 12 28
426172 AA371307 Hs 125056 ESTε 28
452114 N22687 Hs 8236 ESTs 28
439750 AL359053 Hs 57664 Homo sapienε mRNA full length insert cDN 28
423130 AW897586 Hs 21213 ESTs 28
430660 R11884 Hs 100826 ESTs 28
434138 AA625804 gb zu86h01 s1 Soares.testis.NHT Homo sap 28
427469 AA403084 Hs 269347 ESTs, Weakly similar to 2109260A B cell 28
429881 T80112 Hs 192245 ESTs 28
411492 T46848 Hs 70337 immunoglobulin superfamily, member 4 28 409435 AI810721 Hs 95424 ESTs 28
442191 W95186 Hs 8136 endothelial PAS domain protein 1 28
407305 AA715284 gb nv35f03 r1 NCI.CGAP.Brδ Homo sapiens 28
444381 BE387335 Hs 283713 ESTs, Weakly similar to S64054 hypotheti 28
412189 R60982 Hs 22581 ESTs 28
420976 AI924940 Hs 108082 ESTs, Weakly similar to T31636 hypotheti 28
448330 AL036449 Hs 207163 ESTs 28
418912 NM 000685 Hs 89472 angiotensm receptor 1 28
422505 AL120862 Hs 124165 ESTε 28
427752 AA470687 Hs 104772 ESTε 28
433513 AI566356 Hs 171437 ESTs 28
433703 AA210863 Hs 3532 nemo-like kinase 28
448912 D83781 Hs 22559 KIAA0197 protein 28
405621 28
430687 BE274217 Hs 249247 heterogeneous nuclear protein similar to 28
450400 AI694722 Hs 279744 ESTs 28
456844 AI264155 Hs 152981 CDP-dixylglycerol synthase (phosphalida 28
418342 BE002723 Hs 226627 leptm rxeptor 28
420756 AA411800 Hs 189900 ESTε 28
423532 BE090503 gb RC6-BT0717-110400 011-F11 BT0717 Homo 28
440320 AA879294 gb nw86e09 s1 NCI_CGAP_Pr12 Homo sapiens 28
457314 AA479597 Hs 193669 hypothetical protein DKFZp586J11l9 28
439831 AW136488 Hs 25545 ESTs 28
425661 AL133627 Hs 158923 Homo sapiens mRNA, cDNA DKFZp434K0722 (f 28
407949 W21874 Hs 247057 ESTs, Weakly similar to 2109260A B cell 28
418658 AW874263 Hs 32468 ESTs 28
409978 D31897 Hs 57714 double C2-lιke domains, alpha 28
421340 F07783 Hs 1369 decay accelerating fxtor for complement 28
449071 NM.005872 Hs 22960 breast carcinoma amplified sequence 2 28
409241 AF070602 Hs 51649 Homo sapiens clone 24504 mRNA sequence 28
448219 AA228092 Hs 42656 KIAA1681 protein 28
408936 AL138043 Hs 293549 ESTs 28
410784 AW803201 gb IL2-UM0077-070500 080 E06 UM0077 Homo 28
426471 M22440 Hs 170009 transforming growth factor, alpha 28
454455 AW752710 gb IL3 CT0219 281099 024-A03 CT0219 Homo 28
455310 AW893961 gb RC4-NN0027-060400-011-d11 NN0027 Homo 28
401335 27
436577 W84774 Hε 17643 ESTs 27
409519 AA075368 gb zm86h10 r1 Stratagene ovanan cancer 27
421003 T72080 Hs 95667 F-box protein 30 27
429593 AK000332 Hs 209927 Homo sapiens cDNA FLJ20325 fis, clone HE 27
450434 AA166950 Hs 195870 hypothetical protein FLJ 14991 27
436007 AI247716 Hs 232168 ESTs 27
408874 AW818091 Hs 252730 ESTs 27
418036 Z37976 Hs 83337 latent transforming growth factor beta b 27
435625 H50654 Hs 113999 ESTs 27
435766 R11673 Hs 186498 ESTs 27
410327 T33130 Hs 301746 RAP2A, member of RAS oncogene family 27
416805 F13271 Hs 79981 Human clone 23560 mRNA sequence 27
417177 NM.004458 Hs 81452 fatty-xid Coenzyme A ligase long-chain 27
423020 AA383092 Hs 1608 replication protein A3 (14kD) 27
427134 AA398409 Hs 173561 EST 27
428137 AA421792 Hs 170999 ESTs 27
429710 AI337113 Hs 146025 hypothetical protein FU23594 27
430844 T94960 gb ye38d07 r1 Stratagene lung (937210) H 27
417576 AA339449 Hs 82285 phosphoπbosylglyciπamide formyltraπsfer 27
441928 AI370188 Hs 211454 ESTs 27
409721 AW887732 Hs 257861 ESTs 27
427112 Z32887 Hs 290951 ESTs 27
403776 27
420159 AI572490 Hs 99785 Homo sapiens cDNA FLJ21245 fis, clone C 27
427839 AA608823 Hs 98244 ESTε 27
432837 AA310693 Hs 87329 HSPC072 protein 27
438782 AA828380 Hs 126733 ESTs 27
449396 BE169100 Hs 195029 ESTs 27
458043 AW979009 Hs 326108 ESTs 27
438171 AW976507 Hs 293515 ESTs 27
452959 AI933416 Hs 189674 ESTs 27
439556 AI623752 Hs 163603 ESTs 27
446152 AI292036 Hs 150028 ESTs 27
434803 AW974640 Hs 303413 ESTs 27
407771 AL138272 Hs 62713 ESTs 27
411069 AL133092 Hs 68055 hypothetical protein DKFZp434l0428 27
417543 AA203620 Hs 110153 ESTs 27
401517 27
403677 27
416337 H48713 gb yq78d02 r1 Soares fetal liver spleen 27
423401 NM.001992 Hs 128087 coagulation fxtor II (thrombin) rxepto 27
446800 AI341635 Hs 156486 i ESTs 27
457906 AW975939 Hs 15329G I Homo εapιens cDNA FLJ14318 fis, clone PL 27
452277 AL049013 Hs 28783 KIAA1223 protein 27
416913 AW934714 gb RC1-DT0001-031299 011 a11 DT0001 Homi 27
416370 N90470 Hs 203697 ' ESTε, Weakly similar to I38022 hypotheti 27 408715 AA768873 Hs 112250 hypothetical protein FLJ23518 27
410743 AA089474 Hs 272153 ESTs 27
427138 N77624 Hs 173717 phosphatidic acid phosphatase type 2B 27
436260 BE172762 Hs 292710 ESTs, Weakly similar to ALU5.HUMAN ALU S 27
427565 AI287280 Hs 97933 ESTs, Weakly similar to T46370 hypotheti 27
406092 27
410008 AA079552 gb zm20h12 s1 Stratagene pancreas (93720 27
438504 AW665281 Hs 224625 ESTs 27
414783 AW069569 Hs 278270 unactive progesterone receptor, 23 kD 27
411479 AW848047 gb IL3-CT0214-291299 052-A12 CT0214 Homo 27
418686 Z36830 Hs 87268 annexm A8 27
413795 AL040178 Hs 142003 ESTs 27
457528 AW973791 Hs 292784 ESTs 27
444230 H95537 Hs 146067 ESTs 27
403760 27
416624 H69044 gb yr77h05 s1 Soares fetal liver spleen 27
428904 A1312526 Hs 46640 ESTs 27
446311 AW007294 Hs 149795 ESTs, Moderately similar to ALULHUMAN A 27
458638 N78553 Hs 282204 nucleosomal binding protein 1 27
459267 AJ003631 gb AJ003631 Selected chromosome 21 cDNA 27
424834 AK001432 Hs 153408 Homo sapiens cDNA FLJ10570 fis, clone NT 27
433906 AI167816 Hs 43355 ESTs 27
428966 AF059214 Hs 194687 cholesterol 25-hydroxyIase 27
446554 AA151730 Hs 301789 nudix (nucleoside diphosphate linked moi 27
446035 NM 006558 Hs 13565 Sam68 like phosphofyrosme protein, T-ST 27
421585 U95626 Hs 302043 chemokine (C-C motif) rxeptor like 2 27
445158 AI992108 Hs 127206 ESTs 27
421175 AI879099 Hs 102397 GIOT-3 for gonadotropin inducible transc 27
401793 27
410181 AI468210 Hs 261285 pleiotropio regulator 1 (PRL1, Arabidops 27
427038 NM 014633 Hs 173288 KIAA0155 gene product 27
451343 AW975057 Hs 293353 ESTs 27
455982 BE179015 gb RC3-HT0612-080500013 h10 HT0612 Homo 27
438475 W03856 Hs 13188 ESTs, Highly similar to Gene product wit 27
455571 BE003714 gb QV3-BN0096-200400-161-a01 BN0096 Homo 27
426298 AW965058 Hε 111583 ESTs, Weakly similar to I38022 hypotheti 27
407930 AA045847 Hs 188361 Homo εapiens cDNA FLJ12807 fis, clone NT 27
453891 AB037751 Hs 36353 Homo sapiens mRNA full length insert cDN 27
451487 AA018072 gb ze51g02 r1 Soares retina N2b4HR Homo 27
418269 AA806113 Hs 189025 ESTs 27
419196 AF110908 Hs 297660 TNF rxeptor-assxiated factor 3 27
459160 AI904723 gb CM BT066-120298 092 BT066 Homo sapien 27
441963 AI733307 Hs 128002 ESTs 27
440273 AI805392 Hε 325335 Homo εapiens cDNA FLJ23523 fis, clone L 27
426902 AH 25334 Hε 97408 ESTs 27
414271 AK000275 Hs 75871 protein kinase C binding protein 1 27
453313 BE005771 Hs 153746 hypothetical protein FLJ22490 27
445265 AI218295 Hs 144942 ESTs 27
422988 AW673847 Hs 97321 ESTs 27
428613 AB037749 Hs 186928 KIAA1328 protein 27
444619 BE538082 Hs 8172 ESTs, Moderately similar to A46010 X-lm 27
457300 AW297436 Hs 158849 Homo sapiens cDNA FLJ21663 fis, clone C 27
402800 27
425071 NM 013989 Hs 154424 deiodiπase, lodothyromne, type II 27
414729 BE466928 Hs 281901 ESTs 27
453716 AA037675 Hs 152675 ESTs 27
452693 T79153 Hs 48589 zinc finger protein 228 27
439818 AL360137 Hs 19934 Homo sapiens mRNA full length insert cDN 27
443305 AI050693 Hs 133318 ESTs 27
416709 R99369 Hs 283108 hemoglobin, gamma G 27
419077 AA233885 Hs 164526 ESTs 27
453878 AW964440 Hs 19025 DC32 27
445660 AI702668 Hs 201855 ESTs 27
446817 A1700684 Hs 134166 ESTs 27
442137 AA977235 Hs 128830 ESTs, Weakly similar to Z192.HUMAN ZINC 26
410406 AI969703 Hs 1466 glycerol kinase 26
442242 AV647908 Hs 90424 Homo sapiens cDNA FLJ23285 fis, clone H 26
407830 NM.001086 Hs 587 arylxetamide dexetylase (eεterase) 26
415138 C18356 Hs 295944 tisεue fxtor pathway inhibitor 2 26
407055 X89211 gb H εapienε DNA for endogenous retrovir 26
408812 BE397160 Hs 254763 I ESTs, Weakly similar to A42442 integπn 26
440310 AA878939 Hs 12540e i ESTs 26
425659 AK000590 Hs 158836 i hypothetical protein FLJ 20583 26
418217 AI910647 Hs 13442 ESTs 26
428667 AI375550 Hs 74407 nucleolar protein p40, homolog of yeast 26
414573 AI821846 Hs 71999 ESTs 26
420000 AB036063 Hs 94262 p53-ιnducιble ribonucleotide redu ase s 26
452821 AW471181 Hs 160874 ESTs 26
440138 AB033023 Hs 318127 hypothetical protein FLJ10201 26
428483 AI908539 Hs 321444 KIAA0344 gene product 26
441350 AB020690 Hs 7782 paraneoplaεtic antigen MA2 26
405059 26
425178 H16097 Hs 161027 ESTs 26 442952 AI743261 Hs 131860 ESTs 26
428692 AI372822 Hs 110103 RNA polymerase 1 transcription factor RR 26
456179 H75490 Hs 271930 ESTs 26
414136 AA812434 Hs 119023 SMC2 (structural maintenance of chromoso 26
459456 AA486036 Hs 190124 ESTs 26
425527 AL162032 Hs 158258 Homo sapiens mRNA, cDNA DKFZp434B1272 (f 26
424711 NM 005795 Hs 152175 calcitonin receptor-like 26
417956 AA210704 Hs 190465 ESTs 26
420621 AA278808 gb zs79c09r1 NCI.CGAP.GCB1 Homo εapiens 26
425698 NM 016112 Hs 159241 polycystic kidney disease 2 like 1 26
438295 AI394151 Hs 37932 ESTs 26
445550 AI242754 Hs 137306 ESTs 26
450469 AI955049 Hs 281326 ESTs 26
458804 AL157625 gb DKFZp761L2016_r1 761 (synonym hamy2) 26
443657 R14973 gb yf42f10 s1 Soares fetal liver spleen 26
429250 H56585 Hs 198308 tryptophan rich baεic protein 26
437906 AA771704 Hs 194626 ESTε 26
426775 AA384564 Hs 108829 ESTs 26
443372 AI792557 Hs 133107 ESTs 26
453785 A1368236 Hs 283732 ESTs, Moderately similar to ALULHUMAN A 26
425465 L18964 Hs 1904 protein kinase C, iota 26
422746 NM.004484 Hs 119651 glypican 3 26
413450 Z99716 Hs 75372 N-acetylgalactosaminidase, alpha 26
424527 AW138558 Hs 267158 ESTs, Weakly similar to I54374 gene NF2 26
414180 AI863304 Hs 120905 Homo sapiens cDNA FLJ11448 fis, clone HE 26
411402 BE297855 Hs 69855 NRAS related gene 26
445264 AI218263 Hs 323472 EST 26
458861 AI630223 gb ad06g08 r1 Proliferating Erythroid Ce 26
415227 AW821113 Hs 72402 ESTs 26
435429 AW592035 Hs 254414 ESTs, Weakly similarto 1805195B RNA bin 26
434445 AI349306 Hs 11782 ESTs 26
448570 AI923944 Hs 30913 ESTs 26
452381 H23329 Hs 290880 ESTs, Weakly similar to ALU1 HUMAN ALU S 26
422879 AI241409 Hs 188092 ESTs 26
409026 AL137554 Hs 49927 protein kinase NYD SP15 26
425717 X07282 Hs 171495 retinoic acid rxeptor, beta 26
429127 AA749382 Hs 118797 ubiquitin-conjugating enzyme E2D 3 (homo 26
438298 H23542 Hs 181788 ESTs 26
442717 R88362 Hs 180591 ESTs, Weakly similar to T23976 hypotheti 26
443555 N71710 Hs 21398 ESTs, Moderately similar to A Cham A, H 26
444517 AI939339 Hs 146883 ESTs 26
451813 NM 016117 Hs 27182 phospholipase A2-actιvatιng protein 26
452453 A1902519 gb QV-BT009-101198 051 BT009 Homo sapien 26
455870 AW452631 Hs 313803 ESTs, Highly similar to AF157833 1 noncl 26
437939 AW298600 Hs 141840 ESTs, Weakly similarto S59501 mterfero 26
430719 AA488988 Hs 293796 ESTs 26
452864 AA033714 Hs 287629 hypothetical protein FLJ14260 26
432095 AW022273 Hs 105769 ESTs 26
431086 AI829682 Hs 211561 ESTs 26
407783 AW996872 Hs 172028 a disintegnn and metalloprotemase doma 26
423952 AW877787 Hs 136102 KIAA0853 protein 26
453403 BE466639 Hs 61779 Homo sapiens cDNA FLJ13591 fis, clone PL 26
408172 W02488 Hs 46039 phosphoglycerate mutase 2 (muscle) 26
430933 AW863635 gb MR3 SN0010-270300-103-h02 SN0010 Homo 26
420691 AA829433 Hs 275343 ESTs 26
429761 AI276780 Hs 135173 ESTs 26
437958 BE139550 Hs 121668 ESTs, Moderately similar to PC4259 fem 26
407494 U10072 gb Human forkhead family (AFX1) mRNA, pa 26
436464 AI016176 Hs 269783 ESTs, Weakly similar to ALULHUMAN ALU S 26
407137 T97307 gb ye53h05 s1 Soareε fetal liver spleen 26
446223 BE300091 Hs 119699 hypothetical protein FLJ12969 26
438647 AA813118 Hs 163230 ESTs 26
438192 AI859065 Hs 337620 Homo sapienε AFG3L1 isoform 1 mRNA, part 26
417218 AA005247 Hs 285754 met proto-oncogene (hepat∞yte growth fa 26
440460 H92571 Hs 234478 Homo sapienε cDNA FLJ22648 fis, clone H 26
414612 BE274552 Hs 76578 protein inhibitor of activated STAT3 26
428170 H05530 Hs 12565 ESTs 26
457343 NM.013936 Hs 247862 olfactory receptor, family 12, subfamily 26
424020 R76946 Hs 39738 ESTs 26
455226 AW902103 gb QVO-NN1022-120500-220-C07 NN1022 Homo 26
411965 BE467339 Hs 280115 ESTs 26
432656 NM 000246 Hs 3076 MHC claεs II traπsxtivator 26
455488 AA102322 gb zl90f03 r1 Stratagene colon (937204) 26
434340 AI193043 Hs 128685 ESTs, Weakly similar to T17226 hypotheti 26
404285 26
418744 AI887288 Hε 196379 ESTs, Weakly similar to putative p150 [H 26
454714 AW815098 gb QV4-ST0212-091199 023410 ST0212 Homo 26
429828 AB019494 Hs 225767 1DN3 protein 26
436387 AA714760 Hs 240075 Homo sapienε cDNA FLJ13234 fis, clone OV 26
448587 AI539652 Hs 28338 KIAA1546 protein 26
432865 AI753709 Hs 152484 ESTs, Weakly similar to I38022 hypotheti 26
440479 AA886461 Hs 208161 ESTs 26
443160 AI467915 Hs 36053 ESTs 26 428978 AA442784 Hs 125445 I ESTs 25
444670 H58373 Hs 332938 hypothetical protem MGC5370 25
453459 BE047032 Hs 257789 ESTs 25
418122 R42778 Hs 22217 Homo sapiens clone IMAGE 32106 mRNA seq 25
442875 BE623003 Hs 23625 Homo sapiens clone TCCCTA00142 mRNA sequ 25
414373 AW162907 Hs 75969 proline πch protein with nuclear target 25
458760 AI498631 Hs 111334 ferπtin, light polypeptide 25
434131 A1858275 Hs 143659 ESTs 25
441805 AA285136 Hs 301914 neuronal spxific transcription factor D 25
457292 AI921270 Hε 334882 hypothetical protein FLJ14251 25
417351 T90278 Hs 15049 ESTs 25
409695 AA296961 gb EST112514 Adrenal gland tumor Homo sa 25
432824 AK001783 Hs 279012 hypothetical protein FLJ10921 25
438038 AI732629 Hs 194161 ESTs, Weakly similar to TA2R HUMAN, BETA 25
454836 AW833711 gb QV4-TT0008 251199 043-e11 TT0008 Homo 25
453919 AW959912 Hs 7076 KIAA1705 protein 25
422487 AJ010901 Hs 198267 mucin 4, tracheobronctiial 25
408727 AL137259 Hs 47115 hypothetical protein DKFZp434D0513 25
427491 R43279 Hε 22574 ESTs, Weakly similar to I38022 hypotheti 25
435102 AW899053 Hs 76917 F box only protein 8 25
409617 BE003760 Hs 55209 Homo sapiens mRNA, cDNA DKFZp434K0514 (f 25
455866 BE149024 gb CM0-HT0249 291099 084-c04 HT0249 Homo 25
432887 AI926047 Hs 162859 ESTs 25
407756 AA116021 Hs 38260 ubiquitin spxific protease 18 25
401078 25
410365 AI287518 Hs 62669 Homo sapiens mRNA cDNA DKFZp586D0923 (f 25
425201 AA352111 gb EST60061 Activated T-cells XX Homo sa 25
457112 AW772449 Hs 268081 ESTs, Weakly similar to ALULHUMAN ALU S 25
455252 AW876627 gb RC3-PT0028-120200-013-d11 PT0028 Homo 25
444542 AI161293 Hs 280380 aminopeptidase 25
419249 X14767 Hs 89768 gamma aminobutyπc acid (GABA) A recepto 25
428497 BE010877 Hs 98584 ESTs 25
457336 AW969657 Hs 291029 ESTs 25
427621 BE621182 Hs 179882 hypothetical protein FLJ 12443 25
423782 A1472209 Hs 323117 ESTs 25
430403 AF039390 Hs 241382 tumor necrosis factor (ligand) superfami 25
429927 NM.001115 Hs 2522 adeπylate cyclase 8 (brain) 25
408562 AI436323 Hs 31141 Homo sapiens mRNA for KIAA1568 protein, 25
417137 U46265 Hs 81281 mitochondnal nboεomal protein S21 25
436787 AA908554 Hs 192756 ESTs 25
440331 AL046412 Hs 202151 ESTs 25
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 25
417169 R13550 Hs 246773 ESTε 25
453020 AL162039 Hs 31422 Homo sapiens mRNA, cDNA DKFZp434M229 (fr 25
455286 BE144384 gb MRO-HT0166-191199 004-O11 HT0166 Homo 25
450654 AJ245587 Hs 25275 Kruppel-type zinc finger protein 25
400432 AX015809 Hs 287767 Sequence 8 from Patent WO9950285 25
415747 AA381209 gb EST94257 Activated T-cells I Homo sap 25
446346 AI290205 Hs 309940 ESTs 25
450209 AW008921 Hs 13138 Homo sapiens, clone IMAGE 3448343, mRNA, 25
453202 AW085781 Hs 26270 hypothetical protein FLJ11588 25
425523 AB007948 Hs 158244 KIAA0479 protein 25
433124 U51712 Hs 13775 hypothetical protein SMAP31 25
408741 M73720 Hs 646 carboxypeptidase A3 (mast cell) 25
425657 T89839 Hs 119471 ESTs 25
401254 25
426604 H53354 Hs 97141 ESTs, Weakly similar to hypothetical pro 25
449535 W15267 Hs 23672 low density lipoprotem rxeptor related 25
433138 AB029496 Hs 59729 εemaphoπn εem2 25
425804 BE501698 Hs 258189 ESTε 25
429515 AL031228 Hs 204370 DNA εegment on chromoεome 6 (unique, pse 25
437267 AW511443 Hs 258110 ESTs 25
454305 BE062633 Hs 28338 KIAA1546 protein 25
455631 BE063031 gb MR0 BT0265-231199-002-e09 BT0265 Homo 25
401878 25
450350 T97817 Hs 174880 ESTs 25
436532 AA721522 gb nv54h12 r1 NCI_CGAP_Ew1 Homo εapiens 25
457460 AI143312 Hs 129206 casein kinase 1, gamma 3 25
427304 AA761526 Hs 163853 ESTs 25
419721 NM 001650 Hs 288650 aquapoπn 4 25
431699 NM.001173 Hs 267831 Rho GTPase activating protein 5 25
446252 AI283125 Hs 150009 ESTs 25
421229 AI056590 Hs 7086 hypothetical protein MGC12435 25
434273 AA913143 Hs 26303 ESTs 25
456088 BE177320 Hs 156148 hypothetical protein FLJ13231 25
434353 AA630863 Hs 131375 ESTs, Moderately similar to ALUB_HUMAN l 25
436198 AK001125 Hs 300922 Homo sapienε cDNA FLJ10263 fiε, clone HE 25
452232 AW020603 Hs 158423 radial εpoke protein 3 25
433764 AW753676 Hs 39982 ESTs 25
412050 H96503 Hs 109087 Homo sapiens cDNA FLJ22845 fis, clone K 25
422342 AA309272 gb EST180209 Uver, hepatocellular carci 25
427510 Z47542 Hs 179312 small nuclear RNA activating complex, po 25
428336 AA503115 Hs 183752 microseminoprotein, beta 25 408813 AI580090 Hs 48295 RNA helicase family 25
414109 BE250744 gb 600943376F1 NIH.MGC.17 Homo sapiens c 25
451678 AA374181 Hs 26799 DKFZP564D0764 protein 25
419985 H66373 Hs 15973 ESTs, Highly similar to bA393J163 [H sa 25
417859 T26453 gb AB214F6R Infant brain, LLNL array of 25
434334 AA912476 Hs 116750 Homo sapiens cDNA FLJ13221 fis, clone NT 25
448015 AI458065 Hs 23196 ESTs 25
454190 AW177821 gb IL3-HT0059 180899 007-C05 HT0059 Homo 25
445865 AI262584 Hs 145575 ESTs 25
451800 AW977435 Hs 323867 ESTs 25
456987 AI557290 Hs 173536 ESTs 25
403568 25
435209 AW027809 Hs 187698 Homo εapiens cytomegalovirus partial fus 25
430371 D87466 Hs 240112 KIAA0276 protein 25
418033 W68180 Hs 259855 elongation fxtor-2 kinase 25
412095 AI624707 Hs 5921 Homo sapienε cDNA FLJ21592 fiε, clone C 25
453619 H87648 Hs 33922 Homo sapiens, clone MGC 9084, mRNA, comp 25
431071 AA491379 gb aa65f05 r1 NCI.CGAP.GCB1 Homo sapiens 25
407939 W05608 Hs 312679 ESTs, Weakly similar to A49019 dynein he 25
409045 AA635062 Hs 50094 Homo sapienε mRNA, cDNA DKFZp434O0515 (f 25
444575 AI264847 Hs 22545 Homo sapiens cDNA FLJ12935 fis, clone NT 25
408420 NM.006915 Hs 44766 retinitis pigmentosa 2 (X-lmked rxessi 24
417318 AW953937 Hs 12891 ESTs 24
413382 BE090689 gb RC1-BT0720-280300-011-f08 BT0720 Homo 24
406748 AW339106 Hs 217493 annexm A2 24
445898 AF070623 Hs 13423 Homo sapiens clone 24468 mRNA sequence 24
441817 AW969706 Hs 293332 ESTs 24
450551 AJ010046 Hs 25155 neuroepithelial cell transforming gene 1 24
457940 AL360159 Hs 306517 Homo sapiens TRIpartite motif protein ps 24
446135 AW130288 Hs 170318 hypothetical protein FLJ10147 24
436907 AA737171 Hs 131809 ESTs 24
429399 AA452244 Hs 16727 ESTs 24
448782 AL050295 Hs 22039 KIAA0758 protein 24
434404 AW445034 Hs 256578 ESTs 24
428571 NM 006531 Hs 2291 Probe hTg737 (polycystic kidney disease, 24
448164 R61680 Hs 26904 ESTs, Moderately similar to Z195_HUMAN Z 24
442295 AI827248 Hs 224398 Homo sapiens cDNA FLJ11469 fis, clone HE 24
450705 U90304 Hs 25351 iroquois homeobox protein 5 24
425506 NM 003666 Hs 158205 basic leucine zipper nuclear factor 1 (J 24
423961 D13666 Hs 136348 osteoblast spxific factor 2 (fascidin 24
458986 AI802772 Hs 208655 ESTε 24
443861 AW449462 Hs 134743 ESTε 24
412879 BE092219 gb IL2-BT0734-240400-071-B04 BT0734 Homo 24
415250 F02614 Hs 27319 ESTε 24
434627 AI221894 Hs 39311 ESTε 24
443919 AI091284 Hs 135224 ESTs, Weakly similar to A47582 B-cell gr 24
440400 AA994364 Hs 125594 ESTs, Weakly similar to T25472 hypotheti 24
400385 NM 020389 Hs 283104 putative capxitative calcium channel 24
411322 AW887330 Hs 172405 cell division cycle 27 24
434638 H50758 gb yp86e06 ri Soares fetal liver spleen 24
435559 AF2091S8 Hs 42636 zinc finger protein 277 24
447849 AI538147 Hs 164277 ESTs 24
448005 AW207437 Hs 170378 ESTs 24
454201 AB023181 Hs 44131 KIAA0974 protein 24
456869 BE467812 Hs 154294 discs, large (Drosophila) homolog 1 24
449486 AI652715 Hs 270811 ESTs 24
421516 AI362418 Hs 105379 FT005 protein 24
412167 AW897230 gb CM0-NN0057-150400-335-a11 NN0057 Homo 24
426910 AA470023 Hs 190089 ESTs, Moderately similar to ALULHUMAN A 24
429673 AA884407 Hs 211595 protein tyrosine phosphatase, non-rxept 24
400641 24
430576 AA767125 Hs 293574 ESTs 24
434423 NM 006769 Hs 3844 UM domain only 4 24
412104 AW205197 Hs 240951 Homo sapienε, Similar to RIKEN cDNA 2210 24
441499 AW298235 Hs 101689 ESTs 24
418113 AI272141 Hs 83484 SRY (sex determining region Y)-box 4 24
417819 AI253112 Hs 133540 ESTs 24
431728 NM 007351 Hs 268107 multimenn 24
425025 AW953168 Hs 12407 ESTs 24
421168 AF182277 Hs 330780 cytochrome P450, subfamily IIB (phenobar 24
409432 D49372 Hs 54460 small inducible cytokine subfamily A (Cy 24
408867 AA437199 Hs 656 cell division cycle 25C 24
439446 AI927629 Hs 57873 ESTs 24
445038 AI635444 Hs 143917 dJ467N11 1 protein 24
450682 Z42993 Hs 25320 Homo sapiens clone 25142 mRNA sequence 24
455107 BE154113 gb PM1-HT0340 151299 003-a08 HT0340 Homo 24
458624 AI362790 Hs 278639 KIAA1684 protein, likely homolog of mous 24
449523 NM 000579 Hs 54443 chemokine (C-C motif) rxeptor 5 24
428784 Y12851 Hs 193470 puπnergic rxeptor P2X, ligand-gated 24
453864 AW021407 Hs 21068 hypothetical protein 24
426497 AA379913 gb EST92807 Skin tumor I Homo sapiens cD 24
418203 X54S42 Hs 83758 CDC28 protein kinase 2 24
426603 AA382291 gb EST95683 Testis I Homo sapiens cDNA 5 24 447357 AI375922 Hs.159367 ESTs 2.4
452631 AI188658 Hs.87496 ESTs 2.4
405041 2.4
405472 2.4
409744 AW675258 Hs.56265 Homo sapieπε mRNA; cDNA DKFZp586P2321 (f 2.4
433868 AA612960 Hs.337300 ESTs 2.4
437119 AI379921 Hs.177043 ESTs 2.4
455114 AW857121 gb:RC1-CT0302-040400-01 -a12 CT0302 Homo 2.4
431613 AA018515 Hs.264482 Homo sapiens mRNA; cDNA DKFZp761 A0411 (f 2.4
434936 A1285970 Hs.183817 ESTs 2.4
408918 BE218603 Hs.279708 ESTs 2.4
444106 AI123922 Hs.138215 Homo sapiens cDNA FLJ11400 fis, clone HE 2.4
416580 T61572 Hs.79385 Human clone 23574 mRNA sequence 2.4
430299 W28673 Hs.106747 serine carboxypeptidase 1 precursor prot 2.4
446659 AI335361 Hs.226376 ESTs 2.4
418636 AW749855 gb:QV4-BT0534-281299-053-O05 BT0534 Homo 2.4
434995 AW974995 gb:EST387100 MAGE resequences, MAGN Homo 2.4
438005 BE151746 gb:PM1-HT0305-061299-003-a06 HT0305 Homo 2.4
444755 AA431791 Hs.113823 ClpX (caseinolyfic protease X, E. coli) 2.4
427131 AA448460 Hs.112017 GE36 gene 2.4
442039 AW276240 Hs.128352 ESTs 2.4
448595 AB014544 Hs.21572 KIAA0644 gene product 2.4
432949 AA570749 Hs.298866 ESTs 2.4
444314 AI140497 gb;ow76b09.s1 Soares fetal liver spleen 2.4
417420 T85150 Hs.268814 ESTs 2.4
427551 T96203 gb:ye48b07.r1 Soares fetal liver εpleen 2.4
420057 AA806899 Hs.184387 ESTs 2.4
434950 AW974892 gb;EST386997 MAGE resequences, MAGN Homo 2.4
425497 AA524596 gb:πh34b02.s1 NCI_CGAP_Pr3 Homo sapiens 2.4
438214 H06076 Hs.26320 TRABID protein 2.4
416100 H18700 Hs.268799 ESTs 2.4
419637 W27493 gb:31h10 Human retina cDNA randomly prim 2.4
449432 AW451361 Hs.196529 ESTε 2.4
454403 BE065985 gb:RC3-BT0319-120200-014-a09 BT0319 Homo 2.4
419179 AW275291 Hs.113009 hypothetical protein FLJ22527 2.4
436391 AJ227892 Hs.146274 ESTε 2.4
449511 AI436187 Hs.296261 guanine nucleotide binding protein (G pr 2.4
447499 AW262580 Hs.147674 protocadherin beta 16 2.4
407244 M10014 Hs.75431 fibrinogen, gamma polypeptide 2.4
412877 BE011168 gb:PM3-BN0218-100500-003-d08 BN0218 Homo 2.4
435985 AA703154 Hs.191934 ESTs 2.4
440674 BE561546 gb:601347208F1 NIH MGC 8 Homo sapiens cD 2.4
446476 AW294072 Hs.141376 ESTs 2.4
444100 AA383343 Hs.22116 CDC14 (cell division cycle 14, S. cerevi 2.4
435731 AA699581 Hs.186811 ESTs 2.4
437105 AA744554 Hs.222127 ESTs 2.4
406091 2.4
457024 AA397546 Hs.119151 ESTs 2.4
404249 2.4
419556 U29615 Hε.91093 chltinase 1 (chitotriosidase) 2.4
424943 AU077260 Hε.153924 death-ass∞iated protein kinase 1 2.4
444229 AV648613 Hs.282397 ESTε 2.4
404860 2.4
432223 AA333283 Hs.121001 Homo εapieπs, clone IMAGE;3460280, mRNA 2.4
410467 AF102546 Hs.63931 dxhshund (Drosophila) homolog 2.4
420843 H96982 Hs.42321 ESTs 2.4
434927 H46612 Hs.293815 Homo sapiens HSPC285 mRNA, partial eds 2.4
413642 BE154837 gb:PM1-HT0345-121199-001-c08 HT0345 Homo 2.4
436998 AA745625 Hs.291414 ESTs, Weakly similar to ALU8.HUMAN ALU S 2.4
441235 AI884586 Hs.135570 Homo sapiens cDNA; FLJ21268 fis, clone C 2.4
445748 U80766 Hε.13252 Human EST clone 22453 mariner transposoπ 2.4
451018 AW965599 Hs.247324 mitochondrial ribosomal protein S14 2.4
409073 AA063458 gb:zf71a07.s1 Soares pineaLgland N3HPG 2.3
418782 AI792648 Hs.14665 ESTs 2.3
447870 BE139479 Hs.161492 ESTs 2.3
437370 AL359567 Hs.161962 Homo sapiens mRNA; cDNA DKFZp547D023 (fr 2.3
424765 AA428211 Hs.284256 hypothetical protein FLJ14033 similar to 2.3
407385 AA610150 Hs.272072 ESTs, Weakly similar to I38022 hypotheti 2.3
424049 AB014524 Hs.138380 KIAA0624 protein 2.3
425398 AL049689 Hs.156369 hypothetical protein similar to tenascin 2.3
430702 U56979 Hs.250651 H fxtor 1 (complement) 2.3
409620 AA076278 Hs.13277 hypothetical protein FLJ22054 2.3
441675 AI914329 Hs.5461 ESTs 2.3
430884 AF053748 Hs.248114 glial cell derived neurotrophic factor 2.3
445523 Z30118 Hs.293788 ESTs, Moderately similar to unnamed prot 2.3
416972 BE019670 gb:bb28c01.x1 NIH.MGC.5 Homo sapiens cDN 2.3
443547 AW271273 Hs.23767 hypothetical protein FLJ12666 2.3
417583 AA668782 Hs.191284 ESTs, Weakly similar to ALULHUMAN ALU S 2.3
422182 AL043892 Hs.180582 Homo sapiens cDNA; FLJ21836 fis, clone H 2.3
404513 2.3
410999 AW813004 gb:RC3-ST0186-230300-019-h02 ST0186 Homo 2.3
448506 AI524673 Hs.38170 ESTs 2.3
434811 AW971205 Hs.114280 ESTs 2.3 457065 A1476318 Hs 192480 ESTs 23
407945 X69208 Hs 606 ATPase, Cu++ transporting alpha polypep 23
419865 NM 007020 Hs 93502 U1 snRNP binding protein homolog (70kD) 23
423596 AA328195 Hs 234101 ESTs Weakly similar to CTL1 protein [H 23
455807 BE141140 gb MR0 HT0075 021299 006-d07 HT0075 Homo 23
435867 AA954229 Hs 114052 ESTs 2 3
440196 N72847 Hs 125221 ESTs 2 3
401213 23
407291 AA001464 gb ze45b01 r1 Soares retina N2b4HR Homo 23
442490 AW965078 Hs 30212 thyroid rxeptor interacting protein 15 23
452943 BE247449 Hs 31082 hypothetical protein FLJ10525 23
438138 R98299 Hs 177502 ESTs 23
440283 AI732892 Hs 190489 ESTs 23
447039 AV661798 Hs 282915 ESTs 23
412777 AI335773 Hs 270123 ESTs 23
421424 AW452690 Hs 258775 ESTs 23
406673 M34996 Hs 198253 major histocompatibility complex, class 2 3
440555 D31292 Hs 6853 hypothetical protein FLJ22167 23
451516 AI800515 Hs 12024 ESTs 23
424690 BE538356 Hs 151777 eukaryotic translation initiation factor 2 3
421046 AA810854 Hs 89081 ESTs 23
423604 AA486585 Hs 258901 ESTs 23
409029 BE087807 gb QV1-BT0681-290400-181-g02 BT0681 Homo 23
444206 AW301017 Hs 146492 ESTs 23
451836 T63673 Hs 173220 ESTε 23
454784 AW820626 gb RC0-ST0299 190100 012-e10 ST0299 Homo 23
423673 BE003054 Hs 1695 matrix metalloproteinase 12 (macrophage 23
436671 AW137159 Hs 146151 ESTs 23
434988 AI418055 Hs 161160 ESTs 23
452862 AW378065 Hs 8687 ESTs 23
439480 AL038511 Hs 125316 ESTs, Weakly similar to S33990 finger pr 23
410606 AW418779 Hs 114889 ESTs 23
426535 AU077012 Hs 288582 ESTs, Weakly similar to ubiquitous TPR m 23
432239 X81334 Hs 2936 matrix metalloproteinase 13 (collagenase 2 3
430217 N47863 Hs 336901 ribosomal protein S24 23
417479 AI057052 Hs 133554 ESTs, Weakly similar to Z195 HUMAN ZINC 23
421253 AI188102 Hs 31028 ESTs 23
438180 AA808189 Hs 272151 ESTs 23
439715 AA524504 Hs 42612 ESTs, Weakly similar to ALULHUMAN ALU S 23
441398 AA932398 Hs 292036 ESTs, Weakly similar to B34087 hypotheti 23
443055 AV653742 Hs 15536 hypothetical protein DKFZp761J139 2 3
413585 AI133452 Hs 75431 fibππogen, gamma polypeptide 23
448831 AL080123 Hs 22182 zinc finger protein 23 (KOX 16) 23
412953 Z45794 Hs 238809 ESTs 23
430789 AA632577 Hs 310235 ESTs, Weakly similar to I78885 εenne/th 23
422757 AI909935 Hs 65551 Homo εapienε, Similar to DNA segment, Ch 23
423003 AL120077 Hs 122967 kelch (Drosophila) like 2 (Mayven) 23
428595 AB037795 Hs 186547 KIAA1374 protein 23
437887 AA811524 Hs 29263 hypothetical protein FLJ11896 23
447720 AL038765 Hs 161304 ESTs 23
452355 N54926 Hs 29202 G protein-coupled rxeptor 34 1 23
408374 AW025430 Hs 155591 forkhead box F1 23
440381 AA917808 Hs 190495 ESTs 23
425478 AB007953 Hs 268840 ESTs 23
432231 AA339977 Hs 274127 CLST 11240 protein 23
431757 AA196930 Hs 268526 Homo sapiens chromosome 21 22 1 anonymou 23
417517 AF001176 Hs 82238 POP4 (processing of precursor , S cerev 23
452837 AL121053 Hs 5534 Homo sapienε cDNA FLJ12961 fis, clone NT 23
417426 NM.O02291 Hs 82124 laminin, beta 1 23
423739 AA398155 Hs 97600 ESTs 23
416847 L43821 Hs 80261 enhancer of filamentation 1 (cas-like do 23
425876 AW005887 Hs 234058 ESTs 23
457411 AW085961 Hs 130093 ESTs 23
413136 BE066941 gb PM0 BT0340-091299 002-.11 BT0340 Homo 23
420313 AB023230 Hs 96427 KIAA1013 protein 23
421751 AW813731 Hs 159153 ESTs, Moderately similarto S65657 alpha 23
424827 AI057094 Hs 96867 Homo sapiens cDNA FLJ23155 fis, clone L 23
436331 AI239495 Hs 120189 ESTs 23
439275 AF086093 Hs 141566 ESTs 23
449272 AW137656 Hs 197645 ESTs 23
454352 AW389668 gb RC2-ST0168 071299 013406 ST0168 Homo 23
428758 AA433988 Hs 98502 hypothetical protein FU14303 23
407242 M18728 gb Human nonspxific crossrexting antig 23
445326 AI220072 Hs 165893 ESTs 23
423778 Y09267 Hs 132821 flavin containing monooxygenase 2 23
452607 AI160029 Hs 61438 ESTs 23
423161 AL049227 Hs 124776 Homo sapiens mRNA, cDNA DKFZp564N1116 (f 23
418851 AI417828 Hs 192435 ESTs 23
458332 AI000341 Hs 220491 ESTs 23
432565 AA553477 Hs 152428 ESTs 23
437511 AI807500 Hs 125247 ESTs 23
430957 AI937072 Hs 55043 Homo sapiens cDNA FLJ 13277 fis, clone OV 23
425898 AA365649 Hs 269478 ESTs, Weakly similar to PC4259 ferntiπ 23 448225 A1476429 Hs 19238 ESTs 23
408955 BE315170 Hs 8087 NAG-5 protein 23
416509 N57713 Hs 260899 ESTs, Moderately similar to ZN91.HUMAN Z 23
419699 AA248998 Hs 173044 ESTs Weakly similar to I38022 hypotheti 23
428976 AL037824 Hs 194695 ras homolog gene family, member I 23
458925 R15891 Hs 281587 Human (clone CTG-A4) mRNA sequence 23
440348 AW015802 Hs 47023 ESTs 23
436340 R42246 Hs 21606 ESTs 23
444190 A1878918 Hs 10526 cysteine and glycine-πch protein 2 23
438462 AI624122 Hs 89578 general transcription factor HH, polype 23
411124 AW196937 Hs 53929 ESTs, Weakly similar to ALUB_HUMAN "" 23
442138 AA445973 Hs 13303 Homo sapiens cDNA FLJ21784 fis, clone H 23
412505 AA974491 Hs 21734 ESTs 23
418236 AW994005 Hs 337534 ESTs 23
423582 BE000831 Hs 23837 Homo εapieπs cDNA FLJ11812 fis, clone HE 23
453901 BE065902 gb RC2-BT0318 150200 011 b09 BT0318 Homo 23
418565 AK001529 Hs 86149 phosphomositol 3-phosphate binding prat 23
433404 T32982 Hs 102720 ESTs 23
409517 X90780 Hs 120036 troponin I, cardiac 23
439871 R88518 Hs 46736 hypothetical protein FLJ 23476 23
445641 AI245987 Hs 149442 ESTs 23
449276 AW241510 Hs 252713 ESTε 23
436547 AJ297351 Hs 30824 leucine zipper transcription factor like 23
437770 AA767881 Hs 122897 ESTs 23
409064 AA062954 Hs 141883 ESTε 23
442607 AA507576 Hs 288361 Homo εapienε cDNA FLJ22696 fis, clone H 23
449869 W57990 Hs 60059 Homo sapiens cDNA FLJ11478 fis, clone HE 23
422108 AA297914 Hs 111749 postmeiotic segregation increased (S ce 23
418251 AA832123 Hs 177723 ESTs 23
432005 AA524190 Hs 120777 ESTε, Weakly similar to ELL2_HUMAN RNA P 23
413638 H71252 gb ys12h12 s1 Soares fetal liver spleen 23
415980 R52414 gb yg80b05 r1 Soares infant brain 1NIB H 23
449232 AW192780 Hs 196080 ESTs 23
430882 BE174240 Hs 79024 heterogeneous nuclear πbonucleoprotein 23
454389 AW752571 gb IL3-CT0213-170100-055-F02 CT0213 Homo 23
438089 W05391 Hs 83623 nuclear rxeptor subfamily 1 , group 1, m 23
400238 23
404488 23
407809 AW082279 Hs 244106 ESTs 23
412303 AW936336 gb QV4-DT0021-281299070-g11 DT0021 Homo 23
420478 AA521259 Hs 193796 ESTs 23
422711 D60641 Hs 21739 Homo sapiens mRNA, cDNA DKFZp586l1518 (f 23
424073 U03493 Hs 138959 gap junction protein, alpha 7, 45kD (con 23
426567 AA381579 Hs 182962 ESTs 23
435708 AI362949 Hs 75169 ESTs 23
441417 AI733297 Hs 144474 ESTs 23
445117 AI208754 Hs 147369 ESTs 23
447197 R36075 gb yfι88b01 s1 Soares plxenta Nb2HP Homo 23
434228 Z42047 Hs 283978 Homo sapiens PR02751 mRNA, complete eds 22
445527 W39694 Hs 83286 ESTs, Weakly similar to S14747 sphmgomy 22
445280 AW055063 Hs 306088 v-crk avian sarcoma vims CT10 oncogene 22
420653 AI224532 Hs 88550 ESTs 22
419926 AW900992 Hs 93796 DKFZP586D2223 protein 22
447541 AK000288 Hs 18800 hypothetical protein FLJ20281 22
424408 AI754813 Hs 146428 collagen, type V, alpha 1 22
411893 R82845 Hs 273789 ESTs 22
428192 AA424051 Hs 304742 ESTs 22
435634 T82384 gb yc14f05 r1 Stratagene lung (937210) H 22
437637 AJ003029 Hs 65792 syntrophin, gamma 2 22
438018 AK001160 Hs 5999 hypothetical protein FLJ10298 22
446164 AW273539 Hs 288750 hypothetical protein FU23577 22
450232 BE300815 Hε 201326 ESTε 22
439699 AF086534 Hs 187561 ESTε, Moderately similarto ALULHUMAN A 22
402745 22
434008 AA740878 Hs 112982 ESTs 22
439492 AF086310 Hs 103159 ESTs 22
436853 BE328074 Hs 148661 ESTs 22
417648 R06552 gb yf09e12 r1 Soares fetal liver spleen 22
427690 AI253134 Hs 283410 ESTε 22
414217 AI309298 Hs 279898 Homo sapiens cDNA FLJ23165 fis, clone L 22
450229 R18717 Hε 8929 hypothetical protein FLJ 11362 22
400756 22
408447 AK002089 Hs 45080 Homo sapiens cDNA FLJ11227 fis, clone PL 22
403388 22
433643 AI821787 Hs 179586 ESTs 22
442078 AW268583 Hs 262629 ESTs 22
455685 BE066976 gb PM0-BT0340-211299-003-c12 BT0340Homo 22
432242 AW022715 Hs 162160 ESTs, Weakly similar to ALU4.HUMAN ALU S 22
439920 H05430 Hs 288433 neurotπmin 22
432436 AW300248 Hs 181693 ESTs 22
429493 AL134708 Hs 145998 ESTs 22
425555 AA359291 Hs 130767 Homo sapiens cDNA FU23553 fis, clone L 22
450101 AV649989 Hs 24385 Human hbc647 mRNA sequence 22 442757 AI739528 Hs 28345 ESTs 22
430212 AA469153 gb nc67f04 s1 NCI.CGAP.Pr1 Homo sapiens 22
437146 AA730977 gb nw55f05 s1 NCI_CGAP_Ew1 Homo sapiens 22
432101 AI918950 Hs 123642 EphA3 22
459644 22
453887 BE564037 Hs 36237 hypothetical protein 22
431170 AW971246 Hs 291022 ESTs 22
428062 AA420683 Hs 98321 hypothetical protein FLJ14103 22
443682 AI383061 Hs 47248 ESTs, Highly similar to similar to Cdc14 22
400441 M15530 Hs 99879 B-cell growth factor 1 (12kD) 22
453874 AW591783 Hs 36131 collagen, type XIV alpha 1 (undulin) 22
425810 AI923627 Hs 31903 ESTs 22
433037 NM 014158 Hs 279938 HSPC067 protein 22
407162 N63855 Hs 142634 zinc finger protein 22
441826 AW503603 Hs 129915 phosphotπesterase related 22
446901 AI347274 gb tc05d02 x1 NCI CGAP_Co16 Homo sapiens 22
454766 AW866497 gb QV4-SN0024-170400-176-e07 SN0024 Homo 22
414221 AW450979 gb UI-H-BI3 ala-a 12-0 UI s1 NCI_CGAP.Su 22
459608 AL119471 gb DKFZp761M141_r1 761 (synonym hamy2) 22
400639 22
406149 22
424027 AW337575 Hs 201591 ESTs 22
427531 AA405097 Hs 97957 ESTs 22
448353 BE407125 Hs 231510 ESTs 22
417669 T99898 gb ye68g01 r1 Soares fetal liver spleen 22
449650 AF055575 Hs 23838 calcium channel, voltage-dependent, L ty 22
452335 AW188944 Hs 61272 ESTs 22
419216 AU076718 Hs 164021 small inducible cytokine subfamily B (Cy 22
447748 AI422023 Hs 161338 ESTs 22
403534 22
410594 AW770778 Hs 281238 ESTs 22
438550 AW976002 Hs 258402 ESTs 22
439626 N22415 Hs 189080 ESTs 22
444540 A1693927 Hs 265165 ESTs 22
450024 AA005129 gb zh90h08 r1 Soares_fetal_lιver_spleen_ 22
450221 AA328102 Hs 24641 cytoskeleton assxiated protein 2 22
439443 AF086261 Hs 127892 ESTs 22
418824 AW751661 Hs 53542 choreoacanthocylosis gene, KIAA0986 prot 22
451273 NM 014811 Hs 26163 KIAA0649 gene product 22
430607 AW973521 Hs 247324 mitxhondπal ribosomal prote S14 22
432702 AW973953 Hs 293744 ESTs 22
414195 BE263293 Hs 89605 cholmergic rxeptor, nicotmic, alpha p 22
425570 AA359558 gb EST68590 Fetal lung II Homo sapiens c 22
414935 C15671 gb C15671 Clontxh human aorta polyA÷ mR 22
453153 N53893 Hs 24360 ESTs 22
430832 AI073913 Hs 100686 ESTs, Weakly similar to JE0350 Aπteπor 22
439867 AA847510 Hs 161292 ESTs 22
419780 AA713522 Hs 87752 ESTs 22
433420 AI674093 Hs 293961 ESTs, Moderately similar to putative DNA 22
434690 AI867679 Hs 148410 ESTs 22
436572 AA723274 Hs 279596 ESTs 22
447044 AF030107 Hs 17165 regulator of G-protein signalling 13 22
431688 AA513906 gb ng67c08 s1 NCI_CGAP_Lιp2 Homo sapiens 22
403133 22
414885 AA157531 Hs 269276 ESTs, Moderately similar to S65657 alpha 22
432111 AW972777 gb EST384871 MAGE resequences, MAGL Homo 22
410073 AW408163 Hs 58488 catenm (cadheππ-assxiated protein), a 22
448869 AI792798 Hs 12496 ESTε, Weakly similar to ALU4JHUMAN ALU S 22
429525 N92540 Hs 205353 xtonucleoside tπphosphate diphosphohyd 22
446565 D13757 Hs 311 phosphoπbosyl pyrophosphate amidotransf 22
422386 AF105374 Hs 115830 heparan sulfate (glucosamine) 3-O-sulfot 22
406687 M31126 Hs 272620 pregnancy spxific beta-1 -glycoprotein 9 22
403378 22
431369 BE184455 Hs 251754 sxretory leukxyte protease inhibitor ( 22
438580 AA811262 Hs 299202 ESTs 22
409191 AW818390 Hs 175613 homolog of Xenopus Claspin 22
412282 BE160188 gb QV1-HT0413-010200 059-g05 HT0413 Homo 22
411966 AA099113 Hs 118609 ESTs 22
443915 Z40763 Hs 135292 ESTs 22
427785 X81053 Hs 180828 collagen, type IV, alpha 4 22
446094 AK001760 Hs 13801 KIAA1685 protein 22
436486 AA742221 Hs 120633 ESTs 22
411139 AW819461 gb RC5-ST0293-061299-031-C03 ST0293 Homo 22
409070 AA063003 Hs 224560 ESTε 22
432713 AL118623 Hs 29494 PR01912 protein 22
419384 AA490866 Hs 39429 ESTε 22
418858 AW961605 Hs 21145 hypothetical protein RG083M052 22
408444 AW661839 Hs 253204 ESTs 22
432128 AA127221 Hs 117037 ESTs 22
418027 AB037807 Hs 83293 hypothetical protein 22
446060 Z42061 Hs 27004 ESTs 22
436196 AK001084 Hs 333498 Homo sapiens cDNA FLJ10222 fis, clone HE 22
411987 AA375975 Hs 183380 ESTs, Moderately similar to ALU8 HUMAN A 22 443401 AI394067 Hs 160159 ESTs 22
424665 AW368576 Hs 139851 caveolm 2 22
416143 A1955650 Hs 79033 glutaminyl peptide cyclotransferase (glu 22
426261 AW242243 Hs 168670 peroxisomal farnesylated protein 22
414564 AA164803 Hs 71994 ESTs, Weakly similar to I38022 hypotheti 22
427897 NM 017413 Hs 303084 apelm, peptide ligand for APJ receptor 2 2
419160 AA911342 Hs 35524 K1AA1559 protein 22
420111 AA255652 gbzs21h11 r1 NCI.CGAP.GCB1 Homo sapiens 22
442879 AF032922 Hs 8813 syntaxm binding protein 3 22
430486 BE062109 Hs 241551 chloride channel, calcium activated, fam 22
453823 AL137967 gb DKFZp761D2315 r1 761 (synonym hamy2) 22
432074 AA525248 Hs 149723 ESTs 22
431848 AI378857 Hs 126758 ESTs, Highly similar to AF175283 1 zinc 22
447072 D61594 Hs 17279 tyrosylprotein sulfotransferase 1 22
409723 AW885757 Hs 257862 ESTs 22
425627 AF019612 Hs 297007 membrane bound transcnption factor prot 22
435090 BE217923 Hs 149595 ESTs 22
449369 AA001256 Hs 27260 ESTs 22
425514 AF112345 Hs 158237 integπn, alpha 10 22
455821 BE143341 gb MR0 HT0162-191099 002-d04 HT0162 Homo 22
427224 AL135554 Hs 101937 sine xulis homeobox (Drosophila) homolo 22
432284 AA532807 Hs 105822 ESTs 22
403467 22
436032 AA150797 Hs 109276 latex protein 2.2
404356 22
434205 AF119861 Hs 283032 hypothetical protein PRO2015 22
405257 2 2
402103 22
456649 R74441 Hs 117176 poly(A) binding protein, nuclear 1 22
432985 T92363 Hs 178703 ESTs 2 2
417649 AW239285 Hs 82359 tumor necrosis factor rxeptor superfami 22
431277 AA501806 Hs 249965 ESTs 22
454056 AI368836 Hs 24808 ESTs, Weakly similar to I38022 hypotheti 22
401694 22
423531 AW752782 Hs 129750 hypothetical protein FLJ 10546 22
431364 AW971382 Hs 294016 ESTs, Moderately similar to B34087 hypot 2 2
445908 R13580 Hs 13436 Homo sapiens clone 24425 mRNA sequence 2 2
448390 AL035414 Hs 21068 hypothetical protein 22
449939 T86420 Hs 272139 ESTs 22
455678 BE066007 gb RC3-BT0319-120200 014-d09 BT0319 Homo 2 2
404555 22
418186 BE541042 Hs 23240 Homo sapiens cDNA FLJ21848 fis, clone H 22
419981 AA897581 Hs 128773 ESTs 22
449581 AI989517 Hs 181605 ESTs 22
419229 AI827237 Hs 282884 ESTs 22
403691 22
423728 AW891294 Hs 132136 solute camerfamily 4, sodium bicarbon 22
443479 AF027218 Hs 9443 zinc finger protein 202 22
425329 AI961644 Hs 145444 Homo sapienε cDNA FU11494 fis, clone HE 22
453345 AA302862 Hs 90063 neurocalcin delta 22
424335 AW021508 Hs 28170 ESTs 22
451072 AA013451 Hs 117929 ESTs 22
417845 AL117461 Hs 82719 Homo εapiens mRNA, cDNA DKFZp586F1822 (f 22
411571 AA122393 Hs 70811 hypothetical protein FLJ20516 2 2
438035 AA938198 Hs 146123 poly(A) polymerase gamma 22
432374 W68815 Hs 301885 Homo sapiens cDNA FU11346 fis, clone PL 22
400241 2 2
408908 BE296227 Hs 250822 senne/threon e kinase 15 2 2
409564 AA045857 Hs 54943 fracture callus 1 (rat) homolog 22
411151 AW866497 gb QV4-SN0024-170400-176 e07 SN0024 Homo 22
446009 AI989885 Hs 231926 ESTs 22
456855 AF035528 Hs 153863 MAD (mothers against dxapentaplegic, Dr 2 1
416441 BE407197 gb 601301552F1 NIH.MGC.21 Homo sapienε c 2 1
414891 R27124 Hs 268754 Homo εapienε cDNA FLJ11949 fiε, clone HE 2 1
430172 AA468591 Hs 161889 ESTs 21
422109 S73265 Hs 1473 gastnn-releasmg peptide 2 1
422985 AU076411 Hs 1602 dihydropyπmidme dehydrogenase 2 1
448552 AW973653 Hs 20104 hypothetical protein FLJ00052 21
422373 AK001843 Hs 115700 Homo sapiens cDNA FLJ23515 fis, clone L 2 1
450726 AW204600 Hs 250505 retinoic xid receptor, alpha 2 1
438379 N23018 Hs 171391 C-terminal binding protein 2 21
412608 AA247995 Hs 44898 Homo sapiens clone TCCCTA00151 mRNA sequ 2 1
451270 AW341392 Hs 235795 ESTε 2 1
412140 AA219691 Hs 73625 RAB6 interacting, kinesm like (rabkmes 21
415992 C05837 Hs 145807 hypothetical protein FLJ 13593 2 1
415533 T74009 Hs 268738 ESTε, Weakly similar to ALU7 HUMAN ALU S 2 1
437132 AL049353 Hε 297268 ESTs 2 1
415304 T66079 Hε 12799 ESTs 2 1
450152 AI138635 Hs 22968 Homo sapiens clone IMAGE 451939, mRNA se 21
421147 AW592167 Hs 293299 ESTε 21
421413 AI826128 Hs 57637 ESTε, Weakly similar to A4936459 protei 2 1
451750 AA280851 Hs 226930 ESTs 2 1
417924 AU077231 Hs 82932 cyclin D1 (PRAD1 parathyroid adenomatos 2 1 406945 K01383 Hs 173451 metallothionein 1A (functional) 2 1
452449 AW068658 Hs 20943 ESTε 2 1
436009 H57130 Hs 120925 ESTε 2 1
418637 T86737 Hε 193536 ESTs 21
420495 AI338247 Hs 98314 Homo sapiens mRNA, cDNA DKFZp586L0120 (f 2 1
449203 AI634578 Hs 282121 ESTs 2 1
437751 AA767373 Hs 35669 ESTs, Moderately similar to ALULHUMAN A 21
428412 AA428240 Hs 126083 ESTs 2 1
425707 AF115402 Hs 11713 E74-lιke fxtor 5 (ets domain transcript 2 1
441967 AA972742 Hs 209786 ESTs 21
403317 U02687 Hs 385 fms related tyrosine kinase 3 2 1
406018 2 1
410566 AA373210 Hs 43047 Homo sapiens cDNA FLJ13585 fis, clone PL 21
416747 AW876523 Hs 15929 hypothetical protein FLJ 12910 2 1
431229 AA496479 Hs 259929 ESTs 2 1
435148 A1918049 Hs 124961 ESTs 21
436349 AI445255 Hs 115315 ESTs 2 1
446895 AA166655 Hs 282803 ESTs 2 1
448582 AI538880 Hs 94812 ESTs 2 1
442762 AF035119 Hs 8700 deleted in liver cancer 1 2 1
442738 AW002370 Hs 131055 ESTs, Weakly similar to NPM.HUMAN NUCLEO 21
451874 AW963137 Hs 194233 ESTs, Moderately similar to ALULHUMAN A 2 1
448076 AJ133123 Hs 20196 adenylate cyclase 9 2 1
443484 AI091458 Hs 134559 ESTs 21
430686 NM 001942 Hs 2633 desmoglein 1 2 1
446100 AW967109 Hs 13804 hypothetical protein dJ4620232 2 1
407624 AW157431 Hs 248941 ESTs 21
435079 AA664192 gb ac05b03 s1 Stratagene lung (937210) H 2 1
428923 BE047698 Hs 188785 ESTs 2 1
422496 AA311301 Hs 278827 ESTs 21
413385 M34455 Hs 840 indoleamme pyrrole 2,3 dioxygenase 2 1
408418 AW963897 Hs 44743 KIAA1435 protein 2 1
446733 AA863360 Hs 26040 ESTs, Weakly similar to fatty acid omega 21
427434 BE538374 Hs 301732 hypothetical protein MGC5306 2 1
428822 W28418 Hs 30715 potassium voltage-gated channel, Isk-rel 2 1
459325 AW088369 Hs 282184 ESTs 2 1
416996 W91892 Hs 59609 ESTs 2 1
425638 NM 012337 Hs 158450 nasopharyngeal epithelium spxific prote 2 1
408000 L11690 Hs 620 bullous pemphigoid antigen 1 (230/240kD) 2 1
418894 W73921 Hε 50743 ESTs 2 1
424687 J05070 Hs 151738 matnx metalloproteinase 9 (gelat ase B 21
437378 AI198823 Hs 160473 ESTs 2 1
454100 AI693231 Hs 126043 chromosome 21 open reading frame 51 2 1
452786 R61362 Hs 106642 ESTs, Weakly similar to T09052 hypotheti 21
437311 AA370041 Hs 9456 SWI/SNF related, matnx assxiated, acti 2 1
400631 AF173937 Hs 109494 sxreted protein of unknown function 2 1
440028 AW473675 Hs 125843 ESTs, Weakly similar to T17227 hypotheti 21
426490 NM 001621 Hs 170087 aryl hydrocarbon rxeptor 2 1
424103 NM.001918 Hs 139410 dihydrolipoamide branched chain transacy 2 1
407995 AI094748 Hs 100134 hypothetical protein FU12787 21
449911 A1262106 Hs 12653 ESTs 2 1
449509 AA001615 Hε 84561 ESTs 2 1
452762 AW501435 Hs 278582 v-akt munne thymoma viral oncogene homo 21
422839 A1674784 Hs 298908 ESTs 2 1
435040 AI932350 Hs 152825 ESTs 2 1
401200 2 1
416248 H99169 Hs 23450 mitochondnal ribosomal protein S25 2 1
442262 BE170651 Hs 8700 deleted in liver cancer 1 2 1
449754 H00820 Hs 30977 ESTs, Weakly similar to B34087 hypotheti 2 1
453908 AW613920 Hs 282178 ESTs 2 1
446965 BE242873 Hs 16677 WD repeat domain 15 21
412798 AW998657 Hs 119120 E3 ubiquitin ligase SMURF1 2 1
416085 H18072 Hs 92576 ESTs 21
418378 AW962081 gb EST374154 MAGE resequences, MAGG Homo 21
455995 BE179408 gb IL3-HT0618-060500-125-B07 HT0618 Homo 2 1
422411 AW749443 Hs 22511 ESTs 2 1
410888 AW861207 gb RC1-CT0302-120200-013J04 CT0302 Homo 2 1
446893 AI610818 Hs 7110 ESTε 21
442992 A1914699 Hs 13297 ESTs 2 1
407021 U52077 gb Human maπnerl traπsposase gene, comp 21
436938 AW139680 Hs 161393 ESTs 2 1
433194 AB040883 Hs 83243 KIAA1450 protein 2 1
454790 AW820852 gb RC2-ST0301-120200 011412 ST0301 Homo 21
431130 NM.006103 Hs 2719 epididymis-specific, whey-acidic protein 2 1
434739 AA804487 Hs 144130 ESTs 2 1
406468 2 1
457023 AA001732 Hs 173233 hypothetical protein FLJ10970 2 1
416226 N55342 Hs 34372 ESTs 2 1
422306 BE044325 Hs 227280 U6 snRNA assxiated Sm like protein 2 1
432810 AA863400 Hs 23054 ESTs 21
412894 R09778 Hs 186510 i ESTs 21
430602 D13752 Hs 184927 cytxhrome P450, subfamily XIB (steroid 2 1
436981 AA740891 Hs 293316 I ESTs 2 1 452501 AB037791 Hs 29716 hypothetical protein FLJ10980 2 1
449838 AB020653 Hs 24024 KIAA0846 protein 2 1
447160 AA330310 Hs 24181 ESTs 2 1
422156 N34524 gb yy56d10 s1 Soares multiple.sclerosis. 2 1
440137 AA866199 Hs 171397 ESTs 2 1
423998 H29138 Hs 157113 coenzyme Q, 7 (rat yeast) homolog 21
436471 AA719813 Hs 117662 ESTs 2 1
414680 AA743331 Hs 272572 hemoglobin, alpha 2 2 1
426782 R14614 Hs 191254 ESTs 21
430027 AB023197 Hs 227743 KIAA0980 protein 2 1
411562 AL050201 Hs 70769 hypothetical protein DKFZp586E1923 2 1
413252 BE074910 gb RC5 BT0580 170300021-F12 BT0580 Homo 2 1
427115 AW972853 Hs 112237 ESTs 2 1
444610 AI174783 gb HA2501 Human fetal liver cDNA library 2 1
400451 2 1
435255 W87434 Hs 106015 ESTs, Moderately similar to ALULHUMAN A 2 1
450159 A1702416 Hs 200771 ESTs, Moderately similar to A Cham A T 2 1
418375 NM.003081 Hs 84389 εyπaptoεomal assxiated protein, 25kD 2 1
442835 A1021989 Hs 131903 ESTs 2 1
400196 2 1
415734 NM 014747 Hs 78748 KIAA0237 gene product 2 1
415189 L34657 Hs 78146 plateleueπdothelial cell adhesion molec 21
438940 AF075045 Hs 271609 ESTε 2 1
425349 AA425234 Hs 79886 nbose 5 phosphate isomerase A (ribose 5 2 1
448515 H68441 Hs 13528 hypothetical protein FLJ14054 21
410557 AA085803 Hs 192997 ESTs, Moderately similar to I78885 serin 2 1
442562 BE379584 Hs 34789 dolichyl diphosphooligosacchaπde protei 2 1
413488 BE144017 gb MR0 HT0165-191199004-d09 HT0165 Homo 21
419088 AI538323 Hs 52620 integπn, beta 8 2 1
447373 AI381922 Hs 158781 ESTs 2 1
457465 AW301344 Hs 122908 DNA replication factor 21
413918 AW015898 Hs 71245 ESTs 2 1
402820 2 1
424872 AA347923 gb EST54302 Fetal heart II Homo sapienε 21
428552 AW274560 Hs 129520 ESTε 2 1
435464 BE548300 Hs 192999 ESTs, Moderately similar to KIAA0961 pro 2 1
449008 AW578003 Hs 22826 tropomodulm 3 (ubiquitous) 2 1
420838 AW118210 Hs 5244 ESTs 2 1
428231 U17989 Hs 183105 nuclear autoantigen 2 1
434933 R91095 Hs 4276 KIAA1701 protein 2 1
444870 AI200621 Hs 148504 ESTs 2 1
425354 U62027 Hs 155935 complement component 3a rxeptor 1 2 1
429183 AB014604 Hs 197955 KIAA0704 protein 2 1
439155 H81076 Hs 269001 ESTs 21
442787 W93048 Hs 250723 hypothetical protein MGC2747 2 1
429864 AA460039 Hs 286 πbosomal protein L4 2 1
438563 AA810665 Hε 134746 ESTs, Weakly similar to A46010 X linked 21
437140 AA312799 Hs 283689 xtivator of CREM in testis 2 1
421991 NM 014918 Hs 110488 KIAA0990 protein 2 1
446534 AI307356 Hs 175225 ESTs 21
407881 AW072003 Hs 40968 heparan sulfate (glucosamine) 3 O-sulfot 2 1
444838 AV651680 Hs 208558 ESTs 2 1
402318 21
410878 AW809201 Hs 314248 ESTs, Weakly similarto ALU4.HUMAN ALU S 2 1
414494 AA768491 Hs 6783 hypothetical protein FLJ22724 2 1
421306 AA806207 Hs 125889 ESTs 2 1
427027 AI924294 Hs 173259 uncharxteπzed bone marrow protein BM03 2 1
429088 D61542 Hs 227716 KIAA0934 protein 2 1
429859 NM 007050 Hs 225952 protein tyrosine phosphatase, rxeptor t 2 1
428060 AA420616 Hε 249483 ESTs 2 1
419953 BE267154 Hs 125752 ESTs 2 1
443718 AI083580 Hs 221373 ESTs 2 1
444187 AW138466 Hs 151274 ESTs 21
428048 AA705745 gb zf41b11 s1 Soareε_fetal_heart_NbHH19W 2 1
420195 N44348 Hε 26243 Homo εapieπε cDNA FU11177 fiε, clone PL 2 1
417404 NM 007350 Hs 82101 pleckstπn homology-like domain, family 2 1
442833 AA328153 Hs 88201 ESTs, Weakly similar to A Cham A, Cryst 2 1
430335 D80007 Hs 239499 KIAA0185 protein 2 1
414618 AI204600 Hs 96978 hypothetical protein MGC10764 21
434029 AA621763 Hs 170434 Homo sapienε cDNA FLJ14242 fis, clone OV 2 1
410945 AW811552 gb QV2-ST0145-071299-017-h10 ST0145 Homo 2 1
421247 BE391727 Hs 102910 general transcnption factor HH, polype 2 1
433374 AI821409 Hs 332789 EST 2 1
445644 R77766 Hs 271593 ESTs, Moderately similar to A47582 B-cel 2 1
450271 AI693900 Hs 200920 ESTs 21
448084 AI467800 Hs 271000 ESTs, Weakly similar to I38022 hypotheti 2 1
407864 AF069291 Hs 40539 chromosome 8 open reading frame 1 2 1
430998 AF128847 Hs 204038 indolethylamine N methyltranεferase 2 1
435542 AA687376 Hs 269533 ESTs 2 1
443544 AI076315 Hs 16359 ESTs 2 1
421103 AI625835 Hs 27104 Homo sapiens mRNA, cDNA DKFZp667D226 (fr 2 1
405759 2 1
446242 N66336 Hs 7360 ESTs 21 457938 AI373638 Hs 133900 ESTs 2 1
433017 Y15067 Hs 279914 zinc finger protein 232 2 1
436729 BE621807 Hs 3337 transmembrane 4 superfamily member 1 2 1
432839 AA579465 Hs 45207 hypothetical protein KIAA1335 2 1
439224 AW471088 Hs 145950 ESTs, Highly similar to T08692 hypotheti 2 1
410976 R36207 Hs 25092 hypothetical protein MGC10744 2 1
454574 AW809109 gb MR4-ST0117-070100 027-a04 ST0117 Homo 2 1
411020 NM 006770 Hs 67726 macrophage receptor with collagenous str 2 1
452279 AA286844 Hs 61260 hypothetical protein FLJ13164 2 1
446891 AL036877 Hs 282878 ESTs 2 1
434294 AJ271379 Hs 76194 ribosomal protein S5 2 1
449057 AB037784 Hs 22941 KIAA1363 protein 2 1
432769 AA620814 Hs 144959 ESTs 2 1
441224 AU076964 Hs 7753 calumenm 2 1
407891 AA486620 Hs 41135 endomucin 2 2 1
429017 AA463605 Hs 66295 multi PDZ-doma containing protein 2 1
406817 AI936028 gb wo47a09 x1 NCI CGAP_Gas4 Homo sapiens 2 1
430566 AA481282 Hs 190149 ESTs 2 1
449208 AW263635 Hs 48643 ESTs 2 1
451397 AA017432 Hs 84529 ESTs, Weakly similar to Z202.HUMAN ZINC 2 1
452042 H38857 Hs 243901 Homo sapiens cDNA FLJ20738 fis, clone HE 2 1
444779 AH 92105 Hε 147170 ESTε 20
433672 BE281165 Hs 288038 TLS-associated seπne-arginine protein 1 20
415954 AA171850 Hs 42251 ESTε 20
420273 AI652864 Hs 197257 ESTε 20
411354 AW992424 Hs 288141 hypothetical protein MGC3156 20
422389 AF240635 Hs 115897 protocadhenn 12 20
446994 AV650435 Hs 16755 MBIP protein 20
417793 AW405434 Hs 82575 εmall nuclear πbonucleoprotein polypept 20
422654 AA314316 Hs 163725 ESTs 20
425999 AW513051 Hs 332981 ESTs, Weakly similar to I38022 hypotheti 20
405634 20
451562 H04150 Hs 107708 ESTs 20
431958 X63629 Hε 2877 cadhenn 3, type 1 , P-cadheπn (placenta 20
422095 AI868872 Hs 282804 hypothetical protein FLJ22704 20
442010 AI032680 Hs 132213 ESTs 20
442991 BE281238 Hs 8886 hypothetical protein FLJ20424 20
425312 AA354940 Hs 145958 ESTs 20
415191 AA190381 Hs 120810 ESTs 20
416406 D86961 Hs 79299 lipoma HMGIC fusion partner-like 2 20
425316 AA354977 Hs 191565 ESTs, Moderately similar to T14342 NSD1 20
413753 U17760 Hs 75517 laminin, beta 3 (nice (125kD), kalinin 20
452241 AL050204 Hs 28540 Homo sapiens mRNA, cDNA DKFZp586F1223 (f 20
433571 AA765256 Hs 135191 ESTs, Weakly similar to unnamed protein 20
417094 NM_006895 Hs 81182 histamine N methyltransferase 20
409190 AU076536 Hs 50984 sarcoma amplified sequence 20
413783 AA314337 Hs 301547 πbosomal protein S7 20
423867 AA331886 gb EST35757 Embryo, 8 week I Homo sapien 20
429418 AI381028 Hs 118769 ESTs 20
445829 AI452457 Hs 145526 ESTs 20
452366 AK000464 Hs 29276 hypothetical protein FLJ20457 20
425704 U78293 Hs 159264 Human clone 23948 mRNA sequence 20
446593 W79572 Hs 13277 hypothetical protein FLJ22054 20
400462 20
422003 AA361760 Hs 296326 ESTs 20
444585 AW170015 Hs 6594 ESTs 20
444898 AI201548 Hs 308338 ESTs 20
403525 20
443031 AW134696 Hs 49418 ESTs 20
430818 AI311928 gb qo89h04 x1 NCI_CGAP_Kιd5 Homo sapiens 20
423690 AA329648 Hs 23804 ESTs, Weakly similar to PN0099 son3 prot 20
440941 BE268362 Hs 7535 COBW-like protein 20
409627 AW997628 Hs 313637 ESTs 20
433258 AI806626 Hs 207300 ESTε, Weakly similarto ALUB.HUMAN mi 20
412863 AA121673 Hs 59757 zinc finger protein 281 20
436476 AA326108 Hs 33829 bHLH protein DEC2 20
430259 BE550182 Hs 127826 RalGEF-like protein 3, mouse homolog 20
417280 AW173116 Hs 262206 ESTs 20
423528 AB011137 Hs 300938 KIAA0565 gene product 20
424800 AL035588 Hs 153203 MyoD family inhibitor 20
446019 AI362520 Hs 279789 histone dexetylase 3 20
435472 AW972330 Hs 283022 triggering rxeptor expreεεed on myeloid 20
424882 AI379461 Hs 153636 far upstream element (FUSE) binding prot 20
430473 AW130690 Hs 59962 ESTs 20
431363 M86528 Hs 266902 neurotrophin 5 (neurotrophin 4/5) 20
438118 AW753311 Hs 259415 ESTs 20
400859 20
405829 20
415258 AW752247 Hs 293853 ESTs 20
420314 H81671 Hs 320921 ESTs, Weakly similar to T22688 hypotheti 20
437733 AI792574 Hs 122876 ESTs 20
452019 AL157503 Hs 27552 Homo sapiens mRNA, cDNA DKFZp586N2424 (f 20
453118 AW195849 Hs 252757 ESTs 20 430706 NM 003540 Hs 247816 H4 histone family, member C 20
420568 F09247 Hs 247735 protocadhenn alpha 10 20
452759 AW590773 Hs 258996 ESTs 20
408496 A1683802 Hs 136182 ESTs 20
420674 NM 000055 Hs 1327 butyrylcholinesterase 20
410358 AW975168 Hs 13337 ESTs, Weakly similar to unnamed protein 20
450086 AW016343 Hs 233301 ESTs 20
410853 H04588 Hs 30469 ESTs 20
438607 AW080237 Hs 252884 ESTs 20
422232 D43945 Hs 113274 transcnption factor EC 20
432801 NM.016260 Hs 278963 zinc finger DNA binding protein Helios 20
402490 20
446551 A1308176 Hs 65636 ESTs 20
438315 R56795 Hs 82419 ESTs 20
445261 T79759 Hs 282939 ESTs, Weakly similar to I38022 hypotheti 20
401986 20
420335 AA258771 Hs 43616 Homo sapiens mRNA for FLJ00029 protein, 20
424698 AA164366 Hs 151973 hypothetical protein FLJ23511 20
435413 AI267476 Hs 46669 ESTs 20
458175 AW296024 Hs 150434 ESTs 20
458433 AL135352 Hs 255883 ESTs, Weakly similar to 138022 hypotheti 20
417494 AI369494 Hs 222137 ESTs 20
416045 H15990 Hs 31403 ESTs 20
424181 AL039482 Hs 142517 Homo sapiens mRNA, cDNA DKFZp434P0810 (f 20
445873 AA250970 Hs 251946 poly(A)-bιndιng protein, cytoplasmic 1-1 20
411578 AW238524 gb xp27c05 x1 NCI CGAP HN10 Homo sapienε 20
453116 AI276680 Hs 146086 ESTs 20
425692 D90041 Hs 155956 N-acetyltransferase 1 (arylamine N-xety 20
435608 AW183971 Hs 250896 ESTs 20
402102 20
458308 AI828155 Hs 211055 ESTs 20
438177 BE327015 Hs 281391 ESTs 20
415205 H71616 Hs 135233 ESTs 20
427244 AA402400 Hs 178045 ESTs 20
441384 AA447849 Hs 288660 Homo εapiens cDNA FLJ22182 fis, clone H 20
438979 AW976218 Hs 32565 ESTs 20
400285 20
405966 20
407407 AF050198 gb Homo sapiens putative mitochondnal s 20
427739 AW196755 Hs 98105 NYD-SP14 protein 20
433584 AW295399 gb UI-H-BI2-ahv-h-03-0-UI ε1 NCI.CGAP.Su 20
448956 AK001674 Hs 22630 cofactor required for Sp1 transcπptiona 20
439474 AI824060 Hs 211501 ESTs 20
421755 AW169454 Hs 207422 ESTs, Weakly similar to S71949 metallopr 20
454566 AW807605 gb MR4-ST0098-120100-001-b06 ST0098 Homo 20
418836 AI655499 Hs 161712 ESTs 20
453108 A1311457 Hs 99472 ESTs 20
447101 N72185 Hs 44189 ESTs 20
408873 AL046017 Hs 182278 calmodulin 2 (phosphorylase kmase, delt 20
426226 AA769045 gb oa80h07 s1 NCI_CGAP_GCB1 Homo sapiens 20
401157 20
407721 Y12735 Hs 38018 dual-specιficιty tyrosιne-(Y)-phosphoryl 20
425646 AW157044 Hs 158512 cyclm-dependent kinase-like 2 (CDC2-rel 20
408964 AF201468 Hs 49349 beta εite APP-cleaving enzyme 20
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet-x 20
402855 20
443644 AI080491 Hs 93270 ESTs, Moderately similar to S65657 alpha 20
445672 AI907438 Hs 282862 ESTs 20
432343 NM 002960 Hs 2961 S100 calcium-binding protein A3 20
411941 AW876909 Hs 25201 ESTs, Weakly similar to FAT DROME CADHER 20
430664 AW969834 Hs 303303 ESTs 20
402812 20
457434 AW628192 Hs 18851 hypothetical protein FLJ 10875 20
448133 AA723157 Hε 73769 folate rxeptor 1 (adult) 20
402048 20
423347 AI660412 Hs 234557 ESTs 20
423957 AW978309 Hs 136235 Homo sapiens cDNA FU13542 fis, clone PL 20
433347 AF023130 gb Homo sapienε Ras-GRF2 mRNA, partial c 20
437373 H67505 Hs 191979 KIAA1733 protein 20
439217 AF086041 Hs 42975 ESTs 20
446609 BE395090 Hs 15535 Homo sapiens clone 24582 mRNA sequence 20
TABLE 3B List of xcession numbers for pπmekeyε Ixking unigenelD'ε for Table 3A Forsuch such probeset is listed a gene cluster number from which the oligonucleotides were designed Gene clusters were compiled using sequences derived from Genbank ESTs and mRNAs These sequences were clustered based on sequence similaπty using Clusteπng and Alignment Tools (DoubleTwist, Oakland California) Genbank acceεsion numbers for sequences compπsing each cluster are listed in the "Accession" column
Pkey Unique Eos probeset identifier number CAT number Gene cluster number
Accession Genbank accession numbers
Pkey CAT number Accession 408690 1074901 AW864542 AA056567 AW882724
409029 10954221 BE087807 AW301579
409073 109851 1 AA063458 AA063018 AI444822
409519 1137221 AA075368 AA075369
409695 1148761 AA296961 AA296889 AA076945 AA077528 AA077497
410008 1168121 AA079552 BE142525 BE142527
410615 12122031 AW772721 AW873372H89212
410672 12148821 AW794600 AW794730
410784 12210051 AW803201 BE079700 BE062940
410785 12210551 AW803341 AW803265 AW803403 AW803466 AW803402 AW803413 AW803268 AW803396 AW803334 AW803355
410888 12259551 AW861207 AW809508
410901 1226077.1 AW810001 AW810092 AW810170 AW809884 AW809664 AW810353 AW810428 AW810209 AW810429 AW810154 AW810168 AW809786
AW810006 AW809672 AW809694 AW810552 AW810345 AW810432 AW809960
410934 12272401 AW811114AW811095 AW811087 AW811124 AW811054AW811094 AW811157
410945 1227561 1 AW811552 AW811470AW811523AW811482 AW811514 AW811456 AW811525
410999 12288091 AW813004 AW812962 AW812961
411004 12289751 AW813242 BE146089 AW813195 AW813173 AW813206 BE145953 BE146212 AW813196 AW854582 AW813241 BE061582
411018 1229132.1 AW813428 AW813444 AW813367 AW813368 AW813429 AW813424
411139 1233781 1 AW819461 AW819478AW819479 AW819559 AW819505
411151 12340221 AW866497 AW819775 AW819868 AW866602 AW866561
411479 1247077.1 AW848047 AW848202 AW848631 AW848142 AW848702 AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069
AW848905 AW848214
411514 12486381 AW850178 AW850233 AW850445 AW850446
411578 1250131 AW238524 AA094059 R59022
411745 12561601 AW867826 AW859896
411880 12631101 AW872477 BE088101 T05990
411905 1265181 1 BE265067 BE264978 AW875420
412167 12806051 AW897230 AW897252 AW897244 AW897231 AW897263
412209 12836101 AW901456AW901450AW901441 '
412248 12850001 BE176480 AW903298 AW903313
412282 12876791 BE160188 AW935785 BE160401 BE160319 BE160313 BE160395
412303 12881301 AW936336 AW936339
412566 13064691 AW962574 BE073261
412877 13339531 BE011168 BE006371 BE011172 BE011313 BE011166
412879 13342721 BE092219 BE092361 BE006789
413087 13487201 BE064655 BE153953
413136 1350379.1 BE066941 BE066911 BE066979 BE066929 BE066925
413252 13558771 BE074910 BE074913 BE074911 BE074903 BE074892 BE074935
413382 13659541 BE090689 BE090685 BE090697 BE090680 BE090691 BE090696 BE090698 BE090686
413488 13732341 BE144017 BE185527 BE144023
413499 13739101 BE144884 H97942
413618 13803841 BE154078 BE154006 BE153891 BE153523 BE153983
413638 13812381 H71252 BE154668 BE154642
413642 13813861 BE154837 BE154879 BE154850 BE154877 BE154835 BE154849 BE154902 BE154905 BE154867 BE154901 BE154904 BE154899
413875 13967661 BE176776 H85072
414109 14173071 BE250744 BE294770
414221 142696.1 AW450979 AA136653 AA136656 AW419381 AA984358 AA492073 BE168945 AA809054 AW238038 BE011212 BE011359 BE011367 BE011368
BE011362 BE011215 BE011365 BE011363
414605 1465790 -1 BE390440
414935 15091571 C15671 C15333 C15833 D81433 C14657 C14811
415236 15310801 R41400 H06659 Z38637 F02023T16516
415635 15408531 F13168 R21289T77628
415747 1551891 AA381209 AA381245 AA167683
415980 15642181 R52414 R61681 H12009 T74429
416288 15859831 H51299 H44619 H46391 R86024 H51892T72744
416337 15892991 H48713 H83057 H48694 H65247
416441 1594801 BE407197AA182474AA180369 BE275628BE276131
416548 1600181 1 H62953 N76608 N72413
416624 16046941 H69044T47567 H75691 T50292
416871 16267611 H98716 N90792 24283
416913 163001.1 AW934714 BE161007 BE162500 AW749902 AW749864 BE162498 BE161005 AA190449 AW513465 BE161006 BE162499
416972 1636681 BE019670 AA191284 AA191255
417561 1687472 AW974345 BE145400 T97088 AA639076
417648 16910701 R06552T98985 R08656
417669 16921571 T99898 T92080 T91447 R07806 R07779
417859 17037241 T26453 Z44226 R20425
418378 1746561 AW962081 AA218925 AA354237
418636 177402.1 AW749855 AA225995 AW750208 AW750206
419546 1857661 AA244199 AA244272 H57440
419637 1866391 W27493 AA248063 AA249685 AA429679
419807 188252.1 R77402 AA262462 AA250988 R06794
420111 1907551 AA255652 AA280911 AW967920 AA262684
420621 1951131 AA278808 BE082076 BE081812 BE081581
420637 195241 1 AW976153 AA278945 AA747691
421065 1989361 AA329711 AA287436AA283148
422063 210852.1 BE156476 BE156473 BE156474 BE156475 AA302839
422156 212379.1 N34524 AA305071 AW954803 AA502335 AI433430 AI203597 AW026670 AW265323 AW850787 AA317554 AW993643 AW835572 AW385512
AI334966 W32951 H62656 H53902 R88904 AW835732
422342 2154981 AA309272 AA309312 AW961837
422429 2164691 AA310527 AW962295 Z44865 H06641
422977 2234101 AA631498 AI017191 AA491211 AA761823 AA714555 AA768099 AA808286 AI934069 AA570223 AA574389 AA582438 AI745346 AW964510
AA319642 AW853758 H56414
423121 225175 1 AW864848 AA322213 AA322209 AW961624 423377 227691 AL049377 AL079930 AL047223 AW885968 AA385235
423532 229362.1 BE090503 BE090490 BE090483 BE090501 BE090500 BE090365 BE0905058E090509 BE090499 BE090502 BE090504 BE090497 AA327285
423735 2314981 AA330259 AA661806 AA502431 AW974633 AA649496
423841 2325071 AW753967 AA370795 AA331630 AW962550
423867 232732.1 AA331886 AW962659 AW962655 T89841
424872 2445051 AA347923 AA347928 AW961769
425201 2479331 AA352111 AW962247 AA429695
425497 2524991 AA524596 AA358494 AA513507
425570 2532481 AA359558 AA359819 AW963122
426226 2629181 AA769045 AA372590 AW963633
426497 268121 1 AA379913 AA379981 AW963523
426603 2698251 AA382291 AA994657
427551 2801631 T96203 AA405343 T96121
428048 2863941 AA705745 AA420850 AA420433
428679 2940491 AA431765 AA432015
430212 3144371 AA469153 A1718503 AA469225
430818 3242391 AI311928 AA936030 T51931 AA609816 AA487195 AA664207
430844 324570.1 T94960 AA487679 T95013
430933 3257571 AW863635 BE179901 BE179402AW863789 AA489179 BE010747 BE010748
431071 3275501 AA491379 H86020 AW969148
431169 3287991 AW971240 AA493843 AA493723
431322 3315431 AW970622 AA503009 AA502998 AA502989 AA502805 T92188
431595 3355121 AA508196 BE142920 AI280311 AI205616 D61709
431688 3366091 AA513906 AA847734 AI357044
432111 3416181 AW972777 AA526795 AA526305
432189 3428191 AA527841 AI810608 AI620190 AA635266
432222 343347.1 AI204995 AW827539 AW969908 AW440776 AA528756
432779 3540241 AW979241 AA565006 AA847102
432803 354267.1 AA565398 AW894072 H97930
432869 3554751 AW974094 AA569074 AA602574
433347 363881 AF023130AF181250 AA984703 AA694303 AA351792
433492 3679341 AW605849 AW262898 N41060 AA594852
433584 3704001 AW295399 AW207772 AW300641 AW070290 BE348854 AW170383 AA600968 AA778832
433644 3719191 AW342028 AA641080 AA603282
433687 373061 1 AA743991 AA604852 AW272737
434138 380572J AA625804AW418787 AW074833 AI675642 AI393368
434374 384889 AA631439 AI086355 AI082577
434613 3895501 AI821826 AA640657 AA658836 AA650055 AI821079
434638 389901 H50758AF147434 H50666
434950 396061 1 AW974892AA654375
434995 3972101 AW974995 AI821880 AI821932 AI791196 AA659617 AI821137 AA658925
435079 3997831 AA664192 H60250 T71388
435463 4065821 AA682507 AW851124
435634 4092391 T82384 R05307AA693714
436532 421802.1 AA721522 AW975443 T93070
437146 43371.1 AA730977 AI261584 AA334473 Z43283AW875861 AW938044 BE150701 AW936262AA306862 BE565575 BE567380 AA728920 AA167612
AI239729 AI251752 AA485791 BE568425 AW962958
438005 4475531 BE151746 BE336853 D63271 T94955 AA774994
438458 4578371 AW975186 AA807807 D29548
438909 466841 AF085839 R69137 AW188788 R69254
438993 4676511 AA828995 AA834879 AI926361
440320 4919301 AA878294 N67538 AI474541
440674 49997.1 BE561546 Z25124 AI307139 Z28800
443613 575391 1 AI079356W23287
443657 5766851 R14973 R14967 A1081006
444314 6006671 AI140497 AW749625 AW749626 AW749644
444610 6122571 AI174783 R83569 R12271
444910 624951 1 AI201849 BE069007 AW946544
446096 6619591 AI276454AI633717 AI275116
446901 6978091 AI347274AW844024
447197 7116231 R36075 AI366546 R36167
448404 7615151 BE089973 AI498612 AW805032
449540 809452 AA001713 H63836
450024 822961 AA005129 AA679084 AA694399
450458 835861 AA009926 BE149301
450522 8372641 AI698839 A1909260 A1909259
451024 855651 AA442176 AA259181
451487 87131 1 AA018072 N46370 R84847
452453 9183001 A1902519 AI902518 AI902516
452542 9214101 AW812256 AW812257AI906423 AI906422
453823 9825261 AL1379S7 BE064160 BE064186
453901 9864141 BE065902 AW749032 AW003637
454190 10499961 AW177821 AW177896 AW177867
454193 10502561 BE141183 AW178167 AW178162 AW178166 AW178172 AW845893 AW178159 AW178222 AW178213 AW178215 AW178090 AW178091
AW178161 AW178207 AW178210 AW178214 AW178212 BE140918 BE140917 AW178135 AW178205 AW178209 AW178223 AW178220
AW178206 AW178203 AW178165 AW178168 AW178160 AW178136 AW845878 AW178131 AW178138 AW178105 AW845894 AW178129
AW845810 AW845828 AW178216 AW178112 AW178211 AW178224 BE140915 AW178221 AW178130 AW178134 AW178096 AW178108
AW178133 AW178164AW178218 AW178171 AW178157 AW178158 AW178103 BE141189 AW178170AW845816 BE141586 AW178156
AW178104 AW178163 AW178093 AW178208 AW178137 AW178140 AW178219 BE141592 AW845901 BE141580 AW178155 BE141598 BE140957
454352 1129667.1 AW389668 AW389657 AW609198 AW389649 454359 1130674.1 N71277AW390764 454389 115682.1 AW752571 AW847602 AA077979 454403 1170435.1 BE065985 BE065944 BE066008 BE066083 BE066093 454455 12069651 AW752710 BE180336 BE180186 454566 1224432.1 AW807605 AW807690 AW807839 AW807752 AW807673 AW807667 AW807955 AW807760 AW807615 AW807898 AW807849 AW807821
AW807832 AW807842 AW807827 AW807822 AW807829 AW807830 AW807825 AW807603 AW807612 AW807908 AW807595 AW807617
AW807678 AW807687 AW807918 AW807921 AW807596 AW807602 AW807688 AW807609 AW807684 AW807770 AW807593 AW807754
AW807679 AW807957 AW807683 AW807763 AW807902 AW807840 AW807819 AW807836 AW807769 AW807685 AW807847 AW807674
AW807686 AW807670 AW807917 AW807677 AW807680 AW807900 AW807669 AW807952 AW807907 AW807846 AW807756
AW807835 AW807608 AW807753 AW807601 AW807956
454574 12256361 AW809109 AW809112 AW809122 AW809126 AW809128 AW809133 AW809131 AW809113 AW809111 AW809132
454600 1226077.1 AW810001 AW810092 AW810170 AW809884 AW809664 AW810353 AW810428 AW810209 AW810429 AW810154 AW810168 AW809786
AW810006 AW809672 AW809694 AW810552 AW810345 AW810432 AW809960
454678 12289151 AW813089W28102
454693 12291321 AW813428 AW813444 AW813367 AW813368 AW813429 AW813424
454714 12304931 AW815098 BE154843 BE154831
454766 12340221 AW866497 AW819775 AW819868 AW866602 AW866561
454784 12346301 AW820626 AW820621 AW820608
454790 12347521 AW820852 AW820773 AW821088
454836 12365091 AW833711 AW833620 AW833699
454962 12467501 AW847645 AW847791 AW854083 AW853945
455047 12505361 AW852530 AW852527 AW852526
455092 12529711 BE152428 AW855572 AW855607
455100 12533341 BE160198 AW935898 T11520 AW935930 AW856073 AW861034
455107 12538741 BE154113 AW856797 AW856847 AW861128 AW856817
455114 12541061 AW857121 AW857123AW861238
455170 12569061 AW860972 AW862598 AW862599 AW860988 AW860983 AW860898 AW860925 AW860922 AW860986 AW860984 AW860989
455201 12597481 AW947884 AW947918 AW947888 AW947883 AW947897 AW947910 AW947905 AW864751 AW947878
455226 12625341 AW902103 AW869012 AW869139
455252 12662221 AW876627 AW876630 AW876631 AW876625
455286 12735761 BE144384 AW887474 AW887403 BE144386
455310 12781581 AW893961 AW893998 AW894034 AW894019
455431 12898541 AW938484 BE001245 BE001190
455488 129372 -1 AA102322
455511 13212291 BE144762 AW979091
455512 13214431 AW983608 AW983628 AW983610 AW983688 AW983601 AW983645 AW983607 AW983640 AW983625 AW983612 AW983642 AW983687
AW983602 AW983624 AW983634 AW983637 AW983632 AW983617 AW983635 AW983630 AW983636 AW983639 AW983616 AW983689
AW983641 AW983621 AW983603 AW983609 AW983623 AW983644 AW983618 AW983615 AW983611 AW983604 AW983686 AW983622
AW983619 AW983633 AW983589 AW983605 AW983626 AW983643 AW983631 AW983627 AW983613 AW983614 AW983685 AW983593
AW983590 AW983594 AW983620 AW983638 AW983592 AW983588
455571 13318851 BE003714 BE003721 BE003720 BE003716
455631 13475451 BE063031 BE063002 BE063008 BE063024 BE063040 BE063006 BE063072
455678 13497161 BE066007 BE066017 BE066074
455685 13503931 BE066976 BE066928 BE066927
455807 13709141 BE141140 BE141139 BE141105 BE141143 BE141127 BE141202 BE141108
455821 13727141 BE143341 BE143344 BE143378 BE143358
455866 13771191 BE149024 BE149056 BE152826 BE149025 BE149057 BE152819 BE149030 BE149062 BE149023 BE149055
455992 1398552.1 BE179015 BE178965 BE179010 BE179002 BE178961 BE179005 BE178964 BE179012 BE179011 BE178963 BE178997
455995 13989031 BE179408 BE179798 BE179980
456034 142696.Ϊ AW450979 AA136653 AA136656 AW419381 AA984358 AA492073 BE168945 AA809054 AW238038 BE011212 BE011359 BE011367 BE011368
BE011362 BE011215 BE011365 BE011363
458804 75803.1 AL157625 72696 BE622492
458861 7980851 AI630223 A1630470
459160 920051 1 AI904723 AI904725 AI904729 AI904722 AI904758 AI904736
459201 9258831 AW391177 W45021 '
459267 9666051 AJ003631 AJ003650AJ003651
TABLE 29C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400451 8113550 Minus 82189-82320
400462 9929659 Minus 197610-197785
400608 9887666 Minus 96756-97558
400639 9887597 Plus 23150-23580
400641 8117693 Plus 4786-4992
400756 8119084 Minus 38734-38857
400859 9757499 Minus 91888-92018,98131-98294,99474-99570
400880 9931121 Plus 29235-29336,36363-36580
400889 9958234 Minus 169782-170036
400983 8081198 Plus 107903-108832
401045 8117619 Plus 90044-90184,91111-91345
401049 7232177 Plus 149157-150692
401078 3687273 Plus 105052-105171
401094 9965511 Plus 137130-137302,139283-139506
401103 8568122 Minus 98330-98449
401157 9438289 Minus 114133-114247,114567-114645
401189 9690246 Minus 90815-90929 401200 9743387 Minus 111586-111806,114791-114916,115419-115583,116351-116446,116847-116907,122853-123067,124982--
401213 9858408 Plus 98243-98380,98489-98619
401254 9796309 Plus 152209-152383
401323 9212516 Plus 213509-214450
401335 9884881 Plus 15736-16352
401497 7381770 Plus 92607-92813
401517 7677912 Plus 29278-29770
401526 7770561 Plus 91570-93177
401575 7229804 Minus 76253-76364
401694 3540172 Minus 64056 64168
401793 7263888 Minus 102945-103083
401862 7770606 Minus 55839-55993,59145-59293
401878 8099802 Minus 162268-162474,163089-163195
401986 4406829 Minus 31137-31293
402046 8072415 Plus 166394-166556,168167-168395
402048 8072512 Plus 43936-44078
402102 8117771 Minus 174566-174740
402103 7249203 Plus 14453-15414
402230 9966312 Minus 29782-29932
402318 7582559 Minus 12843-13403
402490 9797648 Plus 149982-150929
402745 9212200 Minus 76516-76690
402800 6010175 Plus 43921-44049,46181-46273
402812 6010110 Plus 25026-25091,25844-25920
402820 6456853 Minus 82274-82443
402855 9662953 Minus 59763-59909
403133 7331427 Plus 38314-38634
403271 7230852 Plus 134283-134485
403277 8072597 Minus 27494-27642
403310 8139936 Minus 183883-184026
403329 8516120 Plus 96450-96598
403356 8569930 Plus 92839-93036
403378 9438244 Minus 44264-44443
403388 9438331 Plus 112733-113001,114599-114735
403467 9829556 Minus 73431-73602
403515 7656757 Minus 173358-179553
403525 7960440 Plus 152431-153243
403534 8076917 Minus 46652-47332
403568 8101145 Minus 85509-85658
403574 8101156 Plus 5542-6176
403637 8671936 Minus 142647-142771,145531-145762
403677 7331517 Minus 55008-55083,62860-63051
403691 7387384 Minus 88280-88463
403760 7712202 Minus 45910-46260,47563-47824
403776 7770611 Minus 1414-1513,1624-1756
403895 7381715 Minus 3502-4002,4070-4308
403937 7711761 Minus 12609-12773
404043 9558573 Plus 29042-29135,46597-46699
404097 7770701 Plus 55512-55781
404200 6010176 Minus 7066-7210
404249 8655533 Plus 64270-64633
404274 9885189 Plus 104127-104318
404285 2326514 Plus 32282-32416
404288 2769644 Plus 3512-3691
404356 7630858 Minus 126433-126623
404443 7579073 Minus 87198-87441
404476 8080699 Plus 101841-102043
404488 8113286 Minus 64835-64994
404513 8151941 Minus 112837-113339
404548 8570305 Minus 83896-84162
404555 7243881 Minus 63963-64157
404561 9795980 Minus 69039-70100
404588 6456726 Minus 40059-40210
404593 9944086 Minus 74922-75788
404599 8705107 Plus 110443-110733
404860 8979555 Plus 65852-66081
404916 7341826 Plus 91057-91188
404957 7407927 Plus 147512-148011
405041 7547195 Plus 121230-121714
405059 7656683 Plus 349-822
405090 8072525 Minus 38552-39202
405257 7329310 Plus 73121-73273
405336 6094635 Plus 33267-33563
405472 8439781 Plus 106297-106447,108462-108596
405494 8050952 Minus 70284-70518
405547 1054740 Plus 124361-124520,124914-125050
405621 5523811 Plus 59362-59607
405634 5306288 Plus 17856-17957,18302-18412,18837-18927,22790-22989
405654 4895155 Minus 53624-53759
405692 4314424 Plus 61379-62562
405759 3288022 Minus 18283-18399
405829 7109593 Minus 15628-16127
405848 7651809 Minuε 28135-28244 405966 8247788 Minuε 51762-51978
405970 8247789 Minuε 45795-46295
406018 6758904 Minuε 37795-38168
406091 9123919 Minus 197370 197935
406092 9123919 Plus 251370 251797,252168 252882
406149 7144791 Minuε 44464-45164
406195 7289992 Minuε 36293-36827
406333 9213235 Plus 64689-64798
406468 9795553 Plus 4373 4616,8870 9046,11366 11509 11625-11880
406506 7711374 Minus 6843 8077
406554 7711566 Plus 106956 107121
406603 8272659 Minus 39506-39694
TABLE 30A ABOUT 1840 GENES UP REGULATED IN IDIOPATHIC PULMONARY FIBROSIS (IPF) COMPARED TO HYPERSENSITIVITY PNEUMONITIS (HP)
Table 30A lists about 1840 genes that are up regulated in idiopathic pulmonary fibrosis (IPF) sampleε as compared with hypersensitivity pneumonitis (HP) samples These were selxted from about 59680 probesets on an Affymetπx/Eos Hu03 Gene Chip array such that the ratio of "average" idiopathic pulmonary fibroεis sample expression level to "average" hypersensitivity pneumonitis sample expression was greater than or equal to about 20 The "average" idiopathic pulmonary fibrosis level was set to the 90* percentile amongst idiopathic pulmonary fibrosis samples The "average" hypersensitivity pneumonitis level was set to the 90* percentile amongst hypersensitivity pneumonitis samples
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of IPF (idiopathic pulmonary fibrosis) to HP (hypersensitivity pneumonitis)
Pkey ExAccn Unigene ID Unigene Title R1
450478 AW451709 Hs 271200 ESTs 20 2
432365 AK001106 Hs 274419 hypothetical protein FLJ10244 11 9
405654 11 8
440209 H05049 Hs 22269 neurexm 3 108
407811 AW190802 Hs 40098 cysteine knot superfamily 1, BMP antagon 104
439606 W79123 Hs 58561 G protein-coupled rxeptor 87 103
425259 AL049280 Hs 155397 Homo sapiens mRNA, cDNA DKFZp564K143 (fr 102
426230 AA367019 Hs 241395 protease, senne 1 (trypsin 1) 95
416653 AA768553 Hs 74170 metallothioπein 1E (functional) 93
420481 U50525 Hs 98201 Human BRCA2 region, mRNA sequence CG029 92
403574 9 1
415817 U88967 Hs 78867 protein tyrasine phosphatase, receptor t 88
419519 AI198719 Hs 176376 ESTs 82
435256 AF193766 Hs 13872 cytokine like pratem Cl 7 81
423017 AW178761 Hs 227948 serine (or cysteine) proteinase inhibito 81
429629 BE501732 Hs 30622 Homo sapiens cDNA FLJ13010 fis, clone NT 80
405443 78
428766 AA477989 Hs 98800 ESTs 77
441802 AA968636 Hs 127877 ESTs 76
453649 Y07494 Hs 34114 ATPase, Na+/K+ transporting, alpha 2 (+) 75
447410 AI470235 Hs 172698 EST 72
442353 BE379594 Hs 49136 ESTs, Moderately similar to ALU7_HUMAN A 72
405494 69
442377 AA993807 Hs 167367 ESTs 69
409928 AL137163 Hs 57549 hypothetical protein dJ473B4 68
420407 AA814732 Hs 145010 lipopolysaccaπde spxific response 5-lι 68
415236 R41400 gb yf94b12 s1 Soareε infant brain 1NIB H 68
451562 H04150 Hs 107708 ESTs 68
403310 67
445189 AI936450 Hs 147482 ESTs 67
409632 W74001 Hs 55279 seπne (orcyεte e) proteinase inhibito 67
439780 AL109688 gb Homo sapiens mRNA full length insert 66
402076 66
415025 AW207091 Hs 72307 ESTs 65
406690 M29540 Hs 220529 carcmoembryonie antigen related cell ad 65
438557 AW364104 Hs 143509 hypothetical protein FLJ21924 65
428042 AA419529 Hs 76391 myxovirus (influenza) resiεtance 1, homo 64
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial 64
409545 BE296182 Hs 19002 hypothetical protein MGC4675 64
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontin, 64
411966 AA099113 Hs 118609 ESTε 64
440274 R24595 Hs 7122 εcrapie reεponsive protein 1 63
442879 AF032922 Hs 8813 syntaxm binding protein 3 63
419236 AA330447 Hs 135159 Homo sapiens cDNA FLJ11481 fis, clone HE 63
420185 AL044056 Hs 158047 ESTε 63
415672 N53097 Hs 193579 ESTε 62
455488 AA102322 gb zl90f03 r1 Stratagene colon (937204) 62
420026 AI831190 Hs 166676 ESTε 61
446868 AV660737 Hs 135100 ESTs 61
431622 AW979271 Hs 293184 ESTs 6 1
407266 AJ235664 gb Homo sapiens mRNA for immunoglobulin 61
421300 AW297398 Hs 96617 ESTs 60
416045 H15990 Hs 31403 ESTs 60 414175 AI308876 Hs 103849 hypothetical protein DKFZp761D112 60
424693 BE169810 Hs 47557 ESTs 60
436397 AA715013 Hs 169835 ESTs 60
440504 A1948966 Hs 130017 ESTs Weakly similarto JN0908 H+-transp 60
409718 D86640 Hs 56045 src homology three (SH3) and cysteine π 60
403625 60
418986 AI123555 Hs 81796 ESTs 59
416035 H42314 gb yo09e02 s1 Soares adult brain N2b5HB5 59
400292 AA250737 Hs 72472 ESTs 59
442849 R10099 Hs 269805 ESTs 59
440887 AI799488 Hs 135905 ESTs 58
427535 R29543 Hs 2164 pro platelet basic protein (includes pla 57
410934 AW811114 gb MR2-ST0131-111199 016 a04 ST0131 Homo 57
431374 BE258532 Hε 251871 CTP synthase 57
444963 AI916973 Hs 213603 ESTs 57
447530 AW192063 Hs 248865 ESTs Moderately similar to JC5238 galx 56
444992 R37658 Hs 21375 ESTs 56
416575 W02414 Hs 38383 ESTs 55
431211 M86849 Hs 323733 gap junction protein, beta 2, 26kD (conn 55
451830 H18433 Hs 21542 KIAA1035 protein 55
446466 H38026 Hs 308 arrestin 3, retinal (X-aπestm) 55
404043 55
423454 AL110456 Hs 469 succinate dehydrogenase complex, subunit 55
455540 BE080231 gb RC4-BT0629-120200 012411 BT0629 Homo 55
434683 AW298724 Hs 202639 ESTs 55
445898 AF070623 Hs 13423 Homo sapiens clone 24468 mRNA sequence 55
422306 BE044325 Hs 227280 U6 snRNA-assxiated Sm-like protein 55
428895 AA437124 Hs 187247 ESTs 54
450018 AA421642 Hε 24309 hypothetical protein FLJ11106 54
419249 X14767 Hs 89768 gamma ammobutyπc acid (GABA) A recepto 54
455047 AW852530 gb PM1-CT0243 071099 001-g06 CT0243 Homo 54
454039 AW079064 Hs 245540 ESTs 53
403637 53
414725 AA769791 Hs 125300 nng finger protein 21, interferon respo 53
409073 AA063458 gb zf71a07 s1 Soareε_pιneal_gland_N3HPG 53
403329 53
434001 AW950905 Hs 3697 serine (or cysteine) proteinase inhibito 53
459664 53
401497 53
410797 AW857191 gb RC2-CT0304-080100 011-M2 CT0304 Homo 52
411402 BE297855 Hs 69855 NRAS related gene 52
448844 AI581519 Hs 177164 ESTs 52
435202 AI971313 Hs 170204 KIAA0551 protein 51
439418 AI282149 Hs 56213 ESTs Highly similar to FXD3.HUMAN FORKH 51
443584 AI807036 Hs 267245 hypothetical protein FLJ14803 51
434352 AF129505 Hs 86492 small muscle protein, X-lmked 51
430838 N46664 Hs 169395 hypothetical protein FLJ12015 51
430882 BE174240 Hs 79024 heterogeneous nuclear πboπucl∞protein 51
440129 AA865818 Hs 174936 ESTs, Weakly similar to S71886 Ste20-lιk 50
437636 AA764781 Hs 291844 ESTs 50
455747 BE074910 gb RC5-BT0580-170300-021-F12 BT0580 Homo 50
455464 AW983901 gb RC1-HN0003-220300-011-f10 HN0003 Homo 50
418771 AA807881 Hε 25329 ESTs 50
434820 AI821863 gb πs90f05 x5 NCI CGAP_Pr3 Homo sapiens 50
440615 AI733055 Hε 130806 ESTs 50
454482 BE147919 gb RC3-HT0230-160200016-a08 HT0230 Homo 49
400432 AX015809 Hε 287767 Sequence 8 from Patent WO9950285 49
436508 AW604381 Hε 121121 ESTs, Weakly similar to S00755 plxkstπ 49
423607 AA328329 Hs 6591 ESTs - 49
407415 AF073328 gb Homo sapiens tetrxylme tranεporter- 49
401878 49
443162 T49951 Hs 9029 DKFZP434G032 protein 49
451325 AA021283 Hs 59788 ESTs 49
440515 AJ131245 Hs 7239 SEC24 (S cerevisiae) related gene famil 49
406333 49
409105 AW467539 Hs 255877 ESTs
408000 L11690 Hs 620 bullous pemphigoid antigen 1 (230/240kD) 48
421482 AL135462 Hs 104715 inversm 48
442757 AI739528 Hs 28345 ESTs 48
459717 48
436637 AI783629 Hs 26766 ESTs 48
412222 AA528283 Hs 292737 ESTs 48
450101 AV649989 Hs 24385 Human hbc647 mRNA sequence 48
410901 AW810001 gb MR4-ST0124-270300005-bH ST0124 Homo 48
426217 AW131888 Hs 172792 ESTs, Weakly similar to hypothetical pro 48
441640 AI733345 Hs 144104 ESTs 48
422977 AA631498 gb np83h04 s1 NCI_CGAP_Thy1 Homo εapienε 48
425361 AA355933 Hs 132221 hypothetical protein FLJ12401 48
414955 C15506 gb C15506 Clontxh human aorta polyA+ mR 48
411965 BE467339 Hs 280115 ESTs 47
403341 47
411726 AW858612 gb CM3-CT0341-190400 152 h12 CT0341 Homo 47
443271 BE568568 Hs 195704 ESTs 47 417181 L10123 Hs 1071 surfactant protein A binding protein 47
426097 BE327369 Hs 112238 ESTs 47
439199 R40373 Hs 26299 ESTs 47
440728 AW086077 Hs 153272 Homo sapiens cDNA FLJ22715 fis clone H 46
434381 AA631834 gb np77h05 s1 NCI_CGAP_Pr2 Homo εapiens 46
417428 N87579 gb LL2030F Human fetal heart Lambda ZAP 46
431291 N25521 Hs 25275 Kruppel type zinc finger protein 46
431242 AA987742 Hs 251278 KIAA1201 protein 46
426985 BE394849 Hs 131905 ESTε Moderately similar to Z195 HUMAN Z 46
442360 AI374621 Hs 29055 ESTs 46
452171 AI863302 Hs 211930 EST 46
440801 AA906366 Hs 190535 ESTs 45
411738 AW859353 gb MR1-CT0353 150300 102 a12 CT0353 Homo 45
431447 AA505138 Hs 291341 ESTs 45
433485 AI493076 Hs 201967 aldo-keto reductase family 1 , member C2 45
401365 45
408281 BE141183 gb MR0 HT0071-191199 001 b04 HT0071 Homo 45
411657 AW855583 gb CM4 CT0278 221099-027407 CT0278 Homo 45
423065 R96158 Hs 267130 Homo sapiens clone MGC 5406, mRNA, comp 45
428528 AI004034 Hs 98638 ESTs 45
454036 AA374756 Hs 93560 Homo sapiens mRNA for KIAA1771 protein, 45
417252 AA195014 Hs 85971 ESTs 45
417135 AA422067 Hs 50547 ESTs 45
403089 44
420691 AA829433 Hs 275343 ESTs 44
412147 AW895984 gb QV4-NN0039 040500 197 e08 NN0039 Homo 44
425578 U65652 Hs 158313 chromosome 17 open reading frame 1 A 44
430403 AF039390 Hs 241382 tumor necrosis factor (ligand) superfami 44
454438 AA224053 Hs 172405 cell division cycle 27 44
435434 AA680387 Hs 187850 ESTs 44
420828 AA280778 Hs 186878 ESTs 43
435586 AI279137 Hs 151498 ESTs 43
452393 H87398 Hs 99858 ribosomal protein L7a 43
416170 H42454 Hs 220645 ESTs 43
408691 AW250525 gb 2821626 δpπme NIH.MGC.7 Homo sapiens 43
428912 AW103117 Hs 98949 ESTs, Weakly similar to MEA6 [H sapiens] 43
455511 BE144762 gb CM0 HT0180 041099 065-b04 HT0180 Homo 43
413849 BE173561 Hε 15384 AP1 gamma subunit binding protein 1 43
401189 43
425733 F13287 Hs 159388 Homo sapiens clone 23578 mRNA sequence 43
447863 AL047611 Hs 288885 Homo sapiens cDNA FLJ14246 fis, clone OV 43
422654 AA314316 Hs 163725 ESTs 43
435463 AA682507 gb zj18f08 s1 Soares fetal liver spleen_ 43
417919 AI928203 Hs 86379 ESTε 43
405784 43
431853 AA521034 Hs 70834 ESTs 43
409629 AW449589 Hs 279724 ESTs 42
403281 42
427173 BE255017 Hs 97540 ESTs 42
433717 AF063536 gb AF063536 Homo sapiens library (Yu Y) 42
406777 T23625 Hs 150580 putative translation initiation fxtor 42
410481 R34107 Hs 321450 pregnancy spxific beta 1-glycoproteιn 2 42
419511 AA429750 Hs 75113 general transcription factor IIIA 42
452291 AF015592 Hs 28853 CDC7 (cell division cycle 7, S cerevisi 42
449762 N93057 Hs 54888 ESTs 42
421106 AA877124 Hs 172844 ESTs 42
439382 BE247684 Hs 103070 ESTs 41
404957 41
436332 AL049679 Hs 82302 Homo sapiens cDNA FLJ 14814 fis, clone NT 41
446393 AW014174 Hs 301956 zinc finger protein 41
452728 AI915676 Hs 239708 ESTs 41
456386 W28481 gb 47e1 Human retina cDNA randomly prime 4 1
406288 AW068311 Hs 311054 Homo sapiens mRNA full length insert cDN 41
416972 BE019670 gb bb28c01 x1 NIH_MGC_5 Homo sapiens cDN 41
427099 AB032953 Hs 173560 odd Oz/ten m homolog 2 (Drosophila mous 41
403344 41
438993 AA828995 gb od77b08 s1 NCI_CGAP_Ov2 Homo εapienε 41
444922 AI921750 Hs 144871 Homo εapiens cDNA FLJ13752 fis, clone PL 41
401596 AA172106 Hs 110950 Rag C protein 41
418693 AI750878 Hε 87409 thramboεpoπdm 1 4 1
414299 AA142989 Hε 71730 ESTs 41
452744 A1267652 Hs 30504 Homo sapiens mRNA cDNA DKFZp434E082 (fr 40
458552 AW136139 Hε 245856 ESTs 40
421065 AA329711 gb EST33382 Embryo, 12 week II Homo sapi 40
439294 AW975328 Hs 6523 chromosome 1 open reading frame 12 40
441201 AW118822 Hs 128757 ESTs 40
434377 AW137148 Hs 306593 Homo sapiens cDNA FLJ 11382 fis, clone HE 40
440472 AA886169 Hs 169071 ESTs 40
418379 AA218940 Hs 137516 fidgetm like 1 40
435878 R08330 Hs 20152 ESTs 40
437263 AA747822 gb nx97a04 s1 CI CGAP GCB1 Homo sapiens 40
444087 AV647899 Hs 282375 ESTs 40
411745 AW867826 gb MRO SN0039 300300-001-c02 SN0039 Homo 40 438660 U95740 Hs 6349 Homo sapiens, clone IMAGE 3010666, mRNA, 40
405521 40
411597 AW852925 gb PMO CT0248-131099 001410 CT0248 Homo 40
415655 W05433 Hs 49890 ESTs 40
404822 40
441107 AA917075 Hs 190520 ESTs 40
404834 40
412768 AW996044 Hs 26239 Human DNA sequence from clone RP11-438B2 40
428102 AA968441 Hs 126866 ESTs 40
436511 AA721252 Hs 291502 ESTs 40
441247 AW118681 Hs 128051 Homo sapiens thymic stromal lymphopoieti 40
453098 Z25935 Hs 86379 ESTs 39
410811 AW805687 Hs 300648 ESTs 39
425048 H05468 Hs 164502 ESTs 39
431071 AA491379 gb aa65f05 r1 NCI CGAP.GCB1 Homo sapienε 39
436298 AW293496 Hs 180138 ESTs 39
440356 AI933184 Hs 127922 ESTs, Moderately similar to S65657 alpha 39
452768 AW069459 Hs 61539 ESTs 39
455241 AW876249 gb PM4-PT0019 131299 006-B05 PT0019 Homo 39
409070 AA063003 Hs 224560 ESTs 39
409044 AI129586 Hs 33033 hypothetical protein FLJ14623 39
419091 T85332 Hs 178294 ESTs 39
422591 L07648 Hs 118630 MAX-interacting protein 1 39
403188 39
418857 D10216 Hs 89394 POU domain, class 1, transcnption fxto 39
413585 AI133452 Hs 75431 fibrinogen, gamma polypeptide 39
436149 AI754308 Hs 159452 ESTs 39
443682 AI383061 Hs 47248 ESTs, Highly similar to similar to Cdc14 39
437916 BE566249 Hs 20999 hypothetical protein FLJ23142 39
439818 AL360137 Hs 19934 Homo sapienε mRNA full length insert cDN 39
438361 AA805666 Hs 146217 Homo sapiens cDNA FU23077 fis, clone L 39
451221 AI949701 Hs 210589 ESTs 39
455475 AW948126 gb RCO-MT0013-280300 031-a12 MT0013 Homo 39
433197 AB040889 Hs 281022 KIAA1456 protein 39
429881 T80112 Hs 192245 ESTs 39
415588 AI433165 Hs 9856 ESTs 39
431220 N52937 Hs 102679 ESTs 39
433132 AB026264 Hs 284245 hypothetical protein IMPACT 39
424029 AB014594 Hs 137579 KIAA0694 gene product 39
404443 39
407340 AA810168 Hs 284289 vitiligo-associated protein VIT-1 39
410318 AA084050 Hs 269259 ESTε, Weakly similar to S23650 retroviru 39
412400 AW948066 gb RCO MT0012-290300-031-h10 MT0012 Homo 39
427167 AI239607 Hs 99196 hypothetical protein MGC11324 39
438090 AA777534 Hs 191992 ESTs 38
407938 AA905097 Hs 85050 phospholamban 38
440454 AI733037 Hs 129990 ESTs 38
417706 T90797 Hs 268623 ESTs 38
428692 AI372822 Hs 110103 RNA polymerase I transcnption factor RR 38
407762 AW235638 Hs 29475 ESTs 38
420727 H75701 Hs 99886 complement component 4-bιndιπg protein, 38
417508 BE163512 Hs 180877 H3 histone, family 3B (H33B) 38
413525 BE145899 gb MRO-HT0208 221298-204-b10 HT0208 Homo 38
425798 AA364002 gb EST74529 Pineal gland II Homo sapiens 38
459429 AA278779 Hs 335696 EST 38
430205 AB025904 Hs 235168 carbonic anhydrase XIV 38
437458 AL390131 Hs 128751 Homo sapienε cD A FLJ 12235 fis, clone MA 38
451073 AI758905 Hs 206063 ESTs 38
452786 R61362 Hs 106642 ESTs, Weakly similar to T09052 hypotheti 38
429846 AB023021 Hs 225945 fucosyltransferase 9 (alpha (1 ,3) fucosy 38
444414 AW293214 Hs 8752 transmembrane protein 4 38
402615 37
410585 AW770523 Hs 337501 ESTs 37
425168 R96366 gb yq37d04 s1 Soares fetal liver spleen 37
449729 R72032 Hs 28235 ESTs 37
459359 N99545 gb za40a05 r1 Soares fetal liver spleen 37
456443 AW967500 Hs 133543 ESTε 37
439001 AF075068 gb Homo εapienε full length insert cDNA 37
443657 R14973 gb yf42f10 s1 Soares fetal liver εpleen 37
404193 37
416379 N38857 Hs 203933 ESTε 37
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 37
426603 AA382291 gb EST95683 Teεtis I Homo sapiens cDNA 5 37
412589 R28660 Hs 24305 ESTs 37
421037 AI684808 Hs 197653 ESTs 37
427088 AA398085 Hs 142390 ESTs 37
429927 NM 001115 Hs 2522 adenylate cyclase 8 (brain) 37
453375 AI980114 Hs 240091 ESTs 37
435451 AF185420 Hs 303006 ESTs, Weakly similar to gamma heregulm 37
451882 AI821324 Hs 100445 ESTs 37
419983 W55956 Hs 94030 Homo sapiens mRNA, cDNA DKFZp586E1624 (f 37
405001 U58196 Hs 296281 interleukin enhancer binding fxtor 1 37
422182 AL043892 Hs 180582 Homo sapiens cDNA FLJ21836 fis, clone H 37 451917 AW391351 Hs 50820 Homo sapiens unknown mRNA 37
432781 NM.014133 Hs 278940 PRO0618 protein 37
443773 AV646452 Hs 30941 calcium channel voltage dependent, beta 37
406964 M21305 gb Human alpha satellite and satellite 3 37
430682 AW971949 Hs 291252 ESTs, Weakly similar to ZN91.HUMAN ZINC 37
449804 AI535663 Hs 39379 ESTε 37
411505 AF155659 Hs 70565 molybdenum cofactor εynthesis 2 37
430503 AA533574 Hs 152274 ESTs 37
443305 AI050693 Hs 133318 ESTs 37
415076 NM 000857 Hs 77890 guanylate cyclase 1, soluble, beta 3 37
452280 AI911410 Hs 167224 ESTs 36
432189 AA527941 gb nh30c04 s1 NCI_CGAP_Pr3 Homo sapiens 36
406992 S82472 gb beta -pol=DNA polymerase beta {exon a 36
441416 AI990139 Hs 148609 ESTs 36
448776 BE302464 Hs 30057 MRS2 (S cerevιsιae)-lιke, magnesium hom 36
413998 AW103807 Hs 243933 ESTs 36
440385 AA884283 Hs 192136 ESTs 36
431673 AW971302 Hs 293233 ESTs 36
401887 36
404793 36
422054 AA322506 gb EST25146 Cerebellum II Homo sapienε c 36
432030 AI908400 Hs 143789 ESTs 36
449645 AI961092 Hs 196155 ESTs 36
404476 36
449336 AL119995 Hε 15260 ESTs Highly similar to AC0072282 BC372 36
401200 36
403937 36
437918 AI761449 Hε 121629 ESTs 36
443394 AI055865 Hs 133485 ESTs 36
439107 AL046134 Hs 13944 adrenergic, beta, receptor kinase 2 36
417229 AA975096 Hs 19522 hypothetical protein PR02849 36
425403 AL023753 Hs 156406 Human DNA sequence from clone 1198H6 on 36
436269 AA707472 Hs 190760 ESTs 36
453823 AL137967 gb DKFZp761D2315_r1 761 (synonym hamy2) 36
416394 H64111 gb yr57f03 r1 Soareε fetal liver εpleen 36
432779 AW979241 gb EST391351 MAGE reεequences, MAGP Homo 36
439326 W07140 Hs 54721 ESTs 36
423035 AW449679 Hs 156739 H sapiens XG mRNA (clone PEP11) 36
435766 R11673 Hs 186498 ESTs 36
448067 R68568 Hs 183373 src homology 3 domain-containing protein 36
441605 AA984647 Hs 128801 ESTs 35
414400 X06948 Hs 897 Fc fragment of IgE, high affinity I, rx 35
418405 AI868282 Hs 11898 ESTε, Highly similar to KIAA1370 protein 35
437642 AL079309 gb Homo sapienε mRNA full length insert 35
450350 T97817 Hs 174880 ESTs 35
451704 AI755209 Hs 205616 ESTs, Weakly similar to ALULHUMAN ALU S 35
459037 AW439497 Hs 290656 EST 35
419247 S65791 Hs 89764 fragile X mental retardation 1 35
423121 AW864848 gb PM2-SN0018-290300-003-C09 SN0018 Homo 35
426724 AA383623 Hs 293616 ESTs 35
434273 AA913143 Hs 26303 ESTs 35
438042 AW296971 Hs 255593 ESTs 35
410500 R09442 gb yf26c09 r1 Soares fetal liver spleen 35
416154 Z46122 gb HSC0VB031 normalized infant brain cDN 35
418432 M14156 Hs 85112 insulin like growth fxtor 1 (somatomedi 35
454447 BE163567 gb QV3-HT0460-230200-101-b08 HT0460 Homo 35
458067 AA393603 Hs 36752 protein kinase anchoring protein GKAP42 35
444338 AI937026 Hs 146642 ESTs 35
427687 AW003867 Hs 1570 histam e rxeptor H1 35
415929 AA724373 Hε 49344 hypothetical protein FLJ 11006 35
416009 Z43062 gb HSC12E041 normalized infant brain cDN 35
421515 Y11339 Hs 105352 GalNAc alpha 2, 6-sιalyltransferase I, I 35
403515 35
435783 AB037734 Hs 4993 KIAA1313 protein 35
439953 AA918129 Hs 124638 ESTε 35
457620 AA602711 Hs 336753 EST 35
442006 AW975183 Hs 292663 ESTs, Weakly similar to S72482 hypotheti 35
453931 AL121278 Hs 25144 ESTs 35
453128 AW026516 Hs 31791 acylphoεphatase 2, muscle type 35
413468 BE504766 gb hz40g01 x1 NCI CGAP GC6 Homo sapiens 35
454600 AW810001 gb MR4-ST0124-270300 005 b11 ST0124 Homo 35
451065 AW295132 Hs 222231 ESTs, Weakly similar to granule cell mar 35
444493 R59410 Hs 282094 ESTs, Moderately similar to I38022 hypot 35
426447 AV655843 Hs 169919 electron-transfer-flavoprotem, alpha po 35
410908 AA121686 Hs 10592 ESTε 35
440364 AA910460 Hs 128626 ESTs 35
406190 35
430762 AI343652 Hs 105667 ESTs 35
451182 D52562 Hs 296317 KIAA1789 protein 34
432437 W07088 Hs 293685 ESTs 34
442137 AA977235 Hs 128830 ESTs, Weakly similar to Z192.HUMAN ZINC 34
405970 34
407676 AW064111 Hs 279823 ESTs 34 413141 BE166323 gb QV4-HT0492-270100 086-e12 HT0492 Homo 34
431418 X68242 Hs 252722 Hιn-1 34
431954 AK001974 Hs 272242 hypothetical protein FLJ11112 34
459371 R20991 gb yg06h01 r1 Soares infant brain 1NIB H 34
428062 AA420683 Hs 98321 hypothetical protein FLJ14103 34
423841 AW753967 gb RC2-CT0304-080100 011-h12 CT0304 Homo 34
420430 A1703192 gb wd92h04 x1 NCI CGAP Lu24 Homo sapiens 34
443921 AI091310 Hs 134848 ESTs 34
444453 AW379394 Hs 145126 ESTs 34
443475 AI066470 Hs 134482 ESTs 34
414136 AA812434 Hs 119023 SMC2 (structural maintenance of chromoεo 34
453263 R91778 Hs 99369 ESTs 34
410888 AW861207 gb RC1-CT0302-120200 013-d04 CT0302 Homo 34
456303 AA224872 Hs 115088 ESTs 34
431474 AL133990 Hs 190642 ESTs 34
439702 AW085525 Hs 134182 ESTs 34
458797 AW001835 Hs 13323 hypothetical protein FLJ22059 34
430140 AW296771 Hs 221999 ESTs 34
423871 AA331906 gb EST35805 Embryo, 8 week I Homo sapien 34
459278 AW294659 Hs 34054 Homo sapiens cDNA FLJ22488 fis, clone H 34
446672 T05514 gb EST03403 Fetal brain, Stratageπe (cat 34
431548 AI834273 Hs 9711 novel protein 34
416182 NM 004354 Hs 79069 cyclin G2 34
422899 D16471 Hs 121571 Human mRNA, Xq terminal portion 34
417663 R07483 Hs 180461 ESTs 33
405455 33
426235 AI631964 Hs 34447 ESTs 33
439567 AI056618 Hs 134314 ESTs 33
444848 AW4511 6 Hs 195954 ESTs 33
451426 AW205003 Hs 208063 ESTs 33
408172 W02488 Hs 46039 phosphoglycerate mutase 2 (muscle) 33
401626 33
405780 33
417991 AA731452 Hs 190008 ESTs 33
443212 AW269515 Hs 102500 hypothetical protein FLJ20481 33
403356 33
404518 AI815601 Hs 79197 CD83 antigen (activated B lymph∞ytes, I 33
413581 BE150618 gb RC3-HT0272-110100 013-C06 HT0272 Homo 33
426701 AI968103 Hs 209461 Homo εapieπε cDNA FLJ12836 fis, clone NT 33
445510 AA946676 Hs 282824 ESTs 33
418663 AK001100 Hs 41690 desmocollm 3 33
447617 AI400762 Hs 176675 ESTs 33
448150 AI472167 Hs 302739 ESTs 33
410140 AL134435 Hs 22269 πeurexm 3 33
443283 BE568610 gb 601342622F1 NIH MGC 53 Homo sapiens c 33
454777 AW820027 gb QV0-ST0294-240300-173-g04 ST0294 Homo 33
410767 AJ001873 Hs 66185 Homo Sapiens mRNA, partial cDNA εequence 33
433183 AF231338 Hs 222024 tranεcπption fxtor BMAL2 33
436168 AK000883 Hs 301645 Homo εapiens cDNA FLJ10021 fis, clone HE 33
438456 AA913381 Hs 190513 ESTs 33
411186 AW821257 gb PM3-ST0307-231299-001-b11 ST0307 Homo 33
411880 AW872477 gb hm30f03 x1 NCI_CGAP_Thy4 Homo sapiens 33
433567 AF073299 Hs 103132 εolute earner family 9 (sodium/hydrogen 33
433805 AA706910 Hs 112742 ESTs 33
409434 AF278761 Hs 131581 Homo sapiens testiε transcπpt Y 7 (TTY7 33
440184 AB002297 Hs7022 dedicator of cyto-kmesis 3 33
456555 AW592167 Hs 293299 ESTs 33
419189 T95862 Hs 112318 62 kd protein 33
428648 AF052728 Hs 188021 potasεium voltage-gated channel, subfami 33
407995 A1094748 Hs 100134 hypothetical protein FLJ 12787 33
413200 AA127395 Hs 222414 ESTε 33
416421 AA134006 Hs 79306 eukaryotic translation initiation factor 33
416737 AF154335 Hs 79691 UM domain protein 33
428356 AL046991 Hs 10338 ESTs 33
428216 AI369472 Hs 65407 ESTs 33
432488 AA551010 Hs 216640 ESTs 33
433386 AW360833 gb PM1-CT0243-201099-004 d08 CT0243 Homo 33
400889 33
416294 D86980 Hs 79170 KIAA0227 protein 33
446190 AI279299 Hs 256564 ESTs 33
417801 AA417383 Hs 82582 integnn, beta-like 1 (with EGF-like rep 33
418122 R42778 Hs 22217 Homo sapienε clone IMAGE 32106, mRNA seq 33
418375 NM 003081 Hs 84389 synaptoεomal-ass∞iated protein, 25kD 33
443367 AW071349 Hs 215937 ESTs 33
446645 AI336596 Hs 156294 ESTs 33
434294 AJ271379 Hs 76194 πbosomal protein S5 33
452372 A1885742 Hs 228474 ESTs 33
414241 AA425085 Hs 4007 Sarcolemmal-assxiated protein 32
436982 AB018305 Hs 5378 spondm 1, (f-spondiπ) extracellular mat 32
430548 AW450575 Hs 163203 ESTs, Weakly similar to B34087 hypotheti 32
427119 AW880562 Hs 114574 ESTs 32
437073 AI885608 Hs 94122 ESTs 32
437845 AA769578 Hs 90488 ESTs 32 454962 AW847645 gb 1L3 CT0213-280100-056-A04 CT0213 Homo 32
414394 AI904738 Hs 76053 DEAD/H (Asp-Glu-Ala-Asp/His) box polypep 32
417175 R44558 Hs 94002 ESTs 32
456536 AW135986 Hs 257859 ESTs 32
401132 32
407764 BE008347 gb CM0-BN0154-080400-325-h04 BN0154 Homo 32
428004 AA449563 Hs 151393 glutamate cysteine ligase, catalytic sub 32
450947 AI745400 Hs 204662 ESTs 32
456605 AI827786 Hs 259044 ESTs 32
452879 AW905328 Hs 180842 πbosomal protein L13 32
454754 AW819191 gb CM1-ST0283 071299-061-d08 ST0283 Homo 32
429479 AA453488 Hs 99333 ESTs 32
448090 AI608821 Hs 270289 ESTs 32
401324 32
404731 32
419936 AI792788 gb ol91d05 y5 NCI CGAP_Kιd5 Homo sapiens 32
455571 BE003714 gb QV3-BN0096-200400-161-a01 BN0096 Homo 32
433990 AA889328 Hs 112950 ESTs 32
415239 R42608 Hs 139270 ESTs 32
418878 W20080 Hs 6616 ESTs 32
438079 R09664 Hs 191223 ESTs 32
422183 AA431698 Hs 112794 Human DNA sequence from clone 1068E13 on 32
457460 AI143312 Hs 129206 casein kmase 1, gamma 3 32
454145 AA046872 Hs 62798 ESTs 32
446577 AB040933 Hs 15420 KIAA1500 protein 32
430664 AW969834 Hs 303303 ESTs 32
404588 32
407834 AW084991 Hs 26100 ESTs 32
413087 BE064655 gb RC1-BT0313-301299-012-C09 BT0313 Homo 32
440790 AW593050 Hs 128580 ESTs 32
452081 AW958859 Hs 7514 Homo sapiens cDNA FLJ12141 fis, clone MA 32
421916 R34441 Hs 101007 Homo sapienε cDNA FLJ23546 fiε, clone L 32
419261 X07876 Hs 89791 wingless-type MMTV integration site fami 32
419340 AA236590 Hs 87530 ESTs 32
444771 AB023201 Hs 11912 KIAA0984 protein 32
445233 AV653034 Hs 297559 ESTs 32
457030 AI301740 Hs 173381 dihydropyπmidinaεe-like 2 32
408334 AW514652 Hs 321637 ESTs 32
410085 AA428482 Hs 58589 glycogenm 2 32
411018 AW813428 gb MR3-ST0192-010200-210-C05 ST0192 Homo 32
403623 32
432223 AA333283 Hs 121001 Homo sapienε, clone IMAGE 3460280, mRNA 32
444050 AW138295 Hs 135024 ESTε 32
421036 AA810560 Hs 303577 ESTs 32
401459 3 1
404404 3 1
450438 AI696071 Hs 253800 ESTs 31
414523 AU076633 Hs 76353 senne (or cysteine) proteinase inhibito 3 1
419169 AW851980 Hs 262346 ESTs, Weakly similar to S72482 hypotheti 3 1
441274 AW593781 Hs 131357 ESTs 31
450785 AA852713 Hs 25459 Homo sapienε, alpha-1 (VI) collagen 3 1
452401 NM.007115 Hs 29352 tumor necrosis fxtor, alpha-induced pro 31
400816 31
410307 AF022913 Hs 62187 phosphatidylmositol glycan, class K 3 1
431906 AW328038 Hs 37486 ESTs 31
440046 AW402306 Hs 6877 hypothetical protein FLJ10483 31
450271 AI693900 Hs 200920 ESTε 3 1
415811 AA450191 Hs 172963 hypothetical protein FLJ14624 31
415273 Z39840 Hs 22229 ESTs 3 1
450519 AA010066 Hs 224849 Homo sapiens cDNA FLJ 12583 fis, clone NT 31
451421 W16522 Hs 237689 Homo sapiens cDNA FU13539 fis, clone PL 31
446364 AB006624 Hs 14912 KIAA0286 protein 31
436638 A1271945 Hs 134984 ESTs 31
418079 R40058 Hs 6911 ESTs 3 1
448466 AI522109 Hs 171066 ESTs 31
448835 BE277929 Hs 11081 UBX domain-containing 2 3 1
415046 R40018 Hs 56400 ESTs 31
448134 AI470790 Hs 34494 ESTs 31
456027 BE327387 Hs 13913 KIAA1577 protein 31
458023 AW978161 Hs 268555 5'-3' exoπbonucleaεe 2 31
417079 U65590 Hs 81134 interleukin 1 receptor antagonist 31
421308 AA687322 Hs 192843 leucine zipper protein FKSG14 3 1
414884 R54418 Hs 183745 hypothetical protein FLJ13456 31
449138 AW294215 Hs 195631 ESTs 3 1
455756 BE079307 gb RC1-BT0623-120200-011-g09 BT0623 Homo 3 1
428170 H05530 Hε 12565 ESTs 31
429878 AA460188 Hε 127263 ESTε 3 1
455000 AW850283 Hs 324429 Homo εapiens cDNA FLJ14015 fis, clone HE 31
438369 T77886 Hs 83428 nuclear factor of kappa light polypeptid 31
415840 R15955 Hs 21758 ESTs 3 1
444955 AW002844 Hs 148641 ESTs 3 1
436020 AA778177 Hs 121724 ESTs 31
453051 AW196690 Hs 224269 ESTε 31 425178 H16097 Hs 161027 ESTs 3 1
402145 3 1
410685 AA497117 Hs 129600 ESTs, Moderately similar to ALULHUMAN A 31
449238 AA428229 Hs 331561 muscle-specific RING-finger protein 3 31
456737 BE247203 Hs 124831 CGI-67 protein 3 1
438214 H06076 Hs 26320 TRABID protein 3 1
436250 AY004867 Hs 85844 neurotrophic tyrosine kinase, receptor, 31
411622 AI807894 Hs 47274 Homo sapiens mRNA, cDNA DKFZp564B176 (fr 30
418454 AA315308 Hs 195870 hypothetical protein FLJ14991 30
449357 AI076363 Hs 288806 Homo sapiens cDNA FLJ11778 fis, clone HE 30
418950 T78517 Hs 13941 ESTs 30
431508 NM.012481 Hs 182979 πbosomal protein L12 30
405090 30
445409 AI949081 Hs 147862 ESTs 30
452778 R71338 Hs 5921 Homo sapiens cDNA FLJ21592 fis, clone C 30
455577 BE006341 gb RC2-BN0127-240300-011-b05 BN0127 Homo 30
408235 AA053381 Hs 75969 proline-rich protein with nuclear target 30
436194 AK001074 Hs 333435 Homo εapiens cDNA FLJ10212 fis, clone HE 30
452073 AA625150 Hs 82098 ESTs 30
427050 AA397789 Hs 161803 ESTs 30
427244 AA402400 Hs 1 8045 ESTs 30
448405 AW207634 Hs 170849 ESTs 30
433767 AA609245 gb af13a11 s1 Soares testiε NHT Homo sap 30
421376 AA287948 Hs 134110 ESTs 30
441519 AA972740 Hs 127092 ESTs 30
404367 30
453502 AL039786 Hs 21273 transcription factor NYD-sp10 30
421948 L42583 Hs 334309 keratin 6A 30
438165 AA779344 Hs 138136 ESTs, Weakly similar to 1510254A L1 repe 30
400608 30
404042 30
405229 30
411411 AA345241 Hs 55950 ESTs, Weakly similarto KIAA1330 protein 30
415452 F09134 Hs 12839 ESTs 30
430371 D87466 Hs 240112 KIAA0276 protein 30
447046 AA326187 Hs 17170 G protein-coupled rxeptor 4 30
455851 BE146879 gb QV4-HT0222-261099 014-.11 HT0222 Homo 30
429014 AI800518 Hs 118158 ESTs 30
405605 30
400227 30
439037 AF075084 gb Homo sapiens full length insert cDNA 30
439693 AI741816 Hs 125897 ESTs 30
427533 R36022 Hs 179566 hypothetical protein FLJ22624 30
418355 L42563 Hs 1165 ATPase, H+/K+ transporting, nongastπc, 30
433536 A1732163 Hs 188909 ESTs, Weakly similar to alternatively sp 30
448446 AI521251 Hs 171030 ESTs 30
449623 C00719 Hs 120440 EST 30
445568 H00918 Hs 268744 KIAA1796 protein 30
440448 AA885428 Hs 125646 ESTs 30
428201 AA424158 Hs 206461 ESTs 30
444148 AW003204 Hs 151167 ESTs 30
447972 AL137275 Hs 20137 hypothetical protein DKFZp434P0116 30
432584 AA928829 Hs 47099 hypothetical protein FLJ21212 30
440925 AW511090 Hs 130419 ESTs 30
428398 AI249368 Hs 98558 ESTs 30
415913 H70302 gb yr95f07 r1 Soares fetal liver spleen 30
418145 AF121260 Hs 83577 cysteine and glycine-πch protein 3 (car 30
413252 BE074910 gb RC5-BT0580-170300-021-F12 BT0580 Homo 30
400335 Y13187 Hs 248067 Homo εapienε dmd gene, intron 11 30
426132 AA370501 gb EST82261 Proεtate gland 1 Homo sapien 30
436938 AW139680 Hs 161393 ESTs 30
437980 R50393 Hs 278436 KIAA1474 protein 30
455955 BE162394 gb P 2-HT0451-170100-004-a08 HT0451 Homo 30
414899 AW975433 Hs 36288 ESTs 29
403786 29
430187 AI799909 Hs 158989 ESTs 29
451700 AI470262 Hs 29553 ESTs 29
455866 BE149024 gb CM0-HT0249-291099-084^04 HT0249 Homo 29
445900 AF070526 Hs 13429 Homo sapienε clone 24787 mRNA sequence 29
457041 AA399018 Hs 250835 ESTs 29
415716 N59294 Hs 179662 nucleosome assembly protem 1-lιke 1 29
422336 AI761322 Hs 115285 dihydrolipoamide S-acetyltransferase (E2 29
451664 AA889081 Hs 153952 5' nucleotidase (CD73) 29
407244 M10014 Hs 75431 fibrinogen, gamma polypeptide 29
455249 AW876538 gb RC3-PT0028-190100-012-b06 PT0028 Homo 29
428862 NM 000346 Hε 2316 SRY (sex determining region Y)-box 9 (ca 29
406076 AL390179 Hs 137011 Homo sapienε mRNA, cDNA DKFZp547P134 (fr 29
405302 29
400325 M85292 Hs 247924 Homo εapiens endogenous HIV-1 related se 29
408408 AF070571 Hs 44690 Homo sapiens clone 24739 mRNA sequence 29
423119 AA322201 Hs 131976 ESTs 29
424152 AL133591 Hs 141480 Homo sapiens mRNA, cDNA DKFZp434N079 (fr 29
431980 AA523696 Hs 324507 hypothetical protein FLJ20986 29 425783 AA363946 Hs 20969 ESTs 29
401462 29
458817 AI522129 Hs 173119 ESTε 29
422163 AF027208 Hs 112360 prominiπ (mouse) like 1 29
419875 AA853410 Hs 93557 proenkephalm 29
423047 NM 005323 Hs 123064 H1 histone family, member T (testis spec 29
425349 AA425234 Hs 79886 ribose 5 phosphate isomerase A (ribose 5 29
401368 29
418531 R96760 Hs 183758 ESTs 29
447290 AI476732 Hs 263912 ESTs 29
441143 AI027604 Hs 159650 ESTs 29
431292 AA370141 Hs 2281 chromogranin B (secretograπm 1) 29
405783 29
444459 AI680624 Hs 148676 ESTs 29
402112 R58624 Hs 2186 eukaryotic translation elongation factor 29
425745 U44060 Hs 14427 Homo sapiens cDNA FLJ21800 fis, clone H 29
444827 R09764 Hs 20416 ESTε 29
451195 U10492 Hs 438 meseπchyme homeo box 1 29
411417 AW845481 gb MR1-CT0056 201199 008 b04 CT0056 Homo 29
418343 AA216372 Hs 159501 ESTs 29
431595 AA508196 gb nh60f07 s1 NCI.CGAP.Pr8 Homo sapiens 29
436187 AK000998 Hs 297221 Homo sapiens cDNA FLJ10136 fis, clone HE 29
455699 BE068121 gb CM1-BT0368 061299 060-a02 BT0368 Homo 29
459440 BE048054 gb tz46c03 y1 NCI CGAP_Brn52 Homo sapien 29
428832 AA578229 Hs 324239 ESTs, Moderately similar to ZN9LHUMAN Z 29
423492 AF020761 Hs 129683 ubiquitm-conjugating enzyme E2D 1 (homo 29
424235 NM 003181 Hs 143507 T brxhyury (mouse) homolog 29
437913 AI140825 Hs 121623 ESTs 29
443185 NM 006134 Hs 284142 chromosome 21 open reading frame 4 29
443458 R05385 Hs 143509 hypothetical protein FLJ21924 29
426803 AA362568 Hs 179747 ecotropic viral integration site 5 29
437183 AI928184 Hs 122011 ESTs 29
420879 N31165 Hs 238837 ESTs Weakly similar to S43603 RNA bmdi 29
442726 AW136066 Hs 19145 ESTs 29
456189 H91010 Hs 44940 ESTs 29
441115 R69910 Hs 29041 Homo sapiens cDNA FLJ14177 fis, clone NT 29
435563 AF210317 Hs 95497 solute earner family 2 (facilitated glu 29
415628 F13080 gb HSC3ID041 normalized infant brain cDN 29
423637 AL137279 Hs 130187 Homo sapienε mRNA, cDNA DKFZp43401214 (f 29
443246 T75157 Hs 337603 ESTε, Weakly similarto T08680 hypotheti 29
450877 AI799608 Hs 29178 ESTs 29
439063 AF085922 Hs 113968 ESTs 29
401526 29
408751 N91553 Hs 258343 ESTs 29
417320 AA195667 Hs 86022 ESTs 29
442927 AI024347 Hs 131519 ESTs 29
444125 AI124882 Hs 118121 ESTs 29
452148 AF007143 Hs 28205 Homo sapiens clone 23738 mRNA sequence 29
453901 BE065902 gb RC2-BT0318-150200-011-b09 BT0318 Homo 29
452589 BE159915 Hε 61406 ESTs, Weakly similar to 2004399A chromos 28
403011 28
436154 AA764950 Hs 119898 ESTs 28
408221 AA912183 Hs 47447 ESTs 28
430345 AK000282 Hs 239681 hypothetical protein FLJ20275 28
415399 T26994 Hs 177198 ESTε 28
441817 AW969706 Hs 293332 ESTs 28
443556 AA256769 Hs 94949 methylmalonyl CoAepimerase 28
455092 BE152428 gb C 0-HT0323-151299-126-b04 HT0323 Homo 28
439703 AF086538 Hs 196245 ESTs 28
411024 BE062590 gb QV1-BT0260-281099-023-f05 BT0260 Homo 28
414546 BE379492 gb 601236215F1 NIH_MGC_44 Homo sapiens c 28
434715 BE005346 Hs 116410 ESTs 28
407594 AW057584 Hs 160681 ESTs 28
439235 N45513 Hs 46608 ESTs 28
453736 AL118674 Hε 34871 zinc finger homeobox 1B 28
404967 28
437783 AI683150 Hs 201550 ESTε, Weakly similar to ALU1 HUMAN ALU S 28
412887 BE007420 gb PM3-BN0142-200300-001-C04 BN0142 Homo 28
426942 AA393551 Hs 97450 ESTs 28
403513 28
419077 AA233885 Hs 164526 ESTs 28
421823 N40850 Hs 28625 ESTs 28
425664 AJ006276 Hs 159003 transient rxeptor potential channel 6 28
451007 H38108 Hs 32759 ESTs 28
407803 AW081681 Hs 269064 ESTs, Weakly similar to T42689 hypotheti 28
409642 AW450809 Hs 257347 ESTs 28
439492 AF086310 Hs 103159 ESTs 28
420814 AA721156 Hs 190440 ESTs 28
449508 AK001566 Hs 23618 hypothetical protein FLJ 10704 28
428350 AW873520 Hs 112017 GE36 gene 28
405456 28
442459 AI264628 Hs 125428 ESTs 28
415763 Z42285 Hs 5181 proliferation associated 2G4, 38kD 28 428532 AF157326 Hs 184786 TBP interxting protein 28
436720 AW975902 gb EST388011 MAGE resequences, MAGN Homo 28
449539 W80363 Hs 58446 ESTs 28
415533 T74009 Hs 268738 ESTs, Weakly similar to ALU7_HUMAN ALU S 28
408749 H65489 Hs 250659 ESTs 28
404652 28
423130 AW897586 Hs 21213 ESTs 28
424960 BE245380 Hs 153952 5' nucleotidase (CD73) 28
402131 28
419530 X98330 Hs 90821 ryanodme rxeptor 2 (cardiac) 28
456118 AA380267 Hε 78277 DKFZP434F2021 protein 28
444217 AV648751 Hs 282395 ESTs 28
449579 AW207260 Hs 134014 ESTs Weakly similar to T46425 hypotheti 28
412323 AW937143 gb PM1-DT0041-281299 001401 DT0041 Homo 28
418912 NM 000685 Hs 89472 angiotensin receptor 1 28
433513 AI566356 Hs 171437 ESTs 28
448912 D83781 Hs 22559 KIAA0197 protein 28
451496 AW503407 gb UI-HF-BN0 akw-d-11-0-UI r1 NIH.MGC.50 28
420273 AI652864 Hs 197257 ESTs 28
451949 U03884 Hs 463 potassium inwardly rectifying channel, s 28
420756 AA411800 Hs 189900 ESTε 28
423532 BE090503 gb RC6 BT0717-110400-011-F11 BT0717 Homo 28
425012 T77666 Hs 92414 Homo sapiens cDNA FLJ22030 fis, clone H 28
441609 AA946764 Hs 133460 ESTs 28
448870 BE181783 Hs 175358 ESTs, Weakly similar to A47582 B ceil gr 28
451206 H86228 Hs 271780 ESTs, Weakly similar to I38022 hypotheti 28
457314 AA479597 Hs 193669 hypothetical protein DKFZp586J1119 28
416192 NM 005036 Hε 998 peroxisome proliferative activated rxep 28
418888 AU076801 Hs 89436 cadhenn 17, LI cadhenn (liver-mtestin 28
455310 AW893961 gb RC4-NN0027 060400 011-d11 NN0027 Homo 28
459450 AA426429 Hs 98463 EST 28
424188 AW954552 Hs 142634 zinc finger protein 27
423575 C18863 Hs 163443 Homo sapiens cDNA FLJ 11576 fis, clone HE 27
427443 AA402713 Hs 97872 ESTs 27
452092 BE245374 Hs 27842 hypothetical protein FLJ11210 27
413091 BE065063 gb RC1-BT0313 110500-017-e02 BT0313 Homo 27
421003 T72080 Hs 95667 F-box protein 30 27
429593 AK000332 Hs 209927 Homo εapiens cDNA FLJ20325 fis, clone HE 27
445611 AW418497 Hs 145583 ESTs 27
412494 AL133900 Hs 792 ADP-nbosylafion factor domain protein 1 27
408243 Y00787 Hs 624 interleukin 8 27
407308 H67394 Hs 331325 ESTs, Weakly similar to I38022 hypotheti 27
423728 AW891294 Hs 132136 solute camerfamily 4, sodium bicarbon 27
404587 M99587 Hs 104134 homeo box (H6 family) 1 27
410483 BE163567 gb QV3-HT0460-230200-101-b08 HT0460 Homo 27
416431 AW384459 Hs 172004 titin 27
416805 F13271 Hs 79981 Human clone 23560 mRNA sequence 27
417177 NM 004458 Hs 81452 fatty-acid-Coenzyme A ligase, long-chain 27
427134 AA398409 Hs 173561 EST 27
428137 AA421792 Hs 170999 ESTs 27
430844 T94960 gb ye38d07 r1 Stratagene lung (937210) H 27
441218 BE327561 Hs 202345 ESTs 27
440911 AA909536 Hs 143562 ESTs 27
411131 AW819212 gb CM1-ST0283-071299-061-C07 ST0283 Homo 27
438602 AI167149 Hs 123374 ESTs, Weakly similar to manner transpoε 27
441191 AI693930 Hs 148816 ESTs 27
403776 27
420159 AI572490 Hs 99785 Homo sapiens cDNA FLJ21245 fis, clone C 27
427839 AA608823 Hs 98244 ESTs 27
429905 AL080128 Hs 225998 DKFZP434C153 protein 27
449396 BE169100 Hs 195029 ESTs 27
450777 AA255646 Hs 60478 ESTs, Moderately similar to S47073 finge 27
458043 AW979009 Hs 326108 ESTs 27
405523 27
434849 AW292765 Hs 8053 ESTs 27
452755 AW138937 Hs 213436 ESTs, Weakly similar to A34087 hypotheti 27
438055 AA776655 Hs 270942 ESTs 27
420908 AL049974 Hs 100261 Homo sapienε mRNA, cDNA DKFZp564B222 (fr 27
405738 27
417806 AI867277 Hs 183733 ESTs 27
430698 AA492071 gb ne97b04 s1 NCI CGAP.Kidl Homo εapiens 27
441969 AI733386 Hs 129194 ESTs, Weakly similar to ALU1 HUMAN ALU S 27
446092 N33522 Hs 145894 ESTs 27
456869 BE467912 Hs 154294 discs, large (Drosophila) homolog 1 27
413617 BE155373 Hs 279518 amyloid beta (A4) prxursor-like protein 27
444931 AV652066 Hs 75113 general transcription fxtor II I A 27
412236 AW902583 gb QV3-NN1024-260400-171-f10 NN1024 Homo 27
453264 AA034137 Hs 271955 ESTs 27
438370 AA843242 Hs 48523 ESTs 27
406092 27
454874 AW836407 Hs 270143 extracellular glycoprotein EMILIN 2 prec 27
455880 BE153208 gb PM0-HT0335-050400 007-F10 HT0335 Homo 27
459275 AI808913 Hs 339352 Homo sapienε brother of CDO (BOC) mRNA, 27 411987 AA375975 Hs 183380 ESTs Moderately similar to ALU8.HUMAN A 27
441884 AW172630 Hs 144884 ESTs 27
416211 R14625 gb yg45c03 r1 Soares infant brain 1NIB H 27
433128 AB021923 Hs 23367 EST YD1 protein 27
452259 AA317439 Hs 28707 signal sequence receptor gamma (translo 27
453696 AI989482 Hs 146286 kinesm family member 13A 27
456208 AW298698 Hs 334625 Homo sapienε cDNA FLJ14890 fis clone PL 27
425876 AW005887 Hs 234058 ESTs 27
450458 AA009926 gb zι07e05 r1 Soares_fetalJιver_spleen_ 27
406603 27
410181 AI468210 Hs 261285 pleiotropic regulator 1 (PRL1 Arabidops 27
410871 D78367 Hs 66739 keratin 12 (Meeε ann corneal dystrophy) 27
412706 R97106 Hs 167546 ESTs 27
422897 AA679784 Hs 4290 ESTε 27
436329 AI798750 Hs 163960 Homo εapieπs heat shock transcnption fa 27
436679 AI127483 Hs 120451 ESTs Weakly similar to unnamed protein 27
455992 BE179015 gb RC3 HT0612 080500 013- O HT0612 Homo 27
452594 AU076405 Hs 29981 solute earner family 26 (sulfate transp 27
419296 AA236115 Hs 120785 ESTs 27
454747 AW818535 gb RC1 ST0278 140300 016405 ST0278 Homo 27
455791 BE090689 gb RC1 BT0720 280300 011 f08 BT0720 Homo 27
411409 AW844803 gb RC3-CN0056 170300 015 f08 CN0056 Homo 27
426662 AA879474 Hs 122710 ESTs 27
400268 27
438782 AA828380 Hs 126733 ESTs 27
443764 F23283 gb HSPD22980 HM3 Homo sapiens cDNA clone 27
412486 AF210650 Hs 150858 NAG19 protein 27
411514 AW850178 gb IL3 CT0219-271099 022 H12 CT0219 Homo 27
457900 AW976692 Hs 291665 ESTs 27
417376 AA253314 Hs 154103 UM protein (similar to rat protein kma 27
426682 AV660038 Hs 2056 UDP glycosyltransferase 1 family polype 27
435608 AW183971 Hs 250896 ESTs 27
413627 BE182082 Hs 246973 ESTs 27
432415 T16971 Hs 289014 ESTs Weakly similar to A43932 mucin 2 p 27
445660 AI702668 Hs 201955 ESTs 27
441396 AW293677 Hs 186890 ESTs 26
452046 AB018345 Hs 27657 KIAA0802 protein 26
454936 AW846082 gb MR3-CT0176-081099 002-d01 CT0176 Homo 26
454434 AA083558 Hs 261286 ESTs 26
436888 AI942357 Hs 187870 ESTε 26
431613 AA018515 Hs 264482 Homo εapiens mRNA cDNA DKFZp761A0411 (f 26
408812 BE397160 Hs 254763 ESTs Weakly similar to A42442 integπn 26
416690 H84078 Hs 108551 ESTs 26
436471 AA719813 Hs 117662 ESTs 26
425659 AK000590 Hs 158836 hypothetical protein FLJ20583 26
426237 AK001104 Hs 168241 hypothetical protein FLJ10242 26
458257 U48351 Hs 201219 ESTs Weakly similar to S18946 ultra hig 26
455544 AW993880 gb RC3-BN0034-240400-017 d09 BN0034 Homo 26
407494 U10072 gb Human forkhead family (AFX1) mRNA pa 26
452821 AW471181 Hε 160874 ESTs 26
434222 AF119886 Hs 283941 Homo sapiens PR02591 mRNA complete eds 26
429864 AA460039 Hs 286 πbosomal protein L4 26
456273 AF154846 Hs 1148 zinc finger protein 26
402603 26
411162 AW819944 gb QV0-ST0294-240300 172 e03 ST0294 Homo 26
420621 AA278808 gb zs79c09 r1 NCI CGAP GCB1 Homo sapiens 26
435113 AA665469 Hε 117136 ESTs 26
438188 AA779975 Hs 128859 ESTs 26
438295 AI394151 Hs 37932 ESTs 26
450181 H05254 Hs 201198 ESTs 26
433764 AW753676 Hs 39982 ESTs 26
433229 AB040925 Hs 91625 KIAA1492 protein 26
443718 AI083580 Hs 221373 ESTε 26
418246 AI472179 Hs 121276 ESTε Weakly similar to R5HU7A πbosomal 26
453930 AA419466 Hs 36727 hypothetical protein FLJ10903 26
400365 Y10259 Hs 274501 H sapienε ACTH rxeptor mRNA 3 UTR 26
419318 AW969742 Hs 291005 ESTs 26
428527 AI902398 Hs 34492 Cyt19 protein 26
404414 26
446444 AI743737 Hs 24370 ESTs 26
411354 AW992424 Hs 288141 hypothetical protein MGC3156 26
417918 AA209205 Hs 163754 hypothetical protein FLJ12606 26
418310 AA814100 Hs 86693 ESTs 26
454481 AW794878 Hs 314230 ESTs Highly similar to clxk [H εapieπε 26
,441216 BE299830 Hs 192908 ESTs 26
438257 AW474419 Hs 224794 ESTs 26
442264 AI278777 Hs 263455 ESTs Weakly similar to ALULHUMAN ALU S 26
419505 AA243660 Hs 143061 ESTs 26
417596 R07343 Hs 226823 ESTs Moderately similar to I54374 gene 26
443555 N71710 Hs 21398 ESTε Moderately similar to A Cham A H 26
444517 AI939339 Hs 146883 ESTs 26
454867 AW835924 gb PM1 LT0018-250200 002 e09 LT0018 Homo 26
455870 AW452631 Hs 313803 ESTs Highly similar to AF157833 1 noncl 26 457630 AI680803 Hs 112627 ESTs 26
424210 T71397 Hs 222707 KIAA1718 protein 26
447748 AI422023 Hs 161338 ESTs 26
411970 AA099142 Hs 13804 hypothetical protem dJ4620232 26
441233 AA972965 Hs 135568 ESTs 26
400706 26
436033 H75391 Hs 255748 ESTs 26
440836 AW370882 Hs 222080 ESTs 26
431086 AI829692 Hs 211561 ESTs 26
455110 BE154505 gb PMO HT0343 281299003 e06 HT0343 Homo 26
455678 BE066007 gb RC3-BT0319 120200014-d09 BT0319 Homo 26
413088 BE064962 gb RC1-BT0313-130400 016-c02 BT0313 Homo 26
436196 AK001084 Hs 333498 Homo sapiens cDNA FLJ10222 fis, clone HE 26
437396 BE140396 Hs 21621 hypothetical protein DKFZp762O076 26
432374 W68815 Hs 301885 Homo sapiens cDNA FLJ 11346 fis, clone PL 26
442690 AI014727 Hs 160047 ESTs, Weakly similar to B28096 lιπe-1 pr 26
441700 AA233556 Hs 126908 hypothetical protein FLJ12994 26
410286 AI739159 Hs 61898 DKFZP586N2124 protein 26
403271 26
429761 AI276780 Hs 135173 ESTs 26
437085 AA743935 Hs 202329 ESTs 26
450822 AW771860 Hs 205130 ESTs 26
457506 AF131757 Hs 274533 Homo sapiens clone 24926 mRNA sequence 26
416585 X54162 Hs 79386 leiomodm 1 (smooth muscle) 26
430357 AW976789 Hs 165607 ESTs 26
417249 N58198 Hs 182898 ESTs 26
423554 M90516 Hs 1674 glutamine fructose-6-pfιosphate transamm 26
440400 AA994364 Hs 125594 ESTε, Weakly similar to T25472 hypotheti 26
440460 H92571 Hs 234478 Homo sapiens cDNA FLJ22648 fis, clone H 26
446302 AI285848 Hs 149757 ESTs 26
424012 AW368377 Hs 137569 tumor protein 63 kDa with εtrong homolog 26
428944 AA780181 Hs 41182 Homo εapiens DC47 mRNA, complete eds 26
419647 AA348947 Hs 91816 hypothetical protein 26
455500 AW963582 gb EST375655 MAGE resequences, MAGH Homo 26
419435 AI200540 Hs 14877 ESTs, Weakly similar to (defline not ava 26
452450 AW854891 Hs 194720 ATP-biπdmg casεette, sub-family G (WHIT 26
434699 AA643687 Hs 149425 Homo sapiens cDNA FLJ11980 fis, clone HE 26
436421 AI678031 Hs 122813 ESTs, Weakly similar to ZN22_HUMAN ZINC 26
447505 AL049266 Hs 18724 Homo sapiens mRNA, cDNA DKFZp564F093 (fr 26
419758 U31973 Hε 93173 phosphodiesterase 6C, cGMP-spxific, con 26
426698 AA394104 Hs 97489 ESTs 26
446861 AI696519 Hs 14427 Homo sapiens cDNA FLJ21800 fis, clone H 26
423025 AA831267 Hs 12244 hypothetical protein FU20097 25
447624 AI640326 Hs 62713 ESTs 25
411736 AW859089 gb MR1-CT0350-150200 002-d02 CT0350 Homo 25
416334 H53139 Hs 36271 ESTε 25
446818 AI342668 Hs 279765 ESTε 25
454836 AW833711 gb QV4-TT0008 251199-043-e11 TT0008 Homo 25
442278 AI733477 Hs 166313 ESTε 25
453393 AW956392 Hs 110376 ESTs 25
420854 AW296927 gb Ul-H BWO-ajc-c-07-O-UI s1 NCI CGAP.Su 25
408729 AA195764 Hs 72639 ESTs 25
455675 BE065984 gb RC3-BT0319-120200-01 -a06 BT0319 Homo 25
411660 AW855718 gb RC1-CT0279-070100021-a06 CT0279 Homo 25
455252 AW876627 gb RC3-PT0028-120200-013-d11 PT0028 Homo 25
409156 N76186 Hs 173518 M-phase phoεphoprotem homolog 25
423175 W27595 Hs 18653 hypothetical protein FLJ14627 25
430291 AV660345 Hs 238126 CGI-49 protein 25
401785 25
402369 25
439079 AF085937 Hs 38348 ESTε 25
412566 AW962574 gb EST374647 MAGE reεequeπceε, MAGG Homo 25
411463 AW847645 gb IL3-CT0213-280100-056-A04 CT0213 Homo 25
413758 BE162391 gb PM2-HT0451-090100-002404 HT0451 Homo 25
404988 25
409446 AI561173 Hs 67688 ESTε 25
412613 AA653507 Hs 285711 hypothetical protein FLJ13089 25
417909 R35614 gb yg66e08 r1 Soares infant brain 1NIB H 25
454743 AW818456 Hs 79347 KIAA0211 gene product 25
406364 25
404108 25
411934 AW876538 gb RC3 PT0028-190100-012-b06 PT0028 Homo 25
415747 AA381209 gb EST94257 Activated T-cells I Homo sap 25
443526 AW792804 Hs 134002 ESTs 25
415319 AA659823 Hs 34955 Homo sapiens cDNA FLJ 13485 fis, clone PL 25
454864 AW835775 gb QV4-LT0016-240200-110-d04 LT0016 Homo 25
458771 AW295151 Hs 163612 ESTs 25
414349 BE512968 gb 601172296F1 NIH.MGC.15 Homo sapiens c 25
426589 AW954460 gb EST366530 MAGE resequences, MAGC Homo 25
429515 AL031228 Hs 204370 DNA segment on chromosome 6 (unique, pse 25
443614 AV655386 Hs 7645 fibnnogeπ, B beta polypeptide 25
411772 BE170301 gb QV4-HT0536 040500-193405 HT0536 Homo 25
434784 AA649051 Hs 164007 ESTs 25 429322 D86984 Hs 199243 KIAA0231 protein 25
446252 AI283125 Hs 150009 ESTs 25
453361 AA035197 Hε 107375 ESTs 25
455275 AW977806 gb EST389810 MAGE resequences, MAGO Homo 25
449410 AA001356 Hs 18159 ESTs 25
451403 AA885569 Hs 40919 Homo sapiens cDNA FLJ14511 fis, clone NT 25
458861 AI630223 gb ad06g08 r1 Proliferating Erythroid Ce 25
416944 N22809 gb yw41e07 s1 Weizmann Olfactory Epithel 25
423010 W25436 Hs 90725 ESTs, Moderately similar to I38022 hypot 25
412505 AA974491 Hs 21734 ESTs 25
446399 AI298405 Hs 150080 ESTs 25
412139 BE044976 gb hn25b10 x1 NCI_CGAP_Thy7 Homo sapiens 25
403691 25
424025 AI701852 Hs 301296 Homo sapiens cDNA FLJ23131 fis, clone L 25
420352 BE258835 gb 601117374F1 NIH_MGC_16 Homo sapiens c 25
422342 AA309272 gb EST180209 Liver, hepatocellular carci 25
447343 AA256641 Hs 236894 ESTs, Highly similar to S02392 alpha-2-m 25
457770 BE065030 Hs 124179 ESTs 25
427731 AA411750 Hs 20943 ESTs 25
426920 AA393351 Hs 132121 ESTs 25
427794 AA709186 Hs 282963 ESTs 25
429903 AL134197 Hs 93597 cyclm-dependent k ase 5, regulatory su 25
454190 AW177821 gb IL3-HT0059-180899007-C05 HT0059 Homo 25
414550 BE379808 gb 601159567T1 NIH MGC 53 Homo sapiens c 25
436391 AJ227892 Hs 146274 ESTs 25
401989 25
423346 AI267677 Hs 127416 synaptojanin 1 25
444905 AW135863 Hs 209228 ESTs 25
424539 L02911 Hs 150402 activin A receptor, type I 25
400861 25
458426 AI084514 Hs 249587 ESTs 25
429520 AA160142 Hs 205058 hypothetical protem FLJ20075 25
403568 25
430692 X80240 gb H sapiens endogenous retrovirus HERV- 25
451078 AI927694 Hs 204470 ESTs 25
424560 AA158727 Hs 150555 protein predicted by clone 23733 25
427888 AA417088 Hs 137598 ESTs 25
425541 AA359119 gb EST68172 Fetal lung II Homo sapienε c 25
422840 U44059 Hs 121481 thyrotrophic embryonic factor 25
404708 25
405008 25
453772 BE281431 Hs 16323 Homo sapiens, Similar to G antigen 8, cl 25
411036 AA857218 Hs 297007 membrane bound transcnption factor prot 25
444575 AI264847 Hs 22545 Homo sapiens cD A FLJ 12935 fis, clone NT 25
449311 AI657014 gb tt49a12 1 NCI CGAP GC6 Homo sapienε 25
454277 AW295069 Hs 31743 ESTs, Weakly similar to Z157 HUMAN ZINC 25
454566 AW807605 gb R4-ST0098-120100-001-b06 ST0098 Homo 25
454597 AW809648 gb R4-ST0124-261099-015- 01 ST0124 Homo 25
416208 AW291168 Hs 41295 ESTs, Weakly similar to MUC2.HUMAN MUCIN 24
407851 NM 014496 Hs 40434 nbosomal protein S6 kinase, 90kD, polyp 24
446554 AA151730 Hs 301789 nudix (nucleoside diphosphate linked oi 24
452850 H23230 Hs 22481 ESTs, Moderately similar to A46010 X-lin 24
406468 24
407300 AA102616 gb zπ43e07 s1 Stratagene HeLa cell s393 24
408617 R61736 Hs 124128 ESTs 24
409627 AW997628 Hs 313637 ESTs 24
416665 H72974 gb yu28a10 s1 Soares fetal liver spleen 24
417404 NM 007350 Hs 82101 plxkstnn homology-like domain, family 24
418994 AA296520 Hs 89546 selectiπ E (endothelial adhesion molxul 24
428709 BE268717 Hs 104916 hypothetical protein FLJ21940 24
429654 AI435046 Hs 164318 ESTs 24
432253 AW090822 Hs 274174 transcnption elongation factor (Sill) e 24
439786 AV652707 Hs 33756 Homo sapiens mRNA full length insert cDN 24
445432 AV653771 gb AV653771 GLC Homo sapiens cDNA clone 24
453052 R63050 Hs 223813 ESTs 24
454137 AW500340 Hs 313876 ESTs, Weakly similar to I38022 hypotheti 24
459608 AL119471 gb DKFZp761M141 r1 761 (synonym hamy2) 24
452843 AI796769 Hs 208320 ESTs 24
433222 AW514472 Hs 238415 ESTε, Moderately similar to ALU8 HUMAN A 24
449695 AA164569 Hs 34550 ESTs 24
431532 AI537817 Hs 270311 ESTε, Weakly similar to ALULHUMAN ALU S 24
425967 NM 007159 Hs 4007 Sarcolemmal-assxiated protein 24
400641 24
430982 R17432 Hε 22217 Homo sapienε clone IMAGE 32106, mRNA seq 24
432808 NM 015985 Hs 278973 angiopoietm 3 24
410845 AW807182 gb MR4-ST0062-180200 001-b04 ST0062 Homo 24
411561 H81164 Hs 285017 hypothetical protein FLJ 21799 24
421083 AA283628 Hs 298016 ESTs, Weakly similar to 138022 hypotheti 24
423513 AF035960 Hs 129719 transglutaminase 5 24
434627 AI221894 Hs 39311 ESTs 24
435663 AI023707 Hs 134273 ESTs 24
455879 BE153275 gb PMO-HT0335-180400-008-e11 HT0335 Homo 24
451797 AW663858 Hs 333513 small inducible cytokine subfamily E, me 24 409041 AB033025 Hs 50081 KIAA1199 protein 24
423244 AL039379 Hs 209602 ESTs, Weakly similar to ubiquitous TPR m 24
453874 AW591783 Hs 36131 collagen, type XIV, alpha 1 (undulin) 24
448889 BE140902 gb IL1 HT0028240699001-C11 HT0028 Homo 24
439481 AF086294 Hs 125844 ESTs 24
412074 S74683 Hs 73139 ADP-πbosyltraπsferase 1 24
403053 R58624 Hs 2186 eukaryotic translation elongation factor 24
409298 AA070211 gb zm68c04 s1 Stratageπe neuroepithelium 24
411322 AW887330 Hs 172405 cell division cycle 27 24
447640 AI417187 gb tg75g11 x1 Soares_NhHMPu_S1 Homo εapi 24
447849 AI538147 Hs 164277 ESTε 24
458763 AI693417 Hs 293309 ESTs 24
404638 24
413986 Z43567 gb HSC1FC021 normalized infant brain cDN 24
407721 Y12735 Hs 38018 dual-specificity tyrosιne-(Y) phosphoryl 24
422321 AA906427 Hs 181035 hypothetical protein MGC11296 24
408238 W95901 gb ze43d11 r1 Soares retina N2b4HR Homo 24
436747 AW977192 Hs 291343 ESTs 24
437048 AA743240 Hs 91582 ESTs 24
413143 BE067232 gb PM3 BT0347-170200 001-b05 BT0347 Homo 24
404561 24
444009 AI380792 Hs 135104 ESTε 24
400250 24
403891 24
417002 T79613 Hs 14613 ESTs 24
439446 AI927629 Hs 57873 ESTs 24
441227 AW295407 Hs 128893 ESTs 24
445038 AI635444 Hs 143917 dJ467N11 1 protein 24
455107 BE154113 gb PM1-HT0340-151299 003 a08 HT0340 Homo 24
458624 AI362790 Hs 278639 KIAA1684 protein, likely homolog of mouε 24
459344 AW499533 Hs 257976 ESTs 24
452605 AW968557 Hs 90012 hypothetical protein FLJ23441 24
457652 AF116656 Hs 273809 Homo sapiens PR01167 mRNA, complete eds 24
450068 AW207212 Hs 280925 ESTs 24
444750 AW242684 Hs 243623 ESTs 24
414591 AI888490 Hs 55902 ESTs, Weakly similar to ALU8_HUMAN ALU S 24
407264 L34727 gb Homo sapienε T-cell receptor beta (TC 24
443169 AI038687 Hs 133338 ESTs 24
426536 AI949749 Hs 44441 ESTs 24
449752 AI668626 Hs 61773 Homo sapiens cDNA FLJ 11648 fis, clone HE 24
459592 AL037421 Hs 208746 ESTs, Moderately similar to pot ORF I [ 24
429504 X99133 Hs 204238 hpocalin 2 (oncogene 24p3) 24
429063 AW363845 Hs 122142 ESTs, Weakly similar to A46010 X-linked 24
430484 D82880 Hs 241548 RAS p21 protein xtivator 2 24
423673 BE003054 Hs 1695 matrix metalloproteinase 12 (mxrophage 24
447375 AI376660 Hs 257822 ESTε 24
444230 H95537 Hs 146067 ESTs 24
439911 AA854024 Hs 189110 ESTs 24
421296 NM_002666 Hs 103253 peπlipm 24
449385 AI650471 Hs 270370 ESTs 24
430044 AA464510 Hs 152812 ESTs 24
427131 AA448460 Hs 112017 GE36 gene 24
409103 AF251237 Hs 112208 XAGE-1 protein 24
421354 AA766485 Hs 269664 ESTs 24
423740 Y07701 Hs 293007 aminopeptidase puromycin sensitive 24
440048 AA897461 Hs 328737 ESTs, Weakly similar to envelope protein 24
441358 AW173212 Hs 129041 ESTs 24
453857 AL080235 Hs 35861 DKFZP586E1621 protein 24
414290 AI568801 Hs 71721 ESTs 24
427342 AL110150 Hs 176680 Homo sapiens mRNA, cDNA DKFZp586D0724 (f 24
459459 AA460445 gb zx66h11 r1 Soares_total_fetus_Nb2HF8_ 24
434638 H50758 gb yp86e06 r1 Soares fetal liver spleen 24
442717 R88362 Hs 180591 ESTs, Weakly similar to T23976 hypotheti 24
419637 W27493 gb 31h10 Human retina cDNA randomly pπm 24
431169 AW971240 gb EST383329 MAGE resequences, MAGL Homo 24
449432 AW451361 Hs 196529 ESTs 24
458734 AI554946 Hs 158794 ESTs 24
449529 AI990559 Hs 232033 ESTs 24
426088 AF038007 Hs 166196 ATPase, Class I, type 8B, member 1 24
420195 N44348 Hs 26243 Homo sapienε cDNA FLJ 11177 fis, clone PL 24
418105 AW937488 Hs 178000 ESTs, Weakly similar to FV1 MOUSE FRIEND 24
430957 AI937072 Hs 55043 Homo sapiens cDNA FLJ 13277 fis, clone OV 24
418188 AW139413 Hs 151880 ESTs 24
424103 NM 001918 Hs 139410 dihydrolipoamide branched chain fransacy 24
454324 AW608930 Hs 52184 hypothetical protein FLJ20618 24
437369 AA765230 Hs 121742 ESTs 24
453211 W84829 gb zh53f04 r1 Soares_fetal_lιver_εpleen_ 24
451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 24
400462 24
413697 AA131315 Hs 47144 DKFZP586N0819 protein 24
421755 AW169454 Hs 207422 ESTs, Weakly similar to S71949 metallopr 24
424195 U50536 Hs 142907 Human BRCA2 region, mRNA sequence CG011 24
434163 AW974720 Hs 25206 group XII secreted phospholipase A2 24 435985 AA703154 Hs 191934 ESTs 24
449916 T60525 Hs 299221 pyruvate dehydrogenase kinase, isoenzyme 24
458661 AI299789 Hs 166999 ESTs, Moderately similar to I38344 Mm 24
459023 AW968226 Hs 60798 ESTs 24
406005 24
456561 AI868634 Hs 246358 ESTs, Weakly similar to T32250 hypotheti 24
452161 R43077 Hs 221747 ESTs 24
436590 AI393115 Hs 127655 ESTs 24
430151 AW968203 gb EST380398 MAGE resequences, MAGJ Homo 24
445635 AI769774 Hs 209831 ESTs, Weakly similar to ALU1 HUMAN ALU S 24
433479 AW511459 Hs 249972 ESTs 24
441676 BE564206 Hs 49889 ESTs 24
407965 W21483 Hs 41707 heat shock 27kD protein 3 24
450682 Z42993 Hs 25320 Homo sapienε clone 25142 mRNA εequence 24
452958 AA883929 Hs 40527 ESTε 24
454032 W31790 Hs 194293 ESTs Weakly similar to I54374 gene NF2 24
405347 24
440577 AA889945 Hs 326381 EST 24
455780 BE088828 gb CM2-BT0693-230300-129 g09 BT0693 Homo 24
457024 AA397546 Hs 119151 ESTε 24
404249 24
437511 AI807500 Hs 125247 ESTε 24
421338 AA287443 gb zε52o10 r1 NCI.CGAP.GCB1 Homo sapiens 24
425146 AW954627 gb EST366697 MAGE resequences, MAGC Homo 24
428277 AA425220 Hs 179203 ESTs 24
444870 AI200621 Hs 148504 ESTs 24
402090 24
458507 AI185703 Hs 206957 ESTs 24
443054 AI745185 Hs 8939 yes-aεsociated protein 65 kDa 24
446534 AI307356 Hs 175225 ESTs 24
453111 AB014598 Hs 31720 hephaestm 24
405230 24
405935 24
413642 BE154837 gb PM1-HT0345 121199 001-c08 HT0345 Homo 24
420724 AA279694 Hs 191540 ESTs 24
436998 AA745625 Hs 291414 ESTs, Weakly εimilar to ALU8.HUMAN ALU S 24
445748 U80766 Hs 13252 Human EST clone 22453 mariner transposon 24
434283 AW235341 Hs 58715 thiamine pyrophosphokmase 23
407404 AF040257 gb Homo sapiens TNF rxeptor homolog mRN 23
440621 AW296024 Hs 150434 ESTs 23
423417 AP000365 Hs 128342 potassium large conductance calcium-xti 23
424131 AA335714 Hs 199665 ESTs 23
450737 AW007152 Hs 203330 ESTs 23
453687 T55674 Hs 283108 hemoglobin, gamma G 23
442704 AI015463 Hs 130987 ESTs 23
457756 AA126136 Hs 38125 iπterferon-induced protein 75, 52kD 23
412732 AW993300 gb RC2-BN0033-180200 015-g06 BN0033 Homo 23
418998 F13215 Hs 287849 ESTs, Weakly similar to T22074 hypotheti 23
419751 AW195581 Hs 93121 KIAA0761 protein 23
429485 AW197086 Hs 99338 ESTs 23
433377 AI752713 Hs 43845 ESTs 23
434896 AW022054 Hs 136591 ESTs 23
441675 AI914329 Hs 5461 ESTs 23
444711 AI188739 Hs 148488 ESTs 23
445621 AI733818 Hs 145549 ESTs 23
449182 AW292381 Hs 224150 ESTs 23
430987 Y08564 Hs 248190 UDP-N-xetyl-alpha-D-galxtosamme polyp 23
404068 23
414366 BE549143 gb 601076456F1 NIH MGC 12 Homo εapiens c 23
438315 R56795 Hs 82419 ESTs 23
423161 AL049227 Hs 124776 Homo sapiens mRNA, cDNA DKFZp564N1116 (f 23
447998 AI768289 Hs 304389 ESTs 23
410150 AW382942 Hs 6774 ESTs 23
432792 AA448114 Hs 278950 protxadheπn beta 1 23
443363 AI792629 Hε 133293 ESTs 23
440729 AA904739 Hs 128204 ESTs 23
411045 AW854691 Hε 115325 RAB7, member RAS oncogene family-like 1 23
459207 AW138410 Hs 45051 ESTs 23
459124 AW301478 Hs 184592 protein kinase, lysine deficient 1 23
458684 BE281115 Hs 98855 hypothetical protein FLJ20909 23
427962 AA946582 Hs 8700 deleted in liver cancer 1 23
401899 23
432116 AA902953 Hs 308538 ESTs 23
404196 23
410999 AW813004 gb RC3-ST0186 230300 019 h02 ST0186 Homo 23
413308 W28131 gb 42f7 Human retina cDNA randomly prime 23
430264 AA470519 gb nc71f10 ε1 NCI CGAP Pr1 Homo εapiens 23
443482 AW188093 Hs 250385 ESTs 23
453305 R39224 Hs 267997 EHM2 ene 23
451963 AI825440 Hs 224952 ESTs 23
453043 AW136440 Hs 224277 ESTs 23
435559 AF209198 Hs 42636 zinc finger protein 277 23
440727 AI073991 Hs 134268 ESTε, Weakly similar to 2109260A B cell 23 434120 AI436050 Hs 143937 ESTs 23
429768 AA805719 Hs 192154 ESTs 23
425292 NM 005824 Hs 155545 37 kDa leucine πch repeat (LRR) protein 23
455841 BE145836 gb MRO HT0208 101299-202-b08 HT0208 Homo 23
411093 BE067650 gb MR4-BT0358 090300 003 e01 BT0358 Homo 23
430706 NM 003540 Hs 247816 H4 histone family, member C 23
428268 AA424957 Hs 294132 ESTs 23
458833 AW236702 Hs 171431 ESTs, Weakly similar to A46010 X linked 23
452215 AK002043 Hs 28472 hypothetical protein FLJ11181 23
444109 AH 24553 Hs 48965 Homo sapiens cDNA FLJ21693 fis clone C 23
428411 AW291464 Hs 10338 ESTε 23
433098 AW180593 Hs 151143 ESTε 23
424882 AI379461 Hs 153636 far upstream element (FUSE) binding prot 23
453178 AA496086 Hs 61648 ESTs 23
404569 23
413841 M34276 Hε 75576 plasminogen 23
424068 U50531 Hs 138751 Human BRCA2 region, mRNA sequence CG030 23
433532 AW975367 gb EST387475 MAGE resequences MAGN Homo 23
442710 AI015631 Hs 23210 ESTs 23
444206 AW301017 Hs 146492 ESTs 23
451264 AI768235 gb wg82g08 x1 Soares_NSF_F8 9W_OT_PA_P_S 23
454784 AW820626 gb RCO ST0299 190100 012 e10 ST0299 Homo 23
429080 AA446228 Hs 99057 ESTs 23
404166 23
416327 R99822 Hs 36172 ESTs 23
400631 AF173937 Hs 109494 secreted protein of unknown function 23
438504 AW665281 Hs 224625 ESTε 23
435325 AI038388 Hs 119309 ESTε 23
421253 AI188102 Hs 31028 ESTs 23
427046 BE246180 Hs 121385 ESTs 23
432711 AA563785 Hε 152465 ESTs, Weakly similar to I38022 hypotheti 23
439715 AA524504 Hs 42612 ESTs, Weakly similar to ALULHUMAN ALU S 23
441398 AA932398 Hs 292036 ESTs Weakly similar to B34087 hypotheti 23
448458 AW614367 Hs 171054 ESTs 23
452542 AW812256 gb RCO ST0174-191099 031-a07 ST0174 Homo 23
417768 R24732 Hs 175139 ESTs 23
427374 AH 50033 Hs 143686 ESTs 23
446847 T51454 Hs 82845 Homo sapiens cDNA FLJ21930 fis, clone H 23
423600 AI633559 Hs 310359 ESTs 23
413006 W03857 Hs 34298 ESTs 23
434698 BE044674 gb hm46f02 x1 NCI CGAP RDF1 Homo εapienε 23
407639 AW205369 Hs 312830 ESTε 23
455121 BE156459 gb QV0-HT0368 040100 082406 HT0368 Homo 23
448117 H49129 Hs 172982 ESTε 23
443931 H23213 Hs 22657 ESTs 23
450795 AW173371 Hs 60435 ESTs 23
418632 AW118745 Hs 9460 Homo sapiens mRNA cDNA DKFZp547C244 (fr 23
419441 AW023731 Hs 274368 MSTP032 protein 23
455067 ' AW854538 gb RC3-CT0255-200100-024-b02 CT0255 Homo 23
418291 BE300369 Hs 289038 hypothetical protein MGC4126 23
455964 BE166924 gb CM4-HT0501-240300-519 f01 HT0501 Homo 23
445944 H06336 Hs 13480 Homo sapiens clone 24875 mRNA sequence 23
424827 AI057094 Hs 96867 Homo sapiens cDNA FLJ23155 fis, clone L 23
449272 AW137656 Hs 197645 ESTs 23
445292 AV653264 Hs 13982 Homo sapiens cDNA FLJ14666 fiε, clone NT 23
415131 D61119 gb HUM158C11B Clontech human fetal brain 23
444715 AV650947 Hs 282464 ESTε 23
439560 BE565647 Hs 74899 hypothetical protein FLJ 12820 23
444140 AV648089 Hs 282383 ESTε 23
423949 AI014546 Hs 130912 ESTε 23
428434 AW363590 Hs 65551 Homo εapienε, Similar to DNA εegment, Ch 23
445711 T79611 Hs 193691 ESTs 23
424565 AW102723 Hs 75295 guanylate cyclase 1, soluble, alpha 3 23
455201 AW947884 gb PM1 MT0010-200300 001-g08 MT0010 Homo 23
429180 AA806287 Hs 58893 ESTs 23
418849 AW474547 Hs 53565 Homo sapiens PIG-M mRNA for mannosyltran 23
425523 AB007948 Hs 158244 KIAA0479 protein 23
416509 N57713 Hs 260899 ESTs, Moderately similar to ZN91 HUMAN Z 23
419337 AW291112 Hs 209978 ESTs 23
419699 AA248998 Hs 173044 ESTs, Weakly similar to 138022 hypotheti 23
428976 AL037824 Hs 194695 ras homolog gene family, member 1 23
436294 AA708310 gb zg07b07 s1 Soareε.pmeal _gland_N3HPG 23
458925 R15891 Hs 281587 Human (clone CTG-A4) mRNA εequeπce 23
433939 AL133887 Hs 254122 hypothetical protein 23
450048 AI693269 Hs 202273 ESTs 23
451640 AA195601 Hs 26771 Human DNA sequence from clone 747H23 on 23
416677 T83470 Hs 334840 ESTs Moderately similar to 178885 seπn 23
405920 23
405747 23
412105 H07971 Hs 94319 VPS10 domain receptor protein 23
420457 AA482280 Hs 191656 ESTs 23
407726 AA435679 Hs 88594 ESTs 23
423720 AL044191 Hs 23388 hypothetical protein DKFZp434F0318 23 409517 X90780 Hs 120036 troponin I cardix 23
435352 AI056599 Hs 120893 ESTs 2 3
439871 R88518 Hs 46736 hypothetical protein FLJ23476 23
444098 AV647969 Hs 109694 KIAA1451 protein 23
449276 AW241510 Hs 252713 ESTs 23
417712 AA205569 Hs 194193 ESTs, Moderately similar to ALULHUMAN A 23
449015 AL038958 Hs 22868 protein tyrosine phosphatase non recept 23
411377 AW841462 gb RC6 CN0014-080300 012-B09 CN0014 Homo 23
429276 AF056085 Hs 198612 G protein-coupled rxeptor 51 23
411816 AW864609 gb PM3 SN0017 240300 001 h03 SN0017 Homo 23
455280 AW886156 gb RC5 OT0078-150300 021-E08 OT0078 Homo 23
407809 AW082279 Hs 244106 ESTs 23
420478 AA521259 Hs 193796 ESTs 23
424073 U03493 Hs 138959 gap junction protein alpha 7, 45kD (con 2 3
445117 AI208754 Hs 147369 ESTs 23
459390 BE385725 gb 601276347F1 NIH_MGC_20 Homo sapiens c 2 2
420230 AL034344 Hs 284186 forkhead box C1 22
411517 AW850267 gb IL3-CT0219 161199031-A09 CT0219 Homo 22
403678 2 2
457003 S78234 Hs 172405 cell division cycle 27 22
404531 Z25884 Hs 121483 chloride channel 1 , skeletal muscle (Th 2 2
423045 AW967472 Hs 183302 PCTAIRE protein kinase 2 22
409427 AW389668 gb RC2 ST0168 071299 013406 ST0168 Homo 2 2
434745 AW974445 Hs 185155 ESTs Weakly similar to T12482 hypotheti 22
400696 2 2
407259 L02256 gb Human Fab fragment binding syncytial 2 2
411893 R82845 Hs 273789 ESTs 22
428192 AA424051 Hs 304742 ESTε 2 2
435634 T82384 gb yc14f05 r1 Stratagene lung (937210) H 22
438018 AK001160 Hε 5999 hypothetical protein FLJ10298 2 2
458303 AI264628 Hε 125428 ESTs 22
405692 2 2
403572 2 2
415380 F07953 Hs 16085 putative G-protein coupled receptor 2 2
433014 NM 014711 Hs 279912 KIAA0419 gene product 22
417859 T26453 gb AB214F6R Infant brain LLNL array of 22
456472 AK001714 Hs 95744 hypothetical protein similarto ankyπn 22
444106 AI123922 Hs 138215 Homo sapiens cDNA FLJ11400 fis clone HE 2 2
428231 U17989 Hs 183105 nuclear autoantigen 22
454086 AW885909 Hs 6975 PRO1073 protein 22
425071 NM.013989 Hs 154424 deiodmase, lodothyroπine, type II 22
416348 H65887 Hs 272163 ESTs 22
403780 2 2
414262 AW975616 Hs 291469 ESTs 22
419423 D26488 Hs 90315 KIAA0007 protein 22
442078 AW268583 Hs 262629 ESTs 22
452975 M85521 Hs 244482 Homo sapiens clone IMAGE 3611719, mRNA, 2 2
419216 AU076718 Hs 164021 small inducible cytokine subfamily B (Cy 22
416588 H66558 gb yu16e04 r1 Soares fetal liver spleen 22
425368 AB014595 Hs 155976 cullin 4B 22
425686 M73531 Hs 1937 retinal degeneration, slow (retinitis pi 22
441638 AW293202 Hs 133451 ESTs 22
446845 AI343645 Hs 156108 ESTs 22
422563 BE299342 Hs 19348 hypothetical protein FLJ 13119 22
436574 AW293527 Hs 126465 ESTs 22
424584 H10692 Hs 13310 ESTs 2 2
456347 U00803 Hs 89426 fyn-related k ase 22
446901 AI347274 gb tc05d02 x1 NCI_CGAP_Co16 Homo sapiens 22
459364 W69284 gb zd46c03 r1 Soares_fetal_heart_NbHH19W 22
430686 NM 001942 Hs 2633 desmoglein 1 22
414831 M3Ϊ158 Hε 77439 protein kinase, cAMP-dependeπt regulato 22
425707 AF115402 Hs 11713 E74-Iιke fxtor 5 (ets domain transcπpt 2 2
403525 22
453343 AA905353 Hε 121622 ESTs 22
421574 AJ000152 Hs 105924 defensm, beta 2 22
449327 AI638743 Hs 224672 ESTs 22
454769 AW819848 gb QVO-ST0294-070300-151-b04 ST0294 Homo 22
420493 AI635113 Hs 270366 ESTs, Weakly similar to 178885 seππe/th 22
401614 22
404767 22
403534 22
410594 AW770778 Hs 281238 ESTs 22
436193 AA706059 Hs 255286 ESTs 22
439626 N22415 Hs 189080 ESTs 22
456481 AA258033 Hs 108110 DKFZP547E2110 protein 22
441453 AW176106 Hs 285459 ESTs 22
424946 M64572 Hs 153932 protein tyroεine phosphatase, non rxept 2 2
437332 AA814943 gb oc07d06 s1 NCI.CGAP.GCB1 Homo εapienε 22
454419 AA082211 Hs 233936 myosin, light polypeptide regulatory, n 2 2
416225 AA577730 Hs 188684 ESTs Weakly similar to PC4259 ferntin 22
450579 AW136774 Hs 48614 ESTs 2 2
400664 22
447613 AL041057 Hs 33363 DKFZP434N093 protein 22 402689 ,AK001334 Hs 15470 putative nng zinc finger protein NY-REN 22
430884 AF053748 Hs 248114 glial cell derived neurotrophic factor 22
432797 AA565264 Hs 136443 ESTs 22
405608 22
426365 AA376667 Hs 10283 RNA binding motif protein 8B 22
405634 22
423646 H02364 gb yj35d06 r1 Soares placenta Nb2HP Homo 22
434690 AI867679 Hs 148410 ESTs 22
436572 AA723274 Hs 279596 ESTs 22
447044 AF030107 Hs 17165 regulator of G protein signalling 13 22
448828 AI580296 Hs 174782 ESTs, Weakly similar to KIAA1437 protein 22
457802 T78013 Hs 167279 FYVE-finger-containing Rab5 effector pro 22
444585 AW170015 Hs 6594 ESTs 22
433781 AA609379 Hs 192083 ESTs 22
450587 AI828854 Hs 258538 stπalin, calmoduliπ binding protein 22
434077 AF116659 Hs 321151 Homo sapiens PR01412 mRNA, complete eds 22
448756 AI739241 Hs 171480 ESTs 22
430388 AA356923 Hs 240770 nuclear cap binding protein subunit 2, 2 22
454471 AW902125 gb QV0 NN 1022-120500-220-h 12 NN1022 Homo 22
419107 AW085152 Hs 292987 ESTs 22
455114 AW857121 gb RC1-CT0302 040400017-a12 CT0302 Homo 22
416548 H62953 gb yr47f06 r1 Soares fetal liver spleen 22
454117 BE410100 Hs 40368 adaptor-related protein complex 1, sigma 22
456056 AA463550 Hs 337532 ESTs, Weakly similar to A47582 B-cell gr 22
409998 M78345 Hs 98265 KIAA1877 protein 22
422352 AA766296 Hs 99200 ESTs 22
409191 AW818390 Hs 175613 homolog of Xenopus Claspm 22
433919 AA746311 gb oa56d12 r1 NCI_CGAP_GCB1 Homo sapiens 22
455771 BE084820 Hs 186711 hypothetical protein FLJ20070 22
431632 AK000992 Hs 333144 Homo sapiens cDNA FLJ10130 fis, clone HE 22
454716 AW850684 gb IL3 CT0219 160200 063 D12 CT0219 Homo 22
413752 BE161807 gb MR3-HT0446 300300 203-h01 HT0446 Homo 22
458037 AF074982 Hs 226031 ESTs, Highly similarto KIAA0535 pratem 22
434239 AF119910 Hs 283047 hypothetical protein PR02964 22
435133 AJ010482 Hs 31412 Homo sapiens cDNA FLJ11422 fis, clone HE 22
442772 AW503680 Hε 5957 Homo sapiens clone 24416 mRNA sequence 22
400697 22
455685 BE066976 gb PMO-BT0340-211299 003-c12 BT0340 Homo 22
447039 AV661798 Hs 282915 ESTs 22
404593 22
422728 AW937826 Hs 103262 ESTs, Weakly similar to ZN9LHUMAN ZINC 22
421976 AL138443 Hs 23450 mitochondnal ribosomal protein S25 22
401673 22
425001 U55184 Hs 154145 hypothetical protein FLJ 11585 22
447816 NM 007233 Hs 274329 TP53 target gene 1 22
416143 AI955650 Hs 79033 glutaminyl peptide cyclotransferase (glu 22
419118 AA234223 Hs 139204 ESTs 22
426261 AW242243 Hs 168670 peroxisomal farnesylated protein 22
449808 AA694220 Hs 15403 ESTs, Moderately similar to ALU7.HUMAN A 22
454749 AW818649 gb RC1-ST0278-040400-018-e02 ST0278 Homo 22
456933 AA363946 Hs 20969 ESTs 22
402942 22
437064 AI023264 gb ov64h08 s1 Soares_testιs_NHT Homo sap 22
458623 AI305223 Hs 148056 ESTs 22
415257 F03016 Hs 27513 ESTs 22
426269 H15302 Hs 168950 Homo sapiens mRNA, cDNA DKFZp566A1046 (f 22
442783 AI017586 Hs 131181 ESTs 22
444313 AI140494 Hs 197955 KIAA0704 protein 22
453444 AL036531 gb DKFZp564l1162_r1 564 (synonym hfbr2) 22
422757 AI909935 Hs 65551 Homo sapiens, Similarto DNA segment, Ch 22
430013 AA463833 Hs 151275 ESTs, Weakly similar to TRHY HUMAN TRICH 22
437138 AI935622 Hs 271245 ESTs 22
406298 22
409723 AW885757 Hs 257862 ESTs 22
414481 AW451956 Hs 8383 bromodomain adjxent to zinc finger doma 22
433266 AI863224 Hs 31476 Homo sapienε cDNA FLJ13872 fiε, clone TH 22
435090 BE217923 Hs 149595 ESTε 22
457187 AA443927 Hs 144360 EST 22
445061 AI253094 Hs 145227 ESTε 22
442617 AW340093 Hs 130538 ESTε 22
438298 H23542 Hs 181788 ESTs 22
454916 BE067246 gb PM1-BT0348-151299 001-d04 BT0348 Homo 22
428017 AA424983 Hs 98312 ESTε 22
451149 AL047586 Hs 10283 RNA binding motif protein 8B 22
418076 R61388 Hs6724 ESTε 22
403306 NM 006825 Hs 74368 transmembrane protein (63kD), endoplasmi 22
441811 AI073548 Hs 164597 ESTs 22
434763 AA648618 gb ns07a11 r1 NCI.CGAP_Ew1 Homo sapiens 22
447453 AW608645 Hs 18800 hypothetical protein FLJ20281 22
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 22
415424 Z44766 gb HSC28G081 normalized infant brain cDN 22
408332 H91230 Hs 234794 Homo sapiens mRNA, cDNA DKFZp564B083 (fr 22
421216 AV649282 Hs 102664 vesicle associated membrane protein 4 22 429609 AF002246 Hs.210863 cell adhesion molecule with homology to 2.2
448700 BE614182 Hs.123075 ESTs 2.2
457741 BE044740 gb:hm55g10.x1 NCI.CGAP.RDF1 Homo sapiens 2.2
437927 AI039789 Hs.25982 hypothetical protein FLJ21031 2.2
401694 2.2
423531 AW752782 Hs.129750 hypothetical protein FLU 0546 2.2
424419 AK001563 Hs.146589 hypothetical protein FLJ10701 2.2
436640 AA724411 Hs.156065 ESTs 2.2
438290 AA843719 Hs.122341 ESTs 2.2
445908 R13580 Hs.13436 Homo sapiens clone 24425 mRNA sequence 2.2
455735 BE161124 gb:PM0-HT0425-141299-001 -A06 HT0425 Homo 2.2
458455 AV648310 Hs.213488 ESTs 2.2
430680 AW138724 Hs.168974 ESTs, Highly similar to ALU7.HUMAN ALU S 2.2
447147 AA910353 Hs.292815 ESTs, Weakly similar to T23482 hypotheti 2.2
424063 NM 002019 Hs.138671 fms-related tyrosine kinase 1 (vascular 2.2
441874 AA970389 Hs.128055 ESTs 2.2
448045 AJ297436 Hs.20166 prostate stem cell antigen 2.2
433629 R13140 Hs.13359 ESTs 2.2
415266 AA164199 Hs.270152 ESTs 2.2
440633 AI140686 Hs.263320 ESTs 2.2
442789 AW904361 Hs.131191 ESTs, Weakly similar to ALU7.HUMAN ALU S 2.2
417563 AA203701 gb:zx52a10.r1 Soares_fetal_liver_spleen_ 2.2
407788 BE514982 Hs.38991 S100 calcium-binding protein A2 2.2
401240 2.2
408908 BE296227 Hs.250822 seriπe/threonine kinase 15 2.2
411151 AW866497 gb:QV4-SN0024-170400-176-e07 SN0024 Homo 2.2
414275 AW970254 Hs.889 Charat-Leyden crystal protein 2.2
436992 AA741074 Hs.120750 ESTs 2.2
439634 W79377 Hs.167 microtubule-associated protein 2 2.2
411770 NM.014278 Hs.71992 heat shxk protein (frspl 10 family) 2.1
400040 2.1
458762 AW802754 gb:IL2-UM0076-030400-061-H01 UM0076 Homo 2.1
424736 AF230877 Hs.152701 microtubule-interactiπg protein that ass 2.1
419953 BE267154 Hs.125752 ESTs 2.1
410648 AW792909 gb:CMO-UM0001-010300-258-c05 UM0001 Homo 2.1
423717 AA330036 Hs.152003 ESTs 2.1
436683 AW991278 Hs.57787 ESTs 2.1
445225 AI216555 Hs.202398 ESTs 2.1
410991 AW812790 gb:RC3-ST0186-141299-014-g08 ST0186 Homo 2.1
412639 AW961284 Hs.296235 ESTs 2.1
447777 AI424223 gb:te95a05.x1 NCI CGAP Pr28 Homo sapiens 2.1
451270 AW341392 Hs.235795 ESTs 2.1
404526 AI912555 Hs.157195 peptide YY, 2 (seminalplasmin) 2.1
452492 BE063096 gb:CM4-BT0266-091199-039-a02 BT0266 Homo 2.1
417154 AI674701 Hs.21388 ESTε 2.1
428152 AA422030 gb:zv26h05.r1 Soareε NhHMPu S1 Homo sapi 2.1
442312 AI820617 Hs.129216 ESTs, Weakly similar to ALULHUMAN ALU S 2.1
456513 AA279143 Hs.88561 ESTε 2.1
430712 AW044647 Hs.196284 ESTε 2.1
441445 AI221959 Hs.187937 ESTε 2.1
420288 AW071225 Hs.245556 ESTs 2.1
412329 AW937445 gb:QV3-DT0043-090200-080-c09 DT0043 Homo 2.1
447033 AI357412 Hs.157601 ESTs 2.1
436853 BE328074 Hs.148661 ESTs 2.1
455189 AW864176 gb:PMO-SN0014-260400-002-b08 SN0014 Homo 2.1
430899 BE018217 Hs.183528 hypothetical protein FLJ14906 2.1
458356 AI024855 Hs.131575 ESTs 2.1
457040 N77624 Hs.173717 phosphatidic xid phosphataεe type 2B 2.1
424480 AA341442 Hs.205299 ESTs 2.1
403317 U02687 Hs.385 fms-related tyrosine kinaεe 3 2.1
406018 2.1
410566 AA373210 Hs.43047 Homo εapiens cDNA FLJ13585 fis, clone PL 2.1
413801 M62246 Hs.35406 ESTs, Highly similar to unnamed protein 2.1
415871 R55995 Hs.283309 ESTs, Moderately similar to ALULHUMAN A 2.1
416747 AW876523 Hs.15929 hypothetical protein FU12910 2.1
417725 R25257 Hs.21503 ESTs 2.1
424856 AA347746 Hs.9521 ESTs, Weakly similar to ZN43 HUMAN ZINC 2.1
439474 AI824060 Hs.211501 ESTs 2.1
446895 AA166655 Hs.282803 ESTs 2.1
448582 AI538880 Hs.94812 ESTs 2.1
452783 AA028167 Hs.61486 ESTs 2.1
442430 R89164 Hs.48320 double ring-finger protein, Dorfin 2.1
428908 AW303529 Hs.144955 ESTε 2.1
427335 AA448542 Hs.251677 G antigen 7B 2.1
428336 AA503115 Hs.183752 microseminoprotein, beta- 2.1
419290 AI128114 Hs.112885 spinal cord-derived growth factor-B 2.1
416951 AA190926 Hs.190785 ESTs, Moderately similar to S65657 alpha 2.1
439950 AW937417 Hs.293561 ESTs 2.1
458227 Z40670 Hs.181340 ESTs 2.1
447179 AW015633 Hs.157299 ESTs 2.1
454950 AW847460 gb:RC3-CT0208-270999-021-e04 CT0208 Homo 2.1
404453 2.1
420844 AA595522 gb:nh22c09.s1 NCI_CGAP_Pr1 Homo sapiens 2.1 426456 AA580748 Hε 130658 ESTs 2 1
428822 W28418 Hs 30715 potassium voltage gated channel, Isk rel 21
430879 BE149423 Hs 10554 hypothetical protein FLJ12761 21
444584 AI168422 gb ok30e11 x1 Soares_NSF_F8_9W_OT_PA_P_S 21
446296 AA985662 Hs 63131 Homo sapiens cD A FLJ13155 fis, clone NT 21
453853 AL040600 Hs 188083 ESTs 2 1
414083 AL121282 Hs 257786 ESTs 21
401645 2 1
436577 W84774 Hs 17643 ESTs 2 1
427469 AA403084 Hs 269347 ESTs, Weakly similar to 2109260A B cell 2 1
409168 N94037 Hs 312938 ESTs, Weakly similar to ALULHUMAN ALU S 21
410276 AI554545 Hs 68301 ESTs 21
443372 AI792557 Hs 133107 ESTs 2 1
422093 AF151852 Hs 111449 CGI-94 protein 21
402333 21
409374 R87083 Hs 19081 ESTs 21
412011 NM 000406 Hs 73064 gonadotropin releasing hormone receptor 21
412798 AW998657 Hs 119120 E3 ubiquitin ligase SMURF1 21
416085 H18072 Hs 92576 ESTs 21
418378 AW962081 gb EST374154 MAGE resequences, MAGG Homo 2 1
437846 AA773866 Hs 244569 esophagus cancer-related gene 2 21
452374 AL037405 Hs 339639 ESTs 2 1
450061 AI797034 Hs 201115 ESTs 21
450180 AW449644 Hs 257182 ESTs 2 1
405120 2 1
407378 AA299264 Hs 57776 ESTs, Moderately similar to I38022 hypot 21
458890 AW865523 gb PM4-SN0020-010400-009 b05 SN0020 Homo 21
435600 AL047034 Hs 119747 ESTs 21
440964 AI733106 Hs 130218 ESTs 21
417455 AW007066 Hs 18949 ESTε, Weakly similar to CA2B.HUMAN COLLA 21
436461 AW511956 Hs 293261 ESTs 21
436777 AA731199 Hs 293130 ESTs 21
427521 AW973352 Hs 290585 ESTs 21
413646 BE155042 gb PM0 HT0349 101299 002-E04 HT0349 Homo 21
413231 D87461 Hs 75244 BCL2-lιke2 21
423969 AI830571 Hs 331633 hypothetical protein DKFZp566N034 21
411518 AW850246 gb IL3-CT0219-291099 021-E07 CT0219 Homo 21
443777 AV646510 Hs 41185 Homo sapienε mRNA cDNA DKFZp56401262 (f 21
416148 H22453 Hs 169187 ESTs 21
402528 21
431215 AA496078 Hs 121554 Human DNA sequence from clone RP11-218C1 21
436820 AI684535 Hs 200811 ESTs 21
446209 AI375025 Hs 153368 ESTs 21
453362 H14988 Hs 107375 ESTs 2 1
417430 AA984546 gb am88e08 s1 Stratagene schizo brain S1 21
401069 21
454078 AA601518 Hs 22209 sxreted modular calcium binding protein 21
410966 AW812088 gb RC4-ST0173-191099 032-a07 ST0173 Homo 21
447124 AW976438 Hs 17428 RBP1-lιke protein 21
449939 T86420 Hs 272139 ESTs 21
411693 AW857271 gb C O-CT0307-210100-158-g09 CT0307 Homo 21
438005 BE151746 gb PM1-HT0305-061299 003-a06 HT0305 Homo 21
443486 NM_003428 Hs 9450 zinc finger protein 84 (HPF2) 21
407884 BE075316 Hs 95011 syntrapfiin, beta 1 (dystrophin-assxiate 21
404694 21
406668 T62745 Hs 184411 albumin 21
441092 T99289 Hs 126556 EST 21
454643 BE006345 gb RC2-BN0127-240300-011-d05 BN0127 Homo 21
426646 AA382787 Hs 122713 ESTε 21
431605 AW972407 gb EST384498 MAGE resequences, MAGL Homo 21
414452 AA454038 Hs 29032 ESTs 21
401991 21
457176 AA436837 gb zv57g07 s1 Soareε testis NHT Homo sap 21
436464 AI016176 Hs 269783 ESTs, Weakly similar to ALU1 HUMAN ALU S 21
428208 AA442327 Hs 104854 ESTs 21
445049 AV652718 gb AV652718 GLC Homo sapiens cDNA clone 21
419116 AF292402 Hs 283093 neuromedm U receptor 2 21
427894 AL135709 Hε 28921 zinc finger protein 21
424296 AI631874 Hε 155140 casein kinase 2, alpha 1 polypeptide 21
424323 AA338791 Hε 177788 ESTs 21
404582 21
418631 AA225921 Hs 115105 ESTs 21
424872 AA347923 gb EST54302 Fetal heart II Homo sapiens 21
452539 AW105321 Hs 49367 ESTs 21
454658 AW812330 Hs 11123 DKFZP564G092 protein 21
440310 AA878939 Hs 125406 ESTε 21
433297 AV658581 Hs 282633 ESTs 2 1
410900 AW810169 gb MR4-ST0124-040500 007-h07 ST0124 Homo 21
419386 AA236867 Hs 143868 ESTs, Weakly similar to I38022 hypotheti 21
402451 21
447842 AW160804 Hs 247302 twisted gastrulation 2 1
453880 AI803166 Hs 28462 ESTs, Weakly similar to I38022 hypotheti 21
425189 H16622 gb ym26c07 r1 Soares infant brain 1NIB H 21 457225 AW820035 Hs 278679 a disintegnn and metalloprotemase doma 21
400612 2 1
402318 21
410534 AW905138 gb QVO NN1071-280400-207-g07 NN1071 Homo 2 1
410878 AW809201 Hs 314248 ESTs, Weakly similar to ALU4.HUMAN ALU S 21
412029 AW886238 gb RC5-OT0078-280300-022-F01 OT0078 Homo 21
414494 AA768491 Hs 6783 hypothetical protein FLJ22724 21
427027 AI924294 Hs 173259 uncharactenzed bone marrow protein BM03 21
444498 AI151413 Hs 26330 ESTs 21
435191 R15912 Hs 4817 Homo sapiens clone 24461 mRNA sequence 21
425324 M89470 Hs 155644 paired box gene 2 21
430719 AA488988 Hs 293796 ESTs 21
432577 BE208545 Hs 317590 hypothetical protein FLJ 14640 21
407593 AW044083 Hs 237008 ESTs 21
401098 21
440299 AI871778 Hs 250112 ESTs 21
414146 BE549372 Hs 317596 Homo sapiens cDNA FLJ12927 fis, clone NT 21
428627 BE002993 Hs 187660 putative Rab5 GDP/GTP exchange factor ho 2 1
451806 NM 003729 Hs 27076 RNA 3'-termιnal phoεphate cyclase 21
431912 AI660552 Hs 154903 ESTs Weakly similar to A56154 Abl subst 21
439831 AW136488 Hs 25545 ESTs 21
451829 AW964081 Hs 247377 ESTs 21
404595 2 1
421498 AA292084 Hs 191575 ESTs, Moderately similar to ALU2_HUMAN A 21
456083 U46922 Hs 77252 fragile histidine triad gene 21
440527 AV657117 Hs 184164 ESTs, Moderately similar to S65657 alpha 21
406413 21
439483 T69980 Hs 58323 Homo sapiens cDNA FLJ11613 fis, clone HE 21
446242 N66336 Hs 7360 ESTs 2 1
449625 NM 014253 Hs 23796 odz (odd Oz/ten-m, Drosophila) homolog 1 21
457938 AI373638 Hs 133900 ESTs 2 1
413101 BE065215 gb RC1-BT0314-310300-015-f01 BT0314 Homo 21
408350 AW183350 Hs 250127 ESTs 2 1
419812 NM 000562 Hs 93210 complement component 8, alpha polypeptid 21
430881 NM 000809 Hs 248112 gamma-aminobutyπc xid (GABA) A recepto 2 1
429682 NM 006306 Hs 211602 SMC1 (structural maintenance of chromoso 21
409955 U60665 Hs 57692 chromosome 6 open reading frame 10 21
435579 AI332373 Hs 156924 ESTs 21
436088 AA704687 Hs 191294 ESTs 21
430223 NM 002514 Hs 235935 nephroblastoma overexpressed gene 21
416100 H18700 Hs 268799 ESTs 21
403218 AL134878 Hs 119500 πbosomal protein, large P2 21
409747 H60964 Hs 331250 ESTs 2 1
428764 W21550 gb zb52f12 r1 Soares_fetal_luπg_NbHL19W 21
425075 AA506324 Hs 1852 xid phosphatase, prostate 21
409432 D49372 Hs 54460 εmall inducible cytokine subfamily A (Cy 21
428299 AL038004 Hs 29419 ESTs 2 1
406817 AI936028 gb wo47a09 x1 NCI CGAP Gas4 Homo sapienε 21
411940 AW876686 gb CM4-PT0031-180200-507-e05 PT0031 Homo 21
412446 AI768015 Hs 92127 ESTε 21
414012 AW452334 Hs 128148 ESTε 21
421966 AA904519 Hs 130710 ESTs 2 1
430566 AA481282 Hs 190149 ESTs 21
456606 AA292862 Hs 275369 ESTs 21
451604 T65365 Hs 172851 arginase, type II 20
440926 AW196772 Hs 131323 ESTs 20
420687 AA279392 Hs 88605 Homo sapiens cDNA FLJ 13427 fis, clone PL 20
459082 BE551721 Hs 282149 ESTs 20
413241 BE073771 Hs 302414 Homo sapiens clone FLB8945 PR02411 mRNA, 20
426917 AA913814 Hs 172854 DKFZP586B0923 protein 20
447552 AI394125 Hs 160413 ESTs 20
420905 AA521307 Hs 186651 ESTε 20
428052 AA420477 Hs 26993 ESTs 20
424308 AW975531 Hs 154443 minichromosome maintenance deficient (S 20
432527 AW975028 Hs 102754 ESTs 20
430202 T85775 gb yd60g02 r1 Soares fetal liver spleen 20
446610 AV659433 Hs 282984 ESTs, Weakly similar to I38022 hypotheti 20
427961 AW293165 Hs 143134 ESTs 20
455290 U75810 gb HSU75810 Human Homo sapiens cDNA don 20
445564 AB028957 Hs 12896 KIAA1034 protein 20
412811 H06382 Hs 21400 ESTs 20
413783 AA314337 Hs 301547 πbosomal protein S7 20
423867 AA331886 gb EST35757 Embryo, 8 week I Homo sapieπ 20
429418 AI381028 Hs 118769 ESTε 20
431511 NM 012386 Hs 258581 Homo εapiens p95 paxillm-kinase linker 20
445829 AI452457 Hs 145526 ESTs 20
452366 AK000464 Hs 29276 hypothetical protein FLJ20457 20
453123 AI953718 Hs 221849 ESTs 20
455401 AW936369 gb QV4-DT0021-301299 071-d07 DT0021 Homo 20
406666 V00495 Hs 184411 albumin 20
445688 AI248205 Hs 153244 ESTs 20
446131 NM 000929 Hs 290 phospholipase A2, group V 20
440388 AI693520 Hs 223000 ESTs 20 457128 AI932995 Hs 183475 Homo εapiens clone 25061 mRNA sequence 20
404416 20
444187 AW138466 Hs 151274 ESTs 20
431552 AI815863 Hs 259873 axonal transport of synaptic vesicles 20
455814 BE141689 gb CM1-HT0092-220999 016 b09 HT0092 Homo 20
454759 AW819455 gb RC5 ST0293 021299 031-A04 ST0293 Homo 20
426497 AA379913 gb EST92807 Skin tumor 1 Homo sapienε cD 20
404420 20
408112 AW451982 Hs 248613 ESTε 20
432702 AW973953 Hs 293744 ESTε 20
448587 AI539652 Hs 28338 KIAA1546 protein 20
446854 BE268103 Hs 208914 hypothetical protein MGC10999 20
410569 AA766825 Hs 205675 ESTs 20
432596 AJ224741 Hs 278461 matnlin 3 20
402341 20
452919 AW962167 gb EST374240 MAGE reεequeπceε, MAGG Homo 20
433632 AA649921 Hs 112553 ESTε 20
435079 AA664192 gb ac05b03 s1 Stratagene lung (937210) H 20
451927 AL355687 Hs 27261 Homo sapiens mRNA full length insert cDN 20
432839 AA579465 Hs 45207 hypothetical protein KIAA1335 20
450895 N66727 Hs 10957 ESTs 20
408459 H09701 Hs 278366 ESTs, Weakly similar to I38022 hypotheti 20
400842 20
455797 BE091833 gb IL2-BT0731-260400-076-F04 BT0731 Homo 20
400859 20
405829 20
411863 BE075244 Hs 12420 ESTs 20
415258 AW752247 Hs 293853 ESTs 20
416093 R60685 Hs 268698 ESTs, Moderately similar to ALUC.HUMAN ι 20
420314 H81671 Hs 320921 ESTs, Weakly similar to T22688 hypotheti 20
428002 AA418703 gb zv98c03s1 Soares NhHMPu.SI Homo sapi 20
437733 AI792574 Hs 122876 ESTs 20
453118 AW195849 Hs 252757 ESTs 20
457039 H29990 Hs 101937 sine xulis homeobox (Drosophila) homolo 20
454578 AW809178 gb MR4-ST0118-261099 012-c07 ST0118 Homo 20
411565 AW851728 gb MR2-CT0222-011199-007-d06 CT0222 Homo 20
419986 AI345455 Hs 78915 GA-bmding protein transcription factor, 20
415173 AW501735 Hs 253015 ESTs 20
449011 AI655376 Hs 192693 ESTs 20
410365 AI287518 Hs 62669 Homo sapiens mRNA, cDNA DKFZp586D0923 (f 20
416057 AI927382 Hs 29857 ESTs 20
455688 BE067238 gb PM1 BT0348-151299-001-a12 BT0348 Homo 20
408531 AW207553 Hs 253639 ESTs 20
434663 AA641972 Hs 130058 ESTs 20
428085 AA421081 Hs 12388 ESTs 20
425006 R38685 Hs 332622 ESTs 20
446139 H77395 Hs 39749 ESTs 20
400049 20
428333 AW972668 Hs 293044 ESTs 20
429458 BE161832 Hs 292689 ESTs 20
425087 R62424 Hs 126059 ESTs 20
457122 AI026157 Hs 33728 ESTs, Weakly similar to ALU1.HUMAN ALU S 20
400310 X63966 Hs 135631 H sapiens synthetic gene for platelet de 20
451805 AI968300 Hs 208220 ESTs 20
401986 20
415318 T06544 gb EST04433 Fetal brain, Stratagene (cat 20
417756 Z43056 gb HSC12B021 normalized infant brain cDN 20
418301 AW976201 Hs 53913 hypothetical protein FLJ 10252 20
424698 AA164366 Hs 151973 hypothetical protein FLJ 23511 20
429110 L29301 Hs 2353 opioid rxeptor, mu 1 20
433755 AW085934 Hs 120868 ESTε 20
434118 AF116715 Hs 256256 Homo εapienε PR02829 mRNA, complete eds 20
435413 AI267476 Hs 46669 ESTs 20
443748 AW206447 gb Ul-H BH-afg-g 02-0-UI s1 NCI CGAP.Su 20
445205 D83776 Hs 12413 KIAA0191 protein 20
458175 AW296024 Hs 150434 ESTs 20
446419 AW576760 Hs 160726 Homo sapiens cDNA FLJ11680 fis, clone HE 20
441627 AA947552 Hs 58086 ESTs 20
457653 AI820719 Hs 154662 DnaJ (Hsp40) homolog, subfamily A, membe 20
455614 AI693369 Hs 202274 ESTs 20
449899 AI610700 Hs 103280 ESTs 20
420111 AA255652 gb zs21h11 r1 NCI CGAP GCB1 Homo sapiens 20
437354 AA749215 Hε 291886 ESTs 20
412228 AW503785 Hs 73792 complement component (3d/Epsteιn Ban vi 20
419691 W03298 Hs 193521 ESTε 20
439724 AF086565 Hs 60351 EST 20
413362 BE088812 gb CM2-BT0693-230300-129 d08 BT0693 Homo 20
453652 AW009640 Hs 28368 ESTε, Moderately similar to S65657 alpha 20
434361 AF129755 Hs 117772 ESTs 20
442479 AF069484 gb AF069484 Homo sapiens astrocytoma lib 20
413554 AA319146 Hs 75426 sxretogranm II (chromogranin C) 20
459323 AW062490 gb MR0-CT0065-100899 001-d01 CT0065 Homo 20
449438 AA927317 Hs 554 Sjogren εyndrome antigen A2 (60kD, πbon 20 400285 20
407407 AF050198 gb Homo sapienε putative mitochondnal ε 20
411459 BE142707 gb R0-HT0157-191199-002-g 12 HT0157 Homo 20
417383 W02642 Hs 136102 KIAA0853 protein 20
447153 AA805202 Hs 315562 ESTε 20
447313 U92981 Hs 18081 Homo εapieπs clone DT1P1B6 mRNA, CAG rep 20
455696 BE067870 gb RCO-BT0362-021299-031-b06 BT0362 Homo 20
456510 AK001652 Hs 99423 ATP-dependent RNA helicase 20
449815 AI671000 Hs 199739 ESTs 20
425398 AL049689 Hs 156369 hypothetical protein similar to tenascm 20
400238 20
451678 AA374181 Hε 26799 DKFZP564D0764 protein 20
445073 AW291389 Hs 13056 hypothetical protein FLJ 13920 20
455221 AW867751 gb MRO-SN0038-290300-001-a03 SN0038 Homo 20
413174 AA723564 Hs 191343 ESTs 20
435810 BE349853 Hs 2785 keratin 17 20
418687 R61650 Hs 22581 ESTs 20
438563 AA810665 Hs 134746 ESTs, Weakly similar to A46010 X-linked 20
431750 AA514986 Hs 283705 ESTs 20
453242 T98327 Hs 18343 ESTs 20
437074 AI286235 Hs 128905 hypothetical protein FLJ13204 20
459411 N52920 gb yv34h09 s1 Soares fetal liver spleen 20
424834 AK001432 Hs 153408 Homo sapiens cDNA FLJ10570 fis, clone NT 20
409929 R38772 Hs 172619 myelm transcnption factor 1-lιke 20
406378 20
459208 BE261314 Hs 149039 ESTs, Weakly similar to I38022 hypotheti 20
445260 AI218133 Hs 147617 ESTε 20
416248 H99169 Hs 23450 mitochondnal nbosomal protein S25 20
445020 AI205655 Hs 147221 ESTs 20
402048 20
412695 AW984439 gb PM3-HN0011-220300-002 c05 HN0011 Homo 20
416408 R94725 Hs 35354 ESTs 20
423347 AI660412 Hs 234557 ESTs 20
427836 AA416642 Hs 116176 ESTs 20
433347 AF023130 gb Homo sapiens Ras-GRF2 mRNA, partial c 20
436902 AW247145 Hs 192729 ESTs 20
440122 AI733011 Hs 127678 ESTs 20
442901 AI023654 Hs 114191 ESTs 20
444097 AW517412 Hs 150757 ESTε 20
447278 AI934935 Hs 158669 ESTs 20
451361 AA053854 gb zf52f02 r1 Soares retina N2b4HR Homo 20
451813 NM 016117 Hs 27182 phospholipase A2 xtivatiπg protem 20
454423 AW603985 gb RC4-CN0048-140100-011-a04 CN0048 Homo 20
458801 N98648 Hs 276860 ESTs, Weakly similar to C Cham C, Human 20
TABLE 30B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT number Accession
407593 1003161 1 AW044083 AW044094 AW370634 407594 1003220 1 AW057584 AW057585 AW044153 R34370 407639 1006924 1 AW205369 AW058599 AW207608 407676 1008294 1 AW064111 AW064450 AW064429 407721 10108.1 Y12735 NM.003582 AW238970 R38268 R41411 R41419 T16717 AA002193 H62028 AI359545 AW105201 AW087158 AA699728 AI095264
AA002065 H62029 AI289101 AA884804 AA904950 AA609672 AI139874 H77896
407726 101126.1 AA435679 AA470655 H22526 AA044031 AA876426 W63767 AI421140 A1418990 H42329 H88910 AL041066 H88909 W94610 AW352277 W94648
W94167 AW952568 AI419653 AA335501 AA393641 AA044353 H41626 H22525 R58582 AW297645 C75230 AW368034 AW468904 AI272755
407762 101439 1 AW235638 AA346882 AW866803 AA361281 AW963163 AA044373 AA136755 407764 1014849 1 BE008347 BE008320 BE083307 BE083311 AW075968 407788 10163.1 BE514982 BE614814 AW393078 AW238480 AA055637 N27644 AA641158 M87068 AA161019 AA161003 AA587315 AA716746 AA593632
AI354870 AW183492 Y07755 NMJ05978 AW872948 AI608987 H64656 AF086003 AA643149 AI819402 H64555 AA858398 AA594885 AI436747
BE122811 AA587026 AW857106 AI950679 AA596012 AA654004 AW238238 AI971395 AA459074 AA458884 AI608591 BE181995 BE181970
AW195797 C00271 BE182043
407803 1017498 1 AW081681 N36967 N36959 407809 1017982 1 AW082279 AW082688 407811 10180 1 AW190902 AI802788 AI041650 AI037867 AF110137 NM.013372 H99469 N35377 AW151676 AI678451 AW078795 AW087935 AI884505
AW044602 AB032372 AF045800 AI621183 AI750578 AA376403 AI910477 AA373348 AA373673 AI752124 AL359060 W48619 AA373298 AA373975
AW604409 AW604404 AW368603 AA545734 AW361415 AA373557 AW956164 AW853798 AI750595 AL359059 AA344024 N31127 AW580737
N27040 AA071138 AI753050 AA599801 W48852 AA669811 AA112124 A1940705 W52686 AA084001 C01826 AI940729 AA373544 AW957491
AW383224 AW383164 AW383192 AW383125 AW383194 AW842507 AI940795 H80042 AW631119 W47324 W42884 AI750594 AI754387 AI753734
AA372833 AW069006 AI750577 AW473621 AI888605 AA600082 AI041803 W51909 W25447 AI521673 AI087351 AA670070 W47325 AA071381
W42791 AI090390 AI085102 AI302125 AA788723 AW069430 AW069485 AI754608 AA373014 BE140150 BE140166 BE140102 BE140143
BE140157 BE140117 BE140098 AW005943 BE140108 BE140176 BE140171 BE140144 BE140175 BE140160 BE140152 BE140099 BE140177
BE140167 BE140145 BE140109 BE140163 BE140172 BE140161 BE140179 BE140147 BE140107 BE140146 BE140155 BE140173 BE140148
BE140174 BE140158 BE140149 BE140116 BE140156 BE140105 BE140103 BE140164 AW138508 BE140153 AW806557 BE140121 BE140162
C01953 AW806500 BE140124 AA329219 AW955642 AW069165 AI968107 N21113 AI754594 AW069264 AI754660 BE551937 AA543066 AA703927
AW130486 AI814434 AI924946 AA789056 AW173667 AW069841 AI022286 AI753523 AI753558 A1753482 AW068940 AI753002 AA669866 AI753593 AI753469 AI753506 AW008360 AI753255 AI949111 AI752123 W19275 AI679005 AI888455 AI677772 AI589279 AI968546 AW069588
AI754028 N20040 AI754354 AI752878 AA836970 AW631283 A1440410 AW016646 AI801326 AI610424 AI521669 AI446171 AI453455 AI753087
AA670062 AA599863 AI753621 AI802571 AI537325 AA669978 AI921732 AI811571 AI309543 H80043 AI623845 AI623852 AI075634 AI919521
AA729459 C01795 AA577421 AA668620 AA600003 AA653400 AI445339 AW468974 AW130343 AA600104 AW970482 AW806615 BE140122
407834 1020170.1 AW084991 R54179 64486 407851 10212.1 NM.014496 AF184965 H82896 H82897 407884 1023626.1 BE075316 AW090150 AW589417 H47391 D61911 BE173252 407938 102759.1 AA905097 A1734242 BE044545 N86431 AA344041 C03245 AW963097 AI567324 AA045934 AW079233 R58274 AI744425 AI167427 R58176
R58598 AI969945 AI921684 AW013864 AI204559 AA909648 N84115 AA897468 AI668637 BE221753 AI355307 AI139542 N80934
407965 10298.1 W21483 U15590 NM 006308 N56314 AA126678 AA426507 Y17782 W24740 W05062 W21042 AA649552 AA093507 AA092088 AA476830 N88299
AA429090 AA095643 AI224915 AA443775 AI204315 AI333690 AA586584 AI275037 AI193915 AA659647 T82641 AA136048 T82643 T82647
F36041 N74099 AI572217 T82650 T82642 T82640 R47360 R47361 R47357 N74672 R47356 R47355 N93086 R47354 R47353 R47342 R47362
R47358 N93441 N56384 N93566 T82622 T82618
407995 1031771 AI094748 AW241797 AI759976 T10509 AI814441 AI421977 AI423762 N73686 T11392 AA046406 408000 1031.1 L11690 NM 001723 M69225 H99965 A1750335 BE000199 M63618 N31521 AA112876 AW265395 AA088909 N21507 X58677 U04850 AW864903
AI830854 AW361101 AW379356 AA301170 T29232 AW965998 H26216 H44230 H44784 AA808916 AA514765 H44575 AA705179 AA586735
AW589403 H25843 AA654993 AI783826 BE087370
408112 1039850.1 AW451982 AW157117 AW161544 408172 10441051 W02488 AW167479 AW361027 AW833243 408221 104826.T AA912183 AA541622 AI673341 AI266109 AI335896 AI421010 AA053327 AI982962 AI372854 AI674348 AA531087 AI801016 AI372855 AI817816
N52151 D62928 AI401633 AI378549 AI378800 AI337972 D62536 AW972977 AA135826 BE222491 D62195 BE326453 AA225293 AA236461
R85586 AA625141 AA058641 AA135825 AA234644 H50784 R71863
408235 104868 -1 AA053381 408238 104872.1 W95901 AA053387AA121501 408243 10481 Y00787 M28130 D14283 BE439795 BE439924 AA362187 BE439515 M17017 C05929 AA381897 AA346136 AA381472 C06304 AA381670
AA381679 AA381965 T11274 AA381318 AA381601 AA381700 AA381952 AW950718 AA381992 D82198 AA381914 AV653399 AA362140
AA381592 AA381967 AA381 54 M26383 AA362188 AA382057 AA381781 AA362246 AA381669 AA381395 AA381845 AA381848 AA381603
W40425 AW663238 AA381702M381355 AA381356 AA381653 AA362127 AA374516 AA381426AA381767AA362270 AA381459AA362358
AA362160 AA304441 T27482 D83848 AA381877 AA381623 D83851 AA362133 AA381999 AA372837 AA362192 AA362196 AA381806 D82132
AA362107 AA363589 AA296403 T11316 D82218 AA381456 W56111 AA381435 W40163 T11379W40283 D82615AA382121 W40401 AA381699
T68485 D82618 W52968 W39356 T27467 D83813 Z11686 T10915 AW367405 AW604306 AA363550 AA363514 BE004230 AA381218 W40279
AA363545 AW377023 AA363453 AA363559 AA381833 AW850620 AA381813 AA381710 AA381584 AA381577 AA381715 AW376990 T11334
AA305271 AA363554 W52491 AW631242 AA363599 D82254 AA363540 AA363596 AW951160 BE122704 AA380965 AW850702 AW630501
AA381229 AA381228AA381576AA381795AA381816AI274317AA360958AA381517AA381618AA381891 AI310352T11037 BE122702
AA834388 W38334 C01358 AW059870 AA371394 AW075978 AI922031 AA381189 AW468452 AI375262 AI870149 C06055 AA381309 AA381625
AA381252 AI620395 AW467642 AJ227913 AW780131 AI742278 AI564251 C75559 AW272612 AI634748 AW339521 AI079248 C75557 AI569162
C75493 AW591509 AW769268 C75524 AI469809 AI579895 C75486 AI697109 AI475413 AI355474 AI282685 AI087873 AI469815 C06100
AA568576 AW014817 C05914AW272671 C75615 AW337841 AI380580 AW467270 AA847352 W46290 AW780211 AW440851 W45324 C06017
C75643 AI346866 W45040 C05698 C05704 AA381931 AA381177 AA382015 AI476632 AA381274 C05758 C75413 W45362 AW951601 C05910
C75382 W60423 AA095727 C75410 AW188453 AW341742 W60450 AW613454 AI469266 AI473944 BE042737 AW273112 AW467973 C05693
AW272835 W45409 C05668 AI431254 T29157 A1953422 AW510601 W45271 C75538 BE138893 AW662358 AA102526 AI457250 AW615017
AW662707 AW051250 AW470168 AI952442 AA362337 AW015490 AA362269 BE122713 C06363 C06353 AW779405 T68419 AA381217 AA362139
T11140 T11198 AA363591 AA362138 AA362357 AA362344 D56519 AA362132 AA361981 AA362159 AA362110 D83856 D82102 D83842
AW959358 AI373550 AA362225
408281 1050256.1 BE141183 AW178167 AW178162 AW178166AW178172AW845893AW178159AW178222AW178213 AW178215 AW178090 AW178091 AW178161 AW178207 AW178210 AW178214 AW178212 BE140918 BE140917 AW178135 AW178205 AW178209 AW178223 AW178220 AW178206 AW178203 AW178165 AW178168 AW178160 AW178136 AW845878 AW178131 AW178138 AW178105 AW845894 AW178129 AW845810 AW845828AW178216AW178112 AW178211 AW178224 BE140915 AW178221 AW178130 AW178134 AW178096 AW178108
AW178133AW178164AW178218 AW178171 AW178157 AW178158AW178103 BE141189 AW178170 AW845816 BE141586 AW178156
AW178104AW178163AW178093 AW178208 AW178137 AW178140 AW178219 BE141592 AW845901 BE141580AW178155 BE141598 BE140957
408332 10520561 H91230 AW182672
408334 10520791 AW514652 AW612492 AW182695
408350 10526761 AW183350 C03487 C05115
408408 105661 AF070571 H70949 AW149569 AI804276 AA936447 AA987912 N35082 N35065 N43822 N43804 H69776 T80170
408459 10598301 H09701 R35799 R19028 AW196589
408531 10645781 AW207553 BE221925 BE551043
408617 10700701 R61736 AW242757 R53961 T33418 Z45363
408691 10749331 AW250525 BE265117
408729 1077221 AA195764 AA167076 AW937980 AA166917 AA056984 AI206035 AW023639 AA195520 AA329676 AA678589 AI784331
408749 1078708.1 H65489 AW876581 AW876552 AW268587
408751 1078907.1 N91553 AW268820 AW566003 W19061
408812 1083877.1 BE397160 AW274839
408908 108932 BE296227 AF008551 Z43879 AA313688 AW409753 AA298501 AW957623 BE299015 BE093498 AA431134 N64029 AI038260 AW732512 AI917458
AA628301 AA291514 BE092461 H63889 AI126792 BE092286 H72166 H57643 AI884785 R96793 AW516673 W78726 H78488 BE011847 AI638439
AA834453 AW014897 AI004050 AA804577 AI207188 AW365050 AI689761 AA432153 AA767736 AI738674 R19158 BE503915 AA629662
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AA633879 AA706479 AA706213 AA706197 AA679805 AA683208 AA679343 AA613172 AA679833 AA085131 AA679793 AA601666 AA210946
AA583228 AA601229 AA084718 AA584501 AA224217 AA706452 AA489324 AA587310 AA082786 AA586892 N23070 AA211405 AA082906
AA489789 AA209324 AA206631 AA167636 AA188956 AA666070 AA19S718 AA214195 AA113862 AA206791 AA633796 AA223986 AA083048
AA085009 AA085307 AA207042AA214235 AA166892 AA188689 AA211101 AA706139AA773961 AA773972AA189090 AA668591 AA213387
AA206041 AA199719 AA223995 AA085386 AA199670 AA199904 AA199651 AA084336 AA167637 AA666175 AA223978 AA707341 AA214110
AA633741 AA205951 AA214421 AA666402AA188669 AA161379 AA084747 AA211176 AA664225 AA169244AA714142 AA679457 AA668573
AA206000 AA780452 AA454542 AA706364 AA706507 AA706570 AA722308 AA707242 AA704053 AA707423 AA722261 AA703686 AA703777
AA707238 AA706366 AA707433 AA706380 AA703761 AA706572 AA704109 AA706275 AA704117 AA707250 AA774043 AA707349 AA679485
AA214199 AA666241 AA779045 AA668507 AA668597 T03211 AA664313 AA214112 AA668518 AA214159 AA214297 AA085030 AA211088
AA209254 AA214326 AA213476 AA205166 AA223713 AA223626 AA213473 AA199706 AA224108 AA223973 AA167729 AA213641 AA211125
AA199730 AA223972 AA161387 AA668335 AA434073 AA679481 T82447 AA085177 AA633886 T49882 AA214251 AA085153 AA214425 AA223838
AA160951 AA224107 AA214341 AA372581 AA309169AA199705AA346242AA211015 AA224156 AA083161 AA176787 AA224038 AW374738
AA224043 AA209284 AA224039 AA213681 H55496 AA213640 AI267801 AA206853 T82077 BE150566 AA811950
457024 274501 1 AA397546 AA699372 AA699363 AA399064 457030 27473.1 AI301740 AL119574 AW504484 BE560671 BE269112AW897591 T31233 U17279AW504792T32181 Z47338 T05711 AL121247 AW504876
AW161725 AI204992 D38743 D38661 AW895130 AA985067 AL120318 AA326654 AW955387 AA776607 D38742 AI267812 AL035910 BE008426
BE008367 AA423862 BE348785 AA249436 AA326809 AA325529 AW361428 N24212 AW302831 AI583363 AW470460 AL038861 AA234531
AI376141 AA194854 W35263 N39248 D52746 D55494AA083749 D52828T30063 T31624 D54617 AA112066 BE018814 AW882900 M78702
T31558 T31691 AW859799 AA310616 AW389747 AA317897 T31158 AI077640 AA386250 T10323 D53660 F05613 AL120458 H15866 AW895727
AW895802AW899191 AA128798 N31267 H14732 BE208125 N64235 H97218 AA236449 BE087062 F11649 F11648 Z42310T32845 U47717
H43263 Z44143 T05325 T16885 AL138108 H84437 AA197265 N46693 AW020269 AA070847 AW022743 AW885792 M78703 AA486340 T07147
N36340 T35393 AW841129 AI288455 BE005370 AI497892 C14978 AA487674 T30747 AW022976 AA860826 AA730653 AA857741 T08861 N67128
AI127818 AA886918 AI424496 AI004685 D55084 AA747954 AI128832 W23585 Z41668 H84438 AI611575 AI350797 AA502260 AI364537
AA638970 U97105 NM 001386 BE009933 BE546254 BE396357 BE513831 W26313 H10568T97273 T33131 T07524 AW276666 R15142T30810
F07479 T33812 H24219 AV647683 AV646892
457039 275248.1 H29990 N44636 N44265 AW292774 AA398365 R92869 AA403200 457040 27530.2 N77624 AW607635 H03232 N46965 H94749 AW382351 R02203 BE169946 N56808 AA045401 AA046564 AA658111 N59303 H47303 R09001
AW023738 AW607549 H68307 R73086 W67321 AA126540 R27493 AA400212 AA044323 AA329416 AL037969 N54710 AA101647 D60371 N58245
D61743 H46463 AA126414 BE501495 AI765781 AW237498 BE219266 AA716110 AA031291 AA400123 C16598 AA045283 C16444 D62466
AW189929 AI143224 AA530868 AW194998 AW593426 AA813316 C16384 AI332909 AI335037 D57149 D45498 C16198 C16113 AA705203
AA777104 AI360091 C16168 N89583 W67248 AI469064 AI753912 N92420 AI862009 AI093246 AA101648 AI138331 AA296430 At302151 R25756
N34045 AW338083 AW139636 AI559099 AI184816 AI200476 AI127576 T82460 AI368362 AI435204 AI478453 AI093082 AI469352 AW338517
AI200250 AI031694 AI887286 AI033758 AW080370 AW029140 N32140 N52949 N50055 H47004 N76054 R51887 R73087 AI160363 H64018
W88748 AI081703 AA149098 R40542 N77209 H04380 AA234491 R08896 D57030 AI767209 AA600348 N70842 AA044242 AI888195 AA777676
AI538758 C16174 R38565 AI799219 H74312 F10055 W37697 F10343 AA610106 R52523 R22142 H88895 R77674 R44673 AA045199 R31568
AA505916 AI360773 F10337AA733180AI016479AW183400 AW779199 D58102 H64348 D57909 R26653AW051234 Z41044AA876777 F03579
AI680446 AA745688 T24075 T35116 T35115 R02091 Z30229 AI872774 AW772549 AI540411 AI784282 R25646 AA541817 T77442 R26596
BE166424 T77229 R23696
457041 275843.1 AA399018 AW242359 AI868208 AW020951 AA412180
457122 287827.1 AI026157 AA838752 AH46272 AA910825 AI266100 N24580 H97503 BE327388 AI697814 W56675 AA423842 AA423880 H40134 457128 28930.1 AI932995 BE064464 AW371902 AW371841 AI885885 BE064457 AA524113 AA721037 AA504343 AA778099 AI800598 AI693112 AI864633
AI690228 AI400990 AW969089 AW371927 AW371912AW383562 BE151089 AW383568 BE218503AW383570AW371899 BE151097AW371900
AW293095 AW292008 AA434179 AA714780 R45868 W01182 AW957767 AW119223 AI207864 W01578 AA354403 AA805177 AI613299 AW269636
AA481528 AW079101 AF131777 R60489 T81289 AA481594 BE181020 AA465433 AW808125 T84992 AA749191
457176 296527.1 AA436837 AA442594
457187 2989941 AA443927 AA444106
457225 30546.1 AW820035 T20260 T20259 AL049415 AA737756 W46965 W00799 AW340968 AW027417 AW263261 AI420674 AA814921 AA736509 N69991
AW368643 W47065 AI090172 AI924139 BE468071 AA375842 AA375767 AW628849 AI422731 AA494558 AA969233 AI142954 AI161089 AI167233
W94484 AI681576 AA249694 A1695943 AA832347 AA476621 AA937792 AI702870 AA455748 AW195100 AI638530 BE502479 AI383418 AA039630
C20777
457314 3186371 AA479597 Z45151 H28821
457460 3400381 AI143312 AI394343 AW205239 AA523980 AI831223 AI347180 BE263197 AA765781 AI654500
457506 346721 AF131757 T79901
457620 3715141 AA602711 BE078290
457630 3737841 AI680803 AI703329 AA609004 AI305245 AI457796 AW295787
457652 37972.1 AF116656 AH 14583 AW838134 AW838525 AW885447 H83251 AW838349 AW838378 AW838175 H83252
457653 379792 AI820719 AI273515 AW592687 AI263784 AI351926 R46866
457741 3957671 BE044740 AW827360 AW827623 BE161439 BE044718 BE046207 BE046551 AA653908 BE166581
457756 31 AA126136 H62964 BE245159 AF280094 AA431918 BE386201 AA707576 AI074267 AA969194 AA693596 H62844 AW134991 AA126014 AI077443
AA699881 AI037956 AA961277 AW204185 AI540791 AI273273 AW627S57 AA926890 AI014851 AW081056 AA443705 AW137571 BE139390
AI583851 AI583822 AI583814 AW268341 AI590502 AW302642 AI053871 AI254692 AI591255 A1590260 A1583359 A1583341 AI583752 AI224227
AW302089 AW466960 AA810124 AW302684 AI272921 AI141003 AW589738 AA074714 AA621482 AI796501 AW024557 AA621074 T62627
AA639206 AI913538 AA075135 R54613 AA352975 AW206892 AI868280 AW449243 AA907317 AW134573 AI590492 AI610050 AI834309 AI375556
AI284991 AW968038
457770 4025301 BE065030 AA670100 AA781546 AI022472 AA846803 AI497780 N68386 AI382890
457802 4100731 T78013 AA699327 W87785 W88613
457900 434061 1 AW976692 AA806542 AA745856
457938 4398371 AI373638 AI073389 AI087143 AA764776 AA913318
458023 4637171 AW978161 AW978165 AI016938 AI539270 AW294958 AW511089 AA814849
458037 466271 AF074982 R27906 R31333 R31591 R27812
458043 4669521 AW979009 AA828038 AA828148
458067 46875.2 AA393603 Z19481 AA252342 AI807614 AI913804 AA040176 AA971879 H53388 AF085972 AI291424 H53349 AW015078 AA768307 AA127921
AA723700 AA040841 AA993954 AA213655 AA127972 AA913063 BE327712 AI017585 AA988186 AA628183 AI205930 AA833558 AA974107
AI004390 H48931 AA724004
458175 4987441 AW296024 AA897109 AI015000
458227 5179131 Z40670 BE504110 BE219908 AW468668 AI002334
458257 5268541 U48351 AA969182 BE327312 AW138276 BE467567 AI680815 AI422668
458303 5431751 AI264628 AF017648 AS872732
458356 5552341 A1024855 AI024877
458426 5792691 AI084514 N46645 AW183984
458455 591001 AV648310 AV661871 AI928475 AV647819 T55845
458507 614471 1 AI185703 AI805813 AW292764
458552 6332591 AW136139 AI216724
458623 6622971 AI305223 A1458577 AI275569
458624 662652.1 AI362790 A1275996 N48887
458661 6770161 AI299789 BE551384
458684 685491 BE281115 T53860 AV659439 AV659421 BE539929
458734 7195151 AI554946 AW362008 AW362553 AI683342 AI376781
458762 730761 AW802754 BE619228
458763 731371 1 AI693417 AI418256 AW627792 F32979
458771 7373971 AW295151 AI425004 AW470228 AI693738 H50554 R99198 H50553 R98197
458797 75398.2 AW001835 AW612725 AW136670 AI798956 BE467368 AA280216 AI216754 BE622057 AL121193 AW853470 AW853450 AW369075 AW369108
AW578479AW369106 AW361242AW361190 N79183
458801 756691 N98648 AI458157 BE041652 BE218014 BE622355 AA369340 AA369515 AW962780 AW962704
458817 7644591 AI522129T56009 R53849
458833 7775051 AW236702AI566105 Z40396
458861 7980851 A1630223 AI630470
458890 8127332 AW865523 AW865128 AW865467 AW865127 AW865466
458925 82655.? R15891 R61471 R61469 N69765 AI014624 AA007214 AW592075 H09780 AA709038 AI335898 H11055 AI559229 F09750 T72573 AA935558
AA988654 AA826438 AI002431 AI299721
459023 86727.1 AW968226 AI139249 AI701692 AA017303 AW469622 AA258148 AA811690 AA807996 AA744260 AA824494 AA731710 T25332 AA258101
AA970687
459037 874171 AW439497 AI826059 AA018402 AA837392
459082 8895331 BE551721 H51878 AI823338 C01488 AW813562
459124 9165751 AW301478 AW301560 AI889207
459207 9267041 AW138410 AI912712 N40186
459208 927171 BE261314 AI243406 AA027322
459275 973181 AI808913 AW028342 W81290 AI571379 AI382808 AA037071 W79688 R48751 N31808 AI870233 R48752 AW024895 AI333754
459278 9751 1 AW294659 AI204928 AA351653 H51220 R86843 AA993182 U79298 R15294 F05089 Z42963 R17818 T77498 AA332319 W56049 AA331586
AW881873 AW881865 AW881876 R52345 AI652070 AA400044 AA401512 T08151 W05486 N68378 T33846 AI190920 R43021 AIS49980 Z39084
T63413 W37269 F01343 R86669 AI621055 AW117593 AI193211 AW297932 AI500709 AA400056
Table 30C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 400462 9929659 Minus 197610-197785
400608 9887666 Minus 96756-97558
400612 9929646 Minus 151513-151662
400631 8247025 Minus 56203-56313,56424-56482,5707357185,57513-57593,57747-57941
400641 8117693 Plus 4786-4992
400664 8118496 Plus 13558-13721,13942-14090,14554-14679
400696 8118812 Minus 77737-77899
400697 8118812 Minus 79073-79198
400706 7249204 Minus 78299-78686
400816 8569993 Plus 161221-162078
400842 1927148 Plus 90462-90673
400859 9757499 Minus 91888-92018,98131-98294,99474-99570
400861 9757506 Plus 163855-164016
400889 9958234 Minus 169782-170036
401069 3927852 Minus 45682-45831
401098 9965518 Minus 85632-86174
401132 8705350 Minus 85679-85795
401189 9690246 Minus 90815-90929
401200 9743387 Minus 111586-111806,114791-114916,115419-115583,116351-116446,116847-116907,122853-123067,124982-125407
401240 3355450 Plus 77433-77636
401324 9863791 Plus 234057-234174
401365 9796180 Minus 119572-119672
401368 8670914 Minuε 65508-65662
401459 9212270 Minuε 182001-183323
401462 6682291 Pluε 112763-112909
401497 7381770 Plus 92607-92813
401526 7770561 Plus 91570-93177
401596 3293210 Plus 63639-63890
401614 7839924 Plus 17350-17735
401626 8575943 Minus 238100-238432
401645 7657839 Minus 34986-35133
401673 7689903 Minus 122587-122705,122765-123047
401694 3540172 Minus 6405664168
401785 7249190 Minus 165776-165996,166189-166314,166408-166569,167112-167268,167387-167469,168634-168942
401878 8099802 Minus 162268-162474,163089-163195
401887 7229981 Plus 93973-94120
401899 7230209 Minus 155620-155815
401986 4406829 Minus 31137-31293
401989 4309964 Minus 118611-118821
401991 4156128 Plus 2398-2513
402048 8072512 Plus 4393644078
402076 8117410 Plus 128316-128627
402090 7249154 Minus 104806-104939,106898-107052
402112 8139750 Plus 10507-10713
402131 7704961 Minus 33114-33209,33496-33678
402145 8018280 Plus 113086-114800
402318 7582559 Minus 12843-13403
402333 8844110 Minus 165693-165856
402341 7656696 Plus 22583-23699
402369 9558577 Minus 50417-50522
402451 9796677 Minus 48137-48343
402528 7630857 Minus 169609-169742
402603 9909396 Minus 141663-141852
402615 9926801 Plus 131390-132157
402689 8348025 Minuε 5885-6209
402942 9368398 Pluε 102152-102386
403011 6693587 Minuε 3468-3623
403053 8748888 Plus 146568-146659,147539-147811
403089 8954241 Plus 171964-172239
403188 9838289 Minus 157618-157755
403218 7630969 Plus 58039-58149
403271 7230852 Plus 134283-134485
403281 8072630 Minus 7521-7728
403306 8099945 Plus 127100-127251
403310 8139936 Minus 183883-184026
403317 8318526 Minus 50623-50834
403329 8516120 Plus 96450-96598
403341 8569175 Plus 30699-30910
403344 8569726 Plus 70823-70990
403356 8569930 Plus 92839-93036
403513 7656757 Minus 155310-155436,158402-158535
403515 7656757 Minus 173358-179553
403525 7960440 Plus 152431-153243
403534 8076917 Minus 46652-47332
403568 8101145 Minus 85509-85658
403572 8101156 Minus 1253-1675
403574 8101156 Plus 5542-6176
403623 8569879 Minus 3519-5426
403625 8569879 Plus 6551-7111
403637 8671936 Minus 142647-142771,145531-145762
403678 7331517 Minus 119573-120430
403691 7387384 Minus 88280-88463 403776 7770611 Minus 1414-1513,1624-1756
403780 8076989 Plus 93160-93409
403786 8083636 Minus 73028-73217
403891 7331467 Minus 191508-193220
403937 7711761 Minus 12609-12773
404042 9558573 Plus 51405208,8633-8763
404043 9558573 Plus 29042-29135,46597-46699
404068 3168621 Minus 18123-18766
404108 8247074 Minus 6360364942
404166 7596822 Plus 86147-86509
404193 3881948 Minus 94185-94322
404196 3805917 Minus 67928-68109
404249 8655533 Plus 64270-64633
404367 9965011 Minus 114391-114628
404404 7272262 Plus 82112-82244
404414 7382165 Pius 143127-143398
404416 7382420 Minus 143042-143216,144704-144853,145800-146048
404420 7407952 Minus 129817-130586
404443 7579073 Minus 87198-87441
404453 7657714 Plus 27768-29179
404476 8080699 Plus 101841-102043
404518 8151988 Plus 84494-84603
404526 8152087 Plus 121918-122123,125198-125348
404531 8247909 Plus 20152-20362
404561 9795980 Minuε 69039-70100
404569 7249169 Minus 104257-104348,104822-104970
404582 9739220 Plus 53230-53424
404587 8698840 Minus 69781-70096
404588 6456726 Minus 40059-40210
404593 9944086 Minus 74922-75788
404595 9958262 Minus 16764-16900
404638 9796751 Minus 99433-99528,100035-100161
404652 9796969 Minus 108172-108296
404694 9799957 Minus 128092-128227
404708 9800828 Plus 77522-77658
404731 7230299 Minus 168609-168781,182951-183081
404767 7882827 Minus 23244-23759
404793 7232206 Minus 61087-61590
404822 3810614 Plus 7541-8132
404834 6911603 Minus 37948-38226
404957 7407927 Plus 147512-148011
404967 7523744 Minus 89944-90729
404988 4662677 Minus 72406-72600,72779-72856
405001 6015406 Minus 104646-104819
405008 6088019 Minus 64091-64267
405090 8072525 Minus 38552-39202
405120 8099940 Plus 140176-140340
405229 7249019 Plus 51081-51701
405230 7249032 Minus 97493-97682
405302 2078453 Minus 121688-121840
405347 2979602 Minus 977-1116
405443 7408143 Pluε 90716-90887,101420-101577
405455 7656675 Plus 134112-134671
405456 7656676 Plus 150052-150208
405494 8050952 Minuε 70284-70518
405521 9454643 Pluε 65096-65247,77508-77637,81242-81364,84246-84395
405523 9454643 Plus 114550-114688,117265-117407,119490-119599,123237-123395,131140-131217
405605 5836195 Minus 117070-117270
405608 5815499 Minus 66822-66925
405634 5306288 Plus 17856-17957,18302-18412,18837-18927,22790-22989
405654 4895155 Minus 53624-53759
405692 4314424 Plus 61379-62562
405738 9943998 Plus 44370-45410
405747 8469069 Minus 153933-154060
405780 7248203 Minus 48204-48371
405783 5738434 Minus 27238-27885
405784 7417368 Minus 77798-78000
405829 7109593 Minus 15628-16127
405920 6758795 Plus 120621-120971
405935 6758795 Minus 163112-163652
405970 8247789 Minus 45795-46295
406005 8247801 Minus 39912-40220
406018 6758904 Minus 37795-38168
406076 9123123 Plus 89972-90319
406092 9123919 Plus 251370251797,252168-252882
406190 7289992 Minus 22395-22901
406288 7549620 Plus 111718-112008
406298 5686278 Minus 30084-30770
406333 9213235 Plus 64689-64798
406364 9256114 Minus 50715-50833
406378 9256142 Minus 126408126800
406413 9256407 Pluε 4385844003,46993-47136
406468 9795553 Plus 4373-4616,8870-9046,11366-11509,1162511880 406603 8272659 Minus 39506 39694
TABLE 31 A ABOUT 1884 GENES UP-REGULATED IN IPF COMPARED TO NSIP
Table 31A lists about 1884 geneswhose expression levels are up regulated in idiopathic pulmonary fibrosis (IPF) samples as compared with non-specific interstitial pneumonia (NSIP) samples These were selected from about 59680 probesets on an Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" idiopathic pulmonary fibrosiε εample expreεsion level to "average" non specific interstitial pneumonia sample expression was greater than or equal to about 20 The "average" idiopathic pulmonary fibrosiε level waε set to the 90th percentile amongst idiopathic pulmonary fibrosis samples The "average" non specific interstitial pneumonia level was set to the 90th percentile amongst non specific interstitial pneumonia samples
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accesεion number UnigenelD Unigene number
Unigene Title Unigene gene title R1 Ratio oflPF (idiopahic pulmonary fibrosis) to NSIP (non specific interstitial pneumonia)
Pkey ExAccn Unigene ID Unigene Title R1
450478 AW451709 Hs 271200 ESTs 202
405654 161
432365 AK001106 Hs 274419 hypothetical protein FLJ 10244 119
403637 112
431548 AI834273 Hs 9711 novel protein 108
407811 AW190902 Hs 40098 cysteine knot superfamily 1, BMP antagon 104
439606 W79123 Hs 58561 G protein coupled receptor 87 103
403574 101
416653 AA768553 Hs 74170 metallot ionein 1E (functional) 93
441233 AA972965 Hs 135568 ESTs 91
415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t
409632 W74001 Hs 55279 serine (or cysteine) proteinase inhibito 84
432437 W07088 Hs 293685 ESTs 83
407266 AJ235664 gb Homo sapienε mRNA for immunoglobulin 82
423017 AW178761 Hs 227948 senne (or cysteine) proteinase inhibito 81
403329 80
429629 BE501732 Hs 30622 Homo sapiens cDNA FLJ13010 fis, clone NT 80
441519 AA972740 Hs 127092 ESTs 79
453823 AL137967 gb DKFZp761D2315_r1 761 (synonym hamy2) 78
406690 M29540 Hs 220529 carcmoembryonie antigen related cell ad 77
416379 N38857 Hs 203933 ESTs 77
428862 NM 000346 Hs 2316 SRY (sex determining region Y)-box 9 (ca 75
407305 AA715284 gb nv35f03 r1 NCI CGAP Br5 Homo sapiens 72
434683 AW298724 Hs 202639 ESTs 72
441802 AA968636 Hs 127877 ESTs 69
431242 AA987742 Hs 251278 KIAA1201 protein 69
442377 AA993807 Hs 167367 ESTs 69
420407 AA814732 Hε 145010 lipopolysaccaπde-specific response 5-lι 68
428908 AW303529 Hε 144955 ESTs 68
445898 AF070623 Hs 13423 Homo sapiens clone 24468 mRNA sequence 67
457673 AA551569 Hs 272034 hypothetical protein PR02822 67
458771 AW295151 Hs 163612 ESTs 66
426800 AA385085 gb EST98959 Thyroid Homo sapiens cDNA 5' 66
440504 AI948966 Hs 130017 ESTs, Weakly similar to JN0908 H- ransp 66
415025 AW207091 Hs 72307 ESTs 65
438557 AW364104 Hε 143509 hypothetical protein FU21924 65
416128 AA173632 Hs 22116 CDC14 (cell division cycle 14, S cerevi 64
457242 AA457011 gb aa90c11 r1 Stratagene fetal retina 93 63
423629 AW021173 Hs 18612 Homo sapienε cDNA FLJ21909 fis, clone H 63
404793 62
435563 AF210317 Hs 95497 solute camerfamily 2 (facilitated glu 62
415672 N53097 Hs 193579 ESTs 62
455488 AA102322 gb zl90f03 r1 Stratagene colon (937204) 62
426230 AA367019 Hs 241395 protease, seπne, 1 (trypsin 1) 61
412282 BE160188 gb QV1-HT0413-010200-059-g05 HT0413 Homo 61
431622 AW979271 Hs 293184 ESTs 61
405523 60
424693 BE169810 Hs 47557 ESTs 60
436397 AA715013 Hs 169835 ESTs 60
456476 AA256753 gb .s22b12 r1 NCI CGAP GCB1 Homo sapiens 59
434784 AA649051 Hs 164007 ESTs 59
422977 AA631498 gb np83h04 s1 NCI CGAP Thy1 Homo sapiens 59
442849 R10099 Hs 269805 ESTs 59
451519 AI800600 Hs 209573 ESTs 58
412474 AI791451 gb nι50c09 y5 NCI_CGAP_Ov2 Homo εapienε 58
457081 AA916785 Hs 180610 splicing factor proline/glutamme rich ( 58
444827 R09764 Hs 20416 ESTε 58
404822 57
402430 57
457900 AW976692 Hs 291665 ESTε 57
400292 AA250737 Hs 72472 ESTε 57
410934 AW811114 gb MR2-ST0131-111199 016-a04 ST0131 Homo 57
440172 AA868584 Hs 126154 ESTs 57 431374 BE258532 Hs 251871 CTP synthase 57
409816 AW500954 gb UI HF-BPOp-air-h 12 0 UI r1 NIH_MGC_5 56
447613 AL041057 Hs 33363 DKFZP434N093 protein 56
417919 AI928203 Hs 86379 ESTs 56
425259 AL049280 Hs 155397 Homo sapiens mRNA, cDNA DKFZp564K143 (fr 56
439063 AF085922 Hs 113968 ESTs 56
406053 55
431211 M86849 Hs 323733 gap junction protein, beta 2, 26kD (conn 55
451830 H18433 Hs 21542 KIAA1035 protein 55
416035 H42314 gb yo09e02 s1 Soares adult brain N2b5HB5 55
413849 BE173561 Hs 15384 APΪ gamma subunit binding protein 1 55
459458 AW270957 Hs 254577 ESTs, Weakly similar to B34087 hypotheti 55
416154 Z46122 gb HSC0VB031 normalized infant brain cDN 55
404561 54
428895 AA437124 Hs 187247 ESTs 54
419247 S65791 Hs 89764 fragile X mental retardation 1 54
455601 AI368680 Hs 816 SRY (sex determining region Y) box 2 54
440925 AW511090 Hε 130419 ESTε 54
419249 X14767 Hs 89768 gamma aminobutyπc acid (GABA) A recepto 54
448477 BE612572 gb 601452090F1 NIH MGC 66 Homo εapienε c 54
454039 AW079064 Hs 245540 ESTs 53
459664 53
401497 53
408493 BE206854 Hs 46039 phosphoglycerate mutase 2 (muscle) 53
444931 AV652066 Hs 75113 general tranεcπption factor IIIA 53
456680 AL137758 Hs 116072 Homo εapiens mRNA, cDNA DKFZp434H245 (fr 53
452542 AW812256 gb RCO ST0174-191099 031-a07 ST0174 Homo 52
411402 BE297855 Hs 69855 NRAS related gene 52
404957 52
436445 AA922213 Hs 121735 ESTs 52
442617 AW340093 Hs 130538 ESTs 52
416045 H15990 Hs 31403 ESTs 52
425178 H16097 Hs 161027 ESTs 52
441918 AI733373 Hs 128119 ESTs 52
455464 AW983901 gb RC1-HN0003 220300 011410 HN0003 Homo 52
420929 AI694143 Hs 296251 programmed cell death 4 52
448844 AI581519 Hs 177164 ESTs 52
430686 NM.001942 Hs 2633 desmoglein 1 52
405229 51
417641 AA205015 Hs 54617 hypothetical protein FLJ20060 51
434167 AA626334 Hs 116153 ESTs 51
450438 AI696071 Hs 253800 ESTs 51
456394 W28506 gb 48f1 Human retina cDNA randomly pπme 50
455747 BE074910 gb RC5-BT0580 170300 021-F12 BT0580 Homo 50
417420 T85150 Hs 268814 ESTs 50
409545 BE296182 Hs 19002 hypothetical protein MGC4675 50
426750 AA383950 gb EST97403 Thymus II Homo sapiens cDNA 50
440615 AI733055 Hs 130806 ESTs 50
408959 AW890878 Hs 211610 CUG triplet repeat, RNA-binding protein 49
454482 BE147919 gb RC3-HT0230-160200-016-a08 HT0230 Homo 49
436508 AW604381 Hs 121121 ESTs, Weakly similar to S00755 pleckstπ 49
452046 AB018345 Hs 27657 KIAA0802 protein 49
407415 AF073328 gb Homo εapiens tetracyline transporter- 49
450090 AW448940 Hs 202259 ESTε 49
406333 49
434188 AI765848 Hs 281680 peroxisomal trans 2-eπoyl CoA reductase, 48 403344 48
446466 H38026 Hs 308 arrestin 3, retinal (X-aπestiπ) 48 405455 48
411387 AW842339 Hs 130815 hypothetical protein FLJ21870 48
426097 BE327369 Hs 112238 ESTs 48
427768 T78402 Hs 174880 ESTs 48
411018 AW813428 gb MR3-ST0192-010200-210-C05 ST0192 Homo 48
415257 F03016 Hs 27513 ESTs 48
441107 AA917075 Hs 190520 ESTs 48
419519 AI198719 Hs 176376 ESTs 48
410901 AW810001 gb MR4-ST0124-270300 005-b11 ST0124 Homo
426217 AW131888 Hs 172792 ESTs, Weakly similar to hypothetical pro 48
424188 AW954552 Hs 142634 zinc linger protein 48
456987 AI557290 Hs 173536 ESTs 48
405303 48
414955 C15506 gb C15506 Clontech human aorta polyA+mR 48
451620 AW449888 Hs 257224 ESTs 47
421948 L42583 Hs 334309 keratin 6A 47
424780 U39576 Hs 153058 butyrophiliπ, subfamily 1, member A1 47
443271 BE568568 Hs 195704 ESTs 47
417181 L10123 Hs 1071 surfactant protein A binding protein 47 402230 47
422246 AA461032 Hs 5306 hypothetical protein DKFZp586F1122 sιmιl 47
431508 NM 012481 Hs 182979 πbosomal protein L12 47
415236 R41400 gb yf94b12 si Soares infant brain 1NIB H 47
413101 BE065215 gb RC1 -BT0314-310300-015 f01 BT0314 Homo 46
444774 AW052174 Hs 196030 ESTs 46 444414 AW293214 Hs 8752 transmembrane protein 4 46
431291 N25521 Hs 25275 Kruppel-type zinc finger protein 46
436853 BE328074 Hs 148661 ESTs 46
445334 AI610081 Hs 9475 glucose transporter protein 10 46
408172 W02488 Hs 46039 phosphoglycerate mutase 2 (muscle) 46
426985 BE394849 Hs 131905 ESTs, Moderately similar to Z195.HUMAN Z 46
404638 46
447617 AI400762 Hs 176675 ESTs 46
422182 AL043892 Hs 180582 Homo sapiens cDNA FLJ21836 fis, clone H 46
442360 AI374621 Hε 29055 ESTs 46
411738 AW858353 gb MR1 CT0353 150300-102-a12 CT0353 Homo 45
444157 AI125785 Hε 153351 ESTs 45
401365 45
459592 AL037421 Hε 208746 ESTs, Moderately similar to pot ORF I [ 45
436269 AA707472 Hs 190760 ESTs 45
459448 AA416773 Hs 275012 EST 45
452090 AA022684 Hs 124673 Homo sapienε cDNA FLJ11477 fis, clone HE 45
414899 AW975433 Hs 36288 ESTs 45
443764 F23283 gb HSPD22980 HM3 Homo sapiens cDNA clone 45
444898 AI201548 Hε 308338 ESTs 45
417428 N87579 gb LL2030F Human fetal heart Lambda ZAP 45
428528 AI004034 Hs 98638 ESTs 45
405605 45
457982 AW856093 Hs 183617 ESTs 45
427731 AA411750 Hs 20943 ESTε 44
420691 AA829433 Hs 275343 ESTε 44
429927 NM 001115 Hs 2522 adenylate cyclase 8 (brain) 44
453080 AI423056 Hs 23921 hypothetical protein DKFZp547A023 44
412147 AW895984 gb QV4-NN0039 040500-197-e08 NN0039 Homo 44
435747 AI079519 Hs 134398 ESTs 44
453824 AL138012 Hs 183840 ESTs, Moderately similar to ALU7.HUMAN A 44
458865 T05095 Hs 19597 KIAA1694 protein 44
459037 AW439497 Hs 290656 EST 44
403310 44
425578 U65652 Hs 158313 chromosome 17 open reading frame 1A 44
427500 AW970017 Hs 293948 ESTs, Weakly similar to S65657 alpha-1 C- 44
432020 AJ251509 Hs 272345 phospfιodιesterase 11A 44
453043 AW136440 Hs 224277 ESTs 44
456293 AW131715 Hs 311561 ESTs, Weakly similar to CYA7.HUMAN ADENY 44
447879 BE503405 Hε 170437 ESTs, Weakly similar to PRP4 HUMAN SALIV 44
426646 AA382787 Hs 122713 ESTs 44
454864 AW835775 gb QV4-LT0016-240200 110-d04 LT0016 Homo 44
404898 44
435434 AA680387 Hε 187850 ESTs 44
443314 AW771701 Hs 54646 ESTs 43
408000 L11690 Hs 620 bullous pemphigoid antigen 1 (230/240kD) 43
441700 AA233556 Hε 126908 hypothetical protein FLJ 12994 43
455000 AW850283 Hs 324429 Homo sapiens cDNA FLJ14015 fis, clone HE 43
404767 43
445189 AI936450 Hs 147482 ESTs 43
452393 H87398 Hs 99858 πbosomal protein L7a 43
428740 AA433838 gb zw53e12 r1 Soares_total_fetus_Nb2HF8_ 43
426830 AA385751 Hs 196379 ESTs, Weakly similar to putative p150 [H 43
410615 AW772721 gb hl95c01 x1 NCI.CGAP.Thy8 Homo sapienε 43
446619 AU076643 Hs 313 εecreted phosphoprotein 1 (osteopontin, 43
406073 43
405692 43
436033 H75391 Hs 255748 ESTε 43
410733 D84284 Hs 66052 CD38 antigen (p45) 43
455587 BE007829 gb QV0-BN0147-280400-213-d03 BN0147 Homo 43
459084 H01699 Hs 27289 CGI-125 protein 43
401189 43
435451 AF195420 Hs 303006 ESTε, Weakly similar to gamma-heregulm 43
456407 AW968614 gb EST380690 MAGE resequenceε, MAGJ Homo 43
425733 F13287 Hs 159388 Homo sapiens clone 23578 mRNA sequence 43
447863 AL047611 Hs 288885 Homo εapienε cDNA FLJ14246 fis, clone OV 43
436659 AI217900 Hs 144464 ESTs 43
435463 AA682507 gb zj18f08 s1 Soareε fetal liver εpleen 43
455675 BE065984 gb RC3-BT0319-120200-014-a06 BT0319 Homo 43
439481 AF086294 Hs 125844 ESTε 43
405287 43
405784 43
436461 AW511956 Hs 293261 ESTε 43
437636 AA764781 Hs 291844 ESTs 42
409629 AW449589 Hs 279724 ESTs 42
412999 BE046255 gb hπ38g10 x2 NCI.CGAP.RDF2 Homo εapienε 42
403281 42
427531 AA405097 Hε 97957 ESTε 42
451882 AI821324 Hs 100445 ESTs 42
418856 AA362858 gb EST72900 Ovary II Homo sapiens cDNA 5 42
405494 42
456027 BE327387 Hs 13913 KIAA1577 protein 42
414539 BE379046 gb 601236646F1 NIH_MGC_44 Homo sapiens c 42 421106 AA877124 Hs 172844 ESTs 42
408076 N57559 Hs 82273 hypothetical protein 42
418563 AA526235 Hs 193162 Homo sapiens cDNA FLJ11983 fis, clone HE 42
411688 AW953440 gb EST365510 MAGE resequences, MAGB Homo 41
416614 T83391 Hs 111849 ESTs 41
454434 AA083558 Hs 261286 ESTs 41
404526 AI912555 Hs 157195 peptide YY, 2 (semtnalplasmm) 41
446383 AW014174 Hs 301956 zinc finger protein 41
405302 41
432668 AL043482 Hs 267115 ESTs 41
416972 BE019670 gb bb28c01 x1 NIH MGC 5 Homo εapiens cDN 41
423841 AW753967 gb RC2-CT0304-080100 011-M2 CT0304 Homo 41
427099 AB032953 Hs 173560 odd Oz/ten m homolog 2 (Drosophila mous 41
430484 D82880 Hs 241548 RAS p21 protein activator 2 41
403895 41
420457 AA482280 Hs 191656 ESTs 41
438993 AA828995 gb od77b08 s1 NCI CGAP Ov2 Homo sapiens 41
458421 AI279978 Hs 22547 ESTs 41
458722 AA741545 Hs 282832 ESTs, Weakly similar to T24961 hypotheti 41
411382 BE067246 gb PM1-BT0348-151299 001-d04 BT0348 Homo 41
422373 AK001843 Hs 115700 Homo sapienε cDNA FLJ23515 fis, clone L 41
430749 AJ242956 Hs 25960 v yc avian myelocytomatosis viral relat 41
403625 41
401887 41
403667 41
452744 AI267652 Hs 30504 Homo sapiens mRNA, cDNA DKFZp434E082 (fr 40
421065 AA329711 gb EST33382 Embryo, 12 week II Homo sapi 40
439294 AW975328 Hs 6523 chromosome 1 open reading frame 12 40
432792 AA448114 Hs 278950 protocadhenn beta 1 40
405443 40
431169 AW971240 gb EST383329 MAGE resequences, MAGL Homo 40
431822 AA516049 gb ng65d01 s1 NCI_CGAP_Lιp2 Homo sapiens 40
432328 AI572739 Hs 195471 6-phosphofructo-2-kιnaεe/fructoεe-2,6 bι 40
448324 AI571356 Hs 34174 ESTε, Moderately εimilar to ALU8 HUMAN A 40
456536 AW135986 Hs 257859 ESTs 40
415811 AA450191 Hs 172963 hypothetical protein FLJ 14624 40
411745 AW867826 gb MRO-SN0039-300300 001-c02 SN0039 Homo 40
438660 U95740 Hs 6349 Homo sapiens, clone IMAGE 3010666, mRNA, 40
449327 AI638743 Hs 224672 ESTs 40
426062 N57014 Hs 75874 pregnancy-associated plasma protein A 40
433485 AI493076 Hs 201967 aldo keto reductase family 1, member C2 40
434849 AW292765 Hs 8053 ESTs 40
400268 40
422728 AW937826 Hs 103262 ESTs, Weakly similar to ZN91 HUMAN ZINC 40
445414 AV653692 Hs 146105 ESTs 40
406470 39
429809 AL162010 Hs 223603 Homo sapiens mRNA, cDNA DKFZp761D09121 ( 39
453098 Z25935 Hs 86379 ESTs 39
402867 39
431071 AA491379 gb aa65f05 r1 NCI CGAP GCB1 Homo sapiens 39
436298 AW293496 Hs 180138 ESTs 39
440356 AI933184 Hs 127922 ESTs, Moderately similar to S65657 alpha 39
419091 T85332 Hs 178294 ESTs 39
422591 L07648 Hs 118630 MAX-interacting protein 1 39
426076 AW962714 gb EST374787 MAGE resequences, MAGG Homo 39
443682 AI383061 Hs 47248 ESTs, Highly similar to similar to Cdc14 39
444461 R53734 Hs 25978 ESTε, Weakly similar to 2109260A B cell 39
430072 X13294 Hs 300592 v myb avian myeloblastosiε viral oncogen 39
413499 BE144884 gb CM0-HT0182-041099-065-e11 HT0182 Homo 39
439818 AL360137 Hs 19934 Homo εapienε mRNA full length insert cDN 39
443323 BE560621 Hs 9222 estrogen receptor binding site associate 39
424029 AB014594 Hs 137579 KIAA0694 gene product 39
455993 BE179085 gb RCO HT0613-140300-021-d06 HT0613 Homo 39
420111 AA255652 gb zs21h11 ri NCI_CGAP_GCB1 Homo εapieπs 39
403956 W28077 Hs 79389 nel (chιcken)-lιke 2 39
410318 AA084050 Hs 269259 ESTs, Weakly similar to S23650 retroviru 39
426497 AA379913 gb EST92807 Skin tumor I Homo sapiens cD 39
430140 AW296771 Hs 221999 ESTs 38
457042 AI382130 Hs 97703 ESTs 38
450236 AW162998 Hs 24684 KIAA1376 protein 38
417706 T90797 Hs 268623 ESTs 38
428692 AI372822 Hs 110103 RNA polymerase I transcnption factor RR 38
413071 BE064032 gb QV3-BT0296-010300-111-b08 BT0296 Homo 38
437354 AA749215 Hs 291886 ESTs 38
403381 38
425798 AA364002 gb EST74529 Pineal gland II Homo sapiens 38
459429 AA278779 Hs 335696 EST 38
426365 AA376667 Hs 10283 RNA binding motif protein 8B 38
430757 AI458623 gb tk04g09 x1 NCI_CGAP_Lu24 Homo sapiens 38
430205 AB025904 Hs 235168 carbonic anhydrase XIV 38
433887 AW204232 Hs 279522 ESTs 38
444743 AA045648 Hs 301957 nudix (nucleoside diphosphate linked moi 38
404043 38 431333 AA708488 Hs 120127 Homo sapiens cDNA FLJ22769 fis, clone K 38
451073 AI758905 Hs 206063 ESTs 38
417663 R07483 Hs 180461 ESTs 38
432363 AA534489 gb nf76g11 ε1 NCI CGAP Co3 Homo sapiens 38
436975 AA740723 Hs 212644 ESTs 38
405959 38
400631 AF173937 Hs 109494 secreted protein of unknown function 37
425937 NM 013240 Hs 163846 putative N6 DNA methyltransferase 37
446158 A1277603 Hs 145990 ESTs, Weakly similar to I38022 hypotheti 37
450375 AA009647 Hs 8850 a disintegnn and metalloproteinase doma 37
416548 H62953 gb yr47f06 r1 Soares fetal liver spleen 37
436020 AA778177 Hs 121724 ESTs 37
424989 AA985520 Hs 23575 ESTs 37
426447 AV655843 Hs 169919 electroπ-transfer-flavoprotein, alpha po 37
441416 AI9S0139 Hs 148609 ESTs 37
456443 AW967500 Hs 133543 ESTs 37
402112 R58624 Hs 2186 eukaryotic translation elongation factor 37
404453 37
451421 W16522 Hs 237689 Homo sapiens cDNA FLJ13539 fis, clone PL 37
421037 AI684808 Hs 197653 ESTs 37
427088 AA398085 Hs 142390 ESTε 37
453375 AI99011 Hs 240091 ESTs 37
453530 AW021633 gb df26c02 y1 Morton Fetal Cochlea Homo 37
406964 M21305 gb Human alpha satellite and satellite 3 37
432291 AK001108 Hs 274274 hypothetical protein FLJ 10246 37
449623 C00719 Hs 120440 EST 37
419691 W03298 Hs 193521 ESTs 37
437587 AI591222 Hs 72325 Human DNA sequence from clone RP1-187J11 37
403271 37
453123 AI953718 Hs 221849 ESTε 37
400462 37
449804 AI535663 Hs 39379 ESTs 37
443305 AI050693 Hs 133318 ESTs 37
411186 AW821257 gb PM3-ST0307-2312990014)11 ST0307 Homo 36
424565 AW102723 Hs 75295 guanylate cyclase 1, soluble, alpha 3 36
432189 AA527941 gb nh30c04 s1 NCI_CGAP_Pr3 Homo sapiens 36
403296 36
417918 AA209205 Hs 163754 hypothetical protein FLJ 12606 36
436026 AI349764 Hs 217081 ESTs 36
429864 AA460039 Hs 286 πbosomal protein L4 36
418592 X99226 Hs 284153 Fanconi anemia, complementation group A 36
442910 AI365130 Hε 11307 ESTs, Weakly similar to T19326 hypotheti 36
446304 AW104432 Hs 149761 ESTs 36
441216 BE299830 Hs 192908 ESTs 36
421494 AI763322 Hs 152104 ESTs 36
404476 36
416327 R99822 Hs 36172 ESTs 36
414146 BE549372 Hs 317596 Homo sapienε cDNA FLJ12927 fiε, clone NT 36
417401 AA426026 Hs 187615 ESTε 36
401200 36
411560 AW851186 Hs 179909 hypothetical protein FLJ22995 36
426306 AA447310 Hs 164059 Homo sapiens cDNA FLJ13338 fis, clone OV 36
437918 AI761449 Hs 121629 ESTs 36
447917 AL048037 Hε 164588 ESTε, Moderately similar to neuronal thr 36
421328 BE466506 Hε 3981 ESTε 36
447290 AI476732 Hε 263912 ESTε 36
417229 AA975096 Hs 19522 hypothetical protein PR02849 36
425403 AL023753 Hs 156406 Human DNA sequence from clone 1198H6 on 36
403515 36
419917 AA320068 Hs 93701 Homo sapiens mRNA, cDNA DKFZp434E232 (fr 36
435554 AF208502 Hs 185708 early B-cell factor 36
420481 U50525 Hs 98201 Human BRCA2 region, mRNA sequence CG029 36
410500 R09442 gb yf26c09 r1 Soares fetal liver spleen 36
439326 W07140 Hs 54721 ESTs 36
426296 R14454 Hs 5921 Homo sapienε cDNA FU21592 fis, clone C 36
411311 AW836491 gb PM3-LT0032-281299002402 LT0032 Homo 36
418019 R68911 Hs 176275 ESTs 36
417490 AA203335 gb zx56g02 r1 Soares.fetal. ver.εpleen. 36
423035 AW449679 Hs 156739 H sapiens XG mRNA (clone PEP11) 36
416575 W02414 Hs 38383 ESTs 35
414400 X06948 Hs 897 Fc fragment of IgE, high affinity I, rec 35
418405 AI868282 Hs 11898 ESTs, Highly similarto KIAA1370 protein 35
450350 T97817 Hs 174880 ESTs 35
451704 AI755209 Hs 205616 ESTs, Weakly similar to ALULHUMAN ALU S 35
421013 M62397 Hs 1345 mutated in colorectal cancers 35
407404 AF040257 gb Homo sapienε TNF receptor homolog mRN 35
423121 AW864848 gb PM2-SN0018290300-003-c09 SN0018 Homo 35
430533 AA480895 Hε 201552 ESTs, Weakly similar to T17288 hypotheti 35
457141 AA521410 Hs 41371 ESTs 35
411772 BE170301 gb QV4-HT0536-040500 193-105 HT0536 Homo 35
440737 AI375167 Hs 132221 hypothetical protein FLJ12401 35
452728 AI915676 Hs 239708 ESTs 35
423266 AA323875 Hs 193574 ESTs 35 413543 AA130228 Hs 324611 ESTs, Moderately similar to ALU8 HUMAN A 35
454447 BE163567 gb QV3 HT0460 230200-101-b08 HT0460 Homo 35
458067 AA393603 Hs 36752 protein kinase anchoπng protein GKAP42 35
437608 AA761605 Hs 292308 ESTs, Weakly similar to ALULHUMAN ALU S 35
415549 F11942 gb HSC33F061 normalized infant brain cDN 35
420910 AL049437 Hs 100292 Homo sapiens mRNA, cDNA DKFZp586E1120 (f 35
435793 AB037734 Hs 4993 KIAA1313 protein 35
453211 W84829 gb zh53f04 r1 Soares fetal liver spleen 35
418717 AI334430 Hs 86984 ESTs 35
400641 35
442973 BE567665 Hs 288550 Homo εapiens cDNA FLJ23156 fis, clone L 35
418007 M13509 Hs 83169 matrix metalloproteinase 1 (mterεtitial 35
440364 AA910460 Hs 128626 ESTs 35
458340 AI457102 Hs 6986 Human glucose transporter pseudogene 35
412281 AI810054 Hs 14119 ESTs 35
443204 AW205878 Hs 29643 Homo sapienε cDNA FLJ13103 fiε, clone NT 35
416616 H68270 gb yr81h09 r1 Soares fetal liver spleen 35
444338 AI937026 Hs 146642 ESTε 34
436946 AW137748 Hs 125956 ESTε 34
431632 AK000992 Hs 333144 Homo sapiens cDNA FLJ10130 fis, clone HE 34
403306 NM 006825 Hs 74368 transmembrane protein (63kD), endoplasmi 34
422093 AF151852 Hs 111449 CGI-94 protein 34
428816 AA004986 Hs 193852 ATP-binding cassette, sub family C (CFTR 34
442137 AA977235 Hε 128830 ESTs Weakly similar to Z192.HUMAN ZINC 34
405970 34
409434 AF278761 Hs 131581 Homo sapienε teεtiε transcript Y 7 (TTY7 34
416100 H18700 Hs 268799 ESTs 34
431418 X68242 Hs 252722 Hιn-1 34
431954 AK001974 Hs 272242 hypothetical protein FLJ11112 34
440388 AI693520 Hs 223000 ESTs 34
421072 AI215069 Hs 89113 ESTs 34
424578 AK001973 Hs 150890 hypothetical protein 34
436331 AI239495 Hs 120189 ESTs 34
444063 AI122614 gb qa96b05 1 Soares fetal_heart_NbHH19W 34
444453 AW379394 Hε 145126 ESTs 34
404196 34
421262 AA286746 Hε 9343 Homo sapiens cDNA FLJ 14265 fis, clone PL 34
409555 AW410788 Hs 256185 ESTs 34
417669 T99898 gb ye68g01 rl Soares fetal liver spleen 34
416057 AI927382 Hs 29857 ESTs 34
425206 NM 002153 Hs 155109 hydroxysteroid (17-beta) dehydrogenase 2 34
447738 AI871000 Hs 161330 ESTs 34
430664 AW969834 Hs 303303 ESTs 34
411377 AW841462 gb RC6-CN0014-080300-012-B09 CN0014 Homo 34
415769 H94186 Hs 5912 F-box only protein 7 34
429382 AI791249 Hs 278054 ESTs, Weakly similar to I38022 hypotheti 34
431474 AL133990 Hs 190642 ESTs 34
456908 AI953671 Hs 220994 hypothetical protein FLJ 14129 34
442826 AI018777 Hs 131241 ESTs 34
400608 34
436111 AI803082 Hs 157212 ESTs 34
452807 AA028933 Hs 162434 ESTs 34
436577 W84774 Hs 17643 ESTs 34
412209 AW901456 gb RCO-NN1012-270300-031-C07 NN1012 Homo 34
417153 X57010 Hs 81343 collagen, type II, alpha 1 (pnmary oste 34
423871 AA331906 gb EST35805 Embryo, 8 week I Homo sapien 34
447516 W05355 Hs 102971 hypothetical protein FU14751 34
409623 AW449185 gb UI-H-BI3-akg-e-05-0-UI ε1 NCI_CGAP_Su 34
416182 NM.004354 Hs 79069 cyclin G2 34
420854 AW296927 gb UI-H-BWO-ajc-c 07-0-UI s1 NCI_CGAP_Su 34
422899 D16471 Hs 121571 Human mRNA, Xq terminal portion 34
432404 AA535246 Hs 50852 ESTs 34
458695 AV660159 Hs 282284 ESTs, Weakly similar to I38022 hypotheti 34
440727 AI073991 Hs 134268 ESTs, Weakly similar to 2109260A B cell 33
428766 AA477989 Hs 98800 ESTs 33
439567 AI056618 Hs 134314 ESTs 33
456231 H73183 Hs 129885 ESTs, Weakly similar to 2004399A chromos 33
454318 AW367764 Hs 7857 erythrocyte membrane protein band 4 1-lι 33
411966 AA099113 Hs 118609 ESTs 33
443644 AI080491 Hs 93270 ESTs, Moderately similar to S65657 alpha 33
437037 T63804 gb yc21e09 Stratagene lung (937210) H 33
407664 AW063476 Hs 279080 ESTs 33
405780 33
426567 AA381579 Hs 182962 ESTs 33
400432 AX015809 Hs 287767 Sequence 8 from Patent WO9950285 33
403356 33
404518 AI815601 Hs 79197 CD83 antigen (activated B lymphocytes, i 33
413581 BE150618 gb RC3 HT0272-110100-013-C06 HT0272 Homo 33
429875 AI091815 gb qa58b06 ε1 Soareε NhHMPu S1 Homo sapi 33
433785 BE044593 Hs 112704 ESTs 33
437876 AA770151 Hs 126424 ESTs 33
444870 AI200621 Hs 148504 ESTε 33
453324 W26592 Hs 232089 ESTε 33 437963 BE396279 gb 601309785F1 NIH.MGC.44 Homo sapiens c 33
425361 AA355933 Hs 132221 hypothetical protein FLJ12401 33
408813 AI580090 Hs 48295 RNA helicase family 33
426692 AK001751 Hs 171835 hypothetical protein FLJ10889 33
407456 AJ237589 gb Homo sapiens mRNA for T-box transcπp 33
433183 AF231338 Hs 222024 transcnption factor BMAL2 33
436168 AK000883 Hs 301645 Homo sapiens cDNA FLJ10021 fis, clone HE 33
438456 AA913381 Hs 190513 ESTs 33
453242 T98327 Hs 18343 ESTs 33
415131 D61119 gb HUM158C11B Clontech human fetal brain 33
412040 D86519 Hs 73086 neuropeptide Y receptor Y6 (pseudogene) 33
435070 AI821270 Hs 285643 Homo sapiens cDNA FLJ 14364 fis, clone HE 33
444443 AI149286 Hs 55099 rab6 GTPase activating protein (GAP and 33
434001 AW950905 Hs 3697 serine (or cysteine) proteinase inhibito 33
454145 AA046872 Hs 62798 ESTs 33
405264 33
411849 AW964970 Hs 18861 ESTs, Moderately similar to KIAA1276 pro 33
416816 T71168 Hs 119567 ESTs, Weakly similar to A47582 B-cell gr 33
435325 AI038388 Hs 119309 ESTs 33
440184 AB002297 Hs 7022 dedicator of cytokinesis 3 33
428356 AL046991 Hs 10338 ESTs 33
429216 AI369472 Hs 65407 ESTs 33
429106 AA446612 gb zw85g07 s1 Soares_total_fetuε_Nb2HF8_ 33
405720 33
400889 33
416294 D86980 Hε 79170 KIAA0227 protein 33
422094 AF129535 Hε 272027 F-box only protein 5 33
425374 AI904013 gb MR-BT041-220199-104 BT041 Homo sapien 33
418122 R42778 Hs 22217 Homo sapiens clone IMAGE 32106, mRNA seq 33
427374 AI150033 Hs 143686 ESTs 33
443367 AW071349 Hs 215937 ESTs 33
446645 AI336596 Hs 156294 ESTs 33
457604 AI004397 Hs 334552 Homo sapiens cDNA FLJ14930 fis, clone PL 33
452291 AF015592 Hs 28853 CDC7 (cell division cycle 7, S cerevisi 33
410481 R34107 Hs 321450 pregnancy specific beta 1 glycoprotein 2 33
458885 AA411303 Hs 30022 ESTs, Weakly similar to NAH6.HUMAN SODIU 33
429608 U49250 Hs 210862 T-box, brain, 1 32
437454 AL390159 Hs 269812 Homo sapienε mRNA, cDNA DKFZp761M0415 (f 32
430503 AA533574 Hs 152274 ESTs 32
432839 AA579465 Hε 45207 hypothetical protein KIAA1335 32
421698 T89677 Hs 324323 ESTs 32
412321 AW936913 gb RC1-DT0029-030200 012-108 DT0029 Homo 32
422219 AW978073 Hs 1010 regulator of mitotic spindle assembly 1 32
454962 AW847645 gb IL3-CT0213-280100 056-A04 CT0213 Homo 32
441705 AI087052 Hs 55993 ESTs 32
403619 32
435608 AW183971 Hs 250896 ESTs 32
426701 AI968103 Hs 209461 Homo sapiens cDNA FLJ12836 fis, clone NT 32
401132 32
407764 BE008347 gb CMO-BN0154-080400-325-h04 BN0154 Homo 32
409425 U40462 Hs 54452 zinc finger protein, subfamily 1A, 1 (Ik 32
428004 AA449563 Hs 151393 glutamate-cysteine ligase, catalytic sub 32
443603 BE502601 Hs 134289 ESTs, Weakly similar to KIAA1063 protein 32
419936 AI792788 gb o!91d05 y5 NCI CGAP Kιd5 Homo sapiens 32
455571 BE003714 gb QV3-BN0096-200400-161-a01 BN0096 Homo 32
406592 32
446530 AV658909 Hs 282642 ESTs 32
454466 AA984138 Hs 155101 ATP synthase, H+ transporting, mitochond 32
401449 32
431196 AW974436 Hs 154929 ESTs 32
422183 AA431698 Hs 112794 Human DNA sequence from clone 1068E13 on 32
459459 AA460445 gb zx66h11 r1 Soares_total_fetus_Nb2HF8_ 32
421308 AA687322 Hs 192843 leucine zipper protein FKSG14 32
427335 AA448542 Hs 251677 G antigen 7B 32
455236 AW875972 gb CM3-PT0014-071299 051-b05 PT0014 Homo 32
425156 AA351364 gb EST59099 Infant brain Homo εapiens cD 32
404588 32
413087 BE064655 gb RC1-BT0313-301299 012-c09 BT0313 Homo 32
444910 AI201849 gb qs76g04 x1 NCI_CGAP_Pr28 Homo sapiens 32
426660 NM.002719 Hs 171734 protein phosphatase 2, regulatory subuni 32
438315 R56795 Hs 82419 ESTs 32
425523 AB007948 Hs 158244 KIAA0479 protein 32
419340 AA236590 Hs 87530 ESTs 32
425636 AK001243 Hs 158370 hypothetical protein FLJ10381 32
430553 AW392821 gb CM4-ST0275-021299 053-h09 ST0275 Homo 32
457030 AI301740 Hs 173381 dihydropyπmidinase like 2 32
447375 AI376660 Hs 257822 ESTs 32
408334 AW514652 Hs 321637 ESTs 32
410085 AA428482 Hs 58589 glycogeπin 2 32
410536 N39533 gb yv27d04 ε1 Soares fetal liver spleen 32
448495 AW136516 Hs 208515 ESTs 32
405634 32
431098 AW501465 Hs 249230 πbonuclease L (2,5 oligoisoadenylate 32 421581 U89331 Hε 105932 short stature homeobox 31 440633 AI140686 Hs 263320 ESTs 31 453264 AA034137 Hs 271955 ESTs 31 411656 AW855576 gb CM4-CT0278-221099 027-d01 CT0278 Homo 31 419169 AW851980 Hs 262346 ESTs, Weakly similar to S72482 hypotheti 31 426591 AA431127 Hs 98685 ESTs 31 446966 C01448 Hs 300511 ESTs 31 452401 NM 07115 Hs 29352 tumor necrosis factor, alpha induced pro 31 455170 AW860972 gb QV0-CT0387-180300 167-h07 CT0387 Homo 31 416208 AW291168 Hs 41295 ESTε, Weakly similar to MUC2_HUMAN MUCIN 31 423657 AL045128 Hs 1691 glucan (1,4-alpha ), branching enzyme 1 31 400816 31 410307 AF022913 Hs 62187 phosphatidylmositol glycan, class K 31 440046 AW402306 Hs 6877 hypothetical protein FLJ10483 31 452824 W27643 Hs 73965 splicing factor, argimne/seπne πch 2 31 400315 U46120 Hs 193392 Human expressed unknown mRNA 31 411965 BE467339 Hs 280115 ESTs 31 416316 H58721 Hs 271628 ESTs 31 400613 31 414819 BE177320 Hs 156148 hypothetical protein FLJ13231 31 434833 AF156548 Hs 192969 ESTs Weakly similar to AT1A.HUMAN POTEN 31 418693 A1750878 Hs 87409 thrombospondin 1 31 416258 N45661 Hs 90011 adenylosucciπate synthase 31 405093 31 415273 Z39840 Hs 22229 ESTs 31 450519 AA010066 Hs 224849 Homo sapiens cDNA FLJ12583 fis, clone NT 31 422654 AA314316 Hs 163725 ESTs 31 414605 BE390440 gb 601283601 F1 NIH.MGC.44 Homo sapiens c 31 400441 M15530 Hs 99879 B-cell growth fxtor 1 (12kD) 31 402790 31 438563 AA810665 Hs 134746 ESTs, Weakly similar to A46010 X-linked 31 447524 D80449 Hs 45177 ESTs 31 448835 BE277929 Hs 11081 UBX domain-containing 2 31 415979 H16427 Hs 271501 ESTs, Weakly similar to I54374 gene NF2 31 434479 AI138213 Hs 162035 olfactory receptor, family 52, subfamily 31 426724 AA383623 Hs 293616 ESTs 31 418105 AW937488 Hs 178000 ESTs, Weakly similar to FV1 MOUSE FRIEND 31 405608 31 406506 31 421216 AV649282 Hs 102664 vesicle associated membrane protein 4 31 452755 AW138937 Hs 213436 ESTs, Weakly similar to A34087 hypotheti 31 404288 31 429878 AA460188 Hs 127263 ESTs 31 439834 AI754576 Hs 124523 ESTs 31 454564 AW807573 gb MR1-ST0088-021299 004-g01 ST0088 Homo 31 450491 BE045604 Hs 202301 ESTs 31 409920 BE169746 Hs 12504 likely ortholog of mouse Arkadia 31 400579 31 402953 31 404285 31 426890 AA393167 Hs 41294 ESTs 31 457770 BE065030 Hs 124179 ESTs 31 435477 BE218708 Hs 117270 hypothetical protein FLJ14345 31 436391 AJ227892 Hs 146274 ESTs 31 456083 U46922 Hs 77252 fragile histidine tπad gene 31 416421 AA134006 Hε 79306 eukaryotic translation initiation factor 31 430101 AF110002 Hs 233363 guanylate cyclase activator 1 C 31 449238 AA428229 Hs 331561 muscle specific RING-finger protein 3 31 452605 AW968557 Hs 90012 hypothetical protein FLJ23441 31 456323 AW752389 Hs 87296 Homo sapienε cDNA FLJ20269 fis, clone HE 31 429828 AB019494 Hs 225767 IDN3 protein 31 423454 AL110456 Hs 469 succinate dehydrogenase complex, subunit 31 452762 AW501435 Hs 278582 v-akt munne thymoma viral oncogene homo 31 401344 31 455511 BE144762 gb CMO-HT0180-041099-065-b04 HT0180 Homo 31 455280 AW886156 gb RC5-OT0078-150300-021-E08 OT0078 Homo 31 433132 AB026264 Hs 284245 hypothetical protein IMPACT 31 423600 AI633559 Hs 310359 ESTs 31 427667 AK001279 Hs 180171 Homo sapiens cDNA FLJ10417 fis, clone NT 30 407257 AB006834 gb Homo sapieπε mRNA for HRV Fab N6-VH, 30 457041 AA399018 Hs 250835 ESTε 30 421482 AL135462 Hs 104715 inversin 30 459062 AA059246 Hs 110293 ESTs 30 436475 R58806 Hs 86149 phosphoinositol 3-phoεphate-bιndιng prot 30 411622 AI807894 Hs 47274 Homo sapiens mRNA, cDNA DKFZp564B176 (fr 30 417489 AW953341 Hs 22573 ESTs, Weakly similar to ALULHUMAN ALU S 30 418454 AA315308 Hs 195870 hypothetical protein FLJ14991 30 409699 BE154650 gb PM3 HT0344-071299 003-c08 HT0344 Homo 30 438394 BE379623 Hs 27693 peptidylprolyl isomerase (cyciophilin) I 30 443741 AW451759 Hs 145420 ESTs 30 405090 30 432267 AK000872 Hs 274227 Homo sapiens cDNA FLJ10010 fis clone HE 30 445409 AI949081 Hs 147862 ESTs 30 449347 AV649748 Hs 295901 KIAA0493 protein 30
428301 AW628666 Hs 98440 ESTs Weakly similar to 138022 hypotheti 30
406364 30
418409 AA219332 Hε 120869 ESTs Weakly similar to R107.HUMAN H REV 30
427050 AA397789 Hε 161803 ESTs 30
431778 AL080276 Hs 268562 regulator of G-protein signalling 17 30
448405 AW207634 Hs 170849 ESTs 30
429846 AB023021 Hs 225945 fucosyltransferase 9 (alpha (1,3) fucosy 30
438165 AA779344 Hε 138136 ESTs, Weakly similar to 1510254A LI repe 30
418888 AU076801 Hs 89436 cadhenn 17, LI cadhenn (liver-mtestin 30
418432 M14156 Hs 85112 insulin like growth factor 1 (somatomedi 30
426424 BE081745 Hs 272188 Homo sapiens cDNA FLJ12090 fis clone HE 30
419505 AA243660 Hs 143061 ESTs 30
403743 30
415452 F09134 Hs 12839 ESTs 30
428579 NM 005756 Hs 184942 G protein-coupled receptor 64 30
447046 AA326187 Hs 17170 G protein-coupled receptor 4 30
455851 BE146879 gb QV4-HT0222-261099 014-c11 HT0222 Homo 30
400227 30
436219 AK001695 Hs 146589 hypothetical protein FLJ10701 30
439037 AF075084 gb Homo sapienε full length insert cDNA 30
439683 AI741816 Hs 125897 ESTs 30
431292 AA370141 Hs 2281 chromogranin B (secretogramπ 1) 30
403513 30
425745 U44060 Hs 14427 Homo sapiens cDNA FU21800 fis, clone H 30
440122 AI733011 Hs 127678 ESTs 30
448446 AI521251 Hs 171030 ESTs 30
422563 BE299342 Hs 19348 hypothetical protein FLJ 13119 30
448130 AW271635 Hs 170717 ESTs 30
420288 AW071225 Hs 245556 ESTs 30
428201 AA424158 Hs 206461 ESTs 30
436643 AA757626 Hs 10941 ESTs, Weakly similar to IPP1.HUMAN PROTE 30
448966 AW372914 Hs 86149 phosphomositol 3 phosphate-binding prot 30
404513 30
412074 S74683 Hs 73139 ADP-nbosyltransferase 1 30
407762 AW235638 Hs 29475 ESTs 30
403396 30
436938 AW139680 Hs 161393 ESTs 30
458090 AI282149 Hs 56213 ESTs, Highly similar to FXD3.HUMAN FORKH 30
400706 29
432779 AW979241 gb EST391351 MAGE resequences, MAGP Homo 29
444600 R41398 Hs 6996 ESTs 29
403786 29
430187 AI799909 Hε 158989 ESTs 29
451700 AI470262 Hs 29553 ESTs 29
456649 R74441 Hs 117176 poly(A) binding protein, nuclear 1 29
457503 AW970244 Hε 162188 ESTs 29
446251 AW867156 Hs 282589 ESTs, Weakly similar to I38022 hypotheti 29
406327 29
434671 R34758 gb yg61g02 r1 Soares infant brain 1NIB H 29
430175 AA468724 gb ne09a06 s1 NCI CGAP Co3 Homo sapienε 29
454186 BE141030 gb MR0-HT0067-201099-002-h11 HT0067 Homo 29
449459 BE546846 Hs 195048 ESTs 29
435934 R19382 Hs 117869 ESTs 29
400325 M85292 Hs 247924 Homo sapiens endogenous HIV-1 related se 29
408408 AF070571 Hs 44690 Homo sapiens clone 24739 mRNA sequence 29
414514 BE327365 Hs 280187 ESTs 29
423717 AA330036 Hs 152003 ESTs 29
424152 AL133591 Hs 141480 Homo sapienε mRNA, cDNA DKFZp434N079 (fr 29
430982 R17432 Hs 22217 Homo sapiens clone IMAGE 32106, mRNA seq 29
424726 AK001007 Hs 138760 Homo sapiens cDNA FLJ10145 fis, clone HE 29
456186 W26642 gb 34b8 Human retina cDNA randomly pπme 29
412222 AA528283 Hs 292737 ESTs 29
459201 AW391177 gb MR3-ST0203-221299 023-d05 ST0203 Homo 29
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 29
435579 AI332373 Hs 156924 ESTs 29
417027 AA192306 Hs 23926 tnadin 29
415533 T74009 Hs 268738 ESTs, Weakly similar to ALU7.HUMAN ALU S 29
445909 BE262656 Hs 32603 hypothetical protein MGC3279 εimilar to 29
418343 AA216372 Hs 159501 ESTε 29
459440 BE048054 gb tz46c03 y1 NCI_CGAP_Brn52 Homo εapien 29
403341 29
445635 AI769774 Hs 209831 ESTε, Weakly similar to ALU1 HUMAN ALU S 29
453830 AA534296 Hs 20953 ESTs 29
455866 BE149024 gb CM0-HT0249 291099-084-c04 HT0249 Homo 29
407676 AW064111 Hs 279823 ESTs 29
437913 AI140825 Hs 121623 ESTs 29
443458 R05385 Hs 143509 hypothetical protein FLJ21924 29
457049 AW631495 Hs 27135 B-cell receptor-associated protein BAP29 29
400491 H25530 Hs 50868 solute earner family 22 (organic cation 29
456189 H91010 Hs 44940 ESTs 29
441874 AA970389 Hs 128055 ESTs 29
416483 H58311 Hs 165077 ESTs 29 420879 N31165 Hs 238837 ESTs, Weakly similar to S43603 RNA bindi 29
446447 AI300402 Hs 202250 ESTs 29
439953 AA918129 Hs 124638 ESTs 29
400643 29
436594 AI419982 Hs 156189 ESTs 29
438402 D16902 Hs 42915 ARP2 (adm related protein 2, yeast) ho 29
451353 N21043 Hs 42932 ESTs 29
419791 AI579909 Hs 105104 ESTs 29
415628 F13080 gb HSC3ID041 normalized infant brain cDN 29
423637 AL137279 Hs 130187 Homo sapiens mRNA, cDNA DKFZp43401214 (f 29
454747 AW818535 gb RC1-ST0278-140300 016 f05 ST0278 Homo 29
452778 R71338 Hs 5921 Homo sapiens cDNA FLJ21592 fis, clone C 29
457178 AL039101 Hs 194625 dynein, cytoplasmic, light intermediate 29
401526 29
408751 N91553 Hs 258343 ESTs 29
414140 AA281279 Hs 23317 hypothetical protein FLJ 14681 29
417320 AA195667 Hs 86022 ESTs 29
442927 AI024347 Hs 131519 ESTs 29
444125 AI124882 Hs 118121 ESTs 29
453901 BE065902 gb RC2 BT0318 150200 011-b09 BT0318 Homo 29
421847 NM 014717 Hs 108884 KIAA0390 gene product 28
434424 AI811202 Hs 325335 Homo sapienε cDNA FLJ23523 fiε, clone L 28
422225 BE245652 Hs 118281 zinc finger protein 266 28
403011 28
405170 28
435878 R08330 Hs 20152 ESTε 28
436194 AK001074 Hs 333435 Homo sapiens cDNA FLJ10212 fis, clone HE 28
400394 AF040257 Hs 283818 Homo sapiens TNF receptor homolog mRNA, 28
411244 AW833768 gb QV4-TT0008 130100 077-e06 TT0008 Homo 28
441817 AW969706 Hε 293332 ESTs 28
456118 AA380267 Hε 78277 DKFZP434F2021 protein 28
417801 AA417383 Hs 82582 integπn, beta like 1 (with EGF-like rep 28
442717 R88362 Hs 180591 ESTs Weakly similar to T23976 hypotheti 28
402131 28
428959 AF100779 Hε 194680 WNT1 inducible signaling pathway protein 28
438160 AA779332 Hs 122671 ESTs 28
407594 AW057584 Hs 160681 ESTs 28
417877 AI025829 Hs 86320 ESTs 28
439235 N45513 Hs 46608 ESTs 28
451257 AA016255 Hs 31856 ESTs, Weakly similar to K1AA1453 protein 28
437113 AA744693 gb ny26c10 s1 NCI.CGAP.GCB1 Homo sapienε 28
430882 BE174240 Hs 79024 heterogeneous nuclear πbonucleoprolein 28
409978 D31897 Hs 57714 double C2-lιke domains, alpha 28
410672 AW794600 gb RC6-UM0014-170300-022-C05 UM0014 Homo 28
412236 AW902583 gb QV3-NN1024-260400-171410 NN1024 Homo 28
417827 T79366 Hs 108258 aotin binding protein, macrophin (microf 28
420206 M91463 Hs 95958 solute camerfamily 2 (facilitated glu 28
449676 AW380579 Hs 209657 ESTs 28
454778 AW820199 gb QV2-ST0296-190100 029 a07 ST0296 Homo 28
451203 AW070604 Hs 46517 ESTs 28
450180 AW449644 Hs 257182 ESTs 28
409432 D49372 Hs 54460 small inducible cytokine subfamily A (Cy 28
442264 AI278777 Hs 263455 ESTε, Weakly similar to ALULHUMAN ALU S 28
450003 AA777809 Hs 191995 ESTε 28
401602 28
413986 Z43567 gb HSC1FC021 normalized infant brain cDN 28
436187 AK000998 Hs 297221 Homo εapienε cDNA FU10136 fiε, clone HE 28
415652 T79213 Hs 272073 ESTs 28
404076 28
409416 AW388359 Hs 10667 ESTs 28
420814 AA721156 Hs 190440 ESTs 28
426960 AA393713 gb zt71h04 r1 Soares.testis.NHT Homo εap 28
419227 BE537383 Hs 89739 choliπergic receptor, πicotinic, beta po 28
448597 BE613250 Hs 98265 KIAA1877 protein 28
409928 AL137163 Hε 57549 hypothetical protein dJ473B4 28
433077 AA314262 Hε 301917 YDD19 protein 28
436720 AW975902 gb EST388011 MAGE reεequences, MAGN Homo 28
447410 AI470235 Hs 172698 EST 28
414652 AI620599 Hs 72068 ESTs 28
430454 AW469011 Hs 105635 ESTs 28
412417 AA102268 Hs 158622 ESTs 28
423130 AW897586 Hs 21213 ESTs 28
430660 R11884 Hs 100826 ESTs 28
401098 28
454036 AA374756 Hs 93560 Homo sapiens mRNA for KIAA1771 protein, 28
403549 28
414394 AI904738 Hs 76053 DEAD/H (Asp Glu-Ala Asp/Hiε) box polypep 28
412323 AW937143 gb PM1-DT0041-281299 001 f01 DT0041 Homo 28
433513 AI566356 Hs 171437 ' ESTε 28
446677 AI800311 Hs 156291 ESTε 28
457756 AA126136 Hs 38125 interferon induced protein 75, 52kD 28
450895 N66727 Hs 10957 ESTs 28
434352 AF129505 Hs 86492 small muscle protein, X-linked 28 449358 AA001229 Hs 131436 ESTs 28
422816 AA323586 Hs 93235 ESTs 28
420756 AA411800 Hs 189900 ESTs 28
423532 BE090503 gb RC6 BT0717-110400 011-F11 BT0717 Homo 28
448870 BE181783 Hs 175358 ESTs, Weakly similar to A47582 B-cell gr 28
451206 H86228 Hs 271780 ESTs, Weakly similar to I38022 hypotheti 28
457314 AA479597 Hs 193669 hypothetical protein DKFZp586J1119 28
458023 AW978161 Hs 268555 5'-3' exoπbonuclease 2 28
422260 AA315993 Hs 105484 regenerating gene type IV 28
429638 AI916662 Hs 211577 kiπectiπ 1 (kineεm receptor) 28
408936 AL138043 Hs 293549 ESTε 28
411762 AW860972 gb QV0 CT0387-180300 167-h07 CT0387 Homo 28
416192 NM 005036 Hs 998 peroxisome proliferative activated recep 28
455310 AW893961 gb RC4-NN0027-060400 011-d11 NN0027 Homo 28
406992 S82472 gb beta -pol=DNA polymerase beta {exon a 27
421003 T72080 Hs 95667 F-box protein 30 27
429593 AK000332 Hs 209927 Homo sapiens cDNA FLJ20325 fis, clone HE 27
445611 AW418497 Hs 145583 ESTs 27
445747 AI820863 Hs 145328 ESTs, Weakly similar to ALU1 HUMAN ALU S 27
445017 AI205493 Hs 176860 ESTs 27
411726 AW858612 gb CM3 CT0341-190400 152 h12 CT0341 Homo 27
451917 AW391351 Hs 50820 Homo sapiens unknown mRNA 27
416805 F13271 Hs 79981 Human clone 23560 mRNA sequence 27
423020 AA383092 Hs 1608 replication protein A3 (14kD) 27
427134 AA398409 Hs 173561 EST 27
435689 AA694284 gb zι35c02 s1 Soares fetal liver spleen 27
429282 N27596 Hs 21342 ESTs 27
435731 AA699581 Hs 186811 ESTs 27
426682 AV660038 Hs 2056 UDP glycosyltransferase 1 family, polype 27
421274 BE160327 Hs 104572 ESTs 27
403776 27
409526 BE298751 Hs 55014 hypothetical protein FLJ10206 27
410201 AA126129 gb zm78c07 r1 Stratagene neuroepithelium 27
427839 AA608823 Hs 98244 ESTs 27
447884 H29505 gb ym60d10 r1 Soares infant brain 1NIB H 27
449396 BE169100 Hs 195029 ESTs 27
422988 AW673847 Hs 97321 ESTs 27
442772 AW503680 Hs 5957 Homo sapiens clone 24416 mRNA sequence 27
434890 AF161345 Hs 283930 Homo sapienε HSPC082 mRNA, partial eds 27
412400 AW948066 gb RCO MT0012-290300-031 -hi 0 MT0012 Homo 27
413998 AW103807 Hs 243933 ESTs 27
403677 27
423401 NM 001992 Hs 128087 coagulation factor II (thrombin) recepto 27
430698 AA492071 gb πe97b04 s1 NCI CGAP Kιd1 Homo sapiens 27
432591 AA643238 Hs 146144 ESTs 27
446800 AI341635 Hs 156486 ESTs 27
454938 AW846134 gb QV0-CT0179-091199-049-d02 CT0179 Homo 27
456869 BE467912 Hs 154294 discs, large (Drosophila) homolog 1 27
445233 AV653034 Hs 297559 ESTs 27
448756 AI739241 Hs 171480 ESTs 27
418379 AA218940 Hs 137516 fidgetin like 1 27
435068 H16262 Hs 31415 ESTs 27
406092 27
422036 AA302647 Hs 271891 ESTs, Weakly similar to ZN91 HUMAN ZINC 27
441541 AA938663 Hs 199828 ESTs 27
451395 AI082419 Hs 114761 ESTs 27
455880 BE153208 gb PM0 HT0335-050400-007-F10 HT0335 Homo 27
459275 AI808913 Hs 339352 Homo sapienε brother of CDO (BOC) mRNA, 27
423949 AI014546 Hs 130912 ESTε 27
435420 AI928513 Hs 59203 ESTs 27
439418 AI282149 Hs 56213 ESTs, Highly similar to FXD3 HUMAN FORKH 27
454790 AW820852 gb RC2-ST0301-120200-011412 ST0301 Homo 27
447453 AW608645 Hs 18800 hypothetical protein FLJ20281 27
454767 BE069199 gb QV3-BT0379-010300-105-g03 BT0379 Homo 27
413252 BE074910 gb RC5-BT0580470300-021-F12 BT0580 Homo 27
402429 27
403760 27
433128 AB021923 Hs 23367 EST-YD1 protein 27
435448 H17132 Hs 27085 ESTs 27
445706 AA305520 Hs 108812 hypothetical protein FU22004 27
422171 U50529 Hs 112434 Novel human gene mapping to chomosome 13 27
459023 AW968226 Hs 60798 ESTs 27
443246 T75157 Hs 337603 ESTs, Weakly similar to T08680 hypotheti 27
404569 27
410181 AI468210 Hs 261285 pleiotropic regulator 1 (PRL1, Arabidops 27
422897 AA679784 Hs 4290 ESTs 27
427038 NM 01463c I Hs 173288 i KIAA0155 gene product 27
449880 AI673006 Hs 23194S I ESTs 27
455992 BE179015 gb RC3-HT0612-080500-013-h 10 HT0612 Homo 27
415268 R53935 Hε 287827 ' ESTs, Highly similar to MDR3.HUMAN MULTI 27
446554 AA151730 Hs 301788 I nudix (nucleoside diphosphate linked oi 27
452512 AW363486 Hs 33763E i ESTs 27
440728 AW086077 Hs 153275 ! Homo sapienε cDNA FLJ22715 fis, clone H 27 419481 AI879195 Hs 90606 15 kDa selenoproteιn 27
454352 AW389668 gb RC2-ST0168 071299 013406 ST0168 Homo 27
422831 R02504 Hs 332943 ESTε 27
413646 BE155042 gb PMO HT0349 101299 002-E04 HT0349 Homo 27
426872 AA410446 Hs 112011 ESTε, Weakly similar to unknown [H sapie 27
459160 AI904723 gb CM BT066 120299 092 BT066 Homo sapien 27
421338 AA287443 gb zε52c10 r1 NCI CGAP.GCB1 Homo sapiens 27
446002 AI346468 Hs 145789 ESTs 27
454716 AW850684 gb IL3 CT0219 160200 063 D12 CT0219 Homo 27
406664 L34041 Hs 9739 glycerol 3-phosphate dehydrogenase 1 (so 27
453128 AW026516 Hs 31791 acylphosphatase 2, muscle type 27
408691 AW250525 gb 28216265pπme NIH MGC.7 Homo sapiens 27
454754 AW819191 gb CM1-ST0283 071299 061-dOB ST0283 Homo 27
439451 AF086270 Hs 278554 heterochromatin like protein 1 27
445225 AI216555 Hs 202398 ESTs 27
427175 H06924 Hs 23782 hypothetical protein FLJ 12847 27
411816 AW864609 gb PM3-SN0017-240300 001-h03 SN0017 Homo 27
438135 AI253025 Hs 190426 ESTs 27
405981 27
406005 27
430762 A1343652 Hs 105667 ESTs 27
438361 AA805666 Hs 146217 Homo sapiens cDNA FLJ23077 fis, clone L 27
412105 H07971 Hs 94319 VPS10 domain receptor protein 27
434684 AA737282 Hs 190911 ESTs 27
445660 AI702668 Hs 201955 ESTs 27
400844 26
415725 BE219771 Hs 237146 hypothetical protein FLJ12752 26
420159 AI572490 Hs 99785 Homo sapiens cDNA FLJ21245 fis, clone C 26
408812 BE397160 Hs 254763 ESTs, Weakly similar to A42442 integnn 26
430052 AF102850 Hs 227933 Alg5, S cerevisiae, homolog of 26
440310 AA878939 Hs 125406 ESTs 26
425659 AK000590 Hs 158836 hypothetical protein FLJ20583 26
417252 AA195014 Hs 85971 ESTs 26
427167 AI239607 Hs 99196 hypothetical protein MGC11324 26
431613 AA018515 Hs 264482 Homo sapiens mRNA, cDNA DKFZp761 A0411 (f 26
414546 BE379492 gb 601236215F1 NIH.MGC.44 Homo sapiens c 26
407494 U10072 gb Human forkhead family (AFX1) mRNA, pa 26
429643 AA455889 Hs 167279 FYVE-finger-contamiπg Rab5 effector pro 26
442240 AI791883 Hs 292719 ESTs 26
452821 AW471181 Hε 160874 ESTs 26
410238 N94320 Hs 144225 ESTs 26
419236 AA330447 Hs 135159 Homo sapiens cDNA FLJ11481 fis, clone HE 26
440801 AA906366 Hs 190535 ESTs 26
440274 R24595 Hs 7122 scrapie responsive protein 1 26
411597 AW852925 gb PMO CT0248 131099 001410 CT0248 Homo 26
417956 AA210704 Hs 190465 ESTs 26
420621 AA278808 gb zs79c09 r1 NCI.CGAP.GCB1 Homo sapiens 26
425176 AW015644 Hs 155005 TEA domain family member 1 (SV40 transcr 26
425492 AL021918 Hs 158174 zinc finger protein 184 (Kruppel like) 26
425698 NM 016112 Hs 159241 polycystic kidney disease 2-lιke 1 26
426098 NM 014906 Hs 166351 KIAA1072 protein 26
435113 AA665469 Hs 117136 ESTs 26
438188 AA779975 Hs 128859 ESTs 26
445550 AI242754 Hs 137306 ESTs 26
458804 AL157625 gb DKFZp761L2016_r1 761 (synonym hamy2) 26
448299 AA497044 Hs 20887 hypothetical protein FLJ 10392 26
436407 T88803 Hs 271507 ESTs, Weakly similar to TIM.HUMAN PROBAB 26
425195 AA352026 Hs 94319 VPS10 domain receptor protein 26
418282 AA215535 Hs 98133 ESTs 26
442757 AI739528 Hs 28345 ESTs 26
413470 N20934 gb yx54c11 s1 Soares melanocyte 2NbHM Ho 26
428527 AI902398 Hs 34492 Cyt19 protein 26
441209 AA922939 Hs 135742 ESTs 26
458679 AW975460 Hs 143563 ESTs 26
442279 AW867006 Hs 159970 ESTε 26
407244 M10014 Hs 75431 fibπnogen, gamma polypeptide 26
411880 AW872477 gb hm30f03 x1 NCI_CGAP_Thy4 Homo sapiens 26
404845 26
411693 AW857271 gb CMO-CT0307-210100-158-g09 CT0307 Homo 26
438298 H23542 Hs 181788 ESTs 26
444517 AI939339 Hs 146883 ESTs 26
455870 AW452631 Hs 313803 ESTs, Highly similar to AF157833 1 noncl 26
457630 AI680803 Hs 112627 ESTs 26
424015 N95696 Hs 166361 Homo sapiens mRNA, cDNA DKFZp564F112 (fr 26
417563 AA203701 gb zx52a10 r1 Soares fetal liver.spleen. 26
413174 AA723564 Hs 191343 ESTs 26
438875 AA827640 Hs 189059 ESTs 26
440700 AW952281 Hs 296184 guanine nucleotide binding protein (G pr 26
423257 AW161039 Hs 125878 l synapεin III 26
431086 AI829692 Hs 211561 ESTs 26
409337 H71289 Hs 220535 i ESTs 26
442818 AK001741 Hε 8739 hypothetical protein FLJ10879 26
410004 AI298027 Hs 5057 carboxypeptidase D 26 455935 BE158687 gb CMO HT0395-280100 169 b09 HT0395 Homo 26
403273 26
445955 AA332209 Hs 158196 transcπptional adaptor 3 (ADA3, yeast h 26
425626 A1537536 Hs 173519 ESTs 26
451531 AA018311 Hs 114762 ESTs 26
428085 AA421081 Hs 12388 ESTs 26
429761 AI276780 Hs 135173 ESTs 26
437958 BE139550 Hs 121668 ESTs Moderately similar to PC4259 fern 26
442666 W74633 Hs 303720 ESTs 26
413088 BE064962 gb RC1 BT0313 130400016 c02 BT0313 Homo 26
419107 AW085152 Hs 292987 ESTs 26
435766 R11673 Hs 186498 ESTs 26
452879 AW905328 Hs 180842 nbosomal protein L13 26
440400 AA994364 Hs 125594 ESTs Weakly similar to T25472 hypotheti 26
440460 H92571 Hs 234478 Homo sapiens cDNA FLJ22648 fis, clone H 26
424146 AA705092 Hs 202368 ESTs 26
439950 AW937417 Hs 293561 ESTs 26
410366 AI267589 Hs 302689 hypothetical protein 26
417485 AA203304 Hs 32826 CG1 130 protein 26
412566 AW962574 gb EST374647 MAGE resequences MAGG Homo 26
416498 U33632 Hs 79351 potassium channel subfamily K member 1 26
440397 AA884448 Hs 157239 ESTs 26
451236 AI767406 Hs 207026 ESTs Weakly similar to B56205 transcπp 26
411819 AW947884 gb PM1-MT0010-200300 001 g08 MT0010 Homo 26
430357 AW976789 Hs 165607 ESTs 26
432869 AW974094 gb EST386197 MAGE resequences, MAGM Homo 26
427506 AK000134 Hs 179100 hypothetical protein FLJ20127 26
401614 26
404531 Z25884 Hs 121483 chloride channel 1 , skeletal muscle (Th 26
426698 AA394104 Hs 97489 ESTs 26
440479 AA886461 Hs 208161 ESTs 26
443160 AI467915 Hs 36053 ESTs 26
419323 AI092379 Hs 135275 ESTs 25
442813 AI018435 Hs 270970 ESTs 25
436196 AK001084 Hs 333498 Homo sapiens cDNA FLJ10222 fis clone HE 25
433561 BE540937 Hs 20104 hypothetical protein FLJ00052 25
434059 AA649162 Hs 236456 ESTs 25
454836 AW833711 gb QV4-TT0008 251199-043-e11 TT0008 Homo 25
458589 AV654623 Hs 288141 hypothetical protein MGC3156 25
459716 25
436340 R42246 Hs 21606 ESTs 25
428020 L19058 Hs 181581 gluta ate receptor, lonotropic, kainate 25
416951 AA190926 Hs 190785 ESTs, Moderately similar to S65657 alpha 25
401078 25
410644 AW902125 gb QVO-NN1022-120500 220-h12 NN1022 Homo 25
411660 AW855718 gb RC1-CT0279 070100 021-a06 CT0279 Homo 25
425201 AA352111 gb EST60061 Activated T-cells XX Homo sa 25
455252 AW876627 gb RC3-PT0028-120200-013-d11 PT0028 Homo 25
439096 AA830185 Hs 269680 ESTε 25
442627 AI027990 Hs 132303 ESTs 25
457799 AF220188 Hs 236510 uncharacteπzed hypothalamus protein HTM 25
428799 AI478619 Hs 104677 ESTε 25
450402 BE218027 Hs 89969 ESTs 25
411156 AW819939 Hs 273629 ESTs 25
431673 AW971302 Hs 293233 ESTs 25
415706 BE182587 Hs 57485 ESTs 25
412882 BE006919 Hs 134106 ESTs 25
441300 R35063 Hs 181536 ESTs 25
413257 BE075035 gb PM3 BT0584-260300-002-g05 BT0584 Homo 25
434662 AA641957 gb πs18d08 r1 NCI CGAP.GCB1 Homo sapienε 25
455255 AW877139 gb QV2-PT0010-160400-133-g01 PT0010 Homo 25
417137 U46265 Hε 81281 mitochondnal πboεomal protein S21 25
417909 R35614 gb yg66e08 r1 Soares infant brain 1NIB H 25
458043 AW979009 Hε 326108 ESTs 25
417006 AW673606 Hε 80758 aspartyl-tRNA synthetase 25
442006 AW975183 Hs 292663 ESTs, Weakly similar to S72482 hypotheti 25
455756 BE079307 gb RC1-BT0623-120200-011-g09 BT0623 Homo 25
454032 W31790 Hs 194293 ESTs, Weakly similar to I54374 gene NF2 25
444963 AI916973 Hs 213603 ESTε 25
443526 AW792804 Hs 134002 ESTε 25
454532 AA344685 Hs 58831 regulator of Fas induced apoptosis 25
428832 AA578229 Hs 324239 ESTs, Moderately similar to ZN91.HUMAN Z 25
442003 AW297497 Hs 201891 ESTs 25
452768 AW069459 Hs 61539 ESTs 25
411355 AW838479 Hs 22692 ESTs 25
458890 AW865523 gb PM4-SN0020 010400 009 b05 SN0020 Homo 25
400074 25
405241 25
413096 BE065209 gb RC1-BT0314-310300 015-M2 BT0314 Homo 25
414349 BE512968 gb 601172296F1 NIH MGC.15 Homo sapiens c 25
422884 AW860975 Hs 13256 ESTε 25
429515 AL031228 Hs 204370 DNA segment on chromosome 6 (unique pse 25
431925 AK000890 gb Homo sapiens cDNA FU10028 fis, clone 25 442653 BE269247 gb 601185486F1 NIH.MGC.8 Homo sapiens cD 25
401882 25
458257 U48351 Hs 201219 ESTs Weakly similarto S18946 ultra hig 25
405336 25
439492 AF086310 Hs 103159 ESTs 25
459390 BE385725 gb 601276347F1 NIH_MGC_20 Homo sapiens c 25
436359 Z83806 gb H sapienε mRNA for axonemal dynein he 25
429322 Hs 199243 KIAA0231 protein 25
431699 NM.001173 Hs 267831 Rho GTPase activating protein 5 25
437107 AA745598 Hs 291840 ESTs Weakly similar to I78885 seππe/th 25
441953 H11695 Hs 322901 disrupter of silencing 10 25
442777 AW341541 Hs 271153 ESTs 25
453361 AA035197 Hs 107375 ESTs 25
455275 AW977806 gb EST389810 MAGE resequences, MAGO Homo 25
457824 R84938 gb yt65f04 r1 Soares retina N2b4HR Homo 25
428550 AW297880 Hs 98661 ESTs 25
445900 AF070526 Hs 13429 Homo sapienε clone 24787 mRNA sequence 25
456359 AI967991 Hs 93574 homeo box D3 25
414366 BE549143 gb 601076456F1 NIH_MGC_12 Homo sapiens c 25
452528 AA742457 Hs 291479 ESTs 25
408444 AW661839 Hs 253204 ESTs 25
440327 R12581 Hs 191146 ESTs 25
410406 AI969703 Hs 1466 glycerol kinase 25
457021 AW968934 Hs 173108 Homo sapienε cDNA FLJ21897 fis clone H 25
418948 AI217097 gb qd43h07 x1 Soares_fetal_heart_NbHH19W 25
435427 AA682573 Hs 188982 ESTs Weakly similar to organic anion tr 25
427791 AA412446 Hs 98138 ESTε 25
403509 AF231919 Hs 18759 KIAA0539 gene product 25
436590 AI393115 Hs 127655 ESTs 25
455556 AW995423 gb QV0-BN0042 010400 183 g08 BN0042 Homo 25
405869 25
408274 R17315 gb yg12g11 r1 Soares infant brain 1NIB H 25
448015 AI458065 Hs 23196 ESTs 25
454190 AW177821 gb IL3-HT0059 180899 007-C05 HT0059 Homo 25
436154 AA764950 Hs 119898 ESTs 25
406377 25
437030 AA742577 Hs 303781 EST 25
420815 AA280684 Hs 270584 ESTs 25
418421 R58620 Hs 85050 phospholamban 25
423638 AI003521 Hs 130310 Homo sapienε mRNA for cyclin B3 isoform 25
415425 F08365 gb HSCZSA121 normalized infant brain cDN 25
404577 25
403568 25
425967 NM.007159 Hs 4007 Sarcolemmal associated protein 25
449899 AI610700 Hs 103280 ESTs 25
451078 AI927694 Hs 204470 ESTs 25
453343 AA905353 Hs 121622 ESTs 25
428728 NM_016625 Hs 191381 hypothetical protein 25
409642 AW450809 Hs 257347 ESTs 25
426235 AI631964 Hs 34447 ESTs 25
452043 H86231 gb yt03f02 r1 Soares retina N2b5HR Homo 25
401992 25
419910 AA662913 Hs 190173 ESTs, Weakly similar to A46010 X linked 25
411036 AA857218 Hs 297007 membrane bound transcnption factor prot 25
444575 A1264847 Hs 22545 Homo sapiens cDNA FU 12935 fis, clone NT 25
449311 AI657014 gb tt49a12 x1 NCLCGAP GC6 Homo sapienε 25
454566 AW807605 gb MR4-ST0098-120100-001 b06 ST0098 Homo 25
454597 AW809648 gb MR4-ST0124-261099 015-d01 ST0124 Homo 25
413875 BE176776 gb RC3-HT0586-110300-011-g09 HT0586 Homo 24
421583 AA293333 gb zt53c09 r1 Soares ovary tumor NbHOT H 24
426237 AK001104 Hs 168241 hypothetical protein FLJ10242 24
454437 AI248173 Hs 191460 hypothetical protein MGC12936 24
419187 AA234852 Hs 44693 ESTs 24
444493 R59410 Hs 282094 ESTs, Moderately similar to I38022 hypot 24
405547 24
454086 AW885909 Hs 6975 PR01073 protein 24
417508 BE163512 Hε 180877 H3 histone family 3B (H33B) 24
416277 W78765 Hs 180145 HSPC030 protein 24
420976 AI924940 Hs 108082 ESTs, Weakly εimilar to T31636 hypotheti 24
406468 24
408617 R61736 Hs 124128 ESTs 24
418994 AA296520 Hs 89546 selectm E (endothelial adhesion molecul 24
445432 AV653771 gb AV653771 GLC Homo sapienε cDNA clone 24
454137 AW500340 Hs 313876 ESTs Weakly similar to I38022 hypotheti 24
455328 AW896438 gb PM1 NN0047 040400 001-d09 NN0047 Homo 24
409500 U08098 Hs 54576 sulfotransferase, estrogen preferring 24
434138 AA625804 gb zu86h01 s1 Soares_teεtιε_NHT Homo εap 24
419511 AA429750 Hε 75113 general transcription factor IMA 24
437980 R50393 Hs 278436 KIAA1474 protein 24
439999 AA115811 Hs 6838 ras homolog gene family, member E 24
403501 24
446845 AI343645 Hs 156108 ESTs 24
401775 24 410845 AW807182 gb MR4-ST0062-180200-001-b04 ST0062 Homo 24
411836 AW901879 Hs 314453 ESTs 24
412879 BE092219 gb IL2-BT0734-240400-071-B04 BT0734 Homo 24
421083 AA283628 Hs 298016 ESTs, Weakly similar to I38022 hypotheti 24
423513 AF035960 Hs 129719 transglutaminase 5 24
428882 AA436915 Hs 131748 ESTs, Moderately similar to ALU7.HUMAN A 24
428945 AW192803 Hs 98974 ESTs, Weakly similar to S65824 reverse t 24
434627 AI221894 Hs 39311 ESTs 24
435256 AF193766 Hs 13872 cytokine-like protein C17 24
435079 AA664192 gb ac05b03 s1 Stratagene lung (937210) H 24
458239 BE439877 Hs 283389 ESTs 24
414093 BE544867 Hs 283077 centrosomal P4 1-assocιated protein, unc 24
441262 AI809130 Hs 176906 ESTs 24
402076 24
427962 AA946582 Hs 8700 deleted in liver cancer 1 24
400587 24
403053 R58624 Hs 2186 eukaryotic translation elongation factor 24
411203 AW872430 Hs 273743 ESTs 24
447849 AI538147 Hs 164277 ESTs 24
454201 AB023191 Hs 44131 KIAA0974 protein 24
424131 AA335714 Hs 199665 ESTs 24
425921 NMJ07231 Hs 162211 solute carrier family 6 (neurotransmitte 24
440385 AA884283 Hs 192136 ESTs 24
417976 BE565892 Hs 83077 interleukin 18 (interferoπ-gamma-inducin 24
447179 AW015633 Hs 157299 ESTs 24
412977 AA125910 Hε 191461 ESTs 24
436958 AA740322 Hs 293539 Homo sapiens mRNA for KIAA1758 protein, 24
401361 24
403891 24
408419 AW250092 Hs 305953 zinc linger protein 83 (HPF1) 24
417002 T79613 Hs 14613 ESTs 24
439446 A1927629 Hs 57873 ESTs 24
458570 AW971698 Hs 12627 TJ6 protein 24
458624 AI362790 Hs 278639 KIAA1684 protein, likely homolog of mous 24
459344 AW499533 Hs 257976 ESTs 24
413488 BE144017 gb MRO-HT0165491199-004-d09 HT0165 Homo 24
412114 AW893891 Hs 240833 ESTε, Weakly similar to 138022 hypotheti 24
423296 AW957193 Hs 3327 Homo sapiens cDNA FLJ22219 fis, clone H 24
419983 W55956 Hs 94030 Homo sapienε mRNA, cDNA DKFZp586E1624 (f 24
428268 AA424957 Hs 294132 ESTε 24
450947 AI745400 Hs 204662 ESTε 24
423073 BE252922 Hs 123119 MAD (motherε againεt decapentaplegic, Dr 24
438142 T90309 Hs 269651 ESTε 24
409239 AA740875 Hs 44307 ESTs, Moderately similar to I38022 hypot 24
424235 NM.003181 Hs 143507 T brachyury (mouse) homolog 24
429063 AW363845 Hs 122142 ESTs, Weakly similar to A46010 X-linked 24
433868 AA612960 Hs 337300 ESTs 24
401645 24
432149 AW614326 Hs 157022 ESTs, Weakly similar to T34549 probable 24
453393 AW956392 Hs 110376 ESTs 24
436054 AI076262 Hs 119813 ESTs 24
425433 AA357471 gb EST66274 LNCAP cells I Homo sapiens c 24
417712 AA205569 Hs 194193 ESTs, Moderately similar to ALU1 HUMAN A 24
420639 AI683116 Hs 25328 ESTs, Moderately similar to ALU7 HUMAN A 24
453369 BE551550 Hs 232630 ESTs 24
405017 24
405385 24
435633 AI248152 Hs 270047 ESTs 24
457128 AI932995 Hs 183475 Homo sapiens clone 25061 mRNA sequence 24
430535 AW968485 gb EST380561 MAGE resequences, MAGJ Homo 24
434544 C05875 Hs 91575 ESTs 24
449432 AW451361 Hs 196529 ESTs 24
455219 AW879403 gb PM0-OT0019-150300-002-d01 OT0019 Homo 24
458734 AI554946 Hs 158794 ESTs 24
442179 AA983842 Hs 333555 chromosome 2 open reading frame 2 24
444313 AI140494 Hs 197955 KIAA0704 protein 24
440448 AA885428 Hs 125646 ESTε 24
441498 AI379248 Hs 58742 ESTs 24
438205 AA780365 Hs 122161 ESTs 24
402615 24
425707 AF115402 Hs 11713 E74-lιke factor 5 (ets domain traπscπpt 24
422306 BE044325 Hs 227280 U6 εnRNA-associated Sm-like protein 24
413697 AA131315 Hs 47144 DKFZP586N0819 protein 24
421755 AW169454 Hs 207422 ESTs, Weakly similar to S71949 metallopr 24
449007 AI620433 Hs 193201 EST, Weakly similar to NIP2.HUMAN BCL2/A 24
449916 T60525 Hs 299221 pyruvate dehydrogenase kinase, isoenzyme 24
418857 D10216 Hs 89394 POU domain, class 1, transcnption facto 24
422486 BE514492 Hs 117487 gene near HD on 4p16 3 with homology to 24
458914 BE327696 Hs 280922 ESTs 24
435061 AI651474 Hs 163944 ESTs 24
416458 AA180511 gb zp53f03 r1 Stratageπe NT2 neuronal pr 24
453785 AI368236 Hs 283732 ESTs, Moderately similar to ALULHUMAN A 24
421515 Y11339 Hs 105352 GalNAc alpha-2, 6-sιalyltransferase I, I 24 403003 24
405347 24
406091 24
428402 AW237531 Hs 326876 Homo sapiens S0X6 mRNA, complete eds 24
438762 AW844412 Hs 65450 reticulon 4 24
455780 BE088828 gb CM2-BT0693-230300 129 g09 BT0693 Homo 24
457024 AA397546 Hs 119151 ESTs 24
404249 24
443921 AI091310 Hs 134848 ESTs 24
407055 X89211 gb H sapiens DNA for endogenous retrovir 24
417154 AI674701 Hs 21388 ESTs 24
419720 AA249131 Hs 337778 hypothetical protein FLJ11068 24
405230 24
405935 24
436998 AA745625 Hs 291414 ESTs, Weakly similar to ALU8.HUMAN ALU S 24
445748 U80766 Hs 13252 Human EST clone 22453 mariner transposon 24
419233 AA458873 Hs 178306 ESTs 23
414277 BE269910 gb 601186291F1 NIH_MGC_8 Homo sapiens cD 23
452092 BE245374 Hs 27842 hypothetical protein FLJ11210 23
453736 AL118674 Hs 34871 zinc finger homeobox 1B 23
410888 AW861207 gb RC1-CT0302-120200-013 d04 CT0302 Homo 23
434239 AF119910 Hs 283047 hypothetical protein PR02964 23
434098 AA625499 gb af69g08 r1 Soares.NhHMPu.S1 Homo sapi 23
414195 BE263293 Hs 89605 cholinergic receptor, nicotinic, alpha p 23
445688 AI248205 Hε 153244 ESTs 23
451656 BE327088 Hs 212752 ESTs 23
423956 W28203 Hs 136169 Homo sapiens clone 25215 mRNA sequence, 23
413445 BE141022 gb MRO-HT0067-201099-002-d 10 HT0067 Homo 23
436149 AI754308 Hs 159452 ESTs 2 3
405629 2 3
432702 AW973953 Hs 293744 ESTs 2 3
433377 AI752713 Hε 43845 ESTs 23
444711 AH 88739 Hs 148488 ESTs 23
445621 AI733818 Hs 145549 ESTs 23
456432 AW966931 Hs 179662 nucleoso e assembly protein 1-lιke 1 23
449236 AJ403126 Hs 26373 Homo sapienε cDNA FLJ23449 fiε, clone H 23
459024 AA020799 Hs 262869 plasminogen like 23
441037 AA913360 Hs 126468 ESTs 23
431577 T34523 Hs 302040 Homo sapiens DNA sequence from PAC 43401 23
438782 AA828380 Hs 126733 ESTs 23
412328 AW937445 gb QV3-DT0043 090200-080-c09 DT0043 Homo 23
410999 AW813004 gb RC3-ST0186-230300-019-h02 ST0186 Homo 23
429044 AI261490 Hs 145527 ESTs 23
431655 AW971119 gb EST383206 MAGE resequences, MAGL Homo 23
439642 W81441 Hs 153967 ESTs 23
441721 AI288259 Hs 127652 ESTs 23
443482 AW188093 Hs 250385 ESTs 23
403416 AI744626 Hs 151385 KIAA0564 protein 23
416443 N69469 Hs 194225 ESTs 23
419714 AA758751 Hs 98216 ESTs 23
415511 AI732617 Hs 182362 ESTs 23
412344 AW938384 Hs 264190 vxuolar protein sorting 35 (yeast homol 23
449264 AI637649 Hs 196105 ESTs 23
451664 AA889081 Hs 153952 5' nucleotidaεe (CD73) 23
441269 AW015206 Hs 178784 ESTε 23
402333 23
453649 Y07494 Hs 34114 ATPase, Na+/K+ transporting, alpha 2 (+) 23
430680 AW138724 Hs 168974 ESTs, Highly similar to ALU7_HUMAN ALU S 23
404367 23
403696 23
441622 AW450957 Hs 224864 ESTs 23
411004 AW813242 gb MR3-ST0191-020200-207-g10 ST0191 Homo 23
411093 BE067650 gb MR4-BT0358-090300-003-e01 BT0358 Homo 23
428548 AA430058 Hs.98649 EST 23
404059 \ 23
446861 AI696519 Hε 14427 Homo sapiens cDNA FLJ21800 fis, clone H 23
413640 BE158118 gb MR2-HT0378-240200-205-d09 HT0378 Homo 23
423554 M90516 Hε 1674 glutamιπe-fπιctoεe-6-phoεphate tranεamιn 23
435338 AA678071 Hs 194300 ESTε, Weakly similar to I38022 hypotheti 23
442710 AI015631 Hs 23210 ESTs 23
444206 AW301017 Hs 146492 ESTs 23
451250 AA491275 Hs 236940 hypothetical protein FLJ12542 23
454784 AW820626 gb RCO-ST0299-190100-012-e10 ST0299 Homo 23
458455 AV648310 Hs 213488 ESTs 23
458521 AI651039 Hs 148559 ESTs 2.3
407938 AA905097 Hs 85050 phospholamban 23
439546 AF088056 gb Homo εapieπs full length insert cDNA 23
441274 AW593781 Hε 131357 ESTs 23
454314 AW364844 gb QV3-DT0044-221299-045-C03 DT0044 Homo 23
409660 AW452065 Hε 258905 ESTs 23
428532 AF157326 Hs 184786 TBP-interacting protein 23
411384 AW842115 gb RCO CN0026-090200-031-e11 CN0026 Homo 23
453687 T55674 Hs 283108 hemoglobin, gamma G 23 410140 AL134435 Hs 22269 neurexiπ 3 23
422443 NM 014707 Hs 116753 histone deacetylase 7B 2 3
409071 AW316932 Hs 181982 ESTs 23
421253 AI188102 Hs 31028 ESTs 23
441398 AA932398 Hs 292036 ESTs, Weakly similar to B34087 hypotheti 23
448458 AW614367 Hs 171054 ESTs 23
457225 AW820035 Hs 278679 a disintegnn and metalloproteinase doma 23
443718 AI083580 Hs 221373 ESTs 23
445568 H00918 Hs 268744 KIAA1796 protein 23
400582 23
411262 AW834480 gb MR2-TT0014-151199 011-b07 TT0014 Homo 23
401145 23
407440 AF227135 gb Homo sapiens candidate taste receptor 23
455121 BE156459 gb QV0 HT0368 040100 082 f06 HT0368 Homo 23
459077 N20370 Hs 235883 ESTs 23
448117 H49129 Hs 172982 ESTs 23
453331 AI240665 Hs 8895 ESTs 23
443751 AI285839 Hs 153324 EST 23
402038 23
402176 23
456605 AI827786 Hs 259044 ESTs 23
432479 AL042844 Hs 275675 katanin p80 (WD40-coπtaιnιng) subunit B 23
402527 23
449272 AW137656 Hs 197645 ESTs 23
411024 BE062590 gb QV1-BT0260-281099-023-f05 BT0260 Homo 23
455608 BE011437 gb CM4-BN0220 080500-170403 BN0220 Homo 23
458818 AI523857 Hs 232257 ESTs 2.3
419875 AA853410 Hs 93557 proenkephalm 23
405521 2 3
436517 BE080932 Hs 135225 ESTs 23
456801 AW961886 Hs 138263 Homo sapiens clone 24528 mRNA sequence 23
430444 AW296421 Hs 121035 ESTs 23
456208 AW299698 Hs 334625 Homo εapiens cDNA FLJ14890 fis, clone PL 23
430388 AA356923 Hs 240770 nuclear cap binding protein subunit 2, 2 23
416509 N57713 Hs 260899 ESTs, Moderately similar to ZN91 HUMAN Z 23
419337 AW291112 Hs 209978 ESTs 23
419699 AA248998 Hs 173044 ESTs, Weakly similar to I38022 hypotheti 23
454456 AW850984 gb IL3-CT0220-150200068-H08 CT0220 Homo 23
454633 AW811380 gb IL3 ST0143-290999 019-D05 ST0143 Homo 23
457028 AW449838 Hs 97562 ESTs 23
458925 R15891 Hs 281587 Human (clone CTG A4) mRNA sequence 23
428336 AA503115 Hs 183752 microseminoprotein, beta- 23
430850 BE144152 gb MR0-HT0165 060200 006-e02 HT0165 Homo 23
408622 AA056060 Hs 202577 Homo sapienε cDNA FLJ12166 fis, clone MA 23
421227 R78581 Hs 266308 mosaic seπne protease 23
426902 AH 25334 Hs 97408 ESTs 23
430789 AA632577 Hs 310235 ESTs, Weakly similarto I78885 senne/th 23
447475 AI380797 Hs 158992 ESTs 23
452148 AF007143 Hs 28205 Homo εapiens clone 23738 mRNA sequence 23
430712 AW044647 Hs 196284 ESTs 23
458103 AW780192 Hs 267596 ESTs 23
420959 AA282119 Hs 88975 ESTs 23
444098 AV647969 Hs 109694 KIAA1451 protein 23
445641 AI245987 Hs 149442 ESTs 23
449276 AW241510 Hs 252713 ESTs 23
452294 AI871925 Hs 117895 ESTs, Moderately similar to A47582 B-cel 23
457653 AI820719 Hs 154662 DnaJ (Hsp40) homolog, subfamily A, membe 23
459497 AA825742 Hs 87517 ESTs 23
412852 BE004117 Hs 37415 ESTs, Weakly similar to ALU1 HUMAN ALU S 23
437539 AA974673 Hs 121419 ESTs 23
421813 BE048255 gb tz49b05 y1 NCI_CGAP_Brn52 Homo sapien 23
411994 R67298 Hs 109087 Homo sapiens cDNA FLJ22845 fis, clone K 23
443476 AW068594 Hs 133878 ESTs, Weakly similar to YCD1 HUMAN HYPOT 23
452463 R36452 Hs 300817 ESTs 23
404936 23
442833 AA328153 Hs 88201 ESTs, Weakly similar to A Cham A, Cryst 23
440836 AW370882 Hs 222080 ESTs 23
405120 23
400238 23
407809 AW082279 Hε 244106 ESTs 23
412303 AW936336 gb QV4-DT0021-281299 070-g11 DT0021 Homo 23
420478 AA521259 Hs 193796 ESTs 23
441417 AI733297 Hs 144474 ESTs 2 3
445117 AI208754 Hε 147369 ESTs 23
431162 AW971180 gb EST383268 MAGE resequences, MAGL Homo 22
437036 AI571514 Hs 133022 ESTs 22
455849 BE146866 gb QV4-HT0222-211099 014406 HT0222 Homo 22
447624 AI640326 Hs 62713 ESTs 22
439780 AL109688 gb Homo sapienε mRNA full length inεert 22
405706 22
447732 AI758398 Hs 161318 ESTs 22
440625 BE539853 Hs 22452 Homo sapiens mRNA for KIAA1737 protein, 22
404257 22 437722 AW292947 Hs 122872 I ESTs, Weakly similar to JU0033 hypotheti 22
449133 AI631655 Hs 197919 I ESTs 22
456555 AW592167 Hs 293299 I ESTε 22
408134 AK000184 Hs 42945 i acid εphingomyelinaεe-like phosphodieste 22
428192 AA424051 Hs 304742 I ESTs 22
435634 T82384 I gb yc14f05 rl Stratageπe lung (937210) H 22
438018 AK001160 Hs 5999 i hypothetical protein FLJ 10298 22
446096 AI276454 gb ql71a12 x1 Soares.NhHMPu.S1 Homo sapi 22
448106 AI800470 Hs 171941 i ESTs 22
450232 BE300815 Hs 201326 ESTs 22
436134 AK000618 Hs 123784 ESTs 22
448466 AI522109 Hs 171066 ESTs 22
420678 AW593288 Hs 3530 TLS-associated seπne-argmine protein 2 22
430692 X80240 gb H sapienε endogenouε retrovirus HERV- 22
446453 AV658469 Hs 188646 ESTε, Weakly similar to ALULHUMAN ALU S 22
423611 AB011163 Hs 129908 KIAA0591 protein 22
444050 AW138295 Hs 135024 ESTs 22
431532 AI537817 Hs 270311 ESTs, Weakly similar to ALULHUMAN ALU S 22
422669 H12402 Hs 119122 ribosomal protein L13a 22
403388 22
403780 22
419423 D26488 Hs 90315 KIAA0007 protein 22
424719 H90452 gb yv01c03 r1 Soares fetal liver spleen 22
431453 AW753917 gb RC0-CT0299-291199-031-F02 CT0299 Homo 22
442078 AW268583 Hs 262629 ESTs 22
452975 M85521 Hs 244482 Homo sapiens, clone IMAGE 3611719, mRNA, 22
426197 AA004410 Hs 100009 acyl-Coenzyme A oxidase 1, palmitoyl 22
427119 AW880562 Hs 114574 22
400486 22
448482 AW294078 Hε 171092 22
402621 22
408363 NM 003389 Hs 44396 coronin, actin-bmding protein, 2A 22
424584 H10692 Hs 13310 ESTs 22
445061 AI253094 Hs 145227 ESTs 22
431065 AA491286 Hs 128792 ESTs 22
411908 L27943 Hs 72924 cytidme deammase 22
441826 AW503603 Hs 129915 phosphotπesterase related 22
446901 AI347274 gb tc05d02 x1 NCI_CGAP_Co16 Homo sapiens 22
422677 AL046388 Hs 208206 hypothetical protein FLJ21162 22
455534 AW991925 gb Plv13-BN0011-130100-002-b07 BN0011 Homo 22
400163 22
418882 NM 004996 Hs 89433 ATP-binding cassette, sub-family C (CFTR 22
409206 AW364844 gb QV3-DT0044-221299-045-c03 DT0044 Homo 22
410556 R32158 gb yh67a07 s1 Soares placenta Nb2HP Homo 22
432584 AA928829 Hs 47099 hypothetical protein FLJ21212 22
439482 W70045 Hs 58089 ESTs 22
447877 AI435184 Hs 164252 ESTs 22
418297 R91254 gb yp94e12 s1 Soares fetal liver spleen 22
403534 22
410594 AW770778 Hs 281238 ESTs 22
414000 BE242814 Hs 323494 ESTs, Weakly similar to T27544 zinc resi 22
432762 NM 014099 Hs 278924 PR01768 protein 22
437606 AA761594 Hs 122440 ESTs 22
438550 AW976002 Hs 258402 ESTs 22
439626 N22415 Hs 189080 ESTs 22
444540 AI693927 Hs 265165 ESTs 22
450024 AA005129 gb zh90h08 r1 Soares.fetal.liver.spleen. 22
456481 AA258033 Hs 108110 DKFZP547E2110 protein 22
435138 BE314734 gb 601152976F1 NIH_MGC 19 Homo sapiens c 22
412887 BE007420 gb PM3-BN0142-200300-001-C04 BN0142 Homo 22
454204 AW816498 gb QV0-ST0236-171299-075-b02 ST0236 Homo 22
408253 AW807476 Hs 21051 Homo sapiens mRNA for FLJ00012 protein, 22
432887 AI926047 Hs 162859 ESTs 22
448063 AI459108 Hs 159818 ESTs 22
416171 H23896 Hs 125790 leucine-nch repeat-containing 2 22
433098 AW190593 Hs 151143 ESTs 22
409781 AW812266 Hs 15220 zinc finger protein 106 22
423441 R68649 Hs 278359 absent in melanoma 1 like 22
423646 H02364 gb yj35d06 r1 Soares plxenta Nb2HP Homo 22
436572 AA723274 Hs 279596 ESTε 22
447044 AF030107 Hε 17165 regulator of G-protein signalling 13 22
448828 AI580296 Hε 174782 ESTs, Weakly similar to KIAA1437 protein 22
444585 AW170015 Hε6594 ESTs 22
437334 AL353947 Hs 283780 hypothetical protein DKFZp761N1814 22
431917 D16181 Hs2868 peπpheral myelin protein 2 22
400843 22
455688 BE067238 gb PM1-BT0348-151299-001-a12 BT0348 Homo 22
449560 AA001767 Hs 17924 ESTs, Moderately similar to ALULHUMAN A 22
408940 M58583 Hs662 cerebellm 1 precursor 22
455201 AW947884 gb PM1-MT0010-200300-001-g08 MT0010 Homo 22
413617 BE155373 Hs 279518 amyloid beta (A4) precursor-like protein 22
459495 BE544158 gb 601076707F1 NIH.MGC.12 Homo sapiens c 22
433225 AW816515 Hs 173540 ATPase, Class V, type 10D 22 444547 AV650207 Hs 282437 ESTs, Weakly similar to I38022 hypotheti 22
417156 N49476 Hs 166563 replication factor C (activator 1) 1 (14 22
416761 H85422 Hs 108556 ESTs 22
408867 AA437199 Hs 656 cell division cycle 25C 22
406748 AW339106 Hs 217493 annexm A2 22
427443 AA402713 Hs 97872 ESTs 22
452843 AI796769 Hs 208320 ESTs 22
427473 AW274439 Hs 252709 ESTs 22
433919 AA746311 gb oa56d12 r1 NCI.CGAP.GCB1 Homo sapienε 22
431058 AW968865 gb EST380941 MAGE resequences, MAGJ Homo 22
428679 AA431765 gb zw80c03 s1 Soares testis NHT Homo sap 22
415250 F02614 Hs 27319 ESTs 22
440253 AI651329 Hs 160289 ESTs 22
434470 AA634818 Hε 298138 ESTs 22
418849 AW474547 Hs 53565 Homo sapiens PIG-M mRNA for mannosyltran 22
432463 AA548518 Hs 186733 ESTs 22
400861 22
407287 AI678812 gb tu59d08 x1 NCI_CGAP_Gas4 Homo sapiens 22
414817 AW902892 Hs 23782 hypothetical protein FLJ12847 22
416143 AI955650 Hs 79033 glutaminyl peptide cyclotransferase (glu 22
449808 AA694220 Hs 15403 ESTs, Moderately similar to ALU7.HUMAN A 22
412314 AA825247 Hs 250899 heat shock factor binding protein 1 22
442952 AI743261 Hs 131860 ESTs 22
425187 AW014486 Hs 22509 ESTs 22
408221 AA912183 Hs 47447 ESTs 22
411480 AW848022 gb IL3 CT0214-231299-053-A09 CT0214 Homo 22
459681 22
414784 NM 000344 Hs 288986 survival of motor neuron 1, telomeπc 22
442726 AW136066 Hs 19145 ESTs 22
450433 AW444538 Hs 231863 ESTs 22
437642 AL079309 gb Homo sapiens mRNA full length insert 22
406298 22
409723 AW885757 Hs 257862 ESTε 22
433266 AI863224 Hs 31476 Homo sapiens cDNA FLJ 13872 fis, clone TH 22
435090 BE217923 Hs 149595 ESTs 22
457187 AA443927 Hs 144360 EST 22
446534 AI307356 Hs 175225 ESTs 22
403764 22
442735 R91949 gb yq06h06 si Soares fetal liver spleen 22
455221 AW867751 gb MR0-SN0038-290300 001-a03 SN0038 Homo 22
405965 22
408420 NM 006915 Hs 44766 retimtis pigmentosa 2 (X-linked recesεi 22
441679 BE502267 Hs 65996 ESTs 22
432781 NM 014133 Hs 278940 PRO0618 protein 22
448470 AW026226 Hs 309479 ESTs 22
419637 W27493 gb 31h10 Human retina cDNA randomly prim 22
443180 R15875 Hs 258576 claudin 12 22
422213 AA306385 Hs 133160 ESTs 22
423119 AA322201 Hs 131976 ESTs 22
450192 AA263143 Hs 24596 RAD51-ιnteractιng protein 22
428042 AA419529 Hs 76391 yxoviruε (influenza) reεistance 1, homo 22
400734 22
430499 AW969408 Hs 231991 ESTs 22
451134 AA318315 Hs 25999 hypothetical protein FLJ22195 22 401694 22 423531 AW752782 Hs 129750 hypothetical protein FU 10546 22
424419 AK001563 Hs 146589 hypothetical protein FU 10701 22
431364 AW971382 Hs 294016 ESTs, Moderately similar to B34087 hypot 22
436640 AA724411 Hs 156065 ESTs 22
436802 N34486 Hs 170504 ESTs 22
443994 AI094805 Hs 135522 ESTs, Weakly similar to S38038 hypotheti 22
445908 R13580 Hs 13436 Homo sapiens clone 24425 mRNA sequence 22
446412 AW135313 Hs 150098 ESTs 22
448390 AL035414 Hs 21068 hypothetical protein 22
449939 T86420 Hε 272139 ESTs 22
412700 BE222433 Hs 201262 ESTs, Weakly similar to I38022 hypotheti 22
453125 AW779544 Hs 115497 hypothetical protein FU22655 22
422757 AI909935 Hs 65551 Homo sapienε, Similar to DNA segment, Ch 22
452864 AA033714 Hs 287629 hypothetical protein FLJ14260 22
452441 BE222078 Hs 113069 ESTs 22
402395 22
459659 22
428186 AW504300 Hs 295605 mannosidase, alpha, clasε 2A, member 2 22
438432 AW444990 Hs 258800 ESTs, Weakly similar to I38022 hypotheti 22
409446 A1561173 Hs 67688 ESTs 22
408764 BE087164 Hs 302415 ESTs 22
408908 BE296227 Hs 250822 seππe/threonine kinase 15 22
414275 AW970254 Hs889 Charot-Leyden crystal protein 22
436992 AA741074 Hs 120750 ESTs 22
439634 W79377 Hs 167 microtubule associated protein 2 22
444199 AI128931 Hs 260681 ESTs, Moderately similar to ALUF HUMAN ι 22
446009 AI989885 Hs 231926 ESTs 22
435510 BE143837 gb MR0-HT0164-151299 012-b08 HT0164 Homo 21 403691 21
458333 AI000792 Hs 108209 ESTs 21
454560 AW807281 gb MR4 ST0062 240300-003 g01 ST0062 Homo 21
439343 AF086161 Hs 114611 hypothetical protein FLJ11808 21
421498 AA292084 Hs 191575 ESTs Moderately similar to ALU2_HUMAN A 21
414428 BE296906 Hs 182625 VAMP (vesicle associated membrane protei 21
406941 X58140 (NONE) 21
445712 AI458246 Hs 167451 ESTε 21
451270 AW341392 Hε 235795 ESTε 21
451403 AA885569 Hs 40819 Homo sapiens cDNA FLJ14511 fis clone NT 21
437073 AI885608 Hε 94122 ESTs 21
434789 AW292515 Hs 194317 ESTs Weakly similar to T08680 hypotheti 21
430884 AF053748 Hs 248114 glial cell derived neurotrophic factor 21
445944 H06336 Hs 13480 Homo sapienε clone 24875 mRNA εequence 21
405233 21
446512 H30351 Hε 207982 ESTε 21
403188 21
404443 21
433645 AI821746 Hs 190258 ESTs Moderately similar to ALU6.HUMAN A 21
414456 H74314 gb yu56e10 r1 Soares fetal liver spleen 21
433479 AW511459 Hs 249972 ESTs 21
455482 AW948353 gb RCO MT0015 130400-031-d07 MT0015 Homo 21
446364 AB006624 Hs 14912 KIAA0286 protein 21
452004 AI827815 Hs 277359 ESTs 21
405059 21
425457 AW964212 gb EST376285 MAGE resequenceε MAGH Homo 21
403317 U02687 Hε 385 fmε related tyrosine kinase 3 21
413801 M62246 Hs 35406 ESTs Highly similar to unnamed protein 21
415871 R55995 Hs 283309 ESTs Moderately similar to ALULHUMAN A 21
432774 AA564946 Hs 156280 ESTs 21
436349 AI445255 Hs 115315 ESTs 21
445532 BE138944 Hs 146200 ESTs 21
456313 AA225741 gb nc17b10 s1 NCI_CGAP_Pr1 Homo sapiens 21
412818 NM_003337 Hs 811 ubiquitin conjugating enzyme E2B (RAD6 h 21
450271 AI693900 Hs 200920 ESTs 21
401521 21
422880 AF228704 Hs 121524 glutathione reductase 21
448871 BE616709 Hs 159265 kruppel related zinc finger protein hcKr 21
449233 BE048401 Hs 196511 ESTs 21
408217 AI433201 Hs 279860 tumor protein translationally-controlle 21
457003 S78234 Hε 172405 cell division cycle 27 21
417448 AA203135 Hs 130186 ESTs 21
402103 21
450579 AW136774 Hs 48614 ESTs 21
429597 NM_003816 Hs 2442 a disintegnn and metalloproteinase doma 21
456596 AA291834 Hε 78950 branched chain keto acid dehydrogenase E 21
415333 H24415 Hs 13273 KIAA0592 protein 21
457353 X65633 Hs 248144 melanocortin 2 receptor (adrenocorticotr 21
434985 AA658229 Hs 291228 ESTs 21
414729 BE466928 Hs 281901 ESTs 21
400510 21
420844 AA595522 gb nh22c09 s1 NCI_CGAP_Pr1 Homo εapiens 21
427434 BE538374 Hs 301732 hypothetical protein MGC5306 21
432188 AI362952 Hs 2928 solute earner family 7 (cationic ammo 21
446296 AA985662 Hs 63131 Homo εapιenε cDNA FU13155fis clone NT 21
453853 AL040600 Hs 188083 ESTs 21
459108 AW084176 Hs 223296 ESTs Weakly similar to I38022 hypotheti 21
430118 AI377255 Hs 183287 ESTs 21
455964 BE166924 gb CM4-HT0501 240300-519401 HT0501 Homo 21
437981 AA774445 Hs 192095 ESTs Weakly similar to KIAA1397 protein 21
439957 AI453184 Hs 66357 ESTs 21
423734 H02217 gb yj38d11 r1 Soares plxenta Nb2HP Homo 21
450721 AI732271 Hs 25567 ESTs 21
429392 AL109712 Hs 296506 Homo sapienε mRNA full length insert cDN 21
429986 AF092047 Hs 227277 sine oculis homeobox (Drosophila) homolo 21
432919 AL079800 gb DKFZp434O2330 r1 434 (synonym htes3) 21
434791 AA649235 Hs 116457 ESTs Weakly similar to NIP3.HUMAN BCL2/ 21
445273 AI218441 Hs 153846 ESTs 21
400514 21
412798 AW998657 Hs 119120 E3 Ubiquitin ligase SMURF1 21
416085 H18072 Hs 92576 ESTs 21
437846 AA773866 Hs 244569 esophagus cancer related gene 2 21
439391 AW975638 Hs 293490 ESTs Weakly similar to 138022 hypotheti 21
428414 AL049980 Hs 184216 DKFZP564C152 protein 21
429430 AI381837 Hs 155335 ESTs 21
449689 AF228421 Hs 23889 DKFZP564A032 protein 21
430909 AF034632 Hs 248126 G protein-coupled receptor 38 21
453116 AI276680 Hs 146086 ESTε 21
416312 W02640 Hs 16247 ESTs Weakly similar to 2004399A chromos 21
423019 AI640185 Hs 283626 ESTs 21
414007 AI733895 Hs 103813 ESTs 21
459535 AV654907 gb AV654907 GLC Homo sapiens cDNA clone 21
448776 BE302464 Hs 30057 MRS2 (S cerevisiae) like magnesium hom 21 421279 AW664878 Hs 106645 ESTs 21
443167 AI202009 Hs 132087 ESTs 21
459124 AW301478 Hs 184592 protein kinase, lysine deficient 1 21
448078 AI460117 Hs 170464 ESTε Highly similar to A53933 myosin I 21
436858 BE545498 gb 601070344F1 NIH.MGC.12 Homo sapienε c 21
430521 NM.016383 Hs 242183 HOM-TES 85 tumor antigen 21
431089 BE041395 Hs 283676 ESTs, Weakly similar to unknown protein 21
407401 AF029325 gb Homo sapiens laminin beta4 chain pre 21
426336 AA375802 gb EST88135 HSC172 cells II Homo sapiens 21
451124 AH 86203 Hs 31432 cardiac ankyπn repeat protein 21
425541 AA359119 gb EST68172 Fetal lung II Homo sapiens c 21
406504 21
410626 BE407727 gb601299771F1 NIH_MGC_21 Homo sapiens c 21
415186 AA160945 Hs 14479 Homo sapiens cDNA FLJ14199 fis, clone NT 21
416175 H24230 Hs 271498 ESTs, Moderately similar to ALU1 HUMAN A 21
436820 AI684535 Hs 200811 ESTs 21
442095 AI733162 Hs 128470 ESTε 21
451878 AI821027 Hs 8429 ESTs 21
449178 AI633748 Hs 197597 ESTs 21
427307 AF117947 Hs 174795 PDZ domain-containing guanine nucleotide 21
415857 AA866115 Hs 127797 Homo sapiens cDNA FLJ11381 fis, clone HE 21
425154 NM 001851 Hs 154850 collagen, type IX, alpha 1 21
449746 AI668594 Hs 176588 ESTs, Weakly similar to CP4Y HUMAN CYTOC 21
441543 AI733014 Hs 269715 ESTs 21
403065 21
428811 AA436052 Hs 99487 ESTs 21
451803 BE541174 Hs 252058 ESTs, Moderately similar to PC4259 fern 21
442906 AW296888 Hs 170939 ESTs 21
409171 R17126 gbyg09c11 r1 Soares infant brain 1NIBH 21
414175 AI308876 Hs 103849 hypothetical protein DKFZp761D112 21
450785 AA852713 Hs 25459 Homo sapiens, alpha-1 (VI) collagen 21
412039 AW887384 gb RCO OT0089-130300021 d07 OT0089 Homo 21
453055 AW291436 Hs 31917 Homo sapiens, clone MGC 9658, mRNA comp 21
443268 AI800271 Hs 129445 hypothetical protein FLJ12496 21
455022 AW850845 gb IL3 CT0220-111199-028 D11 CT0220 Homo 21
447972 AL137275 Hs 20137 hypothetical protein DKFZp434P0116 21
422942 AF054839 Hs 122540 tetraspaπ 2 21
400451 21
406668 T62745 Hs 184411 albumin 21
450159 AI702416 Hs 200771 ESTs, Moderately similar to A Chain A, T 21
404834 21
448732 BE614063 Hs 334689 KIAA1838 protein 21
423453 AW450737 Hs 128791 CGI-09 protein 21
421447 AB005216 Hs 104481 Nek, Ash and phospholipase C binding pro 21
408774 AW270899 Hs 254569 ESTs, Weakly similar to B34087 hypotheti 21
419986 AI345455 Hs 78915 GA-binding protein transcnption fxtor, 21
405732 21
417848 AA206581 Hs 39457 ESTs, Weakly similar to JC5314 CDC28/cdc 21
442875 BE623003 Hs 23625 Homo sapiens clone TCCCTA00142 mRNA sequ 21
420344 BE463721 Hs 97101 putative G protein-coupled receptor 21
455778 BE088746 gb CM2-BT0693-210300-123-d09 BT0693 Homo 21
426953 AI769281 Hs 97439 ESTs 21
440454 AI733037 Hs 129990 ESTs 21
433917 AI809325 Hs 122814 Human DNA sequence from clone RP5-1028D1 21
424872 AA347923 gb EST54302 Fetal heart II Homo sapienε 21
454658 AW812330 Hs 11123 DKFZP564G092 protein 21
441963 AI733307 Hs 128002 ESTε 21
439498 AA908731 Hs 58297 CLLL8 protein 21
456224 AW292905 Hs 128770 ESTε 21
413525 BE145899 gb MRO-HT0208-221299-2044)10 HTO208 Homo 21
444702 AI220122 Hs 326560 hypothetical protein MGC2780 21
417787 R14948 Hs 23883 ESTε 21
400612 21
410878 AW809201 Hs 314248 ESTε, Weakly similar to ALU4.HUMAN ALU S 21
414494 AA768491 Hs 6783 hypothetical protein FU22724 21
427027 AI924294 Hs 173259 uncharxteπzed bone aπow protein BM03 21
451067 BE172186 gb MRO-HT0559-110300-005-h11 HT0559 Homo 21
455032 AI830890 Hs 192422 ESTs 21
417945 R29072 gb F1-101 D 22 week old human fetal liver 21
438268 AA782163 Hs 293502 ESTs 21
424754 R09692 gb yf23b12 r1 Soareε fetal liver εpleeπ 21
404599 21
459655 21
402455 21
459278 AW294659 Hs 34054 Homo sapiens cDNA FU22488 fis, clone H 21
421987 AI133161 Hs 286131 CGI-101 protein 21
400339 X57131 Hs 248208 i H2A histone family, member F, pseudogene 21
438206 AA780385 Hs 187885 i ESTs 21
458451 AW297181 Hs 195925 I ESTs 21
447534 AW953935 Hs 30837 ESTs 21
417687 AI828596 Hs 250691 ESTs 21
412717 W00973 Hs 33472E I ESTs 21
405759 21 2 1
442081 AA401863 Hs 22380 ESTs 2 1
457938 AI373638 Hs 133900 ESTs 2 1
420687 AA279392 Hs 88605 Homo sapiens cDNA FLJ13427 fis, clone PL 2 1
428822 W28418 Hs 30715 potassium voltage gated channel, Isk-rel 2 1
415635 F13168 gb HSC3JF101 normalized infant brain cDN 2 1
411421 BE272110 Hs 21177 ESTs 2 1
437825 AA769123 Hs 291947 ESTs 2 1
437083 AW082597 Hs 244862 ESTs 2 1
409466 AA436207 Hs 226666 ESTs, Moderately similar to I54374 gene 2 1
433523 H29882 Hs 162614 ESTs 2 1
446868 AV660737 Hs 135100 ESTs 2 1
445882 AI948717 Hs 225155 ESTs, Weakly similar to A46302 PTB-assoc 2 1
438005 BE151746 gb PM1-HT0305-061299-003-a06 HT0305 Homo 2 1
406817 AI936028 gb wo47a09 x1 NCI_CGAP_Gas4 Homo sapiens 2 1
410486 AW235094 Hs 69233 zinc finger protein 2 1
411940 AW876686 gb CM4-PT0031-180200-507-e05 PT0031 Homo 2 1
412446 AI768015 Hs 92127 ESTs 2 1
457289 AW573204 Hs 137078 ESTs 21
400335 Y13187 Hs 248067 Homo sapiens dmd gene, intron 11 20
435959 AW296243 Hs 118375 ESTs 20
448188 AW001835 Hs 13323 hypothetical protein FLJ22059 20
418339 AA639902 Hs 104215 ESTs, Moderately similar to SPCN_HUMAN S 20
420430 AI703192 gb wd92h04 x1 NCI CGAP Lu24 Homo sapiens 20
445717 AW664658 Hs 149332 ESTs 20
451862 H09260 Hs 32333 ESTs 20
459686 20
441996 BE349537 Hs 38383 ESTs 20
412194 AW900282 Hs 115412 hypothetical protein FLJ13881 20
444229 AV648613 Hs 282397 ESTs 20
441635 AI908538 Hs 133000 ESTs, Weakly similar to S26689 hypotheti 20
421387 AF059566 Hs 103983 solute carrier family 5 (sodium iodide s 20
414373 AW162907 Hε 75969 proline-rich protein with nuclear target 20
428209 AA424197 Hs 98947 ESTε, Weakly similar to S33496 trypsin [ 20
443520 W90022 Hs 186809 ESTs, Highly similarto LCT2.HUMAN LEUKO 20
409248 AB033035 Hs 51965 KIAA1209 protein 20
444518 AI160278 Hs 146884 ESTs 20
422237 M13149 Hs 1498 histidme-nch glycoprotein 20
409316 U28251 Hs 53237 ESTε, Highly similar to Z169_HUMAN ZINC 20
402725 20
413783 AA314337 Hs 301547 πbosomal protein S7 20
423867 AA331886 gb EST35757 Embryo, 8 week I Homo sapien 20
425008 AW675764 Hs 1 4248 ESTs 20
427271 AW195922 Hs 188758 connexm 59 20
444102 AV647953 Hs 83077 interieukin 18 (interferon-gamma mducin 20
445829 AI452457 Hs 145526 ESTs 20
452366 AK000464 Hs 29276 hypothetical protein FLJ20457 20
457652 AF116656 Hs 273809 Homo sapiens PR01167 mRNA, complete eds 20
429540 M85776 gb EST02297 Fetal brain, Stratageπe (cat 20
459456 AA486036 Hs 190124 ESTs 20
409840 AW502122 gb UI-HF-BROp-ajr-c-08-O-UI r1 NIH MGC 5 20
441025 AA913880 Hs 176379 ESTs 20
457802 T78013 Hs 167279 FYVE-finger-contaimπg Rab5 effector pro 20
445627 AW818475 Hs 7363 ESTε 20
440299 AI871778 Hε 250112 ESTs 20
401236 H24185 Hs 92918 hypothetical protein 20
429996 N90822 Hs 48969 ESTs 20
455135 AW857989 gb PM2-CT0328-281299-003-e04 CT0328 Homo 20
411537 BE073250 gb MRO-BT0551-060300402-e05 BT0551 Homo 20
433449 AW772282 gb hn71b05 x1 NCI CGAP Kιd11 Homo sapien 20
454197 BE140966 gb MRO-HT0065-081199-002-b06 HT0065 Homo 20
445297 BE544163 Hs 87128 hypothetical protein FU23309 20
403977 20
458948 AI695359 Hs 280943 ESTs 20
418663 AK001100 Hs 41690 desmocollm 3 20
411479 AW848047 gb IL3-CT0214-291299-052-A12 CT0214 Homo 20
426536 AI949749 Hs 44441 ESTs 20
442765 BE567353 Hs 99480 ESTs 20
400859 20
405829 20
411863 BE075244 Hs 12420 ESTs 20
415258 AW752247 Hs 293853 ESTs 20
416093 R60685 Hs 268698 ESTs, Moderately similar to ALUC HUMAN I 20
416184 R48481 Hs 269177 ESTs, Weakly similar to ALU6 HUMAN ALU S 20
437733 AI792574 Hs 122876 ESTs 20
453118 AW195849 Hs 252757 ESTs 20
457039 H29990 Hs 101937 sine oculis homeobox (Drosophila) homolo 20
444292 AI139794 Hs 146569 ESTs 20
431360 NM 000427 Hs 251680 loπcππ 20
407644 D16815 Hs 37288 nuclear receptor subfamily 1, group D, m 20
412029 AW886238 gb RC5-OT0078-280300-022-F01 OT0078 Homo 20
438522 AA809431 Hs 258886 ESTs 20
422634 NM 016010 l Hs 118821 CGI-62 protein 20 418790 H95693 gb yt95d11 s1 Soares pineal gland N3HPG 20
442950 AI500417 Hs 46764 ESTs 20
457040 N77624 Hs 173717 phosphatidic acid phosphatase type 2B 20
436464 AI016176 Hs 269783 ESTs, Weakly similar to ALULHUMAN ALU S 20
402674 20
408733 AW264812 Hs 254290 ESTs 20
408767 AA057279 Hs 211928 ESTs 20
432801 NM 016260 Hs 278963 zinc finger DNA binding protein Helios 20
418205 L21715 Hs 83760 tropoπin I, εkeletal fast 20
404604 20
413627 BE182082 Hε 246973 ESTε 20
402341 20
438090 AA777534 Hε 191992 ESTε 20
421303 T06464 gb EST04353 Fetal brain, Stratagene (cat 20
411417 AW845481 gb MR1-CT0056-201199 008 b04 CT0056 Homo 20
401986 20
415318 T06544 gb EST04433 Fetal brain, Stratagene (cat 20
417756 Z43056 gb HSC12B021 normalized infant brain cDN 20
418301 AW976201 Hε 53913 hypothetical protein FLJ 10252 20
433755 AW085934 Hε 120868 ESTε 20
435413 AI267476 Hs 46669 ESTs 20
435648 H24347 Hs 27524 ESTs 20
447555 AI391662 Hs 160963 Homo sapiens, clone MGC 12318, mRNA, com 20
458175 AW296024 Hs 150434 ESTs 20
458433 AL135352 Hs 255883 ESTε, Weakly similar to I38022 hypotheti 20
446595 T57448 Hs 15467 hypothetical protein FLJ20725 20
447678 BE385257 Hs 336457 Homo εapieπs dopamine receptor interacti 20
448150 AI472167 Hs 302739 ESTs 20
453445 AL036532 Hs 91453 ESTs 20
444420 AI148157 Hs 146766 ESTs 20
431956 AK002032 Hs 272245 Homo sapiens cDNA FU 11170 fis clone PL 20
413758 BE162391 gb PM2-HT0451-090100 002404 HT0451 Homo 20
428231 U17989 Hs 183105 nuclear autoantigen 20
455873 BE152239 gb QV4-HT0316-091199 028412 HT0316 Homo 20
430970 AI018210 Hs 144083 ESTs 20
412277 BE277592 Hs 73799 guanine nucleotide binding protein (G pr 20
413025 AA805265 Hs 291646 ESTs 20
424083 AF055018 Hs 139137 Homo sapiens clone 24442 mRNA sequence 20
427654 AA410183 Hs 137475 ESTs 20
410483 BE163567 gb QV3-HT0460-230200-101-b08 HT0460 Homo 20
423942 AF209704 Hs 135723 glycolipid tranεfer protein 20
430340 AA476777 gb zw94g11 r1 Soareε_total_fetU8_Nb2HF8_ 20
425686 M73531 Hs 1937 retinal degeneration, slow (retinitis pi 20
425075 AA506324 Hs 1852 xid phosphatase, prostate 20
400285 20
405966 20
407407 AF050198 gb Homo sapiens putative mitochondnal s 20
411459 BE142707 gb MR0 HT0157-191199-002-g12 HT0157 Homo 20
415105 D60166 gb HUM089G11B Clontxh human fetal brain 20
434531 AA642007 Hs 116369 ESTs 20
447153 AA805202 Hs 315562 ESTs 20
447185 AW377092 Hs 99601 hypothetical protein FLJ 12553 20
455696 BE067870 gb RC0-BT0362-021299 031-b06 BT0362 Homo 20
456510 AK001652 Hs 99423 ATP-dependeπt RNA helicase 20
400617 AF151064 Hs 36069 hypothetical protein 20
418647 AA226198 gb πc26a07 s1 NCI_CGAP_Pr1 Homo εapiens 20
401785 20
433417 AA587773 Hε 8859 Homo sapiens Similar to RIKEN cDNA 5830 20
420777 AA280223 Hε 130865 ESTs 20
439509 AF086332 Hε 58314 ESTs 20
430203 L36140 Hε 235069 RxQ protein like (DNA helicase Q1-lιke) 20
450382 AA397658 Hε 60257 Homo sapiens cDNA FLJ13598 fis, clone PL 20
455540 BE080231 gb RC4-BT0629 120200-012411 BT0629 Homo 20
437620 AW976930 Hε 128760 ESTs 20
407528 X64990 gb H sapiens mRNA HTPCRX16 for olfxtory 20
402048 20
403623 20
411518 AW850246 gb IL3 CT0219-291099-021-E07 CT0219 Homo 20
417531 NM.003157 ' Hε 1087 seππe/threoniπe kinase 2 20
422600 BE143586 Hε 87 retinoblastoma-like 1 (p107) 20
423347 AI660412 Hε 234557 ' ESTs 20
424560 AA158727 Hs 15055! i protein predicted by clone 23733 20
433153 AA578512 gb nh22e11 ε1 NCI_CGAP_Pr1 Homo sapiens 20
433347 AF023130 gb Homo sapiens Ras GRF2 mRNA, partial c 20
435373 AW665538 Hs 117689 ESTs 20
442988 AI026130 Hε 131683 ESTs 20
447505 AL049266 Hs 18724 Homo sapiens mRNA cDNA DKFZp564F093 (fr 20
454423 AW603985 gb RC4-CN0048 140100 011-a04 CN0048 Homo 20 Table 31B
Pkey: Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion: Genbank acceεsion numbers
Pkey CATnumber Accession
407764 10148491 BE008347 BE008320 BE083307 BE083311 AW075968
408274 1049991 R17315 Z43964 AA053547
408681 10749331 AW250525 BE265117
409171 11048791 R17126 R38456H02771
409206 1108161 1 AW364844 AW364847 AW937534 AW937593 AW937659
409623 11440471 AW449185 AW449665 BE220971
409699 11490331 BE154650 BE154785 AW468343 BE154816 BE154667
409816 11553961 AW500954AW501111 AW501394
409840 1156071 1 AW502122AW502125 AW501663 AW501720
410201 1183651 AA126129 AA126033 AA082561
410483 12049951 BE163567 BE073689 BE073747 BE073780 BE073739 BE073748 BE163495 AW750178 BE163491 BE073763 BE073671
410500 12063231 R09442 AW846115 AW846108 AW751967 AW846083 AW846087 AW846090
410536 12073221 N39533 AW753094 AW753093
410556 12081571 R32158 AW754055 AW754054 AW754053 AW754045 AW857320
410615 12122031 AW772721 AW873372 H89212
410626 1212621 -1 BE407727
410644 12137951 AW902125 AW792853 AW837703 AW837710
410672 12148821 AW794600AW794730
410845 1223881.1 AW807182 AW807328 AW807063 AW807183 AW807192 AW807033 AW807061 AW807286 AW807097 AW807270 AW807372 AW807280
AW807283
410888 12259551 AW861207 AW809508
410901 1226077.1 AW810001 AW810092 AW810170 AW809884 AW809664 AW810353 AW810428 AW810209 AW810429 AW810154 AW810168 AW809786
AW810006 AW809672 AW809694 AW810552 AW810345 AW810432 AW809960
410934 12272401 AW811114 AW811095 AW811087 AW811124 AW811054AW811094 AW811157
410999 12288091 AW813004 AW812962 AW812961
411004 12289751 AW813242 BE146089 AW813195 AW813173 AW813206 BE145953 BE146212 AW813196 AW854582 AW813241 BE061582
411018 12291321 AW813428AW813444AW813367 AW813368 AW813429 AW813424
411024 12293101 BE062590 AW813565 BE147101
411093 12319701 BE067650 AW817053
411186 12350901 AW821257AW821267 AW821283
411244 12364072 AW833768 AW833631 AW833435 AW833533 AW833554 AW833543 AW833557
411262 12369981 AW834480 AW834531 AW834637 AW834618 AW834653 AW834487
411311 12385301 AW836491 AW836461 AW836673
411377 12422381 AW841462 BE156657 BE156668 BE092475
411382 12425941 BE067246 BE067241 BE067254 BE067249 AW841960
411384 12427021 AW842115 AW842111 AW842103
411417 12450751 AW845481 AW845474 AW850849
411459 12467241 BE142707 BE142852 BE142723 BE142905 AW847712 AW847792 AW847858 AW847852 AW847654 AW847608 BE142961
411479 1247077.1 AW848047AW848202AW848631 AW848142 AW848702AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069
AW848905 AW848214
411480 12470891 AW848022 AW848704 AW848168 AW848959 AW848476 AW848699 AW848700 AW848761
411518 12486921 AW850246 AW850251 AW850302
411537 12488991 BE073250 BE073378 BE073379 AW850533 AW850529
411597 12508431 AW852925AW852922
411656 12529731 AW855576 AW855650 AW855578 AW855577 AW855642 AW855619 AW855624 AW855621
411660 12530781 AW855718 AW855740 AW855748
411688 12540761 AW953440T08189 AW857085
411693 12542061 AW857271 AW857308 AW857296 AW857258
411726 1255048.1 AW858612 AW861964 AW858600 AW861945 AW858445 AW861901 AW858546 AW861921 AW858395 AW861968 AW858394 AW858401
AW858404AW858399
411738 1255755.1 AW859353 AW859365 AW859362 AW859356 AW859351 AW859354 AW859355 AW859361 AW859348 AW859364 AW859372 AW859352
AW859349 AW859367 AW859360 AW859374 AW859350
411745 12561601 AW867826 AW859896
411762 12569061 AW860972 AW862598 AW862599 AW860988 AW860983 AW860898 AW860925 AW860922 AW860986 AW860984 AW860989
411772 12573861 BE170301 AW861539 AW904851 BE154336 BE154090 BE154275
411816 1259632.1 AW864609 AW864592 AW864594
411819 12597481 AW947884 AW947918 AW947888 AW947883 AW947897 AW947910 AW947905 AW864751 AW947878
411880 12631101 AW872477 BE088101 T05990
411940 12662621 AW876686 AW876717 AW877215 AW876691 AW876722 AW877218 AW876694 AW876725
412029 12725971 AW886238 AW886229 AW886244 AW887891 AW886289 AW886146
412039 12734971 AW887384 AW887372 AW887461 AW887315
412147 12794111 AW895984 AW895982 AW895983 AW895918 AW895772 AW895843 AW895847 AW895653 AW895652 AW895648 AW896054 M85583
412209 12836101 AW901456 AW901450 AW901441
412236 12845011 AW902583 AW902585 AW902695 AW902568 AW902580 AW902692 AW902684 AW902595 AW902573 AW902681
412282 12876791 BE160188 AW935785 BE160401 BE160319 BE160313 BE160395
412303 12881301 AW936336 AW936339
412321 12886081 AW936913 AW936959 AW936918 AW936909
412323 1288770.1 AW937143 AW937150 AW937141 AW937151 AW937132 AW937160 AW937191 AW937174 AW937195 AW937173 AW937159 AW937139
AW937171 AW937142AW937145 AW937165 AW937163 AW937164AW937137AW937179 AW937156 AW937140 AW937135 AW937170
412329 12889431 AW937445 AW937457 AW937364 AW937374 AW937395
412400 1292900.1 AW948066 AW948106 AW948020 AW948047 AW948011 AW948033 AW948034 AW948041 AW948028 AW948048 AW948046 AW948056
AW948025 AW948053 AW948043 AW948032 AW948037 AW948050 AW948060 AW948059 AW948051 AW948027 AW948038 AW948052
AW948036 AW948031 AW948030 AW948035 AW948039 AW948026 AW948044 AW948049 AW948042 AW948054 AW948055 AW948013
AW948058 AW948045 AW948057 AW948029 AW948003 AW948016 AW948123 AW948008 AW948001 AW948022 AW948014 AW948023
AW948004 AW948000 AW948018 412474 1298691 AI791451 AI791288 BE019234 BE296601 AA111939
412566 13064691 AW962574 BE073261
412879 13342721 BE092219 BE092361 BE006789
412887 13347411 BE007420 BE007419 BE007421 BE007422
412999 13432201 BE046255 BE046611 BE046716 BE046732 BE046273
413071 1348162.1 BE064032 BE064039 BE064027 BE064040 BE064045 BE063868 BE063890
413087 13487201 BE064655 BE153953
413088 1348732.1 BE064962 BE064979 BE064853 BE064857 BE064856 BE064977 BE064960 BE064860 BE064815 BE064957 BE064804 BE064816 BE064850
BE064806 BE064796 BE064818 BE064975 BE064819 BE064810 BE064668 BE065059
413096 13490781 BE065209 BE065364 BE065110 BE065111
413101 13491541 BE065215 BE155544 BE155541 BE155540 BE155542 BE155543
413252 13558771 BE074910 BE074913 BE074911 BE074903 BE074892 BE074935
413257 13559631 BE075035 BE074999 BE075006 BE075005 BE075032 BE075008 BE075037
413445 1370833.1 BE141022 BE141513 BE141532 BE141488 BE141481 BE141526 BE141516 BE141471 BE141478 BE141476 BE141475 BE141021 BE141533
BE141464 BE141490 BE141472 BE141480
413470 13716001 N20934 BE141875 BE141877
413488 13732341 BE144017 BE185527 BE144023
413499 13739101 BE144884 H97942
413525 13746351 BE145899 BE145848 BE145849 BE145853 BE145927 BE145925
413581 13783351 BE150618 BE150616 BE150626
413640 13812861 BE158118 BE158034 BE154709 BE154825
413646 13814881 BE155042 BE155040 BE154987 BE155012
413758 1386900 -1 BE162391
413875 13967661 BE176776 H85072
413986 1407201 Z43567 H24159 AA134240
414277 14321221 BE269910 BE296510 BE295925 BE269325
414349 1437515 -1 BE512968
414366 14386361 BE549143 BE390613 BE277344
414456 14476551 H74314 BE299593
414539 14603201 BE379046 BE395459
414546 14607041 BE379492 BE391967
414605 1465790 -1 BE390440
414955 15098691 C15506 D80541 D80506
415105 15226741 D60166 D60893 D60101
415131 15236801 D61119 D81508 D81734
415236 15310801 R41400 H06659 Z38637 F02023 T16516
415318 15338591 T06544 Z44549 F05465 R61128
415425 15364081 F08365 Z43395 R54298
415549 15396921 F11942 T78047 R13266
415628 15407691 F13080 R34751 T75411
415635 15408531 F13168 R21289 T77628
416035 15672541 H42314 H43080 H45217 H15384
416154 15739651 Z46122 H23303 R56554 H23055 T80310 R13090 Z45524
416458 1595831 AA180511 AA649022AW974566
416548 1600181 1 H62953 N76608 N72413
416616 16041131 H68270 H68271 R07781
416972 1636681 BE019670 AA191284AA191255
417428 16795191 N87579 T93706
417490 1683971 AA203335 R11393
417563 1687491 AA203701 R86895
417669 1692157.1 T99898 T92080 T91447 R07806 R07779
417756 16971541 Z43056 R13398 T80474
417909 17076571 R35614 R24837 R52440
417945 17111261 R29072 R29717 R29699 R29709 R29751 R29609 R29060 R29718 R29057 R29591 R29683 R29575 R28913 R28910
418297 17363431 R91254 T97156 R58711
418647 177521 1 AA226198 AA226513 AA383773
418790 1790281 H95693 W02322 AA228140 H95692
418856 1796491 AA362858 AW863761 AA229428
418948 1808081 AI217097 AW886090 W38035 W38792 AA232835 AW936043
419637 1866391 W27493 AA248063 AA249685 AA429679
419936 189181 1 AI792788 BE142230 AA252019
420111 1907551 AA255652AA280911 AW967920 AA262684
420430 1935381 AI703192 AW901259 AA278523 AA262062
420621 1951131 AA278808 BE082076 BE081812 BE081581
420844 1969861 AA595522AA280981 BE464358
420854 197072.1 AW296927 AI684514 AI263168 AA281079
421065 1989361 AA329711 AA287436 AA283148
421303 2010391 T06464 C17931
421338 2013781 AA287443 AA419385 BE084078 AI478347
421583 2042201 AA293333 AI820910 AA293403
421813 2076541 BE048255 AA313083 AA298419
422977 223410.1 AA631498 AI017191 AA491211 AA761823 AA714555 AA768099 AA808286 AI934069 AA570223 AA574389 AA582438 AI745346 AW964510
AA319642 AW853758 H56414
423121 2251751 AW864848 AA322213 AA322209 AW961624
423532 229362.1 BE090503 BE090490 BE090483 BE090501 BE090500 BE090365 BE090505 BE090509 BE090499 BE090502 BE090504 BE090497 AA327285
423646 2305971 H02364AA329065 AW958111 AW961436
423734 2314791 H02217AA330235 AW955673
423841 232507.1 AW753967 AA370795 AA331630 AW962550
423867 232732.1 AA331886 AW962659 AW962655 T89841
423871 2327491 AA331906 AA332484
424719 2428891 H90452 AA345767 AW964302 H90399
424754 2433051 R09692 R09414 AA346353
424872 2445051 AA347923 AA347928 AW961769 425156 247338 1 AA351364 H19138 R12960
425201 247933 1 AA352111 AW962247 AA429695
425374 250946.1 A1904013 AI904015 AA356332
425433 251775 1 AA357471 AA360564 AW962961
425457 252038 1 AW964212 AA357832 AA357831
425541 252945 1 AA359119 AW963014 D79884
425798 256586 1 AA364002AI522307
426076 260504 1 AW962714 AA369277 AA369278
426336 265003 1 AA375802 AA375642 AW963815
426497 268121 1 AA379913 AA379981 AW963523
426750 271252 1 AA383950 AA383958 AW966432
426800 272088 1 AA385085AW966617T87798
426960 273843 1 AA393713 AA400726
428679 294049 1 AA431765 AA432015
428740 294655.1 AA433838 AA450385 AA683244
429106 299886 1 AA446612 AA456438 AA476655
429540 305828 1 M85776 AA454535 AA456208 H90189
429875 310034 1 A1091815 AA460162 AA460761
430175 314040 1 AA468724 AA468772 AA468643 AW969231
430340 316229.1 AA476777 T86049
430535 319643 1 AW968485 AW968670 AA480922 BE350425
430553 319868 1 AW392821 AW392809 AW843258 AW843049 AW603156 BE165656 AW821728
430692 32200 1 X80240 AI064750 AH33594
430698 322100 1 AA492071 AA484229 AW969850
430757 322947 1 AI458623 AA639708 AA485409 R22065 AA485570
430850 324651 1 BE144152 AA937952AA487799
431058 327401.1 AW968865AA491199 C17148
431071 327550 1 AA491379 H86020 AW969148
431162 328726.1 AW971180 AA551515 AA493610AW089533
431169 328799 1 AW971240 AA493843 AA493723
431453 333457 1 AW753917 BE152926 AA505333 BE155673
431655 336189 1 AW971119 AA574265 AA513268
431822 338082.1 AA516049 AW004922
431925 33905 1 AK000890 BE182413 AW890890AW844179 BE178834
432189 342819.1 AA527941 AI810608 A1620190 AA635266
432363 345469 1 AA534489 AW970240 AW970323
432779 354024.1 AW979241 AA565006 AA847102
432869 355475 1 AW974094 AA569074 AA602574
432919 356290 1 AL079800 AA570294 L25459
433153 359936 1 AA578512 AA595535 BE177533
433347 36388 1 AF023130 AF181250AA984703AA694303 AA351792
433449 366532 1 AW772282AA592974
433919 377243 1 AA746311 AA927492 AA617995
434098 38O006 AA625499 AA625269 AA625184
434138 380572 1 AA625804 AW418787 AW074833 AI675642 AI393368
434662 390415.1 AA641957 AW749897 AW749866 AW749887 AW749890
434671 390655 1 R34758AA642317
435079 399783 1 AA664192 H60250 T71388
435138 401159 1 BE314734 AA666393
435463 406582.1 AA682507 AW851124
435510 407286.1 BE143837 AW749652 AA683327
435634 409239 1 T82384 R05307AA693714
435689 409755 1 AA694284 H68267 H68264
436359 41847 1 Z83806 AJ132091 AJ132090
436720 425676.1 AW975902 AA729344 AI557342
436858 428095.1 BE545498 AA830720 AI873015 AA732679
437037 431828 1 T63804T63768AA742849
437113 433234 1 AA744693 AW750059
437642 43997 1 AL079309 AA281819
437963 44635 -1 BE396279
438005 447553.1 BE151746 BE336853 D63271 T94955 AA774994
438993 467651 1 AA828995 AA834879 AI926361
439037 46803 1 AF075084 H53157 H53054
439546 47360 1 AF088056 W76297 W72448
439780 47673 1 AL109688 R23665 R26578
442653 54812 1 BE269247 BE270032 BE270800 BE566840
442735 550247 1 R91949 AI016237 BE072329
443764 579650.1 F23283 AI084941 F35774
444063 590989 1 AI122614AW869134
444910 624951.1 AI201849 BE069007 AW946544
445432 63943 1 AV653771 BE089370
446096 661959 1 A1276454 AI633717 AI275116
446901 697809 1 AI347274 AW844024
447884 740749 1 H29505 R18575 Z43580 T48738 AI435454 BE004683
448477 76475 1 BE612572 AL040190 F08514
449311 804513 1 AI657014 AW594035 AI657036 AI638390
450024 82296 1 AA005129 AA679084 AA694399
451067 85759 1 BE172186 AA059279 AA020815 AA013437
452043 89532 1 H86231 AA021632 H38271
452542 921410 1 AW812256 AW812257AI906423 AI906422
453211 95527 T W84829 AA033900 AW573557
453530 97021 1 AW021633 AA036730 AI866854
453823 982526 1 AL137967 BE064160 BE064186 453901 986414.1 BE065902 AW749032 AW003637 454186 1049781.1 BE141030 BE141474 BE141467 BE141753 BE141024 BE141761 AW177583 AW177579 AW177582 AW177585 AW177587 AW807582 AW177581
BE141477 BE141520 BE141456 BE141492 BE141028 BE141775 BE141489 BE141751 AW177599 BE141750 AW177597 BE141512 BE141460
BE141749AW177598
454190 1048996 1 AW177821 AW177896 AW177867 454197 1050392.1 BE140966 BE140961 BE140967 BE141006 BE140985 BE140970 BE141669 BE141653 BE141664 BE141655 BE141661 BE141660 BE140969
BE141673 BE141650 BE141674 BE141550 BE141688 AW178241 BE140994 BE141666 BE140998 BE141008 BE140988 BE141011 BE140975
BE141667 BE141675 BE141657 BE141681 BE141656 BE141672 BE141680 AW178237 BE141012 BE140990 BE141658 BE141648 BE141013
BE141668 BE140973 BE141004 BE140963 BE140984 BE141009 AW178232 BE141007 BE141649 AW178293 BE140993 AW178233 BE141646
BE141005 BE141691 BE141000 BE141652 BE140965 BE141562 BE140960 BE140962 BE141001 BE140978 AW178229 AW178239 BE141671
AW178230 BE141547 AW178235 BE141663 BE141549 BE140996 BE141003 A 178236 BE141002 BE141556
454204 1050597.1 AW816498 AW808791 AW808515 AW808379 AW808532 AW808605 AW808977 AW808816 AW178676 AW178486 AW808514 AW178483
AW178485 AW809007 AW808524
454314 1108161 1 AW364844 AW364847 AW937534 AW937593 AW937659
454352 1129667 1 AW389668 AW389657 AW609198 AW389649
454423 1183079 1 AW603985 AW854350
454447 1204995 1 BE163567 BE073689 BE073747 BE073780 BE073739 BE073748 BE163495 AW750178 BE163491 BE073763 BE073671
454456 1207088 1 AW850984 AW752836 M86124
454482 1215087 1 BE147919 AW794884 BE147847
454560 1223940 1 AW807281 AW807092 AW807425 AW807330 AW807174 AW807171 AW807274 AW807278 AW807367
454564 1224407.1 AW807573 AW807566 AW807572
454566 1224432 1 AW807605 AW807690 AW807839 AW807752 AW807673 AW807667 AW807955 AW807760 AW807615 AW807898 AW807849 AW807821
AW807832 AW807842 AW807827 AW807822 AW807829 AW807830 AW807825 AW807603 AW807612 AW807908 AW807595 AW807617
AW807678 AW807687 AW807918 AW807921 AW807596 AW807602 AW807688 AW807609 AW807684 AW807770 AW807593 AW807754
AW807679 AW807957 AW807683 AW807763 AW807902 AW807840 AW807819 AW807836 AW807769 AW807685 AW807847 AW807674
AW807686 AW807670 AW807917 AW807677 AW807680 AW807900 AW807669 AW807952 AW807907 AW807846 AW807756 AW807835
AW807608 AW807753 AW807601 AW807956
454597 1226059.1 AW809648 AW809704 AW809643 AW809653 AW809709 AW809949 AW809939 AW810010 AW809705 AW809950 AW809822 AW809667
AW810093 AW810076 AW809673 AW810349 AW809895
454633 1227504 1 AW811380 AW811385
454716 1230503 1 AW850684AW850150
454747 1233006 1 AW818535 AW818588 AW818651
454754 1233580.1 AW819191 AW819252 AW819183 AW819175AW819177AW819186 AW819180 BE158470 AW819242AW819269 AW819244AW819190
AW819265AW819268AW819246 BE152602AW819249AW819251 AW819263AW819194
454767 1234028.1 BE069199 AW936012 AW877466 AW819782 AW935798 AW835546 AW936042 BE069121 AW835625 AW877536 AW935885 BE069202
AW820019 AW935937 BE160180 AW935946 BE069101 BE069125 AW877527 BE160316 BE160398 AW935794 AW835701 AW935784
454778 1234343 1 AW820199 AW820434 BE174743
454784 1234630 1 AW820626 AW820621 AW820608
454790 1234752 1 AW820852 AW820773 AW821088
454836 1236509 1 AW833711 AW833620 AW833699
454864 1237929 1 AW835775 AW845768 AW845764 AW845773 AW845757 AW845758 AW845780
454938 1245635.1 AW846134 AW846467 AW846468 AW846386 AW846461 AW846211 AW846179 AW846205 AW846320 AW846379 AW846367 AW846561
AW846556
454962 1246750 1 AW847645AW847791 AW854083 AW853945
455022 1249160 1 AW850845 BE144010 AW855164
455121 1254339 1 BE156459 BE156469 BE156468 AW857447
455135 1254729 1 AW857989 AW858016 AW861677 AW861689 AW861691 AW858056
455170 1256906 1 AW860972 AW862598 AW862599 AW860988 AW860983 AW860898 AW860925 AW860922 AW860986 AW860984 AW860989
455201 1259748 1 AW947884 AW947918 AW947888 AW947883 AW947897 AW947910 AW947905 AW864751 AW947878
455219 1261640 1 AW879403 AW867707
455221 1261678 1 AW867751 AW867770 AW867763
455236 1265662 1 AW875972 AW875983 AW875974 AW876000 AW875966 AW876050
455252 1266222 1 AW876627 AW876630 AW876631 AW876625
455255 1266482.1 AW877139 AW877135 AW877018 AW991835 AW877128 AW877108 AW877017 AW877107
455275 1272255 1 AW977806 AW887923 AW886321
455280 1272607.1 AW886156 AW887926 AW886324 AW886236 AW887906 AW886304
455310 1278158 1 "AW893961 AW893998 AW894034 AW894019
455328 1280063 1 AW896438 AW896534 AW896500 AW896540 AW896446
455464 1292643 1 AW983901 AW984485 AW947715
455482 1293183 1 AW948353 AW948351 AW948331 AW948303 AW948336 AW948305 AW948299 AW948346 AW948352
455488 129372.-1 AA102322
455511 1321229 1 BE144762 AW979091
455534 1322942 1 AW991925 AW991919
455540 1323701 1 BE080231 AW993284 AW993293 AW993O00
455556 1325658 1 AW995423 AW995373
455571 1331885 1 BE003714 BE003721 BE003720 BE003716
455587 1335046 1 BE007829 BE007815 BE007822 BE007996 BE007835 BE007837 BE007824 BE007836 BE007827
455608 1337389 1 BE011437 BE011402 BE011395 BE011428 BE011407 BE011421 BE011406
455675 1349659 1 BE065984 BE065942 BE065955 BE066085
455688 1350606 1 BE067238 BE067235 BE067240 BE067256 BE067263 BE067236 BE067260 BE067253 BE067248 BE067252
455696 1351077 1 BE067870 BE067866 BE165133 BE165334 BE165329 BE165332
455747 1355877 1 BE074910 BE074913 BE074911 BE074903 BE074892 BE074935
455756 1358603 1 BE079307 BE079309
455778 1364506 1 BE088746 BE088802 BE088755 BE088876 BE088947 BE088881 BE088952
455780 1364580 -1 BE088828
455849 1375441 1 BE146866 BE146865 BE146867
455851 1375451 1 BE146879 BE146914 BE146918
455866 1377119 1 BE149024 BE149056 BE152826 BE149025BE149057 BE152819 BE149030 BE149062 BE149023 BE149055
455873 1379498 1 BE152239 BE152242 BE152230
455880 1380022 1 BE153208 BE153146 BE152981
455935 1384144 1 BE158687 BE158688
455964 1389912.1 BE166924 BE166921 BE166925 BE166915BE166970 BE166968
455992 1398552.1 BE179015 BE178965 BE179010 BE179002 BE178961 BE179005 BE178964 BE179012 BE179011 BE178963 BE178997 455993 1398665 1 BE179085 BE179084 BE179086 BE179264
456186 1618618 1 W26642 H88394
456313 177240 1 AA225741 AI734056 AI820965 A1732153 AA259201 AA225731
456394 1843275 -2 W28506
456407 184986 1 AW968614AA243209 AA281411
456476 191761 1 AA256753 AW628680
457242 307984 1 AA457011 AI978850
457824 41515 6 1 R84938 AL047151 AA310309 AW063200 AI569528 AI307823 N49975
458804 75803 1 AL157625 N72696 BE622492
458890 812733 2 AW865523 AW865128 AW865467 AW865127 AW865466
459160 920051 1 AI904723 AI904725 AI904729 AI904722 AI904758 AI904736
459201 925883.1 AW391177W45021
TABLE 31 C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham 1 et al " refers to the publication entitled T human chromosome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400451 8113550 Minus 82189-82320
400462 9929659 Minus 197610-197785
400486 8569885 Plus 181108-181605
400510 9796540 Minus 139633-139910,140469-140979
400514 9796594 Minus 78844-79025,80850-80991 ,89754-89941 ,93750-93891
400579 9887603 Plus 21323-21526
400582 9887609 Plus 88642-88726,89716-89866
400587 9887626 Plus 25435-25588,25668-25747
400608 9887666 Minus 96756-97558
400612 9929646 Minus 151513-151662
400613 9864507 Plus 92278-92472
400641 8117693 Plus 4786-4992
400643 8117693 Plus 12818-13016
400706 7249204 Minus 78299-78686
400734 8118979 Plus 122853-123971
400816 8569993 Plus 161221-162078
400843 9188605 Plus 5863-5970,7653-7784,8892-9023,9673-9807,10634-10789,15254-15403,23827-23958
400844 9188605 Plus 24746-24872,25035-25204
400859 9757499 Minus 91888-92018,98131-98294,99474-99570
400861 9757506 Plus 163855-164016
400889 9958234 Minus 169782-170036
401078 3687273 Plus 105052-105171
401098 9965518 Minus 85632-86174
401132 8705350 Minus 85679-85795
401145 2547238 Plus 17599-17776
401189 9690246 Minus 90815-90929
401200 9743387 Minus 111586-111806,114791-114916,115419-115583,116351-116446,116847-116907,122853-123067,124982-125407
401344 9926411 Minus 82478-82602,86952-87110
401361 9958052 Plus 153093-154106
401365 9796180 Minus 119572-119672
401449 8574316 Minus 144928-145030
401497 7381770 Plus 92607-92813
401521 7705251 Plus 9127-9234
401526 7770561 Plus 91570-93177
401602 7689963 Plus 101096-101253
401614 7839924 Plus 17350-17735
401645 7657839 Minus 34986-35133
401694 3540172 Minus 64056-64168
401775 9966311 Minus 110228-110340
401785 7249190 Minus 165776-165996,166189-166314,166408-166569,167112-167268,167387-167469,168634-168942
401882 8139716 Plus 86466-87077
401887 7229981 Plus 93973-94120
401986 4406829 Minus 31137-31293
401992 4153858 Plus 31452-31649
402038 7684482 Minuε 100751-100885
402048 8072512 Plus 43936-44078
402076 8117410 Plus 128316-128627
402103 7249203 Plus 14453-15414
402131 7704961 Minus 33114-33209,33496-33678
402176 7543687 Minus 10-750
402230 9966312 Minus 29782-29932
402333 8844110 Minus 165693-165856
402341 7656696 Plus 22583-23699
402395 9929693 Minus 131016-131998
402429 9796372 Minus 57622-57793,59282-59402,59624-59827
402430 9796372 Minus 62382-62552
402455 9796753 Minus 139640-139779,140568-140660
402527 9800806 Plus 4722-4916,17858 18037,19964-20140,24423-24605,26699-26881 402615 9926801 Pluε 131390-132157
402621 9930950 Plus 130806-131036
402674 8077108 Minus 39290-39502
402725 8979991 Plus 107231-107383
402790 4835258 Minus 147744-147861
402867 5596716 Plus 52806-53106,53500-53818
402953 9408724 Minus 122603-122743
403003 5441423 Minus 79403-79560,79712-80021
403011 6693597 Minus 3468-3623
403065 8954197 Minus 71615-71773,73930-74144
403188 9838289 Minus 157618-157755
403271 7230852 Plus 134283-134485
403273 8018055 Plus 133809-134099
403281 8072630 Minus 7521-7728
403296 8096530 Minus 35913-36520
403310 8139936 Minus 183883-184026
403329 8516120 Plus 96450-96598
403341 8569175 Plus 30699-30910
403344 8569726 Plus 70823-70990
403356 8569930 Plus 92839-93036
403381 9438267 Minus 26009-26178
403388 9438331 Plus 112733-113001,114599-114735
403396 9438367 Minus 952-1160
403501 7534005 Minus 108903-110438
403513 7656757 Minus 155310-155436,158402-158535
403515 7656757 Minus 173358-179553
403534 8076917 Minus 46652-47332
403549 8081591 Minus 137150-137362
403568 8101145 Minus 85509-85658
403574 8101156 Plus 5542-6176
403619 8569810 Plus 62501-62653
403623 8569879 Minus 3519-5426
403625 8569879 Plus 6551-7111
403637 8671936 Minus 142647-142771,145531-145762
403667 6850483 Minus 1344-1442,1545-1697
403677 7331517 Minus 55008-55083,62860-63051
403691 7387384 Minus 88280-88463
403696 3135242 Minus 143467-143634
403743 7652003 Minus 136463-136646
403760 7712202 Minus 45910-46260,47563-47824
403764 7717105 Minus 118692-118853
403776 7770611 Minus 1414-1513,1624-1756
403780 8076989 Plus 93160-93409
403786 8083636 Minus 73028-73217
403891 7331467 Minus 191508-193220
403895 7381715 Minus 3502-4002,4070-4308
403977 7657840 Minus 115573-115820
404043 9558573 Plus 29042-29135,46597-46699
404059 3548785 Plus 104326-106788
404076 9931752 Minus 3848-3967
404196 3805917 Minus 67928-68109
404249 8655533 Plus 64270-64633
404257 9367215 Plus 15262-16227
404285 2326514 Plus 32282-32416
404288 2769644 Plus 3512-3691
404367 9965011 Minus 114391-114628
404443 7579073 Minus 87198-87441
404453 7657714 Plus 27768-29179
404476 8080699 Plus 101841-102043
404513 8151941 Minus 112837-113339
404561 9795980 Minus 69039-70100
404569 7249169 Minus 104257-104348,104822-104970
404577 4020145 Plus 17991-18420
404588 6456726 Minus 40059-40210
404599 8705107 Plus 110443-110733
404604 9212537 Minuε 72019-72509
404638 9796751 Minuε 99433-99528,100035-100161
404767 7882827 Minuε 23244-23759
404793 7232206 Minuε 61087-61590
404822 3810614 Plus 7541-8132
404834 6911603 Minus 37948-38226
404845 7958980 Minus 47174-47326,52928-53146,53312-53602
404898 7331420 Minus 177015-177328
404936 6850774 Plus 191519-191664
404957 7407927 Plus 147512-148011
405017 6532084 Plus 35551-35690
405059 7656683 Plus 349-822
405090 8072525 Minus 38552-39202
405093 8072575 Plus 95878-96020
405120 8099940 Plus 140176-140340
405170 9966524 Plus 37047-37198
405229 7249019 Plus 51081-51701
405230 7249032 Minus 97493-97682 405233 7249045 Plus 9588-10065
405241 7249178 Minus 69927-70526
405264 7329374 Plus 28556-28684
405287 3928029 Plus 8980289999
405302 2078453 Minus 121688-121840
405303 2078453 Minus 130607-130802
405336 6094635 Plus 33267-33563
405347 2979602 Minus 977-1116
405385 6552772 Plus 48332-48454
405443 7408143 Pluε 9071690887,101420101577
405455 7656675 Plus 134112-134671
405494 8050952 Minus 70284-70518
405521 9454643 Plus 6509665247,7750877637,8124281364,8424684395
405523 9454643 Plus 114550-114688,117265-117407,119490119599,123237-123395131140-131217
405547 1054740 Plus 124361-124520,124914-125050
405605 5836195 Minus 117070-117270
405608 5815499 Minus 66822-66925
405629 4508116 Minus 101678-101866
405634 5306288 Plus 17856-17957,18302-18412,18837-18927,22790-22989
405654 4895155 Minus 53624-53759
405692 4314424 Plus 6137962562
405706 4165003 Plus 44307-44431,4961949802
405720 9797144 Plus 13409-13861
405732 7534017 Plus 146981-147316
405759 3288022 Minus 18283-18399
405780 7248203 Minus 48204-48371
405784 7417368 Minus 77798-78000
405829 7109593 Minus 15628-16127
405869 6758731 Minuε 89867-90358
405935 6758795 Minus 163112-163652
405959 6758815 Plus 1642
405965 8247786 Minus 179930180373
405966 8247788 Minus 51762-51978
405970 8247789 Minuε 4579546295
405981 8247790 Pluε 4771-5338
406005 8247801 Minuε 39912-40220
406053 6758997 Plus 30921-31532
406073 9119150 Plus 60495-60610
406091 9123919 Minus 197370197935
406092 9123919 Plus 251370-251797,252168-252882
406298 5686278 Minus 30084-30770
406327 9212407 Pluε 168241-168492
406333 9213235 Pluε 64689-64798
406364 9256114 Minus 50715-50833
406377 9256135 Plus 126826-126979,129755-129942
406413 9256407 Plus 4385844003,46993-47136
406468 9795553 Plus 4373-4616,88709046,11366-11509,11625-11880
406470 9795562 Minus 15532-15697
406504 7711360 Minus 107068-107277
406506 7711374 Minuε 6843-8077F
406592 4567182 Plus 352560-352963
Table 32A lists about 969 genes upregulated in lung fibrosis relative to normal body tissues Types of pulmonary fibrosiε εampleε included in this analysis were idiopathic pulmonary fibrosiε (IPF), hypersensitivity pneumonitis (HP), and non εpxific interstitial pneumonitis (NSIP) These genes were selxted from 59680 probesetε on the Eos/Affymetnx Hu03 Genxhip aπay Gene expression data for exh probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative levels of mRNA expresεion
Table 33A lists about 800 genes upregulated in lung fibrosis relative to normal lung Types of pulmonary fibrosis samples included in this analysis were idiopathic pulmonary fibrosis (IPF), hypersensitivity pneumonitis (HP), and non-spxific interstitial pneumonitis (NSIP) These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expreεεion data for each probeset obtained from this analysis mas expressed as average intensity (Al), a normalized value reflxting the relative levels of mRNA expression
Table 34A lists about 703 genes upregulated in idiopathic pulmonary fibrosis (IPF) relative to hypersensitivity pneumonitis (HP) or non-spxific interstitial pneumonitis (NSIP) These genes were selected from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expresεion data for exh probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative levels of mRNA expreεεion
Table 35A lists about 323 genes upregulated in hypersensitivity pneumonitis (HP) relative to idiopathic pulmonary fibrosis (IPF) or non-spxific interstitial pneumonitis (NSIP) These genes were selected from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expression data for each probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative levels of mRNA expression
Table 36A lists about 52 genes upregulated in non-specific interstitial pneumonitis (NSIP) relative to hypersensitivity pneumonitis (HP) or idiopathic pulmonary fibrosis (IPF) These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expression data for each probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative levels of mRNA expreεεion
Table 37A lists about 206 genes downregulated in lung fibrosis relative to normal lung Types of pulmonary fibrosis samples included in this analysis were idiopathic pulmonary fibrosiε (IPF), hypersensitivity pneumonitis (HP), and non specific interstitial pneumonitis (NSIP) These genes were selxted from 59680 probesets on the Eoε/Affymetπx Hu03 Genxhip array Gene expression data for each probeset obtained from this analysis was expresεed as average intensity (Al), a normalized value reflxting the relative levels of mRNA expression Table 38A lists about 207 genes upregulated in lung fibrasis relative to normal tisεueε Typeε of pulmonary fibrosis samples included in this analysis were idiopathic pulmonary fibrosis (IPF), hypersensitivity pneumonitis (HP), and non specific interstitial pneumonitis (NSIP) These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genechip array Gene expression data for each probeset obtained from this analysiε was expresεed as average intensity (Al), a normalized value reflecting the relative levels of mRNA expression
TABLE 32A About 969 genes upregulated in lung fibrosis relative to normal body tisεues
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number UnigenelD Unigene number Unigene Title Unigene gene title
R1 90th percentile of lung fibrosiε Als divided by 90th percentile of normal tissue Als, where the minimum value for the numerator and denominator was set to 50
R2 90th percentile of lung fibrosis Als divided by 90th percentile of normal tissue Als, where the 15th percentile of normal tissue Als was subtrxted from both the numerator and denominator The minimum value for the numerator and denominator was set to 50
Pkey ExAccn UnigenelD Unigene Title R1 R2
414517 M24461 Hs 76305 surfactant, pulmonary associated protein 2245 2863
406964 M21305 FGENES predicted novel sxreted protein 16 10 765
431723 AW058350 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 15 83 1486
442275 AW449467 Hs 54795 ESTs 15 74 21 96
417204 N81037 Hs 1074 surfxtant, pulmonary-associated protein 1383 3453
444342 NM 014398 Hs 10887 similarto lysosome assxiated membrane 1240 738
431089 BE041395 ESTs, Weakly similar to unknown protein 1238 605
421110 AJ250717 Hs 1355 cathepsin E 11 86 649
457200 U33749 Hs 197764 thyroid transcription factor 1 11 38 979
425211 M18667 Hs 1867 progastncsin (pepsinogen C) 1089 1594
443709 AI082692 Hs 134662 ESTs 1084 827
431164 AA493650 Hs 94367 Homo sapiens cDNA FLJ23494 fis, clone L 1006 892
445537 AJ245671 Hs 12844 EGF like-domain, multiple 6 996 543
432519 AI221311 Hs 130704 ESTs, Weakly similar to BCHUIA S-100 pro 990 787
421798 N74880 N-acylsphingosme amidohydrolase (acid c 938 835
400269 Eos Control 903 648
444325 AW152618 Hs 16757 ESTs 8 31 676
416402 NM 000715 Hs 1012 complement component 4-bιndιng protein, 8 14 551
413048 M93221 Hs 75182 mannose receptor, C type 1 770 409
432985 T92363 Hs 178703 ESTs 756 783
443324 R44013 Hs 164225 ESTs 706 447
449494 AW237014 Hs 315369 Homo sapiens cDNA FLJ23075 fis, clone L 690 289
408562 AI436323 Hε 31141 roundabout (axon guidance rxeptor, Dros 688 400
449523 NM 000579 Hs 54443 chemokine (C-C motif) receptor 5 656 425
421952 AA300900 Hs 98849 dynein light chain 2B (DNLC2B) 646 447
427383 NM 005411 Hs 177582 surfactant pulmonary-associated protein 630 1357
409203 AA780473 Hs 687 cytxhrome P450, subfamily IVB, polypept 6 28 338
441835 AB036432 Hs 184 advanced glycosylation end product-εpxi 599 1326
446428 AW082270 Hs 12496 ESTε, Weakly similarto ALU4_HUMAN ALU S 588 410
415323 BE269352 Hs 949 neutrophil cytosolic factor 2 (65kD, chr 588 335
442652 AI005163 Hs 201378 ESTs, Weakly similarto T12545 hypotheti 587 569
414812 X72755 Hs 77367 monokine induced by gamma interferon 584 334
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial 572 590
421502 AF111856 Hs 105039 solute earner family 34 (sodium phospha 559 689
436954 AA740151 Hs 130425 ESTs 558 472
446998 N99013 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 548 533
421340 F07783 Hs 1369 dxay xcelerating fxtor for complement 548 269
420656 AA279098 Hs 187636 ESTs 545 399
432441 AW292425 Hs 163484 intron of hepatocyte nuclear factor-3 al 538 365
408380 AF123050 Hs 44532 diubiquitm ι537 311
414998 NM.002543 Hs 77729 oxidised low density lipoprotein (Ixtin 530 398
446921 AB012113 Hs 16530 small inducible cytokine subfamily A (Cy 529 400
429732 U20158 Hs 2488 lymphxyte cytosolic protein 2 (SH2 doma 528 248
442832 AW206560 Hs 253569 ESTs 5 20 378
407949 W21874 Hs 247057 ESTs, Weakly similar to 2109260A B cell 511 381
433293 AF007835 Hε 32417 hypothetical protein MGC4309 511 288
424310 AA338648 Hs 50334 testes development-related NYD-SP22 507 346
428043 T92248 Hs 2240 uteroglobin 506 946
431745 AW972448 Hs 163425 ESTs 504 416
444527 NM 005408 Hs 11383 small inducible cytokine subfamily A (Cy 504 368
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 502 426
419231 AL046294 Hs 136245 ESTs, Weakly similar to T17227 hypotheti 497 335
428927 AA441837 Hs 90250 ESTs 492 315
432222 AI204995 gb an03c03 x1 Stratagene εchizo brain S1 479 305
442994 AI026718 Hs 16954 ESTε 476 265
416030 H15261 Hs 21948 ESTs 476 426
438873 AI302471 Hs 124292 Homo sapiens cDNA FLJ23123 fis, clone L 473 324
453142 AA033648 Hs 7473 ESTs 466 292
424917 AI636208 Hs 96901 hypothetical protein FLJ23049 464 488
439750 AL359053 Hs 57664 Homo sapiens mRNA full length insert cDN 460 260
432810 AA863400 ESTs 454 242
418259 AA215404 ESTs 454 254
453310 X70697 Hs 553 solute carrier family 6 (neurotransmitte 448 486
424144 AA454033 Hε 41644 AKAP-assoαated sperm protein 446 362
423575 C18863 Hs 163443 intron of peπostιn(OSF-2os) 444 341
428667 AI375550 Hs 346868 nucleolar protein p40, homolog of yeast 442 341 428228 AI553633 ESTs 432 298
432435 BE218886 Hs 282070 ESTs 430 226
446932 AA961459 Hs 125644 ESTs 430 2 81
408369 R38438 Hs 182575 SLC15A2 Solute carrier family 15 (H+/pep 430 239
409435 AI810721 Hs 95424 ESTs 430 260
419490 NM 006144 Hs 90708 granzyme A (granzyme 1 , cytotoxic T-lymp 429 248
452561 AI692181 Hs 49169 KIAA1634 protein 423 226
427698 AW972594 Hs 335499 ESTs 422 349
431433 X65018 Hs 253495 surfxtant pulmonary-associated protein 422 1334
446608 N75217 Hs 257846 ESTs 420 362
428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy 4 18 3 14
459702 AI204995 gb an03c03 x1 Stratageπe schizo brain S1 416 264
445885 AI734009 Hs 127699 KIAA1603 protein 416 399
430280 AA361258 Hs 237868 interleukin 7 receptor 413 279
425259 AL049280 Hs 155397 Homo sapiens mRNA, cDNA DKFZp564K143 (fr 412 219
427019 AA001732 Hs 173233 hypothetical protein FLJ10970 412 302
420556 AA278300 Hs 124292 Homo sapiens cDNA FLJ23123 fis, clone L 408 3 13
428467 AK002121 Hs 184465 hypothetical protein FLJ 11259 408 348
432731 R31178 Hs 287820 fibronectin 1 406 266
439398 AA284267 Hs 221504 ESTs 406 2 86
409153 W03754 Hs 50813 hypothetical protein FLJ20022 405 351
412584 X54870 Hs 74085 DNA segment on chromosome 12 (unique) 24 404 244
436120 AI248193 Hs 119860 ESTs 404 3 11
407910 AA650274 Hs 41296 fibronectin leucine πch transmembrane p 403 269
421462 AF016495 Hs 104624 aquapoπn 9 400 251
443257 AI334040 Hs 11614 HSPC065 protein 400 261
421659 NM 014459 Hs 106511 protocadhenn 17 400 300
424273 W40460 Hs 144442 phospholipase A2, group X 398 230
415457 AW081710 Hs 7369 ESTs, Weakly similar to ALULHUMAN ALU S 397 336
450656 AA010539 Hs 18912 ESTs 396 437
429784 M89796 Hs 30 membrane spanning 4-domaιns, εubfamily A 394 244
424527 AW138558 Hs 334873 ESTs, Weakly similar to I54374 gene NF2 393 308
413385 M34455 Hε 840 indoleamine-pyπole 2,3 dioxygenase 392 353
452416 AA026115 Hε 114777 ESTs 392 2 90
428434 AW363590 Hε 65551 Homo sapiens, Similar to DNA segment, Ch 390 506
452281 T93500 Hε 28792 Homo sapiens cDNA FLJ11041 fis, clone PL 390 200
453204 R10799 Hε 191990 ESTs 390 222
450696 AI654223 Hs 16026 hypothetical protein FLJ23191 381 382
422173 BE385828 Hs 250619 phorbolin like protein MDS019(CEM15) 380 2 23
425638 NM 012337 Hs 158450 nasopharyngeal epithelium specific prote 378 286
406672 M26041 Hs 198253 major histxompatibility complex class 378 370
457411 AW085961 Hs 130093 iroquois-class homeobox protein IRX2 376 256
432606 NM.002104 Hs 3066 granzyme K (serine protease, granzyme 3, 376 276
436260 BE172762 Hs 292710 ESTs, Weakly εimilar to ALU5_HUMAN ALU S 374 283
414821 M63835 Hs 77424 Fc fragment of IgG, high affinity la, re 372 255
428820 AA436187 Hs 172631 integπn, alpha M (complement component 371 225
458079 AI796870 Hs 54277 DNA εegment on chromoεome X (unique) 992 370 226
419556 U29615 Hs 91093 chitinase 1 (chitotπosidase) 3 69 771
417412 X16896 Hs 82112 interleukin 1 rxeptor, type I 368 2 17
426174 AA547959 Hs 115838 ESTs 365 293
408727 AL137259 Hs 47115 hypothetical protein DKFZp434D0513 364 262
435990 AI015862 Hs 131793 ESTs 362 227
427621 BE621182 Hs 179882 hypothetical protein FLJ12443 362 348
425555 AA359291 Hs 130767 Homo sapiens cDNA FLJ23553 fis, clone L 361 318
419086 NM.000216 Hs 89591 Kallmann syndrome 1 sequence 360 305
426116 AA868729 Hs 144694 ESTs 360 280
419235 AW470411 Hs 288433 neurotπmin 3 58 288
424054 AA334511 Hs 26638 embrane-εpannlng 4-domaιns, subfamily A 356 258
422667 H25642 ESTs 355 244
406673 M34996 Hs 198253 major histxompatibility complex, claεε 354 398
414142 AW368397 Hs 334485 hemιcentιn(fibulιn 6) 354 330
428330 L22524 Hs 2256 matnx metalloproteinase 7 (matπlysm, 354 311
430832 AI073913 Hε 100686 ESTs, Weakly similar to JE0350 Antenor 353 238
417318 AW953937 Hs 240845 ESTs 352 202
456034 AW450979 gb Ul-H BI3-ala-a 12-0-UI s1 NCI_CGAP.Su 3 50 321
415992 C05837 Hs 145807 hypothetical protein FLJ13593 348 235
430709 R34356 gb yh85d01 s1 Soares placenta Nb2HP Homo 348 213
440273 AI805392 Hs 325335 Homo sapiens cDNA FLJ23523 fis, clone L 347 293
424711 NM 005795 Hs 152175 calcitonin rxeptor-like 347 269
418832 X04011 Hs 88974 cytxhrome b-245, beta polypeptide (chro 346 231
416847 L43821 Hs 80261 enhancer of filamentation 1 (cas-like do 346 237
448019 AW947164 Hs 195641 ESTs, Moderately similar to 138022 hypot 345 207
447183 A1554733 Hs 173182 ESTs 342 201
435299 AI745458 Hs 343026 ESTs, Weakly similar to T20593 hypotheti 340 349
425922 AL157466 Hs 162751 Homo sapiens mRNA, cDNA DKFZp761E2423 (f 340 242
413714 A1560944 Hs 71428 ESTs 338 252
407361 AA744622 Hs 292645 ESTs, Weakly similar to ALU5.HUMAN ALU S 3 36 213
436043 AW963838 Hs 168830 Homo sapiens cDNA FLJ12136 fis clone MA 336 241
450330 AW500775 Hs 24817 hypothetical protein FLJ20136 336 206
407756 AA116021 Hs 38260 ubiquitin spxific protease 18 3 35 242
410606 AW418779 Hs 114889 ESTs 335 239
450726 AW204600 retinoic acid rxeptor, alpha 334 635
430573 AA744550 Hs 136345 ESTs 3 33 1 94 421585 U95626 Hs 302043 chemokine (C-C motif) rxeptor-like 2( 332 275
433658 L03678 Hs 156110 immunoglobulin kappa constant 331 222
454076 AW204712 Hs 61957 ESTs 331 1 95
452039 AI922988 Hs 172510 ESTs 330 295
454024 AA993527 Hs 293907 hypothetical protein FLJ23403 330 237
430414 AW365665 Hs 120388 ESTs 330 248
417958 AA767382 Hs 193417 ESTs 330 204
423001 AA320014 Hs 208603 ESTs 329 262
443774 AL117428 Hs 9740 DKFZP434A236 protein 328 235
424084 AI940675 Hε 20914 hypothetical protein FLJ23056 328 205
424238 AA337401 Hs 137635 ESTs 328 245
429819 AL133011 Hs 225108 Homo sapienε mRNA, cDNA DKFZp434P201 (fr 327 263
448869 AI792798 Hs 12496 ESTε, Weakly similar to ALU4.HUMAN ALU S 326 267
426083 AW962712 Hs 126712 ESTs, Weakly similar to AF191020 1 E2IG5 326 204
451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 322 236
440452 AI925136 Hs 55150 ESTs, Weakly similar to CAYP.HUMAN CALCY 322 387
422109 S73265 Hs 1473 gastπn releasing peptide 320 279
430378 Z29572 Hε 2556 tumor nxrosis factor rxeptor superfami 320 230
413802 AW964490 Hs 32241 ESTs, Weakly similar to S65657 alpha-1 C- 318 242
408761 AA057264 Hs 238936 ESTε, Weakly similar to (defline not ava 318 212
438568 R98865 Hs 11135 major histxompatibility complex, class 318 386
451497 H83294 Hs 284122 Wnt inhibitory factor-1 3 18 299
444034 AL161957 Hs 10177 plxkstπn homology domain interacting p 3 17 202
446094 AK001760 Hs 13801 KIAA1685 protein 317 242
442048 AA974603 gb op34f05 ε1 Soares_NFL_T_GBC_S1 Homo s 3 17 227
406685 M18728 gb Human nonspxitic crossreacting antig 317 280
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 316 1 95
424943 AU077260 Hs 153924 death asε∞iated protein kinaεe 1 316 218
436805 AA731533 Hs 270751 ESTs 3 16 1 95
412610 X90908 Hs 74126 fatty acid binding protein 6, ileal (gas 3 15 363
409799 D11928 Hs 76845 phosphosenne phosphatase-like 3 14 1 74
448140 AF146761 Hs 20450 BCM like membrane protein prxursor 3 13 335
420729 AW964897 Hs 290825 ESTε 312 209
419839 U24577 Hs 93304 phospholipaεe A2, group VII (platelet ac 3 12 206
416580 T61572 Hs 79385 Human clone 23574 mRNA εequence 3 12 258
451820 AW058357 Hε 199248 ESTs 3 10 226
440028 AW473675 ESTs, Weakly similar to T17227 hypotheti 310 301
448030 N30714 Hε 325960 membrane-spanning 4-domaιns εubfamily A 310 232
437866 AA156781 metallothionem 1E (functional) 310 180
428513 BE220806 Hε 184697 plexin C1 310 211
438607 AW080237 Hs 252884 ESTs 310 220
445034 AW293376 Hs 143659 ESTs 308 281
458332 AI000341 ESTs 308 1 87
415083 AI632683 Hs 27179 Homo sapiens cDNA FLJ12933 fis, clone NT 308 1 87
407930 AA045847 Hs 188361 Homo sapienε cDNA FLJ12807 fiε, clone NT 308 1 94
407192 AA609200 gb af12e02 s1 Soares_testιs_NHT Homo sap 307 212
452960 AK001335 Hs 31137 protein tyrosine phosphatase, rxeptor t 307 216
425509 AF079363 Hs 158213 sperm assxiated antigen 6 306 2 5
431087 H12723 Hs 290791 ESTs 306 241
452235 AL039743 Hs 28514 testes development-related NYD-SP21 306 264
449328 AI962493 ESTs 306 278
422900 AA641201 Hs 222051 ESTs 305 1 87
414888 AL039185 Hs 77558 thyroid hormone rxeptor ιnteractor7 305 199
430250 NM 016929 Hs 283021 chloπde intracellular channel 5 305 249
437527 AI241019 Hs 145644 ESTs 304 217
432340 AA534222 gb nj21d02 s1 NCI CGAP AA1 Homo sapiens 304 178
420495 AI338247 Hs 98314 Homo sapienε mRNA, cDNA DKFZp586L0120 (f 302 243
445495 BE622641 Hs 38489 ESTε, Weakly similar to I38022 hypotheti 302 177
411252 AB018549 Hs 69328 MD 2 protein 302 195
439981 AI348408 Hs 124675 ESTs, Weakly similar to T14742 hypotheti 302 224
420683 AA830168 Hs 271305 ESTs 301 214
412095 AI624707 Hs 5921 Homo sapienε cDNA FLJ21592 fis, clone C 300 213
410434 AF051152 Hs 63668 toll like rxeptor 2 300 260
436396 AI683487 Hs 152213 wingless-type MMTV integration site fami 300 1 94
434194 AF119847 Homo εapiens PRO1550 mRNA, partial eds 300 1 81
435800 AI248285 Hs 118348 ESTs 300 189
420000 AB036063 Hs 94262 p53-ιnducιble ribonucleotide reductase s 300 208
449057 AB037784 Hs 22941 KIAA1363 protein 300 218
413195 AA127382 Hs 22404 protease, seπne, 12 (neurotrypsm, moto 299 246
436198 AK001125 Homo sapiens cDNA FLJ10263 fis, clone HE 299 276
411492 T46848 Hs 70337 immunoglobulin superfamily, member 4 299 216
444020 R92962 Hs 35052 ESTs 298 221
427785 X81053 Hs 180828 collagen, type IV, alpha 4 298 208
432583 AW023624 Hs 162282 potassium channel TASK-4, potassium chan 298 240
457675 AF119917 Hs 306574 Homo sapiens PRO3098 mRNA, complete eds 296 203
414646 AA353776 Hs 901 CD48 antigen (B-cell membrane protein) 2 96 174
429950 AW081608 Hs 105053 ESTs 296 240
420394 AB023161 Hs 97403 KIAA0944 protein 2 95 246
406698 X03068 Hs 73931 major histxompatibility complex class 295 413
419038 AW134924 Hs 190325 ESTs 294 172
449765 N92293 Hs 206832 ESTε, Moderately similar to ALU8.HUMAN A 294 293
418293 AI224483 Hs 16063 hypothetical protein FLJ21877 294 1 94
400880 NM.000611* Homo sapiens CD59 antigen p18 294 174 430382 AA477908 Hs 282267 ESTε, Moderately similar to I38022 hypot 294 212
419034 NM 002110 Hs 89555 hemopoietic cell kinase 293 2 25
439335 AA742697 Hs 62492 NM_052863 Homo sapiens secretoglobm, fa 293 372
429597 NM 003816 Hs 2442 a disintegnn and metalloproteinase doma 292 1 91
419981 AA897581 Hs 128773 ESTs 292 218
400419 AF084545 Target 292 1 83
435176 AA744875 Hs 189413 ESTs 291 215
413283 R78669 Hs 23756 hypothetical protein similar to swine ac 290 225
444339 T96555 Hs 31562 ESTs 290 316
429272 W25140 Hs 110667 ESTs 290 243
435047 AA454985 Hs 54973 cadhenn like protein VR20 290 229
435080 AI831760 Hs 155111 hypothetical protein FLJ14428 290 240
402474 NM 004079 Homo sapiens cathepsin S (CTSS 288 247
421554 AW137676 Hs 97775 Esfs 288 337
422770 AL117544 Hs 120021 DKFZP434I092 protein 288 200
434658 AI624436 Hs 310286 ESTs 288 206
440248 AA876138 ESTs 286 224
442006 AW975183 ESTs Weakly similar to S72482 hypotheti 286 432
430515 AA746503 Hs 283313 ESTs 286 296
446063 AI720140 Hs 151079 ESTs 286 247
438177 BE327015 ESTs 286 1 70
429083 Y09397 Hs 227817 BCL2-related protein A1 285 206
417105 X60992 Hs 81226 CD6 antigen 285 300
433230 AW136134 Hε 220277 ESTs 284 1 97
438676 AA813745 Hε 123446 ESTs 284 262
435575 AF213457 Hs 44234 triggering receptor expresεed on myeloid 282 433
420252 AW270404 Hs 193161 ESTε 282 322
415788 AW628686 Hs 78851 KIAA0217 protein 2 82 1 78
428065 AI634046 Hs 157313 ESTε 281 247
434340 AI193043 Hs 128685 ESTε, Weakly similar to T17226 hypotheti 281 267
451558 NM.001089 Hε 26630 ATP-bmding cassette, sub-family A (ABC1 278 339
435517 AA928626 Hs 130177 ESTs 278 236
439883 AL359652 Hs 171096 Homo sapiens EST from clone DKFZp434A041 278 1 82
434158 T86534 Hs 14372 ESTs 278 1 96
428923 BE047698 Hs 188785 ESTs 278 207
413786 AW613780 Hs 13500 ESTs 278 1 97
406387 Target Exon 277 422
421168 AF182277 Hs 330780 cytxhrome P450, subfamily HB (phenobar 276 324
444561 NM 004469 Hs 11392 c-fos induced growth fxtor (vaεcular en 276 211
427484 N32859 Hs 37288 nuclear receptor εubfamily 1, group D, m 276 1 94
417728 AW138437 Hs 24790 KIAA1573 protein 276 1 78
435154 AA668764 \ ESTε 276 210
429490 AI971131 Hs 23889 ESTs, Weakly similar to ALU7_HUMAN ALU S 276 221
423387 AJ012074 vasoxtive intestinal peptide receptor 1 276 236
432060 AW971364 Hs 324775 ESTs 275 202
434164 AW207019 Hs 148135 seπne/threonine kinase 33 274 248
423706 U95218 Hs 131924 G protein-coupled rxeptor 65 274 1 93
442703 AL044949 Hs 116298 ESTε 274 1 89
450247 AF123303 Hs 24713 hypothetical protein 274 1 73
430998 AF128847 Hs 204038 indolethylamine N-methyltransferase 274 285
426535 AU077012 Hs 288582 ESTs, Weakly similar to ubiquitous TPR m 274 1 88
409196 NM 001874 Hs 334873 carboxypeptidase M 273 1 86
422389 AF240635 Hs 115897 protocadhenn 12 2 2 226
444324 AI301330 Hs 143838 ESTs 272 1 74
417831 H16423 Hs 82685 CD47 antigen (Rh-related antigen, integr 272 240
428769 AW207175 Hs 106771 ESTs 272 219
404277 NM 019111* Homo sapiens major histocompa 272 3 12
409653 AW451693 Hs 220826 ESTs 272 262
437211 AA382207 Hs 5509 xotropic viral integration site 2B 272 225
430299 W28673 Hs 106747 seπne carboxypeptidase 1 prxursor prot 272 209
444381 BE387335 Hs 283713 hypothetical protein BC014245 271 226
443547 AW271273 hypothetical protein FLJ12666 271 1 74
408741 M73720 Hs 646 carboxypeptidase A3 (mast cell) 270 239
402674 Target Exon 270 1 95
438068 AI927209 Hs 306210 Homo sapiens cDNA FLJ23133 fis, clone L 270 223
415075 L27479 Hs 77889 Fnedreich ataxia region gene X123 269 211
444314 AI140497 gb ow76b09 s1 Soares fetal lιver_spleen_ 269 228
428656 AB037798 Hs 188790 KIAA1377 protein 268 1 91
418883 BE387036 Hs 1211 xid phoεphataεe 5, tartrate reεistant 268 395
443951 F13272 femtiπ, light polypeptide 268 266
427581 NM.014788 Hs 179703 KIAA0129 gene product 268 1 74
432639 AW973785 gb EST385886 MAGE resequences, MAGM Homo 268 1 78
446423 AW139655 Hs 150120 ESTs 268 229
407939 W05608 Hs 312679 ESTs, Weakly similar to A49019 dynein he 267 207
431779 AW971178 Hs 268571 apolipopratem C-l 267 300
458124 AW005548 Hs 124590 ESTs 267 378
432882 NM 013257 Hs 279696 serum/glucxorticoid regulated kinase-h 266 1 64
445745 AB007924 Hs 13245 KIAA0455 gene product 266 1 64
425188 AK002052 Hs 155071 hypothetical protein FLJ11190 265 1 92
432231 AA339977 Hs 274127 CLST 11240 protein 264 423
442200 AW590572 Hs 235768 ESTs 264 246
426828 NM.000020 Hs 172670 activin A rxeptor type II like 1 264 200
448569 BE382657 Hε 21486 signal transducer and xtivator of trans 263 323 425955 T96509 Hs 248549 ESTs, Moderately similar to S65657 alpha 263 248
411213 AA676939 Hs 69285 πeuropilin 1 262 1 73
439737 AI751438 Hs 41271 Homo sapiens mRNA full length insert cDN 262 269
446570 AV659177 Hs 127160 ESTs 261 244
411020 NM 006770 Hs 67726 macrophage receptor with collagenouε εtr 260 339
434792 AA649253 Hs 132458 ESTε 260 1 74
426782 R14614 Hs 33846 ESTε 260 236
425371 D49441 Hs 155981 mesolhelin 260 697
447720 AL038765 Hs 161304 ESTs 259 306
444623 AI183829 Hs 202111 ESTs 259 277
433376 AI249361 HS 74122 caspase 4, apoptosis related cysteine pr 258 201
444542 AI161293 Hs 280380 aminopeptidase 258 231
439549 AW937885 Hs 137314 ESTs 258 237
431385 BE178536 Hs 11090 membrane spanning 4-domaιns, subfamily A 258 256
417015 M83772 Hs 80876 flavin containing onooxygenase 3 256 247
433308 AA582718 Hs 291650 ESTs 256 201
443885 H91806 Hs 15284 ESTs 255 1 71
408170 AW204516 Hs 31835 ESTs 255 1 59
456844 AI264155 Hs 152981 CDP-diacylglycerol synthase (phosphatida 254 1 63
412104 AW205197 Hs 240951 Homo sapienε, Similar to RIKEN cDNA 2210 254 298
428791 AA435661 Hs 264750 ESTs 253 229
435472 AW972330 Hε 283022 tπggeπng rxeptor expressed on myeloid 253 391
447357 AI375922 Hs 159367 ESTs 252 283
431393 AW971493 Hs 134269 ESTs, Highly similar to cytokine recepto 252 1 90
424105 AI142336 Hε 43977 Human DNA sequence from clone RP11-196N1 252 345
408308 AL033377 Hs 44197 hypothetical protein DKFZp564D0462 252 1 98
438698 AW297855 ESTs, Weakly similar to I38022 hypotheti 252 1 98
420991 AW504814 Hs 287379 Homo sapiens mRNA for FLJ00111 protein, 252 241
424049 AB014524 Hs 138380 KIAA0624 protein 251 2 19
438543 AA810141 Hs 192182 ESTs 251 206
414061 NM 000699 Hs 335493 a ylase, alpha 2A pancreatic 251 214
424806 AA382523 Hs 105689 MSTP031 protein 251 211
438580 AA811262 Hs 299202 ESTs 250 1 83
434445 AI349306 Hs 11782 ESTs 250 313
444001 AI095087 Hs 152299 ESTs, Moderately similar to S65657 alpha 250 1 76
413638 H71252 gb ys12h12 s1 Soares fetal liver spleen 250 200
421281 AI299139 Hs 17517 ESTs 250 240
441384 AA447849 Hs 288660 retinoic xid induced 3 250 275
436772 AW975688 metallothionem 1E (functional) 249 1 80
433102 AI343966 Hs 158528 ESTs 249 225
430129 BE301708 Hs 233955 hypothetical protein FLJ20401 248 209
445612 N94126 Hs 12969 hypothetical protein 248 228
445261 T79759 Hs 250651 ESTs, Weakly similar to I38022 hypotheti 248 1 87
433854 AA610649 Hs 333239 ESTs 248 209
447997 H00656 Hs 29792 ESTs, Weakly similar to I38022 hypotheti 248 275
411069 AL133092 Hs 68055 hypothetical protein DKFZp434l0428 248 201
440594 AW445167 Hs 126036 ESTs 248 1 57
450295 AI766732 Hs 210628 ESTs 248 1 99
431316 AA502663 Hs 145037 ESTs 248 1 80
438564 AA381553 Hs 198253 major histxompatibility complex, class 248 280
439593 BE073597 Hs 124863 ESTε 248 1 89
422355 AW403724 Hs 300697 coagulation fxtor VII (serum prothrombi 247 374
453134 AA032211 Hs 118493 ESTs 246 272
417169 R13550 Hs 21388 ESTs 246 1 88
434411 AA632649 Hs 201372 ESTs 246 1 95
440381 AA917808 Hs 190495 ESTs 246 209
448782 AL050295 KIAA0758 protein 246 269
404240 NM 018950 Homo sapienε major hiεtxompat 245 283
450843 AI741483 Hs 205383 ESTε 244 225
434137 AA907734 Hs 124895 ESTs 244 255
438315 R56795 Hs 82419 ESTε 244 1 94
420802 U22376 Hs 1334 v myb avian myeloblastosis viral oncogen 244 1 61
439402 W02753 Hs 103002 ESTs 244 1 90
445903 AI347487 Hs 132781 clasε I cytokine rxeptor 244 232
437323 AA371145 Hs 194397 leptm rxeptor 244 1 70
433923 AI823453 Hs 146625 ESTs 244 1 58
442201 AW516704 Hs 208726 ESTs 243 1 68
437982 N93466 Hs 121764 ESTs, Weakly similar to testicular tekti 243 322
452698 NM 001295 Hs 301921 chemokine (C-C motif) rxeptor 1 243 221
407904 W44735 Hs 9286 Homo sapienε cDNA FLJ21278 fiε, clone C 243 213
406973 M34996 Hs 198253 major histxompatibility complex, clasε 243 268
428055 AA420564 Hs 101760 ESTs 242 205
428970 BE276891 Hs 194691 retinoic xid induced 3 (RAIG1), etabo 242 279
433138 AB029496 Hs 59729 semaphoπn sem2 242 1 68
415757 AA830854 Hs 187810 ESTs 242 202
438507 AA809052 ESTε 242 208
450811 AI739486 Hs 245497 ESTε 242 1 97
424027 AW337575 Hs 201591 ESTε 242 276
423778 Y09267 Hs 132821 flavin containing monooxygenase 2 241 315
435978 AF272899 Hs 135118 Homo sapiens PR-domain zinc finger prote 241 208
426291 U58913 Hs 169191 small inducible cytokine subfamily A (Cy 240 1 76
416370 N90470 Hs 203697 CD38 antigen (p45) 240 1 97
415688 AA166963 gb zo86d01 s1 Stratagene ovanan cancer 240 1 63 445633 AI453386 Hs 17287 ESTs, Weakly similar to S26689 hypotheti 239 1 99
431300 AA502346 gb ne26b03 ε1 NCI_CGAP_Co3 Homo sapiens 239 1 79
407690 R47799 Hs 266957 hypothetical protein FLJ14281 239 1 84
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 239 221
425235 AA353113 Hs 112497 Homo sapienε cDNA FLJ22743 fiε, clone H 238 209
451406 AI694320 Hs 6295 ESTs, Weakly similar to T17248 hypotheti 238 1 8
437479 R61866 Hs 101277 ESTs 238 300
445784 AI253155 Hs 146065 ESTs 238 1 61
418300 AI433074 Hs 86682 Homo sapienε cDNA FLJ21578 fis, clone C 238 225
413753 U17760 Hs 75517 laminin, beta 3 (nicem (125kD), kalmin 237 1 55
418945 BE246762 Hs 89499 arachidonate 5-lιpoxygenase 237 241
416140 AI918035 Hs 301198 roundabout (axon guidance receptor, Dros 237 1 61
418262 Z38968 ESTs 237 205
420943 AI718702 Hs 279930 major histxompatibility complex, clasε 237 200
442762 AF035119 Hs 8700 deleted in liver cancer 1 237 205
429747 M87507 Hs 2490 caεpase 1, apoptosis related cysteine pr 237 1 67
420460 AA262331 Hs 48376 Homo sapiens clone HB-2 mRNA sequence 236 1 88
420137 AA306478 Hs 95327 CD3D antigen, delta polypeptide (TιT3 co 236 261
439018 AW300887 Hs 26638 membrane spanning 4-domaιns, subfamily A 236 284
427250 R35941 Hs 25418 ESTs 236 215
452194 AI694413 olfactory receptor, family 2, subfamily 236 341
411027 AF072099 Hs 67846 leukocyte immunoglobulin like rxeptor, 236 305
407242 M18728 gb Human nonspecific crosεreacting antig 235 234
418875 W19971 Hs 233459 ESTε 235 1 95
425023 AW956889 Hs 154210 EDG-1 (endothelial differentiation, sph 235 1 85
432608 AI492660 Hs 170935 ESTs 235 206
408048 NM 007203 Hs 42322 A kinase (PRKA) anchor protein 2 235 1 91
415189 L34657 Hs 78146 platelet/endothelial cell adhesion molx 235 234
437442 T85104 Hs 222779 ESTs, Moderately similar to similar to N 235 213
410577 X91911 Hs 64639 glioma pathogeπesis-related protein 234 1 73
422099 AA156022 Hs 111518 hypothetical protein 234 1 80
427337 Z46223 Hs 176663 Fc fragment of IgG, low affinity lllb, r 234 224
427541 AI798983 Hs 82921 εolute camerfamily 35 (CMP-εialic aci 233 262
420899 NM 001629 Hs 100194 arachidonate 5-lιpoxygenase-actιvatιng p 232 252
431848 AI378857 Hs 271605 ESTs, Highly similar to AF175283 1 zinc 232 250
446354 AW449650 ESTs 232 221
423354 AB011130 Hs 127436 calcium channel, voltage-dependent, alph 232 434
423961 D13666 Hs 136348 peπostιn(OSF-2os) 231 219
410798 BE178622 Hs 16291 gb PM3-HT0605-270200 001-a02 HT0605 Homo 231 234
457250 AA811987 Hs 125779 ESTs 231 1 66
446291 BE397753 Hs 14623 interferon, gamma inducible protein 30 231 286
426839 M74782 Hs 172689 interieukin 3 rxeptor, alpha (low affin 230 212
422746 NM 004484 Hs 119651 glypican 3 230 216
439920 H05430 Hs 288433 neurotπmin 230 406
414942 C14898 Hs 192986 ESTs 230 202
419092 J05581 Hs 89603 mucin 1, transmembrane 229 308
424878 H57111 Hs 221132 ESTs 229 1 84
406687 M31126 matrix metalloproteinase 11 (stromelysin 229 276
411605 AW006831 ESTs 229 1 58
416965 N26223 Hs 160436 ESTs 229 471
428713 AA432067 ESTε, Moderately similarto CYA4 RAT ADE 229 1 73
435106 AA100847 Hs 5978 ESTs, Highly similar to AF174600 1 F-box 228 1 90
420380 AA640891 Hs 102406 ESTs 228 282
407137 T97307 gb ye53h05 s1 Soareε fetal liver spleen 228 1 52
410361 BE391804 Hs 62661 guanylate binding protein 1, iπterferon- 228 209
447160 AA330310 Hs 24181 ESTs 228 1 71
421114 AW975051 Hs 293156 ESTs, Weakly similar to I78885 seπne/th 227 1 98
453686 AL110326 Hs 304679 ESTs, Moderately similar to Z195.HUMAN Z 227 1 91
452114 N22687 Hs 8236 ESTs 227 1 88
417355 D13168 Hs 82002 endothelin rxeptor type B 226 1 63
434927 H46612 Hs 293815 Homo sapienε HSPC285 mRNA, partial cdε 226 1 84
442262 BE170651 Hs 8700 deleted in liver cancer 1 226 1 86
426216 N77630 Hε 13895 Homo εapiens cDNA FU11654 fis, clone HE 226 1 72
425354 U62027 Hs 155935 complement component 3a rxeptor 1 226 170
409190 AU076536 Hs 50984 sarcoma amplified sequence 226 1 56
414221 AW450979 gb UI-H-BI3 ala-a-12-O-UI s1 NCI_CGAP.Su 226 212
435272 AA906415 Hs 110041 ESTs 225 215
414991 C17898 gb C17898 Human placenta cDNA (TFujiwara 224 358
424623 AW963062 Hs 270737 ESTs 224 1 87
424665 AW368576 Hs 139851 caveolm 2 2 24 215
422426 W79117 Hs 58559 ESTs 222 333
413829 NM 001872 Hs 75572 carboxypeptidase B2 (plasma) 222 239
427535 R29543 Hε 2164 pro-platelet basic protein (includes pla 2 22 328
447197 R36075 gb yh88b01 s1 Soares placenta Nb2HP Homo 222 1 59
446142 AI754693 Hε 145968 ESTs 222 1 88
410503 AW975746 Hε 188662 KIAA1702 protein 222 1 56
435523 T62849 Hε 11090 membrane spanning 4-domaιns, subfamily A 222 249
437629 AW574774 Hs 121692 ESTs 2 22 1 70
429688 BE245169 Hs 211610 CUG tnplet repeat, RNA-binding protein 221 1 64
430413 AW842182 Hs 241392 small inducible cytokine A5 (RANTES) 220 273
447033 AI357412 Hs 157601 Predicted gene Eos cloned, secreted w/V 220 258
429496 AA453800 Hs 192793 ESTs 220 297
425516 BE000707 Hs 29567 ESTs 220 1 58 422404 AL133571 Hs 336189 Homo sapiens mRNA cDNA DKFZp434F1135 (f 219 1 92
423526 AB011086 Hs 129739 KIAA0514 gene product 219 285
436485 X59135 Hs 156110 immunoglobulin kappa conεtant 2 19 201
426251 M24283 Hs 168383 intercellular adheεion molecule 1 (CD54) 2 19 253
443441 AW291196 Hs 92195 ESTε 218 1 73
418458 AA332941 Hs 85226 lipase A, lysosomal xid, choleεterol es 2 18 253
408705 AA312135 Hs 46967 HSPC034 protein 218 1 54
419150 T29618 Hs 89640 TEK tyrosine kinase, endothelial (venous 2 18 1 93
430915 AA488953 gb aa55e05 r1 NCI CGAP.GCB1 Homo sapiens 2 18 1 57
418791 AA935633 Hs 194628 ESTs 217 205
432620 AA777749 Hs 5978 UM domain only 7 2 17 1 75
424321 W74048 Hs 1765 lymphocyte-specific protein tyrosine km 217 201
406646 M33600 Hs 308026 major histocompatibility complex, clasε 2 17 312
424450 AL137526 dynein intermediate chain 2 2 17 414
426410 BE298446 Hs 305890 BCL2-lιke 1 216 219
416975 NM 004131 Hs 1051 granzyme B (granzyme 2, cytotoxic T-lymp 216 1 70
421077 AK000061 Hs 101590 hypothetical protein 2 16 1 60
424563 AA446932 Hs 151428 ret finger protein 2 216 1 83
405102 C15001220* gι|4469558|gb|AAD21311 1| (AF 2 16 1 78
452436 BE077546 Hs 31447 ESTs, Moderately similar to A46010 X-lin 215 1 87
416206 AW206248 Hs 111092 hypothetical protein FLJ22332 215 1 65
418067 AI127958 Hs 83393 cystatin E/M 215 240
436372 AW972301 Hs 310286 ESTs 215 235
418728 AW970937 Hs 293843 ESTs 2 14 258
450400 AI694722 Hs 279744 ESTs 214 206
409031 AA376836 ESTs 2 14 214
435143 R12375 Hs 194600 ESTs 214 1 69
444805 AB007899 Hs 12017 homolog of yeast ubiquitin-protein ligas 214 203
453927 AA082465 Hs 125031 cholme/ethanolaminephosphotranεferase 2 14 1 57
418304 AA215702 gb zr97g10 r1 NCI.CGAP.GCB1 Homo sapienε 214 1 68
418299 AA279530 Hs 83968 integnn beta 2 (antigen CD18 (p95), ly 2 14 204
408996 AI979168 Hs 344096 glycoprotein (transmembrane) nmb 213 1 72
417018 M16038 Hs 80887 v-yes-1 Yamaguchi sarcoma viral related 213 1 68
418741 H83265 Hs 8881 ESTs, Weakly similar to S41044 chromosom 2 13 247
452353 C18825 Hs 29191 epithelial membrane protein 2 212 231
418918 X07871 Hs 89476 CD2 antigen (p50), sheep red blood cell 2 12 276
424006 AF054815 Hs 137548 CD84 antigen (leukxyte antigen) 212 211
437581 N59284 Hs 288010 ESTs 2 12 285
410976 R36207 Hs 25092 hypothetical protein MGC10744 212 204
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 212 200
423069 W15613 Hs 1613 adenosine A2a receptor 212 1 72
432860 AW974077 Hs 283349 ESTε 212 175
449509 AA001615 Hs 84561 ESTε 2 12 1 84
456062 AI866286 Hs 71962 ESTε, Weakly similar to B36298 proline r 211 442
419216 AU076718 Hs 164021 small inducible cytokine subfamily B (Cy 2 11 1 65
459680 H96982 Hs 42321 ESTs 211 220
449677 AA002071 gb zh85d01 s1 Soares_fetal_lιver_spleen_ 210 212
443071 AL080021 Hs 8986 complement component 1, q subcomponent 210 248
443021 AA368546 Hs 8904 Ig superfamily protein 210 242
437838 AI307229 ESTs 210 1 67
429421 AL031658 Human DNA sequence from clone RP1-310O13 210 1 91
407202 N58172 Hs 109370 ESTs 210 1 68
443669 AI140462 Hs 134587 ESTs 210 1 64
411990 AW963624 Hs 31707 ESTs, Weakly similar to YEW4.YEAST HYPOT 210 1 71
408410 AA447438 Hs 44697 ATPase, Clasε V, type 10C 210 205
436293 AI601188 Hs 120910 ESTs 210 201
410730 AW368860 DnaJ (Hsp40) homolog, subfamily B, membe 210 166
427876 AI494291 ESTs 210 248
456672 AK002016 Hs 114727 Homo sapiens, clone MGC 16327, mRNA, com 209 311
434987 AW975114 ESTs 209 1 69
433735 AA608955 Hs 109653 ESTs 209 1 78
433226 AW503733 Hs 9414 KIAA1488 protein 209 1 62
425787 AA363867 Hs 155029 ESTs 209 1 85
452304 AA025386 Hs 61311 ESTs, Weakly similar to S10590 cyεteine 208 341
442369 AI565071 ESTs 208 1 60
430478 NM 014349 Hε 241535 apolipoprotein L, 3 208 239
434421 AI915927 Hε 34771 ESTs 208 1 66
415138 C18356 Hs 295944 tisεue fxtor pathway inhibitor 2 208 1 72
431728 NM 007351 Hs 268107 multimeππ 208 1 51
444929 AI685841 Hs 161354 ESTε 208 314
408873 AL046017 calmodulin 2 (phosphorylase kinaεe, delt 208 209
437634 AW293046 Hs 255158 ESTs 208 1 66
400277 Eos Control 208 1 46
443601 AI078554 Hs 42658 ESTs 208 1 87
432212 AW137742 ESTs 208 284
410763 AF279145 Hs 8966 hypothetical protein FLJ21776 207 1 48
406122 Target Exon 206 275
430665 BE350122 Hs 157367 ESTs, Weakly similar to I78885 seπne/th 206 1 66
408788 AL134947 Hs 213956 Homo sapienε BAC clone RP11-102O5 from Y 206 1 70
421057 T58283 Homo sapiens cDNA FLJ22063 fis, clone H 206 1 78
413936 AF113676 Hs 297681 senne (or cysteine) proteinase inhibito 206 230
431924 AK000850 Hs 272203 l Homo sapiens cDNA FLJ20843 fis, clone AD 206 231
449444 AW818436 solute earner family 16 (monxarboxylic 206 1 41 421464 AA291553 Hs 190086 ESTs 206 261
424831 H61453 ESTs 206 212
434542 AA769310 hypothetical protein FLJ13164 206 1 44
418323 NM 002118 Hs 1162 major histocompatibitity complex, class 205 261
418836 AI655499 Hε 161712 ESTs 205 1 73
431315 AW972227 Hs 163986 Homo sapiens cDNA FLJ22765 fis, clone K 205 1 99
400750 Target Exon 205 1 75
406851 AA609784 major histocompalibility complex, clasε 205 394
414936 C14774 gb C14774 Clontech human aorta polyA mRN 205 241
453459 BE047032 Hs 257789 ESTε 204 1 86
443450 N66045 Hs 133529 ESTs 204 246
430015 AW768399 ESTs 204 1 63
429399 AA452244 Hs 16727 ESTs 204 1 51
411653 AF070578 Hs 71168 Homo sapiens clone 24674 mRNA sequence 204 1 73
417916 NM 006416 Hs 82921 solute camerfamily 35 (CMP-sialio aci 204 1 46
421757 Z20897 Hε 296259 paraoxonase 3 204 213
441942 AF182645 Hε 8024 IK cytokine, down regulator of HLA II 204 1 82
431843 AA516420 ESTs, Weakly similar to 138022 hypotheti 204 1 67
432006 AL137382 Hε 272320 Homo sapiens mRNA, cDNA DKFZp434L1226 (f 204 323
414154 AW205314 Hs 323060 ESTs 203 296
449987 AW079749 Hs 184719 ESTs, Weakly similar to ALULHUMAN ALU S 203 1 59
418452 BE379749 Hs 85201 C-type (calcium dependent, carbohydrate- 203 201
406645 M57466 Hs 814 major histocompalibility complex, class 203 249
414516 AI307802 ESTs, Weakly similar to T43458 hypotheti 202 1 56
417032 AA192469 Hs 271838 ESTs 202 1 48
414875 H42679 Hs 77522 major histocompatibility complex, class 202 279
414522 AW518944 Hs 76325 Immunoglobulin J chain 202 1 84
410511 AA743475 Hs 285655 ESTε 202 1 87
423533 NM 014339 Hs 129751 interleukin 17 rxeptor 202 226
437259 AI377755 Hs 120695 ESTε 202 234
426298 AW965058 Hs 111583 ESTε Weakly εimilar to I38022 hypotheti 202 1 86
426722 U53823 Hs 171952 occlud 202 1 57
421229 AI056590 Hs 7086 hypothetical protein MGC12435 202 1 79
410491 AA465131 Hε 64001 Homo sapiens clone 25218 mRNA sequence 202 1 97
447232 AW499834 Hs 327 interleukin 10 rxeptor, alpha 202 209
449317 AW293413 Hs 132906 19A24 protein 202 1 84
439556 AI623752 Hs 163603 ESTs 202 1 62
443031 AW134696 Hs 49418 ESTs 201 1 58
444838 AV651680 Hs 208558 ESTs 201 1 69
453108 AI311457 Hs 99472 ESTs 201 1 64
432967 AA572949 Hs 207566 ESTs 201 1 83
441390 AI692560 Hs 131175 ESTs 201 1 63
448076 AJ133123 Hs 20196 adenylate cyclase 9 201 1 80
420256 U84722 Hs 76206 cadhenn 5, type 2, VE-cadheπn (vascula 201 232
414629 AA345824 Hs 76688 carboxylesterase 1 (monxyte/macrophage 201 1 90
418460 M26315 Hs 85258 CD8 antigen, alpha polypeptide (p32) 201 1 90
415443 T07353 Hs 7948 ESTs 200 1 54
424925 NM.002432 Hε 153837 myeloid cell nuclear differentiation ant 200 274
404394 ENSP00000241075 TRRAP PROTEIN 200 299
459557 N58315 gb yv68g06 s1 Soares fetal liver spleen 200 1 89
437204 AL110216 ESTs, Weakly similar to 155214 salivary 200 1 46
429295 AA682377 Hε 99216 ESTs, Moderately similar to ALU8.HUMAN A 200 1 37
440667 BE076969 Hε 7337 hypothetical protein FLJ 10936 200 1 51
431193 AW749505 Hs 296770 KIAA1719 protein 1 99 201
432485 N90866 Hs 276770 CDW52 antigen (CAMPATH-1 antigen) 1 99 211
450293 N36754 Hs 171118 hypothetical protein FU00026 1 98 1 79
417072 BE243915 Hs 81118 leukotπene A4 hydrolase 1 98 247
429073 AA446167 Hs 47385 ESTs 1 98 1 92
448133 AA723157 Hs 73769 folate receptor 1 (adult) 1 98 294
420838 AW118210 Hs 42321 ESTs 1 98 1 67
436252 AI539519 Hs 120969 Homo sapieπε cDNA FLJ11562 fiε, clone HE 1 97 210
430702 U56979 Hs 278568 H fxtor 1 (complement) 1 97 1 84
456804 AI421645 Hs 139851 caveolin 2 1 97 1 58
439195 H89360 gb yw28d08 s1 Morton Fetal Cxhlea Homo 1 97 1 93
459299 BE094291 Hs 155651 hepatxyte nuclear fxtor 3, beta 1 97 228
413836 W92003 Hs 70614 ESTs 1 97 1 80
400417 X72475 Target 1 97 1 75
427814 W28383 Hs 180900 Williams-Beuren syndrome chromosome regi 1 96 1 46
408826 AF216077 Hs 48376 Homo sapienε clone HB-2 mRNA εequence 1 96 2.18
446135 AW130288 Hs 170318 hypothetical protein FLJ10147 1 96 206
455615 BE045344 Hs 274923 ESTs, Moderately similar to unnamed prot 1 96 221
414572 AU077174 Hs 288181 cathepsin H 1 96 265
433891 AA613792 gb no97h03 s1 NCI_CGAP_Pr2 Homo εapiens 1 95 1 71
417370 T28651 Hs 82030 tryptophanyl-tRNA εynthetaεe 1 95 288
451609 AL046019 Hs 209276 ESTs 1 94 326
447131 NM 004585 Hs 17466 retinoic acid rxeptor responder (tazaro 1 94 294
430887 N66801 Hs 260287 KIAA1841 protein 1 94 1 62
414700 H63202 Hs 38163 ESTs 1 94 1 72
417874 BE616160 Hs 82829 protein tyrosine phosphataεe, non-recept 1 94 1 56
443907 AU076484 Hs 9963 TYRO protein tyrosine kmase binding pro 1 93 222
425252 AW391162 calreticulin 1 92 214
428758 AA433988 Hs 98502 CA125 antigen mucin 16 1 92 219
425810 AI923627 Hs 31903 ESTs 1 92 1 76 433618 AA602539 Hs 345494 ESTs 192 184
424517 AI539443 Hs 137447 Homo sapienε cDNA FLJ12169 fis, clone MA 192 227
418036 Z37976 Hs 83337 latent transforming growth factor beta b 192 176
450747 AI064821 Hs 318535 ESTs, Highly similar to 1818357A EWS gen 192 172
409745 AA077391 gb 7B14E12 Chromosome 7 Fetal Brain cDNA 191 183
426780 BE242284 Hs 172199 adenylate cyclase 7 191 167
452386 R12499 Hs 20468 ESTs 191 264
438670 AI275803 Hs 123428 ESTs 191 312
414359 M62194 Hs 75929 cadhenn 11 , type 2, OB cadhenn (osteob 191 182
446566 H95741 Hs 17914 membrane spanning 4-domaιns, subfamily A 190 206
424528 AW073971 Hs 238954 ESTs, Weakly similar to KIAA1204 protein 190 185
444745 AF117754 Hs 11861 thyroid hormone receptor-associated prot 190 165
428166 AA423849 Hs 79530 M5-14 protein 190 170
426721 AA383588 Hs 131816 ESTs, Weakly similar to T29012 hypotheti 189 322
449271 AW338067 Hs 7869 Homo sapiens cDNA FLJ 11946 fis, clone HE 188 207
436576 AI458213 Hs 77542 ESTs 188 225
437751 AA767373 ESTs, Moderately similar to ALULHUMAN A 188 241
449618 AI076459 Hs 15978 KIAA1272 protein 188 163
430634 AI860651 Hs 26685 calcyphosine 188 301
440663 AW452976 Hε 247112 hypothetical protein FLJ10902 188 165
440099 AL080058 Hs 6909 DKFZP564G202 protein 188 178
414662 AL036058 Hs 76807 major histxompatibility complex, class 188 237
444051 N48373 Hs 10247 activated leucocyte cell adhesion molecu 187 207
414464 AI870175 Hs 13957 ESTs 187 268
427792 M63928 Hs 180841 tumor necrosis factor receptor superfami 187 225
415801 R24219 Hs 278443 Fc fragment of IgG, low affinity lib, re 187 205
430027 AB023197 Hs 227743 KIAA0980 protein 187 170
425771 BE561776 Hs 159494 Bruton agammaglobulinemia tyrosine kmas 187 218
412443 AW951103 Hs 130767 Homo sapiens cDNA FLJ23553fis clone L 186 227
408771 AW732573 Hs 47584 potassium voltage-gated channel delayed 186 231
420361 N92054 Hs 194718 zinc finger protein 265 186 163
413869 NM 000878 Hs 75596 interieukin 2 rxeptor, beta 186 213
422241 Y00062 Hs 170121 protein tyrosine phosphatase, rxeptor t 185 177
442434 AA995787 Hs 129583 ESTs 185 215
422735 AA169685 Hs 119529 Niemann Pick disease, type C2 gene 185 277
444083 AI123195 gboo17a10x1 Soares_NSF_F8_9W_OT_PA_P S 184 173
449679 AI823951 Hs 129700 tolloid like 1 184 157
418183 NM.001772 Hs 83731 CD33 antigen (gp67) 184 202
414776 AA155598 Hs 212839 hypothetical protein FU14195, KIAA1714 184 172
414803 X03100 Hs914 Human mRNA for SB classll histocompatibi 184 247
408669 AI493591 Hs 78146 platelet/endothelial cell adheεion molec 184 229
455508 AW976165 gb EST388274 MAGE resequences, MAGN Homo 184 169
410290 AA402307 Hs 322844 hypothetical protein DKFZp564A176 183 212
426457 AW894667 Hs 22660 chimenn (chimaeπn) 1 183 159
459247 N46243 Hs 110373 ESTs, Highly similar to T42626 sxreted 183 157
417086 AA194446 ESTs, Weakly similar to S55024 nebulin, 183 145
425175 AF020202 Hs 155001 UNC13 (C elegans) like 183 218
429952 AF080158 Hs 226573 inhibitor of kappa light polypeptide gen 183 175
438596 AA829427 Hs 243081 ESTε 183 283
436486 AA742221 Hs 120633 ESTε 182 214
433365 AF026944 Hs 293797 ESTs 182 250
449943 AF104266 Hs 24212 latrophilin 182 208
426437 BE076537 Hs 169895 ubiquitin-conjugatmg enzyme E2L 6 182 237
421563 NM 006433 Hs 105806 granulysm 182 248
449161 N53431 Hs 47647 ESTs, Weakly similar to T00057 hypotheti 181 281
453107 NM.016113 Hs 279746 vanilloid rxeptor-like protein 1 181 266
418371 M13560 Hs 84298 CD74 antigen (invaπant polypeptide of m 181 250
432946 U60899 Hs 279854 mannosidase, alpha, clasε 2B, member 1 181 205
432297 AW663632 Hs 285625 Homo sapiens mRNA, cDNA DKFZp434A119 (fr 180 313
428677 AI657119 Hs 120036 troponin I, cardix 180 294
409485 S80990 Hs 252136 ficolin (collagen/fibπnogen domam-cont 180 228
423081 AF262992 Hε 123159 sperm assxiated antigen 4 180 156
425458 H89317 Hs 182889 ESTs 180 221
425390 AI092634 Hs 156114 protein tyrosine phosphatase, noπ-rxept 180 141
409208 Y00093 integnn, alpha X (antigen CD11C (p150), 180 220
430570 AI417881 Hs 292464 ESTs 180 162
439425 AF086244 Hs 114659 ESTs 180 237
408688 AI634522 Hs 152925 KIAA1268 protein 180 213
440675 AW005054 Hs 279788 ESTs, Weakly similar to KCCLHUMAN CALCI 180 180
423690 AA329648 Hs 23804 ESTs, Weakly similar to PN0099 son3 prot 179 157
406621 X57809 Hs 8997 immunoglobulin lambda Ixus 179 218
431958 X63629 Hs2877 cadhenn 3, type 1, P-cadhenn (plxenta 179 168
403421 NM.016369* Homo sapienε claudin 18 (CLDN 179 247
430423 AI190548 Hε 143479 ESTε Weakly similar to hypothetical pro 179 292
416384 AU076903 Hs 79283 selxtin P ligand 179 187
440638 AI376551 gbte64e10 1 Soares.NFL " GBC S1 Homos 178 169
422003 AA361760 Hs 296326 ESTs 178 205
412288 NM 003005 Hs 73800 selectin P (granule membrane protein 140 177 182
432987 AI864771 Hs 27954 CD86 antigen (CD28 antigen ligand 2, B7- 177 203
441602 AI655043 Hs 133456 ESTs 177 201
458194 AW383618 ESTs Moderately similar to ALU2 HUMANA 176 235
432565 AA553477 Hs 152428 ESTs 176 263
421071 AI311238 Hs 104476 ESTs, Weakly εimilar to CGHU1E collagen 175 259 408989 AW361666 Hs 49500 KIAA0746 protein 175 166
414807 AI738616 Hs 77348 hydroxyprostaglandin dehydrogenase 15-(N 175 154
403903 C5001632* gι|10645308|gb|AAG214301|AC00 175 320
421461 AW291023 ESTs, Weakly similar to A46010 X-linked 174 267
430850 BE144152 gb MR0 HT0165060200-006 e02 HT0165 Homo 174 252
424377 AF081675 Hs 146322 killer cell lectin like receptor subfami 174 215
443884 N20617 Hs 194397 leptm receptor 174 151
423057 AW961597 Hs 130816 ESTε, Moderately similar to I38022 hypot 174 163
448262 AW880830 Hs 186273 ESTs 173 257
431890 X17033 Hs 271986 integnn, alpha 2 (CD49B, alpha 2 subuni 173 187
431630 NM 002204 Hs 265829 integπn, alpha 3 (antigen CD49C, alpha 173 221
412896 AW804157 Hs 308026 major histocompalibility complex, clasε 172 237
407366 AF026942 Hε 17518 gb Homo sapiens cιg33 mRNA, partial sequ 172 216
419407 AW410377 Hε 41502 hypothetical protein FLJ21276 172 152
442117 AW664964 Hε 128899 ESTs hypothetical protein for IMAGE 447 171 155
438606 NM 014859 Hs 6336 KIAA0672 gene product 171 157
434795 BE620794 Hs4147 translxatmg chain assxiatiπg membrane 171 221
426490 NM 001621 Hs 170087 aryl hydrocarbon receptor 171 146
418307 U70867 Hs 83974 solute earner family 21 (prostaglandin 171 249
421221 AW276914 Hs 326714 Homo sapiens clone IMAGE 713177, mRNA se 171 157
423857 N48902 Hs 133481 Homo sapiens mRNA, cDNA DKFZp564O0862 (f 171 156
408393 AW015318 Hs 23165 ESTs 170 143
432409 AA806538 Hs 130732 KIAA1575 protein 170 154
440817 AI341423 Hs 288433 neurotnmin 170 217
421445 AA913059 Hs 104433 Homo sapiens, clone IMAGE 4054868, mRNA 169 254
453691 H12235 Hs 226505 ESTs 169 207
422278 AF072873 Hs 114218 frizzled (Drosophila) homolog 6 168 154
424687 J05070 Hs 151738 matrix metalloproteinase 9 (gelatmase B 168 229
434951 AF161442 Hs 191591 Homo sapiens HSPC324 mRNA, partial eds 168 224
444301 AK000136 Hs 10760 aspoπn (LRR class 1) 168 144
407775 NM 004914 Hs 38772 RAB36, member RAS oncogene family 168 203
437119 AI379921 Hs 177043 ESTs 168 421
426836 N41720 Hs 172684 vesicle-ass∞iated membrane protein 8 (e 168 228
453498 BE181412 Hs 23245 hypothetical protein FLJ 11767 168 276
428289 M26301 Hs 2253 complement component 2 167 240
404854 Target Exon 167 176
450954 AI904740 Hs 25691 receptor (calcitonin) activity modifying 167 232
410048 W76467 Hs 343874 proline oxidase homolog 167 303
407857 AI928445 Hs 92254 synaptotagmin like 2 166 151
447827 U73727 Hs 19718 protein tyrasine phosphataεe, receptor t 166 201
417193 AI922189 Hs 288390 hypothetical protein FLJ22795 166 205
421237 U25029 Hs 102761 Human glucworticoid rxeptor alpha mRNA 166 220
433350 BE563152 Hs 10362 Homo εapienε cDNA FLJ20944 fis, clone A 166 211
417451 AW007280 Hs 115537 putative dipeptidase 165 211
443791 N64458 Hs 143345 ESTs 165 211
440475 AI807671 Hs 24040 potassium channel, subfamily K, member 3 165 204
431743 AW972642 Hs 293055 ESTs 164 264
400328 X87344 transporter 2, ATP-bmding cassette, sub 164 243
451876 T63141 gb yb99a12 s1 Stratagene lung (937210) H 164 202
417321 N68722 Hε 191368 ESTs 164 253
439237 AW408158 Hs 318893 ESTs, Weakly similar to A47582 B-cell gr 164 201
418707 U97502 Hs 87497 butyrophilin, subfamily 3, member A2 163 217
432176 AW090386 Hs 112278 aπestin, beta 1 163 204
450708 AA376654 eukaryotic translation initiation fxtor 162 205
429570 BE242256 Hs 2441 KIAA0022 gene product 162 139
448406 AW772298 Hs 21103 Homo sapienε mRNA, cDNA DKFZp564B076 (fr 162 157
439971 W32474 Hs 301746 RAP2A, member of RAS oncogene family 162 144
452424 AI964028 Hs 48353 ESTs 162 253
423161 AL049227 Hs 124776 downstream of cadhenn 6 (by 33kb) 162 138
416316 H58721 Hs 271628 ESTε 162 139
431806 AF186114 Hs 270737 tumor nxrosis factor (ligand) superfami 162 267
452203 X57522 transporter 1, ATP-bmding caεεette, sub 162 245
427509 M62505 Hs2161 complement component 5 rxeptor 1 (C5a I 162 151
438089 W05391 nuclear receptor subfamily 1, group I, m 161 145
409038 T97490 Hs 50002 small inducible cytokine subfamily A (Cy 161 152
433417 AA587773 Hs8859 Homo sapiens, Similar to RIKEN cDNA 5830 161 240
444009 AI380792 Hs 135104 ESTs 160 215
436057 AJ004832 Hs5038 neuropathy target esterase 160 260
437352 AL353957 Hε 284181 hypothetical protein DKFZp434P0531 160 257
433614 W07475 Hs 277101 cytxhrome c oxidase subunit IV isofoπn 160 330
410494 M36564 Hs 64016 protein S (alpha) 159 142
411125 AA151647 Hs 68877 cytochrome b-245 alpha polypeptide 159 202
446616 R65964 Hs 334873 ESTs, Weakly similar to ALU8.HUMAN ALU S 159 252
419918 X80700 Hs 93728 pre-B-cell leukemia transcnption factor 159 204
428141 D50402 Hs 182611 solute carrier family 11 (proton-coupled 159 198
434308 N51517 Hs 47282 ESTs 158 229
447341 AF106941 Hε 18142 arrestin, beta 2 158 209
454315 AW373564 Hs 251928 BANP homolog, SMAR1 homolog 158 210
423281 AJ271684 Hs 126355 C-type (calcium dependent, carbohydrate- 157 175
433671 AW138797 Hs 132906 19A24 protein 157 205
412869 AA290712 Hs 82407 CXC chemokine ligand 16 157 271
436906 H95990 Hs 181244 major histocompalibility complex class 157 224
417771 AA804698 Hs 82547 retinoic xid rxeptor reεponder (tazaro 157 143 406825 AI982529 Hs 84298 CD74 antigen (invariant polypeptide of m 157 237
406868 AA505445 Hs 300697 immunoglobulin heavy constant gamma 3 (G 156 161
423329 AF054910 Hs 127111 tektin 2 (testicular) 156 251
424909 S78187 Hs 153752 cell division cycle 25B 155 200
431921 N46466 Hs 58879 ESTs 154 304
437400 AB011542 Hs 5599 EGF-like-domam multiple 5 154 144
426274 D38122 Hs 2007 tumor necroεiε factor (ligand) superfami 154 304
415078 AA311223 Hs 283091 found in inflammatory zone 3 153 261
417929 R27219 Hs 74647 Human T-cell rxeptor active alpha-chain 153 218
401854 Target Exon 153 208
406850 AI624300 Hs 172928 collagen, type I, alpha 1 152 152
433815 AI696602 Hs 112757 ESTs 152 257
431130 NM 006103 Hs 2719 HE4, epididymis εpxific, whey-xidic pr 152 136
453870 AW385001 Hs 8042 Homo sapiens cDNA FLJ23173 fis, clone L 151 143
414763 U97276 Hs 77266 quiescin Q6 150 207
428281 AA194554 Hs 183434 ATPase, H transporting, lysosomal (vxuo 150 146
412870 N22788 Hs 82407 CXC chemokine ligand 16 150 283
407601 AC002300 Hs 37129 sodium channel, nonvoltage gated 1, beta 150 204
432894 AW167668 Hs 279772 brain specific protein 150 225
457941 AI004525 Hs 14587 ESTε, Weakly similar to AF1518591 CGI-1 149 222
442743 AI801351 Hs 302110 ESTs, Weakly similar to MUC2_HUMAN MUCIN 149 209
419542 AA366037 Hs 90911 solute earner family 16 (moπocarboxylic 1 9 240
433124 U51712 Hs 13775 hypothetical protein SMAP31 149 139
422487 AJ010901 Hs 198267 mucin 4, tracheobronchial 149 139
429610 AB024937 Hs 211092 LUNX protein, PLUNC (palate lung and nas 148 176
417433 BE270266 Hs 82128 5T4 oncofetal trophoblast glycoprotein 148 141
429109 AL008637 Hs 196352 neutrophil cytosolic factor 4 (40kD) 1 8 144
409361 NM 005982 Hs 54416 sine oculis homeobox (Drosophila) homolo 147 131
427872 AA835058 Human DNA sequence from clone RP1-261G23 147 250
449853 AF006823 Hs 24040 potassium channel, subfamily K, member 3 147 221
431369 BE184455 Hs 251754 sxretory leukxyte protease inhibitor ( 147 150
415149 X12451 Hs 78056 cathepsin L 146 184
447217 BE465754 Hs 17778 neuropilm 2 146 140
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph 146 216
445672 AI907438 Hs 282862 ESTs 146 201
432210 AI567421 Hs 273330 Homo sapiens, clone IMAGE 3544662, mRNA, 146 210
458208 AI380016 ESTs, Weakly similar to T4S4.HUMAN TRANS 146 160
452518 AA280722 Hs 24758 ESTs, Weakly similar to I38022 hypotheti 145 140
419577 L36531 Hs 91296 integnn, alpha 8 145 140
439620 AA838727 Hε 124405 ESTε, Weakly similar to A46010 X linked 145 157
423804 AW403448 Hs 16725 interferon-stimulated transcription fact 145 210
424658 NM.002406 Hs 151513 mannosyl (a!pha-1,3-)-glycoproteιn beta- 144 200
428494 AA233439 Hs 184634 hypothetical protein FLJ20005 144 145
431573 AW971070 Hs 291160 ESTs, Weakly similar to ALULHUMAN ALU S 144 140
409524 AW402151 Hs 54673 tumor necrosis factor (ligand) superfami 143 201
406787 AW090702 Hs 240615 tubulin alpha 1 142 186
419452 U33635 Hs 90572 PTK7 protein tyrosine kinase 7 142 195
406422 Target Exon 141 202
421341 AJ243212 deleted in malignant brain tumors 1 141 147
421195 BE464560 Hs 133017 ESTs 141 242
425998 AU076629 Hs 165950 fibroblast growth fxtor rxeptor 4 141 205
426125 X87241 Hs 166994 FAT tumor suppressor (Drosophila) homolo 141 134
451220 AF124251 Hs 26054 novel SH2-contaιnιng protein 3 140 210
409238 AL049990 Hs 51515 Homo sapiens mRNA, cDNA DKFZp564G112 (fr 140 364
411880 AW872477 gb hm30103 x1 NCI_CGAP_Thy4 Homo sapiens 140 324
432133 AB033088 Hs 272567 KIAA1262 protein 140 278
428833 AI928355 ESTs 140 202
455797 BE091833 gb IL2 BT0731-260400-076-F04 BT0731 Homo 139 155
415765 NM.005424 Hs 78824 tyrosine k ase with immunoglobulin and 139 209
427732 NM 002980 Hs 2199 εxretin rxeptor 138 244
449746 AI668594 Hs 176588 ESTs, Weakly similar to CP4Y HUMAN CYTOC 138 185
407568 AA740964 Hs 62699 ESTs 138 313
422573 AW297985 Hs 295726 integπn, alpha V(vιtronxtιn rxeptor 138 138
427138 N77624 Hs 173717 phosphatidic xid phosphatase type 2B 137 112
457918 AL359590 Hs 162604 hypothetical protein DKFZp762M186 136 201
423696 Z92546 Hs 131819 Sushi domain (SCR repeat) containing 136 254
416700 AW498958 Hs 343475 cathepsin D (lysosomal aspartyl protease 136 204
407244 M10014 fibπnogen, gamma polypeptide 136 129
451109 F11875 Hs5534 Homo sapiens cDNAFLJ12961fis, clone NT 135 134
406654 M90686 Hε 73885 HLA-G histxompatibility antigen, class 135 247
407603 AW955705 Hs 62604 Homo sapiens, clone IMAGE 4299322, mRNA, 134 166
445417 AK001058 Hs 12680 a disintegππ-like and metalloproteaεe w 134 192
436982 AB018305 Hs 5378 εpondin 1, (f-εpondin) extrxellular mat 134 186
427507 AF240467 Hs 179152 toll-like rxeptor 7 134 211
446967 AI699629 Hs 156781 ESTε 134 375
436553 AW407157 Hs 8997 immunoglobulin lambda Ixuε 134 218
456637 AW161450 Hs 109201 CGI 86 protein 133 178
422129 AU076635 Hs 1478 εeπne (or cyεteine) proteinase inhibito 133 195
417785 X59812 Hs 82568 cytxhrome P450, subfamily XXVIIA (stero 132 205
414849 AW372721 Hs 291623 ESTε, Weakly similar to unnamed protein 132 208
436986 AA740983 Hs 210792 ESTs, Weakly similar to ALU8.HUMAN ALU S 132 206
410598 AI817130 Hs 9195 Homo sapiens cDNA FLJ13698 fis, clone PL 132 208
424247 X14008 Hs 234734 lysozyme (renal amyloidosis) 131 129 428500 X78565 Hs 289114 hexabrachion (tenascm C, cytotxtin) 130 125
413474 T86312 Hs 334485 Homo sapiens cDNA FLJ14438 fis, clone HE 130 192
406659 AA663985 Hs 277477 major histxompatibility complex, class 130 222
451049 AA013353 gb ze28h10 s1 Soareε retina N2b4HR Homo 130 212
436494 AA720997 Hs 128295 ESTε 129 230
438374 AA321866 Hs6193 hypothetical protein FLJ 14590 128 234
417801 AA417383 Hε 82582 integnn, beta like 1 (with EGF like rep 128 239
425883 AL137708 Hε 161031 Homo sapiens mRNA, cDNA DKFZp434K0322 (f 128 169
428458 AA428820 Hε 251399 neurogran (protein kinase C substrate, 127 200
443180 R15875 Hs 258576 claudin 12 126 125
421764 AI681535 Hs 148135 seπne/threonine kinase 33 126 201
414217 AI309298 Hs 279898 Homo sapiens cDNA FLJ23165 fϊs clone L 126 121
433283 BE041135 Hs 175622 ESTs 124 305
426759 AI590401 Hs 21213 ESTs 123 120
436446 AW016809 Hs 119021 ESTs 123 120
421467 AA291590 Hs 97252 ESTs 122 154
431353 AA828032 ESTs 122 300
427403 AA402107 Hs 257146 ESTs, Moderately similar to I38022 hypot 122 191
453037 AA045175 Hs 17914 ESTs 122 240
437608 AA761605 Hs 292308 ESTs, Weakly similar to ALULHUMAN ALU S 122 226
439941 AI392640 Hs 18272 ammo acid transporter system A1 122 122
451385 AA017656 gb ze39h01 rl Soares retina N2b4HR Homo 121 149
400496 ENSP00000224716* GTP-bmding protein SAR 120 125
409432 D49372 Hs 54460 small inducible cytokine subfamily A (Cy 120 144
407239 AA076350 Hs 67846 leukxyte immunoglobulin like rxeptor, 119 206
426486 BE178285 Hs 170056 Homo sapiens mRNA, cDNA DKFZp586B0220 (f 118 202
445033 AV652402 Hs 72901 cyclm-dependent kinase inhibitor 2B (p1 117 114
439866 AA280717 Hs 6727 Ras-GTPase activating protein SH3 domain 114 116
440555 D31292 Hs 6853 hypothetical protein FLJ22167 114 219
446006 NM_004403 Hs 13530 deafnesε, autosomal dominant 5 113 112
432203 AA305746 Hs49 macrophage scavenger rxeptor 1 112 243
432798 AA565309 Hs 194015 ESTs 110 223
411274 NM 002776 Hs 69423 kallikrein 10 110 109
438856 N40027 Hs 7473 ESTs 109 152
421552 AF026692 Hs 105700 secreted frizzled related protein 4 109 107
448253 H25899 Hs 201591 ESTs 108 210
409718 D86640 Hs 56045 src homology three (SH3) and cysteine π 108 208
409798 AA248587 Hs 30237 ESTs, Weakly similar to ALUB HUMAN "" 106 158
449321 AA001150 Hs 132937 ESTs 106 206
418693 AI750878 Hs 87409 thrombospondm 1 106 102
402333 Target Exon 103 103
421814 L12350 Hs 108623 thrombospondm 2 102 102
425664 AJ006276 Hs 159003 transient rxeptor potential channel 6 100 236
458158 AW296778 Hs 144734 Human DNA sequence from clone RP3-416F21 100 273
406517 nel (chicken) like 2 100 207
442526 AW277221 ESTs 100 221
446164 AW273539 hypothetical protein FLJ23577 100 252
449122 AI631310 Hs 196955 ESTs 100 223
438038 AI732629 ESTs, Weakly similar to TA2R HUMAN, BETA 100 204
429420 AK001679 Hs 202289 hypothetical protein DKFZp434P1735 100 202
453672 U73531 Hs 34526 G protein-coupled rxeptor 100 257
436187 AK000998 Hs 297221 Homo sapiens cDNA FLJ10136 fis, clone HE 100 264
438909 AF085839 gb Homo sapiens full length insert cDNA 100 223
423609 AA328348 Hs 218289 ESTs 100 219
419261 X07876 Hs 89791 wingless-type MMTV integration site fami 100 228
436284 AA708016 Hs 190389 ESTs 100 222
440932 AI801509 Hs 182080 ESTε 100 166
403420 Target Exon 100 186
431169 AW971240 gb EST383329 MAGE resequences, MAGL Homo 100 202
425916 NM.006786 Hs 162200 urotensm 2 100 211
419721 NM 001650 aquapoπn 4 100 226
421761 AL120297 Hs 108043 Fπend leukemia virus integration 1 100 186
425781 AF001622 Hs 159523 class-l MHC-restπcted Tcell assxiated 100 196
415094 D59513 Hs 330778 ESTs 100 232
434088 AF116677 Hε 249270 hypothetical protein PR01966 100 226
420727 H75701 Hs 99886 complement component 4-bιndιπg protein, 100 184
430049 AW277085 Hs 99619 ESTs 100 187
446868 AV660737 ESTs 100 179
418786 AI796317 Hs 203594 Homo sapiens uncharxteπzed gastπo pro 100 144
436391 AJ227892 Hs 146274 ESTε 100 130
413059 BE151498 gb RC0-HT0295-291199-031-E11 HT0295 Homo 100 142
427739 AW196755 Hs 98105 NYD-SP14 pratem 100 241
452788 AW294571 Hs 136040 ESTε 100 223
TABLE 32B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank xceεεion numbers
Pkey CAT Number Accession
431089 125941.2 BG940189AW063489AA715980BF001091 BF880066AA666102AA621946 AA491826 421798 3042.4 BC017829 AW276646 AI984209 AA663933 AA634104 AA551528 AA634041 AA298038 BG483990 T89297 BF853958 H64685 T90329 T60644
T57747 BF852694 T92529 BG482852 BF883064 BF883066 N74880 AA829796 N90716 400269 2726.1 X65018 BC022318 NM.003019 BE465060 AI732255 BF446634 AI820677 AI002217 AI924488 BI821373 BI770406 BI823937 BI820265 BI489632
BG482911 AA617783 AI807697 AW205576 T94427 AA487101 T94513 BI819407 BI822450 BI820618 BI824619 BG542824 BG537862
432222 539529J BG207209 BE166299 AI204995 BG199355 AW969908 AA528756 AW440776 BI044354 432810 101919.1 BG292389 C06094 AI668930 AW104534 AA310513 AA830127 AW134897 AA046953 AW965490 AI810530 BF092924 AA334151 AA334725
D31302 R20723 AA263003 BI824635 AI276287 AI684428 AI524234 AI335035 AW014704 AI911443 AA972102 AI367512 AI126670 AW016017
AI286003 AI147163 AA626033 AI539156 AA565542 AI094253 AW512612 BE889628 AA744752 BE646306 AW471324 AA999975 AA863400
H17550 AI991439 R46187 BE929954 AA333976 D63102 BF744491
418259 133853 1 BM310925 AA426110 BM310629 BF434286 AW015091 BF475996 AW118867 BE675186 AI688568 AI453594 AW590589 AI652425 AI827969
BF056946 AI802866 AI393380 AI476224 AW590639 AW136271 AI458252 AI524726 AA843768 AA782158 AI336058 AI097532 AW451563
AA459408 AA459633 AA418444 W23607 BG940150 AI493445 AW054729 AI221929 AI868744 AA215405 AA766713 AA621546 BF928317
BE464132 AI990909 AW271459 AI262061 AA215404 N74332 BG940151 BG952261 AA972115 W96315 AA689586 R69057 BF766886 BE769254
W05240
429228 215430 1 BG676155 BM009591 A1479075 AI025794 AI017967 AA448270 BE466812 AA853422 AI392649 BG952034 AA513384 BF840124 BE714620
AW969605 AI553633
459702 5395291 BG207209 BE166299 AI204995 BG199355 AW969908 AA528756 AW440776 BI044354
422667 224778.1 AI758223 AW469334 BF940841 AW080348 AI270363 AI055892 BE464168 BF431797 BE350144 BF448739 AI693409 BF432999 D62848 AA398070
AI383375 AW611490
456034 6855861 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
430709 1234627.1 AW969880 AA484613 AA501874 R34356
450726 6665201 AI732287 AW204600 T95017
442048 7504221 AW340495 AI984319 AA974603
406685 00 M18728
440028 5987301 AW473675 AI190744 W69997 AW104913 AI221098 W69996 AA885487 AA861491
437866 34267.1 U52054AL581000AA156850AW293839 BI335865AA024963 BF149420 BE073977AW602574 BE164012 BE163992 BE163974AW402161
BM194134 AW966609 W84374 BF916380 AA385173 W84366 AA383743 BF903598 AA043776 W84421 AA778446 AW444904 BF446960
AA837481 AV755538 AW468444 AW468002 AA811830 AA581806 AI866686 AI572124 AA687333 D20160 AA812489 AU185248 AU186004
AA156781 AI536733 BM144850 AI471883 AA040926 BF507639 AA043777 AW874142 BE832523 BE163972 BI022546 B1021204
458332 11396851 AI000341 AI766341 AW873274
407192 22002021 AA602964 AA609200
449328 30307261 AI884781 AI652306 AI651694 AI638744 AI962493
432340 16199801 AA534222AA632632T81234
434194 626801 AF119847 AA437261 AA436987 AH 32965
436198 287271 AK001125 AU120581 AU146612 AW301393
440248 26169081 AA876138 AI239602 AI698953
442006 12390461 AW975183 AA973583 AI365103 AI699495 AI301787
438177 933712 AK024965 AU158033 AA978370 R79120 BE327015 AA779740 R79121
435154 1266051 AW972063 AA668764 AA804491 AW665688 AA765069
423387 2612.2 L13288 AA928785 AI608912 AW872978 AA565655 AI022915 AI304920 AI564366 AI668793 AI094557 T60038 R72302 H45409 AA508805 R46356 AA418798 BM129553 BM129126 BM129292 BM128865 AI808418 AI689932 AI806573 BF431808 AW872985 AW166269 H73241 T16182 AI264547
R73391 R72085 R72840 T83751 X75299 BF754348 R94105 AW449839 R73300 NM.004624 AI797007 BE045543 BF110021 BF754250 T83923
AW884084 AA903896 AA418962 L20295 R72351 H45098 AA961010 R73210 R46451 AW884085 BI022902 BI763932 BI910138
443547 137089.2 AV645808 AA701657 AW271273 AI796734 AI472316 AI017531 AI061178 BF109096 AA548964 N83805 AA131648 AA156589 BE708349
AW952494 D30877 AV684717 Z24837 F00167 BF576150 T63841 R78995 N87474
444314 10279841 AW749625 AW749626 AW749644 AI140497
443951 MH1768.18 AI334106 R63583 AI028079 Al 140098 AI911625 AI890637 F34815 T65959 N40935 W52768 AA854747 AA861945 AA878472 AA778270 W32249
AA026061 W52662 W15352 W79670 W95384 T94283 AA002155 R82052 BE825493 BE825520
432639 12378871 AW973785 H60163 AA557608
438698 5988281 AW975851 AI911033 AI540093 AA932284 AW297855 AA829228 AA814442 AW105017
413638 15254061 H71252 BE154642 BE154668
436772 12394641 AA156151 Z25109 C05177AW975688 AA731063 N67084
448782 349801 AB018301 AL050295 BF513128 AW385080 AL551708 AI352542 AI829703 AI819388 AW629019 AW073189 AW273857 AW118768 AI453845
AI452494 AA886341 AI057144 AA904647 AI423547 AW263913 AI094774 AI434419 AI039546 AI002491 AI240412 Z25099 AA995178 AW050649
AW026140 AI796309 AI584012 BE166666 AI767991 AI309041 AA724059 AI695284 AI245095 T63971 Z40627 BE166681 BG570071 BF921915
BI562702 BG506502 AV658066 R48378 AA121543 AI096938 AA618131 H40993 R48277 AI352281 BG540263 BG538901 N95226 AI356752
AI221152Z28777 R16574 AW966449 AA044116 AW797518 BI010405 AA044288 AI093508 BE140169 T64039 BG433106 AW130367 AW130361
N73937 AA127680 AW044037 AI096437 AA384077 BF941499 T93764 BG003285
438507 2729_4 BG698329 AI417878 AI080171 AI190332 AI092344 AI357100 AA744522 AA412653 AA977007 BF438628 AA743264 AA365279 AW073197
BI493198 AA169355 BI493197 AI283051 BF436642 AA809052 AI833263
415688 1235745 1 AW971218 AA493942 AA166963 431300 1529181 1 BE159863 AA502346 AU186097 R86267 H71358 418262 5824_2 AK055180 AA490810 AI420925 AI473832 AA127397 AA127409 AW820078 AI214567 AA876961 AA283985 AI904240 D20426 BC015835 N28408
Z42826 AI927925 AW590850 AW195543 AI675823 W84675 AA767204 AW207335 AI051690 AI434786 AI051699 AW139875 BF195790 AI250256
AI767042 AI521899 AA829382 AA526451 AI971192 R08173 N20059 AA215409 Z38968 H13200 H01182 R82482 AW972928 BF242637 H01273
H13567 R82532
452194 90339.1 AI694413 AW994700 AI912946 N73548 AI082035 AW271652 W24189 W24182 AI719718 AA024658 AW810120 AW015394 T79755 AA988043
AI709339
446354 8314481 AI701583 A1291038 AW449650
406687 00 M31126
411605 10026.3 BG256892 H10532 N46614 R52610 AW977696 BM460488 W56819 BI042183 BG977498 BE767451 BF870009 BG477472 R61137 R14274 R20259
R09686 BI838226 BF034269 AA429173 BE741829 AW867495 AI123683 AW006831 BE831162 AW452753 AV742717 W86152 BF115102 AI633815
BF921562 AA094230 BE092587 W86151 AA526153 AI672156 BF914496 R12579 BF852352 AA699780 T57386 BF903022 R09933 AA678288
428713 21322.7 AA432067 AW572442
414221 6855861 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
414991 17851361 D78831 C17898 D78863
447197 21768051 R36075 R36167 AI366546
430915 1978441 BG425760 BF997600 N48516 W73454 BF816344 BF997601 AA488953
424450 16741 NM 023036 AJ295276 AF250288 AL137526 AW517074 AI870459 AI215420
409031 9531 1 BF036043 AW190446 BG194731 AW662036 AI445021 BE937550 AW818972 AW393132 AA834685 BF112058 AV721682 H16423 AI270167
AI857345 AA937302AW818444 BE929780 BG498678 BF155010 BI598271 BI599811 BE161728 AW578737 AW753711 AW379707AW381918
BG506608 AW028637 AW994240 BF887392 BF790073 AW381624 AV727105 BF439618 AA443174 AI018009 N42850 AW573242 AI417258 AA463483 AI676131 Al 167170 AA836627 AA443828 AW592922 AA235129 AA730278 AW439062 AW474332 BI043239 AW474342 BG708553
AW362423 BF090028 BE827256 R16550 R39478 R39479 R94368 BG540916 BM314745 AA251087 D54231 D55274 BF085805 D31589 AW966405
AW994425 D81879 BE093545 AW901107 AA383529 BI021552 R56420 N39976 AA573281 H82595 AA234955 BE093539 AW367006 BF358697
BF366318 AA663856 BE702099 BF035969 AI267384 AI267232 BE348320 AA621574 AA861212 BF083343 BF083341 AV745131 D53074
AW954476 AW954472 AA376836 AV724531 D53063 C14928 AA093287 AA062638 BG483558 BE940050 AA765954 T70171 BE938775 BE940057
D53502 AW373300 AL118798 BM128728 AA193411 AW444709 AW952455 AI887612 BF431948 BI496876 AI264159 BM128481 AI624657
AI689301 AI969467 AA861685 AA251595 AA625761 AA872090 AI826790 AA328366 BE827416 R75951 D56918 R68122 BE827384 AL118797
AI184164 AA164411 BI495332 BE858113 AI863860 H00660 T69849 AW780389 C14667 BE934995 BI018652 R92801 AA164410 H00752
AW373305 AW373299 AW373302
418304 10932091 BE883520 BI057842 AA215702 AA215703 AA368006 BE006876 BE066555
449677 795051 AA002232 T99209 AA002071
437838 2512601 1 AI308202 AI307229 AA769348
429421 117617 T AW341668AI201382 AW104364 AA648367AA897604 AW977914 AA811957 AI352198 AL040620
410730 1146391 BG427950 AA826016 AI903441 BG939868 AW979154 AA640872 BG547134 AA457091 AW368860 W88852 R94779 AA088823
427876 13739141 AI494291 AI582807 AA417018 AA608841
434987 1219851 AW975114 AI096634 AI767001 AA658364 AW517542
442369 26917131 AA993566 AI521958 AI565071 AI864217
408873 1053371 AL046017 AW504804 AA532433 AI634701 AI126421 AW151275 AA620782 AA933047 AI828223 AI624555 AI624489 AV749032 BI495751
AI672286 AA342944 AV748076 AV747586 AA058597 H56073 W87367 R71630 H84499 AI866297 D25918 AV746788 N78995 H63752 H82985
R46600 BE786692 R71128 AA608909 R29728 BG534018
400277 170 1 Y00281 NM.002950 BC010839 BC007995 BG675232 BM468552 AL555484 BG831516 BF035300 BG677277 BF852972 BE314901 BF850656
AI371816 AA292474 AA375747 AA308414 BM454544 BI333370 BM049921 BI461428 BI465007 BI223401 BE856245 AW821164 BF914775
BF914761 AU125835 BI222678 BI091137 BF340536 BM462798 BI224452 BG707915 AL569160 AA443815 AW572867 AW363410 BF739268
BG010283 BI013120 BF818845 BF763468 AA305165 AI630370 AA039826 R24906 H02046T96891 BF981330 AW936510 AA478169 H04587
BG166574 BI869342 BE562482 BE539637 AA165089 AL579118 AL553699 BE044054 AW117440 AI520674 BF435417 AW245648 AI952404
T29534 AU153459 AU152168 AW591591 AU146918 AI393187 AA478013 AU148143 AI224471 AI640728 AI871537 AW264752 N93787 AI189357
AV756134 AI471659 AU147466 AA779206 AU149419 AU149104 AU159135 AA312221 AW445119 AW021912 AI799771 F04407 AI285530
AI914643 AW068751 AA513325 AA164627 AA639285 AA569644 T96892 AI923594 BF439180 BI770936 BF032438 AU154884 AA682793
AW072992AU158815 A1884444 AL048031 AU158922 AU152546 AI695187 AL048033 AI245650 AU148507 AW467451 BE536868 BF913001
BF062707 AL573082 AW067993 AA523354 BE886727 AI890705 AU159092 AI982693 A1817553 AA236729 AI687858 BG163767 AI524675
AI678155 AA127100 AI762661 AU159718 AI469720 AA483627 AW131696 R26868 AH 99885 AW875614 AW938694 AW578974 BI763988
BG819168 BE874767 BG978292 BE162948 AL555483 AW189718 T56783 A1018819 AI476552 BI492837 AI824440 BG996262 AA932887 AI380726
R79530 AA622108 AI262575 T56782 R27437 BE784153 AW129549 AI675567 AI866759 BG987935
432212 629625 1 AW972351 AW182936 AI478370 AA528309 BG997292 AW137742 AI632006 AA775020 AA961625 W86628 BF112014 AI275423 AI680786 421057 265006 1 BE222349 AA830545 BF224127 H99396 N81017 N81016 AI525205 T58283 449444 2735_1 U59185 NM 004696 AV734324 AI245349 AA369517 H88760 D79128 AA970406 H01059 H88761 H03446 BG620383 AU135008 AU136895
AU158158 AU155762 R73608 R65751 23756 N74630 AW078687 BE439761 BE786351 68994 BE785867AW297502AW297553 BG431545
AW814843 BF382644 BG429539 BE929862 BF811258
424831 1272834 1 H61453 AA838765 AI693104 AA721107 434542 11990.1 AF392454 AK023074 AI884890 AI814455 AW966220 BF736545 AA026021 AA286843 AA251918 BG197710 AA026294 AA337356 BC010422
AK023226 NM 022776 BM459496 AA769310 AI826460 AU153650 AU160375 AW166211 AW292992 BF433538 AI823888 AI684798 AI655985
AW770982 AI400454 AI276257 AA639510 AI689818 AW772604 AA807639 AU130298 AU132028 BF900889 BF904822 AY007102 AU143256
BG621460 AA829630 AI864665 AI084922 AA025234 AI360060 AA766554 AA026295 AA825817 AA251762 BE180751 BM464530 AV715833
AA779447 AI452519 AW418525 AA435643 D25894 AA435651 AA286844 N64369 AI702262 BG288063 BE170545 BM466232 BE299160 AA169573
AL567428 BF217285 BE967276
406851 0.0 AA609784 R97304 414936 1782849.1 C14774 C17911 D79033 430015 713.2 BC017171 BC012195 NM 007126 AF100752 AL137377 Z70768 BM474865 BG754806 AU124376 BG757203 BG764420 BG775028 BG824418
BM045810 AU120387 BG770238 BG686740 BG913323 BI759980 BG395998 BM048875 BE881070 BE313689 BE879144 BM309834 AW245847
AI770171 BF196861 BE856897 AA463876 AI375927 AA648810 AA948193 AA490916 AI459893 AI458188 AI240408 A1191843 AI131029 AW768399
A1365196 AW337984 AW026150 BE466591 BE674599 AI818438 AA772197 AI651927 AW151143 BI198825 BG819083 BM458764 BE903567
BE732715 BM043200 BE900263 BE900706 BE731097 BE390023 BG875384 BF995406 BF988930 BM475542 AW246215 BE501897 BE903610
BE561530 BE560537 BE903782 BE732947 BI227204 BG761305 BE262642 BE391848 BE382475 BG008258 BI547991 BI459099 BE391391
BE259420 BE298108 AW245422 AI423847 AI914618 H80534 BE301004 AL531791 AI435581 BF793112 AL577303 AA373265 BE746965 BF743630
BE879296 AI359493 BM018598 AI689260 AW072450 F20201 AW151405 AW517572 AA773468 BG259694 BE391163 BG621529 AI421728
BG767231 BM462953 BG340524 W52648 AA113434 BE785431 BI041981 BG832385 BG253168 BG759470 BF369329 BF981332 BE259418
BE785738 BI091658 N72512 W58732 W85690 BG958889 AI205206 H19721 W17051 W77958 BI262010 AA844319 W74143 W72214 N85194
BE734033 BG164099 AA931069 F13645 R41394 AK025758 BG180977 BE349455 AA812018 AA740241 AI027722 AI150356 AA886395 AW977627
BE220225 AA884082 AW518114 AI243844 AA809493 AA481029 AA825718 AI347866 AI431670 AA814436 AI251109 R07704 AA765606 AA724593
AI918399 AI537550 AA491103 AW008188 R07703AA989120 AA746235 AW028983 AA789102AU185751 AW971465AA489681 AW971893
AW612086 BE077936 BI860809 BE002760 BG746251 BE962912 BM454584 AL134894 BF104082 H80591
431843 445334.1 AW970134 AA516420 AA543007 BG057526 BI001430 AI498371 D60181 D81004 D60382 C15876 N91070 C14815 C15068 D80763 C14818
C15161 D60184 D60656
414516 60847.1 AK057782 AI146454 BG703115 AI765980 AI948611 AA889263 AA947457 BG547193 H11947 Z38147 F10426 BF447329 H11946 T74968 F06195
BG548563 AI004988 AA148735 AI307802 AI439791 BE041453 AI984904 AA148734 F12823
459557 8597941 BG623239 N58315 AI524952
437204 28243.1 AL110216 AI816283 AI688476 AA928351 AW157672 AI288740 BE468242 AI452476 AI291665 AW192364 BE503635 AW592672 AA857393
AW162770 AI680660 AI879565 AI347717 BF880800 AI266646 AA834381 AI291667 AI264567 Z38449 T03352 AI929432 BE673697 AI124770
AI350389 AA910378 R54042 AV746670 AW089037 AV729218 H28971 R38549 AI692560 BE671562 BE669916 BE672206 BF445152 BF445151
AI914323 AI684406 AA932348 BE670597 AA932080
439195 219791 AF086037 H89360 H89546
433891 6472901 AW182329 AA613792 T05304 AW858385
425252 38271 1 AK056513 AL553942 AL553941 BG924307 BE879339 AA576941 BG054674 BF431361 BE467806 BF445874 BE138798 AA425029 BF084265
BE814324 BM466426 BE819467 AW594593 AA341536 AI823511 BI792998 AW296213 AW800506 AW378236 BE819553 AW341342 BE146513
BE146525 BE146515 AW295689 BE146518 BE146516 BF349828 AL520587 AW803944 BE931092 BF375188 BG676709 BF832746 BG696737
AW391179 AI582980 AW582217 AW814484 BE672215 AW391162 AW814336 AW814302 AW814444 AL520586 AI333134 AI378333 AW243412
BE350482 AI628661 AI925481 AI246159 AW593633 AI273558 AI494388 AA806280 AW005606 BE048135 AW341024 AA969419 AA912778
AA621100 AA479920 AI867584 AI290391 BE348490 BF340755 AI225038 AI867592 BG113588 AI566808 AW196841 BF087184 AA353524
AW957546 BF340833 BF037221 BE146523
409745 MH1944.5 BI030997 AA921874 AW188822 BI027862 AI347618 AI361453 AI088754 AW207491 AA077391 BG012775 BG997382 AA286833 AA150722
BI007625 BI027864 BI009100 BI006275 BI006270 BI031000 BI029864 BI006277 BI007627 BI006266 BI006991 BI006990 BI007763 BI007762
BG997377 AA150780 BI033518 BI027818 BG015789 BI033807 AA341445 437751 643238.1 AW978796 AA767373 AW173343 AA836163 N27563 AA905328 R97032 444083 10908 12 BI836699 AI123195 455508 1239880.1 AW976165 C04000 417086 1154.2 AK056605 AK056969 AW380724 AA195950 F21243 Z17422 AA176595 AA176955 AA194350 BC005933 BC017866 AA196396 Z24810 AA181361
AA193115 AA086465 F25194 F30130 AA180013 AJ346143 F20589 F20620 F29371 F32439 F25153 F32146 F26110 F28506 F25307 F27533
F20375 F32370 AA653078 BF574897 Z24852 F00172 T30560 AW449825 AI620346 BG986374 BE706521 C02691 AL596834 F31902 F26078
AA670099 BF475555 F30818 F37524 AJ346558 F28050 F17933 F31637 C03413 AI092152 AA180743 AA085730 F21998 F20854 F18944 F31180
F37937 F37738AA193162Z17344AA192546
409208 10117.2 AK074047 AI144342 AW014280 BM145128 N28267 AW206231 AA989041 H93197 AW594063 BG236296 AW236606 AW081031 AA765843
BM144372 AA989341 AI824838 AI963970 AI637671 AW196330 BG427526 BM148789 BF893644 BF881946
440638 3711651 BG009500 AI376551 AA897445 T87714
458194 5062721 AI692525 AW005307 AW383618 AI689861 AI342712 AA906899
421461 1289181 AA291529 AI629027 AI890447 AA677465 BF001179 AI301102 AW452003 AA704419 AA706883 T68871 AW291023
430850 296806.1 BE144152 AA487799 BF916865 AA937952
400328
451876 23285791 T63141 AI821021 BF370092 BF370127 BF370060T62998
450708 12745.1 AK055196 AW952031 AI694545 AI742403 AW874431 AW204731 AI887383 BE220997 AA011287 AA115112 AI306385 AW571707 BF433009
AW197042 AI367086 H23002 H11743 R37085 Z39208 AI002267 H10206 T23948 W74801 R51633 R37677 R59986 H10833 BG012000 R13817
H22794Z43122 H10257 BG984543 H10875 BG984542AA318232 BF849799W76367AA376654 R18795AA114979 AA303838AW139819
AI674165 AI686172 W94102 R67170 H11820 BG015023
452203 2630.1 BC014081 NM 000593 X57522 L21208 L21207 L21206 L21205 L21204 AL561404 AL546423 AL560492 AL556882 AL541576 AL550654 BI823519
BI770023 AL554969 BI489906 AI304693 AW295947 BM146642 X57521 BG820143 BE898390 F06770 F12630 BM423610 AL561518 BM009470
BG742981 AA279685 AA847441 AA313737 BF172639 BF897216 BF914190 BF903647 S70277 AI569694 A 073296 AI361433 AA564644
AA487429 BE858232 AA838610 AI539114 AI719375 AI829129 BG057675 AI423422 AU158860 BE300655 AW170777 AA586956 AL571889
AL556850 AL576404 AL582800 BI256544 BF342301 BG875994 AA054458 AA353161 AI940434 BE816522 AL577636 AI479650 AW150377
AU154395 AW951271 AI032220 AI819778 A1346733 AW771150 AW512525 AI249904 AA279809 AI352549 AW512517 BG056280 AA521222
BE271141 AL581932 AL541575 BI819184AV660190AL556475 AI620020AW089888AW079179Z21518AA687601 F04651 AI783961 T57198
AI433367 T78652 AL554968 AA365648 AL582619 BE874601 BF804669 AL574458 BM145502 AI266514 A1538823 AI475626 AA948210 AA884054
AA487637 AA031844 AA535221 AW794256 AW361447 BE788505 AI682892 AA830989 AA862356 AA653084 BM009154 AA135727 H05927
H23433 R42244 N79997 AW366665 AW366601 AA678742 AL556474 AA135770 BE774050 BF914200 H88457 AA627746 BI560216 BI753586
438089 22448.4 BM475665 BE644917 AW770789AW952971 64863 BM263259AI224545AI184866 N69114AW518902AI440169 AA809472AV654440
AA281642 AU185230 AW337382 AI872923 AI537113 N73882 T83378 H63731 BF671764 AW897824 AI811204 AA344646 BE009112 BG899664
H91240 R60548 N41701
427872 4983.5 BI826340 BI868674 R12615 AW887767 BF439409 AI424995 BG059893 AA417003 AI220270 AA418740 AI190974 Z39070 AA742556 AA835058
AA694436 R20520 AA418795 BG460307 BI560147
458208 45807.4 AI990640 AI380016 BM273298 BM273060
421341 1407.1 NM.007329 AF159456 AJ243212 AJ297935 AA295769 NM_017579 AJ243224 AI492875 AI796676 AI749838 AA918144 AI814590 AI923531
BF513992 AI720725 AI150879 AI279072 AW612904 AI492104 AI284510 AI141231 AA613554 AW662148 AW769047 AA565985 AW612888
AU100513 BG955585 BG955588 AA295763 BE829414 BF760645 BG954398 AA295332 AA295795 BE932867 AW769569 T89953 BE934311
411880 11390831 BE088101 T05990AW872477
428833 3177531 AI928355 AI709178 AA436447 AI431274 BF946000
455797 1511159.1 BE091833 BE091874 BE091871
407244
451049 839231 W92422AA013353
431353 12411261 AW977507 AA503803 AA767137 AA828032 AA828033
451385 850221 AA019761 AA017656 AA017374
442526 4503701 AF150283 AW182000 AW277221 AV735848
446164 416482 AK026817 AI559708 AW273539 AW892986
438038 2523501 1 AI732629 AI732831 AA776249
438909 40451 AF085839 R69254 R69137 AW188788
431169 12357601 AW971240 AA493723 AA493843
419721 408161 AK026728 AL138136 BF059437 AI657037 AL600872 C15206 C14676 AA001003 AL157562 BG706081 H24162 BF841047 H15952 Z45355
AL157565 AV721762 AW953127 AA324171 BF476417 R52508 N54211 R46734 BG485659 BF810747 BE766227 AL538364 R19964 T15657
AW197333 R16235 R40826 BG152309 AV729035 R45066 AA016969 BE504976 BF593783 N51085 R61284 BE702264 AI216994Z41068 N72577
R37645 AW237014 AW197630 AI359402 AA707906 AL119885 H23480 T16037 AI950756 T62597 T91664 R40195 D60186 H23014 T89715 H05749
H24054 AA001565 H15041 C15205 D59987 R13787 R61283 H23479 H07874 R14070 R52555 R21139 H05856 AA348655 AL120460 T62525
AV725241 AA046875 AI361912 H13341 BG150488 AL119338 Z42792 F05895 H07966 F06492 R59866 D31594 H09436 R35726 BI917845
BG704196 BF735198AL036526 BG568878AW185713 R59867AA016968 H09087 BE841173AW893631
446868 15525.1 AK074473 BC017997 BI831060 BF971101 AI886394 AI082824 AV708785 W86073 W07772 AV660737 AI816793 R52250 BG183529 AA633473
AI191256 R44763 R19947 BF571346 W86257 413059 1488711.1 BE063078 BE151503BE151498
TABLE 32C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, etal (1999) Nature 402489-495 Strand Indicates DNA strand from which exonε were predicted
NLpoεition Indicates nucleotide positions of predicted exons Pkey Ref Strand NLpoεition
400880 9931121 Plus 29235-29336,36363-36580
402474 7547175 Minus 53526-53628,55755-55920,57530-57757
406387 9256180 Plus 116229-116371,117512-117651
404277 1834458 Minus 91665-91946 402674 8077108 Minus 39290-39502
404240 5002624 Minus 116132-116407,116653-116922
405102 8076881 Minus 120922-121296
406122 9144087 Minus 30940-31386
400750 8119067 Plus 198991-199168,199316-199548 404394 3135305 Minus 37121-37205,37491-37762,4105341140,4132
403421 9665041 Minus 126609-126773,139986-140205
403903 7710671 Minus 101165-102597
404854 7143420 Plus 14260-14537 401854 7770538 Plus 151483-151637,151902-152008,152146
406422 9256411 Plus 163003-163311
400496 9743564 Plus 41515-41695
402333 8844110 Minus 165693-165856
406517 7711431 Plus 7151-7402
403420 9664969 Plus 159835-159938
TABLE 33A About 800 geneε upregulated in lung fibrosis relative to normal lung
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of lung fibrosis Als divided by 90th percentile of normal lung Als, where the minimum value for the numerator and denominator was set to 50
Pkey ExAccn UnigenelD Unigene Title R1
406964 M21305 FGENES predicted novel secreted protein 16 10
431089 BE041395 ESTs, Weakly similar to unknown protein 1238
421110 AJ250717 Hs 1355 cathepsin E 11 86
428330 L22524 Hs 2256 matnx metalloprotemase 7 (matπlysin, 11 62
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (placenta 990
444381 BE387335 Hε 283713 hypothetical protein BC014245 858
406850 AI624300 Hε 172928 collagen, type I, alpha 1 826
429500 X78565 Hs 289114 fiexabrachion {tenascm C, cytotactin) 824
422487 AJ010901 Hε 198267 mucin 4, trxheobranchial 772
408380 AF123050 Hε 44532 diubiquitin 7 24
432306 Y18207 Hs 303090 protein phosphatase 1, regulatory (inhib 15
456034 AW450978 gb Ul-H BI3-ala-a 20-UI s1 NCI_CGAP.Su 7 12
453355 AW295374 Hs 31412 myopodin 696
408562 AI436323 Hs 31141 roundabout (axon guidance rxeptor, Dros 688
421552 AF026692 Hs 105700 εecreted frizzled related protein 4 6 83
426125 X87241 Hs 166994 FAT tumor suppressor (Drosophila) homolo 672
407192 AA609200 gb af12e02 s1 Soares.testis.NHT Homo sap 672
438089 W05391 nuclear rxeptor subfamily 1, group I, m 662
449523 NM 000579 Hs 54443 chemokine (C-C motif) rxeptor 5 656
421952 AA300900 Hs 98849 dynein light chain 2B (DNLC2B) 646
417433 BE270266 Hs 82128 5T4 oncofetal trophoblast glycoprotein 632
439195 H89360 gb yw28d08 ε1 Morton Fetal Cxhlea Homo 629
444301 AK000136 Hs 10760 aspoπn (LRR class 1) 6 28
414061 NM.000699 Hs 335493 amylase, alpha 2A, pancreatic 613
423057 AW961597 Hs 130816 ESTs, Moderately similar to I38022 hypot 6 11
430702 U56979 Hs 278568 H fxtor 1 (complement) 610
424878 H57111 Hs 221132 ESTs 600
417878 U90916 Hs 82845 Homo sapiens cDNA FLJ21930 fis, clone H 600
414217 AI309298 Hs 279898 Homo sapienε cDNA FLJ23165 fiε, clone L 594
408491 AI088063 Hs 7882 ESTs 594
419407 AW410377 Hs 41502 hypothetical protein FLJ21276 592
432222 AI204995 gb an03c03 x1 Stratagene schizo brain S1 592
407857 AI928445 Hs 92254 synaptotagmin-like 2 590
433230 AW136134 Hs 220277 ESTs 586
412719 AW016610 Hs 816 ESTs 586
407788 BE514982 Hs 38991 S100 calcium binding protein A2 5 82
426759 AI590401 Hs 21213 ESTs 572
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial 572
421814 L12350 Hs 108623 thro boεpondin 2 571
430887 N66801 Hs 260287 KIAA1841 protein 570
453870 AW385001 Hs 8042 Homo sapiens cDNA FLJ23173 fis clone L 562
436954 AA740151 Hs 130425 ESTs 558
411573 AB029000 Hs 70823 KIAA1077 protein 555
432441 AW292425 Hs 163484 mtron of hepatocyte nuclear fxtor-3 al 538
410606 AW418779 Hs 114889 ESTε 538
410800 BE280421 Hs 94499 ESTε 5 32
413195 AA127382 Hs 22404 proteaεe, serine, 12 (neurotrypsin, moto 528
406687 M31126 matrix metalloproteinase 11 (stromelysin 526
417733 AL048678 Hs 82503 H εapiens mRNA for 3'UTR of unknown prot 522
412622 AW664708 Hs 171959 ESTs 522
439941 AI392640 Hs 18272 ammo xid transporter syεtem A1 5 18
440675 AW005054 Hs 279788 ESTε, Weakly similar to KCCLHUMAN CALCI 515
430299 W28673 Hs 106747 seπne carboxypeptidase 1 prxursor prot 513
425177 AF127577 Hs 155017 nuclear rxeptor interxtiπg protein 1 5 12
444314 AI140497 gb ow76b09 s1 Soares_fetal_lιver_εpleen_ 511
444527 NM 005408 Hs 11383 small inducible cytokine subfamily A (Cy 504
452239 AW379378 protein tyrosine phoεphatase, rxeptor t 497
453874 AW591783 Hs 36131 collagen, type XIV, alpha 1 (uπdulin) 496
443884 N20617 Hs 194397 leptin receptor 494
444040 AF204231 Hs 182982 golgιn-67 494
428281 AA194554 Hs 183434 ATPaεe, H transporting, lysosomal (vxuo 493
440687 AL080222 Hs 7358 hypothetical protein FLJ13110 492
420000 AB036063 Hs 94262 p53-ιπducιble ribonucleotide reductase s 492
432435 BE218886 Hs 282070 ESTs 492 422573 AW297985 Hs 295726 integnn, alpha V (vitronxtin receptor 490
430665 BE350122 Hs 157367 ESTs, Weakly similar to I78885 seπne/th 490
446006 NM.004403 Hs 13530 deafneεs, autosomal dominant 5 490
415992 C05837 Hs 145807 hypothetical protein FLJ13593 482
430027 AB023197 Hs 227743 KIAA0980 protein 478
408393 AW015318 Hs 23165 ESTs 476
449509 AA001615 Hs 84561 ESTs 472
416206 AW206248 Hs 111092 hypothetical protein FLJ22332 472
412828 AL133396 Hs 74621 pπon protein (p27-30) (Creutzfeld Jakob 472
433226 AW503733 Hs 9414 KIAA1488 protein 468
444745 AF117754 Hs 11861 thyroid hormone rxeptor-associated prot 468
442994 AI026718 Hs 16954 ESTs 466
430580 AA806105 Hs 300697 immunoglobulin heavy constant gamma 3 (G 466
409361 NM 005982 Hs 54416 sine xulis homeobox (Drosophila) homolo 466
418005 AI186220 Hs 83164 collagen, type XV, alpha 1 465
433586 T85301 gb yd78d06 s1 Soares fetal liver splxn 464
424917 AI636208 Hs 96901 hypothetical protein FLJ23049 464
424408 AI754813 Hs 146428 collagen, type V, alpha 1 464
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 462
451109 F11875 Hs 5534 Homo sapienε cDNA FLJ 12961 fis, clone NT 462
450086 AW016343 Hs 233301 ESTs 461
422163 AF027208 Hs 112360 prominin (mouse) like 1 460
442652 AI005163 Hs 201378 ESTs, Weakly similar to T12545 hypotheti 459
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of 458
418259 AA215404 ESTs 454
426716 NM.006379 Hs 171921 sema domain, immunoglobulin domain (Ig), 454
432810 AA863400 ESTs 454
407112 AA070801 Hs 51615 ESTs, Weakly similar to ALU7.HUMAN ALU S 453
436100 AA704806 Hs 143842 ESTs, Weakly similar to 2004399A chromos 452
412652 AI801777 ESTε 452
438899 AF085833 Hs 135624 ESTs 452
416179 R19015 Hs 79067 MAD (motherε against dxapeπtaplegic Dr 452
436252 AI539519 Hs 120969 Homo sapiens cDNA FLJ11562fis, clone HE 452
443324 R44013 Hs 164225 ESTs 451
407690 R47799 Hs 266957 hypothetical protein FLJ14281 451
431393 AW971493 Hs 134269 ESTs, Highly similar to cytokine rxepto 451
452518 AA280722 Hs 24758 ESTs, Weakly similar to I38022 hypotheti 450
431843 AA516420 ESTs, Weakly similar to I38022 hypotheti 450
436865 AW880358 Hs 339808 hypothetical protein FLJ10120 446
452561 AI692181 Hs 49169 KIAA1634 protein 446
440273 AI805392 Hs 325335 Homo sapiens cDNA FLJ23523 fis, clone L 445
442048 AA974603 gbop34f05 s1 Soares NFL T GBC S1 Homo s 444
436120 AI248193 Hε 119860 ESTs 444
423575 C18863 Hs 163443 intron of penostin (OSF-2os) 444
429697 AW296451 Hs 24605 ESTε 444
439866 AA280717 Hs 6727 Ras GTPaεe activating protein SH3 domain 443
429688 BE245169 Hs 211610 CUG tπplet repeat, RNA binding protein 443
414462 BE622743 Hε 301064 arfaptin 1 442
428698 AA852773 Hs 334838 KIAA1866 protein 442
420838 AW118210 Hs 42321 ESTε 441
458584 AF217518 Hs 8360 PTD012 protein 440
434340 AI193043 Hs 128685 ESTs, Weakly similar to T17226 hypotheti 440
400076 Eos Control 438
431049 AA846576 Hs 103267 hypothetical protein FLJ22548 similar to 438
445773 H73456 Hs 13299 Homo εapienε mRNA, cDNA DKFZp761 M0111 (f 436
420298 AI199510 Hs 267912 ESTε, Weakly similar to ALU7_HUMAN ALU S 436
433339 AF019226 Hs 8036 glioblastoma overexpressed 436
412490 AW803564 Hs 288850 Homo sapienε cDNA FLJ22528 fis, clone H 434
416391 AI878927 Hs 79284 mesoderm spxific transcπpt (mouεe) hom 434
421221 AW276914 Hs 326714 Homo sapiens clone IMAGE 713177, mRNA se 433
409342 AU077058 Hs 54089 BRCA1 aεεxiated RING domain 1 433
429228 AI553633 ESTε 432
426458 D83032 Hε 169984 nuclear protein 430
408369 R38438 Hε 182575 SLC15A2 Solute camerfamily 15 (H+/pep 430
432476 T94344 Hs 326263 ESTs 429
434963 AW974957 Hs 288719 Homo sapienε cDNA FLJ12142 fis, clone MA 428
436446 AW016809 Hs 119021 ESTs 427
439556 AI623752 Hs 163603 ESTs 426
428179 AI127772 Hs 279696 serum/glucxorticoid regulated kmase-li 426
428411 AW291464 Hs 10338 ESTε 426
434936 AI285970 Hs 183817 ESTε 423
413048 M93221 Hs 75182 mannose receptor, C type 1 423
432606 NM 002104 Hs 3066 granzyme K (seπne protease, granzyme 3, 422
413859 AW992356 Hs 8364 Homo sapiens pyruvate dehydrogenase kma 422
409977 AW805510 Hs 97056 hypothetical protein FLJ21634 422
441297 AW403084 Hs 7766 ubiquitin-conjugatiπg enzyme E2E 1 (homo 421
421229 AI056590 Hs 7086 hypothetical protein MGC12435 420
456844 AI264155 Hs 152981 CDP-diacylglycerol synthase (phosphatida 420
423578 AW960454 Hs 222830 ESTε 420
446608 N75217 Hs 257846 ESTε 420
424238 AA337401 Hs 137635 ESTε 419
450747 AI064821 Hs 318535 ESTε Highly similar to 1818357A EWS gen 4 18
420674 NM 000055 i Hs 1327 butyrylcholmesterase 418 428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy 418
439593 BE073597 Hs 124863 ESTs 4 17
442369 AI565071 ESTs 416
445885 AI734009 Hs 127699 KIAA1603 protein 416
459702 AI204995 gb an03c03 x1 Stratageπe schizo brain S1 416
452960 AK001335 Hs 31137 protein tyrosine phosphatase, rxeptor t 4 16
440703 AL137663 Hs 7378 Homo sapiens mRNA cDNA DKFZp434G227 (fr 415
407347 AA829847 gb od40d07 s1 NCI_CGAP_GCB1 Homo sapiens 414
409153 W03754 Hs 50813 hypothetical protein FLJ20022 4 13
430168 AW968343 Hs 145582 DKFZP434I1735 protein 4 12
451184 T87943 transcnption factor 7-lιke 2 (T-cell sp 412
426174 AA547959 Hs 115838 ESTs 4 12
431562 AI884334 Hs 11637 ESTs 412
417094 NM 006895 Hs 81182 histamiπe N methyltransferase 412
425259 AL049280 Hs 155397 Homo sapiens mRNA, cDNA DKFZp564K143 (fr 412
449437 AI702038 Hs 100057 Homo sapienε cDNA FLJ22902 fis, clone K 412
425053 AF046024 Hs 154320 ubiquitin-activating enzyme E1C (homolog 410
444020 R92962 Hs 35052 ESTs 410
439424 AI478667 Hs 118183 hypothetical protein FLJ22833 410
416987 D86957 Hs 80712 KIAA0202 protein 4 10
457121 AI743770 Hs 180513 ESTs, Weakly similar to KIAA0822 protein 409
422737 M26939 Hs 119571 collagen, type III, alpha 1 (Ehlers-Danl 409
446619 AU076643 Hs 313 εecreted phoεphoprotem 1 (oεteopontm 408
431193 AW749505 Hs 296770 KIAA1719 protein 408
452144 AA032197 Hs 102558 Homo εapienε, clone MGC 5352, mRNA, comp 408
433308 AA582718 Hs 291650 ESTs 408
445756 AA290690 Hs 300776 ESTs 408
431745 AW972448 Hs 163425 ESTs 408
444610 AI174783 gb HA2501 Human fetal liver cDNA library 407
440099 AL080058 Hs 6909 DKFZP564G202 protein 406
439398 AA284267 Hs 221504 ESTs 406
432731 R31178 Hs 287820 fibronectin 1 406
415075 L27479 Hs 77889 Fπedreich ataxia region gene X123 405
433626 AF078859 Hs 86347 hypothetical protein 405
428055 AA420564 Hs 101760 ESTs 404
412584 X54870 Hs 74085 DNA segment on chromosome 12 (unique) 24 404
413243 AA769266 Hε 193657 ESTs 402
431214 AA294921 Hs 348024 v ral simian leukemia viral oncogene hom 402
453753 BE252983 Hs 35086 ubiquitin specific protease 1 402
414504 AW069181 Hs 115175 sterile alpha motif and leucine zipper c 402
434404 AW445034 Hs 256578 ESTs 402
407604 AW191962 collagen, type VIII, alpha 2 402
429412 NM 006235 Hs 2407 POU domain, class 2, associating fxtor 402
436772 AW975688 metallothionein 1E (functional) 400
443257 AI334040 Hs 11614 HSPC065 protein 400
450187 AA736788 Hs 78521 KIAA1717 protein 398
433913 AI694106 Hs 72325 ESTs, Weakly similar to I38022 hypotheti 398
415060 AJ223810 Hs 3213 ESTs, Weakly similar to IEFS_HUMAN TRANS 3 98
434096 AW662958 Hs 75825 pleiomorphic adenoma gene-like 1 398
432374 W68815 Hs 301885 Homo εapiens cDN A FLJ 11346 fis, clone PL 398
426818 AA554827 Hs 292996 DKFZp434A0131 protein 398
440118 AB040893 Hs 6968 KIAA1460 protein 398
413836 W92003 Hs 0614 ESTs 397
442647 AL038436 Hs 31388 ESTs 396
449188 AW072939 Hs 347187 myotubulaπn related protein 1 396
450656 AA010539 Hs 18912 ESTs 386
410817 AI262789 Hs 93659 protein disulfide isomerase related prot 394
429784 M89796 Hs 30 membrane spanning 4-domaιns, εubfamily A 394
408483 AA464836 Hs 291079 ESTε, Weakly similar to T27173 hypotheti 394
407879 AA045464 Hs 6557 zinc finger protein 161 393
438146 Z36842 Hs 57548 ESTs 393
433658 L03678 Hs 156110 immunoglobulin kappa constant 393
429355 AW973253 Hs 292689 ESTs 392
437210 AA311443 Hs 293563 Homo sapiens mRNA, cDNA DKFZp586E2317 (f 392
432467 T03667 Hs 239388 Human DNA sequence from clone RP1-304B14 392
452416 AA026115 Hs 114777 ESTs 392
413873 AI310151 Hs 173524 ESTs 391
400196 Eos Control 391
437175 AW968078 Hs 87773 protein kinase, cAMP-depeπdent, catalyti 390
453204 R10799 Hs 191990 ESTs 390
454076 AW204712 Hs 61957 ESTs 390
431183 NM.006855 Hs 250696 KDEL (Lys-Asp-Glu-Leu) endoplasmic retic 390
437158 AW090198 KIAA1150 protein 390
443970 AI280341 Hs 166571 ESTs 390
441633 AW958544 Hs 112242 normal mucosa of esophaguε εpecific 1 390
452281 T93500 Hs 28792 Homo sapiens cDNA FLJ11041 fis, clone PL 390
444057 AA316896 Hs 257267 FYVE and coiled-coil domain containing 1 3 89
411495 AP000693 Hs 70359 KIAA0136 protein 388
438452 AI220911 Hs 288959 hypothetical protein FLJ20920 388
410297 AA148710 lumican 388
427698 AW972594 Hs 335499 ESTs 388
436769 AA748675 ESTs 386
417819 AI253112 Hs 133540 ESTs 386 445800 AA126419 Hs 32944 iπositol polyphosphate 4-phosphataεe, ty 386
425838 NM 014071 Hs 159613 nuclear receptor coactivator RAP250, per 386
422173 BE385828 Hs 250619 phorbolin like protein MDS019 (CEM15) 386
428147 AW629965 Hs 234983 ESTε Weakly similar to 2109260A B cell 385
445693 AW800444 Hs 76507 LPS induced TNF-alpha factor 3 85
432706 NM 013230 Hs 286124 CD24 antigen (small cell lung carcinoma 385
412636 NM 004415 desmoplakin (DPI, DPII) 384
436169 AA888311 Hs 17602 Homo sapiens cDNA FLJ12381 fis, clone MA 384
418876 AA740616 gb ny97f 11 s1 NCI.CGAP.GCB1 Homo sapiens 384
436110 AA704899 Hs 291651 ESTs, Weakly similar to I38022 hypotheti 384
430317 AB020645 Hs 239189 glutaminase 384
442806 AW294522 Hs 149991 ESTs 384
414320 U13616 Hs 75893 aπkyππ 3, node of Ranvier (ankyπn G) 382
430512 AF182294 Hs 241578 U6 snRNA associated Sm like protein LSm8 382
427051 BE178110 Hs 173374 Homo sapiens cDNA FLJ10500 fis, clone NT 382
430573 AA744550 Hs 136345 ESTε 382
453394 AW960474 Hs 40289 ESTs 381
431266 AW149321 Hs 105411 ESTs 380
434987 AW975114 ESTs 380
452685 AI634651 Hs 30250 v maf musculoapoπeurotic fibrosarcoma (a 379
435176 AA744875 Hs 189413 ESTs 378
437134 AA349944 Hs 42915 ARP2 (adm related protein 2 yeast) ho 377
430709 R34356 gb yh85d01 s1 Soares placenta Nb2HP Homo 377
427157 U51166 Hs 173824 thymine DNAglycosylase 376
441989 AA306207 Hs 286241 protein kinase, cAMP-depeπdent, regulato 376
417228 AL134324 Hs 7312 ESTs 376
418546 AA224827 gb πc32g04 ε1 NCI CGAP Pr2 Homo sapiens 376
450779 AW204145 Hε 156044 ESTs 375
412408 D51103 Hε 73851 ATP synthase, H transporting mitxhoπdr 375
443879 Z28462 Hs 9927 Homo sapiens mRNA, cDNA DKFZp564D156 (fr 375
414812 X72755 Hs 77367 monokine induced by gamma interferon 375
429494 AA769365 Hs 126058 ESTs 375
447118 AB014599 Hs 330988 Homo sapiens, Similar to Bicaudal D (Dro 375
408822 AW500715 Hs 57079 Homo sapiens cDNA FLJ13267 fis, clone OV 374
419591 AF090900 Hs 91393 Homo sapiens cDNA FLJ21887 fis, clone H 374
448121 AL045714 Hs 128653 hypothetical protein DKFZp564F013 374
436260 BE172762 Hs 292710 ESTs, Weakly similar to ALU5_HUMAN ALU S 374
421485 AA243499 Hs 104800 hypothetical protein FLJ10134 373
414883 AA926960 CDC28 protein kinase 1 372
416178 AI808527 Hs 192822 serologically defined breast cancer and 372
452250 BE618654 Hs 28607 hypothetical protein A-211C6 1 372
444099 D87432 Hs 10315 solute earner family 7 (cationic ammo 372
438607 AW080237 Hs 252884 ESTs 372
408221 AA912183 Hs 47447 ESTs 372
418699 BE539639 Hs 173030 ESTs, Weakly similar to ALU8 HUMAN ALU S 370
419900 AI469960 Hs 170698 ESTs 370
446342 BE298665 Hs 14846 Homo sapiens mRNA, cDNA DKFZp564D016 (fr 370
446100 AW967109 Hs 13804 hypothetical protein dJ4620232 370
448019 AW947164 Hs 195641 ESTs, Moderately similar to I38022 hypot 370
413283 R78669 Hs 23756 hypothetical protein similar to εwine x 370
447846 AA324057 Hs 77955 Homo εapiens cDNA FLJ23527 fis, clone L 370
436198 AK001125 Homo sapiens cDNA FLJ10263 fis, clone HE 370
418300 AI433074 Hs 86682 Homo sapiens cDNA FLJ21578 fis, clone C 369
408495 W68796 Hs 237731 ESTs 369
424452 N41367 Hs 173002 ESTs, Weakly similar to I38022 hypotheti 368
448479 H96115 Hs 21293 UDP-N-xteylglucoεamine pyrophoεphorylas 368
431974 AW972689 Hs 200934 ESTs 368
416354 NM 000633 Hs 79241 B-cell CLL/lymphoma 2 (BCL2) 368
417412 X16896 Hs 82112 interieukin 1 rxeptor, type I 368
413645 AA130992 gb zo15e02 si Stratagene colon (937204) 367
416221 BE513171 Hs 79086 mitxhoπdπal πbosomal protein L3 367
419111 AA234172 Hs 137418 ESTs 367
423979 AF229181 Hs 136644 CS box-containing WD protein 366
418875 W19971 Hs 233459 ESTs 366
451690 AW451469 Hs 209990 ESTs 366
423032 AI684746 Hs 119274 RAS p21 protein xtivator (GTPase xtiva 366
414888 AL039185 Hs 77558 thyroid hormone rxeptor mterxtor 7 366
428347 AI264161 Hε 183773 golgi autoantigen, golgin subfamily a, 4 366
426779 AA384577 Hs 93714 ESTs, Weakly similar to T00365 hypotheti 366
435335 AI693150 Hs 137928 ESTε 366
410577 X91911 Hs 64639 glioma pathogenesis-related protein 366
452933 AW391423 Hs 288555 Homo sapienε cDNA FLJ22425 fis, clone H 365
429105 D87077 Hs 196275 KIAA0240 protein 364
407813 AL120247 Hs 40109 KIAA0872 protein 364
425863 U43604 Hs 159901 Human unidentified mRNA, partial sequenc 364
451678 AA374181 Hs 26799 DKFZP564D0764 protein 364
452420 BE564871 Hs 29463 ceπtπn, EF-hand protein, 3 (CDC31 yeast 364
452408 AA306477 Hs 29379 hypothetical protein FLJ 10687 364
441466 AW673081 Hε 54828 ESTε 363
414013 AA766605 Hs 47099 hypothetical protein FLJ21212 362
420056 AW043684 Hs 99804 ESTε 362
424886 H88584 Hs 96900 hypothetical protein, KIAA1830 protein 362
431774 BE348813 Hs 268561 hypothetical protein FLJ 10726 362 435990 AI015862 Hs 131793 ESTs 362
417821 BE245149 Hs 82643 protein tyrosine kinase 9 362
414715 AA587891 Hs 904 amylo-1,6 glucosidase, 4-alpha glucanotr 3 62
444484 AK002126 Hs 11260 hypothetical protein FLJ11264 362
417008 AA191708 Hs 325825 Homo sapiens cDNA FLJ20848 fis, clone AD 362
413823 AI341417 Hs 29406 ESTs 3 61
435354 AA678267 Hs 117115 ESTs 360
427832 AF038362 Hs 180930 TBP-associated factor 172 360
427846 AW499770 Hs 180948 KIAA0729 protein 3 60
426116 AA868729 Hs 144694 ESTs 3 60
457635 AV660976 Hs 3569 hypothetical protein 360
443998 A1620661 Hs 296276 ESTs 360
417867 AW952547 Hs 194603 ESTs, Moderately similar to I38022 hypot 358
418182 AW016405 Hs 16648 ESTs 358
434941 AW073202 Hs 334825 Homo sapiens cDNA FLJ14752 fis, clone NT 358
424831 H61453 ESTs 3 58
448410 AK000227 Hs 21126 hypothetical protein FLJ20220 3 58
421823 N40850 Hs 28625 ESTs 3 58
414781 D50917 Hs 77293 KIAA0127 gene product 357
427393 AB029018 Hs 177635 KIAA1095 protein 357
415664 NM 004939 Hs 78580 DEAD/H (Asp-Glu Ala Aεp/His) box polypep 356
425465 L18964 Hs 1904 protein kinase C, iota 3 56
417124 BE122762 Hs 25338 ESTs 356
416602 NM 006159 Hs 79389 Protein kinase C-bindmg protein NELL2 356
419490 NM 006144 Hε 90708 granzyme A (granzyme 1 , cytotoxic T-lymp 3 55
421097 AI280112 Hε 125232 Homo sapiens cDNA FLJ13266 fis, clone OV 355
410390 AA876905 Hs 125286 ESTs 354
442073 AW973443 Hs 8086 RNA (guaπιne-7-) methyltransferase 354
435266 AK001942 Hε 4863 hypothetical protein DKFZp566A1524 354
441499 AW298235 Hs 101689 ESTs 354
453256 AI565587 Hs 32556 KIAA0379 protein 354
414142 AW368397 Hs 334485 hemicentin (fibulin 6) 354
438023 AF204883 Hs 6048 FEM 1 (C elegans) homolog b 354
412245 AI952669 Hs 22883 ESTs, Weakly similarto I38022 hypotheti 354
424144 AA454033 Hs 41644 AKAP-aεsxiated sperm protein 353
446682 AW205632 Hs 211198 ESTs 3 52
431392 AI371223 Hs 288671 Homo sapiens cDNA FLJ11997 fis, clone HE 352
433430 AI863735 ESTs 352
420394 AB023161 Hs 97403 KIAA0944 protein 352
425383 D83407 Hs 156007 Down syndrome critical region gene 1-lιk 352
443547 AW271273 hypothetical protein FLJ12666 352
420676 AI434780 Hs 4248 vav 2 oncogene 351
410690 AA322979 Hs 130266 ESTs 350
459645 AA074346 ESTs 350
401403 Target Exon 350
451166 T98171 Hs 185675 ESTs 350
418836 AI655499 Hs 161712 ESTε 350
421462 AF016495 Hs 104624 aquapoπn 9 350
414555 N98569 Hs 76422 phoεpholipase A2, group IIA (platelets, 350
432401 NM 013330 Hs 274479 NME7 349
408392 U28831 Hs 44566 KIAA1641 protein 349
425836 AW955696 Hs 90960 ESTs 348
452327 AK000196 Hs 29052 hypothetical protein FLJ20189 348
418721 NM 002731 Hs 87773 protein kinase, cAMP-dependent, catalyti 348
433627 AF078866 Hs 284296 Homo sapienε cDNA FLJ22993 fiε, clone K 348
422960 AW890487 cadhenn 13, H-cadheππ (heart) 348
430570 AI417881 Hs 292464 ESTε 348
406387 Target Exon 347
416585 X54162 Hs 79386 leiomodin 1, εm∞th muεcle (LMOD1) (Thy 346
432340 AA534222 gb nj21d02 s1 NCI.CGAP.AAI Homo sapienε 346
412240 H72176 hypothetical protein FLJ13159 346
450937 R49131 Hs 26267 ATP-dependaπt interferon reεponεe protei 346
443634 H73972 Hs 134460 ESTε 346
422963 M79141 Hs 13234 ESTs 346
424954 NM 000546 Hs 1846 tumor protein p53 (Li Fraumeπi syndrome) 346
433437 U20536 Hs 3280 caspase 6, apoptosis related cysteine pr 346
425100 AF051850 Hs 154567 supervillin 345
450680 AF131784 Hs 25318 Homo sapiens clone 25194 mRNA sequence 345
444250 R40815 Hs 12396 ESTs, Weakly similar to 2004399A chromos 344
428386 R17298 Hs 295923 seven in absentia (Drosophila) homolog 1 344
447764 NM.003776 Hs 19500 nuclear Ixalization signal deleted in v 344
411251 R19774 Hs 22835 HHGP protein 344
432648 AA557952 gb nl17c05 s1 NCLCGAP.HSC1 Homo εapiens 344
428708 NM 014897 Hs 190386 KIAA0924 protein 344
437233 D81448 Hs 339352 Homo sapiens brother of CDO (BOC) mRNA, 343
451743 AW074266 Hε 23071 ESTs 342
453258 AW293134 Hε 32597 ring finger protein (C3H2C3 type) 6 342
448705 H05072 Hε 124984 ESTs, Moderately similar to ALU7 HUMAN A 342
414489 AI620677 Hε 73105 ESTε 342
429732 U20158 Hε 2488 lymphocyte cytosolic protein 2 (SH2 doma 341
435841 R28522 Hs 186937 ESTs 341
424130 AL050136 Hs 140945 Homo sapiens mRNA, cDNA DKFZp586L141 (fr 340
451198 AW964541 hypothetical protein FLJ21127 340 428852 AF080158 Hs 226573 inhibitor of kappa light polypeptide gen 340
436023 T81819 Hs 302251 ESTs 340
449656 AA002008 Hs 188633 ESTs 340
437739 AW579216 Hs 264610 ESTs, Moderately similar to Ibd1 [H sapi 340
429617 X89984 Hs 211563 B-cell CLL/lymphoma 7A 340
448474 AI792014 Hs 13809 hypothetical protein FU 10648 340
456505 AA504595 ESTs 340
439867 AA847510 Hε 161292 ESTε 340
442113 BE622187 ESTε, Weakly similar to I38022 hypotheti 340
425922 AL157466 Hs 162751 Homo sapienε mRNA, cDNA DKFZp761E2423 (f 340
435299 AI745458 Hs 343026 ESTε, Weakly similar to T20593 hypotheti 340
421263 AB020638 Hs 103000 KIAA0831 protein 340
410300 AW903988 Hε 62119 hypothetical protein FLJ 14800 3 39
440028 AW473675 ESTs, Weakly similar to T17227 hypotheti 3 39
454070 N79110 Hε 21276 collagen, type IV, alpha 3 (Goodpasture 338
432572 AI660840 Hε 191202 ESTs, Weakly similar to ALUE.HUMAN "" 338
442426 AI373062 Hs 332938 hypothetical protein MGC5370 338
428412 AA428240 Hs 126083 ESTε 338
448772 AW390822 Hs 301528 L-kyπurenine/alpha-aminoadipate aminotra 338
417067 AJ001417 Hs 81086 solute camerfamily 22 (extraπeuronal 338
413714 AI560944 Hs 71428 ESTs 338
415663 AW296841 Hs 313332 ESTs 338
407904 W44735 Hs 9286 Homo sapienε cDNA FLJ21278 fis, clone C 337
421114 AW975051 Hs 293156 ESTs, Weakly similar to I78885 seππe/th 337
440214 AA247118 Hs 7049 hypothetical protein FLJ 11305 337
440980 AL042005 Hs 1117 tπpeptidyl peptidase II 336
411975 AI916058 Hs 144583 ESTs 336
450330 AW500775 Hs 24817 hypothetical protein FLJ20136 336
414783 AW069569 unactive progesterone rxeptor, 23 kD 336
436043 AW963838 Hε 168830 Homo sapienε cDNA FLJ12136 fiε, clone MA 336
414646 AA353776 Hs 901 CD48 antigen (B-cell membrane protein) 336
411213 AA676939 Hs 69285 neuropil 1 3 36
420613 AI873871 Hs 7041 ESTε, Weakly similar to A47582 B cell gr 335
417534 NM 004998 Hs 82251 myosin IE 335
431698 AI492369 ESTs 335
423915 AF039018 Hs 135281 alpha-xtιnιn-2-asεocιated LIM protein 335
441623 AA315805 desmoglein 2 334
420729 AW964897 Hs 290825 ESTs 334
440010 AA534930 Hs 127236 hypothetical protein FLJ 12879 334
448369 AW268962 Hs 111335 ESTs 334
452820 N46161 Hs 35274 ESTs 334
453271 AA903424 Hs 6786 ESTs 334
428839 AI767756 Hs 82302 Homo sapienε cDNA FLJ14814 fis, clone NT 334
418832 X04011 Hs 88974 cytxhrome b-245, beta polypeptide (chro 334
443291 AA325633 Hs 136102 KIAA0853 protein 333
418720 AI381687 Hε 39526 ESTs 333
452107 AB020681 Hs 27973 KIAA0874 protein 333
439943 AW083789 Hs 124620 ESTs 333
433282 BE539101 hypothetical protein 333
410344 AW978436 Hs 62515 KIAA0494 gene product 333
417259 AW903838 Hs 81800 chondroitin sulfate proteoglycan 2 (vers 332
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 332
434210 AA665612 ESTε 332
431923 AI741770 Hs 292690 ESTε, Weakly similar to I38022 hypotheti 332
453199 AI336266 Hs 32353 mitogen-xtivated protein kinase kinaεe 332
419534 AA443691 Hs 90858 Homo εapiens clone 25023 mRNA sequence 332
448939 BE267795 Hs 22595 hypothetical protein FLJ10637 332
433312 AI241331 Hs 131765 ESTs, Moderately similarto 138937 DNA/R 332
422092 AB007883 Hs 111373 KIAA0423 protein 332
412262 W26406 seven in absentia (Drosophila) homolog 1 332
425071 NM_013989 Hs 154424 deiodmase, lodothyroniπe, type II 332
446094 AK001760 Hs 13801 KIAA1685 protein 332
446493 AK001389 Hs 15144 hypothetical protein DKFZp564O043 332
420339 AW968259 Hs 186647 ESTs 331
447735 AA775268 Hs 6127 Homo sapiens cDNA FLJ23020 fis, clone L 331
432331 W37862 Hs 274368 MSTP032 protein 331
433697 AA600357 Hs 239489 TIA1 cytotoxic granule-assxiated RNA-bi 331
419231 AL046294 Hs 136245 ESTs, Weakly similar to T17227 hypotheti 331
430950 AA489525 ESTs 330
409758 AW474960 Hε 182258 ESTs, Weakly similar to I78885 seπne/th 330
417958 AA767382 Hε 193417 ESTs 330
410763 AF279145 Hs 8966 hypothetical protein FLJ21776 330
419543 AA244170 gb nc05h02 s1 NCI.CGAP.Pr1 Homo sapiens 330
454024 AA993527 Hs 293907 hypothetical protein FLJ23403 330
452039 AI922988 Hs 172510 ESTs 330
443798 R07848 Hs 188522 ESTs 329
449378 AW664026 Hs 59892 ESTs 329
455657 BE065209 gb RC1-BT0314-310300015 b12 BT0314 Homo 328
420126 NM 016255 Hs 95260 Autosomal Highly Conserved Protein 328
444291 AI598022 Hs 193989 TAR DNA binding protein 328
424084 AI940675 Hs 20914 hypothetical protein FLJ23056 328
437330 AL353944 Hs 50115 Homo sapiens mRNA, cDNA DKFZp761J1112 (f 328
443774 AL117428 Hs 9740 DKFZP434A236 protein 328 425657 T89839 Hs 119471 ESTs 328
406672 M26041 Hs 198253 major histocompatibility complex, class 3 28
419905 AW248229 Hs 93659 protein disulfide isomerase related prot 327
425332 AA633306 Hs 1 7279 ESTs 3 27
418529 AW005695 Hs 250897 TRK-fused gene 327
417944 AU077196 Hs 82985 collagen, type V, alpha 2 327
433618 AA602539 Hs 345494 ESTs 327
408630 AA748009 Hs 173328 ESTs 326
415914 AA306033 Hs 78915 GA-bindmg protein transcnption factor, 326
415102 M31899 Hs 77929 excision repair cross-complementing rode 326
432626 AA471098 Hs 278544 acetyl Coenzyme A acetyltraπsferase 2 (a 326
429493 AL134708 Hs 145998 ESTs 326
445860 AA332145 Hs 13392 tethering factor SEC34 326
450256 AA286887 Hs 24724 MFH-amplified sequenceε with leucme-πc 3 26
426083 AW962712 Hs 126712 ESTs, Weakly similar to AF191020 1 E2IG5 3 26
420059 AF161486 Hs 94769 RAB23, member RAS oncogene family 326
448412 AI219083 Hs 42532 ESTs, Moderately similar to ALU8 HUMAN A 326
436758 AW977167 Hs 155272 ESTs 326
438011 BE466173 Hs 145696 splicing factor (CC1 3) 326
426354 NM 004010 Hs 169470 dystrophin (muscular dystrophy, Duoheπne 3 25
426860 U04953 Hs 172801 isoleucme-tRNA synthetase 3 25
437830 AB020658 Hs 5867 KIAA0851 protein, suppressor of xtin 1 3 25
453368 W20296 Hs 288178 Homo sapiens cDNA FLJ 11968 fis, clone HE 325
409939 AA463437 Hs 11556 Homo sapiens cDNA FLJ12566 fis, clone NT 325
413715 AW851121 Hs 75497 Homo sapiens cDNA FLJ22139 fis, clone H 324
407939 W05608 Hs 312679 ESTs, Weakly similar to A49019 dynein he 324
418283 S79895 Hs 83942 cathepsin K (pycnodysostosis) 324
414405 AI362533 KIAA0306 protein 324
445893 AI610702 Hs 202613 ESTs, Weakly similar to TRHY.HUMAN TRICH 324
434423 NM 006769 Hs 3844 UM domain only 4 324
408951 AW407227 Hs 227591 hypothetical prote FLJ 11088 324
408949 AF189011 Hs 49163 putative πbonuclease III 3 24
410337 M83822 Hs 62354 cell division cycle 4-lιke 324
409010 AI648675 Homo sapiens, Similarto RIKEN cDNA 1700 3 24
400419 AF084545 Target 3 24
454078 AA601518 Hs 22209 sxreted modular calcium-binding protein 324
422461 NM 003417 Hs 117077 zinc finger protein 264 3 24
441604 AI683049 Hs 201282 ESTs 324
411960 R77776 Hs 18103 ESTs 323
414895 AW894856 Hs 116278 Homo sapiens cDNA FLJ13571 fis, clone PL 323
430522 N75750 Hs 242271 KIAA0471 gene product 323
426490 NM.001621 Hs 170087 aryl hydrxarbon rxeptor 323
405268 ENSP00000223174* KIAA0783 PROTEIN 323
429165 AW009886 Hs 118258 prostate cancer assxiated protein 1 322
427196 AW967522 Hs 191593 ESTε 322
439776 AL360140 Hs 176005 Homo sapiens mRNA full length insert cDN 322
417727 AL133623 Hs 82501 similar to mouse Xrn1 / Dhm2 protein 322
410853 H04588 Hs 30469 ESTs 322
411962 AA099050 gb zk85d12 r1 Soares _pregnanLuterus_NbH 322
451099 R52795 Hs 25954 interleukin 13 rxeptor, alpha 2 322
440452 AI925136 Hs 55150 ESTs, Weakly similar to CAYP_HUMAN CALCY 322
427480 BE148769 Hs 334477 hypothetical protein FLJ11328 322
444623 AI183829 Hs 202111 ESTs 321
424006 AF054815 Hs 137548 CD84 antigen (leukxyte antigen) 3 21
435874 AA868688 Hs 93102 ESTs 320
443801 AW206942 Hs 253594 intron of tπchorhinophalangeal syndro 320
434982 AW975084 gb EST387190 MAGE resequences, MAGN Homo 320
430929 AA489166 Hs 156933 ESTs 320
426316 NMJ02430 Hs 268515 meningioma (disrupted in balanced transi 320
430378 Z28572 Hs 2556 tumor nxrosis fxtor rxeptor superfami 320
422109 S73265 Hs 1473 gastπn-releasing peptide 320
451119 AA805417 Hs 64753 ESTε 320
414893 AA215295 Hs 77578 ubiquitin εpxific protease 9, X chromos 320
432676 AI187366 gb qf29c01 x1 Soareε.testis.NHT Homo εap 3 19
428820 AA436187 Hs 172631 integπn, alpha M (complement component 3 19
422040 AA172106 Hs 110950 Rag C protein 318
437838 AI307229 ESTs 318
408761 AA057264 Hs 238936 ESTs, Weakly similar to (defline not ava 318
420789 AI670057 Hs 199882 ESTs 318
419135 R61448 Hs 106728 ESTs, Weakly similar to KIAA1353 protein 318
446019 AI362520 histone deacetylase 3 318
430848 AW021726 Hs 345490 gb df27e02 y1 Morton Fetal Cxhlea Homo 318
425375 AA631977 Hs 155995 KIAA0643 protein 318
424075 AI807320 Hs 227630 RE1-sιlencing transcnption fxtor 318
413802 AW964490 Hs 32241 ESTs, Weakly similar to S65657 alpha-1 C- 3 18
453111 AB014598 Hs 31720 hephaestm 3 18
454042 H22570 hypothetical protein FLJ20093 3 18
407756 AA116021 Hs 38260 ubiquitin specific protease 18 318
447183 AI554733 Hs 173182 ESTs 3 18
437446 AA788946 Hs 101302 ESTs, Moderately similar to CA1 C RAT COL 3 18
431831 AW023204 Hs 302743 ESTs 3 18
420664 AI681270 Hs 99824 BCE-1 protein 318
451582 AI963026 Hs 289958 ESTs, Weakly similar to putative p150 [H 317 432954 AI076345 ESTs 3 17
444990 AI912410 Hs 27475 Homo sapiens cDNA FLJ12749 fis, clone NT 317
427373 AB007972 Hs 130760 myosin phosphatase, target subunit 2 3 17
408832 AW085690 Hs 63428 ESTs, Weakly similar to Z195JHUMAN ZINC 317
441889 AI090455 Hs 268371 hypothetical protein FLJ20274 317
416959 D28459 Hs 80612 ubiquitiπ-conjugatiπg enzyme E2A (RAD6 h 316
445525 BE149866 Hs 14831 Homo sapiens, Similar to zinc finger pro 316
420623 BE245485 Hs 99437 Homo sapiens mRNA, cDNA DKFZp586G1924 (f 316
451475 T19093 Hs 26450 KIAA0725 protein 3 16
452066 AA772149 Hs 16979 ESTs, Weakly similar to A43932 mucin 2 p 3 16
429556 AW139399 Hs 98988 ESTs 3 16
448514 AB020626 Hs 301866 KIAA0819 protein 316
443732 AI188803 Hs 153944 ESTs 316
436805 AA731533 Hs 270751 ESTs 3 16
430057 AW450303 Hs 2534 bone morphogeπetic protein receptor, typ 316
417511 AL049176 Hs 82223 chordin like 3 16
423595 R82826 Hε 220702 ESTs 316
445837 AI261700 Hε 145544 ESTs 316
418068 AW971155 Hε 293902 ESTs, Weakly similar to ISHUSS protein d 316
430253 AK001514 Hε 236844 hypothetical protein FLJ 10652 3 16
414183 AW957446 Hε 301711 ESTs 3 16
433194 AB040883 Hs 83243 KIAA1450 protein 3 16
453915 AA588721 Hs 286218 πbosomal protein L44 3 15
407725 BE388094 Hs 21857 ESTs 315
437412 BE069288 Hs 34744 Homo sapiens mRNA, cD A DKFZp547C136 (fr 314
440937 AF202724 Hε 7531 KIAA0810 protein 314
449057 AB037784 Hε 22941 KIAA1363 protein 314
446126 AW085909 plxkstπn homology domain interacting p 314
407204 R41933 Hε 140237 ESTs, Weakly similar to ALU 1.HUMAN ALU S 314
419145 N99638 gb za39g11 r1 Soares fetal liver splxn 314
418757 AI864193 Hε 169728 hypothetical protein FLJ13150 314
430000 AW205931 Hs 99598 hypothetical protein MGC5338 314
437296 AA350994 Hs 20281 KIAA1700 314
441381 H22195 Hs 31874 ESTs 3 14
457250 AA811987 Hε 125779 ESTs 314
422900 AA641201 Hε 222051 ESTs 3 14
442787 W93048 Hs 250723 hypothetical protein MGC2747 314
430589 AJ002744 Hs 246315 UDP-N acetyl alpha-D-galxtosamine polyp 314
419355 AA428520 Hs 90061 progesterone binding protein 314
409509 AL036923 Hs 322710 ESTs 314
417308 H60720 Hs 81892 KIAA0101 gene product 3 14
409799 D11928 Hs 76845 phosphoseπne phosphatase-hke 3 14
429160 AW663083 Hs 144469 ESTs 3 14
452679 Z42387 Hs 83883 transmembrane, prostate androgen induced 314
451107 AA235108 Hs 17639 Homo sapieπε ubiquitin protein ligase (U 314
444034 AL161957 Hs 10177 plxkstπn homology domain interxtmg p 314
451518 AW340925 Hs 174918 ESTs 314
435702 AI033647 Hs 121001 Homo sapienε, clone IMAGE 3460280, mRNA 313
439208 AK000299 Hs 180952 dynactm 4 (p62) 3 13
451838 AW005866 Hs 193969 ESTs 3 13
426369 AF134157 Hs 169487 Kreiεler (mouse) maf-related leucine zip 313
446945 AI193115 Hs 16611 tumor protein D52-lιke 1 3 13
453920 AI133148 Hs 36602 I factor (complement) 313
411529 AA430348 Hs 317596 Homo sapienε cDNA FLJ12927 fis, clone NT 313
417105 X60992 Hs 81226 CD6 antigen 312
433854 AA610649 Hs 333239 ESTs 312
408089 H59799 Hs 42644 thioredoxin-like 312
453686 AL110326 Hs 304679 ESTs, Moderately similar to Z195.HUMAN Z 312
426167 AF039023 Hs 167496 RAN binding protein 6 312
452195 AA994712 Hs 116878 ESTs 312
416580 T61572 Hs 79385 Human clone 23574 mRNA sequence 312
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet-x 312
424001 W67883 Hs 137476 paternally expressed 10 312
434584 D57341 Hs 188361 Homo sapienε cDNA FLJ12807 fiε, clone NT 312
433401 AF039698 Hs 284217 εerologically defined xlon cancer antig 3 12
409245 AA361037 tRNA lεopeπtenylpyrophoεphate traπεferaε 312
414290 AI568801 Hs 71721 ESTε 3 12
400294 N95796 Hs 278695 Homo εapiens praεtem mRNA, complete cdε 312
429819 AL133011 Hs 225108 Homo sapiens mRNA, cDNA DKFZp434P201 (fr 311
448873 NM 003677 Hs 22393 density-regulated protein 311
428471 X57348 Hs 184510 εtratifin 311
436288 AI361722 Hs 192410 ESTs 310
433376 AI249361 Hs 74122 caspase 4, apoptosis-related cysteine pr 310
416051 AA835868 Hs 25253 mannosidase, alpha, class 1A, member 1 3 10
453468 W00712 Hs 32990 DKFZP566F084 protein 310
412340 AA101809 Hs 182685 ESTs 310
438716 AA814903 Hs 155113 ESTs 310
419440 AB020689 Hs 90419 KIAA0882 protein 310
433017 Y15067 Hs 279914 zinc finger protein 232 310
428513 BE220806 Hs 184697 plexm C1 3 10
437866 AA156781 metallothione 1E (functional) 3 10
451027 AW519204 Hs 40808 Homo sapiens Similar to RIKEN cDNA 2810 3 10
448030 N30714 Hs 325960 membrane spanning 4-domaιns, subfamily A 310 435445 AA737345 Hs 294041 ESTs 3 10
420997 AK001214 Hs 100914 hypothetical protein FLJ10352 309
449924 W30681 Hs 146233 Homo sapiens cDNA FLJ22130 fis, clone H 309
406122 Target Exon 309
435272 AA906415 Hs 110041 ESTs 309
410726 AI623859 Hs 15936 ESTs 3 09
413063 AL035737 Hs 75184 chitiπase 3-lιke 1 (cartilage glycoprote 3 08
407949 W21874 Hs 247057 ESTs, Weakly similar to 2109260A B cell 308
417538 AW050865 Hs 275711 hypothetical protein MGC2452 308
434938 AW500718 Hs 8115 Homo sapiens, clone MGC 16169, mRNA, com 308
434733 AI334367 Hs 159337 ESTs 3 08
434421 AI915927 Hs 34771 ESTs 308
407930 AA045847 Hs 188361 Homo sapiens cDNA FLJ12807 fis, clone NT 308
424939 AK000059 Hs 153881 Homo sapiens NY-REN 62 antigen mRNA, par 308
458332 AI000341 ESTs 3 08
445034 AW293376 Hs 143659 ESTs 308
446570 AV659177 Hs 127160 ESTs 308
429920 AW473208 Hs 115572 ESTs, Weakly similar to I38022 hypotheti 308
459513 AI032946 gb ox06g09 s1 Soares fetal liver spleen 306
419038 AW134924 Hs 190325 ESTs 3 06
451079 AI827988 Hs 240728 ESTs, Moderately similar to PC4259 fern 306
417386 AL037228 Hs 82043 D123 gene product 306
453108 AI311457 Hs 99472 ESTs 306
449328 AI962493 ESTs 3 06
428656 AB037798 Hs 188790 KIAA1377 protein 306
425509 AF079363 Hs 158213 εperm assxiated antigen 6 306
447957 NM 014821 Hs 20126 KIAA0317 gene product 306
417226 AW505054 Hs 4283 ESTs 305
452248 AA093668 Hs 28578 musclebl d (Drosophιla)-lιke 305
426279 AI648520 Hs 169084 tubby like protein 3 305
433814 AA609738 Hs 16525 ESTs 305
453064 R40334 Hs 89463 potassium large conductance calcium-xti 305
431341 AA307211 Hs 251531 proteasome (prosome, macropain) subunit, 304
441789 D52059 Hs 7972 KIAA0871 protein 304
456437 AI924228 Hs 115185 ESTs, Moderately similarto PC4259 fern 304
438771 NM 016289 Hs 6406 M025 protein 304
448497 BE613269 Hs 21893 hypothetical protein DKFZp761N0624 304
416240 NM.001981 Hs 79095 epidermal growth factor receptor pathway 3 04
409038 T97490 Hs 50002 small inducible cytokine subfamily A (Cy 3 04
424776 AI867931 Hs 164595 ESTs 3 03
408409 AW838181 Hs 278337 Homo sapiens cDNA FLJ11537 fis, clone HE 303
429693 BE254962 Hs 211612 SEC24 (S cerevisiae) related gene famil 303
425960 AW410646 Hs 164649 hypothetical protein DKFZp434H247 303
431625 AW750627 Hs 6634 Homo sapienε cDNA FU22547 fis, clone H 3 03
451144 AW956103 Hs 61712 pyruvate dehydrogenase kinase, isoenzyme 3 02
432274 AK000382 Hs 274251 hypothetical protein FLJ20375, KIAA1797 3 02
408683 R58665 Hs 46847 TRAF and TNF rxeptor-assxiated protein 302
427735 AA916785 Hs 180610 splicing factor proline/glutamiπe πch ( 302
440603 AL121733 Hs 7299 Novel human gene mapping to chomosome 1 302
415443 T07353 Hs 7948 ESTs 302
439981 AI348408 Hs 124675 ESTs, Weakly similar to T14742 hypotheti 302
406685 M18728 gb Human noπspxific crossrexting antig 302
446013 AI360167 Hs 152774 ESTε 302
433902 AW292820 Hs 144906 ESTs 302
412610 X90908 Hs 74126 fatty xid binding protein 6, ileal (gas 302
432505 AW274526 Hs 277721 KIAA0049 301
440040 BE219431 Hs 302031 zinc finger protein, subfamily 1A, 4 (Eo 301
433255 AI274270 Hs 96840 KIAA1527 protein 3 01
419726 U50330 Hs 1274 bone morphogeπetic protein 1 301
417258 N58885 gb yy60a09 s1 Soareε multiple εcleroεiε 300
435800 AI248285 Hs 118348 ESTε 300
444838 AV651680 Hs 208558 ESTε 300
456760 AW961251 Hε 127828 guanine nucleotide binding protein (G pr 300
408360 AI806090 Hs 44344 hypothetical protein FU20534 3 00
427982 NM.016156 Hs 181326 KIAA1073 protein 3 00
436396 AI683487 Hs 152213 wingleεε-type MMTV integration εite farm 3 00
410434 AF051152 Hs 63668 toll-like rxeptor 2 300
412095 AI624707 Hs 5921 Homo εapiens cDNA FLJ21592 fis, clone C 300
425955 T96509 Hs 248549 ESTs, Moderately similar to S65657 alpha 298
450247 AF123303 Hs 24713 hypothetical protein 298
417865 AW086059 Hs 6529 ESTs, Weakly similar to I78885 seπne/th 298
415457 AW081710 Hs 7369 ESTs, Weakly similar to ALU1 HUMAN ALU S 298
438543 AA810141 Hs 192182 ESTs 2 98
415503 U36601 Hs 78473 N-dexetylase/N-sulfotransferase (hepara 2 98
429138 AB020657 Hs 197298 NS1-bιndιng protein 298
447881 BE620886 GCN1 (general control of ammo-xid syπt 296
425481 AW978162 ESTs 296
453315 BE544203 Hs 24831 ESTs 296
440638 AI376551 gb te64e10 x1 Soares NFL T GBC S1 Homo s 2 95
433208 AW002834 Hs 24095 ESTs 295
442495 AI184717 ESTs 294
418858 AW961605 Hs 21145 hypothetical protein RG083M052 294
408170 AW204516 Hε 31835 ESTs 294 430382 AA477908 Hs 282267 ESTs, Moderately similar to I38022 hypot 294
449765 N92293 Hs 206832 ESTs, Moderately similar to ALU8 HUMAN A 294
407361 AA744622 Hs 292645 ESTs, Weakly similar to ALU5.HUMAN ALU S 294
407910 AA650274 Hs 41296 fibronectin leucine rich transmembrane p 293
436005 BE551650 Hs 158126 Homo sapiens cDNA FLJ13350 fis, clone OV 293
449458 AI805078 Hs 208261 ESTs 293
449317 AW293413 Hs 132906 19A24 protein 292
411118 N27944 Hs 221476 ESTε, Weakly similar to AF108460 1 ubinu 292
449494 AW237014 Hs 315369 Homo sapiens cDNA FLJ23075 fis, clone L 291
416311 D80529 gb HUM081H05B Human fetal brain (TFujiwa 291
433068 NM 006456 Hs 288215 sialyltransferase 290
429272 W25140 Hs 110667 ESTs 290
432519 AI221311 Hs 130704 ESTε, Weakly similar to BCHUIA S-100 pro 290
445467 AI239832 Hs 15617 ESTs, Weakly similar to ALU4 HUMAN ALU S 288
426782 R14614 Hs 33846 ESTs 288
426216 N77630 Hs 13895 Homo sapiens cDNA FLJ 11654 fis, clone HE 288
413882 AA132973 Hs 184492 ESTs 288
421554 AW137676 Hs 97775 ESTs 288
446488 AB037782 Hs 15119 KIAA1361 protein 284
421391 AW304350 Hs 191958 immunoglobulin superfamily rxeptor traπ 284
424527 AW138558 Hs 334873 ESTs, Weakly similar to I54374 gene NF2 282
419284 AW820869 Hs 215658 ESTs, Moderately similar to ZN91 HUMAN Z 282
415788 AW628686 Hε 78851 KIAA0217 protein 282
448481 W15284 Hs 74832 ESTs 282
410491 AA465131 Hs 64001 Homo sapienε clone 25218 mRNA sequence 280
443441 AW291196 Hs 92195 ESTs 280
422725 AA315703 Hs 199993 ESTs, Weakly similar to ALUB.HUMAN «» 280
431926 AW972724 gb EST384816 MAGE resequences, MAGL Homo 280
420406 AA741024 Hs 88378 ESTs 279
437678 AA829860 Hs 122834 ESTs 278
440115 R41808 Hs 144924 ESTs, Weakly similar to B Chain B, Solut 78
439883 AL359652 Hs 171096 Homo sapiens EST from clone DKFZp434A041 278
446428 AW082270 Hs 12496 ESTs, Weakly similar to ALU4.HUMAN ALU S 277
451273 NM 014811 Hs 26163 KIAA0649 gene product 276
435154 AA668764 ESTs 276
432451 AW972771 Hs 292471 ESTs, Weakly similar to ALU1 HUMAN ALU S 275
442703 AL044949 Hs 116298 ESTε 274
419341 N71463 Hε 118888 ESTε, Weakly similar to ALULHUMAN ALU S 274
435861 AF254956 Hε 16608 candidate tumor suppressor protein 272
420137 AA306478 Hε 95327 CD3D antigen, delta polypeptide (TιT3 co 270
438441 AW664960 Hs 205319 ESTs 270
426158 NM 001982 Hs 199067 v-erb-b2 avian erythroblastic leukemia v 267
432882 NM.013257 Hs 279696 serum/gluc∞orticoid regulated kinase Ii 266
416239 AL038450 Hs 48948 ESTs 262
434792 AA649253 Hs 132458 ESTε 260
424852 AI222779 Hε 144848 ESTε 258
425638 NM 012337 Hs 158450 nasopharyngeal epithelium spxific prote 2.57
419551 AW582256 Hs 91011 anteπor gradient 2 (Xenepus laevis) hom 256
450571 AF158240 Hs 60397 ESTε 256
442435 AI986208 Hs 244760 ESTε, Highly similar to B34087 hypotheti 256
424148 BE242274 Hs 1741 integnn, beta 7 2.56
445784 AI253155 Hs 146065 ESTs 253
408072 BE005566 Hs 16773 Homo εapienε clone TCCCIA00427 mRNA εequ 252
434779 AF153815 Hs 50151 potaεsiu inwardly-rxtify g channel, s 252
450295 AI766732 Hs 210628 ESTs 248
440381 AA917808 Hε 190495 ESTs 246
433923 AI823453 Hs 146625 ESTs 244
420802 U22376 Hs 1334 v-myb avian myeloblastosiε viral oncogen 244
429670 L01087 Hε 211593 protein kinaεe C, theta 244
437908 AI082424 ESTs 243
438676 AA813745 Hs 123446 ESTs 237
410361 BE391804 Hs 62661 guanylate binding protein 1, interferon- 228
444969 AI203334 Hs 160628 ESTε 228
446423 AW139655 Hs 150120 ESTs 227
435517 AA928626 Hs 130177 ESTs 227
425354 U62027 Hs 155935 complement component 3a rxeptor 1 226
439180 AI393742 Hs 199067 v-erb-b2 avian erythroblastic leukemia v 200
429073 AA446167 Hs 47385 ESTs 1 98
433834 AA620742 Hs 130786 ESTs 1 72
417365 D50683 Hs 82028 transforming growth fxtor, beta rxepto 1 52
414521 D28124 Hs 76307 neurablastoma, suppression of tumoπgeni 1 30
402550 Target Exon 1 09
TABLE 33B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT Numbi Accession
431089 125941 2 BG940189AW063489AA715980 BF001091 BF880066 AA666102AA621946 AA491826
456034 685586 1 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
407192 2200202 1 AA602964AA609200 438089 22448.4 BM475665 BE644917 AW770789 AW952971 N64863 BM263259 AI224545 AI184866 N69114 AW518902 AI440169 AA809472 AV654440
AA281642 AU185230 AW337382 AI872923 AI537113 N73882 T83378 H63731 BF671764 AW897824 AI811204 AA344646 BE009112 BG899664
H91240 R60548 N41701
439195 21979.1 AF086037 H89360 H89546
432222 5395291 BG207209 BE166299 AI204995 BG199355 AW969908 AA52875S AW440776 BI044354
406687 00 M31126
444314 10279841 AW749625 AW749626 AW749644 AI140497
452239 101164 BG034853 AW173315 AW303375 BG190225 BG939153 BF057308 AA600736 AI751258 AI090486 BE939504 AW631492 AI768270 AI862133
AA417652 BE378218 AA599207 AW794702 AA024968 AA446024 AI148235 AI191710 BI493797 AI272646 BI493796 AA634323 AI754332
AA258414 C05155 AI218226 A1039656 AI350380 AI084698 AI754989 AI673545 AI432010 AI751035 AA375571 AA446297 BG216743
433586 32908.1 BC011194 AW517087 AA601054 T85512 418259 133853.1 BM310925 AA426110 BM310629 BF434286 AW015091 BF475996 AW118867 BE675186 AI688568 AI453594 AW590589 AI652425 AI827969
BF056946 AI802866 AI393380 AI476224 AW590639 AW136271 AI458252 AI524726 AA843768 AA782158 AI336058 A1097532 AW451563
AA459408 AA459633AA418444W23607 BG940150AI493445AW054729 AI221929 AI868744 AA215405 AA766713AA621546 BF928317
BE464132 AI990909 AW271459 AI262061 AA215404 N74332 BG940151 BG952261 AA972115 W96315 AA689586 R69057 BF766886 BE769254
W05240
432810 101919.1 BG292389 C06094 AI668930 AW104534 AA310513 AA830127 AW134897 AA046953 AW965490 AI810530 BF092924 AA334151 AA334725
D31302 R20723 AA263003 BI824635 AI276287 AI684428 AI524234 AI335035 AW014704 AI911443 AA972102 AI367512 AI126670 AW016017
AI286003 AI147163 AA626033 AI539156 AA565542 AI094253 AW512612 BE889628 AA744752 BE646306 AW471324 AA999975 AA863400
H17550 AI991439 R46187 BE929954 AA333976 D63102 BF744491
412652 18858.2 AI801777 BE677762 AW008210 AW009441 BE350994 BE207949 AI091475 AI802774 AI827533 AI075363 AI659979 AA687855 AI078125 AI090285
AA670058 AA602411 AA683472 AI436058 AA612826 AI038932 BG057726 AH 67355 BF449023 AI289476 AW074381 BF972912 AI991780
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437866 34267 1 U52054 AL581000 AA156850 AW293839 BI335865 AA024963 BF149420 BE073977 AW602574 BE164012 BE163992 BE163974 AW402161
BM194134 AW966609 W84374 BF916380 AA385173 W84366 AA383743 BF903598 AA043776 W84421 AA778446 AW444904 BF446960
AA837481 AV755539AW468444AW468002AA811830AA581806AI866686AI572124AA687333 D20160AA812489AU185248AU186004
AA156781 AI536733 BM144850 AI471883 AA040926 BF507639 AA043777 AW874142 BE832523 BE163972 BI022546 BI021204
458332 11396851 AI000341 AI766341 AW873274
459513 4178371 AV704062 BE162284 AI032946 BF360636
449328 30307261 AI884781 AI652306 AI651694 AI638744 AI962493
406685 0.0 M18728
417258 4008351 BG116781 BI914326 BI030196 N58885 N63406 AV683374 N58892 BG110501 AA333708 AA359583 AW963123 N95562 N95696 N95587
447881 446231 AK074291 AW293424 BE676135 AI832125 BE019146 BE465019 AI761124 AA617778 AI279232 AW575897 AI672039 F28618 BF924261
AA722184 BF934174 BE004328 AV749301 BE880282 BI019798 BI019389 BF928776 AW813409 AV726604 AA077560 BE272975 BF949119
AW814195 BE879126 AI697926 BF594155 BE205787 BF063513 N35828 AI948557 AI433839 A1379679 BG056182 AI589094 N23123 AA588805
AW316581 AI080272 AI421980 AI493318 BF194830 N87590 AA495993 N32996 AA699844 H96845 H96592 N28741 BI035539 BF747723
BF171066 W01350 H05495 AI243785 Z39622 AA887432 AI350659 R46102
425481 334120.2 AL520496AW978162AI610475AI688990AW470054AA609426AI167391 AA815231 AA358241 440638 371165.1 BG009500 AI376551 AA897445 T87714 442495 928718 1 At184717 AW518883 AF121173 416311 1280744.1 AA179446 AA357794 D81719 D80529 C14833 431926 1237041.1 AW972724 AA877998 AA522631 AU185388 435154 126605 1 AW972063 AA668764 AA804491 AW665688 AA765069 437908 13268.11 AI740586 AA771806 BE500996 AW204531 AI082424 AI033879 BF093176 AA771764 D38676
TABLE 33C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA εequence of human chromosome 22" Dunham, etal (1999) Nature 402489495 Strand Indicates DNA strand from which exonε were predicted
NLposition Indicates nucleotide poεitioπs of predicted exons Pkey Ref Strand Nt position
401403 7710966 Plus 146180-146294
406387 9256180 Plus 116229-116371,117512-117651
405268 4156151 Minus 24404-24521
406122 9144087 Minus 30940-31386 402550 7652009 Minus 80413-80673
TABLE 34A About 703 genes upregulated in idiopathic pulmonary fibrosis relative to hypersensitivity pneumonitis or non specific interstitial pneumonitis
Pkey Unique Eos probeset identifier number ExAccn Exemplar Accession number, Genbank acceεsioπ number UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of IPF Als divided by 90th percentile of HP Als, where the minimum value for the numerator and denominator was set to 50
R2 90th percentile of IPF Als divided by 90th percentile of NSIP Als, where the minimum value for the numerator and denominator was set to 50
Pkey ExAccn UnigenelD Unigene Title R1 R2
405443 Target Exon 966 750
418007 M13509 Hs 83169 matrix metalloprote ase 1 (interstitial 723 366
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopoπtin, 663 303
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 484 281
406964 M21305 FGENES predicted novel secreted protem 473 569
425259 AL049280 Hs 155397 Homo sapiens mRNA cDNA DKFZp564K143 (fr 434 434
407244 M10014 fibrinogen, gamma polypeptide 414 588
421823 N40850 Hs 28625 ESTs 412 1 80
419875 AA853410 Hs 93557 proenkephaliπ 390 201
409542 AA503020 Hs 36563 hypothetical protein FLJ22418 388 290
418310 AA814100 Hs 86693 ESTs 366 284
442006 AW975183 ESTs, Weakly similar to S72482 hypotheti 360 313
438315 R56795 Hs 82419 ESTs 349 3 70
425071 NM.013989 Hs 154424 deiodmase, lodothyromne, type II 347 1 38
409632 W74001 Hs 55279 seπne (or cysteine) proteinase inhibito 346 346
434233 AF119903 Hs 138453 hypothetical protein PR02834 328 251
408000 L11690 Hs 198689 bullous pemphigoid antigen 1 (230/240kD) 326 326
447033 AI357412 Hs 157601 Predicted gene Eos cloned, sxreted wΛ/ 319 212
420185 AL044056 Hs 251385 ESTs 318 301
420195 N44348 Homo sapiens cDNA FLJ11177 fis, clone PL 316 316
426682 AV660038 Hs 2056 UDP glycosyltransferase 1 family, polype 308 3 18
408221 AA912183 Hs 47447 ESTs 307 1 98
417079 U65590 Hs 81134 interieukin 1 rxeptor antagonist 302 236
419216 AU076718 Hs 164021 small inducible cytokine subfamily B (Cy 298 1 72
422163 AF027208 Hs 112360 prominiπ (mouse) like 1 287 1 8
422404 AL133571 Hs 336189 Homo sapiens mRNA, cDNA DKFZp434F1135 (f 280 266
445745 AB007924 Hε 13245 KIAA0455 gene product 278 1 65
407938 AA905097 Hs 85050 phospholamban 278 246
423575 C18863 Hε 163443 intron of peπoεtin (OSF-2oε) 278 1 55
446659 AI335361 Hs 226376 ESTs 274 1 56
425383 D83407 Hs 156007 Down syndrome cπtical region gene 1-lιk 274 1 85
437620 AW976930 ESTs 272 272
414591 AI888490 Hs 55902 ESTs, Weakly similar to ALU8.HUMAN ALU S 267 205
416585 X54162 Hs 79386 leiomodin 1, sm∞th muεcle (LMOD1) (Thy 266 1 47
425707 AF115402 Hs 11713 E74-lιke fxtor 5 (ets domain transcnpt 266 266
430712 AW044647 ESTs 262 262
453111 AB014598 Hs 31720 hephaeεtin 261 1 72
451099 R52795 Hs 25954 interieukin 13 receptor, alpha 2 259 1 27
414290 AI568801 Hs 71721 ESTs 259 1 23
417801 AA417383 Hs 82582 integπn, beta-like 1 (with EGF-like rep 258 258
412639 AW961284 Hs 203838 ESTs 258 229
423720 AL044191 Hs 23388 hypothetical protein DKFZp434F0318 257 1 74
429757 AW452355 Hs 256037 ESTs 257 1 60
429504 X99133 Hs 204238 lipocalin 2 (oncogene 24p3) (NGAL) 257 1 00
412228 AW603785 Hs 73792 complement component (3d/Epsteιn Barr vi 256 1 12
430223 NM 002514 Hs 235935 nephroblastoma overexpresεed gene 256 1 25
411880 AW872477 gb hm30f03 x1 NCI CGAP.Thy4 Homo εapiens 254 254
401645 C16001440* gι|12330704|gb|AAG52890 1|AF3 253 338
401673 C16001416* gι|12743112|ref]XP_010131 2| 247 283
449048 Z45051 Hs 22920 similarto S68401 (cattle) glucose indue 246 1 18
416316 H58721 Hs 271628 ESTs 242 344
453874 AW591783 Hs 36131 collagen, type XIV, alpha 1 (undulin) 240 1 69
451149 AL047586 RNA binding motif protein 8B 240 1 95
421190 U95031 Hs 102482 mucm 5, subtype B, trxheobranchial 240 1 61
410036 R57171 Hs 57975 calsequeslππ 2 (cardix muscle) 240 240
429525 N92540 Hs 205353 xtonuclxside tπphosphate drphosphohyd 239 1 27
405120 C4001445 gι|12697999|dbj|BAB21818 1| (AB 238 238
432224 AW189460 Hs 208358 ESTε 238 200
418663 AK001100 Hs 41690 desm∞ollin 3 238 238
412622 AW664708 Hs 171959 ESTs 237 1 63
424012 AW368377 Hs 137569 tumor protein 63 kDa with strong homolog 237 1 52
442767 AI017208 Hs 131149 ESTs 236 1 22
401785 NM 02275* Homo sapiens keratin 15 (KRT1 235 1 79
411800 N39342 Hs 103042 microtubule assxiated protein 1B 235 1 18
427535 R29543 Hs 2164 pro-platelet basic protein (includes pla 234 234
444009 AI380792 Hs 135104 ESTs 234 207
435143 R12375 Hs 194600 ESTs 233 1 68
402333 Target Exon 233 315
429609 AF002246 Hs 210863 cell adheεion molxule with homology to 233 1 10
454078 AA601518 Hs 22209 sxreted modular calcium-binding protein 232 1 30
452242 R50956 Hs 159993 gycosyltransferase 232 1 45
418693 AI750878 Hs 87409 thrombospondm 1 232 232
428411 AW291464 Hs 10338 ESTs 232 1 54
459702 AI204995 gb aπ03c03 x1 Stratagene schizo brain S1 231 1 98
428839 AI767756 Hs 82302 Homo sapienε cDNA FLJ14814 fis, clone NT 231 249
427138 N77624 Hs 173717 phosphatidic acid phosphatase type 2B 231 1 32 422363 T55979 Hs 115474 replication factor C (activator 1) 3 (38 230 230
456536 AW135986 Hs 257859 ESTs 228 228
428166 AA423849 Hs 79530 M5-14 protein 227 1 88
456936 M81349 Hs 1955 serum amyloid A4, constitutive 225 216
417728 AW138437 Hs 24790 KIAA1573 protein 225 1 37
453070 AK001465 Hs 31575 SEC63, endoplasmic reticulum traπslocon 2 24 242
409159 AW673312 Hs 50848 hypothetical protein FLJ20331 224 224
404942 splicing factor, argiπiπe/εeππe πch 9 2 24 264
410286 AI739158 Hs 61898 DKFZP586N2124 protein 224 246
440516 S42303 Hs 161 cadhenn 2, type 1, N cadhenn (neuronal 224 1 94
421574 AJ000152 Hs 105924 defensm beta 2 2 23 1 36
418005 AH 86220 Hs 83164 collagen, type XV, alpha 1 222 1 37
421948 L42583 Hs 334309 keratin 6A 220 220
407788 BE514982 Hs 38991 S100 calcium binding protein A2 219 1 61
417563 AA203701 gb zx52a10 r1 Soares.fetal.liver.εpleen. 218 240
431089 BE041395 ESTs, Weakly similar to unknown protein 216 246
447333 BE090580 Hs 70704 hypothetical protein dJ616B83 2 16 200
455797 BE091833 gb IL2-BT0731-260400 076 F04 BT0731 Homo 216 1 26
414987 AA524394 Hs 294022 hypothetical protein FLJ14950 2 16 1 99
403362 NM.001615* Homo sapienε xtm, gamma 2, 216 1 61
432374 W68815 Hs 301885 Homo εapienε cDNA FLJ11346 fiε, clone PL 2 15 211
407137 T97307 gb ye53h05 s1 Soares fetal liver splxn 215 224
402641 C1002296 gι|6677817|ref|NP_0331261| rep 2 14 2 14
418236 AW994005 Hs 337534 ESTε 214 214
413059 BE151498 gb RCO-HT0295-291199 031-E11 HT0295 Homo 2 14 2 14
432437 W07088 Hs 293685 ESTε 214 214
428398 AI249368 Hs 98558 ESTs 2 14 2 14
428336 AA503115 Hs 183752 microseminoproteiπ, beta 212 1 43
421853 AL117472 Hs 108924 SH3 domain protein 5 (ponsm) 212 1 93
436391 AJ227892 Hs 146274 ESTs 212 212
417430 AA984546 gb am88e08 s1 Stratagene schizo brain S1 211 2 17
407443 AF227138 gb Homo sapiens candidate taste receptor 2 11 236
428434 AW363590 Hs 65551 Homo sapiens, Similar to DNA segment, Ch 210 1 29
409432 D49372 Hs 54460 small inducible cytokine subfamily A (Cy 210 210
456614 AV653110 Hs 106650 hypothetical protein FLJ20533 210 200
440273 AI805392 Hs 325335 Homo sapiens cDNA FU23523 fis, clone L 210 1 37
450271 AI693900 Hs 200920 ESTs 209 234
432222 AI204995 gb an03c03 x1 Stratagene schizo brain S1 209 1 40
458208 AI380016 ESTs, Weakly similar to T4S4 HUMAN TRANS 208 200
405600 C12001673 gι|9631264|ref|NP_048045 1| or 207 1 97
434654 AI825942 Hε 139366 Homo sapiens clone L5 polyadenylated HER 207 2 52
439261 AI126020 Hs 145674 basic transcnption factor 3 205 1 45
421515 Y11339 Hs 105352 GalNAc aIpha-2, 6-sιalyltraπsferase 1, 1 204 204
457741 BE044740 gb fιm55g10 x1 NCI.CGAP.RDF1 Homo εapienε 204 204
423161 AL049227 Hs 124776 downstream of cadhenn 6 (by 33kb) 202 1 33
412505 AA974491 Hs 21734 ESTs 202 202
443180 R15875 Hs 258576 claudin 12 202 202
431605 AW972407 Hs 124370 gb EST384498 MAGE resequenceε, MAGL Homo 202 202
415938 BE383507 Hs 78921 A k ase (PRKA) anchor protein 1 202 217
452571 W31518 Hs 34665 ESTs 202 209
405061 Target Exon 201 252
439343 AF086161 Hs 114611 hypothetical protein FLJ11808 201 241
402327 Target Exon 200 244
418786 AI796317 Hs 203594 Homo sapiens uncharacteπzed gastπc pro 200 200
447343 AA256641 Hs 236894 ESTε, Highly similar to S02392 alpha 2-m 200 200
438634 AW340400 Hs 126728 ESTs 1 99 243
416127 N49843 Hs 79022 GTP-bmding protein overexpressed in εke 1 97 1 41
423961 D13666 Hs 136348 peπostιn(OSF-2os) 196 148
430397 AI924533 Hs 105607 bicarbonate transporter related protein 1 96 1 31
411010 AW813339 gb MR3-ST0192-101299 013-C05 ST0192 Homo 1 96 273
439628 W81007 Hs 58628 ESTε 1 96 1 28
444301 AK000136 Hs 10760 asponπ (LRR class 1) 1 96 1 58
431726 NM.015361 Hs 268053 KIAA0029 protein 1 95 1 72
410418 D31382 Hs 63325 transmembrane protease, seπne 4 195 1 87
452814 AI092790 Hs 334703 hypothetical protein FLJ14529 1 95 1 06
417562 AW888754 Hs 134126 crystalliπ, gamma S 1 95 2 14
424480 AA341442 Hs 205299 ESTs 1 94 1 94
404342 C7002192* gι|7299207|gb|AAF54404 1| (AE0 1 92 1 32
443320 AI051607 Hs 16335 ESTs 1 91 218
449780 AA443241 πbosomal protein L44 190 176
423337 NM.004655 Hs 127337 axm 2 (conductm, axil) 1 89 2 16
434416 AA805903 Hs 59498 cell division cycle 2-lιke 5 (cholmeste 1 89 204
457505 AL044659 Hs 43791 ESTs 1 89 2 34
425912 AL137629 Hs 162189 seππe/threoπme kmase with Dbl- and pi 1 88 1 26
413585 AH 33452 Hs 75431 fibπnogen, gamma polypeptide 1 88 1 88
428231 U17989 Hs 183105 nuclear autoantigen 1 88 1 88
428832 AA578229 Hs 324239 ESTs Moderately similar to ZN91.HUMAN Z 1 88 1 88
404429 Target Exon 1 88 2 18
447644 AW861622 Hs 108646 Homo sapiens cDNA FLJ14934 fis, clone PL 1 88 304
406641 AJ235667 gb Homo sapiens mRNA for immunoglobulin 1 86 257
417059 AL037672 Hs 81071 extrxellular matnx protein 1 1 86 1 48
454565 BE141231 gb MR0 HT0075081199003-a09 HT0075 Homo 186 1 21
415115 AA214228 Hs 127751 hypothetical protein 1 85 1 23 432306 Y18207 Hs 303090 protein phosphatase 1 , regulatory (inhib 185 145
414085 AA114016 Hs 75746 aldehyde dehydrogenase 1 family, member 184 144
403344 NM_000341 Homo sapiens solute carrier fa 184 184
447245 AK001713 Hs 17860 hypothetical protein FLJ10851 184 233
446006 NM.004403 Hs 13530 deafness autosomal dominant 5 184 202
401593 Target Exon 183 234
434392 AW983709 Hs 250824 Homo sapiens cDNA FLJ23435 fis, clone H 183 212
406461 hypothetical protein, clone 24751 183 201
455657 BE065209 gb RC1-BT0314-310300015 b12 BT0314 Homo 183 126
400609 C10001147gι|12698926|gb|AAK017391|AF33 182 208
422095 AI868872 Hs 282804 hypothetical protein FLJ22704 181 114
422867 L32137 Hs 1584 cartilage oligomeπc matnx protein (pse 181 122
417412 X16896 Hs 82112 interleukin 1 receptor, type I 181 210
426521 AF161445 Hs 170219 hypothetical protein 181 208
429610 AB024937 Hs 211092 LUNX protein, PLUNC (palate lung and nas 181 164
423915 AF039018 Hs 135281 alpha actinin 2-assocιated UM protein 180 134
439606 W79123 Hs 58561 G protein-coupled rxeptor 87 180 180
459189 AI909090 gb IL-BT198-010499007 BT198 Homo sapien 180 180
412429 AV650262 Hs 75765 GR02 oncogene 180 255
402674 Target Exon 180 341
431130 NM 006103 Hs 2719 HE4, epididymiε-spxific, whey-acidic pr 179 157
454824 AW833646 gbQV4-TT0008-161199033-d09TT0008Horno 178 194
401677 BAH -assxiated protein 3 178 228
426291 U58913 Hs 169191 εmall inducible cytokine subfamily A (Cy 178 153
430028 BE564110 Hs 227750 Target CAT 178 159
445988 BE007663 Hs 13503 inxtivatioπ escape 2 178 210
452272 AW292249 Hs 252739 hypothetical protein DKFZp434P0316 178 208
418205 L21715 Hs 83760 troponm I, skeletal, fast 178 270
400425 AY004252 Hs 287385 PR domain containing 12 177 202
400419 AF084545 Target 177 267
447169 AI989803 Hs 157289 ESTs 177 221
452359 BE167229 Hs 29206 hypothetical protein MGC14376 1 7 212
431941 AK000106 Hs 272227 Homo sapiens cDNA FLJ20099 fis, clone CO 176 254
432808 NM.015985 Hs 278973 angιopoιetιn-3 1 6 1 6
437400 AB011542 Hs 5599 EGF-like-domam, multiple 5 175 200
422487 AJ010901 Hs 198267 mucin 4, trxheobranchial 1 5 147
444986 AI204197 ESTs 175 248
451027 AW519204 Hs 40808 Homo sapiens, Similar to RIKEN cDNA 2810 174 169
413524 BE145837 gb MRO-HT0208-101299202-C07 HT0208 Homo 174 174
409099 AK000725 Hs 50579 hypothetical protein FLJ20718 174 226
405579 C22000151 gι|6806921|ref|NP_0041651| so 174 212
405797 CX001015 gι|11322384|emb|CAC166871| (AJ 173 266
405159 ENSP00000243337* CDNA FLJ13984 fis, cion 173 201
450569 AW192334 Hs 38218 ESTs 173 208
450912 AW939251 Hs 25647 v-foε FBJ munne osteosarcoma viral on∞ 1 3 124
445261 T79759 Hs 250651 ESTs, Weakly similar to I38022 hypotheti 173 252
454231 AW450669 Hs 45068 hypothetical protein DKFZp434H43 173 164
429500 X78565 Hs 289114 hexabrxhion (tenascm C, cytotxtin) 172 137
422259 AA307584 gb EST178498 Colon carcinoma (HCC) cell 172 172
456034 AW450979 gb UI-H-BI3-ala-a-12-0-UI s1 NCI.CGAP.Su 172 134
451862 H09260 Hs 32333 ESTε 171 216
403520 Target Exon 171 139
456596 AA291834 Hs 78950 branched chain keto xid dehydrogenase E 171 226
426603 AA382291 gb EST95683 Testis 1 Homo εapiens cDNA 5 170 170
418387 R18085 Hs 22279 gb yg16b12 r1 Soareε infant brain 1NIB H 170 170
433417 AA587773 Hs 8859 Homo εapieπs, Similarto RIKEN CDNA5830 170 187
402538 C1001634 gι|12621136|reflNP_0752451| Ba 169 157
414844 AA296874 Hs 77494 deoxyguaπosine kinase 169 206
418478 U38945 Hs1174 cyclm-dependent kmase inhibitor 2A (me 169 163
446553 AB021179 Hs 15299 HMBA inducible 168 202
456235 AA203637 gb zx58b12 r1 Soares jetal.liver.spleen. 168 212
424580 AA446539 Hs 339024 ESTs, Weakly similar to A46010 X-linked 168 203
433930 AA620338 ESTs 168 228
404151 Target Exon 168 180
429392 AL109712 Hs 296506 Homo sapiens mRNA full length insert cDN 167 218
430070 AF197927 Hs 231967 ALL1 fused gene from 5q31 166 216
400496 ENSP00000224716* GTP-bindmg protein SAR 166 213
413464 AL121500 ESTs 166 203
411188 BE161168 gb PMO-HT0425470100-002-a10 HT0425 Homo 166 212
446281 H69416 Hs 14606 hypothetical protein FLJ20271 165 228
443282 T47764 Hs 132917 ESTs 165 204
423217 NM 000094 Hs 1640 collagen, type VII, alpha 1 (epidermolys 165 167
453355 AW295374 Hs 31412 myopodin 165 166
432375 BE536069 Hs 2962 S100 calcium-bmdmg protein P 165 154
437929 T09353 Hs 106642 ESTε, Weakly εimilar to T09052 hypotheti 165 204
410295 AA741357 nidogen (enactin) 164 230
437767 AA830103 Hs 293331 ESTε 164 126
416580 T61572 Hs 79385 Human clone 23574 mRNA εequeπce 164 338
450795 AW173371 Hs 60435 ESTε 164 164
421847 NM.014717 Hs 108884 KIAA0390 gene product 164 275
403010 C21000152 gι|6226483|εp|Q52118|YM03_ERWS 164 203
406387 Target Exon 164 178
440423 AW293995 Hs 192277 ESTε 163 205 444381 BE387335 Hs 283713 hypothetical protein BC014245 163 207
442802 AL133035 Hs 8728 hypothetical protein DKFZp434G171 163 165
442424 AI342715 Hs 129569 ESTs, Moderately similar to B34087 hypot 162 240
402885 Target Exon 162 118
408786 AA773187 Hs 294027 ESTs 162 159
448719 AA033627 Hs 21858 tπnucleolide repeat containing 3 162 163
414684 AW630023 Hs 76893 3-hydroxybutyrate dehydrogenase (heart, 162 210
406838 AA827569 Hs153 ribosomal protein L7 161 141
441600 AA939347 Hs 127223 Homo sapiens cysteine knot prote (ZSIG 161 232
420693 NM 001972 Hs 99863 elastase 2, neutrophil 160 237
412649 NM 002206 Hs 74369 integnn, alpha 7 160 123
432331 W37862 Hs 274368 MSTP032 protein 160 123
454034 NM_000691 Hs575 aldehyde dehydrogenase 3 family, member 160 169
400279 NM 004581* Homo εapienε Rab geranylgeran 160 156
437865 AI472305 Hs 19565 ESTε 160 242
429165 AW009886 Hs 118258 prostate cancer assxiated protein 1 160 129
442993 BE018682 Hs 166196 ATPase Class I, type 8B, member 1 160 211
410684 AA088500 Hs 170298 ESTs 159 146
433149 BE257672 Hs 42949 hypothetical protein HES6 159 222
448429 D17408 Hs21223 caiponin 1, basic, smooth muscle 159 141
426457 AW894667 Hs 22660 chimeππ (chimaeπn) 1 159 126
427654 AA410183 Hs 137475 ESTs 159 283
411662 D60541 Hs 285519 Homo sapiens cDNA FLJ11904 fis clone HE 159 218
440383 AA884208 Hs 30484 ESTs 158 219
406690 M29540 Hs 220529 carcmoembryonie antigen-related cell ad 158 158
424687 J05070 Hs 151738 matrix metalloproteinase 9 (gelatinase B 158 147
407857 AI928445 Hs 92254 εynaptotagmin-like 2 158 151
411573 AB029000 Hs 70823 KIAA1077 protein 157 129
433336 AF017986 Hs 31386 εxreted frizzled related protein 2 157 117
428471 X57348 Hs 184510 εtratifin 157 155
429249 X81479 Hs 2375 egf like module containing, mucin like, 157 119
407966 AA295052 Hs 38516 Homo sapiens, clone MGC 15887, mRNA, com 157 212
418026 BE379727 Hs 83213 fatty xid binding protein 4, adipxyte 157 105
430469 AW603667 Hs 288742 Homo sapiens cDNA FLJ22712 fis, clone H 156 156
445511 AA846512 Homo εapieπs cDNA FLJ14459 fis, clone HE 155 208
404501 nucleoside phosphorylase 155 254
429107 AI470451 Hs 99075 ESTs 155 205
417259 AW903838 Hs 81800 chondroitin sulfate proteoglycan 2 (vers 155 145
429597 NM 003816 Hs 2442 a disintegnn and metalloproteinase doma 154 261
458091 AF150286 gbAF150286HumaπmRNAfromcd34stemce 154 154
439280 AI125436 Hs 123654 ESTs 154 206
428096 AW291771 Hs 42239 Homo sapiens, clone IMAGE 3868989, mRNA, 153 155
414221 AW450979 gb UI-H-BI3 ala-a-12-0-UI s1 NCI CGAP Su 153 139
451712 AA019290 Hs 110489 ESTs 153 199
402487 Target Exon 153 202
415274 AF001548 Hs 78344 myoεm, heavy polypeptide 11, smooth mus 153 129
452887 AI702223 Hs 107253 hypothetical protein DKFZp761F241 153 121
410253 T51823 ESTs 152 203
408741 M73720 Hs646 carboxypeptidase A3 (mast cell) 152 137
432985 T92363 Hs 178703 ESTs 151 148
422166 W72424 Hs 112405 S100 calcium binding protein A9 (calgran 151 115
429259 AA420450 Hs 292911 Plakophilin 151 131
429289 AI400746 Hs 62187 phosphatidylmoεitol glycan, class K 151 119
441457 AW996651 Hs 43838 ESTs 151 208
433365 AF026944 Hs 293797 ESTs 151 274
425483 AF231022 Hs 158159 FAT tumor suppressor (Drosophila) homolo 151 121
424386 BE146577 Hs 285132 ESTs 150 153
429655 U48959 Hs 211582 myosin, light polypeptide kinase 150 129
442391 AW450544 Hs 220751 ESTs 150 165
414341 D80004 Hs 75909 KIAA0182 protein 150 210
436222 AI208737 Hs 122810 Homo sapiens cDNA FLJ11489 fis, clone HE 150 216
442264 AI278777 Hs 263455 ESTs, Weakly similar to ALULHUMAN ALU S 150 150
443878 AW292499 Hs 139709 hypothetical protein FLJ 12572 150 137
430152 AB001325 Hs 234642 aquapoπn 3 150 143
447752 M73700 Hs 105938 Ixtotransferπn 149 091
404455 opioid rxeptor, kappa 1 149 136
424106 AA412442 Hε 98132 ESTs 149 130
433095 AK001092 Hs 302480 Homo εapiens cDNA FLJ10230 fis, clone HE 149 202
409361 NM.005982 Hs 54416 sine oculis homeobox (Drosophila) homolo 148 150
456256 ABO0O45O Hs 82771 vaccinia related kinase 2 148 142
439310 AF086120 Hs 102793 ESTs 148 148
407102 AA007629 glycerol 3-phoεphate dehydrogenase 1 (so 148 115
437981 AA774445 Hs 145365 ESTs, Weakly similar to KIAA1397 protein 148 236
421485 AA243499 Hs 104800 hypothetical protein FLJ10134 147 121
414799 AI752416 Hs 77326 insulin-like growth factor binding prote 147 125
453864 AW021407 Hs 21068 hypothetical protem 147 218
401067 ENSP00000252105* CDNA FLJ12240 fis, cion 147 181
456054 BE313241 gb601151545F1 NIH MGC 19 Homo sapiens c 147 199
402324 C19001982 gι|3043638|dbj|BAA254831| (AB 147 203
417733 AL048678 Hs 82503 H sapiens mRNA for 3'UTR of unknown prot 147 129
457734 BE394365 Hs 38750 hypothetical protein FLJ11526 147 226
402013 Target Exon 146 242
429295 AA682377 Hs 99216 ESTs, Moderately similar to ALU8.HUMAN A 146 209 430920 U96402 Hs 248132 goosecoid like 146 246
409368 AA071059 gb zm66a10 r1 Stratagene neuroepithelium 146 202
431958 X63629 Hs 2877 cadhenn 3 type 1, P cadhenn (placenta 146 143
427719 AI393122 Hs 134726 ESTs 146 146
433430 AI863735 ESTs 146 115
423790 BE152393 gb CM2-HT0323-171199033 a08 HT0323 Homo 146 236
444083 AI123195 gb oo17a10 x1 Soares.NSF_F8_9W_OT_PA.P_S 145 229
433256 AW604447 Hs 339408 ESTs Weakly similar to S26689 hypotheti 145 150
420859 AW468397 Hs 100000 S100 calcium binding protein A8 (calgran 145 117
456664 AW963354 Hs 334409 metallothionem 1G 145 220
438158 AI796556 Hs 187884 ESTs 145 118
409883 AW452419 Hs 296098 ESTs 145 200
452316 AA298484 Hs 61265 ESTs, Moderately similar to G786.HUMAN P 145 127
413048 M93221 Hs 75182 mannose rxeptor, C type 1 145 136
457462 AL133573 Hs 272312 Homo sapiens mRNA, cDNA DKFZp434J2235 (f 145 208
452679 Z42387 Hs 83883 transmembrane, prostate androgen induced 144 128
401116 Target Exon 144 219
419618 AA528295 gb nh26e06 s1 NCI_CGAP_Pr3 Homo εapiens 144 230
452281 T93500 Hs 28792 Homo sapiens cDNA FLJ11041 fis, clone PL 144 203
426125 X87241 Hs 166994 FAT tumor suppressor (Drosophila) homolo 1 3 148
428330 L22524 Hs 2256 matnx metalloprotemase 7 (matπlysin, 143 151
418742 AW451197 Hs 113418 ESTs 143 124
418335 R63267 Hs 28399 ESTs 143 114
408404 AW192518 gb l45h08 1 NCI_CGAP_Pan1 Homo sapiens 143 208
448175 BE296174 Hs 225160 hypothetical protein FLJ13Ϊ02 143 229
431846 BE019924 Hs 271580 uroplakin 1B 143 212
459557 N58315 gb yv68g06 s1 Soares fetal liver spleen 143 200
449925 AI342493 Hs 24192 Homo sapiens cDNA FLJ20767 fis clone CO 143 133
442321 AF207664 Hs8230 a disintegnn like and metalloprotease ( 143 110
454843 AW834536 Hs 258549 gb MR2-TT0014-241199012 f06TT0014 Homo 1 3 155
410281 AF076612 Hs 166186 Homo sapiens clone 23928 mRNA sequence 143 138
402998 NM 002463* Homo εapiens myxovirus (influ 1 2 216
443709 AI082692 Hs 134662 ESTs 142 222
435259 AA152106 Hs4859 cyclin L ania 6a 142 201
454407 AW578420 Hs 118843 gb RC1-CT0249-120100022 b04 CT0249 Homo 142 176
453359 AA448787 Hs 24872 ESTs 142 133
434126 AI138589 Hs 118205 ESTs 141 206
417944 AU077196 Hs 82985 collagen, type V, alpha 2 141 146
442316 Z75331 Hs 8217 stromal antigen 2 141 220
438330 AW450572 Hs 257316 ESTs 141 220
410935 BE067395 Hs 66881 dynein cytoplasmic intermediate polype 141 202
455885 BE153524 gb PMO HT0339241199-002-003 HT0339 Homo 141 133
405550 C7001981* gι|565157|gb|AAB318811| T-cel 141 124
451385 AA017656 gb ze39h01 r1 Soares retina N2b4HR Homo 141 199
424925 NM 002432 Hs 153837 myeloid cell nuclear differentiation ant 140 264
431022 AA490815 Hs 208351 ESTs 140 126
439781 AA845538 glial cells misεing (Drosophila) homolog 140 272
429379 NM 014840 Hs 200598 KIAA0537 gene product 140 105
435310 AA705075 Hs 169536 Rheεus blood graup-assxiated glycoprote 140 126
430702 U56979 Hs 278568 H fxtor 1 (complement) 139 118
451331 AK002039 Homo sapienε cDNA FU 11177 fiε, clone PL 139 126
459198 AI086347 Hs 151138 ESTε 139 122
442344 AI022925 Hs 79368 epithelial membrane protein 1 139 135
402917 ENSP00000202587* Bicarbonate transporter 139 144
418211 BE244746 Hs 247474 hypothetical protein FLJ21032 139 208
437158 AW090198 KIAA1150 protein 138 207
427373 AB007972 Hs 130760 myosin phosphatase, target subunit 2 138 124
433911 A1923092 Hs8899 ESTs 138 215
402504 C1003823* gι|4826521|emb|CAB428531| (AL 138 138
409465 AW393810 Hε 78054 gb QV4-TT0008-251099016-e11 TT0008 Homo 137 222
449426 T92251 Hs 198882 ESTs 137 238
405491 Target Exon 137 274
406685 M18728 gb Human nonspxific crosεrextmg antig 137 134
442410 AW886503 Hs 197680 ESTs 137 156
407701 AW375009 Hs 164407 ESTs 136 202
400818 Target Exon 136 210
406475 C15000508* gι|2558825|gb|AAC533871| (AF 136 278
426935 NM.000088 Hs 172928 collagen, type I, alpha 1 136 141
414171 AA360328 Hs865 RAP1 A, member of RAS oncogene family 136 220
444195 AB002351 Hs 10587 KIAA0353 protein 135 094
447918 AI129320 Hs 115175 ESTs, Highly similar to JC5818 gamma-xt 135 122
421314 BE440002 Hs 180324 Homo sapiens, clone IMAGE 4183312, mRNA, 135 140
412992 AI423369 HS75111 protease, senne, 11 (IGF binding) 135 124
401025 NM.004055* Homo sapienε calpam 5 (CAPN5 135 130
452862 AW378065 Hε8687 ADAMTS2 (a disintegnn like and metallo 134 212
425308 M97639 Hs 155585 rxeptor tyrosine kinase like orphan rec 134 102
402308 Target Exon 134 121
428415 AA337211 Hs 184222 Down syndrome cπtical region gene 1 134 140
407242 M18728 gb Human nonspecific crossrexting antig 134 122
410741 Z11695 Hs 324473 mitogen activated protein kinase 1 134 205
439335 AA742697 Hs 62492 NM.052863 Homo sapiens secretoglobm fa 134 112
431254 NM 006069 Hs 251385 munne retrovirus integration site 1 hom 133 121
405213 Target Exon 133 203 447990 BE048821 Hs 20144 small inducible cytokine εubfamily A (Cy 133 105
421535 AB002359 Hs 105478 phosphonbosylformylglycinamidinesyntha 133 209
453914 NM 000507 Hs574 fructose-1,6 bisphosphatase 1 133 132
443604 C03577 Hs9615 myosin regulatory light chain 2, smooth 133 118
430385 AA113437 N myc downstream regulated gene 3 132 148
447731 AA373527 Hs 19385 CGI-58 protein 132 222
400740 hypothetical protein FLJ 14280 132 201
410481 R34107 Hs 321450 pregnancy specific beta-1-glycoprotem 2 132 132
440274 R24595 Hs7122 scrapie responsive protein 1 132 132
406867 AA157857 Hs 182265 keratin 19 132 142
456855 AF035528 Hs 153863 MAD (mothers against decapentaplegic, Dr 132 230
443144 BE246335 hypothetical protein MGC14797 132 203
432810 AA863400 ESTs 132 401
445537 AJ245671 Hε 12844 EGF-like domain, multiple 6 131 124
424075 AI807320 Hs 227630 RE1-sιleπcιng transcription fxtor 131 217
440099 AL080058 Hs 6909 DKFZP564G202 protein 131 153
428957 NM.003881 Hs 194679 WNT1 inducible signaling pathway protein 131 131
438874 H02780 gb yj41a11 r1 Soares placenta Nb2HP Homo 131 203
402825 Target Exon 131 124
422737 M26939 Hs 119571 collagen, type III, alpha 1 (Ehlers-Danl 131 145
423225 AA852604 Hs 125359 Thy-1 cell surface antigen 131 119
417640 D30857 Hs 82353 protein C receptor, endothelial (EPCR) 131 112
436027 AI864053 Hs 39972 ESTs, Weakly similar to I38588 reverse t 130 206
407409 AF060168 gb Homo εapiens AS10 protein mRNA, parti 130 216
400221 NM_002082* Homo εapiens G protein-couple 130 202
437751 AA767373 ESTs, Moderately similar to ALU1.HUMAN A 130 244
450008 H52970 Hs 36688 WAP four-disulfide core domain 1 130 119
441591 AF055992 Hs183 Duffy blood group 129 103
405973 Target Exon 129 132
424604 AW865388 Hs 151076 KIAA1243 protein 129 092
410899 AW809716 gb MR4-ST0124-241199026-h09 ST0124 Homo 129 206
405818 CX001073 gι|4176497|emb|CAA201161| (AL0 129 205
402621 Target Exon 129 306
436469 AK001455 Hs5198 Down syndrome critical region gene 2 128 235
431890 X17033 Hs 271986 integnn, alpha 2 (CD49B, alpha 2 subuni 128 144
453331 AI240665 ESTs 128 236
439791 H77774 Hs 35755 ESTs 128 200
431385 SE178536 Hs 11090 membrane spanning 4-domaιπs, subfamily A 128 300
407266 AJ235664 gb Homo sapienε mRNA for immunoglobulin 128 128
446526 H89616 Homo sapiens cDNA FLJ13357 fis, clone PL 128 128
455577 BE006341 gb RC2-BN0127-240300-011-b05 BN0127 Homo 128 128
418863 AL135743 Hs 25566 ESTs, Weakly similar to 2004399A chromos 128 210
407711 AI085846 Hs 25522 KIAA1808 protein 128 123
417043 NM 004369 Hs 80988 collagen, type VI, alpha 3 128 119
420136 AW801090 Hs 195851 xtm, alpha 2, smooth muscle aorta 127 124
418203 X54942 Hs 83758 CDC28 protein kinaεe 2 127 208
448515 H68441 Hs 13528 hypothetical protein FU14054 127 205
444418 AL034417 Hs 11169 Gene 33/Mιg-6 127 198
427809 M26380 Hs 180878 lipoprotein lipase 127 109
414690 BE410103 Hs 12313 hypothetical protein FU 14566 127 136
439919 AA970710 Hs 128064 ESTs 127 228
401311 Target Exon 127 205
444235 AW207346 Hs 143202 ESTs 127 200
430858 AF007190 Homo sapiens SIB 297 intestinal mucin (M 126 123
448186 AA262105 Hs4094 Homo sapiens cDNA FU14208 fis, clone NT 126 240
400161 Eos Control 126 133
444239 R57988 Hs 10706 epithelial protein lost in neoplasm beta 126 120
438369 T77886 Hs 83428 nuclear fxtor of kappa light polypeptid 126 126
441944 AW855861 Hs8025 Homo sapiens clone 23767 and 23782 mRNA 126 112
431142 AA852596 Hs 250641 tropomyosin 4 126 123
434229 R56378 Hs 181223 hypothetical protein PRO2801 126 204
406733 AA976565 Hs 297753 vimentin 126 129
422292 AI815733 Hs 114360 transforming growth fxtor beta-stimulat 125 116
424137 AA335769 Hs 16262 ESTε 125 127
434868 R50032 Hs 159263 collagen, type VI, alpha 2 124 150
424408 AI754813 Hs 146428 collagen, type V, alpha 1 124 129
433750 H15448 Hs 31330 Homo εapienε clone HQ0319 124 127
447299 AF043897 Hs 18075 chromosome 9 open reading frame 3 124 113
438357 AI042101 Hs 294107 ESTs 124 204
409959 BE349470 mucin 6, gastπc 123 222
439897 NM.015310 Hε 6763 KIAA0942 protein 123 244
421982 AF206019 Hs 110347 REV1 (yeast homolog)- like 123 214
407207 T03651 Hs 336780 tubulm, beta polypeptide 123 132
416956 AA810664 Hs 101660 hypothetical protein MGC5391 123 239
413624 BE177019 Hs 75445 SPARC-like 1 (mast9, heviπ) 123 106
442941 AU076728 Hs 8867 cysteine-πch, angiogenic mducer, 61 123 151
452304 AA025386 Hs 61311 ESTs, Weakly similar to S10590 cysteine 123 101
414359 M62194 Hs 75929 cadhenn 11 , type 2, OB-cadheπn (osteob 122 141
452934 AA581322 Hs 4213 hypothetical protein MGC16207 122 117
421341 AJ243212 deleted in malignant brain tumors 1 122 109
406850 AI624300 Hs 172928 collagen, type I, alpha 1 122 152
452167 N75238 Hs 13075 Homo εapiens cDNA FLJ23013 fis, clone L 122 255
423189 M59371 Hs 171596 EphA2 122 115 401899 Target Exon 122 122
403579 Target Exon 122 234
415954 AA171850 Hs 42251 ESTs 122 224
429171 AI743173 Hs 169095 ESTs Weakly similar to ARL2 HUMAN ADP-R 121 114
444071 AI627808 Hs 110524 ESTs 121 223
424344 AF036973 Hs 145477 HCGIV 6 protein 121 215
434051 AF116622 gb Homo sapiens clone FLB4217 mRNA seque 121 125
422311 AF073515 Hε 114948 cytokine rxeptor like factor 1 121 139
404600 Target Exon 121 129
429751 M55210 Hε 214982 laminin, gamma 1 (formerly LAMB2) 121 103
430392 NM 000627 Hε 241257 latent transforming growth factor beta b 121 121
422687 AW068823 Hs 119206 insulin like growth factor binding prote 121 123
424855 AW204725 Hs 25560 ESTs 120 198
418890 AA232134 Hs 190028 ESTs 120 133
413232 BE073258 Hs 133988 hypothetical protein FKSG28 120 218
414154 AW205314 Hs 323060 ESTs 120 134
416784 AA334592 Hs 79914 lumican 120 127
410933 C15974 gb C15974 Clontxh human aorta polyA mRN 119 205
415388 AF018081 Hs 78409 collagen, type XVIII, alpha 1 119 111
406731 AI559131 gbtq31g07x1 NCI CGAP Ut1 Homo sapiens 119 119
447563 BE536115 Hs 160983 EST 119 114
405531 Target Exon 119 202
400363 NM 001403 eukaryotic translation elongation factor 119 121
426611 BE178050 Hs 171271 catenin (cadheπn-ass∞iated protein), b 119 118
427676 AA394062 Hs 300772 tropomyosin 2 (beta) 118 116
413929 BE501689 Hs 75617 collagen, type IV, alpha 2 118 120
413856 D13639 Hs 75586 cyclin D2 118 120
427111 AA351026 Hs 173594 serine (or cyεteine) proteinase inhibito 118 112
422287 F16365 Hs 114346 cytxhrome c oxidase subunit Vila polype 118 105
412758 Y07818 Hs 74566 dihydropyπmidinase-like 3(ULIP) 118 106
446868 AV660737 ESTs 118 118
417613 AV654351 Hs 82306 destπn (actin depolymerizing fxtor) 118 117
405542 Target Exon 118 198
419908 AW971327 Hs 293315 ESTs 117 202
434095 AA011117 Hs 3745 milk fat globule EGF factor 8 protein 117 119
407230 AA157857 Hε 182265 keratin 19 117 135
448413 AI745379 Hε 42911 ESTs 117 287
426653 AA530892 Hs 171695 dual specificity phosphatase 1 117 139
424572 M19650 Hε 179600 2,3-cyclιc nucleotide 3' phoεphodieste 117 208
440109 AK001138 Hs 333149 hypothetical protein FLJ10276 117 106
405131 C1002509 gι|9938010|ref|NP_0646841| odo 117 222
422354 U20982 Hε 1516 insulin like growth factor-binding prote 117 119
442124 R66412 Hε 129013 Homo sapiens cDNA FLJ14309 fis, clone PL 117 111
400080 Eos Control 116 253
431924 AK000850 Hε 272203 Homo sapiens cDNA FLJ20843 fis, clone AD 116 200
412802 U41518 Hs 74602 aquapoπn 1 (channel forming integral pr 116 130
429207 AA447941 Hs 123423 ESTs 116 127
415149 X12451 Hs 78056 cathepsin L 116 112
400231 Eos Control 116 117
416653 AA768553 Hs 193145 metallothioπein 1E (functional) 116 116
422813 AV656571 Hs 121068 transmembrane 4 superfamily member 6 116 110
439318 AW837046 Hs6527 G protein-coupled rxeptor 56 116 115
422424 AI186431 Hs 296638 prostate differentiation fxtor 116 121
432745 AI821926 gb πt78f05 x5 NCI_CGAP_Pr3 Homo sapieπε 115 200
412477 AA150864 microsomal glutathione S-transferase 1 115 123
430361 AI033965 Hs 239926 steral C4-methyl oxidase-like 115 231
424512 X53002 Hs 149846 integπn, beta 5 115 115
449924 W30681 Hs 146233 Homo sapiens cDNA FU22130 fis, clone H 115 124
414682 AL021154 Hs 76884 inhibitor of DNA binding 3, dominant neg 115 107
456076 BE243877 ATPase, Na? transporting, beta 3 polypep 115 200
403026 Target Exon 115 232
422545 X02761 Hε 287820 fibraπxtm 1 115 117
412719 AW016610 Hε816 ESTs 115 105
421848 X15880 Hs 108885 collagen, type VI, alpha 1 115 114
422087 X58968 Hs 111301 matnx metalloproteinase 2 (gelatmase A 115 116
413936 AF113676 Hs 297681 serine (or cysteine) proteinase inhibito 114 113
449845 AW971183 Hs6019 DnaJ (Hsp40) homolog, subfamily C, membe 114 207
430202 T85775 gb yd60g02 r1 Soares fetal liver εpleen 114 114
418806 AA485970 Hε 191718 ESTs 114 214
424017 AA333789 gb EST37925 Embryo, 9 week Homo sapiens 114 216
422003 AA361760 Hs 296326 ESTs 114 117
437272 AW975957 gb EST388066 MAGE resequences, MAGN Homo 114 217
438367 N79688 Hs 204354 ras homolog gene family, member B 114 123
453152 AK001933 Hs 31945 hypothetical protein FU11071 113 Z36
406849 AA454809 Hs 172928 collagen, type I, alpha 1 113 133
422110 AI376736 Hs 111779 secreted protein, acidic, cysteine πch 113 106
425335 BE394327 Hs 296267 follistatin like 1 113 108
434795 BE620794 Hs4147 translocating chain assxiating membrane 113 108
417426 NM 002291 Hε 82124 laminin, beta 1 113 111
452924 AW580939 Hs 97199 complement component C1q rxeptor 113 101
416379 N38857 Hs 34145 ESTs 112 112
421464 AA291553 Hs 190086 ESTs 112 201
442420 AI024834 Hs 131729 ESTε 112 )5 405369 NM.005569* Homo sapienε LIM domain kinas 112 199
421730 AW449808 Hs 334534 glucosamine (N xetyl) 6-sulfatase (Saπf 112 208
405932 C15000305 gι|3806122|gb|AAC691981| (AFO 111 201
453542 AW836724 Homo sapienε mRNA expreεsed only in plac 111 200
437585 AW976857 ESTs 111 201
412524 AA417813 Hs 44208 hypothetical protein FLJ23153 111 105
449931 AW875786 Hs 25734 ESTs, Weakly similarto BING1 [H sapiens 111 103
407085 Z70759 gb H sapiens mitochondnal 16S rRNA gene 110 112
447191 NM 014521 Hs 17667 SH3 domain binding protein 4 110 104
406713 U02629 Hs 77385 myosin, light polypeptide 6, alkali, smo 110 107
432675 AI791855 Hs 105884 ESTs 110 230
432731 R31178 Hs 287820 fibroπxtiπ 1 109 212
430763 AA485468 DNA fragmentation factor, 45 kD, alpha p 109 210
438855 AW946276 Hs6441 Homo sapiens mRNA, cDNA DKFZp586J021 (fr 109 104
405156 NM 003213* Homo sapiens TEA domain famil 109 219
409031 AA376836 ESTs 109 2.22
422608 AW160644 Hs 118695 potassium voltage-gated channel, subfami 109 226
440704 M69241 Hs162 insulin like growth factor binding prote 109 128
410577 X91911 Hs 64639 glioma pathogeπesis related protein 108 264
414191 AW250089 Hs 75807 PDZ and LIM domain 1 (elfin) 107 102
452219 AA024860 Hs 61224 ESTs 107 208
430108 AA465294 ESTs 107 211
402174 Target Exon 107 211
416952 AI767736 Hs 290070 gelsolm (amyloidosis, Finnish type) 107 100
410199 AW377424 Hs 205126 Homo sapiens cDNA FLJ22667 fis, clone H 107 113
442670 BE410050 Hs 11859 hypothetical protein FLJ13188 107 221
442310 AF033199 Hs8198 zinc finger protein 204 106 204
405536 NM.005805 Homo sapiens 26S proteasome as 106 220
424736 AF230877 Hs 152701 microtubule interxting protein that ass 106 106
423017 AW178761 Hs 227948 serine (or cysteine) proteinase inhibito 106 106
425371 D49441 Hs 155981 mesothelin 106 127
429925 NM 000786 Hs 226213 cytxhrome P450, 51 (laπosterol 14-alpha 106 237
406711 N25514 Hs 77385 myosin, light polypeptide 6, alkali smo 106 105
409407 AW967370 Hs 342655 Homo sapienε cDNA FLJ13289 fis, clone OV 105 200
406109 Target Exon 105 204
418597 AK001678 Hs 86337 similar to DNA-directed RNA polymerase I 105 267
403162 C2000231* gι|9802031|gb|AAF995971|AF239 105 207
411020 NM 006770 Hs 67726 mxrophage rxeptor with collageπouε str 105 107
407225 J04617 eukaryotic translation elongation fxtor 105 102
416955 AW889150 Hs 80595 NM_004552* Homo εapieπs NADH dehydrogena 105 110
451989 AF169797 Hs 27413 adaptor protein containing pH domain, PT 104 212
410276 AI554545 angιopoιetιn-2 104 104
446921 AB012113 Hε 16530 small inducible cytokine subfamily A (Cy 104 104
406712 M31212 Hs 77385 myosin, light polypeptide 6, alkali, smo 103 105
406773 AA812424 Hs 76067 heat shxk 27kD protein 1 103 110
452082 N51905 Hs 125133 hypothetical protein FLJ22501 103 201
419150 T29618 Hs 89640 TEK tyrosine kinase, endothelial (venous 103 224
417204 N81037 Hs 1074 surfxtant, pulmonary-assxiated protein 102 100
408339 R97502 Hs 30443 sentπn/SUMO-spxific protease 102 219
400247 Eos Control 102 204
430030 BE300094 Hs 227751 Ixtin, galxtoside-bindmg, soluble, 1 101 101
442275 AW449467 Hs 54795 ESTs 101 104
406786 AW161678 Hs 111334 ferπtin, light polypepbde 101 106
439403 BE265745 ESTs, Weakly similar to ALUC_HUMAN tm 101 211
428043 T92248 Hs2240 uteroglobin 100 106
406722 H27498 Hs 293441 Homo sapiens SNC73 protein (SNC73) mRNA, 100 102
432242 AW022715 Hs 162160 ESTs, Weakly similar to ALU4_HUMAN ALU S 100 216
450724 R55428 gb yj79b05 r1 Soares breast 2NbHBst Homo 100 099
424125 M31669 Hs 1735 inhibin, beta B (activin AB beta polypep 100 108
432077 AL134685 gb DKFZp547M126_r1547 (εynonym hfbrl) 100 205
427687 AW003867 Hs 1570 histamine rxeptor H1 100 100
435256 AF193766 Hs 13872 cytokine-like protein C17 100 100
420026 AI831190 Hs 166676 ESTs 100 100
455128 AW861555 Hs 314372 EST 100 100
410685 AA497117 Hs 58893 ESTs, Moderately similar to ALULHUMAN A 100 100
401404 Target Exon 100 100
449625 NM 014253 odz (odd Ozteπ m, Droεophila) homolog 1 100 100
443458 R05385 Hs 143509 hypothetical protein FU21924 100 100
452744 AI267652 Hs 246107 Homo εapiens mRNA, cDNA DKFZp434E082 (fr 100 100
418355 L42563 Hε1165 ATPase, H? transporting, nongastπc, alp 100 100
447947 N33033 Hs 270215 ESTs 100 100
419236 AA330447 Hs 135159 Homo sapienε cDNA FU11481 fis, clone HE 100 100
455047 AW852530 gb PM1-CT0243-071099-001 -g06 CT0243 Homo 100 100
440400 AA994364 Hs 125594 ESTs, Weakly similar to T25472 hypotheti 100 100
444963 AI916973 Hs 213603 ESTs 100 100
410934 AW811114 gb MR2-ST0131-111199016-a04ST0131 Homo 100 100
442849 R10099 Hε 269805 ESTs 100 100
420407 AA814732 Hs 145010 lipopolysaccaπde εpxific reεponse 5-lι 100 100
454600 AW810001 gb MR4-ST0124-270300-005-b11 ST0124 Homo 100 100
418454 AA315308 Hs 195870 hypothetical protein FU 14991 100 100
459045 N69101 Hs 40730 ESTs 100 100
455500 AW963582 gb EST375655 MAGE resequences, MAGH Homo 100 100
411745 AW867826 gb MR0 SN0039300300001-c02 SN0039 Homo 100 100 429932 AI095005 Hs 21586 ESTs 1 00 100
432365 AK001106 Hs 274419 hypothetical protein FLJ10244 1 00 1 00
415817 U88967 Hs 78867 protein tyrosine phosphatase receptor-t 1 00 1 00
431374 BE258532 Hs 251871 CTP synthase 1 00 1 00
443162 T49951 Hs 9029 DKFZP434G032 protein 1 00 1 00
432128 AA127221 Hs 296502 ESTs 099 233
451838 AW005866 Hs 193969 ESTs 0 98 326
438414 AA806794 Hs 131511 ESTs 097 361
435872 AA701357 Hs 192759 ESTs 0 97 096
425211 M18667 Hs 1867 progastπcsin (pepsinogeπ C) 097 1 08
424001 W67883 Hs 137476 paternally expresεed 10 0 96 225
418869 AW516565 gb xq01d05 x1 Soareε NHCeC_cervιcal_tumo 096 207
458659 AW749895 Hs 332520 Homo εapienε mRNA, cDNA DKFZp434A1014 (f 0 94 218
418458 AA332941 Hs 85226 lipaεe A, lysosomal acid, cholesterol es 094 1 31
432728 NM 006979 Hs 278721 HLA claεε II region expreεεed gene KE4 094 212
432093 H28383 gb yl52c03 r1 Soares breast 3NbHBst Homo 094 219
452239 AW379378 protein tyrosine phosphatase, receptor t 094 079
403167 Target Exon 094 206
402209 Target Exon 092 204
453500 AI478427 Hs 43125 esophageal cancer related gene 4 protein 092 074
424090 X99699 Hs 139262 XIAP associated factor-1 091 211
432816 N38913 Hs 221575 ESTs 0 91 215
451779 AW968616 Hs 296234 ESTs, Weakly similar to T31613 hypotheti 0 91 214
406851 AA609784 major histocompalibility complex, clasε 089 104
427698 AW972594 Hs 335499 ESTs 0 89 090
440006 AK000517 Hs 6844 NALP2 protein, PYRIN Containing APAF1-lι 088 242
427383 NM 005411 Hs 177582 surfactant, pulmonary associated protein 0 87 1 14
426024 Z43405 Hs 75668 Homo sapiens, Similar to RIKEN cDNA 1700 087 204
400986 NM.024085* Homo sapienε hypothetical pro 0 87 210
430353 AW952337 citrate synthase 086 228
404975 uncharxteπzed hypothalamus protein HT0 0 86 250
406673 M34996 Hs 198253 major histxompatibility complex class 086 1 94
431323 AW970623 gb EST382705 MAGE resequences, MAGK Homo 080 208
404926 Target Exon 079 201
432297 AW663632 Hs 285625 Homo sapienε mRNA cDNA DKFZp434A119 (fr 077 086
437601 AA761546 Hs 248844 ESTε, Weakly similar to ALU1.HUMAN ALU S 077 2 10
421566 NM 000399 Hs 1395 early growth response 2 (Krox-20 (Drosop 076 266
406646 M33600 Hs 308026 major histxompatibility complex, claεε 076 1 09
442195 NM 001430 endothelial PAS domain protein 1 076 200
415457 AW081710 Hs 7369 ESTs, Weakly similar to ALULHUMAN ALU S 0 76 078
413916 N49813 Hs 75615 apolipoproteiπ C-ll 073 206
453716 AA037675 Hs 152675 ESTs 073 210
437802 A1475995 Hs 122910 ESTs 070 208
422282 AF019225 Hs 114309 apolipopratem L 068 295
410361 BE391804 Hs 62661 guanylate binding protein 1, interferon- 0 54 2 11
424917 AI636208 Hs 96901 hypothetical protein FLJ23049 053 053
TABLE 34B
Pkey Unique Eoε probeεet identifier number
CAT number Gene cluster number Accesεion Genbank xceεsion numbers
Pkey CAT Number Accesεion
442006 1239046.1 AW975183 AA973583 AI365103 AI699495 AI301787 420195 28714.1 AK002039 AL117524AV714494AW954901 AL045243 BF955185 AU137860 AW880615AW880496AA256290 BE767078 N44348 AI886676
AA455877 N66571 AA999864 AU157344 AI817146 R54821 BE223107 AA455880 AI355752 BF589210 N63487 AI924033 AI923020 AI306145
A1919421 AI584169 AI250173 AI440227 AA669696 AW244040 A1358104 A1570333 AI418315 N94787 R72348 N94780 BF944396 BF754698
AW005707 N98831 BF001047 BF588691 AA318076 AW601474 AW883910 H10056 N63481 BE838574 BF909132 BI084973 BG257295 BG818471
BE348449 AI420623 AW271213 BE048764 W44682 AI887849 AW903942 AA975919 AA312915 BF948057 R55120 H10110 BI045196 AW880645
437620 9575.20 AW976930 AW292808 AW451796 BF514112 AI806378 AI658903 AI769457 AW593455 AI625525 AI538551 AI660509 AA761825 AA973287
AA861483 W73065 AI735361 W60499 W76653 BG959557
430712 301999 1 AW044647 AI670953 AI656180 AA484715 AI659205 BF923472 411880 1139083.1 BE088101 T05990AW872477 451149 4941 2 AF231512 A 300273 BG779015 AW510935 AI989816 AA137069 AI748876 AW150861 AI862628 AI805872 AI675382 BE855437 A 044703
AI677769 AA886718 AI753144 AA626885 AI018092 AI263010 AW026173 BE221138 AA256268 AW571932 AW276137 AI634216 AW296259
AA977716 AI302589 AA348340 AI720838 AI311733 AA015867 N73713 AL047586 AW840354 AA256196 AW840357 AW840504 T35664 Z36755
AW954421 AA247424 AIO56930 T31380 BI910428 H88489 BG675223 AA443427 BE879501 AA478530 R72977 AA298568 BF792417 AA356982
BF922499 BE764808 BE565636 BF903986 BF331881 N42207 BG623760 BG611090 BF735387 BE697757 BE697755 BE718853 N78560 AI984095
AA137140 AA053711 N59865 AI078134 AA643796 T57803 AA018642 N66799 AI004600 BG896323 BF895104 N73684 N73806 N73811 AW900287
AA018641
459702 539529 1 BG207209 BE166299 AI204995 BG199355 AW969908 AA528756 AW440776 BI044354
417563 2243443 1 AA203701 R86895
431089 125941.2 BG940189 AW063489AA715980 BF001091 BF880066 AA666102AA621946 AA491826
455797 1511159 1 BE091833 BE091874 BE091871
413059 1488711 1 BE063078 BE151503 BE151498
417430 40161 2 AW872732AW827432 AA199662 AA610519 R54983
432222 539529 1 BG207209 BE166299 AI204995 BG199355 AW969908 AA528756 AW440776 BI044354
458208 45807 4 AI990640 AI380016 BM273298 BM273060
457741 120741 1 BI017968 BE044740 BI017768 AW827360 BF380597 BI017970 BF746974 BF380582 BF380592 BF908552 BF907924 BF380784 BF380651
BF380634 BE166581 BE161439 BF908606 BI017961 BE044718 AW827623 BF907758 BI017967 AW827621 AA653908 BI017765 BI017955
BI017960 BI017798 411010 1066474.1 AW813381 AW816094AW813357 AW814469 AW813293 AW816099 AW813295 AW813425 AW813331 AW813325AW813351 AW813427
AW813339 449780 31099.2 BG721806 BG623574 AA367501 BG436403 BG619828 BG570704 BF086115 BF086118 R78932 BG620860 BG571920 BF997723 AA368244
BG620631 BG621967 BG435818 BG620442 BG621518 H12650 BG573175 H61600 R67484 H01715 D78811 BG435953 BF107266 D79043 R67255
H01310 BG570941 BG570693 R21776 AA327133 R32578 R30775 BG570963 T86946 H61601 W86279 BF991104 R21732 BF990905 BG622861
BE929694 AI090290 BE929277 BE929284 AA367783 AA082581 D78839 H78318 N91085 BE929344 D63217 BE929334 H53536 R80360 H54070
C17064 AW962470 R00900 BG619698 BG623946 H94918 BE929345 AA004267 BF957177 BG620685 BF086421 T87029 C17044 H60972
BG573514 AA131924 D78838 BG003560 C18615 W86323 R09737 R02529 AA367502
406641 00 AJ235667 AJ235668 AJ235669 AJ235670
454565 1061836.1 BE141160 BE141231 BE141793 BE141791 BE141167 BE141807 BE141806 BE141805 AW807591 AW807590 AW807586 AW807583 BE141803
A 845918 BE141207 BE141158
455657 14901851 BE065209 BE065364 BE065110 BE065111
459189 MH19455 AV683451 AK057494 BG718853 BM152866 BG390826 BE709644 AI864727 BI045181 BI459637 AI909102 AI909Q90 BG722507 BI023834
454824 10736551 AW833783 AW833646 AW833525 AW833351 AW833526 AW833825
444986 7047331 AW268472 AI204197 AW592537
413524 15188591 BE145894 BE145837 BM263472
422259 140437.1 BF821471 AW795791 BF844843 BF821371 AA307584 AW795790 BF833724 BE154067 BE064709
456034 6855861 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
426603 12991621 AA994657 AA382291
456235 19797641 AA203637AA832266 H67452
433930 19851.15 AW873618 AA620338
413464 4155321 AL527514 AI732432 AA133309 A1225224 AV700997 BF589361 AW291763 AL121500 AA129708
411188 1072487.1 AW821260 BE162466 BE161168
410295 28171 BG402852 BG545066 AA150252 AL036760 AA452480 AI033256 W68776 W93372 N31248 AI052219 AI367635 W69374 N88610 R58194 BI524854
81497111 BF940043 AI129268 AI359798 AI056480 AA121421 AI042150 AW449003 AI418180 AI419420 AI356058 BF832243 AI349330 AI359448
W76647 BF477170 AA099163 BF994549 AW608256 AA045418 H03770 AL574791 AW069455 BE302148 AW022281 AW960273 AA121268
AI336371 A1989381 AI131425 A1147483 AI311537 AW338638 AI141649 AA709414 AI187177 AA780884 AI333805 AA045312 A1623918 AI349421
W63753 W70299 AA557276 AA299007 N98212 W74064 N24823 T54892 AA054724 W73059 AI869152 N93462 N71889 AI537432 R71628
AA303089 AI498550 T60941 AV706417 AW067848 AI150677 AW338118 AI336313 AA826256 AI139518 AA662948 AA902723 AI970175 W68682
AI089380 AI148372 H99951 AW183001 AI270317 AA532767 AA044727 AA931652 R82469 AA150261 W67788 H67495 R80715 AW149812 N78914
AI862034 W61122 AW023118 W69375 T88917 T47984 N21531 R35646 AA055544 H15534 AA688295 AA090586 AA044764 BF994641 R79547
N21313 BF674610 H02874 AW975323 R16904 AA328030 AA054671 R79546 BF832310 A1249109
400279 2140.1 Y08200 NM.004581 BC003093 BE733834 BI753321 BG773890 BF091906 BI917541 AI023762 AA587230 BF435086 AI264262 AI687392 AI810536
AW589886 AI244419 AA749261 AA535435 AW205689 AI765770 AI765431 C02465 AW305347 AI818456 AA322111 AW381845 AW381829
AV749407 AA811636 AU159893 AA603065 AA652542 AI468678 R49616 AW381863 BE389867 BE182387 BF087771 AA527551 AA134051
AA831504 AA134052 AI871759 AW089048 BI913532 AA367709 BG828155 BF093014
445511 9560.8 BM471219 BE093160 BG171761 B1254009 A1905474 AA453162 AA829759 A1086559 AA776022 A1377446 BF589018 AA452822 AW614566
AA443880 AA476733 AW970674 AI393291 AA988283 AI905528 AW384956 D78656
458091 4526941 AF150286 AV739062 AA835857
414221 6855861 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945
410253 132134.1 AA774785 AA584875 AA577705 AA683178 AA083204 AW362057 T92332 T51823 T02858 AA083375 T92381
407102 7177.2 AW945170 BF930905 F33652 BG057818 AI368018 A1421485 AI300352 A1378525 AI264177 AI276281 AI245302 AI281050 AI190036 AW451438
AW242903 AA910870 F22289 F19647 F22375 AW473816 BF445785 AA774528 F33447 C01077 AW772227 F17759 H42812 R09701 AA349096
R48772 H42892 H42537 R47898 N28263 H25721 F32386 H43971 R48205 F21390 H45809 AA007629 R47897 R83734 H45844 AW983653 H43970
H42536 H24495 R48875 H42961 H22079 R86018
456054 12635701 BF314481 BE313241 BI196333 BE383148
409368 1106121 AA071059 AA085201 AA085020
433430 2181751.1 AA961586 AI863735 AA588325
423790 8863441 BE152393 AA330984 BE073904 BF176271
444083 1090812 BI836699AI123195
419618 252691.1 BG168298 AA247945 AA528295 AW971284
408404 6584751 BF3Q8B98 BE298629 BE298765 AW192518 BE299614 BE300025 BF307463
459557 8597941 BG623239 N58315 A1524952
455885 15245531 BE153524 BE153576 BE153583
451385 85022.1 AA019761 AA017656 AA017374
439781 25924931 AA845538 AA890229
451331 287141 AK002039 AL117524 AV714494 AW954901 AL045243 BF955185 AU137860 AW880615 AW880496 AA256290 BE767078 N44348 AI886676
AA455877 N66571 AA999864 AU157344 AI817146 R54821 BE223107 AA455880 AI355752 BF589210 N63487 AI924033 AI923020 AI306145
AI919421 A1584169 AI250173 AI440227 AA669696 AW244040 AI358104 AI570333 AI418315 N94787 R72348 N94780 BF944396 BF754698
AW005707 N98831 BF001047 BF588691 AA318076 AW601474 AW883910 H10056 N63481 BE838574 BF909132 BI084973 BG257295 BG818471
BE348449 AI420623 AW271213 BE048764 W44682 AI887849 AW903942 AA975919 AA312915 BF948057 R55120 H10110 BI045196 AW880645
437158 59575.1 AL050068 AA160485 AW173544 AW296506 AW43986Q AI521563 AI702529 AI393606 AW138323 AA570109 H19504 BM021968 BF063327
BF593552 AA630766 AI597717 AI807128 AA523012 AI356250 AW451857 AA974203 AI762577 BF512552 AW007307 BE675286 AW450602
AA962057 AW516069 AI582546 BF221924 BF222543 AI801808 AW468599 AW000736 AI866625 AW235356 BM021837 AA911956 AI680606
W86516 T03370AW611634 H41653 AI468349 H19588AW090198 AW043993 R39847
406685 0.0 M18728 430385 MH497J NM.032013 AB044943 AF308609 BI769254 A1819262 AA845639 AI289Q73 BE670187 AA207127 T33Q98 AA633492 BE328324 AI083620 AI204945
AA903471 AI372602 AI049836 AI049737 BF000101 AI686167 BF436896 AI659189 T32971 AA311302 AW733149 AI435981 T03438 AA879206
AI972177 T33083 AA613910 AI971019 AI027140 AA853739 AI620528 A1637519 AI972307 BF054861 AK027665 BF082751 AI598127 T33663
AA204743 BE086660 F12132 T26372 BF765338 AA323106 AA322907 BI037062 BE315235 AV722868 BE254381 T66212 BE566142 T09034
AA406202 BF843940 A1743855 AA113356 BG990683 BE086729 BE535539
443144 16112.3 AB058726 A1651414 BE245990 BE245765 BF439734 AA648422 AA040639 AI340155 AA255928 AA278365 BE766296 AA280771 AL555562
AI474638 AI863068 BI260946 AK027039 BG615852 AI698039 AA252016 AA258886 BE905205 AW501167 BF514117 BI857400 AW297001
AI624923 AA125900 AW272165 AA190967 AA280729 AA035532 AW129692 AA125899 BG528645 BE614599 BE464693 A1560128 AA551511
AI351149 AL555561
432810 101919.1 BG292389 C06094AI668930AW104534AA310513 AA830127 AW134897M046953AW965490 AI810530 BF092924 AA334151 AA334725
D31302 R20723 AA263003 BI824635 AI276287 AI684428 AI524234 AI335035 AW014704 AI911443 AA972102 A1367512 AI126670 AW016017
AI286003 AI147163 AA626033 A1539156 AA565542 AI094253 AW512612 BE889628 AA744752 BE646306 AW471324 AA999975 AA863400
H17550 AI991439 R46187 BE929954 AA333976 D63102 BF744491
438874 52147.1 AF075017 R66779 R22463 H02780 400221 9287 3 NM.002082 L16862 BG828886 BE795217 BE904064 BE294526 BE297283 BE394617 BE935127 BE935106 F12351 BG823182 H16710 437751 643238.1 AW978796 AA767373 AW173343 AA836163 N27563 AA905328 R97032 410899 1063474.1 BF374577 AW809840 AW809996 AW809798 AW809695 AW809646 AW809738 BF374582 AW809716 AW809826 AW809802 AW809747
AW810152 453331 16559 1 BG571303 AA410586 AA035018 BG572117 BG620022 AA147247 BG005785 BG014448 R31981 H02668 H12498 R36203 BF992089 R73999
T49904 R75732 BI057974 T53681 AA147933 N50695 R68588 R25671 R31935 R25110 R36105 AK055628 BE157467 AW663674 AA190993 H01642 BF510304 AA626915 AA746952 AI161014 AA099554 BG572534 A1803329 AI809932 AI808765 AA411449 AI378760 AA976929 AI378620 AA909684 R75632 AI360919 AI350463 AW069127 AA411621 AA742532 H12451 BE208298 H03612 H12839 N58781 R75957 BF996484 AI240665 BF989591 BI056086 BG001590 BF107035 446526 11131.17 AK023419 BE464935 BE221668 AI148885 BI859909 AI374780 AA766892 AI347967 AI582917 AA477117 AA229236 AA652637 AA636108
AU134580 F21288 BF802607 BE769124 AV658891 H89616 AV659853 455577 1475566.1 BE006307 BE006341 BE006311
430858 73704.1 AF007190 AW820705 BE168488 AF007192 BF753303 BG978971 BG978568
400161 2656 2 U44839 NM.004651 BC000350 BI458316 AU117940 BG759024 BG749694 BE799505 BG831537 AI816335 AA325352 AL547005 AW157038
AI859331 AI816186 AU150786 AL043549 AW162880 AU159233 AI143169T03478 BE727648 AA764725 BE206603 AI369814 AI984369 AW157545 BE221486 H99016 AU159025 AI074496 AI494516 BE245950 AA704385 AA280862 AI479595 AI369776 BE671398 T05538 AA682249 BI677303 BE645335 AI359434 H92868 D52599 D53609 D54715 T06015 BE222174 AI954706 D53218 D53787 R69889 W86896 AI497670 R70771 BF309414 BE620147 BG910597 AW964968 BE836120 AL579715 H56512 D55956 BI044097 AL555239 BF220278 AA081991 AI819544 AW001573 AW131600 AI858764 D52367 W22034 BG818979 BG024561 BE702779 BI458863 BI910399 BG707755 BF348284 H10055 BI086315 BE620574 H41088 BG119517 W23267 W21941 AA328817
409959 2781.3 AW513804 BE179199 BE179195 BE179198 BE179204 BE162686 421341 1407.1 NM 007329 AF159456 AJ243212 AJ297935 AA295769 NM.017579 AJ243224 AI492875 AI796676 AI749838 AA918144 AI814590 AI923531 BF513992 AI720725 AH 50879 AI279072 AW612904 AI492104 AI284510 AI141231 AA613554 AW662148 AW769047 AA565985 AW612888 AU100513 BG955586 BG955588 AA295763 BE829414 BF760645 BG954398 AA295332 AA295795 BE932867 AW769569 T89953 BE934311
434051 73505.1 AF116622 AI114507 AA640834 BF111602 AA377999 410933 10646241 C16024 C15974 AW811066 AW811052 AW811020 406731 0.0 AI559131 446868 15525.1 AK074473 BC017997 BI831060 BF971101 AI886394 AI082824 AV708785 W86073 W07772 AV660737 AI816793 R52250 BG183529 AA633473 AI191256 R44763 R19947 BF571346 W86257
400231 MH494.5 BC013310 AF261085 BC004109 AY007133 BC009081 BC001601 NM.002046 M33197 BC020308 J02642 M36164 BE794233 AV721080 BE255459 BG926429 BG389312 BG477333 AI031799 BI763443 BI260432 AA989106 AV728576 BI091380 AA402499 AI200513 AI284734 AI223995 AI289749 BG283291 BM013814 AW438544 BM450203 F35435 F33262 BE890952 AA401181 BG939668 F35525 BI088182 F34674 F33506 BM471326 F34677 AW276712 AA187508 F34866 AA114245 AA522581 N23935 AI076923 AI018505 BE879774 BM465637 AI753078 BG222159 AA595947 BF970917 BI094125 AA719841 BE893087 BG775178 BE793983 BE797071 BF339134 BE409272 BE266456 BE796770 BE745957 BG755835 BE266758 BE259342 BM450181 BG748174 BE299322 BM423587 BM467637 BM452667 BM479516 BM452420 BE273297 BM466364 BM450640 BM478743 BM459094 BM455306 BM472001 BM478247 BM478771 BM480379 BM459071 BM450106 BM467584 BM464548 BM465044 BM450176 BF569359 BM462924 BM455329 BM471815 BI862301 BG331736 H04903 AA374894 BE902964 432745 112643.1 AA658826 AI821926 AI791191 AA635129 AA564492
412477 8669 2 AI220117 AI857837AI218371 BM091400 AI304964 AH98508 AI400738AW571549 AW950042 AI089943AA437280 AU150878 BF197070 AI267984
BF594181 BF196688 AI433152 AI338921 AI620364 AI280197 AA652531 AI674938 A1342447 AI620350 A1281295 AI148621 N54787 A1338121 AI281153 N51899 AI087072 AA954788 AW069054 AI346309 BG529629 AI340135 BF083036 AI167365 AW819657 AA935468 AI467868 AW148701 AI383720 BE047685 AW015498 AA937149 AA708346 AW771478 AW802508 H53334 AW389204 AW798230 AI553922 AI560688 AW950043 A1961682 AV706506 R01853 AA126514 N62757 A1536893 AI926052 AI418720 N99964 AI568933 AI915737 AI080691 AI185358 N48996 N68575 H82824 H60037 AI247247 T95664 BF593863 AI749637 AW088541 AA991294 AA887452 AI073726 AA633132 AA629674 AA629649 AA629656 AA578595 AI168758 AA804572 AI085786 AA994396 AA991209 AA948663 AA929054 AA927952 T87001 AA928210 AA629296 AW802267 AW384129 BF744400AA194110AI382839AA194837AA406284AI250750 R37035 AI525586 W01244 456076 8455.1 BG210376 BG217800 BE925778 W39114 BG682395 N70644 BE709097 AW275615 BC001469 AL564888 AI088126 AW003852 BF792438
AA161295 AW970131 AH27310AW029307AW192534AA843144AW606235 BE221641 AW008111 AA224203AA604507AW794761 AA134005 AA126850 N99165 AW769391 AW818302 AI269871 BE503027 AW401627 AA486231 AA486417 AA191542 AA028128 AA159991 AI498090 AI241024 BM145449 AA774661 AI626021 C18251 BE185811 AA291517 N38896 N59222 A1245611 AA169207 AI298572 AA169585 AI131139 AA157960 AI439983 AI208276 AA936061 W67305 AW337587 AI357055 W04739 AI214517 AA617789 AW241277 AI880213 AI582789 AI143996 BE814848 N49964 AI936222 AI817819 F09976 AA039349 AW805002 T35117 N94388 AI689530 AW384573 AW384555 AW384539 AW384473 AA129709 AW384466 BG194342 BG204579 BG027536 AL578075 AA399553 AW794949 T88866 AW511211 R26588 R36111 BG170598 BE937009 BG678833 AA862899 H96612 H02273 AA768487 BF211173 N32570 AA088287 R68451 AA297563 H16847 R80665 AA421891 W68402 R28379 R64119 R70109 R77661 R67963 BG701844 H68670 AA169664 AA114111 BE715243 R69317 BE715252 BE713804BG336586 NM.001679 BC011835 U51478 BM463117 AU119746 BI462090 B1227086 BG706303 BF059073 BG706532 BI544716 AI568735 BE858747 AU122881 AU126210 AI186547 AU134705 BE281323 AI147220 BE263820 AW973937 BG281863 BE858367 BE278941 AI262814 AI001194 AI391616 AI200862 N32564 AI161064 AI089818 BF514359 AI370916 AI341797 BE263168 AI218416 AI131098 AI2S5310 AI928440 AI066642 AI375442 AW028327 AI217792 AI161020 AI342854 AI221544 AI304700 AI343005 BM148839 AA831536 AW074258 BF940569 AI149876 AI914574 AA298442 AI241343AA668985AW272172AI160537 BG209220AA028152AA025989
430202 1233214.1 AW968345 AA468998T85775 424017 888651.1 AW966107 AA334317 AA333789 437272 176.2 AB075828 BG107783 AW021313 BI492345 AW385707 AW580860 AW296117 BE072066 AW580775 BF679498 AW580828 BE003666 BE003672 AW580851 AW580908 BI037146 AW580894 AW580864 H17858 N50343 N54223 F05579 F07386 F05578 AA773248 AA354359 AA330257 C20685 BE548300 AW968728 AW968554 AA777644 AA706896 AA682517 AA832267 BG165087 N51097 N51567 R95837 BI256603 W89042 R95836 R97364 AW975957 AA747943 AA811289
453542 885.22 BF568186 BF899745 AW836724 BE243668 437585 596988.1 AW976857 AI809001 AA769369 AW102732 AA761235 430763 1400 7 AL578301 AI337389 AI671302 AA978185 BF591738 AI765912 409031 9531.1 BF036043 AW190446 BG194731 AW662036 AI445021 BE937550 AW818972 AW393132 AA834685 BF112058 AV721682 H16423 AI270167 AI857345 AA937302 AW818444 BE929780 BG498678 BF155010 BI598271 BI599811 BE161728 AW578737 AW753711 AW379707 AW381918 BG506608AW028637AW994240 BF887392 BF790073AW381624AV727105 BF439618AA443174AI018009 N42850AW573242AI417258 AA463483 AI676131 AI167170 AA836627 AA443828 AW592922 AA235129 AA730278 AW439062 AW474332 BI043239 AW474342 BG708553 AW362423 BF090028 BE827256 R16550 R39478 R39479 R94368 BG540916 BM314745 AA251087 D54231 D55274 BF085805 D31589 AW966405 AW994425 D81879 BE093545 AW901107 AA383529 BI021552 R56420 N39976 AA573281 H82595 AA234955 BE093539 AW367006 BF358697 BF366318 AA663856 BE702099 BF035969 AI267384 A1267232 BE348320 AA621574 AA861212 BF083343 BF083341 AV745131 D53074 AW954476 AW954472 AA376836 AV724531 D53063 C14928 AA093287 AA062638 BG483558 BE940050 AA765954 T70171 BE938775 BE940057 D53502 AW373300 AL118798 BM128728 AA193411 AW444709 AW952455 AI887612 BF431948 BI496876 AI264159 BM128481 AI624657 AI689301 AI969467 AA861685 AA251595 AA625761 AA872090 AI826790 AA328366 BE827416 R75951 D56918 R68122 BE827384 AL118797 A1184164 AA164411 BI495332 BE858113 AI863860 H00660 T69849 AW780389 C14667 BE934995 BI018652 R92801 AA164410 H00752 AW373305 AW373299 AW373302 430108 1233254.1 AA928810 AW968393 AA465294AA811301
410276 641443 1 AA083514 AI554545 AW169852 A1363822 A1633826 A1656026 AI765624 AA147545 AA147552
400247 2764 1 BC022339 BC009610 BC010537 X79805 NM.006713 U12979 BM467814 BM450743 AU132951 AU137129 BG493425 AV758819 BG708412
BG705885 BG702217 AV716638 BG777009 BI545689 BI552153 BM476712 BG770858 BG527656 BG528277 BG391388 AV716861 BI602926 BG290073 BI667399 BM451469 BI667173 BI602139 BG532171 BI669216 BI544727 BG721852 AV716503 AV701327 BM090738 BI492000
AI308856 BI544904 AL599813 AV715829 AV716505 AV714587 AV717902 BF668072 AV716385 BI461927 BM090954 AV717826 BG503676
AV647719 BG501392 BG428433 BE895629 BM313117 AW021050 BG435032 BM152910 AA313503 AA872377 BG574714 AV712054 AV7326S6
AA252476 AV712759 AL599643 BE790872 BG654930 W73337 AW675377 AV760376 AV725139 AV716379 AA887165 BE830003 AW023796
AL599291 AI902948 BG944042 F00781 AA352483 BG217897 N33888 AW581924 BG654730 D31410 AA353088 D31288 AA295029 H95170
BE935104 AU139980 BG772963 BG776470 BG532512 BG105449 BI545421 AV715456 AW386083 BG699714 AL535832 AL514940 BG190861
BG210593 AW999254 H95138 AA353863 BE764809 N50375 BE091363 BG701255 BI860846 BI832485 BG168150 BG028647 BE546301
BG900321 BI909737 BG702363 BG614141 BG611137 BG700121 BF031492 N85802 AV715940 N51590 BG993478 BE172016 AW893622
439403 4937 10 AK056692 AF086220 AI375066 AA284293 W32566 AW797961 AA960897 AA504145 450724 4016Ϊ.1 BF060834 BI019048 AW862002 AK056737 AA429538 AW063311 AW440655 AW231970 AA428584 AA995028 AW854593 AA984131 AA552874
AA564758 AA528743 BG927275 BE045117 AW975234 AA664937 BF749390 BG928948 AA984546 BE009153 AV732487 BE078167 AW872716
AW063245 AA578441 AI820704 AI732283 R55428 BF999154 BF880485
432077 452948 1 AL134685 AW972760 AA525319 AA526644 AA525342 AA526632 AA525296 AV739423 AW972755 449625 249224.1 BI918168 AW779760 N48674 AI375997 AA235370 BG699146 AI913631 AI498402 AI016320 AA323193 R49021 D59344 BG986750 N45526
BG986917 T61382 R49391 R45432 AI203107 R35004 F07491 R25094 R35360
455047 1092329 1 AW852530 AW852526 AW852527 AL597969 410934 1064652.1 AW811114 AW811095 AW811094AW811124AW811157 AW811054 AW811087 454600 1063489.1 AW810001 BF374633 AW809694AW809672 BF374748 BF374562 AW810209AW810092AW809786AW810428 AW810429AW809884 BF374650
BF374641 BF374764BF374744AW810552 BF374678 BF374653 BF374579AW810168AW810170 BF374611 BF374676 BF374667AW810353
BF374682 AW810154 BF374688 BF374565 BF374757 BF374637 BF374743 BF374719 AW809664 BF374643 BF374680 BF374714 BF374708
BF374716 AW810432 BF374691 BF358066 AW810006 AW810345 AW809960
455500 1228737.1 AW963582 BE064192 BE064169 BE152580 AW963587 411745 43036 8 AV704306 BF368780 AW867826 AW859896 418869 12789 14 AA229762 AA230035 432093 1237011 1 AW972670 AA525808 H28359 H28383 452239 10116.4 BG034853 AW173315 AW303375 BG190225 BG939153 BF057308 AA600736 AI751258 AI090486 BE939504 AW631492 AI768270 AI862133
AA417652 BE378218 AA599207 AW794702 AA024968 AA446024 AI148235 AI191710 BI493797 AI272646 BI493796 AA634323 AI754332
AA258414 C05155 AI218226 AI039656 AI350380 AI084698 AI754989 AI673545 AI432010 AI751035 AA375571 AA446297 BG216743
406851 0 0 AA609784 R97304 430353 10288.1 BC010106 AL560552 AU133296 AU133086 BE268567 BE268523 BI544879 BE398161 BG473088 BI544445 BE258021 BE296339 BE255040
BE263020 BG706790 AL598627 AW952337 BG758113 AW512753 BE267666 BE253415 BI225718 BE268350 BE258245 BI224965 AW772605
BG723903 BE397282 BI196341 BG702880 A1878949 AL600437 AA416759 BE259917 AI031582 BF512142 AI088248 BE560328 AI802623
AI288613 AL597585 AW768553 AI816352 BF732831 BI225687 AA833686 AA722593 AA807750 AW068064 AA405187 AI923236 N51593 AL527710
BG282576 AL525927 AL525971 BI869547 AI064725 R91856 H46814 H20112 W01682 AW848870 AW848585 AW376662 AW848985 AW848937
AW848862 AW848581 AW848512 AW848176 AW752623 AW752618 AW376822 AW376821 AW376684 AW376623 AW376622 BE706047
AW752602 AW752691 AW752674 AW752652 AA379167 AW752610 AW752684 AW752613 AW752660 AW848709 AW848576 AW849155
AW848981 AW848980 AW848979 AW848978 AW848973 AW848916 AW848713 AW848708 AW848642 AW848641 AW848639 AW848573
AW848493 AW848492 AW848489 AW848488 AW848487 AW848353 AW848352 AW848220 AW752698 AW752697 AW752682 AW752681
AW752680 AW752679 AW752664 AW752651 AW752638 AW752637 AW752636 AW752628 AW752626 AW752624 AW752619 AW752596
AW752608 AL582019 BE875587 AL529175 AW965868 BG686208 AA259073 BE696973 AA459543 AA358314 W40564 BF926427 AW849000
AW848718 AW848515 AW848507 AW848444 AW848440 AW848232 AW848222 AW752657 AW376786 AW376781 AW376615 AW376614
BI752581 AA534520 AI748906 AA047799 AI014753 AL514460 AL581982 BG743146 W24171 H20102 H11227 AW752607 AW006596 AW130378
BE716519 AW752661 AW848289 BF349557 AW752612AW752632AW848910 NM.004077 AF047042 AL560606 BI765896 BI196831 BI855656
BE906674 BG749937 BE535486 BE019810 AA313713 AA992542 AA332541 AA682985 AA356125 BE140478 BG750945 BI457548 BG025661
BF326302 AA325019 BG980676 AA337465 AA321974 BG949285 BG427585 R23979 BG611485 BE560678 W16977 N50379 BG824101 BG471750
BI463171 W04691 AU099360 BG471590 BM011999 BE262945 BE559801 BF756438 BE881957 BE314546 BG911831 BG150811 BG112017
AA157518T92368AW752620
431323 1235269 1 AW970623 AA502839 AA502819 442195 15007.1 U81984 NM_001430 BE907085 BI333232 AI021986 AU138476 C18601 U51626 AU100517 BI054387 AU076970 BE786454 BG010080 AW377189
BF998789 AA368139 R11396 T83613 BG006324 BI012404 BG001643 BF757957 AL549361 AL544018 BE002870 BE929314 BE090199 AL046650
BI053717 BE929315 BI054967 BF960055 BF925432 R05421 BF922073 T70331 BI004403
TABLE 34C:
Pkey: Unique number corresponding to an Eos probeset Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham, et al." refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al. (1999) Nature 402:489-495.
Strand: Indicates DNA strand from which exons were predicted. NLposition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLposition
405443 7408143 Plus 90716-90887,101420-101577
401645 7657839 Minus 34986-35133
401673 7689903 Minus 122587-122705,122765-123047
405120 8099940 Plus 140176-140340
401785 7249190 Minus 165776-165996,166189-166314,166408-16656
402333 8844110 Minus 165693-165856
404942 7382153 Plus 92095-92252
403362 8571772 Plus 64099-64260
402641 9958129 Minus 122596-125136
405600 5923640 Plus 26662-27225
405061 7656744 Minus 132492-132932
402327 7656695 Minus 108675-108770,109801-109910
404342 9838093 Plus 115854-116033
404429 7407979 Plus 31352-31498
403344 8569726 Plus 70823-70990
401593 7230957 Plus 10368-10572,11293-12356
406461 9756020 Minuε 158842-159136
400609 9887671 Minus 92037-92247
402674 8077108 Minus 39290-39502
401677 9965537 Minus 62856-63086,63603-63884
405579 6456174 Plus 100996-101542
405797 1934909 Minus 5599-5681,5821-6104 405159 9966252 Pluε 79659-79804
403520 7684483 Minuε 97621-98084
402538 9801137 Minus 96314-96539
404151 7534014 Minus 69038 69399
400496 9743564 Plus 41515-41695
403010 3132346 Plus 78385-79052
406387 9256180 Plus 116229-116371,117512-117651
402885 9926751 Plus 71919-72049
404501 7229859 Minus 37270-37526
402487 9797538 Plus 75677-75843
404455 7677926 Minus 26927-27611
401067 5764724 Minus 153366-153509
402324 7630361 Plus 26052-26803
402013 7407997 Plus 174540-174634,175449 175568
401116 9966559 Plus 123579-124447
402998 2996643 Minus 17175-17373
405550 1552494 Plus 91720-92115
402917 7406502 Minus 1034-1177,3143-3266
402504 9797871 Plus 12366-12614
405491 5801645 Plus 81857-82045
400818 8569994 Plus 172644-172765,173085 173200
406475 9797684 Plus 125417-125563,128052-128180
401025 8117518 Minus 179287-179483,181044-181166,181844-18203
402308 7340295 Minus 92080-93638
405213 6692345 Minus 50267-51151
400740 7329267 Minus 79920-80510,80576-80746
402825 6165330 Minus 78572-78807
405973 8247789 Plus 103859-104254
405818 4071056 Plus 29055-29196
402621 9930950 Plus 130806-131036
401311 9212516 Minus 180124-180754
401899 7230209 Minus 155620-155815
403579 8101179 Minus 36167-36365
404600 8705107 Plus 118354-118444,118649-118792
405531 9665194 Plus 35602-35803
405542 9857564 Plus 71331-72183
405131 8516051 Minus 136764-137594
403026 7670575 Plus 56521-56840
405369 2078469 Minus 34183-34357,35686-35751
405932 7767812 Minus 123525-123713
405156 9966228 Plus 146733-146860,147899-147961,153127-15325
402174 8575912 Plus 253499-253674
405536 9795661 Plus 164091-164162,164397-164516,166720-16679
406109 9127147 Minus 58328-58485
403162 9838085 Plus 82652-83613
401404 7710968 Plus 136474-136646
403167 9838127 Plus 162599-162935
402209 8576119 Minus 53315-53472
400986 8085497 Minus 63140-63319
404975 3419864 Minus 86096-86605
404926 7341919 Minus 150411-151484
TABLE 35A About 323 genes upregulated in hypersensitivity pneumonitis relative to idiopathic pulmonary fibrosiε or non-spxific interstitial pneumonitis
Pkey Unique Eos probeset identifier number
ExAxn Exemplar Accession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of HP Alε divided by 90th percentile of IPF Als, where 15th percentile of normal tisεue Alε waε εubtrxted from both the numerator and denominator
The minimum value for the numerator and denominator waε εet to 50
R2 90th percentile of HP Alε divided by the median of IPF Alε, where the minimum value for the numerator and denominator was set to 50
Pkey ExAccn UnigenelD Unigene Title R1 R2
402550 Target Exon 403 470
421563 NM 006433 Hs 105806 granulysin 3 37 270
424326 NM.014479 Hs 145296 ADAM-like disintegnn protease, dxysin 331 242
417967 BE244373 Hs 1119 nuclear rxeptor subfamily 4, group A, m 309 1 51
411089 AA456454 cell division cycle 2-lιke 1 (PITSLRE pr 299 1 28
416350 AF188625 Hs 189507 phospholipase A2, group HD 271 1 43
406654 M90686 Hs 73885 HLA-G histxompatibility antigen, class 270 1 53
459705 BE082764 Hs 270252 ESTs, Weakly similarto androgen rxepto 270 1 14
412610 X90908 Hs 74126 fatty xid binding protein 6, ileal (gas 269 299
452194 AI694413 olfactory rxeptor, family 2, subfamily 263 267
447709 U97145 Hs 19317 GDNF family receptor alpha 2 263 1 52
410910 AW810204 gb MR4-ST0125 021199-017-d08 ST0125 Homo 259 1 00
454671 AW812929 Hs 336908 ESTs 250 234
441859 AW194364 Hs 94814 interleukin 4 induced gene-1 protein (FI 245 1 90
422398 AI476149 Hs 334489 hypothetical protein FLJ21992 245 1 36
403244 C2002870* gι|82698|pιr||JQ0985 hydroxypr 240 1 53 415462 R52692 Hs 12698 ESTs 240 1 00
447028 AI973128 Hs 167257 brain link proteιn-1 233 1 64
412394 AW984150 gb PM2-HN0008-170300 001-h09 HN0008 Homo 232 1 00
450165 AA007235 Hs 63931 ESTε 2 32 1 32
431093 AB031038 Hs 301704 eomesodermin (Xenopus laevis) homolog 230 1 81
444090 S69115 Hs 10306 natural killer cell group 7 sequence 228 1 69
413682 BE156991 gb RC3-HT0371-290100-013-e02 HT0371 Homo 227 1 59
441320 AI768724 fibulin 1 227 1 87
456766 R87310 Hs 7740 oxysterol binding protein like 1 227 1 36
420340 NM 000734 Hs 97087 CD3Z antigen, zeta polypeptide (TιT3 com 226 1 98
459721 AI299050 Hs 143835 gb qn14d12 x1 NCI_CGAP_Lu5 Homo εapienε 225 1 82
405452 Target Exon 225 1 29
458079 AI796870 Hs 54277 DNA εegment on chromoεome X (unique) 992 225 5 80
401447 Target Exon 225 1 55
423066 Y18264 Hs 123094 εal (Drosophila) like 1 224 1 51
441704 AI458766 Hs 192125 ESTs 224 1 00
405097 ENSP00000175238* A disintegnn and metal 224 1 00
408544 AW293825 ESTs 222 1 95
413454 BE141162 gb MR0-HT0076 021299 001-d03 HT0076 Homo 220 226
444404 M31525 major histxompatibility complex, class 2 20 1 37
418460 M26315 Hs 85258 CD8 antigen, alpha polypeptide (p32) 219 288
436063 AK000028 ribosomal protein S24 219 1 42
429212 NM_001504 Hs 198252 G protein-coupled receptor 9 2 18 1 22
400712 Target Exon 218 1 00
417929 R27219 Hs 74647 Human T-cell receptor active alpha chain 2 17 1 79
403478 NM_022342 Homo sapienε kinesm protein 9 2 17 1 80
418747 AJ249977 Hs 88049 protein kinase, AMP-activated, gamma 3 n 217 1 76
429712 AW245825 Hs 211914 ENSP00000233627* NADH-ubiquinone oxidore 216 1 44
451668 Z43948 Hs 326444 cartilage acidic protein 1 2 16 212
414020 NM 002984 Hs 75703 small inducible cytokine A4 (homologous 215 288
456057 AA947457 Hs 135560 ESTs, Weakly similar to T43458 hypotheti 215 250
444346 AI142274 ESTs 2 15 238
418918 X07871 Hs 89476 CD2 antigen (p50), sheep red blood cell 214 1 93
451318 AA029888 Hs 95071 ESTs 214 1 16
458935 Y16521 Hs 24812 CDP-diacylglycerol synthase (phosphatida 2 13 1 52
417105 X60992 Hs 81226 CD6 antigen 213 261
408219 BE061111 Hs 254211 gb QVO-BT0041-011199 039402 BT0041 Homo 2 13 1 94
420137 AA306478 Hs 95327 CD3D antigen, delta polypeptide (TιT3 co 211 266
443711 N67861 Hs 49390 ESTs 210 1 00
423234 AA323534 Hs 296162 AD037 protein 210 1 52
416975 NM 004131 Hs 1051 granzyme B (granzyme 2, cytotoxic T-lymp 209 374
425280 U31519 Hs 1872 phosphoenolpyruvate carboxykinase 1 (εol 208 1 84
405827 Target Exon 208 1 00
406909 L20777 Hs 73885 gb Human MHC class I HLA-G gene (HLA-A33 208 229
437295 AW779318 Hs 88417 ESTs 207 1 72
424281 AA766243 gb oa13b11 s1 NCI.CGAP.GCB1 Homo sapiens 207 1 00
430413 AW842182 Hs 241392 small inducible cytokine A5 (RANTES) 207 216
423901 AA333006 gb EST37064 Embryo, 8 week I Homo sapien 207 1 50
405075 Target Exon 207 1 15
457423 AK000642 Hs 265018 hypothetical protein FLJ20635 207 267
406267 Target Exon 207 1 30
423365 AA324992 Hs 257168 ESTs 206 1 70
449970 AI678058 Hs 201227 ESTs 206 248
430733 AW975920 Hs 121036 ESTs 206 1 00
446323 AI288274 Hs 345792 ESTs 206 1 00
402240 Target Exon 205 1 94
451404 AA460775 Hs 6295 ESTs, Weakly similar to T17248 hypotheti 205 1 44
424463 AW195353 Hs 119903 ESTs 204 1 32
400107 Eos Control 204 242
404811 NM.021096 Homo sapienε calcium channel, 203 218
403589 Target Exon 203 1 57
404088 Target Exon 203 1 00
414991 C17898 gb C17898 Human plxenta cDNA (TFujiwara 203 204
429073 AA446167 Hs 47385 ESTε 203 310
426274 D38122 Hs 2007 tumor necrosis fxtor (ligand) superfami 202 1 92
401897 C17001987 gι|7303380|gb|AAF58438 1| (AE0 202 1 55
431094 AW972276 Hs 116195 ESTs 202 1 00
424899 AL119387 Hs 119062 ESTs 201 241
419711 C02621 Hs 159282 ESTs 201 1 92
459019 AA017156 Hs 40719 hypothetical protein KIAA1164 201 1 76
405453 NM.005748* Homo εapienε YY1-aεsocιated f 201 1 24
402516 Target Exon 201 1 00
457365 AA577297 Hs 303249 EST 201 236
407928 NM 002262 Hs 41682 killer cell Ixtin like rxeptor subfami 201 262
436553 AW407157 Hs 8997 immunoglobulin lambda Ixus 200 1 64
406266 Target Exon 200 246
419409 AW297831 Hs 143792 hypothetical protein MGC2656 200 1 60
435028 AW193035 Hs 187370 ESTs 200 1 55
404696 NM_013443 Homo sapiens CMP-NeuAC (beta)- 200 1 21
403533 Target Exon 200 1 17
411673 BE064863 gb RC1-BT0313-110300 015406 BT0313 Homo 200 1 00
424148 BE242274 Hs 1741 integnn, beta 7 1 99 366
419833 AA251131 Hs 220697 ESTs 1 99 1 69 423196 AK001866 Hs 125139 hypothetical protein FLJ 11004 199 184
426416 AW612744 Hs 169824 killer cell lectiπ like receptor subfami 198 256
449317 AW293413 Hs 132906 19A24 protein 198 244
424321 W74048 Hs1765 lymphocyte specific protein tyrosine kin 197 251
422109 S73265 Hs1473 gastπn releasing peptide 197 332
424218 AF031824 Hs 143212 cystatin F (leukocystatm) 196 186
406303 C16000922 gι|7499103|pιr||T20903 hypothe 196 216
438676 AA813745 Hs 123446 ESTs 195 362
404240 NM.018950 Homo sapiens major histocompat 195 206
404056 Target Exon 194 260
425508 AA991551 Hs 97013 Homo sapiens Similar to RIKEN cDNA 2310 193 324
429819 AL133011 Hs 225108 Homo sapiens mRNA cDNA DKFZp434P201 (fr 193 235
416941 BE000150 Hs 48778 niban protein 192 224
446998 N99013 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 192 544
409153 W03754 Hs 50813 hypothetical protein FLJ20022 192 608
419490 NM 006144 Hs 90708 granzyme A (granzyme 1, cytotoxic T-lymp 190 552
446608 N75217 Hs 257846 ESTs 190 463
425367 BE271188 Hs 155975 protein tyrosine phosphatase, rxeptor t 189 150
414812 X72755 Hs 77367 monokine induced by gamma interferon 189 493
422994 AW891802 Hs 296276 ESTs 188 330
424517 AI539443 Hs 137447 Homo sapiens cDNA FLJ12169 fis, clone MA 188 217
433671 AW138797 Hs 132906 19A24 protein 188 183
412116 AW402166 Hs784 Epstein Barr virus induced gene 2 (lymph 186 312
447656 NM 003726 Hs 19126 src kinase assxiated phosphoprotein of 186 188
432468 AW402155 Hs 3003 CD3E antigen epsilon polypeptide (TιT3 184 165
419231 AL046294 Hs 136245 ESTs, Weakly similar to T17227 hypotheti 183 246
427527 AI809057 Hs 153261 immunoglobulin heavy constant mu 182 207
431574 AW572659 Hs 261373 hypothetical protein dJ4340143 182 263
436485 X59135 Hs 156110 immunoglobulin kappa constant 182 275
432606 NM 002104 Hs 3066 granzyme K (senne protease granzyme 3, 181 456
421379 Y15221 Hs 103982 small inducible cytokine εubfa ily B (Cy 180 510
448569 BE382657 Hs 21486 εignal tranεducer and activator of trans 179 189
429670 L01087 Hs 211593 protein k ase C, theta 178 334
412584 X54870 Hs 74085 DNA segment on chromosome 12 (unique) 24 178 355
413869 NM 000878 Hs 75596 interleukin 2 receptor, beta 178 197
406672 M26041 Hs 198253 major histocompalibility complex clasε 176 212
452203 X57522 transporter 1, ATP binding casεette, εub 175 155
426451 AI908165 Hs 169946 GATA binding protein 3 (T-cell rxeptor 173 204
447131 NM 004585 Hs 17466 retinoic acid rxeptor responder (tazaro 173 156
414512 AL044336 Hs 6831 golgi phosphoprotein 1 173 200
426752 X69490 Hs 172004 titin 173 262
444793 U89281 Hs 11958 oxidative 3 alpha hydroxysteroid dehydro 172 230
452334 D60471 Hs 13390 gb HUM111D09B Clontxh human fetal brain 172 212
446227 AI281459 Hs 270114 ESTs 172 248
407830 NM 001086 Hs587 arylxetamide deacetylase (eεterase) 172 272
423799 AW026300 Hs 132906 19A24 protein 171 240
458332 AI000341 ESTs 170 371
408380 AF123050 Hs 44532 diubiquit 170 271
437644 AA748575 Hs 136748 lect like NK cell receptor 170 258
402736 NM_024852 Homo sapiens hypothetical prot 169 210
438866 U44385 Hs 325495 tissue inhibitor of metalloprotemase 2 169 139
422846 BE513934 Hs 1583 neutrophil cytosolic fxtor 1 (47kD, chr 168 202
426202 BE266484 Hs 82916 chaperonin containing TCP1, εubumt 6A ( 168 214
414646 AA353776 Hs901 CD48 antigen (B-cell membrane protein) 168 330
420440 NM 002407 Hε 97644 ammaglobin 2 167 242
416967 BE616731 Hε 80645 interferon regulatory factor 1 167 149
415823 R81864 Hε 205103 ESTs 165 216
421924 BE514514 Hs 109606 coronin, xtin binding protein, 1A 165 158
427307 AF117947 Hs 174795 PDZ domain-containing guanine nucleotide 163 194
444929 AI685841 Hs 161354 ESTε 163 216
439237 AW408158 Hs 318893 ESTε, Weakly similar to A47582 B-cell gr 163 174
418196 AI745649 Hs 26549 KIAA1708 protein 162 276
428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy 162 442
438568 R98865 Hε 11135 major histxompatibility complex, class 162 174
430308 BE540865 Hs 238990 cyclm-dependent kinase inhibitor 1B (p2 162 185
433934 AW273261 Hs 216292 ESTs 162 200
443559 AI076765 Hs 269899 ESTs, Moderately similar to ALU8_HUMAN A 161 200
450000 AI952797 Hs 10888 hypothetical protein FU21709 161 146
415349 AI766697 Hs 13231 ESTε 160 200
406656 M16714 Hs 89643 major histxompatibility complex, class 160 147
456974 M12529 Hs 169401 apolipoprotein E 160 163
416401 N80139 Hs 268916 ESTs 159 168
439372 AF088033 Hs 159225 ESTs 159 204
434666 AF151103 Hs 112259 T cell receptor gamma Ixus 159 408
417696 BE241624 Hs 82401 CD69 antigen (p60 early T-cell activati 158 306
417427 M90391 Hs 82127 interleukin 16 (lymphxyte chemoattrxta 158 237
431903 AB029488 Hs 272100 SMS3 protein 157 214
413472 BE242870 Hs 75379 solute earner family 1 (glial high affi 157 228
425762 BE244076 Hs 159578 AT-hook transcription factor AKNA 156 146
412472 AW975398 Hs 293836 ESTs 156 226
451406 AI694320 Hs 6295 ESTε, Weakly similar to T17248 hypotheti 156 238
412568 AI878826 Hs 74034 caveol 1, caveolae protein, 22kD 155 167
449835 AW979300 Hs 293813 ESTs 155 216 405545 Target Exon 155 264
435299 AI745458 Hs 343026 ESTs, Weakly similar to T20593 hypotheti 155 381
422060 R20893 Hs 325823 ESTs, Moderately similar to ALU5_HUMAN A 154 214
424243 AI949359 Hs 143600 ESTs, Highly similar to cis Golgi locali 153 262
457500 NM 002759 Hs 274382 protein kinase, interferon Inducible dou 153 204
424541 AW392551 Hs 180559 ESTs, Weakly similar to A56194 thromboxa 153 200
439039 AI656707 Hs 48713 ESTs 153 238
449523 NM 000579 Hs 54443 chemokine (C-C motif) receptor 5 152 265
457718 F18572 Hs 22978 ESTs, Weakly similar to ALU4_HUMAN ALU S 152 206
415198 AW009480 Hs943 natural killer cell transcript 4 152 140
431594 AI823999 ESTs 152 212
432656 NM_000246 Hs 3076 MHC class II transactivator 152 220
422426 W79117 Hs 58559 ESTε 152 222
414372 AA143654 gb zo65a02 r1 Stratagene pancreaε (93720 151 280
427247 AW504221 Hs 174103 integnn, alpha L (antigen CD11A (p180), 150 167
433043 W57554 Hs 125019 lymphoid nuclear protein (LAF-4) mRNA 149 312
406621 X57809 Hs 8997 immunoglobulin lambda Ixus 149 178
419166 AA234638 Hs 293584 ESTs 149 210
418323 NM 002118 Hs 1162 major histxompatibility complex, claεε 149 147
435304 H10709 Hs 269524 ESTε 148 296
452834 AI638627 Hs 105685 KIAA1688 protein 148 214
446616 R65964 Hs 334873 ESTε, Weakly similar to ALU8 HUMAN ALU S 148 138
429272 W25140 Hs 110667 ESTs 148 319
428379 X06026 Hs2259 CD3G antigen, gamma polypeptide (TιT3 co 148 166
433231 AB040926 Hs 143552 KIAA1493 protein 147 216
408847 AW290997 Hs 30348 ESTs 146 208
405441 Target Exon 146 299
443378 AW392550 Hs 9280 proteasome (prosome, macropain) subunit, 145 156
459644 AW197203 gbxm38b01 x1 NCI_CGAP_GC6 Homo sapiens 145 244
431433 X65018 Hs 253495 surfactant pulmonary-associated protein 145 170
422934 BE244189 Hs 122492 hypothetical protein 144 127
409799 D11928 Hs 76845 phosphoseππe phosphatase-like 144 346
406698 X03068 Hs 73931 major histxompatibility complex, class 144 171
421407 T82331 Hs 182278 ESTs, Weakly similar to CGHU6C collagen 143 156
413420 AW410235 Hs 75348 proteasome (prosome, macropain) activato 143 125
400269 Eos Control 143 202
420973 AA743415 Hs 291368 ESTε 142 206
442104 L20971 Hs188 phoεphodieεterase 4B, cAMP-spxific (dun 142 220
430015 AW768399 ESTs 141 206
427648 AI376722 Hs 180062 proteasome (prosome, macropain) subunit, 141 131
418870 AF147204 Hs 89414 chemokine (C-X-C motif), receptor 4 (fus 140 172
437479 R61866 Hs 101277 ESTs 140 252
425345 AU077297 Hs 155894 protein tyrosine phosphatase, non recept 140 217
416030 H15261 Hs 21948 ESTs 140 262
419886 AA251562 Hs 146168 ESTs, Weakly similar to AF1180231 SH3 d 140 168
443951 F13272 femtm, light polypeptide 140 164
414875 H42679 Hs 77522 major histxompatibility complex, class 140 142
412471 M63193 Hs 73946 endothelial cell growth fxtor 1 (platel 140 134
428782 X12830 Hs 193400 interleukin 6 rxeptor 140 230
400680 NMJJ14207 Homo sapiens CD5 antigen (p56- 139 193
428289 M26301 Hs 2253 complement component 2 139 139
441410 AA932689 Hs 233304 ESTs, Weakly similar to I38022 hypotheti 139 142
406645 M57466 Hε814 major histxompatibility complex, class 139 145
441379 AW175787 Hs 334841 selenium binding protein 1 138 132
416636 N32536 Hs 42645 εolute earner family 16 (monxarboxylic 138 204
418707 U97502 Hs 87497 butyrophilin, subfamily 3, member A2 138 135
423526 AB011086 Hs 129739 KIAA0514 gene product 137 141
424168 L29277 Hs 321677 signal transducer and xtivator of trans 137 133
431723 AW058350 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 137 174
426437 BE076537 Hs 169895 ubiquitin-conjugatmg enzyme E2L 6 135 138
446566 H95741 Hs 17914 membrane-spanning 4-domams, subfamily A 135 154
452353 C18825 Hs 29191 epithelial membrane protein 2 134 147
448406 AW772298 Hs21103 Homo sapienε mRNA, cDNA DKFZp564B076 (fr 131 177
435106 AA100847 Hs 5978 ESTε, Highly similar to AF1746001 F-box 131 153
444633 AF111713 Hs 286218 junctional adhesion molxule 1 130 137
430998 AF128847 Hs 204038 indolethylamineN-methyltransferase 129 149
419092 J05581 Hs 89603 mucin 1, transmembrane 128 136
451864 N20370 Hs 69547 ESTs 128 142
421140 AA298741 Hs 102135 signal sequence rxeptor, delta (traπslo 128 131
412790 NM 014767 Hs 74583 KIAA0275 gene product 128 163
446272 BE268912 Hs 14601 hematopoietic cell-specific Lyn subεtrat 128 138
422530 AW972300 Hs 118110 bone marrow εtromal cell antigen 2 128 136
435822 T95594 Hs 187435 ESTs 127 182
455863 AA907305 Hs 36475 ESTs 127 136
404277 NM 019111* Homo sapiens major histxompa 127 152
413497 BE177661 gb RC1-HT0598-020300011-h02 HT0598 Homo 127 154
441835 AB036432 Hs184 advanced glycosylation end product-speci 127 153
418371 M13560 Hs 84298 CD74 antigen (invanant polypeptide of m 126 127
434747 AA837085 ESTε 126 160
425320 U29344 Hs 83190 fatty xid εynthaεe 125 135
452363 AI582743 Hs 94953 Homo εapienε, Similar to complement comp 125 141
434644 H98071 Hs 4055 chromosome 21 open reading frame 50 125 130
404854 Target Exon 125 157 406973 M34996 Hs 198253 major histocompalibility complex, class 125 157
421071 AI311238 Hs 104476 ESTs Weakly similar to CGHU1E collagen 124 126
431779 AW971178 Hs 268571 apolipopratem C-l 124 139
416047 BE439894 Hs 78991 DNA segment numerous copies, expreεsed 123 208
406826 AW516005 Hs 84298 CD74 antigen (invariant polypeptide of m 123 120
426836 N41720 Hs 172684 vesicle associated membrane protein 8 (e 122 124
415661 AF057307 Hs 78575 prosaposin (vaπant Gaucher disease and 122 116
406824 AW515961 Hs 84298 CD74 antigen (invaπant polypeptide of m 122 117
420679 X57152 Hs 99853 fibπllaπn 122 130
443071 AL080021 Hs 8986 complement component 1, q subcomponent 122 158
418090 U57059 Hs 83429 tumor necrosis factor (ligand) superfami 121 133
430250 NM 016929 Hs 283021 chloride intracellular channel 5 121 160
406825 AI982529 Hs 84298 CD74 antigen (invariant polypeptide of m 120 120
436906 H95990 Hs 181244 major histocompalibility complex class 119 127
422241 Y00062 Hs 170121 protein tyrosine phosphatase, rxeptor t 119 162
408279 AF216965 Hε 44095 Homo sapienε, clone MGC 12617, mRNA, com 118 125
411372 AI147861 Hε 213289 low density lipoprotein receptor (famili 117 133
444342 NM 014398 Hs 10887 similar to lysosome assxiated membrane 116 149
406906 Z25424 gb H sapienε protein seπne/thrxmne ki 116 115
451558 NM 001089 Hs 26630 ATP binding cassette sub-family A (ABC1 116 138
432805 X94630 Hs3107 CD97 antigen 116 122
427383 NM 005411 Hs 177582 surfactant pulmonary assxiated protein 116 141
438086 AA336519 Hs 83623 nuclear rxeptor subfamily 1, group I, m 116 136
443623 AA345519 Hs 9641 complement component 1, q subcomponent 115 127
429832 AW293301 Hs 288472 ESTs Weakly similar to UBPF.HUMAN UBIQU 115 172
438183 BE263252 Hε 6101 hypothetical protein MGC3178 115 121
432680 T47364 Hs 278613 interferon, atpha- ducible protein 27 114 121
406782 AA430373 gb zw20f11 s1 Soares ovary tumor NbHOT H 114 141
414662 AL036058 Hs 76807 major histxompatibility complex class 112 125
452547 AA335295 Hs 74120 adipose specific 2 111 139
414803 X03100 Hs914 Human mRNA for SB clasεll hiεtxompatibi 111 122
430280 AA361258 Hε 237868 interleukin 7 rxeptor 110 173
441384 AA447849 Hs 288660 retinoic xid induced 3 109 122
424614 X54486 Hs 151242 serine (or cysteine) proteinase inhibito 109 114
419200 AW966405 EST 108 164
416511 NM 006762 Hs 79356 Lysoεo al aεεxiated multispaπmng membr 108 118
409428 M33680 Hs 54457 CD81 antigen (target of antiproliferativ 107 112
447023 AA356764 Hs 17109 integral membrane protein 2A 107 171
421481 AW391972 Hs 104696 KIAA1324 protein 107 158
406868 AA505445 Hs 300697 immunoglobulin heavy constant gamma 3 (G 107 123
412819 T25829 Hs 24048 FK506 binding protein prxursor 106 145
418253 AA215539 Hs 283643 Homo εapienε cDNA FU11606 fis, clone HE 106 124
431243 U46455 Hs 252189 syπdecan 4 (amphiglycan ryudxan) 105 117
448133 AA723157 Hs 73769 folate rxeptor 1 (adult) 104 121
407112 AA070801 Hs 51615 ESTε, Weakly similar to ALU7.HUMAN ALU S 104 914
418156 W17056 Hs 83623 nuclear rxeptor subfamily 1, group I m 103 665
438089 W05391 nuclear rxeptor subfamily 1, group I, m 103 800
429615 AF258627 Hs 211562 ATP-binding cassette, sub-family A (ABC1 101 125
406722 H27498 Hs 293441 Homo εapienε SNC73 protein (SNC73) mRNA, 100 118
438091 AW373062 nuclear rxeptor subfamily 1, group I, m 099 1284
407018 U49869 N .018955 Homo sapiens ubiquitin B (UBB) 099 107
412896 AW804157 Hs 308026 major histxompatibility ∞mplex, class 098 157
435523 T62849 Hs 11090 membrane-spanning 4-domaιns, εubfamily A 097 140
426530 U24578 Hs 278625 complement component 4A 096 128
456898 NM 001928 Hs 155597 D component of complement (adipsin) 095 129
407241 M34516 gb Human omega light chain protein 141 094 111
425371 D49441 Hs 155981 mesothelin 092 145
431369 BE184455 Hs 251754 sxretory leukocyte protease inhibitor ( 091 128
TABLE 35B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT Number Accesεion 411089 5597_6 BI009308 B1009893 BF922023 BF922909 BF922913 BF922096 BF957733 BE701791 AA456454 AA579876 BF933710 AA091294 BI007291
AW905577 AW975593 AA713730 AW836781 AA666384 AA551106 BF594606 AI082382 AI955808 AI679895 AI679386 BF435555 AA586369
AA551351 AA595822 AA565188 BF808855 AA584921 N86077 AA601031 AA633188 AA514764 AA454562 AA551297 AA936109 BI009389
AW897806 BE815442 BF739374 BI009310 BF925422 BF933709 BF922034 BF925465 BI009680
452194 90339 A1694413 AW994700 AI912946 N73548 AI082035 AW271652 W24189 W24182 AI719718 AA024658 AW810120 AW015394T79755 AA988043
AI709339
410910 1063929 1 AW810196AW810555AW810507AW810204AW810619AW810534
412394 1174616 AW947794 AW947783 AWS47802 AW947798 AW947792 AW984150 AW984166 AW984167 AW984168 AW984179 AW984134 AW984160
AW984180 AW984194 AW984202 AW984190
413682 1527038 1 BE156943 BE157375 BE156965 BE156949BE156956
441320 589785 AI346734 AI377971 BG193341 BG548376 AA928353 AI768724 BG215700 AA449370 BI462157 BI060283 BG677508 AA318802 BG719160
408544 683260 1 AW293825AW235391
413454 1515217 1 BE141291 BE141306BE141288BE141283BE141162BE141168BE141290BE141161BE141165
444404 16136 1 BC013183 AW408658 NMJ02119 M31525 M26039 BM456399 BF732381 BM 152457 AW407685 BM193161 AW407778 BI819141 AA702254
BF855074BI761232 436063 5483.1 AK000028 AA494483 AI298674 AA720773 AV761529 AI884670 AI936202 AW294235 D61652 BF881184 AV711384 N27154 AI926970 AV734970
N40094 N28596 AA884747 AA512890 BG436593 444346 47906.14 AI147991 AH 42274 AH 98553
424281 892055 1 AA338252AA338213 423901 887384.1 AW962691 AA333006 AA332289
414991 1785136.1 D78831 C17898 D78863
411673 1096744.1 BF330730 BF350539 BE153665 BE065062 BE064650 BE064863 BF330763 BE153820 BE064737 BE155079 BE064651 AW856751 AW856622
BE064691 BE153674 BE153698 BE064730 BE153536 452203 2630 1 BC014081 NM 000593X57522 L21208 L21207 L21206 L21205 L21204 AL561404AL546423 AL560492 AL556882 AL541576 AL550654 BI823519 BI770023 AL554969 BI489906 AI304693 AW295947 BM146642 X57521 BG820143 BE898390 F06770 F12630 BM423610 AL561518 BM009470
BG742981 AA279685 AA847441 AA313737 BF172639 BF897216 BF914190 BF903647 S70277 AI569694 AW073296 AI361433 AA564644 AA487429 BE858232 AA838610 AI539114 A1719375 AI829129 BG057675 AI423422 AU158860 BE300655 AW170777 AA586956 AL571889 AL556850 AL576404 AL582800 BI256544 BF342301 BG875994 AA054458 AA353161 AI940434 BE816522 AL577636 AI479650 AW150377 AU154395 AW951271 AI032220 AI819778 A1346733 AW771150 AW512525 AI249904 AA279809 AI352549 AW512517 BG056280 AA521222 BE271141 AL581932 AL541575 BI819184 AV660190 AL556475 AI620020 AW089888 AW079179 Z21518 AA687601 F04651 AI783961 T57198
AI433367 T78652 AL554968 AA365648 AL582619 BE874601 BF804669 AL574458 BM145502 AI266514 AI538823 AI475626 AA948210 AA884054 AA487637 AA031844 AA535221 AW794256 AW361447 BE788505 AI682892 AA830989 AA862356 AA653084 BM009154 AA135727 H05927 H23433 R42244 N79997 AW366665 AW366601 AA678742 AL556474 AA135770 BE774050 BF914200 H88457 AA627746 BI560216 BI753586 458332 1139685.1 AI000341 AI766341 AW873274 431594 1236764.1 AI823999AA970060AA508176AW972585 AI873427 AW972389
414372 484211.1 BI093452 AW970865 BG118285 AA569075 AA492132 AW753140 AA213770 AA143654
459644 662385.1 W03900AW197203 AW753300
400269 2726.1 X65018 BC022318 NM_003019 BE465060 AI732255 BF446634 AI820677 AI002217 AI924488 B1821373 BI770406 BI823937 BI820265 BI489632
BG482911 AA617783 AI807697 AW205576 T94427 AA487101 T94513 BI819407 BI822450 BI820618 BI824619 BG542824 BG537862 430015 713_2 BC017171 BC012195 NM 007126AF100752AL137377Z70768 BM474865 BG754806AU124376 BG757203 BG764420 BG775028 BG824418
BM045810 AU120387 BG770238 BG686740 BG913323 BI759980 BG395998 BM048875 BE881070 BE313689 BE879144 BM309834 AW245847 AI770171 BF196861 BE856897 AA463876 AI375927 AA648810 AA948193 AA490916 AI459893 AI458188 AI240408 AI191843 AI131029AW768399 AI365196 AW337984 AW026150 BE466591 BE674599 AI818438 AA772197 AI651927 AW151143 BI198825 BG819083 BM458764 BE903567 BE732715 BM043200 BE900263 BE900706 BE731097 BE390023 BG875384 BF996406 BF988930 BM475542 AW246215 BE501897 BE903610 BE561530 BE560537 BE903782 BE732947 BI227204 BG761305 BE262642 BE391848 BE382475 BG008258 BI547991 BI459099 BE391391
BE259420 BE298109 AW245422 AI423847 AI914618 H80534 BE301004 AL531791 AI435581 BF793112 AL577303 AA373265 BE746965 BF743630 BE879296 AI359493 BM018598 AI689260 AW072450 F20201 AW151405 AW517572 AA773468 BG259694 BE391163 BG621529 AI421728 BG767231 BM462953 BG340524 W52648 AA113434 BE785431 BI041981 BG832385 BG253168 BG759470 BF369329 BF981332 BE259418 BE785738 BI091658 N72512 W58732 W85690 BG958989 Al 205206 H19721 W17051 W77958 BI262010 AA844319 W74143 W72214 N85194 BE734033 BG164099 AA931069 F13645 R41394 AK025758 BG180977 BE349455 AA812018 AA740241 AI027722 AI150356 AA886395 AW977627
BE220225 AA884082 AW518114 AI243844 AA809493 AA481029 AA825718 AI347866 AI431670 AA814436 AI251109 R07704 AA765606 AA724593 AI918399AI537550AA491103AW008188 R07703AA989120AA746235AW028983AA789102AU185751 AW971465AA489681 AW971893 AW612086 BE077936 BI860809 BE002760 BG746251 BE962912 BM454584 AL134894 BF104082 H80591 443951 MH1768.18 AI334106 R63583 AI028079 AI140098 AI911625 AI890637 F34815 T65959 N40935 W52768 AA854747 AA861945 AA878472 AA778270 W32249 AA026061 W52662 W15352 W79670 W95384 T94283 AA002155 R82052 BE825493 BE825520
413497 1518002 1 BE177661 H06215 BE144709 BE144829
434747 117643.1 AW976537 AI033582 AA837085 AA745261 AA648395
406782 0.0 AA430373 AA968771
419200 9531.1 BF036043AW190446 BG194731 AW662036 AI445021 BE937550AW818972AW393132AA834685 BF112058AV721682 H16423AI270167 A1857345AA937302AW818444 BE929780 BG498678 BF155010 BI598271 BI599811 BE161728AW578737 AW753711 AW379707AW381918
BG506608 AW028637 AW994240 BF887392 BF790073 AW381624 AV727105 BF439618 AA443174 AI018009 N42850 AW573242 AI417258 AA463483 AI676131 AH67170 AA836627 AA443828 AW592922 AA235129 AA730278 AW439062 AW474332 BI043239 AW474342 BG708553 AW362423 BF090028 BE827256 R16550 R39478 R39479 R94368 BG540916 BM314745 AA251087 D54231 D55274 BF085805 D31589 AW966405 AW994425 D81879 BE093545 AW901107 AA383529 BI021552 R56420 N39976 AA573281 H82595 AA234955 BE093539 AW367006 BF358697 BF366318 AA663856 BE702099 BF035969 AI267384 AI267232 BE348320 AA621574 AA861212 BF083343 BF083341 AV745131 D53074
AW954476 AW954472 AA376836 AV724531 D53063 C14928 AA093287 AA062638 BG483558 BE940050 AA765954 T70171 BE938775 BE940057 D53502 AW373300 AL118798 B 128728 AA193411 AW444709 AW952455AI887612 BF431948 BI496876AI264159 BM128481 AI624657 AI689301 AI969467 AA861685 AA251595 AA625761 AA872090 AI826790 AA328366 BE827416 R75951 D56918 R68122 BE827384 AL118797 AI184164 AA164411 BI495332 BE858113 AI863860 H00660 T69849 AW780389 C14667 BE934995 BI018652 R92801 AA164410 H00752 AW373305 AW373299 AW373302
438089 22448 4 BM475665 BE644917 AW770789 AW952971 N64863 B 263259 A1224545 Al 184866 N69114 AW518902AI440169AA809472AV654440
AA281642AU185230AW337382AI872923AI537113 N73882T83378 H63731 BF671764 AW897824AI811204AA344646 BE009112 BG899664 H91240 R60548 N41701 438091 22448 1 AK054860AV652198AV652192AV652138AV652127AV652194 BE935919AV652017AV651995AV651548AV646063AV651985AV646184 AV646179 AW880409 AA345002 BF155189 BE068931 X56197 AL603014 AW953629 BM263546 BE550772 AA701084 AI681352 AA358689
AW938841 BF438147 W05391 H75313 BF326185 AV646335 AV651589 AV646340 AV651992 AV646384 AV646364 AV687497 BF155183 AV646370 AW797876 AI906821 X56196 BE833835 AA628440 BE833808 BF224205 AA709126 BE673807 AI923886 AA947932 AI276125 AI185720 AW510698 AA987230 BE467708 AW898628 AW898544 AI146984 AW043642 AI288245 AI186932 AI635262 AI139455 AI298739 AI813854 AI024768 BE699445 BE699444 AI707807 D52654 AI214518 AI004723 AI698085 AW087420 AI565133 AA845571 AW898622 BF110144 AW513280 AI061126 BF362770 AI268939 AI435818 BF475318 AI024767 BE174213 AA757598 AA513019 AA902959 AI860794 AI334784 BF108411
BM310532 AW513771 AI951391 AI337671 BF095606 BF095601 BF095468 AW890091 BF095753 AW243400 AW898607 AW898616 BF362762 AI922204 AW898625 BE699468 BE174196 AW102923 D52715 BE699456 D52477 D55017 BF955933 BG623563 AV646254 AA463522 BI003244 AI299190 W40186 BE174210 BF939091 BF434180 AW579001 T55662 H01811 T52522 BF945037 BF955938 D54679 D53933 R67100 BG925552 BF999056 R83430 Z29922 T85791 W03942 H63289 AI091537 BF086583 AA345570 H48870 H80720 T83523 BI039626 BI037700 R00353 BF155184 N98343 N79072 H01812 T55581
TABLE 35C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham et al " refers to the publication entitled "The DNA sequence of human chromoεome 22" Dunham etal (1999) Nature 402489 495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 402550 7652009 Minus 80413 80673 403244 7637828 Plus 175792 176144 405452 7656638 Minus 93876-94275 401447 8574299 Minus 65053-65283
405097 8072599 Plus 171191-171360
400712 8118874 Plus 36087-36268
403478 9858258 Plus 116458-116564
405827 7109593 Plus 10279-10972
405075 7770506 Minus 124680 125321
406267 7528342 Minus 2570 2731
402240 7690131 Plus 104382-104527,106136 106372
404811 3702428 Plus 26424-26596 28854-28987
403589 8101229 Plus 5-330
404088 9958257 Plus 184131-184295
401897 8569218 Plus 604-767
405453 7656675 Minus 83710 83980
402516 9798099 Minus 195342-195511
406266 7528342 Minus 2365-2518
404696 9800109 Minus 60037-60144,62675-63081
403533 8076874 Plus 162922-163658
406303 8575868 Plus 173622-173786
404240 5002624 Minus 116132-116407,116653-116922
404056 3548785 Plus 75843-76980,77146-78263
402736 9212044 Minus 66876-67010
405545 1054740 Pluε 118677-118807,119091-119296,121626-12182
405441 7408124 Plus 100952-101283
400680 8118752 Plus 118343-118684,120720-121013
404277 1834458 Minus 91665-91946
404854 7143420 Plus 14260-14537
TABLE 36A About 52 genes upregulated in non spxific interstitial pneumonitis relative to hypersensitivity pneumonitis or idiopathic pulmonary fibrosis
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number UnigenelD Unigene number Unigene Title Unigene gene title
R1 90th percentile of NSIP Als divided by 90th percentile of HP Als, where the minimum value for the numerator and denominator was set to 50
R2 90th percentile of NSIP Als divided by 90th percentile of IPF Als, where the minimum value for the numerator and denominator was εet to 50
Pkey ExAccn UnigenelD Unigene Title R1 R2
435140 AA668123 Hε 134170 ESTs 276 276
429504 X99133 Hε 204238 lipxalin 2 (oncogene 24p3) (NGAL) 257 1 00
435375 AI733610 ESTs 255 255
420813 X51501 Hs 99949 prolactm induced protein 255 1 35
425071 NM 013989 Hs 154424 deiodmaεe, lodothyronme type II 252 073
421296 NM_002666 Hs 103253 peπlipm 250 245
419290 AI128114 Hs 112885 εpmal cord-derived growth fxtor-B 243 1 79
408882 H12084 Hs 31110 ESTε, Weakly similar to MAGE-B4 [H sapie 242 1 77
437318 AW362939 Hs 120721 ESTs 236 1 61
421823 N40850 Hs 28625 ESTs 229 056
412228 AW503785 Hs 73792 complement component (3d/Epsteιn Barr vi 228 089
430536 AI809163 Hs 9908 nitrogen fixation cluster-like 225 280
414009 R67516 ESTs 219 1 86
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontin, 219 033
430699 AW969847 Hs 292718 ESTε, Weakly similar to RET2JHUMAN RETIN 218 1 24
413722 BE247354 Hs 16400 ESTs, Weakly similar to KIAA1435 protein 214 1 95
433874 AW204429 Hs 155033 ESTs 213 1 72
429609 AF002246 Hs 210863 cell adhesion molxule with homology to 212 091
414290 AI568801 Hs 71721 ESTs 211 081
451678 AA374181 Hs 26799 DKFZP564D0764 protein 211 1 01
406785 AA588061 gb nk10d03 s1 NCI_CGAP_Co2 Homo sapiens 210 1 61
449048 Z45051 Hs 22920 similarto S68401 (cattle) glucose indue 208 085
444179 W35132 Hs 267442 ESTs 208 1 13
430223 NM 002514 Hs 235935 nephroblastoma overexpresεed gene 205 080
451099 R52795 Hs 25954 interleukin 13 rxeptor, alpha 2 204 079
439134 AA830599 ESTε 204 1 89
418512 AW498974 dixylglycerol kinaεe, zeta (104kD) 202 202
457311 AI497811 Hs 172753 Homo εapiens chromosome 19, BAC 41195 (C 200 1 45
402274 C19000498* gι|4567179|gb|AAD23607 1|AC00 1 88 224
453222 AA033929 Hs 19156 ESTs 1 77 200
447261 NM.006691 Hs 17917 extracellular link domain-containing 1 1 73 202
427297 AW292593 Hs 334907 Homo sapienε, clone MGC 17333, mRNA, com 1 69 1 69
406714 AI219304 Hs 266959 hemoglobin, gamma G 1 62 247
418333 W92113 gb zh48e01 r1 Soareε_fetal_lιver_spleen_ 1 59 204
404090 Target Exon 1 48 203
444445 AA342329 Hs 115920 Homo sapienε cDNA FLJ22816 fis, clone K 1 39 206
414386 X00442 Hs 75990 haptoglobm 1 09 1 44
439372 AF088033 Hs 159225 ESTs 1 05 213
432606 NM_002104 I Hs 3066 granzyme K (seπne protease, granzyme 3, 1 01 208
412472 AW975398 Hs 293836 ESTs 1 00 226
432894 AW167668 Hs 279772 brain spxific protein 097 1 19
422060 R20893 Hs 325823 ESTs, Moderately similar to ALU5_HUMAN A 096 206
416971 R34657 Hs 80658 uncoupling protein 2 (mitochondnal, pro 095 1 08 424310 AA338648 Hs 50334 testes development related NYD SP22 093 1 47
422109 S73265 Hs 1473 gaεtπn releasing peptide 092 305
420440 NM 002407 Hs 97644 mammaglobin 2 091 211
418196 AI745649 Hs 26549 KIAA1708 protein 090 225
418707 U97502 Hs 87497 butyrophiliπ subfamily 3, member A2 089 1 11
419231 AL046294 Hs 136245 ESTs, Weakly similar to T17227 hypotheti 085 1 74
446608 N75217 Hs 257846 ESTs 082 210
418918 X07871 Hs 89476 CD2 antigen (p50), sheep red blood cell 073 1 32
412610 X90908 Hs 74126 fatty acid binding protein 6 ileal (gas 070 1 76
TABLE 36B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT Number Accession
435375 130020 1 AI733610 AI049989 AA678769
414009 438978 1 BE221268 R67515 AV730582 R67516
406785 0 0 AA588061
439134 2581476 1 AA830599 AA970659 AA883802
418512 12225 6 BM046773 AA224297 T33786T08951 T09274 T08592 T30936 AA350905
418333 73080 1 AF264624 AW668618 AV731446 R93353 AA584550 AV732728 BF802614 BF434359 AA077092 BI027317 AA199812 AW629027 AA831618 AI124782
AA765804 AA055698 AA677404 AA055366 AA889402 AA765530 BE503126 BE467367 AW139964 W81697 AI887846 W81696 AA447817 AA447667
F13631 BF055573 AW268271 AW088477 BF677839 AL601859 AW502118 AW502624 AA574189 BI020104
TABLE 36C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in thiε column are Genbank Identifier (Gl) numberε "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
402274 2935596 Plus 5604-6527 404090 9967460 Minus 100815-100966
TABLE 37A About 206 genes downregulated in lung fibrosis relative to normal lung
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accesεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of normal lung Als divided by the median of IPF Als, where the minimum value for the numerator and denominator was set to 50
Pkey ExAccn UnigenelD Unigene Title R1
454229 AW957744 Hs 278469 Ixπmal proline rich protein 11 67
432128 AA127221 Hs 296502 ESTs 986
421218 NM.000499 Hs 72912 cytxhrome P450, subfamily I (aromatic c 7 69
453310 X70697 Hs 553 solute camerfamily 6 (neurotransmitte 732
420958 AA309431 Hε 66 interieukin 1 rxeptor-hke 1 7 13
402608 Homo sapiens defensm, alpha 1, myeloid- 667
406714 AI219304 Hε 266959 hemoglobin, gamma G 540
406673 M34996 Hε 198253 major histxompatibility complex, clasε 5 22
416539 Y07909 Hs 79368 epithelial membrane protein 1 504
418021 M15881 Hs 1137 uromoduhn (uromucoid, Tamm-Horεfall gly 477
409385 AA071267 gb zm61g01 r1 Stratagene fibroblast (937 474
450847 NM.003155 Hε 25590 stannixalcm 1 446
404518 CD83 antigen (xtivated B lymph∞yteε, i 436
413951 AW051200 Hε 75640 natπuretic peptide prxurεor A 432
407570 Z19002 Hs 37096 zinc finger protein 145 (Kruppel-like, e 425
456525 AW468397 Hs 100000 S100 calcium binding protein A8 (calgran 423
429509 AW614420 Hs 204354 ras homolog gene family, member B 414
445769 AI741471 Hs 23666 ESTs 410
414002 NM 006732 Hs 75678 FBJ munne osteosarcoma viral oncogene h 406
425571 AJ007292 Hs 158306 ephπn A2 392
423168 R34385 Hs 124940 GTP-bind g protein 380
401234 mitogen-activated protein kinase 8 inter 378
402181 Target Exon 377
403479 NM.007064 Homo sapiens serme/threonine 368
435424 AW083883 Hs 37896 Homo εapienε cDNA FLJ13510 fis, clone PL 368
402911 NM_021158* Homo sapiens protein kinase d 366
442195 NM.001430 endothelial PAS domain protein 1 3 65
400089 Eos Control 360 413948 C05145 Hε 75636 myosin light chain 2a 356
438564 AA381553 Hs 198253 major histocompalibility complex class 3 54
413956 AI821351 Hs 193133 ESTs, Weakly similar to ALU7 HUMAN ALU S 354
431319 AA873350 Hs 302232 ESTε 352
434292 AF124368 Hs 306551 Homo sapiens IMAGE Consortium ID 839832, 348
401540 NM.002675 Homo sapienε promyelxytic leu 346
426477 AA379464 Hs 154073 gb EST92386 Skin tumor I Homo sapiens cD 343
402328 Target Exon 342
401590 Target Exon 342
403645 NM_024513* Homo sapiens FYVE and coiled- 337
403376 Target Exon 3 36
447966 AA340605 Hs 105887 ESTs, Weakly similar to Homolog of rat Z 3 35
417696 BE241624 Hs 82401 CD69 antigen (p60, eariy T-cell xtivati 3 28
413719 BE439580 Hs 75498 εmall inducible cytokine εubfamily A (Cy 3 27
401126 NM_006856* Homo sapiens activating trans 3 27
408243 Y00787 Hs 624 interleukin 8 323
412429 AV650262 Hs 75765 GR02 oncogene 3 22
426420 BE383808 Hs 322430 NDRG family, member 4 3 21
449338 H73444 Hs 394 adreπomeduilm 319
401904 Target Exon 316
401919 NM 012448* Homo sapienε εignal transduce 3 14
406443 ENSP00000236574* Hypothetical 21 8 kDa p 314
458232 BE217872 Hε 279537 ESTs 3 12
406016 Target Exon 3 12
450912 AW939251 Hs 25647 v-fos FBJ murine oεteoεarcoma viral onco 311
451831 NM 001674 Hs 460 activating transcription factor 3 308
450562 AW136468 Hs 202199 ESTs 307
405938 Target Exon 304
451029 AA852097 Hs 25829 ras related protein 302
421201 AW241940 Hs 102500 hypothetical protein FLJ20481 298
439839 AA889354 ESTs 298
439891 AL389940 Hs 109968 ESTs 296
418935 T28499 Hs 89485 carbonic anhydrase IV 295
418853 NM 005236 Hs 89296 excision repair crosε-complementiπg rode 295
429113 D28235 Hs 196384 proεtagland endoperoxide synthase 2 (p 294
410326 AI368909 Hs 47650 ESTs 2 88
407244 M10014 fibrinogen gamma polypeptide 285
459721 AI299050 Hs 143835 gb qn14d12 x1 NCI CGAP_Lu5 Homo sapiens 284
416212 R40290 Hs 124685 ESTs 284
428686 AA431801 Hs 98764 ESTs, Weakly similar to A29861 actm gam 283
437508 AI204354 Hs 121347 ESTs 282
437990 AI686579 Hs 121784 ESTs 2 82
443709 AI082692 Hs 134662 ESTs 281
423099 NM 002837 Hs 123641 protein tyrosine phosphatase, rxeptor t 2 80
416188 BE157260 Hs 79070 v-myc avian myelxytomatosiε viral oncog 279
404231 Target Exon 278
434305 AI018280 Hs 130189 ESTs 277
445493 AI915771 metallothionein 1E (functional) 276
418056 AA524886 gb nh34f02 s1 NCI_CGAP_Pr3 Homo εapienε 276
404102 Target Exon 275
440206 AI762232 Hs 46794 ESTε 275
403031 cathepsin D (lysosomal aspartyl protease 275
413164 BE068494 gb MR1-BT0371-050500-009-a12 BT0371 Homo 274
459330 016931 gb C16931 Clontxh human aorta polyA mRN 274
456967 AW004056 Hε 168357 T-box 2 274
427602 AI375258 Hε 98005 ESTs 274
431367 Z20964 Hε 323817 DKFZP547E1010 protein 272
406059 Target Exon 271
420575 BE263301 Hε 99029 CCAAT/enhancer binding protein (C/EBP), 271
457275 AA463422 Hs 209431 ESTs 271
432559 AW452948 Hs 257631 ESTs 271
402483 NM 020389 Homo sapiens putative capacita 270
416069 R37101 Hs 20982 ESTs 270
445445 AF238870 Hs 275706 Homo sapiens clone GLSH-3 similar to gli 269
436232 AA707006 Hs 187863 ESTs 268
418773 T39748 Hs 325474 Target CAT 267
434038 AA622104 ESTs 267
405448 Homo sapienε mRNA, cDNA DKFZp586l2022 (f 266
404439 ENSP00000067222* Mitxhondπal 28S πbos 265
435724 N39308 Hs 117898 ESTs 265
404026 Target Exon 265
400881 NMJJ25080 Homo sapienε hypothetical prot 264
430314 AA369601 Hs 239138 pre-B-cell colony-enhancing factor 262
405429 Target Exon 262
402642 C1002296 gι|6677817|ref|NP_033126 1| rep 261
438575 BE304709 Hs 146550 myosin, heavy polypeptide 9, non muscle 261
449293 AA001088 Hs 29739 ESTs, Weakly similar to C34323 GTP-bindi 261
416157 NM 003243 Hs 342874 transforming growth factor, beta rxepto 260
446122 AI362790 Hs 278639 KIAA1684 protein, likely homolog of mous 259
433291 AF007191 gb Homo sapiens SIB 276 intestinal mucin 259
426795 AI810474 Hs 196945 ESTs 258
423503 M92843 Hs 343586 zinc finger protein homologous to Zfp-36 258
430768 AB030207 Hε 247888 guanine nucleotide binding protein 13, g 258 423387 AJ012074 vasoactive intestinal peptide receptor 1 257
442681 AI809182 Hs 130907 ESTs 257
408652 R43409 Hs 6829 Homo sapiens mRNA for KIAA1644 protein, 256
402217 C19001662* gι|6753872|reflNP_034345 1| I 256
427700 AA262294 Hs 180383 dual specificity phosphatase 6 256
455674 BE065941 gb RC3-BT0319-100100 012-d12 BT0319 Homo 256
457831 AA706937 Hs 120802 ESTs, Moderately similar to A26641 Na'ex 256
454219 X75042 Hs 44313 v rel avian reticuloendotheliosis viral 255
458648 AW444551 Hs 35380 x 001 protein 255
456663 BE251104 Hs 113052 RNA cyclase homolog 254
440178 AW502463 Hs 196521 ESTs 253
457139 AI557280 Hs 184270 capping protein (actiπ filament) muscle 252
405857 Target Exon 251
410204 AJ243425 Hs 326035 early growth response 1 250
412851 A1826502 Hs 97269 ESTs 249
419968 X04430 Hs 93913 interleukin 6 (interferon, beta 2) 249
409209 AA460160 Hs 73217 ESTs 249
447173 AW449385 Hs 157294 ESTs 248
440034 AI908639 Hs 246781 ESTs 244
418168 R85350 Hs 101368 ESTs 243
417295 AW993524 Hs 43148 epithelial membrane protein 1 243
406305 transcriptional adaptor 3 (ADA3, yeast h 242
427886 AA417083 Hs 104789 ESTs 242
436409 AJ238982 Hs 183656 VNN3 protein 242
413861 BE175424 gb RC4-HT0578-170300-012-d01 HT0578 Homo 240
403605 C3000142* gι|4503015|ref|NP 003900 1| co 237
402594 C1002603* gι|9887091|gb|AAG017381|AF248 237
402803 NM.001397 Homo sapiens endothelin coπver 237
428336 AA503115 Hs 183752 microsemmoprotem, beta- 236
458568 AI769067 Hs 127824 ESTε, Weakly similar to T28770 hypotheti 236
442630 AW572938 Hs 130580 ESTs 235
409368 AA071059 gb zm66a10 r1 Stratagene neuroepithelium 233
405156 NM.003213* Homo sapiens TEA domain famil 231
448162 AL039531 Hs 323363 hypothetical protein FLJ22169 231
403591 Target Exon 231
406193 Target Exon 230
420813 X51501 Hs 99949 prolactin induced protein 230
442941 AU076728 Hs 8867 cysteine rich, angiogenic mducer, 61 228
400703 C11001794* gι|10946612|ref|NP 067286 1| 227
415026 AA159356 Hs 72308 ESTε 225
400334 Y13187 Homo εapienε dmd gene, intron 11 2 18
445878 AI262974 Hs 145587 ESTε 218
404975 uncharacteπzed hypothalamus protein HT0 218
436370 R01220 Hs 185679 ESTs 217
400513 Target Exon 216
424008 R02740 Hs 137555 putative chemokine rxeptoπ GTP-bindmg 215
415405 R59141 gb yg96d11 r1 Soares infant brain 1NIB H 215
407612 U26403 Hs 37142 ephπn-A5 212
409837 AW501504 gb UI-HF-BPOp-ajd h 04-0-UI r1 NIH_MGC_5 208
458637 AV657446 gb AV657446 GLC Homo εapiens cDNA clone 207
449125 AI671439 Hs 196029 Homo sapiens mRNA for KIAA1657 protein, 200
418922 AW956580 Hs 42699 ESTs 198
402404 NM.024967* Homo sapienε hypothetical pro 1 98
421993 R22497 Hs 110571 growth arreεt and DNA-damage-inducible, 198
413731 BE243845 Hs 75511 connxtive tisεue growth factor 1 96
456855 AF035528 Hs 153863 MAD (mothers against dxapentaplegic, Dr 1 96
428193 NM 004235 Kruppel-like fxtor 4 (gut) 1 93
422166 W72424 Hs 112405 S100 calcium binding protein A9 (calgran 192
439453 BE264974 Hs 6566 thyroid hormone rxeptor interxtor 13 1 92
433883 AI925688 Hs 222312 ESTs 191
406564 msh (Drosophila) homeo box homolog 2 1 91
403581 Target Exon 1 90
403716 Target Exon 1 90
404758 Target Exon 1 90
439500 W73158 Hs 170434 Homo sapiens cDNA FLJ 14242 fis, clone OV 1 89
448793 AI864581 ESTs 1 84
435857 AF253468 Hs 3736 delta-like 4 homolog (Drosophila) 1 83
426653 AA530892 Hs 171695 dual spxificity phosphataεe 1 1 82
402051 Target Exon 1 81
409859 AW501926 gb UI-HF-BROp-ajp-f 08 0-UI r1 NIH.MGC.5 1 78
417967 BE244373 Hs 1119 nuclear receptor εubfamily 4, group A, m 178
405063 Target Exon 1 78
405163 C5000561* gι|7513700|pιr||T14151 Inv pro 1 75
402386 Target Exon 1 73
406755 N80129 Hs'199263 metallolhioneiπ 1L 173
409811 AW500896 gb UI-HF-BPOp-aιr-a-03 0-UI r1 NIH.MGC.5 1 70
454034 NM_000691 Hs 575 aldehyde dehydrogenase 3 family, member 170
400489 Target Exon 1 70
428704 AA432007 Hs 192090 ESTs 1 69
429307 AU076592 Hs 198951 jun B proto-oncogene 1 67
400116 Eos Control 165
404795 Target Exon 1 65
408053 AW139474 Hs 246862 : ESTs 1 65 414580 BE386918 gb 601275386F1 NIH.MGC.20 Homo εapienε c 1 63
428800 M57627 Hs 193717 interleukin 10 1 63
451676 R84770 Hs 33538 ESTε, Weakly similar to oxygen regulated 1 62
402394 Target Exon 1 61
404818 Target Exon 1 60
436364 X06096 gb Human macrophage alphal-antitrypsm c 1 55
420369 U96769 Hs 97220 chondroadheπn 1 54
405590 CX001497* gι|4557543|ref|NP_001384 1| ex 1 54
402448 Target Exon 1 53
433495 AW373784 Hs 71 alpha 2-glycoproteιn 1, zinc 1 51
409020 AA062549 Hs 21162 retbindin 1 51
405443 Target Exon 1 12
TABLE 37B
Pkey Unique Eoε probeset identifier number
CAT number Gene cluster number Accession Genbank accesεion numberε
Pkey CAT Number Acceεεion
409385 110758.1 T65940 T64515 AA071267 AA071334 442195 15007.1 U81984 NM_001430 BE907085 BI333232 AI021986 AU138476 C18601 U51626 AU100517 BI054387 AU076970 BE786454 BG010080 AW377189
BF998789 AA368139 R11396 T83613 BG006324 BI012404 BG001643 BF757957 AL549361 AL544018 BE002870 BE929314 BE090199 AL046650
BI053717 BE929315 BI054967 BF960055 BF925432 R05421 BF922073 T70331 BI004403
439839 2594580.1 AI023587 AA889354 AA846791 445493 423456.1 AV711317 AI809938 AI808768 AI240593 AI915771 418056 286199 1 AW971347 AA524886 AA211537 BF903005 BF357120 413164 1492512.1 BE068758 BE068745 BE068689 BE068778 BE068529 BE068683 BE068445 BE068392 BE068719 BE068473 BE068521 BE068628 BE068422
BE068618 BE068354 BE068390 BE068414 BE068433 BE068369 BE068384 BE068661 BE068324 BE068301 BE068436 BE068754 BE068329
BE068672 BE068494 BE068596 BE068332 BE068347 BE068588 BE068328 BE068493 BE068740 BE068685 BE068759 BE068307 BE068429
BE068303 BE068693 BE068374 BE068295 BE068625 BE068302 BE068663 BE068675 BE068579 BE068311 BE068674 BE068547 BE068602
BE068605 BE068352 BE068306 BE068401 BE068537 BE068552 BE068450 BE068723 BE068393 BE068671 BE068748 BE068317 BE068447
BE068568 BE068632 BE068357 BE068330 BE068498 BE068631 BE068540 BE068410 BE068626 BE068591 BE068522 BE068676 BE068499
BE068361 BE068598 BE068350 BE068299 BE068580 BE068567 BE068692 BE068321 BE068327 BE068739 BE068526 BE068538 BE068765
BE068340 BE068733 BE068293 BE068565 BE068480 BE068476 BE068761 BE068712 BE068706 BE068549 BE068419 BE068383 BE068434
BE068418 BE068525 BE068543 BE068752 BE068550 BE068623 BE068470
459330 105725 1 BG563152 BF846777 BF849354 BF849359 BF846636 BF849201 BF849356 C16931 AA056717 AW864542 AW882724 AA056567
434038 630986 1 AI910738 AW139227 AA932891 AA622104
433291 73706 1 AF007191 AW820706 BG978594 BF872238
423387 2612.2 L13288 AA928785 AI608912 AW872978 AA565655 AI022915 AI304920 AI564366 AI668793 AI094557 T60038 R72302 H45409 AA508805 R46356
AA418798 BM129553 BM129126 BM129292 BM128865AI808418 AI689932AI806573 BF431808AW872985 AW166269 H73241 T16182 AI264547
R73391 R72085 R72840 T83751 X75299 BF754348 R94105 AW449839 R73300 NM 004624 AI797007 BE045543 BF110021 BF754250 T83923
AW884084 AA903896 AA418962 L20295 R72351 H45098 AA961010 R73210 R46451 AW884085 BI022902 BI763932 BI910138
455674 1490762 1 BE065941 BE065997 BE066003 BE066070 BE066098
413861 1561647 1 BF352282 BE175424 BE175418 BE175383
409368 110612 1 AA071059 AA085201 AA085020
415405 1872126 1 W18191 R59141 R54142 R12130 F11362 Z42794 F08242 F07925 H21084 R54090 R59142
409837 915621 1 AW501504 AW501656 AW503048 AW502449 AW502098
458637 395206 1 AV657752 AV657446
428193 430.1 AF105036 U70663 NM_004235 AF022184 AU141767 AU141110 AL040569 D44830 BI011351 AL575805 AI290876 AI014784 AI393429 AI266211
AW074303 AA620711 BF197792 AW008766 D25944 AI687397 AA621680 AV714408 BF446905 BM314505 BF514079 BM314197 AA845201
AW874084 BE720622 AI127241 AA236239 AI679709 AI679135 AI572470 AA573434 AI568487 BE049325 AA687950 BG925989 AI338031
AI365073 AI024576 AA298805 H04001 H45668 BG682146 AL552388 BI462361 BG547513 BG896863 BI256661
448793 3006936 1 AI936948 AI864581 AI570641
409859 916430 1 AW501926 AW502566 AW501927
409811 58948 2 AK057581 AW500962 AW500896 AW501105
400116 5269 1 D42041 NM.014610 AJ000332 BI758702 BG720650 AU141129 AU130711 AU141380 AU132402 BM048556 AU127520 BE259984 AU128952
BE614151 AL601516 BM146777 AU128103 BM194094 BE937951 BE696396 AK026897 AK026567 BF969293 BE798100 BI086881 BG166248
BE877845 BG385414AW886747 BF093789 AW390159 BF820311 AA421676 AW880845AW404827 BF726465 BE161190 BE254102AW406002
BE161223 AI912055 BF930228 AW374357 AW794531 BE720524 BE933982 BE933658 BE933694 BE933978 BE933654 BE933583 BE166557
BE933874 BE933641 BE933859 BE933626 BE933866 BE933633 BE933864 BE933631 BE933867 BE933634 BE933857 BE933624 BE933883
BE933650 BE720491 AA420426 BE720410 BE720458 BE720444 BE720411 AW368748 BF874616 BE933498 BE835979 BF926667 AW849921
AW850026 AW850022 AW849977 AW849900 BG250251 W87689 AI192825 AI692824 AA426263 AI090315 AI309537 AA877437 AA478438
AI538868 AW276162 AI279916 AA600318 AI188836 AW662284 AI262619 AA293457 BF347442 AA421677 AA658063 AA565510 AA937060
AI142684 AA788940 AA827426 AU152614 AI342784 AU148738 AA219664 AA047835 H99450 AA018563 AI073634 BM475120 BG875251
BG248778 U46372 AA383858 AU 140356 BG821891 BF935049 BI760656 BI054103 BF982309 BE872215 BI257291 AU 158469 AU 160599
AU152469 AU152375 AU152059 AU148575 N32267 AU149554 AI627459 AI719840 AW779017 AI291493 AW304181 AW470055 AI086491
AI311387 AI634232 AI151241 AI288848 AW050588 AW589580 AI241353 AI880219 AA039309 AA026517 AA016238 AA013444 H86822 R87530
AA058462 N27082 Z39679 BE544309 W52619 AA018076 AI813668 AW189907 AI418104 AU159878 AU150087 R21754 AA015932 H67274
AU153097AI961344 AA018208 W32429 R45344 R77453 BM470129AU130415 BI227374 BE298179 AW844963AW844883 AI904066AA379006
BF850571 AA355641 BG747156 AL547262 AW367941 BE560004 BI116061 BG899031 BE560318 BF174177 BI051456 BE001967 BE386446
BF969326 BF808765 BF684480 BG421617 AI940607 AW875483 BE789632 BF808711 BI192691 AW904249 BI911430 BE265407 BE730343
BE397808 BI226516
414580 623093.1 BG333973 BE385437 BE408833 BE387650 436364 1414.37 X05826 X06096 BG468890 AW951851 W23562 T28392 H56742 H58030 T69205
TABLE 37C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numbers in thiε column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
402608 9910096 Plus 37495-37669
404518 8151988 Plus 84494-84603
401234 9929642 Plus 120173-120337
402181 8575912 Plus 449746-450040
403479 7329292 Minus 148369-148533,150678-150809
402911 7263904 Plus 142689-142979
401540 8072433 Plus 106838-107310
402328 4464283 Minus 13758-13922,14558-14752
401590 9966320 Minus 33547-33649
403645 8699714 Minus 4433-4582
403376 9369545 Minus 108698-108830
401126 8699701 Minus 68290-68487
401904 8671966 Plus 60959-61603,62670-62890,63778-63838
401919 9502466 Plus 67536-67666
406443 9280765 Plus 85951-87327
406016 8272661 Plus 41341-41940
405938 6758795 Minus 166671-167411
404231 8218035 Minus 61077-61322
404102 7229900 Plus 97685-98018
403031 7768597 Minus 1308-1416
406059 9103984 Minus 13856-14004
402483 7574980 Minus 6557866119
405448 7582529 Plus 136347-136532
404439 7139680 Plus 55316-55585
404026 7582549 Minus 79674-79968
400881 2842777 Minus 91446-91603,92123-92265
405429 7321905 Minus 51577-51723
402642 9958129 Minus 125599-125756
402217 9795981 Minus 21521-21757
405857 6758728 Plus 26564-26819
406305 8575869 Plus 108239-108386,112216-112378,115388-11557
403605 6862654 Plus 91614-91718
402594 7705170 Plus 103082-103414
402803 3287156 Minus 55923-56033
405156 9966228 Plus 146733-146860,147899-147961,153127-15325
403591 8101229 Plus 4201-4833
406193 7289992 Plus 30183-30662
400703 8118859 Plus 63657-63857,64802-64905
404975 3419864 Minus 86096-86605
400513 9796593 Plus 74613-74823
402404 3970932 Plus 53154-53280
406564 7711604 Minus 52788-53013
403581 8101182 Plus 6794-7396
403716 7239669 Plus 86899-87122
404758 7706327 Minus 130204-130806
402051 8082020 Minus 19346-19480,20041-20119
405063 7658414 Minus 111047-111666
405163 9966267 Minuε 161171-161299
402386 9799769 Plus 22069-22303
400489 8954013 Plus 131475-131652
404795 4826439 Plus 147501-147780
402394 9929690 Plus 33308-33482
404818 2769655 Plus 33671-33839
405590 6960456 Plus 90492-90818
402448 9796640 Pluε 112942-113069,114303-114521
405443 7408143 Pluε 90716-90887,101420-101577
TABLE 38A About 207 genes upregulated in lung fibrosis relative to normal tissues
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xceεεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of lung fibrosis Als divided by 70th percentile of normal tissue Als, where the minimum value for the numerator and denominator was set to 50
Pkey ExAccn UnigenelD Unigene Title R1
437275 AW976035 Hs 292396 ESTs, Weakly similar to A47582 B-cell gr 428
407891 AA486620 Hs 41135 endomucιn-2 414
414020 NM.002984 Hs 75703 small inducible cytokine A4 (homologous 407
410219 T98226 Hs 171952 occludm 396
434666 AF151103 Hs 112259 T cell receptor gamma Ixus 388
425009 X58288 Hs 154151 protein tyrosine phosphatase, receptor t 387
406617 Target Exon 376
420568 F09247 Hs 247735 protxadheπn alpha 10 370
425873 NM.013390 Hs 160417 transmembrane protein 2 369 438797 C16161 Hs 283040 hypothetical protein PR02543 3 68
410315 AI638871 Hs 152519 Homo sapienε cDNA FLJ22524 fiε clone H 365
446714 W73818 Hs 110028 ESTs 3 64
412326 R07566 Hs 73817 small inducible cytokine A3 (homologous 361
430259 BE550182 Hs 127826 RalGEF-hke protein 3, mouse homolog 358
412790 NM 014767 Hs 74583 KIAA0275 gene product 3 56
424338 W78816 Hs 49943 ESTs, Weakly similar to S65657 alpha 1 C- 356
412654 AI093480 hypothetical protein FLJ 11896 356
414386 X00442 Hs 75990 haptoglobin 354
451035 AU076785 Hs 430 plastm 1 (I isoform) 352
436473 AI193122 Hs 132275 ESTs 3 51
406714 AI219304 Hs 266959 hemoglobin gamma G 346
414586 AA306160 Hs 16488 lymphocyte cytosolic protein 1 (L-plasti 345
427274 NM 005211 Hs 174142 colony stimulating factor 1 receptor, fo 345
427527 AI809057 Hs 153261 immunoglobulin heavy constant mu 3 39
452813 U54727 Hs 191445 ESTs 336
442831 AI798959 Hs 131686 ESTs 3 35
427774 AA278583 Hs 180737 Homo sapienε clone 23664 and 23905 mRNA 3 34
445330 R52656 Hs 21691 ESTs 331
436001 AW903849 Hs 173840 HUEL (C4orf1) interacting protein 331
431681 AK000378 Hs 267566 hypothetical protein FLJ20371 3 29
432314 AA533447 Hs 312989 ESTs 328
435129 AI381659 Hs 267086 ESTs 3 28
407151 H25836 Hs 301527 ESTs, Moderately similar to unknown [H s 324
422607 Z45471 Hs 118684 stromal cell-deπved factor 2 321
421205 AL137540 Hs 102541 netπn 4 320
428582 BE336699 Hs 185055 BENE protein 320
423582 BEO0O831 Hs 23837 Homo sapiens cDNA FLJ11812 fis, clone HE 3 19
424880 NM 000328 Hs 153614 retimtis pigmentoεa GTPase regulator 317
421233 AA209534 Hs 284243 tetraspan NET-6 protein 3 17
429350 AI754634 Hs 131987 ESTs 3 16
428727 AF078847 Hs 191356 general transcnption factor IIH polype 316
434850 Z43161 Hs 283714 30 kDa protein 313
414602 AW630088 Hs 76550 Homo sapienε mRNA cDNA DKFZp564B1264 (f 3 12
446506 AI123118 Hs 15159 chemokine-like factor, alternatively spl 311
416114 AI695549 Hs 183868 glucuronidase, beta 3 10
435869 AF255910 Hs 54650 junctional adhesion molecule 2 309
444212 AW503976 Hs 10649 basement membrane induced gene 308
422442 AA324998 Hs 147066 signal transducer and xtivator of trans 3 08
442870 N45018 Hs 8769 hypothetical protein DKFZp761J17121 308
424456 AA341017 Hs 25549 hypothetical protein FLJ20898 307
429673 AA884407 Hs 211595 protein tyrosine phosphataεe, non rxept 3 07
445107 AI208121 Hs 147313 ESTε, Weakly similar to 138022 hypotheti 306
438828 AL134275 Hs 6434 hypothetical protein DKFZp761F2014 304
428106 BE620016 Hs 182470 PTD010 protein 304
428403 AI393048 Hs 326159 leucine πch repeat (in FLU) interxtin 304
431830 Y16645 Hs 271387 small inducible cytokine εubfamily A (Cy 303
417512 X76534 Hs 82226 glycoprotein (tranεmembrane) nmb 302
423067 AA321355 Hs 285401 colony stimulating factor 2 rxeptor, be 301
437457 AA757900 Hs 270823 ESTs, Weakly similar to S65657 alpha-1 C- 296
415000 AW025529 Hs 239812 Homo sapienε εerologically defined breaε 296
437145 AF007216 Hs 5462 εolute earner family 4, εodium bicarbon 296
418838 AW385224 Hs 35198 xtonuclxtide pyrophosphatase/phoεphodi 296
419660 BE280337 Hs 194693 solute camerfamily 7 (cationic ammo 296
409956 AW103364 Hs 727 inhibin, beta A (activin A, xtivm AB a 295
414493 AL133921 Hε 76272 retinoblastoma-binding protein 2 294
416883 AW140128 Hε 184902 ESTs 292
417675 AI808607 Hε 3781 similar to munne leuαne-πch repeat pr 292
418318 U47732 Hε 84072 transmembrane 4 superfamily member 3 292
432841 M93425 Hs 62 protein tyrosine phosphatase, non rxept 292
429640 U83508 Hs 2463 angiopoietin 1 291
449843 R85337 Hs 24030 solute earner family 31 (copper transpo 291
401958 Target Exon 290
416926 H03109 Hs 263395 HT018 protein 290
433691 AA605012 ESTs 288
441892 AB028981 Hs 8021 KIAA1058 protein 287
439453 BE264974 Hs 6566 thyroid hormone rxeptor interxtor 13 287
417165 R80137 Hs 302738 Homo sapienε cDNA FU21425 fiε, clone C 287
414291 AI289619 Hε 13040 G protein-couple, rxeptor 86 287
417696 BE241624 Hε 82401 CD69 antigen (p60, early T-cell xtivati 287
435913 W95006 Hε 269559 ESTs, Weakly similar to S65657 alpha-1 C- 286
422050 AA302741 Hε 25786 ESTε, Moderately similar to JC5238 galac 285
451356 AA748418 Hs 164577 ESTs 285
442085 AA975688 Hs 159955 ESTs 284
427704 AW971063 I Hs 292882 ESTs 283
427247 AW504221 Hs 174103 integπn alpha L (antigen CD11 A (p180) 283
441965 AA972712 Hs 269737 ESTs 282
430268 AK000737 Hs 237480 hypothetical protein FLJ20730 282
450056 BE047394 Hs 8208 ESTs, Weakly similar to S71512 hypotheti 280
407245 X90568 Hs 172004 titin 280
418941 AA452970 Hs 239527 E1 B 55kDa asεxiated protein 5 280
446601 AI312783 Hs 155772 I Homo sapiens thymic stromal co-transport 280
432195 AJ243669 Hs 8127 KIAA0144 gene product 280 449088 AI654048 Hs 196556 ESTs 280
416511 NM.006762 Hs 79356 Lysoεomal associated multispann g membr 280
406648 AA563730 Hs 277477 major histxompatibility complex, class 279
412116 AW402166 Hs 784 Epstein Barr virus induced gene 2 (lymph 278
433793 AW975959 Hs 107513 ESTε, Moderately similar to KIAA1058 pro 278
440255 AI932285 Hs 160569 ESTs 278
410057 R66634 Hs 268107 multimeπn 277
417497 AW402482 Hs 82212 CD53 antigen 277
446733 AA863360 Hs 26040 ESTs, Weakly similar to fatty acid omega 276
431884 AA521246 Hs 210792 ESTs, Weakly similar to ALU8 HUMAN ALU S 275
409969 AW514668 Hs 194258 ESTε, Moderately similar to ALU5_HUMAN A 275
436729 BE621807 transmembrane 4 superfamily member 1 275
431451 AA761378 Hs 192013 ESTs 274
413517 N76712 Hs 44829 ESTs, Weakly similar to I38022 hypotheti 274
447818 W79940 Hs 21906 Homo sapiens clone 24670 mRNA sequence 274
418818 AA228899 Hs 101307 Homo sapienε HUT11 protein mRNA, partial 274
424673 AA345051 Hs 294092 ESTε, Weakly similar to I38022 hypotheti 274
443194 AI954968 matrix Gla protein 271
443804 AL135352 Hs 255883 ESTs, Weakly similar to I38022 hypotheti 271
452870 AW502761 Hs 30909 KIAA0430 gene product 270
430334 AI824719 Hs 143251 ESTs 270
437187 AL080208 Hs 306325 Homo sapiens mRNA, cDNA DKFZp586C1523 (f 270
432279 N95104 Hs 274260 ATP-b ding cassette, sub-family C (CFTR 270
413950 AA249096 Hs 32793 ESTs 270
430016 NM 004736 Hs 227656 xenotropic and polytropic retrovirus rx 270
431710 AI735482 ESTs 270
448749 AW859679 Hs 21902 Homo sapiens clone 25237 mRNA sequence 269
451154 AA015879 Hs 33536 ESTs 269
424541 AW392551 Hs 180559 ESTs, Weakly similar to A56194 thromboxa 269
446899 NM 005397 Hs 16426 podocalyxm like 268
418031 AA648744 Hs 269493 ESTs 268
453902 BE502341 Hs 3402 ESTs 268
405121 mitogen-xtivated protein kinase 8 inter 268
410163 AF151977 Hs 59260 NTT5 protein 267
429632 AW195336 Hs 148910 ESTε 267
437191 NM 006846 Hs 331555 εeπne protease inhibitor, Kazal type, 5 267
455004 AW850303 gb IL3-CT0219-191199030-F09 CT0219 Homo 267
444933 NM.016245 Hs 12150 retinal short-chain dehydrogenaεe/reduct 267
401113 εolute earner family 22 (organic cation 266
419462 AF071076 Hs 112255 nucleopoπn 98kD 266
407635 AW370213 Hs 295232 ESTε, Moderately similar to A46010 X-lm 266
419175 AW270037 KIAA0779 protein 266
408988 AL119844 Hs 49476 Homo εapienε clone TUA8 Cn-du-chat regi 266
452721 AJ269529 Hs 301871 εolute camerfamily 37 (glycerol-3-pho 266
430592 AJ224864 Hs 9688 leukxyte membrane antigen (IRC1) 265
446830 BE179030 Human DNA sequence from clone RP5-1174N9 264
433327 AI674779 Hs 126744 ESTs 264
424868 AI568170 Hs 96886 ESTs 264
429854 R55508 Hs 99472 ESTs 263
427080 AW068287 Hs 301175 ras related C3 botulmum toxin subεtrate 263
456711 AA033699 Hs 83938 ESTε, Moderately similar to MAS2 HUMAN M 263
419777 D60134 Hs 270975 ESTs 263
414577 AI056548 Hε 72116 hypothetical protein FLJ20992 similar to 262
427596 AA449506 Hε 270143 extrxellular glycoprotein EMIUN-2 pr∞ 262
452445 AB002438 Hs 29596 Homo sapiens mRNA from chromosome 5q21-2 262
447482 AB033059 Hs 18705 KIAA1233 protein 262
419110 AA234171 Hs 187626 ESTs 262
450353 AI244661 Hs 103296 ESTs, Weakly similar to S65657 alpha-1 C- 262
419828 T81422 Hs 14922 ESTs 262
427202 BE272922 Hs 173936 interleukin 10 rxeptor, beta 262
412491 W31589 Hs 73957 RAB5A, member RAS oncogene family 261
436496 AA281959 Hs 5210 glia maturation factor, gamma 261
435053 AW629386 ESTs 261
435029 AF167706 Hs 19280 cysteine πch motor neuron 1 261
425976 C75094 Hs 334514 NG22 protein 260
412561 NM_002286 Hs 74011 lymphxyte-xtivation gene 3 260
430539 AK001489 ADP-nbosylation fxtor-like 1 260
419825 AI754011 Hs 7326 ESTs 259
412577 Z22968 Hs 74076 CD163 antigen 258
425894 AW954011 Hs 180711 ESTs 258
410883 D43767 Hs 66742 CCL17 chemokine (TARC) (SCYA17) 258
441028 AI333660 Hs 17558 Homo sapiens cDNA FU14446 fis, clone HE 258
413949 AA316077 Hs 75639 Human TB1 gene mRNA, 3' end 258
434943 AI929819 Hs 92909 chromosome 21 open reading frame 50 258
443605 H06865 Hs 134131 ESTs 257
425017 AL119305 Hs 26409 ESTs 2 57
440334 BE276112 Hs 7165 zinc finger protein 259 256
426075 AW513691 Hs 270149 ESTs Weakly similar to 2109260A B cell 256
425345 AU077297 Hs 155894 protein tyrosine phosphatase, non rxept 256
407174 T79938 Hs 77062 leukxyte immunoglobulin like receptor, 256
443834 AI741510 Hs 173548 ESTs 255
427557 NM.002659 Hs 179657 plasminogen xtivator, urokmase rxepto 255
420539 AA282735 Hs 44004 AD031 protein 255 421177 AW070211 Hs 102415 Homo sapiens mRNA, cDNA DKFZp586N0121 (f 254
437952 D63209 Hs 5944 solute carrier family 11 (proton-coupled 254
422994 AW891802 Hs 296276 ESTε 254
411992 AW816214 Hs 143055 ESTs 254
451180 H61899 Hs 171937 steroid dehydrogenase-like 254
415775 H00747 Hs 29792 ESTs, Weakly similar to I38022 hypotheti 253
429752 H52348 Hs 36636 ESTs 253
414612 BE274552 Hs 76578 protein inhibitor of xtivated STAT3 253
453329 T97205 Hs 193400 ESTs, Weakly similar to 2109260A B cell 2 53
436503 AJ277750 Hs 183924 ubiquitin assxiated and SH3 domain cont 252
445911 AI985987 Hs 145645 ESTs, Moderately similar to ALULHUMAN A 252
433332 AI367347 Hs 44898 Homo sapiens clone TCCCTA00151 mRNA sequ 252
435943 R60194 Hs 31141 Homo sapienε mRNA for KIAA1568 protein, 252
452253 AA928891 Hs 28608 Homo sapiens cDNA FLJ22115 fis, clone H 252
442506 BE566411 Hs 41726 ESTε 252
419972 AL041465 Hs 182982 golgιπ-67 252
431074 BE072772 Hs 8997 ESTε, Moderately similar to A46010 X-lm 252
449129 AI631602 Hs 258949 ESTε 252
440524 R71264 Hs 16798 ESTs 251
419203 AA488719 Hs 190151 ESTs 251
404370 Target Exon 251
432828 AB042326 Hs 287402 chondroitin 4-sulfotransferase 251
439219 N33883 Hs 41322 ESTs 2 51
428044 AA093322 Hs 301404 RNA binding motif protein 3 250
433681 AI004377 Hs 200360 Homo sapiens cDNA FLJ 13027 fis, clone NT 250
437644 AA748575 Hs 136748 Ixtin-like NK cell rxeptor 250
442566 R37337 Hs 12111 ESTs 250
409317 U20165 Hs 53250 bone morphogenetic protein rxeptor, typ 250
450506 NM 00446C I Hs 418 fibroblast xtivation protein, alpha 250
447484 AA464839 Hs 292566 hypothetical protein FLJ14697 250
415165 AW887604 Hs 78065 complement component 7 250
435284 AA879470 Hs 96849 Homo sapienε cDNA FLJ11492 fis, clone HE 250
TABLE 38B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Axession Genbank accession numberε
Pkey CAT Number Accession
412654 1350.1 BG743181 AI830050 BE695688 AA126591 AI903503 R26045 N62894 N63950 AA131619 AI681480 N79626 AA461603 R78979 AW608865 N66622 BF448838 AA779000 AA460314 AI092721 AI870182 AI436284 AI494151 AI127704 AI127702 BE349350 AI093480 AA115264 AA131567 R26840 R78885
433691 2203511 1 AI223854 AI129852 AA605012 436729 6624.1 X75684 AL573167 AI445461 AI453743 AI983655 AI564644 AA977180 AI694111 AI591358 AW071625 AI678712 AI720939 AI927769 BE439796 AI963432 AA292956 AW192593 AI865838 AI696905 AI424384 AI161312 AI911921 AI597801 BI494959 AI240988 AI492554 AW262737 BE044033 AW008570 AW629505 BI494958 AA088439 AA706057 BF222820 BF593608 BE501957 AA524526 BE044134 AW572531 AW015724 BE349186 AA043217 BE219784 AI799814 AA129575 AI671 27 AI470033 BE646195 AW779725 AA903050 AA147228 AA404570 AI075878 W38161 AI972739 AW673152 AA723200 C06123 BF057147 AA627686 AA157944 AI990245 AA662517 T32487 AI800106 AI333170 AI859160 W45410 AI990827 AW275048 AA182640 AA478328 AI298935 AW085158 AW471421 AW103470 AW300456 AW191997 AI823466 AA962397 AA136658 AI251817 AW339104 AA724739 AA411100 AA191349 AA757735 AA037696 AI769516 AW772283 AA010631 AI692846 AI061065 H80983 R79933 AI950693 AI245632 AI349390 AA148284 AI798502 AA487893 AI621320 AW194272 C06365 AA953883 BE858936 AI918523 AI872628 AI927217 AI453453 AI189366 AW338678 AI261359 AI500576 BF477735 AI032569 AI972899 AI985583 Z28771 AI363829 AI693030 AA603586 BE773488 AW339301 BE773489 BE773462 BE773495 AI650338 BE773499 AI745717 BE811475 BE811470 BE811464 BE811418 BE811415 BE811400 BE811398 BE811388 BE811352 BE773501 BE773494 BE773486 BE773474 BE773473 BE773470 BE773461 BE811350 BE811337 BF593847 BG055071 AW675302 BF003068 AA719173 BE811348 AI582462 AI686240 BE773500 AI244845 AI565439 AI918453 A1472527 AI446740 AA035576 AA191414 AW674145 C05782 AI589264 D57558 AI468237 AI432033 AA989662 R21752 BF002457 AA988297 AL574095 AL576200 AL571074 AL574525 AL578810 BG498381 AI928364 BE879732AA479834AA479712 C17732 BM091258 BF843901 AW820230 C17476 BE327120AA129574 AA136645 BF843900AW806193 AA502832 AA649494AL568520AL547960 BE706937 BE811360 BE773498 BE811401 BE773484 BE811437 BE811380 BE811399 BF997171 BF757734 BE926037 AI377596 C06111 AW088968 BE811404 BE811472 A1865912 AI925607 AI871950A1093510 BE905927 BE811435 AA191387 AW772000 BE811453 BE614379 BF844522 BI044896 AI744233 AW984527 C17504 BF843883 AI248307 BE773483 AI567995 W60075 BF941183 AI738844 BE811458 BE773481 AI262930 AA948565 BE706942 BE156360 T65026 AW242958 AW197954 BE905184 AA722206 AI344943 AI348877 AI334860 BE621857 BE156280 AA454099 AA037722 BF843897 AW806183 AA043216 BG482896 AA182734 AA877242AW372926 H27252 R38114 BF851858 BE156214AA190427T91762AA035067 AA837326 T10930 BF906587 BI755027 BG506731 BC008442 BC010166 AL550134 AL553096 AL548700 AL550751 AL547978 AL545286 AL540643 AU118627 AL601379 BI259821 BG741786 BI868522 AU135866 BI552770 BI259210 BI256520 BI255569 BG485098 BI258228 BG498501 BM044512 AU133984 AL556586 BE745111 BI222633 AU133917 BG288151 BI260715 BI550550 BG500773 BI551761 BG707601 BI818593 BF691383 BG721129 BG541578 BE906666 BG751098 BI224135 BG400746 BG478065 BE790436 AW080238 AU137549 BG429896 BE392486 AW961686 BG721056 BE908365 BE546656 BG541235 AW583735 BG528290 BI260895 AW651691 BM048974 BM043805 BG142185 AA315188 AI446615 C06300 BG497644 AA088544 AI815987 BG528631 BE619182 AW239185 AW062910 AW062902 AA347236 F11933 AA488005 AA301631 AA376800 D56120 AA343532AA308636 F00242AA376086 AA316968 AA343799 BI870221 BE910282 BG538748AW960564AV732879 D16854 AA192519 BF922148 AA216013 BG624091 BE544387 BG507008 AW176446 BF790033 BE088925 BE088854 AA921353 R21800 AA011222 T97525
443194 19335.1 BI754027 BF696071 AI351939 BG151298 AI919334 AI401620 BI770165 W72057 T96158 T29478 AA181252 BG927793 AA714431 AA600749 AA181247 AA614756 AA081092 H52207 BG926934 BF222579 BG899001 N64245 AA953040 AI832406 AA102441 BG928081 AA993445 AA916041 AA987847 AA983329 AA737219 AA916443 AW128994 AI492560 AI761847 BC005272 NM 000900 X53331 M58549 BI758966 AL598829 BI754530 BG699770 BE439699 BE440148 AV704365 AV733652 BG212015 BG184149 BG200180 BG212690 BI761222 BG182079 AW338822 AI925631 AI423041 AW071181 AI889836 AW129112 BG925339 AI017633 AA568964 BF725590 AI004210 AI809799 BE083097 BG896220 AW997681 BF668788 BE083134 AW631281 BG193052 BG183095 BE440088 BG185728 AI499579 AA188162 AA864282 BI493352 AA155854 AA836749 AA836844 AA985478 AW082299 AI816747 AA450221 AA971294 BE327509 AI719662 BG576669 AI479382 BF824747 AI741800 BG982962 AI088473 AA916151 AW473324 BG901177 BE439998 AW023269 BE813871 AW999947 BE839108 AV707983 AA369722 AW796627 AW890608 AI341771 AA302459 BI493353 AA366332 AA371104 AA367277 AL547972 BG928011 A1678903 AI699886 AI956165 AA484893 AA643953 AW591063 BG203275 BG211093 AI334791 AA916589 AW058266 A1362370 AI143352 AA508721 AI928079 D57214 BE045265 AA541785 BG219510 BG201686 BG195572 AW019904 AW089242 AA953322 AI686698 F27562 AA614749 D56645 F20774 F30660 F25646 AW023542
AA827300 AA582214 AI701289 AA228293 AI906950 AA230156 AA384572 AW438988 AA742516 BI490938 AA731082 BF665869 BG190518
AV704158 BE439643 AA910666 AA155913 AA923097 AA975721 AA985555 BG927032 AA948389 AA451625 AA916141 AL572719 AV707258
AW083733 AA128053 AI953789 AI911993 AA421798 BG429150 AI915306 Z30130 AA126929 BG926630 AA081013 AA553696 AA916094
BG924321 AI039722 AI954968 AI372839 AI401406 AI538215
431710 16115921 AI422419 AA514370 AI741678 AI735482 AI735081 A1371436 455004 1089114.1 AW850587 AW850589 AW850318 AW850303 419175 35068.1 AB018322 BC012480 BI524873 AW665554 AI934469 AI479916 BF096179 BF096162 BF096132 AA744972 AI951988 AI858339 BE076331
AA886998 AI570585 AI916688 AI678811 AI693109 AI308135 AA669046 AA961064 AI018062 H80618 BE221942 R52609 AI915164 AA365626
Z44671 BI052776 BF882486 BG286184 AI589558 AA931663 AA534979 AI275392 AI273455 R52553 AA829920 H80652 AA360728 F10618
AW953666 AW176773 H85527 AA765570 AA081927 BF093262 BG743753 AL037576 AA534314 BE814964 BE973713 N49493 BE006634
BE006630 AW270037 AA234765 AI334004 BF057179 AI857450 AI341191 AI434143 AI917449 AW517207 AA255424 AW008334 AA847572
AA994211 AA861901 AA581873 AI580157 AI364363 AW242357 AW235291 N55645AA319869 R36911 AA256551 AW044188AI203159 N49403
F02090 AI187299 AI609644 Z40516 AW952314
446830 41421.1 BC020595 BI488430 BG168023 BE179030 AW294203 BF849776 AA459064 AI917452 AW403072 W27419 BF914568 BF798468 AW370558
T35055 AW370623 AA399232 AA214221 AW802987 BF902228 AW370622 BF819597 AW370567 BF914313 AW954040 BF060706 AA194237
T25074 C01285 BI489433
435053 124009.1 AI332638 AA663215 AW629386 430539 31268.1 AK001489 AU129447 BF959274 BG565452 AI245327 AU116848 BF358559 BF358554 BF358570 BG678119 AL515852 AU154607 AI357567
AW874359 Al 122554 AA406478 AI091013 AI866679 AI686163 AA662158 AA911580 D31095 AI302576 BF588761 AU151560 AU143828 AI291610
AW169600 D31161 AA905362 C21179 BE327258 D31474 AW439053 D31309 BF756901 BI838626 BF979839 AU149562 BM142116 AU156455
AA452028 AW473972 AW468490 AA410271 A1475944 BF821859 AA658188 AI360390 AA226320 F37355 F27660 F36093 AA152126 BF930021
BF375775 AW821784AW975085 W16475 D31031 BG696392AW860676AW752864 BI013705 BF965715 BF326604 AW821786
TABLE 38C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence εource The 7 digit numberε in this column are Genbank Identifier (Gl) numbers "Dunham, et al * refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) N__ure 402489 495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
406617 8439858 Plus 36430-36552
401958 3258613 Plus 108411-108629
405121 8102330 Minus 35816-36004,36587-36684
401113 9966541 Minuε 19419-19959
404370 7631003 Plus 127868-128244
TABLE 40A 656 genes upregulated in fibrosis relative to normal body tisεueε
Table 40A liεtε about 656 geneε upregulated in fibrosis relative to normal body tissues that are likely to encode proteins amenable to modulation by small molxules, peptides, or antibodies These genes were εelxted from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expression data for exh probeset obtained from this analysis was expressed as average intensity (Al), a nonrialized value reflxting the relative level of mRNA expression The protein products of these geneε often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death-domain, 7tm, phosphatase, or lon.transporter) Certain predicted protein domainε are noted
Pkey Unique Eoε probeεet idenufier number
ExAccn Exemplar accession number, GenBank xcesεion number
UniGenelD UniGene number
Pred Prot Domainε Certain predicted protein domaiπε Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280) UniGene Title UniGene gene title
R1 95th percentile of fibrosis Als divided by the 50th percentile of normal tisεue Alε, where the 10th percentile of all normal tissue Als was subtrxted from both the numerator and denominator
Pkey, ExAccn, UnigenelD, Unigene Title, Pred Prot Domains, R1
442275, AW449467, Hs 54795, Homo sapienε εxretoglobm, family 3A, m, Uteroglobιn,TM=M,SS=Y, 3947
428434, AW363590, Hε 65551 , Homo sapiens, Similar to DNA segment, Ch, LBP_BPI_CETP_C,TM=M,SS=Y, 3235 439335, AA742697, Hs 62492, NMJ52863 Homo sapiens sxretoglobin, fa, none,, 2849
406964, M21305, , FGENES predicted novel εecreted protein, none.none, 2790
425211, M18667, Hε 1867, progastπcsm (pepsmogen C), asp,TM=M,SS=M, 2790
441835, AB036432, Hs 184, advanced glycosylation end product-spxi, hom∞box,Acyltraπsferase,πotch,EGF,aπk,Acyltransferase, 2723
446921, AB012113, Hs 16530, εmall inducible cytokine εubfamily A (Cy, IL8„ 2497 428330, L22524, Hs 2256, matrix metalloproteinase 7 (matπlysin, , Peptidase M10„ 2438
431723, AW058350, Hs 278966, Homo sapiens mRNA, cDNA DKFZp564B2062 (f, PMP22_Claudιn,none, 2335
409153, W03754, Hs 50813, hypothetical protein FLJ20022, fibπnogen_C„ 2329
431089, BE041395, Hs 374629, ESTs, Weakly similar to unknown protein , none.none, 18 23
425371, D49441, Hs 155981, mesothelin, none,TM=M,SS=M, 18 17 448133, AA723157, Hs 73769, folate rxeptor 1 (adult), Folate_rx,MIP,TM=M,SS=M, 1764
421502, AF111856, Hs 105039, solute earner family 34 (sodium phospha, Rιbosomal_L20,Na_Pι_cotraπs,TM=Y,SS=N, 1733
421798, N74880, Hs 355462, N-acylsphiπgosine amidohydrolase (acid c, SAPA.SurfxtanLB.πone, 1681
419556, U29615, Hs 91093, chitmase 1 (chitotπosidase), Glyco_hydro_18,CBM_14,TM=M,SS=Y, 1624
419092, J05581 , Hε 89603, mucin 1 , transmembrane, SEA,TM=Y,SS=M, 1606 426174, AA547959, Hs 115838, Homo sapiens similarto Echinoidin (LOC1, none.none, 1584
406672, M26041, Hs 198253, major histocompatibility complex, class , ιg,MHC_ll_alpha,TM=M SS=M, 1542
421110, AJ250717, Hs 1355, cathepsin E, asp,, 1508
444342, NM.014398, Hs 10887, similarto lysosome assxiated membrane , Lamp,TM=Y,SS=M, 1494 406621, X57809, Hs 181125, immunoglobulin lambda locus, ιg,HSP70,Ppx GppA,TM=M,SS=N, 1436
443709, AI082692, Hs 134662, ESTs, SNF,fn3,none, 1405
428970, BE276891, Hs 194691, retinoic acid induced 3 (RAIG1), metabo, 7tm_3,TM=Y,SS=M 1388
457200, U33749, Hs 197764, thyroid transcnption factor 1 , homeobox,TM=M,SS=N, 13 86 432519, AI221311, Hε 130704, ESTε, Weakly similar to BCHUIA S-100 pro, none.none, 1382
422355, AW403724, Hs 300697, coagulation factor VII (serum prothrombi none.ig, 1362
430280, AA361258 Hs 237868, interleukin 7 receptor; fn3,none, 1347
415457, AW081710, Hs 7369, Homo εapieπs testes εpxific A2 homolog , MORN,εugar_tr,TM=Y,SS=M 1335
431164, AA493650 Hε 94367, thyroid transcnption factor 1, none.hom∞box, 13 32 414998, NM.002543, Hs 77729, oxidised low density lipoprotein (lectin, lxlm_c,TM=Y,SS=M, 1283
400269, , Hs 253495, Eos Control, lxtιn_c,Collagen,Xlιnk„ 1230
424310, AA338648, Hs 50334, testeε development related NYD-SP22, none,TM=M,SS=N, 11 81
451558, NM_001089, Hs 26630, ATP-bmding cassette, sub-family A (ABC1, ABC_tran,SRP54,TM=Y,SS=M 11 79
452304, AA025386, Hs 61311, ESTs, Weakly sιmιlarto S10590 cysteιne , none,none, 11 68 445537, AJ245671, Hs 12844, EGF-like domain, multiple 6, EGF.MAM,, 11 56
423778, Y09267, Hs 132821, flavin containing on∞xygenase 2, FMO lιke,pyr_redox,TM=Y,SS=M, 11 41
414812, X72755, Hs 77367, monokine induced by gamma interferon, IL8,TM=M,SS=Y, 11 31
430832, AI073913, Hs 100686, ESTε, Weakly similar to JE0350 Anterior , none.none, 11 25
407910, AA650274, Hs 41296, fibronxtin leucine πch transmembrane p, fπ3,LRR,LRRCT,LRRNT,TM=Y,SS=M, 11 15 451497, H83294, Hs 284122, Wnt inhibitory factor-1, EGF.WIF,, 11 07
430250, NM_016929 Hs 283021, chloride intracellular channel 5, none,TM=M,SS=N, 11 07
411020, NM_006770, Hs 67726, macrophage rxeptor with collagenous εtr, SRCR,Collageπ,TM=Y,SS=M, 11 05
446619, AU076643, Hs 313, sxreted phosphoprotein 1 (osteopontin, , Osteopontm,, 11 01
438091, AW373062, Hε 351546, nuclear rxeptor subfamily 1, group I, m, hormone_rx,zf-C4,none, 1097 413048, M93221, Hs 75182, mannoεe receptor, C type 1, fn2,lxtιn_c,Rιcm B lectιn,Xlιnk,TM=Y,SS=M, 1093
432231, AA339977, Hs 274127, CLST 11240 protein, none,TM=M,SS=M, 10 81
416402, NM.000715, Hs 1012, complement component 4-bιndιπg protein, , suεhι,TM=M,SS=M, 1077
418156, W17056, Hε 83623, nuclear rxeptor subfamily 1, group I, m, hormone_rec,zf-C4,none, 1063
436553, AW407157, Hs 181125, immunoglobulin lambda Ixus, ιg,HSP70,Ppx-GppA,TM=M,SS=N, 1058 421071, AI311238, Hs 104476, ESTs, Weakly εimilarto CGHUIE collageπ , none,TM=Y,SS=M, 1057
418007, M13509, Hs 83169, matrix metalloprote ase 1 (interstitial hemopexιn,Peptιdase_M10,Astxιn,PG_bιndιng_1„ 1033
419086, NM.000216, Hs 89591, Kallmann syndrome 1 sequence, fn3,wap„ 1030
407786, AA687538, Hs 38972, tetraspan 1, transmembrane4,TM=Y,SS=M, 10 28
441384, AA447849, Hs 288660, retinoic acid induced 3, 7tm_3,none, 1026 453914, NM_000507, Hs 574, fructose-1 ,6-bιεphosphatase 1 , FBPase TM=M,SS=N, 1022
435523 T62849, Hs 11090, membrane-spanning 4-domaιns, εubfamily A, πone,TM=Y,SS=M, 1009 423354, AB011130, Hε 127436, calcium channel, voltage dependent, alph, vwa,Cxhe,TM=M,SS=N, 1003 415323, BE269352, Hs 949, neutrophil cytosolic factor 2 (65kD, chr, SH3,TPR,TM=M,SS=N, 1002 408562, AI436323, Hs 31141, roundabout (axon guidance receptor, Dros, ιg,fn3,TM=M,SS=N, 1002 448782, AL050295, Hs 362806, KIAA0758 protein, 7tm_2 ιg,GPS,SEA,TM=Y,SS=N, 986
419235, AW470411, Hs 288433, neurotπmm, none.none, 979 415992, C05837, Hs 145807, hypothetical protein FLJ13593, none,TM=Y,SS=M, 974 418883, BE387036, Hs 1211, xid phosphatase 5, tartrate resistant, Metallophos,TM=M,SS=M 970 439018, AW300887, Hε 26638, membrane-εpannmg 4-domaιnε, εubfamily A, none,TM=Y,SS=M, 969 442652, AI005163, Hs 201378, Homo sapiens cDNA FLJ40427 fis, none,TM=M,SS=N, 9 68
446291, BE397753 Hε 14623, interferon, gamma-inducible protein 30, GILT,TM=M,SS=Y, 964 408380, AF123050, Hε 44532, diubiquitin, ubιquιtm,TM=M,SS=N, 954
438089, W05391, Hs 351546, nuclear receptor subfamily 1, group I, m, hormone_rx,zf-C4,none 952 449494, AW237014, Hs 315369, aquapoπn 4, MlP.none, 951 456062, AI866286, Hε 71962, ESTε, Weakly similar to 836298 proline r, none.none, 942
446428, AW082270, Hε 12496, ESTε, Weakly similar to ALU4 HUMAN ALU S, none.none, 941 421952, AA300900, Hs 98849, dynein lightchain 2B (DNLC2B)', none.none, 9 19
407949, W21874, Hs 247057, ESTs, Weakly similar to 2109260A B cell , Rιbosomal_S14,ank,pkιπase,death,noπe, 9 16 456034, AW450979, , gb UI-H-BI3-ala-a-12-0-UI s1 NCI_CGAP.Su, none.none, 9 15 407788, BE514982, Hs 38991, S100 calcium-bmdmg protein A2, efhand,S_100,S_100,efhand, 915
416965, N26223, Hs 160436, MDAC1, none,NA,NA, 903 443324, R44013, Hs 164225, ESTs, none.none, 903
435575, AF213457, Hs 44234, tπggeπng rxeptor expressed on myeloid, ιg,TM=Y,SS=M, 900 440273, AI805392, Hs 325335, Homo sapienε cDNA FU23523 fis, clone L, none.none, 899 424527, AW138558, Hs 334873, ESTs, Weakly similar to I54374 gene NF2 , Zn carbOpepfnone, 880
409203, AA780473, Hs 687, cytxhrome P450, subfamily IVB, polypept, p450,TM=M,SS=Y, 876 423387, AJ012074, Hs 348500, vasoxtive intestinal peptide rxeptor 1, 7tm_2,HRM,CSD,TM=Y,SS=M, 874 443907, AU076484, Hs 9963, TYRO protein tyrosine kinase binding pro, πone,TM=M,SS=Y, 873 425367, BE271188, Hs 155975, protein tyrosine phoεphatase, rxeptor t none,TM=M,SS=Y, 8 68 418918, X07871, Hs 89476, CD2 antigen (p50), sheep red blood cell , ιg,TM=Y,SS=M, 856
421563, NM.006433, Hs 105806, granulysin, none,, 8 55
450726, AW204600, Hs 355462, HUMPSPBA Human pulmonary surfxtant-asso, SAPA,SurfactanLB,none, 851 419693, AA133749, Hs 301350, FXYD domain containing ion transport reg, ATP1G1_PLM_MAT8,TM=Y,SS=M, 851 424450, AL137526, Hs 374425, dynein intermediate chain 2, WD40„ 842 402474, , , NMJ04079 Homo sapienε cathepsin S (CTSS, Peptιdase_C1„ 841
458079, AI796870, Hs 54277, Homo sapiens similar to RIKEN cDNA 28100, none,TM=M,SS=N, 840 424779, AL046851, Hs 153053, CD37 antigen, transmembraπe4,TM=Y,SS=M, 836 453310, X70697, Hε 553, εolute earner family 6 (neurotransmitte, SNF,5HT_transporter,TM=Y,SS=N, 834 448140, AF146761, Hε 20450, BCM like membrane protein precursor, ιg,TM=Y,SS=N, 833 404240, , , NM.018950 Homo sapienε major hiεtxompat, ιg,MHC_l,TM=Y,SS=M, 828
459702, AI204995, gb an03c03 x1 Stratagene schizo brain S1, none.none, 8 17 449523, NM 000579, Hs 54443, chemokine (C-C motif) rxeptor 5, 7tm_1,TM=Y,SS=M, 8 17 442994, AI026718, Hs 16954, ESTs, aπk,pkιnase,death,Rιbosomal S14, 8 12 446998, N99013, Hs 278966, Homo sapienε mRNA, cDNA DKFZp564B2062 (f, PMP22_Claudιn,none, 807 420137, AA306478, Hs 95327, CD3D antigen, delta polypeptide (TιT3 co, ITAM,TM=Y,SS=M, 801
435472, AW972330, Hs 283022, tπggeπng rxeptor expresεed on myeloid, ιg,TM=M,SS=M, 7 99 432441, AW292425, Hε 163484, intron of hepatxyte nuclear factor-3 al, Forkjiead.noπe, 799 409208, Y00093 Hs 172631, integπn, alpha X (antigen CD11C (p150)„ vwa,FG-GAP,ιntegnn_Avwa,mtegπn_A FG-GAP, 794 432606, NM.002104, Hs 3066, granzyme K (seπne protease, granzyme 3„ trypsιn,TM=Y,SS=M, 792 442832, AW206560, Hs 253569, ESTs, none.none, 790
412104, AW205197, Hs 240951, Homo sapiens, Similarto RIKEN cDNA 2210, πone,TM=M,SS=N, 789 427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lilb, r; ιg,TM=Y,SS=M, 786 443951, F13272, Hs 356835, ferπtin, light polypeptide, PMP22_Claudιπ,πoπe, 784
418299, AA279530, Hs 83968, integnn, beta 2 (antigen CD18 (p95), ly, ιntegπn_B,EGF,PSI,TM=Y,SS=M, 779 447131, NM.004585, Hs 17466, retinoic acid receptor responder (tazaro, none M=Y,SS=N, 778 423961, D13666, Hs 136348, penostin (OSF-2os), Fascιclιn,TM=M,SS=M, 773 424917, AI636208 Hs 96901, hypothetical protein FLJ23049, noπe,TM=M,SS=N, 772 438564, AA381553, Hs 198253, major histocompalibility complex, clasε , ig.MHC.II.alpha none, 765
456672, AK002016 Hε 114727, Homo sapiens, clone MGC 16327, mRNA, com, none,PK,PK_C,myosιn_head,RhoGAP, 764 427792, M63928 Hs 180841, tumor necroεiε factor rxeptor superfami, SRP14,TNFR_c6„ 763 436954, AA740151, Hs 130425, ESTs, none.none, 758 429732, U20158, Hs 2488, lymphxyte cytosolic protein 2 (SH2 doma, SH2„ 756 407601 , AC002300, Hs 37129, sodium channel, nonvoltage-gated 1 , beta, ASC,TM=Y,SS=M, 755
417105, X60992, Hs 81226, CD6 antigen, SRCR TM=Y,SS=M, 7 51 414821, M63835, Hs 77424, Fc fragment of IgG, high affinity la, re, ιg,TM=Y,SS=M, 746 444381, BE387335, Hs 283713, hypothetical protein BC014245, Collagen,TM=M,SS=M, 740 432222, AI204995, , gb an03c03 x1 Stratagene schizo brain S1 , none.none, 738 422667, H25642, Hs 132821, ESTε, FMO lιke,FM04ιke, 737
444527, NMJ05408, Hs 11383, small inducible cytokine subfamily A (Cy, IL8„ 736 457411, AW085961, Hs 130093, iroquois-claεε hom∞box protein IRX2, none none, 732
439237, AW408158, Hs 318893, ESTs, Weakly similar to A47582 B-cell gr, Fuππ-lιke,pkιπase,Rxep_L_domaιn,YLP,none, 732 419231, AL046294, Hs 136245, ESTs, Weakly similarto T17227 hypotheti, none.none, 730 438873, AI302471, Hs 124292, Homo sapiens cDNA FLJ23123 fis, clone L, none.none, 727
424027, AW337575, Hs 201591, ESTs, 7tm_2,HRM,none, 726 428927, AA441837, Hs 90250, Homo sapiens hypothetical protein FLJ231, none.none, 724 432435, BE218886, Hs 282070, ESTs, none none, 7 22
428467, AK002121, Hs 184465, hypothetical protein FLJ11259, noπe,TM=Y,SS=M, 721 416030, H15261, Hs 21948, ESTs, none.none, 720
433293, AF007835, Hs 32417, hypothetical protein MGC2742, none TM=M,SS=N, 7 18
418741, H83265, Hs 8881, ESTs, Weakly similar to S41044 chromoεom, pkιnase,Actιvιn rxp,pkιnase,Actιvιn_rxp, 7 16 420656, AA279098, Hs 187636, ESTs, none.none, 7 14 427698, AW972594, Hs 335499, ESTs, none.none, 7 11 432268, BE311856, Hs 274230, 3-phosphoadeπosιne 5'-phosphosu!fate εy, APS_kιnase ATP-sulfurylase,TM=M,SS=N, 706
413859, AW992356, Hε 8364, Homo εapienε pyruvate dehydrogenase kma, SAM_PNT,none, 704 430413, AW842182 Hs 241392, small inducible cytokine A5 (RANTES), IL8,TM=M,SS=Y, 704 452363, AI582743, Hs 94953, Homo sapienε, Similar to complement comp, C1q,Collagen„ 703 421481, AW391972, Hs 104696, KIAA1324 protein, none,TM=M,SS=M, 701 418945, BE246762, Hs 89499, arxhidonate 5-lιpoxygenase, lιpoxygenase,PLAT,TM=M,SS=N, 697
452281, T93500, Hε 28792, Homo εapienε cDNA FLJ11041 fis, clone PL, TGFb propeptide.TGF-beta.none, 696 458124, AW005548, Hs 124590, ESTs, none.none, 694
422846, BE513934, Hs 1583, neutrophil cytosolic fxtor 1 (47kD, chr, SH3,PX,TM=M,SS=N, 693 411027, AF072099, Hs 67846, leukxyte immunoglobulin-like rxeptor, , ιnosιtot_P,ιg,TM-M,SS=N, 692 428820, AA436187, Hε 172631, integπn, alpha M (complement component , vwa,ιntegπn_A,FG-GAP,TM=Y,SS=M, 690
423575, C18863, Hε 163443, intron of penostin (OSF-2os), Faεciclin.none, 689
419490, NM_006144, Hε 90708, granzyme A (granzyme 1, cytotoxic T-lymp, trypειn,TM=M,SS=M, 689 450954, AI904740, Hs 25691 , rxeptor (calcitonin) xtivity modifying, none,TM=Y,SS=M, 687 425976, C75094, Hs 334514, NG22 protein, voltage CLC,TM=Y,SS=M, 684 425555, AA359291, Hs 130767, Homo εapienε cDNA FLJ23553fis, clone L, LRR,TM=M,SS=N, 681
414991, C17898, , Homo sapiens up-regulated by BCG-CWS (LO, Zip.none, 680 410342, R31350, Hs 743, Fc fragment of IgE, high affinity I, rx, ITAM,TM=Y,SS=M, 680 422163, AF027208, Hs 112360, prominm (mouεe) like 1, noπe,TM=Y,SS=M, 679 445885, AI734009, Hs 127699, KIAA1603 protein, none.none, 677 436576, AI458213, Hs 77542, ESTs, 7tm_1,DnaJ, 677
417079, U65590, Hs 81134, interleukin 1 rxeptor antagonist, IL1„ 676 424711, NM.005795, Hs 152175, calcitonin rxeptor-like, 7tm 2,HRM,TM=Y,SS=M, 675 416847, L43821, Hs 80261, enhancer of .lamentation 1 (cas-like do, SH3,TM=M,SS=N, 673 426251, M24283, Hs 168383, intercellular adhesion molxule 1 (CD54), ιg,ICAM_N,TM=M,SS=M, 671 417929, R27219, Hs 74647, Human T-cell rxeptor xtive alpha-chain, ig.abhydrolase, 670
412584, X54870, Hε 74085, DNA εegment on chromosome 12 (unique) 24, none,lxtιn_c, 670 428227, AA321649, Hs 2248, small inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 668 421445, AA913059, Hs 104433, Homo sapiens, clone IMAGE 4054868, mRNA, ιon_trans,K_tetra,asp, 665 439750, AL359053, Hs 57664, Homo sapienε mRNA fall length insert cDN, IMPDH_C,IMPDH_N,CBS,ιntegπn_B,Rιcιn B Ixtin, 662 428582, BE336699, Hs 185055, BENE protein, πoπe,TM=Y,SS=M, 660
453142, AA033648, Hs 7473, Homo sapienε gap junction protein, alpha, coπnexm,TM=Y,SS=M, 6 60 432374, W68815, Hε 301885, Homo εapiens cDNA FU11346 fis, clone PL, none.none, 656
448569, BE382657, Hs 21486, signal transducer and xtivator of trans, SH2,STAT,STAT_bmd,STAT_prot,TM=M,SS=N, 6 54 424321, W74048, Hs 1765, lymphxyte-spxific protein tyrosine km, SH2,SH3,pkmase,TM=M,SS=N, 651 446932, AA961459, Hs 125644, ESTs, none.LRR.LRRNT, 650
427247, AW504221, Hs 174103, integnn, alpha L (antigen CD11A (p180)„ vwa,ιntegnn_A,FG-GAP,TM=Y,SS=M, 648 425998, AU076629 Hs 165950, fibroblast growth fxtor rxeptor 4, ιg,pkmase,TM=M,SS=M, 647 447232, AW499834, Hε 327, interieukin 10 rxeptor, alpha, none,TM=M,SS=M, 646 431745, AW972448, Hε 163425, Novel FGENESH predicted cadhenn repeat , none.none, 643 417370, T28651, Hε 374466, tryptophanyl-tRNA synthetase, WHEP-TRS,tRNA-synL1b„ 641
422241, Y00062, Hε 170121, protein tyroεine phoεphatase, rxeptor t, kιπesιn,fπ3,Y phoεphatase,TM=M,SS=N, 640 429610, AB024937, Hs 211092, LUNX protein, PLUNC (palate lung and nas, none,, 639 409340, BE174629, Hs 321130, hypothetical protein MGC2771, aa_permeases,pyrιdoxaI_deC,bromodomaιn,PHD,MBD,AT_hook,DDT,PI3_PI4_kιnase,FAT,FATC,BolA,RUN,TM=M,SS=N, 637 413385, M34455, Hs 840, indoleamme-pyrrole 2,3 dioxygenase, IDO,TM=M,SS=N, 636
451820, AW058357, Hs 199248, ESTs, 7tm_1,TM=Y,SS=M, 634
408369, R38438, Hs 118747, SLC15A2 Solute camerfamily 15 (H+/pep, PTR2,TM=Y,SS=N, 6 32 424247, X14008 Hs 234734, lysozyme (renal amyloidosiε), lys.ig.FAD.Synth.ldh Idh.C.pkinase , 632 444090 S69115, Hs 10306, natural killer cell group 7 sequence, PMP22_Claudιn,TM=Y,SS=M, 631 416819, U77735, Hs 80205, pιm-2 oncogene, pkinase,, 630 421659, NM.014459, Hs 106511, protocadhenn 17, cadheπn,TM=M,SS=M 627 415198 AW009480 Hs 943, natural killer cell transcript 4, none,TM=M,SS=N, 626 424273 W40460, Hs 144442 phoεpholipaεe A2, group X, phoslιp,TM=M,SS=Y, 6 24
429083 Y09397, Hs 227817, BCL2-related protein A1, Bcl-2,TM=M,SS=N, 623 452194 AI694413, Hs 373599, olfactory rxeptor, family 2, subfamily , none.none, 622 424144 AA454033, Hs 41644, AKAP-assxiated sperm protein, Rlla , 6 21
414142, AW368397, Hs 334485, hemicentin (fibulin 6), EGF,ιg,tsp_1,hormone4,squaεh,TIL,Adeπo_E3_CR1,TM=M,SS=M, 621 442006, AW975183, Hs 372210, ESTs, Weakly similarto S72482 hypotheti, none.none, 6 20
420256, U84722, Hs 76206, cadhenn 5, type 2, VE-cadhenn (vascula, cadheπn,Cadhenn_C_term,TM=Y,SS=M, 6 19 421379, Y15221, Hs 103982, small inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 6 17 440452, AI925136, Hs 55150, ESTs, Weakly similarto CAYP_HUMAN CALCY, none.NA.NA, 6 17 421462, AF016495, Hs 104624, aquapoπn 9, MIP,TM=Y,SS=M, 6 16 452960, AK001335, Hs 31137, protein tyrosine phosphatase, receptor t Y_phosphataεe,noπe, 6 15
410361, BE391804, Hε 62661, guanylate binding protein 1, interferon-, GBP,GBP_C,TM=Y,SS=M, 6 13 415765, NM 005424, Hε 78824, tyrosine kinase with immunoglobulin and , EGF,fn3,ιg,pkmase lammιn_EGF,TM=M,SS=Y, 612 430478, NM 014349, Hs 241535, apolipopratem L, 3, MotA_ExbB,TM=Y,SS=M, 6 12 413869 NM 000878, Hs 75596, interleukin 2 receptor, beta, πone,TM=Y,SS=M, 609 446608 N75217, Hs 175622 ESTs, Armadιllo_seg,HEAT_PBS,TM=M,SS=M, 608
430378, Z29572, Hs 2556, tumor necrosis fxtor receptor superfami, IL2„ 608 426116 AA868729, Hs 144694, ESTs, none.none, 606 445033 AV652402, Hs 72901, cyclm-dependent kinaεe inhibitor 2B (p1, ank,, 6 05 426721, AA383588, Hε 288545, ESTε Weakly similar to T29012 hypotheti, zf-C2H2,TM=M,SS=N, 605 429228, AI553633, Hs 356828, ESTs, none.none, 605
421757, Z20897, Hs 296259, paraoxonase 3, Arylesterase,, 604
437669, AI358105, Hs 123164, ESTε, Weakly similar to match to ESTs AA, none,pkιnase,pkιnase_C, 603 419508, AW997938, Hs 90786, ATP-binding cassette, sub-family C (CFTR, ABC_tran,ABC_membrane,TM=Y,SS=M, 602 428667, AI375550, Hs 346868, nucleolar protein p40, homolog of yeast , none.none, 601 432731, R31178, Hs 287820, fibronectin 1, fn1,fπ2,fn3,none, 595
446566, H95741, Hs 17914, membrane-spanning 4-domaιπs, subfamily A, none,TM=Y,SS=M, 595 450656, AA010539, Hs 18912, unnamed protein product, zf-C2H2„ 594 418460, M26315, Hs 85258, CD8 antigen, alpha polypeptide (p32), ιg,TM=Y,SS=M, 594 424054, AA334511 , Hs 26638, membrane-spanning 4-domaιns, εubfamily A, noπe,TM=Y,SS=M, 594 408048, NM.007203, Hε 42322, A kinase (PRKA) anchor protein 2, Paralemmιn,TM=M,SS=N, 594
438670, AI275803, Hs 123428, ESTs, πone,NA,NA, 591 424238 AA337401, Hs 137635, ESTs, none,TM=M,SS=M, 590 444143, AW747996, Hs 160999, ESTs Moderately similar to A56194 throm, Bcl-2,none, 589 423690, AA329648, Hs 23804, ESTs, Weakly similar to PN0099 son3 prot, ιon_trans,IQ none, 588 409799, D11928, Hs 76845 phosphoseπne phosphatase-like, Hydrolase,TM=M,SS=N, 581
407239, AA076350, Hs 67846, leukxyte immunoglobuliπ-like rxeptor, , ιg,TM=Y,SS=M, 581 411125, AA151647, Hs 68877, cytxhrome b-245, alpha polypeptide, none,TM=Y,SS=M, 580 420340, NM 000734, Hs 97087, CD3Z antigen, zeta polypeptide (TιT3 com, ITAM,TM=M,SS=M, 579 431681, AK000378, Hs 267566, hypothetical protein FLJ20371, sugar_tr,TM=Y,SS=N, 579 413441 , AI929374, Hs 75367, Src-like-adapter, SH2,SH3,TM=M,SS=N, 579
443257, A1334040, Hs 11614, HSPC065 protein, trypsιn,TM=M,SS=N, 576 415801, R24219, Hε 278443, Fc fragment of IgG, low affinity lib, re, ιg,TM=Y,SS=N, 570 435299, AI745458, Hs 343026, ESTε, Weakly similar to T20593 hypotheti, noπe.NA.NA, 569 415995, NM.004573, Hs 355888, phospholipase C, beta 2, C2.PI PLC-Y.PI PLC-X,TM=M SS=N, 567 436772, AW975688, Hs 348918, metallothionein 1E (functional), 7tm_2,HRM,noπe, 567
431385, BE178536, Hs 11090, membrane-spanning 4-domaιns, subfamily A, none.none, 566 419833, AA251131 , Hs 220697, Homo sapiens tryptophanyl-tRNA synthetas, WHEP-TRS,tRNA-synt_1b,πone, 566 421859, AA356620, Hs 108947, KIAA0050 gene product, ank,PH,ArfGap„ 564 407756, AA116021, Hε 38260, ubiquitin spxific protease 18, UCH-1.UCH-2,, 563 425354, U62027, Hs 155935, complement component 3a rxeptor 1 , 7tm_1 ,TM=Y,SS=M, 563
423533, NM_014339, Hs 129751, interleukin 17 receptoπ none,TM=Y,SS=M, 563 419577, L36531, Hs 91296, integnn, alpha 8, integπn A,FG-GAP,TM=Y,SS=N, 561 452561, AI692181, Hε 49169, KIAA1634 protein, TPR,PDZ,WW,Guany!ate_kιn,TM=M,SS=N, 561 428677, AI657119, Hε 351582, troponin I, cardiac, none,TM=M,SS=N, 560 425509, AF079363, Hs 158213, sperm asεxiated antigen 6, Armadιllo_εeg,HEAT_PBS,TM=M,SS=N, 558 453852, AW961818, Hε 211592, MUM2 protein, pkιπaεe,DAG_PE-bιnd,C2,pkιnase_C,none, 557 421924, BE514514, Hs 109606, coronin, xtm-binding protein, 1A, WD40,ldh_C,TM=M,SS=N, 557 448030, N30714, Hε 325960, membrane-εpanning 4-domaιnε, εubfamily A, none,TM=Y,SS=M, 555 431630, NM.002204, Hε 265829, integπn, alpha 3 (antigen CD49C, alpha , FG-GAP,Rhabd _glycop,ιntegπn_A,TM=Y,SS=M, 553 410257, BE244044, Hs 61469, hypothetical protein, none.none, 553
441965, AA972712, Hs 269737, ESTs, pkιnase,Actιvιn_recp,TSPN,Collagen, 552 413934, U03056, Hs 75619, hyaluroπoglucosamtntdase 1, mtegπn_B,Glyco hydro_56„ 552
424517, AI539443, Hs 137447, Homo sapiens cDNA FLJ12169 fis, clone MA, SH2,STAT,STAT_bιnd,STAT_prot,none, 550 447357, AI375922, Hs 132821 , ESTs, FMO-lιke,FMO-lιke, 546 422109, S73265, Hs 1473, gastππ releasing peptide, Bombesιn,Defensιn_propep,TM=M,SS=M, 546
447033, AI357412, Hs 157601, Predicted gene Eos cloned, sxreted w/V, none.none, 545 417412, X16896, Hs 82112, interleukin 1 rxeptor, type I, ιg,TIR,TM=M,SS=M, 545 436057, AJ004832, Hs 5038, neuropathy target esteraεe, cNMP bιndιng,ιonjrans,Patatιn,TM=Y,SS=M, 541 417497, AW402482, Hs 82212, CD53 antigen, transmembrane4,TM=Y,SS=M, 541 439285, AL133916, Hs 47860, hypothetical protein FLJ20093, ig pkιnase,LRR,LRRNT,LRRCT,πone, 540
452698, NM.001295, Hs 301921, chemokine (CC motif) rxeptor 1, 7tm_1,TM=Y,SS=M, 540 443623 AA345519, Hs 9641, complement component 1, q subcomponent, , C1q,Collagen„ 540 446272 BE268912, Hs 14601, hematopoietic cell-specific Lyn substrat SH3,HS1_rep,TM-M,SS=N, 538 437275, AW976035, Hs 292396, ESTs, Weakly similar to A47582 B-cell gr, πone.Fπzzled.Fz, 537 419660, BE280337, Hε 194693, εolute earner family 7 (cationic ammo , aa_permeases,TM=Y,SS=M, 537
449853, AF006823, Hs 24040, potassium channel, subfamily K, member 3, ιoπ_trans,TM=Y,SS=M, 536 442434, AA995787, Hs 129583, ESTs, IRK.none, 536 428065, AI634046, Hs 157313, ESTs, ICE_p20,DED,ICE_p10,ICE_p20,DED, 536 445333, BE537641, Hs 44278, hypothetical protein FLJ12538 similar to, ras,arf,TK„ 533 425638, NM.012337, Hs 158450, nasopharyngeal epithelium εpxific prote, πone,TM=M,SS=N, 532 419034, NM_002110, Hε 89555, hemopoietic cell kinaεe, SH2,SH3,pkιπase,TM=M,SS=N, 532 452416, AA026115, Hε 114777, ESTε πone,Pθφhobιl_deam, 529 425205, NM.005854, Hε 155106, rxeptor (calcitonin) activity modifying, noπe,TM=Y,SS=N, 529
440475, AI807671 , Hs 24040, potassium channel, subfamily K member 3, ion traπs.πone, 528
417355, D13168, Hs 82002, endothelin receptor type B, 7tm_1 zf-C3HC4,fn3,SPRY,KRAB,zf-C2H2,rve,zf-B_box,TM=Y,SS=M, 5 28 436120, AI248193, Hs 119860, ESTs hemej.noπe, 527
418307, U70867, Hs 83974, solute carrier family 21 (prostagland , OATP N,OATP_C,TM=Y,SS=M, 527 409745, AA077391, , gb 7B14E12 Chromosome 7 Fetal Brain cDNA, 7tm_1,zf-C3HC4,fπ3,SPRY,KRAB,zf-C2H2,rve,zf B_box,TM=Y,SS=M, 526 421554, AW137676, Hs 97775, ESTs, none.none, 523
408308, AL033377, Hs 44197, hypothetical protein DKFZp564D0462, none.none, 522 410434, AF051152, Hs 63668, toll like rxeptor 2, LRR,LRRCT,TIR,TM=M,SS=M, 521 421585, U95626, Hs 302043, chemokine (C-C motif) receptor-like 2 (, 7tm 1,TM=Y,SS=M 5 19 400261 , , Hs 1802, Eos Control, ig.MHC ll_beta,TM=Y,SS=M, 5 19
436856, AI469355, Hs 127310 ESTs, pkinase,rrm,TM=M,SS=N, 5 18 408761, AA057264, Hs 238936, ESTs, Weakly similarto (deflme not ava, 7tm 1,none, 5 17 425023, AW956889, Hs 154210, EDG-1 (endothelial differentiation sph, 7tm_1,TM=Y,SS=M, 5 16
452203, X57522, Hs 352018, transporter 1, ATP binding cassette, sub, ABC_tran,ABC_membrane,SRP54,Thymιdylate_kιn,TM=Y,SS=M, 5 16 451220, AF124251, Hε 26054, novel SH2-contaιnιng protein 3, SH2,TM=M,SS=N, 5 15 417771, AA804698, Hs 82547, retinoic acid rxeptor responder (tazaro, none.none, 5 14 424925, NM.002432, Hs 153837, myeloid cell nuclear differentiation ant, PAAD DAPIN.HIN,, 5 14 451099, R52795, Hs 25954, interleukin 13 receptor, alpha 2, fn3,TM=Y,SS=M, 5 13 427509, M62505, Hs 2161, complement component 5 rxeptor 1 (C5a 1, 7tm 1,TM=Y,SS=M, 512 423196, AK001866, Hs 125139, hypothetical protein FLJ11004, none,TM=M,SS=N, 5 12
433671, AW138797, Hs 132906, 19A24 protein, ιg,TM=M,SS=M, 5 11
426457, AW894667, Hs 380138, chimeπn (chimaerm) 1, DAG_PE-bιnd,RhoGAP,SH2,TM=M,SS=N, 506 431890, X17033, Hs 271986, integnn, alpha 2 (CD49B, alpha 2 εubuni, vwa,ιntegπn_A,FG-GAP,TM=Y,SS-M, 5 05 418185, AW958272, Hε 347326, intercellular adheεion molecule 2 (ICAM, none,TM=Y,SS=M, 505 437352, AL353957, Hε 284181 , hypothetical protein DKFZp434P0531 , DUF221 ,TM=Y,SS=M, 503 457918, AL359590, Hs 162604, hypothetical protein DKFZp762M186, PLDc,TM=M,SS=N, 502 452924, AW580939, Hs 97199, complement component C1q rxeptoπ EGF,lectιn_c,Tιsεue_tac,Xlιnk,TIL,TM=Y,SS=M, 502 426535, AU077012, Hs 288582, ESTε, Weakly similar to ubiquitous TPR m, Kunιtz_BPTI,Kunιtz_BPTI,7tm 2.HRM, 499 432805, X94630, Hs 3107, CD97 antigen, 7tm_2,EGF,GPS,FxCD,TM=Y,SS=M, 495 434883, AW381538, Hs 19807, hypothetical protein MGC12959, SH3,PH,WW,RhoGAP„ 495
414291, AI289619, Hs 13040, G protein-coupled receptor 86, 7tm_1,TM=Y,SS=M, 494 428981, BE313077, Hs 93135, ESTs, Weakly similar to ALU2_HUMAN ALU S, none.rrm, 492 451154, AA015879, Hs 33536, ESTε, TIMP.πoπe, 492
435730, AB020635 Hs 4984, KIAA0828 protein, AdoHcyase,Tιl A-N,2-Hxιd_DH C,TM=M,SS=N, 490 413011 , AW068115, Hs 821 , biglycaπ, LRR.LRRNT,, 490
422732, AA577455, Hs 24937, transformer-2 alpha (htra-2 alpha), rrm.ig, 489 417015, M83772, Hε 80876, flavin containing mon∞xygenaεe 3, FMO lιke,pyr_redox,TM=Y,SS=M, 4 88 412773, H15785, Hs 74573, similarto vxcinia virus Hindlll K4L OR, PLDc,TM=M,SS=N, 488 439659, AW970780, Hs 59483, leuctπe-πch repeat-containing G protein, 7tm_1 ,LRR,TM=Y,SS=N, 487 405102, , , C15001220* gι|4469558|gb]AAD21311 1| (AF, DAG_PE-bιnd,PH,RhoGEF,DC1„ 486
422795, AB033109, Hs 375610, KIAA1283 protein, 7tm_1,kazal,A2M,A2M_N,TM=Y,SS=M, 484 432581, AU076465, Hs 278441, KIAA0015 gene product, PP2C,TM=M,SS=N, 483
414936, C14774, , gb C14774 Clontxh human xrta polyA mRN, ank,pkmase,dealh,none, 482
430152, AB001325, Hs 234642, aquapoπn 3, MIP,TM=Y,SS=M, 482 444838, AV651680, Hs 208558, ESTs, ιntegπn_A,FG-GAP,none, 481
410423, AW402432, Hε 63489, protein tyroεine phosphatase, non-rxept, SH2,Y_phosphatase,DSPc,TM=M,SS=N, 481
453107, NM.016113, Hs 279746, vanilloid rxeptor-like protein 1, ank,ιon_trans,TM=Y,SS=N, 480
433376, AI249361, Hs 74122, caspase 4, apoptosis-related cysteine pr, CARD,ICE_p10,ICE_p20„ 480
422010, AA302049, Hs 31181, Homo sapiens cDNA FLJ23230 fis, clone C, none,SDF,sugar_tr, 478 419542, AA366037, Hε 90911 , εolute earner family 16 (monxarboxylic, none.none, 476
438899, AF085833, Hε 135624, ESTε, none,PI3 PI4_kιπaεe,PI3Ka,PI3K_C2,PI3K_rbd,PI3K_p85B, 475
427418, AA402587, Hs 356667, LAT1-3TM protein, none.none, 475
431924, AK000850, Hs 272203, Homo sapienε cDNA FLJ20843 fis, clone AD, SH3,none, 473
424218, AF031824, Hs 143212, cystatin F (leukxystatin), cyεtatiπ,, 472 414888, AL039185, Hε 77558, thyroid hormone rxeptor interxtor 7, HMG14_17,none, 472
416178, AI808527, Hs 192822, serologically defined breast cancer and, none,TM=M,SS=N, 471
430037, BE409649, Hs 227789, mitogen-xtivated protein kmase-xtivat, pkιnase,TM=M,SS=N, 471
451527, AF022813, Hs 26518, tranεmembrane 4 εuperfamily member 7, none.none, 471
453870, AW385001 , Hs 8042, Homo sapiens cDNA FLJ23173 fis, clone L, FG-GAP,ιntegππ_A,NIF, 471 408113, T82427, Hs 194101, Homo εapiens cDNA FLJ20869 fis, clone A, 7tm 3,πone, 470
438543, AA810141, Hs 192182, ESTs, SH2,pkιnase,none, 470
424943, AU077260, Hε 153924, death-asε∞iated protein kmase 1 , ank,pkιnase,death,SPRY,SAP,Rιbosomal_L24e,SRP54,dDENN,DENN,uDENN,TM=M,SS=N, 470
438113, AI467908, Hε 8882, ESTε, 7tm_1 ,none, 470
422164, NM.014312, Hs 112377, cortic al thymxyte rxeptor (X laevis , ιg,Gemιnι_mov,TM=Y,SS=M, 469 414482, S57498, Hs 76252, endothelin rxeptor type A, 7tm_1,TM=Y,SS=M, 469
425069, AA687465, Hs 298184, potassium voltage-gated channel, shaker-, aldo_keLred,πone, 467
432314, AA533447, Hs 285173, ESTs, Xlink none, 466
453518, AW503205, Hs 27268, gb UI-HF-BNO-akt-g-03-O-UI r1 NIH.MGC.50, SH3,PH,RhoGEF,TM=M,SS=N, 466
418613, AA744529, Hs 86575, mitogen activated protein kinase kinase , pkιnase,CNH,TM=M,SS=N, 466 446063, AI720140, Hs 151079, ESTs, ISK_Channel,none, 465
454034, NM.000691, Hs 575, aldehyde dehydrogenase 3 family, member , aldedh,, 465
431441, U81961, Hs 2794, sodium channel, nonvoltage-gated 1 alpha, ASC,TM=Y,SS=N, 465
443402, U77846, Hs 9295, elastin (supravalvular aortic stenosis, , none,PDZ,LIM,pkιπase, 465
414809, AI434699, Hs 77356, transferπn rxeptor (p90, CD71), PA,TM=Y,SS=N, 464 427535, R29543, Hε 2164, pro platelet baεic protein (includes pla, IL8,TM=M,SS=M, 464
437119, AI379921, Hs 177043, XP.171387 similar to rhotekin, none.none, 463
411779, AA292811, Hs 72050, non metastatic cells 5, protein expresse, NDK„ 463
429784, M89796, Hε 30, membrane εpann g 4-domaιns, subfamily A, none,TM=Y,SS=N, 462 415934, NM.000928 Hs 992, phospholipase A2, group IB (pancreas), phoslip,, 461 408873, AL046017, Hs 356216, calmodulm 2 (phosphorylase kinase, delt, none.none, 461 426432, AF001601 Hs 169857, paraoxonase 2, Arylesterase TM=M,SS=N, 459 444805, AB007899 Hε 12017, homolog of yeast ubiquitin protein ligas, WW,HECT,RNA_pol_A,πone, 459 408000, L11690, Hε 198689, bullous pemphigoid antigen 1 (230/240kD), efhand,spxtπn,GAS2,SH3,Plectιπ,RA Xylose_ιsom,FlιD,bZIP,Tropomyosιn,Myc-
LZ M,ldh_C,CH AIP3,TM=M,SS=N, 4 59 431087, H12723 Hs 290791, ESTs, lonjrans.none, 458
425465, L18964, Hε 1904 protein kmase C, iota, pkιnase,DAG_PE-bιnd,pkιπase_C,OPR TM=M,SS=N, 458 422427, AA310514, Hs 96692, ESTs, PH,Ets,CH,εpectrιπ,Ca_channel_B,none, 457 441527, W19504 Hε 7884, solute earner family 21 (organic amon , OATP_N,OATP_C,TM=Y,SS=N, 456
416464, NM 000132, Hs 79345, coagulation factor VIII, procoaguiant co, Cu-oxιdase,F5_F8_type_C„ 456 421233, AA209534, Hs 284243, tetraspan NET-6 protein, transmembrane4,TM=Y,SS=M, 456 422311, AF073515 Hs 114948, cytokine receptor-like factor 1, fn3,TM=M,SS=N, 4 55 444895, AI674383 Hs 22891, solute earner family 7 (cationic ammo , ASC,death,TNFR_c6, 455 428141, D50402, Hs 182611, solute earner family 11 (proton-coupled, Nramp,TM=Y,SS=N, 455
410290, AA402307, Hs 322844, hypothetical protein DKFZp564A176, Sema.PSI.TIG ιntegπn_B,TM=Y,SS=M, 454 426437, BE076537, Hs 169895, ubiquitin-coπjugating enzyme E2L 6, Armadιllo_seg,UQ_con,πoπe, 454 450086, AW016343, Hs 233301, ESTs, ank,death,ZU5,NMU,none, 4 54
438209 AL120659, Hε 6111, aryl hydrocarbon rxeptor nuclear transi, HLH,PAS,IL8,TM=M,SS=N, 454 414788, X78342, Hs 77313, cyclm-dependent kmase (CDC2-lιke) 10, pkιnase,TM=M SS=N, 453
429109, AL008637, Hs 196352, neutrophil cytosolic fxtor 4 (40kD), SH3 OPR PX,TM=M,SS=N, 453 427557, NM.002659, Hs 179657, plasminogen activator, urokmase recepto, UPAR_LY6,ET,PLA2_ιnh„ 453 411213, AA676939, Hs 69285, neuropilm 1, MAM,F5_F8_type_C,CUB,CUB,MAM,F5_F8_type_C, 453 434158, T86534, Hs 14372, ESTs, adenylatekmase.none, 452 431941, AK000106 Hs 272227, Homo sapienε cDNA FLJ20099 fiε, clone CO, pkmase.Fuπn lιke,Rxep_L_domaιn,none, 452
447341, AF106941, Hs 18142, arrestin, beta 2, arrestιn,arrestιn_C,PX,PH,PLDc, 452 447656, NM_003726, Hs 19126, src kmase-assxiated phosphoprotein of , SH3,PH,TM=M,SS=N, 451 417018, M16038, Hs 80887, v-yes-1 Yamaguchi εarcoma viral related , SH2,SH3,pkιπase,TM=M,SS=N, 451 422893, X98411, Hs 380077, myosin IF, SH3,myosιn_head,IQ,TM=M,SS=N, 451 407202, N58172, Hs 109370, ESTs, F5_F8_type_C,pkιnase,Ets,πone, 451
447079, AA280057, Hs 105280, ESTs, Weakly similar to dJ963K23 2 [H sa, zf-C2H2,zf C3HC4.UIM TM=M SS=N, 451 450747, AI064821, Hs 129953, ESTs, Highly similarto 1818357A EWS gen, rmn,zf-RanBP,GAS2 450 419452, U33635, Hs 90572, PTK7 protein tyrosine kinase 7, ιg,pkιnase,TM=Y,SS=M 450 453856, AA804789, Hs 379109, PDZ-LIM protein mystique, LIM,PDZ,TM=M,SS=N, 449 432744, AA988835 Hs 38664, ESTs, none.none, 449
419032, W81330, Hε 99877, ESTε, Highly similar to JAK3B (H εapienε, pkιnaεe,SH2,lnεulιn,pkιπase,SH2, 448 444009, AI380792, Hs 135104, ESTs, TNFR_c6,TIL none, 448
426416, AW612744 Hs 169824, killer cell lectm-like rxeptor subfami, lxtιn_c,TM=Y,SS=M, 448 412802, U41518, Hs 74602, aquapoππ 1 (channel-forming integral pr, MIP,TM=Y,SS=M, 448 447217, BE465754, Hs 17778 neuropilm 2, CUB MAM,F5_F8_type_C,TM=M,SS=M, 447
408771, AW732573, Hs 47584, potasεium voltage-gated channel, delayed, efhand,ιon_trans,K_tetra,none, 447 435049, AL122067, Hs 4746, hypothetical protein FLJ21324, none,TM=M,SS=N, 446 413278, BE563085, Hs 833, interferon εtimulated protein, 15 kDa, ubiquitin,, 445
423804, AW403448, Hs 1706, interferon stimulated transcnption fact, IRF,zf-C3HC4,IBR,zf-RanBP,TM=M,SS=N, 445 434308, N51517, Hs 47282, ESTs, pkιnase,pkιnase_C,none, 445
434448, W26667, Hs 184581, Homo sapiens cDNA FLJ14821 fis, clone OV, pkιnase,pkιnaεe_C„ 445 417426, NM_002291, Hε 82124, laminin, beta 1 , lamιnιn_EGF,lamιnιn_Nterm,ιntegππ_B„ 444 417389, BE260964, Hε 82045, midkiπe (neuπte growth-promoting fxtoπ PTN_MK,TM=M,SS=Y, 444 430259, BE550182, Hs 375142, RalGEF like protein 3, mouse homolog, th3,RA,RasGEF,TM=M,SS=M, 444 436001, AW903849, Hε 173840, HUEL(C4orf1)-ιnterxtιng protein, ιg,TM=M SS=M, 444
452355, N54926, Hε 29202, G protein-coupled rxeptor 34, 7tm_1,OATP_C,TM=Y,SS=N, 443 418751, BE389014, Hs 372548, phosphoιnoειtιde-3-kιnaεe, regulatory εu, SH2,noπe, 443 410068, AI633888, Hε 58435, FYN-binding protein (FYB-120/130), SH3,TM=M,SS=N, 443 449961, AW265634, Hε 133100, ESTs, pkιnase,Fuππ-lιke,Rxep_Ldomaιn,none, 442 451734, NM.006176, Hs 26944, neurograπm (protein kinase C substrate,, IQ,7tm_1,TM=M,SS=N, 442
410598, AI817130, Hs 9195, Homo sapiens cDNA FLJ13698 fis, clone PL, RasGEF.PRK, 442 439411 , AA044876, Hs 58043, ESTs, Weakly similar to CYA2_HUMAN ADENY, guaπylate_cyc,TM=Y,SS=M, 442 433179, AW362945, Hs 162459, ESTs, Armadillo.seg.πone, 442
414849, AW372721, Hs 291623, ESTs, Weakly similarto unnamed protein , pkinase.none, 442 409512, AW979187, Hs 293591, melanoma differentiation assxiated prot, DEAD,helιcase_C,CARD,TM=M,SS=N, 441
445903, AI347487, Hs 132781, class I cytokine rxeptor, fn3,TM=Y,SS=N, 441 438507, AA809052, Hs 356627, ESTs, none.none, 441
409524, AW402151, Hs 54673, tumor nxrosiε fxtor (ligand) εuperfami, TNF,TM=Y,SS=M, 440 453037, AA045175, Hε 17914, ESTε, none,TM=Y,SS=M, 440 412228, AW503785, Hs 73792, complement component (3d/Epsteιn Barr vi, sushι,TM=Y,SS=M, 440
451035, AU076785, Hs 430, plastin 1 (I isoform), efhand,CH,Adaptιn_N„ 440 415149, X12451, Hs 78056, cathepsin L, Peptιdase_C1„ 439
408105, AW152207, Hε 270977, ESTε, Weakly similar to 138022 hypotheti, Y_phosphataεe,carb_anhydrase,DSPc,none, 439 423099, NM.002837, Hs 123641, protein tyrosine phosphataεe, rxeptor t, fn3,Y_phosphatase,DSPc,COX6C,TM=M,SS=M, 439 438330, AW450572, Hs 257316, ESTs, pkmase,zf-C4,ERM,CNH,none, 439
433437, U20536, Hs 3280, caspase 6, apoptosis-related cysteine pπ ICE_p10,ICE_p20„ 439 429747, M87507, Hs 2490, caspaεe 1, apoptosis related cysteine pπ CARD,ICE_p10,ICE_p20„ 439 426410, BE298446, Hs 305890, BCL2-lιke 1, Bcl-2,BH4,none, 438 434511, R28982, Hs 18106, ESTs, pkιnase,Glyco_hydro_39, 438 448888, AW196663, Hε 200242, caεpase rxruitπient domain protein 6, CARD,TM=M,SS=N, 437
447827, U73727, Hs 19718, protein tyrosine phosphatase, rxeptor t, fn3,ιg,Y_phosphatase,MAM,TM=Y,SS=M 436 432583, AW023624, Hs 162282, potassium channel TASK4, potassium chan, ιon_trans,X,TM=Y,SS=M, 436 413472, BE242870, Hε 75379, solute earner family 1 (gliai high affi, SDF,TM=Y,SS=M, 436 426828, NM.000020, Hs 172670, activin A rxeptor type ll-like 1, pkιnase,Actιvιn_rxp,TM=M,SS=M, 436 449444, AW818436, Hs 351306, solute earner family 16 (monxarboxylic, none,TM=Y,SS=M, 436
437145, AF007216, Hs 5462, solute earner family 4 sodium bicarbon, HC03_cotransp,TM=Y,SS=N, 436
429670, L01087, Hs 211593, protein kinase C, theta, DAG PE-bιnd,pkιnase,pkιnase_C,DNA_pol_vιral_N,PHD,DC1,TM=M,SS=N, 435
421195, BE464560, Hs 133017, ESTs, none.none, 435 415758, BE270465, Hs 78793, protein kinase C, zeta, pkιnase,DAG_PE-bιnd,pkmase_C,OPR„ 435 457001 , J03258, Hs 2062, vitamin D (1 ,25- dihydroxyvitamiπ D3) re, hormone_rec,zf C4,Metallothιo_5,TM=M,SS=N, 434 419150, T29618, Hs 89640, TEK tyrosine kinase, endothelial (venous EGF,fn3,pkmase,ιg,lamιnιn_EGF,DSL,TM=Y,SS=M, 434 440675 AW005054 Hs 279788, ESTs, Weakly similar to KCCLHUMAN CALCI, pkinase none, 434 429657, D13626, Hs 2465, KIAA0001 gene product, putative G-protei, 7tm_1,TM=Y,SS=M, 434
414509, AW161311, Hs 76294, CD63 antigen (melanoma 1 antigen), transmembrane4,TM=Y,SS=M, 434 425771, BE561776, Hs 159494, Bruton agammaglobulinemia tyrosine kmas, SH2,SH3,pkmase,PH,BTK,TM=M,SS=N, 434 452124, AA454220, Hs 61170 ESTs, pkinase.none, 433
407775 NM 004914, Hs 38772, RAB36, member RAS oncogene family, ras,arf,TM=M,SS=N, 433 452688, AA721140, Hs 49930, ESTs, Weakly similarto putative p150 [H, SH3,none, 433
434164, AW207019, Hs 148135, seππe/threonme kinaεe 33, pkιnase,TM=M,SS=N, 432 445330, R52656, Hs 21691 ESTs, 7tm 1,none, 432 437527, AI241019, Hs 145644, ESTs, plP5K,none, 432
437763, AA469369, Hs 5831 , tiεsue inhibitor of metalloproteinase 1 , TIMP,pkmase,DAG_PE-bιnd,RBD, 431 416714, AF283770, Hs 79630, CD79A antigen (immunoglobulin-aεεxiated, ιg,ITAM,Zn_clus,TM=Y,SS=M, 431
416269, AA177138, Hs 161671, ESTs, pkιnaεe,DAG_PE-bιnd,RBD,πoπe, 430 425458, H89317, Hs 182889, ESTs, lon rans.none, 430
424206, NM.003734 Hs 198241, amine oxidase, copper containing 3 (vase, Cu_amιne_oxιd,Cu_amιne_oxιdN2,Cu_amιne_oxιdN3,TM=M SS=M 429 451876, T63141 , , gb yb99a12 s1 Stratagene lung (937210) H, SH3,none, 429 417801, AA417383, Hε 82582 integnn, beta like 1 (with EGF-like rep, EGF,, 429
435240, AI025435, Hs 117532, ESTs GHMP_kιnases,none, 427 444051, N48373, Hε 10247, xtivated leucxyte cell adhesion molxu, none.none, 426 423523, AW299828, Hs 193580, ESTs, none.none, 426
426274, D38122, Hs 2007, tumor necrosis factor (ligand) superfami, TNF,TM=Y,SS=N, 426 425356, BE244879, Hε 155939, moεitol polyphoεphate-5-phoεphataεe, 14, Exo_endo_phos,SH2,TM=M,SS=N, 426
448386, AB037750, Hs 21061, KIAA1329 protein, PKD,BNR,TM=Y,SS=M, 426 418318, U47732, Hs 84072, transmembrane 4 superfamily member 3, transmembrane4,TM=Y,SS=M, 426 427274, NM 005211, Hε 174142, colony stimulating fxtor 1 rxeptor, fo, ιg,pkιnase,TM=Y,SS=M, 426 416602, NM.006159, Hs 367895, Protein kinase C-bindmg protein NELL2, EGF,vwc,TSPN„ 425 436729, BE621807, Hs 351316, transmembrane 4 superfamily member 1, none,TM=Y,SS=M, 425
436494, AA720997, Hs 128295, ESTs, none,CAP_GLY,HC03_cotranεp,Glyco_hydro_63,PH, 424 439668, AI091277, Hs 302634, frizzled (Drosophila) homolog 8, Fπzzled,Fz,7tm_2,toxιn_2,TM=Y,SS=M, 424 418255, AW135405, Hs 37251, ESTs, pkinase.none, 424 400328, X87344, , transporter 2, ATP-bmding cassette, sub, none,TM=Y,SS=N, 424 405121 , , , mitogen activated protein kinase 8 inter, Cys knot,TGF-beta vwa vwc,vwd,TIL,DUF139 , 4 24
425795, AJ000479, Hs 159543, EDG-6 (endothelial differentiation, G-p, 7tm_1,TM=Y,SS=M, 423 406786, AW161678, Hs 111334, ferπtin, light polypeptide, ferπtm,TM=M,SS=N, 423 449843, R85337, Hs 24030, solute earner family 31 (copper transpo, none,TM=Y,SS=M, 423 445657, AW612141, Hs 279575, Homo sapienε G-protein coupled rxeptor , 7tm_1,TM=Y,SS=M, 423 413795, AL040178, Hs 142003, ESTs, none,pkιnase,LRR,LRRCT, 422
409142, AL136877, Hε 50758, SMC4 (structural maintenance of chromoso, ABCJran.M SMC_N,SMC_C,DUF164,none, 422 447887, AA114050 Hs 211610, caspase 8, apoptosis-related cysteine pπ ICE_p10,ICE_p20,DED TM=M,SS=N, 422 417318, AW953937, Hε 240845, ESTs, SH3,PH,RhoGEF„ 421 424291 , AL120051 , Hs 144700, ephnn B1 , Ephnn,TM=Y,SS=M, 421 408279, AF216965, Hs 44095, Homo sapiens, clone MGC 12617, mRNA, com, none.none, 420
432636, AA340864, Hs 278562, claudin 7, PMP22_Claudιn,TM=Y,SS=M, 4 20 424618, L29472, Hs 1802, major histxompatibility ∞mplex, claεs , ιg,MHC_ll_beta,TM-Y,SS-M, 4 19 445633, AI453386, Hε 17287, ESTs, Weakly similar to S26689 hypotheti, IRK,none, 419 432882, NMJ13257, Hs 279696, serum/glucxorticoid regulated kinase-li, pkιnase,PX,pkιnase_C„ 4 19 425481, AW978162, Hs 372811, ESTs, none.Oxysterol BP, 4 19
429061, Y14039, Hs 195175, CASP8 and FADD-like apoptosis regulator, ICE_p20,DED,TM=M,SS=N, 418 401083, , , NM 016582* Homo sapiens peptide transpoπ PTR2,TM=Y,SS=M, 4 18 420676, AI434780, Hε 4248 vav 2 oncogene, RhoGEF,PH,CH,SH2,SH3,DAG_PE-bιnd,none, 4 18 424377, AF081675, Hs 146322, killer cell Ixtm-like rxeptor εubfami, lxtιn_c,TM=Y,SS=M, 4 17 424148, BE242274, Hs 1741, integπn, beta 7, ιntegπn_B,EGF,metalthιo,PSI,TM=Y,SS=M, 4 17
421391, AW304350, Hs 191958, immunoglobulin superfamily rxeptor tran, ig.none, 4 17 452100, AI668668, Hs 379032, iπositol poιyphosphate-5-phoεphatase, 75, Exo_endo_phos,RhoGAP,none, 417 413969, X14034, Hs 75648, phospholipase C, gamma 2 (phosphatidylm, SH2,SH3,C2,PH,PI-PLC-Y,PI-PLC-X,PDGF„ 4 17 422310, AA316622, Hs 98370, cytxhrome P450, subfamily IIS, polypept, none,pkιnase,fn3,ιg, 4 17 444034, AL161957, Hs 10177, plxkstnn homology domain interacting p, E1-
E2_ATPase,Catιoπ_ATPase_C,Catιon_ATPase_N,Hydrolase,Rιbosomal_S15,bromodomaιn,WD40,TM=M,SS=N, 4 16 450056, BE047394, Hs 502, ESTs, Weakly similar to S71512 hypotheti, ABC_tran,ABC_membrane,ιg,MHC_ll_beta,SRP54,proteasome,ABC_membrane ABC tran, 4 16 407245, X90568, Hs 172004, titin, fπ3,ιg,SGXXSG,pkιnase,TM=M,SS=N, 4 16 418962, AA714835, Hs 271863, ESTs, RhoGAP,SH2,pkιnase,POLO_box,πone, 415 410590, BE615216, Hs 64746, chloride intracellular channel 3, none,TM=M,SS=N, 4 15 425743, BE396495, Hs 159428, BCL2 assxiated X protein, Bcl-2,TM=Y,SS=N, 415 446967, AI699629, Hs 156781, ESTs, none.none, 4 14 432176, AW090386, Hs 112278, arrestin, beta 1, arrestιn,arrestιn_C,noπe, 4 14 452571, W31518, Hs 34665, ESTs, none,TM=M,SS=N, 414 425421, L11669, Hs 157145, tetrxycline transporter-like protein, εugar_tr,TM=Y,SS=M, 4 14
410687, U24389, Hε 65436, lysyl oxidase-like 1, Lysyl oxidase,, 414 417871, AA521368, Hs 24252, ESTs, IBB,Armadιllo_seg,none, 413
429819, AL133011, Hs 253920, Homo sapienε mRNA, cDNA DKFZp434P201 (fr, none.none, 412 424522, AL134847, Hs 149957, πbosomal protein S6 kinase, 90kD, polyp, pkιnase,pkιnase_C„ 4 12 429623, NM_005308, Hs 211569, G protein-coupled rxeptor kinase 5, pkιπase,RGS,TM=M,SS=N, 4 12
413019, BE281604, Hs 75140, low density lipoprotein-related protein-, none,TM=M,SS=Y, 412 434071, AF116653 Hs 34192, Homo sapiens PRO0823 mRNA, complete eds, none,TM=M,SS=N, 4 11 434779, AF153815, Hs 50151, potasεium inwardly-rectifying channel, ε, IRK,TM=Y,SS=N, 4 11 449656, AA002008, Hs 188633, ESTs, PIP5K none, 411 406403, , , NM.002162* Homo sapiens intercellular ad, ιg,TM=Y,SS=M, 4 10
427732, NM_002980, Hs 2199, εxretin receptoπ 7tm 2,HRM,TM=M,SS=M, 4 10
437608, AA761605, Hs 292308, ESTs, Weakly similar to ALULHUMAN ALU S, pkιnase,RI01,none, 4 10
432885, AA595607, Hε 368129, ESTs, Weakly similar to ALULHUMAN ALU S, pkιnase,pkιnase_C,none, 4 10
Figure imgf000520_0001
428713, AA432067, Hs 268551, ESTs, Moderately similarto CYA4 RAT ADE, pkinase,, 389
456629, AW891965, Hs 367942, histone deacetylase 3, HSP90,HATPase_c,zf C2H2,PHD,πone, 389
425190, AW028302, Hs 155079, protein phosphatase 2, regulatory εubuni, B56,TM=M,SS=N, 389
426752, X69490, Hs 172004, Mm, fπ3,ιg,pkιnase,SGXXSG,TM=M,SS=N, 389 417767, BE242241, Hs 82542, acyloxyacyl hydrolase (neutrophil), Lιpase_GDSL,TM=M,SS=M, 388
414029, BE297731, Hs 75709, maπnose 6-phosphate receptor (cation dep, Man 6-P_recep,TM=M,SS=M, 388
416140 AI918035 Hs 301198, roundabout (axon guidance receptor, Dros, none none, 388
434224, AA380731, Hs 84, interleukin 2 receptor, gamma (severe co, fn3,TM=Y,SS=M, 388
410011, AB020641, Hs 57856, PFTAIRE protein kinase 1, pkιnase,TM=M,SS=N, 387 406908, Z25437, , gb H sapiens protein-tyrosine kinase gen, none none, 387
425289, AW139342, Hε 155530, interferon, gamma-mducible protein 16, PAAD.DAPIN.HIN,, 387
441859, AW194364, Hs 9877, ιnterleukιπ-4 induced gene-1 protein (FI, Amιπo_oxιdase,FAD_bιπdιng_3,TBC,TM=M,SS=N, 387
439975, AW328081, Hs 6817, inosine tπphosphatase (nuclxside tπph, Hamlp lιke,TM=M,SS=N, 387
415392, Z44067, Hε 10957, ESTε, PIP5K,none, 386 416033, NM.012201, Hε 78979, Golgi apparatuε protein 1, cys_πch_FGFR,TM=Y,SS=M 386
414649, AI672727, Hs 76753, endoglin (CD105 antigen) (ENG), πone,TM=Y,SS=M, 385
425729, L22647, Hs 159360, prostaglandin E receptor 1 (subtype EP1), 7tm_1,TM=Y,SS=M, 385
414496, W73853, Hε 355424, ESTε, pkιnaεe,F5_F8_type_C,adh_εhort,πone, 384
412204, AI125507, Hs 24937, ESTs, ig.rrm.noπe, 384 434375, BE277910, Hs 3833, 3'-phosphoadenosιne 5'-phosphoεulfate εy, APS_kmase,ATP-8ulfurylase,PRK,Thymιdylate_kιn„ 384
444981, AW855398, Hs 12210, hypothetical protein FLJ13732 similar to, SH2,TM=M,SS=N, 384
412309, M23892, Hs 73809, arachidonate 15-Iιpoxygenase, lipoxygenase.PLAT,, 384
405545, , , Target Exon, ABC_tran,SRP54,ABC_membrane,TM=Y,SS=M, 384
407143, C14076, Hs 332329, EST, none,TM=Y,SS=M, 384 420593, AA280356, Hs 187634, ESTs, B56,noπe, 384
413420, AW410235, Hs 75348, proteasome (prosome, macropain) activato, PA28_alρha,PA28_beta,bιoptenn_H„ 383
448253, H25899, Hs 201591, ESTs, 7tm_2,HRM,none, 383
444042, NMJ04915, Hs 10237, ATP-bmding cassette, sub-family G (WHIT, ABC_tran,PRK,GBP,TM=Y,SS=N, 383
430397, AI924533, Hs 105607, bicarbonate transporter related protein , HC03_cotranεp,TM=Y,SS=N, 383 423067, AA321355, Hs 285401, colony stimulating factor 2 receptor, be, fn3,TM=Y,SS=M, 383
458188, AW297226 Hε 137840, ESTε, Moderately similarto SIX4_HUMAN H, pkιnase,WD40, 382
426486, BE178285, Hs 170056, Homo sapienε mRNA, cDNA DKFZp586B0220 (f, pkinase.none, 382
428791, AA435661, Hs 264750, ESTs, zf-C3HC4,none, 382
438068, AI927209, Hs 306210, Homo sapiens cDNA FLJ23133 fis, clone L, NusG,, 382 453370, AI470523, Hs 139336, ATP-b ding cassette, sub-family C (CFTR ABC tran ABC_membrane,TM=Y,SS=N, 382
419250, AW770185, Hs 356066, U5 snRNP-spxific protein, 116 kD, 7tm_1 ,BAH,zf CXXC,DNA_methylase, 382
410017, AW952426, Hs 109438, Homo sapiens clone 24775 mRNA sequence, none.none, 382
420679, X57152, Hs 165843, fibπllanπ, CK II beta,Fιbπllaπn,WD40,TM=M,SS=N, 382
417916, NMJ06416, Hs 82921, solute camerfamily 35 (CMP-sialic aci, DUF6,TM=Y,SS=M, 381 425923, NMJ05026, Hs 162808, phosphoιnosιtιde-3-kmase, catalytic, de, none.none, 381
417365, D50683 Hs 82028, transforming growth factor, beta rxepto, pkιnase,WD40,TM=Y,SS=N, 364
414521, D28124, Hε 76307, neurablastoma, εuppression of tumoπgeπi, DAN,TM=M,SS=M, 352
422398, AI476149, Hs 334489, hypothetical protein FLJ21992, SH2.SH3,, 351
418432, M14156, Hε 85112, inεulm-like growth factor 1 (somatomedi, Insulin,, 350 459705, BE082764 Hs 270252, ESTs, Weakly similar to androgen rxepto, none,C2,WW,HECT, 348
425009, X58288, Hs 154151, protein tyrosine phosphatase, rxeptor t, fπ3,ιg,Y_phosphatase,MAM,TM=Y,SS=M, 338
415817, U88967, Hs 78867, protein tyrosine phosphatase, receptor-t, fn3,Y_phosphataεe,cart>_anhydrase,TM=Y,SS=M, 337
433336, AF017986, Hε 31386, sxreted fnzzled-related protein 2 (stπ Fz,NTR„ 324
426125, X87241, Hε 166994, FAT tumor suppressor (Drosophila) homolo, EGF,cadheπn,lamιnιn_G,TM=Y,SS=M, 3 11 419721, NM_001650, Hs 315369, aquapoπn 4, MlP.none, 299
433147, AF091434, Hε 43080, platelet denved growth fxtor C, PDGF.CUB,, 291
417976, BE565892, Hs 83077, interleukin 18 (mterferon-gamma-inducin, none,TM=M,SS=N, 289
439180, AI393742, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Fuπn-lιke,pkιnase,Rxep_L_domaιn,Fuππ-lιke,pkιnase,Rxep_L_domaιn,Peptιdase_M24, 259 426158, NMJ01982, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Fuππ like.pkmase.Rxep L domain.Furin lιke,pkιnase,Recep L_domaιn,Peptιdase_M24, 223 411089, AA456454, Hs 355702, cell diviεion cycle 2-lιke 1 (PITSLRE pπ none.none, 207
428800, M57627, Hs 193717, interieukin 10, IL10„ 1 10
TABLE 40B Pkey Unique Eos probeεet identifier number
CAT number Gene cluster number Accession Genbank xcesεion numbers
Pkey CAT Number Acceεsion 5
456034 685586 1 AA136653 AA136656 AW450979 AA984358 AA809054 AW238038 AA492073 BE168945 459702 539529J BG207209 BE166299 AI204995 BG199355 AW969908 AA528756 AW440776 BI044354 432222 539529J BG207209 BE166299 AI2049958G199355 AW969908 AA528756 AW440776 BI044354 414991 1785136 1 D78831 C17898 D78863 0 409745 MH1944_5 BI030997 AA921874 AW188822 BI027862 AI347618 AI361453 AI088754 AW207491 AA077391 BG012775 BG997382 AA286833 AA150722 BI007625
BI027864 BI009100 BI006275 BI006270 BI031000 BI029864 BI006277 BI007627 BI006266 BI006991 BI006990 BI007763 BI007762 BG997377
AA150780 BI033518 BI027818 BG015789 BI033807 AA341445
414936 1782849J C14774 C17911 D79033 451876 2328579 1 T63141 AI821021 BF370092 BF370127 BF370060 T62998 5 432639 1237887J AW973785 H60163AA557608
TABLE 40C
. Pkey Unique number correεpondmg to an Eoε probeset U Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I etal , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons Pkey Ref Strand NLposition
402474 7547175 Minus 53526-53628,55755 55920,57530-57757
404240 5002624 Minus 116132-116407,116653-116922
405102 8076881 Minus 120922-121296
405121 8102330 Minus 35816-36004,36587-36684
401083 3242744 Plus 33192-33360
406403 9256305 Minus 151426-151680
402550 7652009 Minus 80413-80673
405545 1054740 Plus 118677-118807,119091-119296,121626-12182
TABLE 41A 556 GENES UP-REGULATED IN PANCREATIC TUMORS OR PANCREATITIS RELATIVE TO NORMAL TISSUES
Table 41 A lists about 556 genes up-regulated in pancreatic tumors or pancreatitis relative to normal tisεues These genes were selxted from 59680 probeεetε on the Eos/Affymetnx Hu03 Genechip array
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of pancreatic cancer/median of normal pancreas
Pkey ExAccn UnigenelD Unigene Title "RT
412228 AW503785 Hs 73792 complement component (3d/Epsteιn Barr vi 725
431462 AW583672 Hs 256311 granm like neuroeπdocnne peptide precu 1 64
444995 AJ272265 Hs 12230 secreted phosphoprotein 2, 24kD 3 58
453863 X02544 Hε 572 orosomucoid 1 114 18
441031 AI110684 Hs7645 fibπnogen, B beta polypeptide 92240
421344 AW631030 Hs 103665 villin-like 219
416018 AW138239 Hs 78977 proprotein ∞nvertase subtilisin/kexm t 61 10
438091 AW373062 Hs 83623 nuclear receptor subfamily 1, group I, m 607 40
418888 AU076801 Hs 89436 cadhenn 17, LI cadhenn (liver-mteεtin 22820
418969 W33191 Hs 28907 hypothetical protein FLJ20258 497
443162 T49951 Hs 9029 DKFZP434G032 protein 3801
423096 AA732684 Hs 278428 progeεtm induced protein 18960
413719 BE439580 Hs 75498 εmall inducible cytokine subfamily A (Cy 11 06
448243 AW369771 Hs 52620 integnn, beta 8 11690
421044 AF061871 Hs 311736 Human DNA sequence from clone RP1-238D15 21 52
407788 BE514982 Hs 38991 S100 calcium binding protein A2 874
422867 L32137 Hs 1584 cartilage oligomeπc matnx protein (COM 311
432467 T03667 Hs 239388 Human DNA sequence from clone RP1-304B14 30770
457059 BE561665 Hs 177677 exosome component Rrp40 33 60
451945 BE504055 Hs 211420 ESTs 731
453354 W55946 Hs 234863 Homo sapienε cDNA FLJ 12082 fiε, clone HE 13370
443247 BE614387 Hs 333893 c-Myc target JP01 349 10
410132 NM 003480 Hs 300946 Microfibπl-aεεxiated glycoproteιπ-2 33000
416984 H38765 Hs 80706 diaphorase (NADH/NADPH) (cytxhrome b-5 378
413835 AI272727 Hs 249163 fatty xid hydroxylase 353
433790 BE298215 Hs 288968 RAB22A, member RAS oncogene family 7390
414774 X02419 Hs 77274 plaεmmogen xtivator, urokinaεe 339
410639 BE269047 Hs 65234 hypothetical protein FLJ20596 1 72
410541 AA065003 Hs 64179 εyπtenιn-2 protein 1029
427722 AK000123 Hs 180479 hypothetical protein FLJ20116 679
429612 AF062649 Hs 252587 pituitary tumor-transforming 1 462
407604 AW191962 Hs 249239 collagen, type VIII, alpha 2 36630
431193 AW749505 Hs 296770 KIAA1719 protein 699
442080 AW444761 Hs 44565 ESTs 11800
427670 BE612888 Hs 180224 myosin regulatory light chain 273
446921 AB012113 Hs 16530 small inducible cytokine subfamily A (Cy 64730
419551 AW582256 Hs 91011 anteπor gradient 2 (Xenepus laevis) hom 73890
441633 AW958544 Hs 112242 normal mucosa of esophagus spxific 1 6843
407792 AI077715 Hs 39384 putative sxreted ligand homologous to f 303
419216 AU076718 Hs 164021 small inducible cytokine subfamily B (Cy 773
416913 AW934714 gb RC1-DT0001-031299-011-a11 DT0001 Homo 22730
418384 AW149266 Hs 25130 Homo sapiens cDNA FU14923 fis, clone PL 11560
452355 N54926 Hs 29202 G protein-coupled rxeptor 34 19220
419481 AI879195 Hs 90606 15kDaselenoproteιn 11990
407230 AA157857 Hs 182265 keratin 19 12 11
418526 BE019020 Hs 85838 εolute camerfamily 16 (monxarboxylic 663
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph 592 10
411498 NM 014210 Hs 70499 ecotropic viral integration site 2A 12040
445517 AF208855 Hs 12830 hypothetical protein 11740
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontm, 425
428385 AF112213 Hs 184062 putative RabS-interacting protein 312
448663 BE614599 Hs 106823 hypothetical protein MGC14797 135 20
406867 AA157857 Hs 182265 keratin 19 11 32
417426 NM 002291 Hs 82124 laminin, beta 1 406 20 406366 AF026692 Hs 105700 secreted frizzled related protein 4 062
401201 #(NOCAT) Target Exon 075
420767 AF072711 Hs 99918 carboxyl ester lipase (bile salt stimula 063
405556 Y09306 Hs 30148 homeodomain interacting protein kinaεe 3 075
442776 AW959498 Hs 8709 chymotrypsin C (caldxπn) 067
405555 Y09306 Hs 30148 homeodomain iπterxt g protein kinaεe 3 083
403207 #(N0CAT) C2000960 gι!131432|εp|P23132|LITH_BOVIN 080
427858 NM 001971 Hs 21 elastase 1 , pancreatic 098
426004 AW600300 Hs 124123 ESTs, Moderately similar to SYNL RAT SYN 088
401541 NA Target Exon 091
429793 AI417638 Hs 114648 estrogen regulated gene 1 085
423068 M25629 Hs 123107 kallikrein 1 renal/pancreas/salivary 081
433110 D56494 Hs 3191 rat regenerating islet deπved like hum 072
425988 BE045897 Hs 274454 ESTs Weakly similar to I38022 hypotheti 095
416768 AA363733 Hs 1032 regenerating islet denved 1 alpha (pane 087
412470 M93283 Hs 73923 pancreatic lipase related protein 1 089
431969 AA366217 Hs 2879 carboxypeptidase A1 (pancreatic) 097
419219 AW583139 Hs 89717 carboxypeptidase A2 (pancreatic) 095
412688 AW583062 Hs 74502 chymotrypsinogen B1 095
427811 M81057 Hs 180884 carboxypeptidase B1 (tissue) 1 07
420937 AW966719 Hs 1340 colipase pancreatic 099
418068 AW971155 Hs 293902 ESTs Weakly similar to ISHUSS protein d 1 02
410839 NM.006849 Hs 66581 protein disulfide lεomerase 1 00
437986 AA774575 Hs 121776 testis expressed sequence 11 1 02
415934 NM_000928 Hs 992 phospholipase A2, group IB (pancreas) 1 06
427965 D00306 Hε 181289 elastase 3, pancreatic (protease E) 1 22
406399 #(NOCAT) NM.003122 Homo sapienε serine protease 1 08
426230 AA367019 Hε 241395 protease seπne, 1 (trypsin 1) 1 11
414061 NM 000699 Hs 300280 amylase, alpha 2A pancreatic 1 22
421243 AW873803 Hs 102876 pancreatic lipase 1 13
419263 AW583874 Hs 89832 insulin 1 12
424208 AW583123 Hs 143113 pancreatic lipase related protein 2 1 13
408983 NM 000492 Hs 663 cystic fibrosis transmembrane conductanc 1 32
436217 T53925 Hs 107 fibnnogen like 1 1 72
435975 AL118990 Hs 41997 alpha 1 B glycoprotein 1 60
431330 X69532 Hs 2777 inter-alpha (globulin) inhibitor, H1 pol 202
414463 T69078 Hs 76177 alpha-1-mιcroglobulιπ/bιkunιn precursor 1 82
415003 M11437 Hs 7741 kininogen 383
422281 M36803 Hs 1504 hemopexm 2 14
414910 X12662 Hε 289057 arginase liver 9790
417296 L36196 Hε 81884 εulfotranεferase family, cytosolic 2A 23670
400836 #(NOCAT) Target Exon 247
452983 L32140 Hε 531 afamiπ 117 10
419768 T72104 Hs 93194 apolipoprotein A-l 487
413841 M34276 Hs 75576 piaεmmogen 37400
400560 #(NOCAT) NM_030878* Homo sapiens cytxhrome P450, 14450
419502 AU076704 Hs 90765 fibnnogen A alpha polypeptide 26650
425746 NM.001701 Hs 159440 bile xid Coenzyme A ammo xid N xylt 7780
426205 D63521 Hs 167877 leukxyte cell-deπved chemotaxin 2 169 80
414590 NM.000506 Hs 76530 coagulation fxtor II (thrombin) 360
443614 AV655386 Hε7645 fibπnogen, B beta polypeptide 40040
429023 NM 000312 Hs 2351 protein C (inxtivator of coagulation fa 472
428311 NM.005651 Hs 183671 tryptophan 2,3-dιoxygenase 526
425260 L47726 Hs 1870 phenylalanine hydroxylase 7378
443316 AI478463 Hs 18443 aldehyde dehydrogenase 8 family, member 18220
413318 AU076607 Hs 75285 inter-alpha (globulin) inhibitor, H2 pol 33500
413829 NM.001872 Hs 75572 carboxypeptidase B2 (plasma) 17340
421126 M74587 Hs 102122 insulin like growth fxtor binding prote 56530
407731 NM 000066 Hs 38069 complement component 8, beta polypeptide 8620
413585 AI133452 Hs 75431 fibπnogen, gamma polypeptide 47720
452624 AU076606 Hs 30054 coagulation fxtor V (proxcelenn, labi 201 50
416402 NM 000715 Hs 1012 complement component 4-bιndιng protein, 426 10
425573 AB006423 Hs 158308 senne (or cysteine) proteinase inhibito 1 10
421905 AI660247 Hs 32699 ESTs, Weakly similar to UV-1 protem [H 062
406672 M26041 Hs 198253 major histxompatibility complex, class 402
431369 BE184455 Hs 251754 sxretory leukxyte proteaεe inhibitor ( 534
421712 AK000140 Hs 107139 hypothetical protein 562
417233 W25005 Hs 24395 εmall inducible cytokine subfamily B (Cy 885
442896 R37725 Hs 261108 ESTs 15770
410566 AA373210 Hs 43047 Homo sapiens cDNA FLJ13585 fis, clone PL 13770
428486 AW583497 Hs 184604 pancreatic polypeptide 259
457489 AI693815 Hs 127179 cryptic gene 3 23
404866 NA ENSP00000251112* Sodium/potassium transp 2 84
432874 W94322 Hε 279651 melanoma inhibitory activity 248
445891 AW391342 Hs 199460 ESTs 7038
404682 NA C9001188* gι|12738842|ref|NP_073725 1| p 1 38
429547 AW009166 Hs 99376 ESTs 685
441085 AW136551 Hs 181245 Homo sapiens cDNA FLJ12632 fis clone NT 521
422397 AJ223366 Hε 116051 Homo sapiens cDNA FLJ22495 fis, clone H 1 74
446868 AV660737 Hs 135100 ESTs 102 10
404287 NA C6001909 gι|704441|dbj|BAA189091| (D298 24270
443267 AW450630 Hs 133851 ESTs 98 90
451635 AA018899 Hs 127179 cryptic gene 2 16 417801 AA417383 Hs 82582 integnn beta like 1 (with EGF-like rep 131 70
414142 AW368397 Hs 150042 Homo sapiens cDNA FLJ14438 fis, clone HE 12870
425921 NM 007231 Hs 162211 εolute earner family 6 (neurotranεmitte 9290
410309 BE043077 Hs 278153 ESTs 10880
425842 A1587490 Hs 159623 NK-2 (Drosophila) homolog B 170 10
431938 AA938471 Hs 54431 spxific granule protein (28 kDa) cyste 7570
449592 A1655494 Hs 195718 ESTs 458
414259 W44633 Hs 301296 Homo sapiens cDNA FLJ23131 fis clone L 18850
406685 M18728 gb Human nonspecific crosεreactmg antig 112360
411573 AB029000 Hs 70823 KIAA1077 protein 99560
429201 X03178 Hs 198246 group-specific component (vitamin D bind 11 32
418318 U47732 Hs 84072 transmembrane 4 superfamily member 3 8 38
428698 AA852773 Hs 334838 KIAA1866 protein 66200
444754 T83911 Hs 11881 transmembrane 4 superfamily member 4 400
432596 AJ224741 Hs 278461 matπlin 3 28350
428824 W23624 Hs 173059 ESTs 455
444006 BE395085 Hs 10086 type 1 transmembrane protein Fn14 301
424971 AA479005 Hs 154036 tumor suppresεmg subtransferable candid 421
418394 AF132818 Hs 84728 Kruppel like fxtor 5 (intestinal) 480
448844 AI581519 Hε 177164 ESTs 36280
420908 AL049974 Hs 100261 Homo sapiens mRNA, cDNA DKFZp564B222 (fr 13390
423685 BE350494 Hε 49753 uveal autoantigen with coiled coil domai 128 20
428392 H10233 Hs 2265 secretory granule neuroendxnπe protei 13 83
429597 NM 003816 Hs 2442 a disintegnn and metalloprotemase doma 31600
452571 W31518 Hs 34665 ESTs 24550
443646 AI085198 Hs 164226 ESTs 18940
436032 AA150797 Hs 109276 latexin protein 291 10
448030 N30714 Hs 325960 membrane εpannmg 4-domaιns subfamily A 25220
422109 S73265 Hs 1473 gastnn releasing peptide 27820
430407 H23551 Hs 30974 ESTs 620
419235 AW470411 Hs 288433 neurotπmiπ 42350
449048 Z45051 Hs 22920 similar to S68401 (cattle) glucose indue 401
444301 AK000136 Hs 10760 asponn (LRR clasε 1) 49990
427333 AF067797 Hs 176658 aquaponn 8 1 05
417931 W95642 Hs 82961 trefoil factor 3 (intestinal) 433
407777 AA161071 Hs 71465 squalene epoxidase 364
435652 N32388 Hs 334370 uncharactenzed hypothalamus protein HBE 1 47
421341 AJ243212 Hs 279611 deleted in malignant brain tumors 1 398
453935 AI633770 Hs 42572 ESTs 208
431629 AU077025 Hs 265827 interferon, alpha-inducible protein (clo 384
439737 AI751438 Hs 41271 Homo sapiens mRNA full length insert cDN 1421
426227 U67058 Hs 168102 Human proteinase xtivated rxeptor 2 mR 31570
413554 AA319146 Hs 75426 sxretograniπ II (chromograπin C) 853
412104 AW205197 Hε 240951 Homo εapienε, Similar to RIKEN cDNA 2210 313
410310 J02931 Hs 62192 coagulation fxtor III (thromboplaεtm, 933
440484 BE328156 Hs 150356 ESTs 1 03
447395 AI418412 Hs 184793 Homo sapienε cDNA FLJ21880fis clone H 1 09
440099 AL080058 Hs 6909 DKFZP564G202 protein 1474
434665 AA642125 gb nrδ0c01 s1 NCI_CGAP_Lym3 Homo εapiens 098
452194 AI694413 Hs 332649 olfactory rxeptor, family 2, subfamily 223
408915 NM 016651 Hs 48950 heptacellular carcinoma novel gene-3 pro 32940
424411 NM 005209 Hs 146549 crystallin, beta A2 1 71
426575 M74826 Hs 170808 glutamate dxarboxylase 2 (pancreatic is 269
445417 AK001058 Hs 12680 Homo sapiens cDNA FU10196 fis, clone HE 1 70
426322 J05068 Hε 2012 transcobalamin I (vitamin B12 binding pr 319
429010 Y18198 Hε 194725 one cut domain, family member 2 1 96
414420 AA043424 Hε 76095 immediate early response 3 254
422565 BE259035 Hs 118400 singed (Drosophιla)-lιke (εea urchin faε 330
414004 AA737033 Hs 7155 ESTε, Moderately similar to 2115357ATYK 31280
441350 AB020690 Hε 7782 paraneoplastio antigen MA2 17780
406173 #(NOCAT) ENSP00000250148* Growth hormone vaπant 146
403776 #(NOCAT) ENSP00000226542' Small inducible cytokm 121 80
403574 NA Target Exon 16 12
428832 AA578229 Hε 324239 ESTs, Moderately similar to ZN91 HUMAN Z 394
458449 H04482 Hε 29019 ESTs 71 60
409958 NM_001523 Hε 57697 hyaluronan synthase 1 1 77
437100 AI761073 Hs 14535 Homo sapiens cDNA FLJ22314 fis, clone H 313
451181 AI796330 Hs 207461 ESTs 6800
440508 BE267911 Hs 196970 ESTs 3800
429636 AA455692 Hs 163232 ESTs 3070
419570 W68738 gb zd37g06 s1 Soares_fetal_heart_NbHH19W 1 02
431779 AW971178 Hs 268571 apolipoprotein C-l 336
431723 AW058350 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 1020
428330 L22524 Hs 2256 matnx metalloprotemase 7 (MMP7, uteπn 394
423961 D13666 Hs 136348 osteoblast spxific factor 2 (fascidin 1171 10
414359 M62194 Hs 75929 cadhenn 11, type 2, OB-cadheπn (ostxb 80950
440482 AA886658 Hs 50873 ESTs 9 95
414602 AW630088 Hs 76550 Homo sapiens mRNA, cDNA DKFZp564B1264 (f 3070
423401 NM.001992 Hs 128087 coagulation fxtor II (thrombin) rxepto 8290
452239 AW379378 Hs 170121 protein tyroεine phosphatase, rxeptor t 2601
433364 AI075407 Hs 296083 ESTs, Moderately similar to I54374gene 538
409335 NM.001502 Hs 53985 glycoprotein 2 (zymogen granule membrane 054
420876 AA918425 Hs 177744 ESTs 089 430154 AW583058 Hs 234726 serine (or cysteine) proteinase inhibito 094
401732 #(N0CAT) NM.001176* Homo sapiens Rho GDP disεxia 1 13
404142 NA Target Exon 1 33
424165 AW582904 Hs 142255 islet amyloid polypeptide 295
413880 AI660842 Hs 110915 interleukin 22 receptor 1 34
407007 U22961 gb Human mRNA clone with similarity to L 1 57
426300 U15979 Hs 169228 delta like homolog (Drosophila) 1 48
432855 AF017988 Hs 279565 secreted fπzzled related protein 5 1 28
424503 NM 002205 Hs 149609 integnn, alpha 5 (fibronectin receptor, 1 31
445730 AI624342 Hs 170042 ESTs 214
406666 V00495 Hs 184411 albumin 295
435849 BE305242 Hs 16098 claudin 2 1 96
426784 U03749 Hs 172216 chromogranm A (parathyroid secretory pr 249
430272 X04898 Hs 237658 apolipoprotein A-ll 329
412374 X01388 Hs 73849 apolipoprotein C-lll 242
419276 BE165909 Hs 306881 MSTP043 protein 8340
415448 T68645 Hs 952 solute carrier family 10 (sodium/bile ac 352
423541 AA296922 Hs 129778 gastrointestinal peptide 316
428355 BE256452 Hs 2257 vitronxtin (serum spreading factor, som 624
425551 AA359252 Hs 126485 hypothetical protein FLJ12604, KIAA1692 1467
455630 AV655701 Hs 75183 cytochrome P450, subfamily HE (ethanol 430
428786 Y16577 Hs 2314 mannose binding lectin (protein C) 2, εo 9210
420726 K02402 Hs 1330 coagulation factor IX (plasma thrombopla 20330
451253 H48299 Hs 26126 claudin 10 1 37
420923 AF097021 Hs 273321 differentially expresεed in hematopoieti 338
413881 L00190 Hs 75599 εenne (or cyεteme) proteinase inhibito 704
431930 AB035301 Hs 272211 cadhenn 7, type 2 584
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 265
419354 M62839 Hs 1252 apolipoprotein H (beta 2-glycoproteιn I) 928
422237 M13149 Hs 1498 histidine rich glycoprotein 3426
437145 AF007216 Hs 5462 solute camerfamily 4, sodium bicarbon 1 92
414386 X00442 Hs 75990 haptoglobin 832
425247 NM 005940 Hs 155324 matnx metalloproteinase 11 (MMP11, stro 174
452689 F33868 Hs 284176 transferrin 651
436624 T64297 Hs 5241 fatty acid binding protein 1, liver 3508
409187 AF154830 Hs 50966 carbamoyl-phosphate synthetase 1, mitoch 17030
428874 W32133 Hs 194366 transthyretin (prealbumiπ, amyloidosis t 234
405849 #(NOCAT) Target Exon 103 10
405281 #(NOCAT) NM.002864 Homo sapiens pregnancy-zone pr 31 20
419078 M93119 Hs 89584 insulinoma-assxiated 1 628
422095 AI868872 Hs 282804 hypothetical protein FU22704 289
425834 NM.001639 Hs 1957 amyloid P component, serum 380
452304 AA025386 Hε 61311 ESTs, Weakly similar to S10590 cysteine 1 82
407244 M10014 Hε 75431 fibπnogen, gamma polypeptide 13 15
450400 AI694722 Hε 279744 ESTs 5 22
413916 N49813 Hs 75615 apolipoprotein C-ll 860
444632 AI184027 Hs 146986 ESTs, Weakly similar to FATH.HUMAN CADHE 71 30
415906 AI751357 Hs 288741 Homo sapienε cDNA FLJ22256 fis, clone H 1 70
410197 NM.005518 Hs 59889 3-hydroxy-3-methylglutaryl-Coenzyme A sy 465
417366 BE185289 Hs 1076 small prolme-nch protein 1B (cornifin) 301
436961 AW375974 Hs 156704 ESTs 16460
446319 AW207590 Hs 160711 ESTs 1 88
427899 AA829286 Hs 332053 serum amyloid A1 698
419092 J05581 Hs 89603 mucin 1, transmembrane 212
421515 Y11339 Hs 105352 GalNAc alpha-2, 6-sιalyltraπsferase I, I 13220
452340 NMJ02202 Hs 505 ISL1 transcnption fxtor, LlM homxdoma 623
406319 NA CX000780 gι|6679197|ref|NP 032800 1| pol 51 50
404286 NA C6001909 gι|704441|dbj|BAA18909 1| (D298 1 75
419183 U60669 Hε 89663 cytxhrome P450, subfamily XXIV (vitamin 5290
406293 NA Target Exon 6830
431912 AI660552 Hs 154903 ESTs, Weakly similar to A56154 Abl subεt 10243
409327 L41162 Hs 53563 collagen, type IX, alpha 3 20630
425200 BE255203 Hs 155101 ATP εyπthaεe, H transporting, mitxhondr 576
418738 AW388633 Hs 6682 solute earner family 7, (cationic am o 200 10
416661 AA634543 Hs 79440 IGF-II mRNA-binding protein 3 9770
434699 AA643687 Hs 149425 Homo sapiens cDNA FLJ11980 fis, clone HE 396
429921 AA526911 Hs 82772 collagen, type XI, alpha 1 3000
428758 AA433988 Hs 98502 hypothetical protein FU14303 466
446998 N99013 Hs 16762 Homo sapienε mRNA, cDNA DKFZp564B2062 (f 19380
418478 U38945 Hs 1174 cyclm-dependent kinase inhibitor 2A (me 305
420001 J05064 Hs 1282 complement component 6 15900
449038 AL133084 Hs 22908 Homo sapienε mRNA, cDNA DKFZp434J1027 (f 39 10
423184 NM_004428 Hs 1624 ephπn-A1 239
428505 AL035461 Hε 2281 chromogranm B (sxretograπin 1) 32790
444783 AK001468 Hε 62180 anillin (Drosophila Scraps homolog), act 9050
445593 AW203963 Hε 150896 ESTs 4920
450701 H39960 Hs 288467 Homo sapiens cDNA FLJ12280 fis, clone MA 312
424420 BE614743 Hs 146688 prostaglandin E synthase 1 93
408660 AA525775 Hs 292523 ESTs, Moderately similar to PC4259 fern 3990
417940 R28205 Hs 24230 ESTs 5720
434206 AW136973 Hs 288516 ESTs, Weakly similar to S69890 mitogen i 251
439920 H05430 Hs 288433 neurotπmin 1 91
432542 AW083920 Hs 16098 claudin 2 347 410418 D31382 Hs 63325 transmembrane protease serine 4 382
415989 AI267700 Hs 317584 ESTs 18250
414987 AA524394 Hs 294022 hypothetical protein FLJ14950 284
400024 AFFX control - HUMRGE/M10098.5 482
418067 AI127958 Hs 83393 cyεtatiπ E/M 4 19
424687 J05070 Hs 151738 matnx metalloproteinase 9 (gelatmase B 292
405909 NA Target Exon 71 80
448811 AI590371 Hs 174759 ESTs 674
430044 AA464510 Hs 152812 ESTs 1491
406690 M29540 Hs 220529 carcmoembryonie antigen related cell ad 757 80
418245 AA088767 Hs 83883 transmembrane prostate androgen induced 1 65
423733 AA330281 gb EST33985 Embryo, 12 week II Homo sapi 10470
450154 R15891 Hs 281587 Human (clone CTG-A4) mRNA sequence 14300
422487 AJ010901 Hs 198267 mucin 4 tracheobronchial 311 80
424902 NM 003866 Hs 153687 mositol polyphosphate 4-phosphatase, ty 6300
422330 D30783 Hs 115263 epiregul 141 70
436749 AA584890 Hs 5302 Ixtin galactoside binding, soluble, 4 259
423634 AW959908 Hs 1690 hepaπn binding growth factor binding pr 181 90
430691 C14187 Hs 103538 ESTs 9580
401682 NA Target Exon 6 17
422440 NM 004812 Hs 116724 aldo-keto reductase family 1 , member B10 31860
431441 U81961 Hs 2794 sodium channel nonvoltage-gated 1 alpha 251
442560 AA365042 Hs228598 ESTs, Weakly similar to 2004399A chromos 390
414812 X72755 Hs 77367 monokine induced by gamma interferon 43460
425211 M18667 Hs 1867 progastπcsin (pepsinogen C) 658
421430 AW207555 Hs 97093 Homo sapiens cDNA FLJ23004 fis clone L 35 10
419693 AA133749 Hs 301350 FXYD domain-containing ion transport reg 245
409420 Z15008 Hs 54451 laminin, gamma 2 (nicem (100kD), kalmi 856
448437 AW470125 gb xw60c04 x1 NCI.CGAP.Pan1 Homo sapiens 7980
406671 AA129547 Hs 285754 met proto-oncogene (hepatocyte growth fa 14730
411558 AA102670 Hs70725 gamma aminobutyπc xid (GABA) A rxepto 3007
424586 NM 003401 Hs 150930 X ray repair complementing def∞tive rep 55 10
428227 AA321649 Hs2248 small inducible cytokine subfamily B (CX 40520
438746 AI885815 Hs 184727 ESTs 357
456032 AW957446 Hε301711 ESTs 13680
431808 M30703 Hs 270833 amphiregulm (schwannoma-deπved growth 36 10
423472 AF041260 Hs 129057 breast carcinoma amplified sequence 1 993
439759 AL359055 Hs 67709 Homo εapiens mRNA full length insert cDN 14640
442295 AI827248 Hs224398 Homo εapieπs cDNA FLJ11469 fis, clone HE 2060
428928 BE409838 Hs 194657 cadhenn 1, type 1, E-cadhenn (epitheli 1 58
437157 BE048860 Hs 120655 ESTs 91 80
404285 NA C6001909 gι|704441|dbj|BAA18909 1| (D298 12380
424036 AA770688 Hε28777 H2A hiεtoπe family, member L 526
422026 U80736 Hs 110826 tπnucleotide repeat containing 9 13040
428664 AK001666 Hs 189095 similar to SALL1 (sal (Drosophila) like 4880
437935 AW939591 Hs5940 mucin 13, epithelial transmembrane 3 15
423575 C18863 Hs163443 Homo sapienε cDNA FLJ 11576 fis, clone HE 25320
422956 BE545072 Hs 122579 hypothetical protein FLJ10461 8000
406722 H27498 Hs 293441 Homo sapiens SNC73 protein (SNC73) mRNA, 305
413278 BE563085 Hs833 interferon stimulated protein, 15 kDa 1 66
439750 AL359053 Hε57664 Homo sapiens mRNA full length insert cDN 2302
434377 AW137148 Hε 306593 Homo sapiens cDNA FLJ11382 fis, clone HE 78 10
425428 AL110261 Hε 157211 DKFZP586B0621 protein 1 74
421298 AW172431 Hs 13012 ESTs 133 10
422424 AI186431 Hs296638 prostate differentiation fxtor 265
421582 AI910275 Hs 1406 trefoil factor 1 (pS2) 5 17
401480 NA Target Exon 7370
409269 AA576953 Hs 22972 hypothetical protein FLJ13352 13770
409757 NM.001898 Hs 123114 cystatin SN 936
449722 BE280074 Hε 23960 cyclin B1 16270
452240 AI591147 Hs 61232 ESTs 151 90
415165 AW887604 Hs 78065 complement component 7 285
423673 BE003054 Hs 1695 matnx metalloproteinaεe 12 (mxrophage 29030
428450 NM 014791 Hs 184339 KIAA0175 gene product 689
409041 AB033025 Hs 50081 KIAA1199 protein 334 10
453331 AI240665 Hs8895 ESTε 1285
400288 X06256 Hs 149609 integπn, alpha 5 (fibronxtin rxeptor, 1242
453160 AI263307 Hs 239884 H2B histone family, member L 15640
444015 AI472865 Hs 135534 ESTε 1460
421308 AA687322 Hs 192843 leucine zipper protein FKSG14 8720
448045 AJ297436 Hs20166 proεtate εtem cell antigen 52620
422426 W79117 Hs 58559 ESTε 58 30
450737 AW007152 Hs 203330 ESTε 281 00
429504 X99133 Hs 204238 lipxalm 2 (oncogene 24p3) 31 25
456553 AA721325 Hs 189058 ESTε, Highly similar to Similar to a C e 7800
413281 AA861271 Hs 222024 transcnption fxtor BMAL2 212 10
417866 AW067903 Hs 82772 collagen, type XI, alpha 1 340
431630 NM 002204 Hs 265829 integπn, alpha 3 (antigen CD49C alpha 348
400298 AA032279 Hs61635 six transmembrane epithelial antigen of 281 50
431753 X76029 Hs 2841 neuromedin U 6050
428651 AF196478 Hs 188401 annexm A10 50830
424905 NM 002497 Hε 153704 NIMA (never in mitosis gene a) related k 8580
433132 AB026264 Hε 284245 hypothetical protein IMPACT 5530 435039 AW043921 Hs 130526 ESTs 6400
447033 AI357412 Hs 157601 ESTs 12320
433578 BE336886 Hs 3416 adipose differentiation related protein 922
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 52570
411274 NM 002776 Hs 69423 kallikrein 10 (KLK10) (PRSSL1) (nesl) 4436
452705 H49805 Hs 246005 ESTs 120 10
428479 Y00272 Hs 184572 cell diviεion cycle 2, G1 to S and G2 to 9230
425397 J04088 Hs 156346 topoisomerase (DNA) II alpha (170kD) 29 37
422562 AI962060 Hs 118397 AE binding protein 1 384
428579 NM 005756 Hs 184942 G protein-coupled receptor 64 2780
428242 H55709 Hs 2250 leukemia inhibitory factor (cholmergic 409
440868 R79707 Hs 263339 ESTs, Moderately similar to I38022 hypot 76 30
421493 BE300341 Hs 104925 xtoder al neural cortex (with BTB-like 237
410199 AW377424 Hs 205126 Homo sapiens cDNA FLJ22667 fis, clone H 344
426320 W47595 Hs 169300 transforming growth factor, beta 2 13810
419290 AI128114 Hs 112885 εpinal cord-derived growth factor-B 345
459309 AA040620 Hs 5672 hypothetical protein AF140225 12780
415138 C18356 Hs 295944 tissue factor pathway inhibitor 2 361 20
422553 AI697720 Hs 171455 ESTs, Weakly similar to T31613 hypotheti 13660
432375 BE536069 Hs 2962 S100 calcium binding protein P 6 87
400534 #(NOCAT) C22000015 gι|12741327|ref|XP_0088332| z 8900
428970 BE276891 Hs 194691 retinoic acid induced 3 478
423739 AA398155 Hε 97600 ESTs 13560
450375 AA009647 Hε 8850 a disintegnn and metalloprotemase doma 14850
423554 M90516 Hs 1674 glutamine fructose-6-phosphate transamiπ 8770
407001 U12471 Hs 247954 Human thrombospondιn-1 gene, partial eds 7680
419261 X07876 Hs 89791 winglesε-type MMTV integration site fami 11060
419948 AB041035 Hs 93847 NM.016931 Homo sapiens NADPH oxidase 4 ( 23460
428471 X57348 Hs 184510 stratifin 372
427051 BE178110 Hs 173374 Homo sapiens cDNA FLJ10500 fis, clone NT 437 90
425234 AW152225 Hs 165909 ESTs, Weakly similar to I38022 hypotheti 219 20
419842 AA765489 Hs 104350 ESTs 3 80
418007 M13509 Hs 83169 matrix metalloprotemase 1 (MMP1, inters 60680
444207 AI565004 Hs 79572 cathepsin D (lysoεomal aεpartyl protease 262
442432 BE093589 Hs 38178 hypothetical protein FLJ23468 25870
413753 U17760 Hs 75517 laminin, beta 3 (nicem (125kD), kalmin 30480
441384 AA447849 Hs 288660 Homo sapiens cDNA FLJ22182 fis, clone H 878
418327 U70370 Hs 84136 paired like homeodomain transcnption fa 1095
452401 NM 007115 Hs 29352 tumor nxrosis fxtor, alpha-induced pro 19970
438199 AW016531 Hs 122147 ESTs 6770
422420 U03398 Hs 1524 tumor necrosis factor (ligand) superfami 107 20
431183 NM 006855 Hs 250696 KDEL (Lys Asp Glu-Leu) endoplasmic retic 359
417389 BE260964 Hs 82045 midkine (neuπte growth-promoting fxtor 345
421937 AI878857 Hs 109706 hematological and neurological expressed 3 17
427961 AW293165 Hs 143134 ESTs 10930
422043 AL133649 Hs 110953 retinoic acid induced 1 298
426711 AA383471 Hε 180669 conserved gene amplified in osteosarcoma 27650
450983 AA305384 Hs 25740 ER01 (S cerevιsιae)-lιke 5 28
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of 27 85
433001 AF217513 Hs 279905 clone HQ0310 PRO0310p1 34230
424086 A1351010 Hs 102267 lysyl oxidase 21350
432731 R31178 Hs 287820 fibronxtin 1 185 10
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient, yeast h 106 10
414085 AA114016 Hs 75746 aldehyde dehydrogenase 1 family, member 227
417308 H60720 Hs 81892 KIAA0101 gene product 405 30
438146 Z36842 Hs 57548 ESTs 838
424800 AL035588 Hs 153203 MyoD family inhibitor 172 10
416143 AI955650 Hs 79033 gluta inyl-peptide cyclotransferase (glu 4570
408380 AF123050 Hs 44532 diubiquitin 11 18
412140 AA219691 Hs 73625 RAB6 interxting, kinesm like (rabkmes 149 10
422963 M79141 Hs 13234 ESTs 3360
409956 AW103364 Hs 727 inhibin, beta A (xtivm A, xtivm AB a 673
407756 AA116021 Hs 38260 ubiquitin spxific protease 18 896
424897 D63216 Hs 153684 fnzzled-related protein 31240
421110 AJ250717 Hs 1355 cathepsin E 79080
411789 AF245505 Hs 72157 DKFZP564I1922 protein 3 17
421485 AA243499 Hs 104800 hypothetical protein FU10134 852
409632 W74001 Hs 55279 seπne (or cysteine) proteinaεe inhibito 55800
406837 R70292 Hs 156110 immunoglobulin kappa constant 436
426440 BE382756 Hs 169902 solute earner family 2 (facilitated glu 283
421470 R27496 Hs 1378 annexm A3 24290
407242 M18728 gb Human nonspecific crossrexting antig 3691
432101 AI918950 Hs 123642 EphA3 221 60
406687 M31126 Hs 272620 matrix metalloprotemase 11 (MMP11 , stro 534
429170 NM.001394 Hs 2359 dual spxificity phosphatase 4 29200
408308 AL033377 Hs 44197 hypothetical protein DKFZp564D0462 18490
435202 AI971313 Hs 170204 KIAA0551 protein 6480
407216 N91773 Hs 102267 lysyl oxidase 7370
409231 AA446644 Hs 692 GA733-2 antigen, epithelial glycoprotein 320
407881 AW072003 Hs 40968 heparan sulfate (glucosamine) 3-0 sulfot 28870
407811 AW190902 Hs 40098 cysteine knot superfamily 1, BMP antagon 502 60
420899 NM.001628 I Hs 100194 arachidonate 5-lιpoxygenase-actιvatιπg p 613
441020 W79283 Hs 35962 ESTs 178 90 453857 AL080235 Hs 35861 DKFZP586E1621 protein 50430
428966 AF059214 Hs 194687 cholesterol 25 hydroxylase 242 10
413435 X51405 Hs 75360 carboxypeptidase E 730
436476 AA326108 Hs 33829 bHLH protein DEC2 24720
406747 AI925153 Hs 217493 annexm A2 11000
455800 R22479 Hs 167073 Homo sapienε cDNA FLJ13047 fiε, clone NT 112 10
431211 M86849 Hs 323733 gap junction protein, beta 2, 26kD (conn 58390
431890 X17033 Hs 271986 integnn, alpha 2 (CD49B alpha 2 εubuni 656
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (placenta 46090
444665 BE613126 Hs 47783 B aggreεεive lymphoma gene 20440
437763 AA469369 Hs 5831 tissue inhibitor of metalloproteinase 1 775
418870 AF147204 Hs 89414 chemokine (C-X-C motif), rxeptor 4 (fus 1461
424560 AA158727 Hs 150555 protein predicted by clone 23733 9980
436396 AI683487 Hs 152213 wingless type MMTV integration site farm 24220
407137 T97307 gb ye53h05 s1 Soareε fetal liver εpleen 1788
410668 BE379794 Hs 65403 hypothetical protein 418
427660 A1741320 Hs 114121 Homo εapiens cDNA FLJ23228 fis, clone C 11640
408826 AF216077 Hs 48376 Homo sapienε clone HB 2 mRNA sequence 60 30
442577 AA292998 Hs 163900 ESTε 418
416498 U33632 Hs 79351 potassium channel, subfamily K, member 1 33420
447343 AA256641 Hs 236894 ESTs Highly similar to S02392 alpha 2-m 8 16
451277 AK001123 Hs 26176 hypothetical protein FLJ10261 37530
445133 AW157646 Hs 153506 ESTs 29240
414799 AI752416 Hs 77326 insulin like growth factor binding prote 438
431806 AF186114 Hs 270737 tumor necrosis fxtor (ligand) superfami 8900
437330 AL353944 Hs 50115 Homo sapiens mRNA, cDNA DKFZp761J1112 (f 322 10
410687 U24389 Hs 65436 lysyl oxidase like 1 9 10
417409 BE272506 Hs 82109 εyndecaπ 1 405
426471 M22440 Hs 170009 transforming growth factor, alpha 138 60
458809 AW972512 Hs 20985 sιn3-aεsxιated polypeptide, 30kD 25050
448625 AW970786 Hs 178470 hypothetical protein FLJ22662 489
450506 NM 004460 Hs 418 fibroblast activation protein, alpha 11 76
433336 AF017986 Hs 31386 sxreted fnzzled-related protein 2 479
408491 AI088063 Hs 7882 ESTs 825
437802 AI475995 Hs 122910 ESTs 4 54
408296 AL117452 Hs 44155 DKFZP586G1517 protein 175 10
421155 H87879 Hs 102267 lyεyl oxidase 170 10
451310 AW250651 Hs 26213 Human DNA sequence from clone RP3-447F3 291
439867 AA847510 Hs 161292 ESTs 261 60
417771 AA804698 Hs 82547 retinoic xid rxeptor responder (tazaro 72300
410763 AF279145 Hs 8966 hypothetical protein FLJ21776 251 70
431385 BE178536 Hs 11090 membrane-spanning 4-domaιns, subfamily A 15550
457180 R26022 Hs 194662 calponm 3, acidic 6800
424408 AI754813 Hs 146428 collagen, type V, alpha 1 17 19
452679 Z42387 Hs 83883 tranεmembrane, prostate androgen induced 5 32
425139 AW630488 Hs 325820 protease, seπne, 23 371 90
432978 AF126743 Hs 279884 DNAJ domain-containing 727
406850 AI624300 Hs 172928 collagen, type I, alpha 1 1930
421991 NM 014918 Hs 110488 KIAA0990 protein 19050
421814 L12350 Hs 108623 thrombospondm 2 1502
409703 NM_006187 Hs 56009 2'-5'-olιgoadenylate synthetase 3 (100 k 28 57
452281 T93500 Hs 28792 Homo sapiens cDNA FLJ11041 fis, clone PL 51920
413048 M93221 Hs 75182 mannose rxeptor, C type 1 24060
404210 #(NOCAT) NM 005936 Homo εapienε myeloid/lymphoid 40460
452862 AW378065 Hs 8687 ESTε 36420
447072 D61594 Hs 17279 tyrosylprotein sulfotransferase 1 22620
426935 NM 000088 Hs 172928 collagen, type I, alpha 1 431
427390 AI432163 Hs 268231 Homo sapiens cDNA FLJ23111 fis, clone L 1041
417259 AW903838 Hs 81800 chondroitin sulfate protxglycan 2 (vers 2246
451295 AI557212 Hs 17132 ESTε, Moderately similar to 154374 gene 2374
448569 BE382657 Hs 21486 signal transducer and activator of tranε 568
417148 AA359896 Hs 293885 hypothetical protein FLJ 14902 19080
432359 AA076049 Hs 274415 Homo εapiens cDNA FLJ10229 fis, clone HE 23050
422278 AF072873 Hs 114218 fπzzled (Drosophila) homolog 6 361 90
422545 X02761 Hs 287820 fibronxt 1 881
442379 NM 004613 Hs 8265 transglutaminase 2 (C polypeptide, prote 730
417412 X16896 Hε 82112 interieukin 1 receptor, hype 1 26720
422110 AI376736 Hs 111779 sxreted protein, xidic, cysteine πch 507
431512 BE270734 Hs 2795 lactate dehydrogenase A 270 10
417433 BE270266 Hs 82128 5T4 oncofetal trophoblast glycoprotein 50460
426369 AF134157 Hs 169487 Kreisler (mouεe) maf-related leucine zip 1062
437470 AL390147 Hs 134742 hypothetical protein DKFZp547D065 2 80
417944 AU077196 Hε 82985 collagen, type V, alpha 2 1401
428797 AA496205 Hε 193700 Homo εapiens mRNA, cDNA DKFZp586l0324 (f 9 15
434423 NM 006769 Hε 3844 LIM domain only 4 29730
426125 X87241 Hε 166994 FAT tumor suppreεεor (Drosophila) homolo 486 20
422573 AW297985 Hε 295726 integπn, alpha V (vitronxtin rxeptor 973
421552 AF026692 Hs 105700 sxreted fπzzled related protein 4 76290
424730 NM 003358 Hε 23703 ESTs, Moderately similar to CEGT.HUMAN C 781
400133 NA Eoε Control 357 00
444381 BE387335 Hε 283713 ESTs, Weakly similar to S64054 hypotheti 115030
422048 NM 012445 Hs 288126 spondin 2, extracellular matrix protein 4 50
446019 AI362520 Hs 279789 hiεtone deacetylaεe 3 11 26 426490 NMJXJ1621 Hs 170087 aryl hydrocarbon receptor 45950
422687 AW068823 Hs 119206 insulin like growth factor binding prote 2 68
432401 NM 013330 Hs 274479 NME7 499
437223 C15105 Hs 330716 Homo sapiens cDNA FLJ14368 fis, clone HE 7 65
Table 41 B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT Number Accessions
416913 163001 1 AW934714 BE161007 BE162500 AW749902 AW749864 BE162498 BE161005 AA190449 AW513465 BE161006 BE162499
419570 1860604 1 W68738 W68831
423733 231476 1 AA330281 0AA330232 AW962521
434665 390530 1 AA642125 AA654516
448437 763310.1 AW470125 AI734872 AI749559 AW856504 AI583942 AW779036 AW843429 AW844876 AI520713 AW847236
Table 41 C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham 1 et al * refers to the publication entitled "The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489 495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400534 6981826 Minus 278637-279292
400560 9843598 Plus 94182-9432397056-97243,101095 101236,102824-103005
400836 8954179 Plus 677-1188
401201 9743387 Minus 138534-138629,139234-139294,140121-140335,142033-142479
401480 7321503 Plus 166120-166347,166451-166557,169651-169832
401541 8072607 Minus 50018-50158
401682 4755167 Plus 13022-13473
401732 1200312 Plus 19346-19525,19625-19708,19897-19973,20067-20130,20215-20414
403207 7630829 Plus 89914-90033,90729-90855,91131-91198
403574 8101156 Plus 5542-6176
403776 7770611 Minus 1414-1513,1624-1756
404142 9856692 Minus 80316-80459
404210 5006246 Plus 169926-170121
404285 2326514 Pluε 32282-32416
404286 2326514 Pluε 51086-51301
404287 2326514 Plus 53134-53281
404682 9797231 Minus 40977-41150
404866 9366919 Minus 11743-11929
405281 6139075 Minus 34202-34351,35194-35336,45412-45475,4573145958,47296-47457,4954949658,4979049904,50231-50342,53583-53667,54111-54279
405849 7651817 Minus 17705-18287
405909 7705180 Minus 86985-87233
406173 7230224 Plus 12925-13213
406293 5686274 Minus 17646-17953
406319 9211730 Minus 82320-82561
406399 9256288 Minus 63448-63554
TABLE 42A 574 genes upregulated in pancreatic cancer relative to normal body tissues
Tabte 42A lists about 574 genes upregulated in pancreatic cancer relative to normal body tissues that are likely to encode proteins amenable to modulation by small olxuleε peptideε, or antibodies These genes were selected from 59680 probesets on the Eos/Affymetnx Hu03 Genechip array Gene expression data for exh probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative level of mRNA expreεsion The protein products of these geneε often contain one or more domainε indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death-domain, 7tm, phosphatase, or lon.transporter) Certain predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar xcession number, GenBank xcession number
UniGenelD UniGene number Pred Prot Domains Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain other protein domain abbreviabons are from PFAM (Nucleic Acids Research, 2002, 30276-280)
UniGene Title UniGene gene title
R1 90th percentile of pancreatic cancer Als divided by the 50th percentile of normal tissue Als
R2 90th percentile of pancreatic cancer Als divided by the 90th percentile of normal pancreas Als, where the 15th percentile of all normal tissue Als was εubtrxted from both the numerator and denominator
Pkey, ExAccn, UnigenelD, Unigene Title, Pred Prot Domains, R1, R2
426230, AA367019, Hs 241395, proteaεe, seπne, 1 (trypsin 1), trypsιn,toxιn_4,SS=M, 10729, 1 07 415934, NM.000928, Hs 992, phospholipase A2, group IB (pancreas), phoslιp,SS=M, 8367, 1 06
421996, AW583807, Hs 1460, glucagon, hormone2,SS=M, 5935, 1 61 406399, , , NMJ03122* Homo sapiens serine protease , kazal,SS=M 5549, 1 08 444381, BE387335, Hs 283713, hypothetical protein BC014245, Collagen,TM=M SS=M, 5365, 4361 406685, M18728, , gb Human nonspecific crossreacting antig, ιg,TM=M,SS=M, 5273, 2283 428698, AA852773, Hs 334838, KIAA1866 protein, none.NA NA, 3244, 13 11 437145, AF007216 Hs 5462, solute earner family 4, sodium bicarboπ, HC03_cotranεp,TM=Y„ 29 80, 1 46 428874, W32133, Hs 194366, transthyretm (prealbumm, amyloidosis t, Transthyretιn,SS=M, 2942, 1 94 444754, T83911, Hs 374341, transmembrane 4 superfamily member 4, none,TM=Y,SS=M, 2878, 3 13
418068, AW971155, Hs 293902, ESTs, Weakly similar to ISHUSS protein d, none,TM=M,SS=M, 28 61 , 098 438091 , AW373062, Hs 351546, nuclear receptor subfamily 1 , group I, m, hormone.rec.zf C4,none, 2538, 363 413719, BE439580, Hs 75498, small inducible cytokine subfamily A (Cy, IL8,SS=M, 2464, 721 417771, AA804698, Hε 82547, retinoic xid receptor responder (tazaro, none.none, 2377, 674 414998, NM.002543, Hs 77729, oxidised low density lipoprotem (Ixtin, lectιn_c,TM=Y,SS=M 2296, 457
418318, U47732, Hs 84072, transmembrane 4 superfamily member 3, transmembrane4,TM=Y,SS=M, 2231 , 542 425573, AB006423, Hs 158308, serine (or cysteine) proteinase inhibito, serpιπ,GCV_H TM=M,SS=M, 21 91, 1 03 433110, D56494, Hs 3191, rat regenerating lεlet-deπved-like, hum, lectιn_c,TM=M,SS=M, 21 90 060 426490, NM.001621, Hε 170087, aryl hydrocarbon rxeptor, PAC,PAS,TM-M„ 21 41, 1989 453863, X02544, Hs 572, orosomucoid 1, lipxalin aldedh,ubιquιtιn,IRK,SS=M, 2080, 8 12
421126, M74587, Hε 102122 insulin like growth factor binding prote, thyroglobulinj ,IGFBP,SS=Y, 2060, 848 451035, AU076785, Hs 430, plastm 1 (I lεoform), efhand,CH,Adaptιπ_N,SS=M, 1925 353 413859, AW992356, Hs 8364, Homo sapienε pyruvate dehydrogenase kina SAM_PNT,πone, 18 38, 253 420332, NM.001756, Hs 1305, serine (or cysteine) proteinase inhibito, serpιn,TM=M,SS=M, 18 19, 229 438089, W05391 , Hε 351546, nuclear rxeptor subfamily 1 , group I, , hormone.rec.zf C4,none, 17 67, 480
417426, NM.002291, Hs 82124, laminin, beta 1, lamιnιn_EGF,lamιnιn_Nterm,ιntegπn B,SS=M, 1708, 637 427509, M62505, Hs 2161, complement component 5 rxeptor 1 (C5a 1, 7tm.1,TM=Y,SS=M, 16 89, 7 15 441031, AI110684, Hs 7645, fibrinogen, B beta polypeptide, fibπnogen_C,G-alpha,arf,TM=M SS=M, 1659, 7 74 445033, AV652402, Hs 72901 , cyclm-dependent kinase inhibitor 2B (p1 , ank,, 1628, 922 431183, NM.006855, Hs 250696, KDEL (Lys-Asp Glu Leu) endoplasmic retic, ER.Iumen.rxept TM=M,SS=M, 1596, 238
444784, D12485, Hs 11951, xtonudeotide pyrophosphatase/phosphodi, Somatomedιn_B,Endonuclease,Phosphodιeεt,TM=Y,SS=M, 1565, 1 33 408243, Y00787, Hε 624, interieukin 8, HLH,PAS,IL8,TM=M„ 1553 434 419355, AA428520, Hε 90061, progesterone binding protein, herne.1 ,TM=Y,SS=M, 1545, 10 50 426006 R49031, Hs 22627, ESTs, pkinase.TBC, 15 17, 058 433376, AI249361, Hs 74122, caspase 4, apoptosis-related cysteine pr, CARD,ICE_p10,ICE_p20,SS=M, 1484, 304
422260, AA315993 Hs 105484, regenerating gene type IV, lxtιn_c,SS=M, 1471, 289 430280, AA361258, Hs 237868, interieukin 7 receptor, fn3,none, 1428, 11 47
408983, NM 000492, Hε 663, cystic fibrosis transmembrane conductanc, ABCJran ABC_membrane,PRK,Bac_export_3,TM=Y„ 1398, 1 18 414812, X72755, Hs 77367, monokine induced by gamma interferon, IL8,TM=M,SS=Y, 1381, 7 69 429170, NM_001394 Hε 2359, dual spxificity phosphatase 4, Rhodanese,DSPc,Y_phosphatase Rιbosomal_S3_N,TM=M„ 1359, 224
425988, BE045897, Hs 53985, ESTs, Weakly similarto I38022 hypotheti, none.none, 1354, 095 409512, AW979187 Hs 293591, melanoma differentiation assxiated prot, DEAD.helicase C,CARD,TM=M„ 1348, 359 429556, AW139399, Hs 98988, ESTs, πoπe,TM=M„ 1320, 1 16 417079, U65590, Hs 81134, interleukin 1 receptor antagonist, IL1,SS=M, 1283, 772 427286, AW732802 Hs 2132, epidermal growth factor rxeptor pathway, SH3,TonB_boxC,TM=M„ 1272, 901
431912, AI660552, Hs 356183, ESTs, Weakly similarto A56154 Abl subεt, none,Acyl-CoA_dh,Aoyl-CoA dh M Acyl CoA.dh N, 1272, 672 412116, AW402166, Hs 784, Epstein Barr virus induced gene 2 (lymph, 7tm 1,TM=Y,SS=M, 1271, 1256 425397, J04088, Hs 156346, topoisomerase (DNA) II alpha (170kD), DNA_gyraseB,DNA_topoιsolV,HATPase_c,SS=M, 1252, 492 409142, AL136877, Hs 50758, SMC4 (structural maintenance of chromoso, ABC_tran,M,SMC_N,SMC_C,DUF164,πone, 1238, 7 59 428157, AI738719, Hs 198427, hexokmase 2, hexokιnase,hexokιnase2,none, 1234, 11 53
424273, W40460, Hs 144442, phospholipase A2, group X, phoslιp,TM=M,SS=Y, 1232, 302 414821, M63835, Hε 77424, Fc fragment of IgG high affinity la, re, ιg,TM=Y,SS=M, 1229, 221 415323, BE269352, Hε 949, neutrophil cytosolic factor 2 (65kD, chπ SH3,TPR,TM=M„ 12 16, 4 14
427283, AL119796, Hs 174185, xtonudeotide pyrophosphatase/phosphodi, Sulfatase.Somatomedm B,Phosphodιest,Endonuclease,TM=M,SS=Y, 11 97, 593 434779, AF153815, Hs 50151, potassium inwardly rxtifymg channel, s, IRK,TM=Y„ 11 76, 1 58
426227, U67058, Hs 154299, Human proteinase activated receptor-2 R, 7tm 1,TM=Y,SS=M, 11 75, 356 412228, AW503785, Hs 73792, complement component (3d/Epsteιn Barr vi, suεhι,TM=Y,SS=M, 11 67, 377 450737, AW007152, Hε 63325, transmembrane protease, senne 4, trypsinjdl rxepLa none, 11 65, 452
439750, AL359053, Hs 57664, Homo sapiens mRNA full length insert cDN, IMPDH CIMPDH N,CBS,ιntegπn B.Ricin B Ixtin, 11 56, 546 431512, BE270734, Hs 2795, lactate dehydrogenase A, ldh,ldh_C,SH3,pkιnase,UBA,TM=M , 11 55, 511
429638, AI916662, Hs 211577, kinxtin 1 (kinesm rxeptor), bZIP,Tropomyosιn,spxtrιn,LBP BPI CETP,B56,M,TM=Y,SS=M, 11 47, 465 445133, AW157646, Hs 198689, ESTs, efhand,spxtπn,GAS2,SH3,Plxtιn,RA,Xylosejsom,FlιD,bZIP,Tropomyosιn,Myc-LZ,M,ldh_C,CH,AIP3,TM=M„ 11 41, 1262 411352, NM_002890, Hs 758, RAS p21 protein xtivator (GTPase xtiva, SH2,SH3,C2,PH,RasGAP,TM=M,SS=M, 11 24, 995 447343, AA256641, Hs 236894, ESTs, Highly similar to S02392 alpha-2-m, none.none, 11 19, 4 16 422616, BE300330, Hs 118725, selenophoεphate εynthetaεe 2„AIRS,AIRS_C,TM=M„ 11 17, 598
422241, Y00062, Hs 170121, protein tyrosine phosphatase, rxeptor t, kιnesιn,fn3,Y_phosphatase,TM=M„ 11 14, 909 440594, AW445167, Hε 126036, ESTε, none.none, 11 05, 1645
425289, AW139342, Hs 155530, interferon, gamma-iπducible protein 16, PAAD DAPIN,HIN,SS=M, 11 05, 1038 427700, AA262294, Hs 180383, dual spxificity phosphatase 6, Rhodanese,DSPc,TM=M„ 11 05, 470 448811, AI590371, Hε 199460, ESTε, none,TM=Y„ 1085, 969
424321, W74048, Hs 1765, lymphxyte-spxific protein tyrosine km, SH2,SH3,pkιπase,TM=M„ 1072, 865 429083, Y09397, Hs 227817, BCL2-related protein A1, Bcl-2,TM=M„ 1051, 1297
424247, X14008, Hs 234734, lysozyme (renal amyloidosiε), lys,ιg,FAD_Synth,ldh,ldh C,pkιnaεe,SS=M, 10 37, 635 436856, AI469355, Hε 127310, ESTs, pkιnase,rrm,TM=M„ 1036, 274 427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lllb, π ιg,TM=Y,SS=M, 1034, 3 14
417018, M16038, Hs 80887, v-yes-1 Yamaguchi sarcoma viral related , SH2,SH3,pkmase,TM=M„ 1034, 447 418299, AA279530, Hε 83968, integnn, beta 2 (antigen CD18 (p95), ly, ιntegπn_B,EGF,PSI,TM=Y,SS=M, 1021, 458 451820, AW058357, Hs 199248, ESTs, 7tm_1,TM=Y,SS=M, 10 18, 267
413048, M93221, Hs 75182, mannose receptor, C type 1, fn2,lxtιn_c,Rιcιn_B lxtιn,Xlιnk,TM=Y,SS=M, 10 17, 835 429752, H52348, Hs 36636, ESTs, pkmase.pk ase, 10 13, 1235
452721, AJ269529, Hs 301871, solute camerfamily 37 (glycerol-3 pho, MORN,sugar_tr,TM=Y,SS=M, 1008, 874 421462, AF016495 Hε 104624, aquapoπn 9, MIP,TM=Y,SS=M, 1005, 606 452698, NM.001295, Hs 301921, chemokine (C-C motif) rxeptor 1, 7tm 1,TM=Y,SS=M, 998, 3 16 416389, AA180072, Hs 149846, integπn, beta 5, integπn.B.none, 985, 959 421044, AF061871, Hs 101302, Human DNA εequence from clone RP1-238D15, fn3,vwa,Collagen,TSPN,TM=M,SS=M, 978, 596
446620, AA128808, Hs 179902, transporter like protein, none,TM=Y,SS=M, 975, 264 405102, , , C15001220* gι|4469558|gb|AAD21311 1| (AF, DAG PE-bιnd,PH,RhoGEF,DC1,SS=M, 974, 1 88 418693, AI750878, Hs 87409, thrombospondm 1, EGF,tsp_1,vwc,TSPN,tsp_3,SS=M, 972, 694 426535, AU077012, Hs 288582, ESTs, Weakly similar to ubiquitous TPR m, Kuπιtz_BPTI,Kunιtz_BPTI,7tm_2,HRM, 968, 1058 448105, AW591433, Hs 298241 , Transmembrane protease, serine 3, Idl.rxept a.trypεin TM=Y,SS=M, 967, 406 456266, L29073, Hε 198726, cold εhxk domain protein A, 7tm_2,HRM,CSD,TM=Y,SS=M, 962, 236 410240, AL157424, Hs 61289, synaptojamn 2, Exo_eπdo_phoε,Syja_N,rrm Gram ve_poπns TM=M„ 9 62, 377 457001 , J03258, Hs 2062, vitamin D (1 ,25- dihydroxyvitamin D3) re, hormone_rec,zf-C4,Mela!lothιo_5,TM=M„ 960, 805
456373, BE247706, Hs 89751, membrane spanning 4-domams, subfamily A, none,TM=Y„ 9 57, 377 416847, L43821, Hs 80261, enhancer of filamentation 1 (caε like do, SH3,TM=M , 956, 1050 437158, AW090198 Hs 348709, KIAA1150 protein, none NA NA, 955, 887 426108, AA622037, Hε 166468, programmed cell death 5, DUF122,TM=M„ 947, 567 403344, , , NM_000341 Homo εapiens solute earner fa, alpha amylase,TM=Y„ 947, 1 42
449543, AF070632, Hs 23729, Homo εapiens clone 24405 mRNA sequence K_tetra,ιon_trans,none, 946, 3 12 433233, AB040927, Hs 301804, KIAA1494 protein, SH3 zf-C3HC4,TM=M„ 942, 401 444838, AV651680, Hs 208558, ESTs, ιntegπn_A,FG-GAP,none, 942, 1 87 439803, AA001021, Hs 6685, thyroid hormone rxeptor interactor 8, none.none, 941, 555 428505, AL035461, Hs 2281, chromogranm B (seoretograπin 1), Granin SS=M 940, 346
411213, AA676939, Hs 69285, neuropilm 1 , MAM.F5 Fβ.type C CUB,CUB,MAM,F5_F8_type_C, 938, 632 432810, AA863400, Hs 374489, ESTs, none,Skp1,AAA 938, 436 427581, NM_014788 Hs 179703, KIAA0129 gene product, SPRY,zf-B_box TM=M„ 934, 826 413109, AW389845, Hs 110855, ESTs, similar to leukemia viruε rxeptor, PH04,πoπe, 934, 467 428450, NM_014791, Hs 184339, KIAA0175 gene product, KA1,pkιnase,TM=M„ 9 31, 4 24
408113, T82427, Hε 194101 , Homo εapieπs cDNA FLJ20869 fis, clone A, 7tm_3,πone, 924, 7 12 448030, N30714, Hs 325960, membrane-spanning 4-domaιns subfamily A, πone,TM=Y,SS=M, 9 23, 603 437672, AW748265, Hs 5741, flavohemoprotem b5', heme_1,NAD_bιndιng lιpoxygenase,FAD_bιndιng_6,TM=M„ 922, 1072 416498, U33632, Hs 79351, potassium channel, subfamily K, member 1, ion trans,TM=Y,SS=M, 920, 446 409956, AW103364, Hε 727, inhibin, beta A (activin A, activin AB a, TGF-beta,TGFb_propeptιde,Tub,SS=M, 9 19, 1646
413095, AA494359, Hs 30715, potassium voltage-gated channel, Isk rel, none START, 9 15, 2 18 418838, AW385224, Hε 35198, xtonudeotide pyrophosphatase/phosphodi, Phosphodιest,TM=Y,SS=M, 9 14, 303 452960, AK001335, Hε 31137, protein tyroεine phoεphatase, rxeptor t, Y_phosphatase,none, 9 14, 11 75 417821 , BE245149, Hs 82643, protein tyrosine kmase 9, cofιlιn_ADF,SS=M, 9 11 , 429 427157, U51166, Hs 173824, thymme DNA glycoεylase UDG,TM=M„ 9 06, 968
431341, AA307211, Hs 251531, proteasome (prosome macropain) subunit,, proteaεome,TM=M„ 905, 561 413367, NM_006517, Hs 75317, solute carrier family 16 (monocarboxylic, sugar tr,TM=Y„ 904, 579 437296, AA350994, Hs 20281, KIAA1700, Rhodanese,DSPc,TM=M„ 902, 575 418888, AU076801, Hs 89436, cadhenn 17, LI cadhenn (liver-intestin, cadheππ,TM=Y,SS=M, 894, 501 446406, A1553681 , Hs 348490, Arg/Abl interacting protein ArgBP2, Sorb.none, 891, 1 77
428820, AA436187, Hs 172631, integπn, alpha M (complement component , vwa,mtegπn_A FG GAP,TM=Y,SS=M, 885, 474 434398, AA121098, Hs 3838, serum-inducible kinase (SNK), pkιnase,POLO_box,TM-M„ 878, 454 453902, BE502341, Hs 3402, ESTs, none.none, 872, 371
433334, AI927208, Hs 231958, matnx metalloproteinase 28, Peptιdase_M10 none, 871, 428 446488, AB037782, Hs 15119, KIAA1361 protein, pkιnase,SS=M, 870, 371
450247, AF123303, Hs 24713, hypothetical protein, efhand,mιto_carr,TM=Y,SS=M, 868, 340 432101, AI918950, Hs 123642, EphA3, fn3,pkιπase,SAM,EPH lbd,TM=Y,SS=M, 862, 562 410763, AF279145, Hs 8966, hypothetical protein FLJ21776, none.none, 861, 1353 422278, AF072873, Hs 114218, fnzzled (Drosophila) homolog 6, Fz,Fnzzled,7tm 2,TM=Y,SS=M, 855, 482 425465, L18964, Hs 1904, protein kinase C, iota, pkιnase,DAG_PE bιnd,pkιnase_C,OPR,TM=M„ 8 50, 3 18
419111, AA234172, Hs 137418, ESTs, noπe.IRK, 847, 751
430024, AI808780, Hs 227730, integπn, alpha 6, ιntegnπ_A,FG-GAP,TM=Y,SS=M, 845, 346 447574, AF162666, Hs 18895, tousled like kinase 1, pkιnase,TM=M„ 845, 530 447217, BE465754, Hε 17778, neuropilm 2, CUB,MAM,F5 F8 type C,TM=M,SS=M, 844, 630 419034, NM.002110, Hε 89555, he opoietic cell kinase, SH2,SH3,pkιnase,TM=M„ 843, 487 405555, , , homeodomaiπ-interxting protein kinase 3, trypειn,TM=M„ 839, 068 417412, X16896, Hs 82112, interleukin 1 rxeptor, type I, ιg,TIR,TM=M,SS=M, 835, 474 405556, , , homeodomain-interxting protein kinase 3, trypsιn,TM=M„ 831, 087 ,
407687, AK002011, Hs 37558, hypothetical protein FLJ11149, lys ιg,FAD_Synth,ldh,ldh_C,pkιnaεe,SS=M, 828, 3 12 408051, AI623351, Hε 172148, ESTε, PH.RhoGAP.none, 8 27, 565
449523, NM_000579, Hε 54443, chemokine (C-C motif) rxeptor 5, 7tm_1,TM=Y,SS=M, 826, 549 429732, U20158, Hs 2488, lymphxyte cytosolic protein 2 (SH2 doma, SH2.SS-M, 8 24, 891 405204, , , NM 002086* Homo sapiens growth fxtor re, SH2,SH3,TM=M„ 823, 643 426806, T19228, Hs 172572, hypothetical protein FU20093, ank,pkιnase,UPF0073,SS=M, 820, 6 11 428428, AL037544, Hs 184298, cyclm-dependent kinase 7 (homolog of Xe, pkιnase,TM=M„ 8 18, 837
450375, AA009647, Hε 352537, a disintegnn and metalloproteinase doma, Reprolysιn,Pep_M12B_propep,dιειntegπn,Reprolyειn,Pep_M12B_propep,dιειntegrιn, 817, 1224 443303, U67319, Hs 9216, caspase 7, apoptosis-related cysteine pπ pkιnase,ICE_p10,ICE_p20,TM=M,SS=M, 8 15, 461 413132, NMJ06823, Hs 75209, protein kinase (cAMP-dependent, catalyti, PKI,SS=M, 8 15, 11 12 428513, BE220806, Hs 184697, Homo sapiens clone 23785 mRNA sequence, PSI.none, 8 13, 1328 429345, R11141, Hs 199695, hypothetical protein, K_tetra,SAM, 813, 1 15
425838, NM_014071 , Hs 159613, nuclear receptor coactivator RAP250, per, none,TM=M„ 8 12, 454 425836, AW955696, Hs 90960, ESTs, Cbl_N,Cbl_N2,Cbl_N3,UBA,zf-C3HC4,none, 8 11, 747 406366, , , sxreted fnzzled-related protein 4, trypsιn,SS=M, 805, 069
429663, M68874, Hs 211587, phospholipase A2, group IVA (cytosolic, , C2.PLA2 B,TM=M„ 804, 5 20 458946, AA009716, Hs 42311, ESTε, none,DSPc,Y_phosphatase, 802, 1 93
425280, U31519, Hε 1872, phosphoeπolpyruvate carboxykiπase 1 (sol, PEPCK,TM=M„ 797, 1933 445800, AA126419, Hs 32944, inositol polyphosphate4-phosphataεe, ty, none.none, 790, 11 44 449444, AW818436, Hε 351306, εolute earner family 16 (monxarboxylic, none,TM=Y,SS=M, 7 89, 700 426167, AF039023, Hs 167496, RAN binding protein 6, Armadιllo_seg,HEAT_PBS„ 783, 11 16 400408, S75765, , Homo εapiens delta CCK-B gene, partial c, 7tm_1,none, 781, 078
448362, AA641767, Hε 21015, hypothetical pratem DKFZp564L0864 εimil, sugar_tr,TM=Y,SS=M, 778, 702 457670, AF119666, Hs 23449, insulin rxeptor tyrosine kinase substra, SH3,TM=M„ 775, 263 409799, D11928, Hs 76845, phosphoseπne phosphatase-like, Hydrolase,TM=M„ 772, 268 447887, AA114050, Hs 19949, caspaεe 8 apoptosis-related cysteine pr, ICE p10,ICE_p20,DED,TM=M„ 768, 240 421684, BE281591, Hs 106768, hypothetical protein FLJ10511, Armadιllo_seg,SS=M, 749, 6 57
434699, AA643687, Hε 149425, Homo εapieπs cDNA FLJ11980 fis, clone HE Nucleosιde_tra2,none, 747, 253 417880, BE241595, Hs 82848, selectm L (lymphocyte adhesion molecule EGF,lectm_c,εushι,TM=M,SS=M 738, 560 436729, BE621807, Hs 351316, transmembrane 4 superfamily member 1, none,TM=Ϋ,SS=M, 7 29, 578 428970, BE276891 , Hs 194691 , retinoic acid induced 3, 7tm_3,TM=Y,SS=M, 726, 11 00
426761, AI015709, Hs 172089, PORIMIN Pro-oncosis rxeptor inducing me none,TM=Y,SS=M, 725, 7 22
413880, AI660842, Hs 110915, interleukin 22 receptor, Tιssue_fac,TM=Y,SS=M, 7 24, 098
418945, BE246762, Hs 89499, arachidonate 5 Iipoxygenase, lιpoxygenaεe,PLAT,TM=M„ 722, 645 413441 , AI929374, Hε 75367, Src-like adapter, SH2,SH3,TM=M„ 720, 572
426158, NM_001982, Hs 199067, v-erb b2 avian erythroblastic leukemia v, Furm lιke,pkιnase,Recep_L_domaιn,Fuπn-lιke pkinase.Recep L.domain Peptidase M24 7 13, 397
428474, AB023182, Hs 184523, KIAA0965 protein pkmase,TM=M , 7 13, 543
421582, AI910275, Hs 350470, trefoil factor 1 (breast cancer, estroge, trefoιl,Gastπn,SS=M, 708 21 61
449843, R85337, Hs 24030, solute earner family 31 (copper traπspo, none,TM=Y,SS=M, 707, 6 18 452110, T47667, Hs 28005, Homo sapiens cDNA FLJ11309 fis, clone PL, pkinase Activin.recp.πone, 694, 482
451295, AI557212, Hs 17132, ESTs Moderately similar to I54374 gene , pkmase.DAG.PE bιnd,pkιnase_C,OPR,πone, 692, 1534
430680, AW138724, Hs 168974, ESTs, Highly similar to ALU7.HUMAN ALU S, Y_phosphatase,Adaptιπ_N,Y_phosphatase 688, 1 94
441600, AA939347, Hs 127223, Homo sapiens cysteine knot protein (ZSIG, 7tm_1,ldLrecept_a,LRR,SS=M, 686, 097
410687, U24389, Hs 65436, lysyl oxidase-like 1 , Lyεyl_oxιdase,SS=M, 683, 724 425009, X58288, Hs 154151 , protein tyrosine phosphatase, receptor t fn3,ιg,Y_phosphatase,MAM TM=Y,SS=M, 683, 11 43
400539, , , Target Exon πoπe,TM=M„ 670, 1 19
431113, AK000673, Hs 274337, hypothetical protein FLJ20666, pkιnase,TM=M„ 665, 221
445280, AW055063, Hs 343220, v-crk avian sarcoma vims CT10 oncogene , SH2,SH3,none, 661, 1066
425834, NM_001639, Hs 1957, amyloid P component εerum, pentaxιn,TM=M,SS=M, 657, 220 435706, W31254, Hs 7045, GL004 protein, PDEase.GAF.πoπe, 655, 11 44
415906, AI751357, Hs 288741, Homo sapiens cDNA FLJ22256 fis clone H, Ephπn.none, 645 5 25
408308, AL033377, Hs 44197, hypothetical protein DKFZp564D0462, none.none, 642, 9 14
432336, NM_002759, Hs 274382, protein kinase, interferon-inducible dou, dsrm,pkιnase,TM=M„ 642, 4 12
417874, BE616160, Hs 82829, protein tyrosine phosphatase, non rxept, Y_phosphatase,TM=Y„ 642, 226 446872, X97058, Hs 16362, pyπmidinergic rxeptor P2Y, G-protein c, 7tm 1,TM=Y,SS=M, 641, 454
444006, BE395085, Hs 10086, type I transmembrane protein Fn14 ldl_rxept_a,PKD,MHC_l,TM=M SS=Y, 638, 355
412970, AB026436, Hs 177534, dual specificity phosphatase 10, Rhodaπese,DSPc,SS=M, 6 35, 495
422583, AA410506, Hs 27873, KIAA0874 protein, ank.G-alpha TM=M„ 635, 356
452355 N54926, Hs 29202, G protein coupled rxeptor 34, 7tm 1.0ATP C,TM=Y„ 632, 11 02 422282, AF019225, Hs 114309, apolipoprotein L, MotA_ExbB,TM=Y,SS=M, 632, 5 15
407235, D20569, Hs 169407, SAC2 (suppressor of xtin mutations 2, y, none.Ribosomal S13 Galxtoεyl_T,Zιp,adh_εhort zf C3HC4, 630, 8 35
428486, AW583497, Hs 184604, pancreatic polypeptide, hormone3,TM=M,SS=Y, 629, 351
408847, AW290997, Hs 30348, ESTs pkιnase,ιg,none, 628, 363
428179, AI127772 Hs 279696, serum/glucxorticoid regulated kinase Ii, pkιπase,PX,pkιnase_C,SS=M, 628, 350 443614, AV655386, Hs 7645, fibπnogen, B beta polypeptide, none none, 626, 748
425354, U62027, Hs 155935, complement component 3a rxeptor 1, 7tm_1,TM=Y,SS=M, 625, 398 448888, AW196663 Hs 200242, caspase recruitment domain protein 6, CARD,TM=M„ 621, 4 10
428180, AI129767, Hs 182874, guanine nuclxtide binding protein (G pr, G-alpha,arf,TM=M„ 6 18, 462 409245, AA361037, Hs 356436, tRNA lεopeπtenylpyrophoεphate tranεferaε, Armadιllo_seg,TM=M„ 617, 11 15 417952, AI192838, Hs 372643, dual specificity tyrosine (Y) phosphoryl, pkinase.none, 6 17, 305
445701, AF055581, Hs 13131, lymphxyte adaptor protein, SH2,PH,TM=M„ 6 16, 11 90
425910, AA830797, Hs 184760, CCAAT-box-binding transcription fxtor, none,TM=M„ 6 10, 2 96
426797, AW936258, Hs 342849, ADP-nbosylation fxtor-like 5, arf.Ca chaππel_B,SH3, 603, 3 17
408331, NM 007240, Hs 44229, dual spxificity phosphataεe 12, DSPc,TM=M„ 599, 255 441384, AA447849, Hs 288660, Homo sapienε cDNA FLJ22182 fiε, clone H, 7tm_3,none, 597, 13 12
414217, AI309298, Hs 279898, Homo sapienε cDNA FLJ23165fis, clone L, none,NA,NA, 592, 647
418506 AA084248, Hs 85339, Unknown protein for MGC 29643, none.none, 591, 1 94
436345, AA873008, Hs 121572, ESTs, CARD,BIR,zf-C3HC4,CARD,BIR,zf-C3HC4, 590, 1 40
414087, W19712, , gb zb36d03 r1 Soares_parathyroιd_tumor_N, pkinase.none, 585, 090 430396, D49742, Hs 241363, hyaluronan-binding protein 2, ank,death,ZU5,EGF,kπngle,trypsιn,Nebulιn,UM,SS=M, 577, 1 24
431385, BE178536, Hε 11090, membrane-εpaπmng 4-domaιns, subfamily A, none.none, 571, 400
427557, NM.002659, Hs 179657, plasminogen xtivator, urokmase rxepto, UPAR_LY6,ET,PLA2_ιnh,SS=M, 571, 383
414171, AA360328, Hs 865, RAP1 A, member of RAS oncogene family, pkιnaεe,DAG_PE-bιπd,RBD,raε,DC1,GFP,TM=M„ 569, 307
418870, AF147204, Hε 89414, chemokine (C-X-C motif), rxeptor 4 (fus, 7tm 1,7tm_2,TM=Y,SS=M, 568, 1292 425317, AW205118, Hs 210546, interleukin 21 rxeptor, none,TM=Y,SS=M, 560, 545
417863, AB000450, Hs 82771, vaccinia related kinase 2, pkιnase,TM=M„ 5 59, 4 19
400151, , , Eoε Control, AT_hook,DNA_mιε_repaιr,HATPase_c,UQ_con,TM=M„ 553, 8 13
450139, AK001838, Hs 355608, serum/glucxorticoid regulated kinase, none.none, 552, 861
418203, X54942, Hs 83758, CDC28 protein kinase 2, CKS„ 552, 1004 433556, W56321, Hs 111460, calcium/calmodulin-dependent protein km, pkinase.none, 551, 675
424701, NMJ05923, Hs 151988, mitogen-xtivated protein k ase kinase , pkιnase,TM=M„ 547, 458
415875, AA894876, Hε 5687, protein phoεphatase 1B (formerly 2C), ma, PP2C,TM=M„ 543, 530
408761, AA057264, Hs 238936, ESTs, Weakly similar to (defline not ava, 7tm_1 ,none, 542, 259
415444, BE247295, Hs 78452, solute earner family 20 (phosphate tran, PH04,UM,TM=M„ 537, 869 444184, T87841 , Hs 282990, Human DNA εequence from clone RP1-28H20 , pkιnase,RI01 ,APH,KOW,TM=M , 5 36, 332
410434, AF051152, Hs 63668, toll like rxeptor 2, LRR,LRRCT,TIR,TM=M,SS=M, 536, 394
429023, NM_000312, Hs 2351, protein C (inxtivator of coagulation fa, EGF,trypsιn,gla,SS=M, 531, 430
421559, NM.014720, Hs 105751, Ste20-related seππe/threomne kmase, pkmase,UVR,TM=M„ 531, 326
429922, Z97630, Hs 226117, H1 histone family, member 0, lιnker_hιstone,TM-M„ 527, 3 12 440682, AW362152, Hs 27181, nuclear rxeptor binding fxtor-2, cyclm,bZIP,TM=M„ 526, 482
411558, AA102670, Hs 70725, gamma-aminobutyπc acid (GABA) A rxepto, Neur_chan_LBD,Neur_chan_memb,TM=Y,SS=M, 5 25, 11 26
428234, U93553, Hs 183123, nuclear receptor subfamily 5, group A, m, hormone.rx,zf C4,SS=M, 520, 1 11
408683, R58665, Hs 46847, TRAF and TNF rxeptor-associated protein, Exo_endo_phos,TM=M„ 5 19, 625
408657, AA782601, Hs 173328, ESTs, B56,none, 5 18, 547 438746, AI885815, Hs 184727, Human melanoma assxiated antigen p97 (m, tranεfemn,Guanylate_kιπ,PDZ,SH3, 5 17, 402
438698, AW297855, Hε 361171, ESTε, Weakly similar to I38022 hypotheti, lipoxygenase.PLAT.none, 5 16, 291
442200, AW590572, Hs 235768, ESTs, none.none, 511, 422
418738, AW388633, Hs 6682, solute earner family 7, (cationic ammo, none.none, 508, 271
419088, AI538323, Hs 367688, integnn, beta 8, ιntegπn_B,none 507, 353 414555, N98569, Hs 76422, phospholipase A2, group HA (platelets, , phoslιp,TM=M,SS=Y, 505, 342
408414, AI114688, Hs 193400, ESTs, Weakly similarto 2109260A B cell , fπ3,ιg,TM=Y,SS=M, 505, 341
430407, H23551, Hs 30974, ESTs, pkmase.PBD.none, 503, 1 63
427127, AW802282, Hs 22265, pyruvate dehydrogenase phosphatase, PP2C,none, 500, 5 14 452194, AI694413 Hs 373599, Ubiquitin like protein FAT10""' - diubiq, none.none, 498, 265 410073, AW408163 Hs 58488, catenin (cadhenn assxiated protein), a, Stathmm,Vιπculm,SS=M, 497, 1060 409430 R21945 Hs 346735, splicing factor, arginine/serme πch 5, DSPc.Rhodanese.none, 495 2 87 432841 , M93425, Hs 62, protein tyrosine phosphatase, non rxept, Y.phosphatase,SS=M, 488, 21 69 433470, AW960564, Hs 351316, transmembrane 4 superfamily member 1 , none,TM=Y,SS=M, 488, 460
418529, AW005695, Hs 250897, TRK-fused gene, Band_41,ERM,pkιπase,LRR LRRCT.MAM Nucleoplasmin.Tropomyosin OPR filament bZIP.G-ga ma M,DUF164,TM=M, 479,
547 421425, AK001564, Hs 104222, hypothetical protein FLJ10702, efhand kazal,arf,ras,7tm_1,TM=M„ 475, 541 414135, NMJ04419, Hs 2128, dual specificity phosphatase 5, Rhodanese,DSPc,Y_phosphatase,TM=M„ 474, 976 417640, D30857, Hs 82353, protein C rxeptor, endothelial (EPCR), none,TM=M,SS=M, 473, 468
430630, AW269920, Hs 2621, cystatm A (stefin A), cystatιn,TM=M„ 466 561 452239 AW379378, Hε 356289, protein tyrosine phosphatase, receptor t, none.none, 463, 662 427333, AF067797, Hs 176658, aquapoπn 8, MIP,TM=Y,SS=M, 463, 080
431890, X17033, Hs 271986, integnn, alpha 2 (CD49B, alpha 2 subuni, vwa,ιntegnπ_A,FG-GAP,TM=Y,SS=M, 458, 11 38 428065, AI634046, Hε 157313, ESTε ICE p20,DED,ICE_p10,ICE_p20,DED, 455, 4 51
428582, BE336699 Hs 185055, BENE protein, πone,TM=Y,SS=M, 454, 876 416224, NM.002902, Hs 79088, reticulocalbm 2, EF-hand calcium bmdin, efhand,SS=M, 454, 1957
450056, BE047394, Hs 8208, ESTs, Weakly similarto S71512 hypotheti, ABC_tran,ABC_membrane,ιg,MHC_ll_beta,SRP54,proteasome ABC_membrane,ABC tran, 449, 1047 414987, AA524394, Hs 294022, hypothetical protein FU14950, SH2,TM=M„ 441, 7 27 447232, AW499834, Hs 327, interleukin 10 rxeptor, alpha none,TM=M,SS=M 441, 10 25
433208, AW002834, Hs 24095, ESTs, art Ca_chaπnel_B,SH3, 439, 12 14 403208, , , Target Exon, lectin.c.none, 437, 076
440486, BE243513, Hs 7212, hypothetical protein PP1044, LRR.PAAD.DAPIN AAA,CARD,NB-ARC,NA,NA, 436, 10 34 414278 AA330116, Hs 355877, Human glucoεe transporter pseudogene, none.none, 435, 795 424833, NM.003894, Hs 153405, period (Drosophila) homolog 2, PAS,SS=M, 434, 623
422573, AW297985, Hs 295726 integnn, alpha V (vitronectin rxeptor, FG-GAP,ιntegπn_A none, 432, 585 418721, NM.002731, Hs 87773, protein kinase, cAMP-dependent, catalyti, pkιπase,pkιnaεe_C,SS=M, 431, 309 412330, NM 005100, Hε 788, A kinase (PRKA) anchor protein (gravm) , none,TM=M„ 425, 1274 421939, BE169531, Hs 109727, TAK1-bιndιng protein 2, KIAA0733 protein, zf RanBP,CUE,TM=M„ 425, 1254 414774, X02419, Hs 77274, plaεminogen xtivator, urokmase, krιngie,trypsιn,planLthιonιns,SS=M, 424, 691
418526, BE019020, Hε 85838, εolute carrier family 16 (monxarboxylic, none,TM=Y,SS=M, 422, 527 415801, R24219, Hs 278443, Fc fragment of IgG, low affinity lib, re, ιg,TM=Y„ 4 16, 722 417866, AW067903, Hs 82772, collagen, type XI alpha 1, Collagen,COLFI,TSPN,lamιnιn_G CorA,SS=M, 4 16, 9 27 445496, AB007860, Hs 12802, development and differentiation enhancin, SH3,ank,PH,ArfGap,TM=M„ 415, 2343 436075, BE090176, Hs 179902, transporter-like protein, none,TM=Y,SS=M, 4 14, 376
414462, BE622743, Hs 301064, arfaptm 1, none.none, 408, 1343
435730, AB020635, Hs 4984, KIAA0828 protein, AdoHcyase,TrkA-N,2-Hacιd_DH_C,TM=M„ 406, 9 12 431681, AK000378, Hs 267566, hypothetical protein FLJ20371, sugar_tr,TM=Y„ 404, 1005 429379, NM_014840, Hs 200598, KIAA0537 gene product, pkιnase,RI01,TM=M„ 400, 635 429061, Y14039, Hs 195175, CASP8 and FADD like apoptosis regulator, ICE_p20,DED,TM=M„ 398, 566
405203, , , NM.002086* Homo sapiens growth fxtor re, SH2,SH3,TM=M„ 395, 1771
409335, NM_001502, Hs 53985, glycoprotein 2 (zymogen granule membrane, zona_pellucιda,TM=M,SS=M, 394, 058 446006, NM_004403, Hs 13530, deafness, autosomal dominant 5, none,TM=M,SS=M, 389, 759 413899, AF083892, Hs 75608, tight junction protein 2 (zona occludens, SH3 PDZ,Guaπylate_kιn,TM=M„ 384, 889 438000, AI825880, Hε 5985, non kmase Cdc42 effector protein SPEC2, none,TM=M , 383, 4 22
418054, NM_002318, Hs 83354, lysyl oxidaεe-like 2, SRCR,Lysyl_oxιdase,TM=M,SS=M, 381, 645 450285, AW383256, Hs 24752, spxtπn SH3 domain binding protein 1, SH3 TM=M„ 378, 849 417141, U22662, Hs 347353, nuclear rxeptor subfamily 1, group H, m, hormone_rec,zf-C4,SS=M, 377, 422 456376, AA663904, Hε 89862, TNFRSF1 A-assxiated via death domain, death,TM=M„ 368, 492 438113, AI467908, Hs 8882, ESTs, 7tm 1,none, 359, 12 12
414883, AA926960, Hs 348669, CDC28 protein kinase 1, CKS„ 358, 1093
429952, AF080158, Hs 226573, inhibitor of kappa light polypeptide gen, pkιπase,ubιquιtιn,Enterotoxιn_A,PH04,pkιnase,ubιquιtm, 3 57, 5 10 415088, AI077288, Hs 374374, serum glucxorticoid regulated kinaεe, none.none, 356, 460 418478, U38945, Hε 1174, cyclm-dependent kinase inhibitor 2A (me, ank,, 355, 452 448569, BE382657, Hs 21486, εigπal tranεducer and xtivator of tranε, SH2,STAT,STAT bιnd,STAT_prot,TM=M„ 354, 819
434608, AA805443, Hε 179909, hypothetical protein FU22995, πone,TM=M„ 352, 970 400288, X06256, Hs 149609, integπn, alpha 5 (fibronxtin receptor,, ιntegπn_A,FG-GAP,TM=Y„ 345, 644 445350, AF052112, Hs 12540, lysophospholipase I, abhydrolase_2,TM=M„ 341, 603 418255, AW135405, Hs 37251, ESTε, pkιπase,none, 341, 1397 408822, AW500715, Hs 57079, Homo sapiens cDNA FLJ13267 fis, clone OV, PIP5K,none, 340, 897 i
426432, AF001601, Hs 169857, paraoxonase 2, Arylesterase,TM=M„ 3 39, 11 24 431629, AU077025, Hs 265827, interferon, alpha-inducible protein (clo, none,TM=M,SS=Y, 3 39, 5 10 414291, AI289619, Hε 13040, G protein-coupled rxeptor 86, 7tm_1,TM=Y,SS=M, 338, 1025 457329, AI634860, Hε 247043, type 1 tumor necrosis fxtor rxeptor sh, Peptιdaεe_M1 ,SS=M, 338, 1378 411125, AA151647, Hε 68877, cytxhrome b-245, alpha polypeptide, none,TM=Y,SS=M, 336, 4 17
443710, AI928136, Hs 9691, Homo sapiens cDNA FLJ23249 fis, clone C, G-alpha,none, 332 2033 454294, AB000734, Hs 50640, JAK binding protein, SH2,TM=M„ 331, 694 408912, AB011084, Hs 48924, KIAA0512 gene product, ALEX2, Armadιllo_seg,TM=M,SS=M, 329, 307 426728, NM.007118, Hs 367689, tπple functional domain (PTPRF iπter∞L SH3,ιg,pkιnase,PH,εpxlnπ,RhoGEF,TM=M„ 327, 1490 427202, BE272922, Hs 173936, interieukin 10 rxeptor, beta, Tissue fx,TM=Y,SS=M, 324, 449
413076, U10564, Hs 75188, weel (S pombe) homolog, pkιnase,TM=M„ 324, 1227 425976, C75094, Hs 334514, NG22 protein, voltage CLC,TM=Y,SS=M, 323, 1340 417534, NM 004998, Hs 82251, myosin IE, SH3,myosm_head,IQ,TM=M„ 321, 1521 458097, AW341135, Hs 58104, ESTs, none SH3.PID, 321 , 734 437928, NM.005476, Hs 5920, UDP-N-xetylglucosamιne-2-epιmerase/N-ac, hexokmase,FGGY,ROK,Epιmerase_2,SS=M, 320, 838
425177, AF127577, Hs 155017, nuclear rxeptor interacting protein 1, none,SS=M, 3 19, 509 416094, AW995512, Hs 225977, nuclear receptor coacuvator 3, none.none, 318, 417
453489, AA300067, Hs 102000, hypothetical protein DKFZp434N185, F5 F8_type_C,pkιnase,Etε,F5 F8 type_C,pkιnase,Ets, 3 17, 788 414914, U49844, Hε 77613, ataxia telangixtasia and Rad3 related, FAT,FATC,PI3_PI4_kιnase,TM=M„ 3 16, 471 412767, AA233808, Hε 286241, protein kinaεe, cAMP-dependent, regulate, SH3,7tm_2,cadheπn GPS.Iaminin G.EGF.Iammin EGF,Sulfate_tranεp,STAS,cNMP bmdiπg.Rlla 3 16, 19 415662, AW972481, Hs 170610, ESTs, Highly similar to G01887 MEKkmas, pkinase.none, 3 16, 721 407786, AA687538, Hs 38972, tetraspan 1, transmembrane4,TM=Y,SS=M, 3 15, 2266 437175, AW968078 Hε 87773, protein kinaεe, cAMP-dependent catalyti, pkιnase,pkιnase_C,none, 3 14, 11 72 409270, BE090051, Hs 23120, PIST, fn3,pkιnase,PDZ,DUF139,TM=Y,SS=M, 309, 781 419591, AF090900, Hs 91393, Homo εapienε cDNA FLJ21887 fiε, clone H, PDZ,L27,TM=M„ 306, 546 447225, R62676, Hε 17820, Rho aεsociated, coiled coil containing p, PH,pkιnase,HR1,none, 304, 1305 412692, AF044288, Hε 74515, aryl hydrocarbon receptor nuclear transi, HLH.PAS.PAC TM=M„ 295, 12 28
409274, NM_003930, Hs 52644, SKAP55 homologue, SH3,PH,SS=M, 290, 1462 417707, AL035786, Hs 82425, actm related protein 23 complex, subun, none,TM=M„ 290, 11 00 427045, H86504, Hε 173328, protein phosphatase 2, regulatory subuni, B56,TM=M„ 289, 6 12 431177, NMJ03304, Hs 250687, transient rxeptor potential channel 1, ιon_trans,ank,TM=Y„ 289, 6 53 443426, AF098158, Hs 9329, chromosome 20 open reading frame 1, πoπe,TM=M„ 287, 9 18
418546, AA224827, , gb nc32g04 s1 NCI_CGAP_Pr2 Homo sapiens , vwa.integπn A,FG-GAP,none 286, 994 446668, W58353, Hs 285123 Homo sapiens mRNA full length insert cDN, NDK PH,Oxysterol_BP,SS=M, 285 1425 454080, AH 99711, Hε 576, fucoεidase, alpha-L- 1, tisεue, Alpha L_fucos,TM=M,SS=M 281, 2884 432874, W94322, Hs 279651 , melanoma inhibitory activity, SH3,TM=M,SS=Y, 280, 1053 433000, U26710, Hs 3144, Cas-Br-M (munne) ectropic retroviral tr, zf-C3HC4,UBA,Cbl_N,Cbl_N2,Cbl_N3„ 277, 1093
444488, AW192879, Hε 355660, ancient coπεerved domain protein 4, none.none, 277, 1258 417904, AI750762, Hε 82911, protein tyrosine phoεphatase type IVA, m, Y_phosphatase,DSPc,TM=M , 276, 1278 425204, NMJ02436, Hs 1861, membrane protein, palmitoylated 1 (55kD), SH3,PDZ,Guanylate_kιn,SS=M, 274, 571 419262, AA834664, Hs 29131, nuclear rxeptor coactivator 2, PAS,zf-C2H2,SET, 273 1250 410793, AW581906, Hs 66392, intersxtm 1 (SH3 domain protein), SH3,efhand,C2,PH,RhoGEF,M,SS=M 273, 9 84 446081, AA972412, Hs 13755, f-box and WD 40 domain protein 2 WD40,F-box,Rιbosomal L14,TM=M„ 271, 1229 414443, AU077268, Hs 76144, platelet-derived growth fxtor rxeptor,, ιg,pkιnase,TM=Y„ 271, 1053 452683, AI089575, Hε 374574, progesterone membrane binding protein, homeobox.none, 269, 1253 423533, NM 014339, Hs 129751 , interleukin 17 receptor, none,TM=Y,SS=M, 267, 859 422627, BE336857, Hs 118787, transforming growth factor, beta-induced, Fasciclm.ABC tran,ABC_membrane GTP_EFTU,TM=M,SS=M, 267, 1222 453915, AA588721, Hs 12284 ribosomal protein L44, noπe,T-box, 265, 638 416810, AF035606, Hs 80019, programmed cell death 6, efhaπd,TM=M„ 261, 1389 439658, AA332057, Hs 6639, hypothetical protein MGC15440, none,TM=M,SS=M, 258, 10 19 449924, W30681, Hs 146233, Homo sapienε cDNA FLJ22130 fiε, clone H, SH3,noπe, 256, 1904 412926, AI879076, Hε 75061, mxrophage myπstoylated alanine πch C , MARCKS SS=M 255, 1499
439237, AW408158, Hs 318893, ESTs, Weakly similar to A47582 B-cell gr, Fuπn-like pkinase.Rxep.L domaιn,YLP,none 252, 1471 409098, AA132672, Hs 7984, pleckstπn homology, Sec7 and coiled/coi, PH,Sx7,TM= , 251, 1451 413040, AA193338 Hε 12321, sodium calcium exchanger, Na Ca_Ex,TM=Y,SS=M, 249, 9 28 422070, AF149785, Hs 111126, pituitary tumor-transforming 1 mteracti, TCTP,TM=M,SS=Y, 245, 1249 452289, BE568205, Hs 28827, mitogen-activated protein kinase kinase , pkιnase,TM=M„ 244, 668 427657, AV652249, Hs 180107, polymerase (DNA directed), beta none,TM=M„ 243, 797 446287, BE247683, Hs 14611 , dual specificity phosphatase 11 (RNA/RNP, DSPc,SS=M, 241 , 951 410017, AW952426, Hs 109438, Homo sapiens clone 24775 mRNA sequence, none.none, 241, 1401 424756, AW504657, Hs 152931, lamiπ B rxeptor, ERG4_ERG24,FKBP,TM=Y„ 240, 598 447580, AI953360, Hs 88201 , ESTε, none.none, 236, 11 63
426276, AW881411, Hs 169078, hypothetical protein FLJ23018 hormone rx,zf-C4,TM=M„ 234, 1334 424441, X14850, Hs 147097, H2A histone family, member X, hιstone,CBFD_NFYB_HMF„ 233, 1217 429623, NM.005308 Hs 211569, G protein-coupled rxeptor kinase 5, pkιnase,RGS,TM=M„ 232, 1580 439866, AA280717, Hε 6727, Ras-GTPase xtivatmg protein SH3 domain, rrm,NTF2,TM=M„ 232, 1248 453648, W21493, Hs 28329, hypothetical protein FLJ14005, none.none, 231, 13 19
443951, F13272, Hs 356835, ferntm, light polypeptide, PMP22_Claudιn,none, 231, 851 453327, AW500180, Hε 356109, tryptophanyl-tRNA εynthetaεe, rrm,vwa,FG-GAP, 230, 1302 439256, AA322302, Hs 183302, PCTAIRE protein kinase 2, none none, 226, 1036
424467, AI929392, Hε 350026, DnaJ (Hsp40) homolog, subfamily B, membe, DnaJ,pkιnase,UBA,pkιπase C,SS=M, 226, 11 82 426440, BE382756, Hs 169902, solute camerfamily 2 (facilitated glu, sugar_tr,TM=Y,SS=M, 226, 1254 456607, AI660190, Hε 106070, cyclm-dependent kmase inhibitor 1C (p5, CDI,TM=M„ 225, 1311 423960, AA164516, Hε 136309, SH3-contaιnιng protein SH3GLB1, SH3,πone, 2 20, 2005 424058, AL121516, Hs 138617, thyroid hormone rxeptor interxtor 12, HECT,WWE,TM=M„ 220, 1338 446644, NM_003272, Hs 15791, tranε embrane 7 εuperfamily member 1 (up, noπe,TM=Y,SS=M, 2 18, 1568 411218, H46440, Hε 180628, dynamin 1-lιke, dynamιn_2,dynamιn,GED,none, 218, 1383
414721, X90392, Hε 77091, πboεomal protein L10, Exo endo_phos,Rιbosomat L10e,Acyltransferaεe,SCP,TM=M,SS=M, 2 14, 11 24 421759, AA027968, Hs 107979, small membrane protein 1, none,TM=Y,SS=M, 214, 1403 416240, NM.001981, Hs 79095, epidermal growth fxtor rxeptor pathway, efhand,DUF164,TM=M„ 2 13, 1286 435521, W23814, Hs 6361, mitogen-xtivated protein kinase kinase , none.none, 2 12, 11 08 409340, BE174629, Hs 321130, hypothetical protein MGC2771, aa_permeases,pyπdoxal_deC,bromodomaιn,PHD,MBD,AT hook,DDT,PI3 PI4 kιnase,FAT,FATC,BolA,RUN,TM=M„ 2 12, 1405 453064, R40334, Hs 89463, potassium large conductance calcium xb, none.none, 2 12, 8 96 409223, AA312572, Hs 362852, phosphoιnoειtιde-3-kιnaεe, regulatory εu, SH2,SH3,RhoGAP,none, 208, 11 60 414482, S57498, Hs 76252, endothelin rxeptor type A, 7tm_1,TM=Y,SS=M, 206, 1423 414496, W73853, Hs 355424, ESTs, pkιnase,F5_F8_type_C,adh_short,noπe, 205, 1345
450455, AL117424, Hs 25035, chloride intracellular channel 4, noπe.TNF, 205, 1904 449906, NM 005638, Hs 24167, synaptobrevm-like 1, εynaptobrevιn,NTF2,TM=Y„ 204, 1334 422112, BE540240, Hs 111783, Lsm1 protein, Sm,BAG,SS=M, 203, 1260 434935, BE561824, Hε 273369, uπcharxteπzed hematopoietic stem/proge, none,TM=M„ 202, 1052 433427, AI816449, Hs 171889, cholinephosphotransferase 1, SH2,CDP-OH_P_transf,TM=M„ 202, 1687
410850, AW362867, Hs 302738, Homo εapieπs cDNA FLJ21425 fis, clone C, Sulfate transp.STAS.HMG box, 202, 937 440481, AA182907, Hε 7200, Homo εapienε, clone MGC 16714, mRNA, com, pkιnase,RCC1 ,TM=M„ 202 1231 434645, AF255303, Hs 112227, membrane-assxiated nucleic xid binding, zf-CCCH,gpdh,Adeno_E1B_55Kzf-C3HC4,TM=M„ 200, 9 15 410113, AW996564, Hs 250824, Homo sapiens cDNA FLJ23435 fiε, clone H, pkinase.none, 1 99, 1064 414636, AL120259, Hs 76691, staππm, none,TM=M,SS=Y, 1 95, 772
408176, AK001553, Hs 43436, adenylate kinase 3 alpha like, adenylatekmase.πone, 1 95, 1495 422690, AU077275, Hε 119222, suppression of tumoπgemcity 13 (colon , TPR,TM=M„ 1 94, 1091 427881, BE538296, Hs 323834, cytxhrome c oxidase subunit Va, none.GKAP, 1 93, 20 57 433387, L76528, Hs 3260, preεenilin 1 (Alzheimer diεease 3), Presenιlm,7tm_3,oxιdored_q5 N,TM=Y„ 1 92, 1258 453938, AF082569, Hε 36794, D type cyclin mterxting protein 1, B56,TM=M„ 1 90 1274
433592, NM_004642, Hs 3436, deleted in oral cancer (mouse, homolog) , πone,TM=M„ 1 89, 2327
447791, BE241859, Hs 19575, CGI-11 protein, V-ATPase_H Armadιllo_εeg,TM=M„ 1 88, 1282
426359, AA376409, Hε 10862, Homo sapiens cDNA FU23313 fis, clone H, adenylatekmase.none, 1 88, 1495 432650, D00860, Hs 56, phosphoπbosyl pyrophosphate synthetase , none.none, 1 88, 1270 424250, AF073310, Hs 143648, insulin rxeptor subεtrate 2, PH,IRS,TM=M„ 1 86, 19 50 424482, BE268621, Hs 149155, voltage-dependent anion channel 1 , Euk_poππ,SS=M, 1 85, 11 29 425335, BE394327, Hs 296267, follistatin-like 1, efhand,kazal,arf,ras,7tm_1,TM=M„ 1 85 1362 426122, NM.006925, Hs 166975, splicing factor, arginine/seπne πch 5, rrm,SS=M, 1 83, 1088
451579, AW607731, Hs 26670, Human PAC clone RP3 515N1 from 22q11 2-q, kπngle,TM=Y,SS=M, 1 83, 2035 428901, AI929568, Hs 146668, KIAA1253 protein, 7tm_2,UPF0073,TMS_TDE,TM=Y,SS=M, 1 83, 1900 453963, AA040311, Hs 28959, ESTs, pkιnase,Actιvιn_recp,none, 1 82, 1525 417414, AA434589, Hs 367676, dUTP pyrophosphatase, dUTPase.KRAB,, 1 81, 1420 414521, D28124, Hε 76307, neuroblaεtoma, εuppreεsion of tumoπgeni, DAN,TM=M,SS=M, 1 81, 2229
425356, BE244879, Hs 155939, inositol polyphoεphate 5-phosphatase, 14, Exo_endo_phoε,SH2,TM=M„ 1 80, 1830 417733, AL048678, Hs 82503, H sapiens mRNA for 3 UTR of unknown prot, none.NA.NA 1 80, 628 424805, AF230904, Hs 153260, c-Cbl interacting protein, SH3,TM=M„ 1 80, 11 99 420747, BE294407, Hs 99910, phosphofructokinase, platelet, PFK,TM=M„ 1 79, 2525 416819, U77735, Hε 80205, pirn 2 oncogene, pkιnase,SS=M, 1 78, 1525
437708, AB033020, Hs 5801 , Kl AA1194 protein, LRR Exo_endo_phos,TM=M„ 1 77, 11 11 439877, H39685, Hs 258730, tryptase beta 1, pkιnase,SS=M, 1 77, 21 91 440256, U23841, Hs 18851, hypothetical protein FLJ10875, none.UBA.UBX, 1 76, 1295 425367, BE271188, Hs 155975, protein tyrosine phosphatase rxeptort, none,TM=M,SS=Y, 1 76, 21 01 414703, BE243877, Hs 374366, ATPase, Na' transporting, beta 3 polypep Na.K-ATPase TM=Y,SS=M, 1 75, 2003
443693, AI344782, Hs 349261, DnaJ (Hsp40) homolog subfamily C, membe, rrm,DnaJ,TPR,TM=M„ 1 75, 1329 437412, BE069288, Hs 34744, Homo sapiens mRNA, cDNA DKFZp547C136 (fr, ABC_tran,GTP_EFTU,ABC_membrane,none, 1 75, 875 413796, AW408094, Hs 75545, interleukin 4 receptor, fn3,granulιn,TM=M,SS=M, 1 74, 1473 438438, AA257992, Hs 50651, Janus kinase 1 (a protein tyrosine kmas, pkιnase,SH2,adenylatekmase,none, 1 73, 24 10 429655, U48959, Hs 211582, myosin, light polypeptide kmase, pkιnase,fn3,ιg,noπe, 1 73, 31 59
421456, AW579842, Hs 104557, hypothetical protein FLJ10697, zf C2H2,DUF18,efhand C2,Pl-PLC-Y,PI-PLC-X,TM=M„ 1 73, 1687 444252, R21135, Hs 54985, ESTs, none.none, 1 71, 1040
442819, BE622721, Hs 284275, Homo sapiens PAK2 mRNA, complete eds, noπe,pkιnase,PBD, 1 69, 1402 447918, AI129320, Hs 115175, ESTs, Highly similar to JC5818 gamma xt, pkιnase,SAM,none, 1 69, 17 14 429279, AB018271, Hs 198689, KIAA0728 protein, Myosm_taιl,efhand,spxtπn,GAS2,Myosιn_taιl, 1 68 1421
450440, AB024334, Hs 25001, tyrosine 3-monooxygenase/tryptophan 5-mo, 14-3-3,TM=M„ 1 67, 2467 413423, AU076684, Hs 75350, vinculm, Vinculin.noπe, 1 65, 2928
420972, AW814616, Hs 31431, hypothetical protein FLJ12171, Fructosamιn_kιn,SS=M, 1 65, 1075 416884, M60484, Hs 80350, protein phosphatase 2 (formerly 2A), cat Metallophos,SS=M, 1 63, 2455 436719, Y11192, Hs 5299, aldehyde dehydrogenase 5 family, member , lιpxalιn,aldedh,ubιquιtιn,IRK,SS=M, 1 61, 11 20
419223, X60111, Hs 1244, CD9 antigen (p24), transmembrane4,TM=Y,SS=M, 1 61, 1493 414176, BE140638, Hs 75794, EDG-2 (endothelial differentiation, lys, 7tm_1,CRCB,TM=Y„ 1 61, 803 431476, BE612705, Hs 256697, histidine tnad nucteotide-bmding prote, HIT,SS=M, 1 60, 2437 412347, AW970026, Hs 73818, ubiquinol-cytochrome c reductaεe hinge p, UCRJinge.G alpha arf,TM=M„ 1 59, 18 09 423804, AW403448, Hs 1706, interferon stimulated transcnption fxt, IRF,zf-C3HC4,IBR,zf-RanBP,TM=M„ 1 59, 10 99
426552, BE297660, Hs 170328, moeεin, Band_41,ERM,pkιnase,LRR,LRRCT,MAM,Nucieoplasmιn,Tropomyoειn,OPRfιlament,bZIP,G-gamma,M,DUF164,TM=M„ 1 58, 2597 428216, M18468, Hs 183037, protein kinase, cAMP-dependent, regulato, cNMP_bιπdιng,Rlla,SS=M, 1 56, 1058 421251, Z28913, Hs 102948, enigma (LIM domain protein), LIM,PDZ,SS=M, 1 56, 1351 448581, NM 002709, Hs 21537, protein phosphatase 1, catalytic subunit, none.none, 1 55, 1233 417098, AB017365, Hs 173859, frizzled (Drosophila) homolog 7, Fπzz!ed,Fz,7tm_2,toxιn_2,TM=Y,SS-M, 1 55, 1377
437076, AA961260, Hs 5443, BCL2-aεε∞ιated athanogene 5, BAG,Hanta_nuclexap,TM=M„ 1 54, 1093 426653, AA530892, Hs 171695, dual specificity phosphatase 1, Rhodanese,DSPc,Y_phosphatase,TM=M„ 1 54, 11 88 421143, AB024536, Hs 102171, immunoglobulin superfamily containing Ie, ιg,LRR,LRRNT,LRRCT,TM=M,SS=M, 1 53, 2305 414457, AW514320, Hs 76159, ATPase, H transporting, lysosomal (vxuo, pkιnase,ATP-synLC,none, 1 53, 3259 414382, AW380339, Hε 8068, hematopoietic PBX terxting protein, M,TM=M„ 1 52, 866
450998, BE387614, Hε 25797, splicing fxtor 3b, subunit 4, 49kD, rrm,TM=M„ 1 52, 11 74 402705, , , xtivator of S phase kinase, AhpC-TSA,TM=M,SS=M, 1 51, 2685 426268, AF083420, Hs 168913, εeπne/threonine kinase 24 (Ste20, yeast, pkιπase,SS=M, 1 50, 2404 414604, AU076649, Hs 76556, growth arrest and DNA-damage-inducible 3, none,TM=M„ 1 50, 1435 445584, AF217518, Hs 8360, PTD012 protein, none,SS=M, 1 49, 1200
407232, X04526, , gb Human liver mRNA for beta-subunit εig, WD40,TM=M„ 1 49, 1932
424206, NM_003734, Hε 198241, amine oxidaεe, copper containing 3 (vaεc, Cu_amιne_oxιd,Cu_amιne_oxιdN2,Cu_amιne_oxιdN3,TM=M,SS=M, 1 48, 1321 458761, AF090922, Hs 152738, mitxhondπal πbosomal protein L11, ER_lumen_recept,Rιbosomal_L11,Rιbosomal_L11_N,TM=Y,SS=M, 1 48, 1250 426340, Z97989, Hs 169370, FYN oncogene related to SRC, FGR, YES, BNR,SH2,SH3,pkιnase,TM=Y,SS=M, 1 48, 1775 414166, AW888941, Hε 75789, N-myc downεtream regulated, DEAD,helιcase_C,rrm,Ndr,Cys_knot,TIL,vwa,vwc,vwd,IQ,Rlla,abhydrolase,TGF- beta,DUF139,TPR,DSPc,tsp_1,Rιbosomal S21,rvp,TM=M„ 1 46, 2047 452516, AA058630, Hs 29759, RNA POLYMERASE I AND TRANSCRIPT RELEASE , none,SS=M, 1 46, 1272 414240, AL046742, Hs 75842, dual-specificity tyrosine (Y)-phosphoryl, pkmase,SS=M, 1 45, 1438 420532, AA248016, Hs 194110, hypothetical protein PRO2730, pkιnase,WD40,SS=M, 1 43, 1392 402575, , , Rho GTPaεe xtivahng protein 1, PAP2,TM=Y,SS=M, 1 43, 1371
414765, X07854, Hε 77269, guanine nucleotide binding protein (G pr, G-alpha,arf,TM=M„ 1 41, 2462 448423, BE390905, Hs 21198, traπslxase of outer mitxhondπal membr, TPR,TM=M,SS=M, 1 41, 1070 422587, AI879352, Hs 118625, hexokmase 1, hexokιnase,hexokιnase2,TM=M„ 1 41, 1931 415995, NM.004573, Hs 355888, phospholipase C, beta 2, C2,PI-PLC-Y,PI-PLC-X,TM=M„ 1 40, 11 21 446108, AL036596, Hs 42322, A kinase (PRKA) anchor protein 2, Paralemmm,TM=M„ 1 40, 1398
427721, AI582843, Hs 180455, RAD23 (S cerevisiae) homolog A, ubιquιtm,UBA,ιntegπn_B,SS=M, 1 39, 1501 417891, W79410, Hs 82887, protein phosphatase 1, regulatory (mhib, none,TM=M„ 1 39, 1597 427373, AB007972, Hs 130760, myosin phosphatase, target subunit 2, aπk,TM=M„ 1 39, 1449 446334, U52427, Hs 14839, polymerase (RNA) II (DNA dirxted) polyp, COX8,SHMT,MIF,GST_C,EF1G_domaιn,GST_N,S1,Fz,Fπzzled,calretιculιπ,7tm_2,rrm,PAP_assx,TM=Y,SS=M, 1 38, 1258
447042, AB035863, Hs 182217, succmate-CoA ligase, ADP-forming, beta , lιgase-CoA,ATP-grasp,Zιp,CPSase_L_D2,GARS_B,TM=Y,SS=M, 1 37, 11 37 427705, AI870421, Hs 180394, signal rxogmtioπ particle 14kD (homolo, SRP14,TNFR_c6,SS=M, 1 37, 2205 425969, AW576265, Hs 301763, KIAA0554 protein, SH3,FCH,HR1,TM=M„ 1 37, 1368 433572, AL046859, Hs 3407, protein kinaεe (cAMP-dependent, catalyti, PKI,SS=M, 1 35, 1243 410597, W16518, Hs 279518, amyloid beta (A4) prxursor-like protein, Kunιtz_BPTI,A4_EXTRA,Coprogen_oxιdas,TM=Y,SS=M, 1 35, 2254
418424, Y13622, Hs 85087, latent transforming growth factor beta b, EGF,TB,spιdertoxιn,granulιn,ANF_receptor,SS=M, 1 34, 1209 442603, AL035719, Hε 303091, pleckstπn homology, Sx7 and coiled/coi, PH,Sec7,TM=M„ 1 34, 11 40 418043, AW377752, Hs 83341 , AXL receptor tyrosine kmase, fn3,ιg pkιnase,TM=Y,SS=M, 1 31, 1079 439278, AF077046, Hs 6518 ganglioside expression fxtor 2, MAP1_LC3,amιnotraπ_3,TM=M„ 1 31, 1589 425875 AU077333, Hs 160483 erythrocyte membrane protein band 7 2 (s, PBP,Band_7,TM=M„ 1 31, 1793 407744, AB020629, Hs 38095 ATP-binding cassette, sub family A (ABC1, ABC_tran,PRK,TM=Y,SS=M, 1 29, 1095 420679, X57152, Hs 99853 fibπllaπn CK_ll_beta,Fιbπllaππ,WD40,TM=M , 1 29, 1869 427397, AI929685, Hs 177656 cal odulin 1 (phosphorylase kinase, delt, efhaπd,RmaAD,SS=M, 1 29, 1568
424661, M29551, Hs 151531, protein phosphatase 3 (formerly 2B), cat Metallophos,TM=M„ 1 28, 1339 428950, BE311879, Hε 194673 phoεphoprotem enπched in astrocytes 15 DED,TM=M„ 1 27, 11 15 440820, AL031846, Hs 356416, plakophilin 4, none.none, 1 26, 1065 448153, Y10805, Hs 20521, HMT1 (hnRNP methyltransferase, S cerevi, NuεG SS=M, 1 25, 1207 447386, NMJ06289, Hε 375001, KIAA1027 protein Band_41,l_LWEQ Apolιpoproteιn,IRS,SS=M, 1 22, 1065
433053, BE301909, Hs 279952 glutathione S-transferaεe subunit 13 hom, HCCA_ιsomerase,TM= , 1 20, 1578 440708, AF038962, Hs 7381, voltage-dependent amon channel 3, Euk_poπn,Enterotoxιn_A,PH04,none, 1 20, 1406
417069, AA442192, Hs 374980 cytxhromec oxidase subunit VIII, COX8,SHMT,MIF,GST_C,EF1G domam.GST N,S1,Fz,Fπzzled,calretιculm,7tra 2,rrm PAP assoc,TM=Y,SS=M 1 18, 1691 402559, , , Rho GTPase activating protein 1, PAP2,TM=Y,SS=M 1 16, 1549
426636, BE242634, Hs 2055, ubiquitin xtivating enzyme E1 (A1S9T an, ThιF,UBACT,TM=M„ 1 14, 1099 428773, BE256238, Hs 193163, bridging integrator 1, BAR SH3 SS=M, 1 14, 11 38 406906, Z25424, , gb H sapiens protein seπne/threoπme ki, none.none, 1 13, 1297 443932, AW888222, Hs 9973, tensin, SH2,WW,PID,none, 1 07, 1541 421996, AW583807, Hε 1460, glucagon hormone2,SS=M, 5935, 1 61
414998, NM_002543, Hs 77729, oxidised low density lipoprotem (lectin, lectιn_c,TM=Y,SS=M, 2296, 457 442573, H93366 Hs 7567, branched chain amiπotransferase 1, cytos, amιnotran_4,none, 21 41, 1 15 451035, AU076785, Hs 430, plastiπ 1 (I isoform), efhand.CH Adaptιn_N,SS=M, 1925, 353 408243, Y00787, Hs 624, interieukin 8, HLH,PAS,IL8,TM=M , 1553, 434 421340, F07783, Hs 1369, decay xcelerating factor for complement, sushι,SS=M, 1484, 1959
422260, AA315993, Hs 105484, regenerating gene type IV, lectιn_c,SS=M, 1471, 289 430280, AA361258, Hs 237868, interleukin 7 receptor, fn3,none, 1428, 11 47 412116, AW402166, Hs 784 Epstem-Barr virus induced gene 2 (lymph, 7tm_1,TM=Y,SS=M, 1271, 1256 451820, AW058357, Hs 199248, ESTε, 7tm 1,TM=Y,SS=M, 10 18, 267 418693, AI750878, Hs 87409 thrombospondm 1, EGF,tsp_1,vwc,TSPN,tsp_3,SS=M, 972, 694
448105 AW591433 Hε 298241, Tranεmembrane protease, serine 3, ldl_recepLa,trypsιn,TM=Y,SS=M, 967, 406 456266, L29073, Hs 198726 cold shxk domain protein A, 7tm_2,HRM,CSD,TM=Y,SS=M, 962, 236 413095 AA494359, Hs 30715, potassium voltage gated channel, Isk-rel, none.START, 9 15, 2 18 417933, X02308, Hε 82962, thymidylate synthetase, thymιdylaLεynt,MR_MLE,MR_MLE_N,SS=M, 897, 501 433334, AI927208, Hs 231958, matrix metalloprotemase 28, Peptιdase.M10,none, 871, 428
418030, BE207573, Hε 83321, neuromedin B, Bombesm,TM=M,SS=Y, 8 38, 1 55 433437, U20536, Hs 3280, caspase 6, apoptosis-related cysteine pr, ICE_p10,ICE_p20 SS=M, 831, 423 449523, NM.000579, Hs 54443, chemokine (C-C motif) rxeptor 5, 7tm_1,TM=Y,SS=M, 826, 549 428513, BE220806, Hs 184697, Homo sapiens clone 23785 mRNA sequence, PSI.πone, 8 13, 1328 449444, AW818436, Hs 351306, solute earner family 16 (monxarboxylic, none,TM=Y,SS=M, 789, 700 453459, BE047032, Hs 257789, ESTs, none.none, 740, 060
436729, BE621807, Hs 351316, transmembrane 4 superfamily member 1, none,TM=Y,SS=M, 729, 578 426761, AI015709, Hs 172089 PORIMIN Pro-oncosis rxeptor inducing me, noπe,TM=Y,SS=M, 725, 722
426158, NM 001982, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Fuπn lιke,pkιnase,Rxep_L_domaιn,Fuπn lιke,pkιnase,Recep L_domam,Peptιdase_M24, 7 13, 3 97 419968, X04430, Hs 93913, interieukin 6 (interferon, beta 2), IL6,SS=Y, 693, 343
457133, M54968, Hs 351221, v-Ki ras2Kιrεten ratεarcoma 2 viral on, ras,ldh,SS=M 690, 285 420344, BE463721, Hs 97101, putative G protein-coupled rxeptoπ Methyltraπsf_5,TM=Y,SS=M, 688, 3 10 417874, BE616160, Hs 82829 protein tyrosine phosphatase, non-recept, Y_phoεphatase,TM=Y„ 642, 226 427969, NM.001963, Hs 2230, epidermal growth fxtor (beta-urogastron, EGF,ldl_rxept_b,EB,TM=M,SS=M, 6 37, 1 07 430396, D49742, Hε 241363, hyaluronan-bindmg protein 2, ank,death,ZU5,EGF,kππgle,trypsιn,Nebulιn,LIM,SS=M, 577, 1 24
427557, NM.002659, Hs 179657, plasminogen xtivator, urokmase rxepto, UPAR_LY6,ET,PLA2.ιnh,SS=M, 571, 383 418283, S79895, Hs 83942, cathepsin K (pycnodysoεtoεiε), Peptιdase_C1,SS=M, 559, 3868 458471, AV648609, Hs 194240, ESTs, none.none, 523, 1 05
433470, AW960564, Hs 351316, transmembrane 4 superfamily member 1, πone,TM=Y,SS=M, 488, 460 433293, AF007835, Hε 32417, hypothetical protein MGC4309, none,TM=M„ 456, 496
410867, X63556, Hε 750, fibπllin 1 (Marfan syndrome), EGF,TB,wnt,EB,TIL,SS=M, 432, 2687 417512, X76534, Hs 82226, glycoprotein (transmembrane) nmb, PKD,TM=Y,SS=M, 426, 904
414825, X06370, Hε 77432, epidermal growth fxtor rxeptor (avian , Fuπn-lιke,pkιnase,Rxep_L_domaιn,TM=M,SS=M, 394, 1 16
439180, AI393742, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Fuπn lιke,pkιnase,Rxep_L_domaιn,Fuπn lιke,pkmaεe,Rxep L_domaιn,Peptιdaεe_M24, 376, 221 419508, AW997938, Hs 90786, ATP-b ding cassette, sub-family C (CFTR, ABC_tran,ABC_membrane,TM=Y,SS=M, 347, 224
419749, X73608, Hs 93029, sparc/osteonxtm, cwcv and kazal like d, kazal,thyroglobulιn_1,SS=M, 337, 7 10 436576, AI458213, Hs 77542, ESTs, 7tm 1,DnaJ, 3 15, 3 27 428093, AW594506, Hs 104830, ESTs, none.none, 281, 340
459683, AI674906, Hs 199460, gb wc73f02 x1 NCI.CGAP.Pan1 Homo sapiens, none,TM=Y„ 277, 1 36 414443, AU077268, Hs 76144, platelet-derived growth fxtor receptor,, ιg,pkιnase,TM=Y„ 271, 1053
430451, AA836472, Hε 297939, cathepsin B, Peptιdase_C1,pro_ιsomerase,SS=M, 228, 1459
428953, AA306610, Hs 348183, tumor nxrosis fxtor rxeptor superfami, 60s_nbosomai,Rιbosomal_L10,TNFR c6,DEAD„ 221, 633 435496, AW840171, Hε 265398, PAR-6 beta, none.none, 2 17, 200
418641, BE243136, Hs 86947, a disintegnn and metalloproteinase doma, dιsιntegπn,Reprolyειn,Pep_M12B.propep,EGF,TM=Y,SS=M, 1 91, 1306 414521, D28124, Hs 76307, neuroblastoma, suppresεion of tu oπgeni, DAN,TM=M,SS=M, 1 81, 2229 419452, U33635, Hε 90572, PTK7 protein tyrosine kinase 7, ιg,pkιnase,TM=Y,SS=M, 1 52, 840 452795, AW392555, Hs 18878, hypothetical protein FLJ21620, 20G-Fell Oxy,TM=M„ 1 49, 329 432199, AI693815, Hs 127179, cryptic gene, none,TM=M,SS=M, 1 23, 1 60 453966, BE148734, Hs 63325, transmembrane protease, serine 4, trypsin.ldl rxept.a.none, 1 00, 3 92 445418, AW139377, Hs 127179, cryptic gene, none.none, 1 00, 245
451106, BE382701, Hs 25960, N MYConcogene, HLH.Myc.N term,TM=M„ 1 00, 1 87 447993, AW139525, Hs 170362, ESTs, none.none, 1 00, 1 30
TABLE 42B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Acceεεion Genbank accession numbers Pkey CAT Number Acceεsion
406685 0_0 M18728 414087 1632850.1 W19712 BE247277 400151 9575 21 BC006850 U07418 NM.000249 U07343 AL574783 BI090482 BG684481 AA385302 BG196167 BI091720 BG195132 AI680106 AI457552 AA402478
BG249688 AA347119 BG755996 BG822578
418546 242836.1 T59708 AA224827 T59843 BE156903
TABLE 42C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al ' refers to the publication entitled "The DNA sequence of human chro oεome 22 " Dunham I etal , Nature (1999) 402489495 Strand Indicates DNA strand from which exonε were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 406399 9256288 Minus 6344863554
405102 8076881 Minus 120922-121296
403344 8569726 Plus 7082370990
405555 1552511 Plus 153405-153564,154623-154876,155272-15540
405556 1552511 Plus 163497-163623,164715-164968,16536916550 405204 7230116 Plus 126569-126754
406366 9256126 Minus 10639-10800,10890-11023,11113-11293
400539 7574902 Pluε 85598721
403208 7630829 Minus 147706-147903148667-148804
405203 7230116 Plus 125295-125463 402705 8782736 Plus 89961-90114,90773-90895,91131-91261
402575 9884830 Minus 109742-109883
402559 9864273 Plus 33539-33715
TABLE 43A 43 genes upregulated in pancreatic cancer relative to normal body tissues
Table 43A lists about 43 genes upregulated in pancreatic cancer relative to normal body tissues that are likely to encode proteins particularly useful for diagnostic or prognostic applications These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expression data for exh probeset obtained from this analysiε was expresεed aε average intensity (Al), a normalized value reflxting the relative level of mRNA expression The protein products of these genes often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molecules, peptides, or antibodies (e g pkinase, death-domain, 7tm, phosphatase, or lon.transporter) Certain predicted protein domains are noted
Pkey Unique Eos probeεet identifier number
ExAccn Exemplar xcession number, GenBank a∞esεion number
UniGenelD UniGene number
Pred Prot Domainε Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280) UniGene Title UniGene gene title
R1 90th percentile of pancreatic cancer Als divided by the 50th percentile of normal tisεue Als
R2 90th percentile of pancreatic cancer Alε divided by the 90th percentile of normal paπcreaε Alε, where the 15th percentile of all normal tissue Als was subtrxted from both the numerator and denominator Pkey, ExAccn, UnigenelD, Unigene Title, Pred ProLDomainε, R1, R2
446619, AU076643, Hε 313, sxreted phoεphopratem 1 (osteopontin, , Osteopontm,SS=M, 4495, 217 421552, AF026692, Hs 105700, sxreted fnzzled-related protein 4, Fz,NTR,SS=M, 3540, 2913 411274, NM.002776, Hs 69423, kallikrein 10, trypsιn,TM=M„ 3010, 1359 446921, AB012113, Hs 16530, small inducible cytokine subfamily A (Cy, IL8,SS=Y, 2933, 1608
413719, BE439580, Hs 75498, small inducible cytokine subfamily A (Cy, IL8,SS=M, 2464, 721 452281, T93500, Hs 28792, Homo sapiens cDNA FU11041 fis, clone PL, TGFb_propeptιde,TGF-beta,πone, 2381, 1074 407811 , AW190902, Hs 40098, cysteine knot superfamily 1 , BMP antagon, TGF-beta,DAN,SS=Y, 2233, 1020 404682, , , C9001188* gι|12738842|ref|NP_073725 1| p, none,TM=M„ 1772, 1 40 413554, AA319146, Hs 75426, sxretogranm II (chromogranm C), Granιn,TM=M,SS=Y, 1736, 201
428392, H10233, Hε 2265, εxretory granule, neuroendxnne protei, none,TM=M,SS=M, 1682, 1 70 408243, Y00787, Hs 624, interieukin 8, HLH,PAS,IL8,TM=M„ 1553, 434 419216, AU076718, Hs 164021, small inducible cytokine subfamily B (Cy, IL8,SS=M, 1540, 370 428242, H55709, Hs 2250, leukemia inhibitory fxtor (cholinergic , LIF_OSM,SS=M, 1485, 658 421340, F07783, Hs 1369, dxay xcelerating fxtor for complement, sushι,SS=M, 1484, 1959
409757, NM_001898, Hs 123114, cystatin SN, cyεtatιn,SS=M, 1461, 1275
425071, NM.013989, Hε 154424, deiodmase, lodothyronine, type II, T4_deιodιnase,TM=M,SS=Y, 1435, 1722 414812, X72755, Hs 77367, monokine induced by gamma interferon, IL8,TM=M,SS=Y, 1381, 769 409420, Z15008, Hs 54451, laminin, gamma 2 (nicem (100kD), kalini, lamιnιn_B,lamιπιn EGF,SS=M, 1305, 772 432596, AJ224741, Hs 278461, matπlm 3, EGF,vwa,SS=M, 1280, 991
422109, S73265, Hs 1473, gastπn-releasing peptide, Bombesιn,Defensm_propep,TM=M,SS=M, 1279, 469 421379, Y15221, Hs 103982, small inducible cytokine subfamily B (Cy, IL8,TM=M,SS=Y, 11 36, 222 429547, AW009166, Hs 99376, FGENESH predicted novel sxreted protein, none.none, 1025, 562 422424, AH 86431, Hs 296638, prostate differentiation fxtoπ TGF-beta,SS=M, 996, 1 88 428505, AL035461 Hs 2281 , chromogranm B (secretogranin 1), Granιn,SS=M, 940, 346
409956, AW103364, Hε 727, inhibin, beta A (activin A activin AB a, TGF-beta TGFb propeptιde,Tub,SS=M, 9 19, 1646
418030, BE207573, Hε 83321, πeuromedm B, Bombeειn,TM=M,SS=Y, 838, 1 55
452401 , NM.007115, Hs 29352, tumor nxrosis factor, alpha induced pro, Xlιnk,CUB,SS=M, 746, 496 421582, AI910275, Hs 350470, trefoil factor 1 (breast cancer, estroge, trefoιl,Gastπn,SS=M, 708, 21 61
423634, AW959908, Hs 1690, hepaπn binding growth fxtor binding pr, none,TM=M,SS=M, 678, 12 19
428486, AW583497, Hs 184604 pancreatic polypeptide, hormone3,TM=M,SS=Y, 629, 351
443646, AI085198, Hs 164226, ESTs, EGF,tsp_1,vwc,TSPN,lsp_3,none, 6 17, 4 25
457489, AI693815, Hs 127179, cryptic gene, none,TM=M SS=M, 5 19, 279
450983, AA305384, Hs 25740, ER01 (S cerevιsιae)-lιke, none,SS=M, 501, 743
422867, L32137, Hs 1584, cartilage oligomeπc matrix protein (pse, tsp_3,EGF,SS=M, 487, 940
426322, J05068, Hs 2012, transcobalamin I (vitamin B12 binding pr, Cobalamιn_bιnd,SS=M, 471 , 11 74
414774, X02419, Hs 77274, plasminogen activator, urokmase, kπngle,trypsιn,planLthιonιns,SS=M, 424, 691
428758, AA433988, Hs 98502, CA125 antigen, mucin 16, SEA,TM=Y„ 3 52, 8 43
422048, NM.012445, Hs 288126, spondin 2, extracellular matrix protein, tεp_1,TM=M,SS=M, 345, 769
424687, J05070 Hε 151738, matrix metalloproteinase 9 (gelatmase B, fn2,hemopexιn,Peptιdase_M10,SS=M, 343, 1037
417931, W95642, Hs 82961, trefoil factor 3 (intestinal), trefoιl,SS=M, 298, 9 65
445417, AK001058, Hs 12680, Homo sapiens cDNA FLJ10196 fis, clone HE, tsp_1,Reprolysιn,Pep_M12B_propep,none, 297, 574
432874, W94322, Hs 279651, melanoma inhibitory activity, SH3,TM=M,SS=Y, 2 80, 1053
431462, AW583672, Hs 256311, granin-like neuroendxπne peptide precu, none.none, 270, 1 99
TABLE 43C
Pkey Unique number corresponding to an Eos probeset Ref Sequence source The 7 digit numberε in thiε column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of numan chromosome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA εtrand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLpoεition 404682 9797231 Minus 40977-41150
TABLE 44A 754 GENES UP-REGULATED IN RHEUMATOID ARTHRITIS COMPARED TO NORMAL BODY
Table 44A lists about 754 genes up-regulated in rheumatoid arthritis These were selected from 35403 probeεetε on the Affymetπx/Eoε Hu01 GeneChip
Pkey Unique Eoε probeεet identifier number
ExAccn Exemplar Accession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
Pkey ExAccn UnigenelD Unigene Title
100042 M10098 AFFX control - HUMRGE/M10098.3
101577 M34353 Hs 1041 v-ros avian UR2 sarcoma viruε oncogene h
103353 X89399 Hs 119274 RAS p21 protein xtivator (GTPase xtiva
104743 AA021157 Hs 33619 Homo sapienε cDNA FLJ20096 fiε, clone CO
104996 AA112307 Hs 105894 hypothetical protein FU21919
105437 AA252191 Hs 25199 hypothetical protein
108258 AA063269 gb zm02a09 ε1 Stratagene corneal εtroma
109086 AA166695 Hs 270737 tumor nxrosis fxtor (ligand) superfami
109279 AA196625 Hs 86080 ESTs
109779 F10527 Hs 3353 beta-1,3-glucuroπyltransferase 1 (glucur
111794 R32647 Hs 23545 ESTs
112531 R69798 Hs 29036 ESTε
112784 R96306 Hs 191290 ESTε
113293 T67026 Hs 187403 ESTs
115416 AA283893 Hs 337079 ESTs
116548 D20433 gb HUMGS01407 Human promyelxyte Homo εa
116565 D45533 Hs 129691 hypothetical protein FLJ21603
118104 N55332 Hs 39785 ESTε
119243 T12603 gb CHR90123 Chromosome 9 exon II Homo sa
119336 T55340 Hs 208238 ESTs
120101 W95414 Hs 55497 EST
120715 AA292700 gb zs59a06 ε1 NCI CGAP GCB1 Homo εapiens
120872 AA357993 Hs 96996 ESTs
121010 AA398355 Hs 97330 ESTs
121509 AA412092 Hs 97888 ESTs
121722 AA419482 Hs 98874 similar to proline-πch protein 48
122265 AA436838 Hs 98906 EST
123206 AA489681 Hs 102248 Homo sapiens cDNA FU22105 fiε, clone H
123490 AA599723 gb ag11c07 ε1 Geεεler Wilms tumor Homo s
124198 H53099 Hs 198271 NADH dehydrogenase (ubiqumone) 1 alpha
124294 H90573 Hs 102298 EST
125067 T86429 Hs 111725 ESTε
125153 W38294
125330 AA401804 Hs 114574 ESTε
125335 T86620 Hs 16230 hypothetical protein FLJ20619
125361 T90348 Hs 183404 ESTs
125439 AA826305 gb PM0-LT0017-031299 001-C07 LT0017 Homo
125535 R17430 Hs 22215 secretogramn III
125583 R22272 Hs 86022 ESTs
125590 R23858 Hs 143375 Homo sapiens, clone IMAGE 3840937, mRNA,
125742 H81181 Hs 261023 hypothetical protein FLJ20958 125795 T98190 Hs7756 proteasome (prosome, macropain) 26S subu
125858 H11549 Hs31066 ESTε
125865 H12876 Hs 283078 hOAT4
126039 AA160575 Hs 181102 p30 DBC protein
126143 N29315 Hs266331 hypothetical protein MGC4595
126177 H93164 Hs 129750 hypothetical protein FLJ 10546
126219 N36368 Hs 293483 ESTε, Weakly similar to similar to C el
126221 AI248169 Hs 172965 ESTε
126262 C75147 Hs 143764 ESTs, Weakly similar to unknown [H sapi
126277 N39132 Hs 15441 Crm (Cramped Drosophιla)-lιke
126292 AA491328 gb aa65d09 r1 NCI_CGAP_GCB1 Homo sapiens
126293 Z18870 Hs248121 G protein coupled receptor 22
126353 AI243114 Hs 94031 ESTs
126556 AA491325 Hs 112227 membrane-assxiated nucleic xid binding
126559 R15866 Hs 170263 tumor protein p53 binding protein, 1
126609 W87435 Hs 186802 ESTs
126616 AA348581 Hs 134605 ESTs
126628 AI357886 Hs 170994 hypothetical protein MGC10946
126636 AA001527 gb Zf56g09 r1 Soares retina N2b4HR Homo
126861 AA742428 Hs 144432 ESTs
126990 AA215510 Hs 191650 ESTs
127017 AA740146 Hs251946 poly(A)-bιπdιng protein, cytoplasmic 1-1
127049 AA235966 Hs 291811 ESTs
127209 AA305023 Hs 81964 SEC24 (S cerevisiae) related gene famil
127331 F20186 gb HSPD05873 HM3 Homo εapieπs cDNA clone
127357 AA452788 gb zv80d10 rl Soares_total_fetus_Nb2HF8_
127368 AA434362 Hs 193326 fibroblast growth factor receptor-like 1
127374 AA448728 Hs 312110 ESTs, Weakly similar to I38022 hypothet
127429 AA961490 Hs 293751 ESTs, Moderately similar to TPTE_HUMAN P
127490 W52891 Hs7278 cryptochrome 2 (photolyase like)
127502 AA614422 Hs 183502 ESTs
127647 AI087279 Hs 148410 ESTs
127650 AA873776 Hs 261957 ESTs
127676 D31237 Hs 279938 HSPC067 protein
127746 AI239495 Hs 120189 ESTε
127812 AA749094 Hs 291434 ESTs
127824 AI208365 Hs 127811 ESTs
127933 AA811102 Hs 303581 ESTs, Moderately similar to ALULHUMAN A
128006 AA058693 Hs 129908 KIAA0591 protein
128011 AI347067 Hs 124636 ESTε
128038 AA868782 Hs 137024 ESTs
128058 AI126617 Hs132449 ESTs
128199 AI073548 Hs 164597 ESTs
128308 AI079496 Hs 134169 ESTs
128389 AI142639 Hs 146662 ESTs
128410 AA452788 gb zv80d10 r1 Soares_total_fetus_Nb2HF8_
129199 H90914 Hε 200332 hypothetical protein FU20651
130998 C00810 Hs 293981 guanine nucleotide binding protein (G pr
134409 AA281600 Hs 164915 small nuclear RNA xtivat g complex, p
134578 AA194724 Hs 224137 hypothetical protein
134644 S83308 Hs 87224 SRY (εex determining region Y) box 5
100262 D38500 Hs278468 postmeiotic segregation increased 2-lιke
100676 HG3044-HT3742 Hs 287820 fibronxtin 1
100704 HG3242-HT3419 Hs 166110 calcium channel, voltage-dependent, alph
100787 HG3872-HT4142 Hs302063 immunoglobulin heavy constant mu
100873 HG4333-HT4603 Hs 17364 zinc finger protein 79 (pT7)
100943 HG880-HT880 gb PM0-SN0019-280300-001-D11 SN0019 Homo
100996 J03909 Hs 14623 interferon, gamma-inducible protein 30
101046 K01160
101371 M13232 Hs 36989 coagulation fxtor VII (εerum prothrombi
101461 M22430 Hs 76422 phospholipase A2, group HA (platelets,
101697 M64358 gb Human rhom-3 gene, exon
101909 S69265
102199 U21128 Hs 79914 lumican
102275 U30998 Hs17752 phosphatidylseπne-spxific phospholipas
102295 U32581 Hs 168052 KIAA0421 protein
102319 U34587 Hs 66578 corticotropin releasing hormone rxeptor
102383 U40622 Hs 150930 X-ray repair complementing defxtive rep
102470 U49835 Hs 154138 chitmase 3-lιke 2
102544 U57721 Hs 169139 kynurenmase (L-kynurenine hydrolase)
102649 U68133 gb U68133 Human cell line PCI-06A Homo s
102798 U88898 gb Human endogenous retrovirus H proteas
102804 U89942 Hs 83354 lysyl oxidase-like 2
102851 V00532 Hs 93907 interferon, alpha 14
102852 V00571 Hs75294 corticotropin releasing hormone
102860 X00368 gb Human prolactin gene 5' region
103262 X78565 Hs 289114 hexabrxhion (tenascm C, cytotacliπ)
103484 Y08374 Hs 75184 chitmase 3-lιke 1 (cartilage glycoprote
103559 Z19585 Hs 75774 thrombospondm 4
103658 Z74615 Hs 172928 collagen, type I, alpha 1
103719 AA054109 Hs 4273 hypothetical protein FLJ13159
103876 AA226865 Hs8203 endomembrane protein emp70 precursor iso
103897 AA248870 Hs 55058 EH-domaiπ containing 4 103906 AA249437 Hs 317403 hypothetical protein MGC2744
103985 AA313880 Hs 99872 fetal Alzheimer antigen
104056 AA397529 Hs 58297 CLLL8 protein
104209 AB000221 Hs 16530 εmall inducible cytokine εubfamily A (Cy
104386 H41895 Hs 144164 ESTs, Moderately similar to ALU8_HUMAN A
104398 H53555 Hs 36790 ESTs, Weakly similar to putative p150 [H
104422 H86858 Hs 132909 ESTs
104561 R60100 Hs 323817 DKFZP547E1010 protein
104593 R81267 Hs 98640 hypothetical protein FLJ21069
104643 AA004701 Hs 18978 Homo sapiens cDNA FU22822 fis, clone K
104673 AA007633 Hs 20010 ESTs
104681 AA009832 Hs 34500 ESTs
104711 AA017254 Hs 32794 ESTs
104812 AA034111 Hs 124187 ESTs
104877 AA047437 Hs 22968 Homo sapiens clone IMAGE 451939, mRNA se
104886 AA053348 Hs 339699 growth differentiation factor 11
104924 AA058532 Hs 28774 ESTs, Weakly similar to I38022 hypotheti
105071 AA136532 Hs 29475 ESTs
105105 AA151872 Hs 87016 hypothetical protein FLJ22938
105203 AA195660 Hs 7882 ESTs
105317 AA233926 Hε 52620 integnn, beta 8
105617 AA280687 Hs 4069 glucxorticoid modulatory element bindin
105707 AA291012 Hs 37617 ESTs, Weakly similar to A53933 myosin 1
105754 AA302657 Hs 192028 ESTs
105770 AA347964 Hs 269873 Homo sapiens clone IMAGE 297403, mRNA se
105882 AA400292 Hs 81988 disabled (Drosophila) homolog 2 (mitogen
105883 AA400490 Hs 334907 Homo sapiens, clone MGC 17333, mRNA, com
105890 AA400766 Hs 30512 Homo sapiens mRNA for KIAA0556 protein,
106080 AA418046 Hs 35124 ESTs
106090 AA418909 Hs 169333 hypothetical protein DKFZp761E2110
106096 AA419609 Hs 170121 protein tyrosine phosphatase, rxeptor t
106124 AA423987 Hs 7567 Homo sapiens cDNA FLJ21962 fis, clone H
106308 AA436186 Hs 30662 ESTs
106438 AA449199 Hs 21342 ESTε
106660 AA460936 Hs 27056 KIAA1284 protein
106731 AA465657 Hs 29205 alpha integπn binding protein 63
106880 AA488889 Hs 32425 ESTs
107055 AA600152 Hs 29419 ESTs
107151 AA621169 Hs 8687 ESTs
107183 C20974 Hs 12114 vanin 1
107231 D59299 Hs 34727 ESTs, Moderately similar to I38759 zinc
107490 W74158 Hs 103189 lipopolysxchaπde spxific response-68
107572 AA001903 Hs 59962 ESTs
107620 AA005039 Hs 60171 ESTs
107801 AA019433 Hs 285803 Homo sapiens cDNA FLJ10674 fis, clone NT
107817 AA020781 Hs 60847 ESTs
107823 AA021057 Hs 60836 ESTs
107857 AA024687 Hs 61208 ESTs
107882 AA025630 Hs 231967 ALL1 fused gene from 5q31
108005 AA037769 Hs 194293 ESTs, Weakly εimilar to I54374 gene NF2
108092 AA045961 Hs 184029 hypothetical protein DKFZp761A052
108115 AA047291 Hs 165216 ESTε
108214 AA058661 Hs 60764 ESTε
108382 AA074885 Hs 67726 mxrophage rxeptor with collagenouε εtr
108409 AA075578 gb zm88h03 r1 Stratagene ovanan cancer
108436 AA078801 gb zm94a09 ε1 Stratagene colon HT29 (937
108625 AA101983 Hs 283022 tπggeπng rxeptor expressed on myeloid
108631 AA102553 Hs 334337 ESTs
108763 AA127539 Hs 281397 hypothetical protein AD034
108852 AA133131 gb zm25d03 s1 Stratagene pancreas (93720
108931 AA147186 gb zo38d01 s1 Stratagene endothelial eel
108976 AA151480 Hs 91202 ESTs
109026 AA157811 gb zo35d07 s1 Stratageπe colon (937204)
109170 AA180352 Hs 191472 ESTs, Weakly similar to ALU1 HUMAN ALU
109303 AA206126 Hs 269291 ESTs
109326 AA210719 gb zr88e04 s1 NCI CGAP_GCB1 Homo sapiens
109345 AA213774 Hs 203396 ESTs
109404 AA224594 Hs 86941 ESTs
109473 AA233151 Hs 81796 ESTs
109725 F10003 Hs 79658 casein kinase 1, epsilon
109794 F10684 Hε 23687 ESTs
109835 H00615 Hs 170044 ESTs
109896 H04794 Hs 30489 ESTs
109918 H05641 Hs 216701 Homo sapiens mRNA, cDNA DKFZp564l0816 (f
109950 H08200 Hs 268770 ESTs, Weakly similar to 2004399A chromos
110078 H15054 Hs 318773 KIAA1836 protein
110182 H20402 Hs 31746 hypothetical protein DKFZp547F072
110213 H23216 Hs 86905 ATPase, H+ transporting, lyεosomal (vacu
110310 H38209 Hs 32728 EST
110354 H41280 Hs 22586 ESTε
110413 H48124 Hε 279454 ESTε
110422 H48467 Hε 36094 EST
110433 H49425 Hε 301062 UDP-N acetyl alpha D galactosam e polyp 110434 H49446 Hs 26299 ESTs
110553 H58934 Hs 124990 ESTε
110750 N20522 Hs 30981 ESTε
110827 N30077 Hs 14855 ESTs
110829 N30198 Hs 28625 ESTs
110917 N46363 Hs 5170 ESTs
111100 N62522 Hs 20450 BCM like membrane protein prxursor
111112 N63281 Hs 35452 ESTε
111179 N67239 Hs 10760 aspoπn (LRR class 1)
111185 N67551 Hε 12844 EGF-like-domam, multiple 6
111223 N68921 Hs 334838 KIAA1866 protein
111275 N70970 Hs 35006 ESTs
111443 R01901 gb Homo sapiens endogenous retrovirus W
111573 R10305 Hs 185683 ESTε
111590 R11157 Hs 75425 ubiquitin assxiated protein
111671 R19368 Hs 229084 Homo sapienε cDNA FLJ11666 fis, clone H
111732 R25153 Hs 163813 ESTs
111809 R33616 Hs 24688 EST
111829 R36070 gb Homo sapiens full length insert cDNA
111944 R40606 Hs 21263 suppreεsor of potassium transport defxt
112015 R42836 Hs 23198 ESTs
112023 R43020 Hs 236223 EST
112055 R43621 Hs 26139 ESTs
112334 R56239 Hs 206469 ESTs, Weakly similar to ALU6.HUMAN ALU S
112340 R56602 Hs 8904 Ig εuperfamily protein
112353 R58986 Hs 26613 Homo εapiens mRNA, cDNA DKFZp586F1323 (f
112467 R65706 gb yι16g12 s1 Soareε placenta Nb2HP Homo
112478 R66067 Hs 28664 ESTε
112533 R69886 gb yι47f03 s1 Soares placenta Nb2HP Homo
112588 R77302 gb yι75h08 s1 Soares plxenta Nb2HP Homo
112595, R77783 Hs 22404 protease, serine 12 (neurotrypsin, moto
112676 R86976 Hs 34060 ESTε
112744 R93206 Hs 293762 ESTs, Weakly similar to I38022 hypotheti
112777 R95869 Hs 35467 EST
112817 R98491 Hs 14584 ESTs
112902 T09262 Hs 129190 Human DNA sequence from clone RP5-1046G1
113009 T23699 Hs 7246 ESTs
113151 T51620 Hs 9326 EST
113297 T67161 Hs 13059 ESTs
113398 T82280 Hs 87016 hypothetical protein FLJ22938
113484 T87795 Hs 187543 ESTs
113769 U55966 Hs 22985 alpha2,8-sιalyltranεferase
113794 W37382 Hs 11090 membrane-spanning 4-domaιns, εubfa ily A
113971 W86760 Hs 269172 ESTs
114066 Z38152 Hs 26920 ESTs
114178 Z39063 Hs 17930 chromosome 6 open reading frame 11
114206 Z39294 Hs 27339 EST
114371 Z41835 Hs 27810 ESTs
114428 AA017130 Hs 84790 KIAA0225 protein
114466 AA026970 Hs 135150 lung type-l cell membrane-assxiated gly
114625 AA084362 gb zπ05b10 r1 Stratagene hNT neuron (937
114862 AA235174 Hε 106432 Homo sapiens cDNA FU13410 fiε, clone PL
114908 AA236545 Hs 54973 cadhenn like protein VR20
114973 AA250845 Hs 87762 ESTs
115009 AA251561 Hs 48689 ESTs
115055 AA253005 Hs 61753 ESTs
115098 AA256161 Hs 161729 ESTs
115321 AA280805 Hs 191540 ESTs
115385 AA282540 Hs 109694 KIAA1451 protein
115466 AA287008 Hs 285655 ESTs
115479 AA287596 Hs 278188 ESTs, Moderately similar to I54374 gene
115663 AA405838 Hs 40507 ESTs
115689 AA410645 Hs 199014 ESTs, Moderately similar to ALU7 HUMAN A
115748 AA418835 Hs 90286 ESTs
115810 AA426026 Hs 187615 ESTs
115827 AA427890 Hs 83583 actm related protein 2/3 complex, subun
115881 AA435577 Hs 184942 G protein-coupled receptor 64
116148 AA460708 Hs 62905 hypothetical protein FU14834
116257 AA481493 Hs 88537 ESTs
116365 AA521080 Hs 46765 ESTs
116941 H77395 Hε 39749 ESTs
116982 H81933 Hs 312582 ESTs
116995 H83928 gb ys64b03 ε1 Soares retina N2b4HR Homo
116997 H84214 Hs 40594 ESTs
117016 H87171 Hs 52170 ESTs
117097 H93608 Hs 41919 EST
117101 H94043 Hs 24341 transcriptional co activator with PDZ-bi
117238 N20815 Hs 173337 ESTs
117303 N22776 Hs 264079 ESTs
117399 N26480 Hs 43805 lipoma HMGIC fusion partner-like 3
117503 N31963 Hs 44286 ESTs
117544 N33222 Hs 44451 ESTs
117594 N34929 Hs 171984 ESTs 117627 N36113 Hs 44789 ESTs, Weakly similar to B34087 hypothet
117653 N38970 Hs 194214 ESTs
117695 N40953 Hs 45093 EST
117697 N40976 gb yy80b06 s1 Soares multiple.sclerosis.
117766 N47807 Hs 46767 EST
117807 N48701 Hs 46523 EST
117816 N48872 gb yy77a05 s1 Soares.multiple.scleroεiε.
117882 N50101 Hs 301406 hypothetical protein PP3501
117987 N51935 Hs 47374 Homo εapiens cDNA FLJ13561 fis, clone PL
118074 N54188 Hs 130323 Homo sapiens, clone IMAGE 3960432, mRNA
118114 N56875 Hs 143212 cystatin F (leuk∞ystatm)
118151 N58276 Hs 229119 EST
118270 N62868 Hs 48653 ESTs
118291 N63076 Hs 138746 EST
118358 N64017 Hs 144633 hypothetical protein DKFZp434F2322
118383 N64529 Hs 49001 EST
118412 N64856 Hs 97437 centrosomal protein 1
118433 N66248 Hs 141609 EST
118600 N69222 Hs 238936 ESTs, Weakly similar to (deflme not av
118641 N70298 Hs 49829 ESTs
118643 N70324 Hs 49840 ESTs
118695 N71781 Hs 50081 KIAA1199 protein
118915 N91481 Hs 54713 ESTs
119041 R02591 Hs 284294 Breakpoint cluster region protein, uteπ
119069 R27619 Hs 231046 EST
119105 R42357 Hs 91453 ESTs
119154 R61293 gb yh07a05 s1 Soareε infant brain 1NIB H
119241 T12559 gb CHR90079 Chromosome 9 exon II Homo sa
119269 T16367 Hs 65327 EST
119310 T40427 gb ya01a06 s2 Stratagene lung (937210) H
119345 T63474 Hs 90696 EST
119353 T66867 Hs 187402 ESTs
119390 T89122 Hs 249712 ESTs, Weakly similar to ALU1_HUMAN ALU
119423 T99544 Hs 173734 ESTs, Weakly similar to ALU1 HUMAN ALU
119428 W02129 Hs 55242 EST
119529 W38053
119795 W73370 Hs 339722 ESTs, Highly similar to S03917 fibronec
119817 W74257 Hs 159690 ESTs
119831 W78050 Hs 58419 DKFZP586L2024 protein
119930 W86471 Hs 151624 hypxretin (orexin) rxeptor 2
120039 W92548 Hs 94985 ESTs
120256 AA169801 Hs 98710 hypothetical protein
120284 AA182626 gb zp54e11 s1 Stratagene NT2 neuronal pr
120350 AA211300 Hs 108614 KIAA0627 protein, Droεophila multiple as
120379 AA227849 gb DKFZp434B1822_r1 434 (synonym htes3)
120383 AA228030 Hs 123122 FSH pπmary response (LRPR1, rat) homolo
120420 AA236031 Hs 112885 spinal cord denved growth fxtor-B
120437 AA243427 Hs 104311 novel protein with MAM domain
120461 AA251301 Hs 293369 ESTs
120594 AA282054 Hs 5094 nng finger protein 10
120611 AA284178 Hs 110637 homx box A10
120626 AA285064 Hs 104485 EST
120696 AA291503 Hs 97249 ESTs
120747 AA302976 Hs 96672 ESTs
120749 AA303235 gb EST14544 Testis tumor Homo sapiens cD
120752 AA311972 Hs 22895 hypothetical protein FU23548
120851 AA349662 Hs 174248 ESTs
120866 AA350718 Hε 291272 ESTs
120949 AA397830 Hs 98347 ESTs, Weakly similar to JC5308 testiε-sp
120996 AA398281 Hs 308114 ESTs
121038 AA398536 Hs 97365 ESTs
121065 AA398658 Hs 97300 ESTs
121067 AA398662 Hs 97302 ESTs
121071 AA398678 Hs 139355 ESTs
121082 AA398722 gb zt75h07 s1 Soareε testis NHT Homo sap
121172 AA400013 Hs 97750 EST, Weakly similar to MPL3 RAT MICROTUB
121191 AA400205 Hε 104447 ESTs
121354 AA405384 Hs 193737 ESTs
121393 AA405981 Hs 262643 ESTs
121399 AA406059 Hs 332700 EST
121479 AA411911 Hs 98110 ESTs
121498 AA412033 Hs 178045 ESTs
121704 AA418743 Hs 98306 KIAA1862 protein
121736 AA421131 Hs 148515 Human clone 23564 mRNA sequence
122198 AA435892 Hs 97541 ESTs
122220 AA436011 Hs 98187 ESTs
122250 AA436692 Hs 98892 EST
122279 AA437209 Hε 234016 ESTs
122286 AA437259 Hs 104944 ESTs
122330 AA442870 Hs 98628 Homo sapiens, clone IMAGE 4214491, mRNA,
122338 AA443311 Hs 98998 ESTs
122355 AA443789 Hs 19978 CGI-30 protein
122590 AA453264 Hs 99310 ESTs 122746 AA458791 gb aa88c02 s1 Stratagene fetal retina 93
122805 AA460702 Hs 82772 collagen type XI, alpha 1
122841 AA461536 Hs 288908 WAS protein family, member 2
122899 AA469960 Hs 178420 ESTs, Highly similar to WASP interacting
122933 AA476728 Hs 107537 chromosome 7 open reading frame 2
123005 AA479726 Hs 52620 integnn, beta 8
123142 AA487504 Hs 105718 EST
123153 AA488349 Hs 334808 hypothetical protein MGC4189
123168 AA488881 Hs 105218 EST
123188 AA489092 Hs 177726 ESTs
123276 AA491270 Hs 187946 ESTs
123305 AA496133 gb zv51e12 s1 Soareε.teεtis.NHT Homo sap
123328 AA496S68 gb aa42g03 s1 Soares.NhHMPu.S1 Homo sapi
123450 AA598913 Hs 111207 ESTs
123464 AA599014 Hs 153321 Homo sapiens cDNA FLJ 10577 fis, clone NT
123650 AA609332 Hs 180696 ESTε
123700 AA609606 Hs 191956 ESTε
123858 AA620821 Hs 112911 EST
123863 AA620873 Hs 112916 ESTε
124046 F10243 gb HSC3CC122 normalized infant brain cDN
124059 F13673 Hs 283713 ESTs, Weakly similar to S64054 hypotheti
124196 H52617 Hs 144167 ESTs
124197 H52921 gb yq76c09 s1 Soareε fetal liver spleen
124229 H62793 Hs 268945 ESTs
124230 H63111 Hs 6655 Homo sapienε EST from clone 208499, full
124241 H65947 Hs 165355 ESTε, Moderately similar to ZN91.HUMAN Z
124251 H68286 Hs 107924 ESTs
124400 N30597 Hs 179152 toll like receptor 7
124416 N34042 Hs 271674 ESTs
124570 N67117 Hs 102808 ESTs
124575 N68168 gb za11c01 ε1 Soares fetal liver spleen
124588 N69197 Hs 191361 ESTs, Weakly similar to I38022 hypotheti
124598 N70294 Hs 269137 ESTs, Weakly similar to A56194 thromboxa
124655 N93176 Hs 102914 ESTs
124706 R07499 Hs 193612 ESTs, Weakly similar to ALU8_HUMAN ALU
124848 R60135 Hs 203498 EST
124882 R74041 Hs 101539 ESTs
124898 R82846 Hs 273789 ESTs
125086 T91161 Hs 173880 interleukin 1 rxeptor accessory protein
125145 W38001
125216 W73409 Hs 103185 ESTs
125342 AI055916 Hs 133552 ESTs
125351 T96520 Hs 324746 alpha-2-HS-glycoproteιn
125419 AI076822 Hs 134544 ESTs
125424 T99667 Hs 18564 ESTs
125526 R14487 Hs 17110 Homo sapiens mRNA, cDNA DKFZp434C2016 (f
125539 R17870 Hs 248120 G protein-coupled rxeptor 21
125633 AA908225 Hs 15463 Homo sapiens, clone IMAGE 2959994, mRNA
125689 R48940 Hs 108043 Fπend leukemia virus integration 1
125707 C14616 Hs 284122 Wnt inhibitory factor-1
125790 AA868325 Hs 99962 proteoglycan 2, bone marrow (natural kil
125876 AA324967 Hs7298 biphenyl hydrolase-like (seπne hydrolas
125969 R94247 Hs 88414 BTB and CNC homology 1, basic leucine zi
125970 A1400964 Hs 177516 high density lipoprotein binding protein
125975 AA495891 Hε 152290 ESTε, Highly similar to JC2463 vasoaotiv
125985 H54857 Hs 35981 ESTs
126018 H54866 Hs 167583 ESTs
126032 H59735 Hs 269065 ESTs, Highly similar to KIAA0349 [H sapi
126059 H66582 Hs 308486 ESTs
126107 H79155 Hs93361 ESTs
126154 AI004105 Hs 190488 Homo sapiens, Similar to nuclear l∞aliz
126199 AI000492 Hs 125829 ESTs
126207 W77936 Hs 83583 xtin related protein 2/3 complex, subuπ
126227 N27236 Hs 269034 ESTε
126269 AA830432 Hε 44701 ESTs
126373 F11606 Hε6079 B cell RAG assxiated protein
126378 AA347842 gb yy62a11 s1 Soareε_multιple_εclerosιs
126383 AA885594 Hε6298 KIAA1151 protein
126403 N73388 Hε 125976 ESTs, Weakly similar to S71949 metallopr
126525 AA884833 Hs 166432 ESTs
126527 AA548559 Hs 103853 hypothetical protein FLJ20043
126566 W67245 Hs 103142 ESTs
126583 W92895 Hs 279746 vamlloid receptor-like protein 1
126610 AA460338 Hs 191391 ESTs
126622 AA699443 Hs 193213 ESTs
126633 AA206993 Hs 315367 Homo sapiens, Similar to hypothetical pr
126727 AA037230 Hs 135084 cystatm C (amyloid angiopathy and oereb
126762 AA064671 gb zm13b04 si Stratagene pancreas (93720
126775 S86382 Hε957 putative opioid rxeptor, neuro edin K (
126783 AA126047 gb zn09d10 s1 Stratagene hNT neuron (937
126882 AA761143 Hε 250581 SWI/SNF related, matnx assxiated, xti
126945 R51877 Hs 25845 ESTs
126968 AI311457 Hs 99472 ESTs 127070 AA641812 Hs 190037 ESTs
127087 AA380418 Hs 88012 SHP2 interacting transmembrane adaptor
127187 AA297138 Hs 207422 ESTs, Weakly similar to S71949 metallopr
127215 AI246377 Hs 127675 ceroid lipofuscinosis, neuronal 8 (epile
127229 AA316181 Hs 61635 εix tranεmembrane epithelial antigen of
127278 AA342715 gb EST48309 Fetal εpleen Homo sapiens cD
127299 AA360710 Hs 158480 ESTs
127325 AA393073 Hs 126099 ESTs
127347 AA428350 Hε 58389 hypothetical protein MGC4090
127401 AA921944 Hε 127639 ESTs
127420 AA699582 Hs 82171 Homo sapiens clone 191B7 placenta expres
127438 AI224421 Hs 77100 general transcription factor HE, polype
127441 AA835684 Hs 287601 Homo sapieπε cDNA FLJ13830 fis, clone TH
127449 AI421866 Hs 75722 πbophoπn II
127493 AA808081 Hs 291701 ESTs
127505 AA594244 Hs 292245 ESTs Weakly similar to ALU1 HUMAN ALU S
127620 AI025699 Hs 116200 ESTs
127623 AA773234 Hs 271877 angiopoietm like 2
127633 A1339609 Hs 268538 potassium voltage gated channel, Isk rel
127701 AA935466 gb zf84c06 s1 Soareε pineal jland N3HPG
127713 AA688322 Hs 150683 ESTε
127722 AA700444 Hs 189186 ESTs Weakly similar to ALUD HUMAN ""
127733 AA704680 Hs 189005 ESTs
127816 AA743646 Hs 120604 ESTs, Weakly similarto YA02 HUMAN HYPOT
127966 AI493406 Hs 292514 ESTε
127973 AI336794 Hs 129117 ESTε
127989 AA909267 Hs 132413 ESTs
127997 AI281549 Hε 311054 Homo εapieπs mRNA full length insert cDN
128016 N92597 Hs 82689 tumor rejection antigen (gp96) 1
128037 AA868394 Hs 181129 ESTs Weakly similar to S18968 cyπtesti
128053 T65605 Hs 65377 ESTs Moderately similar to KIAA1399 pro
128066 AA884838 Hs 189171 ESTs
128071 AA889398 Hs 189241 ESTs
128091 AA904559 Hs 129329 ESTs
128113 AI341423 Hs 288433 neurotπmin
128145 AI498467 Hs 166669 solute earner family 4, εodium bicarbon
128167 AA932961 Hs 85752 uπcharacteπzed hematopoietic εtem/proge
128195 AI143866 Hs 127778 ESTε
128265 T95851 Hs 17691 ESTs
128283 AI076570 Hs 134053 ESTs
128309 AI457235 Hs 166479 ESTs
128313 AI051250 Hs 157775 ESTs
128346 AI088907 Hs 160189 ESTs
128359 AI096526 Hs 270244 ESTs Weakly similar to I38022 hypotheti
128369 F12681 Hs 30445 Homo sapienε cDNA FLJ 14687 fiε, clone NT
128371 H12876 Hs 283078 hOAT4
128421 T77876 Hs 268589 ESTε
128453 X02761 Hs 287820 fibronxtin 1
128496 T83496 Hs 32944 mositol polyphosphate-4-phosphataεe, ty
128514 H84261 Hs 301693 Homo εapiens, clone IMAGE 3638994, mRNA,
128551 H09058 Hs 278398 KIAA1117 protein
128683 AA316862 Hs 9605 cleavage and polyadenylation spxific fa
128731 AF005271 Hs 104555 neuropeptide FF amide peptide precursor
128843 AA234141 Hs 275675 katanm p80 (WD40-contaιnιng) subunit B
128988 AA411040 Hs 294140 ESTs
129016 W84524 Hs 184194 transmembrane 4 superfamily member 5
129021 AA426406 Hs 173081 KIAA0530 protein
129095 L12350 Hs 108623 thrombospondm 2
129171 AA234048 Hs 7753 calumenm
129188 M30257 Hε 109225 vascular cell adhesion molxule 1
129410 U25987 Hs 272620 pregnancy spxific beta-1 -glycoprotein 9
129467 AA410311 Hs 44208 hypothetical protein FLJ23153
129518 AA369807 Hs 112238 ESTε
129534 R73640 Hs 11260 hypothetical protein FLJ 11264
129632 L27213 Hs 1176 εolute earner family 4, anion exchanger
129691 X06700 Hs 119571 collagen, type III, alpha 1 (Ehlerε Danl
129881 AA458952 Hs 181406 hypothetical protein FLJ22301
129990 N30316 gb yw75b05 si Soareε_plxenta_8to9weeks_
130049 V01515 Hs 1460 glucagon
130171 AA454177 Hs 245257 ESTs, Weakly similar to A46010 X linked
130411 AA505009 Hs 169910 KIAA0173 gene product
130479 R44163 Hs 12457 hypothetical protein FLJ10814
130511 L32137 Hs 1584 cartilage oligomeπc matnx protein (pse
130521 U92971 Hs 194351 coagulation fxtor II (thrombin) recepto
130645 AA020942 Hs 17200 STAM like protein containing SH3 and ITA
130655 N92934 Hs 17409 cysteine πch protein 1 (intestinal)
130656 Z20481 Hs 330988 Homo sapienε Similar to Bicaudal D (Dro
130889 D57622 Hs 20985 ειn3-assxιated polypeptide 30kD
131064 AA598441 Hs 22583 DKFZP434K2235 protein
131070 F13694 Hs 22607 ESTs
131189 L16782 Hs 240 M phase phosphoprotem 1
131318 X51699 Hs 2558 bone gamma-carboxyglutamate (gla) protei
131506 W47579 Hs 5801 KIAA1194 protein 131551 AA127867 Hs 28608 Homo sapiens cDNA FLJ22115 fis, clone H
131563 C20547 Hs 302810 Novel human gene mapping to chomosome 20
131830 U33054 Hs 32959 G protein-coupled receptor kinase 2 (Dro
131879 AA017161 Hs 33792 ESTs
132017 W67251 Hs 267659 vav 3 oncogene
132025 U58516 Hs 3745 milk fat globule EGF factor 8 protein
132096 AA131410 Hs 3964 Homo sapiens clone 24877 mRNA sequence
132159 D76435 Hs 41154 Zic family member 1 (odd paired Drosophi
132164 U84573 Hs 41270 procollagen-lysine, 2-oxoglutarate 5-dιo
132180 AA405569 Hs 418 fibroblast activation protein, alpha
132223 R77451 Hs 4245 chromosome 11 hypothetical protein ORF3
132238 AA453446 Hs 42673 ESTs
132406 F09979 Hs 4774 Homo sapiens mRNA, cDNA DKFZp761C1712 (f
132945 N40559 Hs 6129 ATP binding cassette, sub-family B (MDR/
133185 AA481404 Hs 6686 hypothetical protein DKFZp56401664
133193 C14015 Hs 303075 EST
133370 AA156897 Hs 72157 DKFZP564I1922 protein
133406 U22172 Hs 179697 Human DNA damage repair and rxombinatio
133409 U65918 Hs 73078 deleted in azoospermia like
133591 T82292 Hs 75111 protease, seπne, 11 (IGF binding)
133899 X00588 Hs 77432 epidermal growth factor receptor (avian
134137 F10045 Hs 79347 KIAA0211 gene product
134339 AA478971 Hs 81988 disabled (Drosophila) homolog 2 (mitogen
134421 AA122386 Hs 82985 collagen, type V, alpha 2
134462 U11037 Hs 181300 sel 1 (suppressor of lιn-12, C elegans)-
134515 C20737 Hs 84469 ESTs
134527 T40835 Hε 322978 EST
134711 X04011 Hs 88974 cytxhrome b 245, beta polypeptide (chro
134824 S78723 Hs 298623 5 hydroxytryptamine (εeroton ) rxeptor
134854 J03464 Hs 179573 collagen, type I, alpha 2
134921 W60186 Hs 125511 Homo sapiens mRNA cDNA DKFZp434P1530 (f
135003 H42527 Hs 26102 tπchorhinophalangeal syndrome I
135210 W90522 Hs 93589 hypothetical protein DKFZp564B1162
135348 AA442054 Hs 268177 phospholipase C, gamma 1 (formerly subty
100547 HG2149 HT2219 gb Homo εapiens mucin (mucin) mRNA, part
100572 HG2271-HT2367 Hs 73995 filaggππ
100687 HG3115-HT3291 gb Human Golli mbp gene, exon 2
100695 HG315-HT315 Hs 272620 pregnancy spxific beta 1-glycoproteιn 9
101447 M21305 gb Human alpha satellite and satellite 3
102329 U35407 Hs 158084 peroxisome receptor 1
102892 X05232 Hs 83326 matnx metalloprote ase 3 (stromelysin
103036 X54925 Hs 83169 matnx metalloprotemase 1 (interstitial
103206 X72755 Hs 77367 monokine induced by gamma interferon
103260 X78416 Hs 3155 casein, alpha
103751 AA082824 gb zo08b08 s1 Stratagene neuroepithelium
104113 AA427510 Hs 181202 hypothetical protein FU 10038
104316 D61871 Hs 330821 EST
104453 M19169 Hs 123114 cystatin SN
104668 AA007312 gb EST376458 MAGE resequences, MAGH Homo
104916 AA056588 Hε 155489 NS1-asεxιated protein 1
106151 AA424958 Hε 294132 ESTε
106899 AA490107 Hs 21753 JM5 protein
107379 U93868 Hs 333861 polymerase (RNA) III (DNA dirxted) (32k
107412 W26105 Hs 287797 integπn, beta 1 (fibronxtin rxeptor,
107652 AA010195 Hε 52642 ESTs, Weakly similar to ALUF HUMAN ""
107754 AA017462 Hε 269244 ESTs
107897 AA026240 gb no77a05 s1 NCI.CGAP.AA1 Homo sapiens
108238 AA059473 Hε 66783 EST
108497 AA083070 gb zm85a05 r1 Stratagene ovanan cancer
108710 AA121960 gb zm24g09 r1 Stratagene pancreas (93720
109012 AA156576 Hε 5947 mel transforming oncogene (deπved from
109043 AA159605 Hs 72580 ESTs
109560 F01778 Hs 131740 Homo sapienε cDNA FLJ22562 fis, clone H
110572 H60523 Hs 37844 EST
110687 H93005 Hs 177311 ESTs
111418 R01084 Hs 19081 ESTs
111507 R07728 Hε 268668 ESTs
111644 R16539 Hs 223649 EST, Moderately similar to Cd-7 Metallo
111919 R39926 Hs 21031 ESTs, Weakly similar to 178885 seπne/th
112102 R44840 Hs 326475 ESTε
112229 R50938 Hs 24949 ESTε
112309 R55021 gb yj76d05 s1 Soares breast 2NbHBst Homo
112368 R59371 Hs 26653 ESTε
112397 R60822 Hs 26805 ESTs, Weakly similar to putative p150 [
112532 R69824 Hs 28313 ESTε
112858 T02963 Hs4454 ESTε
113170 T54342 Hs 270373 ESTε, Weakly similar to S65657 alpha-1 C
113321 T70580 Hs 13759 RAB3A interxtmg protein (rabm3) like
113404 T82323 Hs 70337 immunoglobulin superfamily, member 4
113420 T83964 Hs 15400 ESTs, Weakly similar to S65824 reverse
113613 T93337 Hs 17167 ESTs, Highly similar to LRR FU I mtera
113663 T95909 gb ye47g07 s1 Soares fetal liver spleen
113790 W33178 Hs 26912 ESTs 113889 W72720 gb zd61c03 ε1 Soareε fetal heart_NbHH19W
114016 W90671 Hs 11087 ESTε
114251 Z39898 Hs 21948 ESTε
115187 AA261805 Hs 44021 Homo εapieπε mRNA for FLJ00065 protein,
115722 AA417297 Hs 59609 ESTε
115775 AA424030 Hs 46627 ESTε
116380 AA598455 Hs 66817 ESTε
116551 D20458 Hs 229071 EST
117009 H85422 Hs 108556 ESTε
117329 N23680 Hs 93670 Homo sapiens cDNA FLJ22664 fiε, clone H
117523 N32626 Hs 145532 ESTε, Weakly similar to FV1 MOUSE FRIEND
118387 N64579 gb yz51d11 s1 Morton Fetal Cochlea Homo
118456 N66580 gb yy69f01 s1 Soares.multiple.scleroεiε.
118741 N74042 Hs 50421 KIAA0203 gene product
118771 N74690 Hs 50547 ESTε
119075 R36451 Hs 287820 fibronxtin 1
119217 R95778 Hs 237309 EST
119306 T26914 Hs 132785 EAP30 subunit of ELL complex
119347 T64349 gb yc10d08 s1 Stratagene lung (937210) H
120006 W90108 Hs 10848 KIAA0187 gene product
120441 AA243588 Hs 190035 ESTε
120651 AA287286 Hs 99657 ESTs
120811 AA346854 Hs 52788 fragile X mental retardation, autosomal
121186 AA400156 Hs 339808 hypothetical protein FLJ10120
121599 AA416770 Hε 98255 EST
122146 AA435584 Hε 250173 hypothetical protein FLJ13158
122261 AA436830 Hs 98902 ESTs
122352 AA443725 Hs 159677 ESTs
122433 AA447417 Hs 285491 ESTs
122489 AA448342 Hs 178551 πbosomal protein L8
122554 AA451886 Hs 154654 cytochrome P450 subfamily I (diox ind
122857 AA463879 Hs 99606 EST, Weakly similar to STK2.HUMAN SERIN
122889 AA465704 Hs 287687 Homo sapiens cDNA FLJ21960 fis, clone H
123399 AA521274 Hs 105516 EST
123662 AA609385 Hs 112703 ESTs, Moderately similar to AF171102 1 r
123762 AA610013 gb af18d04 s1 Soares testis NHT Homo sap
123792 AA620333 Hs 112857 ESTs
123900 AA621223 Hs 112953 EST
123981 C20797 Hs 95481 ESTs
124126 H18517 Hs 164568 fibroblast growth fxtor 7 (keratmxyte
124404 N31998 Hs 164256 hypothetical protein FLJ20657
124557 N66025 Hs 141604 ESTs, Moderately similar to ALULHUMAN A
124703 R07294 Hs 300076 solute camerfamily 22 (organic cation
124867 R68971 Hs 168500 ESTs
125092 T92544 H 137548 CD84 antigen (leukocyte antigen)
125111 T96240 Hs 178658 RAD23 (S cerevisiae) homolog B
125331 AI422996 Hs 161378 ESTs
125349 T87826 Hs 164480 ESTs, Weakly similar to T50609 hypotheti
125426 R43963 Hs 184029 hypothetical protein DKFZp761A052
125436 R64472 Hs 16131 hypothetical protein FLJ 12876
125465 AI375276 Hs 158732 ESTs
125515 R13353 gb yf76c04 rl Soares infant brain 1NIB H
125626 AI038854 Hs 180789 S164 protein
125656 AA040118 Hs 78687 neutral sphingomyelinase (N SMase) xtiv
125743 H17151 gb ym37a05 r1 Soares infant brain 1NIB H
125757 AI274906 Hs 166835 ESTs, Highly similar to 1814460A p53-ass
125760 W03020 Hs 40300 calpam 3, (p94)
125804 R79519 " Hs 16899 ESTs
125967 AI341206 Hs 173770 ESTs
126068 AI190171 Hs 144413 ESTs
126081 AI346024 Hs 227835 KIAA1049 protein
126150 AA018427 Hs 64616 chromosome 12 open reading frame 3
126171 AA704771 Hs 191942 ESTs
126198 AI469355 Hs 127310 ESTs
126224 AI097280 Hs 44493 Human DNA sequence from clone 462023 on
126289 AA194603 Hs 73451 ESTs, Weakly similar to S55024 πebulin,
126343 AA628890 Hs 158701 ESTs
126406 AA034096 gb yv41h02 r1 Soares fetal liver spleen
126419 AA451775 Hs 129064 Homo sapiens chromosome 19, cosmid F2216
126479 T78141 Hs 12285 ESTs, Weakly similar to 155214 salivary
126500 AA885306 Hs 184376 synaptosomal-associated protein, 23kD
126520 AA292988 Hs 72071 hypothetical protein FLJ20038
126701 AA515212 Hs 339670 ESTs, Weakly similarto AF1477901 trans
126718 AA322718 Hs 309435 ESTs, Weakly similar to KIAA0927 protein
126739 AI160709 Hs 289047 Homo εapiens cDNA FLJ14059 fis, clone HE
126745 AA057506 gb zf49g04 r1 Soares retina N2b4HR Homo
126846 AA663527 Hs 116910 ESTs
126872 AA136653 gb Ul-H BI3-ala a 120-UI s1 NCI_CGAP.Su
126952 AA195575 Hs 85962 hyaluronan εynthase 3
127036 AI468598 Hs 276916 nuclear rxeptor subfamily 1, group D, m
127039 AA233366 Hs 168103 prp28, U5 εnRNP 100 kd protein
127067 F06732 gb HSC1 JA051 normalized infant brain cDN
127083 Z44079 Hε 91608 otofertin 127116 AA278492 Hs 288304 Homo sapienε cDNA FLJ 11529 fis, clone HE
127282 AA347547 Hs 185780 ESTs
127349 AA412108 Hs 269350 ESTs
127352 AA416577 Hs 189105 ESTs, Weakly similar to NBR13 [H sapienε
127482 AI337294 Hs 105352 GalNAc alpha 2, 6 εialyltransferase I, I
127543 AI364367 Hs 157392 Homo sapiens cDNA FLJ20780 fis, clone CO
127553 AA282433 gb aa63g02 r1 NCI.CGAP.GCB1 Homo sapiens
127556 AA679831 Hs 190228 ESTs
127859 AA806837 Hs 291559 ESTs
127993 AA847856 Hs 124565 ESTs
128277 AI018275 Hs 269791 ESTs
128285 AA634569 Hs 13351 LanC (bacterial lantibiotic synthetase c
128317 AI051960 Hs 303754 ESTs
128334 AI080130 Hs 134207 ESTs
128428 AI185718 Hs 143900 ESTs
128582 U22963 Hs 101840 major histocompalibility complex clasε
128592 AA470056 Hs 113994 Homo εapienε cDNA FLJ20796 fis, clone CO
128751 AA442274 Hs 183176 ESTs
129105 AA224351 Hs 108681 Homo sapienε brain tumor aεεociated prot
129161 N27334 Hs 181780 hypothetical protein FLJ20241
129246 N99174 Hs 206063 ESTε
129361 X64229 Hs 110713 DEK oncogene (DNA binding)
129577 AA424952 Hs 82906 CDC20 (cell diviεion cycle 20, S cerevi
129600 N78980 Hs 271599 hypothetical protein MGC10500
129989 AF005887 Hs 247433 activating transcription factor 6
130024 U15197 Hs 113271 ABO blood group (transferase A, alpha 1-
130292 U70136 Hs 218791 proteoglycan 4, (megakaryxyte εtimulati
130589 AA234308 Hs 16441 DKFZP434H204 protein
130736 T99385 gb ow89g07 ε1 Soareε_fetal liver spleen_
131238 R82327 Hs 24625 ESTs
131378 AA463886 Hs 203910 small glutamine rich tetratπcopeptide r
131601 M31165 Hs 29352 tumor necrosiε factor, alpha-induced pro
131605 AA256220 Hs29383 Homo sapiens mRNA, cDNA DKFZp434E2321 (f
131676 C20785 Hs 30514 ESTs
131861 D11925 Hs 184245 KIAA0929 protein Msx2 inteπacting nuclea
131873 H39997 Hs 166852 KIAA1683 protein
132023 F01927 Hs3743 matnx metalloproteinase 24 (membrane in
132273 AA489716 Hs43658 DKFZP586L151 protein
132770 AA425647 Hs 56406 Homo sapiens cDNA FLJ13549 fis, clone PL
132859 D20925 Hs69235 transportin SR
133052 R40166 Hs 106826 KIAA1696 protein
133373 S72487 Hs73946 endothelial cell growth fxtor 1 (platel
133446 M25322 Hs 73800 selxtm P (granule membrane protein 140
134693 N70361 Hs8854 Human transcnption unit PVT gene, exons
134733 U03644 Hs89421 CBF1 interacting corepresεor
134965 J05480 Hs 272458 protein phosphatase 3 (formerly 2B), cat
135327 AA477989 Hs 98800 ESTs
135377 C21382 Hs99766 Homo sapiens mRNA cDNA DKFZp564J0323 (f
135398 AA194075 Hs 287270 ret proto-oncogene (multiple eπdxπne
TABLE 44B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank xcesεion numbers
Pkey CAT number Accessions 108497 110079_2 AA074897 AA113914 AA064871 AA079329 AA071309 AA084710 AA129030 AA075042 AA074794 AA071453 AA078803 AA148628
AA122204 AA074159 AA126185 AA079117 AA127089 AA070912 AA079280 AA131372AA078833 AA071087 AA076131 AA071047
AA079401 AA083070 AA102076 AA115163 AA074198 AA134725 AA113889 AA121103 AA075041 AA065148AA071310 AA101144
AA079659 AA078931 AA079209 AA070928 AA068994 AA069817 AA076187 AA069053 AA131489 AA071308 AA063317 AA070156
AA071430 AA076056 AA075684 AA070053 AA126283 AA126078 AA075895 AA079208 AA074583 AA071086 AA079623 AA070627
AA078802 AA076622 AA065051 AA079143 AA071110 AA079434 AA148748 AA079230 AA085188 AA074485 AA070580 AA076151
AA083166 AA085118 AA079450 AA085044 AA120938 AA079200 AA100188 AA081472 AA122355 AA129031 AA085362 AA069220
AA070940 AA075968 AA074563 AA084027 AA115929
107897 917761 AA604872 AA026240
130736 6114141 AI168326T99385
108710 1335601 AA121959 AA121960
100943 459761 AW864944 L07517 AW869606
124575 16666491 N68168 N69188 N90450
125439 4655901 AW835829AA826305 R01759
117697 4998771 N40976 AA902795
125515 1812 R13353 R13890 H11359
118387 65081 -5 N64579
126292 3275121 AA491328 N42312
102798 346244 U88896 U88898 AA916056 T03285 AI341594 AI359534 AI634031 U88897
126378 2444441 N58924AA347842
125743 50255 H17151 H11956
126406 957031 N76683 AA034096 AA034082 127067 1534978.1 F06732 Z43705 119243 1774795.1 T12603 T12604 111443 3152818 AF072503 AF208161 AA613238 H12439 N76991 D78692 BE019603 AA776439 R37932 T93615 AF072508 R00744 R01948 R68685
AI128496 AA865193 AI797629 H13302 AF072506 NM_014590 AF072505 R00743 T93661 T39519 R68740 H13097 N58614 N77302
H01372 N41878 H04136 AA426511 AW971553 AW900030 R76136 T52094 AI598135 AA781423 R76086 R77278 AI393478 AA837267
AI570707 R01901 R27412 N53177 AI379210 A1128526 AA250958 R79323 R27389 H01325 N55091 T69704 AA868777 T47345 R27591
AA860368 AA729556 H04137 T87297 C17420 AA293243 AA419144
127278 240640 1 AA342715 AA367634
103751 118557 1 AA131367 AA082824
126636 80804 1 AA057531 AA001527
127331 379388 1 F20186 AA622352
127357 288073 1 AA424107 AA452788
126745 104479 1 AA047854 AA057506 AA053841
126762 110350 1 AA064613 AA064671
126783 113388 1 AA083531 AA126047 AA074915 AA148649
112309 1576900 1 R55021 H26613
126872 142696.1 AW450979 AA136653 AA136656 AW419381 AA984358 AA492073 BE168945 AA809054 AW238038 BE011212 BE011359 BE011367
BE011368 BE011362 BE011215 BE011365 BE011363
120284 158963 1 AA179656 AA182626 AA182603
111829 46636 1 AF074991 R36070
104668 82752 1 AW964385 AA007312 AI081711 AA318253 AW891655 T99192
127553 202308 2 AA505046 AW969109 AA505047
120379 34624.3 AL042725 BE063316 AW975610 AA457591 BE062092 AI655202 AA714296 A1267264 A1075321 AA223286 AA071122 AA227849
AA216700 AI696002 AA101867 AA099426 AA135997 AL041698 T02815 T51824 AA207189 T59230 T51868 AA663341 BE165757
AW818104 AW392886 AA584918 AA099408 AW856396 AW861859 AA053045
127701 405284 1 AA679064 AA935466
128410 288073 1 AA424107 AA452788
114625 111686 1 AA081507 AA070071 AA070840 AA084362
109026 150431 1 AA157811 AA836869
108409 113869 1 AA075631 AA075578
100687 tιgr_HT3291 L18862
109326 genbank_AA210719 AA210719
123762 genbank_AA610013 AA610013
116548 genbank D20433 D20433
125145 entrez W38001 W38001
125153 entrez_W38294 W38294
116995 genbank_H83928 H83928
102649 genbank_U68133 U68133
118456 genbank_N66580 N66580
102860 entrez_X00368 X00368
120715 genbaπk_AA292700 AA292700
120749 genbank_AA303235 AA303235
113663 genbank_T95909 T95909
113889 genbank_W72720 W72720
108258 genbank AA063269 AA063269
101046 entrez_K01160 K01160
129990 genbank_N30316 N30316
122746 genbaπk_AA458791 AA458791
124046 genbank_F10243 F10243
108436 genbank_AA078801 AA078801
124197 genbank_H52921 H52921
101447 entrez_M21305 M21305
108852 genbank_AA133131 AA133131
101697 entrez_M64358 M64358
108931 geπbaπk_AA147186 AA147186
101909 entrez_S69265 S69265
117816 genbank_N48872 N48872
119154 genbaπk_R61293 R61293
119241 genbank_T12559 T12559
119310 genbank_T40427 T40427
119347 genbank_T64349 T64349
119529 entrez_W38053 W38053
112467 genbank_R65706 R65706
112533 genbank_R69886 R69886
112588 genbank_R77302 R77302
121082 genbank_AA398722 AA398722
123305 geπbank.AA496133 AA496133
123328 genbank_AA496968 AA496968
100547 tιgr_HT2219 M57417
123490 genbaπk_AA599723 AA599723
TABLE 45A 90 GENES DOWN-REGULATED IN RHEUMATOID ARTHRITIS COMPARED TO NORMAL BODY
Table 45A lists about 90 geneε down regulated in rheumatoid arthntis These were selected from 35403 probesets on the Aflymetnx/Eos Hu01 GeneChip
Pkey Unique Eos probeset identifier number ExAccn Exemplar Accesεion number, Genbank acceεsion number
UnigenelD Unigene number Unigene Title Unigene gene title Pkey ExAccn UnigenelD Unigene Title
100137 D13627 Hs 15071 chaperonin containing TCP1 , subunit 8 (t
100240 D31767 Hs 75416 DAZ assxiated protein 2
100289 D45248 Hs 179774 proteasome (prosome, macropain) activato
100658 HG2855 HT2995 Hs 75452 heat shxk 70kD protein 2
100763 HG3597-HT3800 gb Human major histxompatibility comple
100779 HG3731-HT4001 Hs 302063 immunoglobulin heavy constant mu
101091 L06132 Hs 149155 voltage dependent anion channel 1
101155 L13972 Hs 301698 sialyltransferase 4A (beta-galactosidaεe
102223 U24685 gb Homo εapiens immunoglobulin heavy cha
102282 U31383 Hs 79126 guanine nucleotide binding protein 10
102378 U40369 Hs 28491 spermidme/εpermine NI-xetyltransferase
102386 U40998 Hs 81728 uπc119 (C elegans) homolog
102389 U41371 Hs 75916 splicing fxtor 3b, subunit 2, 145kD
102480 U50327 Hs 1432 protein kinase C substrate 80K-H
102566 U59752 Hs 303091 plxkstπn homology, Sx7 and coiled/coi
102605 U64444 Hs 181369 ubiquitin fusion degradation 1-lιke
102693 U73824 Hs 183684 eukaryotic translation initiation factor
102710 U77827 Hs 113207 G protein-coupled receptor 30
102920 X12451 Hs 78056 cathepsin L
102929 X13238 Hs 74649 cytochrome c oxidase subunit Vic
103166 X67951 Hs 180909 peroxiredoxin 1
103283 X80199 Hs 83422 MLN51 protein
103463 Y00281 Hs 2280 nbophoππ I
103835 AA172215 Hs 93748 Homo sapiens cDNA FLJ 14676 fis, clone NT
104796 AA029368 Hs 33026 hypothetical protein PP2447
105714 AA291429 Hs 12211 GDP-fucose tranεporter 1
105927 AA402968 Hs 332040 hypothetical protein MGC13010
105945 AA404512 Hs 14453 interferon conεensus sequence binding pr
106001 AA410986 Hs 8963 Homo sapiens mRNA full length insert cDN
106027 AA412119 Hs 234799 breakpoint cluster region
106227 AA429262 Hs 19613 ESTs
106295 AA435664 Hs 8583 similar to APOBEC1
106417 AA448008 Hs 261828 G protein-coupled rxeptor kinase 7
107391 W02877 Hs 284294 Breakpoint cluster region protein, uteπ
109107 AA169180 Hs 269280 ESTs
109685 F09325 Hs 28102 ESTs
110021 H11252 Hs 31037 ESTs
110738 H99370 Hs 139648 kinesm family member 1C
112746 R93237 Hs 74170 metallothionein 1E (functional)
113059 T26925 Hs 172684 vesicle assxiated membrane protein 8 (e
113822 W47350 Hs 17466 retinoic xid rxeptor responder (tazaro
113859 W67225 Hs 13273 KIAA0592 protein
113909 W78127 Hs 9956 hypothetical protein FLJ20259
114693 AA122158 Hs 300683 Homo sapiens cDNA FLJ12825 fis, clone NT
115399 AA283182 Hs 92023 ∞re histone macroH2A22
116606 D80217 Hs 259842 protein kinase, AMP-activated, gamma 2 n
116633 F02702 Hs 268726 ESTs, Highly similar to ZN91.HUMAN ZINC
119254 T15837 Hs 279009 matnx Gla protein
119493 W35384 Hs 50477 RAB27A, member RAS oncogene family
120108 W95696 Hs 16803 LUC7 (S cereviεiae) like
120886 AA365566 Hs 301342 hypothetical protein MGC4342
120953 AA397911 Hs 97499 ESTs, Weakly similarto unknown [H sapie
121303 AA402441 Hs 303197 B-cell CLL/lymphoma 7C
121547 AA412448 Hs 104777 ESTs
123495 AA599850 Hs 106747 seπne carboxypeptidase 1 precursor prot
123608 AA609144 Hs 112651 ESTs
123749 AA609949 Hs 112790 EST
124763 R39610 Hs 76288 calpam 2, (m/ll) large subunit
125366 H60192 Hs 76853 Homo εapienε mRNA, cDNA DKFZp434N1728 (f
125657 AA481719 Hs 150540 Homo εapienε, clone IMAGE 3954961, mRNA,
125670 AI432621 Hs 82685 CD47 antigen (Rh related antigen, integr
125882 H45538 Hs 101448 metastasiε aεεxiated 1
126541 AA204913 Hs 7854 zinc/iron regulated transporter-tike
126715 R70160 Hε 241552 KIAA0268 protein
126817 AA478642 Hε 291623 ESTs, Weakly similar to unnamed protein
127112 A1143906 Hs 125103 ESTs
127273 AA335263 Hs 144950 ESTs
127615 AA718919 gb zv88a04 s1 Soares_NhHMPu S1 Homo sapi
127635 AA766903 Hs 116346 ESTs, Highly similar to A46297 beta-1 ,6-
128528 R39234 Hs 251699 ESTε, Weakly εimilar to IDN4-GGTR14 [H s
129398 AA437374 Hs 234573 Homo sapiens mRNA for TL132
129621 AA489459 Hs 301005 purine πch element binding protein B
131037 AA256171 Hs 22391 chromosome 20open reading frame 3
131328 V01512 Hs 25647 v-fos FBJ munne osteosarcoma viral onco
131631 AA486868 Hs 29802 slit (Drosophila) homolog 2
132079 H67964 Hs 38694 ESTs
132455 T15774 Hs 4892 Homo sapieπε clone 24841 mRNA εequence
132582 AA318547 Hε 278712 eukaryotic translation initiation factor
132610 AA443114 Hs 5326 ammo acid syεtem N tranεporter 2, porcu
132755 AA609201 Hs 182635 ESTε
133192 AA393804 Hs 67052 vacuolar protein sorting 26 (yeast homol 133437 R57419 Hs 7370 phosphotidy nositol transfer protein, b
133449 AA094989 Hs 7381 voltage dependent anion channel 3
133649 AA479139 Hs 75393 acid phosphatase 1, soluble
133814 M33882 Hs 76391 myxovirus (influenza) resistance 1 , homo
134378 AF006088 Hs 82425 xtin related protein 2/3 complex, subun
134419 L08044 Hs 82961 trefoil factor 3 (intestinal)
134548 U41515 Hs 333495 Deleted in split hand/split-foot 1 regio
134776 J05582 Hs 89603 mucin 1, transmembrane
135032 AA243497 Hs 173685 hypothetical protein FLJ12619
TABLE 45B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accesεion numbers
Pkey CAT number Accessions
127615 380951.1 AA626215AA718919 100763 tιgr_HT3800 X12432Y08693 102223 221.265 AF013616AA300945 X65907AF062264AF062250Z47228 Z75389Z75374AF062152AF062146 Z75398 X64153AF062101 AF062218 S59161 Z75392AF062196 AF062192X65904U24685 AF062181 Z47241 Z75376AF062217Z47234X64152AF062187AF062173AF062158Z47229 M74018 M74021 X54441 M84512 L29115 M84508Z75384AJ244983AJ245240AJ245030AJ245042 M26998 L03635 S64473AJ244997AJ245013 AJ279535 U89766 AF174049 AF174085 AF174086 U97246AJ245011 AJ245017AJ245028AJ245041 AJ245051 AJ245065 AJ245236 U22391 Z49143Z74665AF087428 S66098Z70650AJ244929AF006528AF022004AF021983 U00556AJ245035Z70617 Z70605AJ245052AJ245046 AF087424AF174054S67110 U21257 U21267 U21268Z35492U71103AF021991 L23518Z70644AJ245036 Z49141 AF089001 Z74695Z46304 AF021957AF021990AF022005AF052527AF021947Z70604Z70610AF062104Z49135 X64235Z46341 Z46305Z46307Z49136AJ244996 Z46342AJ244931 AJ244935AJ244937AJ244938 L12192AJ244939 AJ244940AJ244941 Z46308AJ244962AF062234AJ244973AJ244984 AJ244985AF174088 AJ279519 AJ279521 AJ279526AJ245009AJ279531 AJ245008AJ244994AJ244991 AJ244990AJ244988AJ244987 X87440 AJ245238 Z70625 Z70626Z70641 Z70640 Z70643AJ244975Z70616 Z70637AJ244982AJ244967 AJ239377AJ245057AF021948AF107239 AJ245040 L34163 AF062231 Z70627AF062113AF006527 AF174041 AJ279537Z70642 U00497Z70639AJ245054AJ244960AJ279524AJ244943 AJ249631 AF035041 AJ245039AJ245050AF107233AJ239362AJ244969Z46278Z46290Z46274Z46281 AJ239351 L25293AJ244944AJ244951 Z46280Z46270AJ245043Z46276AF107241 Z46271 Z46277AJ245034Z46273AJ244992Z46282 Z70638Z46275AJ244972 Z46272Z46279 Z46269 AF087422 M74469 X64159AF103243 X64156AJ244942Z46316 AJ222547 Z46322Z46324Z46326Z46327AJ222556Z46329 Z46330 Z46302AJ222561 AJ222549AJ222568AJ222570AJ222571 Z49139AJ222578AJ222562AJ222577Z46323AJ222576AJ222566Z46315 AJ222557 AJ222564AJ222559AJ222573AJ222575 Z46318AJ222548 Z46319AJ222552AJ222550AJ222567AJ222558AJ222563Z46317 X87438AJ222555AJ240581 AF103161 AJ240580AJ240594Y17929AJ240553AJ240573AJ240558AJ240555Y17927Y17949AJ240561 Y17948 Y17933Y17947Y17944Y17928Y17931 Y17934AJ240595Y17943Y17932Y17930AJ240590AJ240560Y17945AJ240556 S79918AF103278 AW364256AF103299AF103122X75022AF004937 Z30557Z30677Z30573Z30576Z30561 Z30674Z30562Z30675AW403129AI203192 AW404253AW237246AI654630 H61354
Table 46A lists about 714 genes upregulated in esophageal cancer relative to normal body tissues These geneε were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genechip array Gene expression data for exh probeset obtained from this analysis was expresεed aε average intensity (Al), a normalized value reflxting the relative level of mRNA expresεion
Table 47A lists about 113 genes upregulated in esophageal tumors relative to normal esophaguε These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genechip array Gene expresεion data for exh probeεet obtained from thiε analysis was expresεed aε average intensity (Al), a normalized value reflxting the relative level of mRNA expression
Table 48A lists about 162 genes downregulated in esophageal tumors relative to normal esophagus These genes were selxted from 59680 probesets on the Eoε/Affymetπx Hu03 Genxhip array Gene expreεεion data for exh probeεet obtained from this analysis was expreεεed as average intensity (Al), a normalized value reflxting the relative level of mRNA expression
TABLE 46A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcesεion number UnigenelD Unigene number Unigene Title Unigene gene title
R1 90th percentile of esophageal tumor Als divided by the 70th percentile of normal tissue Als, where the 15th percentite of the nomial tisεue Als was subtrxted from both the numerator and denominator
Pkey ExAccn UnigenelD Unigene Title R1
413808 J00287 Homo sapiens mRNA for caldesmoπ, 3' UTR 31 57
411243 AB039886 Hs 69319 CA11 2606
422168 AA586894 Hs 112408 S100 calcium-binding protein A7 (psonas 2565
401781 Target Exon 2323
424098 AF077374 Hs 139322 εmall proline-πch protein 3 21 35
425211 M18667 Hs 1867 progastncsin (peps ogen C) 2037
417366 BE185289 Hs 1076 εmall proliπe-πch protein 1B (comifin) 2033
401780 NM.005557* Homo εapiens keratin 16 (fxa 1894
421948 L42583 Hs 334309 keratin 6A 18 13
400289 X07820 Hs 2258 matnx metalloprotemase 10 (stromelysin 1801
429538 BE182592 Hs 11261 small proline rich protein 2A 17 31
400666 NM.002425 Homo sapiens matrix metallopro 17 28
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial 1696 430520 NM.016190 Hs 242057 chromosome 1 open reading frame 10 1635
408522 AI541214 Hs 46320 Small proline rich protein SPRK [human, 16 22
413278 BE563085 Hε 833 interferon-stimulated protein, 15 kDa 1564
421582 AI910275 trefoil factor 1 (breaεt cancer, estroge 1486
425679 X05997 Hε 159177 lipase, gastric 1453
421773 W69233 Hs 112457 ESTs 14 26
433091 Y12642 Hs 3185 lymphocyte antigen 6 complex, Ixus D 1426
422158 L10343 Hs 112341 protease inhibitor 3, skm-deπved (SKAL 1393
444325 AW152618 Hs 16757 ESTs 13 24
431723 AW058350 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 13 19
420783 AI659838 Hs 99923 Ixtin, gaiactoside-binding soluble, 7 11 98
423673 BE003054 Hs 1695 matrix metalloproteinase 12 (macrophage 10 99
426350 NM.003245 Hs 2022 transglutaminase 3 (E polypeptide, prote 1077
432239 X81334 Hs 2936 matnx metalloprotemase 13 (collagenase 1031
446292 AF081497 Hs 279682 Rh type C glycoprotein 969
421978 AJ243662 Hs 110196 NICE-1 protein 9 68
448811 AI590371 Hs 199460 ESTs 938
453331 AI240665 ESTs 937
423634 AW959908 Hs 1690 hepaπn binding growth fxtor binding pr 9 28
413719 BE439580 Hs 75498 small inducible cytokine εubfamily A (Cy 918
406687 M31126 matnx metalloprotemase 11 (stromelysin 9 13
454034 NM 000691 Hs 575 aldehyde dehydrogenase 3 family, member 9 04
450701 H39960 Hs 288467 hypothetical protein XP.098151 877
418686 Z36830 Hs 87268 annexm A8 876
421110 AJ250717 Hs 1355 cathepsin E 842
407788 BE514982 Hs 38991 S100 calcium binding protein A2 842
424012 AW368377 Hs 137569 tumor protein 63 kDa with εtrong homolog 838
423217 NM 000094 Hs 1640 collagen, type VII, alpha 1 (epidermolyε 8 18
427666 AI791495 Hs 180142 calmodulin like skin protein (CLSP) 8 11
450375 AA009647 a disintegnn and metalloprotemase doma 803
401785 NM.002275* Homo sapienε keratin 15 (KRT1 797
445891 AW391342 Hs 199460 DPCR1 protein 795
437053 AU077018 Hs 3235 keratin 4 793
423271 W47225 Hs 126256 interieukin 1, beta 780
409757 NM 001898 Hs 123114 cystat SN 774
444342 NM_014398 Hs 10887 similar to lysosome-asεxiated membrane 764
452838 U65011 Hs 30743 preferentially expressed antigen in mela 758
429211 AF052693 Hs 198249 gap junction protein, beta 5 (connexm 3 7 55
428330 L22524 Hs 2256 matnx metalloprote ase 7 (matπlysm, 726
448045 AJ297436 Hs 20166 prostate stem cell antigen 7 14
408243 Y00787 Hs 624 interleukin 8 7 13
429359 W00482 Hs 2399 matnx metalloproteinaεe 14 (membrane in 708
437191 NM 006846 Hs 331555 εeπne protease inhibitor, Kazal type, 5 7 04
407366 AF026942 Hs 17518 gb Homo sapiens cιg33 mRNA, partial sequ 704
424687 J05070 Hs 151738 matnx metalloprotemase 9 (gelatinase B 6 98
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 689
414774 X02419 Hs 77274 plasminogen xtivator, urokmase 685
439926 AW014875 Hs 137007 ESTs 684
446921 AB012113 Hs 16530 small inducible cytokine subfamily A (Cy 682
429259 AA420450 Hs 292911 Plakophilin 677
419741 NM 007019 Hs 93002 ubiquitin earner protein E2-C 671
424834 AK001432 . Hs 153408 Homo εapiens cDNA FLJ10570 fiε, clone NT 667
429228 AI553633 Hs 326447 ESTε 661
426312 AF026939 Hs 181874 interferon-mduced protein with tetratπ 660
431211 M86849 Hs 323733 gap junction protein, beta 2, 26kD (conn 6 58
441362 BE614410 Hs 23044 RAD51 (S cerevisiae) homolog (E coli Re 655
414987 AA524394 Hs 294022 hypothetical protein FLJ14950 654
446989 AK001898 Hs 16740 hypothetical protein FLJ11036 653
409632 W74001 Hs 55279 seπne (or cysteine) proteinase inhibito 651
422166 W72424 Hs 112405 S100 calcium-binding protein A9 (calgran 649
417515 L24203 Hs 82237 ataxia-telangixtaεia group D-ass∞iated 648
428471 X57348 Hs 184510 stratitin 646
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 645
444381 BE387335 Hs 283713 ESTs, Weakly similarto S64054 hypotheti 644
401747 Homo sapienε keratin 17 (KRT17) 642
421508 NM.004833 Hs 105115 abεent in melanoma 2 642
416768 AA363733 Hs 1032 regenerating lεlet-deπved 1 alpha (pane 642
417079 U65590 Hs 81134 interleukin 1 rxeptor antagonist 641
432374 W68815 Hs 301885 Homo εapienε cDNA FLJ 11346 fiε, clone PL 638
422596 AF063611 Hs 118633 2'-5'-olιgoadenylate εynthetase-lιke 638
409601 AF237621 Hs 80828 keratin 1 (epidermolytic hyperkeratosiε) 636
444781 NM 014400 Hs 11950 GPI-anchored metastasis assxiated prote 635
407811 AW190902 Hs 40098 cysteine knot superfamily 1, BMP antagon 6 33
425415 M13903 Hs 157091 mvolucπn 632
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheππ (plxenta 6 30
415989 AI267700 ESTs 623
406673 M34996 Hs 198253 major histxompatibility complex, class 6 21
449228 AJ403107 Hs 148590 protein related with psoriasis 621
436749 AA584890 Hs 5302 lectin, gaiactoside-binding, soluble, 4 6 18
444527 NM 005408 : Hs 11383 small inducible cytokine subfamily A (Cy 606
418663 AK001100 Hs 41690 desmocollm 3 604
428368 BE440042 Hs 83326 matnx metalloprotemase 3 (stromelysin 598
414915 NM 002462 ! Hs 76391 myxovirus (influenza) resistance 1, homo 5 96 452401 NM 007115 Hs.29352 tumor necroεis factor, alpha-induced pro 5.93
452304 AA025386 Hs.61311 ESTs, Weakly similar to S10590 cysteine 5.92
418004 U37519 Hε.87539 aldehyde dehydrogenase 3 family, member 5.92
424620 AA101043 Hs.151254 kallikrein 7 (chymotryptic, εtratum com 5.84
425650 NM.001944 Hs.1925 desmoglein 3 (pemphigus vulgaris antigen 5.76
400665 NM_002425:Homo sapienε matrix metallopro 5.75
427747 AW411425 Hs.180655 εerine/threonine kinase 12 5.72
425247 NM 005940 Hε.155324 matrix metalloproteinase 11 (stromelyεin 5.72
414004 AA737033 Hε.7155 ESTε, Moderately similar to 2115357 A TYK 5.71
422765 AW409701 Hs.1578 baculoviral IAP repeat-containing 5 (εur 5.70
439606 W79123 Hs.58561 G protein-coupled receptor 87 5.70
445417 AK001058 Hs.12680 Homo sapienε cDNA FLJ10196 fiε, clone HE 5.68
433447 U29195 Hs.3281 neuronal pentraxin II 5.67
428227 AA321649 Hs.2248 εmall inducible cytokine εubfamiiy B (Cy 5.64
408000 L11690 Hs.198689 bullous pemphigoid antigen 1 (230/240kD) 5.62
413219 AA878200 Hs.118727 Homo sapiens cDNA FLJ13692 fis, clone PL 5.60
428450 NM 014791 Hs.184339 KIAA0175 gene product 5.53
424408 AI754813 Hs.146428 collagen, type V, alpha 1 5.50
416250 AA581386 Hs.73452 hypothetical protein MGC10791 5.48
447164 AF026941 Hs.17518 Homo sapiens cig5 mRNA, partial sequence 5.47
412326 R07566 Hs.73817 small inducible cytokine A3 (homologous 5.44
439223 AW238299 Hs.250618 UL16 binding protein 2 5.44
431629 AU077025 Hs.265827 interferon, alpha-inducible protein (clo 5.42
402994 NM_002463*:Homo sapiens myxovirus (influ 5.40
447333 BE090580 Hs.70704 hypothetical protein dJ616B8.3 5.40
426991 AK001536 Homo εapienε cDNA FLJ10674 fiε, clone NT 5.36
454241 BE144666 gb:CM2-HT0176-041099-017-c02 HT0176 Homo 5.33
408716 AI567839 Hs.151714 Homo sapiens mRNA for Kl AA1769 protein, 5.32
449722 BE280074 Hs.23960 cyclin B1 5.31
428434 AW363590 Hs.65551 Homo sapieπε, Similar to DNA segment, Ch 5.30
426283 NM 003937 Hs.169139 kynureninase (L-kynurenine hydrolase) 5.29
418941 AA452970 Hs.239527 E1B-55kDa-associated protein 5 5.29
417720 AA205625 Hs.208067 ESTs 5.29
424008 R02740 Hs.137555 putative chemokine rxeptor; GTP-binding 5.28
419216 AU076718 Hs.164021 εmall inducible cytokine εubfamily B (Cy 5.27
431620 AA126109 Hs.264981 2'-5'-oligoadeπylate εynthetase 2 (69-71 5.26
430280 AA361258 Hε.237868 interleukin 7 rxeptor 5.25
422627 BE336857 Hs.118787 transforming growth fxtor, beta-induced 5.24
402075 ENSP00000251056*:Plaεma membrane calcium 5.24
413753 U17760 Hs.75517 laminin, beta 3 (nicein (125kD), kaliniπ 5.24
445537 AJ245671 Hs.12844 EGF-like-domain, multiple 6 5.22
446619 AU076643 Hs.313 εxreted phosphoprotein 1 (osteopontiπ, 5.22
418558 AW082266 Hs.86131 Faε (TNFRSF6)-assxiated via death dόmai 5.21
422440 NM 004812 Hs.116724 aido-keto reductaεe family 1, member B10 5.20
428188 M98447 Hs.22 tranεglutaminase 1 (K polypeptide epider 5.20
406663 U24683 Hs.293441 immunoglobulin heavy constant mu 5.19
409178 BE393948 Hs.50915 kallikrein 5 5.15
443426 AF098158 Hε.9329 chromosome 20 open reading frame 1 5.14
410700 AA352335 Hs.65641 hypothetical protein FLJ20073 5.10
418054 NM 002318 Hs.83354 lysyl oxidase-like 2 5.09
452281 T93500 Hs.28792 Homo sapiens cDNA FLJ11041 fis, clone PL 5.09
412471 M63193 Hs.73946 endothelial cell growth fxtor 1 (platel 5.08
411274 NM 002776 Hs.69423 kallikrein 10 5.07
407756 AA116021 Hs.38260 ubiquitin spxific protease 18 5.03
409893 AW247090 Hs.57101 minichromosome maintenance deficient (S. 5.03
433800 AI034361 Hs.135150 lung type-l cell membrane-asεxiated gly 5.02
412755 BE144306 Hs.179891 ESTε, Weakly εimilar to P4HA_HUMAN PROLY 5.02
416530 U62801 Hε.79361 kallikrein 6 (neurosin, zyme) 5.02
429058 AF138863 Hs.35254 hypothetical protein FLB6421 5.00
442117 AW664964 Hs.128899 ESTε; hypothetical protein for IMAGE:447 5.00
426711 AA383471 Hs.343800 conεerved gene amplified in oεteoεarcoma 4.97
405770 NM_002362:Homo εapienε melanoma antigen, 4.96
444783 AK001468 Hε.62180 anillin (Droεophila Scrapε homolog), xt 4.94
420859 AW468397 Hε.100000 S100 calcium-binding protein A8 (calgran 4.94
426866 U02330 Hε.172816 neuregulin 1 4.93
423017 AW178761 Hε.227948 εerine (or cyεteine) proteinase inhibito 4.92
455601 AI368680 Hs.816 SRY (sex determining region Y)-box 2 4.91
409956 AW103364 Hε.727 inhibin, beta A (xtivin A, activin AB a 4.90
427786 BE407863 Hs.256871 ' ESTs 4.87
409420 Z15008 Hε.54451 laminin, gamma 2 (nicein (100kD), kalini 4.86
444371 BE540274 Hε.239 forkhead box M1 4.86
431009 BE149762 Hε.48956 gap junction protein, beta 6 (connexin 3 4.85
434826 AF155661 Hε.22265 pyruvate dehydrogenase phosphatase 4.84
406690 M29540 Hε.220529 carcmoembryonie antigen-related cell ad 4.83
409402 AF208234 Hs.695 cystatin B (stefin B) 4.81
408202 AA227710 Hs.43658 DKFZP586L151 protein 4.79
401994 Target Exon 4.77
425292 NM.005824 Hs.155545 37 kDa leucine-rich repeat (LRR) protein 4.74
421574 AJ000152 Hs.105924 defeπsin, beta 2 4.69
429299 AI620463 Hs.347408 hypothetical protein MGC13102 4.69
422109 S73265 Hε.1473 gaεtrin-releasing peptide 4.68
439453 BE264974 Hε.6566 thyroid hormone rxeptor interactor 13 4.68
407944 R34008 Hε.239727 desmocollin 2 4.67 411296 BE207307 Hs 10114 growth suppresεor 1 465
433364 AI075407 Hs 296083 ESTε, Moderately similar to 154374 gene 465
425234 AW152225 Hs 165909 ESTs Weakly similar to 138022 hypotheti 461
421335 X99977 Hε 103505 ARS component B 460
422515 AW500470 Hs 117950 multifunctional polypeptide similar to S 459
453779 N35187 Hs 43388 28kD interferon responsive protein 459
423575 C18863 Hs 163443 penostin (OSF-2os) 459
417308 H60720 Hs 81892 KIAA0101 gene product 458
428651 AF196478 Hε 188401 annexm A10 458
424354 NM.014314 Hs 145612 RNA helicase 458
404996 Target Exon 456
404240 NM.018950 Homo sapiens major histxompat 456
453095 AW295660 Hs 252756 ESTs 455
410407 X66839 Hs 63287 carbonic anhydrase IX 455
418678 NM 001327 Hs 87225 caπcer/testis antigen (NY-ESO-1) 455
450685 L15533 Hs 423 pancreatitis-associated protein 454
425483 AF231022 Hs 158159 FAT tumor suppreεsor (Drosophila) homolo 453
425397 J04088 Hs 156346 topoisomerase (DNA) II alpha (170kD) 452
408380 AF123050 Hs 44532 diubiquitm 447
443859 NM 013409 Hs 9914 follistatin 446
411773 NM 006799 Hs 72026 protease, senne, 21 (testism) 444
412140 AA219691 Hs 73625 RAB6 interacting, kinesm like (rabkines 444
421777 BE562088 Hs 108196 HSPC037 protein 444
408908 BE296227 Hs 250822 seππe/threonine kmase 15 443
408122 AI432652 Hs 42824 hypothetical protein FLJ10718 442
422487 AJ010901 Hs 198267 mucin 4, tracheobronchial 442
400419 AF084545 Target 442
452571 W31518 Hs 34665 ESTs 441
430044 AA464510 Hs 152812 ESTs 441
414732 AW410976 Hs 77152 minichromosome maintenance deficient (S 439
448111 AA053486 Hs 20315 interferon-induced protein with tetratn 439
443347 AI052543 Hs 133244 melanoma derived leucine zipper, extra n 439
453884 AA355925 Hs 36232 KIAA0186 gene product 438
436481 AA379597 Hs 5199 HSPC150 protein similar to ubiquitin-con 437
417900 BE250127 Hs 82906 CDC20 (cell division cycle 20, S cerevi 437
424046 AF027866 Hs 138202 senne (or cysteine) proteinase inhibito 437
427983 M17706 Hs 2233 colony stimulating fxtor 3 (granulxyte 436
448357 N20169 Hs 108923 RAB38, member RAS oncogene family 436
409041 AB033025 Hs 50081 Hypothetical protein, XP.051860 (KIAA119 434
439999 AA115811 Hs 6838 ras homolog gene family, member E 434
410361 BE391804 Hs 62661 guanylate binding protein 1, interferon- 434
409703 NM_006187 Hs 56009 2'-5'-olιgoadeπylate synthetase 3 (100 k 432
402447 C1000201 gι|204416|gb|AAA02627 1| (L0519 431
426514 BE616633 Hs 170195 bone morphogenetic protein 7 (osteogenic 428
432731 R31178 Hs 287820 fibronxtin 1 427
422397 AJ223366 Hs 116051 Homo sapiens cDNA FLJ22495 fis, clone H 427
413670 AB000115 Hs 75470 hypothetical protein, expressed in ostx 425
425580 L11144 Hs 1907 galanm 425
421506 BE302796 Hs 105097 thymidine kinase 1, soluble 423
409433 AA074382 Hs 135255 ESTs 423
430630 AW269920 Hs 2621 cystatm A (stefin A) 422
447343 AA256641 Hε 236894 ESTs, Highly similar to S02392 alpha-2-m 421
407047 X65965 gb H sapiens SOD-2 gene for manganese su 420
432375 BE536069 Hs 2962 S100 calcium binding protein P 420
434449 AW953484 Hs 3849 hypothetical protein FLJ22041 similarto 419
417866 AW067903 Hs 82772 collagen, type XI, alpha 1 4 19
436291 BE568452 Hs 344037 protein regulator of cytokinesis 1 418
418140 BE613836 Hs 83551 microfibπllar-asεxiated protein 2 417
410286 AI739159 Hs 61898 " DKFZP586N2124 protein 416
448844 AI581519 Hs 177164 ESTs 416
432680 T47364 Hs 278613 interferon, alpha-inducible protein 27 416
417599 AA204688 Hs 62954 ESTs 416
402992 Target Exon 4 15
429500 X78565 Hs 289114 hexabrxhion (tenascm C, cytotxtin) 414
422100 AI096988 Hs 111554 ADP-πbosylation factor-like 7 413
409512 AW979187 Hs 293591 melanoma differentiation associated prot 412
446985 AL038704 Hs 156827 ESTε, Weakly similar to ALU1.HUMAN ALU S 411
407137 T97307 gb ye53h05 s1 Soares fetal liver spleen 410
411263 BE297802 Hs 69360 kinesm-like 6 (mitotic centromere-assx 4 10
439979 AW600291 Hs 6823 hypothetical protein FLJ10430 410
423905 AW579960 Hs 135150 lung type-l cell membrane-assxiated gly 409
427337 Z46223 Hs 176663 Fc fragment of IgG, low affinity lllb, r 408
417933 X02308 Hs 82962 thymidylate synthetase 408
418689 AI360883 Hs 274448 hypothetical protein FLJ 11029 406
417678 X06560 Hs 82396 2',5'-olιgoadeπylate synthetase 1 (40-46 406
451541 BE279383 Hs 26557 plakophilin 3 406
433848 AF095719 Hs 93764 carboxypeptidase A4 406
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 404
429599 AA806106 Hs 123664 ESTs 403
450823 T81223 Hs 22011 complement-c1q tumor nxrosis factor-rel 402
423787 AJ295745 Hs 236204 nuclear pore complex protein 400
431250 BE264649 Hs 251377 taxol resiεtance associated gene 3 400
416091 AF295370 Hs 283082 '. defensm, beta 3 387 427557 NM.002659 Hs 179657 plasminogen activator, urokmase recepto 397
427099 AB032953 Hε 173560 odd Oz/ten homolog 2 (Drosophila, mous 397
402408 NM.030920* Homo sapiens hypothetical pro 397
424927 AW973666 Hs 153850 hypothetical protein C321D24 395
414907 X90725 Hs 77597 polo (Drosophia) like kinase 395
452888 AW955454 Hs 30942 ephnn B2 395
456525 AW468397 Hs 100000 S100 calcium binding protein A8 (calgraπ 395
450983 AA305384 Hs 25740 ER01 (S cerevisiae) like 394
419693 AA133749 Hs 301350 FXYD domain containing ion transport reg 394
420596 NM.002692 Hs 99185 polymerase (DNA directed), epsilon 2 394
422094 AF129535 Hs 272027 F-box only protein 5 394
414945 BE076358 Hs 77667 lymphxyte antigen 6 complex, Ixus E 393
404286 C6001909 gι|704441|dbj|BAA18909 1| (D298 393
423961 D13666 Hs 136348 penostin (OSF-2os) 392
426075 AW513691 Hs 270149 ESTε, Weakly similar to 2109260A B cell 391
447377 X77343 Hs 334334 transcription factor AP-2 alpha 391
435066 BE261750 Hs 4747 dyskeratosiε congemta 1, dyεkeπn 391
446998 N99013 Hs 16762 Homo εapiens mRNA, cDNA DKFZp564B2062 (f 391
421904 BE143533 Hs 109309 hypothetical protein FLJ20035 390
441553 AA281219 Hs 121296 ESTs 390
428093 AW594506 Hs 104830 ESTs 390
441020 W79283 Hs 35962 ESTs 389
447078 AW885727 Hs 9914 ESTs 389
437044 AL035864 Hs 69517 differentially expressed in Faπconi's an 389
417621 AV654694 Hs 82316 interferon induced, hepatitis C-associat 387
424905 NM 002497 Hε 153704 NIMA (never in mitoεiε gene a) related k 387
426059 BE292842 Hε 166120 interferon regulatory fxtor 7 3 86
419833 AA251131 Hs 220697 ESTε 385
451807 W52854 Hs 27099 hypothetical protein FLJ23293 similar to 385
422530 AW972300 Hs 118110 bone marrow stromal cell antigen 2 383
452203 X57522 transporter 1 , ATP-binding cassette, sub 383
414020 NM 002984 Hs 75703 small inducible cytokine A4 (homologous 383
414809 AI434699 Hs 77356 tranεfemn rxeptor (p90, CD71) 383
442599 AF078037 Hs 324051 ReiA assxiated inhibitor 382
405387 NM_022170* Homo sapiens Williams-Beuren 382
449539 W80363 Hs 58446 ESTs 382
419079 AW014836 Hs 18844 ESTs 381
410434 AF051152 Hs 63668 toll like receptor 2 381
408660 AA525775 ESTs, Moderately similar to PC4259 fem 380
409142 AL136877 Hs 50758 SMC4 (structural maintenance of chromoso 380
435099 AC004770 Hs 4756 flap structure-spxific endonuclease 1 380
444006 BE395085 Hs 10086 type I transmembrane protein Fn14 379
426761 AI015709 Hs 172089 Homo sapienε mRNA, cDNA DKFZp586l2022 (f 379
444665 BE613126 Hs 47783 B aggressive lymphoma gene 378
427528 AU077143 Hs 179565 minichromosome maintenance deficient (S 378
414561 AI064813 Hs 195155 Homo sapiens amino xid transport syεtem 378
411789 AF245505 Hs 72157 Adlican 377
428311 NM 005651 Hs 183671 tryptophan 2,3-dιoxygenaεe 377
449378 AW664026 Hs 59892 ESTε 376
449961 AW265634 Hs 133100 ESTε 376
443378 AW392550 Hs 9280 proteasome (prosome, mxropain) subunit, 375
407242 M18728 gb Human nonspxific crossrexting antig 375
414416 AW409985 Hs 76084 hypothetical protein MGC2721 375
422283 AW411307 Hs 114311 CDC45 (cell division cycle 45, S cerevis 375
422675 BE018517 Hε 119140 eukaryotic translation initiation fxtor 374
422699 BE410590 Hε 119257 emsl sequence (mammary tumor and squamou 374
441954 AI744935 Hs 8047 Fanconi anemia, complementation group G 374
410290 AA402307 Hs 322844 hypothetical protein DKFZp564A176 373
422648 D86983 Hs 118893 Melanoma asεxiated gene 372
428953 AA306610 Hs 348183 tumor necrosis fxtor receptor superfami 371
443883 AA114212 Hs 9930 senne (or cyεteine) proteinase inhibito 371
428728 NM.016625 Hε 191381 hypothetical protein 371
400245 Eos Control 371
442432 BE093589 Hε 38178 hypothetical protein FLJ23468 370
428484 AF104032 Hs 184601 solute camerfamily 7 (cationic ammo 370
424840 D79987 Hs 153479 extra spindle poles, S cerevisiae, homo 370
440659 AF134160 Hs7327 claudin 1 369
414821 M63835 Hs 77424 Fc fragment of IgG, high affinity la, re 367
413063 AL035737 Hs 75184 chitmase 3 like 1 (cartilage glycoprote 367
425081 X74794 Hs 154443 mimchromoεome maintenance deficient (S 366
409432 D49372 Hε 54460 εmall inducible cytokine εubfamily A (Cy 3 65
428291 AA534009 Hs 183487 interferon stimulated gene (20kD) 363
414883 AA926960 CDC28 protein kinase 1 363
428398 AI249368 Hs 98558 ESTs 363
428479 Y00272 Hs 334562 cell division cycle 2, G1 to S and G2 to 3 63
408482 NM.000676 Hs 45743 adenosme A2b rxeptor 363
404287 C6001909 gι|704441|dbj|BAA18909 1| (D298 363
431941 AK000106 Hs 272227 Homo εapienε cDNA FLJ20099 fiε, clone CO 361
414110 BE251752 gb 601112444F1 NIH_MGC_16 Homo sapiens c 361
427857 AL133017 Hs 2210 hypothetical protein FU22865 361
419968 X04430 Hs 93913 interieukin 6 (interferon, beta 2) 3 61
430413 AW842182 Hs 241392 small inducible cytokine A5 (RANTES) 360
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient, yeast, h 3 60 433001 AF217513 Hs 279905 clone HQ0310 PRO0310p1 360
430994 AA490346 Hs 40530 Homo sapiens, clone MGC 17624, mRNA, com 360
456534 X91195 Hs 100623 phospholipase C, beta 3, neighbor pseudo 359
437340 AL353935 Hs 135917 hypothetical protein DKFZp761D1823 3 59
435793 AB037734 Hs 4993 KIAA1313 protein 359
437016 AU076916 Hs 5398 guanine monphosphate synthetase 359
420247 AA256930 Hs 44680 hypothetical protein FLJ20979 358
424308 AW975531 Hs 154443 minichromosome maintenance deficient (S 357
422282 AF019225 Hs 114309 apolipoprotein L 357
424635 AA420687 Hs 115455 Homo sapienε cDNA FLJ 14259 fis, clone PL 357
421044 AF061871 Hs 101302 Human DNA sequence from clone RP1-238D15 357
408015 AW136771 Hs 244349 epidermal differentiation complex protei 356
422956 BE545072 Hs 122579 ECT2 protein (Epithelial cell transformi 356
449039 AI962602 Hs 74284 hypothetical protein MGC2714 356
446269 AW263155 Hs 14559 hypothetical protein FLJ10540 355
400297 AI127076 Hs 306201 hypothetical protein DKFZp56401278 355
428977 AK001404 Hs 194698 cyclin B2 355
402995 NM_002463* Homo εapienε myxoviruε (mflu 355
416065 BE267931 Hs 78996 proliferating cell nuclear antigen 354
432917 NM 014125 Hε 241517 PRO0327 protein 354
439750 AL359053 Hε 57664 Homo εapienε mRNA full length insert cDN 353
445411 AL137255 Hs 12646 hypothetical protein FLJ22693 3 52
438113 AI467908 Hs 8882 ESTs 352
414420 AA043424 Hs 76095 immediate early response 3 3 51
419682 H13139 Hs 92282 paired like homxdomam transcnption fa 350
447208 BE315291 Hs 237971 hypothetical protein MGC5627 3 50
432543 AA552690 Hs 152423 Homo sapiens cDNA FLJ21274 fis, clone C 349
442295 AI827248 Hs 224398 Homo sapienε cDNA FLJ 11469 fis, clone HE 349
426440 BE382756 Hs 169902 εolute camerfamily 2 (facilitated glu 349
429249 X81479 Hs 2375 egf like module containing, mucin-like, 348
413900 AW409747 Hs 75612 εtress induced-phosphoprotein 1 (Hsp70/H 348
424242 AA337476 Hs 347408 hypothetical protein MGC13102 348
414761 AU077228 Hs 77256 enhancer of zeste (Drosophila) homolog 2 347
446480 NM.014578 Hs 15114 ras homolog gene family, member 346
414825 X06370 Hs 77432 epidermal growth factor rxeptor (avian 346
428865 BE544085 Hs 164960 BarH like homeobox 1 346
449003 X76342 Hs 389 alcohol dehydrogenase 7 (class IV), mu o 346
450506 NM 004460 fibroblast activation protein, alpha 346
421307 BE539976 Hε 103305 Homo sapiens mRNA, cDNA DKFZp434B0425 (f 345
422938 NM.001809 Hs 1594 centromere protein A (17kD) 345
405545 Target Exon 345
418322 AA284166 Hs 84113 cyclm-dependent kinase inhibitor 3 (CDK 344
441703 AW390054 Hs 192843 leucine zipper protein FKSG14 344
417944 AU077196 Hs 82985 collagen, type V, alpha 2 344
417924 AU077231 Hs 82932 cyclin D1 (PRAD1 parathyroid adeπomatos 344
431228 AB006746 Hs 198282 phospholipid scramblase 1 344
422363 T55979 Hs 115474 replication fxtor C (xtivator 1) 3 (38 343
440502 AI824113 Hs 78281 regulator of G-protein signalling 12 343
448741 BE614567 Hs 19574 hypothetical protein MGC5469 343
453922 AF053306 Hs 36708 budding uninhibited by benzimidazoles 1 343
406646 M33600 Hs 308026 major histxompatibility complex, claεε 342
413281 AA861271 Hs 222024 tranεcπption fxtor BMAL2 342
449101 AA205847 Hs 23016 G protein-coupled rxeptor 342
430890 X54232 Hs 2699 glypicaπ 1 341
422809 AK001379 Hs 121028 hypothetical protein FL) 10549 341
412429 AV650262 Hs 75765 GR02 oncogene 341
443211 AI128388 Hs 143655 ESTs 341
422209 AF005210 Hs 113222 chemokine (C-C motif) rxeptor 8 340
428303 AW974476 Hs 183601 regulator of G-protein signalling 16 339
421817 AF146074 Hs 108660 ATP-binding cassette, sub-family C (CFTR 339
428664 AK001666 Hs 189095 similarto SALL1 (sat (Drosophιla)-lιke 339
422101 AW404176 Hs 111611 πboεomal protein L27 339
457670 AF119666 Hs 23449 insulin rxeptor tyrosine kinase subεtra 338
437033 AW248364 Hs 5409 RNA polymeraεe I εubunit 337
425322 U63630 Hs 155637 protein kinaεe, DNA-xtivated, catalytic 337
417059 AL037672 Hs 81071 extracellular matnx protein 1 337
400298 AA032279 Hs 61635 six transmembrane epithelial antigen of 336
414812 X72755 Hs 7367 monokine induced by gamma interferon 336
436748 BE159107 Hs 159263 collagen, type VI, alpha 2 336
401797 Target Exon 336
428309 M97815 Hs 183650 cellular retinoic acid-binding protein 2 335
421563 NM.006433 Hs 105806 graπulysm 335
402294 Target Exon 334
414024 AA134712 Hs 22410 gb zm79g08 r1 Stratagene neuroepithelium 334
401961 NM.021626 Homo εapiens serine carboxypep 333
418462 BE001596 Hs 85266 integnn, beta 4 333
418867 D31771 Hs 89404 msh (Drosophila) homeo box homolog 2 333
424800 AL035588 Hs 153203 MyoD family inhibitor 333
412420 AL035668 Hs 73853 bone morphogenetic protein 2 333
404440 NM_021048 Homo sapiens melanoma antigen, 333
432398 AA307808 Hs 2979 trefoil factor 2 (spasmolytic protein 1) 333
421677 H64092 Hs 38282 ESTs 333
407792 AI077715 Hs 39384 putative secreted ligand homologous to f 3 32 449048 Z45051 Hs 22920 similar to S68401 (cattle) glucose indue 332
417197 AW994561 Hs 151777 eukaryotic translation initiation fxtor 332
429669 BE185499 Hs 2471 KIAA0020 gene product 332
409636 AA305729 Hs 18272 am o acid transporter system A1 332
429415 NM.002593 Hs 202097 procollageπ C-endopeptidase enhancer 332
405386 Target Exon 332
410274 AA381807 Hs 61762 hypoxia inducible protein 2 331
448275 BE514434 Hs 20830 kineεiπ like 2 331
418245 AA088767 Hε 83883 tranεmembrane, prostate androgen induced 331
452291 AF015592 Hε 28853 CDC7 (cell division cycle 7, S cerevisi 331
431830 Y16645 Hs 271387 small inducible cytokine subfamily A (Cy 331
422575 AK000546 Hs 118552 hypothetical protein FLJ20539 331
404171 NM.000636* Homo εapiens superoxide dismu 331
418464 R87580 Hs 144531 gb ym89h07 r1 Soares adult brain N2b4HB5 331
425566 AW162943 Hs 250618 UL16 binding protein 2 331
410226 AI831958 Hs 61053 hypothetical protem 330
432281 AK001239 Hs 274263 hypothetical protein FLJ10377 330
443247 BE614387 Hs 333893 c Myc target JP01 330
449717 AB040935 Hs 23954 cerebral cell adhesion molxule 330
428336 AA503115 Hs 183752 microsemmoprotein, beta 329
416111 AA033813 Hs 79018 chromatin assembly factor 1 , subunit A ( 329
420759 T11832 Hε 127797 Homo sapiens cDNA FLJ11381 fis clone HE 328
432336 NM.002759 Hs 274382 protein kinase, interferon inducible dou 328
405778 NM.005361 Homo sapiens melanoma antigen, 328
419488 AA316241 Hs 90691 nucleophosm /nucleoplaεmin 3 327
421150 AI913562 Hs 189902 ESTε 327
406400 kallikrein 8 (πeuropεin/ovaεm) (KLK8) 327
455813 BE141577 gb QV2-HT0083 071299 018-.11 HT0083 Homo 327
426064 BE387014 Hs 166146 Homer, neuronal immediate earty gene 3 327
458814 AI498957 Hs 170861 ESTs Weakly similarto Z195.HUMAN ZINC 327
458791 BE615453 Hs 346509 dedicator of cyto-kinesis 1 327
419551 AW582256 Hs 91011 anteπor gradient 2 (Xenepus laevis) hom 326
429002 AW248439 Hs 2340 junction plakoglobm 326
450000 AI952797 Hs 10888 hypothetical protein FLJ21709 325
407777 AA161071 Hs 71465 squalene epoxidase 325
419485 AA489023 Hs 99807 ESTs, Weakly similar to unnamed protein 325
426437 BE076537 Hs 169895 ubiquitin-conjugating enzyme E2L6 324
415701 NM 003878 Hs 78619 gamma-glutamyl hydrolase (conjugase fol 324
412817 AL037159 Hs 74619 proteasome (prosome, mxropain) 26S subu 324
447519 U46258 Hs 339665 ESTs 324
412561 NM 002286 Hs 74011 lymphxyte-activation gene 3 324
446528 AU076640 Hs 15243 nucleolar protein 1 (120kD) 324
423198 M81933 Hs 1634 cell division cycle 25A 323
415091 AL044872 Hs 77910 3-hydroxy-3-methy!glutaryl Coenzyme A sy 323
441085 AW136551 Hs 181245 Homo sapienε cDNA FLJ 12532 fis, clone NT 322
443071 AL080021 Hs 8986 complement component 1, q subcomponent 322
408901 AK001330 Hs 48855 hypothetical protein FLJ10468 322
425849 AJ000512 Hs 296323 serum/glucxorticoid regulated kinase 322
410275 U85658 Hs 61796 transcnption fxtor AP-2 gamma (activat 322
415817 U88967 Hs 78867 protein tyrosine phosphatase, rxeptor-t 321
409197 N54706 Hs 303025 chromosome 11 open reading frame 24 321
412641 M16660 Hs 74335 heat εh∞k 90kD protein 1, beta 321
413436 AF238083 Hε 68061 sphmgosine kinaεe 1 321
408636 BE294925 Hs 46680 CGI-12 protein 321
412115 AK001763 Hs 73239 hypothetical protein FLJ 10901 321
413142 M81740 Hs 75212 ornithme dxarboxylase 1 321
411573 AB029000 Hε 70823 KIAA1077 protein 320
428242 H55709 Hs 2250 leukemia inhibitory fxtor (cholinergic 319
409361 NM 005982 Hs 54416 sine xulis homeobox (Drosophila) homolo 319
435014 BE560898 Hs 10026 mitxhondπal πbosomal protein L17 318
401176 Target Exon 318
434551 BE387162 Hs 280858 ESTs, Highly similar to A35661 DNA excis 317
410310 J02931 Hs 62192 coagulation fxtor III (thromboplastm, 316
427584 BE410293 Hs 179718 v myb avian myeloblastosis viral oncogen 316
423725 AJ4O3108 Hs 132127 hypothetical protein LOC57822 316
452012 AA307703 Hs 279766 kinesm family member 4A 316
407289 AA135159 Hs 203349 Homo sapiens cDNA FLJ12149 fis, clone MA 315
409461 AA382169 Hs 54483 N myc (and STAT) interactor 315
433020 AI375726 Hs 279918 hypothetical protein 314
437915 AI637993 Hs 202312 Homo sapiens clone N11 NTera2D1 teratoca 314
426997 BE620738 Hs 173125 peptidylprolyl isomerase F (cyclophilin 314
420005 AW271106 Hs 133294 ESTs 314
426935 NM 000088 Hs 172928 collagen, type I, alpha 1 3 13
412270 AC005262 Hε 73797 guanine nucleotide binding protein (G pr 313
421975 AW961017 Hε 6459 hypothetical protein FLJ11856 3 13
427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid etaph 312
448140 AF146761 Hs 20450 BCM like membrane protein precursor 3 11
431722 AF161528 Hs 268049 hypothetical protein 311
427239 BE270447 Hs 174070 ubiquitin earner protein 311
413385 M34455 Hs 840 indoleamine-pyrrole 2,3 dioxygenase 310
439780 AL109688 gb Homo εapiens mRNA full length insert 310
422885 BE244068 Hs 121544 interieukin 12 receptor, beta 1 310
418090 U57059 Hs 83429 tumor nxroεiε factor (ligand) εuperfami 310 439755 AW748482 Hs 77873 B7 homolog 3 3 10
404170 NM.000636* Homo sapienε εuperoxide dismu 309
417370 T28651 Hs 82030 tryptophanyl tRNA synthetase 309
410006 AW732308 Hs 57783 eukaryotic translation initiation fxtor 309
446291 BE397753 Hs 14623 interferon gamma inducible protein 30 308
421155 H87879 Hs 102267 lysyl oxidase 308
441224 AU076964 Hs 7753 calumenin 308
424326 NM 014479 Hs 145296 disintegnn proteaεe 308
429413 NM 014058 Hs 201877 DESC1 protein 308
436251 BE515065 Hs 296585 nucleolar protein (KKE/D repeat) 308
446510 H58306 Hs 15165 retinoic acid induced 14 308
442620 C00138 Hs 8535 Homo εapienε mRNA for KIAA1668 protein 307
409637 AA323948 Hs 55407 Homo sapiens mRNA cDNA DKFZp434K0621 (f 307
426682 AV660038 Hs 2056 UDP glycosyltransferase 1 family, polype 307
448853 NM 012204 Hs 22302 general transcnption fxtor IIIC, polyp 307
453775 NM 002916 Hs 35120 replication factor C (activator 1) 4 (37 307
408915 NM 016651 Hs 48950 heptacellular carcinoma novel gene-3 pro 306
435505 AF200492 Hs 211238 interleukin 1 homolog 1 306
412577 Z22968 Hs 74076 CD163 antigen 306
410575 BE207480 Hs 6994 Homo sapiens cDNA FLJ22044 fis, clone H 306
416084 L16991 Hs 79006 deoxythymidylate kmase (thymidylate km 305
430393 BE185030 Hs 241305 estrogen responsive B box protein 305
447342 AI199268 Hs 19322 Homo sapiens, Similar to RIKEN cDNA 2010 304
451578 NM 016323 Hs 26663 cyclin E binding protein 1 304
444726 NM 006147 Hs 84981 interferon regulatory factor 6 304
447733 AF157482 Hs 19400 MAD2 (mitotic arrest deficient, yeast h 304
437741 BE561610 Hs 5809 putative transmembrane protein, homolog 304
442643 U82756 Hs 3991 PRP4/STK/WD splicing factor 304
429358 AB037825 Hs 200317 KIAA1404 protein 303
410068 AI633888 Hs 58435 FYN binding protein (FYB-120/130) 303
426746 J03626 Hs 2057 undine monophosphate synthetase (orotat 303
409154 U72882 Hs 50842 interferon induced protein 35 302
442173 N76101 Hs 8127 KIAA0144 gene product 302
447400 AK000322 Hs 18457 hypothetical protein FLJ20315 301
450962 BE535647 Hs 25723 Sjogreπ'ε syndrome/scleroderma autoantig 301
407634 AW016569 Hs 136414 UDP-GlcNAc betaGal beta-1,3-N acetylgluc 301
411387 AW842339 Hs 130815 hypothetical protein FLJ21870 301
438662 AA223599 Hs 6351 cleavage and polyadenylation specific fa 301
459107 AA811881 Hs 28505 ubiquitiπ-conjugatmg enzyme E2H (homolo 300
430287 AW182459 Hε 125759 ESTs, Weakly similar to LEU5_HUMAN LEUKE 300
416110 Z42262 Hε 322844 hypothetical protein DKFZp564A176 300
435523 T62849 Hε 11090 membrane spanning 4-domams, εubfamily A 300
448569 BE382657 Hs 21486 εignal tranεducer and xtivator of tranε 300
410268 AA316181 Hs 61635 εix transmembrane epithelial antigen of 300
400200 NM.002788* Homo sapiens proteasome (pros 300
403330 Target Exon 299
413833 Z15005 Hs 75573 centromere protein E (312kD) 299
403416 AI744626 KIAA0564 protein 297
403438 NM J31419* Homo sapiens molecule possess 296
447942 F12628 Hs 155470 hypothetical protein MGC16040 296
427722 AK000123 Hs 180479 hypothetical protein FLJ20116 295
414806 D14694 Hε 77329 phosphatidylseπne synthase 1 294
440086 NM 005402 Hs 288757 v-ral simian leukemia viral oncogene hom 294
429547 AW009166 Hs 99376 ESTs 293
419121 AA374372 Hs 89626 parathyroid hormone-like hormone 290
431890 X17033 Hs 271986 integπn, alpha 2 (CD49B, alpha 2 subuni 289
417259 AW903838 Hs 81800 chondroitin sulfate protxglycan 2 (vers 289
418203 X54942 Hs 83758 CDC28 protein kinase 2 286
441633 AW958544 Hs 112242 normal mucosa of esophagus spxific 1 286
423425 AA375756 Hε 14449 KIAA1609 protein 286
412851 AI826502 Hs 106149 ESTs 286
400664 NMJ02425 Homo sapiens matnx metallopro 286
454140 AB040888 Hs 41793 hypothetical protein FU 10474 285
435602 AF217515 Hs 283532 uncharxteπzed bone marrow protein BM03 285
421116 T19132 Hs 101850 retmol binding protein 1, cellular 284
432343 NM 002960 Hs 2961 SlOOcalcium-binding protein A3 283
423767 H18283 Hs 132753 F-box only protem 2 282
413476 U25849 Hs 75393 xid phosphatase 1, soluble 282
441801 AW242799 Hs 86366 ESTs 280
441565 AW953575 Hs 303125 p53 induced protein PIGPC1 280
416539 Y07909 Hs 79368 epithelial membrane protein 1 279
428959 AF100779 Hs 194680 WNT1 inducible signaling pathway protein 279
422947 AA306782 Hs 122552 G-2 and S phase expresεed 1 275
417849 AW291587 Hs 82733 nidogen 2 274
450434 AA166950 Hs 195870 hypothetical protein FU14991 273
430466 AF052573 Hε 241517 poly eraεe (DNA directed), theta 272
431448 AL137517 Hs 306201 hypothetical protein DKFZp56401278 271
424874 AA347951 Hs 326413 i Homo εapienε cDNA FLJ20812 fiε, clone AD 271
453633 AA357001 Hs 34045 hypothetical protein FLJ20764 271
447854 AW138454 Hs 11594 ESTs 271
427581 NM 01478E 1 Hε 179703 I KIAA0129 gene product 270
412636 NM.00441S desmoplakm (DPI DPII) 269
420576 AA297634 Hs 54925 KIAA1858 protein 268 442932 AA457211 Hs 8858 bromodomain adjacent to zinc finger doma 268
425071 NM 013989 Hs 154424 deiodmase, lodothyronme, type II 268
410491 AA465131 Hs 64001 Homo sapiens clone 25218 mRNA sequence 266
428698 AA852773 Hs 334838 KIAA1866 protein 264
451277 AK001123 Hs 26176 hypothetical protein FLJ10261 264
447347 AA570056 Hs 122730 ESTs, Moderately similarto KIAA1215 pro 264
429505 AW820035 Hs 278679 a disintegnn and metalloproteinase doma 263
406137 NM.000179* Homo sapiens mutS (E coli) h 263
419594 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 262
443054 AI745185 Hs 8939 yes-assxiated protein 65 kDa 259
452620 AA436504 Hs 119286 ESTs 259
420552 AK000492 Hs 98806 hypothetical protein 259
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 256
434517 AA635690 Hs 337251 hypothetical protein MGC2487 256
448454 NM 005879 Hs 21254 TRAF interxting protein 255
425776 U25128 Hε 159499 parathyroid hormone receptor 2 255
436238 AK002163 Hε 301724 hypothetical protein FLJ11301 254
440676 NM 004987 Hs 112378 LIM and seneεceπt cell antigen-like doma 254
425811 AL039104 Hs 159557 karyopheπn alpha 2 (RAG cohort 1 , impor 254
429113 D28235 Hs 196384 prostaglandm-endoperoxide synthase 2 (p 253
407804 AF228603 Hs 39957 plxkstnπ 2 (mouse) homolog 253
452679 Z42387 Hs 83883 transmembrane, prostate androgen induced 251
411908 L27943 Hs 72924 cytidine deamiπase 249
449230 BE613348 Hs 211579 melanoma cell adhesion molxule 248
430024 A1808780 Hs 227730 integnn, alpha 6 247
458079 AI796870 Hs 54277 DNA segment on chromosome X (unique) 992 246
425345 AU077297 Hs 155894 protein tyrosine phosphatase, non recept 245
423881 AK001720 Hs 134403 hypothetical protein FLJ10858 245
407853 AA336797 Hs 40499 diekkopf (Xenopus laevis) homolog 1 245
457819 AA057484 Hs 35406 ESTs, Highly similar to unnamed protein 244
408296 AL117452 Hs 44155 DKFZP586G1517 protein 242
413048 M93221 Hs 75182 mannose rxeptor, C type 1 240
403851 C5002154* gι|7299015|gb|AAF5421 1| (AE0 239
433745 AF075320 Hε 28980 hypothetical protein FLJ 14540 237
423903 M57765 Hs 1721 interleukin 11 2.37
427700 AA262294 Hs 180383 dual spxificity phosphatase 6 236
419373 NM 003244 Hs 90077 TG-interxting factor (TALE family homeo 232
426827 AW067805 Hs 172665 methylenetetrahydrofolate dehydrogenase 231
440282 BE262386 Hs 7137 clones 23667 and 23775 zinc finger prote 231
406974 M57293 gb Human parathyroid hormone-related pep 231
401924 ENSP00000246632* CDNA FLJ20261 fis, don 230
444190 AI878918 Hs 10526 cysteine and glycme-nch protein 2 229
420923 AF097021 Hs 273321 differentially expresεed in hematopoieti 229
436608 AA628980 down εyndrome cπtical region protein DS 228
427509 M62505 Hs 2161 complement component 5 rxeptor 1 (C5a I 227
434398 AA121098 Hs 3838 serum-induαble kinase 227
419490 NM 006144 Hs 90708 granzyme A (granzyme 1 , cytotoxic T-lymp 226
418030 BE207573 Hs 83321 neuromedm B 225
404927 Target Exon 225
438549 BE386801 Hs 21858 tπnucleotide repeat containing 3 224
409038 T97490 Hs 50002 small inducible cytokine subfamily A (Cy 223
411388 X72925 Hs 69752 desm∞ollin 1 221
445757 AW449065 Hs 13264 KIAA0856 protein 218
405069 NM_006212* Homo sapiens 6-phosphofructo- 217
414035 Y00630 Hs 75716 εeπne (or cyεteine) proteinase inhibito 216
443168 AI038653 Hs 50500 ESTs 215
444301 AK000136 Hs 10760 aspoππ (LRR claεε 1) 213
433345 AI681545 Hs 152982 hypothetical protein FLJ13117 211
426471 M22440 Hs 170009 transforming growth fxtor, alpha 210
445019 AI205540 Hs 281295 ESTs 208
402021 NM_031891 Homo sapiens cadhenn 20, type 207
431866 NM 012098 Hs 8025 angiopoietin like 2 205
454219 X75042 Hs 44313 v-rel avian reticuloendothelioεiε viral 204
409571 AA504249 Hs 187585 ESTε 203
450831 R37974 Hs 25255 ESTs 1 99
408353 BE439838 Hs 44298 mitxhoπdπal πbosomal protein S17 1 99
445960 AI268399 Hs 140489 ESTs, Weakly similar to LIN1_HUMAN LINE- 1 98
448356 AL120837 Hs 20993 high glucose-regulated protein 8 1 97
429732 U20158 Hs 2488 lymphxyte cytosolic protein 2 (SH2 doma 1 91
426850 BE247670 Hs 172766 MAP/microtubule affinity-regulating kina 1 90
427335 AA448542 Hs 251677 G antigen 7B 1 90
450649 NM 001429 Hs 25272 E1 A binding protein p300 1 88
418460 M26315 Hs 85258 CD8 antigen, alpha polypepbde (p32) 1 88
449523 NM 000579 Hs 54443 chemokine (C-C motif) rxeptor 5 1 88
416975 NM 004131 Hs 1051 granzyme B (granzyme 2, cytotoxic T-lymp 1 86
433226 AW503733 Hε 9414 KIAA1488 protein 1 86
413129 AF292100 Hε 104613 RP42 homolog 1 85
432606 NM 002104 Hs 3066 granzyme K (εeπne protease, granzyme 3, 1 85
446620 AA128808 Hs 179902 transporter-like protein 1 81
449008 AW578003 Hs 22826 tropomoduliπ 3 (ubiquitous) 1 79
433160 AW207002 Hs 134342 TASP for testiε-spxifio adπamycin senε 1 78
420802 U22376 Hs 1334 v yb avian myeloblastosis viral oncogen 1 77
423482 BE280172 Hε 129228 galactokinase 2 1 77 434370 AF130988 Hs 58346 xtodysplasm 1, anhidrotic receptor 1 76
419125 AA642452 Hs 130881 B-cell CLL/lymphoma 11A (zinc finger pro 1 75
425545 N98529 Hs 158295 Homo sapiens, clone MGC 12401, mRNA com 1 74
405102 C15001220* gι|4469558lgb|AAD21311 1| (AF 1 74
433201 AB040896 Hs 21104 KIAA1463 protein 1 73
420798 W93774 Hs 99936 keratin 10 (epidermolytic hyperkeratosis 1 65
437860 AA333063 Hs 279898 Homo sapienε cDNA FLJ23165 fiε, clone L 1 62
414961 U27266 Hs 927 myoεm binding protein H 1 61
428405 Y00762 Hs 2266 cfiolmergic rxeptor, nicotmic, alpha p 1 61 0 422170 AI791949 Hs 112432 anti-Mulleπan hormone 1 61
431846 BE019924 Hs 271580 uroplakin 1B 1 58
404468 C3000442* gι|11120696|ref|NP_068518 1| c 1 57
405779 NM.005367 Homo sapiens melanoma antigen, 1 55
441129 AA074904 Hs 296420 ESTs, Weakly similar to T18651 hypotheti 1 55 5 427244 AA402400 Hs 178045 ESTs 1 52
411411 AA345241 Hs 55950 ESTs, Weakly similar to KIAA1330 protein 1 52
417777 AI823763 Hs 7055 ESTs, Weakly similar to I78885 seπne/th 1 51
418367 AA326035 Hs 59236 hypothetical protein DKFZp434L0718 1 51
440340 AW895503 Hs 125276 ESTs 1 48 0 437162 AW005505 Hs 5464 thyroid hormone receptor coactivating pr 1 47
424750 D29956 Hs 152818 ubiquitin specific protease 8 1 46
429469 M64590 Hs 27 glycine dehydrogenase (decarboxylat g, 1 44
406374 C16001364gι|11067373|ref|NP_0676891| C 143
430606 BE266026 Hs 31476 Homo sapiens cDNA FLJ13872 fis, clone TH 1 40 5 404405 Target Exon 1 39
401258 NM 030932* Homo sapienε diaphanouε (Droε 1 38
433323 AA805132 Hs 159142 ESTε 1 36
427441 AA412605 Hs 343879 SPANX family, member C 1 33
444707 AI188613 Hs 41690 deεmocollm 3 1 31 0 409103 AF251237 Hs 112208 XAGE-1 protein 1 27
451106 BE382701 Hs 25960 N-MYC oncogene 1 27
434804 AA649530 Hs 348148 gb nε44f05 ε1 NCI.CGAP.Alv1 Homo εapienε 1 23
430686 NM 001942 Hs 2633 deεmoglem 1 1 21
429325 AW088739 Hs 243770 ESTε 1 19 5 406703 X13100 Hs 173084 myosin, heavy polypeptide 3, skeletal mu 1 03
418827 BE327311 Hs 47166 HT021 1 01
404104 C6001378*gι|1171748|sp|P46530|NOTC_BRAR 1 00
TABLE 46B 0 Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank xceεεion πumberε
Pkθv CAT Number Arcp^ioπ 5 413808 2905.1 AI570199 AI888812 AW867550 AI921557 AW469096 AI925581 AI679986 AW473623 BE841640 BF061525 AI445703 A1925072 AW863188
AW863076 BE841731 AW863167 BE841390 BE841365 BF374078 BE841760 BE841694 BE841769 AA335110 BE841692 BF374073 AA335204 BF374079 BE841713 AA335167 BE841584 A 868103 BE841645 BE841765 AI076336 AW867433 BF373831 BE841758 AW868911 AW863155 AW868847 BE841651 AA335145 BE841670 BF374260 BF374088 BE841661 BE841728 BI335729 BE841739 BE841663 AW863104 AA335201 AA335143 BF906965 AW867493 BE841505 BF374250 BE841766 BF373837 AW863191 BE841705 AW863154 AW868673 AW867311 AA335896 O BE841753 AW863407 BE937102 BF374252 BF374247 BF374255 BE841785 AW029590 AW131278 AI801021 AW058240 AW058400 AW029230
AW029432 AW130609 AW029128 AW130469 AI570155 AI620272 AW029259 AI801389 AI888662 AI926902 AI801799 AI610344 AI452852 AW131174 AI581069 AI225028 AI446689 AI923321 AI439430 AI801502 AI679707 AW028944 AI933684 AI801724 AI537779 AI354652 AI470250 AI536872 AI891151 AW868019 AW006034 AI702599 AA335192 AA335165 AA335189 AI933725 AW044393 AI888797 BE841677 BE841681
_ _ AA335141 AW008176 AA335223 AI888837 AW868622 AI803901 AW005718 AI538062 AI282258 AI580678 AI445803 AI445394 AI868168 5 AA335144 AI926349 AA335210 AA334919 AA335163 AA335216 AI678342 BF374135 AI932922 AA335214 AA335109 AI570325 AI452619 AI926109
AI453488 AI678606 AW869289 AW869211 BE841580 AI679368 AI888882 AI926170 BF508305 AW869315 AA334926 BE841712 AW026584 AA335200 BE841764 AV730339 AW474979 AI286344 AI446430 AI537612 AA335166 AW868051 AI679133 AI949520 BE841652 AI949532 BE937113 BE841789 BE841643AW130556 BE841761 AW868716AW868698 BE841669 BE937108AA335158AA335153AA335159AW867404 AW868692 BE841742 AW868711 AW867546 BE841699 AA335198 AA335146 AW868150 BE841660 T99129 BE841740 BE841714 AA335154 0 AW868815 BF373812BE841657BE841780AI440394AA335215AA335202AA335162AA335160AI801656AI678499BF374019AW130236
AI826057 AI572459 AI932773 AA335197 AI611752 AA335224 AI452592 AA335147 AA335149 AA334928 AA335114 AA335111 AI567048 AW029395 AI570326 BF373838 BE841691 BE841776 AW863485 BF374093 AW130376 BE841732 AI446393 AI446781 AW867547 AW029012 AA335227 AW869307 AW869350 AW868709 AW869407 AW005017 AI679252 AI925523 AW151553 AW863109 A1445917 AI799620 AI921607 AW008153 AI520957 AI610620 AI679828 AI868151 AI537839 AI679547 T28354 AI282567 AA335207 R83655 BF906963 AW131160 AI925626
65 AW029396 AW028445 AW008410 AW152586 AW008476 AI801040 AI453669 AI621200 AA334925 BF374069 BF374075 N53208 BF374246
AW868723 BE937150 AA955002 AW863338 BE841767 421582 13358.1 X00474 NM 003225 X52003 M12075 BI765761 AW950155 AI571948 B1760569 AA308400 AA568312 BI761955 AA507595 AA614579 AA614409
BF747698 BM142326 AA307578 AI925552 AA578674 AA582084 AW009769 AA514776 AA588034 BG271505 AA858276 BM142503 AW050700 AI307407 AI202532 AA524242 AI909772 A1970839 BG236516 AW750216 AA587613 AI909749 AI909751 AI910083 AA614539 R55292 AA507418
70 453331 16559.1 BG571303AA410586AA035018 BG572117 BG620022AA147247 BG005785 BG014448 R31981 H02668H12498 R36203 BF992089 R73999
T49904 R75732 BI057974T53681 AA147933 N50695 R68588 R25671 R31935 R25110 R36105 AK055628 BE157467 AW663674 AA190993 H01642 BF510304 AA626915 AA746952 AI161014 AA099554 BG572534 AI803329 AI809932 AI808765 AA411449 AI378760 AA976929 AI378620 AA909684 R75632 AI360919 AI350463 AW069127 AA411621 AA742532 H12451 BE208298 H03612 H12839 N58781 R75957 BF996484 AI240665 BF989591 BI056086 BG001590 BF107035
75 4 40066668877 0 0.00 M31126 450375 16559.3 BG570706 BG572749 AW606284 H04021 AA151166 AW954405 AA131254 BG056461 W46291 H01532 H04384 H03231 AA852876 H04410 H59605 BE157601 AA113758
415989 10194.1 BC013389 BC017398 AI023543 AA191424 AI267700 AI469633 AW958465 AW953397 AA172056 BE940298 BF909208 BF909980 BF095153 BG285837 AI720344 BF541715 AA355086 AA172236
80 4 42266999911 2 299777711..11 AK001536 AK056135 BM474813 BE887303 AK022914 AW581996 AW812945 BE882302 AA134266 BI043873 AA019433 BI862088 BM468657
AU128438 BE384458 AL353967 BI857117 BF686525 BI465223 BM460132 AU129877 BI222283 BG171592 BI043544 BG496295 BG750710 BI256542 BG108520 AU150719 AW510354 AI554256 AL353968 AA191092 BF132635 454241 685806.1 BE184942 BE184946AW238414 BE144666 452203 2630 1 BC014081 NM 000593 X57522 L21208 L21207 L21206 L21205 L21204 AL561404 AL546423 AL560492 AL556882 AL541576 AL550654 BI823519
BI770023 AL554969 BI489906 AI304693 AW295947 BM146642 X57521 BG820143 BE898390 F06770 F12630 BM423610 AL561518 BM009470 BG742981 AA279685 AA847441 AA313737 BF172639 BF897216 BF914190 BF903647 S70277 AI569694 AW073296 AI361433 AA564644 AA487429 BE858232 AA838610 AI539114 AI719375 AI829129 BG057675 AI423422 AU158860 BE300655 AW170777 AA586956 AL571889 AL556850 AL576404 AL582800 BI256544 BF342301 BG875994 AA054458 AA353161 AI940434 BE816522 AL577636 AI479650 AW150377 AU154395 AW951271 AI032220 AI819778 AI346733 AW771150 AW512525 AI249904 AA279809 AI352549 AW512517 BG056280 AA521222 BE271141 AL581932 AL541575 BI819184 AV660190 AL556475 AI620020 AW089888 AW079179 Z21518 AA687601 F04651 AI783961 T57198 AI433367 T78652 AL554968 AA365648 AL582619 BE874601 BF804669 AL574458 BM145502 AI266514 AI538823 AI475626 AA948210 AA884054 AA487637 AA031844 AA535221 AW794256 AW361447 BE788505 AI682892 AA830989 AA862356 AA653084 BM009154 AA135727 H05927 H23433 R42244 N79997 AW366665 AW366601 AA678742 AL556474 AA135770 BE774050 BF914200 H88457 AA627746 BI560216 BI753586 408660 105529 1 AW975281 AA664986 AA525775 AA056342 A1538978
400245 12188.1 X79449 BC017853 AL121035 BF196384 AW119044 A1028023 AW451110 AI971911 AW015069 AI079170 AI376367 AI264113 AA829646 AA737579
AA449679 AA740864 NM.001111 U18121 AL567297 BG773801 BF973874 AV687104 AA527579 AA843525 BE706355 AI074589 AI523475 BE890249 AW406263 BE074258 AV729485 BF809610 BG058619 AA677244 BE179838 AA622264 AI460106 AA740411 AI499168 AI078223 AI682923 BE696559 AW375385 AA788739 BG984978 Z40874 T17054 F09669 AW844043 U10439 BI711870 AW245957 AU158567 AA679305 AA679316 W72510 AI346029 BG059762 AW251062 AA132373 AI925621 AI860230 AI340172 AW192891 AI707980 AI094937 AI042115 AI200901 BE328452 AA644678 AA551209 BE351065 AA970761 N68609 AW002028 AA160826 AI422774 AW873114 AW073597 AW664483 AI218710 AW020550 AW190607 AI984545 A1871821 AI333970 AI452887 AI818335 AA398655 AI554424 AI274187 BE465703 AW512940 AW241366 AI923954 AA576649 AW168294 AA813181 AA912168 AI049738 AW514073 AA548255 AI569630 BE710031 AA244182 AI341697 AA563904 AI537990 AW517908 AW172943 Z39498 AI750294 AW150414 AI253293 BE825720 T31860 AW150775 D20310 AA1508S2 AU133933 BE781148 , AL038957 BF910979 AA352297 BG988142 AW372175 BF229106 AW866705 BE093482 BG990396 AI499917 AA054452 H05484 AI828502
BM467331 AU140570 AL135417 BF947202 AW391926 BE813418 BF998473T92021 BI021048 BM048783AW501366 AW501342AW501549 BE939021 BE707147 BE160974 BE305207 N49011 AA947119 AA678801 BE536876 AW897428 BG329648 BG818540 BE542344 BI919250 BI253018 AW130996 BE074249 BE895428 BI034862 BE083277 BF952166
414883 8371_2 AF274943 BG494894 AI719075 AA908783 AI935150 AI422691 AA910644 AA583187 BM272167 AI828996 AA527373 AW972459 AI831360 AA772418 AI033892 AA100926 AU154749 AI459432 AI423513 AI094597 AA740817 AI991988 AI090262 AI312104 BI256707 AA459522 AA416871 AI075239 AI339996 AA701623 AI139549 AI336880 AA633648 AI989380 AI362835 AA399239 AI146955 BF514270 N92892 A1348243 AI278887 AA459292 AI494230 BF507531 AI492600 AA962596 AW613002 AA293140 AA235549 BF108854 AA954344 N49682 AI457100 AW589407 AW300758 BE220715 BE220698 BE569091 BM009647 BF900351 AI537692 AI203723 AI857576 AA584410 AW371667 BM172363
414110 1634167 1 BE253764 BE250764 BE255757 BE251752 BE251925 450506 1529_1 U09278 NM 004460 U76833 AF007822 AL550894 BG203919 AL575714 AI478772 AW022667 AW613820 AI435793 AI051768 AI200109 AA436611 BG208151 AI446661 BG215551 BM449645 AW630055 BG620125 AL550932 AW471133 AU136648 BE925603 BF828688 455813 1515590.1 BE141577 BE141585 BE141587
439780 49082 1 AL109688 R23665 R26578
400200 3806 1 BC005265 BG176720 AW006027 BM352064 AW026316AI635822AI880584AI693769 AI092211 BI492387 A1400449 AW166297 BF939910
AA232282 AW021432 AI333893 AA494308 AA854899 AI436795 AW069256 AA682373 AI092748 AA993184 AI126077 AI081758 AI240686 AI261863 AI378423 AA465237 AI376096 AA035579 AI087306 AA448162 AA129977 AI090903 A1080686 AI288939 N330O4 AI801240 AW021546 AI370773 AI086064 AA669528 AI250053 AI870113 AA853181 AA858014 BG055562 BG939559 AW080765 AA032283 AW467587 H40506 D00762 NM 002788 AA641134 AI582295 AI417525 AI563975 AI093566 AI707743 AI290741 AW073417 BE875418 BM264076 BG876884 AI680535 AW854219 BE774635 AW854212 BG952443 AW854221 AW854208 BE156348 BE843056 AW858991 BE937569 BG878291 BG876450 AW819099 AI908570 AA449871 AU135228 BM478404 BF126296 AA375499 AA248473 412636 1438 1 M77830 NM 004415 AF139065 BG681115 BG740377 BI712964 BG000656 AA128470 BI438324 H27408 BE931630 BE167165 AW370827
AW370813 J05211 BG698865 BG740734 BG680618 BG739778 BI765807 BM353403 BM353248 AW177784 AW205789 AW951576 AW848592 BE182164 BF149266 BE940187 BI060445 BI060444 BF350983 BE720095 BE720069 BE715154 BE082584 BE082576 BE004047 AA857316 BI039774 BE713818 BE713548 AW170253 BE160433 BI039775 AW886475 BM462504 BE931734 BF149264 AA340777 BF381183 BG621737 AU127260 AW364859 BF993352 BG223489 BE819009 BF381184 BE715956 R58704 AA852212 AW366566 BI090358 BF087707 BE819046 BE819005 AA377127 BE073467 BE819069 BE819048 BI036306 BG990973 BI040954 BF919911 AU140155 AI951766 AI434518 AW804674 BF752969 BE837009 BE925826 BF149265 AW995615 BE814264 BI039782 AU140407 BE144243 BE709863 BF985642 BE001923 BF933510 AW265328 BG436319 BE182166 AW365175 AW847688 BE818280 AW177933 BF873679 AW178000 BE082526 BF476866 BF086994 BF592276 BE082507 BE082514 BE082505 BF873693 AW068840 AW847678 BF804153 AW365157 BE813930 BE002030 AW365153 BE184941 BF749421 BE184920 BF839562 BE184933 BF842254 BE698470 BE931048 BF999889 BF368816 BE184924 BE159646 BE714632 BE184948 BG986845 AA131128 AA099891 W39488 C04715 BF096124 BE865341 AW799304 AL603116 BE149760 BE705967 BE705966 BE705968 AW848723 AW376699 AW376817 AW376697 BG005097 BF751115 BE696084 AW848371 AW376782 AW848789 AW849074 AW361413 BF927725 BF094211 AW997139 BE865474 BE185187 BE156621 BE715089 BE713297 BE713298 BE179915 AW799309 BF872345 BF088676 BE705939 AW752599 BG005197 BF350086 BE715196 BE715155 BF752396 BF093817 BF831190 BF752409 BE006561 BG959922 BF094833 BF094748 BF094583 AW377699 AW607238 BE082519 AW377700 BF349467 A1190590 AI554403 AI392926 AU158477 BI467252 AU159919 AI760816 BF082516 AI439101 AA451923 AI340326 AI590975 BI791553 AI700963 AI142882 AA039975 AA946936 AA644381 BM314884 AA702424 AI417612 AW190555 AI220573 AI304772 AI270345 AI627383 AA552300 AI911702 AW166807 AI346078 W95070 AA149191 AA026864 AI830049 AW780435 AI078449 AI819984 AI858282 BI468588 AI860584 AI025932 AA026047 AA703232 AA658154 AA515500 AW192085 AA918281 T77861 AI927207 AI205263 BF082491 AW021347 AI568096 BE939862 AA088866 D12062 AA056527 AA782109 W19287 W02156 AW150038 AA022701 T87181 H44405 AI910434 BF082513 AI494069 AI270027 AI635878 AA128330 BG681425 BE706078 R20904 BG680059 BG676647 BF764409 AA026654 AV745530 BI762796 BG287391 AW798780 BE706045 BE926470 AW799118 BF087996 BE002273 AW879451 AI571075 BE067786 AV721320 A1022862 N29754 C03378 N84767 AA131077 H30146 BE714290 A1686869 AI568892 AI915596 AW105614 AI887258 AI538577 BE926474 BE067737 BG319486 AA247685 AW798883 AW103521 BF989173 AW860878 BE939707 BE185750 BE714064 BE713903 BE713868 BE713763 BG950164 BE713810 AW365151 BG955489 BE005272 BF915937 AW365148 AI905927 BF992780 AW853812 BG954443 BI770853 BG679406 BG740832 BG681087 BG698430 AA455100 T87267 BE696209 BE696210 BI089483 BE006273 BE872225 AW391912 BE925515 BG677012 BG741970 AA026480 BE705999 BG677157 BE009090 BG681378 BE712291 BG961498 BG678984 BI040941 AA337270 AW384371 AW847442 BI058659 BE813665 W95048 W25458 AW177786 AA025851 BE931733 BF154837 BG949393 BE714441 AW996245 BE711801 AI284090 BE064323 BE719390 BE940148 BG991212 BF375714BF349522 BG996267 T48793 BI013292 BE001925 AW365156 AW365154 AW606653 BF763109 BE931637 BE167181 BE713879 BF354008 BF678726 H90899 AW365145 W38382 AI498487 436608 32229.2 BC015981 AJ301615 AA628980 AI126603 BF184719
TABLE 46C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495 Strand Indicates DNA strand from which exons were predicted
NLpoεition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 401781 7249190 Minus 83215-83435,83531-83656,83740 83901,8423 401780 7249190 Minus 28397-28617,28920 29045,29135-29296,2941
400666 8118496 Plus 17982-18115,20297-20456
401785 7249190 Minus 165776-165996,166189 166314,166408-16656
401747 9789672 Minus 118596-118816,119119 119244,119609 11976
400665 8118496 Pluε 16879-17023
402994 2996643 Minus 4727-4969
402075 8117407 Plus 121907-122035,122804-122921,124019-12416
405770 2735037 Plus 61057-62075
401994 4153858 Minus 42904-43124,43211-43336,44607-44763,4519
404996 6007890 Plus 37999 38145,38652-38998,39727-398724055
404240 5002624 Minus 116132-116407,116653-116922
402447 9796640 Plus 47605-47729,51696-51821,52070-52257,5330
402992 7767907 Minus 42137-42515
402408 9796239 Minus 110326-110491
404286 2326514 Plus 51086-51301
405387 6587915 Minus 3769 3833,5708 5895
404287 2326514 Plus 53134-53281
402995 2996643 Minus 5962-6216
405545 1054740 Pius 118677-118807,119091-119296,121626-12182
401797 6730720 Plus 6973-7118
402294 2282012 Minus 2575 3000
401961 4581193 Minus 124054-124209
404440 7528051 Plus 80430 81581
405386 6579238 Minuε 40959-41297
404171 9930793 Pluε 173667-173783,176876-177055
405778 7280331 Plus 18748-19757
406400 9256298 Plus 1553-1712,1878 2140,42524385,5922-6077
401176 9438469 Minus 20475-20734
404170 9930793 Plus 168836-169248
TABLE 47A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xceεεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
Rl Maximum of esophageal tumor Als divided by the 98th percentile of the normal eεophaguε Alε
Pkey ExAxn UnigenelD Unigene Title R1
400289 X07820 Hs 2258 matnx metalloproteinase 10 (stromelysin 31 70
411243 AB039886 Hs 69319 CA11 30 12
418007 M13509 Hs 83169 matrix metalloprotemase 1 (interstitial 1846
444325 AW152618 Hs 16757 ESTε 1822
444381 BE387335 Hs 283713 ESTε, Weakly similar to S64054 hypotheti 1752
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 1628
400666 NM_002425 Homo sapienε matnx metallopro 1559
425211 M18667 Hs 1867 progastπcsin (pepsinogen C) 1522
425679 X05997 Hs 159177 lipase, gaεtnc 1460
432239 X81334 Hs 2936 matnx metalloproteinaεe 13 (collagenase 13 14
431723 AW058350 Hs 16762 Homo sapiens mRNA, cDNA DKFZp564B2062 (f 1260
446619 AU076643 Hs 313 sxreted phosphoprotein 1 (osteopontin, 1200
453331 AI240665 ESTs 11 20
431620 AA126109 Hε 264981 2'-5'-olιgoadenylate synthetaεe 2 (69-71 1077
408380 AF123050 Hs 44532 diubiquitin 1032
423673 BE003054 Hs 1695 matnx metalloprotemase 12 (mxrophage 10 32
412326 R07566 Hs 73817 small inducible cytokine A3 (homologous 1022
419216 AU076718 Hs 164021 εmall inducible cytokine subfamily B (Cy 10 18
408243 Y00787 Hs 624 interleukin 8 980
414359 M62194 Hs 75929 cadhenn 11, type 2, OB-cadheπn (ostxb 975
450375 AA009647 a disintegnn and metalloprotemase doma 912
407366 AF026942 Hs 17518 gb Homo εapienε cιg33 mRNA, partial sequ 888
433447 U29195 Hs 3281 neuronal pentraxm II 864
421508 NM 004833 Hs 105115 absent in melanoma 2 846
452862 AW378065 Hs 8687 ESTs 834
432828 AB042326 Hs 287402 chondroitin 4-εulfotranεferase 792
452281 T93500 Hs 28792 Homo sapienε cDNA FLJ11041 fiε, clone PL 786
409757 NM 001898 Hs 123114 cyεtatm SN 762
452838 U65011 Hs 30743 preferentially expressed antigen in mela 760
413670 AB000115 Hs 75470 hypothetical protein, expressed in oεteo 758
452410 AL133619 Homo εapienε mRNA, cDNA DKFZp434E2321 (f 746
437330 AL353944 Hs 50115 Homo εapieπs mRNA, cDNA DKFZp761J1112 (f 744
406687 M31126 matnx metalloprotemase 11 (stromelysin 724
430280 AA361258 Hs 237868 interieukin 7 receptor 718
439343 AF086161 Hs 114611 hypothetical protein FLJ11808 713
429228 A1553633 Hε 326447 ESTs 704
421110 AJ250717 Hε 1355 cathepsin E 698
414004 AA737033 Hε 7155 ESTs, Moderately similar to 2115357A TYK 688
424321 W74048 Hs 1765 lymphxyte-spxific protein tyrosine kin 688
406673 M34996 Hs 198253 major histxompatibility complex, class 672
421582 AI910275 trefoil factor 1 (breast cancer, estroge 652 447164 AF026941 Hε 17518 Homo sapiens cιg5 mRNA, partial sequence 640
409403 AA668224 Hε 6634 Homo sapienε cDNA FLJ22547 fis, clone H 632
439926 AW014875 Hs 137007 ESTs 6 32
418460 M26315 Hs 85258 CD8 antigen, alpha polypeptide (p32) 6 12
411296 BE207307 Hs 10114 growth suppressor 1 603
426312 AF026939 Hs 181874 iπterferon-mduced protein with tetratπ 5 86
413441 AI929374 Hs 75367 Src-like-adapter 586
427337 Z46223 Hs 176663 Fc fragment of IgG, low affinity lllb, r 5 81
417715 AW969587 Hs 86366 ESTs 576
413808 J00287 Homo sapiens mRNA for caldesmon, 3' UTR 563
400665 NM.002425 Homo sapiens matrix metallopro 560
424408 AI754813 Hs 146428 collagen, type V, alpha 1 5 53
418299 AA279530 Hs 83968 integnn, beta 2 (antigen CD18 (p95), ly 5 44
444527 NM 005408 Hs 11383 small inducible cytokine subfamily A (Cy 542
428368 BE440042 Hs 83326 matnx metalloproteinase 3 (stromelyεin 540
416768 AA363733 Hs 1032 regenerating islet-denved 1 alpha (pane 5 38
430413 AW842182 Hs 241392 small inducible cytokine A5 (RANTES) 508
427509 M62505 Hs 2161 complement component 5 receptor 1 (C5a I 5 08
422530 AW972300 Hs 118110 bone marrow stromal cell antigen 2 504
413278 BE563085 Hs 833 interferon stimulated protein, 15 kDa 4 92
436856 AI469355 Hs 127310 ESTs 480
426711 AA383471 Hs 343800 conserved gene amplified in oεteoεarcoma 4 60
421362 AK000050 Hs 103853 hypothetical protein FLJ20043 453
452401 NM.007115 Hs 29352 tumor necrosis factor, alpha induced pro 448
404240 NM_018950 Homo sapiens major histocompat 436
435523 T62849 Hs 11090 membrane-εpanπing 4-domaιns, subfamily A 434
437763 AA469369 Hs 5831 tissue inhibitor of metalloproteinase 1 4 29
425139 AW630488 Hs 25338 protease, seπne, 23 424
415989 AI267700 ESTs 4 20
408202 AA227710 Hs 43658 DKFZP586L151 protein 4 11
450701 H39960 Hs 288467 hypothetical protein XP_098151 406
423271 W47225 Hs 126256 interleukin 1, beta 402
414774 X02419 Hs 77274 plasminogen activator, urokmase 396
443907 AU076484 Hs 9963 TYRO protein tyrosine kinase binding pro 3 90
424687 J05070 Hs 151738 matrix metalloprotemase 9 (gelatinase B 3 86
444006 BE395085 Hs 10086 type I tranε embrane protein Fn14 3 86
414915 NM_002462 Hs 76391 yxoviruε (influenza) resistance 1 , homo 376
408122 AI432652 Hs 42824 hypothetical protein FLJ 10718 349
408049 AW076098 Hs 345588 desmoplakm (DPI, DPII) 344
431629 AU077025 Hs 265827 interferon, alpha inducible protein (clo 3 37
435370 AI964074 Hs 225838 ESTs 329
443378 AW392550 Hs 9280 proteasome (prosome, mxropain) subunit 3 19
443071 AL080021 Hs 8986 complement component 1, q subcomponent, 3 18
409154 U72882 Hs 50842 interferon-induced protein 35 3 13
445417 AK001058 Hs 12680 Homo sapiens cDNA FLJ10196 fis, clone HE 3 12
413142 M81740 Hs 75212 ornithine dxarboxylase 1 300
406646 M33600 Hs 308026 major histxompatibility complex, clasε 276
402992 Target Exon 257
452304 AA025386 Hs 61311 ESTs, Weakly similar to S10590 cysteine 254
418245 AA088767 Hs 83883 transmembrane, prostate androgen induced 252
413945 NM 000591 Hs 75627 CD14 antigen 251
423225 AA852604 Hs 125359 Thy-1 cell εurfxe antigen 250
443883 AA114212 Hs 9930 εeπne (or cysteine) proteinase inhibito 248
415149 X12451 Hε 78056 cathepsin L 247
425247 NM 005940 Hε 155324 matnx metalloprote ase 11 (stromelyεm 246
410422 AL042014 Hs 63348 Homo εapienε, clone MGC 15203, mRNA, com 245
413936 AF113676 Hs 297681 εeπne (or cysteine) proteinase inhibito 245
409202 AA236881 Hs 51043 hexosaminidase B (beta polypeptide) 239
422562 AI962060 Hs 118397 AE-bindmg protein 1 235
443639 BE269042 Hs 9661 proteasome (prosome, macropain) subunit, 228
444652 BE513613 Hs 11538 xtin related protein 2/3 complex, subun 2 19
412471 M63193 Hs 73946 endothelial cell growth fxtor 1 (platel 2 19
449717 AB040935 Hs 23954 cerebral cell adhesion molxule 203
417389 BE260964 Hs 82045 midkine (πeuπte growth-promoting fxtor 203
428981 BE313077 Hs 93135 ESTε, Weakly similar to ALU2.HUMAN ALU S 1 83
445109 AF039916 Hs 12330 xtonucleoside tnphosphate diphoεphohyd 1 79
406778 H06273 Hs 101651 Homo sapiens mRNA, cDNA DKFZp434C107 (fr 1 70
408716 AI567839 Hs 151714 Homo sapiens mRNA for KIAA1769 protein, 1 69
412773 H15785 Hs 74573 similar to vxcima virus Hindlll K4L OR 1 66
414024 AA134712 Hs 22410 gb zm79g08 r1 Stratagene neuroepithelium 1 65
426530 U24578 Hs 278625 complement component 4A 1 58
414945 BE076358 Hs 77667 lymphxyte antigen 6 complex, Ixus E 1 52
TABLE 47B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT Number Accesεion 453331 16559.1 BG571303 AA410586 AA035018 BG572117 BG620022 AA147247 BG005785 BG014448 R31981 H02668 H12498 R36203 BF992089 R73999
T49904 R75732 BI057974 T53681 AA147933 N50695 R68588 R25671 R31935 R25110 R36105 AK055628 BE157467 AW663674 AA190993 H01642 BF510304 AA626915 AA746952 AI161014 AA099554 BG572534 AI803329 AI809932 AI808765 AA411449 AI378760 AA976929 AI378620 AA909684 R75632 AI360919 AI350463 AW069127 AA411621 AA742532 H12451 BE208298 H03612 H12839 N58781 R75957 BF996484 AI240665 BF989591 BI056086 BG001590 BF107035
450375 16558.3 BG570706 BG572749 AW606284 H04021 AA151166 AW954405 AA131254 BG056461 W46291 H01532 H04384 H03231 AA852876 H04410 H59605 BE157601 AA113758
452410 58661.1 AL133619 AI435410 AA622747 AW272464 AI215594 AI673758 AI476447 AI804128 AI581345 AI026826 AI300820 AW513621 AA256162 AI559724 AI493388 AA614641 AI125754 AI214351 AI567080 AI200813 AI476629 AI685732 AA602400 AA730140 AI565082 AI269603 AI807095 AA905453 AA505909 AI204595 AI582930 AI686077 AA757863 AA730154 AA664048 BI831663 AI734138 AI734130 AI732734 AW043563 AI741241 AI732741 BF111446 BE677727 AA437369 AA426284 AA433997 AA425820
406687 0 0 M31126
421582 13358.1 X00474 NM 003225 X52003 M12075 BI765761 AW950155 AI571948 BI760569 AA308400 AA568312 BI761955 AA507595 AA614579 AA614409 BF747698 BM142326 AA307578 AI925552 AA578674 AA582084 AW009769 AA514776 AA588034 BG271505 AA858276 BM142503 AW050700 AI307407 AI202532 AA524242 AI909772 AI970839 BG236516 AW750216 AA587613 AI909749 AI909751 AI910083 AA614539 R55292 AA507418
413808 2805.1 AI570199 AI888812 AW867550 AI921557 AW469096 AI925581 AI679986 AW473623 BE841640 BF061525 AI445703 AI925072 AW863188 AW863076 BE841731 AW863167 BE841390 BE841365 BF374078 BE841760 BE841694 BE841769 AA335110 BE841692 BF374073 AA335204 BF374079 BE841713 AA335167 BE841584 AW868103 BE841645 BE841765 AI076336 AW867433 BF373831 BE841758 AW868911 AW863155 AW868847 BE841651 AA335145 BE841670 BF374260 BF374088 BE841661 BE841728 BI335729 BE841739 BE841663 AW863104 AA335201 AA335143 BF906965 AW867493 BE841505 BF374250 BE841766 BF373837 AW863191 BE841705 AW863154 AW868673 AW867311 AA335896 BE841753 AW863407 BE937102 BF374252 BF374247 BF374255 BE841785 AW029590 AW131278 AI801021 AW058240 AW058400 AW029230 AW029432 AW130609 AW029128 AW130469 AI570155 AI620272 AW029259 AI801389 AI888662 AI926902 AI801799 AI610344 AI452852 AW131174 AI581069 AI225028 AI446689 AI923321 AI439430 AI801502 AI679707 AW028944 AI933684 AI801724 AI537779 A1354652 AI470250 AI536872 AI891151 AW868019 AW006034AI702599AA335192 AA335165 AA335189 AI933725 AW044393 AI888797 BE841677 BE841681 AA335141 AW008176 AA335223 AI888837 AW868622 AI803901 AW005718 AI538062 AI282258 AI580678 AI445803 AI445394 AI868168 AA335144 AI926349 AA335210 AA334919 AA335163 AA335216 AI678342 BF374135 AI932922 AA335214 AA335109 AI570325 AI452619 AI926109 AI453488 AI678606 AW869289 AW869211 BE841580 AI679368 AI888882 AI926170 BF508305 AW869315 AA334926 BE841712 AW026584 AA335200 BE841764 AV730339 AW474979 AI286344 AI446430 AI537612 AA335166 AW868051 AI679133 AI949520 BE841652 AI949532 BE937113 BE841789 BE841643 AW130556 BE841761 AW868716AW868698 BE841669 BE937108AA335158 AA335153 AA335159AW867404 AW868692 BE841742 AW868711 AW867546 BE841699AA335198AA335146AW868150 BE841660 T99129 BE841740 BE841714 AA335154 AW868815 BF373812 BE841657 BE841780 AI440394AA335215 AA335202AA335162 AA335160AI801656 AI678499 BF374019AW130236 AI826057 AI572459 AI932773 AA335197 AI611752 AA335224 AI452592 AA335147 AA335149 AA334928 AA335114 AA335111 AI567048 AW029395 A1570326 BF373838 BE841691 BE841776 AW863485 BF374093 AW130376 BE841732 AI446393 AI446781 AW867547 AW029012 AA335227 AW869307 AW869350 AW868709 AW869407 AW005017 AI679252 AI925523 AW151553 AW863109 AI445917 AI799620 AI921607 AW008153 AI520957 AI610620 AI679828 AI868151 AI537839 AI679547 T28354 AI282567 AA335207 R83655 BF906963 AW131160 AI925626 AW029396 AW028445 AW008410 AW152586 AW008476 AI801040 AI453669 AI621200 AA334925 BF374069 BF374075 N53208 BF374246 AW868723 BE937150 AA955002 AW863338 BE841767
415989 101941 BC013389 BC017398 AI023543 AA191424 AI267700 AI469633 AW958465 AW953397 AA172056 BE940298 BF909208 BF909980 BF095153 BG285837 AI720344 BF541715 AA355086 AA172236
TABLE 47C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495 Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
P"key Ret Strand NLposition
400666 8118496 Plus 17982-1811520297-20456
400665 8118496 Plus 16879-17023
404240 5002624 Minus 116132-116407,116653-116922
402992 7767907 Minus 42137-42515
TABLE 48A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 90th percentile of normal esophagus Als divided by the 90th percentile of esophageal tumor Als
Pkey ExAxn UnigenelD Unigene Title R1
407245 X90568 Hs 172004 titin 3743
426752 X69490 Hs 172004 titin 30 23
425545 N98529 Hs 158295 Homo sapiens, clone MGC 12401, mRNA, com 2369
407013 U35637 gb Human nebulin mRNA, partial eds 1709
400440 X83957 Hε 83870 nebulm 1556
406704 M21665 Hε 929 myoεin, heavy polypeptide 7, cardix muε 1421
428087 AA100573 Hε 182421 troponin C2, fast 1303
417070 Z19077 Hε 172004 titin 1302
406707 S73840 Hs 931 myosin, heavy polypeptide 2, skeletal mu 1261
405001 U58196 interleukin enhancer binding fxtor 1 1253
418391 NM 003281 Hs 84673 troponin I, skeletal, stow 1246
418205 L21715 Hs 83760 troponin I, skeletal, fast 1240
422633 X56832 Hs 118804 enolase 3, (beta, muscle) 1221
400499 C10001858 gι|6679124|reflNP_032759 1| πe 11 99
418390 AF133820 Hs 84665 titin immunoglobulin domain protein (myo 1053
412519 AA196241 Hs 73980 troponin T1, skeletal, slow 1021
417435 NM 005181 Hs 82129 carbonic anhydrase III, muεcle spxific 10 14
413778 AA090235 Hs 75535 myosin, light polypeptide 2, regulatory, 1013
408493 BE206854 Hs 46039 phosphoglycerate mutase 2 (muscle) 1000
416373 AA195845 Hs 73680 ESTs, Weakly similar to S12658 cysteme- 965
415672 N53097 Hs 193579 ESTs 9 57
409096 AA194412 Hs 50550 sarcomeπc muscle protein 948 431360 NM.000427 Hs 251680 loncrm 942
416982 J05401 Hs 80691 creatine kinase, mitochondnal 2 (sarcom 920
426429 X73114 Hs 169849 myosin binding protein C slow type 9 15
422069 AJ010063 Hs343603 tilin-cap (telethoπm) 896
409028 AB014513 Hs 49998 Z-band alternatively spliced PDZ-motif 864
437206 AW975934 Hs 283382 ESTs, Weakly similar to I38344 titin ca 848
421296 NM 002666 Hs 103253 penlip 847
412129 M21984 Hs 73454 troponin T3, skeletal, fast 839
434352 AF129505 Hs 86492 small muscle protem, X-lmked 828
418026 BE379727 Hs 83213 fatty acid binding protein 4, adipocyte 793
408591 AF015224 Hs46452 mammaglobm 1 788
435124 AA725362 Hs 120456 ESTs 776
430681 AW969675 Hs 291232 ESTs 770
454229 AW957744 Hs 278469 lacπmal proline rich protein 768
424734 AI217685 Hs 96844 ESTs 7 59
428221 U96781 Hs 183075 ATPase, Ca transporting, cardix muscle, 757
431204 F28841 Hs 250760 cytxhrome c oxidase subunit Via polypep 741
443727 Z25389 Hs 18459 ESTs 7 21
408753 AI337192 Hs47438 SH3 domain binding glutamic acid-πch pr 704
413132 NM 006823 Hs 75209 protein kinase (cAMP-dependent, catalyti 698
424485 AI685069 Hs 272556 peptidylargmiπe deiminase type I 693
403805 Target Exon 687
429997 NM 006789 Hs 227457 apolipoprotein B mRNA editing enzyme, ca 672
418532 F00797 Hs 85844 neurotrophic tyrosine kinaεe, rxeptor, 670
419711 C02621 Hs 159282 ESTε 670
422640 M37984 Hs 118845 troponin C εlow 668
433839 F35430 Hs 146070 ESTε, Weakly similar to ALU1_HUMAN ALU S 655
406703 X13100 Hs 173084 myosin, heavy polypeptide 3, skeletal mu 634
451621 AI879148 Hs 26770 fatty acid binding protein 7, brain 627
446962 AI351421 Hs 279709 muscle εpxific ring finger protein 1 620
411102 AA401295 Hs 23926 tπadiπ 6 17
411852 AA52810 Hs 107515 ESTε, Weakly similar to T00329 hypotheti 6 15
454059 NM 003154 Hs 37048 statheπn 595
451957 AI796320 Hs 10299 Homo sapiens cDNA FLJ13545 fis, clone PL 585
434360 AW015415 Hs 127780 ESTs 557
420813 X51501 Hs 99949 prolxtin-induced protein 552
417376 AA253314 Hs 154103 LIM protein (similar to rat protein kina 546
424688 AA216287 Hs1815 myosin, light polypeptide 3, alkali, ven 542
446523 NM.003063 Hs 334629 sarcolφin 541
402270 Target Exon 525
437846 AA773866 Hs 244569 esophagus cancer-related gene-2 524
424982 U94777 phosphorylaεe, glycogeπ, muscle (McArdle 5 17
414657 AA424074 Hs 76780 protein phosphatase 1, regulatory (mhib 514
410621 AA194329 Hs 172004 titin 5 10
429134 AA446953 Hs99004 ESTs 506
436519 AJ278124 Hs 238756 myozenm 504
447023 AA356764 Hs 17109 integral membrane protein 2A 503
427639 AW444530 Hs 105362 Homo sapienε, clone MGC 18257, mRNA, com 502
426451 AI908165 Hs 169946 GATA binding protein 3 (T-cell rxeptor 500
433635 AI074502 Hs 134292 hypothetical protein GC12921 498
429892 NM 003803 Hs 2504 myomesin 1 (εkelemm) (185kD) 496
411021 F00055 Hs 172004 -tan 495
416349 X69089 Hs79227 myomeειn (M-proteιn) 2 (165kD) 493
424897 D63216 Hs 153684 fnzzled-related protein 492
406741 AA058357 Hs74466 carcmoembryonie antigen-related cell ad 492
428824 W23624 Hs 173059 ESTε 478
418692 AK000268 Hs 87383 hypothetical protein 474
448406 AW772298 Hs 21103 Homo εapienε mRNA, cDNA DKFZp564B076 (fr 473
432306 Y18207 Hs 303090 protein phosphatase 1 , regulatory (mhib 466
424049 AB014524 Hs 138380 KIAA0624 protein 465
439609 AW971945 Hs 293236 ESTs 465
433122 AB019391 Hs 58049 ESTs 462
415447 Z97171 Hs 78454 my∞ilin, trabecular meshwork inducible 459
415655 W05433 ESTε 459
442376 W95588 Hε 129982 Homo εapienε cDNA FLJ 12228 fiε, clone MA 458
452308 AI167560 Hs 61297 ESTε 457
418072 F35210 Hs 86507 Human DNA εequence from clone RP3-353C17 456
429413 NM 014058 Hs 201877 DESC1 protein 453
423725 AJ403108 Hs 132127 hypothetical protein LOC57822 453
438704 AI435O60 Hs 32825 ESTε 450
413391 AI223328 Hs75335 glycine amidinotransferase (L-arginme g 448
430699 AW969847 Hs 292718 ESTs, Weakly similar to RET2.HUMAN RETIN 448
419050 NM 000036 Hs 89570 adenosiπe monophosphate deaminase 1 (iso 446
422313 AF045941 Hε 115166 sciellm 443
417045 F01180 Hs 332030 Homo sapienε ORF1 441
426158 NM 001982 Hs 199067 v-erb-b2 avian erythroblastic leukemia v 439
435101 AI743156 Hs 131064 ESTs 437
432408 N39127 ESTs, Weakly similar to A46010 X-lmked 435
439706 AW872527 Hs 59761 ESTε, Weakly εimilar to DAP1.HUMAN DEATH 435
429930 AI580809 Hs 99569 ESTε 430
429624 AA458648 Hs 99476 ESTε, Weakly similarto 1313184B alphal 426
429454 AL039940 Hs 202949 KIAA1102 protein 420
411000 N40449 Hs 201619 ESTs, Weakly similar to S38383 SEB4B pro 4 11 429852 AB010445 Hs 225948 small inducible cytokine subfamily A (Cy 3 99
428560 AI243209 Hs 98669 ESTs, Weakly similar to B47411 ADPπbosy 395
438328 AI492261 Hs 32450 ESTε 3 84
451917 AW391351 Hs 50820 Homo εapiens unknown mRNA 3 84
453876 AW021748 Hs 110406 ESTs, Weakly similarto I38022 hypotheti 383
414807 AI738616 Hs 77348 hydroxyprostaglaπdin dehydrogenase 15 (N 382
430171 AF086289 Hs 234766 skin spxific protein 3 80
422287 F16365 Hs 114346 cytxhrome c oxidase subunit Vila polype 375
446082 AI274139 Hs 156452 ESTε 3 74
449003 X76342 Hs 389 alcohol dehydrogenase 7 (clasε IV), mu o 370
431205 AA194560 Hs 250763 tropomodulin 4 (muscle) 3 68
443265 AI916207 Hs 9167 SH3 domain binding glutamic acid πch pr 368
424747 AA346241 Hs 231887 EST 3 67
410223 S73775 Hs 60708 calsequestπn 1 (fast twitch, skeletal m 363
423024 AA593731 Hs 325823 ESTs, Moderately similar to ALU5 HUMAN A 362
453817 AW755253 Hs 61920 ESTs 357
416431 AW384459 Hs 172004 Win 352
425971 AF135024 Hs 165296 kallikrein 13 349
412452 AA215731 Hs 79265 suppression of tumoπgenicity 5 348
421512 AB007923 Hs 265848 myomegalin 341
413922 AI535895 Hs 221024 ESTs 3 37
419648 T73661 Hs 91877 thyroid hormone responsive SPOT14 (rat) 3 36
418067 AI127958 Hs 83393 cystatm E/M 332
428666 AL080190 Hs 189242 Homo εapienε mRNA cDNA DKFZp434A202 (fr 3 29
451681 Z28564 Hs 255950 ESTε, Weakly similar to AA64_HUMAN 64 KD 3 26
420197 AW139647 Hs 88134 ESTs, Weakly similar to A57291 cytokine 3 23
425869 AA524547 Hs 160318 FXYD domain containing ion transport reg 321
404270 NM_006061 Homo sapienε specific granule 321
409169 F00991 Hs 50889 (clone PWHLC224) myosin light chain 2 3 17
426350 NM.003245 Hs 2022 transglutaminase 3 (E polypeptide prote 313
452023 AB032999 Hs 27566 KIAA1173 protein 308
417713 D42047 Hs 82432 KIAA0089 protein 299
435538 AB011540 Hs 4930 low density lipoprotein rxeptor related 297
450300 AL041440 Hs 58210 ESTs, Highly similar to ITH4 HUMAN INTER 297
451814 AA847992 Hs 137003 ESTs 283
452360 AI742082 Hs 98539 ESTs 267
431938 AA938471 Hs 54431 spxific granule protein (28 kDa), cyste 257
408104 AW972927 Hs 293968 ESTs 257
444329 W73753 Hs 209637 hypothetical protein FLJ12921 254
439652 W67826 Hs 55412 ESTs, Weakly similar to K1CJ.HUMAN KERAT 250
432191 AA043193 Hs 273186 hypothetical protein clone Telethon(lta 2 33
425855 AF135025 Hs 159679 kallikrein 12 232
430560 Z28942 Hs 243960 N myc downstream regulated gene 2 2 28
410677 NM 003278 Hs 65424 tetranxtiπ (plasminogen binding protein 225
411388 X72925 Hs 69752 des xollin 1 225
425721 AC002115 Hs 159309 uroplakin 1A 2 12
430520 NM 016190 Hs 242057 chromosome 1 open reading frame 10 2 10
429441 AJ224172 Hs 204096 hpophilin B (uteroglobin family member) 202
417405 W28657 Hs 5307 ESTs 201
434560 R13052 Hs 3964 Homo sapiens clone 24877 mRNA sequence 1 95
417074 Z49878 Hs 81131 guanidmoxetate N methyltransferaεe 1 79
430513 AJ012008 Hs 241586 G6C protein 1 68
454478 AW805749 Hs 318885 εuperoxide dismutase 2, mitochondnal 1 68
416559 AI039195 Hs 128060 ESTs 1 66
447205 BE617015 Hs 11006 ESTs, Moderately similar to T17372 plaεm 1 64
415780 U75898 Hs 78846 heat εhxk 27kD protein 2 1 55
409702 AI752244 eukaryotic translation elongation fxtor 1 50
TABLE 48B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank acceεεion numberε
Pkey CAT Number Acceεεion
407013 2073.7 U35637AA192323AA194508 BG011583 F25712AL596820 BE185376 424982 25362.1 AK057547 BG181248AA883756 F25670AA778128 F27657 F18914F25171 AA178844F21556 F25872 F20457F27617 F36059 F34817 F26967
F25922 F31278F34666 F01176 F36333 F01226 F27406 F27130 F28742 F24126 F29891 AA195955AA086351 W69291 F25880 F32791 F31311
F32380 F25216 F19679 F18656 F29700 F24954 F32741 F30404 F35470 F33989 F33141 F36382F34118 F17714AA176345 F24700AA550940
F18617 F16859 F15633 F34675 F16528 F17281 AA086388 F30859F21852 C02644 F29425 F25286 C03553F35259 W80691 F16457 F24094
F16783AA180319 F28443 F17763 F17448 F00542AA197179AA193012
415655 15499.1 AJ276240 N70563 F37502F29200 F27903 F18577 F19683 F20867Z28857 F30994 F31752F17375 F15601 F17543 F17411 432408 2061.18 AV724258AA247153 BF736219 BF513744AW058048AI082691 AA865520 N39127AV724549 F20776AA249747AW970392AA535433 F36964
F33894
409702 38388.1 AK056951 AK026458 BI439120 BM021106 F30243 BM055214 BM054962 BM069667 F37401 AA563621 AI752243 AI720773 AI933014 F18964
F35317 F35258 F27772 H39537 AW445222 F19408 H28557 F30608 F31797 F30960 BF837737 BF837688 AL551046 BI758668 BI765038 BI837440
BE392882 BI438801 AI093511 AI752244 AI784111 BG490221 BF338840 BF338974 BG896472 AL576843 AW966769 F25388 F37436 H28558
A1025548 AA782333 F30929 F36002 F21229 A1720539AA719449 F21231 F18924AA626886 F30774 F27704 F31411 F31127 F33381 F36153
F31793 F31138 F31966 F33901 AA298244 BI757347 AI810201 AI692843 F29441 H51409 F21804 AW973249 F18440 F17572 F32499 AA327152
AA534140 AI188088 F18893 F23362 AA010888 F18143 Z28500 H27651 AI720790 F22425 H13178 H28677 F21098 F37777 F21466 F16598
F23420 AL574723 R75610 F34035 F17845 F18560 F25902 R79117 F35534 F15713 AI612800 F16563 F15645 F33609 F29995 BG939623 F17385
F17384 F18660 F17922 F15523 AI093253 F18359 F31452 F00232 A1583430 BM021353 AA284108 H27650 H29935 BE708208 AA010737 H51451 Z19399 AI678418 AI952535 F17265 F17826 F37939 F35639 F17367 W75962 R70189 Z28755 R72106 AA335915 R75700 R79116 W72887 AI581552 R71403 F23388 C03913 BI756149 BI116109 BF790727 AL553994 R82966 W47487 AA456066 AW984608 BE708220 BG490537 W47419 TABLE 48C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489-495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
405001 6015406 Minus 104646-104819
400499 9796071 Minus 148495-148806 403805 8140491 Minus 51483-51742,53429-53511
402270 3108020 Plus 117656-117822
404270 9828129 Minus 3649-3750,4161-4306,5962-6049,68496965
Table 49A 1562 genes upregulated in lung cancer relative to normal body tissues
Table 49A shows 1562 genes upregulated in lung cancer relative to normal body tissues that are likely to encode proteins amenable to modulation by small moleculeε, peptideε, or antibodies These genes were selected from 59680 probeεetε on the Eos/Affymetnx Hu03 Genechip array Gene expresεioπ data for exh probeset obtained from this analysis was expresεed as average intensity (Al), a normalized value reflecting the relative level of mRNA expression The protein products of these genes often contain one or more domains indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death-domain, 7tm phosphatase, or lon.transporter) Certain predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar accesεion number, GenBank accession number
UniGenelD UniGene number
Pred Prot Domains Certain predicted protein domainε Abbreviationε used TM, transmembrane domain, SS, signal sequence =Y, very likely to contain =M, likely to contain other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280) UniGene Title UniGene gene title
R1 90th percentile of lung tumor Als divided by the 50th percentile of normal tissue Als, where the 15th percentile of normal tissue Ais was subtrxted from the numerator and denominator
Pkey, ExAccn, UnigenelD, Unigene Title, Pred Prot Domains, R1
421502, AF111856, Hε 105039, εolute earner family 34 (εodium phoεphate), member 2, Rιbosomal_L20,Na_Pι_cotrans,TM=Y„ 2406
439335, AA742697, Hs 62492, ESTs, Weakly similar to B39066 proline πch protein 15 - rat [R norvegicus], none,SS=M, 21 70
406621, X57809, Hs 181125, immunoglobulin lambda Ixus, ιg,HSP70,Ppx-GppA,TM=M„ 1936
421341, AJ243212, Hs 279611, deleted in malignant brain tumors 1, zona_pellucιda,CUB,SRCR,SS=M, 1699
452304, AA025386, Hs 61311, ESTs, Weakly similar to S10590 cysteine proteinase [H sapienε], none.none, 1667
429259, AA420450, Hs 292911, ESTs, Highly similar to S60712 band 6-proteιn [H sapienε], none.none, 16 50
454034, NM.000691, Hs 575, aldehyde dehydrogenase 3 family, member A1, aldedh,, 16 24
408000, L11690, Hs 620, bullous pemphigoid antigen 1 (230/240kD), efhand,εpxtπn,GAS2,SH3,Plxtιn,RA,Xylosejsom,FlιD,bZIP,Tropomyo8in,Myc-LZ,M,ldh_C,CH,AIP3,TM=M ,
1475 421798, N74880, Hε 29877, N xylsphmgoεine amidohydrolaεe (acid ceramιdaεe)-lιke, SAPA,Surfxtant_B,noπe, 14 18 439706, AW872527, Hs 59761, ESTs, Weakly similar to DAP1 HUMAN DEATH-ASSOCIATED PROTEIN 1 [H sapienε], none.none, 1394 431846, BE019924, Hs 271580, uroplakin 1B, transmembrane4,TM=Y,SS=M, 1354 417079, U65590, Hε 81134, interleukin 1 rxeptor antagonist, IL1,SS=M, 1297
444381, BE387335, Hs 283713, ESTs, Weakly similar to S64054 hypothetical protem YGL050w - yeast (Sxcharomyces cereviεiae) [S cereviεiae], Collageπ,TM=M,SS=M, 1292 408243, Y00787, Hε 624, interleukin 8, HLH,PAS,IL8,TM=M„ 1276 448133, AA723157, Hs 73769, folate rxeptor 1 (adult), Folate rec,MIP,TM=M,SS=M, 1250 414809, AI434699, Hs 77356, tranεferπn rxeptor (p90, CD71), PA,TM=Y„ 1212 436553, AW407157, Hs 181125, immunoglobulin lambda Ixuε, ιg,HSP70,Ppx-GppA,TM=M„ 1200 418738, AW388633, Hs 6682, solute earner family 7, (cationic ammo xid transporter, y system) member 11 , none,none, 11 99 419693, AA133749, Hs 301350, FXYD domain-containing ion tranεport regulator 3, ATP1G1_PLM_MAT8,TM=Y,SS=M, 11 88 417866, AW067903, Hs 82772 collagen, type XI, alpha 1, Col!agen,COLFI,TSPN,lamιnm_G,CorA,SS=M, 11 38 414998, NMJ02543, Hε 77729, oxidised low density lipoprotem (Ixtin like) rxeptor 1, lxtm_c,TM=Y,SS=M, 11 21 428970, BE276891, Hs 194691, retinoic xid induced 3, 7tm 3,TM=Y,SS=M, 11 08 418004, U37519, Hs 87539 aldehyde dehydrogenase 3 family, member B2, aldedh,TM=M,SS=M, 11 01 425397, J04088, Hs 156346, topoisomerase (DNA) II alpha (170kD), DNA_gyraseB,DNA_topoιsolV,HATPase_c,SS=M, 1069 418478, U38945, Hs 1174, cyclm-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), ank,, 1065 439223, AW238299, Hs 250618, UL16 binding protein 2, ldl_rxepLa,PKD,MHC_l,TM=M,SS=Y, 1052
441835, AB036432, Hs 184, advanced glycosylation end product-spxific rxeptor, homeobox,Acyltranεferase,notch,EGF,ank,Acyltransferase, 1047 451558, NM.001089, Hs 26630, ATP-binding casεette, εub-family A (ABC1), member 3, ABC_tran,SRP54,TM=Y,SS=M, 1033 443426, AF098158, Hε 9329, chromosome 20 open reading frame 1, noπe,TM=M„ 1021 452747, BE153855, Hs 61460, Ig superfamily receptor LNIR, ιg,Rhabd_glycop,TM=Y,SS=M, 10 14 417389, BE260964, Hs 82045 midkiπe (neuπte growth promoting fxtor 2), PTN_MK,TM=M,SS=Y, 10 13 433091, Y12642, Hs 3185, lymphxyte antigen 6 complex, Ixus D, UPAR_LY6,toxιn,Actιvιn_recp,TM=M,SS=Y, 1012 454098, W27953, Hs 292911 , ESTs, Highly similar to S60712 band 6-proteιn [H sapiens], none.none, 1005 414812, X72755, Hs 77367, monokine induced by gamma interferon, IL8,TM=M,SS=Y, 998 430832, AI073913, Hs 100686, ESTs, Weakly similar to JE0350 Aπteπor gradient 2 [H εapienε], none.none, 979 422310, AA316622, Hε 98370, cytxhrome P450, εubfamily IIS, polypeptide 1, none,pkιnaεe,fn3,ιg, 960 414987, AA524394, Hs 294022, hypothetical protein FLJ14950, SH2,TM=M„ 954 439453, BE264974, Hs 6566 thyroid hormone rxeptor iπteractor 13, AAA,ABC_traπ,CoaE,TM=M„ 952 430280, AA361258, Hs 237868 interleukin 7 receptor, fπ3,none, 948 423217, NM.000094, Hs 1640 collagen, type VII, alpha 1 (epidermdysis bullosa, dystrophic, dominant and recessive), Kuπιtz_BPTI,fn3 vwa,Oollagen,beta-lxtamase,TM=M,SS=M,
944 418882, NM.004996, Hs 89433 ATP-bmding casεette sub-family C (CFTR/MRP), member 1, ABC_membrane,ABC_tran,TM=Y,SS=M, 9 32 435472, AW972330, Hs 283022, tπggeπng rxeptor expressed on myeloid cells 1 , ιg,TM=M,SS=M 926 447343, AA256641, Hε 236894, ESTs, Highly similar to S02392 alpha-2-mxroglobulιn receptor precursor [H sapiens], none.none, 9 18
419508, AW997938, Hs 90786 ATP-binding casεette, sub-family C (CFTR/MRP), member 3, ABC.tran ABC_membrane,TM=Y,SS=M, 906 441384, AA447849, Hs 288660 Homo sapienε cDNA FLJ22182 fis, clone HRC00953, 7tm_3,none, 898 446292, AF081497, Hs 279682 Rh type C glycoprotein, Ammonιum_tranεp,FxCD,TM=Y,SS=M, 874 436972, AA284679 Hε 25640, claudin 3, PMP22_Claudιn,TM=Y,SS=M, 871 421817, AF146074, Hs 108660 ATP-binding casεette εub family C (CFTR/MRP) member 5, Fascιclιn,ABC_tran,ABC_membrane,GTP_EFTU,TM=M,SS=M, 871
423354, AB011130, Hs 127436, calcium channel, voltage dependent, alpha 2/deIta subunit 2, vwa.Cxhe TM=M„ 866 439606, W79123, Hs 58561, G protein coupled receptor 87, 7tm_1,TM=Y,SS=M, 863 438091, AW373062, , nuclear receptor subfamily 1, group I, member 3, hormone.rx.zf C4,noπe, 8 60 421506, BE302796, Hs 105097, thymidme kmase 1 , soluble, TK,TM=M„ 857 413278, BE563085, Hs 833, interferoπ-stimulated protein, 15 kDa, ubιquιtιn,SS=M, 856
408908, BE296227, Hs 250822, seπne/threoπine kinase 15, pkιnase,SS=M, 852 414774, X02419, Hs 77274, plasminogen activator, urokmase, kπngle,trypsm,planLthιonmε,SS=M, 849 430630, AW269920, Hs 2621, cystatin A (εtefin A), cystatιn,TM=M, 842 413011 , AW068115, Hs 821 , biglycan, LRR,LRRNT,SS=M, 840 446291, BE397753, Hs 14623 interferon, gamma inducible protein 30, GILT,TM=M,SS=Y, 839
411089, AA456454 , cell division cycle 2-lιke 1 (PITSLRE proteins), none.none 837 422765, AW409701, Hs 1578, bxuloviral IAP repeat-containing 5 (survivm), BIR,TM=M„ 834 453922, AF053306, Hε 36708, budding uninhibited by benzimidazoles 1 (yeast homolog), beta, noπe,SS=M, 825
449019, AI949095, Hs 67776, ESTs, Weakly similar to T22341 hypothetical protein F47B8 5 - Caenorhabditis elegans [C eleganε], none.none, 8 24 409799, D11928, Hs 76845, phosphoεenne phosphatase-like, Hydrolase,TM=M„ 822
416819, U77735, Hs 80205, pιm-2 oncogene, pkιnase,SS=M, 8 19 451541, BE279383, Hε 26557, plakophilin 3, Armadιllo_εeg,TM=M„ 8 16
409142, AL136877, Hε 50758, SMC4 (εtructural maintenance of chromosomes 4, yeast) like 1, ABC.tran M SMC_N,SMC_C,DUF164 none, 8 16 429002, AW248439, Hs 2340, junction plakoglobin, Ar adillo.seg TM=M„ 8 1 445033, AV652402, Hs 72901, mucin 13, epithelial transmembrane, ank,, 8 14
421757, Z20897, Hs 296259 parxxonase 3, Arylesterase,SS=Y, 810
414821 , M63835, Hs 77424, Fc fragment of IgG, high affinity la rxeptor for (CD64), ιg,TM=Y,SS=M 803 439285, AL133916, , hypothetical protein FLJ20093, ig.pkmase.LRR.LRRNT.LRRCT.noπe, 797
439738, BE246502, Hs 9598, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphoπn) 4B, Sema PSI,integπn_B,TM=Y, 786
424905, NM.002497, Hs 153704, NIMA (never in mitosis gene a) related kinase 2, pkιnase,TM=M„ 7 85 424779, AL046851, Hs 153053, CD37 antigen, transmembrane4,TM=Y,SS=M, 785
409340, BE174629, Hs 321130, hypothetical protein MGC2771, aa_permeases,pyπdoxal_deC,bromodomaιn,PHD,MBD,AT_h∞k,DDT,PI3_PI4_kιnase FAT FATC BolA,RUN,TM=M , 7 84 415323, BE269352, Hs 949, neutrophil cytosolic fxtor 2 (65kD, chronic granulomatous disease, autosomal 2), SH3,TPR,TM=M„ 773
427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lllb, rxeptor for (CD16), ιg,TM=Y,SS=M, 772 430378 Z29572, Hs 2556, tumor nxrosiε fxtor rxeptor εuperfamily, member 17, IL2,SS=M, 771 451253, H48299, Hε 26126, claudin 10, PMP22_Claudm,Peptιdase_M1,K_tetra,TM=Y,SS=M, 770 435575, AF213457, Hs 44234, tπggeπng rxeptor expresεed on myeloid cells 2, ιg,TM=Y,SS=M, 770 427747, AW411425, Hs 180655, seπne/threonine kinase 12, pkιnase,TM=M„ 770
426251, M24283, Hs 168383, intercellular adhesion molxule 1 (CD54), human rhmovirus rxeptoπ ιg,ICAM_N,TM=M,SS=M, 767 422282, AF019225, Hs 114309, apolipoprotein L, MotA_ExbB,TM=Y,SS=M, 764
413859, AW992356, Hs 8364, Homo εapiens pyruvate dehydrogenase kinase 4 mRNA, 3' untranslated region, partial sequence, SAM.PNT.none, 754 424008, R02740, Hs 137555, putative chemokine rxeptor, GTP-bindmg protein, 7tm_1,TM=Y,SS=M, 752 418322, AA284166, Hs 84113, cyclm-dependent kinase inhibitor 3 (CDK2-assocιated dual spxificity phosphatase), Y_phosphatase,DSPc,TM=M„ 746
421071, AI311238, Hs 104476, ESTs, Weakly similar to CGHU1E collagen alpha 1(XI) chain prxursor [H sapiens], none,TM=Y,SS=M, 740 421481, AW391972, Hs 104696, KIAA1324 protein, noπe,TM=M,SS=M, 739 438089, W05391 , , nuclear rxeptor subfamily 1 , group I, member 3, hormonejec zf-C4,none, 738 428484, AF104032, Hs 184601 , solute earner family 7 (cationic am o xid transporter, y system), member 5, aa_permeasx,pyπdoxal_deC,bramodomaιn,PHD,MBD,AT_hook,DDT,PI3_PI4_kιnase,FAT,FATC,BolA,RUN,TM=M„ 736
448988, Y09763, Hs 22785, gamma-aminobutyπc xid (GABA) A rxeptor, epsilon, Neur_chan_LBD,Neur_chan_memb,TM=Y,SS=M, 736 416178, AI808527, Hs 192822, serologically defined breast cancer antigen NY-BR-81, none,TM=M„ 731 418506, AA084248, Hs 85339, G protein-coupled rxeptor 39, none.none, 725 441553, AA281219, Hs 121296, ESTs, none,FG-GAP,ιntegπn_A, 725 422311, AF073515, Hs 114948, cytokine receptor-like fxtor 1, fn3,TM=M„ 721
415817, U88967, Hs 78867, protein tyrosine phosphataεe, receptor-type, Z polypeptide 1, fn3,Y_phosphatase,carb_aπhydrase,TM=Y,SS=M, 7 20 438746, AI885815, Hs 184727, Human melaπoma-asεxiated antigen p97 (melanotraπsferππ) mRNA, 3' flank, transferπn,Guaπylate_kιn,PDZ,SH3, 720 412723, AA648459, Hs 335951 , hypothetical protein AF301222, none,TM=M„ 7 14 418203, X54942, Hs 83758, CDC28 protein kinase 2, CKS„ 7 14 428582, BE336699, Hs 185055, BENE protein, none,TM=Y,SS=M, 7 12
418462, BE001596, Hs 85266, integπn, beta 4, fn3,ιntegπn_B,Calx-beta,EGF,TM=M,SS=M, 708 420344, BE463721, Hs 97101, putative G protein-coupled rxeptor; Methyltransf 5,TM=Y,SS=M, 702 428450, NMJ14791, Hs 184339, KIAA0175 gene product, KA1,pkιnase,TM=M„ 700
449230, BE613348, Hs 211579, melanoma cell adhesion molxule, ιg,ιεodh,Ribθ8omaU-6,F-box,TM=Y,SS=M, 698 438237, AW408158, Hs 318893, ESTs, Weakly similar to A47582 B-cell growth fxtor prxursor [H sapiens], Fuπn-lιke,pkιπase,Rxep_L_domaιπ,YLP,none, 697 421508, NMJ04833, Hs 105115, absent in melanoma 2, PAAD_DAPIN,HIN,TM=M„ 696 410342, R31350, Hs 743, Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide, ITAM,TM=Y,SS=M, 693 428479, Y00272, Hs 334562 cell division cycle 2, G1 to S and G2to M, pkιnase,ICE_p10,ICE_p20,TM=M,SS=M, 693 421532, AW138207, Hs 146170, hypothetical protein FLJ22969, Armadιllo_seg,HEAT,TM=M„ 691 451035, AU076785, Hε 430, plastm 1 (I isoform), efhand,CH,Adaptιn N,SS=M, 686
432407, AA221036, , gb zr03f12 r1 Stratagene NT2 neuronal prxursor 937230 Homo εapieπs cDNA clone 5' similar to SW POL.BAEVM P10272 POL POLYPROTEIN „ mRNA sequence, DEAD,helιcaεe_C,rrm,Ndr,Cy8_knot,TIL,vwa,vwc,vwd,IQ,Rlla abhydrolase.TGF- beta,DUF139,TPR,DSPc,tsp 1,Rιbosomal_S21,rvp,TM=M„ 684 442599, AF078037, Hs 324051, RelA-assxiated inhibitor, SH3,ank,TM=M„ 677 448243, AW369771, Hs 52620 integnn, beta 8, integnn.B.none, 676
427557, NM.002659, Hs 179657, plasminogen xtivator, urokmase rxeptor, UPAR_LY6,ET,PLA2_mh,SS=M, 675
418054, NM.002318 Hs 83354, lysyl oxidase like 2, SRCR,Lysyl_oxιdase,TM=M SS=M, 674
426440, BE382756 Hs 169902, solute camerfamily 2 (facilitated glucose transporter), member 1, sugar Jr,TM=Y,SS=M, 673 430397, AI924533, Hs 105607, bicarbonate transporter related protein 1, HC03_cotransp,TM=Y„ 671 449523, NM.000579, Hs 54443 chemokine (C-C motif) rxeptor 5, 7tm_1,TM=Y,SS=M, 671
431630, NM 002204 Hs 265829 integnn, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor), FG GAP.Rhabd glycop.mtegrin.A TM=Y,SS=M 670 410434, AF051152, Hs 63668, toll like rxeptor 2, LRR LRRCT,TIR,TM=M,SS=M, 669 424925, NM_002432, Hs 153837, myeloid cell nuclear differentiation antigen, PAAD_DAPIN,HIN , 6 69
431890 X17033, Hs 271986 integnn, alpha 2 (CD49B, alpha 2 subunit of VLA-2 rxeptor), vwa ιntegrιn_A,FG-GAP,TM=Y,SS=M, 665 428157, AI738719, Hs 198427, hexokiπase 2, hexokιnase,hexokιnase2,none, 664 430770, AA765694, Hs 123296 ESTs, none.none, 663
412270, AC005262, Hs 73797, guanine nucleotide binding protein (G protein), alpha 15 (Gq class), G-alpha arf,TM=M„ 659 439750, AL359053, Hs 57664 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 2005735, IMPDH_C,IMPDH_N,CBS,ιntegπn.B,Rιcιn_B_lectιn, 6 59 427700, AA262294, Hs 180383 dual specificity phosphataεe 6 Rhodanese,DSPc,TM=M„ 6 59 413048, M93221, Hs 75182, aπnose receptor, C type 1, fn2,lxtιn_c,Rιcιn_B_lxtιπ,Xlιnk,TM=Y,SS=M, 658 429345, R11141, Hε 199695 hypothetical protein, K_tetra,SAM, 658
416110, Z42262, Hs 322844, hypothetical protein DKFZp564A176, Sema,PSI,TIG,mtegπn_B,TM=Y,SS=M, 658 418883, BE387036, Hs 1211, xid phosphatase 5, tartrate resistant, MetaIlophos,TM=M SS=M, 657
426746, J03626, Hs 2057, undine monophosphate synthetase (orotate phosphoπbosyl transferase and orotidme 5'-decarboxylase) Pribosyltran.OMPdecase TM=M„ 6 57 402260, , , NM.001436* Homo sapiens fibπllaπn (FBL), mRNA transcript) (F8A), mRNA , pkinaεe.Fibnllaπn.none, 656
456373, BE247706, Hs 89751 , membrane-spanning 4-domaιns, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for, beta polypeptide), none,TM=Y„ 653 444006, BE395085, Hs 10086, type I transmembrane protein Fn14, ldl_recept_a,PKD,MHC_l,TM=M,SS=Y, 653 411027, AF072099, Hs 67846, leukxyte immunoglobulin-like rxeptor, subfamily B (with TM and ITIM domains), member 4, ιnosιtol_P,ιg,TM=M„ 652 435523, T62849, Hs 11090 membrane spanning 4-domaιns, subfamily A member 7, noπe,TM=Y,SS=M, 652 432920, U37689, Hs 3128, polymerase (RNA) II (DNA directed) polypeptide H, noπe,TM=M„ 648 412773, H15785, Hs 74573, similar to vxcinia virus Hindlll K4L ORF, PLDc,TM=M„ 648
409208, Y00093, Hs 51077, integπn, alpha X (antigen CD11C (p150), alpha polypeptide), vwa,FG-GAP,mtegπn_A,vwa,ιntegπn_A,FG GAP, 643 424441, X14850, Hs 147097, H2A hiεtone family, member X, hιεtone,CBFD_NFYB_HMF„ 643
418918, X07871, Hs 89476, CD2 antigen (p50), sheep red blood cell rxeptor, ιg,TM=Y,SS=M, 641
413219, AA878200, Hε 118727, Homo sapiens cDNA FLJ13692 fis, clone PLACE2000103, HLH,death,TNFR_c6,Acyl CoAJydro, 641 429170, NMJ01394, Hs 2359, dual specificity phosphatase 4, Rhodaπese,DSPc,Y_phosphatase,Rιboεomal_S3_N,TM=M„ 639 453914, NM.000507, Hs 574 fructoεe 1 ,6 biεphoεphatase 1 , FBPase,TM=M„ 6 37 424273, W40460, Hs 144442, phospholipase A2, group X, phoslιp,TM=M,SS=Y, 637
428385, AF112213 Hs 184062, putative Rab5-ιnteractιπg protein, SH2,SH3,SS=M, 636 432636, AA340864, Hs 278562, claudin 7, PMP22_Claudιn,TM=Y,SS=M, 634 409430, R21945, Hs 346735, splicing fxtor, arginine/senne-πch 5, DSPc.Rhodaπese.none, 634 451734, NM.006176, Hs 26944, neurogranin (protein kmase C substrate, RC3), IQ,7tm_1,TM=M , 634 443907, AU076484, Hs 9963, TYRO protein tyrosine kinase binding protein, πone,TM=M,SS=Y, 634
401027, , , Target Exon, none none, 626 418299, AA279530, Hs 83968, integnn, beta 2 (antigen CD18 (p95), lymphxyte function-asεxiated antigen 1, mxrophage antigen 1 (mac-1) beta subunit), ιntegπn_B,EGF,PSI,TM=Y,SS=M, 622 429732, U20158, Hs 2488, lymphxyte cytosolic protein 2 (SH2 domain-containing leukxyte protein of 76kD), SH2,SS=M, 621 408113. T82427, Hs 194101, Homo sapiens cDNA FLJ20869 fis, clone ADKA02377, 7tm_3,πone, 6 20
408771, AW732573, Hs 47584, potassium voltage gated channel, delayed rectifier, subfamily S, member 3, efhand,ιon_trans,K_tetra none, 6 19 456534, X91195, Hε 100623, phoεpholipase C, beta 3, neighbor pseudogene, LIM,PDZ,pkmase,SS=M, 6 18 408482, NM.000676, Hs 45743, adenosme A2b rxeptor, 7tm_1,TM=Y,SS=M, 6 17 426427, M86699, Hs 169840, TTK protein kinase, pkinase,, 617 445019, AI205540, Hs 281295, ESTs, none.none, 6 16
438552, AJ245820, Hs 6314, type I transmembrane rxeptor (seizure-related protein), none.none, 6 16
414907, X90725, Hs 77597, polo (Drosophιa)-lιke k ase, Rιbosoma!_L37ae,pkιna8e,POLO_box,tRNA-8ynL1b,dynamιπ dyπamιn_2,GED,bZIP,M„ 6 14 425322, U63630, Hs 155637, protein kinase, DNA-activated, catalytic polypeptide, PI3_PI4_kmase,FAT,FATC,TM=M„ 6 13 417421, AL138201, Hs 82120, nuclear rxeptor subfamily 4, group A, member 2, hormone_rx,zf-C4,SS=M, 6 13 425776, U25128, Hs 159499, parathyroid hormone rxeptor 2, 7tm 2,HRM,TM=Y,SS=M, 6 12
422278, AF072873, Hs 114218, fπzzled (Drosophila) homolog 6, Fz,Fπzzled,7tm_2,TM=Y,SS=M, 6 12 427490, Z95152, Hs 178695, mitogen xtivated protein kinase 13, pkιnase,TM=M„ 6 12 421445, AA913059, Hε 104433, Homo εapienε, clone IMAGE 4054868, mRNA, ιon_tranε,K_tetra,asp, 6 11
444143, AW747996, Hs 160999, ESTs, Moderately similar to A56194 thromboxane A-2 rxeptor, endothelial [H εapiens], Bcl-2,none, 6 10 423887, AL080207, Hs 134585, DKFZP434G232 protein, ABC_tran,TM=Y„ 6 10
409636, AA305729, Hs 18272, ammo xid transporter system A1, Aa_trans,TM=Y„ 609 411020, NMJ06770, Hε 67726, mxrophage rxeptor with collagenous structure, SRCR,Coilagen,TM=Y,SS=M, 609 425354, U62027, Hs 155935, complement component 3a rxeptor 1, 7tm_1,TM=Y,SS=M, 608
439963, AW247529, Hs 6793, platelet-activating fxtor xetylhydrolase, lεoform lb, gamma εubumt (29kD), PAF-AH_lb,Lιpase_GDSL,TM=M„ 607 421753, BE314828, Hs 107911, ATP-binding cassette, sub-family B (MDR TAP), member 6, ABC_tran,ABC_membrane,TM=Y,SS=M, 607
406908, Z25437, , gb H sapienε protein-tyroεme kinase gene, complete CDS , none.none, 607 425849, AJ000512, Hs 296323, serum/glucxorticoid regulated kinase, pkιnase,pkιnase_C,TM=M,SS=M, 606
452363, AI582743, Hε 94953, Homo εapienε, Similar to complement ∞mponent 1, q εubcomponent, o polypeptide, clone MGC 17279, mRNA, complete eds, C1q,CoIlagen,SS=M, 605 414883, AA926960, , CDC28 protein kmase 1, CKS„ 605
414166, AW888941, Hs 75789, N-myc downstream regulated, DEAD.helicaεe C,πτn,Ndr,Cyε_kπot,TIL,vwa,vwc,vwd,IQ Rlla.abhydrolaεe.TGF- beta,DUF139,TPR,DSPc,tεp_1,Rιboεomal_S21,rvp,TM=M„ 603 452888, AW955454, Hε 30942, ephπn-B2, Ephπn,fn2,TM=Y,SS=M, 603 448782, AL050295, Hε 22039, KIAA0758 protein, 7tm_2,ιg,GPS,SEA,TM=Y„ 603 449101, AA205847, Hs 23016, G protein-coupled rxeptor, 7tm_1,TM=Y,SS=M, 601
445462, AA378776, Hs 288649, hypothetical protein MGC3077, none,, 600 424381, AA285249, Hs 146329, protein kinase Chk2, pkιnase,FHA,DnaJ,TM=M , 600 420162, BE378432, Hs 95577, cyclm-dependent kinase 4, pkιπase,TM=M„ 599 439310, AF086120, Hs 102793, ESTs, caseιn_kappa,pkιnase,ιg,none, 597 414972, BE263782, Hs 77695, KIAA0008 gene product, GKAP,TM=M„ 597
425976, C75094, Hs 334514, NG22 protein, voltage_CLC,TM=Y,SS=M, 594
444946, AW139205, Hs 156457, hypothetical protein FLJ22408, abhydrolase,abhydrolase_2,TM=Y,SS=M, 593 411263, BE297802, Hε 69360, kinesm like 6 (mitotic centromere-asεxialed kinesm), kιnesιn,TM=M„ 593 421462, AF016495, Hs 104624, aquapoπn 9, MIP,TM=Y,SS=M, 592 426761, AI015709, Hs 172089, Homo sapiens mRNA, cDNA DKFZp586l2022 (from clone DKFZp586l2022), none,TM=Y,SS=M, 592
407792, AI077715, Hs 39384, putative sxreted ligand homologous to fjx1, πone,TM=M,SS=Y, 5 91 428771, AB028992 Hs 193143, KIAA1069 protein, C2,PI-PLC-Y,PI-PLC-X,TM= , 591 438564, AA381553, Hs 198253 major histxompatibility complex, class II, DQ alpha 1, ιg,MHC_ll_alpha,none, 591 440006, AK000517, Hs 6844, hypothetical protein FLJ20510, AAA.NB ARC,PAAD_DAPIN,NA,NA, 590 449027, AJ271216, Hs 22880, dipeptidylpeptidase III, Peptιdase_M49 EGF,ιg,Neuregulιn,TM=M„ 590 408790, AW580227, Hs 47860 neurotrophic tyrosine kmase, receptor, type 2 ιg,pkmase,LRR,LRRNT,LRRCT,TM=Y,SS=M, 589 413186, AU077141, Hε 75231, εolute camerfamily 16 (monocarboxylic xid transporters), member 1, εugar_tr,TM=Y,SS=M, 589 430696, AA531276, Hs 59509, ESTs, pkιnase,PP2C none, 588
422609, Z46023, Hs 118721 , εialidase 1 (lysosomal sialidase), BNR,SH2,SH3,pkιnase,TM=Y,SS=M, 588 425367, BE271188, Hε 155975, protein tyroεine phosphatase, receptor type, C-assxiated protein, none,TM=M,SS=Y, 588 429619, AL120751, Hs 211568 eukaryotic translation initiation factor 4 gamma, 1, none.none, 586 437429, H79981 , Hs 5613, Homo sapienε mRNA, cDNA DKFZp564E2222 (from clone DKFZp564E2222), SH2,SH3,BTB, 586 436576, AI458213, Hε 77542, ESTε, 7tm_1 ,DnaJ, 585
429663, M68874, Hs 211587, phospholipase A2, group IVA (cytosolic, calcium-dependent), C2,PLA2_B,TM=M„ 585 419981, AA897581, Hs 128773, ESTs, pkιnase,DAG_PE-bιπd,pkιnase_C,OPR,πone, 583
428953, AA306610, Hs 348183, tumor necrosiε factor rxeptor εuperfamily, member 6b, dxoy, 608_πbosomal,Rιbosomal_L10,TNFR_c6 DEAD,, 583 414806, D14694, Hs 77329, phosphatidylseπne synthase 1, PSS,TM=Y,SS=M, 582 451320, AW118072, , diacylglycerol kinase, zeta (104kD), none,TM=M„ 582
400991, , , Target Exon, Armadιllo_seg,lxtm_c,none, 581
456906, AF117646, Hs 156637, Cas-Br-M (munne) ectropic retroviral tranεformmg sequence c, zf-C3HC4,Cbl_N,Cbl_N2,Cbl_N3,TM=M , 581 434263, N34895, Hs 44648, ESTs, ig none, 581
428293, BE250944 Hs 183556, εolute earner family 1 (neutral ammo xid transporter), member 5, elF6,SDF,TM=M„ 578 421959, AW751497, Hs 98370, cytxhrome P450, subfamily IIS, polypeptide 1, p450,TM=Y,SS=M, 578
449539, W80363 Hs 58446, ESTs, pkinase.Fuππ like Rxep_L_domaιn,none, 577 409012, AL117435, Hs 49725, DKFZP434I216 protein, PH,RhoGEF,TM=M,SS=M, 577
412276, BE262621, Hs 73798, macrophage migration inhibitory factor (glycosylation inhibiting fxtor), MIF,sugar_tr,none, 575 409533, AW969543, Hε 21291, mitogen-xtivated protein kinaεe kinaεe kinase 13, Peptιdase_C48,noπe, 573 457001, J03258, Hε 2062, vitamin D (1,25- dihydroxyvitamin D3) rxeptor, hormone_reczf-C4,Metallothιo_5,TM=M„ 573
416084, L16991, Hs 79006, deoxythymidylate kinase (thymidylate kinase), none.none, 572
448569, BE382657, Hs 21486, signal transducer and activator of transcnption 1, 91kD, SH2,STAT,STAT_bιnd,STAT_prot,TM=M„ 572 452295, BE379936, Hs 28866, programmed cell death 10, serpin.none, 572
448775, AB025237, Hε 388, nudix (nucleoεide diphosphate linked moiety X) type motif 1 , NUDIX,TM=M,SS=M, 572 448733 NM.005629, Hs 187958, solute camerfamily 6 (neurotransmitter transporter, creatme), member 8, SNF,TM=Y„ 571 417015, M83772, Hs 80876, flavin containing mon∞xygenase 3, FMO lιke,pyr_redox,TM=Y,SS=M, 569 453323 AF034102, Hs 32951, solute carrier family 29 (nucleoside transporters), member 2, Nucleosιde_tran,TM=Y,SS=M, 569 410290, AA402307, Hε 322844, hypothetical protein DKFZp564A176, Sema PSI,TIG,ιntegπn_B,TM=Y,SS=M, 5 69 412182, AA205588, Hε 155160, Splicing fxtor, arginine/seπne πch, 46kD, rrm hormone_rx,zf-C4,sugar_tr„ 569 418526, BE019020, Hs 85838, solute earner family 16 (monxarboxylic acid transporters), member 3, none,TM=Y,SS=M, 566
447250, AI878909, Hs 17883, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform, PP2C,TM=M„ 565 438113, AI467908, Hs 8882, ESTs, 7tm_1,none, 565
421391, AW304350, Hε 191958, immunoglobulin superfamily rxeptor tranεtocatioπ aεεociated 2, ig.none, 564 417115, AW952792, Hs 334612, small nuclear ribonucleoprotein polypeptide E, Sm.pkmaεe,, 564 406137, , , NM.000179* Homo sapiens mutS (E coli) homolog 6 (MSH6), mRNA VERSION NM.000178 1 Gl, MutS_C,PWWP,MutS_N,TM=M„ 563 421917, AB028943, Hs 109445, KIAA1020 protein, BTB,zf-C2H2,PI3_PI4_kιnase,PI3Ka,TM=M„ 562 445873, AA250970, Hs 251946, poly(A)-bιndιng protein, cytoplasmic 1-lιke, PABP,rrm,pkιnase,14-3-3, 562 447365, BE383676, Hs 334, Rho guanine nucleotide exchange fxtor (GEF) 5, SH3,PH,RhoGEF,TM=M„ 561 446872, X97058, Hs 16362, pyπmidinergic rxeptor P2Y, G-protein coupled, 6, 7tm_1,TM=Y,SS=M, 559 433662, W07162, Hs 150826, CATX-8 protein, ras ABC_tran,arf,TM=M,SS=M, 559
449029, N28989, Hs 22891 , solute earner family 7 (cationic ammo xid transporter, y syεtem), member 8, aa_permeases,TM=Y,SS=M, 558 431236 AV656840, Hs 285115, interleukin 13 rxeptor, alpha 1, fn3,TM=Y,SS=M, 557 430508, AI015435, Hs 104637, ESTs, SDF,TM=Y,SS=M, 556
426227, U67058, Hε 154299, Human proteinaεe xtivated rxeptor-2 mRNA, 3'UTR, 7tm_1 ,TM=Y,SS=M, 555 421677, H64092, Hε 38282, ESTε, A1pp,Armadιllo segJBB, 554
429083, Y09397, Hs 227817, BCL2-related protein A1, Bcl-2,TM=M„ 554
429563, BE619413, Hs 2437, eukaryotic translation initiation fxtor 2B, subunit 5 (epsilon, 82kD), hexapep,W2,hormone2,DUF29,TM=M„ 552 412817, AL037159, Hs 74619, proteasome (prosome, mxropain) 26S subunit, non ATPase, 2, PC_rep,TM=M„ 551 452291 , AF015592, Hs 28853, CDC7 (cell division cycle 7, S cerevisiae, homolog)-lιke 1 , pkιπase,TM=M„ 551 437412, BE069288, Hε 34744, Homo εapienε mRNA, cDNA DKFZp547C136 (from clone DKFZp547C136), ABC_tran,GTP_EFTU,ABC_membrane,noπe, 550
423778, Y09267, Hε 132821, flavm containing mon∞xygenase 2, FMO lιke,pyr_redox,TM=Y,SS=M, 548 422846, BE513934, Hs 1583, neutrophil cytosolic fxtor 1 (47kD, chronic granulomatous disease, autosomal 1), SH3,PX,TM=M„ 548 434699, AA643687, Hs 149425, Homo sapienε cDNA FU11980 fiε, clone HEMBB1001304, Nucleosιde_tra2,none, 548 426691, NM_006201, Hs 171834, PCTAIRE protein kinase 1, pkιnase,TM=M„ 548 453905, NM_002314, Hε 36566, LIM domain kmase 1, pkmase,UM,PDZ,zf-PARP,TM=M„ 548
412939, AW411491, Hs 75069, eukaryotic translation elongation fxtor 1 gamma, none.none, 544 430486, BE062109, Hε 241551 , chloπde channel, calcium xtivated, family member 2, none,TM=Y,SS=M, 543 430066, AI929659, Hε 237825, signal recognition particle 72kD, TPR,AIRC,SAICAR_synt, 540 422241, Y00062, Hs 170121, protein tyrosine phosphatase, rxeptor type, C, kιnesιn,th3,Y_phosphatase,TM=M„ 540 411825 AK000334, Hs 72289, hypothetical protein FU20327, SNF,Zιp,TM=Y„ 536
400205, , , NM_006265* Homo sapiens RAD21 (S pombe) homolog (RAD21), mRNA (APO-1/CD95 (Fas)-aεεxιated phosphataεe) (PTPN13), mRNA , DUF173,SS=M, 535 410687, U24389, Hε 65436, lyεyl oxidaεe-like 1, Lysyl oxιdase,SS=M, 534 407786, AA687538, Hs 38972, tetraspan 1, transmembraπe4,TM=Y,SS=M, 534
425118, AU076611 , Hs 154672, methylene tetrahydrofolate dehydrogenase (NAD dependent), methenyltetrahydrofolate cyclohydrolase, myb DNA- bmdιng,THF_DHG_CYH,THF_DHG_CYH_C,CAP_GLY,AAA,LON,Peptιdase_C9,bZIP,M,xan_ur_permexe,HC03_cotransp,TM=M„ 532
400210, , , Eos Control, Adap_comp_sub,Clat_adaptor_ε,TM-M„ 532 414825, X06370, Hs 77432, epidermal growth fxtor rxeptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog), Fuπn lιke,pkιnase,Rxep_L_domaιn,TM=M,SS=M,
5 31 414035, Y00630, Hs 75716, seπne (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2, serpιπ,SS=M, 530 416000, R82342, Hε 79856, ESTε, Weakly similar to S65657 alpha-1 C-adrenergic rxeptor splice form 2 [H sapiens], none.sugar π 5 30
414368, W70171, Hs 75939, undine monophosphate kinase, PRK.CoaE,, 529 424321, W74048, Hs 1765, lymphxyte-spxific protein tyrosine kmase, SH2,SH3,pkιnase,TM=M„ 529 450296, AL041949, Hε 24756, hepatocyte growth factor-regulated tyrosine kmase subεtrate, none.none, 529 456672, AK002016, Hs 114727, Homo sapienε, clone MGC 16327, mRNA, complete eds, none,PK,PK_C,myosιn_head,RhoGAP, 528 410068, AI633888, Hs 58435, FYN-bindmg protein (FYB-120/130), SH3,TM=M„ 528
456629, AW891965, Hs 279789, histone deacetylase 3, HSP90,HATPase_c,zf-C2H2,PHD,πone 527
417218, AA005247, Hs 285754, met proto-oncogene (hepatocyte growth fxtor rxeptor), pkmase.Sema PSI.TIG ιntegrιn_B,TM=Y,SS=M 5 26
444051, N48373 Hs 10247, acbvated leucocyte cell adhesion molxule, none.none, 526 404083, , , C6002159* gι|628027|pιr||A53593 protem-tyrosiπe phoεphatase (EC 3 1 348), πoπreceptor ty, none,SS=M, 526 422051, AW327546, Hs 111024, solute earner family 25 (mitxhondπal earner; citrate tranεporter), member 1 , mιto_carr,TM=M„ 526 419034, NM.002110 Hs 89555, hemopoietic cell kinase, SH2,SH3,pkιπase,TM=M„ 526 427732, NM_002980, Hε 2199, εecretin rxeptor, 7tm_2,HRM,TM=M,SS-M, 525 425921, NM.007231 Hs 162211, solute carrier family 6 (πeurotransmitter transporter), member 14, SNF,TM=Y,SS=M, 525
448030, N30714, Hs 325960, membrane-spanning 4-domaιns, subfamily A member 4A, none,TM=Y,SS=M, 524 441607, NM.005010, Hs 7912, neuronal cell adhesion molxule, WD40,fn3,ιg,TM=M„ 5 23 446620, AA128808 Hs 179902, transporter-like protein, none,TM=Y,SS=M, 523 422616, BE300330, Hs 118725, selenophosphate synthetase 2, AIRS,AIRS_C,TM=M„ 523 447131, NM_004585, Hs 17466, retinoic xid receptor responder (tazarotene induced) 3, none,TM=Y„ 521
446272, BE268912 Hs 14601, hematopoietic cell-specific Lyn substrate 1, SH3,HS1_rep,TM=M„ 520 450447, AF212223 Hs 25010, hypothetical protein P15-2, NTF2,TM=M„ 5 19
425003, AF119046, Hs 154149, apurinic/apyπmidinic endonuclease(APEX nucleaεe) like 2 protein, Troponιn,Exo_endo_phos,IQ,TM=M„ 5 19 446636, AC002563, Hs 15767, citron (rho-mteractiπg, εeπne/thrxnme kinaεe 21), CNH,DAG_PE-bιnd,PH,lnvolucπn,M,TM=M„ 5 19 434826, AF155661 , Hs 22265, pyruvate dehydrogenase phosphatase, PP2C,none, 5 19
447081, Y13896, Hs 17287, potassium inwardly-rectifying channel, subfamily J, member 15, IRK,TM=Y„ 5 19
407949, W21874, Hs 247057, ESTs, Weakly similar to 2109260A B cell growth fxtor [H sapiens], RιbosomaLS14,aπk,pkιnase,death,πone, 5 18 442200, AW590572, Hs 235768, ESTs, none.none, 5 18
446566, H95741, Hs 17914, membrane-spanning 4-domaιns, subfamily A, member 6A πoπe,TM=Y,SS=M, 5 18 452690, AI536070 Hs 15085, ESTs, pou.homeobox lιg_chan,ANF_receptor, 5 18
419138, U48508, Hs 89631, ryanodine receptor 1 (skeletal), ιoπ_trans,SPRY,RYDR_ITPR,RyR,MIR,TM=Y„ 5 17 431441, U81961, Hε 2794, εodium channel, nonvoltage gated 1 alpha, ASC,TM=Y„ 5 16 418945, BE246762, Hs 89499, arxhidonate 5-lιpoxygeπase, lιpoxygenase,PLAT,TM=M„ 5 16 407601, AC002300, Hs 37129, sodium channel, nonvoltage-gated 1, beta (Liddle syndrome), ASC,TM=Y,SS=M, 5 15 429500, X78565, Hs 289114, hexabrxhion (tenascm C, cytotxtm), EGF,fn3,fibππogen_C,toxιn_2,Keratιn_B2,TM=M,SS=Y, 5 15
411984, NM.005419, Hs 72988, εignal transducer and activator of transcnption 2, 113kD, SH2,STAT,STAT_bιπd,STAT_prot,TM=M„ 5 15 433470, AW960564, , transmembrane 4 superfamily member 1, none,TM=Y,SS=M, 5 14 452817, AA322859, Hs 284275, Homo sapienε PAK2 mRNA, complete eds, pkιnase,PBD,TM=M„ 5 14 453102, NM_007197, Hs 31664, fnzzled (Drosophila) homolog 10, Fz,Fπzzled,7tm_2,TM=Y,SS=M, 5 14 427792, M63928, Hs 180841, tumor necrosis factor receptor εuperfamily, member 7, SRP14,TNFR_c6,SS=M 514
430563, AA481269, , ATP-binding cassette, sub-family C (CFTR/MRP), member 5, ABC_tran,GTP_EFTU,ABC_membrane,none, 5 13 431681, AK000378, Hs 267566, hypothetical protein FLJ20371, sugar_tr,TM=Y„ 5 12
431183, NMJM6855, Hε 250696, KDEL (Lyε-Aεp-Glu-Leu) endoplasmic reticulum protein retention receptor 3, ER_lumen_rxept,TM=M,SS=M, 5 12 417771, AA804698, Hs 82547, retinoic xid rxeptor responder (tazarotene induced) 1, none none, 5 11 418613, AA744529, Hs 86575, mitogen-xtivated protein kinase kinase kinase kinase 1, pkιπase,CNH,TM=M„ 5 11
409524, AW402151 , Hs 54673, tumor nxrosiε fxtor (ligand) superfamily, member 13, TNF,TM=Y,SS=M, 5 11 436856, AI469355, Hs 127310, ESTs, pkιnase,rπn,TM=M„ 509 411296, BE207307, Hs 10114, growth suppreεεor 1, 20G-Fell Oxy,TM=M,SS=M, 509 410082, AA081594, Hs 158311, Musashi (Drosophila) homolog 1, rrm,TM=M„ 509 404440, , , NM.021048 Homo sapiens melanoma antigen, family A, 10 (MAGEA10), mRNA VERSION NM.021049 1 Gl, MAGE,TM=M„ 508
424977, AA349289, Hs 100057, Homo εapienε cDNA FLJ22902 fis, clone KAT05581, none.none, 508 422100, AI096988, Hs 111554, ADP-πbosylation fxtor-like 7, arf,ras,TM=M„ 507 452222, AW806287, Hε 21432, SEX gene, Sema,TIG,PSI,GDI, 507 430300, U60805, Hs 238648, oπcostatin M receptor; fn3,TM=Y,SS=M, 507 408369, R38438, Hs 182575, εolute earner family 15 (H"? transporter), member 2, PTR2,TM=Y„ 507
422112, BE540240, Hs 111783, Lsm1 protein, Sm,BAG,SS=M, 506 449961, AW265634, Hε 133100, ESTε, pkιnaεe,Fuπn-lιke,Rxep L_domaιn,none, 506 430024, AI808780, Hs 227730, integπn, alpha 6, ιntegπn_A,FG-GAP,TM=Y,SS=M, 506 412641, M16660, Hs 74335, heat shxk90kD protein 1, beta, HSP90,HATPase_c,TM=M„ 505 437608, AA761605, Hs 292308, ESTs, Weakly similar to ALULHUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H εapienε], pkιπase,RI01,none,
505 400296, AA305627, Hs 139336, ATP-bmding cassette, sub-family C (CFTR/MRP), member 4, ABC_tran,ABC_membrane,TM=Y„ 504 446232, AI281848, Hs 194691, retinoic xid induced 3, 7tm_3,noπe, 504 425262, D87119, Hs 155418, GS3955 protein, pkmase,SS=M, 504 414703, BE243877, Hs 76941, ATPase, Na? transporting, beta 3 polypeptide, Na_K-ATPase,TM=Y,SS=M, 503
434808, AF155108, Hs 256150, Homo sapiens, Similarto RIKEN cDNA 2810027019 gene, clone MGC 14827, mRNA, complete eds, none,TM=M„ 503 425852, AK001504, Hs 159651, death rxeptor 6, TNF superfamily member 21, death,TNFR_c6,TM=Y,SS=M, 503 449437, AI702038, Hs 100057, Homo sapiens cDNA FLJ22902 fis clone KAT05581 , none.none, 503
448913, AA194422, Hs 22564, myosin VI, rrm,zf-RaπBP,pkιnase,GST_C,Ets,SAM_PNT,ABC2_membrane,myosιn_head,IQ,Myosιn_N,bZIP,zf- C2H2,PHD,BTB,TFIIS,AT hook,SAM,TM=M„ 502
413441, AI929374, Hs 75367, Src-like-adapter, SH2,SH3,TM=M„ 502
427618, NM.000760, Hs 2175, colony stimulating fxtor 3 rxeptor (graπulxyte), fn3,TM=M,SS=M, 502 417666, AI345001, Hs 82380, menage a trois 1 (CAK assembly fxtor), zf-C3HC4,TM=M„ 502 429903, AL134197, Hs 93597, cyclm-dependent kinase 5, regulatory subunit 1 (p35), CDK5_xtιvator,none, 501 445333, BE537641, Hs 44278, hypothetical protein FU12538 similarto ras-related protein RAB17, raε,arf,TK,SS=M, 501
426285, U20620, Hs 343581, karyopheπn alpha 1 (importin alpha 5), Armadιllo_seg,IBB,TM=M„ 501 421233, AA209534, Hε 284243, tetraεpan NET-6 protein, traπsmembrane4,TM=Y,SS=M, 501
424517, AI539443, Hs 137447, Homo sapiens cDNA FU12169 fis, clone MAMMA1000643, SH2,STAT,STAT_bιnd,STAT_prot,πone, 500 425345, AU077297, Hs 155894, protein tyrosine phoεphatase, non-rxeptor type 1 , Y _phosphatase,DSPc,TM=M,SS=M, 500 446946, AI878932, Hε 317, topoiεomerase (DNA) I, Topoιsomerxe_l,Topoιsomer_l_N,RrnaAD,Hanta_nuclexap,TM=M„ 499
413900, AW409747, Hs 75612, stress-induced phosphoprotein 1 (Hsp70/Hsp90-organιzιng protem), TPR,PDZ,WW,Guanylate_kιn,TM=M„ 498 412116, AW402166, Hs 784, Epste -Barr virus induced gene 2 (lymphxyte-spxific G protein-coupled rxeptor), 7tm_1,TM=Y,SS=M, 498 400792, AA635062, , Homo sapiens mRNA, cDNA DKFZp434O0515 (from clone DKFZp434O0515) zf-C3HC4,CARD,BIR,TM=M„ 498 417018, M16038, Hs 80887, v-yes-1 Yamaguchi εarcoma viral related oncogene homolog, SH2,SH3,pkιnase,TM=M„ 498 427247, AW504221, Hs 174103, integnn, alpha L (antigen CD11A (p180), lymphxyte function-assxiated antigen 1, alpha polypeptide), vwa ιπtegππ_A,FG-GAP,TM=Y,SS=M, 4 £
442080, AW444761, Hs 44565, ESTε, ank,, 497
454042, H22570, , hypothetical protein FLJ20093, ιg,pkmaεe,LRR,LRRNT,LRRCT,πone, 497 452698, NM.001295, Hε 301921, chemokine (C-C motif) rxeptor 1, 7tm_1,TM=Y,SS=M, 496 416276, U41060, Hs 79136, UV-1 protein, estrogen regulated, Peptιdase_C4,Oεteopontιn,Zιp,TM=Y,SS=M, 496 408847, AW290997, Hs 30348, ESTs, pkιnase,ιg,πoπe, 496
419452, U33635, Hs 90572, PTK7 protein tyrosine kinase 7, ιg,pkιnase,TM=Y,SS=M, 495
450737, AW007152, Hs 203330, ESTs, trypsιn,ldl_rxepLa,none, 495
443354, AW970672, Hε 9247, protein kinase, AMP-activated, alpha 1 catalytic subunit pkιπase,RI01,TM=M„ 494
Figure imgf000571_0001
424099, AF071202, Hs 139336, ATP-binding caεεette, sub-family C (CFTR/MRP), member 4, ABC_tran,ABC_membrane,TM=Y„ 470 424959, NM.005781, Hs 153937, activated p21cdc42Hs kinaεe, ldh,ldh_C,SH3,pkιnase,UBA,TM=M„ 470 427206, NM.004586, Hs 173965, πbosomal protein S6 kinase, 90kD, polypeptide 3, none.none, 470
421662, NM.014141, Hε 106552, cell recognition molxule Caεpr2, EGF,F5_F8_type_C,lamιnιn_G,Sulfate_traπsp,STAS,7tm_3,xan_ur_permease,TM=Y,SS=M, 470 413431, AW246428 Hs 75355, ubiquitin-coπjugating enzyme E2N (homologous to yeast UBC13), UQ_con,TM=M„ 470
405484, , , C3002124* gι]12737280|ref]XP_0066822| keratin 18 [Homo sapιenε]||6633, none,SS=M, 470 401345, M83738, , protein tyroεine phosphatase, non rxeptor type 9, none,TM=M„ 470 416602, NM_006159, Hs 79389, nel (chicken) like 2, EGF,vwc,TSPN,SS=Y, 469 412507, L36645, Hs 73964, EphA4, fn3,pkιnase,SAM,EPH lbd,TM=Y,SS=M, 469 437897, AA770561, Hs 146170, hypothetical protein FLJ22969, zf-DHHC,noπe, 469
432886, BE159028 Hs 279704, chromatin accessibility complex 1, none,TM=M„ 469 400843 , , NM_003105* Homo sapiens sortilm related receptor, L(DLR class) A repeats-containing (SORL1), mRNA ,
EGF,fn3,ldl_recept_a Idl recepLb,granulm,BNR,TM=Y,SS=M, 468 433409, AI278802, Hs 25661 , ESTs, pkmase.pkinase, 468 413869, NM.000878, Hε 75596, interieukin 2 receptor, beta none,TM=Y,SS=M, 468
430259, BE550182, Hs 127826, RalGEF-like protein 3, mouse homolog, fn3,RA,RasGEF,TM=M,SS=M, 468 425761, AW664214, Hs 196729, ESTs, SH3,Rιbosomal_S3Ae, 468
431941, AK000106, Hs 272227, Homo sapienε cDNA FLJ20099 fis, clone COL04544, pkmase,Fuπn-lιke,Rxep_L_domam,none, 468 419493 AF001212, Hs 90744, proteasome (prosome, mxropain) 26S subunit, non-ATPase, 11, CDK5_xtιvator,PCI,none, 467 425966, NM 001761, Hε 1973, cyclin F, cyclιn,F-box,cyclιn_C,TM=M„ 467
408056, AA312329, Hs 42331, ephπn-A4, Ephnn,TM=M,SS=M, 467
453476, AI640500, Hε 24633 SAM domain, SH3 domain and nuclear localisation signals, 1, SH3,SAM,SS=M 467 412926, AI879076, Hs 75061, macrophage mynstoylated alanme-πch C kinase substrate, MARCKS,SS=M, 467 424635, AA420687, Hs 115455, Homo sapiens cDNA FLJ14259 fis, clone PLACE1001076, pkiπase.Fuπn lιke,Recep_L_domam,none, 466 446051, BE048061, Hs 37054, ephπn-A3, Ephπn,A_deamιn,dsrm,z-alpha, 466
436729, BE621807, , transmembrane 4 superfamily member 1, none,TM=Y,SS=M, 466 408204, AA454501, Hs 43666, protein tyrosine phosphatase type IVA, member 3, Y_phosphatase,TM=M„ 466 435542, AA687376, , ESTs, SH3,ιg,pkιnase,PH,spectnn,RhoGEF,none, 466
429682, NM_006306, Hε 211602, SMC1 (structural maintenance of chromosomes 1, yeast)-lιke 1, ABC_tran,SMC_N,SMC_C,KID,TM=M„ 466 417497, AW402482, Hs 82212, CD53 antigen, traπsmembrane4,TM=Y,SS=M, 466
418736 T18979, Hs 87908, Snf2-related CBP activator protein, helιcase_C,AT_hook,SNF2_N TM=M„ 465 415117, AF120499, Hs 78016, polynucleotide kmaεe 3'-phosphatase, Vιral_helιcase1,TM=M„ 465 418629, BE247550 Hs 86859, growth fxtor receptor-bound protein 7, SH2,PH,RA,SS=M, 465 426108, AA622037, Hs 166468 programmed cell death 5, DUF122,TM=M„ 464 429263, AA019004, Hs 198396, ATP-bmding cassette, sub-family A (ABC1), member 4, ABC_tran,SRP54,TM=Y,SS=M, 464
431886, L77964, Hs 271980, mitogen-activated protein kiπaεe 6, pkmase,TM=M„ 463 435049, AL122067, Hs 4746, hypothetical protein FLJ21324, none,TM=M„ 463
437763, AA469369, Hs 5831 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor), TIMP,pkιπase,DAG PE bmd.RBD 463 413436, AF238083, Hs 68061, sphmgosine kinase 1 , DAGKc,TM=M„ 463 421846, AA017707, Hs 1432, protein kinase C substrate 80K-H, efhand,ldl_recepLa,SS=M, 462
442590, AI002686, Hs 130313, ESTs, none,Y_phosphatase,Band_41,connexιn, 462 416224, NM.002902, Hs 79088, reticutocalbin 2, EF-hand calcium binding domain, efhand,SS=M, 462 423740, Y07701, Hε 293007, aminopeptidaεe puromycin sensitive, Peptιdase_M1,Armadιllo_εeg, 461 429300, AB011108, Hε 198891, εeπne/threonine-protem kinase PRP4 homolog, pkιnase,TM=M„ 460 447232, AW499834, Hs 327, interleukin 10 rxeptor, alpha, none,TM=M,SS=M, 460
412942, AL120344, Hs 75074, mitogen-xtivated protein kinase-activated protein kinase 2, pkιnase,TM=M„ 460 419596, BE379320, Hε 91448, MKP-1 like protein tyrosine phosphatase, DSPc,, 459
417880, BE241595, Hs 82848, εelxtm L (lymphxyte adhesion molecule 1), EGF.Ixtin c,suεhι,TM=M,SS=M, 459 411125, AA151647, Hε 68877, cytxhrome b-245, alpha polypeptide, none,TM=Y,SS=M, 459 434883, AW381538, Hs 19807, hypothetical protein MGC12959, SH3,PH,WW,RhoGAP,SS=M, 458
447312, AI434345, Hs 36908, xtivatmg transcnption fxtor 1, rrm,zf-RanBP,pkιnase,GST C.Ets.SAM PNT,ABC2_membrane,myosιn head,IQ,Myosιn N.bZIP.zf-
C2H2,PHD,BTB,TFIIS,AT_hook,SAM,TM=M„ 458 435254, AW194689, Hs 30778, ESTs, pkιnase,Bxteπal_PQQ,none, 458
426925, NM.001196, Hs 315689, Homo sapienε cDNA FU22373 fiε, clone HRC06741, Esterase,enolase,Peptιdase_S9,TM=M„ 458 421685, AF189723, Hs 106778, ATPase, Ca transporting, type 2C, member 1, Catιon_ATPase_C,Catιon_ATPaεe_N,E1-E2_ATPase,Hydrolase,XPG_N,TM=Y„ 458
447827, U73727, Hε 19718, protein tyroεine phoεphatase, rxeptor type, U, fn3,ιg,Y_phosphatase,MAM,TM=Y,SS=M, 458
427640, AF058293, Hs 180015, D-dopxhrome tautomerase, COX8,SHMT,MIF,GST C,EF1G_domaιn,GST_N,S1,Fz,Fnzzled,calretιoulm,7tm_2,rrm,PAP assx,TM=Y,SS=M, 457 441085, AW136551, Hs 181245, Homo sapiens cDNA FLJ12532 fis, clone NT2RM4000200, none.none, 457 409581, U66243, Hs 55039, mitogen-xtivated protein kinaεe 12, pkmase,SS=M, 457 423184, NM.004428, Hs 1624, ephπn-A1 , Ephrιn,TM=M,SS=M, 456
443920, AL037764, Hs 35304, Homo sapiens cDNA FU13655 fis, clone PLACE1011503, none,FMO-lιke, 456
422627, BE336857, Hs 118787, transforming growth fxtor, beta-induced, 68kD, Fascιclιn,ABC_tran,ABC_membrane,GTP_EFTU,TM=M,SS=M, 456 418869, AW516565, , gb xq01d05 x1 Soares_NHCeC_cervιcal_tumor Homo sapiens cDNA clone 3' similarto contains Alu repetitive element .contains element MER11 repetitive element „ mRNA sequence, none,RasGAP,WW,IQ, 456 430016, NM_004736, Hs 227656, xenotropio and polytropic retroviruε rxeptor, SPX EXS,TM=Y„ 456
437157, BE048860, Hε 120655, ESTε, IRK.none, 455
422769, AA938905, Hs 120017, olfxtory rxeptor, family 7, subfamily E, member 38 pseudogene, none.none, 455 457918, AL359590, Hs 162604, hypothetical protein DKFZp762M186, PLDc,TM=M„ 455 434467, BE552368, Hs 231853, Homo sapienε cDNA FU13445 fis, clone PLACE1002962, 7tm_1,none, 455 421140, AA298741, Hs 102135, signal sequence rxeptor, delta (translxon-assxiated protein delta), none,TM=Y,SS=M, 455
406364, , , Target Exon, hexapep,TM=M„ 455
434682, AA827165, Hs 191958, immunoglobulin superfamily rxeptor tranεlxation assxiated 2, ig.none, 454 438939, H21012, Hε 287657, Homo εapiens cDNA FU21291 fis, clone COL01963, F5 F8_type_C,pkιπase,Ets,none, 454 433435, BE545277, Hε 340959, Tε translation elongation fxtor, mitxhondπal, EF_TS,UBA„ 454 411165, NM.000169, Hs 69089, galxtosidase, alpha, Melιbιase,SS=M, 454
408956, AK001868, Hε 49344, hypothetical protein FLJ11006, ιon_tranε,TM=Y„ 454
416847, L43821, Hε 80261, enhancer of filamentation 1 (cas-like dxkmg, Crk-assxiated subεtrate related), SH3,TM=M„ 453 410226, AI831958, Hε 61053, hypothetical protein, SH3,TPR,TM=M„ 453 422753, AI928995, Hε 1575, εmall nuclear nbonucleoprotem D3 polypeptide (18kD), Sm,SS=M, 452 418355, L42563, Hε 1165, ATPaεe, H' transporting, nongastπc, alpha polypeptide, E1-E2_ATPase,Catιon_ATPase_C,Catιon_ATPase_N,Hydrolase,TM=Y„ 452
400261, , , Eos Control, ιg,MHC_ll_beta,TM=Y,SS=M, 452 444633, AF111713, Hs 286218, junctional adhesion molxule 1, ιg,TM=Y,SS=M, 452 422940, BE077458, , gb RC1-BT0606-090500-015-b04 BT0606 Homo sapiens cDNA, mRNA sequence, Sec7,PH,ANF_receptor,lιg_chan,WD40,IRK, 452 400303, AA242758, Hs 78136, LIV-1 protein, estrogen regulated, none.none, 451 412604, AW878324 Hε 1804, protein kinase C, iota, pkinase, DAG.PE bιnd,pkιnase_C,OPR,TM=M , 451 448633, AA311426, Hs 21635 tubulin, gamma 1, tubulιn,TM=M„ 4 51
457906, AW975939, Hs 153290, Homosapιenε cDNA FLJ14318 fiε, clone PLACE3000402, none.pkinase 451 5 456362, AW973003 Hs 179909, hypothetical protein FLJ22995, none,TM=M„ 451
429690, AW956329, Hs 23721, ESTs, πone,sugar_tr,Rιboεomal_S25, 450
424618, L29472, Hs 1802 major histxompatibility complex, clasε II, DO beta, ιg,MHC_ll_beta,TM=Y,SS=M, 450 444823, BE262989, Hε 12045, putative protein, Mra1,MBOAT,TM=M,SS=Y, 450
405490, , , NM.031414 Homo sapiens seππe/threonme kinase 31 (STK31), transcnpt vanaπt 1, mRNA , pkιπase,TUDOR,TM=M„ 450 10 424494, U78575, Hs 149255, phosphatidylinoεitol 4-phoεphate 5-kιnase, type I, alpha, PIP5K,SS=M, 450 441031, AI110684, Hs 7645, fibnnogen, B beta polypeptide, fibnnogeπ_C,G-alpha,arf,TM=M SS=M, 450 443951, F13272, Hs 111334, ferπtin, light polypeptide, PMP22_Claudιn,noπe, 450
410423, AW402432, Hs 63489, protein tyrosine phosphatase, non rxeptor type 6, SH2,Y_phosphatase DSPc,TM=M„ 450 429556, AW139399, Hs 98988, ESTs, noπe,TM=M„ 4 50 15 458791, BE615453, Hs 346509, dedicator of cyto-kinesis 1, none,TM=Y„ 449
425209, AL049761, Hs 155140, casein kinase 2, alpha 1 polypeptide, pkinase ABC1,TM=M„ 449
425695, NM.005401, Hs 159238, protein tyrosine phosphatase, non rxeptor type 14, Y_phosphatase,Band_41,DSPc,TM=M , 449 424943, AU077260, Hs 153924, death associated protein kinase 1, ank,pkιπase,death,SPRY,SAP,Rιbosomal_L24e,SRP54,dDENN,DENN uDENN,TM=M„ 449 412970, AB026436, Hs 177534, dual specificity phosphatase 10, Rhodanese,DSPc,SS=M, 448 0 400755, AA635062, , Homo εapieπs mRNA, cDNA DKFZp434O0515 (from clone DKFZp434O0515) zf C3HC4,CARD,BIR,TM=M„ 448 425566 AW162943, Hs 250618, UL16 binding protein 2, ldl_recepLa,PKD,MHC_l,TM=M,SS=Y, 448
410151, X15723, Hs 59242, paired basic amino acid cleaving enzyme (fuπn, membrane assxiated receptor protein), Peptιdase_S8 P,TM=Y,SS=M, 448 423536, L22075, Hs 1666, guanine nucleotide binding protein (G protein), alpha 13, UCR_hιnge,G-alpha,arf,TM=M„ 448 _ _ 424711, NM 005795, Hs 152175, calcitonin receptor-like, 7tm 2,HRM,TM=Y,SS=M, 448
25 427878, C05766, Hs 181022, CGI-07 protein, none,zf-C2H2, 448
443991, NM.002250, Hs 10082, potasεium intermediate/εmall conductance calcium activated channel, subfamily N, member 4, CaMBD,SK_channel,ιon_trans,TM=Y,SS=M, 448 422605, H16646, Hs 118666, hypothetical protem PP591, PAPS_reduct,MoCF_bιosyπth„ 447
410583, AW770280, Hε 36258, ESTε, Moderately similar to JC5238 galactosylceramide like protein, GCP [H sapiens], SH3,PDZ,Guanylate_kιn,πoπe, 447 434419, AL040606, Hs 296938, dual specificity phosphatase 7, DSPc,TM=M„ 447 30 410032, BE065985, , gb RC3 BT0319-120200-014-a09 BT0319 Homo εapienε cDNA, mRNA εequence, abhydrolase_2,none, 446 423078, M35198, Hs 123125, integπn, beta 6, ιntegπn_B EGF,pp-bιndιng,TM=Y,SS=M, 446 400263, , , Eos Control, GTP_EFTU,EFG_C,GTP_EFTU_D2,serpιn,TM=M„ 446 441406, Z45957, Hε 7837, phoεphoprotem regulated by mitogemc pathwayε, pkιnaεe,TM=M„ 445
434551 , BE387162, Hs 280858, ESTs, Highly similar to A35661 DNA excision repair cross-complementing protein ERCC3 [H sapiens], none,TM=M , 445 35 413227, M79082, , ESTs, none.none, 445
441321, H17182, Hs 7771, B-cell asεxiated protein, Band_7,TM=M„ 445
457194, H20669, Hε 35406, ESTε, Highly εimilar to unnamed protein product [H εapienε], noπe,pkιnase,PBD, 445 414745, AA160511, Hs 5326, ammo acid system N transporter 2, porcupine, none.none, 445
404276, , , NM_002944* Homo sapienε v-roε avian UR2 sarcoma vims oncogene homolog 1 (ROS1), mRNA , ffι3,pkιnase,DUF139,TM=Y,SS=M, 445 40 426966, AI493134, , scleroεtm, DAN,TM=M,SS=M, 445
408873, AL046017, Hs 182278, calmodulm 2 (phosphorylase kinase, delta), none.none, 444
426486, BE178285, Hs 170056, Homo εapiens mRNA, cDNA DKFZp586B0220 (from clone DKFZp586B0220), pkinase.none, 444 432798, AA565309, Hs 194015, ESTs, ιntegπn_B,Sema,PSI,TIG,noπe, 444
439668, AI091277, Hs 302634, frizzled (Drosophila) homolog 8, Fnzzled,Fz,7tm_2,toxιn 2,TM=Y,SS=M, 444 45 417886, AA214584, , ESTs, SPRY,7tm_3,ANFjeceptor,none, 443
452098, AI858183, , gb wl46a12 x1 NCLCGAP Ut1 Homo sapienε cDNA clone 3' similar to contains Alu repetitive element,, mRNA εequence, SH3,none, 443 426874, N67325, Hε 347487, ESTε, SH3,TonB boxC.none, 443 422714, AB018335, Hε 119387, KIAA0792 gene product, DUF221,TM=Y,SS=M, 442 410741, Z11695, Hε 324473, mitogen-xtivated protein kinase 1, pkinaεe.noπe, 442 50 432193, AA372264, Hε 273193, hypothetical protein FU10706, pkιnase,TM=M„ 441 409506, NM.006153, Hε 54589, NCK adaptor protein 1, SH2,SH3,TM=M„ 441 429390, AB040942, Hs 201500, KIAA1509 protein, none,TM=M„ 441 421859, AA356620, Hs 108947, KIAA0050 gene product, ank,PH,ArfGap,SS=M, 441 451527, AF022813, Hs 26518, transmembrane 4 superfamily member 7, none.none, 441 55 421748, NM_014718, Hs 107809, KIAA0726 gene product, cadheππ,TM=Y„ 440
410416, BE410072, Hs 63304, protein phosphataεe methylesterase-1, none,TM=M„ 440 450457, AA367701, Hs 6639, KIAA1624 protein. none,TM=M,SS=M, 440 433029, NM.014322, Hs 279926, opsin 3 (encephalopsin), 7tm_1,Monooxygenase,TM=Y,SS=M, 440 408805, H69912, Hs 48269, vxcinia related kinase 1, pkιnase,TM=M„ 440 60 421585, U95626, Hs 302043, chemokine (C-C motif) receptor-like 2, 7tm_1,TM=Y,SS=M, 440
440014, AW960782, Hs 6856, ash2 (abεent, εmall, or homeotic, Drosophila, homolog) like, SPRY,BAG,UPF0001, 440 451154, AA015879, Hs 33536, ESTs, TIMP.none, 440
433895, A1287912, Hs 3628, mitogen-xtivated protein kmase kinase kinase kinase 4, pkmase,zf-C4,CNH,ERM,TM=M„ 440 422034, AC006486, Hs 333069, Ets2 repreεsor fxtor; Ets,TM=M„ 439 65 444009, AI380792, Hε 135104, ESTε, TNFR_c6,TIL,πone, 439
420020, BE295866, Hε 94382, adenoεme kinaεe, pfkB,SS=M, 439
416207, NM.014745, Hs 79077, Homo sapiens, clone MGC 2908, mRNA, complete eds, noπe,TM=Y,SS=M, 439 417655, AA780791, Hs 14014, hypothetical protein FU14813, pkιnase,pkιnase_C,TM=M„ 439 402915, , , ENSP00000202587* Bicarbonate transporter-related protein BTR1 , HC03_cotransp,TM=Y„ 439 70 453199, AI336266, Hε 32353, mitogen-xtivated protein kinaεe kinase kinase 4, pkιnase,TM=M„ 438 416033, NM 012201, Hs 78979, Golgi apparatus protein 1, cys_nch_FGFR,TM=Y,SS=M, 438 453672, U73531, Hs 34526, G protein-coupled rxeptor, 7tm 1,TM=Y,SS=M, 438 437852, BE001836, Hs 256897, ESTs, Weakly similar to dJ365012 1 [H sapiens], GPS,7tm_2,TM=Y„ 438 420039, NM_004605, Hs 94581 , sulfotranεferaεe family, cytosolic, 2B, member 1 , Sulfotransfer,SS=M, 438 75 412834, R77123, Hs 79881, Homo sapieπε cDNA FLJ23006fiε, clone LNG00414, 7tm_1,none, 438
452203, X57522, , transporter 1, ATP-bmding cassette, sub-family B (MDR/TAP), ABC tran,ABC_membraπe,SRP54,Thymιdylate_kιn,TM=Y,SS=M, 437 425317, AW205118, Hs 210546, interleukin 21 rxeptor, none,TM=Y,SS=M, 437 432945, AL043683, Hε 8173, hypothetical protein FLJ 10803, none,TM=M,SS=M, 437 _ . 424028, AF055084, Hs 153692, Homo sapiens cDNA FLJ14354 fis, clone Y79AA1001384, highly similarto Homo εapienε very large G-protein coupled receptor-1 (VLGR1) mRNA,
80 none.none, 437
434071, AF116653, Hε 34192, Homo εapienε PRO0823 mRNA, complete eds, noπe,TM=M„ 437
412596, AA161219, Hs 799, diphtheria toxin receptor (hepann binding epidermal growth factor-like growth factor), EGF,TM=Y,SS=M, 4 36
440270, NM_015986, Hs 7120 cytokine receptor-like molxule 9, fn3,SS=M, 436 432887, AI864771, Hs 27954 CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), none,TM=Y,SS=M, 436 436943, AA773838, Hs 5353, caspase 10, apoptosis related cysteine protease, ICE_p10,ICE_p20,DED,TM=M„ 436 457897, AI356125, Hs 345168, ESTs Weakly similar to HXA2_HUMAN HOMEOBOX PROTEIN HOX A2 [H sapiens], homeobox.NA.NA, 436 406671, AA129547, Hs 285754, met proto oncogene (hepatocyte growth factor rxeptor), Sema,pkιnase,TIG,PSI,none, 436 413969, X14034, Hs 75648, phospholipaεe C, gamma 2 (phosphatidylmoεitol-spxific) SH2,SH3,C2,PH,PI-PLC-Y,PI-PLC-X,PDGF,SS=M, 435
408101, AW968504, Hs 123073, CDC2-related protein kinase 7, none.none, 435
414029, BE297731 Hs 75709, manπose 6-phosphate rxeptor (cation dependent), Man 6-P_recep TM=M,SS=M, 435 425069, AA687465, Hs 298184, potasεium voltage-gated channel, shaker-related subfamily, beta member 2, aldo.keLred.none, 435 438937, AW952654 Hs 244624, ESTs, EPH.Ibd pkmase,fn3,SAM,πone, 435 412584, X54870, Hs 74085, DNA εegmeπt on chromosome 12 (unique) 2489 expressed sequence none,lxtιπ_c, 435
436540, BE397032 Hs 14468, hypothetical protein MGC14226, rrm,7tm_1,SNF,TM=M„ 434 435267, N23797, Hs 110114, ESTs, none,Syja_N Exo_endo_phos, 434 405616, , , Target Exon, πoπe,SH3 BAR, 434
432141, BE410964, Hs 272736, nuclear receptor binding protein, pkιnase,TM=M„ 433 417927, R73095, Hs 24122, ESTs, none.pkinase, 433
429849, U33053, Hs 2499, protein kmase C-like 1, pkιnase,pkιnase_C,HR1,TM=M„ 433 425743, BE396495 Hs 159428, BCL2-asεocιated X protein, Bcl-2,TM=Y„ 433 453863, X02544, Hε 572, oroεomucoid 1, lιpxalιn,aldedh,ubιquιtm,IRK,SS=M, 433
400847, , , NM_003105* Homo εapienε εortilin related receptor, L(DLR class) A repeats-containing (SORL1), mRNA , EGF,fn3,ldl recepLa ldl_rxepLb,granulιn,BNR,TM=Y,SS=M, 433
414914, U49844, Hs 77613, ataxia telaπgixtasia and Rad3 related, FAT,FATC,PI3_PI4_kιnase,TM=M„ 433 413858, NM.001610 Hs 75589, xid phosphatase 2, lysoεomal, xιd_phosphat,TM=Y,SS=M, 433
442539, AL119506, Hs 58220, Homo sapiens cDNA FLJ23005 fis, clone LNG00396, highly similar to AF055023 Homo sapienε clone 24723 mRNA εequence, RasGAP.adenylatekmase, 433 419607, R52557, Hs 91579, Homo sapiens clone 23783 mRNA sequence, IMP4,TM=M„ 432
436703, AW880614, Hs 146381, RNA binding motif protein, Xchromosome, rrm,SH3,PH,CH,RhoGEF, 432 414899, AW975433, Hs 36288, ESTs, pkιnase,SH2,SH3,none, 432
444895, AI674383, Hε 22891 , solute earner family 7 (cationic ammo xid transporter, y syεtem), member 8, ASC,death,TNFR_c6, 431 415135, AW673559, Hε 78040, KDEL (Lyε-Aεp Glu-Leu) endoplasmic reticulum protein retention rxeptor 1, ER_lumen_recept none, 431 444070, NM_015367, Hs 10267, MIL1 protein, Bcl-2,TM=Y„ 431
422611, AA158177, Hs 118722 fucosyltransferase 8 (alpha (1 ,6) fucosyitransferase), SH3,K-box TM=M,SS=Y, 431 437162, AW005505, Hs 5464, thyroid hormone receptor coactivat g protein, bromodomaιn,TM=M„ 430 440983, M20681 , Hs 7594, εolute earner family 2 (facilitated glucose transporter), member 3, sugar_tπTM=Y,SS=M, 430 414080, AA135257, Hε 47783, B aggressive lymphoma gene, A1pp,TM=M , 430 415072, BE253687, Hs 77876, Homo sapiens, clone IMAGE 3461982, mRNA, partial eds Metallophos,Armadιllo_seg,TM=M , 430
442994, AI026718 Hs 16954, ESTs, ank,pkιnase,death,Rιboεomal_S14, 430
432328, AI572739, Hε 195471, 6 phosphofructo-2-kιnase/fructose-2,6 biphosphataεe 3, PGAM,6PF2K,TM=M„ 429 439490, AW249197, Hs 100043, ESTs, Weakly simitar to A46302 PTB-ass∞iated splicing fxtor, long form [H sapiens], none,TM=M„ 429 422005, BE266556, Hs 110702, Homo sapiens mRNA, cDNA DKFZp761E212 (from clone DKFZp761E212), noπe,Na_H_Exchangeπ 429 415214, AI445236 Hs 125124, EphB2, fn3,pkιnase,SAM,EPH_lbd,TM=Y,SS=M, 429
430316, NM.000875 Hs 239176, insulin like growth fxtor 1 receptor, fn3,Fuπn like pkιnase,Recep_L_domaιn,TM=M,SS=M, 4 29 429099, BE439952, Hs 196177, phosphorylase kinase, gamma 2 (testis), pkιnase,Bx_DNA_bιndιng,TM=M„ 429 425843, BE313280, Hs 159627, death assxiated protein 3, myb DNA-bmdιng,PAH,BAH,bromodomaιn,PHD,SET,TM=M„ 428 437603, AW979259, Hs 293673, ESTs, death.none, 428 439975, AW328081 , Hs 6817, inosine tπphosphataεe (nucleoεide tπphosphate pyrophosphatase), Ham1 p_lιke,TM=M„ 428
424512, X53002, Hε 149846, integπn, beta 5, integnn B,EGF,TM=Y,SS=M, 428 442980, AA857025, Hε 8878, kineεiπ-like 1, kιneειn,Luteo_ORF3,DUF164,TM=M„ 428
420166, AW732276, Hε 95583, tranεmembrane 4 superfamily member (tetraspaπ NET-7), transmembrane4,TM=Y,SS=M, 427 409582, R27430, Hs 271565, ESTs, none.Neur chan LBD.Neur.chan.memb, 427 439096, AA830185, , ESTs, ras.none, 427
414561, AI064813, Hs 195155, Homo sapiens ammo xid transport syεtem N2 (SN2) mRNA, complete cdε, Aa_trans,TM=Y„ 427 411835, U29343, Hs 72550, hyaluronan mediated motility rxeptor (RHAMM), bZIP,SS=M, 4 27 428781, AF164799, Hs 193384, putatative 28 kDa protein, pkιnase,DAG_PE-bιnd,pkιnase_C,OPR,SS=M, 427 430603, AA148164, Hs 247280, HBV assxiated fxtoπ zf-C3HC4,zf-RanBP,pkιnase, 427 415149, X12451, Hs 78056, cathepsin L, Peptidase C1,SS=M, 426
444838, AV651680, Hs 208558, ESTs, ιntegπn_A,FG-GAP,noπe, 426 402328, , , Target Exon, pkιnase,TM=M„ 426
416094, AW995512, Hs 225977, nuclear rxeptor coxtivator 3, none.none, 426 420942, H03514, Hs 15589, ESTs, none.pkinase, 426 453902, BE502341 , Hs 3402, ESTs, none.none, 426
425505, AL036458, , gb DKFZp564D2062_r1 564 (εynonym hfbr2) Homo εapienε cDNA clone DKFZp564D20625', mRNA εequence, arf,G-alpha,none, 426 427344, NM_000869, Hε 2142, 5-hydroxytryptamine (serotonin) rxeptor 3A, Neur_chan_LBD,Neur_chan_memb,TM=Y,SS=M, 426 432269, NMJJ02447, Hs 2942, mxrophage stimulating 1 rxeptor (c-met-related tyrosine kinase), pkιnase,Sema,PSI,TIG,A4_EXTRA,TM=M,SS=M, 426 417007, AF224741, Hs 80768, chlonde channel 7, CBS.voltage CLC,TM=Y„ 426 447860, AW954377, Hs 26412, nng finger protein 26, zf-C3HC4,TM=Y,SS=M, 426
442300, AI765908, Hs 129166, ESTs, none,SS=M, 425
421856, NM_016447, Hs 108931, MAGUK protein p55T, Protein Assxiated with Lms 2, SH3,PDZ,Guanylate_kιn,L27,TM=M„ 425 452110, T47667, Hs 28005, Homo sapiens cDNA FLJ11309 fis, clone PLACE1010076, pkιnase,Actιvιπ_recp,noπe, 425
422451 , AA310753, Hε 42491 , ESTε, Weakly similar to S65657 alpha-1 C-adrenergic rxeptor splice form 2 [H sapienε], PDZ,SH2,STAT,STAT_bmd,STAT_prot,none, 425 453955, AW579207, Hε 304666, ESTε, Weakly similar to I78885 senne/threonine-εpxific protein kinase [H εapienε], fn3,ιg,MAM,none, 425
457670, AF119666, Hε 23449, insulin rxeptor tyrosine kinase εubstrate, SH3,TM=M„ 425
419133, U46116, Hs 89627, protein tyrosine phosphatase, rxeptor type, G, fn3,Y_phosphatase,carb_anhydrase,DSPc,TM=Y,SS=M, 425 419660, BE280337, Hs 194693, solute earner family 7 (cationic ammo xid transporter, y system), member 7, aa_permeases,TM=Y,SS=M, 425 415198, AW009480, Hs 943, natural killer cell transcπpt4, none,TM=M„ 424 416440, AI823912, Hs 79335, Homo sapiens, Similarto SWI/SNF related, matnx asεxiated, xtin dependent regulator of chromatin, subfamily d, member 1, clone MGC 15280 mRNA, complete eds, SWIB,TM=M„ 4 24 419169, AW851980, Hs 262346, ESTs, Weakly similarto S72482 hypothetical protein [H sapiens], none,εpxtπn,SH3,PH,CH, 424 449444, AW818436, Hs 23590, solute earner family 16 (monocarboxylic xid transporterε), member 4, none,TM=Y,SS=M, 424 433848, AF095719, Hε 93764, carboxypeptidaεe A4, Zn_carbOpept,Propep_M14,SS=M, 424 442213, N36110, Hε 305971, solute camerfamily 2 (facilitated glucoεe transporter), member 10, sugar_tr,TM=Y,SS=M, 424
412681, AW983655, Hs 172004, Win, fn3,ιg,SGXXSG,pkιnase,TM=M„ 424
424653, AW977534, Hs 151469, calciumfcalmodulin dependent seπne protein kinase (MAGUK family), none.none, 424 421066, AU076725, Hs 101408, branched chain aminotransferase 2, mitxhondπal, amιnotran_4„ 423
Figure imgf000575_0001
417903, NM.002342, Hs 1116, lymphotoxin beta receptor (TNFR superfamily, member 3), TNFR_c6,TM=M SS=M, 4 14
428307, W27393, Hs 183648, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (lipππ), alpha 1, SAM,SH3,HS1_rep, 4 14 442434, AA995787, Hs 129583 ESTs, IRK.noπe, 4 13
438361, AA805666, Hs 146217, Homo sapienε cDNA FLJ23077 fiε, clone LNG05840 pkιnase,pkιnase_C,none, 4 13 445580, AF167572, Hs 12912, skbl (S pombe) homolog, πone,SS=M, 4 13
421425, AK001564, Hs 104222, hypothetical protein FU10702, efhand,kazal,arf,ras,7tm_1,TM=M„ 4 13
400252, , , NM.004651* Homo εapiens ubiquitin spxific protease 11 (USP11), mRNA substrate 1 (PTPNS1), mRNA , UCH-1 ,UCH-2,TM=M„ 4 13
446641, AL049229, Hs 15787, Homo sapiens mRNA, cDNA DKFZp564O1016 (from clone DKFZp564O1016), πone.pkmase.PBD, 4 13 400209, , , NM.001666 Homo sapiens Rho GTPase activating protein 4 (ARHGAP4), mRNA VERSION NM_0060832 Gl, FCH,RhoGAP,SH3,TM=M„ 4 13 429012 AW629596, Hs 194726, BCL2-ass∞ιated athanogene 4, Sm,BAG,SS=M, 4 13 411826, AW947946, Hs 26706, CGI-121 protein, none.DSPc, 4 13 423189, M59371, Hs 171596, EphA2, fn3,pkιnase,SAM,EPH_lbd,TM=Y,SS=M 4 12 413934, U03056, Hs 75619, hyaluronoglucosamimdase 1, ιntegπn_B,Glyco_hydro_56,SS=M, 4 12 414874, D26351, Hε 77515, mositol 1,4,5-tπphosphate rxeptor, type 3, ιon_trans,MIR,RYDR_ITPR,TM=Y„ 4 12 432047, NM_016247, Hs 272380, interphotoreceptor matnx proteoglycan 200, EGF.SEA TM=Y,SS=M, 4 12
451820, AW058357, Hs 199248, ESTs, 7tm 1,TM=Y,SS=M, 412
445515, BE388665, Hε 179999, Homo εapienε, clone IMAGE 3457003, mRNA, zf-C2H2,BTB,K_tetra,WD40,Syntaxιn, 4 12 424539, L02911, Hε 150402, Activin A receptor, type I (ACVR1) (ALK-2), pkιnase,Actιvιn_recp,TM=M,SS=M, 4 12 405110, , , C7000199 gι|12643960|sp|Q9Y6T7|KDGB_HUMAN DIACYLGLYCEROL KINASE, BETA (DIGLYCERIDE KINASE , none.none, 412 441026, AW179058 Hs 99858, πbosomal protein L7a, pkιnase,LRR,LRRCT,Rιbosomal_L7Ae,none, 411
443142 AI696513, Hs 108705, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform, HEAT,Vιtellogenιn_N,HEAT_PBS,SS=M, 4 11 450505, NM 004572, Hs 25051 , plakophilin 2, Armadιllo_εeg,TM=M„ 4 11
459601, AL044470, Hε 270604, ESTε, Weakly simitar to ALU7.HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY [H sapienε] none,SH3,PGAM,UBA, 4 10 417300, AI765227, Hs 55610, solute earner family 30 (zinc transporter), member 1, Catιon_eff!ux,TM=Y,SS=M, 4 10
427315, AA179949, Hs 175563 Homo sapienε mRNA, cDNA DKFZp564N0763 (from clone DKFZp564N0763), none,εpxtπn,SH3,PH,CH, 4 10 416239, AL038450, Hε 48948, ESTs, E1-E2_ATPase,Catιoπ_ATPaεe_C,Catιon_ATPaεe_N,Hydrolaεe,none, 4 10 429311, AF080157, Hs 198998, conserved helix-lxp-helix ubiquitous kinase, pkinase.none, 4 10
412146, M92444, Hs 73722, APEX nuclease (multifunctional DNA repair enzyme), Exo_endo_phoε,Atrophιπ-1,BNR,Kelch,TM=M„ 4 10 418420, AW604405, Hs 324874, hypothetical protein MGC3079, Phosphodιest,TM=Y„ 4 10
434396, AA632270, Hs 162851, Homo sapiens cDNA FLJ14317 fiε, clone PLACE3000401 , pkmaεe.none, 4 10 454438 AA224053, Hε 172405, cell diviεion cycle 27, SPRY,7tm_3,ANF_receptor, 4 10 439578, AW263124, Hs 315111 , nuclear receptor co-repressor/HDAC3 complex subunit, WD40,TM=M„ 4 10
451995, AI827431, Hs 224645, ESTs, Weakly similarto IF16_HUMAN GAMMA-INTERFERON INDUCIBLE PROTEIN 1FI-16 [H sapienε], none,PAAD_DAPIN,HIN, 4 10 420340, NM 000734, Hs 97087, CD3Z antigen, zeta polypeptide (TιT3 complex), ITAM,TM=M,SS=M, 4 10
442942, AW167087, Hs 131562, ESTs, pkinase.none, 409 428187, AI687303, Hs 285529, G protein-coupled receptor 49, 7tm_1,none, 409
418838, AW385224, Hs 35198, xtonudeotide pyrophosphatase/phosphodieεteraεe 5 (putative function), Phosphodιest,TM=Y,SS=M, 409 416445, AL043004, Hs 79337, KIAA0135 protein, pkιnase,PAS,TM=M„ 408 427001, NM 006482, Hs 173135, dual spxificity tyrosιne-(Y) phosphorylation regulated kinase 2, pkιnase,TM=M„ 408
403608, , , C3001199 gι]7494834|pιr||T15308 hypothetical protein B02862 - Caenorhabditis elegans||41, 7tm_1,7tm.2,GPS,WIF,TM=Y,SS=M, 408 427177, AB006537, Hs 173880, interleukin 1 receptor xcessory protein, ιg,TIR,TM=Y,SS=M, 408
401241, AB028989, , mitogen-xtivated protein kmase 8 interacting protein 3, Cys_knot,TGF-beta,vwa,vwc,vwd,TIL,DUF139,SS=M, 407 444805, AB007899, Hs 12017, homolog of yeast ubiquitin-protem ligase Rsp5, potential epithelial sodium channel regulator, WW,HECT,RNA_pol_A,none, 407 448888, AW196663, Hs 200242, caspase rxruitmeπt domain protein 6, CARD,TM=M„ 406
426006, R49031, Hs 22627, ESTs, pkmase.TBC, 406
434521, NM.002267, Hs 3886, karyophenn alpha 3 (importin alpha 4), Armadιllo_seg,IBB,TM=M„ 406 408761, AA057264, Hs 238936, ESTs, Weakly similar to (defline not available 7496841) [C elegans], 7tm_1,none, 405 425289, AW139342, Hs 155530, interferon, gamma-inducible protein 16, PAAD_DAPIN,HIN,SS=M, 405 413109, AW389845, Hs 110855, ESTs, PH04,none, 405
426457, AW894667, Hε 169965, chimeπn (chimaeπn) 1, DAG PE-bιnd,RhoGAP,SH2,TM=M„ 405 435730, AB020635, Hs 4984, KIAA0828 protein, AdoHcyase,TrkA-N,2-Hxιd_DH_C,TM=M„ 404
429747, M87507, Hε 2490, caspase 1, apoptosis related cyεteine protease (interleukin 1, beta, convertase), CARD,ICE_p10,ICE_p20,SS=M, 404 444378, R41339, Hε 12569, ESTε, ιg,pkιnase,LRR,LRRNT,LRRCT,none, 404 449843, R85337, Hs 24030, solute earner family 31 (copper transporters), member 2, none,TM=Y,SS=M, 404 427359, AW020782, Hs 79881, Homo sapiens cDNA FLJ23006 fis, clone LNG00414, 7tm_1,none, 404 413095, AA494359, Hs 30715, potasεium voltage-gated channel, Isk-related family, member 3, none.START, 404
418540, AI821597, Hs 90877, ESTs, Weakly similarto ALU1 HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H εapienε], ank.CAP GLY,7tm 1, 403 442007, AA301116, Hs 142838, nuclxlar phosphoprotein Nopp34, rrm,IRK,SS=M, 402
448659, AF191838, Hε 21712, TANK-bmding kinaεe 1, pkιnase,TM=M„ 402 412935, BE267045, Hs 75064, tubulin-specific chaperone c, none,, 402 414844, AA296874, Hs 77494, deoxyguanosine kmase, dNK„ 402 445817, NM.003642, Hs 13340, histone xetyltransferaεe 1, none,TM=M„ 402 426728, NM_007118, Hε 171957, tπple functional domain (PTPRF interacting), SH3,ιg,pkmaεe,PH,εpxtπn,RhoGEF,TM=M„ 402
420676, AI434780, Hε 4248, vav 2 oncogene, RhoGEF,PH,CH,SH2,SH3,DAG_PE-bιnd,πone, 402
405102, , , C15001220* gι|4469558|gb|AAD21311 1| (AF126008) breast cancer nuclear rxeptor-bindmg auxi, DAG_PE-bιnd,PH,RhoGEF,DC1,SS=M, 402 439964, AI732902, Hs 124652, Homo sapiens cDNA FLJ12376 fis, clone MAMMA1002494, pkinase.none, 401 429680, AL035754, Hs 2474, toll-like rxeptor 1 , LRR,LRRCT,TIR,TM=M,SS=M, 401 453891 , AB037751 , Hs 36353, Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 1035904, none.none, 401
426535, AU077012, Hs 288582 ESTs, Weakly similarto ubiquitous TPR motif, Y isoform [H sapiens], Kunιtz_BPTI,Kunιtz_BPTI,7tm_2,HRM, 399 424232, AB015982, Hs 143460, protein kinase C, nu, pkιnase,DAG_PE-bιnd,PH,TM=M„ 399 408308, AL033377, Hε 44197, hypothetical protein DKFZp564D0462, none none, 398 449517, AW500106, Hs 23643, seπne/threonme protein kinase MASK, pkιnase,TM=M„ 398 404185, , , Target Exon, sugar_tπTM=Y,SS=M, 398
441226, BE563042, Hs 118820, Homo sapiens, Similar to RIKEN cDNA 0610012G03 gene, clone MGC 14132, mRNA, complete eds, none,TM=M„ 398 429638, AI916662, Hs 211577, kinectin 1 (kines rxeptor), bZIP,Tropomyosm,spectπn,LBP_BPI CETP,B56,M,TM=Y,SS=M, 397 417386, AL037228, Hs 82043, D123 gene product, NUDIX,sxY,E1_dehydrog transket_pyr,TM=Y,SS=M, 397 452721, AJ269529, Hs 301871, solute camerfamily 37 (glycerol-3-phosphate transporter), member 1, MORN,sugar_tr;TM=Y,SS=M, 396 417183, R52089, Hs 172717, ESTs, pkιnase,LRRCT,ιg,LRR,LRRNT,noπe, 395
439176, AI446444, Hs 190394, ESTs, Weakly similar to B28096 lιne-1 protein ORF2 [H sapiens] none,TM=M„ 394
424490, AJ278016, Hs 55565, aπkyπn repeat domain 3, aπk,pkιnase,TM=M„ 394
422610, AF153820, Hε 1547, potassium inwardly-rectifying channel, subfamily J, member 2, IRKTM=Y„ 394 450746, D82673, Hs 278589 general transcnption factor II, i, none,SH3,PX, 394
418516, NM_006218, Hs 85701, phosphoιnosιtιde-3-kιnase, catalytic, alpha polypeptide, PI3_PI4_kιnase,PI3Ka,PI3K_C2,PI3K_rbd,PI3K_p85B,none, 394 414217, AI309298, Hε 279898, Homo sapiens cDNA FLJ23165 fis, clone LNG09846, none.NA.NA, 393 416537, T99086, Hs 144904, nuclear rxeptor co-repressor 1, myb_DNA-bιndιng,RNA_pol_A,noπe, 393 450747, AI064821, Hs 318535 ESTs Highly similar to 1818357A EWS gene [H sapiens] nm zf RanBP,GAS2 393
444825, AW167613, , mitogen-xtivated protein kinase kinase kmase 8, pkιnase,TM=M„ 393 408354, AI382803, Hs 159235, ESTs, none.none, 393
453945, NM 005171, Hs 36908 xtivatmg transcnption factor 1, rrm.zf-RanBP pkιnase,GST_C,Ets,SAM_PNT,ABC2_membrane,myoειn_head,IQ Myosιn_N,bZIP,zf- C2H2,PHD,BTB,TFIIS,AT_hook,SAM,TM=M„ 393 428532, AF157326, Hs 184786, TBP-interactmg protein, Armadιllo_seg,VHS,HEAT,TM=M„ 392
413967, AW204431, Hs 117853, ESTs, Weakly similarto I38022 hypothetical protein [H εapieπs], Armadιllo_seg,IBB,PHD,DDT,none 391 415906, AI751357, Hs 288741, Homo sapiens cDNA FLJ22256 fis, clone HRC02860, Ephπn.none, 391 450139, AK001838, Hs 296323, serum/glucxorticoid regulated kinase, none.none, 391 440255, A1932285, Hs 160569, ESTs, none.pkinase, 390 421077, AK000061, Hs 101590, hypothetical protein, ank pkιnase,death,SPRY,SAP,Rιbosomal_L24e,SRP54,dDENN,DENN,uDENN,TM=M„ 390
433211, H11850, Hs 12808, MARK, pkιnase,UBA,KA1,SS=M, 390 433233, AB040927, Hs 301804, KIAA1494 protein, SH3,zf-C3HC4,TM=M„ 390
419609, U46415, Hs 270379, gb HSU46415 Human pancreatic cancer cell line Patu 8988t Homo sapienε cDNA clone xs476, mRNA sequence, PWWP.none, 390 433198, AA992841, Hs 27263, KIAA1458 protein, none.none, 389 407721, Y12735, Hs 38018, dual spxificity tyrosine (Y)-phosphorylatιon regulated kinase 3, pkιnase,TM=M„ 389
427657, AV652249, Hs 180107, polymerase (DNA directed), beta, none,TM=M , 389 453035, AW581943, Hs 334, Rho guanine nuclxtide exchange factor (GEF) 5, none.none, 389
446329, NMJ13272, Hs 14805, solute earner family 21 (organic aπion transporter), member 11, kazal,OATP_N,OATP_C,TM=Y,SS=M, 389 429922, Z97630, Hs 226117, H1 histone family, member 0, lιnker_hιstone,TM=M„ 388 432074, AA525248, Hs 149723, ESTε, Y_phoεphatase,none, 388
435143, R12375, Hs 194600 ESTs, SH3,ιg,pkιnase,PH,spectπn,RhoGEF,πoπe, 3 87 423198, M81933, Hs 1634, cell division cycle 25A, Rhodanese.noπe, 387 428474, AB023182, Hs 184523, KIAA0965 protein, pkιnase,TM=M„ 387
419073, AW372170, Hs 183918, Homo sapienε cDNA FLJ12797 fis, clone NT2RP2002066, highly similarto Rartus norvegicuε tranεmembrane rxeptor Unc5H2 mRNA death ZU5,SS=M, 386
415457, AW081710, Hε 7369, ESTε Weakly similar to ALU1 HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens]
MORN,sugar_tr,TM=Y,SS=M, 386 447061, D86964, Hs 17211, dedicator of cyto-kinesis 2, SH3,TM=M„ 386 426490, NM.001621, Hs 170087, aryl hydrocarbon receptor, PAC,PAS,TM=M„ 386 451961, NM.003800, Hs 27345, RNA guanylyltransferase and 5'-phosphatase, mRNA_cap_enzyme,DSPc,DNA_lιgase,mRNA_cap_C,TM=M„ 386
417874, BE616160, Hs 82829, protein tyrosine phosphatase, non-rxeptor type 2, Y_phosphatase,TM=Y„ 3 86 446874, AW968304, Hε 56156, ESTε, noπe.RGS, 385
418630, AI351311, Hs 251946, poly(A)-bιndιng protein, cytoplasmic 1-lιke, pkinase.none, 385 416140, AI918035, Hs 301198, roundabout (axon guidance rxeptor, Drosophila) homolog 1, none.none, 385 425474, Z48054, Hs 158084, peroxisome rxeptor 1, TPR,TM=M„ 385
413073, AL038165, Hs 75187, traπslxase of outer mitxhoπdπal membrane 20 (yeast) homolog, MAS20,zf-A20,VPS9,TM=M,SS=M, 385 411770, NM 014278, Hε 71992, heatεhxk protein (hεp110 family), HSP70,TM=M„ 384 428782, X12830, Hs 193400, interleukin 6 rxeptor, fn3,ιg,TM=Y,SS=M, 384 450684, AA872605, Hs 25333, interleukin 1 rxeptor, type II, ιg,TM=Y,SS=M, 384 433376, AI249361, Hs 74122, caspase 4, apoptosis-related cysteine protease, CARD,ICE_p10,ICE_p20,SS=M, 383
440332, AI218517, Hs 188051, ESTs, fn3,pkmase,SAM,EPH_lbd,none, 383 445803, AV655264, Hs 4283, ESTε, pkιnaεe,RGS,PH,myosm_head,Myosιn_taιl, 383 435905, AW997484, Hs 5003, KIAA0456 protein, SH3,RhoGAP,FCH,TM=M„ 383
414991, C17898, , gb C17898 Human placenta cDNA (TFujiwara) Homo sapiens cDNA clone GEN-554E105', mRNA sequence, Zip.none, 383 423067, AA321355, Hs 285401, colony stimulating fxtor 2 rxeptor, beta, low-affinity (granulxyte- xrophage), fn3,TM=Y,SS=M, 382
419088, AI538323, Hs 52620, integπn, beta 8, ιntegπn_B,none, 382 411704, AI499220, Hs 71573, hypothetical protein FLJ10074, pkιnase,TM=M„ 382 459346, AW510557, Hs 258016, EST, none,TM=M„ 382 445330, R52656, Hs 21691 , ESTs, 7tm_1.none, 382 451452, BE560065, Hε 26433, dolichyl phosphate (UDP-N xetylglueosamme) N-xetylglucosamiπephosphotransferaεe 1 (GlcNAc-1-P tranεferase), Glycos_transf_4,TM=Y,SS=M,
381 405545, , , Target Exon, ABC_traπ,SRP54,ABC_membraπe,TM=Y,SS=M, 381 ,
448165, NMJM5591, Hs 20555, meiotic recombination (S cerevisiae) 11 homolog B, Metallophos,Rιbosomal_L15e,SS=M, 381 416305, AU076628, Hs 79187, coxεackie virus and adenovirus rxeptor; ιg,TM=Y,SS=M, 380 415444, BE247295, Hs 78452, solute earner family 20 (phosphate transporter), member 1, PH04,LIM,TM=M„ 380
421684, BE281591, Hs 106768, hypothetical protein FLJ10511, Armadιllo_seg,SS=M, 380
438581 , AW977766, Hε 292133, ESTε, Moderately similar to 178885 seπne/threonine-εpxifio protein kinaεe [H εapiens] pkιnase,RI01 ,none, 379 439199, R40373, Hs 26299, ESTs, lonjrans.none, 378
450931, N25156, Hε 25648, tumor nxrosis fxtor rxeptor superfamily, member 5, TNFR_c6,TM=Y,SS=M, 378 417691, AU076610, Hs 82399, low density lipoprotein rxeptor defxt C complementing, none,SS=M, 378
430355, NM.006219, Hs 239818, phosphoιnosιtιde-3-kιnaεe, catalytic, beta polypeptide, PI3_PI4_kιnase,PI3Ka,PI3K_C2,PI3K_rbd,PI3K_p85B,TM=M„ 378 448119, H38587, Hs 346509, dedicator of cyto-kinesis 1, none,TM=Y„ 378
442013, AA506476, Hs 10600, Human DNA sequence from clone RP11-353C18 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands Contains the NIFS gene for cysteine desulfuraεe, two geneε for novel protemε and the gene for the splicing fxtor CC1 3 with a sxond isoform (CC1 , none.none, 377 425481, AW978162, Hs 18571, ESTs, noπe,Oxysterol_BP, 377
411411 , AA345241, Hs 55950, ESTε, Weakly similar to KIAA1330 protein [H sapiens], RNA_pol_A,ιg,MHCK_EF2_kιnase,SS=M, 377 426866, U02330, Hs 172816, πeuregulin 1, Peptιdase_M49,EGF,ιg,Neuregulιn,TM-M„ 377 430396, D49742, Hs 241363, hyaluronan-bindmg protein 2, ank,death,ZU5,EGF,kπngle,trypsιπ,Nebulm,UM,SS=M, 377 434398, AA121098 Hs 3838 serum inducible kinase, pkιnase,POLO_box,TM=M„ 377 415485, AW272990, Hs 18571, ESTs, none,Oxysterol_BP, 376
453226, AA641926, Hs 61712, pyruvate dehydrogenase kinase, isoenzyme 1, HATPase.c.none, 376 418758, AW959311, Hs 172012, hypothetical protein DKFZp434J037, pkinase RI01,TM=M„ 376
424842, AA034127, Hs 153487, signal transducing adaptor molxule (SH3 domain and ITAM motif) 1, SH3,VHS,UIM,TM=M„ 375 426500, NM.014638, Hs 170156, KIAA0450 gene product, C2,PI-PLC-Y,TM=M„ 375 419952, AK000967, Hs 93872, KIAA1682 protein, noπe,TM=M„ 375
425424, NMJ04954, Hs 157199, ELKL motif kinase, pkinase.UBA KA1,TM=M„ 375
431696, AA259068, Hs 267819, protein phosphatase 1, regulatory (inhibitor) subunit 2, none,SS=M, 375 444184, T87841, Hs 282990, Human DNA sequence from clone RP1-28H20 on chromosome 20q13 1 Contains part of a gene for a novel protein similarto membrane transport proteins, the 5' end of a novel gene, ESTs STSs, GSSs and three CpG islands, pkιnase,RI01 ,APH,KOW,TM= , 375 405411, , , ENSP00000252213 SODIUM BICARBONATE COTRANSPORTER , none TM=Y,SS=M, 375 405602, , , Target Exon pkιnase,SS=M, 375 429355, AW973253 Hs 292689, ESTs, pkmase,bZIP,Armadιllo_seg,none, 375
430153, AW968128, Hε 336679, ESTs, pkinase.none, 374
414180, AI863304, Hs 120905, Homo sapiens cDNA FLJ11448 fiε, clone HEMBA1001391, PI3_PI4_kιnase,PI3Ka,PI3K_C2,PI3K_rbd,PI3K_p85B none 374 432236, AA531132 , gb nj47h06 ε1 NCI_CGAP_Pr9 Homo εapienε cDNA clone, mRNA sequence, pkinase.none, 374
433390, AA586950, Hs 260180, Homo sapiens mRNA cDNA DKFZp761G18121 (from clone DKFZp761G18121), complete eds, none,spxtπn,SH3 PH.CH, 374 426485, NM_006207, Hs 170040, platelet-derived growth factor rxeptor-like ιg,SS=M 374
408414, AI114688, Hs 17998, ESTs, Weakly similar to 2109260A B cell growth factor [H sapiens] fn3,ιg,TM=Y,SS=M, 373 409793, AI825463 Hs 147996, protein kinase, X-lmked, pkmase,pkιnase_C,TM-M„ 373 412456, T32689, Hs 7859, ESTs, BAG.none, 3 73
407894, AJ278313, Hs 41143, phosphoinositide-specific phospholipase C-beta 1, C2.PI PLC-Y,PI-PLC-X,TM=M„ 373 442229, AI885776, Hs 8164, Mulibrey nanism, MATH,DENN,GRAM,zf-B_box,dDENN,uDENN,SS=M, 373
450151, AI088196, Hs 22968, Homo sapienε clone IMAGE 451939, mRNA sequence, ιg,pkιnase,πoπe, 372 408331, NMJ07240, Hs 44229, dual spxificity phosphatase 12, DSPc,TM=M„ 372 417821, BE245149, Hs 82643, protein tyrosine kinase 9, cofilm_ADF,SS=M, 372
403391, , , C3001164* gι|1730196Isp|P50573|GAR3_RAT GAMMA-AMINOBUTYRIC-ACID RECEPTOR RHO-3 SUBUNIT PRE, πone,TM=Y„ 372 417527, AA203524, , gb zx56e10 Soares.fetal.liver.spleenJ NFLS_S1 Homo εapienε cDNA clone 5', mRNA sequence, SH3,SS=M, 371
428428, AL037544, Hs 184298, cyclm-dependent kinase 7 (homolog of Xenopus M015 cdk-activat g kinase), pkιπase,TM=M„ 371 428180, AI129767, Hs 182874, guanine nucleotide binding protein (G protein) alpha 12, G-alpha arf,TM=M„ 371 422127, AW504286 Hs 112049, SET binding factor 1, dDENN.DENN.GRAM PH.SS-M, 370 430570, AI417881, Hs 292464, ESTs, 7tm_2,Fz,Fπzzled,none, 370 452561, AI692181, Hs 49169, KIAA1634 protein, TPR,PDZ,WW,Guaπylate_kιπ,TM=M„ 369
432336, NM_002759, Hs 274382, protein kinase interferon inducible double stranded RNA dependent, dsrm,pkιnase,TM=M„ 369 419945, AW290975, Hs 118923, ESTs, SH3,PDZ,Guanylate_kιn,transfemn 369 426539, AB011155, Hε 170290, discs, large (Drosophila) homolog 5, SH3,PDZ,Guanylate_kιn,TM=M„ 368 436534, AA721628, Hs 191958, immunoglobulin superfamily rxeptor traπslxation assxiated 2, ιg,TM=Y,SS=M, 368 407202, N58172, Hs 109370, ESTε, F5 F8_type pkmaεe.Etε.none, 367
420297, AI628272, Hs 88323, ESTs, Weakly simϋar to ALU1.HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens) pkιnase,TUDOR,none,
367 417863, AB000450 Hs 82771, vaccinia related kinase 2, pkιnase,TM=M„ 367
425304, AA463844, Hs 31339, fibroblast growth fxtor 11 , FGF,Neur_chaπ_LBD,Neur_chan_memb,none, 367 418318, U47732, Hs 84072, transmembrane 4 εuperfamily member 3, tranεmembrane4,TM=Y,SS=M, 367
419511, AA429750, Hs 75113, general transcnption fxtor IIIA, Glypican.none, 366 424315, AW614850, Hε 193384, putatative 28 kDa protein, none.none, 366 413076, U10564, Hs 75188, weel (S pombe) homolog, pkιnase,TM=M„ 366
425838, NM.014071, Hs 159613, nuclear receptor coxtivator RAP250, peroxisome proliferator-xtivated rxeptor interxting protein, thyroid hormone rxeptor binding protein, none,TM=M„ 365
446983, AA157484, Hs 97199, complement component C1q rxeptor, EGF,lxtιn_c,Tιssue_fx,Xlιnk,TIL,TM=Y,SS=M, 365 434350, AL042940, Hs 93872, KIAA1682 protein, none.none, 365
457317, AA683016, Hs 12210, hypothetical protein FLJ13732 similar to tensm, SH2,TM=M„ 365 434416, AA805903, Hs 59498, ceil division cycle 2-lιke 5 (cholinesteraεe-related cell division controller), pkinase.none, 365 410174, AA306007, Hs 59461, DKFZP434C245 protein, noπe.DSPc, 365
423598, BE247600, Hε 155538, ESTε, 7tm_1,TM=Y,SS=M, 365 440861, BE244115, Hε 7482, KIAA0682 gene product, rrm,Guanylate_kιn,TM=M„ 364 454954, AW993013, Hs 49169, KIAA1634 protein, TPR,PDZ,WW,GuanyIate_kιn,TM=M„ 364 430250, NM.016929, Hs 283021 , chloπde intracellular channel 5, none,TM=M„ 364 450587, AI828854, Hs 258538, stπatm, calmodulin-bmding protein, pkιnase,WD40,TM=Y„ 364
424893, AW295112, Hs 153648, Homo sapienε cDNA FU13303 fis, clone OVARC1001372, highly similarto Homo sapiens Iιpπn-alpha4 mRNA, SAM,SS=M, 364 425645, AA361027, , gb EST70242 T-cell lymphoma Homo sapiens cDNA 5' end, mRNA sequence, HMG_box,DNA_mιs_repaιr,HATPase_c,none 364 417426, NM 002291, Hs 82124, laminin, beta 1, laminin EGF,lamιnιn_Nterm,ιntegπn_B,SS=M, 363 451292, AB037716, Hs 26204, KIAA1295 protein, SH3,TM=M„ 363 412314, AA825247, Hs 250899, heat shxk fxtor binding protein 1, 7tm_1,TM=Y,SS=M, 363
418303, AA215701, Hs 186541, ESTε, Weakly similarto I38022 hypothetical protein [H sapiens], elF5_elF2B,W2,pkmase,UBA,KA1, 363 452716, AI914925, Hs 222240, ESTs, SH2,STAT,STAT_bmd,STAT_prot,none, 363
403869, , , NM.004520* Homo sapiens kinesm heavy chain member 2 (KIF2), mRNA member 3 (KCNQ3), mRNA , kmesιn,TM=M„ 363
450377, AB033091, Hs 74313, KIAA1265 protein, Zιp,TM=M,SS=M, 363 417793, AW405434, Hε 82575, small nuclear πbonucl∞protein polypeptide B", rrm,TM=M„ 363
404942, U30825, , splicing fxtor, argmme/seπne-πch 9, CD36,TM=Y,SS=M, 363 429554, NM 012275, Hs 207224, interleukin 1, delta, IL1,TM=M„ 363 417871, AA521368, Hs 24252, ESTs, IBB,Armadιllo_εeg,none, 362
437672, AW748265, Hs 5741 , flavohemoprotem b57, heme.1 ,NAD_bιndmg,lιpoxygenase,FAD_bιndιng_6,TM=M„ 362 438698, AW297855, Hs 125815, ESTs, Weakly similar to I38022 hypothetical protein [H sapiens], lipoxygenase.PLAT.none, 362
447217, BE465754, Hs 17778, neuropilm 2, CUB,MAM,F5_F8_type_C,TM=M,SS=M, 361
407961, AW672939, Hs 41694, oπgin recognition complex, subunit 2 (yeast homolog)-lιke, none,pkιnase,pro_ιεomerase, 361 428840, M15990, Hs 194148, v-yes-1 Yamaguchi εaraoma viral oncogene homolog 1, SH2,SH3,pkιnase,SS=M, 361 455608, BE011437, , gb CM4-BN0220-080500-170-f03 BN0220 Homo sapiens cDNA, mRNA sequence, none,CDK5.xtιvator, 361 407748, AL079409, Hs 38176, KIAA0606 protein, SCN Orcadian Oscillatory Protein (SCOP), PP2C,LRR,PH,TM=M„ 360
421474, U76362, Hs 104637, solute camerfamily 1 (glutamate transporter), member 7, SDF,TM=Y,SS=M, 360 449987, AW079749, Hε 184719, ESTε, Weakly similar to ALU1.HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H εapiens],
ABC_tran,ABC_membrane,ιon_tranε, 360 403142, , , NM.002706* Homo sapiens protein phosphatase 1 B (formerly 2C), magnesium dependent, beta isoform (PPM1B), mRNA , PP2C,TM=M„ 360 400844, , , NM.003105* Homo sapiens sortilm related rxeptor, L(DLR clasε) A repeatε-coπtainmg (SORL1), mRNA ,
EGF,fn3,ldl_recepLa,ldl_recepLb,granulιn,BNR,TM=Y,SS=M, 359 450152, AH 38635, Hs 22968, Homo sapiens clone IMAGE 451939, mRNA sequence, ιg,pkιnase,none, 359 429782, NM_005754, Hs 220689, Ras-GTPase-xtivatmg protein SH3-domam binding protein, rrm NTF2,TM=M„ 359 436469, AK001455 Hs 5198, Down syndrome critical region gene 2, none,SS=M, 359 437400, AB011542, Hs 5599, EGF-like domain multiple 5, TNFR c6,lamιnm_EGF,TM=Y„ 358
426797, AW936258, Hs 342849, ADP-nbosylation fxtor-like 5, arf,Ca_channel_B,SH3, 3 58 431170, AW971246 Hs 291022, ESTs, LRR,CARD,none, 358 434542, AA769310 Hs 61260, hypothetical protein FLJ13164, PH,Oxysterol_BP,TM=M,SS=M, 358 420181, AI380089, Hs 158951, ESTs, none.ig pkmase.LRR LRRCT, 357
450572, AI700863, Hs 202494, Homo sapiens cDNA FLJ13245 fis, clone OVARC1000681, Na.sulph.εymp.none, 357 433618, AA602539, Hs 345494, ESTs, G-alpha,A_deammaεe, 357
452695, AW780199, Hs 30327, mitogen activated protein kinase xtivated protein kinase 5, pkinase.none, 3 57 418512, AW498974, , diacylglycerol kinase, zeta (104kD), ras.πone, 357
451752, AB032997, Hs 26966, KIAA1171 protein, ATP-synt_C,TBC,TM=Y,SS=M, 357 417129, AI381800, Hs 300684, calcitonin gene-related peptide receptor component protein, none.none, 357
449474, AA019344, Hs 2055, ubiquitin activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing), ThιF,UBACT,pkιnase,UCH 2.UCH 1,rrm,zf C2H2,zf- RanBP.G patch, 357 412124, H43378, Hε 288550, Homo εapienε cDNA FLJ23156 fis, clone LNG09609, none.none, 356 435021, AA922192, Hs 54709, ESTs, EPH_lbd,pkιnase,fn3,SAM,none, 356
431341, AA307211, Hs 251531, proteasome (prosome, mxropain) subunit, alpha type, 4, proteasome,TM= , 356 437387, AI198874, Hs 28847, AD026 protein, none,7tm_1,WD40, 3 56 422583, AA410506, Hs 27973, KIAA0874 protein, ank,G-alpha,TM=M„ 356 452102, U04343, Hs 27954, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen), none,TM=Y,SS=M, 356
420112, NM.005109, Hs 95220, oxidative-streεs responsive 1, pkιnase,TM=M„ 355 437639, AA827712, Hs 291880, ESTs, SH3,none, 355
457500, NM_002759, Hs 274382, protein k ase, interferon-inducible double stranded RNA dependent, dsrm,pkmase,TM=M„ 355 415660, AI909007, Hε 78563, ubiquitin-conjugatmg enzyme E2G 1 (homologous to C elegans UBC7), UQ_coπ,TM=M„ 355 423393, R37772, Hs 21420, p21-xtιvated protein kinase 6, pkιnase,PBD,TM=M„ 355
428727, AF078847, Hs 191356, general transcnption fxtor 1IH polypeptide 2 (44kD subunit), PH04,LIM,TM=M„ 355 411190, AA306342, Hs 69171, protein kinase C-like 2, pkιnase,pkιnase_C,HR1 ,TM=M„ 355 408683, R58665, Hs 46847, TRAF and TNF rxeptor-asεociated protein, Exo_endo_phos,TM=M„ 355
412350, AI659306, Hs 73826, protein tyrosine phosphatase, non rxeptor type 4 (megakaryocyte), Y_phosphatase,Band_41 ,PDZ,TM=M„ 355 446742, AA232119, Hs 16085, putative G-protem coupled receptor, none,TM=Y,SS=M, 355
427283, AL119796, Hs 174185, xtonudeotide pyrophosphatase/phosphodiesterase 2 (autotaxm), Sulfatase,Somatomedm_B,Phosphodιest,Endonuclease,TM=M,SS=Y, 3 55 414888, AL039185, Hs 77558, thyroid hormone receptor mterxtor 7, HMG14_17,noπe, 355 424848, AI263231, Hs 327090, EST, SH3,PDZ,Guanylate_kιn,none, 354
402704, , , C1001099' gι|6005896|ref|NP_009101 1| testis-εpxific protein kinase 2 [Homo sapiens] gι|4, none.none, 354 444099, D87432, Hs 10315, solute earner family 7 (cationic ammo xid transporter, y εystem), member 6, aa_permeases,TM=Y,SS=M, 354 429687, AI675749, Hs 211608, πucleopoπn 153kD, zf-RanBP,ιntegπn_B,TM=M , 353 413879, AA132961, Hs 212533, Homo sapiens cDNA FLJ22572fis, clone HSI02313, none.none, 353
431045, AW968560, Hs 301957, nudix (nucleoside diphosphate linked moiety X)-type motif 5, NUDIX,sxY,E1_dehydrog transket_pyr,TM=Y,SS=M, 353 423855, AA331761 , Hε 254859, ESTs, none,pkιnase,UQ_con,vwa,FG-GAP,ιntegπn_A, 353 440682, AW362152, Hs 27181 , nuclear receptor binding fxtor-2, cyclιn,bZIP,TM=M„ 352
410686, AI733735, Hs 114905, IRE1, S cerevisiae, homolog of, pkιnase,Bxteπal.PQQ,TM=M,SS=M, 3 52 449810, AB008681 , Hs 23994, xtivm A rxeptor, type HB. pkιnase,Actιvιn_rxp,TM=Y,SS=M, 352 418755, Y14443, Hs 88219, zme finger protein 200, zf-C2H2,zf BED,TM=M„ 352 448804, AW512213, Hs 342849, ADP-nbosylation fxtor-like 5 arf,Ca_channel_B,SH3, 352 438507, AA809052, Hs 182018, ESTs, none.none, 352
456559, AI336273, Hs 102548, gluc∞orticoid receptor DNA binding fxtor 1, noπe.PAS, 351
410054, AL120050, Hs 58220, Homo sapiens cDNA FLJ23005 fis, clone LNG00396, highly similar to AF055023 Homo sapienε clone 24723 mRNA εequence,
RasGAP.adenylatekmase, 351 422321, AA906427, Hs 181035, hypothetical protein MGC11296, none,TM=M„ 351 445701, AF055581, Hs 13131, lymphxyte adaptor protein, SH2,PH,TM=M„ 350
407393, AB038237, , gb Homo sapienε mRNA for G protein-coupled rxeptor C5L2, complete cdε , 7tm_1 ,TM=Y,SS=M, 350 443303, U67319, Hε 9216, caspase 7, apoptosis-related cysteine proteaεe, pkinase,ICE_p10,ICE_p20,TM=M,SS=M, 350 420673, AB008112, Hs 99847, peroxisome biogenesiε fxtor 1, AAA,APS_kιnase,TM=M,SS=M, 349 424663, NM.002351, Hs 151544, SH2 domain protein 1A, Duncan's diseaεe (lymphoproliferative εyndro e), SH2,TM=M„ 349 429327, AA283981, Hε 199248, prostaglandin E rxeptor 4 (subtype EP4), 7tm_1,TM=Y,SS=M, 349 400178, , , Eos Control, none.Somatomedm.B, 349 439549, AW937885, Hs 137314, ESTs, SH2,πoπe, 349
436345, AA873008, Hε 121572, ESTs, CARD,BIR,zf-C3HC4,CARD,BIR,zf-C3HC4, 349 427658, H61387, Hs 30868, nogo rxeptor; LRR,LRRNT,LRRCT,SS=M, 348 402833, , , C1002508 gι|6691937|emb|CAB65797 1| (AL096770) bA150A62 (novel 7 transmembrane rxeptor; none.none, 348
442363, AI337304, Hs 23120, PIST, fn3,pkιπase,PDZ,DUF139,TM=Y,SS=M, 348 409132, AJ224538, Hs 50732, protein kinaεe, AMP-xtivated, beta 2 non-catalytic εubunit, none,TM=M„ 347 417971, Y08991, Hs 83050, phosphoιπosιtιde-3-kιnase, regulatory subunit 4, p150, pkιnase,WD40,HEAT,SS=M, 347 432169, Y00971, Hs 2910, phosphoπboεyl pyrophosphate synthetase 2, Pπbosyltran,, 347 447425, AI963747, Hs 18573, xylphosphatase 1, erythrocyte (common) type, Acylphosphatase,SS=M, 347 427231, AW851989, Hs 285814, sprauty (Drosophila) homolog 4, SH2,SH3,TM=M,SS=M, 346
401851, , , NM.002401* Homo sapienε mitogen-xtivated protein kinaεe kinase kinase 3 (MAP3K3), mRNA , pkιnase,SS=M, 346
407877, AW016811, Hs 234478, Homo sapiens cDNA FLJ22648fis, clone HSI07329, pkιnase,pkιπase_C,none, 345 432279, N95104, Hs 274260, ATP-binding cassette, sub-family C (CFTR/MRP), member 6, ABC_tran,ABC_membrane,none, 345 437103, AW139408, Hs 152940, ESTs, Choline kmase.πone, 345
420338, AA825595, Hs 88269, Homo sapiens, clone MGC 17339, mRNA, complete eds, 7tm_1,TM=Y,SS=M, 344 422209, AF005210, Hs 113222, chemokine (C-C motif) rxeptor 8, 7tm_1,7tm_2,TM=Y,SS=M, 344 410781, AI375672, Hs 165028, ESTε, pkmase,lamιnιn_Nterm,lamιnιn_EGF,cyclιn,F-box,cyclιn_C,εerpιn,ATP-synLC, 344 437296, AA350994, Hs 20281, KIAA1700, Rhodaneεe,DSPc,TM=M„ 343 419855, AI935182, Hs 144139, ESTs, zf-C3HC4,UBA,Cbl N.Cbl N2,Cbl N3,zf-C3HC4,UBA,Cbl N,CbI_N2,Cbl N3, 343
433336, AF017986, Hs 31386, sxreted fπzzled related protein 2, Fz,NTR,SS=M, 343 428483, AI908539, Hs 184592 KIAA0344 gene product, none.none, 343
445119, AF035121, Hs 12337, kinase insert domain rxeptor (a type III rxeptor tyrosine kinase), ιg,pkιnase,TM=Y,SS=M, 342 454468, AI590319, Hs 19122, eukaryotic translation initiation fxtor 4E-lιke 3, none,Neur_chaπ_LBD,Neur_chan_memb,IF4E, 342 410386, W26187, Hs 3327, Homo sapiens cDNA FLJ22219 fis, clone HRC01637, pkιnase,Guanylate_km,PDZ,SH3,L27,none, 342
422907, AI879263, Hε 77273, Human glucose transporter pseudogene, none.none, 342 449816, AI701457, Hs 38694, ESTs, SET,BAH,PK,PK_C, 342
440074, AA863045, Hs 10669, ESTs, Weakly similar to T00050 hypothetical protein KIAA0400 [H sapienε] SH3,ank tubulin bιπdιng,ArfGap,PH,TM=M,SS=M, 342 425475, W56339, Hε 107057, ESTε, pkinase.none, 342 401242, AB028989, , mitogen-xtivated protein kinase 8 interacting protein 3, Cys_knot,TGF-beta,vwa,vwc,vwd,TIL,DUF139,SS=M, 341
429276, AF056085 Hs 198612, G protein-coupled rxeptor 51, 7tm_3 ANF_rxeptor,bZIP,TM=Y„ 341 445800, AA126419, Hs 32944, mositol polyphosphate-4-phosphatase, type 1, 107kD, none.none, 341 410908, AA121686, Hs 10592, ESTs, GTP_EFTU,GTP_EFTU_D3,GTP_EFTU_D2 none, 341 452960, AK001335, Hs 31137, protein tyrosine phosphatase, receptor type, E, Y_phosphatase,πone, 340
447898, AW969638 Hs 112318, 62 kd protein, none.none, 340
450402, BE218027, Hs 89969, ESTs, SH3,πoπe, 340
441466, AW673081, Hs 54828, ESTs, pkιnase,zf-C2H2,KRAB,none, 340 408546, W49512, Hs 46348, bradykinin receptor B1, 7tm_1,TM=Y,SS=M 340
410927, T77635, , gb yc91 h06 r1 Soares infant brain 1 NIB Homo sapienε cDNA clone 5', mRNA sequence, none.none, 340
409646, AW161391, Hs 709, deoxycytidme kinase, dNK,SS=M, 339
417165, R80137, Hs 302738, Homo εapiens cDNA FLJ21425fis, clone COL04162, Sulfate_traπsp,STAS,HMG_box, 339
449343, AI151418 , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineuπn A alpha), none none, 339 450511 , R07423, Hs 85092, thyroid hormone receptor interactor 11 , Myosin.tail.EGF, 339
414271, AK000275, Hs 75871, protein kinaεe C binding protein 1, bromodomaιn,PHD,PWWP,zf-MYND,TM=M„ 3 38
418428, Y12490, Hs 85092, thyroid hormone receptor interactor 11 , bZIP,kιnesιn,GTP_cyclohydrol,M,TM=M„ 337
422369, AF005216, Hε 115541, Januε kinaεe 2 (a protein tyrosine kinase), SH2,pkmase,TM=M„ 337
456451 , AI761180, Hε 94211 , rcdl (required for cell differentiation, S pombe) homolog 1 , πone,TM=M„ 337 5 438543, AA810141, Hs 192182, ESTs, SH2,pkιπase none, 337
401943, NM.012434, , solute earner family 17 (anion/sugar tranεporter), member 5, none,TM=M„ 3 36
415276, U88666, Hs 78353, SFRS protein kinase 2, pkιnase,TM=M„ 336
447881, BE620886, Hε 75354, GCN1 (general control of ammo-acid synthesis 1, yeast)-lιke 1, pkinase.pkinase, 3 35
434533, AA639257, Hs 292549, ESTs, SH3,PDZ,Guanylate_kιn,none, 335 0 432639, AW973785, , gb EST385886 MAGE resequences, MAGM Homo sapiens cDNA, mRNA sequence, none.IRK, 335
410678, BE540516, Hε 293732, hypothetical protein MGC3195, Armadιllo_εeg,TM=M,SS=Y, 335
402807, , , ENSP00000235229 SEMB , ιntegπn_B,Sema,PSI,TM=Y„ 335
420189, AW296380, Hε 95821, osteoclast stimulating factor 1, SH3,ank„ 334
437389, AL359587, Hs 271586, hypothetical protein DKFZp762M115, sxY,E1_dehydrog,transket_pyr,none, 334 5 453423, NM.002647, Hs 32971, phosphoιnosιtιde-3-kιπase, class 3, PI3_PI4_kιnase,PI3Ka,PI3K_C2,TM=M„ 334
414270, L20852, Hs 347527, solute earner family 20 (phosphate transporter), member 2, Enterotoxιn_A,PH04,TM=Y,SS-M, 333
417479, AI057052, , ESTε Weakly similar to Z195_HUMAN ZINC FINGER PROTEIN 195 [H sapiens], LRR,CARD,noπe, 333
424946, M64572, Hs 153932, protein tyrosine phosphatase, non receptor type 3, Band_41,PDZ,Y_phosphatase,none, 333
452681, AF153330, Hs 30246, solute earner family 19 (thiamine transporter), member 2, Folate_camer,TM=Y,SS=M, 333 O 426477, AA379464, , gb EST92386 Skin tumor I Homo sapienε cDNA 5' end, mRNA sequence, DUF6,MATH,BTB, 333
438283, AI458931, Hs 37282, ESTs, none,transmembraπe4, 333
421327, AA837295, Hε 188802, ESTε, none,IMP4,Y_phosphatase, 333
432481, AW451645, Hs 151504, Homo εapienε cDNA FLJ11973 fis, clone HEMBB1001221, lamιnιn_G,Collagen,COLFI CorA.TSPN.none, 333
452682, AA456193, Hs 9071 , progesterone membrane binding protein, homeobox.none, 332 5 428997, AF065391, Hs 194718, zinc finger protein 265, zf-RaπBP,TM=M„ 332
432211, BE274530, Hs 273333, hypothetical protein FLJ10986, FGGY_C,TM=M„ 331
443601, AI078554, Hs 15682, ESTε, ank,pkιnaεe,death,Rιboεomal_S14, 331
430597, AF062006, Hs 285529, G protein-coupled rxeptor 49, 7tm_1,LRR,LRRNT,TM=Y,SS=M, 3 31
419912, AF249745, Hs 6066, Rho guanine nuclxtide exchange fxtor (GEF) 4, SH3,PH,RhoGEF,TM=M„ 331 0 400380, NM 18485, Hs 283079, G protein-coupled rxeptor C5L2, 7tm_1,TM=Y,SS=M, 3 31
415983, AI436798, Hs 117078, Homo sapiens cDNA FLJ23028 fis, clone LNG01852, highly similarto HSU08023 Human cellular proto-oncogene (c-mer) mRNA, fn3,ιg,pkιnase,TM=Y,SS=M, 331
441054, AA913591, Hs 126480, ESTs, πone,7tm 1, 3 31
418342, BE002723 , leptin rxeptor, ICE_p20,DED,ICE_p10,ICE_p20,DED, 331 5 446128, AW836779, Hs 113029, πbosomal protein S25, none,7tm_1, 331
425086, AW957571, Hs 12319, Homo εapienε cDNA FLJ12774 fis, clone NT2RP2001663, moderately similar to ENOLASE (EC 42 1 11), none.Guanylate kιn,PDZ,SH3, 3 31
425725, NM.012243, Hs 159322, solute earner family 35 (UDP-N-xetylglucosamine (UDP-GlcNAc) tranεporter), member 3, DUF6,TM=Y,SS=M, 330
422608, AW160644, Hs 118695, potassium voltage-gated channel, subfamily G, member 1, ιon_traπs,K_tetra,TM=Y„ 330
429061, Y14039, Hε 195175, CASP8 and FADD-like apoptoεiε regulator, ICE_p20,DED,TM=M„ 330 O 433656, AW974941 , Hs 292385, ESTs, Weakly similar to I78885 seπne/threonine-εpxific protein kmase [H sapienε], pkιnase,ABC1 ,none, 330
413132, NM_006823, Hs 75209, protein kinase (cAMP-dependent, catalytic) inhibitor alpha, PKI,SS=M, 330
402603, , , ENSP00000251206* KIAA0778 PROTEIN (FRAGMENT) , none,TM=Y„ 330
418801, AA228366, Hs 115122, ESTs, integnn A,FG-GAP,πone, 330
400275, , , NMJ06513* Homo sapiens seryl-tRNA synthetase (SARS), mRNA (SAM68), mRNA , tRNA-synL2b,Seryl_tRNA_N,TM=M„ 3 29 5 440286, U29589, Hs 7138, cholmergic rxeptor, muscannic 3, 7tm_1,TM=Y„ 329
409101, NM.004297, Hs 50612, guanine nucleotide binding protein (G protein), alpha 14, G-alpha,none, 329
432736, AA788898, Hs 179902, transporter-like protein, none,TM=Y,SS=M, 329
408738, NMJ14785, Hs 47313, KIAA0258 gene product, none,TM=M„ 329
443195, BE148235, Hs 193063, Homo sapienε cDNA FU14201 fiε, clone NT2RP3002955, Aa ranε.none, 329 0 405328, , , NM.005391 Homo εapieπs pyruvate dehydrogenase kinase, isoenzyme 3 (PDK3), mRNA , HATPase_c,SS=M, 328
418764, N30531, Hs 42215, protein phosphatase 1, regulatory subunit 6, none.none, 328
408756, AA524743, Hs 44883, ESTs, Armadιllo.seg,IBB,DEAD,helιcase_C,Sx63,DDT,PHD,bromodomaιn,TM=M„ 328
415474, NM_014252, Hs 78457, solute earner family 25 (mitxhondπal earner, ornithine transporter) member 15, mιto_carrTM=M„ 328
417805, U38545, Hs 82587, phospholipase D1, phophatidylcholiπe-spxific, PH,PLDc,PX,TM=M„ 328 5 410254, BE004131, Hs 318510, Homo εapiena cDNA FLJ13682fiε, clone PLACE2000015, weakly εimilar to EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE
SUBSTRATE 15, efhand.none, 328
443968, AA287702, Hε 10031, KIAA0955 protein, CARD,TM=M,SS=M, 328
438899, AF085833, Hε 135624, ESTε, none,PI3.PI4 kιnaεe,PI3Ka,PI3K_C2,PI3K_rbd,PI3K_p85B, 327
415663, AW296841, Hε 313332, ESTε, UQ_con,Neur_chan_LBD,Neur_chan_memb, 327 0 414087, W19712, , gb zb36d03 r1 Soareε_parathyroιd_tumor_NbHPA Homo εapiens cDNA clone 5', mRNA sequence, pkinase.none, 327
442833, AA328153, Hε 88201 , ESTε, Weakly similar to A Chain A, Crystal Structure Of The Human Acyl Protein Thioesterase 1 At 1 5 A Resolution [H εapiens], abhydrolase_2,TM=M„ 327
444754, T83911 , Hs 11881 , transmembrane 4 superfamily member 4, none,TM=Y,SS=M, 326
432579, AF043244, Hs 278439, nucleolar protein 3 (apoptosiε repreεsor with CARD domain), CARD,TM=M„ 326 5 458943, AW249181, Hs 19954, ESTs, Weakly similar to T19873 hypothetical protein C41C42- Caenorhabditiε elegans [C elegans], none,pkιnase,RGS, 326
411974, AW880414, Hs 84264, xidic protein πch in leucines, E1-E2_ATPase,Catιon_ATPase_C,Catιon_ATPase_N,Hydrolase,asp, 326
437145, AF007216, Hs 5462, solute earner family 4, sodium bicarbonate cotransporter, member 4, HC03_cotransp,TM=Y„ 3 26
423387, AJ012074, , vasoactive intestinal peptide receptor 1, 7tm_2,HRM,CSD,TM=Y,SS=M, 325
442643, U82756, Hs 3991 , PRP4/STKΛ/VD splicing factor, WD40,SS=M, 325 0 417525, R93355, Hs 192991, ESTs, Weakly similar to ALUB_HUMAN "» ALU CLASS B WARNING ENTRY l" [H sapiens] SH3,ιg,pkιπase PH spectπn,RhoGEF,SS=M, 325
412283 BE069084, , gb QV3 BT0379 140100 05a-g12 BT0379 Homo sapiens cDNA, mRNA sequence, lon.trans.RYDR ITPR,MIR,none, 325 411213, AA676939, Hs 69285, neuropilm 1, MAM,F5_F8_type_C,CUB,CUB,MAM,F5_F8_type_C, 3 25 400352, AF227133, , taste rxeptor, type 2, member 7, noπe,TM=Y,SS=M, 3 25 402974, , , Target Exon, Y_phosphatase,GnRH,hormone5,hormone4, 325
407644, D16815, Hs 37288, nuclear receptor subfamily 1, group D, member 2, hormone_rx,zf-C4,TM=M,SS=M, 325
421654, AW163267, Hs 106469, εuppreεεor of varl (S cereviεiae) 3-lιke 1, helιoase_C,SS=M, 3 25
438022, AW517524, Hs 135201, NOD2 protein, LRR,CARD,GTP_CDC,Viral_fιelιcase1,TM=M, 324 449964, AW001741 , Hs 24243, hypothetical protein FLJ10706, pkιnase,TM=M„ 3 24
428816, AA004986, Hs 193852, ATP-bindmg casεette, sub-family C (CRR/MRP), member 2, EGF,suεhι,trypsm,CUB,ABC_tran,ABC_membrane,SS=M, 3 24
427319, AW631495, Hs 27135, B-cell rxeptor-assxiated protein BAP29, filament,TM=Y,SS=M, 3 24
421970, AF227156, Hs 110103, RNA polymerase I transcnption fxtor RRN3, aa_permea8eε,pyπdoxal_deC,bromodomaιπ,PHD,MBD,AT_hook,DDT,PI3_PI4_kιnaεe FAT,FATC,BolA,RUN TM=M„ 324 411887, AW182924, Hs 128790, ESTs, pkιnase,TM=M„ 324
430180, AA331406, Hs 75456, A kinase (PRKA) anchor protein 10, RGS,SS=M, 324
410267, AW978005, Hs 12600, N ethylmaieimide senεitive fxtor attachment protein, beta, none,NTF2, 323
410240, AL157424, Hε 61289, synaptojanm 2, Exo endo phos,Syja_N,rrm,Gram ve_poπnε,TM=M„ 323
434510, AF143885, Hε 18190, EST, SH3,FCH,none, 322~ 422592, BE081857, Hs 94211, rcdl (required for cell differentiation, S pombe) homolog 1 , none,PI-PLC-X,PH PI-PLC-Y.C2, 322
439803, AA001021, Hs 6685, thyroid hormone receptor interactor 8, none.none, 322
448520, AB002367, Hs 21355, doublxortm and CaM kinase like 1, pkιnase,DCX,TM=M„ 322
409245, AA361037, Hs 288036, tRNA isopentenylpyrophosphate transferase, Armadιllo_seg,TM=M„ 322
458946, AA009716, Hε 42311, ESTε, noπe,DSPc,Y_phosphatase, 322 409048, H59990, Hs 37699, ESTs, Armadιllo_seg,IBB,none, 322
420357, U94333, Hs 97199, complement component C1q receptor, EGF,lectιn_c,Tιssue_fx,Xlιπk,TIL,TM=Y,SS=M, 3 22
426230, AA367019, Hs 241395, proteaεe, εeπne, 1 (trypsin 1), trypsιn,toxιn_4,SS-M, 3 21
411352, NM.002890, Hs 758, RAS p21 protein activator (GTPase xtivatmg protein) 1, SH2,SH3,C2,PH,RasGAP,TM=M,SS=M, 321
438333, R39382, Hs 25283, cyclm-dependent kinase 8, pkinase.none, 320 414202, BE275653, Hs 270379, transmembrane 6 superfamily member 1, 7tm_5,none, 320
429651, D79248, Hs 279870, ESTε, Weakly similar to A46010 X-lmked retmopathy protein [H sapienε], MgtE.none, 3 20
400987, , , C11000939 gι|11464993|ref|NP_065260 11 gene for odoraπt rxeptor MOR83 [Mus musculuε] gι|6 noπe,TM=Y,SS=M, 320
413760, Z25101, Hε 25127, Homo εapienε mRNA for KIAA1725 protein, partial cdε, none.ank.ArfGap, 320
408468, AI909712, Hε 93837, phoεphatidylmositol transfer protein, membrane-assxiated, PX,PH,PLDc,PH,PLDc,PX, 320 409463, AI458165, Hs 17296, hypothetical protein MGC2376, KJetra TM=M„ 320
425910, AA830797, Hs 184760, CCAAT-box-binding transcription factor, none,TM=M„ 3 19
423798, AF047033, Hs 132904, solute carrier family 4, sodium bicarbonate cotranεporter, member 7, HC03_cotransp,TM=Y,SS=M, 3 19
407753, AL045916, Hs 293419, ESTs, Ephπn.none, 3 19
419355, AA428520, Hs 90061, progesterone binding protein, heme_1,TM=Y,SS=M, 319 454128, AL031259, Hs 41639, programmed cell death 2, zf-MYND,TM=M„ 3 19
421202, AF193339, Hs 102506, eukaryotic translation initiation fxtor 2-alpha kinase 3, pkιnase,TM=Y,SS=M, 3 19
446360, N42553, Hs 267914, homolog of mouεe transient rxeptor potential phospholipaεe C-interacting kinase CHaK, hypothetical protein FLJ20117, ιoπ_trans,MHCK_EF2_kιnase,TM=M„ 3 18
458882, R34993, Hs 226666, ESTs, Moderately similar to I54374 gene NF2 protein [H εapiens] CRAL_TRIO,PKI, 3 18 424124, AA335609, Hs 7589, ESTs, Weakly similarto A46010 X-lmked retmopathy protein [H sapiens], pkinase.TBC, 3 18
444745, AF117754, Hε 11861, thyroid hormone rxeptor-assxiated protein, 240 kDa subunit, none,TM=M„ 3 18
426399, AA652588, Hs 301348, Homo sapienε cDNA FLJ13271 fis, clone OVARC1001000, SH3,HS1_rep,none, 3 18
425836, AW955696, Hs 90960, ESTε, CbLN,Cbl_N2,Cbl_N3,UBAzf-C3HC4,πoπe, 318
403335, , , NM.021815 Homo sapiens solute carrier family 5 (cholme transporter), member 7 (SLC5A7), mRNA , SSF,TM=Y,SS=M, 317 428788, AF082283, Hs 193516, B-cell CLL/lymphoma 10, CARD,TM=M„ 317
429558, AI391454, Hs 207251, nucleolar autoantigen (55kD) similar to rat synaptonemal complex protein, none,SS=M, 3 17
440248, AA876138, Hε 153136, ESTs, SH2,none, 3 17
423706, U95218, Hs 131924, G protein-coupled rxeptor 65, 7tm_1,TM=Y,SS=M, 3 17
429752, H52348, Hs 36636, ESTs, pkmaεe.pkmaεe, 3 17 446163, AA026880, Hε 25252, Homo sapiens cDNA FLJ13603 fis, clone PLACE1010270, none.NA.NA, 3 17
456773, AI038192, Hs 129764, EGF-like repeats and discoidm l-like domains 3, rrm,SH3,myosιn_head,IQ,MyTH4,EGF,F5_F8_type_C,Band_41,TM=M , 3 17
434392, AW983709, Hs 250824, Homo εapienε cDNA FLJ23435 fiε, clone HRC12631, pkinase.none, 3 16
435972, W95088, Hs 114198, ESTs, pkιnase,OPR,none, 3 16
441401, A1824338, Hs 126891, ESTs, Tisεue fx,TM=M,SS=M, 316 410497, AL157648, Hs 157078, Homo sapienε cDNA FLJ12793 fiε, clone NT2RP2002033, none.none, 3 16
401113, H25530, , εolute earner family 22 (organic cation transporter), member 1-lιke, none,SS=M, 3 16
424833, NM.003894, Hs 153405, peπod (Drosophila) homolog 2, PAS,SS=M, 3 15
453880, AI803166, Hs 28462, ESTs, Weakly similar to 138022 hypothetical protein [H sapienε], HSP70,none, 3 15
435391, AA704588, Hs 58934, ESTs, PIP5K,πone, 3 15 428065, AI634046, Hs 157313, ESTs, ICE_p20,DED,ICE_p10,ICE_p20,DED, 3 15
452688, AA721140, Hs 49930, ESTs, Weakly similar to putative p150 [H sapienε], SH3,noπe, 3 15
426839, M74782, Hs 172689, interleukin 3 rxeptor, alpha (low affinity), none,TM=M,SS=M, 3 15
421247, BE391727, Hs 102910, general transcnption fxtor HH, polypeptide 4 (52kD subunit), none,TM=M„ 3 14
440249, AI246590, Hs 249175, ESTs, TatD_DNaεe,pkιnaεe,death,πone, 314 409619, AK001015, Hε 55220, BCL2-aεsxιated athanogene 2, BAG,TM=M„ 313
446135, AW130288, Hs 170318, hypothetical protein FLJ10147, hormoπe_rx,zf-C4,SS=M, 3 13
400440, X83957, Hε 83870, nebulm, SH3,Nebulιn„ 3 12
409099, AK000725, Hs 50579, hypothetical protein FU20718, Armadιllo_seg,TM=M„ 3 12
434237, AF119908, Hs 235516, hypothetical protein PR02955, none,SS=M, 3 12 428179, AI127772, Hs 279696, ESTs, Weakly similar to I38022 hypothetical protein [H sapiens], pkmase,PX,pkιnaεe_C,SS=M, 3 12
422824, NM.012108, Hε 121128, BCR downstream signaling 1, SH2,PH,TM=M„ 3 11
409745, AA077391, , gb 7B14E12 Chromosome 7 Fetal Brain cDNA Library Homo sapiens cDNA clone 7B14E12, mRNA sequence, 7tm_1,zf C3HC4,fπ3,SPRY,KRAB,zf- C2H2,rve,zf-B box,TM=Y,SS=M, 3 11
435411, AW444619, Hε 138211, ESTε, none.pkmaεe, 311 424852, AI222779, Hs 144848, ESTs, adenylatekmase,SH2,pkιnase,πone, 3 11
441970, AW959918, Hs 155160, ESTs, rrm,zf-C2H2, 3 11
453370, AI470523, Hs 139336, ATP-bmding casεette, εub-family C (CFTR/MRP), member 4, ABC_tran,ABC_membrane,TM=Y„ 3 11
413285, BE078405, , gb QV2-BT0617-080300-071-g03 BT0617 Homo εapiens cDNA, mRNA sequence, GCV_T,SS=M, 3 10
429458, BE161832, Hs 292689, ESTs, pkιnase,bZIP,ArmadιIlo_εeg,none, 3 10 401185, , , NM_021625 Homo εapienε vanilloid receptor-related osmotically activated channel, 0TRPC4 protein (OTRPC4), mRNA , ank,ιon_trans,TM=Y„ 3 10
404537, Z25884, , chloπde channel 1 , εkeletal muscle (Thomsen disease, autosomal dominant), πone,TM=Y„ 3 10
417089, H52280, Hs 18612, Homo sapienε cDNA FLJ21909 fis, clone HEP03834, voltage.CLC.CBS.πone, 309
450792, AA400323, Hs 183041, ESTs, none,ABC_tran, 309 420361, N92054, Hs 194718 zinc finger protein 265, zf RanBP,7tm_1, 309 444040, AF204231, Hs 182982 golgm 67, SH3,C2,PH,RhoGEF,efhand,TM=M„ 309 416990, AF124145, Hs 80731 autocrme motility factor receptor, zf-C3HC4 CUE,TM=Y„ 309 442215, AI703172, Hs 129005, ESTs, Weakly similar to 2109260A B cell growth fxtor [H sapiens] none.none, 309 424187, AA336561, Hs 17287 ESTs, Weakly similarto S26689 hypothetical protein hd - mouse [M musculus] IRK.none, 309
426623, AA382826, Hs 132793, ESTs, none,TM=M„ 3 08 419577, L36531, Hs 91296 integπn, alpha 8, ιntegnn_A FG-GAP,TM=Y„ 308 426618, AL036456, Hs 171374 smg GDS ASSOCIATED PROTEIN, Armadιllo_seg,TM=M„ 308
445133, AW157646, Hε 153506, ESTs, efhand,spectrιn,GAS2,SH3,Plxtιn,RA,XyIose_ιsom,FlιD,bZIP,Tropomyosιn Myc-_Z,M,ldh_C,CH,AIP3,TM=M„ 308 423681, AB023215, Hs 131525, Homo sapienε mRNA, cDNA DKFZp434E199 (from clone DKFZp434E199), partial cdε, TTL,TM=M , 308
428730, AA625947, Hε 25750, ESTε, HECT.none, 308
427976, AW977808 Hε 80545, mitogen xtivated protein kinase 8 interxting protein 2, Rιbosomal_L37e,pkιnase, 308 412448, L12964, Hs 73895, tumor nxroεiε fxtor rxeptor εuperfamily, member 9, TNFR_c6,TM=Y,SS=M, 3 08 416814, AW192307, Hs 80042, dolichyl P-Glc Man9GlcNAc2-PP-dolιchylgIucosyltransferaεe, Alg6_Alg8,7tm_1 ,TM=Y,SS=M, 308 427395, AW298741, Hε 97861, ESTs, Moderately similar to I38022 hypothetical protein [H sapiens], none.aldedh aakinase, 308
436267, AW450938, Hs 180115, ESTs, none.PFK, 307
422309, U79745, Hs 114924, solute carrier family 16 (monxarboxylic xid transporters), member 6, sugar tr,TM=Y,SS=M, 307 439238, N47305, Hs 46668, ESTε, 7tm_1,TM=Y,SS=M, 307
458760, AI498631 , Hs 111334, ferπtin, light polypeptide, cystatιn,femtιn,hιεtone,HC03_cotranεp,SH3,RhoGAP,xan_ur_permeaεe,FCH,SS=M, 307 424236, AW058114, Hε 7837, phosphoprotein regulated by mitogenic pathways, pkιnase,TM=M„ 306
427286, AW732802, Hs 2132, epidermal growth fxtor rxeptor pathway subεtrate 8, SH3,ToπB_boxC,TM=M„ 306
423878, AI907090, Hs 52891, hypothetical protein PR01853, cystatiπ.ferπtin hιstone,HC03 cotransp SH3,RhoGAP,xan_ur_permease,FCH,SS=M 306 419270, NM.005232, Hε 89839, EphA1, fn3,pkιnase,SAM,EPHJbd,TM=M SS=M, 306
450407, NM_000810, Hs 24969, gamma ammobutyπc acid (GABA) A rxeptor, alpha 5, Neur_chan_LBD,Neur_chan_memb,TM=Y„ 306 456249, AI206144, Hs 82508, HRIHFB2206 protein, none,SS=M, 306
441560, F13386, Hs 7888, Homo sapienε clone 23736 mRNA εequence, pkιnase,Recep_L_domaιn,Fuπn lιke,YLP,none, 305 446488, AB037782, Hε 16119, KIAA1361 protein, pkιnase,SS=M, 305
447495, AW401864, Hs 18720 programmed cell death 8 (apoptosis inducing fxtor), pyr_redox,TM=M„ 305 425390, AI092634, Hs 156114, protein tyrosine phosphatase, non rxeptor type substrate 1, ιg,TM=Y,SS=M, 304 409705, M37762, Hs 56023, brain deπved neurotrophic factor, NGF,SS=M, 304
413962, AA331563 Hs 24678, sphmgosine 1-phosphatase, PAP2,TM=Y„ 304
426578, R23027, , gb yh27e07 rl Soares plxenta Nb2HP Homo sapiens cDNA clone 5', mRNA sequence, pkinase.none, 304 438005, BE151746 , gb PM1-HT0305 061299 003 a06 HT0305 Homo sapiens cDNA, mRNA sequence, pkmase,UBA,KA1 ,none, 304 438316, AA789249, Hs 80042, gb aj27g08 s1 Soares.testis.NHT Homo εapiens cDNA clone 13915823', mRNA sequence, none.none, 304 452850, H23230, Hs 22481, ESTs, Moderately similarto A46010 X-lmked retmopathy protein [H sapiens] CBS,voltage_CLC,noπe, 303
405266, , , Target Exon, arf,G-alpha,SS=M, 303 402615, , , C1003844* gι|6912550|ref|NP_0364831| olfactory receptor, family 10, subfamily J, member 1 , πone,TM=Y,SS=M, 303
422803, W28669, Hs 139041, ESTs, transmembrane4,none, 302
439325, AF086139, Hs 150423, cyclm-dependent kinaεe 9 (CDC2 related kinase), pkιnase,Mur_lιgase,Mur_lιgase_C, 302 416389, AA180072, Hs 149846, integnn, beta 5, ιntegπn_B,none, 302
418836, AI655499, Hs 161712, ESTs, pkinase.Activm rxp,PDZ,ZU5,death, 302
438996, AW748336, Hs 110613, KIAA0421 protein noπe,TM=M„ 302
422676, D28481, Hs 1570, histamine rxeptor H1, 7tm_1,TM=Y,SS=M, 302
450267, AW505538, Hs 243620, ESTs, pkinase.none, 301 400566, , , Target Exon, none,TM=Y„ 301
407816, AW500857, Hs 40137, anaphase-promotmg complex 1, meiotic chxkpomt regulator, PI PLC-X,C2,SH2,PH,SH3,PI PLC-Y,PAN,none, 301
429673, AA884407, Hs 211595, protein tyrosine phosphatase, non-rxeptor type 13 (APO-1/CD95 (Fas)-assxιated phoεphatase), Y_phosphatase,Band_41,PDZ,SS=M, 301
417067, AJ001417, Hs 81086, solute earner family 22 (extraneuroπal monoamine transporter), member 3, sugar.tr,TM=Y,SS=M, 300
403212, , , NM.019595 Homo εapiens intersxtm 2 (ITSN2), mRNA (CHRNA9), mRNA , SH3,e and,C2,PH,RhoGEF,TM=M„ 300 410141, R07775, Hs 287657, Homo sapiens cDNA FLJ21291 fis, clone COL01963, F5_F8_type_C,pkιnase,Ets,none, 300
421059, AI654133, Hs 30212, thyroid receptor interxting protein 15, none.none, 300
452335, AW188944, Hs 61272, ESTε, none.IRK, 299
437644, AA748575, Hs 136748, Ixtm-like NKcell rxeptor; l∞tιn_c,TM=Y,SS=M, 299
435876, AW612586, Hs 160271, G protein-coupled rxeptor 48, 7tm_1,LRR,LRRNT,TM=Y,SS=M, 299 429177, AA447527, Hs 207429, ESTs, 7tm_1 ,none, 299
449289, BE466067, Hs 225660, ESTs, 3Beta_HSD,pkιnase, 299
454701 , AW854930, , gb PMO-CT0263-201099-003406 CT0263 Homo sapienε cDNA, mRNA sequence, SH2,STAT,STAT_bmd,STAT_prot,none, 299
409995, AW960597, Hs 129206, ESTs, pkinase.none, 298
446860, AV660685, Hs 282953, ESTs, none,PP2C, 298 438684, AA830105, Hs 194976, SH2 domain-containing phosphatase anchor protein 1, ιg,TM=Y,SS=M, 298
434164, AW207019, Hs 148135, seπne/threonine kinase 33, pkιnase,TM=M„ 298
403290, , , C10001011* gι|4758212|ref]NP_004411 1| dual spxificity phosphatase 8 [Homo sapiens] gι|601, πone,TM=M„ 297
433556, W56321, Hs 111460, calcium/calmodulin-dependent protein kinase (CaM kinase) II delta, pkinase.none, 297
421990, T31811, Hs 110480, DC12 protein, GKAP,DUF159,TM=M„ 297 428315, AA688152, Hs 98505, ESTε, pkinaεe.none, 297
411140, AW819463, , gb RC5-ST0293-061299 031-C07 ST0293 Homo εapiens cDNA, mRNA sequence, Cholιne_kιnase,Cam_xyltransf,Sulfatase,Carn_xyltransf, 297
453998, H47802, Hs 7557, FK506-bιndιng protein 5, none.none, 297
401342, , , Target Exon, none.none, 297
453020, AL162039, Hs 31422, Homo sapienε mRNA, cDNA DKFZp434M229 (from clone DKFZp434M229), dNK,πone, 296 410976, R36207, Hε 25092, hypothetical protein MGC10744, none,TM=M,SS=M, 296
431074, BE072772, Hs 153279, ESTs, Moderately similarto A46010 X-lmked retmopathy protein [H sapiens], none.serpm, 296
443829, AI087954, Hε 23348, S-phase kinase-assxiated protein 2 (p45), F-box,none, 296
400356, AF227137, , taste rxeptor, type 2, member 13, none,TM=Y,SS=M, 295
422559, AW247696, Hs 155839, hypothetical protein MGC12934, adh_zιnc,PGK,Semιaldhyde dh,SS=M, 295 423482, BE280172, Hs 129228, galxtokmase 2, GHMP kmases,TM=M„ 295
438330, AW450572, Hs 257316 ESTs, pkinase.zf C4,ERM,CNH,none, 295
414581, AA256213 Hs 72010, ESTs, none.Carn xyltransf,Cholιne_kιnase,SC01-SenC,Glycos_tranεf_3,Glycoε_trans_3N, 295
453058, AW612293, Hs 288684, Homo sapienε cDNA FLJ11750 fiε, clone HEMBA1005568, SH2,SH3,C2,PH,RasGAP,none, 295
430556, AW967807, Hs 13797, ESTs, HECT.none, 294 400471, , , Target Exon, none,TM=M„ 294
419459, AW291128, Hs 278422, DKFZP586G1122 protein, Metallophos,7tm_1, 294
407013, U35637, , gb Human nebulm mRNA, partial eds, SH3,Nebulιn„ 294
421476, AW953805, Hs 21887, ESTs, Piwi.PAZ.Piwi 294 426806, T19228, Hs 172572, hypothetical protein FLJ20093, ank pkιnase,UPF0073,SS=M, 2 94
405588, , , NM.000299* Homo sapiens plakophilin 1 ( todermal dysplasia/skm fragility syndrome) (PKP1), mRNA , ArmadιlIo_seg,TM=M„ 294
443614, AV655386, Hs 7645, fibnnogen, B beta polypeptide, none.none, 294
416737, AF154335 Hs 79691, LIM domain protein, LIM,PDZ,TM=M„ 293 i 428522, R10184, Hs 191987, ESTs, Weakly similar to ALU1.HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H sapienε] none,ArfGap,PH,TNFR_c6 293 447818, W79940, Hs 21906 Homo sapiens clone 24670 mRNA sequence, none.pkinase, 293 432925, AA878324, , ESTs, none.none, 293
443670, AW178935, Hs 238707, ESTs, RrnaAD,DENN,dDENN,uDENN,TM=M„ 293 447555, AI391662, Hs 160963 Homo sapienε, clone MGC 12318, mRNA, complete eds, none,TM=M„ 293
435092, AL137310, Hs 4749, Homo sapienε mRNA, cDNA DKFZp761E13121 (from clone DKFZp761E13121), partial cdε, none,TM=M„ 293
417670, R07785, , gb yf15c0S r1 Soares fetal liver spleen 1NFLS Homo sapiens cDNA clone 5' similar to contains Alu repetitive element contains MSR1 repetitive element „ mRNA sequence, XYPPX,ABC_membrane,ABC_tran, 293 424148, BE242274, Hs 1741 integnn, beta 7, ιntegπn_B,EGF,metallhιo,PSI,TM=Y,SS=M, 292 439090, H65724, Hs 347158, gb yr76a11 r1 Soares fetal liver spleen 1 NFLS Homo sapienε cDNA clone 5', mRNA sequence, pkinase.none, 292
408048, NM.007203, Hs 42322, A kmase (PRKA) anchor protein 2, Paralemmιπ,TM=M„ 292
428796, AU076734, Hs 193665, solute earner family 28 (sodium-coupled nucleoside transporter), member 2, Nucleosιde_tra2,BPD_tranεp_2,TM=Y„ 292 415272, AA164215, Hε 203186, ESTε, none,Exo_endo_phθ8,BNR,Atrophιn-1,B56,pkιnase,ιg,TPR, 292 424775, AB014540, Hs 153026, SWAP-70 protein, efhand,PH,Neuregulιn,TM=M„ 292 439569, AW602166, Hs 222399, CEGP1 protein, EGF,TNFR_c6,granulιn,CUB,Keratιn B2,TIL,TM=M,SS=M, 292
441680, AW444598, Hs 7940, RAP1, GTP-GDP disεxiation stimulator 1, Armadιllo_seg,TM=M„ 291
444784, D12485, Hs 11951, xtonudeotide pyrophosphatase/phosphodiesterase 1, Somatomedιn_B,Endonuclease,Phosphodιest,TM=Y,SS=M, 291 400398, AF137396, Hs 283879, ubiquilm 3, 7tm_1 ,Abι,TM=Y,SS=M, 291 435592, AI830490, Hs 1466, glycerol kmase, FGGY,FGGY_C,TM=M„ 290 400539, , , Target Exon, none TM=M„ 290
403743, , , C1002604gι|8393668|ref]NP_058989 1| kinase interxting with leukemia-associated gene (st, none,TM=M„ 290 418913, BE046745, Hs 91579, Homo sapiens clone 23783 mRNA sequence, Y phosphatase,IMP4,none, 290 428169, AI928984, Hs 182793, golgi phosphoprotein 2, photoRC,UPF0118,TM=Y„ 290 403912, , , C5000394* gι|12737280|ref]XP_0066822| keratin 18 [Homo sapιens]||6633, none,TM=M„ 289 431868, BE246400, Hs 285176, xetyl-Coenzyme A transporter, none,TM=Y„ 289 421558, AB011125, Hs 105749, KIAA0553 protein, πoπe,TM=M„ 289
444100, AA383343, Hs 22116 CDC14 (cell division cycle 14, S cerevisiae) homolog B, Y_phosphatase,DSPc,TM=M„ 289 447437, U07225, Hs 339, punnergio receptor P2Y, G-protein coupled, 2, 7tm_1,SH2,TM=Y,SS=M, 289 431512, BE270734, Hs 2795, Ixtate dehydrogenase A, ldh,ldh_C,SH3,pkmase,UBA,TM=M„ 289 446601, AI312783, Hs 155772, Homo sapiens thymic stromal co-transporter mRNA, complete cdε, εugar_tr;TM=Y„ 289
420747, BE294407, Hs 99910, phosphofructokmaεe, platelet, PFK,TM=M„ 288 449459, BE546846, Hε 195048, ESTs, ank,ras,PH,ArfGap,HC03 cotranεp, 288 405099, , , Target Exon, C2,PI-PLC-Y,PI-PLC-X,TM=M„ 288
445890, AF055019, Hε 21906, Homo εapienε clone 24670 mRNA εequence, pkinase.pkmase, 288 401445, , , NM.021161* Homo sapiens potassium channel, subfamily K, member 10 (KCNK10), mRNA , ιon_trans,TM=Y,SS=M, 287
405480, , , Target Exon, none.none, 287 400189, , , Eos Control, LRR,PPTA,TM=M„ 287 450125, AA005418, Hs 158186, ESTs, CIDE-N,7tm_1,none, 287 432056, AB040973, Hε 272385, G protein-coupled rxeptor 72, 7tm_1 ,TM=Y,SS=M, 286 423619, T48691 , Hs 249159, adrenergic, alpha-2A-, rxeptor, 7tm_1 ,7tm_2,TM=Y,SS=M, 286
417381, AF164142, Hs 82042, solute camerfamily 23 (nucleobase transporters), member 1, xan_ur_permease,RA, 286 420035, F26725, Hs 187908, ESTs, Weakly similar to A47582 B-cell growth fxtor prxursor [H sapienε], HATPase_c,MOZ_SAS,zf-C2H2, 286 425480, AB023198, Hs 158135, KIAA0981 protein, PIP5K,SS=M, 286
446700, AW206257, Hs 156326, Human DNA sequence from clone RP11-145L22 on chromosome 6p21 32-222 Contains the gene for myelin/oligodendrocyte glycoprotein MOG, (part of) the gene for a novel KRAB box containing C2H2 type zinc finger protein, ESTs, STSs, GSSs and a putative CpG, none,TM=M„ 286
444595, AL121094, Hs 83572 hypothetical protein MGC14433, Y_phosphatase,SH2,Y_phosphatase,SH2, 285 411331, AW837178, , gb QV1 -LT0037-070300-100-d 11 LT0037 Homo sapiens cDNA, mRNA sequence, SH2,none, 285 410763, AF279145, Hs 8966, hypothetical protein FLJ21776, none.none, 285 440617, AA894880, Hs 181181, ESTs, none.none, 285 454071, AI041793, Hs 42502, ESTs, 7tm_1,none, 285
411040, AF007393, Hs 177574, protein kinase, interferon inducible double stranded RNA dependent inhibitor, repressor of (P58 represεor), HLH,TM=M„ 285 402183, , , NM 004491* Homo sapiens glucxorticoid rxeptor DNA binding fxtor 1 (GRLF1), mRNA , none,SS=M, 285 428753, AW939252, Hs 192927, hypothetical protem FLJ20251, none,TM=M„ 284 417070, Z19077, Hs 172004, titin, fn3,ιg,SGXXSG,pkιnase,TM=M„ 284 458456, AI122709, Hε 153609, ESTε, bZIP,Armadιllo seg,rrm,NTF2,none, 284
421226, AL096748, Hs 102708, DKFZP434A043 protein, Armadιllo_seg,ιπtegπn_B,PSI,TIG,TM=M,SS=M, 284 436733, BE327477, Hs 166941, ESTs, 7tm_3,oxιdored_q5_N,Presenιlιn,PWI, 284 427161, AI024595, Hs 97508, a disintegnn and metalloproteinase domain 6, ιg,TM=Y,SS=M, 284 419462, AF071076, Hs 112255, nucleopoππ 98kD, DEAD,helιcase_C,NucIeoporιn_FG,homeobox,SS=M, 283 413658, AA055369, Hs 75456, A kinase (PRKA) anchor protein 10, none.none, 283
400749, , , NM.003105* Homo sapienε εortilin-related rxeptor, L(DLR class) A repeats-containing (SORL1), mRNA ,
EGF,fn3,ldl rxept_a,ldl rxepLb,granulιn,BNR,TM=Y,SS=M, 283 447388, AW630534, Hs 76277, Homo sapiens, clone MGC 9381 , mRNA, complete eds, TB2_DP1_HVA22,TM=Y,SS=M, 283 413243, AA769266, Hs 193657, ESTs, pkιnase,zf-C4,ERM,CNH,noπe, 283 423690, AA329648, Hε 23804, ESTε, Weakly similar to PN0099 son3 protein [H sapiens], ιon_trans,IQ,none, 282
447993, AW139525, Hs"170362, ESTε, none.none, 282 423061, AI290473, Hε 44807, ESTs, ιntegπn_B,Sema,PSI,TIG,none, 282
440619, AW408586, Hs 91052, ESTs, Moderately similarto ALU5.HUMAN ALU SUBFAMILY SC SEQUENCE CONTAMINATION WARNING ENTRY [H sapienε], abhydrolase_2,none, 282 423497, U92642, Hs 129701, G protein-coupled rxeptor 45, 7tm_1,TM=Y,SS=M, 281
446126, AW085909, Hs 10177, plxkstπn homology domain interxting protein, none.none, 281 452488, N74921, Hs 184389, ESTs, noπe,TM=M„ 280 449515, AI653378, Hε 302012, ESTs, ιon_trans,TM=Y,SS=M, 279 443881, R64512, Hs 237146, hypothetical protein FLJ12752, none.none, 279 449636, AI656608, Hs 281328, ESTs, Weakly similar to T00378 KIAA0641 protein [H sapiens], pkιnase,hormoπe3,TM=Y,SS=M, 278
424348, AB020523, Hs 266258, endonuclease G-like 1, Endonuclease,TM=M,SS=M, 278 418844, M62982, Hs 1200, arxhidonate 12-lιpoxygenase, lιpoxygenase,PLAT,TM=M„ 278 442233, AW967149, Hs 28439, ESTs, Weakly similar to 138022 hypothetical protein [H sapiens] MIF.sugar.tr.none, 278 450010, AW293801, Hs 255052, ESTs, ARID,7tm_1, 278 452813, U54727, Hs 191445, ESTs, pkinase Activin.recp.noπe, 278 418177, N44967, , ESTs, pkinase.none, 278
408014, AA723782, Hs 41749, protein kinase, cGMP-dependent, type II, cNMP_bιndιng,pkιnase,SS=M, 277 448362, AA641767, Hs 21015, hypothetical protein DKFZp564L0864 similarto HIAT1, sugar_tr,TM=Y,SS=M, 277
423994, X01057, Hε 1724, interleukin 2 rxeptor, alpha sushι,TM=Y,SS=M, 277
427342, AL110150, Hs 176680, Homo sapiens mRNA, cDNA DKFZp586D0724 (from clone DKFZp586D0724), πoπe.NA.NA, 276 447574, AF162666, Hs 18895, tousled like kinase 1, pkιnase,TM=M„ 276
442681 AI809182, Hs 130907, ESTs traπsketolase,E1_dehydrog tranεkeLpyr,transketolase_C,pkιnase, 275 433637, AW024214, Hs 102307, ESTs, Na.sulph.εymp.aa permeases,TM=Y,SS=M, 275 458997, AW937420, Hs 69662, ESTs, SH3,RhoGAP,FCH,TM=M„ 275 432284, AA532807, Hs 105822, ESTs, pkinase.none, 274 406139, , , Target Exon, ig Tub,TM=Y,SS=M, 274
439518, W76326, , gb zd60d04 r1 Soares_fetal_heart_NbHH19W Homo sapiens cDNA clone 5' similar to coπtainε Alu repetitive element,, mRNA εequence, Armadιllo_εeg,none 274
428536, AI143139, Hε 2288, viεinm like 1, ethand,SS=M, 273
400211, , , NM_003899* Homo sapiens PAK-interxting exchange fxtor beta (P85SPR), mRNA VERSION NM_0038971 Gl, SH3 PH,RhoGEF,Terpene_εynth,TM=M„ 273 402129, , , Target Exon, SH2,Peptιdaεe_C9,TM=M„ 273 424238, AA337401, Hε 137635 ESTε, none,TM=M,SS=M, 273 433834, AA620742, Hs 130786, ESTs, SPX,EXS,TM=Y„ 273
409339, AB020686, Hs 54037, xtonudeotide pyrophosphatase/ptiosphodiesteraεe 4 (putative function), Sulfatase,Phosphodιest,TM=M SS=M, 273 408163 AW779842, Hs 258217, ESTs, 7tm_1,zf B_box zf-C3HC4,7tm_1,zf-B_box,zf-C3HC4, 273 422358, AL133030, Hs 115429, Homo sapienε mRNA for KIAA1666 protem, partial eds, SH3,TM=M„ 273 426409, AA594207, , gb nn29e01 ε1 NCI_CGAP_Gas1 Homo sapiens cDNA clone 3', mRNA sequence, pkιnase,Fιbnllaπn,none, 272 400645, , , Target Exon, lιg_chan,SBP_bac_3,ANF_receptor,πone, 272
443661, AA336609, Hs 10862, Homo sapiens cDNA FLJ23313 fis, clone HEP11919, adenylatekinase.none, 271 442572, AI001922, Hs 135121, hypothetical protein FLJ22415, none,HSP70, 271
409317, U20165, Hs 53250, bone morphogenetic protein receptor, type II (BMPR2), pkιπase,Actιvιπ_recp,TM=M SS=M, 271
403201, , , Target Exon, none,, 271 459357, AW848421, , gb IL3 CT0214-150200 075-B11 CT0214 Homo sapiens cDNA, mRNA sequence, ABC_tran,ABC_membrane,ιon_trans, 270 439935, S75105, Hε 8358 glutamate rxeptor, lonotropic, kainate 2, ANF_rxeptor,lιg_chan,none, 270 414924, C06267, Hε 44247, ESTε, none.none, 269 421008, BE259378, Hε 103147, hypothetical protein FLJ21347, DUF255,, 269 449951 , AA004982, Hε 120904, ESTs, DED.Calsequestπn, 269 411226, AW833022, , gb RC3-TT0005-191099-012-d04 TT0005 Homo εapienε cDNA, mRNA εequence, pkinase.none, 268
417625, U59305, Hs 44708, Ser-Thr protein kinase related to the myotonic dyεtrophy protein kinaεe, pkιnase,bZIP,G-gamma,K-box,pkιnase_C,SS=M, 268 408051, AI623351, Hs 172148, ESTs, PH.RhoGAP.none, 268 412521, AW753481, Hs 294022, hypothetical protein FLJ14950, SH2,TM=M„ 268 413922, AI535895, Hs 221024, ESTs, ιon_trans,RYDR_ITPR,MIR,UDPGT, 268 432188, AI362952, Hs 2928, solute carrier family 7 (cationic ammo acid transporter, y system), member 1 , aa _permeases,TM=Y,SS=M, 267 415516, F11411, , gb HSC2WF081 normalized infant brain cDNA Homo sapiens cDNA clone c-2wf08, mRNA sequence, lon.traπs none, 267 419749, X73608, Hs 93029, sparc/osteonxtm, cwcv and kazal like domains proteoglycan (teεtican), kazal,thyroglobulιn_1,SS=M, 266 416095, AW014327, Hε 221951 , ESTs, Weakly similar to I38022 hypothetical protein [H sapiens], ιg,zf-C3HC4,Cbl.N,Cbl_N2,Cbl_N3,none, 266 403609, , , C3001199 gι|7494834|pιr||T15308 hypothetical protein B0286 2 - Caenorhabditis elegaπs||41, 7tm_1,7tm_2,GPS,WIF,TM=Y,SS=M, 266 458213, AL047521, Hs 12210, hypothetical protein FLJ13732 similar to tensin, pkinase.none, 266
426158, NM_001982, Hs 199067, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3, Fuπn-like pkιnase,Rxep_L_domaιn,Fuπn- lιke,pkιnase,Rxep_L_domaιn,Peptιdase_M24, 266 435410, AL135067, Hs 117182, ESTs, none,pkιnase,RBD,DAG_PE-bιnd, 266
437838, AI307229, Hs 184304, ESTs, CARD,ICE_p20,ICE_p10,HIT,voltage_CLC,CBS,HCCAjsomeraεe, 266 430293, AI416988, Hs 238272, ositol 1,4,5-tnphoεphate rxeptor, type 2, ιon_tranε,RYDR_ITPR,MIR,πone, 265 433090, AI720050, , immortalization-upregulated protein, πone,SS=M, 265
432103, T15803, Hε 272458, protein phoεphataεe 3 (formerty 2B), catalytic εubunit, alpha isoform (calcineunn A alpha), Metallophos,TM=M„ 265 435852, H72303, Hs 36011 , ESTε, pkinase.none, 264 433327, AI674779, Hs 126744, ESTs, none,7tm_1, 264 438459, T49300, Hs 35304, Homo sapiens cDNA FLJ13655 fis, clone PLACE1011503, πone,FMO-lιke, 264
432251, AW972983, Hs 232165, polycythemia rubra vera 1, cell surfxe rxeptor, none,TM=M,SS=M, 263 446963, AI862668, Hs 1 6333, ESTs, OMPdxase,Pπbosyltran,pkιnase,RhoGEF,PH, 263 444821, AA053564, Hs 12040, STE20-lιke kinase, pkιnase,TM=M„ 263 436206, AK001451, , CD2-aε8oαated protein, none.none, 263 434370, AF130988, Hs 58346, xtodysplaεin 1, anhidrotic rxeptor, death,Kunιtz_BPTI,TM=Y,SS=M, 263 439039, AI656707, Hε 48713, ESTε, pkinase.none, 263 449656, AA002008, Hs 188633, ESTs, PIP5K,none, 263 429341, X73874, Hε 2393, phosphorylase kinase, alpha 1 (muscle), none,TM=M„ 262 445174, AV652850, Hs 172004, Mm, fn3,ιg,SGXXSG,none, 262 424950, AA602917, Hs 156974, ESTs, none.CDP-OH.P.transf, 262
438141, AW946871, , gb RC2-ET0022-080500-012-d02 ET0022 Homo sapienε cDNA, mRNA sequence, SH2,STAT,STAT_bιnd,STAT_prot,none, 261 434938, AW500718, Hs 8115, Homo sapiens, clone MGC 16169, mRNA, complete eds, pkmase,TBC,Rhodaπese,TM=M„ 261 409264, NM 014937, Hs 52463, KIAA0966 protein, Syja N,TM=M„ 260
458438, AI141520, Hs 151464, ESTs, Weakly similar to ALUC HUMAN "" ALU CLASS C WARNING ENTRY '" [H sapienε], pkinase.none, 260 400719, , , NM.004055* Homo sapienε calpam 5 (CAPN5), mRNA VERSION NM 0043352 Gl, C2,Peptιdase_C2,Calpaιn 1II,TM=M„ 260 427318, AF186081, Hs 175783, zinc transporter, Zιp,TM=Y,SS=M, 259 426086, T94907, Hs 188572, ESTs, PH,Ets,CH,spxtπn,Ca_channel_B,none, 259
430105, X70297, Hε 2540, cholinergic rxeptor, nicotinic, alpha polypeptide 7, Neur_chan_LBD,Neur_chaπ_memb,pkιnase,TM=Y,SS=M, 258 411495, AP000693, Hs 70359, KIAA0136 protein, HATPase_c,bZIP,TM=M„ 2 58 438167, R28363, Hs 24286, ESTs, none,TM=Y,SS=M, 258
418749, N75147, Hs 22488, ESTε, noπe,zf-C2H2,KRAB,pkιnase, 258 454289, AL137554, Hs 49927, protein kinase NYD SP15, dCMP_cyt_deam TM=M„ 258 443605, H06865, Hs 134131, ESTs, efhand.ionjrans.none, 257 429429, AA829725, Hs 334437, hypothetical protein MGC4248, none,transmembrane4, 257 403088, , , NM_003319* Homo εapienε titin (TTN), mRNA mRNA , fn3,ιg,SGXXSG,TM=M„ 2 57
409190, AU076536, Hs 50984, sarcoma amplified sequence, transmembrane4,TM=Y,SS=M, 257 426696, AW363332, Hs 171844, Homo sapienε cDNA FLJ22296 fis, clone HRC04468, ig TM=Y,SS=M, 256 403328, , , Target Exon, Glyco_hydro_35,TM=M„ 256 426167, AF039023 Hs 167496, RAN binding protein 6, Armadιllo_εeg,HEAT_PBS„ 256 428695, AI355647 Hs 189999, puπnergic rxeptor (family A group 5), 7tm_1,TM=Y,SS=M, 254 419285, D31887, Hs 89868, KIAA0062 protein, Zιp,TM=Y,SS=M, 254
415740, N80486, Hs 39911, Homo sapiens mRNA for FLJ00089 protein, partial eds, CBM_21,TM=M„ 253 403305, NM.006825, , transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment pkιnase,TM=Y,SS=M, 253
443804, AL135352, Hε 255883, ESTε, Weakly similar to I38022 hypothetical protein [H sapiens] Peptιdase_M18,Peptιdaεe_M18,Y_phosphatase, 253 450425, H06607, Hs 6099, ESTs, E1-E2_ATPase,Catιoπ_ATPase_C Catιon_ATPase_N,Hydrolase,noπe, 251
401702, , , NM_001171* Homo εapienε ATP-binding cassette, sub family C (CFTR/MRP), member 6 (ABCC6), mRNA , ABC_tran,ABC_membrane,TM=Y SS=M, 250 439463, W69304, , gb zd46f01 r1 Soares_fetal_heart_NbHH19W Homo sapiens cDNA clone 5', mRNA sequence fn3,Y_phosphatase,πone, 2 50 425975, AB011082, Hs 165559, organic cationic transporter-like 4, sugar_tr,TM=Y„ 250
443259, AW090601, Hs 69171, protein kinase C-like 2, pkιnase,pkιnaεe_C,HR1,none, 250 400777, , , NM 007325* Homo εapienε glutamate receptor, lonotrophic, AMPA 3 (GRIA3), transcript vaπant flip, mRNA , lιg_chan,SBP_bao_3 ANF_receptor,TM=M,SS=Y,
249 426044, AA502490, Hs 170290, ESTs, none.none, 248 454564, AW807573, , gb MR1-ST0088-021299 004-g01 ST0088 Homo εapienε cDNA, mRNA sequence, pkinase none 248
415938, BE383507, Hε 78921, A kinase (PRKA) anchor protein 1, KH-domaιn,TUDOR,TM=M,SS=M, 247
426481, AW963941, , gb EST376014 MAGE resequences, MAGH Homo sapiens cDNA, mRNA sequence, Y_phosphatase,Band_41,DSPc,none, 246 426005, AA377499, , gb EST90341 Synovial sarcoma Homo sapiens cDNA 5' end, mRNA sequence, tubulm,FKBP,C0X6B,7tm_1 ,tubulιπ_C,SS=M 246 424879, AA348013, Hε 273385, ESTs, arf,G-alpha,πone, 246 415156, X84908, Hε 78060, phoεphorylaεe kmase, beta, none,TM=M„ 246
416508, R39769, , ESTs, Moderately simitar to ALU8.HUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens],
SH3,PDZ,Guanylate_kιn,ZU5,none, 246 408087, AW150645, , gb xg54f07 x1 NCI_CGAP.Ut4 Homo sapiens cDNA clone 3', mRNA sequence, XYPPX,ABC_membrane,ABC_tran, 246 433434, AA588429, , gb no22b03 ε1 NCI CGAP Pr22 Homo εapiens cDNA clone 3', mRNA εequence, pkιnase,DNA_mιs_repaιr,HATPase c, 245 446768, AV660305, Hs 110286, ESTε, ICE_p20,DED,ICE_p10,ICE_p20,DED, 245
437158, AW090198, , KIAA1150 protein, none,NA,NA, 245 430177, AW969233, Hε 302746, MSTP028 protein, KJetra.none, 245
422270, AF114494, Hε 114062, protein tyroεine phosphatase-like (proline instead of catalytic argmme), member a πone,TM=Y„ 245 430680, AW138724, Hs 168974, ESTs, Highly similar to ALU7.HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens], Y_phosphatase,Adaptιn_N,Y_phosphatase, 244
446569, AW248031, Hs 155839 hypothetical protein MGC12934, adh_zιnc,PGK,Semιaidhyde_dh,SS=M, 244 411902, AW875344, , gb RC1-PT0009-220300 013 f06 PT0009 Homo sapienε cDNA, mRNA sequence, none.pkinase ank, 243 430057, AW450303, Hs 2534, bone morphogeπetic protein rxeptor, type IA (BMPR1 A) (ALK-3), Actιvιn_rxp,pkιnase TM=Y,SS=M, 243 446338, AI289121, Hs 206978, ESTs, none,SH3, 242 426221, AB007881, Hs 110613, KIAA0421 protein, none,Rιboεomal_S8, 242
446796, AI652497, Hs 110103, RNA polymerase I transcription fxtor RRN3, none.none, 241 428360, H10291, Hs 30974, ESTε, pkmaεe.PBD.none, 240
428379, X06026, Hs 2259, CD3G antigen, gamma polypeptide (TιT3 complex), ITAM,TM=Y,SS=M, 240 432488, AA551010, Hs 216640, ESTs, Na.sulph.εy p.none, 240 407235, D20569, Hε 169407, SAC2 (εuppreεεor of xtin mutationε 2, yeast, homolog) like, none,Rιbosomal_S13,Galactosyl_T,Zιp,adh_short,zf-C3HC4, 240
448595, AB014544, Hs 21572, KIAA0644 gene product, LRR,LRRCT,TM=Y,SS=M, 240
428283, AI439096, Hs 323079, Homo sapiens mRNA, cDNA DKFZp564P116 (from clone DKFZp564P116), Y_phosphatase,fn3,ιg,none, 239 432460, H12912, Hs 274691, adenylate kinase 3, adenylatekiπase.none, 238 429549, AI333013, Hs 250505, retinoic xid rxeptor, alpha, none,zf-C3HC4,BRCT,lιg_chan, 238 429303, AW137635 Hs 44238, ESTs, Weakly similar to S65657 alpha-1 C-adrenergic rxeptor splice form 2 [H sapienε] Phoεphodiest Somatomedin.B.Endonuclease none, 236
417473, M55268, Hs 82201, caεein kinase 2, alpha prime polypeptide, pkιnase,ABC1,TM=M„ 235 453186, AK001708, Hs 32271, hypothetical protein FLJ10846, TK,DUF300,TM=Y,SS=M, 233 447276, AL049795, Hs 17987, hypothetical protein MGC1203, none,TM=M„ 233 445310, AI242490, Hs 153290, Homo sapiens cDNA FU14318 fis, clone PLACE3000402, none.pkinase, 231 432942, AF083955, Hs 279852, G protein-coupled rxeptor, 7tm_1 ,globιn,TM=Y,SS=M, 230
434693, AW976001, Hs 337603, ESTs, none.none, 226
452034, F12234, Hs 75893, aπkyπn 3, node of Ranvier (ankyπn G), ZU5,death,none, 225
423732, AF058056, Hs 132183, solute earner family 16 (monxarboxylic xid transporterε), member 7, sugar_tr;TM=Y,SS=M, 225
404956, , , C1003210* gι|6912582|ref|NP_036524 1| peflin [Homo εapienε] gι|6009487|dbj|BAA84922 1| (AB, none,PI3_PI4_kιπase,PI3K_C2,PI3K_rbd,PX,PI3Ka,C2, 224 452183, NM.006594, Hs 28298, adaptor-related protein complex 4, beta 1 subunit, Adaptιn_N,Y_phosphatase, 223
420529, D25259, Hs 319844, ESTs, Moderately similar to I54374 gene NF2 protein [H sapieπε], pkιnaεe,DAG_PE-bιnd,RBD,raε,DC1 ,GFP,TM=M„ 221 408808, BE074219, Hs 17230, hypothetical protein FLJ22087, Armadιllo.seg,TM=M,SS=M, 221 451932, AA360954, Hs 27268, Homo sapiens cDNA FU21933 fis, clone HEP04337, SH3,PH,RhoGEF,TM=M„ 221 432008, AW296791, Hs 193170, hypothetical protein FLJ21687, LIM,Synaptophysιn,ιon_trans,KOW, 220 455840, BE145897, , gb MRO-HT0208-221299-204-b07 HT0208 Homo sapiens cDNA, mRNA sequence, PI3_PI4_kιnase,PI3Ka,PI3_PI4_kιnase,PI3Ka, 2 19
429238, NM.002849, Hs 198288, protein tyrosine phosphatase, rxeptor type, R, Y_phosphataεe,TM=Y,SS=M, 2 19
430975, AA490055, , gb ab05b09 s1 Stratagene fetal retina 937202 Homo sapienε cDNA clone 3', mRNA εequence, adenylatekιnase,Thymιdylate_kιn,TM=M„ 2 17 407174, T79938, Hs 77062, leukxyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5, ig.none, 216 450921, AA098790, Hs 146245, ESTs, Moderately similar to T17242 hypothetical protein DKFZp586B1417 1 [H sapiens], none.NA.NA, 2 15 427209, H06509, Hs 92423, KIAA1566 protein, pkιπase,TM=M„ 214
401917, AL050149, , RAN binding protein 3, Orexm,SH2,STAT,STAT_bmd,STAT_prot,ιon_trans,PAC,PAS,πoπe, 2 12 426359, AA376409, Hs 10862, Homo sapiens cDNA FLJ23313 fis, clone HEP11919, adenylatekinase.none, 207
439520, W76548, Hε 336621 , ESTε, Moderately similar to ALU5 HUMAN ALU SUBFAMILY SC SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens], lon.trans.noπe, 206 410439, R35943, Hs 63758, transferπn rxeptor 2, PA,TM=Y„ 205
448696, A1564769, Hε 173070, EST, Weakly similar to ZN42_HUMAN ZINC FINGER PROTEIN 42 (MYELOID ZINC FINGER 1) (MZF-1) [H sapiens] none zf-C2H2, 204 449543, AF070632, Hs 23729, Homo sapiens clone 24405 mRNA εequence, K_tetra,ιon_trans,none, 204 453496, AA442103, Hs 33084, solute earner family 2 (facilitated glucose/fructose transporter), member 5, sugar_tπTM=Y,SS=M, 202 443952, AI149106, Hε 143530, ESTε, pkinase.none, 202 437589, AA761322, Hs 269662, ESTs, SH2,SH3,C2,PH,RasGAP,none, 202
422637, AA399024, Hs 118836, myoglobin, globιn,TM=M„ 201
450253, AL133047, Hs 24715, Homo sapiens mRNA, cDNA DKFZp434D0215 (from clone DKFZp434D0215), partial eds, SH3,TM=M„ 1 97 401984, , , C17000146* gι|2143629|pιr||A57156 Ca2+/calmodulιn-dependeπt protein kmase (EC 27 1 123) I, pkinase,, 1 96 453464, AI884911, Hs 32989, receptor (calcitonin) activity modifying protein 1 , none,TM=Y„ 1 95 417733, AL048678, Hs 82503, H sapiens mRNA for 3'UTR of unknown protein, none.NA.NA, 1 94
411450, H49619, Hs 127301, ESTε, pkinase.none, 1 82
406303, , , C16000922 gι|7499103|pιr||T20903 hypothetical protein F14F43b - Caenorhabditis eleganε gi, ABC_tran,GTP_EFTU,PRK ABC_membrane,TM=Y„ 1 80 425009, X58288, Hε 154151, protein tyroεine phosphatase, receptor type, M, fn3,ιg,Y_phosphatase,MAM,TM=Y,SS=M, 1 74 425280, U31519, Hs 1872, phosphoenolpyruvate carboxykmase 1 (soluble), PEPCK,TM=M„ 1 65
425958, AW163271, Hs 301839, intracellular antigen detected by monoclonal antibody Kι-1, intracellular hyaluronan-bmdmg protein, Y_phosphatase,DSPc,TM=M„ 1 63
432563, NM.013261, Hs 198468, peroxisome proliferative activated rxeptor, gamma, coxtivator 1 , rrm,TM=M„ 1 51
TABLE 49B
Pkey Unique Eos probeεet identifier number
CAT number Gene cluster number Accesεion Genbank acceεsion numbers
Pkey CAT Number Accession 438091 22448.1 AK054860 AV652198 AV652192 AV652138AV652127 AV652194 BE935919 AV652017AV651995 AV651548AV646063AV651985 AV646184 AV646179 AW880409 AA345002 BF155189 BE068931 X56197 AL603014 AW953629 BM263546 BE550772 AA701084 AI681352 AA358689 AW938841 BF438147 W05391 H75313 BF326185 AV646335 AV651589 AV646340 AV651992 AV646384 AV646364 AV687497 BF155183 AV646370 AW797876 AI906821 X56196 BE833835 AA628440 BE833808 BF224205 AA709126 BE673807 AI923886 AA947932 AI276125 AI185720 AW510698 AA987230 BE467708 AW898628 AW898544 AI146984 AW043642 AI288245 AI186932 AI635262 AI139455 AI298739 AI813854 AI024768 BE699445 BE699444 AI707807 D52654 AI214518 AI004723 AI698085 AW087420 AI565133 AA845571 AW898622 BF110144 AW513280 AI061126 BF362770 AI268939 AI435818 BF475318 AI024767 BE174213 AA757598 AA513019 AA902959 AI860794 AI334784 BF108411 BM310532 AW513771 AI951391 AI337671 BF095606 BF095601 BF095468 AW890091 BF095753 AW243400 AW898607 AW898616 BF362762 AI922204 AW898625 BE699468 BE174196 AW102923 D52715 BE699456 D52477 D55017 BF955933 BG623563 AV646254 AA463522 BI003244 AI299190 W40186 BE174210 BF939091 BF434180 AW579001 T55662 H01811 T52522 BF945037 BF955938 D54679 D53933 R67100 BG925552 BF999056 R83430 Z29922 T85791 W03942 H63289 AI091537 BF086583 AA345570 H48870 H80720 T83523 BI039626 BI037700 R00353 BF155184 N98343 N79072 H01812 T55581
411089 5597.6 BI009308 BI009893 BF922023 BF922909 BF922913 BF922096 BF957733 BE701791 AA456454 AA579876 BF933710 AA091294 BI007291 AW905577 AW975593 AA713730 AW836781 AA666384 AA551106 BF594606 AI082382 AI955808 AI679895 AI679386 BF435555 AA586369 AA551351 AA595822 AA565188 BF808855 AA584921 N86077 AA601031 AA633188 AA514764 AA454562 AA551297 AA936109 BI009389 AW897806 BE815442 BF739374 BI009310 BF925422 BF933709 BF922034 BF925465 BI009680
439285 22495.1 AF086101 AL133916 AW955684 AW950828 AI346341 AI867454 BM263376 BF432231 AI421279 AI655270 AW014882 BF439949 AA775552 N62351 AA626243 N59253 AI341407 AA456968 AA457077 AI358918 AA364013 N79113 N54784 BE175639 N76721 AV727392 Z45529 Z44343 F05908 F05403 F05398 438089 22448.4 BM475665 BE644917 AW770789 AW952971 N64863 BM263259 AI224545 AI184866 N69114 AW518902 AI440169 AA809472 AV654440 AA281642 AU185230 AW337382 AI872923 AI537113 N73882 T83378 H63731 BF671764 AW897824 AI811204 AA344646 BE009112 BG899664 H91240 R60548 N41701 432407 MH1429.12 BG036675 BF772005 BF771866 BG960386 BG960381 NM.005712 AF110315 BE074534 BE182776 BE158000 BE157999 BE714315 AW818104 AW847519AA099426 AW817981 AW856396 BG961122 AA224498 AA308542 AW821833 BF902155AI732411 BG778834 BG283641 BE748279 BE748870 BG319540 BE748864 BF739224 BG986155 AK057283 BI861466 AA663341 AA457591 BG949294 AW392886 AA071122 AA227849 AA584918 BG959570 BF773486 AL041698 BF959013 R87170 C16859 BF770411 BF771298 A1075321 L13823 AA216700 BF771864 AW861859 BE537068 C18935 AA155719 BF771172 BF769107 BF804964 AW818172 AW818143 AW392930 AW817057 AW858044 BF746211 AA179928 AW861687 AW821826 BI055726 BF242643 AA207189 BF770412 BF771157 BG430030 AA055592
414883 8371.2 AF274943 BG494894 AI719075 AA908783 AI935150 AI422691 AA910644 AA583187 BM272167 AI828996 AA527373 AW972459 AI831360 AA772418 AI033892 AA100926 AU154749 AI459432 AI423513 AI094597 AA740817 AI991988 AI090262 AI312104 BI256707 AA459522 AA416871 AI075239 AI339996 AA701623 AI139549 AI336880 AA633648 AI989380 AI362835 AA399239 AI146955 BF514270 N92892 AI348243 AI278887 AA459292 AI494230 BF507531 AI492600 AA962596 AW613002 AA293140 AA235549 BF108854 AA954344 N49682 AI457100 AW589407 AW300758 BE220715 BE220698 BE569091 BM009647 BF900351 AI537692 AI203723 AI857576 AA584410 AW371667 BM172363
451320 12225.2 AK057826 AI631982 AA224195 AI701458 AA890570 AW966562 AW071907 AI671352 AI375892 T03517 A1124088 R88265 AI084316 BF223720 AI354686 T33652 AW205836 BE931115 AI720211 T03490 BF084055 AI372637 T15415 BG054890 AA630384 F26326 Al 140719 AA443303 T33230 T33623 T33511 T33785 AW118072 W20198 AI657180 T15734 AI419606 N90552 AA224388 T15909 T03515 D55612 W27899 400205 2538.1 NM.006265 D38551 X98294 BM477931 BM461566 AU123557 AU133303 AU134649 AW500421 BM172439 AW500587 AW503665 AW504355 AW503640 BM152454AW505260 AI815984AW504075 AW500716AL597310 BC001229 BM474371 AA984202AU135205 BE090841 AW163750 BF747730 BF898637 AI206506 AV660870 AV692110 AW386830 AV656831 N84710 AW993470 BF086802 BF758454 BG960772 BF757769 BI870853 BE018627 C75436 AW148744 BF757753 BG622067 BE909924 AA708208 BG530266 BF968015 AW992930 BF888862 BG536628 AA143164 AW748953 BG498922 BF885190 BF889005 BF754781 BF800003 BM476529 AI627668 AW028126 AL046011 BF590668 AI017447 AA579936 AI367597 AA699622 BE280597 AI124620 AI082548 AW274985 AA677870 AI056767 BE551689 AA287642 H94499 AI752427 AI652365 AW002374 AW062651 AA360834 N68822 AU135442 AU125960 Z78334 BE545813 AI092115 BF312771 BF242859 BG533616 BG533761 BG164745 BG492433 BM473183 AA172043AA172069 AU157092AU151353 AU155318 BE302211 AI375022AA085641 AU157923 H88858 AA132730 AA115113 AA909781 AI475256 AA424206 AW572383 AW084296 AI184820 AI469178 AA782432 H92184 AA340562 BF195818 AA852821 AW576342 AA827107 AA173317 AW190014 AI918514 AA729372 AA729718 AI055958 AA331424 BE328601 AA515690 BI018896 AW628277 AA748368 AA626222 BG492636 AW380620 BF800058 AW370956 AA290909 R25857 BG952995 BF801437 AA172077 AU155890 AU149783 AI720904 AA902936 AA865727 AI470830 AV740677 AA142982 AA482485 AU145485 AW576399 AU156042 R63448 BF246427 BE928472 D25910 BF758439 BF968785 BE565238 AA355981 AI905607 BG291148 BG533096 BG532888 BF030886 BG613756 BE928471 BG574501 AA187596 AA361196 T95557 BG531446 BG527242 BG527513 BG611106 AA085995 BF847252 BG024608 BE540261 BG531236 AL579993 BG108733 BG483503 BG571032 BG492505
400210 133.1 BC014030 NM.Q04068 BC004996 AK057883 D63475 BM468205 BG386792 BG750447 BG575842 BG479084 BG741027 AU118129 BE901043 AU141281 BG825395 BG338276 BE396231 AU121493 AU131489 BF341132 BG335659 BI769251 AU142779 AU124483 BG480828 AU121353 BG702326 AU137866 BG759046 BI460601 BE887290 BG750415 BF127710 BG757819 BI160266 AU122086 BG824046 BG744180 BE884943 BM006610 BG702599 BI870749 BF307033 BI334771 BG480606 AU142599 AU141336 BM018563 BI335565 AU138308 BE391241 BG774488 BE278025 BG717959 BG706920 BE312567 AU138300 BE303034 BE303016 AU139252 BE336797 BG470940 BE336735 BF305197 AU134288 AU139907 BE261245 BE208718 BG761912 BF212890 AW732692 BM011258 AW247629 AU136696 BF530078 BF204146 AL048752 BG328927 BE388385 BE260122 AU138789 BE253465 BF733914 AW249415 AW239535 BE311791 BE256236 BF529742 BG770465 AW245777 AW245813 BE296677 BE266852 BE168115 BE396596 BE280057 BE168229 AI750820 AU134137 BF792191 AI272215 AI907348 AW238875 BF805152 BF568397 BE712727 BE081443 BE001805 BF724536 BF744705 AW247385 BE796369 AU133759 AV705142 BE794402 BM465821 BG281284 AW384831 BM450689 AU134125 BE311650 BF356318 BM462831 BG420555 BE749127 AU134590 BM019438 BC013796 BG761223 BG122058 BE872076 BG748496 BG821374 BE619159 BG423244 AU137110 AU127210 BE270081 AA496860 AA351380 AA356303 AU099781 AA355912 AA371411 AA325535 U36188 AL569574 AL577204 AL525543 AL567342 AL567334 AL567122 AL536527 AL567098 BG681585 BG824951 BI870652 BI225855 AW393878 BG750632 BI223803 BE877552 BE270473 BE389392 BE779021 BM017845 BI117816 BE396513 BM049006 AW393945 BE786941 BE267724 BE562981 BE314236 BF744102 BM019781 BF806063 BF828673 BF829181 BI008788 BF829180 BF829175 BF433802 BE909928 BF839784 AW578564 BF943095 AW328030 AA448596 AW882688 AA909846 BF924341 AW361460 AA425174 BE940557 BF761585 BF931276 BF934886 W68597 BF933977 BI035906 BE836064 BF837576 BI018368 AA205908 H54612 R88902 BE812330 BE932300 BF924562 AW805376 BE769859 R87381 AA371901 BE838855 AA326381 W56191 AA341231 AA464093 AL575977 AL518650 AL547393 BG338327 AL517563 AL536921 BG207096 BG207589 BG199290 BG220159 BG744842 BG104730 AA555035 AA618009 AA861062 AA610582 AW245418 AI040983 AA521380 AW245455 AU147292 AU155236 BE620286 AW250767 BF888236 BE620819 AU154343 AU150827 AU148334 AW069495 AA701091 AU155225 AW250019 AA666235 AU147764 AA449739 BF907598 AW043731 AU144390 AI924565 BE300631 AW874021 BE208088 BF732773 BF594057 A1159873 AU143930 N24100 AI052499 AI989370 AI366151 AI139248 AU144776 AA838250 AI095433 AI269227 BF811358 AU151352 AA477554 AH 31290 AI049797 AU157349 AA620559 AA581533 AI338299 AA402755 AI050079 AU157614 AI280691 AA706590 BE206615 AA861056 AU153214 AU155712 AW069554 AI081124 AU155846 AI081123 AA719876 AI754976 AI027763 AA723095 BI518782 AW050706 F37521 R79062 AA565530 H39826 AA404670 AU158884 AI139682 AA513633 AI283202 AA651856 AI623515 AA427413 AW248474 BF841432 BM453246 A1302390 AA808269 AI249357 AA132775 AA716732 AA479832 AI198296 AI208674 AI088433 F36977 AA496899 AW615762 AA602541 AA341161 D58785 T15399 AI286077 W69152 F28418 AI272156 AA338034 AA568455 BE206121 AI080033 AI699680 AA861255 AI953465 AI613240 AL581773 AL531577 BF526361 AA657809 AW152670 BE621523 AW078705 AW673719 AA102613 AA195604 R72209 AA402208 AA404305 N24999 AI963535 D54741 BI461415 BM475959 BI260926 BI116213 BE280120 BE940258 BE280044 AI905744 BG001474 BE937718 BF799283 BI091621 BG421006 BG289235 BF736825 BI253429 BG170064 R72512 T92815 BF931257 BM455183 BG033362 BG574220 N31395 BF739185 AA371995 BE879011 BI198754 BF378989 T12266 BM019421 BI194570 BF378992 AW996595 BI858649 W94605 W61345 AA122384 AA171923T92736 AA761504 AI819039 AI439358 AL517777 AL565919 AA622001 AA642695 AA704144 AA081465 AA070621 AA375562 AA700011 AA926863 W37310 AL566236 BF677809 BG760021 AW361433 BE828605 BE268449 BF805977 BG292452 BF981071 BF217108 BF928698 R33993 AW882841 A1857453 AW078733 A1433035 AI018103 R90927 AA804720 AA551734 R33835 H19741 R78754 BF930494 BG109583 AA631926 BE834008 BG996533 433470 6624 1 X75684 AL573167 AI445461 AI453743 AI983655 AI564644 AA977180 AI694111 AI591358 AW071625 AI678712 AI720939 AI927769 BE439796
AI963432 AA292956 AW192593 AI865838 AI696905 AI424384 Al 161312 AI911921 AI597801 BI494959 AI240988 AI492554 AW262737 BE044033 AW008570 AW629505 BI494958 AA088439 AA706057 BF222820 BF593608 BE501957 AA524526 BE044134 AW572531 AW015724 BE349186 AA043217 BE219784 AI799814 AA129575 AI671727 A1470033 BE646195 AW779725 AA903050 AA147228 AA404570 AI075878 W38161 AI972739 AW673152 AA723200 C06123 BF057147 AA627686 AA157944 AI990245 AA662517 T32487 AI800106 AI333170 AI859160 W45410 AI990827 AW275048 AA182640 AA478328 AI298935 AW085158 AW471421 AW103470 AW300456 AW191997 AI823466 AA962397 AA136658 AI251817 AW339104 AA724739 AA411100 AA191349 AA757735 AA037696 AI769516 AW772283 AA010631 AI692846 AI061065 H80983 R79933 AI950693 AI245632 AI349390 AA148284 AI798502 AA487893 AI621320 AW194272 C06365 AA953883 BE858936 AI918523 AI872628 AI927217 AI453453 AH 89366 AW338678 AI261359 A1500576 BF477735 AI032569 AI972899 AI985583 Z28771 AI363829 AI693030 AA603586 BE773488 AW339301 BE773489 BE773462 BE773495 AI650338 BE773499 AI745717 BE811475 BE811470 BE811464 BE811418 BE811415 BE811400 BE811398 BE811388 BE811352 BE773501 BE773494 BE773486 BE773474 BE773473 BE773470 BE773461 BE811350 BE811337 BF593847 BG055071 AW675302 BF003068 AA719173 BE811348 AI582462 AI686240 BE773500 AI244845 AI565439 AI918453 AI472527 AI446740 AA035576 AA191414 AW674145 C05782 AI589264 D57558 AI468237 AI432033 AA989662 R21752 BF002457 AA988297 AL574095 AL576200 AL571074 AL574525 AL578810 BG498381 AI928364 BE879732 AA479834 AA479712 C17732 BM091258 BF843901 AW820230 C17476 BE327120 AA129574 AA136645 BF843900 AW806193 AA502832 AA649494 AL568520 AL547960 BE706937 BE811360 BE773498 BE811401 BE773484 BE811437 BE811380 BE811399 BF997171 BF757734 BE926037 AI377596 C06111 AW088968 BE811404 BE811472 AI865912 AI925607 AI871950 AI093510 BE905927 BE811435 AA191387 AW772000 BE811453 BE614379 BF844522 BI044896 AI744233 AW984527 C17504 BF843883 AI248307 BE773483 AI567995 W60075 BF941183 AI738844 BE811458 BE773481 AI262930 AA948565 BE706942 BE156360 T65026 AW242958 AW197954 BE905184 AA722206 AI344943 AI348877 AI334860 BE621857 BE156280 AA454099 AA037722 BF843897 AW806183 AA043216 BG482896 AA182734 AA877242 AW372926 H27252 R38114 BF851858 BE156214 AA190427 T91762 AA035067 AA837326 T10930 BF906587 BI755027 BG506731 BC008442 BC010166 AL550134 AL553096 AL548700 AL550751 AL547978 AL545286 AL540643 AU118627 AL601379 BI259821 BG741786 BI868522 AU135866 BI552770 BI259210 BI256520 BI255569 BG485098 BI258228 BG498501 BM044512 AU133984 AL556586 BE745111 BI222633 AU133917 BG288151 BI260715 BI550550 BG500773 BI551761 BG707601 BI818593 BF691383 BG721129 BG541578 BE906666 BG751098 BI224135 BG400746 BG478065 BE790436 AW080238 AU137549 BG429896 BE392486 AW961686 BG721056 BE908365 BE546656 BG541235 AW583735 BG528290 BI260895 AW651691 BM048974 BM043805 BG142185 AA315188 AI446615 C06300 BG497644 AA088544 AI815987 BG528631 BE619182 AW239185 AW062910 AW062902 AA347236 F11933 AA488005 AA301631 AA376800 D56120 AA343532 AA308636 F00242 AA376086 AA316968 AA343799 BI870221 BE910282 BG538748 AW960564 AV732879 D16854 AA192519 BF922148 AA216013 BG624091 BE544387 BG507008 AW176446 BF790033 BE088925 BE088854 AA921353 R21800 AA011222 T97525
430563 6238 BC015334 AA805670 AW014686 N66615 BG029745 AA481269 H91728 454042 302541 AJ420458 AI018523 AA708686 BF949633 AL119553 BF945960 AI081305 AA041432 AI921013 AI684910 AI654847 AW874199 AI206120 AW241428 R43035 T66767 AW103715 W28478 BF953052 H45926 BF807568 AW903943 BE170143 BI040435 BF931989 BI600000 AV722350 W27787 H45331 BI549761 R53955 BI549855 BG991583 BI491075 AW020049 AW129293 H45263 AA410309 AA340613 R42410 AA707199 AI431587 BE858579 AW292267 AI421678 AA041195 BE466753 AI243913 AI358894 AW137298 AI366468 N64350 AA779107 AW025969 R49056 AA347011 R55722 AW771106 F04969 Z38381 F01659 H17396 BI493714 AI880103 AW771447 AI202561 AA788851 AI494436 BF856114 H22570
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418869 12789 14 AA229762 AA230035
400261 23110 1 BC006097 X03066 NM.002120 M26040 AW469119 AW46S127 AI299772 AW518149 AI144456 AW628070 AI629032 AI358810 AI880433 AI440472
AI357070 AI865365 AW014799 AI767973 AW518041 AA909398 AW768606 422940 58443.1 BC012771 BG397153 BF366196 AA337277 AA319285 AW843252 410032 1490765.1 BE065985 BE066083 BE066008 BE066093 BE065944 400263 18977.1 Z11692X51466 NM.001961 M19997 BI224253 BG830478 AU122147 AU123437 BG113591 BG752624 BE886804 BI868669 BG337216 AW629935 BM016525 AI560409 AL562866 AI909178 BF849556 AA371735 BF038841 BF727115 BC006547 BG757526 AL555664 BI261304 BG770095 BI033486 BI517580 BG876486 BI011828 AI313235 BG831724 BF869862 BG998348 BI011834 BF888337 BF898627 BF092380 AW803215 F01241 BF805719 BG876487 AW498536 BF988866 BG998849 AA248724 BG829202 BG756456 BG032392 BI859287 BM016990 BG332369 BE933685 BE166758 BM452445 AI937808 AW026128 N23684 AW006041 AI337621 F33111 BF344301 BG105450 BG387343 BF569547 BF154671 BM007368 BF569385 BE772007 BI199487 BF761700 BI261519 BF944452 BF898506 AI038390 BM044934 AW381142 BG743618 BE769206 BE893973 BI015047 BF886479 BF761350 BE769769 BG766117 BF847365 BE397834 AW371121 BF089125 BE082996 BF183193 BG180964 BF089940 BI000274 BG255503 BG674499 BG774174 BI015084
413227 2550186 BE072622 M79082 426966 349.1 NM.025237 AF326739 AW771508 AI498457 AI493134 AI383985 AI498691 BF431247 AI580267 D79813 AF331844 AA393939 AI783624 AA969408 AI768408 AA393768
417886 10313341 AA210987 D57294 AA214584 AA207006 D56572 452098 161393.1 BG028348 BF772844 H83066 AW817969 H90985 BF755039 AI858183 452203 26301 BC014081 NM_000593 X57522 L21208 L21207 L21206 L21205 L21204 AL561404 AL546423 AL560492 AL556882 AL541576 AL550654 BI823519 BI770023 AL554969 BI489906 AI304693 AW295947 BM146642 X57521 BG820143 BE898390 F06770 F12630 BM423610 AL561518 BM009470 BG742981 AA279685 AA847441 AA313737 BF172639 BF897216 BF914190 BF903647 S70277 AI569694 AW073296 AI361433 AA564644 AA487429 BE858232 AA838610 AI539114 AI719375 AI829129 BG057675 AI423422 AU158860 BE300655 AW170777 AA586956 AL571889 AL556850 AL576404 AL582800 BI256544 BF342301 BG875994 AA054458 AA353161 AI940434 BE816522 AL577636 AI479650 AW150377 AU154395 AW951271 AI032220 AI819778 AI346733 AW771150 AW512525 AI249904 AA279809 AI352549 AW512517 BG056280 AA521222 BE271141 AL581932AL541575 BI819184 AV660190 AL556475 A1620020 AW089888A 079179 Z21518 AA687601 F04651 AI783961 T57198 AI433367 T78652 AL554968 AA365648 AL582619 BE874601 BF804669 AL574458 BM145502 AI266514 AI538823 AI475626 AA948210 AA884054 AA487637 AA031844 AA535221 AW794256 AW361447 BE788505 AI682892 AA830989 AA862356 AA653084 BM009154 AA135727 H05927 H23433 R42244 N79997 AW366665 AW366601 AA678742 AL556474 AA135770 BE774050 BF914200 H88457 AA627746 BI560216 BI753586 439096 12419971 AW978432 AA830185 N67023 R80000 425505 1228213.1 AL036458 AA358606 AW962990 400208 16640.1 X78817 NM 001666 D50921 AW002308 AW575456 BF507511 AW467767 AI910663 BF905778 BG251264 AL562106 AI890538AW769258 AI590391 AI913055 AW083235 AI078474 AI925022 AW504628 AW129725 BE466589 AW002786 AW591760 AI968816 AW006268 AW593787 BG236814 AW769893 AW407608 AW075982 AI248207 AI762509 AI812070 AI249937 AW083561 AW080697 BF663046 BG745612 BG979546 AW793245 BI014177 AL519126 BE675314 AW806520 BI870778 BF879549 BE714919 BF847786 BG684161 AV695278 BG491029 BE793244 BE830893 BE798121 R09703 BI013066
422667 224778.1 AI758223 AW469334 BF940841 AW080348 AI270363 AI055892 BE464168 BF431797 BE350144 BF448739 A1693409 BF432999 D62848 AA398070 AI383375 AW611490
407305 2466680.1 AA715338 AA715284 AA715344 443068 18695.17 AV752763 AI032142 N30308 N22181 H95390 AW675632
433075 78.6 X98248 NM.002959 AU127082 AU143346 BE327147 AI168442 AA426361 BF056336 AA418378 AI470560 AI365213 BI032745 BI032986 AA969895 AA233278 AW291971 AA418326 AI198417 AI337018 BI032747 AA888000 AU099083 AU129681 AL036861 AA418275 BF887436 BF767448 AA232975 BI094065 BI859449 AL079651 BF877391 AW902319 BF878798 BG281450 AA418268 BG770672 BE890328 BI520437 BE387505 AW375004 BI020046 BI033747 BF800905 BF869732 N99710 BF905459 BE715637 BE746496 BF918537 BF751392 BF751390 BF369123 BG949840 AA984366 H85743 AW593418 AI990196 T92267 AA018359 H38111 BM050097 BF692315 AW805907 AI547305 AA631091 BF845219 BG949806 T92310 BE277220
400252 2656 2 U44839 NM_004651 BC000350 BI458316 AU117940 BG759024 BG749694 BE799505 BG831537AI816335AA325352AL547005 AW157038 AI859331 AI816186 AU150786 AL043549 AW162880 AU159233 AI143169 T03478 BE727648 AA764725 BE206603 AI369814 AI984369 AW157545 BE221486 H99016 AU159025 AI074496 AI494516 BE245950 AA704385 AA280862 AI479595 AI369776 BE671398 T05538 AA682249 BI677303 BE645335 AI359434 H92868 D52599 D53609 D54715 T06015 BE222174 AI954706 D53218 D53787 R69889 W86896 AI497670 R70771 BF309414 BE620147 BG910597 AW964968 BE836120 AL579715 H56512 D55956 BI044097 AL555239 BF220278 AA081991 AI819544 AW001573 AW131600 AI858764 D52367 W22034 BG818979 BG024561 BE702779 BI458863 BI910399 BG707755 BF348284 H10055 BI086315 BE620574 H41088 BG119517 W23267 W21941 AA328817
400209 16640.1 X78817 NM_001666 D50921 AW002308 AW575456 BF507511 AW467767 AI910663 BF905778 BG251264 AL562106 AI890538 AW769258 AI590391 AI913055 AW083235 AI078474 AI925022 AW504628 AW129725 BE466589 AW002786 AW591760 AI968816 AW006268 AW593787 BG236814 AW769893 AW407608 AW075982 AI248207 AI762509 AI812070 AI249937 AW083561 AW080697 BF663046 BG745612 BG979546 AW793245 BI014177 AL519126 BE675314 AW806520 BI870778 BF879549 BE714919 BF847786 BG684161 AV695278 BG491029 BE793244 BE830893 BE798121 R09703 BI013066
444825 19904.1 AV659361 BE075267 BF743302 AL549208 AI950002 AI224961 AI471552 AI356537 AA768943 AA677028 AI358509 AI147596 AI208057 AI042009 AA156840 AA156603 AA151281 AA151341 N73171 AL540476 AI950893 BG960775 AL573355
414991 17851361 D78831 G17898 D78863
432236 1001131 1 AW747857 BI062758 AW629481 AA837630 AA557850 AA531132 AW973966 AW747856
417527 24318311 AA203524W88451
425645 12830681 BE539344AA361027
455608 14789021 BF328781 BE011406 BE011437 BE011402 BE011395 BE011428 BE011421 BE011407
418512 122256 BM046773 AA224297 T33786 T08951 T09274 T08592 T30936 AA350905
407393 68071 NM 018485AB038237
400178 8404 U69668 AA448366 X63105 BC016514 BE694436 AI655840 AW235355 BG427984 AA612862 AA448223 BM145813 BM194565 AI870824 BE973573 BM148408 AA448232 AA454176 AA740959 AA884391 AA808545 AW070759 BM144223 N75518 BE542983 BE241942 AI124022 AA761687 BF908518 BF907890 R11490 AL536642 BF109180 AA953881 AI783716 BE622908 AI621005AW148784AI690114AW275000 AI765790 BF222859 AW167268 AI990460 AW300443 AA779660 AI620568 BF115024 BE504703 AW628332 AI922851 BE006636 AU158376 AI168279 AA809916 AI469757 AA830828 AA830388 N64324 AI049683 AA970275 BF477364 BG261301 AA326388 AU150565 AU158374 AA687967 N58510 AI650450 AL549572 BF349280 BF349269 BM463016 AW836798 AL120958 AW836891 AW385525 BE175733 BE175727 BE175723 BF092430 BI061782 AU135358 BE175731 BE175754 BE175756 BE841747 BF798384 AU128251 BF095246 BG223262 AW847833 AL536643 AW366516 AW391532 BE934857 BF925057 AW438446 R86246AW179270 BE087782 BI832144
410927 3618.2 AW956025 AW956024 BE550261 BF747649 BF802668 AA369961 AV747207 AW973072 BE467756 N51927 AA531539 AW241296 AI797097 BI492823AW021896 F10837 BE715542 BE715487 AW087443 AA533638 R51354AW131541 R51852 N53741 R39257T77635 BF955795 BF331656 F13236 AW810749 449343 14470.1 AK055378 BE896063 AV722833 BI032095 BF952019 BG547204 AI151418 W03542 W60401 AI346936 AA862855 W60310 N72501 BF963436 C04881 H90060 AA001203 AI863984 AI932612 AI499771 AI187944 AA501896 AA714924 H00689 AA918680 AA573996 AA521308 AW182868 BF996707 AA908959 AI628880 AW173363 AW665845 AA130178 AI818267 AI653663 AI828924 AA746655 AI951984 AI635625 AI093113 AI377976 AI624029 AI418242 R76291 W92652 AI207798 AV706224 AA742467 AA641806 W61229 AA130170 AA160170 H85007 W72474 W61163 H97873 AL047509 R76567 AA812071 H81599 AA021275 H85004 H85894 BG537537 BF830518 W76228 W46673 Z43839 R78710 C01747 H00789 BI036345 W92828 BE150445 AW380821 AW173095 H85630 H81598 H86032 R84855 R13223 AA774992
432639 1237887.1 AW973785 H60163 AA557608 417479 2356588.1 A1057052 AI241633 T89416 426477 1296538.1 AA379611 AA379464 AA379463 418342 295203.2 BG025680 AW890852 BE002723 BE763824 400275 18707 1 NM 006513 BC009390 X91257 BC000716 B 450041 BI771139 AV710955 AU120415 AU141179 AU121081 BE409287 AU141397 AU122238 BI256788 BE386217 AU143368 AU133780 AU139704 BG531086 BE268235 BE545230 AU143414 AV761720 AU129842 AU143343 BE270064 BG473378 BE298813 BI772360 BE617354 AU140124 BE277005 BG746716 BE814960 AW161287 AV762084 BG898985 AW674875 AA313975 AV749916 AA374328 BM011248 AU098465 AW238888 BG940091 BG284599 AW410037 AA378483 D49914 AL573323 AL549819 AL572282 AL572871 AL568117 AL571945 AL547790 AL581217 AL514659 AL573926 AL540816 AW410038 BI262249 BG284713 AI659394 AI093582 AW965846 AA652206 AI686014 AA654357 AU146982 AW273447 AW157715 AW574750 BG683509 AW887824 AI818522 AA703770 BE542873 AA515504 AU154982 AA831254 AA828521 AI088602 AA854654 AA190869 BF062816 AA464944 BG261335 AI003584 BG402820 AA932098 W68695 AW182900 W37334 AI073864 C17924 C18528 AI299318 BF154399 BG319570 BF764242 BF764209 AI620320 T06029 BF447193 F29285 AL548949 BI333775 BE743602 BE618230 BE268139 BF036434 BE562718 BG774381 AA659833 AA297649 AA010945 BG105512 BE269205 T32623 BG015679 AL518518 AL517118 AL538396 AI049861 AL581976 AV752041 W26586 BE181609 AI963016 BG057603 AI720256 AA844560 AA055570 BE619606 C17428 AI042174 N93945 N69743 BF795208 AW057940 BI091399 AW975179 AA909936 H28712 W65445 AL515439 W37117 H66514 T85737 W37369
414087 1632850 1 W19712 BE247277
423387 2612.2 L13288 AA928785 AI608912 AW872978 AA565655 AI022915 AI304920 AI564366 AI668793 AI094557 T60038 R72302 H45409 AA508805 R46356 AA418798 BM129553 BM129126 BM129292 BM128865 AI808418 AI689932 AI806573 BF431808 AW872985 AW166269 H73241 T16182 AI264547 R73391 R72085 R72840 T83751 X75299 BF754348 R94105 AW449839 R73300 NM.004624 AI797007 BE045543 BF110021 BF754250 T83923 AW884084 AA903896 AA418962 L20295 R72351 H45098 AA961010 R73210 R46451 AW884085 BI022902 BI763932 BI910138
412283 1163164 1 AW936035 AW935951 AW935789 AW935881 AW936018 AW935892 BE069084
409745 MH1944.5 BI030997 AA921874 AW188822 BI027862 AI347618 AI361453 AI088754 AW207491 AA077391 BG012775 BG997382 AA286833 AA150722 BI007625 BI027864 BI009100 BI006275 BI006270 BI031000 BI029864 BI006277 BI007627 BI006266 BI006981 BI006990 BI007763 BI007762 BG997377 AA150780 BI033518 BI027818 BG015789 BI033807AA341445
413285 12794 9 BE078405 BE078404 BE168534
426578 358276 1 AV742719 R23027 R63874 AA381749
438005 694209 2 BG542693 D63271 T94955 AA774994
454701 352355 1 BF697879 BG984482AW854930 AW854941 AW814115AW814431 AW814190 BF325887 BF325890 BF985536
411140 1071177.1 AW819463 AW819514 AW819617 AW819618 AW819609
407013 2073 7 U35637 AA192323 AA194508 BG011583 F25712 AL596820 BE185376
432925 225876 1 AA878324 AI619686 AI014377
417670 2139687.1 T85948 R07785T86972
400189 2140.1 Y08200 NM 004581 BC003093 BE733834 BI753321 BG773890 BF091906 BI917541 AI023762 AA587230 BF435086 AI264262 AI687392 AI810536 AW589886 AI244419 AA749261 AA535435 AW205689 AI765770 AI765431 C02465 AW305347 AI818456 AA322111 AW381845 AW381829 AV749407 AA811636 AU159893 AA603065 AA652542 AI468678 R49616 AW381863 BE389867 BE182387 BF087771 AA527551 AA134051 AA831504 AA134052 AI871759 AW089048 BI913532 AA367709 BG828155 BF093014
411331 1076355 1 AW837178 T77002 F13038
418177 6503.2 AK056654 AJ420421 AI127111 AA705921 AA749298 AA776967 AI343768 AW070583 AA766587 AA804876 AA460658 AA394137 W72279 AW071467 AI343843 AA393817 AW769379 AA861873 AA715043 AW512448 AI452856 AI819873 T17354 AW779778 BF477620 AI783605 AI624523 AA261906 AA514931 BI964124 AW576481 AI864544 AA490863 AA860972 BI963076 AI632879 AA291985 AA255873 BI966876 BI963833 Z38970 BI495302 BI495301 AI784395 AU185472 AA652150 AA652026 D20449 BI088167 BI260636 BE869946 AI935271 BI792882 AI762915 AI809275 AI813351 BF447139 AI052069 AI057127 AA398950 AA291984 AA292934 AA262543 BF760287 R64455 R72980 H90786 BE698016 AW959314 BI031449 AL574617 AA776284 AA393770 BM455617 BI602104 BI793150 N36710 H59529 BI005937 BI600748 BF085914 BF085907 BF835429 BF835210 BF085926 AA226136 BF836829 BF836606 BM007373 AI369807 BF085930 W25119 BI252884 BI001270 BE549079 BF238403 R56934
439518 23842.1 AF086341 W76326W72300 400211 3532.1 NM.003899 D63476 BM456434 AA778936 AA452871 AI052466 AW014138 AA448725 BE673088 AW028198 BI856378 BM150466 BM150674 BM148451 AW500880 AA180228 BE243507 BM144903 AA333656 AW503767 AA305470 AW504819 AA978194 AW500776 BE872488 AI032663 AA704686 AA652189 AA179463 AL535925 BE275744 BE277708 BE275715 AW504259 AA354483 BE244197 BE246232 D17055 AW013876 AW014877T09464T08407AA830246AW897881 BE501192 BE501195AL044534AA258853 BI037915 AA448037 BM461769 BI825965 BE763352 AW167531 Z45588 AV721881 AA527273 AI573219 AA457036 AW439651 AW264418 AA577618 AI802954 AA902292 AA468752 AI380374 AA722690 AI867708 AA916982 AI291576 AW190427 AI338089 AI653744 AI306665 AW513541 AW440077 AI370014 AA904269 AW188378 AI671644 AW193386 AI261832 AA775336 BF436811 AI582703 AI278635 BE440186 AA617898 AA648948 BI491837 BF590311 AA448633 F27048 F37022 AW770819 AA258808 AI369564 AW503675 AA777194 BE501048 BF222087 AA042973 AI868087 AA911460 Z41274 AI919082 T16746 AA447634 AI282427 F22456 T15901 AA825298 AW007436 BE934303 BG981939 AW373814 BM151638 AW956921 BM150080 BM153173 BM147451 BF953992 AA916696 AW444935 M78398 AW581147 AW608258 AA651910 AA132152 AW806295 T30326 D20054 AA310837 T06543 BM194508 BM193225 BM469348 AW964920 AA325930 BI833627 AW952193 AA738189 AA321051 BG987199 BF953967 T08890 BE869543 BG742857 BG988685 AA456880 BG001842 BF809452 AW892083 BF944342 T49551 W69981 BF764519 T15869 AA132030
426409 320121 1 AW964027 AA377709
459357 1086411 1 AW848421 T71427
411226 1073516 1 T62567 AW833022 AW833054
415516 1875286 1 H20760 R15237Z43915 BF372479 F11411
433090 7504 2 AB038318 BC008888 BE905346 BE301941 AA705936 AW014954 BE378742 AI720050 BE395327 BG951204
436206 31207.1 AK001451 AU151098 AW515640 AW439618 AI671555 AW304963 AA565885 AI829434 AW590882 AI889234 AW117522 AA847824 AI636224 AA883540 AA169387 AW771571 AI130803 BF438773 AA088710 AI972691 AI972638 AI762358 AI473907 AI925905 AA502277 BG943806 BG218468 AA194853 AU128875 AA306025 BG986896
438141 1173217 1 AA778849 AW946871 AW946782AW946955
439463 23351 1 AF086283 W69200 W69304
454564 1061820 1 AW807573 AW807572
426481 1229053 1 AW963941 AA379825 AW963944 AA379564
426005 MH790.19 NM 054014 X52220 BC005147 BI551326 AI393601 AW592611 AA608921 AA731598 W96331 AW590007 AI076813 AI022644 AA158365 AI699321 AI146747 AW296894 H85337 AA017692 AA354519 AA018512 D20081 R02704 AA825671 AA017651 AL135600 R02585 AA018849 BG749616 BF689840 R85326 AA677955 AA702354 AI076645 AI057359 H53178 W86484 H53074 BG988909 AW962456 AA367326 AA377499
416508 1974161.1 R39769T53143 H60012
408087 633688 1 AW150645 AW811024 AW811148AW811068
433434 194862.1 BF812525 AW504832 AI972567 AA588429 AI299694
437158 59575.1 AL050068 AA160485 AW173544AW296506AW439860AI521563 AI702529 AI393606 AW138323 AA570109 H19504 BM021968 BF063327 BF593552 AA630766 AI597717 AI807128 AA523012 AI356250 AW451857 AA974203 AI762577 BF512552 AW007307 BE675286 AW450602 AA962057 AW516069 AI582546 BF221924 BF222543 AI801808 AW468599 AW000736 AI866625 AW235356 BM021837 AA911956 AI680606 W86516 T03370 AW611634 H41653 AI468349 H19588 AW090198 AW043993 R39847
411902 1141058 1 AW875344 AW875287 AW875285 AW875286 BF361295 AW875402 AW875400
455840 1518844.1 BE145816 BE145897 BF349721 BE145885
430975 56593 2 AK057266 BI767614 BI828586 AW069362 BI829572 AI826091 BI819382 AL040402
TABLE 49C Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham 1 et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I etal , Nature (1999) 402489495 Strand Indicates DNA εtrand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
402260 3399665 Minus 113765-113910,115653-115765,116808-11694
401027 7230983 Minus 70407-70554,71060-71160
400991 8096825 Plus 159197-159320
406137 9166422 Minus 30487-31058
404083 9944029 Minus 16650-17082
404440 7528051 Plus 80430 81581
400792 7382433 Plus 134339 134593
404289 2769644 Plus 15049-15286,30267-30457
401083 3242744 Plus 33192-33360
402211 7689783 Minus 67414-68229
402705 8782736 Plus 89961-90114,90773-90895,91131-91261
402233 7690102 Plus 90281-91477
405370 2078469 Minus 38980-39111
400846 9188605 Plus 39310-39474
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
401345 9926424 Plus 148042-148392
400843 9188605 Plus 5863-5970,7653-7784,8892-9023,9673-9807,
406364 9256114 Minus 50715-50833
405490 7705240 Plus 20683-20850
400755 8119083 Minus 120084-120889
404276 9885189 Plus 127624-127856
402915 7406502 Minus 140-276
405616 5649378 Minus 2782-3308
400847 9188605 Pluε 44643-44835
402328 4464283 Minuε 13758-13922,14558-14752
405369 2078469 Minus 34183-34357,35686-35751
400845 9188605 Plus 34428-34612
403716 7239669 Plus 86899-87122
402447 9796640 Plus 47605-47729,51696-51821,52070-52257,5330
404140 9843520 Plus 37761-38147
405516 9454624 Plus 112707-112876,113676 113854
405110 8096888 Minus 118940-119100
403608 8308266 Minus 121321-121476
401241 4827300 Minus 30503-30844,31056-31248
405102 8076881 Minus 120922-121296
404185 4572584 Minus 129171-129327
405545 1054740 Plus 118677-118807,119091-119296,121626-12182
405411 3451356 Minus 17503-17778,18021-18290
405602 4753260 Plus 44647-44778
403391 9438337 Plus 42410-42544,83317-83540,86840-86922,8797
403869 7280046 Minus 34379-34583
404942 7382153 Plus 92095-92252
403142 9444521 Plus 89286-90131
400844 9188605 Plus 24746-24872,25035-25204
402704 8782736 Plus 37368-37493
402833 8918545 Plus 26987-27778
401851 7770425 Minus 146443-146664,147794-147971,148351-14848
401242 4827300 Minus 32616-32863
401943 4914397 Plus 65925-66371
402807 6456148 Minus 101542-101660,103476-103656
402603 9909396 Minus 141663-141852
405328 3253114 Pluε 21399-21583
402974 9663349 Plus 124035-124321
400987 8086488 Minus 22052-22185
403335 8568884 Plus 112307-112524,114074-114703
401113 9966541 Minus 19419-19959
401185 9625304 Minus 177393-177691
404537 8247909 Minus 188775-189573
405266 4156171 Minus 63337-63552
402615 9926801 Plus 131390-132157
400566 9884730 Plus 64486-64714
403212 7630897 Minus 156037-156210
403290 8083176 Plus 19288-20076
401342 9908882 Plus 3096-3242
400471 9931670 Minus 105629-105760
405588 5002511 Plus 46180-46366
400539 7574902 Plus 8559-8721
403743 7652003 Minus 136463-136646
403912 7710730 Minus 72000-72290,72431-72700,72929-73199
405099 8074292 Minus 114365-114514,128635-128831
401445 8218584 Minus 93700-93886
405480 2766593 Plus 33325-33659
402183 7658390 Minus 100618-104298
400749 7331445 Minus 9162-9293
406139 9166768 Minus 72397-72602 402129 7704953 Minus 166156-166365
400645 8117693 Minus 58471-58716
403201 9958297 Minus 109782 109934
403609 8308266 Minus 125974-126320
400719 8118911 Minus 44579 44656,45294-45487,46449 46641
403088 8954241 Plus 169894-170193 170504-170806
403328 8469086 Minus 120428-120703
403305 8099945 Plus 114632-114805
401702 1871197 Minus 68182-68325
400777 8131663 Plus 70745-71121
404956 7387343 Plus 55883-56203
401917 9502466 Plus 25054-25229
401984 4454511 Plus 103825-104024
406303 8575868 Plus 173622-173786
Table 50A lists about 414 genes up-regulated in non seminomatouε mixed germ cell testicular cancer compared to normal adult tisεueε These were selxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" non semmomatous mixed germ cell testicular cancer to "average" normal adult tisεues was greater than or equal to 2 The "average" non seminomatouε mixed germ cell testicular cancer level was set to the 85th percentile amongst πoπ-semmomatous mixed germ cell testicular cancers The "average" normal adult tisεue level was set to the 95th percentile amongst non malignant tissues In order to remove gene-spxific background levels of non-spxific hybndization, the 10th percentile value amongst the non malignant normal body tisεueε waε subtracted from both the numerator and the denominator before the ratio was evaluated
Table 51 A lists about 518 genes up-regulated in semmomatous testicular cancer compared to normal adult tisεues These were selxted from 59680 probeεets on the Affymetπx/Eoε Hu03 GeneChip array εuch that the ratio of "average" εemmomatous testicular cancer to "average" normal adult tisεueε waε greater than or equal to 2 The "average" semmomatous testicular cancer level was set to the 85th percentile amongst seminomatouε testicular cancers The "average" normal adult tisεue level was εet to the 95th percentile amongεt non- maligπant tissues In order to remove gene-specific background levels of non-specific hybndization, the 10th percentile value amongst non malignant normal body tissueε was subtracted from both the numerator and the denominator before the ratio waε evaluated
Table 52A lists about 673 genes up regulated in testicular cancer (πon-semmomatous and εeminomatouε) compared to normal adult testicular tissues These were selxted from 59680 probesets on the Affymetπx Eoε Hu03 GeneChip array εuch that the ratio of "average" testicular cancer to "average" normal testicular adult tissueε waε greater than or equal to 6 The "average" testicular cancer level was εet to the 75th percentile amongεt testicular cancers The "average" nomial adult testicular tissue level was set to the 95th percentile amongst non-malignant testicular tisεues In order to remove gene εpecific background levels of non-spxific hybndization, the 10th percentile value amongεt non malignant normal body tissues was subtracted from both the numerator and the denominator before the ratio was evaluated
Table 53A lists about 735 genes up regulated in testicular cancer (non-seminomatouε and εemiπomatous) compared to normal adult tissues These were selxted from 59680 probesetε on the Affymetnx/Eoε Hu03 GeneChip array εuch that the ratio of "average" testicular cancer to "average" normal adult tisεueε waε greater than or equal to 3 The "average" testicular cancer level was set to the 95th percentile amongεt testicular cancers The "average" normal adult tissue level was set to the 95th percentile amongst non- malignant tissues In order to remove gene-specific bxkground levels of non spxific hybridization, the 10th percentile value amongst non-malignant normal body tissues was εubtrxted from both the numerator and the denominator before the ratio was evaluated
Table 54A lists about 476 testi-εpxific geπeε downregulated in testicular cancer (non-semmomatous and semmomatous) These were selxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio (R1 ) of normal testi to normal adult tiεεueε waε greater than or equal to 3 R1 was calculated as the mean number of interquartile range values over the median normal adult body uεεue expression among normal testicular sampleε The ratio (R2) of "average" normal teεti to "average" testicular cancer among these genes was greater than or equal to 2 The "average" normal testi level was set to the 50th percentile amongst normal testis The "average" normal testicular cancer level mas set to the 95th percentile amongst testicular cancer samples In order to remove gene-spxific background levels of non-specific hybndization, the 10th percentile value amongst non malignant normal body tisεues was subtrxted from both the numerator and the denominator before the ratio was evaluated Table 55A lists about 586 genes up-regulated in non-semmomatous mixed germ cell testicular cancer compared to normal adult testicular tisεueε Theεe were εelxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" non-seminomatouε mixed germ cell testicular cancer to "average" normal adult testicular tissueε was greater than or equal to 4 The "average" non-seminomatouε mixed germ cell testicular cancer level was set to the 95th percentile amongst noπ-semmomatouε mixed germ cell testicular cancers The "average" normal adult testicular tissue level was εet to the 95th percentile amongst non malignant testicular tissueε In order to remove gene- εpecific bxkground levelε of non-εpxific hybndization, the 10th percentile value amongst non-malignant normal testicular tissues was subtrxted from both the numerator and the denominator before the ratio was evaluated
Table 56A lists about 812 genes up-regulated in semmomatous testicular cancer compared to normal adult testicular tissueε These were selxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" semmomatous testicular cancer to "average" normal adult testicular tissues was greater than or equal to 4 The "average" semmomatous testicular cancer level was εet to the 50th percentile amongst seminomatouε testicular cancers The "average" normal adult tissue level was set to the 95th percentile amongst non malignant testicular tissues In order to remove gene-spxific bxkground levels of non-specific hybndization, the 10th percentile value amongst πon- malignant normal testicular tissueε was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 50A
Pkey Unique Eos probeset identifier number ExAccn Exemplar Accesεion number, Genbank xceεεion number
UnigenelD Unigene number Unigene Title Unigene gene title R1 Ratio of non-semmomatous mixed germ cell testicular cancer compared to normal adult tisεueε Pkey ExAccn UniGene Unigene Title R1
432666 AW204069 ESTs Weakly similar to unnamed protein 7460
432730 AI066520 Hs 131358 ESTs 5055
450581 AF081513 Hs 25195 TGF-beta 4 47 85
418696 AW959433 Hs 326290 hypothetical protein FLJ12581 4405
423458 AI204212 ESTε 3660
428664 AK001666 Hs 189095 similarto SALL1 (sal (Drosophila) like 3060
448981 AI968719 Hs 195387 ESTs 2640
407710 AW022727 Hs 23616 ESTs 2400
429486 AF155827 Hs 203963 hypothetical protein FLJ10339 19 35
451106 BE382701 Hs 25960 N MYC oncogene 1885
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 1840
420759 T11832 Hs 127797 Homo sapiens cDNA FLJ11381 fis, clone HE 18 25 424578 AK001973 Hε 150890 hypothetical protein 1786
418756 AA252254 Hε 226949 ESTs 17 20
404996 Target Exon 16 15
447534 AW953935 Hs 288655 ESTs 1580
456847 AI360456 Hs 37776 ESTε 1500
446979 AI654443 Hs 197683 ESTε 1480
438915 AA280174 Hs 285681 Williams-Beuren syndrome chromosome regi 1475
452838 U65011 Hs 30743 preferentially expresεed antigen in mela 1470
449322 AI638616 Hs 196566 ESTs 1435
418007 M13509 Hs 83169 matnx metalloprotemase 1 (interstitial 1420
448776 BE302464 Hs 30057 MRS2 (S cerevisiae) like, magnesium hom 1295
433330 AW207084 Hs 132816 hypothetical protein MGC14801 1270
410102 AW248508 Hs 279727 ESTs, homologue of PEM 3 [Ciona savignyi 1255
447188 H65423 Hs 17631 hypothetical protein DKFZp434E2135 1243
406547 Target Exon 1235
434649 AA738254 Hs 165390 ESTε, Highly similar to A40350 transcπp 1210
428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy 11 65
408908 BE296227 Hs 250822 seππe/threonme kinase 15 11 55
437099 N77793 Hs 48659 ESTε, Highly similar to S14458 laminin a 11 05
430676 AF084866 gb Homo sapienε envelope protein RIC-3 ( 1008
426866 U02330 Hs 172816 neuregulm 1 1005
446791 AI632278 Hs 195922 ESTε 1005
433159 AB035898 Hs 150587 kmesin-like protein 2 985
428479 Y00272 Hs 334562 cell division cycle 2, G1 to S and G2 to 895
427521 AW973352 ESTs 892
452291 AF015592 Hs 28853 CDC7 (cell division cycle 7, S cerevisi 890
427486 AA974433 fibroblast growth fxtor 4 (hepaπn sxr 852
425266 J00077 Hs 155421 alpha fetoprotein 850
408465 AW196940 Hs 253277 ESTε 847
444971 AI651116 Hs 148659 ESTε 835
413318 AU076607 Hs 75285 inter-alpha (globulin) inhibitor, H2 pol 835
425769 U72513 Hs 159486 Human RPL13-2 pseudogene mRNA, complete 800
409731 AA125985 Hs 56145 thymosin, beta, identified in neuroblast 795
424905 NM 002497 Hs 153704 NIMA (never in mitosis gene a)-related k 775
412265 AA101325 Hs 86154 hypothetical protein FLJ 12457 765
407340 AA810168 Hs 284289 vitiligo-associated protein VIT-1 750
453884 AA355925 Hs 36232 KIAA0186 gene product 736
422956 BE545072 Hs 122579 ECT2 protein (Epithelial cell transformi 725
432239 X81334 Hs 2936 matnx metalloproteinase 13 (collagenase 725
440119 AA865455 Hs 125331 ESTs, Moderately similar to unknown [H s 722
431840 AA534908 Hs 2860 POU domain, class 5, transcnption fxto 7 13
435918 AF263538 Hs 86232 growth differentiation factor 3 713
412537 AL031778 nuclear transcnption fxtor Y, alpha 708
416658 U03272 Hs 79432 fibπlhn 2 (congenital contrxtural ara 705
428916 AF003001 Hs 194562 telomeπc repeat binding fxtor (NIMA-in 688
424085 NM 002914 Hs 139226 replication fxtor C (xtivator 1) 2 (40 675
453392 U23752 Hs 32964 SRY (sex determining region Y) box 11 675
437052 AA861697 Hs 120591 ESTε 675
425427 AI652662 Hs 157205 branched chain aminotranεferaεe 1, cytoε 6 2
443523 AK001575 Hs 9536 hypothetical protein FLU 0713 671
457465 AW301344 Hs 122908 DNA replication fxtor 662
442832 AW206560 Hε 253569 ESTε 654
427711 M31659 Hε 180408 εolute camerfamily 25 (mitochondnal 630
453913 AW004683 Hε 78934 mutS (E coli) homolog 2 (colon cancer, 630
448588 AI970276 Hε 156905 KIAA1676 612
436608 AA628980 Hs 192371 down εyndrome critical region protein DS 609
415857 AA866115 Hs 127797 Homo εapienε cDNA FU11381 fiε, clone HE 595
412642 BE244598 Hs 809 hepatxyte growth fxtor (hepapoietiπ A, 585
443068 AI188710 ESTε 585
438450 AI050866 Hε 65853 nodal, mouεe, homolog 581
441287 AW293132 Hε 131373 ESTs 580
425572 AB011076 Hε 158307 undifferentiated embryonic cell transcπ 576
416747 AW876523 Hε 15929 hypothetical protein FU 12910 575
436902 AW247145 Hε 192729 ESTs 570
441627 AA947552 Hε 58086 branched chain aminotranεferaεe 1, cytos 560
440304 BE159984 Hε 125395 ESTs 560
432407 AA221036 Hε 13273 gb zr03f12 r1 Stratagene NT2 neuronal pr 556
436812 AW298067 gb UI-H-BWO-ajp-g-09-O-UI s1 NCI_CGAP.Su 555
423673 BE003054 Hs 1695 matnx metalloproteinase 12 (mxrophage 551
431354 BE046956 Hs 251673 DNA (cytosιne-5-)-methyltraπsferaεe 3 be 551
430044 AA464510 Hs 152812 ESTε 547
437036 AI571514 Hs 133022 ESTε 545
435663 AI023707 Hs 134273 ESTε 540
427667 AK001279 Hs 180171 Homo εapienε cDNA FLJ10417 fiε, clone NT 540
416111 AA033813 Hs 79018 chromatin assembly factor 1 , subunit A ( 521
447254 NM 004153 Hs 17908 oπgin recognition complex, subunit 1 (y 515
434551 BE387162 Hs 280858 ESTs, Highly similar to A35661 DNA excis 515
430272 X04898 Hε 237658 apolipoprotein A-ll 512
427961 AW293165 Hε 143134 ESTε 505
424315 AW614850 Hs 193384 putatative 28 kDa protein 505
409798 AA248587 Hs 30237 ESTs, Weakly similar to ALUB.HUMAN "" 500
418477 AW022983 gb df46h12 y1 Morton Fetal Cxhlea Homo 500
418378 AW962081 gb EST374154 MAGE resequences, MAGG Homo 495 430255 AK000703 Hs 323822 Homo sapiens mRNA for KIAA1551 protein, 494
443537 D13305 Hs 203 cholecystokmin B rxeptor 4 92
431494 AA991355 Hs 298312 hypothetical protein DKFZp434A1315 490
416661 AA634543 Hs 79440 IGF-II mRNA binding protein 3 4 85
423642 AW452650 Hs 157148 hypothetical protein MGC13204 480
449592 AI655494 Hs 195718 ESTs 475
407300 AA102616 Hs 120769 gb zn43e07 s1 Stratagene HeLa cell ε393 473
420333 AJ001383 Hs 97084 lymphxyte antigen 94 (mouεe) homolog (a 468
446700 AW206257 Hs 156326 Human DNA sequence from clone RP11-145L2 461
445537 AJ245671 Hs 12844 EGF-like domain, multiple 6 460
448966 AW372914 Hs 86149 phosphomoεitol 3-phoεphate binding prot 4 50
439570 T79925 Hs 269165 ESTs, Weakly similar to ALU1.HUMAN ALU S 450
440006 AK000517 Hs 6844 NALP2 protein, PYRIN-Containmg APAF1 Ii 448
402145 Target Exon 448
408750 BE294069 Hs 93581 hypothetical protein FLJ 10512 447
453289 AI188161 Hs 144627 ESTs 445
430252 AI638774 Hs 105328 testeε development-related NYD-SP20 440
422689 AW856665 gb RC3-CT0297-290100 013-d03 CT0297 Homo 432
426427 M86699 Hs 169840 TTK protein kinaεe 430
420047 AI478658 Hs 94631 brefeldm A-mhibited guanine nucleotide 420
430287 AW182459 Hs 125759 ESTs, Weakly similar to LEU5.HUMAN LEUKE 4 18
419635 NM 005033 Hs 91728 polymyositis/scleroderma autoantigen 1 ( 415
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient, yeast, h 4 10
438188 AA779975 Hs 128859 ESTs 4 10
435514 AW592804 ESTs 4 10
442333 AI650877 Hs 129302 ESTs 405
413627 BE182082 Hs 246973 intron of Bicaudal D homolog 1 400
445140 AI650599 Hs 197913 ESTs, Weakly similar to SCP3 MOUSE SYNAP 400
448038 AW015073 Hs 232026 ESTs, Weakly similar to R052.HUMAN 52 KD 4 00
458814 AI498957 Hs 170861 ESTε, Weakly similar to Z195_HUMAN ZINC 395
419423 D26488 Hs 90315 KIAA0007 protein 395
440527 AV657117 Hs 184164 ESTs, Moderately similar to S65657 alpha 3 95
441553 AA281219 Hs 121296 ESTs 395
432415 T16971 Hs 289014 ESTs, Weakly similar to A43932 mucin 2 p 3 91
409757 NM 001898 Hs 123114 cystat SN 389
432281 AK001239 Hs 274263 hypothetical protein FLJ10377 3 88
450351 BE547267 Hs 59791 hypothetical protein MGC13183 3 85
403780 C4001759 gι|133250|sp|P19474|RO52 HUMAN 384
421917 AB028943 Hs 109445 KIAA1020 protein 384
417153 X57010 Hs 81343 collagen, type II, alpha 1 (primary oste 384
429120 AK001673 Hs 196530 hypothetical protein FLJ10811 3 82
410193 AJ132592 Hs 59757 zinc finger protein 281 380
453922 AF053306 Hs 36708 budding uninhibited by benzimidazoles 1 380
415829 AW450198 Hs 163742 ESTs 378
440953 AI683036 Hs 124135 Homo sapiens cDNA FLJ13051 fis, clone NT 377
439780 AL109688 gb Homo sapienε mRNA full length insert 370
422938 NM 001809 Hs 1594 centromere protein A (17kD) 368
415947 U04045 Hs 78934 mutS (E coli) homolog 2 (colon cancer, 3 66
423123 NM 012247 Hs 124027 SELENOPHOSPHATE SYNTHETASE , Human εelen 365
420900 AL045633 Hs 44269 ESTε 365
426572 AB037783 Hs 170623 hypothetical protein FLJ11183 365
426496 D31765 Hs 170114 KIAA0061 protein 360
452461 N78223 Hs 108106 tranεcπption fxtor 360
418379 AA218940 Hs 137516 fidgetin-like 1 350
442573 H93366 Hs7567 branched chain aminotransferase 1, cytos 348
428301 AW628666 Hε 98440 ESTs, Weakly similar to I38022 hypotheti 345
419384 AA490866 Hs 39429 ESTs 344
453932 AW006303 Hs 329296 ESTs, Weakly similar to (defliπe not ava 343
446293 AI420213 Hs 149722 LIM domain transcnption fxtor LIM-1 (h 341
422094 AF129535 Hs 272027 F-box only protein 5 340
418661 NM 001949 Hs 1189 E2F transcnption fxtor 3 340
423198 M81933 Hs 1634 cell division cycle 25A 3 39
424153 AA451737 Hs 141496 MAGE-lιke 2 338
417705 AW134952 Hs 175220 hypothetical protein FLJ 14541 337
443715 AI583187 Hs 9700 cyclin E1 334
420281 AI623693 Hs 323494 Predicted cation efflux pump 334
449571 AW016812 Hs 200266 ESTs 334
424687 J05070 Hs 151738 matrix metalloproteinase 9 (gelat ase B 331
452807 AA028933 Hs 162434 ESTε 331
422756 AA441787 Hs 119689 glycoprotein hormones, alpha polypepbde 330
421650 AA781795 Hs 122587 ESTs 330
418355 L42563 Hs 1165 ATPase, H? transporting, nongastπc, alp 328
438494 AA908678 Hs 130183 ESTs 323
424568 AF005418 Hs 150595 cytochrome P450, subfamily XXVIA, polype 322
433764 AW753676 Hs 39982 zinc finger protein RINZF (NM 023929) 320
427642 R40761 Hs 9834 ESTs 320
414747 U30872 Hs 77204 centromere protein F (350/400kD, mitosm 318
403432 NM.001622 Homo sapienε alpha 2-HS-glycop 3 18
442618 R56222 Hs 26514 ESTε 317
415799 AA653718 Hs 225841 DKFZP434D193 protein 317
416000 R82342 Hs 79856 ESTε, Weakly similar to S65657 alpha-1 C- 3 15
450431 AW136797 Hs 266041 ESTε 3 13
433800 AI034361 Hs 135150 lung type I cell membrane-aεsxiated gly 312 430835 AI240006 Hε 192326 ESTε 3 12
419741 NM 007019 Hs 93002 ubiquitin earner protein E2-C 310
417791 AW965339 Hs 111471 ESTs 310
434609 R76593 gb yι60c11 r1 Soares placenta Nb2HP Homo 305
430253 AK001514 Hs 236844 hypothetical protein FLJ 10652 304
411975 AI916058 Hs 144583 ESTs 301
430491 AL109791 Hs 241559 Homo sapiens mRNA full length insert cDN 300
413943 AW294416 Hs 144687 Homo sapiens cDNA FLJ12981 fis, clone NT 299
440207 AI371978 Hs 128326 ESTs 298
435726 BE535787 Hs 113170 ESTs 297
432840 AK001403 Hs 279521 hypothetical protein FLJ20530 297
450149 AW969781 Hs 132863 Zic family member 2 (odd paired Drosophi 295
435373 AW665538 Hs 117689 ESTs 293
452571 W31518 Hs 34665 ESTs v 293
454679 AW813110 gb CM4-ST0189 051099 021405 ST0189 Homo 291
414972 BE263782 Hs 77695 KIAA0008 gene product 290
437496 AA452378 Hs 146668 Homo sapienε mRNA, cDNA DKFZp547J125 (fr 290
420092 AA814043 Hs 88045 ESTε 289
438378 AW970529 Hs 86434 hypothetical protein FLJ21816 289
434414 AI798376 gb tr34b07 x1 NCI_CGAP_Ov23 Homo εapiens 287
422746 NM 004484 Hs 119651 glypican 3 2 87
446258 AI283476 Hs 263478 ESTε 286
444371 BE540274 Hs 239 forkhead box M1 286
409517 X90780 troponin I, cardiac 285
414034 U89277 Hs 305985 eariy development regulator 1 (homolog o 284
443169 AI038687 Hs 133338 ESTε 284
447519 U46258 Hs 339665 ESTε 284
453785 AI368236 Hs 283732 ESTε, Moderately similar to ALU1.HUMAN A 284
406687 M31126 matnx metalloproteinase 11 (stromelysin 283
416201 AA467752 Hs 195161 ESTs 283
412140 AA219691 Hs 73625 RAB6 interacting, kinesm like (rabkmes 283
457191 AI376228 Fπend leukemia virus integration 1 282
410704 BE076754 gb CM1-BT0601-180200421-b10 BT0601 Homo 281
413646 BE155042 gb PMO HT0349-101299 002-E04 HT0349 Homo 280
421307 BE539976 Hε 103305 Homo sapienε mRNA, cDNA DKFZp434B0425 (f 275
427719 AI393122 Hε 134726 ESTs 275
451684 AF216751 Hε 26813 CDA14 275
414590 NM_000506 Hε 76530 coagulation factor II (thrombin) 274
442032 AW016786 ESTs 273
437123 AL049285 Hε 302053 Homo sapiens mRNA, cDNA DKFZp564M193 (fr 272
446528 AU076640 Hs 15243 nucleolar protein 1 (120kD) 272
442007 AA301116 Hs 142838 nucleolar phosphoprotein Nopp34 271
438180 AA808189 Hs 272151 ESTs 270
453900 AW003582 Hs 226414 ESTs, Weakly similar to ALU8_HUMAN ALU S 270
423765 R23858 Hs 143375 Homo sapiens, clone IMAGE 3840937, mRNA, 269
420949 AA934063 Hs 13836 ESTs, Weakly similar to 138022 hypotheti 269
413813 M96956 Hs 75561 teratocarcinoma-deπved growth fxtor 1 268
433914 AF108138 Hs 112160 Homo sapiens DNA helicase homolog (PIF1) 267
445413 AA151342 Hs 12677 CGI-147 protein 266
448769 N66037 Hs 38173 ESTs 266
411022 AW936378 gb QV4-DT0021-301299-071-f05 DT0021 Homo 265
423600 AI633559 Hs 310359 ESTε 265
447175 AI365208 Hs 293606 ESTε 265
414151 AW976468 Hs 257245 ESTε 265
448877 AI583696 Hs 253313 ESTε 262
427584 BE410293 Hs 179718 v-myb avian myeloblastosiε viral oncogen 261
440591 AA431599 Hs 132799 hypothetical protein FU23451 261
449665 AI655391 Hs 143375 Homo εapieπs, clone IMAGE 3840937, mRNA, 261
453775 NM 002916 Hs 35120 replication fxtor C (activator 1) 4 (37 260
429228 AI553633 ESTs 260
410929 H47233 Hs 30643 ESTε 259
427528 AU077143 Hs 179565 minichromosome maintenance deficient (S 258
446142 AI754693 Hs 145968 ESTs 256
445093 AI207197 ESTs 256
413686 AI469213 Hs 71404 ESTs 2 55
447733 AF157482 Hs 19400 MAD2 (mitotic arrest deficient, yeast, h 255
420218 AW958037 πbosomal protein L4 255
407275 AI364186 gb qw34h07 x1 NCI CGAP_Ut4 Homo sapienε 255
414312 AA155694 Hs 191060 ESTε 255
421535 AB002359 Hs 105478 phosphoπbosylformylglycinamidiπesyntha 255
439979 AW600291 Hs 6823 hypothetical protein FU 10430 252
426075 AW513691 Hs 270149 ESTs, Weakly similar to 2109260A B cell 251
435096 AA664977 gb nu73b07 s1 NCI_CGAP_Alv1 Homo εapienε 250
422468 AA355210 gb EST63589 Jurkat T-cells V Homo sapien 250
449576 AW014631 Hs 225068 ESTs 250
415684 D59356 sorbitol dehydrogenase 2 50
452226 AA024898 Hs 157103 ESTs 250
421451 AA291377 Hs 50831 ESTs 250
424308 AW975531 Hs 154443 minichromosome maintenance deficient (S 250
418203 X54942 Hs 83758 CDC28 protein kinase 2 249
453941 U39817 Hs 36820 Bloom syndrome 249
413762 AW411479 Hs 848 FK506 binding protein 4 (59kD) 249
449655 AI021987 Hε 59970 ESTs 249 430521 NM.016383 Hs 242183 HOM TES-85 tumor antigen 249
447444 AK000318 Hs 18616 hypothetical protein FU20311 248
414618 AI204600 Hs 96978 hypothetical protein MGC10764 248
445363 NM 005993 Hs 12570 tubulin εpecific chaperone d 247
452404 AW450675 Hs 212709 ESTε 246
444823 BE262989 Hs 12045 putative protein 246
427675 AW138190 Hs 180248 zinc finger protein 124 (HZF-16) 245
444159 AF116846 Hs 10431 dead ringer (Drosopfιιla)-lιke 2 (bπght 245
436211 AK001581 Hs 334828 hypothetical protein FLJ10719, KIAA1794 245
416734 H81213 Hs 14825 ESTs Weakly similar to KIAA1503 protein 245
433183 AF231338 Hs 222024 transcnption factor BMAL2 245
447350 AI375572 v erb-a avian erythroblastic leukemia vi 245
428728 NM 016625 Hs 191381 hypothetical protein 243
407325 AA291180 Hs 328476 ESTs, Weakly similar to alternatively sp 243
410276 AI554545 aπgιopoιetm-2 242
444670 H58373 Hs 332938 hypothetical protein MGC5370 242
419029 AA233397 Hs 326290 hypothetical protein FLJ12581 242
437908 AI082424 ESTs 241
414812 X72755 Hs 77367 monokine induced by gamma interferon 241
425202 AW962282 Hs 152049 ESTs, Weakly similar to I38022 hypotheti 240
425212 AW962253 Hs 171618 ESTs 239
423787 AJ295745 Hs 236204 nuclear pore complex protein 238
425601 AW629485 Hs 140720 GSK-3 binding protein FRAT2 238
449676 AW380579 Hs 209657 ESTs 238
429467 NM 004477 Hs 203772 FSHD region gene 1 237
453227 AW135862 Hs 243991 ESTs 237
417833 AW003251 Hs 86264 hypothetical protein FLJ14549 2 36
451999 AW176401 Hs 27424 DEAD/H (Asp-Glu-Ala-Asp/His) box polypep 236
407910 AA650274 Hs 41296 fibronectin leucine πch transmembrane p 235
418866 T65754 gb yc11c07 s1 Stratagene lung (937210) H 235
410060 NM 001448 Hs 58367 glypican 4 235
449138 AW294215 Hs 195631 ESTs 235
425159 NM 004341 Hs 154868 carbamoyl-phosphate synthetase 2, aspart 235
434808 AF155108 Hs 256150 Homo sapiens, Similar to RIKEN cDNA 2810 235
436481 AA379597 Hs 5199 HSPC150 protein similarto ubiquitin-con 234
410275 U85658 Hε 61796 transcription fxtor AP-2 gamma (xtivat 234
407818 AL021938 Hε 40154 jumoπji (mouεe) homolog 234
417777 AI823763 Hs 7055 ESTs, Weakly similar to I78885 seπne/th 233
401704 NM.021195* Homo sapiens claudin 6 (CLDN6 233
449670 F07693 Hs 85603 Homo sapienε mRNA, cDNA DKFZp434K2172 (f 232
424081 NM 006413 Hs 139120 πbonuclease P (30kD) 2 32
422809 AK001379 Hs 121028 hypothetical protein FU 10549 231
429271 AF039850 Hs 198515 dead ringer (Drosophιla)-lιke 1 230
432865 AI753709 Hs 152484 ESTs, Weakly similar to I38022 hypotheti 230
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 230
410166 AK001376 Hs 59346 hypothetical protein F 10514 230
448755 AW503807 Hs 21907 histone xetyltransferase 230
403433 NM.001622 Homo εapiens alpha-2-HS-glycop 229
441031 AH 10684 Hs 7645 fibnnogen, B beta polypeptide 229
419594 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 2 28
407289 AA135159 Hε 203349 Homo sapieπε cDNA FU12149 fis, clone MA 227
425910 AA830797 Hs 184760 CCAAT-box-binding tranεcnption fxtor 226
401220 branched chain aminotransferase 1, cytos 2 26
453985 N44545 Hs 251865 ESTs 2 25
414890 BE281095 Hε 77573 undine phosphorylase 225
409014 H83115 Hs 49760 origin recognition complex, subunit 6 (y 225
418140 BE613836 Hs 83551 microfibπllar-asεxiated protein 2 225
424765 AA428211 hypothetical protein FU14033 similarto 225
419278 AU076799 Hs 1247 apolipoprotein A-IV 224
412123 BE251328 Hs 73291 hypothetical protein FU10881 224
438459 T49300 Hs 35304 Homo sapiens cDNA FU13655 fis, clone PL 223
417273 AK002209 Hs 81831 Homo sapiens cDNA FU11347 fis, clone PL 223
449722 BE280074 Hs 23960 cyclin B1 2 22
443184 AI638728 Hs 131973 ESTε 222
416391 AI878927 Hs 79284 mesoderm specific transcnpt (mouεe) hom 221
440983 M20681 Hs 7594 εolute earner family 2 (facilitated glu 2 21
435045 BE297155 Hε 143698 ESTε 221
414883 AA926960 CDC28 protein kinaεe 1 221
446323 AI288274 Hs 345792 ESTs 220
410855 X97795 Hs 66718 RAD54 (S cerevιsιae)-lιke 220
448757 AI366784 Hs 48820 TATA box binding protein (TBP)-aεεxιate 220
450254 NM 004885 Hε 99231 neuropeptide G protein-coupled rxeptor, 2 20
418973 AA233056 Hε 191518 ESTε 2 20
413582 AW295647 Hε 71331 hypothetical protein MGC5350 220
434334 AA912476 Hs 116750 Homo εapienε cDNA FU 13221 fiε, clone NT 2 20
443748 AW206447 gb UI-H-BII-afg-g 02-0-UI ε1 NCI CGAP Su 2 20
415989 AI267700 ESTε 220
400195 NM 007057* Homo εapienε ZW10 interactor 220
428878 AA436884 Hs 48926 ESTε 220
431805 NM 014053 Hs 270594 FLVCR protein 219
446839 BE091926 Hs 16244 mitotic spindle coiled-coil related prot 2 19
424381 AA285249 Hs 146329 protein kinase Chk2(CHEK2) 2 18
417389 BE260964 Hs 82045 midkme (neuπte growth promoting factor 2 18 423905 AW579960 Hs 135150 lung type I cell membrane assxiated gly 218
413992 W26276 Hs 104557 RNA, U2 εmall nuclear 2 18
412722 AI343300 Hs 15091 ESTs 218
409089 NM.014781 Hs 50421 KIAA0203 gene product 217
430809 AI791150 Hs 262009 ESTs Moderately similar to I38022 hypot 2 17
406542 C19000728* gι|12585552|sp|Q9Y2Q1 |Z257_HU 217
420509 M83554 Hs 1314 tumor necrosis factor rxeptor superfami 217
425234 AW152225 Hs 165909 ESTs Weakly similar to I38022 hypotheti 2 17
425580 L11144 Hs 1907 galanm 216
439398 AA284267 Hs 221504 ESTs 2 16
452833 BE559681 Hs 30736 KIAA0124 protein 215
421350 AW301608 Hs 278188 ESTs, Moderately similar to I54374 gene 215
444863 AW384082 Hs 104879 seπne (or cyεteine) proteinase inhibito 2 15
449410 AA001356 Hs 18159 ESTs 2 15
442717 R88362 Hs 180591 ESTs, Weakly similar to T23976 hypotheti 215
427953 AA417944 Hs 44331 ESTε 215
422281 M36803 Hs 346935 hemopexm 2 15
433675 AW977653 Hs 75319 πbonucleotide reductaεe M2 polypeptide 214
444960 AI611317 Hs 341531 ESTε 214
415890 H08225 Hs 268712 ESTs 2 14
402099 ENSP00000217725* Laminin alpha 1 chain p 214
427779 AA906997 Hs 180780 TERA protein 214
453005 AW055308 Hs 31803 ESTs, Weakly similar to N-WASP [H sapien 214
422170 AI791949 Hs 112432 anti-Mulleπan hormone 214
414161 AA136106 Hs 184852 KIAA1553 protein 214
437623 D63880 Hs 5719 chromoεome condensation related SMC-asso 2 13
449810 AB008681 Hs 23994 activin A rxeptor, type IIB 211
450663 H43540 Hs 25292 πbonuclease HI, large subunit 211
419525 T79257 Hs 1259 asialoglycoprotem receptor 2 2 11
424727 AW590378 Hs 152519 hypothetical protein FLJ20674 210
418592 X99226 Hs 284153 Fanconi anemia complementation group A 210
425292 NM 005824 Hs 155545 37 kDa leucine-πch repeat (LRR) protein 210
430821 AA487264 Hs 154974 Homo sapiens mRNA cDNA DKFZp667N064 (fr 209
418552 AF198254 Hs 86088 IGF II mRNA binding protein 1 209
408291 AB023191 Hs 44131 KIAA0974 protein 209
425474 Z48054 Hs 158084 peroxisome rxeptor 1 209
453028 AB006532 Hs 31442 RxQ protein like 4 209
447831 AI433293 Hs 164115 ESTs 208
437162 AW005505 Hs 5464 thyroid hormone rxeptor coactivatmg pr 208
429166 AB033096 Hs 197668 KIAA1270 protein 208
432446 AA542845 Hs 294088 GAJ protein 208
417866 AW067903 Hs 82772 collagen, type XI, alpha 1 207
431093 AB031038 Hs 301704 eomesodermin (Xenopus laevis) homolog 207
408116 AA251393 Hs 289052 Homo sapiens, Similar to RIKEN cDNA 5430 207
449569 AI656634 Hs 195389 ESTs 207
429999 AI761902 Hs 99597 ESTs 206
420552 AK000492 Hs 98806 hypothetical protein 206
423175 W27595 Hs 347310 hypothetical protein FU 14627 205
406137 NM.000179* Homo sapiens mutS (E coli) h 205
413833 Z15005 Hs 75573 centromere protein E (312kD) 205
450375 AA009647 a disintegnn and metalloproteinase doma 205
409066 AA062980 Hs 66960 ESTs 205
425700 AF076292 Hs 159251 forkhead box H1 205
432359 AA076049 Hs 274415 Homo sapienε cDNA FLJ10229 fis, clone HE 205
409093 BE243834 Hs 50441 CGI 04 protein 205
418054 NM 002318 Hs 83354 lysyl oxidase-like 2 204
408446 AW450669 Hs 45068 hypothetical protein DKFZp434l143 204
417115 AW952792 Hs 334612 εmall nuclear πboπucleoprotem polypept 204
429840 AA459699 Hs 99496 ESTε 203
409717 AW452871 Hε 56043 CGI-115 protein 202
418113 AI272141 Hε 83484 SRY (εex determining region Y) box 4 202
448275 BE514434 Hε 20830 kinesm like 2 202
432731 R31178 Hs 287820 fibronxtin 1 202
405157 NM_003213* Homo εapieπs TEA domain famil 202
425274 BE281191 Hs 155462 minichromosome maintenance deficient (mi 201
423739 AA398155 Hs 97600 ESTs 201
421310 AW630087 Hs 103315 tπnucleotide repeat containing 1 200
457107 AA418246 Hs 185796 ESTs, Weakly similar to Z184 HUMAN ZING 200
437257 AI283085 Hs 290931 ESTs, Weakly similar to YFJ7.YEAST HYPOT 200
407259 L02256 gb Human Fab fragment binding syncytial 200
TABLE 50B
Pkey Unique Eos probeset identifier number CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT Number Accesεion
432666 144 7 AA558585 AA565499AI360576 AW204069 AA991648 AA864939
423458 30480 1 BC018070 BG702493 AI204212 AA460929 AA993606 BF926635 AA226938 BG190705 BG186496 AW291865 BG183340 BG195301 BG214539
BG215094 BG198867 BG196332 BG208220 BG212418 430676 60836.2 BG433950 BE061583 T05808 BE144813 AW812038 BE144812AW812040AW812041 AU124350 BE061602 BE061604 BF922595 BE061603
AI352469 BE061601 BI062752 AW818206 BF887722
427521 513212.1 AW973352 BF222929 AW016853 BF059130 AI651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 A1206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892
427486 6841591 BF510715 BE673055 BE464111 AW590620 AI637939 AA404324 AW236441 AI650952 BF056796 AA974433
412537 14066.1 AK025201 AA425472 AI694282 BG057305 AA907787 AI286170 AI684577 AJ420494 AI809865 BF058095 AI478773 AH 60445 AL044114
AW665529 AI129239AW297152AI268215AI469807AI969353 BE552356 N66509 AA736741 AA382555 AW075811 AV759188 BI259364
BF445142 BG232065 AH 41758 AI631202 AI167566 AI208445 AA889823 BF982682 N90322 BI090882 BF208005 AW953918 AL044113 AI016793
AA382556 AW235763 AA927051 AI862075 BE886691 BE619282
443068 1869517 AV752763 AI032142 N30308 N22181 H95390 AW675632
436812 6597791 AW978773 AW298067 AA810101 AW194180 AA731645 AI690673
418477 4172.1 BC022538 AI990847 BF478249 BG217996 BG212702 BG182057 AW589883 BF000085 AA993969 BG479023 BG220014 BG679466 BE907092
AI623855 AA223956 AA223917 AW022983 AW090580 AW573219 BF514491 BF445397 AA884705 AI910424
418378 1227421 1 AA218925 AW962081 AA354237
422689 8742091 AW954733 AA315006 AW856665
435514 1322881 AA683356 AW592804 AI150287
439780 490821 AL109688 R23665 R26578
434609 147391 AF147390 R76593 R76594
454679 1743251 AW813110 BF771370 BF771371 AW813113AW003381
434414 35978 T AF134164 BF809407 AA218567 BF842863 AI267168 BF876178 BG999253 AW861851 AW858362 AI817548 BF771300 AA113928 AA223422
AA055556 BF773400 BF998869 BE081333 BE073424 BE142245 H59571 H59570 BF871558 BF871064 BE001132 BF826831 AW754298
AA223267 BG997895 BG997897 AW991957 AA534354 BG319501 BF736309 AI694265 AA045564 BG950256 AI829309 BG987850 BE093175
BF854337
409517 4537.1 NM.000363 X54163 M64247 AI265781 AI760600 AI367238 BE140258 AW207185 AI657074 C03333 AH 93911 C05024 C03193 AI950215 C05070
C05613 W17389 C05351 AA311399 C04180 C04896 C05502 C05482 C04456 C04543 C04558 C04551 C03114 C03103 AI369979 AI652255 T12391 T12073 W19390 C02994 C02730 C04434 W07136 R57607 C03339
406687 00 M31126
457191 13891821 AI216469 AI354789 AA446136 H24336 AA446443 AI376228 R48940
410704 1054673.1 AW877458 AW877524 BE076922 BE166912 AW840534 BE076754 AW797829 BE166905 BE166926 AW877462 BE166927 BE166932 AW877523
BE166917 AW877529 BE166928 BF351394 AW877522 AW877528 BE166861 BE166866 BE166913 BE166919 AW877456 AW877537 BE076866
AW840571
413646 15256561 BE155042 BE155040 BE154987 BE155012
442032 154071 BF223060 BF222818 AI950472 AW016786 AI207136 AI969730 BF222890 AI633857 AI968711 AA974235 AI352637
411022 10666661 AW936378 AW936544 AW813513
429228 215430.1 BG676155 BM009591 AI479075 AI025794 AI017967 AA448270 BE466812 AA853422 AI392649 BG952034 AA513384 BF840124 BE714620
AW969605AI553633
445093 1759631 AI207197 BF773544 AW196462
420218 191547.1 AW958037 R42557 AI337047 AA948360 AI638005 AA459950 AI624915 AI638047 AI467856 AI521826 AA860305 AI932315 AW003092 AW271756
AW779380 AA609879 AI634791 AI493770 AI565211 Z41145 AI627952 AA303734 BE349457 AW196765 AA256527 BE089727
435096 1252151 H30075 AA664977 AW975278
422468 2166741 AW962701 AA310998 AW962699
415684 1869518 BF666746 D59356 BG678312 N56640 AA166861
447350 22673241 AI375572 AI480404 BF430912 T06882
410276 6414431 AA083514 AI554545 AW169852 AI363822 AI633826 AI656026 AI765624 AA147545 AA147552
437908 1326811 AI740586 AA771806 BE500996 AW204531 AI082424 AI033879 BF093176 AA771764 D38676
418866 2459471 T65754 AA229658 AA229857
424765 68571 AK021881 AU145974 AU145787 C16964AA428211 AU119698 AA993264 BF999192AW903017 AA346559AU119446 AW581679 AA991677
AW898165 AW386878 AW890957 Z18340
414883 8371 2 AF274943 BG494894 AI719075 AA908783 AI935150 AI422691 AA910644 AA583187 BM272167 AI828996 AA527373 AW972459 AI831360
AA772418 AI033892 AA100926 AU154749 AI459432 AI423513 AI094597 AA740817 AI991988 AI090262 AI312104 BI256707 AA459522 AA416871
AI075239 AI339996 AA701623 AI139549 AI336880 AA633648 AI989380 AI362835 AA399239 AI146955 BF514270 N92892 AI348243 AI278887
AA459292 AI494230 BF507531 AI492600 AA962596 AW613002 AA293140 AA235549 BF108854 AA954344 N49682 AI457100 AW589407
AW300758 BE220715 BE220698 BE569091 BM009647 BF900351 AI537692 AI203723 AI857576 AA584410 AW371667 BM172363
443748 669881 1 BM467830 AI084433 AW206447 AI400976 AI248530 R16553 415989 10194.1 BC013389 BC017398 AI023543 AA191424 AI267700 AI469633 AW958465 AW953397 AA172056 BE940298 BF909208 BF909980 BF095153
BG285837 AI720344 BF541715 AA355086 AA172236
400195 16894.2 BM477554 BM423967 BC020979 AF067656 NM 007057 BI869291 BG468263 BG760599 BI261788 AA855060 BE257094 BF212452 BE888249
81259219 AW409765 BE089556 AL564377 BI258884 AW440401 AL578460 AL578434 AL556136 BG036804 AL531381 AW371767 BG610641
BF102552 BE294929 BF792282 BG121657 BG502285 BG777493 AL564510 AW770358 AA573448 AA564001 AA969560 AW078946 AW750065
AL573860AA143778 H99221 AA969210 AW103401 AW750073
450375 16559 3 BG570706 BG572749 AW606284 H04021 AA151166 AW954405 AA131254 BG056461 W46291 H01532 H04384 H03231 AA852876 H04410
H59605 BE157601 AA113758
TABLE 50C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495
Strand Indicates DNA strand from which exonε were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
404996 6007890 Plus 37999-38145,38652-38998,39727-39872,4055
406547 7711513 Minus 172780-174358
402145 8018280 Plus 113086-114800
403780 8076989 Plus 9316093409
403432 9719611 Minus 68204-68392
401704 3097841 Plus 24712-25374
403433 9719611 Minus 72225-72437
401220 9929324 Minus 48079-48279
406542 7711499 Plus 117335-118473
402099 8117697 Plus 121553-121742,123265-123423
406137 9166422 Minus 30487-31058 405157 9966228 Plus 156363156502,157573157746
TABLE 51A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Acceεεion number Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of semmomatous testicular cancer compared to normal adult tisεueε
Pkey ExAccn UnigenelD Unigene Title Rl
418696 AW959433 Hε 326290 hypothetical protein FLJ12581 5662
432666 AW204069 ESTs Weakly similar to unnamed protein 4900
432730 AI066520 Hε 131358 ESTs 37 64
426534 U58096 Hs 2051 testis specific protein, Y-lmked 3760
428664 AK001666 Hs 189095 similar to SALL1 (sal (Drosophila) like 3270
420367 AA259090 Hs 257028 ESTs 2998
420347 AL033539 Hs 97124 Human DNA sequence from clone RP1-309H15 2650
437052 AA861697 Hs 120591 ESTs 2642
407710 AW022727 Hs 23616 ESTs 2385
420528 AF130728 Hs 98586 doublesex and mab-3 related transcπptio 23 12
424578 AK001973 Hs 150890 hypothetical protein 2227
420759 T11832 Hs 127797 Homo sapiens cDNA FLJ 11381 fis clone HE 2206
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 2046
429486 AF155827 Hs 203963 hypothetical protein FLJ10339 1844
434649 AA738254 Hs 165390 ESTs, Highly similar to A40350 transcπp 1592
430252 AI638774 Hε 105328 testeε development related NYD SP20 1544
423458 AI204212 ESTε 1528
438915 AA280174 Hs 285681 Williams Beuren syndrome chromosome regi 1526
427711 M31659 Hs 180408 solute earner family 25 (mitochondnal 1484
427667 AK001279 Hs 180171 Homo sapiens cDNA FLJ 10417 fis, clone NT 1298
426427 M86699 Hs 169840 TTK protein kinase 1244
420401 AK001907 Hs 97464 hypothetical protein 1240
406937 U14622 gb Human tranεketolase like protein gene 11 60
430521 NM 016383 Hs 242183 HOM-TES 85 tumor antigen 11 55
425769 U72513 Hs 159486 Human RPL13 2 pseudogene mRNA, complete 11 52
418477 AW022983 gb df46h12 y1 Morton Fetal Cxhlea Homo 1094
434551 BE387162 Hs 280858 ESTs, Highly similar to A35661 DNA excis 1078
436812 AW298067 gb Ul-H BWO-ajp-g 09-0-UI s1 NCI_CGAP_Su 1054
437789 AI581344 Hs 127812 ESTε, Weakly similarto T17330 hypotheti 1040
433800 AI034361 Hs 135150 lung type 1 cell membrane-assxiated gly 1032
421241 X91817 Hs 102866 tranεketolase like 1 10 14
410102 AW248508 Hs 279727 ESTs homologue of PEM-3 [Ciona εavignyi 1002
418134 AA397769 Hs 86617 ESTs 976
433159 AB035898 Hs 150587 kinesm like protein 2 956
433975 AA971953 Hs 122055 ESTs 936
422956 BE545072 Hs 122579 ECT2 protein (Epithelial cell transformi 930
410561 BE540255 Hs 6994 Homo sapiens cDNA FLJ22044 fis, clone H 922
431494 AA991355 Hs 298312 hypothetical protein DKFZp434A1315 9 16
436899 AA764852 ESTs 876
426083 AW962712 Hs 126712 ESTε, Weakly similar to AF191020 1 E2IG5 876
424905 NM 002497 Hs 153704 NIMA (never in mitosis gene a) related k 864
408908 BE296227 Hs 250822 seπne/threoniπe kinase 15 850
413627 BE182082 Hs 246973 intron of Bioaudal D homolog 1 842
425572 AB011076 Hs 158307 undiffereπtiated embryonic cell transcπ 830
415857 AA866115 Hs 127797 Homo sapiens cDMA FU11381 fis, clone HE 814
408728 AL137379 Hs 47125 hypothetical protein FU13912 814
406547 Target Exon 802
424153 AA451737 Hs 141496 MAGE like 2 790
434699 AA643687 Hs 149425 Homo sapienε cDNA FU11980 fiε, clone HE 764
437421 AA917062 ESTs 753
409731 AA125985 Hs 56145 thymosin, beta, identified in neuroblast 7 50
419423 D26488 Hs 90315 KIAA0007 protein 738
428227 AA321649 Hs 2248 εmall inducible cytokine εubfamily B (Cy 738
431840 AA534908 Hs 2860 POU domain, class 5, transcnption fxto 732
430676 AF084866 gb Homo sapiens envelope protein RIC-3 ( 729
436608 AA628980 Hs 192371 down syndrome cπtical region protein DS 725
435206 AI432364 Hs 160594 ESTs 720
414972 BE263782 Hs 77695 KIAA0008 gene product 712
407340 AA810168 Hs 284289 vitiligo-assxiated protein VIT-1 7 10
426518 Z43039 Hs 170198 KIAA0009 gene product 710
436513 AJ278110 Hs 125507 DEAD box protein 704
427521 AW973352 ESTs 696
423673 BE003054 Hs 1695 matnx metalloproteinase 12 (macrophage 692
422232 D43945 Hs 113274 transcnption factor EC 690
420047 AI478658 Hs 94631 brefeld A inhibited guanine nucleotide 683
431041 AA490967 Hs 197955 KIAA0704 protein 676
427335 AA448542 Hs 251677 G antigen 7B 658
422797 AB033064 Hs 236463 KIAA1238 protein 655
418379 AA218940 Hs 137516 fidgetin like 1 646 423905 AW579960 Hs 135150 lung type I cell membrane-assxiated gly 645
433764 AW753676 Hs 39982 zinc finger protein RINZF (NM.023929) 644
422665 AJ011812 Hs 119018 transcnption factor NRF 6 38
433701 AW445023 Hs 15155 ESTs 634
436909 AA907120 ESTε 628
423728 AW891294 Hs 132136 solute carrier family 4 sodium bicarbon 627
429228 AI553633 ESTs 6 26
419384 AA490866 Hs 39429 ESTs 6 23
435514 AW592804 ESTs 608
434334 AA912476 Hs 116750 Homo sapienε cDNA FLJ13221 fis, clone NT 590
430835 AI240006 Hs 192326 ESTε 589
438188 AA779975 Hs 128859 ESTε 588
429120 AK001673 Hε 196530 hypothetical protein FLJ10811 5 80
408758 NM 003686 Hε 47504 exonuclease 1 578
424081 NM 006413 Hε 139120 πbonuclease P (30kD) 570
432359 AA076049 Hs 274415 Homo sapiens cDNA FLJ10229 fis, clone HE 567
428153 AW513143 Hs 98367 SRY (sex determining region Y)-box 17 (S 564
422689 AW856665 gb RC3-CT0297-290100-013-d03 CT0297 Homo 558
428301 AW628666 Hs 98440 ESTs, Weakly similar to I38022 hypotheti 558
419556 U29615 Hs 91093 chitmase 1 (chitotπosidase) 5 55
438494 AA908678 Hs 130183 ESTs 552
421974 AA301270 gb EST14192 Testis tumor Homo sapiens cD 552
427510 Z47542 Hs 179312 small nuclear RNA xtivating complex, po 548
412265 AA101325 Hs 86154 hypothetical protein FLJ 12457 545
413623 AA825721 Hs 246973 intron of Bicaudal D homolog 1 5 36
402145 Target Exon 530
414136 AA812434 SMC2 (structural maintenance of chromoεo 528
428479 Y00272 Hs 334562 cell division cycle 2, G1 to S and G2 to 522
428949 AA442153 Hs 104744 hypothetical protein DKFZp434J0617 5 16
408460 AA054726 Hs 285574 ESTs 514
415947 U04045 Hs 78934 mutS (E coli) homolog 2 (colon cancer, 512
420900 AL045633 Hs 44269 ESTs 508
426496 D31765 Hs 170114 KIAA0061 protein 501
407122 H20276 Hs 31742 ESTs 500
422938 NM.001809 Hs 1594 centromere protein A (17kD) 495
402199 Target Exon 490
409103 AF251237 Hs 112208 XAGE-1 protein 490
416859 H43437 Hs 80305 hypothetical protein MGC14258 484
410166 AK001376 Hs 59346 hypothetical protein FU10514 482
410929 H47233 Hs 30643 ESTε 473
417886 AA214584 ESTε 473
426223 AW977812 Hε 130391 ESTε 472
409421 AA199883 Hε 67624 ESTε 472
428249 AA130914 Hε 183291 zinc finger protein 268 471
429999 AI761902 Hs 99597 ESTε 468
431721 AB032996 Hs 268044 KIAA1170 protein 468
408321 AW405882 Hs 44205 cortiεtatm 467
419197 N48921 Hs 27441 KIAA1615 protein 466
428329 AA426091 Hε 98453 ESTε, Moderately similar to R273282 [H 464
418235 BE072634 gb PM4-BT0548-171299 001-h08 BT0548 Homo 464
427119 AW880562 Hε 272525 ESTs 464
414812 X72755 Hε 77367 monokine induced by gamma interferon 464
414034 U89277 Hε 305985 early development regulator 1 (homolog o 464
409066 AA062980 Hε 66960 ESTs 462
416201 AA467752 Hε 195161 ESTs 453
433330 AW207084 Hs 132816 hypothetical protein MGC14801 452
429629 BE501732 Hs 30622 Homo sapiens cDNA FU13010 fis, clone NT 450
437099 N77793 Hs 48659 ESTs, Highly similarto S14458 laminin a 446
415799 AA653718 Hs 225841 DKFZP434D193 protein 446
412530 AA766268 Hs 266273 hypothetical protein FU 13346 434
418221 Z45514 Hs 83775 DiGeorge syndrome gene D 432
418971 AA360392 Hs 87113 ESTs 430
416111 AA033813 Hs 79018 chromatin asεembly fxtor 1 , subunit A ( 429
423175 W27595 Hs 347310 hypothetical protein FLJ14627 421
415717 AA167270 Hs 130435 ESTs 418
423198 M81933 Hs 1634 cell division cycle 25A 412
433849 BE465884 Hs 280728 ESTs 412
436211 AK001581 Hs 334828 hypothetical protein FLJ10719, KIAA1794 411
432840 AK001403 Hs 279521 hypothetical protein FLJ20530 407
421307 BE539976 Hs 103305 Homo sapiens mRNA, cDNA DKFZp434B0425 (f 407
414725 AA769791 nng finger protein 21, interferon-respo 405
408291 AB023191 Hs 44131 KIAA0974 protem 405
408332 H91230 Hs 234794 Homo sapiens mRNA, cDNA DKFZp564B083 (fr 404
416773 AK000340 Hs 79828 hypothetical protein FU20333 404
427584 BE410293 Hs 179718 v-myb avian myeloblastosis viral oncogen 403
421917 AB028943 Hs 109445 KIAA1020 protem 402
430647 AC003682 Hs 127988 ESTs Weakly similar to Z211 HUMAN ZINC 402
430287 AW182459 Hs 125759 ESTs, Weakly similar to LEU5 HUMAN LEUKE 401
436360 AI962796 Hs 156100 ESTε 400
438624 AA889055 Hs 123468 ESTε 3 99
434609 R76593 gb yι60c11 r1 Soares placenta Nb2HP Homo 392
411945 AL033527 Hs 92137 L-myc 2 proteιn(MYCL2) 390
408065 AW954272 gb EST366342 MAGE resequences, MAGC Homo 390 413833 Z15005 Hs 75573 centromere protein E (312kD) 390
421010 AW974553 Hs 267124 ESTs Weakly similar to ALU6.HUMAN ALU S 388
438456 AA913381 Hs 20594 ESTs 388
424687 J05070 Hs 151738 matrix metalloprotemase 9 (gelatinase B 3 87
412537 AL031778 nuclear transcnption factor Y, alpha 386
418661 NM.001949 Hs 1189 E2F transcription factor 3 385
408750 BE294069 Hs 93581 hypothetical protein FU10512 383
422094 AF129535 Hs 272027 F-box only protein 5 3 82
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet ac 380
416350 AF188625 Hs 189507 phospholipase A2, group IID 378
426054 U12431 Hs 166109 ELAV (embryonic lethal, abnormal vision, 376
401435 C14000397* gι|7499898|pιrl|T33295 hypoth 376
424557 AA343057 Hs 164588 ESTs Moderately similar to neuronal thr 374
422631 BE218919 Hs 118793 hypothetical protein FLJ10688 370
409089 NM.014781 Hs 50421 KIAA0203 gene product 370
426067 AW664691 Hs 97053 ESTs 367
415684 D59356 sorbitol dehydrogenase 3 66
429469 M64590 Hs 27 glycine dehydrogenase (dxarboxylating, 362
424590 AW966399 Hs 46821 hypothetical protein FLJ20086 362
427761 AA412205 Hs 140996 ESTs 361
433641 AF080229 gb Human endogenous retrovirus K clone 1 360
418216 AA662240 Hs 283099 AF15q14 protein 359
438180 AA808189 Hs 272151 ESTs 3 58
424281 AA766243 gb oa13b11 s1 NCI_CGAP_GCB1 Homo sapiens 356
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 355
428878 AA436884 Hs 48926 ESTs 3 54
438885 AI886558 Hs 184987 ESTs 353
416445 AL043004 Hs 79337 KIAA0135 protein 352
424381 AA285249 Hs 146329 protein kinase Chk2(CHEK2) 351
432415 T16971 Hs 289014 ESTs, Weakly similar to A43932 mucin 2 p 349
427298 AA400495 ESTs 348
420218 AW958037 ribosomal protem L4 340
407300 AA102616 Hs 120769 gb zn43e07 s1 Stratagene HeLa cell s393 340
410420 AA224053 Hs 172405 cell division cycle 27 340
432809 AA565509 Hs 131703 ESTs 336
424085 NM.002914 Hs 139226 replication factor C (xtivator 1) 2 (40 334
421373 AA808229 Hs 46677 ESTs 3 34
423354 AB011130 Hs 127436 calcium channel, voltage-dependent, alph 331
418830 BE513731 Hs 88959 hypothetical protein MGC4816 3 30
431077 AI669133 Hs 115660 hypothetical protein FLJ12810 3 30
418049 AA211467 Homo sapiens, Similar to nuclear l∞aliz 326
420949 AA934063 Hs 13836 ESTs, Weakly similar to I38022 hypotheti 3 22
432407 AA221036 Hs 13273 gb zr03f12 r1 Stratagene NT2 neuronal pr 321
434288 AW189075 Hs 116265 fi"bπllm3 320
418295 AW970043 Hs 238039 hypothetical protein FLJ 11090 3 19
429714 BE561801 Hs 2484 T-cell leukemia/lymphoma 1A 317
421350 AW301608 Hs 278188 ESTs, Moderately similar to I54374 gene 317
420161 AI683069 Hs 120817 ESTs 3 17
414618 AI204600 Hs 96978 hypothetical protein MGG10764 316
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 3 14
414747 U30872 Hs 77204 centromere protein F (350/400kD, mitosm 314
423419 R55336 Hs 23539 ESTs 3 13
410275 U85658 Hs 61796 transcnption fxtor AP-2 gamma (xtivat 3 12
408092 NM 007057 Hs 42650 ZW10 interactor 312
423685 BE350494 Hs 49753 uveal autoantigen with coiled coil domai 312
438378 AW970529 Hs 86434 hypothetical protein FU21816 312
415912 H08859 Hs 206469 ESTs, Weakly similar to ALU6_HUMAN ALU S 312
412140 AA219691 Hs 73625 RAB6 interxting, kinesm like (rabkmes 3 11
420552 AK000492 Hs 98806 hypothetical protein 311
402408 NMJ330920* Homo sapiens hypothetical pro 3 10
432281 AK001239 Hs 274263 hypothetical protein FLJ10377 3 10
415829 AW450198 Hs 163742 ESTs 309
423739 AA398155 Hs 97600 ESTs 307
418459 R85436 Hs 268814 ESTs 307
421972 M18185 Hs 1454 gastπc inhibitory polypeptide 307
437257 AI283085 Hs 290931 ESTs, Weakly similar to YFJ7 YEAST HYPOT 306
429830 AI537278 Hs 225841 DKFZP434D193 protein 306
420524 AB010575 Hs 98547 amiloπde-senεitive cation channel 3, te 306
433023 AW864793 thrombospondm 1 304
421633 AF121860 Hs 106260 sorting nexm 10 304
420507 AF093408 Hs 98397 A kinase (PRKA) anchor protein 3 304
432938 T27013 Hs 3132 steroidogenic xute regulatory protein 303
414598 AI094221 Hs 135150 lung type I cell membrane-aεsxiated gly 303
419635 NM.005033 Hs 91728 polymyositiε/εcleroderma autoantigen 1 ( 3 03
425312 AA354940 Hs 145958 ESTε 302
425474 Z48054 Hs 158084 peroxisome rxeptor 1 301
411027 AF072099 Hs 67846 leukxyte immunoglobulin like rxeptor, 301
432446 AA542845 Hs 294088 GAJ protein 301
424513 BE385864 Hs 149894 mitochondnal translational initiation f 300
436902 AW247145 Hs 192729 ESTs 300
422789 AK001113 Hs 120842 hypothetical protein FLJ10251 300
430056 X97548 Hs 228059 KRAB assxiated protein 1 2 98
427617 D42063 Hs 199179 RAN binding protein 2 298 406367 NM 022357 Homo sapiens putative metallop 297
418866 T65754 gb yd 1c07 s1 Stratagene lung (937210) H 297
435918 AF263538 Hs 86232 growth differentiation factor 3 297
436511 AA721252 Hs 291502 ESTs 296
402680 Target Exon 296
414161 AA136106 Hs 184852 KIAA1553 protein 295
427239 BE270447 ubiquitin carrier protein 295
433683 AI817723 Hs 22678 hypothetical protein FLJ21832 294
417576 AA339449 Hs 82285 phosphoπboεylglycinamide formyltranεfer 294
402299 Target Exon 292
420697 AA827705 Hs 26605 ESTs 290
427719 AI393122 Hs 134726 ESTs 290
419131 AA406293 Hs 109526 ESTs 2 89
410048 W76467 Hs 343874 proline oxidase homolog 289
427314 AB033024 Hs 175475 KIAA1198 protein 289
424315 AW614850 Hs 193384 putatative 28 kDa protein 2 88
430335 D80007 Hs 239499 KIAA0185 protein 287
410361 BE391804 Hs 62661 guanylate binding protein 1, interferon- 287
413686 AI469213 Hs 71404 ESTs 287
429183 AB014604 Hs 197955 KIAA0704 protein 286
430292 AK000634 Hs 238270 hypothetical protein FLJ20627 2 86
422726 U11690 Hs 1572 faciogenital dysplasia (Aarskog-Scott εy 286
437834 AA769294 gb nz36g03 s1 NCI.CGAP.GCB1 Homo sapieπε 286
435159 AA668879 Hs 116649 ESTs 284
428361 NM.015905 Hε 183858 transcriptional intermediary factor 1 284
430388 AA356923 Hs 240770 nuclear cap binding protein subunit 2, 2 284
434070 AF116652 Hs 270087 hypothetical protein PRO0813 283
429323 NM.001649 Hs 2391 apical protein, Xenopus laevis-like 283
433247 AB040948 Hs 142856 KIAA1515 protein 282
415884 H22966 Hs 13471 ESTs 282
427668 AA298760 Hs 180191 hypothetical protein FLJ14904 282
437162 AW005505 Hs 5464 thyroid hormone rxeptor coactivatmg pr 281
401091 dxay xcelerat g factor for complement 281
425601 AW629485 Hs 140720 GSK-3 binding protein FRAT2 279
428597 AK000147 Hs 295909 hypothetical protein FLJ 10700 279
417705 AW134952 Hs 175220 hypothetical protein FLJ14541 279
438243 AI581311 ESTs 278
418203 X54942 Hs 83758 CDC28 protein kinase 2 278
410704 BE076754 gb CM1 BT0601-180200-121-b10 BT0601 Homo 277
429063 AW363845 Hs 322903 ESTs Weakly similar to A46010 X-lmked 276
427147 AA398587 Hs 97414 ESTs 276
430552 AA176374 Hs 243886 nuclear autoantigenic sperm protein (his 276
437660 W31708 Hs 55304 ESTs 274
425237 U07695 Hs 155227 EphB4 272
419335 AW960146 Hs 284137 hypothetical protein FLJ12888 272
426386 AA748850 Hs 125830 bladder cancer overexpresεed protein 270
423123 NM 012247 Hs 124027 SELENOPHOSPHATE SYNTHETASE , Human εelen 270
430968 AW972830 gb EST384925 MAGE reεequenceε, MAGL Homo 270
420596 NM.002692 Hs 99185 polymeraεe (DNA directed), epsilon 2 268
419741 NM.007019 Hs 93002 ubiquitin earner protem E2-C 268
401464 histone dexetylase 5 268
411856 H67899 Hs 4190 Homo sapiens cDNA FLJ23269 fis, clone C 268
411365 M76477 Hs 289082 GM2 gaπglioside xtivator protein 268
419029 AA233397 Hs 326290 hypothetical protein FLJ12581 267
421654 AW163267 Hs 106469 suppressor of varl (S cerevisiae) 3-lιke 266
421535 AB002359 Hs 105478 phosphoπbosylformylglycmamidiπe εyntha 266
423453 AW450737 Hs 128791 CGI 09 protein 266
412673 AL042957 Hs 31845 ESTε 265
410006 AW732308 Hs 57783 eukaryotic translation initiation factor 265
434159 AW135214 Hs 191828 ESTs 265
427260 AA663848 gb ae70b06 s1 Stratagene schizo brain S1 264
439053 BE244588 Hs 6456 chaperonin containing TCP1, subunit 2 (b 264
414706 AW340125 Hs 76989 KIAA0097 gene product 264
433979 AA620999 gb ag03a08 s1 Soareε.teεtiε.NHT Homo sap 264
403969 ENSP00000034663 Zinc finger protein 131 264
420582 BE047878 Hs 99093 Homo sapienε chromosome 19, cosmid R2837 264
418355 L42563 Hs 1165 ATPase, H? transporting, nongastnc, alp 263
411127 AA668995 Hε 218329 hypothetical protein 262
437205 AL110232 Hε 279243 Homo sapiens mRNA, cDNA DKFZp564D2071 (f 262
412123 BE251328 Hε 73291 hypothetical protein FLJ10881 261
436481 AA379597 Hs 5199 HSPC150 protein similarto ubiquitin-con 260
408446 AW450669 Hε 45068 hypothetical protein DKFZp434H43 259
437033 AW248364 Hs 5409 RNA polymerase I subunit 258
418592 X99226 Hs 284153 Fanconi anemia, complementation group A 258
415585 R59946 Hs 184852 KIAA1553 protein 257
424800 AL035588 Hs 153203 MyoD family inhibitor 257
426470 AA528794 Hs 128644 ESTs 257
426919 AL041228 ELAV (embryonic lethal, abnormal vision, 256
421209 AJ010230 Hs 102576 ret finger protein like 1 antiεense 256
437496 AA452378 Hs 146668 Homo sapiens mRNA, cDNA DKFZp547J125 (fr 256
401837 NM 025109 Homo sapiens hypothetical prot 256
428743 AL080060 Hs 301549 Homo sapienε mRNA, cDNA DKFZp564H172 (fr 256
422809 AK001379 Hs 121028 i hypothetical protein FU 10549 255 418648 AW979223 Hs 292478 ESTs 2 55
423020 AA383092 Hs 1608 replication protein A3 (14kD) 2 54
430345 AK000282 Hs 239681 hypothetical protein FLJ20275 254
424075 AI807320 Hs 227630 RE1 silencing transcription factor 254
428728 NM.016625 Hs 191381 hypothetical protein 253
423755 AB037735 Hs 132560 hypothetical protein FLJ10312 252
424051 AL110203 Hs 138411 Homo sapienε mRNA cDNA DKFZp586J1922 (f 252
416734 H81213 Hs 14825 ESTs, Weakly similar to KIAA1503 protein 252
422406 AF025441 Hs 116206 Opa interacting protein 5 2 52
433228 F28212 Hs 14953 KIAA1491 protein 2 51
411943 BE502436 Hs 7962 ESTs, Weakly similar to S44608 C02F56 p 251
426181 AA371422 Hs 334371 hypothetical protein MGC13096 250
423642 AW452650 Hs 157148 hypothetical protein MGC13204 250
411571 AA122393 Hs 70811 hypothetical protein FU20516 248
419750 AL079741 Hs 183114 Homo sapienε cDNA FU 14236 fis, clone NT 248
408209 NM 004454 Hs 43697 ets variant gene 5 (ets related molecule 247
435726 BE535787 Hs 113170 ESTs 247
404068 Target Exon 246
403137 NM_005381* Homo sapiens nucleolin (NCL), 246
434276 AF123659 Hs 93605 leucine zipper, putative tumor suppreεso 246
422283 AW411307 Hs 114311 CDC45 (cell division cycle 45, S cerevis 246
429652 AA766810 Hs 259290 ESTε 245
416204 AW972270 Hs 195161 ESTε 245
414713 BE465243 Hs 12664 ESTs 244
425910 AA830797 Hs 184760 CCAAT-box binding transcnption factor 244
408875 NM 015434 Hs 48604 DKFZP434B168 protein 244
435244 N77221 Hs 187824 ESTs 244
402679 NM.000478 Homo sapiens alkaline phosphat 243
413943 AW294416 Hs 144687 Homo εapienε cDNA FLJ12981 fiε, clone NT 242
433914 AF108138 Hs 112160 Homo εapieπs DNA helicase homolog (PIF1) 241
437812 AI582291 Hs 16846 ESTε, Weakly similar to 04HUD1 debπsoqu 241
410855 X97795 Hs 66718 RAD54 (S cerevisiae) like 241
423232 BE244625 Hs 125742 leucine πch neuronal protein 240
427578 AI591305 Hs 169084 ESTs, Highly similar to TUL3.HUMAN TUBBY 240
409934 R91601 Hs 190466 hypothetical protein FU22584 239
423787 AJ295745 Hs 236204 nuclear pore complex protein 239
420892 AW975076 Hs 172589 nuclear phosphoprotein similar to S cer 239
438869 AF075009 gb Homo sapiens full length insert cDNA 238
434981 AW182577 Hs 293077 ESTs 238
417911 AA333387 Hs 82916 chaperonin containing TCP1 , subunit 6A ( 238
409210 AA251812 Hs 51120 cathelicid antimicrobial peptide 237
424425 AB031480 Hs 146824 SPR1 protein 2 37
411885 AA452636 Hs 131057 ESTs, Moderately similarto CRGD.HUMAN G 237
421567 AJ272137 Hs 198265 matrix metalloproteinaεe 25 237
425159 NM 004341 Hs 154868 carbamoyl phoεphale synthetase 2, aspart 237
418678 NM 001327 Hs 167379 caπcer/testis antigen (NY-ESO-1) 236
431197 AL038596 Hs 250745 polymerase (RNA) III (DNA directed) (62k 236
411630 U42349 Hs 71119 Putative proεtate cancer tumor εuppreεεo 236
410968 AA199907 Hs 67397 ho x box A1 236
421305 BE397354 Hs 324830 diptheria toxin reεiεtaπce protein requi 236
417153 X57010 Hs 81343 collagen, type II, alpha 1 (primary oste 236
412389 AW947655 gb RCO MT0003-140300-031-b07 MT0003 Homo 2 35
419359 AL043202 Hs 90073 chromosome segregation 1 (yeast homolog) 235
403780 C4001759 gι|133250|sp[P19474|RO52_HUMAN 234
437681 AI207958 Hs 166556 Homo sapiens, Similar to TEA domain fami 234
400205 NM_006265* Homo sapienε RAD21 (S pombe) 234
433160 AW207002 Hs 134342 TASP for testis-spxific adπamycin sens 234
432606 NM.002104 Hs 3066 granzyme K (seπne protease, granzyme 3, 234
425331 AW962128 gb EST374201 MAGE reεequences, MAGG Homo 233
430606 BE266026 Hs 31476 Homo εapienε cDNA FLJ13872 fis, clone TH 233
424308 AW975531 Hs 154443 minichromosome maintenance deficient (S 232
418821 AA436002 Hs 183161 ESTs 232
437437 AA226869 hypothetical protein DKFZp762L0311 232
413437 BE313164 Hs 75361 gene from NF2/meπιngtoma region of 22q12 231
425848 BE242709 Hs 159637 valyl tRNA synthetase 2 230
435532 AW291488 Hs 117305 Homo sapiens, clone IMAGE 3682908 mRNA 230
430183 BE010038 gb PM3-BN0176-100400001-g04 BN0176 Homo 230
409342 AU077058 Hs 54089 BRCA1 assxiated RING domain 1 229
430504 H52761 Homo sapienε, clone MGC 12617, mRNA com 229
427726 AI359144 Hs 143688 Homo εapiens cDNA FU23031 fis, clone L 229
417115 AW952792 Hs 334612 small nuclear nbonucleoprotein polypept 228
412721 AW183165 Hs 95600 ESTs 228
404071 C12000514* gι|7302471|gb|AAF57556 1| (AE 227
413762 AW411479 Hs 848 FK506-bmdιng protein 4 (59kD) 226
425811 AL039104 Hs 159557 karyophenn alpha 2 (RAG cohort 1, impor 226
424935 AI655010 Hs 120363 hypothetical protein MGC15634 226
415791 H09366 Hs 78853 urxil DNA glycosylaεe 226
431667 AA812573 Hs 246787 ESTε 226
424169 AA336399 Hs 153797 ESTε 225
436540 BE397032 Hs 14468 hypothetical protein MGC14226 225
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 224
403242 Target Exon 224
414732 AW410976 Hs 77152 minichromosome maintenance deficient (S 224 421002 AF116030 Hs 100932 transcription factor 17 224
438833 BE612940 Hs 88252 ESTs 224
420333 AJ001383 Hs 97084 lymphxyte antigen 94 (mouse) homolog (a 223
433844 AA610175 Hs 179647 Homo sapiens cDNA FLJ12195 fis, clone MA 223
427528 AU077143 Hs 179565 minichromosome maintenance deficient (S 223
430289 AK001952 Hs 238039 hypothetical protein FLJ 11090 223
421016 AA504583 Hs 101047 transcription factor 3 (E2A immunoglobul 223
436251 BE515065 Hs 296585 nucleolar protein (KKE/D repeat) 223
418826 AK000375 Hs 88820 HDCMC28P protein 223
428612 AA770001 ESTs 2.22
433220 AI076192 Hε 131933 ESTs 222
422225 BE245652 Hε 118281 zinc finger protein 266 222
437549 AA759149 Hε 128757 gb ah70e03 s1 Soareε.teεtiε.NHT Homo εap 2 22
409299 AA045650 Hε 53125 εmall nuclear πbonucleoprotein D2 polyp 222
408665 T88845 Hε 112200 ESTε, Weakly similar to ALU7.HUMAN ALU S 222
408116 AA251393 Hs 289052 Homo sapieπε, Similar to RIKEN cDNA 5430 221
420062 AW411096 Hs 94785 TGF(beta) induced transcription fxtor 2 221
432820 AI554057 Hs 152477 ESTs 221
430255 AK000703 Hs 323822 Homo sapienε mRNA for KIAA1551 protein, 2 21
420337 AW295840 Hs 14555 Homo εapiens cDNA FLJ21513 fis, clone C 220
407275 AI364186 gb qw34h07 x1 NCI_CGAP_Ut4 Homo sapiens 220
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient, yeast, h 220
423675 AI990509 Hs 131342 small inducible cytokine subfamily A (Cy 220
433698 H24201 Hs 247423 adducin 2 (beta) 219
409101 NM.004297 Hs 50612 guanine nucleotide binding protein (G pr 219
435541 AA687361 Hs 221318 ESTs 219
412019 AA485890 Hs 69330 Homo sapiens cDNA FU13835 fis, clone TH 219
418753 BE217818 Hs 87016 hypothetical protein FLJ22938 219
435461 AI075846 Hs 133996 ESTs 219
402260 NM 001436* Homo sapiens fibπllaπn (FBL 218
421098 AI697901 Hs 192425 ESTs 218
400587 Cl 0000649* gι|7296574|gb|AAF51857 1| (AE 218
407832 AW976516 Hs 283707 Homo sapienε cDNA FU21354 fiε, clone C 218
427159 U80735 Hs 173854 PAX transcnption activation domain inte 217
405770 NM 002362 Homo sapiens melanoma antigen, 2 17
412722 AI343300 Hs 15091 ESTs 216
414334 AA824298 Hs 21331 hypothetical protein FLJ10036 216
438192 AI859065 Hs 293807 Homo sapienε AFG3L1 isoform 1 mRNA, part 216
417420 T85150 Hs 268814 ESTε 216
421308 AA687322 Hs 192843 leucine zipper protein FKSG14 216
412851 AI826502 Hs 97269 ESTs 216
414702 L22005 Hs 76932 cell division cycle 34 216
409670 AI368109 KIAA1856 protein 216
419926 AW900992 Hs 93796 DKFZP586D2223 protein 215
417863 AB000450 Hs 82771 vxcmia related kinaεe 2 215
434750 BE019254 Hs 4112 t-complex 1 215
410252 AW821182 Hs 61418 microfibnllar-aεεxiated protein 1 215
418574 N28754 M-phaεe phosphoprotein 9 215
409019 AW385412 myosin regulatory light chain 2, smooth 215
416608 R11499 Hs 189716 ESTs ' 214
436027 AI864053 Hs 39972 ESTs, Weakly similar to I38588 reverse t 214
408161 AW952912 Hs 300383 hypothetical protein MGC3032 2 13
422805 AA436989 Hs 121017 H2A histone family, member A 213
410284 U50939 Hs 61828 amyloid beta prxursor protein-binding p 213
434274 AA628539 Hε 116252 ESTs, Moderately similar to ALULHUMAN A 212
430935 AW072916 zinc finger protein 131 (clone pHZ-10) 212
433252 AB040957 Hε 151343 KIAA1524 protein 212
416819 U77735 Hs 80205 pιm-2 oncogene 212
437218 AL117497 Hs 58185 ESTs, Weakly similar to T42727 prolifera 212
407239 AA076350 Hs 67846 leukxyte immunoglobulin-like rxeptor, 212
433947 AA927996 Hs 112876 ESTs, Weakly similar to AF129535 1 F-box 211
424727 AW590378 Hs 152519 hypothetical protein FU20674 211
435703 AW630133 Hs 83313 GK003 protein 211
420297 AI628272 Hs 88323 ESTs, Weakly similar to ALU1.HUMAN ALU S 211
422192 AA305159 Hs 113019 fls485 211
407961 AW672939 Hs 41694 ongm recognition complex, subunit 2 (y 210
410193 AJ132592 Hs 59757 zinc finger protein 281 210
414151 AW976468 Hs 257245 ESTs 210
434789 AW292515 Hs 194317 ESTs, Weakly similar to T08680 hypotheti 210
424196 AL133660 Hs 142926 Homo sapienε beta cysteine stππg protei 210
408831 AF090114 Hs 48433 endocπne regulator 210
414733 BE514535 Hs 77171 minichromosome maintenance deficient (S 209
434523 AA703709 Hs 23410 translxase of inner mitxhoπdπal membr 209
409637 AA323948 Hs 55407 Homo sapiens mRNA, cDNA DKFZp434K0621 (f 209
403532 NM_024638 Homo sapienε hypothetical prot 209
432141 BE410964 Hs 272736 nuclear rxeptor binding protein 208
409014 H83115 Hs 49760 origin recognition complex, εubunit 6 (y 208
410575 BE207480 Hs 6994 Homo εapieπε cDNA FLJ22044 fiε, clone H 208
415071 AK002197 Hε 284270 Homo εapienε cDNA FU11335 fis, clone PL 208
418755 Y14443 Hε 88219 zinc finger protein 200 208
406137 NM.000179* Homo sapiens mutS (E coli) h 207
409893 AW247090 Hs 57101 minichromosome maintenance deficient (S 207
421413 AI826128 Hs 55209 ESTs, Weakly similar to A4936459 protei 207 434283 AW235341 Hε 58715 thiamine pyrophosphokiπase 207
417230 U40998 Hε 81728 unc119 (C elegans) homolog 207
425966 NM 001761 Hε 1973 cyclin F 207
431393 AW971493 Hε 134269 ESTs, Highly similar to cytokine recepto 206
407162 N63855 Hε 142634 zinc finger protein 206
422382 D79988 Hs 115778 KIAA0166 gene product 206
402677 NM_000478 Homo sapiens alkaline phosphat 206
433017 Y15067 Hs 279914 zinc finger protein 232 205
424677 U09414 zinc finger protein 137 (clone pHZ-30) 205
418883 BE387036 Hs 1211 xid phosphatase 5, tartrate resistant 205
424959 NM_005781 Hs 153937 xtivated p21cdc42Hs kinase 205
402678 Target Exon 205
408146 R45621 Hs 81057 hypothetical protein MGC2718 205
420027 AF009746 Hs 94395 ATP-bindmg cassette, sub-family D (ALD) 204
427447 T65414 Hs 6647 Homo sapiens cDNA FU13088 fis, clone NT 204
433219 AB040916 Hs 24106 KIAA1483 protein 204
431126 AF085243 Hs 283619 zinc finger protein 236 204
407136 T64896 Hs 287420 Homo sapiens cDNA FU11533 fis, clone HE 204
419669 AJ007041 Hs 92236 KIAA0304 gene product 204
419594 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 203
426242 AL096727 Hs 168249 Homo sapiens mRNA, cDNA DKFZp434B104 (fr 202
432185 AA221032 Hs 272838 hypothetical protein FLJ10494 202
437108 AA434054 Hs 80624 hypothetical protein MGC2560 202
408636 BE294925 Hs 46680 CGI-12 protein 2 02
420005 AW271106 Hs 133294 ESTs 202
412783 BE276738 Hs 74578 DEAD/H (Asp-Glu-Ala-Aεp/Hiε) box polypep 202
415319 AA659823 Hs 34955 Homo sapiens cDNA FU13485 fis, clone PL 202
425358 AL079658 Hs 338207 FK506 binding protein 12-rapamycιn aεsx 201
409617 BE003760 Hs 55209 Homo εapienε mRNA, cDNA DKFZp434K0514 (f 201
438450 AI050866 Hs 65853 nodal, mouse, homolog 200
431629 AU077025 Hs 265827 interferon, alpha-inducible protein ( o 200
424934 U75370 Hs 153880 polymerase (RNA) mitochondnal (DNA dire 200
436291 BE568452 Hε 344037 protein regulator of cytokmeεiε 1 200
414251 AL042306 Hs 97689 VASA protein 200
TABLE 51 B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank accesεion numberε
Pkey CAT Number Acceεεion
432666 144 7 AA558585 AA565499 AI360576 AW204069 AA991648 AA864939 423458 30480.1 BC018070 BG702493 AI204212 AA460929 AA993606 BF926635 AA226938 BG190705 BG186496 AW291865 BG183340 BG195301 BG214539
BG215094 BG198867 BG196332 BG208220 BG212418
418477 4172.1 BC022538 AI990847 BF478249 BG217996 BG212702 BG182057 AW589883 BF000085 AA993969 BG479023 BG220014 BG679466 BE907092
AI623855 AA223956 AA223917 AW022983 AW090580 AW573219 BF514491 BF445397 AA884705 AI910424
436812 659779 1 AW978773 AW298067 AA810101 AW194180 AA731645 AI690673 436899 1000797.1 AA764852 AA736937 437421 978554 1 AA917062 AA757369AW592218 430676 60836.2 BG433950 BE061583 T05808 BE144813 AW812038 BE144812 AW812040 AW812041 AU124350 BE061602 BE061604 BF922595 BE061603
AI352469 BE061601 BI062752 AW818206 BF887722
427521 513212.1 AW973352 BF222929 AW016853 BF059130 AI651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 AI206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892
436909 596835 1 AW102570 AA907150 AA907120 AA737188 AI248890 AW977353 429228 215430.1 BG676155 BM009591 A1479075 AI025794 A1017967 AA448270 BE466812AA853422 AI392649 BG952034AA513384 BF840124 BE714620
AW969605AI553633
435514 132288 1 AA683356 AW592804 AI150287 4226B9 874209 1 AW954733 AA315006 AW856665 421974 864120 1 AA301270AA301379 AA301366 414136 30243.1 AJ420453 AL526740 AW968449 AA459140 AA843893 AI566516 AW971760 AA430089 AI753216 AA854268 AA743075 AI864957 AA458920
AI566634 AA211796 BG615512 BE169275 BF983253 BF969462 AA766261 AI769894 AA135833 AI831542 N63376 AA214392 AU154486
AW605017AW450072AA446459 BE881875AI061423 AA598549 AW439151 AA426273 Z40087 AA812434AA135965 H04812
417886 1031334 1 AA210987 D57294 AA214584 AA207006 D56572 418235 886897 T BE072634 BE072653 AA830615 AA214736 AA331718 414725 19377.1 NM 058166 AF220030 AL043894 AW974257 AA625445 AU153502 AI650537 AW612116 AI672377 AW772451 BE892241 BE501740 AA718936
AI650276 AI654206 BE503226 AI651327 AW873562 AW271269 AW271565 AI873518 AI207150 AI338826 AI650258 AI628362 AA227117 AI207149
AW052076 AI470776 AA588100 AW235852 AA769791 AI701653 AK027664 AI984770 AU153469 BE222316 AA609539 BE220093 AA609112
BI054316
434609 14739 1 AF147390 R76593 R76594 408065 101881 1 BI603077 AW954272 BI598724 AI003154 AA059300 AA046911 BI669907 BI600966 BI669987 412537 14066.T AK025201 AA425472 AI694282 BG057305 AA907787 AI286170 AI684577 AJ420494 AI809865 BF058095 AI478773 AI160445 AL044114
AW665529 AI129239 AW297152 AI268215 AI469807 AI969353 BE552356 N66509 AA736741 AA382555 AW075811 AV759188 BI259364
BF445142 BG232065 AI141758AI631202 AI167566 AI208445AA889823 BF982682 N90322 BI090882 BF208005AW953918AL044113 AI016793
AA382556 AW235763 AA927051 AI862075 BE886691 BE619282
415684 18695 18 BF666746 D59356 BG678312 N56640 AA166861 433641 35983.1 AF080229 AF080232 U87593 U87592 U87591 U87590 AI636743 AI633818 AW206802 AI583718 AF080231 AF080234 AF080233 AL535594
AI818326 AF080230 S46404 AI970376 AA463992 AW665466 BF512210 U87595 U87589 BE550633 AI672574 BE467547 AI680833 AW614951
N29986 N25695 H69001 U87596 BE673974 AI797496 AI701526 AA703396 AW139734 H92278 N66048 BE219539 BE671665 AI624817 BE466611
AI206344AA574397 BF593413 BG231271 BF773517 U87594 BF062180 BE466420 AI887798 BF674385AA204735 AW496808 AA204833
AA207155 BI004756 AA206262 AI365204 H77608 AW590511
424281 892055.1 AA338252 AA338213 427298 115241 1 AA933717 BF061897 AW628327 AA641788 AA400495 420218 191547.1 AW958037 R42557 AI337047 AA948360 AI638005 AA459950 AI624915 AI638047 AI467856 AI521826 AA860305 AI932315 AW003092 AW271756
AW779380 AA609879 AI634791 AI493770 AI565211 Z41145 AI627952 AA303734 BE349457 AW196765 AA256527 BE089727
418049 12052.4 AJ314647 NM.052888 BI494693 AA835065 AI634477 AI336678 AI807696 BF477887 AI701147 Z39187 R38979 F02234 AA984711 BI222234
AV731417 R42406 H04996 T98498 R12489 R12577 R42405
433023 3970.8 BE999967 BF438599 AW864793 AI802899 BE815132 AW468888 AI672189 AI052004 BF112024 AA772335 AW275054 AA573845 AI144148
AI968683 AA846676 AA927355 H80424 AW973295 R88209 F29868 BE928871
418866 2459471 T65754 AA229658 AA229857 427239 20459.2 AL532360 BE794750 AA582906 AI015067 AW271034 BG271636 AW075177 AW071374 AI345565 AI307208 BE138953 BE049086 AI334881
AW075006 AW075181 AA464019 AW302733 AW075100 AW073433 AI802854 AI334909 AI802853 AI345036 AI348921 AI340734 AI307478
AI251289 AW302327 AW072520 AI312145 AW073656 AW072513 AW071289 AI307559 AA876186 T29587 AI307493 AI255068 AI252868 AI252839
AW074809 AI252926 AI252160 AI251662 AI251262 AI610913 AI270787 AI270156 A1252075 AW073469 AW072901 AW072496 AW071420
AI305762 AI254764 AI802837 AI251264 AW073049 AW071311 AI340643 BE138965 BE138502 AW073456 AI334733 AI054335 BE139260
AI054302 AI054060 AI054057 AI053722 AI289711 BE139228 AW470478 AW271039 AW302085 BE041872 AI254494 AI271496 AI252427
BF718773 BF718645 AW074866 BE857822
437834 294580.1 BG110129 AW749287 BE535498 AW749299 AW749293 AW749302 AW749298 AW749291 AW749294 AW749289 AW749288 AW749296
AA769294 AW749297 AW749295 AW749292 BE002573
438243 2532601.1 AI581311 AA781682 AA781678 410704 1054673.1 AW877458AW877524 BE076922 BE166912AW840534 BE076754AW797829 BE166905 BE166926 AW877462 BE166927 BE166932 AW877523
BE166917 AW877529 BE166928 BF351394 AW877522 AW877528 BE166861 BE166866 BE166913 BE166919 AW877456 AW877537 BE076866
AW840571
430968 1237115.1 AW972830 AA489820 AA527647 AA570362 427260 11272.50 AA401424 AA400100 AA663848 433979 2076469.1 N50454AA620999 T16375 426919 347372.1 BI917595 A1203314AL041228 AV727959 D61361 D82004 BI753157 AA961066 AI990307 BF439651 AI453076 A1376075 AI014836 AI018308
AW183530 AA393346 AA935601 AA628633 AI150282 AI028574 AI217182 AA431478 AW087473 AW900295 H50055 AL041229 BI917726
438869 52134.1 AF075009 R63109 R63068 412389 1174403.1 AW947655 AW984020 400205 2538 1 NM.006265 D38551 X98294 BM477931 BM461566 AU123557 AU133303 AU134649 AW500421 BM172439 AW500587 AW503665 AW504355
AW503640 BM152454 AW505260 AI815984 AW504075 AW500716 AL597310 BC001229 BM474371 AA984202 AU135205 BE090841 AW163750
BF747730 BF898637 AI206506 AV660870 AV692110 AW386830 AV656831 N84710 AW993470 BF086802 BF758454 BG960772 BF757769
BI870853 BE018627 C75436 AW148744 BF757753 BG622067 BE909924 AA708208 BG530266 BF968015 AW992930 BF888862 BG536628
AA143164 AW748953 BG498922 BF885190 BF889005 BF754781 BF800003 BM476529 AI627668 AW028126 AL046011 BF590668 AI017447
AA579936 AI367597 AA699622 BE280597 AH 24620 AI082548 AW274985 AA677870 AI056767 BE551689 AA287642 H94499 AI752427 AI652365
AW002374 AW062651 AA360834 N68822 AU135442 AU125960 Z78334 BE545813 AI092115 BF312771 BF242859 BG533616 BG533761
BG164745 BG492433 BM473183AA172043AA172069AU157092 AU151353 AU155318 BE302211 AI375022 AA085641 AU157923 H88858
AA132730 AA115113 AA909781 AI475256 AA424206 AW572383 AW084296 AI184820 AI469178 AA782432 H92184 AA340562 BF195818
AA852821 AW576342 AA827107 AA173317 AW190014 AI918514 AA729372 AA729718 AI055958 AA331424 BE328601 AA515690 BI018896
AW628277 AA748368 AA626222 BG492636 AW380620 BF800058 AW370956 AA290909 R25857 BG952995 BF801437 AA172077 AU155890
AU149783 AI720904 AA902936 AA865727 AI470830 AV740677 AA142982 AA482485 AU145485 AW576399 AU156042 R63448 BF246427
BE928472 D25910 BF758439 BF968785 BE565238 AA355981 AI905607 BG291148 BG533096 BG532888 BF030886 BG613756 BE928471
BG574501 AA187596 AA361196 T95557 BG531446 BG527242 BG527513 BG611106 AA085995 BF847252 BG024608 BE540261 BG531236
AL579993 BG108733 BG483503 BG571032 BG492505
425331 1227464.1 AA427363 AW962128 AA355353 437437 6087.1 BC009352 BC014630 AU131857 AL527140 AU131768 BI769362 BI753220 AU129886 AU128771 AA314135 AU126819 AI333799 AA479336
AA258503 AL597351 AL359619 BG697218 BI254283 AI743846 AA236444 AA397533 AA247450 AI051464 AI224533 AU153442 AU151001
AU152621 AU151829 AU153069 AW269958 AU154195 AI862754 AI589780 AW273839 AI338155 AI126632 BE046048 AA976930 AI289304
AI625961 AI222288 AI280054 AA973329 AI524262 AI242371 AA296517 AI567865 AI590681 AJ346616 AW247913 AI422051 AI475352 AI689531
AW469308 AW198034 AA936939 AU151059 AU148134 AA486419 AU151953 AI830968 BI493265 BI493264 AU149861 BE268763 AV763495
AW962827 BM480300 AA226869 AL529368 BM451957 AU132714 BI871319 AA380739 BI911351 BF795906 BE548853 AW579751
430183 17316.1 AK055746 AA039909 BE183282 W60721 AA464867 AA398986 T67280 BF995651 AI675065 BG001051 BF764727 BF766707 BF764717 BF764852
BF173139 BE010038
430504 5477.6 BE219720 BF475241 AI571723 BE219848 BI789268 AI224899 AA724864 AW771467 AA480255 AW845616 AI440295 H52800 BE218790 AI681575
AW300064 AW262133 H21568 AI363015 AI884914 H86948
428612 1383189.1 AA770001 AA431112AA432126 409670 8882.8 AI625045 AW504152 AI469086 AA905873 AW504662 AW136114 AI927270 BE041754 AI648386 AA662655 AA400052 AI143501 AI744934
AI400147 AI381657 AA676551 AA974367 AW117437 AI570383 AI242456 AI274581 AA678138 R49939 AI393926 AA345854 AW605850 AI869780
AW391171 R77044
418574 12009 2 AW955043 AI990326 AA776406 AI016250 AW451882 AA843678 BF916900 AW945895 AI979339 N23129 W70051 AA322672 N23137 409019 32320.4 BM480413 N28908 H39792 BE240826 BE882093 BE240827 AW868637 BF739795 AA700834 AA769597 AA489668 AW968806 AW085196
AI093280 AI218457 AA063138 AI632958 AW515005 AI570530 Z41724 AA748789 AI696584 AA062544 AA773643 AA490285
430935 15297.3 BC017923 AA789302 AW466994 BF513878 AI819642 AI184913 AW469044 AI220572 AW072916 AI280239 AI473611 AW841126 D60937
AA489195 N59350 AA693435 BG531204 AA484243 AW514092
424677 2518.37 U09414 NM.003438 AA503545 AI022449 AA043458 AA766074 AA765442 AA805052 AI028211 AW609708
TABLE 51 C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
406547 7711513 Minus 172780-174358
402145 8018280 Plus 113086-114800
402199 8576116 Minus 84187-84744
401435 8217934 Minus 54508-55233
402408 9796239 Minuε 110326-110491
406367 9256126 Minuε 58313-58489
402680 8113438 Plus 137634-137768,139702-139893,140475-14059
402299 6693370 Plus 23367-25175
401091 9958240 Plus 94760-94898 401464 6682291 Minus 170688-170834
403969 8569909 Plus 31237-31375,32405-32506
401837 7630990 Minus 120993-121095,121660-121729
404068 3168621 Minus 18123-18766
403137 9211494 Minus 92349 92572,9295893084,93579 93712,9394
402679 8113438 Plus 132079 132216
403780 8076989 Plus 93160-93409
404071 7210053 Minus 167354-167859,168810-168920,169000 16910
403242 7637817 Minus 11297-12511
402260 3399665 Minus 113765-113910 115653-115765,116808 11694
400587 9887626 Plus 25435-25588,25668 25747
405770 2735037 Plus 61057-62075
403532 8076842 Minus 81750 81901
406137 9166422 Minus 30487-31058
402677 8113438 Plus 22135-22309,23063-23238
402678 8113438 Plus 37395-37514,37866-37981
TABLE 52A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεioπ number, Genbank acceεεioπ number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of testicular cancer (non seminomatouε and Semmomatous) compared to normal adult testicular tissues
Pkey ExAccn UnigenelD Unigene Title R1
414438 AI879277 Hs 76136 thioredoxm 51 77
424247 X14008 Hs 234734 lysozyme (renal amyloidoεis) 4993
416680 AW245540 Hs 79516 brain abundant, membrane attached signal 49 20
412948 BE243313 Hs 334851 LIM and SH3 protein 1 4446
438091 AW373062 nuclear receptor subfamily 1 , group I, m 4070
406658 AI920965 Hε 77961 major histxompatibility complex, class 39 64
418174 L20688 Hs 83656 Rho GDP dissxiation inhibitor (GDI) bet 3870
409038 T97490 Hs 50002 small inducible cytokine subfamily A (Cy 3825
413063 AL035737 Hs 75184 chitmase 3-lιke 1 (cartilage glycoprote 37 50
430542 AI557486 Hs 119122 πbosomal protein L13a 37 22
428928 BE409838 Hs 194657 cadhenn 1 , type 1, E-cadheπn (epitheli 3598
432730 AI066520 Hs 131358 ESTs 3525
444562 AA186715 Hs 336429 RIKEN CDNA 9130422N19 gene 31 69
446525 AW967069 Hs 211556 hypothetical protein MGC5487 31 33
417088 M54915 Hs 81170 pιm-1 oncogene 31 20
418870 AF147204 Hε 89414 chemokine (C-X-C motif), rxeptor 4 (fuε 2993
433800 AI034361 Hε 135150 lung type-l cell membrane aεεxiated gly 2935
426295 AW367283 zinc finger protein 6 (CMPX1) 2932
406856 AW515336 Hε 29797 πbosomal protein L10 28 93
417139 M69043 Hε 81328 nuclear fxtor of kappa light polypepfid 2799
440207 AI371978 Hs 128326 ESTs 2775
422578 AF239666 Hs 1545 caudal type homx box transcnption fxt 2695
432359 AA076049 Hs 274415 Homo sapienε cDNA FLJ10229 fis, clone HE 2690
420367 AA259090 Hs 257028 ESTs 26 50
429978 AA249027 πbosomal protein S6 2643
440440 Z28925 Hs 7188 sema domain, immunoglobulin domain (Ig), 2636
423673 BE003054 Hs 1695 matnx metalloprotemase 12 (mxrophage 26 23
412636 NM 004415 deεmoplakin (DPI, DPII) 26 15
435538 AB011540 Hs 4930 low density iipoprotem rxeptor-related 2525
446899 NM 005397 Hs 16426 podxalyxin-like 25 25
442562 BE379584 dolichyl jiphosptiooligosxchaπde-protei 25 15
406656 M16714 Hs 89643 major histocompalibility complex, class 25 13
446619 AU076643 Hs 313 sxreted phosphoprote 1 (osteopoπt , 2478
423961 D13666 Hs 136348 penostιn(OSF-2os) 2448
425543 R23313 Hs 334895 πbosomal protein L10a 2438
420676 AI434780 Hs 4248 vav 2 oncogene 24 18
406820 AI223958 Hs 108124 ribosomal protein S4, X-linked 2396
440869 NM.014297 Hs 7486 protein expressed in thyroid 2380
447526 AL048753 Hs 303649 small inducible cytokine A2 (moπxyte ch 2356
414587 NM 004862 Hs 76507 LPS-mduced TNF-alpha fxtor 2322
446627 AI973016 Hs 15725 hypothetical protein SBBI48 2293
449571 AW016812 Hs 200266 ESTε 2283
413787 AI352558 tyroεine 3-monooxygenase/tryptophan 5-mo 2281
410315 AI638871 Hs 17625 Homo sapiens cDNA FLJ22524 fis, clone H 2268
414092 Z14244 Hs 75752 cytxhrome c oxidaεe εubumt Vllb 2245
422714 AB018335 Hs 119387 KIAA0792 gene product 2245
439180 AI393742 Hs 199067 v-erb-b2 avian erythroblastic leukemia v 2230
444784 D12485 Hs 11951 ectonuclxtide pyrophosphatase/phosphodi 21 69
406648 AA563730 Hs 277477 major histxompatibility complex, class 21 58
448588 AI970276 Hs 156905 KIAA1676 21 23
433423 BE407127 Hs 8997 heat shxk 70kD protein 1 A 21 19
429490 AI971131 Hs 23889 ESTs Weakly similar to ALU7.HUMAN ALU S 2070
432606 NM 002104 Hs 3066 granzyme K (senne protease, granzyme 3, 2060
407862 BE548267 Hs 337986 Homo sapiens cDNA FLJ10934 fis, clone OV 2057 420754 W79431 Hs 346911 ribosomal protein L22 2040
425769 U72513 Hs 159486 Human RPL13-2 pseudogene mRNA complete 20 15
424800 AL035588 Hs 153203 MyoD family inhibitor 20 10
412915 AW087727 Hs 74823 NM.004541 Homo sapiens NADH dehydrogenas 2001
452322 BE566343 Hs 28988 glutaredoxm (thioltransferase) 1989
410143 AA188169 KIAA1191 protein 1941
420759 T11832 Hs 127797 Homo sapiens cDNA FLJ 11381 fis, clone HE 1908
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 1903
425535 AB007937 Hs 158287 KIAA0468 gene product 1878
411573 AB029000 Hs 70823 KIAA1077 protein 1863
452874 AK001061 Hs 30925 hypothetical protein FU10199 1853
408669 AI493591 Hs 78146 platelet endothelial cell adhesion molec 1852
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 1850
426083 AW962712 Hs 126712 ESTε, Weakly similarto AF191020 1 E2IG5 1850
429183 AB014604 Hs 197955 KIAA0704 protein 1848
450000 AI952797 Hs 10888 hypothetical protem FLJ21709 1844
450377 AB033091 KIAA1265 protein 1840
430255 AK000703 Hs 323822 Homo sapienε mRNA for KIAA1551 protein, 18 15
440528 BE313555 Hs 7252 KIAA1224 protem 1805
444381 BE387335 Hε 283713 ESTε, Weakly similar to S64054 hypotheti 1798
420028 AB014680 Hs 8786 carbohydrate (N acetylglucosamine 6 O) s 1780
414682 AL021154 Hs 76884 inhibitor of DNA binding 3, dominant neg 1775
428782 X12830 Hs 193400 interieukin 6 receptor 1748
415221 W07418 Hs 78225 annexm A1 1747
429614 AI371172 Hs 211539 hypothetical protein MGC4248 1740
418707 U97502 Hs 87497 butyrophilin, subfamily 3, member A2 1730
412025 AI827451 Hs 24143 Wiskott-Aldπch syndrome protein interx 17 14
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 1713
424326 NM_014479 Hs 145296 ADAM like disintegnn proteaεe, dxyεm 17 10
446921 AB012113 Hs 16530 εmall inducible cytokine εubfamily A (Cy 1703
425996 W67330 hypothetical protein AL110115 1698
402474 NM.004079 Homo εapieπs cathepsin S (CTSS 1698
450937 R49131 Hs 26267 ATP-dependant interferon response protei 1698
427521 AW973352 ESTs 1693
421181 NM 005574 Hs 184585 LIM domain only 2 (rhombotin like 1) 1693
443523 AK001575 Hs 9536 hypothetical protein FU10713 1653
449338 H73444 Hs394 adrenomedullin 1636
429469 M64590 Hs 27 glycine dehydrogenase (decarboxylatiπg, 1623
425945 AW410669 Hs 164280 solute camerfamily 25 (mitxhondπal 1621
430332 R51790 Hs 239483 Human clone 23933 mRNA sequence 16 15
427691 AW194426 Hs 20726 ESTs 16 13
406786 AW161678 Hs 111334 ferntiπ, light polypeptide 1611
431639 AK000680 Hs 266175 phosphoprotein assxiated with GEMs 16 10
451106 BE382701 Hs 25960 N MYC oncogene 1609
408380 AF123050 Hs 44532 diubiquitm 1600
445863 R12234 Hs 13396 Homo sapiens clone 25028 mRNA sequence 1593
456236 AF045229 Hs 82280 regulator of G-protein signalling 10 1570
406791 AI220684 Hs 347939 hemoglobin, alpha 2 1569
414020 NM 002984 Hs 75703 small inducible cytokine A4 (homologous 1564
440273 AI805392 Hs 325335 Homo sapienε cDNA FU23523 fis, clone L 1555
417640 D30857 Hs 82353 protein C rxeptor, endothelial (EPCR) 1555
446108 AL036596 Hs 42322 A kinase (PRKA) anchor protein 2 1553
410185 BE294068 Hs 737 immediate early protein 1549
422105 AI929700 Hs 111680 endosulfine alpha 1523
415899 X78992 Hs 78909 butyrate reεponse fxtor 2 (EGF-reεponεe 1523
428227 AA321649 Hs 2248 εmall inducible cytokine subfamily B (Cy 1505
427820 BE222494 Hs 180919 inhibitor of DNA binding 2, dominant neg 1502
426552 BE297660 Hs 170328 moesm 1496
422241 Y00062 Hs 170121 protein tyrosine phoεphataεe, rxeptor t 1488
436860 H12751 Hs 5327 PR01914 protein 1485
418509 AB028624 Hs 85539 ATP synthaεe, H transporting, mitxhondr 1484
444060 AA340277 Homo sapiens cDNA FLJ20167 fis, clone CO 1478
412623 R28898 Hs 74170 metallothioπein 1E (functional) 1470
408989 AW361666 Hs 49500 KIAA0746 protein 1453
425234 AW152225 Hs 165909 ESTs, Weakly similar to 138022 hypotheti 1448
417144 AA382104 Hs 81337 lectm, gaiactoside-binding, soluble, 9 1431
410325 AB023154 Hs 62264 KIAA0937 protein 1423
415938 BE383507 Hs 78921 A k ase (PRKA) anchor protein 1 1420
433412 AV653729 Hs 8185 CGI-44 protein, sulfide dehydrogenase Ii 1419
418151 AA864238 Hs 83583 xtin related protein 2/3 complex, subun 1418
426996 AW968934 Hs 173108 Homo sapiens cDNA FU21897 fis, clone H 14 13
447211 AL161961 Hs 17767 KIAA1554 protein 1408
417426 NM 002291 I Hs 82124 laminin, beta 1 1408
414420 AA043424 Hs 76095 immediate early responεe 3 1404
444051 N48373 Hs 10247 xtivated leucxyte cell adheεion molxu 1402
454413 A1653672 Hs 40092 PNAS-123 1393
452651 AI218918 Hs 30209 KIAA0854 protein 1386
450581 AF081513 Hs 25195 TGF-beta 4 1385
420962 NM 005904 Hs 100602 MAD (mothers against decapentaplegic, Dr 1378
407112 AA070801 Hs 51615 ESTs, Weakly similar to ALU7.HUMAN ALU S 1363
410598 AI817130 Hs 9195 Homo sapiens cDNA FLJ13698 fis, clone PL 13 59
428664 AK001666 Hs 189095 similar to SALL1 (sal (Drosophila) like 1357
448412 AI219083 Hs 42532 ESTs, Moderately similar to ALU8.HUMAN A 13 53 430268 AK000737 Hs 237480 hypothetical protein FLJ20730 1343
445055 BE512856 Hs 109051 SH3 domain binding glutamic acid rich pr 1341
447534 AW953935 Hs 288655 ESTε 1333
408822 AW500715 Hs 57079 Homo εapiens cDNA FLJ 13267 fis, clone OV 13 31
428065 AI634046 Hs 157313 ESTs 13 30
425289 AW139342 Hs 155530 interferon, gamma inducible protein 16 13 28
436398 H87136 Hs 5174 nbosomal protein S17 13 18
453856 AA804789 Hs 19447 PDZ-LIM protein mystique 1293
452436 BE077546 Hs 31447 ESTs, Moderately similar to A46010 X lin 12 90
445817 NM 003642 Hs 13340 histone acetyltransferase 1 1290
408437 AW957744 Hs 278469 Ixπmal proline rich protein 12 90
435522 N64214 Hs 9774 synovial εarcomatranεlocation gene on c 1289
415857 AA866115 Hs 127797 Homo εapienε cDNA FLJ11381 fis, clone HE 1283
406743 AA911568 Hs 279860 tumor protein, translationally-controlle 1279
407951 W77762 Hs 79015 antigen identified by onxloπal antibod 1278
435080 AI831760 Hs 155111 hypothetical protein FLJ 14428 12 75
418299 AA279530 Hs 83968 integπn, beta 2 (antigen CD18 (p95), ly 1273
430630 AW269920 Hs 2621 cystatin A (stefin A) 1268
409208 Y00093 integnn, alpha X (antigen CD11C (p150), 1265
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 12 50
438915 AA280174 Hs 285681 Williams-Beuren syndrome chromosome regi 1248
437374 AL359571 Hs 44054 niπein (GSK3B interacting protein) 1243
433793 AW975959 Hε 107513 ESTs, Moderately similar to KIAA1058 pro 1243
409963 AA133590 Hs 250857 calcium/calmodulin dependent protein kin 1241
412247 AF022375 Hs 73793 vascular endothelial growth fxtor 1241
413497 BE177661 gb RC1-HT0598 020300-011-h02 HT0598 Homo 1240
436876 AI124756 Hs 5337 lεxitrate dehydrogenase 2 (NADP), mitx 1238
432409 AA806538 Hs 130732 KIAA1575 protein 1233
453020 AL162039 Hs 31422 Homo sapiens mRNA, cDNA DKFZp434M229 (fr 1233
419384 AA490866 Hs 39429 ESTs 1233
410275 U85658 Hs 61796 transcnption fxtor AP-2 gamma (xtivat 1232
432805 X94630 Hs 3107 CD97 antigen 1232
416975 NM 004131 Hs 1051 granzyme B (granzyme 2, cytotoxic T-lymp 1225
450719 AI096837 Hs 21349 ESTs, Weakly similar to RB8B.HUMAN RAS R 12 13
423753 Y11312 Hs 132463 phosphoinositide 3-kmase, class 2, beta 12 12
418460 M26315 Hs 85258 CD8 antigen, alpha polypeptide (p32) 1203
402145 Target Exon 1201
407179 AA206465 thymosin, beta 4, X chromosome 1200
433208 AW002834 Hs 24095 ESTs 11 95
447735 AA775268 Hs 6127 Homo sapiens cDNA FLJ23020 fis, clone L 11 90
408912 AB011084 Hs 48924 KIAA0512 gene product, ALEX2 11 83
422068 AI807519 Hs 104520 Homo sapienε cDNA FLJ13694 fiε, clone PL 11 75
431427 AK000401 Hs 252748 Homo εapieπs cDNA FLJ20394 fis, clone KA 11 75
427761 AA412205 Hs 140996 ESTs 11 68
449246 AW411209 Hs 23363 hypothetical protein FLJ 10983 11 58
436075 BE0901 6 Hs 179902 transporter-like protein 11 50
440774 AI420611 Hs 153934 ESTs 11 35
430594 AK000790 Hs 246885 hypothetical protein FU20783 11 25
419223 X60111 Hs 1244 CD9 antigen (p24) 11 08
424528 AW073971 Hs 238954 ESTs, Weakly similar to KIAA1204 protein 11 08
444656 AI277924 Hs 145199 ESTs 1098
420943 AI718702 Hs 279930 major histxompatibility complex, clasε 1096
450294 H42587 Hs 238730 hypothetical protein MGC10823 1092
413686 AI469213 Hs 71404 ESTs 1083
406701 AA780613 Hs 62954 fe tin, heavy polypepbde 1 1078
424687 J05070 Hs 151738 matnx metalloproteinase 9 (gelatinase B 1075
407252 AA659037 Hs 163780 ESTε 1075
445929 AI089660 Hs 323401 dpy-30-lιke protein 1070
451864 N20370 Hs 69547 ESTs 1069
429307 AU076592 Hs 198951 jun B proto-oncogene 1064
434280 BE005398 gb CM1-BN0116-150400489 h02 BN0116 Homo 1063
447519 U46258 Hs 339665 ESTs 1063
417365 D50683 Hs 82028 transforming growth fxtor, beta rxepto 1059
418945 BE246762 Hs 89499 arxhidonate 5-lιpoxygenaεe 1055
406776 T16206 Hs 237164 ESTε, Highly similarto LDHH HUMAN L-LAC 10 54
437103 AW139408 Hs 152940 ESTs 1050
449961 AW265634 Hs 133100 ESTε 10 50
441244 BE612935 Hs 184052 PP1201 protein 1049
450139 AK001838 εerum/glucxorticoid regulated kinaεe 1048
427202 BE272922 Hs 173936 interleukin 10 rxeptor, beta 1048
449944 AF290512 Hs 58215 Homo sapiens, Similar to rhotekm, clone 1047
446682 AW205632 Hs 211198 ESTs 1043
413886 AW958264 Hs 103832 similar to yeast Upf3, vaπant B 1043
430068 AA464964 gb zxδOflO ε1 Soareε ovary tumor NbHOT H 1040
424950 AA602917 Hs 156974 ESTs 1040
434442 AA737415 ESTs 1033
438089 W05391 nuclear receptor subfamily 1, group I, m 1033
432559 AW452948 Hs 257631 ESTs 1030
414191 AW250089 Hs 75807 PDZ and LIM domain 1 (elfin) 1030
434649 AA738254 Hs 165390 ESTs, Highly similar to A40350 transcnp 1028
424321 W74048 Hs 1765 lymphxyte εpecific protein tyroεine kin 10 27
452568 AA805634 Hs 300870 Homo εapienε mRNA, cDNA DKFZp547M072 (fr 1027
419490 NM 006144 Hs 90708 granzyme A (granzyme 1 , cytotoxic T-lymp 10 23 445245 AB032973 Hs 12461 LCHN protein 10 18
446488 AB037782 Hε 15119 KIAA1361 protein 10 15
410611 AW954134 Hs 20924 KIAA1628 protein 10 15
425875 AU077333 Hs 160483 erythrocyte membrane protein band 7 2 (s 10 14
416926 H03109 Hs 263395 HT018 protein 1007
420225 AW243046 Hs 282076 Homo εapienε mRNA for KIAA1650 protein, 1005
445577 N40696 Hs 137064 cytoplasmic polyadenylation element bind 1004
411975 AI916058 Hs 144583 ESTs 1003
447644 AW861622 Hs 108646 Homo sapienε cDNA FLJ14934 fis, clone PL 1000
408784 AW971350 Hs 63386 ESTs 995
444795 AI193356 Hs 160316 ESTs 993
407110 AA018042 Hs 252085 Prader-Willt/Angelman syπdrome-5 990
400440 X83957 Hs 83870 nebulm 990
414829 AA321568 Hs 77436 pleckstπn 988
427711 M31659 Hs 180408 solute earner family 25 (mitochondnal 988
426827 AW067805 Hs 172665 methylenetetrahydrofolate dehydrogenase 985
456362 AW973003 Hs 179909 hypothetical protein FLJ22995 983
446795 AI797713 Hs 156471 ESTs 978
424201 L33075 Hs 1742 IQ motif containing GTPase activating pr 967
422627 BE336857 Hs 118787 transforming growth fxtor, beta-induced 965
419904 AA974411 Hs 18672 ESTs 963
451129 BE072881 gb RC2-BT0548 200300 012-e09 BT0548 Homo 963
414405 AI362533 KIAA0306 protein 9 58
418840 AI821614 Hs 185831 ESTs 953
453716 AA037675 Hs 152675 ESTs 9 50
415323 BE269352 Hs 949 neutrophil cytosolic fxtor 2 (65kD, chr 950
415189 L34657 Hs 78146 platelet/endothelial cell adhesion molx 945
408360 AI806090 Hs 44344 hypothetical protein FU20534 945
423024 AA593731 Hs 325823 ESTs, Moderately similar to ALU5.HUMAN A 943
434423 NM 006769 Hs 3844 LIM domain only 4 943
437469 AW753112 Hs 15514 hypothetical protein MGC3260 943
416078 AL034349 Hs 79005 protein tyrosine phoεphatase, rxeptor t 942
410397 AF217517 Hs 63042 DKFZp564J157 protein 937
422603 BE242587 Hs 118651 hematopoietically expressed homeobox 937
434524 AA635931 Hs 249716 ESTs 936
422960 AW890487 cadhenn 13, H-cadheπn (heart) 935
414774 X02419 Hε 77274 plaεmiπogen activator, urokmase 932
411960 R77776 Hs 18103 ESTs 930
428818 AI131291 Hs 102308 potassium mwardly-rxtifyiπg channel, s 928
408161 AW952912 Hs 300383 hypothetical protein MGC3032 9 28
441455 AJ271671 Hs 7854 zinc/iron regulated transporter-like 927
433271 BE621697 Hs 14317 nucleolar protein family A, member 3 (H/ 927
436823 AW749865 Hs 117077 ESTs, Weakly similar to 138022 hypotheti 925
427968 AI857607 Hs 181301 cathepsin S 923
420059 AF161486 Hs 94769 RAB23, member RAS oncogene family 9 23
410730 AW368860 DnaJ (Hsp40) homolog, subfamily B, membe 923
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (placenta 918
417315 AI080042 Hε 180450 nbosomal protein S24 918
421098 AI697901 Hs 192425 ESTs 918
422689 AW856665 gb RC3-CT0297-290100-013-d03 CT0297 Homo 918
433156 R59206 Hs 17519 Homo sapiens cDNA FU22539 fis, clone H 917
425246 AI085561 Hs 155321 serum responεe factor (c-fos serum respo 917
440268 BE270030 Hs 336959 Homo sapiens, clone IMAGE 3677185, mRNA 9 15
414821 M63835 Hs 77424 Fc fragment of IgG, high affinity la, re 914
407254 AW129401 Hs 181165 eukaryotic translation elongation fxtor 9 13
426689 BE245550 Hs 171825 basic helix-loop-helix domain containing 912
420099 D80011 Hs 95140 KIAA0189 gene product 910
424768 AA353895 Hs 152983 HUS1 (S pombe) chxkpo t homolog 908
441436 AW137772 Hs 185980 ESTs 908
448019 AW947164 Hs 195641 ESTs, Moderately similar to I38022 hypot 908
437886 BE264111 Hs 31314 retinoblastoma-binding protein 7 908
430556 AW967807 Hs 13797 ESTs 907
450147 AW373713 Hs 146324 CGI-145 protein 906
442806 AW294522 Hs 149991 ESTs 905
431187 AW971146 Hs 293187 ESTs 905
449971 AA807346 Hs 288581 Homo sapiens cDNA FLJ14296 fis, clone PL 903
417018 M16038 Hs 80887 v-yes-1 Yamaguchi sarcoma viral related 903
422451 AA310753 Hs 42491 ESTs, Weakly similar to S65657 alpha-1 C- 902
419839 U24577 Hs 93304 phospholφase A2, group VII (platelet-x 900
409493 AA386192 Hs 193482 Homo sapiens cD A FU 11903 fis, clone HE 899
432314 AA533447 Hs 312989 ESTs 8 98
414591 AI888490 Hs 55902 ESTs, Weakly similar to ALU8.HUMAN ALU S 895
415825 Y18024 Hs 78877 inositoi 1,4,5-tnsphosphate 3-kιnase B 894
429500 X78565 Hs 289114 hexabrachion (tenascm C, cytotactin) 893
420337 AW295840 Hs 14555 Homo sapiens cDNA FU21513 fis, clone C 890
452679 Z42387 Hs 83883 transmembrane, prostate androgen induced 890
437108 AA434054 Hs 80624 hypothetical protein MGC2560 889
417228 AL134324 Hs 7312 ESTε 888
425593 AA278921 Hs 1908 proteoglycan 1, εxretory granule 8 88
422616 BE300330 Hs 118725 εelenophosphate synthetase 2 888
438980 AW502384 gb UI HF-BROp aka-f-12-0-UI NIH.MGC.5 885
429109 AL008637 Hs 196352 neutrophil cytosolic factor 4 (40kD) 8 85
444933 NM 01624E i Hs 12150 retinal short-chain dehydrogenase/reduct 885 430592 AJ224864 Hs 9688 leukocyte membrane antιgen(IRCI) 8 83
445612 N94126 Hs 12969 hypothetical protein 880
427254 AL121523 Hs 97774 ESTs 8 80
428970 BE276891 Hs 194691 retinoic acid induced 3 880
425190 AW028302 Hs 155079 protein phosphatase 2, regulatory subuπi 879
430162 AW450843 Hs 346348 ESTs 875
421684 BE281591 Hs 106768 hypothetical protein FLJ 10511 873
446659 AI335361 Hs 226376 ESTs 873
447198 D61523 Hs 283435 ESTs 873
437457 AA757900 Hs 270823 ESTε, Weakly similar to S65657 alpha 1C- 870
401091 dxay accelerating factor for complement 868
442832 AW206560 Hs 253569 ESTs 868
442495 AI184717 ESTs 8 63
428467 AK002121 Hs 184465 hypothetical protein FLJ 11259 863
449924 W30681 Hs 146233 Homo sapiens cDNA FLJ22130 fis, clone H 861
447674 BE270640 Hs 19192 cyclm-dependent kinase 2 859
425580 L11144 Hs 1907 galanm 855
449656 AA002008 Hs 188633 ESTs 8 55
412093 BE242691 Hs 14947 ESTs 854
407833 AW955632 Hs 66666 ESTs, Weakly similar to S19560 proline-r 8 54
411979 X85134 Hs 72984 ret oblastoma binding protein 5 853
437134 AA349944 Hs 42915 ARP2 (actm related protein 2 yeast) ho 851
430333 S70114 Hs 239489 TIA1 cytotoxic granule-ass∞ialed RNA-bi 845
408996 AI979168 Hs 344096 glycoprotein (transmembrane) nmb 845
425284 AF155568 NS1-assooιated protein 1 845
441623 AA315805 desmoglein 2 843
442622 NM 000435 Hs 8546 Notch (Drosophila) homolog 3 842
441021 AW578716 Hs 7644 H1 histone family, member 2 840
446630 AW384793 Hs 15740 Homo sapiens mRNA, cDNA DKFZp434E033 (fr 840
417621 AV654694 Hs 82316 interferon induced, hepatitis C-associat 835
433655 AL036559 Hs 3463 nbosomal protein S23 833
449335 AW150717 Hs 345728 STAT induced STAT inhibitor 3 832
446975 BE246446 Hs 16695 ubiquitin-activatmg enzyme E1-lιke 831
436797 AA731491 Hs 334477 hypothetical protein MGC14879 830
414662 AL036058 Hs 76807 major histocompatibility complex, class 830
414601 AV660804 Hs 301417 AHNAK nucleoprotem (desmoyokm) 829
406699 L06505 Hs 182979 πbosomal protein L12 828
443884 N20617 Hε 194397 lept rxeptor 828
442821 BE391929 Hε 8752 transmembrane protein 4 826
418522 AA605038 Hs 7149 Homo sapienε cDNA FLJ21950 fis, clone H 824
435968 AW161481 Hs 111577 integral membrane protein 3 823
440327 R12581 Hε 191146 ESTs 823
409327 L41162 Hε 53563 collagen, type IX, alpha 3 822
435684 NM 001290 Hs 4980 LIM domain binding 2 816
430299 W28673 Hs 106747 senne carboxypeptidase 1 precursor prot 815
427523 BE242779 Hs 179526 upregulated by 1,25-dιhydroxyvιtamιn D 3 814
407151 H25836 Hs 301527 ESTs, Moderately similar to unknown [H s 813
448094 H24387 Hs 32061 ESTs, Weakly similar to I38022 hypotheti 810
421395 D90084 Hs 1023 pyruvate dehydrogenase (lipoamide) alpha 809
431574 AW572659 Hs 261373 hypothetical protein dJ4340143
412645 AW444433 Hs 136061 Homo sapienε, Similar to hypothetical pr 807
423523 AW299828 Hs 193580 ESTs 803
426759 AI590401 Hs 21213 ESTs 803
426780 BE242284 Hs 172199 adenylate cyclase 7 803
426215 AW963419 Hs 155223 stannixalcin 2 803
435748 AA699756 Hs 117335 ESTε 800
443351 AW016783 Hs 30799 Homo sapiens cDNA FLJ13471 fis, clone PL 800
447500 AI381900 Hs 159212 ESTε 800
407949 W21874 Hs 247057 ESTε, Weakly similar to 2109260A B cell 800
428728 NM 016625 Hs 191381 hypothetical protein 800
434511 R28982 Hs 18106 ESTs 799
411852 AA528140 Hs 107515 ESTs, Weakly similar to T00329 hypotheti 798
424875 AH 87945 Hs 199310 ESTs 795
419378 R24922 Hs 90078 nucleotide-sugar transporter similar to 795
449523 NM 000578 I Hs 54443 chemokine (C-C motif) rxeptor 5 793
425277 NM 001241 Hs 155478 cyclin T2 791
451831 NM 00167 1 Hs 460 xuvating transcnption fxtor 3 790
443303 U67319 Hs 9216 caspase 7, apoptosis-related cysteine pr 790
407013 U35637 Hs 83870 gb Human nebulin mRNA, partial eds 790
429999 AI761902 Hs 99597 ESTs 790
445493 AI915771 metallotfnonein 1E (functional) 789
413420 AW410235 Hs 75348 proteasome (prosome, mxropain) xtivato 788
422392 NM 005908 Hs 115945 mannoεidaεe, beta A, lyεosomal 788
453485 BE620712 Hs 33026 hypothetical protein PP2447 787
434159 AW135214 Hs 191828 ESTε 785
432666 AW204069 ESTs, Weakly similar to unnamed protein 783
430915 AA488953 gb aa55e05 r1 NCI.CGAP.GCB1 Homo sapiens 783
425913 AA365799 SEC22, vesicle trafficking protein (S c 780
448776 BE302464 Hs 30057 MRS2 (S cerevisiae) like, magnesium hom 780
438763 AI583207 Hs 99029 CCAAT/enhancer binding protein (C/EBP), 779
435905 AW997484 Hs 5003 KIAA0456 protein 778
406663 U24683 immunoglobulin heavy constant mu 778
427395 AW298741 Hs 97861 ESTs, Moderately similar to 138022 hypot 778 446272 BE268912 Hs 14601 hematopoietic cell spxific Lyn substrat 775
438962 BE046594 gb hn41c11 x1 NCI.CGAP.RDF2 Homo sapiens 775
434963 AW974957 Hs 288719 Homo sapienε cDNA FLJ12142fis, clone MA 773
422900 AA641201 Hs 222051 ESTs 773
432598 AI341227 Hs 157106 ESTs 772
449322 AI638616 Hs 196566 ESTs 771
416987 D86957 Hs 80712 KIAA0202 protein 7 67
410800 BE280421 Hs 94499 ESTε 7 67
416801 X98834 Hs 79971 εal (Drosophila) like 2 7 67
437442 T85104 Hs 222779 ESTs, Moderately similar to similar to N 765
407137 T97307 gb ye53h05 s1 Soares fetal liver spleen 7 65
401466 vesicle assxiated membrane protein 4 765
406870 AA075144 gb zm86f06 s1 Stratagene ovanan cancer 7 64
408558 AW015759 Hs 235709 Homo εapiens mRNA, cDNA DKFZp667B0711 (f 763
457250 AA811987 Hs 125779 ESTs 763
412949 AI471639 Hs 71913 ESTs 763
406819 AA908472 gb og82a10 s1 NCI.CGAP.Ov8 Homo εapiens 762
441612 AI802629 Hs 113660 Homo sapiens cDNA FLJ11631 fis, clone HE 7 62
414799 AI752416 Hs 77326 insulin like growth fxtor binding prote 761
435937 AA830893 Hs 119769 ESTs 7 60
447197 R36075 gb yh88b01 s1 Soares placenta Nb2HP Homo 760
407719 AW963866 Hs 44021 Homo sapienε mRNA for FLJ 00065 protein, 760
417336 R70429 Hs 81988 disabled (Drosophila) homolog 2 (mitogen 756
418134 AA397769 Hs 86617 ESTε 7 55
451812 X81889 Hs 152151 plakophilin 4 755
412347 AW970026 Hε 73818 ubiquinol-cytochrome c reductase hinge p 754
429083 Y09397 Hε 227817 BCL2-related protein A1 754
414004 AA737033 Hε 7155 ESTs, Moderately similar to 2115357A TYK 752
423905 AW579960 Hε 135150 lung type I cell membrane-aεεxiated gly 752
407784 AW139585 Hs 12708 ESTs 7 52
425762 BE244076 Hs 159578 AT-hook transcnption factor AKNA 750
418452 BE379749 Hs 85201 C-type (calcium dependent, carbohydrate- 7 50
438459 T49300 Hs 35304 Homo εapienε cDNA FLJ 13655 fiε, clone PL 748
446013 AI360167 Hs 152774 ESTε 748
429281 AA830856 Hs 29808 Homo εapienε cDNA FLJ21122 fiε, clone C 748
415526 N76536 Hs 265591 ESTε, Weakly similar to ALU1.HUMAN ALU S 745
417450 AA314435 Hs 17519 Homo sapienε cDNA FLJ22539 fis, clone H 745
431773 BE409442 Hs 268557 plxkstπn homology-like domain, family 744
447082 T85314 Hs 54629 thioredoxin like 743
441962 AW972542 Hs 289008 Homo sapienε cDNA FLJ21814 fis, clone H 743
429058 AF138863 Hs 35254 hypothetical protem FLB6421 743
439971 W32474 Hs 301746 RAP2A, member of RAS oncogene family 743
442233 AW967149 Hs 28439 ESTs, Weakly similar to I38022 hypotheti 743
436394 AA531187 Hs 126705 ESTs 739
452248 AA093668 Hs 28578 muscleblind (Drosophιla)-lιke 739
446258 AI283476 Hs 263478 ESTs 738
410570 AI133096 Hs 64593 ATP synthase, H transporting, mitxhondr 737
447484 AA464839 Hs 292566 hypothetical protein FLJ 14697 736
435541 AA687361 Hs 221318 ESTs 735
453932 AW006303 Hs 329296 ESTs, Weakly εimilar to (defline not ava 735
408067 BE244580 Hs 342307 hypothetical protein FU 10330 735
427307 AF117947 Hs 174795 PDZ domain-containing guanine nucleotide 735
418336 BE179882 glutathione peroxidase 3 (plasma) 735
448877 AI583696 Hs 253313 ESTs 735
443195 BE148235 Hs 193063 Homo sapiens cDNA FU14201 fis, clone NT 735
444838 AV651680 Hs 208558 ESTs 733
422693 BE300073 Hs 279860 tumor protein, translationally-controlle 731
424677 U09414 zinc finger protein 137 (clone pHZ-30) 730
441878 AI801869 Hε 127982 ESTε 729
406542 C19000728* gι|12585552|sp|Q9Y2Q1|Z257_HU 728
408418 AW963897 Hε 44743 KIAA1435 protein 7 28
425367 BE271188 Hs 155975 protein tyrosine phosphatase, rxeptor t 726
442492 AA528489 Hs 234518 nbosomal protein L23 7 25
424541 AW392551 Hs 180559 ESTs, Weakly similar to A56194 thromboxa 725
452852 AK001972 Hs 30822 hypothetical protein FU11110 7 25
426501 AW043782 Hs 293616 ESTs 725
411251 R19774 Hs 22835 HHGP protein 7 25
444670 H58373 Hs 332938 hypothetical protein MGC5370 725
418117 AI922013 Hs 83496 linker for xtivation of T cells 724
441384 AA447849 Hs 288660 Homo εapieπ cDNA FU22182 fiε, clone H 724
434817 AA082118 Hs 102737 goliath protein 723
419970 AW612022 ESTs 7 23
432290 AK001099 Hs 274273 Homo εapiens cDNA FLJ10237 fis, clone HE 723
426647 AA243464 Hs 294101 pre-B- ell leukemia tranεcπptioπ fxtor 7 23
433891 AA613792 gb no97h03 ε1 NCI_CGAP_Pr2 Homo sapiens 721
454038 X06374 Hs 37040 platelet deπved growth factor alpha pol i 721
430314 AA369601 Hs 239138 pre B-cell colony enhancing fxtor 720
443247 BE614387 Hs 333893 c-Myc target JP01 7 20
441224 AU076964 Hs 7753 calumemn 7 18
447188 H65423 Hs 17631 hypothetical protein DKFZp434E2135 7 18
447887 AA114050 Hs 19949 caspase 8, apoptosis related cysteine pr 715
447341 AF106941 Hs 18142 arrestin, beta 2 715
408113 T82427 Hs 194101 Homo sapienε cDNA FLJ20869 fiε, clone A 714 418696 AW959433 Hs 326290 hypothetical protein FU12581 7 14
434699 AA643687 Hs 149425 Homo sapiens cDNA FLJ11980 fis, clone HE 7 13
421633 AF121860 Hs 106260 sorting nexm 10 710
410668 BE379794 Hs 159651 hypothetical protein 709
435812 AA700439 Hs 188490 ESTs 708
414476 AA301867 Hs 76224 EGF containing fibulin like extracellula 7 08
408331 NM 007240 Hs 44229 dual specificity phosphatase 12 708
417165 R80137 Hs 302738 Homo sapiens cDNA FLJ21425 fis, clone C 706
408605 AF025374 Hs 46465 T-cell, immune regulator 1 7 06
416401 N80139 Hs 268916 ESTs 705
415799 AA653718 Hs 225841 DKFZP434D193 protein 7 05
415995 NM 004573 phospholipase C, beta 2 7 05
414812 X72755 Hs 77367 monokine induced by gamma interferon 705
417535 AA203569 Hs 191482 ESTs 704
449567 AI990790 Hs 188614 ESTs 7 03
429355 AW973253 Hs 292689 ESTs 703
442460 NM 014135 Hs 8345 PRO0641 protein 703
453187 AI161383 Hs 34549 ESTs, Highly similar to S94541 1 clone 4 7 03
430280 AA361258 Hs 237868 interleukin 7 rxeptor 703
426124 AI268389 Hs 250697 phosphatidylmositol glycan, class F 702
442685 AB033017 Hs 8594 KIAA1191 protein 701
433735 AA608955 Hs 109653 ESTs 700
416003 X98001 Hs 78948 Rab geranylgeranyltraπsferase, beta subu 698
424415 NM 001975 Hs 146580 enolase 2, (gamma, neuronal) 696
416655 AW968613 Hs 79428 BCL2/adenovιrus E1B 19kD interacting pro 695
409956 AW103364 Hs 727 inhibin, beta A (xtivm A, activin AB a 695
407136 T64896 Hs 287420 Homo sapienε cDNA FLJ 11533 fiε, clone HE 693
425235 AA353113 Hs 112497 Homo εapienε cDNA FLJ22743 fis, clone H 693
451653 W18193 ESTs, Moderately similar to HERC2 [H sap 6 93
439444 AI277652 Hs 54578 ESTs, Weakly similar to I38022 hypotheti 693
451838 AW005866 Hs 193969 ESTs 691
436812 AW298067 gb Ul-H BWO ajp-g 09 0-UI s1 NCI CGAP Su 690
443749 R38828 Hs 143463 ESTε 690
434584 D57341 Hs 188361 Homo εapiens cDNA FLJ 12807 fis, clone NT 690
427919 AA173942 Hs 326416 Homo sapiens mRNA cDNA DKFZp564H1916 (f 690
431840 AA534908 Hs 2860 POU domain, clasε 5, transcription fxto 690
435655 AW105663 Hs 6947 HSPC069 protein 690
427640 AF058293 Hs 180015 D-dopxhrome tautomerase 685
418259 AA215404 ESTs 6 85
407244 M10014 fibrinogen, gamma polypeptide 685
418832 X04011 Hs 88974 cytochrome b 245, beta polypeptide (chro 683
441321 H17182 Hs 7771 B-cell asεxiated protem 6 80
433162 AI025842 ESTs 680
425410 AA310974 Hs 156828 Homo sapiens cDNA FLJ 10522 fis, clone NT 680
434372 AA631373 gb np86c01 s1 NCI_CGAP_Thy1 Homo sapiens 680
456629 AW891965 histone deacetylase 3 678
430283 BE391688 RAB7, member RAS oncogene family 677
418300 AI433074 Hs 86682 Homo sapienε cDNA FU21578 fiε, clone C 676
406858 AI865720 Hs 29797 πbosomal protein L10 675
429582 AI569068 Hs 22247 ESTs 675
401113 solute earner family 22 (organic cation 675
449576 AW014631 Hs 225068 ESTs 675
432588 X92715 Hs 3057 zinc finger protein 74 (Coε52) 672
417558 AF045229 Hs 82280 regulator of G-protem signalling 10 672
430451 AA836472 Hs 297939 cathepsin B 672
410503 AW975746 Hs 188662 KIAA1702 protein 670
415682 AI347128 Hs 191870 ESTs 670
410102 AW248508 Hs 279727 ESTs, homologue of PEM 3 [Ciona εavigπyi 670
414217 AI309298 Hε 279898 Homo sapiens cDNA FU23165 fis, clone L 670
457073 AA233210 Hε 179943 πbosomal protein L11 669
442232 AI357813 Hs 337460 ESTε, Weakly similar to A47582 B-cell gr 668
436137 AI056769 Hs 133512 ESTs 668
425787 AA363867 Hs 155029 ESTs 667
437802 AI475995 Hs 122910 ESTs 665
432636 AA340864 Hs 278562 claudin 7 665
407340 AA810168 Hs 284289 vitiligo-assxiated protein VIT-1 665
418036 Z37976 Hε 83337 latent transforming growth fxtor beta b 665
423494 AW504365 Hε 24143 Wiskott-Aldπch syndrome protein iπterx 663
441355 AI822034 Hs 137097 ESTs 663
430968 AW972830 gb EST384925 MAGE resequences, MAGL Homo 663
434551 BE387162 Hs 280858 ESTs, Highly similar to A35661 DNA excis 663
447232 AW499834 Hs 327 interleukin 10 rxeptor, alpha 662
422310 AA316622 Hs 98370 cytxhrome P450, εubfamily IIS, polypept 660
449217 AA278536 Hs 23262 πbonuclease, RNase A family, k6 660
449057 AB037784 Hs 22941 KIAA1363 protein 660
446979 AI654443 Hs 197683 ESTs 660
452382 N38902 Hs 211539 hypothetical protein MGC4248 660
424868 AI568170 Hs 96886 ESTs 659
409485 S80990 Hs 252136 ficolin (collagen/fibπnogen domam-cont 658
451603 BE379499 Hs 173705 Homo sapiens cDNA FLJ22050 fis, clone H 658
426158 NM 001985 ! Hs 199067 v-erb b2 avian erythroblastic leukemia v 658
452472 AW957300 Hs 294142 ESTs, Weakly similar to C55663 oligodend 6 57
450256 AA286887 Hs 24724 MFH amplified sequences with leucine nc 656 451589 AA424791 Hs 5734 memngioma expressed antigen 5 (hyaluron 656
444207 AI565004 cathepsin D (lysosomal aspartyl protease 655
418459 R85436 Hs268814 ESTs 6 55
427667 AK001279 Hs 180171 Homo sapiens cDNA FLJ10417 fis clone NT 655
406745 AW511970 Hs 279860 tumor protein (ranslationally-controlle 655
446173 BE565849 Hε 14158 copme III 6 53
436566 BE545586 Hs278712 Homo εapiens cDNA FLJ 11074 fis clone PL 653
423825 NM 004402 Hs 133089 DNA fragmentation factor, 40 kD, beta po 6 53
443441 AW291196 Hs 92195 ESTs 651
428403 AI393048 Hs 326159 leucine rich repeat (in FLU) teractin 650
431971 BE274907 Hs 77385 myosin, light polypeptide 6, alkali, smo 650
450219 AI826999 Hs224624 ESTs 6 50
408896 A1610447 Hs 48778 πiban protein 650
442618 R56222 Hs 26514 ESTs 649
422773 AB028962 Hs 301552 KIAA1039 protein 648
413663 BE247585 Hs75462 BTG family, member 2 648
418905 BE539674 xtinm, alpha 4 648
405086 NM.006662* Homo sapienε Snf2-related CBP 645
448520 AB002367 Hs 21355 doublecortin and CaM kinase like 1 645
407284 AI539227 Hs 214039 hypothetical protein FLJ23556 645
447296 AW243614 Hs18063 Homo sapiens cDNA FLJ10768 fis, clone NT 645
443963 AA878183 Hs 17448 Homo sapienε cDNA FLJ13618 fiε, clone PL 643
426496 D31765 Hs 170114 KIAA0061 protein 643
422303 AW410382 Hs 27556 hypothetical protein FLJ22405 642
440119 AA865455 Hs 125331 ESTs, Moderately similar to unknown [H s 641
451658 AW195351 Hs250520 ESTs, Moderately similar to 138022 hypot 640
435918 AF263538 Hs 86232 growth differentiation fxtor 3 638
439979 AW600291 Hs 6823 hypothetical protein FU 10430 638
412220 BE350058 Hs 36787 chromodomain helicase DNA binding protei 638
436716 AI433540 gb tι69g05 x1 NCI_CGAP_Kιd11 Homo sapien 6 38
413703 BE158360 gb PM1-HT0383-131299 001-h08 HT0383 Homo 638
413326 H88621 Hε 19762 ESTs, Weakly similar to KIAA1140 protein 6 38
441970 AW959918 Hs73737 ESTs 6 38
430835 AI240006 Hs 192326 ESTs 638
414890 BE281095 Hs77573 undine phosphorylase 6 37
418113 AI272141 Hs 83484 SRY (sex determining region Y)-box 4 637
414768 AW376989 Hs 259855 elongation fxtor-2 kinase 636
422340 AW296219 Hs 115325 RAB7, member RAS oncogene family-like 1 636
407198 H91679 gb yv04a07 s1 Soareε fetal liver εpleen 635
432586 AA568548 ESTε 635
432729 AK000292 Hs 130732 hypothetical protein FLJ20285 635
420012 AW957965 Hs 99014 Homo sapiens, clone IMAGE 3632168, mRNA 635
432879 AW815932 Hs 173734 ESTs, Weakly similar to ALU1_HUMAN ALU S 635
429732 U20158 Hs2488 lymphxyte cytosolic protein 2 (SH2 doma 635
415082 AA160000 Hε 137396 ESTs, Weakly similar to JC5238 galxtosy 6 35
437296 AA350994 Hε 20281 KIAA1700 635
427747 AW411425 Hs 180655 seπne/threonme kinase 12 633
445873 AA250970 Hs 251946 poly(A)-bιndιπg protein, cytoplasmic 1-1 633
410387 AI277367 Hs47094 ESTε 633
413677 AW503116 Hs 301819 zinc finger protein 146 631
418458 AA332941 Hs 85226 lipase A, lysosomal xid, cholesterol es 631
443634 H73972 Hs 134460 ESTε 630
409453 AI885516 Hs 95612 ESTε 629
443035 Z45822 Hs 8906 Homo εapiens clone 24889 mRNA sequence 629
432841 M93425 Hε62 protein tyrosine phoεphataεe, non-rxept 6 29
410532 T53088 Hs 155376 hemoglobin, beta 628
428453 AB011110 Hs 184367 GTPase xtivatmg protein like 627
410597 W16518 Hs279518 amyloid beta (A4) prxursor-iike protein 6 26
458965 AA010319 Hs 60389 ESTs 6 25
419926 AW900992 Hs 93796 DKFZP586D2223 protein 625
426797 AW936258 Hs 342849 ADP-πbosylation fxtor like 5 6 25
412528 AI123478 Hs 32112 ESTs 625
410079 U94362 Hs 58589 glycogenin 2 6 25
427477 AW973119 Hs 178391 πbosomal protein L44 6 24
416297 AA157634 Hs79172 solute earner family 25 (mitxhondnal 624
435961 BE293127 Hs 283722 GTT1 protein 6 23
424090 X99699 Hε139262 XIAP assxiated fxtor-1 6 23
428311 NM.005651 I Hs 183671 tryptophan 2,3-dιoxygenase 623
451061 AW291487 Hs 213659 ESTs, Weakly similar to KIAA1357 protein 6 23
409731 AA125985 Hs 56145 thymosin, beta, identified in neuroblast 623
440129 AA865818 ESTs, Weakly similar to S71886 Ste20-lιk 622
428773 BE256238 Hs193163 bπdgmg integrator 1 6 20
436372 AW972301 Hs 310286 ESTs 6 19
440719 AA150869 Hs 26267 ATP-dependant interferon responεe protei 6 18
406685 M18728 gb Human nonεpxiiϊc crossreactmg antig 6 18
421305 BE397354 Hs 324830 diptheπa toxin resistance protein requi 6 17
450988 BE618571 Hs429 ATP synthase, H transporting, mitochondr 6 16
458659 AW749895 Hs 332520 Homo sapienε mRNA, cDNA DKFZp434A1014 (f 6 15
406806 AW088535 nbosomal protein, large, P0 6 15
420151 AA255931 Hs 186704 ESTs 6 14
413441 AI929374 Hs75367 Src-like adapter 6 13
449317 AW293413 Hs 132906 19A24 protein 6 13
421568 W85858 Hs 99804 ESTs 6 13 435919 AI052189 Hs 114104 ESTs 6 13
417353 AA375752 Hs 348140 Homo sapiens mRNA cDNA DKFZp586F1822 (f 613
448946 AI652855 Hs 23363 hypothetical protein FLJ 10983 6 13
432415 T16971 Hs 289014 ESTs, Weakly similar to A43932 mucin 2 p 613
406857 AA613726 Hs 29797 πbosomal protein L10 6 11
417944 AU077196 Hs 82985 collagen, type V, alpha 2 611
425095 AW014160 Hs 182585 KIAA1276 protein 610
435756 AI418466 Hs 33665 ESTs 610
431155 AW971213 gb EST383301 MAGE resequenceε, MAGL Homo 610
413813 M96956 Hs 75561 teratocarcinoma derived growth factor 1 6 10
451052 AA281504 Hs 24444 Homo εapienε cDNA FLJ22165 fis, clone H 6 10
450511 R07423 Hs 85092 thyroid hormone receptor interactor 11 608
447832 AI433357 ESTs 608
434421 AI915927 Hs 34771 ESTs 608
437438 AL359620 Hs 14217 hypothetical protein DKFZp762P2111 608
449625 NM 014253 odz (odd Oz/ten m, Drosophila) homolog 1 608
415912 H08859 Hs 206469 ESTs, Weakly similarto ALU6.HUMAN ALU S 607
433339 AF019226 Hs 8036 glioblaεtoma overexpressed 606
435511 AA683336 Hs 189046 ESTs 606
423458 AI204212 ESTs 606
442379 NM 004613 Hε 8265 transglutaminase 2 (C polypeptide, prote 606
457211 AW972565 Hs 32399 ESTs, Weakly similar to S51797 vasodilat 606
444621 AA298065 Hs 11465 glutathione S transferase like, glutathi 606
455263 AW961702 Homo sapiens cDNA FLJ14028 fis, clone HE 605
432925 AA878324 Hs 264750 ESTs 605
457752 AI821270 Hs 285643 Homo sapiens cDNA FLJ14364 fis, clone HE 605
449810 AB008681 Hs 23994 activin A receptor, type IIB 604
406797 AI432224 nbosomal protein L6 604
450157 AW961576 Hs 60178 ESTε 603
422134 AW179019 Hs 112110 mitochondnal πboεomal protein L42 603
407635 AW370213 Hs 295232 ESTε, Moderately similar to A46010 X-lm 603
453331 AI240665 ESTs 603
430504 H52761 Homo sapienε, clone MGC 12617, mRNA, com 602
444708 AW971049 Hε 11774 protein (peptidyi prolyl cis/trans isome 601
409945 AW015935 Hs 122642 ESTε 600
419641 BE170548 Hs 118190 Homo εapieπs cDNA FLJ21081 fis, clone C 600
453785 AI368236 Hs 283732 ESTs, Moderately similar to ALU1.HUMAN A 600
430387 AW372884 Hs 240770 nuclear cap binding protein subunit 2, 2 600
TABLE 52B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT Number Accesεion
438091 22448 1 AK054860AV652198AV652192AV652138AV652127AV652194 BE935919AV652017AV651995AV651548AV646063AV651985AV646184
AV646179 AW880409 AA345002 BF155189 BE068931 X56197 AL603014 AW953629 BM263546 BE550772 AA701084 AI681352 AA358689 AW938841 BF438147 W05391 H75313 BF326185 AV646335 AV651589 AV646340 AV651992 AV646384 AV646364 AV687497 BF155183
AV646370 AW797876 AI906821 X56196 BE833835 AA628440 BE833808 BF224205 AA709126 BE673807 AI923886 AA947932 AI276125 AI185720 AW510698 AA987230 BE467708 AW898628 AW898544 AI146984 AW043642 AI288245 AI186932 AI635262 AI139455 AI298739 AI813854 AI024768 BE699445 BE699444 AI707807 D52654 AI214518 AI004723 AI698085 AW087420 AI565133 AA845571 AW898622 BF110144 AW513280 AI061126 BF362770 AI268939 AI435818 BF475318 AI024767 BE174213 AA757598 AA513019 AA902959 AI860794 AI334784 BF108411 BM310532 AW513771 AI951391 AI337671 BF095606 BF095601 BF095468 AW890091 BF095753 AW243400 AW898607 AW898616 BF362762
AI922204 AW898625 BE699468 BE174196 AW102923 D52715 BE699456 D52477 D55017 BF955933 BG623563 AV646254 AA463522 BI003244 AI299190 W40186 BE174210 BF939091 BF434180 AW579001 T55662 H01811 T52522 BF945037 BF955938 D54679 D53933 R67100 BG925552 BF999056 R83430 Z29922 T85791 W03942 H63289 AI091537 BF086583 AA345570 H48870 H80720 T83523 BI039626 BI037700 R00353 BF155184 N98343 N79072 H01812 T55581 426295 51 OJ BE880923 BG390191 AW470082 AW014585 AI423255 BI714731 BG054894 AW780248 N31683 AW664132 AW467353 AI983152 AA617918 BF447795 AI088357 AA807328 AA576970 AI741153 AI755003 AI474016 AI422030 AI348114 AW997085 BM271753 AI363147 BM311311 AI146640 A1246771 AW512619 AI359020 BG054897 AI292234 AI215830 AI283836 C06205 AW503423 AW272680 N33205 AW873021 AA070724 AI753886 AW192487 AI087151 AA658909 AI346368 AI335677 AA825442 AW440066 AW131357 AW513210 AI082314 AI085455 BE551404 AA780704 AW008596 AI796964 AA917471 AI400531 AA668626 N72207 AI306482 AW440562 AI084687 AA347280 AA063536 BF477389 AI241662 AA931543 AA484310 AA812486 AI032216 AA665779 AI916336 AI350590 BF198106 AI433377 AI300638 A1672626 AI282741 AI351487 AW105544 AA973627 AW517914 AA715424 AA508454 BF334080 AI274618 AW367201 AW572619 AW469088 AA382095 AI368364 AI146934 AI357180 AI361181 B1911347 BI871044 AA136325 BF084010 BF084007 AA335788 AI920878 AA809614 BE932941 AI678261 C75308 AI148479 BE178174 W88513 BM013627 429978 35194 2 BE738425 BE738323 BM126944 AW629678 AW265195 AI916735 AI394255 AI573090 A1354442 AW612857 AI339558 AI919424 AI377532 AI354441 AI308821 AA772275 AW055215 AI589705 AI336532 AA806547 AV682125 H93575 AW071172 AW769904 AI863985 AW265018
AW196655 D79662 BE042393 N75017 AW014741 C75509 BE748621 H92431 AW079261 AW901780 AA329482 AW960115 BI260621 AI767525 R31663 BI918664 AW963196 C06195 A1678018 412636 1438.1 M77830 NIVL004415 AF139065 BG681115 BG740377 BI712964 BG000656 AA128470 BI438324 H27408 BE931630 BE167165 AW370827
AW370813 J05211 BG698865 BG740734 BG680618 BG739778 BI765807 BM353403 BM353248 AW177784 AW205789 AW951576 AW848592 BE182164 BF149266 BE940187 BI060445 BI060444 BF350983 BE720095 BE720069 BE715154 BE082584 BE082576 BE004047 AA857316
BI039774 BE713818 BE713548 AW170253 BE160433 BI039775 AW886475 BM462504 BE931734 BF149264 AA340777 BF381183 BG621737 AU127260 AW364859 BF993352 BG223489 BE819009 BF381184 BE715956 R58704 AA852212 AW366566 BI090358 BF087707 BE819046 BE819005 AA377127 BE073467 BE819069 BE819048 BI036306 BG990973 BI040954 BF919911 AU140155 AI951766 AI434518 AW804674 BF752969 BE837009 BE925826 BF149265 AW995615 BE814264 BI039782 AU140407 BE144243 BE709863 BF985642 BE001923 BF933510 AW265328 BG436319 BE182166 AW365175 AW847688 BE818280 AW177933 BF873679 AW178000 BE082526 BF476866 BF086994 BF592276
BE082507 BE082514 BE082505 BF873693 AW068840 AW847678 BF804153 AW365157 BE813930 BE002030 AW365153 BE184941 BF749421 BE184920 BF839562 BE184933 BF842254 BE698470 BE931048 BF999889 BF368816 BE184924 BE159646 BE714632 BE184948 BG986845 AA131128 AA099891 W39488 C04715 BF096124 BE865341 AW799304 AL603116 BE149760 BE705967 BE705966 BE705968 AW848723 AW376699 AW376817 AW376697 BG005097 BF751115 BE696084 AW848371 AW376782 AW848789 AW849074 AW361413 BF927725 BF094211
AW997139 BE865474 BE185187 BE156621 BE715089 BE713297 BE713298 BE179915 AW799309 BF872345 BF088676 BE705939 AW752599
BG005197 BF350086 BE715196 BE715155 BF752396 BF093817 BF831190 BF752409 BE006561 BG959922 BF094833 BF094748 BF094583
AW377699 AW607238 BE082519 AW377700 BF349467 AI190590 AI554403 AI392926 AU158477 BI467252 AU159919 AI760816 BF082516
AI439101 AA451923 AI340326 AI590975 BI791553 AI700963 AI142882 AA039975 AA946936 AA644381 BM314884 AA702424 AI417612
AW190555 AI220573 AI304772 AI270345 AI627383 AA552300 AI911702 AW166807 AI346078 W95070 AA149191 AA026864 AI830049 AW780435
AI078449 AI819984 AI858282 BI468588 AI860584 AI025932 AA026047 AA703232 AA658154 AA515500 AW192085 AA918281 T77861 AI927207
AI205263 BF082491 AW021347 AI568096 BE939862 AA088866 D12062 AA056527 AA782109 W19287 W02156 AW150038 AA022701 T87181
H44405 AI910434 BF082513 AI494069 AI270027 AI635878 AA128330 BG681425 BE706078 R20904 BG680059 BG676647 BF764409 AA026654
AV745530 BI762796 BG287391 AW798780 BE706045 BE926470 AW799118 BF087996 BE002273 AW879451 AI571075 BE067786 AV721320
AI022862 N29754 C03378 N84767 AA131077 H30146 BE714290 AI686869 AI568892 AI915596 AW105614 AI887258 AI538577 BE926474
BE067737 BG319486 AA247685 AW798883 AW103521 BF989173 AW860878 BE939707 BE185750 BE714064 BE713903 BE713868 BE713763
BG950164 BE713810 AW365151 BG955489 BE005272 BF915937 AW365148 AI905927 BF992780 AW853812 BG954443 BI770853 BG679406
BG740832 BG681087 BG698430 AA455100 T87267 BE696209 BE696210 BI089483 BEO06273 BE872225 AW391912 BE925515 BG677012
BG741970 AA026480 BE705999 BG677157 BE009090 BG681378 BE712291 BG961498 BG678984 BI040941 AA337270 AW384371 AW847442
BI058659 BE813665 W95048 W25458 AW177786 AA025851 BE931733 BF154837 BG949393 BE714441 AW996245 BE711801 AI284090
BE064323 BE719390 BE940148 BG991212 BF375714 BF349522 BG996267 T48793 BI013292 BE001925 AW365156 AW365154 AW606653
BF763109 BE931637 BE167181 BE713879 BF354008 BF678726 H90899 AW365145 W38382 AI498487
442562 39593 1 AK056685 BG399272 AA187835 BF821903 AV660550 AV660556 AV660502 BG564397 BE379584 BF446961 AI653056 AW973709 AI653173
BG054997 AI266043 BI054879 AI656750 AI492830 AW021142 AI472184 AW170056 AI082443 AI167921 D59940 BI492088 H74180 AW130886
AI348677 AI278577 AA761517 AI698203 AA115535 AI264790 AW205074 AA860452 AA554902 AI000715 D62102 BE544768 AI376090 D59939
AW242249 AA525421 R34211 R34328 BF248064 BF241437 BF572759 BF218832
413787 7612J BC003047 S80794 NM.003405 X78138 AY007132 L08439 AW340648 AW131665 AI082748 AI470204 BI711078 BF350700 BI496963 AI087141
AA720684 AA862331 AA605146 BM313650 AI089749 AI359738 N69107 AW995424 AI086917 AI083995 AW340217 N99662 AI829449 AI089839
AI608761 AI342365 AI199076 AA908944 AI248943 AU160053 AI191245 AI218477 AI077943 AA864930 AI310394 AA872478 AI279782 W61343
AA565955 W46596 AA126874 AA223241 AA491574 R84813 AA491520 BG055114 AI469689 BE464590 AW664539 H67097 AL534332 C21397
AI085941 AW028427 BG939820 AI697089 AI039008 AI125315 AI655561 AW150042 L20422 X57345 BI458375 AU142852 BI666601 BE888276
AU119302 BI603754 BG705953 BI598754 BE296713 BG002538 BF9519 1 N29226 BE909424 AV698274 AV683116 AV708195 AA127798
AI124697 D54224 F08031 AA340253 BF923383 BM467808 BI546644 BG777200 BG705941 BG468577 AU127209 AW403970 BI597630 BI458091
AV689560 BI669267 BG506219 BI837163 BI667275 AA343750 BE783112 BF671405 BF954720 H67636 H69456 AA484894 BI869271 BF998207
N31547 BF945817 BF947918 N90630 BG980194 AA156681 BI493502 AW273118 AI473820 AA608688 AI359337 AV712091 AA084101 BF592036
H13301 AI864305 AA505883 AI423963 AW084401 AI917740 R69858 AA033631 N79982 BE885276 AI635674 AA096126 AA700018 AV707753
AI082545 AU145681 AA629032 AI421367 AA740589 AA150830 AI248541 AA988608 AA150478 W65437 BM310234 AA262704 T28031 AI811116
BM272753 H21979 T15405 AA938406 F04963 AI188296 AW152629 AA905196 BG223058 AI831016 AI766457 AI811102 AA776573 AI922133
AA775958AI261476AA219489 AI688035AI872093 BE537084AW189078 D82630AI123121 AL583492 BE350791 R69901 W65436 BE155392
BI089081 BE155394AL120538AW166100 AI359620AI174338 N20527 W47413 AA155615 A1272249 H25293 BE614558 H69864 AW383484
H78021 H11617 R56892 H23204 N21530 R82499 AW383522 AA774536 AL534331 W94127 W46459 A1866231 AA513281 AA192465 H69844
W85827 AW383642 AW383529 AA171496 AL537424 BE814866 BF823254 R82553 AI809817 A1559406
410143 MH1244_8 AK000357 AI571830 AA579613 AA668790 BF939495 BF196886 AI990982 BF591561 AI809189 AW410232 BF739769 A1144392 BF438721
AI707495 AI423359 N52503 BE855784 N94367 AI023931 AA563662 AI744624 AI221298 AI299523 AI299520 BI491312 AI452711 AI360730
AA622643 AW195955 AA470473 AW392767 AI218127 AA873430 AA906005 AA748160 H89523 AW020252 AW664988 AA970424 AA879079
AI581622 AI361357 AA468498 AW008694 AA903275 AI187724 AI187718 AA890505 BF092771 AI066655 BE714172 BG289028 AW080390
BE001197 BF132049
450377 12109.1 AB033091 AL520743 BE811813 N53332 N99716 AL561910 AA280655 BE710392 AV705100 AW293978 AW444556 AA281459 AI679751 AI873695
BG700891 BI553517 R80518 BG779771 BG534451 AA479402 AW961580 BF061430 AI857643 AI768486 AW512118 AA479302 AW770384
AW072470 AI041596AI049699 AW592865AA976261 BE879747 BG114119 AW183811 AA909938 BF571621 BF350794 BF351375 BE925699
AL050294 BC010371 BF982270 AL042656 BF095732 AW812618 BF095731 BG212397 BF678765 BI038602 BG388664 AW675337 BG289398
BE939598 AW805570 AA527097 AW150540 AI693720 AA743364 AI915793 N48185 AI573107 AA043474 AI351615 AI969490 AI910763 R50866
AI699181 N73808 H08164
425996 138046.1 BM006551 AA367152 AW953705 AI631833 AW237429 AW027804 AA729038 BE503409 AI521935 BF739953 AA702982 AA557633 AA780065
AI218139 A 194264 D20120 AI082715 AI969980 BE857686 BE326711 AW953706 AI393749 AI383821 W67199 AI431759 AI796526 AI521794
AI796380 AW117545 AI749657 AI537634 N50122
427521 513212.1 AW973352 BF222929 AW016853 BF059130 A1651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 AI206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892 444060 6315.1 AK055070 AK055612 AK000174 BG619806 BG108086 AI741949 AI004176 BF891936 BF378565 AW197163 BE856860 BE245124 AW674411
AA490531 AW674981 AA740788 AW274758 BF512523 AI521278 AA548759 AI802431 AW051682 AI628247 AI799606 AW088103 AA236549
AI191529 AW273168 AI168451 AW073812 AW090611 AW003593 AI215845 AI799616 AW474940 AA954927 BM193740 AW662704 AW090127
AA969444 AI080438 AA552500 AW237538 AA481060 AI246378 AA565227 AA398921 AA207051 AA721378 BF438608 AI086295 AI886630
AA904112 AI864588 AW271985 AW078868 AA725342 BF326598 AA843572 AI082536 AA766664 AI453279 AA435673 AI619515 AA879080
AA234592 AA890223 AA766824 BI259822 AA393631 AW968840 BE940639 T83865 BE762742 AW897470 W05809 N41323 T87376 R68544
H88711 BI087136
409208 10117.2 AK074047 AI144342 AW014280 BM145128 N28267 AW206231 AA989041 H93197 AW594063 BG236296 AW236606 AW081031 AA765843
BM144372 AA989341 AI824838 A1963970 AI637671 AW196330 BG427526 BM148789 BF893644 BF881946
413497 1518002.1 BE177661 H06215 BE144709 BE144829 434280 14749041 BE005398 AA628622 AA994155 450139 340171 AK001838 AU135179 AU134241 AV651702 AV650032 AV651304 AV650101 AV651263 AV651888 AV651866 AA628554 AV651355 AV651174
AV651172 AW856145 AU117599 AU135386 BG254665 AA166919 BG483981 AW809606 BG494194 AA622811 AI676156 AA687804 AI701729
AU133725 AW961387 AU144387 AU151757 AA551031 BE675412 N34769 AA713483 AI890079 AI588918 AI361889 AI209020 AA668981 AI240990
AA741144 AA490899 AI200221 AW589574 W96201 BG154182 AV655159 AA328145 N36348 AI081357 N76715 AA693346 AA742488 AI269719
AA897483 AI886459 AU155873 H04255 AW243986 AA557749 AI286227 R68691 R33453 AW388097
430068 1177709.-2 AA947566 434442 111738.1 AA662701 AA633929 AA737415 438089 22448.4 BM475665 BE644917 AW770789 AW952971 N64863 BM263259 AI224545AI184866 N69114AW518902AI440169 AA809472 AV654440
AA281642 AU185230 AW337382 AI872923 AI537113 N73882T83378 H63731 BF671764 AW897824 A1811204 AA344646 BE009112 BG899664
H91240 R60548 N41701
451129 1495511.1 BE072881 AI762181 BE072946 414405 112689.1 AL047596 AA393792 AI670731 AI037957 AW874364 AI038137 N62286 AI241379 BE501096 AW090696 AI927369 AI669226 AI369437 AI371075
AW612409 AI686711 AI183289 AA477717 AI076122AA635190AA700984AA781508 D81020 BF575223 AI356183 D79312AI375558 H61111
BG283489 BE090666 BE090664 BE090662 H26545
422960 11862.2 BF090249 AW954947 AW890487 AI305236 D60845 D60537 AA825429 W36294 AW890410 AW088235 BF740240 AA448709 AI350279 AA879119
AA319510 BE702077 BE699015 BE702046 AW901293T99319 D81708 BF475488 D60383 D81751 BE699260
410730 114639 1 BG427950 AA826016 AI903441 BG939868 AW979154 AA640872 BG547134 AA457091 AW368860 W88852 R94779 AA088823 422689 874209.1 AW954733 AA315006 AW856665 438980 917280.1 AW502384 AA828822 AI982587 442495 928718.1 A1184717 AW518883 AF121173 425284 3834.5 BM476120 BE672181 AI697653 AA938187 AI280879 AW340123 AI912727 AI081775 AI089556 AI191349 AI871604 AI631607 AI890800 AI701917
AW771624 AA663041 AI991576 AI160622 AA771763 BE089784 BE089788 A1222942 AW418516 AA329211 AI095736 BE550294 AA738345
BE218683 BE670548 BG149505 BF061776 D19821 BE005786 BE178892 BE005728 BF841237 BE005648 R27634
441623 3362.1 BC022413 BE395396 BF754175 AA506621 BE706665 BE706678 AA723159 BE153169 BE706729 BE706558 BE153312 BE706706 AW371853
AW371849BE153241 BC017410 AI337912 AI090244 AW090300 BE219837 A1623661 BE501576 BE501734 AI742232 AI023964 AI458424
AA975373 AI288904 AI984583 AA890325 N32562 AI358102 AW241694 AI038448 AI672071 AI018389 AA576391 AA977874 AW189392 W37448
AA612894 AI277548 H89551 AI699774 H89365 AA315805 AW579186 BC014584 BC014581 AW780125 AI672414 BE328145 AW600919 BF031306
AW172758 BE708322 AA345675 BE875779 H28241 H25318 BF540913 BG179688 BF110202 AA528775 W37573 BE041644 AW366504 BM129522
BM129822 AI122760 BE718200 AW887496 AA149420 BE706307 BE539395 BE748765 AI373653 R75904 BF979185 BF691393 BG495595
BI094458 BE706702 BG496559 BF248373 BG494800
445493 4234561 AV711317 AI809938 AI808768 AI240593 AI915771 432666 144.7 AA558585 AA565499 AI360576 AW204069 AA991648 AA864939 430915 1978441 BG425760BF997600 N48516W73454 BF816344 BF997601 AA488953 425913 4123.2 AV703649 AW959818 AI582119 AI523459 AI674473 AW663543 AA825476 AI935231 BF742805 AA426156 AI253626 AA846477 AI024230
BF221780 AI493027 AW006841 AA814699 H99650 AI088977 AA442691 AI783526 BF207915 AI752847 AA782635 AI978980 AA788634 BG119454
BF678528 AI627829 BG993975 AV701283
438962 195763.1 AI207343 BF813684 BF928775 AA828585 406870 0.0 AA075144 406819 0.0 AA908472 447197 2176805.1 R36075 R36167 A1366546 418336 58817.1 AW969583 BI772505 BE179578 AI493714 AI937718 AA663709 BI868925 AW138743 AI911314 BE645538 BG911947 AI380325 AI265803 W56175
AI658779 AI675997 AW665991 AI459263 AI420121 Z38874 AA570115 AW301008 AA216257 BF062662 BI772789 H05989 BF085523 BI001277
424677 2518.37 U09414 NM 003438 AA503545 AI022449 AA043458 AA766074 AA765442 AA805052 AI028211 AW609708 419970 13569.1 AK055270 BE348291 AI190289 AW612022 AI269506 AI266578 AI269675 AW271406 BE879851 BF574163 BI497126 AW903775 BI917368
AW150900BF244813 H79201
433891 647290.1 AW182329 AA613792 T05304 AW858385 415995 2117.1 M95678 NM.004573 AL530754 AI439623 AW374413 BF898880 AW630959 BF875526 AW402206 BF818690 BF893068 AW504110 AW408049
BG002913 AL530753 AI524064 AW769231 AA464970 AA293723 AI095051 AI953375 A1982938 BM146050 AW575804 AA962489 AI655426
BM146046 T28538 BE241936 T89023 BI910963 AI416986 AI767111 AI422290 AW468260 BE676853 AI656771 AI961755 F04675 AA682826
AA737606 BM194382 AA912021 AW183098 BE676682 AI962227 AI591366 AA621765 AA293724 R51642 F10194 BI909727 BF892632 AW950600
AW950138 BG258587 BF892649 AI800647 BF892710 AA353176 BF894726 AA465038 BI040869 BI837749 BE244320 H18054T74300 AW797026
AA926790 F32814 AW751282 AI933994 AA578823 T78372 BF899896 BF882808 BF974969
451653 MH115364.1 BG119563AW975776 BG498478 BE245304AW450934BF508792AA599489AA599477 AI805268AA055489AI128758AA761425AA731858
AI302271 BE219432 AA687294 AA018972 AW629429 Z45675 AW961626 T30940 R34554 T84712 BG986694
436812 659779.1 AW978773 AW298067 AA810101 AW194180 AA731645 AI690673 418259 133853.1 BM310925 AA426110 B 310629 BF434286 AW015091 BF475996 AW118867 BE675186 AI688568 AI453594 AW590589 AI652425 A1827969
BF056946 AI802866 AI393380 AI476224 AW590639 AW136271 AI458252 AI524726 AA843768 AA782158 AI336058 AI097532 AW451563
AA459408 AA459633 AA418444 W23607 BG940150 AI493445 AW054729 AI221929 AI868744 AA215405 AA766713 AA621546 BF928317
BE464132 AI990909 AW271459 AI262061 AA215404 N74332 BG940151 BG952261 AA972115 W96315 AA689586 R69057 BF766886 BE769254
W05240
433162 2167905.1 A1742311 AI025842 AA578843 434372 858779.1 BG622121 AA631424 AA988296 AA631373 456629 207 22 AW891965 AW604749 BE080872 R15559 BE177623 AW883520 AW945343 AI246167 T07082 AW805679 W96278 AA135796 W32615 AW995418
AW801688 BE003837 AW801621 AW385721 AW385742 AW385714 AW604757 W87409 AW604738 AW385757 AW580796 AW801247 BE003239
BE003183 AA847112 AW580975 AW604760 AW385727 BE164590 BE003090 AW362791 AW604759 AW866589 AW604758 N44337 AI378548
AW890438 AA077172 AI288683 AA229639 AA091945 AW945454 AA063629 AA702504 AW861938 AW894816 AW580841 AA094372 T06399
AW885686 BE244086 BE005035 AW861913 AA551773 AW858460 AW370926 AW754352 AW889695 AW384408 AI907428 BE067491 AW861939
AA248197 AW381373 AW177325 AW806879 AA935217 BE067498 BE083742 BE067470 AW894935 BE082529 AI248811 BE179917 BE002200
AW607506 AW392889 AW894560 AW381360 AI904206 AW863533 C00609 AW381372 BE082530 AW898120 BE075323 AW392799 AW601420
AI695314 BE083790 AW858568 AW945550 BE177153 AW970506 BE350419 AI906919 AW360794 AI906917 AW885979 AW794240 AW945566
AI688683 AI688694 AW009660 AW601421 AW360793 BE066524 BE083901 AW369847 AW381871 AW935435 AW664582 AW877775 AW838449
BE180466 AW858501 BE180464 AI371163 AA778231 AI174991 BE011720 AW877776 AW877800 AW877795 T19900 AW866365 AW898099
BE011715 BE167842 BE011718 BE011724AW363639AW878658AW878662AW894887 BE082356AW389211 AW804286AW610312AI904717
AW610318 AW996909 AW610296 AW901923 AW880003 AI762171 AW062582 AW368713 AW062593 AW176663 AW842064 AW842089
AW842095 AI243049 AW902074 AW062592 AW176664 AW751692 BE087703 AI907439 BE009686 BE172115 BE077030 AW608556 AW835577
AI909628 BE077029 AW176241 BE077552 BE160370 BE160288 AW835656 AW606765 AW606770 AW835678 AW606758 AW606778 AI907484
BE172821 AW606768 AW999517 AW844165 BE171738 AW751683 AW610493 BE177484 BE177487 AA090510 AW844117 BE173367 AW999878
AI124870 BE163472 AW841823 AW379762 AW893297 AI290296 BE089132 AA610287 AW176676 AW607622 BE172639 AW893232 AA329629
BE089008 BE178350 BE178214 BE063291 AW820236 AW999653 BE089486 BE173126 BE171775 BE185787 AA558280 AI174840 AW999112
BE218391 BE172734 BE178021 BE172738 BE173324 AW603494 AL036722 R38192 R60905 H53721 H41052 AL037917 R37795 AW998972
AA767189 AW044272 H50689 AA768399 AA767764 AI087888 H44202 BE222792 N90597 W81396 N90615 AI935353 BE501168 F10945
AW118215 AI970480 AI627641 AW236081 AA574090 AI627652 AI681913 AI759983 N69591 N69276 BE467722 AW392780 BE172467 H92861
AI524921 F02989 Z39328 F02705 F01414 T88678 AI215165 H87220 AW374781
430283 1418.1 BC013728 BI084032 BF090365 BE410706 N36391 W80436 BF813124 R90857 R62778 H00591 H02329 AA355285 AK0008268C008721
BG744004 BG479141 BG823656 BG479061 AU121103 AU138176 BG702567 BI599840 BG422775 BG700944 BE280747 AU138529 BE269929
BG704110 AU123329 AU122058 AU138135 BG723106 BG722291 BG831041 BG705239 BE740517 BE207133 BE252867 AU139772 BG714385
BF568538 BE304393 BF971755 BE267965 BE272012 AU135396 AU124535 BI551682 BG700612 AI815488 BG475195 BE388273 BE391517
BM148991 BF929247 AV653435 AW250299 AW249189 BF093150 BF093173 AW205325 BF057101 BF000551 AI341108 AL162009 AK026136
BE907957 W73238 BI711467 BG926027 AI816428 AA837518 AI754405 BG179142 AA481485 AW023435 BE855747 AI885101 N52163 AI016096
AI090204 BE677045 AI523320 AI126855 N26501 AA043680 AA976459 AI039590 AI937917 AI361000 W94866 AI375797 AI079801 AI168236
AA599882 AA084368 AI342635 AI190294 N26093 AI085234 AI298169 BF939715 AI223164 H98704 BE218925 N29394 AI918735 N41520 AI147784
AI918796 AA854317 N22193 AA199850AI149728 AA121263 AI051074 AA565116 AI097349 N22209 AA552917 N33151 D52422 BF477483
AA476599 AA525787 AI279198 D53353 AA738063 AA558406 BI496334 AA999948 AA425847 BI496335 AA909624 BF197591 AW023259 AI652819
T31424 AA088213 T31115 AI206650 AA976796 AI948989 AW248762 AA449265 AA290687 AI682521 AA310227 Z38743 AA935369 AW119141
BF941087 AI470657 AI349451 AW079338 D45665 N21640 T30071 AI446705 R60220 BE833481 R49680 R70049 R41223 R32402 R69984 R70111
BM476906 BE293615 BE382443 BF155692 BE720638 BE931983 BE720594 BF085890 AA336953 BF081638 AA359915 AA384116 AA360142
BI667664 BG823235 BE315559 BE301958 BE891114 BG826267 BE253680 BG979094 AV722757 N67629 BG997927 BI915769 BG680692 R62777
BE251116 H56358 AW369586 BG677759 BI044604 R75787 BE770960 H69529 R69983 AA259238 R97827 AA310379 W01103 AI873384
AL554578 BF038102 H87182 H87517 H01574 T52573 N28881 AA301397 T92375 R68401 AW800466 AI268172 BE876949 D54019 AI909769
AW798415 BI222383 AI393171 C15260 N26959 H17129 T53095 T52494 R68602 AI364765 BF687869 AI817035 AW105354 BE293820 H14206
BI093066 C14063 AL534349 BE255883 BE254088 AA428399 AW579360 AW579381 N53144 D60748 D54020 BG292106 H96705 D52423 T36174 D54161 R73016 D55021 BI857200 H83444 BI016954 D54163 R15563 BI818664 BE152207 BI048502 BF885667 BE613212 BE165773 BF149332 AW607045 BE305200
430968 1237115 1 AW972830 AA489820 AA527647 AA570362
444207 9172.3 BE739425 AA514221 AA865491 AI828293 AA470456 AI276739 AA169357 BE932464 AA514889 AW819039 AW819083 BE843048 AI432496
AI470335 AI247243 BG533994 AA513783 AI887309 AA528036 AW972006 AW873028 AI924914 AI818810 AW152378 AW084946 AI521413 AI669583 BE932521 AI581370 BE180238 AW089750 AW771461 AW089714 AI590949 AI819148 AA731056 BF815234 BF911506 AA235803 AA485373 AI735658 AW393133 AW073080 AI707637 BF353320 BE843111 AW819036 AW393135 BG697291 AV648670 AV654332 AV687530 BG566964 AI807430 AI676072 AA837010 AI452482 AI625817 AW241750 BE048616 AI290928 AI680714 AA485530 BE175687 AV648513 AW130312 AI000556 AA632893 BE674169 BF001208 AA948166 BE175650 AA524664 AA490345 AI244948 AA602956 AA483492 AA918178 AW802049 BG675859 AV658871 BG678060 AI565004 AW819026 BE843092 AV686437 AV723049 BG616948 AI911647 AI743490 AI091096 BE857251 AI962074 AA040027 AW769317 AA343477 AA640112 BF876213 R82948 H26425 H82876 BE843095 BE843140 BG536641 BG617830 AA235802 BE774985 BE006682 BF342375 AA903144 BF338083 BF984258 AV657996 AI749532 BE768614 BE857252 BE932516 BE768573 AV657993 AV657777 AV752631 BE774974 T55847 BF095761 BF911511 BE710793 BE180119 BG617338 H45942T55897 AV657718 BG563497
418905 517 1 B 469076 AA533027 AI127512 AI368802 AA533141 AA700560 A 576028 AI610851 AI435361 BM129172AW474544 B 128899 AI814292
AW502039 AA531243 BF941858 AW502037 AA702337 AI419854 AA662755 AA934364 AI300510 AI291136 AA505263 AI144527 AI076919 AI633534 AI242473 AA938561 BG055372 AA512894 AI671356 AA962403 BF808010 AA663911 AA847056 AA513301 AA369069 AA377265 BG291206 AA402298 AA885766 AW801002 AA302290 AI305842 AW800873 AA302492 AA478427 AI817291 AW801104 AW801028 AA865744 BF155979 AI374743 AA478431 AI159846 AI369757 AI800672 BF435788 AA255451 AI937707 AW006198 AI280363 BF062434 AW801115 AI919181 F28413 W04214 AW152380 AW901567 AW901570 AA886371 AA384251 AI302846 BE701902 AA931606 H42673 R33703 AW901556 AA009816 AW901568 AW352200 AA256558 H15928 BI087170 AW800530 AA369068 N98562 H28652 N34644 H97650 H00956 W70039 AI142831 AA009817 F37136 N70289 AA531347 R72374 H27488 R66605
436716 2472838 1 AI433540 AA804981 AA728984 413703 376077 ? BG015794 BE158357 BE158353 BE158358 BE158360 BE158352 BE158351 BE158355 432586 6633 1 BC022881 AU150944 BG750783 AW754175 AW857737 AI911659 AI050036 AA554053 AI826259 AA568548 440129 2607882 1 AI732997 AA977633 AA865818 406685 0 0 M18728 406806 0.0 AW088535 AI889321 AA954221 AI337552 R42581 AW194670 AA064862 AW001147 AA864374 AA630699 AW276176 AA676615 AA857965 AI625428 AA580792 AA582038 AA581668 AA658065 AA828156 AA857160 AA936103 AI149335 AA936925 AA581684 AA954198 AW238461 AI281504 AI265812 AA583267 AW236162 AA876535 AW304286 AW474334 AI559415 AI589241 AI660952 AA641137 AI431696 AI688844 AA552513 AA564954 AW090553 AI205612 AI245753 AA954883 AA947909 AI866014
431155 1235742 1 AW971213 AA493925 AA493567 AA876839 AA934462 447832 1036795 1 A1628543 AI433357 AW772732 449625 249224.T BI918168 AW779760 N48674 AI375997 AA235370 BG699146 AI913631 AI498402 AI016320 AA323193 R49021 D59344 BG986750 N45526 BG986917 T61382 R49391 R45432 AI203107 R35004 F07491 R25094 R35360
423458 30480.1 BC018070 BG702493 AI204212 AA460929 AA993606 BF926635 AA226938 BG190705 BG186496 AW291865 BG183340 BG195301 BG214539 BG215094 BG198867 BG196332 BG208220 BG212418
455263 26143.1 BG216963 BG164885 BG213710 BG204771 BG193014 BG197556 BG217481 BG198185 BG183594 BI596425 AA115605 AI589156 BF439839 BG188832 AI359615 BG190473 AI024233 BF439574 AW118065 AI672797 AA610042 BG212008 AI204382 R70913 AA033534 AA781036 AI627278 AA307285 AA034218 BG482749 AW162429 BI602460 AA721969 AA476516 AA476416 AA903019 BF110864 AA307286 AA115471 AW964555 AA423826 AA115129 AI419107
406797 0 0 AI432224 AW276890 AI499346 AA937014 AA653573 AI318525 AI246219 AA961591 AI270640 453331 16559.1 BG571303 AA410586 AA035018 BG572117 BG620022 AA147247 BG005785 BG014448 R31981 H02668 H12498 R36203 BF992089 R73999 T49904 R75732 BI057974 T53681 AA147933 N50695 R68588 R25671 R31935 R25110 R36105 AK055628 BE157467 AW663674 AA190993 H01642 BF510304 AA626915 AA746952 AI161014 AA099554 BG572534 AI803329 AI809932 AI808765 AA411449 AI378760 AA976929 AI378620 AA909684 R75632 AI360919 AI350463 AW069127 AA411621 AA742532 H12451 BE208298 H03612 H12839 N58781 R75957 BF996484 AI240665 BF989591 BI056086 BG001590 BF107035
430504 5477.6 BE219720 BF475241 AI571723 BE219848 BI789268 AI224899 AA724864 AW771467 AA480255 AW845616 AI440295 H52800 BE218790 AI681575
AW300064 AW262133 H21568 AI363015 AI884914 H86948
TABLE 52C
Pkey Unique number correεponding to an Eoε probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA εequence of human chromoεome 22" Dunham, et al (1999) Nature 402489-495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
402474 7547175 Minus 53526-53628,55755-55920,57530-57757
402145 8018280 Plus 113086-114800
401091 9958240 Plus 94760-94898
401466 6682292 Plus 28748-29023
406542 7711499 Plus 117335-118473
401113 9966541 Minus 19419-19959
405086 8072509 Plus 73664-73841,74081-74217,74610-74779,7492
TABLE 53A
Pkey Unique Eos probeεet identifier number
ExAccn Exemplar Acceεsion number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title R1 Ratio of testicular cancer (non-semmomatous and semmomatous) compared to normal adult tissues
Pkey ExAccn UnigenelD Unigene Title R1
432666 AW204069 ESTs, Weakly similar to unnamed protein 7820
452838 U65011 Hs 30743 preferentially expressed antigen in mela 7545
418696 AW959433 Hs 326290 hypothetical protein FLJ12581 5880
432730 AI066520 Hs 131358 ESTs 51 80
450581 AF081513 Hs 25195 TGF-beta 4 4840 426534 U58096 Hs.2051 testis specific protein, Y-linked 44.05
423458 AI204212 ESTs 36.60
428664 AK001666 Hs.189095 similar to SALL1 (sal (Drosophila)-like 34.65
420367 AA259090 Hs.257028 ESTs 32.60
451106 BE382701 Hs.25960 N-MYC oncogene 30.10
437052 AA861697 Hs.120591 ESTs 29.35
417407 AA923278 Hs.290905 ESTs, Weakly similar to protease (H.sapi 29.05
420759 T11832 Hs.127797 Homo εapiens cDNA FLJ11381 fis, clone HE 28.45
420347 AL033539 Hs.97124 Human DNA sequence from clone RP1-309H15 28.25
407710 AW022727 Hε.23616 ESTs 26.86
448981 AI968719 Hs.195387 ESTs 26.40
429486 AF155827 Hs.203963 hypothetical protein FU 10339 25.55
420528 AF130728 Hs.98586 doublesex and mab-3 related transcriptio 25.10
425769 U72513 Hs.159486 Human RPL13-2 pseudogene mRNA, complete 23.70
430252 AI638774 Hs.105328 testes development-related NYD-SP20 21.95
454077 AC005952 Hs.37062 insulin-like 3 (Leydig cell) 21.73
428227 AA321649 Hs.2248 small inducible cytokine subfamily B (Cy 20.15
434649 AA738254 Hs.165390 ESTs, Highly similar to A40350 transcrip 19.65
424578 AK001973 Hs.150890 hypothetical protein 19.16
427335 AA448542 Hs.251677 G antigen 7B 19.05
438915 AA280174 Hs.285681 Williamε-Beuren εyndrome chromoεo e regi 18.95
432938 T27013 Hs.3132 steroidogenic xute regulatory protein 18.86
449322 AI638616 Hs.196566 ESTs 18.30
430691 C14187 Hs.157208 aristaless-related homeobox protein ARX 18.00
430676 AF084866 gb:Homo sapiens envelope protein RIC-3 ( 17.96
440119 AA865455 Hs.125331 ESTs, Moderately similar to unknown (H.s 17.41
418756 AA252254 Hs.226949 ESTε 17.20
410102 AW248508 Hs.279727 ESTε; homologue of PEM-3 [Ciona εavigπyi 16.20
447534 AW953935 Hε.288655 ESTε 16.04
407122 H20276 Hs.31742 ESTs 15.95
446979 AI654443 Hs.197683 ESTs 15.90
406547 Target Exon 15.70
427711 M31659 Hs.180408 solute carrier family 25 (mitochondnal 15.65
456847 AI360456 Hs.37776 ESTs 15.50
448776 BE302464 Hs.30057 MRS2 (S. cerevisiae)-like, magnesium hom 15.00
452291 AF015592 Hs.28853 CDC7 (cell division cycle 7, S. cerevisi 14.95
408908 BE296227 Hs.250822 serine/threonine kinase 15 14.65
418007 M13509 Hs.83169 matrix metalloproteinase 1 (interstitial 14.20
422828 AL133396 prion protein 2 (dublet) 14.08
433330 AW207084 Hs.132816 hypothetical protein MGC14801 14.05
410561 BE540255 Hε.6994 Homo sapiens cDNA: FU22044 fis, clone H 14.05
427667 AK001279 Hs.180171 Homo sapiens cDNA FU10417 fis, clone NT 13.90
418134 AA397769 Hs.86617 ESTs 13.85
454438 AA224053 Hs.172405 cell division cycle 27 13.70
449032 AA045573 Hs.22900 nuclear fxtor (erythroid-derived 2)-lik 13.40
426427 M86699 Hε.169840 TTK protein kinase 13.35
437789 AI581344 Hs.127812 ESTs, Weakly similar to T17330 hypotheti 13.20
419384 AA490866 Hs.39429 ESTs 13.10
418477 AW022983 gb:df46h12.y1 Morton Fetal Cxhlea Homo 12.85
453922 AF053306 Hs.36708 budding uninhibited by benzimidazoles 1 12.80
447188 H65423 Hs.17631 hypothetical protein DKFZp434E2135 12.78
430521 NM.016383 Hε.242183 HOM-TES-85 tumor antigen 12.72
443068 AI188710 ESTε 12.65
437099 N77793 Hs.48659 ESTε, Highly εimilar to S14458 laminin a 12.60
420401 AK001907 Hs.97464 hypothetical protein 12.50
410361 BE391804 Hε.62661 guanylate binding protein 1, interferon- 12.50
431494 AA991355 Hs.298312 hypothetical protein DKFZp434A1315 12.45
406937 U14622 gb:Human traπsketolase-like protein gene 12.25
439451 AF086270 Hs.278554 heterxhromatin-like protein 1 12.10
404996 Target Exon 11.86
424905 NM 002497 Hs.153704 NIMA (never in mitosis gene a)-related k 11.85
444619 BE538082 Hs.8172 ESTs, Moderately similar to A46010 X-lin 11.60
434551 BE387162 Hs.280858 ESTs, Highly similar to A35661 DNA excis 11.55
421241 X91817 Hs.102866 tranεketolase-like 1 i 11.50
414972 BE263782 Hs.77695 KIAA0008 gene product 11.45
426866 U02330 Hs.172816 neuregulin 1 11.37
433159 AB035898 Hs.150587 kinesin-like protein 2 11.35
433800 AI034361 Hs.135150 lung type-l cell membrane-assxiated gly 11.24
440207 AI371978 Hs.128326 ESTs 11.12
407276 AI951118 Hs.326736 Homo sapiens breast cancer antigen NY-BR 11.10
450142 AW207469 Hε.24485 chondroitin sulfate protxglycan 6 (bama 11.05
449576 AW014631 Hs.225068 ESTs 10.95
414251 AL042306 Hs.97689 VASA protein 10.95
422956 BE545072 Hs.122579 ECT2 protein (Epithelial cell transformi 10.90
436812 AW298067 gb:UI-H-BW0-ajp-g-09-0-Ul.ε1 CI_CGAP_Su 10.85
427521 AW973352 ESTε 10.81
408728 AL137379 Hs.47125 hypothetical protein FLJ 13912 10.80
442832 AW206560 Hs.253569 ESTε 10.62
436899 AA764852 ESTε 10.60
428949 AA442153 Hs.104744 hypothetical protein DKFZp434J0617 10.55
409731 AA125985 Hs.56145 thymosin, beta, identified in neuroblast 10.45
435206 AI432364 Hε.160594 ESTε 10.15
433975 AA971953 Hs.122055 ESTε 10.10 446791 AI632278 Hε 195922 ESTs 1005
422232 D43945 Hs 113274 transcnption factor EC 1000
420047 AI478658 Hs 94631 brefeldm A inhibited guanine nucleotide 971
434334 AA912476 Hs 116750 Homo sapiens cDNA FLJ 13221 fis, clone NT 950
423673 BE003054 Hs 1695 matrix metalloprotemase 12 (macrophage 944
438188 AA779975 Hs 128859 ESTs 9 30
418973 AA233056 Hs 191518 ESTs 925
413627 BE182082 Hs 246973 mtron of Bicaudal D homolog 1 925
422689 AW856665 gb RC3 CT0297-290100 013 d03 CT0297 Homo 9 15
436608 AA628980 Hs 192371 down syndrome critical region protein DS 9 11
434699 AA643687 Hs 149425 Homo εapiens cDNA FLJ11980 fis, clone HE 908
426518 Z43039 Hs 170198 KIAA0009 gene product 905
440968 N36327 gb yx82b06 r1 Soares melanxyte 2NbHM Ho 905
440952 AI291804 Hs 118101 ESTs 905
427469 AA403084 Hs 269347 ESTs, Weakly similar to 2109260A B cell 9 05
442618 R56222 Hs 26514 ESTs 896
419423 D26488 Hs 90315 KIAA0007 protein 895
428153 AW513143 Hs 98367 SRY (sex determining region Y) box 17 (S 8 80
439979 AW600291 Hs 6823 hypothetical protein FLJ 10430 876
444971 AI651116 Hε 148659 ESTs 875
436513 AJ278110 Hε 125507 DEAD box protein 8 60
427486 AA974433 fibroblast growth factor 4 (hepaππ sxr 859
415857 AA866115 Hε 127797 Homo sapiens cDNA FLJ 11381 fis, clone HE 858
428847 AI954833 Hs 98881 ESTs 857
408465 AW196940 Hs 253277 ESTs 854
443523 AK001575 Hs 9536 hypothetical protein FLJ 10713 8 53
440527 AV657117 Hs 184164 ESTs, Moderately similar to S65657 alpha 850
439570 T79925 Hs 269165 ESTs, Weakly similar to ALU1.HUMAN ALU S 850
450480 X82125 Hs 25040 zinc finger protein 239 850
425266 J00077 Hs 155421 alpha fetoprotein 850
453884 AA355925 Hs 36232 KIAA0186 gene product 842
413318 AU076607 Hs 75285 inter-alpha (globulin) inhibitor, H2 pol 8 35
430835 AI240006 Hs 192326 ESTs 833
416859 H43437 Hs 80305 hypothetical protein MGC14258 830
423905 AW579960 Hs 135150 lung type I cell membrane-assxiated gly 826
407340 AA810168 Hs 284289 vitiligo-assxiated protein VIT-1 8 25
449260 AA741180 Hs 29879 ESTs 8 25
430255 AK000703 Hs 323822 Homo sapiens mRNA for KIAA1551 protein, 8 18
448844 AI581519 Hε 177164 FGENESH predicted novel cell surface pr 8 17
431840 AA534908 Hs 2860 POU domain, class 5, transcription facto 814
428479 Y00272 Hs 334562 cell division cycle 2, G1 to S and G2 to 8 14
426083 AW962712 Hs 126712 ESTε, Weakly similar to AF191020 1 E2IG5 803
425572 AB011076 Hs 158307 uπdifferentiated embryonic cell transcπ 798
410420 AA224053 Hε 172405 cell division cycle 27 790
453878 AW964440 Hε 19025 DC32 775
430287 AW182459 Hs 125759 ESTs, Weakly similar to LEU5.HUMAN LEUKE 766
453913 AW004683 Hs 78934 mutS (E coli) homolog 2 (colon cancer, 765
421974 AA301270 gb EST14192 Testis tumor Homo sapienε cD 765
432840 AK001403 Hs 279521 hypothetical protein FLJ20530 765
451950 AW292317 Hs 213307 ESTs 760
412265 AA101325 Hs 86154 hypothetical protein FU 12457 759
435514 AW592804 ESTs 755
431041 AA490967 Hs 197955 KIAA0704 protein 755
432415 T16971 Hs 289014 ESTs, Weakly similar to A43932 mucin 2 p 751
418830 BE513731 Hs 88959 hypothetical protein MGC4816 738
409421 AA199883 Hs 67624 ESTs 735
449433 AI672096 Hs 9012 ESTs, Weakly similar to S26650 DNA-bmdi 735
458570 AW971698 Hs 12627 TJ6 protein 730
441287 AW293132 Hs 131373 ESTs 730
434609 R76593 gb yι60c11 r1 Soares placenta Nb2HP Homo 725
432239 X81334 Hs 2936 matnx metalloproteinaεe 13 (collagenase 725
441425 AA933590 Hs 28937 homxbox protein from AL590526 725
446293 AI420213 Hs 149722 LIM domain transcnption fxtor LIM-1 (h 721
414136 AA812434 SMC2 (structural maintenance of chromoso 720
409089 NM 014781 Hs 50421 KIAA0203 gene product 719
422938 NM 001809 Hs 1594 centromere protein A (17kD) 718
441421 AA356792 Hs 334824 hypothetical protein FU 14825 715
452226 AA024898 Hs 157103 ESTs 715
435918 AF263538 Hs 86232 growth differentiation fxtor 3 7 14
418661 NM 001949 Hs 1189 E2F transcnption fxtor 3 710
436360 AI962796 Hs 156100 ESTs 710
442950 AI500417 Hs 46764 ESTs 700
415684 D59356 sorbitol dehydrogenaεe 700
448336 R53848 Hs 44976 ESTε 700
453183 AW086185 Hs 223856 ESTε 700
444434 NM 004849 i Hs 11171 APG5 (autophagy 5, S cereviεiae) like 695
422665 AJ011812 Hs 119018 transcnption factor NRF 695
437421 AA917062 ESTs 695
428916 AF003001 Hs 194562 telomeπc repeat binding factor (NIMA-in 694
408045 AW138959 Hs 245123 ESTs 690
448588 AI970276 Hs 156905 KIAA1676 689
433764 AW753676 Hs 39982 zinc finger protein RINZF (NM.023929) 6 85
439780 AL109688 gb Homo sapiens mRNA full length insert 685 449911 AI262106 Hs 12653 ESTs 685
417791 AW965339 Hs 111471 ESTε 6 80
424085 NM 002914 Hs 139226 replication factor C (activator 1) 2 (40 675
453160 AI263307 H2B hiεtone family, member L 675
453392 U23752 Hs 32964 SRY (sex determining region Y) box 11 675
425427 AI652662 Hs 157205 branched chain aminotransferase 1, cytos 6 73
447254 NM 004153 Hs 17908 origin recognition complex, subunit 1 (y 670
418379 AA218940 Hs 137516 fidgetin like 1 670
407366 AF026942 Hε 17518 gb Homo sapiens cιg33 mRNA, partial sequ 670
414618 AI204600 Hε 96978 hypothetical protein MGC10764 6 69
417153 X57010 Hs 81343 collagen, type II, alpha 1 (primary oste 666
428743 AL080060 Hε 301549 Homo sapiens mRNA, cDNA DKFZp564H172 (fr 665
442717 R88362 Hs 180591 ESTs, Weakly similar to T23976 hypotheti 665
433247 AB040948 Hs 142856 KIAA1515 protein 6 65
430647 AC003682 Hs 127988 ESTs, Weakly similar to Z211 HUMAN ZINC 665
417886 AA214584 ESTs 664
432169 Y00971 Hs 2910 phosphoπbosyl pyrophosphate εynthetase 662
412537 AL031778 nuclear transcnption fxtor Y, alpha 661
426614 AA411925 Hs 301960 ESTε 657
457465 AW301344 Hs 122908 DNA replication factor 652
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 6 50
440801 AA906366 ESTε 6 50
453116 AI276680 Hs 146086 ESTε 650
436909 AA907120 ESTε 650
402199 Target Exon 6 50
419556 U29615 Hs 91093 chitmase 1 (chitotπosidase) 646
421285 NM 000102 Hs 1363 cytochrome P450, subfamily XVII (steroid 641
438494 AA908678 Hs 130183 ESTs 641
418592 X99226 Hs 284153 Fancoπi anemia, complementation group A 640
408758 NM.003686 Hs 47504 exonuclease 1 640
442671 AI005668 Hs 130673 EST 640
432281 AK001239 Hs 274263 hypothetical protein FLJ10377 638
413833 Z15005 Hs 75573 centromere protein E (312kD) 6 35
424081 NM 006413 Hs 139120 πbonuclease P (30kD) 633
441878 AI801869 Hs 127982 ESTs 631
429120 AK001673 Hs 196530 hypothetical protein FU10811 6 31
418221 Z45514 Hs 83775 DiGeorge εyndrome gene D 630
410166 AK001376 Hs 59346 hypothetical protein FLJ10514 630
421650 AA781795 Hs 122587 ESTε 630
453932 AW006303 Hs 329296 ESTε, Weakly similar to (deflme not ava 628
408291 AB023191 Hs 44131 KIAA0974 protein 626
438180 AA808189 Hs 272151 ESTs 625
412026 AA383618 Hs 73073 testis-spxilϊc ankyπn motif containing 625
427510 Z47542 Hs 179312 small nuclear RNA xtivat g complex, po 620
423642 AW452650 Hs 157148 hypothetical protein MGC13204 620
416111 AA033813 Hs 79018 chromatin assembly fxtor 1, subunit A ( 618
407300 AA102616 Hs 120769 gb zn43e07 s1 Stratageπe HeLa cell s393 612
426223 AW977812 Hs 130391 ESTs 6 10
445038 AI635444 Hs 143917 dJ467N11 1 protein 610
419197 N48921 Hs 27441 KIAA1615 protein 609
453775 NM.002916 Hs 35120 replication factor C (xtivator 1) 4 (37 605
436902 AW247145 Hs 192729 ESTs 605
429228 AI553633 ESTε 599
457065 AI476318 Hs 192480 ESTε 590
426572 AB037783 Hs 170623 hypothetical protein FU11183 590
449132 BE045641 Hs 197573 ESTε 590
432359 AA076049 Hs 274415 Homo sapiens cDNA FU10229 fis, clone HE 589
423728 AW891294 Hs 132136 solute earner family 4, εodium bicarbon 5 85
457289 AW573204 Hs 137078 ESTε 585
433849 BE465884 Hs 280728 ESTs 585
412642 BE244598 Hs 809 hepatocyte growth fxtor (hepapoietm A, 585
438450 AI050866 Hs 65853 nodal, mouse, homolog 581
428301 AW628666 Hs 98440 ESTs, Weakly similar to I38022 hypotheti 580
408750 BE294069 Hs 93581 hypothetical protein FU10512 577
415947 U04045 Hs 78934 mutS (E coli) homolog 2 (colon cancer, 577
408460 AA054726 Hs 285574 ESTs 575
442461 AW062564 Hs 285833 Homo sapiens cDNA FU22135 fis, clone H 575
416747 AW876523 Hs 15929 hypothetical protein FLJ 12910 575
428249 AA130914 Hs 183291 zinc finger protein 268 574
419635 NM.005033 Hs 91728 polymyositis/scleroderma autoantigen 1 ( 572
402145 Target Exon 571
447178 AW594641 Hs 192417 ESTε 570
458814 AI498957 Hs 170861 ESTs, Weakly similar to Z195.HUMAN ZINC 565
442980 AA857025 Hs 8878 kinesm like 1 565
419131 AA406293 Hs 109526 ESTs 560
450254 NM 004885 Hs 99231 neuropeptide G protein-coupled rxeptor, 5 60
441627 AA947552 Hs 58086 branched chain aminotransferase 1, cytos 560
440304 BE159984 Hs 125395 ESTs 560
440553 AA889416 Hs 344043 Homo sapiens cDNA FU14459 fis, clone HE 558
442333 AI650877 Hs 129302 ESTs 558
453941 U39817 Hs 36820 Bl∞m syndrome 557
415799 AA653718 Hs 225841 DKFZP434D193 protein 5 57
413623 AA825721 Hε 246973 intron of Bicaudal D homolog 1 5 55 427147 AA398587 Hs 97414 ESTs 5 55
451050 AW937420 ESTs 555
450113 AI683098 Hs 200866 ESTs, Moderately similar to ALU7.HUMAN A 554
418678 NM 001327 Hs 167379 caπcer/testiε antigen (NY-ESO-1) 554
437812 AI582291 Hs 16846 ESTε Weakly similar to 04HUD1 debπsoqu 553
431354 BE046956 Hε 251673 DNA (cytosme 5 ) methyltransferase 3 be 551
449592 AI655494 Hs 195718 ESTs 550
445517 AF208855 Hs 12830 hypothetical protein 550
416658 U03272 Hs 79432 fibπllin 2 (congenital contractural ara 548
430044 AA464510 Hs 152812 ESTs 547
437036 AI571514 Hs 133022 ESTs 547
423006 U29700 Hs 123014 aπti Mulleπan hormone receptor, type II 546
409103 AF251237 Hs 112208 XAGE-1 protein 545
420900 AL045633 Hs 44269 ESTs 545
437257 AI283085 Hs 290931 ESTs, Weakly similar to YFJ7.YEAST HYPOT 545
440738 AI004650 Hs 225674 WD repeat domain 9 545
412723 AA648459 Hs 335951 hypothetical protein AF301222 545
441122 H56777 Hs 121084 eppιn-3 542
414151 AW976468 Hs 257245 ESTs 540
435663 AI023707 Hs 134273 ESTs 540
448986 H42169 Hs 347310 hypothetical protein FLJ14627 539
433701 AW445023 Hε 15155 ESTs 539
443486 NM 003428 Hs 9450 zinc finger protein 84 (HPF2) 535
440842 AA907288 Hs 130173 ESTs 535
432407 AA221036 Hs 13273 gb zr03f12 rl Stratagene NT2 neuronal pr 534
401837 NM 025109 Homo sapienε hypothetical prot 532
423739 AA398155 Hs 97600 ESTε 531
424315 AW614850 Hs 193384 putatative 28 kDa protein 531
453900 AW003582 Hs 226414 ESTε, Weakly similar to ALU8 HUMAN ALU S 530
415717 AA167270 Hs 130435 ESTs 530
428329 AA426091 Hs 98453 ESTs, Moderately similar to R273282 [H 5 26
427119 AW880562 Hs 272525 ESTs 525
432117 AL036195 Hs 2909 protam e 1 524
446837 AW273055 Hs 156598 ESTs 5 23
442007 AA301116 Hs 142838 nucleolar phosphoprotein Nopp34 5 21
422797 AB033064 Hs 236463 KIAA1238 protein 519
446258 AI283476 Hs 263478 ESTs 518
445577 N40696 Hs 137064 cytoplasmic polyadenylation element bind 5 17
445413 AA151342 Hs 12677 CGI-147 protein 517
449670 F07693 Hs 85603 Homo sapienε mRNA, cDNA DKFZp434K2172 (f 516
436211 AK001581 Hs 334828 hypothetical protein FLJ10719, KIAA1794 515
429629 BE501732 Hs 30622 Homo εapienε cDNA FLJ13010 fis, clone NT 515
424235 NM 003181 Hs 143507 T brxhyury (mouse) homolog 515
448038 AW015073 Hs 232026 ESTs, Weakly similar to R052.HUMAN 52 KD 515
430272 X04898 Hs 237658 apolipoprotein A-ll 5 14
422094 AF129535 Hs 272027 F-box only protein 5 513
420424 AB033036 Hs 97594 KIAA1210 protein 513
447924 AI817226 Hs 313413 ESTs, Weakly similar to T23110 hypotheti 510
422631 BE218919 Hs 118793 hypothetical protein FLJ10688 5 10
453448 AL036710 Hs 209527 ESTs 510
438378 AW970529 Hs 86434 hypothetical protein FU21816 506
418235 BE072634 gb PM4-BT0548-171299 001-h08 BT0548 Homo 505
427961 AW293165 Hs 143134 ESTε 505
441553 AA281219 Hε 121296 ESTε 505
429999 AI761902 Hε 99597 ESTs 504
426496 D31765 Hs 170114 KIAA0061 protein 502
410929 H47233 Hs 30643 ESTs 501
448757 AI366784 Hs 48820 TATA box binding protein (TBP)-aεsxιate 501
457107 AA418246 Hs 185796 ESTε, Weakly similar to Z184_HUMAN ZINC 500
408332 H91230 Hs 234794 Homo sapiens mRNA, cDNA DKFZp564B083 (fr 500
440138 AB033023 Hs 318127 hypothetical protein FLJ10201 500
407568 AA740964 Hs 62699 ESTs 500
409798 AA248587 Hs 30237 ESTs, Weakly similar to ALUB_HUMAN "" 500
431215 AA496078 Hs 121554 Human DNA sequence from clone RP11-218C1 500
416350 AF188625 Hs 189507 phospholipaεe A2, group IID 499
452197 AW023595 Hs 232048 ESTs 498
420333 AJ001383 Hs 97084 lymphxyte antigen 94 (mouse) homolog (a 497
403780 C4001759 gι|133250|sp|P19474|RO52_HUMAN 497
418378 AW962081 gb EST374154 MAGE resequences, MAGG Homo 495
418894 W73921 Hs 50743 ESTs 495
426623 AA382826 Hε 132793 ESTs 495
443537 D13305 Hs 203 cholxystokinin B rxeptor 494
414812 X72755 Hs 77367 monokine induced by gamma interferon 494
453716 AA037675 Hs 152675 ESTε 490
402299 Target Exon 490
411945 AL033527 Hs 92137 L-myc-2 protein (MYCL2) 489
414034 U89277 Hs 305985 eariy development regulator 1 (homolog o 487
409066 AA062980 Hs 66960 ESTε 485
437496 AA452378 Hs 146668 Homo εapienε mRNA, cD A DKFZp547J125 (fr 485
416661 AA634543 Hs 79440 IGF-II mRNA binding protein 3 485
450375 AA009647 a disintegnn and metalloprotemase doma 485
416201 AA467752 Hs 195161 ESTs 485
420348 AL137385 Hs 97140 Homo sapiens mRNA, cDNA DKFZp434M1126 (f 484 423198 M81933 Hε 1634 cell division cycle 25A 482
424687 J05070 Hs 151738 matrix metalloprotemase 9 (gelatmase B 481
418971 AA360392 Hs 87113 ESTs 480
411571 AA122393 Hs 70811 hypothetical protein FLJ20516 480
409517 X90780 troponin I, cardiac 480
424322 AL157491 Hs 145211 Homo sapiens mRNA, cDNA DKFZp434K1111 (f 480
443169 AI038687 Hs 133338 ESTs 480
438624 AA889055 Hs 123468 ESTs 479
442562 BE379584 dolichyl-diphosphooligosacchaπde protei 476
412530 AA766268 Hs 266273 hypothetical protein FLJ13346 476
443715 AI583187 Hs 9700 cyclin E1 476
423123 NM 012247 Hs 124027 SELENOPHOSPHATE SYNTHETASE , Human selen 475
451105 AI761324 gb wι60b11 x1 NCI_CGAP_Co16 Homo sapienε 471
444431 AW513324 Hs 42280 Homo sapienε, clone MGC 9010, mRNA comp 471
440591 AA431599 Hs 132799 hypothetical protein FLJ23451 471
424281 AA766243 gb oa13b11 s1 NCI CGAP GCB1 Homo εapiens 470
447175 AI365208 Hs 293606 ESTs 470
408101 AW968504 Hs 123073 CDC2-relaled protein kinaεe 7 469
430183 BE010038 gb PM3-BN0176400400-001-g04 BN0176 Homo 468
416445 AL043004 Hs 79337 KIAA0135 protein 466
429652 AA766810 Hs 259290 ESTs 465
426054 U12431 Hs 166109 ELAV (embryonic lethal, abnormal vision, 465
418618 U66097 Hs 86724 GTP cyclohydrolase 1 (dopa-responsive dy 464
445537 AJ245671 Hs 12844 EGF-like-domam, multiple 6 462
427298 AA400495 ESTs 462
412863 AA121673 Hs 59757 zinc finger protein 281 462
446700 AW206257 Hs 156326 Human DNA sequence from clone RP11-145L2 461
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet-ac 460
446751 AA766998 Hs 79126 Human DNA sequence from clone RP11-16L21 460
432656 NM 000246 Hs 3076 MHC class II transxtivator 460
434283 AW235341 Hs 58715 thiamiπe pyrophosphokmase 460
437915 AI637993 Hs 202312 Homo sapiens clone N11 NTera2D1 teratxa 460
421830 AA789269 Hs 122509 ESTs, Weakly similar to dJ1018D123 [H s 459
440006 AK000517 Hε 6844 NALP2 protein, PYRIN Containing APAF1 Ii 458
450719 AI096837 Hs 21349 ESTs, Weakly similarto RB8B.HUMAN RAS-R 458
431721 AB032996 Hs 268044 KIAA1170 protein 455
423175 W27595 Hs 347310 hypothetical protein FLJ14627 4 55
453529 AA036729 Hs 335639 ESTs 455
416209 AA236776 Hs 79078 MAD2 (mitotic arrest deficient yeast, h 455
444386 BE065183 gb RC1-BT0314-020200-012-C04 BT0314 Homo 455
428976 AL037824 Hs 194695 ras homolog gene family, member I 455
449510 AI653154 Hs 328147 ESTs 455
414725 AA769791 nng finger protein 21, iπterferon-respo 454
424153 AA451737 Hs 141496 MAGE-lιke 2 453
414466 AA349211 Hs 76205 cytxhrome P450, subfamily XIA (choleste 452
448966 AW372914 Hs 86149 phosphomositol 3-phosphate binding prot 450
458443 AV647010 Hs 27 glycine dehydrogenaεe (dxarboxylatmg, 448
453289 AI188161 Hs 144627 ESTε 448
433641 AF080229 gb Human endogenouε retroviruε K clone 1 445
440196 N72847 Hs 125221 ESTε 445
452338 AW608920 Hs 29159 zinc finger protein 75 (D8C6) 445
428855 AI435901 Hs 89563 nuclear cap binding protein εubunit 1 , 8 445
416734 H81213 Hs 14825 ESTε, Weakly similar to KIAA1503 protein 445
442240 AI791883 Hs 292719 ESTε 445
421917 AB028943 Hs 109445 KIAA1020 protein 445
420949 AA934063 Hs 13836 ESTε, Weakly similar to I38022 hypotheti 444
449676 AW380579 Hs 209657 ESTε 443
433183 AF231338 Hs 222024 transcnption factor BMAL2 440
439314 AA382413 Hs 178144 ESTs 440
425312 AA354940 Hs 145958 ESTs 439
427584 BE410293 Hs 179718 v-myb avian myeloblastosis viral oncogen 439
430444 AW296421 Hs 121035 ESTs 435
416773 AK000340 Hs 79828 hypothetical protein FU20333 435
421010 AW974553 Hs 267124 ESTs, Weakly similar to ALU6_HUMAN ALU S 434
418216 AA662240 Hs 283099 AF15q14 protein 432
450351 BE547267 Hs 59791 hypothetical protein MGC13183 432
454073 AW206286 Hs 116727 ESTs 430
417006 AW673606 Hs 80758 aspartyl-tRNA synthetase 430
417576 AA339449 Hs 82285 phosphoπboεylglycinamide formyltransfer 430
448877 AI583696 Hs 253313 ESTs 428
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 427
411630 U42349 Hs 71119 Putative prostate cancer tumor suppresso 425
430292 AK000634 Hs 238270 hypothetical protein FLJ20627 425
427778 AA412323 Hs 105323 ESTs 425
418768 T39310 gb ya04a09 r2 Stratagene lung (937210) H 425
409268 AA625304 ESTs 425
442010 AI032680 Hs 132213 ESTs 424
452807 AA028933 Hs 162434 ESTε 4 23
401435 C14000397* gι|7499898|pιr||T33295 hypoth 423
447519 U46258 Hs 339665 ESTε 421
421307 BE539976 Hs 103305 Homo εapienε mRNA, cDNA DKFZp434B0425 (f 421
424590 AW966399 Hs 46821 hypothetical protein FU20086 420
453909 AW004045 Hs 203365 ESTs 420 431126 AF085243 Hs 283619 zinc finger protein 236 420
429628 H09604 Hs 13268 ESTs 4 20
415989 AI267700 ESTε 420
421373 AA808229 Hs 46677 ESTs 4 20
433979 AA620999 gb ag03a08 s1 Soares_testιs_NHT Homo sap 420
408321 AW405882 Hs 44205 cortistatin 4 19
410193 AJ132592 Hs 59757 zinc finger protein 281 417
430335 D80007 Hs 239499 KIAA0185 protein 417
408031 AA081395 Hs 42173 Homo sapienε cDNA FLJ10366 fis, clone NT 4 16
438885 AI886558 Hs 184987 ESTs 415
451578 NM 016323 Hs 26663 cyclin-E binding prote 1 415
432446 AA542845 Hs 294088 GAJ protein 413
445076 AI206888 Hs 154131 ESTs 411
420218 AW958037 πbosomal protein L4 410
453628 AW243307 Hs 83937 hypothetical protein 410
418459 R85436 Hs 268814 ESTs 410
418866 T65754 gb yd 1c07 s1 Stratagene lung (937210) H 408
440404 AI015881 Hs 324527 mitochondnal πboεo al protem S5 406
426300 U15979 Hs 169228 delta-like homolog (Drosophila) 406
446223 BE300091 Hs 119699 hypothetical protein FU 12969 405
429984 AL050102 Hs 227209 hypothetical protein FLJ21617 405
449687 W68520 intermediate filament protein εyncoilm 405
452109 AI525873 Hs 61164 hypothetical protein FU14909 405
401464 histone deacetylase 5 405
444670 H58373 Hs 332938 hypothetical protein MGC5370 405
415884 H22966 Hs 13471 ESTε 405
442066 BE502147 Hs 128418 ESTε 404
402098 ENSP00000217725* Laminin alpha-1 chain p 402
404287 FGENESH predicted novel CUB domain conta 401
422756 AA441787 Hs 119689 glycoprotein hormones, alpha polypeptide 401
449704 AK000733 Hs 23900 GTPase xtivatmg protein 400
445685 AW779829 gb hπ88a05 x1 NCI CGAP Kιd11 Homo sapien 400
444379 N99035 Hs 30352 ESTs 400
435373 AW665538 Hs 117689 ESTs 400
424557 AA343057 Hs 164588 ESTs, Moderately similar to neuronal thr 400
413646 BE155042 gb PMO HT0349-101299 002-E04 HT0349 Homo 400
418648 AW979223 Hs 292478 ESTs 400
446074 AA079799 Hs 343103 hypothetical protein FLJ11896 400
447353 AI375701 Hs 25884 ESTs 400
410100 AA081636 Hs 271916 ESTs, Weakly similar to S41044 chromosom 400
428856 AA436735 Hs 183171 hypothetical protein FU22002 400
445140 AI650599 Hs 197913 ESTs, Weakly similar to SCP3 MOUSE SYNAP 400
406367 NM.022357 Homo sapiens putative metallop 399
437834 AA769294 gb nz36g03 ε1 NCI CGAP.GCB1 Homo εapiens 399
453985 N44545 Hs 251865 ESTs 3 98
408446 AW450669 Hs 45068 hypothetical protein DKFZp434H43 397
408562 AI436323 Hs 31141 roundabout (axon guidance rxeptor, Dros 397
414713 BE465243 Hs 12664 ESTε 396
426067 AW664691 Hs 97053 ESTε 396
456497 AW967956 Hs 123648 ESTε, Weakly similarto AF1084601 ubinu 396
454679 AW813110 gb CM4-ST0189-051099-021405 ST0189 Homo 395
451865 H43737 Hε 33186 ESTs, Weakly similarto unknown protein 3 95
403137 NM.005381* Homo sapiens nucleolin (NCL), 395
445730 AI624342 Hs 179082 ESTs 3 95
451993 AA765776 Hs 122983 ESTs 395
428819 AL135623 Hs 193914 KIAA0575 gene product 3 92
433683 AI817723 Hs 22678 hypothetical protein FLJ21832 391
420812 AA715303 Hs 107369 ESTs 390
423806 AA331247 Hs 86617 ESTs 390
437205 AL110232 Hs 279243 Homo sapiens mRNA cDNA DKFZp564D2071 (f 390
449211 AI922972 Hs 196073 ESTs 390
409757 NM.001898 Hs 123114 cystatm SN 390
436027 AI864053 Hs 39972 ESTs, Weakly similarto I38588 reverse t 389
432512 NM 003284 Hs 3017 transition protein 1 (dunng histone to 3 89
440840 AW629666 ESTε, Weakly similarto S64054 hypotheti 388
449099 AI629041 Hs 46908 ESTs 3 88
408092 NM 007057 Hs 42650 ZWIO interxlor 385
423909 AJ223183 Hs 135194 immunoglobulin superfamily, member 6 385
437162 AW005505 Hs 5464 thyroid hormone rxeptor coxbvating pr 384
424381 AA285249 Hs 146329 protein kinaεe Chk2(CHEK2) 383
433023 AW864793 thromboεpoπdm 1 382
452571 W31518 Hs 34665 ESTs 381
421413 AI826128 Hs 55209 ESTs, Weakly similar to A4936459 protei 380
440953 AI683036 Hs 124135 Homo sapienε cDNA FLJ 13051 fiε, clone NT 380
420697 AA827705 Hs 26605 ESTε 3 80
407275 AI364186 gb qw34h07 x1 NCI_CGAP_Ut4 Homo εapienε 380
422789 AK001113 Hε 120842 hypothetical protein FLJ10251 3 80
411856 H67899 Hs 4190 Homo sapiens cDNA FU23269 fis, clone C 380
449529 AI990559 Hs 232033 ESTε 380
447444 AK000318 Hs 18616 hypothetical protein FU20311 378
444656 AI277924 Hs 145199 ESTε 377
448674 W31178 Hs 154140 ovary-εpxific acidic protein 377
415829 AW450198 Hs 163742 ESTε 376 436188 AK001049 Hs.48712 hypothetical protein FLJ20736 3.75
402178 C19001998*:gi|6453813|ref|NP_008926.2| b 3.75
418179 X51630 Hs.1145 Wil ε tumor 1 3.75
423545 AP000692 Hs.129781 chromoεome 21 open reading frame 5 3.75
429063 AW363845 Hs.322903 ESTs, Weakly similar to A46010 X-linked 3.75
437440 AA846804 ESTs 3.75
427366 AA885108 Hs.223806 TATA box binding protein (TBP)-associate 3.74
438456 AA913381 Hs.20594 ESTε 3.73
418821 AA436002 Hs.183161 ESTs 3.73
417918 AA209205 Hs.163754 hypothetical protein FLJ 12606 3.73
415912 H08859 Hs.206469 ESTs, Weakly similar to ALU6_HUMAN ALU S 3.71
423020 AA383092 Hs.1608 replication protein A3 (14kD) 3.70
409928 AL137163 Hs.57549 hypothetical protein dJ473B4 3.70
414206 AW276887 Hs.46609 ESTs 3.70
427761 AA412205 Hs.140996 ESTs 3.69
428728 NM.016625 Hs.191381 hypothetical protein 3.68
452631 AI188658 Hs.87496 ESTs 3.68
427719 AI393122 Hs.134726 ESTs 3.68
431869 AA521136 Hs.190176 ESTs 3.67
429830 AI537278 Hs.225841 DKFZP434D193 protein 3.67
420297 AI628272 Hs.88323 ESTs, Weakly similar to ALU1.HUMAN ALU S 3.66
421972 M18185 Hs.1454 gastric inhibitory polypeptide 3.66
403433 NM.001622:Homo sapiens alpha-2-HS-glycop 3.65
456030 AA136106 Hs.184852 KIAA1553 protein 3.65
402408 NM_030920*:Homo sapiens hypothetical pro 3.65
452387 AI680772 Hs.306094 trinucleotide repeat containing 12 3.65
416608 R11499 Hs.189716 ESTs 3.65
417553 L09190 trichohyalin 3.65
408065 AW954272 gb:EST366342 MAGE resequences, MAGC Homo 3.65
431077 AI669133 Hs.115660 hypothetical protein FLJ 12810 3.64
452461 N78223 Hs.108106 transcription factor 3.60
437660 W31708 Hs.55304 ESTs 3.60
420552 AK000492 Hs.98806 hypothetical protein 3.60
419926 AW900992 Hs.93796 DKFZP586D2223 protein 3.59
420161 AI683069 Hs.120817 ESTs 3.59
414747 U30872 Hs.77204 centromere protein F (350/400kD, mitosin 3.59
449571 AW016812 Hs.200266 ESTs 3.56
424727 AW590378 Hs.152519 hypothetical protein FU20674 3.55
441820 AA969119 Hs.143502 ESTs, Weakly similar to envelope protein 3.55
423685 BE350494 Hs.49753 uveal autoantigen with coiled coil domai 3.55
427532 AA442152 Hs.104744 hypothetical protein DKFZp434J0617 3.55
437700 AA766060 Hs.301209 myeloid/ly phoid or mixed-lineage leukem 3.55
438176 AW138970 Hs.122113 ESTs 3.55
453062 AW207538 Hs.61603 KIAA1677 3.55
447064 AB002350 Hs.17262 KIAA0352 gene product 3.55
430056 X97548 Hs.228059 KRAB-assxiated protein 1 3.54
418049 AA211467 Homo sapienε, Similar to nuclear l∞aliz 3.54
434288 AW189075 Hs.116265 Iibrillin3 3.54
439176 AI446444 Hs.190394 ESTε, Weakly εimilar to B28096 liπe-1 pr 3.52
421350 AW301608 Hs.278188 ESTε, Moderately similar to I54374 gene 3.52
413943 AW294416 Hs.144687 Homo sapiens cDNA FLJ12981 fis, clone NT 3.52
412123 BE251328 Hs.73291 hypothetical protein FU10881 3.51
430968 AW972830 gb:EST384925 MAGE reεequeπceε, MAGL Homo 3.50
449467 AW205006 Hs.197042 ESTε 3.50
405935 Target Exon 3.50
429782 NM 005754 Hs.220689 Ras-GTPase-xtivating protein SH3-domain 3.50
411027 AF072099 Hs.67846 leukxyte immunoglobulin-like rxeptor, 3.50
412140 AA219691 Hε.73625 RAB6 interxting, kiπeεin-like (rabkineε 3.49
429183 AB014604 Hs.197955 KIAA0704 protein 3.49
428878 AA436884 Hs.48926 ESTε 3.49
418203 X54942 Hs.83758 CDC28 protein kinase 2 3.49
435068 H16262 Hε.31415 ESTs 3.48
442573 H93366 Hs.7567 branched chain aminotransferase 1, cytos 3.48
451065 AW295132 Hs.222231 ESTs, Weakly similar to granule cell mar 3.48
419741 NM.007019 Hs.93002 ubiquitin earner protein E2-C 3.48
406542 C19000728*;gi|12585552|sp|Q9Y2Q1 |Z257_HU 3.47
422406 AF025441 Hs.116206 Opa-interxting protein 5 3.46
402099 ENSP00000217725*iaminiπ alpha-1 chain p 3.45
418826 AK000375 Hs.88820 HDCMC28P protein 3.45
424513 BE385864 Hs.149894 mitochondrial translational initiation f 3.45
427617 D42063 Hs.199179 RAN binding protein 2 3.45
428361 NM.015905 Hs.183858 transcriptional intermediary fxtor 1 3.45
400268 NM 003292:Homo sapiens translxated prom 3.45
443596 AW026048 Hs.134124 ESTε 3.45
442875 BE623003 Hs.23625 Homo εapienε clone TCCCTA00142 mRNA εequ 3.45
416031 T30290 Hs.107515 ESTs, Weakly similar to T00329 hypotheti 3.45
435244 N77221 Hs.187824 ESTs 3.45
423354 AB011130 Hs.127436 calcium channel, voltage-dependent, alph 3.45
453785 AI368236 Hs.283732 ESTs, Moderately similar to ALU1 HUMAN A 3.45
420686 AI950339 Hs.40782 ESTε 3.44
429467 NM 004477 Hs.203772 FSHD region gene 1 3.43
448769 N66037 Hε.38173 ESTε 3.43
423453 AW450737 Hs.128791 CGI-09 protein 3.41 417705 AW134952 Hs 175220 hypothetical protein FLJ14541 341
410252 AW821182 Hs 61418 microfibrillar-aεsociated protein 1 341
404068 Target Exon 340
401644 Target Exon 340
422364 AF067800 Hs 115515 C-type (calcium dependent, carbohydrate- 340
452907 BE256966 Hs 31652 ESTε, Moderately similar to I54374 gene 340
420281 AI623693 Hs 323494 Predicted cation efflux pump 339
452404 AW450675 Hs 212709 ESTs 3 39
452256 AK000933 Hs 28661 Homo sapiens cDNA FLJ10071 fis, clone HE 339
420892 AW975076 Hs 172589 nuclear phosphoprotein similar to S cer 339
440606 AI828751 ESTs, Weakly similar to I38022 hypotheti 338
425474 Z48054 Hs 158084 peroxisome receptor 1 337
429714 BE561801 Hs 2484 T-cell leukemia/lymphoma 1A 337
446214 AK001322 Hs 14347 hypothetical protein FLJ 10460 3 36
434808 AF155108 Hs 256150 Homo sapiens, Similar to RIKEN cDNA 2810 3 36
448789 BE539108 Hs 22051 hypothetical protein MGC15548 336
421633 AF121860 Hs 106260 sorting nexin 10 336
438192 AI859065 Hs 293807 Homo sapienε AFG3L1 lεoform 1 mRNA, part 336
436511 AA721252 Hs 291502 ESTs 335
402680 Target Exon 335
414598 AI094221 Hs 135150 lung type-l cell membrane-assxiated gly 3 35
449477 AI652602 Hs 197043 ESTs 3 35
413686 AI469213 Hs 71404 ESTs 335
401091 dxay accelerating factor for complement 335
418295 AW970043 Hs 238039 hypothetical protein FLJ 11090 335
433220 AI076192 Hs 131933 ESTs 3 34
453200 AA033832 Hs 212433 ESTs 3 33
427239 BE270447 ubiquitin carrier protein 3 33
418355 L42563 Hs 1165 ATPase, H' transporting, nongastπc, alp 333
421535 AB002359 Hs 105478 phosphoπbosylformylglycinamidinesyntha 331
441243 AI767056 Hs 193002 ESTε 330
440716 AW105245 Hs 146509 ESTs 3 30
400587 C10000649' gι|7296574|gb|AAF51857 1| (AE 330
401148 Target Exon 330
411752 AW236047 Hs 126497 ESTs 330
433252 AB040957 Hs 151343 KIAA1524 protein 330
434008 AA740878 Hs 112982 ESTε 330
444665 BE613126 Hs 47783 B aggreεsive lymphoma gene 330
458067 AA393603 Hs 36752 protein kinase anchoππg protein GKAP42 330
410340 AW182833 Hs 112188 hypothetical protein FLJ13149 329
452761 BE244742 Hs 30532 CGI-77 protein 3 29
451418 BE387790 Hs 26369 hypothetical protein FLJ20287 3 29
429323 NM.001649 Hs 2391 apical protein, Xenopus laevis-like 328
432809 AA565509 Hs 131703 ESTs 327
449426 T92251 Hs 198882 ESTs 327
425174 D87450 Hs 154978 KIAA0261 protein 325
435159 AA668879 Hs 116649 ESTs 3 25
446597 AK001334 Hs 15470 putative nng zinc finger protein NY-REN 325
411554 W22895 Hs 112360 prominin (mouse)-lιke 1 325
447555 AI391662 Hs 160963 Homo sapiens, clone MGC 12318, mRNA, com 325
426931 NM.003416 Hs 2076 zinc finger protein 7 (KOX 4, clone HF 1 325
445093 AI207197 ESTs 325
410275 U85658 Hs 61796 transcnption factor AP-2 gamma (xtivat 324
424568 AF005418 Hs 150595 cytxhrome P450, subfamily XXVIA, polype 324
453293 AA382267 Hε 10653 ESTs 324
421654 AW163267 Hε 106469 suppreεεorof arl (S cereviεix) 3-lιke 323
430552 AA176374 Hs 243886 nuclear autoantigenic εperm protein (his 322
411975 AI916058 Hs 144583 ESTs 322
448140 AF146761 Hs 20450 BCM-like membrane protein prxursor 322
403432 NM.001622 Homo sapiens alpha-2-HS-glycop 321
436515 AJ278111 Hs 195292 putative tumor antigen 321
456505 AA504595 ESTs 321
427668 AA298760 Hs 180191 hypothetical protein FLJ 14904 321
452794 AI192444 Hs 25892 ESTs, Weakly similar to I37356 epithelia 320
427314 AB033024 Hs 175475 KIAA1198 protein 3 20
424051 AL110203 Hs 138411 Homo εapienε mRNA, cDNA DKFZp586J1922 (f 320
452028 AK001859 Hs 27595 hypothetical protein FU21142 320
421002 AF116030 Hs 100932 transcription fxtor 17 320
422225 BE245652 Hs 118281 zinc finger protein 266 320
437549 AA759149 Hs 128757 gb ah70e03 s1 Soareε.testis.NHT Homo sap 320
418524 AA300576 Hs 85769 xidic 82 kDa protein mRNA 320
427642 R40761 Hs 9834 ESTs 320
442765 BE567353 Hε 99480 ESTs 3 20
410048 W76467 Hε 343874 proline oxidase homolog 320
412008 NM 001841 Hs 73037 cannabinoid rxeptor 2 (macrophage) 320
423675 AI990509 Hs 131342 small inducible cytokine subfamily A (Cy 3 20
453895 AA039843 Hs 61948 Homo εapieπs, clone MGC 16466, mRNA, com 320
424144 AA454033 Hs 41644 AKAP-assxiated sperm protein 3 19
428612 AA770001 ESTs 319
422805 AA436989 Hs 121017 H2A histone family, member A 319
444371 BE540274 Hs 239 forkhead box M1 3 18
427528 AU077143 Hε 179565 minichromosome maintenance deficient (S 3 17
451684 AF216751 Hε 26813 CDA14 3 17 452031 AA741314 Hs 865 RAP1 A, member ol RAS oncogene family 3 17
451230 BE546208 Hs 26090 hypothetical protein FLJ20272 3 16
416000 R82342 Hs 79856 ESTs, Weakly similarto S65657 alpha 1C- 3 16
444823 BE262989 Hs 12045 putative protein 315
446528 AU076640 Hs 15243 nucleolar protein 1 (120kD) 315
430388 AA356923 Hs 240770 nuclear cap binding protein subunit 2, 2 315
447801 H88923 Hs 270247 Homo εapiens cDNA FU11977 fis, clone HE 315
424188 AW954552 Hs 142634 zinc finger protein 3 15
436941 AA860383 Hs 292791 ESTs 3 15
400592 Target Exon 315
437642 AL079309 gb Homo sapiens mRNA full length insert 315
450405 AI694913 Hs 279637 ESTs 3 15
414161 AA136106 Hs 184852 KIAA1553 protein 3 15
440129 AA865818 ESTε, Weakly similar to S71886 Ste20 life 3 14
438538 AA832203 Hs 291955 ESTs 314
441013 AI125252 Hs 126419 ESTs 314
450431 AW136797 Hs 266041 ESTs 314
423755 AB037735 Hs 132560 hypothetical protein FLJ 10312 313
434769 AA648884 Hs 134278 Homo sapienε cDNA FLJ12676 fis, clone NT 313
449523 NM 000579 Hs 54443 chemokine (C-C motif) receptor 5 312
410704 BE076754 gb CM 1-BT0601-180200-121 -b10 BT0601 Homo 312
412673 AL042957 Hs 31845 ESTs 3 11
420507 AF093408 Hs 98397 A kinase (PRKA) anchor protem 3 311
423419 R55336 Hs 23539 ESTs 3 11
428925 AW242474 Hs 98960 ESTs 311
426108 AA622037 Hs 166468 programmed cell death 5 3 10
439398 AA284267 Hε 221504 ESTs 3 10
449138 AW294215 Hs 195631 ESTs 310
441795 N58115 Hs 21137 AD024 protein 3 10
456053 S57498 Hs 76252 endothelin receptor type A 3 10
403610 C3001199gι|7494834|pιrI|T15308 hypothet 3 10
421281 AI299139 Hs 17517 ESTs 3 10
429274 AI379772 Hs 99206 ESTs 3 10
438243 AI581311 ESTs 3 10
424800 AL035588 Hs 153203 MyoD family inhibitor 309
429469 M64590 Hs 27 glycine dehydrogenase (dxarboxylatmg, 308
416443 N69469 Hs 194225 ESTs 308
421230 AW958439 Hs 105633 ESTs 307
427906 AA864330 Hs 166520 ESTs 307
414706 AW340125 Hε 76989 KIAA0097 gene product 306
441703 AW390054 Hs 192843 leucine zipper protein FKSG14 306
445679 AI343868 Hs 301059 hypothetical protein FLJ 12488 306
434456 AW452621 Hs 116832 ESTs 305
433228 F28212 Hs 14953 KIAA1491 protein 305
419335 AW960146 Hs 284137 hypothetical protein FLJ12888 305
415227 AW821113 Hs 72402 ESTs 305
421184 NM 003616 Hs 102456 survival of motor neuron protein interx 305
438869 AF075009 gb Homo sapiens full length insert cDNA 305
422726 U11690 Hs 1572 faciogenital dysplasia (Aarskog Scott sy 304
429302 AU076674 Hs 198899 eukaryotic translation initiation fxtor 304
416975 NM 004131 Hs 1051 granzyme B (granzyme 2, cytotoxic T-lymp 304
433914 AF108138 Hs 112160 Homo sapiens DNA helicase homolog (PIF1) 304
411365 M76477 Hs 289082 GM2 ganglioside xtivator protein 304
435726 BE535787 Hs 113170 ESTs 303
426386 AA748850 Hs 125830 bladder cancer overexpressed protein 303
420596 NM.002692 Hε 99185 polymerase (DNA dirxted), epsilon 2 302
427953 AA417944 Hs 44331 ESTs 301
433612 AF078164 Hs 61188 Homo sapiens Ku70 binding protein (KUB3) 301
421305 BE397354 Hs 324830 diptheπa toxin reεiεtance protein requi 300
448048 BE281291 Hs 170408 ESTε, Moderately εimilar to A47582 B-cel 300
434776 AA648988 gb ns41f11 s1 NCI CGAP GCB1 Homo sapiens 300
414132 AI801235 Hs 48480 ESTs 300
430491 AL109791 Hs 241559 Homo sapiens mRNA full length insert cDN 300
433493 AA594915 Hs 155087 ESTs 300
452606 N45202 Hs 90012 hypothetical protein FLJ23441 300
453416 NM 003037 Hs 32970 signaling lymphxytic xtivation molxul 300
TABLE 53B
Pkey Unique Eos probeset identifier number CAT number Gene cluster number
Accession Genbank accession numbers
Pkey CAT Number Accession
432666 144 7 AA558585 AA565499 AI360576 AW204069 AA991648 AA864939
423458 30480.1 BC018070 BG702493 AI204212 AA460929 AA993606 BF926635 AA226938 BG190705 BG186496 AW291865 BG183340 BG195301 BG214539
BG215094 BG198867 BG196332 BG208220 BG212418
430676 60836.2 BG433950BE061583T05808 BE144813 AW812038 BE144812 AW812040 AW812041 AU124350 BE061602 BE061604 BF922595 BE061603
AI352469 BE061601 BI062752 AW818206 BF887722
422828 227063 1 BE671981 BE503379 AI655440 AI337054 AI288920 AI242370 AI825182 AA758081 BF855141 BF091068 418477 4172.1 BC022538 AI990847 BF478249 BG217996 BG212702 BG182057 AW589883 BF000085 AA993969 BG479023 BG220014 BG679466 BE907092
AI623855 AA223956 AA223917 AW022983 AW090580 AW573219 BF514491 BF445397 AA884705 AI910424
443068 18695 17 AV752763 AI032142 N30308 N22181 H95390 AW675632 436812 659779.1 AW978773 AW298067 AA810101 AW194180 AA731645 AI690673 427521 513212 1 AW973352 BF222929 AW016853 BF059130 AI651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 AI206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892
436899 10007971 AA764852 AA736937 422689 874209 T AW954733 AA315006 AW856665 440968 518029.1 AI964001 AI634418 AW236545 AI824860 BF223710 AW139686 AI672051 AI655566 AW025712 N36327 BF222876 N34083 AA911045 N40303
AW835451
427486 6841591 BF510715 BE673055 BE464111 AW590620 AI637939 AA404324 AW236441 AI650952 BF056796 AA974433 421974 8641201 AA301270 AA301379 AA301366 435514 1322881 AA683356 AW592804 AI150287 434609 147391 AF147390 R76593 R76594 414136 30243.1 AJ420453 AL526740 AW968449 AA459140 AA843893 AI566516 AW971760 AA430089 AI753216 AA854268 AA743075 AI864957 AA458920
AI566634 AA211796 BG615512 BE169275 BF983253 BF969462 AA766261 AI769894 AA135833 AI831542 N63376 AA214392 AU154486
AW605017 AW450072 AA446459 BE881875 AI061423 AA598549 AW439151 AA426273 Z40087 AA812434 AA135965 H04812
415684 1869518 BF666746 D59356 BG678312 N56640AA166861 437421 9785541 AA917062 AA757369 AW592218 439780 490821 AL109688 R23665 R26578 453160 6028.5 BC009612 NM 003526 BI597616 AV761592 AV760377 AL601008 BI604131 BE645918 BG187760 BG181525 BG2106348G192999 AI263307
AA344186 AW952966 AA033609 AA037562 AA722183 R79452 H70775 BF674991 BE769437 BG007856 AA037483 AW572535 AI143991
AA084581 AA033610 AV742510 AV735788 R08336
417886 10313341 AA210987 D57294 AA214584AA207006 D56572 412537 14066.1 AK025201 AA425472 AI694282 BG057305 AA907787 AI286170 A1684577 AJ420494 AI809865 BF058095 AI478773 AI160445 AL044114
AW665529 AI129239 AW297152 AI268215 AI469807 AI969353 BE552356 N66509 AA736741 AA382555 AW075811 AV759188 BI259364
BF445142 BG232065 AI141758 AI631202 AI167566 AI208445 AA889823 BF982682 N90322 BI090882 BF208005 AW953918 AL044113 AI016793
AA382556 AW235763 AA927051 AI862075 BE886691 BE619282
440801 26359161 AA906366 AA938956 AI910938 436909 5968351 AW102570 AA907150 AA907120 AA737188 AI248890 AW977353 429228 215430.1 BG676155 BM009591 AI479075 AI025794 AI017967 AA448270 BE466812 AA853422 AI392649 BG952034 AA513384 BF840124 BE714620
AW969605 AI553633
451050 11847.4 BM453041 AA760783 BE218582 AI340046 AW166131 BF515854 AI630296 AA461307 A1090881 AW023059 AA155797 AA115486 AL597396
AW889004AW937420AA137082AA013374 BG619478 BG401839
418235 886897.1 BE072634 BE072653 AA830615AA214736 AA331718 418378 1227421 1 AA218925 AW962081 AA354237 450375 165593 BG570706 BG572749 AW606284 H04021 AA151166 AW954405 AA131254 BG056461 W46291 H01532 H04384 H03231 AA852876 H04410
H59605 BE157601 AA113758
409517 4537.1 NM 000363 X54163 M64247 AI265781 AI760600 AI367238 BE140258 AW207185 AI657074 C03333 AI193911 C05024 C03193 AI950215 C05070
C05613 W17389 C05351 AA311399 C04180 C04896 C05502 C05482 C04456 C04543 C04558 C04551 C03114 C03103 AI369979 AI652255
T12391 T12073 W19390 C02994 C02730 C04434 W07136 R57607 C03339
442562 39593.1 AK056685 BG399272 AA187835 BF821903 AV660550 AV660556 AV660502 BG564397 BE379584 BF446961 AI653056 AW973709 AI653173
BG054997 A1266043 BI054879 AI656750 AI492830 AW021142 AI472184 AW170056 AI082443 AI167921 D59940 BI492088 H74180 AW130886
AI348677 AI278577 AA761517 AI698203 AA115535 AI264790 AW205074 AA860452 AA554902 AI000715 D62102 BE544768 AI376090 D59939
AW242249 AA525421 R34211 R34328 BF248064 BF241437 BF572759 BF218832
451105 1145037.1 BI015205 AI761324 AW880937 AW880941 424281 8920551 AA338252AA338213 430183 17316.1 AK055746 AA039909 BE183282 W60721 AA464867 AA398986 T67280 BF995651 AI675065 BG001051 BF764727 BF766707 BF764717 BF764852
BF173139 BE010038
427298 1152411 AA933717 BF061897 AW628327 AA641788 AA400495 444386 14902371 BE065183 AI144398 BE065367 BF377924 414725 19377.1 NM 058166 AF220030 AL043894 AW974257 AA625445 AU153502 AI650537 AW612116 AI672377 AW772451 BE892241 BE501740 AA718936
AI650276 AI654206 BE503226 AI651327 AW873562 AW271269 AW271565 AI873518 AI207150 AI338826 AI650258 AI628362 AA227117 AI207149
AW052076 AI470776 AA588100 AW235852 AA769791 AI701653 AK027664 AI984770 AU153469 BE222316 AA609539 BE220093 AA609112
BI054316
433641 35983.1 AF080229 AF080232 U87593 U87592 U87591 U87590 AI636743 AI633818 AW206802 AI583718 AF080231 AF080234 AF080233 AL535594
A1818326 AF080230 S46404 AI970376 AA463992 AW665466 BF512210 U87595 U87589 BE550633 AI672574 BE467547 AI680833 AW614951
N29986 N25695 H69001 U87596 BE673974 AI797496 AI701526 AA703396 AW139734 H92278 N66048 BE219539 BE671665 AI624817 BE466611
AI206344 AA574397 BF593413 BG231271 BF773517 U87594 BF062180 BE466420 AI887798 BF674385 AA204735 AW496808 AA204833
AA207155 BI004756 AA206262 AI365204 H77608 AW590511
418768 2293204.1 T39328 T39310 T39303 T39284 409268 109625 1 BE893356 AA625304 AI765607 AI624898 R76060 AA069651 BG998885 R35783 BF086499 AA428755 AI245055 415989 10194.1 BC013389 BC017398 AI023543 AA191424 AI267700 AI469633 AW958465 AW953397 AA172056 BE940298 BF909208 BF909980 BF095153
BG285837 AI720344 BF541715 AA355086 AA172236
433979 2076469 1 N50454 AA620999 T16375 420218 191547.1 AW958037 R42557 AI337047 AA948360 AI638005 AA459950 AI624915 AI638047 AI467856 AI521826 AA860305 AI932315 AW003092 AW271756
AW779380 AA609879 AI634791 A1493770 AI565211 Z41145 AI627952 AA303734 BE349457 AW196765 AA256527 BE089727
418866 245947.1 T65754 AA229658 AA229857 449687 25369 2 AK056550 AK056356 AI928212 AI742073 AW300558 BG058755 AA058343 AI554842 AW207438 BF509981 BF444954 AW026234 AI620104
AA973460 AI370934 N63066 AA493129 AW590888 AI682952 AI167202 AA631394 AI421915 AI222883 BF477519 AI208777 AA765849 AI675076
AI370922 AI339579 AA486224 AA453524 AW771805 AI492842 H54679 AA961022 AW023555 H06192 AA910222 AI660021 AI032525 AI375480
AI361860 AI032919 AA833599 BG057928 AA553913 AW235737 AA002124 AA913636 F04607 AI867699 AA648100 BE091446 AA486378
BE002022 H84627 BI059837 BF917659 BF917100 BF917043 BF917104 BF916878 BG290981 AW954251 AA757126 H11545 AA353384 N48448
AA379845 AA004943 AA379928 AA002123 BM470118 AL598847 AL598830 BG899239 R57470 BF939179 AI650642 AI758851 BF352505 W68422
W35297 H11435 AA937499 AI783996 R12500 AI819557 N39093 Z41619 H22849 AA004942 R09436 R02403T90942 T85823
445685 3816781 BG029683 AI248120 BI850480 AW779829 N22494 413646 15256561 BE155042 BE155040 BE154987 BE155012 437834 294580.1 BG110129 AW749287 BE535498 AW749299 AW749293 AW749302 AW749298 AW749291 AW749294 AW749289 AW749288 AW749296
AA769294 AW749297 AW749295 AW749292 BE002573
454679 1743251 AW813110 BF771370 BF771371 AW813113 AW003381 440840 29686.Ϊ BI862319 AA204955 BF240507 BG212143 A 205739 BI760647 BM129481 BI760482 AW300025 AI288591 AW236114 A1302852 AI038548
AI797207 AA534496 BG188194 AA921877 BG191846 BG182959 BE620243 BF217428 BC009514 BM463015 AL529077 BM051874 BG773269
BM314351 BM314660 A 629666 AA316207AI623431 AA504153 AA314700 BG195449 BG614101
433023 3970_8 BE999967 BF438599 AW864793 AI802899 BE815132 AW468888 AI672189 AI052004 BF112024 AA772335 AW275054 AA573845 AI144148
AI968683 AA846676 AA927355 H80424 AW973295 R88209 F29868 BE928871
437440 2497201.1 AA846804 AA757581 AI050950 AI092024 AA838807 417553 258857.1 AL545411 AI096369 BF431750 AI130946 W60065 W80663 AA258580 W73279 W76156 W80662 AW058658 AI204699 W60115 N56751 N30878
AI769345 R71250 AI363766 R22777 R17009 R27985 R28243
408065 101881.1 BI603077 AW954272 BI598724 AI003154 AA059300 AA046911 BI669907 BI600966 BI669987 418049 12052.4 AJ314647 NM.052888 BI494693 AA835065 AI634477 AI336678 AI807696 BF477887 AI701147 Z39187 R38979 F02234 AA984711 BI222234
AV731417 R42406 H04996 T98498 R12489 R12577 R42405
430968 1237115 1 AW972830 AA489820 AA527647 AA570362 400268 840.4 U69668 AA448366 X63105 BC016514 BE694436 AI655840 AW235355 BG427984 AA612862 AA448223 BM145813 BM194565 AI870824 BE973573
BM148408 AA448232 AA454176 AA740959 AA884391 AA808545 AW070759 BM144223 N75518 BE542983 BE241942 AI124022 AA761687
BF908518 BF907890 R11490 AL536642 BF109180 AA953881 AI783716 BE622908 AI621005 AW148784 AI690114 AW275000 AI765790 BF222859 0 AW167268 AI990460 AW300443 AA779660 AI620568 BF115024 BE504703 AW628332 A1922851 BE006636 AU158376 AI168279 AA809916
AI469757 AA830828 AA830388 N64324 AI049683 AA970275 BF477364 BG261301 AA326388 AU150565 AU158374 AA687967 N58510 AI650450
AL549572 BF349280 BF349269 BM463016 AW836798 AL120958 AW836891 AW385525 BE175733 BE175727 BE175723 BF092430 BI061782
AU135358 BE175731 BE175754 BE175756 BE841747 BF798384 AU128251 BF095246 BG223262 AW847833 AL536643 AW366516 AW391532
BE934857 BF925057 AW438446 R86246 AW179270 BE087782 BI832144 5 440606 10075.1 BC017350 BC021031 AI220219 AI828751 AW134498 BE139642 AA894554 AI278594 AV747315 BE561749 BI085890 T80117 H69682 N70904
AV741999 H70098 427239 20459 2 AL532360 BE794750 AA582906 AI015067 AW271034 BG271636 AW075177 AW071374 AI345565 AI307208 BE138953 BE049086 AI334881
AW075006 AW075181 AA464019 AW302733 AW075100 AW073433 AI802854 AI334909 AI802853 AI345036 AI348921 AI340734 AI307478
AI251289 AW302327 AW072520 AI312145 AW073656 AW072513 AW071289 AI307559 AA876186 T29587 AI307493 AI255068 AI252868 AI252839 0 AW074809 AI252926 AI252160 AI251662 AI251262 AI610913 AI270787 AI270156 AI252075 AW073469 AW072901 AW072496 AW071420
AI305762 AI254764 AI802837 AI251264 A 073049 AW071311 AI340643 BE138965 BE138502 AW073456 AI334733 AΪ054335 BE139260
AI054302 AI054060 AI054057 AI053722 AI289711 BE139228 AW470478 AW271039 AW302085 BE041872 AI254494 AI271496 AI252427
BF718773 BF718645AW074866BE857822
445093 175963.1 AI207197 BF773544 AW196462 5 456505 15472.2 BC017965 AW969075 AA279982 AA504511 AI219979 AA504595 AI245579 AA278181 BG485019 BI049312 428612 1383189.1 AA770001 AA431112AA432126 437642 77594.1 AL079309AA281819 440129 2607882.1 AI732997 AA977633 AA865818 410704 1054673 1 AW877458 AW877524 BE076922 BE166912 AW840534 BE076754 AW797829 BE166905 BE166926 AW877462 BE166927 BE166932 AW877523 0 BE166917 AW877529 BE166928 BF351394 AW877522 AW877528 BE166861 BE166866 BE166913 BE166919 AW877456 AW877537 BE076866
AW840571
438243 2532601 1 AI581311 AA781682AA781678 438869 52134.1 AF075009 R63109 R63068 434776 118129 1 AW974599AA648988 R98760 5
TABLE 53C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numberε in thiε column are Genbank Identifier (Gl) numbers "Dunham, et al " referε to the publication entitled "The DNA sequence of 0 human chromosome 22" Dunham, et al (1999) Nature 402489-495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLpoεition 5 406547 7711513 Minus 172780-174358
404996 6007890 Pluε 37999-38145,38652-38998,39727-39872,4055
402199 8576116 Minus 84187-84744
402145 8018280 Plus 113086-114800
401837 7630990 Minus 120993-121095,121660-121729 0 403780 8076989 Plus 93160-93409
402299 6693370 Pluε 23367-25175
401435 8217934 Minus 54508-55233
401464 6682291 Minus 170688-170834
402098 8117697 Minus 44186-44330 5 404287 2326514 Plus 53134-53281
406367 9256126 Minus 58313-58489
403137 9211494 Minus 92349-92572,92958-93084,93579-93712,9394
402178 8575912 Pluε 391138-391711
403433 9719611 Minus 72225-72437 0 402408 9796239 Minus 110326-110491
405935 6758795 Minus 163112-163652
406542 7711499 Plus 117335-118473
402099 8117697 Pius 121553-121742,123265-123423
404068 3168621 Minus 18123-18766 5 401644 8576138 Plus 82655-83959
402680 8113438 Plus 137634-137768,139702-139893,140475-14059
401091 9958240 Plus 94760-94898
400587 9887626 Plus 25435-25588,25668-25747
401148 2547238 Minus 22521-23053 0 403432 9719611 Minus 68204-68392
400592 9887642 Minus 24642-24815
403610 8308266 Pluε 157705-157860
TABLE 54A
75 Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
_ . R1 Ratio of normal testi to normal adult tisεueε U R2 Ratio of "average" normal testi to "average" testicular cancer
Pkey ExAccn UnigenelD Unigene Title R1 R2 401979 C17000767 gι|11990770|emb|CAC19651 1| (A 1008 433
421825 AA298758 Hs 183747 ESTs, Moderately similar to CALB.HUMAN C 1035 368
408493 BE206854 Hs 46039 phosphoglycerate mutase 2 (muscle) 574 320
441728 AI797395 Hs 169797 Homo sapiens BOULE (BOULE) mRNA complet 1054 245
452215 AK002043 Hs 28472 hypothetical protein FLJ 11181 486 220
415211 R64730 Hs 155986 DEAD/H (Asp Glu Ala Asp/His) box polypep 693 198
418677 S83308 Hs 87224 SRY (sex determining region Y) box 5 494 185
449108 AI140683 Hs 98328 hypothetical protein MGC13040 7 94 17 5
420437 AA992768 Hs 97633 A kinase (PRKA) anchor protein 4 1675 15 6
436632 AA724299 Hs 304020 ESTs, Weakly similarto CRTC.HUMAN CALRE 651 149
418409 AA219332 Hs 120869 ESTs, Weakly similar to R107.HUMAN H REV 496 146
406409 Target Exon 398 143
427060 AW378993 Hs 90286 ESTs 3 56 142
427310 AI613480 Hs 47152 tektin 3 450 140
427166 AA431576 Hs 99154 ESTs 428 13 9
427178 AA398866 Hs 97542 Homo sapiens testiε development related 10 19 137
410694 AL137538 Hs 65500 Homo εapienε mRNA, cDNA DKFZp434N2019 (f 576 134
424310 AA338648 Hs 50334 teεteε development-related NYD-SP22 5 24 133
427441 AA412605 Hs 343879 SPANX family, member C 1045 126
438057 AW294544 Hs 125785 ESTs, Weakly similar to CORB MOUSE CORNI 1857 123
422183 AA431698 Hs 112794 Human DNA sequence from clone 1068E13 on 5 18 12 3
427293 AA705799 Hs 183714 ESTs 1079 121
444963 AI916973 Hs 213603 ESTs 3 18 121
428608 AI699329 Hs 99168 ESTs, Weakly similar to AF1329721 CGI-3 1540 11 8
453178 AA496086 Hs 61648 ESTs 413 11 8
428618 AA885360 Target CAT 753 11 5
401741 Target Exon 1041 11 5
422086 AW182930 Hs 250182 ESTs 439 107
426604 H53354 Hs 97141 ESTs, Weakly similar to hypothetical pro 704 106
442373 AI377758 Hs 164799 testes development related NYD-SP17 823 103
427455 AF173081 Hs 178215 Vertebrate LIN7 homolog 1 , Tax interxti 303 10 1
437248 AW449340 Hs 93090 ESTs 906 101
426608 AA444162 Hs 99344 hypothetical protein PRTD-NY3 3 68 100
427297 AW292593 Hs 334907 Homo sapiens, clone MGC 17333, mRNA, com 970 98
422358 AL133030 Hs 115429 Homo sapienε mRNA for KIAA1666 protein, 11 85 97
451610 AW118604 Hs 207126 ESTε 563 97
410630 BE044562 Hs 266847 ESTε, Weakly similar to KIAA1214 protein 438 95
426677 AW949856 Hs 97165 ESTs 658 93
437558 AI126471 Hs 124112 ESTs, Moderately similar to HSJ2.HUMAN D 447 92
423088 NM 006687 Hε 123530 xtin like 7A 1507 89
426476 NM.003296 Hs 2042 testis specific protein 1 (probe H4-1 p3 18 55 89
421952 AA300900 Hs 98849 dynein light chain 2B (DNLC2B) 1393 88
429877 W37337 Hs 103014 ESTs 697 87
413114 AI825838 Hs 75206 protein phosphatase 3 (formerly 28), cat 378 86
412026 AA383618 Hs 73073 testis spxific ankyππ motif containing 2203 85
411844 AI807681 Hs 144658 ESTs, Weakly similar to T17257 hypotheti 7 34 83
436868 AA974253 Hs 120319 Homo sapienε autoimmune infertility rela 416 82
426599 AW183574 ESTε 629 81
426683 AI073430 Hs 146775 ESTε, Weakly similar to T30993 hypotheti 1089 80
426930 AA393442 ESTs 506 80
427836 AA416642 Hs 116176 ESTs 479 80
407721 Y12735 Hs 38018 dual-spxιficιty tyroειne-(Y)-phosphoryl 511 79
430822 AJ005371 Hs 248017 glyceraldehyde-3-phosphate dehydrogenase 21 26 76
434150 BE047007 Hs 116116 testis spxific, 10 485 76
422789 AK001113 Hs 120842 hypothetical protein FLJ10251 1029 75
422116 H64205 Hs 111850 mitxhondπal capsule selenoproteiπ 912 75
433724 AI827749 Hs 144924 seππe/threonine protein kmase SSTK 2224 74
410187 AA860341 Hs 104680 ESTs 303 74
419584 AF053356 Hs 283764 F-box only protein 24 643 74
458182 AI147996 Hs 155833 ESTs, Weakly similar to εplicxsomal pro 990 73
418665 T19204 Hs 195685 ESTs 714 73
426646 AA382787 Hs 122713 ESTs 703 73
420349 NM.016611 Hs 97174 potassium iπwardly-rxtifying channel, s 1490 73
428624 AI125222 Hs 98712 hypothetical protein DKFZp434H0311 371 71
420710 NM_007009 Hs 99875 zona pellucida binding protein 2078 71
434317 AI674095 ESTε 398 7 1
443432 AI056863 Hs 339871 ESTs 346 70
425709 AA383076 Hs 159274 outerdensefibre ofεperm tails l 2321 70
426670 AA383047 Hs 310210 ESTs 692 70
408613 AW242086 Hs 253967 ESTs 577 68
452235 AL039743 Hs 28514 teεteε development-related NYD-SP21 923 67
434133 AI655275 Hs 236635 ESTε, Weakly similar to ATHUB xtin beta 746 67
427294 AA412594 Hs 125902 ESTs 344 67
427262 AA448509 Hs 128652 ESTε 566 65
429851 AA459835 Hs 120573 hypothetical protein DKFZp434K1172 9 01 65
406378 NM 021247* Homo εapiens protamme 3 (PRM 396 64
425865 AA393491 Hs 183740 ESTs 9 15 64
428665 NM 017481 Hs 189184 ubiquitin 3 11 07 64
439379 AA835002 Hs 125611 ESTs 506 63
427520 BE467881 Hs 97489 ESTs, Weakly similarto B28096 lιne-1 pr 9 29 62
458940 BE149824 Hs 132888 KIAA1674 311 62
426620 AW450252 ESTs 1227 62
429516 AI653299 Hs 99354 ESTε, Weakly similar to hyperpolanzatio 9 15 61 426736 AA431615 Hε 130722 ESTs 358 61
427843 AC005622 Hε 180943 hypothetical protein R30953 1 634 6 1
426639 AI799059 Hε 112807 ESTs 693 60
438637 BE500941 Hs 126730 ESTε, Weakly similar to KIAA1214 protein 304 60
433795 AI216683 Hs 122599 ESTs, Weakly similar to ALU7.HUMAN ALU S 1045 59
441232 AI656050 Hs 7086 hypothetical protein MGC12435 427 59
433943 AA992805 Hs 44865 lymphoid enhancer-binding factor 1 687 58
426955 AA393669 Hs 238094 ESTs 475 58
428918 AL036967 Hs 2324 prota ine 2 3840 58
427851 AA846543 Hs 98257 ESTs 15 87 58
428208 AA442327 Hs 104854 ESTs 634 57
422207 AI828862 Hs 10964 ESTs 6 43 57
431153 AW972342 Hs 77823 hypothetical protein FLJ21343 924 57
419350 AC005328 Homo sapiens chromosome 19 cosmid R2666 14 94 56
427107 AA889586 Hs 180346 ESTs 625 56
429461 AI188219 Hs 99311 ESTs, Weakly similarto HSJ2_HUMAN DNAJ 3 92 56
432512 NM 003284 Hs 3017 transition protein 1 (duππg histone to 2203 56
434451 AW445179 Hs 121438 ESTs 7 89 55
420348 AL137385 Hs 97140 Homo sapiens mRNA, cDNA DKFZp434M1126 (f 11 26 55
427214 AA442240 Hs 178213 ESTs 841 55
458658 AI301117 Hs 122055 ESTs 4 35 55
457034 AA398061 Hs 296587 Homo sapiens chromosome 21 segment HS21C 11 29 54
423120 AW160551 Hs 124021 soggy-1 gene 8 88 54
438983 AF085884 Hs 20029 proacrosm binding protein sp32 prxurso 2269 54
426619 AI357194 Hs 119284 ESTs 7 07 54
440822 A1554897 Homo sapiens clone 191B7 plxenta expres 3 60 54
416205 AA176396 Hs 169624 ESTs 10 26 54
426712 AW173177 Hs 197755 hypothetical protein MGC5356 817 53
427840 AI216654 Hε 98251 ESTε 644 53
439314 AA382413 Hs 178144 ESTs 835 53
426943 BE551631 Hs 20969 ESTs 6 31 52
409209 AA460160 Hs 73217 ESTs 785 52
441710 AI187883 Hs 127510 ESTs Weakly similar to ENC1.HUMAN ECTOD 773 5 1
420571 AA442366 Hs 98952 Human DNA sequence from clone RP1-39G22 939 51
428563 AA431616 Hs 98660 ESTs 14 94 5 1
433994 AL042483 Hs 335499 ESTs 684 50
441856 AI674774 Hs 128014 ESTs 3 74 50
427789 AA412428 Hs 48642 hypothetical protein FLJ23093 429 50
418967 NM.001725 Hε 89535 bacteπcidal/permeability-increasmg pro 4 14 49
430232 AA469940 Hε 105324 ESTs, Moderately similar to FRHUH ferπt 1066 49
421850 AW274576 Hε 121021 ESTs 12 27 49
449436 AA860329 Hs 279307 hypothetical protein DKFZp434l2117 450 49
426699 AA383337 Hs 121269 ESTs 5 67 49
426627 AF012359 Hs 195685 ESTs 2066 49
427285 AA401664 Hs 97784 ESTs 472 48
423693 AL133633 Hs 131779 Homo sapienε mRNA, cDNA DKFZp434E2118 (f 603 48
457019 AA421844 Hs 12830 hypothetical protein 387 48
405264 NM 030813* Homo εapieπε εuppreεεor of po 448 48
450606 AI668605 Hs 60380 ESTε, Moderately similar to ALU6_HUMAN A 376 48
421378 L77564 Hs 103978 seπne/threonme kinase 22B (spermiogene 735 48
431215 AA496078 Hs 121554 Human DNA εequence from clone RP11-218C1 866 47
427423 BE267041 Hs 177926 exonucleaεe NEF-εp 19 27 47
438756 AW081754 Hs 303923 hypothetical protein DKFZp434L1717 1205 47
424197 AF096834 Hs 142989 germ cell spxific Y-box binding protein 1770 47
423284 AC005764 Hs 126496 Homo sapienε chromosome 19, cosmid R3134 7 50 47
432117 AL036195 Hs 2909 protamine 1 55 33 47
424426 AI476416 Hs 132888 KIAA1674 541 46
437387 AI198874 Hs 28847 AD026 protein 504 46
420718 NM.002301 Hs 99881 Ixtate dehydrogenase C 918 46
420768 AI468780 Hs 292503 ESTs, Weakly similar to T47142 hypotheti 570 46
423677 M86808 Hs 131361 pyruvate dehydrogenase (lipoamide) alpha 1093 45
436661 AI125270 Hs 128069 ESTs, Weakly similarto T19142 hypotheti 3 82 45
427749 BE045979 Hs 98095 Homo sapienε cDNA FLJ23052 fiε, clone L 645 45
441830 AA383104 Hs 42954 hypothetical protein DKFZp564D0372 11 29 45
427877 AW138725 Hs 178067 ESTs 409 45
426623 AA382826 Hs 132793 ESTs 26 62 45
429965 AL040379 Hs 99551 Homo sapiens cDNA FLJ11789 fis, clone HE 1325 45
451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 388 44
417592 AA204664 Hs 182437 ESTε, Weakly similar to I54383 chromosom 346 44
421938 AA405951 gb zu66c01 r1 Soares_testιs_NHT Homo εap 469 44
424144 AA454033 Hs 41644 AKAP-assxiated sperm protein 19 15 44
426710 BE041517 Hs 143893 ESTs 5 57 44
428710 AI890919 Hs 126780 ESTs, Weakly similarto T12519 hypotheti 11 86 44
438641 AW138484 Hs 190653 ESTs 6 19 44
420614 AL110291 Hs 99364 putative transmembrane protem 686 44
422705 NM 006686 Hs 119287 actm like 7B 973 44
421805 AL042716 Hs 130947 hypothetical protein DKFZp434N1415 589 44
448963 AA459796 Hs 331247 Homo sapiens, clone IMAGE 3610712, mRNA, 677 43
426738 AA421097 Hs 291902 ESTs 349 43
440403 AW665135 Hs 130531 ESTs 697 43
456085 AI184560 Hs 130352 ESTs Weakly similar to A47582 B-cell gr 630 43
439594 AI245026 Hs 111099 hypothetical protein MGC10974 785 43
428909 AI190714 Hs 98945 ESTs 779 43 426735 T78716 Hs 120446 ESTs 510 43
438653 AW188099 Hs 131813 ESTs 529 43
443038 AI968058 Hs 209206 ESTs Weakly similar to S38782 actin bet 7 29 42
428677 AI657119 Hs 120036 troponin 1, cardiac 1073 42
424220 AK000869 Hs 143251 hypothetical protein 913 42
426299 H93373 Hs 169222 xrosomal vesicle protein 1 487 42
428871 AA913840 Hs 98903 ESTs 376 42
410163 AF151977 Hs 59260 NTT5 protein 729 42
433133 AB027249 Hs 104741 PDZ-b ding kmase, T cell originated pr 529 42
427757 AI142295 Hs 129794 ESTs 357 4 1
426721 AA383588 Hs 131816 ESTs, Weakly similar to T29012 hypotheti 11 13 41
401692 Cl 6000122" gι|5689527|db]|BAA83047 1| (A 6 37 41
403783 NM 031956 Homo sapiens NYD SP14 protein 374 40
421611 AA459841 Hs 97309 ESfs 11 51 40
404271 ENSP00000244792* Phosphoglycerate kinase 402 40
441800 AW027571 Hs 7973 hypothetical protein DKFZp434G156, KIAA1 886 40
423000 AF049615 Hs 122959 Huntiπgtiπ interacting protein M 360 40
423118 AL035460 Hs 124009 Human DNA sequence from clone RP5 860F19 484 40
420419 AA397796 Hs 11614 HSPC065 protein 407 39
435897 AF269223 Hs 128322 t-complex 11 (a murine top homolog) 23 29 39
428516 R38137 Hs 156469 ESTs, Moderately similar to KIAA0940 pro 528 39
427179 AA400590 Hs 97543 ESTs 618 39
426609 AL040604 Hs 99344 hypothetical protein PRTD NY3 10 07 39
452579 AA131657 Hs 23830 ESTs 524 39
441443 BE465999 Hε 129293 ESTε 460 39
427709 AI631811 Hε 180403 STRIN protein 382 39
435484 AA682756 Hs 88051 ESTs 510 39
425555 AA359291 Hs 130767 Homo sapieπε cDNA FLJ23553 fis, clone L 461 38
436302 AL355841 Hs 99330 hypothetical protein FLJ23588 714 38
421620 AA446183 Hs 91885 ESTs, Weakly similar to 155214 salivary 5 20 38
427086 AA436131 Hs 188781 ESTε 576 38
420475 AW408407 Hs 187018 ESTε 399 38
441357 AI240184 Hs 343487 ESTε 463 38
436643 AA757626 Hs 10941 ESTε, Weakly similar to IPP1_HUMAN PROTE 804 38
441806 AI024442 Hs 346385 ESTs 548 38
413209 AW083791 Hs 21263 suppreεεor of potaεεium transport defxt 902 38
414544 AA149285 Hs 115659 hypothetical protein MGC5521 10 15 38
427251 A1026844 Hs 98843 ESTs, Highly similar to GRA2_HUMAN GLYCI 769 38
437982 N93466 Hs 121764 ESTs, Weakly similar to testicular tekti 346 37
442589 BE409869 protein kinase, cAMP dependent, regulato 450 37
425841 BE262951 Hs 99052 ESTs 826 37
410350 AA446395 Hs 62595 chromosome 9 open reading frame 9 764 37
440487 AI203685 Hs 135763 ESTs 590 37
419455 AW172570 Hs 14600 ESTs 423 37
436588 AA759233 ESTs 504 37
421610 AA393168 Hs 90034 hypothetical protein FLJ21916 553 37
441982 AI216902 Hs 48802 ESTs 479 36
427288 AI139000 Hs 97792 hypothetical protein DKFZp434l099 517 36
414439 W45387 Hs 100007 regulatory factor X, 2 (influences HLA c 443 36
401798 Target Exon 483 36
433395 AF039442 Hs 160881 Homo sapienε colon cancer antigen NY-CO- 3 17 36
438064 AI476330 Hs 234934 ESTs 356 36
426658 AA397912 Hs 115366 Human DNA εequence from clone RP4-803K15 726 36
431986 AA536130 Novel human gene mapping to chomosome 20 6 13 36
427872 AA835058 Hs 9622 Human DNA sequence from clone RP1-261G23 404 36
437896 AA813689 Hs 123436 ESTs, Weakly similar to KIAA1205 protein 469 36
420431 AB007131 Homo sapiens cDNA FLJ12825 fis, clone NT 424 35
409467 Z22780 Hs 307358 cylicin, basic protein of sperm head cyt 513 35
422770 AL117544 Hs 120021 DKFZP434I092 protein 802 35
437399 AI808626 Hs 121188 ESTs, Weakly similar to T29922 hypotheti 503 35
428448 AA625766 Hs 98609 ESTs, Weakly similar to A Cham A Coagu 430 35
426705 AL042749 Hs 97714 ESTs 1045 35
427312 AA400657 Hs 135283 ESTs 447 35
423329 AF054910 Hs 127111 tektin 2 (testicular) 440 35
439290 AI638094 Hs 236896 ESTs 329 34
451481 AA300228 Hs 295866 hypothetical protein DKFZp434N1923 6 18 34
420500 AC005261 Hs 98338 senπe/threonine kinase 13 (aurora/IPLI- 624 34
441168 AI198850 Hs 131654 DMRT-like family B with prolme-πch C-t 10 39 34
420482 X57655 Hs 98243 senne protease inhibitor, Kazal type, 2 2038 34
426988 AI208684 Hs 163960 Homo sapienε heat εhxk tranεcnption fa 502 34
444968 AW628609 Hs 148653 ESTε 5 10 34
429210 AA448011 Hs 131918 ESTs 422 34
442970 R28215 Hs 143878 Homo sapiens mRNA for FLJ00024 protein, 420 34
422782 AL133054 Hs 120369 hypothetical protein DKFZp434H2215 472 34
436601 AA969884 ESTs 484 34
421209 AJ010230 Hs 102576 ret finger protein like 1 antisense 783 34
415705 U06632 Hs 966 coilm 6 30 34
435587 AF215924 Hs 97899 putative allaπtoicase 348 33
427572 AA417291 Hs 97978 hypothetical protein MGC4766 similar to 354 33
427541 AI798983 Hs 82921 solute camerfamily 35 (CMP-εialic aci 1033 33
429404 NM.005738 I Hs 201672 ADP-πbosylation factor-like 4 3 57 33
415014 AW954064 Hs 24951 ESTs 403 33
420547 AF155140 Hs 98738 gonadotropm regulated testicular RNA he 1076 33 412092 H43229 Hs 125201 ESTs, Weakly similar to I38022 hypotheti 5 27 33
441579 AW468847 Hs 127194 ESTs 713 33
420619 AF130255 Hs 99430 testis zinc finger protein 5 19 33
425368 AB014595 Hs 155976 cullm 4B 307 33
425638 NM 012337 Hs 158450 nasopharyngeal epithelium specific prote 3 52 33
429938 BE296804 Hs 226377 phosphate cytidylyltransferase 2, ethano 303 33
453017 R84301 Hs 31387 DKFZP564J0123 protein 330 33
424466 AL040420 Hs 148250 Homo sapienε mRNA, cDNA DKFZp434N1535 (f 481 33
442084 H81173 Hs 34596 ESTs 478 33
423196 AK001866 Hs 125139 hypothetical protein FLJ 11004 463 33
434183 AW104257 Hs 123426 ESTε, Weakly similarto SN1L HUMAN PROBA 573 33
428093 AW594506 Hs 104830 ESTs 695 33
433982 AA724720 Hs 112941 ESTs 511 32
429821 AL096749 Hs 225433 Homo sapiens mRNA, cDNA DKFZp434G153 (fr 404 32
408415 AW418788 ESTs Weakly similarto S43569 R01H106 349 32
407722 BE252241 Hs 38041 pyπdoxal (pyπdoxme, vitamin B6) kinas 677 32
402857 Target Exon 319 32
416667 AK000526 Hs 79457 hypothetical protein FLJ20519 369 32
435114 AA775483 Hs 288936 mitxhondπal πbosomal protein L9 1429 32
427748 AA421041 ESTs 457 32
422794 AJ011733 Hs 120857 synaptogyππ 4 4 23 32
417488 AL046052 Hs 321046 hypothetical protein FLJ 11743 357 32
440115 R41808 ESTs, Weakly similar to B Cham B, Solut 467 32
437143 AW204056 Hs 8917 ESTε 4 16 32
417473 M55268 Hs 82201 casein kinase 2, alpha prime polypeptide 402 32
426594 AA884317 Hs 97130 ESTs 345 32
428733 AA346824 Hs 191996 Homo sapienε organic cation tranεporter 6 29 32
440864 AI382142 Hs 132104 ESTε 848 32
427141 AW628007 Hs 97643 testis spxific protein TSP-NY 560 32
431534 AL137531 Hs 258890 Homo sapienε mRNA cDNA DKFZp434F0919 (f 510 32
438670 AI275803 Hs 123428 ESTε 408 32
412443 AW951103 Hs 130767 Homo εapiens cDNA FLJ23553 fis, clone L 426 32
452251 R37132 Hs 65009 ESTs 401 31
444141 AW629475 Hs 8977 ESTs, Weakly similar to RED1.HUMAN DOUBL 489 31
428254 AK000542 Hs 183362 hypothetical protein FLJ20535 523 31
421621 AL045589 Hs 180197 ESTs 709 31
451017 BE391847 Hs 181173 hypothetical protein MGC10771 357 31
457138 AW140059 Hs 98579 ESTs 13 17 31
428524 AA429772 ESTs 440 31
428726 AA432195 Hs 98694 ESTs 647 31
431310 AW327889 Hs 252433 Homo sapiens cDNA FLJ 13794 fis, clone TH 407 31
428076 AA420979 Hs 234895 ESTs, Weakly similarto Lysozyme [H sapi 597 3 1
427532 AA442152 Hε 104744 hypothetical protein DKFZp434J0617 345 31
424450 AL137526 Hε 147472 dynein intermediate chain 2 601 3 1
433963 AI218808 Hs 187778 ESTs 568 31
424181 AL039482 Hs 142517 Homo εapienε mRNA, cDNA DKFZp434P0810 (f 320 31
440933 AI208217 ESTε 344 31
441854 AA215990 Hs 99841 ESTs, Weakly similar to dJ1108D11 1 [H s 403 3 1
423313 NM 014269 Hs 126838 a disintegnn and metalloprotemase doma 636 31
428630 AA431270 Hs 140646 ESTs 359 31
448813 AF169802 Hs 22142 cytxhrome b5 reductase b5R 2 563 30
434720 AI208541 Hs 189160 ESTs, Weakly similarto cytxhrome c-lik 604 30
436328 AI201145 Hs 122042 Human DNA sequence from clone RP4-576H24 710 30
429293 AI767879 Hs 99214 ESTs 569 30
427255 AA400082 Hs 343593 ESTε, Weakly similar to TD54JHUMAN TUMOR 537 30
440713 AA904448 Hs 126368 ESTs 628 30
418499 AI627392 Hs 302023 hypothetical protein FKSG25 788 30
423218 NM 015896 Hs 167380 BLu protein 668 30
444644 AW070634 Hs 144794 ESTs 500 30
430252 AI638774 Hs 105328 testes development related NYD-SP20 21 75 30
427829 AI188225 ESTs 736 30
426879 AI969340 Hs 115437 hypothetical protein MGC3048 724 30
427362 AA625582 Hs 97752 EST 438 30
441973 T60072 Hs 10688 ESTs, Weakly similar to HRIHFB2157 [H sa 406 29
428989 AF104260 Hs 194712 piwi (Drosophιla)-lιke 1 445 29
438735 M76676 ESTs 381 29
432238 AL133057 Hs 274135 Homo sapienε mRNA, cDNA DKFZp434K1815 (f 11 37 29
427586 AA609661 Hs 190592 ESTε, Moderately similar to WASP-family 626 29
427306 AI476743 Hs 229275 ESTs 300 29
418725 AL117637 Hs 306094 DKFZP434I225 protein 713 29
456748 AW137749 Hs 125902 ubiquitin spxific protease 2 348 29
443162 T49951 Hs 9029 DKFZP434G032 protein 360 29
433836 AA610065 Hs 179646 ESTs 333 29
439680 AW245741 Hs 58461 ESTε, Weakly similar to A35659 krueppel- 322 29
437426 AW136558 Hs 125246 ESTε 449 29
405528 C2002647 gι|4507721|ref|NP 003310 1| tit 603 29
442977 AW291731 Hs 144090 ESTε 423 29
433330 AW207084 Hs 132816 hypothetical protein MGC14801 1324 28
424275 AW673173 Hs 144505 DKFZP566F0546 protein 560 28
426667 AA770016 Hs 121192 ESTs 364 28
410202 AB023213 Hs 60177 KIAA0996 protein 300 28
428080 AI198656 Hs 98330 ESTs 409 28
427252 AA400069 Hs 97757 hypothetical protein FLJ13031 434 28 458255 AW140126 Hs 132357 ESTs 323 28
433612 AF078164 Hs 61188 Homo sapiens Ku70 binding protein (KUB3) 395 28
440582 AA993337 Hs 129082 ESTs 529 28
435566 A1457958 Hs 80464 hepatitis B virus x interacting protein 328 28
433771 A1028794 Hs 112684 ESTs 336 28
447924 AI817226 Hs 313413 ESTs, Weakly similar to T23110 hypotheti 530 28
426703 AI221893 Hs 121549 ESTs 393 28
430251 AA609246 Hs 181451 ESTs 404 28
427184 AI969361 Hs 180471 ESTs 678 28
439909 AW450062 Hs 187134 ESTs, Moderately similar to AF2637421 g 365 28
448885 AW003686 Hs 30325 ESTs, Highly similar to AF200923 1 testi 334 27
450340 AA442322 Hs 60288 ESTs 539 27
428100 AW665592 Hs 190413 ESTs 532 27
449333 AI203021 ESTs 435 27
429861 AI989571 Hs 99510 ESTs 3 28 27
426622 AL044400 Hs 25371 ESTs, Weakly similar to A37232 mucin, tr 538 27
427256 AL042436 Hs 97723 ESTs 408 27
408407 AF214680 Hs 44685 C3HC4-lιke zinc finger protein 327 27
403328 Target Exon 426 27
436264 AA707457 Hs 120014 ESTs 3 58 27
427104 AA398187 Hε 104682 ESTs, Weakly similar to mitochondnal ci 368 27
426640 AI200961 Hε 98104 ESTs 460 27
428789 AW296167 Hs 91930 ESTs 423 27
435274 AA887547 Hε 150905 ESTs 425 27
426612 AA922067 Hε 184185 ESTs 7 17 27
435110 N42688 Hε 81001 F-box only protein 25 485 27
433792 AA778661 ESTs 406 27
423278 AL117627 Hε 126289 Homo sapiens mRNA, cDNA DKFZp434B115 (fr 304 27
427284 AA400298 Hε 144696 ESTs 581 26
423375 Z94277 Hs 127689 type 1 protein phosphatase inhibitor 336 26
422362 Z46967 Hs 115460 calicin 472 26
439993 T18864 Hs 144924 seπne/threon e protein kinase SSTK 503 26
409364 AI480252 Hs 137368 ESTs 722 26
419224 NM 012189 Hs 314452 fibrousheathin II 1386 26
428915 AI041278 Hs 87908 Snf2-related CBP activator protein 473 26
427181 A1183653 Hs 27888 ESTε, Weakly similar to ALU1 HUMAN ALU S 421 26
442122 AI932330 ESTs 307 26
424812 AF059252 Hε 153299 DOM-3 (C elegans) homolog Z 380 26
430956 AI183529 Hs 2706 glutathione peroxidase 4 (phospholipid h 3 19 26
427234 AA399667 Hs 104675 ESTs 343 26
423005 AL080148 Hs 123004 DKFZP434B204 protein 353 26
428214 AA936282 Hs 120397 ESTs 414 26
452613 AA461599 Hs 23459 ESTs 778 26
410380 AL133068 Hs 62880 novel protein similar to mouse MOV10 345 26
452537 AW247390 Hs 77735 hypothetical protein FLJ11618 343 26
401712 Target Exon 451 26
429186 BE503443 Hs 112095 hypothetical protein DKFZp434F1819 590 26
438124 AA778610 Hs 122045 ESTs 343 26
422937 U03270 Hs 122511 centπn, EF-hand protein, 1 360 26
410279 BE271977 Hs 61809 hypothetical protein FLJ14117 436 26
428625 W87565 Hs 18566 ESTε 529 26
433439 AA431176 Hs 133230 πbosomal protem S15 350 25
433760 AW592321 ESTs 326 25
431219 AI190773 Hs 127204 ESTs, Weakly similar to similar to CR16, 510 25
411773 NM 006799 Hε 72026 protease, senne, 21 (testism) 807 25
453468 W00712 Hε 32990 DKFZP566F084 protein 3 56 25
445158 AI992108 Hε 127206 ESTs 360 25
440860 R10482 Hε 132876 ESTs 426 25
452420 BE564871 Hs 29463 centππ, EF-hand protein, 3 (CDC31 yeast 395 25
433281 N48673 Hs 146037 hypothetical protein DKFZp434C135 568 25
429369 AI269514 Hs 129802 ESTs 349 25
433949 AI674766 Hs 112877 ESTε 515 25
427668 AA298760 Hs 180191 hypothetical protein FLJ14904 1046 25
414708 AA393379 Hs 97415 ESTε, Weakly similar to T33068 hypotheti 387 25
408485 AW274294 Hs 144092 ESTs, Weakly similar to A Cham A, Sxch 610 24
412869 AA290712 Hs 82407 CXC chemokine ligand 16 564 24
426956 AA393673 ESTs, Weakly similar to ALU5.HUMAN ALU S 468 24
429152 AA447209 Hε 99099 Homo sapieπε NYD-SP28 mRNA, complete cdε 434 24
426247 U92992 Hs 98834 ESTs 540 24
427589 T19219 Hs 97978 hypothetical protein MGC4766 similar to 340 24
429099 BE439952 Hs 196177 phosphorylase kinase, gamma 2 (testis) 585 24
453353 U33055 Hs 32959 G protein-coupled rxeptor k ase 2 (Dro 482 24
413372 H55532 tubulin, alpha 2 932 24
411737 AW160339 Hs 71791 hypothetical protein 5 26 24
453868 NM 014433 Hs 35984 rhabdoid tumor deletion region protein 1 305 24
427098 AA398161 Hs 97602 ESTs 321 24
427165 AA429709 Hs 99336 ESTs, Weakly similar to T15446 hypotheti 427 24
425808 AA364109 Hs 177990 ESTε 780 24
444790 AB030506 Hs 11955 B9 protein 332 24
426718 AA383555 Hs 126413 ESTε 420 24
411441 AL042355 Hs 70202 WD repeat domain 10 614 24
450852 AI983354 Hs 7740 oxyεterol binding protein like 1 497 23
427054 AA421240 Hs 97570 ESTε 310 23 438633 AI653327 Hs 123501 ESTs 346 23
427199 AW015836 Hs 292919 ESTs 4 31 23
440182 AA868919 Hs 250110 ESTε 3 03 23
435517 AA928626 Hs 130177 ESTs 364 23
446309 BE044261 Hs 149774 ESTs 3 52 23
420338 AA825595 Hs 88269 Homo sapiens, clone MGC 17339, mRNA, com 4 23 23
433829 AI190715 Hs 102021 ESTs 6 08 23
429485 AW197086 Hs 99338 ESTε 314 23
423058 AW964568 Hs 111591 ESTs 336 23
433822 AI218609 Hs 112772 ESTs 3 83 23
442268 BE278064 Hs 8179 hypothetical protein, clone 2746033 3 00 23
434298 AA860090 Hε 116290 ESTs 371 23
440720 AW662776 Hs 336943 Human DNA sequence from clone RP11-60H7 308 23
427554 AW246578 Hs 179615 hypothetical protein FLJ10058 3 39 23
414251 AL042306 Hs 97689 VASA protein 11 25 23
430254 AI809520 ESTs 3 27 23
437418 AI478954 Hs 59459 ESTs 343 22
437522 AA983844 Hs 121383 ESTs 4 15 22
422808 AA449014 Hs 121025 chromosome 11 open reading frame 5 309 22
436695 AA725655 Hs 120480 ESTε 5 26 22
422247 U18244 Hs 113602 εolute earner family 1 (high affinity a 678 22
421625 AA405386 Hs 178004 ESTs 322 22
434807 AA364183 Hs 323443 hypothetical protein FLJ11806 5 51 22
428174 AA913321 Hs 126778 ESTs 3 09 22
409735 AL035295 Hs 56175 H sapiens gene from PAC 106H8, similar t 311 22
444467 AI150368 ESTs 381 22
433832 AA918018 Hs 172516 ESTs 694 22
440036 AW593295 Hs 210956 ESTs 5 87 22
415240 AA161411 Hs 58668 chromosome 21 open reading frame 57 366 22
432538 BE258332 Hs 278362 male-enhanced antigen 358 21
440882 AI205777 Hs 129538 ESTε 3 83 21
436605 AI187742 ESTs 341 21
422990 AF035620 Hs 122764 BRCA1 asεociated protein 566 21
432174 AW590264 Hs 132806 ESTs 305 2 1
409267 NM 012453 Hs 52515 transducin (beta) like 2 546 21
423021 AL036111 Hs 292767 ESTs 3 87 21
439012 BE383814 Hs 6455 RuvB (E coli homolog) like 2 525 2 1
433812 AA725026 Hε 97165 ESTs, Weakly similar to T31611 hypotheti 362 21
456924 AI631510 Hs 196956 ESTs, Highly similar to match to EST AA3 438 21
437249 AA432202 Hs 103147 hypothetical protein FLJ21347 338 2 1
426038 AA368101 Hs 99052 ESTs 303 2 1
427065 AA397903 Hs 236635 gb zt89f12 r1 Soares testis NHT Homo sap 323 21
428824 W23624 Hs 173059 ESTs 307 21
428224 X54017 Hε 183088 acrosin 3 18 21
436954 AA740151 Hε 130425 ESTs 320 21
444470 AA412195 Hs 13740 ESTs 427 21
457579 AB030816 Hs 36761 HRAS-like suppressor 5 30 21
427886 AA417083 Hs 104789 ESTs 349 21
439273 AW139099 Hs 269701 ESTs 383 21
434318 AW207552 Hs 116328 ESTs, Weakly similar to A39564 traπscnp 401 21
427015 AA397520 ESTs 428 21
421598 AW630942 Hs 106061 RD RNA-bindmg protein 330 2 1
427236 AA399959 Hs 148271 ESTs 307 21
434520 AA205273 Hs 177011 hypothetical protein 3 19 20
456051 T85626 Hε 76239 hypothetical protein FU20608 3 11 20
418322 AA284166 Hs 84113 cyclm-dependent kinase inhibitor 3 (CDK 841 20
451807 W52854 hypothetical protein FU23293 similar to 352 20
448984 AW751955 Hs 22753 hypothetical protein FLJ22318 473 20
420484 W32963 Hs 98289 VRK3 for vxcmia related kinase 3 386 20
414181 AK000476 Hs 75798 hypothetical protein 333 20
424558 AF038847 Hs 150490 FK506-bmdιπg protein 6 (36kD) 770 20
TABLE 54B
Pkey Unique Eos probeεet identifier number CAT number Gene cluster number
Accesεion Genbank xceεεion numberε
Pkey CAT Number Accession 428618 2668.1 BC017998 BI826643 BG715794 BG722697 BI460787 BG773459 H52859 AI652853 AI990773 AW665193 AW340601 AA913806 AI337099
BE045942 AW572790 AW515652 H15004 AA909115 BI465310 BI462024 BI561578 BI463075 BG722527 R86003 BG623286 H15003 BI562131
BG435272
426599 10110.1 BE736800 BM471423 AL557221 BG763302 BF742196 BF991016 BG200112 BF920027 BG576409 BG332214 BI830957 AI827504 AW183574
AI805171 AI126491 AA448257 AI090641 AW183329 AA994873 AI203663 BE041513 AA382260 AA382261 AL554887 BE273483
426930 1310779 1 AI809889 AA393442 AI150574 AI200886 AI221692 AA608977 AA813213
434317 599587.1 AI209094 AI377740 AW117382 AW182289 AI674095 AW188019 AA897352 AA931314 AA923336 AW665317 AA629314 AA776691 AA906846
AA974625 AA884357 AI808590
426620 142987.1 AL042392 AI147451 AA758821 AW450252 AA399310 AI656343 AI636668 AW515660 AI190733 AI025812 AA723645 AA709253 AA725709
AA398244 AA382463 AI139837
419350 13086.1 AI218809 BC014609 BG724383 AI024359 AA904573 AI138595 AA868685 AI768931 BI828436 BG717350 BG719800 AW182303 AA448181
BI826670 BI827131 BI830254 BI824155 BI831745T19190 BI830415
440822 532606 1 BG207562 BG192113 AA977616 AW274024 AI554897 AI221379 AA969158 AA906867 AI873494 AI015039
421938 863689.1 AA412383 AA300675 BG773248 AA412243 AA405951 442589 33097 2 NM.004157 X14968 BG480488 BE409869 BG723898 BG476313 AU121626 BE386516 AI969297 AW172340 AA889668 R23436 AI015037
BE250558 BF590945 AW385993 BF983000 AA070235 AL556082 M78388 AW504473 AW370139 BG913697 BE899096 BG827945 BE741233
AI015465 AW370169 BE297350 AA093249
436588 2470836 1 AI122828 AA909991 AA759233
431986 76926 1 AL591713 BF197609 AI985094 AW448916 AI243277 AL449630 AL449629
420431 29290 1 AW241405 AW205071 AI671586 AI652354 AI638465 AW590359 AW662771 AW594067 BE502532 AI218894 BE466416 BF056295 A1247366
436601 10131 1 AI990484 A1917746 AW665925 AI216456 AW182169 AA969884 AA723888 AI018419
408415 4581_6 BI602176 BI603138 BI459895 BI755030 AW418788 AA883999 AA724858 AI480311 AW196355 AI004813 AI651117 BE814363 AW589856
AA448124 AA447982 BI461166 AA405629
427748 1372622 1 AI208966 AA421041 AA815377 AA411954
440115 34 3 BF980396 R51074 BF979883 AI539370 BM128735 AA993397 AI611039 AW593985 R41808
428524 1382184 1 AI208080 AA442862 AA429772
440933 980517.1 AI125404 A 593312 AI247364AI208217AA910021 A1915307
427829 1373537 1 AI190292 AI188225 AA416673 AA416596 AA952888 AA972172 AA906874
438735 10316 1 M76676 NM.022571 BG772522 BF516449 AI537485 AW517245 BF762536 AA634446 AW196331 AI203035 BG722281
449333 36378.1 AK056320 AL522040 BI793043 AW071691 AI433682 AA865414 AA702684 BI792794 H96879 R52351 AA211126 AA442875 N25725 AA482563
N33446 N25222 Z41110 N26507 N73447 N24077 N20492 AW275550 H99619 AL518306 AL522041 AW959849 AL518307 AA725907 AI655113
AI309906 F10184 BM451081 BE257595 BG721625 BI828509 BG700470 F12568 Z45396 BI829288 AA364618 AA364851 AA421448T74231
R52350 AA482415 AI203021 T88948 AI565842
433792 2204621 1 AI024286 AA769898 AA778661 AA868972 AA609524
442122 2684549 1 AI932330 AI190707 AI376782 AA976847
433760 584982.T AA609179 AW592321 AA758282 AI214437 AW072537 AA781937
426956 657337 1 BI831486 AW190479 AI472793 AA460217 AA459937 BF082576 AA393673 AA398702
413372 32896.1 NM_006001 L11645 AI205604 A1207994 AI187362 AA709190 BI462421 BG772170 BG722772 AA436991 BG771655 BI553260 BF126025
BF125857 BI462670 BG724164 BI562424 BG721652 BI559662 BG722455 BI596415 BG717561 BG722138 BG773507 BG720572 C03867 AI016802
AL042663 AA770436 AA435720 T19365 AA626698 AA759057 AI208021 BF507844 AI208058 AA412719 AA426374 AI208775 AA977217 AA758055
F34585 AA180062
430254 13102.1 BG700885 AA868017 AW341719 AA971332 AI688794 Z20462 AI808145 AW665263 AA884952 AA906136
444467 1008400 1 AW663704 AH 50368 AI216464
436605 1008207 1 AI125340 AI125684 AI377949 AI126470 AI218351 AW665355 AI243952 AW663454 AI240603 AI187742 AA884214 AA723933
427015 683123 1 AA857437 AI968733 AI968938 AA992784 AA397520 AW235244
451807 17758 2 BM479185 AL552795 AL577722 BF038888 BM127617 BF510346 AW450652 AA865478 AW449519 BM127314 AI806539 AW449522 AA993634
AI827626 AA904788
TABLE 54C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand Nt position
401979 2828778 Minus 75693-75851,76977-77112
406409 9256364 Minus 141101-141256
401741 2982169 Plus 196686-196823,200241-200381
406378 9256142 Minus 126408-126800
405264 7329374 Plus 28556-28684
401692 3540172 Plus 26365-26510
403783 8081824 Plus 128412-128635
404271 9828129 Minus 56392-57645
401798 6730720 Plus 22831-23448
402857 9801539 Plus 13402-14133
405528 9581957 Minus 22418-22687
403328 8469086 Minus 120428-120703
401712 6682593 Minus 76410-76527,76692-76829,78737-78866,8024
TABLE 55A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcesεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of non-seminomatous mixed germ cell testicular cancer compared to normal adult testicular tissues
Pkey ExAccn UnigenelD Unigene Title R1
416680 AW245540 Hs 79516 brain abundant, membrane attached εignal
423961 D13666 Hs 136348 peπostιπ(OSF-2os) 4330
412948 BE243313 Hs 334851 LIM and SH3 protein 1 4250
428928 BE409838 Hs 194657 cadhenn 1, type 1, E-cadheππ (epitheli 3680
424247 X14008 Hs 234734 lysozyme (renal amyloidosis) 2980
414438 AI879277 Hs 76136 thioredoxm 2940
406658 AI920965 Hs 77961 major histxompatibility complex, class 2925
446899 NM 005397 Hs 16426 podocalyxin like 2870
411573 AB029000 Hs 70823 KIAA1077 protein 2840
432730 AI066520 Hs 131358 ESTs 2800
418870 AF147204 Hs 89414 chemokine (C-X-C motif), rxeptor 4 (fus 2800
444381 BE387335 Hs 283713 ESTs, Weakly similar to S64054 hypotheti 2790
446619 AU076643 Hs 313 secreted phosphoprotein 1 (osteopontm, 2680
447526 AL048753 Hs 303649 small inducible cytokine A2 (monxyte ch 2500
418174 L20688 Hs 83656 Rho GDP dissxiation inhibitor (GDI) bet 2415 406856 AW515336 Hs 29797 πbosomal protein L10 2366
414682 AL021154 Hs 76884 inhibitor of DNA binding 3, dominant neg 2360
440440 Z28925 HS 7188 sema domain, immunoglobulin domain (Ig), 2360
417139 M69043 Hs 81328 nuclear factor of kappa light polypeptid 2235
417426 NM 002291 Hs 82124 laminin, beta 1 2160
407862 BE548267 Hs 337986 Homo sapiens cDNA FLJ10934 fis, clone OV 2155
439180 AI393742 Hs 199067 v-erb b2 avian erythroblastic leukemia v 2150
413787 AI352558 tyrosine 3-moπooxygeπase/tryptophan 5 mo 2150
408669 AI493591 Hs 78146 platelet/endothelial cell adheεioπ molx 2090
412636 NM 004415 desmoplakm (DPI, DPII) 2090
414092 Z14244 Hs 75752 cytochrome c oxidase subunit Vllb 2030
414587 NM 004862 Hs 76507 LPS induced TNF-alpha factor 1945
412915 AW087727 Hs 74823 NM_004541 Homo sapieπε NADH dehydrogenas 1930
406648 AA563730 Hs 277477 major histocompalibility complex, clasε 1910
412247 AF022375 Hs 73793 vaεcular endothelial growth factor 1745
446108 AL036596 Hs 42322 A kinase (PRKA) anchor protein 2 1740
424800 AL035588 Hs 153203 MyoD family inhibitor 1720
413063 AL035737 Hs 75184 chitmase 3-lιke 1 (cartilage glycoprote 1690
415314 N88802 Hs 5422 glycoprotein M6B 1680
406656 M16714 Hs 89643 major histxompatibility complex, class 1675
426295 AW367283 zinc finger protein 6 (CMPX1) 1625
406820 AI223958 Hs 108124 nbosomal protein S4, X-lmked 1600
444562 AA186715 Hs 336429 RIKEN CDNA 9130422N19 gene 1585
417088 M54915 Hs 81170 pιm-1 oncogene 1560
449338 H73444 Hs 394 adreπomedulliπ 1551
444784 D12485 Hs 11951 ectonucteotide pyrophosphatase/phosphodi 1533
414420 AA043424 Hs 76095 immediate early response 3 1530
425543 R23313 Hs 334895 nbosomal protein L10a 1510
452679 Z42387 Hs 83883 transmembrane, prostate androgen induced 1500
420754 W79431 Hs 346911 πbosomal protein L22 1492
410397 AF217517 Hs 63042 DKFZp564J157 protein 1486
417640 D30857 Hs 82353 protein C receptor, endothelial (EPCR) 1470
415899 X78992 Hs 78909 butyrate response fxtor 2 (EGF-response 1460
406786 AW161678 Hs 111334 ferntm, light polypeptide 1457
422105 AI929700 Hs 111680 endosulfine alpha 1457
422714 AB018335 Hs 119387 KIAA0792 gene product 1425
444051 N48373 Hs 10247 activated leucxyte cell adhesion molecu 1405
426996 AW968934 Hs 173108 Homo sapiens cDNA FU21897 fis, clone H 1400
445863 R12234 Hs 13396 Homo sapiens clone 25028 mRNA sequence 1400
429614 AI371172 Hs 211539 hypothetical protein MGC4248 1395
410185 BE294068 Hs 737 immediate eariy protein 1385
409038 T97490 Hs 50002 εmall inducible cytokine subfamily A (Cy 1360
410611 AW954134 Hs 20924 KIAA1628 protein 1360
448588 AI970276 Hs 156905 KIAA1676 1340
421406 AF179897 Hs 104105 Meis (mouse) homolog 2 1310
420962 NM.005904 Hs 100602 MAD (motherε against decapentaplegic, Dr 1300
425234 AW152225 Hs 165909 ESTs, Weakly similar to I38022 hypotheti 1300
452322 BE566343 Hs 28988 glutaredox (thioltransferase) 1300
454413 AI653672 Hs 40092 PNAS-123 1290
415221 W07418 Hs 78225 annexm A1 1289
425535 AB007937 Hs 158287 KIAA0468 gene product 1248
450000 AI952797 Hs 10888 hypothetical protein FU21709 1245
418151 AA864238 Hs 83583 xtin related protein 2/3 complex, subun 1240
414799 AI752416 Hs 77326 insulin like growth factor binding prote 1219
412025 A1827451 Hs 24143 Wiskott-Aldπch syndrome protein interx 1212
445055 BE512856 Hs 109051 SH3 domain binding glutamic xid πch pr 1207
412490 AW803564 Hs 288850 Homo sapiens cDNA FLJ22528 fis, clone H 1190
408437 AW957744 Hs 278469 Ixπmal proline πch protein 1180
430542 AI557486 Hs 119122 πbosomal protein L13a 1151
424670 W61215 Hs 116651 epithelial V-like antigen 1 1150
432409 AA806538 Hs 130732 KIAA1575 protein 1150
425945 AW410669 Hs 164280 solute earner family 25 (mitxhondπal 1144
425996 W67330 hypothetical protein AL110115 1140
449961 AW265634 Hs 133100 ESTs 1140
435522 N64214 Hs 9774 synovial εarcoma tranεlxation gene on c 1125
407179 AA206465 thymosin, beta 4, X chromosome 1121
412623 R28898 Hs 74170 metallothioπem 1E (functional) 1110
429978 AA249027 πbosomal protein S6 1110
450377 AB033091 KIAA1265 protein 1110
418509 AB028624 Hs 85539 ATP synthase, H transporting, mitxhondr 1110
440869 NM 014297 Hs 7486 protein expresεed in thyroid 1100
417144 AA382104 Hs 81337 iectin, galxtoside binding, soluble, 9 1100
451106 BE382701 Hs 25960 N-MYC oncogene 1093
426552 BE297660 Hs 170328 moesin 1091
433423 BE407127 Hs 8997 heat shock 70kD protein 1 A 1090
442622 NM 000435 Hs 8546 Notch (Drosophila) homolog 3 1080
407951 W77762 Hs 79015 antigen identified by monxlonal antibod 1080
449944 AF290512 Hs 58215 Homo sapienε, Similar to rhotekin, clone 1075
423673 BE003054 Hs 1695 matnx metalloprotemase 12 (macrophage 1070
435056 AW023337 Hs 5422 glycoprotein M6B 1070
406743 AA911568 Hs 279860 tumor protein translationally-controlle 1070
422627 BE336857 Hs 118787 transforming growth factor, beta induced 1065
420676 AI434780 Hs 4248 vav 2 oncogene 1060 444060 AA340277 Homo εapienε cDNA FLJ20167 fis, clone CO 1060
420028 AB014680 Hs 8786 carbohydrate (N-acetylglucosamιπe-6-O) ε 1050
436075 BE090176 Hs 179902 transporter-like protein 1030
450139 AK001838 serum/glucxorticoid regulated kmase 1030
427691 AW194426 Hs 20726 ESTs 1026
424201 L33075 Hs 1742 IQ motif containing GTPase xtivatmg pr 1015
448412 AI219083 Hs 42532 ESTs, Moderately similar to ALU8_HUMAN A 10 10
440528 BE313555 Hs 7252 KIAA1224 protein 1006
423184 NM.004428 Hs 1624 ephπn-A1 1005
450847 NM 003155 Hs 25590 staπmocalcin 1 990
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 9 90
436876 AI124756 Hs 5337 isocitrate dehydrogenase 2 (NADP), mitoc 9 90
421395 D90084 Hs 1023 pyruvate dehydrogenase (lipoamide) alpha 989
435918 AF263538 Hs 86232 growth differentiation factor 3 9 89
411251 R19774 Hs 22835 HHGP protein 980
406791 AI220684 Hs 347939 hemoglobin, alpha 2 975
441187 AW195237 Hε 7734 hypothetical protein FU22174 975
425580 L11144 Hs 1907 galanin 960
420225 AW243046 Hs 282076 Homo sapiens mRNA for KIAA1650 protein, 960
413813 M96956 Hs 75561 teratxarcinoma-deπved growth fxtor 1 9 60
434280 BE005398 gb CM1-BN0116-150400-189 h02 BN0116 Homo 960
417944 AU077196 Hs 82985 collagen, type V, alpha 2 953
409963 AA133590 Hs 250857 calcium/calmodulm-dependent protein kin 951
428664 AK001666 Hs 189095 similar to SALL1 (sal (Drosophιia)-lιke 942
416926 H03109 Hs 263395 HT018 protein 941
456236 AF045229 Hs 82280 regulator of G-protem signalling 10 940
428065 AI634046 Hs 157313 ESTs 940
441455 AJ271671 Hs 7854 zinc/iron regulated transporter-like 939
410325 AB023154 Hs 62264 KIAA0937 protein 930
415189 L34657 Hs 78146 platelet/endothelial cell adhesion molec 9 30
454038 X06374 Hs 37040 platelet-deπved growth fxtor alpha pol 9 29
452568 AA805634 Hs 300870 Homo sapienε mRNA, cDNA DKFZp547M072 (fr 9 24
447211 AL161961 Hs 17767 KIAA1554 protein 922
422068 AI807519 Hs 104520 Homo sapienε cDNA FLJ13694 fiε, clone PL 9 20
418299 AA279530 Hs 83968 integnn, beta 2 (antigen CD18 (p95), ly 893
421379 Y15221 Hs 103982 εmall inducible cytokine subfamily B (Cy 890
429490 AI971131 Hs 23889 ESTs, Weakly similar to ALU7.HUMAN ALU S 890
422241 Y00062 Hs 170121 protein tyrosine phosphataεe, rxeptor t 8 90
449335 AW150717 Hs 345728 STAT induced STAT inhibitor 3 884
413886 AW958264 Hs 103832 similar to yeast Upf3, variant B 880
447471 AF039843 Hs 18676 sprouty (Drosophila) homolog 2 870
426215 AW963419 Hs 155223 stannixalcm 2 870
446627 A1973016 Hs 15725 hypothetical protein SBBI48 860
431639 AK000680 Hs 266175 phosphoprotein asεociated with GEMs 860
433412 AV653729 Hs 8185 CGI-44 protein, sulfide dehydrogenase Ii 8 60
410023 AB017169 Hs 57929 slit (Drosophila) homolog 3 850
445245 AB032973 Hs 12461 LCHN protein 8 50
448776 BE302464 Hs 30057 MRS2 (S cerevιsιae)-lιke, magnesium hom 840
453856 AA804789 Hs 19447 PDZ-LIM protein mystique 835
410143 AA188169 KIAA1191 protein 835
414591 AI888490 Hs 55902 ESTs, Weakly similar to ALU8 HUMAN ALU S 830
433208 AW002834 Hs 24095 ESTs 830
423753 Y11312 Hs 132463 phosphoιnosιtιde-3-kιnase, class 2, beta 825
432559 AW452948 Hs 257631 ESTs 8 20
450581 AF081513 Hs 25195 TGF-beta4 810
450157 AW961576 Hs 60178 ESTs 8 10
444795 AI193356 Hs 160316 ESTs 810
400288 X06256 Hs 149609 integπn, alpha 5 (fibronxtin receptor, 805
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 800
420059 AF161486 Hs 94769 RAB23, member RAS oncogene family 800
419970 AW612022 ESTs 8 00
411975 AI916058 Hs 144583 ESTs 795
446525 AW967069 Hs 211556 hypothetical protein MGC5487 7 90
451831 NM 001674 Hs 460 xtivatmg transcnption fxtor 3 790
437103 AW139408 Hs 152940 ESTs 790
432636 AA340864 Hs 278562 claudin 7 787
424687 J05070 Hs 151738 matrix metalloprotemase 9 (gelatmase B 784
419682 H13139 Hs 92282 paired-like homeodomain transcnption fa 780
407137 T97307 gb ye53h05 s1 Soares fetal liver εpleen 780
450147 AW373713 Hs 146324 CGI-145 protein 775
447188 H65423 Hs 17631 hypothetical protein DKFZp434E2135 770
449571 AW016812 Hs 200266 ESTs 770
429355 AW973253 Hs 292689 ESTs 770
446488 AB037782 Hs 15119 KIAA1361 protein 770
414774 X02419 Hs 77274 plasminogen xtivator, urokmase 769
422424 AI186431 Hs 296638 prostate differentiation fxtor 7 67
428818 AI131291 Hs 102308 potassium inwardly-rectifying channel, s 765
416078 AL034349 Hs 79005 protein tyroεme phosphataεe, rxeptor t 765
451812 X81889 Hs 152151 plakophilin 4 765
410315 AI638871 Hs 17625 Homo εapienε cDNA FLJ22524 fiε, clone H 760
452874 AK001061 Hs 30925 hypothetical protein FLJ10199 760
422746 NM.004484 Hs 119651 glypican 3 7 60
414020 NM.002984 Hs 75703 small inducible cytokine A4 (homologous 7 57 447674 BE270640 Hs 19192 cyclm-dependent kmase 2 7 57
426689 BE245550 Hs 171825 basic helix loop helix domain containing 7 55
444933 NM.016245 Hs 12150 retinal short-chain dehydrogenase/reduct 753
418329 AW247430 Hs 84152 cyεtathioniπe-beta synthase 750
425246 A1085561 Hs 155321 serum response factor (c fos serum respo 750
419223 X60111 Hs 1244 CD9 antigen (p24) 747
406776 T16206 Hs 237164 ESTs Highly similar to LDHH.HUMAN L LAC 744
401466 vesicle-asεociated membrane protein 4 743
435080 AI831760 Hs 155111 hypothetical protein FLJ14428 740
413686 AI469213 Hs 71404 ESTε 740
408605 AF025374 Hs 46465 T-cell immune regulator 1 740
408558 AW015759 Hs 235709 Homo sapiens mRNA, cDNA DKFZp667B0711 (f 730
444838 AV651680 Hs 208558 ESTs 7 30
409208 Y00093 integnn alpha X (antigen CD11C (p150) 7 28
427820 BE222494 Hs 180919 inhibitor of DNA binding 2 dominant neg 7 20
452924 AW580939 Hs 97199 complement component C1q receptor 7 15
436398 H87136 Hs 5174 ribosomal protein S17 715
443195 BE1 8235 Hs 193063 Homo sapienε cDNA FLJ14201 fiε, clone NT 710
437442 T85104 Hs 222779 ESTε, Moderately similar to similar to N 710
447735 AA775268 Hs 6127 Homo sapiens cDNA FLJ23020 fis clone L 7 10
401192 Target Exon 708
424503 NM.002205 Hs 149609 integnn, alpha 5 (fibronectin receptor, 708
402474 NM.004079 Homo sapiens cathepsin S (CTSS 700
449567 AI990790 Hs 188614 ESTs 700
448019 AW947164 Hs 195641 ESTs, Moderately similar to I38022 hypot 7 00
450506 NM 004460 Hs 418 fibroblast activation protein, alpha 7 00
430068 AA464964 gb zx80f10 s1 Soares ovary tumor NbHOT H 700
431427 AK000401 Hs 252748 Homo sapienε cDNA FLJ20394 fiε, clone KA 690
426440 BE382756 Hs 169902 solute earner family 2 (facilitated glu 687
442492 AA528489 Hs 234518 πbosomal protein L23 684
417365 D50683 Hs 82028 transforming growth factor, beta recepto 680
452436 BE077546 Hs 31447 ESTs, Moderately similar to A46010 X lin 6 80
431183 NM 006855 Hs 250696 KDEL (Lys Asp Glu Leu) endoplasmic retic 6 80
435684 NM.001290 Hs 4980 LIM domain binding 2 680
442685 AB033017 Hs 8594 KIAA1191 protein 679
413542 BE295928 Hs 75424 inhibitor of DNA binding 1 , dominant neg 677
411789 AF245505 Hs 72157 Adlican 676
441565 AW953575 Hs 303125 p53 induced protein PIGPC1 675
440268 BE270030 Hs 336959 Homo sapiens clone IMAGE 3677185 mRNA 674
444207 AI565004 cathepsin D (lysosomal aspartyl protease 672
408912 AB011084 Hs 48924 KIAA0512 gene product ALEX2 670
429500 X78565 Hs 289114 hexabrachioπ (tenascm C cytotxtm) 670
429469 M64590 Hs 27 glycine dehydrogenase (decarboxylatmg, 670
438915 AA280174 Hs 285681 Williams Beuren syndrome chromosome regi 670
430332 R51790 Hs 239483 Human clone 23933 mRNA εequence 670
413497 BE177661 gb RC1-HT059S-020300011-h02 HT0598 Homo 670
433271 BE621697 Hε 14317 nucleolar protein family A member 3 (HI 666
443351 AW016783 Hε 30799 Homo εapienε cDNA FU13471 fis, clone PL 665
406858 AI865720 Hs 29797 nbosomal protein L10 6 65
435748 AA699756 Hs 117335 ESTs 663
423024 AA593731 Hs 325823 ESTε, Moderately similar to ALU5.HUMAN A 662
422451 AA310753 Hs 42491 ESTs, Weakly similar to S65657 alpha-1 C- 662
424415 NM 001975 Hs 146580 enolase 2, (gamma neuronal) 661
434584 D57341 Hs 188361 Homo sapiens cDNA FLJ 12807 fis clone NT 660
442379 NM 004613 Hs 8265 transglutaminase 2 (C polypeptide, prote 655
424528 AW073971 Hs 238954 ESTs, Weakly similar to KIAA1204 protein 650
450294 H42587 Hs 238730 hypothetical protein MGC10823 645
417336 R70429 Hs 81988 disabled (Drosophila) homolog 2 (mitogen 645
418707 U97502 Hs 87497 butyrophilm, subfamily 3, member A2 643
402145 Target Exon 643
414662 AL036058 Hs 76807 major histxompatibility complex clasε 642
436860 H12751 Hs 5327 PR01914 protein 640
438962 BE046594 gb hn41c11 x1 NCI CGAP RDF2 Homo εapieπε 640
435937 AA830893 Hs 119769 ESTε 640
412645 AW444433 Hs 136061 Homo εapienε, Similar to hypothetical pr 640
446173 BE565849 Hs 14158 copine III 639
425875 AU077333 Hs 160483 erythrocyte membrane protein band 72 (ε 636
412093 BE242691 Hs 14947 ESTε 634
446921 AB012113 Hε 16530 εmall inducible cytokine εubfamily A (Cy 630
443523 AK001575 Hε 9536 hypothetical protein FLJ 10713 630
428311 NM.005651 Hε 183671 tryptophan 2,3-dιoxygenase 630
447519 U46258 Hε 339665 ESTs 630
445817 NM 003642 Hs 13340 histone xetyltraπsferase 1 6 30
434423 NM.006769 Hs 3844 UM domain only 4 6 30
434524 AA635931 Hs 249716 ESTs 6 30
441970 AW959918 Hs 73737 ESTs 630
433675 AW977653 Hs75319 ribonucleotide reductase M2 polypeptide 630
437374 AL359571 Hs 44054 πinein (GSK3B interacting protein) 625
437134 AA349944 Hs 42915 ARP2 (xtin related protein 2, yeast) ho 623
407284 AI539227 Hs 214039 hypothetical protem FLJ23556 620
426158 NM 001982 Hs 199067 v erb-b2 avian erythroblastic leukemia v 6 20
447029 AL137281 Hs 17110 Homo sapiens mRNA cDNA DKFZp434C2016 (f 620
417315 AI080042 Hs 180450 πbosomal protein S24 6 20 418840 AI821614 Hs 185831 ESTs 620
410668 BE379794 Hs 159651 hypothetical protein 616
425762 BE244076 Hs 159578 AT-hook transcnption fxtor AKNA 613
413840 AI301558 RNA binding motif protem, X chromosome 613
409493 AA386192 Hs 193482 Homo sapienε cDNA FLJ11903 fis, clone HE 612
450944 AA554989 εudD (suppressor of bιmD6, Aspergillus π 610
415825 Y18024 Hs 78877 inositol 1,45 tπsphosphate 3-kmase B 610
435538 AB011540 Hs 4930 low density lipoprotein receptor-related 610
429109 AL008637 Hs 196352 neutrophil cytosolic factor 4 (40kD) 610
418460 M26315 Hs 85258 CD8 antigen alpha polypeptide (p32) 610
408996 AI979168 Hs 344096 glycoprotein (transmembrane) πmb 610
432666 AW204069 ESTs, Weakly similar to unnamed protein 609
435812 AA700439 Hs 188490 ESTs 606
432805 X94630 Hs 3107 CD97 antigen 606
441283 AA927670 Hs 131704 ESTs 606
417632 R20855 Hs 5422 glycoprotein M6B 600
435905 AW997484 Hs 5003 KIAA0456 protein 600
425593 AA278921 Hs 1908 proteoglycan 1, sxretory granule 599
429083 Y09397 Hs 227817 BCL2-reIated protein A1 595
410598 AI817130 Hs 9195 Homo sapiens cDNA FLJ13698 fis, clone PL 595
425291 AA354572 gb EST62857 Jurkat T-cells V Homo sapien 595
449971 AA807346 Hs 288581 Homo εapiens cDNA FLJ14296 fis clone PL 593
451052 AA281504 Hs 24444 Homo sapiens cDNA FLJ22165 fis, clone H 590
447217 BE465754 Hs 17778 neuropilm 2 590
417228 AL134324 Hs 7312 ESTs 586
443963 AA878183 Hs 17448 Homo sapiens cDNA FLJ13618 fis clone PL 586
452382 N38902 Hs 211539 hypothetical protein MGC4248 584
427747 AW411425 Hs 180655 senne/threonme kinase 12 584
414483 R25513 Hs 10683 ESTs 582
428570 AA430321 Hs 293945 ESTs 581
443194 AI954968 matrix Gla protein 580
429582 AI569068 Hs 22247 ESTs 580
414405 AI362533 KIAA0306 protein 580
428342 AI739168 Homo sapienε cDNA FLJ13458 fis clone PL 580
437739 AW579216 Hs 264610 ESTs, Moderately similar to Ibd1 [H εapi 580
417018 M16038 Hs 80887 v-yes-1 Yamaguchi sarcoma viral related 580
442821 BE391929 Hs 8752 tranεmembraπe protein 4 577
434511 R28982 Hs 18106 ESTs 576
406745 AW511970 Hs 279860 tumor protein, translationally-coπtrolle 570
453187 AI161383 Hs 34549 ESTε, Highly similarto S94541 1 clone 4 570
453115 AW772041 Hs 18439 ESTs, Moderately similar to JC5238 galac 570
406857 AA613726 Hs 29797 πbosomal protein L10 569
418522 AA605038 Hs 7149 Homo sapiens cDNA FLJ21950 fis, clone H 568
444273 AI903474 Hs 230 fibromodulin 565
441623 AA315805 desmoglein 2 563
418300 AI433074 Hs 86682 Homo sapiens cDNA FLJ21578 fis, clone C 563
440099 AL080058 Hs 6909 DKFZP564G202 protein 560
434096 AW662958 Hs 75825 pleiomorphic adenoma gene-like 1 560
417621 AV654694 Hs 82316 interferon induced, hepatitis C-asεxiat 560
422610 AF153820 Hs 1547 potassium mwardly-rxtifying channel, s 560
438278 BE409248 Hs 57988 hypothetical protein FLJ22357 similar to 558
430451 AA836472 Hs 297939 cathepsin B 557
406699 L06505 Hs 182979 nbosomal protein L12 553
458965 AA010319 Hs 60389 ESTs 550
430592 AJ224864 Hs 9688 leukxyte membrane antιgen(IRCI) 550
433655 AL036559 Hε 3463 πbosomal protein S23 550
428471 X57348 Hs 184510 stratum 542
408822 AW500715 Hs 57079 Homo sapiens cDNA FLJ13267 fis, clone OV 540
417849 AW291587 Hs 82733 nidogen 2 540
408989 AW361666 Hs 49500 KIAA0746 protein 540
428467 AK002121 Hs 184465 hypothetical protein FLJ 11259 540
439971 W32474 Hs 301746 RAP2A, member of RAS oncogene family 540
449924 W30681 Hs 146233 Homo sapienε cDNA FU22130 fiε, clone H 540
406819 AA908472 gb og82a10 ε1 NCI_CGAP_Ov8 Homo sapiens 539
416655 AW968613 Hs 79428 BCL2/adenovιrus E1B 19kD-ιnterxtιng pro 536
451589 AA424791 Hs 5734 meningioma expressed antigen 5 (hyaluron 534
409327 L41162 Hs 53563 collagen, type IX, alpha 3 534
427968 AI857607 Hs 181301 cathepsin S 532
429307 AU076592 Hs 198951 jun B proto-oπcogene 530
424950 AA602917 Hs 156974 ESTs 530
410619 BE512730 Hs 65114 keratin 18 530
424408 AI754813 Hs 146428 collagen, type V, alpha 1 527
425430 BE185921 Hs 98073 ESTs, Moderately similar to Z195_HUMAN Z 527
411165 NM 000169 Hs 69089 galactosidase, alpha 526
406701 AA780613 Hs 62954 ferπtm, heavy polypeptide 1 526
435631 BE254086 Hs 29647 uncharacteπzed hematopoietic stem/proge 524
418905 BE539674 xtinm, alpha 4 523
449303 AK001495 Hs 23467 hypothetical protein FLJ10633 522
'440703 AL137663 Hs 7378 Homo sapienε mRNA, cDNA DKFZp434G227 (fr 520
430314 AA369601 Hs 239138 pre B-cell colony-enhancing factor 520
444930 BE185536 Hs 301183 molecule possessing ankyππ repeats indu 520
430598 AK001764 Hs 247112 hypothetical protein FLJ 10902 520
407254 AW129401 Hs 181165 eukaryotic translation elongation fxtor 520 409604 AW444448 Hs 49124 ESTs 5 20
432581 AU076465 Hs 278441 KIAA0015 gene product 5 16
430556 AW967807 Hs 13797 ESTs 5 16
431315 AW972227 Hs 163986 Homo sapiens cDNA FLJ22765 fiε, clone K 516
425190 AW028302 Hs 155079 protein phosphatase 2, regulatory subuni 5 15
454227 AW963897 Hs 44743 KIAA1435 protein 5 15
429367 AB007867 Hs 278311 plexm B1 512
452191 AU076408 Hs 28309 UDP-glucose dehydrogenase 511
419073 AW372170 Hs 183918 Homo sapieπε cDNA FLJ12797 fis clone NT 511
442295 AI827248 Hs 224398 Homo sapiens cDNA FLJ11469 fis clone HE 5 10
443030 R68048 Hs 9238 hypothetical protein FLJ23516 510
421878 AA299652 Hs 111496 Homo sapiens cDNA FLJ11643 fis clone HE 5 10
424875 AH 87945 Hs 199310 ESTs 510
427641 AI270591 Hs 146116 ESTs 5 10
442806 AW294522 Hs 149991 ESTs 510
442495 AI184717 ESTs 5 10
439941 AI392640 Hε 18272 ammo acid transporter system A1 5 10
444981 AW855398 Hs 12210 hypothetical protein FLJ13732 similar to 509
452472 AW957300 Hs 294142 ESTs Weakly similarto C55663 oligodend 507
418117 AI922013 Hs 83496 linker for xtivation of T cells 506
431824 AW972842 gb EST384937 MAGE resequences MAGL Homo 506
417558 AF045229 Hε 82280 regulator of G protein signalling 10 506
410570 AH 33096 Hε 64593 ATP synthaεe, H transporting, mitochondr 503
431805 NM.014053 Hs 270594 FLVCR protein 500
430333 S70114 Hs 239489 TIA1 cytotoxic granule-assxiated RNA bl 500
428494 AA233439 Hs 184634 hypothetical protein FLJ20005 500
419641 BE170548 Hs 118190 Homo sapiens cDNA FLJ21081 fis clone C 500
443634 H73972 Hs 134460 ESTs 5 00
452852 AK001972 Hs 30822 hypothetical protein FLJ11110 500
444621 AA298065 Hs 11465 glutathione S tranεferase like, glutathi 497
422200 AA080895 Hs 347969 cytochrome c oxidase subunit IV 495
416003 X98001 Hs 78948 Rab geranylgeranyltransferase, beta εubu 494
425428 AL110261 Hs 157211 DKFZP586B0621 protein 494
452063 R53185 Hs 32366 ESTε, Weakly similar to TWST.HUMAN TWIST 493
414821 M63835 Hs 77424 Fc fragment of IgG high affinity la re 493
429558 AI391454 Hs 207251 nucleolar autoantigen (55kD) similar to 492
432588 X92715 Hs 3057 zinc finger protein 74 (Cos52) 492
433162 AI025842 ESTs 492
406797 AI432224 nbosomal protein L6 491
412347 AW970026 Hε 73818 ubiquiπol-cytochrome c reductase hinge p 490
422392 NM.005908 Hs 115945 mannoεidase beta A, lysosomal 490
447197 R36075 gb yh88b01 s1 Soareε placenta Nb2HP Homo 490
447832 AI433357 ESTε 490
420932 AW374605 Hs 11607 ESTs Weakly similar to T21697 hypotheti 490
413593 AA205248 gb zq78c12 r1 Stratagene hNT neuron (937 490
451658 AW195351 Hs 250520 ESTs, Moderately similarto I38022 hypot 490
441224 AU076964 HS 7753 calumenin 490
408067 BE244580 Hs 342307 hypothetical protein FLJ 10330 490
424971 AA479005 Hs 154036 tumor suppressing subtransferable candid 490
417308 H60720 Hs 81892 KIAA0101 gene product 490
438763 AI583207 Hs 99029 CCAAT/enhancer binding protein (C/EBP), 489
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 489
414191 AW250089 Hs 75807 PDZ and LIM domain 1 (elfin) 488
421748 NM 014718 Hs 107809 KIAA0726 gene product 487
427486 AA974433 fibroblast growth fxtor 4 (hepaπn sxr 486
424263 M77640 Hs 1757 L1 cell adhesion molxule (hydrocephalus 482
406867 AA157857 Hs 182265 keratin 19 481
449378 AW664026 Hs 59892 ESTε 481
427202 BE272922 Hε 173936 interieukin 10 rxeptor, beta 480
418945 BE246762 Hs 89499 arxhidonate 5-lιpoxygeπase 480
448966 AW372914 Hs 86149 phosphomoεitol 3-phosphate-bιndιng prot 480
426711 AA383471 Hs 343800 conserved gene amplified in oεteosarcoma 480
433681 AI004377 Hs 200360 Homo sapiens cDNA FLJ 13027 fis clone NT 479
441321 H17182 Hs 7771 B-cell assxiated protein 475
448896 AL157484 Hs 22483 Homo sapiens mRNA, cDNA DKFZp762M127 (fr 475
447232 AW499834 Hs 327 interieukin 10 receptor, alpha 473
449317 AW293413 Hε 132906 19A24 protein 473
436372 AW972301 Hs 310286 ESTs 471
422082 AA016188 Hs 111244 hypothetical protein 470
432465 D56165 Hs 275163 non metastatic cells 2, protein (NM23B) 470
417924 AU077231 Hs 82932 cyclin D1 (PRAD1 parathyroid adenomatos 470
446659 AI335361 Hs 226376 ESTs 470
414829 AA321568 Hs 77436 plxkstππ 470
418036 Z37976 Hs 83337 latent transforming growth factor beta b 470
417677 NM 016055 Hs 82389 CGI-118 protein 470
443559 AI076765 Hs 269899 ESTs Moderately similar to ALU8.HUMAN A 470
423766 AA303799 Hs 300141 πbosomal protein L39 470
432407 AA221036 Hs 13273 gb zr03f12 r1 Stratagene NT2 neuronal pr 469
453485 BE620712 Hs 33026 hypothetical protein PP2447 467
452973 H88409 Hs 40527 ESTs 467
427816 AA159248 Hs 180909 peroxiredoxin 1 467
406794 AI890243 πbosomal protein L6 466
449475 AI348027 Hs 108557 hypothetical protein PP1057 465 427157 U51166 Hs 173824 thymme DNA glycosylase 464
425410 AA310974 Hs 156828 Homo sapiens cDNA FLJ10522 fis, clone NT 462
407874 A1766311 Hs 289047 Homo sapienε cDNA FLJ14059 fis, clone HE 461
417535 AA203569 Hs 191482 ESTs 461
421818 AW992976 Hs 50098 NM 002489 Homo sapiens NADH dehydrogeπas 461
408491 AI088063 Hs 7882 ESTε 460
428398 AI249368 Hs 98558 ESTε 460
410295 AA741357 nidogen (enactin) 460
407198 H91679 gb yv04a07 ε1 Soares fetal liver spleen 460
440327 R12581 Hε 191146 ESTs 460
417353 AA375752 Hε 348140 Homo sapiens mRNA cDNA DKFZp586F1822 (f 460
426141 C05886 Hε 293972 ESTs 460
412922 M60721 Hs 74870 H20 (Drosophιla)-lιke homeo box 1 459
434449 AW953484 Hs 3849 hypothetical protein FLJ22041 similarto 458
416987 D86957 Hs 80712 KIAA0202 protein 457
418883 BE387036 Hs 1211 acid phoεphatase 5 tartrate resistant 457
416581 H66276 Hs 108288 ESTs 456
440983 M20681 Hs 7594 solute earner family 2 (facilitated glu 456
450988 BE618571 Hs 429 ATP synthase, H transporting, mitochondr 456
413663 BE247585 Hε 75462 BTG family, member 2 4 55
410342 R31350 Hs 743 Fc fragment of IgE high affinity I, rx 454
424321 W74048 Hs 1765 lymphocyte-specific protein tyrosine k 453
453330 AI268081 Hs 342389 peptidylprolyl isomerase A (cyclophilin 452
417750 AI267720 Hs 260523 εynovial sarcoma, translocated to X chro 451
440774 AI420611 Hs 153934 ESTs 451
422693 BE300073 Hs 279860 tumor protein, translationally-controlle 451
411125 AA151647 Hs 68877 cytxhrome b-245, alpha polypeptide 451
449267 AI638640 Hs 220624 ESTs 451
432606 NM 002104 Hs 3066 granzyme K (serine protease, granzyme 3 450
432706 NM.013230 Hs 286124 CD24 antigen (small cell lung carcinoma 450
436823 AW749865 Hs 117077 ESTε, Weakly similar to I38022 hypotheti 450
437469 AW753112 Hs 15514 hypothetical protein MGC3260 450
413703 BE158360 gb PM1-HT0383-131299 001-h08 HT0383 Homo 450
415526 N76536 Hs 265591 ESTs, Weakly similar to ALULHUMAN ALU S 450
406623 X69392 Hs 91379 πbosomal protein L26 449
456642 AW451623 Hs 109752 putative c-Myc-responsive 447
406653 AA574074 Hs 77961 major histxompatibility complex, class 447
408307 AI761786 Hs 204674 ESTs 446
428297 AA236291 Hs 183583 seπne (or cysteine) proteinaεe inhibito 446
447296 AW243614 Hs 18063 Homo εapienε cDNA FU10768 fiε, clone NT 445
416801 X98834 Hs 79971 εal (Drosophila) like 2 445
406870 AA075144 gb zm86f06 s1 Stratagene ovanan cancer 445
446291 BE397753 Hs 14623 interferon, gamma-mducible protein 30 444
416297 AA157634 Hs 79172 solute earner family 25 (mitochondria! 444
428773 BE256238 Hs 193163 bridging integrator 1 443
427640 AF058293 Hs 180015 D-dopxhrome tautomerase 443
437223 C15105 Hs 330716 Homo sapiens cDNA FU14368 fis, clone HE 443
412265 AA101325 Hs 86154 hypothetical protein FLJ12457 443
442232 AI357813 Hs 337460 ESTs, Weakly similar to A47582 B-cell gr 442
441612 AI802629 Hs 113660 Homo sapiens cDNA FLJ11631 fis, clone HE 441
424868 AI568170 Hs 96886 ESTs 441
408380 AF123050 Hs 44532 diubiquitm 440
411960 R77776 Hs 18103 ESTs 440
428782 X12830 Hs 193400 interleukin 6 rxeptor 440
408360 AI806090 Hs 44344 hypothetical protein FLJ20534 440
456629 AW891965 histone dexetylase 3 440
414416 AW409985 Hs 76084 hypothetical protein MGC2721 440
422499 AI268666 Hs 19631 ESTs, Weakly similar to I38022 hypotheti 439
414219 W20010 Hs 75823 ALL1 -fused gene from chromoεome 1q 439
427779 AA906997 Hs 180780 TERA protein 438
422340 AW296219 Hs 115325 RAB7, member RAS oncogene family-like 1 437
413276 Z24725 Hs 75260 mitogen inducible 2 436
452651 AI218918 Hs 30209 KIAA0854 protein 435
453467 AI535997 Hs 30089 ESTε 435
435961 BE293127 Hs 283722 GTT1 protein 435
415691 AW963979 Hs 24723 ESTε 434
435968 AW161481 Hs 111577 integral membrane protein 3 434
420099 D80011 Hs 95140 KIAA0189 gene product 433
421522 R48881 Hs 102991 hypothetical protein FLJ13956 433
457073 AA233210 Hs 179943 nbosomal protein L11 431
427337 Z46223 Hs 176663 Fc fragment of IgG, low affinity lllb, r 431
420732 AA789133 Hs 63525 ESTs 430
432731 R31178 Hs 287820 fibronxtiπ 1 430
437275 AW976035 Hs 292396 ESTs, Weakly similar to A47582 B-cell gr 430
408784 AW971350 Hs 63386 ESTs 430
441962 AW972542 Hs 289008 Homo sapienε cDNA FLJ21814 fiε, clone H 430
419926 AW900992 Hs 93796 DKFZP586D2223 protein 430
429058 AF138863 Hs 35254 hypothetical protein FLB6421 430
434963 AW974957 Hs 288719 Homo εapieπε cDNA FLJ12142 fis, clone MA 430
413677 AW503116 Hs 301819 zinc finger protein 146 429
428970 BE276891 Hs 194691 retinoic acid induced 3 428
408896 AI610447 Hs 48778 niban protein 426
433550 AA989061 Hs 177376 ESTs 426 406230 Target Exon 425
435655 AW105663 Hs 6947 HSPC069 protein 425
448717 R67419 Hs 21851 Homo sapiens cDNA FLJ 12900 fis, clone NT 424
437386 W52452 nbosomal protein L10 424
416759 AK000978 Hs 79741 hypothetical protein FLJ10116 423
447341 AF106941 Hs 18142 arrestin, beta 2 422
410423 AW402432 Hs 63489 protein tyrosine phosphatase, non rxept 422
409453 A1885516 Hs 95612 ESTs 422
428453 AB011110 Hs 184367 GTPase activating protein like 422
444681 AJ243937 Hs 288316 chromosome 6 open reading frame 9 4 21
416072 AL110370 Hs 79000 growth assxiated protein 43 420
450937 R49131 Hs 26267 ATP-dependant interferon response protei 420
447595 AW379130 Hε 18953 phosphodiesterase 9A 420
418452 BE379749 Hε 85201 C-type (calcium dependent, carbohydrate- 420
430594 AK000790 Hε 246885 hypothetical protein FLJ20783 420
425259 AL049280 Hs 155397 Homo sapiens mRNA cDNA DKFZp564K143 (fr 420
431560 BE244135 Hs 260238 hypothetical protein FLJ10842 420
439403 BE265745 ESTs, Weakly similar to ALUC.HUMAN mi 420
409245 AA361037 tRNA isopentenylpyrophoεphate tranεferas 418
437296 AA350994 Hs 20281 KIAA1700 417
406877 AA226392 Hs 179943 nbosomal protein L11 417
419652 AL157485 Hs 91973 hypothetical protein 415
406661 X66975 Hs 172550 polypyπmid e tract binding protein (he 415
452432 AW206008 Hs 283378 Homo sapiens cDNA FLJ21778 fis, clone H 414
448782 AL050295 KIAA0758 protein 414
407110 AA018042 Hs 252085 Prader-Willi/Angelmaπ syndrome-5 414
422960 AW890487 cadhenn 13 H-oadheπn (heart) 413
432841 M93425 Hs 62 protein tyrosine phosphatase, non rxept 412
415857 AA866115 Hε 127797 Homo sapiens cDNA FLJ11381 fis, clone HE 411
420298 AI199510 Hs 267912 ESTs, Weakly similar to ALU7.HUMAN ALU S 411
419726 U50330 Hε 1274 bone morphogenetic protein 1 411
426075 AW513691 Hs 270149 ESTs, Weakly similar to 2109260A B cell 410
430255 AK000703 Hs 323822 Homo sapiens mRNA for KIAA1551 protein 410
418699 BE539639 Hs 173030 ESTs, Weakly similar to ALU8_HUMAN ALU S 410
443035 Z45822 Hs 8906 Homo εapiens clone 24889 mRNA sequence 410
457415 AK000010 Hs 258798 hypothetical protein FLJ20003 410
412220 BE350058 Hs 36787 chromodomain helicase DNA binding protei 410
427509 M62505 Hs 2161 complement component 5 rxeptor 1 (C5a I 410
444633 AF111713 Hs 286218 junctioπal adhesion molxule 1 410
441384 AA447849 Hs 288660 Homo sapiens cDNA FLJ22182 fis, clone H 409
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (plxenta 409
422310 AA316622 Hε 98370 cytxhrome P450, subfamily IIS, polypept 408
439815 AA206079 Hε 6693 hypothetical protein FLJ20420 407
417930 H81136 Hε 334604 Homo sapiens mRNA for KIAA1870 protein, 406
418458 AA332941 Hε 85226 lipase A, lysosomal xid, cholesterol es 406
424464 R68537 Hs 17962 ESTε 406
417035 AA192455 Hs 22968 Homo εapiens clone IMAGE 451939, mRNA εe 406
412627 BE391959 Hs 74276 chloride intracellular channel 1 406
414890 BE281095 Hs 77573 undine phosphorylase 405
452248 AA093668 Hs 28578 musclebl d (Drosophιla)-lιke 405
450887 AA011518 Hs 271778 ESTs, Weakly similar to I38022 hypotheti 405
444224 AV648599 Hs 199438 ESTs 405
451351 AW058261 Hs 321435 ESTs, Weakly similar to ALU1.HUMAN ALU S 404
407792 A1077715 Hs 39384 putative sxreted ligand homologous to f 404
439864 AI720078 Hs 291997 ESTs, Weakly similar to A47582 B-cell gr 404
408745 AW936356 Hs 300925 ESTs, Weakly similar to A46010 X-lmked 403
409132 AJ224538 Hs 50732 protein kinase, AMP-xtivated, beta 2 no 401
410597 W16518 Hs 279518 amyloid beta (A4) precursor-like protein 401
409485 S80990 Hs 252136 ficolin (collagen/fibnnogeπ domam-coπt 401
426398 BE256390 Hs 169718 calponiπ 2 401
417777 AI823763 Hs 7055 ESTs, Weakly similar to I78885 senne/th 401
446979 AI654443 Hs 197683 ESTε 400
416000 R82342 Hs 79856 ESTε, Weakly similar to S65657 alpha-1 C- 400
426647 AA243464 Hs 294101 pre-B-cell leukemia transcription fxtor 400
436394 AA531187 Hs 126705 ESTs 400
409956 AW103364 Hs 727 inhibin, beta A (xtivm A, xtivm AB a 400
414602 AW630088 Hε 76550 Homo sapiens mRNA, cDNA DKFZp564B1264 (f 400
446013 AI360167 Hs 152774 ESTs 400
452404 AW450675 Hs 212709 ESTs 400
444736 AA533491 Hs 23317 hypothetical protein FLJ14681 400
438590 AA811465 Hs 123375 ESTs 400
451838 AW005866 Hs 193969 ESTs 400
449832 AA694264 Hs 60049 ESTs 400
TABLE 55B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT Number Accession 413787 7612.1 BC003047 S80794 NM.003405 X78138 AY007132 L08439 AW340648 AW131665 AI082748 AI470204 BI711078 BF350700 BI496963 AI087141 AA720684 AA862331 AA605146 BM313650 AI089749 AI359738 N69107 AW995424 AI086917 AI083995 AW340217 N99662 AI829449 AI089839 A1608761 AI342365 AI199076 AA908944 AI248943 AU160053 AI191245 A1218477 AI077943 AA864930 AI310394 AA872478 AI279782 W61343 AA565955 W46596 AA126874 AA223241 AA491574 R84813 AA491520 BG055114 AI469689 BE464590 AW664539 H67097 AL534332 C21397 AI085941 AW028427 BG939820 AI697089 AI039008 AM 25315 AI655561 AW150042 L20422 X57345 BI458375 AU142852 BI666601 BE888276 AU119302 BI603754 BG705953 BI598754 BE296713 BG002538 BF951911 N29226 BE909424 AV698274 AV683116 AV708195 AA127798 AI124697 D54224 F08031 AA340253 BF923383 BM467808 BI546644 BG777200 BG705941 BG468577 AU127209 AW403970 BI597630 BI458091 AV689560 B1669267 BG506219 BI837163 BI667275 AA343750 BE783112 BF671405 BF954720 H67636 H69456 AA484894 BI869271 BF998207 N31547 BF945817 BF947918 N90630 BG980194 AA156681 BI493502 AW273118 AI473820 AA608688 AI359337 AV712091 AA084101 BF592036 H13301 AI864305 AA505883 AI423963 AW084401 AI917740 R69858 AA033631 N79982 BE885276 AI635674 AA096126 AA700018 AV707753 A1082545 AU145681 AA629032 AI421367 AA740589 AA150830 AI248541 AA988608 AA150478 W65437 BM310234 AA262704 T28031 AI811116 BM272753 H21979 T15405 AA938406 F04963 AI188296 AW152629 AA905196 BG223058 AI831016 AI766457 AI811102 AA776573 AI922133 AA775958 AI261476 AA219489 AI688035 AI872093 BE537084AW189078 D82630 AI123121 AL583492 BE350791 R69901 W65436 BE155392 BI089081 BE155394 AL120538 AW166100 AI359620 AI174338 N20527 W47413 AA155615 AI272249 H25293 BE614558 H69864 AW383484 H78021 H11617 R56892 H23204 N21530 R82499 AW383522 AA774536 AL534331 W94127 W46459 AI866231 AA513281 AA192465 H69844 W85827 AW383642 AW383529 AA171496 AL537424 BE814866 BF823254 R82553 AI809817 AI559406
412636 1438 1 M77830 NM_004415 AF139065 BG681115 BG740377 BI712964 BG000656 AA128470 BI438324 H27408 BE931630 BE167165 AW370827 AW370813 J05211 BG698865 BG740734 BG680618 BG739778 BI765807 BM353403 BM353248 AW177784 AW205789 AW951576 AW848592 BE182164 BF149266 BE940187 BI060445 BI060444 BF350983 BE720095 BE720069 BE715154 BE082584 BE082576 BE004047 AA857316 BI039774 BE713818 BE713548 AW170253 BE160433 BI039775 AW886475 BM462504 BE931734 BF149264 AA340777 BF381183 BG621737 AU127260 AW364859 BF993352 BG223489 BE819009 BF381184 BE715956 R58704 AA852212 AW366566 BI090358 BF087707 BE819046 BE819005 AA377127 BE073467 BE819069 BE819048 BI036306 BG990973 BI040954 BF919911 AU140155 AI951766 AI434518 AW804674 BF752969 BE837009 BE925826 BF149265 AW995615 BE814264 BI039782 AU 140407 BE144243 BE709863 BF985642 BE001923 BF933510 AW265328 BG436319 BE182166 AW365175 AW847688 BE818280 AW177933 BF873679 AW178000 BE082526 BF476866 BF086994 BF592276 BE082507 BE082514 BE082505 BF873693 AW068840 AW847678 BF804153 AW365157 BE813930 BE002030 AW365153 BE184941 BF749421 BE184920 BF839562 BE184933 BF842254 BE698470 BE931048 BF999889 BF368816 BE184924 BE159646 BE714632 BE184948 BG986845 AA131128 AA099891 W39488 C04715 BF096124 BE865341 AW799304 AL603116 BE149760 BE705967 BE705966 BE705968 AW848723 AW376699 AW376817 AW376697 BG005097 BF751115 BE696084 AW848371 AW376782 AW848789 AW849074 AW361413 BF927725 BF094211 AW997139 BE865474 BE185187 BE156621 BE715089 BE713297 BE713298 BE179915 AW799309 BF872345 BF088676 BE705939 AW752599 BG005197 BF350086 BE715196 BE715155 BF752396 BF093817 BF831190 BF752409 BE006561 BG959922 BF094833 BF094748 BF094583 AW377699 AW607238 BE082519 AW377700 BF349467 AI190590 AI554403 AI392926 AU158477 BI467252 AU159919 AI760816 BF082516 AI439101 AA451923 AI340326 AI590975 BI791553 AI700963 AI142882 AA039975 AA946936 AA644381 BM314884 AA702424 AI417612 AW190555 AI220573 AI304772 AI270345 AI627383 AA552300 AI911702 AW166807 AI346078 W95070 AA149191 AA026864 AI830049 AW780435 AI078449 AI819984 AI858282 BI468588 AI860584 AI025932 AA026047 AA703232 AA658154 AA515500 AW192085 AA918281 T77861 AI927207 AI205263 BF082491 AW021347 AI568096 BE939862 AA088866 D12062 AA056527 AA782109 W19287 W02156 AW150038 AA022701 T87181 H44405 AI910434 BF082513 AI494069 AI270027 AI635878 AA128330 BG681425 BE706078 R20904 BG680059 BG676647 BF764409 AA026654 AV745530 BI762796 BG287391 AW798780 BE706045 BE926470 AW799118 BF087996 BE002273 AW879451 AI571075 BE067786 AV721320 AI022862 N29754 C03378 N84767 AA131077 H30146 BE714290 AI686869 AI568892 AI915596 AW105614 AI887258 AI538577 BE926474 BE067737 BG319486 AA247685 AW798883 AW103521 BF989173 AW860878 BE939707 BE185750 BE714064 BE713903 BE713868 BE713763 BG950164 BE713810 AW365151 BG955489 BE005272 BF915937 AW365148 AI905927 BF992780 AW853812 BG954443 BI770853 BG679406 BG740832 BG681087 BG698430 AA455100T87267 BE696209 BE696210 BI089483 BE006273 BE872225 AW391912 BE925515 BG677012 BG741970 AA026480 BE705999 BG677157 BE009090 BG681378 BE712291 BG961498 BG678984 BI040941 AA337270 AW384371 AW847442 BI058659 BE813665 W95048 W25458 AW177786 AA025851 BE931733 BF154837 BG949393 BE714441 AW996245 BE711801 AI284090 BE064323 BE719390 BE940148 BG991212 BF375714 BF349522 BG996267 T48793 BI013292 BE001925 AW365156 AW365154 AW606653 BF763109 BE931637 BE167181 BE713879 BF354008 BF678726 H90899 AW365145 W38382 AI498487
426295 510.1 BE880923 BG390191 AW470082 AW014585AI423255 BI714731 BG054894AW780248 N31683 AW664132 AW467353 AI983152AA617918 BF447795 AI088357 AA807328 AA576970 AI741153 AI755003 AI474016 AI422030 AI348114 AW997085 BM271753 AI363147 BM311311 AI146640 AI246771 AW512619 AI359020 BG054897 AI292234 AI215830 AI283836 C06205 AW503423 AW272680 N33205 AW873021 AA070724 AI753886 AW192487 AI087151 AA658909 AI346368 AI335677 AA825442 AW440066 AW131357 AW513210 AI082314 AI085455 BE551404 AA780704 AW008596 AI796964 AA917471 AI400531 AA668626 N72207 AI306482 AW440562 AI084687 AA347280 AA063536 BF477389 AI241662 AA931543 AA484310 AA812486 AI032216 AA665779 AI916336 AI350590 BF198106 AI433377 AI300638 AI672626 AI282741 AI351487 AW105544 AA973627 AW517914AA715424 AA508454 BF334080 AI274618AW367201 AW572619 AW469088 AA382095AI368364AI146934 AI357180 AI361181 BI911347 BI871044 AA136325 BF084010 BF084007 AA335788 AI920878 AA809614 BE932941 AI678261 C75308 AI148479 BE178174 W88513 BM013627
425996 138046.1 BM006551 AA367152 AW953705 AI631833 AW237429 AW027804 AA729038 BE503409 AI521935 BF739953 AA702982 AA557633 AA780065 AI218139 AW194264 D20120 AI082715 AI969980 BE857686 BE326711 AW953706 AI393749 AI383821 W67199 AI431759 AI796526 AI521794 AI796380 AW117545 AI749657 AI537634 N50122 429978 35194.2 BE738425 BE738323 BM126944 AW629678 AW265195 AI916735 AI394255 AI573090 AI354442 AW612857 AI339558 AI919424 AI377532 AI354441 AI308821 AA772275 AW055215 AI589705 AI336532 AA806547 AV682125 H93575 AW071172 AW769904 AI863985 AW265018 AW196655 D79662 BE042393 N75017 AW014741 C75509 BE748621 H92431 AW079261 AW901780 AA329482AW960115 BI260621 AI767525 R31663 BI918664 AW963196 C06195 AI678018
450377 12109.1 AB033091 AL520743 BE811813 N53332 N99716 AL561910 AA280655 BE710392 AV705100 AW293978 AW444556 AA281459 AI679751 AI873695 BG700891 BI553517 R80518 BG779771 BG534451 AA479402 AW961580 BF061430 AI857643 AI768486 AW512118 AA479302 AW770384 AW072470 AI041596 AI049699 AW592865 AA976261 BE879747 BG114119 AW183811 AA909938 BF571621 BF350794 BF351375 BE925699 AL050294 BC010371 BF982270 AL042656 BF095732 AW812618 BF095731 BG212397 BF678765 BI038602 BG388664 AW675337 BG289398 BE939598 AW805570 AA527097 AW150540 AI693720 AA743364 AI915793 N48185 AI573107 AA043474 AI351615 AI969490 AI910763 R50866 AI699181 N73808 H08164 444060 6315.1 AK055070 AK055612 AK000174 BG619806 BG108086 AI741949 AI004176 BF891936 BF378565 AW197163 BE856860 BE245124 AW674411 AA490531 AW674981 AA740788 AW274758 BF512523 AI521278 AA548759 AI802431 AW051682 AI628247 A1799606 AW088103 AA236549 AI191529 AW273168 AI168451 AW073812AW090611 AW003593 AI215845AI799616 AW474940 AA954927 BM193740 AW662704AW090127 AA969444 AI080438 AA552500 AW237538 AA481060 AI246378 AA565227 AA398921 AA207051 AA721378 BF438608 AI086295 AI886630 AA904112 AI864588 AW271985 AW078868 AA725342 BF326598 AA843572 AI082536 AA766664 AI453279 AA435673 AI619515 AA879080 AA234592 AA890223 AA766824 BI259822 AA393631 AW968840 BE940639 T83865 BE762742 AW897470 W05809 N41323 T87376 R68544 H88711 BI087136
450139 34017.1 AK001838 AU135179 AU134241 AV651702 AV650032 AV651304 AV650101 AV651263 AV651888 AV651866 AA628554 AV651355 AV651174 AV651172 AW856145 AU117599 AU135386 BG254665 AA166919 BG483981 AW809606 BG494194 AA622811 AI676156 AA687804 AI701729 AU133725AW961387 AU144387 AU151757 AA551031 BE675412 N34769 AA713483A1890079 AI588918 AI361889 AI209020 AA668981 A1240990 AA741144 AA490899 AI200221 AW589574 W96201 BG154182 AV655159 AA328145 N36348 AI081357 N76715 AA693346 AA742488 AI269719 AA897483 AI886459 AU155873 H04255 AW243986 AA557749 AI286227 R68691 R33453 AW388097
434280 1474904.1 BE005398 AA628622 AA994155 410143 MH1244 8 AK000357 AI571830 AA579613 AA668790 BF939495 BF196886 AI990982 BF591561 AI809189 AW410232 BF739769 AI144392 BF438721 AI707495 AI423359 N52503 BE855784 N94367 AI023931 AA563662 AI744624 AI221298 AI299523 AI299520 BI491312 AI452711 AI360730 AA622643 AW195955 AA470473 AW392767 AI218127 AA873430 AA906005 AA748160 H89523 AW020252 AW664988 AA970424 AA879079 AI581622 AI361357 AA468498 AW008694 AA903275 AH 87724 A1187718 AA890505 BF092771 AI066655 BE714172 BG289028 AW080390
BE001197 BF132049
419970 13569.1 AK055270 BE348291 AI190289 AW612022 AI269506 AI266578 AI269675 AW271406 BE879851 BF574163 BI497126 AW903775 BI917368
A 150900 BF244813 H79201 409208 10117.2 AK074047 AI144342 AW014280 BM145128 N28267 AW206231 AA989041 H93197 AW594063 BG236296 AW236606 AW081031 AA765843
BM144372 AA989341 AI824838 AI963970 AI637671 AW196330 BG427526 BM148789 BF893644 BF881946
430068 1177709 -2 AA947566
444207 9172.3 BE739425 AA514221 AA865491 AI828293 AA470456 AI276739 AA169357 BE932464 AA514889 AW819039 AW819083 BE843048 AI432496
AI470335 AI247243 BG533994 AA513783 AI887309 AA528036 AW972006 AW873028 AI924914 AI818810 AW152378 AW084946 AI521413
AI669583 BE932521 AI581370 BE180238 AW089750 AW771461 AW089714 AI590949 AI819148 AA731056 BF815234 BF911506 AA235803
AA485373 AI735658 AW393133 AW073080 AI707637 BF353320 BE843111 AW819036 AW393135 BG697291 AV648670 AV654332 AV687530
BG566964 AI807430 AI676072 AA837010 AI452482 AI625817 AW241750 BE048616 AI290928 AI680714 AA485530 BE175687 AV648513
AW130312 AI000556 AA632893 BE674169 BF001208 AA948166 BE175650 AA524664 AA490345 AI244948 AA602956 AA483492 AA918178
AW802049 BG675859 AV658871 BG678060 AI565004 AW819026 BE843092 AV686437 AV723049 BG616948 AI911647 AI743490 AI091096
BE857251 AI962074 AA040027 AW769317 AA343477 AA640112 BF876213 R82948 H26425 H82876 BE843095 BE843140 BG536641 BG617830
AA235802 BE774985 BE006682 BF342375 AA903144 BF338083 BF984258 AV657996 AI749532 BE768614 BE857252 BE932516 BE768573
AV657993 AV657777 AV752631 BE774974 T55847 BF095761 BF911511 BE710793 BE180119 BG617338 H45942 T55897 AV657718 BG563497
413497 1518002.1 BE177661 H06215 BE144709 BE144829 438962 195763.1 AI207343 BF813684 BF928775 AA828585 413840 38807.1 BC020284 AW953495 AW402677 BF890739 Z44378 AI660081 AI769242 T84954 C05886 AI224851 AI568340 AI024026 AW015010 AI032051
AA505095 AA830304 H98001 H63431 BG249610 AI284792 AA205732 AI598130 AW516813 AH 23905 AA132557 AI140199 H53399 AA928496
AI200299 AI400044 BE940512 BE940609 H28028 BF913868 AI301558 D79095 AI762695 AA311547 AI673408 AI673002 N67358 AA885913
AI288094 N67347 Z40311 T94918 AV722693 AW170339 AW975566 AA452774 AA504759 AA370643 T79706 AA721603 BF858887 BG982917
AI343373 AW236167 BE568091 BF747959 BF241262 BE940663 AI435278 R05794 AW027091 AI860259 AI268890 T94871 AW182884 N67183
AW149083 H42473 AI678254 R26706 AI419684 R24905 AW388568 AW363261 N31299 H63489 AW195475 AA452592 BE844216T91205 H64955
BF858811 AW962779 AW388295 BF857615 BF856552 BF856548 BF857611 AW866752
450944 36100.1 BG926557 AW965540 R76280 AA335645 BF370246 BE835794 AA725102 AW152576 BF055494 AI743398 BE464853 AI391675 AI453078
BE017970 AI803141 AI417070AA489486 BE835818AW050475 BE835826AI015220AW300496 AA343881 H98062 AA554989 N32774 AA012825
BF989549 AL576463 W60527 AW576215 N32300 AA450065 AW137525 AI290944 T16431 T50379 AA830657 N78847 T51070 AW505288
AI446370 AA100986 AA824552 BE835780 AA770659 BF370223 H03890 R76557
432666 1447 AA558585 AA565499 AI360576 AW204069 AA991648 AA864939 425291 298763.1 AI744949 AW062361 BF919486AW813419AW816041 AA354572 443194 19335.1 BI754027 BF696071 AI351939 BG151298 AI919334 AI401620 BI770165 W72057 T96158 T29478 AA181252 BG927793 AA714431 AA600749
AA181247 AA614756 AA081092 H52207 BG926934 BF222579 BG899001 N64245 AA953040 AI832406 AA102441 BG928081 AA993445 AA916041
AA987847 AA983329 AA737219 AA916443 AW128994 AI492560 AI761847 BC005272 NM.000900 X53331 M58549 BI758966 AL598829 BI754530
BG699770 BE439699 BE440148 AV704365 AV733652 BG212015 BG184149 BG200180 BG212690 BI761222 BG182079 AW338822 AI925631
AI423041 AW071181 A1889836 AW129112 BG925339 AI017633 AA568964 BF725590 AI004210 AI809799 BE083097 BG896220 AW997681
BF668788 BE083134 AW631281 BG193052 BG183095 BE440088 BG185728 AI499579 AA188162 AA864282 BI493352 AA155854 AA836749
AA836844 AA985478 AW082299 A1816747 AA450221 AA971294 BE327509 AI719662 BG576669 AI479382 BF824747 AI741800 BG982962
AI088473 AA916151 AW473324 BG901177 BE439998 AW023269 BE813871 AW999947 BE839108 AV707983 AA369722 AW796627 AW890608
AI341771 AA302459 BI493353 AA366332 AA371104 AA367277 AL547972 BG928011 AI678903 AI699886 AI956165 AA484893 AA643953
AW591063 BG203275 BG211093 AI334791 AA916589 AW058266 AI362370 AI143352 AA508721 AI928079 D57214 BE045265 AA541785
BG219510 BG201686 BG195572AW019904AW089242 AA953322AI686698 F27562 AA614749 D56645 F20774 F30660 F25646AW023542
AA827300 AA582214 AI701289 AA228293 AI906950 AA230156 AA384572 AW438988 AA742516 BI490938 AA731082 BF665869 BG190518
AV704158 BE439643AA910666AA155913 AA923097AA975721 AA985555 BG927032AA948389 AA451625AA916141 AL572719 AV707258
AW083733AA128053AI953789AI911993AA421798 BG429150AI915306Z30130AA126929 BG926630AA081013AA553696AA916094
BG924321 AI039722 AI954968 AI372839 AI401406 AI538215
414405 112689.1 AL047596 AA393792 AI670731 AI037957 AW874364 AI038137 N62286 AI241379 BE501096 AW090696 AI927369 AI669226 AI369437 AI371075
AW612409 AI686711 AI183289 AA477717 AI076122 AA635190 AA700984 AA781508 D81020 BF575223 AI356183 D79312 AI375558 H61111
BG283489 BE090666 BE090664 BE090662 H26545 428342 6712.1 AK056315 AI015524 AA724079 BI713619 AI377728 AW293682 AI928140 AI092404 AI085630 AA731340 BM469629 AW968804 AA425658
AA769094 BF446026 AW118719 AI332765 AW500888 AW576556 AI859571 AW499664 AW614573 AW629495 AW505314 W74704 AI356361
AI923640 AW070509 AI521500 AL042095 AA609309 AA761319 AI381489 H45700 AA761333 AW265424 AA909524 AA635311 AA649040
AI392620 Z40708 AI985564 AW263513 AA913892 AI693486 AW263502 AI806164 AW291137 BI061872 BI059498 AA134476 AW084888 AA036967
AW370823 T55263 BI002756 AA489664 BF827261 W74741 BF963166
441623 3362.1 BC022413 BE395396 BF754175 AA506621 BE706665 BE706678 AA723159 BE153169 BE706729 BE706558 BE153312 BE706706 AW371853
AW371849 BE153241 BC017410AI337912 AI090244AW090300 BE219837 AI623661 BE501576 BE501734 AI742232 AI023964 AI458424
AA975373 AI288904 AI984583 AA890325 N32562 AI358102 AW241694 AI038448 AI672071 AI018389 AA576391 AA977874 AW189392 W37448
AA612894 AI277548 H89551 AI699774 H89365 AA315805 AW579186 BC014584 BC014581 AW780125 AI672414 BE328145 AW600919 BF031306
AW172758 BE708322 AA345675 BE875779 H28241 H25318 BF540913 BG179688 BF110202 AA528775 W37573 BE041644 AW366504 BM129522
BM129822 AI122760 BE718200 AW887496 AA149420 BE706307 BE539395 BE748765 AI373653 R75904 BF979185 BF691393 BG495595
BI094458 BE706702 BG496559 BF248373 BG494800
406819 0.0 AA908472 418905 517 1 BM469076 AA533027 AI127512 A1368802 AA533141 AA700560AW576028AI610851 AI435361 BM129172 AW474544 BM128899AI814292
AW502039 AA531243 BF941858 AW502037 AA702337 AI419854 AA662755 AA934364 AI300510 AI291136 AA505263 AI144527 AI076919
AI633534 AI242473 AA938561 BG055372 AA512894 AI671356 AA962403 BF808010 AA663911 AA847056 AA513301 AA369069 AA377265
BG291206 AA402298 AA885766 AW801002 AA302290 AI305842 AW800873 AA302492 AA478427 AI817291 AW801104 AW801028 AA865744
BF155979 AI374743 AA478431 AH 59846 AI369757 AI800672 BF435788 AA255451 AI937707 AW006198 AI2803638F062434 AW801115
AI919181 F28413 W04214 AW152380 AW901567 AW901570 AA886371 AA384251 AI302846 BE701902 AA931606 H42673 R33703 AW901556
AA009816 AW901568 AW352200 AA256558 H15928 BI087170 AW800530 AA369068 N98562 H28652 N34644 H97650 H00956 W70039 AI142831
AA009817 F37136 N70289 AA531347 R72374 H27488 R66605
442495 9287181 AI184717 AW518883 AF121173
431824 12371251 AW972842AA516061 AA630205
433162 21679051 AI742311 AI025842 AA578843
406797 00 AI432224 AW276890 AI499346 AA937014 AA653573 AI318525 AI246219 AA961591 AI270640
447197 21768051 R36075 R36167 AI366546
447832 10367951 AI628543 AI433357 AW772732
413593 29494821 AA205248 AA204737 AA130658
427486 6841591 BF510715 BE673055 BE464111 AW590620 AI637939 AA404324 AW236441 AI650952 BF056796 AA974433
406794 00 AI890243
410295 2817.1 BG402852 BG545066 AA150252 AL036760 AA452480 AI033256 W68776 W93372 N31248 AI052219 AI367635 W69374 N88610 R58194 B1524854
BI497111 BF940043 AI129268 AI359798 AI056480 AA121421 AI042150 AW449003 AI418180 AI419420 AI356058 BF832243 AI349330 AI359448
W76647 BF477170 AA099163 BF994549 AW608256AA045418 H03770AL574791 AW069455 BE302148 AW022281 AW960273 AA121268 A1336371 AI989381 AI131425 AI147483 AI311537 AW338638 AI141649 AA709414 AI187177 AA780884 AI333805 AA045312 AI623918 AI349421 W63753 W70299 AA557276 AA299007 N98212 W74064 N24823 T54892 AA054724 W73059 AI869152 N93462 N71889 AI537432 R71628 AA303089 AI498550 T60941 AV706417 AW067848 AI150677 AW338118 AI336313 AA826256 AI139518 AA662948 AA902723 AI970175 W68682 AI089380 AI148372 H99951 AW183001 AI270317 AA532767 AA044727 AA931652 R82469 AA150261 W67788 H67495 R80715 AW149812 N78914 AI862034 W61122 AW023118 W69375 T88917 T47984 N21531 R35646 AA055544 H15534 AA688295 AA090586 AA044764 BF994641 R79547 N21313 BF674610 H02874 AW975323 R16904 AA328030 AA054671 R79546 BF832310 AI249109
413703 376077.1 BG015794 BE1583578E158353 BE158358 BE158360 BE158352 BE158351 BE158355
406870 0.0 AA075144
456629 207.22 AW891965 AW604749 BE080872 R15559 BE177623 AW883520 AW945343 AI246167 T07082 AW805679 W96278 AA135796 W32615 AW995418
AW801688 BE003837 AW801621 AW385721 AW385742AW385714 AW604757 W87409 AW604738 AW385757AW580796 AW801247 BE003239 BE003183 AA847112 AW580975 AW604760 AW385727 BE164590 BE003090 AW362791 AW604759 AW866589 AW604758 N44337 AI378548 AW890438 AA077172 AI288683 AA229639 AA091945 AW945454 AA063629 AA702504 AW861938 AW894816 AW580841 AA094372 T06399 AW885686 BE244086 BE005035 AW861913 AA551773 AW858460 AW370926 AW754352 AW889695 AW384408 AI907428 BE067491 AW861939 AA248197 AW381373 AW177325 AW806879 AA935217 BE067498 BE083742 BE067470 AW894935 BE082529 AI248811 BE179917 BE002200 AW607506 AW392889 AW894560 AW381360 AI904206 AW863533 C00609 AW381372 BE082530 AW898120 BE075323 AW392799 AW601420 AI695314 BE083790 AW858568 AW945550 BE177153 AW970506 BE350419 AI906919 AW360794 AI906917 AW885979 AW794240 AW945566 AI688683 AI688694 AW009660 AW601421 AW360793 BE066524 BE083901 AW369847 AW381871 AW935435 AW664582 AW877775 AW838449 BE180466 AW858501 BE180464 AI371163 AA778231 AI174991 BE011720 AW877776 AW877800 AW877795 T19900 AW866365 AW898099 BE011715 BE167842 BE011718 BE011724 AW363639 AW878658 AW878662 AW894887 BE082356 AW389211 AW804286 AW610312 AI904717 AW610318 AW996909 AW610296 AW901923 AW880003 AI762171 AW062582 AW368713 AW062593 AW176663 AW842064 AW842089 AW842095 AI243049 AW902074 AW062592 AW176664 AW751692 BE087703 AI907439 BE009686 BE172115 BE077030 AW608556 AW835577 AI909628 BE077029 AW176241 BE077552 BE160370 BE160288 AW835656 AW606765 AW606770 AW835678 AW606758 AW606778 AI907484 BE172821 AW606768 AW999517 AW844165 BE171738AW751683AW610493 BE177484 BE177487AA090510 AW844117 BE173367 AW999878 AI124870 BE163472 AW841823 AW379762 AW893297 AI290296 BE089132 AA610287 AW176676 AW607622 BE172639 AW893232 AA329629 BE089008 BE178350 BE178214 BE063291 AW820236 AW999653 BE089486 BE173126 BE171775 BE185787 AA558280 AI174840 AW999112 BE218391 BE172734 BE178021 BE172738 BE173324 AW603494 AL036722 R38192 R60905 H53721 H41052 AL037917 R37795 AW998972 AA767189 AW044272 H50689 AA768399 AA767764 AI087888 H44202 BE222792 N90597 W81396 N90615 AI935353 BE501168 F10945 AW118215 AI970480 AI627641 AW236081 AA574090 AI627652 AI681913 AI759983 N69591 N69276 BE467722 AW392780 BE172467 H92861 AI524921 F02989 Z39328 F02705 F01414 T88678 AI215165 H87220 AW374781
437386 5541.2 BM476605 BI545004 BI834636 BG112453 BI199049 BG112759 AA149846 H97925 AA306121 AA313204 W52451 AI734997 AA931168 AA429766 N47913 AA584321 BF940241 AI083648 AI089410 AI347705 AI343661 AI186232AI889031 N98464 AI820039 AI459034 AV652512 AA622990 BE857200 AA932998 AA740573 AI826264 AA865683 AI344550 AI027349 AI056087 AA442777 AA603724 AA873347 AI056717 AI092185 AI032895 AA535689 BF806025 BF806061 BF805985 BF746099 BF746097 AI309259 AI597603 BF806066 AI090653 AI129205 AI248410 H72993 AW615341 BF805990 BF805982 AA993819 T34373 T35604 H56242 AA648145 T35907 BF808691 N94015 AV703438 BG774276 H82341 R76371
439403 4937 10 AK056692 AF086220 AI375066 AA284293 W32566 AW797961 AA960897 AA504145
409245 3199 2 AF030234 BC017465 BG008526 AW505550 BM460141 N47324 AA361037 AA321632 N45606 AV752798 AV657116 AA296632 AU137857 AW467027 AI742080 AI624350 H58206 AA478518 AW439997 AW393555 AW393523 AI559753 AI808732 R66856 H01374 BI257369 BI259830 AW960845 BM466252 AW956813 BE768647 AV658853 BM055248 BF372070 BF372055 BF372061 AA347852 AA905863 BG505078 AV654024 BF093291 AW021929 H22650 AA459715 BG496341 BE697763 BI254209 BG499543 H42946 BI059780 BI086741 H87896 H87599 BF691752 BE768511 BG940948 W37195 BF372041 BE883796 BF372082 BF367329 BF909744 AW966003 AV714014 BI492868 BI495144 AA921845 AI693426 A1652147 AI435449 N47325 AI434429 AA573137 AH 83429 AI829962 AI332526 BF513937 AH 89561 AI221962 AI378034 AW118897 AW665247 AW340077 N41605 AA478519 AA463875 AI858260 AA463379 AI292305 BE045947 AA971089 AI125820 BG940947 AI080245 AA884954AI125702AI382934AA931835AI358631 AW439905 A1027833 AI399648 AI014533 AA347851 AA738261 N67374 N69081 AI768667 AA948472 A1819214 AA293133 AI186725 AA889214 AI222635 BI495143 N29605 N48812 AA769041 AI492769 D56771 AA095911 BE222062 D56772 AW372265 BM054985 D12465 BG534562 AW003511 H87486 H42880 AW190293 BF594697 BF377611 H22043 BI255749 BI492848 H16217 H21980 H22651 H88179 H87354 H44052 H25165 H44128 448782 34980.1 AB018301 AL050295 BF513128AW385080AL551708 AI352542 AI829703 AI819388 AW629019 AW073189 AW273857 AW118768 AI453845
AI452494 AA886341 AI057144 AA904647 AI423547 AW263913 AI094774 AI434419 AI039546 AI002491 AI240412 Z25099 AA995178 AW050649 AW026140AI796309AI584012 BE166666 AI767991 AI309041 AA724059 AI695284 AI245095 T63971 Z40627 BE166681 BG570071 BF921915 BI562702 BG506502 AV658066 R48378 AA121543 AI096938 AA618131 H40993 R48277 AI352281 BG540263 BG538901 N95226 AI356752 AI221152 Z28777 R16574 AW966449 AA044116 AW797518 BI010405 AA044288 AI093508 BE140169 T64039 BG433106 AW130367 AW130361 N73937 AA127680 AW044037 AI096437 AA384077 BF941499 T93764 BG003285 422960 11862.2 BF090249 AW954947 AW890487 AI305236 D60845 D60537 AA825429 W36294 AW890410 AW088235 BF740240 AA448709 AI350279 AA879119
AA319510 BE702077 BE699015 BE702046 AW901293 T99319 D81708 BF475488 D60383 D81751 BE699260
TABLE 55C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham etal (1999) Nature 402489495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
401466 6682292 Plus 28748-29023
401192 9719502 Minus 69559-70101
402474 7547175 Minus 53526-53628,55755-55920,57530-57757
402145 8018280 Plus 113086-114800
406230 4760409 Plus 71716-72515
TABLE 56A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xcesεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of semmomatous testicular cancer compared to normal adult testicular tissues
Pkey ExAccn UnigenelD Unigene Title R1
414438 AI879277 Hs 76136 thioredoxm 4730 424247 X14008 Hε 234734 lysozyme (renal amyloidosis) 4480
438091 AW373062 nuclear receptor subfamily 1 , group I, m 40 10
412948 BE243313 Hs 334851 LIM and SH3 protein 1 3490
417088 M54915 Hs 81170 pιm-1 oncogene 31 10
430542 AI557486 Hs 119122 nbosomal protein L13a 2960
412915 AW087727 Hs 74823 NM_004541 Homo sapiens NADH dehydrogenas 29 10
418174 L20688 Hs 83656 Rho GDP dissociation inhibitor (GDI) bet 28 15
406820 AI223958 Hε 108124 nbosomal protein S4, X-lmked 28 13
433800 AI034361 Hε 135150 lung type 1 cell membrane assxiated gly 28 10
406658 AI920965 Hs 77961 major histxompatibility complex, class 2785
416680 AW245540 Hε 79516 brain abundant, membrane attxhed signal 2770
446525 AW967069 Hs 211556 hypothetical protein MGC5487 2720
432359 AA076049 Hs 274415 Homo sapienε cDNA FLJ10229 fis clone HE 2630
422578 AF239666 Hs 1545 caudal type homx box transcnption fxt 2580
429978 AA249027 nbosomal protein S6 2540
418870 AF147204 Hε 89414 chemokine (C-X-C motif) rxeptor 4 (fus 2460
440207 AI371978 Hε 128326 ESTs 2450
425543 R23313 Hs 334895 nbosomal protein L10a 2430
442562 BE379584 dolichyl-diphosphooligosacchaπde-protei 24 10
444562 AA186715 Hs 336429 RIKE cDNA 9130422N19 geπe 2405
413063 AL035737 Hs 75184 chitmase 3 like 1 (cartilage glycoprote 2400
409038 T97490 Hs 50002 small inducible cytokine subfamily A (Cy 2290
420367 AA259090 Hs 257028 ESTε 2290
406856 AW515336 Hs 29797 πbosomal protein L10 2277
417139 M69043 Hε 81328 nuclear fxtor of kappa light polypeptid 2275
412636 NM 004415 desmoplakm (DPI, DPII) 2240
420676 AI434780 Hs 4248 vav 2 oncogene 22 10
440869 NM 014297 Hs 7486 protein expreεεed in thyroid 21 40
446627 AI973016 Hs 15725 hypothetical protein SBBI48 21 20
410315 AI638871 Hs 17625 Homo sapiens cDNA FLJ22524 fis, clone H 21 10
420754 W79431 Hs 346911 nbosomal protein L22 2098
435538 AB011540 Hs 4930 low density lipoprotein receptor-related 2090
440440 Z28925 Hs 7188 sema domain, immunoglobulin domain (Ig), 2080
429490 AI971131 Hε 23889 ESTs, Weakly similar to ALU7_HUMAN ALU S 2040
425769 U72513 Hs 159486 Human RPL13-2 pseudogene mRNA, complete 19 50
422714 AB018335 Hs 119387 KIAA0792 gene product 19 15
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 1900
413787 AI352558 tyrosine 3 monooxygenase/tryptophan 5-mo 1850
452874 AK001061 Hs 30925 hypothetical protein FLJ10199 1850
430255 AK000703 Hs 323822 Homo sapienε mRNA for KIAA1551 protein, 1800
432606 NM 002104 Hs 3066 granzyme K (εeπne protease, granzyme 3, 1790
448588 AI970276 Hs 156905 KIAA1676 1770
444784 D12485 Hs 11951 xtonuclxtide pyrophosphatase/phosphodi 1750
428782 X12830 Hs 193400 interleukin 6 receptor 1740
414092 Z14244 Hs 75752 cytochrome c oxidase subunit Vllb 1720
425945 AW410669 Hs 164280 solute earner family 25 (mitochondnal 17 15
420759 T11832 Hs 127797 Homo sapienε cDNA FU11381 fis, clone HE 17 10
440528 BE313555 HS 7252 KIAA1224 protein 1706
410143 AA188169 KIAA1191 protem 1705
421181 NM.005574 Hs 184585 LIM domain only 2 (rhombotin-like 1) 1690
426083 AW962712 Hs 126712 ESTs, Weakly similar to AF191020 1 E2IG5 1670
429183 AB014604 Hs 197955 KIAA0704 protein 1670
450937 R49131 Hs 26267 ATP-dependant interferon response protei 1660
449571 AW016812 Hs 200266 ESTs 1650
432730 AI066520 Hs 131358 ESTs 1620
426295 AW367283 zinc finger protein 6 (CMPX1) 16 15
439180 AI393742 Hs 199067 v-erb-b2 avian erythroblastic leukemia v 1590
420028 AB014680 Hs 8786 carbohydrate (N-xetylglucosamine-5-O) s 1580
421379 Y15221 Hs 103982 εmali inducible cytokine εubfamily B (Cy 1580
456236 AF045229 Hs 82280 regulator of G-protein signalling 10 1570
429469 M64590 Hs 27 glycine dehydrogenase (dxarboxylatmg, 1550
428928 BE409838 Hs 194657 cadhenn 1, type 1 , E-cadheπn (epitheli 1490
452322 BE566343 Hs 28988 glutaredoxm (thioltransferase) 1490
406656 M16714 Hs 89643 major histxompatibility complex, class 1485
414020 NM.002984 Hs 75703 small inducible cytokine A4 (homologous 1471
450377 AB033091 KIAA1265 protein 1470
425996 W67330 hypothetical protein AL110115 1460
430332 R51790 Hs 239483 Human clone 23933 mRNA sequence 1460
427691 AW194426 Hs 20726 ESTs 1442
429614 AI371172 Hs 211539 hypothetical protein MGC4248 1435
451106 BE382701 Hs 25960 N-MYC oncogene 1421
422241 Y00062 Hs 170121 protein tyrosine phoεphataεe, rxeptor t 14 13
436860 H12751 Hs 5327 PR01914 protein 1390
446899 NM 005397 Hs 16426 podocalyx -like 1390
450000 AI952797 Hs 10888 hypothetical protein FLJ21709 1375
408380 AF123050 Hs 44532 diubiquitin 1370
447526 AL048753 Hs 303649 εmall inducible cytokine A2 (monocyte ch 1340
427521 AW973352 ESTs 13 30
410598 AI817130 Hs 9195 Homo sapienε cDNA FLJ13698 fis, clone PL 1325
428664 AK001666 Hε 189095 similar to SALL1 (sal (Drosophila) like 1323
408822 AW500715 Hs 57079 Homo sapieπε cDNA FLJ 13267 fis, clone OV 1323
425289 AW139342 Hs 155530 interferon, gamma-mducible protein 16 1270
426552 BE297660 Hs 170328 moesin 1269 415857 AA866115 Hs 127797 Homo sapiens cDNA FLJ 11381 fis, clone HE 1255
436398 H87136 Hs 5174 nbosomal protein S17 1250
418151 AA864238 Hs 83583 actm related protein 2/3 complex, subun 12 30
453020 AL162039 Hs 31422 Homo εapiens mRNA cDNA DKFZp434M229 (fr 1230
410275 U85658 Hs 61796 transcription factor AP-2 gamma (activat 1228
414587 NM 004862 Hs 76507 LPS induced TNF-alpha fxtor 1225
425875 AU077333 Hs 160483 erythrocyte membrane protein band 7 2 (s 1225
415938 BE383507 Hs 78921 A k ase (PRKA) anchor protein 1 1220
419384 AA490866 Hs 39429 ESTs 1220
410185 BE294068 Hs 737 immediate early protein 12 15
407862 BE548267 Hε 337986 Homo sapiens cDNA FLJ 10934 fis, clone OV 1205
433793 AW975959 Hε 107513 ESTs, Moderately similar to KIAA1058 pro 1200
406743 AA911568 Hε 279860 tumor protein, traπslationally-controlle 11 90
408989 AW361666 Hε 49500 KIAA0746 protein 11 80
430268 AK000737 Hs 237480 hypothetical protein FLJ20730 11 80
447735 AA775268 Hs 6127 Homo sapiens cDNA FLJ23020 fis, clone L 11 80
410325 AB023154 Hs 62264 KIAA0937 protein 11 70
445817 NM.003642 Hs 13340 histone acetyltraπsferase 1 11 70
418299 AA279530 Hs 83968 integnn, beta 2 (antigen CD18 (p95), ly 11 61
445863 R12234 Hs 13396 Homo sapiens clone 25028 mRNA sequence 11 60
454413 AI653672 Hs 40092 PNAS 123 11 60
418460 M26315 Hs 85258 CD8 antigen, alpha polypeptide (p32) 11 40
428065 AI634046 Hs 157313 ESTs 11 40
432805 X94630 Hs 3107 CD97 antigen 11 36
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 11 35
444060 AA340277 Homo sapiens cDNA FLJ20167 fiε, clone CO 11 30
452436 BE077546 Hs 31447 ESTε, Moderately similar to A46010 X-lm 11 30
409963 AA133590 Hs 250857 calcium/calmodulm dependent protein kin 11 11
402474 NM 004079 Homo sapiens cathepsin S (CTSS 11 00
407112 AA070801 Hs 51615 ESTs, Weakly similar to ALU7.HUMAN ALU S 11 00
406786 AW161678 Hs 111334 ferπtin, light polypeptide 1095
428227 AA321649 Hs 2248 small inducible cytokine εubfamily B (Cy 1090
444656 AI277924 Hs 145199 ESTs 1090
453856 AA804789 Hs 19447 PDZ-LIM protein mystique 1085
440774 AI420611 Hs 153934 ESTs 1082
408669 AI493591 Hs 78146 platelel endothelial cell adhesion molx 1080
431639 AK000680 Hs 266175 phosphoprotein assxiated with GEMs 1080
444381 BE387335 Hs 283713 ESTs, Weakly similar to S64054 hypotheti 1080
418509 AB028624 Hs 85539 ATP synthase, H transporting, mitxhondr 1070
437374 AL359571 Hs 44054 ninem (GSK3B interxting protein) 1065
415899 X78992 Hs 78909 butyrate response fxtor 2 (EGF-responεe 1060
450719 AI096837 Hs 21349 ESTε, Weakly similar to RB8B.HUMAN RAS-R 1043
424800 AL035588 Hs 153203 MyoD family inhibitor 1040
446682 AW205632 Hs 211198 ESTs 1040
447211 AL161961 Hs 17767 KIAA1554 protein 1031
425234 AW152225 Hs 165909 ESTs, Weakly similarto I38022 hypotheti 1030
422105 AI929700 Hs 111680 endosulfine alpha 1021
417144 AA382104 Hs 81337 lect , galactoεide-bindmg, εoluble, 9 1020
422068 AI807519 Hs 104520 Homo εapienε cDNA FU13694 fiε, clone PL 1020
452651 AI218918 Hs 30209 KIAA0854 protein 10 15
418707 U97502 Hε 87497 butyrophilm, εubfamily 3, member A2 10 11
426996 AW968934 Hs 173108 Homo sapiens cDNA FLJ21897 fis, clone H 10 10
427761 AA412205 Hs 140996 ESTs 10 10
443523 AK001575 Hs 9536 hypothetical protein FLJ10713 9 90
402145 Target Exon 9 82
413686 AI469213 Hs 71404 ESTs 980
446488 AB037782 Hs 15119 KIAA1361 protein 980
449246 AW411209 Hs 23363 hypothetical protein FLJ10983 980
424321 W74048 Hs 1765 lymphxyte-spxific protein tyrosine km 980
407179 AA206465 thymosin, beta 4, X chromoεome 972
413497 BE177661 gb RC1-HTO598-O2O30O 011-h02 HT0598 Homo 970
430068 AA464964 gb zx80f10 ε1 Soareε ovary tumor NbHOT H 9 70
446795 AI797713 Hs 156471 ESTs 970
435522 N64214 Hs 9774 syπovial sarcoma translxatioπ gene on c 9 65
451864 N20370 Hs 69547 ESTs 965
419490 NM 006144 Hs 90708 granzyme A (granzyme 1 , cytotoxic T-lymp 960
419904 AA974411 Hs 18672 ESTs 960
427711 M31659 Hs 180408 solute earner family 25 (mitxhondπal 960
409208 Y00093 integπn, alpha X (antigen CD11C (p150), 952
424950 AA602917 Hs 156974 ESTε 9 50
447534 AW953935 Hs 288655 ESTε 9 50
419223 X60111 Hs 1244 CD9 antigen (p24) 941
423673 BE003054 Hs 1695 matrix metalloprotemase 12 (mxrophage 940
422960 AW890487 cadhenn 13, H-cadheπn (heart) 9 33
412025 AI827451 Hs 24143 Wiskott Aldπch syndrome protein interac 9 32
408784 AW971350 Hs 63386 ESTs 930
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 930
432409 AA806538 Hs 130732 KIAA1575 protein 930
440273 AI805392 Hs 325335 Homo sapienε cDNA FLJ23523 fiε, clone L 930
407110 AA018042 Hs 252085 Prader-Willi/Angelman εyndrome 5 9 22
408161 AW952912 Hε 300383 hypothetical protein MGC3032 9 20
434280 BE005398 gb CM1-BN0116-150400 189-h02 BN0116 Homo 9 20
434524 AA635931 Hs 249716 ESTε 9 20 450294 H42587 Hs 238730 hypothetical protein MGC10823 9 20
407254 AW129401 Hs 181165 eukaryotic translation elongation factor 910
434442 AA737415 ESTs 9 10
440268 BE270030 Hs 336959 Homo sapienε, clone IMAGE 3677185, mRNA 903
447519 U46258 Hs 339665 ESTs 9 00
433156 R59206 Hs 17519 Homo sapienε cDNA FLJ22539 fiε, clone H 898
410730 AW368860 DnaJ (Hsp40) homolog, subfamily B, membe 890
436823 AW749865 Hs 117077 ESTs Weakly similar to I38022 hypotheti 890
442806 AW294522 Hs 149991 ESTs 8 90
433271 BE621697 Hs 14317 nucleolar protein family A, member 3 (HI 889
445577 N40696 Hs 137064 cytoplasmic polyadenylation element bind 8 81
408437 AW957744 Hs 278469 lacπmal proline πch protein 880
420962 NM 005904 Hs 100602 MAD (mothers against decapentaplegic, Dr 8 80
431187 AW971146 Hs 293187 ESTs 880
421098 AI697901 Hs 192425 ESTs 870
424528 AW073971 Hs 238954 ESTs, Weakly similar to KIAA1204 protein 870
446108 AL036596 Hs 42322 A kmase (PRKA) anchor protein 2 870
401091 dxay xcelerating factor for complement 862
433412 AV653729 Hs 8185 CGI-44 protein, sulfide dehydrogenase Ii 860
438089 W05391 nuclear receptor subfamily 1 , group 1, m 860
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (placenta 8 60
452568 AA805634 Hs 300870 Homo sapienε mRNA, cDNA DKFZp547M072 (fr 859
414191 AW250089 Hs 75807 PDZ and LIM domain 1 (elfin) 856
411979 X85134 Hs 72984 retinoblastoma binding protein 5 850
414829 AA321568 Hs 77436 plxkstnn 8 50
430162 AW450843 Hs 346348 ESTε 850
448412 AI219083 Hs 42532 ESTε, Moderately similar to ALU8.HUMAN A 8 50
423753 Y11312 Hs 132463 phosphomoειtιde-3-kmase, class 2, beta 845
407833 AW955632 Hs 66666 ESTs, Weakly similar to S19560 proline r 843
416975 NM 004131 Hε 1051 granzyme B (granzyme 2, cytotoxic T-lymp 840
433208 AW002834 Hε 24095 ESTs 840
428970 BE276891 Hs 194691 retinoic xid induced 3 838
425284 AF155568 NS1-assxιated protein 1 833
437108 AA434054 Hs 80624 hypothetical protein MGC2560 833
408360 AI806090 Hs 44344 hypothetical protein FLJ20534 8 30
426827 AW067805 Hs 172665 methyleπetetrahydrofolate dehydrogenase 830
453716 AA037675 Hs 152675 ESTs 8 30
418840 AI821614 Hs 185831 ESTs 820
434649 AA738254 Hs 165390 ESTs, Highly similar to A40350 transcπp 820
449656 AA002008 Hs 188633 ESTε 820
425535 AB007937 Hs 158287 KIAA0468 gene product 8 17
409493 AA386192 Hε 193482 Homo sapiens cDNA FLJ11903 fis, clone HE 8 13
432559 AW452948 Hε 257631 ESTs 8 10
436797 AA731491 Hs 334477 hypothetical protein MGC14879 8 10
420099 D80011 Hs 95140 KIAA0189 gene product 8 01
417640 D30857 Hs 82353 protein C rxeptor, endothelial (EPCR) 800
420337 AW295840 Hs 14555 Homo sapienε cDNA FLJ21513 fis, clone C 800
434423 NM 006769 Hs 3844 LIM domain only 4 800
437886 BE264111 Hs 31314 retiπoblastoma-biπding protein 7 8 00
418522 AA605038 Hs 7149 Homo sapienε cDNA FU21950 fis, clone H 792
433655 AL036559 Hs 3463 πbosomal protein S23 789
435968 AW161481 Hs 111577 integral membrane protein 3 789
434511 R28982 Hs 18106 ESTs 788
423523 AW299828 Hs 193580 ESTs 7 86
409327 L41162 Hs 53563 collagen, type IX, alpha 3 784
411960 R77776 Hs 18103 ESTs 780
434159 AW135214 Hs 191828 ESTs 780
447500 AI381900 Hs 159212 ESTs 7 80
406699 L06505 Hs 182979 πbosomal protein L12 775
422603 BE242587 Hs 118651 hernatopoietically expressed hom∞box 7 68
426759 AI590401 Hs 21213 ESTs 766
406776 T16206 Hs 237164 ESTs, Highly εimilar to LDHH HUMAN L-LAC 7 62
422689 AW856665 gb RC3 CT0297-290100-013-d03 CT0297 Homo 760
444795 AI193356 Hs 160316 ESTε 7 60
406663 U24683 immunoglobulin heavy conεtant mu 759
442821 BE391929 Hs 8752 transmembrane prote 4 756
412347 AW970026 Hs 73818 ubiqumol-cytochrome c reductase hinge p 752
407252 AA659037 Hs 163780 ESTs 750
414405 AI362533 KIAA0306 protein 750
427395 AW298741 Hs 97861 ESTs, Moderately εimilar to 138022 hypot 750
429999 AI761902 Hs 99597 ESTε 7 50
441436 AW137772 Hs 185980 ESTs 750
447644 AW861622 Hs 108646 Homo sapiens cDNA FU14934 fis, clone PL 7 50
420943 AI718702 Hs 279930 major histxompatibility complex, class 746
447674 BE270640 Hs 19192 cyclm-dependent kinase 2 743
413420 AW410235 Hs 75348 proteasome (prosome, macropain) activato 742
422451 AA310753 Hs 42491 ESTs, Weakly similar to S65657 alpha-1 C- 741
437134 AA349944 Hs 42915 ARP2 (actin related protein 2, yeast) ho 740
408912 AB011084 Hs 48924 KIAA0512 gene product, ALEX2 740
419839 U24577 Hs 93304 phoεpholipaεe A2, group VII (platelet-ac 740
431427 AK000401 Hs 252748 : Homo sapiens cDNA FLJ20394 fis, clone KA 740
437469 AW753112 Hs 15514 hypothetical protein MGC3260 740
432598 AI341227 Hs 157106 i ESTs 7 38 447484 AA464839 Hs 292566 hypothetical protein FLJ14697 734
441612 AI802629 Hs 113660 Homo sapienε cDNA FLJ11631 fiε, clone HE 730
408067 BE244580 Hs 342307 hypothetical protein FLJ 10330 7 30
434963 AW974957 Hs 288719 Homo εapieπε cDNA FLJ12142 fis, clone MA 7 30
437103 AW139408 Hs 152940 ESTs 7 30
442495 AI184717 ESTs 7 30
445929 AI089660 Hs 323401 dpy 30 like protein 730
446013 AI360167 Hs 152774 ESTs 7 30
436075 BE090176 Hs 179902 transporter like protein 7 20
450139 AK001838 serum/glucxorticoid regulated kinase 720
423905 AW579960 Hs 135150 lung type I cell membrane associated gly 717
406819 AA908472 gb og82a10 s1 NCI_CGAP_Ov8 Homo εapienε 716
407719 AW963866 Hs 44021 Homo sapiens mRNA for FLJ00065 protein, 7 12
425593 AA278921 Hs 1908 proteoglycan 1, secretory granule 7 10
413886 AW958264 Hs 103832 similar to yeast Upf3, variant B 7 10
422616 BE300330 Hs 118725 selenophoεphate εynthetase 2 7 10
424677 U09414 zinc finger protein 137 (clone pHZ-30) 7 10
427254 AL121523 Hs 97774 ESTs 710
427307 AF117947 Hs 174795 PDZ domain-containing guanine nucleotide 710
438980 AW502384 gb UI-HF-BROp aka M2-0-UI r1 NIH_MGC_5 710
451129 BE072881 gb RC2-BT0548-200300 012-e09 BT0548 Homo 7 10
441878 AI801869 Hs 127982 ESTs 709
443247 BE614387 Hs 333893 c-Myc target JP01 7 04
412645 AW444433 Hs 136061 Homo sapiens, Similar to hypothetical pr 700
417315 AI080042 Hs 180450 nbosomal protein S24 700
429058 AF138863 Hs 35254 hypothetical protein FLB6421 7 00
429281 AA830856 Hε 29808 Homo sapiens cDNA FLJ21122 fis, clone C 700
445245 AB032973 Hs 12461 LCHN protein 7 00
414812 X72755 Hs 77367 monokine induced by gamma interferon 700
445055 BE512856 Hs 109051 SH3 domain binding glutamic xid πch pr 697
410397 AF217517 Hs 63042 DKFZp564J157 protein 6 96
418696 AW959433 Hs 326290 hypothetical protein FLJ12581 696
449924 W30681 Hs 146233 Homo sapienε cDNA FLJ22130 fis, clone H 695
418134 AA397769 Hs 86617 ESTs 690
424768 AA353895 Hs 152983 HUS1 (S pombe) chxkpomt homolog 690
443303 U67319 Hs 9216 caspaεe 7, apoptosis-related cysteine pr 690
411852 AA528140 Hs 107515 ESTs, Weakly similar to T00329 hypotheti 689
451838 AW005866 Hs 193969 ESTs 6 88
425367 BE271188 Hs 155975 protein tyrosine phosphatase, rxeptor t 687
453485 BE620712 Hs 33026 hypotheucal protein PP2447 685
401466 vesicle-aεεxiated membrane protein 4 684
457073 AA233210 Hε 179943 πboεomal protein L11 683
412093 BE242691 Hs 14947 ESTε 6 83
442492 AA528489 Hs 234518 nboεomal protein L23 683
449971 AA807346 Hs 288581 Homo εapienε cDNA FLJ14296 fiε, clone PL 683
431773 BE409442 Hs 268557 plxkstπn homology like domain, family 682
416401 N80139 Hs 268916 ESTs 680
426501 AW043782 Hs 293616 ESTs 6 80
435080 AI831760 Hs 155111 hypothetical protein FLJ14428 680
436876 AI124756 Hs 5337 isocitrate dehydrogenase 2 (NADP), mitx 680
449523 NM 000579 Hs 54443 chemokine (C-C motif) rxeptor 5 680
432666 AW204069 ESTs, Weakly similar to unnamed protein 679
424201 L33075 Hs 1742 IQ motif containing GTPase xtivatmg pr 677
425277 NM 001241 Hs 155478 cyclin T2 672
425246 AI085561 Hs 155321 serum response fxtor (c-fos serum respo 670
428728 NM 016625 Hs 191381 hypothetical protein 670
430299 W28673 Hs 106747 seπne carboxypeptidase 1 prxursor prot 670
433735 AA608955 Hs 109653 ESTs 670
430556 AW967807 Hs 13797 ESTs 669
417535 AA203569 Hs 191482 ESTs 669
418117 AI922013 Hs 83496 linker for xtivation of T cells 667
417558 AF045229 Hs 82280 regulator of G-protein signalling 10 665
424541 AW392551 Hs 180559 ESTs, Weakly similar to A56194 thromboxa 662
447341 AF106941 Hs 18142 arrestin, beta 2 661
407949 W21874 Hs 247057 ESTs, Weakly similar to 2109260A B cell 660
442460 NM 014135 Hs 8345 PRO0641 protein 660
428818 AI131291 Hs 102308 potasεium inwardly-rectifying channel, ε 659
453932 AW006303 Hs 329296 ESTε, Weakly similar to (defline not ava 657
415221 W07418 Hε 78225 annexm A1 656
450256 AA286887 Hs 24724 MFH-amplified sequenceε with leuc e-nc 654
441384 AA447849 Hs 288660 Homo εapiens cDNA FLJ22182 fis, clone H 651
421684 BE281591 Hs 106768 hypothetical protein FLJ10511 650
441224 AU076964 Hs 7753 calumenin 650
443749 R38828 Hs 143463 ESTs 650
448094 H24387 Hs 32061 ESTs, Weakly similar to I38022 hypotheti 650
416801 X98834 Hs 79971 sal (Drosophila) like 2 640
418259 AA215404 ESTs 640
421633 AF121860 Hs 106260 sorting nexm 10 640
435937 AA830893 Hs 119769 ESTs 640
445612 N94126 Hs 12969 hypothetical protein 640
451653 W18193 ESTs, Moderately similar to HERC2 [H sap 640
407136 T64896 Hs 287420 i Homo sapienε cDNA FLJ 11533 fis, clone HE 640
422693 BE300073 Hs 279860 I tumor protein, translationally-controlle 6 39 434817 AA082118 Hs 102737 goliath protein 638
414476 AA301867 Hs 76224 EGF-contaming fibulin like extrxellula 635
425410 AA310974 Hs 156828 Homo sapieπε cDNA FLJ10522 fiε, clone NT 634
431840 AA534908 Hs 2860 POU domain, class 5, transcnption facto 633
435812 AA700439 Hs 188490 ESTε 631
401113 εolute carrier family 22 (organic cation 630
408418 AW963897 Hs 44743 KIAA1435 protein 630
412220 BE350058 Hs 36787 chromodomam helicase DNA binding protei 630
426780 BE242284 Hs 172199 adeπylate cyclase 7 630
427202 BE272922 Hs 173936 interieukin 10 receptor, beta 630
434699 AA643687 Hs 149425 Homo sapiens cDNA FLJ11980 fis, clone HE 630
447887 AA114050 Hs 19949 caεpase 8, apoptosis related cysteine pr 6 30
449576 AW014631 Hs 225068 ESTs 630
444933 NM 016245 Hs 12150 retinal short chain dehydrogeπase/reduct 630
432841 M93425 Hs 62 protein tyrosine phosphatase, non rxept 627
411975 A1916058 Hε 144583 ESTs 626
452852 AK001972 Hε 30822 hypothetical protem FLJ11110 625
433162 AI025842 ESTs 623
449322 AI638616 Hε 196566 ESTε 622
430333 S70114 Hs 239489 TIA1 cytotoxic granule assxiated RNA bi 620
440327 R12581 Hs 191146 ESTs 620
442832 AW206560 Hs 253569 ESTs 620
456362 AW973003 Hs 179909 hypothetical protein FLJ22995 620
427968 AI857607 Hs 181301 cathepsin S 618
414662 AL036058 Hs 76807 major histocompatibility complex, clasε 616
418113 AI272141 Hs 83484 SRY (εex determining region Y) box 4 616
406870 AA075144 gb zm86f06 ε1 Stratagene ovarian cancer 6 15
416003 X98001 Hε 78948 Rab geranylgeranyltransferase, beta subu 615
445493 AI915771 metallothionem 1E (functional) 6 15
424687 J05070 Hs 151738 matnx metalloprotemase 9 (gelatmase B 6 14
427477 AW973119 Hs 178391 πboεomal protein L44 614
422499 AI268666 Hs 19631 ESTε, Weakly similar to I38022 hypotheti 613
443441 AW291196 Hs 92195 ESTs 612
413677 AW503116 Hs 301819 zinc finger protein 146 611
406797 AI432224 nbosomal protein L6 610
406857 AA613726 Hs 29797 πbosomal protein L10 610
410387 AI277367 Hs 47094 ESTs 610
410503 AW975746 Hs 188662 KIAA1702 protein 610
441962 AW972542 Hs 289008 Homo εapienε cDNA FU21814 fiε, clone H 610
425762 BE244076 Hs 159578 AT-hook transcnption fxtor AKNA 608
406877 AA226392 Hs 179943 πbosomal protein L11 607
407784 AW139585 Hs 12708 ESTs 605
416297 AA157634 Hs 79172 solute camerfamily 25 (mitxhondπal 605
446272 BE268912 Hs 14601 hematopoietic cell-specific Lyn subεtrat 601
412949 AI471639 Hs 71913 ESTε 600
420059 AF161486 Hs 94769 RAB23, member RAS oncogene family 600
435756 AI418466 Hs 33665 ESTε 600
451658 AW195351 Hs 250520 ESTs, Moderately similar to I38022 hypot 600
441623 AA315805 desmoglein 2 598
416926 H03109 Hs 263395 HT018 protein 596
425190 AW028302 Hs 155079 protein phosphataεe 2, regulatory εubuni 595
441244 BE612935 Hs 184052 PP1201 protein 595
421305 BE397354 Hs 324830 diptheπa toxin resistance protein requi 595
430504 H52761 Homo sapiens, clone MGC 12617, mRNA, com 594
422310 AA316622 Hε 98370 cytxhrome P450, subfamily IIS, polypept 592
408605 AF025374 Hs 46465 T-cell, immune regulator 1 591
433891 AA613792 gb no97h03 ε1 NCI CGAP Pr2 Homo sapiens 590
406542 C19000728* gι|12585552|sp|Q9Y2Q1 |Z257_HU 590
406858 A1865720 Hs 29797 πbosomal protein L10 590
408331 NM 007240 Hs 44229 dual spxificity phosphatase 12 590
432729 AK000292 Hs 130732 hypothetical protein FLJ20285 590
439451 AF086270 Hs 278554 heter hromatin-like protein 1 590
455263 AW961702 Homo sapienε cDNA FU14028 fiε, clone HE 590
441321 H17182 Hε 7771 B-cell asεxiated protein 588
429083 Y09397 Hs 227817 BCL2-related protein A1 587
406806 AW088535 πboεomal protein, large, P0 587
416987 D86957 Hs 80712 KIAA0202 protein 586
450988 BE618571 Hs429 ATP εyπthaεe, H transporting, mitxhoπdr 583
428773 BE256238 Hs 193163 bπdgmg integrator 1 583
406794 AI890243 πbosomal protein L6 582
457752 AI821270 Hs 285643 Homo sapiens cDNA FLJ14364 fis, clone HE 5 82
435511 AA683336 Hs 189046 ESTs 581
451589 AA424791 Hs 5734 meningioma expresεed antigen 5 (hyaluron 580
439979 AW600291 Hs 6823 hypothetical protein FLJ10430 580
412528 AI123478 Hs 32112 ESTε 580
424875 AI187945 Hs 199310 ESTε 580
426981 AL044675 Hs 173081 KIAA0530 protein 580
447711 AI459554 Hs 161286 ESTε 580
449961 AW265634 Hs 133100 ESTs 580
416759 AK000978 Hs 79741 hypothetical protein FLJ10116 580
415082 AA160000 Hs 137396 ESTs, Weakly similar to JC5238 galactosy 579
422773 AB028962 Hs 301552 KIAA1039 protein 578
441455 AJ271671 Hs 7854 zinc/iron regulated transporter-like 578 414774 X02419 Hs 77274 plasminogen activator, urokmase 577
449317 AW293413 Hs 132906 19A24 protein 575
425787 AA363867 Hs 155029 ESTs 573
414890 BE281095 Hs 77573 undine phosphorylase 572
426354 NM 004010 Hs 169470 dystrophin (muεcular dyεtrophy, Duchenne 571
435961 BE293127 Hs 283722 GTT1 protein 571
419378 R24922 Hs 90078 nucleotide-εugar tranεporter similar to 570
431155 AW971213 gb EST383301 MAGE resequenceε, MAGL Homo 570
437457 AA757900 Hs 270823 ESTs, Weakly similar to S65657 a!pha-1C- 570
446659 AI335361 Hs 226376 ESTε 570
457250 AA811987 Hs 125779 ESTε 570
414150 AA136026 gb zn88d07 r1 Stratageπe lung carcinoma 568
439924 AI985897 Hs 125293 ESTε 567
452472 AW957300 Hs 294142 ESTε, Weakly similar to C55663 oligodend 566
451812 X81889 Hs 152151 plakophilin 4 5 65
432588 X92715 Hs 3057 zinc finger protein 74 (Cos52) 563
440119 AA865455 Hs 125331 ESTs, Moderately similar to unknown [H s 563
424326 NM 014479 Hs 145296 ADAM like disintegnn protease, dxyεm 560
431770 BE221880 Hs 268555 5'-3' exoπbonuclease 2 560
436511 AA721252 Hs 291502 ESTs 5 60
446630 AW384793 Hs 15740 Homo sapienε mRNA, cDNA DKFZp434E033 (fr 560
406623 X69392 Hs 91379 πboεomal protein L26 560
452382 N38902 Hs 211539 hypothetical protein MGC4248 557
416047 BE439894 Hs 78991 DNA εegment, numerouε copieε, expreεεed 556
437296 AA350994 Hs 20281 KIAA1700 5 56
453985 N44545 Hε 251865 ESTε 5 56
443351 AW016783 Hs 30799 Homo εapiens cDNA FLJ13471 fis, clone PL 555
448877 AI583696 Hs 253313 ESTs 553
435748 AA699756 Hs 117335 ESTs 552
420732 AA789133 Hs 63525 ESTε 5 51
421818 AW992976 Hs 50098 NM.002489 Homo εapienε NADH dehydrogenas 5 50
430915 AA488953 gb aa55e05 r1 NCI.CGAP.GCB1 Homo sapiens 550
436716 AI433540 gb tι69g05 x1 NCI_CGAP_Kιd11 Homo sapien 550
437442 T85104 Hs 222779 ESTε, Moderately similar to similar to N 550
449625 NM.014253 odz (odd Oz/ten m, Drosophila) homolog 1 5 50
456497 AW967956 Hs 123648 ESTs, Weakly similar to AF108460 1 ubinu 550
451287 AK002158 Hs 26194 likely homolog of mouεe immuπity-aεεocia 550
433701 AW445023 Hs 15155 ESTε 549
427640 AF058293 Hs 180015 D-dopxhrome tautomeraεe 547
420552 AK000492 Hs 98806 hypothetical protein 545
449338 H73444 Hs 394 adrenomeduilin 542
427176 AW381569 Hs 40334 ESTε 542
409945 AW015935 Hs 122642 ESTε 540
421568 W85858 Hs 99804 ESTs 540
423961 D13666 Hs 136348 peπostιn(OSF-2os) 540
440719 AA150869 Hs 26267 ATP-depeπdant interferon reεponεe protei 540
443035 Z45822 Hs 8906 Homo εapienε clone 24889 mRNA εequence 540
458659 AW749895 Hs 332520 Homo εapieπε mRNA, cDNA DKFZp434A1014 (f 540
424415 NM 001975 Hs 146580 enolase 2, (gamma neuronal) 540
420137 AA306478 Hs 95327 CD3D antigen, delta polypeptide (TιT3 co 539
422163 AF027208 Hs 112360 prommin (mouse)-lιke 1 538
439815 AA206079 Hs 6693 hypothetical protein FLJ20420 537
452432 AW206008 Hs 283378 Homo sapienε cDNA FLJ21778 fis, clone H 5 37
457465 AW301344 Hs 122908 DNA replication fxtor 537
412935 BE267045 Hs 75064 tubulm-spxific chaperone c 536
409485 S80990 Hs 252136 ficolin (∞llageπ/fibnnogeπ domam-cont 535
430283 BE391688 RAB7, member RAS oncogene family 533
406814 AA642947 Hs 119122 nboεomal protein L13a 533
409019 AW385412 myoεm regulatory light chain 2, smooth 530
410561 BE540255 Hs 6994 Homo sapiens cDNA FLJ22044 fis, clone H 530
412623 R28898 Hs 74170 metallothionein 1E (functional) 5 30
417450 AA314435 Hs 17519 Homo sapiens cDNA FU22539 fis, clone H 530
418702 BE268388 Hs 86945 ESTs, Weakly similar to A46010 X-lmked 530
419926 AW900992 Hs 93796 DKFZP586D2223 protein 530
422900 AA641201 Hs 222051 ESTs 5 30
423494 AW504365 Hs 24143 Wiskott-Aldnch syndrome protein interx 5 30
427667 AK001279 Hs 180171 Homo εapienε cDNA FLJ 10417 fiε, clone NT 530
427774 AA278583 Hs 180737 Homo εapienε clone 23664 and 23905 mRNA 530
430177 AW969233 Hs 302746 MSTP028 protein 530
430835 AI240006 Hs 192326 ESTε 530
433009 AA761668 gb nz24c08 ε1 NCI.CGAP.GCB1 Homo sapiens 530
439776 AL360140 Hε 176005 Homo sapienε mRNA full length insert cDN 530
447082 T85314 Hs 54629 thioredoxin like 530
415995 NM 004573 phospholipase C, beta 2 5 29
424578 AK001973 Hs 150890 hypothetical protein 527
441303 AW293081 Hs 241801 ESTs 527
427816 AA159248 Hs 180909 peroxiredoxm 1 527
443963 AA878183 Hs 17448 Homo εapienε cDNA FLJ13618 fiε, clone PL 526
450273 AW296454 Hs 24743 hypothetical protein FLJ20171 524
444708 AW971049 Hs 11774 protein (peptidyl prolyl cis/trans isome 523
415121 D60971 Hs 34955 Homo εapieπs cDNA FLJ13485 fis, clone PL 521
458079 AI796870 Hs 54277 DNA segment on chromosome X (unique) 992 521
405086 NM.006662* Homo εapienε Snf2 related CBP 520 413401 AI361861 Hs 118659 ESTs 520
418459 R85436 Hs 268814 ESTs 520
422134 AW179019 Hs 112110 mitxhondπal nbosomal protem L42 520
426496 D31765 Hs 170114 KIAA0061 protein 520
431749 AL049263 Hs 306292 Homo sapiens mRNA cDNA DKFZp564F133 (fr 520
434372 AA631373 gb np86c01 si NCI.CGAP Thy1 Homo sapienε 520
436812 AW298067 gb UI-H-BWO ajp g 09 0-UI s1 NCI_CGAP.Su 520
441390 AI692560 Hs 131175 ESTs 520
449419 R34910 Hs 119172 ESTs 520
453127 AI696671 Hs 294110 ESTs 520
456373 BE247706 Hs 89751 membrane-spanning 4-domaιns, subfamily A 520
417750 AI267720 Hs 260523 εynovial εarcoma traπslxated to X cfiro 5 19
451814 AA847992 Hs 137003 ESTs 5 18
410423 AW402432 Hs 63489 protein tyroεme phoεphatase, non rxept 518
406799 AA908548 gb og83g12 s1 NCI.CGAP.Ov8 Homo εapienε 5 16
413963 R84282 Hs 75643 nuclear factor (erythroid deπved 2), 45 5 15
422293 X94453 Hs 114366 pyrrolιne-5-carboxylate synthetase (glut 5 14
432465 D56165 Hs 275163 noπ-metastatιc cellε 2 protein (NM23B) 5 12
414768 AW376989 Hs 259855 elongation factor-2 kinase 5 12
447232 AW499834 Hs 327 interieukin 10 receptor, alpha 512
430478 NM.014349 Hs 241535 apolipoprotein L, 3 511
420151 AA255931 Hs 186704 ESTs 5 11
434274 AA628539 Hs 116252 ESTs, Moderately similar to ALU1.HUMAN A 5 10
419317 AA236282 Hs 172318 ESTs 510
424699 AW206227 Hs 287727 hypothetical protein FLJ23132 5 10
428403 AI393048 Hs 326159 leucine rich repeat (in FLU) interxtm 5 10
430968 AW972830 gb EST384925 MAGE resequences, MAGL Homo 5 10
431709 AF220185 Hs 267923 uncharacteπzed hypothalamus protein HT0 5 10
436137 AI056769 Hs 133512 ESTs 5 10
440948 AW188311 Hs 128619 ESTs 5 10
448497 BE613269 Hs 21893 hypothetical protein DKFZp761 N0624 509
416655 AW968613 Hs 79428 BCL2/adenovιrus E1B 19kD interacting pro 509
417228 AL134324 Hs 7312 ESTε 509
424868 AI568170 Hs 96886 ESTs 508
418905 BE539674 xtinin, alpha 4 508
427726 AI359144 Hs 143688 Homo sapienε cDNA FLJ23031 fis, clone L 507
442618 R56222 Hs 26514 ESTs 506
445715 AB012958 Hs 13137 UV radiation resistance assxiated gene 506
406813 AW276131 πbosomal protein L13a 506
454128 AL031259 Hs 41639 programmed cell death 2 505
440709 AW797724 Hs 130350 ESTs 505
436372 AW972301 Hs 310286 ESTs 505
446173 BE565849 Hs 14158 copine III 505
453330 AI268081 Hs 342389 peptidylprolyl Isomerase A (cyclophilm 504
418876 AA740616 gb ny97f11 s1 NCI.CGAP.GCB1 Homo sapiens 503
408405 AK001332 Hs 44672 hypothetical protein FLJ 10470 500
410570 AI133096 Hs 64593 ATP synthase, H transporting, mitxhondr 500
410800 BE280421 Hs 94499 ESTs 500
431451 AA761378 Hs 192013 ESTs 500
432879 AW815932 Hs 173734 ESTs, Weakly similar to ALU1.HUMAN ALU S 500
435655 AW105663 Hε 6947 HSPC069 protein 500
435919 AI052189 Hε 114104 ESTs 500
436394 AA531187 Hs 126705 ESTs 500
438459 T49300 Hs 35304 Homo sapienε cDNA FLJ13655 fis, clone PL 500
442232 AI357813 Hs 337460 ESTs, Weakly similar to A47582 B-cell gr 500
442685 AB033017 Hs 8594 KIAA1191 protein 500
444454 BE018316 Hs 11183 sorting nexm 2 500
444670 H58373 Hε 332938 hypothetical protein MGC5370 500
447197 R36075 gb yh88b01 s1 Soares plxenta Nb2HP Homo 500
450113 AI683098 Hs 200866 ESTs, Moderately similar to ALU7.HUMAN A 500
450511 R07423 Hs 85092 thyroid hormone receptor mterxtor 11 500
450887 AA011518 Hs 271778 ESTε, Weakly εimilar to I38022 hypotheti 500
452056 AW955065 Hs 101150 Homo εapiens, clone IMAGE 4054156, mRNA, 500
457068 X69391 πbosomal protein L6 500
406793 AW264291 Hs 5662 guanine nucleotide binding protein (G pr 497
439864 AI720078 Hs 291997 ESTs, Weakly similar to A47582 B-cell gr 495
420298 AI199510 Hs 267912 ESTs, Weakly similar to ALU7JHUMAN ALU S 494
440638 AI376551 gb te64e10 x1 Soares_NFL_T_GBC_S1 Homo s 492
400281 Eos Control 491
414420 AA043424 Hs 76095 immediate early response 3 490
415799 AA653718 Hs 225841 DKFZP434D193 protein 490
434666 AF151103 Hs 112259 T cell rxeptor gamma locus 490
449057 AB037784 Hs 22941 KIAA1363 protein 490
448625 AW970786 Hs 178470 hypothetical protein FLJ22662 490
451598 N29102 Hs 118078 ESTε 490
409686 AK000002 Hs 55879 Homo εapieπε mRNA, cDNA DKFZp434L0827 (f 488
410597 W16518 Hs 279518 amyloid beta (A4) precursor-like protein 488
446291 BE397753 Hs 14623 interferon, gamma-mducible protein 30 486
447150 AI439011 Hs 86386 myeloid cell leukemia sequence 1 (BCL2-r 486
418458 AA332941 Hs 85226 lipase A, lysosomal xid, cholesterol es 485
422627 BE336857 Hs 118787 tranεforming growth factor, beta-induced 485
437186 AA338305 Hs 5472 hypothetical protein FLJ20173 484
415825 Y18024 Hs 78877 moεitol 1 ,4,5-trιεphoεphate 3-kιnase B 484 406781 AA639388 gb nq88b06 s1 NCI_CGAP_Co9 Homo sapiens 483
449810 AB008681 Hs 23994 activin A rxeptor, type IIB 4 82
410323 AI241708 Hs 296322 Homo sapiens cDNA FLJ22844 fis, clone K 481
444652 BE513613 Hs 11538 actm related protein 2/3 complex, subun 481
422340 AW296219 Hs 115325 RAB7, member RAS oncogene family like 1 481
400424 AJ276316 Hs 287374 zinc finger protein 304 480
411573 AB029000 Hs 70823 KIAA1077 protein 4 80
421045 BE144608 Hs 55533 ESTs 480
425235 AA353113 Hs 112497 Homo sapiens cDNA FLJ22743 fis, clone H 480
430387 AW372884 Hs 240770 nuclear cap binding protein subunit 2, 2 480
438590 AA811465 Hs 123375 ESTs 480
442071 BE048433 Hε 276043 ESTs 480
449567 AI990790 Hs 188614 ESTs 480
453213 AA082650 Hs 6217 Homo sapiens cDNA FLJ 12521 fis, clone NT 480
440129 AA865818 ESTε, Weakly similar to S71886 Ste20-lιk 478
437802 AI475995 Hs 122910 ESTs 477
409461 AA382169 Hs 54483 N myc (and STAT) mterxtor 477
421932 W51778 Hs 323949 kangai 1 (suppresεion of tumoπgemcity 474
428453 AB011110 Hs 184367 GTPase activating protein like 474
413441 AI929374 Hs 75367 Src like-adapter 474
446560 AK001567 Hs 311002 Homo sapiens cDNA FLJ10705 fis, clone NT 473
435541 AA687361 Hs 221318 ESTs 471
410557 AA085803 Hs 192997 ESTs Moderately similar to 178885 seππ 470
412766 BE544475 Hs 54347 ESTs 470
415526 N76536 Hs 265591 ESTs, Weakly similar to ALU1 HUMAN ALU S 470
418973 AA233056 Hs 191518 ESTs 470
421433 AI829192 Hε 22380 ESTs 470
432925 AA878324 Hs 264750 ESTs 470
438869 AF075009 gb Homo sapiens full length insert cDNA 470
442233 AW967149 Hs 28439 ESTs, Weakly similar to I38022 hypotheti 470
447198 D61523 Hs 283435 ESTs 470
448552 AW973653 Hs 20104 hypothetical protein FLJ00052 470
444681 AJ243937 Hs 288316 chromosome 6 open reading frame 9 466
414598 AI094221 Hs 135150 lung type I cell membrane-aεεxiated gly 466
447817 BE620775 Hs 4866 Homo εapienε cDNA FLJ14387 fis, clone HE 465
416062 AA724811 Hs 334791 Homo sapienε cDNA FLJ14609 fiε, clone NT 465
406661 X66975 Hs 172550 polypyπmidme trxt binding protein (he 464
424582 AF026849 Hs 150922 BCS1 (yeast homolog) like 464
411165 NM 000169 Hs 69089 galxtosidase alpha 463
435905 AW997484 Hs 5003 KIAA0456 protein 463
445776 NM.001310 Hs 13313 cAMP responsive element binding protein 462
424730 NM.003358 Hs 23703 ESTε Moderately similar to CEGT.HUMAN C 462
414747 U30872 Hs 77204 centromere protein F (350/400kD, mitosin 462
410668 BE379794 Hs 159651 hypothetical protein 461
406774 AW518383 Hs 177592 nbosomal protein, large, P1 460
406648 AA563730 Hs 277477 major histxompatibility complex, class 460
407951 W77762 Hs 79015 antigen identified by monoclonal antibod 460
415682 AI347128 Hs 191870 ESTs 460
417621 AV654694 Hs 82316 interferon induced, hepatitis C-ass∞iat 460
419970 AW612022 ESTs 460
420012 AW957965 Hs 99014 Homo sapiens, clone IMAGE 3632168, mRNA 460
431574 AW572659 Hs 261373 hypothetical protein dJ4340143 460
432586 AA568548 ESTs 460
437438 AL359620 Hs 14217 hypothetical protein DKFZp762P2111 460
441355 AI822034 Hs 137097 ESTs 460
444539 AI955765 Hs 146907 ESTs, Weakly similar to 2004399A chromos 460
458965 AA010319 Hs 60389 ESTε 460
406655 M21533 Hs 277477 major histxompatibility complex, class 460
414915 NM.002462 Hs 76391 myxovirus (influenza) reεistance 1, homo 460
414821 M63835 Hε 77424 Fc fragment of IgG, high affinity la, re 459
423766 AA303799 Hε 300141 nbosomal protein L39 459
451351 AW058261 Hε 321435 ESTs, Weakly similar to ALULHUMAN ALU S 456
450043 AA885699 Hs 24332 CGI-26 protein 456
447742 AF113925 Hs 19405 caspase recruitment domain 4 454
433339 AF019226 Hs 8036 glioblastoma overexpressed 454
426395 BE151985 hypothetical protein FLJ23316 453
418300 AI433074 Hs 86682 Homo sapiens cDNA FU21578 fis, clone C 453
423799 AW026300 Hs 132906 19A24 protein 453
445093 AI207197 ESTs 452
428044 AA093322 Hs 301404 RNA binding motif protein 3 452
453968 AA847843 Hs 62711 High mobility group (πonhistone chromoεo 451
414194 BE175494 Hs 75811 N-xylεphingosme amidohydrolase (xid c 450
427747 AW411425 Hs 180655 seπne/threoniπe kinase 12 450
406745 AW511970 Hs 279860 tumor protein, translationally-controlle 450
407013 U35637 Hs 83870 gb Human nebulm mRNA, partial cdε 450
407198 H91679 gb yv04a07 ε1 Soareε fetal liver spleen 450
414646 AA353776 Hε 901 CD48 antigen (B-cell membrane protein) 450
429687 AI675749 Hε 211608 nucleopoπn 153kD 450
436566 BE545586 Hs 278712 Homo sapiens cDNA FLJ 11074 fis, clone PL 450
437634 AW293046 Hs 255158 ESTs 450
439971 W32474 Hs 301746 RAP2A, member of RAS oncogene family 4 50
442485 BE092285 Hs 29724 hypothetical protein FLJ13187 4 50
445873 AA250970 Hs 251946 poly(A)-bιndιng protein, cytoplasmic 1-1 450 450497 H64159 Hs 15328 ESTs 450
417497 AW402482 Hs 82212 CD53 antigen 450
447667 AL117611 Hs 19150 Homo sapiens mRNA, cDNA DKFZp564A2164 (f 449
413856 D13639 Hs 75586 cyclin D2 449
419556 U29615 Hs 91093 chitmase 1 (chitotπosidase) 449
429617 X89984 Hs 211563 B cell CLL/lymphoma 7A 448
427157 U51166 Hs 173824 thymme DNA glycosylase 448
446021 BE389213 Hs 286 πbosomal protein L4 447
413822 R08950 Hε 272044 ESTs Weakly similar to ALULHUMAN ALU S 446
412819 T25829 Hs 24048 FK506 binding protein precursor 446
448717 R67419 Hs 21851 Homo sapiens cDNA FLJ12900 fis, clone NT 445
401846 NM_000988* Homo sapienε πbosomal protei 444
422303 AW410382 Hs 27556 hypothetical protein FLJ22405 443
442358 BE567985 Hs 18585 ESTs, Moderately similar to ALU4JHUMAN A 443
436623 AI417073 Hs 107265 ESTs 442
412146 M92444 Hs 73722 APEX nuclease (multifunctional DNA repai 442
437042 AK000702 Hs 5420 hypothetical protein FLJ20695 442
416754 H07145 Hs 6799 ESTs, Weakly similar to T12483 hypotheti 441
436671 AW137159 Hs 183291 ESTs 440
410079 U94362 Hs 58589 glycogenm 2 440
420150 AA648712 Hs 29798 KIAA1712 protein 440
424723 BE409813 Hs 152337 protein arginine N methyltransferase 3(h 440
428931 AA994979 Hs 98967 ATPase, H() transporting, lysoεo al, non 440
429109 AL008637 Hs 196352 neutrophil cytosolic fxtor 4 (40kD) 440
430280 AA361258 Hs 237868 interleukin 7 rxeptor 440
438330 AW450572 Hs 257316 ESTs 440
438962 BE046594 gb hπ41c11 x1 NCI CGAP.RDF2 Homo sapiens 440
444794 AI419991 Hs 145225 ESTs 440
445100 AW188205 Hs 12311 Homo sapiens clone 23570 mRNA sequence 440
449659 R60031 Hs 198899 eukaryotic translation initiation factor 440
449832 AA694264 Hs 60049 ESTs 440
452404 AW450675 Hε 212709 ESTs 440
447296 AW243614 Hs 18063 Homo sapienε cDNA FLJ10768 fiε, clone NT 439
425097 NM 014247 PDZ domain containing guanine nucleotide 437
441607 NM 005010 Hs 7912 neuronal cell adhesion molxule 437
406742 AI468091 Hs 279860 tumor protein, translationally-controlle 435
425095 AW014160 Hs 182585 KIAA1276 protein 434
410342 R31350 Hs 743 Fc fragment of IgE, high affinity I, rec 434
442333 AI650877 Hs 129302 ESTε 433
424971 AA479005 Hs 154036 tumor suppresεmg subtransferable candid 432
415912 H08859 Hs 206469 ESTs, Weakly similar to ALU6.HUMAN ALU S 432
437386 W52452 πbosomal protein L10 431
408558 AW015759 Hs 235709 Homo sapiens mRNA, cDNA DKFZp667B0711 (f 430
408875 NM 015434 Hs 48604 DKFZP434B168 protein 430
409604 AW444448 Hs 49124 ESTs 430
418866 T65754 gb yd 1c07 s1 Stratagene lung (937210) H 430
419423 D26488 Hs 90315 KIAA0007 protein 430
422017 NM 003877 Hs 110776 STAT induced STAT ιnhιbιtor-2 430
422797 AB033064 Hs 236463 KIAA1238 protein 430
428467 AK002121 Hs 184465 hypothetical protein FLJ 11259 430
432290 AK001099 Hs 274273 Homo sapiens cDNA FU10237 fis, clone HE 430
434551 BE387162 Hs 280858 ESTε, Highly similar to A35661 DNA excis 430
436138 H53323 Hs 25717 Homo sapiens cDNA FU23454 fis, clone H 430
438915 AA280174 Hs 285681 Williams-Beuren syndrome chromosome regi 430
449217 AA278536 Hs 23262 πbonucleaεe, RNase A family, k6 430
452994 AW962597 Hs 31305 KIAA1547 protein 430
418883 BE387036 Hs 1211 xid phosphatase 5, tartrate resistant 430
437250 BE257342 Hs 94576 hypothetical protein MGC3062 429
440910 H97875 Hs 117974 ESTs 429
406853 AA614553 Hs 252259 hypothetical protein FLJ23059 428
432295 BE091049 Hs 343665 nbosomal protein S15a 428
400244 Eos Control 428
413518 BE149455 Hε 5415 beta-2-mιcrogIobulιn 428
409132 AJ224538 Hε 50732 protein kinase, AMP-xtivated, beta 2 no 427
406746 AA580395 Hs 279860 tumor protein, translationally-controlle 426
400395 AF111167 v-fos FBJ munne oεteosarcoma viral onco 426
443229 AI057129 Hs 133396 ESTs 426
450201 T97838 Hs 25722 ESTs 425
409636 AA305729 Hs 18272 ammo xid transporter system A1 425
422082 AA016188 Hs 111244 hypothetical protein 424
444099 D87432 Hs 10315 solute earner family 7 (cationic ammo 424
453902 BE502341 Hs 3402 ESTs 424
415189 L34657 Hs 78146 plateletfeπdothelial cell adhesion molx 422
404854 Target Exon 421
406653 AA574074 Hs 77961 major histxompatibility complex, class 420
400440 X83957 Hs 83870 nebulin 420
415049 N67334 Hs 50158 ESTs 420
418304 AA215702 gb zr97g10 r1 NCI.CGAP.GCB1 Homo sapienε 420
423180 AF068302 Hs 125031 cholme/ethanolammephosphotranεferase 420
424684 AW752714 Hs 5174 πboεomal protein S17 420
429412 NM 006235 Hs 2407 POU domain, claεε 2, aεsxiatmg factor 420
438141 AW946871 gb RC2-ET0022 080500 012-d02 ET0022 Homo 420
438607 AW080237 Hs 252884 ESTε 420 451952 AL120173 Hs 301663 ESTs 420
455397 AW936332 gb QV4-DT0021-281299 070-g01 DT0021 Homo 420
417116 Z43916 Hs 7634 hypothetical protein FLJ12287 similar to 419
453247 T80198 Hε 111806 ESTs 419
430451 AA836472 Hε 297939 cathepsin B 419
414283 AW960011 Hs 154993 ESTs 418
452248 AA093668 Hs 28578 muscleblmd (Drosophila) like 418
450746 D82673 Hs 278589 general transcnption factor II, i 416
444797 AB018333 Hs 12002 KIAA0790 protein 416
445718 H79791 Hs 15227 ESTs 415
425783 AI026740 Hs 1948 nbosomal protein S21 415
414837 U24266 Hs 77448 aldehyde dehydrogenase 4 family, member 415
406710 AI708347 Hs 184014 πbosomal protein L31 415
424436 AW818428 Hs 4953 golgi autoantigen, golgm subfamily a 3 414
422343 AI628633 Hs 346823 gb ty77d05 x1 NCI_CGAP_Kιd11 Homo sapien 413
416207 NM 014745 Hs 79077 Homo εapienε, clone MGC 2908, mRNA, comp 413
406724 C14071 Hs 234518 πboεomal protein L23 412
449475 AI348027 Hs 108557 hypothetical protein PP1057 412
413828 L19067 v-rel avian reticuloendothelioεiε viral 411
416819 U77735 Hs 80205 pιm-2 oncogene 411
436674 AA725002 Hs 272018 low molxular mass ubiquinone-bindmg pr 411
405266 Target Exon 410
408996 AI979168 Hs 344096 glycoprotein (transmembrane) nmb 410
410704 BE076754 gb CM1-BT0601480200421-b10 BT0601 Homo 410
420851 AA281062 Hs 29493 hypothetical protein FLJ20142 410
423096 AA732684 Hs 278428 progestin induced protein 410
428328 AA426080 Hs 292812 ESTs, Weakly similar to 138022 hypotheti 410
429355 AW973253 Hs 292689 ESTs 410
433308 AA582718 Hs 291650 ESTs 410
443559 AI076765 Hs 269899 ESTε, Moderately similar to ALU8 HUMAN A 410
450850 AA648886 Hs 151999 ESTs 410
453785 AI368236 Hs 283732 ESTs, Moderately similar to ALULHUMAN A 410
406854 AA613705 Hs 252259 ribosomal protein S3 410
410768 AF038185 Hs 66187 Homo εapienε clone 23700 mRNA εequence 409
419612 AI498267 Hs 110613 KIAA0421 protein 409
434203 BE262677 Hs 283558 hypothetical protein PR01855 408
439237 AW408158 Hs 318893 ESTε, Weakly similar to A47582 B-cell gr 408
441374 AA043696 Hs 7822 Homo sapiens mRNA, cDNA DKFZp564C1216 (f 408
443415 A1056523 Hs 133472 ESTs 408
424338 W78816 Hs 49943 ESTs Weakly similar to S65657 alpha-1 C- 407
422305 AI928242 Hs 293438 ESTε, Highly similarto AF198488 1 trans 407
400233 Eos Control 406
421959 AW751497 Hs 98370 cytxhrome P450, subfamily IIS polypept 406
442622 NM 000435 Hs 8546 Notch (Drosophila) homolog 3 406
424795 AW102850 Hs 153177 nbosomal protein S28 405
446231 NM 002163 Hs 14453 interferon consensus sequence binding pr 405
452933 AW391423 Hs 288555 Homo sapiens cDNA FLJ22425 fis, clone H 405
427681 AB018263 Hs 180338 tumor nxrosis fxtor rxeptor superfami 405
409061 AI204994 Hs 7874 Homo sapienε cDNA FLJ21435 fis, clone C 403
413891 BE271020 tumor suppressor deleted in oral caπcer- 403
414004 AA737033 Hs 7155 ESTε, Moderately similar to 2115357A TYK 402
417035 AA192455 Hs 22968 Homo sapiens clone IMAGE 451939, mRNA se 402
410584 AB011112 KIAA0540 protein 401
417353 AA375752 Hs 348140 Homo εapienε mRNA, cDNA DKFZp586F1822 (f 400
423645 A1215632 Hs 147487 ESTε 400
430048 T65054 Hs 73605 ESTε 400
431113 AK000673 Hs 274337 hypothetical protein FLJ20666 400
434170 AA626509 Hs 122329 ESTε 400
434584 D57341 Hε 188361 Homo εapienε cDNA FLJ12807 fis, clone NT 400
435391 AA704588 Hs 58934 ESTs 400
446768 AV660305 Hs 110286 ESTs 400
448019 AW947164 Hs 195641 ESTs, Moderately similar to I38022 hypot 400
451831 NM 001674 Hs 460 xtivatmg transcnption fxtor 3 400
TABLE 56B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accession Genbank xcession numbers
Pkey CAT Number Accesεion
438091 22448 1 AK054860 AV652198 AV652192 AV652138 AV652127 AV652194 BE935919 AV652017 AV651995 AV651548 AV646063 AV651985 AV646184
AV646179 AW880409 AA345002 BF155189 BE068931 X56197 AL603014 AW953629 BM263546 BE550772AA701084 AI681352AA358689 AW938841 BF438147 W05391 H75313 BF326185 AV646335 AV651589 AV646340 AV651992 AV646384 AV646364 AV687497 BF155183 AV646370 AW797876 AI906821 X56196 BE833835 AA628440 BE833808 BF224205 AA709126 BE673807 AI923886 AA947932 AI276125 A1185720 AW510698 AA987230 BE467708 AW898628 AW898544 AI146984 AW043642 AI288245 AI186932 AI635262 AI139455 AI298739 AI813854 AI024768 BE699445 BE699444 AI707807 D52654 AI214518 AI004723 AI698085 AW087420 AI565133 AA845571 AW898622 BF110144 AW513280 AI061126 BF362770 AI268939 AI435818 BF475318 AI024767 BE174213 AA757598 AA513019 AA902959 AI860794 A1334784 BF108411 BM310532AW513771 AI951391 AI337671 BF095606 BF095601 BF095468 AW890091 BF095753AW243400AW898607AW898616 BF362762 AI922204 AW898625 BE699468 BE174196 AW102923 D52715 BE699456 D52477 D55017 BF955933 BG623563 AV646254 AA463522 BI003244 A1299190 W40186 BE174210 BF939091 BF434180 AW579001 T55662 H01811 T52522 BF945037 BF955938 D54679 D53933 R67100 BG925552 BF999056 R83430 Z29922 T85791 W03942 H63289 AI091537 BF086583 AA345570 H48870 H80720 T83523 BI039626 BI037700 R00353 BF155184 N98343 N79072 H01812 T55581 429978 35194.2 BE738425 BE738323 BM126944 AW629678 AW265195 AI916735 AI394255 AI573090 AI354442 AW612857 AI339558 AI919424 AI377532
AI354441 AI308821 AA772275 AW055215 AI589705 AI336532 AA806547 AV682125 H93575 AW071172 AW769904 AI863985 AW265018 AW196655 D79662 BE042393 N75017 AW014741 C75509 BE748621 H92431 AW079261 AW901780AA329482 AW960115 BI260621 AI767525 R31663 BI918664AW963196 C06195AI678018 442562 39593 1 AK056685 BG399272 AA187835 BF821903 AV660550 AV660556 AV660502 BG564397 BE379584 BF446961 AI653056 AW973709 AI653173
BG054997 AI266043 BI054879 AI656750 AI492830 AW021142 AI472184 AW170056 AI082443 AI167921 D59940 BI492088 H74180 AW130886 AI348677 AI278577 AA761517 AI698203 AA115535 AI264790 AW205074 AA860452 AA554902 AI000715 D62102 BE544768 AI376090 D59939 AW242249 AA525421 R34211 R34328 BF248064 BF241437 BF572759 BF218832 412636 1438 1 M77830 NM.004415 AF139065 BG681115 BG740377 BI712964 BG000656 AA128470 BI438324 H27408 BE931630 BE167165 AW370827
AW370813 J05211 BG698865 BG740734 BG680618 BG739778 BI765807 BM353403 BM353248 AW177784 AW205789 AW951576 AW848592 BE182164 BF149266 BE940187 BI060445 BI060444 BF350983 BE720095 BE720069 BE715154 BE082584 BE082576 BE004047 AA857316 BI039774 BE713818 BE713548 AW170253 BE160433 BI039775 AW886475 BM462504 BE931734 BF149264 AA340777 BF381183 BG621737 AU127260 AW364859 BF993352 BG223489 BE819009 BF381184 BE715956 R58704 AA852212 AW366566 BI090358 BF087707 BE819046 BE819005 AA377127 BE073467 BE819069 BE819048 BI036306 BG990973 BI040954 BF919911 AU140155 AI951766 AI434518 AW804674 BF752969 BE837009 BE925826 BF149265 AW995615 BE814264 BI039782 AU140407 BE144243 BE709863 BF985642 BE001923 BF933510 AW265328 BG436319 BE182166 AW365175 AW847688 BE818280 AW177933 BF873679 AW178000 BE082526 BF476866 BF086994 BF592276 BE082507 BE082514 BE082505 BF873693 AW068840 AW847678 BF804153 AW365157 BE813930 BE002030 AW365153 BE184941 BF749421 BE184920 BF839562 BE184933 BF842254 BE698470 BE931048 BF999889 BF368816 BE184924 BE159646 BE714632 BE184948 BG986845 AA131128 AA099891 W39488 C04715 BF096124 BE865341 AW799304 AL603116 BE149760 BE705967 BE705966 BE705968 AW848723 AW376699 AW376817 AW376697 BG005097 BF751115 BE696084 AW848371 AW376782 AW848789 AW849074 AW361413 BF927725 BF094211 AW997139 BE865474 BE185187 BE156621 BE715089 BE713297 BE713298 BE179915 AW799309 BF872345 BF088676 BE705939 AW752599 BG005197 BF350086 BE715196 BE715155 BF752396 BF093817 BF831190 BF752409 BE006561 BG959922 BF094833 BF094748 BF094583 AW377699 AW607238 BE082519 AW377700 BF349467 AI190590 AI554403 AI392926 AU158477 BI467252 AU159919 AI760816 BF082516 AI439101 AA451923 Al 340326 AI590975 BI791553 AI700963 AI142882 AA039975 AA946936 AA644381 BM314884 AA702424 AI417612 AW190555 AI220573 AI304772 AI270345 AI627383 AA552300 AI911702 AW166807 AI346078 W95070 AA149191 AA026864 AI830049 AW780435 AI078449 AI819984 AI858282 BI468588 AI860584 AI025932 AA026047 AA703232 AA658154 AA515500 AW192085 AA918281 T77861 AI927207 AI205263 BF082491 AW021347AI568096 BE939862AA088866 D12062AA056527AA782109W19287 W02156AW150038AA022701 T87181 H44405 AI910434 BF082513 AI494069 AI270027 AI635878 AA128330 BG681425 BE706078 R20904 BG680059 BG676647 BF764409 AA026654 AV745530 BI762796 BG287391 AW798780 BE706045 BE926470 AW799118 BF087996 BE002273 AW879451 AI571075 BE067786 AV721320 AI022862 N29754 C03378 N84767 AA131077 H30146 BE714290 AI686869 AI568892 AI915596 AW105614 AI887258 AI538577 BE926474 BE067737 BG319486 AA247685 AW798883 AW103521 BF989173 AW860878 BE939707 BE185750 BE714064 BE713903 BE713868 BE713763 BG950164 BE713810 AW365151 BG955489 BE005272 BF915937 AW365148 AI905927 BF992780 AW853812 BG954443 BI770853 BG679406 BG740832 BG681087 BG698430 AA455100 T87267 BE696209 BE696210 BI089483 BE006273 BE872225 AW391912 BE925515 BG677012 BG741970 AA026480 BE705999 BG677157 BE009090 BG681378 BE712291 BG961498 BG678984 BI040941 AA337270 AW384371 AW847442 BI058659 BE813665 W95048 W25458 AW177786 AA025851 BE931733 BF154837 BG949393 BE714441 AW996245 BE711801 AI284090 BE064323 BE719390 BE940148 BG991212 BF375714 BF349522 BG996267 T48793 BI013292 BE001925 AW365156 AW365154 AW606653 BF763109 BE931637 BE167181 BE713879 BF354008 BF678726 H90899 AW365145 W38382 AI498487 413787 '7612J BC003047 S80794 NMJ03405 X78138 AY007132 L08439 AW340648 AW131665 AI082748 AI470204 BI711078 BF350700 BI496963 AI087141 AA720684 AA862331 AA605146 BM313650 AI089749 AI359738 N69107 AW995424 AI086917 AI083995 AW340217 N99662 AI829449 AI089839 AI608761 AI342365 AI199076AA908944A1248943AU160053AI191245AI218477 AI077943AA864930AI310394AA872478AI279782W61343 AA565955 W46596 AA126874 AA223241 AA491574 R84813 AA491520 BG055114 AI469689 BE464590 AW664539 H67097 AL534332 C21397 AI085941 AW028427 BG939820 AI697089 AI039008 AI125315 AI655561 AW150042 L20422 X57345 BI458375 AU142852 BI666601 BE888276 AU119302 BI603754 BG705953 BI598754 BE296713 BG002538 BF951911 N29226 BE909424 AV698274 AV683116 AV708195 AA127798 AI124697 D54224 F08031 AA340253 BF923383 BM467808 BI546644 BG777200 BG705941 BG468577 AU127209 AW403970 BI597630 BI458091 AV689560 BI669267 BG506219 BI837163 BI667275 AA343750 BE783112 BF671405 BF954720 H67636 H69456 AA484894 BI869271 BF998207 N31547 BF945817 BF947918 N90630 BG980194 AA156681 BI493502 A 273118 A1473820 AA608688 A1359337 AV712091 AA084101 BF592036 H13301 AI864305 AA505883 AI423963 AW084401 AI917740 R69858 AA033631 N79982 BE885276 AI635674 AA096126 AA700018 AV707753 AI082545 AU145681 AA629032 AI421367 AA740589AA150830 AI248541 AA988608 AA150478 W65437 BM310234 AA262704 T28031 AI811116 BM272753 H21979 T15405 AA938406 F04963 AI188296 AW152629 AA905196 BG223058 AI831016 AI766457 AI811102 AA776573 AI922133 AA775958 AI261476 AA219489 AI688035 AI872093 BE537084 AW189078 D82630 AI123121 AL583492 BE350791 R69901 W65436 BE155392 BI089081 BE155394 AL120538 AW166100 AI359620 AH74338 N20527 W47413 AA155615 AI272249 H25293 BE614558 H69864 AW383484 H78021 H11617 R56892 H23204 N21530 R82499 AW383522 AA774536 AL534331 W94127 W46459 AI866231 AA513281 AA192465 H69844 W85827 AW383642 AW383529 AA171496 AL537424 BE814866 BF823254 R82553 AI809817 AI559406
410143 MH1244.8 AK000357 AI571830 AA579613 AA668790 BF939495 BF196886 AI990982 BF591561 AI809189 AW410232 BF739769 AH44392 BF438721 AI707495 AI423359 N52503 BE855784 N94367 AI023931 AA563662 AI744624 AI221298 AI299523 AI299520 BI491312 AI452711 AI360730 AA622643 AW195955 AA470473 AW392767 AI218127 AA873430 AA906005 AA748160 H89523 AW020252 AW664988 AA970424 AA879079 AI581622 AI361357 AA468498 AW008694 AA903275 AI187724 AH87718 AA890505 BF092771 AI066655 BE714172 BG289028 AW080390 BE001197 BF132049
426295 510.1 BE880923 BG390191 AW470082 AW014585 AI423255 BI714731 BG054894 AW780248 N31683 AW664132 AW467353 AI983152 AA617918 BF447795 AI088357 AA807328 AA576970 AI741153 A1755003 AI474016 AI422030 AI348114 AW997085 BM271753 AI363147 BM311311 AI146640 A1246771 AW512619 AI359020 BG054897 AI292234 AI215830 AI283836 C06205 AW503423 AW272680 N33205 AW873021 AA070724 AI753886 AW192487 AI087151 AA658909 AI346368 AI335677 AA825442 AW440066 AW131357 AW513210 AI082314 AI085455 BE551404 AA780704 AW008596 AI796964 AA917471 AI400531 AA668626 N72207 AI306482 AW440562 A1084687 AA347280 AA063536 BF477389 AI241662 AA931543 AA484310 AA812486 AI032216 AA665779 AI916336 A1350590 BF198106 AI433377 AI300638 AI672626 AI282741 AI351487 AW105544 AA973627 AW517914 AA715424 AA508454 BF334080 AI274618 AW367201 AW572619 AW469088 AA382095 AI368364 AH46934 AI357180 AI361181 BI911347 BI871044 AA136325 BF084010 BF084007 AA335788 AI920878 AA809614 BE932941 AI678261 C75308 AI148479 BE178174 W88513 BM013627 450377 12109.1 AB033091 AL520743 BE811813 N53332 N99716 AL561910 AA280655 BE710392 AV705100 AW293978 AW444556 AA281459 AI679751 AI873695 BG700891 BI553517 R80518 BG779771 BG534451 AA479402 AW961580 BF061430 AI857643 AI768486 AW512118 AA479302 AW770384 AW072470 AI041596 AI049699 AW592865 AA976261 BE879747 BG114119 AW183811 AA909938 BF571621 BF350794 BF351375 BE925699 AL050294 BC010371 BF982270 AL042656 BF095732 AW812618 BF095731 BG212397 BF678765 BI038602 BG388664 AW675337 BG289398 BE939598 AW805570 AA527097 AW150540 AI693720 AA743364 AI915793 N48185 AI573107 AA043474 AI351615 AI969490 AI910763 R50866 AI699181 N73808 H08164 425996 138046 1 BM006551 AA367152AW953705A1631833AW237429AW027804AA729038 BE503409 AI521935 BF739953 AA702982 AA557633 AA780065
AI218139 A 194264 D20120 AI082715 AI969980 BE857686 BE326711 AW953706 A1393749 AI383821 W67199 AI431759 AI796526 AI521794 AI796380 AW117545 AI749657 AI537634 N50122 427521 513212.1 AW973352 BF222929 AW016853 BF059130 AI651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 AI206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892 444060 6315 1 AK055070 AK055612 AK000174 BG619806 BG108086 AI741949 AI004176 BF891936 BF378565 AW197163 BE856860 BE245124 AW674411
AA490531 AW674981 AA740788 AW274758 BF512523 AI521278 AA548759 AI802431 AW051682 AI628247 AI799606 AW088103 AA236549 A1191529 AW273168 AI168451 AW073812 AW090611 AW003593 AI215845 AI799616 AW474940 AA954927 BM193740 AW662704 AW090127 AA969444 AI080438 AA552500 AW237538 AA481060 AI246378 AA565227 AA398921 AA207051 AA721378 BF438608 AI086295 AI886630
AA904112 AI864588 AW271985 AW078868 AA725342 BF326598 AA843572 AI082536 AA766664 AI453279 AA435673 AI619515 AA879080
AA234592 AA890223 AA766824 BI259822 AA393631 AW968840 BE940639 T83865 BE762742 AW897470 W05809 N41323 T87376 R68544
H88711 BI087136
413497 15180021 BE177661 H06215 BE144709 BE144829 430068 1177709 -2 AA947566 409208 10117.2 AK074047 AI144342 AW014280 BM145128 N28267 AW206231 AA989041 H93197AW594063 BG236296AW236606 AW081031 AA765843
BM144372 AA989341 AI824838 AI963970 AI637671 AW196330 BG427526 BM148789 BF893644 BF881946
422960 11862.2 BF090249 AW954947 AW890487 AI305236 D60845 D60537 AA825429 W36294 AW890410 AW088235 BF740240 AA448709 AI350279 AA879119
AA319510 BE702077 BE699015 BE702046 AW901293 T99319 D81708 BF475488 D60383 D81751 BE699260
434280 1474904.1 BE005398 AA628622 AA994155 434442 111738.1 AA662701 AA633929AA737415 410730 114639.1 BG427950 AA826016 AI903441 BG939868 AW979154 AA640872 BG547134 AA457091 AW368860 W88852 R94779 AA088823 438089 224484 BM475665 BE644917 AW770789 AW952971 N64863 BM263259 AI224545 Al 184866 N69114 AW518902 AI440169 AA809472AV654440
AA281642 AU185230 AW337382 AI872923 AI537113 N73882T83378 H63731 BF671764 AW897824 AI811204 AA344646 BE009112 BG899664
H91240 R60548 N41701
425284 3834.5 BM476120 BE672181 AI697653 AA938187AI280879 AW340123 AI912727 AI081775 AI089556 AI191349AI871604AI631607 AI890800AI701917
AW771624 AA663041 AI991576 AI160622 AA771763 BE089784 BE089788 AI222942 AW418516 AA329211 AI095736 BE550294 AA738345
BE218683 BE670548 BG149505 BF061776 D19821 BE005786 BE178892 BE005728 BF841237 BE005648 R27634
422689 874209.1 AW954733 AA315006 AW856665 414405 112689.1 AL047596 AA393792 AI670731 AI037957 AW874364 AI038137 N62286 AI241379 BE501096 AW090696 AI927369 AI669226 AI369437 AI371075
AW612409 AI686711 AH 83289 AA477717 AI076122 AA635190 AA700984 AA781508 D81020 BF575223 AI356183 D79312 AI375558 H61111
BG283489 BE090666 BE090664 BE090662 H26545
442495 928718.1 AI184717 AW518883 AF121173 450139 34017.1 AK001838 AU135179 AU134241 AV651702AV650032AV651304 AV650101 AV651263 AV651888 AV651866AA628554 AV651355 AV651174
AV651172 AW856145 AU117599 AU135386 BG254665 AA166919 BG483981 A 809606 BG494194 AA622811 AI676156 AA687804 AI701729
AU133725 AW961387 AU144387 AU151757 AA551031 BE675412 N34769 AA713483 AI890079 AI588918 AI361889 AI209020 AA668981 AI240990
AA741144 AA490899 AI200221 AW589574W96201 BG154182 AV655159 AA328145 N36348 AI081357 N76715 AA693346 AA742488 A1269719
AA897483 AI886459 AU155873 H04255 AW243986 AA557749 AI286227 R68691 R33453 AW388097
406819 0 0 AA908472
424677 2518 37 U09414 NM.003438 AA503545 AI022449 AA043458 AA766074 AA765442 AA805052 AI028211 AW609708
438980 917280 1 AW502384 AA828822 AI982587
451129 1495511.1 BE072881 AI762181 BE072946
432666 144 7 AA558585 AA565499 AI360576 AW204069 AA991648 AA864939
418259 133853 1 BM310925 AA426110 BM310629 BF434286 AW015091 BF475996 AW118867 BE675186 AI688568 AI453594 AW590589 AI652425 AI827969
BF056946 AI802866 AI393380 AI476224 AW590639 AW136271 AI458252 AI524726 AA843768 AA782158 AI336058 AI097532 AW451563
AA459408 AA459633AA418444W23607 BG940150 AI493445 AW054729AI221929 AI868744 AA215405 AA766713AA621546 BF928317
BE464132 AI990909 AW271459 AI262061 AA215404 N74332 BG940151 BG952261 AA972115 W96315 AA689586 R69057 BF766886 BE769254
W05240
451653 MH115364.1 BG119563AW975776 BG498478 BE245304AW450934 BF508792 AA599489 AA599477 AI805268AA055489 AI128758AA761425AA731858
AI302271 BE219432 AA687294 AA018972AW629429 Z45675AW961626 T30940 R34554 T84712 BG986694
433162 2167905 1 A1742311 A1025842 AA578843
406870 0 0 AA075144
445493 423456 1 AV711317 AI809938 AI808768 AI240593 AI915771
406797 0 0 AI432224 AW276890 AI499346 AA937014 AA653573 AI318525 AI246219 AA961591 AI270640
441623 3362.1 BC022413 BE395396 BF754175 AA506621 BE706665 BE706678 AA723159 BE153169 BE706729 BE706558 BE153312 BE706706 AW371853
AW371849 BE153241 BC017410 AI337912 A1090244 AW090300 BE219837 AI623661 BE501576 BE501734 AI742232AI023964 AI458424
AA975373 AI288904 AI984583 AA890325 N32562 AI358102 AW241694 AI038448 AI672071 AI018389 AA576391 AA977874 AW189392 W37448
AA612894 AI277548 H89551 AI699774 H89365 AA315805 AW579186 BC014584 BC014581 AW780125 AI672414 BE328145 AW600919 BF031306
AW172758 BE708322 AA345675 BE875779 H28241 H25318 BF540913 BG179688 BF110202 AA528775 W37573 BE041644 AW366504 BM129522
BM129822 AI122760 BE718200 AW887496 AA149420 BE706307 BE539395 BE748765 AI373653 R75904 BF979185 BF691393 BG495595
BI094458 BE706702 BG496559 BF248373 BG494800
430504 5477.6 BE219720 BF475241 AI571723 BE219848 BI789268 AI224899 AA724864 AW771467 AA480255 AW845616 AI440295 H52800 BE218790 AI681575
AW300064 AW262133 H21568 AI363015 AI884914 H86948
433891 6472901 AW182329 AA613792 T05304 AW858385 455263 26143.1 BG216963 BG164885 BG213710 BG204771 BG193014 BG197556 BG217481 BG198185 BG183594 BI596425 AA115605 AI589156 BF439839
BG188832 AI359615 BG190473 AI024233 BF439574 AW118065 AI672797 AA610042 BG212008 AI204382 R70913 AA033534 AA781036 AI627278
AA307285 AA034218 BG482749 AW162429 BI602460 AA721969 AA476516 AA476416 AA903019 BF110864 AA307286 AA115471 AW964555
AA423826 AA115129 AI419107
406806 0.0 AW088535 AI889321 AA954221 AI337552 R42581 AW194670 AA064862 AW001147 AA864374 AA630699 AW276176 AA676615 AA857965
AI625428 AA580792 AA582038 AA581668 AA658065 AA828156 AA857160 AA936103 AI149335 AA936925 AA581684 AA954198 AW238461
AI281504 AI265812 AA583267 AW236162 AA876535 AW304286 AW474334 AI559415 AI589241 AI660952 AA641137 AI431696 AI688844
AA552513 AA564954 AW090553 AI205612 AI245753 AA954883 AA947909 AI866014
406794 0 0 AI890243
431155 1235742.1 AW971213 AA493925 AA493567 AA876839 AA934462
414150 2305332.1 T40644AA136139AA136026
430915 197844.1 BG425760 BF997600 N48516 W73454 BF816344 BF997601 AA488953
436716 2472838 1 AI433540AA804981 AA728984
449625 249224.1 BI918168 A 779760 N48674 AI375997 AA235370 BG699146 AI913631 A1498402 AI016320 AA323193 R49021 D59344 BG986750 N45526
BG986917 T61382 R49391 R45432 AI203107 R35004 F07491 R25094 R35360
430283 1418.1 BC013728 BI084032 BF090365 BE410706 N36391 W80436 BF813124 R90857 R62778 H00591 H02329 AA355285 AK000826 BC008721
BG744004 BG479141 BG823656 BG479061 AU121103 AU138176 BG702567 BI599840 BG422775 BG700944 BE280747 AU138529 BE269929
BG704110 AU123329 AU122058 AU138135 BG723106 BG722291 BG831041 BG705239 BE740517 BE207133 BE252867 AU139772 BG714385
BF568538 BE304393 BF971755 BE267965 BE272012 AU135396 AU124535 BI551682 BG700612 AI815488 BG475195 BE388273 BE391517
BM148991 BF929247 AV653435 AW250299 AW249189 BF093150 BF093173 AW205325 BF057101 BF000551 AI341108 AL162009 AK026136
BE907957 W73238 BI711467 BG926027 AI816428 AA837518 AI754405 BG179142 AA481485 AW023435 BE855747 AI885101 N52163 AI016096
AI090204 BE677045 AI523320 AI126855 N26501 AA043680 AA976459 AI039590 AI937917 AI361000 W94866 AI375797 AI079801 AH68236
AA599882 AA084368 AI342635 AH 90294 N26093 AI085234 AI298169 BF939715 AI223164 H98704 BE218925 N29394 AI918735 N41520 AI147784
AI918796 AA854317 N22193 AA199850 AI149728 AA121263AI051074AA565116 AI097349 N22209AA552917 N33151 D52422 BF477483
AA476599 AA525787 AI279198 D53353 AA738063 AA558406 BI496334 AA999948 AA425847 BI496335 AA909624 BF197591 AW023259 AI652819
T31424 AA088213 T31115 AI206650 AA976796 AI948989 AW248762 AA449265 AA290687 AI682521 AA310227 Z38743 AA935369 AW119141
BF941087 AI470657 AI349451 AW079338 D45665 N21640 T30071 AI446705 R60220 BE833481 R49680 R70049 R41223 R32402 R69984 R70111
BM476906 BE293615 BE382443 BF155692 BE720638 BE931983 BE720594 BF085890 AA336953 BF081638 AA359915 AA384116 AA360142 BI667664 BG823235 BE315559 BE301958 BE891114 BG826267 BE253680 BG979094 AV722757 N67629 BG997927 BI915769 BG680692 R62777 BE251116 H56358 AW369586 BG677759 BI044604 R75787 BE770960 H69529 R69983 AA259238 R97827 AA310379 W01103 AI873384 AL554578 BF038102 H87182 H87517 H01574 T52573 N28881 AA301397 T92375 R68401 AW800466 AI268172 BE876949 D54019 AI909769 AW798415 BI222383 AI393171 C15260 N26959 H17129 T53095 T52494 R68602 AI364765 BF687869 AI817035 AW105354 BE293820 H14206 BI093066 C14063 AL534349 BE255883 BE254088 AA428399 AW579360 AW579381 N53144 D60748 D54020 BG292106 H96705 D52423 T36174 D54161 R73016 D55021 BI857200 H83444 BI016954 D54163 R15563 BI818664 BE152207 BI048502 BF885667 BE613212 BE165773 BF149332 AW607045 BE305200
409019 32320.4 BM480413 N28908 H39792 BE240826 BE882093 BE240827 AW868637 BF739795 AA700834 AA769597 AA489668 AW968806 AW085196
AI093280 A1218457 AA063138 AI632958 AW515005 AI570530 Z41724 AA748789 AI696584 AA062544 AA773643 AA490285
433009 2142268 1 AA761668 AA573621 R09670 R92814 415995 2117.1 M95678 NM 004573 AL530754 AI439623 AW374413 BF898880 AW630959 BF875526 AW402206 BF818690 BF893068 AW504110 AW408049
BG002913 A_L530753 A1524064 AW769231 AA464970 AA293723 AI095051 AI953375 AI982938 BM146050 AW575804 AA962489 AI655426 BM146046 T28538 BE241936T89023 BI910963 AI416986 AI767111 AI422290 AW468260 BE676853 AI656771 AI961755 F04675 AA682826 AA737606 BM194382 AA912021 AW183098 BE676682 AI962227 AI591366 AA621765 AA293724 R51642 F10194 BI909727 BF892632 AW950600 AW950138 BG258587 BF892649 AI800647 BF892710 AA353176 BF894726 AA465038 BI040869 BI837749 BE244320 H18054 T74300 AW797026 AA926790 F32814 AW751282 AI933994 AA578823 T78372 BF899896 BF882808 BF974969
434372 8587791 BG622121 AA631424 AA988296 AA631373
436812 6597791 AW978773 AW298067AA810101 AW194180 AA731645 AI690673
406799 00 AA908548
430968 12371151 AW972830 AA489820 AA527647 AA570362
418905 5171 B 469076 AA533027 AI127512 A1368802 AA533141 AA700560 AW576028AI610851 A1435361 B 129172 AW474544 B 128899 AI814292 AW502039 AA531243 BF941858 AW502037 AA702337 AI419854 AA662755 AA934364 AI300510 AI291136 AA505263 AH44527 AI076919 AI633534 AI242473 AA938561 BG055372 AA512894 AI671356 AA962403 BF808010 AA663911 AA847056 AA513301 AA369069 AA377265 BG291206 AA402298 AA885766 AW801002 AA302290 AI305842 AW800873 AA302492 AA478427 AI817291 AW801104 AW801028 AA865744 BF155979 AI374743 AA478431 AH59846 AI369757 AI800672 BF435788 AA255451 AI937707 AW006198 AI280363 BF062434 AW801115 AI919181 F28413 W04214 AW152380 AW901567 AW901570 AA886371 AA384251 AI302846 BE701902 AA931606 H42673 R33703 AW901556 AA009816 AW901568 AW352200 AA256558 H15928 BI087170 AW800530 AA369068 N98562 H28652 N34644 H97650 H00956 W70039 AH42831 AA009817 F37136 N70289 AA531347 R72374 H27488 R66605
406813 0.0 AW276131 418876 121279.1 AA740616 AA654854AA229923 447197 2176805.1 R36075 R36167 AI366546 457068 1196.1 BC022444 BC004138 NM.000970 BC020679 X69391 D17554 BC013863 BG779630 BG574189 BG571986 BG494603 BG575713 AV702244
AU145720 AI568177 BE350654 BG943995 AA730918 AA634024 AV744673 AI611573 AI613381 AI613403 AI250148 AW301759 AI312307 AI376488 BE139682 AV743357 AI371951 AI613376 AI613570 AI345719 AI312458 AI612697 AI334453 AW268747 AW268318 AI343026 AI335454 AI313096 AI308011 AW075176 AI348782 AI334479 AW268332 AI611433 AI371906 AI312459 AI371647 AI370051 A1335217 AI312262 AI610971 AI348798 AI613378 AI612698 AI348772 AI345434 AI345283 AI312292 AA775853 AI611363 AI345286 AI318305 BF054854 AI613384 AI348808 AI802857 AI609452 AI583301 AI349258 AI345645 AI345011 AI340442 AI335410 AI310907 BF055880 BF055774 BF055754 BF054712 AI583261 AI309664 BF054905 AI370092 AI349212 AI345583 AI334554 AI312242 BF055856 AI612686 AI611382 AI610952 AI345301 AI312235 AI610936 AI609836 AI340650 AI312472 BF054840 AI802838 AI345448 AI336508 AI313098 AI312293 AI312277 AI254912 AW302091 AW074788 AI611968 AI611948 AI583362 AI583284 AI583245 AI379398 AI371935 AI340564 AW301840 AI862239 AI612025 AI611869 AI609852 AI345449 AI312375 AI312318 AI311993 AI310895 BF057960 BE178604 AI802860 AI612115 AI611886 AI370059 AI313286 AI802856 AI611438 AI311987 AI802821 AI312997 BF054711 AI611889 AI376483 AI252445 AI611577 AI349139 BF054925 AI802840 AI583286 AI340739 AI612041 AI345196 BF054833 AI308909 AI611883 AI313275 BF477097 AI609466 AI348792 AI340468 BG944254 BG941457 AW302007 BG944413 BG941475 D58042 AA328428 BG429596 BE395392 BM424161 BF663310 AV727364 BM473884 BG531178 AA307591 BF965435
440638 3711651 BG009500AI376551 AA897445 T87714 400281 9758_4 BE564506 Z47727 BF028489 BI597545 AA152273 AA730753 W07504 AA406507 AA316220 AA424683 N35844 N72473 AA442109 W01788 AA747605 AA235894 N41438 AA382786 AI906934 AI906935 BF091197 N85572 N75678 AV758098 BE719745 BE719744 BE719735
406781 00 AA639388 AA584945 AA776364 AA776365 AA865528 440129 2607882.1 AI732997 AA977633 AA865818 438869 521341 AF075009 R63109 R63068 419970 13569.1 AK055270 BE348291 AH90289 AW612022 AI269506 AI266578 AI269675 AW271406 BE879851 BF574163 BI497126 AW903775 BI917368 AW150900 BF244813 H79201
432586 66331 BC022881 AU150944 BG750783 AW754175 AW857737 AI911659 AI050036 AA554053 AI826259 AA568548 426395 22291.3 AK057067 BF111915 AW249706 AI222199 AI887251 AI818753 AI244687 AW135782 BF476693 BF060935 AI197928 AW251092 AI685636 AI685630 BE673458 AA932894 AW205200 AA720784 BG236866 AI583152 BE677464 AW149338 AI926439 BG031285 BF915924 BG982583 BI060025 BG991393 BE830027 BE151985 BE152208 BE152002 BE818337 BE717581 BE818354 BE830030 AA377477 T51255 BF920761 BG170636 N90052
445093 1759631 AI207197 BF773544 AW196462 438962 1957631 AI207343 BF813684 BF928775 AA828585 425097 231752 AF070570 BF439282 BF109960 AI480268 AI038060 AW082339 BF516290 BE218214 AI469956 AA039955 BE644674 AI861871 AA766231 AA845840 W85716 AA676253 AI087188 AA022908 AW953178 T33195 BF594711 AA488969 R55652 D81245 D80778 D81560 AW960933 BF930897 BE698103 AA040024 BF515960 BE168475 AA453247 AI267601 R60894 R44223 T33194 AA114936 W31640 W38829 W39109 AA004849 H41952 W88634 BF031932 BM423354 AL041825 H29654 AI908178 W85754 AI905762 AA309860 C04540 AA340246 H84669
437386 5541 2 BM476605 BI545004 BI834636 BG112453 BI199049 BG112759 AA149846 H97925 AA306121 AA313204 W52451 AI734997 AA931168 AA429766 N47913AA584321 BF940241 AI083648 AI089410 AI347705 AI343661 AI186232 AI889031 N9B464 AI820039 AI459034 AV652512 AA622990 BE857200 AA932998 AA740573 AI826264 AA865683 AI344550 AI027349 AI056087 AA442777 AA603724 AA873347 AI056717 AI092185 AI032895 AA535689 BF806025 BF806061 BF805985 BF746099 BF746097 AI309259 AI597603 BF806066 AI090653 AH29205 AI248410 H72993 AW615341 BF805990 BF805982 AA993819 T34373 T35604 H56242 AA648145 T35907 BF808691 N94015 AV703438 BG774276 H82341 R76371
418866 245947.1 T65754AA229658 AA229857 400244 12188.1 X79449 BC017853 AL121035 BF196384 AW119044 AI028023 A 451110 A1971911 AW015069 AI079170 AI376367 AI264113 AA829646 AA737579 AA449679 AA740864 NM 001111 U18121 AL567297 BG773801 BF973874 AV687104 AA527579 AA843525 BE706355 AI074589 AI523475 BE890249 AW406263 BE074258 AV729485 BF809610 BG058619 AA677244 BE179838 AA622264 AI460106 AA740411 AI499168 AI078223 AI682923 BE696559 AW375385 AA788739 BG984978 Z40874 T17054 F09669 AW844043 U10439 BI711870 AW245957 AU158567 AA679305 AA679316 W72510 AI346029 BG059762 AW251062 AA132373 AI925621 AI860230 AI340172 AW192891 AI707980 AI094937 AI042115 AI200901 BE328452 AA644678AA551209 BE351065 AA970761 68609 AW002028 AA160826 AI422774AW873114AW073597AW664483 AI218710 AW020550 AW190607 AI984545 AI871921 AI333970 AI452887 AI818335 AA398655 AI554424 AI274187 BE465703 AW512940 AW241366 AI923954 AA576649 AW168294 AA813181 AA912168 AI049738 AW514073 AA548255 AI569630 BE710031 AA244182 AI341697 AA563904 AI537990 AW517908 AW172943 Z39498 AI750294 AW150414 AI253293 BE825720 T31860 AW150775 D20310 AA150892 AU133933 BE781148 AL038957 BF910979 AA352297 BG988142 AW372175 BF229106 AW866705 BE093482 BG990396 AI499917 AA054452 H05484 AI828502 BM467331 AU140570 AL135417 BF947202 AW391926 BE813418 BF998473 T92021 BI021048 BM048783 AW501366 AW501342 AW501549 BE939021 BE707147 BE160974 BE305207 N49011 AA947119 AA678801 BE536876 AW897428 BG329648 BG818540 BE542344 BI919250 BI253018 AW130996 BE074249 BE895428 BI034862 BE083277 BF952166
418304 1093209_1 BE883520 BI057842 AA215702 AA215703 AA368006 BE006876 BE066555 438141 1173217.1 AA778849 AW946871 AW946782 AW946955
455397 1163608.1 AW936332 AW936341
413828 9453.1 BC011603 BG479117AU124990 BG829759AU143705 BG701663 BG699781 AU131718 BE515064 AU121812 BG898850 AL558461 BM151887
AU128758 BM263692 AU099013 AI241350 U88316 AW058398 AW469340 BF683967 AI470140 AU150993 AA633376 AW150821 AA536142 AU148749 AI620647 AU151769 AU 153404 AW070666 AI457758 AU153077 N99966 AW050940 BG055674 AA506657 AW301529 AI918646
AI611235 AI266081 AI334542 AW071277 AI312434 AW303114 AI436544 AI436466 R22972 AI472987 N77886 AW072883 AA318683 D19761 AW050566 AI312433 AA328444 R72435 AA430721 AI142599 AA582290 AU148896 AA721233 AW628132 R93935 AA100710 BI520773 AI934172 BG222461 H85359 AW074639 AA017117 BI026412 AL582142 AA443547 AA586793 AA777535 AA693844 AI018661 AA577422 AA522800 BF054818 AA102378 AA757993 AA687769 R55540 AA505784 BI820705 BI767939 410704 1054673.1 AW877458AW877524 BE076922 BE166912AW840534BE076754AW797829 BE166905 BE166926AW877462BE166927 BE166932AW877523
BE166917 AW877529 BE166928 BF351394 AW877522 AW877528 BE166861 BE166866 BE166913 BE166919 AW877456 AW877537 BE076866 AW840571 400233 11259 1 BC004324 NM 001020 BC00797 M6085 BM050628 BG829809 BE385504 BG744451 BI826914 BE440007 BI260656 BE39511 BE389334
BE255792 BI194169 BI668218 BI194376 BG716213 BG714408 BE392513 AV722219 AW328077 BM424171 BI828267 AW958606 BG831252 BE392943 BE394033 BI858915 BI668334 BE621019 BG706995 BE791985 BF967484 BI193635 BG761859 BM466537 BG747165 BG827488
AI133550 BM011511 BI227282 BG489212 BG478388 BE727789 BI160880 BG831707 BG324692 BM470427 BI083889 BG831605 BG754114 BG420536 BF308210 BE384213 BG832271 BG828032 BG481641 BF205675 BE899041 BE271558 BI193807 BI159866 BG473786 BG397178 BI194428 BI117210 BG768326 BG759507 BF975645 BF343657 BM020598 BG831082 BG829943 BG829501 BF306557 BE562511 BM050145 B 017978 BI193934 BI160764 BM60371 BG754991 BF973348 BF663234BF032537 BE388168 BM009051 BH92794 BG831002 BG830459 BG764737 BG761808 BG481705 BG104314 BM464565 BI261500 BG831857 BG831684 BG829852 BG765030 BG760419 BG760268 BG749762
BG480900 BG419627 BG248771 BF975542 BM042233 BI161149 BG831302 BG830033 BG829626 BM050064 BI193014 BI161360 BG822729 BG110091 BG106500 BI258369 BG831982BM458301 BM019513 BH61350 BI114178 BG481969 BG474870 BF974048 BF971122 BE741405 BE395269 BG832027 BG831469 BG490895 BM413638 BG943529 BG831012 BG829471 BG686284 BG337575 BG336551 BF206677 BI258301 BI160946 BG105893 BF183072 BM459542 BI193881 BG832043 BG831323 BH94545 BH60968 BG755930 BG706018 BE743865 BM465145 BG831227 BG774290 BF683451 BE907161 BM045391 BH94396 BH61269 BG747091 BG546643 BF984863 BI160206 BI226402 BI226336
AW328236 BG339458 BF972634 BE909808 BI160988 BI160251 BG828764 BG826860 BG758360 BF568228 BI818282 BI457127 BG831491 BG759864 AI830010 BF568381 BE907238 BI161172 BI116773 BG827153 BG825088 BG335419 BG109404 AI929068 BE906354 BE408564 BM045000 BG339617 BG282794 BG335767 BE907263 BF568921 BG829961 BG479305 BG260397 AI922228 BE301975 AW516055 BG480919 BG480626 AW196817 BG336261 BE906157 BE395717 BE391427 BH92954 BG829757 BG476379 BE301536 BE394727 BE257695 BE905344 AI433577 BE894416 BE886992 BE409223 BF034756 BE904077 BG830886 BE909153 BE907998 BE395767 AI871751 BE744523 BH92663
BG831669 AI000225 BE743836 BE272515 AA628078 BM463802 BE393375 BE393033 AW170187 BE730961 BE395410 BE744572 BE392297 BE391448 BE390780 BE388821 BE258477 BE905970 BE901567 BE898833 BE880326 BF726889 BE910504 BE390753 BE390131 AA650542 BE744156 BE394125 BE742207 BE395265 BE392942 BE894336 BE378222 BE906926 BE904650 BE393704 BE620999 BE515162 BE378753 BE272370 BE907458 BE612801 BE392484 BE907636 BE907353 BE910491 BE909796 BE905331 AW248173 AI683576 BE908826 BE620180 BF037570 BE908312 BE615015 BE256977 BE746875 BE394133 BE391478 BE910068 BE907185 BE742109 AA995746 BE561195 BE908825
BE906472 BE906509 BE906017 BE910442 BE514657 BI261969 BE741707 BE392216 BM042793 BF570283 BI262119 BE395707 BE378298 AW327827 BE394422 BF569178 BE263240 AI700512 BG830290 BF569308 BF569156 BH94587 BE390831 BG745096 AI681675 BE395674 AA136372 BE279892 AA442822 BE384898 AA313519 AI878866 AA305904 F33366 BE394852 F29153 F33618 AH 33637 AA300009 F34063 F29455 AU099691 AI905085 AI906656 AA343249 BE388691 AW404280 AA379888 F29022 BF089981 F31013 F24305 413891 823 1 BE271020 AI925430 AI806151 A 129911 AA828002 AW003539 BE042625 AI287859 AW778973 AI621173 AI991000 AA846016 AW150029
AW169748 AA649945 AI358496 AI470921 BF434211 AW513748 AW451232 AI953739 AI249448 AI040580 AI655280 AI637976 AW194345 AW611997 AI367197 BF064039 F29558 AI537342 BF593207 AW879538 AA973211 AI674328 AW879559 BF061961 AA481914 AA426532 AA426653 AA480106 AW243290 BF513102 BF346057 AI763358 AW003726 AI139045 AI570748 AW237602 T57492 BE887212 AI969311 AA133045 F23464 AA576416 T15590 AI650891 AI950958 AI983931 AW515101 AI650820 H81989 AA508473 410584 35319 1 BF828833 A1968217 AI651409 AI760574 AI147562 AW001418 AI146791 AI650589 AI952939 AI432373 AI964094 AI963870 AI420438 AI336803
AA809634 BF590826 AA741075 BI712639 AL134637 BM264338 AA527993 AI867208 AI439038 AI684987 AI631696 AI587126 AI637622 AI651931 AI867525 AI783674 AI638281 AI825752 AI339197 AI653411 AI341372 AI673213 AI673191 AW779768 AI627934 AI921836 AI741634 AI382284 AI741624 AI401569 AW190430 AW196390 AI829182 AI523816 AI760522 BE505014 AI917343 BG818909 AW009307 AA927544 AA825621 AA829400 AA527307 AI887999 AI865022 AA885063 AA653458 AA483816 AA836167 AA505879 AA421004 AA252626 AI380678 AW196980 AA649133 A1742276 AW015700 AA595019 AA877835 AI701658 AA729793 AA535004 AA926792 AA505113 AA603726 W68390 N90130 AA489461
AA830462
TABLE 56C
Pkey Unique number correεpondmg to an Eoε probeεet
Ref Sequence εource The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham, et al " refers to the publication entitled 'The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489-495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide posrtionε of predicted exonε
Pkey Ref Strand NLposition
402474 7547175 Minus 53526-53628,55755-55920,57530-57757
402145 8018280 Plus 113086-114800
401091 9958240 Plus 94760-94898
401466 6682292 Plus 28748-29023
401113 9966541 Minus 19419-19959
406542 7711499 Plus 117335-118473
405086 8072509 Plus 73664-73841,74081-74217,74610-74779,7492
401846 7712190 Minus 82775-82823,82912-83022
404854 7143420 Plus 14260-14537
405266 4156171 Minus 63337-63552
TABLE 57A 703 genes upregulated in testicular cancer relative to normal body tissues
Table 57A lists about 703 genes upregulated in tesficular cancer relative to normal body tissueε that are likely to encode proteins amenable to modulation by εmall molecules, peptides, or antibodies These genes were selected from 59680 probeεets on the Eos/Affymetnx Hu03 Genechip array Gene expresεioπ data for each probeεet obtained from thiε analysis was expressed as average intensity (Al), a normalized value reflxting the relative level of mRNA expression The protein products of these genes often contain one or more domainε indicative of have oncogenic function or of transducing intracellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death domain, 7tm, phosphatase or lon.transporter) Certain predicted protein domains are noted Pkey Unique Eos probeset identifier number
ExAccn Exemplar accession number, GenBank accession number
UniGenelD UniGene number
Pred Prol Domains Certain predicted protein domains Abbreviations used TM, transmembrane domain, SS, signal sequence, =Y, very likely to contain, =M, likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276280)
UniGene Title UniGene gene title
R1 95th percentile of testicular cancer Als divided by the 50th percentile of normal tissues Als, where the 10th percentile of all normal tissue Als was subtrxted from both the numerator and denominator Pkey, ExAccn, UnigenelD, Unigene Title, Pred Prot Domains, R1
424687, J05070, Hs 151738, matrix metalloprotemase 9 (gelat ase B, 92kD gelatmase 92kD type IV collagenase), matrix metalloproteinase 9 (gelatinase B, 31 23 440119, AA865455 Hs 125331, ESTs, Moderately similar to unknown [H sapiens], ESTs, Moderately similar to unknown [H s 2737 421241, X91817, Hs 102866, transketolase like 1, transketolase like 1, 26 89 431840 AA534908 Hs 2860, POU domain, clasε 5, transcnption factor 1, POU domain class 5, transcnption fxto, 2503
435918, AF263538 Hs 86232, growth differentiation fxtor 3, growth differentiation factor 3, 1988
432666, AW204069, Hs 351118 ESTs Weakly similar to unnamed protein product [H sapiens], ESTs, Weakly similar to unnamed protein , 1774 419556, U29615, Hs 91093, chitmase 1 (chitotπosidaεe), chitmase 1 (chitotπosidase), 1764
452838, U65011, Hs 30743, preferentially expressed antigen in melanoma, preferentially expresεed antigen in mela, 1706 417886, AA214584, , ESTs, ESTs, 1595
412265 AA101325, Hs 86154 hypothetical protein FLJ12457, hypothetical protein FLJ12457, 1593
425572, AB011076 Hs 158307, uπdifferentiated embryonic cell transcnption fxtor t, Undifferentiated embryonic cell transcπ, 1582 423905, AW579960, Hs 135150 lung type-l cell membrane assxiated glycoprotein, lung type-l cell membrane asε∞iated gly 15 11 419741, NM_C07019, Hs 93002, ubiquitin carrier protein E2-C, ubiquitin earner protein E2-C, 1508 427584, BE410293 Hs 179718 v myb avian myeloblastosis viral oncogene homolog like 2, v-myb avian myeloblastosiε viral oncogen, 14 17
418696, AW959433, Hs 326290, hypothetical protein FLJ12581, hypothetical protein FLJ12581, 1358 416819, U77735, Hs 80205, pirn 2 oncogene, pιm-2 oncogene, 1320
414034, U89277, Hs 305985, earty development regulator 1 (homolog of polyhomeotic 1), eariy development regulator 1 (homolog o, 1293 454077, AC005952, Hs 37062, insulin like 3 (Leydig cell), insulin like 3 (Leydig cell), 1290 432730, AI066520, Hs 131358 ESTs ESTs, 1284
446293, AI420213 Hs 149722, LIM domain transcnption fxtor LIM-1 (hLIM-1) mRNA, LIM domain transcription factor LIM 1 (h, 1274
423354, AB011130, Hs 127436, calcium channel, voltage-dependent, alpha 2/delta subunit 2, calcium channel, voltage dependent, alph, 1246 450581, AF081513 Hε 25195, TGF-beta 4, TGF-beta 4, 1242
450719, AI096837, Hs 21349, ESTs, Weakly similar to RB8B.HUMAN RAS-RELATED PROTEIN RAB 8B [H sapiens] ESTs, Weakly similar to RB8B.HUMAN RAS-R, 1226 431462 AW583672, Hs 256311, granin like neuroendxπne peptide prxursor, granm like neuroendxnne peptide prxu, 11 96
431354, BE046956, Hs 251673, DNA (cytosme-5-) methyltransferase 3 beta DNA (cytosιne-5-) ethyltransferaεe 3 be, 11 91
402199, , , Target Exon, Target Exon, 11 85
424578, AK001973, Hs 150890 hypothetical protein, hypothetical protein, 11 81
416350, AF188625, Hs 189507, phospholipaεe A2, group IID, phospholipase A2, group IID, 11 67 439979, AW600291, Hs 6823 hypothetical protein FLJ10430, hypothetical protein FU10430, 11 57
410048, W76467, Hs 343874, proline oxidase homolog, proline oxidase homolog, 11 42
442573, H93366, Hs 7567, branched chain aminotransferase 1, cytosolic, branched chain aminotransferase 1, cytos, 11 42
414812, X72755 Hs 77367, monokine induced by gamma interferon, monokine induced by gamma interferon, 11 38
421917, AB028943, Hs 109445 KIAA1020 protein, KIAA1020 protein, 11 15 440006 AK000517, Hs 6844, NALP2 protein, PYRIN-Containing APAFMike, NALP2 protein, PYRIN-Containing APAF1-lι, 1092
414683, S78296, Hs 76888, hypothetical protein MGC12702, hypothetical protein MGC12702, 1091
423673, BE003054, Hε 1695, matrix metalloproteinaεe 12 (macrophage elastase), matnx metalloprotemase 12 (mxrophage , 1074
433800, AI034361, Hs 135150, lung type-l cell membrane-assxiated glycoprotein, lung type-l cell membrane-asεxiated gly, 1068
429120, AK001673, Hs 196530, hypothetical protein FLJ10811, hypothetical protein FLJ10811, 1048 444371, BE540274, Hs 239, forkhead box M1, forkhead box M1, 1046
441553, AA281219, Hs 121296, ESTs, ESTs, 1037
426534, U58096, Hs 2051, testis spxific protein, Y-lmked, testis spxific protein, Y-lmked, 1028
441878, AI801869, Hs 127982, ESTs, ESTs, 1006
432117, AL036195, Hs 2909, protamine 1 , protamine 1, 1001 425427, AI652662, Hs 317432, branched chain aminotransferase 1, cytosolic, branched chain aminotransferase 1 , cytos, 997
416201, AA467752, Hs 195161, ESTs, ESTs, 997
410929, H47233, Hs 30643, ESTs, ESTs, 991
427486, AA974433, Hs 362432, fibroblast growth fxtor 4 (hepaππ sxretory transforming protein 1, Kaposi sarcoma oncogene), fibroblast growth fxtor 4 (hepaπn sxr, 981
427239, BE270447, Hs 356512, ubiquitin earner protein, ubiquitin earner protein, 968 402680, , , Target Exon, Target Exon, 968
409208, Y00093, Hs 172631, integnn alpha X (antigen CD11C (p150), alpha polypeptide), integnn, alpha X (antigen CD11C (p150)„ 946
443426, AF098158, Hs 9329, chromosome 20 open reading frame 1, chromosome 20 open reading frame 1, 942
440207, AI371978, Hs 128326, ESTs, ESTε, 941
433001, AF217513, Hε 279905, clone HQ0310 PRO0310p1, clone HQ0310 PRO0310p1, 941 447534, AW953935, Hs 288655, ESTs, ESTs, 933
442333, AI650877, Hs 129302, ESTs, ESTs, 928
421307, BE539976, Hs 103305, Homo sapiens mRNA, cDNA DKFZp434B0425 (from clone DKFZp434B0425), Homo sapiens mRNA, cDNA DKFZp434B0425 (f, 924
423458, AI204212, Hs 351113, ESTs, ESTs, 923
431958, X63629, Hs 2877, cadhenn 3, type 1, P-cadheπn (plxental), cadhenn 3, type 1, P-cadheπn (plxenta, 923 422938, NM.001809, Hs 1594, centromere protein A (17kD), centromere protein A (17kD), 921
411027, AF072099, Hs 67846, leukxyte immunogfobulin-like rxeptor, subfamily B (with TM and ITIM domains), member 4, leukxyte immunoglobulm-like rxeptor, , 9 21
425397, J04088, Hs 156346, topoisomerase (DNA) II alpha (170kD), topoisomerase (DNA) II alpha (170kD), 9 18
428664, AK001666, Hs 189095, similarto SALL1 (sal (Droεophιla)-lιke, similar to SALL1 (sal (Drosophιla)-lιke, 9 17
428970, BE276891, Hs 194691, retinoic xid induced 3 (RAIG1), metabotropic glutamate family GPCR retinoic xid induced 3(RAIG1), eiabo, 9 11 447733, AF157482, Hs 19400, MAD2 (mitotic arrest deficient, yeast, homolog) like 2, MAD2 (mitotic arrest deficient, yeast, h, 9 11
422310, AA316622, Hs 98370, cytxhrome P450, subfamily IIS, polypeptide 1, cytxhrome P450, subfamily IIS, polypept, 9 10 449722, BE280074, Hs 23960, cyclin B1, cyclin B1, 886
441560, F13386, Hs 7888, v-erb-a avian erythroblastic leukemia viral oncogene homolog like 4 (HER4), v-erb-a avian erythroblastic leukemia vi, 886 440983, M20681, Hs 7594, solute earner family 2 (facilitated glucose transporter), member 3, solute earner family 2 (facilitated glu, 886 409342, AU077058, Hs 54089, BRCA1 asεxiated RING domain 1 , BRCA1 aεε∞iated RING domain 1 , 883
420367, AA259090, Hε 257028, ESTε, ESTs, 882
415947, U04045, Hs 78934, mutS (E coli) homolog 2 (colon cancer, nonpolyposis type 1), mutS (E coli) homolog 2 (colon cancer, , 873
418613, AA744529, Hs 86575 mitogen-activated protein kinase kinase kinase kinase 1, mitogen xtivated protein kinase kinase , 871 417407, AA923278, Hs 290905, ESTs, Weakly similar to protease [H sapiens], ESTs, Weakly similar to protease [H sapi, 864
407239, AA076350, Hs 67846, leukxyte immunoglobulin like receptor, subfamily B (with TM and ITIM domains), member 4, leukxyte immunoglobulin like receptor 8 58 436481, AA379597, Hs 5199, HSPC150 protein similar to ubiquitiπ-conjugatiπg enzyme, HSPC150 protein similar to ubiquit -con, 855 412140, AA219691, Hs 73625, RAB6 interacting, kinesm like (rabkinesin 6), RAB6 interacting kinesm like (rabkmes, 852 5 438091, AW373062, Hs 351546, nuclear rxeptor subfamily 1, group I, member 3 nuclear receptor subfamily 1, group I, m 851
424800, AL035588, Hs 153203, MyoD family inhibitor, MyoD family inhibitor; 845 447188, H65423, Hs 17631, hypothetical protein DKFZp434E2135, hypothetical protein DKFZp434E2135, 845 430056, X97548, Hs 228059, KRAB-assxiated protein 1, KRAB associated protein 1, 842
417389, BE260964, Hs 82045, midkme (πeuπte growth promoting factor 2), midkme (neuπte growth promoting factor; 840 0 430676 AF084866, Hs 372585, gb Homo sapiens envelope protein RIC-3 (env) gene, complete ed gb Homo sapiens envelope protein RIC-3 (, 8 38
420759, T11832, Hs 127797, Homo sapiens cDNA FLJ11381 fis, clone HEMBA1000501, Homo sapiens cDNA FLJ11381 fis, clone HE, 838 406621, X57809, Hs 181125, immunoglobulin lambda Ixus, immunoglobulin lambda Ixus, 837 453914, NM_000507, Hs 574, fructose-1,6 biεphoεphatase 1, fructose-1,6-bιsphosphatase 1, 825 423198, M81933, Hs 1634, cell division cycle 25A, ceil division cycle 25A, 8 19 5 418299, AA279530, Hs 83968, integnn, beta 2 (antigen CD18 (p95), lymphxyte function-assxiated antigen 1, macrophage antigen 1 (mac-1) beta subunit), integnn beta 2 (antigen
CD18 (p95), ly, 8 17 453968, AA847843, Hs 62711, High mobility group (nonhistone chromosomal) protein 4, High mobility group (nonhistone chromoεo, 8 16 453985, N44545, Hs 251865, ESTs, ESTs, 8 14 451106, BE382701, Hs 25960, N-MYC oncogene, N-MYC oncogene, 8 10 0 420347, AL033539, Hs 97124, Human DNA sequence from clone RP1-309H15 on chromoεome 6p22 1-223 Coπtainε a gene similarto HDGF (hepatoma-denved growth fxtor (high mobility group protein 1-lιke)), ESTs, STSs, GSSs and a CpG Isl, Human DNA sequence from clone RP1-309H15, 803 415857, AA866115, Hs 127797, Homo sapiens cDNA FLJ11381 fis, clone HEMBA1000501, Homo sapiens cDNA FLJ11381 fis, clone HE, 802 425601, AW629485, Hs 140720, GSK-3 binding protein FRAT2, GSK-3 binding protein FRAT2, 7 90
421016, AA504583, Hs 101047, transcnption factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), transcnption fxtor 3 (E2A i munoglobul, 7 89 5 432407, AA221036, , gb zr03f12 rl Stratagene NT2 neuronal prxursor 937230 Homo sapienε cDNA clone 5' similarto SW POL_BAEVM P10272 POL POLYPROTEIN „ mRNA sequence, gb zr03f12 r1 Stratagene NT2 neuronal pr; 7 83 422846, BE513934, Hs 1583, neutrophil cytosolic fxtor 1 (47kD, chronic granulomatous disease, autoεomal 1), neutrophil cytosolic factor 1 (47kD, chr, 7 80 433228, F28212, Hs 14953, KIAA1491 protein, KIAA1491 protein, 773 446528, AU076640, Hs 15243, nucleolar protein 1 (120kD), nucleolar protein 1 (120kD), 771 447350, AI375572, Hs 172634, v-erb-a avian erythroblastic leukemia viral oncogene homolog like 4 (HER4), v-erb-a avian erythroblastic leukemia vi 771
448775 AB025237, Hs 388 πudix (nucleoside diphosphate linked moiety X) type motif 1, nudix (nucleoside diphosphate linked oi, 771 430253, AK001514 Hs 236844, hypothetical protein FU10652, hypothetical protein FLJ10652, 7 70
444784 D12485, Hs 11951, ectonucl∞tide pyrophosphatase/phosphodiesterase 1 (Plasma-cell membrane glycoprotein PC-1), xtonudeotide pyrophosphatase/phosphodi, 762 443537, D13305, Hs 203, cholecystokmin B rxeptor, cholecystokinm B rxeptor, 757 5 446291, BE397753, Hs 14623, interferon, gamma inducible protein 30, interferon, gamma-inducible protein 30, 7 55
410006 AW732308, Hs 57783, eukaryotic translation initiation fxtor 3, subunit 9 (eta, 116kD), eukaryotic translation initiation factor; 753 430255, AK00O7O3, Hs 323822, Homo sapiens mRNA for KIAA1551 protein, partial eds, Homo sapienε mRNA for KIAA1551 protein, , 752 411975, AI916058, Hs 144583, 3'UTR of dead nnger (Drosophila) like 1, 3 UTR of dead ringer (Drosophila) like , 7 50
439864, AI720078, Hs 291997, ESTs, Weakly similar to A47582 B-cell growth fxtor prxursor [H sapiens], ESTs, Weakly similar to A47582 B-cell gr, 747 0 440773, AA352702, Hs 37747, Homo sapiens, Similar to RIKEN cDNA 2700083B06 gene, clone MGC 4669, mRNA, complete eds, Homo sapiens, Similar to RIKEN cONA 2700 747
417705, AW134952, Hs 175220, hypothetical protein FLJ14541, hypothetical protein FLJ14541, 747
425367, BE271188, Hs 155975, protein tyrosine phosphatase, rxeptor type, C-assxiated protein, protein tyrosine phosphatase, receptor t, 747 407710, AW022727, Hs 23616, ESTs, ESTs, 745 445093, AI207197, Hs 374149, ESTε, ESTε, 7 41 5 418113, AI272141, Hs 83484, SRY (sex determining region Y)-box 4, SRY (sex determining region Y)-box 4, 739
417900, BE250127, Hs 82906, CDC20 (cell division cycle 20, S cerevisiae, homolog), CDC20 (cell division cycle 20, S cerevi, 7 37
429469, M64590, Hs 111801, glycine dehydrogenase (dxarboxylating, glycine d∞arboxylase, glyc e cleavage system protein P), glycine dehydrogenase (dxarboxylatmg, , 733 422726, U11690, Hs 1572, faciogemtal dysplaεia (Aarεkog-Scott εyndrome), fxiogenital dysplasia (Aarskog-Scott sy, 733 430504, H52761, Hs 44095, Homo sapienε, clone MGC 12617, mRNA, complete cdε, Homo εapieπs, clone MGC 12617, mRNA, com, 732 0 448981, AI968719, Hs 195387, ESTs, ESTs, 728
413762, AW411479, Hs 848, FK506-bιndιng protein 4 (59kD), FK506-bιndιng protein 4 (59kD), 726
435092, AL137310, Hs 4749, Homo sapienε mRNA, cDNA DKFZp761E13121 (from clone DKFZp761E13121), partial eds, Homo sapienε mRNA cDNA DKFZp761E13121 ( 7 25 434414, AI798376, , gb tr34b07 x1 NCI_CGAP_Ov23 Homo sapiens cDNA clone 3' similar to TR 015475 015475 UNNAMED HERV-H PROTEIN „ mRNA sequence, gb tr34b07 x1 NCI_CGAP_0v23 Homo sapiens, 724 5 428977, AK001404, Hs 194698, cyclin B2, cyclin B2, 7 19
434274, AA628539, Hs 57783, ESTs, Moderately similar to ALU1 HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens], ESTs, Moderately similarto ALULHUMAN A, 7 19 446700, AW206257, Hs 156326, Human DNA sequence from clone RP11-145L22 on chromosome 6p21 32-222 Contains the gene formyeliπ/oligodeπdrocyte glycoprotein MOG, (part of) the gene for a novel KRAB box containing C2H2 type zinc f, Human DNA sequence from clone RP11-145L2, 7 16 0 420524, AB010575, Hs 98547, amiloπde-sensitive cation channel 3, testis, amiloπde-sensitive cation channel 3, te, 715
439053, BE244588, Hs 6456, chaperonin containing TCP1, εubuπit 2 (beta), chaperonin containing TCP1, subunit 2 (b, 7 14 445076, A1206888, Hs 154131, ESTs ESTs, 7 14 448588, AI970276, Hs 156905, KIAA1676, KIAA1676, 7 13
429486, AF155827, Hs 203963, hypothetical protein FU10339, hypothetical protein FU10339, 7 10 5 441362, BE614410, Hs 23044, RAD51 (S cerevisiae) homolog (E coli RxA homolog), RAD51 (S cerevisiae) homolog (E coli Re, 704
433914, AF108138, Hs 112160, Homo sapiens DNA helicase homolog (PIF1) mRNA, partial eds, Homo sapienε DNA helicaεe homolog (PIF1), 702 413278, BE563085, Hε 833, interferon stimulated protein, 15 kDa, interferon-stimulated protein, 15 kDa, 702
423765, R23858, Hs 143375, Homo sapiens, clone IMAGE 3840937, mRNA, partial eds, Homo sapiens, clone IMAGE 3840937, mRNA,, 696 416658, U03272, Hs 79432, fibπlliπ 2 (congenital contrxtural arxhπodactyly), fibπllin 2 (congenital contrxtural ara, 692 0 438450, A1050866, Hs 65853, nodal, mouse, homolog, nodal, mouse, homolog, 690
415323, BE269352, Hs 949, neutrophil cytosolic fxtor 2 (65kD, chronic granulomatous disease, autosomal 2), neutrophil cytosolic fxtor 2 (65kD, chr, 690 444381, BE387335, Hs 283713, hypothetical protein BC014245, hypothetical protein BC014245 689 447582, BE293520, Hs 18910, prostate cancer overexpresεed gene 1, prostate cancer overexpresεed gene 1, 689 424779, AL046851 , Hε 153053, CD37 antigen, CD37 antigen, 689 /-> 443907, AU076484, Hε 9963, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase binding pro, 684
427298, AA400495, , ESTs, ESTs, 682
414732, AW410976, Hs 77152, minichromosome maintenance deficient (S cerevisiae) 7, minichromosome maintenance deficient (S , 681 424959, NM.005781, Hs 153937, activated p21cdc42Hs kinase, activated p21cdc42Hs kinase, 681 426866, U02330, Hs 172816, neuregul 1, neuregulin 1, 680 80 418203, X54942, Hs 83758, CDC28 protein kinase 2 CDC28 protein kinase 2, 680
427521, AW973352, , ESTs, ESTs, 675
430397, AI924533, Hε 105607, bicarbonate transporter related protein 1, bicarbonate transporter related protein , 675 427719, AI393122, Hs 134726, ESTs, ESTs, 674 439453 BE264974 Hs 6566, thyroid hormone rxeptor mterxtor 13 thyroid hormone rxeptor mterxtor 13, 672 453348 BE272318 Hs 8595, hypothetical protein FLJ12438, hypothetical protem FLJ12438, 671
446113, AW967553 Hs 323518, Homo sapiens mRNA for FLJ00083 protein, partial eds, Homo sapiens mRNA for FLJ00083 protein , 670 445363, NM 005993 Hs 12570, tubulin-spxific chaperone d, tubulin spxific chaperone d, 670 433701 , AW445023 Hs 15155, ESTs, ESTs, 669
418054, NM.002318 Hs 83354, lysyl oxidase like 2, lysyl oxidase like 2, 663 441031 AH 10684, Hs 7645, fibrinogen, B beta polypeptide fibnnogen, B beta polypeptide, 662
439237, AW408158 Hs 318893 ESTs, Weakly similar to A47582 B cell growth fxtor prxursor (H sapiens], ESTs, Weakly similar to A47582 B-cell gπ 659 424381, AA285249 Hs 146329, protein kinase Chk2 (CHEK2) protein kinase Chk2 (CHEK2), 658 414821, M63835, Hs 77424, Fc fragment of IgG, high affinity la receptor for (CD64), Fc fragment of IgG, high affinity la re 658
418883, BE387036 Hs 1211, acid phoεphataεe 5, tartrate resistant, xid phosphatase 5, tartrate resiεtaπt 657 414161, AA136106 Hs 184852, KIAA1553 protein, KIAA1553 protein, 6 57
437437, AA226869, Hs 351623, hypothetical protein DKFZp762L0311, hypothetical protein DKFZp762L0311, 655 425769, U72513, Hs 159486, Human RPL13-2 pseudogene mRNA, complete eds, Human RPL13-2 pseudogene mRNA, complete , 655 452363, AI582743 Hs 94953, Homo sapiens, Similar to complement component 1, q subcomponent, c polypeptide, clone MGC 17279, mRNA, complete eds, Homo sapiens, Similar to complement comp, 655 422765, AW409701, Hs 1578, bxuloviral IAP repeat-containing 5 (survivin), bxuloviral IAP repeat-oontaiπing 5 (sun 651 409893, AW247090 Hs 57101, minichromosome maintenance deficient (S cerevisiae) 2 (mitotin), minichromosome maintenance deficient (S , 650 418918, X07871, Hs 89476, CD2 antigen (p50), sheep red blood cell rxeptor, CD2 antigen (p50), sheep red blood cell , 649 417911, AA333387, Hs 82916, chaperonin containing TCP1 , subunit 6A (zeta 1), chaperonin containing TCP1, subunit 6A (, 644
427747, AW411425 Hs 180655, seπne/threonme kinase 12, seπne/threonme kinase 12, 643
409142, AL136877, Hs 50758, SMC4 (structural maintenance of chromosomes 4, yeast)-lιke 1, SMC4 (structural maintenance of chromoso, 642 430280, AA361258, Hs 237868, interleukin 7 receptoπ interleukin 7 rxeptor, 642 432938, T27013, Hs 3132, steroidogenic acute regulatory protein, steroidαgeπic xute regulatory protein, 642 422809, AK001379 Hs 121028, hypothetical protein FLJ10549, hypothetical protein FLJ10549, 640
427578 AI591305 Hs 169084, ESTs, Highly similar to TUL3.HUMAN TUBBY RELATED PROTEIN 3 [H sapiens], ESTs, Highly similar to TUL3.HUMAN TUBBY, 640 417115, AW952792, Hs 334612, small nuclear nbonucleoprotein polypeptide E, small nuclear πbonuclxprotem polypept, 639 428227, AA321649, Hs 2248, small inducible cytokine subfamily B (Cys-X-Cyε), member 10, εmall inducible cytokine subfamily B (Cy, 639 441384, AA447849, Hs 288660, retinoic xid induced 3, retinoic xid induced 3, 6 38 438915, AA280174, Hs 285681, Williams-Beuren syndrome chromosome region 14, Williams-Beuren εyndrome chromoεome regi, 634
416773, AK000340, Hs 79828, hypothetical protem FLJ20333, hypothetical protein FLJ20333, 634
451999, AW176401, Hε 27424, DEAD/H (Aεp-Glu Ala Asp/His) box polypeptide 11 (S cerevisiae CHL1-lιke helicase), DEAD/H (Asp-Glu Ala-Asp/His) box polypep, 631 444159, AF116846, Hs 10431, dead ππger(Drosophιla)-lιke 2 (bπght and dead ππger), dead ringer (Drosophιla)-lιke 2 (bright , 631 425274, BE281191, Hs 155462, minichromosome maintenance deficient (mιs5, S pombe) 6 minichromosome maintenance deficient (mi, 631 434649, AA738254, Hs 165390, ESTs, Highly similar to A40350 transcription repreεεor protein YY1 [H εapienε], ESTs Highly similar to A40350 transcπp, 630
420507, AF093408, Hs 98397, A kinase (PRKA) anchor protein 3, A kinase (PRKA) anchor protein 3, 630 415829, AW450198, Hs 163742, ESTs, ESTs, 628
410342, R31350, Hs 743, Fc fragment of IgE, high affinity I, receptor for, gamma polypeptide, Fc fragment of IgE, high affinity I, rx, 626 446839, BE091926, Hs 16244, mitotic spindle coiled-coil related protein, mitotic spindle coiled coil related prot, 6 25 457465 AW301344 Hs 122908, DNA replication fxtor; DNA replication fxtor; 625
428918, AL036967, Hs 2324, protamine 2, protamine 2, 6 24
443523, AK001575, Hs 9536, hypothetical protein FLJ10713, hypothetical protein FLJ10713, 6 19 424415, NM_001975, Hs 146580, enolase 2, (gamma, neuronal), enolaεe 2, (gamma neuronal), 6 19 407245, X90568, Hε 172004, titin, titin, 6 18 458627, AW088642 Hs 97984, SRY (sex determining region Y) box 17 (SOX17), SRY (sex determining region Y) box 17 (S, 6 18
421379, Y15221, Hs 103982, small inducible cytokine subfamily B (Cys-X Cys), member 11, small inducible cytokine εubfamily B (Cy, 6 16 435099, AC004770, Hs 4756, flap structure-εpecific endonuclease 1, flap slruclure spxific eπdoπucleaεe 1, 6 13 424308, AW975531, Hs 154443, minichromosome maintenance deficient (S cerevisiae) 4, minichromosome maintenance deficient (S , 6 12 430521, NM.016383, Hs 242183, HOM-TES-85 tumor antigen, HOM-TES 85 tumor antigen, 6 10 444823, BE262989, Hs 12045, putative protein, putative protein, 6 10
428484, AF104032, Hs 184601, solute earner family 7 (cationic am o xid transporter, y syεtem), member 5, εolute earner family 7 (cationic ammo , 609 402260, , , NM.001436* Homo εapiens fibπllaππ (FBL), mRNA transcnpt) (F8A), mRNA , NM.001436* Homo sapiens fibπllaπn (FBL, 609
441321, H17182, Hs 7771, B-cell assxiated protein, B-cell asεxiated protein, 605
422283, AW411307, Hs 114311, CDC45 (cell diviεion cycle 45, S cerevisiae, homolog) like, CDC45 (cell division cycle 45, S cerevis, 604 431629, AU077025, Hs 265827, interferon, alpha-inducible protein (clone IFI-6-16), interferon, alpha-inducible protein (clo, 604
402678, , , Target Exon, Target Exon, 603
453884, AA355925, Hs 36232, KIAA0186 gene product, KIAA0186 gene product, 601
439753, BE262233 Hs 7423, hypothetical protein from EUROIMAGE 2168212, hypothetical protein from EUROIMAGE 2168, 601 420596, NM.002692, Hs 99185, polymerase (DNA directed), epsilon 2, polymerase (DNA dirxted), epsilon 2, 601 420676, AI434780, Hs 4248, vav 2 oncogene, vav 2 oncogene, 600
418756 AA252254, Hs 226949, ESTs, ESTs, 599 454438, AA224053, Hs 172405, cell division cycle 27, cell division cycle 27, 598 407818, AL021938, Hs 40154, jumonji (mouse) homolog, ju oπji (mouse) homolog, 598 413313, NM.002047, Hε 293885, glycyl-tRNA εynthetase, glycyl tRNA synthetaεe, 596 424247, X14008, Hε 234734, iyεozyme (renal a yloidosiε), lysozyme (renal amylσidosiε), 595
417777, AI823763, Hε 7055, ESTε, Weakly similar to I78885 seππe/threonme-εpxific protein kinaεe [H sapiens], ESTs, Weakly similar to I78885 seπne/th, 594 449569, AI656634, Hs 195389, ESTs, ESTs, 592 436576, AI458213, Hs 77542, ESTs, ESTs, 590
438746, AI885815, Hs 184727, Human melanoma-assxiated antigen p97 (melanolranεferπn) mRNA, 3' flank, Human melanoma-aεε∞iated antigen p97 (m, 589 420005, AW271106 Hs 133294, ESTs, ESTs, 589
417208, S67773, Hs 81665, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy-Zuckerman 4 feline εarcoma v, 588 403171, , , C2001472* gι|5809678|gb|AAB418482| (U64675) sperm membrane protein BS 63 [Homo sapiens]]!, C2001472* gι|5809678|gb|AAB41848 2| (U64, 587 448730, AB032983, Hs 21894, KIAA1157 protein, KIAA1157 protein, 587
406137, , , NM.000179* Homo sapienε mutS (E coli) homolog 6 (MSH6), mRNA VERSION NM.000178 1 Gl, NM.000179* Homo εapiens mutS (E coli) h, 585 423787, AJ295745, Hs 236204, nuclear pore complex protein, nuclear pore complex protein, 5 85
425126, N32759, Hs 172944, chorionic gonadotropin, beta polypeptide, choπonic gonadotropm, beta polypeptide, 584 452796, AB011100 Hs 30656, KIAA0528 gene product, KIAA0528 gene product, 584
418322, AA284166, Hs 84113, cyclm-dependent kinase inhibitor 3 (CDK2 assxiated dual specificity phosphatase), cyclm-dependent kinase inhibitor 3 (CDK, 580 447359, NM.012093, Hs 18268, adenylate kinase 5, adeπylate kinase 5, 579 420344, BE463721, Hs 97101, putative G protein-coupled rxeptor, putative G protein-coupled receptor, 578
420297, AI628272 Hs 128757, ESTs, Weakly similar to ALU1 HUMAN ALU SUBFAMILY J SEQUENCE CONTAMINATION WARNING ENTRY [H sapieπε], ESTs, Weakly similar to
ALULHUMAN ALU S, 575 414761, AU077228, Hs 77256, enhancer of zeste (Drosophila) homolog 2, enhancer of zeste (Drosophila) homolog 2, 575 430287, AW182459, Hs 125759, ESTs, Weakly similar to LEU5.HUMAN LEUKEMIA ASSOCIATED PROTEIN 5 |H sapiens], ESTs, Weakly similar to LEU5.HUMAN LEUKE, 574 436251, BE515065, Hs 296585, nucleolar protein (KKE/D repeat), nucleolar protein (KKE/D repeat), 573
421535, AB002359, Hs 105478, phosphoπbosylformylglyciπa idiπe εyπlhase (FGAR amidolraπsferase), phosphσribosylformylglycinamidine syntha, 571 414883, AA926960, Hs 348669, CDC28 protein kmase 1, CDC28 protein kinase 1, 569 425159, NM 004341, Hs 154868, carbamoyl phosphate synthetase 2, aspartate transcarbamylase and dihydroorotase, carbamoyl phosphate εynthetaεe 2, aspart 569
401704, , , NM.021195* Homo sapienε claudin 6 (CLDN6) mRNA VERSION NM.020982 1 Gl, NM.021195* Homo εapienε claudin 6 (CLDN6 566 425358, AL079~658, Hε 338207, FK506 binding protein 12 rapamycm associated protein 1, FK506 binding protein 12-rapamycm assoc, 5 65
402677, , , NM.000478 Homo sapiens alkaline phosphatase, liverbone/kidney (ALPL), mRNA. alpha hydroxylase), polypeptide 1 (CYP7B1), mRNA., NM.000478 Homo sapienε alkaline phoεphat, 564 0 409264, NM.014937, Hε 52463, KIAA0966 protein, KIAA0966 protein, 563
432185, AA221032, Hs 272838, hypothetical protein FLJ10494, hypothetical protein FLJ10494, 563 409012 AL117435, Hs 49725, DKFZP434I216 protein, DKFZP434I216 protein, 563
430252, AI638774, Hs 105328, testes development related NYD-SP20, testes development-related NYD SP20 561 419359, AL043202, Hs 90073, chromosome segregation 1 (yeast homolog) like, chromosome segregation 1 (yeast homolog), 561 5 452816, AA131789, Hs 61509, ESTs, ESTs, 560
402679, , , NM_000478 Homo sapiens alkaline phosphataεe, liver/bone/kidney (ALPL) mRNA alpha hydroxylase), polypeptide 1 (CYP7B1), mRNA , NM.000478 Homo sapiens alkaline phosphat, 559 414291, AI289619, Hs 13040, G protein-coupled receptor 86, G protem-coupled receptor 86, 5 58 453028, AB006532, Hs 31442, RecQ protein-like 4, RecQ protein like 4, 558 0 453905, NM.002314, Hs 36566 UM domain kinase 1, LIM domain kinase 1, 556
411263, BE297802, Hs 69360, kinesm like 6 (mitotic centromere associated kinesm), kinesiπ like 6 (mitotic centromere ass∞, 555 419660, BE280337, Hε 194693, solute camerfamily 7 (cationic am o xid transporter, y system), member 7, solute camerfamily 7 (cationic am o , 5 55 446979, AI654443, Hs 197683, ESTs, ESTs, 554
424321, W74048, Hs 1765, lymphxyte-spxific protein tyrosine kinase, lymphxyte-spxific protein tyrosine k , 553 5 418962, AA714835, Hs 271863, ESTs, ESTs, 553
447388, AW630534, Hs 76277, Homo sapiens, clone MGC 9381, mRNA, complete eds, Homo sapienε, clone MGC 9381, mRNA, comp, 552
427247, AW504221, Hs 174103, integπn, alpha L (antigen CD11A (p180), lymphxyte function-asεxiated antigen 1, alpha polypeptide), mtegnπ, alpha L (antigen CD11A (p180)„
552 449322, AI638616, Hε 196566, ESTε, ESTε, 5 51 0 428450, NM 014791, Hs 184339, KIAA0175geπe product, KIAA0175geπe product, 551
415141, AA189099, Hs 268171, ESTs, Weakly similarto ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY [H εapiens], ESTs, Weakly similar to ALU7 HUMAN ALU S, 548 454048, H05626, Hs 6921, ESTs, ESTs, 546
417079, U65590, Hs 81134, interleukin 1 rxeptor antagonist interleukin 1 receptor antagonist, 545 5 434699, AA643687, Hs 149425, Homo εapieπε cDNA FLJ11980 fiε, clone HEMBB1001304, Homo εapienε cDNA FU11980 fis, clone HE, 544
414334, AA824298, Hs 21331, hypothetical protein FLJ10036, hypothetical protein FLJ10036, 544
452291, AF015592, Hs 28853, CDC7 (cell division cycle 7, S cerevisiae, homolog) like 1, CDC7 (cell division cycle 7, S cerevisi, 544 438564, AA381553, Hs 198253, major histxompatibility complex, class II, DQ alpha 1, major histxompatibility complex, class , 544 427668, AA298760, Hs 180191, hypothetical protein FLJ14904, hypothetical protein FLJ14904, 543 0 449437, AI702038, Hs 100057, Homo sapiens cDNA FLJ22902 fis, clone KAT05581, Homo sapiens cDNA FLJ22902fis, clone K, 541
453633, AA357001, Hs 34045, hypothetical protein FLJ20764, hypothetical protein FLJ20764, 540 450746, D82673, Hs 278589, general transcnption fxtor II, i, general transcnption fxtor II, i, 540 425966, NM.001761, Hs 1973, cyclin F, cyclin F, 539 418134, AA397769, Hs 86617, ESTs, ESTs, 538 5 432141, BE410964, Hs 272736, nuclear rxeptor binding protein, nuclear rxeptor binding protein, 537
417141, U22662, Hε 347353, nuclear rxeptor subfamily 1, group H, member 3, nuclear rxeptor subfamily 1 , group H, m, 536
428329, AA426091, Hs 98453, ESTs, Moderately similar to R273282 [H sapienε] ESTs, Moderately similar to R273282 [H , 535
406811 , U82979, Hε 67846, leukxyte immunoglobulin like rxeptor, εubfamily B (with TM and ITIM domainε), member 4, leukxyte immunoglobulin like rxeptor, , 534
415819, AU077330, Hε 360791, tranεcπption elongation fxtor A (SH), 1, tranεcπption elongation factor A (Sll)„ 533 O 448133, AA723157, Hs 73769, folate rxeptor 1 (adult), folate rxeptor 1 (adult), 533
424762, AL119442, Hs 183684, eukaryotic translation initiation fxtor 4 gamma, 2, eukaryotic translation initiation fxtor, 532
421959, AW751497, Hs 98370, cytxhrome P450, subfamily IIS, polypeptide 1, cytxhrome P450, subfamily IIS, polypept, 532
429271, AF039850, Hε 198515, dead πnger (Drosophila) like 1, dead πnger (Drosophιla)-lιke 1, 532
456373, BE247706, Hs 86693, membrane spanning 4-domaιπs, subfamily A, member 2 (CD20 antigen), membrane εpanπing 4-domaιns, subfamily A, 530 414907, X90725, Hs 77597, polo (Drosophιa)-lιke kmase, polo (Drosophιa)-lιke kinase, 530
422997, BE018212, Hs 122908, DNA replication fxtor, DNA replication fxtor, 529
440014, AW960782, Hs 6856, asfι2 (absent, small, or homeotic, Drosophila, homolog)-lιke, ash2 (absent, small, or hom∞tic, Drosop, 528
418399, AF131781, Hs 84753, hypothetical protein FLJ12442, hypothetical protein FLJ12442, 5 26
416178, AI808527, Hs 192822, εerologically defined breaεt cancer antigen NY-BR 81 , serologically defined breast cancer anti, 521 0 450377, AB033091, Hs 355925, KIAA1265 protein, KIAA1265 protein, 520
409670, AI368109, Hε 375604, KIAA1856 protein, KIAA1856 protein, 520
429083, Y09397, Hε 227817, BCL2-related protein A1, BCL2-related protein A1, 520
449523, NM.000579, Hε 54443, chemokine (C-C motif) rxeptor 5, chemokine (C-C motif) rxeptor 5, 520
408908, BE296227, Hε 250822, εeπne/threonine kinase 15, seππe/threonine kinase 15, 5 19 5 429732, U20158, Hs 2488, lymphxyte cytosolic protein 2 (SH2 domain-containing leukxyte prote of 76kD), lymphxyte cytosolic protein 2 (SH2 doma 5 19
438089, W05391, Hs 351546, nuclear rxeptor subfamily 1, group I, member 3, nuclear rxeptor subfamily 1, group I, , 5 16 437623, D63880, Hs 5719, chromosome condensation-related SMC-asεxiated protein 1, chromoεome condenεafion-related SMC-aεso, 5 15 448181, AF272833, Hs 279763, hypothetical protein FU10504, hypothetical protein FLJ10504, 515 436540, BE397032, Hs 14468, hypothetical protein MGC14226, hypothetical protein MGC14226, 5 14 0 422241, Y00062, Hs 170121, protein tyrosine phosphatase, rxeptor type, C, protein tyrosine phosphatase, rxeptor t, 5 14 426752, X69490, Hs 172004, titin, titin, 513
415007, BE244332, Hs 77770, adaptor-related protein complex 3, mu 2 subunit; adaptor-related protein complex 3, mu 2 , 513 400263, , Hs 75309, Eos Control, Eos Control, 5 13 437099, N77793, Hs 48659, ESTs, Highly similar to S14458 laminin alpha-1 chain prxursor [H sapienε], ESTε, Highly simitar to S14458 laminin a, 5 12
75 427209, H06509, Hs 92423, KIAA1566 protein, KIAA1566 protein 5 10
407347, AA829847, , gb od40d07 s1 NCI.CGAP.GCB1 Homo εapiens cDNA clone IMAGE 13704133' similar to contains Alu repetitive element , mRNA sequence , gb od40d07 s1
NCI.CGAP.GCB1 Homo sapiens, 5 10 458933, AI638429, Hs 24763, RAN binding protein 1, RAN binding protein 1, 5 10 450431, AW136797, Hs 266041, ESTs, ESTs, 509 O O 434608, AA805443, Hs 179909, hypothetical protein FLJ22995, hypothetical protein FLJ22995, 508
410423, AW402432, Hε 63489, protein tyrosine phosphatase, non receptor type 6, protein tyrosine phosphatase, non rxept, 508
417929, R27219, Hs 74647, Human T-cell rxeptor xtive alpha-chain mRNA from JM cell line, complete eds, Human T-cell receptor active alpha-chain, 505
412723, AA648459, Hs 335951, hypothetical protein AF301222, hypothetical protein AF301222, 505 447321, AW271217, Hs 281434, Homo sapiens cDNA FLJ14028 fis, clone HEMBA1003838, Homo sapienε cDNA FLJ14028 fis clone HE, 503 417866 AW067903, Hs 82772, collagen, type XI, alpha 1, collagen, type XI, alpha 1, 503 410082, AA081594, Hs 158311, Musaεhi (Droεophila) homolog 1, Muεashi (Drosophila) homolog 1, 502 433592 NM.004642, Hs 3436 deleted in oral cancer (mouse, homolog) 1, deleted in oral cancer (mouse homolog) , 502 5 425811, AL039104, Hs 159557, karyophenn alpha 2 (RAG cohort 1, importin alpha 1), karyophenn alpha 2 (RAG cohort 1, impor, 500
425237, U07695, Hs 155227, EphB4, EphB4, 500
414809, AI434699, Hs 77356, transfemn receptor (p90 CD71), transferrin rxeptor (p90, CD71), 499 402145, , , Target Exon, Target Exon, 499 432126 AA865239, Hs 37196, ESTs ESTε, 499 0 408279, AF216965, Hs 44095 Homo sapiens, clone MGC 12617, mRNA, complete eds, Homo sapiens, clone MGC 12617, mRNA, com, 498
419525, T79257, Hs 1259, asialoglycoprotein receptor 2 asialoglycoproteiπ rxeptor 2, 497 424439, AA579635, Hs 1770, ligase I, DNA, ATP-dependent, ligase I, DNA ATP-dependent, 497
427667, AK001279, Hs 180171, Homo sapienε cDNA FLJ10417 fiε, clone NT2RP1000112 Homo εapienε cDNA FLJ10417 fis, clone NT, 496 457313 AF047002, Hs 241520, transcπptional coxtivator, transcπptional coxtivator, 496 5 448569 BE382657, Hs 21486, signal transducer and xtivator of transcnption 1 , 91kD, signal transducer and xtivator of trans, 494
426427, M86699, Hs 169840, TTK protein kinase, TTK protein kinase 491
440129, AA865818, Hs 369523, ESTs, Weakly similar to S71886 Ste20 like protein kinase [H sapiens], ESTs, Weakly similar to S71886 Ste20 Ilk, 491 453922, AF053306, Hs 36708, budding uninhibited by benzimidazoles 1 (yeast homolog), beta, budding uninhibited by benzimidazoles 1 , 490 435602, AF217515, Hs 283532, uncharacteπzed bone marrow protein BM039, uπcharacteπzed bone marrow protein BM03, 489 0 452698, NM.001295 Hs 301921, chemokine (C-C motif) rxeptor 1, chemokine (C-C motif) receptor 1, 488
445333, BE537641, Hs 44278 hypothetical protein FLJ12538 similarto ras-related protein RAB17, hypothetical protein FLJ12538 similar to, 488 437162, AW005505 Hs 5464, thyroid hormone receptor coactivatmg protein, thyroid hormone rxeptor coxtivating pr, 487 441600, AA939347, Hs 127223 Homo sapienε cysteine knot protein (ZSIG51) mRNA, complete eds, Homo sapiens cysteine knot protein (ZSIG, 487 421350, AW301608, Hs 278188, ESTs, Moderately similar to I54374 gene NF2 protein [H sapienε], ESTs, Moderately similar to I54374 gene , 487 5 409093, BE243834, Hs 50441, CGI 04 protein, CGI-04 protein, 486
424304, NM_001395, Hε 144879, dual specificity phosphatase 9, dual spxificity phosphatase 9, 486 437696, Z83844, Hs 5790, hypothetical protein dJ37E16 5, hypothetical protein dJ37E165, 486
417381 , AF164142, Hs 82042, solute earner family 23 (nucleobase transporters), member 1 , solute earner family 23 (nuoleobase tra, 484 416445, AL043004, Hs 79337, KIAA0135 protein, KIAA0135 protein, 483 0 448939, BE267795, Hs 22595, hypothetical protein FLJ10637, hypothetical protein FLJ10637, 482
413566, AW604451, Hs 285814, sprouty (Drosophila) homolog 4, sprouty (Drosophila) homolog 4, 482 424081, NM.006413, Hs 139120, πbonuclease P (30kD), πbonuclease P (30kD), 481 425474, Z48054, Hε 158084, peroxiεome receptor 1, peroxiεome receptor 1, 481
412276, BE262621 , Hs 73798, macrophage migration inhibitory factor (glycosylation inhibiting factor), macrophage migration inhibitory factor ( 481 5 422689, AW856665, Hs 299797, gb RC3-CT0297-290100 013-d03 CT0297 Homo sapienε cDNA, mRNA εequence, gb RC3-CT0297-290100-013-d03 CT0297 Homo, 480
409101, NM 004297, Hε 50612, guanine nucleotide binding protein (G protein), alpha 14, guanine nuclxtide binding protein (G pr, 479 412760, AW379030, Hs 41324, ESTs, ESTs, 479
447250, AI878909, Hs 17883, protein phoεphataεe 1G (for eriy 2C), magneεium-dependent, gamma isoform, protein phosphatase 1G (formerty 2C), ma 479 429345, R11141, Hs 199695, hypothetical protein, hypothetical protein, 478 0 448950 AF288687, Hs 9275, CGI-152 protein, CGI-152 protein, 478
412926, AI879076, Hs 75061, mxrophage myπstoylated alanine πch C kinaεe εubεtrate, mxrophage myπstoylated alanine πch C , 478 412641, M16660, Hs 74335, heatshxk90kD protein 1, beta, heatεhxk 90kD protein 1, beta 476
420261 , AW206093, Hε 748, fibroblast growth fxtor rxeptor 1 (fms related tyrosine kinase 2, Pfeiffer syndrome), fibroblast growth fxtor receptor 1 (fms, 476 421905, AI660247, Hs 32699, ESTs, Weakly similar to UV-1 protein [H sapiens], ESTs, Weakly similar to UV-1 protein [H, 475 5 413880, AI660842, Hs 110915, interieukin 22 receptor, interleukin 22 rxeptor, 475
424905, NM.002497, Hs 153704, NIMA (never in mitosis gene a)-related kinase 2 (NEK2), NIMA (never in mitosis gene a) related k, 474 418355, L42563, Hs 1165, ATPase, H? transporting, nongaεtπc, alpha polypeptide, ATPase, H7 transporting, nongastπc, alp, 474 435905, AW997484, Hε 5003, KIAA0456 protein, KIAA0456 protein, 474
428024, Z29067, Hs 2236, NIMA (never in mitosis gene a)-related kinase 3, NIMA (never in mitosis gene a) related k, 474 O 421846, AA017707, Hs 1432, protein kinase C substrate 80K-H, protein kinase C substrate 80K-H, 472
419138, U48508, Hs 89631, ryanodine rxeptor 1 (skeletal), ryanodme rxeptor 1 (skeletal), 472 437296, AA350994, Hs 20281, KIAA1700, KIAA1700, 470
450142, AW207469, Hs 24485, chondroitin sulfate proteoglycan 6 (bamacan), chondroitin sulfate proteoglycaπ 6 (bama, 470 421733, AL119671 , Hs 1420, fibroblast growth fxtor rxeptor 3 (xhondroplasia, thanatophoπc dwarfism), fibroblast growth fxtor rxeptor 3 (ach, 469 5 449475, AI348027, Hs 129826, hypothetical protein PP1057, hypothetical protein PP1057, 469
420062, AW411096, Hs 94785, TGF(beta) induced transcnption fxtor 2, TGF(beta)-mduced transcnption fxtor 2, 469
429336, AB005038, Hs 199270, cytxhrome P450, subfamily XXVIIB (25-hydroxyvιtamιn D-1-alpha-hydroxylase), polypeptide 1, cytxhrome P450, subfamily XXVIIB (25-hy, 469 436856, AI469355, Hs 127310, ESTs, ESTs, 468
406937, U14622, , gb Human transketolaεe-like protein gene, partial cdε , gb Human tranεketolase-like protein gene, 467 0 411296, BE207307, Hs 10114, growth suppreεsor 1, growth εuppreεεor 1, 467
426726 AA488915, Hε 171955, trophmin assxiated protein (tastin), trophmm aεεxiated protein (taεtin), 467 409132, AJ224538, Hs 50732, protein kinase, AMP-xtivated, beta 2 non-catalytic subunit, protein kinase, AMP-xtivated, beta 2 no, 467 449230, BE613348, Hs 356392, melanoma cell adhesion molxule, melanoma cell adhesion molecule, 466 431681, AK000378, Hs 267566, hypothetical protein FLJ20371, hypothetical protein FLJ20371, 465 5 443623, AA345519, Hs 9641 , complement component 1 , q subcomponent, alpha polypeptide, complement ∞mponent 1 , q subcomponent, , 465
441595, AW206035, Hs 356457, ESTs, ESTs, 464 423419, R55336, Hs 23539, ESTs, ESTε, 464
415724, NM.003580, Hε 78687, neutral εphmgomyelinase (N-SMase) xtivation asεxiated fxtor, neutral εphingomyelmase (N-SMase) xtiv, 463 435045, BE297155, Hs 143698, ESTs, ESTs, 462 / 424441, X14850, Hs 147097, H2A histone family, member X, H2A histone family, member X, 462
414972, BE263782, Hs 77695, KIAA0008 gene product, KIAA0008 gene product, 462
436685 W28661 , Hs 5288, Homo sapiens mRNA cDNA DKFZp434M245 (from clone DKFZp434M245), Homo sapienε mRNA, cDNA DKFZp434M245 (fr, 462 449515, AI653378, Hε 302012, ESTε, ESTε, 461
425998, AU076629, Hs 165950, fibroblast growth fxtor rxeptor 4, fibroblast growth fxtor rxeptor 4, 461 / 5 420027, AF009746, Hs 94395, ATP-bindmg caεεette sub-family D (ALD) member 4, ATP-bmding cassette, sub-family D (ALD), 461
436469, AK001455, Hs 5198, Down syndrome critical region gene 2, Down syndrome cπtical region gene 2, 461 413441, AI929374, Hs 75367, Src like-adapter; Src like adapter; 460 456847, AI360456, Hs 86088, ESTs, ESTε, 458
421506, BE302796, Hs 105097, thymidine kinase 1, soluble, thymidiπe kmase 1, soluble, 457 O 426935, NMJ00088, Hs 172928, collagen, type I, alpha 1, collagen, type I, alpha 1, 457
428782, X12830, Hs 193400, interleukin 6 receptor, interleukin 6 rxeptor, 456 409430, R21945, Hs 346735, splicing factor, arginine/seπne πch 5, splicing fxtor, argmine/seπne πch 5, 456 412773, H15785, Hs 74573, similar to vaccinia virus Hindlll K4L ORF, similar to vaccinia virus Hindlll K4L OR 455 443068, AI188710, Hs 374480, ESTs, ESTs, 455
441607, NM_005010 Hs 7912, neuronal cell adhesion molecule, neuronal cell adhesion molecule 4 54 453227, AW135862, Hs 243991, ESTs, ESTs, 452
438459, T49300 Hs 35304, Homo sapιeπs cDNA FLJ13655 fis, clone PLACE1011503, Homo sapιens cDNA FLJ13655 fis clone PL 451 422565, BE259035 Hs 118400, singed (Drosophιla)-lιke (εea urchin faεcin homolog like), singed (Drosophila) like (sea urchin fas, 451
453613, F06838, Hs 374476, ESTs, ESTs, 450
413900, AW409747 Hs 75612, εtress-induced-phosphoprotein 1 (Hsp70/Hεp90-organιzιng protein), εtreεε induced phosphoprotem 1 (Hsp70/H, 450 412507, L36645, Hs 73964, EphA4, EphA4, 450
419034, NM.002110, Hs 89555, hemopoietic cell kinase, hemopoielic cell kinase, 449 413431, AW246428, Hs 75355, ubiquitm-conjugating enzyme E2N (homologouε to yeaεt UBC13), ubiquitin-conjugatmg enzyme E2N (homolo, 449
406547, , , Target Exon, Target Exon, 449
443216, W80487, Hs 324521 , hypothetical protein DC50, hypothetical protein DC50, 448 417497, AW402482 Hs 82212, CD53 antigen, CD53 antigen, 447 448595, AB014544, Hs 21572, KIAA0644 gene product, KIAA0644 gene product, 447 445350, AF052112 Hs 12540, lysophospholφase I, lysophospholipase 1, 446
446236, NM_006293 Hs 301, TYR03 protein tyrosine kinase, TYR03 protein tyrosine kinase, 446 429150, AF120103, Hs 197366, smoothened (Drosophila) homolog, sm∞thened (Drosophila) homolog, 446 420340, NM.000734, Hs 97087, CD3Z antigen, zeta polypeptide (TιT3 complex), CD3Z antigen, zeta polypeptide (TιT3 com, 446 413426, U88837, Hs 75354, GCN1 (general control of ammo-acid synthesis 1 , yeast) like 1, GCN1 (general control of amino-xid synt 444 421819, NM.013403, Hs 108665, zmedin, zmediπ, 444
409512, AW979187, Hs 293591, melanoma differentiation asεociated proteιn-5, melanoma differentiation associated prot, 444
428995, AW004975, Hs 194716, MAD (mothers against decapentaplegic, Drosophila) homolog interacting protein receptor activation anchor, MAD (mothers against dxapentaplegic
Dr, 443 434551 , BE387162, Hs 280858, ESTs, Highly similar to A35661 DNA excision repair cross-complementing protein ERCC3 [H sapiens] ESTs, Highly similar to A35661 DNA excis 443
418295, AW970043, Hs 238039, hypothetical protein FLJ11090, hypothetical protein FLJ11090, 442 409243, AB037761, Hs 51743, KIAA1340 protein, KIAA1340 protein, 442 437103, AW139408 Hs 152940, ESTs, ESTs, 442
413186, AU077141 , Hs 374548, solute carrier family 16 (monocarboxylic acid transporterε), member 1 , εolute earner family 16 (monxarboxylic, 442 456362, AW973003 Hs 179909, hypothetical protein FLJ22995, hypothetical protein FLJ22995, 440
424078, AB006625, Hs 139033, paternally expressed 3, paternally expressed 3, 439
448153, Y10805, Hs 20521, HMT1 (hnRNP methyltransferase, S cerevisiae) like 2, HMT1 (hnRNP methyltransferase, S cerevi, 437 410134, U68140, Hs 58927, nuclear VCP-like, nuclear VCP-like, 436
435523, T62849, Hs 11090, membrane-spanning 4-domaιπs, εubfamily A, member 7, membrane-spanning 4-domaιns, subfamily A 435 400440, X83957, Hs 83870, nebulin, nebuliπ, 435
437218, AL117497, Hs 58185, ESTs, Weakly similar to T42727 proliferation potential related protein - mouse [M musculus] ESTs, Weakly similar to T42727 prolifera, 434 430478, NM.014349, Hs 241535, apolipoprotein L, 3, apolipoprotein L, 3, 434 432744, AA988835, Hs 38664, ESTs, ESTs, 433
423173, AA442655, Hs 124942, protein phosphatase 2A 48 kDa regulatory subunit, protem phosphatase 2A 48 kDa regulatory, 433 415995, NM.004573, Hs 355888, phospholipase C, beta 2, phospholipaεe C beta 2, 433
408728, AL137379 Hε 47125, hypothetical protein FLJ13912, hypothetical protein FLJ13912, 430 431222, X56777, Hs 273790, zona pellucida glycoprotein 3A (sperm rxeptor), zona pellucida glycoprotein 3A (sperm re, 430 427792, M63928, Hs 180841 , tumor nxrosiε factor rxeptor εuperfamily, member 7, tumor nxrosis fxtor rxeptor superfami, 429 426227, U67058, Hs 154299, Human proteinase xtivated rxeptor-2 mRNA, 3 UTR, Human proteinase xtivated rxeptor 2 R 429 427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lllb, receptor for (CD16), Fc fragment of IgG, low affinity lllb, r, 429
434826, AF155661, Hs 22265, pyruvate dehydrogenase phosphatase, pyruvate dehydrogenase phosphatase, 429
412314, AA825247, Hs 356084, downstream of G protein-coupled receptor 27 (GPR27) (SREB1), downstream of G protein-coupled rxepto, 428 447827, U73727, Hs 19718, protein tyrosine phosphatase, rxeptor type, U, protein tyrosine phosphatase, rxeptor t, 428 426108, AA622037, Hs 166468, programmed cell death 5, programmed cell death 5, 428 428820, AA436187, Hs 172631 , integπn, alpha M (complement component rxeptor 3, alpha, also known as CD11 b (p170), macrophage antigen alpha polypeptide), integπn, alpha M
(complement component , 427 437908, AI082424, Hs 351043, ESTs, ESTs, 427
444664, N26362, Hs 11615, map kinase phosphatase like protein MK-STYX map kinase phosphatase-like protein MK-S, 427 429002, AW248439, Hs 2340, junction plakoglobm, junction plakoglobm, 426 439334, AH48976, Hs 112062, ESTs, ESTs, 426
425308, M97639, Hs 155585, rxeptor tyrosine kinaεe-like oφhan rxeptor 2, rxeptor tyrosine kmase-like orphan rx, 425 413869, NM.000878, Hs 75596, interieukin 2 receptor, beta, interieukin 2 rxeptor, beta, 425 453648, W21493, Hε 380100, hypothetical protein FLJ14005, hypothetical protein FLJ14005, 424
447200, BE543146, Hs 281434, Homo sapiens cDNA FLJ14028 fis, clone HEMBA1003838, Homo sapienε cDNA FU14028 fis, clone HE, 424 447528, A1612027, Hs 76277, Homo sapiens, clone MGC 9381, mRNA, complete eds, Homo sapiens, clone MGC 9381, mRNA, comp, 423
452721, AJ269529, Hs 301871, solute camerfamily 37 (glycerol-3-phosphate transporter), member 1, solute camerfamily 37 (glycerol-3-pho, 422 449810, AB008681, Hs 23994, xtivm A rxeptor, type UB. xtivm A rxeptor, type IIB, 422 447198, D61523, Hs 283435, ESTs, ESTε, 422
416714, AF283770, Hε 79630, CD79A antigen (immunoglobulin aεεxiated alpha), CD79A antigen (immuπoglobulin-assxiated, 422 425356, BE244879, Hε 155939, moεitol polyphoεphate-5-phosphatase, 145kD, mositol polyphosphate-5-phosphatase, 14, 422
422605, H16646, Hs 118666, hypothetical protein PP591, hypothetical protein PP591, 421
444535, AF011466, Hs 122575, EDG-4 (endothelial differentiation, lysophoεphatidic xid G-protem-coupled rxeptor, 4), EDG 4(endothelιal differentiation, lys, 421 417088, M54915, Hε 81170, pιm-1 oncogene, pιm-1 oncogene, 420 421707, NM.014921, Hs 107054, lxtomedιn-2, lxtomedιn-2, 420 408717, AF045458, Hs 47061 , uπc-51 (C elegans)-lιke kinase 1, unc-51 (C elegans) like kinase 1, 420
438485, W57578, Hε 378718, RAB7, member RAS oncogene family, RAB7, member RAS oncogene family, 419 419452, U33635, Hs 90572, PTK7 protein tyrosine kinase 7, PTK7 protein tyrosine kinase 7, 4 18 418755, Y14443, Hs 88219, zinc finger protein 200, zinc finger protein 200, 4 18 417212, AW952823, Hs 351547, NS1-bιndιng protein, NS1-bιndιng protein, 4 17 413686, AI469213, Hs 71404, ESTs, ESTs, 4 17
419344, U94905, Hs 277445, dixylglycerol kinase, zeta (104kD), diacylglycerol kinase, zeta (104kD), 4 16 418870, AF147204, Hε 89414, chemokine (C-X-C motif), receptor 4 (fuεin), chemokine (C-X-C motif), rxeptor 4 (fuε, 4 16 408482, NM.000676, Hε 45743, adeπosme A2b receptor, adenosme A2b rxeptor, 4 16 422391, D63479, Hs 115907, dixylglycerol kinase, delta (130kD), diacylglycerol kinase, delta (130kD), 4 15 409421, AA199883, Hs 67624, ESTs, ESTs, 4 15
415938, BE383507, Hs 78921, A kinase (PRKA) anchor protein 1, A kmase (PRKA) anchor protem 1, 4 14
415198, AW009480, Hs 943, natural killer cell transcript 4, natural killer cell transcπpt 4, 4 14
424685 W21223, Hs 151734, nuclear transport fxtor 2 (plxental protein 15), nuclear transport fxtor 2 (plxental pr; 4 13 428479, Y00272, Hs 334562, cell division cycle 2, G1 to S and G2 to M, cell division cycle 2, Gl to S and G2 to, 4 13
423728, AW891294, Hs 132136, solute earner family 4, εodium bicarbonate cotranεporter, member 8, solute carrier family 4, sodium bicarbon, 4 13 433435, BE545277, Hs 340959, Ts translation elongation factor, mitochondnal, Ts translation elongation factor, mitxh, 4 13 420253, AI656055, Hs 96200, neighbor of A-kinase anchoπng protein 95, neighbor of A kinase anchoπng protein 9, 4 12 412584 X54870, Hs 74085, DNA segment on chromosome 12 (unique) 2489 expressed sequence, DNA segment on chromosome 12 (unique) 24 4 12
400205, , Hs 81848, NM.006265* Homo sapienε RAD21 (S pombe) homolog (RAD21), mRNA (APO-1/CD95 (Fas)-assxιated phoεphatase) (PTPN13), mRNA ,
NM.006265* Homo εapienε RAD21 (S pombe), 4 12 425322, U63630, Hs 155637, protein kmase, DNA-activated, catalytic polypeptide, protein kinase, DNA-activated, catalytic, 4 11 « 419607, R52557, Hs 91579, Homo sapiens clone 23783 mRNA sequence, Homo sapienε clone 23783 mRNA sequence, 4 10 459035, AW291109, Hs 332563, ESTs, Weakly similar to T31611 hypothetical protein Y50E8A g - Caenorhabdifis elegans [C elegans], ESTε, Weakly similar to T31611 hypotheti
410 432512, NM.003284, Hs 3017, transition protein 1 (during histone to protamine replacement), transition protein 1 (during histone to , 4 10 452875, BE275760, Hs 30928, DNA segment on chromosome 19 (unique) 1177 expressed sequence, DNA segment on chromosome 19 (unique) 11, 409 423804, AW403448, Hs 1706, interferon stimulated transcnption factor 3, gamma (48kD), interferon stimulated transcription fxt, 409 413745, AW247252, Hs 75514, nucleoside phosphorylase, nucleoside phosphorylase, 409
442091, AW770493, Hs 182874, guanine nucleotide binding protein (G protein) alpha 12, guanine nucl∞tide binding protein (G pr, 409 425003, AF119046, Hs 154149, apuπnic/apyπmidmic eπdonuclease(APEX nuclease)-lιke 2 protein, apuπmc/apyπmidinic endoπucleasejAPEX , 408 421859, AA356620, Hs 108947, KIAA0050 gene product, KIAA0050 gene product, 408
432841 , M93425, Hs 62, protein tyrosine phosphataεe, non-rxeptor type 12, protein tyrosine phosphatase, non-rxept, 408 452069, A8028949, Hs 183994, KIAA1026 protein, KIAA1026 protein, 408
425069, AA687465, Hs 298184, potassium voltage-gated channel, shaker-related subfamily, beta member 2, potassium voltage-gated channel, shaker-, 4 07 418526, BE019020, Hs 85838, solute carrier family 16 (monxarboxylic xid transporterε), member 3, εolute carrier family 16 (monxarboxylic, 407 424517, AI539443, Hs 137447, Homo sapienε cDNA FLJ12169fis, clone MAMMA1000643, Homo sapienε cDNA FLJ12169 fiε, clone MA, 407 434224, AA380731 , Hε 84, interleukin 2 rxeptor, gamma (εevere combined immunodeficiency), interieukin 2 rxeptor, gamma (severe co, 406 446791, AI632278, Hs 195922, ESTs, ESTs, 406
432065, AA401039, Hε 2903, protein phosphatase 4 (formerly X), catalytic subunit, protein phosphataεe 4 (formerly X), cata, 406 431194, D43704, Hs 250712, calcium channel, voltage-dependent, beta 3 subunit, calcium channel, voltage-dependent, beta, 406 418751, BE389014, Hs 372548, phosphoιnosιtιde-3-kιnaεe, regulatory subunit, polypeptide 3 (p55, gamma), phosphoinosιtιde-3-kiπase, regulatory su, 406 425923, NM_005026, Hs 162808, phosphoino8itιde-3-kιπaεe, catalytic, delta polypeptide, phoεphoιπosιtιde-3-kιnase, catalytic, de, 405 408692, AL040127, Hs 34074, dipeptidylpeptidase VI, dipeptidylpeptidase VI, 404
446272, BE268912, Hε 14601, hematopoietic cell-εpxific Lyπ εubstrate 1, hematopoietic cell-spxific Lyπ substrat, 404 439176, AI446444, Hs 190394, ESTs, Weakly similarto B28096 lιne-1 protein ORF2 [H sapiens], ESTs, Weakly similarto B28096 lιne-1 pr, 404 417880, BE241595, Hs 82848, selectin L (lymphxyte adhesion molecule 1) selxtin L (lymphocyte adhesion molxule, 404 410068, AI633888, Hs 58435, FYN-binding protein (FYB-120/130), FYN-bindiπg protein (FYB-120/130), 403 410639 BE269047, Hs 65234, hypothetical protein FLJ20596, hypothetical protein FLJ20596, 403
427716, L38951, Hs 180446, karyophenn (importin) beta 1, karyophenn (importin) beta 1, 403 451050, AW937420, Hs 351869, ESTs, ESTε, 402 449667, AB023227, Hε 23860, KIAA1010 protein, KIAA1010 protein, 402 448499, BE613280, Hs 77550, p53-regulated DDA3, p53-regulated DDA3, 401 437527, AI241019, Hs 145644, ESTs, ESTs, 4 01
425118, AU076611 , Hs 154672, methylene tetrahydrofolate dehydrogenase (NAD dependent), methenyltetrafiydrofolate cyclohydrolase, methylene tetrahydrofolate dehydrogenase
400 451931, AK000208, Hs 27267, Homo sapienε cDNA FLJ20201 fis, clone COLF1210, Homo sapiens cDNA FLJ20201 fis, clone CO, 400 412939, AW411491 , Hs 75069, eukaryotic translation elongation fxtor 1 gamma, eukaryotic translation elongation factor, 400 409581, U66243, Hs 55039, mitogen-xtivated protein kinase 12, mitogen-xtivated protein kinase 12, 399
433577, AW007080, Hs 284192, ESTs, ESTs, 399
439963, AW247529, Hs 6793, platelet-activating fxtor xetylhydrolase, lεoform lb, gamma εubuπit (29kD), platelet-activating fxtor xetylhydrola, 399 418629, BE247550, Hs 86859, growth fxtor receptor-bound protein 7, growth fxtor receptor-bound protein 7, 399 448633, AA311426, Hs 21635, tubulin, gamma 1, tubulin, gamma 1, 398 402398, , , C19000263 gι|3108023|gb]AAC15755 1| (AC004659) BC62940.2 [Homo sapιens]||66335, C19000263 gι|3108023|gb|AAC15755 1| (AC0, 397
408414, AH 14688, Hs 193400, ESTs, Weakly similarto 2109260A B cell growth fxtor [H sapienε], ESTε, Weakly similarto 2109260A B cell , 397 415012, NM.004383, Hs 77793, c-src tyroεine kinaεe, c-εrc tyroεine kinase, 397
416084, L16991, Hs 79006, deoxythymidylate kinase (thymidylate kinase), deoxythymidylate kinase (thymidylate km, 395
422051 , AW327546, Hs 111024, solute earner family 25 (mitxhondπal earner, citrate transporter), member 1 , solute earner family 25 (mitochondnal , 395 447887, AA114050, Hs 211610, caspase 8, apoptosis-related cysteine protease, caspaεe 8, apoptosis-related cysteine pπ 395
430770, AA765694, Hs 123296, ESTs, ESTs, 394 442994, AI026718, Hs 16954, ESTs, ESTs, 394
420333, AJ001383, Hs 97084, lymphxyte antigen 94 (mouse) homolog (xtivatmg NK-rxepton NK-p46), lymphxyte antigen 94 (mouse) homolog (a, 394 438456, AA913381, Hs 279763, ESTs, ESTs, 394 422599, BE387202, Hs 118638, non-metastatic cells 1 , protein (NM23A) expressed in, noπ-metastatic cells 1 , protein (NM23A) , 393
420162, BE378432, Hs 95577, cyclm-dependent kinase 4, cyclm-dependent kinase 4, 393
424829, NM.002507, Hs 1827, nerve growth factor rxeptor (TNFR superfamily, member 16), nerve growth fxtor rxeptor (TNFR super, 393 447574, AF162666, Hs 18895, tousled-like kinase 1, tousled-like kinase 1, 393
425797, AF002986, Hs 159545, platelet xtivatmg rxeptor homolog, platelet xtivatmg rxeptor homolog, 393 421910, NM_014586, Hs 109437, hormonally upregulated neu tumor-assxiated kinase, hormonally upregulated neu tumor-ass∞ia, 392
413781, J05272, Hs 850, IMP (inosine monophosphate) dehydrogenase 1, IMP (inosine monophosphate) dehydrogenas, 392 434334, AA912476, Hs 116750, Homo sapienε cDNA FLJ13221 fiε, clone NT2RP4002075, Homo sapiens cDNA FLJ13221 fis, clone NT, 392 400262, , Hs 75309, Eos Control, Eos Control, 390
424977, AA349289, Hs 100057, Homo sapienε cDNA FLJ22902 fis, clone KAT05581, Homo sapiens cDNA FU22902 fis, clone K, 390 409799, D11928, Hs 76845, phosphoseπne phosphataεe-like, phoεphoεeπne phoεphataεe-like, 390
435206, AI432364, Hs 160594, ESTs, ESTs, 3 90
439863, BE547830, Hs 375208, paired immunoglobulin-like receptor beta paired immunoglobulin-like rxeptor beta, 390 413627, BE182082, Hs 246973, intron of Bicaudal D homolog 1, intron of Bicaudal D homolog 1, 390 426265, AA421069, Hs 97896, ESTε, ESTε, 389 451063, AW163702, Hs 25911, HLA-B assxiated tranεcπpt-2, HLA-B assxiated transcπpt-2, 389
407013, U35637, Hs 83870, gb Human nebulm mRNA, partial eds, gb Human nebulin mRNA, partial eds, 389 437239, AW503395, Hs 5541, ATPase, Ca transporting, ubiquitous, ATPase, Ca transporting, ubiquitous, 388 400261, , Hs 1802, Eos Control, Eos Control, 3 88
450447, AF212223, Hs 25010, hypothetical protein P15-2, hypothetical protein P15-2, 388 422293, X94453, Hε 114366, pyrτolιne-5-carboxylate synthetaεe (glutamate gamma-semialdehyde synthetase), pyrroIιne-5-carboxylate synthetase (glut, 387
414251, AL042306, Hs 97689, VASA protein, VASA protein, 387
417767, BE242241, Hs 82542, acyloxyaeyl hydrolase (neutrophil), acyloxyxyl hydrolase (neutrophil), 3 87 414443, AU077268, Hs 76144, platelet-deπved growth fxtor receptor, beta polypeptide, platelet-deπved growth factor rxeptor,, 387 444099, D87432, Hs 10315, solute earner family 7 (cationic ammo xid transporter, y syεtem), member 6 εolute carrier family 7 (cationic ammo , 386 419596, BE379320, Hs 91448, MKP-1 like protein tyrosine phosphatase, MKP-1 like protein tyrosine phosphataεe, 386 427022, AW245839 Hε 173255, εmall nuclear πbonucleoprotein polypeptide A, εmall nuclear ribonucleoprotem polypept, 386 443661, AA336609, Hs 10862, Homo sapiens cDNA FLJ23313 fis, clone HEP11919, Homo sapiens cDNA FLJ23313 fiε, clone H, 386 408056, AA312329, Hε 42331 , ephπn A4, ephπn A4 386
410552, X66945, Hε 748, fibroblast growth factor receptor 1 (fms related tyrosine kinase 2, Pfeiffer εyndrome), fibroblast growth fxtor receptor 1 (fms, 385 450778, U81375, Hs 25450, solute earner family 29 (nucleoside transporters), member 1 , solute carrier family 29 (nucleoside tra, 385 418978, T85295, Hs 268606, ESTs, ESTs, 384
429903, AL134197, Hε 93597, cyclin dependent kinase 5, regulatory εubunit 1 (p35), cyclm-dependent kmase 5, regulatory εu, 384 442980 AA857025, Hε 8878, kiπeεm-like 1 , kiπeεm like 1 , 384
447232, AW499834, Hs 327, interleukin 10 receptor, alpha, interleukin 10 receptor, alpha, 384
434689, AF154115, Hs 4076 CTD (carboxy-termmal domma, RNA polymeraεe II, polypeptide A) phoεphatase, subunit 1, CTD (carboxy terminal domina, RNA polyme, 383 432539, AL138169, Hs 278378, karyophenn beta 2b, transportin karyophenn beta 2b, transportin, 383 415684, D59356, Hs 374480, sorbitol dehydrogenase sorbitol dehydrogenase, 383 5 451598, N29102, Hs 79658, ESTs, ESTs, 382
449433, AI672096, Hs 9012, ESTs, Weakly similar to S26650 DNA binding protein 5 [H εapienε], ESTε, Weakly similar to S26650 DNA bmdi, 3 82 426359 AA376409, Hs 10862, Homo εapieπs cDNA FLJ23313 fiε, clone HEP11919, Homo εapiens cDNA FLJ23313 fis, clone H, 381 435160, AB002374, Hs 4791, KIAA0376 protein, KIAA0376 protein, 3 80
443402, U77846, Hs 9295, elastm (supravalvular xrtic εtenosis, Williams Beuren syndrome), elastin (εupravalvular aortic stenosis, , 380 0 422753, AI928995, Hs 1575 small nuclear ribonucleoprotem D3 polypeptide (18kD), small nuclear ribonucleoprotem D3 polyp, 379
421508, NM.004833 Hs 105115, absent in melanoma 2, absent in melanoma 2, 379 414806, D14694, Hs 77329 phosphatidylseπne synthase 1, phosphatidylseπne εyπthaεe 1, 379
428023, AL038843, Hε 374530, Homo sapiens cDNA FLJ23602 fis, clone LNG15735 Homo εapieπs cDNA FLJ23602 fis, clone L, 379 421654, AW163267, Hs 106469, suppressor of varl (S cerevisiae) 3-lιke 1 , εuppressor of varl (S cereviεiae) 3-lιke, 379 5 439668, AI091277, Hε 302634, fπzzled (Drasophila) homolog 8, fπzzled (Drosophila) homolog 8, 379
411125, AA151647, Hs 68877, cytxhrome b-245 alpha polypeptide, cytxhrome b-245, alpha polypeptide, 378 429170, NM.001394, Hs 2359, dual spxificity phosphatase 4, dual spxificity phosphatase 4, 378 425354, U62027, Hε 155935, complement component 3a receptor 1 , complement component 3a rxeptor 1 , 378 423909, AJ223183, Hs 135194, immunoglobulin superfamily, member 6, immunoglobulin superfamily, member 6, 378 O 429687, AI675749, Hs 211608, πucleopoπn 153kD nucleopoπn 153kD, 377
414177, AI351355, Hs 356303, uncharxteπzed hypothalamus protein HARP11, uπcharacteπzed hypothalamus protein HAR, 377 414135, NM.004419, Hs 2128, dual spxificity phosphataεe 5, dual εpxificity phoεphatase 5, 377 445817, NMJ03642 Hs 13340, histone acetyltransferase 1, histone xetyltransferase 1, 377
410422, AL042014, Hs 63348, Homo sapiens, clone MGC 15203, mRNA, complete eds, Homo sapiens, clone MGC 15203, mRNA, com 376 5 412146, M92444, Hs 73722, APEX nuclease (multifunctional DNA repair enzyme), APEX nuclease (multifunctional DNA repai, 376
413011, AW068115, Hs 821, biglycan, bigiycan, 376 428157, AI738719, Hs 198427, hexokmase 2, hexokmase 2, 376
400288, X06256, Hs 149609, integnn, alpha 5 (fibronectin rxeptor, alpha polypeptide), integπn, alpha 5 (fibroπxtin rxeptor,, 375 427378, BE515037, Hs 177556, melanoma antigen, family D, 1, melanoma antigen, family D, 1, 375 0 405484, , , C3002124* gι|12737280|ref]XP_0066822| keratin 18 [Homo sapιeπs]||6633, C3002124* g ι| 12737280 |ref|XP_0066822| k, 375
450998, BE387614 Hs 25797, splicing fxtor 3b, subunit 4, 49kD, splicing factor 3b, subunit 4, 49kD, 375 432460, H12912, Hs 274691, adenylate kmase 3, adenylate kmase 3, 375
428816, AA004986, Hε 193852, ATP-binding cassette, sub-family C (CFTR/MRP), member 2, ATP-bindmg cassette, sub-family C (CFTR, 374
431884, AA521246, Hε 210792, ESTε, Weakly similar to ALU8JHUMAN ALU SUBFAMILY SX SEQUENCE CONTAMINATION WARNING ENTRY [H sapiens], ESTs, Weakly similar 5 to ALU8JHUMAN ALU S, 374
453329, T97205, Hs 193400, ESTε, Weakly similar to 2109260A B cell growth fxtor [H sapiens], ESTs, Weakly similar to 2109260A B cell , 374 426440, BE382756, Hε 169902, εolute earner family 2 (facilitated glucoεe tranεporter), member 1 , solute earner family 2 (facilitated glu, 374 438330, AW450572, Hs 257316, ESTs, ESTs, 374
419911 , L15301 , Hs 1276, BN51 (BHK21) temperature sensitivity complementing, BN51 (BHK21) temperature sensitivity com, 374 0 452695, AW780199, Hs 30327, mitogen-xtivated protein kinase xtivated protein kmase 5, mitogen activated protein kmase-xtivat, 373
442233, AW967149, Hs 28439, ESTs, Weakly similarto I38022 hypothetical protein [H sapiens] ESTs, Weakly similar to I38022 hypotheti, 373 451295, AI557212, Hs 17132, ESTs, Moderately similar to I54374 gene NF2 protein [H sapiens], ESTs, Moderately similar to I54374 gene , 373 410772, BE275297, Hs 194685, Homo sapienε clone 24675 mRNA εequence, Homo εapiens clone 24675 mRNA sequence, 373 426251, M24283, Hs 168383, intercellular adhesion molecule 1 (CD54), human rhinoviruε rxeptor, intercellular adhesion molxule 1 (CD54), 372 5 449843, R85337, Hs 24030, solute earner family 31 (copper transporters), member 2, solute earner family 31 (copper transpo, 371
423523, AW299828, Hε 193580, ESTε, ESTs, 371
413407, AI356293, Hs 75339, mositol polyphoεphate phoεphataεe-like 1, oεitol polyphoεphate phoεphataεe like , 371 448336, R53848, Hs 44976, ESTs, ESTs, 370
422083, NM_001141, Hs 111256, arachidonate 15-lιpoxygenase, sxond type, arxhidonate 15-lιpoxygenaεe, εxond typ, 370 0 416087, AF045184, Hs 79008, SKI-INTERACTING PROTEIN, SKI-INTERACTING PROTEIN, 370
442200, AW590572, Hs 235768, ESTs, ESTε, 370 414280, BE410769, Hε 75873, zyxin, zyxm, 369
409354, N68188, Hε 159472, Homo εapieπε cDNA FLJ22224 fis, clone HRC01703, Homo sapiens cDNA FLJ22224 fis, clone H, 369 415276, U88666, Hs 78353, SFRS protein kinaεe 2, SFRS protein kinaεe 2, 369 5 439659, AW970780, Hε 59483, leucine-πch repeat-containing G protein-coupled rxeptor 6 (LGR6) mRNA, leuc e-πch repeat-containing G protein, 3 69
446522, NMJ03876, Hs 15196, putative rxeptor protein, putative receptor protein, 3 69 422785, AI824114, Hs 289088, heat shxk 90kD protein 1, alpha, heat εhxk 90kD protein 1, alpha, 368
401083, , , NM_016582* Homo sapiens peptide transporter 3 (LOC51296), mRNA VERSION NM_016579 1 Gl, NM_016582* Homo sapieπε peptide tranεpoπ 368 413048, M93221, Hε 75182, mannoεe rxeptor, C type 1 , mannose receptor, C type 1 , 368 0 452690, AI536070, Hs 15085, ESTs, ESTs, 3 68
428981, BE313077, Hs 93135, ESTs, Weakly similar to ALU2_HUMAN ALU SUBFAMILY SB SEQUENCE CONTAMINATION WARNING ENTRY [H sapienε], ESTε, Weakly similar to ALU2_HUMA ALU S, 3 68 415010, NM.004203 Hs 77783, membrane-aεsociated tyrosine- and thrxnme-spxific cdc2-mhιbιtory kmase, membraπe-asεxiated tyroεine- and threon, 368 428579, NM.005756, Hs 184942, G protein-coupled rxeptor 64, G protein-coupled receptor 64, 368 5 446430, AA346837, Hs 15075, hypothetical protein DKFZp434E2216, hypothetical protein DKFZp434E2216, 366
442013, AA506476, Hs 375009, Human DNA sequence from clone RP11-353C18 on chromosome 20 Contains ESTs, STSs, GSSs and CpG islands Contains the NIFS gene for cysteine desulfurase, two genes for novel proteins and the gene for the, Human DNA sequence from clone RP11-353C1 , 366 416602, NMJ06159, Hs 367895, Protein kmase C-bindmg protein NELL2, Protein kinase C-bmding protein NELL2, 365 . 441226, BE563042, Hs 118820, Homo sapiens, Similarto RIKEN cDNA 0610012G03 gene, clone MGC 14132, mRNA, complete eds, Homo sapiens, Similarto RIKEN cDNA 0610, O 365
413076, U10564, Hs 75188, weel (S pombe) homolog weel (S pombe) homolog, 365
429303, AW137635, Hs 44238, ESTs, Weakly similar to S65657 alpha 1C-adrenergιc receptor splice form 2 [H sapienε], ESTs Weakly similar to S65657 alpha 1C-, 365
452060, W26980, Hs 349089, ATP-bmding casεette sub-family F (GCN20), member 2, ATP binding cassette, sub-family F (GCN2, 365 451558, NM.001089, Hs 26630, ATP binding cassette, sub-family A (ABC1), member 3, ATP-bindmg cassette, sub family A (ABC1, 365 414774, X02419, Hε 77274, plaεminogen activator, urokmase, plasminogen xtivator, urokmase 365 417426, NM.002291, Hs 82124, laminin beta 1, laminin, beta 1, 365
450296, AL041949, Hs 24756, hepatocyte growth factor-regulated tyrosine kinase substrate, hepatocyte growth factor-regulated tyros, 364 437669, AI358105 Hs 123164, ESTs, Weakly similar to match to ESTε AA667999 [H sapiens], ESTε, Weakly similar to match to ESTs AA 364
414029, BE297731, Hs 75709, manπose 6-phosphate receptor (cation dependent), mannose-6 phosphate receptor (cation dep, 364 444388, AB033058, Hs 11101, KIAA1232 protein, KIAA1232 protein, 364
425910, AA830797, Hs 184760, CCAAT box-binding transcription fxtor, CCAAT-box binding transcnption factor, 363 451484, AV648896 Hs 283771 , hypothetical protein, hypothetical protein, 363 444613, H29627, Hs 79092, hypothetical protein FLJ14427, hypothetical protein FLJ14427, 363
447495, AW401864 Hs 18720, programmed cell death 8 (apoptosis inducing factor), programmed cell death 8 (apoptosis indue, 362 408101, AW968504 Hs 278346, CDC2-related protein kmase 7, CDC2 related protein kinase 7, 362 424732, D80001, Hs 152629, KIAA0179 protein, KIAA0179 protein, 362 411165, NM 000169, Hs 69089, galactosidase, alpha, galactosidaεe, alpha, 362 422112, BE540240, Hs 111783, Lsm1 protein, Lsm1 protein, 362
453020, AL162039, Hs 31422, Homo sapienε mRNA, cDNA DKFZp434M229 (from clone DKFZp434M229), Homo εapiens mRNA, cDNA DKFZp434M229 (fr, 361 438795, AA825792, Hs 377119, gb od84b11 s1 NCI_CGAP_Ov2 Homo sapiens cDNA clone, mRNA sequence, gb od84b11 s1 NCI_CGAP_Ov2 Homo εapiens , 361 445515, BE388665, Hs 179999, Homo sapiens, clone IMAGE 3457003, mRNA, Homo sapienε, clone IMAGE 3457003, mRNA, 361 407797, AK000524, Hε 39850, hypothetical protein FLJ20517, hypothetical protein FLJ20517, 360 423217, NM.000094, Hs 1640, collagen, type VII, alpha 1 (epidermolysiε bulloεa, dystrophic, dominant and recesεive), collagen, type VII, alpha 1 (epidermolys, 360
444985, AI677737, Hs 380100 hypothetical protein FLJ14005 hypothetical protem FLJ14005, 360 433764, AW753676, Hs 39982, zinc finger protein RINZF (NM.023929), zinc finger protein RINZF (NM.023929), 3 59 427857, AL133017, Hs 288679, hypothetical protein FLJ22865, hypothetical protein FLJ22865, 359
415020, BE249915, Hs 293533, Human DNA sequence from clone RP11-127L20 on chromosome 10 Contains ESTs, STSs, GSSs and CpG islands Contains the gene for a novel glutathione S-transferase and five novel genes, Human DNA sequence from clone RP11-127L2, 359
415149, X12451, Hs 78056 cathepsin L, cathepsin L, 357
458715, AK000973, Hs 1706, hypothetical protein FLJ10111, hypothetical protein FLJ10111, 357
423576, NM.000383, Hs 129829, autoimmune regulator (automimmune polyendxπnopathy candidiaεis xtodermal dystrophy), autoimmune regulator (automimmune polyen, 357 440270, NM.015986, Hs 7120, cytokine rxeptor-like molecule 9, cytokine receptor-like molxule 9, 357 434883, AW381538, Hs 19807, hypothetical protein MGC12959, hypothetical protein MGC12959, 357
404976, , , NM.014323* Homo sapienε zinc finger protein 278 (ZNF278), transcπpt vaπant 1, mRNA , NM.014323* Homo sapienε zinc finger prot 357 449656, AA002008, Hs 188633, ESTs, ESTs, 356 413795, AL040178, Hs 142003, ESTε, ESTε, 356
406859, AI581134, Hs 181357, laminin rxeptor 1 (67kD, πbosomal protein SA), lammm rxeptor 1 (67kD, πbosomal prot, 356 411030, BE387193, Hs 67896, 7-60 protein, 7-60 protein, 356
447079, AA280057, Hs 105280, ESTε, Weakly similar to dJ963K232 [H sapiens], ESTs, Weakly similar to dJ963K232 [H sa, 3 56
424263, M77640, Hs 1757, L1 cell adhesion molxule (hydrxephalus, stenoεiε of aqueduct of Sylvius 1, MASA (mental retardation, aphasia, shuffling gait and adducted thumbs) εyndrome, εpaεtic paraplegia 1), L1 cell adheεion molxule (hydrocephaluε, 355 413472, BE242870, Hs 75379, solute earner family 1 (glial high affinity glutamate transporter), member 3, solute earner family 1 (glial high affi, 355 443466, BE243123, Hs 321045, IKK-related kinase epsilon, inducible IkappaB kinase, IKK-relaied kinase epsilon, inducible Ik, 355
426746, J03626, Hs 2057, undine monophosphate synthetase (orotate phosphoπbosyl transferase and orotιdιne-5'-dxarboxylase), undine monophosphate synthetase (orotat, 3 55 450931, N25156, Hs 25648, tumor necrosis factor receptor superfamily, member 5, tumor necrosis factor rxeptor superfami, 355 425836, AW955696, Hs 90960, ESTε, ESTε, 354 441054, AA913591, Hε 126480, ESTs, ESTs, 354 440592, AL137268, Hs 7285, KIAA0759 protein, KIAA0759 protein, 354
458946, AA009716, Hs 42311, ESTs, ESTs, 353
449027, AJ271216, Hs 22880, dipeptidylpeptidase III, dipeptidylpeptidase III, 353 421662, NM.014141, Hs 106552, cell rxogmtion molxule Caspr2, cell recognition molxule Caspr2, 353 422732, AA577455, Hs 24937, traπsformer-2 alpha (htra-2 alpha), transformer-2 alpha (htra-2 alpha), 353 424870, T15545, Hε 244624, ESTε, ESTs, 352
442794, AI744130, Hs 356753, hypothetical protein MGC2975, hypothetical protein MGC2975, 352 417640, D30857, Hs 82353, protein C rxeptor, endothelial (EPCR), protein C rxeptor, endothelial (EPCR), 351
419971, AA400027, Hs 296234, ESTs, Weakly similar to T31613 hypothetical protein Y50E8A i - Caeπorhabditis elegans [C elegans], ESTs, Weakly similar to T31613 hypotheti, 351 410257, BE244044, Hs 61469, hypothetical protein, hypothetical protein, 351 424837, BE276113, Hs 333034, N-acetyitraπsferaεe, homolog of S cerevisiae ARD1 , N acetyltransferase, homolog of S cerev, 351
421921, H83363, Hε 355993, tranεlxase of inner mitochondnal membrane 10 (yeast) homolog, translxase of inner mitxhoπdnal membr, 350 454128, AL031259, Hs 367900, programmed cell death 2, programmed cell death 2, 350
434049, AA501430, Hs 5771 , amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2, amyotrophic lateral scleroεiε 2 (juvenil, 350 453641, AA444140, Hε 90960, ESTε, ESTε, 350 429592, AB029041, Hε 209646, KIAA1118 protein, KIAA1118 protein, 349
430647, AC003682, Hs 127988, ESTs, Weakly similar to Z211.HUMAN ZINC FINGER PROTEIN 211 [H sapienε], ESTε, Weakly similar to Z211.HUMAN ZINC , 347 410855, X97795, Hs 66718, RAD54 (S cerevisiae) like, RAD54 (S cerevιsιx)-lιke, 344 413372, H55532, Hε 349695, tubulin, alpha 2, tubulin, alpha 2, 3 07 437224, AL117628, Hε 97808, ESTε, ESTs, 277 430439, AL133561, , DKFZP434B061 protein, DKFZP434B061 protein, 276
435897, AF269223, Hs 128322, t-complex 11 (a munne top homolog), t-complex 11 (a munne top homolog), 253
417592, AA204664, Hs 182437, ESTs, Weakly similar to I54383 chromosome segregation protein smc1 [H sapiens], ESTs, Weakly similar to I54383 chromosom, 246 412026, AA383618, Hs 73073, testis-specific ankyππ motif containing protein, testis-εp cific ankyπn motif containing, 235 422789, AK001113, Hs 120842, hypothetical protein FLJ10251, hypothetical protein FLJ10251, 233 426627, AF012359, Hs 195685, ESTs, ESTs, 2 12
438983, AF085884, Hs 20029, proxrosiπ binding protein sp32 prxursor; proxrosin binding protein εp32 prxurεo, 207 425709, AA383076, Hs 159274, outer dense fibre of sperm tails 1 , outer dense fibre of sperm tails 1 , 1 99 433724, AI827749, Hs 144924, senne/thr∞πine protein kinase SSTK, seπne/threonme protein kinase SSTK, 1 68 420710, NM.007009, Hs 99875, zona pellucida binding protein, zona pellucida binding protein, 1 54
TABLE 57B
Pkey Unique Eos probeεet identifier number
CAT number Gene cluster number Accession Genbank accession numbers
Pkey CAT Number Accession 417886 1031334.1 AA210987 D57294 AA214584AA207006 D56572 432407 MH1429.12 BG036675 BF772005 BF771866 BG960386 BG960381 NM.005712 AF110315 BE074534 BE182776 BE158000 BE157999 BE714315 AW818104
AW847519 AA099426AW817981 AW856396 BG961122AA224498AA308542 AW821833 BF902155AI732411 BG778834 BG283641 BE748279
BE748870 BG319540 BE748864 BF739224 BG986155 AK057283 BI861466 AA663341 AA457591 BG949294 AW392886 AA071122 AA227849
AA584918 BG959570 BF773486 AL041698 BF959013 R87170 C16859 BF770411 BF771298 A1075321 L13823 AA216700 BF771864 AW861859
BE537068 C18935AA155719 BF771172BF769107 BF804964AW818172AW818143AW392930AW817057AW858044 BF746211 AA179928
AW861687 AW821826 BI055726 BF242643 AA207189 BF770412 BF771157 BG430030 AA055592
434414 35978.1 AF134164 BF809407 AA218567 BF842863 AI267168 BF876178 BG999253 AW861851 AW858362 AI817548 BF771300 AA113928 AA223422
AA055556 BF773400 BF998869 BE081333 BE073424 BE142245 H59571 H59570 BF871558 BF871064 BE001132 BF826831 AW754298
AA223267 BG997895 BG997897 AW991957 AA534354 BG319501 BF736309 AI694265 AA045564 BG950256 AI829309 BG987850 BE093175
BF854337
427298 115241 1 AA933717 BF061897 AW628327 AA641788 AA400495 427521 513212.1 AW973352 BF222929 AW016853 BF059130 AI651829 BE551767 AA558414 AI339359 BF059601 AI961162 AI341422 AI206248 AI206165
AA548736 AA768578 AI539081 AW025957 AA736837 N79575 AW594357 AA480892
407347 810943.1 T23514AI655785 430439 6750.2 AL133561 AL117481 AL122069 AW439292 AI968826 AL041090
TABLE 57C
Pkey Unique number correεpoπdmg to an Eos probeset
Ref Sequence source The 7 digit numberε in thiε column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
402199 8576116 Minus 84187-84744
402680 8113438 Plus 137634-137768,139702-139893,140475-14059
402260 3399665 Minus 113765-113910,115653-115765,116808-11694
402678 8113438 Plus 37395-37514,3786637981
403171 9838164 Minus 74502-74703
406137 9166422 Minus 30487-31058
401704 3097841 Pluε 24712-25374
402677 8113438 Pluε 22135-22309,23063-23238
402679 8113438 Pluε 132079132216
402145 8018280 Pluε 113086114800
406547 7711513 Minus 172780-174358
402398 4092817 Minus 24019-24973
405484 5922025 Plus 199214-199579,199672-199920,200262-20049
401083 3242744 Plus 3319233360
404976 3419864 Minus 139625140632
TABLE 68A 434 genes upregulated in bladder cancer relative to normal body tisεueε
Table 58A lists about 434 genes upregulated in bladder cancer relative to normal body tisεues that are likely to encode proteins amenable to modulation by small molecules, peptides, or antibodies These genes were selxted from 59680 probesets on the Eos/Affymetnx Hu03 Genxhip array Gene expression data for each probeset obtained from this analysis was expressed as average intensity (Al), a normalized value reflxting the relative level of mRNA expression The protein products of these genes often contain one or more domains indicative of have oncogenic function or of transducing mtrxellular signals, or of being moduiatable by small molxules, peptides, or antibodies (e g pkinase, death-domain, 7tm phosphatase, or lon.transporter) Certain predicted protein domains are noted
Pkey Unique Eos probeset identifier number
ExAccn Exemplar xcession number, GenBank xcesεion number
UniGenelD UniGene number
Pred ProtDomams Certain predicted protein domains Abbrevialionε uεed TM, tranεmembrane domain, SS, εignal sequence, =Y, very likely to contain, =M, likely to contain, other protein domain abbreviations are from PFAM (Nucleic Acids Research, 2002, 30276-280)
UniGene Title UniGene gene title
R1 90th percentile of bladder tumor Als divided by the 50th percentile of normal tisεue Als
Pkey, ExAccn, UnigenelD, Unigene Title, Pred ProtDomams, R1
430630, AW269920, Hs 2621, cystatin A (εtefin A), cyεtatιn,TM=M , 3525
422282, AF019225, Hs 114309, apolipoprotein L, MolA_ExbB,TM=Y,SS=M, 33 25
414555, N98569, Hs 76422, phospholipaεe A2, group IIA (platelets, , phoslιp,TM=M,SS=Y, 31 68
415192, D17793, Hs 78183, aldo-keto reductase family 1, member C3 , aldo_keLred,TM=M„ 31 04
417771, AA804698, Hs 82547, retinoic xid rxeptor responder (tazaro, none.none, 2850
439180, AI393742, Hs 199067, v-erb-b2 avian erythroblastic leukemia v, Fuπn lιke,pkιnase,Rxep L_domaιn,Fuπn lιke,pkιnase,Rxep L_domaιn,Peptιdase_M24, 2743
417079, U65590, Hε 81134, interleukin 1 rxeptor antagonist, IL1,SS=M, 2598
413859, AW992356, Hs 8364, Homo sapienε pyruvate dehydrogenase kina, SAM_PNT,noπe, 2538
418818, AA228899, Hs 101307, Homo sapiens HUT11 protein mRNA partial, UT.πone, 25 28
425397, J04088, Hs 156346, topoisomerase (DNA) II alpha (170kD), DNA_gyraεeB,DNA_topoιsolV,HATPaεe_c,SS=M 2358
421733, AL119671, Hs 1420, fibroblast growth factor rxeptor 3 (ach, ig pkιnase,TM=Y,SS=M, 21 24
424008, R02740, Hs 137555, putative chemokine rxeptor; GTP-bmdmg, 7tm_1,TM=Y,SS=M 2045
447343, AA256641, Hε 236894, ESTε, Highly similarto S02392 alpha-2 , none.none, 1978
408243, Y00787, Hs 624, interleukin 8, HLH,PAS,lL8,TM=M„ 1890
427490, Z95152, Hs 178695, mitogen xtivated protem kinase 13, pkιnase,TM=M„ 1875
410687, U24389, Hs 65436, lysyl oxidase-like 1 , Lysyl.oxidase SS=M, 1863
444381, BE387335, Hs 283713, ESTs, Weakly similarto S64054 hypotheti, Collageπ,TM=M SS=M, 1860
452747, BE153855, Hs 61460, Ig superfamily receptor LNIR, ιg,Rhabd_glycop,TM=Y,SS=M, 1855
415444, BE247295, Hs 78452, solute carrier family 20 (phosphate tran, PH04,UM,TM=M , 1825 413132, NM.006823 Hε 75209, protein kinaεe (cAMP-dependent catalyti, PKI,SS=M, 1773 427337, Z46223, Hs 176663, Fc fragment of IgG, low affinity lllb, π ig TM=Y,SS=M, 1768 450746 D82673, Hs 278589, general transcnption factor II, i, none,SH3,PX, 17 12 418945, BE246762, Hs 89499 arachidonate 5-lιpoxygeπase, )ιpoxygenase,PLAT,TM=M„ 1688 5 420981, L40904, Hs 100724, peroxisome proliferative xtivated rxep, hormone.rec.zf C4,TM=M„ 1678
439941, AI392640, Hs 18272, ammo acid transporter system A1, Aa_traπs,TM=Y„ 1675 431846, BE019924, Hs 271580, uroplakin 1B, tranεmembrane4,TM=Y,SS=M, 1656 424247, X14008, Hε 234734, lysozyme (renal amyloidosis), lys,ιg,FAD_Synth ldh,idh_C,pkιnase,SS=M, 1643 414883, AA926960 , CDC28 prote kmase 1, CKS„ 1620 0 438091, AW373062 , nuclear receptor subfamily 1, group I, m, hormone.rec.zf C4,πoπe, 15 80
439963, AW247529 Hs 6793, platelet-activating fxtor acetylhydrola PAF-AH.Ib ϋpase.GDSL TM= , 1570 428450, NM.014791, Hε 184339, KIAA0175 gene product, KA1,pkmaεe,TM=M„ 1563 422278, AF072873, Hs 114218 fπzzled (Drosophila) homolog 6, Fz,Fπzzled,7tm_2,TM=Y,SS=M, 1545 434293, NM.004445, Hs 3796, EphB6, EPH_lbd,fπ3,pkιnase,SAM TM=Y,SS=M, 1543 5 417880, BE241595, Hs 82848, selectm L (lymphxyte adhesion molxule, EGF,lxtιn_c sushι,TM=M,SS=M, 1528
443991, NM.002250 Hs 10082, potasεium intermediate/εmall conductance, CaMBD.SK.channel ιon_trans,TM=Y,SS=M, 15 10 416305, AU076628 Hs 79187, coxsxkie virus and adenovirus rxeptoπ ιg,TM=Y,SS=M, 1490 432306, Y18207, Hs 303090, protein phosphataεe 1, regulatory (mhib, CBM_21,TM=M„ 1480 413076, U10564, Hε 75188, wee1 (S pombe) homolog, pkιnase,TM=M„ 1473 0 429345, R11141, Hs 199695, hypothetical protein, K.teira.SAM, 1458
449230, BE613348 Hs 211579, melanoma cell adheεion molxule, ig ιεodh,Rιbosomal_L6,F-box,TM=Y,SS=M, 14 55 421508, NM.004833, Hs 105115, absent in melanoma 2, PAAD_DAPIN,HIN,TM=M„ 1453 446006, NM_004403, Hs 13530, deafneεε, autoεomal dominant 5, noπe,TM=M,SS=M, 1435 429556, AW139399, Hε 98988, ESTε, noπe,TM=M„ 14 18 5 416224, NM.002902 Hε 79088, reticulxalbm 2, EF-hand calcium bmdin, efhand,SS=M, 1413
429673, AA884407, Hε 211595, protein tyrosine phosphataεe, non recept, Y_phosphatase,Baπd_41,PDZ,SS=M, 1390 426657, NM.015865, Hs 171731, solute carrier family 14 (urea transport, UT,TM=Y„ 1383 428157, AI738719, Hs 198427, hexokmase 2, hexokmase,hexokιnase2,none, 1380
400843, , , NM.003105* Homo sapiens sortilm related, EGF,fn3 ldl_recept.a ldl_rxepLb,granulιn,BNR,TM=Y,SS=M, 1378 O 439453, BE264974, Hs 6566, thyroid hormone receptor mterxtor 13, AAA,ABC_tran,CoaE,TM=M , 1338
432314, AA533447, Hs 312989, ESTs, Xlmk.none 1325 413109, AW389845, Hs 110855, ESTs, PH04,none, 1315 424490, AJ278016, Hs 55565, ankyπn repeat domain 3, ank,pkιnase,TM=M„ 13 13 426490, NM.001621, Hs 170087, aryl hydrocarbon receptor, PAC,PAS,TM=M„ 1293 5 426158, NM 001982 Hs 199067, v erb-b2 avian erythroblastic leukemia v, Fuπn like.pkinase Rxep_L_domaιn,Fuπn like pkιnase,Rxep_L_domaιn Peptιdase_M24, 1243
440249, AI246590, Hs 249175, ESTs, TatD_DNase,pkιnase,death,πoπe, 1238 425177, AF127577, Hs 155017, nuclear receptor interacting protein 1, none,SS=M, 1238 404942, U30825, , splicing fxtor, argmine/seπne πch 9, CD36,TM=Y,SS=M, 1203
439569, AW602166, Hε 222399, CEGP1 protein, EGF NFR c6,granulιn,CUB,Keratιn B2,TIL,TM=M SS=M, 11 93 0 443195, BE148235, Hε 193063, Homo εapiens cDNA FLJ14201 fiε, clone NT, Aajrans none, 11 88
408000, L11690, Hs 198689, bullous pemphigoid antigen 1 (230/240kD), efhand spxtπn,GAS2,SH3,Plectιn,RAXylose_ιsom FlιD,bZIP,Tropomyosιn,Myc-
LZ,M,ldh_C,CH AIP3,TM=M„ 11 88 412182, AA205588, Hs 155160, Splicing fxtor, arginme/seπne πch, 4, rrm,hormone_rx,zf-C4,sugar_tr„ 11 85 433470 AW960564, , transmembrane 4 εuperfamily member 1 , none,TM=Y,SS=M, 11 80 5 425118, AU076611 , Hs 154672, methylene tetrahydrofolate dehydrogenase, myb.DNA bιndιng,THF_DHG_CYH,THF DHG CYH_C,CAP GLY,AAA,LON,Peptιdase_C9,bZIP,M,xan_ur_permeaεe,HC03_cotransp,TM=M„ 11 69 418870, AF147204, Hs 89414, chemokine (C-X-C motif), rxeptor 4 (fus, 7tm_1,7tm.2,TM=Y,SS=M, 11 50 426761, AI015709, Hε 172089, Homo sapiens mRNA, cDNA DKFZp586l2022 (f, πone,TM=Y,SS=M, 11 48 439750, AL359053, Hs 57664, Homo sapiens mRNA full length insert cDN, lMPDH_C,IMPDH_N,CBS,ιntegπn_B,Rιcιn_B_lxtιn, 11 38 0 446742, AA232119, Hε 16085, putative G-protem coupled receptor, none,TM=Y,SS=M, 11 23
436729, BE621807, , traπεmembrane 4 εuperfamily member 1, πone,TM=Y,SS=M, 11 18 409960, BE261944, Hε 339673, hexokmase 1, none.none, 11 02
426539, AB011155, Hs 170290, discε, large (Drosophila) homolog 5, SH3,PDZ,Guanylate_kιn,TM=M„ 1078 417821, BE245149, Hs 82643, protein tyrosine kinase 9, cofiliπ ADF,SS=M, 1063 5 427654, AA410183, Hs 137475, ESTs, ιon_trans,vwc,IGFBP,tsp_1, 1058
418004, U37519, Hε 87539, aldehyde dehydrogenase 3 family, member , aldedh,TM=M,SS=M, 1053 447365, BE383676, Hε 334, Rho guanine nucleotide exchange fxtor (, SH3,PH,RhoGEF,TM=M„ 1053 449437, AI702038, Hε 100057, Homo εapienε cDNA FU22902 fis, clone K, none.none, 10 52 436856, AI469355, Hs 127310, ESTs, pkιnase,rrm,TM=M„ 1048 0 451035, AU076785, Hε 430, plastm 1 (I isoform), efhand,CH,Adaptm_N,SS=M, 1038
418299, AA279530, Hε 83968, integnn, beta 2 (antigen CD18 (p95), ly, integπn B,EGF,PSI,TM=Y,SS=M, 1035 431890, X17033, Hε 271986, integnn, alpha 2 (CD49B, alpha 2εubuπι, vwa,ιntegπn_A,FG-GAP,TM=Y,SS=M, 1034 440006, AK000517, Hε 6844, hypothetical protein FLJ20510, AAA.NB ARC,PAAD_DAPIN,NA,NA, 10 25 420344, BE463721, Hε 97101, putative G protein-coupled rxeptor, Methyltransf 5,TM=Y,SS=M, 10 18 5 437852, BE001836, Hs 256897, ESTs, Weakly similar to dJ365012 1 [H sa, GPS,7tm_2,TM=Y„ 10 13
400752, , , NMJ03105* Homo sapiens sortiiin-related, EGF,fn3,ldl_rxepLa ldl_rxepLb,granulιn,BNR,TM=Y,SS=M, 1008 427700, AA262294, Hs 180383, dual specificity phosphatase 6, Rhodanese,DSPc,TM=M„ 1005
426728, NM 007118, Hs 171957, triple functional domain (PTPRF interact, SH3,ιg,pkιnase,PH,spxtππ,RhoGEF,TM=M„ 1005 400496, , , ENSP00000224716* GTP-bindmg protein SAR, none,TM=Y„ 1001 0 413899, AF083892, Hs 75608, tight junction protein 2 (zona xoludens, SH3,PDZ,Guanylate_kιπ,TM=M„ 1000
404568, , , NM_022071* Homo sapienε hypothetical pro, SH2,TM=M„ 1000 444823, BE262989, Hε 12045, putative protein, Mra1,MBOAT,TM=M,SS=Y, 993 421425, AK001564, Hs 104222, hypothetical protein FU10702, efhand.kazal.arf raε,7tm_1,TM=M„ 990 413441, AI929374, Hs 75367, Src like-adapter, SH2,SH3,TM=M„ 990 75 424954, NM.000546, Hs 1846, tumor protein p53 (Li Fraumeni syndrome), P53,WD40,IRK,TM=M„ 988
452289, BE568205, Hs 28827, mitogen-xtivated protein kmase kinaεe , pkmase,TM=M„ 985 439223, AW238299 Hs 250618, UL16 binding protein 2, ldl_rxept_a,PKD,MHCJ,TM=M,SS=Y, 983 429238, NM.002849, Hs 198288, protein tyrosine phosphataεe, rxeptor t, Y_phoεphataεe,TM=Y,SS=M, 980 _ . 414135, NM.004419, Hε 2128, dual εp cificity phoεphatase 5, Rhodanese,DSPc,Y_phoεphatase,TM=M„ 973
80 452239, AW379378, Hs 170121, protein tyrosine phosphatase, rxeptor t, none.none, 973
418322, AA284166, Hs 84113, cyclm-dependent kmase inhibitor 3 (CDK, Y phosphatase.DSPc TM=M„ 972
403912, , , C5000394* gι|12737280|reflXP_0066822| k, none,TM=M„ 970
427315, AA179949 Hs 175563, Homo sapiens mRNA, cDNA DKFZp564N0763 (f, none,spxtπn,SH3,PH,CH, 970 428428, AL037544, Hs 184298, cyclm-dependent kinase 7 (homolog of Xe, pkιnase,TM=M„ 968 422241, Y00062, Hs 170121, protein tyrosine phosphatase, rxeptor t, kmesm,fn3,Y_phosphataεe,TM=M„ 963 429083, Y09397, Hs 227817, BCL2-related protein Al, Bcl-2,TM=M„ 963
425322, U63630, Hs 155637, protein kmase, DNA-xtivated, catalytic, PI3_PI4_kιnase,FAT,FATC,TM=M„ 955 5 430259, BE550182, Hs 127826, RalGEF-like protein 3, mouse homolog fπ3,RA,RaεGEF,TM=M,SS=M, 950
428520, AA331901, Hs 184736, hypothetical protein FLJ10097, none,TM=M„ 950 418969, W33191, Hs 28907, hypothetical protein FLJ20258, SH3,TM=M„ 950
448913, AA194422, Hs 22564, myosin VI, rrm,zf-RanBP,pkιnase,GST C,Ets,SAM_PNT,ABC2_membrane,myosιn head,IQ,Myosιn_N,bZIP,zf- C2H2,PHD,BTB,TFIIS,AT_hook,SAM,TM=M„ 950 0 414911, NM.000107, Hs 77602, damage-specific DNA binding protein 2 (4, WD40,homeobox,LIM,TM=M„ 948
451295, AI557212, Hs 17132, ESTs, Moderately similarto I54374 gene , pkιnaεe,DAG_PE-bmd,pkιπaεe_C,OPR,πone, 945 402328, , , Target Exon, pkιπase,TM=M„ 944
443710, AI928136, Hs 9691, Homo sapienε cDNA FLJ23249 fiε, clone C, G-alpha,none, 942 414987, AA524394, Hs 294022, hypothetical protein FLJ14950, SH2,TM=M„ 942 5 434375, BE277910, Hs 3833, 3'-phosphoadeπoειne δ'-phoεphosulfate sy, APS kιnase,ATP-sulfurylaεe,PRK,Thymιdylate km,SS=M, 940
418827, BE327311, Hs 47166, HT021, none,TM=M„ 940
440675, AW005054, Hε 47883, ESTs, Weakly similar to KCCLHUMAN CALCI, pkinase.none, 935 433376, AI249361, Hs 74122, caspase 4, apoptosis-related cysteine pn CARD,ICE_p10,ICE_p20,SS=M, 928 410668, BE379794, Hs 65403, hypothetical protein, dealh,TNFR_c6,TM=Y,SS=M, 925 0 430024, AI808780, Hs 227730, integnn, alpha 6, ιntegrιπ_A,FG-GAP,TM=Y,SS=M, 923
452696, AI826645 Hs 211534, ESTs, ArfGap,PH,aπk,Guaπylate_km,PDZ,SH3, 9 13 434263, N34895, Hs 44648, ESTs, ig.none, 913
407949, W21874, Hs 247057, ESTε, Weakly similarto 2109260A B cell , RιbosomaI_S14,aπk,pkιnase,death,none, 910 429332, AF030403, Hs 199263, Ste-20 related kmase, pkmase,metalthιo,TM=M,SS=M, 908 5 417426, NM.002291, Hs 82124, laminin, beta 1, lamιnιn_EGF,lamιnm_Nterm,ιntegπn_B,SS=M, 908
443951, F13272, Hs 111334, ferπtin, light polypeptide, PMP22_Claudιn,πone, 907 414368, W70171, Hs 75939, undine monophosphate kinase, PRK.CoaE,, 898 451292, AB037716, Hs 26204, KIAA1295 protein, SH3,TM=M„ 893 438000, AI825880, Hs 5985, πon-kmase Cdc42 effector protein SPEC2, none,TM=M„ 890 O 446620, AA128808, Hs 179902, transporter-like protein, none,TM=Y,SS=M, 890
436075, BE090176, Hs 179902, transporter-like protein, none,TM=Y,SS=M, 888 437056, AH 47061, , gb ok33a11 ε1 Soares_NSF_F8_9W.OT_PA.P_S, none,spectrm,SH3,PH,CH, 878 445496, AB007860, Hs 12802, development and differentiation enhancin, SH3,ank,PH,ArfGap,TM=M , 878 418203, X54942, Hs 83758, CDC28 protein kinase 2, CKS„ 875 5 434608, AA805443, Hs 179909, hypothetical protein FLJ22995, none,TM=M„ 870
445033, AV652402, Hs 72901, mucin 13, epithelial transmembrane, ank,, 868 417640, D30857, Hs 82353, protein C rxeptor, endothelial (EPCR), none,TM=M,SS=M, 865 432841, M93425, Hs 62, protein tyrosine phosphatase, non rxept, Y_phosphataεe,SS=M, 865 430397, AI924533, Hs 105607, bicarbonate transporter related protein , HC03_cotransp,TM=Y„ 864 0 448888, AW196663, Hε 200242, caspase recruitment domain protein 6, CARD,TM=M„ 860
442994, AI026718, Hs 16954, ESTs, aπk,pkmase,death,Rιbosomal_S14, 860 429109, AL008637, Hs 196352, neutrophil cytosolic fxtor 4 (40kD), SH3,OPR,PX,TM=M„ 860 455439, AW945484, Hε 184252, ESTs, Weakly similar to ALU8_HUMAN ALU S, none,7tm_1 , 855 437763, AA469369, Hs 5831, ussue inhibitor of metalloprotemase 1 , TIMP,pkιnase,DAG_PE-bιnd,RBD, 843 5 417035, AA192455, Hs 22968, Homo sapienε clone IMAGE 451939, mRNA se, none.none, 840
418478, U38945, Hs 1174, cyclm-dependent kinase inhibitor 2A (me, ank,, 839 448209, AW160489, Hs 20709, tetraspaπ 5, transmembrane4,TM=Y,SS=M, 833 450139, AK001838, Hs 296323, serum/glucxorticoid regulated kinase, none.none, 833 445350, AF052112, Hs 12540, lysophospholipaεe I, abhydrolase_2,TM=M„ 831 0 427509, M62505, Hs 2161, complement component 5 rxeptor 1 (C5a 1, 7tm 1,TM=Y,SS=M, 830
445633, AI453386, Hs 17287, ESTs, Weakly similar to S26689 hypotheti, IRK.none, 828 446719, W39500, Hs 301872, hypothetical protein MGC4840, AAA,SKI,TM=M„ 823 424762, AL119442, Hs 183684, eukaryotic translation initiation fxtor, none.none, 820 427274, NM.005211, Hs 174142, colony stimulating factor 1 rxeptor, fo, ιg,pkιnase,TM=Y,SS=M, 818 5 416094, AW995512, Hs 225977, nuclear rxeptor coxtivator 3, none.none, 815
419262, AA834664, Hs 29131, nuclear rxeptor coxtivator 2, PAS,zf-C2H2,SET, 815 417386, AL037228, Hs 82043, D123 gene product, NUDIX,sxY,E1_dehydrog,tranεket_pyr,TM=Y,SS=M, 813 431236, AV656840, Hs 285115, interieukin 13 rxeptor, alpha 1, fn3,TM=Y,SS=M, 810 439658, AA332057, Hs 6639, hypothetical protein MGC15440, noπe,TM=M,SS=M, 809 0 425424, NM.004954, Hs 157199, ELKL motif kinase, pkιnase,UBA,KA1,TM=M„ 808
422573, AW297985, Hε 295726, integnn, alpha V (vitronxtm rxeptor, FG-GAP,ιntegπn_A,none, 805 408912, AB011084, Hs 48924, KIAA0512 gene product, ALEX2, ArmadιIlo_seg,TM=M,SS=M, 803 447674, BE270640, Hs 19192, cyclm-dependent kinase 2, pkιπase,SS=M, 803 404891 , , , Target Exon, none.none, 795 5 414278, AA330116, Hs 77273, Human glucose transporter pseudogene, none.none, 793
452888, AW955454, Hs 30942, ephπn-B2, Ephπn,fπ2,TM=Y,SS=M, 793 433211, H11850, Hs 12808, MARK, pkιnase,UBA,KA1,SS=M, 791 438485, W57578, Hs 237955, RAB7, member RAS oncogene family, pkinase,ABC1,πone, 790 413219, AA878200, Hs 118727, Homo εapienε cDNA FLJ13692 fiε, clone PL, HLH,death,TNFR_c6,Acyl-CoA_hydro, 790 0 417381, AF164142, Hs 82042, solute earner family 23 (nucleobase tra, xaπ_ur permease.RA, 788
427122, AW057736, Hs 323910, HER2 rxeptor tyrosine kinase (c-erb-b2„ Fuπn-lιke,pkιnase,Rxep_L_domain,YLP,TM=Y,SS=M, 786 405036, , , NM.021628* Homo sapiens arxhidonate lip, lιpoxygenase,complex1_49Kd,PLAT,TM=M„ 783
418529, AW005695, Hs 250897, TRK-fused gene, Band_41,ERM,pkιnase,LRR,LRRCT,MAM,Nucleoplaεmιn,Tropomyoεm,OPR,filament,bZIP,G-gamma,M,DUF164,TM=M„ 783 431912, AI660552, Hs 76549, ESTs, Weakly similar to A56154 Abl subst, none,Acyl-CoA_dh,Acyl-CoA_dh M,Acyl-CoA dh.N, 780 / 5 432981 , NM.002733, Hε 3136, protein kinaεe, AMP-activated, gamma 1 n, CBS,Aa_traπs,TM=M„ 778
422940, BE077458, , gb RC1-BT0606090500-0154)04 BT0606 Homo, Sec7,PH,ANF_rxeptor,!ιg_chan,WD40,IRK, 778 446636, AC002563, Hs 15767, citron (rho-interacting, seππe/thrxnm, CNH,DAG_PE-bιπd,PH,lnvolucπn,M,TM=M„ 778 431183, NM.006855, Hε 250696, KDEL (Lyε-Asp-Glu-Leu) endoplasmic retic, ER_lumen_rxept,TM=M,SS=M, 778 400845, , , NM_003105* Homo sapiens sortilm-related, EGF,fπ3,ldl recept_a,ldl_rxept_b,granulιπ,BNR,TM-Y,SS-M, 773 80 409142, AL136877, Hs 50758, SMC4 (structural maintenance of chromoso, ABC_tran,M,SMC_N,SMC_C,DUF164,noπe, 773
437192, AW975786, Hs 75355, ubiquihn-conjugating enzyme E2N (homolo, UQ_con,Y phosphatase,SH2, 770 403212, , , NM.019595 Homo sapiens intersxtiπ 2 (IT, SH3,efhand,C2,PH,RhoGEF,TM=M„ 770 441190, H09073, Hs 25046, ESTs, E1-E2_ATPase,Catιon_ATPase_C,Catιon.ATPase_N,Hydrolase,none, 768 409745, AA077391 , gb 7B14E12 Chromosome 7 Fetal Brain cDNA, 7tm_1,zf-C3HC4,fn3,SPRY,KRAB,zf C2H2 rve zf B_box,TM=Y,SS=M, 768 428840, M15990, Hs 194148 v-yes-1 Yamaguchi sarcoma viral oncogene, SH2,SH3,pkmase,SS=M, 765 447898, AW969638, Hs 112318, 62 kd protem, none none, 765
425289, AW139342, Hs 155530, interferon, gamma inducible protein 16, PAAD_DAP!N,HIN,SS=M, 763 401927, , , C17000914* gι|8394367|ref|NP_0585491| s, none,, 760
407347, AA829847, , gb od40d07 s1 NCI_CGAP_GCB1 Homo sapiens, RhoGAP,SH2 pkιπase,POLO_box,πone, 758 449924, W30681, Hs 146233, Homo sapienε cDNA FLJ22130 fis, clone H, SH3,none, 757
429952 AF080158, Hs 226573, inhibitor of kappa light polypeptide gen, pkιnase,ubιquιtιn,Enterotoxιπ_A,PH04,pkmase,ubιquιtιπ, 755 445800 AA126419, Hs 32944 mositol polyphosphate 4-phoεphatase, ty, none none, 755 421489, AI922821, Hε 32433, ESTε πone.PI PLC-X,PI-PLC-Y,C2, 753
430486, BE062109, Hε 241551, chloride channel, calcium xtivated, fa , none TM=Y,SS=M, 753 431605 AW972407, Hs 124370, gb EST384498 MAGE resequences, MAGL Homo, adenylatekιnase,SRP54,TM=M„ 750 430570, AI417881, Hs 292464, ESTs, 7lm_2,Fz,Fπzzled,πone, 750 431441, U81961, Hs 2794, sodium channel noπvoltage-gated 1 alpha ASCTM=Y„ 748 420676, AI434780, Hs 4248, vav 2 oncogene, RhoGEF,PH,CH,SH2,SH3,DAG_PE-bmd,none 748
444252, R21135, Hs 54985 ESTs, none.none, 747
414914 U49844, Hs 77613, aiaxia telangiectasia and Rad3 related, FAT.FATC PI3_PI4_kιnase,TM=M„ 747 443426 AF098158, Hs 9329, chromosome 20 open reading frame 1, noπe,TM=M„ 745 418546, AA224827, , gb nc32g04s1 NCI.CGAP Pr2 Homo sapiens , vwa,ιntegπn_A,FG-GAP,none, 745 437860 AA333063, Hs 279898 Homo sapiens cDNA FLJ23165 fis, clone L, πone.NA NA 743
452007, AA426234, Hs 34906, ESTs, Weakly similar to T17210 hypotheti, none.pkinase, 740 432407, AA221036, , gb zr03f12 r1 Stratagene NT2 neuronal pr, DEAD,he!ιcase_C,rrm,Ndr,Cys_knot,TIL,vwa vwc,vwd,IQ,Rlla,abhydrolase,TGF- beta,DUF139,TPR,DSPc,tsp_1,Rιbosomal_S21,rvp,TM=M„ 740 424943 AU077260, Hs 153924, death-ass∞iated protein kinase 1, aπk,pkιnase,death,SPRY,SAP,Rιbosomal_L24e,SRP54,dDENN,DENN,uDENNTM=M„ 740 421429, NM.014922, Hs 104305, death effector filament-forming Ced-4-lι, LRR PAAD_DAP|N,AAA,CARD,NB ARC.NA.NA, 738
417141, U22662, Hs 347353, nuclear rxeptor subfamily 1, group H, m, hormoπe.rx.zf C4,SS=M, 738 430016, NM.004736, Hs 227656, xeπotropic and polytropic retrovirus rx, SPX,EXS,TM=Y„ 738 422813, AV656571, Hε 121068 transmembrane 4 superfamily member 6, transmembraπe4,TM=Y,SS=M, 732 433390 AA586950, Hs 260180 Homo sapiens mRNA, cDNA DKFZp761G18121 (, none.εpxtππ SH3,PH,CH, 725 409213, U61412, Hs 51133, PTK6 protein tyrosine kinase 6, SH2,SH3,pkιπase,TM=M„ 724
444745, AF117754 Hs 11861, thyroid hormone rxeptor-assxiated prot, none,TM=M„ 723 452817, AA322859, Hs 284275 Homo sapiens PAK2 mRNA, complete eds, pkιnase,PBD,TM=M„ 7 19 407591, NMJ00910, Hs 37125 neuropeptide Y rxeptor Y2, 7tm_1,TM=Y„ 718 427231, AW851989, Hs 285814 sprouty (Drosophila) homolog 4, SH2,SH3,TM=M,SS=M, 718 450285, AW383256, Hε 24752, εpxtπn SH3 domain binding protein 1, SH3,TM=M„ 7 18
403344, , , NM.000341 Homo εapiens solute earner fa alpha amylase,TM=Y„ 715 427268, X78520, Hs 174139, chloπde channel 3, CBS,voItage_CLC,TM=Y„ 714 442213, N36110, Hs 305971, solute carrier family 2 (facilitated glu, sugar_tr;TM=Y,SS=M, 7 14 404875, , , NM 022819* Homo εapienε phoεphoiipaεe A2, phoslιp,SS=M, 7 11 433618 AA602539, Hs 345494, ESTs, G-alpha,A_deammase, 7 10
417165, R80137, Hε 302738, Homo εapienε cDNA FLJ21425 fiε, clone C, Sulfate.transp STAS.HMG.box, 708 413073, AL038165, Hs 75187, traπslxase of outer mitxhondπal membr, MAS20,zf A20,VPS9,TM=M,SS=M, 705 426655 AL049589, Hs 171723, neuronal cell death-related protein, TFIID-31,TM=M„ 705 423387, AJ012074, , vasoxtive intestinal peptide receptor 1, 7tm_2,HRM,CSD,TM=Y,SS=M, 703 400211, , , NM.003899* Homo sapiens PAK-interxtmg , SH3,PH,RhoGEF,Terpene_synth,TM=M„ 703
438150, AA037534, Hs 342874, transforming growth fxtor, beta rxepto, zona_peIlucιda,noπe, 693 431341, AA307211, Hs 251531, proteasome (prosome, macropain) subunit,, proteasome,TM=M„ 693 405275, AB028989, , mitogen xtivated protein kinase 8 inter, Cys_kπot,TGF-beta,vwa vwc,vwd,TIL,DUF139,SS=M, 693 415392, Z44067, Hε 10957, ESTs, PIP5K,noπe, 689 429355, AW973253, Hs 292689, ESTs, pkmase,bZIP,Armadιllo_seg,πone, 688
429663, M68874, Hs 211687, phospholipase A2, group IVA (cytosolic, , C2,PLA2_B,TM=M„ 685 427832, AF038362, Hε 180930, TBP-assxiated factor 172, SNF2_N,helιcase_C Armadιllo_seg,HEAT,TM=M„ 683 447887, AA114050, Hε 19949, caεpase 8, apoptosiε-related cyεteine pr, ICE_p10,ICE_p20,DED,TM=M„ 680 400158, , , ENSP00000244302* CDNA FU11591 fis, cion, Sm,SS=M, 678 401917, AL050149, , RAN binding protein 3, Orexιπ,SH2,STAT,STAT_bιπd,STAT_prot,ιon_traπs,PAC,PAS,noπe, 678
400844, , , NM_003105* Homo εapienε sortilm-related, EGF,fπ3,ldl_rxepLa Id l_recept_b,granulιπ,BNR,TM=Y,SS=M, 673 457238, U07358, Hs 211601, mitogen xtivated protein kinase kmase , pkinase,, 673 404440, , , NM.021048 Homo sapiens melanoma antigen,, MAGE,TM=M„ 673 424241, AW995948, Hs 182339, Homo sapiens pyruvate dehydrogenase kma, Ets,SAM_PNT,TM=M„ 670 426746, J03626, Hs 2057, uπdme monophosphate synthetase (orotat, Pnbosyltraπ,OMPdxase,TM=M„ 670
429429, AA829725, Hs 334437, hypothetical protein MGC4248, noπe,transmembrane4, 665 450825, AC005954, Hs 25527, tight junction protein 3 (zona xcludens, PDZ,Guanylate km,SS=M, 664 408638, AW451353, Hε 173328, ESTε, B56,none, 663 408056, AA312329, Hε 42331, ephπn A4, Ephπn,TM=M,SS=M, 661 401057, BE563196, , eukaryotic translation elongation fxtor, ιon_trans,IQ,TM=Y„ 660
446526, H89616, Hs 296290, Homo sapienε cDNA FLJ13357 fiε, clone PL, none.none, 660 400528, , , NM.020975* Homo εapienε ret proto-oncoge, cadheπn,pkιnase,TM=Y,SS=M, 658 418562, R60669, Hs 124831, CGI-67 protein, none,Skp1,AAA, 657 453826, AL138129, , gb DKFZp547F152_r1 547 (synonym hfbrl) , PK,PK_C,noπe, 655 437412, BE069288, Hs 34744, Homo εapieπε mRNA cDNA DKFZp547C136 (fr; ABC_tran,GTP_EFTU,ABC_membraπe,noπe, 654
415088, AI077288, Hε 296323, εerum/glucxorticoid regulated kinaεe, none.none, 650
453489, AA300067, Hs 33032, hypothetical protein DKFZp434N185, F5_F8_type_C,pkιnase,Ets,F5_F8_type_C,pkmase,Etε, 647 439866, AA280717, Hε 6727, Raε-GTPase xtivatmg protein SH3 domain rrm NTF2,TM=M„ 646 456376, AA663904, Hε 89862, TNFRSF1A asεociated via death domain, dealh,TM=M„ 646 441712, AW391927, Hε 7946 KIAA1288 protein, AIP3,TM=M„ 644
414557, AA340111, Hε 100009, xyl Coenzyme A oxidaεe 1, palmitoyl, pkmaεe,7tm_1, 643 432211, BE274530, Hs 273333, hypothetical protein FLJ10986, FGGY_C,TM=M„ 643 432945, AL043683, Hs 8173, hypothetical protein FLJ10803, noπe,TM=M,SS=M, 640 438941, AF075047, Hs 31864, ESTs, Ca_chanπel_B,SH3,arf,none, 640 441466, AW673081, Hs 54828, ESTε, pkιnaεe,zf-C2H2 KRAB.none, 633
438698, AW297855, Hε 125815, ESTε, Weakly similarto I38022 hypotheti, lιpoxygenase,PLAT,noπe, 6 33 433255, AI274270, Hs 96840, KIAA1527 protein, MHCK_EF2_kιnase,TM=M,SS=M, 633 427801, AW979155, Hs 298275, ammo xid transporter 2, Aajrans TM=M,SS=M, 632 407970, AW403814, Hs 41714, BCL2-assxιated athanogene, ubιquιtιn,BAG,Tropomyosm„ 630 438464, AA669735, Hs 324743, protein phosphatase 4 regulatory subunit, none.none, 630 453977, AA886006, Hε 250427, ESTε, pkιnaεe,P2X_receptor,E1 E2_ATPaεe,Hydrolase, 630 412491, W31589, Hs 73957, RAB5A, member RAS oncogene family, ras,arf,PP2C,TM=M„ 630 413235, BE243445, Hs 75248, topoisomerase (DNA) II beta (180kD), DNA_gyraseB,DNA_topoιso!V,HATPase_c,DNA_gyraseB,DNA topoisolV.HATPase.c, 629
404342, , , C7002192* gι|7299207|gb|AAF54404 1| (AE0, none,TM=M„ 627 409274, NM 003930, Hs 52644 SKAP55 homologue, SH3,PH,SS=M, 625
419693, AA133749, Hs 301350, FXYD doma -conlamiπg ion transport reg, ATP1G1_PLM_MAT8,TM=Y,SS=M, 623 405429, , , Target Exon, Y_phosphatase,none, 623 404975, AL042279, , uncharxteπzed hypothalamus protein HT0, kπngle,TM=Y,SS=M, 620 452929, AW954938, Hs 172816, πeuregulin 1, Neuregulιπ,EGF,ιg,Neuregulιπ,EGF,ιg, 6 18 446883, AW452756, Hs 16364, hypothetical protein FLJ10955, DEAD,helicase_C,rrm,Ndr,Cys_knot,TIL,vwa,vwc,vwd,IQ,Rlla,abhydrolase,TGF- beta,DUF139,TPR,DSPc,tεp 1,Rιbosomal S21,rvp,TM=M„ 6 18 433233, AB040927, Hs 301804, KIAA1494 protein, SH3,zf-C3HC4,TM=M„ 6 15 458791, BE615453, Hs 346509, dedicator of cyto-kinesiε 1, πone,TM=Y„ 6 15
421836, AF109219, Hs 108787, phosphatidylmoεitol glycan, class N, none.none, 6 14 447727, AI421079, , tumor necroεiε fxtor rxeptor εuperfami, none.synaptobrevin, 6 13 401536, , , NM.002530* Homo sapiens neurotrophic tyr, ιg,pkιnase,LRR,LRRNT,LRRCT,TM=M,SS=M, 6 11
444317, AI140566, Hs 143436, ESTε, Weakly similar to PLHU plasmin [H , PAN,kπngle,tιypsιπ,PI-PLC-X,C2,SH2,PH,SH3,PI-PLC-Y,PAN, 6 10 427557, NM.002659, Hs 179657, plaεminogeπ xtivator, urokmase rxepto, UPAR LY6,ET,PLA2_mh,SS=M, 6 08 450447, AF212223, Hs 25010, hypothetical protein P15-2, NTF2,TM=M„ 608 450107, AI873287, Hs 257812, ESTs, ICE_p20,DED,TM=M„ 605
418175, AW967054, Hs 206312, ESTs, Weakly similar to I38022 hypotheti, zf-C2H2,BTB,K_tetra,Syπtaxιn,noπe, 605 408983, NM.000492, Hs 663, cystic fibrosis transmembrane conductanc, ABC_tran,ABC_membrane,PRK,Bx_export_3,TM=Y„ 605 439738, BE246502, Hs 9598, sema domain, immunoglobulin domain (lg)„ Sema,PSI,ιπtegπn_B,TM=Y„ 603
427625, AF008216, Hs 285013, putative human HLA clasε II associated p, none.none, 603 409430, R21945, Hs 346735, splicing factor, argmine/seπne-πch 5, DSPc.Rhodanese.none, 603 446650, AB016625, Hs 15813, εolute earner family 22 (organic cation, εugar.tr,TM=Y,SS=M, 603 405102, , , C15001220* gι|4469558|gbl,AAD21311 1| (AF, DAG_PE-bind,PH,RhoGEF,DC1,SS=M, 603 400121, , , Eos Control, SH3,PH,RhoGEF,Terpeπe εynth,TM=M„ 603
415327, H22769, , gb ym54c02 r1 Soares infant brain 1 IB H, SH3,PDZ,Guanylate_kιn,SS=M, 603 404148, , , NM.002944* Homo sapiens v-ros avian UR2 , fn3,pkιnaεe,DUF139,TM=Y,SS=M, 603 405531, , , Target Exon, PDZ,CARD,Guanylate_kιn,TM=M„ 600 433363, AA584829, Hs 275163, πon-metastatic cells 2, protein (NM23B) , NDK.none, 600 427270, H47921, Hs 174139, chloride channel 3, voltage_CLC,CBS,πoπe, 599
423774, L39064, Hs 1702, interleukin 9 rxeptor, none,TM=M,SS=M, 5 98 424124, AA335609, Hs 7589, ESTs, Weakly similar to A46010 X-lmked , pkmase.TBC, 598 411040, AF007393, Hs 177574, protein k ase, interferoπ-inducible dou, HLH,TM=M„ 595 423422, AC005175, Hs 128425, NY-REN-24 antigen, Sulfotransfer,7tm 1,none, 588 453902, BE502341, Hs 3402, ESTs, none.none, 588
409636, AA305729, Hs 18272, ammo xid transporter syεtem A1, Aa_trans,TM=Y„ 586 436154, AA764950, Hs 119898, ESTs, efhand,DAG_PE-bmd,DAGKa,PHD,DAGKc,PSI,πone, 585 455358, AW902641, , gb QV3-NN1024-100500-181-d08 NN1024 Homo, SuIfatase,Somatomedιn_B,Phoεphodιest,πone, 583 414108, AI267592, Hs 75761, SFRS protem kinase 1, ank,PH,Oxysterol_BP,pkιπaεe,TM=M„ 582 452547, AA335295, Hs 74120, adipose spxific 2, LEA,TM=M„ 582
415204, T27434, , gb hbc2294 Human pancreatic islet Homo s, Na.Ca Ex, Calx-beta, none, 580 435563, AF210317, Hs 95497, solute earner family 2 (facilitated glu, sugar_tr,TM=Y„ 578 456097, C15702, Hε 288028, ESTε, Moderately similar to I54374 gene , dsrm.FKBP, 578
422445, M23114, Hε 1526, ATPase, Ca transporting, cardix muscle,, E1-E2 ATPase,Catιon_ATPase C,Catιon_ATPase_N,HydroIaεe,TM=Y„ 577 436246, AW450963, Hs 119991 , ESTε, noπe.DNA _gyraseB,DNA_topoiεolV,HATPase_c, 575
422953, AA488860, Hs 245043, hypothetical protein FLJ14297, ABC tran,PRK,TM=Y,SS=M, 575 425854, AA749190, , ESTs, RhoGAP,SH2,pkιnase,POLO_box,noπe, 574 424160, T74062, , gb yc81f01 r1 Soares infant brain 1 NIB H, ROK,none, 570 417389, BE260964, Hs 82045, midkme (neuπte growth-promoting fxtor; PTN MK,TM=M,SS=Y, 569 437613, R19892, Hε 10267, MIL1 protein, none.none, 5 68
410820, BE391493, Hε 16475, Human DNA εequence from clone RP5-852M4 , TBC,SS=M, 568 423393, R37772, Hε 21420, p21-xtιvated protein kinase 6, pkιnase,PBD,TM=M„ 566 426500, NM.014638, Hs 170156, KIAA045O gene product, C2,PI-PLC-Y,TM=M„ 563 406930, U04691, , gb Human olfxtory rxeptor (OR17-219) g, none,TM=Y,SS=M, 560 401044, , , Target Exon, none,ICE_p20,ICE_p10,CARD,Peptιdase_M1, 5 56
428479, Y00272, Hs 334562, cell division cycle 2, G1 to S and G2to, pkιnase,ICE_p10,ICE_p20,TM=M,SS=M, 555 421970, AF227156, Hε 110103, RNA polymerase I transcnption fxtor RR, aa_permeaseε,pyπdoxa!_deC,bromodomaιn,PHD,MBD,AT hook,DDT,PI3 PI4 kιnaεe,FAT,FATC,BolA,RUN,TM=M„ 5 53 426248, T18988, Hε 293668, ESTs, pkinase.none, 550 418426, NM 03804, Hs 296327, rxeptor (TNFRSF)-ιπterxtιng seππe-thr, pkιπase,death,TM=M„ 543
417086, AA194446, , ESTs, Weakly similar to S55024 nebulm, , ank,death,ZU5,EGF,kπngle,trypsm,Nebulιn,LIM,SS=M, 543 447437, U07225, Hε 339, puπnergio rxeptor P2Y, G-protein coupl, 7tm_1,SH2,TM=Y,SS=M, 540 412247, AF022375, Hε 73793, vascular endothelial growth fxtor, PDGF,SS=M, 540
434938, AW500718, Hs 8115, Homo sapiens, clone MGC 16169, mRNA, com, pkιnase,TBC,Rhodaneεe,TM=M„ 538 419355, AA428520, Hε 90061, progeεterone binding protein, heme_1,TM=Y,SS=M, 535
411188, BE161168, , gb PMO-HT0425-170100-002-a10 HT0425 Homo, adenylatekinaεe.noπe, 535 422461, NMJ03417, Hs 117077, zinc finger protein 264, zf-C2H2,KRAB,TFIIS,TM=M„ 528 426348, BE466586, Hs 17433, hypothetical protein FLJ20967, none.none, 5 25
429170, NMJ01394, Hs 2359, dual specificity phosphatase 4, Rfιodanese,DSPc,Y_phosphatase,Rιbosomal_S3_N,TM=M„ 5 23 429592, AB029041 , Hs 209646, KIAA1118 protein, Troponm,Exo_endo_phos,IQ,TM=M„ 522
434821 , AA159111 , Hs 284281 , Human putative πbosomal protein S1 mRNA, ER_lumeπ_rxept,Rιbosomal_L11 ,Rιbosomal_L11_N,TM=Y,SS=M, 521 434368, AW519020, Hs 73893, dopamme receptor D2, pkιπase,SH3,none, 5 15 405586, , , NM.000299 Homo εapieπs plakophilin 1 (x, Armadιllo_seg,TM=M„ 5 13 408176, AK001553, Hs 43436, adenylate kinase 3 alpha like, adenylatekinaεe.noπe, 512 407443, AF227138, , gb Homo εapienε candidate taste rxeptor, none,TM=Y,SS=M, 5 11 416817, AA398045, Hs 104679, ESTs, Fuπn-lιke,pkιπase,Recep_L_domaιn,fn3,noπe, 5 10 401886, , , NMJ21783 Homo sapienε XEDAR (XEDAR), mR, TNFR_c6,TM=M,SS=M, 508 410314, AW860708, Hε 18851, hypothetical protein FLJ10875, myb_DNA-bιndιng,PAH,BAH,bromodomaιn,PHD,SET,TM=M„ 508 401579, AL031447, , Homo εapienε, clone IMAGE 4053044, mRNA,, Neur.chaπ.LBD.Neur.chaπ.memb.πone, 505 445873, AA250970, Hε 251946, poly(A)-bιndιng protein, cytoplaεmic 1-1, PABP,rrm,pkmaεe,14-3-3, 505 417529, AA203634, , gb zx58b09 r1 Soares.fetal.liver.spleen., pkιnase,UBA,KA1,none, 503 417527, AA203524, , gb zx56e10 r1 Soares.fetal.liver.εpleen., SH3,SS=M, 498 407722, BE252241, Hs 38041, pyπdoxal (pyπdoxme, vitamin B6) kinaε, pfkB,TM=M„ 496
431321, AW136372, Hε 1852, xid phosphatase, prostate, xιd_phosphat,πoπe, 493 404298, , , C6001238* gι|121715|sp|P26697|GTA3_CHICK, none,GST_C,GST_N,pkιnase, 485 407603, AW955705, Hs 62604, Homo sapienε, clone IMAGE 4299322, mRNA,, none,TM=M„ 482 424099, AF071202, Hs 139336, ATP-bmding cassette, sub family C (CFTR, ABC_tran,ABC_membrane,TM=Y„ 473 422366, T83882, Hs 97927, ESTs, pkinase.none, 464
424905, NM.002497, Hs 153704, NIMA (never in mitosis gene a)-related k, pkιnase,TM=M„ 448 426925, NM.001196, Hs 315689, Homo εapienε cDNA FLJ22373 fis, clone H, Esterase,enolase,Peptιdase_S9,TM=M„ 445 439606, W79123, Hs 58561, G protein-coupled rxeptor 87, 7tm_1,TM=Y,SS=M, 440
400749, , , NM 003105* Homo sapiens sortilm-related, EGF,fn3,ldl_rxepLa,ldl_rxepLb,granulιn,BNR,TM=Y,SS=M, 438 425721 , AC002115, Hs 159309, uroplakin 1 A, transmembraπe4,TM=Y,SS=M, 433
444006, BE395085, Hs 10086, type I transmembrane protein Fn14, ldl_rxept_a,PKD,MHC_l,TM=M,SS=Y, 431 400751, , , NMJ03105* Homo sapiens sortilm-related, EGF,fn3,ldl_recept_a,ldl_recept_b,granulιπ,BNR,TM=Y,SS=M, 4 18 408908, BE296227, Hs 250822, seπne/threoniπe kinase 15, pkιnase,SS=M, 3 90 422152, AA909249, Hs 112282, solute earner family 30 (zinc transport, none.none, 388 458760, AI498631, Hs 111334, femtin, light polypeptide, cyεtatιn,ferrιtιn,hi8tone,HC03_cotranεp,SH3,RhoGAP,xan_ur_permeaεe,FCH,SS=M, 385
441218, BE327561, Hs 202345, ESTs, none,WD40,E1-E2 ATPase,Catιon_ATPase_C,Catιon_ATPase_N,Hydrolase, 378 419073, AW372170, Hε 183918, Homo εapienε cDNA FLJΪ2797 fis, clone NT, death,ZU5,SS=M, 376
451385, AA017656, , gb ze39h01 r1 Soares retina N2b4HR Homo , Atrophm-1,enoIase Atrophιn-1,Y_phosphatase,SH2,fibrιnogen_C,TIM, 360 412604, AW978324, Hs 1904, protein kmase C, iota, pkιnase,DAG_PE-bιπd,pkmase_C,OPR,TM=M„ 330 409582, R27430, Hs 271565, ESTs, none,Neur_chan_LBD,Neur_chan_memb, 328
441155, AW161008, Hs 7719, GABA(A) rxeptor-asεociated protein, MAP1_LC3,SS=M, 323 436740, AW975133, , gb EST387239 MAGE resequences, MAGN Homo, none,EPH_lbd,fπ3 pkmase.SAM, 320 418319, AW611703, Hs 190173, ESTs, Weakly similarto A46010 X-lmked , none.IRK, 320 409744, AW675258, Hs 56265, Homo εapienε mRNA, cDNA DKFZp586P2321 (f, none.NA.NA, 3 13 418764, N30531 , Hs 42215, protein phosphatase 1 , regulatory subuni, none.none, 3 10
400846, , , sortilm-related rxeptor, L(DLR class) , EGF,fn3,ldl_rxepLa,ldl_rxepLb,granulm,BNR,TM=Y,SS=M, 309 422005, BE266556, Hs 110702, Homo sapiens mRNA, cDNA DKFZp761 E212 (fr; none.Na.H.Exchanger; 303 426440, BE382756 Hs 169902, solute earner family 2 (facilitated glu, sugar_tπTM=Y,SS=M, 302 424187, AA336561, Hs 17287, ESTs, Weakly similar to S26689 hypotheti, IRK.none, 298 425852, AK001504, Hs 159651, death rxeptor 6, TNF superfamily member, death,TNFR_c6,TM=Y,SS=M, 293
401279, , , C13000351* gι|2494033|sp|Q64398|KDGD_MES, none.none, 288
406671, AA129547, Hs 285754, met proto-oncogeπe (hepatocyte growth fa Sema pkmase,TIG,PSI,none, 283
447081, Y13896, Hs 17287, potassium inwardly-rxufying channel, s, IRK,TM=Y„ 280
453619, H87648, Hs 33922, Homo sapienε, clone MGC 9084, mRNA, comp, pkmase,TM=M„ 275 441699, AW511126, Hs 127572, ESTs, none.Aa.trans, 273
458781, AI444821, Hs 63085, ESTs, Weakly similar to MPP3.HUMAN MAGUK, SH3,PDZ,Guanylate_kιn,L27,TM=M„ 273
446913, AA430650, Hs 16529, transmembrane 4 superfamily member (tetr, transmembrane4,TM=Y,SS=M, 270
453487, R31770, Hs 56562, ESTs, 7tm 1,none, 268
421279, AW664878, Hs 106645, ESTs, pkmaεe.πone, 268 419720, AA249131, Hs 337778, hypothetical protein FLJ11068, none.none, 265
452345, AA293279, Hs 29173, hypothetical protein FLJ20515, DSPc,TM=M„ 263
422247, U18244, Hs 113602, solute carrier family 1 (high affinity a, SDF,TM=Y„ 262
425212, AW962253, Hε 171618, ESTε, pkmaεe.none, 260
427344, NM 000869, Hs 2142, 5-hydroxytryptamιne (serotonin) receptor; Neur_chan_LBD,Neur chan_memb,TM=Y,SS=M, 258 423629, AW021173, Hε 18612, Homo sapiens cDNA FU21909 fis, clone H, voltage_CLC,CBS,noπe, 255
456737, BE247203, Hs 124831, CGI-67 protein, abhydrolase_2,TM=M,SS=M, 253
421585, U95626, Hs 302043, chemokine (C-C motif) receptor-like 2, 7tm_1,TM=Y,SS=M, 253
424028, AF055084, Hs 153692, Homo sapienε cDNA FLJ14354 fis, clone Y7, none.none, 250
448324, AI571356, Hs 34174, ESTs, Moderately similar to ALU8.HUMAN A, ICE_p20,CARD,ICE_p10,none, 250 402256, , , Target Exon, pkιnase,UBA,none, 243
452256, AK000933, Hs 28661, Homo sapiens cDNA FU10071 fis, clone HE, GDl,7tm_1,none, 240
419169, AW851980, Hs 262346, ESTs, Weakly similar to S72482 hypotheti, πoπe,spxtπn,SH3,PH,CH, 240
420634, S42457, Hε 1323, cyclic nucleotide gated channel alpha 1, cNMP_bιndιng,ιon_tranε,TM=Y„ 235
419630, W57756, , gb zd20g10 r1 Soareε.fetal heart_NbHH19W, zf-C3HC4,πone, 235 426227, U67058, Hs 154299, Human proteinase xtivated rxeptor-2 mR, 7tm_1,TM=Y,SS=M, 235
400704, , ; Target Exon, lιg_chan,SBP_bx_3,ANF_receptor,TM=Y,SS=M, 233
400149, , , Eos Control, xιd_phosphat,TM=Y,SS=M, 230
459327, AW149706, Hs 7859, gb xf41d02 x1 NCI_CGAP_Brn50 Homo sapieπ, PHD,PWWP,SET,pkιπase,ιg, 2 30
452220, BE158006, Hs 212296, ESTs, ιntegπn_A,FG-GAP,πoπe, 225 416690, H84078, Hs 108551, ESTs, pkinase.none, 223
408354, AI382803, Hs 159235, ESTs, none.none, 223
452203, X57522, , transporter 1, ATP-bindmg cassette, sub, ABCJran.ABC membrane,SRP54,Thymιdylate_kιn,TM=Y,SS=M, 221
405093, , , C12001101* gι|7522643|pιr||T32733 AMPA g, none.none, 220
412723, AA648459, Hε 335951 , hypothetical protein AF301222, none,TM=M„ 220 418738, AW388633, Hs 6682, solute earner family 7, (cationic ammo, none.none, 2 18
417185, NM.002484, Hs 81469, nucleotide binding protein 1 (E coli M , ParA,fer4_NιfH,ArsA_ATPase,TM=M„ 2 18
433222, AW514472, Hε 238415, diekkopf (Xenopuε laevis) homolog 4, noπe,PH04, 2 18
413627, BE182082, Hs 246973, ESTs, Armadιllo_seg,IBB,TM=M„ 2 18
407415, AF073328, , gb Homo sapienε tetrxyl e tranεporter-, none.none, 2 15 450592, AI701555, Hs 202562, ESTs, pkinase.none, 2 15
428767, AI421972, Hs 98802, ESTs, Moderately similar to T14342 NSD1 , none,pkιπase,ιg, 2 15
429012, AW629596, Hs 194726, BCL2-asεxιated athanogeπe 4, Sm,BAG,SS=M, 2 15
419122, AI401360, Hs 44410, ESTs, ABC_tran,ABC_membrane,none, 2 10
446420, AW015693, Hs 135614, ESTs, lon.traπs.none, 205 420076, AA827860, Hs 293717, ESTε, DUF59,pkιnaεe, 2 05
409416, AW388359, Hs 10667, ESTs, transmembrane4,TM=Y,SS=M, 203
428766, AA477989, Hs 98800, ESTs, TPR,7tm_1, 203
427001, NMJ06482, Hs 173135, dual-spxificity tyrosιne-(Y)-phosphoryl, pkιnase,TM=M„ 203 453709, AL119133, , protein kinase C substrate 80K-H, none.histone, 2 03 423341, AW242394, Hs 108660, ESTs, none.none, 2 00
456772, AW604297, Hs 129711, hepatitis A virus cellular receptor 1, ιg,TM=Y,SS=M, 1 88 427786, BE407863, Hs 256871 , ESTs, none,FG-GAP,7tm_1 , 1 65 423508, AW604297, Hε 129711, hepatitis A virus cellular rxeptor 1, ιg,TM=Y,SS=M, 1 00
447993, AW139525, Hs 170362, ESTs, none.none 1 00
TABLE 58B Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT Number Accession 414883 8371 2 AF274943 BG494894 AI719075 AA908783 AI935150 AI422691 AA910644 AA583187 BM272167 AI828996 AA527373 AW972459 AI831360 AA772418
AI033892 AA100926 AU154749 AI459432 AI423513 AI094597 AA740817 AI991988 AI090262 AI312104 BI256707 AA459522 AA416871 AI075239 AI339996 AA701623 Al 139549 AI336880 AA633648 AI989380 AI362835 AA399239 Al 146955 BF514270 N92892 AI348243 AI278887 AA459292 AI494230 BF507531 AI492600 AA962596 AW613002 AA293140 AA235549 BF108854 AA954344 N49682 AI457100 AW589407 AW300758 BE220715 BE220698 BE569091 BM009647 BF900351 AI537692 AI203723 AI857576 AA584410 AW371667 BM172363
438091 22448J AK054860 AV652198 AV652192 AV652138 AV652127 AV652194 BE935919 AV652017 AV651995 AV651548 AV646063 AV651985 AV646184 AV646179 AW880409 AA345002 BF155189 8E068931 X56197 AL603014 AW953629 BM263546 BE550772 AA701084 AI681352 AA358689 AW938841 BF438147 W05391 H75313 BF326185 AV646335 AV651589 AV646340AV651992AV646384AV646364AV687497 BF155183 AV646370 AW797876 AI906821 X56196 BE833835 AA628440 BE833808 BF224205 AA709126 BE673807 AI923886 AA947932 AI276125 AI185720 AW510698 AA987230 BE467708 AW898628 AW898544 AI146984 AW043642 AI288245 AI186932 AI635262 A1139455 AI298739 AI813854 AI024768 BE699445 BE699444 AI707807 D52654 AI214518 AI004723 AI698085 AW087420 AI565133 AA845571 AW898622 BF110144 AW513280 AI061126 BF362770 AI268939 AI435818 BF475318 AI024767 BE174213 AA757598 AA513019 AA902959 AI860794 AI334784 BF108411 BM310532 AW513771 AI951391 AI337671 BF095606 BF095601 BF095468 AW890091 BF095753 AW243400 AW898607 AW898616 BF362762 AI922204 AW898625 BE699468 BE174196 AW102923 D52715 BE699456 D52477 D55017 BF955933 BG623563 AV646254 AA463522 BI003244 AI299190 W40186 BE174210 BF939091 BF434180 AW579001 T55662 H01811 T52522 BF945037 BF955938 D54679 D53933 R67100 BG925552 BF999056 R83430 Z29922 T85791 W03942 H63289 AI091537 BF086583 AA345570 H48870 H80720T83523 BI039626 BI037700 R00353 BF155184 N98343 N79072 H01812 T55581
433470 6624 1 X75684 AL573167 AI445461 AI453743 AI983655 AI564644 AA977180 AI694111 AI591358 AW071625 AI678712 AI720939 AI927769 BE439796
AI963432 AA292956 AW192593 AI865838 AI696905 AI424384 AI161312 AI911921 AI597801 BI494959 AI240988 AI492554 AW262737 BE044033 AW008570AW629505 BI494958 AA088439 AA706057 BF222820 BF593608 BE501957AA524526 BE044134AW572531 AW015724 BE349186 AA043217 BE219784 AI799814 AA129575 AI671727 AI470033 BE646195 AW779725 AA903050 AA147228 AA404570 AI075878 W38161 AI972739 AW673152 AA723200 C06123 BF057147 AA627686 AA157944 AI990245 AA662517 T32487 AI800106 AI333170 A1859160 W45410 AI990827 AW275048 AA182640 AA478328 AI298935 AW085158 AW471421 AW103470 AW300456 AW191997 AI823466 AA962397 AA136658 AI251817 AW339104 AA724739 AA411100 AA191349 AA757735 AA037696 AI769516 AW772283 AA010631 AI692846 AI061065 H80983 R79933 AI950693 AI245632 AI349390 AA148284 AI798502 AA487893 AI621320 AW194272 C06365 AA953883 BE858936 AI918523 AI872628 AI927217 AI453453 AI189366 AW338678 AI261359 AI500576 BF477735 AI032569 AI972899 AI985583 Z28771 AI363829 AI693030 AA603586 BE773488 AW339301 BE773489 BE773462 BE773495 AI650338 BE773499 AI745717 BE811475 BE811470 BE811464 BE811418 BE811415 BE811400 BE811398 BE811388 BE811352 BE773501 BE773494 BE773486 BE773474 BE773473 BE773470 BE773461 BE811350 BE811337 BF593847 BG055071 AW675302 BF003068 AA719173 BE811348 AI582462 AI686240 BE773500 AI244845 AI565439 AI918453 AI472527 AI446740 AA035576 AA191414 AW674145 C05782 AI589264 D57558 AI468237 AI432033 AA989662 R21752 BF002457 AA988297 AL574095 AL576200 AL571074 AL574525 AL578810 BG498381 AI928364 BE879732 AA479834 AA479712 C17732 BM091258 BF843901 AW820230 C17476 BE327120 AA129574 AA136645 BF843900 AW806193 AA502832 AA649494 AL568520 AL547960 BE706937 BE811360 BE773498 BE811401 BE773484 BE811437 BE811380 BE811399 BF997171 BF757734 BE926037 AI377596 C06111 AW088968 BE811404 BE811472 AI865912 AI925607 AI871950 AI093510 BE905927 BE811435 AA191387 AW772000 BE811453 BE614379 BF844522 BI044896 AI744233 AW984527 C17504 BF843883 AI248307 BE773483 AI567995 W60075 BF941183 AI738844 BE811458 BE773481 AI262930 AA948565 BE706942 BE156360 T65026 AW242958 AW197954 BE905184 AA722206 AI344943 AI348877 AI334860 BE621857 BE156280 AA454099 AA037722 BF843897 AW806183 AA043216 BG482896 AA182734 AA877242 AW372926 H27252 R38114 BF851858 BE156214 AA190427 T91762 AA035067 AA837326 T10930 BF906587 BI755027 BG506731 BC008442 BC010166 AL550134 AL553096 AL548700 AL550751 AL547978 AL545286 AL540643 AU118627 AL601379 BI259821 BG741786 BI868522 AU135866 BI552770 BI259210 BI256520 BI255569 BG485098 BI258228 BG498501 BM044512 AU 133984 AL556586 BE745111 BI222633 AU133917 BG288151 BI260715 BI550550 BG500773 BI551761 BG707601 BI818593 BF691383 BG721129 BG541578 BE906666 BG751098 BI224135 BG400746 BG478065 BE790436 AW080238 AU137549 BG429896 BE392486 AW961686 BG721056 BE908365 BE546656 BG541235 AW583735 BG528290 BI260895 AW651691 BM048974 B 043805 BG142185 AA315188 AI446615 C06300 BG497644 AA088544 AI815987 BG528631 BE619182 AW239185 AW062910 AW062902 AA347236 F11933 AA488005 AA301631 AA376800 D56120 AA343532 AA308636 F00242 AA376086 AA316968 AA343799 BI870221 BE910282 BG538748 AW960564 AV732879 D16854 AA192519 BF922148 AA216013 BG624091 BE544387 BG507008 AW176446 BF790033 BE088925 BE088854 AA921353 R21800 AA011222 T97525
436729 6624 1 X75684 AL573167 AI445461 AI453743 AI983655 AI564644 AA977180 AI694111 AI591358 AW071625 AI678712 AI720939 AI927769 BE439796
AI963432 AA292956 AW192593 AI865838 AI696905 AI424384 AI161312 AI911921 AI597801 BI494959 AI240988 AI492554 AW262737 BE044033 AW008570 AW629505 BI494958 AA088439 AA706057 BF222820 BF593608 BE501957 AA524526 BE044134 AW572531 AW015724 BE349186 AA043217 BE219784 AI799814 AA129575 AI671727 AI470033 BE646195 AW779725 AA903050 AA147228 AA404570 AI075878 W38161 AI972739 AW673152 AA723200 C06123 BF057147 AA627686 AA157944 AI990245 AA662517 T32487 AI800106 AI333170 AI859160 W45410 AI990827 AW275048 AA182640 AA478328 AI298935 AW085158 AW471421 AW103470 AW300456 AW191997 AI823466 AA962397 AA136658 AI251817 AW339104 AA724739 AA411100 AA191349 AA757735 AA037696 AI769516 AW772283 AA010631 AI692846 AI061065 H80983 R79933 AI950693 AI245632 AI349390 AA148284 AI798502 AA487893 AI621320 AW194272 C06365 AA953883 BE858936 AI918523 AI872628 AI927217 AI453453 AH 89366 AW338678 AI261359 AI500576 BF477735 AI032569 AI972899 AI985583 Z28771 AI363829 AI693030 AA603586 BE773488 AW339301 BE773489 BE773462 BE773495 AI650338 BE773499 AI745717 BE811475 BE811470 BE811464 BE811418 BE811415 BE811400 BE811398 BE811388 BE811352 BE773501 BE773494 BE773486 BE773474 BE773473 BE773470 BE773461 BE811350 BE811337 BF593847 BG055071 AW675302 BF003068 AA719173 BE811348 AI582462 AI686240 BE773500 AI244845 AI565439 AI918453 AI472527 AI446740 AA035576 AA191414 AW674145 C05782 AI589264 D57558 AI468237 AI432033 AA989662 R21752 BF002457 AA988297 AL574095 AL576200 AL571074 AL574525 AL578810 BG498381 AI928364 BE879732 AA479834 AA479712 C17732 BM091258 BF843901 AW820230 C17476 BE327120 AA129574 AA136645 BF843900 AW806193AA502832 AA649494 AL568520 AL547960 BE706937 BE811360 BE773498 BE811401 BE773484 BE811437 BE811380 BE811399 BF997171 BF757734 BE926037 AI377596 C06111 AW088968 BE811404 BE811472 AI865912 AI925607 AI871950 AI093510 BE905927 BE811435 AA191387 AW772000 BE811453 BE614379 BF844522 BI044896 AI744233 AW984527 C17504 BF843883 AI248307 BE773483 AI567995 W60075 BF941183 AI738844 BE811458 BE773481 AI262930 AA948565 BE706942 BE156360 T65026 AW242958 AW197954 BE905184 AA722206 AI344943 AI348877 AI334860 BE621857 BE156280 AA454099 AA037722 BF843897 AW806183 AA043216 BG482896 AA182734 AA877242 AW372926 H27252 R38114 BF851858 BE156214 AA190427T91762 AA035067 AA837326 T10930 BF906587 BI755027 BG506731 BC008442 BC010166 AL550134 AL553096 AL548700 AL550751 AL547978 AL545286 AL540643 AU118627 AL601379 BI259821 BG741786 BI868522 AU135866 BI552770 BI259210 BI256520 BI255569 BG485098 BI258228 BG498501 BM044512 AU133984 AL556586 BE745111 BI222633 AU133917 BG288151 BI260715 BI550550 BG500773 BI551761 BG707601 BI818593 BF691383 BG721129 BG541578 BE906666 BG751098 BI224135 BG400746 BG478065 BE790436 AW080238 AU137549 BG429896 BE392486 AW961686 BG721056 BE908365 BE546656 BG541235 AW583735 BG528290 BI260895 AW651691 BM048974 BM043805 BG142185 AA315188 AI446615 C06300 BG497644 AA088544 AI815987 BG528631 BE619182 AW239185
AW062910 AW062902 AA347236 F11933 AA488005 AA301631 AA376800 D56120 AA343532 AA308636 F00242 AA376086 AA316968 AA343799
BI870221 BE910282 BG538748 AW960564 AV732879 D16854 AA192519 BF922148 AA216013 BG624091 BE544387 BG507008 AW176446
BF790033 BE088925 BE088854 AA921353 R21800 AA011222 T97525
437056 428504.3 AW976398 AI147061 AA765223 AA743380 AI803927 422940 58443.1 BC012771 BG397153 BF366196 AA337277 AA319285 AW843252 409745 MH1944.5 B1030997 AA921874AW188822 BI027862AI347618 AI361453 AI088754 A 207491 AA077391 BG012775 BG997382 AA286833 AA150722 BI007625
BI027864 BI009100 BI006275 BI006270 BI031000 BI029864 BI006277 BI007627 BI006266 BI006991 B1006990 BI007763 BI007762 BG997377
AA150780 BI033518 BI027818 BG015789 BI033807 AA341445
407347 810943.1 T23514 AI655785 418546 242836.1 T59708 AA224827 T59843 BE156903 432407 MH1429 12 BG036675 BF772005 BF771866 BG960386 BG960381 NM.005712 AF110315 BE074534 BE182776 BE158000 BE157999 BE714315 AW818104
AW847519 AA099426 AW817981 AW856396 BG961122 AA224498 AA308542 AW821833 BF902155 AI732411 BG778834 BG283641 BE748279
BE748870 BG319540 BE748864 BF739224 BG986155 AK057283 BI861466 AA663341 AA457591 BG949294 AW392886 AA071122 AA227849
AA584918 BG959570 BF773486 AL041698 BF959013 R87170 C16859 BF770411 BF771298 AI075321 L13823 AA216700 BF771864 AW861859
BE537068 C18935 AA155719 BF771172 BF769107 BF804964 AW818172 AW818143 AW392930AW817057 AW858044 BF746211 AA179928
AW861687 AW821826 BI055726 BF242643 AA207189 BF770412 BF771157 BG430030 AA055592
423387 2612.2 L13288 AA928785 AI608912 AW872978 AA565655 AI022915 AI304920 AI564366 AI668793 AI094557 T60038 R72302 H45409 AA508805 R46356
AA418798 BM129553 BM129126 BM129292 BM128865 AI808418 AI689932 AI806573 BF431808 AW872985 AW166269 H73241 T16182 AI264547
R73391 R72085 R72840 T83751 X75299 BF754348 R94105 AW449839 R73300 NM.004624 AI797007 BE045543 BF110021 BF754250 T83923
AW884084 AA903896 AA418962 L20295 R72351 H45098 AA961010 R73210 R46451 AW884085 BI022902 BI763932 BI910138
400211 3532.1 NM_003899 D63476 BM456434 AA778936 AA452871 AI052466 AW014138 AA448725 BE673088 AW028198 BI856378 BM150466 BM150674
BM148451 AW500880 AA180228 BE243507 BM144903 AA333656 AW503767 AA305470AW504819 AA978194 AW500776 BE872488AI032663
AA704686 AA652189 AA179463 AL535925 BE275744 BE277708 BE275715 AW504259 AA354483 BE244197 BE246232 D17055 AW013876
AW014877T09464 T08407 AA830246 AW897881 BE501192 BE501195AL044534 AA258853 BI037915AA448037 BM461769 BI825965 BE763352
AW167531 Z45588 AV721881 AA527273 AI573219 AA457036 AW439651 AW264418 AA577618 AI802954 AA902292 AA468752 AI380374 AA722690
AI867708 AA916982 AI291576 AW190427 AI338089 AI653744 AI306665 AW513541 AW440077 AI370014 AA904269 AW188378 AI671644 AW193386
AI261832 AA775336 BF436811 AI582703 AI278635 BE440186 AA617898 AA648948 BI491837 BF590311 AA448633 F27048 F37022 AW770819
AA258808 AI369564 AW503675 AA777194 BE501048 BF222087 AA042973 AI868087 AA911460 Z41274 AI919082 T16746 AA447634 AI282427
F22456 T15901 AA825298 AW007436 BE934303 BG981939 AW373814 BM151638 AW956921 BM150080 BM153173 BM147451 BF953992 AA916696
AW444935 M78398 AW581147 AW608258 AA651910 AA132152 AW806295 T30326 D20054 AA310837 T06543 BM194508 BM193225 BM469348
AW964920 AA325930 BI833627 AW952193 AA738189 AA321051 BG987199 BF953967 T08890 BE869543 BG742857 BG988685 AA456880
BG001842 BF809452 AW892083 BF944342 T49551 W69981 BF764519 T15869 AA132030
400158 2166.1 BC000486 BC001930 U15008 NM.004597 BG326561 AV761269 BF212132 BG113313 BI838038 BG944198 BG255198 BG164334 BM013507
AV682717 BF028761 BG755489 BG030141 BG105499 BE440103 BF727449 BM454228 BG912181 BM015197 BG395995 Al 126579 AW248204
BI857394 BI857319 BG944205 BG323958 BI092930 AV756576 AA280959 BF033078 BE539360 AW247174 BG107836 BE796975 BG170920 AI148142
AI092009 AI336349 AV713409 BF685591 BE616029 AV713166 BE909458 BE743868 BM018218 AI340153 BE792567 BE206806 AI159916 AI184271
BE208585 BI862286 G18760 BG219364 AI122677 BE207297 BF754798 AA314384 BE873951 BG207294 AI148198AI336189 A1141094 A1308985
BF220098 AI143289 BE856397 AA644001 BE675402 AJ346708 AI052809 AI140082 BF081542 AI342428 AI479625 AA278456 AI750163 BE707501
BG944510 AA314616 AA315774 BF360721 BE738404AA814194 AA477195AA932107 F36858 AA363159 BE865458 AA354147AW904224AI055855
AA380365 F28474 D59140 AA341946 AA993339 AA323350 F24344 AA374436 BG942061 AA636015 AA852919 T31486 F36334 BG943190 T30319
BG943153 BG941836 T32569 T31160 AA311749 BE710086 BE709911 W23826 BG941639 BF769034 AA026407 AA229555 AV756340AV714380
453826 366136.1 AL138129 BG003205 AL138179 BI021773 BE064231 447727 10123.14 AL520734 BI666852 BF870571 BF945361 BF945354 AI770086 BI861138 AI421079 AL043200 BG683612 AW946265 400121 3532.1 NM 003899 D63476 BM456434AA778936 AA452871 AI052466AW014138AA448725 BE673088 AW028198 BI856378 BM150466 BM150674
BM148451 AW500880 AA180228 BE243507 BM144903 AA333656 AW503767 AA305470 AW504819 AA978194 AW500776 BE872488 AI032663
AA704686 AA652189 AA179463 AL535925 BE275744 BE277708 BE275715 AW504259 AA354483 BE244197 BE246232 D17055 AW013876
AW014877 T09464 T08407 AA830246 AW897881 BE501192 BE501195 AL044534 AA258853 BI037915 AA448037 BM461769 BI825965 BE763352
AW167531 Z45588 AV721881 AA527273 AI573219 AA457036 AW439651 AW264418 AA577618 AI802954 AA902292 AA468752 AI380374 AA722690
AI867708 AA916982 AI291576 AW190427 AI338089 AI653744 AI306665 AW513541 AW440077 AI370014 AA904269 AW188378 AI671644 AW193386
AI261832 AA775336 BF436811 AI582703 AI278635 BE440186 AA617898 AA648948 BI491837 BF590311 AA448633 F27048 F37022 AW770819
AA258808 AI369564 AW503675 AA777194 BE501048 BF222087 AA042973 AI868087 AA911460 Z41274 AI919082 T16746 AA447634 AI282427
F22456 T15901 AA825298 AW007436 BE934303 BG981939 AW373814 BM151638 AW956921 BM150080 BM153173 BM147451 BF953992 AA916696
AW444935 M78398 AW581147AW608258AA651910AA132152 AW806295 T30326 D20054 AA310837T06543 BM194508 BM193225 BM469348
AW964920 AA325930 BI833627 AW952193 AA738189 AA321051 BG987199 BF953967 T08890 BE869543 BG742857 BG988685 AA456880
BG001842 BF809452 AW892083 BF944342 T49551 W69981 BF764519 T15869 AA132030
415327 9792.2 BM048470 BG983877 N92089 Z43545 F05783 R35182 H22769 H71928 H63921 R94394AW195830 AA630220 F02030 R60760 R08204 H71929
BE464731 R62568 H63520 H77840 AL515501 F01971 T71768 N55275 AA883505 AW606824 AA704682 N74193 W57593 AW753776 H60439
AI076352 R31485 BE160931 AW130730 BE160869 AW580256 AW902073 BE702158 AW382079 N76884 BF431013 H38156 AV648937 H80573
455358 11600351 AW902569 AW902557 AW902654 AW902641 AW902650 AW902741 AW902644 415204 18655081 Z25288 R85077 F00323 D82802 T27434 425854 2638_3 BF184345 AA364846 BI494468 AA775693 BF195801 AA749190 AI480223 BE327332 AI470017 AW628345 AI917472 AI972264 AI375571 AI652583
AI656167 AI983110 BE550378 AW015085 BE552318 AI631475 AI433447 AA534540 AI865480 AI468119 BF110875 AW512059 W58721 AA827482
R59357
424160 5320_3 AW370493 AA923304 AI660828 AA502611 BI017370 AA039704 W65393 BE938514 W65295 BF919626 BI759440 BI838879 AA336207 F12441
8F171187 BE185031 T74062 A 904410 AA280078 BF919629
417086 1154_2 AK056605 AK056969 AW380724AA195950 F21243 Z17422AA176595 AA176955 AA194350 BC005933 BC017866 AA196396 Z24810AA181361
AA193115 AA086465 F25194 F30130 AA180013 AJ346143 F20589 F20620 F29371 F32439 F25153 F32146 F26110 F28506 F25307 F27533 F20375
F32370 AA653078 BF574897 Z24852 F00172 T30560 AW449825 AI620346 BG986374 BE706521 C02691 AL596834 F31902 F26078 AA670099
BF475555 F30818 F37524 AJ346558 F28050 F17933 F31637 C03413 AI092152 AA180743 AA085730 F21998 F20854 F18944 F31180 F37937 F37738
AA193162 Z17344AA192546
411188 1072487.1 AW821260 BE162466 BE161168
417529 3302462 -1 AA203634
417527 2431831 1 AA203524 W88451
451385 850221 AA019761 AA017656 AA017374
436740 12390081 AW975133 AA805813 AA729943
419630 373105 BF223647 AA204668 AA256086 BF574707 W57756 AA249070 BI906494 AA248011
400149 164581 BC003160 NM.001610 X12548 BG386685 BI760866 BI559619 BG323829 AU135543 BI834101 AU142120 AU124511 AU124889 AL558171 AU117286
BI824000 BG386610 BI753285 BI223475 AU134828 BM126369 BE206493 BF751498 AL544274 AY007137 BI828921 BE870130 BF771242 BI835451
BI765655 BI820955 B1223344 BG015924 BI759894 AL527413 BF310588 N31870 N23974 BE514914T48863 AW860257 BF334625 AA883860
AU144168 AA442562 AU159491 AU148353 AA564123 AU 148667 AI377256 AW664004 AI871712 AI141486 AI332351 AI339094 BE206109 AW519033
AI817729 AI332490 AI149455 AI857411 AI763154 AI751608 AI377222 AI081956 AW664229 AI275872 AW168546 AA975270 AI367408 AI687729
AI269164 AW105344 BM193081 BE550930 A1082116 AA854691 AΪ056249 AI221062 AI290113 D51818 AA732409 BG055125 N85878 AU156121 BF093671 AA053070 T28548 AL570460 BI006862 BI007207 AA373620 W95069 AA629136 AA708164 AI014886 AW168697 D51623 AA577168 AI094208 AA028946 AA975078 R16815 BG151132 AI276297 D51676
452203 2630.1 BC014081 NM.000593 X57522 L21208 L21207 L21206 L21205 L21204 AL561404 AL546423 AL560492 AL556882 AL541576 AL550654 BI823519
BI770023 AL554969 BI489906 AI304693 AW295947 BM146642 X57521 BG820143 BE898390 F06770 F12630 BM423610 AL561518 BM009470 BG742981 AA279685 AA847441 AA313737 BF172639 BF897216 BF914190 BF903647 S70277 AI569694 AW073296 AI361433 AA564644 AA487429 BE858232 AA838610 AI539114 AI719375 AI829129 BG057675 AI423422 AU158860 BE300655 AW170777 AA586956 AL571889 AL556850 AL576404 AL582800 BI256544 BF342301 BG875994 AA054458 AA353161 AI940434 BE816522 AL577636 AI479650 AW150377 AU154395 AW951271 AI032220 AI819778 A1346733 AW771150 AW512525 AI249904 AA279809 AI352549 AW512517 BG056280 AA521222 BE271141 AL581932 AL541575 BI819184 AV660190 AL556475 AI620020 AW089888 AW079179 Z21518 AA687601 F04651 AI783961 T57198 AI433367 T78652 AL554968 AA365648 AL582619 BE874601 BF804669 AL574458 BM145502 AI266514 A1538823 AI475626 AA948210 AA884054 AA487637 AA031844 AA535221 AW794256 AW361447 BE788505 AI682892 AA830989 AA862356 AA653084 BM009154 AA135727 H05927 H23433 R42244 N79997 AW366665 AW366601 AA678742 AL556474 AA135770 BE774050 BF914200 H88457 AA627746 BI560216 BI753586
453709 59915 1 AK057669 AK054977 AL519747 BE893744 BM313248 BG913430 H80793 BF813504 N36311 N39276 H95973 BF791919 BE739392 BE144239
AA074615 AI291059 AI681053 AA702355 BF439899 AW055166 AI096957 BF223853 AL119659 AI692209 BM312961 AI869297 BE466252 AI292024 AA402764 AI214620 AA765312 BF380770 AA442682 AL519746 AW295039 AI037878 AW473433 AI499437 AI401618 AI130831 AA427406 AI042138 BG272488 AI828769 AI828764 AI189390 W84635 AA398496 AA761672 AA699520 AI200406 N68093 AI143913 AA993133 AA613306 AI050971 AA661905 AA722687 AI749977 AA829345 BG057324 BF001339 AA910169 AA765133 AI360722 AI701849 AI365083 H95974 AI830377 AI312866 AI370491 BE858907 N62185 AA705746 BE379632 W93803 AI440333 AW367670 AW367640 N77131 BF993216 AI858263 W52329 N68106 R83113 R85153 BE380058 AA082537 AA729731 W23495 W31190 BF995236 BF968827 BF355168 N24508 AA215711 BF170735 AA280395 BE738851 AW367707 AA630879 AA428420 R76236 BG567847 N25931 AA173568 AI073567 AA004957 AI539585 N95093 H99798 H95072 H96853 AA215712 AA034214 R85096 H82051 H80794 R44954 AA278972 H68352 H68346 R94750 R89010 R67951 H65817 N24891 AA173731 AI693577 BE181027 AA709461 BE181002 W60239 BF987598 BF995279 H17483 R76237 AL119133 BF964815 AW663315 H65903 H17591 R20167 AA310039 R58734 R58506
TABLE 58C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in thiε column are Genbank Identifier (Gl) numberε "Dunham I et al " referε to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495 Strand Indicates DNA εtrand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400843 9188605 Plus 58635970,76537784,8892-9023,9673-9807
404942 7382153 Plus 92095-92252
400752 7331445 Minuε 36215-36461
400496 9743564 Pluε 41515-41695
404568 9966995 Minuε 92893-93116
403912 7710730 Minuε 72000-7229072431-72700,72929-73199
402328 4464283 Minuε 13758-13922,14558-14752
404891 7329392 Plus 84974-85125
405036 7543748 Minus 121957-122129
400845 9188605 Plus 34428 34612
403212 7630897 Minus 156037-156210
401927 3873185 Minus 112000-112137
Table 59A lists about 1170 genes up regulated in prostate cancer compared to normal adult tissues These were selxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" prostate cancer to "average" normal adult tisεueε waε greater than or equal to 82 The "average" proεtate cancer level was set to the 75* percentile amongst prostate cancers The "average" normal adult tisεue level was set to the 50* percentile amongst non-malignant bssueε In order to remove gene spxific bxkground levels of non-spxific hybridization, the 10* percentile value amongst the non-malignant tisεues was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 59A ABOUT 1170 GENES UP-REGULATED IN PROSTATE CANCER COMPARED TO NORMAL ADULT TISSUES
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Acceεεion number, Genbank xceεεion number UnigenelD Unigene number Unigene Title Unigene gene title R1 Ratio of prostate tumor to normal adult body tisεue
Pkey ExAccn Unigene ID Unigene Title R1
428330 L22524 Hs 2256 matnx metalloproteinase 7 (matπlysiπ, 108 1
426747 AA535210 Hs 171995 kallikrein 3, (prostate spxific antigen 1025
420923 AF097021 Hs 273321 differentially expreεεed in hematopoieti 905
416854 H40164 Hs 80296 Purk je cell protein 4 798
425075 AA506324 Hs 1852 acid phoεphatase, prostate 71 6
431103 M57399 Hs 44 pleioirophin (hepaπn binding growth fac 706
434666 AF151103 Hs 112259 T cell rxeptor gamma Ixus 691
419551 AW582256 Hs 91011 anteπor gradient 2 (Xenepus laevis) hom 664
413859 AW992356 Hs 8364 Homo sapiens pyruvate dehydrogenase kina 664
420154 AI093155 Hs 95420 JM27 protein 639
428336 AA503115 Hs 183752 microseminoprotem, beta- 61 4
400287 S39329 Hs 181350 kallikrem 2, prostatic 597
416602 NM 006159 Hε 79389 πel (chicken) like 2 546
428398 AI249368 Hs 98558 ESTs 546
432441 AW292425 Hs 163484 ESTε 546
414569 AF109298 Hs 118258 prostate cancer assxiated protein 1 542
417771 AA804698 Hs 82547 retinoic xid receptor responder (tazaro 542
448999 AF179274 Hs 22791 transmembrane protein with EGF-like and 537 437145 AF007216 Hs 5462 solute carrier family 4, sodium bicarbon 496
446057 AI420227 Hs 149358 ESTs, Weakly similar to A46010 X linked 480
431579 AW971082 Hε 222886 ESTs Weakly similar to TRHY.HUMAN TRICH 46 8
400299 X07730 Hs 171995 kallikrein 3, (prostate spxific antigen 45 0
427674 NM 003528 Hs 2178 H2B histone family, member Q 449
432374 W68815 Hs 301885 Homo sapienε cDNA FLJ11346 fis, clone PL 445
422487 AJ010901 Hs 198267 mucin 4 trxheobranchial 445
415314 N88802 Hs 5422 glycoprotein M6B 43 2
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (plxenta 41 9
409262 AK000631 Hs 52256 hypothetical protein FLJ20624 41 1
423582 BE000831 Hs 23837 Homo sapienε cDNA FLJ11812 fis, clone HE 405
400298 AA032279 Hs 61635 εix tranεmembrane epithelial antigen of 395
439176 AI446444 Hs 190394 ESTε, Weakly similarto B28096 line 1 pr 393
416585 X54162 Hs 79386 leiomodm 1 (smooth muscle) 390
447726 AL137638 Hs 19368 matπlin 2 386
426174 AA547959 Hs 115838 ESTε 38 1
425071 NM 013989 Hs 154424 deiodmase, lodothyronme, type II 38 0
417067 AJ001417 Hs 81086 solute earner family 22 (extraπeuronal 37 5
414217 AI309298 Hs 279898 Homo sapiens cDNA FLJ23165 fis clone L 370
433043 W57554 Hs 125019 lymphoid nuclear protein (LAF-4) mRNA 355
400302 N48056 Hs 1915 folate hydrolase (prostate-spxific memb 35 1
453096 AW294631 Hs 11325 ESTε 351
419239 AA468183 Hs 184598 Homo εapienε cDNA FLJ23241 fiε, clone C 349
427665 AF134803 Hs 180141 cofilin 2 (muscle) 349
415539 AI733881 Hs 72472 BMP-R1B 349
428411 AW291464 Hs 10338 ESTs 346
428819 AL135623 Hε 193914 KIAA0575 gene product 343
401424 NM 001172 Homo sapiens arginaεe type II 340
452114 N22687 Hε 8236 ESTs 340
426990 AL044315 Hε 173094 Homo sapienε mRNA for KIAA1750 protein 33 8
448045 AJ297436 Hs 20166 proεtate stem cell antigen 331
421552 AF026692 Hs 105700 sxreted frizzled related protein 4 329
432101 AI918950 Hs 123642 EphA3 327
427398 AW390020 Hs 20415 chromosome 21 open reading frame 11 324
426716 NM 006379 Hs 171921 sema domain, immunoglobulin domain (Ig), 324
434025 AF114264 Hs 216381 Homo sapienε clone HH409 unknown mRNA 324
414591 AI888490 Hs 55902 ESTε, Weakly similar to ALU8.HUMAN ALU S 323
453355 AW295374 Hs 31412 Homo sapiens cDNA FLJ 11422 fis, clone HE 31 9
408380 AF123050 Hs 44532 diubiquitin 31 6
429500 X78565 Hs 289114 hexabrxhion (tenascm C, cytotactin) 31 4
453370 AI470523 Hs 139336 ATP binding casεette, sub-family C (CFTR 31 3
408369 R38438 Hs 182575 solute earner family 15 (H"??"? transport 31 2
408001 AA046458 Hs 95296 ESTs 308
440274 R24595 Hs 7122 εcrapie reεponsive protein 1 307
417332 AW972717 Hε 288462 hypothetical protein FLJ21511 303
442993 BE018682 Hε 166196 ATPase, Clasε I, type 8B, member 1 302
433404 T32982 Hε 102720 ESTs 296
459247 N46243 Hε 110373 ESTs, Highly similar to T42626 sxreted 296
418829 AA516531 Hs 55999 NK homeobox (Drosophila), family 3, A 29 3
459290 NM 001546 Hs 34853 inhibitor of DNA binding 4, dominant neg 29 2
418827 BE327311 Hs 47166 HT021 29 0
410330 AW023630 Hs 46786 ESTs 28 6
450377 AB033091 Hs 74313 KIAA1265 protein 286
424012 AW368377 Hs 137569 tumor protein 63 kDa with εtrong homolog 285
441633 AW958544 Hs 112242 normal mucoεa of eεophagus spxific 1 28 2
429290 AF203032 Hs 198760 neurofilament, heavy polypeptide (200kD) 277
452340 NM 002202 Hs 505 ISL1 transcnption fxtor, LIM/hom∞doma 277
421566 NM.000399 Hε 1395 eariy growth responεe 2 (Krox-20 (Droεop 276
409361 NM 005982 Hs 54416 εine xuliε homeobox (Drosophila) homolo 274
446100 AW967109 Hs 13804 hypothetical protein dJ4620232 274
407202 N58172 Hs 109370 ESTs 274
434078 AW880709 Hs 283683 chromosome 8 open reading frame 4 274
442870 N45018 Hs 8769 hypothetical protein DKFZp761J17121 273
403047 NM 005656* Homo sapienε transmembrane pr 272
407709 AA456135 Hs 23023 ESTs 27 0
433444 AW975324 Hs 129816 ESTs 26 8
415989 AI267700 Hs 317584 ESTs 268
430539 AK001489 Hs 242894 ADP-πbosylation factor-like 1 265
408221 AA912183 Hs 47447 ESTε 26 5
448519 AW175665 Hs 278695 Homo εapienε prostem mRNA, complete eds 264
437179 AA393508 Hs 300642 εerologically defined colon cancer antig 264
426457 AW894667 Hs 169965 chimeπn (chimaeπn) 1 262
444484 AK002126 Hs 11260 hypothetical protein FLJ 11264 26 2
400292 AA250737 Hs 72472 BMP-R1B 260
433647 AA603367 Hs 222294 ESTε 26 0
429220 AW207206 Hs 136319 ESTs 258
427871 AW992405 Hs 59622 Homo sapiens, clone IMAGE 3507281, mRNA, 256
448106 AI800470 Hs 171941 ESTs 255
415992 C05837 Hs 145807 hypothetical protein FLJ 13593 255
452792 AB037765 Hs 30652 KIAA1344 protein 25 3
407910 AA650274 41296 fibronxtin leucine πch transmembrane p 25 2
428862 NM 000346 Hε 2316 SRY (sex determining region Y) box 9 (ca 249
418961 AW967646 Hs 23023 ESTs 248 451027 AW519204 Hs 40808 ESTε 24 5
413517 N76712 Hs 44829 ESTs, Weakly similar to I38022 hypotheti 245
409731 AA125985 Hs 56145 thymosm, beta, identified in neuroblast 244
418396 AI765805 Hs 26691 ESTs 24 1
412088 AI689496 Hs 108932 ESTs 24 1
429573 AA884407 Hs 211595 protein tyrosine phosphatase, non recept 240
411644 H92064 Hs 278626 Arg/Abl interacting protein ArgBP2 240
409619 AK001015 Hs 55220 BCL2-assxιated athaπogene 2 239
433466 AA508353 Hs 105314 relaxm 1 (H1) 237
431657 AI345227 Hs 105448 ESTs, Weakly similar to B34087 hypotheti 236
440995 T57773 Hs 10263 ESTε 235
432278 AL137506 Hs 274256 hypothetical protein FLJ23563 23 2
428695 AI355647 Hs 189999 purmergic rxeptor (family A group 5) 231
424720 M89907 Hs 152292 SWI/SNF related, matrix assxiated, xti 229
440260 AI972867 Hs 7130 copine IV 225
443622 AI911527 Hs 11805 ESTs 222
426418 M90464 Hs 169825 collagen, type IV, alpha 5 (Alportεyπdr 220
425383 D83407 Hs 156007 Down syndrome cπtical region gene 1-lιk 21 9
450642 R39773 Hs 7130 copine IV 21 9
417421 AL138201 Hs 82120 nuclear rxeptor subfamily 4, group A, m 21 8
435981 H74319 Hs 188620 ESTs 21 8
450693 AW450461 Hs 203965 ESTs 21 7
444784 D12485 Hs 11951 xtonudeotide pyrophosphatase/phosphodi 21 7
423242 AL039402 Hs 125783 DEME-6 protein 21 7
408621 AI970672 Hs 46638 chromosome 11 open reading frame 8 21 6
408000 L11690 Hs 620 bullous pemphigoid antigen 1 (230/240kD) 21 5
404210 NM.005936 Homo sapienε myeloid/lymphoid 21 5
417622 AW298163 Hs 82318 WAS protein family, member 3 21 5
419526 AI821895 Hs 193481 ESTs 21 5
442799 AI564739 Hs 68505 ESTs 21 4
424846 AU077324 Hs 1832 neuropeptide Y 21 3
420195 N44348 Hs 26243 Homo εapiens cDNA FLJ11177 fis, clone PL 21 3
429922 Z97630 Hs 226117 H1 histone family, member 0 21 3
422511 AU076442 Hs 117938 collagen, type XVII, alpha 1 21 3
437330 AL353944 Hs 50115 Homo sapiens mRNA, cDNA DKFZp761 J1112 (f 21 2
431474 AL133990 Hs 190642 ESTs 21 2
430887 N66801 Hs 260287 KIAA1841 protein 21 1
416655 AW968613 Hs 79428 BCL2/adenovιrus E1B 19kD-ιnteractmg pro 21 1
408912 AB011084 Hs 48924 KIAA0512 gene product, ALEX2 21 1
445133 AW157646 Hs 153506 ESTε 21 0
421513 X00949 Hs 105314 relax 1 (H1) 21 0
413746 AA133243 Hs 171553 ESTε, Moderately similar to CLC3.HUMAN C 208
446795 AI797713 Hs 156471 ESTs 207
440774 AI420611 Hs 127832 ESTs 207
407168 R45175 Hs 117183 ESTs 206
417511 AL049176 Hs 82223 chordin-like 206
431130 NM 006103 Hs 2719 epididymis-spxific, whey-xidic protein 20 6
451277 AK001123 Hs 26176 hypothetical protein FLJ10261 206
411800 N39342 Hs 103042 microtubule-assxiated protein 1B 205
446469 BE094848 Hs 15113 homogentisate 1,2-dιoxygenase (homogenti 205
427138 N77624 Hs 173717 phosphatidic xid phosphatase type 2B 205
409758 AW474960 Hs 182258 ESTs, Weakly similar to I78885 seπne/th 205
424897 D63216 Hs 153684 fnzzled-related protein 205
430280 AA361258 Hs 237868 interleukin 7 rxeptor 204
401197 ENSP00000229263* HSPC213 203
452814 AI092790 Hs 334703 hypothetical protein FLJ14529 203
429918 AW873986 Hs 119383 ESTs 202
423073 BE252922 Hs 123119 MAD (mothers against dxapentaplegic, Dr 202
453469 AB014533 Hs 33010 KIAA0633 protein 202
444922 AI921750 Hs 144871 Homo sapiens cDNA FLJ13752 fis, clone PL 200
436396 AI683487 Hs 152213 wmgleεs-type MMTV integration εite fami 200
419440 AB020689 Hs 90419 KIAA0882 protein 200
429170 NM.001394 Hs 2359 dual εpxificity phosphatase 4 199
441690 R81733 Hs 33106 ESTs 199
423690 AA329648 Hs 23804 ESTs, Weakly similar to PN0099 son3 prot 198
423044 AA320829 Hs 97266 protxadheπn 18 198
410929 H47233 Hs 30643 ESTs 19 7
427019 AA001732 Hs 173233 hypothetical protein FLJ 10970 197
431556 AF016028 Hs 183428 sarcoεpan (Kraε oncogene aεεxiated gene 196
409632 W74001 Hs 55279 εeππe (or cyεteine) proteinaεe inhibito 196
444190 AI878918 Hs 10526 cyεteine and glyciπe-πch protein 2 196
407118 AA156790 Hs 262036 ESTε, Weakly similar to Z223.HUMAN ZINC 195
416370 N90470 Hs 203697 ESTs, Weakly similar to I38022 hypotheti 194
431217 NM 013427 Hs 250830 Rho GTPase xtivatmg protein 6 194
430187 AI799909 Hs 158989 ESTε 19 3
420120 AL049610 Hs 95243 transcription elongation factor A (Sll)- 193
434423 NM 006769 Hs 3844 LIM domain only 4 192
417381 AF164142 Hs 82042 solute earner family 23 (nucleobase tra 19 1
409062 AL157488 Hs 50150 Homo εapiens mRNA, cDNA DKFZp564B182 (fr 190
409038 T97490 Hs 50002 small inducible cytokine subfamily A (Cy 18 9
436032 AA150797 Hs 109276 latexin protein 189
431548 AI834273 Hs 9711 novel protein 189
418565 AK001529 Hs 86149 phosphoinositol 3 phosphate binding prot 189 445929 AI089660 Hs 323401 dpy 30 like protein 188
453160 AI263307 Hs 239884 H2B histone family, member L 188
439897 NM 015310 Hs 6763 KIAA0942 protein 188
453874 AW591783 Hs 36131 collagen type XIV, alpha 1 (uπdulm) 188
434987 AW975114 Hs 293273 ESTs 187
407690 R47799 Hs 266957 hypothetical protein FLJ14281 187
421913 AI934365 Hs 109439 osteoglycin (osteoinductive factor, mime 187
418819 AA228776 Hs 191721 ESTs 18 7
450831 R37974 Hs 25255 ESTs 187
415691 AW963979 Hs 24723 ESTs 187
417124 BE122762 Hs 25338 ESTs 18 7
445162 AB011131 Hs 12376 piccolo (presynaptic cyto atπx protein) 186
426647 AA243464 Hs 294101 pre B-cell leukemia transcription fxtor 185
410099 AA081630 Hs 169387 KIAA0036 gene product 18 5
430722 AW968543 Hs 203270 ESTs, Weakly similar to ALU1.HUMAN ALU S 18 5
420344 BE463721 Hs 97101 putative G protein-coupled rxeptor 18 5
436420 AA443966 Hs 31595 ESTs 184
427315 AA179949 Hs 175563 Homo sapienε mRNA, cDNA DKFZp564N0763 (f 184
418432 M14156 Hs 85112 insulin like growth factor 1 (somatomedi 183
410765 AI694972 Hs 66180 nucleosome assembly protein 1-lιke 2 183
444931 AV652066 Hs 75113 general transcription factor IIIA 182
437446 AA788946 Hs 16869 ESTs Moderately similar to CA1 C RAT COL 182
439569 AW602166 Hs 222399 CEGP1 protein 18 1
417061 AI675944 Hs 188691 Homo sapiens cDNA FLJ12033 fis, clone HE 18 1
424682 AW604804 Hs 151717 KIAA0437 protein 180
432435 BE218886 Hs 282070 ESTs 179
443547 AW271273 Hs 23767 hypothetical protein FLJ 12666 178
431121 AW971157 gb EST383245 MAGE resequeπceε, MAGL Homo 178
410467 AF102546 Hs 63931 dxhshund (Drosophila) homolog 177
407110 AA018042 Hs 252085 Prader-Willi/Angelman syndrome-5 177
440703 AL137663 Hs 7378 Homo sapienε mRNA, cDNA DKFZp434G227 (fr 177
429925 NM 000786 Hs 226213 cytxhrome P450, 51 (laπoεterol 14-alpfιa 176
427958 AA418000 Hs 98280 potassium intermediate/small conductance 176
421059 AI654133 Hs 30212 thyroid rxeptor interxting protein 15 175
430487 D87742 Hs 241552 KIAA0268 protein 174
419355 AA428520 Hs 90061 progesterone binding protein 174
417412 X16896 Hs 82112 interleukin 1 receptor, type I 173
423943 AF163570 Hs 135756 polymerase (DNA directed) kappa 173
434217 AW014795 Hs 23349 ESTs 173
439444 AI277652 Hs 54578 ESTs, Weakly similar to I38022 hypotheti 172
447809 AW207605 Hs 164230 ESTs, Highly similar to JC72663',5'-oyc 17 2
430177 AW969233 Hs 302746 MSTP028 protein 172
432473 AI202703 Hs 152414 ESTs 171
421823 N40850 Hs 28625 ESTs 171
418522 AA605038 Hs 7149 Homo sapiens cDNA FLJ21950 fis, clone H 170
420092 AA814043 Hs 88045 ESTε 170
414602 AW630088 Hs 76550 Homo sapiens mRNA, cDNA DKFZp564B1264 (f 170
417426 NM 002291 Hs 82124 laminin, beta 1 170
400297 AI127076 Hs 334473 hypothetical protein DKFZp56401278 170
401747 Homo sapienε keratin 17 (KRT17) 170
424181 AL039482 Hs 142517 Homo εapieπε mRNA, cDNA DKFZp434P0810 (f 170
442369 AI565071 Hs 159983 ESTε 16 9
432966 AA650114 Hs 325198 ESTs 16 9
426657 NM 015865 Hs 171731 solute earner family 14 (urea transport 16 8
419536 AA603305 gb np12d11 s1 NCI_CGAP_Pr3 Homo sapienε 16 8
443745 AB039670 Hs 9728 ALEX1 protein 16 8
438899 AF085833 Hs 135624 ESTε 16 8
418555 AI417215 Hs 87159 hypothetical protem FLJ12577 168
442064 AI422867 Hs 88594 ESTε 16 8
409385 AA071267 gb zm61g01 r1 Stratagene fibroblast (937 16 5
453070 AK001465 Hs 31575 SEC63, endoplasmic reticulum traπslxon 16 4
443801 AW206942 Hs 253594 ESTs 163
437536 X91221 Hs 144465 ESTs 163
409196 NM 001874 Hs 334873 carboxypepudase M 163
438337 AK002058 Hs 6166 hypothetical protein FLJ11196 163
416239 AL038450 Hε 48948 ESTs 163
448290 AK002107 Hs 20843 Homo sapienε cDNA FLJ 11245 fiε, clone PL 162
407192 AA609200 gb aF12e02 ε1 Soares.testiε.NHT Homo εap 162
409060 AI815867 Hs 50130 nxdin (mouεe) homolog 16 1
442571 C06338 Hε 165464 ESTε 161
419713 AW968058 Hε 92381 nudix (nucleoside diphosphate linked moi 16 1
426125 X87241 Hε 166994 FAT tumor suppressor (Drosophila) homolo 160
450164 AI239923 Hε 30098 ESTs 160
429663 M68874 Hε 211587 phospholipase A2, group IVA (cytosolic 160
408990 AL022395 Hs 49526 f-box and leucine πch repeat protein 4 160
417094 NM.006895 Hs 81182 histamme N-methyltransferaεe 160
436024 AI800041 Hε 190555 ESTε 160
412652 AI801777 Hε 6774 ESTε 160
456516 BE172704 Hs 222746 KIAA1610 protein 160
452576 AB023177 Hs 29900 KIAA0960 protein 15 9
430299 W28673 Hε 106747 senne carboxypeptidase 1 precursor prot 15 9
434792 AA649253 Hε 132458 ESTs 15 9
418036 Z37976 Hε 83337 latent transforming growth factor beta b 15 9 442787 W93048 Hs 250723 hypothetical protein MGC2747 15 9
448402 BE244226 Hs 21094 RAB18 member RAS oncogene family 15 9
402812 NM.004930* Homo εapienε capping protein 15 8
447313 U92981 Hs 18081 Homo εapienε clone DT1P1B6 mRNA, CAG rep 158
413597 AW302885 Hs 117183 ESTε 157
439677 R82331 Hs 164599 ESTε 15 7
432527 AW975028 Hs 102754 ESTs 157
413654 AA331881 Hs 75454 peroxiredoxin 3 157
418818 AA228899 Hs 101307 Homo sapiens HUT11 protein mRNA, partial 157
426501 AW043782 Hs 293616 ESTs 157
435056 AW023337 Hs 5422 glycoprotein M6B 15 7
414504 AW069181 Hs 115175 sterile alpha motif and leucine zipper c 156
443960 AI093577 Hs 255416 hypothetical protein FLJ21986 15 6
434988 AI418055 Hs 161160 ESTs 156
435380 AA679001 Hs 192221 ESTs 156
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of 156
437252 AI433833 Hs 164159 ESTs, Weakly similar to ALU1 HUMAN ALU S 156
446377 AW014022 Hs 170953 ESTs 155
425009 X58288 Hs 154151 protein tyrosine phosphatase, rxeptor t 155
415672 N53097 Hs 193579 ESTs 155
450325 AI935962 Hs 26289 ESTs 155
400294 N95796 Hs 278695 Homo sapiens prostein mRNA, complete eds 154
443674 AI081330 Hε 145008 ESTε 154
415263 AA948033 Hs 130853 ESTε 154
442081 AA401863 Hs 22380 ESTε 153
415788 AW628686 Hs 78851 KIAA0217 protein 153
445467 AI239832 Hs 15617 ESTε, Weakly similar to ALU4_HUMAN ALU S 153
436299 AK000767 Hs 5111 hypothetical protein FLJ20729 153
418693 AI750878 Hs 87409 thrombospondm 1 153
422163 AF027208 Hs 112360 prominm (mouse) like 1 153
443180 R15875 Hs 258576 claudin 12 152
432437 W07088 Hs 293685 ESTs 152
415786 AW419196 Hs 257924 hypothetical protein FLJ13782 152
446091 AW022192 Hs 200197 ESTs 152
409341 AI963376 Hs 12532 chromosome 1 open reading frame 21 152
430376 AW292053 Hs 12532 chromosome 1 open reading frame 21 15 1
434096 AW662958 Hs 75825 pleiomorphtc adenoma gene-like 1 151
453698 AA037615 Hs 42746 ESTs 151
444805 AB007899 Hs 12017 homolog of yeast ubiquitin protein ligas 15 1
427707 NM 005578 Hs 180398 LIM domain-containing preferred traπslx 151
453308 AW959731 Hs 323099 ESTs 15 1
442607 AA507576 Hs 288361 Homo sapiens cDNA FLJ22696 fis, clone H 15 1
433927 AI557019 Hs 116467 small nuclear protein PRAC 150
443162 T49951 Hs 9029 DKFZP434G032 protein 150
412490 AW803564 Hs 288850 Homo sapiens cDNA FLJ22528 fis, clone H 150
424580 AA446539 Hs 339024 ESTs, Weakly similar to A46010 X linked 150
443912 R37257 Hs 184780 ESTs 150
410297 AA148710 Hs 79914 lumican 150
431448 AL137517 Hs 334473 hypothetical protein DKFZp5640l278 149
432306 Y18207 Hs 303090 protein phosphatase 1, regulatory (mhib 149
451652 AA018968 Hs 133536 ESTs 149
406038 Y14443 Hs 88219 zinc finger protein 200 148
408784 AW971350 Hs 63386 ESTs 148
453510 AI699482 Hs 42151 ESTs 148
407894 AJ278313 Hs 41143 phosphomositide-spxific phospholipaεe 148
433908 AW298141 Hs 157975 ESTε 148
440529 AW207640 Hs 16478 Homo εapienε cDNA FLJ21718 fis, clone C 148
413249 AF167160 Hε 75251 DEAD/H (Asp-Glu-Ala-Asp/His) box binding 148
408430 S79876 Hε 44926 dipeptidylpeptidase IV (CD26, adenosme 147
430665 BE350122 Hs 157367 ESTε, Weakly similar to I78885 senne/th 147
447752 M73700 Hs 105938 Ixtotranεfemn 147
426044 AA502490 Hs 336695 ESTε 147
403362 NM 001615* Homo εapienε xtin, gamma 2, 147
427982 NM_016156 Hε 181326 KIAA1073 protem 147
407634 AW016569 Hs 136414 UDP-GlcNAc betaGal beta-1,3-N-xetylgluc 147
448362 AA641767 Hε 21015 hypothetical protein DKFZp564L0864 simil 147
433226 AW503733 Hs 9414 KIAA1488 protein 146
427472 AA522539 Hs 131250 transposon-deπved Buster3 traπεposase-l 146
453861 AI026838 Hs 30120 ESTs, Weakly similar to NUCLHUMAN NUCLE 146
458082 AW978811 Hs 314451 ESTs, Weakly similar to ALU1_HUMAN ALU S 146
409264 NM 014937 Hs 52463 KIAA0966 protein 146
432729 AK000292 Hs 278732 hypothetical protein FLJ20285 145
422270 AF114494 Hs 114062 protein tyrosine phosphatase-like (proli 145
410339 AI916499 Hs 298258 ESTs 145
431992 NM 002742 Hs 2891 protein kmase C, mu 145
424432 AB037821 Hs 146858 protocadhenn 10 145
431933 AI187057 Hs 132554 ESTs 145
440749 W22335 Hs 7392 hypothetical protein MGC3199 145
416434 AW163045 Hs 79334 nuclear fxtor, interleukin 3 regulated 145
450382 AA397658 Hε 60257 Homo sapienε cDNA FLJ13598 fis clone PL 145
407021 U52077 gb Human maπnerl traπsposaεe gene, comp 145
413786 AW613780 Hε 13500 ESTε 145
437866 AA156781 Hε 74170 metallothionein 1E (functional) 145 454078 AA601518 Hs 22209 secreted modular calcium binding protein 144
411990 AW963624 Hs 31707 ESTs, Weakly similar to YEW4 YEAST HYPOT 144
443280 AA299688 Hs 24183 ESTs 144
416836 D54745 Hs 80247 cholecystokinm 144
436860 H12751 Hs 5327 PR01914 protein 143
425174 D87450 Hs 154978 KIAA0261 protein 143
442242 AV647908 Hs 90424 Homo sapiens cDNA FLJ23285 fϊs clone H 143
443790 NM 003500 Hs 9795 acyl Coenzyme A oxidaεe 2, branched chai 143
418994 AA296520 Hs 89546 εelxtm E (endothelial adheεioπ molxul 142
419563 AA526235 Hs 193162 Homo sapieπε cDNA FLJ11983 fiε, clone HE 142
437718 AI927288 Hs 196779 ESTε 142
412828 AL133396 Hs 74621 pπon protein (p27-30) (Creutzfeld-Jakob 142
432712 AB016247 Hs 288031 εterol C5 desaturase (fungal ERG3, delta 14 2
433332 AI367347 Hs 44898 Homo sapienε clone TCCCTA00151 mRNA εequ 142
451533 NM.004657 Hs 26530 εerum depπvation response (phosphafidyl 142
424701 NM 005923 Hs 151988 mitogen-activated protein kinase kinase 141
446494 AA463276 Hs 288906 WW Domain-Containing Gene 14 1
456508 AA502764 Hs 123469 ESTs, Weakly similar to AF208855 1 BM 01 140
432251 AW972983 Hs 232165 polycythemia rubra vera 1, cell surfxe 140
426423 NM 012446 Hs 169833 single-stranded DNA-bmdiπg protein 140
442281 N34742 Hs 170065 Homo sapiens CDNA FLJ13492 fis clone PL 140
442145 AI022650 Hs 8117 erbb2 interacting protein ERBIN 139
418848 AI820961 Hs 193465 ESTs 139
447072 D61594 Hs 17279 tyrosylproteiπ sulfotranεferaεe 1 139
439518 W76326 gb zd60d04 r1 Soareε fetal heart NbHH19W 139
443967 AW294013 Hs 200942 ESTε 139
424775 AB014540 Hs 153026 SWAP-70 protein 13 9
411190 AA306342 Hs 69171 protein kinase C-like 2 139
447384 AI377221 Hs 40528 ESTs 139
444880 AW118683 Hs 154150 ESTs 139
433409 AI278802 Hs 25661 ESTs 139
423201 NM 000163 Hs 125180 growth hormone rxeptor 139
413724 AA131466 Hs 23767 hypothetical protem FLJ12666 13 9
454219 X75042 Hs 44313 v-rel avian reticuloendotheliosis viral 138
429165 AW009886 Hs 118258 prostate cancer assxiated protein 1 138
430598 AK001764 Hs 247112 hypothetical protein FLJ10902 138
444172 BE147740 Hs 104558 ESTs, Moderately similar to I38022 hypot 13 8
416774 AI005169 Hs 28274 Homo sapienε cDNA FLJ22049 fiε, clone H 138
410310 J02931 Hε 62192 coagulation factor III (thromboplaεtin, 138
428738 NM 000380 Hε 192803 xeroderma pigmentosum, complementation g 138
400296 AA305627 Hε 139336 ATP-bmding cassette, sub-family C (CFTR 138
407939 W05608 Hε 312679 ESTs, Weakly similar to A49019 dynein he 13 8
452281 T93500 Hs 28792 Homo εapienε cDNA FLJ 11041 fis, clone PL 137
408622 AA056060 Hs 202577 Homo sapienε cDNA FLJ12166 fiε clone MA 137
428054 AI948688 Hs 266619 ESTε 137
444636 T96667 Hs 17877 ESTε 137
416292 AA179233 Hs 42390 nasopharyngeal carcinoma susceptibility 137
442315 AA173992 Hs 7956 ESTs, Moderately similar to ZN91.HUMAN Z 137
452260 AA453208 Hs 28726 RAB9, member RAS oncogene family 137
428966 AF059214 Hs 194687 cholesterol 25-hydroxylase 137
450316 W84446 Hs 226434 hypothetical protein MGC4643 137
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet-x 137
443634 H73972 Hs 134460 ESTs 137
449474 AA019344 Hs 2055 ubiquit -xtivating enzyme E1 (A1S9T an 137
422278 AF072873 Hs 114218 frizzled (Drosophila) homolog 6 137
445817 NM 003642 Hs 13340 histone xetyltraπsferase 1 137
434629 AA789081 Hs 4029 glioma-amplified sequence 41 13 6
416795 AI497778 Hs 20509 HBV pX assxiated protein 8 136
410001 AB041036 Hε 57771 kallikrein 11 136
452242 R50956 Hε 159993 gycosyltraπεferaεe 136
413231 D87461 Hs 75244 BCL2-lιke 2 136
404641 NMJ21965* Homo εapieπε phoεphoglucomuta 136
428648 AF052728 Hs 188021 potaεεium voltage-gated channel, subfami 136
414279 AW021691 Hs 101067 GCN5 (general control of ammo-xid synt 136
411573 AB029000 Hε 70823 KIAA1077 protein 135
417632 R20855 Hs 5422 glycoprotein M6B 13 5
431467 N71831 Hs 256398 Homo sapienε mRNA, cDNA DKFZp434E0528 (f 135
450313 AI038989 Hs 332633 Bardet-Biedl syndrome 2 135
445472 AB006631 Hs 12784 Homo sapienε mRNA for KIAA0293 gene, par 135
419264 AA877104 Hs 293672 ESTε, Weakly similar to ALUB.HUMAN nil 13 5
418663 AK001100 Hs 41690 desmxollin 3 135
452277 AL049013 Hs 28783 KIAA1223 protein 135
447896 AI436124 Hs 294069 Homo sapiens cDNA FLJ13384 fis, clone PL 135
447082 T85314 Hs 42644 thioredoxin like 13 5
451468 AW503398 Hs 293663 ESTs, Moderately similar to I38022 hypot 134
415443 T07353 Hs 7948 ESTs 134
427212 AW293849 Hs 58279 ESTs, Weakly similar to ALU7JHUMAN ALU S 134
442113 BE622187 Hs 99670 ESTs, Weakly similar to I38022 hypotheti 133
433517 AW022133 Hs 189838 ESTs 133
430829 AW451999 Hs 194024 ESTs 133
453111 AB014598 Hε 31720 hephaestm 133
435839 AF249744 Hs 25951 Rho guanine nucleotide exchange factor ( 133
429113 D28235 Hs 196384 prostaglandm endoperoxide synthase 2 (p 133 422728 AW937826 Hε 103262 ESTs, Weakly similar to ZN91_HUMAN ZINC 133
427286 AW732802 Hε 2132 epidermal growth factor receptor pathway 133
437323 AA371145 Hs 226627 leptm rxeptor 13 2
421878 AA299652 Hs 111496 Homo sapienε cDNA FLJ11643 fiε, clone HE 13 2
433037 NM.014158 Hs 279938 HSPC067 protein 13 2
407938 AA905097 Hs 85050 phospholamban 132
400860 Target Exon 132
411031 W37943 Hs 34892 KIAA1323 protein 13 2
436797 AA731491 Hs 336454 hypothetical protein MGC14879 13 2
409277 T05558 Hs 156880 ESTs 132
434036 AI659131 Hs 197733 hypothetical protein MGC2849 132
448520 AB002367 Hs 21355 doublxortin and CaM kinase like 1 132
450755 AA010984 Hs 159464 ESTs 13 1
450649 NM 001429 Hs 25272 E1A binding protein p300 13 1
408495 W68796 Hs 237731 ESTs 13 1
429732 U20158 Hs 2488 lymphxyte cytosolic protein 2 (SH2 doma 13 1
428839 AI767756 Hs 82302 Homo sapiens cDNA FLJ14814 fis, clone NT 131
416987 D86957 Hs 80712 KIAA0202 protein 130
453006 AI362575 Hs 167133 ESTs 130
421750 AK000768 Hs 107872 hypothetical protein FLJ20761 130
415752 BE314524 Hs 78776 putative transmembrane protein 130
411529 AA430348 Hs 317596 Homo sapiens cDNA FLJ 12927 fis, clone NT 130
417318 AW953937 Hs 12891 ESTs 130
410763 AF279145 Hs 8966 hypothetical protem FU21776 129
426034 AI276989 Hs 56123 Homo sapiens cDNA FLJ13443 fis, clone PL 12 9
447966 AA340605 Hs 105887 ESTε, Weakly similar to Homolog of rat Z 129
428218 AA424266 Hs 123642 EphA3 12 9
409799 D11928 Hs 76845 phosphosenne phoεphatase like 12 9
448779 BE042877 Hs 177135 ESTs 128
448944 AB014605 Hs 22599 atrophιπ-1 interxting protein 1, xtivi 12 8
417315 AI080042 Hs 336901 nbosomal protein S24 128
429697 AW296451 Hs 24605 ESTs 128
432674 AA641092 Hs 257339 ESTs, Weakly similar to I38022 hypotheti 128
445309 AL157474 Hs 12504 likely ortholog of mouse Arkadia 128
451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 128
424806 AA382523 Hε 105689 MSTP031 protein 127
442343 AA992480 Hε 129874 ESTs 127
432244 AI669973 Hs 200574 ESTs 127
459513 AI032946 gb ox06g09 s1 Soareε fetal liver εpleen 127
452512 AW363486 Hs 337635 ESTs 127
415079 R43179 Hs 22895 hypothetical protein FLJ23548 127
422365 AF035537 Hs 115521 REV3 (yeast homolog) like, catalytic sub 127
411067 AI681006 Hs 71721 ESTs 127
442501 AA315267 Hs 23128 ESTs 127
434466 AB037829 Hs 3862 regulator of nonsense transcπptε 2, DKF 127
437052 AA861697 Hs 120591 ESTs 127
433234 AB040928 Hs 65366 KIAA1495 protein 126
453830 AA534296 Hs 20953 ESTs 126
409995 AW960597 Hs 30164 ESTs 126
414290 AI568801 Hs 71721 ESTs 126
417248 AA329449 Hs 247302 twisted gastrulatioπ 126
418624 AI734080 Hs 104211 ESTs 126
412654 AI093480 Hs 29263 hypothetical protem FLJ 11896 126
450253 AL133047 Hs 24715 Homo sapienε mRNA, cDNA DKFZp434D0215 (f 126
446619 AU076643 Hs 313 εxreted phosphoprotein 1 (osteopont , 125
427078 AI676062 Hs 111902 ESTs 125
420838 AW118210 Hs 5244 ESTε 125
449784 AW161319 Hs 12915 ESTε 12 5
431325 AW026751 Hs 5794 ESTε, Weakly similar to 2109260A B cell 12 5
415276 U88666 Hs 78353 SFRS protein kinase 2 125
426110 NM 002913 Hs 166563 replication factor C (xtivator 1) 1 (14 125
400301 X03635 Hs 1657 estrogen rxeptor 1 125
434926 BE543269 Hs 50252 mitxhondπal nbosomal protein L32 125
426316 NM 002430 Hs 268515 menmgioma (dismpted in balanced transi 125
420345 AW295230 Hs 25231 ESTs 124
432205 AI806583 Hs 125291 ESTε 124
451893 AW192083 Hs 290855 ESTε 124
435266 AK001942 Hs 4863 hypothetical protem DKFZp566A1524 124
427003 U19487 Hε 2090 prostaglaπdm E rxeptor 2 (subtype EP2) 124
404642 NM.021965* Homo εapiens phosphoglucomuta 124
414241 AA425085 Hs 4007 Sarcolemmal assxiated protein 124
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 124
420871 AA702972 Hs 65300 ESTs 124
448072 AI459306 Hs 24908 ESTs 124
441269 AW015206 Hs 178784 ESTs 123
427761 AA412205 Hs 140996 ESTs 123
425322 U63630 Hs 155637 protein k ase, DNA-activated, catalytic 123
417733 AL048678 Hs 82503 H sapienε mRNA for 3'UTR of unknown prot 123
436521 AW203986 Hs 213003 ESTs 123
408920 AL120071 Hs 48998 fibronxtiπ leucine nch transmembrane p 123
446332 AK001635 Hs 14838 hypothetical protein FLJ10773 122
453994 BE180964 Hs 165590 πbosomal protein S13 122
420397 NM 007018 Hs 97437 centrosomal protein 1 122 447471 AF039843 Hs 18676 sprouty (Drosophila) homolog 2 122
442562 BE379584 Hs 34789 dolichyl-diphosphooligosacchande protei 122
400880 NM.000611* Homo sapiens CD59 antigen p18 122
425920 AL049977 Hε 162209 claudin 8 122
419743 AW408762 Hs 5957 Homo sapiens clone 24416 mRNA sequence 122
414222 AL135173 Hs 878 sorbitol dehydrogenase 12 1
427051 BE178110 Hs 173374 Homo sapienε cDNA FLJ 10500 fiε, clone NT 12 1
452994 AW962597 Hs 31305 KIAA1547 protein 12 1
425154 NM.001851 Hs 154850 collagen type IX alpha 1 121
437124 AA554458 Hs 197751 KIAA0666 protein 12 1
411450 H49619 Hs 127301 ESTε 12 1
421559 NM 014720 Hs 105751 Ste20 related seπne/threonme kinase 121
449625 NM 014253 Hs 23796 odz (odd Oz/ten m Drosophila) homolog 1 121
419459 AW291128 Hs 278422 DKFZP586G1122 protein 121
426252 BE176980 Hs 28917 ESTs 12 1
414171 AA360328 Hs 865 RAP1A member of RAS oncogene family 121
436169 AA888311 Hs 17602 Homo sapiens cDNA FLJ12381 fis, clone MA 120
435047 AA454985 Hs 54973 cadhenn like protein VR20 120
417625 U59305 Hs 44708 Ser-Thr protein kinase related to the my 120
439820 AL360204 Hs 283853 Homo sapiens mRNA full length insert cDN 120
443646 AI085198 Hs 164226 ESTs 120
434874 N62448 Hs 293970 methylmalonate semialdehyde dehydrogenas 120
443837 AI984625 Hs 9884 spindle pole body protein 120
451640 AA195601 Hs 26771 Human DNA sequence from clone 747H23 on 120
424232 AB015982 Hs 143460 protein kinase C, nu 11 9
414555 N98569 Hs 76422 phospholipase A2 group HA (platelets, 11 9
446874 AW968304 Hs 56156 ESTs 11 9
454119 BE549773 Hs 40510 uncoupling protein 4 11 9
436746 AA730045 Hs 187866 ESTs 11 9
432359 AA076049 Hs 274415 Homo sapienε cDNA FLJ10229 fis, clone HE 11 9
416508 R39769 Hs 206088 ESTs, Moderately similarto ALU8.HUMAN A 11 8
444758 AL044878 Hs 11899 3-hydroxy 3-methylglutaryl Coenzyme A re 11 8
413991 H44725 Hs 42683 ESTs 11 8
431645 AF078849 Hs 266483 dynein light chain A 11 8
421406 AF179897 Hs 104105 Meis (mouεe) homolog 2 11 8
408826 AF216077 Hs 48376 Homo εapienε clone HB 2 mRNA εequence 11 8
424903 T26477 Hs 22883 ESTε, Weakly similar to I38022 hypotheti 11 8
412977 AA125910 Hs 191461 ESTs 11 8
426981 AL044675 Hs 173081 KIAA0530 protein 11 8
410853 H04588 Hs 30469 ESTs 11 7
444670 H58373 Hs 332938 hypothetical protein MGC5370 11 7
444381 BE387335 Hs 283713 ESTs, Weakly similar to S64054 hypotheti 11 7
434398 AA121098 Hs 3838 εerum inducible kinase 11 7
438032 BE045624 Hs 152992 ESTs 11 7
433212 BE218049 Hs 121820 ESTs 11 6
424330 AW073953 Hs 333396 Homo sapienε cDNA FLJ13596 fis, clone PL 11 6
452679 Z42387 Hs 83883 transmembrane prostate androgen induced 11 6
430929 AA489166 Hs 156933 ESTs 11 6
423782 AI472209 Hs 323117 ESTε 11 6
425770 NM 014363 Hs 159492 εpaεtic ataxia of Charlevoix-Saguenay (ε 11 6
437108 AA434054 Hs 80624 hypothetical protein MGC2560 11 6
430200 BE613337 Hs 234896 geminm 11 5
453857 AL080235 Hs 35861 DKFZP586E1621 protein 11 5
411096 U80034 Hs 68583 mitochondnal intermediate peptidase 11 5
422805 AA436989 Hs 121017 H2A histone family, member A 11 5
422538 NM 006441 Hs 118131 5,10-methenyItetrahydrofolate synthetaεe 11 5
412677 AW029608 Hs 17384 ESTε 11 5
421896 N62293 Hs 45107 ESTε 11 5
453930 AA419466 Hs 36727 hypothetical protein FU10903 11 5
443123 AA094538 Hs 272808 putative transcnption regulation nuclea 11 5
415293 R49462 Hs 106541 ESTs 11 5
443161 AI038316 gb ox48c08 x1 Soares total fetus Nb2HF8 11 5
420185 AL044056 Hs 158047 ESTε 11 5
445527 W39694 Hs 83286 ESTε, Weakly εimilar to S14747 εphmgomy 11 5
428829 R14050 Hs 194051 Homo εapieπs mRNA cDNA DKFZp566B213 (fr 11 5
416852 AF283776 Hs 80285 Homo sapienε mRNA cDNA DKFZp586C1723 (f 11 5
449919 AI674685 Hs 200141 ESTs 11 5
414844 AA296874 Hs 77494 deoxyguanosme kinaεe 11 5
449543 AF070632 Hs 23729 Homo εapiens clone 24405 mRNA sequence 11 4
429784 M89796 Hs 30 membrane-spanning 4-domams, εubfamily A 11 4
407786 AA687538 Hε 38972 tetraεpan 1 11 4
414407 AA147026 Hε 76704 ESTε 11 4
441247 AW118681 Hs 128051 Homo εapiens thymic stromal lymphopoieti 11 4
456804 AI421645 Hs 139851 caveolm 2 11 4
422546 AB007969 Hs 301478 KIAA0500 protein 11 4
417350 U50928 Hs 82001 polycystic kidney disease 2 (autosomal d 11 4
417683 AW566008 Hs 239154 ankyπn repeat family A (RFXANK like), 11 4
424800 AL035588 Hs 153203 MyoD family inhibitor 11 4
433577 AW007080 Hs 8817 ESTs 11 4
453935 AI633770 Hs 42572 ESTs 11 4
415060 AJ223810 Hs 43213 ESTs, Weakly similar to IEFS.HUMAN TRANS 11 4
425710 AF030880 Hs 159275 solute earner family, member 4 11 3
448766 AI473827 Hs 31793 ESTs 11 3 444151 AW972917 Hs 128749 alpha-methylacyl CoA racemase 11 3
410108 AA081659 Hs 318775 OSBP-related protein 6 11 3
418450 R84397 Hs 193651 ESTs, Weakly similar to alternatively sp 11 3
415457 AW081710 Hs 7369 ESTε, Weakly εimilar to ALU1.HUMAN ALU S 11 3
452110 T47667 Hs 28005 Homo εapienε cDNA FLJ11309 fis, clone PL 11 3
414212 AA136569 Hs 10848 KIAA0187 gene product 11 3
401519 C15000476* gι|12737279|ref|XP_0121631| 11 3
458509 AA654650 Hs 282906 ESTs 11 2
416913 AW934714 gb RC1-DT0001-031299 011 a11 DT0001 Homo 11 2
452784 BE463857 Hs 151258 hypothetical protein FLJ21062 11 2
436758 AW977167 Hs 155272 ESTs 11 2
409401 AI201895 Hs 181309 proteasome (prosome, macropain) subunit, 11 2
434715 BE005346 Hs 116410 ESTs 11 2
427283 AL119796 Hs 174185 xtonuclxtide pyrophosphatase/phosphodi 11 2
428342 AI739168 Hs 131798 Homo sapiens cDNA FLJ13458 fis, clone PL 11 2
419465 AW500239 Hs 21187 Homo sapienε cDNA FLJ23068 fis, clone L 11 2
430519 AF129534 Hs 49210 F-box only protein 4 11 2
418838 AW385224 Hs 35198 xtonudeotide pyrophosphatase/phosphodi 11 1
429163 AA884766 gb am20a10s1 Soares NFL.T GBC S1 Homos 11 1
434158 T86534 Hs 14372 ESTs 11 1
414341 D80004 Hs 75909 KIAA0182 protein 11 1
414650 AA150435 Hs 72063 ESTs 11 1
448475 BE613134 Hs 247474 hypothetical protein FLJ21032 11 1
437575 AW954355 Hs 36529 hypothetical protein MGC11242 11 1
423566 AW976434 Hs 3623 hypothetical protein FLJ11220 11 1
425289 AW139342 Hs 155530 interferon gamma-inducible protein 16 11 1
452598 AI831594 Hs 68647 ESTs, Weakly similar to ALU7.HUMAN ALU S 11 1
417433 BE270266 Hs 82128 5T4 oncofetai trophoblast glycoprotein 11 0
438379 N23018 Hs 171391 C-terminal binding protein 2 11 0
433230 AW136134 Hs 220277 ESTs 11 0
412622 AW664708 Hs 171959 ESTs 11 0
450353 AI244661 Hs 103296 ESTs, Weakly similar to S65657 alpha 1 C- 11 0
434349 NM 015678 Hs 3821 neurobeachm 11 0
430261 AA305127 Hs 237225 hypothetical protein HT023 11 0
420544 AA677577 Hs 98732 Homo εapienε Chromosome 16 BAC clone CIT 11 0
424099 AF071202 Hs 139336 ATP-bmding cassette, sub-family C (CFTR 11 0
442082 R41823 Hs 7413 ESTε 11 0
422890 Z43784 Hs 75893 ankyπn 3, node of Ranvier (ankyπn G) 11 0
437162 AW005505 Hs 5464 thyroid hormone rxeptor coxtivating pr 11 0
450244 AA007534 Hs 125062 ESTε 11 0
417169 R13550 Hs 246773 ESTs 11 0
421481 AW391972 Hs 104696 KIAA1324 protem 109
431576 M76665 Hs 275215 hydroxysteroid (11-beta) dehydrogenase 1 109
408988 AL119844 Hs 49476 Homo sapiens clone TUA8 Cπ-du-chat regi 109
439706 AW872527 Hs 59761 ESTs, Weakly similarto DAP1.HUMAN DEATH 109
435133 AJ010482 Hs 31412 Homo εapiens cDNA FLJ 11422 fis, clone HE 109
433658 L03678 Hs 156110 immunoglobulin kappa constant 109
428364 AA426565 Hs 311103 ESTs, Moderately similar to ALU1 HUMAN A 109
441540 C01367 Hs 127128 ESTs 109
431154 AW971228 Hs 290259 ESTs, Weakly similar to I38022 hypotheti 109
416777 AF146760 Hs 79844 DKFZP564M1416 protein 109
439556 AI623752 Hs 163603 ESTs 109
428280 H05541 Hs 183428 sarcoεpan (Kraε oncogeπe-assxiated gene 108
453942 AW190920 Hs 19928 hypothetical protein SP329 108
447982 H22953 Hs 137551 ESTs 108
422779 AA317036 Hs 118787 transforming growth factor, beta induced 108
447595 AW379130 Hs 18953 phosphodiesterase 9A 108
427115 AW972853 Hs 112237 ESTs 108
448019 AW947164 Hs 195641 ESTs, Moderately similar to I38022 hypot 10 8
419326 W94915 Hs 42419 ESTs 108
435163 AA668884 Hs 19155 ESTs 108
417578 T91443 Hs 193963 ESTs 108
407930 AA045847 Hs 188361 Homo sapienε cDNA FLJ12807 fis, clone NT 108
450206 AI796450 Hs 201600 ESTs 108
426413 AA377823 gb EST90805 Synovial εarcoma Homo sapien 108
421977 W94197 Hs 110165 πbosomal protein L26 homolog 108
437967 BE277414 Hs 5947 el transforming oncogene (deπved from 108
408243 Y00787 Hs 624 interleukin 8 108
439492 AF086310 Hε 103159 ESTε 108
413492 D87470 Hε 75400 KIAA0280 protein 108
436962 AW377314 Hs 5364 DKFZP564I052 protein 108
435572 AW975339 Hs 239828 ESTε, Weakly similar to GAG2.HUMAN RETRO 108
422583 AA410506 Hs 27973 KIAA0874 protein 108
417665 AW852858 Hs 22862 ESTs 107
433285 AW975944 Hs 237396 ESTs 107
419693 AA133749 Hs 301350 FXYD domain-containing ion transport reg 107
424878 H57111 Hs 221132 ESTs 107
449659 R60031 Hs 198899 eukaryotic translation initiation factor 107
415910 U20350 Hs 78913 chemokine (C-X3 C) receptor 1 107
433556 W56321 Hs 111460 calcium/calmodul dependent protein km 107
452241 AL050204 Hs 28540 Homo sapiens mRNA, cDNA DKFZp586F1223 (f 107
450330 AW500775 Hs 24817 hypothetical protein FLJ20136 107
430589 AJ002744 Hs 246315 UDP-N-xetyl alpha D-galactosamme polyp 107 433923 AI823453 Hε 146625 ESTs 107
418196 AI745649 Hs 26549 KIAA1708 protein 107
416155 AI807264 Hs 205442 ESTs, Weakly similar to T34036 hypotheti 107
430057 AW450303 Hs 2534 bone morphogeπetic protein receptor, typ 107
429350 AI754634 Hs 131987 ESTs 107
418601 AA279490 Hs 86368 calmegm 106
437267 AW511443 Hs 258110 ESTs 106
432169 Y00971 Hs 2910 phosphoπbosyl pyrophosphate synthetase 106
421982 AF206019 Hε 110347 REV1 (yeast homolog)- like 106
414085 AA114016 Hε 75746 aldehyde dehydrogenase 1 family, member 10 6
418662 AI801098 Hs 151500 ESTs 106
449685 AW296669 Hs 66095 ESTs 106
441111 AI806867 Hs 126594 ESTs 106
436671 AW137159 Hs 146151 ESTs 106
447974 R76886 gb yι64b03 ε1 Soareε placenta Nb2HP Homo 106
417916 NM.006416 Hs 82921 solute carrier family 35 (CMP-sialic xi 106
424562 AI420859 Hs 150557 basic transcription element binding prot 106
408331 NM.007240 Hs 44229 dual specificity phosphatase 12 106
443015 R33261 Hs 6614 ESTs, Weakly similar to A43932 mucin 2 p 106
439584 AA838114 Hs 221612 ESTs 106
426298 AW965058 Hs 111583 ESTs, Weakly similar to I38022 hypotheti 106
420929 AI694143 Hs 296251 programmed cell death 4 106
418318 U47732 Hs 84072 transmembrane 4 superfamily member 3 106
414565 AA502972 Hs 183390 hypothetical protein FLJ13590 106
418329 AW247430 Hs 84152 cystathionine-beta-synthase 106
424433 H04607 Hs 9218 ESTs 106
420230 AL034344 Hs 284186 forkhead box C1 106
419441 AW023731 Hs 274368 MSTP032 protein 106
426011 AW996096 Hs 58924 ESTs, Weakly similar to JC5594 jerky gen 106
451900 AB023199 Hs 27207 KIAA0982 protein 106
424692 AA429834 Hs 151791 KIAA0092 gene product 106
439999 AA115811 Hs 6838 ras homolog gene family, member E 105
424368 AB037766 Hs 146085 KIAA1345 protein 105
402076 C5002020* gι|1082876|pιrIjS55467 tropomy 105
413886 AW958264 Hs 103832 similar to yeast Upf3, variant B 105
445041 T64183 Hs 282982 solute earner 105
428927 AA441837 Hs 90250 ESTs 105
414831 M31158 Hs 77439 protein kmase, cAMP dependent, regulato 105
407902 AL117474 Hs 41181 Homo sapieπε mRNA, cDNA DKFZp727C191 (fr 105
426429 X73114 Hs 169849 myoεm binding protein C, εlow-type 105
452055 AI377431 Hs 141693 hypothetical protein MGC10858 105
438913 AI380429 Hs 172445 ESTε 105
443684 AI681307 Hs 55098 ESTε 105
429281 AA830856 Hs 29808 Homo εapienε cDNA FLJ21122 fiε, clone C 105
421040 AA715026 Hs 135280 ESTε 105
425277 NM.001241 Hs 155478 cyclin T2 105
418564 AA631143 Hs 278695 Homo εapiens prastein mRNA, complete eds 105
440099 AL080058 Hs 6909 DKFZP564G202 protein 105
434958 T99949 Hs 303428 Homo sapienε cDNA FLJ14832 fiε, clone OV 105
419972 AL041465 Hs 182982 golgm 67 105
416182 NM.004354 Hs 79069 cyclin G2 104
418365 AW014345 Hs 161690 ESTε 104
452286 AI358570 Hs 123933 ESTε, Weakly similar to ZN91.HUMAN ZINC 104
430361 AI033965 Hs 239926 sterol C4-methyl oxidase like 104
446716 AA436575 Hs 16602 ESTs 104
419544 AI909154 gb QV-BT200-010499-007 BT200 Homo sapien 104
433023 AW864793 Hs 87409 thrombospondm 1 104
409151 AA306105 Hs 50785 SEC22, vesicle trafficking protein (S c 104
449115 AW959952 Hs 37528 ESTε, Weakly similar to AF090944 1 PRO06 104
445715 AB012958 Hs 13137 UV radiation resiεtance aεεxiated gene 104
443228 W24781 Hs 293798 KIAA1710 protein 104
424051 AL110203 Hs 138411 Homo εapieπε mRNA, cDNA DKFZp586J1922 (f 104
453496 AA442103 Hε 33084 εolute earner family 2 {facilitated glu 104
452741 BE392914 Hs 30503 Homo sapiens cDNA FLJ11344 fis, clone PL 104
428728 NM 016625 Hs 191381 hypothetical protein 104
423905 AW579960 Hs 135150 lung type-l cell membrane-assxiated gly 104
413328 Y15723 Hs 75295 guanylate cyclase 1, soluble, alpha 3 103
453020 AL162039 Hs 31422 Homo sapiens mRNA, cDNA DKFZp434M229 (fr 103
411359 H86088 Hs 22635 ESTs 103
420000 AB036063 Hs 94262 p53-ιπducιble πbonucleotide reductase s 103
412262 W26406 Hs 295923 seven in absentia (Drosophila) homolog 1 103
419875 AA853410 Hs 93557 proenkephalin 103
414422 AA147224 Hs 337232 Ho x box A13 103
426581 AB040956 Hs 135890 KIAA1523 protein 103
424649 BE242035 Hs 151461 embryonic xtoderm development 103
407317 AI204033 Hs 271461 ESTs, Weakly similar to I38022 hypotheti 103
440426 AI159800 Hs 7181 Homo sapienε cDNA FLJ13663 fis, clone PL 103
433495 AW373784 Hs 71 alpha-2-qlycoproteιn 1 , zinc 103
423250 BE061916 Hs 125849 chromosome 8 open reading frame 2 103
438459 T49300 Hs 35304 Homo sapiens cDNA FLJ13655 fis, clone PL 103
451593 AF151879 Hs 26706 CGI-121 protein 103
435106 AA100847 Hs 193380 ESTs, Highly similar to AF174600 1 F-box 103
438157 AW137011 Hs 49576 ESTs 103 443181 AI039201 Hs 283316 ESTs 103
449125 AI671439 Hs 196029 Homo sapienε mRNA for KIAA1657 protein 102
411479 AW848047 gb IL3 CT0214-291299 052 A12 CT0214 Homo 102
446553 AB021179 Hs 15299 HMBA inducible 102
418278 AI088489 Hs 83937 hypothetical protem 102
419791 AI579909 Hs 105104 ESTs 102
418866 T65754 gb yd 1c07 s1 Stratagene lung (937210) H 102
413753 U17760 Hs 75517 laminin, beta 3 (nicein (125kD), kalmm 102
445564 AB028957 Hs 12896 KIAA1034 protein 102
435021 AA922192 Hs 54709 ESTs 10 2
457498 AI732230 Hs 191737 ESTs 102
425628 NM 004476 Hs 1915 folate hydrolase (prostate spxific memb 102
419589 AW973708 Hs 201925 Homo sapiens cDNA FLJ13446 fis, clone PL 102
446162 AI631319 Hs 63841 hypothetical protein DKFZp434E2318 102
414523 AU076633 Hs 76353 εeπne (orcyεteme) proteinase inhibito 102
427393 AB029018 Hs 177635 KIAA1095 protein 101
408741 M73720 Hs 646 carboxypeptidase A3 (mast cell) 101
437743 AI383497 Hs 131811 ESTs, Weakly similar to ALULHUMAN ALU S 101
414888 AL039185 Hs 77558 thyroid hormone rxeptor interactor 7 101
448172 N75276 Hs 135904 ESTs 101
421863 AI952677 Hs 108972 Homo sapiens mRNA, cDNA DKFZp434P228 (fr 10 1
444618 AV653785 Hs 173334 ELL-RELATED RNA POLYMERASE II, ELONGAT I 10 1
413450 Z99716 Hs 75372 N-acetylgalactosamimdase, alpha- 101
413431 AW246428 Hs 75355 ubiquitin-conjugatmg enzyme E2N (homolo 101
410150 AW382942 Hs 6774 ESTs 101
444100 AA383343 Hs 22116 CDC14 (cell division cycle 14, S cerevi 101
448148 NM 016578 Hε 20509 HBV pX asεociated protein 8 101
443476 AW068594 Hs 133878 ESTε, Weakly similar to YCD1.HUMAN HYPOT 101
433345 AI681545 Hs 152982 hypothetical protein FLJ13117 101
423681 AB023215 Hs 131525 Homo sapiens mRNA cDNA DKFZp434E199 (fr 101
450205 AI219748 Hs 11356 ESTs 10 1
408374 AW025430 Hs 155591 forkhead box F1 100
446035 NM.006558 Hs 13565 Sam68 like phosphotyroεme protein, T-ST 100
432589 AL135725 Hs 131708 ESTε 100
435604 AA625279 Hs 26892 uncharxteπzed bone marrow protein BM04 100
411997 AW673478 Hs 108323 ubiquitin conjugating enzyme E2E 2 (homo 100
419672 AA465113 Hs 23853 ESTε, Weakly similar to A34615 profilagg 100
444564 AI167877 Hs 143716 ESTs 100
426931 NM.003416 Hs 2076 zinc finger protein 7 (KOX 4, clone HF 1 100
451424 AI862026 Hs 302810 Novel human gene mapping to chomosome 20 100
433730 AK002135 Hs 3542 hypothetical protein FLJ 11273 100
431616 AA508552 Hε 195839 ESTε, Weakly similar to I38022 hypotheti 10 0
427359 AW020782 Hs 79881 Homo sapieπε cDNA FLJ23006 fiε, clone L 100
425683 AB037813 Hs 159200 hypothetical protein DKFZp762K222 100
442760 BE075297 Hs 6614 ESTs, Weakly similar to A43932 mucin 2 p 100
418884 AA230228 Hs 59197 ESTs 100
444821 AA053564 Hs 12040 STE20-lιke kmase 99
451989 AF169797 Hs 27413 adaptor protein containing pH domain, PT 99
439731 AI953135 Hs 45140 hypothetical protein FLJ14084 99
453127 AI696671 Hs 294110 ESTs 99
435706 W31254 Hs 7045 GL004 protein 99
410748 BE383816 Hs 12532 chromoεome 1 open reading frame 21 99
418250 U29926 Hs 83918 adenoεme monophosphate deammase (isofo 99
408832 AW085690 Hs 63428 ESTs, Weakly similar to Z195 HUMAN ZINC 99
418339 AA639902 Hs 104215 ESTs, Moderately similar to SPCN.HUMAN S 99
452367 U71207 Hs 29279 eyes absent (Drosophila) homolog 2 99
432887 AI926047 Hs 162859 ESTs 99
430291 AV660345 Hs 238126 CGI-49 protein 99
440370 AA884000 Hs 8173 hypothetical protein FLJ 10803 99
412350 AI659306 Hs 73826 protein tyrosine phosphatase, non rxept 99
428825 AI084336 Hs 128783 ESTs, Weakly similar to I38022 hypotheti 99
441054 AA913591 Hs 126480 ESTs 99
415875 AA894876 Hs 5687 protein phosphatase 1B (formerly 2C), ma 99
453078 AF053551 Hs 31584 metaxm 2 98
409203 AA780473 Hs 687 cytxhrome P450, subfamily IVB, polypept 98
446720 AI439136 Hs 140546 ESTs 98
418475 AI858732 Hs 30443 εeπtππ/SUMO-εpecific proteaεe 98
417708 N74392 Hs 50495 ESTε 98
407870 AB032990 Hs 40719 hypothetical protein KIAA1164 98
420568 F09247 Hs 247735 protocadhenn alpha 10 98
418858 AW961605 Hs 21145 hypothetical protein RG083M052 98
453548 AL079983 Hs 116774 integnn, alpha 1 98
427308 D26067 Hs 174905 KIAA0033 protein 98
434579 T55958 gb yb35f05 r1 Stratagene fetal εpleen (9 98
434826 AF155661 Hs 22265 pyruvate dehydrogenaεe phosphatase 98
427528 AU077143 Hs 179565 minichromosome maintenance deficient (S 98
413174 AA723564 Hs 191343 ESTs 98
443250 A1041530 Hs 132107 ESTs 98
451957 AI796320 Hs 10299 Homo εapieπε cDNA FLJ13545 fiε, clone PL 98
451406 AI694320 Hs 6295 ESTε, Weakly similar to T17248 hypotheti 98
422299 AK000181 Hs 114556 hypothetical protein FLJ20174 98
427635 BE397988 Hs 179982 tumor protein p53 binding protein 98
416533 BE244053 Hs 79362 retinoblastoma-like 2 (p130) 98 439091 AA830144 Hs 135613 ESTs, Moderately similar to I38022 hypot 98
418575 AA225313 Hs 222886 ESTs, Weakly similar to TRHY.HUMAN TRICH 97
432426 AW973152 Hs 31050 ESTs 97
404571 NM.015902* Homo εapienε progestm induce 97
444427 H25094 Hs 293663 ESTs, Moderately similar to I38022 hypot 97
439183 AW970600 Hs 303261 ESTs 97
432886 BE159028 Hs 279704 chromatin accessibility complex 1 97
432689 AB018320 Hs 278626 Arg/Abl interacting protein ArgBP2 97
417333 AL157545 Hs 42179 bromodomam and PHD finger containing, 3 97
429302 AU076674 Hs 198899 eukaryotic translation initiation factor 97
412324 AW978439 Hs 69504 ESTε 97
422072 AB018255 Hs 111138 KIAA0712 gene product 97
431318 AA502700 Hs 293147 ESTε, Moderately similar to A46010 X lin 97
417171 BE613486 Hs 81412 lipm 1 97
421709 AA159394 Hs 107056 CED 6 protein 97
415156 X84908 Hε 78060 phosphorylase kinase, beta 97
436446 AW016809 Hs 323795 ESTε 97
447482 AB033059 Hs 18705 KIAA1233 protein 97
439726 AW449893 Hs 293707 ESTs, Weakly similar to I38598 zinc fiπg 97
429525 N92540 Hs 205353 ectonucleoside tπphosphate diphosphohyd 97
409190 AU076536 Hs 50984 sarcoma amplified sequence 96
419111 AA234172 Hs 137418 ESTε 96
452487 AW207659 Hs 6630 Homo sapieπε cDNA FLJ13329 fis, clone OV 96
416039 AA376989 Hs 78989 alcohol dehydrogenase 5 (class III), chi 96
408239 AA053401 Hε 271827 ESTs, Moderately similar to ALU7.HUMAN A 96
419241 AA523939 Hs 165258 ESTs 96
409752 AW963990 gb EST376063 MAGE resequenceε, MAGH Homo 96
453894 AW937825 Hs 56847 Homo sapiens cDNA FLJ12874 fis, clone NT 96
439671 AW162840 Hs 6641 kmeεin family member 5C 96
407230 AA157857 Hs 182265 keratin 19 96
426083 AW962712 Hs 126712 ESTε, Weakly similar to AF191020 1 E2IG5 96
452221 C21322 Hs 288057 hypothetical protem FLJ22242 96
434263 N34895 Hs 44648 ESTs 96
412766 BE544475 Hs 54347 ESTs 96
418723 AA504428 Hs 10487 Homo sapiens, clone IMAGE 3954132, mRNA 96
443970 AI280341 Hs 166571 ESTs 96
424534 D87682 Hε 150275 KIAA0241 protein 96
419407 AW410377 Hε 41502 hypothetical protein FLJ21276 96
447889 AW469180 Hs 170651 ESTs 95
429504 X99133 Hs 204238 lipocalin 2 (oncogene 24p3) 95
433165 AA578904 Hs 292437 ESTs 95
418700 AI963808 Hs 86970 ESTs, Moderately similar to ALU5.HUMAN A 95
440282 BE262386 Hs 7137 cloneε 23667 and 23775 zinc finger prote 95
411630 U42349 Hs 71119 Putative proεtate cancer tumor suppresεo 95
408915 NM 016651 Hs 48950 heptacellular carcinoma novel gene-3 pro 95
448552 AW973653 Hs 20104 hypothetical protein FLJ00052 95
432682 AI376400 Hs 159588 ESTε 95
435803 Z44194 Hs 4994 tranεducer of ERBB2, 2 95
437444 H46008 Hs 31518 ESTs 95
410252 AW821182 Hs 61418 microfibrillar-assxiated protein 1 95
438497 AA808725 Hs 291712 ESTs, Weakly similar to 138022 hypotheti 95
449226 AB002365 Hs 23311 KIAA0367 protein 94
449465 NM.004380 Hs 23598 CREB binding protein (Rubinstein-Taybi ε 94
420969 AI636310 Hs 28310 ESTs 94
449845 AW971183 Hs 9683 DnaJ (Hsp40) homolog, εubfamily C, membe 94
434415 BE177494 gb RC6-HT0596 270300 011-005 HT0596 Homo 94
420805 L10333 Hs 99947 reticulon 1 94
415083 AI632683 Hs 27179 Homo εapienε cDNA FU12933 fiε, clone NT 94
430387 AW372884 Hs 240770 nuclear cap binding protein subunit 2, 2 94
445280 AW055063 Hs 306088 v-crk avian sarcoma virus CT10 oncogene 94
425657 T89839 Hs 119471 ESTs 94
428250 AW809208 Hs 183297 DKFZP566F2124 protein 94
453293 AA382267 Hs 10653 ESTs 94
412446 AI768015 Hs 92127 ESTs 94
441102 AA973905 Hs 331328 intermediate filament protein syncoilin 94
421689 N87820 Hs 106826 KIAA1696 protein 94
448073 W19789 Hs 336635 Homo sapiens, clone IMAGE 4179482, mRNA 94
422244 Y08890 Hs 113503 karyophenn (importin) beta 3 94
452323 W44356 Hs 292812 ESTs, Weakly similar to T33468 hypotheti 94
441499 AW298235 Hε 101689 ESTs 94
420184 AA188408 Hs 95665 hypothetical protein 94
420061 AW024937 Hs 29410 ESTε 94
420337 AW295840 Hs 14555 Homo sapiens cDNA FLJ21513 fis, clone C 94
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 93
450580 N40087 Hs 15248 ESTs 93
419926 AW900992 Hs 93796 DKFZP586D2223 protein 93
421928 AF013758 Hs 109643 polyadeπylate binding protein interactin 93
412639 AW961284 Hε 296235 ESTs 93
429786 AL080232 Hs 220696 Homo εapienε mRNA, cDNA DKFZp586A061 (fr 93
446131 NM.000929 Hs 290 phospholipase A2, group V 93
451418 BE387790 Hs 26369 hypothetical protein FLJ20287 93
416658 U03272 Hs 79432 fibπllin 2 (congenital coπtractural ara 93
425139 AW630488 Hs 325820 protease, senne, 23 93 448807 AI571940 Hs 7549 ESTs 93
412505 AA974491 Hs 21734 ESTs 93
412314 AA825247 Hs 250899 heat shxk factor binding protein 1 93
445704 AI493742 Hs 165210 ESTε, Moderately similar to I38022 hypot 93
402855 NM 001839* Homo sapiens calpoπin 3, acid 93
428465 AW970976 Hs 293653 ESTs 93
422564 AI148006 Hs 222120 ESTs 93
430027 AB023197 Hs 227743 KIAA0980 protein 92
450680 AF131784 Hs 25318 Homo sapiens clone 25194 mRNA sequence 92
424850 AA151057 Hs 153498 chromosome 18 open reading frame 1 92
433862 D86960 Hs 3610 KIAA0205 gene product 92
429227 AI961456 Hs 21275 hypothetical protein FLJ11011 92
401558 ENSP00000220478* SECRETOGRANIN III 92
428634 AA811845 Hs 106290 Kelch motif containing protein 92
437678 AA829860 Hs 122834 ESTs 92
416653 AA768553 Hs 74170 metallothionem 1E (functional) 92
431117 AF003522 Hs 250500 delta (Drosophila) like 1 92
450506 NM 004460 Hs 418 fibroblast activation protein, alpha 92
431187 AW971146 Hs 293187 ESTs 92
421202 AF193339 Hs 102506 eukaryotic translation initiation factor 9 1
429597 NM.003816 Hs 2442 a disintegnn and metalloprotemase doma 9 1
430669 AW969657 Hs 291029 ESTs 9 1
435869 AF255910 Hs 54650 junctional adhesion molecule 2 91
448822 BE149845 Hs 289038 hypothetical protem MGC4126 91
456161 BE264645 Hε 282093 hypothetical protein FLJ21918 91
423800 AA331156 gb EST35034 Embryo, 6 week, subtracted ( 91
432189 AA527941 gb nh30c04 s1 NCI CGAP_Pr3 Homo sapiens 91
434361 AF129755 Hε 117772 ESTs 91
443247 BE614387 Hs 333893 c-Myc target JP01 9 1
419879 Z17805 Hs 93564 Homer, neuronal immediate early gene, 2 9 1
411928 AA888624 Hs 197289 rab3 GTPase activating protein, non-cata 91
448704 AW080932 Hs 249247 heterogeneous nuclear protein similar to 91
448430 AI500642 Hs 289067 Homo sapieπε cDNA FLJ11404 fis clone HE 91
451246 AW189232 Hs 39140 cutaneous T-cell lymphoma tumor antigen 9 1
418821 AA436002 Hs 183161 ESTs 91
427213 AW007211 Hs 16131 hypothetical protein FLJ12876 9 1
419103 Z40229 Hs 96423 hypothetical protein FLJ23033 91
450654 AJ245587 Hs 25275 Kruppel type zinc finger protein 9 1
434194 AF119847 Hs 283940 Homo sapieπε PR01550 mRNA partial eds 9 1
447033 AI357412 Hs 157601 ESTs 90
420757 X78592 Hs 99915 androgen rxeptor (dihydrotestosteroπe r 90
428593 AW207440 Hs 185973 degenerative εpermatxyte (homolog Droso 90
430223 NM 002514 Hs 235935 nephroblastoma overexpressed gene 90
444984 H15474 Hs 132898 fatty acid desaturase 1 90
445674 BE410347 Hs 13063 transcription factor CA150 90
430294 AI538226 Hs 32976 guanine nucleotide binding protein 4 90
419852 AW503756 Hs 286184 hypothetical protein dJ551D25 90
440349 AA884196 Hs 31476 Homo sapienε cDNA FLJ13872 fis, clone TH 90
432161 AK000400 Hs 292807 ESTε, Weakly similar to envelope [H sapi 90
405523 C8001409* gι|7441226|pιr||S31212collage 90
416662 T25853 Hs 7538 ESTs 90
422763 AA033699 Hs 83938 ESTs, Moderately similar to MAS2JHUMAN M 90
446183 AA354991 Hε 14222 Homo sapienε mRNA, cDNA DKFZp761P019 (fr 90
432897 AF155099 Hs 279780 NY-REN-18 antigen 90
448988 Y09763 Hs 22785 gamma-aminobutyπc xid (GABA) A rxepto 89
449523 NM_000579 Hs 54443 chemokine (C-C motif) rxeptor 5 89
407204 R41933 Hs 140237 ESTs, Weakly similarto ALU1JHUMAN ALU S 89
413554 AA319146 Hs 75426 s∞retogranin II (chromogranm C) 89
414917 C04863 Hs 47191 ESTε 89
434539 AW748078 Hs 214410 ESTs, Weakly similar to MUC2_HUMAN MUCIN 89
441805 AA285136 Hs 301914 neuronal spxific transcnption fxtor D 89
412530 AA766268 Hs 266273 hypothetical protein FLJ 13346 89
424683 N87519 Hs 27196 ESTs 89
426158 NM.001982 Hs 199067 v-erb-b2 avian erythroblastic leukemia v 89
413132 NM 006823 Hs 75209 protein kinase (cAMP-dependent, catalyti 89
426490 NM 001621 Hs 170087 aryl hydrxarbon rxeptor 89
446896 T15767 Hs 22452 Homo sapienε mRNA for KIAA1737 protein, 89
441079 AW150697 Hs 107418 ESTε 89
437231 BE303000 Hs 288929 hypothetical protein FLJ 13258 similar to 89
431316 AA502663 Hs 145037 ESTs 89
403137 NM 005381* Homo sapiens nucleol (NCL), 89
433628 AI821784 Hs 188578 ESTs 89
418489 U76421 Hs 85302 adenosme deammase, RNA-spxific, B1 (h 89
453344 BE349075 Hs 44571 ESTs 89
410227 AB009284 Hs 61152 exostoses (multιple)-lιke 2 89
417173 U61397 Hs 81424 ubiquitin like 1 (εenlππ) 89
408161 AW952912 Hs 300383 hypothetical protein MGC3032 89
420495 AI338247 Hs 98314 Homo sapiens mRNA, cDNA DKFZp586L0120 (f 89
433213 AW665130 Hs 137190 ESTs 89
451573 AW130351 Hs 243549 ESTs 89
408393 AW015318 Hs 23165 ESTε 88
434725 AK000796 Hs 4104 hypothetical protein 88
418876 AA740616 gb ny97f11 ε1 NCI_CGAP_GCB1 Homo sapiens 88 444558 AW181975 Hs 165892 ESTs 88
417355 D13168 Hs 82002 endothelin receptor type B 88
424084 AI940675 Hs 20914 hypothetical protein FLJ23056 88
431706 AI816086 Hs 296341 adenylyl cyclase associated protein 2 88
424956 AW198103 Hs 158154 ESTs, Weakly similar to granule cell mar 88
441866 BE464341 Hε 21201 neclm 3, DKFZP566B0846 protein 88
444647 H14718 Hε 11506 Human clone 23589 mRNA sequence 88
444858 AI199738 Hε 208275 ESTs, Weakly similar to ALUA HUMAN mi 88
409643 AW450866 Hε 257359 ESTs 88
428647 AA830050 Hs 124344 ESTs 88
412330 NM 005100 Hs 788 A kinase (PRKA) anchor protein (gravm) 88
410275 U85658 Hs 61796 transcription factor AP-2 gamma (activat 88
425465 L18964 Hs 1904 protein kinase C, iota 88
424113 A1743880 Hs 12876 ESTs 88
459324 AW080953 gb xc28c12 x1 NCI CGAP Co18 Homo sapiens 88
451684 AF216751 Hs 26813 CDA14 88
451244 AW008798 Hε 267448 hypothetical protein FLJ20039 88
439170 AA332365 Hs 165539 ESTs, Weakly similarto I38022 hypotheti 88
424238 AA337401 Hs 137635 ESTs 88
449686 AW072813 Hs 270868 ESTε, Moderately similar to ALU4.HUMAN A 88
440658 H29142 Hs 143032 ESTs, Weakly similar to neuronal thread 88
410870 U81599 Hs 66731 homeo box B13 88
458229 AI929602 Hs 177 phosphatidylinositol glycaπ, class H 88
429831 AA564489 Hε 137526 ESTs 88
453468 W00712 Hε 32990 DKFZP566F084 protein 88
428340 AF261088 Hε 154721 acomtase 1, soluble 88
453345 AA302862 Hε 90063 neurocalcin delta 88
452206 AW340281 Hε 33074 Homo sapiens, clone IMAGE 3606519, mRNA 88
440486 BE243513 Hs 7212 hypothetical protein PP1044 87
445525 BE149866 Hs 14831 Homo sapiens, Similar to zinc finger pro 87
408949 AF189011 Hs 49163 putative πbonuclease III 87
424668 D83702 Hs 151573 cryptocfirome 1 (phololyase-like) 87
412719 AW016610 Hs 129911 ESTε 87
423872 AB020316 Hs 134015 uronyl 2-sulfotransferase 87
408242 AA251594 Hs43913 PIBF1 gene product 87
430848 AW021726 gb df27e02 y1 Morton Fetal Cochlea Homo 87
421492 BE176990 Hε 104916 hypothetical protein FLJ21940 87
449893 T97999 Hε 18214 ESTs, Weakly similar to B34087 hypotheti 87
410442 X73424 Hs 63788 propionyl Coenzyme A carboxylase, beta p 87
425913 AA365799 Hs 50785 SEC22, vesicle trafficking protein (S c 87
425704 U79293 Hs 159264 Human clone 23948 mRNA sequence 87
427723 AI355260 Hs 279789 histone deacetylase 3 87
441683 BE564214 Hs 102946 ESTs 87
447335 BE617695 Hs 286192 hypothetical protein FLJ20940 87
428259 AA424793 Hs 24144 ESTs 87
433104 AL043002 Hs 128246 ESTs, Moderately similar to unnamed prot 87
420041 AB005142 Hs 94592 klotho 87
432432 AA541323 Hs 115831 ESTs 87
452335 AW188944 Hs 61272 ESTε 87
412673 AL042957 Hs 31845 ESTε 87
430335 D80007 Hs 239499 KIAA0185 protein 87
419904 AA974411 Hs 18672 ESTs 86
442402 NM.000954 Hs 8272 prostaglandm D2 synthase (21kD, brain) 86
433759 AA680003 Hs 109363 Homo sapiens cDNA FLJ23603 fis, clone L 86
434064 AL049045 Hs 180758 hypothetical protein PRO0082 86
401785 NM.002275* Homo sapiens keratin 15 (KRT1 86
418407 AL044818 Hs 84928 nuclear transcription factor Y, beta 86
419647 AA348947 Hs 91816 hypothetical protein 86
425907 AA365752 Hs 155965 ESTs 86
452017 AF109302 Hs 27495 prostate cancer assxiated protein 7 86
424434 H87028 Hs 146861 hypothetical protein FLJ20580 86
400303 AA242758 Hs 79136 LIV-1 protem, estrogen regulated 86
414680 AA743331 Hs 272572 hemoglobin, alpha 2 86
413992 W26276 Hs 136075 RNA, U2 small nuclear 86
415071 AK002197 Hs 284270 Homo sapieπε cDNA FLJ 11335 fis, clone PL 86
451230 BE546208 Hs 26090 hypothetical protein FU 20272 86
441790 AW294909 Hs 132208 ESTs 86
441124 T97717 Hs 119563 ESTε 86
438160 AA779332 Hs 122671 ESTε 86
433264 D85782 Hs 3229 cysteine dioxygenase, type I 86
434851 AA806164 Hs 116502 ESTs 86
420608 BE548277 Hs 103104 ESTs 86
426535 AU077012 Hs 288582 ESTs, Weakly similar to ubiquitous TPR m 86
411667 BE160198 gb QV1-HT0413-010200 059 h03 HT0413 Homo 85
454058 AI273419 Hs 135146 hypothetical protem FU 13984 85
435614 R09718 Hs 20403 ESTs 85
446595 T57448 Hs 15467 hypothetical protein FLJ20725 85
435677 AA694142 Hs 293726 ESTs, Weakly similar to TSGA RAT TESTIS 85
447894 AW204253 Hs 21912 ESTs 85
452682 AA456193 Hs 9071 progesterone membrane binding protein 85
418372 AA311833 Hs 84318 replication protein A1 (70kD) 85
447231 AK001293 Hs 330208 crystallin, zeta (qumone reductase) lik 85
416206 AW206248 Hs 111092 hypothetical protein FLJ22332 85 434747 AA837085 Hε 220585 ESTs 85
415938 BE383507 Hs 78921 A kinase (PRKA) anchor protein 1 85
450813 AI739625 Hs 203376 ESTs 85
413956 AI821351 Hs 193133 ESTs, Weakly similar to ALU7.HUMAN ALU S 85
408699 AA056614 Hs 106200 ESTs, Moderately similar to ZN91.HUMAN Z 85
440840 AW629666 Hs 283713 ESTs, Weakly similar to S64054 hypotheti 85
407891 AA486620 Hs 41135 endomucιn-2 85
411019 AW993097 Hs 48617 Homo sapiens cDNA FLJ12540 fis, clone NT 8 5
432620 AA777749 Hs 5978 LIM domain only 7 85 0 424511 BE300512 Hs 193557 ESTs, Moderately similar to ALU7.HUMAN A 85
408170 AW204516 Hs 31835 ESTs 85
452670 AF068227 Hs 30213 ceroid lipofuscmosis, neuronal 5 85
450516 AA902656 Hs 21943 NIF3 (Ngg1 interacting factor 3, S pombe 8 5
417560 U73338 Hs 82283 5-methyltetrahydrofolate homocysteiπe me 8 5 5 430606 BE266026 Hs 31476 Homo sapιeπs cDNA FU13872 fis, clone TH 84
436953 AW959074 Hs 23648 Homo sapιenε cDNA FLJ13097 fis, clone NT 84
418120 AA213437 Hs 192249 ESTs 84
419436 AA991639 Hs 242413 hypothetical protein DKFZp434K1421 84
432600 AI821085 gb ns95a12 y5 NCI_CGAP_Pr3 Homo εapienε 84 0 448474 AI792014 Hs 13809 hypothetical protein FLJ10648 84
434384 AA631910 Hs 162849 ESTε 84
452234 AW084176 Hs 223296 ESTs, Weakly similar to I38022 hypotheti 84
411562 AL050201 Hs 70769 hypothetical protein DKFZp586E1923 84
421622 AB037748 Hs 106204 KIAA1327 protein 84 5 431160 AW971174 Hs 324330 ESTs 84
449567 AI990790 Hs 188614 ESTs 84
411088 BE247593 Hs 145053 ESTs 84
452186 AA120761 Hs 28307 WW domain binding protein 4 (formm bind 83
437872 AK002015 Hs 5887 RNA binding motif protein 7 83 0 429393 AA383024 Hs 201603 Homo εapienε mRNA, cDNA DKFZp434D0917 (f 83
425692 D90041 Hs 155956 N-xetyltransferase 1 (arylamine N acety 8 3
438440 AA807228 Hs 225161 ESTs 8 3
431962 AL049385 Hs 272251 Homo sapiens mRNA, cDNA DKFZp586M1418 (f 83
422295 AF051151 Hs 114408 toll like receptor 5 83 5 440146 AW014231 Hs 90790 Homo sapienε cDNA FU22930 fiε, clone K 8 3
425242 D13635 Hs 155287 KIAA0010 gene product 8 3
432769 AA620814 Hs 144959 ESTε 83
433615 AA732982 Hs 269607 ESTs, Weakly similar to ALU1_HUMAN ALU S 83
427229 AI799751 Hs 5635 ESTs 83 0 446947 AF146747 Hs 232165 polycythemia rubra vera 1 , cell surfxe 83
403149 NM.001450 Homo sapiens four and a half L 83
436679 AI127483 Hs 120451 ESTs, Weakly similar to unnamed protein 83
421991 NM 014918 Hs 110488 KIAA0990 protein 83
436476 AA326108 Hs 33829 bHLH protein DEC2 8 3 5 434980 AW770553 Hs 14553 sterol O xyltranεferaεe (xyl-Coeπzyme 83
407385 AA610150 Hs 272072 ESTε, Weakly similar to I38022 hypotheti 83
453121 AI968264 Hs 232286 ESTs 8 3
420630 AL133101 Hs 99508 Homo sapiens mRNA, cDNA DKFZp434O0921 (f 83
426101 AL049987 Hs 166361 Homo sapiens mRNA, cDNA DKFZp564F112 (fr 82 0 419517 AF052107 Hs 90797 Homo sapienε clone 23620 mRNA sequence 82
425707 AF115402 Hs 11713 E74-lιke fxtor 5 (ets domain transcript 82
440080 AW051597 Hs 143707 ESTε 82
422049 W25760 Hs 77631 glycine cleavage system protein H (ammo 8 2
430154 AW583058 Hs 234726 seπne (or cysteine) proteinase inhibito 82 5 432695 D63480 Hs 278634 KIAA0146 protein 82
407300 AA102616 gb zπ43e07 s1 Stratagene HeLa cell s393 82
408964 AF201468 Hs 49349 beta εite APP-cleaving enzyme 82
418051 AW192535 Hs 19479 ESTε 82
412125 Y17114 Hs 73393 eyeε absent (Drosophila) homolog 4 8 2 0 441523 AW514263 Hs 301771 ESTε, Weakly similarto ALUF.HUMAN mi 8 2
417958 AA767382 Hs 193417 ESTs 82
452040 AW973242 Hs 293690 ESTs, Weakly similar to I38022 hypotheti 82
430468 NM.004673 Hs 241519 angiopoietin-like 1 82
407802 D84145 Hs 39913 novel RGD-containing protein 82 5 420556 AA278300 Hs 124292 Homo sapiens cDNA FU23123 fis, clone L 82
414138 AA135884 Hs 3772 ESTs 82
438209 AL120659 Hs 6111 aryl-hydrocarbon rxeptor nuclear transi 8 2
408267 AW380525 Hs 32675 tubulin specific chaperone e 82
429692 N48422 Hs 9977 ESTs, Weakly similar to B34087 hypotheti 82 0 408108 AI580492 Hs 42743 hypothetical protein 8 2
408418 AW963897 Hs 44743 KIAA1435 protein 8 2
430334 AI824719 Hs 328700 ESTs 82
422083 NM 001141 Hs 111256 arachidonate 15-lιpoxygeπase, sxond typ 82
75
TABLE 59B
Pkey Unique Eoε probeεet identifier number „ Λ CAT number Gene cluster number oO Accession Genbank acceεsion numbers
Pkey CAT Number Accessions
409385 112523.1 AA071267 T65940 T64515AA071334 409752 115301 1 AW963990 AA078196 AW749482 AA077468 BE151571 AA376917
411479 1247077.1 AW848047 AW848202 AW848631 AW848142 AW848702 AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069 AW848905
AW848214
411667 1253334 1 BE160198 AW935898 T11520 AW935930 AW856073 AW861034
416913 163001 1 AW934714 BE161007 BE162500 AW749902 AW749864 BE162498 BE161005 AA190449 AW513465 BE161006 BE162499
418866 179788 1 T65754 AA229857 AA229658
418876 179960 1 AA740616 AA654854 AA229923
419536 185688 1 AA603305 AA244095 AA244183
419544 185760 2 AI909154 AA526337 AA244193 AI909153
423800 232161 1 AA331156 AA331157 AA331155
426413 266650 1 AA377823 AW954494 AI022688
429163 300543 1 AA884766AW974271 AA592975 AA447312
430848 324621 1 AW021726 AA487752 AA488085
431121 328275 1 AW971157 AA492575 AA492520
432189 342819 1 AA527941 AI810608 AI620190 AA635266
432600 350959 1 AI821085 AW973464 AA554802 AI821831 AA657438 AA640756 AA650339
434415 385931 1 BE177494 AW276909 AA632849
434579 38916 1 T55958T57205 AF147346
439518 47334 1 W76326 AF086341 W72300
443161 561305 1 AI038316AI344631 AI261653
447974 745643 1 R76886 AI453674 R77049
TABLE 59C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numberε "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide positions of predicted exonε
Pkey Ref Strand NLposition
400860 9757499 Minus 151830-152104,152649-152744
400880 9931121 Plus 29235-29336,36363-36580
401197 9719705 Plus 176341-176452
401424 8176894 Plus 24223-24428
401519 6649315 Plus 157315-157950
401558 7139678 Plus 103510-104090
401747 9789672 Minus 118596-118816,119119-119244,119609 119761,120422-120990,130161-130381,130468-130593,131097-131258,131866- 131932,132451-132575,133580-134011
401785 7249190 Minus 165776-165996,166189-166314,166408-166569,167112-167268,167387-167469,168634-168942
402076 8117410 Plus 128316-128627
402812 6010110 Plus 25026-25091,25844-25920
402855 9662953 Minus 59763-59909
403047 3540153 Minus 59793-59968
403137 9211494 Minus 92349-92572,92958-93084,93579-9371293949-94072,94591-94748,95214-95337
403149 9799833 Plus 25034-25185
403362 8571772 Plus 64099-64260
404210 5006246 Plus 169926-170121
404571 7249169 Minus 112450-112648
404641 9796810 Minus 32247-32362
404642 9796810 Plus 102999-103145
405523 9454643 Plus 114550-114688,117265-117407,119490-119599,123237-123395,131140-131217
Table 60A lists about 1166 genes up-regulated in prostate cancer compared to normal adult tissues These were selxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" prostate cancer to "average" normal adult tisεueε was greater than or equal to 30 The "average" prostate cancer level was set to the 75"' percenfile amongst prostate cancers The "average" normal adult tisεue level waε εet to the 85"1 percentile amongεt non-malignant tissues In order to remove gene-specific bxkground levels of πon-spxific hybndization, the 10* percentile value amongst the non-malignant tissueε waε εubtrxted from both the numerator and the denominator before the ratio waε evaluated
TABLE 60A ABOUT 1166 GENES UP-REGULATED IN PROSTATE CANCER COMPARED TO NORMAL ADULT TISSUES
Pkey Unique Eoε probeset identifier number
ExAccn Exemplar Accesεion number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of prostate tumor to normal adult body tissue
Pkey ExAccn Unigene ID Unigene Title R1
426747 AA535210 Hs 171995 kallikrein 3, (prostate specific antigen 566
419526 AI821895 Hs 193481 ESTs 562
420154 AI093155 Hε 95420 JM27 protein 440
432441 AW292425 Hε 163484 ESTs 41 9
414569 AF109298 Hs 118258 prostate cancer asεxiated protein 1 399
431616 AA508552 Hs 195839 ESTε, Weakly similar to I38022 hypotheti 379
400299 X07730 Hs 171995 kallikrein 3, (prostate εpxific antigen 360
446057 AI420227 Hs 149358 ESTε, Weakly similar to A46010 X-lmked 329
425075 AA506324 Hs 1852 acid phosphatase, prostate 31 1
400298 AA032279 Hs 61635 six transmembrane epithelial antigen of 300
439176 A1446444 Hs 190394 ESTs, Weakly similar to B28096 lιne-1 pr 298 400302 N48056 folate hydrolase (prostate-specific memb 289
431579 AW971082 Hs 222886 ESTs, Weakly similar to TRHY HUMAN TRICH 279
432101 AI918950 Hs 123642 EphA3 263
408369 R38438 Hs 182575 solute carrier family 15 (H?1?-? transport 262
453096 AW294631 Hs 11325 ESTs 257
400287 S39329 Hs 181350 kallikrein 2 prostatic 255
409262 AKO00631 Hs 52256 hypothetical protein FU20624 246
428819 AL135623 Hs 193914 KIAA0575 gene product 245
401424 NM.001172 Homo sapienε argmase, type II 245
453370 AI470523 Hs 139336 ATP binding cassette, sub family C (CFTR 224
400292 AA250737 Hs 72472 BMP-R1B 223
407202 N58172 Hs 109370 ESTs 223
415989 AI267700 ESTs 202
407709 AA456135 Hε 23023 ESTs 200
407168 R45175 Hs 117183 ESTs 19 6
433444 AW975324 Hs 129816 ESTε 194
409731 AA125985 Hs 56145 thymosm, beta, identified in neuroblast 191
428336 AA503115 Hs 183752 microsemmoproteiπ, beta 187
410929 H47233 Hs 30643 ESTs 18 0
424099 AF071202 Hs 139336 ATP-bindmg casεette, εub family C (CFTR 179
418961 AW967646 Hs 23023 ESTε 177
452792 AB037765 Hs 30652 KIAA1344 protein 175
403047 NM.005656* Homo εapiens transmembrane pr 173
433466 AA508353 Hs 105314 relaxm 1 (H1) 173
418396 AI765805 Hε 26691 ESTs 17 1
433647 AA603367 Hs 222294 ESTs 169
432240 AI694767 Hs 129179 Homo sapiens cDNA FU13581 fis, clone PL 167
430487 D87742 Hs 241552 KIAA0268 protein 16 5
440260 AI972867 Hs 7130 copine IV 16 0
429170 NMJ01394 Hs 2359 dual specificity phosphatase 4 157
429220 AW207206 ESTs 157
416370 N90470 Hs 203697 ESTs, Weakly similar to I38022 hypotheti 153
418819 AA228776 Hs 191721 ESTs 148
421513 X00949 Hε 105314 relaxm 1 (H1) 148
429918 AW873986 Hε 119383 ESTs 145
420092 AA814043 Hs 88045 ESTs 145
432473 AI202703 Hs 152414 ESTs 144
450693 AW450461 Hs 203965 ESTs 144
431548 AI834273 Hs 9711 novel protein 144
432674 AA641092 Hε 257339 ESTs, Weakly similar to 138022 hypotheti 143
430187 AI799909 Hε 158989 ESTs 143
441690 R81733 Hε 33106 ESTs 143
408621 AI970672 Hε 46638 chromosome 11 open reading frame 8 142
448999 AF179274 Hs 22791 transmembrane protein with EGF-like and 137
450642 R39773 Hs 7130 copine IV 135
430376 AW292053 Hs 12532 chromosome 1 open reading frame 21 134
432966 AA650114 Hs 325198 ESTs 134
410330 AW023630 Hs 159425 ESTs 134
434666 AF151103 Hs 112259 T cell rxeptor gamma Ixus 131
400297 AI127076 Hs 306201 hypothetical protein DKFZp56401278 130
423073 BE252922 Hs 123119 MAD (mothers against dxapentaplegic, Dr 128
431474 AL133990 Hs 190642 ESTs 126
418829 AA516531 Hs 55999 NK homeobox (Drosophila), family 3, A 125
453861 AI026838 Hs 30120 ESTs, Weakly similarto NUCL HUMAN NUCLE 125
434217 AW014795 Hs 23349 ESTs 123
418432 M14156 Hs 85112 insulin-like growth fxtor 1 (somatomedi 123
428398 AI249368 Hs 98558 ESTs 12 2
421059 AI654133 Hs 30212 thyroid receptor interxting protein 15 122
447313 U92981 Hs 18081 Homo sapiens clone DT1 P1 B6 mRNA, CAG rep 122
443960 AI093577 Hε 255416 hypothetical protein FLJ21986 121
448290 AK002107 Hε 20843 Homo sapiens cDNA FLJ11245 fis, clone PL 12 1
436032 AA150797 Hs 109276 latexin protein 120
432527 AW975028 Hs 102754 ESTs 120
434792 AA649253 Hs 132458 ESTs 120
420424 AB033036 Hs 97594 KIAA1210 protein 11 9
440529 AW207640 Hs 16478 Homo sapienε cDNA FLJ21718 fis, clone C 11 9
424846 AU077324 Hs 1832 neuropeptide Y 11 9
448519 AW175665 Hε 278695 Homo sapienε prostem mRNA, complete eds 11 9
418339 AA639902 Hε 104215 ESTs, Moderately similar to SPCN.HUMAN S 11 8
432600 AI821085 gb πs95a12 y5 NCI CGAP Pr3 Homo εapiens 11 8
413597 AW302885 Hε 117183 ESTs 11 8
446100 AW967109 Hε 13804 hypothetical protein dJ462023 2 11 7
431448 AL137517 Hs 306201 hypothetical protein DKFZp56401278 11 6
424701 NM.005923 Hs 151988 mitogen-xtivated protein kinase kinase 11 6
432435 BE218886 Hs 282070 ESTs 11 5
429290 AF203032 Hs 198760 neurofilament, heavy polypeptide (200kD) 11 5
410467 AF102546 Hs 63931 dachshund (Drosophila) homolog 11 5
439444 AI277652 Hs 54578 ESTs, Weakly similar to I38022 hypotheti 11 5
450382 AA397658 Hs 60257 Homo εapienε cDNA FLJ13598 fiε, clone PL 11 5
452340 NM.002202 Hs 505 ISL1 transcription factor, LIM/homeodoma 11 1
417332 AW972717 Hs 288462 hypothetical protein FLJ21511 11 0
407021 U52077 gb Human maπnerl tranεposase gene, comp 11 0
419563 AA526235 Hs 193162 Homo sapieπε cDNA FLJ11983 fis, clone HE 10 8 432729 AK000292 Hs 130732 hypothetical protein FLJ20285 106
400301 X03635 Hs 1657 estrogen rxeptor 1 10 5
419536 AA603305 gb πp12d11 s1 NCI_CGAP_Pr3 Homo sapienε 105
445472 AB006631 Hs 12784 Homo εapienε mRNA for KIAA0293 gene par 10 5
415539 AI733881 Hs 72472 BMP R1B 104
419264 AA877104 Hs 293672 ESTε Weakly similar to ALUB.HUMAN "» 104
424432 AB037821 Hs 146858 protxadheπn 10 103
439518 W76326 gb zd60d04 r1 Soares_fetal_heart_NbHH19W 10 3
434036 AI659131 Hs 197733 hypothetical protein MGC2849 10 3
415263 AA948033 Hs 130853 ESTε 102
431217 NM 013427 Hs 250830 Rho GTPase xtivatmg protein 6 10 2
444805 AB007899 Hs 12017 homolog of yeast ubiquitin protein ligas 101
437252 AI433833 Hs 164159 ESTs Weakly similar to ALULHUMAN ALU S 10 1
444190 AI878918 Hs 10526 cysteine and glycine rich protein 2 100
418293 AI224483 Hs 16063 hypothetical protein FLJ21877 100
432244 AI669973 Hs 200574 ESTs 100
451640 AA195601 Hs 26771 Human DNA sequence from clone 747H23 on 99
450164 AI239923 Hs 63931 ESTs 98
447072 D61594 Hs 17279 tyrosylprotein sulfotranεferaεe 1 98
415079 R43179 Hs 22895 hypothetical protein FLJ23548 97
409799 D11928 Hs 76845 phosphoseπne phosphatase like 96
433234 AB040928 Hs 65366 KIAA1495 protein 95
400296 AA305627 Hs 139336 ATP binding cassette sub family C (CFTR 95
422728 AW937826 Hs 103262 ESTs Weakly similar to ZN91_HUMAN ZINC 95
425154 NM.001851 Hs 154850 collagen type IX alpha 1 94
433927 AI557019 Hs 116467 εmall nuclear protein PRAC 94
444670 H58373 Hs 332938 hypothetical protein MGC5370 94
449625 NM 014253 odz (odd Oz/ten m Droεophila) homolog 1 94
450325 AI935962 Hs 26289 ESTε 94
427761 AA412205 Hs 140996 ESTε 94
453930 AA419466 Hs 36727 hypothetical protein FLJ 10903 94
416795 AI497778 Hs 20509 HBV pX aεεxiated protein 8 93
422805 AA436989 Hs 121017 H2A histone family member A 93
418848 AI820961 Hs 193465 ESTε 92
408430 S79876 Hs 44926 dipeptidylpeptidase IV (CD26 adenosme 92
415788 AW628686 Hs 78851 KIAA0217 protein 92
404641 NM 021965* Homo sapienε phosphoglucomuta 91
432437 W07088 Hs 293685 ESTε 9 1
436396 AI683487 Hs 152213 wingless type MMTV integration site fami 91
436962 AW377314 Hs 5364 DKFZP564I052 protein 91
410765 AI694972 Hs 66180 nucleosome aεsembly protein 1 like 2 90
428342 AI739168 Homo sapiens cDNA FLJ13458 fis clone PL 90
452281 T93500 Hs 28792 Homo sapiens cDNA FLJ11041 fis clone PL 90
433043 W57554 Hs 125019 lymphoid nuclear protein (LAF 4) mRNA 88
442082 R41823 Hs 7413 ESTs 88
436671 AW137159 Hs 146151 ESTs 87
415786 AW419196 Hs 257924 hypothetical protein FU 13782 87
440774 AI420611 Hs 153934 ESTs 87
420120 AL049610 Hs 95243 transcnption elongation fxtor A (Sll) 87
427138 N77624 Hs 173717 phosphatidic xid phosphatase type 2B 87
430722 AW968543 Hs 203270 ESTs Weakly similar to ALU1.HUMAN ALU S 86
422487 AJ010901 Hs 198267 mucin 4 trxheobranchial 86
443646 AI085198 Hs 164226 ESTs 86
414565 AA502972 Hε 183390 hypothetical protein FLJ13590 85
428728 NM 016625 Hs 191381 hypothetical protem 85
434926 BE543269 Hs 50252 mitxhondπal πbosomal protein L32 85
437162 AW005505 Hs 5464 thyroid hormone rxeptor coxtivating pr 85
437866 AA156781 metallothionein 1E (functional) 85
453006 AI362575 Hs 303171 ESTs 84
418723 AA504428 Hs 10487 Homo sapiens clone IMAGE 3954132 mRNA 83
421040 AA715026 Hs 135280 ESTs 83
414212 AA136569 Hs 10848 KIAA0187 gene product 83
417916 NM 006416 Hs 82921 solute earner family 35 (CMP sialic xi 82
440749 W22335 Hs 7392 hypothetical protein MGC3199 82
412715 NM.000947 Hs 74519 pnmase polypeptide 2A (58kD) 82
428829 R14050 Hs 194051 Homo sapiens mRNA cDNA DKFZp566B213 (fr 82
447156 AW274731 Hs 157920 ESTs 8 1
428330 L22524 Hs 2256 matnx metalloprotemase 7 (matπlysm 8 1
417412 X16896 Hs 82112 interleukin 1 rxeptor type I 80
424692 AA429834 Hs 151791 KIAA0092 gene product 80
435981 H74319 Hs 188620 ESTs 79
442081 AA401863 Hs 22380 ESTs 79
434988 AI418055 Hs 161160 ESTs 79
407910 AA650274 Hs 41296 fibronectin leucine πch tranεmembraπe p 78
420345 AW295230 Hs 25231 ESTε 78
412324 AW978439 Hε 69504 ESTs 78
420757 X78592 Hε 99915 androgen receptor (dihydrotestosterone r 78
408374 AW025430 Hε 155591 forkhead box F1 78
435604 AA625279 Hs 26892 uncharxteπzed bone marrow protein BM04 78
453160 AI263307 Hs 239884 H2B histone family member L 78
424051 AL110203 Hs 138411 Homo sapienε mRNA cDNA DKFZp586J1922 (f 77
416182 NM 004354 Hs 79069 cyclin G2 77
452110 T47667 Hs 28005 Homo εapieπε cDNA FLJ11309 fis clone PL 76 451099 R52795 Hs 25954 interleukin 13 receptor, alpha 2 76
427003 U19487 Hs 2090 prostaglandiπ E receptor 2 (εubtype EP2) 75
443180 R15875 Hs 258576 claudin 12 75
454119 BE549773 Hs 40510 uncoupling protein 4 75
418693 AI750878 Hs 87409 thrombospondm 1 75
426581 AB040956 Hs 135890 KIAA1523 protein 75
417683 AW566008 Hs 239154 ankyπn repeat family A (RFXANK like), 75
439569 AW602166 Hs 222399 CEGP1 protein 74
416140 AI918035 Hs 301198 roundabout (axon guidance receptor, Dros 74
451230 BE546208 Hs 26090 hypothetical protein FLJ20272 74
400294 N95796 Hs 278695 Homo εapiens prostem mRNA complete eds 74
436873 N23874 Hs 50477 RAB27A member RAS oncogene family 74
419743 AW408762 Hs 5957 Homo sapiens clone 24416 mRNA sequence 73
428600 AW863261 Hs 242413 hypothetical protein DKFZp434K1421 73
410252 AW821182 Hs 61418 microfibπllar assxiated protein 1 73
424649 BE242035 Hs 151461 embryonic ectoderm development 73
428218 AA424266 Hs 123642 EphA3 73
434158 T86534 Hs 14372 ESTs 73
413249 AF167160 Hs 75251 DEAD/H (Asp Glu Ala Asp/His) box binding 73
430261 AA305127 Hs 237225 hypothetical protein HT023 73
429597 NM 003816 Hs 2442 a disintegnn and metalloprote ase doma 73
423566 AW976434 Hε 3623 hypothetical protein FU11220 72
433556 W56321 Hs 111460 calcium/calmodulm dependent protein km 72
420871 AA702972 Hs 65300 ESTs 72
418278 AI088489 Hs 83937 hypothetical protein 7 1
456516 BE172704 Hs 222746 KIAA1610 protein 7 1
417511 AL049176 Hs 82223 chordin like 71
411667 BE160198 gb QV1-HT0413 010200 059 h03 HT0413 Homo 7 1
414422 AA147224 Hs 249195 Homx box A13 71
407118 AA156790 Hs 262036 ESTs, Weakly similar to Z223.HUMAN ZINC 7 1
421566 NM.000399 Hs 1395 early growth response 2 (Krox-20 (Drosop 70
418564 AA631143 Hs 278695 Homo εapienε proεtem mRNA, complete eds 70
437872 AK002015 Hs 5887 RNA binding motif protein 7 70
448148 NM 016578 Hs 20509 HBV pX asεociated protein 8 70
449523 NM 000579 Hs 54443 chemokine (C-C motif) receptor 5 69
431657 AI345227 Hs 105448 ESTs, Weakly similar to B34087 hypotheti 69
457728 AW974811 gb EST386916 MAGE resequences, MAGN Homo 69
415910 U20350 Hs 78913 chemokine (C-X3 C) rxeptor 1 69
421977 W94197 Hs 110165 nbosomal protein L26 homolog 69
432161 AK000400 Hs 341181 ESTs, Weakly similar to envelope [H sapi 69
432887 AI926047 Hs 162859 ESTε 68
444931 AV652066 Hs 75113 general transcnption fxtor IIIA 68
421823 N40850 Hs 28625 ESTs 68
426981 AL044675 Hs 173081 KIAA0530 protein 68
425170 AU077315 Hs 154970 transcnption factor CP2 68
411479 AW848047 gb IL3-CT0214-291299 052 A12 CT0214 Homo 68
420954 AA282074 Hs 237323 N acetylglucosamine phoεphate mutase 68
439492 AF086310 Hs 103159 ESTs 68
449919 AI674685 Hs 200141 ESTs 68
452221 C21322 Hs 288057 hypothetical protein FLJ22242 68
431555 AI815470 Hs 260024 Cdc42 effector protein 3 67
441111 AI806867 Hs 126594 ESTs 67
457498 AI732230 Hs 191737 ESTs 67
415293 R49462 Hs 106541 ESTs 67
429163 AA884766 gb am20a10 s1 Soareε NFL.T GBC SI Homo ε 67
433908 AW298141 Hs 157975 ESTs 67
446896 T15767 Hs 22452 Homo sapienε mRNA for KIAA1737 protein, 67
431770 BE221880 Hs 268555 5'-3' exoπbonuclease 2 67
418575 AA225313 Hs 222886 ESTs, Weakly similar to TRHY.HUMAN TRICH 66
443745 AB039670 Hs 9728 ALEX1 protein 66
427958 AA418000 Hs 98280 potassium intermediate/εmall conductance 66
447805 AW627932 Hs 302421 gemιπ4 66
440995 T57773 Hs 10263 ESTε 66
422173 BE385828 Hs 250619 phorbolm like protein MDS019 66
431992 NM 002742 Hs 2891 protein kinase C, mu 66
437052 AA861697 Hs 120591 ESTs 66
444030 AW021254 Hs 135055 ESTs 66
416836 D54745 Hs 80247 cholxystokin 66
447033 AI357412 Hs 157601 ESTs 65
428927 AA441837 Hs 90250 ESTε 65
432189 AA527941 gb πh30c04 s1 NCI CGAP Pr3 Homo sapienε 65
448779 BE042877 Hs 177135 ESTs 64
430598 AK001764 Hs 247112 hypothetical protein FLJ 10902 64
411630 U42349 Hs 71119 Putative prostate cancer tumor suppresso 64
432682 AI376400 Hs 159588 ESTs 64
441499 AW298235 Hs 101689 ESTs 64
441676 BE564206 Hs 49889 ESTs 64
421077 AK000061 Hs 101590 hypothetical protein 64
452784 BE463857 Hε 151258 hypothetical protein FU21062 64
452055 AI377431 Hε 141693 hypothetical protein MGC10858 64
431576 M76665 Hs 275215 hydroxysteroid (11 beta) dehydrogenase 1 63
418994 AA296520 Hs 89546 selectin E (endothelial adhesion molecul 63
452277 AL049013 Hs 28783 KIAA1223 protein 63 412953 Z45794 Hs 238809 ESTs 63
441247 AW118681 Hε 128051 Homo sapiens thymic stromal lymphopoieti 63
453390 AA862496 Hs 28482 ESTs 63
418450 R84397 Hs 193651 ESTs, Weakly similar to alternatively sp 63
407829 AA045084 Hs 29725 hypothetical protein FLJ13197 63
425704 U79293 Hs 159264 Human clone 23948 mRNA sequence 63
433610 AA806822 Hs 112547 ESTs 63
448552 AW973653 Hs 20104 hypothetical protein FLJ00052 63
412977 AA125910 Hs 191461 ESTs 63
441217 A1922183 Hs 213246 ESTs 63
443912 R37257 Hs 184780 ESTs 63
429281 AA830856 Hs 29808 Homo εapienε cDNA FLJ21122 fis, clone C 62
435021 AA922192 Hs 54709 ESTs 62
425465 L18964 Hs 1904 protein kmase C iota 62
418821 AA436002 Hs 183161 ESTs 62
424511 BE300512 Hs 193557 ESTs, Moderately similar to ALU7 HUMAN A 62
448106 AI800470 Hs 171941 ESTs 62
408418 AW963897 Hs 44743 KIAA1435 protein 62
450728 AW162923 Hs 25363 presemlm 2 (Alzheimer diεeaεe 4) 62
427078 AI676062 Hs 111902 ESTs 62
426931 NM 003416 Hs 2076 zinc finger protein 7 (KOX 4, clone HF 1 62
449907 AA004825 Hs 103281 ESTs 61
458509 AA654650 Hs 282906 ESTs 61
437323 AA371145 Hs 194397 leptm rxeptor 6 1
407902 AL117474 Hs 41181 Homo sapienε mRNA, cDNA DKFZp727C191 (fr 6 1
429302 AU076674 Hs 198899 eukaryotic translation initiation fxtor 61
412673 AL042957 Hs 31845 ESTs 60
410150 AW382942 Hs 260024 ESTs 60
421863 AI952677 Hs 108972 Homo sapiens mRNA, cDNA DKFZp434P228 (fr 60
446947 AF146747 Hs 232165 polycythemia rubra vera 1, cell surface 60
408968 AI652236 Hs 49376 hypothetical protein FLJ20644 60
409047 AW961434 Hs 31539 ESTs 60
418601 AA279490 Hs 86368 calmegin 60
425710 AF030880 Hs 159275 solute earner family, member 4 60
439820 AL360204 Hs 283853 Homo εapiens mRNA full length insert cDN 60
414905 H40873 Hε 175971 ESTs 60
450295 AI766732 Hε 210628 ESTε 60
412505 AA974491 Hs 21734 ESTε 60
428730 AA625947 Hs 25750 ESTε 60
445413 AA151342 Hs 12677 CGI-147 protein 60
451424 AI862026 Hs 302810 Novel human gene mapping to chomosome 20 59
425628 NM 004476 Hs 1915 folate hydrolase (prostate-εpxific memb 59
435677 AA694142 Hs 293726 ESTε, Weakly similar to TSGA RAT TESTIS 59
431359 AW993522 Hs 292934 ESTs 59
404632 NM.022490 Homo sapienε hypothetical prot 59
423748 AI149048 Hs 30211 hypothetical protein FU22313 59
449118 R67477 Hs 23103 Bed (S cerevisiae) homolog 59
405523 C8001409*gι|7441226|pιrl|S31212 collage 59
448807 AI571940 Hs 7549 ESTs 58
404642 NM 021965* Homo sapiens phosphoglucomuta 58
452598 AI831594 ESTs, Weakly similar to ALU7 HUMAN ALU S 58
427212 AW293849 Hs 58279 ESTs, Weakly similarto ALU7.HUMAN ALU S 58
435047 AA454985 Hs 54973 cadheπn-like protein VR20 58
408622 AA056060 Hs 202577 Homo sapienε cDNA FLJ 12166 fiε, clone MA 58
419038 AW134924 Hε 190325 ESTε 58
416913 AW934714 gb RC1-DT0001-031299-011-a11 DT0001 Homo 57
432432 AA541323 Hε 115831 ESTε 57
435937 AA830893 Hε 119769 ESTε 57
414528 AA148950 Hε 188836 ESTε 57
432712 AB016247 Hs 288031 εterol-C5-desaturase (fungal ERG3, delta 57
412783 BE276738 Hs 74578 DEAD/H (Asp-Glu-Ala-Asp/His) box polypep 57
408826 AF216077 Hs 48376 Homo εapiens clone HB-2 mRNA sequence 57
419083 AI479560 Hs 98613 Homo sapienε cDNA FLJ12292 fis, clone MA 57
420184 AA188408 Hs 95665 hypothetical protem 57
428493 AK001745 Hs 184628 hypothetical protein FU 10883 57
443250 AI041530 Hs 132107 ESTs 57
443324 R44013 Hs 164225 ESTs 57
448164 R61680 Hs 26904 ESTs, Moderately similar to Z195 HUMAN Z 57
448172 N75276 Hs 135904 ESTs 57
433332 AI367347 Hs 44898 Homo sapiens clone TCCCTA00151 mRNA sequ 56
453455 AA063553 Hs 221931 ESTs, Weakly similar to JC1087 RNA helic 56
452242 R50956 Hs 159993 gycosyltransferase 56
410141 R07775 Hs 287657 Homo εapienε cDNA FLJ21291 fiε, clone C 56
418019 R68911 Hs 176275 ESTε 56
450813 AI739625 Hs 203376 ESTε 56
419239 AA468183 Hs 184598 Homo εapienε cDNA FU23241 fis, clone C 56
411096 U80034 Hs 68583 mitochondnal intermediate peptidase 56
451684 AF216751 Hs 26813 CDA14 56
427674 NM 003528 I Hs 2178 H2B histone family, member Q 56
407275 AI364186 gb qw34h07 x1 NCI CGAP Ut4 Homo sapiens 56
417958 AA767382 Hs 193417 ESTs 56
418407 AL044818 Hs 84928 nuclear transcription factor Y, beta 56
435176 AA744875 Hs 189413 ESTs 55 428465 AW970976 Hs 293653 ESTs 55
431316 AA502663 Hs 145037 ESTs 55
434804 AA649530 Hs 348148 gb πs44f05 s1 NCI CGAP Alvl Homo εapienε 55
411990 AW963624 Hs 31707 ESTε, Weakly similar to YEW4.YEAST HYPOT 55
416653 AA768553 Hs 193145 metallothioπein 1E (functional) 55
427359 AW020782 Hs 79881 Homo sapienε cDNA FLJ23006 fis, clone L 55
432169 Y00971 Hs 2910 phosphoπbosyl pyrophosphate εynthetase 55
416239 AL038450 Hs 48948 ESTε 54
421470 R27496 Hs 1378 annexm A3 54
408177 AI241733 Hs 43871 ESTε 54
424084 AI940675 Hs 20914 hypothetical protein FLJ23056 54
414171 AA360328 Hs 865 RAP1 A, member of RAS oncogene family 54
448072 AI459306 Hs 24908 ESTs 54
420397 NM 007018 Hs 97437 centrosomal protein 1 54
429250 H56585 Hs 198308 tryptophan πch basic protein 54
453070 AK001465 Hs 31575 SEC63, endoplasmic reticulum tranεlxon 54
429165 AW009886 Hs 118258 prostate cancer assxiated protein 1 54
418866 T65754 gb yd 1c07 s1 Stratagene lung (937210) H 54
428364 AA426565 Hs 311103 ESTε, Moderately similar to ALU1.HUMAN A 54
431467 N71831 Hs 256398 Homo εapiens mRNA, cDNA DKFZp434E0528 (f 54
436679 AI127483 Hs 120451 ESTs, Weakly similar to unnamed protein 54
447188 H65423 Hs 17631 hypothetical protein DKFZp434E2135 54
457211 AW972565 Hs 32399 ESTε, Weakly similar to S51797 vasodilat 53
412677 AW029608 Hs 17384 ESTε 53
430412 AW341754 Hε 189305 ESTε 53
423250 BE061916 Hs 125849 chromosome 8 open reading frame 2 53
421433 AI829192 Hs 22380 ESTs 53
435572 AW975339 Hs 239828 ESTs, Weakly similar to GAG2.HUMAN RETRO 53
458571 AV653731 Hs 282829 ESTs, Moderately similar to PC4259 fern 53
441054 AA913591 Hs 126480 ESTs 53
431725 X65724 Hs 2839 Nome disease (pseudoglioma) 53
433409 AI278802 Hs 25661 ESTs 53
441102 AA973905 intermediate filament protein syncoilm 53
453387 AI990741 Hs 252809 ESTε 53
421928 AF013758 Hs 109643 polyadenylate binding protein mteractiπ 53
433923 AI823453 Hs 146625 ESTε 53
426503 AA380153 gb EST93093 Skin tumor I Homo εapiens cD 52
447574 AF162666 Hs 18895 tousled like kinase 1 52
421896 N62293 Hs 45107 ESTs 52
410870 U81599 Hs 66731 homx box B13 52
420729 AW964897 Hs 290825 ESTs 52
425066 M82882 Hs 154365 E74-lιke factor 1 (els domain transcπpt 52
429467 NM 004477 Hs 203772 FSHD region gene 1 52
447816 NM 007233 Hs 274329 TP53 target gene 1 52
446553 AB021179 Hs 15299 HMBA-mducible 52
453308 AW959731 Hs 323099 ESTs 52
452576 AB023177 Hs 29900 KIAA0960 protein 52
421437 AW821252 Hs 104336 hypothetical protein 52
422295 AF051151 Hs 114408 toll like rxeptor 5 52
453942 AW190920 Hs 19928 hypothetical protein SP329 52
400424 AJ276316 Hs 287374 zinc finger protein 304 52
430387 AW372884 Hs 240770 nuelearcap binding protein subunit 2, 2 52
452588 AA889120 Hs 110637 homx box A10 52
448944 AB014605 Hs 22599 atrophιn-1 interxting protein 1, xtivi 51
413991 H44725 Hs 176090 ESTε 51
444454 BE018316 Hs 11183 sorting nexm 2 51
446795 AI797713 Hs 156471 ESTs 51
407300 AA102616 Hs 120769 gb zπ43e07 s1 Stratageπe HeLa cell s393 51
432340 AA534222 gb nj21d02 s1 NCI_CGAP_AA1 Homo εapienε 51
446469 BE094848 Hs 15113 homogeπtiεate 1,2-dιoxygenase (homogenti 51
453293 AA382267 Hs 10653 ESTs 5 1
408920 AL120071 Hs 48998 fibronxtiπ leucine πch transmembrane p 51
409643 AW450866 Hs 257359 ESTs 5 1
427723 AI355260 Hs 279789 histone dexetylase 3 51
438157 AW137011 Hs 49576 ESTs 5 1
420344 BE463721 Hs 97101 putative G protein-coupled receptor 51
432251 AW972983 Hs 232165 polycythemia rubra vera 1, cell surfxe 5 1
418051 AW192535 Hs 19479 ESTs 51
419926 AW900992 Hs 93796 DKFZP586D2223 protein 5 1
425843 BE313280 Hs 159627 death assxiated protein 3 51
440594 AW445167 Hs 126036 ESTs 51
452449 AW068658 Hs 20943 ESTs 5 1
429769 NMJ04917 Hs 218366 kallikrein 4 (prostase, enamel matnx, p 51
428898 AB033070 Hs 194408 KIAA1244 protein 5 1
415339 NM.015156 Hs 78398 KIAA0071 protein 51
450671 AI356967 Hs 43086 ESTs, Weakly similar to A46010 X-lmked 51
444484 AK002126 Hs 11260 hypothetical protein FLJ11264 50
433023 AW864793 Hs 87409 thrombospondm 1 50
433862 D86960 Hs 3610 KIAA0205 gene product 50
451244 AW008798 Hs 343877 hypothetical protein FLJ20039 50
418624 AI734080 Hs 104211 ESTs 50
430291 AV660345 Hs 238126 CGI 49 protein 50
432261 R42216 Hs 12342 Homo sapienε clone 24538 mRNA εequence 50 429922 Z97630 Hs 226117 H1 histone family, member 0 50
420218 AW958037 Hs 286 nbosomal protein L4 50
425242 D13635 Hs 155287 KIAA0010 gene product 50
427176 AW381569 Hs 40334 ESTs 50
431585 BE242803 Hs 262823 hypothetical protein FLJ10326 50
439699 AF086534 Hs 187561 ESTs, Moderately similar to ALU1_HUMAN A 50
412350 AI659306 Hs 73826 protein tyrosine phosphatase, non-rxept 50
450244 AA007534 Hs 125062 ESTs 50
439731 AI953135 Hs 45140 hypothetical protein FLJ14084 50
434237 AF119908 Hs 235516 hypothetical protein PR02955 50
418700 AI963808 Hs 86970 ESTs, Moderately similar to ALU5.HUMAN A 50
445866 H20899 Hs 13399 Homo sapiens clone 25032 mRNA sequence 49
408331 NM 007240 Hs 44229 dual specificity phosphatase 12 49
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 49
431325 AW026751 Hs 5794 ESTs, Weakly similar to 2109260A B cell 49
444151 AW972917 Hs 128749 alpha-methylxyl-CoA racemase 49
401451 NM.004496* Homo sapienε hepatxyte nude 49
416434 AW163045 Hs 79334 nuclear factor, interleukin 3 regulated 49
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet-ac 49
442281 N34742 Hs 170065 Homo sapienε cDNA FLJ13492 tiε, clone PL 49
420608 BE548277 Hs 103104 ESTε 49
420911 U77413 Hs 100293 O-Iinked N-acetylglucoεamine (GlcNAc) tr 49
424332 AA338919 Hs 101615 ESTε 49
430523 AW451385 Hs 161954 ESTε 49
449300 AI656959 Hs 346514 ESTε 49
426657 NM 015865 Hs 171731 εolute carrier family 14 (urea transport 49
422299 AK000181 Hs 114556 hypothetical protein FLJ20174 49
438321 AA576635 Hs 6153 CGI-48 protein 49
452744 AI267652 Hs 246107 Homo sapiens mRNA, cDNA DKFZp434E082 (fr 49
418818 AA228899 Hs 101307 Homo sapiens HUT11 protein mRNA, partial 48
425174 D87450 Hs 154978 KIAA0261 protein 48
430458 AA479300 Hε 225706 ESTs, Weakly similar to I38022 hypotheti 48
455497 AA112573 Hs 278695 Homo sapienε prostem mRNA, complete eds 48
416208 AW291168 Hs 41295 ESTs, Weakly similar to MUC2 HUMAN MUCIN 48
449539 W80363 Hs 58446 ESTs 48
450654 AJ245587 Hs 25275 Kruppel-type zinc finger protein 48
434228 Z42047 Hs 283978 Homo sapienε PR02751 mRNA, complete cdε 48
407385 AA610150 Hs 272072 ESTs, Weakly similar to I38022 hypotheti 48
420210 AI557257 Hs 44811 ESTs 48
425905 AB032959 Hs 318584 novel C3HC4 type Zinc finger (nng finge 48
428647 AA830050 Hs 124344 ESTs 48
434015 AA844518 Hs 300876 hypothetical protein FU13386 48
441879 AI521936 Hs 107149 novel protein similar to archaeal, yeast 48
408990 AL022395 Hs 49526 f-box and leucine-πch repeat protein 4 48
416030 H15261 Hs 21948 ESTs 48
420948 AB016898 Hs 100469 myeloid/lymphoid or mixed-lineage leukem 48
423749 U09848 Hs 132390 zinc finger protein 36 (KOX 18) 48
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of 47
452323 W44356 Hs 292812 ESTs, Weakly similar to T33468 hypotheti 47
443684 AI681307 Hε 55098 ESTs 47
415621 AI648602 Hs 55468 ESTs 47
420851 AA281062 Hs 29493 hypothetical protein FLJ20142 47
424433 H04607 Hs 9218 ESTs 47
436703 AW880614 Hs 146381 RNA binding motif protein, X chromosome 47
451806 NM.003729 Hs 27076 RNA 3'-termιnal phosphate cyclase 47
433293 AF007835 Hs 32417 hypothetical protein MGC4309 47
434973 AW449285 Hs 313636 EST 47
433560 AI925195 Hs 130891 hypothetical protein MGC4400 47
431687 NM_016179 Hs 262960 transient rxeptor potential channel 4 47
452260 AA453208 RAB9, member RAS oncogene family 47
412846 AW961245 Hs 55896 Homo εapienε PAC clone RP5-978E18 from 7 47
418836 AI655499 Hs 161712 ESTε 47
401558 ENSP00000220478* SECRETOGRANIN III 47
441647 AA534210 Hs 285280 Homo εapienε cDNA FLJ22096 fis, clone H 47
443881 R64512 Hs 237146 hypothetical protein FLJ 12752 47
417169 R13550 Hs 246773 ESTs 47
423349 AF010258 Hs 127428 homeo box A9 47
458611 AI268407 Hs 211458 DC-εpecific tranεmembrane protein 47
444951 AI783767 Hs 148635 ESTε, Moderately similar to ALUB.HUMAN i 46
416774 AI005169 Hs 28274 Homo sapienε cDNA FLJ22049 fis, clone H 46
419465 AW500239 Hs 21187 Homo sapienε cDNA FU23068 fiε, clone L 46
423242 AL039402 Hs 125783 DEME-6 protein 46
452627 AI122843 Hs 184319 ESTε, Weakly similar to KIAA1006 protein 46
419005 T86358 Hs 193931 ESTs, Weakly similar to I54374 gene NF2 46
403046 NM_005656* Homo sapienε tranεmembrane pr 46
416602 NM 006159 Hs 79389 nel (chιckeπ)-lιke 2 46
407426 AF129533 gb Homo εapiens F-box protein Fbl3b (FBL 46
426011 AW996096 Hs 58924 ESTs, Weakly similar to JC5594 jerky gen 46
442138 AA445973 Hs 13303 Homo sapienε cDNA FLJ21784 fis, clone H 46
446015 T30968 Hs 13531 hypothetical protein FLJ10971 46
452994 AW962597 Hs 31305 KIAA1547 protein 46
446091 AW022192 Hs 200197 ESTs 46
432908 AI861896 Hs 304505 ESTs 46 430226 BE245562 Hs 2551 adrenergic, beta 2-, receptor, surface 46
431673 AW971302 Hs 293233 ESTs 46
446183 AA354991 Hs 14222 Homo sapienε mRNA, cDNA DKFZp761P019 (fr 46
452355 N54926 Hs 29202 G protein coupled receptor 34 46
432093 H28383 gb yl52c03 r1 Soares breast 3NbHBst Homo 46
448402 BE244226 Hs 21094 RAB18, member RAS oncogene family 46
409019 AW385412 Hs 9615 myosin regulatory light chain 2 smooth 46
413812 AW188687 Hs 44748 ESTs 46
414343 AL036166 Hs 323378 coated vesicle membrane protein 46
434423 NM.006769 Hs 3844 LIM domain only 4 45
407355 AA846203 Hs 193974 ESTs, Weakly similar to ALU1 HUMAN ALU S 45
421724 AB037832 Hs 107287 KIAA1411 protein 45
412125 Y17114 Hs 73393 eyes absent (Drosophila) homolog 4 45
437330 AL353944 Hs 50115 Homo sapienε mRNA, cDNA DKFZp761J1112 (f 45
446720 AI439136 Hs 140546 ESTs 45
448664 AI879317 Hs 334691 splicing factor 3a, subunit 1, 120kD 45
415083 AI632683 Hs 27179 Homo sapiens cDNA FLJ 12933 fis, clone NT 45
423412 AF109300 prostate cancer associated protein 5 45
433507 AI817336 Hs 191791 ESTs 45
428966 AF059214 Hs 194687 cholesterol 25 hydroxylase 45
423782 AI472209 Hs 323117 ESTs 45
456362 AW973003 Hs 179909 hypothetical protein FLJ22995 45
415451 H19415 Hs 268720 ESTs, Moderately similar to ALU1.HUMAN A 45
419745 AF042001 Hε 93005 slug (chicken homolog), zinc finger prot 45
428715 AW293716 Hs 53126 ESTε 45
429857 AF089897 Hs 294030 topoisomerase related function protein 4 45
459561 AI547306 ESTs 45
416155 AI807264 Hs 205442 ESTs Weakly similar to T34036 hypotheti 45
414272 A1651603 Hs 46988 ESTs 45
424690 BE538356 Hs 151777 eukaryotic translation initiation fxtor 45
417350 U50928 Hs 82001 polycystic kidney diεeaεe 2 (autoεo al d 45
450094 AI174947 Hs 295789 Homo εapiens mRNA, cDNA DKFZp564D1164 (f 45
459324 AW080953 gb xc28c12 x1 NCI_CGAP_Co18 Homo sapiens 45
429784 M89796 Hs 30 membrane-spanning 4-domams, subfamily A 45
401519 C15000476* gι|12737279|ref|XP_012163 1| 45
417576 AA339449 Hε 82285 phosphoπboεylglycinamide formyltranεfer 45
427484 N32859 Hε 37288 nuclear receptor subfamily 1 , group D, m 45
417061 AI675944 Hε 188691 Homo sapienε cDNA FLJ12033 fiε, clone HE 44
418858 AW961605 Hε 21145 hypothetical protein RG083M052 44
433517 AW022133 Hs 189838 ESTε 44
429559 AI985345 Hs 26425 ESTε 44
452338 AW608920 Hs 29159 zinc finger protein 75 (D8C6) 44
409190 AU076536 Hs 50984 εarcoma amplified sequence 44
444922 AI921750 Hs 144871 Homo sapienε cDNA FU 13752 fiε, clone PL 44
416547 H62914 Hs 268946 ESTs, Weakly similar to PC4259 femtin 44
430320 BE245290 Hs 239218 uπcharacteπzed hypothalamus protein HCD 44
436953 AW959074 Hs 23648 Homo sapienε cDNA FLJ 13097 fis, clone NT 44
438497 AA808725 Hs 291712 ESTs, Weakly similar to I38022 hypotheti 44
434384 AA631910 Hs 162849 ESTs 44
444564 AI167877 Hs 143716 ESTs 44
447500 AI381900 Hs 159212 ESTs 44
425259 AL049280 Hs 155397 Homo sapienε mRNA, cDNA DKFZp564K143 (fr 44
408380 AF123050 Hs 44532 diubiquibn 44
448766 AI473827 Hs 31793 ESTs 44
417421 AL138201 Hs 82120 nuclear rxeptor subfamily 4, group A, m 44
432810 AA863400 ESTs 44
437812 AI582291 Hs 16846 ESTs, Weakly similar to 04HUD1 debπsoqu 44
447247 AW369351 Hs 287955 Homo sapiens cDNA FU 13090 fis, clone NT 44
434022 R18374 Hs 117956 ESTs 44
422365 AF035537 Hs 115521 REV3 (yeast homolog)-lιke, catalytic sub 44
417728 AW138437 Hs 24790 KIAA1573 protein 44
420407 AA814732 Hs 145010 lipopolysxcande-εpxific reεponεe 5-lι 44
425810 AI923627 Hs 31903 ESTε 44
432882 NM 013257 Hs 279696 εerum/glucxorticoid regulated kinase-li 43
448550 AL161983 Hs 21415 Homo sapiens mRNA, cDNA DKFZp761K2024 (f 43
410227 AB009284 Hs 61152 exostoseε (multιple)-lιke 2 43
417845 AL117461 Hs 82719 Homo εapiens mRNA, cDNA DKFZp586F1822 (f 43
452335 AW188944 Hs 61272 ESTs 43
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 43
450316 W84446 Hs 226434 hypothetical protein MGC4643 43
408527 AL135018 Hs 33074 Homo sapienε, clone IMAGE 3606519, mRNA, 43
419852 AW503756 Hs 286184 hypothetical protein dJ551D25 43
424534 D87682 Hs 150275 KIAA0241 protein 43
424850 AA151057 Hs 153498 chromoεome 18 open reading frame 1 43
435023 AI692552 gb wd73f12 x1 NCI_CGAP_Lu24 Homo εapienε 43
442914 AW188551 Hs 99519 hypothetical protein FLJ14007 43
452679 Z42387 Hs 83883 transmembrane, proεtate androgen induced 43
421163 AA375974 Hs 32450 ESTε, Weakly similar to T23762 hypotheti 43
420405 AA743396 Hs 189023 ESTs 43
450330 AW500775 Hε 24817 hypothetical protein FLJ20136 43
423998 H29138 Hs 157113 coenzyme Q, 7 (rat, yeast) homolog 43
439764 T26535 Hs 22744 hypothetical protein MGC13105 43
446351 AW444551 Hs 35380 x 001 protein 43 431583 AL042613 Hs 262476 S adenosylmethionme decarboxylase 1 43
414312 AA155694 Hs 191060 ESTs 43
438379 N23018 Hs 171391 C-terminal binding protein 2 43
411928 AA888624 Hs 197289 rab3 GTPase-activating protem noπ-cata 43
414680 AA743331 hemoglobin, alpha 2 43
423104 AJ005273 Hs 123647 antigenic determinant of recA protein (m 43
440840 AW629666 ESTs, Weakly similar to S64054 hypotheti 43
449802 AW901804 Hs 23984 hypothetical protein FLJ20147 43
434874 N62448 Hs 293970 methylmalonate semialdehyde dehydrogenas 42
431429 AF072813 reticulon 3 42
413492 D87470 Hs 75400 KIAA0280 protein 42
419929 U90268 Hs 93810 cerebral cavernouε malformations 1 42
435846 AA700870 Hs 14304 ESTs 42
441523 AW514263 Hs 301771 ESTε, Weakly similar to ALUF HUMAN "» 42
450546 AA010200 Hs 175551 ESTs 42
414222 AL135173 Hs 878 sorbitol dehydrogenase 42
416445 AL043004 Hs 79337 KIAA0135 protein 42
409151 AA306105 Hs 50785 SEC22, vesicle trafficking protein (S c 42
412707 AW206373 Hs 16443 Homo εapienε cDNA FLJ21721 fiε, clone C 42
442991 BE281238 Hs 8886 hypothetical protein FLJ20424 42
447439 AA313565 Hs 145020 ESTs Weakly similar to KIAA1205 protein 42
449685 AW296669 Hs 66095 ESTs 42
407204 R41933 Hε 140237 ESTs, Weakly similar to ALU1 HUMAN ALU S 42
450377 AB033091 Hs 74313 KIAA1265 protein 42
419647 AA348947 Hs 91816 hypothetical protein 42
442049 AA310393 Hs 190044 ESTs 42
430669 AW969657 Hs 291029 ESTs 42
424181 AL039482 Hs 142517 Homo sapiens mRNA, cDNA DKFZp434P0810 (f 41
443634 H73972 Hs 134460 ESTs 41
426216 N77630 Hs 13895 Homo sapiens cDNA FLJ11654 fis, clone HE 41
422634 NM 016010 Hs 118821 CGI-62 protein 4 1
445895 D29954 Hs 13421 KIAA0056 protein 41
447669 AL049985 Hs 19180 Homo εapiens mRNA, cDNA DKFZp564E122 (fr 41
407198 H91679 gb yv04a07 s1 Soares felal liver spleen 41
447752 M73700 Hs 105938 lactolransferπn 41
402855 NM.001839* Homo εapieπε calpoπiπ 3, acid 41
443161 AI038316 gb ox48c08 x1 Soareε total fetus Nb2HF8 41
415827 H17462 Hs 23079 ESTs 41
408161 AW952912 Hs 300383 hypothetical protein MGC3032 41
418365 AW014345 Hs 161690 ESTs 41
429525 N92540 Hs 205353 xtonucleoside tπphosphate diphosphohyd 41
435401 R44477 Hs 10056 hypothetical protein FLJ 14621 41
446657 AI335191 Hs 260702 ESTs, Weakly similar to 2109260A B cell 41
421141 AW117261 Hs 125914 ESTs 41
430335 D80007 Hs 239499 KIAA0185 protein 41
435020 AW505076 Hs 301855 DiGeorge syndrome critical region gene 8 41
445309 AL157474 Hs 12504 likely orlholog of mouse Arkadia 41
443547 AW271273 Hs 23767 hypothetical protein FU12666 41
410763 AF279145 Hs 8966 hypothetical protein FLJ21776 41
410592 R94088 Hs 43569 ESTs 41
423698 AA329796 Hs 1098 DKFZp434J1813 protein 41
428634 AA811845 Hs 106290 Kelch motif containing protein 41
430253 AK001514 Hs 236844 hypothetical protein FLJ10652 41
425211 M18667 Hs 1867 progastπcsm (pepsinogen C) 40
443273 AI042063 Hs 132156 ESTs 40
428055 AA420564 Hs 101760 ESTs 40
425707 AF115402 Hs 11713 E74-lιke fxtor 5 (ets domain transcript 40
451294 AI457338 Hs 29894 ESTs 40
430519 AF129534 Hs 49210 F-box only protein 4 40
441766 R53790 Hs 23294 hypothetical protein FU 14393 40
431117 AF003522 Hs 250500 delta (Droεophιla)-Iιke 1 40
446354 AW449650 Hε 346335 ESTs 40
451468 AW503398 Hs 293663 ESTs, Moderately similar to I38022 hypot 40
409706 BE158773 Hs 213207 ESTs 40
447082 T85314 thioredoxin like 40
418594 AI732083 Hs 187619 ESTs 40
426501 AW043782 Hs 293616 ESTs 40
436797 AA731491 Hs 334477 hypothetical protein MGC14879 40
416288 H51299 gb yp07c06 s1 Soareε breast 3NbHBst Homo 40
419865 NM 007020 Hs 93502 U1-εnRNP binding protein homolog (70kD) 40
425920 AL049977 Hε 162209 claudin 8 40
416658 U03272 Hε 79432 fibπllin 2 (congenital coπtractural ara 40
452367 U71207 Hs 29279 eyeε absent (Drosophila) homolog 2 40
433209 AB040907 Hs 278436 KIAA1474 protein 40
428801 AW277121 Hs 254881 ESTs 40
419629 AB020695 Hs 91662 KIAA0888 protein 40
451061 AW291487 Hs 213659 ESTs, Weakly similar to KIAA1357 protein 39
420544 AA677577 Hs 98732 Homo sapiens Chromosome 16 BAC clone CIT 39
400695 C11002514* gι|11280151|pιr||E82756 beta 39
417173 U61397 Hs 81424 ubiquitin like 1 (sentππ) 39
419985 H66373 Hs 5856 ESTε, Highly similar to bA393J163 [H sa 39
429340 N35938 Hs 199429 Homo sapiens mRNA, cDNA DKFZp434M2216 (f 39
433759 AA680003 Hs 109363 Homo sapiens cDNA FLJ23603 fis clone L 39 428862 NM 000346 Hs 2316 SRY (sex determining region Y) box 9 (ca 39
413450 Z99716 Hs 75372 N acetylgalactosammidase, alpha 39
427615 BE410107 Hs 179817 CGI 82 protein 39
450649 NM 001429 Hs 25272 E1 A binding protein p300 39
445798 NM 012421 Hs 13321 reaπanged L-myc fusion sequence 39
416198 H27332 Hs 99598 hypothetical protein MGC5338 39
431147 AI767751 Hs 20300 ESTs 39
439192 AW970536 Hs 105413 ESTs 39
446157 BE270828 Hs 131740 Homo sapienε cDNA FLJ22562 fiε, done H 39
451900 AB023199 Hs 27207 KIAA0982 protein 39
420802 U22376 Hs 1334 v myb avian myeloblastosis viral oncogen 39
426083 AW962712 Hs 126712 ESTs, Weakly similar to AF191020 1 E21G5 39
442320 AI287817 Hs 129636 ESTs 39
447541 AK000288 Hs 18800 hypothetical protein FLJ20281 39
444636 T96667 Hs 17877 ESTs 39
432103 T15803 Hs 272458 protein phosphatase 3 (formerty 2B), cat 39
412576 AA447718 Hs 107057 ESTs 39
423952 AW877787 Hs 136102 KIAA0853 protein 39
437916 BE566249 Hs 20999 hypothetical protein FLJ23142 39
442242 AV647908 Hs 90424 Homo sapiens cDNA FLJ23285 fis clone H 39
447280 BE617907 Hs 97635 ESTs 39
421750 AK000768 Hs 107872 hypothetical protein FLJ20761 38
450580 N40087 ESTs 38
432359 AA076049 Hs 274415 Homo sapiens cDNA FLJ 10229 fis, clone HE 38
429323 NM.001649 Hs 2391 apical protein, Xenopus laevis like 38
407332 AI801565 Hs 200113 Homo sapiens cDNA FLJ11379 fis, clone HE 38
426413 AA377823 gb EST90805 Synovial sarcoma Homo sapien 38
412652 AI801777 Hs 260024 ESTε 38
426226 AA769045 gb oa80h07 ε1 NCI CGAP_GCB1 Homo εapienε 38
437816 AI823445 Hs 280699 ESTε 38
444534 AW271626 Hs 42294 ESTs 38
459241 AA032276 Hs 99010 ESTs Moderately similar to T14342 NSD1 38
408242 AA251594 Hs 43913 PIBF1 gene product 38
443484 AI091458 Hs 134559 ESTs 38
422083 NM 001141 Hs 111256 arachidonate 15-lιpoxygeπase, εxoπd typ 38
428043 T92248 Hs 2240 uteroglobin 38
407192 AA609200 gb af12e02 ε1 Soareε.testis.NHT Homo sap 38
421590 AF004715 Hs 105940 jerky (mouse) homolog like 38
453020 AL162039 Hs 31422 Homo sapiens mRNA, cDNA DKFZp434M229 (fr 38
437372 AA323968 Hε 283631 hypothetical protein DKFZp547G183 38
432278 AL137506 Hs 274256 hypothetical protein FU23563 38
407917 U63139 Hs 41587 RAD50 (S cerevisiae) homolog 38
408547 AA574291 Hs 57837 ESTs 38
427635 BE397988 Hs 179982 tumor protein p53-bιπdιng protein 38
430968 AW972830 gb EST384925 MAGE resequences, MAGL Homo 38
452234 AW084176 Hε 223296 ESTs, Weakly similar to 138022 hypotheti 38
453698 AA037615 Hs 42746 ESTs 38
408875 NM.015434 Hs 48604 DKFZP434B168 protein 38
431197 AL038596 Hs 250745 poiy eraεe (RNA) III (DNA dirxted) (62k 38
434072 H70854 Hs 283059 Homo sapiens PRO1082 mRNA complete eds 38
438138 R98299 Hs 177502 ESTε 38
447906 AL050062 Hs 19999 DKFZP566K023 protein 38
415992 C05837 Hs 145807 hypothetical protein FU13593 37
435655 AW105663 Hs 6947 HSPC069 protein 37
430607 AW973521 Hs 247324 mitxhondπal nbosomal protein S14 37
439398 AA284267 Hs 221504 ESTs 37
448515 H68441 Hs 13528 hypothetical protein FU14054 37
445242 BE156478 Hs 21108 ESTs, Weakly similar to ALU1.HUMAN ALU S 37
418576 AW968159 Hs 289104 Epithelial calcium channel 2, CaT-like A 37
436024 AI800041 Hs 190555 ESTs 37
407783 AW996872 Hs 172028 a disintegnn and metalloprotemase doma 37
436207 AA334774 Hs 12845 hypothetical protein MGC13159 37
442861 AA243837 Hs 57787 ESTs 37
448207 AI475490 Hs 170577 ESTε 37
450628 AW382884 Hs 204715 ESTε 37
432606 NM.002104 Hs 3066 granzyme K (εeπne protease, granzyme 3, 37
438613 C05569 Hs 243122 hypothetical protein FLJ13057 similar to 37
443031 AW134696 Hs 49418 ESTs 37
447608 AW205042 Hs 18955 Homo sapiens cDNA FLJ20667 fis, clone KA 37
408312 AF263613 Hs 44198 intracellular membrane-assxiated calciu 37
412777 AI335773 Hs 270123 ESTs 37
424602 AK002055 Hs 151046 hypothetical protein FLJ 11193 37
424882 AI379461 Hs 153636 far upstream element (FUSE) binding prot 37
425898 AA365649 Hs 269478 ESTs, Weakly similar to PC4259 femtm 37
443323 BE560621 Hs 9222 eεtrogen rxeptor binding εite assxiate 37
452129 AW291379 Hs 212827 ESTε 37
453927 AA082465 Hs 125031 choliπe/ethanolammephosphotransferase 37
432336 NM.002759 Hs 274382 protein kinase, mterferon-inducible dou 37
425988 BE045897 Hs 274454 ESTs, Weakly similar to I38022 hypotheti 37
443123 AA094538 Hε 272808 putative transcnption regulation nuclea 37
445467 AI239832 Hs 15617 ESTs, Weakly similar to ALU4 HUMAN ALU S 37
423855 AA331761 Hs 254859 ESTs 37
403790 NM.001334* Homo sapiens cathepsin O (CTS 37 434470 AA634818 Hs 298138 ESTε 3 7
452032 BE244005 Hs 27610 retinoic acid and interferon inducible 37
420026 AI831190 Hε 166676 ESTs 37
421838 AW881089 Hs 108806 Homo sapienε mRNA, cDNA DKFZp566M0947 (f 37
449916 T60525 Hs 299221 pyruvate dehydrogenase kinase, isoenzyme 37
452270 AW975014 Hs 26 ferrochelataεe (protoporphyπa) 37
445941 AI267371 Hε 172636 ESTs 3 6
416882 AI633044 tryptophanyl tRNA synthetase 2 (mitochon 3 6
412533 AA679863 Hε 69606 ESTs 36
431740 N75450 Hs 183412 ESTs Moderately similar to AF116721 67 36
442710 AI015631 Hs 23210 ESTs 3 6
448212 AI475858 gb tc87d07 x1 NCI_CGAP_CLL1 Homo sapiens 3 6
413431 AW246428 Hs 75355 ubiquitin-coπjugating enzyme E2N (homolo 3 6
453038 AW292415 Hs 20509 HBV pX asεociated protein 8 36
427661 AA410292 Hs 104761 ESTε 36
420923 AF097021 Hs 273321 differentially expreεεed in hematopoieti 36
414844 AA296874 Hs 77494 deoxyguanosme kmase 3 6
441866 BE464341 Hε 21201 nedιn 3 DKFZP566B0846 protein 36
406815 AA833930 Hε 288036 tRNA isopentenylpyrophosphate transferaε 36
423482 BE280172 Hε 129228 galactokmase 2 36
424677 U09414 Hs 151689 zinc finger protein 137 (clone pHZ-30) 3 6
430160 AW968210 Hs 293957 ESTs, Weakly εimilar to ALUC.HUMAN »« 3 6
433672 BE281165 Hs 288038 TLS associated seπne-arginme protein 1 36
433887 AW204232 Hs 279522 ESTs 36
452670 AF068227 Hs 30213 ceroid lipofuscmoεiε, neuronal 5 3 6
411890 H92738 Hs 75811 N xylεphmgoεme amidohydrolase (acid c 36
432728 NM.006979 Hs 278721 HLA class II region expressed gene KE4 36
431724 AA514535 Hs 283704 ESTs 36
435703 AW630133 Hs 83313 GK003 protein 3 6
445674 BE410347 Hs 13063 transcnption factor CA150 36
414178 AW957372 Hs 46791 ESTs, Weakly similar to I38022 hypotheti 36
416111 AA033813 Hs 79018 chromatin assembly factor 1 , subunit A ( 3 6
432840 AK001403 Hs 279521 hypothetical protein FLJ20530 3 6
439726 AW449893 Hs 293707 ESTs, Weakly similar to I38598 zinc fing 36
445704 AI493742 Hs 167700 ESTs, Moderately similar to I38022 hypot 36
449115 AW959952 Hs 37528 ESTs Weakly similar to AF090944 1 PRO06 3 6
439379 AA835002 Hs 125611 ESTs 36
414646 AA353776 Hs 901 CD48 antigen (B-cell membrane protein) 36
434579 T55958 gb yb35f05 r1 Stratagene fetal spleen (9 36
451367 AA923729 Hs 26322 cell cycle related k ase 3 6
420285 AA258124 Hs 293878 ESTs, Moderately similar to ZN91.HUMAN Z 36
431263 AW129203 Hs 322915 ESTs 36
431952 Z70695 Hs 272240 Homo sapienε cDNA FLJ 11086 fis, clone PL 36
439092 AA830149 gb x44f08 s1 NCI_CGAP_GCB1 Homo εapienε 3 6
411562 AL050201 Hs 70769 hypothetical protein DKFZp586E1923 35
417771 AA804698 Hs 82547 retinoic xid rxeptor reεpoπder (tazaro 35
419440 AB020689 Hs 90419 KIAA0882 protein 35
417333 AL157545 Hs 173179 bromodomam and PHD finger containing, 3 35
419241 AA523939 Hs 165258 ESTs 35
410762 AF226053 Hs 66170 HSKM-B protein 35
413384 NM 000401 Hs 75334 exostoses (multiple) 2 3 5
424081 NM 006413 Hs 139120 πbonucleaεe P (30kD) 35
428004 AA449563 Hs 151393 glutamate-cyεteme ligase, catalytic sub 35
420390 AA330047 Hs 191187 ESTs 3 5
416662 T25853 Hs 7538 ESTs 35
433280 AA581404 Hs 289037 Homo sapiens cDNA FLJ14135 fis, clone MA 35
433285 AW975944 Hs 237396 ESTs 35
421991 NM 014918 Hs 110488 KIAA0990 protein 3 5
413950 AA249096 Hs 32793 ESTs 35
431318 AA502700 Hs 293147 ESTs, Moderately similar to A46010 X-lm 35
400289 X07820 Hs 2258 matnx metalloprotemase 10 (stromelysin 3 5
411149 N68715 Hε 269128 ESTs 35
417601 NM.014735 Hs 82292 KIAA0215 gene product 35
418334 AA319233 Hs 5521 ESTs 35
422583 AA410506 Hs 27973 KIAA0874 protein 35
425717 X07282 Hs 171495 retinoic xid receptor, beta 35
425856 AA364908 Hs 98927 hypothetical protein FLJ13993 35
434569 AI311295 Hs 344478 KIAA0196 gene product 35
419436 AA991639 Hs 242413 hypothetical protein DKFZp434K1421 35
437296 AA350994 Hs 20281 KIAA1700 35
432697 AW975050 Hε 293892 ESTs, Weakly similar to ALU4 HUMAN ALU S 3 5
439605 AF086431 Hs 22380 ESTε 35
442145 AI022650 Hs 8117 erbb2 interacting protein ERBIN 35
432589 AL135725 Hε 131708 ESTε 3 5
425910 AA830797 Hs 184760 CCAAT-box-biπdmg tranεcπption factor 3 5
412095 AI624707 Hs 5921 Homo εapiens cDNA FLJ21592 fis, clone C 35
421129 BE439899 Hs 89271 ESTs 35
429433 AA452899 Hs 213586 ESTs, Weakly similar to KIAA1353 protein 35
434839 AI743069 Hs 134736 ESTs 3 5
435166 AI391470 Hs 158618 ESTs 35
448966 AW372914 Hs 86149 phosphomositol 3-phosphate binding prot 35
449318 AW236021 Hs 78531 Homo sapienε, Similar to RIKEN cDNA 5730 3 5
453311 AW104911 Hε 126707 hypothetical protein FLJ 11457 3 5 456497 AW967956 Hs 123648 ESTs, Weakly similar to AF108460 1 ubinu 35
413786 AW613780 Hs 13500 ESTs 35
430935 AW072916 zinc finger protein 131 (clone pHZ-10) 35
439904 AW892676 gb CM3-NN0004-280300 131-c12 NN0004 Homo 35
449909 AA004681 Hs 59432 ESTs 35
445817 NM 003642 Hs 13340 histone xetyltransferase 1 35
419594 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 35
417251 AW015242 Hs 99488 ESTs, Weakly similar to YK54_YEAST HYPOT 35
423545 AP000692 Hs 129781 chromoεome 21 open reading frame 5 35
438527 AI969251 Hs 115325 RAB7, member RAS oncogene family like 1 35
453916 AW974874 Hε 75212 ormthme dxarboxylaεe 1 35
430200 BE613337 Hε 234896 geminm 34
437187 AL080208 Hε 306325 Homo εapienε mRNA, cDNA DKFZp586C1523 (f 34
423645 AI215632 Hε 147487 ESTε 34
432370 AA308334 Hs 274424 N-xetylneuraminic acid phoεphate syntha 34
434966 AA657494 gb nt66f04 s1 NCI_CGAP_Pr3 Homo εapiens 34
404571 NM 015902" Homo sapienε progestin induce 34
418727 AA227609 Hs 94834 ESTs 34
436374 AA400709 Hs 96716 ESTs Weakly similar to T17210 hypotheti 34
452721 AJ269529 Hs 301871 solute earner family 37 (glyceroI-3 pho 34
427472 AA522539 Hs 131250 transposon-deπved Buster3 transposase I 34
418245 AA088767 Hs 83883 transmembrane, prostate androgen induced 34
402031 ENSP00000251056* Plasma membrane calcium 34
407137 T97307 gb ye53h05 s1 Soares fetal liver εpleen 34
449603 AI655662 Hs 197698 ESTε 34
425692 D90041 Hs 155956 N acetyltransferase 1 (arylamine N acety 34
436805 AA731533 Hs 270751 ESTs 34
437367 AA749316 Hs 271879 ESTs, Moderately similar to ALU1_HUMAN A 34
407908 BE379758 Hs 110853 uncharacteπzed hematopoietic stem/proge 34
430144 AI732722 Hs 187694 ERGL protein, ERGIC-53-lιke protem 34
416292 AA179233 Hs 42390 nasopharyngeal carcinoma susceptibility 34
423800 AA331156 gb EST35034 Embryo, 6 week, subtracted ( 34
439375 AA689526 Hs 344249 steroid dehydrogenase homolog 34
429084 AJ001443 Hs 195614 splicing fxtor 3b, subunit 3, 130kD 34
432886 BE159028 Hs 279704 chromatin accessibility complex 1 34
408267 AW380525 Hs 343564 tubulin specific chaperone e 34
408832 AW085690 Hs 63428 ESTs, Weakly similar to Z195 HUMAN ZINC 34
422564 AI148006 Hs 222120 ESTs 34
424842 AA034127 Hε 153487 signal transducing adaptor molxule (SH3 34
429984 AL050102 Hε 227209 hypothetical protein FLJ21617 34
435256 AF193766 Hs 13872 cytokine like protein C17 34
436137 AI056769 Hs 133512 ESTs 34
440348 AW015802 Hs 47023 ESTs 34
442910 AI365130 Hs 11307 ESTs, Weakly similar to T19326 hypotheti 34
443242 BE243910 Hs 9082 nucleopoπn p54 34
445469 AW298370 Hs 153714 complement-c1q tumor nxrosiε fxtor-rel 34
449517 AW500106 Hs 23643 εeπne/threonine protein kinaεe MASK 34
425354 U62027 Hs 155935 complement component 3a rxeptor 1 34
433037 NM 014158 Hs 279938 HSPC067 protein 34
423044 AA320829 Hs 97266 protocadhenn 18 34
434128 W93170 Hs 284164 protein x 0004 34
449845 AW971183 Hs 9683 DnaJ (Hεp40) homolog, εubfamily C, membe 34
423590 AW952412 Hs 65874 ESTε, Weakly similar to A40348 Elav/Sex- 34
440370 AA884000 Hs 8173 hypothetical protein FLJ10803 34
438825 BE327427 Hs 79953 ESTs 34
446874 AW968304 Hs 56156 ESTs 34
408101 AW968504 Hs 123073 CDC2-related protein kinase 7 34
419131 AA406293 Hs 41167 ESTs 34
423178 AI033140 Hs 124983 Homo sapienε mRNA, cDNA DKFZp564C142 (fr 34
433764 AW753676 Hs 39982 ESTε 34
440658 H29142 Hs 143032 ESTε, Weakly similar to neuronal thread 34
411558 AA102670 Hs 70725 gamma-aminobutyπc xid (GABA) A rxepto 33
452815 AA418841 gb zw01e11 s1 Soareε NhHMPu SI Homo εapi 33
421234 AA907153 Hs 190060 ESTε 33
424075 AI807320 Hs 227630 RE1-sιlencιng transcnption fxtor 33
412045 AA099802 Hε 83883 transmembrane, prostate androgen induced 33
420041 AB005142 Hs 94592 klotho 33
426174 AA547959 Hs 115838 ESTε 33
427083 NM 006363 Hs 173497 Sx23 (S cerevisiae) homolog B 33
441021 AW578716 Hs 7644 H1 histone family, member 2 33
436664 AW197887 Hs 253353 ESTs 33
441124 T97717 Hs 119563 ESTs 33
444169 AV648170 Hs 58756 ESTs 33
421476 AW953805 Hs 21887 ESTs 33
422165 AL041199 Hs 1481 histidine dxarboxylase 33
455100 BE160198 gb QV1-HT0413 010200 059 h03 HT0413 Homo 33
450747 AI064821 Hs 318535 ESTs, Highly similar to 1818357A EWS gen 33
401197 ENSP00000229263* HSPC213 33
433404 T32982 Hs 102720 ESTs 33
422546 AB007969 Hs 301478 KIAA0500 protein 33
443884 N20617 Hs 194397 leptm rxeptor 33
414341 D80004 Hs 75909 KIAA0182 protein 33
425292 NM_005824 Hs 155545 37 kDa leucine πch repeat (LRR) protein 33 414407 AA147026 Hε 76704 ESTs 33
420324 AF163474 Hε 96744 prostate androgen regulated transcript 1 33
423453 AW450737 Hs 128791 CGI 09 protein 33
444170 AW613879 Hs 102408 ESTs 33
445474 AI240014 Hs 259558 ESTs 33
450582 AI339732 G πch RNA sequence binding factor 1 33
451246 AW189232 Hε 39140 cutanxus T cell lymphoma tumor antigen 33
434194 AF119847 Hs 283940 Homo sapiens PRO1550 mRNA partial eds 33
444324 AI301330 Hs 143838 ESTs 33
427581 NM 014788 Hs 179703 KIAA0129 gene product 33
429258 AA448765 gb zx10e09 r1 Soares_total_fetus_Nb2HF8_ 33
400880 NM_000611* Homo εapiens CD59 antigen p18 33
445525 BE149866 Hs 14831 Homo sapienε, Similar to zinc finger pro 33
451968 H56196 Hs 26409 Homo sapiens mRNA, cDNA DKFZp547K204 (fr 33
411190 AA306342 Hs 69171 protein kinase Clike 2 33
410660 AI061118 Hs 65328 Fanconi anemia, complementation group F 33
420493 AI635113 Hs 270366 ESTs Weakly similar to I78885 seππe/th 33
423740 Y07701 Hs 293007 aminopeptidase puromycin sensitive 33
428523 AW974540 Hs 98626 ESTs 33
428743 AL080060 Hs 301549 Homo sapiens mRNA, cDNA DKFZp564H172 (fr 33
432363 AA534489 gb nf76g11 s1 NCI_CGAP_Co3 Homo sapiens 33
435102 AW899053 Hs 76917 F-box only protem 8 33
438147 AW250553 H 2K binding fxtor-2 33
445808 AV655234 ESTs, Moderately similar to PC4259 fern 33
453058 AW612293 Hs 288684 Homo sapiens cDNA FLJ11750 fis, clone HE 33
453286 AA034319 Hs 29041 Homo sapiens cDNA FLJ14177 fis, clone NT 33
453802 AL134757 gb DKFZp547G1090_r1 547 (synonym hfbrl) 33
422017 NM.003877 Hs 110776 STAT induced STAT inhibitor 2 33
411373 BE326276 Hs 8861 ESTs 33
435114 AA775483 Hs 288936 mitochondnal πboεomal protein L9 33
443674 AI081330 Hs 145008 ESTε 33
427528 AU077143 Hs 179565 mmichromoεome maintenance deficient (S 33
433800 AI034361 Hs 135150 lung type I cell membrane assxiated gly 33
420969 AI636310 Hs 28310 ESTs 33
421654 AW163267 Hs 106469 suppressor of varl (S cerevisiae) 3-lιke 33
409542 AA503020 Hs 36563 hypothetical protein FU22418 33
410119 F07841 Hs 13926 ESTs 33
417379 AA196390 gb zp99b10 s1 Stratagene muεcle 937209 H 33
423201 NM 000163 Hs 125180 growth hormone receptor 33
442787 W93048 Hs 250723 hypothetical protein MGC2747 33
407930 AA045847 Hs 188361 Homo sapiens cDNA FU12807 fis, clone NT 33
423427 AL137612 Hs 285848 KIAA1454 protein 33
424903 T26477 Hs 22883 ESTs, Weakly similar to I38022 hypotheti 33
426775 AA384564 ESTs 33
432378 AI493046 Hε 146133 ESTs 33
438875 AA827640 Hε 189059 ESTs 33
452959 AI933416 Hε 189674 ESTs 33
453124 AI139058 Hε 125790 leucine πch repeat-containing 2 33
417560 U73338 Hε 82283 5-methyltetrahydrofolate-hom∞ysteιne me 32
433002 AF048730 Hε 279906 cyclin T1 32
430929 AA489166 Hε 156933 ESTε 32
437444 H46008 Hs 31518 ESTε 32
446297 AI346930 Hs 149728 ESTs 32
407870 AB032990 Hs 40719 hypothetical protein KIAA1164 32
429377 AA813192 Hs 200596 KIAA0547 gene product 32
426030 BE243933 Hs 108642 z o finger protein 22 (KOX 15) 32
420583 H77859 Hs 65450 reticulon 4 32
425264 AA353953 Hs 20369 ESTs, Weakly similar to gonadotropm ind 32
442562 BE379584 dolichyl-diphosphooligosxchaπde-protei 32
418871 NM.001608 Hε 1209 xyl-Coenzyme A dehydrogenase, long chai 32
421029 AW057782 Hε 293053 ESTs 32
452997 N64777 Hs 44656 ESTs 32
435035 BE568487 Hs 47668 x 006 protein 32
408412 AW193033 Hs 124436 ESTs 32
421684 BE281591 Hs 106768 hypothetical protein FLJ10511 32
421887 AW161450 Hs 109201 CGI-86 protein 32
432409 AA806538 Hs 130732 KIAA1575 protein 32
434378 AA631739 Hs 335440 EST 32
409401 AI201895 Hs 181309 proteasome (prosome, mxropain) subunit, 32
420195 N44348 Hs 26243 Homo sapiens cDNA FLJ 11177 fis, clone PL 32
410264 AK001853 Hs 61508 Homo sapiens cDNA FU10991 fis, clone PL 32
410296 AW630675 Hs 271946 ESTs 32
413838 AV661185 Hs 75574 mitxhondπal nbosomal protein L19 32
414342 AA742181 Hs 75912 KIAA0257 protein 32
414709 AA704703 Hε 77031 Sp2 transcnption fxtor 32
425475 W56339 Hε 107057 ESTε 32
437814 AI088192 Hs 135474 ESTs, Weakly similar to DDX9.HUMAN ATP-D 32
449897 AW819642 Hs 24135 transmembrane protein vezatm, hypotheti 32
452295 BE379936 Hs 28866 programmed cell death 10 32
437517 AI927675 Hs 244482 Homo εapiens, clone IMAGE 3611719, mRNA, 32
432960 AW150945 Hs 144758 ESTs 32
452498 AK000101 Hs 29700 hypothetical protein FLJ20094 32
427299 AA830210 Hs 214263 ESTs, Moderately similar to ALU1.HUMAN A 32 421645 AA974127 Hs 129777 ESTs 32
457489 AI693815 Hs 127179 cryptic gene 32
415691 AW963979 Hε 24723 ESTs 32
433852 AI378329 Hε 126629 ESTs 32
439735 AI635386 Hs 142846 hypothetical protein 32
428279 AA425310 Hs 155766 ESTs, Weakly similar to A47582 B cell gr 32
427715 BE245274 Hs 180428 KIAA1181 protein 32
408699 AA056614 Hs 106200 ESTs Moderately similar to ZN91_HUMAN Z 32
415715 F30364 Hs 302204 ESTs 32
426172 AA371307 Hs 125056 ESTs 32
434825 N87549 Hs 125287 zinc finger protein ZNF140 like protem 32
436246 AW450963 Hs 119991 ESTs 32
436401 AI087958 Hs 29088 ESTs 32
408784 AW971350 Hs 63386 ESTs 32
432125 AW972667 Homo sapiens cDNA FLJ12300 fis, clone MA 32
426716 NMJ06379 Hs 171921 sema domain, immunoglobulin domain (Ig), 32
405558 Target Exon 32
434747 AA837085 Hs 220585 ESTs 32
414591 AI888490 Hs 55902 ESTs, Weakly similar to ALU8JHUMAN ALU S 32
426991 AK001536 Homo sapienε cDNA FLJ10674 fis, clone NT 32
426171 AI128606 Hs 6557 zinc finger protein 161 32
402802 NM_001397 Homo sapiens endothelin conver 32
412530 AA766268 Hs 266273 hypothetical protein FLJ13346 32
433050 AI093930 Hs 163440 Homo sapiens cDNA FU21000 fis, clone C 32
439221 AA737106 Hs 32250 ESTs, Moderately similar to 178885 senn 32
440351 AF030933 HS 7179 RAD1 (S pombe) homolog 32
445218 T79971 Hs 12432 Homo sapiens clone 24407 mRNA sequence 32
448568 AA149121 Hs 71947 ESTs 32
420131 F08286 Hs 95262 nuclear factor related to kappa B bindin 31
429299 AI620463 Hs 347408 hypothetical protein MGC13102 31
407913 BE393767 Hs 41569 phosphatidic acid phosphatase type 2A 3 1
415009 C75253 Hs 220950 ESTs 3 1
406627 T64904 Hs 163780 ESTs 3 1
438666 AW014493 Hε 126727 ESTs 3 1
419875 AA853410 Hε 93557 proeπkephalm 3 1
456660 AA909249 Hε 112282 solute camerfamily 30 (zinc transport 3 1
418701 AA814948 Hε 96343 ESTs, Weakly similar to ALUC.HUMAN «" 3 1
425071 NM 013989 Hs 154424 deiodmase, lodothyroπme, type II 31
440300 N39760 Hs 8859 Homo sapiens, Similar to RIKEN cDNA 5830 31
444100 AA383343 Hs 22116 CDC14 (cell division cycle 14, S cerevi 31
431416 AA532718 Hs 178604 ESTs 3 1
422662 BE274778 Hs 119007 RAB4, member RAS oncogene family 3 1
449543 AF070632 Hs 23729 Homo sapiens clone 24405 mRNA sequence 3 1
437083 AW082597 Hs 244862 ESTs 3 1
430294 AI538226 Hs 32976 guanine nucleotide binding protein 4 3 1
417380 T06809 Hs 332086 ESTs 3 1
419965 H16382 Hs 70258 ESTs 3 1
430039 BE253012 Hs 153400 ESTs, Weakly similar to ALULHUMAN ALU S 3 1
430188 AL049242 Hs 234794 Homo sapienε mRNA, cDNA DKFZp564B083 (fr 3 1
446146 AI287539 Hs 148078 ESTs 31
426647 AA243464 Hs 294101 pre B-cell leukemia transcnption fxtor 31
418555 AI417215 Hs 87159 hypothetical protein FLJ12577 3 1
453496 AA442103 Hε 33084 solute earner family 2 (facilitated glu 31
423947 AW451954 Hε 135941 KIAA1048 protein 31
451893 AW192083 Hε 290855 ESTε 31
447726 AL137638 Hε 19368 matπliπ 2 31
415068 Z19448 Hε 131887 ESTε, Weakly εimilar to T24396 hypotheti 3 1
453439 AI572438 Hs 32976 guanine nucleotide binding protein 4 3 1
443331 AI052026 Hs 149995 ESTs 31
410340 AW182833 Hs 112188 hypothetical protein FLJ13149 31
414372 AA143654 gb zo65a02 r1 Stratagene pancreas (93720 3 1
427421 AA402414 Hs 3059 coatomer protein complex subunit beta 3 1
429399 AA452244 Hs 16727 ESTs 31
430092 AI821399 Hs 16514 ESTs 31
433577 AW007080 Hs 284192 ESTs 3 1
433730 AK002135 Hs 3542 hypothetical protein FU11273 3 1
436894 H80696 Hs 233313 ESTs 3 1
437756 AA767537 Hs 197096 ESTs 31
438979 AW976218 Hs 32565 ESTs 3 1
441791 AW372449 Hs 61271 hypothetical protein FU21159 3 1
457718 F18572 Hs 22978 ESTs, Weakly similar to ALU4.HUMAN ALU S 3 1
452017 AF109302 Hs 27495 prostate cancer aεsociated protein 7 31
419030 T79957 Hs 188466 ESTs 31
438308 AI343469 Hs 127685 KIAA1627 protein 3 1
433571 AA765256 Hs 135191 ESTs, Weakly similar to unnamed protein 3 1
421685 AF189723 Hs 106778 ATPase, Ca transporting type 2C, member 3 1
428878 AA436884 Hs 48926 ESTs 3 1
432205 AI806583 Hs 125291 ESTs 3 1
440099 AL080058 Hs 6909 DKFZP564G202 protein 3 1
428259 AA424793 Hs 24144 ESTs 3 1
434614 AI249502 Hs 29669 ESTs 3 1
420380 AA640891 Hs 102406 ESTs 3 1
433323 AA805132 Hs 159142 ESTs 31 439544 W26354 Hs 28891 hypothetical protein FLJ 11360 artemis p 31
412088 AI689496 Hs 108932 ESTε 31
434361 AF129755 Hs 88474 ESTs 31
400664 NMJ02425 Homo sapienε matrix metallopro 31
436354 AI879252 Hs 5151 RAN binding protein 7 31
449474 AA019344 Hs 2055 ubiquitm-activating enzyme E1 (A1S9T an 31
410595 AW629223 Hs 64794 zinc finger protein 183 (RING finger, C3 31
415245 N59650 Hs 27252 ESTs 31
418647 AA226198 gb nc26a07 s1 NCI.CGAP.Pr1 Homo εapienε 3 1
434808 AF155108 Hs 256150 Homo εapieπs, Similar to RIKEN cDNA 2810 31
453716 AA037675 Hs 152675 ESTε 31
432952 AA813887 Hs 188173 Homo εapieπs cDNA FLJ12187 fis, clone MA 30
408705 AA312135 Hs 46967 HSPC034 protein 30
430280 AA361258 Hs 237868 interleukin 7 receptor 30
445919 T53519 Hs 334692 hypothetical protein MGC14141 30
441790 AW294909 Hs 132208 ESTs 30
414085 AA114016 Hs 75746 aldehyde dehydrogenase 1 family, member 30
452619 AW298597 Hs 61884 Homo sapiens, clone IMAGE 4298026, mRNA, 30
422788 AL117352 Hs 77196 Human DNA sequence from clone RP5-876B10 30
439703 AF086538 Hs 196245 ESTs 30
444489 AI151010 Hε 157774 ESTs 30
453878 AW964440 Hε 19025 DC32 30
440193 AW902312 Hs 7037 Homo sapiens clone 24923 mRNA sequence 30
433680 AI805366 Hs 199945 ESTs 30
426363 M58524 Hs 2025 transforming growth factor, beta 3 30
447595 AW379130 Hs 18953 phosphodiesterase 9A 30
426044 AA502490 Hs 170290 ESTs 30
431962 AL049385 Hs 272251 Homo sapiens mRNA cDNA DKFZp586M1418 (f 30
445084 H38914 Hs 250848 hypothetical protein FLJ14761 30
452737 AK001680 Hε 30488 DKFZP434F091 protem 30
458229 AI929602 Hs 177 phosphatidylinositol glycaπ, class H 30
435712 AA694607 Hs 176956 ESTs 30
407378 AA299264 Hs 57776 ESTs, Moderately similar to I38022 hypot 30
414993 AW819403 Hs 77724 KIAA0586 gene product 30
419459 AW291128 Hs 278422 DKFZP586G1122 protein 30
421988 AW450481 Hs 161333 ESTs 30
432833 N51075 Hs 110028 ESTs 30
445210 H09323 Hs 27133 ESTs 30
447620 AW290951 Hs 224965 ESTs 30
449375 R07114 Hs 271224 ESTs 30
428695 AI355647 Hs 189999 purmergic receptor (family A group 5) 30
443967 AW294013 Hs 200942 ESTs 30
441224 AU076964 Hs 7753 calumenm 30
448822 BE149845 Hs 289038 hypothetical protein MGC4126 30
435688 H72286 Hs 128387 ESTs 30
441889 AI090455 Hs 268371 hypothetical protein FLJ20274 30
411704 AI499220 Hs 71573 hypothetical protein FLJ10074 30
415954 AA171850 Hε 42251 ESTε 30
419544 AI909154 gb QV-BT200-010499-007 BT200 Homo εapien 30
420077 AW512260 Hε 87767 ESTε 30
443475 AI066470 Hs 132809 ESTε 30
447231 AK001293 Hs 330208 crystallm, zeta (quinone redudase) lik 30
438436 AA807168 Hs 271552 ESTs 30
427871 AW992405 Hs 59622 Homo sapiens, clone IMAGE 3507281, mRNA, 30
443280 AA299688 Hs 24183 ESTs 30
448264 AI478933 Hs 188260 ESTs 30
428673 AW601325 Hs 337757 Homo sapienε mRNA, cDNA DKFZp566M063 (fr 30
453843 D25215 Hs 35804 hxtdomam aπd RLD 3 30
400303 AA242758 Hs 79136 UV-1 protein, eεtrogen regulated 30
445943 AW898533 Hs 181574 ESTs 30
432286 AW327432 Hs 255843 ESTs 30
431707 R21326 Hs 267905 hypothetical protein FU10422 30
432675 AI791855 Hs 105884 ESTs 30
443162 T49951 Hs 9029 DKFZP434G032 protein 30
448073 W19789 Hs 336635 Homo sapienε, clone IMAGE 4179482, mRNA 30
419713 AW968058 Hs 92381 nudix (nucleoside diphoεphate linked moi 30
447966 AA340605 Hs 105887 ESTs, Weakly similar to Homolog of rat Z 30
423583 AL122055 Hs 129836 KIAA1028 protein 30
418304 AA215702 gb zr97g10 r1 NCI.CGAP.GCB1 Homo sapiens 30
417206 AA291183 Hs 81648 hypothetical protein FU11021 similarto 30
410011 AB020641 Hs 57856 PFTAIRE protein kinase 1 30
411850 AK002033 Hs 72782 hypothetical protein FLJ11171 30
438986 AF085888 Hs 269307 ESTs 30
445921 AW015211 Hs 146181 ESTs 30
447124 AW976438 Hs 17428 RBP1-iιke protein 30
452953 AI932884 Hs 271741 ESTs, Weakly similar to A46010 X linked 30
TABLE 60B
Pkey Unique Eos probeset identifier number CAT number: Gene cluster number Accesεion: Genbank accession numbers
Pkey CAT Number Accessions
411479 1247077.1 AW848047 AW848202 AW848631 AW848142 AW848702 AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069
AW848905 AW848214
411667 12533341 BE160198 AW935898 T11520 AW935930 AW856073 AW861034 414372 143909.Ϊ AA143654 AW753140 AA213770 AW970865 AA569075 AA492132 414680 147525.1 AA743331 AA837388 AW664540 AA775711 AA150965 BE465475 AA968994 AA886905 AI141054 AW194991 AA252147 AA319500 AI184288
AA708749 AA644620 AA652769 AA242975 AA151074 T19890
415989 156454.1 AI267700 AI720344 AA191424 AI023543 AI469633 AA172056 AW958465 AA172236 AW953397 AA355086 416288 15859831 H51299 H44619 H46391 R86024 H51892 T72744 416882 162718.T AI633044 AW016212 AW241143 AA769058 R43272 AW068958 AA210918 AA293774 AI748815 AI763294 AI333114 AI277384 AI088297 AI468477
AI824624 AW189606 AI631751 Z40749 AI984673 AI671316 AA189024 AW235412 BE178426 R24677 R40635 H05100 R40597
416913 163001.1 AW934714 BE161007 BE162500 AW749902 AW749864 BE162498 BE161005 AA190449 AW513465 BE161006 BE162499 417379 167238.1 AA196390 AA507837 AA196468 418304 173658.2 AA215702 AA368006 AA215703 BE066555 BE006876 418647 177521.1 AA226198 AA226513 AA383773 418866 179788.1 T65754 AA229857 AA229658 419536 185688.1 AA603305 AA244095 AA244183 419544 185760.2 AI909154 AA526337 AA244193 AI909153 423412 228001 1 AF109300 AI299378 AI202654 423800 232161 1 AA331156 AA331157 AA331155 426226 262918.1 AA769045 AA372590 AW963633 426413 266650.1 AA377823 AW954494 AI022688 426503 268283.1 AA380153 AA380233 AW963529 426775 271683.1 AA384564 AW966475 H02121 N41297 D63213 AA886888 AI922414 AW044240 AW196808 AI076736 AA599294 AI954433 AW117617 AI640323
H98134
426991 27415.1 AK001536 AA191092 AW510354 AI554256 AL353968 AA134266 428342 290035.2 AI739168 AA426249 AI199636 AW505198 AW977291 AA824583 AA883419 AA724079 AI015524 AI377728 AW293682 AI928140 AA731438
A1092404 AI085630 AA731340
429163 3005431 AA884766 AW974271 AA592975 AA447312 429220 301384.1 AW207206 AW341473 AA448195 AI951341 429258 3019171 AA448765 C04967 C03045 AA658293 430935 325772.1 AW072916 AI184913 AA489195 AW466994 AW469044 N59350 AI819642 AI280239 AI220572 AA789302 AI473611 AW841126 D60937 430968 326269J AW972830 AA527647 AA489820 AA570362 431429 333131 AF072813 AF119297 AA362885 AF059524 NM.006054 AA157365 AW163623 AA056148 AA227062 AA418057 AA227076 AA078753 AA233594
D58629 AA232373 AA233577 T35956 BE618035 AA354497 AA359082 T32010 AA134519 BE299901 BE268096 BE396826 AA324268 AL120308
AA187561 AA311680
432093 341283.1 H28383 AW972670 H28359 AA525808 432125 3417761 AW972667 AA526539 AI057032 AW167842 432189 342819.1 AA527941 AI810608 AI620190AA635266 432340 345248.1 AA534222 AA632632 T81234 432363 3454691 AA534489 AW970240 AW970323 432600 350959.1 AI821085 AW973464 AA554802 AI821831 AA657438 AA640756 AA650339 432810 354375.1 AA863400 AI991439 AW016017 AW014704 AI367512 H17550 AA744752 R46187 AW471324 AI126670 AA626033 AI276287 AI094253 AI286003
AI147163 AI911443 AW512612 AA972102 AA999975 AI684428 AI335035 D63102 AI524234 AI539156 AA565542
434579 389161 T55958 T57205AF147346 434966 396504.1 AA657494 AI582663 AI581639 435023 398093.1 AI692552 AI393343 AI800510 AI377711 F24263 AA661876 437866 444332 AA156781 AW293839 U52054 AA024963AA778446 BE073977 AW444904AW602574 BE164040 BE164012 BE163972 BE163974 BE163992
AA837481 AW468444 BE185091 AW468002 AA687333 AA811830 AA581806 AI866686 AI572124 AA043777 AA040926 D20160 AI536733
AA812489 A 874142 AI47188
438147 45074.1 AW250553 L07876 Z36843 R30693 AI190097 AW965317 439092 4685541 AA830149 AW978407 M85983 AW503637 439518 47334.1 W76326 AF086341 W72300 439904 479942.1 AW892676 AA853877 D44747 440840 50357.2 AW629666 AW959831 AW205739 BE620243 AA412367 AW300025 AW051920 AI288591 AW236114 AI302852 AI038548 AA534496 AI797207
AA921877
441102 509604.1 AA973905 AI299888 AA917019 H63235 T90771 442562 54500.2 BE379584 R34211 BE544768 AW973709 AI653056 AI653173 AI266043 AI656750 H74180 AI492830 AI376090 AI472184 D59940 AW170056
AI082443 AW021142 AI167921 AI348677 AI278577 AW130886 AA761517 AI698203 AA115535 AI264790 R34328 D59939 AW205074 AA554902
D62102AI0007
443161 561305.1 AI038316 AI344631 A1261653 445808 651331 AV655234 AW966332 AA340239 447082 7072481 T85314 AI360684 T85528 T91254 448212 755099.1 AI475858 AW969013 449625 8113.1 NM.014253 AF100772 BE088769 AL022718 BE161779 AW863569 BE161640 AL039060 BE168542 AW296554 AA323193 AA235370 AW779760
N48674 AI375997 R45432 D59344 AI203107 F07491 R35360 F125094 AI913631 AI498402 T61382 AI016320 N45526 T61415 AA331486
450580 839291 N40087 H12925 AA460779 AA096372 BE160847 AW816890 AW816893 AW816577 AW816891 AW816882 AW816868 AW816889 AW816940
AW816892 AW816941 AW816578 AA029183T83320 H86850 AA010295 BE160823 Z25353 AA150883 AW887764 AW023806 AW022095
AA164518 AA730973 W00417 W65303
450582 83933.1 AI339732AA010300 AW515041 AA768334 N29860 AA425874AA425118 AA865829 AW936878 452260 9074.1 AA453208 NMJ04251 U44103 AI671547 N57463 AW007521 AI479232 T82809 R67109 AW796099 AI833027 AI765395 AI763029 AI758228
BE326331 AI934576 AI922378 AW276431 AI718466 N36566 AA904753 BE464245 AI338752 AI659875 AW272338 AI423136 AI089270 AH 60904
AA664354 BE1
452598 92338.2 AI831594 AW970667 AW027959 AI129800 AI927949 AI650270 AI625105 AW514661 AI708393 AL138076 BE180510 AI926721 AI399955 AA749139
AI862160 AW874011 AI242763 AA262795 AA039864 H73499 AI093249 BE245661 AI816834 N25206 AA828301 AI084565 AI302816 AA026905
AA77255
452815 93255.1 AA418841 AI452657 AI768876 AA028973 BE179873 C00215 AA418930 453802 981589.1 AL134757 AW079131 455100 1253334.1 BE160198 AW935898 T11520 AW935930 AW856073 AW861034 457728 393853 1 AW974811 AA651634 AA650072
TABLE 60C
Pkey Unique number correεpondmg to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exonε were predicted
Nt position Indicates nucleotide positions of predicted exonε
Pkey Ref Strand NLposition
400664 8118496 Plus 13558-13721,13942-14090,14554-14679
400695 7249150 Plus 160456-160567,164757-164873
400880 9931121 Plus 29235-29336,36363-36580
401197 9719705 Plus 176341-176452
401424 8176894 Plus 24223-24428
401451 6634068 Mmuε 119926-121272
401519 6649315 Pluε 157315-157950
401558 7139678 Plus 103510-104090
402031 7656761 Plus 33080-33263,33939-34094,36103-36507
402802 3287156 Minus 53242-53432
402855 9662953 Minus 5976359909
403046 3540153 Minus 55707-55859,56369-56511
403047 3540153 Minus 59793-59968
403790 8084957 Minus 87826-87947,89835-90002
404571 7249169 Minus 112450-112648
404632 9796668 Plus 45096-45229
404641 9796810 Minus 32247-32362
404642 9796810 Plus 102999-103145
405523 9454643 Plus 114550-114688,117265-117407,119490-119599,123237-123395,131140-131217
405558 1621110 Plus 4502-4644,5983-6083
Table 61 A lists about 440 genes up-regulated in prostate cancer compared to normal prostate and normal adult fiεεueε Theεe were εelxted from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" prostate cancer to "average" normal prostate tissue was greater than or equal to 20 and the ratio to normal adult tissues was greater than or equal to 20 The "average" prostate cancer level was εet to the 75* percentile amongεt proεtate cancerε The "average" normal proεtate tiεsue level was εet to the 95* percentile amongεt prostate tissues The "average" normal adult tissue level was set to the 85* percentile amongst non-malignant tissueε In order to remove gene- εpecific bxkground levelε of non specific hybridization, the 10* percentile value amongst the non-malignant tissues was subtracted from both the numerator and the denominator before the ratio was evaluated
TABLE 61A ABOUT 440 GENES UP-REGULATED IN PROSTATE CANCER COMPARED TO NORMAL PROSTATE AND NORMAL ADULT TISSUES Pkey Unique Eos probeset identifier number
ExAccn Exemplar Axession number, Genbank xcession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of prostate tumor to normal adult body fiεεue R2 Ratio of prostate tumor to normal prostate tiεεue
Pkey ExAccn UnigenelD Unigene Title R1 R2
444151 AW972917 Hs 128749 alpha-methylxyl-CoA rxemase 422 422
421566 NM 000399 Hs 1395 eariy growth response 2 (Krox-20 (Drosop 32 265
420729 AW964897 Hs 290825 ESTs 37 158
401197 ENSP00000229263ΗSPC213 30 126
450096 AI682088 Hs 79375 holxarboxylase synthetase (biotιn-[prop 124 124
449156 AF103907 Hs 171353 prostate cancer antigen 3, non-coding DD 123 123
443271 BE568568 Hs 195704 ESTs 11 6 11 6
434078 AW880709 Hs 283683 chromosome 8 open reading frame 4 21 11 2
431117 AF003522 Hs 250500 delta (Drosophιla)-lιke 1 94 94
417315 AI080042 Hs 180450 πbosomal protein S24 23 90
416182 NM 004354 Hs 79069 cyclin G2 84 84
421913 AI934365 Hs 109439 osteoglycin (oεteoinductive fxtor, mime 22 84
434217 AW014795 Hs 23349 ESTs 83 83
425782 U66468 Hs 159525 cell growth regulatory with EF-hand doma 83 83
442501 AA315267 Hs 23128 ESTs 20 83
429984 AL050102 Hs 227209 hypothetical protein FU21617 81 81
449048 Z45051 Hs 22920 similarto S68401 (cattle) glucose indue 31 80
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 340 79
420120 AL049610 Hs 95243 transcnption elongation fxtor A (Sll)- 75 75
419078 M93119 Hs 89584 msulinoma assxiated 1 74 74
425905 AB032959 Hs 318584 novel C3HC4 type Zinc finger (nng tinge 94 73
425018 BE245277 Hs 154196 E4F transcnption fxtor 1 72 72
452221 C21322 Hs 288057 hypothetical protein FLJ22242 70 70
421552 AF026692 Hs 105700 secreted fnzzled-related protein 4 40 66
409799 D11928 Hs 76845 phosphoseπne phosphatase-like 63 63
411373 BE326276 Hs 8861 ESTs 32 63
423445 NM 014324 Hs 128749 alpha-methylacyl-CoA rxemase 67 62
422583 AA410506 Hs 27973 KIAA0874 protein 23 62
438209 AL120659 Hs 6111 aryl-hydrocarbon receptor nuclear transi 6 1 61
437147 AL049964 Hs 8358 hypothetical protein FU20366 26 60 432415 T16971 Hs 289014 ESTs, Weakly similar to A43932 mucin 2 p 60 60
446896 T15767 Hs 22452 Homo sapienε mRNA for KIAA1737 protein 62 60
449118 R67477 Hs 23103 Bet1 (S cereviεiae) homolog 59 59
427472 AA522539 Hs 131250 traπsposon-deπved Buster3 traπεpoεaεe I 33 59
431548 AI834273 Hs 9711 novel protein 157 58
417153 X57010 Hs 81343 collagen, type II alpha 1 (primary oεte 42 58
410889 X91662 Hs 66744 twist (Drosophila) homolog (xrxephalos 35 58
429597 NM.003816 Hs 2442 a disintegnn and metalloprotemase doma 79 58
422538 NM 006441 Hs 118131 5,10 methenyltetrahydrofolate synthetase 57 57
414812 X72755 Hs 77367 monokine induced by gamma interferon 25 56
448552 AW973653 Hs 20104 hypothetical protein FLJ00052 56 56
416111 AA033813 Hs 79018 chromatin assembly factor 1 subunit A ( 55 55
414516 AI307802 Hs 135560 ESTs, Weakly similar to T43458 hypotheti 27 55
414343 AL036166 Hs 323378 coated veεicle membrane protein 54 54
451684 AF216751 Hs 26813 CDA14 39 54
421470 R27496 Hs 1378 annexm A3 53 53
426350 NM 003245 Hs 2022 transglutaminase 3 (E polypeptide, prote 53 53
436476 AA326108 Hs 33829 bHLH protein DEG2 28 53
437571 AA760894 Hs 153023 ESTs 52 52
447072 D61594 Hs 17279 tyrosylprotein sulfotransferase 1 52 52
444917 R68651 Hs 144997 ESTs 51 5 1
417318 AW953937 Hs 240845 ESTs 46 51
434170 AA626509 Hs 122329 ESTs 51 50
432897 AF155099 Hs 279780 NY-REN-18 antigen 33 50
433560 AI925195 Hs 130891 hypothetical protein MGC4400 48 50
421823 N40850 Hs 28625 ESTs 50 50
451244 AW008798 Hs 343877 hypothetical protein FLJ 20039 49 49
453370 AI470523 Hs 139336 ATP-bindmg cassette, sub-family C (CFTR 298 49
425242 D13635 Hs 155287 KIAA0010 gene product 22 48
439024 R96696 Hs 35598 ESTs 54 48
407235 D20569 Hs 169407 SAC2 (suppressor of actin mutations 2, y 48 48
421863 AI952677 Hs 108972 Homo sapiens mRNA, cDNA DKFZp434P228 (fr 47 47
437916 BE566249 Hs 20999 hypothetical protein FLJ23142 36 47
451952 AL120173 Hs 301663 ESTs 47 47
431676 AI685464 gb tt88f04 x1 NCI_CGAP_Pr28 Homo sapiens 91 47
452242 R50956 Hs 159993 gycosyltransferase 47 47
401519 C15000476* gι|12737279|ref|XP_012163 1| 46 46
414342 AA742181 Hs 75912 KIAA0257 protein 34 46
426197 AA004410 Hs 100009 acyl-Coenzyme A oxidase 1, palmitoyi 33 46
429467 NM 004477 Hs 203772 FSHD region gene 1 2 1 46
408380 AF123050 Hs 44532 diubiquitm 42 46
425907 AA365752 Hs 155965 ESTs 22 46
427078 AI676062 Hs 111902 ESTs 48 45
419465 AW500239 Hs 21187 Homo sapienε cDNA FU23068 fis clone L 27 45
429250 H56585 Hs 198308 tryptophan rich basic protein 45 45
431585 BE242803 Hs 262823 hypothetical protein FLJ10326 25 45
443250 A1041530 Hs 132107 ESTs 8 1 44
423545 AP000692 Hs 129781 chromosome 21 open reading frame 5 44 44
423698 AA329796 Hs 1098 DKFZp434J1813 protein 44 44
442281 N34742 Hs 170065 Homo sapiens cDNA FU13492 fis, clone PL 44 44
428826 AL048842 Hs 194019 attrxtin 20 43
447188 H65423 Hs 17631 hypothetical protein DKFZp434E2135 43 43
418701 AA814948 Hs 96343 ESTs, Weakly similar to ALUC HUMAN "" 42 42
429900 AA460421 Hs 30875 ESTs 42 42
439518 W76326 gb zd60d04 r1 Soares_fetal_heart_NbHH19W 22 42
409151 AA306105 Hs 50785 SEC22, veεicle trafficking protein (S c 35 42
420544 AA677577 Hs 98732 Homo sapiens Chromosome 16 BAC clone CIT 100 42
444100 AA383343 Hs 22116 CDC14 (cell division cycle 14, S cerevi 28 42
443622 AI911527 Hs 11805 ESTs 22 41
410037 AB020725 Hs 58009 KIAA0918 protein 41 41
421129 BE439899 Hs 89271 ESTs 41 41
428966 AF059214 Hs 194687 cholesterol 25-hydroxylase 39 41
448664 AI879317 Hs 334691 splicing fxtor 3a, subunit 1, 120kD 28 41
432242 AW022715 Hs 162160 ESTs, Weakly similar to ALU4 HUMAN ALU S 20 41
433887 AW204232 Hs 279522 ESTs 41 41
436556 AI364997 Hs 7572 ESTs 41 41
400301 X03635 Hs 1657 estrogen rxeptor 1 4 1 41
443646 AI085198 Hs 164226 ESTs 41 41
430389 AL117429 Hs 240845 DKFZP434D146 protein 22 40
418432 M14156 Hs 85112 insulin-like growth factor 1 (somatomedi 40 40
433409 AI278802 Hs 25661 ESTs 40 40
447247 AW369351 Hs 287955 Homo sapienε cDNA FLJ 13090 fiε, clone NT 40 40
423749 U09848 Hs 132390 zinc finger protein 36 (KOX 18) 39 39
444755 AA431791 Hs 113823 ClpX (caseinolytic protease X, E coli) 39 39
431912 AI660552 Hs 76549 ESTs, Weakly similar to A56154 Abl subst 22 39
428493 AK001745 Hs 184628 hypothetical protein FLJ10883 33 39
447482 AB033059 Hs 18705 KIAA1233 protein 22 39
450203 AF097994 Hs 301528 L-kynurenme/alpha ammoadipate ammotra 39 39
423337 NM 004655 Hs 127337 axm 2 (conductm, axil) 34 38
452588 AA889120 Hs 110637 homx box A10 65 38
422661 NM 014700 Hs 119004 KIAA0665 gene product 38 38
407317 AI204033 Hs 271461 ESTs, Weakly similar to I38022 hypotheti 23 38
410330 AW023630 Hs 159425 ESTε 62 38 422975 AA347720 Hs 122669 KIAA0264 protein 22 38
425878 AW964806 Hs 38085 Homo sapienε, Similar to RIKEN cDNA 0610 38 38
414664 AA587775 Hs 66295 multi PDZ-domain-containmg protein 38 38
437162 AW005505 Hs 5464 thyroid hormone receptor coxtivatmg pr 27 38
421828 AW891965 Hs 279789 hiεtone dexetylaεe 3 41 38
418821 AA436002 Hs 183161 ESTε 28 38
422049 W25760 Hs 77631 glycine cleavage εyεtem protein H (ammo 31 38
453160 AI263307 Hs 239884 H2B histone family, member L 92 38
424906 AI566086 Hs 153716 Homo εapiens mRNA for Hmob33 protein 3' 37 37
446554 AA151730 Hs 301789 nudix (nucleoside diphosphate linked mol 37 37
452259 AA317439 Hs 28707 signal sequence receptor, gamma (translo 37 37
448807 AI571940 Hs 7549 ESTε 36 37
439209 AF087993 Hs 91954 ESTε 2 1 36
420077 AW512260 Hs 87767 ESTε 44 36
451009 AA013140 Hs 115707 ESTε 4 1 36
452281 T93500 Hs 28792 Homo εapienε cDNA FLJ 11041 fis clone PL 36 36
452561 AI692181 Hs 49169 KIAA1634 protein 32 36
447033 AI357412 Hs 157601 ESTs 77 36
427138 N77624 Hs 173717 phosphatidic acid phosphatase type 2B 36 36
442991 BE281238 Hs 8886 hypothetical protein FLJ20424 36 36
414680 AA743331 hemoglobin, alpha 2 35 35
417380 T06809 Hs 332086 ESTs 35 35
425710 AF030880 Hs 159275 solute camerfamily, member 4 35 35
441247 AW118681 Hs 128051 Homo sapienε thymic stromal lymphopoiefi 35 35
426931 NM 003416 Hs 2076 zinc finger protein 7 (KOX 4 clone HF 1 22 35
417873 BE266659 Hs 293659 Homo sapiens, Similar to RIKEN cDNA A430 35 35
432101 AI918950 Hs 123642 EphA3 165 35
429302 AU076674 Hε 198899 eukaryotic translation initiation factor 33 35
435513 AW404075 Hs 42785 DC11 protem 22 35
440643 M78878 Hs 7314 KIAA0614 protein 21 35
418293 AI224483 Hs 16063 hypothetical protein FLJ21877 67 34
425900 AK000166 Hs 288809 hypothetical protem FLJ20159 2 1 34
431689 AA305688 Hs 267695 UDP-Gal betaGIcNAc beta 1,3-galactoεyltr 2 1 34
440749 W22335 Hs 7392 hypothetical protein MGC3199 25 33
408374 AW025430 Hs 155591 foΛhead box F1 43 33
400277 Eoε Control 24 33
432169 Y00971 Hs 2910 phosphoπbosyl pyrophosphate εynthetase 33 33
437872 AK002015 Hs 5887 RNA binding motif protein 7 33 33
443912 R37257 Hs 184780 ESTε 33 33
414565 AA502972 Hs 183390 hypothetical protein FLJ 13590 99 33
448164 R61680 Hs 26904 ESTε, Moderately similar to Z195.HUMAN Z 33 33
450094 AI174947 Hs 295789 Homo sapienε mRNA, cDNA DKFZp564D1164 (f 44 33
424800 AL035588 Hs 153203 MyoD family inhibitor 36 33
451367 AA923729 Hs 26322 cell cycle related kinase 33 32
445472 AB006631 Hs 12784 Homo sapiens mRNA for KIAA0293 gene, par 11 5 32
408101 AW968504 Hs 123073 CDG2-related protein kinase 7 20 32
421246 AW582962 Hs 102897 CGI-47 protein 32 32
426227 U67058 Hs 154299 Human proteinase xtivated rxeptor-2 mR 32 32
402802 NM.001397 Homo sapiens endothelin conver 43 32
419168 AI336132 Hs 33718 Homo sapiens cDNA FLJ 12641 fis, clone NT 27 32
436207 AA334774 Hs 12845 hypothetical protein MGC13159 32 32
453864 AW021407 Hs 21068 hypothetical protein 32 32
448944 AB014605 Hs 22599 atrophιn-1 interxting protein 1, xtivi 38 32
444489 AI151010 Hs 157774 ESTs 32 32
453124 AI139058 Hs 125790 leucine πch repeat-containing 2 32 32
453078 AF053551 Hs 31584 metaxin 2 2 1 31
439444 AI277652 Hs 54578 ESTε, Weakly similar to I38022 hypotheti 106 31
413492 D87470 Hs 75400 KIAA0280 protein 28 3 1
434804 AA649530 Hε 348148 gb ns44f05 ε1 NCI CGAP_Alv1 Homo εapiens 21 31
445840 AI277811 Hs 146291 ESTs 3 1 31
423566 AW976434 Hs 3623 hypothetical protein FLJ 11220 22 31
408161 AW952912 Hε 300383 hypothetical protein MGC3032 31 3 1
414922 D00723 Hε 77631 glycine cleavage syεtem protein H (ammo 3 1 31
430519 AF129534 Hε 49210 F-box only protein 4 3 1 31
430487 D87742 Hs 241552 KIAA0268 protem 162 31
423554 M90516 Hs 1674 glutamine-fructoεe 6-phoεphate transamm 3 1 31
430226 BE245562 Hs 2551 adrenergic, beta-2-, rxeptor, surface 90 31
400296 AA305627 Hs 139336 ATP-bindmg cassette, sub-family C (CFTR 209 3 1
420154 AI093155 Hs 95420 JM27 protein 274 31
453293 AA382267 Hs 10653 ESTs 37 31
457718 F18572 Hs 22978 ESTs, Weakly similar to ALU4_HUMAN ALU S 30 30
447476 BE293466 Hs 20880 ESTs, Weakly similar to I38022 hypotheti 24 30
419440 AB020689 Hs 90419 KIAA0882 protein 29 30
433285 AW975944 Hs 237396 ESTs 77 30
450671 AI356967 Hs 43086 ESTs, Weakly similar to A46010 X-lmked 30 30
445921 AW015211 Hs 146181 ESTs 43 30
416882 AI633044 tryptophanyl tRNA synthetaεe 2 (mitxhon 35 30
414052 AW578849 Hs 283552 ESTε, Weakly similar to unnamed protein 25 30
450580 N40087 ESTs 30 30
447726 AL137638 Hs 19368 matπlin 2 39 29
447816 NM 007233 Hs 274329 TP53 target gene 1 72 29
420407 AA814732 Hs 145010 lipopolysaccaπde-specific response 5-lι 5 1 29
422299 AK000181 Hs 114556 hypothetical protein FLJ20174 26 29 420297 AI628272 Hε 88323 ESTs Weakly similarto ALULHUMAN ALU S 29 29
427701 AA411101 Hε 243886 nuclear autoantigenio sperm protein (his 29 29
437812 AI582291 Hε 16846 ESTs, Weakly similar to 04HUD1 debπsoqu 29 29
445808 AV655234 ESTs Moderately similar to PC4259 fern 29 29
428600 AW863261 Hε 242413 hypothetical protein DKFZp434K1421 47 29
442320 AI287817 Hs 129636 ESTs 37 29
418407 AL044818 Hs 84928 nuclear transcription factor Y, beta 24 29
433050 AI093930 Hs 163440 Homo sapiens cDNA FLJ21000 fis, clone C 29 29
451796 AL133019 Hε 27038 Homo sapiens mRNA, cDNA DKFZp434G2127 (f 29 29
407783 AW996872 Hs 172028 a disintegnn and metalloprotemase doma 30 29
459029 AA131376 Hs 343809 fibroblast growth factor 12B 29 29
441676 BE564206 Hs 49889 ESTs 44 29
439352 BE614347 Hs 169615 hypothetical protein FU20989 21 29
453628 AW243307 Hs 83937 hypothetical protein 29 29
412324 AW978439 Hs 69504 ESTs 20 28
408063 BE086548 Hs 42346 calcineuπn binding protein calsarcιn-1 50 28
421928 AF013758 Hs 109643 polyadenylate binding protein mteractin 64 28
421247 BE391727 Hs 102910 general transcription factor HH polype 28 28
433865 N29862 Hs44104 ESTs 28 28
423201 NM 000163 Hs 125180 growth hormone receptor 63 28
450832 AW970602 Hs 105421 ESTs 2 1 28
416913 AW934714 gb RC1-DT0001-031299 011-a11 DT0001 Homo 28 28
417251 AW015242 Hs 99488 ESTs, Weakly similar to YK54_YEAST HYPOT 28 28
427144 X95097 Hs 2126 vasoactive intestinal peptide rxeptor 2 28 28
444668 AA654650 Hs 282906 ESTs 22 28
434015 AA844518 Hs 300876 hypothetical protein FLJ 13386 32 28
432689 AB018320 Arg/Abl interacting protein ArgBP2 21 28
423482 BE280172 Hs 129228 galactokinase 2 24 28
448206 BE622585 Hs 3731 ESTs, Moderately similar to 138022 hypot 28 28
450546 AA010200 Hs 175551 ESTs 22 27
452270 AW975014 Hs 26 ferrochelatase (protoporphyπa) 36 27
458332 AI000341 Hs 220491 ESTs 49 27
436109 AA922153 Hs 132760 hypothetical protein MGC15729 27 27
422867 L32137 Hs 1584 cartilage oligomeπc matrix protein (pse 2 1 27
412576 AA447718 Hε 107057 ESTs 27 27
413336 AI569936 Hs 296178 hypothetical protein FLJ22637 27 27
433577 AW007080 Hs 284192 ESTs 27 27
439093 AA534163 Hs 5476 Homo sapiens, clone IMAGE 3530123, mRNA, 27 27
442833 AA328153 Hs 88201 ESTs, Weakly similar to A Cham A Cryst 27 27
447401 BE618582 Hε 97661 ESTε 27 27
409619 AK001015 Hs 55220 BCL2-assxιated athanogene 2 27 27
432729 AK000292 Hs 130732 hypothetical protein FLJ 20285 22 27
452721 AJ269529 Hs 301871 solute carrier family 37 (glycerol-3-pho 32 27
447342 AI199268 Hs 19322 Homo sapiens, Similar to RIKEN cDNA 2010 90 27
409205 AI952884 Hs 14832 ESTs, Moderately similar to unnamed prot 24 27
422805 AA436989 Hs 121017 H2A histone family, member A 13 6 27
446238 T95143 Hs 14511 SCO (cytxhrome oxidase deficient, yeast 21 27
447313 U92981 Hs 18081 Homo sapiens clone DT1P1B6 mRNA CAG rep 8 1 27
411630 U42349 Hs 71119 Putative prostate cancer tumor suppresso 62 26
410592 R94088 Hs 43569 ESTs 26 26
417173 U61397 Hs 81424 ubiquitin like 1 (sentπn) 26 26
417601 NM 014735 Hs 82292 KIAA0215 gene product 26 26
433419 AI830342 Hs 211272 ESTs 29 26
447509 AF107454 Hs 107537 chromosome 7 open reading frame 2 20 26
424580 AA446539 Hs 339024 ESTs, Weakly similar to A46010 X-linked 24 26
407252 AA659037 Hs 163780 ESTs 26 26
420061 AW024937 Hs 29410 ESTs 24 26
424432 AB037821 Hs 146858 protocadhenn 10 79 26
417683 AW566008 Hs 239154 ankyπn repeat, family A (RFXANK-like), 27 26
414312 AA155694 Hs 191060 ESTs 26 26
417135 AA422067 Hs 50547 ESTs 26 26
437748 AF234882 Hs 5814 suppreεεion of tumoπgemcity 7 26 26
422728 AW937826 Hε 103262 ESTε, Weakly similar to ZN91JHUMAN ZINC 90 26
453070 AK001465 Hs 31575 SEC63, endoplasmic reticulum translxon 22 26
406627 T64904 Hs 163780 ESTε 87 26
407151 H25836 Hs 301527 ESTε, Moderately similar to unknown [H s 24 26
425815 R94023 Hs 94560 ESTs, Moderately similar to I38022 hypot 26 26
433805 AA706910 Hs 112742 ESTs 26 26
431474 AL133990 Hs 190642 ESTs 93 25
436204 AK002014 Hs 47546 Homo sapienε cDNA FLJ11458 fiε, clone HE 22 25
439328 W07411 Hε 118212 ESTε, Moderately similar to ALU3 HUMAN A 33 25
449115 AW959952 Hs 37528 ESTs, Weakly similar to AF0909441 PRO06 23 25
437531 AI400752 Hs 112259 T cell rxeptor gamma Ixus 26 25
445424 AB028945 Hs 12696 cortxtin SH3 domain binding protein 34 25
403047 NM_005656* Homo sapiens transmembrane pr 21 1 25
416198 H27332 Hs 99598 hypothetical protein MGC5338 25 25
417576 AA339449 Hs 82285 phosphoribosylglycmamide formyltransfer 25 25
430607 AW973521 Hs 247324 mitochondnal πbosomal protein S14 25 25
436401 AI087958 Hs 29088 ESTs 25 25
450654 AJ245587 Hs 25275 Kruppel type zinc finger protein 25 25
426216 N77630 Hs 13895 Homo sapienε cDNA FLJ 11654 fis, clone HE 30 25
431325 AW026751 Hs 5794 ESTs, Weakly similar to 2109260A B cell 11 9 25
410102 AW248508 Hs 279727 Homo sapiens cDNA FLJ14035 fis, clone HE 25 25 446791 AI632278 Hs 195922 ESTs 25 25
418004 U37519 Hs 87539 aldehyde dehydrogenase 3 family, member 25 25
419791 AI579909 Hs 105104 ESTs 27 25
447210 AF035269 Hs 17752 phosphatidylseπne specific phospholipas 30 25
425294 AF033827 Hs 155553 HNK 1 εulfotransferase 21 25
452741 BE392914 Hs 30503 Homo εapienε cDNA FLJ11344 fis, clone PL 25 25
447702 AI420256 Hs 161271 ESTs 2 1 24
412043 BE156622 Hs 333371 Homo sapiens clone TA40 untranslated mRN 24 24
421413 AI826128 Hs 57637 ESTs, Weakly similar to A4936459 protei 24 24
429128 AA446869 Hs 119316 ESTs 20 24
429258 AA448765 gb zx10e09 r1 Soares_total_fetuε_Nb2HF8_ 24 24
435102 AW899053 Hε 76917 F-box only protein 8 24 24
456161 BE264645 Hs 282093 hypothetical protein FLJ21918 31 24
407021 U52077 gb Human maπnerl transposase gene, comp 73 24
437517 AI927675 Hs 244482 Homo sapiens, clone IMAGE 3611719 mRNA, 2 1 24
408267 AW380525 Hs 343564 tubulin-specific chaperone e 43 24
447713 AI420733 Hs 207083 ESTε 24 24
456848 AL121087 Hs 296406 KIAA0685 gene product 22 24
437617 AI026701 Hs 5716 KIAA0310 gene product 26 24
432378 AI493046 Hs 146133 ESTε 52 24
443180 R15875 Hs 258576 claudin 12 10 1 24
445929 AI089660 Hs 323401 dpy-30 like protein 22 24
424701 NM 005923 Hs 151988 mitogen-activated protein kinase kinase 23 24
445255 NM 014841 Hs 12477 synaptosomal assxiated protein, 91 kDa 25 24
409731 AA125985 Hε 56145 thymosin, beta, identified in neuroblaεt 27 5 24
421709 AA159394 Hs 107056 CED 6 protein 23 24
412707 AW206373 Hs 16443 Homo εapienε cDNA FLJ21721 fiε, clone C 47 24
418882 NM 004996 Hs 89433 ATP-binding cassette sub-family C (CFTR 24 24
451071 AW138807 Hs 204939 ESTε, Highly εimilar to A54677 homeotic 24 24
420344 BE463721 Hs 97101 putative G protein-coupled rxeptor 3 1 23
433037 NM 014158 Hs 279938 HSPC067 protein 24 23
418329 AW247430 Hs 84152 cystathioπine beta synthase 41 23
419544 AI909154 gb QV-BT200-010499 007 BT200 Homo sapien 23 23
424602 AK002055 Hs 151046 hypothetical protein FU11193 2 1 23
450693 AW450461 Hs 203965 ESTs 23 23
452387 AI680772 Hs 306094 tπnucleotide repeat containing 12 23 23
412045 AA099802 Hs 83883 tranεmembrane proεtate androgen induced 41 23
428180 AI129767 Hs 182874 guanine nucleotide binding protein (G pr 20 23
419438 AA406400 Hs 12482 glyceronephoεphate O acyltranεferase 27 23
443194 AI954968 Hs 279009 matrix Gla protein 2 1 23
414869 AA157291 Hs 21479 ubiπuclein 1 25 23
407300 AA102616 Hs 120769 gb zn43e07 s1 Stratagene HeLa cell ε393 23 23
436396 AI683487 Hs 152213 wingless type MMTV integration site fami 23 23
439221 AA737106 Hs 32250 ESTs, Moderately similarto I78885 seππ 23 23
453802 AL134757 gb DKFZp547G1090_r1 547 (synonym hfbrl) 4 1 23
421059 A1654133 Hs 30212 thyroid rxeptor interacting protein 15 79 23
426413 AA377823 gb EST90805 Synovial sarcoma Homo sapien 22 23
431147 AI767751 Hs 20300 ESTs 58 23
442677 AI557914 peroxisomal xyl CoA thioeεteraεe 25 23
446091 AW022192 Hs 200197 ESTε 40 23
431563 AI027643 Hs 120912 ESTε 22 23
439478 AF049460 Hs 6574 deformed epidermal autoregulatory fxtor 21 23
413049 NM.002151 Hs 823 hepεin (transmembrane protease, seπne 1 35 23
405685 C2002829 gιl4507689|reflNP_003298 1| tra 23 23
407917 U63139 Hs 41587 RAD50 (S cerevisiae) homolog 23 23
450378 AW249181 Hs 19954 ESTs, Weakly similar to T19873 hypotheti 23 23
429303 AW137635 Hs 44238 ESTs, Weakly similar to S65657 alpha-1 C- 23 23
417248 AA329449 Hs 247302 twisted gastrulation 23 22
429277 AW452016 Hs 127863 ESTs, Weakly similar to SFR4_HUMAN SPLIC 26 22
431555 AI815470 Hε 260024 Cdc42 effector protein 3 45 22
440099 AL080058 Hs 6909 DKFZP564G202 protein 29 22
416653 AA768553 Hs 193145 metallothionem 1E (functional) 34 22
431542 H63010 Hs 5740 ESTs 70 22
401558 ENSP00000220478* SECRETOGRANIN III 22 22
418281 U09550 Hs 1154 oviductal glycoprotein 1, 120kD (mucin 9 22 22
422295 AF051151 Hs 114408 toll-like receptor 5 22 22
432453 AI885537 Hs 27172 ESTs, Moderately similar to PC4259 fern 22 22
447499 AW262580 Hs 147674 protocadhenn beta 16 22 22
452994 AW962597 Hs 31305 KIAA1547 protein 40 22
450325 AI935962 Hs 26289 ESTs 11 9 22
422390 AW450893 Hs 121830 ESTs, Weakly similar to T42682 hypotheti 2 1 22
448789 BE539108 Hs 22051 hypothetical protein MGC15548 26 22
436679 AI127483 Hs 120451 ESTs, Weakly similar to unnamed protein 11 8 22
425263 NM 001197 Hs 155419 BCL2 interacting killer (apoptosis-induc 32 22
451939 U80456 Hs 27311 single minded (Drosophila) homolog 2 136 22
410252 AW821182 Hε 61418 microfibπllar assxiated protein 1 42 22
439699 AF086534 Hε 187561 ESTs, Moderately similar to ALU1.HUMAN A 48 22
422576 BE548555 Hε 118554 CGI 83 protein 2 1 22
433293 AF007835 Hs 32417 hypothetical protem MGC4309 11 0 22
410733 D84284 Hs 66052 CD38 antigen (p45) 31 22
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy 2 1 22
442995 AA532511 Hs 288455 Homo sapiens cDNA FLJ23270 fis, clone C 22 22
408833 AW612232 Hs 254835 ESTs 30 22 422424 AI186431 Hs 296638 prostate differentiation factor 44 22
433444 AW975324 Hs 129816 ESTs 11 7 22
446354 AW449650 Hs 346335 ESTs 26 22
438869 AF075009 gb Homo sapienε full length insert cDNA 59 22
425628 NM 004476 Hs 1915 folate hydrolase (prostate-εpecific memb 128 22
424036 AA770688 H2A histone family, member L 38 22
440146 AW014231 Hs 90790 Homo sapiens cDNA FLJ22930 fis clone K 48 22
404641 NM.021965* Homo sapiens phosphoglucomuta 22 22
407253 AA411175 Hs 141939 ESTs, Moderately similar to S65657 alpha 22 22
406068 C2002008 gι|7303957|gb|AAF59000 1| (AE00 31 2 1
415162 AF035718 Hs 78061 transcription factor 21 2 1 2 1
423349 AF010258 Hs 127428 homeo box A9 59 2 1
424534 D87682 Hs 150275 KIAA0241 protein 23 2 1
407756 AA116021 Hs 38260 ubiquitin specific protease 18 25 2 1
440658 H29142 Hs 143032 ESTs, Weakly similar to neuronal thread 25 2 1
416547 H62914 Hs 268946 ESTε, Weakly similar to PC4259 femtin 2 1 2 1
432281 AK001239 Hs 274263 hypothetical protem FLJ 10377 21 2 1
447533 NM 004786 Hs 18792 thioredoxin-like, 32kD 2 1 2 1
448966 AW372914 Hε 86149 phosphomositol 3-phosphate-bιndιng prot 21 2 1
449897 AW819642 Hε 24135 transmembrane protein vezatin, hypotheti 2 1 2 1
452959 AI933416 Hs 189674 ESTs 21 21
427083 NM 006363 Hs 173497 Sec23 (S cerevisiae) homolog B 28 2 1
408291 AB023191 Hs 44131 KIAA0974 protein 2 1 2 1
418727 AA227609 Hs 94834 ESTs 21 2 1
440491 R35252 Hs 130558 ESTs, Weakly similar to 2109260A B cell 21 2 1
433466 AA508353 Hs 105314 relaxm 1 (H1) 17 3 2 1
432695 D63480 Hs 278634 KIAA0146 protein 23 2 1
427982 NM 016156 Hs 181326 KIAA1073 protein 32 2 1
445873 AA250970 Hs 251946 poly(A) binding protein, cytoplasmic 1-1 25 2 1
434569 AI311295 Hs 344478 KIAA0196 gene product 2 1 21
441791 AW372449 Hs 61271 hypothetical protein FLJ21159 2 1 2 1
438520 AA706319 Hs 98416 ESTs 27 2 1
414269 AA298489 Hs 303171 olfactory rxeptor, family 51, εubfamily 173 2 1
410660 AI061118 Hs 65328 Fanconi anemia, complementation group F 35 2 1
456660 AA909249 Hs 112282 εolute carrier family 30 (zinc transport 74 2 1
450861 AI523898 Hs 17617 ESTs 24 2 1
419193 D29643 Hs 34789 dolichyl-diphosphooligoεacchande-protei 2 1 21
423784 AK000039 Hs 132826 Homo sapiens cDNA FLJ14913 fis, clone PL 32 2 1
416208 AW291168 Hs 41295 ESTs, Weakly similar to MUC2 HUMAN MUCIN 64 21
407182 AA312551 Hs 230157 ESTε 21 21
421689 N87820 Hs 106826 KIAA1696 protein 2 1 2 1
432833 N51075 Hs 110028 ESTε 21 2 1
425170 AU077315 Hs 154970 transcription factor CP2 26 20
436278 BE396290 Hs 5097 synaptogyπn 2 28 20
438719 AA357129 Hs 239625 integral membrane protein 2B 23 20
432728 NM 006979 Hs 278721 HLA class II region expresεed gene KE4 36 20
410310 J02931 Hs 62192 coagulation fxtor III (thromboplastin, 20 20
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 36 20
424081 NM 006413 Hs 139120 nbonuclease P (30kD) 20 20
433800 AI034361 Hs 135150 lung type-l cell membrane-assxiated gly 20 20
413627 BE182082 Hs 246973 ESTs 33 20
414133 AW022188 Hs 41167 ESTs 23 20
411096 U80034 Hε 68583 mitochondnal intermediate peptidase 147 20
450244 AA007534 Hs 125062 ESTs 31 20
422493 AW474183 Hs 250173 hypothetical protein FU13158 26 20
409219 AA393383 Hs 133331 ESTs 21 20
419986 AI345455 Hε 78915 GA-bindmg protein transcnption fxtor, 20 20
421969 AF052217 Hε 110099 core-binding fxtor, runt domain, alpha 20 20
434128 W93170 Hε 284164 protein x 0004 27 20
434503 T96231 Hε 17762 ESTs 20 20
443292 AK000213 Hε 9196 hypothetical protein 20 20
443555 N71710 Hs 21398 ESTε, Moderately similar to A Cham A, H 20 20
448172 N75276 Hs 135904 ESTs 60 20
452039 AI922988 Hs 172510 ESTs 20 20
400290 H18836 Hs 31608 hypothetical protein FLJ20041 62 20
449625 NM 014253 odz (odd Oz/ten-m, Drosophila) homolog 1 101 20
441406 Z45957 Hs 7837 phosphoprotem regulated by mitogenic pa 23 20
451369 AA017321 Hs 269691 ESTs 21 20
434011 AW953437 Hs 5486 clone FLB5214 21 20
408806 AW847814 Hε 289005 Homo sapienε cDNA FLJ21532 fis, clone C 54 20
433388 AI432672 Hs 288539 hypothetical protein FLJ22191 27 20
432653 N62096 Hs 293185 ESTε, Weakly similar to JC7328 ammo xi 55 20
446783 AW138343 Hs 141867 ESTs 44 20
437323 AA371145 Hs 194397 leptin rxeptor 25 20
410076 T05387 Hs 7991 ESTs 29 20
421501 M29971 Hs 1384 0-6-methylguaπme-DNA methyltransferase 21 20
419733 AW362955 Homo sapiens cDNA FLJ14415 fis, clone HE 25 20
TABLE 61B Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Accesεion Genbank xcession numbers
Pkey CAT Number Accesεion 414680 147525.1 AA743331 AA837388 AW664540 AA775711 AA150965 BE465475 AA968994 AA886905 AI141054 AW194991 AA252147 AA319500 AI184288
AA708749 AA644620 AA652769 AA242975 AA151074 T19890
416882 162718.1 AI633044 AW016212 AW241143 AA769058 R43272 AW068958 AA210918 AA293774 AI748815 AI763294 AI333114 AI277384 AI088297 AI468477
AI824624 AW189606 AI631751 Z40749 AI984673 AI671316 AA189024 AW235412 BE1784
416913 163001 1 AW934714 BE161007 BE162500 AW749902 AW749864 BE162498 BE161005 AA190449 AW513465 BE161006 BE162499 419544 185760 2 AI909154 AA526337 AA244193 AI909153 419733 187589.1 AW362955 H59488 AI040666 W60959 W94209 H27231 T84625 H75715 W04957 W63676 AA659693 AA514302 W63789 BE046412T91396
AI951970 AW044233 N20018 AW663548 T90114 AI139947 AA809643 AA846232 AA581966 AA789002
424036 23460.1 AA770688 H15373 AW161070 BE304523 BE378517 AA989300 AA904029 BE254211 AA449148 AI268420 AI300495 AI215637 AI300494 AI268551
AA928971 AA179427 AA947684 BE393792 H98018 AI885781 AI188567 AI290658 C15404
426413 266650 1 AA377823 AW954494 AI022688 429258 301917.1 AA448765 C04967 C03045 AA658293 431676 336411 1 AI685464 AW971336 AA513587 AA525142 432689 35275.1 AB018320 H56457 AA247916 N83488 N87920 AA095653T19858 AL134279 AA094167 AI673378 AI000340 R47500 W16595 AW152297 AI625937
AA002027 AI814851 AA902666 AI039729 AW975053 BE302243 AI240793 AA193203 N5581
438869 46651 1 AF075009 R63109 R63068 439518 47334 1 W76326 AF086341 W72300 442677 548626.1 AI557914 W81031 AW473764 AI814081 W81068 AW182826 AW173296 AI376594 AI220500 BE257195 BE246486 R55637 C20788 AI014407
AI248353 AW028015
445808 65133 1 AV655234 AW966332 AA340239 449625 8113.T NM.014253 AF100772 BE088769 AL022718 BE161779AW863569 BE161640 AL039060 BE168542AW296554AA323193 AA235370 AW779760
N48674 AI375997 R45432 D59344 AI203107 F07491 R35360 R25094 AI913631 AI498402 T613
450580 83929.1 N40087 H12925 AA460779 AA096372 BE160847 AW816890 AW816893 AW816577 AW816891 AW816882 AW816868 AW816889 AW816940
AW816892 AW816941 AW816578 AA029183 T83320 H86850 AA010295 BE160823 Z25353 AA150883 AW8
453802 981589.1 AL134757 AW079131
TABLE 61 C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA εequence of human chromoεome 22 " Dunham I et al . Nature (1999) 402489 495
Strand Indicates DNA strand from which exonε were predicted
Nt position Indicates nucleotide positions of predicted exons
Pkey Ref Strand Nt position
401197 9719705 Plus 176341-176452
401519 6649315 Plus 157315-157950
401558 7139678 Plus 103510-104090
402802 3287156 Minus 53242-53432
403047 3540153 Minus 59793-59968
404641 9796810 Minus 32247-32362
405685 4508129 Minus 37956-38097
406068 9114084 Plus 382-543
Table 62A lists about 600 genes up-regulated in prostate cancer compared to normal adult tisεueε These were εelxted from 59680 probeεetε on the Affymetπx/Eoε Hu03 GeneChip array εuch that the ratio of "average" prostate cancer to "average" normal adult tisεueε was greater than or equal to 30 The "average" prostate cancer level was set to the 75* percentile amongst prostate cancers The "average" normal prostate tisεue level was set to the 95* percentile amongst normal prostate tissues In order to remove gene-specific bxkground levels of non-spxific hybridization, the 10* percenfile value amongεt non malignant body tiεεues was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 62A ABOUT 600 GENES UP-REGULATED IN PROSTATE CANCER COMPARED TO NORMAL PROSTATE TISSUES
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accesεion number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of proεtate tumor to normal prostate tisεue
Pkey ExAccn UnigenelD Unigene Title R1
444151 AW972917 Hε 128749 alpha-methylxyl-CoA rxemase 422
421566 NM 000399 Hs 1395 early growth response 2 (Krox-20 (Drosop 265
427274 NM 005211 Hs 174142 colony stimulating factor 1 rxeptor, fo 160
420729 AW964897 Hs 290825 ESTε 158
412326 R07566 Hε 73817 small inducible cytokine A3 (homologous 147
416188 BE157260 Hε 79070 v myc avian myelxytomatosis viral oncog 136
417696 BE241624 Hs 82401 CD69 antigen (p60 eariy T-cell activati 13 1
424247 X14008 Hε 234734 lysozyme (renal amyloidosis) 126
401197 ENSP00000229263* HSPC213 126
426793 X89887 Hε 172350 HIR (histone cell cycle regulation defec 126
450096 AI682088 Hε 79375 holocarboxylase synthetaεe (biotin [prop 124
449156 AF103907 Hs 171353 proεtate cancer antigen 3, non-coding DD 123
443271 BE568568 Hs 195704 ESTs 11 6
434078 AW880709 Hs 283683 chromosome 8 open reading frame 4 11 2
423396 AI382555 Hs 127950 bromodomain containing 1 11 2 406038 Y14443 zinc finger protein 200 11 1
426559 AB001914 Hs 170414 paired basic ammo acid cleaving system 106
419553 N34145 Hs 10177 ESTs, Moderately similar to ZN91.HUMAN Z 104
418036 Z37976 Hs 83337 latent transforming growth factor beta b 10 3
410023 AB017169 Hs 57929 slit (Drosophila) homolog 3 101
421684 BE281591 Hs 106768 hypothetical protein FLJ10511 99
426490 NM.001621 Hs 170087 aryl hydrocarbon receptor 99
437866 AA156781 metallothioπein 1E (functional) 95
440274 R24595 Hs 7122 scrapie responsive protein 1 94
431117 AF003522 Hs 250500 delta (Drosophila) like 1 94
405141 Y14443 zinc finger protein 200 92
448520 AB002367 Hs 21355 doublxortin and CaM kinase like 1 92
417315 AI080042 Hs 180450 πbosomal protein S24 90
433332 AI367347 Hs 44898 Homo sapiens clone TCCCTA00151 mRNA sequ 90
456614 AV653110 Hs 106650 hypothetical protein FLJ20533 89
427019 AA001732 Hs 173233 hypothetical protein FU 10970 89
432606 NM 002104 Hs 3066 granzyme K (seπne protease, granzyme 3, 88
417381 AF164142 Hs 82042 solute earner family 23 (nucleobase tra 86
425174 D87450 Hs 154978 KIAA0261 protein 86
445701 AF055581 Hs 13131 lymphocyte adaptor protein 85
416182 NM 004354 Hs 79069 cyclin G2 84
445230 U97018 Hs 12451 echinoder microtubule associated protei 84
421913 AI934365 Hs 109439 osteoglycin (osteo ductive factor, mime 84
434217 AW014795 Hs 23349 ESTs 83
417363 AW129357 Hs 329700 ESTs 83
425782 U66468 Hs 159525 cell growth regulatory with EF-hand doma 83
442501 AA315267 Hs 23128 ESTs 83
429503 AA394183 Hs 26873 ESTs 82
429984 AL050102 Hε 227209 hypothetical protein FLJ21617 8 1
443837 AI984625 Hε 9884 spindle pole body protein 80
449048 Z45051 Hs 22920 similar to S68401 (cattle) glucose indue 80
444880 AW118683 Hs 154150 ESTs 79
417407 AA923278 Hs 290905 ESTs, Weakly similar to protease [H sapi 79
436962 AW377314 Hs 5364 DKFZP564I052 protein 79
450313 AI038989 Hs 332633 Bardet Biedl syndrome 2 76
420120 AL049610 Hs 95243 transcription elongation fxtor A (Sll)- 75
438613 C05569 Hs 243122 hypothehcal protein FLJ13057 similar to 74
419078 M93119 Hs 89584 msulinoma assxiated 1 74
425905 AB032959 Hs 318584 novel C3HC4 type Zinc finger (ring finge 73
451900 AB023199 Hs 27207 KIAA0982 protem 73
447769 AW873704 Hs 320831 Homo sapiens cDNA FU 14597 fis clone NT 73
452436 BE077546 Hs 31447 ESTs, Moderately similar to A46010 X-lm 73
452359 BE167229 Hs 29206 hypothetical protein MGC14376 72
425018 BE245277 Hs 154196 E4F transcription factor 1 72
447737 AK000643 Hs 19404 DKFZP564L0862 protein 72
424897 D63216 Hs 153684 fnzzled-related protein 71
433867 AK000596 Hs 3618 hippxalcm-like 1 7 1
427308 D26067 Hs 174905 KIAA0033 protein 7 1
432359 AA076049 Hs 274415 Homo sapienε cDNA FU10229 fis, clone HE 70
452221 C21322 Hs 288057 hypothetical protein FU22242 70
416051 AA835868 Hs 25253 mannosidaεe, alpha, clasε 1A, member 1 69
421181 NM 005574 Hs 184585 LIM domain only 2 (rhombotin-like 1) 69
448076 AJ133123 Hε 20196 adenylate cyclase 9 69
426759 AI590401 Hs 21213 ESTs 68
416292 AA179233 Hs 42390 nasopharyngeal carcinoma susceptibility 68
417302 BE245812 Hs 8941 ESTs 68
417022 NM 014737 Hs 80905 Ras asεxiation (RalGDS/AF-6) domain fam 67
451957 AI796320 Hs 10299 Homo εapieπs cDNA FU13545 fis, clone PL 67
452859 AI300555 Hs 288158 hypothetical protein FU23591 67
413431 AW246428 Hs 75355 ubiquitin-conjugatmg enzyme E2N (homolo 67
408405 AK001332 Hs 44672 hypothetical protein FU10470 67
421552 AF026692 Hε 105700 secreted frizzled related protein 4 66
426108 AA622037 Hs 166468 programmed cell death 5 66
429490 AI971131 Hε 23889 ESTs, Weakly similarto ALU7.HUMAN ALU S 66
454219 X75042 Hs 44313 v-rel avian reticuloendotheliosiε viral 65
443020 AI350058 Hε 106129 ESTε 65
415752 BE314524 Hs 78776 putative transmembrane protein 64
412482 AI499930 Hs 334885 mitochondnal GTP binding protein 64
417880 BE241595 Hs 82848 selxfin L (lymphxyte adhesion molxule 64
444381 BE387335 Hs 283713 ESTε, Weakly similar to S64054 hypotheti 64
448019 AW947164 Hs 195641 ESTs, Moderately similar to 138022 hypot 63
409799 D11928 Hε 76845 phosphosenne phoεphataεe-like 63
424308 AW975531 Hε 154443 minichromosome maintenance deficient (S 63
411373 BE326276 Hε 8861 ESTs 63
423445 NM 014324 Hs 128749 alpha methylxyl CoA racemase 62
422583 AA410506 Hs 27973 KIAA0874 protein 62
418196 AI745649 Hs 26549 KIAA1708 protein 6 1
438209 AL120659 Hs 6111 aryl hydrocarbon receptor nuclear tranεl 6 1
437147 AL049964 Hs 8358 hypothetical protein FLJ20366 60
432415 T16971 Hs 289014 ESTε, Weakly similar to A43932 mucin 2 p 60
446896 T15767 Hs 22452 Homo sapienε mRNA for KIAA1737 protein 60
408242 AA251594 Hs 43913 PIBF1 gene product 59
447965 AW292577 Hs 94445 ESTε 59 449118 R67477 Hs 23103 Bed (S cerevisiae) homolog 59
427472 AA522539 Hs 131250 transposon-deπved Buster3 tranεpoεase-l 59
431548 AI834273 Hs 9711 novel protem 58
417153 X57010 Hs 81343 collagen, type II, alpha 1 (pπmary oste 58
410889 X91662 Hε 66744 twist (Drosophila) homolog (acrocephalos 58
414734 AA151712 Hε 82572 ESTε 58
429597 NM 003816 Hε 2442 a disintegnn and metalloproteinase doma 58
419047 AW952771 Hs 90043 ESTs 58
435080 AI831760 Hs 155111 hypothetical protein FLJ 14428 58
445715 AB012958 Hs 13137 UV radiation resistance asεxiated gene 58
422538 NM 006441 Hs 118131 5 10 methenyltetrafiydrofolate εynthetaεe 57
431055 AL157645 Hs 48793 εialyltranεferase 6 (N acetyllacosammid 57
434540 NM.016045 Hs 3945 CGI-107 protein 57
452144 AA032197 Hs 102558 Homo sapiens, clone MGC 5352, mRNA, comp 57
407938 AA905097 Hs 85050 phospholamban 57
445467 AI239832 Hs 15617 ESTs, Weakly similar to ALU4_HUMAN ALU S 56
414812 X72755 Hs 77367 monokine induced by gamma interferon 56
448552 AW973653 Hs 20104 hypothetical protein FLJ00052 56
406672 M26041 Hs 198253 major histxompatibility complex, class 55
416111 AA033813 Hs 79018 chromatin assembly fxtor 1 , subunit A ( 55
453942 AW190920 Hs 19928 hypothetical protein SP329 55
416619 AF013168 Hs 79393 tuberous sclerosis 1 55
432485 N90866 Hs 276770 CDW52 antigen (CAMPATH-1 antigen) 55
414516 AI307802 Hs 135560 ESTs, Weakly similar to T43458 hypotheti 55
414343 AL036166 Hs 323378 coated veεicle membrane protein 54
412490 AW803564 Hs 288850 Homo sapiens cDNA FLJ22528 fis, clone H 54
416384 AU076903 Hs 79283 selxtin P ligand 54
453874 AW591783 Hs 36131 collagen, type XIV, alpha 1 (undulm) 54
458079 AI796870 Hs 54277 DNA segment on chromosome X (unique) 992 54
451684 AF216751 Hs 26813 CDA14 54
418758 AW959311 Hs 172012 hypothetical protein DKFZp434J037 54
445757 AW449065 Hs 13264 KIAA0856 protein 54
449907 AA004825 Hs 103281 ESTs 54
419159 AW974945 Hs 268049 hypothetical protein 53
421470 R27496 Hs 1378 annexm A3 53
411486 N85785 Hs 181165 eukaryotic translation elongation fxtor 53
429568 AI088691 Hs 208414 Homo sapieπε mRNA, cDNA DKFZp564D0472 (f 53
403851 C5002154* gι|7299015|gb|AAF54217 1| (AE0 53
428839 AI767756 Hs 82302 Homo εapienε cDNA FLJ14814 fiε, clone NT 53
417426 NM 002291 Hs 82124 laminin, beta 1 53
424624 AB032947 Hs 151301 Ca2-πiependent activator protein for εxr 53
426350 NM.003245 Hs 2022 tranεglutammaεe 3 (E polypeptide, prote 53
436476 AA326108 Hs 33829 bHLH protein DEC2 53
422746 NM 004484 Hs 119651 glypican 3 52
437571 AA760894 Hs 153023 ESTε 52
407902 AL117474 Hs 41181 Homo sapiens mRNA cDNA DKFZp727C191 (fr 52
446985 AL038704 Hε 156827 ESTs, Weakly similar to ALULHUMAN ALU S 52
447072 D61594 Hε 17279 tyroεylprotein εulfotranεferase 1 52
449969 AW295142 Hε 180187 Homo sapiens cDNA FLJ 14337 fis, clone PL 52
453204 R10799 Hε 191990 ESTs 52
452092 BE245374 Hs 27842 hypothetical protein FLJ 11210 51
438510 AL080220 Hs 6285 DKFZP586P0123 protein 51
444917 R68651 Hε 144997 ESTs 51
414212 AA136569 Hs 10848 KIAA0187 gene product 51
451593 AF151879 Hs 26706 CGI-121 protein 51
417318 AW953937 Hs 240845 ESTs 51
444172 BE147740 Hs 104558 ESTs, Moderately similar to I38022 hypot 51
433600 R42833 Hs 22232 ESTs 50
434170 AA626509 Hs 122329 ESTε 50
424090 X99699 Hs 139262 XIAP asεxiated factor-1 50
408331 NM 007240 Hs 44229 dual spxificity phosphataεe 12 50
435706 W31254 Hs 7045 GL004 protein 50
417421 AL138201 Hs 82120 nuclear rxeptor subfamily 4, group A, m 50
432897 AF155099 Hs 279780 NY-REN-18 antigen 50
433560 AI925195 Hs 130891 hypothetical protein MGC4400 50
410762 AF226053 Hs 66170 HSKM-B protein 50
421823 N40850 Hs 28625 ESTs 50
417094 NM 006895 Hs 81182 histamme N methyltransferase 49
425397 J04088 Hs 156346 topoisomerase (DNA) II alpha (170kD) 49
451244 AW008798 Hs 343877 hypothetical protein FU20039 49
453370 A1470523 Hs 139336 ATP-bmding cassette, sub-family C (CFTR 49
424259 AK001776 Hs 143954 hypothetical protein FU10914 49
434094 AA305599 Hs 238205 hypothetical protein PRO2013 49
452323 W44356 Hs 292812 ESTs, Weakly similar to T33468 hypotheti 49
437446 AA788946 Hs 101302 ESTs, Moderately similar to CA1 C RAT COL 49
411352 NM 002890 Hε 758 RAS p21 protem activator (GTPase xtiva 48
443062 N77999 Hε 8963 Homo sapieπε mRNA full length insert cDN 48
425242 D13635 Hε 155287 KIAA0010 gene product 48
445800 AA126419 Hs 32944 inositol polyphosphate-4-phosphatase, ty 48
439024 R96696 Hs 35598 ESTε 48
407235 D20569 Hs 169407 SAC2 (suppressor of xtin mutations 2, y 48
430935 AW072916 zinc finger protein 131 (clone pHZ-10) 47
412953 Z45794 Hs 238809 ESTs 47 413450 Z99716 Hs 75372 N acetylgalactoεamimdase, alpha- 47
421863 AI952677 Hs 108972 Homo sapiens mRNA, cDNA DKFZp434P228 (fr 47
437916 BE566249 Hs 20999 hypothetical protein FLJ23142 47
451952 AL120173 Hs 301663 ESTs 47
416155 AI807264 Hε 205442 ESTs, Weakly similar to T34036 hypotheti 47
451831 NM 001674 Hs 460 activating transcription factor 3 47
414522 AW518944 Hs 76325 εtep II εplicmg factor SLU7 47
427176 AW381569 Hε 40334 ESTε 47
441390 AI692560 Hε 131175 ESTε 47
447382 AW027790 Hs 182261 ESTs 47
431676 AI685464 gb tt88f04 x1 NCI_CGAP_Pr28 Homo sapienε 47
422241 Y00062 Hs 170121 protem tyroεine phosphatase, rxeptor t 47
452242 R50956 Hs 159993 gycosyltranεferase 47
401519 C15000476* gι|12737279|reflXP_0121631| 46
414342 AA742181 Hε 75912 KIAA0257 protein 46
426197 AA004410 Hs 100009 xyl-Coenzyme A oxidase 1, palmitoyl 46
429467 NM.004477 Hs 203772 FSHD region gene 1 46
414341 D80004 Hs 75909 KIAA0182 protein 46
408380 AF123050 Hs 44532 diubiquitm 46
431393 AW971493 Hs 134269 ESTs Highly similar to cytokine recepto 46
425907 AA365752 Hs 155965 ESTs 46
419111 AA234172 Hs 137418 ESTs 46
425840 AW978731 Hs 301824 hypothetical protein PR01331 46
414020 NM 002984 Hs 75703 small inducible cytokine A4 (homologous 45
427078 AI676062 Hs 111902 ESTs 45
419326 W94915 Hs 42419 ESTε 45
419465 AW500239 Hs 21187 Homo εapiens cDNA FLJ23068 fis, clone L 45
408705 AA312135 Hs 46967 HSPC034 protein 45
429250 H56585 Hs 198308 tryptophan πch basic protein 45
431585 BE242803 Hs 262823 hypothetical protein FU 10326 45
449673 AA002064 Hs 18920 ESTs 45
438440 AA807228 Hs 225161 ESTs 45
427210 BE396283 Hs 173987 eukaryotic translation initiation factor 45
428673 AW601325 Hs 337757 Homo sapienε mRNA, cDNA DKFZp566M063 (fr 45
456974 M12529 Hs 169401 apolipoprotein E 44
416814 AW192307 Hs 80042 dolichyl-P-Glc Man9GlcNAc2 PP-dolichylgl 44
443123 AA094538 Hs 272808 putative transcnption regulation πuclea 44
436420 AA443966 Hs 31595 ESTs 44
443250 AI041530 Hs 132107 ESTs 44
411962 AA099050 gb zk85d12 r1 Soares_pregnant_uterus_NbH 44
423545 AP000692 Hs 129781 chromosome 21 open reading frame 5 44
423698 AA329796 Hs 1098 DKFZp434J1813 protein 44
423641 AL137256 Hs 130489 ATPase, ammophospholipid transporter-li 44
430259 BE550182 Hs 127826 RalGEF-like protein 3, mouse homolog 44
453767 AB011792 Hs 35094 extracellular matnx protein 2, female o 44
428328 AA426080 Hs 98489 ESTs, Weakly εimilar to I38022 hypotheti 44
442281 N34742 Hs 170065 Homo εapienε cDNA FU13492 fis, clone PL 44
436446 AW016809 Hs 119021 ESTs 43
450704 H85157 Hs 40696 ESTs 43
438666 AW014493 Hs 126727 ESTs 43
417308 H60720 Hs 81892 KIAA0101 gene product 43
428826 AL048842 Hs 194019 attractin 43
444212 AW503976 Hs 10649 basement membrane-induced gene 43
447188 H65423 Hε 17631 hypothetical protein DKFZp434E2135 43
447858 AW080339 Hε 80426 ESTs 43
418299 AA279530 Hε 83968 integnn, beta 2 (antigen CD18 (p95), ly 43
426827 AW067805 Hε 172665 methyleπetetrahydrofolate dehydrogenase 43
432882 NM 013257 Hs 279696 serum glucxorticoid regulated kmase-li 43
425235 AA353113 Hs 112497 Homo sapienε cDNA FLJ22743 fiε, clone H 43
417986 AA481003 Hs 97128 ESTε 43
438828 AL134275 Hs 6434 hypothetical protein DKFZp761F2014 43
408088 AW157022 Hε 343551 hypothetical protein FLJ22584 43
410853 H04588 Hε 30469 ESTε 43
414002 NM 006732 Hε 75678 FBJ murine oεteoεarcoma viral oncogene h 42
431318 AA502700 Hs 293147 ESTε, Moderately similar to A46010 X-lin 42
408554 AA836381 Hs 315111 nuclear rxeptor co-repressor/HDAC3 comp 42
416782 L35035 Hs 79886 πbose 5-phosphate lεomerase A (πboεe 5 42
418701 AA814948 Hε 96343 ESTs, Weakly similar to ALUC.HUMAN »" 42
419083 AI479560 Hε 98613 Homo sapienε cDNA FLJ12292 fis, clone MA 42
429900 AA460421 Hs 30875 ESTs 42
437672 AW748265 Hs 5741 flavohemoproteiπ b5? 42
439518 W76326 gb zd60d04 r1 Soares.fetal.heart NbHH19W 42
450661 AW952160 Hs 146550 ESTε 42
443907 AU076484 Hs 9963 TYRO protein tyroεine kinase binding pro 42
409151 AA306105 Hs 50785 SEC22, vesicle trafficking protein (S c 42
430968 AW972830 gb EST384925 MAGE resequences MAGL Homo 42
456804 AI421645 Hs 139851 caveolm 2 42
414291 AI289619 Hs 13040 G protein-coupled rxeptor 86 42
420544 AA677577 Hs 98732 Homo sapienε Chromoεome 16 BAC clone CIT 42
448430 AI500642 Hs 289067 Homo εapienε cDNA FLJ 11404 fis, clone HE 42
429570 BE242256 Hs 2441 KIAA0022 gene product 42
444100 AA383343 Hs 22116 CDC14 (cell division cycle 14, S cerevi 42
443622 AI911527 Hs 11805 ESTs 41 436576 AI458213 Hs 77542 ESTs 41
443958 BE241880 Hs 10029 cathepsin C 41
410037 AB020725 Hs 58009 KIAA0918 protein 41
411968 AI207410 Hs 69280 Homo sapiens clone IMAGE 3636299, mRNA 41
421129 BE439899 Hs 89271 ESTs 41
421492 BE176990 Hs 104916 hypothetical protein FLJ21940 41
428966 AF059214 Hs 194687 cholesterol 25 hydroxylase 41
430383 AI861854 Hs 210778 hypothetical protein FLJ 10989 41
431475 AI567669 Hs 40342 putative nuclear protein 41
446468 AI765890 Hs 16341 MAWD binding protein 41
448664 AI879317 Hs 334691 splicing factor 3a, subunit 1, 120kD 41
404390 Target Exon 41
408815 AW957974 Hs 25485 hypothetical protein FLJ22341 41
417512 X76534 Hs 82226 glycoprotein (transmembrane) nmb 41
414888 AL039185 Hs 77558 thyroid hormone rxeptor interactor 7 41
418295 AW970043 Hε 238039 hypothetical protein FLJ11090 41
432242 AW022715 Hε 162160 ESTs, Weakly similar to ALU4 HUMAN ALU S 41
433887 AW204232 Hε 279522 ESTs 41
436556 AI364997 Hs 7572 ESTs 41
430157 BE348706 Hs 278543 ESTs 41
451259 NM.006052 Hs 26146 Down syndrome critical region gene 3 41
458776 AV654978 Hs 19904 cyεtathionase (cystathioniπe gamma lyaεe 41
400301 X03635 Hs 1657 estrogen rxeptor 1 41
443646 AI085198 Hs 164226 ESTε 41
451491 AI972094 Hs 286221 Homo εapiens cDNA FLJ 13741 fis, clone PL 41
452234 AW084176 Hs 223296 ESTs, Weakly similar to I38022 hypotheti 41
430389 AL117429 Hs 240845 DKFZP434D146 protein 40
413275 W94748 Hs 48821 ESTs 40
418432 M14156 Hs 85112 insulin-like growth factor 1 (somatomedi 40
432261 R42216 Hs 12342 Homo sapiens clone 24538 mRNA sequence 40
433409 AI278802 Hs 25661 ESTε 40
452186 AA120761 Hs 28307 WW domain binding protein 4 (formm bind 40
417187 AB011151 Hs 334659 hypothetical protein MGC14139 40
421921 H83363 Hs 6820 traπεlxase of inner mitxhoπdπal membr 40
447247 AW369351 Hs 287955 Homo sapiens cDNA FLJ13090 fis, clone NT 40
415710 J04543 Hs 78637 annexm A7 40
457794 AA689292 Hs 246850 ESTs 40
451124 AI186203 Hs 31432 cardix ankynπ repeat protein 40
424401 H67220 Hs 169681 death effector domain-containing 40
435905 AW997484 Hs 5003 KIAA0456 protein 40
442731 AI868167 Hs 131044 ESTs 40
418650 BE386750 Hs 86978 prolyl endopeptidase 39
423749 U09848 Hs 132390 zinc finger protein 36 (KOX 18) 39
439394 AA149250 Hs 56105 ESTs 39
442287 AW952703 Hs 8182 synaptic nuclei expreεεed gene 1b 39
436758 AW977167 Hs 155272 ESTε 39
451030 H40697 Hs 181426 ESTε, Moderately similar to YSHUT threon 39
405934 Target Exon 39
439231 AW581935 Hs 141480 Homo sapiens mRNA, cDNA DKFZp434N079 (fr 39
444755 AA431791 Hs 113823 ClpX (casemolytic protease X, E coli) 39
447276 AL049795 Hs 17987 hypothetical protein MGC1203 39
431912 AI660552 Hs 76549 ESTs, Weakly similar to A56154 Abl subst 39
428493 AK001745 Hs 184628 hypothetical protein FU 10883 39
412978 AI431708 Hs 820 homeo box C6 39
414962 AF273304 Hs 235376 XPMC2 protein 39
447482 AB033059 Hs 18705 KIAA1233 protein 39
449590 AA694070 Hs 268835 ESTε 39
450203 AF097994 Hs 301528 L-kynuremne/alpha-aminoadipate ammotra 39
450899 T77447 Hs 177864 ESTε 39
423337 NM 004655 Hs 127337 axin 2 (condudm, axil) 38
452588 AA889120 Hs 110637 homeo box A10 38
422661 NM 014700 Hs 119004 KIAA0665 gene product 38
437231 BE303000 Hs 288929 hypothetical protein FU13258 similar to 38
450506 NM 004460 fibroblast xtivation protein, alpha 38
407317 AI204033 Hs 271461 ESTs, Weakly similar to I38022 hypotheti 38
410330 AW023630 Hs 159425 ESTs 38
444143 AW747996 Hs 160999 ESTs, Moderately similar to A56194 throm 38
415156 X84908 Hs 78060 phosphorylase kinase, beta 38
422975 AA347720 Hs 122669 KIAA0264 protein 38
403100 C2001027* gι|7296271|gb|AAF51562 1| (AE0 38
422449 AF168418 Hs 116784 thyroid hormone rxeptor mterxtor 4 38
424163 NM.007071 Hs 142245 HERV-H LTR asεxiatmg 3 38
424806 AA382523 Hs 105689 MSTP031 protein 38
425878 AW964806 Hs 38085 Homo sapiens, Similar to RIKEN cDNA 0610 38
432363 AA534489 gb nf76g11 s1 NCI CGAP_Co3 Homo sapiens 38
443441 AW291196 Hs 92195 ESTs 38
432529 AI989507 Hs 162245 ESTs 38
432908 A1861896 Hs 304505 ESTs 38
424723 BE409813 Hs 152337 protein argmme N methyltransferase 3(h 38
424855 AW204725 Hs 25560 ESTs 38
414664 AA587775 Hs 66295 multi-PDZ-domain-containing protein 38
437162 AW005505 Hs 5464 thyroid hormone rxeptor coactivatmg pr 38
421828 AW891965 Hs 279789 histone deacetylase 3 38 451524 AK001466 Hε 26516 hypothetical protein FLJ10604 3 8
418821 AA436002 Hε 183161 ESTε 38
422049 W25760 Hs 77631 glycine cleavage system protein H (ammo 3 8
453160 AI263307 Hs 239884 H2B histone family, member L 3 8
416072 AL110370 Hs 79000 growth associated protein 43 37
424906 AI566086 Hs 153716 Homo sapienε mRNA for Hmob33 protein, 3' 37
446554 AA151730 Hs 301789 nudix (πucleoεide diphosphate linked moi 37
449523 NM 000579 Hs 54443 chemokine (C-C motif) receptor 5 37
452259 AA317439 Hε 28707 signal sequence rxeptor, gamma (translo 37
417348 AI940507 Hε 318526 hypothetical protein FLJ12661 37
430289 AK001952 Hε 238039 hypothetical protem FLJ11090 37
435401 R44477 Hε 10056 hypothetical protein FLJ14621 37
448807 AI571940 Hs 7549 ESTs 3 7
413403 AA129105 Hs 198425 ESTs, Moderately similar to S65657 alpha 3 7
418323 NM 002118 Hs 1162 major histxompatibility complex, class 3 7
449125 AI671439 Hs 196029 Homo sapienε mRN A for KIAA1657 protein , 37
408089 H59799 Hs 42644 thioredoxm like 37
428242 H55709 Hs 2250 leukemia inhibitory factor (chol ergic 37
439209 AF087993 Hs 91954 ESTε 36
434927 H46612 Hs 293815 Homo sapiens HSPC285 mRNA, partial eds 3 6
431735 AW977724 Hs 75968 thy osin, beta 4, X chromosome 36
456619 AV647917 Hs 107153 inhibitor of growth family, member 1 lik 3 6
458082 AW978811 Hs 314451 ESTs, Weakly similar to ALULHUMAN ALU S 36
411213 AA676939 Hs 69285 neuropilm 1 3 6
414709 AA704703 Hs 77031 Sp2 transcription factor 36
415339 NM 015156 Hs 78398 KIAA0071 protein 36
418203 X54942 Hs 83758 CDC28 protein kmase 2 3 6
427283 AL119796 Hs 174185 ectonucleobde pyrophosphataεe/phosphodi 3 6
452260 AA453208 RAB9, member RAS oncogene family 36
439506 'A1361238 Hs 41136 ESTs 36
420077 AW512260 Hs 87767 ESTs 3 6
451009 AA013140 Hs 115707 ESTs 3 6
436473 AI193122 Hs 132275 ESTs 3 6
413198 AW157712 Hs 47534 ESTs, Weakly similar to I38022 hypotheti 36
443067 AI077389 Hs 269818 ESTs, Weakly similar to Z195JHUMAN ZINC 36
452281 T93500 Hs 28792 Homo sapiens cDNA FLJ 11041 fis, clone PL 36
452561 AI692181 Hs 49169 KIAA1634 protein 36
433269 AI343543 Hs 126890 ESTs 36
445817 NM 003642 Hs 13340 histone acetyltransferase 1 36
447033 AI357412 Hs 157601 ESTε 3 6
414171 AA360328 Hs 865 RAP1A, member of RAS oncogene family 36
427138 N77624 Hs 173717 phoεphatidic xid phoεphatase type 2B 36
442991 BE281238 Hs 8886 hypothetical protein FLJ20424 3 6
434974 AA778711 Hs 4310 eukaryotic translation initiation factor 35
443399 AI452659 Hs 61153 proteasome (prosome, mxropain) 26S subu 35
401807 C7001350 gι|6578126|gb|AAF17706 1|AF0496 3 5
413979 BE218090 Hε 279453 ESTs 3 5
414680 AA743331 hemoglobin, alpha 2 3 5
417380 T06809 Hs 332086 ESTs 35
425710 AFO30880 Hs 159275 solute earner family, member 4 35
441247 AW118681 Hs 128051 Homo sapienε thymic stromal lymphopoiefi 35
445183 AB007877 Hs 12385 KIAA0417 gene product 3 5
426931 NM 003416 Hs 2076 zinc finger protein 7 (KOX 4, clone HF 1 3 5
417873 BE266659 Hs 293659 Homo sapiens, Similar to RIKEN cDNA A430 35
419594 AA013051 Hs 91417 topoisomeraεe (DNA) II binding protein 3 5
446416 AV658299 Hs 163959 ESTε 3 5
449008 AW578003 Hs 22826 tropomodulm 3 (ubiquitous) 3 5
456719 Z43784 ankyπn 3, node of Ranvier (ankyπn G) 35
432101 AI918950 Hs 123642 EphA3 3 5
453565 BE298808 Hs 33363 DKFZP434N093 protein 3 5
449217 AA278536 Hs 23262 πbonuclease, RNase A family, k6 3 5
412922 M60721 Hs 74870 H20 (Drosophιla)-lιke homx box 1 3 5
450066 H56499 Hs 252692 ESTs, Weakly similar to I38022 hypotheti 3 5
429302 AU076674 Hs 198899 eukaryotic translation initiation fxtor 3 5
451246 AW189232 Hs 39140 cutaπ∞us T-cell lymphoma tumor antigen 35
415528 R17236 gb yg12c04 r1 Soares infant brain 1NIB H 35
435513 AW404075 Hs 42785 DC11 protein 35
440643 M78878 Hs 7314 KIAA0614 protein 35
409068 AW236991 Hε 102495 ESTs, Moderately similar to I38022 hypot 3 5
439132 H72803 Hs 38363 ESTs 3 5
451173 AI765082 Hs 48317 ESTs 35
422673 N59027 gb yv59d11 r1 Soares fetal liver spleen 34
401597 AA172106 Rag C protein 34
401744 Target Exon 34
432723 D29677 Hs 3085 KIAA0054 gene product, Helicase 34
449465 NM.004380 Hs 23598 CREB binding protein (Rubinstein Taybi s 34
450628 AW382884 Hs 204715 ESTs 34
432125 AW972667 Homo sapiens cDNA FU 12300 fis, clone MA 34
435411 AW444619 Hs 138211 ESTs 34
434629 AA789081 Hs 4029 glioma amplified εequence 41 34
437158 AW090198 KIAA1150 protein 34
416375 H95567 Hs 124700 ESTs 34
419441 AW023731 Hε 274368 MSTP032 protein 34 432741 AI732358 Hs 185118 ESTε, Moderately similar to A37413 calbi 34
439192 AW970536 Hs 105413 ESTs 34
440474 AI207936 Hs 7195 gamma ammobutyπc acid (GABA) A recepto 34
428466 AF151063 Hε 184456 hypothetical protein 34
447397 BE247676 Hε 18442 E-1 enzyme 34
426828 NM 000020 Hs 172670 activin A rxeptor type ll-like 1 34
418293 AI224483 Hs 16063 hypothetical protein FLJ21877 34
424779 AL046851 Hs 153053 CD37 antigen 34
415015 NM 002109 Hs 77798 histidyl tRNA synthetase 34
425900 AK000166 Hs 288809 hypothetical protein FLJ20159 34
408113 T82427 Hs 194101 Homo sapienε cDNA FLJ20869 fiε, clone A 34
452852 AK001972 Hs 30822 hypothetical protein FLJ11110 34
414671 AA832479 Hs 72080 ESTε 34
431689 AA305688 Hs 267695 UDP-Gal betaGlcNAc beta 1,3-galactosyltr 34
444480 AI150730 Hs 265640 ESTs, Moderately similar to A47582 B-cel 34
403389 C3001393* gι|3327090|dbj|BAA31613 1| (AB 33
440749 W22335 Hε 7392 hypothetical protein MGC3199 33
408374 AW025430 Hs 155591 forkhead box F1 33
410494 M36564 Hε 64016 protein S (alpha) 33
426997 BE620738 Hs 173125 peptidylprolyl lεomerase F (cyclophil 33
433505 AW504027 Hs 15301 Homo sapieπε cDNA FLJ12596 fis, clone NT 33
400277 Eos Control 33
411031 W37943 Hs 34892 KIAA1323 protein 33
417295 AW993524 Hs 43148 ESTs 33
438459 T49300 Hs 35304 Homo sapiens cDNA FU13655 fis, clone PL 33
432169 Y00971 Hs 2910 phosphoπbosyl pyrophoεphate εynthetaεe 33
437872 AK002015 Hs 5887 RNA binding motif protein 7 33
443912 R37257 Hs 184780 ESTε 33
445270 AI762154 Hs 54982 Homo εapieπε cDNA FU14014 fiε, clone HE 33
425836 AW955696 Hs 90960 ESTs 33
414565 AA502972 Hs 183390 hypothetical protein FU 13590 33
418700 AI963808 Hs 86970 ESTs, Moderately similar to ALU5_HUMAN A 33
428186 AW504300 Hs 295605 mannosidase, alpha, claεs 2A, member 2 33
436499 AJ276678 Hs 283102 HEF like Protein 33
448164 R61680 Hε 26904 ESTs, Moderately similar to Z195 HUMAN Z 33
426848 H72531 Hε 36190 ESTs 33
439653 AW021103 Hs 6631 hypothetical protein FLJ20373 33
450094 AI174947 Hs 295789 Homo sapienε mRNA, cDNA DKFZp564D1164 (f 33
402474 NM.004079 Homo εapienε cathepεm S (CTSS 33
424800 AL035588 Hs 153203 MyoD family inhibitor 33
430280 AA361258 Hs 237868 interleukin 7 receptor 33
408968 AI652236 Hs 49376 hypothetical protein FU20644 33
453548 AL079983 Hs 116774 integnn, alpha 1 33
451367 AA923729 Hs 26322 cell cycle related kinaεe 32
444445 AA342329 Hs 115920 Homo εapienε cDNA FLJ22816 fis, clone K 32
445472 AB006631 Hs 12784 Homo sapieπε mRNA for KIAA0293 gene, par 32
400658 ENSP00000237081* KIAA1217 PROTEIN (FRAGM 32
408101 AW968504 Hs 123073 CDC2-related protein kinase 7 32
410366 AI267589 Hs 302689 hypothetical protein 32
411048 AK001742 Hs 67991 hypothetical protein DKFZp434G0522 32
421246 AW582962 Hs 102897 CGI-47 protein 32
422763 AA033699 Hs 83938 ESTs, Moderately similar to MAS2.HUMAN M 32
426227 U67058 Hs 154299 Human proteinase activated rxeptor-2 mR 32
439047 AW979177 gb EST391287 MAGE reεequenceε, MAGP Homo 32
444451 AV650179 Hs 282431 ESTε 32
420568 F09247 Hs 247735 protxadheππ alpha 10 32
406973 M34996 Hs 198253 major histxompatibility complex, clasε 32
402802 NM 001397 Homo εapienε endothelin conver 32
431304 BE157283 gb RC4-HT0373430200-011-a03 HT0373 Homo 32
406247 Target Exon 32
411653 AF070578 Hs 71168 Homo sapiens clone 24674 mRNA sequence 32
412639 AW961284 Hε 296235 ESTε 32
419168 AI336132 Hs 33718 Homo εapieπε cDNA FU12641 fis, clone NT 32
433561 BE540937 Hs 20104 hypothetical protein FU00052 32
436207 AA334774 Hs 12845 hypothetical protein MGC13159 32
438461 AW075485 Hs 286049 phosphoseπne aminotransferase 32
455473 AW984788 gb RC1-HN0015-120400-021-C07 HN0015 Homo 32
441683 BE564214 Hε 102946 ESTs 32
417386 AL037228 Hs 82043 D123 gene product 32
427286 AW732802 Hs 2132 epidermal growth factor rxeptor pathway 32
442355 AA456539 Hs 8262 lysoεomal-aεεxiated membrane protein 2 32
422473 U94780 Hs 117242 menmgioma expressed antigen 6 (coiled-c 32
407816 AW500857 Hs 40137 anaphase-promoting complex 1, meiotic ch 32
458809 AW972512 Hs 20985 sm3-asεxιated polypeptide, 30kD 32
453864 AW021407 Hs 21068 hypothetical protein 32
448944 AB014605 Hs 22599 atrophιn-1 interacting protein 1, xtivi 32
435129 AI381659 Hs 267086 ESTε 32
424894 H83520 Hs 153678 reproduction 8 32
416959 D28459 Hs 80612 ubiquitin-conjugating enzyme E2A (RAD6 h 32
410185 BE294068 Hs 737 immediate early protein 32
451149 AL047586 Hs 10283 RNA binding motif protein 8B 32
410531 AW752953 gb QV0-CT0224-261099-035-g02 CT0224 Homo 32
411954 AA652523 Hs 269496 ESTε, Weakly similar to I38022 hypotheti 32 423748 AI149048 Hs 30211 hypothetical protein FLJ22313 32
444489 AI151010 Hs 157774 ESTs 32
453124 AI139058 Hs 125790 leucine-πch repeat containing 2 32
452413 AW082633 Hs 212715 ESTs 3 1
409390 AI927212 Hs 3734 ESTs 3 1
453078 AF053551 Hs 31584 metaxm 2 3 1
453024 AW846787 gb QV3-CT0194-181099 004 e01 CT0194 Homo 3 1
439444 AI277652 Hs 54578 ESTs, Weakly similar to I38022 hypotheti 3 1
441124 T97717 Hs 119563 ESTs 31
416128 AA173632 CDC14 (cell division cycle 14, S cerevi 3 1
445101 T75202 Hs 12314 Homo sapiens mRNA, cDNA DKFZp586C1019 (f 3 1
407949 W21874 Hs 247057 ESTs Weakly similar to 2109260A B cell 3 1
413492 D87470 Hs 75400 KIAA0280 protein 3 1
421044 AF061871 Hs 101302 Human DNA sequence from clone RP1-238D15 31
422603 BE242587 Hs 118651 hematopoietically expressed homxbox 31
427399 NM 014883 Hs 177664 KIAA0914 gene product 3 1
434804 AA649530 Hs 348148 gb πs44f05 s1 NCI CGAP Alv1 Homo sapienε 3 1
442906 AW296888 Hs 170939 ESTε 3 1
445840 AI277811 Hs 146291 ESTs 31
446084 AL137658 Hs 13768 Homo sapiens mRNA, cDNA DKFZp434l1216 (f 31
435293 AI040777 Hs 117170 ESTs 3 1
400750 Target Exon 3 1
416852 AF283776 Hs 80285 Homo sapienε mRNA, cDNA DKFZp586C1723 (f 3 1
423566 AW976434 Hs 3623 hypothetical protein FLJ11220 31
409558 BE253407 Hs 72363 Homo εapiens mRNA for FLJ00116 protein, 31
400194 NM.003763 Homo εapiens syntaxm 16 (STX1 3 1
400479 Target Exon 3 1
402895 ENSP00000252117 Myelin transcription fx 3 1
403423 Target Exon 31
408161 AW952912 Hs 300383 hypothetical protein MGC3032 31
410886 AW809324 gb MR4-ST0121-141099 010 G06_1 ST0121 Ho 3 1
414922 D00723 Hs 77631 glycine cleavage syεtem protein H (ammo 3 1
420121 AW968271 Hs 191534 ESTε, Weakly similar to ALULHUMAN ALU S 3 1
430519 AF129534 Hs 49210 F-box only protein 4 31
447147 AA910353 Hs 292815 ESTs, Weakly similar to T23482 hypotheti 3 1
422481 AL050163 Hs 117339 DNAX-activation protein 10 3 1
430487 D87742 Hs 241552 KIAA0268 protein 31
409549 AB029015 Hs 54886 phospholipase C, epsilon 2 31
423554 M90516 Hs 1674 glutamine-fructose 6-phosphate transamm 3 1
431286 AW263476 Hs 44268 myelin gene expression factor 2 3 1
430226 BE245562 Hs 2551 adrenergic, beta 2-, rxeptor, surfxe 31
408051 AI623351 Hs 172148 ESTs 31
420090 AA220238 Hs 94986 nbonuclease P (38kD) 3 1
400296 AA305627 Hs 139336 ATP-bindmg casεette, sub-family C (CFTR 3 1
414279 AW021691 GCN5 (general control of ammo-xid synt 3 1
440426 AI159800 Hs 7181 Homo εapienε cDNA FLJ13663 fis, clone PL 31
423872 AB020316 Hs 134015 uronyl 2-sulfotranεferase 3 1
420154 AI093155 Hs 95420 JM27 protein 3 1
447560 AF065214 Hs 18858 phospholipase A2, group IVC (cytosolic, 3 1
453293 AA382267 Hs 10653 ESTs 31
434398 AA121098 Hε 3838 serum-mducible kinase 30
414135 NM.004419 Hs 2128 dual spxificity phoεphataεe 5 30
441527 W19504 Hs 7884 solute earner family 21 (organic amon 30
423957 AW978309 Hs 136235 Homo sapienε cDNA FLJ13542 fis, clone PL 30
444001 AI095087 Hs 152299 ESTs, Moderately similar to S65657 alpha 30
411315 AW836547 gb PM3-LT0032-030100 006-e08 LT0032 Homo 30
414178 AW957372 Hs 46791 ESTs, Weakly similar to I38022 hypotheti 30
441401 AI824338 Hs 126891 ESTs 30
457718 F18572 Hs 22978 ESTs, Weakly similar to ALU4.HUMAN ALU S 30
429500 X78565 Hs 289114 hexabrxhion (tenascm C, cytotxtin) 30
424240 AB023185 Hs 143535 calcium/calmodulm-dependent protein km 30
447476 8E293466 Hs 20880 ESTs, Weakly similarto I38022 hypotheti 30
419440 AB020689 Hs 90419 KIAA0882 protein 30
421786 AI188653 Hs 21351 ESTs 30
433285 AW975944 Hs 237396 ESTs 30
409997 AI906055 Hs 57749 synaptic nuclei expressed gene 2, KIAA10 30
417874 BE616160 Hs 82829 protein tyrosine phosphataεe, non-rxept 30
420956 AA351584 Hs 100543 Homo εapienε clone 24505 mRNA εequence 30
445345 AW003850 Hs 12532 chromosome 1 open reading frame 21 30
450671 AI356967 Hs 43086 ESTs, Weakly similar to A46010 X-lmked 30
427315 AA179949 Hs 175563 Homo sapiens mRNA, cDNA DKFZp564N0763 (f 30
434953 BE049102 Hs 179982 ESTs, Weakly similar to TRHY.HUMAN TRICH 30
436469 AK001455 Hs 5198 Down εyndrome critical region gene 2 30
428130 AW444985 Hε 77603 ESTε 30
414839 X63692 Hε 77462 DNA (cytosιne-5-)-methyltraπsferase 1 30
445784 AI253155 Hε 146065 ESTs 30
446677 AI800311 Hs 156291 ESTs 30
426448 R06054 gb ye89g07 r1 Soares fetal liver εplxn 30
445921 AW015211 Hs 146181 ESTε 30
406673 M34996 Hs 198253 major hiεtocompatibility complex, clasε 30
430387 AW372884 Hs 240770 nuclear cap binding protem subunit 2 2 30
427157 U51166 Hs 173824 thymine DNA glycosylase 30
435907 AW304025 Hs 258397 ESTs 30 451102 AA015683 Hs 41185 Homo sapiens mRNA, cDNA DKFZp56401262 (f 30
416882 AI633044 tryptophanyl tRNA synthetase 2 (mitochon 30
414052 AW578849 Hs 283552 ESTε, Weakly similar to unnamed protein 30
450580 N40087 ESTs 30
TABLE 62B
Pkey Unique Eos probeset identifier number CAT number Gene cluster number
Accesεion Genbank acceεsioπ numberε
Pkey CAT Number Accession
410531 1207200 1 AW752953 H88044 BE156092
410886 1225822 1 AW809324 BE144977 BE144956
411315 1238570 1 AW836547AW836513 AW836587
411962 126744 1 AA099050AA099526T47733
414279 143227.1 AW021691 AI537404 R45431 AI333439 AI741845 AI674468 R44190 R52535 R52617 AI220925 A1979148 AI744688AW242437 AA618148
AI983837 AA399623 A1676204 AI420077 N24944 D51042 AA282786 AA137264 AW236107 AW769
414680 147525J AA743331 AA837388 AW664540 AA775711 AA150965 BE465475 AA968994 AA886905 AI141054 AW194991 AA252147 AA319500 AI184288
AA708749 AA644620 AA652769 AA242975 AA151074 T19890
415528 1539409 1 R17236 R52580 F11642
416128 157163 1 AA173632 AI174858 AA581361 AI700024 AA173988 BE165417 AI366964
416882 162718.1 AI633044 AW016212 AW241143 AA769058 R43272 AW068958 AA210918 AA293774 AI748815 AI763294 AI333114 AI277384 AI088297 AI468477
AI824624 AW189606 AI631751 Z40749 AI984673 AI671316 AA189024 AW235412 BE1784
422673 219674 1 N59027 AA314694 N53937 R08100
426448 267323 1 R06054 AA378789 AW956453
430935 325772 1 AW072916 AI184913 AA489195 AW466994 AW469044 N59350 AI819642 AI280239 AI220572 AA789302 AI473611 AW841126 D60937
430968 326269 1 AW972830 AA527647 AA489820 AA570362
431304 331286 1 BE157283 BE157287 AA502438
431676 336411 1 AI685464AW971336 AA513587AA525142
432125 341776 1 AW972667 AA526539 AI057032 AW167842
432363 345469 1 AA534489 AW970240 AW970323
437158 43392.5 AW090198 AW173544 AW439860 AW007307 AI762577 W86516 AA160485 AA974203 AI589521 AW451857 AW450602 AI702529 AA630766
AI801808 AW611634 A1393606 AW235356 AW000736 AW468599 AI582546 AA962057 AA523012 AW51
437866 44433.2 AA156781 AW293839 U52054 AA024963 AA778446 BE073977 AW444904 AW602574 BE164040 BE164012 BE163972 BE163974 BE163992
AA837481 AW468444 BE185091 AW468002 AA687333 AA811830 AA581806 AI866686 AI572124 AA04
439047 468139 1 AW979177 AA846994 AA829672
439518 47334 ϊ W76326 AF086341 W72300
450506 836.1 NM.004460 U09278 U76833 AW630055 AW471133 C02434 W45237 AW793518 BE070112 AI587479 AI624429 AW190535 A1446661 AI478772
AW022667 AA528235 AA599775 AW613820 AI435793 AW594230 AI051768 AI200109 AI680296
450580 83929.1 N40087 H12925 AA460779 AA096372 BE160847 AW816890 AW816893 AW816577 AW816891 AW816882 AW816868 AW816889 AW816940
AW816892 AW816941 AW816578 AA029183 T83320 H86850 AA010295 BE160823 Z25353 AA150883 AW8
452260 9074.1 AA453208 NM 004251 U44103 AI671547 N57463 AW007521 AI479232 T82809 R67109 AW796099 AI833027 AI765395 AI763029 AI758228
BE326331 AI934576 AI922378 AW276431 AI718466 N36566 AA904753 BE464245 AI338752 Al
453024 944876.28 AW846787 AW903370 AW903378 AW752032 AW839052 AW839051 AW839054 AW839058 AW903374 AW839045 AW903373 AW903352
AW839043 AW839049 AW903372 AW846755 AW846767 AW903368 AW846766 BE146826 AW839056 AW846802 AW
455473 1292917.1 AW984788 AW984816 AW984811 AW984807 AW984819 AW984790 AW984782 AW984784 AW984780 AW984814 AW984795 AW984793
AW984789 AW984823 AW948021 AW984802 AW984800 AW984799 AW984825 AW984792 AW984821 AW984820 AW
456719 222707.1 Z43784 R13382 AW572911 AA449369 H17037 R19603 AI632565 AW004030 BE502530 Z25032 AA805324 AA449241 A1651825 AI264863
AW196918 AA948267 AI953735 AI263703 AA319159 AW964436 AI903440 AW594171 AI867447 AW2
TABLE 62C
Pkey Unique number corresponding to an Eoε probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495 Sfraπd Indicates DNA strand from which exoπε were predicted NLpoεition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400479 8439786 Minus 115386-116348
400658 8118459 Minus 73525-73644
400750 8119067 Plus 198991-199168,199316-199548
401197 9719705 Plus 176341-176452
401519 6649315 Plus 157315-157950
401597 3293210 Plus 65838-66031
401744 2576349 Plus 14595-14751
401807 7331536 Plus 152325-152912
402474 7547175 Minus 53526-53628,55755-55920,57530-57757
402802 3287156 Minus 53242-53432
402895 9967547 Pluε 85537-85671,86379 86469
403100 8954402 Mmuε 13683-13874
403389 9438331 Minus 163415-163634
403423 7105492 Plus 69340-69615
403851 7708872 Plus 22733-23007
404390 8887030 Minus 39624-40072
405141 8980911 Plus 99861-100054
405934 6758795 Plus 159913-160605
406038 8389537 Plus 37764-37877
406247 7417725 Minus 46234-46461 Table 63A lists about 366 genes significantly down regulated in prostate cancer compared to normal prostate Theεe were εelxted from 59680 probeεets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" normal prostate to "average" prostate cancer tisεues was greater than or equal to 2 5 The "average" normal prostate level was set to the 75* percentile of normal prostate tissues The "average" prostate cancer level was set to the 75* percentile amongεt tumor εamples In order to remove gene specific background levels of non specific hybridization the 10* percentile value amongst all the tisεueε was subtracted from both the numerator and Ihe denominator before the ratio was evaluated
TABLE 63A ABOUT 366 GENES SIGNIFICANTLY DOWN REGULATED IN PROSTATE CANCER COMPARED TO NORMAL PROSTATE
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Axession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of normal prostate tissue to prostate tumor tissue
Pkey ExAccn Unigene ID Unigene Title R1
425932 M81650 Hs 1968 semeπogelm I 894
407245 X90568 Hs 172004 titin 354
425545 N98529 Hs 158295 Homo sapiens, clone MGC 12401, mRNA, com 322
426752 X69490 Hs 172004 titin 295
400440 X83957 Hs 83870 nebulin 207
412519 AA196241 Hs 73980 troponin T1, skeletal, slow 139
413778 AA090235 Hs 75535 myoεm, light polypeptide 2, regulatory, 120
420813 X51501 Hs 99949 prolxtiπ induced protein 11 8
415337 Z44881 Hs 9012 ESTε, Weakly similar to S26650 DNA-bmdi 102
407013 U35637 gb Human nebulin mRNA, partial eds 9 1
433331 AI738815 Hε 117323 ESTs 89
432117 AL036195 Hε 2909 protamine 1 83
453863 X02544 Hs 572 orosomucoid 1 82
431847 AI791314 gb ae46g12 y5 Stratageπe lung carcinoma 74
408855 T83061 Hs 319946 Homo sapiens mRNA for KIAA1727 protein, 7 1
448059 AI459021 Hs 170425 ESTs 68
403612 Target Exon 64
405001 U58196 interleukin enhancer binding fxtor 1 62
441490 N46901 Hs 266720 ESTs 62
435805 AW470260 Hs 48496 ESTs 60
401917 AL050149 RAN binding protein 3 59
455649 BE065051 gb RC1-BT0313-110500017-C04 BT0313 Homo 57
450218 R02018 Hs 168640 ankylosis, progresεive (mouse) homolog 56
404606 Target Exon 56
432326 AI280308 Hs 274361 amiloπde sensitive cation channel 2, ne 55
459708 AA776881 Hs 168812 Homo sapiens cDNA FLJ14132 fis, clone MA 55
440808 AK001339 Hε 7432 hypothetical protein FLJ10477 55
458339 AW976853 Hε 172843 ESTs 52
454278 AF217525 Hs 49002 Down syndrome cell adhesion molxule 52
417032 AA192469 Hs 271838 ESTs 52
434352 AF129505 Hs 86492 εmall muscle protein, X-lmked 5 1
439175 AF086021 Hs 271113 ESTs 50
439749 AL389942 Hs 157752 Homo sapiens mRNA full length insert cDN 49
417364 N73749 Hs 222475 ESTs 49
400831 C11000936 gι|3746443|gb|AAC63969 1| (AF0 48
416935 AA190712 gb zp87f09 r1 Stratagene HeLa cell s393 48
442082 R41823 Hs 7413 ESTs 48
452625 AA724771 Hs 61425 ESTs 47
440965 AI523646 Hs 169859 ESTs 47
456815 NM 013348 Hs 144011 potasεium inwardly-rectifying channel.su 47
430611 AA837120 Hs 156481 ESTs 46
415981 R35694 gb yg67b04 r1 Soares infant brain 1NIB H 46
441040 AW449782 Hs 178803 ESTs 46
442764 AI762254 Hs 131122 ESTs 46
411426 BE141714 gb QV0-HT0101-061099 032-CO4 HT0101 Homo 46
433081 Z85986 Hs 188757 Homo sapienε, clone MGC 5564, mRNA, comp 46
401896 Target Exon 45
445323 AW207282 Hs 213049 ESTε 45
458895 AI535663 Hs 39379 ESTs 45
417729 Z43798 Hs 6777 ESTs 45
431627 AW609720 Hs 265540 HSPC042 protein 45
420721 AA927802 Hs 159471 ZAP3 protein 44
449519 W04244 Hs 49829 ESTs 44
442089 AI801500 Hs 128457 ESTs 44
436781 AI914535 Hs 221377 ESTs 44
402797 Target Exon 44
404267 NM 004348* Homo sapienε runt-related fra 43
442931 AI024376 Hs 150473 ESTs 43
418626 AW299508 Hs 135230 ESTs 43
423772 AA306637 EAP30 subunit of ELL complex 43
457136 AA428240 Hs 126083 ESTs 43
436404 AW968556 Hs 137240 Homo sapienε mRNA for partial 3'UTR, εeq 43
458840 AI580296 Hs 174782 ESTε, Weakly εimilar to KIAA1437 protein 43
403649 Target Exon 42
435866 AA704538 Hs 119740 ESTε 42
423871 AA331906 gb EST35805 Embryo, 8 week I Homo εapien 42 436190 AK001059 gb Homo sapiens cDNA FLJ10197 fis, clone 42
400164 Eos Control 41
435519 AI218950 Hs 125461 hypothetical protein FLJ 11539 41
425094 AI955956 Hs 21417 ESTs 4 1
415928 R46799 Hs 23966 ESTs 4 1
415746 AA167670 Hs 21413 εolute earner family 12, (potassium-chl 4 1
426663 AI028767 Hs 262603 ESTε 41
453752 AL120800 gb DKFZp762E152_r1 762 (εyπonym hmel2) 4 1
404260 Target Exon 40
453412 AJ003290 gb AJ003290 Selected chromosome 21 cDNA 40
401411 ENSP00000247172* HYPOTHETICAL 1262 kDa 40
415925 H09474 Hs 202341 Homo sapiens cDNA FLJ23573 fis, clone L 40
402817 H24185 hypothetical protein 40
449233 BE048401 Hs 196511 ESTs 39
435457 AA682421 Hs 59125 ESTs 39
444105 AW189097 Hs 166597 ESTs 39
430610 AI821465 Hs 188810 ESTs, Weakly similar to ALU6 HUMAN ALU S 39
411320 AW836646 gb PM3 LT0032090100 008 e05 LT0032 Homo 38
409679 BE250521 ras homolog gene family, member A 38
415386 Z43087 gb HSC13A121 normalized infant brain cDN 38
446175 AL036568 Hs 291 glutamyl aminopeptidase (aminopeptidase 38
459707 AA631362 Hs 120866 gb np86b01 s1 NCI_CGAP_Thy1 Homo εapieπs 38
406917 X65964 gb H sapiens nestin gene 38
455887 BE154173 gb PM1-HT0340 201299-004412 HT0340 Homo 38
443313 AI796730 Hs 55513 ESTs 38
452351 AA025647 gb ze85d01 r1 Soares fetal heart NbHH19W 38
400499 C10001858 gι|6679124|ref|NP 032759 1| πe 37
411829 AW865749 gb QV3-SN0021-100500-185-C03 SN0021 Homo 37
408229 AW176091 gb QV0-BT0107-250899 007-b08 BT0107 Homo 37
427318 AF186081 Hs 175783 zinc transporter 37
417620 R02530 Hs 191198 ESTs 37
404660 C9000841 * gι|12654691 |gb|AAH01185 1 |AAH0 37
409144 AW341187 Hs 279714 ESTε 37
436524 AA922236 Hs 221037 ESTε 37
459200 Y09306 Hs 30148 homeodomain interacting protein kinaεe 3 37
418833 AW974899 Hs 292776 ESTε 37
424887 AA348112 Hs 259461 ESTs 37
404984 Target Exon 37
454549 AW806910 gb QV4-ST0023-160400-172404 ST0023 Homo 37
426736 AA431615 Hs 130722 ESTs 37
434552 AA639618 Hs 325116 Homo sapienε, clone MGC 2962, mRNA, comp 36
438040 AI222422 Hs 121846 ESTs 36
443618 T82009 Hs 300700 hypothetical protein FU20727 36
442097 AW015799 Hs 128474 ESTs 36
435186 AL119470 Hs 145631 ESTs 36
429853 AB020625 Hs 225949 butyrophiliπ-like 3 36
456521 AW373450 Hs 286212 hypothetical protein FU11729 36
453282 AK000043 Hs 32922 hypothetical protein FU20036 36
400749 NM.003105* Homo sapienε εortilin related 36
450295 AI766732 Hs 210628 ESTε 35
421154 AA284333 Hs 287631 Homo sapiens cDNA FLJ 14269 fis, clone PL 35
434378 AA631739 Hs 335440 EST 35
421342 AA504749 gb aa63f08 r1 NCI.CGAP.GCB1 Homo sapiens 35
406704 M21665 Hs 929 myosin, heavy polypeptide 7, cardix mus 35
429043 AI824977 Hε 145319 ESTs 35
438211 T08401 Hs 290856 ESTs, Moderately similar to ALU4.HUMAN A 35
405258 Target Exon 34
440207 AI371978 Hs 128326 ESTs 34
445045 AI652676 Hs 147256 ESTs 34
406177 Target Exon 34
438535 L09078 gb Homo sapieπε mRNA fragment 34
405735 ENSP00000252164* KIAA1578 protein (Fragm 34
445797 AI253414 gb aq14f04 x1 Stanley Frontal NS p∞l 2 34
444286 AI625304 Hs 190312 ESTε 34
442027 AI652926 Hs 128395 ESTs 34
447889 AW469180 Hs 346398 ESTs 34
405152 Target Exon 34
402460 C1001261* gι|2695979|emb|CAA70854 1| (YO 34
448516 AW898595 gb RC1-NN0073-260400 011-g09 NN0073 Homo 34
450588 AA010319 Hs 60389 ESTs 34
447600 AI420990 ESTε 34
406085 Target Exon 33
417959 AW977642 Hs 291742 ESTs 33
418672 L44284 Hs 12915 ESTs 33
446593 W79572 Hs 13277 hypothetical protein FLJ22054 33
446516 AW996692 Hs 257557 ESTs, Weakly similar to I38022 hypotheti 33
415896 H08311 Hs 14822 ESTs, Weakly similar to I78885 seπne/th 33
410140 AL134435 Hs 247837 neurexin 3 33
458539 AI733837 Hs 145661 ESTs 33
422399 AW410380 Hs 116056 mesenchymal stem cell protein DSC43 33
413381 BE090690 gb RC1-BT0720 280300 011-g02 BT0720 Homo 33
429422 AK001494 Hs 202596 Homo sapiens cDNA FLJ10632 fis, clone NT 33
428561 AW973652 Hs 283105 ESTs 32 445608 AI830851 Hs 200014 ESTs, Weakly similar to ACIDIC PROUNE-R 32
449017 AW002425 Hs 224142 ESTs 32
415908 H08623 Hs 22833 ESTε 32
457733 AW974812 Hs 291971 ESTε 32
449340 AW235786 Hs 195359 hypothetical protein MGC10954 32
428134 AA421773 Hs 161008 ESTε 32
434407 AW815333 gb QV0-ST0215 060100 083 g01 ST0215 Homo 32
429973 AI423317 Hs 164680 ESTε 32
418092 R45154 Hs 338439 ESTε 32
411356 H45377 gb yπ99h03 r1 Soareε adult brain N2b5HB5 31
443366 AI053501 Hs 278869 ESTε, Moderately similar to 2109260A B c 3 1
422069 AJ010063 Hs 343603 titm-cap (telethonm) 3 1
420778 AW970512 gb EST382593 MAGE resequences, MAGK Homo 3 1
403451 Target Exon 3 1
451686 AA059246 Hs 110293 ESTs 3 1
423837 AW937063 Hε 275150 gb PM3 DT0037-231299 001-g11 DT0037 Homo 3 1
422731 AL138411 gb DKFZp434A1229 r1 434 (synonym htes3) 31
450049 AI681234 Hs 258509 EST 3 1
428656 AB037798 Hs 188790 KIAA1377 protein 3 1
401278 Target Exon 31
418087 AA961613 Hs 127838 ESTs 31
421813 BE048255 gb tz49b05 y1 NCI_CGAP_Brn52 Homo sapien 3 1
402490 Target Exon 3 1
448001 AW293237 Hs 202037 ESTs 31
445316 AI219833 Hs 166767 ESTs 31
405150 Target Exon 3 1
413784 BE165819 Hs 207684 ESTs 3 1
425198 AA352090 Hs 128003 hypothetical protein FLJ21213 3 1
433224 AB040919 Hs 210958 KIAA1486 protein 3 1
421894 AI418464 Hs 190836 ESTs 31
419386 AA236867 ESTs, Weakly similar to I38022 hypotheti 3 1
402422 Target Exon 31
435849 BE305242 Hs 16098 claudin 2 3 1
405422 ENSP00000216658* HYPOTHETICAL 1335 kDa 30
420543 AA278221 Hs 173344 ESTs 30
410627 AA181339 Hs 929 myosin, heavy polypeptide 7, cardiac mus 30
409079 W87707 Hs 82065 interleukin 6 signal transducer (gp130, 30
406600 Target Exon 30
408025 AI692784 Hs 41767 PTD002 protein 30
426349 AI308855 Hs 301497 argmyltransferase 1 30
444576 AI400974 Hs 182045 ESTε 30
430661 AC005551 Hs 130714 Homo εapienε HSPC323 mRNA, partial cdε 30
441335 BE222470 Hs 150825 ESTε, Weakly similar to antigen NY-CO-33 30
459647 R34107 Hs 321450 pregnancy spxific beta-1-glycoprotem 1 30
435713 AA699313 Hs 114071 ESTs 30
407275 AI364186 gb qw34h07 x1 NCI CGAP_Ut4 Homo sapiens 30
456103 Z39430 Hs 72350 ESTs 30
435200 AA670310 Hs 145903 ESTε 30
449245 AI636539 Hs 224296 ESTε 30
428132 AA421765 gb zu24g02 s1 Soares NhHMPu S1 Homo sapi 30
443454 AI057494 Hs 133421 ESTε 29
423732 AF058056 Hs 132183 solute earner family 16 (monxarboxylic 29
411944 AW877139 gb QV2-PT0010-160400-133-g01 PT0010 Homo 29
432718 AA563943 Hs 244371 ESTs 29
435534 AA830927 Hs 117306 ESTs 29
430348 AA476915 Hs 189225 ESTs, Weakly similar to I38022 hypotheti 29
410289 AW901618 Hs 61935 Homo sapiens mRNA, cDNA DKFZp761l071 (fr 29
453126 AA032155 Hs 61622 ESTs 29
459421 AA233154 Hs 12532 chromosome 1 open reading frame 21 29
441543 AI733014 Hs 269715 ESTs 29
442252 AI733395 Hs 129124 ESTs 29
419254 AI469453 Hs 222760 ESTs 29
443727 Z25389 Hs 18459 ESTs 29
419896 Z99362 gb HSZ99362 DKFZphamyl Homo sapiens cDNA 29
453898 AW003512 Hs 232770 arxhidonate lipoxygenase 3 29
415098 D59687 gb HUM056E10B Clontech human fetal brain 29
415131 D61119 gb HUM158C11 B Clontxh human fetal brain 29
406398 Target Exon 29
433942 AW272166 Hs 123465 ESTs 29
400461 Target Exon 29
442640 AI205646 Hs 147220 ESTε 29
438814 AA826278 Hs 249596 ESTε 29
438361 AA805666 Hs 146217 Homo εapiens cDNA FLJ23077 fis, clone L 29
422482 AI439905 Hs 344476 gb tι57g08 x1 NCI_CGAP_Lym12 Homo sapien 28
407142 AA412535 gb zl99b10 s1 SoaresJestis.NHT Homo sap 28
454319 AW247736 Hε 101617 ESTs, Weakly similar to T32527 hypotheti 28
442907 AI023763 Hs 79707 ESTs 28
456075 N73442 gb yz31h09 r1 Soares multiple scleroεiε 28
438690 AA815031 Hs 123598 ESTs 28
452570 AW861293 Hs 336940 Homo sapiens cDNA FU20861 fis, clone A 28
408493 BE206854 Hs 46039 phosphoglycerate mutaεe 2 (muεcle) 28
447556 AI885187 Hs 210710 ESTε, Moderately similar to ALU6 HUMAN A 28
451632 BE005934 Hs 310625 EST 28 426481 AW963941 gb EST376014 MAGE resequences, MAGH Homo 28
401656 Target Exon 28
407269 AJ245210 gb Homo sapiens mRNA for immunoglobulin 28
435754 AA700752 Hs 117341 ESTs 28
433565 AA599763 Hs 112520 ESTs 28
451004 AA044967 gb Zf53d09 r1 Soareε retina N2b4HR Homo 28
425223 AA352825 Hs 146065 gb EST60880 Activated T-cells XX Homo sa 28
405770 NM 002362 Homo sapienε melanoma antigen, 28
456227 T84239 Hs 189788 ESTs 28
454445 AW749432 gb RC3-BT0386-301299-011-a09 BT0386 Homo 28
419494 W01060 Hs 34382 ESTs 28
427639 AW444530 Hs 105362 Homo sapiens, clone MGC 18257, mRNA, com 28
428079 AA421020 Hs 208919 ESTs 27
406337 C14000021 gι|7242973|dbj|BAA92547 1| (AB 27
401884 Target Exon 27
406881 D16154 gb Human gene for cytxhrome P-450c11, e 27
428986 AA442884 Hs 201201 ESTs 27
450044 R66444 Hs 51891 ESTs 27
403630 C3001708*gι|4758028|ref|NP 004360 1| co 27
445514 AI241280 Hs 148906 ESTs 27
446362 AW612481 Hs 104105 ESTs 27
432492 AW275110 Hε 271106 ESTε 27
430889 U22491 Hε 248117 G protein-coupled rxeptor 7 27
434316 AW411330 Hε 118796 annexm A6 27
413155 BE067952 gb CM0-BT0365 061299-122-g09 BT0365 Homo 27
433329 AF015041 Hε 199291 numb (Drosophila) homolog-like 27
446523 NM 003063 Hs 334629 sarcolipm 27
449923 BE258051 gb 601111034F1 NIH MGC.16 Homo sapieπε c 27
453826 AL138129 gb DKFZp547F152_r1 547 (εynonym hfbrl) 27
405678 CX001454 gι|8393794|ref|NP_058681 1| myo 27
432789 D26361 Hs 3104 KIAA0042 gene product 27
455791 BE090689 gb RC1-BT0720-280300-011408 BT0720 Homo 27
449109 AW270992 Hε 120949 ESTε, Weakly similar to ALU7.HUMAN ALU S 27
436255 F01143 Hε 284284 zinc finger 1111 27
415984 R19046 Hs 5010 gb yg21f11 r1 Soares infant brain 1 NIB H 27
402844 C1000118* gι|9951913|ref]NP_062832 1| pr 27
456666 AA452512 Hs 76719 U6 snRNA-assxiated Sm-like protein 27
414620 AA150120 Hs 244621 nbosomal protein S14 27
404979 Target Exon 27
412318 AW936911 Hs 326729 hypothetical protein MGC11082 27
424361 AK001551 Hs 145944 Homo sapienε cDNA FLJ10689 fis, clone NT 27
412542 AW961516 Hs 95097 ESTs 27
441975 AW173248 Hs 344285 EST 27
457021 AW968934 Hs 173108 Homo εapiens cDNA FLJ21897 fiε, clone H 27
457861 AW450205 Hs 305890 BCL2-lιke 1 27
439204 AF087987 Hs 42696 EST 27
415642 U19878 Hs 336224 tranεmembrane protein with EGF-like and 27
446847 T51454 Hs 82845 Homo εapienε cDNA FLJ21930 fiε, clone H 27
443359 AI792583 Hs 135354 ESTε 27
447336 AW139383 Hs 245437 ESTε 27
449045 BE072483 Hs 278337 Homo εapiens cDNA FU11537 fis, clone HE 27
422185 AL117530 Hs 112822 DKFZP434B172 protein 27
436030 R02287 Hs 121052 ESTs 27
449589 AW752437 Hs 135258 ESTs, Weakly similar to ALU7 HUMAN ALU S 26
436092 A1345995 Hs 127383 ESTε 26
415054 AI733907 gb zo86h09 y5 Stratagene ovanan cancer 26
412908 AA121913 Hε 293896 pregnancy-assxiated plasma protem-E 26
409583 AW440117 Hε 256879 ESTs 26
410483 BE163567 gb QV3-HT0460-230200-101-b08 HT0460 Homo 26
435383 R61083 weel (S pombe) homolog 26
426629 AI203933 Hε 97142 ESTs 26
415831 H15145 Hε 30509 ESTs 26
412281 AI810054 Hs 14119 ESTs 26
434898 AW500458 Hs 29956 KIAA0460 protein 26
422229 AF134414 Hs 113271 ABO blood group (traπεferase A, alpha 1- 26
447518 T80061 gb yd22f08 s1 Soares fetal liver spleen 26
458546 AI215667 Hε 175044 ESTs 26
438648 AA813125 Hε 146335 ESTs 26
450399 AW511049 Hs 202007 ESTs 26
420833 R47948 Hs 188732 ESTs 26
453903 AW299606 Hs 232777 ESTs 26
443650 AI698330 Hs 151444 ESTs 26
427419 NM 000200 Hs 177888 histatin 3 26
423741 AA330362 gb EST34074 Embryo, 12 week II Homo εapi 26
451577 N69101 Hs 40730 ESTε 26
441358 AW173212 Hs 129041 ESTε 26
402706 Target Exon 26
436054 AI076262 Hs 119813 ESTε 26
402749 Target Exon 26
442472 AW806859 gb MRO-ST0020-081199-004-C03 ST0020 Homo 26
445762 AI734002 Hs 264590 ESTε, Moderately similar to ALU5.HUMAN A 26
441420 AA932872 gb oo57d07 s1 NCI_CGAP_Lu5 Homo sapiens 26
405564 Target Exon 26 406003 Target Exon 26
459584 AI910884 Hs 346429 ESTs 26
441597 AW135032 Hs 203625 ESTs 26
411280 N50617 Hε 80506 small nuclear ribonucleoprotem polypept 26
420509 M83554 Hs 1314 tumor nxrosis factor rxeptor superfami 26
445060 AA830811 Hs 282908 ESTs 26
436260 BE172762 Hs 292710 ESTε, Weakly similar to ALU5.HUMAN ALU S 26
428717 T78001 Hs 133546 hypothetical protein FLJ21120 26
401716 C16000902 gιl403440Igb|AAA73168 1| (M817 26
416628 W03955 gb za62d04 r1 Soares fetal liver spleen 26
443864 N37059 Hε 36250 ESTs, Weakly similar to I38022 hypotheti 26
440702 AA904178 Hs 148233 ESTs 26
456310 AA225522 gb πc25c06 r1 NCI CGAP.Prl Homo sapiens 26
451255 AA020857 Hs 90744 ESTs 26
455737 BE072246 gb QV4-BT0536-271299-059-b12 BT0536 Homo 26
445326 AI220072 Hε 344672 ESTs 26
408432 AW195262 gb xn67b05 x1 NCI CGAP_CML1 Homo sapiens 26
445874 BE326671 Hs 170058 ESTs 26
441063 AA913819 Hs 188025 ESTs 26
455505 AW970640 Hs 309071 ESTs 26
453491 AL040177 gb DKFZp434F0213 r1 434 (synonym htes3) 26
455048 AW852749 gb PM1-CT0247-080100 008-h09 CT0247 Homo 26
456990 NM 004504 Hs 171545 HIV-1 Rev binding protein 26
444130 AI125263 Hs 170410 ESTs 25
422210 BE269319 Hs 171937 steroid dehydrogenase-like 25
424241 AW995948 Hs 182339 Homo εapiens pyruvate dehydrogenase kma 25
451606 AA018791 Hs 7945 AIE-75 binding protein protein 25
400427 AB044934 Hs 287388 histamme H4 receptor 25
410443 BE062906 Hs 28338 KIAA1546 protein 25
455210 AW866599 gb QV4-SN0024-210400-181-b10 SN0024 Homo 25
429909 AW977090 Hε 184860 CGI-203 protein 25
441191 AI693930 Hε 148816 ESTs 25
413489 BE144228 gb MR0 HT0165-140200-009-d04 HT0165 Homo 25
448215 N34740 Hε 6658 ESTs 25
419354 M62839 Hs 1252 apolipoprotein H (beta-2-glycoproteιn I) 25
447610 AW296286 Hs 255534 ESTs 25
450724 R55428 gb yj79b05 r1 Soares breast 2NbHBst Homo 25
414523 AU076633 Hs 76353 seπne (or cysteine) proteinaεe inhibito 25
414776 AA155598 Hs 212839 hypothetical protein FU14195, KIAA1714 25
447730 AI421251 Hs 114085 Homo εapiens mRNA for K1AA1755 protein, 25
434152 AI792665 Hs 291190 ESTs 25
412671 AW977734 Hε 37931 gb EST389963 MAGE resequenceε, MAGO Homo 25
456401 W28146 gb 43f11 Human retina cDNA randomly prim 25
404678 Target Exon 25
408520 AA225063 Hs 161614 ESTε 25
411332 AW837212 gb QV2-LT0038-140300-081-C01 LT0038 Homo 25
448920 AW408009 Hs 22580 alkylglycerone phoεphate εynthase 25
429906 AL080137 Hs 193743 ESTs 25
433712 AF090887 Hs 306562 Homo sapiens clone HQ0085 25
438353 BE539951 Hs 306996 Homo sapienε, clone IMAGE 3447073, mRNA, 25
446224 AW450551 Hs 13308 ESTs 25
TABLE 63B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank xceεεion numbers
Pkey .CAT Number Accession
408229 1048462 1 AW176091 H24234
408432 1058667 1 AW195262 R27868 AW811262
409679 114787 T BE250521 AA076837 BE249870 AA984291 AW502442 AW501551 AI221491 AA194239 D63046 AA193426 AA773243AA193293
410483 1204995 1 BE163567 BE073689 BE073747 BE073780 BE073739 BE073748 BE163495 AW750178 BE163491 BE073763 BE073671
411320 1238624 1 AW836646 AW836580 AW836610 AW836636 AW836603 AW836632
411332 1239102 1 AW837212 AW837408 AW837265 AW837380 AW837213 AW837411 AW837418
411356 1240273 1 H45377 H21137 AW838640
411426 1245515 1 BE141714 AW845993 AW845989
411829 1260309 1 AW865749 BE179419 BE179492
411944 1266482J AW877139 AW877135 AW877018 AW991835 AW877128 AW877108 AW877017 AW877107
413155 1351148 1 BE067952 BE067945 BE067942 BE067943 BE067949 BE067954 BE067944 BE067953 BE067956 BE067946
413381 1365950 1 BE090690 BE090688 BE090681 BE090693 BE090675
413489 1373392J BE144228 BE144291
415054 151827 1 AI733907 AA159708 A1732614
415098 1522174 1 D59687 D59694 D59656 D59589
415131 1523680 1 D61119 D81508 D81734
415386 1535560 1 Z43087 F07410 H15506 H54108 R95033 H98000
415981 1564242.1 R35694 H12035 R53312
416628 1604848 1 W03955 H82332 H69247 H72486
416935 163179 1 AA190712 AA190665 AA252564
419386 184356 1 AA236867 AA237066 AA354236 AW957759 H08961
419896 1888662.1 Z99362Z99363
420778 196389 1 AW970512 AA280251 AI652287 BE466438 AI650725 AA551854 AA281574 AW571481 421342 201427.1 AA504749 AA287498 421813 207654.1 BE048255 AA313083 AA298419 422731 220507 1 AL138411 AL138412 AA315860 423741 231582 1 AA330362 AW962525 H87796 423772 23188 1 AA306637 NM.007241 AF156102 BE388339 BE614027 AW935016 AA315261 AW376418 AW304951 AI859820 AA367436 AW516957 BE614519
AI453152 AI453149 AI453139 AW168378 AI139491 AI538368 AW468227 AI680027 AW090513 AA662830 F30995 AI351985 AI424349 AW009599
C02215 AI6525
423871 232749.1 AA331906 AA332484
426481 267878.1 AW963941 AW963944 AA379825 AA379564
428132 287430 1 AA421765 AA456076 AI290275 AA455579
431847 338402.1 AI791314 AΪ791434 AA516511
434407 385744.1 AW815333 AW815409 AA632563
435383 405360.1 R61083 R13743 AA679174 AA679193 Z42903
436190 41555.1 AK001059 AA633055
438535 45946.1 L09078 L03145 L09094 L09098 L03165 L09102
441420 516748 1 AA932872 W28068 W28643 T96110
442472 543371.1 AW806859 AW806852 AF049582
445797 650943.1 AI253414 A1366014 R34822
447518 724787 1 T80061 AI382804
447600 728288.1 A1420990 AI399725 A1401757
448516 766241.1 AW898595 AW898588 AW898590 AW898663 AW898592 AI525093
449923 81926.1 BE258051 R45758 AA004732 BE255126
450724 844585 1 R55428 AI820704 AI732283 R54983
451004 85453.1 AA044967 H86327 AA013079 AA058776 BE242713 AA019987
452351 91233.1 AA025647 R45716 AW753786
453412 966264.1 AJ003290 AJ003288 AW276947
453491 969172.-1 AL040177
453752 979899 1 AL120800 BE378580
453826 982669.1 AL138129 AL138179 BE064231
454445 1204468.1 AW749432 AW749434 R47332
454549 1223789.1 AW806910 AW866461 AW866396 AW866373 AW866611 AW866616
455048 1250599.1 AW852749 AW852755 AW852620
455210 1260650.1 AW866599 AW866294 AW866468 AW866467
455649 1348708 1 BE065051 BE155165 BE064764 BE155231 BE064648 BE064671 BE064636
455737 1353892.1 BE072246 BE072229 BE072225 BE072210 BE072221 BE072256 BE072211 BE072242
455791 1365954.1 BE090689 BE090685 BE090697 BE090680 BE090691 BE090696 BE090698 BE090686
455887 1380836.1 BE154173 BE154098 BE154096
456075 1476756 1 N73442 R98100 BE410380
456310 177089.Ϊ AA225522 AA225465 AI820979 AW973985 AI791935 AA558735
456401 1844649 2 W28146 28187
TABLE 63C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " referε to the publication entitled The DNA εequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide xεitionε of predicted exonε
Pkey Ref Strand NLposition
400461 9929654 Pluε 32727-32846,32929-33051
400499 9796071 Minuε 148495-148806
400749 7331445 Minuε 9162-9293
400831 8576271 Minus 56502-57407
401278 9799936 Plus 98428-98573
401411 7799787 Minus 144144-144329
401656 9100664 Minus 1-382
401716 6715703 Plus 174722-174911
401884 8140731 Minus 89182-90053
401896 8569194 Plus 115129-115294
401917 9502466 Plus 25054-25229
402422 9796344 Minus 32843-33008
402460 9796884 Minus 108901-109254,110246-110581,113613-113960
402490 9797648 Pluε 149982-150929
402706 8894426 Mmuε 148640-148805
402749 9212740 Minus 68787-68882,76602-76768
402797 3421043 Minus 15758-15930
402817 6822166 Minus 48611-49012
402844 9369286 Plus 5495855313
403451 9838240 Plus 77382-78300
403612 8469060 Minus 94723-94859
403630 8569999 Minus 13909-14466,15251-15760,16898-17431,4174242440
403649 8705159 Minus 27141-27247
404260 9366879 Plus 51396-51513
404267 9581792 Minus 12209-12313,18241-18397
404606 9212936 Minus 2231023269
404660 9797068 Plus 168215-168916
404678 9797204 Pluε 115196-115448
404979 4160139 Minus 87762-88217
404984 6939882 Plus 87221-87505
405001 6015406 Minus 104646-104819
405150 9929758 Plus 126475-126773 405152 9965561 Minus 137662 137969
405258 7329310 Plus 129930-130076
405422 7243869 Minus 101938 102079 102261-102443,102896-103202
405564 2114222 Minuε 16766-17344
405678 4079670 Pluε 151821-152027
405735 9931101 Mmuε 29854-29976
405770 2735037 Pluε 61057-62075
406003 8247800 Pluε 42079 42516
406085 9123888 Pluε 18665-18843
406177 7279760 Minus 18930-19148
406337 9213455 Plus 90117-90337
406398 9256276 Minus 118691-118959
406600 8248616 Minus 36296 36610
Table 64A lists about 703 genes up regulated in BPH compared to normal adult tisεueε These were selected from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" BPH to "average" normal adult tisεueε was greater than or equal to 30 The "average" BPH level was set to the 75* percentile amongst BPH tissues The "average" normal adult tissue level was set to the 85* percentile amongεt non malignant tissues In order to remove gene-spxific background levels of non-specific hybridization the 10* percentile value amongst the non malignant tissueε was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 64A ABOUT 703 GENES UP-REGULATED IN BENIGN PROSTATIC HYPERPLASIA COMPARED TO NORMAL ADULT TISSUES
Pkey Unique Eos probeset identifier number ExAccn Exemplar Accession number, Genbank accesεion number UnigenelD Unigene number Unigene Title Unigene gene title R1 Ratio of BPH tissue to normal adult body tissue
Pkey ExAccn Unigene ID Unigene Title Rl
420154 AI093155 Hs 95420 JM27 protein 49 6
426747 AA535210 Hs 171995 kallikrein 3, (prostate specific antigen 472
419526 AI821895 Hs 193481 ESTs 43 6
432441 AW292425 Hs 163484 ESTs 427
431616 AA508552 Hs 195839 ESTs, Weakly similar to I38022 hypotheti 30 2
407202 N58172 Hs 109370 ESTs 26 1
432101 AI918950 Hs 123642 EphA3 258
400299 X07730 Hs 171995 kallikrein 3, (prostate specific antigen 25 5
425075 AA506324 Hs 1852 xid phosphatase, prostate 24 6
414569 AF109298 Hs 118258 proεtate cancer aεsxiated protein 1 244
410929 H47233 Hs 30643 ESTs 21 1
400287 S39329 Hs 181350 kallikrein 2, prostatio 203
446057 AI420227 Hs 149358 ESTs, Weakly similar to A46010 X-lmked 198
423073 BE252922 Hs 123119 MAD (mothers against decapentaplegic, Dr 18 6
415989 AI267700 ESTε 17 8
428336 AA503115 Hs 183752 microεeminoprotein, beta- 173
450693 AW450461 Hs 203965 ESTε 167
400298 AA032279 Hs 61635 εix transmembrane epithelial antigen of 167
407168 R45175 Hs 117183 ESTs 15 5
408369 R38438 Hs 182575 solute earner family 15 (H??? transport 155
454119 BE549773 Hs 40510 uncoupling protein 4 145
428819 AL135623 Hs 193914 KIAA0575 gene product 145
400302 N48056 Hs 1915 folate hydrolase (prostate-spxific memb 144
400297 AI127076 Hs 306201 hypothetical protein DKFZp56401278 143
418432 M14156 Hs 85112 msulm-like growth fxtor 1 (somatomedi 142
432674 AA641092 Hs 257339 ESTs, Weakly similar to 138022 hypotheti 142
433444 AW975324 Hs 129816 ESTs 138
432240 AI694767 Hs 129179 Homo sapiens cDNA FLJ13581 fis, clone PL 13 5
428342 AI739168 Homo sapienε cDNA FU 13458 fiε, clone PL 129
401424 NM 001172 Homo εapiens argiπase, type II 127
432435 BE218886 Hε 282070 ESTs 125
448999 AF179274 Hs 22791 transmembrane protein with EGF-like and 123
446100 AW967109 Hs 13804 hypothetical protein dJ4620232 120
425154 NMJ01851 Hs 154850 collagen, type IX, alpha 1 11 9
407275 AI364186 gb qw34h07 x1 NCI_CGAP_Ut4 Homo sapienε 11 8
452340 NM 002202 Hε 505 ISL1 transcription fxtor, LIM/homxdoma 11 7
432473 AI202703 Hs 152414 ESTs 11 3
410330 AW023630 Hs 159425 ESTs 11 2
431579 AW971082 Hs 222886 ESTs, Weakly similar to TRHY HUMAN TRICH 11 2
452792 AB037765 Hs 30652 KIAA1344 protein 11 2
418848 AI820961 Hs 193465 ESTs 109
400292 AA250737 Hs 72472 BMP-R1B 109
433647 AA603367 Hs 222294 ESTs 108
453160 AI263307 Hs 239884 H2B histone family, member L 108
409262 AK000631 Hs 52256 hypothetical protein FLJ20624 106
431474 AL133990 Hs 190642 CEGP1 protein 103
429220 AW207206 ESTs 103
428134 AA421773 Hs 161008 ESTs 102
408622 AA056060 Hs 202577 Homo sapienε cDNA FLJ12166 fiε, clone MA 101
456497 AW967956 Hs 123648 ESTε, Weakly similar to AF108460 1 ubinu 98
434792 AA649253 Hs 132458 ESTs 97
433466 AA508353 Hs 105314 relaxm 1 (H1) 95
439176 AI446444 Hs 190394 ESTs, Weakly similar to B28096 lιne-1 pr 95
428398 AI249368 Hs 98558 ESTs 94 429290 AF203032 Hs 198760 neurofilament heavy polypeptide (200kD) 93
407709 AA456135 Hs 23023 ESTs 93
415293 R49462 Hs 106541 ESTs 9 1
429918 AW873986 Hs 119383 ESTs 91
440260 AI972867 Hs 7130 copine IV 9 1
453096 AW294631 Hs 11325 ESTs 9 1
410467 AF102546 Hs 63931 dachshund (Drosophila) homolog 89
456516 BE172704 Hε 222746 KIAA1610 protein 88
430722 AW968543 Hε 203270 ESTs, Weakly similar to ALULHUMAN ALU S 88
458072 AI890347 Hε 271923 Homo sapiens cDNA FLJ22785 fis, clone K 88
453006 AI362575 Hε 303171 ESTs 87
418339 AA639902 Hs 104215 ESTs, Moderately similar to SPCN_HUMAN S 87
420424 AB033036 Hs 97594 KIAA1210 protein 87
450642 R39773 Hs 7130 copine IV 87
434036 AI659131 Hs 197733 hypothetical protein MGC2849 87
428927 AA441837 Hs 90250 ESTs 86
418829 AA516531 Hs 55999 NK homeobox (Drosophila), family 3, A 85
420345 AW295230 Hs 25231 ESTs 85
446336 AW815036 Hs 151251 ESTs 84
419743 AW408762 Hs 5957 Homo sapiens clone 24416 mRNA sequence 84
428728 NM 016625 Hs 191381 hypothetical protein 83
417169 R13550 Hs 246773 ESTs 82
453387 AI990741 Hs 252809 ESTs 82
434666 AF151103 Hs 112259 T cell rxeptor gamma Ixus 8 1
417958 AA767382 Hs 193417 ESTs 80
433433 AI692623 Hs 121513 Homo sapiens clone Z'3-1 placenta expres 79
444609 AW571659 Hs 278081 ESTs 78
424099 AF071202 Hs 139336 ATP-bindmg cassette, sub-family C (CFTR 78
433923 AI823453 Hs 146625 ESTs 77
437587 AI591222 Hs 72325 Human DNA sequence from clone RP1-187J11 77
441690 R81733 Hs 33106 ESTs 76
453370 AI470523 Hs 139336 ATP-bindmg cassette, sub-family C (CFTR 76
441247 AW118681 Hs 128051 Homo sapienε thymic εtromal lymphopoiefi 75
439444 AI277652 Hs 54578 ESTε, Weakly similar to I38022 hypotheti 75
431448 AL137517 Hs 306201 hypothetical protein DKFZp56401278 74
413597 AW302885 Hs 117183 ESTs 74
404592 NM 022739* Homo sapienε E3 ubiquitin lig 73
409557 BE182896 Hs 211193 ESTs 73
420352 BE258835 gb 601117374F1 NIH MGC 16 Homo sapiens c 73
438231 AW594539 Hs 155689 ESTs 73
440529 AW207640 Hs 16478 Homo sapiens cDNA FU21718 fis, clone C 71
449300 AI656959 Hs 346514 ESTs 71
417332 AW972717 Hs 288462 hypothetical protein FLJ21511 7 1
453930 AA419466 Hs 36727 hypothetical protein FU 10903 7 1
449249 T52285 Hs 193115 Homo sapiens mRNA for KIAA1764 protein, 70
430187 AI799909 Hs 158989 ESTs 70
434217 AW014795 Hs 23349 ESTs 70
431217 NM_013427 Hs 250830 Rho GTPase xtivatmg protein 6 69
430188 AL049242 Hs 234794 Homo sapiens mRNA, cDNA DKFZp564B083 (fr 69
415786 AW419196 Hs 257924 hypothetical protein FLJ 13782 69
421059 AI654133 Hs 30212 thyroid rxeptor interxting protein 15 68
426384 AI472078 Hs 303662 ESTs 68
458509 AA654650 Hs 282906 ESTs 68
449821 AI671141 Hs 211122 ESTs 68
407118 AA156790 Hs 262036 ESTs, Weakly similar to Z223 HUMAN ZINC 68
443250 AI041530 Hs 132107 ESTs 67
428330 L22524 Hs 2256 matnx metalloproteinase 7 (matnlys , 67
408197 AA282262 Hs 107410 ESTs, Weakly similar to A46010 X-lmked 66
454457 AW753456 gb QV2-CT0261-261099 011-d11 CT0261 Homo 66
421154 AA284333 Hs 287631 Homo sapiens cDNA FU14269 fis, clone PL 65
429433 AA452899 Hs 213586 ESTs, Weakly similar to KIAA1353 protein 65
431467 N71831 Hs 256398 Homo sapiens mRNA, cDNA DKFZp434E0528 (f 65
424433 H04607 Hs 9218 ESTs 65
450164 AI239923 Hs 63931 ESTs 65
423566 AW976434 Hs 3623 hypothetical protein FU11220 65
450497 H64159 Hs 15328 ESTε 65
425312 AA354940 Hs 145958 ESTε 64
426140 AF131798 Hs 343768 Homo εapienε clone 25119 mRNA εequence 64
440911 AA909536 Hs 143562 ESTε 64
412350 AI659306 Hs 73826 protein tyroεine phoεphatase, non-recept 63
432600 AI821085 gb ns95a12 y5 NCI CGAP_Pr3 Homo εapienε 63
435375 AI733610 Hs 187832 ESTε 63
416370 N90470 Hε 203697 ESTε, Weakly similar to I38022 hypotheti 63
431359 AW993522 Hs 292934 ESTs 62
424736 AF230877 Hs 152701 microtubule-interacting protein that asε 61
403667 Target Exon 61
424846 AU077324 Hε 1832 neuropeptide Y 6 1
439569 AW602166 Hε 222399 CEGP1 protein 6 1
436396 AI683487 Hε 152213 wmgleεs type MMTV integration site fami 6 1
448004 AW451477 Hs 257456 ESTs 6 1
431770 BE221880 Hs 268555 5' 3' exoπbonudease 2 60
453861 AI026838 Hε 30120 ESTs Weakly similar to NUCL.HUMAN NUCLE 60
415621 AI648602 Hε 55468 ESTs 60 436873 N23874 Hs 50477 RAB27A, member RAS oncogene family 60
442481 N99828 gb za32c04 r1 Soareε fetal liver εpleeπ 60
432527 AW975028 Hs 102754 ESTs 59
447156 AW274731 Hs 157920 ESTs 59
404003 Target Exon 59
424853 BE549737 Hs 132967 Human EST clone 122887 manner tranεpoεo 59
427726 AI359144 Hs 143688 Homo εapienε cDNA FLJ23031 fis, clone L 59
433043 W57554 Hs 125019 lymphoid nuclear protem (LAF-4) mRNA 59
438138 R98299 Hs 177502 ESTs 59
440129 AA865818 Hs 174936 ESTs, Weakly similar to S71886 Ste20 lik 58
434973 AW449285 Hs 313636 EST 58
408527 AL135018 Hs 33074 Homo sapiens, clone IMAGE 3606519, mRNA, 58
459241 AA032276 Hs 99010 ESTs, Moderately similar to T14342 NSD1 58
434485 AI623511 Hs 118567 ESTs 58
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 57
443960 AI093577 Hs 255416 hypothetical protein FLJ21986 57
453200 AA033832 Hs 212433 ESTs 57
428002 AA418703 gb zv98c03 s1 Soareε NhHMPu SI Homo εapi 57
432966 AA650114 Hs 325198 ESTs 57
448148 NM.016578 Hs 20509 HBV pX assxiated protein 8 57
420948 AB016898 Hs 100469 myetoid/lymphoid or mixed lineage leukem 57
425810 AI923627 Hs 31903 ESTs 56
414312 AA155694 Hs 191060 ESTs 56
404571 NM.015902* Homo sapienε progestm induce 56
424850 AA151057 Hs 153498 chromosome 18 open reading frame 1 56
439092 AA830149 gb x44f08 s1 NCLCGAP.GCB1 Homo sapiens 56
427078 AI676062 Hs 111902 ESTs 56
422805 AA436989 Hs 121017 H2A histone family, member A 56
417511 AL049176 Hs 82223 chordiπ like 56
449625 NM 014253 odz (odd Oz/ten m, Drosophila) homolog 1 56
433927 AI557019 Hs 116467 small nuclear protein PRAC 55
441676 BE564206 Hs 49889 ESTε 55
421513 X00949 Hs 105314 relaxm 1 (H1) 55
432682 AI376400 Hs 159588 ESTs 55
435021 AA922192 Hs 54709 ESTs 55
454171 AW854832 gb QV2-CT0261-201099-011405 CT0261 Homo 55
426581 AB040956 Hs 135890 KIAA1523 protein 55
439079 AF085937 Hs 38348 ESTs 55
443635 AI080230 Hs 134214 ESTs 55
400080 Eos Control 55
410196 AI936442 Hs 59838 hypothetical protein FLJ10808 55
436578 AI091435 Hs 134859 ESTs 55
424051 AL110203 Hs 138411 Homo sapiens mRNA, cDNA DKFZp586J1922 (f 54
450325 AI935962 Hs 26289 ESTs 54
421863 AI952677 Hs 108972 Homo sapiens mRNA, cDNA DKFZp434P228 (fr 54
432161 AK000400 Hs 341181 ESTs, Weakly similar to envelope [H sapi 54
435072 AW592176 Hs 116932 ESTs 54
428647 AA830050 Hs 124344 ESTs 54
441111 AI806867 Hs 126594 ESTε 54
433087 AI720686 Hs 152520 ESTs 53
450244 AA007534 Hs 125062 ESTs 53
400294 N95796 Hs 278695 Homo εapienε prostem mRNA, complete eds 53
415539 AI733881 Hs 72472 BMP-R1B 53
437267 AW511443 Hs 258110 ESTs 53
441916 AA993571 Hs 129075 ESTε 53
452784 BE463857 Hs 151258 hypothetical protem FLJ 21062 53
446715 AI337735 Hs 173919 ESTs, Moderately similar to ZN9LHUMAN Z 53
452531 AA429462 Hs 293946 ESTs, Weakly similar to I38022 hypotheti 53
426503 AA380153 gb EST93093 Skin tumor I Homo sapiens cD 53
423101 M83941 Hs 123642 EphA3 53
445704 AI493742 Hs 167700 ESTs, Moderately similar to I38022 hypot 53
450813 AI739625 Hs 203376 ESTs 53
409079 W87707 Hs 82065 interleukin 6 εignal tranεducer (gp130, 52
415890 H08225 Hs 268712 ESTε 52
454968 AW849046 gb IL3-CT021 -150300-085-H06 CT0214 Homo 52
441054 AA913591 Hε 126480 ESTε 52
408385 AF055634 Hs 44553 unc5 (C eleganε homolog) c 52
437752 AA767376 Hs 291631 ESTε, Moderately similar to S65657 alpha 52
448072 AI459306 Hs 24908 ESTs 52
419536 AA603305 gb np12d11 s1 NCI CGAP Pr3 Homo εapienε 52
421040 AA715026 Hs 135280 ESTε 52
446495 D60923 Hs 153460 ESTs 52
415263 AA948033 Hs 130853 ESTs 52
426748 AL048409 Hs 97177 ESTs, Weakly similar to ALULHUMAN ALU S 52
436338 W92147 Hs 118394 ESTs 52
445238 AA883971 Hs 187506 ESTs 5 1
450382 AA397658 Hs 60257 Homo sapienε cDNA FLJ13598 fis, clone PL 51
457211 AW972565 Hs 32399 ESTs, Weakly similar to S51797 vasodilat 51
450582 AI339732 G-πeh RNA sequence binding fxtor 1 5 1
438447 AI082883 Hε 30732 hypothetical protein FLJ13409, KIAA1711 5 1
430598 AK001764 Hε 247112 hypothetical protein FLJ10902 50
440995 T57773 Hε 10263 ESTs 50
412775 AA709046 Hs 27552 Homo sapiens mRNA, cDNA DKFZp586N2424 (f 50 425259 AL049280 Hs 155397 Homo sapiens mRNA cDNA DKFZp564K143 (fr 50
418334 AA319233 Hs 5521 ESTs 50
435401 R44477 Hs 10056 hypothetical protein FLJ14621 50
418564 AA631143 Hs 278695 Homo sapiens prostem mRNA, complete eds 50
407198 H91679 gb yv04a07 s1 Soares fetal liver εpleeπ 50
403696 C4001100* gι|5852342|gb|AAD54015 1| (AF0 50
452891 N75582 Hs 212875 ESTs, Weakly similar to DYH9_HUMAN CILIA 50
457374 AA493662 gb nh05d12 s1 NCI_CGAP_Thy1 Homo sapieπε 50
430261 AA305127 Hε 237225 hypothetical protein HT023 50
408829 NM 006042 Hs 48384 heparan sulfate (glucosamine) 3-0 sulfot 50
448041 AW292769 Hs 206228 ESTs 50
451244 AW008798 Hs 343877 hypothetical protein FLJ20039 50
443180 R15875 Hε 258576 claudin 12 49
414422 AA147224 Hε 249195 Homeo box A13 49
418866 T65754 gb yd 1c07 s1 Stratagene lung (937210) H 49
420851 AA281062 Hε 29493 hypothetical protein FLJ20142 49
428715 AW293716 Hε 53126 ESTs 49
435937 AA830893 Hε 119769 ESTs 48
435136 R27299 Hs 10172 ESTs 48
438132 AA907076 Hs 122060 ESTs 48
447058 AI939456 Hs 160870 ESTs 48
419187 AA234852 Hs 4693 ESTs 48
433523 H29882 ESTs 48
420871 AA702972 Hs 65300 ESTs 48
450317 AI692689 gb wd86g05 x1 NCI_CGAP_Lu24 Homo sapienε 48
453843 D25215 Hε 35804 hect domain and RLD 3 48
430172 AA468591 Hε 161889 ESTs 48
431657 AI345227 Hε 105448 ESTε, Weakly similar to B34087 hypotheti 47
452843 AI796769 Hε 208320 ESTs 47
458229 AI929602 Hε 177 phosphatidylinositol glycan, class H 47
420954 AA282074 Hs 237323 N xetylglueosamme phosphate mutaεe 47
452031 AA741314 Hε 865 RAP1A member of RAS oncogene family 47
440354 AA889386 Hε 125468 ESTε 47
427212 AW293849 Hε 58279 ESTs, Weakly similar to ALU7.HUMAN ALU S 47
443361 AI792628 Hε 133273 ESTs 46
409731 AA125985 Hε 56145 thymosm, beta, identified in neuroblaεt 46
420026 AI831190 Hε 166676 ESTs 46
450330 AW500775 Hε 24817 hypothetical protein FLJ20136 46
415788 AW628686 Hε 78851 KIAA0217 protein 46
417173 U61397 Hs 81424 ubiquitm-like 1 (εentπn) 46
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 46
434408 AI031771 Hs 132586 ESTs 46
454024 AA993527 Hs 293907 hypothetical protein FLJ23403 46
447805 AW627932 Hs 302421 gemιn4 46
438875 AA827640 Hs 189059 ESTs 46
419511 AA429750 Hs 75113 general transcnption fxtor IIIA 46
445242 BE156478 Hs 21108 ESTs, Weakly similar to ALULHUMAN ALU S 46
428218 AA424266 Hs 123642 EphA3 46
452277 AL049013 Hs 28783 KIAA1223 protein 46
418836 AI655499 Hs 161712 ESTs 45
417601 NM 014735 Hs 82292 KIAA0215 gene product 45
430697 AA484207 Hs 211867 ESTs 45
430701 AI760833 Hs 293971 ESTε 45
437252 AI433833 Hε 164159 ESTε, Weakly similar to ALU1 HUMAN ALU S 45
407204 R41933 Hs 140237 ESTs, Weakly similar to ALU1 HUMAN ALU S 45
420133 AA426117 Hs 155543 ESTs 45
431740 N75450 Hs 183412 ESTs, Moderately similar to AF116721 67 45
439752 T78968 Hs 14411 ESTs 45
447816 NM 007233 Hs 274329 TP53 target gene 1 45
431060 AF039307 Hε 249171 homx box A11 45
445372 N36417 Hs 144928 ESTs 45
452055 A1377431 Hs 141693 hypothetical protein MGC10858 45
416602 NM 006159 Hε 79389 nel (chicken) like 2 44
418019 R68911 Hs 176275 ESTs 44
423352 AA324808 Hs 193576 ESTs 44
438042 AW296971 Hs 180610 ESTs 44
452978 AA029994 Hs 61523 ESTs 44
412643 AW971239 Hs 136433 ESTs 44
417412 X16896 Hs 82112 interleukin 1 rxeptor, type I 44
445210 H09323 Hε 27133 ESTs 44
416706 AA314676 Hs 288945 hypothetical protein FLJ13448 44
420608 BE548277 Hs 103104 ESTs 44
428249 AA130914 Hs 183291 zinc finger protem 268 44
442242 AV647908 Hs 90424 Homo sapiens cDNA FU23285 fis, clone H 44
444030 AW021254 Hs 135055 ESTε 44
435655 AW105663 Hs 6947 HSPC069 protein 44
400533 ENSP00000209376* PRED65 protein (Fragmeπ 44
435285 AW272603 Hs 266134 ESTε 44
450216 AA873345 Hs 60226 Homo εapiens, clone IMAGE 3621638, mRNA, 43
432960 AW150945 Hs 144758 ESTε 43
459527 AW977556 Hs 291735 ESTε, Weakly similar to I78885 seπne/th 43
426413 AA377823 gb EST90805 Synovial sarcoma Homo sapien 43
430535 AW968485 gb EST380561 MAGE resequences, MAGJ Homo 43 416312 W02640 Hs 16247 ESTε, Weakly εimilar to 2004399A chromos 43
454159 AW968065 Hs 44143 polybromo 1 43
435176 AA744875 Hs 189413 ESTε 43
451061 AW291487 Hs 213659 ESTs, Weakly similar to Kl AA1357 protein 43
407910 AA650274 Hs 41296 fibronectin leucine rich transmembrane p 43
420111 AA255652 gb zs21h11 r1 NCI.CGAP.GCB1 Homo sapiens 43
420757 X78592 Hs 99915 androgen receptor (dihydrotestosterone r 43
459045 N69101 Hs 40730 ESTs 43
405348 C7001664 gι|12698061 |dbj|BAB21849 1| (AB 43
422906 U80773 Hs 121580 Human EST clone 42944 mariner transposoπ 43
449603 AI655662 Hs 197698 ESTs 43
409705 M37762 Hs 56023 brain derived neurotrophic fxtor 43
423782 AI472209 Hs 323117 ESTε 43
432887 AI926047 Hs 162859 ESTε 43
420905 AA521307 Hs 186651 ESTε 42
416814 AW192307 Hs 80042 dolichyl P-Glc Man9GlcNAc2-PP-doIιchylgl 42
427908 AA417272 Hs 24122 ESTε 42
432765 AJ003429 gb AJ003429 Selected chromosome 21 cDNA 42
444246 H93281 Hs 10710 hypothetical protein FLJ20417 42
450597 AI701635 Hs 207077 ESTs 42
434022 R18374 Hs 117956 ESTs 42
427761 AA412205 Hs 140996 ESTs 42
433209 AB040907 Hs 278436 KIAA1474 protein 42
413525 BE145899 gb MR0 HT0208 221299-204-b10 HT0208 Homo 42
436679 AI127483 Hs 120451 ESTs, Weakly similar to unnamed protem 42
449655 AI021987 Hs 59970 ESTε 42
440774 AI420611 Hs 153934 ESTε 42
427521 AW973352 Hs 290585 ESTs 42
440594 AW445167 Hs 126036 ESTs 42
458912 AI911066 ESTs 42
410790 AW803357 gb IL2 UM0079 090300 050-A08 UM0079 Homo 41
415245 N59650 Hs 27252 ESTs 41
435743 T66861 Hs 12962 ESTs 41
442786 H50733 Hs 256261 ESTs, Moderately similar to ALU8 HUMAN A 4 1
436714 AA728964 Hs 293399 ESTs 41
423789 AK002084 Hs 132851 hypothetical protein FU11222 41
408177 AI241733 Hs 43871 ESTs 4 1
424200 AA337221 gb EST41944 Endometπal tumor Homo sapie 41
430523 AW451385 Hs 161954 ESTs 41
445206 AI350199 Hs 269990 ESTs 41
452335 AW188944 Hs 61272 ESTs 41
438431 AW207860 Hs 293116 ESTs 41
449907 AA004825 Hε 103281 ESTs 41
430487 D87742 Hs 241552 KIAA0268 protein 41
448152 AI741053 Hs 170770 ESTs 41
448515 H68441 Hs 13528 hypothetical protein FLJ14054 41
423242 AL039402 Hs 125783 DEME-6 protein 41
412715 NM.000947 Hs 74519 pπmase, polypeptide 2A (58kD) 41
400746 Target Exon 41
413081 BE064415 gb RC4-BT0311 -241199-012-b03 BT0311 Homo 41
446416 AV658299 Hs 163959 ESTs 41
451640 AA195601 Hs 26771 Human DNA sequence from clone 747H23 on 41
427203 AW629517 Hs 244855 ESTs 40
440840 AW629666 ESTs, Weakly similar to S64054 hypotheti 40
442338 AI761976 Hs 156080 ESTs 40
446307 T50083 Hs 22247 ESTε 40
455276 BE176479 gb RC3-HT0585-160300-022-b09 HT0585 Homo 40
415861 Z43123 Hs 144513 ESTε 40
418259 AA215404 ESTε 40
418818 AA228899 Hs 101307 Homo εapienε HUT11 protein mRNA, partial 40
432229 AW290976 Hs 143587 ESTs 40
418310 AA814100 Hs 86693 ESTs 40
416760 H85182 Hs 191327 ESTs, Highly similar to KIAA1102 protein 40
419083 AI479560 Hε 98613 Homo sapiens cDNA FU 12292 fis, clone MA 40
421312 AA824627 Hε 291670 ESTs 40
448131 AI675054 Hε 200481 ESTs 40
439731 AI953135 Hε 45140 hypothetical protein FLJ14084 40
418243 W51873 Hs 171857 Homo sapiens testis protein mRNA, partia 40
434072 H70854 Hs 283059 Homo sapienε PRO1082 mRNA, complete eds 40
434844 AF157116 Hs 22350 hypothetical protein LOC56757 40
452221 C21322 Hs 288057 hypothetical protein FLJ22242 40
432697 AW975050 Hs 293892 ESTs, Weakly similar to ALU4 HUMAN ALU S 40
446354 AW449650 Hs 346335 ESTs 40
447072 D61594 Hs 17279 tyrosylprotein sulfolranεferaεe 1 40
417333 AL157545 Hs 173179 bromodomaiπ and PHD finger containing, 3 40
441568 AI733322 Hs 127176 ESTε 40
441736 AW292779 Hs 8182 ESTε 40
457498 AI732230 Hs 191737 ESTs 39
433234 AB040928 Hs 65366 KIAA1495 protein 39
434222 AF119886 Hs 283941 Homo sapienε PR02591 mRNA, complete eds 39
448568 AA149121 Hs 71947 ESTs 39
415068 Z19448 Hs 131887 ESTs, Weakly similar to T24396 hypotheti 39
424940 AA985308 Hε 283902 ESTs 39 416288 H51299 gb yp07c06 s1 Soareε breast 3NbHBst Homo 39
420301 AA767526 Hs 22030 paired box gene 5 (B-cell lineage specif 39
429066 AA868555 Hs 178222 ESTε 39
435878 R08330 Hs 20152 ESTε 39
446862 AV660697 Hs 282700 ESTε 39
447530 AW192063 Hs 248865 ESTs, Moderately similar to JC5238 galae 39
452619 AW298597 Hs 61884 Homo sapienε, clone IMAGE 4298026, mRNA, 39
401403 Target Exon 39
448779 BE042877 Hs 177135 ESTε 39
420533 AI809510 Hs 118971 ESTs 39
411084 T18987 Hs 125472 ESTs, Moderately similarto KIAA0877 pro 39
419629 AB020695 Hs 91662 KIAA0888 protein 39
423453 AW450737 Hs 128791 CGI-09 protein 39
434833 AF156548 Hs 192969 ESTs, Weakly similar to AT1 AJHUMAN POTEN 39
455646 BE064420 gb RC4-BT0311-241199 012-c08 BT0311 Homo 39
411479 AW848047 gb IL3-CT0214-291299-052-A12 CT0214 Homo 39
419038 AW134924 Hs 190325 ESTs 39
421129 BE439899 Hs 89271 ESTs 39
424332 AA338919 Hs 101615 ESTs 39
441766 R53790 Hs 23294 hypothetical protein FLJ 14393 39
447033 AI357412 Hs 157601 ESTs 39
439306 BE220199 WD40 protein Cιao1 38
410352 AW969725 Hs 150444 KIAA0373 gene product 38
407961 AW672939 Hs 41694 origin recognition complex, subunit 2 (y 38
410252 AW821182 Hs 61418 microfibrillar-assxiated protein 1 38
439560 BE565647 Hε 74899 hypothetical protein FU12820 38
440450 AI333129 Hs 156147 ESTs 38
458611 AI268407 Hs 211458 DC-spxific transmembrane protein 38
419589 AW973708 Hs 201925 Homo sapiens cDNA FLJ13446 fis, clone PL 38
431576 M76665 Hs 275215 hydroxysteroid (11-beta) dehydrogenase 1 38
447280 BE617907 Hs 97635 ESTs 38
438379 N23018 Hs 171391 C-terminal binding protein 2 38
416009 Z43062 gb HSC12E041 normalized infant brain cDN 38
416534 H69043 Hs 224961 Homo sapiens cDNA FLJ14366 fis, clone HE 38
423044 AA320829 Hs 97266 protocadhenn 18 38
424701 NM 005923 Hs 151988 mitogen-xtivated protein kinase kinase 38
433507 AI817336 Hs 191791 ESTs 38
437718 AI927288 Hs 196779 ESTs 38
419831 AW448930 Hs5415 ESTs 38
424830 AW270580 Hε 189311 ESTs, Weakly similarto putative p150 [H 38
426981 AL044675 Hs 173081 KIAA0530 protein 38
431447 AA505138 Hs 291341 ESTs 38
435932 W03928 Hs 114524 ESTs 38
442447 AA999723 Hs 129607 ESTs 38
403242 Target Exon 38
433908 AW298141 Hs 157975 ESTs 38
452323 W44356 Hs 292812 ESTs, Weakly similar to T33468 hypotheti 37
412095 AI624707 Hs 5921 Homo sapienε cDNA FLJ21592 fiε, clone C 37
418759 AA227879 Hs 187621 ESTε 37
422299 AK000181 Hs 114556 hypothetical protein FLJ20174 37
452462 BE173515 gb RC2-HT0560-210200-012403 HT0560 Homo 37
423096 AA732684 Hs 278428 progestin induced protein 37
454037 AW998716 gb PM4-BN0067-250300-002411 BN0067 Homo 37
428055 AA420564 Hs 101760 ESTs 37
447785 AL041765 Hs 340375 ESTε 37
451746 M86178 Hs 311258 ESTε 37
453293 AA382267 Hs 10653 ESTs 37
436671 AW137159 Hs 146151 ESTs 37
407437 AF220264 gb Homo sapienε MOST-1 mRNA, complete cd 37
408418 AW963897 Hε 44743 KIAA1435 protein 37
420092 AA814043 Hε 88045 ESTs 37
446947 AF146747 Hε 232165 polycythemia rubra vera 1 , cell surfxe 37
441865 AA384726 Hε 5722 hypothetical protein FU23316 37
419875 AA853410 Hs 93557 proenkephalm 37
431231 AA653552 Hs 116532 ESTs 37
418348 AI537167 Hε 96322 hypothetical protein FLJ23560 37
419261 X07876 Hε 89791 wmgleεε-type MMTV integration site fami 37
422899 D16471 Hs 121571 Human mRNA, Xq terminal portion 37
429163 AA884766 gb am20a10 s1 Soares NFL T_GBC_S1 Homo s 37
439075 AF085933 Hs 292620 ESTs 37
440947 AA910403 ESTs 37
404561 tπchorhmophalangeal εyndrome I gene (T 36
430096 U91935 Hs 233321 Retina-derived POU-domam factor-1 36
430320 BE245290 Hε 239218 uncharxteπzed hypothalamuε protem HCD 36
444794 AI419991 Hε 145225 ESTs 36
426991 AK001536 Homo εapieπε cDNA FLJ10674 fis, clone NT 36
431316 AA502663 Hε 145037 ESTs 36
414178 AW957372 Hε 46791 ESTs, Weakly similar to I38022 hypolheti 36
450630 AA010429 Hs 191939 ESTs 36
411067 AI681006 Hs 71721 ESTs 36
436326 BE085236 aldo-keto redudase family 1 , member B1 36
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of 36
423590 AW952412 Hs 65874 ESTs, Weakly similar to A40348 Elav/Sex- 36 430376 AW292053 Hs 12532 chromosome 1 open reading frame 21 36
451193 N29850 Hs 44098 ESTs 36
416239 AL038450 Hs 48948 ESTs 36
444190 AI878918 Hs 10526 cyεteine and glycine nch protein 2 36
407902 AL117474 Hs 41181 Homo εapienε mRNA, cDNA DKFZp727C191 (fr 36
423349 AF010258 Hε 127428 homeo box A9 36
426917 AA913814 Hs 172854 DKFZP586B0923 protein 36
429430 AI381837 Hs 155335 ESTε 36
433563 AI732637 Hs 277901 ESTε 36
425465 L18964 Hs 1904 protein kinaεe C, iota 35
452498 AK000101 Hs 29700 hypothetical protein FLJ20094 35
401132 C12000517* gι|4758712|ref|NP 004659 1| a 35
421105 AA766501 Hs 125113 ESTε 35
435177 AI018174 Hs 42936 ESTε 35
449343 AI151418 protein phosphatase 3 (formeriy 2B), cat 35
457653 AI820719 Hs 154662 DnaJ (Hsp40) homolog, subfamily A, membe 35
419563 AA526235 Hs 193162 Homo sapiens cDNA FLJ11983 fis, clone HE 35
419994 AA282881 Hs 190057 ESTε 35
427304 AA761526 Hs 163853 ESTε 35
434763 AA648618 gb ns07a11 r1 NCI CGAP Ew1 Homo sapienε 35
447497 AW167254 Hs 205722 ESTε 35
449988 AW372068 Hs 201420 ESTε, Moderately similarto ALU7.HUMAN A 35
422321 AA906427 Hs 181035 hypothetical protein MGC11296 35
418723 AA504428 Hs 10487 Homo sapienε, clone IMAGE 3954132, mRNA, 35
438680 AA906121 Hs 173421 ESTε 35
452903 AI953425 Hs 345291 ESTε, Weakly similar to I38022 hypotheti 35
443273 AI042063 Hs 132156 ESTs 35
403510 Target Exon 35
435681 AA694192 Hs 148979 ESTs 35
451722 H86374 Hs 40861 ESTs 35
435981 H74319 Hs 188620 ESTs 35
449845 AW971183 Hs 9683 DnaJ (Hεp40) homolog, subfamily C, membe 35
436024 AI800041 Hs 190555 ESTs 35
429643 AA455889 Hs 167279 FYVE-finger containing Rab5 effector pro 35
443324 R44013 Hs 164225 ESTs 35
458332 AI000341 Hs 220491 ESTs 35
435688 H72286 Hs 128387 ESTs 34
435047 AA454985 Hs 54973 cadhenn like protein VR20 34
432606 NM 002104 Hs 3066 granzyme K (senne protease, granzyme 3, 34
409047 AW961434 Hs 31539 ESTs 34
404848 ENSP00000240769* BG15303 1 (similar to C 34
412494 AL133900 Hs 792 ADP-πbosylafion fxtor domain protein 1 34
417435 NM 005181 Hs 82129 carbonic anhydrase III, muscle spxific 34
430403 AF039390 Hs 241382 tumor necrosiε factor (ligand) εuperfami 34
436340 R42246 Hs 21606 ESTs 34
441596 AA939300 Hs 206768 ESTs 34
442231 W02434 Hs 222413 ESTs 34
447124 AW976438 Hs 17428 RBP1-lιke protein 34
449517 AW500106 Hs 23643 seπne/threonine protein kinaεe MASK 34
450297 AW901347 Hs 38592 hypothetical protein FU23342 34
453682 T79703 gb yd71e08 r1 Soareε fetal liver εpleen 34
456995 T89832 Hs 170278 ESTε 34
444324 AI301330 Hs 143838 ESTε 34
400379 NM.018432 Homo εapienε ovanan cancer related prot 34
419964 AA811657 Hs 220913 ESTε 34
424026 AI798295 Hs 137576 nboεomal protein L34 pεeudogene 1 34
427033 AI457449 Hs 192817 ESTε 34
453942 AW190920 Hε 19928 hypothetical protem SP329 34
431421 AW969118 Hε 108144 ESTε, Weakly similar to unnamed protein 34
408784 AW971350 Hε 63386 ESTs 34
420184 AA188408 Hs 95665 hypothetical protein 34
420721 AA927802 Hs 159471 ZAP3 protein 34
422728 AW937826 Hε 103262 ESTs, Weakly similar to ZN91.HUMAN ZINC 34
436703 AW880614 Hs 146381 RNA binding motif protein, X chromosome 34
429165 AW009886 Hs 118258 prostate cancer asεxiated protein 1 34
427674 NM 003528 Hs 2178 H2B hiεtone family, member Q 34
412505 AA974491 Hs 21734 ESTs 34
431408 AA504757 Hs 105738 ESTs 34
438801 AA825971 Hs 124284 ESTs 34
445432 AV653771 gb AV653771 GLC Homo sapiens cDNA clone 34
418575 AA225313 Hs 222886 ESTs, Weakly similar to TRHY HUMAN TRICH 33
436345 AA873008 Hs 121572 ESTε 33
423023 N50128 Hs 173400 ESTε 33
427615 BE410107 Hs 179817 CGI-82 protein 33
429588 AI080271 Hs 134533 ESTε 33
400362 AF068294 Hs 272414 Homo εapiens HDCMB45P mRNA, partial eds 33
425523 AB007948 Hs 158244 KIAA0479 protein 33
426237 AK001104 Hs 168241 hypothetical protein FLJ10242 33
427473 AW274439 Hs 252709 ESTs 33
434520 AA205273 Hs 177011 hypothetical protein 33
447282 AI989963 Hs 197505 ESTs 33
433554 AW957666 Hs 8108 disabled (Drosophila) homolog 1 33
414818 BE541217 Hε 23606 ESTs 33 418985 AI042330 Hs 87128 hypothetical protein FLJ23309 33
436854 AA749167 Hε 173911 ESTs 33
430865 AI073424 Hs 5232 HSPC125 protein 33
447182 BE241868 Hs 17585 KIAA0801 gene product 33
423645 AI215632 Hs 147487 ESTs 33
429227 AI961456 Hs 21275 hypothetical protein FLJ 11011 33
411928 AA888624 Hs 197289 rab3 GTPase activating protein, non cata 33
418051 AW192535 Hs 19479 ESTε 33
418719 AW975590 Hε 161707 ESTs 33
437714 AA766346 Hs 293242 ESTs 33
455710 BE072049 gb PM4-BT0532 170100 004406 BT0532 Homo 33
421590 AF004715 Hs 105940 jerky (mouse) homolog like 33
445707 AI248720 Hs 114390 ESTs 33
411436 AW846433 gb QV0 CT0179 070300-143 b02 CT0179 Homo 33
426657 NM 015865 Hs 171731 solute carrier family 14 (urea transport 33
423412 AFΪ09300 prostate cancer associated protein 5 33
436962 AW377314 Hs 5364 DKFZP564I052 protein 33
415319 AA659823 Hs 34955 Homo sapiens cDNA FLJ13485 fis, clone PL 33
429318 AW861930 Hs 102500 hypothetical protein dJ511E16 2 33
433213 AW665130 Hs 137190 ESTs 33
453973 AI291895 Hs 61993 ESTs, Weakly similar to ALULHUMAN ALU S 33
418245 AA088767 Hs 83883 tranεmembrane, prostate androgen induced 32
428043 T92248 Hs 2240 uteroglobin 32
407385 AA610150 Hs 272072 ESTs, Weakly similar to I38022 hypotheti 32
423595 R82826 Hs 220702 ESTs 32
407021 U52077 gb Human maπnerl traπsposase gene, comp 32
418986 AI123555 Hs 81796 ESTs 32
438118 AW753311 Hs 346690 ESTs 32
447516 W05355 Hs 102971 hypothetical protein FLJ14751 32
449570 AA001793 gb zh86c06 r1 Soares.fetal.liver.spleeπ. 32
450687 AA495800 gb zw05b07 ε 1 Soareε NhHMPu SI Homo εapi 3 2
425657 T89839 Hs 119471 ESTε 32
459646 AW883968 Hs 321190 gb QV3 OT0063-290300-135-C04 OT0063 Homo 32
408480 AI350337 Hs 164568 fibroblast growth fxtor 7 (keratiπocyte 32
451025 AW028689 Hs 301985 ESTs 32
401416 C14000338' gι|7459502|pιr||S74665 outer 32
421928 AF013758 Hs 109643 polyadeπylate binding protein interxtin 32
454860 AW835767 gb QV4-LT0016-240200-110-b08 LT0016 Homo 32
436995 AI160015 Hε 118112 ESTs 32
428736 AK001331 Hε 192662 hypothetical protein FLJ 10469 32
420120 AL049610 Hε 95243 transcription elongation factor A (Sll)- 32
422352 AA766296 Hε 99200 ESTε 32
429037 X81895 Hε 194765 H sapiens GENX-5624 mRNA, 3' UTR 32
432625 AI243596 Hε 94830 ESTε, Moderately similar to T03094 A-km 32
445218 T79971 Hε 12432 Homo sapiens clone 24407 mRNA sequence 32
447597 AI886036 Hε 213675 ESTs 32
437866 AA156781 metallothionein 1E (functional) 32
416882 AI633044 tryptophanyl tRNA synthetaεe 2 (mitxhon 32
410870 U81599 Hs 66731 homx box B13 32
438899 AF085833 Hs 135624 ESTs 32
415862 R51034 Hs 144513 ESTs 32
420969 AI636310 Hs 28310 ESTs 32
415467 R60891 Hs 260274 ESTs 32
412666 AL080116 Hs 74420 oπgin recognition complex, subunit 3 (y 32
417380 T06809 Hs 332086 ESTs 32
418319 AW611703 Hs 190173 ESTs, Weakly similar to A46010 X-lmked 32
419088 AI538323 Hs 52620 integπn, beta 8 32
422165 AL041199 Hs 1481 histidine dxarboxylase 32
448044 AI458682 gb tk13e01 x1 NCI CGAP Lu24 Homo εapienε 32
452862 AW378065 Hs 8687 ESTε 32
405548 Target Exon 3 1
439584 AA838114 Hs 221612 ESTε 3 1
419839 U24577 Hs 93304 phospholipase A2, group VII (platelet x 3 1
427359 AW020782 Hs 79881 Homo sapiens cDNA FU23006 fis, clone L 3 1
429569 AA454993 Hs 138343 ESTs, Weakly similar to I78885 seπne/th 31
434512 AW139932 Hs 188941 ESTs 31
452102 U04343 Hs 27954 CD86 antigen (CD28 antigen ligand 2, B7- 3 1
425856 AA364908 Hs 98927 hypothetical protein FLJ 13993 3 1
416836 D54745 Hs 80247 cholecystokinm 3 1
432589 AL135725 Hs 131708 ESTε 31
420512 AA262886 Hs 143817 ESTε 31
417206 AA291183 Hs 81648 hypothetical protein FLJ 11021 similar to 3 1
410821 AI114811 Hs 92526 ESTs, Weakly similar to T00365 hypotheti 3 1
423855 AA331761 Hs 254859 ESTs 3 1
425905 AB032959 Hs 318584 novel C3HC4 type Zinc finger (ring finge 31
427773 AA412290 Hs 98124 ESTs 31
441817 AW969706 Hs 293332 ESTε 3 1
456660 AA909249 Hs 112282 εolute carrier family 30 (zinc transport 31
421823 N40850 Hs 28625 ESTs 3 1
416812 H91010 Hs 44940 ESTs 3 1
445784 AI253155 Hs 146065 ESTs 3 1
434384 AA631910 Hs 162849 ESTs 3 1
416140 AI918035 Hs 301198 roundabout (axoπ guidance rxeptor, Dros 3 1 407426 AF129533 gb Homo sapienε F box protein Fbl3b (FBL 3 1
416423 H54375 Hs 268921 ESTs 3 1
418037 AI990212 Hs 86447 ESTε 31
419197 N48921 Hs 27441 KIAA1615 protein 3 1
420179 N74530 Hs 21168 ESTε 3 1
433610 AA806822 Hs 112547 ESTε 3 1
436295 N73895 gb za62d06 ε1 Soareε fetal liver spleen 3 1
444800 AW119071 Hs 153287 ESTs 31
418858 AW961605 Hs 21145 hypothetical protein RG083M052 3 1
446469 BE094848 Hs 15113 ho ogentisate 1,2-dιoxygenase (homogenti 3 1
431992 NM.002742 Hs 2891 protein kinase C, mu 3 1
405510 ENSP00000233779* Hypothetical 680 kDa p 31
407349 AA825449 Hs 83332 Homo sapiens cDNA FLJ22437 fis, clone H 31
410869 AW808361 gb MR1-ST0111-111099003404 ST0111 Homo 31
425354 U62027 Hs 155935 complement component 3a receptor 1 3 1
425480 AB023198 Hs 158135 KIAA0981 protein 31
441492 AI149998 Hs 146346 ESTs 3 1
447078 AW885727 Hs 9914 ESTs 31
459324 AW080953 gb xc28c12 x1 NCI CGAP_Co18 Homo εapienε 31
433852 AI378329 Hε 126629 ESTs 30
448658 H71739 Hε 200227 ESTs, Moderately similar to A53959 throm 30
452242 R50956 Hε 159993 gycosyltransferase 30
424690 BE538356 Hε 151777 eukaryotic translation initiation factor 30
405264 NM_030813* Homo sapienε εuppreεεor of po 30
407253 AA411175 Hε 141939 ESTε, Moderately similar to S65657 alpha 30
452234 AW084176 Hε 223296 ESTs, Weakly similar to I38022 hypotheti 30
434497 AI821803 Hε 136580 ESTs 30
420355 AW968263 Hε 123126 ESTs 30
403481 Target Exon 30
412988 BE046680 gb hn42h03 x1 NCI.CGAP.RDF2 Homo sapiens 30
452679 Z42387 Hε 83883 transmembrane, prostate androgen induced 30
416642 T96118 Hε 226313 ESTs 30
418948 AI217097 gb qd43h07 1 Soares fetal heart NbHH19W 30
426174 AA547959 Hε 115838 ESTs 30
430459 BE178539 Hs 278634 ESTs 30
439182 AF086030 Hs 21621 hypothetical protein DKFZp762O076 30
446258 AI283476 Hs 263478 ESTs 30
448686 AA158659 Hs 334712 hypothetical protein FU 14744 30
453455 AA063553 Hs 221931 ESTs, Weakly similar to JC1087 RNA helic 30
414441 AA234759 Hs 132950 ESTs 30
427302 AA400540 Hs 135282 Homo sapiens cDNA FU11554 fis, clone HE 30
437048 AA743240 Hs 91582 ESTs 30
450963 AI864668 Hs 48832 ESTs 30
432336 NM_002759 Hs 274382 protein kinase, terferon-inducible dou 30
459535 AV654907 gb AV654907 GLC Homo sapiens cDNA clone 30
448734 BE614070 Hs 326416 Homo sapienε mRNA, cDNA DKFZp564H1916 (f 30
451468 AW503398 Hs 293663 ESTε, Moderately similar to I38022 hypot 30
407829 AA045084 Hs 29725 hypothetical protein FU13197 30
420407 AA814732 Hs 145010 lipopolysxcaπde-εpxifio reεponse 5-lι 30
426743 AA383833 Hs 245022 ESTs 30
442326 H92962 Hs 124813 hypothetical protein MGC14817 30
449913 AA004696 Hs 333016 ESTs 30
454096 AW062757 gb CM0-CT0103-120899-O37-g07 CT0103 Homo 30
437323 AA371145 Hs 194397 leptm receptor 30
407137 T97307 gb ye53h05 s1 Soareε fetal liver εpleen 30
450580 N40087 ESTε 30
429084 AJ001443 Hs 195614 splicing fxtor 3b, subunit 3, 130kD 30
418365 AW014345 Hs 161690 ESTε 30
423784 AK000039 Hs 132826 Homo εapienε cDNA FU14913 fis, clone PL 30
435677 AA694142 Hs 293726 ESTs, Weakly similar to TSGA RAT TESTIS 30
414951 AW794931 Hs 100861 hypothetical protein FLJ14600 30
418819 AA228776 Hs 191721 ESTs 30
428634 AA811845 Hs 106290 Kelch motif containing protein 30
431869 AA521136 Hs 190176 ESTs 30
435008 AF150262 Hs 162898 ESTs 30
448880 AW205507 Hs 32360 ESTs, Highly similar to I38587 retroviru 30
451391 AA017410 Hs 40568 ESTs 30
452959 AI933416 Hs 189674 ESTs 30
TABLE 64B
Pkey Unique Eoε probeεet identifier number
CAT number Gene cluster number Accession Genbank xcesεion numbers
Pkey CAT Number
410790 1221131.1 AW803357 AW803423 AW812233 R06814
410869 1225123.1 AW808361 AW808404 AW808386 AW808594 AW808654 AW808813 AW808551 AW808676 AW808350 AW808406 AW808694 AW808934
AW808829 AW808385 AW808422 AW808401 AW808409 AW808760 AW808863 AW808521 AW808539 AW808609 AW808472 AW808739
AW808704 AW808558 AW808714 AW808420 AW8
411436 1245660.1 AW846433 AW846159 AW846377 AW846528 411479 1247077.1 AW848047 AW848202 AW848631 AW848142 AW848702 AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069
AW848905 AW848214
412988 13421501 BE046680 BE046738 BE044958
413081 13485631 BE064415 BE064430 BE064448
413525 13746351 BE145899 BE145848 BE145849 BE145853 BE145927 BE145925
415989 1564541 AI267700 AI720344 AA191424 AI023543 AI469633 AA172056 AW958465 AA172236 AW953397 AA355086
416009 15663791 Z43062 R13213 H14422
416288 15859831 H51299 H44619 H46391 R86024 H51892 T72744
416882 162718.1 A1633044 AW016212 AW241143 AA769058 R43272 AW068958 AA210918 AA293774 AI748815 AI763294 AI333114 AI277384 AI088297 AI468477
AI824624 AW189606 AI631751 Z40749 AI984673 AI671316 AA189024 AW235412 BE178426 R24677 R40635 H05100 R40597
418259 1733881 AA215404 AI990909 BE464132 AW271459 N74332 AI262061
418866 1797881 T65754 AA229857 AA229658
418948 1808081 AI217097 AW886090 W38035 W38792 AA232835 AW936043
419536 1856881 AA603305 AA244095 AA244183
420111 1907551 AA255652 AA280911 AW967920 AA262684
420352 1929791 BE258835 AW968316 AA258918 AW843305 R14744 AI580388 BE071923 R36280
423412 228001 1 AF109300 AI299378 AI202654
424200 2365951 AA337221 AA336756 AW966196
426413 2666501 AA377823 AW954494 AI022688
426503 2682831 AA380153 AA380233 AW963529
426991 274151 AK001536 AA191092 AW510354 AI554256 AL353968 AA134266
428002 2856021 AA418703 AA418711 BE071915 BE071920 BE071912
428342 290035.2 AI739168 AA426249 AI199636 AW505198 AW977291 AA824583 AA883419 AA724079 AI015524 AI377728 AW293682 AI928140 AA731438
AI092404 AI085630 AA731340
429163 3005431 AA884766 AW974271 AA592975AA447312
429220 3013841 AW207206 AW341473 AA448195 AI951341
430535 3196431 AW968485 AW968670 AA480922 BE350425
432600 3509591 AI821085 AW973464 AA554802 A1821831 AA657438 AA640756 AA650339
432765 3539071 AJ003429 AJ003367 AA564825
433523 3688731 H29882 AW665533 AW149901 AI572917 AA598500 AI686466 AI336390 AW864390 AW864320
434763 3928471 AA648618 A 974389 H51771
436295 417331 N73895AJ001872
436326 417952 BE085236 BE085317 X04236 AA577934 AA578392 AA502836 AA595852 AA578258 AW270791 AA507151 AA559152 T57040 BE503281
AW593405 AI825755 AI350499 AI655710 AI972281 AI654949 BE073961 BE073962 BE041399 AW750214 AA228488 BE074016 AI908706
AW270601 AW873282
437866 44433.2 AA156781 AW293839 U52054AA024963 AA778446 BE073977 AW444904AW602574 BE164040 BE164012 BE163972 BE163974 BE163992
AA837481 AW468444 BE185091 AW468002 AA687333 AA811830 AA581806 AI866686 AI572124 AA043777 AA040926 D20160 AI536733
AA812489 AW874142 AI47188
439092 4685541 AA830149 AW978407 M85983 AW503637
439306 470881 BE220199 W01813 AF086118 N70760 BE221405
440840 50357.2 AW629666 AW959831 AW205739 BE620243 AA412367 AW300025 AW051920 AI288591 AW236114 AI302852 AI038548 AA534496 AI797207
AA921877
440947 5059041 AA910403 AI815593 W58361 AW162520 AI816550
442481 5435881 N99828 BE079873 AH 10738 AF074645
445432 639431 AV653771 BE089370
448044 7471961 A1458682 H24240 R14537 R18426 AW867082
449343 80517.2 AI151418 W60401 AW631238 AI346936 AA862855W60310 N72501 H90060 BE150445AW380821 AI540906 C04881 W03542 AA641764 H97053
AW889353 AA521308 AA001203 W92828 AI207798 AA746655 R78710 W24617 AA024605 C01747 AW173095 W61229 W92685 AA742467
H00789 R76925 AW1828
449570 810181 AA001793 AA001871
449625 8113.1 NM 014253 AF100772 BE088769 AL022718 BE161779 AW863569 BE161640 AL039060 BE168542 AW296554 AA323193 AA235370 AW779760
N48674 AI375997 R45432 D59344 AI203107 F07491 R35360 R25094 AI913631 AI498402 T61382 AI016320 N45526 T61415 AA331486
450317 8319561 AI692689 R14223 R18395
450580 83929.1 N40087 H12925 AA460779 AA096372 BE160847 AW816890 AW816893 AW816577 AW816891 AW816882 AW816868 AW816889 AW816940
AW816892 AW816941 AW816578 AA029183 T83320 H86850 AA010295 BE160823 Z25353 AA150883 AW887764 AW023806 AW022095
AA164518 AA730973 W00417 W65303
450582 839331 AI339732AA010300AW515041 AA768334 N29860AA425874AA425118 AA865829 AW936878
450687 84327.1 AA495800 AA495737 AA010736 AA654716 AA640726
452462 9185801 BE173515 BE173560 A1902860
453682 9774541 T79703 T96307 AL079725
454037 9962871 AW998716 AW022148 N68020
454096 10074491 AW062757 AW176890 AW062758 AW176895 AW176869 AW176900 AW176897 AW176928 AW176868 AW176892
454171 10492401 AW854832 AW854798 AW854857 AW854816 AW854834 AW854817
454457 12072741 AW753456 AW753036 AW854868 AW854862
454860 12377321 AW835767 AW835537 BE160187
454968 12470291 AW849046 AW847956 AW849039 AW847957 AW848279 AW848698 AW849034 AW849033
455276 1272541 1 BE176479 BE176678 BE176357 BE176550 AW886079 BE176676 BE176615 BE176555 BE176489 BE176610 BE176362
455646 13485571 BE064420 BE064435 BE064429 BE064414 BE064400 BE064517
455710 13523681 BE072049 BE069471 BE069489 BE069478 BE069479 BE069492 BE069485 BE072122 BE072124 BE069491 BE069486 BE069464
457374 3287581 AA493662 AW897396 BE154814
458912 8231041 AI911066 AI933734 AI680888 AJ003599
TABLE64C
Pkey Unique number correεpondmg to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 400533 6981826 Minuε 277132-277595
400746 7329328 Minuε 147703 147896
401132 8705350 Minus 85679 85795
401403 7710966 Plus 146180 146294
401416 7452889 Minus 121456 121626
401424 8176894 Plus 24223 24428
403242 7637817 Minus 11297-12511
403481 9965004 Plus 93496 93633
403510 7652047 Plus 61866 62027
403667 6850483 Minus 1344-1442,1545-1697
403696 3135242 Minus 143467-143634
404003 8655948 Pluε 198349 199096
404561 9795980 Minuε 69039 70100
404571 7249169 Minuε 112450-112648
404592 9943965 Minuε 39067-39225
404848 8248647 Minus 23955 2403425143-25264
405264 7329374 Plus 28556-28684
405348 2914717 Minus 43310-43462
405510 7630909 Minus 101028 101174
405548 1532158 Plus 11552-11686
Table 65A lists about 347 genes up regulated in BPH compared to prostate cancer tissues These were selected from 59680 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" BPH to "average" prostate cancer tissues was greater than or equal to 30 The "average" BPH level was set to the 75* percentile amongst BPH tisεueε The "average" proεtate cancer tiεεue level was set to the 85* percentile amongst malignant prostate tisεueε In order to remove geπe-εpxific bxkground levelε of non- εpecific hybridization the 10* percentile value amongst non-malignant body tisεueε was subtrxted from both the numerator and the denominator before the ratio was evaluated
TABLE 65A ABOUT 347 GENES UP-REGULATED IN BENIGN PROSTATIC HYPERPLASIA COMPARED TO PROSTATE CANCER TISSUES
Pkey Unique Eoε probeεet identifier number ExAccn Exemplar Acceεεion number, Genbank acceεεion number UnigenelD Unigene number Unigene Title Unigene gene title _R1 Ratio of BPH tissue to prostate tumor tissue
Pkey ExAccn Unigene ID Unigene Title R1
428134 AA421773 Hs 161008 ESTε 94
446336 AW815036 Hs 151251 ESTs 93
456373 BE247706 Hs 89751 membrane-spanning 4-domams, subfamily A 89
458072 AI890347 Hε 271923 Homo sapienε cDNA FLJ22785 fiε, clone K 88
400533 ENSP00000209376* PRED65 protein (Fragmen 87
418310 AA814100 Hε 86693 ESTε 87
404592 NM 022739* Homo εapieπs E3 ubiquitin tig 81
454457 AW753456 gb QV2-CT0261-261099-011-d11 CT0261 Homo 77
400080 Eos Control 74
459646 AW883968 Hε 321190 gb QV3-OT0063-290300-135-C04 OT0063 Homo 74
420352 BE258835 gb 601117374F1 NIH MGC 16 Homo εapienε c 73
438231 AW594539 Hε 155689 ESTε 73
418387 R18085 gb yg16b12 r1 Soareε infant brain 1NIB H 72
442481 N99828 gb za32c04 r1 Soareε fetal liver spleen 7 1
449249 T52285 Hε 193115 Homo sapienε mRNA for KIAA1764 protein, 70
457653 AI820719 Hs 154662 DnaJ (Hsp40) homolog, subfamily A, membe 69
404967 Target Exon 69
430535 AW968485 gb EST380561 MAGE resequenceε, MAGJ Homo 69
454860 AW835767 gb QV4-LT0016-240200-110 b08 LT0016 Homo 69
423789 AK002084 Hs 132851 hypothetical protein FLJ11222 68
412988 BE046680 gb hn42h03 x1 NCI.CGAP.RDF2 Homo εapienε 68
400440 X83957 Hs 83870 nebulin 66
454171 AW854832 gb QV2-CT0261-201099-011-f05 CT0261 Homo 66
400086 Eos Control 64
440911 AA909536 Hs 143562 ESTs 64
425312 AA354940 Hs 145958 ESTs 64
426140 AF131798 Hs 343768 Homo sapiens clone 25119 mRNA sequence 64
419015 T79262 Hs 14463 ESTε 63
453789 AA628517 Hs 118502 ESTs 62
424940 AA985308 Hs 283902 ESTs 61
403667 Target Exon 61
429014 AI800518 Hs 118158 ESTs 60
417758 U27699 Hs 82535 solute earner family 6 (neurotranεmitte 60
419999 AI760942 Hs 191754 ESTε 60
405348 C7001664gι|12698061|dbj|BAB21849 1| (AB 60
404003 Target Exon 59
453200 AA033832 Hs 212433 ESTs 57
428002 AA418703 gb zv98c03 s1 Soareε NhHMPu S1 Homo sapi 57
432319 AW510770 Hs 128386 ESTs 57
445444 AA380876 Hs 270 plxkstππ homology, Sec7 and coiled/coi 56
443361 AI792628 Hε 133273 ESTε 56
411518 AW850246 gb IL3-CT0219-291099 021-E07 CT0219 Homo 56
439079 AF085937 Hε 38348 ESTε 55
422081 AW136820 Hε 196011 ESTε 55
408197 AA282262 Hs 107410 ESTε, Weakly similar to A46010 X linked 55
423529 T87318 Hs 120411 ESTs 55 436578 AI091435 Hs 134859 ESTs 55
450920 AA011626 Hs 133324 ESTs 55
435072 AW592176 Hs 116932 ESTs 54
414403 AW969551 Hs 76064 πbosomal protein L27a 54
443744 AI084326 Hs 271548 ESTs, Weakly similar to I78885 seπne/th 54
433087 AI720686 Hs 152520 ESTs 53
441916 AA993571 Hs 129075 ESTs 53
414818 BE541217 Hs 23606 ESTs 53
452531 AA429462 Hs 293946 ESTs, Weakly similar to I38022 hypotheti 53
454968 AW849046 gb IL3-CT0214-150300-085-H06 CT0214 Homo 52
415890 H08225 Hs 268712 ESTs 52
408385 AF055634 Hs 44553 uπc5 (C elegans homolog) c 52
437752 AA767376 Hs 291631 ESTε, Moderately similar to S65657 alpha 52
446495 D60923 Hs 153460 ESTs 52
435375 AI733610 Hs 187832 ESTs 52
426748 AL048409 Hs 97177 ESTs, Weakly similar to ALULHUMAN ALU S 52
424994 AW954525 gb EST366595 MAGE resequences, MAGC Homo 52
405321 Target Exon 5 1
416706 AA314676 Hs 288945 hypothetical protein FLJ 13448 51
438206 AA780385 Hs 187885 ESTs 51
445238 AA883971 Hs 187506 ESTs 51
455747 BE074910 gb RC5-BT0580-170300 0214=12 BT0580 Homo 5 1
420533 AI809510 Hs 118971 ESTs 5 1
457374 AA493662 gb nh05d12 s1 NCI CGAP.Thyl Homo εapiens 50
440354 AA889386 Hs 125468 ESTs 50
440388 AI693520 Hs 223000 ESTs 49
421188 AA284658 Hs 261493 ESTε 49
403481 Target Exon 48
438132 AA907076 Hs 122060 ESTε 48
403333 NM.002518* Homo εapieπε neuronal PAS dom 48
450317 AI692689 gb wd86g05 1 NCI CGAP_Lu24 Homo sapiens 48
433597 AA708205 Hs 100343 ESTs 48
430172 AA468591 Hs 161889 ESTs 48
452843 AI796769 Hs 208320 ESTε 47
452031 AA741314 Hs 865 RAP1 A, member of RAS oncogene family 47
427302 AA400540 Hs 135282 Homo εapienε cDNA FLJ11554 fis, clone HE 47
442123 AI697790 Hs 159961 EST 47
438727 AW978756 Hs 205679 ESTs 47
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 46
442160 AI337127 Hs 156325 ESTε 46
442295 AI827248 Hs 224398 Homo εapiens cDNA FLJ 11469 fis, clone HE 46
434589 AF147363 gb Homo sapienε full length insert cDNA 46
404995 ENSP00000251890* Monxytic leukemia zinc 46
422906 U80773 Hs 121580 Human EST clone 42944 mariner transposon 45
405549 C7001976* gι|4758712|reflNP_004659 1| al 45
430697 AA484207 Hs 211867 ESTs 45
443998 AI620661 Hs 296276 ESTs 45
455801 BE140643 gb RC0-HT0015-310599-016 HT0015 Homo sap 45
444800 AW119071 Hs 153287 ESTs 45
403371 Target Exon 45
438431 AW207860 Hs 293116 ESTs 45
421926 AA300591 gb EST13437 Testis tumor Homo sapieπε cD 45
439752 T78968 Hs 14411 ESTε 45
414441 AA234759 Hs 132950 ESTε 45
454665 AW812866 gb RC3-ST0186-300100-017-b03 ST0186 Homo 45
454585 BE069128 gb QV3-BT0379-310100-071 -g06 BT0379 Homo 44
452978 AA029994 Hs 61523 ESTε 44
438042 AW296971 Hs 180610 ESTε 44
418059 AA211586 gb zn56d05 ε1 Stratagene muscle 937209 H 44
451469 NM.014809 Hs 26441 KIAA0319 gene product 44
433072 AI928037 Hs 158832 ESTs 44
443318 AI051603 Hs 133141 ESTs 44
424686 AA345504 gb EST51529 Gall bladder II Homo sapienε 43
416312 W02640 Hs 16247 ESTε, Weakly similar to 2004399A chromos 43
415467 R60891 Hs 260274 ESTs 43
459045 N69101 Hε 40730 ESTs 43
415417 F12038 Hε 140970 ESTs, Weakly similar to ALU6.HUMAN ALU S 43
409111 AL043362 Hε 7984 plxkstπn homology, Sx7 and coiled/coi 43
441620 R59595 Hs 26675 ESTs 42
427908 AA417272 Hs 24122 ESTs 42
432765 AJ003429 gb AJ003429 Selxted chromosome 21 cDNA 42
448108 AW300021 Hs 170685 ESTs 42
436345 AA873008 Hs 121572 ESTs 42
409500 U08098 Hs 54576 sulfotransferase, estrogen-preferring 42
413525 BE145899 gb MR0-HT0208-221299-2044)10 HT0208 Homo 42
403305 NM 006825 transmembrane protein (63kD), endoplasmi 42
436338 W92147 Hs 118394 ESTs 42
427521 AW973352 Hs 290585 ESTs 42
430124 AW204994 Hs 253450 ESTs 42
410790 AW803357 gb IL2-UM0079-090300 050-A08 UM0079 Homo 41
434360 AW015415 Hs 127780 ESTs 41
416385 H54253 Hs 205241 ESTs, Weakly similar to S65657 alpha-1 C- 4 1
442786 H50733 Hs 256261 ESTε, Moderately similar to ALU8_HUMAN A 4 1 445206 AI350199 Hs 269990 ESTs 4 1
424200 AA337221 gb EST41944 Endometπal tumor Homo sapie 4 1
448152 AI741053 Hs 170770 ESTε 4 1
453713 R20640 Hε 79133 cadhenn 8, type 2 41
400746 Target Exon 4 1
413081 BE064415 gb RC4-BT0311-241199-0124)03 BT0311 Homo 4 1
442338 AI761976 Hs 156080 ESTε 40
455388 AW936234 gb QV0-DT0020 090200-106 g05 DT0020 Homo 40
455276 BE176479 gb RC3-HT0585-160300-022-b09 HT0585 Homo 40
421312 AA824627 Hs 291670 ESTε 40
431421 AW969118 Hs 108144 ESTε, Weakly similar to unnamed protein 40
448882 AJ001531 Hs 22404 protease, εeππe, 12 (neurotrypεm, moto 40
441568 AI733322 Hs 127176 ESTs 40
455646 BE064420 gb RC4-BT0311-241199-012-c08 BT0311 Homo 39
424765 AA428211 Hs 284256 hypothetical protein FLJ14033 similar to 39
454024 AA993527 Hs 293907 hypothetical protein FLJ23403 39
453387 AI990741 Hs 252809 ESTs 39
434222 AF119886 Hs 283941 Homo sapienε PR02591 mRNA complete eds 39
454806 AW872430 Hε 273743 ESTs 39
429066 AA868555 Hs 178222 ESTε 39
435878 R08330 Hs 20152 ESTε 39
453055 AW291436 Hs 31917 Homo sapiens, clone MGC 9658, mRNA, comp 39
447530 AW192063 Hs 248865 ESTs, Moderately similar to JC5238 galac 39
407834 AW084991 Hs 26100 ESTs 39
400398 AF137396 Hs 283879 ubiquilm 3 39
421353 AW292857 Hs 255130 ESTs 39
401459 C14000482* gι|9790241|ref|NP_062628 1| S 39
403433 NM.001622 Homo sapiens alpha-2-HS-glycop 39
444911 U06117 Hs 250 xaπthene dehydrogenase 39
436350 AA713661 Hs 121091 ESTs 39
447930 R44574 Hs 107510 ESTs 39
410559 AW754192 gb RC2-CT0321-131299-012-a04 CT0321 Homo 38
452320 AA042873 Hs 160412 ESTs 38
402145 Target Exon 38
458438 AI141520 Hs 151464 ESTa, Weakly similar to ALUC HUMAN «« 38
440450 AI333129 Hs 156147 ESTs 38
437587 AI591222 Hs 72325 Human DNA sequence from clone RP1-187J11 38
416009 Z43062 gb HSC12E041 normalized infant brain cDN 38
434381 AA631834 gb np77h05 s1 NCI_CGAP_Pr2 Homo εapiens 38
416534 H69043 Hs 224961 Homo sapienε cDNA FU14366 fiε, clone HE 38
433523 H29882 ESTs 38
411436 AW846433 gb QV0-CT0179-070300-143-b02 CT0179 Homo 38
424830 AW270580 Hs 189311 ESTs, Weakly similar to putative p150 [H 38
431447 AA505138 Hs 291341 ESTs 38
435932 W03928 Hs 114524 ESTs 38
442447 AA999723 Hs 129607 ESTs 38
419831 AW448930 Hs 5415 ESTs 38
403242 Target Exon 38
455490 AW953477 gb EST365547 MAGE resequenceε, MAGB Homo 38
449264 AI637649 Hs 196105 ESTε 38
443635 AI080230 Hs 134214 ESTε 37
428200 AI039624 Hs 98388 ESTs 37
452462 BE173515 gb RC2-HT0560-210200-012-f03 HT0560 Homo 37
418759 AA227879 Hs 187621 ESTs 37
450497 H64159 Hs 15328 ESTs 37
447785 AL041765 Hs 340375 ESTs 37
451746 M86178 Hε 311258 ESTs 37
416321 H94331 Hε 34024 ESTs 37
448135 AI470874 Hs 343799 ESTε 37
405510 ENSP00000233779* Hypothetical 680 kDa p 37
407437 AF220264 gb Homo εapienε MOST-1 mRNA, complete ed 37
451859 H44491 Hs 252938 ESTε, Weakly similar to ALULHUMAN ALU S 37
455135 AW857989 gb PM2-CT0328-281299-003-e04 CT0328 Homo 37
409189 AA125984 gb zn27h06 rl Stratagene neuroepithelium 37
420300 AA258245 Hs 127573 Homo sapienε FKSG41 (FKSG41) mRNA, compl 37
427726 AI359144 Hs 143688 Homo εapienε cDNA FLJ23031 fiε, clone L 37
434306 AW081757 Hs 44241 Homo εapieπε cDNA FU21447 fis, clone C 37
456354 X56411 Hs 1219 alcohol dehydrogenase 4 (clasε II), pi p 37
419261 X07876 Hs 89791 wmgleεε-type MMTV integration site fami 37
422899 D16471 Hs 121571 Human mRNA, Xq terminal portion 37
447458 AI741082 Hs 158961 ESTs 37
411421 BE272110 Hs 21177 ESTs 37
439075 AF085933 Hs 292620 ESTs 37
440947 AA910403 ESTs 37
417565 AI203405 Hs 47831 ESTs 36
430096 U91935 Hs 233321 Retina-deπved POU-domain fxtor-1 36
448658 H71739 Hs 200227 ESTs, Moderately similar to A53959 throm 36
404561 tnohorhmophalangeal syndrome I gene (T 36
429073 AA446167 Hs 47385 ESTs 36
419002 T78625 Hs 268594 ESTs 36
450630 AA010429 Hs 191939 ESTε 36
455067 AW854538 gb RC3-CT0255-200100-024-b02 CT0255 Homo 36
412768 AW996044 Hs 26239 Human DNA εequence from clone RP11-438B2 36 439481 AF086294 Hs 125844 ESTs 36
419622 AA452054 Hs 119338 ESTs 36
449821 AI671141 Hs 211122 ESTs 36
451193 N29850 Hs 44098 ESTs 36
412701 AW984757 gb RC1 HN0015 040400 011-g10 HN0015 Homo 36
419611 AB031479 Hs 91600 SEEK1 protein 36
433563 AI732637 Hs 277901 ESTs 36
427235 AH 26288 Hs 192232 ESTs 36
449045 BE072483 Hs 278337 Homo sapienε cDNA FLJ11537 fis clone HE 35
401132 C12000517* gι|4758712|ref|NP 004659 1| a 35
421105 AA766501 Hs 125113 ESTs 35
405264 NM.030813* Homo sapiens suppreεεor of po 35
417675 AI808607 Hs 3781 εimilar to munne leucine rich repeat pr 35
449988 AW372068 Hs 201420 ESTε Moderately similar to ALU7.HUMAN A 35
434763 AA648618 gb ns07a11 r1 NCI CGAP Ew1 Homo sapiens 35
416379 N38857 Hs 203933 ESTs 35
407557 Z83803 gb H sapienε mRNA for axonemal dynein he 35
437956 AA773283 Hs 203559 hypothetical protein FLJ 12701 35
403510 Target Exon 35
451722 H86374 Hs 40861 ESTε 35
435681 AA694192 Hs 148979 ESTε 35
427125 AA683362 Hs 97612 ESTε 35
424287 AL133105 Hε 144633 hypothetical protein DKFZp434F2322 34
434497 AI821803 Hε 136580 ESTε 34
453682 T79703 gb yd71e08 r1 Soares fetal liver spleen 34
404848 ENSP00000240769* BG15303 1 (similarto C 34
417435 NM 005181 Hs 82129 carbonic anhydrase III muscle spxific 34
442231 W02434 Hs 222413 ESTε 34
450297 AW901347 Hs 38592 hypothetical protein FLJ23342 34
436340 R42246 Hs 21606 ESTs 34
441596 AA939300 Hs 206768 ESTs 34
456995 T89832 Hs 170278 ESTs 34
456304 AI820973 gb nc21c02 y5 NCI CGAP Pr1 Homo sapiens 34
427033 AI457449 Hs 192817 ESTs 34
400379 NM 018432 Homo sapiens ovanan cancer related prot 34
410551 R36730 Hε 21816 ESTs 34
423357 AI285124 Hs 157505 ESTs 34
450582 AI339732 G-πch RNA sequence binding factor 1 34
437662 AA765387 Hs 145095 ESTs 34
442388 AW663442 Hs 129485 ESTs 34
445004 AI204616 Hs 148701 ESTs 34
450597 AI701635 Hs 207077 ESTs 34
438801 AA825971 Hs 124284 ESTs 34
445432 AV653771 gb AV653771 GLC Homo sapiens cDNA clone 34
450003 AA777809 Hs 191995 ESTs 34
431408 AA504757 Hs 105738 ESTs 34
428923 BE047698 Hs 188785 ESTs 34
407344 AI038025 Hs 271418 gb ox29f07 1 Soares total fetus Nb2HF8 33
425523 AB007948 Hs 158244 KIAA0479 protein 33
427473 AW274439 Hs 252709 ESTε 33
437115 AA744703 Hs 129030 ESTε 33
434520 AA205273 Hε 177011 hypothetical protein 33
447282 AI989963 Hs 197505 ESTε 33
453328 AW292635 Hs 346145 ESTε 33
418985 AI042330 Hs 87128 hypothetical protem FU23309 33
449256 AA059050 Hs 59847 ESTε 33
432550 AW297206 Hs 164018 ESTε 33
423101 M83941 Hs 123642 EphA3 33
424853 BE549737 Hs 132967 Human EST clone 122887 manner transposo 33
410700 AA352335 Hs 65641 hypothetical protein FLJ20073 33
418719 AW975590 Hs 161707 ESTs 33
402703 Target Exon 33
455710 BE072049 gb PM4-BT0532 170100-004-106 BT0532 Homo 33
452011 AW628911 Hs 211429 ESTs 33
453973 AI291895 Hs 61993 ESTs Weakly similar to ALU1 HUMAN ALU S 33
420355 AW968263 Hs 123126 ESTs 32
418898 T66847 Hs 194040 ESTs Weakly similar to I38022 hypotheti 32
418986 AI123555 Hs 81796 ESTs 32
449570 AA001793 gb zh86c06 r1 Soares_fetal_lιver_spteen_ 32
447516 W05355 Hs 102971 hypothetical protein FLJ14751 32
408304 AW810279 gb MR4-ST0125-151299-029 a09 ST0125 Homo 32
402454 C1002501* gι|129092|εp|P23270|OLF7 RAT O 32
411552 AW851255 gb IL3 CT0220 160200 066 H02 CT0220 Homo 32
407896 D76435 Hs 41154 Zic family member 1 (odd paired Droεophi 32
435786 H09175 Hε 26085 ESTε 32
447597 AI886036 Hε 213675 ESTε 32
432625 AI243596 Hε 94830 ESTε Moderately similar to T03094 A km 32
459535 AV654907 gb AV654907 GLC Homo sapiens cDNA clone 32
447183 AI554733 Hε 173182 ESTs 32
426629 AI203933 Hε 97142 ESTs 32
447892 AI435848 Hs 172978 ESTs 32
457136 AA428240 Hs 126083 ESTs 32
443585 AW466983 Hs 283949 eπamelin 3 1 451399 AL042110 Hs 326728 ESTs 31
450687 AA495800 gb zw05b07 si Soareε NhHMPu S1 Homo εapi 31
416812 H91010 Hs 44940 ESTε 3 1
452102 U04343 Hs 27954 CD86 antigen (CD28 antigen ligand 2, B7- 3 1
434512 AW139932 Hε 188941 ESTs , 3 1
458251 AL040927 Hs 210422 ESTs ^ 3 1
439950 AW937417 Hs 293561 ESTs 3 1
429569 AA454993 Hs 138343 ESTs, Weakly similar to I78885 seπne/th 3 1
403805 Target Exon 3 1
422666 AA677981 Hs 119023 SMC2 (structural maintenance of chromoso 3 1
408799 AA059412 Hs 47986 hypothetical protein MGC10940 31
429350 AI754634 Hs 131987 ESTs 31
430454 AW469011 Hs 105635 ESTs 31
441817 AW969706 Hs 293332 ESTs 3 1
427773 AA412290 Hs 98124 ESTs 31
415901 H08396 Hs 76118 ubiquitin carboxyl terminal esteraεe L1 3 1
445758 R60715 Hs 25804 ESTε 31
403291 Target Exon 31
436295 N73895 gb za62d06 ε1 Soareε fetal liver spleen 3 1
455772 W28799 gb 52g11 Human retina cDNA randomly prim 3 1
418037 AI990212 Hs 86447 ESTs 31
438142 T90309 Hs 269651 ESTs 3 1
416423 H54375 Hs 268921 ESTs 31
448765 R15337 Hs 21958 Homo sapienε mRNA, cDNA DKFZp547D086 (fr 31
457021 AW968934 Hs 173108 Homo εapiens cDNA FLJ21897 fis, clone H 31
420301 AA767526 Hs 22030 paired box gene 5 (B-cell lineage spxif 31
420721 AA927802 Hs 159471 ZAP3 protein 31
436013 AA703419 Hs 287749 Homo εapienε cDNA FLJ23593 fis, clone L 31
441492 AI149998 Hs 146346 ESTs 31
410869 AW808361 gb MR1-ST0111-111099 003404 ST0111 Homo 3 1
419386 AA236867 ESTε, Weakly similar to I38022 hypotheti 3 1
435628 W88732 Hs 36107 ESTs 30
444326 AI939357 Hs 270710 ESTs 30
413774 AA131782 Hs 182314 ESTs 30
434352 AF129505 Hs 86492 small muscle protein, X-lmked 30
434269 AK001991 Hs 3781 similar to munne leucine-πch repeat pr 30
416422 H60457 ESTs, Moderately similar to ZN91 HUMAN Z 30
416642 T96118 Hs 226313 ESTs 30
439182 AF086030 Hs 21621 hypothetical protein DKFZp762O076 30
418948 AI217097 gb qd43h07 x1 Soares fetal heart_NbHH19W 30
433796 AA810867 Hs 186997 ESTs 30
427813 D29833 Hs 2207 salivary proline πch protein 30
405733 NM 021140* Homo sapiens ubiquitously fra 30
426743 AA383833 Hs 245022 ESTs 30
449913 AA004696 Hs 333016 ESTs 30
454096 AW062757 gb CMO-CT0103-120899-037-g07 CT0103 Homo 30
440129 AA865818 Hs 174936 ESTs, Weakly similar to S71886 Ste20 lik 30
410929 H47233 Hε 30643 ESTs 30
458187 D56919 Hε 265848 myomegalm 30
429430 AI381837 Hs 155335 ESTs 30
451391 AA017410 Hs 40568 ESTs 30
414951 AW794931 Hs 100861 hypothetical protein FU 14600 30
TABLE 65B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank ∞cesεion numbers
Pkey CAT Number Accession 408304 1050848.1 AW810279 BE146684 BE146693 BE146694 BE146679AW810472AW810208AW810356 AW810193 AW178838 AW178837AW178857 AW810515
AW810330 AW810514AW810441 AW810358 AW178852AW810359 AW810322AW810327 AW810211 AW178835AW810635 AW810288
AW810263 AW810325 AW810443 AW8
409189 110687 1 AA125984 AA127189 AA065075 AA070377 AA100017 AA079891 AA113255 AA075168 AA082764 AA083380 N84829 AA084752 AA076512
AA085119 AA085208 AA085045
410559 1208283 1 AW754192 W00554 AW857797 AW754203 AW754197 AW754193
410790 1221131 1 AW803357 AW803423 AW812233 R06814
410869 1225123.1 AW808361 AW808404 AW808386 AW808594 AW808654 AW808813 AW808551 AW808676 AW808350 AW808406 AW808694 AW808934
AW808829 AW808385 AW808422 AW808401 AW808409 AW808760 AW808863 AW808521 AW808539 AW808609 AW808472 AW808739
AW808704 AW808558 AW808714 AW808420 AW8
411436 1245660 1 AW846433 AW846159 AW846377 AW846528
411518 1248692 1 AW850246 AW850251 AW850302
411552 1249255 1 AW851255 AW851432 AW850955
412701 1322288 1 AW984757 AW984797 AW984734 AW984745
412988 1342150 1 BE046680 BE046738 BE044958
413081 1348563 1 BE064415 BE064430 BE064448
413525 1374635 1 BE145899 BE145848 BE145849 BE145853 BE145927 BE145925
416009 1566379 1 Z43062 R13213 H14422
416422 1593811 1 H60457 H68709 H73528 H54335 R87154
418059 171879 T AA211586 F35799 AA211641 F29720 AW937387 AW937408
418387 174731 1 R18085 AA219028 R17712 Z44345
418948 180808 1 AI217097 AW886090 W38035 W38792 AA232835 AW936043 419386 1843561 AA236867 AA237066 AA354236 AW957759 H08961
420352 1929791 BE258835 AW968316 AA258918 AW843305 R14744 AI580388 BE071923 R36280
421926 2092461 AA300591 AW963893AA300493
424200 2365951 AA337221 AA336756AW966196
424686 2424861 AA345504 AA345251 AW963243
424994 2457861 AW954525 AI372685 AA349501 AI372687 H10564
428002 2856021 AA418703AA418711 BE071915 BE071920 BE071912
430535 3196431 AW968485 AW968670 AA480922 BE350425
432765 3539071 AJ003429 AJ003367 AA564825
433523 3688731 H29882 AW665533 AW149901 AI572917 AA598500 AI686466 AI336390 AW864390 AW864320
434381 3851551 AA631834 AA633425 AA632455 AI792312 AI792311
434589 38929 T AF147363T47219 T47218
434763 3928471 AA648618AW974389 H51771
436295 417331 N73895AJ001872
440947 5059041 AA910403 AI815593 W58361 AW162520 AI816550
442481 5435881 N99828 BE079873 AI110738 AF074645
445432 639431 AV653771 BE089370
449570 810181 AA001793 AA001871
450317 8319561 AI692689 R14223 R18395
450582 839331 AI339732 AA010300 AW515041 AA768334 N29860 AA425874 AA425118 AA865829 AW936878
450687 843271 AA495800 AA495737 AA010736 AA654716 AA640726
452462 9185801 BE173515 BE173560 AI902860
453682 9774541 T79703T96307AL079725
454096 10074491 AW062757 AW176890 AW062758 AW176895 AW176869 AW176900 AW176897 AW176928 AW176868 AW176892
454171 10492401 AW854832 AW854798 AW854857 AW854816 AW854834 AW854817
454457 12072741 AW753456 AW753036 AW854868 AW854862
454585 12258521 BE069128 BE069023 AW809375
454665 12285991 AW812866 AW812746 AW812747 AW812884 AW812763 AW812722
454860 12377321 AW835767 AW835537 BE160187
454968 12470291 AW849046 AW847956 AW849039 AW847957 AW848279 AW848698 AW849034 AW849033
455067 12520501 AW854538 AW854418 AW854412
455135 12547291 AW857989 AW858016 AW861677 AW861689 AW861691 AW858056
455276 1272541 1 BE176479 BE176678 BE176357 BE176550 AW886079 BE176676 BE176615 BE176555 BE176489 BE176610 BE176362
455388 12879041 AW936234AW936074AW936181 AW936179AW936217AW936077AW936227AW936191
455490 12978261 AW953477 Z41970 F12435T73989T09387
455646 13485571 BE064420 BE064435 BE064429 BE064414 BE064400 BE064517
455710 13523681 BE072049 BE069471 BE069489 BE069478 BE069479 BE069492 BE069485 BE072122 BE072124 BE069491 BE069486 BE069464
455747 13558771 BE074910 BE074913 BE074911 BE074903 BE074892 BE074935
455772 13631141 W28799 BE086078
455801 13705081 BE140643 BE140645 BE140644 BE140657 BE140660 BE140659 BE140661
456304 1768201 AI820973 AI734077 AI820984 AA225796 AA225060 AA225101
457374 3287581 AA493662 AW897396 BE154814
TABLE 65C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromoεome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exons were predicted
Nt position Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 400533 6981826 Minus 277132-277595
400746 7329328 Minus 147703-147896
401132 8705350 Minus 85679-85795
401459 9212270 Minus 182001-183323
402145 8018280 Plus 113086-114800 402454 7534025 Minus 14826-15803
402703 8705069 Minus 15335-15500
403242 7637817 Minus 11297-12511
403291 7230870 Plus 95177-95435
403305 8099945 Plus 114632-114805 403333 8568833 Minus 124794-124941
403371 9087278 Plus 105655-106050
403433 9719611 Minus 72225-72437
403481 9965004 Pluε 93496-93633
403510 7652047 Plus 61866-62027 403667 6850483 Minus 1344-1442,1545-1697
403805 8140491 Minus 51483-51742,53429-53511
404003 8655948 Plus 198349-199096
404561 9795980 Minus 69039-70100
404592 9943965 Minus 39067-39225 404848 8248647 Minus 23955-24034,2514325264
404967 7523744 Minus 89944-90729
404995 6006247 Minus 154015-154123
405264 7329374 Plus 28556-28684
405321 3419846 Minus 44654-45210 405348 2914717 Minus 43310-43462
405510 7630909 Minus 101028 101174
405549 1552494 Plus 10878 11048
405733 9884689 Plus 124832-125051 Table 66A lists about 370 genes up regulated in BPH compared to prostate cancer and normal adult tissues These were εelected from 59680 probeεetε on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" BPH to "average" prostate cancer and normal adult tissueε waε greater than or equal to 30 The "average" BPH level waε εet to the 75* percentile amongst BPH tissues The "average" prostate cancer and normal adult tisεue level waε set to the 85* percentile amongst malignant prostate tissues and normal adult tisεueε In order to remove gene-εpecific background levelε of non εpecific hybridization, the 10* percentile value amoπgεt non malignant body tiεεueε waε subtracted from both the numerator and the denominator before the ratio was evaluated
TABLE 66A ABOUT 370 GENES UP-REGULATED IN BENIGN PROSTATIC HYPERPLASIA COMPARED TO PROSTATE CANCER AND NORMAL ADULT TISSUES
" key unique tos proDeset lαentmer numDer
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title _R1 Ratio of BPH tissue to prostate tumor and normal body tissue
Pkey ExAccn Unigene ID Unigene Title R1
410929 H47233 Hs 30643 ESTs 21 1
450693 AW450461 Hs 203965 ESTs 167
418432 M14156 Hs 85112 insulin-like growth factor 1 (εomatomedi 14 2
432473 AI202703 Hs 152414 ESTs 11 3
446336 AW815036 Hs 151251 ESTs 109
407275 AI364186 gb qw34h07 x1 NCI CGAP_Ut4 Homo sapiens 107
428134 AA421773 Hε 161008 ESTs 10 2
400297 AI127076 Hs 306201 hypothetical protein DKFZp56401278 98
433466 AA508353 Hs 105314 relaxm 1 (H1) 95
415293 R49462 Hs 106541 ESTs 91
458072 AI890347 Hs 271923 Homo sapiens cDNA FU22785 fis, clone K 88
428927 AA441837 Hs 90250 ESTε 86
420345 AW295230 Hs 25231 ESTε 85
453387 AI990741 Hs 252809 ESTs 82
454457 AW753456 gb QV2-CT0261-261099 011-d11 CT0261 Homo 77
441247 AW118681 Hs 128051 Homo sapiens thymic stromal lymphopoiefi 75
431576 M76665 Hs 275215 hydroxysteroid (11 beta) dehydrogenaεe 1 74
400080 Eoε Control 74
431448 AL137517 Hs 306201 hypothetical protein DKFZp56401278 74
404592 NM 022739* Homo εapienε E3 ubiquitin fig 73
420352 BE258835 gb 601117374F1 NIH MGC 16 Homo sapiens c 73
438231 AW594539 Hs 155689 ESTs 73
410330 AW023630 Hs 159425 ESTs 72
449300 AI656959 Hs 346514 ESTε 7 1
449249 T52285 Hs 193115 Homo sapiens mRNA for KIAA1764 protein, 70
426384 AI472078 Hs 303662 hypothetical protein FU13189 (FU13189) 68
454171 AW854832 gb QV2-CT0261-201099 011405 CT0261 Homo 66
408197 AA282262 Hs 107410 ESTs, Weakly similar to A46010 X linked 66
429732 U20158 Hs 2488 lymphxyte cytosolic protein 2 (SH2 doma 66
421154 AA284333 Hs 287631 Homo sapiens cDNA FLJ14269 fis, clone PL 65
431467 N71831 Hs 256398 Homo sapienε mRNA, cDNA DKFZp434E0528 (f 65
424433 H04607 Hs 9218 ESTε 65
442481 N99828 gb za32c04 r1 Soareε fetal liver εpleen i 64
425312 AA354940 Hs 145958 ESTs 64
426140 AF131798 Hs 343768 Homo sapienε clone 25119 mRNA sequence 64
440911 AA909536 Hs 143562 ESTs 64
400533 ENSP00000209376* PRED65 protein (Fragmeπ 62
418310 AA814100 Hs 86693 ESTs 62
403667 Target Exon 61
436396 AI683487 Hs 152213 wmglesε type MMTV integration εite fami 61
404003 Target Exon 59
424853 BE549737 Hs 132967 Human EST clone 122887 manner fraπsposo 59
438138 R98299 Hs 177502 ESTs 59
424940 AA985308 Hs 283902 ESTs 58
434485 AI623511 Hs 118567 ESTs 58
453200 AA033832 Hs 212433 ESTs 57
428002 AA418703 gb zv98c03 s1 Soares.NhHMPu.S1 Homo sapi 57
424850 AA151057 Hs 153498 chromosome 18 open reading frame 1 56
445444 AA380876 Hs 270 plxkstππ homology, Sx7 and coiled/coi 56
443361 AI792628 Hε 133273 ESTs 56
421513 X00949 Hε 105314 relaxm 1 (H1) 55
439079 AF085937 Hs 38348 ESTs 55
430535 AW968485 gb EST380561 MAGE resequences, MAGJ Homo 55
436578 AI091435 Hs 134859 ESTs 55
424051 AL110203 Hs 138411 Homo sapiens mRNA, cDNA DKFZp586J1922 (f 54
421863 AI952677 Hs 108972 Homo sapienε mRNA, cDNA DKFZp434P228 (fr 54
435072 AW592176 Hs 116932 ESTs 54
435375 AI733610 Hs 187832 ESTs 54
444609 AW571659 Hs 278081 ESTs 54
416602 NM 006159 Hs 79389 πel (chicken) like 2 54
433087 AI720686 Hs 152520 ESTs 53
439092 AA830149 gb oc44f08 s1 NCI CGAP GCB1 Homo sapiens 53
437267 AW511443 Hs 258110 ESTs 53
441916 AA993571 Hs 129075 ESTs 53
452784 BE463857 Hs 151258 hypothetical protein FU21062 53
452531 AA429462 Hs 293946 ESTs, Weakly similar to 138022 hypotheti 53 423101 M83941 Hs 123642 EphA3 53
437587 AI591222 Hs 72325 Human DNA εequeπce from clone RP1-187J11 52
415890 H08225 Hs 268712 ESTs 52
454968 AW849046 gb IL3-CT0214-150300-085-H06 CT0214 Homo 52
408385 AF055634 Hs 44553 uπc5 (C elegans homolog) c 52
437752 AA767376 Hε 291631 ESTs, Moderately similar to S65657 alpha 52
446495 D60923 Hε 153460 ESTs 52
422906 U80773 Hε 121580 Human EST clone 42944 manner transposon 52
427726 AI359144 Hε 143688 Homo sapiens cDNA FLJ23031 fis, clone L 52
426748 AL048409 Hs 97177 ESTs, Weakly similar to ALU1 HUMAN ALU S 52
436338 W92147 Hs 118394 ESTs 52
416706 AA314676 Hε 288945 hypothetical protein FLJ13448 5 1
440129 AA865818 Hε 174936 ESTs, Weakly similarto S71886 Ste20-lιk 51
445238 AA883971 Hε 187506 ESTs 5 1
450582 AI339732 G-πch RNA sequence binding factor 1 5 1
420533 AI809510 Hs 118971 ESTε 5 1
438447 AI082883 Hs 30732 hypothetical protein FU13409, KIAA1711 51
440354 AA889386 Hs 125468 ESTε 50
452891 N75582 Hs 212875 ESTε, Weakly similar to DYH9_HUMAN CILIA 50
457374 AA493662 gb nh05d12 s1 NCI_CGAP_Thy1 Homo εapienε 50
408829 NM 006042 Hs 48384 heparan sulfate (glucosamine) 3-O-εulfot 50
448041 AW292769 Hs 206228 ESTε 50
457653 AI820719 Hs 154662 DnaJ (Hεp40) homolog, εubfamily A, membe 49
450497 H64159 Hs 15328 ESTs 48
438132 AA907076 Hs 122060 ESTs 48
414818 BE541217 Hs 23606 ESTs 48
429433 AA452899 Hs 213586 ESTs, Weakly similar to KIAA1353 protein 48
433523 H29882 ESTs 48
450317 AI692689 gb wd86g05 x1 NCI CGAP Lu24 Homo sapienε 48
443635 AI080230 Hs 134214 ESTε 48
430172 AA468591 Hs 161889 ESTε 48
452843 AI796769 Hs 208320 ESTε 47
427302 AA400540 Hs 135282 Homo sapiens cDNA FLJ11554 fis, clone HE 47
452031 AA741314 Hs 865 RAP1A, member of RAS oncogene family 47
423789 AK002084 Hε 132851 hypothetical protein FLJ 11222 47
417173 U61397 Hε 81424 ubiquitin-like 1 (sentππ) 46
420931 AF044197 Hs 100431 small inducible cytokine B subfamily (Cy 46
454024 AA993527 Hs 293907 hypothetical protein FLJ23403 46
405348 C7001664 gι|12698061|dbj|BAB21849 1| (AB 46
419511 AA429750 Hs 75113 general transcription factor IIIA 46
447058 AI939456 Hs 160870 ESTs 46
428218 AA424266 Hs 123642 EphA3 46
430697 AA484207 Hs 211867 ESTε 45
433280 AA581404 Hs 289037 Homo sapiens cDNA FLJ14135 fis, clone MA 45
449821 AI671141 Hs 211122 ESTs 45
420905 AA521307 Hs 186651 ESTs 45
439752 T78968 Hs 14411 ESTs 45
452055 AI377431 Hs 141693 hypothetical protein MGC10858 45
430188 AL049242 Hs 234794 Homo sapiens mRNA, cDNA DKFZp564B083 (fr 44
423352 AA324808 Hs 193576 ESTs 44
438042 AW296971 Hs 180610 ESTs 44
452978 AA029994 Hs 61523 ESTs 44
420154 AI093155 Hs 95420 JM27 protein 44
428249 AA130914 Hs 183291 zinc finger protein 268 44
442242 AV647908 Hs 90424 Homo εapienε cDNA FLJ23285 fiε, clone H 44
452498 AK000101 Hs 29700 hypothetical protein FLJ20094 44
459527 AW977556 Hs 291735 ESTε, Weakly similar to I78885 seπne/th 43
433597 AA708205 Hs 100343 ESTs 43
416312 W02640 Hs 16247 ESTs, Weakly similar to 2004399Achromos 43
420111 AA255652 gb zε21h11 d NCI CGAP GCB1 Homo sapiens 43
459045 N69101 Hs 40730 ESTs 43
409705 M37762 Hs 56023 brain-derived neurotrophic factor 43
433433 AI692623 Hs 121513 Homo sapienε clone Z'3-1 placenta expres 42
427908 AA417272 Hs 24122 ESTs 42
432765 AJ003429 gb AJ003429 Selxted chromosome 21 cDNA 42
413525 BE145899 gb MR0-HT0208-221299-204-M0 HT0208 Homo 42
420355 AW968263 Hs 123126 ESTs 42
427521 AW973352 Hs 290585 ESTs 42
458912 AI911066 ESTs 42
410790 AW803357 gb IL2-UM0079-090300-050-A08 UM0079 Homo 41
415245 N59650 Hs 27252 ESTs 41
434360 AW015415 Hs 127780 ESTs 41
442786 H50733 Hs 256261 ESTs, Moderately similar to ALU8.HUMAN A 41
450597 AI701635 Hs 207077 ESTs 41
424200 AA337221 gb EST41944 Endometπal tumor Homo sapie 41
445206 AI350199 Hs 269990 ESTs 41
438431 AW207860 Hs 293116 ESTs 4 1
448152 AI741053 Hs 170770 ESTs 41
438875 AA827640 Hε 189059 ESTs 41
400746 Target Exon 41
413081 BE064415 gb RC4-BT0311-241199-012-b03 BT0311 Homo 41
404967 Target Exon 40
427203 AW629517 Hε 244855 ESTs 40 442338 AI761976 Hs 156080 ESTs 40
455276 BE176479 gb RC3 HT0585 160300 022-b09 HT0585 Homo 40
452903 AI953425 Hs 345291 ESTs, Weakly similar to I38022 hypotheti 40
435136 R27299 Hs 10172 ESTs 40
416760 H85182 Hs 191327 ESTs, Highly similar to KIAA1102 protein 40
421312 AA824627 Hs 291670 ESTs 40
441568 AI733322 Hs 127176 ESTs 40
441736 AW292779 Hs 8182 ESTs 40
448882 AJ001531 Hs 22404 protease, serine, 12 (neurotrypsiπ, moto 40
434222 AF119886 Hs 283941 Homo sapiens PR02591 mRNA, complete eds 39
420301 AA767526 Hs 22030 paired box gene 5 (B-cell lineage specif 39
429066 AA868555 Hs 178222 ESTs 39
435878 R08330 Hs 20152 ESTs 39
447530 AW192063 Hs 248865 ESTs, Moderately similar to JC5238 galac 39
412988 BE046680 gb hn42h03 x1 NCI.CGAP.RDF2 Homo sapiens 39
410196 AI936442 Hs 59838 hypothetical protein FLJ 10808 39
411084 T18987 Hs 125472 ESTs, Moderately similar to KIAA0877 pro 39
419629 AB020695 Hs 91662 KIAA0888 protein 39
455646 BE064420 gb RC4-BT0311-241199012-cOδ BT0311 Homo 39
414441 AA234759 Hs 132950 ESTs 39
425810 AI923627 Hs 31903 ESTε 39
409111 AL043362 Hs 7984 pleckstπn homology, Sec7 and coiled/coi 39
411479 AW848047 gb IL3-CT0214-291299 052-A12 CT0214 Homo 39
440450 AI333129 Hs 156147 ESTs 38
428342 AI739168 Homo sapiens cDNA FLJ13458 fis, clone PL 38
431421 AW969118 Hs 108144 ESTs Weakly similar to unnamed protein 38
416009 Z43062 gb HSG12E041 normalized infant brain cDN 38
416534 H69043 Hs 224961 Homo εapienε cDNA FLJ14366 fiε, clone HE 38
407198 H91679 gb yv04a07 s1 Soares fetal liver spleen 38
419831 AW448930 Hs 5415 ESTs 38
424830 AW270580 Hs 189311 ESTs, Weakly similar to putative p150 [H 38
431447 AA505138 Hs 291341 ESTs 38
435932 W03928 Hs 114524 ESTs 38
442447 AA999723 Hs 129607 ESTs 38
403242 Target Exon 38
433908 AW298141 Hs 157975 ESTs 38
454037 AW998716 gb PM4-BN0067-250300 002411 BN0067 Homo 37
432101 AI918950 Hs 123642 EphA3 37
418759 AA227879 Hs 187621 ESTs 37
452462 BE173515 gb RC2-HT0560-210200 012403 HT0560 Homo 37
448568 AA149121 Hs 71947 ESTε 37
447785 AL041765 Hs 340375 ESTε 37
451746 M86178 Hs 311258 ESTs 37
436345 AA873008 Hs 121572 ESTs 37
446862 AV660697 Hs 282700 ESTs 37
419875 AA853410 Hs 93557 proenkephalin 37
421040 AA715026 Hs 135280 ESTs 37
454860 AW835767 gb QV4-LTOO16-24O200-11O-bO8 LT0016 Homo 37
450687 AA495800 gb zw05b07 s1 Soareε.NhHMPu.SI Homo εapi 37
407437 AF220264 gb Homo εapiens MOST-1 mRNA, complete cd 37
431474 AL133990 Hs 190642 CEGP1 protein 37
448004 AW451477 Hs 257456 ESTε 37
419261 X07876 Hs 89791 wmgleεε-type MMTV integration site fami 37
422899 D16471 Hs 121571 Human mRNA, Xq terminal portion 37
439075 AF085933 Hs 292620 ESTs 37
440947 AA910403 ESTε 37
447458 AI741082 Hε 158961 ESTs 37
403481 Target Exon 36
404561 tπchorh ophalangeal syndrome I gene (T 36
417565 AI203405 Hε 47831 ESTs 36
430096 U91935 Hε 233321 Retina-derived POU domain fxtor-1 36
448658 H71739 Hs 200227 ESTs, Moderately similar to A53959 throm 36
449655 AI021987 Hs 59970 ESTs 36
450630 AA010429 Hs 191939 ESTs 36
455067 AW854538 gb RC3-CT0255-200100-024-b02 CT0255 Homo 36
423566 AW976434 Hε 3623 hypothetical protein FLJ 11220 36
451193 N29850 Hε 44098 ESTs 36
420026 AI831190 Hs 166676 ESTs 36
426917 AA913814 Hs 172854 DKFZP586B0923 protein 36
429430 AI381837 Hs 155335 ESTε 36
433563 AI732637 Hs 277901 ESTε 36
443744 AI084326 Hs 271548 ESTs, Weakly similar to 178885 εeππe/th 35
456373 BE247706 Hs 89751 membrane spanning 4-domaιns, subfamily A 35
419589 AW973708 Hs 201925 Homo sapiens cDNA FLJ13446 fis, clone PL 35
401132 C12000517* gι|4758712|ref|NP_004659 1| a 35
421105 AA766501 Hs 125113 ESTs 35
435177 AI018174 Hs 42936 ESTs 35
434763 AA648618 gb ns07a11 r1 NCI_CGAP_Ew1 Homo sapiens 35
449988 AW372068 Hs 201420 ESTs, Moderately similar to ALU7.HUMAN A 35
450216 AA873345 Hs 60226 Homo εapiens, clone IMAGE 3621638, mRNA, 35
403510 Target Exon 35
435681 AA694192 Hs 148979 ESTs 35
451722 H86374 Hs 40861 ESTs 35 430865 AI073424 Hs 5232 HSPC125 protein 35
444800 AW119071 Hε 153287 ESTs 35
428647 AA830050 Hε 124344 ESTs 35
412775 AA709046 Hs 27552 Homo sapiens mRNA cDNA DKFZp586N2424 (f 35
429643 AA455889 Hs 167279 FYVE-fiπger-containiπg Rab5 effector pro 35
443324 R44013 Hs 164225 ESTs 35
430124 AW204994 Hs 253450 ESTs 34
430701 AI760833 Hs 293971 ESTs 34
436714 AA728964 Hs 293399 ESTs 34
404848 ENSP00000240769* BG15303 1 (similar to C 34
408480 AI350337 Hs 164568 fibroblast growth factor 7 (keratmocyte 34
412494 AL133900 Hs 792 ADP-nbosylatioπ factor domain protein 1 34
417435 NM.005181 Hs 82129 carbonic anhydrase III, muscle specific 34
430403 AF039390 Hs 241382 tumor necrosis factor (ligand) superfami 34
436340 R42246 Hs 21606 ESTs 34
441596 AA939300 Hs 206768 ESTs 34
442231 W02434 Hs 222413 ESTs 34
447124 AW976438 Hs 17428 RBPMike protein 34
450297 AW901347 Hs 38592 hypothetical protein FU23342 34
453682 T79703 gb yd71 e08 r1 Soares fetal liver spleen 34
456995 T89832 Hs 170278 ESTs 34
405510 ENSP00000233779* Hypothetical 680 kDa p 34
400379 NM.018432 Homo sapienε ovarian cancer related prot 34
419964 AA811657 Hε 220913 ESTs 34
427033 AI457449 Hε 192817 ESTs 34
422321 AA906427 Hs 181035 hypothetical protein MGC11296 34
430829 AW451999 Hs 194024 ESTs ' 34
420721 AA927802 Hs 159471 ZAP3 protem 34
433628 AI821784 Hs 188578 ESTs 34
436703 AW880614 Hs 146381 RNA binding motif protein, X chromosome 34
429716 R25685 Hs 211933 collagen, type XIII, alpha 1 34
427235 AI126288 Hs 192232 ESTs 34
459646 AW883968 Hs 321190 gb QV3 OT0063-290300 135-c04 OT0063 Homo 34
428923 BE047698 Hs 188785 ESTs 34
431408 AA504757 Hs 105738 ESTs 34
438801 AA825971 Hs 124284 ESTs 34
445432 AV653771 gb AV653771 GLC Homo sapienε cDNA clone 34
450003 AA777809 Hs 191995 ESTε 34
448108 AW300021 Hs 170685 ESTs 33
425523 AB007948 Hs 158244 KIAA0479 protein 33
427473 AW274439 Hs 252709 ESTs 33
434520 AA205273 Hs 177011 hypothetical protein 33
447282 AI989963 Hs 197505 ESTs 33
447182 BE241868 Hε 17585 KIAA0801 gene product 33
432229 AW290976 Hs 143587 ESTs 33
418985 AI042330 Hs 87128 hypothetical protein FLJ23309 33
418719 AW975590 Hs 161707 ESTs 33
455710 BE072049 gb PM4-BT0532-170100 004406 BT0532 Homo 33
420300 AA258245 Hs 127573 Homo sapiens FKSG41 (FKSG41) mRNA, compl 33
416662 T25853 Hs 7538 ESTs 33
411436 AW846433 gb QV0-CT0179 070300-143-b02 CT0179 Homo 33
420851 AA281062 Hs 29493 hypothetical protein FU20142 33
428715 AW293716 Hs 53126 ESTε 33
429318 AW861930 Hs 102500 hypothetical protein dJ511E162 33
444246 H93281 Hs 10710 hypothetical protein FLJ20417 33
453973 AI291895 Hs 61993 ESTs, Weakly similar to ALU1 HUMAN ALU S 33
434497 AI821803 Hs 136580 ESTs 32
439306 BE220199 WD40 protein Cιao1 32
420608 BE548277 Hs 103104 ESTs 32
418986 AI123555 Hs 81796 ESTs 32
438118 AW753311 Hs 346690 ESTε 32
447516 W05355 Hs 102971 hypothetical protein FLJ14751 32
449570 AA001793 gb zh86c06 r1 Soares_fetal_lιver_εpleen_ 32
424994 AW954525 gb EST366595 MAGE resequences, MAGC Homo 32
417675 AI808607 Hs 3781 similar to murine leucine-πch repeat pr 32
402145 Target Exon 32
448131 AI675054 Hs 200481 ESTs 32
422352 AA766296 Hs 99200 ESTs 32
432625 AI243596 Hs 94830 ESTs, Moderately similar to T03094 A km 32
447183 AI554733 Hs 173182 ESTs 32
447597 AI886036 Hs 213675 ESTs 32
459535 AV654907 gb AV654907 GLC Homo sapienε cDNA clone 32
415467 R60891 Hs 260274 ESTε 32
434408 AI031771 Hs 132586 ESTε 32
456354 X56411 Hs 1219 alcohol dehydrogenaεe 4 (class II), pi p 32
453789 AA628517 Hs 118502 ESTs 32
412666 AL080116 Hs 74420 oπgm recognition complex, subunit 3 (y 32
418319 AW611703 Hs 190173 ESTs, Weakly similar to A46010 X-liπked 32
419088 AI538323 Hs 52620 integπn, beta 8 32
420397 NM.007018 Hs 97437 centrosomal protein 1 32
422165 AL041199 Hs 1481 histidine dxarboxylase 32
448044 A1458682 gb tk13e01 x1 NCI CGAP Lu24 Homo sapiens 32
454665 AW812866 gb RC3 ST0186-300100 θ"Ϊ7-b03 ST0186 Homo 3 1 405321 Target Exon 3 1
429569 AA454993 Hs 138343 ESTs, Weakly εimilar to I78885 εeπne/th 31
434512 AW139932 Hs 188941 ESTε 3 1
452102 U04343 Hs 27954 CD86 antigen (CD28 antigen ligand 2, B7- 31
433444 AW975324 Hs 129816 ESTs 31
410821 AH 14811 Hs 92526 ESTs, Weakly similar to T00365 hypotheti 3 1
415861 Z43123 Hs 144513 ESTs 3 1
422299 AK000181 Hs 114556 hypothetical protein FLJ20174 31
432527 AW975028 Hs 102754 ESTs 3 1
427773 AA412290 Hs 98124 ESTs 3 1
441817 AW969706 Hs 293332 ESTs 31
416812 H91010 Hs 44940 ESTε 3 1
417958 AA767382 Hs 193417 ESTε 3 1
407426 AF129533 gb Homo sapiens F-box protein Fbl3b (FBL 31
416423 H54375 Hs 268921 ESTs 3 1
418037 AI990212 Hs 86447 ESTs 3 1
419197 N48921 Hs 27441 KIAA1615 protein 31
420179 N74530 Hs 21168 ESTs 3 1
436295 N73895 gb za62d06 s1 Soares fetal liver spleen 3 1
405548 Target Exon 31
423595 R82826 Hs 220702 ESTε 3 1
412533 AA679863 Hs 69606 ESTε 3 1
434072 H70854 Hs 283059 Homo εapienε PRO1082 mRNA, complete cdε 3 1
405264 NM.030813* Homo εapienε εuppreεεor of po 3 1
410869 AW808361 gb MR1-ST0111-111099 003404 ST0111 Homo 31
425354 U62027 Hs 155935 complement component 3a rxeptor 1 31
441492 AI149998 Hs 146346 ESTε 3 1
447078 AW885727 Hs 9914 ESTs 31
435021 AA922192 Hs 54709 ESTs 30
408832 AW085690 Hs 63428 ESTs, Weakly similar to Z195.HUMAN ZINC 30
450580 N40087 ESTs 30
432319 AW510770 Hs 128386 ESTs 30
453713 R20640 Hs 79133 cadhenn 8, type 2 30
445784 AI253155 Hs 146065 ESTε 30
416642 T96118 Hs 226313 ESTε 30
418948 AI217097 gb qd43h07 x1 Soares fetaLheart NbHH19W 30
433796 AA810867 Hs 186997 ESTs 30
439182 AF086030 Hs 21621 hypothetical protein DKFZp762O076 30
404995 ENSP00000251890' Monocytic leukemia zinc 30
444794 AI419991 Hs 145225 ESTs 30
443634 H73972 Hs 134460 ESTs 30
420133 AA426117 Hs 155543 ESTs 30
407829 AA045084 Hs 29725 hypothetical protein FLJ13197 30
426743 AA383833 Hs 245022 ESTs 30
442326 H92962 Hs 124813 hypothetical protein MGC14817 30
449913 AA004696 Hs 333016 ESTs 30
454096 AW062757 gb CMO-CT0103-120899 037-g07 CT0103 Homo 30
419622 AA452054 Hs 119338 ESTs 30
449745 AI668593 gb yl38a05 x5 Soares breast 3NbHBst Homo 30
428412 AA428240 Hs 126083 ESTε 30
428200 AI039624 Hs 98388 ESTε 30
414951 AW794931 Hs 100861 hypothetical protein FU 14600 30
431869 AA521136 Hs 190176 ESTε 30
451391 AA017410 Hs 40568 ESTε 30
452959 AI933416 Hs 189674 ESTε 30
TABLE 66B Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accesεion Genbank accession numbers
Pkey CAT Number Accession
410790 1221131 1 AW803357 AW803423AW812233 R06814
410869 1225123.1 AW808361 AW808404 AW808386 AW808594 AW808654 AW808813 AW808551 AW808676 AW808350 AW808406 AW808694 AW808934
AW808829 AW808385 AW808422 AW808401 AW808409 AW808760 AW808863 AW808521 AW808539 AW808609 AW808472 AW808739
AW808704 AW808558 AW808714 AW808420 AW8
411436 1245660 1 AW846433 AW846159 AW846377 AW846528
411479 1247077.1 AW848047 AW848202 AW848631 AW848142 AW848702 AW848121 AW848632 AW848140 AW848571 AW848009 AW848067 AW848069
AW848905 AW848214
412988 1342150 1 BE046680 BE046738 BE044958
413081 1348563 1 BE064415 BE064430 BE064448
413525 1374635 1 BE145899 BE145848 BE145849 BE145853 BE145927 BE145925
416009 1566379 1 Z43062 R13213 H14422
418948 180808 1 AI217097 AW886090 W38035 W38792 AA232835 AW936043
420111 190755 1 AA255652 AA280911 AW967920 AA262684
420352 192979 1 BE258835 AW968316 AA258918 AW843305 R14744 AI580388 BE071923 R36280
424200 236595 1 AA337221 AA336756 AW966196
424994 245786 1 AW954525 AI372685 AA349501 AI372687 H10564
428002 285602 1 AA418703 AA418711 BE071915 BE071920 BE071912 428342 290035.2 AI739168 AA426249 AI199636 AW505198 AW977291 AA824583 AA883419 AA724079 AI015524 AI377728 AW293682 AI928140 AA731438
AI092404 AI085630 AA731340
430535 3196431 AW968485 AW968670 AA480922 BE350425
432765 3539071 AJ003429 AJ003367 AA564825
433523 3688731 H29882 AW665533 AW149901 AI572917 AA598500 AI686466 AI336390 AW864390 AW864320
434763 3928471 AA648618 AW974389 H51771
436295 417331 N73895 AJ001872
439092 4685541 AA830149 AW978407 M85983 AW503637
439306 470881 BE220199 W01813 AF086118 N70760 BE221405
440947 5059041 AA910403 AI815593 W58361 AW162520 AI816550
442481 5435881 N99828 BE079873 AH 10738 AF074645
445432 63943 T AV653771 BE089370
448044 7471961 AI458682 H24240 R14537 R18426 AW867082
449570 810181 AA001793 AA001871
449745 8145341 AI668593 AI820774 R86205 H39971 H22177 H26241
450317 8319561 AI692689 R14223 R18395
450580 83929.1 N40087 H12925 AA460779 AA096372 BE160847 AW816890 AW816893 AW816577 AW816891 AW816882 AW816868 AW816889 AW816940
AW816892 AW816941 AW816578 AA029183 T83320 H86850 AA010295 BE160823 Z25353 AA150883 AW887764 AW023806 AW022095
AA164518 AA730973 W00417 W65303
450582 839331 AI339732 AA010300 AW515041 AA768334 N29860 AA425874 AA425118 AA865829 AW936878
450687 843271 AA495800 AA495737 AA010736 AA654716 AA640726
452462 9185801 BE173515 BE173560 A1902860
453682 9774541 T79703 T96307AL079725
454037 9962871 AW998716 AW022148 N68020
454096 10074491 AW062757 AW176890 AW062758 AW176895 AW176869 AW176900 AW176897 AW176928 AW176868 AW176892
454171 10492401 AW854832 AW854798 AW854857 AW854816 AW854834 AW854817
454457 12072741 AW753456 AW753036 AW854868 AW854862
454665 12285991 AW812866 AW812746 AW812747 AW812884 AW812763 AW812722
454860 12377321 AW835767 AW835537 BE160187
454968 12470291 AW849046 AW847956 AW849039 AW847957 AW848279 AW848698 AW849034 AW849033
455067 12520501 AW854538 AW854418 AW854412
455276 1272541 1 BE176479 BE176678 BE176357 BE176550 AW886079 BE176676 BE176615 BE176555 BE176489 BE176610 BE176362
455646 13485571 BE064420 BE064435 BE064429 BE064414 BE064400 BE064517
455710 13523681 BE072049 BE069471 BE069489 BE069478 BE069479 BE069492 BE069485 BE072122 BE072124 BE069491 BE069486 BE069464
457374 3287581 AA493662 AW897396 BE154814
458912 8231041 AI911066 AI933734 AI680888 AJ003599
TABLE 66C
Pkey Unique number correεponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489-495
Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
400533 6981826 Minus 277132-277595
400746 7329328 Minus 147703-147896
401132 8705350 Minus 8567985795
402145 8018280 Plus 113086-114800
403242 7637817 Minus 11297-12511
403481 9965004 Plus 93496-93633
403510 7652047 Pluε 61866-62027
403667 6850483 Minuε 1344-1442,1545-1697
404003 8655948 Plus 198349-199096
404561 9795980 Minus 69039-70100
404592 9943965 Minus 39067-39225
404848 8248647 Minus 23955-24034,25143-25264
404967 7523744 Minus 89944-90729
404995 6006247 Minus 154015-154123
405264 7329374 Plus 28556-28684
405321 3419846 Minus 44654-45210
405348 2914717 Minus 4331043462
405510 7630909 Minus 101028-101174
405548 1532158 Plus 11552-11686
TABLE 67A 689 GENES UP-REGULATED IN PROSTATE CANCER COMPARED TO NORMAL ADULT TISSUES
Table 67A lists about 689 genes up-regulated in proεtate cancer compared to normal adult tissues These were εelxted from 9009 probeεets on the Affymetπx/Eos Hu03 GeneChip array that showed some expression in human xenograft tumors and cell lines The 689 genes were selected such that the ratio of "average" prostate cancer to "average" normal adult tissues was greater than or equal to 25 The "average" prostate cancer level was set to the 75th percentile amongst prostate cancers The "average" normal adult tiεεue level waε εet to the 85th percentile amongst non-malignant tissues In order to remove gene specific background levels of non-spxific hybndization, the 10th percentile value amongst non- maligπant fissues was subtracted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number ExAccn Exemplar Accession number, Genbank accession number UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of tumor to normal body tissue Pkey ExAccn UnigenelD Unigene Title R1
448999 AF179274 Hs 22791 tranεmembrane protein with EGF-like and 732
426747 AA535210 Hs 171995 kallikrein 3, (prostate specific antigen 650
432441 AW292425 Hs 163484 ESTs 560
446057 AI420227 Hs 149358 Trp p8 tranεient receptor potential cati 550
400302 N48056 Hs 283946 folate hydrolase (prostate specific me b 48 1
414569 AF109298 Hs 118258 prostate cancer asεociated protein 1 41 4
432240 AI694767 Hs 129179 Homo sapiens cDNA FLJ13581 fis clone PL 403
419526 AI821895 Hs 193481 ESTε 359
400298 AA032279 Hs 61635 εix transmembrane epithelial antigen of 357
400299 X07730 Hs 171995 kallikrein 3 (prostate εpecific antigen 34 9
453370 AI470523 Hs 139336 ATP binding caεεette, sub family C (CFTR 339
409731 AA125985 Hs 56145 thymosm beta identified in neuroblast 32 8
424099 AF071202 Hs 139336 ATP binding cassette, sub family C (CFTR 32 6
400292 AA250737 Hs 72472 BMP R1B 28 8
400287 S39329 Hs 181350 kallikrein 2 prostate 288
425075 AA506324 Hs 1852 xid phosphatase, prostate 286
409361 NM 005982 Hs 54416 εme xulis homeobox (Drosophila) homolo 27 8
415539 AI733881 Hs 72472 BMP R1B 270
428819 AL135623 Hs 193914 KIAA0575 gene product 25
409262 AK000631 Hs 52256 hypothetical protein FLJ 20624 25 5
432374 W68815 Hs 301885 Homo sapieπε cDNA FLJ11346 fis, clone PL 248
407168 R45175 Hs 117183 ESTs 245
400296 AA305627 Hs 139336 ATP-bmding casεette, εub family C (CFTR 236
428336 AA503115 Hs 183752 microsemiπoprotein beta 23 5
433043 W57554 Hs 125019 lymphoid nuclear protein (LAF-4) mRNA 234
403047 NM_005656* Homo εapienε tranεmembrane pr 234
444484 AK0021 6 Hs 11260 hypothetical protein FLJ11264 220
423073 BE252922 Hs 123119 MAD (motherε againεt dxapentaplegic Dr 21 6
407709 AA456135 Hs 23023 ESTε 21 5
401424 NM.001172 Homo sapiens argmase, type ll 20 6
448290 AK002107 Hs 20843 Homo εapienε cDNA FLJ11245 fis clone PL 197
434666 AF151103 Hs 112259 T cell rxeptor gamma locus 18 5
415989 AI267700 ESTs 179
437052 AA861697 Hs 120591 ESTs 178
451939 U80456 Hs 27311 single minded (Drosophila) homolog 2 168
431548 AI834273 Hs 9711 novel protein 166
425628 NM 004476 Hε 283946 folate hydrolase (prostate spxific memb 165
428862 NM 000346 Hε 2316 SRY (sex determining region Y) box 9 (ca 16 5
450096 AI682088 Hε 79375 holxarboxylase synthetase (biotin [prop 165
413597 AW302885 Hε 117183 ESTs 161
411096 U80034 Hs 68583 mitochondnal intermediate peptidase 157
435677 AA694142 Hs 293726 ESTs, Weakly similar to TSGA RAT TESTIS 153
419743 AW408762 Hs 5957 Homo sapiens clone 24416 mRNA sequence 153
407122 H20276 Hs 31742 ESTs 15 1
427958 AA418000 Hs 98280 potassium intermediate/small conductance 141
418829 AA516531 Hs 55999 NK homeobox (Droεophila), family 3, A 139
426501 AW043782 Hs 293616 ESTε 139
428898 AB033070 Hs 194408 KIAA1244 protem 137
418961 AW967646 Hs 23023 ESTε 133
448519 AW175665 Hs 278695 Homo sapiens prostem mRNA, complete eds 132
418848 AI820961 Hs 193465 ESTs 131
428398 AI249368 Hs 98558 ESTs 130
429220 AW207206 ESTs 127
401451 NM.004496* Homo εapienε hepatxyte nude 124
424012 AW368377 Hs 137569 tumor protein 63 kDa with εtroπg homolog 124
419078 M93119 Hs 89584 mεulinoma-aεεxiated 1 123
450382 AA397658 Hs 60257 Homo sapiens cDNA FU13598 fiε, clone PL 11 9
430376 AW292053 Hs 12532 chromosome 1 open reading frame 21 11 8
408826 AF216077 Hs 48376 Homo sapienε clone HB-2 mRNA εequence 11 4
429918 AW873986 Hs 119383 ESTε 11 3
427212 AW293849 Hs 58279 ESTε, Weakly similar to ALU7 HUMAN ALU S 11 1
412446 AI768015 ESTs 11 1
433404 T32982 ESTs 109
420757 X78592 Hs 99915 androgen rxeptor (dihydrotestoεterone r 109
427674 NM 003528 Hε 2178 H2B histone family, member Q 106
444151 AW972917 Hs 128749 alpha-methylxyl CoA race aεe 104
447342 AI199268 Hs 19322 Homo εapiens, Similar to RIKEN cDNA 2010 103
418278 AI088489 Hs 83937 hypothetical protein 10 3
430226 BE245562 Hs 2551 adrenergic, beta-2 , rxeptor, surface 102
433927 AI557019 Hs 116467 small nuclear protein PRAC 102
408000 L11690 Hs 198689 bullous pemphigoid antigen 1 (230/240kD) 10 1
449625 NM.014253 odz (odd Oz/ten m, Drosophila) homolog 1 101
431117 AF003522 Hs 250500 delta (Drosophila) like 1 100
439444 AI277652 Hs 54578 ESTs Weakly similar to I38022 hypotheti 98
437718 AI927288 Hs 196779 ESTs 98
440529 AW207640 Hs 16478 Homo sapienε cDNA FLJ21718 fis, clone C 97
453160 AI263307 H2B histone family, member L 97
432715 AA247152 Hs 200483 ESTs Weakly similar to KIAA1074 protein 97
450325 AI935962 Hs 91973 ESTs 96
434170 AA626509 Hε 122329 ESTs 96
428600 AW863261 Hε 138860 hypothetical protein DKFZp434K1421 96 447033 AI357412 Hs 157601 ESTε 95
401747 Homo εapienε keratin 17 (KRT17) 93
434423 NM.006769 Hs 3844 LIM domain only 4 93
411887 AW182924 Hε 128790 ESTε 92
457211 AW972565 Hs 32399 ESTε, Weakly similar to S51797 vasodilat 92
415263 AA948033 Hs 130853 ESTs 92
432729 AK000292 Hs 130732 hypothetical protein FLJ20285 92
421896 N62293 Hs 45107 ESTs 9 1
432101 AI918950 Hs 123642 EphA3 9 1
451640 AA195601 Hs 26771 Human DNA sequence from clone 747H23 on 90
428046 AW812795 Hs 337534 ESTs, Moderately similar to I38022 hypot 89
420218 AW958037 ribosomal protein L4 88
434926 BE543269 Hs 50252 mitochondnal πbosomal protein L32 86
424692 AA429834 Hs 151791 KIAA0092 gene product 86
417333 AL157545 Hs 173179 bromodomam and PHD finger containing 3 86
452594 AU076405 Hs 29981 εolute earner family 26 (sulfate transp 85
446100 AW967109 Hs 13804 hypothetical protein dJ4620232 85
400294 N95796 Hs 278695 Homo sapiens prostem mRNA, complete eds 85
416182 NM 004354 Hs 79069 cyclin G2 85
431542 H63010 Hs 5740 ESTs 84
447397 BE247676 Hs 18442 E-1 enzyme 83
432674 AA641092 Hs 257339 ESTs, Weakly εimilar to I38022 hypotheti 8 1
456660 AA909249 Hs 112282 solute carrier family 30 (zinc transport 8 1
443822 AI087412 Hs 143611 ESTs, Weakly similar to 2004399A chromos 8 1
451684 AF216751 Hs 26813 CDA14 81
437124 AA554458 KIAA0666 protein 80
416239 AL038450 Hs 48948 ESTε 80
432415 T16971 Hs 289014 ESTε, Weakly similar to A43932 mucin 2 p 79
424800 AL035588 Hs 153203 MyoD family inhibitor 79
428728 NM.016625 Hs 191381 hypothetical protein 79
418564 AA631143 Hs 278695 Homo sapienε prostem mRNA, complete cdε 78
442049 AA310393 Hs 190044 ESTε 78
429597 NM 003816 Hs 2442 a disintegnn and metalloproteinase doma 78
410889 X91662 Hs 66744 twist (Drosophila) homolog (acrocephalos 77
443180 R15875 Hs 258576 claudin 12 75
433285 AW975944 Hs 237396 ESTs 75
410870 U81599 Hs 66731 homx box B13 74
418836 AI655499 Hs 161712 ESTs 74
444922 AI921750 Hs 144871 Homo sapiens cDNA FLJ13752 fis, clone PL 73
431992 NM 002742 Hε 2891 protein kinase C, mu 73
425905 AB032959 Hε 318584 novel C3HC4 type Zinc finger (nng finge 73
432586 AA568548 ESTs 73
431325 AW026751 Hs 5794 ESTs, Weakly similar to 2109260A B cell 73
435047 AA454985 Hs 54973 cadheπn-like protein VR20 73
447476 BE293466 Hs 20880 ESTs, Weakly similar to I38022 hypotheti 73
422728 AW937826 Hs 103262 ESTε, Weakly similar to ZN91.HUMAN ZINC 72
426108 AA622037 Hs 166468 programmed cell death 5 7 1
433323 AA805132 Hs 159142 ESTs 71
423349 AF010258 Hs 127428 hom∞ box A9 70
416815 U41514 Hs 80120 UDP-N acetyl alpha-D-gatxtosamine polyp 69
425154 NM 001851 Hs 154850 collagen, type IX, alpha 1 69
438869 AF075009 gb Homo εapienε full length insert cDNA 69
418329 AW247430 Hs 84152 cystathionme-beta-εynthaεe 68
452367 U71207 Hs 29279 eyeε absent (Drosophila) homolog 2 68
418601 AA279490 Hs 86368 calmegm 68
429769 NM 004917 ' Hs 218366 kallikrein 4 (prostase, enamel matnx, p 68
436962 AW377314 Hs 5364 DKFZP564I052 protein 68
425465 L18964 Hs 1904 protein kinase C, iota 66
450377 AB033091 KIAA1265 protein 66
451418 BE387790 Hε 26369 hypothetical protein FLJ20287 66
418250 U29926 Hε 83918 adenosme monophosphate deammase (isofo 66
416111 AA033813 Hs 79018 chromatin asεembly fxtor 1 , εubumt A ( 65
426350 NM 003245 Hs 2022 transglutaminase 3 (E polypeptide, prote 65
440774 AI420611 Hs 153934 ESTs 65
413992 W26276 Hs 136075 RNA, U2 small nuclear 64
421928 AF013758 Hs 109643 polyadenylate binding protein mteractin 64
433293 AF007835 Hs 32417 hypothetical protein MGC4309 64
452340 NM.002202 Hs 505 ISL1 transcnption factor, UM/homxdoma 64
451027 AW519204 Hε 40808 ESTs 64
436063 AK000028 πbosomal protein S24 63
440749 W22335 Hs 7392 hypothetical protein MGC3199 63
432103 T15803 Hε 272458 protein phosphatase 3 (formerly 2B), cat 63
431958 X63629 Hε 2877 cadhenn 3, type 1, P-cadheπn (plxenta 62
411019 AW993097 Hε 48617 Homo sapiens cD A FLJ 12540 fis, clone NT 62
421566 NM 000399 Hs 1395 early growth response 2 (Krox-20 (Drosop 62
452744 AI267652 Hs 246107 Homo sapiens mRNA, cDNA DKFZp434E082 (fr 6 1
425259 AL049280 Hs 155397 Homo sapiens mRNA, cDNA DKFZp564K143 (fr 61
442772 AW503680 Hs 5957 Homo sapiens clone 24416 mRNA sequence 61
448045 AJ297436 Hs 20166 prostate stem cell antigen 60
428342 AI739168 Homo sapienε cDNA FLJ 13458 fis, clone PL 60
453439 AI572438 Hs 32976 guanine nucleotide binding protein 4 60
433517 AW022133 Hε 189838 ESTs 60
424036 AA770688 H2A histone family member L 59 420092 AA814043 Hs 88045 ESTs 59
410268 AA316181 Hs 61635 εix transmembrane epithelial antigen of 58
425071 NM 013989 Hs 154424 deiodmase, lodothyronine, type II 58
441866 BE464341 Hs 21201 nectm 3, DKFZP566B0846 protein 58
450244 AA007534 Hs 125062 ESTs 58
429165 AW009886 Hs 118258 prostate cancer assxiated protein 1 57
451952 AL120173 Hs 301663 ESTs 57
429084 AJ001443 Hs 195614 splicing factor 3b, subunit 3, 130kD 57
445873 AA250970 Hs 251946 poly(A) binding protein, cytoplasmic 1-1 57
412935 BE267045 Hs 75064 tubulin spxific chaperone c 57
415068 Z19448 Hs 131887 ESTs, Weakly similar to T24396 hypotheti 57
434826 AF155661 Hs 22265 pyruvate dehydrogenase phosphatase 57
415621 AI648602 Hs 55468 ESTs 57
416653 AA768553 Hs 193145 metallothionein 1E (functional) 56
433332 AI367347 Hs 44898 Homo sapienε clone TCCCTA00151 mRNA εequ 55
455497 AA112573 Hs 278695 Homo sapiens prostem mRNA, complete cdε 55
418245 AA088767 Hs 83883 tranεmembrane, prostate androgen induced 54
428593 AW207440 Hs 185973 degenerative spermatocyte (homolog Droso 54
425211 M18667 Hs 1867 progastπcsin (pepsinogen C) 54
456508 AA502764 Hs 123469 ESTs, Weakly similar to AF208855 1 BM 01 54
458809 AW972512 Hs 20985 sιn3 associated polypeptide 30kD 54
410762 AF226053 Hs 66170 HSKM B protein 54
440594 AW445167 Hs 126036 ESTε 54
413328 Y15723 Hs 75295 guanylate cyclaεe 1, soluble, alpha 3 53
447805 AW627932 Hs 302421 gemιn4 53
434808 AF155108 Hε 256150 Homo sapiens Similar to RIKEN cDNA 2810 53
453308 AW959731 Hε 323099 ESTs 53
421470 R27496 Hs 1378 annexm A3 53
418555 AI417215 Hs 87159 hypothetical protein FLJ12577 52
404632 NM 022490 Homo sapiens hypothetical prot 5 1
450861 AI523898 Hs 17617 ESTs 51
431583 AL042613 Hs 262476 S-adenosylmethioπine decarboxylaεe 1 5 1
400303 AA242758 Hs 79136 UV-1 protein, eεtrogen regulated 5 1
400290 H18836 Hs 31608 hypothetical protein FLJ20041 51
410037 AB020725 Hs 58009 KIAA0918 protein 5 1
410240 AL157424 Hs 61289 εyπaptojaπin 2 50
403046 NM.005656* Homo εapienε transmembrane pr 50
419647 AA348947 Hs 91816 hypothetical protein 50
450203 AF097994 L-kynurenine/alpha-aminoadipate ammotra 50
450164 AI239923 Hs 63931 ESTs 50
417318 AW953937 Hs 240845 ESTs 49
417153 X57010 Hs 81343 collagen, type II, alpha 1 (pπmary oste 49
412350 AI659306 Hs 73826 protein tyrosine phosphatase, non rxept 49
456088 BE177320 Hs 156148 hypothetical protein FLJ13231 49
433852 AI378329 Hs 126629 ESTs 49
452679 Z42387 Hs 83883 transmembrane, prostate androgen induced 49
430387 AW372884 Hs 240770 nuclear cap binding protein subunit 2, 2 49
416276 U41060 Hs 79136 UV-1 protein, estrogen regulated 48
441021 AW578716 Hs 7644 H1 histone family, member 2 48
453171 R76472 Hε 65646 ESTs 48
416795 AI497778 Hs 20509 HBV pX asεociated proteιn-8 48
427615 BE410107 Hs 179817 CGI-82 protein, PSDR1 48
419440 AB020689 Hs 90419 KIAA0882 protein 48
422048 NM 01244E i Hs 288126 spondin 2, extrxellular matnx protem 48
453082 H18835 Hs 31608 hypothetical protein FU20041 48
420948 AB016898 Hs 100469 myeloid/lymphoid or mixed-lineage leukem 48
442592 BE566623 Hs 29899 ESTs, Weakly similar to G02075 traπscπp 48
421685 AF189723 Hs 106778 ATPase, Ca transporting, type 2C, member 47
431724 AA514535 Hs 283704 ESTs 47
423242 AL039402 Hs 125783 DEME-6 protein 47
434485 AI623511 Hs 118567 ESTs 47
407103 AA424881 Hs 256301 hypothetical protein MGC13170 46
414085 AA114016 Hs 75746 aldehyde dehydrogenase 1 family, member 46
422486 BE514492 Hε 117487 gene near HD on 4p163 with homology to 46
422083 NM 00114" 1 Hs 111256 arxhidonate 15-lιpoxygenase, sxond typ 46
439735 AI635386 Hs 142846 hypothetical protein 46
420039 NM.004605 Hε 94581 εulfotraπεferase family, cytosolic, 2B, 46
449845 AW971183 Hs 6019 DnaJ (Hsp40) homolog, εubfamily C, membe 45
423445 NM.014324 Hε 128749 alpha-methylxyl CoA rxemase 45
433730 AK002135 Hs 3542 hypothetical protein FU11273 45
426006 R49031 Hε 22627 ESTs 45
451982 F13036 Hs 27373 Homo sapienε mRNA, cDNA DKFZp56401763 (f 45
415082 AA160000 Hs 137396 ESTs, Weakly similar to JC5238 galxtosy 45
409799 D11928 Hs 76845 phosphoseπne phosphatase-like 45
423583 AL122055 Hs 129836 KIAA1028 protein 44
452017 AF109302 Hs 27495 prostate cancer assxiated protein 7 44
437162 AW005505 Hs 5464 thyroid hormone receptor coactivating pr 44
451468 AW503398 Hs 293663 ESTs, Moderately εimilar to I38022 hypot 44
429467 NM 004477 Hs 203772 FSHD region gene 1 44
451752 AB032997 KIAA1171 protein 43
430294 AI538226 Hs 32976 guanine nucleotide binding protein 4 43
452259 AA317439 Hs 28707 signal sequence receptor, gamma (translo 43
456362 AW973002 I Hs 179909 hypothetical protein FLJ22995 43 449048 Z45051 Hs 22920 similar to S68401 (cattle) glucose indue 43
440300 N39760 Hs 8859 Homo sapienε Similar to RIKEN cDNA 5830 43
427308 D26067 Hs 174905 KIAA0033 protein 43
435706 W31254 Hs 7045 GL004 protein 43
416854 H40164 Hs 80296 Purkinje cell protem 4 42
451406 AI694320 Hs 6295 ESTε Weakly similar to T17248 hypotheti 42
410076 T05387 Hs 7991 ESTs 42
410275 U85658 Hs 61796 transcription factor AP 2 gamma (activat 42
419239 AA468183 Hs 184598 Homo sapiens cDNA FLJ23241 fis clone C 42
442501 AA315267 Hs 23128 ESTs 42
436761 AI817776 Hs 236557 ESTs 42
420380 AA640891 Hs 102406 ESTs 42
436556 AI364997 Hs 7572 ESTs 42
458440 A1095468 Hs 135254 Homo sapiens clone 1 thrombospondm mRNA 42
446416 AV658299 Hs 163959 ESTs 42
417873 BE266659 Hs 293659 Homo sapiens Similar to RIKEN cDNA A430 42
430598 AK001764 Hs 247112 hypothetical protein FLJ10902 4 1
421305 BE397354 Hs 324830 diptheπa toxin resiεtance protein requi 4 1
429299 AI620463 Hs 347408 hypothetical protein MGC13102 4 1
407894 AJ278313 Hs 41143 phosphoinositide-specific phospholipase 41
414664 AA587775 Hs 66295 ulti PDZ-domain containing protein 41
408418 AW963897 Hs 44743 KIAA1435 protein 4 1
430945 U80669 Hs 55999 NK homeobox (Drosophila) family 3 A 4 1
432363 AA534489 gb nf76g11 s1 NCI_CGAP_Co3 Homo sapiens 4 1
447574 AF162666 Hs 18895 tousled like kinase 1 40
447595 AW379130 Hs 18953 phoεphodiesterase 9A 40
453857 AL080235 Hs 35861 DKFZP586E1621 protein 40
444108 R55784 Hs 140942 ESTs 40
422890 Z43784 aπkyπn 3 node of Ranvier (ankyrm G) 40
417379 AA196390 gb zp99b10 s1 Stratagene muscle 937209 H 40
418818 AA228899 Hs 101307 Homo sapiens HUT11 protein mRNA partial 40
410102 AW248508 Hs 279727 ESTs homologue of PEM 3 [Cioπa εavignyi 40
418821 AA436002 Hs 183161 ESTε 40
438825 BE327427 Hs 79953 ESTε 40
433233 AB040927 Hs 301804 KIAA1494 protein 40
415276 U88666 Hs 78353 SFRS protein kinase 2 40
440146 AW014231 Hs 90790 Homo sapiens cDNA FU22930 fis clone K 40
407819 R42185 ESTs 40
450402 BE218027 Hs 89969 ESTs 40
432527 AW975028 Hs 102754 ESTs 40
419733 AW362955 Homo sapienε cDNA FLJ14415 fis clone HE 39
422134 AW179019 Hs 112110 mitxhondπal πbosomal protein L42 39
432435 BE218886 Hs 282070 ESTs 39
450680 AF131784 Hs 25318 Homo sapiens clone 25194 mRNA sequence 39
436420 AA443966 Hs 31595 ESTs 39
430122 NM 013342 Hs 233765 TCF3 (E2A) fusion partner (in childhood 39
411031 W37943 Hs 34892 KIAA1323 protein 39
429259 AA420450 Hs 292911 Plakophilin 39
407813 AL120247 Hs 40109 KIAA0872 protein 39
417067 AJ001417 Hs 81086 εolute earner family 22 (extraneuronal 39
410227 AB009284 Hs 61152 exostoses (multiple) like 2 39
417958 AA767382 Hs 193417 ESTε 39
427176 AW381569 Hs 40334 ESTε 39
448826 AI580252 Hs 293246 ESTs Weakly similar to putative p150 [H 38
447966 AA340605 Hs 105887 ESTs Weakly similar to Homolog of rat Z 38
432675 AI791855 ESTs 38
419713 AW968058 Hs 92381 nudix (nucleoside diphosphate linked mot 38
427479 BE410092 Hs 178471 KIAA0798 gene product 38
443162 T49951 Hs 9029 DKFZP434G032 protein 38
413950 AA249096 Hε 32793 ESTs 38
439963 AW247529 Hs 6793 platelet xtivatmg fxtor xetylhydrola 38
419083 AI479560 Hε 98613 Homo sapiens cDNA FLJ12292 fis clone MA 38
448148 NM 016578 Hs 20509 HBV pX asεxiated protein 8 38
419465 AW500239 Hε 21187 Homo εapienε cDNA FU23068 fiε clone L 38
432274 AK000382 Hε 274251 hypothetical protein FU20375 KIAA1797 38
447620 AW290951 ESTε 38
430589 AJ002744 Hε 246315 UDP N xetyl alpha-D-galxtosamine polyp 38
418004 U37519 Hε 87539 aldehyde dehydrogenase 3 family member 38
416655 AW968613 Hs 79428 BCL2/adenovιrus E1B 19kD interxting pro 38
459284 AF155660 Hs 300496 mitxhondπal εolute earner 38
421829 AB018330 Hs 108708 calcium/calmodulin dependent protem km 37
437252 AI433833 Hs 164159 ESTε Weakly εimilar to ALULHUMAN ALU S 37
437967 BE277414 Hs 5947 el transforming oncogene (denved from 37
417061 AI675944 Hs 188691 Homo sapienε cDNA FLJ12033 fis clone HE 37
423337 NM.004655 Hs 127337 axin 2 (conduct axil) 37
418838 AW385224 Hs 35198 xtonuclxtide pyrophosphatase/phosphodi 37
453469 AB014533 Hs 33010 KIAA0633 protein 37
408063 BE086548 Hs 42346 calcineuπn binding protein calsarcm 1 37
422072 AB018255 Hs 111138 KIAA0712 gene product 37
420297 AI628272 Hs 88323 ESTs Weakly similar to ALULHUMAN ALU S 37
420522 AW957137 ■ Hs 98541 hypothetical protein 36
408833 AW612232 I Hs 254835 ESTs 36
426647 AA243464 Hs 294101 pre B cell leukemia transcription factor 36 456177 NM 012391 Hs 79414 prostate epithelium specific Ets transcr 36
425689 W16480 Hs 24283 ESTs, Moderately similar to reduced expr 36
432370 AA308334 Hs 274424 N acetylneurammic acid phosphate syntha 36
422424 AI186431 Hs 296638 prostate differentiation factor 36
446157 BE270828 Hs 131740 Homo sapiens cDNA FLJ22562 fis, clone H 36
433339 AF019226 Hs 8036 glioblastoma overexpressed 36
421887 AW161450 Hs 109201 CGI-86 protein 36
435114 AA775483 Hs 288936 mitochondnal ribosomal protein L9 36
412520 AA442324 Hs 795 H2A histone family, member O 36
436476 AA326108 Hs 33829 bHLH protein DEC2 36
441224 AU076964 Hs 7753 calumeπin 35
404922 NM.003071 Homo sapienε SWI/SNF related 35
432278 AL137506 Hs 274256 hypothetical protein FLJ23563 35
452747 BE153855 Hs 61460 Ig superfamily receptor LNIR 35
429686 AI871613 Hs 28538 Homo sapiens cDNA FLJ21086 fis, clone C 35
408001 AA046458 Hs 95296 ESTs 35
428330 L22524 Hs 2256 matrix metalloprotemase 7 (matπlysin, 35
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 35
428055 AA420564 Hs 101760 ESTε 35
418827 BE327311 Hs 47166 HT021 35
431103 M57399 Hs 44 pleiotrophm (hepaπn binding growth fx 35
427701 AM11101 Hs 243886 nuclear auloantigenic εperm protein (his 35
419168 AI336132 Hs 33718 Homo sapieπε cDNA FU 12641 fiε, clone NT 35
409151 AA306105 SEC22, veεicle trafficking protein (S c 35
439671 AW162840 Hs 6641 kinesm family member 5C 34
452721 AJ269529 Hs 301871 solute carrier family 37 (glycerol 3 pho 34
449933 AW157098 Hs 324104 Human DNA sequence from clone RP1-63M2 o 34
432615 AA557191 Hs 55028 ESTs, Weakly similar to I54374 gene NF2 34
443884 N20617 Hs 194397 leptin receptor 34
403752 NM.002753* Homo sapiens mitogen-acfivate 34
427723 AI355260 Hs 279789 histone deacetylase 3 34
421878 AA299652 Hs 111496 Homo εapiens cDNA FLJ11643 fis, clone HE 34
440494 BE618768 Hs 7232 acetyl Coenzyme A carboxylase alpha 34
426716 NM.006379 Hs 171921 sema domain, immunoglobulin domain (Ig), 34
433647 AA603367 Hs 222294 ESTs 34
407137 T97307 gb ye53h05 ε1 Soareε fetal liver spleen 34
432886 BE159028 Hs 279704 chromatin accessibility complex 1 34
427715 BE245274 Hs 180428 KIAA1181 protein 33
437617 AI026701 Hs 5716 KIAA0310 gene product 33
447818 W79940 Hs 21906 Homo sapiens clone 24670 mRNA sequence 33
414407 AA147026 Hs 76704 ESTs 33
421537 BE383488 Hs 105547 neural proliferation, differentiation an 33
435655 AW105663 Hs 6947 HSPC069 protein 33
427871 AW992405 Hs 59622 Homo sapiens, clone IMAGE 3507281, mRNA, 33
421662 NM.014141 Hs 106552 cell recognition molxule Caspr2 33
407204 R41933 Hs 140237 ESTε, Weakly similar to ALULHUMAN ALU S 33
407908 BE379758 Hs 110853 uncharacteπzed hematopoietic stem/proge 33
407846 AA426202 Hs 40403 Cbp/p300-ιnteractιπg tranεxtivator, wit 33
420568 F09247 Hs 247735 protocadhenn alpha 10 33
436873 N23874 Hs 50477 RAB27A, member RAS oncogene family 33
411145 BE439553 Hs 250528 Homo sapiens, clone IMAGE 4098694, mRNA, 33
435017 AA336522 Hs 12854 angiotensin II, type I rxeptor-assxiat 33
435020 AW505076 Hs 301855 DiGeorge syndrome critical region gene 8 33
443991 NM 00225C i Hs 10082 potassium intermediate/small conductance 33
409960 BE261944 hexokmase 1 33
433891 AA613792 gb no97h03 s1 NCI CGAP_Pr2 Homo sapiens 33
430389 AL117429 Hs 240845 DKFZP434D146 protein 33
432242 AW022715 Hs 162160 ESTs, Weakly similar to ALU4.HUMAN ALU S 33
419972 AL041465 Hs 182982 golgm 67 33
445707 AI248720 Hs 114390 ESTs 33
412628 AI972402 Hs 306051 hypothetical protein MGC2648 33
425263 NM.001197 ' Hs 155419 BCL2 interxting killer (apoptosis-induc 33
419879 Z17805 Hs 93564 Homer, neuronal immediate eariy gene, 2 33
433345 AI681545 Hs 152982 hypothetical protein FLJ 13117 33
417515 L24203 Hε 82237 ataxia telaπgixtasia group D-ass∞iated 33
414922 D00723 glycine cleavage syεtem protein H (ammo 33
437898 W81260 Hs 43410 ESTε 32
426126 AL118747 Hs 26691 ESTs 32
422089 AA523172 Hs 103135 ESTs, Weakly similar to SFR4_HUMAN SPLIC 32
450649 NMJ01429 Hs 25272 E1A binding protein p300 32
404210 NMJW5936 Homo sapiens myeloid/lymphoid 32
434954 AF161455 Hs 284295 Homo sapiens HSPC337 mRNA partial eds , 32
401519 C15000476* gι|12737279|ref|XP_012163 1| 32
419517 AF052107 Hs 90797 Homo sapiens clone 23620 mRNA sequence 32
431585 BE242803 Hs 262823 hypothetical protein FLJ 10326 32
427461 AA531527 Hs 332040 hypothetical protem MGC13010 32
453288 AW583292 Hs 274412 similar to yeast Upf3, vanant A 32
412513 AA322599 Hs 5163 ESTs, Weakly similar to AF151840 1 CGI 8 32
432579 AF043244 Hε 278439 nucleolar protein 3 (apoptosis represεor 32
439593 BE073597 Hs 124863 ESTε 32
451945 BE504055 Hs 211420 ESTε 32
434614 AI249502 Hs 29669 ESTε 32
445525 BE149866 Hs 14831 Homo sapiens, Similar to zinc finger pro 32 419991 AJ000098 Hs 94210 eyes absent (Drosophila) homolog 1 32
408101 AW968504 Hs 123073 CDC2 related protein kinase 7 32
425810 AI923627 Hs 31903 ESTs 32
443123 AA094538 Hs 272808 putative transcription regulation nuclea 32
447439 AA313565 Hs 145020 ESTs, Weakly similar to KIAA1205 protein 32
452167 N75238 Hs 13075 Homo sapiens cDNA FLJ23013 fis, clone L 31
440789 AB007857 Hs 7416 KIAA0397 gene product 31
436087 BE300296 Hs 5054 CGI-133 protein 31
414222 AL135173 sorbitol dehydrogenase 31
419749 X73608 Hs 93029 sparc/osteonectin, cwcv and kazal like d 31
418559 AA225048 Hs 104207 ESTs 31
408784 AW971350 Hs 63386 ESTs 31
424285 BE207168 Hs 144630 nuclear rxeptor subfamily 2, group F, m 31
417193 AI922189 Hs 288390 hypothetical protein FLJ22795 31
428738 NM 000380 Hs 192803 xeroderma pigmentosum, complementation g 31
436489 AJ272269 Hs 121429 zinc-binding protein Rbcc728 31
433006 BE242758 Hs 190223 ESTs, Moderately similar to T29285 hypot 31
426991 AK001536 Homo sapienε cDNA FLJ10674 fiε, clone NT 31
445943 AW898533 Hs 181574 ESTε 31
434194 AF119847 Homo sapiens PRO1550 mRNA, partial eds 31
432426 AW973152 Hs 31050 ESTs 31
416974 AF010233 Hs 80667 RALBP1 assxiated Eps domain containing 31
451131 AI267586 Hs 268012 fatty acid Coenzyme A ligase, long chain 31
423453 AW450737 Hs 128791 CGI-09 protein 31
417215 BE253181 Hs 81687 non metastatic cells 3, protein expresεe 31
436278 BE396290 Hs 5097 εynaptogyπn 2 31
432908 AI861896 ESTs 31
432952 AA813887 Hs 188173 Homo sapienε cDNA FLJ12187 fis clone MA 31
438705 AI049624 Hs 283390 ESTε, Weakly similar to 2109260A B cell 31
427982 NM 016156 Hs 181326 KIAA1073 protein 31
431578 AB037759 Hs 261587 GCN2 elF2a!pfιa kinase 31
409757 NM 001898 Hs 123114 cystatiπ SN 31
407136 T64896 Hs 287420 Homo εapienε cDNA FLJ 1533 fis, clone HE 31
434293 NM 004445 Hs 3796 EphB6 31
410001 AB041036 Hs 57771 kallikrein 11 31
434970 AW272262 Hs 225767 ESTs 31
432800 BE391046 Hs 278962 AIM-1 protein 31
423392 AA195037 Hs 169341 HTPAP protein 31
432205 AI806583 Hs 125291 ESTs 31
448807 AI571940 Hs 7549 ESTs 31
439979 AW600291 Hs 6823 hypothetical protein FU 10430 31
435561 AA351978 Hs 4943 hepatxellular carcinoma asεxiated prot 30
427315 AA179949 Hs 175563 Homo sapiens mRNA cDNA DKFZp564N0763 (f 30
410082 AA081594 Hs 158311 Musaεhi (Drosophila) homolog 1 30
432621 AI298501 Hs 21192 ESTs, Weakly similar to T46428 hypotheti 30
429638 AI916662 Hs 211577 kiπectin 1 (kinesiπ receptor) 30
452908 AB001451 Hs 30965 neuronal She adaptor homolog 30
426030 BE243933 Hs 108642 zinc finger protein 22 (KOX 15) 30
407688 W25317 Hs 37616 Human D9 splice vaπant B mRNA, complete 30
434958 T99949 Hs 303428 Homo sapiens cDNA FU14832 fis, clone OV 30
418610 AW245993 Hs 223394 hypothetical protein MGC2742 30
451815 AW974911 Hs 184793 Homo sapienε cDNA FU21880 fis, clone H 30
433556 W56321 Hs 111460 calcium/calmodulin dependent protein km 30
413010 AA393273 Hs 75133 transcnption factor 6-lιke 1 (mitxhond 30
449459 BE546846 Hs 195048 ESTs 30
438523 H66220 Hs 278177 ESTs 30
434263 N34895 Hs 44648 ESTs 30
446825 BE266822 Hs 344097 filamin A, alpha (actin-bindmg protein- 30
408681 AW953853 Hs 292833 ESTε, Weakly similar to I38022 hypotheti 30
429966 BE081342 Hs 283037 HSPC039 protein 30
412652 AI801777 ESTs 30
442409 BE208843 Hs 129544 hypothetical protein MGC15438 30
450832 AW970602 Hs 105421 ESTs 30
440074 AA863045 Hs 10669 ESTs, Weakly similarto T00050 hypotheti 30
436032 AA150797 Hs 109276 latexin protein 30
419594 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 30
421674 T10707 Hs 296355 hypothetical protein FLJ23138 29
432302 AA345857 Hs 274307 KIAA1442 protein 29
415172 AF079529 Hs 78106 phosphodiesterase 8B 29
412926 AI879076 Hs 75061 mxrophage myπstoylated alanine-πch C 29
413142 M81740 Hs 75212 ornithine dxarboxylase 1 29
437179 AA393508 serologically defined colon cancer antig 29
418372 AA311833 Hs 84318 replication protein A1 (70kD) 29
439609 AW971945 Hs 293236 ESTε 29
427398 AW390020 Hs 20415 chromoεome 21 open reading frame 11 29
447958 AW796524 Hs 68644 Homo sapiens microsomal εignal peptidase 29
409340 BE174629 Hs 321130 hypothetical protem MGC2771 29
420061 AW024937 Hs 29410 ESTs 29
431663 NM 016569 Hs 267182 TBX3-ιso protem 29
417622 AW298163 Hs 82318 WAS protein family, member 3 29
420344 BE463721 Hs 97101 putative G protein-coupled rxeptor 29
446791 AI632278 Hs 195922 ESTs 29
433313 W20128 Hs 296039 ESTs 29 428465 AW970976 Hs 293653 ESTs 29
457489 AI693815 Hs 127179 cryptic gene 29
452092 BE245374 Hs 27842 hypothetical protein FLJ11210 29
446880 AI811807 Hs 108646 Homo sapienε cDNA FLJ 14934 fiε, clone PL 29
419829 AI924228 Hs 115185 ESTs, Moderately similar to PC4259 fern 29
437396 BE140396 Hs 21621 hypothetical protein DKFZp762O076 29
413125 BE244589 Hs 75207 glyoxalase I 29
401785 NM.002275* Homo sapiens keratin 15 (KRT1 29
433495 AW373784 Hs 1 alpha 2-glycoproteιn 1 , zinc 29
452099 BE612992 Hs 27931 hypothetical protein FLJ 10607 similar to 29
437296 AA350994 Hs 20281 KIAA1700 29
421254 AK001724 Hs 102950 coat protein gamma-cop 29
445109 AF039916 Hs 12330 ectonucleoside tπphosphate diphosphohyd 29
423551 M327598 Hs 89633 ESTs 29
421154 AA284333 Hs 287631 Homo sapienε cDNA FLJ 14269 fiε, clone PL 29
410193 AJ132592 Hs 59757 zinc finger protein 281 29
435854 AJ278120 Hs 4996 putative ankyπn-repeat containing prote 29
423396 AI382555 Hs 127950 bromodomain containing 1 28
442202 BE272862 Hs 106534 hypothetical protein FLJ22625 28
441345 AW068579 Hs 7780 Homo sapiens mRNA, cDNA DKFZp564A072 (fr 28
444367 H54892 Hs 10974 hypothetical protein FLJ22390 28
422522 AI023428 Hs 34549 ESTs, Highly similar to S94541 1 clone 4 28
443337 Y07604 Hs 9235 non metastatic cells 4, protein expresεe 28
418166 AI754416 Cdc42 effector protein 3 28
448734 BE614070 Hs 326416 Homo εapienε mRNA, cDNA DKFZp564H1916 (f 28
413550 W03011 Hs 306881 MSTP043 protein 28
426170 BE161065 Hs 167531 methylcrotonoyl Coenzyme A carboxylaεe 2 28
444101 R19175 Hs 169793 ribosomal protein L32 28
425320 U29344 Hs 83190 fatty acid synthaεe 28
431631 AA548906 Hs 122244 ESTε 28
448804 AW512213 Hs 342849 ADP πboεylation fxtor-like 5 28
431416 AA532718 ESTs 28
447881 . BE620886 GCN1 (general control of amino-xid synt 28
445309 AL157474 Hs 12504 likely ortholog of mouεe Arkadia 28
453186 AK001708 Hs 32271 hypothetical prote FLJ10846 28
439778 AL109729 Hs 99364 putative tranεmembrane protein 28
425010 T16837 Hs 4241 ESTε 28
432840 AK001403 Hs 279521 hypothetical protein FLJ20530 28
450546 AA010200 Hs 175551 ESTε 27
431674 M098901 Hs 301642 G-protein coupled receptor 27
422017 NM 003877 Hs 110776 STAT induced STAT ιnhιbιtor-2 27
443181 AI039201 Hs 283316 ESTε 27
448913 M194422 Hs 22564 myosin VI 27
440193 AW902312 Hs 7037 Homo εapiens clone 24923 mRNA εequence 27
452941 AL110347 Hs 31074 N sulfoglucosamine εulfohydrolase (sulfa 27
451338 AW612322 Hs 19131 transcnption factor Dp-2 (E2F dimeπzat 27
411190 AA306342 Hs 69171 protein kinase C-like 2 27
434629 M789081 Hs 4029 glioma amplified sequence-41 27
407192 M609200 gb af12e02 s1 Soares testis NHT Homo sap 27
434747 AA837085 ESTs 27
428171 M489323 Hs 182825 πbosomal protein L35 27
426657 NM 015865 i Hs 171731 solute camerfamily 14 (urea transport 27
447147 M910353 Hs 75432 ESTs, Weakly similar to T23482 hypotheti 27
452955 AW390282 Hs 31130 transmembrane 7 superfamily member 2 27
407748 AL079409 Hs 38176 KIAA0606 protein, SCN Orcadian Oscillat 27
445596 R89543 Hs 12942 veεicle trafficking protein 27
452268 NM 00351 J 1 Hε 28777 H2A histone family, member L 27
446494 AA463276 Hε 288906 WW Domain-Containing Gene 27
438157 AW137011 Hε 49576 ESTs 27
452260 AA453208 Hs 330994 RAB9, member RAS oncogene family 27
409648 AW451449 Hs 57749 ESTs 27
401866 Target Exon 27
400301 X03635 Hs 1657 estrogen rxeptor 1 27
453390 M862496 Hs 28482 ESTs 27
426514 BE616633 Hs 170195 bone morphogenetic protein 7 (osteogenic 27
425294 AF033827 Hs 155553 HNK-1 sulfotransferase 27
405387 NM.022170* Homo sapiens Williams Beuren 27
441266 H15968 Hs 293845 Homo sapienε, clone IMAGE 3502329, mRNA, 27
432388 X15218 Hs 2969 v-ski avian sarcoma viral oncogene homol 27
450937 R49131 Hs 26267 ATP-dependaπt interferon response protei 27
447210 AF035269 Hs 17752 phosphatidylεeπne-spxific phospholipas 27
445098 AL050272 Hs 12305 DKFZP566B183 protein 27
451404 AA460775 Hs 6295 ESTs, Weakly similar to T17248 hypotheti 27
409650 T08490 Hs 288969 HSCARG protein 27
452707 AI093823 Hs 45070 ESTs 27
451134 M318315 Hs 25999 hypothetical protein FLJ22195 27
452826 BE245286 Hs 301636 peroxiεomal biogenesis factor 6 27
420818 AW969635 Hs 33032 ESTs, Weakly εimilar to 1207289A reverεe 27
438510 AL080220 Hs 6285 DKFZP586P0123 protein 27
406627 T64904 Hs 163780 ESTs 27
442315 AA173992 Hs 7956 ESTs, Moderately similar to ZN91.HUMAN Z 27
421717 AF230924 Hs 107187 divalent cation tolerant protein CUTA 26
425910 M830797 Hs 184760 CCAAT-box binding transcnption factor 26 440695 AW088363 Hε 246240 ESTε 26
416941 BE000150 Hε 48778 niban protein 26
422717 AI557623 Hs 119475 cold inducible RNA binding protein 26
426110 NM 002913 Hs 166563 replication factor C (activator 1) 1 (14 26
422027 AL043100 Hs 306319 fatty acid amide hydrolaεe 26
401197 ENSP00000229263* HSPC213 26
442607 AA507576 Hs 288361 Homo εapienε cDNA FLJ22696 fis clone H 26
410297 AA148710 lumican 26
447963 AI452973 Hs 165900 ESTs Weakly similarto ALULHUMAN ALU S 26
433101 AW572317 Hs 12082 Homo sapiens mRNA cDNA DKFZp566L203 (fr 26
437546 AW074836 Hs 173984 T-box 1 26
443725 AW245680 Hs 9701 growth arrest and DNA damage inducible 26
436213 AA325512 Hs 71472 hypothetical protein FU10774, KIAA1709 26
408157 AA047685 Hs 62946 ESTs 26
420805 L10333 Hs 99947 reticulon 1 26
454144 BE280478 Hs 182695 hypothetical protein MGC3243 26
426761 AI015709 Hs 172089 Homo εapienε mRNA, cDNA DKFZp586l2022 (f 26
428695 AI355647 Hs 189999 puππergic rxeptor (family A group 5) 26
431725 X65724 Hs 2839 Nome diεeaεe (pseudoglioma) 26
425174 D87450 Hs 154978 KIAA0261 protein 26
410467 AF102546 Hs 63931 dachshund (Drosophila) homolog 26
413435 X51405 Hs 75360 carboxypeptidase E 26
428293 BE250944 Hs 183556 solute carrier family 1 (neutral am o a 26
428180 AI129767 Hs 182874 guanine nucleotide binding protein (G pr 26
439680 AW245741 Hs 58461 ESTs, Weakly similar to A35659 krueppel 26
424395 AA165082 Hs 146388 microtubule asεxiated protein 7 26
406670 W79632 Hs 256301 hypothetical protein MGC13170 26
413762 AW411479 Hs 848 FK506 binding protein 4 (59kD) 26
429922 Z97630 Hs 226117 H1 histone family, member 0 26
449518 BE395253 Hs 30861 ESTs 26
445919 T53519 Hs 334692 hypothetical protein MGC14141 26
429343 AK000785 Hs 199480 Homo εapienε, Similar to epsm 3 clone 26
438552 AJ245820 Hs 6314 type I transmembrane rxeptor (seizure r 26
431472 AK001023 Hs 256549 nucleotide binding protein 2 (E coli Mm 26
409299 AA045650 Hs 53125 small nuclear ribonucleoprotem D2 polyp 26
434672 AW294020 Hs 117721 ESTε 26
443015 R33261 Hs 6614 ESTε, Weakly similar to A43932 mucin 2 p 26
452576 AB023177 Hs 29900 KIAA0960 protein 26
412843 AF007555 Hs 74624 protein tyrosine phoεphataεe, rxeptor t 26
430375 AW371048 Hs 93758 H4 hiεtone family, member H 26
408196 AL034548 Hs 43627 SRY (sex determining region Y) box 22 26
424339 BE257148 endoglycan 26
416292 AA179233 Hs 42390 nasopharyngeal carcinoma susceptibility 26
451040 AA324743 Hs 40808 ESTs 26
445636 AW105401 πbosomal protein L29 26
419175 AW270037 KIAA0779 protem 26
422000 M30599 Hs 110637 homx box A10 26
441128 AA570256 ESTs, Weakly similar to T23273 hypotheti 26
446237 AW270515 Hs 149596 Homo sapienε, Similar to RIKEN cDNA 2310 26
431797 BE169641 Hs 270134 hypothetical protein FLJ20280 25
406789 AI041403 πbosomal protein L29 25
423217 NM 000094 ; Hs 1640 collagen type VII, alpha 1 (epidemiolys 25
423115 AA421973 Hs 169119 ESTs, Weakly similar to T25731 hypotheti 25
420460 AA262331 Hs 48376 Homo sapienε clone HB 2 mRNA sequence 25
436165 AI373544 Hs 331328 intermediate filament protein syncoilin 25
430542 AI557486 Hs 119122 πboεomal protein L13a 25
452827 AI571835 Hs 55468 ESTε 25
431609 AW792792 Hs 264330 N-xylsphiπgosme amidohydrolase (xid c 25
431108 AA991508 Hs 105317 ESTs 25
410310 J02931 Hs 62192 coagulation fxtor III (thromboplastm, 25
430333 S70114 Hs 239489 TIA1 cytotoxic granule assxiated RNA bi 25
439864 AI720078 Hs 291997 ESTs, Weakly similar to A47582 B-cell gr 25
438821 AA826425 Hs 192375 ESTs 25
421091 W22821 πbosomal protein L26 25
439414 NM.001183 Hs 6551 ATPase, H transporting, lysoεomal (vxuo 25
400263 Eos Control 25
451428 AW083384 Hs 11067 ESTs, Highly similar to T46395 hypotheti 25
449051 AW961400 Hs 333526 HER2 receptor tyrosine kinase (c-erb-b2 25
431615 AW295859 Hs 235860 ESTs 25
433037 NM 014158 Hε 279938 HSPC067 protein 25
409504 AA304961 Hs 699 peptidylprolyl isomerase B (cyclophil 25
409330 AK001231 Hε 53940 hypothetical protein FU 10369 25
436299 AK000767 Hs 5111 hypothetical protein FLJ20729 25
450628 AW382884 Hε 204715 ESTs 25
426793 X89887 Hs 172350 HIR (histone cell cycle regulation defx 25
431122 AI267593 Hs 250535 Homo sapienε mRNA, cDNA DKFZp434N2412 (f 25
407236 W79485 Hs 173980 nuclear matnx protein NMP200 related to 25
421109 L32832 Hs 101842 AT binding transcnption factor 1 25
408770 AW270608 Hs 170195 bone morphogenetic protein 7 (osteogenic 25
416737 AF154335 Hs 79691 LIM domain protein 25
414869 AA157291 Hs 21479 ubinuclem 1 25
431222 X56777 Hs 273790 zona pellucida glycoprotein 3A (sperm re 25
403532 NM.024638 Homo sapiens hypothetical prot 25 418649 AI096485 Hs 169341 ESTs, Moderately similar to S65657 alpha 25
443804 AL135352 Hs 255883 ESTs, Weakly similar to I38022 hypotheti 25
407887 AA579668 Hs 41072 serine (or cyεteine) proteinase inhibito 25
414556 AW975063 Hs 343443 nbosomal protein L36 25
446911 N27605 Hs 16492 DKFZP564G2022 protein 25
435126 AI393666 Hs 42315 p10-bιndιng protein 25
421866 M24470 Hs 1435 guaπosine monophosphate redudase 25
426788 U66615 Hs 172280 SWI/SNF related, matrix asεociated, acti 25
447050 NM 016314 Hε 17200 STAM like protein containing SH3 and ITA 25
408461 AB037756 Hs 45207 hypothetical protein KIAA1335 25
421594 R45689 Hs 21889 Homo εapienε cDNA FLJ12978 fis, clone NT 25
443837 AI984625 Hs 9884 spindle pole body protein 25
421867 AA481078 Hs 109045 hypothetical protein FLJ10498 25
435021 AA922192 Hs 73962 ESTs 25
435750 AB029012 Hs 4990 KIAA1089 protein 25
435025 T08990 Hs 4742 anchor attachment protein 1 (Gaa1 p, yeas 25
407255 AA012992 Hs 256301 hypothetical protein MGC13170 25
425976 C75094 Hs 334514 NG22 protein 25
449458 AI805078 Hs 208261 ESTs 25
428013 AF151020 Hs 181444 hypothetical protein 25
424369 R87622 Hs 26714 KIAA1831 protein 25
431604 AF175265 Hs 264190 vacuolar protein sorting 35 (yeast homol 25
452779 AA418775 Hε 47234 ESTs 25
433586 T85301 Hs 194397 gb yd78d06 ε1 Soares fetal liver spleen 25
438682 AA354489 Hs 222103 EBP50-PDZ interactor of 64 kD 25
427515 - T79526 Hs 179516 integral type I protein 25
418700 AI963808 Hs 86970 ESTs, Moderately similar to ALU5.HUMAN A 25
TABLE 67B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcession numbers
Pkey CAT Number Accession
415989 10194.1 BC013389 BC017398 AI023543 AA191424 AI267700 AI469633 AW958465 AW953397 AA172056 BE940298 BF909208 BF909980 BF095153
BG285837 AI720344 BF541715 M355086 AA172236
429220 15103 7 AW341473 AA448195 AW207206 AI951341 AA969259 412446 ι 63467.1 BC021735 AI669212 AL120184 AI769949 BE701002 BE184363 BE819031 BG702238 BF090049 BF963318 BF961912 BF943013 AA934514
AA151245 BF960659 AA987907 Z41449 BF908059 BF908053 BF908049 BE699424 BF908060 BF962832 BF952020 BF963134 BI035538
BF908052 BF908057 BF090026 BF943158 AI632924 BF512340 BF952021 BF960776 BF943437 BF942847 AI768015 F09778 F04816 F02721
AA102645 AI633838 AA617929 BF947001 BI035448 BE935876 AW890837 AW898604 BF957405 BF963433 BG704815
433404 7392.1 BC022980 BF224081 BG149908 AW672842 BE670687 AI702161 AW341832 BE222503 N71836 AI026061 AW953116 AW083132 AI979261
AV725377 AI423298AI640707AW675518 AI032611 AI818044 AI299508 AI911386 AI270418 BE219257 BM141826 AA826491 Z25159AA587421
N59447 Z39436 T32982 R54110 BF115783 F09044 BF808433
449625 249224.1 BI918168 AW779760 N48674 AI375997 AA235370 BG699146 AI913631 AI498402 AI016320 AA323193 R49021 D59344 BG986750 N45526
BG986917T61382 R49391 R45432 AI203107 R35004 F07491 R25094 R35360
453160 6028.5 BC009612 NM 003526 BI597616 AV761592 AV760377 AL601008 BI604131 BE645918 BG187760 BG181525 BG210634 BG192999 AI263307
AA344186 AW952966 AA033609 AA037562 AA722183 R79452 H70775 BF674991 BE769437 BG007856 AA037483 AW572535 AI143991
AA084581 AA033610 AV742510 AV735788 R08336
420218 191547.1 AW958037 R42557 AI337047 AA948360 AI638005 AA459950 AI624915 AI638047 AI467856 AI521826 M860305 AI932315 AW003092 AW271756
AW779380 AA609879 AI634791 AI493770 AI565211 Z41145 AI627952 AA303734 BE349457 AW196765 AA256527 BE089727
437124 59408.1 AL050013 BG939500 AW969191 AA769925 AI377973 AI625545 AA811365 AA521114 N24705 AI379579 AA424899 AI684671 AA829715 AI453010
N35401 AA677452 AA504340 AI209149 M883574 AI379062 AI084455 A1280147 AA644327 BF432508 N27873 N47364 N34880 AI147024 T86860
AI219716 AA960926 H25544 BI857123 AW960489 M599099 AA765246 AA328537 BG434703 M890373 M424765 AI292318 AA829886 N95742
AI218758 H25588 N36282 AA024987 N36687 BI919187 N49471 AA889970 AW166152 AA468546 AI262504 AI452782 AA554458 AA807080
AA724542 AW102730 AA909978 AW118134 AW827241 W56431 BM127381 BF436987 AI016509 AW663972 BM127686 C15552 N63435 N51744
T98800 N56980 BG108636 N49381 R49886 D61278 BI756612 AA508234 R49885 BF850422
432586 6633 1 BC022881 AU150944 BG750783 AW754175 AW857737 AI911659 AI050036 AA554053 AI826259 M568548
438869 52134.1 AF075009 R63109 R63068
450377 12109 1 AB033091 AL520743 BE811813 N53332 N99716 AL561910 AA280655 BE710392 AV705100 AW293978 AW444556M281459 AI679751 AI873695
BG700891 BI553517 R80518 BG779771 BG534451 AA479402 AW961580 BF061430 AI857643 AI768486 AW512118 AA479302 AW770384
AW072470AI041596 AI049699 AW592865 AA976261 BE879747 BG114119 AW183811 M909938 BF571621 BF350794 BF351375 BE925699
AL050294 BC010371 BF982270 AL042656 BF095732 AW812618 BF095731 BG212397 BF678765 BI038602 BG388664 AW675337 BG289398
BE939598 AW805570 AA527097 AW150540 AI693720 AA743364 AI915793 N48185 AI573107 M043474 AI351615 AI969490 AI910763 R50866
AI699181 N73808 H08164
436063 5483.1 AK000028 AA494483 AI298674 AA720773 AV761529 AI884670 AI936202 AW294235 D61652 BF881184 AV711384 N27154 AI926970 AV734970
N40094 N28596 AA884747 AA512890 BG436593 428342 6712.1 AK056315 AI015524 AA724079 BI713619 A1377728 AW293682 AI928140 AI092404 AI085630 AA731340 B 469629 AW968804 AA425658
AA769094 BF446026 AW118719 AI332765 AW500888 AW576556 AI859571 AW499664 AW614573 AW629495 AW505314 W74704 AI356361
AI923640 AW070509 AI521500 AL042095 AA609309 M761319 AI381489 H45700 AA761333 AW265424 AA909524 AA635311 AA649040
AI392620 Z40708 AI985564 AW263513 AA913892 AI693486 AW263502 AI806164 AW291137 BI061872 BI059498 AA134476 AW084888 AA036967
AW370823 T55263 BI002756 AA489664 BF827261 W74741 BF963166
424036 6226.1 NM.033445 BC001193 AI885781 BF794032 AA476620 AA810906 AA810905 AI291244 AI885097 AI359708 AI335629 H97396 AI344589 AA300377
AA457566 A 771833 BE465621 AI364068 AI364452 AI648505 AI918342 AI928670 AA886580 AL531029 AA886344 AI186419 BG329096
BM045465 AL531028 BG437151 BE868021 AA179427
450203 19009.1 AK055952 BG182168 BG220105 BG191569 BG188964 BG187388 BG220104 BG183714 BE645998 AI819354 AW974068 AI393635 AI580846
AI024796 AW020098 BI491127 AI393644 N74993 AW472959 BM478854 BI597437 H12165 BI458612 BE543192
451752 10408.5 AB032997 AI141678 AW978722 BE467119 AI761408 BF727385 AW237035 AI934521 BF436248 AI479668 Z40632 AA832081 AW295901
BF057835 BE465977 AI621269 BE465983 BF756369 N74056 AI817896 AA716567 AA934774 H62600 H09497 BF943762 BE395335 BE883333
432363 1234917.1 AW970240 AA534489 AW970323 422890 61426.1 AK057805 AW162343 AI190479 A1093318 BE048820 AI198397 AA654667 BE219303 Z39851 F02655 Z28734T16575 F10145 Z45266 AW572911
AW964436 AW004030 AI632565 BE502530 BI792383 BF056928 AA449241 AI651825 M805324 AI264863 AW196918 AA948267 AI953735
AI263703 BF056387 AW594171 AI867447 AA319159 AI903440 AW956110 AI366013 AI867923 BG911906 D81142015616 AL538697 Z25032
Z43784 R13382 AV746924 AA449369 AA318815 BF364265 H17038 H10064 F04161 T87230 R40898 AW204071 BI819428 AA683393 AA683376
Z43192T74078 T05103 F12527 T77951 H10118 H17037 BF855407 R19603
417379 1610005 1 AA196390 AA507837 AA196468
407819 7392.2 AK056626 AI800896 BF939022 BE644718 AI954754 BE218177 BE348567 AI962406 AW293122 AI968798 AI457321 BE327228 BG913531
AW939055T30280 R54166 Z43366 BG819153 BF003119 BE646274 BF940881 R18246 R42185
419733 7612.3 AK027321 W63676 W63789 BE046412 BF114614 BE646183 BM126230 AW044233 AI951970 AW663548 AI139947 AA514302 AA846232
BM126251 AA789002 AA581966 AA809643 AW188870 BE706664 BE706539 BE153177 BF084925 AL133779 AW961788 AA659693 AA347970
AA295134 AA526037 AA449282 BG190454 H61476T91396 N20018T90114 H75644 BE710736 BF687723 H28581 M249370 BF726698
BE841554 BI045099 T84625 AW129678 BG770826
432675 1237917 1 AW973834 AI791932 A1791855 AI732640 AA558833 AA559897 AI821610 447620 687223.1 AI973051 AI400921 AI796154 AW241817 AW290951 409151 4123 1 NM.004892 AF047442 BE275338 BF724863 BI917206 BE276993 AL602308 AA306105 BM152505 BC001364 AW993471 AW993481 AW993283
AW992919 AW992921 AW992980 AW992861 AW993220 BG573124 AA456385 AA234796 AI902726 AA354813 BI092644 BG778400 BI260001
BG007325 AI267455 AA426574 AI160782 AI472186 AA255500 AA434006 BG435520 AI356111 H00525 AV749060 BG944497 BG292031
AA902153 C04925 AA902160 AA383100 AW073533 AA256706 AA150809 R65766 AW958448 BE090972 BF693195 AV738979 R65855 R80136
AA484677 409960 39576.1 BE644758 AI082238 BF940027 AI201079 AI436035 AW275966 AI085394 AI291655 AW070441 AI474134 AI268978 AI769279 AI567682 AA693941
BF477668 AW664149 AA283782 BF509538 AW296868 AI268977 AI168133 BM352065 AI262769 BF941976 AI056920 AA481861 BF763697
AL565888 BM352383 AA427768 AA385346 AH 86988 AA931831 AA134972 BF217480 BF111012 AA908246 AA319849 AA318136 AL514271
BF364291 AL515057 AV702312 AA377395 AL544217 AI341000 AW193583 AI350789 AA888338 BF945380 AW879092 AA130839 T91066 N92326
AI004389 AA078832 AL572370 W04622 BE314003 AW960808 BM360872 M319160 AA130778 AL514257 433891 647290.1 AW182329 AA613792 T05304 AW858385
414922 1563.2 BG107484 AA632009 AI432670 AI656660 AI650884 AI521919 AI264653 AW150793 AW611894 AI917098 BI091245 AI651454 BF434889 AI580286
AI880735 BE301995 AI392959 AW613965 BM023628 AW515374 AI460102 BM023318 BE328188 AI952820 AI581363 AA557165 AI695677
AL562079 AI700926 AI470561 BF063058 AW196387 AU132984 BI064046 AI970157 R02122 H55924 AI521721 AA808206 AA725223 AI766003
AW339821 AA805951 AI287969 AW664827 414222 18695.1 BC021085 AL527872 AL526296 AL557087 BI255090 AU 143499 AL560356 BG823170 BE736988 AU141388 AL580262 BI764173 AU120299
AU141755 AU141988 AU142941 AU141330 AU141784 BI770885 B1911394 BE901426 BI918039 BG760842 BE883026 BI254740 BE732690
BG430761 BE792868 AW328267 AL135173 AA102674 BF726986 AL564735 BE155962 BE155979 BF741679 H67776 H59234 H89665 AW117774
AW274435 L29008 NM.003104 U07361 BF002824 BI222949 AI458045 AW951537 BF196474 AI669049 A1042523 BE463928 AU160125 AU160580
AW069877 AW015214 AI948718 BE219706 AI953605 BE217755 AI991382 AI245005 BF431179 AI521843 BE048908 AI420449 AW275385
AA336950 BE501521 BF740566 AA311404 AA384639 BI772535 BG473076 BE891298 BE246928 BM012986 BE242693 BE901342 BG746358
BF374053 AL564430 AU143835 AI635707 BF195492 AI280559 BF741685 AA385257 BE247655 W94974 BE163702 AI025167 AI827118 N78641
AL581093 AU158964 AU 158917 AI282516 AU146399 AA713947 AI285028 AA10 228 AI338522 AA832316 AI284986 AA857926 BF372568
AA570172 AI753825 AA171566 AU159257 BM194320 W93390 AW132101 AA550898 BI259678 AA522554 N55172 AW013929 AI826274 AI871237
C75260 AA934846 AA555036 AA526579 AA526466 N80270 AI538347 AW615805 AU158875 AU158883 AU159396 AI016667 AU159238 AI282517
AA406317 AI285043 N53050 AA969446 N57718 H93323 W93374 AI873751 H56011 AI936174 AA937830 AW438877 AI800550 AW328268
AI244886 AA948424 AA700604 AA832317 AA011555 H97671 M988711 AW150529 N70983 H44325 AV657614 AA902238 AA644018 AA034050
T71053 N71444 AA831158 T40892 AA706106
426991 29771.1 AK001536 AK056135 BM474813 BE887303 AK022914 AW581996 AW812945 BE882302 AA134266 BI043873 AA019433 BI862088 BM468657
AU128438 BE384458 AL353967 BI857117 BF686525 BI465223 BM460132 AU129877 BI222283 BG171592 BI043544 BG496295 BG750710
BI256542 BG108520 AU150719 AW510354 AI554256 AL353968 AA191092 BF132635
434194 62680 1 AF119847 AA437261 AA436987 AH 32965
432908 45254Ϊ.1 AF150424 AI861896 AA570057 AV738855 412652 18858 2 AI801777 BE677762 AW008210 AW009441 BE350994 BE207949 AI091475 AI802774 AI827533 AI075363 AI659979 AA687855 AI078125 AI090285
AA670058 AA602411 AA683472 AI436058 AA612826 AI038932 BG057726 A1167355 BF449023 AI289476 AW074381 BF972912 AI991780
AA889119 AI537472 Z39730 AI868953 AI192337 BE812978 BE812939 AA115248 H99006 A1915784 F08973 T16748 D20468 AA609899 BF081234
AA115336 BE812876 BE812972 BE812982 BE813006 BE813019 R43883 BE812981
437179 12239.1 AK055109 BC019085 AA187684 BG656226 BM023227 AI932311 AW264381 AA398371 BM021483 AI432433 AI375777 AI129580 AW262782
AA134107 BM023515 AA977504 AI859222 AI348454 R69725 AA975268 BM021207 AL080074 AA129218 AW207842 N90581 AA771919 AI092259
AI028416 AI074114 BG656536 BE501677 AW193419 AA917040 W90430 AI342984 AI378957 AL036486 AW020068 BI491093 BF476021 R41226
R69631 F04125 C02343 AA115589 R56480 AI400988 R54266 R31422
418166 18858.1 AK055915 BE867252 AI523348 AA765350 BF446858 Z43675 R19529 AL133837 BG389444 AW382942 BE702956 AA081961 BE835247 BE835308
BE835295 M376302 BE645790 AA375690 AA376592 AW954423 N85732 AA249770 AI754416 M213816 BF592044 AA811729 AW514842
AI633486A1096810AW183016AI635738 N27524 BE645916AI247842AW991230AI754277 H16814AI766892 BF108422AI800361 T95129
F11313 R97946 R93989 AA375242 BF109388 AI860939 AI680060 AW953899 BF971486 AI972337 AW953841 AA372437 AI216746 H11384
R38484 AA249043 AA249732
431416 120918.1 AW969151 AA532718 AA504784 AI791194 AI821930 AI821485 F37127 AA654206 F27974 447881 44623.1 AK074291 AW293424 BE676135 AI832125 BE019146 BE465019 AI761124 AA617778 AI279232 AW575897 AI672039 F28618 BF924261
AA722184 BF934174 BE004328 AV749301 BE880282 BI019798 BI019389 BF928776 AW813409 AV726604 M077560 BE272975 BF949119
AW814195 BE879126 AI697926 BF594155 BE205787 BF063513 N35828 AI948557 AI433839 AI379679 BG056182 AI589094 N23123 AA588805
AW316581 AI080272 AI421980 AI493318 BF194830 N87590 AA495993 N32996 AA699844 H96845 H96592 N28741 BI035539 BF747723
BF171066 W01350 H05495 AI243785 Z39622 AA887432 AI350659 R46102
407192 2200202 1 AA602964AA609200
434747 117643.1 AW976537 AI033582 AA837085 AA745261 AA648395 410297 2990 1 BC013939 BI494690 BI491211 AI928393 AA84354Q BG938644 AU185628 BI495842 A 173255 BM052709 AI743999 AI690144 AI922209 A1740907
AW340368 AA928759 AW118737 BF513970 AA707807 BF435295 A1339463 AI373842 AI433809 BE222392 M602308 AA428261 AI460355
AW662760 AI888087 AI342098 AA722418 W78151 N64382 BE221848 AW025901 AA452120 A1150479 AI016166 AA779515 AA661791 BM474307
BI911169 BG575154 AW953303 T33604 D59141 M385785 AA148648 BM461961 BG681168 BI602483 BE889592 AW954311 BM052986 BI962893
AI989299 Z42328 BF029504 T35668 BG402602 AU185770 AI023271 AA147719 AI434079 AI569000 AI276488 AA992453 AA342821 AA648303
AI349364 AI051008 M926941 AA350894 AW071451 N22249 AI784138 AA083847 N22258 AW440825 M661570 AA376687 AA659125 AI356299
R70463 AI383586 AA827189 BI494872 AW021094 BI494871 AA905500 AA460923 BI492041 AW028965 AI624611 BG271780 AI497723 H88862
D59858 N89979 AA658425 N81154 D62341 AI274437 N66697 H96993 AI370663 AA728850 H05232 R59374 H12223 AI935759 AI362553 D60006
N29572 AI916833 N75273 AA148710 BI597117 BG740471 AA332671 AA333874 AA643052 AW020175 R70550 BG623469 AA452342 AW965441
W19723 R32966 BE883841 R61003 AI910374 AI865262 R55325 AI468927 R34681 H96211 Z39807 BF954386
424339 50559.1 NM.015720 AF219137 AL534420 AL524055 AL537346 AL538442 BG765888 AL530054 AL525377 BG474596 BG473144 BE251553 BG706099
AL538039 BG703131 BE255806 BF805256 F12128 AL566773 BI828686 BF761480 AI204971 BG818818 BI199246 AL534816 BF529941 AA324163
AL523285 BG914330 H07952 AL534815 BE769903 AI867802 BM310135 AL533702 BE254484 BF528852 BE867462 BE740130 AL134164
AL567115 AL533701 AL524054 AL515904 AL523284 AL568203 AL534419 BF981162 BE257148 AL561833 445636 8561_5 BF339388 AI345516 BG391657 BE708967 BG026034 BE261703 H56716 H65572 H93801 T48830 R96953 R96989 R39707 BE867593 AA090310
AA090672 419175 350681 AB018322 BC012480 BI524873 AW665554 AI934469 AI479916 BF096179 BF096162 BF096132 AA744972 AI951988 AI858339 BE076331
AA886998 AI570585 AI916688 AI678811 AI693109 AI308135 AA669046 AA961064 AI018062 H80618 BE221942 R52609 AI915164 AA365626
Z44671 BI052776 BF882486 BG286184 AI589558 AA931663 AA534979 AI275392 AI273455 R52553 AA829920 H80652 AA360728 F10618
AW953666 AW176773 H85527 AA765570 AA081927 BF093262 BG743753 AL037576 AA534314 BE814964 BE973713 N49493 BE006634
BE006630 AW270037 AA234765 AI334004 BF057179 AI857450 AI341191 AI434143 AI917449 AW517207 AA255424 AW008334 AA847572
AA994211 AA861901 AA581873 AI580157 AI364363 AW242357 AW235291 N55645 AA319869 R36911 AA256551 AW044188 AI203159 N49403
F02090 AI187299 AI609644 Z40516 AW952314
441128 20932.1 BC014072 BE328850 AI356567 AI148171 AI022165 BG149661 BF000671 AA233101 AA573721 AA447991 AW016855 AI005068 AA554071
BF478215 AA906902 AW014761 BE905651 BE512923 BM047129 AA243852 M232991 AA127550 AA127551 AA570256 AI473237 BF033706
N90525 AW973623 AI359627 BG674574 BE903322
406789 0 0 AI041403 Z49148
421091 24941.2 AK057700 BC015899 BE867108 AL526926 AL527436 BG913023 AI884867 BE858461 AI885227 AI935218 BE645596 AI922406 AA778161
BF345973 AW195853 AI687121 AI336147 AI091364 AI769203 AW627859 BE677432 BF439954 BG820230 AA283686 AA812396 AI358396
AA932022 BE222881 AW016109 BM352667 BF528099 BG818616 AI935916 AA912295 BG910887 AL568301 AL567278 BI522445 BI754384
BG819375 BF835950 AA323718 AA860955 AI089847 AL520776 AL526045 AL538507 AL567798 AL536876 AL574332 BF834531 BF340116
BF835954 AL573997 AL581252 BF957667 AL580170 AW952324 AL569382 AW148695 AL559234 BG034270 BI913839 AL581327 AL565842
H43568 BF945188 AL559686 AL539326 T15481 AW895092 AL582684 BI519896
400263 18977.1 Z11692 X51466 NM.001961 M19997 BI224253 BG830478 AU122147 AU123437 BG113591 BG752624 BE886804 BI868669 BG337216 AW629935
BM016525 AI560409 AL562866 AI909178 BF849556M371735 BF038841 BF727115 BC006547 BG757526 AL555664 BI261304 BG770095
BI033486 BI517580 BG876486 BI011828 AI313235 BG831724 BF869862 BG998348 BI011834 BF888337 BF898627 BF092380 AW803215 F01241
BF805719 BG876487 AW498536 BF988866 BG998849 AA248724 BG829202 BG756456 BG032392 BI859287 BM016990 BG332369 BE933685
BE166758 BM452445 AI937808 AW026128 N23684AW006041 AI337621 F33111 BF344301 BG105450 BG387343 BF569547 BF154671
BM007368 BF569385 BE772007 BI199487 BF761700 BI261519 BF944452 BF898506 AI038390 BM044934 AW381142 BG743618 BE769206
BE893973 BI015047 BF886479 BF761350 BE769769 BG766117 BF847365 BE397834 AW371121 BF089125 BE082996 BF183193 BG180964
BF089940 BI000274 BG255503 BG674499 BG774174 BI015084
TABLE 67C
Pkey Unique number correεpondmg to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled The DNA sequence of human chromosome 22 " Dunham I et al , Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition
403047 3540153 Minuε 59793-59968
401424 8176894 Plus 24223-24428
401451 6634068 Minus 119926-121272
401747 9789672 Minus 118596-118816,119119-119244,119609-11976
404632 9796668 Plus 45096-45229
403046 3540153 Minus 55707-55859,56369-56511
404922 7341893 Plus 13248-13428
403752 7678857 Plus 33704-33828
404210 5006246 Plus 169926-170121
401519 6649315 Plus 157315-157950
401785 7249190 Minus 165776-165996,166189-166314,166408-16656
401866 8018106 Plus 73126-73623
405387 6587915 Minus 3769-3833,5708-5895
401197 9719705 Plus 176341-176452
403532 8076842 Minus 81750-81901
TABLE 68A 995 GENES UP-REGULATED IN PROSTATE CANCER COMPARED TO NORMAL ADULT TISSUES
Table 68A lists about 995 genes up-regulated in prostate cancer compared to normal adult tisεueε Theεe were εelxted from 9009 probeεetε on the Affymetπx/Eoε Hu03 GeneChip array that εhowed some expression in human xenograft tumors and cell lines The 995 genes were selxted such that the ratio of "average" prostate cancer to "average" normal adult tissues was greater than or equal to 2 5 The "average" prostate cancer level waε εet to the 85th percentile amongst prostate cancers The "average" normal adult tissue level was set to the 85th percentile amongst non-malignant tissueε In order to remove gene-spxific bxkground levels of non-spxific hybndization, the 10th percenfile value amongst non- malignant tisεues was subtrxted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eoε probeεet identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 Ratio of tumor to normal body fiεsue
Pkey ExAccn UnigenelD Unigene Title R1
448999 AF179274 Hs 22791 transmembrane protein with EGF-like and 855
426747 AA535210 Hs 171995 kallikrein 3, (prostate spxific antigen 686
446057 AI420227 Hs 149358 Trp-p8 transient rxeptor potential cati 656
400302 N48056 Hs 283946 folate hydrolase (prostate-εpxific memb 61 9
432441 AW292425 Hs 163484 ESTs 604
419526 AI821895 Hs 193481 ESTs 459
414569 AF109298 Hs 118258 prostate cancer assxiated protein 1 457
424099 AF071202 Hs 139336 ATP-bmding cassette, sub-family C (CFTR 452
432240 AI694767 Hs 129179 Homo εapiens cDNA FLJ13581 fis, clone PL 449
400298 AA032279 Hs 61635 six transmembrane epithelial antigen of 409
453370 AI470523 Hs 139336 ATP-binding cassette, sub-family C (CFTR 396 409731 AA125985 Hs 56145 thymosm beta identified in neuroblast 377
400299 X07730 Hs 171995 kallikrein 3, (prostate spxific antigen 349
400296 AA305627 Hs 139336 ATP binding cassette, sub family C (CFTR 31 7
400292 AA250737 Hs 2472 BMP-R1B 31 4
425075 M506324 Hs 1852 acid phoεphatase, prostate 31 4
409262 AK000631 Hs 52256 hypothetical protein FLJ20624 31 4
428819 AL135623 Hs 193914 KIAA0575 gene product 31 2
409361 NM 005982 Hs 54416 εme xulis homeobox (Drosophila) homolo 303
407168 R45175 Hs 117183 ESTs 296
400287 S39329 Hs 181350 kallikrein 2, prostatic 296
415539 AI733881 Hs 72472 BMP-R1B 28 8
432374 W68815 Hs 301885 Homo sapiens cDNA FLJ11346 fis, clone PL 288
433043 W57554 Hs 125019 lymphoid nuclear protein (LAF-4) mRNA 28 1
423073 BE252922 Hs 123119 MAD (mothers againεt decapentaplegic Dr 27 5
403047 NMJ05656* Homo sapiens transmembrane pr 274
444484 AK002126 Hs 11260 hypothetical protein FLJ11264 257
428336 AA503115 Hε 183752 microsemmoprotein, beta 25 0
401424 NM 001172 Homo sapienε argmaεe, type II 249
407709 AA456135 Hε 23023 ESTs 247
407122 H20276 Hs 31742 ESTs 246
425628 NM 004476 Hs 283946 folate hydrolase (prostate specific memb 232
415989 AI267700 ESTs 23 1
448290 AK002107 Hs 20843 Homo sapienε cDNA FU11245 fis, clone PL 227
437052 AA861697 Hs 120591 ESTs 226
411096 U80034 Hε 68583 mitochondnal intermediate peptidase 225
451939 U80456 Hε 27311 single minded (Drosophila) homolog 2 21 2
450096 AI682088 Hε 79375 holocarboxylase synthetase (biotin [prop 208
419743 AW408762 Hs 5957 Homo sapiens clone 24416 mRNA sequence 20 5
427958 AA418000 Hs 98280 potasεium intermediate/εmall conductance 205
431548 AI834273 Hs 9711 novel protein 19 8
434666 AF151103 Hs 112259 T cell receptor gamma locus 194
426501 AW043782 Hs 293616 ESTs 193
413597 AW302885 Hs 117183 ESTε 18 9
428862 NM 000346 Hs 2316 SRY (εex determining region Y) box 9 (ca 187
435677 AA694142 Hs 293726 ESTs, Weakly similar to TSGA RAT TESTIS 180
429220 AW207206 ESTs 17 9
408826 AF216077 Hs 48376 Homo sapiens clone HB-2 mRNA sequence 176
418961 AW967646 Hs 23023 ESTs 17 3
428898 AB033070 Hs 194408 KIAA1244 protein 173
420757 X78592 Hs 99915 androgen receptor (dihydrotestoεterone r 168
428398 AI249368 Hs 98558 ESTε 16 3
419078 M93119 Hs 89584 inεulmoma assxiated 1 158
450382 AA397658 Hs 60257 Homo sapiens cDNA FLJ13598 fis, clone PL 154
449625 NM_014253 odz (odd Oz/ten m, Drosophila) homolog 1 152
401451 NM 004496* Homo sapienε hepatocyte nucle 149
447033 AI357412 Hs 157601 ESTε 149
452594 AU076405 Hs 29981 solute camerfamily 26 (sulfate transp 147
448519 AW175665 Hs 278695 Homo sapiens prostem mRNA, complete eds 146
418829 AA516531 Hs 55999 NK homeobox (Drosophila), family 3, A 145
430376 AW292053 Hs 12532 chromosome 1 open reading frame 21 144
418848 AI820961 Hs 193465 ESTs 143
429918 AW873986 Hs 119383 ESTs 142
424012 AW368377 Hs 137569 tumor protein 63 kDa with strong homolog 14 1
418278 AI088489 Hs 83937 hypothetical protein 141
408000 L11690 Hs 198689 bullous pemphigoid antigen 1 (230/240kD) 139
443822 AI087412 Hs 143611 ESTs, Weakly similar to 2004399A cfiromos 13 3
432101 AI918950 Hs 123642 EphA3 13,3
447342 AI199268 Hs 19322 Homo sapienε, Similar to RIKEN cDNA 2010 13 1
412446 AI768015 ESTs 127
437718 AI927288 Hs 196779 ESTs 126
433404 T32982 ESTs 126
431089 BE041395 Hs 156110 ESTs, Weakly similar to unknown protein 126
427212 AW293849 Hs 58279 ESTs, Weakly similar to ALU7_HUMAN ALU S 12 5
429597 NM.003816 Hs 2442 a disintegnn and metalloproteinase doma 125
444151 AW972917 Hs 128749 alpha methylxyl-CoA rxemase 124
428046 AW812795 Hε 337534 ESTs, Moderately similar to I38022 hypot 124
453160 AI263307 H2B histone family, member L 122
433927 AI557019 Hε 116467 small nuclear protein PRAC 121
431117 AF003522 Hε 250500 delta (Drosophιla)-lιke 1 121
424800 AL035588 Hs 153203 MyoD family inhibitor 11 9
427674 NM-003528 Hs 2178 H2B histone family, member Q 11 9
424692 AA429834 Hs 151791 KIAA0092 gene product 11 7
415263 AA948033 Hs 130853 ESTs 11 3
416182 NM 004354 Hs 79069 cyclin G2 11 3
420218 AW958037 πbosomal protein L4 11 3
411887 AW182924 Hε 128790 ESTs 11 2
425154 NM 001851 Hε 154850 collagen, type IX, alpha 1 11 2
430226 BE245562 Hε 2551 adrenergic, beta-2-, receptor, surface 11 2
450325 AI935962 Hε 91973 ESTs 11 1
439444 AI277652 Hs 54578 ESTs, Weakly similar to I38022 hypotheti 11 1
440529 AW207640 Hs 16478 Homo sapiens cDNA FU21718 fis, clone C 11 0
457211 AW972565 Hs 32399 ESTs, Weakly similar to S51797 vasodilat 11 0
428600 AW863261 Hs 138860 hypothetical protein DKFZp434K1421 11 0 422728 AW937826 Hs 103262 ESTs, Weakly similar to ZN91.HUMAN ZINC 11 0
417333 AL157545 Hs 1731 9 bromodomain and PHD finger containing 3 107
434423 NM 006769 Hs 3844 LIM domain only 4 106
434170 AA626509 Hs 122329 ESTs 106
432729 AK000292 Hs 130732 hypothetical protein FLJ 20285 105
446100 AW967109 Hs 13804 hypothetical protein dJ462023 2 104
432715 AA247152 Hs 200483 ESTs Weakly similar to KIAA1074 protein 104
421896 N62293 Hs 45107 ESTs 103
401747 Homo sapiens keratin 17 (KRT17) 101
451640 AA195601 Hs 26771 Human DNA sequence from clone 747H23 on 101
431542 H63010 Hs 5740 ESTs 100
447397 BE247676 Hs 18442 E-1 enzyme 100
433285 AW975944 Hs 237396 ESTs 100
431325 AW026751 Hs 5794 ESTs Weakly similar to 2109260A B cell 99
410889 X91662 Hs 66744 twist (Drosophila) homolog (xrxephalos 98
432674 AA641092 Hs 257339 ESTs, Weakly similar to I38022 hypotheti 96
434926 BE543269 Hs 50252 mitochondnal nbosomal protein L32 96
442049 AA310393 Hs 190044 ESTs 96
443180 R15875 Hs 258576 claudin 12 95
406964 M21305 FGENES predicted novel secreted protein 95
426350 NM 003245 Hε 2022 transglutaminase 3 (E polypeptide, prote 95
456660 AA909249 Hε 112282 solute earner family 30 (zinc transport 95
448045 AJ297436 Hs 20166 prostate stem cell antigen 95
451684 AF216751 Hs 26813 CDA14 95
440594 AW445167 Hs 126036 ESTs 94
432415 T16971 Hε 289014 ESTs, Weakly similar to A43932 mucin 2 p 93
418601 AA279490 Hs 86368 calmegin 93
433332 AI367347 Hs 44898 Homo sapiens clone TCCCTA00151 mRNA sequ 92
437124 AA554458 K1AA0666 protein 92
428728 NM 016625 Hs 191381 hypothetical protein 92
438869 AF075009 gb Homo sapiens full length insert cDNA 9 1
431992 NM 002742 Hs 2891 protein kinase C, mu 89
413992 W26276 Hs 136075 RNA, U2 small nuclear 89
428342 AI739168 Homo sapienε cDNA FU 13458 fiε, clone PL 89
418836 AI655499 Hε 161712 ESTs 88
409799 D11928 Hε 76845 phosphosenne phosphatase-like 88
400294 N95796 Hε 278695 Homo sapiens prostem mRNA, complete eds 87
434826 AF155661 Hs 22265 pyruvate dehydrogenase phosphatase 87
418250 U29926 Hs 83918 adenosine monophosphate deammaεe (isofo 87
425905 AB032959 Hs 318584 novel C3HC4 type Zinc finger (nng finge 87
418329 AW247430 Hs 84152 cystathioπme beta synthase 87
450203 AF097994 L-kynureπine/alpha-aminoadipate ammotra 87
425465 L18964 Hs 1904 protein kinase C iota 85
416239 AL038450 Hs 48948 ESTs 85
436962 AW377314 Hs 5364 DKFZP5641052 protein 84
450164 AI239923 Hs 63931 ESTs 84
452744 AI267652 Hs 246107 Homo sapiens mRNA, cDNA DKFZp434E082 (fr 84
440774 AI420611 Hs 153934 ESTs 83
444922 AI921750 Hs 144871 Homo sapiens cDNA FLJ13752 fis, clone PL 83
410870 U81599 Hs 66731 homx box B13 83
435047 AA454985 Hs 54973 cadhenn like protein VR20 82
418564 AA631143 Hs 278695 Homo sapienε prostem mRNA, complete eds 82
451027 AW519204 Hs 40808 ESTs 82
445873 AA250970 Hs 251946 poly(A) binding protein, cytoplasmic 1-1 82
423349 AF010258 Hs 127428 homx box A9 81
421928 AF013758 Hs 109643 polyadenylate binding protein interactin 8 1
432586 AA568548 ESTs 80
426108 AA622037 Hs 166468 programmed cell death 5 80
417153 X57010 Hs 81343 collagen, type II, alpha 1 (pπmary oste 80
416653 AA768553 Hs 193145 metallothionein 1E (functional) 79
447476 BE293466 Hs 20880 ESTs, Weakly similar to I38022 hypotheti 79
450377 AB033091 KIAA1265 protein 78
429769 NM 004917 Hs 218366 kallikrein 4 (prostase, enamel matnx, p 77
416815 U41514 Hs 80120 UDP-N xetyl alpha-D-galxtosamine polyp 77
433323 AA805132 Hs 159142 ESTs 77
451952 AL120173 Hs 301663 ESTs 77
452367 U71207 Hs 29279 eyes absent (Drosophila) homolog 2 77
421470 R27496 Hs 1378 annexm A3 77
420092 AA814043 Hs 88045 ESTs 76
416111 AA033813 Hs 79018 chromatin assembly factor 1 , subunit A ( 76
440749 W22335 Hs 7392 hypothetical protein MGC3199 76
441866 BE464341 Hs 21201 nxtin 3, DKFZP566B0846 protein 76
411019 AW993097 Hs 48617 Homo εapiens cDNA FLJ12540 fis, clone NT 75
421566 NM 000399 Hs 1395 early growth responεe 2 (Krox-20 (Drosop 74
451418 BE387790 Hs 26369 hypothetical protein FLJ20287 74
433517 AW022133 Hs 189838 ESTs 74
415621 AI648602 Hs 55468 ESTs 74
442592 BE566623 Hs 29899 ESTε, Weakly similar to G02075 transcπp 73
452340 NM 002202 Hs 505 ISL1 transcnption factor, LIM/homeodoma 73
450244 AA007534 Hs 125062 ESTs 72
433293 AF007835 Hs 32417 hypothetical protein MGC4309 72
425259 AL049280 Hs 155397 Homo sapiens mRNA cDNA DKFZp564K143 (fr 72
434485 AI623511 Hs 118567 ESTs 72 442772 AW503680 Hs 5957 Homo sapiens clone 24416 mRNA sequence 71
425211 M18667 Hs 1867 progastπcsin (pepsiπogen C) 71
431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (plxenta 70
408418 AW963897 Hs 44743 KIAA1435 protein 70
436063 AK000028 nbosomal protein S24 70
412350 AI659306 Hs 73826 protein tyrosine phosphatase, non rxept 69
414664 AA587775 Hs 66295 multi PDZ-domain-contaiπiπg protein 69
428465 AW970976 Hs 293653 ESTs 69
436476 AA326108 Hs 33829 bHLH protem DEC2 68
431585 BE242803 Hs 262823 hypothetical protein FLJ 10326 68
434808 AF155108 Hs 256150 Homo sapiens, Similar to RIKEN cDNA 2810 67
432103 T15803 Hs 272458 protein phosphatase 3 (formeriy 2B), cat 67
456088 BE177320 Hs 156148 hypothetical protein FLJ13231 66
429084 AJ001443 Hs 195614 splicing factor 3b, subunit 3, 130kD 66
422486 BE514492 Hs 117487 gene near HD on 4p163 with homology to 66
410227 AB009284 Hs 61152 exostoses (multιpte)-lιke 2 66
453439 AI572438 Hs 32976 guanine nucleotide binding protein 4 65
410037 AB020725 Hs 58009 KIAA0918 protein 65
420297 AI628272 Hs 88323 ESTε, Weakly similar to ALU1 HUMAN ALU S 64
409648 AW451449 Hs 57749 ESTs 64
448148 NM 016578 Hs 20509 HBV pX associated protein 8 64
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of 64
422134 AW179019 Hs 112110 mitochondnal ribosomal protein L42 63
415068 Z19448 Hs 131887 ESTs, Weakly similar to T24396 hypotheti 63
404632 NM.022490 Homo sapienε hypothetical prot 63
412935 BE267045 Hs 75064 tubulm-specific chaperone c 63
453308 AW959731 Hs 323099 ESTs 63
449048 Z45051 Hs 22920 similarto S68401 (cattle) glucose indue 63
410762 AF226053 Hs 66170 HSKM B protein 63
436032 AA150797 Hs 109276 latex protein 63
456508 AA502764 Hs 123469 ESTs, Weakly similar to AF208855 1 BM-01 63
413328 Y15723 Hs 75295 guanylate cyclase 1, soluble, alpha 3 62
425071 NM 013989 Hs 154424 deiodmase, lodothyromne, type II 62
424036 AA770688 H2A histone family, member L 62
418245 AA088767 Hs 83883 transmembrane, prostate androgen induced 62
450861 AI523898 Hs 17617 ESTs 61
418821 AA436002 Hs 183161 ESTs 61
458809 AW972512 Hs 20985 sιπ3-assocιated polypeptide, 30kD 6 1
432527 AW975028 Hs 102754 ESTε 61
433730 AK002135 Hs 3542 hypothetical protein FU11273 61
449845 AW971183 Hs 6019 DnaJ (Hεp40) homolog, εubfamily C, membe 6 1
420948 AB016898 Hs 100469 myeloid/lymphoid or mixed-lineage leukem 61
425704 U79293 Hs 159264 Human clone 23948 mRNA εequeπce 60
458440 AI095468 Hs 135254 Homo sapiens clone 1 thrombospondm mRNA 60
419647 AA348947 Hs 91816 hypothetical protein 60
455497 AA112573 Hs 278695 Homo sapiens prostem mRNA, complete eds 60
428593 AW207440 Hs 185973 degenerative spermatxyte (homolog Droεo 59
400303 AA242758 Hs 79136 UV-1 protein, eεtrogen regulated 59
446416 AV658299 Hs 163959 ESTε 59
407819 R42185 ESTε 59
430387 AW372884 Hε 240770 nuelearcap binding protein εubumt 2, 2 59
410102 AW248508 Hε 279727 ESTε, homologue of PEM-3 [Ciona savignyi 59
429165 AW009886 Hε 118258 prostate cancer assxiated protein 1 59
417873 BE266659 Hε 293659 Homo sapiens, Similar to RIKEN cDNA A430 58
410240 AL157424 Hε 61289 syπaptojanin 2 58
421305 BE397354 Hs 324830 diptheπa toxin reεistaπce protein requi 58
451406 AI694320 Hs 6295 ESTs, Weakly similar to T17248 hypotheti 58
416795 AI497778 Hs 20509 HBV pX assxiated proteιn-8 57
427701 AA411101 Hs 243886 nuclear autoantigenio sperm protein (his 57
451468 AW503398 Hs 293663 ESTs, Moderately similar to I38022 hypot 57
433852 AI378329 Hs 126629 ESTs 57
432882 NM 013257 Hs 279696 serum/glucocorticoid regulated kinase-li 56
419440 AB020689 Hs 90419 KIAA0882 protein 56
435706 W31254 Hs 7045 GL004 protein 56
431583 AL042613 Hs 262476 S-adeπosylmethionme dxarboxylase 1 56
442409 BE208843 Hs 129544 hypothetical protein MGC15438 56
453171 R76472 Hs 65646 ESTε 56
437252 AI433833 Hs 164159 ESTε, Weakly similar to ALULHUMAN ALU S 56
422083 NM 001141 Hs 111256 arachidonate 15-lιpoxygenase, sxond typ 56
429638 AI916662 Hs 211577 kinectin 1 (kinesm rxeptor) 55
403046 NM.005656* Homo εapienε tranεmembrane pr 55
447805 AW627932 Hs 302421 gemιn4 55
443162 T49951 Hs 9029 DKFZP434G032 protein 54
418555 AI417215 Hs 87159 hypothetical protein FLJ12577 54
437162 AW005505 Hs 5464 thyroid hormone rxeptor coadivating pr 54
419465 AW500239 Hs 21187 Homo εapienε cDNA FLJ23068 fis, clone L 54
440146 AW014231 Hs 90790 Homo sapiens cDNA FLJ22930 fis, clone K 54
427308 D26067 Hs 174905 KIAA0033 protein 54
409151 AA306105 SEC22, vesicle trafficking protein (S c 54
432840 AK001403 Hs 279521 hypothetical protein FLJ20530 54
423242 AL039402 Hs 125783 DEME-6 protein 53
453082 H18835 Hs 31608 hypothetical protein FLJ20041 53
441021 AW578716 Hs 7644 H1 histone family, member 2 53 415276 U88666 Hs 78353 SFRS protein kinase 2 53
400290 H18836 Hs 31608 hypothetical protein FLJ20041 53
432435 BE218886 Hs 282070 ESTs 53
417318 AW953937 Hs 240845 ESTs 53
429467 NM 004477 Hs 203772 FSHD region gene 1 53
416276 U41060 Hs 79136 UV-1 protein, estrogen regulated 53
410076 T05387 Hs 7991 ESTs 53
420039 NM 004605 Hs 94581 εulfolransferase family cytosolic, 2B, 52
423445 NM 014324 Hs 128749 alpha ethylacyl CoA racemase 52
436420 AA443966 Hs 31595 ESTs 52
414085 AA114016 Hs 75746 aldehyde dehydrogenase 1 family, member 5 1
422048 NM 012445 Hs 288126 spondm 2, extracellular matnx protein 51
427176 AW381569 Hs 40334 ESTε 5 1
450832 AW970602 Hs 105421 ESTs 51
448807 AI571940 Hs 7549 ESTs 5 1
420568 F09247 Hs 247735 protxadherin alpha 10 51
421685 AF189723 Hs 106778 ATPase Ca Iransporting, type 2C member 50
427615 BE410107 Hs 179817 CGI 82 protein, PSDR1 50
430598 AK001764 Hs 247112 hypothetical protein FLJ10902 50
452576 AB023177 Hs 29900 KIAA0960 protein 50
431724 AA514535 Hs 283704 ESTs 50
409757 NM 001898 Hs 123114 cystatm SN 50
432242 AW022715 Hs 162160 ESTs, Weakly similar to ALU4.HUMAN ALU S 50
407103 AA424881 Hs 256301 hypothetical protein MGC13170 50
421154 AA284333 Hs 287631 Homo sapiens cDNA FU14269 fis, clone PL 50
400301 X03635 Hs 1657 estrogen receptor 1 50
426006 R49031 Hε 22627 ESTs 50
452679 Z42387 Hε 83883 transmembrane, prostate androgen induced 49
446880 AI811807 Hε 108646 Homo sapiens cDNA FU14934 fis, clone PL 49
444108 R55784 Hs 140942 ESTs 49
452259 AA317439 Hs 28707 signal εequence receptor, gamma (translo 49
419083 A1479560 Hs 98613 Homo εapienε cDNA FLJ 12292 fis, clone MA 49
416854 H40164 Hs 80296 Purkmje cell protein 4 49
422890 Z43784 ankyπn 3, node of Ranvier (ankyπn G) 49
428330 L22524 Hs 2256 matrix metalloproteinase 7 (matπlysm, 49
419168 AI336132 Hε 33718 Homo εapienε cDNA FLJ 12641 fiε, clone NT 49
452017 AF109302 Hs 27495 proεtate cancer assxiated protein 7 49
456362 AW973003 Hs 179909 hypothetical protein FLJ22995 49
442501 AA315267 Hs 23128 ESTs 48
439735 A1635386 Hs 142846 hypothetical protein 48
451752 AB032997 KIAA1171 protein 48
423583 AL122055 Hs 129836 KIAA1028 protein 48
446157 BE270828 Hs 131740 Homo sapiens cDNA FLJ22562 fis, clone H 48
432363 AA534489 gb nf76g11 s1 NCI CGAP_Co3 Homo sapiens 48
433313 W20128 Hs 296039 ESTs 48
408101 AW968504 Hs 123073 CDC2-related protein kmase 7 48
453857 AL080235 Hs 35861 DKFZP586E1621 protein 48
451982 F13036 Hs 27373 Homo sapiens mRNA cDNA DKFZp56401763 (f 47
447574 AF162666 Hs 18895 tousled-like kinase 1 47
429299 AI620463 Hs 347408 hypothetical protein MGC13102 47
420522 AW957137 Hs 98541 hypothetical protein 47
417379 AA196390 gb zp99b10 s1 Stratagene muscle 937209 H 47
411031 W37943 Hs 34892 KIAA1323 protein 47
431725 X65724 Hε 2839 Nome diseaεe (pseudoglioma) 47
441224 AU076964 Hε 7753 calumenin 47
407813 AL120247 Hs 40109 KIAA0872 protein 47
440074 AA863045 Hs 10669 ESTs, Weakly similar to T00050 hypotheti 47
430294 AI538226 Hs 32976 guanine nucleotide binding protein 4 47
415082 AA160000 Hs 137396 ESTs, Weakly similar to JC5238 galaotosy 47
414922 D00723 glycine cleavage system protein H (am o 47
430945 U80669 Hs 55999 NK homeobox (Drosophila), family 3, A 47
438825 BE327427 Hs 79953 ESTs 47
425174 D87450 Hs 154978 KIAA0261 protein 47
420380 AA640891 Hs 102406 ESTs 47
410193 AJ132592 Hs 59757 zinc finger protein 281 47
440300 N39760 Hs 8859 Homo εapiens, Similar to RIKEN cDNA 5830 46
436761 AI817776 Hs 236557 ESTs 46
410275 U85658 Hs 61796 tranεcπption fxtor AP-2 gamma (xfivat 46
404922 NM 003071 Homo sapiens SWI/SNF related, 46
436556 AI364997 Hs 7572 ESTs 46
429302 AU076674 Hs 198899 eukaryotic translation initiation factor 46
447595 AW379130 Hs 18953 phoεphodieεterase 9A 46
433006 BE242758 Hs 190223 ESTs, Moderately similar to T29285 hypot 45
407894 AJ278313 Hs 41143 phosphoinositide spxific phospholipaεe 45
418818 AA228899 Hs 101307 Homo sapiens HUT11 protein mRNA, partial 45
433556 W56321 Hs 111460 calcium/calmodulin dependent protein km 45
443123 AA094538 Hs 272808 putative transcnption regulation nuclea 45
419991 AJ000098 Hs 94210 eyes absent (Drosophila) homolog 1 45
419594 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 45
453390 AA862496 Hs 28482 ESTs 45
417061 AI675944 Hs 188691 Homo sapiens cDNA FLJ12033 fis, clone HE 45
419239 AA468183 Hs 184598 Homo sapienε cDNA FU23241 fis, clone C 45
436873 N23874 Hs 50477 RAB27A, member RAS oncogene family 45 408001 AA046458 Hs.95296 ESTs 4.4
413950 AA249096 Hε.32793 ESTs 4.4
416655 AW968613 Hε.79428 BCL2/adenovirus E1B 19kD-interxting pro 4.4
418004 U37519 Hε.87539 aldehyde dehydrogenase 3 family, member 4.4
419733 AW362955 Homo sapiens cDNA FLJ14415 fis, clone HE 4.4
433233 AB040927 Hε.301804 KIAA1494 protein 4.4
439979 AW600291 Hε.6823 hypothetical protein FU 10430 4.4
430589 AJ002744 Hε.246315 UDP-N-xetyl-alpha-D-galactosamine:polyp 4.4
417958 AA767382 Hs.193417 ESTs 4.4
450680 AF131784 Hs.25318 Homo sapienε clone 25194 mRNA εequence 4.4
435020 AW505076 Hs.301855 DiGeorge syndrome critical region gene 8 4.4
437396 BE140396 Hs.21621 hypothetical protein DKFZp762O076 4.4
425810 AI923627 Hs.31903 ESTs 4.4
426028 NM.001110 Hs.172028 a disintegnn and metalloproteinase doma 4.3
452747 BE153855 Hs.61460 Ig superfamily receptor LNIR 4.3
429259 AA420450 Hs.292911 Plakophilin 4.3
452092 BE245374 Hs.27842 hypothetical protein FU11210 4.3
437967 BE277414 Hs.5947 mel transforming oncogene (derived from 4.3
459284 AF155660 Hs.300496 mitochondria! solute carrier 4.3
417067 AJ001417 Hε.81086 solute carrier family 22 (extraneuronal 4.3
423453 AW450737 Hs.128791 CGI-09 protein 4.3
407137 T97307 gb:ye53h05.s1 Soares fetal liver spleen 4.3
448826 AI580252 Hs.293246 ESTs, Weakly similar to putative p150 [H 4.3
419713 AW968058 Hs.92381 nudix (nucleoside diphosphate linked moi 4.3
427359 AW020782 Hs.79881 Homo εapienε cDNA: FU23006 fiε, clone L 4.3
450402 BE218027 Hε.89969 ESTε 4.3
428055 AA420564 Hε.101760 ESTε 4.3
429441 AJ224172 Hs.204096 lipophilin B (uteroglobin family member) 4.3
432675 AI791855 ESTs 4.2
439963 AW247529 Hs.6793 platelet-activating fxtor xetylhydrola 4.2
445707 AI248720 Hs.114390 ESTs 4.2
410297 AA148710 lumican 4.2
416737 AF154335 Hs.79691 LIM domain protein 4.2
430255 AK000703 Hε.323822 Homo sapiens mRNA for KIAA1551 protein, 4.2
421829 AB018330 Hs.108708 calcium/calmodulin-dependent protein kin 4.2
447620 AW290951 ESTs 4.2
426647 AA243464 Hs.294101 pre-B-cell leukemia transcription fxtor 4.2
432886 BE159028 Hs.279704 chromatin accessibility complex 1 4.2
446237 AW270515 Hs.149596 Homo sapieπε, Similar to RIKEN cDNA 2310 4.2
421878 AA299652 Hs.111496 Homo εapienε cDNA FU11643 fiε, clone HE 4.2
423337 NM.004655 Hs.127337 axin 2 (conductiπ, axil) 4.2
435854 AJ278120 Hs.4996 putative ankyrin-repeat containing prote 4.2
427723 AI355260 Hs.279789 histone dexetylase 3 4.2
430122 NM.013342 Hs.233765 TCF3 (E2A) fusion partner (in childhood 4.2
416140 AI918035 Hε.301198 roundabout (axon guidance rxeptor, Dros 4.2
428231 U17989 Hs.183105 nuclear autoantigen 4.2
447966 AA340605 Hε.105887 ESTε, Weakly similar to Homolog of rat Z 4.1
432274 AK000382 Hs.274251 hypothetical protein FU20375; KIAA1797 4.1
432621 AI298501 Hs.21192 ESTs, Weakly similar to T46428 hypotheti 4.1
408063 BE086548 Hε.42346 calcineurin-binding protein calsarcin-1 4.1
407192 AA609200 gb:af12e02.s1 Soareε.teεtiε.NHT Homo sap 4.1
426716 NM 006379 Hε.171921 sema domain, immunoglobulin domain (Ig), 4.1
427479 BE410092 Hs.178471 KIAA0798 gene product 4.1
434194 AF119847 Homo sapienε PRO1550 mRNA, partial eds 4.1
422072 AB018255 Hs.111138 KIAA0712 gene product 4.1
411145 BE439553 Hs.250528 Homo sapfens, clone IMAGE:4098694, mRNA, 4.1
449459 BE546846 Hs.195048 ESTs 4.1
421662 NM 014141 Hs.106552 cell recognition molxule Caspr2 4.1
445309 AL157474 Hs.12504 likely ortholog of mouse Arkadia 4.1
412520 AA442324 Hs.795 H2A histone family, member O 4.0
448663 BE614599 hypothetical protein MGC14797 4.0
425689 W16480 Hs.24283 ESTs, Moderately similar to reduced expr 4.0
433647 AA603367 Hs.222294 ESTs 4.0
426030 BE243933 Hs.108642 zinc finger protein 22 (KOX 15) 4.0
418838 AW385224 Hs.35198 xtonucl∞tide pyrophosphatase/phosphodi 4.0
439820 AL360204 Hs.283853 Homo sapiens mRNA full length insert cDN 4.0
422634 NM.016010 Hs.118821 CGI-62 protein 4.0
453469 AB014533 Hs.33010 KIM0633 protein 4.0
418827 BE327311 Hε.47166 HT021 4.0
446791 AI632278 Hs.195922 ESTs 4.0
443884 N20617 Hs.194397 leptin rxeptor 4.0
416857 AA188775 Hε.292453 ESTs 4.0
401519 C15000476*:gi|12737279|reflXP_012163.1| 4.0
407846 AA426202 Hε.40403 Cbp/p300-interxfing tranεxfivator, wit 4.0
431689 AA305688 Hs.267695 UDP-Gal:betaGlcNAc beta 1,3-galxtoεyltr 3.9
408784 AW971350 Hs.63386 ESTε 3.9
435655 AW105663 Hs.6947 HSPC069 protein 3.9
432615 AA557191 Hs.55028 ESTε, Weakly εimilar to 154374 gene NF2 3.9
448804 AW512213 Hε.342849 ADP-riboεylation fxtor-like 5 3.9
430389 AL117429 Hε.240845 DKFZP434D146 protein 3.9
432278 AL137506 Hε.274256 hypothetical protein FU23563 3.9
414869 AA157291 Hs.21479 ubinuclein 1 3.9
429163 AA884766 gb:am20a10.s1 Soares.NFLT_GBC.S1 Homo s 3.9 444190 AI878918 Hs 10526 cyεteine and glycine πch protein 2 39
443991 NM 002250 Hs 10082 potassium intermediate/small conductance 39
433339 AF019226 Hs 8036 glioblaεtoma overexpreεεed 39
435021 AA922192 Hs 73962 ESTs 39
412834 R77123 Hs 79881 Homo sapiens cDNA FLJ23006 fis, clone L 39
442607 AA507576 Hs 288361 Homo sapienε cDNA FLJ22696 fiε, clone H 39
408833 AW612232 Hs 254835 ESTs 39
432952 M813887 Hε 188173 Homo sapienε cDNA FU12187 fis, clone MA 39
456177 NM 012391 Hs 79414 prostate epithelium εpecific Ets transcr 38
433345 AI681545 Hs 152982 hypothetical protein FU13117 38
421887 AW161450 Hs 109201 CGI-86 protein 38
434614 AI249502 Hs 29669 ESTs 38
425910 AA830797 Hs 184760 CCAAT-box-bindmg transcnption fxtor 38
432370 AA308334 Hs 274424 N acetylneuraminic xid phosphate syntha 38
413010 M393273 Hs 75133 transcnption fxtor 6-lιke 1 (mitochond 38
435114 AA775483 Hs 288936 mitxhondπal πbosomal protein L9 38
439024 R96696 Hs 35598 ESTs 38
426991 AK001536 Homo sapienε cDNA FU10674 fiε, clone NT 38
427871 AW992405 Hε 59622 Homo εapienε, clone IMAGE 3507281, mRNA, 38
439671 AW162840 Hs 6641 kinesm family member 5C 38
418113 AI272141 Hs 83484 SRY (sex determining region Y) box 4 38
422424 AI186431 Hs 296638 prostate differentiation fxtor 38
447439 AA313565 Hs 145020 ESTs, Weakly similar to KIAA1205 protein 38
414178 AW957372 Hs 46791 ESTs, Weakly similar to I38022 hypotheti 38
427099 AB032953 Hs 173560 odd Oz ten m homolog 2 (Drosophila, mous 38
407908 BE379758 Hs 110853 uncharxteπzed hematopoietic stem/proge 38
440695 AW088363 Hs 246240 ESTs 38
429686 AI871613 Hs 28538 Homo sapiens cDNA FU21086 fis, clone C 38
447533 NM 004786 Hs 18792 thioredoxin like 32kD 38
411190 AA306342 Hs 69171 protein kinaεe C-fike 2 38
426126 AL118747 Hs 26691 ESTs 38
434263 N34895 Hs 44648 ESTs 38
414407 AA147026 Hε 76704 ESTs 37
432426 AW973152 Hε 31050 ESTs 37
425770 NM 014363 Hs 159492 spaεtic ataxia of Charlevoix Saguenay (s 37
432579 AF043244 Hs 278439 nucleolar protein 3 (apoptosis represεor 37
444101 R19175 Hs 169793 πboεomal protein L32 37
432908 AI861896 ESTε 37
432800 BE391046 Hs 278962 AIM-1 protein 37
429966 BE081342 Hs 283037 HSPC039 protein 37
419972 AL041465 Hs 182982 golgm 67 37
410001 AB041036 Hs 57771 kallikrein 11 37
432205 AI806583 Hs 125291 ESTε 37
401197 ENSP00000229263ΗSPC213 37
420061 AW024937 Hs 29410 ESTε 37
431103 M57399 Hs 44 pleiotrophin (hepaπn binding growth fx 37
433577 AW007080 Hs 284192 ESTs 37
435017 AA336522 Hs 12854 angiotensin II, type I receptor-aεsxiat 37
420805 L10333 Hs 99947 reticulon 1 37
401866 Target Exon 37
457183 H91882 Hs 118569 Dvl binding protein IDAX (inhibition of 37
427982 NM.016156 Hs 181326 KIAA1073 protein 37
405387 NM.022170* Homo sapiens Williams Beuren 37
449933 AW157098 Hs 324104 Human DNA sequence from clone RP1-63M2 o 37
432388 X15218 Hs 2969 v-ski avian εarcoma viral oncogene homol 37
438157 AW137011 Hs 49576 ESTε 37
451945 BE504O55 Hs 211420 ESTs 37
452721 AJ269529 Hs 301871 solute earner family 37 (glycerol-3-pho 36
454229 AW957744 Hs 278469 Ixπmal proline πch prote 36
416974 AF010233 Hs 80667 RALBP1 assxiated Eps domain containing 36
421537 BE383488 Hs 105547 neural proliferation, differentiation an 36
428738 NM 000380 Hs 192803 xeroderma pigmentosum, complementation g 36
440494 BE618768 Hs 7232 acetyl Coenzyme A carboxylase alpha 36
407748 AL079409 Hs 38176 KIAA0606 protein, SCN Orcadian Oscillat 36
453049 BE537217 Hs 30343 ESTs 36
422089 M523172 Hs 103135 ESTs, Weakly similar to SFR4.HUMAN SPLIC 36
408096 BE250162 Hs 83765 dihydrofolate redudase 36
407204 R41933 Hs 140237 ESTs, Weakly similar to ALULHUMAN ALU S 36
450649 NM 001429 Hs 25272 E1A binding protein p300 36
436489 AJ272269 Hs 121429 zinc-binding protein Rbcc728 36
447818 W79940 Hs 21906 Homo εapienε clone 24670 mRNA εequence 36
424285 BE207168 Hs 144630 nuclear rxeptor εubfamily 2, group F, m 36
452260 AA453208 Hs 330994 RAB9, member RAS oncogene family 36
420344 BE463721 Hs 97101 putative G protein-coupled rxeptor 36
427715 BE245274 Hs 180428 KIAA1181 protein 36
426793 X89887 Hs 172350 HIR (histone cell cycle regulation defx 36
419879 Z17805 Hs 93564 Homer, neuronal immediate early gene, 2 36
403752 NMJ02753* Homo sapienε mitogen xtivate 36
418559 AA225048 Hs 104207 ESTε 36
438523 H66220 Hs 278177 ESTs 36
438705 AI049624 Hs 283390 ESTs, Weakly similar to 2109260A B cell 36
443960 AI093577 Hs 255416 hypothetical protein FLJ21986 35
412513 AA322599 Hε 5163 ESTs, Weakly similar to AF151840 1 CGI 8 35 428695 AI355647 Hε 189999 puπnergic rxeptor (family A group 5) 35
419517 AF052107 Hε 90797 Homo sapiens clone 23620 mRNA sequence 35
446494 AA463276 Hs 288906 WW Domain-Containing Gene 35
417515 L24203 Hs 82237 ataxia-telaπgiedasia group D assxiated 35
433891 AA613792 gb no97h03 s1 NCI CGAP_Pr2 Homo εapienε 35
427315 AA179949 Hs 175563 Homo εapienε mRNA cDNA DKFZp564N0763 (f 35
445525 BE149866 Hε 14831 Homo sapiens, Similar to zinc finger pro 35
434672 AW294020 Hε 117721 ESTs 35
453288 AW583292 Hε 274412 similar to yeast Upf3, vaπant A 35
434970 AW272262 Hε 225767 ESTs 35
417193 AI922189 Hs 288390 hypothetical protein FU22795 35
437617 AI026701 Hs 5716 KIM0310 gene product 35
445943 AW898533 Hs 181574 ESTs 35
412628 AI972402 Hε 306051 hypothetical protein MGC2648 35
452167 N75238 Hε 13075 Homo sapienε cDNA FU23013 fiε, clone L 35
410467 AF102546 Hs 63931 dxhεhund (Drosophila) homolog 35
440193 AW902312 Hs 7037 Homo sapiens clone 24923 mRNA sequence 35
451815 AW974911 Hs 184793 Homo sapienε cDNA FLJ21880 fis clone H 35
429170 NM 001394 Hs 2359 dual spxificity phosphatase 4 35
410082 AA081594 Hs 158311 Musaεhi (Drosophila) homolog 1 35
436087 BE300296 Hs 5054 CGI-133 protein 35
437898 W81260 Hs 43410 ESTs 35
451131 AI267586 Hs 268012 fatty acid Coenzyme A ligase, long-chain 35
439609 AW971945 Hs 293236 ESTs 35
443555 N71710 Hs 21398 ESTs, Moderately similar to A Cham A, H 35
418610 AW245993 Hs 223394 hypothetical protein MGC2742 35
409960 BE261944 hexokmase 1 35
425263 NM.001197 Hs 155419 BCL2-ιnterxtmg killer (apoptosis indue 35
404210 NM 005936 Homo sapiens myeloid/lymphoid 35
442323 AW016669 Hs 29190 ESTs 35
452707 AI093823 Hs 45070 ESTε 35
421437 AW821252 Hs 104336 hypothetical protein 35
426514 BE616633 Hs 170195 bone morphogenetic protein 7 (osteogenic 34
450628 AW382884 Hs 204715 ESTs 34
446825 BE266822 Hs 344097 filamm A, alpha (xtin binding protein- 34
421867 AA481078 Hs 109045 hypothetical protein FU10498 34
434954 AF161455 Hs 284295 Homo sapienε HSPC337 mRNA, partial eds 34
452908 AB001451 Hs 30965 neuronal She adaptor homolog 34
429922 Z97630 Hs 226117 H1 histone family, member 0 34
448734 BE614070 Hs 326416 Homo εapieπs mRNA, cDNA DKFZp564H1916 (f 34
434293 NM 004445 Hs 3796 EphB6 34
414222 AL135173 sorbitol dehydrogenase 34
421674 T10707 Hs 296355 hypothetical protein FU23138 34
438279 AA805166 Hs 154762 HIV-1 rev binding protein 2 34
411078 AI222020 Hs 182364 CxoaCπsp 34
419749 X73608 Hs 93029 sparc/oεteonxfin, cwcv and kazal like d 34
432302 M345857 Hs 274307 KIAA1442 protein 34
407944 R34008 Hs 239727 desmocollm 2 34
431674 AA098901 Hs 301642 G-protein coupled rxeptor 34
408291 AB023191 Hs 44131 KIM0974 protein 34
431578 AB037759 Hs 261587 GCN2 elF2alpha kinase 34
440789 AB007857 Hs 7416 KIAA0397 gene product 34
434958 T99949 Hs 303428 Homo sapiens cDNA FU14832 fis, clone OV 34
452295 BE379936 Hs 28866 programmed cell death 10 34
417229 AA975096 Hs 19522 hypothetical protein PR02849 34
439593 BE073597 Hs 124863 ESTs 34
407136 T64896 Hs 287420 Homo sapiens cDNA FU11533 fis, clone HE 34
421044 AF061871 Hs 101302 Human DNA sequence from clone RP1-238D15 34
427461 AA531527 Hs 332040 hypothetical protein MGC13010 33
417315 AI080042 Hs 180450 πbosomal protein S24 33
423392 AA195037 Hs 169341 HTPAP protein 33
412652 AI801777 ESTs 33
415172 AF079529 Hs 78106 phosphodiesterase 8B 33
418372 AA311833 Hs 84318 replication protein A1 (70kD) 33
447958 AW796524 Hε 68644 Homo sapiens microsomal signal peptidase 33
425010 T16837 Hε 4241 ESTs 33
420460 AA262331 Hε 48376 Homo sapiens clone HB-2 mRNA sequence 33
443181 AI039201 Hs 283316 ESTs 33
442064 AI422867 Hs 88594 ESTs 33
431663 NM_016569 Hs 267182 TBX3-ιso protein 33
412926 AI879076 Hs 75061 mxrophage myπstoylated alanme-πch C 33
420818 AW969635 Hs 33032 ESTs, Weakly similar to 1207289A reverεe 33
408829 NM 06042 Hs 48384 heparan εulfate (glucoεamine) 3-O-sulfot 33
408681 AW953853 Hs 292833 ESTs, Weakly similar to I38022 hypotheti 33
436278 BE396290 Hs 5097 synaptogyπn 2 33
424560 M158727 Hs 150555 protein predicted by clone 23733 33
417215 BE253181 Hs 81687 non metaεtatic cells 3, protein expreεse 33
418166 AI754416 Cdc42 effector protein 3 33
434629 AA789081 Hs 4029 glioma-amplified εequence-41 32
427398 AW390020 Hs 20415 chromoεome 21 open reading frame 11 32
457489 AI693815 Hε 127179 cryptic gene 32
434747 AA837085 ESTε 32
413125 BE244589 Hε 75207 glyoxalaεe I 32 435561 AA351978 Hs.4943 hepatxellular carcinoma assxiated prot 3.2
447210 AF035269 Hs.17752 phosphatidylεerine-εpxific phospholipas 3.2
422522 AI023428 Hε.34549 ESTs, Highly similar to S94541 1 clone 4 3.2
423396 AI382555 Hs.127950 bromodomain-containing 1 3.2
401785 NM_002275*:Homo εapieπε keratin 15 (KRT1 3.2
441345 AW068579 Hs.7780 Homo εapienε mRNA; cDNA DKFZp564A072 (fr 3.2
451404 M460775 Hε.6295 ESTε, Weakly similar to T17248 hypotheti 3.2
422173 BE385828 Hs.250619 phorbolin-like protein MDS019 3.2
452099 BE612992 Hs.27931 hypothetical protein FLJ 10607 similar to 3.2
452826 BE245286 Hs.301636 peroxisomal biogenesiε fxtor 6 3.2
419829 AI924228 Hs.115185 ESTε, Moderately εimilar to PC4259 ferri 3.2
407688 W25317 Hs.37616 Human D9 εplice vaπant B mRNA, complete 3.2
406214 NM.016371:Homo sapiens hydroxysteroid (1 3.2
416292 AA179233 Hε.42390 nasopharyngeal carcinoma susceptibility 3.2
438714 AA814859 Hs.160074 ESTs 3.2
433213 AW665130 Hs.137190 ESTs 3.2
412170 D16532 Hs.73729 very low density lipoprotein rxeptor 3.2
409340 BE174629 Hs.321130 hypothetical protein MGC2771 3.2
413142 M81740 Hs.75212 omithine dxarboxylase 1 3.2
451338 AW612322 Hε.19131 transcription fxtor Dp-2 (E2F dimerizat 3.2
437179 AA393508 εerologically defined colon cancer antig 3.2
418700 AI963808 Hε.86970 ESTs, Moderately similar to ALU5.HUMAN A 3.2
438361 M805666 Hs.146217 Homo sapiens cDNA: FU23077 fis, clone L 3.2
450546 AA010200 Hs.175551 ESTε 3.2
409995 AW960597 Hs.129206 ESTε 3.2
408739 W01556 Hε.44685 ESTs, Moderately similar to I38022 hypot 3.2
438821 M826425 Hs.192375 ESTs 3.2
403532 NM_024638:Homo sapiens hypothetical prot 3.2
452941 AL110347 Hs.31074 N-sulfoglucosamine sulfohydrolase (sulfa 3.1
414341 D80004 Hs.75909 KIAA0182 protein 3.1
423044 AA320829 Hs.97266 protocadherin 18 3.1
429716 R25685 Hs.211933 collagen, type XIII, alpha 1 3.1
444367 H54892 Hs.10974 hypothetical protein FLJ22390 3.1
423551 AA327598 Hε.89633 ESTε 3.1
453186 AK001708 Hε.32271 hypothetical protein FU10846 3.1
413550 W03011 Hε.306881 MSTP043 protein 3.1
431933 AI187057 Hs.132554 ESTε 3.1
439778 AL109729 Hs.99364 putative tranεmembrane protein 3.1
448044 AI458682 gb:tk13e01.x1 NCI_CGAP_Lu24 Homo sapiens 3.1
422017 NM 003877 Hε.110776 STAT induced STAT iπhibitor-2 3.1
421254 AK001724 Hε.102950 ∞at protein gamma-cop 3.1
424339 BE257148 endoglycaπ 3.1
445109 AF039916 Hε.12330 xtonucleoside triphosphate diphosphohyd 3.1
425320 U29344 Hε.83190 fatty xid synthase 3.1
426170 BE161065 Hs.167531 methylcrotonoyl-Coenzyme A carboxylase 2 3.1
408770 AW270608 Hs.170195 bone morphogenetic protein 7 (oεteogenic 3.1
442202 BE272862 Hs.106534 hypothetical protein FU22625 3.1
417622 AW298163 Hs.82318 WAS protein family, member 3 3.1
439864 AI720078 Hε.291997 ESTε, Weakly εimilar to A47582 B-cell gr 3.1
433036 M574091 Hε.105964 ESTs 3.1
447050 NM 016314 Hs.17200 STAM-like protein containing SH3 and ITA 3.1
436299 AK000767 Hs.5111 hypothetical protein FU20729 3.1
408380 AF123050 Hε.44532 diubiquitin 3.1
407910 M650274 Hs.41296 fibroπ∞tin leucine rich transmembrane p 3.1
445098 AL050272 Hs.12305 DKFZP566B183 protein 3.1
431797 BE169641 Hs.270134 hypothetical protein FU20280 3.1
437296 AA350994 Hε.20281 KIM1700 3.1
452627 AI122843 Hs.184319 ESTs, Weakly similar to KIAA1006 protein 3.1
448913 AA194422 Hs.22564 myosin VI 3.1
415079 R43179 Hε.22895 hypothetical protein FLJ23548 3.0
408157 AA047685 Hs.62946 ESTs 3.0
443337 Y07604 Hs.9235 non-metastalic cells 4, protein expreεse 3.0
410310 J02931 Hε.62192 coagulation fxtor III (thromboplastin, 3.0
437546 AW074836 Hs.173984 T-box 1 3.0
451134 AA318315 Hs.25999 hypothetical protein FU22195 3.0
423932 T95633 Hs.189703 ESTs 3.0
433495 AW373784 Hs.71 alpha-2-glycoprotein 1, zinc 3.0
453293 AA382267 Hs.10653 ESTs 3.0
428171 AA489323 Hs.182825 ribosomal protein L35 3.0
428293 BE250944 Hs.183556 εolute camerfamily 1 (neutral amino a 3.0
426657 NM 015865 Hs.171731 εolute carrier family 14 (urea tranεport 3.0
406627 T64904 Hs.163780 ESTs 3.0
418259 AA215404 ESTs 3.0
426110 NM.002913 Hε.166563 replication fxtor C (xtivator 1) 1 (14 3.0
411089 AA456454 cell division cycle 2-like 1 (PITSLRE pr 3.0
431416 AA532718 ESTs 3.0
431631 M548906 Hε.122244 ESTs 3.0
409251 R10723 Hs.20573 ESTs 3.0
434974 AA778711 eukaryotic translation initiation fxtor 3.0
447147 AA910353 Hs.75432 ESTs, Weakly similar to T23482 hypotheti 3.0
450937 R49131 Hs.26267 ATP-dependant interferon response protei 3.0
432728 NM 006979 Hs.278721 HLA clasε II region expressed gene KE4 3.0
433037 NM 014158 Hε.279938 HSPC067 protein 3.0 411598 BE336654 Hs.70937 H3 histone family, member A 3.0
430268 AK000737 Hs.237480 hypothetical protein FU20730 3.0
443725 AW245680 Hs.9701 growth arrest and DNA-damage-inducible, 3.0
431155 AW971213 gb:EST383301 MAGE resequences, MAGL Homo 3.0
407355 AA846203 Hs.193974 ESTs, Weaklyεimilarto ALULHUMAN ALU S 3.0
438209 AL120659 Hs.6111 aryl-hydrocarboπ receptor nuclear transi 3.0
434392 AW983709 Hs.250824 Homo sapiens cDNA: FLJ23435 fis, clone H 3.0
432810 AA863400 Hε.23054 ESTs 3.0
430333 S70114 Hε.239489 TIA1 cytotoxic granule-assxiated RNA-bi 3.0
445596 R89543 Hs.12942 veεicle trafficking protein 3.0
406670 W79632 Hs.256301 hypothetical protein MGC13170 3.0
452779 AA418775 Hs.47234 ESTε 3.0
439680 AW245741 Hs.58461 ESTε, Weakly similar to A35659 krueppel- 3.0
408298 AI745325 Hs.271923 Homo sapienε cDNA: FU22785 fiε, clone K 3.0
424395 AA165082 Hs.146388 microtubule-aεsxiated protein 7 2.9
423472 AF041260 Hs.129057 breast carcinoma amplified sequence 1 2.9
425920 AL049977 Hs.162209 claudin 8 2.9
409927 T69981 gb:yc19d03.r1 Stratagene lung (937210) H 2.9
447881 BE620886 GCN1 (general control of amiπo-acid synt 2.9
439584 AA838114 Hs.221612 ESTs 2.9
417601 NM 014735 Hs.82292 KIAA0215 gene product 2.9
452268 NM 003512 Hs.28777 H2A histone family, member L 2.9
422576 BE548555 Hε.118554 CGI-83 protein 2.9
438510 ALO80220 Hs.6285 DKFZP586P0123 protein 2.9
423217 NM 000094 Hs.1640 collagen, type VII, alpha 1 (epidermolys 2.9
427581 NM 014788 Hε.179703 KIAA0129 gene product 2.9
447963 AI452973 Hε.165900 ESTε, Weakly εimilar to ALULHUMAN ALU S 2.9
443015 R33261 Hε.6614 ESTs, Weakly similar to A43932 mucin 2 p 2.9
429351 AK001490 Hs.200016 hypothetical protein FU10628 2.9
425294 AF033827 Hs.155553 HNK-1 sulfotransferase 2.9
452955 AW390282 Hs.31130 transmembrane 7 superfamily member 2 2.9
416439 AA180363 Hs.118769 ESTs 2.9
442315 AA173992 Hs.7956 ESTs, Moderately similar to ZN9LHUMAN Z 2.9
446911 N27605 Hs.16492 DKFZP564G2022 protein 2.9
428801 AW277121 Hs.254881 ESTs 2.9
430462 AI584156 Hs.105640 Homo sapienε, clone IMAGE:4139775, mRNA, 2.9
420552 AK000492 Hε.98806 hypothetical protein 2.9
428180 AI129767 Hε.182874 guanine nucleotide binding protein (G pr 2.9
418222 AI675881 Hε.86538 ESTs 2.9
433009 AA761668 gb:nz24c08.s1 NCI.CGAP.GCB1 Homo sapiens 2.9
432140 AK000404 Hε.272688 hypothetical protein FLJ20397 2.9
434517 AA635690 Hε.337251 hypothetical protein MGC2487 2.9
448718 AA220235 Hε.153959 hypothetical protein MGC15436 2.9
408196 AL034548 Hε.43627 SRY (sex determining region Y)-box 22 2.9
419849 BE041436 Hs.93379 eukaryotic translation initiation fxtor 2.9
452256 AK000933 Hs.28661 Homo sapiens cDNA FU 10071 fis, clone HE 2.9
430375 AW371048 Hs.93758 H4 histone family, member H 2.9
409650 T08490 Hs.288969 HSCARG protein 2.9
413588 AA971014 Hε.75432 IMP (inosine monophoεphate) dehydrogenas, 2.9
412719 AW016610 ESTs 2.9
438552 AJ245820 Hε.6314 type I transmembrane rxeptor (seizure-r 2.9
439621 AI200281 Hs.123910 ESTε, Highly similar to B34087 hypotheti 2.9
437050 AA766420 ESTs 2.9
414256 AW410035 Hs.75862 MAD (mothers against dxapentaplegic, Dr 2.9
429343 AK000785 Hε.199480 Homo sapiens, Similar to epsin 3, clone 2.9
416941 BE000150 Hs.48778 niban protein 2.9
421594 R45689 Hs.21889 Homo εapieπε cDNA FU12978 fiε, clone NT 2.9
436213 AA325512 Hε.71472 hypothetical protein FU10774; KIAA1709 2.9
436823 AW749865 ESTε, Weakly similar to I38022 hypotheti 2.8
441266 H15968 Hε.293845 Homo εapienε, clone IMAGE:3502329, mRNA, 2.8
426761 AI015709 Hε.172089 Homo εapiens mRNA; cDNA DKFZp586l2022 (f 2.8
413746 AA133243 Hε.171553 ESTs, Moderately similarto CLC3_HUMAN C 2.8
457733 AW974812 ESTs 2.8
400860 Target Exon 2.8
436165 AI373544 Hs.331328 intermediate filament protein syncoilin 2.8
433312 AI241331 Hs.131765 ESTs, Moderately similar to I38937 DNA/R 2.8
431604 AF175265 Hε.264190 vxuolar protein sorting 35 (yeast homol 2.8
421717 AF230924 Hs.107187 divalent cation tolerant protein CUTA 2.8
453912 AL121031 SWI/SNF related, matrix assxiated, xfi 2.8
435703 AW630133 Hs.83313 GK003 protein 2.8
431108 AA991508 Hs.105317 ESTs 2.8
451040 AA324743 Hε.40808 ESTs 2.8
443837 AI984625 Hε.9884 spindle pole body protein 2.8
418196 AI745649 Hs.26549 KIAA1708 protein 2.8
450447 AF212223 Hs.25010 hypothetical protein P15-2 2.8
409330 AK001231 Hε.53940 hypothetical protein FU10369 2.8
413762 AW411479 Hs.848 FK506-binding protein 4 (59kD) 2.8
433586 T85301 Hs.194397 gb:yd78d06.s1 Soareε fetal liver εpleen 2.8
424720 M89907 Hs.152292 SWI/SNF related, matrix aεεxiated, xfi 2.8
422027 AL043100 Hs.306319 fatty xid amide hydrolase 2.8
422717 AI557623 Hε.119475 cold inducible RNA-biπding protein 2.8
412843 AF007555 Hs.74624 protein tyrosine phosphatase, rxeptor t 2.8
434237 AF119908 Hs.235516 hypothetical protein PR02955 2.8 407255 AA012992 Hs 256301 hypothetical protein MGC13170 28
431472 AK001023 Hs 256549 nucleotide binding protein 2 (E coli M 28
423318 AW467064 Hs 5740 ESTs 28
454144 BE280478 Hs 182695 hypothetical protein MGC3243 28
452827 AI571835 Hs 55468 ESTs 28
452040 AW973242 Hε 293690 ESTs, Weakly similar to I38022 hypotheti 28
418830 BE513731 Hs 88959 hypothetical protein MGC4816 28
417517 AF001176 Hs 82238 POP4 (proceεsing of prxurεor , S cerev 28
419286 AA236005 Hs 128764 ESTs 28
430287 AW182459 Hs 125759 ESTs, Weakly similar to LEU5.HUMAN LEUKE 28
420911 U77413 Hs 100293 O-linked N-xetylglucoεamme (GlcNAc) tr 28
428054 AI948688 Hs 266619 ESTε 28
409504 AA304961 Hs 699 pepfidylprolyl isomerase B (cyclophilm 28
440080 AW051597 ESTε 28
431609 AW792792 Hε 264330 N xylsphmgosine amidohydrolaεe (xid c 28
447896 AI436124 Hs 294069 Homo εapienε CDNA FU13384 fiε clone PL 28
431525 AA506656 Hs 6185 KIAA1557 protein 28
442995 AA532511 Hε 288455 Homo sapiens cDNA FU23270 fis, clone C 28
433101 AW572317 Hs 12082 Homo sapienε mRNA, cDNA DKFZp566L203 (fr 28
449052 AW029507 Hs 161102 ESTs 28
418663 AK001100 Hs 41690 desmxollm 3 28
442013 AA506476 Hs 10600 Human DNA εequence from clone RP11 353C1 28
449051 AW961400 Hs 333526 HER2 rxeptor tyrosine kinase (c-erb-b2, 28
453038 AW292415 Hs 20509 HBV pX assxiated proteιπ-8 28
419175 AW270037 KIAA0779 protein 28
426788 U66615 Hs 172280 SWI/SNF related, matnx aεsxiated, xti 28
421091 W22821 πbosomal protein L26 28
413435 X51405 Hs 75360 carboxypeptidase E 28
432651 AW973744 Hs 293100 ESTε 28
452700 AI859390 Hs 288940 five span transmembrane protein M83 28
454148 AW732837 Hs 42390 nasopharyngeal carcinoma εuscepfibility 28
419452 U33635 Hs 90572 PTK7 protein tyrosine kinase 7 28
425491 AA883316 Hs 255221 ESTs 28
414556 AW975063 Hs 343443 πbosomal protein L36 28
435126 AI393666 Hs 42315 p10-bιndmg protein 28
435602 AF217515 Hs 283532 uncharxteπzed bone marrow protein BM03 27
441128 AA570256 ESTε, Weakly similar to T23273 hypotheti 27
440340 AW895503 Hs 125276 ESTs 27
410339 AI916499 Hs 298258 ESTs 27
430542 AI557486 Hs 119122 πbosomal protein L13a 27
406789 AI041403 πbosomal protein L29 27
424130 AL050136 Hs 140945 Homo sapiens mRNA, cDNA DKFZp586L141 (fr 27
449518 BE395253 Hs 30861 ESTε 27
410099 AA081630 KIAA0036 gene product 27
422000 M30599 Hs 110637 homx box A10 27
407110 AA018042 Hs 252085 Prader-Willi/Angelman εyndrome-5 27
415443 T07353 Hs 7948 ESTε 27
432745 AI821926 gb nt78f05 x5 NCI.CGAP.Pr3 Homo εapienε 27
409299 AA045650 Hε 53125 small nuclear πbonucleoprotein D2 polyp 27
424369 R87622 Hs 26714 KIAA1831 protein 27
417831 H16423 Hs 82685 CD47 antigen (Rh related antigen, iπtegr 27
424723 BE409813 Hs 152337 protein argmme N ethyltransferaεe 3(h 27
451428 AW083384 Hs 11067 ESTs, Highly similar to T46395 hypotheti 27
400263 Eos Control 27
435750 AB029012 Hs 4990 KIAA1089 protein 27
443804 AL135352 Hs 255883 ESTs, Weakly similar to I38022 hypotheti 27
421709 AA159394 Hs 107056 CED-6 protein 27
421077 AK000061 Hs 101590 hypothetical protein 27
416359 AL042210 Hs 16493 hypothetical protein DKFZp762N2316, KIM 2.7
442104 L20971 Hs 188 phosphodiesterase 4B, cAMP-spxific (dun 27
411605 AW006831 ESTε 27
437133 AB018319 Hs 5460 KIM0776 protein 27
407236 W79485 Hs 173980 nuclear matnx protein NMP200 related to 27
432125 AW972667 Hs 183006 Homo sapiens cDNA FU12300 fis, clone MA 27
427657 AV652249 Hs 180107 polymerase (DNAdirxted), beta 27
445636 AW105401 πbosomal protein L29 27
443801 AW206942 Hs 253594 intron of tπchorhinophalangeal syndro 27
420223 N27807 πbosomal protein L4 27
427515 T79526 Hs 179516 integral type I protein 27
447673 AI823987 Hs 182285 ESTs 27
411960 R77776 Hs 18103 ESTs 27
433212 BE218049 Hs 121820 ESTs 27
448244 BE613416 Hs 336425 Homo sapiens, clone MGC 17296, mRNA, com 27
441551 AA318224 Hs 296141 ESTs 27
421883 X55079 Hs 1437 glucosidase, alpha, xid (Pompe diεease, 27
411562 AL050201 Hs 70769 hypothetical protein DKFZp586E1923 27
434851 AA806164 Hs 116502 ESTs 27
442875 BE623003 Hs 23625 Homo sapiens clone TCCCTA00142 mRNA sequ 27
421109 L32832 Hs 101842 AT-binding transcnption fxtor 1 27
432450 AI990739 Hs 158184 ORF 27
426174 AA547959 Hs 115838 ESTs 27
445919 T53519 Hs 334692 hypothetical protein MGC14141 27
423115 AA421973 Hs 169119 ESTs, Weakly similar to T25731 hypotheti 27 431222 X56777 Hs 273790 zona pellucida glycoprotein 3A (sperm re 27
451558 NM 001089 Hs 26630 ATP-bmding casεette, εub-family A (ABC1 27
431615 AW295859 Hs 235860 ESTε 27
418649 AI096485 Hs 169341 ESTε, Moderately similar to S65657 alpha 27
431122 AI267593 Hs 250535 Homo sapienε mRNA, cDNA DKFZp434N2412 (f 27
438682 M354489 Hs 222103 EBP50-PDZ interactor of 64 kD 27
424954 NM 000546 Hs 1846 tumor protein p53 (Li-Fraumeni εyndrome) 27
458082 AW978811 Hs 314451 ESTε, Weakly similar to ALULHUMAN ALU S 27
427087 BE073913 Hs 173515 uncharacteπzed hypothalamus protein HT0 27
412524 M417813 Hs 44208 hypothetical protein FLJ23153 27
435176 M744875 Hs 189413 ESTs 27
419390 AI701162 Hs 90207 hypothetical protein MGC11138 27
428013 AF151020 Hs 181444 hypothetical protein 27
441094 U33819 Hs 7647 MYCassxiated zinc finger protein (pun 27
451356 M748418 Hs 164577 ESTs 27
408461 AB037756 Hs 45207 hypothetical protein KIM1335 27
418516 NM.006218 Hs 85701 phosphoιπosιtιde-3-kιnaεe, catalytic, al 27
423476 AL035633 Human DNA εequence from clone RP5-1046G1 27
444034 AL161957 Hs 10177 plxkεtπn homology domain interxting p 27
404913 NM.024408* Homo εapiens Notch (Drosophil 27
407378 M299264 Hε 57776 ESTs, Moderately similar to I38022 hypot 27
441054 M913591 ESTε 26
428500 AI815395 Hs 184641 fatty acid deεaturase 2 26
430512 AF182294 Hs 241578 U6 snRNA-asεxiated Sm-like protein LSm8 26
433301 AW296280 Hs 152016 Homo εapienε cDNA FU22140 fiε, clone H 26
444381 BE387335 Hs 283713 ESTε, Weakly similar to S64054 hypotheti 26
443666 AI458179 Hε 41528 ESTs, Weakly similar to neuronal thread 26
427378 BE515037 Hε 177556 melanoma antigen, family D, 1 26
439414 NM.001183 Hε 6551 ATPase, H transporting, iysoεomal (vxuo 26
421866 M24470 Hε 1435 guanoεine moπophoεphate redudase 26
421605 BE440108 Hε 106127 RNA polymerase 1 16 kDa subunit 26
426797 AW936258 Hε 342849 ADP-πbosylation fxtor-like 5 26
410935 BE067395 Hs 66881 dynein, cytoplasmic, intermediate polype 26
407887 M579668 Hs 41072 seπne (or cysteine) proteinaεe inhibito 26
430341 NM 006348 Hs 239631 golgi transport complex 1 (90 kDa subuni 26
424956 AW198103 Hs 18724 ESTε, Weakly similar to granule cell mar 26
452748 AB011128 Hs 30512 Homo sapiens mRNA for KIM0556 protein, 26
408212 M297567 Hs 43728 hypothetical protein 26
407893 BE408359 Hs 43621 Homo sapiens, Similar to hypothetical pr 26
425976 C75094 Hs 334514 NG22 protein 26
448424 AW009892 Hs 31924 ESTs 26
420164 AW339037 Hs 24908 ESTs 26
443444 AW952619 Hs 17235 Homo sapiens clone TCCCIA00176 mRNA sequ 26
412774 M120865 Hs 23136 ESTs 26
445922 AI337316 Hs 147998 ESTs 26
429925 NM 000786 cytxhrome P450, 51 (laπosterol 14-alpha 26
419222 AD001528 Hs 89718 εpermine εynthase 26
417327 NM 004922 Hs 81964 SEC24 (S cerevisiae) related gene famil 26
420337 AW295840 Hs 14555 Homo sapienε cDNA FU21513 fiε, clone C 26
408743 AL110246 Hs 47367 KIAA1785 protein 26
434011 AW953437 Hs 5486 clone FLB5214 26
434976 AI963821 ESTε 26
417454 NM 000202 Hs 172458 iduronate 2-εulfatase (Hunter syndrome) 26
448789 BE539108 Hs 22051 hypothetical protein MGC15548 26
441049 W88920 Hs 29341 hypothetical protein FU22376 26
437271 AL137445 Hs 28846 Homo sapieπε mRNA, cDNA DKFZp5660134 (fr 26
425017 AL119305 Hs 26409 ESTs 26
440333 AI378424 Hs 288761 hypothetical protein FU21749 26
434551 BE387162 Hs 280858 ESTs, Highly similar to A35661 DNA excis 26
413132 NM 006823 Hs 75209 protein kinase (cAMP-dependent, catalyfj 26
409619 AK001015 Hs 55220 BCL2-assxιated athanogene 2 26
444550 BE250716 Hs 87614 ESTs 26
446258 AI283476 Hs 263478 ESTs 26
440191 AI990417 tubulin, beta 5 26
453187 AI161383 Hs 34549 ESTs, Highly similar to S94541 1 clone 4 26
412133 U83460 Hs 73614 εolute earner family 31 (copper transpo 26
426841 A1052358 Hs 193726 ESTs 26
435937 M830893 Hs 119769 ESTs 26
425960 AW410646 Hs 164649 hypothetical protein DKFZp434H247 26
456161 BE264645 Hs 282093 hypothetical protein FU21918 26
456236 AF045229 Hs 82280 regulator of G-protein signalling 10 26
435025 T08990 Hs 4742 anchor attachment protein 1 (Gaalp, yeas 26
416751 T48130 Hs 5897 Homo sapiens mRNA, cDNA DKFZp586P1622 (f 26
458946 M009716 Hs 42311 ESTs 26
424762 AL119442 Hs 183684 eukaryotic translation initiation fxtor 26
449458 AI805078 Hs 208261 ESTs 26
432409 M806538 Hs 130732 KIM1575 protein 26
425184 BE278288 Hs 155048 Lutheran blood group (Auberger b antigen 26
442336 AW340958 Hs 7572 ESTs 26
445622 AF106697 Hs 12971 thioredoxm redudase beta 26
440409 AW294316 ESTs 26
444610 AI174783 gb HA2501 Human fetal liver cDNA library 26
425863 U43604 Hs 159901 Human unidentified mRNA, partial εequenc 26 436972 AA284679 Hs 25640 claudin 3 26
426809 BE313114 Hs 29706 ESTs 26
431183 NM 006855 Hs 250696 KDEL (Lys-Asp-Glu Leu) endoplasmic retic 26
457638 AI792670 Hs 144405 ESTε 26
442821 BE391929 Hs 8752 transmembrane protein 4 25
435522 N64214 Hs 9774 syπovial sarcoma traπslxatioπ gene on c 25
406764 M429825 Hs 343443 πboεomal protein L36 25
422032 M476966 Hs 110857 polymerase (RNA) III (DNA directed) poly 25
409125 R17268 Hs 343567 axoπal transport of synaptic veεicles 25
416801 X98834 Hs 79971 sal (Drosophila) like 2 25
446091 AW022192 ESTs 25
419848 M251242 Hs 103238 ESTs 25
415015 NM 002109 Hs 77798 histidyl tRNAεynthetaεe 25
431836 AF178532 Hs 271411 beta-site APP-cleaving enzyme 2 25
414987 M524394 Hs 294022 hypothetical protein FLJ14950 25
447087 AW403870 Hs 301872 hypothetical protein MGC4840 25
456050 R79445 Hs 76230 nbosomal protein S10 25
426178 M371409 Hs 105664 hypothetical protein FU22294 25
414528 M148950 Hs 188836 ESTs 25
426494 AL119528 Hs 170098 KIAA0372 gene product 25
407656 AW747986 Hs 37443 Homo sapieπε mRNA, cDNA DKFZp434B2119 (f 25
437330 AL353944 Hs 50115 Homo εapienε mRNA cDNA DKFZp761 J1112 (f 25
449139 BE268315 Hs 23111 phenylalanine tRNA εynthetase like 25
448153 Y10805 Hs 20521 HMT1 (hnRNP methyltransferase, S cerevi 25
417386 AL037228 Hε 82043 D123 gene product 25
409420 Z15008 Hs 54451 laminin, gamma 2 (nicein (100kD), kalmi 25
408796 M688292 Hs 170345 ESTs 25
407627 AI419020 Hs 62620 chromosome 6 open reading frame 1 25
421535 AB002359 Hs 105478 phosphoπbosylformylglycinamidme εyntha 25
415862 R51034 Hs 144513 ESTε 25
426418 M90464 Hs 169825 collagen type IV, alpha 5 (Atport syndr 25
436557 W15573 Hs 5027 ESTε, Weakly similar to A47582 B-cell gr 25
413517 N76712 Hs 44829 ESTs, Weakly similar to I38022 hypotheti 25
449500 AW956345 Hs 12926 ESTs 25
457090 AL080243 Hs 180920 nboεomal protein S9 25
445389 NM 016831 Hs 12592 peπod (Drosophila) homolog 3 25
410006 AW732308 Hs 57783 eukaryotic translation initiation fxtor 25
452906 BE207039 Hs 306123 MAGEF1 protein 25
450341 N90956 Hs 17230 hypothetical protein FU22087 25
419430 AI878942 Hs 90336 ATPaεe, H tranεportmg, lyεoεomal (vxuo 25
440099 AL080058 Hs 6909 DKFZP564G202 protein 25
452518 AA280722 Hs 24758 ESTε, Weakly εimilar to I38022 hypotheti 25
431843 M516420 ESTε, Weakly similarto I38022 hypotheti 25
424795 AW102850 Hs 153177 πbosomal protein S28 25
448019 AW947164 Hε 195641 ESTs, Moderately similar to I38022 hypot 25
450704 H85157 Hs 40696 ESTs 25
400262 Eos Control 25
435266 AK001942 Hs 4863 hypothetical protein DKFZp566A1524 25
418039 R06859 Hs 193172 ESTs, Weakly similarto 138022 hypotheti 25
429491 NM.012111 Hs 204041 chromosome 14 open reading frame 3 25
456844 AI264155 Hs 152981 CDP-dixylglycerol εynthase (phosphatida 25
413781 J05272 Hs 850 IMP (inoεme monophoεphate) dehydrogenas 25
437450 AL390154 Hε 26954 Homo sapienε mRNA, cDNA DKFZp762G123 (fr 25
424005 AB033041 Hs 137507 vang (van gogh, Drosophila) like 2 25
429332 AF030403 Hs 199263 Ste-20 related kinaεe 25
438572 BE267017 Hs 6315 xetylεerotonm O-methyltraπεferase-like 25
425692 D90041 Hs 155956 N-xetyltransferase 1 (arylamine N ∞ety 25
431188 W05656 Hs 169755 ESTs 25
408803 AF248953 Hs 24049 golgi autoantigen, golgin subfamily a, 2 25
414482 S57498 Hs 76252 endothelin rxeptor type A 25
437762 T78028 Hs 154679 εynaptotagmm I 25
425722 AI659076 Hs 97031 hypothetical protein MGC13047 25
433681 AI004377 Hs 200360 Homo εapienε cDNA FU13027 fis, clone NT 25
451585 AK001171 Hs 326422 hypothetical protein MGC4549 25
424959 NM 005781 Hs 153937 xfrvated p21cdc42Hs kinase 25
407151 H25836 Hs 301527 ESTs, Moderately similar to unknown [H s 25
446054 AB014537 Hs 13604 KIAA0637 gene product 25
452556 H78517 Hs 33905 ESTε 25
421026 AL047332 Hs 101067 GCN5 (general control of ammo-xid εynt 25
407687 AK002011 Hs 37558 hypothetical protein FU11149 25
433683 AI817723 Hs 22678 hypothetical protein FU21832 25
TABLE 68B
Pkey Unique Eoε probeset identifier number
CAT number Gene cluster number Accession Genbank aαeεsion numberε
Pkey CAT Number Acceεεion 415989 10194 1 BC013389 BC017398 AI023543 AA191424 A1267700 AI469633 AW958465 AW953397 AA172056 BE940298 BF909208 BF909980 BF095153
BG285837 AI720344 BF541715 AA355086 AA172236
429220 15103_7 AW341473 AA448195 AW207206 AI951341 AA969259 449625 249224.1 BI918168 AW779760 N48674 AI375997 AA235370 BG699146 AI913631 AI498402 AI016320 AA323193 R49021 D59344 BG986750 N45526
BG986917T61382 R49391 R45432 AI203107 R35004 F07491 R25094 R35360
412446 63467.1 BC021735 AI669212 AL120184 AI769949 BE701002 BE184363 BE819031 BG702238 BF090049 BF963318 BF961912 BF943013 AA934514
AA151245 BF960659 AA987907 Z41449 BF908059 BF908053 BF908049 BE699424 BF908060 BF962832 BF952020 BF963134 BI035538
BF908052 BF908057 BF090026 BF943158 AI632924 BF512340 BF952021 BF960776 BF943437 BF942847 AI768015 F09778 F04816 F02721
AA102645 AI633838 AA617929 BF947001 BI035448 BE935876 AW890837 AW898604 BF957405 BF963433 BG704815
433404 7392.1 BC022980 BF224081 BG149908 AW672842 BE670687 AI702161 AW341832 BE222503 N71836 AI026061 AW953116 AW083132 AI979261
AV725377 AI423298 A1640707 AW675518 AI032611 AI818044 AI299508 AI911386 AI270418 BE219257 BM141826 AA826491 Z25159 AA587421
N59447 Z39436 T32982 R54110 BF115783 F09044 BF808433
453160 6028.5 BC009612 NM.003526 BI597616 AV761592 AV760377 AL601008 BI604131 BE645918 BG187760 BG181525 BG210634 BG192999 AI263307
AA344186 AW952966 AA033609 AA037562 AA722183 R79452 H70775 BF674991 BE769437 BG007856 AA037483 AW572535 AI143991
AA084581 AA033610 AV742510 AV735788 R08336
420218 191547.1 AW958037 R42557 AI337047 AA948360 AI638005 AA459950 AI624915 AI638047 AI467856 AI521826 AA860305 AI932315 AW003092 AW271756
AW779380 AA609879 AI634791 AI493770 AI565211 Z41145 AI627952 AA303734 BE349457 AW196765 AA256527 BE089727
437124 59408.1 AL050013 BG939500 AW969191 AA769925 AI377973 AI625545 AA811365 AA521114 N24705 AI379579 AA424899 AI684671 AA829715 AI453010
N35401 AA677452 AA504340 AI209149 AA883574 AI379062 AI084455 AI280147 AA644327 BF432508 N27873 N47364 N34880 AI147024T86860
AI219716 AA960926 H25544 BI857123 AW960489 AA599099 AA765246 AA328537 BG434703 AA890373 AA424765 AI292318 AA829886 N95742
AI218758 H25588 N36282 AA024987 N36687 BI919187 N49471 AA889970 AW166152 AA468546 AI262504 AI452782 AA554458 AA807080
AA724542 AW102730 AA909978 AW118134 AW827241 W56431 BM127381 BF436987 AI016509 AW663972 BM127686 C15552 N63435 N51744
T98800 N56980 BG108636 N49381 R49886 D61278 BI756612 AA508234 R49885 BF850422
438869 52134.1 AF075009 R63109 R63068 428342 6712 1 AK056315 AI015524 AA724079 BI713619 AI377728 AW293682 AI928140 AI092404 AI085630 AA731340 BM469629 AW968804 AA425658
AA769094 BF446026 AW118719 AI332765 AW500888 AW576556 AI859571 AW499664 AW614573 AW629495 AW505314 W74704 AI356361
AI923640 AW070509 AI521500 AL042095 AA609309 AA761319 AI381489 H45700 AA761333 AW265424 AA909524 AA635311 AA649040
A1392620 Z40708 AI985564 AW263513 AA913892 AI693486 AW263502 AI806164 AW291137 BI061872 BI059498 AA134476 AW084888 AA036967
AW370823 T55263 BI002756 AA489664 BF827261 W74741 BF963166
450203 19009.1 AK055952 BG182168 BG220105 BG191569 BG188964 BG187388 BG220104 BG183714 BE645998 AI819354 AW974068 AI393635 AI580846
AI024796 AW020098 BI491127 AI393644 N74993 AW472959 BM478854 BI597437 H12165 BI458612 BE543192
432586 6633.1 BC022881 AU150944 BG750783 AW754175 AW857737 AI911659 AI050036 AA554053 AI826259 AA568548 450377 12109.1 AB033091 AL520743 BE811813 N53332 N99716 AL561910 AA280655 BE710392 AV705100 AW293978 AW444556 AA281459 AI679751 AI873695
BG700891 BI553517 R80518 BG779771 BG534451 AA479402AW961580 BF061430 A1857643AI768486AW512118 AA479302 AW770384
AW072470 AI041596 AI049699 AW592865 AA976261 BE879747 BG114119 AW183811 AA909938 BF571621 BF350794 BF351375 BE925699
AL050294 BC010371 BF982270 AL042656 BF095732 AW812618 BF095731 BG212397 BF678765 BI038602 BG388664 AW675337 BG289398
BE939598 AW805570 AA527097 AW150540 AI693720 AA743364 AI915793 N48185 AI573107 AA043474 AI351615 AI969490 AI910763 R50866
AI699181 N73808 H08164
436063 5483.1 AK000028 AA494483 AI298674 AA720773 AV761529 AI884670 AI936202 AW294235 D61652 BF881184 AV711384 N27154 AI926970 AV734970
N40094 N28596 AA884747 AA512890 BG436593
424036 6226.1 NM.033445 BC001193 AI885781 BF794032 AA476620 AA810906 AA810905 AI291244 AI885097 AI359708 AI335629 H97396 AI344589 AA300377
AA457566 AW771833 BE465621 AI364068 AI364452 AI648505 A1918342 AI928670 AA886580 AL531029 AA886344 AI186419 BG329096
BM045465 AL531028 BG437151 BE868021 AA179427
407819 7392.2 AK056626 AI800896 BF939022 BE644718 AI954754 BE218177 BE348567 AI962406 AW293122 AI968798 AI457321 BE327228 BG913531
AW939055T30280 R54166 Z43366 BG819153 BF003119 BE646274 BF940881 R18246 R42185
409151 4123.1 NM.004892 AF047442 BE275338 BF724863 BI917206 BE276993 AL602308 AA306105 BM152505 BC001364 AW993471 AW993481 AW993283
AW992919 AW992921 AW992980 AW992861 AW993220 BG573124 AA456385 AA234796 AI902726 AA354813 BI092644 BG778400 BI260001
BG007325 AI267455 AA426574 AI160782 AI472186 AA255500 AA434006 BG435520 AI356111 H00525 AV749060 BG944497 BG292031
AA902153 C04925AA902160AA383100AW073533AA256706AA150809 R65766AW958448 BE090972 BF693195AV738979 R65855 R80136
AA484677
422890 61426 1 AK057805 AW162343 AI190479 A1093318 BE048820 AI198397 AA654667 BE219303 Z39851 F02655 Z28734T16575 F10145 Z45266 AW572911
AW964436 AW004030 AI632565 BE502530 BI792383 BF056928 AA449241 AI651825 AA805324 AI264863 AW196918 AA948267 AI953735
AI263703 BF056387 AW594171 AI867447 AA319159 AI903440 AW956110 AI366013 AI867923 BG911906 D81142 C15616 AL538697 Z25032
Z43784 R13382 AV746924 AA449369 AA318815 BF364265 H17038 H10064 F04161 T87230 R40898 AW204071 BI819428 AA683393 AA683376
Z43192T74078T05103 F12527T77951 H10118 H17037 BF855407 R19603
451752 10408.5 AB032997 AI141678 AW978722 BE467119 AI761408 BF727385 AW237035 AI934521 BF436248 AI479668 Z40632 AA832081 AW295901
BF057835 BE465977 AI621269 BE4659838F756369 N74056 AI817896 AA716567 AA934774 H62600 H09497 BF943762 BE395335 BE883333
432363 1234917 1 AW970240 AA534489 AW970323
417379 1610005.1 AA196390 AA507837 AA196468
414922 1563.2 BG107484 AA632009 AI432670 AI656660 AI650884 AI521919 AI264653 AW150793 AW611894 AI917098 BI091245 AI651454 BF434889 AI580286
AI880735 BE301995 AI392959 AW613965 BM023628 AW515374 AI460102 BM023318 BE328188 AI952820 A1581363 AA557165 AI695677
AL562079 AI700926 AI470561 BF063058 AW196387 AU132984 BI064046 AI970157 R02122 H55924 AI521721 AA808206 AA725223 AI766003
AW339821 AA805951 AI287969AW664827
419733 7612.3 AK027321 W63676 W63789 BE046412 BF114614 BE646183 BM126230 AW044233 AI951970 AW663548 AI139947 AA514302 AA846232
BM126251 AA789002AA581966 AA809643AW188870 BE706664 BE706539 BE153177 BF084925AL133779AW961788 AA659693AA347970
AA295134 AA526037 AA449282 BG190454 H61476T91396 N20018T90114 H75644 BE710736 BF687723 H28581 AA249370 BF726698
BE841554 B1045099 T84625 AW129678 BG770826
432675 1237917,1 AW973834 AI791932 AI791855 AI732640 AA558833 AA559897 AI821610 410297 2990.1 BC013939 BI494690 BI491211 AI928393 AA843540 BG938644 AU185628 BI495842 AW173255 BM052709 A1743999 AI690144 AI922209 AI740907
AW340368 AA928759 AW118737 BF513970 AA707807 BF435295 AI339463 AI373842 AI433809 BE222392 AA602308 AA428261 AI460355
AW662760 AI888087 AI342098 AA722418 W78151 N64382 BE221848 AW025901 AA452120 AI150479 AI016166 AA779515 AA661791 BM474307
BI911169 BG575154AW953303T33604 D59141 AA385785AA148648 BM461961 BG681168 BI602483 BE889592AW954311 BM052986 BI962893
AI989299 Z42328 BF029504 T35668 BG402602 AU185770 A1023271 AA147719 AI434079 AI569000 AI276488 AA992453 AA342821 AA648303
AI349364 AI051008 AA926941 AA350894 AW071451 N22249 AI784138 AA083847 N22258 AW440825 AA661570 AA376687 AA659125 AI356299
R70463 AI383586 AA827189 BI494872 AW021094 BI494871 AA905500 AA460923 BI492041 AW028965 AI624611 BG271780 AI497723 H88862
D59858 N89979 AA658425 N81154 D62341 AI274437 N66697 H96993 AI370663 AA728850 H05232 R59374 H12223 AI935759 AI362553 D60006
N29572 AI916833 N75273 AA148710 BI597117 BG740471 AA332671 AA333874 AA643052 AW020175 R70550 BG623469 AA452342 AW965441
W19723 R32966 BE883841 R61003 AI910374 AI865262 R55325 A1468927 R34681 H96211 Z39807 BF954386
447620 687223.1 AI973051 AI400921 AI796154 AW241817AW290951 407192 2200202 1 AA602964AA609200 -134194 62680.1 AF119847 AA437261 AA436987 AI132965 448663 16112.4 BE966763 AA659765 AI961656 AI520918 AA761743 AA281477 N66431 BE463652 AA281329 AW272944 AA058687 BM145087 AA045516
AW341820 AA112515 AA258766 AI886639 AA714133 AA768245 AA035533 AI630459 T20165 AW971268 BE966269 AA522722
429163 1238297.1 AW974271 AA592975 AA447312 AA884766 426991 29771.1 AK001536 AK056135 BM474813 BE887303 AK022914 AW581996 AW812945 BE882302 AA134266 BI043873 AA019433 BI862088 BM468657
AU128438 BE384458 AL353967 BI857117 BF686525 BI465223 BM460132 AU129877 BI222283 BG171592 BI043544 BG496295 BG750710
BI256542 BG108520 AU150719 AW510354 AI554256 AL353968 AA191092 BF132635
432908 452541.1 AF150424 AI861896 AA570057 AV738855 433891 647290.1 AW182329 AA613792 T05304 AW858385 409960 39576.1 BE644758 AI082238 BF940027 AI201079 AI436035 AW275966 AI085394 AI291655 AW070441 AI474134 AI268978 AI769279 AI567682 AA693941
BF477668 AW664149 AA283782 BF509538 AW296868 AI268977 AI168133 BM352065 AI262769 BF941976 AI056920 AA481861 BF763697
AL565888 BM352383 AA427768 AA385346 AI186988 AA931831 AA134972 BF217480 BF111012 AA908246 AA319849 AA318136 AL514271
BF364291 AL515057 AV702312 AA377395 AL544217 AI341000 AW193583 AI350789 AA888338 BF945380 AW879092 AA130839 T91066 N92326
AI004389 AA078832 AL572370 W04622 BE314003 AW960808 BM360872 AA319160 AA130778 AL514257
414222 18695.1 BC021085 AL527872 AL526296 AL557087 BI255090 AU143499 AL560356 BG823170 BE736988 AU141388 AL580262 BI764173 AU120299
AU141755 AU141988 AU142941 AU141330 AU141784 BI770885 BI911394 BE901426 BI918039 BG760842 BE883026 BI254740 BE732690
BG430761 BE792868 AW328267 AL135173 AA102674 BF726986 AL564735 BE155962 BE155979 BF741679 H67776 H59234 H89665 AW117774
AW274435 L29008 NM 003104 U07361 BF002824 BI222949 AI458045 AW951537 BF196474 AI669049 AI042523 BE463928 AU160125 AU160580
AW069877 AW015214 AI948718 BE219706 AI953605 BE217755 AI991382 AI245005 BF431179 AI521843 BE048908 AI420449 AW275385
AA336950 BE501521 BF740566 AA311404 AA384639 BI772535 BG473076 BE891298 BE246928 BM012986 BE242693 BE901342 BG746358
BF374053 AL564430 AU143835 AI635707 BF195492 AI280559 BF741685 AA385257 BE247655 W94974 BE163702 AI025167 AI827118 N78641
AL581093 AU158964 AU158917 AI282516 AU146399 AA713947 AI285028 AA101228 AI338522 AA832316 AI284986 AA857926 BF372568
AA570172 AI753825 AA171566 AU159257 BM194320 W93390 AW132101 AA550898 BI259678 AA522554 N55172 AW013929 AI826274 AI871237
C75260 AA934846 AA555036 AA526579 AA526466 N80270 AI538347 AW615805 AU158875 AU158883 AU159396 AI016667 AU159238 AI282517
AA406317 AI285043 N53050 AA969446 N57718 H93323 W93374 AI873751 H56011 AI936174 AA937830 AW438877 AI800550 AW328268
AI244886 AA948424 AA700604 AA832317 AA011555 H97671 AA988711 AW150529 N70983 H44325 AV657614 AA902238 AA644018 AA034050
T71053 N71444 AA831158 T40892 AA706106
412652 18858.2 AI801777 BE677762 AW008210 AW009441 BE350994 BE207949 AI091475 AI802774 AI827533 AI075363 AI659979 AA687855 AI078125 AI090285
AA670058 AA602411 AA683472 AI436058 AA612826 AI038932 BG057726 AI167355 BF449023 AI289476 AW074381 BF972912 AI991780
AA889119 AI537472Z39730 AI868953 AI192337 BE812978 BE812939 AA115248 H99006 AI915784 F08973 T16748 D20468 AA609899 BF081234
AA115336 BE812876 BE812972 BE812982 BE813006 BE813019 R43883 BE812981
418166 18858.1 AK055915 BE867252 AI523348 AA765350 BF446858 Z43675 R19529 AL133837 BG389444 AW382942 BE702956 AA081961 BE835247 BE835308
BE835295 AA376302 BE645790 AA375690 AA376592 AW954423 N85732 AA249770 AI754416 AA213816 BF592044 AA811729 AW514842
AI633486 AI096810 AW183016 AI635738 N27524 BE645916 AI247842 AW991230 AI754277 H16814 AI766892 BF108422 AI800361 T95129
F11313 R97946 R93989 AA375242 BF109388 AI860939 AI680060 AW953899 BF971486 AI972337 AW953841 AA372437 AI216746 H11384
R38484 AA249043 AA249732
434747 117643 1 AW976537 AI033582 AA837085 AA745261 AA648395 437179 12239.1 AK055109 BC019085 AA187684 BG656226 BM023227 AI932311 AW264381 AA398371 BM021483 AI432433 AI375777 AI129580 AW262782
AA134107 BM023515 AA977504 AI859222 AI348454 R69725 AA975268 BM021207 AL080074 AA129218 AW207842 N90581 AA771919 AI092259
AI028416 AI074114 BG656536 BE501677 AW193419 AA917040 W90430 AI342984 AI378957 AL036486 AW020068 BI491093 BF476021 R41226
R69631 F04125 C02343 AA115589 R56480 AI400988 R54266 R31422
448044 1111791.1 AW867082 AI458682 H24240 R18426 R14537 424339 50559.1 NM 015720 AF219137 AL534420 AL524055 AL537346 AL538442 BG765888 AL530054 AL525377 BG474596 BG473144 BE251553 BG706099
AL538039 BG703131 BE255806 BF805256 F12128 AL566773 BI828686 BF761480 AI204971 BG818818 BI199246 AL534816 BF529941 AA324163
AL523285 BG914330 H07952 AL534815 BE769903 AI867802 BM310135 AL533702 BE254484 BF528852 BE867462 BE740130 AL134164
AL567115 AL533701 AL524054 AL515904 AL523284 AL568203 AL534419 BF981162 BE257148 AL561833
418259 133853.1 BM310925 AA426110 BM310629 BF434286 AW015091 BF475996 AW118867 BE675186 AI688568 AI453594 AW590589 AI652425 AI827969
BF056946 AI802866 AI393380 AI476224 AW590639 AW136271 AI458252 AI524726 AA843768 AA782158 AI336058 AI097532 AW451563
AA459408 AA459633 AA418444 W23607 BG940150 AI493445 AW054729 AI221929 AI868744 AA215405 AA766713 AA621546 BF928317
BE464132 AI990909 AW271459 AI262061 AA215404 N74332 BG940151 BG952261 AA972115 W96315 AA689586 R69057 BF766886 BE769254
W05240
411089 5597.6 BI009308 BI009893 BF922023 BF922909 BF922913 BF922096 BF957733 BE701791 AA456454 AA579876 BF933710 AA091294 BI007291
AW905577 AW975593 AA713730 AW836781 AA666384 AA551106 BF594606 AI082382 AI955808 AI679895 AI679386 BF435555 AA586369
AA551351 AA595822AA565188 BF808855AA584921 N86077AA601031 M633188AA514764 AA454562AA551297AA936109 BI009389
AW897806 BE815442 BF739374 BI009310 BF925422 BF933709 BF922034 BF925465 BI009680
431416 120918.1 AW969151 AA532718AA504784AI791194AI821930AI821485 F37127AA654206 F27974 434974 77302.1 AL079283 BF792538 AA744861 AI871888 AI478580 AI720775 AI888937 AI808966 BE463436 BF725510 AW675767 BF589111 BE855951
AW197232 AW272173 AI480335 BF589044 AA443540 AI420128 AI056029 AI650755 AW274589 AW183510 AI440198 AI271801 AW080345
AW189506 AW008293 AA884731 AA579802 AI968645 AI620822 AI222117 AA677146 AI346296 BI792788 AA446615 AI 83488 AA897113
AW271851 AW241299 W90134 AA482921 AI049496 AA492010 AA846639 AA983603 AA969293 AI890036 BI254992 AA463513 AA476659
AW673442AL557763AA868312 H28886AA778711 AA081838 AI989340 AL557762 N99654Z28545 N28874AA442388AW887818AW663156
BG252539 BG501262 BG714174 BG499052 AA058524 BE881198 C75278 R59648 AI829311 AA037656 AW026747 N64518 AW103253 BF529731
AW241677 AW194855 AA917531 R96578 H94036 AA856665T10342 AW439112 AI090044 AA661591 N71704 AI474928 AU152235 D53426
N21634 R59590 R51072 R96601 H06171 AA084440 H84172AW118714 C04928 W90092 AA039267 AA136445 R52391 T66024 BG778916
AA428153 N41394 AA283639 R96600 H94122 BF743684 AA147009 T65867 Z19487 BF697478
431155 1235742 1 AW971213 AA493925 AA493567 AA876839 AA934462 409927 2333801.1 T69981 T69924AA078476 447881 44623 1 AK074291 AW293424 BE676135 AI832125 BE019146 BE465019 AI761124 AA617778 AI279232 AW575897 AI672039 F28618 BF924261
AA722184 BF934174 BE004328 AV749301 BE880282 BI019798 BI019389 BF928776 AW813409 AV726604 AA077560 BE272975 BF949119
AW814195 BE879126 AI697926 BF594155 BE205787 BF063513 N35828 AI948557 AI433839 AI379679 BG056182 AI589094 N23123 AA588805
AW316581 AI080272 AI421980 AI493318 BF194830 N87590 AA495993 N32996 AA699844 H96845 H96592 N28741 BI035539 BF747723
BF171066 W01350 H05495 AI243785 Z39622 AA887432 AI350659 R46102
433009 2142268.1 AA761668 AA573621 R09670 R92814 412719 1634.2 BI918715 BF594193AI073494AI363077 AI656655AA121979 BF983131 AA491795 BG152545AI350401 BF939121 AI479401 BI493099 BF057693
AI970550 BF111919 BF448282 BI493100 AW043768 AW006202 AI564010 BF433292 A1458202 AI954746 BE220962 AI375411 AI361048
AA115853 AI364474 AI669815 AA133407 AI928647 AW016610 AA133334 AA504948 AI291629 AI161208 AA837042 AI867138 AA987255 AI830219
AU150404 AI680674 AW969901
437050 1240141.1 AW976442 AA743319 AA766420 436823 MH1660 153 BG180003 AW975741 AW749865 AA731828 AA731829 457733 119160.1 AW974S12 AI821822 AI821820 AI821075 AI821073 AA651643 AA651662 453912 32562.3 BM472224 BI966849 BI966735 AW973032 BI962894 BI963048 AA548765 AI926504 AA041551 AW043754 AI086702 AW008105 AA974849
AW614893AA553737AA916996AW262982AI580991 BF726843AV693312 W35325AA039927 BG460936AW388482AW3884208F374777
W01360 N94710 H87967
440080 517737.1 AW051597 AI733052 AI167287 AI732999 AI566918 AI476787 AI791542 AA887204 AW025394 AA863338 AI240285 AI791393 419175 35068.1 AB018322 BC012480 BI524873 AW665554 AI934469 AI479916 BF096179 BF096162 BF096132 AA744972 AI951988 AI858339 BE076331
AA886998 AI570585 AI916688 AI678811 AI693109 AI308135 AA669046 AA961064 AI018062 H80618 BE221942 R52609 AI915164 AA365626
Z44671 BI052776 BF882486 BG286184 AI589558 AA931663 AA534979 AI275392 AI273455 R52553 AA829920 H80652 AA360728 F10618 AW953666 AW176773 H85527 AA765570 AA081927 BF093262 BG743753 AL037576 AA534314 BE814964 BE973713 N49493 BE006634
BE006630 AW270037 AA234765 AI334004 BF057179 AI857450 AI341191 AI434143 AI917449 AW517207 AA255424 AW008334 AA847572
AA994211 AA861901 AA581873AI580157AI364363AW242357AW235291 N55645AA319869 R36911 AA256551 AW044188 AI203159 N49403
F02090 AI187299 AI609644Z40516 AW952314
421091 24941.2 AK057700 BC015899 BE867108 AL526926 AL527436 BG913023 AI884867 BE858461 AI885227 AI935218 BE645596 AI922406 AA778161
BF345973 AW195853 AI687121 AI336147 AI091364 AI769203 AW627859 BE677432 BF439954 BG820230 AA283686 AA812396 AI358396
AA932022 BE222681 AW0161O9 BM352667 BF528099 BG818616 AI935916 AA912295 BG910887 AL568301 AL567278 BI522445 BI754384
BG819375 BF835950 AA323718 AA860955 AI089847 AL520776 AL526045 AL538507 AL567798 AL536876 AL574332 BF834531 BF340116
BF835954 AL573997 AL581252 BF957667 AL580170 AW952324 AL569382 AW148695 AL559234 BG034270 BI913839 AL581327 AL565842
H43568 BF945188 AL559686 AL539326 T15481 AW895092 AL582684 BI519896
441128 20932.1 BC014072 BE328850 AI356567 AI148171 AI022165 BG149661 BF000671 AA233101 AA573721 AA447991 AW016855 AI005068 AA554071
BF478215 AA906902 AW014761 BE905651 BE512923 BM047129 AA243852 AA232991 AA127550 AA127551 AA570256 AI473237 BF033706
N90525 AW973623 AI359627 BG674574 BE903322
406789 0.0 AI041403 Z49148 410099 16732.1 AK055674 AW965247 AV751598 AA290926 R53043 AA331387 AK056148 BI917678 BG819395 BG911971 BG820167 AI174254 AA348720
AA364503 BG714279 AW893230 AA081774 H24222 AV727176 BF875715 AA081630 BE000834 AA334880 AL563737 BG029709 W52882
AI439658 BE551237 AA283724 BF109530 AI457096 AI805992 BE467736 AA693467 AI697593 AI887863 AI167419 AW901980 AW901768
BE702179 AA484549 T23811 BE327043 AA716027 AA917004 AA167714 BF339675 AA084618 AI418634 T31586 AA436630 AI366472 AA706191
AI422304 AI204899 AI041169 AA211402 AW827081 AA788593 T32736 AI767935 AA747914 T03534 AW959843 AL119527 BE327037 AW901982
AW993370 AW901977 AW902071 W60090 N79906 D52685 T07735 BE702069 BE702172 T08671 BE767121 BE767117 BE767113
432745 112643.1 AA658826 AI821926 AI791191 AA635129 AA564492
400263 18977.1 Z11692 X51466 NM 001961 M19997 BI224253 BG830478 AU122147 AU123437 BG113591 BG752624 BE886804 BI868669 BG337216 AW629935
BM016525 AI560409 AL562866 AI909178 BF849556 AA371735 BF038841 BF727115 BC006547 BG757526 AL555664 BI261304 BG770095
BI033486 BI517580 BG876486 BI011828 AI313235 BG831724 BF869862 BG998348 BI011834 BF888337 BF898627 BF092380 AW803215 F01241
BF805719 BG8764S7 AW498536 BF988866 BG998849 AA248724 BG829202 BG756456 BG032392 BI859287 BM016990 BG332369 BE933685
BE166758 BM452445 AI937808 AW026128 N23684 AW006041 AI337621 F33111 BF344301 BG105450 BG387343 BF569547 BF154671
BM007368 BF569385 BE772007 BI199487 BF761700 BI261519 BF944452 BF898506 AI038390 BM044934 AW381142 BG743618 BE769206
BE893973 BI015047 BF886479 BF761350 BE769769 BG766117 BF847365 BE397834 AW371121 BF089125 BE082996 BF183193 BG180964
BF089940 BI000274 BG255503 BG674499 BG774174 BI015084
411605 10026.3 BG256892 H10532 N46614 R52610 AW977696 BM460488 W56819 BI042183 BG977498 BE767451 BF870009 BG477472 R61137 R14274 R20259
R09686 BI838226 BF034269 AA429173 BE741829 AW867495 AI123683 AW006831 BE831162 AW452753 AV742717 W86152 BF115102 AI633815
BF921562 AA094230 BE092587 W86151 AA526153 AI672156 BF914496 R12579 BF852352 AA699780 T57386 BF903022 R09933 AA678298
445636 8561.5 BF339388 AI345516 BG391657 BE708967 BG026034 BE261703 H56716 H65572 H93801 T48830 R96953 R96989 R39707 BE867593 AA090310
AA090672
420223 191648.1 N27807AA256634 BE276324 423476 32437.1 AF263306 BF951698 T66089 F11783 F11794 H29379 R19493 H18042 AL133995 AW134660 AI299437 AA057405 AA917450 AI002692 T09262
R43839 H29290 T65008 N78357
441054 2641490 1 AI221207 A1659856 AA913591 AI220302 429925 33135.1 NM.000786 U23942 BI601050 BG771947 BG773455 BI561558 BI460206 BG714348 BM126447 AU 129411 AU129401 AL119303 AV724389
AU099323 AU127089 BG701614 BM150364 D55653 AV702235 BE090408 AU151526 AW149661 BG054754 W42624 W52098 AV709923 W79867
W74235 AV709052 AI217668 AA399409 BE182318 BM128040 AI693998 AW615411 AW070426 A1124550 AW778736 AA477781 AW263013
AI459619 AA860513 BF809548 AA643635 AA864975 H42020 AW901189 AA904786 BF432722 BI916393 BM470755 BI333211 AA095636 BI256415
U47727 BG773392 N58531 AA226450 BG679564AA292178 W56883 BE813131 C03646 BG287974 AA386261 H47580 48858 T91611 H42019
BI869421 BG502073 BG425943 W37290 W31363 BE004451 BF208311 BI048717 N78122 AA226597 AI525334
434976 121716.1 AI963821 AA657925 AA935436 AW975068 440191 MH790.2 BC000222 AL136871 NM 032261 BC009497 BM461705 BG470749 BG826905 BG285127 BI253235 BE397026 BG704967 AW961225 BM352817
BI227161 BG820180 AA454463 AA255685 N31549 AA326504 BC019924 BG257230 BI092368 BI869896 BG251883 BF034444 BG286577
BE260391 AA599912 BF686779 AI755222 AA452272 AW241170 AU156565 F28259 T16319 AA362506 N64153 BM016416 BM458963 BG739972
AV729565 BE268285 BE867433 BM011110 BG285856 AI922439 BE270975 AL119339 BF956085 AI565178 AL554305 AL573240 AL572917
AI129627 AL546640 BE392285 AI092843 AI371057 BE302410 A1608753 AW674261 AI750057 AI052649 N47822 AL516249 AI589903 BG258439
AI123662 AI126014 AA778101 AA243218 AW498837 AA748311 AI754395 T15728 AA775369 AA858195 W73625 AA216784 AW513778 AW243958
AI061112 AI783806 AL569622 AA070466 BF229936 N58159 H80288 N32598 H80293 H80279 AL581253 AW571884 AI361698 AW073321
AA876464H95640T34421 AA331419 N99897 H80274 BI262120 AA205826 AA070716 AA653206 AA653483 BG389811 W20432 AA670295
AA653197 D51888 AA362527 BG056668AW118162AW073071 BE293868 BF792321 BF792258 BG107176T56604 BM193566 H03238AA618045
AA906004 BI08S686 AA564566 AI221630 D52045 C14510 AA029390 W60153 H98743 AI682641 H28485 AA723093 AI081730 AA641309
AA687083 BI224818 AW204722 AI309186 AI215122 AI200785 BE467373 BM352502 AI304400 AI193071 AI742483 AW003408 AI400201 AI656740
AW665173 AI215120 AI147599 AI803429 AI076110 AI754349 AW205103 AI262491 AI808243 AI281007 AI051273 AI004801 AW768918 AW103289
AI474637 AI264446 AI699509 BE704420 AA989278 AA918256 AA830956 AA989425 AA911929 AA262598 BE740563 BE727592 BE781003
BG030940 BE256750 W23528 AL517059 H95714 W00970 H74304 W32684 H38210 BE617658 AW593584 AA580593 H94863 N69544 AA181762
D20132T55734T60692 R76858AA022948 AW770291 R50934AA205918 R97811 H40328 R86252AA936029 AI813809 AA933607AA129695
AA548261 AA714393AA775006AA653439AA983808AA743251 AA401150AA581651 AA555005AA554408 D51494 C13991 D51478 D52007
AA489663 D52138 D51696 D55942 D52740 AI000118 AL516304 AL534259 N54940 AL579194 AI669399 AI342925 BE939201 AA633000 BI222963
AI619676 AW190306 BF035010AW087897AI864969T57243 R48211 AA113880 R26594 C14467 C14444 BI195459 BE896346 BE270780
AL568073 BG389833 BE891549 BI223147 AW381001 AA448464 AW799744 AA412194 AA948107 AA927157 AA983841 BF752571 BE731304
440409 588375 1 AI380443 AI240179 AA977516 AA884643 AW079380 AW294316 AI913755 AI864320 AI685770 H25135 A1972654 AI538592 444610 2145292.1 AI174783 R12271 R83569 446091 515091 1 AI274757 AI559500 AW022192 431843 445334.1 AW970134 AA516420 AA543007 BG057526 BI001430 AI498371 D60181 D81004 D60382 C15876 N91070 C14815 C15068 D80763 C14818
C15161 D60184 D60656
400262 18977.1 Z11692 X51466 NM.001961 M19997 BI224253 BG830478 AU122147 AU123437 BG113591 BG752624 BE886804 BI868669 BG337216 AW629935
BM016525 AI560409 AL562866 AI909178 BF849556 AA371735 BF038841 BF727115 BC006547 BG757526 AL555664 BI261304 BG770095
BI033486 BI517580 BG876486 BI011828 AI313235 BG831724 BF869862 BG998348 BI011834 BF888337 BF898627 BF092380 AW803215 F01241
BF805719 BG876487 AW498536 BF988866 BG998849 AA248724 BG829202 BG756456 BG032392 BI859287 BM016990 BG332369 BE933685
BE166758 BM452445 AI937808 AW026128 N23684 AW006041 AI337621 F33111 BF344301 BG105450 BG387343 BF569547 BF154671
BM007368 BF569385 BE772007 BI199487 BF761700 BI261519 BF944452 BF898506 AI038390 BM044934 AW381142 BG743618 BE769206
BE893973 BI015047 BF886479 BF761350 BE769769 BG766117 BF847365 BE397834 AW371121 BF089125 BE082996 BF183193 BG180964
BF089940 BI000274 BG255503 BG674499 BG774174 BI015084
TABLE 68C
Pkey: Unique number corresponding to an Eos probeεet
Ref: Sequence εource. The 7 digit numberε in thiε column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled "The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489495. Strand: Indicates DNA strand from which exonε were predicted.
NLpoεition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLposition
403047 3540153 Minuε 59793-59968
401424 8176894 Pluε 24223-24428
401451 6634068 Minuε 119926-121272
401747 9789672 Minuε 118596-118816,119119-119244,119609-11976
404632 9796668 Pluε 45096-45229
403046 3540153 Minuε 55707-55859,56369-56511
404922 7341893 Pluε 13248-13428
401519 6649315 Pluε 157315-157950
401197 9719705 Plus 176341-176452
401866 8018106 Plus 73126-73623
405387 6587915 Minus 3769-3833,5708-5895
403752 7678857 Pluε 33704-33828
404210 5006246 Pluε 169926-170121
401785 7249190 Minus 165776-165996,166189-166314,166408-16656
406214 7342036 Plus 86320-86523
403532 8076842 Minus 81750-81901
400860 9757499 Minus 151830-152104,152649-152744
404913 7341740 Plus 97717-97976
Table 69A lists about 200 genes that are upregulated in human umbilical vein endothelial cells (HUVEC) compared to normal body tissues. These geneε were εelxted from 59680 probeεetε on the Eoε/Affymetrix Hu03 Genxhip array. Gene expreεεion data for exh probeset obtained from this analysiε waε expreεεed as average intensity (Al), a normalized value reflxting the relative level of mRNA expression.
Table 70A lists about 148 genes that are downregulated uεing the mean of vessels (veins and arterieε) compared to the mean of HUVEC. These genes were selxted from 59680 probesets on the Eos/Affymetrix Hu03 Genxhip array. Gene expression data for exh probeset obtained from thiε analysis was expresεed aε average intenεity (Al), a normalized value reflxting relative level of mRNA expresεion.
TABLE 69A:
Pkey: Unique Eoε probeεet identifier number
ExAccn: Exemplar Accession number, Genbank xceεsion number
UnigenelD: Unigene number
Unigene Title: Unigene gene title
R1 : Ratio of the mean of HUVEC Al's to the mean of the nomial body tisεue Al'ε
Pkey ExAccn UnigenelD Unigene Title R1
424806 AA382523 Hs.105689 MSTP031 protein 1.51
418036 Z37976 Hs.83337 latent transforming growth fxtor beta b 1.94
444381 BE387335 Hs.283713 ESTs, Weakly similarto S64054 hypotheti 1.60
442802 AL133035 Hs.8728 hypothetical protein DKFZp434G171 1.73
417944 AU077196 Hs.82985 collagen, type V, alpha 2 1.48
410480 R97457 Hε.63984 cadhenn 13, H-cadherin (heart) 1.91
452516 AA058630 Hs.29759 RNA POLYMERASE I AND TRANSCRIPT RELEASE 1.59
425139 AW630488 Hs.25338 protease, serine, 23 \ 1.63
402463 NM_014624:Homo sapieπε S100 calcium-bind 1.50
423798 AF047033 Hε.132904 solute earner family 4, sodium bicarbon 1.31
412568 AI878826 Hs.74034 caveolin 1, caveolae protein, 22kD 1.53
419948 AB041035 Hs.93847 NM_016931:Homo sapienε NADPH oxidase 4 ( 2.06
447526 AL048753 Hs.303649 small inducible cytokine A2 (moπxyte ch 2.10
446500 U78093 Hε.15154 εuεhi-repeat-containing protein, Xchrom 1.67
441457 AW996651 Hs.43838 ESTs 1.30
408296 AL117452 Hs.44155 DKFZP586G1517 protein 1.61
418994 AA296520 Hs.89546 selxtin E (endothelial adheεion olxul 1.87
413795 AL040178 Hε.142003 ESTε 1.64
441689 A1123705 Hε.289068 ESTs 1.44
412567 AI750979 Hs.74034 Homo sapienε clone 24651 mRNA εequence 1.75
424432 AB037821 Hs.146858 protocadherin 10 1.65
432673 AB028859 Hε.278605 DnaJ (Hεp40) homolog, subfamily B, membe 1.31
418683 U90908 Hε.87241 hypothetical protein from clones 23549 a 1.42
453085 AW954243 KIAA0251 protein 1.47
438887 R68857 Hs.265499 ESTs 1.49
436729 BE621807 transmembrane 4 superfamily member 1 1.91
400494 ENSP00000238970*:CIG30 (Fragment). 1.34
442506 BE566411 ESTs 1.54
425023 AW956889 Hs.154210 endothelial differentiation, sphingolipi 1.55
414476 AA301867 Hs.76224 EGF-containing fibulin-like extrxellula 2.65
452933 AW391423 Hs.288555 Homo sapiens cDNA: FU22425 fis, clone H 1.62
422389 AF240635 Hs.115897 protocadherin 12 1.38
417124 BE122762 Hs.25338 ESTs 2.13
433681 AI004377 Hs.200360 Homo sapienε cDNA FU 13027 fiε, clone NT 1.31
419983 W55956 Hs.94030 Homo εapienε mRNA; cDNA DKFZp586E1624 (f 1.54
414776 AA155598 Hs.212839 hypothetical protein FU14195; KIAA1714 1.51
450534 AI570189 Hs.25132 KIAA0470 gene product 1.43
449618 AI076459 Hs.15978 KIAA1272 protein 1.42
446098 AW072215 Hs.208470 ESTε 1.53
413281 AA861271 Hε.222024 transcription fxtor BMAL2 1.40
448674 W31178 Hε.154140 ovary-spxific xidic protein 1.47
407061 X97748 gb:H.sapieπs PTX3 gene promotor region. 1.33 434846 AW295389 Hs.119768 ESTs 1.29
408570 AL046406 Hs.103483 KIAA1798 protein 1.47
436772 AW975688 metallothionein 1E (functional) 1.81
453789 AA628517 Hs.118502 ESTs 1.41
424259 AK001776 Hε.143954 hypothetical protein FU10914 1.35
441020 W79283 Hε.35962 ESTs 1.62
401234 mitogen-xtivated protein kinaεe 8 inter 1.48
420174 AI824144 Hε.199749 ESTs 1.75
445684 AK001696 Hε.13109 Ran binding protein 11 1.49
418693 AI750878 Hs.87409 thrombospoπdin 1 1.89
426535 AU077012 Hs.288582 ESTs, Weakly εimilar to ubiquitous TPR m 1.77
412330 NM.005100 Hε.788 A kinase (PRKA) anchor protein (gravin) 2.02
412646 NM.006825 Hε.74368 transmembrane protein (63kD), eπdoplasmi 1.64
434523 AA703709 Hε.23410 translxase of inner mitxhondrial membr 1.26
433376 AI249361 Hε.74122 caspase 4, apoptosiε-related cyεteine pr 1.49
422099 AA156022 Hs.111518 hypothetical protein 1.56
449394 AA004368 Hs.18160 Homo εapieπε cDNA FU11550 fis, clone HE 1.54
445119 AF035121 Hs.12337 kinase insert domain rxeptor (a type II 1.40
438142 T90309 Hs.269651 ESTs 1.45
437478 AL390172 Hs.317432 branched chain aminotransferaεe 1, cytoε 1.44
422809 AK001379 Hs.121028 hypothetical protein FU10549 1.42
453459 BE047032 Hs.257789 ESTs 1.51
442711 AF151073 Hs.8645 hypothetical protein 1.42
428428 AL037544 Hε.184298 cyclin-dependent kinase 7 (homolog of Xe 1.32
400288 X06256 Hε.149609 integnn, alpha 5 (fibronxfin rxeptor, 2.67
417640 D30857 Hs.82353 protein C rxeptor, endothelial (EPCR) 2.47
407252 AA659037 Hs.163780 (AB075832) KIAA1952 protein [Homo sapien 1.76
418825 AA228881 Hε.22394 hypothetical protein FU10893 1.40
417805 U38545 Hs.82587 phospholipase DI, phophatidylcholine-spe 1.35
426828 NM 000020 Hs.172670 xtivin A rxeptor type ll-like 1 1.55
415714 NM 002290 Hε.78672 laminin, alpha 4 1.90
446984 AB020722 Hs.16714 Rho guanine exchange fxtor (GEF) 15 1.71
421778 AA428000 Hs.283072 xtin related protein 2/3 complex, εubun 1.88
421218 NM 000499 Hs.72912 cytxhrome P450, εubfamily I (aromatic c 1.75
452298 AI039243 Hs.278585 NM.024756; Homo sapiens hypothetical pro 1.86
434596 T59538 gb:yb65g12.s1 Stratagene ovary (937217) 1.52
412351 AL135960 Hε.73828 T-cell xute lymphxytic leukemia 1 1.61
433374 AI821409 Hs.304471 EST 1.45
429113 D28235 Hs.196384 prostaglandiπ-endoperoxide εynthase 2 (p 2.14
423099 NM 002837 Hε.123641 protein tyrosine phosphatase, receptor t 1.50
435705 AA782114 Hs.28043 ESTs 1.53
456999 AA319798 Hs.298581 eukaryotic translation elongation fxtor 1.52
453983 H94997 Hs.16450 ESTs 1.94
406506 Target Exon 1.97
424503 NM 002205 Hs.149609 integnn, alpha 5 (fibronxfin rxeptor, 2.32
452924 AW580939 Hs.97199 complement component C1q rxeptor 2.36
426696 AW363332 Hs.171844 NM.006505 Homo sapiens poliovirus rxept 1.61
418941 AA452970 Hs.239527 E1B-55kDa-assxiated protein 5 1.41
450152 AI138635 Hs.22968 intron of VEGFR 1.70
437269 AA334384 Hε.149420 ESTs 1.60
445279 R41900 Hε.22245 ESTs 1.59
409509 AL036923 Hε.322710 ESTs 1.52
410240 AL157424 Hs.61289 synaptoj'anin 2 1.61
424711 NM 005795 Hs.152175 calcitonin receptor-like 1.96
449318 AW236021 Hs.78531 Homo sapiens, Similar to RIKEN cDNA 5730 1.81
407862 BE548267 Hs.337986 Homo sapfens cDNA FU10934 fis, clone OV 1.91
410057 R66634 Hε.268107 multimerin 1.85
446727 AB011095 Hs.16032 KIAA0523 protein 1.67
412564 X83703 cardix ankyrin repeat protein 1.51
414786 AI246482 Hs.243010 Homo sapienε raε homolog gene family, me 1.71
410276 AI554545 Hs.71832 aπgiopoietin-2 1.91
406627 T64904 Hs.163780 ESTε 1.76
405025 Bone morphogenetic protein 6 1.69
422648 D86983 Hs.118893 Melanoma aεsxiated gene 2.33
452852 AK001972 Hs.30822 hypothetical protein FU11110 1.78
427912 AL022310 Hs.181097 tumor nxrosis fxtor (ligand) superfami 1.79
432004 BE018302 Hs.2894 plxental growth fxtor, vascular endoth 2.02
430129 BE301708 Hs.233955 hypothetical protein FU20401 1.93
429276 AF056085 Hs.198612 G protein-coupled rxeptor 51 1.65
407704 BE315072 Hs.78768 malignant cell expreεsion-enhanced gene/ 1.48
448694 AA478756 Hs.194477 E3 ubiquitin ligaεe SMURF2 2.01
434398 AA121098 Hs.3838 εerum-inducible kinase 1.83
416851 AW963951 Hε.85618 ESTs 1.65
412420 AL035668 Hε.73853 bone morphogenetic protein 2 1.69
416179 R19015 Hε.79067 MAD (mothers against dxapentaplegic, Dr 1.71
450689 AI369275 Hs.243010 Homo sapienε cDNA FU14445 fis, clone HE 1.86
416658 U03272 Hs.79432 fibrilliπ 2 (congenital contrxtural ara 1.65
425235 AA353113 Hs.112497 Homo sapiens cDNA: FU22743 fis, clone H 1.83
428206 AB020643 Hs.183006 KIAA0836 protein 1.77
412755 BE144306 Hs.179891 ESTs, Weakly similarto P4HA_HUMAN PROLY 2.00
456977 AK000252 Hs.169758 hypothetical protein FU20245 1.61
456977 AK000252 Hs.169758 hypothetical protein FU20245 1.61
427897 NM 01741c I Hs.303084 apelin; peptide ligand for APJ receptor 1.94 425234 AW152225 Hs 165909 ESTε, Weakly similar to I38022 hypotheti 174
444409 AI792140 Hs 49265 ESTs 1 88
421340 F07783 Hs 1369 decay accelerating fxtor for complement 1 74
445701 AF055581 Hs 13131 lymphocyte adaptor protein 218
444009 AI380792 Hs 135104 ESTs 1 90
409220 BE243323 Hs 51233 tumor nxroεis fxtor rxeptor superfami 216
416940 N75620 Hs 43157 ESTs 203
418922 AW956580 Hε 42699 ESTs 209
431548 AI834273 Hε9711 novel protein 1 81
434927 H46612 Hs 293815 Homo sapienε HSPC285 mRNA partial eds 2 14
434558 AW264102 Hs 39168 ESTs 1 93
438183 BE263252 Hs 6101 hypothetical protein MGC3178 205
428438 NMJ01955 Hs 2271 endothelin 1 246
453365 AA035211 Hs 17404 SOX7 SRY (sex determining region Y) box 220
418058 AW161552 Hs 83381 guanine nucleotide binding protein 11 226
439410 AA632012 Hs 188746 ESTs 1 93
453467 AI535997 Hs 30089 ESTs 239
420209 AA256444 Hs 126485 hypothetical protein FLJ12604 KIAA1692 1 84
417933 X02308 Hs 82962 thymidylate synthetase 1 70
436420 AA443966 Hs 31595 ESTs 1 97
414430 AI346201 Hs 76118 ubiquitin carboxyl terminal esterase L1 1 93
412140 AA219691 Hs 73625 RAB6 interxting kinesm like (rabkmes 180
442104 L20971 Hs 188 phoεphodieεteraεe 4B, cAMP εpxific (dun 203
425397 J04088 Hε 156346 topoisomerase (DNA) II alpha (170kD) 1 58
418506 AA084248 Hε 85339 G protein-coupled rxeptor 39 181
413745 AW247252 Hs 75514 nucleoside phosphorylase 1 99
405121 mitogen-xtivated protein kinaεe 8 inter 299
425811 ALO39104 Hs 159557 karyophenn alpha 2 (RAG cohort 1, impor 1 76
415765 NM 005424 Hε 78824 tyrosine kinase with immunoglobulin and 213
431089 BE041395 Hs 156110 ESTs Weakly similar to unknown protein 271
421937 AI878857 Hs 109706 hematological and neurological expressed 1 65
408669 AI493591 Hs 78146 platelet/endothelial cell adhesion olx 239
416815 U41514 Hs 80120 UDP N xetyl alpha-D-gatectosamine polyp 1 77
418203 X54942 Hs 83758 CDC28 protein kinaεe 2 1 67
408243 Y00787 Hs624 interleukin 8 209
418054 NM 002318 Hε 83354 lyεyl oxidase-like 2 242
407891 AA486620 Hs 41135 endomucin 2 234
407891 AA486620 Hs41135 eπdomucin 2 234
436032 AA150797 Hs 109276 latexin protein 224
439382 BE247684 Hs 103070 ESTε 207
419172 AW338625 Hs 22120 ESTε,sιmιlar to TRANSMEMBRANE 4 SUPERF 200
442006 AW975183 ESTs, Weakly similar to S72482 hypotheti 233
447560 AF065214 Hs 18858 phospholipase A2 group IVC (cytosolic, 211
432128 AA127221 Hs 296502 ESTs 227
417426 NM 002291 Hs 82124 laminin, beta 1 211
434217 AW014795 Hs 23349 ESTs 203
439265 AL134430 Hs 6906 Homo sapiens cDNA FU23197 fis, clone R 208
442923 AW248322 Hε 95835 ESTs Weakly similarto unnamed protein 1 57
433001 AF217513 Hs 279905 clone HQ0310 PRO0310p1 1 60
418741 H83265 Hs 8881 ESTs, Weakly similar to S41044 chromosom 237
442573 H93366 Hs 7567 branched chain aminotranεferase 1, cytos 255
422544 AB018259 Hs 118140 KIAA0716 gene product 209
449722 BE280074 Hs 23960 cyclin B1 176
413794 AF234532 Hε 61638 myosin X 201
422603 BE242587 Hε 118651 hematopoietically expressed homeobox 215
406964 M21305 gb Human alpha satellite and satellite 3 308
448231 AI701916 Hs 202509 ESTs 227
408989 AW361666 Hs 49500 KIAA0746 protein 143
429663 M68874 Hs 211587 phospholipase A2, group IVA (cytosolic, 267
418738 AW388633 Hs 6682 solute earner family 7, (cationic ammo 218
418185 AW958272 Hs 347326 intercellular adhesion molxule 2 260
417308 H60720 Hs 81892 KIAA0101 gene product 1 86
407975 X89426 Hs 41716 endothelial cell spxific molxule 1 292
420256 U84722 Hs 76206 cadhenn 5 type 2, VE-cadheπn (vascula 292
400666 NM.002425 Homo sapienε matnx metallopro 259
431728 NM 007351 Hs 268107 mulfimeπn 272
440086 NM.005402 Hs 288757 v ral εimian leukemia viral oncogene hom 225
413132 NM 006823 Hs 75209 protein kinase (cAMP-dependent catalyb 1 76
451979 F06972 Hs 27372 endothelial tyrosine kinase (Etk) (BMX), 337
415138 C18356 Hs 295944 tissue fxtor pathway inhibitor 2 311
414577 AI056548 Hs 72116 hypothetical protein FU20992 similarto 311
444330 AI597655 Hs 49265 ESTs 308
422424 AI186431 Hs 296638 prostate differentiation fxtor 296
400289 X07820 Hs2258 matnx metalloproteinase 10 (stromelyεm 484
418007 M13509 Hε 83169 matnx metalloproteinase 1 (interstitial 11 91
TABLE 69B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Acceεεion Genbank acceεεion numberε
Pkey CAT Number Accession 453085 100171 BC017336 BG716430 BG501286 BI458528 AI582223 N98532AI338138 AI273442 A 102617 AA831177 AA745642 AA412583 AA355375 BG547492 AW954243 BI766546 BG057641 AI192435 AI338935 AI312651 AI708679 AH 91125 AI206832 AA676899 AI078010 A1888718 AA452830 BF445542 N69930 AA715017 BF446713 BE046852 AW771909 AA907729 AI143749 AI761290 AA890233 BF925759 AI783713 AI767267 AA814538 W56778 AA918481 BG743526 BE645242 AI025328 AI298436 AI290445 H27710 AI475034 BG740023 AI090348 AI340003 BI602481 W38495 AI183314 AI927418 BG397181 AA878310 W19369 W56507 C05751 AW380760 AW380770 AW380790 BF930729 H28425 AA037326 AA375805
436729 6624_1 X75684 AL573167 AI445461 AI453743 AI983655 AI564644 AA977180 AI694111 AI591358 AW071625 AI678712 AI720939 AI927769 BE439796 AI963432 AA292956 AW192593 AI865838 AI696905 AI424384 AI161312 AI911921 AI597801 BI494959 AI240988 AI492554 AW262737 BE044033 AW008570 AW629505 BI494958 AA088439 AA706057 BF222820 BF593608 BE501957 AA524526 BE044134 AW572531 AW015724 BE349186 AA043217 BE219784 AI799814 AA129575 AI671727 AI470033 BE646195 AW779725 AA903050 AA147228 AA404570 AI075878 W38161 AI972739 AW673152 AA723200 C06123 BF057147 AA627686 AA157944 A1990245 AA662517 T32487 AI800106 AI333170 A1859160 W45410 AI990827 AW275048 AA182640 AA478328 AI298935 AW085158 AW471421 AW103470 AW300456 AW191997 AI823466 AA962397 AA136658 AI251817 AW339104 AA724739 AA411100 AA191349 AA757735 AA037696 AI769516 AW772283 AA010631 AI692846 AI061065 H80983 R79933 AI950693 AI245632 AI349390 AA148284 AI798502 AA487893 AI621320 AW194272 C06365 AA953883 BE858936 AI918523 AI872628 AI927217 AI453453 AI189366 AW338678 AI261359 AI500576 BF477735 AI032569 AI972899 AI985583 Z28771 AI363829 AI693030 AA603586 BE773488 AW339301 BE773489 BE773462 BE773495 AI650338 BE773499 AI745717 BE811475 BE811470 BE811464 BE811418 BE811415 BE811400 BE811398 BE811388 BE811352 BE773501 BE773494 BE773486 BE773474 BE773473 BE773470 BE773461 BE811350 BE811337 BF593847 BG055071 AW675302 BF003068 AA719173 BE811348 AI582462 AI686240 BE773500 AI244845 AI565439 AI918453 AI472527 AI446740 AA035576 AA191414 AW674145 C05782 AI589264 D57558 AI468237 AI432033 AA989662 R21752 BF002457 AA988297 AL574095 AL576200 AL571074 AL574525 AL578810 BG498381 AI928364 BE879732 AA479834 AA479712 C17732 BM091258 BF843901 AW820230 C17476 BE327120 AA129574 AA136645 BF843900 AW806193 AA502832 AA649494 AL568520 AL547960 BE706937 BE811360 BE773498 BE811401 BE773484 BE811437 BE811380 BE811399 BF997171 BF757734 BE926037 AI377596 C06111 AW088968 BE811404 BE811472 AI865912 AI925607 AI871950 AI093510 BE905927 BE811435 AA191387 AW772000 BE811453 BE614379 BF844522 BI044896 AI744233 AW984527 C17504 BF843883 AI248307 BE773483 AI567995 W60075 BF941183 AI738844 BE811458 BE773481 AI262930 AA948565 BE706942 BE156360 T65026 AW242958 AW197954 BE905184 AA722206 AI344943 AI348877 AI334860 BE621857 BE156280 AA454099 AA037722 BF843897 AW806183 AA043216 BG482896 AA182734 AA877242 AW372926 H27252 R38114 BF851858 BE156214 AA190427 T91762 AA035067 AA837326 T10930 BF906587 BI755027 BG506731 BC008442 BC010166 AL550134 AL553096 AL548700 AL550751 AL547978 AL545286 AL540643 AU118627 AL601379 BI259821 BG741786 BI868522 AU135866 BI552770 BI259210 BI256520 BI255569 BG485098 BI258228 BG498501 BM044512 AU133984 AL556586 BE745111 BI222633 AU133917 BG288151 BI260715 BI550550 BG500773 BI551761 BG707601 BI818593 BF691383 BG721129 BG541578 BE906666 BG751098 BI224135 BG400746 BG478065 BE790436 AW080238 AU137549 BG429896 BE392486 AW961686 BG721056 BE908365 BE546656 BG541235 AW583735 BG528290 BI260895 AW651691 BM048974 BM043805 BG142185 AA315188 AI446615 C06300 BG497644 AA088544 AI815987 BG528631 BE619182 AW239185AW062910AW062902AA347236 F11933 AA488005 AA301631 AA376800 D56120 AA343532 AA308636 F00242 AA376086 AA316968 AA343799 BI870221 BE910282 BG538748 AW960564 AV732879 D16854 AA192519 BF922148 AA216013 BG624091 BE544387 BG507008 AW176446 BF790033 BE088925 BE088854 AA921353 R21800 AA011222 T97525
442506 29197_1 NM.002640 L40377 BG227962 AI925897 W60100 BG980023 AA853496 AA360401 AW956168 W61361 AI074846 AA373798 BG193973 BG499418 BF816267 AI675932 BG611734 BG777123 AW449485 BF912016 BE566411 BM068728 AW976385 AL121194 AI767324 BM054718 AW366882
436772 1239464.' AA156151 Z25109 C05177 AW975688 AA731063 N67084 434596 14701.1 AF147374 T59538 T59589 T59598 T59542 412564 18571.1 X83703 NM_014391 BC018667 AU139209 BE924924 BE924899 BE924977 BE924985 BE924947 BF229055 BE924917 BE924938 BE812621 BE924937 AA969184 BE924898 BF229066 BF229054 BF081177 BE924934 BF229040 BE925037 BE925011 BG943776 AA488072 AA486364 Z36249 AW455806 AW582753 BF081131 BE924910 BF229058 BF081172 BE924956 AW378093 BF081132 BF081168 BE812736 BE812738 BF081165 C04160 C04483 BF229048
442006 1239046.1 AW975183 AA973583 AI365103 AI699495 AI301787
TABLE 69C
Pkey. Unique number corresponding to an Eos probeset
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham, et al." refers to the publication entitled "The DNA sequence of human chromoεome 22" Dunham, et al. (1999) Nature 402:489495.
Strand: Indicates DNA strand from which exons were predicted.
NLposition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand NLpoεitioπ
402463 9796896 Minus 8818-8952
400494 9714719 Plus 169845-170272
401234 9929642 Plus 120173-120337
406506 7711374 Minus 6843-8077
405025 7107727 Plus 105267-105343,106184-106294,106387-10653
405121 8102330 Minus 35816-36004,36587-36684
400666 8118496 Plus 17982-18115,20297-20456
TABLE 70A:
Pkey: Unique Eoε probeset identifier number
ExAccn: Exemplar Acceεsion number, Genbank xceεsion number UnigenelD: Unigene number Unigene Title: Unigene gene title R1 : Ratio of the mean of the vesεel Al's to the mean of the HUVEC Al's
Pkey ExAccn UnigenelD Unigene Title R1
428928 BE409838 Hε.194657 cadherin 1, type 1, E-cadherin (epitheli 0.99
439180 AI393742 Hs.199067 v-erb-b2 avian erythroblastic leukemia v 1.06
412636 NM 004415 desmoplakiπ (DPI, DPII) 1.25
426158 NM.001982 Hs.199067 v-erb-b2 avian erythroblastic leukemia v 1.36
414320 U13616 Hs.75893 aπkyrin 3, node of Ranvier (ankyrin G) 1.50
417878 U90916 Hs.82845 Homo sapiens cDNA: FLJ21930 fis, clone H 1.55
414572 AU077174 Hs.288181 cathepsin H 1.64
415314 N88802 Hs.5422 glycoprotein M6B 1.70
431103 M57399 Hε.44 pleiotraphin (heparin binding growth fx 1.75
406973 M34996 Hε.198253 major histxompatibility complex, class 1.88
456974 M12529 Hs.169401 apolipoprotein E 1.90
430560 Z28942 Hs.243960 N-myc downstream-regulated gene 2 1.91
406828 AA419202 Hε.84298 CD74 antigen (invariant polypeptide of m 1.97
422048 NM 012445 Hs.288126 εpoπdin 2, extrxellular matrix protein 1.99 406826 AW516005 Hs.84298 CD74 antigen (invariant polypeptide of m 2.02
453023 AW028733 Hs.31439 serine protease inhibitor, Kunitz type, 2.03
413391 AI223328 Hε.75335 glycine amidinotransferase (L-arginine:g 2.12
406824 AW515961 Hε.84298 CD74 antigen (invariant polypeptide of m 2.15
418299 AA279530 Hε.83968 integnn, beta 2 (antigen CD18 (p95), ly 2.17
437536 X91221 Hs.144465 ESTs 2.21
442402 NM 000954 Hs.8272 prostaglandin D2 synthaεe (21 kD, brain) 2.26
446945 AI193115 Hs.16611 tumor protein D52-like 1 2.27
422639 AI929377 Hs.173724 creatiπe kinase, brain 2.29
427451 AI690916 Hε.178137 transducer of ERBB2. 1 2.31
454042 H22570 hypothetical protein FLJ20093 2.37
418283 S79895 Hε.83942 cathepsin K (pycnodysoεtoεiε) 2.38
424247 X14008 Hs.234734 lysozyme (renal amyloidosis) 2.39
422103 AA984330 Hs.111676 protein kinase H11; small stress protein 2.41
415994 NM.002923 Hs.78944 regulator of G-protein signalling 2, 24k 2.43
427393 AB029018 Hε.177635 KIAA1095 protein 2.47
414217 AI309298 Hε.279898 Homo sapieπε cDNA: FLJ23165 fiε, clone L 2.49
414063 H26904 Hs.75736 apolipoprotein D 2.50
426716 NM.006379 Hs.171921 sema domain, immunoglobulin domain (Ig), 2.51
414803 X03100 Hε.914 Human mRNA for SB clasεll hiεt ompatibi 2.51
410532 T53088 Hs.155376 hemoglobin, beta 2.56
431369 BE184455 Hs.251754 εxretory leukxyte proteaεe inhibitor ( 2.58
437952 D63209 Hε.5944 εolute earner family 11 (proton-coupled 2.58
453655 AW960427 Hs.342874 transforming growth fxtor, beta rxepto 2.59
453655 AW960427 Hs.342874 transforming growth fxtor, beta rxepto 2.59
453655 AW960427 Hs.342874 transforming growth fxtor, beta recepto 2.59
427980 AA418305 Hs.303205 EST 2.59
442695 AC002425 Hs.8603 p8 protein (candidate of metastaεiε 1) 2.62
425751 T19239 Hs.1940 cryεtallin, alpha B 2.63
414194 BE175494 Hs.75811 N-xylεphiπgosine amidohydrolase (xid c 2.63
443907 AU076484 Hs.9963 TYRO protein tyrosine kinase binding pro 2.66
453464 AI884911 Hs.32989 rxeptor (calcitonin) xfivity modifying 2.67
410677 NM 003278 Hε.65424 tetranxfin (plasmiπogen-binding protein 2.67
452685 AI634651 Hε.30250 v-maf musculoaponeurotic fibroεarcoma (a 2.67
425869 AA524547 Hs.160318 FXYD domain-containing ion traπεport reg 2.73
406643 N77976 Hs.347939 hemoglobin, alpha 2 2.73
453767 AB011792 Hs.35094 extrxellular matrix protein 2, female o 2.74
424614 X54486 Hs.151242 serine (or cysteine) proteinase inhibito 2.80
444195 AB002351 Hε.10587 KIAA0353 protein 2.81
417233 W25005 Hε.24395 small inducible cytokine subfamily B (Cy 2.86
442498 U54617 Hs.8364 Homo sapienε pyruvate dehydrogenaεe kina 2.92
412810 M21574 Hs.74615 platelet-derived growth fxtor rxeptor, 2.93
440820 AL031846 plakophilin 4 2.94
429123 AB011099 Hs.196647 KIAA0527 protein 2.97
411529 AA430348 Hs.317596 Homo εapienε cDNA FU12927 fiε, clone NT 3.01
413305 NM 000426 Hs.323511 Homo sapiens cDNA: FU23176 fis, clone L 3.01
425622 AW360847 Hs.16578 ESTs 3.01
420195 N44348 Hs.251385 Homo sapienε cDNA FU11177 fis, clone PL 3.04
446584 U53445 Hε.15432 downregulated in ovarian cancer 1 3.04
407869 AI827976 Hs.24391 hypothetical protein FU13612 3.06
423915 AF039018 Hs.135281 alpha-xtinin-2-asεxiated LIM protein 3.07
410036 R57171 Hs.57975 calεequeεtrin 2 (cardix muεcle) 3.10
412047 AA934589 Hs.49696 ESTε 3.12
414840 R27319 Hs.23823 hairy/enhancer-of-εplit related with YRP 3.14
424651 AI493206 ESTs 3.17
443932 AW888222 Hε.9973 tensin 3.18
420859 AW468397 Hs.100000 S100 calcium-binding protein A8 (calgran 3.20
434025 AF114264 Hs.216381 Homo εapieπε clone HH409 unknown mRNA 3.20
421834 BE543205 Hε.288771 DKFZP586A0522 protein 3.20
423961 D13666 Hs.136348 perioεtiπ(OSF-2os) 3.24
447384 AI377221 Hs.40528 ESTs 3.24
425383 D83407 Hε.156007 Down syndrome critical region gene 1-lik 3.25
447023 AA356764 Hε.17109 integral membrane protein 2A 3.25
420136 AW801090 Hs.195851 xtin, alpha 2, smooth muscle, aorta 3.25
406972 M32053 gb-.Human H19 RNA gene, complete eds. 3.26
410132 NM.003480 Hs.300946 Microfibril-ass∞iated glycoprotein-2 3.27
430998 AF128847 Hε.204038 indolethylamine N-methyltransferase 3.28
456898 NM.001928 Hε.155597 D component of complement (adipsin) 3.29
443623 AA345519 Hε.9641 complement component 1, q subcomponent, 3.33
410614 AI091195 Hε.65029 growth arrest-εpxific 1 3.35
451529 AI917901 Hs.208641 ESTs 3.35
430310 U60115 Hs.239069 four and a half LIM domains 1 3.37
424897 D63216 Hs.153684 fnzzled-related protein 3.37
427111 AA351026 Hs.173594 serine (or cysteine) proteinase inhibito 3.38
443604 C03577 Hs.9615 myosin regulatory light chain 2, smooth 3.41
421913 AI934365 Hs.109439 osteoglycin (osteoinducfive fxtor, mime 3.43
451331 AK002039 Hs.251385 Homo εapienε cDNA FLJ 11177 fiε, clone PL 3.44
416908 AA333990 Hs.80424 ∞agulation fxtor XIII, A1 polypeptide 3.46
407938 AA905097 Hs.85050 phospholambaπ 3.48
418005 AH 86220 Hs.83164 collagen, type XV, alpha 1 3.51
452877 AI250789 Hs.32478 ESTs 3.52
419577 L36531 Hε.91296 integnn, alpha 8 3.52
404277 NM.019111*:Homo sapiens major histxompa 3.54 407815 AW373860 Hs.183860 hypothetical protein FU20277 3.58
421853 AL117472 Hs.108924 SH3-domain protein 5 (ponεin) 3.64
447111 AI017574 Hs.17409 cyεteiπe-rich protein 1 (intestinal) 3.68
426935 NM_000088 Hs.172928 collagen, type I, alpha 1 3.70
418371 M13560 Hε.84298 CD74 antigen (invariant polypeptide of m 3.71
440274 R24595 Hs.7122 scrapie responεive protein 1 3.73
427818 AW511222 Hs.193765 ESTε 3.73
433465 AV657778 Hs.3314 selenoprotein P, plasma, 1 3.75
458568 AI769067 Hs.127824 ESTs, Weakly εimilar to T28770 hypotheti 3.77
459290 NM 001546 Hs.34853 inhibitor of DNA binding 4, dominant neg 3.80
424206 NM 003734 Hs.198241 amine oxidase, copper containing 3 (vase 3.83
453874 AW591783 Hs.36131 collagen, type XIV, alpha 1 (unduliπ) 3.86
428957 NM 003881 Hs.194679 WNT1 inducible signaling pathway protein 3.89
434868 R50032 Hs.159263 collagen, type VI, alpha 2 3.90
417043 NM 004369 Hε.80988 collagen, type VI, alpha 3 3.95
417512 X76534 Hs.82226 glycoprotein (tranεmembrane) nmb 3.95
452669 AA216363 Hs.262958 hypothetical protein DKFZp434B044 3.97
421314 BE440002 Hs.180324 Homo εapienε, clone IMAGE4183312, mRNA, 4.01
449925 AI342493 Hs.24192 Homo εapienε cDNA FU20767 fis, clone CO 4.03
453500 A1478427 Hs.43125 esophageal cancer related gene 4 protein 4.07
430572 U33114 Hs.245188 tissue inhibitor of metalloproteinase 3 4.09
421823 N40850 Hs.28625 ESTs 4.17
422550 BE297626 Hε.296049 microfibrillar-asεxiated protein 4 4.25
443060 D78874 Hs.8944 procollagen C-endopeptidaεe enhancer 2 4.26
450912 AW939251 Hs.25647 v-foε FBJ murine osteosarcoma viral oπco 4.29
432306 Y18207 Hs.303090 protein phosphatase 1, regulatory (inhib 4.34
419938 AU076772 Hε.1279 ∞mplement component 1, r subcomponent 4.37
415165 AW887604 Hs.78065 complement component 7 4.37
414176 BE140638 Hs.75794 endothelial differentiation, lysophospha 4.41
452114 N22687 Hε.8236 ESTs 4.43
406850 AI624300 Hs.172928 collagen, type I, alpha 1 4.43
428411 AW291464 Hs.10338 ESTs 4.48
412802 U41518 Hs.74602 aquaporin 1 (channel-forming integral pr 4.51
406849 AA454809 Hs.172928 collagen, type I, alpha 1 4.54
453064 R40334 Hε.89463 potaεsium large conductance calcium-xti 4.57
429500 X78565 Hs.289114 hexabrachion (tenaεcin C, cytotxtin) 4.57
433336 AF017986 Hs.31386 εxreted frizzled-related protein 2 4.68
421814 L12350 Hs.108623 thromboεpondin 2 4.73
427373 AB007972 Hs.130760 yoεin phoεphatase, target subunit 2 4.76
414290 AI568801 Hs.71721 ESTs 4.98
415274 AF001548 Hε.78344 myosin, heavy polypeptide 11, smooth mus 5.13
417130 AW276858 Hε.81256 S100 calcium-binding protein A4 (calcium 5.14
416784 AA334592 Hs.79914 lumican 5.20
453355 AW295374 Hε.31412 Homo sapienε cDNA FU11422 fis, clone HE 5.50
408221 AA912183 Hs.47447 ESTs 5.65
430223 NM 002514 Hs.235935 nephroblastoma overexpressed gene 5.87
416585 X54162 Hε.79386 leiomodin 1 (smooth muscle) 6.47
422737 M26939 Hε.119571 collagen, type III, alpha 1 (Ehlers-Danl 6.65
426406 A1742501 Hε.169756 ∞mplement ∞mponent l. s subcomponent 7.94
448429 D17408 Hs.21223 calponin 1, basic, smooth muscle 9.90
413624 BE177019 Hs.75445 SPARC-like 1 (mastθ, hevin) 9.91
TABLE 70B
P Pkkeeyy:: Unique Eos probeεet identifier number
CCAATT nnuummbbeerr.. Gene cluster number
Axesεion: Genbank a∞eεεion numbers
Pkey CAT Number A∞esεion
412636 1438.1 M77830 NM.004415 AF139065 BG681115 BG740377 BI712964 BG000656 AA128470 BI438324 H27408 BE931630 BE167165 AW370827
AW370813J05211 BG698865 BG740734 BG680618 BG739778 BI765807 BM353403 BM353248AW177784AW205789 AW951576AW848592 BE182164 BF149266 BE940187 BI060445 BI060444 BF350983 BE720095 BE720069 BE715154 BE082584 BE082576 BE004047 AA857316 BI039774 BE713818 BE713548 AW170253 BE160433 BI039775 AW886475 BM462504 BE931734 BF149264 AA340777 BF381183 BG621737 AU127260 AW364859 BF993352 BG223489 BE819009 BF381184 BE715956 R58704 AA852212 AW366566 BI090358 BF087707 BE819046 BE819005 AA377127 BE073467 BE819069 BE819048 BI036306 BG990973 BI040954 BF919911 AU140155 AI951766 AI434518 AW804674 BF752969 BE837009 BE925826 BF149265 AW995615 BE814264 BI039782 AU140407 BE144243 BE709863 BF985642 BE001923 BF933510 AW265328 BG436319 BE182166 AW365175 AW847688 BE818280 AW177933 BF873679 AW178000 BE082526 BF476866 BF086994 BF592276 BE082507 BE082514 BE082505 BF873693 AW068840 AW847678 BF804153 AW365157 BE813930 BE002030 AW365153 BE184941 BF749421 BE184920 BF839562 BE184933 BF842254 BE698470 BE931048 BF999889 BF368816 BE184924 BE159646 BE714632 BE184948 BG986845 AA131128 AA099891 W39488 C04715 BF096124 BE865341 AW799304 AL603116 BE149760 BE705967 BE705966 BE705968 AW848723 AW376699AW376817AW376697BG005097 BF751115BE696084AW848371 AW376782AW848789AW849074AW361413 BF927725 BF094211 AW997139 BE865474 BE185187 BE156621 BE715089 BE713297 BE713298 BE179915 AW799309 BF872345 BF088676 BE705939 AW752599 BG005197 BF350086 BE715196 BE715155 BF752396 BF093817 BF831190 BF752409 BE006561 BG959922 BF094833 BF094748 BF094583 AW377699AW607238 BE082519AW377700 BF349467AI190590 AI554403AI392926 AU158477 BI467252AU159919 AI760816 BF082516 AI439101 AA451923 AI340326 AI590975 BI791553 AI700963 AI142882 AA039975 AA946936 AA644381 BM314884 AA702424 AI417612 AW190555 AI220573 AI304772 AI270345 AI627383 AA552300 AI911702 AW166807 AI346078 W95070 AA149191 AA026864 AI830049 AW780435 AI078449 AI819984 AI858282 BI468588 AI860584 AI025932 AA026047 AA703232 AA658154 AA515500 AW192085 AA918281 T77861 AI927207 AI205263 BF082491 AW021347 AI568096 BE939862 AA088866 D12062 AA056527 AA782109 W19287 W02156 AW150038 AA022701 T87181 H44405 AI910434 BF082513 AI494069 AI270027 AI635878 AA128330 BG681425 BE706078 R20904 BG680059 BG676647 BF764409 AA026654 AV745530 BI762796 BG287391 AW798780 BE706045 BE926470AW799118 BF087996 BE002273 AW879451 AI571075 BE067786AV721320 AI022862 N29754 C03378 N84767 AA131077 H30146 BE714290 AI686869 AI568892 AI915596 AW105614 AI887258 AI538577 BE926474 BE067737 BG319486 AA247685 AW798883 AW103521 BF989173 AW860878 BE939707 BE185750 BE714064 BE713903 BE713868 BE713763 BG950164 BE713810 AW365151 BG955489 BE005272 BF915937 AW365148 AI905927 BF992780 AW853812 BG954443 BI770853 BG679406 BG740832 BG681087 BG698430 AA455100T87267 BE696209 BE696210 BI089483 BE006273 BE872225 AW391912 BE925515 BG677012 BG741970 AA026480 BE705999 BG677157 BE009090 BG681378 BE712291 BG961498 BG678984 BI040941 AA337270 AW384371 AW847442 BI058659 BE813665 W95048 W25458 AW177786 AA025851 BE931733 BF154837 BG949393 BE714441 AW996245 BE711801 AI284090 BE064323 BE719390 BE940148 BG991212 BF375714 BF349522 BG996267 T48793 BI013292 BE001925 AW365156 AW365154 AW606653 BF763109 BE931637 BE167181 BE713879 BF354008 BF678726 H90899 AW365145 W38382 AI498487
454042 30254 1 AJ420458 AI018523 AA708686 BF949633 AL119553 BF945960 AI081305 AA041432 AI921013 AI684910 AI654847 AW874199 AI206120
AW241428 R43035T66767 AW103715 W28478 BF953052 H45926 BF807568 AW903943 BE170143 BI040435 BF931989 BI600000 AV722350 W27787 H45331 BI549761 R53955 BI549855 BG991583 BI491075 AW020049 AW129293 H45263 AA410309 AA340613 R42410 AA707199 AI431587 BE858679 AW292267 AI421678 AA041195 BE466753 AI243913 AI358894 AW137298 AI366468 N64350 AA779107 AW025969 R49056 AA347011 R55722 A 771106 F04969 Z38381 F01659 H17396 BI493714 A1880103 AW771447 AI202561 AA788851 AI494436 BF856114 H22570
440820 3091 1 AW964381 BG007409 BM314056 AA465642T30661 T33111 Z42834 C04542 BF948152 BF944325 BF858895 AA935284 AI267360 N64249
W67500 F07962 AA322394 BI489987 BE644965 BM313782 AA910364 AI809246 AA836750 BF115228 AA829730 N27413 BM141766 AI742325 AA455261 AA938708 AI420241 AI130039 BF222341 BF941301 AA771807 Z41034 BF447457 BF447426 AW515347 T03874 F02360 F02302 N34898 AI678586 AA807824 AA948556 AW204638 BM142045 BF446775 AV648364 AI801368 AA971739 AI017351 AA760722 AI460007 AI458383 AI694152 AA226536 BE467282 N47808 BE348825 BE830581 BE830583 N53009 N59351 N41056 W67501 AA016246 H43293 F21282 R59121
R56280 424651 46029.5 BG435302 BM083687 AA904035 AA488889 W76175 AA761874 H28767 AA910081 AA837086 AI521825 BG986378 AI478562 AA743152 AA746092
H88863 BG986375 AA635644 AI493206 AA669979 BE245127 BG986430 BG986529 BF665873 BG030157 BG622575 AA766495 TABLE 70C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunham, et al (1999) Nature 402489495
Strand Indicates DNA strand from which exons were predicted NLposition Indicates nucleotide poεifions of predicted exons
Pkey Ref Strand NLposition 404277 1834458 Minus 91665-91946
TABLE 71 A 774 GENES UP-REGULATED IN EWING SARCOMA COMPARED TO NORMAL ADULT TISSUES
Table 1 A lists 774 genes up-regulated in Ewing Sarcoma compared to normal adult fissues These were selxted from 35371 probesets on the Affymetπx/Eos Hu03 GeneChip array such that the ratio of "average" Ewing Sarcoma to "average" normal adult fissues was greater than or equal to 2 1 The "average" Ewing Sarcoma level was set to the 75th percentile amongst numerous Ewing εarcomas The "average" normal adult tissue level was set to the 85th percentile amongεt vaπouε non malignant tiεεueε In order to remove gene-spxific bxkground levels of non spxific hybndization, the 10th percenfile value amongεt the non malignant tiεεueε waε subtrxted from both the numerator and the denominator before the ratio was evaluated
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank xcesεioπ number
UnigenelD Unigene number
Unigene Title Unigene gene title
R1 75th percenfile of ewing εarcoma to 85th percentile of body map
Pkey ExAccn UπigeπeiD Unigene Title R1
104659 AW969769 Hε 105201 ESTε 703
101447 M21305 gb Human alpha satellite and satellite 3 647
105782 H09748 Hε 57987 B-∞ll CLL/lymphoma 11 B (zinc finger pro 505
115881 NM 005756 Hε 184942 G protein-∞upled rxeptor 64 488
121792 AW969726 Hε 98381 ESTs, Weakly similar to seπne protease 467
101104 AW862258 Hε 169266 neuropeptide Y rxeptor Y1 466
110278 AF061573 Hε 19492 protocadhenn 8 461
126645 AA316181 Hs 61635 six transmembrane epithelial antigen of 41 4
116752 AL008583 Hs 91622 neuronal pentraxm rxeptor 409
119717 AA918317 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger pro 396
104691 U29690 Hs 37744 Homo sapiens beta-1 adrenergic receptor 369
110728 AA737106 Hs 32250 ESTs, Moderately similar to I78885 seπn 355
121362 AF050147 Hs 97932 chondromodulin I prxursor 347
131291 NM.004350 Hs 170019 runt related transcnption fxtor 3 330
101063 D54745 Hs 80247 cholxystokmin 31 7
121619 AA528339 Hs 178062 ESTs, Weakly similar to phosphafidylεeπ 287
122651 AW975398 Hs 293836 ESTε 280
100299 D49493 Hs 2171 growth differentiation fxtor 10 265
129977 NM.000399 Hs 1395 early growth reεponεe 2 (Krox-20 (Drosop 262
123619 AA602964 gb no97c02 s1 NCI_CGAP_Pr2 Homo sapiens 261
124006 AI147155 Hs 279727 ESTs, homologue of PEM-3 [Ciona savignyi 231
116301 AW969706 Hs 293332 ESTs 226
121231 AA814948 Hs 96343 ESTε, Weakly similarto ALUC HUMAN »« 223
106533 AL134708 Hs 145998 ESTs 223
109166 AA219691 Hs 73625 RAB6 interxting, kineεm like (rabkmeε 21 3
131313 R96290 Hs 75874 πbosomal protein L44 208
116790 AW161357 microtubule-assxiated protein tau 187
105316 AI671245 Hs 24835 hypothetical protein FU14594 182
102123 NM_001809 Hs 1594 centromere protein A (17kD) 178
126218 AL049801 Hs 13649 Novel human gene mapping to chomoso e 13 178
119791 AA554907 Hs 58291 ESTε 167
113003 AW292315 Hs 7215 ESTs 163
102836 U94320 Hs 158330 neuropeptide Y rxeptor Y5 163
126799 AW753865 Hε 74376 olfxtomedin related ER Ixalized protei 163
105298 BE387790 Hε 26369 hypothetical protein FU20287 155
107160 AA314490 Hε 27669 KIAA1563 protein 148
115313 AA808001 Hε 184411 albumin 146
123308 C14187 Hε 103538 ESTs 142 126077 M78772 Hs 210836 ESTs 140
100698 AA884407 Hs 211595 protein tyroεine phosphatase, non recept 139
106821 NM 006594 Hs 28298 adaptor-related protein complex 4, beta 139
110288 H40665 Hs 31564 ESTs 138
106498 AI221919 hypothetical protein FU10582 138
112134 R41823 Hs 7413 ESTs.calsyntenin 2 137
115265 AA334274 Hs 18368 DKFZP564B0769 protein 134
128639 AW582962 Hs 102897 CGI 47 protein 132
125698 AF078847 Hs 191356 general transcnption fxtor HH polype 128
105200 AA328102 Hs 24641 cytoskeleton assxiated protein 2 123
119456 AA248897 Hs 48784 ESTs 122
135155 AI207958 Hs 166556 Homo εapienε, Similar to TEA domain fami 121
106614 AA648459 Hs 335951 hypothetical protein AF301222 120
131941 BE252983 Hs 35086 ubiquitin specific protease 1 120
132968 AF234532 Hs 61638 myosin X 11 7
132725 NM 006276 Hs 184167 splicing fxtor, arginine/seπne-πch 7 11 7
111353 W20090 Hs 6616 ESTs 11 4
123289 AA495904 Hs 103316 ESTs 11 3
104968 AI249502 Hs 29669 ESTs 11 1
123532 AA608733 gb ae56f06 s1 Stratagene lung carcinoma 11 0
104173 AA084273 Hs 76561 ESTs, Weakly similar to S47072 finger pr 107
125556 AB033064 Hε 236463 KIAA1238 protein 107
127240 AJ005683 Hε 86998 nuclear fxtor of activated T-cells 5 t 106
123049 BE047680 Hε 211869 diekkopf (Xenopus laevis) homolog 2 106
132315 AF091086 Hs 44563 hypothetical protein 105
134321 BE538082 Hs 8172 ESTs, Moderately similar to A46010 X-fin 105
128609 NM.003616 Hε 102456 survival of motor neuron protein interx 104
131945 NM 002916 Hε 35120 replication factor C (xtivator 1) 4 (37 104
110730 N67655 Hε 26411 ESTs 103
119186 AI979147 Hε 101265 hypothetical protein FU22593 103
115909 AW872527 Hs 59761 ESTs, Weakly similar to DAP1 HUMAN DEATH 103
121916 AW117207 Hs 98523 ESTs 10 2
131402 Y08890 Hs 113503 karyophenn (importin) beta 3 101
101879 AA176374 Hs 243886 nuclear autoantigenic sperm protein (his 100
133181 X91662 Hs 66744 twist (Drosophila) homolog (xro∞phalos 100
131307 NM 000025 Hs 2549 adrenergic, beta-3-, rxeptor 100
113849 AA457211 Hs 8858 bromodomain adjacent to zinc finger doma 99
103446 X98834 Hs 79971 εal (Drosophila) like 2 97
105091 AA148859 Hs 179909 hypothetical protein FU22995 96
106146 W07288 Hε 118392 ESTs, Weakly similar to LNHUER IgE Fc re 95
127003 AW816515 Hs 173540 ATPase, Clasε V, type 10D 95
115414 AA662240 Hs 283099 AF15q14 protein 94
117829 BE160952 Hs 247117 ESTs, Moderately similar to ALUF.HUMAN I 94
126098 M79088 gb EST01236 Subtrxted Hipp∞ampus, Stra 93
121910 AI204600 Hs 96978 hypothetical protein MGC10764 92
130625 AF176012 Hs 260720 J domain containing protein 1 92
129755 R42216 Hs7759 Homo εapiena clone 24538 mRNA sequence 91
100335 AW247529 Hs 6793 platelet-xfivating fxtor xetylhydrola 90
111109 AI940675 Hs 20914 hypothetical protein FU23056 90
120217 AA862257 Hs 66035 ESTs 90
112891 T03927 Hs 293147 ESTs, Moderately similar to A46010 X lin 89
131601 NM.007115 Hs 29352 tumor nxrosiε fxtor, alpha-induced pro 88
126262 AI085153 Hs 143764 ESTε, Weakly similar to unknown [H sapie 88
113903 AI368034 Hs 36679 ESTs, Weakly similar to A46010 X-lmked 87
105253 AW997484 Hε 5003 KIAA0456 protein 86
102581 AU077228 Hε 77256 enhancer of zeste (Drosophila) homolog 2 86
105172 AA187554 Hs 300496 mitxhondπal solute earner 86
100380 D82343 Hs 74376 neurablastoma (nerve tiεεue) protein 86
129229 AF013758 Hε 109643 polyadenylate binding protein iπterxhn 85
102725 AB026187 Hε 159156 protocadhenn 11 85
130298 AI347487 Hε 132781 class I cytokine rxeptor 84
132294 AB023191 Hε 44131 KIAA0974 protein 82
118644 AA443241 πbosomal protein L44 82
106575 AW970602 Hs 105421 ESTs 82
133142 AW952412 Hs 65874 ESTs, Weakly similar to A40348 Elav/Sex- 81
119499 AI918906 Hε 55080 ESTε 81
100248 NM.015156 Hs 78398 KIAA0071 protein 81
114837 BE244930 Hs 166895 ESTε 80
107098 AI823593 Hs 27688 ESTε 80
123960 AW082862 Hs 287733 hypothetical protein FU23189 79
105280 AA894638 Hε 14600 ESTs 79
115147 AA745781 Hs 38399 hypothetical protein MGC2454 79
134570 U66615 Hs 172280 SWI/SNF related, matnx asεxiated, xti 79
133063 AI654133 Hs 30212 thyroid receptor interxting protein 15 78
105730 AW377314 Hε 5364 DKFZP564I052 protein 78
126426 AA125984 gb zn27h06 Sfratagene neuroepithelium 78
107254 Z45998 Hε 22543 Homo εapienε mRNA, cDNA DKFZp761H912 (f 78
134367 AA339449 Hs 82285 phoεphoπboεylglycmamide formyltranεfer 78
119082 AF252297 Hs 91546 cytxhrome P450 refinoid metabolizing pr 77
125400 AL110151 Hs 128797 DKFZP586D0824 protein 77
129413 AW377610 Hs 11123 DKFZP564G092 protein 77
116766 AI608657 Hs 95097 ESTε 77
129075 BE250162 Hs 83765 dihydrofolate reductaεe 76 105143 AI368836 Hs 24808 ESTs, Weakly similar to I38022 hypotheti 76
132438 AW363687 Hs 82916 chaperonin containing TCP1, subunit 6A ( 76
118036 AI471862 Hs 196008 Homo sapiens cDNA FU11723 fis, clone HE 76
131170 NM 014253 odz (odd Oz/ten m, Drosophila) homolog 1 75
104548 R39398 Hs 91559 ESTs 75
131495 AA812434 SMC2 (structural maintenance of chromoso 75
132543 BE568452 Hs 344037 protein regulator of cytokinesis 1 74
124040 U23752 Hs 32964 SRY (sex determining region Y) box 11 74
127695 AA714731 Hs 291457 ESTs, Weakly similar to heterogeneous n 73
132559 AF119848 Hs 270863 hypothetical protein PR01580 73
101050 AU077324 Hs 1832 neuropeptide Y 72
111823 R35252 Hs 130558 ESTs Weakly similar to 2109260A B cell 72
116401 AW893940 Hs 59698 ESTs 71
105127 AA045648 Hs 301957 nudix (nucleoside diphoεphate linked moi 7 1
128478 AA708205 Hs 100343 ESTε 1
110456 H52348 Hs 36636 ESTε 71
118846 AW299598 Hs 50895 homx box C4 7 1
120934 AA226198 gb πc26a07 ε1 NCI_CGAP_Pr1 Homo εapieπε 71
128132 AA225632 gb nc08a07 r1 NCI_CGAP_Pr1 Homo sapiens 70
127431 AW771958 Hs 175437 ESTs, Moderately similar to PC4259 fem 70
106157 W37943 Hs 34892 KIAA1323 protein 69
117852 AW877787 Hs 136102 KIAA0853 protein 69
106213 N45018 Hs 8769 hypothetical protein DKFZp761J17121 69
118013 A1674126 Hs 94031 ESTs 69
120147 AI917116 hemoglobin, beta 68
118267 N34905 Hs 44653 Homo εapiens cDNA FU22669 fiε, clone H 68
132581 AK000631 Hs 52256 hypothetical protein FLJ20624 68
120325 AA195651 AP-2 beta traπεcπption fxtor 68
133276 AW978439 Hs 69504 ESTε 68
127742 AW293496 Hs 180138 ESTs 67
127664 AA806164 Hs 116502 ESTs 67
108778 AF133123 Hs 90847 general tranεcπpfion fxtor IIIC, polyp 66
121553 AA412488 Hs 48820 TATA box binding protein (TBP) ass∞iate 66
107059 BE614410 Hs 23044 RAD51 (S cerevisiae) homolog (E coli Re 66
133658 AA319146 Hs 75426 secretogranin II (chromogranm C) 66
115197 R18656 ESTε 65
112268 W39609 Hε 22003 solute earner family 6 (neurotransmitte 65
103346 X87613 Hε 5464 thyroid hormone rxeptor coxtivatmg pr 64
126967 AA205976 gb zq48a10 r1 Stratagene hNT neuron (937 64
118499 N67274 Hε 50141 EST 64
105301 AW352357 Hs 7457 MAGE1 protein 63
113617 AI869372 Hs 17207 Homo sapienε cDN A FU 11922 fiε, clone HE 63
127968 AA830201 Hs 124347 ESTε 63
134719 AA852985 Hs 89232 chromobox homolog 5 (Drosophila HP1 alph 63
110748 AW581992 Hs 301434 KIAA1387 protein 63
115844 AI373062 Hs 332938 hypothetical protein MGC5370 63
121885 AA934883 Hs 98467 ESTs, Highly similar to AF2577371 cilia 62
102398 U42359 gb Human N33 protein form 1 (N33) gene, 62
130882 AA497044 Hs 20887 hypothetical protein FU10392 62
132256 AI078645 Hs431 munne leukemia viral (bmι-1) oncogene h 62
106383 AA447453 Hε 27860 Homo sapiens mRNA, cDNA DKFZp586M0723 (f 62
135186 U73328 Hs 172648 distal less homeobox 4 62
105510 Z42047 Hs 283978 Homo sapiens PR02751 mRNA, complete eds 62
109261 BE466639 Hs 61779 Homo sapiens cDNA FU13591 fis, clone PL 61
114357 R41677 Hs6107 Homo sapienε cDNA FU14839 fiε, clone OV 61
128501 AL133572 Hs 199009 protein containing CXXC domain 2 61
109747 AI223001 Hs 22969 ESTε, Weakly similar to Z141.HUMAN ZINC 61
128361 AW172570 Hs 14600 ESTε 61
115773 AW445044 Hs 38207 Human DNA sequence from clone RP4-530I15 60
104689 AA420450 Hs 292911 Plakophilin 60
113575 AW138168 Hs 15671 ESTs, Weakly εimilar to KBF3_HUMAN NUCLE 60
121830 AW394055 Hs 98427 ESTs, Weakly similar to I38022 hypotheti 59
119298 NM 01241 Hs 155478 cyclin T2 59
109841 H01052 gb yj32h01 s1 Soares placenta Nb2HP Homo 59
115622 AI088691 Hs 208414 Homo sapiens mRNA, cDNA DKFZp564D0472 (f 58
122969 AW821252 Hs 104336 hypothetical protein 58
109872 R65841 Hs 28653 ESTs 58
114208 AL049466 Hs7859 ESTs 58
113494 T91451 Hs 86538 ESTs 58
127684 AA668631 Hs 159971 KIAA0379 protein 58
129300 W94197 Hs 110165 nbosomal protein L26 homolog 58
127489 AA650250 Hs 272076 ESTs 58
133479 W01556 Hs 238797 ESTs, Moderately similar to I38022 hypot 58
105909 AA195191 hypothetical protein FU20729 58
101255 BE385864 Hs 149894 mitxhondπal translational initiation f 58
134676 W28051 Hs 87819 Homo sapienε, clone MGC 2492, mRNA, comp 57
130895 AA641767 Hs 21015 hypothetical protein DKFZp564L0864 simil 57
126395 AI468004 Hs 278956 hypothetical protein FU 12929 57
130723 BE247676 Hs 18442 E-1 enzyme 57
107230 AI034467 Hs 34650 ESTε 57
102745 AW753865 Hs 74376 olfxtomedin related ER Ixalized protei 56
108699 AA121514 Hs 70832 ESTε 56
128080 F12310 gb HSC38D041 normalized infant brain cDN 56 117357 N24829 gb yx98h12 s1 Soareε melanxyte 2NbHM Ho 56
120827 AA382525 Hs 132967 Human EST clone 122887 manner franεpoεo 56
123494 AW179019 Hs 112110 mitxhondπal πbosomal protein L42 55
100438 AA013051 Hs 91417 topoisomerase (DNA) II binding protein 55
126165 AI741816 Hs 125897 ESTs 55
125934 AA193325 Hs 32646 hypothetical protein FLJ21901 55
124370 AI243499 Hs 170652 ESTε 55
106135 I AL117474 Hε 41181 Homo εapienε mRNA, cDNA DKFZp727C191 (fr 55
106668 R49390 Hε 254129 KIAA1678 54
132967 AA316181 Hε 61635 εix transmembrane epithelial antigen of 54
109606 Z43371 Hε 7012 ESTs 54
115816 BE042915 Hε 22572 Homo sapienε cDNA FU 13675 fis, clone PL 54
125186 AA610620 Hs 181165 major histxompatibility ∞mplex, class 54
131185 BE280074 Hs 23960 cyclin B1 54
111227 T06701 Hs 12268 ESTs 54
105516 AK001269 Hs 30738 hypothetical protein FLJ 10407 54
103409 NM 004454 Hs 43697 ets vaπant gene 5 (ets related molecule 54
116008 T79153 Hs 48589 zinc finger protein 228 53
106394 Z42993 Hs 25320 Homo sapiens clone 25142 mRNA sequence 53
115121 AI634549 Hs 325422 ESTs 53
125464 N71807 gb yz29d09 r1 Soares.mulfiple.sclerosis. 53
115596 AW298597 Hs 61884 Homo sapiens, clone IMAGE 4298026, mRNA, 53
119040 R02394 Hs 269436 ESTs, Moderately similar to PC4259 fern 53
128040 AW500486 Hs 180610 splicing fxtor prol e/glutamiπe πch ( 53
110151 H18835 Hs 31608 hypothetical protein FU20041 53
105539 AB040884 Hs 109694 KIAA1451 protein 52
130567 AA383092 Hs 1608 replication protein A3 (14kD) 52
111077 N41367 Hs 173002 ESTs, Weakly similar to I38022 hypotheti 52
120830 AI568170 Hs 96886 ESTs 52
106516 AL137311 Hs 234074 Homo εapieπs mRNA, cDNA DKFZp761G02121 ( 52
103316 X83301 Hs 324728 SMA5 52
116129 AF189011 Hs 49163 putative πbonuclease III 52
131253 R71802 Hs 24853 ESTs 52
116680 AW902848 Hs 273829 ESTs 52
123949 AA621665 Hs 208957 EST 52
105511 AB037829 Hs 3862 regulator of nonsense transcπptε 2, DKF 52
125847 AW161885 Hs 269745 ESTs 51
108301 AA069728 Hs 184582 πbosomal protein L24 5 1
110799 AI089660 Hs 323401 dpy-30-lιke protein 51
104899 AA054726 Hs 285574 ESTs 5 1
125972 AI927475 Hs 35406 ESTs Highly similarto unnamed protein 51
107869 AW975998 Hs 58595 ESTs, Weakly similar to 138022 hypotheti 51
121309 AA293834 Hs 97312 ESTs 51
125321 T86652 Hs 178294 ESTs 51
102627 AL021918 Hs 158174 zinc finger protein 184 (Kruppel-like) 51
104446 AF084555 Hs 7351 cyclic AMP phosphoprotein, 19 kD 50
126020 H79863 Hε 114243 ESTs 50
116814 H50834 Hε 77899 gbyp86a10 s1 Soares fetal liver spleen 50
130622 AI582291 Hs 16846 ESTs, Weakly similar to 04HUD1 debπsoqu 50
110818 AL157503 Hs 27552 Homo sapiens mRNA, cDNA DKFZp586N2424 (f 49
127765 AA971146 Hs 129074 ESTs, Moderately similarto MEG1 MOUSE M 49
108768 AF181721 Hs 61345 RU2S 49
120484 AA253170 Hs 96473 EST 49
114518 AW163267 Hs 106469 suppressor of varl (S cerevisiae) 3-lιke 49
129012 R81936 nbosomal protein L44 49
124973 A1476066 Hs 102243 ESTs, Weakly similar to I78885 seπne/th 49
124648 AA249086 Hs 125034 hypothetical protein FU13340 49
126904 AA948033 Hs 130853 ESTs 49
131526 AIO05169 Hε 28274 Homo sapienε cDNA FU22049 fis, clone H 49
130637 AA356764 Hs 17109 integral membrane protein 2A 48
126769 AA083456 gb zn09g08 r1 Stratagene hNT neuron (937 48
126086 H75681 gb yr77g01 r1 Soares fetal liver spleen 48
100169 AL037228 Hs 82043 D123 gene product 48
130262 D63216 Hs 153684 fnzzled-related protein 48
109260 AW978515 Hs 131915 KIAA0863 protein 48
103120 BE410731 Hs 74050 follicular lymphoma vanant transl∞atio 48
111099 R15337 Hs 21958 Homo sapiens mRNA, cDNA DKFZp547D086 (fr 48
126142 H86261 Hs 40568 ESTs 48
126802 AW805510 Hs 97056 hypothetical protein FU21634 48
105848 AW954064 Hs 24951 ESTs 47
127987 AI022103 Hε 124511 ESTs 47
129706 AA443241 πbosomal protein L44 47
129598 N30436 Hε 11556 Homo sapienε cDNA FLJ12566 fis, clone NT 47
126629 AL096739 Hε 107260 hypothetical protein DKFZp586H0623 47
111348 AA034922 Hε 9585 ESTs 47
100448 AF234887 Hs 57652 cadhenn EGF LAG seven-paεs G-type rxe 47
127542 AA703684 Hs 179833 ESTs, Moderately similar to ALU5.HUMAN A 47
132452 AW973521 Hs 247324 mitxhondπal πbosomal protein S14 47
123778 AW352149 Hs 102314 ESTs 47
126521 AI475110 Hs 203933 ESTs 47
110343 AW136703 Hs 17268 ESTs 46
102963 X02404 Hs 274534 calcitonin related polypeptide, beta 46
127207 AA377165 Hs 44833 ESTs 46 113974 AW969756 Hs 34145 ESTε, Weakly similar to B49647 GTP bmdi 46
133098 AW629223 Hs 64794 zinc finger protein 183 (RING finger, C3 46
109920 H05840 Hε 111323 ESTs 46
103487 AA743603 Hs 172108 nucleopoπn 88kD 46
125353 AB033043 Hs 149377 hypothetical protein DKFZp761L0424 46
100893 BE245294 Hs 180789 S164 protein 46
135047 AL134197 Hs 93597 cyclm-dependent kinase 5 regulatory su 46
111148 AB020690 Hs 7782 paraneoplastic antigen MA2 46
107681 BE379594 Hs 49136 ESTs Moderately similar to ALU7.HUMAN A 46
108480 AL133092 Hs 68055 hypothetical protein DKFZp434l0428 45
132742 AA025480 Hs 292812 ESTs Weakly similar to T33468 hypotheti 45
104912 AA813192 Hs 200596 KIAA0547 gene product 45
110223 H19836 Hs 31697 ESTs 45
113047 AI571940 Hs7549 ESTs 45
101031 J05070 Hs 151738 matnx metalloprotemase 9 (gelatmase B 45
113002 BE243513 Hs 7212 hypothetical protein PP1044 45
105304 AW134924 Hs 190325 ESTs 45
112386 AA831785 Hs 171914 Homo sapienε cDNA FLJ14209 fiε clone NT 45
106489 AA452054 Hs 119338 ESTε 45
122792 AW188551 Hs 99519 hypothetical protein FU14007 45
112651 AA595802 Hs 33410 ESTs Weakly similar to T17279 hypotheti 45
111346 AW970976 Hs 293653 ESTs 45
123596 AA421130 Hs 112640 EST 45
125447 AI582222 Hs 128686 ESTs 45
106178 AL049935 Hs 301763 KIAA0554 protein 44
102250 AI249361 Hs 74122 caspase 4 apoptosis related cysteine pr 44
105868 AA378780 Hε 334842 tubulin alpha 1 44
127496 AI031650 ESTε 44
127315 AF116622 gb Homo εapiens clone FLB4217 mRNA seque 44
110193 AI004874 Hε 310764 Homo sapienε mRNA cDNA DKFZp434M082 (fr 44
105012 AF098158 Hs 9329 chromoεome 20 open reading frame 1 44
129445 W52452 Hs 29797 nboεomal protein L10 44
114721 D61939 Hε 103822 ESTε 44
120922 AA481003 Hs 97128 ESTε 43
115167 AA749209 Hs 43728 hypothetical protein 43
102407 AW602154 Hs 82143 E74-lιke fxtor 2 (ets domain transcπpt 43
106111 AW875398 Hs 6451 PRO0659 protein 43
123829 AF251237 Hs 112208 XAGE-1 protein 43
103616 NM.002647 Hs 32971 phosphoιnoειtιde-3-kιnaεe class 3 43
100269 NM 001949 Hε 1189 E2F transcnption fxtor 3 43
112728 R91913 Hε 272104 ESTs, Moderately similar to ALU1.HUMAN A 43
135098 AW274526 Hε 277721 membrane ∞mponenL chromoεome 17, surfa 43
106034 AW952005 Hε 14928 hypothetical protein FU 12903 43
133571 BE515037 Hε 177556 melanoma antigen family D, 1 43
106246 AL036917 Hε 288821 KIAA1638 protein 43
125724 AL360190 Hε 318501 Homo sapieπε mRNA full length insert cDN 43
132206 AA425204 Hε 334721 hypothetical protein FU13391 43
130227 BE397151 Hs 153003 εeπne/threonine kinase 16 43
129650 AF109298 Hs 118258 prostate cancer assxiated protein 1 43
130382 NM.003450 Hε 155204 zinc finger protein 174 43
106073 AL157441 Hs 17834 downstream neighbor of SON 42
105403 AI473827 Hs 31793 ESTs 42
118138 AA374756 Hs 93560 Homo sapiens mRNA for KIAA1771 protein, 42
134126 NM 003747 Hs 131814 tankyrase, TRF1 interxting ankyπn rela 42
115041 AA252457 Hs 86543 ESTs, Moderately similar to T00256 hypot 42
106012 AI240665 ESTs 42
116732 AW152225 Hs 165909 ESTs, Weakly similar to I38022 hypotheti 42
130832 AW838006 Hs 20082 zinc finger protein 3 (A8-51) 42
125960 AI754693 Hε 145968 ESTs 42
133916 AL039185 Hs 77558 thyroid hormone receptor mterxtor 7 42
106232 AB037828 Hs 15370 KIAA1407 protein 42
129228 U40714 Hs 239307 tyrosyl tRNAεynthetase 42
109929 AA773187 Hs 294027 ESTε 42
123729 AL039779 Hs 278672 membrane ∞mponent chromosome 11, surfa 42
101266 L36645 Hs 73964 EphA4 42
132389 AA310393 Hs 190044 ESTs 42
124320 H95749 Hs 102342 EST 42
103023 AW500470 Hs 117950 multifunctional polypeptide similar to S 41
116133 AW449597 Hs 313652 EST, Weakly similar to 138022 hypothetic 41
129001 AA443323 Hs 107812 BPOZ protein 41
119271 AI061118 Hs 65328 Fanconi anemia, complementation group F 41
114767 AI859865 Hs 154443 minichromosome maintenance deficient (S 41
126107 H75477 Hs 93361 ESTε 41
115333 BE241812 Hs 87860 protein tyroεine phoεphataεe non rxept 41
100571 L14561 Hs 78546 ATPase Ca++ transporting plasma membra 41
134104 L35253 Hs 79107 mitogen xtivated protein kmase 14 41
120150 BE005771 Hs 153746 hypothetical protein FU22490 41
134470 X54942 Hs 83758 CDC28 protein kmase 2 41
129948 AI537162 Hs 263988 ESTs 41
106882 AA149537 Hs 26994 hypothetical protein FU20477 41
126199 AW088276 Hs 125829 ESTs 41
112727 T91029 Hs 15069 ESTs 41
118872 AI039201 Hε 283316 ESTs 41 131263 AU077002 Hs 24950 regulator of G-protein signalling 5 40
134417 NM 06416 Hs 82921 solute camerfamily 35 (CMP sialic xi 40
113609 T93263 Hs 16875 ESTs, Weakly similar to S23650 retroviru 40
127153 AI732303 Hε 186518 hypothetical protein MGC2599 similar to 40
124105 H11484 Hs 79133 ESTs 40
100031 AFFX control - DapX 40
106897 AF039023 Hs 167496 RAN binding protein 6 40
128659 AW630087 Hs 103315 tπnucleotide repeat containing 1 40
133928 AW403084 Hs 7766 ubiquitin-conjugatmg enzyme E2E 1 (homo 40
126965 AI470523 Hs 139336 ATP binding cassette sub-family C (CFTR 40
103100 NM 005574 Hs 184585 LIM domain only 2 (rhombotm like 1) 40
119005 AL038511 Hs 125316 ESTs, Weakly similar to S33990 finger pr 40
118751 N74210 Hs 50454 ESTs 40
128797 NM 002975 Hs 105927 stem cell growth fxtor, lymphxyte sxr 40
111387 AI244489 Hs 285724 ESTs 40
118676 N45312 Hs 46506 ESTs 40
107348 AW973753 Hs 182426 πbosomal protein S2 40
120528 AI923511 Hs 104413 ESTs 40
115652 BE093589 Hs 38178 hypothetical protein FLJ23468 40
102935 BE561850 Hs 80506 small nuclear πbonucleoprotein polypept 40
115399 AF151534 Hs 92023 core histone macroH2A22 40
133615 M62843 Hs 75236 ELAV (embryonic lethal, abnormal vision 40
118129 N57493 gb yy54c08 s1 Soareε.multiple.εclerosis. 40
126522 W31912 Hs 21168 gb zc76d03 ε1 Pancreatic Islet Homo sapi 40
131965 W79283 Hs 35962 ESTs 39
102507 U52154 Hs 193044 potaεsium inwardly rectifying channel, s 39
126029 AA704253 Hs 169359 ESTε 39
107168 W57578 Hs 237955 RAB7, member RAS oncogene family 39
105808 AI133161 Hs 286131 CG1 101 protein 39
134087 U51166 Hs 173824 thymme-DNA glycosylase 39
133195 AI434760 Hs 279949 KIAA1007 protein 39
112996 BE276112 Hs 7165 zinc finger protein 259 39
129428 AA256906 Hs 111364 ESTs, Weakly similar to ubiquitous TPR m 39
118967 AI668670 Hs 216756 ESTs 39
127335 AA830210 Hs 214263 ESTs Moderately similarto ALULHUMAN A 39
106636 AW958037 Hs 286 πbosomal protein L4 39
133529 W45623 Hε 74571 ADP-πbosylation fxtor 1 39
102266 U29725 Hε 3080 mitogen activated protein kinaεe 7 39
125905 AI678638 Hε 6456 chaperonin containing TCP1 , subunit 2 (b 39
103080 AU077231 Hε 82932 cyclin D1 (PRAD1 parathyroid adenomatos 39
131971 BE567100 Hs 154938 hypothetical protein MDS025 39
129703 BE388665 Hs 179999 Homo sapiens, clone IMAGE 3457003, mRNA 39
128895 AW467000 Hs 106985 ESTs 39
110924 AW058463 Hs 12940 zinc-fingers and hom∞boxes 1 39
112921 R91095 Hs 4276 KIAA1701 protein 39
120820 AA347417 Hε 96869 EST 38
106459 AA789081 Hε 4029 glioma amplified sequence 41 38
114253 BE149866 Hs 14831 Homo sapiens, Similar to zinc finger pro 38
105476 AL117352 Hs 77196 Human DNA sequence from clone RP5-876B10 38
122682 AA984531 Hs 159293 ESTs 38
130580 N32388 Hs 334370 uncharxteπzed hypothalamus protein HBE 38
130174 M29551 Hs 151531 protein phosphataεe 3 (formerly 2B), cat 38
115577 AA393167 Hε 41294 ESTε 38
129785 H19006 Hs 184780 ESTε 38
126127 N95428 gb zb80d09 s1 Soareε.εeneεcenLfibroblaε 38
109793 F13088 Hs 8040 heparan sulfate (glucoεa iπe) 3-O-sulfot 38
103175 X69089 Hε 79227 myomesin (M-protem) 2 (165kD) 38
100154 H60720 Hs 81892 KIAA0101 gene product 38
106140 AB006624 Hs 14912 KIAA0286 protein 38
129052 BE275031 Hs 158210 hypothetical protein MGC2555 38
103319 X83492 Hs 82359 tumor nxrosis fxtor rxeptor superfami 38
106319 W22335 Hs 7392 hypothetical protein MGC3199 38
102391 AA296874 Hs 77494 deoxyguanoεine kinase 38
127262 AA828125 gb od71a09 s1 NCI CGAP Ov2 Homo sapiens 37
126872 AW450979 gb Ul-H BI3-a!a-a-12-0-UI s1 NCI_CGAP.Su 37
107315 AA316241 Hs 90691 nucleophosm /nucteoplasmin 3 37
113119 T47910 gb yb18b11 s1 Stratagene fetal spleen (9 37
126962 R12014 Hs 20976 ESTs 37
116203 AW137166 Hs 87306 ESTs 37
123377 AW969183 Hs 271297 ESTs 37
122798 AW366286 Hs 145696 splicing fxtor (CC1 3) 37
107780 AA018927 Hs 269213 ESTs 37
132733 AB020631 Hs 123654 PCF11p homolog 37
120649 AA687322 Hs 192843 leucine zipper protein FKSG14 37
131163 AA099524 Hε 23754 ESTs 37
126708 AW962593 Hε 135260 ESTs 37
117417 AI241733 Hε 43871 ESTs 37
106272 AW959731 Hε 323099 ESTs 37
110834 AW273860 Hε 5759 ESTs 37
123663 AL039482 Hε 142517 Homo εapiens mRNA, cDNA DKFZp434P0810 (f 37
124250 AA350256 EST, Weakly similar to 2109260A B cell g 37
127038 AA233014 Hε 105965 ESTε 37
107711 W96141 Hε 220687 ESTε 37 130850 AB040922 Hs 20237 DKFZP566C134 protein 37
119126 R45175 Hs 117183 ESTs 37
125466 R08234 Hs 180461 ESTs 36
105150 AA631977 Hs 155995 KIAA0643 protein 36
103163 AU077018 Hs 3235 keratin 4 36
104495 AW975687 Hs 292979 ESTs 36
107599 AW664072 Hs 60136 ESTs 36
113577 AI300699 Hε 111334 PRO0470 protein 36
102681 Y08890 Hε 113503 karyophenn (importin) beta 3 36
109411 R98881 Hε 109655 sex comb on idleg (Drosophila) like 1 36
127563 AB035898 Hε 150587 kinesm like protein 2 36
131112 H15302 Hs 168950 Homo sapiens mRNA, cDNA DKFZp566A1046 (f 36
114118 F01598 Hs 175930 ESTs 36
103937 AA934063 Hs 13836 ESTs, Weakly similar to 138022 hypotheti 36
125174 W51835 Hs 231082 EST 36
104799 AA029703 gb ze95h08 s1 Soares_fetal_heart_NbHH19W 36
128952 AL043463 Hs 6755 RaP2 interxting protein 8 36
135191 X16866 Hs 333407 cytxhrome P450, εubfamily IID (debπsoq 36
124367 AI683183 Hs 99348 distal-less homx box 5 36
113560 T91015 ESTs 36
119232 AI655226 Hs 117659 ESTs, Weakly similar to T46481 hypotheti 36
113988 W87536 Hs 36473 ESTs, Weakly similar to JC5238 galactoεy 36
115173 BE612940 Hs 88252 ESTε 36
126600 AA699949 Hs 191385 ESTε 36
127256 AI738610 Hs 267967 ESTε, Moderately similar to ALU8.HUMAN A 36
123419 T66087 Hs 112482 Homo sapienε unknown mRNAεequeπce 36
102025 U04045 Hs 78934 mutS (E coli) homolog 2 (colon cancer, 36
100661 BE623001 Hs 132748 Homo εapienε πboεomal protein L39 mRNA, 36
132339 D80030 Hs 45127 chondroitin εulfate proteoglycan 5 (neur 36
115691 AW190215 Hs 62348 hypothetical protein FU11753 36
134853 BE268326 Hs 90280 5-amιnoιmιdazole-4-carboxamιde πbonucle 36
134075 NM 012201 Hs 78979 Golgi apparatuε protein 1 36
128468 T23625 Hs 150580 putative translation initiation fxtor 36
127229 AA316181 Hs 61635 six transmembrane epithelial antigen of 36
108451 AA079195 gb zm92h12 ε1 Stratagene ovanan cancer 35
133421 AF134160 Hs 7327 claudin 1 35
135332 AW393883 Hs 98968 hypothetical protein FU23058 35
132520 AA257992 Hs 50651 Januε kinase 1 (a protein tyroεine kinas 35
125562 A1494372 Hs 98968 hypothetical protein FLJ23058 35
126996 BE161065 Hs 167531 methylcrotonoyl Coenzyme A carboxylase 2 35
125558 R59305 gb yh16c10 r1 Soareε infant brain 1NIB H 35
117265 AA451966 RAB9 like protein 35
130215 BE301883 Hs 152707 glioblaεtoma amplified sequence 35
109482 AI002238 Hs 11482 splicing fxtor, arginme/seπne πch 11 35
133726 AI803188 Hs 252716 oxyεterol binding protein related protei 35
132317 BE262438 Hs 44592 beta-1,4 anπoεyltranεferaεe 35
117613 AW029507 Hs 161102 ESTε 35
100944 L07518 mucin 6, gastπc 35
105226 R58958 Hε 26608 hypothetical protein MGC15880 35
125032 T74884 gb yc58d02 s1 Stratagene liver (937224) 35
123720 AA609734 Hε 112755 EST 35
128846 AA730767 Hs 285753 SCG10-lιke-proteιn 35
116443 AW962196 Hs 339808 LBP protein 32 35
128770 AB015982 Hs 143460 protein kinase C, nu 35
106918 AA076049 Hs 274415 Homo sapieπε cDNA FU10229 fis, clone HE 35
131244 AI638429 Hs 24763 RAN binding protein 1 35
128765 AF073310 Hs 143648 insulin rxeptor εubεtrate 2 35
111223 AA852773 Hs 334838 KIAA1866 protein 35
104857 AI920902 Hs 19058 ESTs, Moderately similar to S65657 alpha 35
105395 AI580880 Hs 268149 putative methyltransferase 35
133582 BE391579 Hs 75087 Fas-xfivated εenne/threonine kinaεe 35
128527 AA504583 Hs 101047 tranεcπption fxtor 3 (E2A immunoglobul 35
106367 AA504747 Hs 136102 KIAA0853 protein 35
103392 X94563 gb H sapiens dbi/xbp gene exon 1 & 2 35
101086 AA382524 Hs 250959 histatin 1 35
133423 T84084 Hs 196008 Homo εapiens cDNA FU11723 fis, clone HE 35
117714 N45226 Hs 46495 EST 35
110986 AL133117 Hs 81376 Homo sapiens mRNA, cDNA DKFZp586L1121 (f 35
114096 AF060219 Hs 27007 chromosome condensation 1-lιke 34
117147 AW901347 Hs 38592 hypothetical protein FU23342 34
133347 BE257758 Hs 71475 xid cluster protein 33 34
132456 AB011084 Hs 48924 KIAA0512 gene product, ALEX2 34
133765 M62194 Hs 75929 cadhenn 11, type 2, OB-cadheπn (oεtxb 34
109734 AI927212 Hs 3734 ESTε 34
132786 BE083422 Hε 56851 hypothetical protein MGC2668 34
106685 AU076617 Hε 16251 cleavage and polyadenylation εpxificfa 34
105593 AA279341 Hε 174151 aldehyde oxidase 1 34
131381 M92642 Hε 26208 collagen, type XVI, alpha 1 34
108687 BE544475 Hε 54347 ESTs 34
113115 AI141426 Hs 8705 ESTs 34
107234 AA972447 Hs 288833 Homo sapiens mRNA, cDNA DKFZp434K087 (fr 34
123110 AA486256 Hs 193510 EST 34
131019 W28614 choπonic somatomammotropin hormone 1 (p 34 129079 AK000157 Hs 108502 hypothetical protein FLJ20150 34
111122 N63753 Hs 16492 DKFZP564G2022 protein 34
103934 BE278111 Hs 134200 DKFZP564C186 protein 34
128671 AI885045 Hs 211586 phoεphoinosifide 3-kιnase, regulatory εu 34
123258 AA490929 Hs 105274 ESTs, Weakly similar to RMS1.HUMAN REGUL 34
128826 Z40313 Hs 106330 Homo sapienε clone IMAGE 23371 , mRNA εeq 34
120149 AA227609 Hs 94834 ESTε 34
128817 BE395776 Hs 168640 ankyloεiε, progreεεive (mouεe) homolog 34
110679 AA004798 Hs 108311 ESTs, Weakly similar to T00351 hypotheti 34
122365 AA813546 Hs 99034 GTP-bmding protein Rho7 34
134455 BE378152 Hs 83530 hypothetical protein 34
115506 AB037756 Hs 45207 hypothetical protein KIAA1335 34
134267 AH 74596 Hs 196209 RAE1 (RNA export 1, S pombe) homolog 34
106691 AA443164 Hs 23259 hypothetical protein FU 13433 34
105169 BE245294 Hs 180789 S164 protein 34
120120 BE547267 Hs 59791 hypothetical protein MGC13183 34
126638 AA649257 Hs 86998 ESTs 34
128531 H03721 Hs 63236 πbosomal protein S15a 33
106650 AL049951 Hs 22370 Homo sapiens mRNA, cDNA DKFZp564O0122 (f 33
108859 AL121500 ESTs 33
112276 R53442 Hs 26038 ESTs, Weakly similar to I38022 hypotheti 33
125693 H23989 Hs 169743 Homo sapiens clone 25121 neuronal olfact 33
113474 R50752 Hs 23856 hypothetical protein MGC5297 33
132994 AA112748 Hs 279905 clone HQ0310 PRO0310p1 33
124691 R05835 Hs 110153 ESTs 33
112511 AW970420 dynxtin 2 (p50) 33
132985 AL045579 Hs 62113 KIAA0717 protein 33
125743 H17151 Hs 7416 gb ym37a05 r1 Soares infant brain 1 NIB H 33
133363 AI866286 Hs 71962 ESTs, Weakly similarto B36298 proline-r 33
107908 AF087999 ESTε 33
105312 BE613348 Hs 211579 melanoma cell adheεion molxule 33
110256 H63947 Hs 237955 RAB7, member RAS oncogene family 33
132073 AA295052 Hs 38516 Homo εapiens, clone MGC 15887, mRNA, com 33
107090 AW809208 Hs 183297 DKFZP566F2124 protein 33
105463 AA825974 Hs 32646 hypothetical protein FU21901 33
109592 AI198059 Hs 26370 ESTs 33
113649 N94768 Hs 16400 ESTs, Weakly similarto KIAA1435 protein 33
103898 AA248884 gb k3517 seq F Human fetal heart, Lambda 33
116439 AA251594 Hs 43913 PIBF1 gene product 33
129535 AA397972 Hs 112603 chimeπn (chimaenn) 1 33
113283 T66813 Hs 12947 EST 33
128992 H04150 Hs 107708 ESTε 33
133160 N54968 Hs 66309 hypothetical protein MGC11061 33
134076 AF086215 Hs 78980 gb Homo εapienε full length insert cDNA 33
128301 U90552 Hs 284283 butyrophilm, subfamily 3, member A1 33
127728 AW404061 protein kinase C, beta 1 33
126516 R95872 Hs 117572 chemokine binding protein 2 33
127506 T61039 Hs 76067 nbosomal protein L10a 33
104769 AA025887 Hs 293943 hypothetical protein MGC11266 33
126666 AA648886 Hs 151999 ESTs 33
130453 U80735 Hs 173854 PAXtranεcπpfion xfivation domain inte 33
107131 AW961605 Hs 21145 hypothetical protein RG083M052 33
130422 AW160614 Hs 180034 cleavage εtimulafion fxtor, 3' pre-RNA, 33
121292 AA401807 gb zv65f11 ε1 Soareε total fetus Nb2HF8 33
123284 AA488988 Hs 293796 ESTs 33
130734 AW137091 Hε 18624 KIAA1052 protein 33
105400 AF198620 Hs 10283 RNA binding motif protein 8A 33
105014 AA121123 Hs 269267 ESTε, Weakly similar to AF161361 1 HSPCO 33
114988 AA251089 gb zs04f05 s1 NCLCGAP.GCB1 Homo sapiens 33
132867 AF226667 Hs 58553 CTP synthase II 33
124169 BE079334 Hs 271630 ESTs 33
114652 AI521936 Hs 107149 novel protein similar to archaeal, yeast 33
113876 AI799751 Hs 5635 ESTs 33
111520 AI985369 Hε 301134 ESTs 33
121748 BE536911 Hε 234545 hypothetical protein NUF2R 33
106834 AL044182 Hε 28070 KIAA0753 gene product 33
128869 AA768242 Hε 80618 hypothetical protein 33
129619 AA209534 Hε 284243 tefraεpan NET-6 protein 33
126770 AI292320 Hε 81361 heterogeneouε nuclear πbonucteoprotem 33
116734 AW900992 Hε 93796 DKFZP586D2223 protein 33
100253 D38024 Hs 157425 double homxbox, 2 33
130999 AA326683 Hs 21992 likely ortholog of mouεe vaπant polyade 33
114092 H81213 Hε 14825 ESTε, Weakly similar to KIAA1503 protein 33
129284 AA318224 Hs 296141 ESTs 33
119127 AA708035 Hs 12248 ESTs 33
123910 AA621262 Hs 179923 ESTs, Weakly similar to S65657 alpha-1 C- 33
132664 AI740461 Hs 54542 ESTε 33
118397 BE139479 Hε 161492 ESTs 33
107003 AW138437 Hε 24790 KIAA1573 protein 33
126735 M69113 Hε 226795 glutathione S transferase pi 32
130847 AI672483 Hε 20220 lipase protein 32
101186 AA020956 Hε 179881 core-binding fxtor, beta subunit 32
113626 T94318 Hε 17359 ESTs, Moderately similar to RL44_HUMAN 6 32 121782 AW452957 Hs 63348 Homo sapiens, clone MGC 15203, mRNA com 32
119863 AA081218 Hs 58608 Homo sapiens CDNA FU14206 fis clone NT 32
106103 BE620779 Hs 12094 mitxhondnal nbosomal protein L30 32
123808 AA620552 gb ae58g11 s1 Stratagene lung carcinoma 32
133761 AF041430 Hs 75922 brain protein 13 32
110561 AA379597 Hs 5199 HSPC150 protein similarto ubiquitin-con 32
115239 BE251328 Hε 73291 hypothetical protein FU10881 32
117457 N29682 Hε 44071 ESTs, Weakly similar to ALU5.HUMAN ALU S 32
128862 BE250742 Hs 106673 eukaryotic translation initiation fxtor 32
129673 D38552 Hs 1191 KIAA0073 protein 32
105154 AA307279 Hs 35947 methyl CpG binding domain protein 4 32
126722 N66148 Hs 11125 HSPC033 protein 32
109966 H09103 Hs 30897 EST 32
129315 NM.014563 Hs 174038 spondyloepiphyεeal dysplasia late 32
109517 AI631874 Hs 155140 casein kmase 2, alpha 1 polypeptide 32
105252 AB039670 Hs 9728 ALEX1 protein 32
101754 S70114 Hs 239489 TIA1 cytotoxic granule assxiated RNA-bi 32
110384 H45282 Hs 268798 ESTs 32
134118 BE336680 Hs 182877 KIAA0116 protein 32
134869 AL157518 Hs 90421 PR02463 protein 32
100780 BE561958 Hs 293441 immunoglobulin heavy constant mu 32
125728 AW954565 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger pro 32
129794 AF161399 hypothetical protein FU13433 32
129056 AI769958 Hs 108336 ESTs, Weakly similar to ALUE.HUMAN mi 32
107129 AC004770 Hs 4756 flap structure spxific endonuclease 1 32
103038 AA926960 CDC28 protein kinase 1 32
130553 AF062649 Hε 252587 pituitary tumor-transforming 1 32
125394 BE178502 Hs 173772 ESTs, Weakly similar to 178885 seππe/th 32
132305 AI806090 Hs 44344 hypothetical protein FU20534 32
131136 AB033099 Hs 23413 KIAA1273 protein 32
102983 BE387202 Hs 118638 non metaεtatic cells 1, protein (NM23A) 32
117639 AA377165 Hs 44833 ESTs 32
127076 AI422951 Hs 146162 ESTs 32
126153 H85692 Hs 40730 ESTs 32
132676 N92589 Hs 261038 ESTs, Weakly similarto I38022 hypotheb 32
104946 AW242407 Hs 73848 carcmoembryonie antigen related cell ad 32
122110 AI123000 Hs 301240 melaπxortm 1 rxeptor (alpha melanxyt 32
127705 AJ003322 gb AJ003322 Selxted chromosome 21 cDNA 32
109442 AW296134 Hs 86999 ESTs, Weakly similar to S65657 alpha-1 C- 32
100474 NM.000699 Hε 300280 amylase, alpha 2A, pancreatic 32
115536 AK001468 Hs 62180 anillin (Drosophila Scraps homolog), xt 32
119651 AW663858 Hs 333513 small inducible cytokine subfamily E, me 32
127211 AA305520 Hs 108812 hypothetical protein FU22004 32
134964 AI803516 Hs 272891 hφpxalcin like protein 4 31
105551 AW005822 Hs 25292 πbonuclease HI, large subunit 31
119750 AI538880 Hs 94812 ESTs 31
125590 R23858 Hs 143375 Homo εapienε, clone IMAGE 3840937, mRNA, 31
104590 AW373062 nuclear rxeptor εubfa ily 1, group 1, m 31
110724 AW016783 Hs 30799 Homo sapiens cDNA FU13471 fis, clone PL 31
116429 AF191018 Hs 279923 putative nucleotide binding protein, est 31
133915 AA815092 Hs 77554 Homo sapiens cDNA FU14967 fis, clone TH 31
128721 AW403911 Hs 266175 phoεphoprotein assxiated with GEMs 31
128538 R44214 Hs 101189 ESTε 31
129179 AW969025 Hs 109154 ESTε 31
108793 AA129395 Hs 71139 ESTε 31
108807 AI652236 Hs 49376 hypothetical protein FU20644 31
133461 NM 000762 Hs 334345 cytxhrome P450, subfamily IIA (phenobar 31
132571 AW674699 Hs 5169 suppresεor of G2 allele of SKP1. S cere 31
134937 AI251449 Hs 171939 ESTs 31
125756 BE174587 Hs 289721 growth arrest spxific transcπpt 5 31
112369 AW966243 Hs 4243 hypothetical protein FU12650 31
127002 AL353940 Hs 24979 hypothetical protein DKFZp761P1010 31
128179 AW293689 Hs 127116 ESTs 31
117121 H95044 Hs 321386 EST 31
126556 AF255303 Hs 112227 membrane-assxiated nucleic xid binding 31
128403 AI908006 Hs 295362 Homo sapiens cDNA FU14459 fis, clone HE 31
127930 AA809672 Hs 123304 ESTs 31
114250 AI914699 Hs 13297 ESTs 31
108828 AK001693 Hs 273344 DKFZP564O0463 protein 31
105225 AA211777 gb zn57d02 s1 Stratagene muscle 937209 H 31
117997 N52090 Hs 47420 EST 31
104558 R56678 Hs 88959 hypothetical protein MGC4816 31
124777 R41933 Hs 140237 ESTs, Weakly similar to ALULHUMAN ALU S 31
106035 N35568 Hs 5245 hypothetical protein FU20643 31
127521 AW297206 Hs 164018 ESTs 31
120215 AF109219 Hs 108787 phosphafidylmoεitol glycan, claεε N 31
119403 AL117554 Hs 119908 nucleolar protein NOP5/NOP58 31
105024 AA126311 Hs 9879 ESTε 31
123485 AI308876 Hs 103849 hypothetical protein DKFZp761D112 31
109416 BE268388 Hs 86945 ESTs, Weakly similarto A46010 X-lιnked 31
132490 NM.001290 Hs 4980 LIM domain binding 2 31
115348 AA281562 Hs 766 ESTs 31
117297 AW779829 gb hn88a05 x1 NCI_CGAP_Kιd11 Homo εapieπ 31 112501 AA972447 Hε 288833 Homo sapienε mRNA, cDNA DKFZp434K087 (fr 31
107532 AA443473 Hε 173684 Homo sapiens mRNA cDNA DKFZp762G207 (fr 31
130753 AA205223 Hε 189 phosphodieεterase 4C, cAMP-spxific (dun 31
132425 N87549 Hε 125287 zinc finger protein ZNF140-lιke protein 31
115188 AK000219 Hs 88367 hypothetical protein FU20212 31
129707 AW572317 Hs 12082 Homo sapienε mRNA cDNA DKFZp566L203 (fr 3 1
106474 BE383668 Hs 42484 hypothetical protein FLJ 10618 31
106472 AI207162 Hs 3815 stathmin like protein RB3 30
102687 NM 007019 Hs 93002 ubiquitin earner protein E2-C 30
117602 N35020 Hs 44685 C3HC4-lιke zinc finger protein 30
105522 W19789 Hs 336635 Homo sapiens, clone IMAGE 4179482, mRNA 30
133650 D84294 Hs 118174 tetratπcopeptide repeat domain 3 30
134624 AF035119 Hs 8700 deleted in liver cancer 1 30
112435 NM 013255 Hs 288791 muskelm 1, intracellular mediator ∞nta 30
134654 AK001741 Hs 8739 hypothetical protein FU10879 30
106651 AA460421 Hs 30875 ESTε 30
109597 AA989362 Hs 293780 ESTε 30
132342 AW162758 Hs 341729 ESTε, Weakly similar to ALU5_HUMAN ALU S 30
106057 BE614474 Hs 289074 F-box only protein 22 30
106378 AA824298 Hs 21331 hypothetical protein FU 10036 30
128660 AA011597 Hs 177398 ESTs 30
115467 AI366784 Hs 48820 TATA box binding protein (TBP) assxiate 30
128604 AI879099 Hs 102397 GIOT-3 for gonadotropin inducible traπsc 30
125219 AI804331 Hε 99423 ATP-dependent RNA helicase 30
126698 AI221147 Hε 145088 ESTs, Weakly similar to T15936 hypotheti 30
133966 BE280478 Hs 182695 hypothetical protein MGC3243 30
119155 R61715 Hs 310598 ESTs, Moderately similar to ALULHUMAN A 30
131586 AA460352 Hε 26966 KIAA1171 protein 30
100237 D30715 Human PAP (pancreatitis asεxiated prote 30
105515 T24968 Hε 23038 HSPC071 protein 30
123073 AA485061 Hε 105652 ESTε 30
111375 H56499 Hs 252692 ESTε, Weakly similarto I38022 hypotheb 30
130724 AK001507 Hs 44143 Homo sapienε clone FLB6914 PR01821 mRNA, 30
129928 AI338993 Hs 134535 ESTε 30
118922 AW206193 hypothetical protein DKFZp761B2423 30
131902 AA180145 Hs 34348 Homo sapiens mRNA, cDNA DKFZp434P0235 (f 30
125165 W45350 gb zc81h08 s1 Pancreatic Islet Homo sapi 30
122219 AA436002 Hs 183161 ESTs 30
132195 BE018717 Hs 42124 ESTε 30
102298 AA382169 Hs 54483 N myc (and STAT) mterxtor 30
103286 D38616 Hs 54941 phoεphorylaεe k ase, alpha 2 (liver) 30
130168 AK001389 Hs 15144 hypothetical protein DKFZp564O043 30
126997 AI377150 Hs 150914 ESTs 30
128902 AA036637 Hs 107052 ESTs 30
117186 H98988 Hs 42612 ESTs, Weakly similar to ALU1.HUMAN ALU S 30
126096 F08208 Hs 283844 similar to rat tπcarboxylate earner Ii 30
106711 BE390125 Hs 143187 hypothetical protein 30
114046 BE018658 Hs 141003 Homo sapienε cDNA FU21691 fiε, clone C 30
135029 H58818 hydroxyεteroid (17-beta) dehydrogenaεe 7 30
112003 AW978731 Hs 301824 hypothetical protein PR01331 30
106735 R77698 Hs 337778 ESTs 30
126628 N49776 Hs 170994 hypothetical protein MGC10946 30
133350 AI499220 Hs 71573 hypothetical protein FU10074 30
110312 BE256986 Hs 11896 hypothetical protein FU 12089 30
125659 T57693 Hs 87929 Homo sapiens cDNA FU 13707 fis, clone PL 30
129601 AB032964 Hs 115726 KIAA1138 protein 30
123423 AA598484 gb ae38f04 s1 Gessler Wilms tumor Homo ε 30
128695 NM.003478 Hs 101299 cullin 5 30
123470 AW303285 Human DNA sequence from clone RP11-110H4 30
109252 BE440157 Hs 85944 ESTs 30
101445 M21259 gb Human Alu repeats in the region 5' to 30
102126 AW950870 Hs 78961 protein phosphatase 1, regulatory (mhib 30
116475 AA733050 Hs 334612 small nuclear πbonucleoprotein polypept 30
106573 AA223447 Hs 12835 A kinase (PRKA) anchor protein 7 30
103106 W27172 Hε 1857 phosphodieεterase 6G, cGMP-spxrfic, rod 30
130755 BE293520 Hs 18910 prostate cancer overexpreεsed gene 1 30
112246 R51321 Hs 25780 Homo sapiens cDNA FU12252 fis, clone MA 30
126887 H20832 gb ym48d03 ε1 Soares infant brain 1 NIB H 30
117960 AA310417 Hs 47044 ESTs 30
133626 AW836130 Hs 75277 hypothetical protein FU 13910 30
113179 BE622021 Hs 152571 ESTs, Highly similar to IGF-II mRNA bind 30
109968 H09232 Hs 26484 HIRA-interxfing protein 3 30
125770 AA143045 Hs 81665 v kit Hardy-Zuckerman 4 feline εarcoma v 2 1
TABLE 71 B
Pkey Unique Eos probeset identifier number CAT number Gene cluster number
Acceεεion Genbank xceεεion numbers
Pkey CAT Number Accesεion 108451 13766_27 AA079195 AA084955 AA126308 AA084956 107908 46987.1 AF087999 N29296 AI928858 AA846757 N20229 AA026894 D80634 AW388923 AW388802 AW388957 AW571771 AW388839
AI686662 AW389079 AA602099 AW134567 AW517843 AI682674 AI474874 AA374167
123619 371681.1 AA602964AA609200 131495 142008.1 AA812434 AI831542 AA766261 AI769894 N63376 AA214392 AA135833 AW605017 AA135965 AW450072 H04812 AA446459
AW439151 AA426273 AI061423 AA598549 Z40087 AI753216 AA743075 AA854268 AA458920 AA843893 AI566516 AI864957
AI566634 AW971760 AA211796 AA430089
101445 1650 -5 M21259 100944 25682.2 L07518AW815215 117265 10421.1 AA451966 NM.016370 AB036693 AL139228 R58124 A1634847 AL119333 07356 AI334284 H29050 AI192685 AA652438
AW172843 W19794 N21460 AI743862 AW130622 AA991348 AI204553 AA992664 N80848 AA699329 AI824676 R26624 R49653
117297 647718.1 A 779829 N22494 A1248120 108859 137143 1 AL121500 AW291763 AI732432 AA129708 AA133309 AI733750 AI225224 125165 1852047 1 W45350 W45406 116790 19864 1 AW161357AI879062AI928938AW161097AW161167 BE314465 AA351715 F07096AA179034F08510 F00653AI936671
AA476718 AW772454 AI807703 R44253 AA976667 AI985186 AI650254 H38942 R84829 AA018724 AA001000 H85934 AA019126
H85609 AA017000 AA339355 AW950556 D51397 AA213981 BE548002 AI056359 AA001560 AW952113 AA317769 A1857477
AI857475AW249771 AW162661 H38943AA018628 R85885 AI984613 A1934765 A1796172 A 157488 AI929191 R85523 D51221
D53851 H85610 AI749674 F21582 AA323145 AA019127 AA687444 T06745 AI699293 H29532 AA214029 AA223656 NM_016834
X14474 R19697 H09695 R17455 R13812 R19056 AI681231 AI590200 R37671 AA861828 AI990023 AI935669 AW005821 AA324581
H17335 R37659 R42802 R46242 R60936 R59731 H28993 AA479907 R44570 AI890696 AA308884 AA507078 R41274 AI365507
T16348 AI560453 F03259 F04722T16312 AA016081 AW073061 BE314824 W28930 R44098 R51045
103038 15024.1 AA926960 AA926959 W76521 W24270 W21526 AA037172 BE267636 H83186 AA469909 N86396 AA001348 BE535736 AA081745
BE566245 AA082436 H72525 H77575 N49786 W80565 H78746 BE569085 W04339 R98127 T55938 BE279271 AW960304T29812
AA476873 BE297387 AA292753 AA177048 NM 001826 X54941 BE314366 AA908783 AI719075 BE270172 BE269819 AA889955
AI204630 W25243 AI935150 AA872039 W72395 T99630 AI422691 H98460 N31428 BE255916 H03265 AI857576 AA776920
AA910644 AA459522 AA293140 AW514667 R75953 AW662396 AA662522 AI865147 AI423153 AW262230 AA584410 AA583187
AW024595 AW069734 AI828996 AA282997 AA876046 AW613002 AA527373 AW972459 AI831360 AA621337 AA100926 AA772418
AA594628 AI033892 W95096 AI034317 AA398727 AI085031 N95210 AI459432 AI041437 AA932124 AA627684 AA935829
AI004827 AI423513 AI094597 H42079 R54703 AI630359 AA617681 AA978045 AA643280 W44561 AI991988 A1537692 AI090262
AA740817 AI312104 AI911822 AA416871 AI185409 AA129784 AA701623 AI075239 AI139549 AA633648 AI339996 AI336880
AA399239 AI078708 AI085351 AI362835 AI346618 AI146955 AI989380 AI348243 N92892 AA765850 AI494230 AI278887 AA962596
AI492600 W80435 AA001979 R97424 AI129015 N24127 AA157451 AA235549 AA459292 AA037114 AA129785 AI494211
AW059601 AW886710 R92790 N59755 AI361128 AW589407 H47725 H97534 H48076 H48450 T99631 AW300758 H03431 R76789
AA954344 H77576 R96823 AI457100 N92845 N49682 H42038 BE220698 BE220715 H99552 AA701624 N74173 R54704 H79520
H72923 H03266 BE261919 AA769633 AA480310 AA507454 AA910586 AI203723 AW104725 W25611 W25071 T88980 H03513
T77589 R99156 W95095 R97470 AA702275 T77551 AA911952 H82956 N83673 AA283672
126086 1606216.1 H75681 H70975
126098 1629789 1 M79088 N88221
125464 168460 1 N71807AA203399
126127 1205826.1 N95428 W24040 AW751366 H81987
125558 1703083 1 R59305 R19748
126426 110687.1 AA125984 AA127189 AA065075 AA070377 AA100017 AA079891 AA113255 AA075168 AA082764 AA083380 N84829 AA084752
AA076512 AA085119 AA085208 AA085045
118644 81501.1 AA443241 R23784 R67255 R00047 AI457612 R63254 R28645 R27616 H01310 R78329 R76046 R76055 AA369734 N57914 H94864
AI953638 R31669 AW769278 R82398 AA131925 R21776 R79031 AI129553 N70340 AI276116 AA709381 N63734 AI342605
AA327133 AI805980 AA005377 AW611716 T86946 AA369083 R67250 H00240 R32578 W86279 R80248 R23734 H00977 R21732
R78932 AA368675 R16780 R26523 H40161 W93671 R99823 R77956 H61601 R98785 R09738 H78317 H53537 H81056 T53780
H12600 R82345 AA653499 AW953717 R63207 R33888 H54071 H66993 T48748 AI702300 R30775 H68996 AI014957 AA369082
AF075351 AH 10886 AI742050 AW954245 AI768458 C19062 AI393674 C18911 C18029 AA708613 AI168432 R67389 AI168453
H00188 R21233 H03055 R53822 AA367558 R75872 W04151 AI220869 A1090290 AA368730 R94434 H81153 H70950 AA367783
H81514 H53536 C16968 C17797 C17677 C17064 AA082581 C17044 D63217 C18791 D78839 D63290 D78838 N91085 H54070
R80360 H78318 H40199 R33887 R02529 H94918 R00900 T87029 AA131924 R99891 AA004267 D78764 D78757 H61600 C18615
H60972 R98784 W86323 R09737 C17492 D78811 R67494 D78775 AA368244 H12650 D79043 AW957062 R82759 C19002 H01715
127262 231725 1 AA828125 AA834883 AA330555
127315 37938 1 AF116622 A1114507 AA640834 AA377999
103898 187213.-3 AA248884
126769 119008 1 AA083456AA127026AA084934AA120972AA085317
120147 386607 2 AI917116 AA633698 AI580389 Z39483
128080 1540039 1 F12310T66402 H07020
104590 44964.1 AW373062 T55662 AI299190 BE174210 AW579001 H01811 W40186 R67100 AI923886 AW952164 AA628440 AW898607
AW898616 AA709126 AW898628 AW898544 AA947932 AW898625 AW898622 AI276125 AI185720 AW510698 AA987230 T52522
BE467708 AW243400 AW043642 AI288245 AI186932 D52654 D55017 D52715 D52477 D53933 D54679 AI298739 AI146984
AI922204 N98343 BE174213 AA845571 AI813854 AI214518 AI635262 AI139455 AI707807 AI698085 AW884528 AI024768
AI004723 AW087420 AI565133 N94964 AI268939 AW513280 AI061126 AI435818 AI859106 AI360506 AI024767 AA513019
AA757598 X56196 AA902959 AI334784 AI860794 AA010207 AW890091 AW513771 AI951391 AI337671 T52499 AA890205
A1640908 H75966 AA463487 AA358688 AI961767 AI866295 AA780994 AI985913 BE174196 AA029094 AW592159 T55581 N79072
AI611201 AA910812 AI220713 AW149306 AI758412 AA045713 R79750 N76096
127496 340470 1 AI031650 AA860882 AI458212 AA524453
126872 142696.1 AW450979 AA136653 AA136656AW419381 AA984358AA492073 BE168945 AA809054AW238038 BE011212 BE011359
BE011367 BE011368 BE011362 BE011215 BE011365 BE011363
126887 1572189 1 H20832Z40184
128132 177108 ϊ AA225632 AI820970 AI820952 AA226472 AI732140 AI732059 AA226307 AA225500
126967 169750 1 AA205976 AA205930
120325 166688 1 AA195651 AW235123
112511 17406 2 AW970420 AW973132 AA811736 AW301029 BE207945 AW449936 AI376801 AA039581 AI424444 AA810925 AA749267 BE205843
AI360184 BE205945 AI761796 AI185049 R94606 AI343947 AI565814 A1341735 AI749190 AW269588 AI393145 AI620080
AW003752 AI750035 AI624837 AI797658 AA679066 N87192 AI937537 AW003753 R72610 R72274 AA757401 AA553744 AA460166
AA535727 AW304422 R68273 AW027615 C01651 AI090327 AI538258 AW003744 AA938372 AW051486 AA505513 BE466452
AA931719 AI174548 AW182752 T84462 R11149 AI767627 BE218556 BE217986 BE222697 AI762382 BE299599 AA987212
AI767136 AI268928 AA090761 AA329290 AI700593 AA460766 BE222710 BE550651 R11148 AI979278 AW235819 AW874095
AW196492 106012 96214.1 AI240665T53681 N77468 H51833 AA147247 R75732 C18450 R73999 AI095755 T49904 H03868 AA411580 R33395 AA410586
T48869 D63292 R31981 H12498 H02668 AA035018 R75957 AI803329 R27528 R36203 AI809932 AI808765 R78948 AA411449
AA976929 A1378760 AI378620 T48870 R73906 R75632 H03612 AA909684 N50695 H02580 H12839 N58781 AA742532 AI360919
H03502 BE208298 R68588 AI350463 R31935 AW069127 AA411621 R25671 R36105 H12451 H03869 H51263 AA035486 R25109
R25110AA147933
127705 966283 2 AJ003322AJ003324
127728 3398 5 AW404061 R09654T67160 N50566 N53259
129012 22280 4 R81936 D78695 D78806 D78780 C17009 AA004406 AA122102 R70625 AA148932 H59583 H81146 H80378 H49863 H21182
H46534 H51478 H20702 H46515 H40200 H50046 H23647 H50439 H18383 H21846 H23849 H40182 R21924 H01290 H01283
H42464 W31947 W39660 AA046219 H03539 H01741 R22008 AA043911 AA156838 D78832 R36616 R66039 AI492481 AA088608
R69918 R36334 H80281 N58483 AI075154 A1086754 AA595787 H81051 H01187 AI057251 T96992 H59584 T47016 R31800
H13647 H01193 N74660 AA156601 H03455 R66040 R81937 R92416 H89486 R36617 R65795 AI088338 AI373324 H66992 R96235
AI494132 R16678 AA088178 AA705356 AA962143 AA148933 R09231 AI160937 R70525 T46980 AI200046 H02301 AA367587
R35968 T97106 D78703 N78072 D78668 D63268 R28197 AA085579 R63766 R92415 W00998 R80766 R67875 R27583 R09343
H13646 R27682T89007
106498 245223 AI221919 Z19967 AA348780 AW964077 AW166028 BE540193 N94800 AA452368 N99604 AI341345 AW298800 AA724961
AA931158 AI741227 AI806660 AI982626 D81263 D53937 D52496 AA974487 AW043854 N50483 Z39997 AI492961 AI361526
F04002 AA452141 T23551 AI472655 AI193667 A1341984 N92658 T32870 R52664 N50428 AW089291 AI934175 AI423737 D60665
120934 177521.1 AA226198 AA226513AA383773 115197 42406.1 R18656 AW968014 AA262288 AW968002 X93079 AJ002788 R51324 AI381600 D80031 AW500520 AW593740 F09382 AA810597
AA262174 AA810595 AA810596
129706 81501 1 AA443241 R23784 R67255 R00047 AI457612 R63254 R28645 R27616 H01310 R78329 R76046 R76055 AA369734 N57914 H94864
AI953638 R31669 AW769278 R82398 AA131925 R21776 R79031 AI129553 N70340 AI276116 AA709381 N63734 AI342605
AA327133 AI805980 AA005377 AW611716 T86946 AA369083 R67250 H00240 R32578 W86279 R80248 R23734 H00977 R21732
R78932 AA368675 R16780 R26523 H40161 W93671 R99823 R77956 H61601 R98785 R09738 H78317 H53537 H81056 T53780
H12600 R82345 AA653499 AW953717 R63207 R33888 H54071 H66993 T48748 AI702300 R30775 H68996 AI014957 AA369082
AF075351 AI110886 AI742050 AW954245 AI768458 C19062 AI393674 C18911 C18029 AA708613 AI168432 R67389 AI168453
H00188 R21233 H03055 R53822 AA367558 R75872 W04151 AI220869 AI090290 AA368730 R94434 H81153 H70950 AA367783
H81514 H53536 C16968 C17797 C17677 C17064 AA082581 C17044 D63217 C18791 D78839 D63290 D78838 N91085 H54070
R80360 H78318 H40199 R33887 R02529 H94918 R00900T87029 AA131924 R99891 AA004267 D78764 D78757 H61600 C18615
H60972 98784 W86323 R09737 C17492 D78811 R67494 D78775 AA368244 H12650 D79043 AW957062 R82759 C19002 H01715
131019 223488.3 W28614 W27435 AI983043 AA364395 AW572472 AW190386 AI129278 AI913081 AW473549 AA830713 AI982871 AI638647
AI828466 AW572486 N52583 N89687 AW075567 AI571047 AI887479 AI559469 AI685802 AA805256 AI458777 AA974369 AI866929
AI886032 A1823925 AI823566 AW198135 AI287510 AI565910 AA765775 AI866019 A1263697 AI355825 R42668 AA894603
AW105585 AI824555 AW339175 D20479
131170 8113.1 NM.014253 AF100772 BE088769 AL022718 BE161779 AW863569 BE161640 AL039060 BE168542 AW296554 AA323193
AA235370 AW779760 N48674 AI375997 R45432 D59344 AI203107 F07491 R35360 R25094 AI913631 AI498402 T61382 AI016320
N45526 T61415 AA331486 123470 8785.29 AW303285 AW117396 AA888929 BE174517 Z70704 AL042292 H54958 AA310063 AW499643 AW501380 AW501202 AW501293
AW501596 AW630166 AL041326 AA780690 L40517 U21556 AI093182 AW062487 AA883387 AA931302 BE252601 BE258381
AA827330 AL043930 AA356337 AW962830 AW393814 Z70703 AW389484 T62231 AW780049 AL043931 BE149744 AW963292
BE439669 BE091737 BE091657 AA484004 AI673095 AA599106 AW601545 AI538739 AI538730 AI521786 AW366369 AW021010
AA362576 AI289927 AA382592
123532 genbank_AA608733 AA608733
125032 genbank_T74884 174884
123808 genbank_AA620552 AA620552
102398 entrez_U42359 U42359
118129 genbaπk_N57493 N57493
109841 genbank_H01052 H01052
118922 220560J AW206193 AW137594 AI953685 AI919143 AI424371 AW007698 AW025681 AI954289 R40438 AW070364 A1679653 AI679081
AI623213 AI652310 AI631411 AI565384 A1566734 AA149597 AI538172 A1040831 AI770021 A1914287AA279311 W73001 AI493117
AI693374 AI802007 AI990645 N29752 R94559 AA806475 AA806828 R90998 R94558 AW300112 W24097 AW003016 N91920
113119 geπbank_T47910 T47910
104799 genbank_AA029703 AA029703
113560 genbaπk_T91015 T91015
129794 39565 1 AF093097 AI869509 T27070 AA326718 AA024743 W23922 AA479593 AI765668 W23908 U92986 AA081632 N50578 AA065245
AW365046 AW365014 AA961091 AA150231 H53426 AA234651 N50522 T79343 T87399 N91858 H41179 AW009453 AA024744
T27069AI346379 H88431 AA152289 R45373 AA477432 A1745607 AI807602 H41152AA065244 AI242569 AI091032AI251849
F03857 H88369 AI174488 A1002696 H53427 T87293 N91869 W35270 AA453723 AA453705 AW071829 AI393866 AW071807
W23592A1342074 D31158AA833756AI991896 AA447791 AI864125 AW377239AA295365 AI687970 R34076 F07607AA521310
AW499865 R94584 R21283
124250 314220.1 AA350256 H68126
101447 entrez_M21305 M21305
117357 genbank_N24829 N24829
103392 entrez X94563 X94563
135029 H58818 at H58818
105225 genbank_AA211777 AA211777
121292 genbank AA401807 AA401807
105909 82840.1 AA195191 AA190578 AI632307 AA195227 AA743633 AI823408 AI832203 AI653114 AA205307 AW021913 AI687980 AI674198
AI675563 AI417935 AA707350 AA135157 AI434721 AI151036 AIO38305 R52643 AA780141 AW207645 D19691 AI474370
AA401739 N22905 N70378
100237 entrez_D30715 D30715
114988 genbank_AA251089 AA251089
123423 genbank_AA598484 AA598484
Table 72A εhows the Seq ID No, Pkey, ExAccn, UnigenelD, and Unigene Title for all of the sequences in Table 73. Pkey: Unique Eos probeset identifier number '
ExAccn: Exemplar A∞esεion number, Genbank acceεεion number
UnigenelD: Unigene number
Unigene Title: Unigene gene title Seq ID No Seq ID number correlation for thoεe εequenceε in Table 73
Pkey ExAccn UnigenelD Unigene Title Seq ID No
103080 AU077231 Hs 82932 cyclin D1 (PRAD1 parathyroid adenomatos Seq lD No B B2
410102 AW248508 Hs 279727 ESTε, homologue of PEM-3 [Ciona εavignyi Seq lD No B3 & B4
101104 AW862258 Hs 169266 neuropeptide Y rxeptor Y1 Seq ID No B5 & B6
447761 AF061573 Hs 19492 protxadheπn 8 Seq ID No B7 & B8
428183 AW969726 Hε 98381 ESTε, Weakly similar to seπne protease Seq lD No B9 & B10
439221 AA737106 Hs 32250 ESTs, Moderately similar to 178885 seπn Seq lD o B11 & B12
121619 AA528339 Hs 178062 ESTs, Weakly similar to phosphatidylseπ Seq lD No B13, B14, & B15
104659 AW969769 Hs 105201 ESTs Seq ID No B16
105782 H09748 Hs 57987 B-cell CLL/lymphoma 11B (zinc finger pro Seq lD No B17 & B18
129977 NM 000399 Hs 1395 eariy growth response 2 (Krox-20 (Drosop Seq ID No B19 & B20
100299 D49493 Hs 2171 growth differentiation fxtor 10 Seq lD No B2 B22
116301 AW969706 Hs 293332 ESTε Seq lD o B23 & B24
106533 AL134708 Hs 145998 ESTs Seq ID No B25-B27
131313 R96290 Hs 75874 πbosomal protein L44 Seq ID No B28 & B29
105316 AI671245 Hs 24835 hypothetical protein FU 14594 Seq lD NoB30& B31
113003 AW292315 Hs 7215 ESTε Seq ID No B32
102836 U94320 Hε 158330 neuropeptide Y rxeptor Y5 Seq lD No B33 & B34
102745 AW753865 Hs 74376 olfxtomedin related ERI∞alized protei Seq ID No B35-B40
123308 C14187 Hs 157208 ESTε Seq lD No B4 B42
120147 AI917116 hemoglobin, beta Seq ID No B43
123049 BE047680 Hs 211869 diekkopf (Xenopuε laevis) homolog 2 Seq lD No B44 & B45
119082 AF252297 Hs 91546 cytxhrome P450 retinoid metabolizing pr Seq lD No B46 & B47
105301 AW352357 Hs7457 MAGE1 protein Seq lD No B48S B49
128478 AA708205 Hs 100343 ESTε Seq ID No B50-B53
106111 AW875398 Hs 6451 PRO0659 protein Seq ID No B54 & B55
131307 NM_000025 Hε 2549 adrenergic, beta-3-, rxeptor Seq lD No B56 & B57
120830 AI568170 Hε 96886 ESTa Seq ID No B58 & B59
127664 AA806164 Hs 116502 ESTε Seq ID No BΘO
102725 AB026187 Hs 159156 protxadheπn 11 Seq ID No B61 & B62
132520 AA257992 Hs 50651 Januε kinase 1 (a protein tyroεine kinaε \ Seq lD No B63 _ B64
130637 AA356764 Hs 17109 integral membrane protein 2A Seq lD No B65& B66
117602 N35020 Hs 44685 C3HC4-lιke zinc finger protein Seq lD No B67 & B68
128797 NM.002975 Hs 105927 εtem cell growth fxtor; lymphxyte sxr Seq lD No B69 & B70
129703 BE388665 Hs 179999 Homo sapiens, clone IMAGE 3457003, mRNA Seq ID No B71 & B72
125770 AA143045 Hs 81665 v-kit Hardy Zuckerman 4 feline sarcoma v Seq lD NoB73& B74
414761 AU077228 Hs 77256 enhancer of zeste (Drosophila) homolog 2 Seq ID No B75 & B76
420462 AF050147 Hs 97932 chondromodulin 1 prxursor Seq lD No B77 & B78
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of Seq lD No B79 & B80
104691 U29690 Hs 37744 Homo sapiens beta-1 adrenergic rxeptor Seq ID No B81 & B82
416836 D54745 Hs 80247 cholxystokinin Seq lD No B83 & B84
Table 72B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number
Acceεsion Genbank accession numbers
Pkey CAT Number Accession
131307 3138 1 NM 000025 X72861 X70811 M29932 X70812 S53291 AW015148 AW581776 AI276134 131313 93372.1 R96290 H02411 C18327 AA367588 AA367557 H89632 C17954 AA568860 AI752983 AA699451 H04260 AI128118 AW193364 N94503 AA029995 T40536 AA368746 AI189909 BE047384 AA747591 R22855 A1032539 AI151343 AA148534 H63941 T49595 AA694405 H74226 AI200363 R79731 AA702947 AI400076 AI088494 C17938 AA599478 H02962 R77665 C17370 R65618 H73711 R58545 D79189 AW265710 R77664 T52101 AW953745 AW953739 D79107 AA029105 AW953738 AA456487 R67000 AA156623 AA368336 H63662
116301 52669.2 AW969706 AA456258 AA491881 BE501639 D62113 AW969710 AI591236 AI379869 AW968997 AA040053 AI807206 AW663917 AA454645 AA489238 BE241958 AA743491 103080 17092.1 AU077231 AA852219 M74092 X59798 M64349 NM.001758 AA226806 M73554 BE409154 AA160096 BE384352 AA160820 BE382880 BE261734 AA113821 BE407745 AA156380 BE390287 BE390020 AA100854 AA127152 AW794066 AW367101 AW367093 U47703 AI347077 W05266 AI824103 AI499061 AA642944 AI042556 AA906539 W60380 AI571777 AL135581 AA112340 N75459 AA592929 AI085348 AI278890 AA126942AI023701 AI873252AA156319 AI190622 W60289 AI274886 R81309AA100801 AA227161 AI568929 AA160603 AI074344 AI344561 AI150778 AA852218 AA158286 N20142 AA622148 AA864225 AA576367 AW182124 T89175 AI758455 AA780573 N71757 R81200 AI659596 AI674613 AA642544 AW503909 AA128851 W39350 N40420 AA113072 BE168116 AI620604 AI298125 BE075272 N40078 BE075109 BE080779 AI918938 BE168117 BE087369 AW995539 BE080949 BE080727 BE075271 BE075108 BE080955 BE089655 BE081115 AW750304 H66084 AI146884 BE075154 AW992247 AI186525 AI752230 AW263140 W03329 N26056 AA948080 AA113073 H99284 AA227101 AA631077 AA148042 AI740837 BE082728 AA149570 W44495 BE089351 AA375044 N26775 H27771 AA064705 BE091204 R89337 N32676 N27141 BE164704 H98049 W67603 AA425549 W31090 AA807411 BE173280 BE000178 T09020 W23852 AA062709 BE167894 AA076515 R97329 BE541980 N42086 AA102307 AA113772 BE276181 H20622 W44436 W67604 W46412 AW771113 AI700678 AA502628 AA133137 BE274186 BE396090 BE613371 BE612645 W46650 W95203 W92651 AI087288 R76299 AW604781 N55320 AI912334 AA403248 AW169156 H24970 AW298822 AW080962 AI073747 W24123 AA577596 H21715 H27925 H26436 AI288304 AA148043 AA204678 BE047090 W48631 AA908347 AA599485 AI276505 AI953979 AA563710 H25674 H51747 AA425389 AA516104 AI095335 T77237 AA151696 T92084 AI689037 AI624162 W49709 AW514883 AA100676 AI366087 AA069474 AA525859 AW771076 AA029402 AA994114 AI351505 AW770816 AI333594 AI289794 AI346589 AA487700 AI081104 AA613344 AI377520 AI284911 AI311390 AA622062 AI055890 AI660881 AI366117 AA4O3090 AI272818 AI073353 W46300 AA062689 AI755078 AI753397 AI633564 AI273471 AI339890 AA699584 AA983722 AI079968 AI752231 AA076431 AA113245 AI168564 AA918965 AI066484 A1123599 AI921518 W94586 AA535600 AA064665 AA705388 AA064623 AA962503 AI924926 AW131206 AW275281 AI280632 T29597 W48728 AW954336 W38317 W94768 AI084717 W46567 AI245645 AW302501 N72201 AW510563 AW079132 AA207064 AI143740 AW440672 AA632154 AI290286 AI350704 AI271377 AA025369 AI864756 T77451 H97348 AA852165 AI932951 N98526 AA487486 R92970 AA934071 AI080448 AA063257 C05786 N99099 R42969 AA887065 AA662686 AA533833 AA662304 H51748 BE539444 AI382164 AI814595 BE537043 AI168307 BE408935 AA453606 R89428 AA936527 AA936890 AW369618 AW264602 R18074 AI474189 AW372354 AI094358 R37210 AA948510 AA226909 BE172527 AI086652 BE408324 AW292848 AI768962 BE540703 BE409478 AA931692 132520 45737.1 AA257992 AA317029 AA362097 D17042 H48100 AW838107 AW838106AW838110AW838231 AW610241 AW838442AA045061 AW384991
BE000988 M131806 BE180577AW838269AL039831 AI754380006051 AA131737 AW838239AI767465 AI480134AA610312AW838190
AA379252 AW838282 AA484027 AI423413 AI685064 BE328307 A1241857 AW838281 AW838284 AI671267 A1814928 AA828367 AI476306
AI270180 AA622362 AI076497 AI635919 AI444994 AI194028 AI669159 AI928131 AA448853 AI350143 AW079289 AW467807 AA480442
AA522935 BE180570 AW380087 AW380109 AI081015 AI690818 AI589485 AI698510 AA642019 AA714366 AI580430 AA985527 AI740475
C21398 AA257993 AI302393 AI689018 AW770194 AW753750 AI079164 BE550338 AA559851 T16108 AI864822 AI932827 AA045095
AA045062 AI954225 AA768569 AA709308 AW958363
117602 10565.-4 N35020 102725 115821 AB026187 NM 014522 U79247 F13304 AA224524 F10902 R39431 102745 131861 AW753865 F07644 F11280 F06355 F08136 U79299 F07459 F08750 F12419 F12842 F06488 F08585 F13403 F05921 F05512 F11683 F05416
F12841 F12810 F05418 F12850 R24551 F06276 H11803 H10237 H11542 H22894 R59563 H19351 H18722 F11237 F08507 H23123 R61595
F07796 F06201 F12289 F07107T78113 F08734 F13344 F05760 F11784 F08780 F05835 R20588 F07739 F11497 R17410 H17414 R20440
T66090 R25292 T66236T78766 T79908 R25286 R60071 C14761 AW905192 AA331914 AW965291 H09000 F05212 F08313 F05825 H06399
H15135 H11378 R66424 R61541 AA235405 AI205041 R59564 H23124 H18638 R37359 AI571275 R41780T66174T66159 R54102 W07657
H10794 R52337 R42890 H14354 R40952T17391 H12068 R56797 R51000 R60011 R37617 R39434 H29286T16403 H09129 R49114 H15161
H11729 R39160 H10468 H24454 H11432 R54433 H08768 H24042 H09511 H17281 H15292 R37849 AI991965 R52815 R42850 T17390T16438
T17388T16285 R48963 R50782 R44247 R46729 R59558 R40696 R43575 R44420 T17403 R37754 R46637 R51039 R40513T23785 F10433
T16350 H10191 R43688 T23543 H08591 R44351 R37575 R49508 F04379 F04056 F05067 F02010 F09158 F10036 F08900 F02559 F09914
F09434 F05034 H17415 F02644 H10650 F10451 H14589 F10444T16440 R44517 R46643 F03993 F10443 F02170 F09343 F10414 F04794
F11122 F04997 F03894 AW005932 F02767 F10941 F01777 R45260 F03386 R45261 T65009 F10990 F08942 F01673 H23253 F04533 F02082
F01669 F03689 H09568 R40763 H06400 R50958 N80570 AI082296 AI198226 T23763 AA814486 AW015823 AI886272 H06514 AA515969
F10049 AI984267 AI886279 AA558516 F02071 AI783843 AI804884 F01468 AA730438 AF035301 R38389 R41440 R59468 R14437 T89036
R43560 H10821 R52850 R56722 R14559 T09299 H10467 R25829 F13546 R56796 R51151 D82657 T32952 T66257 H06569 F12430 T74326
H08489 R34430 R13083 H23364 R21134T77098 AW957157 H24150 H11403 R52336 F12830 T77173 T74281 T77663 T74736 H10649 H12067
R20092T74735 R54530 R17552 R59557 R54529 H17280T75171 H14694T74975 H15291 R18574 R54157 R13446 H15221 R35120 R35031
R21277 R19632 R35820 R50899 R13923 R36771 R26485 R33061 R20100 H24426 H09184 H15958 R19253 H15196 H09510 R36032 R19691
H14402 H14885T17068
119082 34131.1 AF252297 N27888 F13415 R34552 R14377 AA323962 AW611514 AW614097 AW195487 AI026040 AI097663 AA012834 AW969885 AA988198
R49069 AW873673 R37774 F08840 AA484668 AW873664 AA170805 AA170825 AA585275 AA585280 AA012833
102836 253801 U94320 NM 006174 U66275 125770 16581.2 AA143045 AW271802 AI017093 AA450183 W93694 AI885044 AI890068 AW264522 AW073559 AI355325 AI051302 AI567686 AI143554
AI457891 AW468784 AI567693 AW884460 AI424892 AA401298 AW244098 AI122936 N24824 AA552932 AA873164 AI308810 N26098 H81852
N20798 AW263947 AI696267 AA449422 AW877967
120147 386607.2 AI917116 AA633698 AI580389 Z39483 113003 420161 1 AW292315 AI090408 AW517041 AI928695 AI092060 AA716741 N98235 T23629 104659 82594.1 AW969769 AA484137 AI291362 N64753 AL133784 AA007153 BE046923 D59990 C15166 D59991 D60194 AA648108 N76160 D61027 D60630 104691 41308.1 U29690 AF272890 AA708166 AA010748 R23839 H59572 R23383 AI625747 AA011176 AW665324 H02674 H59573 AA757931 H12502 R66851
AA702310 AA748431 AA749352 C01127 AI003679 T96352
105301 27795.5 AW352357 AA852419 T80568 AA332510 AW149659 AA341609 AA809550 AI183690 AA730875 T31719 AW965361 AA779709 T05461
AA564806 AI142536 AI553857 D53384 D53747 D54101 D55112 AW071935 AI082447 AI290911 AW168872 AA199743 AI091646 AI246702
AI271662 AW117296 AI032138 AI741489 AI538705 AA233541 AI682685 AW136268 AI689641 AA599916 AI174443 AI432175 AI131328
AW136277 AA852418 AA243035 T03902 C15651 D52660 H08108 AA844525 AI420648 AI282445 AW068986 AW497637 AA779042 AA298564
BE262936
105316 181763.1 AI671245 D81062 AI085879 AI193252 AI870535 N23132 H97661 H18098 AA552173 AA233924 AA503379 H19618 D60732 F04762 H11343
AW590283
127664 394361.1 AA806164 AA678564 AW978234 AW023951 AA651859 AI699785 AA913686 AW974569 AI681287 106111 4671.1 AW875398 A1064861 NM 014138 AF090943 BE071887 BE547232 BE622599 AI345700 AA284315 AA147700 AW376340 BE220170 BE348475
AA025037 AA057284 AA025038 T16193 AW130196 AW594516 AI989991 AI139091 AW675747 AA830435 AI924977 AI670778 AI051887
AA912574 AW130213 AI828335 AI570587 AI332760 AI313115 AA804653 AA477920 AA147645 AI916912 AW768839 AA715098 AA292723
AA732421 T33122 AI631560 AI698686 AI185386 R43829 AA421638 AA961400 C00503 AA604025 AA554026 AA553885 BE172244 R24040
128478 370722.2 AA708205 H15963 R20851 L13829 AI934608 AI950163 H92893 AI267243 N66614 H28983 R42031 H06198 AI468628 H92779 L13828 T34896
105782 246361 1 H09748 R61554 AA350215 R40551
120830 2444761 AI568170 AA731212 AW294848 AW466878 AA568908 AI281804 AI923633 AA347885 A1718854 AA714940
128797 20410.1 NM 002975 AF020044 AB009244 BE620464 AA541683 AW000991 AW089850 AW664612 AI636676 AI627854 AI885823 AI864548 AI554122
AI499682 AI570905 AI376008 AI871364 AI074230 AI383719 AA905016 AA977446 AA844732 T78922 AW244007 AI924747 AI968230 AI824575
AI699224 AI569490 AW379856 AW292314 AI016874 AW292037
106533 305354.1 AL134708 AW206610 AW665919 AW594227 AI917093 AI498361 AA635141 AA453786 D54178 D53224 AI804341 D53111 M78885 AL134707
AA453903 AI278054 AI334339 AI380496 AW235939 D60373 D60993 D81246
121619 284072J AA528339 AI017218 AA416911 123049 30801.1 BE047680 AF177395 NM.014421 AB033208 AB035181 W55979 AI093106 AI863392 AA715452 AA300480 AW022313 AA648103 AA720544
D61856 AA481794 AA737112 AW316551 AA714937 AW974378 AI370632 AI184289 A1333962 AA714945
129703 64196.1 BE388665 AA740614 AI394542 AA484451 AW070675 AA877654 AI360981 AI475799 BE349560 AL037351 N29437 AI246453 AW083444
AA844441 AI150871 AI440477 AI889061 AA682422 AA680053 AA740212AI858728AA490589AW243692AI249450AI304448AA534421
AI500317 AI273337 AW027729 AI979132 C06120 AI860916 AW591923 AI803174 AI559264 BE250500 AW675522 AA883284 T71033 AI346838
AI066754 AI197913 AA931979 AA427599 AI304730 AI285159 AI273325 AI038450 AI033760 N74972 AA136517 AI304446 AI262652 AA401348
AW514617AI361795 A 514389 N30307 N93439AA190775 BE349902 A1342114AI186831 AA039628 H74242 AI914825 AI955761 AI343851
AA693856 T71096 AI498539 AA778995 AA084278 AI274678 AI022673 AW339621 AA704929 AW089735 AA041252 AA161337 AI185333
AW189397 AI160990 AI082392 AI935848 AI144404 AI141633 AA447987 AA464241 AI342103 AW026118 AA834025 AW664459 AA603777
AA630752AA115450 N49944AW166071 AW769795AA991877AA873609AW083441 H99130AA910538AA486199AW083358 AA151767
AI161193 N54945 AA180193 AI423477AI188387 AI608747 N58900AI038449AA136852AA565913AA180502 H61741 AA701125 AI127678
AA278541 R76523 AA666187 H85083 F24755 R77729 AA135137 BE250395 R76239 AW794625 AW794404 H61957 AA308197 AW996031
AA345524 N52726 AA354360 AA179785 N57375 R16447 AA160645 W21481
100299 2801.1 D49493 NM.004962 D49492 AA948479 AA993843 AA017558 AA992567 AA912897 AI185363 AA018254 N93253 AA297544 T19187 R53287
AA069337 AA297489 N62906 AW023929 AA018253 AA017615 W25110 R52085 R52633 W16549 H88916 H89134 AA069338
129977 2039.1 NM 000399 AA018140 AF139463 J04076 AW390694 AW361756 AL079830 AI190587 AA731059 AA742743 AI635915 AA878209 AI262612
AI264201 AA446300 AA715016 AA446027 AI274101 AA593330 AA593338 AW015388 AI681724 AI347984 AL045275 AA970069 AA018188
AW014396 AW769445 AI588869 AW338296 AI801548 AI367702 AI888410
123308 3220091 C14187 AA496211 D80456 AA484051 D80455 AA528446 101104 264422 AW862258 L07615 130637 70401 AA356764 NMJ04867 AF038953 W16828 R50284 AI929589 R01594 AA010474 W37917 N64212 N78175 R57511 AA329322 W77834
AA169869 AA285240 AA356670 T93146 AA325779 AA357064 AA328151 AA306939 AA306801 N31260 AA306202 AA312530 BE242703
AA354371 N42259 AL021786 H50965 H38038 AI655965 AI566732 AI953952 AW972835 AI077300 AI948482 AI760966 AA648335 W72197
N32815 AA768073 AW338181 AW001742 AI819896 AI015666 N58011 AA677584 AH 83750 AW105514 W37875 AW301679 AA775257 AA730357 AI128690 AA630149 AW241515 AI147003 AI183499 N90923 AI968582 AA354145 AI147297 BE550502 AI085777 AI709087
AA773947 AA469192AI199289 AI127085 H89232 N30719AI028165AW029469AI709314AA780834 AA778057 H89125 AI654762T93061
N59622 AI360625 AA719982 AI248242 AA233925 AW262512 AW438666 AA010378 AA484010 AW438790 N22875 AA483718 AI185407
AA736720 AA664587 AA648672 AA503406 AA508123 AA503140 H46638 N75812 AA730938 D60546 AA483039 AA507705 AA480448
AI768654AA658955AA730803AA330312AW021127 BE172031 AW961052AA339070AA648172 BE172892AA174175AA492012AA491590
A 118733 AA484130 AA730783 AA730510 D62577 D62828 A1469294 AI801343 N53447 AA740226 AI831983 AA516146 D79799 AI758212
AA484040 H38039 AI038772 AI039410 AA52B387 AA730576 AA527231 AA748111 D62946 U38439 AA721708 H22130 AA559229 H51620
AA283355 AA730970 R01595 N72450 AA469123 AA579389 AA480477 AA283306 AA347822 AA328013
410102 117657 1 AW248508 AI278454 AI369343 AW291235 AI343946 AI347189 AA970152 AI279668 AI971894 AA664359 AI191039 AA084598 AA081641 410268 11897 1 AA316181 BE439545 AC005053 AF186249 AW386101 AC004969 AA730199 AA032221 AI686139 Al 167942 AA809228 AI184070 AI394674
AW969977 AA032279 AW079284 AA513174 AA888312 AI453179 AA483363 AA528432 AA579511
414761 14860.1 AU077228 U61145 AL044256 AA206185 AL044975 NM.004456 X95653 AW890905 AA332806 AW965453 BE299226 U52965 BE275009
AA428252 AA769212 AA312778 AA810901 AA461315 AI969286 AI953668 AW296248 AI291422 AA704747 Z44716 BE541235 AW608806
AA588583 AW403788 AW408386 AA053521 T87571 AA581163 BE183241 T97906 R89149 AI808196 BE618521 AI970278 AI652680 AW130143
AI970272 AW197254 BE550449 AI628403 AA010143 AW005107 AA251815 AA805836 N53459 AA055309 AA643678 AI345616 AI345618
AI635728 AI871286 AI018437 AI262514 H75287 AI033155 AI203388 AA205802 AI475265 AW594186 AI696059 AI333312 AW264710 AA876764
AA864892 AA173156 AI292066 T79837 W93995 AA506427 AA815135 AI376342 AA010144 AI310421 AI223350 AA970576 N33926 T89364
AI090913 N55098 AA101673 AA626665 AA251840 N68857 AI890053 H05930 AI474199 AI436166 AA628810 N64452 AI205538 AA055310
BE244495 AI365179 T99536 AI203088 Z40549 AW139858 AA599627 R91847 AA483681 AW068982 H51746 AA091201 H13030 AA459732
T99430 AI051764 R45991
416836 16233 1 D54745 AU077189 NM 000729 R71188 H87563 R80701 AW956319 AA376289 R82442 H46452 R22481 R64323 AW043690 L00354 AW005571
H19813 AI745597 AI769202 AI205982 AW205841 R64324 AI201975 H46993 Cl 8067 R71189 N29729 AI799838 AI091209 H87455 R82443
AW970995 AW072136 N40841 H13148 AI219052 N30191 T28007 AI817428 AA503602
420462 193791 AF050147 NM 007015 AB006000 AB005999 BE218114 AI703147 AI985891 BE222034 BE549774 BE327618 AI651459 BE549987 AI657194
BE222414 BE046984 AW470357 AW339338 C02526 AW590220 AI298082 AW296998 AI333135 AI867816 AA730514 BE348513 AA405500
AW136179 AA327834 BE327350 BE327366
428183 287965.1 AW969726 AA424028 AI266636 AI271571 AA423988 AI266634 AA702780 AA452037 AI424866 AA742931 AA483361 439221 46993.1 AA737106 N35765 N35779 AF086045 N30152 AW374028 AI478237 AA923562 AI382236 AA846668 AI627389 AI371709 H98083 H95983
H26576 H95984 AA745021 AA639180 H26575
447761 7355.1 AF061573 NM 002590 AA780138 AW135620 AI197884 AA483348 R05468 AW969724 H29216
Table 73 : Sequences
Seq ID NO: Bl DNA sequence
Nucleic Acid Accession #: NM_05305S.l
Coding sequence: 210..1097
1 11 21 31 41 51
I I I I I' I
CACACGGACT ACAGGGGAGT TTTGTTGAAG TTGCAAAGTC CTGGAGCCTC CAGAGGGCTG 60
TCGGCGCAGT AGCAGCGAGC AGCAGAGTCC GCACGCTCCG GCGAGGGGCA GAAGAGCGCG 120
AGGGAGCGCG GGGCAGCAGA AGCGAGAGCC GAGCGCGGAC CCAGCCAGGA CCCACAGCCC 180
TCCCCAGCTG CCCAGGAAGA GCCCCAGCCA TGGAACACCA GCTCCTGTGC TGCGAAGTGG 240
AAACCATCCG CCGCGCGTAC CCCGATGCCA ACCTCCTCAA CGACCGGGTG CTGCGGGCCA 300
TGCTGAAGGC GGAGGAGACC TGCGCGCCCT CGGTGTCCTA CTTCAAATGT GTGCAGAAGG 360
AGGTCCTGCC GTCCATGCGG AAGATCGTCG CCACCTGGAT GCTGGAGGTC TGCGAGGAAC 420
AGAAGTGCGA GGAGGAGGTC TTCCCGCTGG CCATGAACTA CCTGGACCGC TTCCTGTCGC 480
TGGAGCCCGT GAAAAAGAGC CGCCTGCAGC TGCTGGGGGC CACTTGCATG TTCGTGGCCT 540
CTAAGATGAA GGAGACCATC CCCCTGACGG CCGAGAAGCT GTGCATCTAC ACCGACAACT 600
CCATCCGGCC CGAGGAGCTG CTGCAAATGG AGCTGCTCCT GGTGAACAAG CTCAAGTGGA 660
ACCTGGCCGC AATGACCCCG CACGATTTCA TTGAACACTT CCTCTCCAAA ATGCCAGAGG 720
CGGAGGAGAA CAAACAGATC ATCCGCAAAC ACGCGCAGAC CTTCGTTGCC CTCTGTGCCA 780
CAGATGTGAA GTTCATTTCC AATCCGCCCT CCATGGTGGC AGCGGGGAGC GTGGTGGCCG 840
CAGTGCAAGG CCTGAACCTG AGGAGCCCCA ACAACTTCCT GTCCTACTAC CGCCTCACAC 900
GCTTCCTCTC CAGAGTGATC AAGTGTGACC CAGACTGCCT CCGGGCCTGC CAGGAGCAGA 960
TCGAAGCCCT GCTGGAGTCA AGCCTGCGCC AGGCCCAGCA GAACATGGAC CCCAAGGCCG 1020
CCGAGGAGGA GGAAGAGGAG GAGGAGGAGG TGGACCTGGC TTGCACACCC ACCGACGTGC 1080
GGGACGTGGA CATCTGAGGG CGCCAGGCAG GCGGGCGCCA CCGCCACCCG CAGCGAGGGC 1140
GGAGCCGGCC CCAGGTGCTC CCCTGACAGT CCCTCCTCTC CGGAGCATTT TGATACCAGA 1200
AGGGAAAGCT TCATTCTCCT TGTTGTTGGT TGTTTTTTCC TTTGCTCTTT CCCCCTTCCA 1260
TCTCTGACTT AAGCAAAAGA AAAAGATTAC CCAAAAACTG TCTTTAAAAG AGAGAGAGAG 1320
AAAAAAAAAA TAGTATTTGC ATAACCCTGA GCGGTGGGGG AGGAGGGTTG TGCTACAGAT 1380
GATAGAGGAT TTTATACCCC AATAATCAAC TCGTTTTTAT ATTAATGTAC TTGTTTCTCT 1440
GTTGTAAGAA TAGGCATTAA CACAAAGGAG GCGTCTCGGβ AGAGGATTAG GTTCCATCCT 1500
TTACGTGTTT AAAAAAAAGC ATAAAAACAT TTTAAAAACA TAGAAAAATT CAGCAAACCA 1560
TTTTTAAAGT AGAAGAGGGT TTTAGGTAGA AAAACATATT CTTGTGCTTT TCCTGATAAA 1620
GCACAGCTGT AGTGGGGTTC TAGGCATCTC TGTACTTTGC TTGCTCATAT GCATGTAGTC 1680
ACTTTATAAG TCATTGTATG TTATTATATT CCGTAGGTAβ ATGTGTAACC TCTTCACCTT 1740
ATTCATGGCT GAAGTCACCT CTTGGTTACA GTAGCGTAGC GTGGCCGTGT GCATGTCCTT 1800
TGCGCCTGTG ACCACCACCC CAACAAACCA TCCAGTGACA AACCATCCAG TGGAGGTTTG 1860
TCGGGCACCA GCCAGCGTAG CAGGGTCGGG AAAGGCCACC TGTCCCACTC CTACGATACG 1920
CTACTATAAA GAGAAGACGA AATAGTGACA TAATATATTC TATTTTTATA CTCTTCCTAT 1980
TTTTGTAGTG ACCTGTTTAT GAGATGCTGG TTTTCTACCC AACGGCCCTG CAGCCAGCTC 2040
ACGTCCAGGT TCAACCCACA GCTACTTGGT TTGTGTTCTT CTTCATATTC TAAAACCATT 2100
CCATTTCCAA GCACTTTCAG TCCAATAGGT GTAGGAAATA GCGCTGTTTT TGTTGTGTGT 2160
GCAGGGAGGG CAGTTTTCTA ATGGAATGGT TTGGGAATAT CCATGTACTT GTTTGCAAGC 2220
AGGACTTTGA GGCAAGTGTG GGCCACTGTG GTGGCAGTGG AGGTGGGGTG TTTGGGAGGC 2280
TGCGTGCCAG TCAAGAAGAA AAAGGTTTGC ATTCTCACAT TGCCAGGATG ATAAGTTCCT 2340
TTCCTTTTCT TTAAAGAAGT TGAAGTTTAG GAATCCTTTG GTGCCAACTG GTGTTTGAAA 2400
GTAGGGACCT CAGAGGTTTA CCTAGAGAAC AGGTGGTTTT TAAGGGTTAT CTTAGATGTT 2460
TCACACCGGA AGGTTTTTAA ACACTAAAAT ATATAATTTA TAGTTAAGGC TAAAAAGTAT 2520
ATTTATTGCA GAGGATGTTC ATAAGGCCAG TATGATTTAT AAATGCAATC TCCCCTTGAT 2580
TTAAACACAC AGATACACAC ACACACACAC ACACACACAC AAACCTTCTG CCTTTGATGT 2640
TACAGATTTA ATACAGTTTA TTTTTAAAGA TAGATCCTTT TATAGGTGAG AAAAftAACAA 2700
TCTGGAAGAA AAAAACCACA CAAAGACATT GATTCAGCCT GTTTGGCGTT TCCCAGAGTC 2760
ATCTGATTGG ACAGGCATGG GTGCAAGGAA AATTAGGGTA CTCAACCTAA GTTCGGTTCC 2820
GATGAATTCT TATCCCCTGC CCCTTCCTTT AAAAAACTTA GTGACAAAAT AGACAATTTG 2880
CACATCTTGG CTATGTAATT CTTGTAATTT TTATTTAGGA AGTGTTGAAG GGAGGTGGCA 2940
AGAGTGTGGA GGCTGACGTG TGAGGGAGGA CAGGCGGGAG GAGGTGTGAG GAGGAGGCTC 3000
CCGAGGGGAA GGGGCGGTGC CCACACCGGG GACAGGCCGC AGCTCCATTT TCTTATTGCG 3060
CTGCTACCGT TGACTTCCAG GCACGGTTTG GAAATATTCA CATCGCTTCT GTGTATCTCT 3120
TTCACATTGT TTGCTGCTAT TGGAGGATCA GTTTTTTGTT TTACAATGTC ATATACTGCC 3180
ATGTACTAGT TTTAGTTTTC TCTTAGAACA TTGTATTACA GATGCCTTTT TTGTAGTTTT 3240
TTTTTTTTTT ATGTGATCAA TTTTGACTTA ATGTGATTAC TGCTCTATTC CAAAAAGGTT 3300
GCTGTTTCAC AATACCTCAT GCTTCACTTA GCCATGGTGG ACCCAGCGGG CAGGTTCTGC 3360
CTGCTTTGGC GGGCAGACAC GCGGGCGCGA TCCCACACAG GCTGGCGGGG GCCGGCCCCG 3420
AGGCCGCGTG CGTGAGAACC GCGCCGGTGT CCCCAGAGAC CAGGCTGTGT CCCTCTTCTC 3480
TTCCCTGCGC CTGTGATGCT GGGCACTTCA TCTGATCGGG GGCGTAGCAT CATAGTAGTT 3540
TTTACAGCTG TGTTATTCTT TGCGTGTAGC TATGGAAGTT GCATAATTAT TATTATTATT 3600
ATTATAACAA GTGTGTCTTA CGTGCCACCA CGGCGTTGTA CCTGTAGGAC TCTCATTCGG 3660
GATGATTGGA ATAGCTTCTG GAATTTGTTC AAGTTTTGGG TATGTTTAAT CTGTTATGTA 3720
CTAGTGTTCT GTTTGTTATT GTTTTGTTAA TTACACCATA ATGCTAATTT AAAGAGACTC 3780
CAAATCTCAA TGAAGCCAGC TCACAGTGCT GTGTGCCCCG GTCACCTAGC AAGCTGCCGA 3840
ACCAAAAGAA TTTGCACCCC GCTGCGGGCC CACGTGGTTG GGGCCCTGCC CTGGCAGGGT 3900
CATCCTGTGC TCGGAGGCCA TCTCGGGCAC AGGCCCACCC CGCCCCACCC CTCCAGAACA 3960
CGGCTCACGC TTACCTCAAC CATCCTGGCT GCGGCGTCTG TCTGAACCAC GCGGGGGCCT 4020
TGAGGGACGC TTTGTCTGTC GTGATGGGGC AAGGGCACAA GTCCTGGATG TTGTGTGTAT 4080
CGAGAGGCCA AAGGCTGGTG GCAAGTGCAC GGGGCACAGC GGAGTCTGTC CTGTGACGCβ 4140
CAAGTCTGAG GGTCTGGGCG GCGGGCGGCT GGGTCTGTGC ATTTCTGGTT GCACCGCGGC 4200
GCTTCCCAGC ACCAACATGT AACCGGCATG TTTCCAGCAG AAGACAAAAA GACAAACATG 4260 AAAGTCTAGA AATAAAACTG GTAAAACCCC AAAAAAAAAA AAAAAA
Seq ID NO: B2 Protein sequence Protein Accession #: NP 444284.1
51 I I I I I I
MEHQ CCEV ETIRRAYPDA NLLNDRVLRA MLKAEETCAP ΞVSYFKCVQK EV PSMRKIV 60
ATWM EVCEE QKCEEEVFPL AMNYLDRFLS LEPVKKSR Q LGATCMFVA SKMKETIPLT 120
AEK CIYTDN SIRPEE Q ELLLVNKLKW NLAAMTPHDF lEHFLSKMPE AEENKQIIRK 180
HAQTFVALCA TDVKFISNPP SMVAAGSWA AVQG NLRSP NNF SYYR T RF SRVIKCD 240 PDC RACQEQ IEA ESSLR QAQQNMDPKA AEEEEEEEEE VDLACTPTDV RDVDI
Seq ID NO: B3 DNA sequence
Nucleic Acid Accession jf : XM_044166
Coding sequence: 1..1576
11 21 31 41 51
CTTTTGTTTC GCCATGCCTA GTCTAGTGGT ATCTGGAATA ATGGAAAGAA ATGGGGGCTT 60
TGGAGAACTA GGATGTTTCG GGGGAAGCGC TAAGGACCGA GGGCTGCTGG AAGACGAGCG 120
CGCCCTTCAG CTGGCTCTCG ATCAACTCTG CCTCCTGGGT TTGGGGGAGC CCCCCGCCCC 180
CAGGGCGGGC GAGGACGGGG GAGGTGGGGG GGGCGGCGCC CCCGCGCAGC CGACAGCCCC 240
CCCGCAGCCG GCGCCGCCGC CGCCGCCCGC GGCGCCCCCG GCCGCCCCGA CGACGGCCCC 300
CGCAGCGCAG ACGCCCCAGC CCCCCACCGC CCCCAAAGGG GCGAGCGACG CCAAGCTCTG 360
CGCTCTCTAC AAAGAGGCCG AGCTGCGCCT GAAGGGCAGC AGCAACACCA CGGAGTGTGT 420
TCCCGTGCCC ACCTCCGAGC ACGTGGCCGA GATCGTGGGC AGGCAAGGCT GCAAGATTAA 480
GGCCTTGAGG GCCAAGACCA ACACCTACAT CAAGACACCG GTGAGGGGCG AGGAACCAGT 540
GTTCATGGTG ACAGGGCGAC GGGAGGACGT GGCCACAGCC CGGCGGGAAA TCATCTCAGC 600
AGCGGAGCAC TTCTCCATGA TCCGTGCCTC CCGCAACAAG TCAGGCGCCG CCTTTGGTGT 660
GGCTCCTGCT CTGCCCGGCC AGGTGACCAT CCGTGTGCGG GTGCCCTACC GCGTGGTGGG 720
GCTGGTGGTG GGCCCCAAAG GGGCAACCAT CAAGCGCATC CAGCAGCAAA CCAACACATA 780
CATTATCACA CCAAGCCGTG ACCGCGACCC CGTGTTCGAG ATCACGGGTG CCCCAGGCAA 840
CGTGGAGCGT GCGCGCGAGG AGATCGAGAC GCACATCGCG GTGCGCACTG GCAAGATCCT 900
CGAGTACAAC AATGAAAACG ACTTCCTGGC GGGGAGCCCC GACGCAGCAA TCGATAGCCG 960
CTACTCCGAC GCCTGGCGGG TGCACCAGCC CGGCTGCAAG CCCCTCTCCA CCTTCCGGCA 1020
GAACAGCCTG GGCTGCATCG GCGAGTGCGG AGTGGACTCT GGCTTTGAGG CCCCACGCCT 1080
GGGTGAGCAG GGCGGGGACT TTGGCTACGG CGGGTACCTC TTTCCGGGCT ATGGCGTGGG 1140
CAAGCAGGAT GTGTACTACG GCGTGGCCGA GACTAGCCCC CCGCTGTGGG CGGGCCAGGA 1200
GAACGCCACG CCCACCTCCG TGCTCTTCTC CTCTGCCTCC TCCTCCTCCT CCTCTTCCGC 1260
CAAGGCCCGC GCTGGGCCCC CGGGCGCACA CCGCTCCCCT GCCACTTCCG CGGGACCCGA 1320
GCTGGCCGGA CTCCCGAGGC GCCCCCCGGG AGAGCCGCTC CAGGGCTTCT CTAAACTTGG 1380
TGGGGGCGGC CTGCGGAGCC CCGGCGGCGG GCGGGATTGC ATGGTCTGCT TTGAGAGCGA 1440
AGTGACTGCC GCCCTTGTGC CCTGCGGACA CAACCTGTTC TGCATGGAGT GTGCAGTACG 1500
CATCTGCGAG AGGACGGACC CAGAGTGTCC CGTCTGCCAC ATCACAGCCA CGCAAGCCAT 1560
CCGAATATTC TCCTAAGCCC CGTGCCCCAT GCCTCCGGGG CCCACTCCAC TGGGCCCACC 1620
CTGGACCTGT TTTCCACTAA AGCCTTTTGG AAAGCGGTGA TTTGAGGGGC AAGGTGCTTA 1680
GAGATACTCG CTCGCTGGGG AAGGGGGGAG GGAGGCAGTG GTGGCTGGAG GGTGCGCCAC 1740
TTTCAGAGCC TCTGGTCACC CTGTCCTGGA AAGATTGGGA GGGGGCCAGA CTGAAAATTT 1800
TACTAGAGTT ACAACTCTGA TACCTCAACA CACCCTTAAA TCTGGAAGCA GCTAAGAGAA 1860
ACTTTTGTTT TGCCAGAGGT GGCCACTAAG GCATTCTGAC GCCCTCTGCC CACCTCCCCC 1920
GCTGTGTGTC ACTCCACCCC TTCTTCCGAG GAGGGGGTGG GTAAAAGGGA GAGGGAGAAT 1980
TACCACCTGT ATCTAGAGGT GCTCTTTGCA ATCCCTAAGC CCTCTGGTCC TGACCTCCGA 2040
CCTCCCAGCT CTGTCTTGTT CCTTGTCTTT GTCTTTCTTC CCTTCCCCCT GCCCCTGCCC 2100
CTACCAGCCC AGCTTTGGGG ACACCATCCT TCTGGGGAGA AGTAGGGGGA GGAATATTTG 2160
GATGGTCCCT CCATTCCTCT TCAGGCATCT GGAGGCCCTC TCCCCCACTC CTCCAAAGAA 2220
ACATCTCAAA TTATTGATGG AATGTATCCC CATTCTCAGT GAAAATGTGA GGAGGGGACT 2280
AATACTGGGG TAAAGGGTCA AACCCCCACC TTCATCACTA TGGGCATTAT ATTTAGGGAG 2340
TAGTTCTTGG GCTGGATTTT CTGGTTGTGG AAGTGGGGGC GCCAGAGTAG TGTGTCTGCT 2400
ATTTAAAGGA GCAGGAAAGG GCGTGAGGCA GGAGGAGAGA CTGGTGGAGG GAAGAGCTGC 2460
TCCTCCCATG CAGTGCCCGA CTCCCTGCAC CCCTCTCAAC CTGACCTGAA CCTTTATTGA 2520
ATCCTTATTA GCTTGAATCC TTATTAGCTT GAATCCTCCA TGCAAATCAT GGAGTCTGTG 2580
TCCCACCTGA TGTGGTTGAG GAGAAGCCAG GTCTTCAAAG AGGGGTCAGC CTGGGGCAAA 2640
GCAGGACTGG GGGGAGGTGG GCAGCAGGGC CTATTCTGAG AATCACATAT TGTTACAGGC 2700
CTTGCACCCC CTTTGCTGCT TCCCTCCTGC TCATTTGGGG CTGCCACCAG CTCTCCACCC 2760
TCCTGGTTCC GCTGGCCGGG CCAAGAGAGG ATGGAGGGAT GGGAGTCCCA GGAGATCCTT 2820
GTAAATAGTG GGGTGGGACT GTTCTGAGTG ATCACCCGAG CACTTAAAGC TCCAGAGTCC 2880
CATTCTTCCT GGATGGAGCA GGTGGAGGTG CAGAGGGGAT TTCCTCCTCT CCTTCCTCCT 2940
GTCGAGAATT AACACCTCTC CACAGCCTTC CCCTCCAGAA CACCAGCCAG GGAGGGGTGG 3000
GGAAGGAGGT CACAGCCAAG AAAACTGCCC TGTGACGACT TCCCTCCTTC CCGCCTATGT 3060
GAGCCATCCT GAGATGTCTG TACAATAGAA ACCAAACCAA ATGGGCACCC TCGGTTGCCG 3120
GGGGGCAGGT GGGGAGGGGG GTGGGAAGAA GGGATGTCTG TCTGTCGTCC CCCTCCCCCT 3180
CTCCACTCTT TACCCACAAA GGCAGAAGAC TGTTACACTA GGGGGCTCAG CAAATTCAAT 3240
CCCACCCTTA CCAATTGAGC CAAACCTAGA AACAAACACA AAACACGAAT AGTGAGAGAC 3300
AAAATAGAGG AGAGAAAGAG AGCATGAGAG GGAGCGAGAC AGGCGACCAA CACAGAGGAG 3360
AGAAAACAAA AATAGCAAAA AAAAAAAAAA AAAGCAGTTC TTTATAATTT AATATTCTAT 3420 TTTAATAAAG GCGTTTATTA CCATATAAAT GTAGCAAAGA ACCTGGGCTA ATATGAA
Seq ID NO: B4 Protein sequence Protein Accession #: XP 044166.2
11 21 31 41 51
I I I I I
FCFAMPSLW SGIMERNGGF GELGCFGGSA KDRG LEDER ALQLADO C LLGLGEPPAP 60 RAGEDGGGGG GGAPAQPTAP PQPAPPPPPA APPAAPTTAP AAQTPQPPTA PKGASDAKLC 120 ALYKEAELRL KGSSNTTECV PVPTSEHVAE IVGRQGCKIK ALRAKTNTYI KTPVRGEEPV 180 FMVTGRREDV ATARREIISA AEHFSMIRAS RNKSGAAFGV APALPGQVTI RVRVPYRWG 240 WGPKGATI KRIQQQTNTY IITPSRDRDP VFEITGAPGN VERAREEIET HIAVRTGKIL 300 EYNNENDF A GSPDAAIDSR YSDA RVHQP GCKPLSTFRQ NSLGCIGECG VDSGFEAPRL 360 GEQGGDFGYG GY FPGYGVG KQDVYYGVAE TSPPLWAGQE NATPTSVLFS SASSSSSSSA 420 KARAGPPGAH RSPATSAGPE LAG PRRPPG EP QGFSK G GGG RSPGGG RDCMVCFESE VTAALVPCGH NLFCMECAVR ICERTDPECP VCHITATQAI RIFS
Seq ID NO: B5 DNA sequence
Nucleic Acid Accession #: NM.000909.1
Coding sequence: 209..1363
11 21 31 41 51
I I I I
CATTCCCACC CTTCCTTCTT TAATAAGCAG GAGCGAAAAA GACAAATTCC AAAGAGGATT 60
GTTCAGTTCA AGGGAATGAA GAATTCAGAA TAATTTTGGT AAATGGATTC CAATATCGGG 120
AATAAGAATA AGCTGAACAG TTGACCTGCT TTGAAGAAAC ATACTGTCCA TTTGTCTAAA 180
ATAATCTATA ACAACCAAAC CAATCAAAAT GAATTCAACA TTATTTTCCC AGGTTGAAAA 240
TCATTCAGTC CACTCTAATT TCTCAGAGAA GAATGCCCAG CTTCTGGCTT TTGAAAATGA 300
TGATTGTCAT CTGCCCTTGG CCATGATATT TACCTTAGCT CTTGCTTATG GAGCTGTGAT 360
CATTCTTGGT GTCTCTGGAA ACCTGGCCTT GATCATAATC ATCTTGAAAC AAAAGGAGAT 420
GAGAAATGTT ACCAACATCC TGATTGTGAA CCTTTCCTTC TCAGACTTGC TTGTTGCCAT 480
CATGTGTCTC CCCTTTACAT TTGTCTACAC ATTAATGGAC CACTGGGTCT TTGGTGAGGC 540
GATGTGTAAG TTGAATCCTT TTGTGCAATG TGTTTCAATC ACTGTGTCCA TTTTCTCTCT 600
GGTTCTCATT GCTGTGGAAC GACATCAGCT GATAATCAAC CCTCGAGGGT GGAGACCAAA 660
TAATAGACAT GCTTATGTAG GTATTGCTGT GATTTGGGTC CTTGCTGTGG CTTCTTCTTT 720
GCCTTTCCTG ATCTACCAAG TAATGACTGA TGAGCCGTTC CAAAATGTAA CACTTGATGC 780
GTACAAAGAC AAATACGTGT GCTTTGATCA ATTTCCATCG GACTCTCATA GGTTGTCTTA 840
TACCACTCTC CTCTTGGTGC TGCAGTATTT TGGTCCACTT TGTTTTATAT TTATTTGCTA 900
CTTCAAGATA TATATACGCC TAAAAAGGAG AAACAACATG ATGGACAAGA TGAGAGACAA 960
TAAGTACAGG TCCAGTGAAA CCAAAAGAAT CAATATCATG CTGCTCTCCA TTGTGGTAGC 1020
ATTTGCAGTC TGCTGGCTCC CTCTTACCAT CTTTAACACT GTGTTTGATT GGAATCATCA 1080
GATCATTGCT ACCTGCAACC ACAATCTGTT ATTCCTGCTC TGCCACCTCA CAGCAATGAT 1140
ATCCACTTGT GTCAACCCCA TATTTTATGG GTTCCTGAAC AAAAACTTCC AGAGAGACTT 1200
GCAGTTCTTC TTCAACTTTT GTGATTTCCG GTCTCGGGAT GATGATTATG AAACAATAGC 1260
CATGTCCACG ATGCACACAG ATGTTTCCAA AACTTCTTTG AAGCAAGCAA GCCCAGTCGC 1320
ATTTAAAAAA ATCAACAACA ATGATGATAA TGAAAAAATC TGAAACTACT TATAGCCTAT 1380
GGTCCCGGAT GACATCTGTT TAAAAACAAG CACAACCTGC AACATACTTT GATTACCTGT 1440
TCTCCCAAGG AATGGGGTTG AAATCATTTG AAAATGACTA AGATTTTCTT GTCTTGCTTT 1500
TTACTGCTTT TGTTGTAGTT GTCATAATTA CATTTGGAAC AAAAGGTGTG GGCTTTGGGG 1560
TCTTCTGGAA ATAGTTTTGA CCAGACATCT TTGAAGTGCT TTTTGTGAAT TTATGCATAT 1620
AATATAAAGA CTTTTATACT GTACTTATTG GAATGAAATT TCTTTAAAGT ATTACGATGC 1680
GCTGACTTCA GAAGTACCTG CCATCCAATA CGGTCATTAG ATTGGGTCAT CTTGATTAGA 1740
TTAGATTAGA TTAGATTGTC AACAGATTGG GCCATCCTTA CTTTATGATA GGCATCATTT 1800
TAGTGTGTTA CAATAGTAAC AGTATGCAAA AGCAGCATTC AGGAGCCGAA AGATAGTCTT 1860
GAAGTCATTC AGAAGTGGTT TGAGGTTTCT GTTTTTTGGT GGTTTTTGTT 1920
TTTTTTCACC TTAAGGGAGG CTTTCATTTC CTCCCGACTG ATTGTCACTT AAATCAAAAT 1980
TTAAAAATGA ATAAAAAGAC ATACTTCTCA GCTGCAAATA TTATGGAGAA TTGGGCACCC 2040
ACAGGAATGA AGAGAGAAAG CAGCTCCCCA ACTTCAAAAC CATTTTGGTA CCTGACAACA 2100
AGAGCATTTT AGAGTAATTA ATTTAATAAA GTAAATTAGT ATTGCTGCAA ATAGCTAAAT 2160
TATATTTATT TGAATTGATG GTCAAGAGAT TTTCCATTTT TTTTACAGAC TGTTCAGTGT 2220
TTGTCAAGCT TCTGGTCTAA TATGTACTCG AAAGACTTTC CGCTTACAAT TTGTAGAAAC 2280
ACAAATATCG TTTTCCATAC AGCAGTGCCT ATATAGTGAC TGATTTTAAC TTTCAATGTC 2340
CATCTTTCAA AGGAAGTAAC ACCAAGGTAC AATGTTAAAG GAATATTCAC TTTACCTAGC 2400
AGGGAAAAAT ACACAAAAAC TGCAGATACT TCATATAGCC CATTTTAACT TGTATAAACT 2460
GTGTGACTTG TGGCGTCTTA TAAATAATGC ACTGTAAAGA TTACTGAATA GTTGTGTCAT 2520
GTTAATGTGC CTAATTTCAT GTATCTTGTA ATCATGATTG AGCCTCAGAA TCATTTGGAG 2580
AAACTATATT TTAAAGAACA AGACATACTT CAATGTATTA TACAGATAAA GTATTACATG 2640
TGTTTGATTT TAAAAGGGCG GACATTTTAT TAAAATCAAT ATTGTTTTTG CTTTTTCTGA 2700
GGAGTCTCTT TCAGTTTCAT TTTTTCTCAT CCCATGACTT CCCTCCGATG GT
Seq ID NO: B6 Protein εequence Protein Accession #: NP 000900.1
MNSTLFSQVE NHSVHSNFSE KNAQLLAFEN DDCH PLAMI FT ALAYGAV IILGVSGN A 60 IIIILKQKE MRNVTNI IV N SFSD VA IMCLPFTFVY TLMDHWVFGE AMCKLNPFVQ 120
CVSITVSIFS LVLIAVERHQ IINPRG RP NNRHAYVGIA VIWVLAVASS LPFLIYQVMT 180
DEPFQNVTLD AYKDKYVCFD QFPSDSHRLS YTTL VLQY FGP CFIFIC YFKIYIRLKR 240
RNNMMDKMRD NKYRSSETKR INIML SIW AFAVCWLPLT IFNTVFDWNH QIIATCNHNL 300 F LCH TAM ISTCVNPIFY GF NKNFQRD LQFFFNFCDF RSRDDDYETI AMSTMHTDVS 360
KTSLKQASPV AFKKINNNDD NEKI
Seq ID NO: B7 DNA sequence
Nucleic Acid Accession #: NM_002590.2
Coding sequence: 204..3416
11 21 31 41 51
I I I I I
GCTTCTGTAA GAGACGGAGA GGCGCAGAGT GAGGGCGGGT CCGCGCGTCC TCAGAGCCCG 60 CTGGAGGCTC GGAGCTGCTA CCCGCAGACT TCTCCCGCAC AGGGCTCGCA AAGAGCGTGA 120 TTCCGAGAGC CTGAGACTGA CGCCCGACCT GGAAACCAGA GAAGACTTCC TTAGCCTTTC 180 GGATCGCACT TGAGGCTGGA GGCATGAGTC CTGTGAGGCG TTGGGGCAGC CCCTGCCTTT 240 TCCCCTTGCA GCTCTTCAGC CTCTGCTGGG TGCTCTCAGT GGCCCAGAGC AAAACAGTCC 300 GATACAGCAC CTTCGAGGAG GATGCCCCCG GCACGGTCAT CGGGACCCTG GCCGAGGACC 360 TGCATATGAA AGTATCGGGT GACACAAGCT TCCGCCTGAT GAAGCAATTC AACAGCTCTC 420 TGCTCCGGGT GCGCGAAGGC GACGGGCAGC TGACCGTCGG GGACGCCGGC CTGGACCGCG 480 AGCGGCTGTG TGGCCAGGCC CCGCAGTGCG TGCTGGCCTT CGATGTGGTC AGCTTCTCGC 540 AGGAGCAGTT CCGGCTGGTG CACGTGGAGG TAGAGGTGAG GGACGTCAAC GACCACGCGC 600
CGCGCTTCCC CAGGGCCCAG ATCCCGGTAG AGGTGTCCGA GGGTGCGGCA GTGGGCACGC 660
GCATCCCCTT GGAGGTGCCG GTGGACGAGG ACGTGGGCGC CAACGGGCTG CAGACCGTGC 720
GCCTGGCCGA GCCGCACAGC CCCTTTCGCG TGGAGCTGCA GACGCGAGCG GACGGCGCTC 780
AGTGCGCAGA CCTGGTGCTG CTGCAGGAGC TGGACCGCGA GAGCCAGGCC GCCTACAGCC 840
TGGAGCTGGT GGCCCAGGAC GGCGGCCGCC CGCCGCGCTC CGCCACGGCT GCCCTCAGCG 900
TGCGCGTCCT GGATGCGAAT GACCACAGCC CGGCCTTCCC GCAGGGCGCC GTGGCCGAAG 960
TGGAGCTGGC GGAAGACGCG CCCGTGGGCT CCCTGCTTCT CGACCTGGAC GCAGCCGACC 1020
CCGACGAGGG ACCTAACGGC GACGTGGTGT TCGCATTTGG CGCCCGCACC CCGCCGGAGG 1080 0 CGCGCCGCCT CTTTCGGCTT GACCCGCGAT CAGGCCGCCT CACCCTGGCC GGGCCCGTGG 1140
ACTACGAGCG TCAGGACACC TACGAGCTGG ACGTGCGGGC GCAGGACCGC GGACCCGGGC 1200
CCCGCGCTGC CACCTGCAAG GTCATCGTGC GCATCCGAGA CGTCAATGAC AACGCACCCG 1260
ACATCGCCAT CACCCCGCTG GCCGCCCCAG GCGCGCCGGC AACCTCACCC TTCGCCGCTG 1320
CCGCCGCCGC CGCTGCACTC GGGGGAGCGG ACGCTAGCTC GCCGGCGGGA GCCGGGACGC 1380 5 CGGAGGCTGG TGCCACTTCG CTGGTGCCGG AGGGGGCGGC GCGCGAGAGC CTGGTGGCCC 1440
TGGTCAGCAC CTCGGACAGG GACTCGGGCG CCAACGGGCA AGTGCGCTGC GCCCTCTATG 1500
GGCACGAGCA CTTCCGGCTG CAGCCGGCCT ACGCGGGCAG CTACCTGGTG GTGACCGCGG 1560
CGTCGCTGGA CCGCGAACGC ATCGCCGAGT ACAACTTGAC GCTGGTGGCC GAGGATCGCG 1620
GCGCGCCCCC GCTGCGCACA GTGCGGCCCT ACACGGTGCG TGTGGGCGAC GAGAACGACA 1680 0 ACGCGCCGCT CTTCACGCGG CCGGTCTATG AGGTGTCGGT GCGCGAGAAC AACCCGCCAG 1740
GCGCCTACCT GGCCACGGTG GCCGCCCGCG ACCGGGACCT GGGCCGCAAC GGCCAGGTCA 1800
CCTACCGGCT GCTGGAGGCC GAGGTGGGCC GCGCCGGGGG CGCCGTGTCC ACTTATGTCT 1860
CGGTGGACCC AGCTACCGGA GCCATCTACG CGCTGCGCAG CTTCGACTAT GAGACGCTGC 1920
GCCAACTCGA CGTTCGCATC CAAGCTAGCG ACGGCGGCTC CCCTCAGCTT TCCAGCAGCG 1980 5 CCCTAGTGCA AGTGCGCGTG CTGGACCAGA ACGACCATGC GCCAGTCCTG GTGCACCCGG 2040
CGCCAGCCAA TGGCTCCCTA GAAGTGGCGG TGCCTGGGCG CACCGCAAAG GACACGGTTG 2100
TGGCCCGTGT GCAGGCCCGG GATGCAGACG AGGGAGCCAA CGGGGAGCTG GCGTTCGAGC 2160
TGCAGCAGCA GGAGCCGCGC GAAGCCTTCG CCATCGGCCG CCGCACGGGG GAGATACTGC 2220
TCACCGGCGA CCTCTCGCAG GAGCCACCCG GTCGCGTGTT CAGGGCGCTC CTGGTCATAT 2280 0 CCGACGGCGG CCGTCCCCCG CTCACCACCA CCGCAACTGT CAGCTTCGTG GTAACAGCAG 2340
GGGGCGGGCG TGGGCCGGCT GCGCCTGCCA GTGCAGGAAG CCCGGAGCGT TCCCGCCCGC 2400
CTGGCTCTCG GCTCGGGGTG TCCGGGTCGG TGCTGCAATG GGACACGCCG CTGATCGTCA 2460
TCATCGTGCT GGCCGGGAGC TGCACGCTGC TGCTGGCCGC CATCATCGCC ATCGCCACCA 2520
CCTGCAACCG CCGCAAGAAG GAGGTGCGCA AAGGGGGGGC CCTCCGGGAA GAGCGGCCCG 2580 5 GGGCGGCGGG CGGCGGAGCC TCGGCTCCCG GCTCCCCGGA GGAGGCCGCC CGGGGAGCCG 2640
GGCCCAGGCC CAACATGTTC GACGTGCTCA CCTTCCCTGG CACCGGCAAA GCGCCCTTTG 2700
GCAGCCCCGC GGCGGACGCG CCTCCGCCTG CGGTCGCCGC GGCCGAAGTG CCGGGCTCAG 2760
AGGGCGGCAG CGCCACTGGG GAAAGCGCCT GTCACTTCGA GGGGCAGCAG CGGCTCCGCG 2820
GCGCGCACGC CGAGCCCTAC GGTGCCTCCC CGGGTTTTGG AAAGGAGCCG GCGCCCCCTG 2880 0 TGGCGGTGTG GAAAGGACAC TCCTTCAACA CCATTTCTGG CAGAGAA.GCA GAGAAGTTCA 2940
GCGGCAAAGA CAGCGGTAAA GGGGACAGTG ATTTCAACGA CAGCGATTCC GACATCAGCG 3000
GGGACGCTCT GAAAAAGGAT CTCATCAACC ACATGCAGAG TGGACTGTGG GCGTGCACCG 3060
CTGAGTGTAA GATCCTGGGC CACTCTGACC GCTGCTGGAG CCCATCCTGC AGCGGGCCCA 3120
ACGCACATCC ATCGCCTCAC CCACCAGCCC AGATGTCAAC CTTCTGTAAG AGCACGTCAC 3180 5 TGCCTCGGGA TCCTCTGCGC AGGGACAATT ACTACCAGGC CCAGCTGCCC AAGACAGTGG 3240
GGCTGCAGAG CGTCTATGAG AAAGTACTGC ACAGAGACTA TGACAGGACA GTCACTCTGC 3300
TCTCCCCTCC CCGTCCAGGG AGGCTCCCAG ACCTGCAGGA GATTGGAGTA CCCCTCTACC 3360
AGTCCCCTCC TGGCAGGTAC CTGTCCCCGA AGAAGGGAGC CAATGAAAAT GTGTAATCCC 3420
ATGCTGCATG TCTTCACACA TATACAGGTC ACTCCGAGAA GCCCCTAAGT TATTGACCGG 3480 0 TTTCAGTGTT GTATATATAA ATATGCAAGA TGTGCCTTAC AATGAAGTTG TTGGAAGCTA 3540
TTTCCAATCA CATTGGTACT GTTTGGTATT TGCAAACAAA AATGTAGTTA ATGTAATTTT 3600
TATGAAATGT GTGCAGTATT TAATTTTTCT TATGCTATTG ACTTTGATTT CAATTGCGGC 3660
TTGCCATTTT CTTAGTGTTT TTAACCTGTA CATTGTGTAA TGTAATGTTT GTATATAATG 3720
AAATTTTGTT ATATTTTTAT ATAATAAAAG CTAAAGTGGA AGTTATTGCC AAAGGAACTG 3780
55 TCTGTAAGAC AAAAAACAAA ACATGTTGGA ATTACTTAAT TGAAATTTAT CTTTCACCTG 3840
AAACAACCTA GTGTTTGAGA AATTTTGCCT TGCCAAGTAT AACTTGTATA TCTTGACTCT 3900
GTGGTAGATT TCAAGTTCAA TGTTATTTAA TTACATTTGG TTTTCCGTAA ACCGTGTCAC 3960
TTATAAGCAC AGTAATAAAA GATTTGTCAT GTGTTTGAAG AAAAAAAAAA AAAAAAAAAA 4020
AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAA
60
Seq ID NO: B8 Protein sequence , Protein Accession #: NP 002581.2
^ _ 1 11 21 31 41 51
65 i i i i i i
MSPVRRWGSP C FP Q FSL CWV SVAQSK TVRYSTFEED APGTVIGTLA EDLHMKVSGD 60
TSFRLMKQFN SSL RVREGD GQ TVGDAGL DRER CGQAP QCV AFDWS FSQEQFRLVH 120
VEVEVRDVND HAPRFPRAQI PVEVSEGAAV GTRIPLEVPV DEDVGANGLQ TVRLAEPHSP 180
FRVE QTRAD GAQCAD VLL, QE DRESQAA YSLELVAQDG GRPPRSATAA LSVRVLDAND 240
70 HSPAFPQGAV AEVE AEDAP VGSLL DtDA ADPDEGPNGD WFAFGARTP PEARRLFRLD 300
PRSGR T AG PVDYERODTY ELDVRAQDRG PGPRAATCKV IVRIRDVNDN APDIAITPLA 360
APGAPATSPF AAAAAAAALG GADASSPAGA GTPEAGATSL VPEGAARES VA VSTSDRD 420
SGANGQVRCA LYGHEHFRLQ PAYAGSYLW TAAS DRERI AEYN T VAE DRGAPPLRTV 480
RPYTVRVGDE NDNAP FTRP VYEVSVRENN PPGAYLATVA ARDRD GRNG QVTYRLLEAE 540
75 VGRAGGAVST YVSVDPATGA IYALRSFDYE T RQLDVRIQ ASDGGSPQ S SSALVQVRV 600
DQNDHAPV V HPAPANGSLE VAVPGRTAKD TWARVQARD ADEGANGELA FELQQQEPRE 660
AFAIGRRTGE I LTGDLSQE PPGRVFRA L VISDGGRPPL TTTATVSFW TAGGGRGPAA 720
PASAGSPERS RPPGSRLGVS GSVLQWDTPL IVIIV AGSC T L AAIIAI ATTCNRRKKE 780
VRKGGALREE RPGAAGGGAS APGSPEEAAR GAGPRPNMFD V TFPGTGKA PFGSPAADAP 840
80 PPAVAAAEVP GSEGGSATGE SACHFEGQQR L.RGAHAEPYG ASPGFGKEPA PPVAVWKGHS 900
FNTISGREAE KFSGKDSGKG DSDFNDSDSD ISGDALKKDL INHMQSGLWA CTAECKILGH 960
SDRC SPSCS GPNAHPSPHP PAQMSTFCKS TSLPRDPLRR DNYYQAQLPK TVGLQSVYEK 1020 V HRDYDRTV TLLSPPRPGR LPDLQEIGVP LYQSPPGRY SPKKGANENV Seq ID NO: B9 DNA sequence
Nucleic Acid Accession #: A 121939.12
Coding sequence: 185..1426
11 21 31 41 51
I I I I I
AGCGGAGTST CAGTGGCGAG CTCCGGGTGC TGTGGCCCGG CCTTGGCGGG GCGGCCTCCG 60
GCTCAGGCTG GCTGAGAGGC TCCCAGCTGC AGCGTCCCCG CCCGCCTCCT CGGGAGCTCT 120
GATCTCAGCT GACAGTGCCC TCGGGGACCA AACAAGCCTG GCAGGACAAA ATTAGAAGAT 180
CAAAATGGAA AATATGCTGC TTTGGTTGAT ATTTTTCACC CCTGGGTGGA CCCTCATTGA 240
TGGATCTGAA ATGGAATGGG ATTTTATGTG GCACTTGAGA AAGGTACCCC GGATTGTCAG 300
TGAAAGGACT TTCCATCTCA CCAGCCCCGC ATTTGAGGCA GATGCTAAGA TGATGGTAAA 360
TACAGTGTGT GGCATCGAAT GCCAGAAAGA ACTCCCAACT CCCAGCCTTT CTGAATTGGA 420
GGATTATCTT TCCTATGAGA CTGTCTTTGA GAATGGCACC CGAACCTTAA CCAGGGTGAA 480
AGTTCAAGAT TTGGTTCTTG AGCCGACTCA AAATATCACC ACAAAGGGAG TATCTGTTAG 540
GAGAAAGAGA CAGGTGTATG GCACCGACAG CAGGTTCAGC ATCTTGGACA AAAGGTTCTT 600
AACCAATTTC CCTTTCAGCA CAGCTGTGAA GCTTTCCACG GGCTGTAGTG GCATTCTCAT 660
TTCCCCTCAG CATGTTCTAA CTGCTGCCCA CTGTGTTCAT GATGGAAAGG ACTATGTCAA 720
AGGGAGTAAA AAGCTAAGGG TAGGGTTGTT GAAGATGAGG AATAAAAGTG GAGGCAAGAA 780
ACGTCGAGGT TCTAAGAGGA GCAGGAGAGA AGCTAGTGGT GGTGACCAAA GAGAGGGTAC 840
CAGAGAGCAT CTGCAGGAGA GAGCGAAGGG TGGGAGAAGA AGAAAAAAAT CTGGCCGGGG 900
TCAGAGGATT GCCGAAGGGA GGCCTTCCTT TCAGTGGACC CGGGTCAAGA ATACCCACAT 960
TCCGAAGGGC TGGGCACGAG GAGGCATGGG GGACGCTACC TTGGACTATG ACTATGCTCT 1020
TCTGGAGCTG AAGCGTGCTC ACAAAAAGAA ATACATGGAA CTTGGAATCA GCCCAACGAT 1080
CAAGAAAATG CCTGGTGGAA TGATCCACTT CTCAGGATTT GATAACGATA GGGCTGATCA 1140
GTTGGTCTAT CGGTTTTGCA GTGTGTCYGA CGAATCCAAT GATCTCCTTT ACCAATAYTG 1200
CGATGCTGAG TCGGGCTCCA CCGGTTCGGG GGTCTATCTG CGTCTGAAAG ATCCAGACAA 1260
AAAGAATTGG AAGCGCAAAA TCATTGCGGT CTACTCAGGG CACCAGTGGG TGGATGTCCA 1320
CGGGGTTCAG AAGGACTACA ACGTTGCTGT TCGCATCACT CCCCTAAAAT ACGCCCAGAT 1380
TTGCCTCTGG ATTCACGGGA ACGATGCCAA TTGTGCTTAC GGCTAACAGA GACCTGAAAC 1440
AGGGCGGTGT ATCATCTAAA TCACAGAGAA AACCAGCTCT GCTTACCGTA GTGAGATCAC 1500
TTCATAGGTT ATGCCTGGAC TTGAACTCTG TCAATAGCAT TTCWACATTT TTCAAAATCA 1560
GGAGATTTTC GTCCATTTAA AAAATGTATA GGTGCAGATA TTGAAACTAG GTGGGCACTT 1620
CAATGCCAAG TATATACTCT TCTTTACATG GTGATGAGTT TCATTTGTAG AAAAATTTTG 1680
TTGCCTTCTT AAAAATTAGA CACACTTTAA ACCTTCAAAC AGGTATTATA AATAACATGT 1740
GACTCCTTAA TGGACTTATT CTCAGGGTCC TACTCTAAGA AGAATCTAAT AGGATGCTGG 1800
TTGTGTATTA AATGTGAAAT YGCATAGATA AAGGTAGATG GTAAAGCAAT TAGTATCAGA 1860
ATAGAGACAG AAAGTTACAA CACAGTTTGT ACTACTCTGA GATGGAYCCA TTCAGCTCAT 1920
GCCCTCAATG TTTATATTGT GTTATCTGTT GGGTCTGGGA CATTTAGTTT AGTTTTTTTG 1980
AAGAATTACA AATCAGAAGA AAAAGCAAGC ATTATAAACA AAACTAATAA CTGTTTTACT 2040
GCTTTAAGAA ATAACAATTA CAATGTGTAT TATTTAAAAA TGGGAGAAAT AGTTTGTTCT 2100
ATGAAATAAA CCTAGTTTAG AAATAGGGAA GCTGAGACAT TTTAAGATCT CAAGTTTTTA 2160
TTTAACTAAT ACTCAAAATA TGGACTTTTC ATGTATGCAT AGGGAAGACA CTTCACAAAT 2220
TATGAATGAT CATGTGTTGA AAGCCACATT ATTTTATGCT ATACATTCTA TGTATGAGGT 2280
GCTACATTTT TAGGACAAAG AATTCTGTAA TCTTTTTCAA GAAAGAGTCT TTTTCTCCTT 2340
GACAAAATCC AGCTTTTGTA TGAGGACTAT AGGGTGAATT CTCTGATTAG TAATTTTAGA 2400
TATGTCCTTT CCTAAAAATG AATAAAATTT ATGAATATGA CTTAAAAAAA AAARWCGACG 2460
CGGCCGCGAA TTTAGTAGTA GTAGTCGACC CGGGAATTCC GGACCGGTAC CTGCAGGCGT 2520
ACCAGC
Seq ID NO: B10 Protein sequence Protein Accession ft: CAC35071.1
11 21 31 41 51 i I I I I I
MENML WLIF FTPGWTLIDG SEMEWDFMWH LRKVPRIVSE RTFHLTSPAF EADAKMMVNT 60 VCGIECQKEL PTPSLSELED YLSYETVFEN GTRTLTRVKV QDLV EPTQN ITTKGVSVRR 120 KRQVYGTDSR FSILDKRFLT NFPFSTAVKL STGCSGI IS PQHVLTAAHC VHDGKDYVKG 180 SKKLRVG LK MRNKSGGKKR RGSKRSRREA SGGDQREGTR EHLRERAKGG RRRKKSGRGQ 240 RIAEGRPSFQ WTRVKNTHIP KG ARGGMGD ATLDYDYA ELKRAHKKKY ME GISPTIK 300 KMPGGMIHFS GFDNDRADQ VYRFCSVSDE SNDL YQYCD AESGSTGSGV Y R KDPDKK 360 NWKRKIIAVY SGHQWVDVHG VQKDYNVAVR ITPLKYAQIC LWIHGNDANC AYG
Seq ID NO: 11 DNA sequence
Nucleic Acid Accession #: NM_002035.1
Coding sequence: 108..1106
51
AGGCGCCCGC CCGCCGCGCG TGATTCTCGC CTCGCCGCAG CCCAGCCCTG CGCGCCTTGC 60
CCGGCGGCCC CCGCCCGGCC GCTCCGGGCC CCTGGCCCCG CGGAGCGATG CTGCTGCTGG 120
CTGCCGCCTT CCTCGTGGCC TTCGTGCTGC TGCTGTACAT GGTGTCTCCG CTCATCAGCC 180
CCAAGCCCCT CGCCCTGCCC GGGGCGCATG TGGTGGTTAC AGGAGGTTCC AGTGGCATCG 240
GGAAGTGCAT TGCTATCGAG TGCTATAAAC AAGGAGCTTT TATAACTCTG GTTGCACGAA 300
ATGAGGATAA GCTGCTGCAG GCAAAGAAAG AAATTGAAAT GCACTCTATT AATGACAAAC 360
AGGTGGTGCT TTGCATATCA GTTGATGTAT CTCAAGACTA TAACCAAGTA GAGAATGTCA 420
TAAAACAAGC ACAGGAGAAA CTGGGTCCAG TGGACATGCT GGTAAATTGT GCAGGAATGG 480
CAGTGTCAGG AAAATTTGAA GATCTTGAAG TTAGTACCTT TGAAAGGTTA ATGAGCATCA 540
ATTACCTGGG CAGCGTGTAC CCCAGCCGGG CCGTGATCAC CACCATGAAG GAGCGCCGGG 600
TGGGCAGGAT CGTGTTTGTG TCCTCCCAGG CAGGACAGTT GGGATTATTC GGTTTCACAG 660
CCTACTCTGC ATCCAAGTTT GCCATAAGGG GATTGGCAGA AGCTTTGCAG ATGGAGGTGA 720
AGCCATATAA TGTCTACATC ACAGTTGCTT ACCCACCAGA CACAGACACA CCTGGCTTTG 780
CCGAAGAAAA CAGAACAAAG CCTTTGGAGA CTCGACTTAT TTCAGAGACC ACATCTGTGT 840
GCAAACCAGA ACAGGTGGCC AAACAAATTG TTAAAGATGC CATACAAGGA AATTTCAACA 900 GTTCCCTTGG CTCAGATGGβ TACATGCTCT CGGCCCTGAC CTGTGGGATG GCTCCAGTAA 960 CTTCTATTAC TGAGGGGCTC CAGCAGGTGG TCACCATGGG CCTTTTCCGC ACTATTGCTT 1020 TGTTTTACCT TGGAAGTTTT GACAGCATAG TTCGTCGCTG CATGATGCAG AGAGAAAAAT 1080 CTGAAAATGC AGACAAAACT GCCTAATCTT CTTACCCCTT GGAAGAAGAC TGTTTCCAAA 1140 TAATTTGAAC AGCTTGCTGC TAAATGGGAC CCAATTTTTG GCCTATAGAC ACTTATGTAT 1200 TGTTTTCGAA TACGTCAGAT TGGACCAGTG CTCTTCAGGA ATGTGGCTGC AAGCAAGGGG 1260 CTAGAAGTTC ACCTCCTGAC AGTATTATTA ATACTATGCA AATATGGAAT AGGAGACCAT 1320 TTGATTTTCT AGGCTTTGTG GTAGAGAGGT GAAGGTATGA GAATTAATAG CGTGTGAACA 1380 AAGTAAAGAA CAGGATTCCA GAATGATCAT TAAATTTGTT TCTATTTATT CTTTTTTGCC 1440 CCCCTAGAGA TTAAGTCCAG AAATGTACTT TCTGGCACAT AAAGAAATCT TGAGGACTTT 1500 GTTTAAACCT TCCATAAAAA AACAATTTTC GGTTTCTCGG GTTCTCTCTC TCTGTCTCTC 1560 TGTCTCTCTG TCTCTCTGTC TCTCTGTCTC TCTCTCTCTC TCTCTTTCTT TCTTTGTGTA 1620 TTTTATTCAA GATGAGTTGG ACCCATTGCC AGTGAGTCTG AATGTCACTG ACAGCCCTGT 1680 GTTGTGCTCA GGACTCACTC TGCTGCTGGT GGAAACTCAT GGCTTCTCTC TCTCTTTGAT 1740 CCCATAAAGC TACGAGGGGG ACGGGAGAGG GCAGTGCAAT GGGAAGTARA GAGATATTTT 1800 CCAGTAGGAA AAGCAATGCT TTCTTGTCTT TAGACTCAAA TGCTTAGGGA ACGTTTCATT 1860 TCTCATTCAT GGGGAAAGGC AGCCTCCTTA AATGTTTTCT GAAGAGCGGT AAAATCTAGA 1920 AGCTTAAGAA TTTACAGTTC CTTCAATAAC CATGATGACC TGAAGTTCAC CTATCCCATT 1980 TTAGCATCTA CTTGTTTTTC CCATCTCTTC CTTTCCAATT TTGCTTATAC TGCTGTAATA 2040 TTTTTGTAAA AAAAAAAAAA AAGGAAAAAA AAGACCAGCT AAAATTTTCG ACTTGACTTT 2100 TTAACTTAAC TCATGAATTA ATTAAAGCAA ATGAAAAAAT TAAAAAGTGT GACTTTTTCT 2160 CGGAGCATAT ATGTAGCTTT TAGGAAAGGC TGATGATGGT ATAAAGTTTG CTCATTAAGA 2220 AAAAAAGACA AGGCTGATTT TGAAGAGAGT TGCTTTTGAA ATAAAATGAT CA
Seq ID NO: B12 Protein sequence Protein Accession #: NP 002026.1
11
M AAAFLV AFVL LYMVS P ISPKPIiAL PGAHVWTGG SSGIGKCIAI ECYKQGAFIT 60 VARNEDK L QAKKEIE HS INDKQW CI SVDVSQDYNQ VENVIKQAQE KLGPVDMLVN 120
CAGMAVSGKF ED EVSTFER LMSINYLGSV YPSRAVITTM KERRVGRIVF VSSQAGQLGL 180
FGFTAYSASK FAIRGLAEAL QMEVKPYNVY ITVAYPPDTD TPGFAEENRT KP ETRLISE 240
TTSVCKPEQV AKQIVKDAIQ GNFNSSLGSD GYMLSALTCG MAPVTSITEG LQQWTMG F 300
RTIALFYLGS FDSIVRRCMM QREKSENADK TA
Seq ID NO: B13 DNA sequence
Nucleic Acid Accession it : CAT Cluster
60
Figure imgf000803_0001
120
TTTGGATTGG TTAAGTCCAA TTATTAAATG CTGCGGTTTC AAATTCCCAG CTGGAAGGAC 180
CACCCATTTA AAAACTTCAG AAGGCAGGAT CCTGCTCAAT TTATAAGGCT TTGGAAAATT 240
CCAGGCATTG GTTTGACATA TTTCCAGAGC TCAAATCTGC AGTGTTCCAC ATGCACATAC 300
AAGATCCAGA GTCTCATGTT AAAATCACTT ACATACCCAG AAAGACCACC ACTTTGCAGG 360
TATAATATTG TACTTAAAGA CAGAGAGGAA GTGTTTCTTA ATCCAAACAC ATGTACACCA 420
AAGAACACAT AAGATGCCTT CTTCCATCAA ATGCACTTGC TTGTGAATTA ATGGACTTGT 480
AAATGAAACA ATGCAATCAG TCTTTTATAA TGCACTGTTC AATTTGAGAT TCAAGTATTT 540
CTATTTCTTG GAAAAAATTT TAAGAATCAA AAATAAAGAA AATAAAAAGT GCATACAGTT 600
AAACATTCCA AAAAAAAAAA AA
Seq ID NO: B14 DNA sequence
Nucleic Acid Accession # : XM_086767.1
Coding sequence : 276 . .611
11 21 31 41 51
I I I I I
CTTGTTCATG GCATCTTTAG AAACAAACTG CAATTTTATT TCATTTCCTT GTCGTTCATA 60 CAAAGATTAC AAGACTAGCT TATGTGTGGA CTGTGACTGT TTTAAGGAAA AATCATGTCC 120 TCGGCTGGGT TATCAAGCCA AGCTATTTAA AGGTGTTTTA AAAGAAAGGA TGGAAGGAAG 180 ACCTCTTAGG ACCACTGTGT TTTTGGATAC AAGTGGTACA TATCCATTCT GTAGCCTATT 240 ATTTTGTTCT CAGTATAATT GTTCCAGATA AAACTATGAT GGATGGCTCG TTTTCATTTA 300 AATTATTAAA TCAGCTTGGA ATGATTGAAG AGCCAAGGCT TTATGAAAAG AACAAACCAT 360 TTTATAAACT TCAAGAAGTC AAGATTCTTG CTCAATTTTA TAATGACTTT GTAAATATTT 420 CAAGCATTGG TTTGACATAT TTCCAGAGCT CAAATCTGCA GTGTTCCACA TGCACATACA 480 AGATCCAGAG ACTCATGTTA AAATCACTTA CATACCCAGA AAGACCACCA CTTTGCAGGT 540 ATAATATTGT ACTTAAAGAC AGAGAGGAAG TGTTTCTTAA TCCAAACACA TGTACACCAA 600 AGAACACATA AGATGCCTTC TTCCATCAAA TGCACTTGCT TGTGAATTAA TGGACTTGTA 660 AATGAAACAA TGCAATCAGT CTTTTATAAT GCACTGTTCA ATTTGAGATT CAAGTATTTC 720 TATTTCTTGG AAAAAATTTT AAGAATCAAA AATAAAGAAA ATAAAAAATG CATACAGTTA 780 AACATTCC
Seq ID NO: B15 Protein sequence Protein Accession #: XP 086767.1 1 11 21 31 41 51 i i i i i i
MMDGSFSFKL NQLGMIEEP RLYEKNKPFY KLQEVKI AQ FYNDFVNISS IG TYFQSSN LQCSTCTYKI QRLM KS TY PERPPLCRYN IV KDREEVF LNPNTCTPKN T
Seq ID NO : B16 DNA sequence Nucleic Acid Accession #: CAT cluster 1 11 21 31
TTTTTTTTTT TTTTTTTTTT TTAAATGCAA AGGAGCAACA AAATTTATTG ACTGAATTAA 60
ACACAACAGT AAAATGGCAG TGTTGTAATT TCATTTTCAG ATGTTTGAAT GGAACAAGAA 120
AAGTGCTATT AGCCCAAGCT TCTTACATTC ATTAAAAGAG TGACTATCAA AAACAGCAAC 180
ATGCACAATG GTACATATGC ACAAAATGGA ATTATATCAA CAAATATACA AAATACCCAA 240
AATAAAATAT TTACAGGTTT AAAAATATAA ACATTGATTC CTCTATCCCA TTAAACCATT 300
GGAGTGGAGA AAGGAGGAAA GACCCTATTG CTATTTAGAA TCCTTTTTAA AACAAGTTTT 360
TAAAACATAG AATTAGTTCT AGGAGACAAT TTTTGATGTT TTTCAGGGGT TTAACATTCT 420
ATTATAAAAA TAACATCTAT AAACCTACTA ACAATTTTCC TCCTGTGCAC AAAAATAATA 480
CTGCCAAAAC CTGTCCTCAA AGACATGCCT GACTTTCAGG AAAGCTAATT ATGGAAATGG 540
AGTTTCTCGT TTGGGTTATC TTTGTTACTA TTTTCAAATA ACCAGCAACT CCCTATATTA 600
CACTGAGATA CTTTATATAA ATAACGTGGG CGAAACCTGA AGTTCACAAT GAGCCTGCTA 660
GGTAGCTGGT GTCAAGTACA AATGATAGGA ATTGACTTTG CCAACAACAT CAAAAGCATT 720
TTCCCTGATA TTCCTGATAG ACCTACCACT ATCAGATCCT CCATATTCAA TAAGATTTAT 780
CCTGGAAGCA ATGAAAATGT TAAATATTAC TTTGCTAGAG TTTCTCCTCC TTTATTTAGA 840
AATAAATGTG TAGTGGGGAC CAGTGGTTGT AATGTAGATA CTTGAGAAGT TTCATTGATT 900
CCTTCAGACC CATGCCG
Seq ID NO: B17 DNA sequence
Nucleic Acid Accession #: NM.022898.1
Coding sequence: 268..2739
11 21 31 41 51
I I I I I I
TTTTCTTGCT TTTCTTCCCT TTTTTTTCTT TTTGCAAACA AAACAAAAAA CAGCATAGAA 60 GAAAGAGCAA AATAAAGAAG AAGAAGAGGA GGAAGAGAGG GAAAGAGAGG AAGGGAAAAA 120 AAACACCAAC CCGGGCAGAG GAGGAGGTGC GGCGGCGGCG GCGGCGGCGG CAGCGGCGGC 180 AGCGGCGCGG CGGCGGCTCG GACCCCCTCC CCCGGCTCCC CCCATCAGTG CAGCTCTCCG 240 GGCGATGCCA GAATAGATGC CGGGGCAATG TCCCGCCGCA AACAGGGCAA CCCGCAGCAC 300 TTGTCCCAGA GGGAGCTCAT CACCCCAGAG GCTGACCATG TGGAGGCCGC CATCCTCGAA 360 GAAGACGAGG GTCTGGAGAT AGAGGAGCCA AGTGGCCTGG GGCTGATGGT GGGTGGCCCC 420 GACCCTGACC TGCTCACCTG TGGCCAGTGT CAAATGAACT TCCCCTTGGG GGACATCCTG 480 GTTTTTATAG AGCACAAAAG GAAGCAGTGT GGCGGCAGCT TGGGTGCCTG CTATGACAAG 540 GCCCTGGACA AGGACAGCCC GCCACCCTCC TCACGCTCCG AGCTCAGGAA AGTGTCCGAG 600 CCGGTGGAGA TCGGGATCCA AGTCACCCCC GACGAAGATG ACCACCTGCT CTCACCCACG 660 AAAGGCATCT GTCCCAAGCA GGAGAACATT GCAGGTAAAG ATGAGCCTTC CAGCTACATT 720 TGCACAACAT GCAAGCAGCC CTTCAACAGC GCGTGGTTCC TGCTGCAGCA CGCGCAGAAC 780 ACGCACGGCT TCCGCATCTA CCTGGAGCCC GGGCCGGCCA GCAGCTCGCT CACGCCGCGG 840 CTCACCATCC CGCCGCCGCT CGGGCCGGAG GCCGTGGCGC AGTCCCCGCT CATGAATTTC 900 CTGGGCGACA GCAACCCCTT CAACCTGCTG CGCATGACGG GCCCCATCCT GCGGGACCAC 960 CCGGGCTTCG GCGAGGGCCG CCTGCCGGGC ACGCCGCCTC TCTTCAGTCC CCCGCCGCGC 1020 CACCACCTGG ACCCGCACCG CCTCAGTGCC GAGGAGATGG GGCTCGTCGC CCAGCACCCC 1080 AGTGCCTTCG ACCGAGTCAT GCGCCTGAAC CCCATGGCCA TCGACTCGCC CGCCATGGAC 1140 TTCTCGCGGC GGCTCCGCGA GCTGGCGGGC AACAGCTCCA CGCCGCCGCC CGTGTCCCCG 1200 GGCCGCGGCA ACCCTATGCA CCGGCTCCTG AACCCCTTCC AGCCCAGCCC CAAGTCCCCG 1260 TTCCTGAGCA CGCCGCCGCT GCCGCCCATG CCCCCTGGCG GCACGCCGCC CCCGCAGCCG 1320 CCAGCCAAGA GCAAGTCGTG CGAGTTCTGC GGCAAGACCT TCAAGTTCCA GAGCAATCTC 1380 ATCGTGCACC GGCGCAGTCA CACGGGCGAG AAGCCCTACA AGTGCCAGCT GTGCGACCAC 1440 GCGTGCTCGC AGGCCAGCAA GCTCAAGCGC CACATGAAGA CGCACATGCA CAAGGCCGGC 1500 TCGCTGGCCG GCCGCTCCGA CGACGGGCTC TCGGCCGCCA GCTCCCCCGA GCCCGGCACC 1560 AGCGAGCTGG CGGGCGAGGG CCTCAAGGCG GCCGACGGTG ACTTCCGCCA CCACGAGAGC 1620 GACCCGTCGC TGGGCCACGA GCCGGAGGAG GAGGACGAGG AGGAGGAGGA GGAGGAGGAG 1680 GAGCTGCTAC TGGAGAACGA GAGCCGGCCC GAGTCGAGCT TCAGCATGGA CTCGGAGCTG 1740 AGCCGCAACC GCGAGAACGG CGGTGGTGGG GTGCCCGGGG TCCCGGGCGC GGGGGGCGGC 1800 GCGGCCAAGG CGCTGGCTGA CGAGAAGGCG CTGGTGCTGG GCAAGGTCAT GGAGAACGTG 1860 GGCCTAGGCG CACTGCCGCA GTACGGCGAG CTCCTGGCCG ACAAGCAGAA GCGCGGCGCC 1920 TTCCTGAAGC GTGCGGCGGG CGGClGGGGAC GCGGGCGACG ACGACGACGC GGGCGGCTGC 1980 GGGGACGCGG GCGCGGGCGG CGCGGTCAAC GGGCGCGGGβ GCGGCTTCGC GCCAGGCACC 2040 GAGCCCTTCC CCGGGCTCTT CCCGCGCAAG CCCGCGCCGC TGCCCAGCCC CGGGCTCAAC 2100 AGCGCCGCCA AGCGCATCAA GGTGGAGAAG GACCTGGAGC TGCCGCCCGC CGCGCTCATC 2160 CCGTCCGAGA ACGTGTACTC GCAGTGGCTG GTGGGCTACG CGGCGTCGCG GCACTTCATG 2220 AAGGACCCCT TCCTGGGCTT CACGGACGCA CGACAGTCGC CCTTCGCCAC GTCGTCCGAG 2280 CACTCGTCCG AGAACGGCAG CCTGCGCTTC TCCACGCCGC CCGGGGACCT GCTGGACGGC 2340 GGCCTCTCGG GCCGCAGCGG CACGGCCAGC GGAGGCAGCA CCCCGCACCT GGGCGGCCCG 2400 GGCCCCGGGC GGCCCAGCTC CAAGGAGGGC CGCCGCAGCG ACACGTGCGA GTACTGCGGC 2460 AAGGTGTTCA AGAACTGCAG CAACTTGACG GTGCACCGGC GGAGCCACAC CGGCGAGCGG 2520 CCTTACAAGT GCGAGCTGTG CAACTACGCG TGCGCGCAGA GCAGCAAGCT CACGCGCCAC 2580 ATGAAGACGC ACGGGCAGAT CGGCAAGGAG GTGTACCGCT GCGACATCTG CCAGATGCCC 2640 TTCAGCGTCT ACAGCACCCT GGAGAAACAC ATGAAAAAGT GGCACGGCGA GCACTTGCTG 2700 ACTAACGACG TCAAAATCGA GCAGGCCGAG AGGAGCTAAG CGCGCGGGCC CCGGCGCCCC 2760 GCACCTGTAC AGTGGAACCG TTGCCAACCG AGAGAATGCT GACCTGACTT GCCTCCGTGT 2820 CACCGCCACC CCGCACCCCG CGTGTCCCCG GGGCCCAGGG GAGGCGGCAC TCCAACCTAA 2880 CCTGTGTCTG CGAAGTCCTA TGGAAACCCG AGGGTTGATT AAGGCAGTAC AAATTGTGGA 2940 GCCTTTTAAC TGTGCAATAA TTTCTGTATT TATTGGGTTT TGTAATTTTT TTGGCATGTG 3000 CAGGTACTTT TTATTATTAT TTTTTCTGTT TGAATTCCTT TAAGAGATTT TGTTGGGTAT 3060 CCATCCCTTC TTTGTTTTTT TTTTAACCCG GTAGTAGCCT GAGCAATGAC TCGCAAGCAA 3120 TGTTAGAGGG GAAGCATATC TTTTAAATTA TAATTTGGGG GGAGGGGTGG TGCTGCTTTT 3180 TTGAAATTTA AGCTAAGCAT GTGTAATTTC TTGTGAAGAA GCCAACACTC AAATGACTTT 3240 TAAAGTTGTT TACTTTTTCA TTCCTTCCTT TTTTTTGTCC TGAAATAAAA AGTGGCATGC 3300 AGTTTTTTTT TTAATTATTT TTTAATTTTT TTTTTGGTTT TTGTTTTTGG GGTGGGGGGT 3360 GTGGATGTAC AGCGGATAAC AATCTTTCAA GTCGTAGCAC TTTGTTTCAG AACTGGAATβ 3420 GAGATGTAGC ACTCATGTCG TCCCGAGTCA AGCGGCCTTT TCTGTGTTGA TTTCGGCTTT 3480
CATATTACAT AAGGGAAACC TTGAGTGGTG GTGCTGGGGG AGGCACCCCA CAGACTCAGC 3540
GCCGCCAGAG ATAGGGTTTT TGGAGGGCTC CTCTGGGAAA TGGCCCGACA GCATTCTGAG 3600
GTTGTGCATG ACCAGCAGAT ACTATCCTGT TGGTGTGCCC TGGGGTGCCA TGGCTGCTAT 3660
TCGCTGTAGA TTAGGCTACA TAAAATGGGC TGAGGGTACC TTTTTGGGGA GATGGGGTGG 3720
CCTGCAGTGA CACAGAAAGG AAGAAACTAG CGGTGTTCTT TTAGGCGTTT TCTGGCTTGA 3780
CGGCTTCTCT CTTTTTTTAA ATCACCCCCA CCACATAAAT CTCAAATCCT ATGTTGCTAC 3840
AAGGGGTCAT CCATCATTTC CCAAGCAGAC GAATGCCCTA ATTAATTGAA GTTAGTGTTC 3900
TCTCATTTAA TGCACACTGA TGATATTGTA GGGATGGGTG GGGTGGGGAT CTTGCAAATT 3960
TCTATTCTCT TTTACTGAAA AAGCAGGGGA TGAGTTCCAT CAGAAGGTGC CCAGCGCTAC 4020
TTCCCAGGTT TTTATTTTTT TTTTCCTATC TCATTAGGTT GGAAGGTACT AAATATTGAA 4080
CTGTTAAGAT TAGACATTTG AATTCTGTTG ACCCGCACTT TAAAGCTTTT GTTTGCATTT 4140
AAATTAAATG GCTTCTAAAC AAGAAATTGC AGCATATTCT TCTCTTTGGC CCAGAGGTGG 4200
GTTAAACTGT AAGGGACAGC TGAGATTGAG TGTCAGTATT GCTAAGCGTG GCATTCACAA 4260
TACTGGCACT ATAAAGAACA AAATAAAATA ATAATTTATA GGACAGTTTT TCTACTGCCA 4320
TTCAATTTGA TGTGAGTGCC TTGAAAACTG ATCTTCCTAT TTGAGTCTCT TGAGACAAAT 4380
GCAAAACTTT TTTTTTGAAA TGAAAAGACT TTTTAAAAAA GTAAAACAAG AAAAGTACAT 4440
TCTTTAGAAA CTAACAAAGC CACATTTACT TTAAGTAAAA AAAAAAAAAA TTCTGGTTGA 4500
AGATAGAGGA TATGAAATGC CATAAGACCC AATCAAATGA AGAAATAAAC CCAGCACAAC 4560
CTTGGACATC CATTAGCTGA ATTATCCTCA GCCCCTTTTG TTTTTGGGAC AACGCTGCTT 4620
AGATATGGAG TGGAGGTGAT TTACTGCTGA ATTAAAACTC AAGTGACACA AGTTACAAGT 4680
TGATATCGTT GAATGAAAAG CAAAACAAAA ACAATTCAGG AACAACGGCT AATTTTTTCT 4740
AAAGTTAAAT TTAGTGCACT CTGTCTTAAA AATACGTTTA CAGTATTGGG TACATACAAG 4800
GGTAAAAAAA AAATTGTGTG TATGTGTGTT GGAGCGATCT TTTTTTTTCA AAGTTTGCTT 4860
AATAGGTTAT ACAAAAATGC CACAGTGGCC GCGTGTATAT TGTTTTCTTT TGGTGACGGG 4920
GTTTTAGTAT ATATTATATA TATTAAAATT TCTTGATTAC TGTAAAAGTG GACCAGTATT 4980
TGTAATAATC GAGAATGCCT GGGCATTTTA CAAAACAAGA AAAAAAATAC CCTTTTCTTT 5040
TCCTTGAAAA TGTTGCAGTA AAATTTAAAT GGTGGGTCTA TAAATTTGTT CTTGTTACAG 5100
TAACTGTAAA GTCGGAGTTT TAGTAAATTT TTTTCTGCCT TGGGTGTTGA ATTTTTATTT 5160
CAAAAAAAAT GTATAGAAAC TTGTATTTGG GGATTCAAAG GGGATTGCTA CACCATGTAG 5220
AAAAAGTATG TAGAAAAAAA GTGCTTAATA TTGTTATTGC TTTGCAGAAA AAAAAAAAAT 5280
CACATTTCTG ACCTGTACTT ATTTTTCTCT TCCCGCCTCC CTCTGGAATG GATATATTGG 5340
TTGGTTCATA TGATGTAGGC ACTTGCTGTA TTTTTACTGG AGCTCGTAAT TTTTTAACTG 5400
TAAGCTTGTC CTTTTAAAGG GATTTAATGT ACCTTTTTGT TAGTGAATTT GGAAATAAAA 5460
AGAAAAAAAA AACAAAAACA AACAGGCTGC CATAATATAT TTTTTTAATT TGGCAGGATA 5520
AAATATTGCA AAAAAAACAC ATTTGTATGT TAAGTCCTAT TGTACAGGAG AAAAAGGGTT 5580
GTTTGACAAC CTTTGAGAAA AAGAAACAAA AGGAAGTAGT TAAATGCTTT GGTTCACAAA 5640
TCATTTAGTT GTATATATTT TTTGTCGGAA TTGGCCTACA CAGAGAACCG TTCGTGTTGG 5700
GCTTCTCTCT GAACGCCCCG AACCTTGCAT CAAGGCTCCT TGGTGTGGCC ACAGCAGACC 5760
AGATGGGAAA TTATTTGTGT TGAGTGGAAA AAAATCAGTT TTTGTAAAGA TGTCAGTAAC 5820
ATTCCACATC GTCCTCCCTT TCTCTAAGAG GCCATCTCTA AGATGTCAGA TGTAGAGGAG S880
AGAGAGCGAG AGAACATCTT CCTTCTCTAC CATCACTCCT GTGGCGGTCA CCACCACCAC 5940
CTCTCCCGCC CTTACCAGCA GAAAGCAATG CAAACTGAGC TGCTTTAGTC CTTGAGAAAT 6000
TGTGAAACAA ACACAAATAT CATAAAAGGA GCTGGTGATT CAGCTGGGTC CAGGTGAAGT 6060
GACCTGCTGT TGAGACCGGT ACAAATTGGA TTTCAGGAAG GAGACTCCAT CACAGCCAGG 6120
ACCTTTCGTG CCATGGAGAG TGTTGGCCTC TTGTCTTTCT TCCCTGCTTT GCTGCTTTGC 6180
TCTCTGAAAC CTACATTCCG TCAGTTTCCG AATGCGAGGG CCTGGGATGA ATTTGGTGCC 6240
TTTCCATATC TCGTTCTCTC TCCTTCCCCT GCGTTTCCTC TCCATCCTTC ATCCTCCATT 6300
GGTCCTTTTT TTTTCTTTCA TTTTTTATTT AATTTCTTTT CTTCCTGTCT GTTCCTCCCC 6360
TAATCCTCTA TTTTATTTTT ATTTTTTGTA AAGCCAAGTA GCTTTAAGAT AAAGTGGTGG 6420
TCTTTTGGAT GAGGGAATAA TGCATTTTTA AATAAAATAC CAATATCAGG AAGCCATTTT 6480
TTATTTCAGG AAATGTAAGA AACCATTATT TCAGGTTATG AAAGTATAAC CAAGCATCCT 6540
TTTGGGCAAT TCCTTACCAA ATGCAGAAGC TTTTCTGTTC GATGCACTCT TTCCTCCTTG 6600
CCACTTACCT TTGCAAAGTT AAAAAAAAGG GGGGAGGGAA TGGGAGAGAA AGCTGAGATT 6660
TCAGTTTCCT ACTGCAGTTT CCTACCTGCA GATCCAGGGG CTGCTGTTGC CTTTGGATGC 6720
CCCACTGAGG TCCTAGAGTG CCTCCAGGGT GGTCTTCCTG TAGTCATAAC AGCTAGCCAG 6780
TGCTCACCAG CTTACCAGAT TGCCAGGACT AAGCCATCCC AAAGCACAAG CATTGTGTGT 6840
CTCTGTGACT GCAGAGAAGA GAGAATTTTG CTTCTGTTTT GTGTTTAAAA AACCAACACG 6900
GAAGCAGATG ATCCCGAGAG AGAGGCCTCT AGCATGGGTG ACCCAGCCGA CCTCAGGCCG 6960
GTTTCCGCAC TGCCACAACT TTGTTCAAAG TTGCCCCCAA TTGGAACCTG CCACTTGGCA 7020
TTAGAGGGTC TTTCATGGGG AGAGAAGGAG ACTGAATTAC TCTAAGCAAA ATGTGAAAAG 7080
TAAGGAAATC AGCCTTTCAT CCCGGTCCTA AGTAACCGTC AGCCGAAGGT CTCGTGGAAC 7140
ACAGGCAAAC CCGTGATTTT GGTGCTCCTT GTAACTCAGC CCTGCAAAGC AAAGTCCCAT 7200
TGATTTAAGT TGTTTGCATT TGTACTGGCA AGGCAAAATA TTTTTATTAC CTTTTCTATT 7260
ACTTATTGTA TGAGCTTTTG TTGTTTACTT GGAGGTTTTG TCTTTTACTA CAAGTTTGGA 7320
ACTATTTATT ATTGCTTGGT ATTTGTGCTC TGTTTAAGAA ACAGGCACTT TTTTTTATTA 7380
TGGATAAAAT GTTGAGATGA CAGGAGGTCA TTTCAATATG GCTTAGTAAA ATATTTATTG 7440
TTCCTTTATT CTCTGTACAA GATTTTGGGC CTCTTTTTTT CCTTAATGTC ACAATGTTGA 7500
GTTCAGCATG TGTCTGCCAT TTCATTTGTA CGCTTGTTCA AAACCAAGTT TGTTCTGGTT 7560 TCAAGTTATA AAAATAAATT GGACATTTAA CTTGATCTCC AAA
Seq ID NO: B18 Protein sequence Protein Accession ft: NP 075049.1
11 21 31 41 51
I I I I I
MSRRKQGNPQ HLSQREL1TP EADHVEAAIL EEDEG-EIEE PSGLG MVGG P 1DPD TCGQ 60 CQMNFP GDI LVFIEHKRKQ CGGS GACYD KADKDSPPP SSRSELRKVS EPVEIGIQVT 120 PDEDDH SP TKGICPKQEN IAGKDEPSSY ICTTCKQPFN SAWFL QHAQ NTHGFRIYLE 180 PGPASSS TP R TIPPPLGP EAVAQSP MN FLGDSNPFNL RMTGPI RD HPGFGEGR P 240 GTPP FSPPP RHHLDPHRLS AEEMG VAQH PSAFDRVMR NPMAIDSPAM DFSRR RELA 300 GNSSTPPPVS PGRGNPMHR NPFQPSPKS PF STPPLPP MPPGGTPPPQ PPAKSKSCEF 360 CGKTFKFQSN LIVHRRSHTG EKPYKCQ CD HACSQASK K RHMKTHMHKA GSLAGRSDDG 420 LSAASSPEPG TSE AGEG K AADGDFRHHE SDPS GHEPE EEDEEEEEEE EELL ENESR 480 PESSFSMDSE LSRNRENGGG GVPGVPGAGG GAAKALADEK ALV GKVMEN VG GALPQYG 540 ELLADKQKRG AF KRAAGGG DAGDDDDAGG CGDAGAGGAV NGRGGGFAPG TEPFPGLFPR 600 KPAP PSPG NSAAKRIKVE KD EIiPPAA IPSENVYSQW LVGYAASRHF MKDPF GFTD 660 ARQSPFATSS EHSSENGS R FSTPPGD LD GG SGRSGTA SGGSTPHLGG PGPGRPSSKE 720 GRRSDTCEYC GKVFKNCSN TVHRRSHTGE RPYKCELCNY ACAQSSKLTR HMKTHGQIGK 780 EVYRCDICQM PFSVYSTLEK HMKKWHGEHL LTNDVKIEQA ERS
Seq ID NO: B19 DNA sequence Nucleic Acid Accession # : NM_000399.2 Coding sequence : 339. .1769
1 11 21 31 51
I I I I
TAACTGAGCG AGGAGCAATT GATTAATAGC TCGGCGAGGG GACTCACTGA CTGTTATAAT 60 AACACTACAC CAGCAACTCC TGGCTTCCCA GCAGCCGGAA CACAGACAGG AGAGAGTCAG 120 TGGCAAATAG ACATTTTTCT TATTTCTTAA AAAACAGCAA CTTGTTTGCT ACTTTTATTT 180 CTGTTGATTT TTTTTTCTTG GTGTGTGTGG TGGTTGTTTT TAAGTGTGGA GGGCAAAAGG 240 AGATACCATC CCAGGCTCAG TCCAACCCCT CTCCAAAACG GCTTTTCTGA CACTCCAGGT 300 AGCGAGGGAG TTGGGTCTCC AGGTTGTGCG AGGAGCAAAT GATGACCGCC AAGGCCGTAG 360 ACAAAATCCC AGTAACTCTC AGTGGTTTTG TGCACCAGCT GTCTGACAAC ATCTACCCGG 420 TGGAGGACCT CGCCGCCACG TCGGTGACCA TCTTTCCCAA TGCCGAACTG GGAGGCCCCT 480 TTGACCAGAT GAACGGAGTG GCCGGAGATG GCATGATCAA CATTGACATG ACTGGAGAGA 540 AGAGGTCGTT GGATCTCCCA TATCCCAGCA GCTTTGCTCC CGTCTCTGCA CCTAGAAACC 600 AGACCTTCAC TTACATGGGC AAGTTCTCCA TTGACCCTCA GTACCCTGGT GCCAGCTGCT 660 ACCCAGAAGG CATAATCAAT ATTGTGAGTG CAGGCATCTT GCAAGGGGTC ACTTCCCCAG 720 CTTCAACCAC AGCCTCATCC AGCGTCACCT CTGCCTCCCC CAACCCACTG GCCACAGGAC 780 CCCTGGGTGT GTGCACCATG TCCCAGACCC AGCCTGACCT GGACCACCTG TACTCTCCGC 840 CACCGCCTCC TCCTCCTTAT TCTGGCTGTG CAGGAGACCT CTACCAGGAC CCTTCTGCGT 900 TCCTGTCAGC AGCCACCACC TCCACCTCTT CCTCTCTGGC CTACCCACCA CCTCCTTCCT 960 ATCCATCCCC CAAGCCAGCC ACGGACCCAG GTCTCTTCCC AATGATCCCA GACTATCCTG 1020 GATTCTTTCC ATCTCAGTGC CAGAGAGACC TACATGGTAC AGCTGGCCCA GACCGTAAGC 1080 CCTTTCCCTG CCCACTGGAC ACCCTGCGGG TGCCCCCTCC ACTCACTCCA CTCTCTACAA 1140 TCCGTAACTT TACCCTGGGG GGCCCCAGTG CTGGGGTGAC CGGACCAGGG GCCAGTGGAG 1200 GCAGCGAGGG ACCCCGGCTG CCTGGTAGCA GCTCAGCAGC AGCAGCAGCC GCCGCCGCCG 1260 CCGCCTATAA CCCACACCAC CTGCCACTGC GGCCCATTCT GAGGCCTCGC AAGTACCCCA 1320 ACAGACCCAG CAAGACGCCG GTGCACGAGA GGCCCTACCC GTGCCCAGCA GAAGGCTGCG 1380 ACCGGCGGTT CTCCCGCTCT GACGAGCTGA CACGGCACAT CCGAATCCAC ACTGGGCATA 1440 AGCCCTTCCA GTGTCGGATC TGCATGCGCA ACTTCAGCCG CAGTGACCAC CTCACCACCC 1500 ATATCCGCAC CCACACCGGT GAGAAGCCCT TCGCCTGTGA CTACTGTGGC CGAAAGTTTG 1560 CCCGGAGTGA TGAGAGGAAG CGCCACACCA AGATCCACCT GAGACAGAAA GAGCGGAAAA 1620 GCAGTGCCCC CTCTGCATCG GTGCCAGCCC CCTCTACAGC CTCCTGCTCT GGGGGCGTGC 1680 AGCCTGGGGG TACCCTGTGC AGCAGTAACA GCAGCAGTCT TGGCGGAGGG CCGCTCGCCC 1740
CTTGCTCCTC TCGGACCCGG ACACCTTGAG ATGAGACTCA GGCTGATACA CCAGCTCCCA 1800 AAGGTCCCGG AGGCCCTTTG TCCACTGGAG CTGCACAACA AACACTACCA CCCTTTCCTG 1860
TCCCTCTCTC CCTTTGTTGG GCAAAGGGCT TTGGTGGAGC TAGCACTGCC CCCTTTCCAC 1920
CTAGAAGCAG GTTCTTCCTA AAACTTAGCC CATTCTAGTC TCTCTTAGGT GAGTTGACTA 1980
TCAACCCAAG GCAAAGGGGA GGCTCAGAAG GAGGTGGTGT GGGGATCCCC TGGCCAAGAG 2040
GGCTGAGGTC TGACCCTGCT TTAAAGGGTT GTTTGACTAG GTTTTGCTAC CCCACTTCCC 2100
CTTATTTTGA CCCATCACAG GTTTTTGACC CTGGATGTCA GAGTTGATCT AAGACGTTTT 2160
CTACAATAGG TTGGGAGATG CTGATCCCTT CAAGTGGGGA CAGCAAAAAG ACAAGCAAAA 2220
CTGATGTGCA CTTTATGGCT TGGGACTGAT TTGGGGGACA TTGTACAGTG AGTGAAGTAT 2280
AGCCTTTATG CCACACTCTG TGGCCCTAAA ATGGTGAATC AGAGCATATC TAGTTGTCTC 2340
AACCCTTGAA GCAATATGTA TTATATACTC AGAGAACAGA AGTGCAATGT GATGGGAGGA 2400
ACGTAGCAAT ATCTGCTCCT TTTCGAGTTG TTTGAGAAAT GTAGGCTATT TTTTCAGTGT 2460
ATATCCACTC AGATTTTGTG TATTTTTGAT GTACCCACAC TGTTCTCTAA ATTCTGAATC 2520
TTTGGGAAAA AATGTAAAGC ATTTATGATC TCAGAGGTTA ACTTATTTAA GGGGGATGTA 2580
CATATTCTCT GAAACTAGGA . TGCATGCAAT TGTGTTGGAA GTGTCCTTGG TCGCCTTGTG 2640
TGATGTAGAC AAATGTTACA . AGGCTGCATG TAAATGGGTT GCCTTATTAT GGAGAAAAAA 2700
ATCACTCCCT GAGTTTAGTA . TGGCTGTATA TTTATGCCTA TTAATATTTG GAATTTTTTT 2760
TAGAAAGTAT ATTTTTGTAT GCTTTGTTTT GTGACTTAAA AGTGTTACCT TTGTAGTCAA 2820
ATTTCAGATA AGAATGTACA , TAATGTTACC GGAGCTGATT TGTTTGGTCA TTAGCTCTTA 2880
ATAGTTGTGA AAAAATAAAT CTATTCTAAC GCAAAACCAC TAACTGAAGT TCAGATATAA 2940
TGGATGGTTT GTGACTATAG 1 TGTAAATAAA TACTTTTCAA CAAT
Seq ID NO: B20 Protein sequence Protein Accession #: NP 000390.2
MMTAKAVDKI PVTLSGFVHQ LSDNIYPVED LAATSVTIFP NAE GGPFDQ MNGVAGDGMI 60
NIDMTGEKRS LD PYPSSFA PVSAPRNQTF TYMGKFSIDP QYPGASCYPE GIINIVSAGI 120
LQGVTSPAST TASSSVTSAS PNPLATGPLG VCTMSQTQPD LDH YSPPPP PPPYSGCAGD 180
LYQDPSAFLS AATTSTSSSL AYPPPPSYPS PKPATDPG F PMIPDYPGFF PSQCQRDLHG 240
TAGPDRKPFP CPLDTLRVPP PLTP STIRN FT GGPSAGV TGPGASGGSE GPRLPGSSSA 300
AAAAAAAAAY NPHHLPLRPI LRPRKYPNRP SKTPVHERPY PCPAEGCDRR FSRSDE TRH 360
IRIHTGHKPF QCRICMRNFS RSDH TTHIR THTGEKPFAC DYCGRKFARS DERKRHTKIH 420 RQKERKSSA PSASVPAPST ASCSGGVQPG GTLCSSNSSS LGGGP APCS SRTRTP
Seq ID NO: B21 DNA sequence
Nucleic Acid Accession # : NM_004962 .2
Coding sequence : 457 . .1893
11 21 31 CACACACGGG CGCACGCACA CGGCAGCCGG GCCAGGGACG ACCCTGTCAG CTGCAGCCCC 60
AGAGGTCCGG GGCGCGCAGC CGGGTCCCCT CGAGGGCGCA GCCGGCCGCC CCGCCCCGCC 120
CCTCGAAGCA GCCGGGCCGG GCGCGCAGTG GGCTACAAAC TTTCGCAGCG CGAGTCCGCC 180
AAGGCAGCGC GCCGACTCGG GCTCGGCTCG GCTCTGCGCT GCTCCGGACG GCTGTGACCG 240
CTGGCCGGGG GCTCGGGCCG CCGGTACCCA CGGACCGCGC GCCCGGGTGC CTGCTCCGCT 300
AAGCCCCTCG CCCCGCGCGG ACCTCGGTAT CCAGCGCCCT GCTGCCCGGG CTCTCCCCGC 360
GCGCCCTACT GCCGCGAGGT CAGTCCGCAG CCTCCGGTGC GCCAGCGCTC GCCTTCCTCC 420
TCCTGGACTT CGGCCCTTTG CCGCCCTCAC CACGCCATGG CTCATGTCCC CGCTCGGACC 480
AGCCCGGGAC CCGGGCCCCA GCTGCTGCTG CTGCTGCTGC CGTTGTTTCT GCTGTTGCTC 540
CGGGATGTGG CCGGCAGCCA CAGGGCCCCC GCCTGGTCCG CACTGCCCGC GGCCGCCGAC 600
GGCCTGCAGG GGGACAGGGA TCTCCAGCGG CACCCTGGGG ACGCGGCCGC CACGTTGGGC 660
CCCAGCGCCC AGGACATGGT CGCTGTCCAC ATGCACAGGC TCTATGAGAA GTACAGCCGG 720
CAGGGCGCGC GGCCGGGAGG GGGCAACACG GTCCGCAGCT TCAGGGCCAG GCTGGAAGTG 780
GTCGACCAGA AGGCCGTGTA TTTCTTCAAC CTGACTTCCA TGCAAGACTC GGAAATGATC 840
CTTACGGCCA CTTTCCACTT CTACTCAGAG CCGCCTCGGT GGCCTCGAGC GCTCGAGGTG 900
CTATGCAAGC CGCGGGCCAA GAACGCTTCA GGCCGCCCGC TGCCCCTGGG CCCGCCCACA 960
CGCCAGCACC TGCTCTTCCG CAGCCTCTCG CAGAACACGG CCACACAGGG GCTACTCCGC 1020
GGGGCCATGG CCCTGGCGCC CCCACCGCGC GGCCTGTGGC AGGCCAAGGA CATCTCCCCC 1080
ATCGTCAAGG CGGCCCGCCG GGATGGCGAG CTGCTCCTCT CCGCCCAGCT GGATTCTGAG 1140
GAGAGGGACC CGGGGGTGCC CCGGCCCAGC CCCTATGCGC CCTACATCCT AGTCTATGCC 1200
AACGATCTGG CCATCTCGGA GCCCAACAGC GTGGCAGTGA CGCTGCAGAG ATACGACCCC 1260
TTCCCTGCCG GAGACCCCGA GCCCCGCGCA GCCCCCAACA ACTCAGCGGA CCCCCGCGTG 1320
CGCCGAGCCG CGCAGGCCAC TGGGCCCCTC CAGGACAACG AGCTGCCGGG GCTGGATGAG 1380
AGGCCGCCGC GCGCCCACGC ACAGCACTTC CACAAGCACC AGCTGTGGCC CAGCCCCTTC 1440
CGGGCGCTGA AACCCCGGCC AGGGCGCAAA GACCGCAGGA AGAAGGGCCA GGAGGTGTTC 1500
ATGGCCGCCT CGCAGGTGCT GGACTTTGAC GAGAAGACGA TGCAGAAAGC CCGGAGGAAG 1560
CAGTGGGATG AGCCGAGGGT GTGCTCCCGG AGGTACCTGA AGGTGGACTT CGCAGACATC 1620
GGCTGGAATG AATGGATAAT CTCACCGAAA TCTTTTGATG CCTACTACTG CGCGGGAGCA 1680
TGTGAGTTCC CCATGCCTAA GATCGTTCGT CCATCCAACC ATGCCACCAT CCAGAGCATT 1740
GTCAGGGCTG TGGGCATCAT CCCTGGCATC CCAGAGCCCT GCTGTGTTCC CGATAAGATG 1800
AACTCCCTTG GGGTCCTCTT CCTGGATGAG AATCGGAATG TGGTTCTGAA GGTGTACCCC 1860
AACATGTCCG TGGACACCTG TGCCTGCCGG TGAGACCACT CCAGGGTGGA AAGAAGCCAC 1920
GCCCAGCAGA GCTGCCTTCT CGGAGCCTTC TGCAACCAGG ACTTGTGGTG CAGCTGCAGA 1980
CACAGAGCAC AGCTCATGGG CAACATCACT GGGGCCCAGA GAGAGCTGTC CGCCAGTGCA 2040
TCATTAGGGG GTCTTTCATT GCTAGTGACT AGCCCCTTAA ATGCCAGCCT GAGTACCTGA 2100
AGGAATCTGG GAATTAGCCC TGGCCTGAAA GTGGCCCATC ATTCATACCC ACTGTTCTGA 2160
AGGCTTGAAA ACAAAACATA TCCACAACAT TGGCTTGATG TGATCATCAT CTCATAACTG 2220
AGCAAGAAGA CTATGCAAAT CTTAGGGCGC TCGCTCCCTG CACACGGAAA GAACTCTGTT 2280
TAAATGCTCA GTTCAGAACA CTTTGGGCCA CATAGTGATT TTGGAAAACA GGATAATCGT 2340
GGTGTAAATG AGTGTTTCCT TTCAAAGTCC ACTGCAGAGC TTTTATCCAT ATGGTATGCA 2400
CATGTAGCCA ATATTGGTTT CTTTTTCTTA ATATATATAT TTTATTTTAA AACAACAAAA 2460
AGGGAGGGCG TTGACACCAT TCCCCACAGA GATAGTCATG CTGAGTGTGG GTTGTTTAAA 2520
CATGCATATT GAAATAACAC ATATAGTAAC GTGGGAATAC TAAAAAATAA CCAAGATTTT 2580
ATATTTTTGT AAATTATACT TTCTATACTG TAGATTGTGT ATGTTATGTG TTTTTATGGA 2640
AAGCTAATAA ATTAAAGGTA CAGTGGTATC TTGA
Seq ID NO: B22 Protein sequence Protein Accession #: NP 004953.1
11 21 31 41 51
I I I I I
MAHVPARTSP LPLF IΛ RD VAGSHRAPAW SALPAAADGL QGDRDLQRHP 60 GDAAATLGPS AQDMVAVHMH R YEKYSRQG ARPGGGNTVR SFRARLEWD QKAVYFFNLT 120 SMQDSEMI T ATFHFYSEPP RWPRALEVLC KPRAKNASGR PLPLGPPTRQ H LFRSLSQN 180 TATQGIΛRGA MAAPPPRG WQAKDISPIV KAARRDGELL LSAQLDSEER DPGVPRPSPY 240 APYI VYAND AISEPNSVA VT QRYDPFP AGDPEPRAAP NNSADPRVRR AAQATGPLQD 300 NE PGLDERP PRAHAQHFHK HQ WPSPFRA LKPRPGRKDR RKKGQEVFMA ASQVLDFDEK 360 TMQKARRKQW DEPRVCSRRY KVDFADIGW NEWIISPKSF DAYYCAGACE FPMPKIVRPS 420 NHATIQSIVR AVGIIPGIPE PCCVPDKMNS GVLFLDENR NWLKVYPNM SVDTCACR
Seq ID NO: B23 DNA sequence
Nucleic Acid Accession #: AK026322.1
1 11 21 31 41 51
1 1 | 1 | 1 1 | 1 | 1 ATTCTTTAAA TACTTAAACA TGGTTATAAC AGCTGTGTTT TAAGCTCCTT GTCTGTTAAT 60
TCCATCATCT GTCATTTTTG CATCTGTTTT TATTGACTAA CTTTCTTCCT CATCATGGTC 120
ACATATCCTT GCTTCTTCCC ATATTTAGTA AAGTTTAGTT GGATGCTGGA TTGTTTTAAT 180
TTAGCATTTT GGAGTGACTG CTTTTGCACT TGCCTTTAAA AGTATTGGAC TTCGTTTTGA 240
TAGTTGAATT ACTTGCAAAT CAGCTTGATC ATTCTGAGAC TTGTTTTTAA CTTTTGTCGA 300
AAAGGCTATG CTACTTCAAG TATAATAAAA CCTAGTTTTA GTTTTATCCT ATAACTAAGG 360
CATGTGTTCA ATTTGAATGT CTCCAACCCT GTGTGAACTC TGAAAATTGT TCAGCTCCCA 420
ATTTCGCAGT AATTTTTTTT GTTCAGCCTT GCAGTCTCAT CCTACTCAAG TGTGGCTCTG 480
TATCCAACAA CAGTCTTGGA GATCTCATGA AGATTTCTGA AACTTTTGCT CTGCAGGATA 540
CCTTCCTTTG TGGTTATGTG CCCTGAAAAC TCCAGCCTCC GTGTCTTCAA TTCAGTGAAA 600
CTACTACTCT GCTTGGATTC CCCTCTTATA CAATGGTCTA CCAAGTGACT GCAAACAGAA 660
ATCTAAGGGA ATTTCAGGAG TCACCTCATT TATTTTCCTT TTTTTCAGGG ATTATAGTAG 720
TACTATACCA CCTGTCAGCC AATGTGTGAG AATGGTGGTT TCATACATTT TCTCCAATTC 780
TTTCTTGTTA CAGGAGCCTC CATTACTTTT CAAACAGTAA TGCAGTTGCA GTTGCCTCTC 840
CTTTTCTTCA TTATGTGTTT ATCTCTGGCA GTTTGAGCCA AGAGAGGGCA CGGAGAAGTA 900
CAATGACTAG AGAGCACTTC TGTTGAGGCT CATTCATTGA CCCCTACCCC AGTGCTTTAT 960
GAATGTGTGC TGCAGATGTC ATACAGCATC ACAGCTTCTT CTCTAATTTA TGAGCCATAA 1020
TTTTTTTTTT TGTATTTTTA TTGTATTACC TGCTTGGTTG CAAGAGGATG ATGAGGAGGA 1080
CTACTATAGG ATAAATTTGT TTTTATAGAG CAATTTCTCA TGGGTCACGA GGGATAGTAC 1140 TCCATTTTCC TCACTGATAT CGGCTTGATC ATCTGAGTCA GTGGGCTCAT TGTGGAAACA 1200 TATGGAATCC TTTATGCTTT TTCTCAGGCT GCTTCTGTTA CATGAAATAA AGCCAGAGTT 1260 GATTGTGAAA AAAAAAAAAA AAAA
Seq ID NO: B24 DNA sequence
Nucleic Acid Accession #: cat cluster
1 11 21 31 41 51 1 1 J 1 | 1 1 | 1 1 TGTATACATT CCTTTCAAAT AAAGACCTTG AGAAAACAGC AGAGCCAAGT GAAGATCACC 60
TAAAGAACTT TGTGGCTAAT TTATACTTCA TGTAGTAGCA GTGGGTACTG GGCAGGGTCT 120
CTTTCCCACT CTGATGATTT GTGCTCTTAT TTTTCCTAGA TTTACCTCAT CTAGGGCATA 180
TTCTTTTCCC TCTTCCTCTT TACCTTTCCT GGTCCTGATC CCTCTGTACT CAGTTCCCCT 240
AAATTATTGG ACTACAAACT AATATACTAG AAAAGCATAC ACTTATTTTA TTTGAATGCA 300
GAAATGCTAT CTATCAGTAT ATATACATAA GAATGTATAT TACAGTATAT CTATATATAC 360
TTAACACTGT AACTTTCAGT ATTCCCCAGT TAGCGTACCT AACTCTCCTG TGGGTTATGT 420
TAATTCTTAT TAGACTACTA GAGAAAAACC AACTGGCAGT TTGCTAAGCA TATCTACTGG 480
TGTTGTTTCT GCGCCCTCTT TTGGCTAATT GATGTAATTA TACTGGCTCT AAAGATTTAC 540
TGCCCCATAA GTAAATAGTA TAGCCACATT CTGAACATAT CAAAAGTACA AACTTAGGAG 600
GAGTGTATGT ACAAAAATGT AAAATTTTAT GAAAATGAAC ATGTTTTTAT GATGTTATTT 660
CTAGTTCATA AGAATGTGAT GACTGCTTTG CTTCATTTAT GTACGTTCCC ATTATATTCT 720
TGCTGTCAAT CAATCACAAA TTTATATCAG ATTAGGATAA ACTAAGCCAT TTTATGTATT 780
TTATTTTAAA CCTTATTTTG GCAGAGTAAT TCCTTAGAAT TGGAAAAGCT GTTACTTTGA 840
AATTACCAAT TTATTACAAA ACATAGAAAT GTATTGTAGC TACAAAGACA ACCAAGCATT 900
TTCTGTGTTT TAATGAATAT CTAAAAAACT ACATTTAGTT TATTTTACTC AGTTTTGAAA 960
TGATTTTTTT ACTGGCTCTA TTGCCTTAAA ATAACTAAGA GATTAATGAT TCTTTGTATA 1020
ATTTTCCTTT TCTTTGTTCT TTTTTTTACA TTTCGCAGAG TTATATCTAT AGTTTTAGTA 1080
ACAATTTCTT ATGTATTCTG GATAACTGAA AACAACTAAA GGTGTTGGGC ATTAGAAAAT 1140
AATTGTGAGC AGTAAGATTA CTGATGTAAT ATGTATGTTG GACTGAAGTA TTTCTTTATA 1200
AACATTCTAT TTGATTTTAA GCAAAATGTA TGTTAAAGCA TGTTTTTACA TCAGTAAAGT 1260
CATTTGTCGA CCTTCTGGAA ATGAAAGGTT TTTACCTAGA TACTGTAAGT TACACCTCCT 1320
TAACAATCAT ATTTGTCATT GTTGTTTTCT GCAAACAAAA ATGTTTATGG GCTTCATGTA 1380
GGCTTAAGAT TGTAGGCAAA AATGGACTGA GTTCAGGACC CTTCAAGCAG TAGGCATTCA 1440
GTTACAGAGC AGTTGGTACT TTGTAACCCA GACTTACAGT TTAAAAATAT CAAGTTAGCT 1500
GATGTTTCAT TATAATAAAA ATACTATTTT GCTTAAGAGT TGTATTACAA ATATTTGTGC 1560
TTAACATTAG AAATAGCTGT TTTAAATTGT AGTTAACATA TTAACTTTTT CAGAAAAAAA 1620
GCATGGTTTA TTTTTAATAA TGAAATAGAG AACATAATAC GTAATGTTCA GTATA&CAGC 1680
TGAGTTAAAA CATCTGCCAG GATTAACATC AGTGCGTTTT TGCCAATGCA TAGAGGCATT 1740
TTTCTCTAAG TATGATGGCT AATGATAACT ATTCTTTGTT ACACATTCAA GTCACTCCCA 1800
TACAAGTAAC TAGTGGGTGA TATGTTTCAC TCCAAAGGGT GTATTAATTC TGAATGCTAA 1860
TCATGAAGAC TTAAGTTAGG ACAACACTTC AAACCAGGAA GTGTGAACTG ATTTA
Seq ID NO: B25 DNA sequence
Nucleic Acid Accession #: FGENESH predicted
Coding sequence: 1..1144
11 21 31 41 51
ATGGAGCGCG GGATGCACCT CGGTGCAGCG GCCGCCGGCG AGGACGACCT CTTCCTGCAC 60 AAGAGCCTGA GCGCCTCCAC CTCCAAGCGC TTGGAAGCGG CTTTCCGCTC CACGCCCCCG 120 GGCATGGACC TGTCCCTGGC GCCGCCGCCT CGGGAACGCC CGGCGTCCTC CTCCTCGTCG 180 CCCCTGGGCT GCTTCGAGCC GGCTGACCCC GAGGGGGCAG GGCTGCTGTT GCCGCCGCCT 240 GGAGGAGGCG GCGGCGGCAG CGCGGGAAGT GGCGGCGGCG GCGGCGGCGG GGTGGGTGTC 300 CCCGGGCTGC TAGTAGGTTC AGCCGGCGTT GGGGGCGACC CTAGCCTAAG CAGCCTGCCG 360 GCCGGGGCCG CCCTTTGCCT CAAGTACGGC GAAAGCGCGA GCCGGGGCTC GGTGGCCGAG 420 AGCAGCGGCG GCGAGCAGAG CCCCGACGAC GACAGCGACG GTCGCTGCGA GCTCGTGCTG 480 CGGGCCGGAG TAGCCGACCC GCGGGCCTCC CCGGGAGCGG GAGGTGGTGG CGCGAAGGCA 540 GCCGAGGGCT GCTCCAATGC CCACCTCCAC GGCGGCGCCA GCGTCCCCCC GGGGGGCCTG 600 GGCGGCGGCG GCGGCGGGGG TAGCAGCAGC GGTAGCAGTG GCGGCGGTGG CGGTAGCGGT 660 AGCGGCAGCG GCGGCAGCAG CAGCAGCAGC AGCAGCAGCA GCAAGAAATC CAAAGAGCAA 720 AAGGCGCTGC GGCTTAACAT CAATGCCCGA GAGCGCCGGC GGATGCACGA CCTGAACGAC 780 GCGCTGGACG AGCTGCGCGC GGTGATCCCC TACGCGCACA GCCCCTCGGT GCGAAAGCTC 840 TCCAAGATCG CCACGCTGCT GCTCGCCAAG AACTACATCC TCATGCAGGC GCAGGCCCTG 900 GAGGAGATGC GGCGCCTAGT CGCCTACCTC AACCAGGGCC AGGCCATCTC GGCTGCCTCC 960 CTGCCCAGCT CGGCGGCTGC AGCGGCAGCA GCTGCTGCCC TGCACCCGGC GCTCGGCGCC 1020 TACGAGCAGG CAGCCGGCTA CCCGTTCAGC GCCGGACTGC CCCCGGCTGC CTCCTGCCCG 1080 GAGAAGTGCG CCCTGTTTAA CAGCGTCTCC TCCAGCCTCT GCAAACAGTG CACGGAGAAG 1140 CCTT
Seq ID NO: B26 Protein sequence Protein Accession #: FGENESH predicted
11 21 31 41 51
I I I
MERGMHLGAA A 1AGEDD FLH KS SASTSKR EAAFRSTPP GMDLSLAPPP R 1ERPASSSSS 60 P GCFEPADP EGAGLLLPPP GGGGGGSAGS GGGGGGGVGV PG LVGSAGV GGDPS SS P 120 AGAALC KYG ESASRGSVAE SSGGEQSPDD DSDGRCE V RAGVADPRAS PGAGGGGAKA 180 AEGCSNAHLH GGASVPPGGL GGGGGGGSSS GSSGGGGGSG SGSGGSSSSS SSSSKKSKEQ 240 KALR NINAR ERRRMHD ND ADELRAVIP YAHSPSVRKL SKIATL LAK NYILMQAQAL 300 EEMRRLVAYL NQGQAISAAS LPSSAAAAAA AAAHPALGA YEQAAGYPFS AG PPAASCP 360 EKCA FNSVS SSLCKQCTEK P
Seq ID NO: B27 DNA sequence
Nucleic Acid Accession #: cat cluster 11 21 31 41 51
TTTTTTTTAA ATGTTTGATC AAAATATTTT AATAAAGATT CTTTCTGACA 60
TAGATACACA TACAAATGGT CGTACATAGC TGTCATAGTC TGATTGACCT ATTTAATATA 120 TATATCATTC TTTACACATC CAAAACCCGC CAACAGATCC ATCACAGCTC CCAACTCACC 180 ATCCAACCTG ACAAACTGAA TTTGTATTAT CTGCAAGGAG TGGAAAATAG CAGGACTCCA 240 TTTTTAAAAA AGATTTTCTT GATTTTCATA GGGCGGAAAG GCAGTCAAAC AGCCATGCAA 300 AACTAAAACT GAAAGCTCAC TTTGGGTAAA TAGCTTCTTG TTCTTCCTTA GTTTTCTTTC 360 TTTTTAAATT TTATTTTTTT AGAAAAATAA CAAAGGATTT CACACCATAG GCAAATCAAA 420 CCAGTCTTTT AACTTAAATA ATTCTCCACA GTTAAAATAA CATATATGTA CATATATATT 480 AAAAGCAATT AAATTAGACC TTTTAAAAAT GCACAGCACA GCCTGGAAAA ATATTTGCTT 540 AGCATGTTCT TACGTATAGC AACTATTGCT GTGATGTTTT TCCCTTTTGG AATGTAAAGG 600 AGTCCCCTTT CAAAAAAGAG ATCAATTCAT TCATCAATTA AGAATACACC TTTCCTGTAA 660 TTTTTGGACT GAAGCAATTT ATTAAAGCTC AATTTAAATA CAGGGATGAT GCAACTGAAA 720 ATATCCAGGT GACCTTTCAT AAACCTAAGC AGCTCAGATA CATCAATATT TCTCTTCATA 780 CTTGTTGGCA AATAAACCTT TAAACACTTG GCACACAGCA TAAGTAATCT ATAAAACAAT 840 TTTAGAGGCA TTAAAAAAAT CTGCACATAA GACCCATGAC TTTAACACAT GATAAATACT 900 GTTGATGTGG AAGGGTCATT GAAGAATAAC AAATAAATAC CATGAATTGT TAATACATCA 960 TTGCAGAGTA GAAAGTAACA AGGTGCACAT AAATATTTTT AAATGCAATT CTTTCAGCCA 1020 CAGTCAGTTT TTTTATATCA CTCTCGCCAA AACTTTGAGC ATTTTCACAG GATTAAAGTT 1080 CAGAGACAAT AAAAAATACA AGTCTTTCAT AGTAACATGT TCTCTCTCTC TCGCTCTGGG 1140 TTTTATTTCC CCCTCACTTA AGTCAACATT TCAAGTTTTT CTCCTGGCTC AGAATCAAAA 1200 TTTATTTTCA AGTGCCCTTT CTGATTTGTC TGAATGAATA TTCCATCTCT CATGCTACCG 1260 ATCCGCT
Seq ID NO: B28 DNA sequence
Nucleic Acid Accession #: NM.002581.2
Coding sequence: 368..5251
1 11 21 31 41 51
I 1 I I
GGGGGAGGGA ATTCAGCGGA TCAGTCTTAA GAGGAGCTTT TTTTTGGAGC GAGAAATCAT 60 ATAAAATAAA ATGAAATAAA ACAAGGAGGA AGGCAACCAG CTGTTAGGGG GAAAATAAGG 120 CAGATAAAGG AGCGGGGAGA GAAATTAATT GCCAACCAGG AGGAGTTGGG CTGTATTTTT 180 CAAAGGTGGG GAGAGTGGAG CACACACCTT GAGGAGGAAA GCGAGAAAGA AAAGAAAAAA 240 GCAAGTGAAG GGGGGCTCGC CCAAGAAGGG TGAAGAAGCG AAGAAAGTCG AGGCGCCGAG 300 GCTCCCAAAG CTGGCAGCTC CGGGTGGCGG TGCAGGGGCG AAGGGGGGGG CGGGGGGAAC 360 GTCGGACATG CGGCTCTGGA GTTGGGTGCT GCACCTGGGG CTGCTGAGCG CCGCGCTGGG 420 CTGCGGGCTG GCCGAGCGTC CCCGCCGGGC CCGGAGAGAC CCGCGGGCCG GCCGACCCCC 480 GCGCCCCGCC GCCGGCCCGG CCACCTGCGC CACCCGCGGC CCGCGGCCGC CGCGCCTCGC 540 CGCCGCCGCC GCCGCCGCCG GGCGTGCCTG GGAAGCCGTG CGCGTCCCCC GGCGGCGGCA 600 GCAGCGGGAG GCGAGGGGCG CCACCGAGGA GCCGAGCCCG CCGAGCCGGG CGCTCTATTT 660 CAGCGGGCGA GGCGAGCAGC TGCGAGTCCT CCGGGCCGAC CTCGAGCTGC CCCGGGACGC 720 GTTCACGCTG CAAGTGTGGC TGCGAGCGGA GGGGGGCCAG AGGTCTCCGG CAGTGATCAC 780 AGGGCTGTAT GACAAATGTT CTTATATCTC ACGTGACCGA GGATGGGTCG TGGGCATTCA 840 CACCATCAGT GACCAAGACA ACAAAGACCC ACGCTACTTT TTCTCCTTGA AGACAGACCG 900 AGCCCGGCAA GTGACCACCA TCAATGCCCA CCGCAGCTAC CTCCCAGGCC AGTGGGTATA 960 CCTAGCTGCC ACCTATGATG GGCAGTTCAT GAAGCTCTAT GTGAATGGTG CCCAGGTGGC 1020 CACCTCTGGG GAACAAGTGG GTGGCATATT CAGCCCACTG ACCCAGAAGT GCAAAGTGCT 1080 CATGTTAGGG GGCAGTGCCC TGAATCACAA CTACCGGGGC TACATCGAGC ACTTCAGTCT 1140 GTGGAAGGTG GCCAGGACTC AGCGGGAGAT ACTGTCTGAC ATGGAAACCC ATGGCGCCCA 1200 CACTGCTCTA CCTCAGCTCC TCCTCCAGGA GAACTGGGAC AATGTGAAGC ATGCCTGGTC 1260 CCCCATGAAG GATGGCAGCA GCCCCAAAGT GGAATTCAGC AATGCCCACG GCTTTCTGCT 1320 GGACACGAGT CTGGAGCCTC CTCTGTGCGG ACAGACATTG TGTGACAACA CAGAGGTCAT 1380 TGCCAGCTAC AATCAGCTCT CAAGTTTCCG CCAGCCCAAG GTGGTGCGCT ACCGCGTGGT 1440 CAACCTCTAT GAAGATGATC ATAAGAACCC GACGGTGACG CGCGAGCAGG TGGACTTCCA 1500 GCACCATCAG CTGGCTGAGG CCTTCAAGCA ATACAACATC TCCTGGGAGC TGGACGTGCT 1560 GGAGGTGAGC AACTCCTCCC TTCGCCGCCG CCTCATCCTG GCCAACTGTG ACATCAGCAA 1620 GATTGGGGAT GAGAACTGTG ACCCCGAGTG CAACCACACG CTGACGGGCC ACGACGGCGG 1680 GGATTGCCGC CACCTGCGCC ACCCTGCCTT CGTGAAGAAG CAGCACAACG GGGTGTGTGA 1740 CATGGACTGC AACTATGAAC GGTTCAACTT TGATGGTGGA GAGTGCTGTG ACCCTGAAAT 1800 CACCAATGTC ACTCAGACTT GCTTTGACCC CGACTCTCCA CACAGAGCCT ACTTGGATGT 1860 TAATGAGCTG AAGAACATTC TTAAATTGGA TGGATCAACA CATCTCAATA TTTTCTTTGC 1920 AAAATCCTCA GAGGAGGAGT TGGCAGGAGT AGCAACTTGG CCATGGGACA AGGAGGCCCT 1980 GATGCACTTA GGTGGCATTG TCTTGAACCC ATCTTTCTAT GGCATGCCTG GGCACACCCA 2040 CACCATGATC CATGAGATTG GTCACAGCCT GGGCCTCTAT CACGTCTTCC GAGGCATCTC 2100 AGAAATCCAG TCCTGCAGTG ACCCCTGCAT GGAGACAGAG CCCTCCTTCG AGACTGGAGA 2160 CCTCTGCAAT GATACCAACC CAGCCCCTAA ACACAAGTCC TGTGGTGACC CAGGGCCAGG 2220 AAATGACACC TGTGGCTTTC ATAGCTTCTT CAACACTCCT TACAACAACT TCATGAGCTA 2280 TGCAGATGAC GACTGTACGG ACTCCTTCAC GCCCAATCAA GTCGCCAGAA TGCACTGTTA 2340 CCTGGACCTG GTCTACCAGG GCTGGCAGCC CTCCAGGAAA CCAGCGCCTG TTGCCCTCGC 2400 CCCCCAAGTT CTGGGCCACA CAACGGACTC TGTGACACTG GAGTGGTTCC CACCTATAGA 2460 TGGCCATTTC TTTGAAAGAG AATTGGGATC AGCATGTCAT CTTTGCCTGG AAGGGAGAAT 2520 CCTGGTGCAG TATGCTTCCA ACGCTTCCTC CCCAATGCCC TGCAGCCCAT CAGGACACTG 2580 GAGCCCTCGT GAAGCAGAAG GTCATCCTGA TGTTGAACAG CCCTGTAAGT CCAGTGTCCG 2640 CACCTGGAGC CCAAATTCAG CTGTCAACCC ACACACGGTT CCTCCAGCCT GCCCTGAGCC 2700 TCAAGGCTGC TACCTCGAGC TGGAGTTCCT CTACCCCTTG GTCCCTGAGT CTCTGACCAT 2760 TTGGGTGACC TTTGTCTCCA CTGACTGGGA CTCTAGTGGA GCTGTCAATG ACATCAAACT 2820 GTTGGCTGTC AGTGGGAAGA ACATCTCCCT GGGTCCTCAG AATGTCTTCT GTGATGTCCC 2880 ACTGACCATC AGACTCTGGG ACGTGGGCGA GGAGGTGTAT GGCATCCAAA TCTACACGCT 2940 GGATGAGCAC CTGGAGATCG ATGCTGCCAT GTTGACCTCC ACTGCAGACA CCCCACTCTG 3000 TCTACAGTGT AAGCCCCTGA AGTATAAGGT GGTCCGGGAC CCTCCTCTCC AGATGGATGT 3060 GGCCTCCATC CTACATCTCA ATAGGAAATT CGTAGACATG GATCTAAATC TTGGCAGTGT 3120 GTACCAGTAT TGGGTCATAA CTATTTCAGG AACTGAAGAG AGTGAGCCAT CACCTGCTGT 3180
CACATACATC CATGGACGTG GGTACTGTGG CGATGGCATT ATACAAAAAG ACCAAGGTGA 3240
ACAATGCGAC GACATGAATA AGATCAATGG TGATGGCTGC TCCCTTTTCT GCCGACAAGA 3300
AGTCTCCTTC AATTGTATTG ATGAACCCAG CCGGTGCTAT TTCCATGATG GTGATGGGGT 3360
ATGTGAGGAG TTTGAACAAA AAACCAGCAT TAAGGACTGT GGTGTCTACA CGCCCCAGGG 3420
ATTCCTGGAT CAGTGGGCAT CCAATGCTTC AGTATCTCAT CAAGACCAGC AATGCCCAGG 3480
CTGGGTCATC ATCGGACAGC CAGCAGCATC CCAGGTGTGT CGAACCAAGG TGATAGATCT 3540
CAGTGAAGGC ATTTCCCAGC ATGCCTGGTA CCCTTGCACC ATCAGCTACC CATATTCCCA 3600
GCTGGCTCAG ACCACTTTTT GGCTCCGGGC GTATTTTTCT CAACCAATGG TTGCCGCAGC 3660
TGTCATTGTC CACCTGGTGA CGGATGGGAC ATATTATGGG GACCAAAAGC AGGAGACCAT 3720
CAGCGTGCAG CTGCTTGATA CCAAAGATCA GAGCCACGAT CTAGGCCTCC ATGTCCTGAG 3780
CTGCAGGAAC AATCCCCTGA TTATCCCTGT GGTCCATGAC CTCAGCCAGC CCTTCTACCA 3840
CAGCCAGGCG GTACGTGTGA GCTTCAGTTC GCCCCTGGTC GCCATCTCGG GGGTGGCCCT 3900
CCGTTCCTTC GACAACTTTG ACCCCGTCAC CCTGAGCAGC TGCCAGAGAG GGGAGACCTA 3960
CAGCCCTGCC GAGCAGAGCT GCGTGCACTT CGCATGTGAG AAAACTGACT GTCCAGAGCT 4020
GGCTGTGGAG AATGCTTCTC TCAATTGCTC CAGCAGCGAC CGCTACCACG GTGCCCAGTG 4080
TACTGTGAGC TGCCGGACAG GCTACGTGCT CCAGATACGG CGGGATGATG AGCTGATCAA 4140
GAGCCAGACG GGACCCAGCG TCACAGTGAC CTGTACAGAG GGCAAGTGGA ATAAGCAGGT 4200
GGCCTGTGAG CCAGTCGACT GCAGCATCCC AGATCACCAT CAAGTCTATG CTGCCTCCTT 4260
CTCCTGCCCT GAGGGCACCA CCTTTGGCAG TCAATGTTCC TTCCAGTGCC GTCACCCTGC 4320
ACAATTGAAA GGCAACAACA GCCTCCTGAC CTGCATGGAG GATGGGCTGT GGTCCTTCCC 4380
AGAGGCCCTG TGTGAGCTCA TGTGCCTCGC TCCACCCCCT GTGCCCAATG CAGACCTCCA 4440
GACCGCCCGG TGCCGAGAGA ATAAGCACAA GGTGGGCTCC TTCTGCAAAT ACAAATGCAA 4500
GCCTGGATAC CATGTGCCTG GATCCTCTCG GAAGTCAAAG AAACGGGCCT TCAAGACTCA 4560
GTGTACCCAG GATGGCAGCT GGCAGGAGGG AGCTTGTGTT CCTGTGACCT GTGACCCACC 4620
TCCACCAAAA TTCCATGGGC TCTACCAGTG TACTAATGGC TTCCAGTTCA ACAGTGAGTG 4680
TAGGATCAAG TGTGAAGACA GTGATGCCTC CCAGGGACTT GGGAGCAATG TCATTCATTG 4740
CCGGAAAGAT GGCACCTGGA ACGGCTCCTT CCATGTCTGC CAGGAGATGC AAGGCCAGTG 4800
CTCGGTTCCA AACGAGCTCA ACAGCAACCT CAAACTGCAG TGCCCTGATG GCTATGCCAT 4860
AGGGTCGGAG TGTGCCACCT CGTGCCTGGA CCACAACAGC GAGTCCATCA TCCTGCCAAT 4920
GAACGTGACC GTGCGTGACA TCCCCCACTG GCTGAACCCC ACACGGGTAG AGAGAGTTGT 4980
CTGCACTGCT GGTCTCAAGT GGTATCCTCA CCCTGCTCTG ATTCACTGTG TCAAAGGCTG 5040
TGAGCCCTTC ATGGGAGACA ATTATTGTGA TGCCATCAAC AACCGAGCCT TTTGCAACTA 5100
TGACGGTGGG GATTGCTGCA CCTCCACAGT GAAGACCAAA AAGGTCACCC CATTCCCTAT 5160
GTCCTGTGAC CTACAAGGTG ACTGTGCTTG TCGGGACCCC CAGGCCCAAG AACACAGCCG 5220
GAAAGACCTC CGGGGATACA GCCATGGCTA AGGAAGGACA AGAAGTTGTC AAAGAATTCC 5280
CAACGCCAGG ACCCACATCC CTTTGGTATT GATTTCACAG TCAGCTGCTC AACGGAATGG 5340
CCTCTCCACA CCAGGGATCC TTAGCACCCA ACCGGTCTGC CTTTAATTTT ACCCAGGAAG 5400
GACTCACATT GGGGCGAATG AACCAAGTTT CGCCATGCTG GATGATGAAA TGGATTCCCA 5460
TCCCAAAGTC TGAGATGGAT TGCATATACA GTGTGCAGTC CCAGAGCCTC CTAAAATTCT 5520
AGCCATTTGT CACACAACCA CAGCAAAAAA AAA
Seq ID NO: B29 Protein sequence Protein Accession #: NP 002572.1
11 21 31 41 51
I I I I I
MRLWS V HL GLLSAALGCG LAERPRRARR DPRAGRPPRP AAGPATCATR GPRPPR AAA 60 AAAAGRA EA VRVPRRRQQR EARGATEEPS PPSRA YFSG RGEQ RVLRA DLELPRDAFT 120 O RAEGG QRSPAVITGL YDKCSYISRD RGWWGIHTI SDQDNKDPRY FFSLKTDRAR 180 QVTTINAHRS Y PGQWVY A ATYDGQFMKL YVNGAQVATS GEOVGGIFSP TQKCKV ML 240 GGSA NHNYR GYIEHFSLWK VARTQREILS DMETHGAHTA LPQL LQEN DNVKHAWSPM 300 KDGSSPKVEF SNAHGF LDT SLEPPLCGQT CDNTEVIAS YNQLSSFRQP KWRYRWNL 360 YEDDHKNPTV TREQVDFQHH Q AEAFKQYN ISWELDVLEV SNSSLRRRLI J-ANCDISKIG 420 DENCDPECNH TLTGHDGGDC RHLRHPAFVK KQHNGVCDMD CNYERFNFDG GECCDPEITN 480 VTQTCFDPDS PHRAYLDVNE KNILKLDGS THLNIFFAKS SEEELAGVAT WPWDKEALMH 540 LGGIVUJPSF YGMPGHTHTM IHEIGHSLGL YHVFRGISEI QSCSDPCMET EPSFETGD C 600 NDTNPAPKHK SCGDPGPGND TCGFHSFFNT PYNNFMSYAD DDCTDSFTPN QVAR HCYD 660 LVYQGWQPSR KPAPVA APQ VLGHTTDSVT LEWFPPIDGH FFERE GSAC HLC EGRI V 720 QYASNASSPM PCSPSGHWSP REAEGHPDVE QPCKSSVRTW SPNSAVNPHT VPPACPEPQG 780 CY E EFLYP LVPESLTIWV TFVSTD DSS GAVNDIKL A VSGKNISLGP QNVFCDVPLT 840 IRLDVGEEV YGIQIYTLDE H EIDAAMLT STADTPLC Q CKPLKYKWR DPP QMDVAS 900 ILHNRKFVD MDLNLGSVYQ YWVITISGTE ESEPSPAVTY IHGRGYCGDG IIQKDQGEQC 960 DDMNKINGDG CSLFCRQEVS FNCIDEPSRC YFHDGDGVCE EFEQKTSIKD CGVYTPQGFL 1020 DQ ASNASVS HQDQQCPG V IIGQPAASQV CRTKVIDLSE GISQHA YPC TISYPYSQLA 1080 QTTFWLRAYF SQPMVAAAVI VHLVTDGTYY GDQKQETISV Q LODTKDQSH DLGLHVLSCR 1140 NNPLIIPWH DLSQPFYHSQ AVRVSFSSP VAISGVALRS FDNFDPVTLS SCQRGETYSP 1200 AEQSCVHFAC EKTDCPE AV ENASLNCSSS DRYHGAQCTV SCRTGYV QI RRDDELIKSQ 1260 TGPSVTVTCT EGKNKQVAC EPVDCSIPDH HQVYAASFSC PEGTTFGSQC SFQCRHPAQL 1320 KGNNSiTCM EDG WSFPEA LCE MCLAPP PVPNADLQTA RCRENKHKVG SFCKYKCKPG 1380 YHVPGSSRKS KKRAFKTQCT QDGSWQEGAC VPVTCDPPPP KFHGLYQCTN GFQFNSECRI 1440 KCEDSDASQG LGSNVIHCRK DGTWNGSFHV CQEMQGQCSV PNEIMSNLKL QCPDGYAIGS 1500 ECATSC DHN SESII PMNV TVRDIPHWLN PTRVERWCT AGLKWYPHPA IHCVKGCEP 1560 FMGDNYCDAI NNRAFCNYDG GDCCTSTVKT KKVTPFPMSC DLQGDCACRD PQAQEHSRKD 1620 LRGYSHG
Seq ID NO: B30 DNA sequence
Nucleic Acid Accession #: NM_032808.1
Coding sequence: 61..1008
11 21 31 41 51
I I I I I I
CTAGTCTATC TCCGCTTCCT CAACCTCTCC TACAACCCCA TCAGCACCAT TGAGGGCTCC 60 ATGTTGCATG AGCTGCTCCG GCTGCAGGAG ATCCAGCTGG TGGGCGGGCA GCTGGCCGTG 120 GTGGAGCCCT ATGCCTTCCG CGGCCTCAAC TACCTGCGCG TGCTCAATGT CTCTGGCAAC 180 CAGCTGACCA CACTGGAGGA ATTAGTCTTC CACTCGGTGG GCAACCTGGA GACACTCATC 240 CTGGACTCCA ACCCGCTGGC CTGCGACTGT CGGCTCCTGT GGGTGTTCCG GCGCCGCTGG 300 CGGCTCAACT TCAACCGGCA GCAGCCCACG TGCGCCACGC CCGAGTTTGT CCAGGGCAAG 360 GAGTTCAAGG ACTTCCCTGA TGTGCTACTG CCCAACTACT TCACCTGCCG CCGCGCCCGC 420 ATCCGGGACC GCAAGGCCCA GCAGGTGTTT GTGGACGAGG GCCACACGGT GCAGTTTGTG 480 TGCCGGGCCG ATGGCGACCC GCCGCCCGCC ATCCTCTGGC TCTCACCCCG AAAGCACCTG 540 GTCTCAGCCA AGAGCAATGG GCGGCTCACA GTCTTCCCTG ATGGCACGCT GGAGGTGCGC 600 TACGCCCAGG TACAGGACAA CGGCACGTAC CTGTGCATCG CGGCCAACGC GGGCGGCAAC 660 GACTCCATGC CCGCCCACCT GCATGTGCGC AGCTACTCGC CCGACTGGCC CCATCAGCCC 720 AACAAGACCT TCGCTTTCAT CTCCAACCAG CCGGGCGAGG GAGAGGCCAA CAGCACCCGC 780 GCCACTGTGC CTTTCCCCTT CGACATCAAG ACCCTCATCA TCGCCACCAC CATGGGCTTC 840 ATCTCTTTCC TGGGCGTCGT CCTCTTCTGC CTGGTGCTGC TGTTTCTCTG GAGCCGGGGC 900 AAGGGCAACA CAAAGCACAA CATCGAGATC GAGTATGTGC CCCGAAAGTC GGACGCAGGC 960 ATCAGCTCCG CCGACGCGCC CCGCAAGTTC AACATGAAGA TGATATGAGG CCGGGGCGGG 1020 GGGCAGGGAC CCCCGGGCGG CCGGGCAGGG GAAGGGGCCT GGCCGCCACC TGCTCACTCT 1080 CCAGTCCTTC CCACCTCCTC CCTACCCTTC TACACACGTT CTCTTTCTCC CTCCCGCCTC 1140 CGTCCCCTGC TGCCCCCCGC CAGCCCTCAC CACCTGCCCT CCTTCTACCA GGACCTCAGA 1200 AGCCCAGACC TGGGGACCCC ACCTACACAG GGGCATTGAC AGACTGGAGT TGAAAGCCGA 1260 CGAACCGACA CGCGGCAGAG TCAATAATTC AATAAAAAAG TTACGAACTT TCTCTGTAAC 1320 TTGGGTTTCA ATAATTATGG ATTTTTATGA AAACTTGAAA TAATAAAAAG AGAAAAAAAC 1380 TATTTCCTAT AGCTAGTCGG AATGCAAACT TTTGACGTCC TGATTGCTCC AGGGCCCTCT 1440 TCCAACTCAG TTTCTTGTTT TTCTCTTCCT CCTCCTCCTC TTCTTCCTCC TTTCTCTTCT 1500 CTTCCCCAGT GGGGAGGGAT CACTCAGGAA AACAGGAAAG GAGGTTCCAG CCCCACCCAC 1560 CTGCCCACCC CGCCCCAGGC ACCATCAGGA GCAGGCTAGG GGGCAGGCCT GGGCCCAGCT 1620 CCGGGCTGGC TTTTTGCAGG GCGCAGGTGG AGGGGACAGG TCTGCCGATG GGGGTGGGAG 1680 CCTGTCTGCT GGGCTGCCAG GCGGCACCAC TGCAAGGGGT GGGAGCCTGG CTTGGGTGTG 1740 GCTGAGACTC TGGACAGAGG CTGGGGTCCT CCTGGGGGAC AGCACAGTCA GTGGAGAGAG 1800 CCAGGGGCTG GAGGTGGGGC CCACCCCAGC CTCTGGTCCC AGCTCTGCTG CTCACTTGCT 1860 GTGTGGCCTC AAGCAGGTCA CTGGCCTCTC TGGGCCTCAG TCTCCACATC TGTACAAATG 1920 GGAACATTAC CCCCTGCCCT GCCTACCTCA CAGGGCTGTT GTGAGGAATT GATGAGATGA 1980 TGTATGTGAA ACACTTTGTA ACCTGTAAAG CGCTGTGCAC ACGTG
Seq ID NO: B31 Protein sequence Protein Accession tt: NP 116197.1
11 21 31
MLHE LRLQE IQ VGGQLAV VEPYAFRGLN YLRVLNVSGN Q TTLEELVF HSVGNLETLI 60 LDSNP ACDC RL VFRRRW RLNFNRQQPT CATPEFVQGK EFKDFPDV L PNYFTCRRAR 120 IRDRKAQQVF VDEGHTVQFV CRADGDPPPA ILWLSPRKH VSAKSNGR T VFPDGT EVR 180 YAQVQDNGTY LCIAANAGGN DSMPAH HVR SYSPD PHQP NKTFAFISNQ PGEGEANSTR 240 ATVPFPFDIK TLIIATTMGF ISF GW FC LVLLF SRG KGNTKHNIEI EYVPRKSDAG 300 ISSADAPRKF NMKMI
Seq ID NO: B32 DNA sequence
Nucleic Acid Accession #: CAT cluster
11 21 31 41 51
I I I I I
CAGCACATAC AAGAAACATA CAGTGTACCT CAAAAGGGGC CCTTGAAATG TCATCAAAGG 60 GTAATAACCT AGTGAGTGAG TTGTGATGTC ATCTGGAACA TAGGAAATGG GGCTCTTAGC 120 GTATTCGGTA CGAAGGAAGC CAGGCTGGTC CTGGCAGGAA GTAAATGATA ATCTTTGGGA 180 AACCAGGACC CTGCCTCCCA GCCCAGAGGT GGAGGAGGGC GGTCAGGGTG GGGTCTACAG 240 TGGCACAGCA CTGACAAAGG TAGAGGGAAA TGTAATAGCA CATCTACGCT GCAGTCTGGT 300 GAAAGTGGCC GGGGTGGTCC TTGGAAAACA GTTGGGCTGT TCTTGGCAGG AATTAGTGAC 360 AGCCTTTCCG TCACGGGCAG GGACGCCTTG ATTTAAAAAA AATAAATAAA TAAAACGTCT 420 GGGTATAGAA A
Seq ID NO: B33 DNA sequence
Nucleic Acid Accession #: NM.006174.1
Coding sequence: 71..1408
11 21 31 41 51
I I I I I
GAAAGGCTAT CGGTAACAAC TGACCTGCCA CAAAGTTAGA AGAAAGGATT GATTCAAGAA 60 AGACTATAAT ATGGATTTAG AGCTCGACGA GTATTATAAC AAGACACTTG CCACAGAGAA 120 TAATACTGCT GCCACTCGGA ATTCTGATTT CCCAGTCTGG GATGACTATA AAAGCAGTGT 180 AGATGACTTA CAGTATTTTC TGATTGGGCT CTATACATTT GTAAGTCTTC TTGGCTTTAT 240 GGGGAATCTA CTTATTTTAA TGGCTCTCAT GAAAAAGCGT AATCAGAAGA CTACGGTAAA 300 CTTCCTCATA GGCAATCTGG CCTTTTCTGA TATCTTGGTT GTGCTGTTTT GCTCACCTTT 360 CACACTGACG TCTGTCTTGC TGGATCAGTG GATGTTTGGC AAAGTCATGT GCCATATTAT 420 GCCTTTTCTT CAATGTGTGT CAGTTTTGGT TTCAACTTTA ATTTTAATAT CAATTGCCAT 480 TGTCAGGTAT CATATGATAA AACATCCCAT ATCTAATAAT TTAACAGCAA ACCATGGCTA 540 CTTTCTGATA GCTACTGTCT GGACACTAGG TTTTGCCATC TGTTCTCCCC TTCCAGTGTT 600 TCACAGTCTT GTGGAACTTC AAGAAACATT TGGTTCAGCA TTGCTGAGCA GCAGGTATTT 660 ATGTGTTGAG TCATGGCCAT CTGATTCATA CAGAATTGCC TTTACTATCT CTTTATTGCT 720 AGTTCAGTAT ATTCTGCCCT TAGTTTGTCT TACTGTAAGT CATACAAGTG TCTGCAGAAG 780 TATAAGCTGT GGATTGTCCA ACAAAGAAAA CAGACTTGAA GAAAATGAGA TGATCAACTT 840 AACTCTTCAT CCATCCAAAA AGAGTGGGCC TCAGGTGAAA CTCTCTGGCA GCCATAAATG 900 GAGTTATTCA TTCATCAAAA AACACAGAAG AAGATATAGC AAGAAGACAG CATGTGTGTT 960 ACCTGCTCCA GAAAGACCTT CTCAAGAGAA CCACTCCAGA ATACTTCCAG AAAACTTTGG 1020 CTCTGTAAGA AGTCAGCTCT CTTCATCCAG TAAGTTCATA CCAGGGGTCC CCACTTGCTT 1080 TGAGATAAAA CCTGAAGAAA ATTCAGATGT TCATGAATTG AGAGTAAAAC GTTCTGTTAC 1140 AAGAATAAAA AAGAGATCTC GAAGTGTTTT CTACAGACTG ACCATACTGA TATTAGTATT 1200
TGCTGTTAGT TGGATGCCAC TACACCTTTT CCATGTGGTA ACTGATTTTA ATGACAATCT 1260
TATTTCAAAT AGGCATTTCA AGTTGGTGTA TTGCATTTGT CATTTGTTGG GCATGATGTC 1320
CTGTTGTCTT AATCCAATTC TATATGGGTT TCTTAATAAT GGGATTAAAG CTGATTTAGT 1380 GTCCCTTATA CACTGTCTTC ATATGTAATA ATTCTCACTG TTT
Seq ID NO: B34 Protein sequence Protein Accession #: NP 006165.1
11 21 31 41 51
I I I I
MDLELDEYYN KT ATENNTA ATRNSDFPVW DDYKSSVDDL, QYFLIGLYTF VSL GFMGNL 60 LILMALMKKR NQKTTVNF I GN AFSDI V VLFCSPFTLT SV DQ MFG KVMCHIMPFL 120 QCVSVLVST ILISIAIVRY HMIKHPISNN LTANHGYF I ATVWTLGFAI CSP PVFHSL, 180 VELQETFGΞA LSSRY CVE SWPSDSYRIA FTIS L VQY ILPLVC TVS HTSVCRSISC 240 G SNKENR E ENEMINLT H PSKKSGPQVK LSGSHKWSYS FIKKHRRRYS KKTACV PAP 300 ERPSQENHSR I PENFGSVR SQLSSSSKFI PGVPTCFEIK PEENSDVHE RVKRSVTRIK 360 KRSRSVFYRL TILI VFAVS WMPLH FHW TDFNDN ISN RHFKLVYCIC HL GMMSCC 420 NPI YGFLNN GIKADVSLI HC HM
Seq ID NO: B35 DNA sequence
Nucleic Acid Accession #: NM_014279.1
Coding sequence: 286..1689
1 11 21 31 41
I I I I
GCGCGGGGGA GCCATTAGGA GGCGAGGAGA GAGGAGGGCG CAGCTCCCGC CCAGCCCAGC 60 CCTGCCCAGC CCTGCCCGGA GGCAGACGCG CCGGAACCGG GACGCGATAA ATATGCAGAG 120 CGGAGGCTTC GCGCAGCAGA GCCCGCGCGC CGCCCGCTCC GGGTGCTGAA TCCAGGCGTG 180 GGGACACGAG CCAGGCGCCβ CCGCCGGAGC CAGCGGAGCC GGGGCCAGAG CCGGAGCGCG 240 TCCGCGTCCA CGCAGCCGCC GGCCGGCCAG CACCCAGGGC CCTGCATGCC AGGTCGTTGG 300 AGGTGGCAGC GAGACATGCA CCCGGCCCGG AAGCTCCTCA GCCTCCTCTT CCTCATCCTG 360 ATGGGCACTG AACTCACTCA AGTGCTGCCC ACCAACCCTG AGGAGAGCTG GCAGGTGTAC 420 AGCTCTGCCC AGGACAGCGA GGGCAGGTGT ATCTGCACAG TGGTCGCCCC ACAGCAGACC 480 ATGTGTTCAC GGGATGCCCG CACAAAACAG CTGAGGCAGC TACTGGAGAA GGTGCAGAAC 540 ATGTCTCAAT CCATAGAGGT CTTGGACAGG CGGACCCAGA GAGACTTGCA GTACGTGGAG 600 AAGATGGAGA ACCAAATGAA AGGACTGGAG TCCAAGTTCA AACAGGTGGA GGAGAGTCAT 660 AAGCAACACC TGGCCAGGCA GTTTAAGGCG ATAAAAGCGA AAATGGATGA ACTTAGGCCT 720 TTGATACCTG TGTTGGAAGA GTACAAGGCC GATGCCAAAT TGGTATTGCA GTTTAAAGAG 780 GAGGTCCAGA ATCTGACGTC AGTGCTTAAC GAGCTGCAAG AGGAAATTGG CGCCTATGAC 840 TACGATGAAC TTCAGAGCAG AGTGTCCAAT CTTGAAGAAA GGCTCCGTGC ATGCATGCAA 900 AAACTAGCTT GCGGGAAGTT GACGGGCATC AGTGACCCCG TGACTGTCAA GACCTCCGGC 960 TCGAGGTTCG GATCCTGGAT GACAGACCCT CTCGCCCCTG AAGGCGATAA CCGGGTGTGG 1020 TACATGGACG GCTATCACAA CAACCGCTTC GTACGTGAGT ACAAGTCCAT GGTTGACTTC 1080 ATGAACACGG ACAATTTCAC CTCCCACCGT CTCCCCCACC CCTGGTCGGG CACGGGGCAG 1140 GTGGTCTACA ACGGTTCTAT CTACTTCAAC AAGTTCCAGA GCCACATCAT CATCAGGTTT 1200 GACCTGAAGA CAGAGACCAT CCTCAAGACC CGCAGCCTGG ACTATGCCGG TTACAACAAC 1260 ATGTACCACT ACGCCTGGGG TGGCCACTCG GACATCGACC TCATGGTGGA CGAGAGCGGG 1320 CTGTGGGCCG TGTACGCCAC CAACCAGAAC GCTGGCAACA TCGTGGTCAG TAGGCTGGAC 1380 CCCGTGTCCC TGCAGACCCT GCAGACCTGG AACACGAGCT ACCCCAAGCG CAGCGCCGGG 1440 GAGGCCTTCA TCATCTGCGG CACGCTGTAC GTCACCAACG GCTACTCAGG GGGTACCAAG 1500 GTCCACTATG CATACCAGAC CAATGCCTCC ACCTATGAAT ACATCGACAT CCCATTCCAG 1560 AACAAATACT CCCACATCTC CATGCTGGAC TACAACCCCA AGGACCGGGC CCTGTATGCC 1620 TGGAACAACG GCCACCAGAT CCTCTACAAC GTGACCCTCT TCCACGTCAT CCGCTCCGAC 1680 GAGTTGTAGC TCCCTCCTCC TGGAAGCCAA GGGCCCACGT CCTCACCACA AAGGGACTCC 1740 TGTGAAACTG CTGCCAAAAA GATACCAATA ACACTAACAA TACCGATCTT GAAAAATCAT 1800 CAGCAGTGCG GATTCTGACA TCGAGGGATG GCATTACCTC CGTGTTTCTC CCTTTCGAGC 1860 CGGCGGGCCA CAGACGTCGG AAGAAACTCC CGTATTTGCA GCTGGAACTG CAGCCCACGG 1920 CGCCCCGGTT TTCCTCCCCG CCCTGTCCCT CTCTGGTCAA ACAACATACT AAAGAGGCGA 1980 GGCAATGACT GTTGGCCAGT TCTCACCGGG GAAAAACCCA CTGTTAGGAT GGCATGAACA 2040 TTTCCTTAGA TCGTGGTCAG CTCCGAGGAA TGTGGCGTCC AGGCTCTTTG AGAGCCATGG 2100 GCTGCACCCG GCCGTAGGCT AGTGTAACTC GCATCCCATT GCAGTGCCGT TTCTTGACTG 2160 TGTTGCTGTC TCTTAGATTA ACCGTGCTGA GGCTCCACAT AGCTCCTGGA CCTGTGTCTA 2220 GTACATACTG AAGCGATGGT CAGAGTGTGT AGAGTGAAGT TGCTGTGCCC ACATTGTTTG 2280 AACTCGCGTA CCCCGTAGAT ACATTGTGCA ACGTTCTTCT GTTATTCCCT TGAGGTGGTA 2340 ACTTCGTATG TTCAGTTTAT GCGATGATTG TTGTAAATGC AATGCCGTAG TTTGGATTAA 2400 TAAGTGGATG GTTTTTGTTT CTAAAAAGAA AAAAAAAATC AGTGTTCACC CTTATAGAGA 2460 CATAGTCAAG TTCATGTTGA TAATAATCAA AGGAATTACT CTCTTCTTGT TAAATTAGCT 2520 AAATCATGTA ACCGCAGATA GGAAGGGCTC ACCTGGGGAA , ACTCTGGTTT CCGATGGGAC 2580 AGGAAAGTCA TACGGGCAAC AGTATGCGGA AAGTACGTTT TTTTAAGTAA AAAACAAAGG 2640 CAAACTTTGT ACTATCCAGT TATCTAAGGA ACAATAAAAA . CATTAGGAGA AAAAAAAAAA 2700 AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA. A
Seq ID NO: B36 Protein sequence Protein Accession #: NP 055094.1
11 21 31 41 51
I I I i I I
MPGRWRWQRD MHPARK LS LF I MGTEL TQVLPTNPEE SWQVYSSAQD SEGRCICTW 60 APQQTMCSRD ARTKQ RQLL EKVQNMSQSI EV DRRTQRD LQYVEKMENQ MKG ESKFKQ 120 VEESHKQH A RQFKAIKAKM DELRPLIPV EEYKADAK V LQFKEEVQN TSVLNELQEE 180 IGAYDYDELQ SRVSNLEERL RACMQKLACG KLTGISDPVT VKTSGSRFGS WMTDP APEG 240 DNRVWYMDGY HNNRFVREYK SMVDFMNTDN FTSHR PHPW SGTGQWYNG SIYFNKFQSH 300 IIIRFDLKTE TILKTRSLDY AGYNNMYHYA GGHSDID M VDESGLWAVY ATNQNAGNIV 360 VSRLDPVSLQ T QTWNTSYP KRSAGEAFII CGT YVTNGY SGGTKVHYAY QTNASTYEYI 420 DIPFQNKYSH ISM DYNPKD RAYANNGH QILYNVTLFH VIRSDE
Seq ID NO: B37 DNA sequence
Nucleic Acid Accession #: NM_006334.1
Coding sequence: 286..693
1 11 21 31 41 51
I I I I I I
GCGCGGGGGA GCCATTAGGA GGCGAGGAGA GAGGAGGGCG CAGCTCCCGC CCAGCCCAGC 60
CCTGCCCAGC CCTGCCCGGA GGCAGACGCG CCGGAACCGG GACGCGATAA ATATGCAGAG 120
CGGAGGCTTC GCGCAGCAGA GCCCGCGCGC CGCCCGCTCC GGGTGCTGAA TCCAGGCGTG 180
GGGACACGAG CCAGGCGCCG CCGCCGGAGC CAGCGGAGCC GGGGCCAGAG CCGGAGCGCG 240
TCCGCGTCCA CGCAGCCGCC GGCCGGCCAG CACCCAGGGC CCTGCATGCC AGGTCGTTGG 300
AGGTGGCAGC GAGACATGCA CCCGGCCCGG AAGCTCCTCA GCCTCCTCTT CCTCATCCTG 360
ATGGGCACTG AACTCACTCA AGTGCTGCCC ACCAACCCTG AGGAGAGCTG GCAGGTGTAC 420
AGCTCTGCCC AGGACAGCGA GGGCAGGTGT ATCTGCACAG TGGTCGCCCC ACAGCAGACC 480
ATGTGTTCAC GGGATGCCCG CACAAAACAG CTGAGGCAGC TACTGGAGAA GGTGCAGAAC 540
ATGTCTCAAT CCATAGAGGT CTTGGACAGG CGGACCCAGA GAGACTTGCA GTACGTGGAG 600
AAGATGGAGA ACCAAATGAA AGGACTGGAG TCCAAGTTCA AACAGGTGGA GGAGAGTCAT 660
AAGCAACACC TGGCCAGGCA GTTTAAGGGC TAACTTAAAA GAGTTTTTTC AATGCTGCAG 720
TGACTGAAGA AGCAGTCCAC TCCCATGTAA CCATGAAAGA GAGCCAGAGA GCTTTTTGCA 780
CCATGCATTT TTACTATTAT TTTCCAATAC TTAGCACCAT TTCACTAAGG AACCTTGAAT 840
ACAACCAGGA TCCTCCTTTG CATGCGACTG TAGCTGCATT TCATGAATAG TTTGAACCCT 900
TGTCAATGCA TTTTTTGAAA AAGAAAGAAA AAAAAAACTT CGTGTATGTG ACTCAAAGCA 960 TGTAACCTTA AGATGTTGCA TTCTAAACTG ACAATAAAGA CCTTTCCCC
Seq ID NO: B38 Protein sequence Protein Accession #: NP_006325.1
1 11 21 31 41 51
I I I I I I
MPGRWRWQRD MHPARKLLSL LFLILMGTEL TQVLPTNPEE S QVYSSAQD SEGRCICTW 60 APQQTMCSRD ARTKQLRQLL EKVQNMSQSI EVLDRRTQRD LQYVEKMENQ MKG ESKFKQ 120 VEESHKQHLA RQFKG
Seq ID NO: B39 DNA sequence
Nucleic Acid Accession #: NM.058199.1
Coding sequence: 286..795
1 11 21 31 41 51
I 1 I I I I
GCGCGGGGGA GCCATTAGGA GGCGAGGAGA GAGGAGGGCG CAGCTCCCGC CCAGCCCAGC 60
CCTGCCCAGC CCTGCCCGGA GGCAGACGCG CCGGAACCGG GACGCGATAA ATATGCAGAG 120
CGGAGGCTTC GCGCAGCAGA GCCCGCGCGC CGCCCGCTCC GGGTGCTGAA TCCAGGCGTG 180
GGGACACGAG CCAGGCGCCG CCGCCGGAGC CAGCGGAGCC GGGGCCAGAG CCGGAGCGCG 240
TCCGCGTCCA CGCAGCCGCC GGCCGGCCAG CACCCAGGGC CCTGCATGCC AGGTCGTTGG 300
AGGTGGCAGC GAGACATGCA CCCGGCCCGG AAGCTCCTCA GCCTCCTCTT CCTCATCCTG 360
ATGGGCACTG AACTCACTCA AAATAAAAGA GAAAACAAAG CAGAGAAGAT GGGAGGGCCA 420
GAGAGCGAGA GGAAGACCAC AGGAGAGAAG ACACTGAACG AGCTTCCCTT GTTTTGCCTG 480
GAAGCCCACG CTGGCTCCCT GGCTCTGCCC AGGATGTGCA GTCCAAATCC CAATCCAGCA 540
GTGGGGTTAT GTCGTCCCGC TTACCCTCAG AGCCCTTCTC CTGGTGCTGC CCAGACGATC 600
AGCCAGTCCC TCCTGGAGAG GTTCTGCATG GCCTCTAGGA GAGAAGTTTT CTTGGCCCCA 660
GGAAGGCCTG GTGGAGGGTG GTGGTTGTGC ACTGTTGCTG GACAGATGCA TTCATTCATG 720
TGCACACACA CACACACACA TGCACACACA GGGGAGCAGA TACCTGCAGA GAAGAGCCAA 780
CCAGGTCCTG ATTAGTGGCA AGCTGCCCCA CAAAGGGCTA TGCCTGTGTC TTATTGAGAC 840
ACCTTGGCAA AGAGATGGCT GATTCTGGGT GGTCCTGGAC ATGGCCGCAC CCAAGGGCCC 900
TCCAAGCCTT AATGGCACCC TGAAGCCTCC ATGCCCAGGC CAAAAGATGC TTTTCCTCCC 960 TAAAAAAAAA AAAAAAAAAA
Seq ID NO: B40 Protein sequence Protein Accession #: NP 478106.1 1 11 21 31 41 51 i i i i i i
MPGRWRWQRD MHPARKLLSL LFLILMGTEL TQNKRENKAE KMGGPESERK TTGEKTLNEL 60 PLFCLEAHAG SLALPRMCSP NPNPAVGLCR PAYPQSPSPG AAQTISQSLL ERFCMASRRE 120 VFLAPGRPGG GWWLCTVAGQ MHSFMCTHTH THAHTGEQIP AEKSQPGPD
Seq ID NO: B41 DNA sequence
Nucleic Acid Accession #: AY038071.1
Coding sequence: 1..1686
1 11 21 31 41 51
I I I I I I
ATGAGCAATC AGTACCAGGA GGAGGGCTGC TCCGAGAGGC CCGAGTGCAA AAGTAAATCT 60
CCAACTTTGC TCTCCTCCTA CTGCATCGAC AGCATCCTGG GCCGGAGGAG CCCGTGCAAA 120
ATGCGGTTGC TGGGAGCCGC GCAGAGCTTG CCTGCTCCGC TGACCAGCCG CGCCGACCCG 180
GAAAAGGCCG TGCAAGGCTC CCCTAAGAGC AGCAGCGCCC CGTTCGAGGC CGAGCTGCAC 240
CTGCCGCCCA AGCTGCGGCG CCTGTACGGC CCGGGCGGGG GCCGCCTCCT TCAGGGTGCG 300
GCAGCGGCGG CGGCGGCGGC GGCGGCGGCG GCGGCAGCGG CCGCCACGGC CACGGCGGGT 360
CCACGCGGGG AGGCCCCTCC GCCGCCACCG CCAACCGCGC GGCCCGGGGA ACGGCCGGAC 420
GGCGCAGGGG CCGCCGCGGC AGCCGCGGCC GCGGCCGCCG CGGCCTGGGA CACGCTCAAG 480
ATCAGCCAGG CGCCGCAGGT GAGCATCAGC CGCAGCAAGT CGTACCGCGA GAACGGGGCG 540 CCCTTCGTGC CGCCGCCGCC CGCGCTGGAC GAGCTGGGCG GCCCGGGGGG CGTCACGCAC 600 CCGGAGGAGC GCCTCGGCGT GGCCGGCGGC CCGGGCAGCG CCCCGGCTGC GGGTGGTGGC 660 ACCGGCACCG AGGACGACGA GGAGGAGCTG CTGGAGGACG AAGAAGATGA GGACGAGGAA 720 GAGGAACTGC TGGAGGACGA CGAGGAGGAG CTGCTGGAGG ACGACGCCCG CGCGCTGCTC 780 AAGGAGCCCC GGCGCTGTCC TGTGGCCGCC ACTGGCGCCG TGGCCGCAGC AGCTGCCGCT 840 GCAGTGGCCA CAGAGGGCGG GGAGCTGTCA CCCAAGGAGG AGCTGCTGCT GCACCCGGAA 900 GACGCTGAGG GCAAGGACGG CGAGGACAGC GTGTGCCTCT CTGCGGGCAG CGACTCGGAG 960 GAGGGGCTGC TGAAACGCAA ACAGAGGCGC TACCGCACCA CGTTCACCAG CTACCAGCTG 1020 GAGGAACTGG AGCGGGCCTT CCAGAAGACG CACTACCCGG ACGTCTTCAC CAGGGAGGAA 1080 CTGGCCATGA GGCTGGACTT GACCGAGGCC CGAGTCCAGG TCTGGTTCCA GAACCGTCGG 1140 GCCAAGTGGC GCAAGCGGGA GAAGGCAGGC GCGCAGACCC ACCCCCCTGG GCTGCCCTTC 1200 CCGGGGCCGC TCTCCGCCAC CCACCCGCTC AGCCCCTACC TGGACGCCAG CCCCTTCCCT 1260 CCGCACCACC CGGCGCTCGA CTCCGCTTGG ACTGCCGCTG CCGCCGCCGC CGCCGCCGCC 1320 TTCCCGAGCC TACCTCCGCC TCCGGGCTCG GCCAGCCTGC CGCCCAGCGG GGCGCCGCTG 1380 GGCCTGAGCA CTTTCCTCGG AGCGGCAGTG TTCCGACACC CAGCTTTCAT CAGCCCGGCA 1440 TTCGGCAGGC TCTTTTCCAC AATGGCCCCC CTGACCAGCG CGTCGACCGC GGCCGCGCTC 1500 CTGAGACAGC CCACACCCGC CGTGGAGGGC GCAGTGGCAT CGGGCGCCCT GGCCGACCCG 1560 GCCACGGCGG CCGCAGACAG ACGCGCCTCT AGCATAGCCG CGCTGAGGCT CAAGGCCAAG 1620 GAGCACGCGG CGCAGCTCAC GCAGCTCAAC ATCCTGCCGG GCACCAGCAC GGGCAAGGAG 1680 GTGTGC
Seq ID NO : B42 Protein sequence Protein Accession #: AAK93901.1
1 11 21 31 41 51
1 1 | 1 | 1 I 1 I 1
MSNQYQEEGC SERPECKSKS PTLLSSYCID SILGRRSPCK MRLLGAAQSL PAPLTSRADP 60
EKAVQGSPKS SSAPFEAELH LPPKLRRLYG PGGGRLLQGA AAAAAAAAAA AAAAATATAG 120
PRGEAPPPPP PTARPGERPD GAGAAAAAAA AAAAAWDTLK ISQAPQVSIS RSKSYRENGA 180
PFVPPPPALD ELGGPGGVTH PEERLGVAGG PGSAPAAGGG TGTEDDEEEL LEDEEDEDEE 240
EELLEDDEEE LLEDDARALL KEPRRCPVAA TGAVAAAAAA AVATEGGELS PKEELLLHPE 300
DAEGKDGEDS VCLSAGSDSE EGLLKRKQRR YRTTFTSYQL EELERAFQKT HYPDVFTREE 360
LAMRLDLTEA RVQVWFQNRR AKWRKREKAG AQTHPPGLPF PGPLSATHPL SPYLDASPFP 420
PHHPALDSAW TAAAAAAAAA FPSLPPPPGS ASLPPSGAPL GLSTFLGAAV FRHPAFISPA 480
FGRLFSTMAP LTSASTAAAL LRQPTPAVEG AVASGALADP ATAAADRRAS SIAALRLKAK 540
EHAAQLTQLN ILPGTSTGKE VC
Seq ID NO: B43 DNA sequence
Nucleic Acid Accession #: CAT cluster
CGCCTGCCCC CCCGTTGCTT CTCTCTCTTC CCTTCTGCCT GCGTGCTCGC CCGTCTTTGG 60
TTCCGCCGGT TCCGTGCGCC CTCTCTGGGC TTCGGCTTCA CCCTCCGTCT GGCTGTCGCT 120
CTGCTCTCCT CCGCTCTCAT GCCCCTTTCA GCTCCTACTC TGGTGTCGTC CCCCTCCCTC 180
GCTCGTTTCT CTTGTTCCTC TCCTTCCCGG TTCGTGTTCT GCTTCTTCGT GTTCCCTCTC 240
GTCTGTGTTT GTGGGTCGTC CTCTGCGTCC TGCCTCTTTC TCTTGCGTTT CCGCGCGCTT 300
CCTGTTTTGG TCCCCCTGGT TCTCGCGCGG TTCTGTGTGC GCGGGCCGCC CCGTTCTTTC 360
TTGGTGCTTT GCTCCTGCTC TCTGTCTGGT GTTCTCCGCC GTCTGTGTCT TTCTCCTTTT 420
ATCTTCTGTT TTCTCTTTTT CTTGTTTCTT CTTGTTTTTT TTTGTCTTTG TTTTCTCTTA 480
GCTGAGGTTG GGGAGAGATA ACGCTGTAAA CTTTTATTTT TCAGGAAATC TGGAAACCTA 540
CAGTCTCCAT GCCTGCTCAG CCAAGAAGGA GCTCACTGTG GGCACCAGAG ACAGGGACCC 600
AATGTGGAGA CCTGTGAGCC TGTGTCCGGC CCTGAACTCT CAAGCACAGG GCAGGCTTCC 660
TGAGCATTGA AGAGAATATG TGGGAGAACA AAACAGAAAC TGAAAGAATA TGCAAGGTGT 720
CTTTCTTGGA TGTTATTCCA TGATAGATAG TAGGGGCAGG AGTGAGAGAG GCTGACTAGG 780
TCTGGACATG GAGGCTGGAA GAGTCAGGGT GTGATTCGGA GAGGCGCATG AGAAGGAAGG 840
TGGATTTTAA GGCTGGAAAT CTGAGGGTCA GTGGTCCAAG TCACTCAGAG ACAGAATCAC 900
AGCATAGCCC TTGCTGATGG CAA
Seq ID NO: B44 DNA sequence
Nucleic Acid Accession #: NM_014421.1
Coding sequence: 718..1497
11 21 31 41 51
I I I I I
CCACGCGTCC GGCGGGAGCC CGCGGCGAGC GTAGCGCAAG TCCGCTCCCT AGGCATCGCT 60 GCGCTGGCAG CGATTCGCTG TCTCTTGTGA GTCAGGGGAC AACGCTTCGG GGCAACTGTG 120 AGTGCGCGTG TGGGGGACCT CGATTCTCTT CAGATCTCGA GGATTCGGTC CGGGGACGTC 180 TCCTGATCCC CTACTAAAGC GCCTGCTAAC TTTGAAAAGG AGCACTGTGT CCTGCAAAGT 240 TTGACACATA AAGGATAGGA AAAGAGAGGA GAGAAAAGCA ACTGAGTTGA AGGAGAAGGA 300 GCTGATGCGG GCCTCCTGAT CAATTAAGAG GAGAGTTAAA CCGCCGAGAT CCCGGCGGGA 360 CCAAGGAGGT GCGGGGCAAG AAGGAACGGA AGCGGTGCGA TCCACAGGGC TGGGTTTTCT 420 TGCACCTTGG GTCACGCCTC CTTGGCGAGA AAGCGCCTCG CATTTGATTG CTTCCAGTTA 480 TTGCAGAACT TCCTGTCCTG GTGGAGAAGC GGGTCTCGCT TGGGTTCCGC TAATTTCTGT 540 CCTGAGGCGT GAGACTGAGT TCATAGGGTC CTGGGTCCCC GAACCAGGAA GGGTTGAGGG 600 AACACAATCT GCAAGCCCCC GCGACCCAAG TGAGGGGCCC CGTGTTGGGG TCCTCCCTCC 660 CTTTGCATTC CCACCCCTCC GGGCTTTGCG TCTTCCTGGG GACCCCCTCG CCGGGAGATG 720 GCCGCGTTGA TGCGGAGCAA GGATTCGTCC TGCTGCCTGC TCCTACTGGC CGCGGTGCTG 780 ATGGTGGAGA GCTCACAGAT CGGCAGTTCG CGGGCCAAAC TCAACTCCAT CAAGTCCTCT 840 CTGGGCGGGG AGACGCCTGG TCAGGCCGCC AATCGATCTG CGGGCATGTA CCAAGGACTG 900 GCATTCGGCG GCAGTAAGAA GGGCAAAAAC CTGGGGCAGG CCTACCCTTG TAGCAGTGAT 960 AAGGAGTGTG AAGTTGGGAG GTATTGCCAC AGTCCCCACC AAGGATCATC GGCCTGCATG 1020 GTGTGTCGGA GAAAAAAGAA GCGCTGCCAC CGAGATGGCA TGTGCTGCCC CAGTACCCGC 1080 TGCAATAATG GCATCTGTAT CCCAGTTACT GAAAGCATCT TAACCCCTCA CATCCCGGCT 1140 CTGGATGGTA CTCGGCACAG AGATCGAAAC CACGGTCATT ACTCAAACCA TGACTTGGGA 1200
TGGCAGAATC TAGGAAGACC ACACACTAAG ATGTCACATA TAAAAGGGCA TGAAGGAGAC 1260
CCCTGCCTAC GATCATCAGA CTGCATTGAA GGGTTTTGCT GTGCTCGTCA TTTCTGGACC 1320
AAAATCTGCA AACCAGTGCT CCATCAGGGG GAAGTCTGTA CCAAACAACG CAAGAAGGGT 1380
TCTCATGGGC TGGAAATTTT CCAGCGTTGC GACTGTGCGA AGGGCCTGTC TTGCAAAGTA 1440
TGGAAAGATG CCACCTACTC CTCCAAAGCC AGACTCCATG TGTGTCAGAA AATTTGATCA 1500
CCATTGAGGA ACATCATCAA TTGCAGACTG TGAAGTTGTG TATTTAATGC ATTATAGCAT 1560
GGTGGAAAAT AAGGTTCAGA TGCAGAAGAA TGGCTAAAAT AAGAAACGTG ATAAGAATAT 1620
AGATGATCAC AAAAAGGGAG AAAGAAAACA TGAACTGAAT AGATTAGAAT GGGTGACAAA 1680
TGCAGTGCAG CCAGTGTTTC CATTATGCAA CTTGTCTATG TAAATAATGT ACACATTTGT 1740
GGAAAATGCT ATTATTAAGA GAACAAGCAC ACAGTGGAAA TTACTGATGA GTAGCATGTG 1800
ACTTTCCAAG AGTTTAGGTT GTGCTGGAGG AGAGGTTTCC TTCAGATTGC TGATTGCTTA 1860
TACAAATAAC CTACATGCCA GATTTCTATT CAACGTTAGA GTTTAACAAA ATACTCCTAG 1920
AATAACTTGT TATACAATAG GTTCTAAAAA TAAAATTGCT AAACAAGAAA TGAAAACATG 1980
GAGCATTGTT AATTTACAAC AGAAAATTAC CTTTTGATTT GTAACACTAC TTCTGCTGTT 2040
CAATCAAGAG TCTTGGTAGA TAAGAAAAAA ATCAGTCAAT ATTTCCAAAT AATTGCAAAA 2100
TAATGGCCAG TTGTTTAGGA AGGCCTTTAG GAAGACAAAT AAATAACAAA CAAACAGCCA 2160
CAAATACTTT TTTTTCAAAA TTTTAGTTTT ACCTGTAATT AATAAGAACT GATACAAGAC 2220
AAAAACAGTT CCTTCAGATT CTACGGAATG ACAGTATATC TCTCTTTATC CTATGTGATT 2280
CCTGCTCTGA ATGCATTATA TTTTCCAAAG TATACCCATA AATTGTGACT AGTAAAATAC 2340
TTACACAGAG CAGAATTTTC ACAGATGGCA AAAAAATTTA AAGATGTCCA ATATATGTGG 2400
GAAAAGAGCT AACAGAGAGA TCATTATTTC TTAAAGATTG GCCATAACCT GTATTTTGAT 2460
AGAATTAGAT TGGTAAATAC ATGTATTCAT ACATACTCTG TGGTAATAGA GACTTGAGCT 2520
GGATCTGTAC TGCACTGGAG TAAGCAAGAA AATTGGGAAA ACTTTTTCGT TTGTTCAGGT 2580
TTTGGCAACA CATAGATCAT ATGTCTGAGG CACAAGTTGG CTGTTCATCT TTGAAACCAG 2640
GGGATGCACA GTCTAAATGA ATATCTGCAT GGGATTTGCT ATCATAATNT TTCCTATGCN 2700
GNTGAATTCN GTGTGAGGTC CTGTGTCCGT CCTATCCTCA AATTATTTAT TTTATAGTGC 2760
TGAGATCCTC AAATAATCTC AATTTCGGAG GTTTCACAAA ATGGACTCCT GAAGTAGACA 2820
GAGTAGTGAG GTTTCATTGC CCTCTATAAG CTTCTGACTA GCCAATGGCA TCATCCAATT 2880
TTCTTCCCAA ACCTCTGCAG CATCTGCTTT ATTGCCAAAG GGCTAGTTTC GGTTTTCTGC 2940
CAGCCATTGC GGTTAAAAAA TATAAGTAGG ATAACTTGTA AAACCTGCAT ATTGCTAATC 3000
TATAGACACC ACAGTTTCTA AATTCTTTGA AACCACTTTA CTACTTTTTT TAAACTTAAC 3060
TCAGTTCTAA ATACTTTGTC TGGAGCACAA AACAATAAAA GGTTATCTTA TAGTTGTGAC 3120
TTTAAACTTT TGTAGACCAC AATTCACTTT TTAGTTTTCT TTTACTTAAA TCCCATCTGC 3180
AGTCTCAAAT TTAAGTTCTC CCAGTAGAGA TTGAGTTTGA GCCTGTATAT CTATTAAAAA 3240
TTTCAACTTC CCACATATAT TTACTAAGAT GATTAAGACT TACATTTTCT GCACAGGTCT 3300
GCAAAAACAA AAATTATAAA CTAGTCCATC CAAGAACCAA AGTTTGTATA AACAGGTTGC 3360
TATAAGCTTG GTGAAATGAA AATGGAACAT TTCAATCAAA CATTTCCTAT ATAACAATTA 3420
TTATATTTAC AATTTGGTTT CTGCAATATT TTTCTTATGT CCACCCTTTT AAAAATTATT 3480
ATTTGAAGTA ATTTATTTAC AGGAAATGTT AATGAGATGT ATTTTCTTAT AGAGATATTT 3540
CTTACAGAAA GCTTTGTAGC AGAATATATT TGCAGCTATT GACTTTGTAA TTTAGGAAAA 3600
ATGTATAATA AGATAAAATC TATTAAATTT TTCTCCTCTA AAAACTGAAA AAAAAAAAAA 3660 AAAAAAAAAA A
Seq ID NO: B45 Protein sequence Protein Accession #: NP_055236.1
1 11 21 31 41 51
I I I I I I
MAALMRSKDS SCCLLLLAAV LMVESSQIGS SRAKLNSIKS SLGGETPGQA ANRSAGMYQG 60
LAFGGSKKGK NLGQAYPCSS DKECEVGRYC HSPHQGSSAC MVCRRKKKRC HRDGMCCPST 120
RCNNGICIPV TESILTPHIP ALDGTRHRDR NHGHYSNHDL GWQNLGRPHT KMSHIKGHEG 180
DPCLRSSDCI EGFCCARHFW TKICKPVLHQ GEVCTKQRKK GSHGLEIFQR CDCAKGLSCK 240 VWKDATYSSK ARLHVCQKI
Seq ID NO: 46 DNA sequence
Nucleic Acid Accession #: NM_019885.1
Coding sequence: 1..1539
1 11 21 31 41 51
I I I I I I
ATGCTCTTTG AGGGCTTGGA TCTGGTGTCG GCGCTGGCCA CCCTCGCCGC GTGCCTGGTG 60
TCCGTGACGC TGCTGCTGGC CGTGTCGCAG CAGCTGTGGC AGCTGCGCTG GGCCGCCACT 120
CGCGACAAGA GCTGCAAGCT GCCCATCCCC AAGGGATCCA TGGGCTTCCC GCTCATCGGA 180
GAGACCGGCC ACTGGCTGCT GCAGGGTTCT GGCTTCCAGT CGTCGCGGAG GGAGAAGTAT 240
GGCAACGTGT TCAAGACGCA TTTGTTGGGG CGGCCGCTGA TACGCGTGAC CGGCGCGGAG 300
AACGTGCGCA AGATCCTCAT GGGCGAGCAC CACCTCGTGA GCACCGAGTG GCCTCGCAGC 360
ACCCGCATGT TGCTGGGCCC CAACACGGTG TCCAATTCCA TTGGCGACAT CCACCGCAAC 420
AAGCGCAAGG TCTTCTCCAA GATCTTCAGC CACGAGGCCC TGGAGAGTTA CCTGCCCAAG 480
ATCCAGCTGG TGATCCAGGA CACACTGCGC GCCTGGAGCA GCCACCCCGA GGCCATCAAC 540
GTGTACCAGG AGGCGCAGAA GCTGACCTTC CGCATGGCCA TCCGGGTGCT GCTGGGCTTC 600
AGCATCCCTG AGGAGGACCT TGGGCACCTC TTTGAGGTCT ACCAGCAGTT TGTGGACAAT 660
GTCTTCTCCC TGCCTGTCGA CCTGCCCTTC AGTGGCTACC GGCGGGGCAT TCAGGCTCGG 720
CAGATCCTGC AGAAGGGGCT GGAGAAGGCC ATCCGGGAGA AGCTGCAGTG CACACAGGGC 780
AAGGACTACT TGGACGCCCT GGACCTCCTC ATTGAGAGCA GCAAGGAGCA CGGGAAGGAG 840
ATGACCATGC AGGAGCTGAA GGACGGGACC CTGGAGCTGA TCTTTGCGGC CTATGCCACC 900
ACGGCCAGCG CCAGCACCTC ACTCATCATG CAGCTGCTGA AGCACCCCAC TGTGCTGGAG 960
AAGCTGCGGG ATGAGCTGCG GGCTCATGGC ATCCTGCACA GTGGCGGCTG CCCCTGCGAG 1020
GGCACACTGC GCCTGGACAC GCTCAGTGGG CTGCGCTACC TGGACTGCGT CATCAAGGAG 1080
GTCATGCGCC TGTTCACGCC CATTTCCGGC GGCTACCGCA CTGTGCTGCA GACCTTCGAG 1140
CTTGATGGTT TCCAGATCCC CAAAGGCTGG AGTGTCATGT ATAGCATCCG GGACACCCAT 1200
GACACAGCGC CCGTGTTCAA AGACGTGAAC GTGTTCGACC CCGATCGCTT CAGCCAGGCG 1260
CGGAGCGAGG ACAAGGATGG CCGCTTCCAT TACCTCCCGT TCGGTGGCGG TGTCCGGACC 1320
TGCCTGGGCA AGCACCTGGC CAAGCTGTTC CTGAAGGTGC TGGCGGTGGA GCTGGCTAGC 1380 ACCAGCCGCT TTGAGCTGGC TACACGGACC TTCCCCCGCA TCACCTTGGT CCCCGTCCTG 1440 CACCCCGTGG ATGGCCTCAG CGTCAAGTTC TTTGGCCTGG ACTCCAACCA GAACGAGATC 1500 CTGCCGGAGA CGGAGGCCAT GCTGAGCGCC ACAGTCTAAC CCAAGACCCA CCCGCCTCAG 1560 CCCAGCCCAG GCAGCGGGGT GGTGGTTGTG GGAGGTAGAA ACCTGTGTGT GGGAGGGGGC 1620 CGGAACGGGG AGGGCGAGTG GCCCCCATAC TTGCCCTCCC TTGCTCCCCC TCCCTGGCAA 1680 ACCCTACCCA AAGCCAGTGG GCCCCATTCC TAGGGCTGGG CTCCCCTTCT GGCTCCAGCT 1740 TCCCTCCAGC CACTCCCCAT TTACCATCAG CTCAGCCCCT GGGAAGGGCG TGGCAGGGGC 1800 TCTGCATGCC CGTGACAGTG TTAGGTGTCA GCGCGTGCTA CAGTGTTTTT GTGATGTTCT 1860 GAACTGCTCC CTTCCCTCCG TTCCTTTCGG ACCCTTTTAG CTGGGGTTGG GGGACGGGAA 1920 GAGCCGTGCC CCCTTGGGCG CACTCTTCAG CGTCTCCTCC TCCTGCGCCC CCACTGCGTC 1980 TGCCCAGGAA CAGCATCCTG GGTAGCAGAA CAGGAGTCAA CCTTGGCGGG GCGGGGGCTG 2040 CGTCCAACCT GGAGATTGCC CTTCCCTATG CCACGGTTCC CACCCTCCCT CACCAGTTTG 2100 GACAATTTGA AATTACCTAT TGCTGCTACT TGTTCTGTCC TCTGACCTTG GGGCAAAGGA 2160 GCCCCAGGCC CTGTCTCCCC AGCATCCTCC CTGGTGGCCC TGGGCAGGTG CACTGACACC 2220 CCCACCTTCC CATCCCCTGC TGAACCAGGC CCTGTTACAC ACAGCCGCCT AAGGCCCGCG 2280 GCTCATGTGC TGCCCGCCCC CATATTTATT CACTGATAGA GAATCTTGGG GATGCTGGGG 2340 TCTGGAGTGA ACATCTCCTC CCCTTCATGC CCTAGCCTGT GTTCTAGCTG TCCTGGCGAG 2400 ACTTCTGTGA GTGAAGAGGA AGGGGTCTCT GGTCAAACCC AGCCCCCAGG GCCTAGGGTT 2460 GAAAGCCTTC CCCGGCTCCG GGCATTATTT GGGTTTAATC TCGGAGCCTC ACTCCTGGAC 2520 TGAAGTCCGG TGCCTCTGCC TTATCCCTGG TGGAGATGGA ATGTGGCCCA TTGCCTCCTC 2580 CCTCTCCTGT CAAAAACCCT GATCAGGTAG ATTTGGAGGC GGCCACGATT TCCTGTTTGG 2640 CCCCTGTTCA CCCCAGTGCA CTGGCCCTGA CTCCAGGCGT GAGTATGGGG AAGGATACGG 2700 GTTCTTCTGA CGGGGAGCAA GGGCCTCCGT CTTCCCTTCC TTAACTCTCC CCCTTTGCCC 2760 TCCGCCCTGA AAAAGGTGTC CTTGAAGTCC CTTCCACCTC TATGCCACTG TCTGCTTAGC 2820 CCAGCTCAGG GGTGGGGAAG AGGCGAAAGC GTGGGGGAGG TGAGCGCAGC GGCAGTTCTG 2880 CCTCGGAGCT GATTGCAGGG CCCTGTGTGG TCTCCGGACA GCTGCGGGAA GGCTGCCGCA 2940 GCTGAAGCTG AAGAGGCGGC TACGTGCGGT TTGTCAGGGG GATTGGGTTG AAAACTGGCC 3000 AGTCGGGATG ACTGGGTGAA AGAGGAGTAG CTCCTGCCAC TGGCGTTTTG AGTGTTGGCA 3060 ATTTGGGATG CCTCCTGGGG AAGGTTTCCG GGCGTTTGGT GAGTCTCTAG ATTTTTCCTT 3120 GCTTTCTGTG TTTATTGGTT TTTGATGTTG TAAAAGCAAT GAATCCCCTT TACAAGAAAA 3180 TCGAAAACAC AGAAGAATGA AGGACATGCC AGTCCCCGAT CGCTGCTGTG AGCACCTCAG 3240 TGGCTCCCTC AGACCAGATC CCGTAGGCAG CCCCACAGAC CGACCCTGAC CCCACTCACA 3300 GCCACCCTGA AGATAGACTA TAGGAACGGG CCCATACCAC ACAGACTGCT CTCCAATCCC 3360 TGAGTCTCAG ATGTTTCATT TATTTCCTAC TTTTCCACTA CTAAAAAACA GTGTGGAATA 3420 GACATTATTG GCAAAATTGC TCATCCCTAA TCCTGAAAAA CAGGCCAGAA TGGGTAAAGA 3480 CTTGTCAAAG CTTGCAACAT AGCTACATGG TGCACCCGGA CCTGTACCCC CTCCCCCCAA 3540 CACAAAACCA GTGTCTGGGA GGTTCATTTT CCTTTAAACT GATCCAGCTG GCCCTGAACC 3600 AATTGTTTTT GACTGAGTAT CTAGGAGAGC AGTAAGTGGA ACTTCAGACA AGCCCACTGG 3660 GTCTGGTCCA GGTGAGGGGC AGGGGGCATG GGGCTGGGAG GTCTCAGGGG CCTTCCCTGG 3720 GGGTGGCCAG CCTGGTAGGG GGCAGAGAAG GAAAAGCTGA GGGGGGTCCC TGTGAGGGAG 3780 GAAAGAAGGA TCATTTGCCC CGCTGGGTCT CAAAGGCAGT GAGAAGAGAG CTGAAGAAAG 3840 CTCTGGCTGG CTGACAGGAT CCCTGTGTTG TAATTGGTCC CTCCTTTCAG CTCTCTAGTG 3900 AGATGCCCGT GTCTGTGCGT GTGCGTGTGT GTTTCATACA GCTAGCATTA GATGGGTGAT 3960 GTTTCTTACT TATCATCCCT AACTATTGCA ACTTGACCTT AAAAAGACAA AACCCCACAA 4020 AACTCTTCCT GCCACGGGCT TGCAGATTGA AGCACTTTCG ATGTTGGGCG CTGGCGTTTG 4080 TGTTCTGGGC ACCACCGTGA CCCTGCCCAG ATGGCTATAA TATTATTTTA TACACAAACC 4140 TTTTTTTTCA TAAATGTTAT AATTTTGTGT CTGTCTTTAT AAACTATTAT AAGTACTATT 4200 TTTGTTATAA TTCAAAATAG ATATTTAGTA TAAAGTTTTT GCTGTTAAAT ATTTGTTATT 4260 TAGTAAAATA TGAATTTTGC TCTATTGTAA ACATGGTTCA AAATATTAAT ATGTTTTTAT 4320 CACAGTCGTT TTAATATTGA . AAAAGCACTT GTGTGTTTTG TTTTGATATG AAACTGGTAC 4380 CGTGTGAGTG TTTTTGCTGT CGTGGTTTTA ATCTGTATAT AATATTCCAT GTTGCATATT 4440 AAAAA
Seq ID NO: B47 Protein sequence Protein Accession #: NP 063938.1
60
120
Figure imgf000816_0001
180
VYQEAQKLTF RMAIRVLLGF SIPEEDLGHL FEVYQQFVDN VFSLPVDLPF SGYRRGIQAR 240
QILQKGLEKA IREKLQCTQG KDYLDALDLL IESSKEHGKE MTMQELKDGT LELIFAAYAT 300
TASASTSLIM QLLKHPTVLE KLRDELRAHG ILHSGGCPCE GTLRLDTLSG LRYLDCVIKE 360
VMRLFTPISG GYRTVLQTFE LDGFQIPKGW SVMYSIRDTH DTAPVFKDVN VFDPDRFSQA 420
RSEDKDGRFH YLPFGGGVRT CLGKHLAKLF LKVLAVELAS TSRFELATRT FPRITLVPVL 480
HPVDGLSVKF FGLDSNQNEI LPETEAMLSA TV
Seq ID NO: B48 DNA sequence Nucleic Acid Accession #: AB040527.1; AL136582.1 Coding sequence: 94..2319
11 21 31 41 51
I I I I I
GCGGCTGCGG GGTTCCTGGT GCTGAGGACG GACGCCATTG GAGTTCCCGA GAAGCATGGC 60 TGAGGGAAGC TTCAGCGTGC AATCGGAAAG CTACAGTGTT GAAGACATGG ATGAGGGTAG 120 CGACGAAGTC GGGGAGGAAG AGATGGTTGA AGGCAACGAC TATGAAGAAT TCGGTGCGTT 180 TGGTGGCTAT GGCACCCTCA CCAGCTTTGA CATCCATATC CTCAGAGCCT TCGGAAGCTT 240 GGGTCCAGGC CTTCGCATCT TATCGAATGA GCCCTGGGAA CTGGAAAACC CTGTGCTGGC 300 CCAGACCCTG GTGGAGGCAT TGCAGCTGGA TCCGGAAACA CTTGCCAATG AGACGGCCGC 360 CCGTGCTGCC AACGTAGCCC GCGCCGCCGC CTCCAACCGT GCGGCTCGGG CCGCTGCCGC 420 CGCTGCCCGT ACCGCCTTCA GTCAGGTGGT CGCTAGCCAC CGGGTGGCCA CGCCGCAGGT 480 CTCAGGAGAG GATACCCAGC CCACGACCTA CGCCGCCGAG GCTCAGGGGC CCACCCCTGA 540 GCCACCCCTT GCTTCTCCGC AGACCTCCCA GATGTTAGTC ACCAGTAAGA TGGCTGCCCC 600 CGAGGCTCCG GCAACCTCCG CACAGTCCCA GACAGGCTCC CCGGCCCAGG AGGCTGCTAC 660 TGAGGGCCCT AGTAGCGCCT GTGCTTTCTC TCAGGCTCCG TGTGCCAGGG AGGTGGACGC 720 CAACCGGCCC AGCACAGCCT TCCTGGGCCA GAATGATGTC TTCGATTTCA CTCAGCCGGC 780 AGGTGTCAGT GGCATGGCCT TCCCGCGCCC CAAGAGACCT GCCCCAGCCC AAGAGGCTGC 840 CACAGAGGGC CCCAGTGCTG CCTCTGGTGT GCCCCAGACG GGACCTGGCA GGGAGGTGGC 900 AGCCACCCGG CCCAAGACCA CCAAGTCGGG GAAGGCGCTG GCCAAGACTC GGTGGGTGGA 960 GCCTCAGAAT GTTGTGGCAG CAGCTGCTGC CAAGGCCAAG ATGGCCACGA GCATCCCTGA 1020 GCCGGAGGGT GCAGCTGCTG CCACTGCTCA GCACAGTGCT GAGCCCTGGG CCAGGATGGG 1080 AGGCAAGAGG ACCAAGAAGT CCAAGCACCT GGATGATGAG TATGAGAGCA GCGAGGAGGA 1140 GAGAGAGACT CCCGCGGTCC CACCCACCTG GAGAGCATCA CAGCCCTCAT TGACGGTGCG 1200 GGCTCAGTTG GCCCCTCGGC CCCCGATGGC CCCGAGGTCC CAGATACCCT CAAGGCACGT 1260 ACTGTGCCTG CCCCCCCGCA ACGTGACCCT TCTGCAGGAG AGGGCAAATA AGTTGGTGAA 1320 ATACCTGATG ATTAAGGACT ACAAGAAGAT CCCCATCAAG CGCGCAGACA TGCTGAAGGA 1380 TGTCATCAGA GAATATGATG AACATTTCCC TGAGATCATT GAACGAGCAA CGTACACCCT 1440 GGAAAAGAAG TTTGGGATCC ACCTGAAGGA GATCGACAAG GAAGAACACC TGTATATTCT 1500 TGTCTGCACA CGGGACTCCT CAGCTCGCCT CCTTGGAAAA ACCAAGGACA CTCCCAGGCT 1560 GAGTCTCCTC TTGGTGATTC TGGGCGTCAT CTTCATGAAT GGCAACCGTG CCAGCGAGGC 1620 TGTCCTCTGG GAGGCACTAC GCAAGATGGG ACTGCGCCCT GGGGTGAGGC ACCCATTCCT 1680 CGGCGATCTG AGGAAGCTCA TCACAGATGA CTTTGTGAAG CAGAAGTACC TGGAATACAA 1740 GAAGATCCCC AACAGCAACC CACCTGAGTA TGAATTCCTC TGGGGCCTGC GAGCCCGCCA 1800 TGAGACCAGC AAGATGAGGG TCCTGAGATT CATCGCCCAG AATCAGAACC GAGACCCCCG 1860 GGAATGGAAG GCTCATTTCT TGGAGGCTGT GGATGATGCT TTCAAGACAA TGGATGTGGA 1920 TATGGCCGAG GAACATGCCA GGGCCCAGAT GAGGGCCCAG ATGAATATCG GGGATGAAGC 1980 GCTGATTGGA CGGTGGAGCT GGGATGACAT ACAAGTCGAG CTCCTGACCT GGGATGAGGA 2040 CGGAGATTTT GGCGATGCCT GGGCCAGGAT CCCCTTTGCT TTCTGGGCCA GATACCATCA 2100 GTACATTCTG AATAGCAACC GTGCCAACAG GAGGGCCACG TGGAGAGCTG GCGTCAGCAG 2160 TGGCACCAAT GGAGGGGCCA GCACCAGCGT CCTAGATGGC CCCAGCACCA GCTCCACCAT 2220 CCGGACCAGA AATGCTGCCA GAGCTGGCGC CAGCTTCTTC TCCTGGATCC AGCACCGTTG 2280 ACGAACTGCA GCGATCTTAC TGGCCAAGCC AGAGCGCCTC CTCTCAGATT CCTTCTCGAC 2340 ACAGCACCCT AGGCGGCTTC TTCCTGTCAG TCGGAGGTGG CATGCAAGAT GAAGCTCTCT 2400 TTGCTCTTCC TGCTTTCATT TTGTGCTTTT CCTTGTGTTT TCATGTTTTG GGTATCAGTG 2460 TTACATTAAA GTTGCAAAAT TAAA
Seq ID NO: B49 Protein sequence
Protein Accession # : BAB33378.1 ; CAB66517.1
1 11 21 31 41 51
I I I I I
M 1AEGSFSVQS ESYSVEDMDE GSDEVGEEEM VEGNDYEEFG AFGGYGTLTS FDIHILRAFG 60 SLGPGLRILS NEPWELENPV LAQTLVEALQ LDPETLANET AARAANVARA AASNRAARAA 120 AAAARTAFSQ WASHRVATP QVSGEDTQPT TYAAEAQGPT PEPPLASPQT SQMLVTSKMA 180 APEAPATSAQ SQTGSPAQEA ATEGPSSACA FSQAPCAREV DANRPSTAFL GQNDVFDFTQ 240 PAGVSGMAFP RPKRPAPAQE AATEGPSAAS GVPQTGPGRE VAATRPKTTK SGKALAKTRW 300 VEPQNWAAA AAKAKMATSI PEPEGAAAAT AQHSAEPWAR MGGKRTKKSK HLDDEYESSE 360 EERETPAVPP TWRASQPSLT VRAQLAPRPP MAPRSQIPSR HVLCLPPRNV TLLQERANKL 420 VKYLMIKDYK KIPIKRADML KDVIREYDEH FPEIIERATY TLEKKFGIHL KEIDKEEHLY 480 ILVCTRDSSA RLLGKTKDTP RLSLLLVILG VIFMNGNRAS EAVLWEALRK MGLRPGVRHP 540 FLGDLRKLIT DDFVKQKYLE YKKIPNSNPP EYEFLWGLRA RHETSKMRVL RFIAQNQNRD 600 PREWKAHFLE AVDDAFKTMD VDMAEEHARA QMRAQMNIGD EALIGRWSWD DIQVELLTWD 660 EDGDFGDAWA RIPFAFWARY HQYI NSNRA NRRATWRAGV SSGTNGGAST SVLDGPSTSS 720 TIRTRNAARA GASFFSWIQH R
Seq ID NO: B50 DNA sequence
Nucleic Acid Accession #: XM_084965.1
Coding sequence: 356..2014
11 21 31 41 51
I I I I I
GACCTAGCGT GTGCTCAGCT CTGGACAAGA CATGGATGTA GGCAGACATG CTTCCTGCCT 60 GCTGGGCTTA GTGCACCAAT GCTAAGGACA GACATGAAGG GCTTGGGAAA GGCATGAAGA 120 TGCAGGGAGT CTAGGAGAGA GGATAAGAAA AACAAGCATT TTGTGGTGGG TTGAATTGCG 180 TTGTCGTTTT TAGAGGCATT TCGTGATCCA TGGTTGCGCT CCCGTGAAGA GCGAGTCTAG 240 AGAAGGAATC CGAAGCGGCG GCGGCGAGCG CGGCTCAGGT TGATTTAGAA TACGGGTGAC 300 AGTGGCCTGG CGCGAGCCCA CTGCTGACGA AAGCGGCTTA TCCCGCGCGG TTTCCATGGA 360 GACGAGCCGG AGCCGCGGCG GCGGCGGGGC TGTCAGCGAG CGCGGCGGAG CTGGCGCGTC 420 CGTGGGGGTC TGCAGGAGGA AGGCGGAGGC CGGGGCCGGG ACCGGGACCC TCGCGGCAGA 480 CATGGACTTG CATTGTGACT GTGCCGCCGA AACGCCGGCC GCCGAGCCGC CGTCGGGGAA 540 GATTAATAAA GCTGCCTTCA AATTATTCAA GAAGAGGAAA TCGGGTGGCA CCATGCCCAG 600 CATTTTTGGG GTCAAAAACA AAGGGGACGG GAAAAGCTCG GGTCCGACGG GGCTGGTGAG 660 GAGCAGGACC CACGACGGAC TTGCCGAGGT GCTGGTGCTG GAGAGCGGCA GGAAGGAGGA 720 GCCGCGCGGC GGGGGCGACA GCGGCGGGGG CGGCGGGGGG CGGCCGAACC CGGGGCCCCC 780 CAGAGCCGCA GGGCCCGGCG GGGGCTCCCT CGCCAGCAGC TCGGTGGCCA AGTCGCACAG 840 CTTCTTCTCG CTGCTGAAGA AGAACGGGCG CTCGGAAAAC GGCAAGGGAG AGCCTGTGGA 900 CGCGAGCAAG GCCGGCGGCA AACAAAAGCG GGGGCTGCGG GGGCTGTTCA GCGGCATGCG 960 CTGGCACAGG AAAGACAAGC GGGCCAAGGC GGAGGCCGCG GAGGGGCGCG CGCCCGGGGG 1020 CGGCTTGATC CTACCCGGCT CGCTCACCGC CAGCCTGGAG TGCGTCAAGG AGGAGACGCC 1080 CAGAGCCGCG CGCGAGCCGG AGGAGCCCAG CCAGGACGCC CCGCGAGACC CAGCAGGCTG 1140 TGGAGATATT ATTGCAGACC AAGAGGAAGA GGCAGGTCCC AGCTGTGACA AGCATGTCCC 1200 CGGGCCAGGC AAGCCGGCTC TGTCTAAAAA GAACCCCGGC GTGGTGGCCT ACCAAGGAGG 1260 CGGGGAAGAG ATGGCCAGCC CGGACGAGGT GGACGACACC TATCTACAGG AGTTCTGGGA 1320 CATGCTCTCC CAGACCGAGG AGCAGGGACC CGAGCCCCAG GAGGGCGCGG CTAAGGTGGC 1380 AGCTGCGCTG GAAACCAAGG TGGTGCCCGA GACCCCCAAA GACACCAGGT GTGTGGAAGC 1440 GGCCAAGGAC GCGTCCTCGG TCAAGCGCAG GAGGCTCAAC CGGATTCCCA TCGAGCCCCA 1500 TCCTAAGGAG GAGCCCAAGC ACCCGGAGAA GGAGCAGCAG GAAGGCGTCC CCAACAGCGA 1560 CGAGGGCTAC TGGGACTCCA CCACGCCAGG CCCAGAGGAA GACAGCTCGA GCAGCGGGAA 1620 GAAGGCGGGC ATCCCCCGGG ATAGCTACAG CGGGGACGCG CTCTATGATC TCTATGCTGA 1680 CCCGGACGGA AGTCCAGCAA CCCTTCCTGG AGGGAAGGAC AACGAGGAGA CGTCCTCCCT 1740 GTCCCGGTTA AAGCCCGTAT CTCCAGGCAC CATCACCTGT CCACTGCGAA CACCAGGCAG 1800 CTTGCTGAAG GACTCTAAGA TCCCTATTAG CATCAAGCAC CTGACCAACC TTCCATCTAG 1860 CCATCCCGTG GTGCACCAGC AACCCTCCAG GAGTGAGATG CCCAGAACAA AAATCCCGGT 1920 TTCCAAAGTG CTGGTCCGCA GAGTCAGCAA CCGGGGCTTG GCTGGGACCA CCATCAGAGC 1980 AACGGCCTGC CACGACAGTG CCAAAAAGTT GTGAGGTCTT CCAGGCCAAG GTGGATGGGC 2040 CCCATGCCAA GGAATACAAC TTTTCCCTGG AAACCACTAA AGTAAGTTTT GCTTTTCCTA 2100 AAGAAAGTCT TTTAGGACAC CACCCGTCCC CCGCCCTGCT CCAGAGCGTG GACCGAGGAG 2160 GTCTTTGTGC CCTGAGCAGG GACCGGATAA CACCAGAAAG .AGGGATGCTA CACGGGGGTT 2220 TCTCCTCTCA AGATAAGTCC CTGAGAATTA TTTTCAAGCA CTTTTTTCTT TTTTACCTTT 2280 AAGTTTTTCT TCCTTTTGCT TTAATATACT GAACACTTGG AAGTCACCTT TACTTGCCTT 2340 TGCAGAAAAC AGAACTTAGC CAAACCTAAG TAAGAGTCAT GCCTGGATAT TGGGATAAGC 2400 CAGTGTCTAG AGGCCTGAAG GAACCGCTGA AGAACCAGAG GAGATCTCCT CTTCCAAGAC 2460 ACGTTTCCTT CCTTCCCTTC TTTCCTCTTT CCTTTCCAGT T
Seq ID NO: B51 Protein sequence Protein Accession #: XP 084965.1
1 11 21 31 41 51 1 1 1| | 1 1| 1| 1I METSRSRGGG GAVSERGGAG ASVGVCRRKA EAGAGTGTLA ADMDLHCDCA AETPAAEPPS 60
GKINKAAFKL FKKRKSGGTM PSIFGVKNKG DGKSSGPTGL VRSRTHDGLA EVLVLESGRK 120
EEPRGGGDSG GGGGGRPNPG PPRAAGPGGG SLASSSVAKS HSFFSLLKKN GRSENGKGEP 180
VDASKAGGKQ KRGLRGLFSG MRWHRKDKRA KAEAAEGRAP GGGLILPGSL TASLECVKEE 240
TPRAAREPEE PSQDAPRDPA GCGDIIADQE EEAGPSCDKH VPGPGKPALS KKNPGWAYQ 300
GGGEEMASPD EVDDTYLQEF WDMLSQTEEQ GPEPQEGAAK VAAALETKW PETPKDTRCV 360
EAAKDASSVK RRRLNRIPIE PHPKEEPKHP EKEQQEGVPN SDEGYWDSTT PGPEEDSSSS 420
GKKAGIPRDS YSGDALYDLY ADPDGSPATL PGGKDNEETS SLSRLKPVSP GTITCPLRTP 480
GSLLKDSKIP ISIKHLTNLP SΞHPWHQQP SRSEMPRTKI PVSKVLVRRV SNRGLAGTTI 540
RATACHDSAK KL
Seq ID NO: B52 DNA sequence Nucleic Acid Accession #: FGENESH predicted Coding sequence: 1..2016
11 21 31 41 51
I I I
ATGGAGACGA G 1CCGGAGCCG CGGCGGCGGC GGGGCTGTCA GCGAGCGCGG CGGAGCTGGC 60 GCGTCCGTGG GGGTCTGCAG GAGGAAGGCG GAGGCCGGGG CCGGGACCGG GACCCTCGCG 120 GCAGACATGG ACTTGCATTG TGACTGTGCC GCCGAAACGC CGGCCGCCGA GCCGCCGTCG 180 GGGAAGATTA ATAAAGCTGC CTTCAAATTA TTCAAGAAGA GGAAATCGGG TGGCACCATG 240 CCCAGCATTT TTGGGGTCAA AAACAAAGGG GACGGGAAAA GCTCGGGTCC GACGGGGCTG 300 GTGAGGAGCA GGACCCACGA CGGACTTGCC GAGGTGCTGG TGCTGGAGAG CGGCAGGAAG 360 GAGGAGCCGC GCGGCGGGGG CGACAGCGGC GGGGGCGGCG GGGGGCGGCC GAACCCGGGG 420 CCCCCCAGAG CCGCAGGGCC CGGCGGGGGC TCCCTCGCCA GCAGCTCGGT GGCCAAGTCG 480 CACAGCTTCT TCTCGCTGCT GAAGAAGAAC GGGCGCTCGG AAAACGGCAA GGGAGAGCCT 540 GTGGACGCGA GCAAGGCCGG CGGCAAACAA AAGCGGGGGC TGCGGGGGCT GTTCAGCGGC 600 ATGCGCTGGC ACAGGAAAGA CAAGCGGGCC AAGGCGGAGG CCGCGGAGGG GCGCGCGCCC 660 GGGGGCGGCT TGATCCTACC CGGCTCGCTC ACCGCCAGCC TGGAGTGCGT CAAGGAGGAG 720 ACGCCCAGAG CCGCGCGCGA GCCGGAGGAG CCCAGCCAGG ACGCCCCGCG AGACCCAGCA 780 GGTGAGCCCG CAGGGGGAGA GGAGGTGCCC GCCCCCGCCG ACCGCGCCCC AGCGCGGAGC 840 TGCCGAGAGG CAGAGGGCCT CGCGCACCCC GGCGACACCβ GCGCCCGGGG AGAGGACGCC 900 GCGGGGCATC GGCGCGCCGA GCCGGGGCCC GGGGAGGTCC GCACGGCAGA GGACGCTTCC 960 AGGACGGGGG CCGTTCCCGT AAAGACGGTC CCCCTTGTCG ACTCCGAAGG CGGCAGCGGC 1020 CGGGCGCCCG CCGCCCCAGA CCCTGCCTCT GTCGATCCAC CCTCAGACCC GTCGGCAGAT 1080 CGTATTTGTT TGATGTTTTC TGACGTGACT TCACTGAAAA GCTTTGACTC TCTTACAGGC 1140 TGTGGAGATA TTATTGCAGA CCAAGAGGAA GAGGCAGGTC CCAGCTGTGA CAAGCATGTC 1200 CCCGGGCCAG GCAAGCCGGC TCTGTCTAAA AAGAACCCCG GCGTGGTGGC CTACCAAGGA 1260 GGCGGGGAAG AGATGGCCAG CCCGGACGAG GTGGACGACA CCTATCTACA GGAGTTCTGG 1320 GACATGCTCT CCCAGACCGA GGAGCAGGGA CCCGAGCCCC AGGAGGGCGC GGCTAAGGTG 1380 GCAGCTGCGC TGGAAACCAA GGTGGTGCCC GAGACCCCGA AAGACACCAG GTGTGTGGAA 1440 GCGGCCAAGG ACGCGTCCTC GGTCAAGCGC AGGAGGCTCA ACCGGATTCC CATCGAGCCC 1500 CATCCTAAGG AGGAGCCCAA GCACCCGGAG AAGGAGCAGC AGGAAGGCGT CCCCAACAGC 1560 GACGAGGGCT ACTGGGACTC CACCACGCCA GGCCCAGAGG AAGACAGCTC GAGCAGCGGG 1620 AAGAAGGCGG GCATCCCCCG GGATAGCTAC AGCGGGGACG CGCTCTATGA TCTCTATGCT 1680 GACCCGGACG GAAGTCCAGC AACCCTTCCT GGAGGGAAGG ACAACGAGGA GACGTCCTCC 1740 CTGTCCCGGT TAAAGCCCGT ATCTCCAGGC ACCATCACCT GTCCACTGCβ AACACCAGGC 1800 AGCTTGCTGA AGGACTCTAA GATCCCTATT AGCATCAAGC ACCTGACCAA CCTTCCATCT 1860 AGCCATCCCG TGGTGCACCA GCAACCCTCC AGGAGTGAGA TGCCCAGAAC AAAAATCCCG 1920 GTTTCCAAAG TGCTGGTCCG CAGAGTCAGC AACCGGGGCT TGGCTGGGAC CACCATCAGA 1980 GCAACGGCCT GCCACGACAG TGCCAAAAAG TTGTGA
Seq ID NO: B53 Protein sequence Protein Accession ft: FGENESH predicted
1 11 21 31 41 51
I I I I I
METSRSRGGG G 1AVSERGGAG ASVGVCRRKA EAGAGTGTLA ADMDLHCDCA AETPAAEPPS 60 GKINKAAFKL FKKRKSGGTM PSIFGVKNKG DGKSSGPTGL VRSRTHDGLA EVLVLESGRK 120 EEPRGGGDSG GGGGGRPNPG PPRAAGPGGG SLASSSVAKS HSFFSLLKKN GRSENGKGEP 180 VDASKAGGKQ KRGLRGLFSG MRWHRKDKRA KAEAAEGRAP GGGLILPGSL TASLECVKEE 240 TPRAAREPEE PSQDAPRDPA GEPAGGEEVP APADRAPARS CREAEGLAHP GDTGARGEDA 300 AGHRRAEPGP GEVRTAEDAS RTGAVPVKTV PLVDSEGGSG RAPAAPDPAS VDPPSDPSAD 360 RICLMFSDVT SLKSFDSLTG CGDIIADQEE EAGPSCDKHV PGPGKPALSK KNPGWAYQG 420 GGEEMASPDE VDDTYLQEFW DMLSQTEEQG PEPQEGAAKV AAALETKWP ETPKDTRCVE 480 AAKDASSVKR RRLNRIPIEP HPKEEPKHPE KEQQEGVPNS DEGYWDSTTP GPEEDSSSSβ 540 KKAGIPRDSY SGDALYDLYA DPDGSPATLP GGKDNEETSS LSRLKPVSPG TITCPLRTPG 600 SLLKDSKIPI SIKHLTNLPS SHPWHQQPS RSEMPRTKIP VSKVLVRRVS NRGLAGTTIR 660 ATACHDSAKK L
Seq ID NO: B54 DNA sequence 0 Nucleic Acid Accession #: NM_014138.1
Coding sequence: 60..854
1 11 21 31 41 51 1 5 1 | 1 | 1 1 I 1 | 1
CTGCAGAGAC TTCCCAGGAA GGTCCAGCGC CCTCTCAGCC TTCGTACTCA GAACAGCCGA 60
TGATGGGCCT CAGTAACCTG AGCCCCGGTC CTGGCCCCAG CCAGGCCGTG CCTCTCCCAG 120
AGGGGCTGCT CCGCCAGCGG TACAGAGAGG AGAAGACCCT GGAAGAGCGG CGGTGGGAGA 180
GGCTGGAGTT CCTTCAGAGG AAGAAAGCAT TCCTGCGGCA TGTGAGGAGG AGACACCGCG 240
ATCACATGGC CCCCTATGCT GTTGGGAGGG AAGCCAGAAT CTCCCCATTA GGTGACAGAA 300 0 GTCAGAATCG ATTCCGATGT GAATGTCGAT ACTGCCAGAG CCACAGGCCG AATCTTTCTG 360
GGATCCCTGG GGAGAGTAAC AGGGCCCCAC ATCCCTCCTC CTGGGAGACG CTGGTGCAGG 420
GCCTCAGTGG CTTGACTCTC AGCCTAGGCA CCAACCAGCC CGGGCCTCTG CCTGAAGCGG 480
CACTCCAGCC ACAGGAGACA GAGGAGAAGC GCCAGCGAGA GAGGCAGCAG GAGAGCAAAA 540
TAATGTTTCA GAGGCTGCTC AAGCAGTGGT TAGAGGAAAA CTGAGACGTG CACCCCCATG 600 5 GGATGGAGAC CCGAAGGGAC TCAGACGGAG CCGCCGTGTT GGCAGCGCCT GGGTGTGGGC 660
CCATTTTGGG GACCAAACAG CAAGCTGTGG TCGGATGAGT GCCAGGACCT GTGTACCGGG 720
ACACGTGGGA GTCCTCCCAG CATGATGCTT GACTGACCCG AGGAAGGTCC TCATGTTTCG 780
TGCCTGTCAT TCTCGGATGG CTGTGAGGCA TTCCTTGGCA AGGGACGCTG CGTACCAGCG 840
GTCCTCACCG CATCTCACAT GGCTCCTGTG ATGCATGTTG TCGCTTTCCC ACCCGGGATC 900
30 TCCATCTCTC TTCCCTTCCT GCTGTCAGTA AGAGATCACA TGTCTGTGTA GTGTGAATGC 960
CTTGTCGCTG TCCTGTGCTT TTGCACCATT GAGTTGACTG CCTCTGAGAA GCAGCACTAG 1020
GCCTGTTGAA ATGCAATGTG CTGCCCTGAG ATCCAGTTTC AAGAATGGGC AGGTAAACGC 1080
AGTGTGGGAA AGGAATGTGG AATGAGAACT TGGTGGTTCA CCGCTGTACT ATTTGTGTAA 1140
ATGTTTACGT ATGTGATAAG CTACATGTAT GTAAATGTTG CAATACCCCT AACAGTCGAG 1200
35 TAGTAGTCTC CCTTACAGGA ATTTTTGACG GGGTTCCTCA TCATCAATAC CAAATAAATA 1260
TATGTAGGAA TGGAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 1320
AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 1380
AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAA
40 Seq ID NO: B55 Protein sequence Protein Accession #: NP 054857.1
1 11 21 31 41 51
__> M'MGLSNLSPG P'GPSQAVPLP E'GLLRQRYRE E'KTLEERRWE R'LEFLQRKKA F•LRHVRRRHR 60 DHMAPYAVGR EARISPLGDR SQNRFRCECR YCQSHRPNLS GIPGESNRAP HPSSWETLVQ 120 GLSGLTLSLG TNQPGPLPEA ALQPQETEEK RQRERQQESK IMFQRLLKQW LEEN
Seq ID NO: B56 DNA sequence 50 Nucleic Acid Accession #: NM_000025.1 Coding sequence: 198..1424
11 21 31
55 σcTACTccTC CCCCAAGAGC GGTGGCACCG AGGGAGTTGG GGTGGGGGGA GGCTGAGCGC 60
TCTGGCTGGG ACAGCTAGAG AAGATGGCCC AGGCTGGGGA AGTCGCTCTC ATGCCTTGCT 120
GTCCCCTCCC CTGAGCCAGG TGATTTGGGA GACCCCCTCC TTCCTTCTTT CCCTACCGCC 180
CCACGCGCGA CCCGGGGATG GCTCCGTGGC CTCACGAGAA CAGCTCTCTT GCCCCATGGC 240
CGGACCTCCC CACCCTGGCG CCCAATACCG CCAACACCAG TGGGCTGCCA GGGGTTCCGT 300
60 GGGAGGCGGC CCTAGCCGGG GCCCTGCTGG CGCTGGCGGT GCTGGCCACC GTGGGAGGCA 360
ACCTGCTGGT CATCGTGGCC ATCGCCTGGA CTCCGAGACT CCAGACCATG ACCAACGTGT 420
TCGTGACTTC GCTGGCCGCA GCCGACCTGG TGATGGGACT CCTGGTGGTG CCGCCGGCGG 480
CCACCTTGGC GCTGACTGGC CACTGGCCGT TGGGCGCCAC TGGCTGCGAG CTGTGGACCT 540
CGGTGGACGT GCTGTGTGTG ACCGCCAGCA TCGAAACCCT GTGCGCCCTG GCCGTGGACC 600
65 GCTACCTGGC TGTGACCAAC CCGCTGCGTT ACGGCGCACT GGTCACCAAG CGCTGCGCCC 660
GGACAGCTGT GGTCCTGGTG TGGGTCGTGT CGGCCGCGGT GTCGTTTGCG CCCATCATGA 720
GCCAGTGGTG GCGCGTAGGG GCCGACGCCG AGGCGCAGCG CTGCCACTCC AACCCGCGCT 780
GCTGTGCCTT CGCCTCCAAC ATGCCCTACG TGCTGCTGTC CTCCTCCGTC TCCTTCTACC 840
TTCCTCTTCT CGTGATGCTC TTCGTCTACG CGCGGGTTTT CGTGGTGGCT ACGCGCCAGC 900
70 TGCGCTTGCT GCGCGGGGAG CTGGGCCGCT TTCCGCCCGA GGAGTCTCCG CCGGCGCCGT 960
CGCGCTCTCT GGCCCCGGCC CCGGTGGGGA CGTGCGCTCC GCCCGAAGGG GTGCCCGCCT 1020
GCGGCCGGCG GCCCGCGCGC CTCCTGCCTC TCCGGGAACA CCGGGCCCTG TGCACCTTGG 1080
GTCTCATCAT GGGCACCTTC ACTCTCTGCT GGTTGCCCTT CTTTCTGGCC AACGTGCTGC 1140
GCGCCCTGGG GGGCCCCTCT CTAGTCCCGG GCCCGGCTTT CCTTGCCCTG AACTGGCTAG 1200
75 GTTATGCCAA TTCTGCCTTC AACCCGCTCA TCTACTGCCG CAGCCCGGAC TTTCGCAGCG 1260
CCTTCCGCCG TCTTCTGTGC CGCTGCGGCC GTCGCCTGCC TCCGGAGCCC TGCGCCGCCG 1320
CCCGCCCGGC CCTCTTCCCC TCGGGCGTTC CTGCGGCCCG GAGCAGCCCA GCGCAGCCCA 1380
GGCTTTGCCA ACGGCTCGAC GGGGCTTCTT GGGGAGTTTC TTAGGCCTGA AGGACAAGAA 1440
GCAACAACTC TGTTGATCAG AACCTGTGGA AAACCTCTGG CCTCTGTTCA GAATGAGTCC 1500
80 CATGGGATTC CCCGGCTGTG ACACTCTACC CTCCAGAACC TGACGACTGG GCCATGTGAC 1560
CCAAGGAGGG ATCCTTACCA AGTGGGTTTT CACCATCCTC TTGCTCTCTG TCTGAGAGAT 1620
GTTTTCTAAA CCCCAGCCTT GAACTTCACT CCTCCCTCAG TGGTAGTGTC CAGGTGCCGT 1680
GGAGCAGCAG GCTGGCTTTG GTAGGGGCAC CCATCACCCG GCTTGCCTGT GCAGTCAGTG 1740
AGTGCTTAGG GCAAAGAGAG CTCCCCTGGT TCCATTCCTT CTGCCACCCA AACCCTGATG 1800 AGACCTTAGT GTTCTCCAGG CTCTGTGGCC CAGGCTGAGA GCAGCAGGGT AGAAAAGACC 1860
AAGATTTGGG GTTTTATCTC TGGTTCCCTT ATTACTGCTC TCAAGCAGTG GCCTCTCTCA 1920
CTTTAGCCAT GGAATGGCTC CGATCTACCT CACAGCAGTG TCAGAAGGAC TTCGCCAGGG 1980
TTTTGGGAGC TCCAGGGTTC ATAAGAAGGT GAACCATTAG AACAGATCCC TTCTTTTCCT 2040
TTTGCAATCA GATAAATAAA TATCACTGAA TGCAGTTCAT CCTCGGCCCA CTTTCCCTCC 2100
GTTTGTTTTC TTTTCATAAT CCACTTACTC CCTTCCCTTC TACTCTGCGC TGGCTTTTGA 2160
CAGAGGCAGT AAATTAGGCC TAATCCTCAC TCTTTTCTTC CTAATCTTCA TCAAACAAAA 2220
AATGAAAAGT CTGTCTGGAC GAAGGGGAGT GAGCTTGAGC CTTTGATATC TTGCTCCCCC 2280
ACCCTTCCTG AAACTCTTGA AATCCAGTTG CCATTGAGTA GCAAAGCCAC GCTCCCCACA 2340
GGACTTGGAC AGAGGGCCCA CAGGGGGATG GGCTGGCTGT GGCCAGGTTT AGGGCAGGGG 2400
GCATTTGTCC CCTCCATGCT ATAATCCAGT GGTGCCTTAC ATGGTGTGTG TGTGTGTGTG 2460
TGCGTGTGTG TGTGTGTGTG TGTGTCTGGA GGCACAGGCA CAAAGCATTG CTTGGGTTGG 2520
TCAAATGTCT TGTGTCATAA ATATATTCTG ATGTTTCCCA GCCTTTCCAC AACCTCTACC 2580
TTCCCACTCA CCTTCCCCAG CTACAAAAAT CTGTATTATC CTCTTAAAGT AAAACTGGAG 2640 TTAC
Seq ID NO: B57 Protein sequence Protein Accession #: NP_000016.1
1 11 21 31 41 51
I 1 I I I I
MAPWPHENΞS LAPWPDLPTL APNTANTSGL PGVPWEAALA GALLALAVLA TVGGNLLVIV 60
AIAWTPRLQT MTNVFVTSLA AADLVMGLLV VPPAATLALT GHWPLGATGC ELWTSVDVLC 120
VTASIETLCA LAVDRYLAVT NPLRYGALVT KRCARTAWL VWWSAAVSF APIMSQWWRV 180
GADAEAQRCH SNPRCCAFAS NMPYVLLSSS VSFYLPLLVM LFVYARVFW ATRQLRLLRG 240
ELGRFPPEES PPAPSRSLAP APVGTCAPPE GVPACGRRPA RLLPLREHRA LCTLGLIMGT 300
FTLCWLPFFL ANVLRALGGP SLVPGPAFLA LNWLGYANSA FNPLIYCRSP DFRSAFRRLL 360 CRCGRRLPPE PCAAARPALF PSGVPAARSS PAQPRLCQRL DGASWGVΞ
Seq ID NO: B58 DNA sequence
Nucleic Acid Accession #: NM__032553.1
Coding sequence: 37..1038
1 11 21 31 41 51 i i i I i i
CACCATTAGG CAAAGATAGT TTCTCTAGAG AGAATCATGC CTGCTAATTA CACGTGTACC 60
AGGCCAGATG GAGACAATAC AGATTTTCGA TACTTTATTT ATGCAGTGAC ATACACTGTC 120
ATTCTTGTGC CAGGTCTCAT AGGGAATATA TTAGCCCTGT GGGTATTCTA TGGTTATATG 180
AAAGAAACAA AACGAGCTGT GATATTTATG ATAAACTTAG CCATTGCTGA CTTACTACAA 240
GTTCTTTCCT TGCCACTGAG GATCTTCTAC TACTTGAATC ATGACTGGCC ATTTGGGCCT 300
GGTCTCTGCA TGTTCTGTTT CTACCTGAAG TATGTCAACA TGTATGCAAG CATCTACTTC 360
TTGGTCTGCA TCAGTGTGCG ACGATTTTGG TTTCTCATGT ACCCCTTTCG CTTCCATGAC 420
TGCAAACAGA AATATGACCT GTACATCAGC ATTGCTGGCT GGCTGATCAT CTGCCTTGCC 480
TGTGTACTCT TTCCACTCCT CAGAACCAGT GATGATACCT CTGGCAATAG GACCAAATGC 540
TTTGTGGATC TTCCTACCAG GAATGTCAAC CTGGCCCAGT CCGTTGTTAT GATGACCATT 600
GGCGAGTTGA TTGGGTTTGT AACTCCGCTT CTGATTGTCC TATATTGTAC CTGGAAGACG 660
GTTTTATCAC TGCAAGATAA ATATCCCATG GCCCAAGATC TTGGAGAGAA ACAGAAAGCC 720
TTGAAGATGA TTCTAACCTG TGCAGGGGTA TTCCTAATTT GCTTTGCACC TTATCATTTC 780
AGTTTTCCTT TAGATTTCCT GGTGAAGTCC AATGAAATTA AAAGCTGCCT AGCCAGAAGG 840
GTGATTCTAA TATTTCATTC TGTGGCATTG TGTCTTGCTA GTCTGAATTC ATGTCTTGAC 900
CCAGTCATAT ACTACTTTTC CACTAATGAG TTCCGAAGAC GGCTTTCAAG ACAAGATTTG 960
CATGACAGCA TCCAACTCCA TGCAAAATCC TTTGTGAGTA ACCATACAGC TTCCACCATG 1020
ACACCTGAAT TATGCTAAAA CAAAAAACCA AACTGAATGT GACCTGAAAT GCAAGTACAT 1080
CAGAACATAT CTGCAATACC CAAGCCACAG GGAAGAACTT GCAAAACAAC ACAGCTTTTC 1140
AGTTCTGCTC TATCTTACTG CTATGGGGAA TTCACTTCTT CAAAGCAGGA CCTATTTGGA 1200 GCATTACGAT CCACGATTAT TGATGTTGAC ATGTCCATGT AGTAATTTTT CTTCAAGT
Seq ID NO: B59 Protein sequence Protein Accession #-. NP_115942.1
1 11 21 31 41 51
M IPANYTCTRP DIGDNTDFRYF lIYAVTYTVIL VIPGLIGNILA LIWVFYGYMKE TIKRAVIFMIN 60
LAIADLLQVL SLPLRIFYYL NHDWPFGPGL CMFCFYLKYV NMYASIYFLV CISVRRFWFL 120
MYPFRFHDCK QKYDLYISIA GWLIICLACT LFPLLRTSDD TSGNRTKCFV DLPTRNVNLA 180
QSWMMTIGE LIGFVTPLLI VLYCTWKTVL SLQDKYPMAQ DLGEKQKALK MILTCAGVFL 240
ICFAPYHFSF PLDFLVKSNE IKSCLARRVI LIFHSVALCL ASLNSCLDPV IYYFSTNEFR 300
RRLSRQDLHD SIQLHAKSFV SNHTASTMTP ELC
Seq ID NO: B60 DNA sequence
Nucleic Acid Accession #: CAT cluster
1 11 21 31 41 51
I I I I I I
GATTCGGATT TTAATCCGAC TCACTATAGG GAATTTTGGC CCTCGAGGCC AAGAATTCGG 60
CCCGAGGGTT AGACATTTAA CTTGAGTCTT TTCATATCAC GGTATGCTTT TATTTTACCC 120
TCATATATAA TTAATTTTCA TCTGGGCATA TATTTCCAGA TTAGAAATCA TTTCTTTTCA 180
TACATTTTAA GGAATTTATA CATTTGCATC TGAAATTGTA TTCATTATCT TCTAGAAACC 240
AAGAGTGGAC TTGGTATCCG TCTGATTATA TTTTCTTTGT TGGTAAAGAG CCTCTTTTTT 300
CCCTTTTTAT TTTCATCTTC TCTTTCTCTA GTGTTTATAA TCTTATTTTT ATGAATGTAG 360
TCTAATTATT TAGAACACTG TCTCCGAGTA TGTGTTTATT TGGGTTTGTG TTTTGAACAT 420
TGCCTCCAGG TGCGAGTTTA TGTGTGTTTA TGTTTCCTAT TTGAGGTTGG ACACTTAGAA 480
AATTTTCTCA ATTCGAAAAC TATTTTCCTT CAGCACTCAG AAATTTTTAT CAAAGATTAT 540
TTCCACGATT ATTTCCTGTC CTTGGTTTTT CGTGTTCTTA ACCTAGAATT CAATTGTTTA 600 ATGTTAGACC TTACACATCT TCAATGTATC ATATATATTT CACTCATATT ATTTATTGTC 660
ATATCTTTTG GACTATTGTG TGAAAGCAAT AAATGTATAT TACTTTAAAA AAAAAAAAAA 720
AAAACTHCAT TTTCAAATTT AATACACACA AATTGTGCAT ACCCACACAC ATATACCACA 780
GATATATTCA TTTTCAGGAT TTCTTTAAGT GTTATTTTAA AAATAATCAT ATTCTTATTT 840
TGTGAACTGT GGGATTTCTT GAAACTTTTT GAAAACTCTC ATTAGTCTGT GTTTGTGTGG 900
TTTCTTTAAA TTATCTCTTC CTTCAGAATT ACTTTTGTGT TTTGAATTTG AGTCTTTGCC 960
ATTCATAAGG CGGGCTTTCC TTGAATACCA GATAACTCTG AGTTTCCTGT TCATATTTAA 1020
GAATAAATAA CCTAATTTGA AAAAAAAAAA AAAAA Seq ID NO: B61 DNA sequence
Nucleic Acid Accession #: NM_014522.1 Coding sequence: 846..3911
1 11 21 31 41 51
I I I I I I
CTGGTGGTCC AGTACCTCCA AAGATATGGA ATACACTCCT GAAATATCCT GAAAACTTTT 60
TTTTTTCAGA ATCCTTTAAT AAGCAGTTAT GTCAATCTGA AAGTTGCTTA CTTGTACTTT 120
ATATTAATAG CTATTCTTGT TTTTCTTATC CAAAGAAAAA TCCTCTAATC CCCTTTTCAC 180
ATGATAGTTG TTACCATGTT TAGGCATTAG TCACATCAAC CCCTCTCCTC TCCCAAACTT 240
CTCTTCTTCA AATCAAACTT TATTAGTCCC TCCTTTATAA TGATTCCTTG CCTCGTTTTA 300
TCCAGATCAA TTTTTTTTCA CTTTGATGCC CAGAGCTGAA GAAATGGACT ACTGTATAAA 360
TTATTCATTG CCAAGAGAAT AATTGCATTT TAAACCCATA TTATAACAAA GAATAATGAT 420
TATATTTTGT GATTTGTAAC AAATACCCTT TATTTTCCCT TAACTATTGA ATTAAATATT 480
TTAATTATTT GTATTCTCTT TAACTATCTT GGTATATTAA AGTATTATCT TTTATATATT 540
TATCAATGGT GGACACTTTT ATAGGTACTC TGTGTCATTT TTGATACTGT AGGTATCTTA 600
TTTCATTTAT CTTTATTCTT AATGTACGAA TTCATAATAT TTGATTCAGA ACAAATTTAT 660
CACTAATTAA CAGAGTGTCA ATTATGCTAA CATCTCATTT ACTGATTTTA ATTTAAAACA 720
GTTTTTGTTA ACATGCATGT TTAGGGTTGG CTTCTTAATA ATTTCTTCTT CCTCTTCTCT 780
CTCTCCTCTT CTTTTGGTCA GTGTTGTGCG GGTTAATACA ACAAACTGTA ACAAGTGTAC 840
CTGGTATGGA CTTGTTGTCC GGGACGTACA TTTTCGCGGT CCTGCTAGCA TGCGTGGTGT 900
TCCACTCTGG CGCCCAGGAG AAAAACTACA CCATCCGAGA AGAAATGCCA GAAAACGTCC 960
TGATAGGCGA CTTGTTGAAA GACCTTAACT TGTCGCTGAT TCCAAACAAG TCCTTGACAA 1020
CTGCTATGCA GTTCAAGCTA GTGTACAAGA CCGGAGATGT GCCACTGATT CGAATTGAAG 1080
AGGATACTGG TGAGATCTTC ACTACTGGCG CTCGCATTGA TCGTGAGAAA TTATGTGCTG 1140
GTATCCCAAG GGATGAGCAT TGCTTTTATG AAGTGGAGGT TGCCATTTTG CCGGATGAAA 1200
TATTTAGACT GGTTAAGATA CGTTTTCTGA TAGAAGATAT AAATGATAAT GCACCATTGT 1260
TCCCAGCAAC AGTTATCAAC ATATCAATTC CAGAGAACTC GGCTATAAAC TCTAAATATA 1320
CTCTCCCAGC GGCTGTTGAT CCTGACGTAG GAATAAACGG AGTTCAAAAC TACGAACTAA 1380
TTAAGAGTCA AAACATTTTT GGCCTCGATG TCATTGAAAC ACCAGAAGGA GACAAGATGC 1440
CACAACTGAT TGTTCAAAAG GAGTTAGATA GGGAAGAGAA GGATACCTAC GTGATGAAAG 1500
TAAAGGTTGA AGATGGTGGC TTTCCTCAAA GATCCAGTAC TGCTATTTTG CAAGTGAGTG 1560
TTACTGA AC AAATGACAAC CACCCAGTCT TTAAGGAGAC AGAGATTGAA GTCAGTATAC 1620
CAGAAAATGC TCCTGTAGGC ACTTCAGTGA CACAGCTCCA TGCCACAGAT GCTGACATAG 1680
GTGAAAATGC CAAGATCCAC TTCTCTTTCA GCAATCTAGT CTCCAACATT GCCAGGAGAT 1740
TATTTCACCT CAATGCCACC ACTGGACTTA TCACAATCAA AGAACCACTG GATAGGGAAG 1800
AAACACCAAA CCACAAGTTA CTGGTTTTGG CAAGTGATGG TGGATTGATG CCAGCAAGAG 1860
CAATGGTGCT GGTAAATGTT ACAGATGTCA ATGATAATGT CCCATCCATT GACATAAGAT 1920
ACATCGTCAA TCCTGTCAAT GACACAGTTG TTCTTTCAGA AAATATTCCA CTCAACACCA 1980
AAATTGCTCT CATAACTGTG ACGGATAAGG ATGCGGACCA TSATGGCAGG GTGACATGCT 2040
TCACAGATCA TGAAATCCCT TTCAGATTAA GGCCAGTATT CAGTAATCAG TTCCTCCTGG 2100
AGACTGCAGC ATATCTTGAC TATGAGTCCA CAAAAGAATA TGCCATTAAA TTACTGGCTG 2160
CAGATGCTGG CAAACCTCCT TTGAATCAGT CAGCAATGCT CTTCATCAAA GTGAAAGATG 2220
ARAATGACAA TGCTCCAGTT TTCACCCAGT CTTTCGTAAC TGTTTCTATT CCTGAGAATA 2280
ACTCTCCTGG CATCCAGTTG ACGAAAGTAA GTGCAATGGA TGCAGACAGT GGGCCTAATG 2340
CTAAGATCAA TTACCTGCTA GGCCCTGATG CTCCACCTGA ATTCAGCCTG GATTGTCGTA 2400
CAGGCATGCT GACTGTAGTG AAGAAACTAG ATAGAGAAAA AGAGGATAAA TATTTATTCA 2460
CAATTCTGGC AAAAGATAAC GGGGTACCAC CCTTAACCAG CAATGTCACA GTCTTTGTAA 2520
GCATTATTGA TCAGAATGAC AATAGCCCAG TTTTCACTCA CAATGAATAC AACTTCTATG 2580
TCCCAGAAAA CCTTCCAAGG CATGGTACAG TAGGACTAAT CACTGTAACT GATCCTGATT 2640
ATGGAGACAA TTCTGCAGTT ACGCTCTCCA TTTTAGATGA GAATGATGAC TTCACCATTG 2700
ATTCACAAAC TGGTGTCATC CGACCAAATA TTTCATTTGA TAGAGAAAAA CAAGAATCTT 2760
ACACTTTCTA TGTAAAGGCT GAGGATGGTG GTAGAGTATC ACGTTCTTCA AGTGCCAAAG 2820
TAACCATAAA TGTGGTTGAT GTCAATGACA ACAAACCAGT TTTCATTGTC CCTCCTTCCA 2880
ACTGTTCTTA TGAATTGGTT CTACCGTCCA CTAATCCAGG CACAGTGGTC TTTCAGGTAA 2940
TTGCTGTTGA CAATGACACT GGCATGAATG CAGAGGTTCG TTACAGCATT GTAGGAGGAA 3000
ACACARGAGA TCTGTTTGCA ATCGACCAAG AAACAGGCAA CATAACATTG ATGGAGAAAT 3060
GTGATGTTAC AGACCTTGGT TTACACAGAG TGTTGGTCAA AGCTAATGAC TTAGGACAGC 3120
CTGATTCTCT CTTCAGTGTT GTAATTGTCA ATCTGTTCGT GAATGAGTCG GTGACCAATG 3180
CTACACTGAT TAATGAACTG GTGCGCAAAA GCACTGAAGC ACCAGTGACC CCAAATACTG 3240
AGATAGCTGA TGTATCCTCA CCAACTAGTG ACTATGTCAA GATCCTGGTT GCAGCTGTTG 3300
CTGGCACCAT AACTGTCGTT GTAGTTATTT TCATCACTGC TGTAGTAAGA TGTCGCCAGG 3360
CACCACACCT TAAGGCTGCT CAGAAAAACA AGCAGAATTC TGAATGGGCT ACCCCAAACC 3420
CAGAAAACAG GCAGATGATA ATGATGAAGA AAAAGAAAAA GAAGAAGAAG CATTCCCCTA 3480
AGAACTTGCT GCTTAATTTT GTCACTATTG AAGAAACTAA GGCAGATGAT GTTGACAGTG 3540
ATGGAAACAG AGTCACACTA GACCTTCCTA TTGATCTAGA AGAGCAAACA ATGGGAAAGT 3600
ACAATTGGGT AACTACACCT ACTACTTTCA AGCCCGACAG CCCTGATTTG GCCCGACACT 3660
ACAAATCTGC CTCTCCACAG CCTGCCTTCC AAATTCAGCC TGAAACTCCC CTGAATTCGA 3720
AGCACCACAT CATCCAAGAA CTGCCTCTCG ATAACACCTT TGTGGCCTGT GACTCTATCT 3780
CCAAGTGTTC CTCAAGCAGT TCAGATCCCT ACAGCGTTTC TGACTGTGGC TATCCAGTGA 3840
CGACCTTCGA GGTACCTGTG TCCGTACACA CCAGACCGGT AGGTATCCAA GTTTCTAACA 3900
CAACTTTCTA ACTATTTTTT TATTATTATT TTCAGTTGAT GTAGAACTTT ACAAAATCTA 3960
TTGACTTCAA AGAGGGATCA AAACAATCAT ATTCTACAGA TGTACCCAAT AGATATATGG 4020
ATTCAATTAA GTTTGGTAGA AGATGAGAAC AAAATAACTA CTGATTTAGG AAAATTGGAT 4080
GCAGAATAAT AATTATAGTA GGGGCAATTT TGTCTGTAGA TGGCAGTATG ACAATTCTTG 4140 CTAGAGAATA TATTGAAAAA AACTTCAACA CAAAGGGTTG TAGCACTGTC CTCAGTACCA 4200 TTGTGTGCAT GAGGATCAGA ATAGTCTGGG CTAGATACAT CACATTAAAG CTTTTCAGAA 4260 TCTGATAAAT AGCTCTAAAT ACTAATGATA TTGAGAAGCC TAGCTTCACT TGGGAAAATC 4320 TGTGGCTGTT CACAGAAATT CAGCACCAAG TTATTCCCCC CATACTCTAC CAGGCCTTCA 4380 GGTCCTCATA AAGAAAAGTG TCGTTTTCAG ATTAGGAACT CAAAATTATT TTGGTGCATC 4440 AAATCTACAG TCACACAATA TAACAAGAAT GGGATTAGAA AAATGAAAGC CTACTCATTC 4500 TCATCTTTAA GCCAGAGAAT GAAATATATA TGAGGTCTCT GGATAGCTAT TTAAATATTT 4560 GCATATTTAT GCAAGGTATT TTGAGCCCTT CAGAAGACAT TCT
Seq ID NO: B62 Protein sequence Protein Accession #: NP 055337.1
31
MDLLSGTYIF AVLLACWFH SGAQEKNYTI REEMPENVLI GDLLKDLNLS LIPNKSLTTA 60
MQFKLVYKTG DVPLIRIEED TGEIFTTGAR IDREKLCAGI PRDEHCFYEV EVAILPDEIF 120
RLVKIRFLIE DINDNAPLFP ATVINISIPE NSAINSKYTL PAAVDPDVGI NGVQNYELIK 180
SQNIFGLDVI ETPEGDKMPQ LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVT 240
DTNDNHPVFK ETEIEVSIPE NAPVGTSVTQ LHATDADIGE NAKIHFSFSN LVSNIARRLF 300
HLNATTGLIT IKEPLDREET PNHKLLVLAS DGGLMPARAM VLVNVTDVND NVPSIDIRYI 360
VNPVNDTWL SENIPLNTKI ALITVTDKDA DHNGRVTCFT DHEIPFRLRP VFSNQFLLET 420
AAYLDYESTK EYAIKLLAAD AGKPPLNQSA MLFIKVKDEN DNAPVFTQSF VTVSI ENNS 480
PGIQLTKVSA MDADSGPNAK INYLLGPDAP PEFSLDCRTG MLTWKKLDR EKEDKYLFTI 540
LAKDNGVPPL TSNVTVFVSI IDQNDNSPVF THNEYNFYVP ENLPRHGTVG LITVTDPDYG 600
DNSAVTLSIL DENDDFTIDS QTGVIRPNIS FDREKQESYT FYVKAEDGGR VSRSSSAKVT 660
INWDVNDNK PVFIVPPSNC SYELVLPSTN PGTWFQVIA VDNDTGMNAE VRYSI GGNT 720
RDLFAIDQET GNITLMEKCD VTDLGLHRVL VKANDLGQPD SLFSWIVNL FVNESVTNAT 780
LINELVRKST EAPVTPNTEI ADVSSPTSDY VKILVAAVAG TITWWIFI TAWRCRQAP 840
HLKAAQKNKQ NSEWATPNPE NRQMIMMKKK KKKKKHSPKN LLLNFVTIEE TKADDVDSDG 900
NRVTLDLPID LEEQTMGKYN WVTTPTTFKP DSPDLARHYK SASPQPAFQI QPETPLNSKH 960
HI IQELPLDN TFVACDSISK CSSSSSDPYS VSDCGYPVTT FEVPVSVHTR PVGIQVSNTT 1020 F
Seq ID NO: B63 DNA sequence
Nucleic Acid Accession #: XM_059180.2
Coding sequence: 276..3740
1 11 21 31 41 51
I i i 1 i 1 i 1 i 1
GCGGCGGCCG CGGAGTATCC TGGAGCTGCA GACAGTGCGG GCCTGCGCCC AGTCCCGGCT 60
GTCCTCGCCG CGACCCCTCC TCAGCCCTGG GCGCGCGCAC GCTGGGGCCC CGCGGGGCTG 120
GCCGCCTAGC GAGCCTGCCG GTCGACCCCA GCCAGCGCAG CGACGGGGCG CTGCCTGGCC 180
CAGGCGCACA CGGAAGTGCG CTTCTCTGAA GTAGCTTTGG AAAGTAGAGA AGAAAATCCA 240
GTTTGCTTCT TGGAGAACAC TGGACAGCTG AATAAATGCA GTATCTAAAT ATAAAAGAGG 300
ACTGCAATGC CATGGCTTTC TGTGCTAAAA TGAGGAGCTC CAAGAAGACT GAGGTGAACC 360
TGGAGGCCCC TGAGCCAGGG GTGGAAGTGA TCTTCTATCT GTCGGACAGG GAGCCCCTCC 420
GGCTGGGCAG TGGAGAGTAC ACAGCAGAGG AACTGTGCAT CAGGGCTGCA CAGGCATGCC 480
GTATCTCTCC TCTTTGTCAC AACCTCTTTG CCCTGTATGA CGAGAACACC AAGCTCTGGT 540
ATGCTCCAAA TCGCACCATC ACCGTTGATG ACAAGATGTC CCTCCGGCTC CACTACCGGA 600
TGAGGTTCTA TTTCACCAAT TGGCATGGAA CCAACGACAA TGAGCAGTCA GTGTGGCGTC 660
ATTCTCCAAA GAAGCAGAAA AATGGCTACG AGAAAAAAAA GATTCCAGAT GCAACCCCTC 720
TCCTTGATGC CAGCTCACTG GAGTATCTGT TTGCTCAGGG ACAGTATGAT TTGGTGAAAT 780
GCCTGGCTCC TATTCGAGAC CCCAAGACCG AGCAGGATGG ACATGATATT GAGAACGAGT 840
GTCTAGGGAT GGCTGTCCTG GCCATCTCAC ACTATGCCAT GATGAAGAAG ATGCAGTTGC 900
CAGAACTGCC CAAGGACATC AGCTACAAGC GATATATTCC AGAAACATTG AATAAGTCCA 960
TCAGACAGAG GAACCTTCTC ACCAGGATGC GGATAAATAA TGTTTTCAAG GATTTCCTAA 1020
AGGAATTTAA CAACAAGACC ATTTGTGACA GCAGCGTGTC CACGCATGAC CTGAAGGTGA 1080
AATACTTGGC TACCTTGGAA ACTTTGACAA AACATTACGG TGCTGAAATA TTTGAGACTT 1140
CCATGTTACT GATTTCATCA GAAAATGAGA TGAATTGGTT TCATTCGAAT GACGGTGGAA 1200
ACGTTCTCTA CTACGAAGTG ATGGTGACTG GGAATCTTGG AATCCAGTGG AGGCATAAAC 1260
CAAATGTTGT TTCTGTTGAA AAGGAAAAAA ATAAACTGAA GCGGAAAAAA CTGGAAAATA 1320
AACACAAGAA GGATGAGGAG AAAAACAAGA TCCGGGAAGA GTGGAACAAT TTTTCTTACT 1380
TCCCTGAAAT CACTCACATT GTAATAAAGG AGTCTGTGGT CAGCATTAAC AAGCAGGACA 1440
ACAAGAAAAT GGAACTGAAG CTCTCTTCCC ACGAGGAGGC CTTGTCCTTT GTGTCCCTGG 1500
TAGATGGCTA CTTCCGGCTC ACAGCAGATG CCCATCATTA CCTCTGCACC GACGTGGCCC 1560
CCCCGTTGAT CGTCCACAAC ATACAGAATG GCTGTCATGG TCCAATCTGT ACAGAATACG 1620
CCATCAATAA ATTGCGGCAA GAAGGAAGCG AGGAGGGGAT GTACGTGCTG AGGTGGAGCT 1680
GCACCGACTT TGACAACATC CTCATGACCG TCACCTGCTT TGAGAAGTCT GAGCAGGTGC 1740
AGGGTGCCCA GAAGCAGTTC AAGAACTTTC AGATCGAGGT GCAGAAGGGC CGCTACAGTC 1800
TGCACGGTTC GGACCGCAGC TTCCCCAGCT TGGGAGACCT CATGAGCCAC CTCAAGAAGC 1860
AGATCCTGCG CACGGATAAC ATCAGCTTCA TGCTAAAACG CTGCTGCCAG CCCAAGCCCC 1920
GAGAAATCTC CAACCTGCTG GTGGCTACTA AGAAAGCCCA GGAGTGGCAG CCCGTCTACC 1980
CCATGAGCCA GCTGAGTTTC GATCGGATCC TCAAGAAGGA TCTGGTGCAG GGCGAGCACC 2040
TTGGGAGAGG CACGAGAACA CACATCTATT CTGGGACCCT GATGGATTAC AAGGATGACG 2100
AAGGAACTTC TGAAGAGAAG AAGATAAAAG TGATCCTCAA AGTCTTAGAC CCCAGCCACA 2160
GGGATATTTC CCTGGCCTTC TTCGAGGCAG CCAGCATGAT GAGACAGGTC TCCCACAAAC 2220
ACATCGTGTA CCTCTATGGC GTCTGTGTCC GCGACGTGGA GAATATCATG GTGGAAGAGT 2280
TTGTGGAAGG GGGTCCTCTG GATCTCTTCA TGCACCGGAA AAGCGATGTC CTTACCACAC 2340
CATGGAAATT CAAAGTTGCC : AAACAGCTGG CCAGTGCCCT GAGCTACTTG GAGGATAAAG 2400
ACCTGGTCCA TGGAAATGTG t TGTACTAAAA ACCTCCTCCT GGCCCGTGAG GGCATCGACA 2460
GTGAGTGTGG CCCATTCATC 1 AAGCTCAGTG ACCCCGGCAT CCCCATTACG GTGCTGTCTA 2520
GGCAAGAATG CATTGAACGA . ATCCCATGGA TTGCTCCTGA GTGTGTTGAG GACTCCAAGA 2580
ACCTGAGTGT GGCTGCTGAC I AAGTGGAGCT TTGGAACCAC GCTCTGGGAA ATCTGCTACA 2640
ATGGCGAGAT CCCCTTGAAA . GACAAGACGC TGATTGAGAA AGAGAGATTC TATGAAAGCC 2700 GGTGCAGGCC AGTGACACCA TCATGTAAGG AGCTGGCTGA CCTCATGACC CGCTGCATGA 2760 ACTATGACCC CAATCAGAGG CCTTTCTTCC GAGCCATCAT GAGAGACATT AATAAGCTTG 2820 AAGAGCAGAA TCCAGATATT GTTTCAGAAA AAAAACCAGC AACTGAAGTG GACCCCACAC 2880 ATTTTGAAAA GCGCTTCCTA AAGAGGATCC GTGACTTGGG AGAGGGCCAC TTTGGGAAGG 2940 TTGAGCTCTG CAGGTATGAC CCCGAAGGGG ACAATACAGG GGAGCAGGTG GCTGTTAAAT 3000 CTCTGAAGCC TGAGAGTGGA GGTAACCACA TAGCTGATCT GAAAAAGGAA ATCGAGATCT 3060 TAAGGAACCT CTATCATGAG AACATTGTGA AGTACAAAGG AATCTGCACA GAAGACGGAG 3120 GAAATGGTAT TAAGCTCATC ATGGAATTTC TGCCTTCGGG AAGCCTTAAG GAATATCTTC 3180 CAAAGAATAA GAACAAAATA AACCTCAAAC AGCAGCTAAA ATATGCCGTT CAGATTTGTA 3240 AGGGGATGGA CTATTTGGGT TCTCGGCAAT ACGTTCACCG GGACTTGGCA GCAAGAAATG 3300 TCCTTGTTGA GAGTGAACAC CAAGTGAAAA TTGGAGACTT CGGTTTAACC AAAGCAATTG 3360 AAACCGATAA GGAGTATTAC ACCGTCAAGG ATGACCGGGA CAGCCCTGTG TTTTGGTATG 3420 CTCCAGAATG TTTAATGCAA TCTAAATTTT ATATTGCCTC TGACGTCTGG TCTTTTGGAG 3480 TCACTCTGCA TGAGCTGCTG ACTTACTGTG ATTCAGATTC TAGTCCCATG GCTTTGTTCC 3540 TGAAAATGAT AGGCCCAACC CATGGCCAGA TGACAGTCAC AAGACTTGTG AATACGTTAA 3600 AAGAAGGAAA ACGCCTGCCG TGCCCACCTA ACTGTCCAGA TGAGGTTTAT CAACTTATGA 3660 GGAAATGCTG GGAATTCCAA CCATCCAATC GGACAAGCTT TCAGAACCTT ATTGAAGGAT 3720 TTGAAGCACT TTTAAAATAA GAAGCATGAA TAACATTTAA ATTCCACAGA TTATCAAGTC 3780 CTTCTCCTGC AACAAATGCC CAAGTCATTT TTTAAAAATT TCTAATGAAA GAAGTTTGTG 3840 TTCTGTCCAA AAAGTCACTG AACTCATACT TCAGTACATA TACATGTATA AGGCACACTG 3900 TAGTGCTTAA TATGTGTAAG GACTTCCTCT TTAAATTTGG TACCAGTAAC TTAGTGACAC 3960 ATAATGACAA CCAAAATATT TGAAAGCACT TAAGCACTCC TCCTTGTGGA AAGAATATAC 4020 CACCATTTCA TCTGGCTAGT TCACCATCAC AACTGCATTA CCAAAAGGGG ATTTTTGAAA 4080 ACGAGGAGTT GACCAAAATA ATATCTGAAG ATGATTGCTT TTCCCTGCTG CCAGCTGATC 4140 TGAAATGTTT TGCTGGCACA TTAATCATAG ATAAAGAAAG ATTGATGGAC TTAGCCCTCA 4200 AATTTCAGTA TCTATACAGT ACTAGACCAT GCATTCTTAA AATATTAGAT ACCAGGTAGT 4260 ATATATTGTT TCTGTACAAA AATGACTGTA TTCTCTCACC AGTAGGACTT AAACTTTGTT 4320 TCTCCAGTGG CTTAGCTCCT GTTCCTTTGG GTGATCACTA GCACCCATTT TTGAGAAAGC 4380 TGGTTCTACA TGGGGGGATA GCTGTGGAAT AGATAATTTG CTGCATGTTA ATTCTCAAGA 4440 ACTAAGCCTG TGCCAGTGCT TTCCTAAGCA GTATACCTTT AATCAGAACT CATTCCCAGA 4500 ACCTGGATGC TATTACACAT GCTTTTAAGA AACGTCAATG TATATCCTTT TATAACTCTA 4560 CCACTTTGGG GCAAGCTATT CCAGCACTGG TTTTGAATGC TGTATGCAAC CAGTCTGAAT 4620 ACCACATACG CTGCACTGTT CTTAGAGGGT TTCCATACTT ACCACCGATC TACAAGGGTT 4680 GATCCCTGTT TTTACCATCA ATCATCACCC TGTGGTGCAA CACTTGAAAG ACCCGGCTAG 4740 AGGCACTATG GACTTCAGGA TCCACTAGAC AGTTTTCAGT TTGCTTGGAG GTAGCTGGGT 4800 AATCAAAAAT GTTTAGTCAT TGATTCAATG TGAACGATTA CGGTCTTTAT GACCAAGAGT 4860 CTGAAAATCT TTTTGTTATG CTGTTTAGTA TTCGTTTGAT ATTGTTACTT TTCACCTGTT 4920 GAGCCCAAAT TCAGGATTGG TTCAGTGGCA GCAATGAAGT TGCCATTTAA ATTTGTTCAT 4980 AGCCTACATC ACCAAGGTCT CTGTGTCAAA CCTGTGGCCA CTCTATATGC ACTTTGTTTA 5040 CTCTTTATAC AAATAAATAT ACTAAAGACT TT
Seq ID NO: B64 Protein sequence Protein Accession #: A39577
21 31 41 51
1 1 1 1 11 11 1 MQYLNIKEDC NAMAFCAKMR SSKKTEVNLE APEPGVEVIF YLSDREPLRL GSGEYTAEEL 60
CIRAAQACRI SPLCHNLFAL YDENTKLWYA PNRTITVDDK MSLRLHYRMR FYFTNWHGTN 120
DNEQSVWRHS PKKQKNGYEK KKIPDATPLL DASSLEYLFA QGQYDLVKCL APIRDPKTEQ 180
DGHDIENECL GMAVLAISHY AMMKKMQLPE LPKDISYKRY IPETLNKSIR QRNLLTRMRI 240
NNVFKDFLKE FNNKTICDSS VSTHDLKVKY LATLETLTKH YGAEIFETSM LLISSENEMN 300
WFHSNDGGNV LYYEVMVTGN LGIQWRHKPN WSVEKEKNK LKRKKLENKD KKDEEKNKIR 360
EEWNNFSFFP EITHIVIKES WSINKQDNK KMELKLSSHE EALSFVSLVD GYFRLTADAH 420
HYLCTDVAPP LIVHNIQNGC HGPICTEYAI NKLRQEGSEE GMYVLRWSCT DFDNILMTVT 480
CFEKSEQVQG AQKQFKNFQI EVQKGRYSLH GSDRSFPSLG DLMSHLKKQI LRTDNISFML 540
KRCCQPKPRE ISNLLVATKK AQEWQPVYPM SQLSFDRILK KDLVQGEHLG RGTRTHIYSG 600
TLMDYKDDEG TSEEKKIKVI LKVLDPSHRD ISLAFFEAAS MMRQVSHKHI VYLYGVCVRD 660
VENIMVEEFV EGGPLDLFMH RKSDVLTTPW KFKVAKQLAS ALSYLEDKDL VHGNVCTKNL 720
LLAREGIDSE CGPFIKLSDP GIPITVLSRQ ECIERIPWIA PECVEDSKNL SVAADKWSFG 780
TTLWEICYNG EIPLKDKTLI EKERFYESRC RPVTPSCKEL ADLMTRCMNY DPNQRPFFRA 840
IMRDINKLEE QNPDIVSRKK NQPTEVDPTH FEKRFLKRIR DLGEGHFGKV ELCRYDPEDN 900
TGEQVAVKSL KPESGGNHIA DLKKEIEILR NLYHENIVKY KGICTEDGGN GIKLIMEFLP 960
SGSLKEYLPK NKNKINLKQQ LKYAVQICKG MDYLGSRQYV HRDLAARNVL VESEHQVKIG 1020
DFGLTKAIET DKEYYTVKDD RDSPVFWYAP ECLMQSKFYI ASDVWSFGVT LHELLTYCDS 1080
DSSPMALFLK MIGPTHGQMT VTRLVNTLKE GKRLPCPPNC PDEVYQLMRK CWEFQPSNRT 1140
SFQNLIEGFE ALLK
Seq ID NO: B65 DNA sequence Nucleic Acid Accession #: NM_004867.1 Coding sequence: 140. .931
11 21 31 41 51
GATCCCAGAC CTCGGCTTGC AGTAGTGTTA GACTGAAGAT AAAGTAAGTG CTGTTTGGGC 60 TAACAGGATC TCCTCTTGCA GTCTGCAGCC CAGGACGCTG ATTCCAGCAG CGCCTTACCG 120 CGCAGCCCGA AGATTCACTA TGGTGAAAAT CGCCTTCAAT ACCCCTACCG CCGTGCAAAA 180 GGAGGAGGCG CGGCAAGACG TGGAGGCCCT CCTGAGCCGC ACGGTCAGAA CTCAGATACT 240 GACCGGCAAG GAGCTCCGAG TTGCCACCCA GGAAAAAGAG GGCTCCTCTG GGAGATGTAT 300 GCTTACTCTC TTAGGCCTTT CATTCATCTT GGCAGGACTT ATTGTTGGTG GAGCCTGCAT 360 TTACAAGTAC TTCATGCCCA AGAGCACCAT TTACCGTGGA GAGATGTGCT TTTTTGATTC 420 TGAGGATCCT GCAAATTCCC TTCGTGGAGG AGAGCCTAAC TTCCTGCCTG TGACTGAGGA 480 GGCTGACATT CGTGAGGATG ACAACATTGC AATCATTGAT GTGCCTGTCC CCAGTTTCTC 540 TGATAGTGAC CCTGCAGCAA TTATTCATGA CTTTGAAAAG GGAATGACTG CTTACCTGGA 600 CTTGTTGCTG GGGAACTGCT ATCTGATGCC CCTCAATACT TCTATTGTTA TGCCTCCAAA 660 AAATCTGGTA GAGCTCTTTG GCAAACTGGC GAGTGGCAGA TATCTGCCTC AAACTTATGT 720
GGTTCGAGAA GACCTAGTTG CTGTGGAGGA AATTCGTGAT GTTAGTAACC TTGGCATCTT 7B0
TATTTACCAA CTTTGCAATA ACAGAAAGTC CTTCCGCCTT CGTCGCAGAG ACCTCTTGCT 840
GGGTTTCAAC AAACGTGCCA TTGATAAATG CTGGAAGATT AGACACTTCC CCAACGAATT 900
TATTGTTGAG ACCAAGATCT GTCAAGAGTA AGAGGCAACA GATAGAGTGT CCTTGGTAAT 960
AAGAAGTCAβ AGATTTACAA TATGACTTTA ACATTAAGGT TTATGGGATA CTCAAGATAT 1020
TTACTCATGC ATTTACTCTA TTGCTTATGC CGTAAAAAAA AAAAAAAAAA AAAAAAAAAA 1080 AA
Seq ID NO: B66 Protein sequence Protein Accession #: NP_004858.1
1 11 21 31 41 51
I I I I I I
MVKIAFNTPT AVQKEEARQD VEALLSRTVR TQILTGKELR VATQEKEGSS GRCMLTLLGL 60 SFILAGLIVβ GACIYKYFMP KSTIYRGEMC FFDSEDPANS LRGGEPNFLP VTEEADIRED 120 DNIAIIDVPV PSFSDSDPAA IIHDFEKGMT AYLDLLLGNC YLMPLNTSIV MPPKNLVELF 180 GKLASGRYLP QTYWREDLV AVEEIRDVSN LGIFIYQLCN NRKSFRLRRR DLLLGFNKRA 240 IDKCWKIRHF PNEFIVETKI CQE
Seq ID NO : B67 DNA sequence
Nucleic Acid Accession # : XM_083862 .1
Coding sequence : 121 . . 813
11 21 31
ACGCGGGAGG TCTGAGCTGT GGGCTGAGGC AGCGCAGCCG CTGCGCCAGG GTGCGCGATG 60
CCTTGAACCT GGGAAACTAT GTGAAGCAAC ACTCTGGATT TTGAAAGACA TCTTTTCATC 120
ATGGGACAGC AAATTTCGGA TCAGACACAG TTGGTTATTA ACAAGTTACC AGAAAAAGTA 180
GCAAAACATG TTACGTTGGT TCGAGAGAGT GGCTCCTTAA CTTATGAAGA ATTTCTCGGG 240
AGAGTAGCTG AGCTTAATGA TGTAACGGCT AAAGTGGCTT CTGGCCAGGA AAAACATCTT 300
CTCTTTGAGG TACAACCTGG GTCTGATTCC TCTGCTTTTT GGAAAGTGGT TGTACGGGTG 360
GTCTGTACCA AGATTAACAA AAGCAGTGGC ATTGTGGAGG CATCACGGAT CATGAATTTA 420
TACCAGTTTA TTCAACTTTA TAAAGATATC ACAAGTCAAG CAGCAGGAGT ATCGGCACAG 480
AGCTCCACCT CTGAAGAACC TGATGAAAAC TCATCCTCTG TAACATCTTG TCAGGCTAGT 540
CTTTGGATGG GAAGGGTGAA GCAGCTGACC GATGAGGAGG AGTGTTGTAT CTGTATGGAT 600
GGGCGGGCTG ACCTCATCCT GCCTTGTGCT CACAGCTTTT GTCAGAAGTG TATTGATAAA 660
TGGAGTGATC GACACAGGAA TTGCCCTATT TGTCGCCTAC AGATGACTGG AGCAAATGAA 720
TCTTGGGTGG TATCAGATGC ACCCACTGAA GATGATATGG CTAACTATAT TCTTAACATG 780
GCTGATGAGG CAGGCCAGCC CCACAGGCCA TGACCTTGAA GTGAAAGTCT TCTGTTGCTA 840
TTGTGGGCTC AAATATTTGG TCATGGGGGA AGAATGTAGG GTTGTGGCAC TGGCACAGAC 900
ACAGGAAAAT CCATTTTCCC CACTCTTTTA TTTTTGCTAT TCTGATCATT TGTCCCCCTT 960
TTAAAAATAA ACTTCCCATG TCTTCCAAAA AAAAAAAAAA AAAAA
Seq ID NO : B68 Protein sequence Protein Accession # : XP_083862 .1
11 21 31 41 51
I
MGQQISDQTQ LVINKLPEKV AKHVTLVRES GSLTYEEFLG RVAELNDVTA KVASGQEKHL 60 LFEVQPGSDS SAFWKVWRV VCTKINKSSG IVEASRIMNL YQFIQLYKDI TSQAAGVLAQ 120 SSTSEEPDEN SSSVTSCQAS LWMGRVKQLT DEEECCICMD GRADLILPCA HSFCQKCIDK 180 WSDRHRNCPI CRLQMTGANE SWWSDAPTE DDMANYILNM ADEAGQPHRP
Seq ID NO: B69 DNA sequence
Nucleic Acid Accession #: NM_002975.1
Coding sequence: 180..1151
11 21 31
CGACCAACGG ACCGGACAGA GACGAGGAGA GGAACAGGAA GAGAGAAGCT GGGAGAATCG 60
GGAACCTGGG GGCTAGTGAC CTGCACACAG GGCAGGGGCA CTCGGCAGTT CCCAGAGGCC 120
ACCCCTCCCA CCCCAGACAT CCAGACATCT GGAACTTTGG GTGCCAAGAG TCCAGCTTAA 180
TGCAGGCAGC CTGGCTTTTG GGGGCTTTGG TGGTCCCCCA GCTCTTGGGC TTTGGCCATG 240
GGGCTCGGGG AGCAGAGAGG GAGTGGGAGG GAGGCTGGGG AGGTGCCCAG GAGGAGGAGC 300
GGGAGAGGGA GGCCCTGATG CTGAAGCATC TGCAGGAAGC CCTAGGACTG CCTGCTGGGA 360
GGGGGGATGA GAATCCTGCC GGAACTGTTG AGGGAAAAGA GGACTGGGAG ATGGAGGAGG 420
ACCAGGGGGA GGAAGAGGAG GAGGAAGCAA CGCCAACCCC ATCCTCCGGC CCCAGCCCCT 480
CTCCCACCCC TGAGGACATC GTCACTTACA TCCTGGGCCG CCTGGCCGGC CTGGACGCAβ 540
GCCTGCACCA GCTGCACGTC CGTCTGCACG CGTTGGACAC CCGCGTGGTC GAGCTGACCC 600
AGGGGCTGCG GCAGCTGCGG AACGCGGCAG GCGACACCCG CGATGCCGTG CAAGCCCTGC 660
AGGAGGCGCA GGGTCGCGCC GAGCGCGAGC ACGGCCGCTT GGAGGGCTGC CTGAAGGGGC 720
TGCGCCTGGG CCACAAGTGC TTCCTGCTCT CGCGCGACTT CGAAGCTCAG GCGGCGGCGC 780
AGGCGCGGTG CACGGCGCGG GGCGGGAGCC TGGCGCAGCC GGCAGACCGC CAGCAGATGG 840
AGGCGCTCAC TCGGTACCTG CGCGCGGCGC TCGCTCCCTA CAACTGGCCC GTGTGGCTGG 900
GCGTGCACGA TCGGCGCGCC GAGGGCCTCT ACCTCTTCGA AAACGGCCAG CGCGTGTCCT 960
TCTTCGCCTG GCATCGCTCA CCCCGCCCCG AGCTCGGCGC CCAGCCCAGC GCCTCGCCGC 1020
ATCCGCTCAG CCCGGACCAG CCCAACGGTG GCACGCTCGA GAACTGCGTG GCGCAGGCCT 1080
CTGACGACGG CTCCTGGTGG GACCACGACT GCCAGCGGCG TCTCTACTAC GTCTGCGAGT 1140
TCCCCTTCTA GCGGGGCCGG TACCCCGCCT CCTTGCCCAT CCCACCACCC GGCCTTTCCC 1200
TGCGCCGTGC CCACCCTCCT CCGGAATCGC CCTTCCCTTC CTGGCCACGA ATGGCAGCGT 1260
CCTCCCCGAC CCCCAGTCTG GGCGCTTCTG GGAGGGCTCT TGCGGTGCCG GCACTCCTCC 1320
TTGTTAGTGT CTTTCCTTGA AGGGGCGGGC ACCAGGCTAG GTCCGGTGCC AATAAATCCT 1380
TGTGGAATCT GAAAAAAAAA AAAAAAA Seq ID NO: B70 Protein sequence Protein Accession #: NP_002966.1
11 21 31 41 51
I I I I I
MQAAWLLGAL WPQLLGFGH GARGAEREWE GGWGGAQEEE REREALMLKH LQEALGLPAG 60 RGDENPAGTV EGKEDWEMEE DQGEEEEEEA TPTPSSGPSP SPTPEDIVTY ILGRLAGLDA 120 GLHQLHVRLH ALDTRWELT QGLRQLRNAA GDTRDAVQAL QEAQGRAERE HGRLEGCLKG 180 LRLGHKCFLL SRDFEAQAAA QARCTARGGS LAQPADRQQM EALTRYLRAA LAPYNWPVWL 240 GVHDRRAEGL YLFENGQRVS FFAWHRSPRP ELGAQPSASP HPLSPDQPNG GTLENCVAQA 300 SDDGSWWDHD CQRRLYYVCE FPF
Seq ID NO : B71 DNA sequence
Nucleic Acid Accession # : BC000839.1
11 21 31 41 51
I I I I I
CTGGCCAGGG CGACTGGCGG ATAAGGTCTT GTGCGTGGCC TCGAGGCTTA AAAGTAGCAG 60 TGGGGCTTTG TGAAGGACAA AATGGCGATG GCGGGCCGTG TAGGTCCCCC TTCCTATGAT 120 GAGGACCTTT TCACAGACCT GTACTGAGCT CCGTGAGGAT AAGTAACTCT GAGGAGATGG 180 GCCCTGCAAG CCTCCTTCTT AGCCGTCTGT TCAGAAAATA GCGTTTTCGA AATGCCCTGA 240 GTTGACCTAA TGTCTTATTG GGCTCCTGTC TGCAGGATTT ACGCGCACGT TGGAACCGAA 300 GAGAGCTCTG TTGTTGCAAT GTTCAGCCCA CAAGAGCTTA CTGGTGAAGG AATGGGACAA 360 GACCCATCTT TATGCAAAGC CAGCGTTACA GTAATGTTCC AGCATCTCAT AATCTATCCT 420 GGGGAATTCA GCTGCCTCCC AGGGTGAATA CAGGTATTCC TGATGACAGT CTGCCTCTAT 480 CTTACAGAGC AGCTTGTTGC TATATACCAT TGAAAAGCCT TCAGAGCTGA GAGGTACTAC 540 TAACCAATAA CCTGCTTGGC TCAAAGGGCC AGCACCTTCT CTCTAAAGCC CAAGAGGAGT 600 TTGAGGAAAA CTAGGTGTCT GTGTTCACTC CAGGCTGAAG TTACAGGTCT GAGCAAATAA 660 GGTGTATAAA AAATGGAATC TGTCTTGGAG GACATCAGAA GGTGAATTTT CCAAGTTCTT 720 GGACAACCTA GCTGTTGAAA AGCTTTCTGG GTTTGGGGGG TATTTCAGAT GTACCTTAAA 780 GTGTTAGCAG ATACAGATTA AGACACTGGG AGCCAATGAA ACAGCAGTTG AGGGTTTGCT 840 GTGTATCACA TTTCTGTATT TTATCACCCC CTTCCTGCAA CATTATTTAT CTGGAATCTA 900 CCTGCCCTTT TGTTTTTTAG ATACAAGGGC TTGGTTTTGT TACCCAGGCT GGTTTCAAGG 960 CCATAGCTTT AAGAGATCCT CTCACCACAG ATTTCCAAAG TGCTGGGATT GCAGGTGTGA 1020 TTCATGGCAC CCAGACTTTG CTGCCTTTCT TACATGATCC AGGCCCAGAA CCCAAACTCA 1080 GGCACTGTAT AGATGACCAC TTTCGTAAAC TACTGACCTA GCTTGTTGCC AATTGTTGAT 1140 TGAACTTCCC ATAACTCCAC TTCGTGTCTG TTCCTCTGTA TACAGCCACC TTCTGTTCCC 1200 GTCATGAGCC TTTAGGTCTC CATTTGCATA TTGCAAATAC TATGTTCCAT GTAGGTAGCT 1260 CATTCAGGGC CTTGCTCTTC ACTTCAAAAA AGGTTCCCTT GAGGACTGGC TGTCAATTTG 1320 TGTTGCTGTG TTGGTTGTTG ATGAAAATAA TAAAATGATT GATTACATAA AAAAAAAAAA 1380 AAAAAAA
Seq ID NO: B72 DNA sequence
Nucleic Acid Accession #: CAT cluster
11 21 31 41 51
TGCTAGTAGG GCCTGGGTTA ATCGGCCGAG GGTGGCTTCG TGGTCTTTAT AGCTGTTACT 60 CTTTGTACTT GTCTTTTTCT TTTATTTTCT TTTGAGCGAT TGTGCGAACA TAGCATAGCA 120 CGCACTATGG CACGAGGCTC GTGCTGCCTG GCCAGGGCGA CTGGCGGATA AGGTCTTGTG 180 CGTGGCCTCG AGGCTTAAAA GTAGCAGTGG GGCTTTGTGA AGGACAAAAT GGCGATGGCG 240 GGCCGTGTAG GTCCCCCTTC CTATGATGAG GACCTTTTCA CAGACCTGTA CTGAGCTCCG 300 TGAGGATAAA TAACTCTGAG GAGATGGGCC CTGCAAGCCT CTTGCTTAGC CGTCTGTTCA 360 GAAAATAGCG TTTTCGAAAT GCCCTGAGTT GACCTAATGT CTTATTGGGC TCCTGTCTGC 420 AGGATTTACG CGCACGTTGG AACCGAAGAG AGCTCTGTTG TTGCAATGTT CAGCCCACAA 480 GAGCTTACTG GTGAAGGAAT GGGACAAGAC CCATCTTTAT GCAAAGCCAG CGTTACAGTA 540 ATGTTCCAGC ATCTCATAAT CTATCCTGGG GAATTCAGCT GCCTCCCAGG GTGAATACAG 600 GTATTCCTGA TGACAGTCTG CCTCTATCTT ACAGAGCAGC TTGTTGCTAT ATACCATTGA 660 AAAGCCTTCA GAGCTGAGAG GTACTACTAA CCAATAACCT GCTTGGCTCA AAGGGCCAGC 720 ACCTTCTCTC TAAAGCCCAA GAGGAGTTTG AGGAAAACTA GGTGTCTGTG TTCACTCCAG 780 GCTGAAGTTA CAGGTCTGAG CAAATAAGGT GTATAAAAAA TGGAATCTGT CTTGGAGGAC 840 ATCAGAAGGT GAATTTTCCA AGTTCTTGGA CAACCTAGCT GTTGAAAAGC TTTCTGGGTT 900 TGGGGGGTAT TTCAGATGTA CCTTAAAGTG TTAGCAGACA CAGATTAAGA CACTGGGAGC 960 CAATGAAACA GCAGTTGAGG GTTTGCTGTG TATCACATTT CTGTATTTTA TCACCCCCTT 1020 CCTGCAACAT TATTTATCTG GAATCTACCT GCCCTTTTGT TTTTTAGATA CAAGGGCTTG 1080 GTTTTGTTAC CCAGGCTGGT TTCAAGGCCA TAGCTTTAAG AGATCCTCTC ACCACAGATT 1140 TCCAAAGTGC TGGGATTGCA GGTGTGATTC ATGGCACCCA GACTTTGCTG CCTTTCTTAC 1200 ATGATCCAGG CCCAGAACCC AAACTCAGGC ACTGTATAGA TGACCACTTT CGTAAACTAC 1260 TGACCTAGCT TGTTGCCAAT TGTTGATTGA ACTTCCCATA ACTCCACTTC GTGTCTGTTC 1320 CTCTGTATAC AGCCACCTTC TGTTCCCGTC ATGAGCCTTT AGGTCTCCAT TTGCATATTG 1380 CAAATACTAT GTTCCATGTA GGTAGCTCAT TCAGGGCCTT GCTCTTCACT TCAAAAAAGG 1440 TTCCCTTGAG GACTGGCTGT CAATTTGTGT TGCTGTGTTG GTTGTTGATG AAAATAATAA 1500 AATGATTGAT TACATAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAACAAA CACAAAAAAC 1560 CGCCGCGCTT TTTCCCGGGC GCACAAAGTT ATAAAACGCC GTCCATC
Seq ID NO: B73 sequence
Nucleic Acid Accession #: NM_000222.
Coding sequence: 22..2952
11 21 31
GATCCCATCG CAGCTACCGC GATGAGAGGC GCTCGCGGCG CCTGGGATTT TCTCTGCGTT 60 CTGCTCCTAC TGCTTCGCGT CCAGACAGGC TCTTCTCAAC CATCTGTGAG TCCAGGGGAA 120 CCGTCTCCAC CATCCATCCA TCCAGGAAAA TCAGACTTAA TAGTCCGCGT GGGCGACGAG 180
ATTAGGCTGT TATGCACTGA TCCGGGCTTT GTCAAATGGA CTTTTGAGAT CCTGGATGAA 240
ACGAATGAGA ATAAGCAGAA TGAATGGATC ACGGAAAAGG CAGAAGCCAC CAACACCGGC 300
AAATACACGT GCACCAACAA ACACGGCTTA AGCAATTCCA TTTATGTGTT TGTTAGAGAT 360
CCTGCCAAGC TTTTCCTTGT TGACCGCTCC TTGTATGGGA AAGAAGACAA CGACACGCTG 420
GTCCGCTGTC CTCTCACAGA CCCAGAAGTG ACCAATTATT CCCTCAAGGG GTGCCAGGGG 480
AAGCCTCTTC CCAAGGACTT GAGGTTTATT CCTGACCCCA AGGCGGGCAT CATGATCAAA 540
AGTGTGAAAC GCGCCTACCA TCGGCTCTGT CTGCATTGTT CTGTGGACCA GGAGGGCAAβ 600
TCAGTGCTGT CGGAAAAATT CATCCTGAAA GTGAGGCCAG CCTTCAAAGC TGTGCCTGTT 660
GTGTCTGTGT CCAAAGCAAG CTATCTTCTT AGGGAAGGGG AAGAATTCAC AGTGACGTGC 720
ACAATAAAAG ATGTGTCTAG TTCTGTGTAC TCAACGTGGA AAAGAGAAAA CAGTCAGACT 780
AAACTACAGG AGAAATATAA TAGCTGGCAT CACGGTGACT TCAATTATGA ACGTCAGGCA 840
ACGTTGACTA TCAGTTCAGC GAGAGTTAAT GATTCTGGAG TGTTCATGTG TTATGCCAAT 900
AATACTTTTG GATCAGCAAA TGTCACAACA ACCTTGGAAG TAGTAGATAA AGGATTCATT 960
AATATCTTCC CCATGATAAA CACTACAGTA TTTGTAAACG ATGGAGAAAA TGTAGATTTG 1020
ATTGTTGAAT ATGAAGCATT CCCCAAACCT GAACACCAGC AGTGGATCTA TATGAACAGA 1080
ACCTTCACTG ATAAATGGGA AGATTATCCC AAGTCTGAGA ATGAAAGTAA TATCAGATAC 1140
GTAAGTGAAC TTCATCTAAC GAGATTAAAA GGCACCGAAG GAGGCACTTA CACATTCCTA 1200
GTGTCCAATT CTGACGTCAA TGCTGCCATA GCATTTAATG TTTATGTGAA TACAAAACCA 1260
GAAATCCTGA CTTACGACAG GCTCGTGAAT GGCATGCTCC AATGTGTGGC AGCAGGATTC 1320
CCAGAGCCCA CAATAGATTG GTATTTTTGT CCAGGAACTG AGCAGAGATG CTCTGCTTCT 1380
GTACTGCCAG TGGATGTGCA GACACTAAAC TCATCTGGGC CACCGTTTGG AAAGCTAGTG 1440
GTTCAGAGTT CTATAGATTC TAGTGCATTC AAGCACAATG GCACGGTTGA ATGTAAGGCT 1500
TACAACGATG TGGGCAAGAC TTCTGCCTAT TTTAACTTTG CATTTAAAGG TAACAACAAA 1560
GAGCAAATCC ATCCCCACAC CCTGTTCACT CCTTTGCTGA TTGGTTTCGT AATCGTAGCT 1620
GGCATGATGT GCATTATTGT GATGATTCTG ACCTACAAAT ATTTACAGAA ACCCATGTAT 1680
GAAGTACAGT GGAAGGTTGT TGAGGAGATA AATGGAAACA ATTATGTTTA CATAGACCCA 1740
ACACAACTTC CTTATGATCA CAAATGGGAG TTTCCCAGAA ACAGGCTGAG TTTTGGGAAA 1800
ACCCTGGGTG CTGGAGCTTT CGGGAAGGTT GTTGAGGCAA CTGCTTATGG CTTAATTAAG 1860
TCAGATGCGG CCATGACTGT CGCTGTAAAG ATGCTCAAGC CGAGTGCCCA TTTGACAGAA 1920
CGGGAAGCCC TCATGTCTGA ACTCAAAGTC CTGAGTTACC TTGGTAATCA CATGAATATT 1980
GTGAATCTAC TTGGAGCCTG CACCATTGGA GGGCCCACCC TGGTCATTAC AGAATATTGT 2040
TGCTATGGTG ATCTTTTGAA TTTTTTGAGA AGAAAACGTG ATTCATTTAT TTGTTCAAAG 2100
CAGGAAGATC ATGCAGAAGC TGCACTTTAT AAGAATCTTC TGCATTCAAA GGAGTCTTCC 2160
TGCAGCGATA GTACTAATGA GTACATGGAC ATGAAACCTG GAGTTTCTTA TGTTGTCCCA 2220
ACCAAGGCCG ACAAAAGGAG ATCTGTGAGA ATAGGCTCAT ACATAGAAAG AGATGTGACT 2280
CCCGCCATCA TGGAGGATGA CGAGTTGGCC CTAGACTTAG AAGACTTGCT GAGCTTTTCT 2340
TACCAGGTGG CAAAGGGCAT GGCTTTCCTC GCCTCCAAGA ATTGTATTCA CAGAGACTTG 2400
GCAGCCAGAA ATATCCTCCT TACTCATGGT CGGATCACAA AGATTTGTGA TTTTGGTCTA 2460
GCCAGAGACA TCAAGAATGA TTCTAATTAT GTGGTTAAAG GAAACGCTCG ACTACCTGTG 2520
AAGTGGATGG CACCTGAAAG CATTTTCAAC TGTGTATACA CGTTTGAAAG TGACGTCTGG 2580
TCCTATGGGA TTTTTCTTTG GGAGCTGTTC TCTTTAGGAA GCAGCCCCTA TCCTGGAATG 2640
CCGGTCGATT CTAAGTTCTA CAAGATGATC AAGGAAGGCT TCCGGATGCT CAGCCCTGAA 2700
CACGCACCTG CTGAAATGTA TGACATAATG AAGACTTGCT GGGATGCAGA TCCCCTAAAA 2760
AGACCAACAT TCAAGCAAAT TGTTCAGCTA ATTGAGAAGC AGATTTCAGA GAGCACCAAT 2820
CATATTTACT CCAACTTAGC AAACTGCAGC CCCAACCGAC AGAAGCCCGT GGTAGACCAT 2880
TCTGTGCGGA TCAATTCTGT CGGCAGCACC GCTTCCTCCT CCCAGCCTCT GCTTGTGCAC 2940
GACGATGTCT GAGCAGAATC AGTGTTTGGG TCACCCCTCC AGGAATGATC TCTTCTTTTG 3000
GCTTCCATGA TGGTTATTTT CTTTTCTTTC AACTTGCATC CAACTCCAGG ATAGTGGGCA 3060
CCCCACTGCA ATCCTGTCTT TCTGAGCACA CTTTAGTGGC CGATGATTTT TGTCATCAGC 3120
CACCATCCTA TTGCAAAGGT TCCAACTGTA TATATTCCCA ATAGCAACGT AGCTTCTACC 3180
ATGAACAGAA AACATTCTGA TTTGGAAAAA GAGAGGGAGG TATGGACTGG GGGCCAGAGT 3240
CCTTTCCAAG GCTTCTCCAA TTCTGCCCAA AAATATGGTT GATAGTTTAC CTGAATAAAT 3300
GGTAGTAATC ACAGTTGGCC TTCAGAACCA TCCATAGTAG TATGATGATA CAAGATTAGA 3360
AGCTGAAAAC CTAAGTCCTT TATGTGGAAA ACAGAACATC ATTAGAACAA AGGACAGAGT 3420
ATGAACACCT GGGCTTAAGA AATCTAGTAT TTCATGCTGG GAATGAGACA TAGGCCATGA 3480
AAAAAATGAT CCCCAAGTGT GAACAAAAGA TGCTCTTCTG TGGACCACTG CATGAGCTTT 3540
TATACTACCG ACCTGGTTTT TAAATAGAGT TTGCTATTAG AGCATTGAAT TGGAGAGAAG 3600
GCCTCCCTAG CCAGCACTTG TATATACGCA TCTATAAATT GTCCGTGTTC ATACATTTGA 3660
GGGGAAAACA CCATAAGGTT TCGTTTCTGT ATACAACCCT GGCATTATGT CCACTGTGTA 3720
TAGAAGTAGA TTAAGAGCCA TATAAGTTTG AAGGAAACAG TTAATACCAT TTTTTAAGGA 3780
AACAATATAA CCACAAAGCA CAGTTTGAAC AAAATCTCCT CTTTTAGCTG ATGAACTTAT 3840
TCTGTAGATT CTGTGGAACA AGCCTATCAG CTTCAGAATG GCATTGTACT CAATGGATTT 3900
GATGCTGTTT GACAAAGTTA CTGATTCACT GCATGGCTCC CACAGGAGTG GGAAAACACT 3960
GCCATCTTAG TTTGGATTCT TATGTAGCAG GAAATAAAGT ATAGGTTTAG CCTCCTTCGC 4020
AGGCATGTCC TGGACACCGG GCCAGTATCT ATATATGTGT ATGTACGTTT GTATGTGTGT 4080
AGACAAATAT TTGGAGGGGT ATTTTTGCCC TGAGTCCAAG AGGGTCCTTT AGTACCTGAA 4140
AAGTAACTTG GCTTTCATTA TTAGTACTGC TCTTGTTTCT TTTCACATAG CTGTCTAGAG 4200
TAGCTTACCA GAAGCTTCCA TAGTGGTGCA GAGGAAGTGG AAGGCATCAG TCCCTATGTA 4260
TTTGCAGTTC ACCTGCACTT AAGGCACTCT GTTATTTAGA CTCATCTTAC TGTACCTGTT 4320
CCTTAGACCT TCCATAATGC TACTGTCTCA CTGAAACATT TAAATTTTAC CCTTTAGACT 4380
GTAGCCTGGA TATTATTCTT GTAGTTTACC TCTTTAAAAA CAAAACAAAA CAAAACAAAA 4440
AACTCCCCTT CCTCACTGCC CAATATAAAA GGCAAATGTG TACATGGCAG AGTTTGTGTG 4500
TTGTCTTGAA AGATTCAGGT ATGTTGCCTT TATGGTTTCC CCCTTCTACA TTTCTTAGAC 4560
TACATTTAGA GAACTGTGGC CGTTATCTGG AAGTAACCAT TTGCACTGGA GTTCTATGCT 4620
CTCGCACCTT TCCAAAGTTA ACAGATTTTG GGGTTGTGTT GTCACCCAAG AGATTGTTGT 4680
TTGCCATACT TTGTCTGAAA AATTCCTTTG TGTTTCTATT GACTTCAATG ATAGTAAGAA 4740
AAGTGGTTGT TAGTTATAGA TGTCTAGGTA CTTCAGGGGC ACTTCATTGA GAGTTTTGTC 4800
TTGCCATACT TTGTCTGAAA AATTCCTTTG TGTTTCTATT GACTTCAATG ATAGTAAGAA 4860
AAGTGGTTGT TAGTTATAGA TGTCTAGGTA CTTCAGGGGC ACTTCATTGA GAGTTTTGTC 4920
AATGTCTTTT GAATATTCCC AAGCCCATGA GTCCTTGAAA ATATTTTTTA TATATACAGT 4980
AACTTTATGT GTAAATACAT AAGCGGCGTA AGTTTAAAGG ATGTTGGTGT TCCACGTGTT 5040 TTATTCCTGT ATGTTGTCCA ATTGTTGACA GTTCTGAAGA ATTC Seq ID NO: B74 protein sequence Protein Accession #: NP 000213.1
1 11 21 31 41 51
11 1 1 | 1 1 1 1| ] 1 MRGARGAWDF LCVLLLLLRV QTGSSQPSVS PGEPSPPSIH PGKSDLIVRV GDEIRLLCTD 60
PGFVKWTFEI LDETNENKQN EWITEKAEAT NTGKYTCTNK HGLSNSIYVF VRDPAKLFLV 120
DRSLYGKEDN DTLVRCPLTD PEVTNYSLKG CQGKPLPKDL RFIPDPKAGI MIKSVKRAYH 180
RLCLHCSVDQ EGKSVLSEKF ILKVRPAFKA VPWSVSKAS YLLREGEEFT VTCTIKDVSS 240
10 SVYSTWKREN SQTKLQEKYN SWHHGDFNYE RQATLTISSA RVNDSGVFMC YANNTFGSAN 300
VTTTLEWDK GFINIFPMIN TTVFVNDGEN VDLIVEYEAF PKPEHQQWIY MNRTFTDKWE 360
DYPKSENESN IRYVSELHLT RLKGTEGGTY TFLVSNSDVN AAIAFNVYVN TKPEILTYDR 420
LVNGMLQCVA AGFPEPTIDW YFCPGTEQRC SASVLPVDVQ TLNSSGPPFG KLWQSSIDS 480
SAFKHNGTVE CKAYNDVGKT SAYFNFAFKG NNKEQIHPHT LFTPLLIGFV IVAGMMCIIV 540
15 MILTYKYLQK PMYEVQWKW EEINGNNYVY IDPTQLPYDH KWEFPRNRLS FGKTLGAGAF 600
GKWEATAYG LIKSDAAMTV AVKMLKPSAH LTEREALMSE LKVLSYLGNH MNIVNLLGAC 660
TIGGPTLVIT EYCCYGDLLN FLRRKRDSFI CSKQEDHAEA ALYKNLLHSK ESSCΞDSTNE 720
YMDMKPGVSY WPTKADKRR SVRIGSYIER DVTPAIMEDD ELALDLEDLL SFSYQVAKGM 780
AFLASKNCIH RDLAARNILL THGRITKICD FGLARDIKND SNYWKGNAR LPVKWMAPES 840
20 IFNCVΎΓFES DVWSYGIFLW ELFSLGSSPY PGMPVDSKFY KMIKEGFRML SPEHAPAEMY 900
DIMKTCWDAD PLKRPTFKQI VQLIEKQISE STNHIYSNLA NCSPNRQKPV VDHSVRINSV 960
GSTASSSQPL LVHDDV
Seq ID NO: B75 DNA sequence J.D Nucleic Acid Accession #: NM_004456
Coding sequence: 58..2298
11 21 31 41 51
I I I
30 GAATTCCGGG CGACGCGCGG GAACAACGCG AGTCGGCGCG CGGGACGAAG AATAATCATG 60
GGCCAGACTG GGAAGAAATC TGAGAAGGGA CCAGTTTGTT GGCGGAAGCG TGTAAAATCA 120
GAGTACATGC GACTGAGACA GCTCAAGAGG TTCAGACGAG CTGATGAAGT AAAGAGTATG 180
TTTAGTTCCA ATCGTCAGAA AATTTTGGAA AGAACGGAAA TCTTAAACCA AGAATGGAAA 240
CAGCGAAGGA TACAGCCTGT GCACATCCTG ACTTCTGTGA GCTCATTGCG CGGGACTAGG 300
35 GAGTGTTCGG TGACCAGTGA CTTGGATTTT CCAACACAAG TCATCCCATT AAAGACTCTG 360
AATGCAGTTG CTTCAGTACC CATAATGTAT TCTTGGTCTC CCCTACAGCA GAATTTTATG 420
GTGGAAGATG AAACTGTTTT ACATAACATT CCTTATATGG GAGATGAAGT TTTAGATCAG 480
GATGGTACTT TCATTGAAGA ACTAATAAAA AATTATGATG GGAAAGTACA CGGGGATAGA 540
GAATGTGGGT TTATAAATGA TGAAATTTTT GTGGAGTTGG TGAATGCCCT TGGTCAATAT 600
40 AATGATGATG ACGATGATGA TGATGGAGAC GATCCTGAAG AAAGAGAAGA AAAGCAGAAA 660
GATCTGGAGG ATCACCGAGA TGATAAAGAA AGCCGCCCAC CTCGGAAATT TCCTTCTGAT 720
AAAATTTTGG AGGCCATTTC CTCAATGTTT CCAGATAAGG GCACAGCAGA AGAACTAAAG 780
GAAAAATATA AAGAACTCAC CGAACAGCAG CTCCCAGGCG CACTTCCTCC TGAATGTACC 840
CCCAACATAG ATGGACCAAA TGCTAAATCT GTTCAGAGAG AGCAAAGCTT ACACTCCTTT 900
45 CATACGCTTT TCTGTAGGCG ATGTTTTAAA TATGACTGCT TCCTACATCC TTTTCATGCA 960
ACACCCAACA CTTATAAGCG GAAGAACACA GAAACAGCTC TAGACAACAA ACCTTGTGGA 1020
CCACAGTGTT ACCAGCATTT GGAGGGAGCA AAGGAGTTTG CTGCTGCTCT CACCGCTGAG 1080
CGGATAAAGA CCCCACCAAA ACGTCCAGGA GGCCGCAGAA GAGGACGGCT TCCCAATAAC 1140
AGTAGCAGGC CCAGCACCCC CACCATTAAT GTGCTGGAAT CAAAGGATAC AGACAGTGAT 1200
50 AGGGAAGCAG GGACTGAAAC GGGGGGAGAG AACAATGATA AAGAAGAAGA AGAGAAGAAA 1260
GATGAAACTT CGAGCTCCTC TGAAGCAAAT TCTCGGTGTC AAACACCAAT AAAGATGAAG 1320
CCAAATATTG AACCTCCTGA GAATGTGGAG TGGAGTGGTG CTGAAGCCTC AATGTTTAGA 1380
GTCCTCATTG GCACTTACTA TGACAATTTC TGTGCCATTG CTAGGTTAAT TGGGACCAAA 1440
ACATGTAGAC AGGTGTATGA GTTTAGAGTC AAAGAATCTA GCATCATAGC TCCAGCTCCC 1500
55 GCTGAGGATG TGGATACTCC TCCAAGGAAA AAGAAGAGGA AACACCGGTT GTGGGCTGCA 1560
CACTGCAGAA AGATACAGCT GAAAAAGGAC GGCTCCTCTA ACCATGTTTA CAACTATCAA 1620
CCCTGTGATC ATCCACGGCA GCCTTGTGAC AGTTCGTGCC CTTGTGTGAT AGCACAAAAT 1680
TTTTGTGAAA AGTTTTGTCA ATGTAGTTCA GAGTGTCAAA ACCGCTTTCC GGGATGCCGC 1740
TGCAAAGCAC AGTGCAACAC CAAGCAGTGC CCGTGCTACC TGGCTGTCCG AGAGTGTGAC 1800
60 CCTGACCTCT GTCTTACTTG TGGAGCCGCT GACCATTGGG ACAGTAAAAA TGTGTCCTGC 1860
AAGAACTGCA GTATTCAGCG GGGCTCCAAA AAGCATCTAT TGCTGGCACC ATCTGACGTG 1920
GCAGGCTGGG GGATTTTTAT CAAAGATCCT GTGCAGAAAA ATGAATTCAT CTCAGAATAC 1980
TGTGGAGAGA TTATTTCTCA AGATGAAGCT GACAGAAGAG GGAAAGTGTA TGATAAATAC 2040
ATGTGCAGCT TTCTGTTCAA CTTGAACAAT GATTTTGTGG TGGATGCAAC CCGCAAGGGT 2100
65 AACAAAATTC GTTTTGCAAA TCATTCGGTA AATCCAAACT GCTATGCAAA AGTTATGATG 2160
GTTAACGGTG ATCACAGGAT AGGTATTTTT GCCAAGAGAG CCATCCAGAC TGGCGAAGAG 2220
CTGTTTGTTG ATTACAGATA CAGCCAGGCT GATGCCCTGA AGTATGTCGG CATCGAAAGA 2280
GAAATGGAAA TCCCTTGACA TCTGCTACCT CCTCCCCCTC CTCTGAAACA GCTGCCTTAG 2340
CTTCAGGAAC CTCGAGTACT GTGGGCAATT TAGAAAAAGA ACATGCAGTT TGAAATTCTG 2400
70 AATTTGCAAA GTACTGTAAG AATAATTTAT AGTAATGAGT TTAAAAATCA ACTTTTTATT 2460
GCCTTCTCAC CAGCTGCAAA GTGTTTTGTA CCAGTGAATT TTTGCAATAA TGCAGTATGG 2520
TACATTTTTC AACTTTGAAT AAAGAATACT TGAACTTGAA AAAAAAAAAA AAAAAA
Seq ID NO: B76 Protein sequence
75 Protein Accession #: NP 004447
11 21 31 41 51
I I I I I
MGQTGKKSEK GPVCWRKRVK SEYMRLRQLK RFRRADEVKS MFSSNRQKIL ERTEILNQEW 60
80 KQRRIQPVHI LTSVSSLRGT RECSVTSDLD FPTQVIPLKT LNAVASVPIM YSWSPLQQNF 120 MVEDETVLHN IPYMGDEVLD QDGTFIEELI KNYDGKVHGD RECGFINDEI FVELVNALGQ 180 YNDDDDDDDG DDPEEREEKQ KDLEDHRDDK ESRPPRKFPS DKILEAISSM FPDKGTAEEL 240 KEKYKELTEQ QLPGALPPEC TPNIDGPNAK SVQREQSLHS FHTLFCRRCF KYDCFLHPFH 300 ATPNTYKRKN TETALDNKPC GPQCYQHLEG AKEFAAALTA ERIKTPPKRP GGRRRGRLPN 360 NSSRPSTPTI NVLESKDTDS DREAGTETGG ENNDKEEEEK KDETSSSSEA NSRCQTPIKM 420
KPNIEPPENV EWSGAEASMF RVLIGTYYDN FCAIARLIGT KTCRQVYEFR VKESSI IAPA 480
PAEDVDTPPR KKKRKHRLWA AHCRKIQLKK DGSSNHVYNY QPCDHPRQPC DSΞCPCVIAQ 540
NFCEKFCQCS SECQNRFPGC RCKAQCNTKQ CPCYLAVREC DPDLCLTCGA ADHWDSKNVS 600
CKNCSIQRGS KKHLLLAPSD VAGWGIFIKD PVQKNEFISE YCGEIISQDE ADRRGKVYDK 660
YMCSFLFNLN NDFWDATRK GNKIRFANHS VNPNCYAKVM MVNGDHRIGI FAKRAIQTGE 720 ELFVDYRYSQ ADALKYVGIE REMEIP
Seq ID NO : B77 DNA sequence Nucleic Acid Accession # : NM 007015
Coding sequence : 1 . . 1005
1 11 21 31 41 51
I I I I I I
ATGACAGAGA ACTCCGACAA AGTTCCCATT GCCCTGGTGG GACCTGATGA CGTGGAATTC 60
TGCAGCCCCC CGGCGTACGC TACGCTGACG GTGAAGCCCT CCAGCCCCGC GCGGCTGCTC 120
AAGGTGGGAG CCGTGGTCCT CATTTCGGGA GCTGTGCTGC TGCTCTTTGG GGCCATCGGG 180
GCCTTCTACT TCTGGAAGGβ GAGCGACAGT CACATTTACA ATGTCCATTA CACCATGAGT 240
ATCAATGGGA AACTACAAGA TGGGTCAATG GAAATAGACG CTGGGAACAA CTTGGAGACC 300
TTTAAAATGG GAAGTGGAGC TGAAGAAGCA ATTGCAGTTA ATGATTTCCA GAATGGCATC 360
ACAGGAATTC GTTTTGCTGG AGGAGAGAAG TGCTACATTA AAGCGCAAGT GAAGGCTCGT 420
ATTCCTGAGG TGGGCGCCGT GACCAAACAG AGCATCTCCT CCAAACTGGA AGGCAAGATC 480
ATGCCAGTCA AATATGAAGA AAATTCTCTT ATCTGGGTGG CTGTAGATCA GCCTGTGAAG 540
GACAACAGCT TCTTGAGTTC TAAGGTGTTA GAACTCTGCG GTGACCTTCC TATTTTCTGG 600
CTTAAACCAA CCTATCCAAA AGAAATCCAG AGGGAAAGAA GAGAAGTGGT AAGAAAAATT 660
GTTCCAACTA CCACAAAAAG ACCACACAGT GGACCACGGA GCAACCCAGG CGCTGGAAGA 720
CTGAATAATG AAACCAGACC CAGTGTTCAA GAGGACTCAC AAGCCTTCAA TCCTGATAAT 780
CCTTATCATC AGCAGGAAGG GGAAAGCATG ACATTCGACC CTAGACTGGA TCACGAAGGA 840
ATCTGTTGTA TAGAATGTAG GCGGAGCTAC ACCCACTGCC AGAAGATCTG TGAACCCCTG 900
GGGGGCTATT ACCCATGGCC TTATAATTAT CAAGGCTGCC GTTCGGCCTG CAGAGTCATC 960
ATGCCATGTA GCTGGTGGGT GGCCCGTATC TTGGGCATGG TGTGAAATCA CTTCATATAT 1020
CACGTGCTGT AAAATAAGAA CTAGCTGAAG AGACAACCAA AGAAGCATTA AGGCAGGTTG 1080
ATGCTGATGG GACCATAAAA TATTTTTACA CGCAGCCTGA GCGGTTATTC TTGACACTCT 1140
TAACAGAATT TTTTTAATCG TTTTCCAGAA CTTTAGTATA TGCAAATGCA CTGAAAGGGT 1200
AGTTCAAGTC TAAAATGCCA TAACCCCGTT ATTTGTTATT TTTTATTTGC ATTGATTTGC 1260
CATAAGTCTT CCCTTGCTTG CATCTTCCAA AGCTATTTCG AAATAAACAC GAAAATTTAC 1320 AGTTTGCC
Seq ID NO: B78 Protein sequence Protein Accession #: NP 008946
1 11 21 31 41 51
I I 1 I I I
MTENSDKVPI ALVGPDDVEF CSPPAYATLT VKPSSPARLL KVGAWLISG AVLLLFGAIG 60
AFYFWKGSDS HIYNVHYTMS INGKLQDGSM EIDAGNNLET FKMGSGAEEA IAVNDFQNGI 120
TGIRFAGGEK CYIKAQVKAR IPEVGAVTKQ SISSKLEGKI MPVKYEENSL IWVAVDQPVK 180
DNSFLSSKVL ELCGDLPIFW LKPTYPKEIQ RERREWRKI VPTTTKRPHS GPRSNPGAGR 240
LNNETRPSVQ EDSQAFNPDN PYHQQEGESM TFDPRLDHEG ICCIECRRSY THCQKICEPL 300
GGYYPWPYNY QGCRSACRVI MPCSWWVARI LGMV
Seq ID NO: B79 DNA sequence
Nucleic Acid Accession #: NM_012449.1
Coding sequence: 66..1085
1 11 21 31 41 51 l l l l l !
CCGAGACTCA CGGTCAAGCT AAGGCGAAGA GTGGGTGGCT GAAGCCATAC TATTTTATAG 60
AATTAATGGA AAGCAGAAAA GACATCACAA ACCAAGAAGA ACTTTGGAAA ATGAAGCCTA 120
GGAGAAATTT AGAAGAAGAC GATTATTTGC ATAAGGACAC GGGAGAGACC AGCATGCTAA 180
AAAGACCTGT GCTTTTGCAT TTGCACCAAA CAGCCCATGC TGATGAATTT GACTGCCCTT 240
CAGAACTTCA GCACACACAG GAACTCTTTC CACAGTGGCA CTTGCCAATT AAAATAGCTG 300
CTATTATAGC ATCTCTGACT TTTCTTTACA CTCTTCTGAG GGAAGTAATT CACCCTTTAG 360
CAACTTCCCA TCAACAATAT TTTTATAAAA TTCCAATCCT GGTCATCAAC AAAGTCTTGC 420
CAATGGTTTC CATCACTCTC TTGGCATTGG TTTACCTGCC AGGTGTGATA GCAGCAATTG 480
TCCAACTTCA TAATGGAACC AAGTATAAGA AGTTTCCACA TTGGTTGGAT AAGTGGATGT 540
TAACAAGAAA GCAGTTTGGG CTTCTCAGTT TCTTTTTTGC TGTACTGCAT GCAATTTATA 600
GTCTGTCTTA CCCAATGAGG CGATCCTACA GATACAAGTT GCTAAACTGG GCATATCAAC 660
AGGTCCAACA AAATAAAGAA GATGCCTGGA TTGAGCATGA TGTTTGGAGA ATGGAGATTT 720
ATGTGTCTCT GGGAATTGTG GGATTGGCAA TACTGGCTCT GTTGGCTGTG ACATCTATTC 780
CATCTGTGAG TGACTCTTTG ACATGGAGAG AATTTCACTA TATTCAGAGC AAGCTAGGAA 840
TTGTTTCCCT TCTACTGGGC ACAATACACG CATTGATTTT TGCCTGGAAT AAGTGGATAG 900
ATATAAAACA ATTTGTATGG TATACACCTC CAACTTTTAT GATAGCTGTT TTCCTTCCAA 960
TTGTTGTCCT GATATTTAAA AGCATACTAT TCCTGCCATG CTTGAGGAAG AAGATACTGA 1020
AGATTAGACA TGGTTGGGAA GACGTCACCA AAATTAACAA AACTGAGATA TGTTCCCAGT 1080
TGTAGAATTA CTGTTTACAC ACATTTTTGT TCAATATTGA TATATTTTAT CACCAACATT 1140 TCAAGTTTGT ATTTGTTAAT AAAATGATTA TTCAAGGAAA AAAAAAAAAA AAAAA
Seq ID NO: B80 Protein sequence Protein Accession #: NP_036581.1
1 11 21 31 41 51
I I I I I I
MESRKDITNQ EELWKMKPRR NLEEDDYLHK DTGETSMLKR PVLLHLHQTA HADEFDCPSE 60
LQHTQELFPQ WHLPIKIAAI IASLTFLYTL LREVIHPLAT SHQQYFYKIP ILVINKVLPM 120 VSITLLALVY LPGVIAAIVQ LHNGTKYKKF PHWLDKWMLT RKQFGLLSFF FAVLHAIYSL 180
SYPMRRSYRY KLLNWAYQQV QQNKEDAWIE HDVWRMEIYV SLGIVGLAIL ALLAVTSIPS 240
VSDSLTWREF HYIQSKLGIV SLLLGTIHAL IFAWNKWIDI KQFVWYTPPT FMIAVFLPIV 300 VLIFKSILFL PCLRKKILKI RHGWEDVTKI NKTEICSQL
Seq ID NO : B81 DNA sequence Nucleic Acid Accession # : NM_000684 Coding sequence : 87 . .1520
21 31 51
TGCTACCCGC GCCCGGGCTT CTGGGGTGTT CCCCAACCAC GGCCCAGCCC TβCCACACCC 60
CCCGCCCCCG GCCTCCGCAG CTCGGCATGG GCGCGGGGGT GCTCGTCCTG GGCGCCTCCβ 120
AGCCCGGTAA CCTGTCGTCG GCCGCACCGC TCCCCGACGG CGCGGCCACC βCβGCGCGGC 180
TGCTGGTGCC CGCGTCGCCG CCCGCCTCGT TGCTGCCTCC CGCCAGCGAA AGCCCCGAGC 240
CGCTGTCTCA GCAGTGGACA GCGGGCATGG GTCTGCTGAT GGCGCTCATC GTGCTGCTCA 300
TCGTGGCGGG CAATGTGCTG GTGATCGTGG CCATCGCCAA GACGCCGCGG CTGCAGACGC 360
TCACCAACCT CTTCATCATG TCCCTGGCCA GCGCCGACCT GGTCATGGGG CTGCTGGTGG 420
TGCCGTTCGG GGCCACCATC GTGGTGTGGG GCCGCTGGGA GTACGGCTCC TTCTTCTGCG 480
AGCTGTGGAC CTCAGTGGAC GTGCTGTGCG TGACGGCCAG CATCGAGACC CTGTGTGTCA 540
TTGCCCTGGA CCGCTACCTC GCCATCACCT CGCCCTTCCG CTACCAGAGC CTGCTGACGC 600
GCGCGCGGGC GCGGGGCCTC GTGTGCACCG TGTGGGCCAT CTCGGCCCTG GTGTCCTTCC 660
TGCCCATCCT CATGCACTGG TGGCGGGCGG AGAGCGACGA GGCGCGCCGC TGCTACAACG 720
ACCCCAAGTG CTGCGACTTC GTCACCAACC GGGCCTACGC CATCGCCTCG TCCGTAGTCT 780
CCTTCTACGT GCCCCTGTGC ATCATGGCCT TCGTGTACCT GCGGGTGTTC CGCGAGGCCC 840
AGAAGCAGGT GAAGAAGATC GACAGCTGCG AGCGCCGTTT CCTCGGCGGC CCAGCGCGGC 900
CGCCCTCGCC CTCGCCCTCG CCCGTCCCCG CGCCCGCGCC GCCGCCCGGA CCCCCGCGCC 960
CCGCCGCCGC CGCCGCCACC GCCCCGCTGG CCAACGGGCG TGCGGGTAAG CGGCGGCCCT 1020
CGCGCCTCGT GGCCCTACGC GAGCAGAAGG CGCTCAAGAC GCTGβGCATC ATCATGGGCG 1080
TCTTCACGCT CTGCTGGCTG CCCTTCTTCC TGGCCAACGT GGTGAAGGCC TTCCACCGCG 1140
AGCTGGTGCC CGACCGCCTC TTCGTCTTCT TCAACTGGCT GGGCTACGCC AACTCGGCCT 1200
TCAACCCCAT CATCTACTGC CGCAGCCCCG ACTTCCGCAA GGCCTTCCAG GGACTGCTCT 1260
GCTGCGCGCG CAGGGCTGCC CGCCGGCGCC ACGCGACCCA CGGAGACCGG CCGCGCGCCT 1320
CGGGCTGTCT GGCCCGGCCC GGACCCCCGC CATCGCCCGG GGCCGCCTCG βACGACGACG 1380
ACGACGATGT CGTCGGGGCC ACGCCGCCCG CGCGCCTGCT GGAGCCCTGG GCCGGCTGCA 1440
ACGGCGGGGC GGCGGCGGAC AGCGACTCGA GCCTGGACGA GCCGTGCCβC CCCGGCTTCG 1500
CCTCGGAATC CAAGGTGTAG GGCCCGGCGC GGGGCGCGGA CTCCGGGCAC GGCTTCCCAG 1560
GGGAACGAGG AGATCTGTGT TTACTTAAGA CCGATAGCAG GTGAACTCβA AGCCCACAAT 1620
CCTCGTCTGA ATCATCCGAG GCAAAGAGAA AAGCCACGGA CCGTTGCACA AAAAGGAAAG 1680
TTTGGGAAGG GATGGGAGAG TGGCTTGCTG ATGTTCCTTG TTG
Seq ID NO: B82 Protein sequence Protein Accession #: NP_000675.1
1 11 21 31 41 51
MGAGVLVLGA SEPGNLSSAA PLPDβAATAA RLLVPASPPA SLLPPASESP EPLSQQWTAG 60
MGLLMALIVL LIVAGNVLVI VAIAKTPRLQ TLTNLFIMSL ASADLVMGLL WPFGATIW 120
WGRWEYGSFF CELWTSVDVL CVTASIETLC VIALDRYLAI TSPFRYQSLL TRARARGLVC 180
TVWAISALVS FLPILMHWWR AESDEARRCY NDPKCCDFVT NRAYAIASSV VSFYVPLCIM 240
AFVYLRVFRE AQKQVKKIDS CERRFLGGPA RPPSPSPSPV PAPAPPPGPP RPAAAAATAP 300
LANGRAGKRR PSRLVALREQ KALKTLGIIM GVFTLCWLPF FLANWKAFH RELVPDRLFV 360
FFNWLGYANS AFNPIIYCRS PDFRKAFQGL LCCARRAARR RHATHGDRPR ASGCLARPGP 420
PPSPGAASDD DDDDWβATP PARLLEPWAG CNGGAAADSD SSLDEPCRPG FASESKV
Seq ID NO: B83 DNA sequence
Nucleic Acid Accession #: NM_000729.2
Coding sequence: 2..421
11 21 31 41 51
GGCTCAGCTG CCGGGCTGCT CCGGTTGGAA ACGCCAAGCC AGCTGCCGTC CTAATCCAAA 60 AGCCATGAAC AGCGGCGTGT GCCTGTGCGT GCTGATGGCG GTACTGGCGG CTGGCGCCCT 120 GACGCAGCCG GTGCCTCCCG CAβATCCCGC GGGCTCCGGG CTGCAGCGGG CAGAGGAGGC 180 GCCCCGTAGG CAGCTGAGGG TATCGCAGAG AACGGATGGC GAGTCCCGAG CGCACCTGGG 240 CGCCCTGCTG GCAAGATACA TCCAGCAGGC CCGGAAAGCT CCTTCTGGAC GAATGTCCAT 300 CGTTAAGAAC CTGCAGAACC TGGACCCCAG CCACAGGATA AGTGACCββG ACTACATGGG 360 CTGGATGGAT TTTGGCCGTC GCAGTGCCGA GGAGTATGAG TACCCCTCCT AGAGGACCCA 420 GCCGCCATCA GCCCAACGGA AGCAACCTCC CAACCCAGAG GAGGCAGAAT AAGACAACAA 480 TCACACTCAT AACTCATTGT CTGTGGAGTT TGACATTGAA TGTATCTATT TATTAAGTTC 540 TCAATGTGAA AATTGTGTCT GTAAGATTGT CCAGTGCAAC CACACACGCT CACCAGAAGT 600 TGTGCAAACT GAAGACAAAA CTGTTTTCTT CATCTGTGAC TCCTGTTCTG AAAATGTTGT 660 TATGCTATTA AAGTGATTTC ATTCTGCC
Seq ID NO: B84 Protein sequence Protein Accession #: NP 000720.1
1 11 21 31 41 51
I I I I 1 I
MNSGVCLCVL MAVLAAGALT QPVPPADPAG SβLQRAEEAP RRQLRVSQRT DGESRAHLGA 60
LLARYIQQAR KAPSGRMSIV KNLQNLDPSH RISDRDYMGW MDFGRRSAEE YEYPS TABLE 74 Gene Sequences Up- or Down-Regulated in Cancer Angiogenesis
Al DNA SEQUENCE Gene name: endothelial differentiation, sphmgolip d G-protem-coupled receptor, 1 Unigene number Hs.154210 Probeset Accession #• M31210 Nucleic Acid Accession # M31210 Coding sequence 251-1396
TCTAAAGGTC GGGGGCAGCA GCAAGATGCG AAGCGAGCCG TACAGATCCC GGGCTCTCCG 60 AACGCAACTT CGCCCTGCTT GAGCGAGGCT GCGGTTTCCG AGGCCCTCTC CAGCCAAGGA 120 AAAGCTACAC AAAAAGCCTG GATCACTCAT CGAACCACCC CTGAAβCCAG TGAAGGCTCT 180 CTCGCCTCGC CCTCTAGCGT TCGTCTGGAG TAGCGCCACC CCGGCTTCCT GGGGACACAG 240 GGTTGGCACC ATGGGβCCCA CCAGCGTCCC GCTGGTCAAG GCCCACCGCA GCTCGGTCTC 300 TGACTACGTC AACTATGATA TCATCGTCCG GCATTACAAC TACACGGGAA AGCTGAATAT 360 CAGCGCGGAC AAGGAGAACA GCATTAAACT GACCTCGGTG GTGTTCATTC TCATCTGCTG 420 CTTTATCATC CTGGAGAACA TCTTTGTCTT GCTGACCATT TGGAAAACCA AGAAATTCCA 480 CCGACCCATG TACTATTTTA TTGGCAATCT G6CCCTCTCA GACCTGTTGG CAGGAGTAGC 540 CTACACAGCT AACCTGCTCT TGTCTGGGGC CACCACCTAC AAGCTCACTC CCβCCCAβTβ 600 GTTTCTGCGG GAAGGGAGTA TGTTTGTGGC CCTGTCAGCC TCCGTGTTCA GTCTCCTCGC 660 CATCGCCATT GAGCGCTATA TCACAATGCT GAAAATGAAA CTCCACAACG GGAGCAATAA 720 CTTCCGCCTC TTCCTGCTAA TCAGCGCCTG CTGGβTCATC TCCCTCATCC TGGGTGGCCT 780 GCCTATCATG GβCTGGAACT GCATCAGTGC GCTGTCCAGC TGCTCCACCβ TGCTGCCGCT 840 CTACCACAAG CACTATATCC TCTTCTGCAC CACGGTCTTC ACTCTGCTTC TGCTCTCCAT 900 CGTCATTCTG TACTGCAGAA TCTACTCCTT GGTCAGGACT CGβAGCCGCC GCCTGACGTT 960 CCGCAAGAAC ATTTCCAAGG CCAGCCGCAG CTCTGAGAAT βTGGCGCTGC TCAAGACCGT 1020 AATTATCGTC CTGAGCGTCT TCATCGCCTG CTGGGCACCG CTCTTCATCC TGCTCCTGCT 1080 GGATGTGGGC TGCAAββTGA AGACCTGTGA CATCCTCTTC AGAGCGGAGT ACTTCCTGβT 1140 GTTAGCTGTG CTCAACTCCG GCACCAACCC CATCATTTAC ACTCTGACCA ACAAGGAGAT 1200 GCGTCGGGCC TTCATCCGGA TCATGTCCTG CTGCAAGTGC CCGAGCGGAG ACTCTGCTGG 1260 CAAATTCAAG CGACCCATCA TCGCCββCAT GGAATTCAGC CGCAGCAAAT CGGACAATTC 1320 CTCCCACCCC CAGAAAGACG AAGGGGACAA CCCAGAGACC ATTATGTCTT CTGGAAACGT 1380 CAACTCTTCT TCCTAGAACT GGAAGCTGTC CACCCACCGG AAGCGCTCTT TACTTGβTCG 1440 CTGGCCACCC CAβTGTTTGG AAAAAAATCT CTGGGCTTCG ACTGCTGCCA GGGAGGAGCT 1500 GCTGCAAGCC AGAGGGAGGA AGGGGGAGAA TACGAACAGC CTGGTGGTGT CGGGTGTTGG 1560 TGGGTAGAGT TAβTTCCTGT GAACAATGCA CTGGGAAGGG TGGAGATCAG GTCCCGGCCT 1620 GβAATATATA TTCTACCCCC CTGGAβCTTT GATTTTGCAC TGAGCCAAAG GTCTAGCATT 1680 GTCAAGCTCC TAAAGGGTTC ATTTGGCCCC TCCTCAAAGA CTAATGTCCC CATGTGAAAG 1740 CGTCTCTTTG TCTGGAGCTT TGAGGAGATG TTTTCCTTCA CTTTAGTTTC AAACCCAAGT 1800 GAGTGTGTGC ACTTCTGCTT CTTTAGGGAT GCCCTGTACA TCCCACACCC CACCCTCCCT 1860 TCCCTTCATA CCCCTCCTCA ACGTTCTTTT ACTTTATACT TTAACTACCT GAGAGTTATC 1920 AGAGCTGGGG TTGTGGAATG ATCGATCATC TATAGCAAAT AGGCTATGTT GAGTACGTAG 1980 GCTGTGGGAA GATGAAGATG GTTTGGAGGT GTAAAACAAT GTCCTTCGCT GAGGCCAAAG 2040 TTTCCATGTA AGCGGGATCC GTTTTTTβGA ATTTGGTTGA AGTCACTTTG ATTTCTTTAA 2100 AAAACATCTT TTCAATGAAA TGTGTTACCA TTTCATATCC ATTGAAGCCG AAATCTGCAT 2160 AAGGAAGCCC ACTTTATCTA AATGATATTA GCCAGGATCC TTGGTGTCCT AGGAGAAACA 2220 GACAAGCAAA ACAAAGTGAA AACCGAATGG ATTAACTTTT GCAAACCAAG GGAGATTTCT 2280 TAGCAAATGA GTCTAACAAA TATGACATCC GTCTTTCCCA CTTTTGTTGA TGTTTATTTC 2340 AGAATCTTGT GTGATTCATT TCAAGCAACA ACATGTTGTA TTTTGTTGTG TTAAAAGTAC 2400 TTTTCTTGAT TTTTGAATGT ATTTGTTTCA GGAAGAAGTC ATTTTATGGA TTTTTCTAAC 2460 CCGTGTTAAC TTTTCTAGAA TCCACCCTCT TGTGCCCTTA AGCATTACTT TAACTGGTAG 2520 GGAACGCCAG AACTTTTAAG TCCAGCTATT CATTAGATAG TAATTGAAGA TATGTATAAA 2580 TATTACAAAG AATAAAAATA TATTACTGTC TCTTTAGTAT GGTTTTCAGT GCAATTAAAC 2640 CGAGAGATGT CTTGTTTTTT TAAAAAGAAT AGTATTTAAT AGGTTTCTGA CTTTTGTGGA 2700 TCATTTTGCA CATAGCTTTA TCAACTTTTA AACATTAATA AACTGATTTT TTTAAAG
A2 Protein sequence: Gene name: endothelial differentiation, sphmgolipid G-protem-coupled receptor, 1 Unigene number: Hs.154210 Probeset Accession #: M31210 Protem Accession #: AAA52336 Signal sequence: none found Transmembrane domains: 50-71, 92-110, 122-140, 160-177, 202-222, 251-269, 283-301 Cellular Localization: plasma membrane
1 11 21 31 41 51 1 1 |1 I 1 1 1 | 1 I 1 MGPTSVPLVK AHRSSVSDYV NYDIIVRHYN YTGKLNISAD KENSIKLTSV VFILICCFII 60
LENIFVLLTI WKTKKFHRPM YYFIGNLALS DLLAGVAYTA NLLLSGATTY KLTPAQWFLR 120
EGSMFVALSA SVFSLLAIAI ERYITMLKMK LHNGSNNFRL FLLISACWVI SLILGGLPIM 180
GWNCISALSS CSTVLPLYHK HYILFCTTVF TLLLLSIVIL YCRIYSLVRT RSRRLTFRKN 240
ISKASRSSEN VALLKTVIIV LSVFIACWAP LFILLLLDVG CKVKTCDILF RAEYFLVLAV 300
LNSGTNPIIY TLTNKEMRRA FIRIMSCCKC PSGDSAGKFK RPIIAGMEFS RSKSDNSSHP 360
QKDEGDNPET IMSSGNVNSS S
A3 DNA SEQUENCE
Gene name: G protem-coupled receptor 51 Unigene number- Hs.198612 Probeset Accession # - AA452928 Nucleic Acid Accession # NM 004624 1 Coding sequence : 1-2826 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
ATGGCTTCCC CGCGGAGGTC CGGGCAGCCA GGGCGGCCGC CGCCGCCGCC ACCGCCGCCC 60
GCGCGCCTGC TACTGCTACT GCTGCTGCCG CTGCTGCTGC CTCTGGCGCC CGGGβCCTββ 120
GGCTGGGCGC GGGGCGCCCC CCGGCCGCCG CCCAGCAGCC CGCCGCTCTC CATCATGGGC 180
CTCATGCCGC TCACCAAGGA GGTGGCCAAG GGCAGCATCG GβCGCGGTGT GCTCCCCGCC 240
GTβGAACTGG CCATCGAGCA GATCCGCAAC GAGTCACTCC TGCGCCCCTA CTTCCTCGAC 300
CTGCββCTCT ATGACACGGA βTGCGACAAC GCAAAAGGGT TGAAAGCCTT CTACGATGCA 360
ATAAAATACG GGCCGAACCA CTTGATGGTG TTTGβAGGCG TCTGTCCATC CβTCACATCC 420
ATCATTGCAG AGTCCCTCCA AGGCTGGAAT CTGGTGCAGC TTTCTTTTGC TGCAACCACG 480
CCTGTTCTAG CCβATAAβAA AAAATACCCT TATTTCTTTC GGACCGTCCC ATCAGACAAT 540
GCGβTGAATC CAGCCATTCT GAAGTTGCTC AAGCACTACC AGTGβAAGCG CGTβGGCACG 600
CTGACβCAAG ACGTTCAGAG GTTCTCTGAG GTGCGGAATG ACCTGACTGG AGTTCTGTAT 660
GGCGAβGACA TTGAGATTTC AGACACCGAG AGCTTCTCCA ACGATCCCTG TACCAGTGTC 720
AAAAAGCTGA AGGGGAATGA TGTGCGGATC ATCCTTGGCC AβTTTβACCA GAATATGGCA 780
GCAAAAGTβT TCTβTTGTGC ATACGAGGAG AACATGTATG βTAGTAAATA TCAGTGGATC 840
ATTCCGGGCT GGTACGAGCC TTCTTGGTGG GAGCAGGTGC ACACGβAAGC CAACTCATCC 900
CGCTGCCTCC βGAAGAATCT βCTTβCTGCC ATGGAGGGCT ACATTGGCGT GGATTTCGAG 960
CCCCTGAGCT CCAAGCAGAT CAAβACCATC TCAβGAAAGA CTCCACAGCA GTATGAGAGA 1020
GAGTACAACA ACAAGCGGTC AGGCGTGGββ CCCAGCAAGT TCCACGGGTA CGCCTACβAT 1080
GGCATCTGGG TCATCGCCAA GACACTGCAG AGGGCCATGG AβACACTβCA TβCCAGCAGC 1140
CGGCACCAβC GGATCCAGGA CTTCAACTAC ACGGACCACA CGCTGGβCAG GATCATCCTC 1200
AATβCCATβA ACGAGACCAA CTTCTTCGGG GTCACβGGTC AAβTTβTATT CCGGAATGGG 1260
GAGAGAATGG GGACCATTAA ATTTACTCAA TTTCAAGACA βCAGGGAGGT GAAβGTGGGA 1320
GAGTACAACG CTGTGGCCGA CACACTGGAG ATCATCAATG ACACCATCAG GTTCCAAGβA 1380
TCCGAACCAC CAAAAGACAA GACCATCATC CTGGAGCAGC TGCGGAAGAT CTCCCTACCT 1440
CTCTACA6CA TCCTCTCTGC CCTCACCATC CTCGβGATGA TCATGGCCAβ TGCTTTTCTC 1500
TTCTTCAACA TCAAGAACCG GAATCAGAAβ CTCATAAAGA TGTCGAGTCC ATACATGAAC 1560
AACCTTATCA TCCTTGGAGG GATGCTCTCC TATGCTTCCA TATTTCTCTT TGGCCTTGAT 1620
GGATCCTTTG TCTCTGAAAA GACCTTTGAA ACACTTTGCA CCGTCAGGAC CTGGATTCTC 1680
ACCGTββGCT ACACGACCGC TTTTGGGGCC ATGTTTGCAA AGACCTGGAG AGTCCACβCC 1740
ATCTTCAAAA ATGTGAAAAT GAAGAAGAAG ATCATCAAβG ACCAGAAACT GCTTGTGATC 1800
GTGGGGGGCA TGCTGCTGAT CGACCTGTGT ATCCTGATCT GCTGGCAGGC TGTGGACCCC 1860
CTGCGAAGGA CAGTβGAGAA GTACAGCATG GAGCCGGACC CAGCAGGACG GGATATCTCC 1920
ATCCβCCCTC TCCTGGAGCA CTGTGAGAAC ACCCATATGA CCATCTGGCT TβGCATCGTC 1980
TATβCCTACA AGGβACTTCT CATGTTGTTC GGTTGTTTCT TAGCTTGβGA GACCCGCAAC 2040
GTCAGCATCC CCGCACTCAA CβACAβCAAβ TACATCGGGA TGAGTGTCTA CAACGTGGGG 2100
ATCATGTGCA TCATCGGGGC CCCTGTCTCC TTCCTGACCC ββGACCAGCC CAATGTGCAG 2160
TTCTGCATCG TβGCTCTGGT CATCATCTTC TGCAGCACCA TCACCCTCTβ CCTGGTATTC 2220
GTGCCGAAβC TCATCACCCT GAGAACAAAC CCAGATGCAG CAACGCAGAA CAGGCGATTC 2280
CAGTTCACTC AGAATCAGAA GAAAGAAGAT TCTAAAACGT CCACCTCGGT CACCAGTGTG 2340
AACCAAGCCA GCACATCCCG CCTGGAβGGC CTACAGTCAG AAAACCATCG CCTGCGAATG 2400
AAGATCACAG AGCTGGATAA AGACTTβGAA GAGGTCACCA TGCAGCTGCA GGACACACCA 2460
GAAAAβACCA CCTACATTAA ACAGAACCAC TACCAAGAGC TCAATGACAT CCTCAACCTG 2520
GGAAACTTCA CTGAGAGCAC AGATGGAGGA AAGβCCATTT TAAAAAATCA CCTCGATCAA 2580
AATCCCCAGC TACAGTGGAA CACAACAGAG CCCTCTCGAA CATGCAAAGA TCCTATAGAA 2640
GATATAAACT CTCCAGAACA CATCCAGCGT CGGCTGTCCC TCCAGCTCCC CATCCTCCAC 2700
CACGCCTACC TCCCATCCAT CGGAGGCGTG GACGCCAGCT GTGTCAGCCC CTGCGTCAβC 2760
CCCACCGCCA GCCCCCGCCA CAGACATGTG CCACCCTCCT TCCGAGTCAT GGTCTCGGGC 2820
CTGTAA
A4 Protein sequence: Gene name: G protein-coupled receptor 51 Unigene number: Hs.198612 Probeset Accession #: AA452928 Protein Accession #: NP_005449.1 Signal sequence: 1-42 Pfam domains: 7tm_3 [481-754] , ANF_receptor [130-204] Transmembrane domains: 22-44, 477-499, 517-539, 552-574, 595-617, 653-675, 692-713, 722-744 Cellular Localization: plasma membrane
11 21 31 41 51
MASPRRSGQP G IRPPPPPPPP A IRLLLLLLLP L ILLPLAPGAW β IWARGAPRPP P ISSPPLSIMG 60 LMPLTKEVAK GSIGRGVLPA VELAIEQIRN ESLLRPYFLD LRLYDTECDN AKGLKAFYDA 120 IKYGPNHLMV FGGVCPSVTS IIAESLQGWN LVQLSFAATT PVLADKKKYP YFFRTVPSDN 180 AVNPAILKLL KHYQWKRVGT LTQDVQRFSE VRNDLTGVLY GEDIEISDTE SFSNDPCTSV 240 KKLKGNDVRI ILβQFDQNMA AKVFCCAYEE NMYGSKYQWI IPGWYEPSWW EQVHTEANSS 300 RCLRKNLLAA MEGYIGVDFE PLSSKQIKTI SβKTPQQYER EYNNKRSGVG PSKFHGYAYD 360 GIWVIAKTLQ RAMETLHASS RHQRIQDFNY TDHTLGRIIL NAMNETNFFG VTGQWFRNG 420 ERMGTIKFTQ FQDSREVKVG EYNAVADTLE IINDTIRFQG SEPPKDKTII LEQLRKISLP 480 LYSILSALTI LβMIMASAFL FFNIKNRNQK LIKMSSPYMN NLIILGGMLS YASIFLFGLD 540 GSFVSEKTFE TLCTVRTWIL TVGYTTAFGA MFAKTWRVHA IFKNVKMKKK IIKDQKLLVI 600 VGGMLLIDLC ILICWQAVDP LRRTVEKYSM EPDPAGRDIS IRPLLEHCEN THMTIWLGIV 660 YAYKGLLMLF GCFLAWETRN VSIPALNDSK YIGMSVYNVG IMCIIGAAVS FLTRDQPNVQ 720 FCIVALVIIF CSTITLCLVF VPKLITLRTN PDAATQNRRF QFTQNQKKED SKTSTSVTSV 780 NQASTSRLEG LQSENHRLRM KITELDKDLE EVTMQLQDTP EKTTYIKQNH YQELNDILNL 840 GNFTESTDGG KAILKNHLDQ NPQLQWNTTE PSRTCKDPIE DINSPEHIQR RLSLQLPILH 900 HAYLPSIGGV DASCVSPCVS PTASPRHRHV PPSFRVMVSG L A5 DNA SEQUENCE Gene name : ESTs Unigene number: Hs.293616 Probeset Accession #: AW043782 Nucleic Acid Accession #: none found
Coding sequence: 38-1075 (underlined sequence corresponds to start and stop codon)
1 11 21 31 41 51
I I I I I I
AGCAACGACG CCGGβCAGCG GGAβCββCGG CCGCβCCATβ TβGCTGCTββ GGCCGCTGTG 60
CCTGCTGCTG AGCAGCGCCG CGGAβAβCCA βCTGCTCCCC GGβAACAACT TCACCAATGA 120
GTGCAACATA CCAGβCAACT TCATGTGCAG CAATGGACGG TGCATCCCGG GCGCCTGGCA 180
GTGTGACGGG CTGCCTGACT GCTTCGACAA GAGTβATGAG AAGGAGTβCC CCAAββCTAA 240 βTCGAAATGT GGCCCAACCT TCTTCCCCTG TGCCAGCGGC ATCCATTGCA TCATTββTCG 300
CTTCCGGTGC AATGGGTTTG AGGACTβTCC CGATββCAGC GATGAAGAGA ACTβCACAGC 360
AAACCCTCTG CTTTGCTCCA CCGCCCGCTA CCACTβCAAG AACGGCCTCT GTATTGACAA 420
GAGCTTCATC TGCGATGGAC AGAATAACTG TCAAGACAAC AGTGATGAGβ AAAβCTβTβA 480
AAGTTCTCAA GAACCCGβCA GTGGβCAGGT GTTTGTGACT TCAGAGAACC AACTTGTGTA 540
TTACCCCAGC ATCACCTATG CCATCATCGG CAGCTCCGTC ATTTTTGTGC TGGTGGTGGC 600
CCTGCTGGCA CTGGTCTTGC ACCACCAGCG GAAGCββAAC AACCTCATGA CGCTGCCCGT 660
GCACCGGCTG CAGCACCCTG TGCTGCTGTC CCGCCTGβTG GTCCT6GACC ACCCCCACCA 720
CTGCAACGTC ACCTACAACG TCAATAATGG CATCCAGTAT GTGGCCAβCC AGGCGGAβCA 780 βAATβCβTCG GAAβTAGGCT CCCCACCCTC CTACTCCGAG GCCTTGCTGG ACCAβAGGCC 840
TGCGTGβTAT βACCTTCCTC CACCGCCCTA CTCTTCTGAC ACGGAATCTC TGAACCAAGC 900
CGACCTGCCC CCCTACCGCT CCCGGTCCGG GAGTβCCAAC AGTGCCAGCT CCCAGGCAGC 960
CAGCAGCCTC CTGAGCGTGG AAGACACCAC CCACAβCCCβ ββGCAGCCTG GCCCCCAGGA 1020
GGGCACTGCT GAGCCCAGGG ACTCTGAGCC CAGCCAβββC ACTGAAGAAG TATAAGTCCC 1080
AGTTATTCCA AAGTCCATAT ββGTTAATCT GCTCTGACTT GTTGCCATTC TAACAATTTG 1140
TGCTCATGGG AAGCTCTTTA AGCACCTGTA AGβATβTCTC AAGTTACAGT TTGGGATATT 1200
AACTATCTCT GCATTCCCCT CCTCCCCCAG ACTTCAGAGA TGTTTTTCTG GCGTCTCAGT 1260
TGACATGATC TGTTGTGCGT CTTTTCTGTC AGβTCACTCT TCCCTTGGGA CCCGAGATCA 1320
CACCCTCATT TTTCACATTA TTCTGTTTCT GTTββAβAβA CACCATATAA AACAβTATTG 1380
AAATAGGCTG GGAGAGAGCA ATGTTTCTGT GCTATATTGβ ATGCTCAGAA βTGCAGβAβA 1440
CGCTGGACCC AATTCTCTCT GCTGGGTAGT TACCTTATAG CATTTGGGGA TTTGβGTTAG 1500
ATGATCTAAC CAGGAGGCCA TCACTGGATG GTCACCCCCC CAAAAAAATT CCATTTGAGC 1560
ATCAAAACCT GCTTTGCACA ATCCTATTTG ATGCCCCCAG TTCACCAβAβ TCAβTββCCA 1620
AAβAAAACTT TGGACGTGAG TAACACCCTT CAGCAGTCCC AACβTTATTT TGGTTTTGTG 1680
AAGGACTCTG AAACCATCTA CCCTGTATAA ATTCTGβCTT TAβAAATTTG CCCAAGAATG 1740
CTCATTCTGA GAGCTTTCCT CAβCACCATA TATCATCAGC CTCATCCTAA AATAGGCACβ 1800
GAGCCCCTCC CATGAGTTTA TCCAAβTTCT CAGCTCCTAA AATGCAGGCT GCCAAβACCC 1860
TACACCTβCC CTβGCTCTAC AGCCACTTAC CTGGTTTCTG GACTGTCACC CTCCCAGCTG 1920
ACCTGCCCGT AGCCAAGGAA TGAGGACCTA ACTTGAGTTG GCCCAAAGTC TGACCTGGCT 1980
GTATGTCCCT GTGβCCCACA CCCAβCCTGT CTTGCTCATT CATGCAβCCT CAACACTGβC 2040
CTCCAAAGTT CCCTTAACAC TTGCAAAGTC CTTTTTACCT GTGCATTTGG ACTTβAGGAC 2100
ACTGGTTTCT ATCACAββTG AGAGCCATGT TCAATACCTC CAGCAAGCTC TCCTGβCTCC 2160
CTGCACTGTG CACGCTCCTC TTCCCAAGβT CCCAATACCA GCACCTCTAG TTAGAGTTAG 2220
GGTCAGGGTC AGGCCTCTCC CAACATCCCA GTAGTTTCTC CTCTGAGACA CATGGGCAAG 2280
AGACAATTTG GAGTCAAGAT TTTCCATTTG βATCTATTTT AAATCTTTTA GAAATGCATT 2340
TGAAACAGTG TGTTTGTTTT TTCCCTTCTA GTTAAGGβAC TATTTATATG TGTATAGGAA 2400
AGCTGTCTCT TTTTTTGTTT TTCCTTTAAC AAGGTCCAAA GAAAGATGCA AAAGGAGATC 2460
ACACCCTTGC CCCGCTGAGC CCCGTGATAA CAAGTCACTC CAGACTAACC TGTGTGCCAG 2520
ACATTTGTGC ATTGTTGCAC TTTGAGGTTA TTATTTATCA AGTTCTTGAA GGAAGCAGAA 2580
AGAββGACTC CTCTCTCCCT CCGTGTATAG TCTCTATGTT TβTGCTAGTT TTTCTTTTTT 2640
TTCTCTGTβT CCAGTCAGCC ACAGGGCCCG CCTCCCTGCA GGAATAAGGG GTAAAACGTT 2700
AGGTGTTGTT TGβCAAβAAA CCACACTGAC TGATGAGGGG TAAAATGGAA CCAGGTAβAG 2760
CCACTCCGGG CAGCTGTCAC CCATTCAGAA CTTCTTTCCG CAGCTGAAGA AATGTTCAGT 2820
AACCTGTTTG ACGCTAATTA AAACAGAGCC TGCAGGAAGT GGGGCTAAAG TGGCATTCAβ 2880
TGATCCTGTT CTGTAGACTT TTCTTTCTTT TTTTAACCAA ATCCAAAGGA TGTTACAGAA 2940
AAGCTAGCCA CTGGTATTTT GTTTTGTTTA AAAAAAAAAA GAAAGAAAGA AAGAAAGAAA 3000
AACβGAAAGβ AACCTAGCTG CCTGTATCTT TCATTTTTAA AATAGCACTT GAGTTATTTT 3060
CTGAGTAATC CAATAAAGAA CTTTTβATβA CAGCCAGAAT GTGTTAGAAC TCTGGCTGAA 3120
CATTTCATCT CCTGTGAGTC AGAAGGGCTT TATTTCTCCC TTTGATGGGG CCCCTTCTTC 3180
TTTCTGβTβC TCTGGAAGTT GTTTAGAGGA AAGAATTCTA ATTTTAATTA ATTGCGCAGT 3240
GAGTTAATCT CACTCGCTTT TCTGCTTCCA GGCATCTTAG GAAAAACAAA TGGTTTTAGT 3300
AGATAAGGGA TGCCTACTAA TGCTTTTTTA AAACAAACAG GGACATTTTT ATTATAGATT 3360
TGATTTTTTT AATβAATGTT TTTAAAAATA TATAAATAGβ ACACCAAACC GGCAGGGTTT 3420
TTTTTGGGGG GAGGGGGTTT GTTTTCCAAC TCAAGATGβC ACATTAGTGG CCAGCAATAT 3480
TTTTTAACTC ATTCCAACCA GGAAGCTTTT TTATACATTG CCTAAATCTA CGCCAACCAG 3540
AAAATAGTCT CATCTCTTTT TTTCTCAAAT GAGATCCGTG TTTTATTTTA GCATTAAATT 3600
AGTTACACTβ TGATGACTGG CCTATTACCT GACTCAGCTC CCTCTACCTT GAAATTGACA 3660
TTTTTAAAAA ATGCAACTAA GTGGTTAATA GTGTGTGACG CTCAAAβTTA ATGTAAACTG 3720
GAAAGGTTGT GTGTCβTTGC TTTTTGTGTT TTGGTTAGGC TTββTTTTβT TTTTTAATTT 3780
TTATACTTTC TAATAAATTT βCAGTTTCAT TCTTTCTGTT TGTGCAAAWG GWMCTAMARM 3840
AAMMAAAAAC AWYWTTGβββ GGGCTTGGGC CTCGGAAAAA GTTTTTAACA CCACTTCGGG 3900
TβGGGCGGCG GGGCCCACβT AGGTACGGCG ACCACGCGGG CCCAAACCGG ACCCCAGAAG 3960
GAAACCCTGG CCAAGAAAAA GGTGGCGAGA ATTCTCCACA CCAGAAAAAA ACβCβCCβββ 4020
GGAAACCGCA GAGTGTTGCG TAAACCACAC CCGAAGAGAG AACTCAGAAG CACACAAGCG 4080 GGACTCAACC AGGAGβACCC AAGGGAACCC GATAGAGTAC G
A6 Protein sequence : Gene name: Unigene number: Hs.293616 Probeset Accession #: AW043782 Protein Accession #: none found Signal sequence: 1-17 Transmembrane domains: 169-191 LDLa domains : 28-66, 70-108, 112-149 Cellular Localization-. plasma membrane
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I I I I I
MWLLGPLCLL LSSAAESQLL PGNNFTNECN IPGNFMCSNG RCIPGAWQCD βLPDCFDKSD 60 EKECPKAKSK CGPTFFPCAS βlHCIIGRFR CNGFEDCPDG SDEENCTANP LLCSTARYHC 120 KNGLCIDKSF ICDGQNNCQD NSDEESCESS QEPGSGQVFV TSENQLVYYP SITYAIIGSS 180 VIFVLWALL ALVLHHQRKR NNLMTLPVHR LQHPVLLSRL WLDHPHHCN VTYNVNNGIQ 240 YVASQAEQNA SEVGSPPSYS EALLDQRPAW YDLPPPPYSS DTESLNQADL PPYRSRSGSA 300 NSASSQAASS LLSVEDTSHS PGQPGPQEGT AEPRDSEPSQ GTEEV
A7 DNA SEQUENCE Gene name: Integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Unigene number: HS.149609 Probeset Accession #: X06256 Nucleic Acid Accession # : NM_002205 Coding sequence: 1-3150 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
ATGGββAβCC GGACGCCAGA GTCCCCTCTC CACGCCGTGC AGCTGCβCTβ GGGCCCCCGG 60
CGCCGACCCC CGCTSSTGCC GCTGCTGTTG CTGCTSSTGC CGCCGCCACC CAGGGTCGGG 120 βGCTTCAACT TAGACGCGGA GGCCCCAGCA GTACTCTCGG GGCCCCCGGG CTCCTTCTTC 180
GGATTCTCAG TGGAGTTTTA CCGGCCGGGA ACAGACGGGG TCAGTGTGCT GGTββGAGCA 240
CCCAAGGCTA ATACCAβCCA GCCAGGAβTG CTGCAGGGTG GTGCTGTCTA CCTCTGTCCT 300
TGββGTGCCA GCCCCACACA GTGCACCCCC ATTGAATTTG ACAGCAAAGG CTCTCGGCTC 360
CTββAβTCCT CACTGTCCAG CTCAGAGGGA GAGGAGCCTG TGGAGTACAA GTCCTTGCAG 420
TGβTTCβGGG CAACAGTTCG AGCCCATGGC TCCTCCATCT TGGCATGCGC TCCACTGTAC 480
AGCTGGCGCA CAGAGAAGGA GCCACTGAGC GACCCCGTGG GCACCTGCTA CCTCTCCACA 540
GATAACTTCA CCCGAATTCT GβAGTATGCA CCCTGCCGCT CAGATTTCAG CTGβGCAGCA 600
GGACAGβGTT ACTGCCAAGβ AGGCTTCAGT GCCGAGTTCA CCAAGACTGG CCGTGTGGTT 660
TTAGGTGGAC CAββAAβCTA TTTCTββCAA GGCCAGATCC TGTCTGCCAC TCAGGAGCAG 720
ATTGCAGAAT CTTATTACCC CGAGTACCTG ATCAACCTGG TTCAGGGGCA GCTGCAGACT 780
CGCCAGGCCA GTTCCATCTA TGATGACAGC TACCTAβGAT ACTCTGTGGC TβTTGGTGAA 840
TTCAGTGGTG ATGACACAGA AGACTTTGTT GCTGGTGTGC CCAAAGGGAA CCTCACTTAC 900
GGCTATGTCA CCATCCTTAA TGGCTCAGAC ATTCGATCCC TCTACAACTT CTCAGGGGAA 960
CAGATGGCCT CCTACTTTGG CTATGCAGTG GCCGCCACAG ACβTCAATGG GGACGGGCTG 1020
GATGACTTGC TCGTGGGGGC ACCCCTGCTC ATGGATCGGA CCCCTGACGG GCGGCCTCAG 1080
GAGGTGGGCA GGGTCTACβT CTACCTGCAG CACCCAGCCG GCATAGAGCC CACβCCCACC 1140
CTTACCCTCA CTGβCCATGA TGAGTTTGGC CβATTTGGCA GCTCCTTGAC CCCCCTβGGG 1200
GACCTGGACC AGGATGGCTA CAATGATGTG GCCATCGGGG CTCCCTTTGG TGGGGAGACC 1260
CAGCAGGGAG TAGTGTTTGT ATTTCCTGGG GGCCCAGGAG GGCTGGGCTC TAAGCCTTCC 1320
CAGGTTCTGC AGCCCCTGTG GGCAGCCAGC CACACCCCAG ACTTCTTTGG CTCTGCCCTT 1380
CGAGβAGGCC GAGACCTGGA TGGCAATGGA TATCCTGATC TGATTGTGGG GTCCTTTGGT 1440
GTGGACAAGG CTGTGGTATA CAGGGβCCβC CCCATCGTGT CCGCTAGTGC CTCCCTCACC 1500
ATCTTCCCCG CCATGTTCAA CCCAGAGGAG CGGAGCTGCA GCTTAGAGGG GAACCCTGTG 1560
GCCTGCATCA ACCTTAGCTT CTGCCTCAAT GCTTCTGGAA AACACGTTGC TGACTCCATT 1620
GGTTTCACAβ TβGAACTTCA GCTGGACTGG CAGAAβCAGA AGβGAGGGβT ACGGCGGGCA 1680
CTGTTCCTGG CCTCCAGGCA GGCAACCCTG ACCCAβACCC TβCTCATCCA GAATGGGGCT 1740
CGAGAGGATT βCAGAGAGAT GAAGATCTAC CTCAββAACG AGTCAGAATT TCGAGACAAA 1800
CTCTCGCCGA TTCACATCGC TCTCAACTTC TCCTTGGACC CCCAAGCCCC AGTGGACAGC 1860
CACGGCCTCA GCCCAGCCCT ACATTATCAβ AGCAAGAGCC GGATAβAGGA CAAGGCTCAG 1920
ATCTTGCTββ ACTGTβGAGA AGACAACATC TGTGTGCCTG ACCTβCAGCT GGAAβTGTTT 1980
GGGGAGCAGA ACCATGTGTA CCTGβGTGAC AAGAATGCCC TGAACCTCAC TTTCCATGCC 2040
CAGAATβTGG GTGAGGβTGG CGCCTATGAG GCTGAGCTTC GGGTCACCβC CCCTCCAGAG 2100
GCTGAGTACT CAGGACTCGT CAGACACCCA GGGAACTTCT CCAGCCTGAG CTGTGACTAC 2160
TTTGCCGTGA ACCAGAGCCG CCTGCTGGTβ TGTGACCTGG GCAACCCCAT GAAGGCAGGA 2220
GCCAGTCTGT GGGGTGGCCT TCGGTTTACA GTCCCTCATC TCCGGGACAC TAAGAAAACC 2280
ATCCAGTTTG ACTTCCAGAT CCTCAGCAAG AATCTCAACA ACTCGCAAAβ CβACGTGGTT 2340
TCCTTTCGGC TCTCCGTβGA GGCTCAGGCC CAGGTCACCC TGAACββTGT CTCCAAGCCT 2400
GAGGCAGTGC TATTCCCAGT AAGCGACTGG CATCCCCGAG ACCAGCCTCA GAAGGAGGAG 2460
GACCTGGGAC CTGCTGTCCA CCATGTCTAT GAGCTCATCA ACCAAββCCC CAGCTCCATT 2520
AGCCAGGGTG TGCTGGAACT CAGCTGTCCC CAGGCTCTGG AAGGTCAGCA GCTCCTATAT 2580
GTGACCAGAG TTACβGGACT CAACTGCACC ACCAATCACC CCATTAACCC AAAGGGCCTβ 2640
GAGTTGGATC CCGAGGGTTC CCTGCACCAC CAGCAAAAAC GGGAAGCTCC AAGCCβCAGC 2700
TCTGCTTCCT CGGGACCTCA GATCCTGAAA TGCCCGGAGG CTGAGTGTTT CAGGCTGCGC 2760
TGTGAGCTCG GGCCCCTGCA CCAACAAGAG AGCCAAAGTC TGCAGTTGCA TTTCCβAGTC 2820
TGGGCCAAGA CTTTCTTGCA βCGGGAGCAC CAGCCATTTA GCCTGCAGTβ TGAGGCTGTG 2880
TACAAAGCCC TGAAGATGCC CTACCGAATC CTGCCTCGGC AGCTGCCCCA AAAAGAGCGT 2940
CAGGTGGCCA CAGCTβTGCA ATGGACCAAβ GCAGAAGGCA GCTATGGCGT CCCACTGTGG 3000
ATCATCATCC TAGCCATCCT GTTTGβCCTC CTGCTCCTAG GTCTACTCAT CTACATCCTC 3060
TACAAGCTTG GATTCTTCAA ACGCTCCCTC CCATATβGCA CCGCCATGGA AAAAGCTCAG 3120 CTCAAβCCTC CAGCCACCTC TGATGCCTGA A8 Protein sequence: Gene name: Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) Unigene number: Hs.149609 Probeset Accession # : X06256 Protein Accession # : NP_002196 Signal sequence : 1-42 Transmembrane domains : 998-1020
Integrin alpha domains: 56-115, 268-318, 322-384, 388-444, 452-503, 1022-1036 Cellular Localization: plasma membrane
11 31 51
MGSRTPESPL HAVQLRWGPR RRPPLLPLLL LLLPPPPRVG GFNLDAEAPA VLSGPPGSFF 60
GFSVEFYRPG TDGVSVLVGA PKANTSQPGV LQGGAVYLCP WGASPTQCTP IEFDSKGSRL 120
LESSLSSSEG EEPVEYKSLQ WFGATVRAHG SSILACAPLY SWRTEKEPLS DPVGTCYLST 180
DNFTRILEYA PCRSDFSWAA GQGYCQGGFS AEFTKTGRW LGGPβSYFWQ GQILSATQEQ 240
IAESYYPEYL INLVQGQLQT RQASSIYDDS YLGYSVAVGE FSβDDTEDFV AGVPKGNLTY 300
GYVTILNGSD IRSLYNFSβE QMASYFGYAV AATDVNGDGL DDLLVGAPLL MDRTPDGRPQ 360
EVGRVYVYLQ HPAGIEPTPT LTLTGHDEFG RFGSSLTPLG DLDQDGYNDV AIGAPFGGET 420
QQGWFVFPG GPGGLGSKPS QVLQPLWAAS HTPDFFGSAL RGGRDLDGNG YPDLIVGSFG 480
VDKAWYRGR PIVSASASLT IFPAMFNPEE RSCSLEGNPV ACINLSFCLN ASGKHVADSI 540
GFTVELQLDW QKQKGGVRRA LFLASRQATL TQTLLIQNGA REDCREMKIY LRNESEFRDK 600
LSPIHIALNF SLDPQAPVDS HGLRPALHYQ SKSRIEDKAQ ILLDCGEDNI CVPDLQLEVF 660
GEQNHVYLβD KNALNLTFHA QNVGEGGAYE AELRVTAPPE AEYSGLVRHP GNFSSLSCDY 720
FAVNQSRLLV CDLGNPMKAβ ASLWGGLRFT VPHLRDTKKT IQFDFQILSK NLNNSQSDW 780
SFRLSVEAQA QVTLNGVSKP EAVLFPVSDW HPRDQPQKEE DLβPAVHHVY E INQGPSSI 840
SQβVLELSCP QALEGQQLLY VTRVTGLNCT TNHPINPKGL ELDPEβSLHH QQKREAPSRS 900
SASSGPQILK CPEAECFRLR CELGPLHQQE SQSLQLHFRV WAKTFLQREH QPFSLQCEAV 960
YKALKMPYRI LPRQLPQKER QVATAVQWTK AEGSYGVPLW IIILAILFGL LLLGLLIYIL 1020
YKLGFFKRSL PYGTAMEKAQ LKPPATSDA
A9 DNA SEQUENCE Gene name: Integrin, beta 1 (fibronectin receptor, beta, antigen CD29 includes MDF2, MSK12) Unigene number: Hs.287797 Probeset Accession #: X07979 Nucleic Acid Accession tt: NM_002211.1 Coding sequence: 1-2397 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
ATGAATTTAC AACCAATTTT CTGGATTGGA CTGATCAβTT CAGTTTGCTG TGTβTTTGCT 60 CAAACAGATG AAAATAGATG TTTAAAAGCA AATGCCAAAT CATβTGGAGA ATGTATACAA 120 GCAGGGCCAA ATTGTGGGTG GTGCACAAAT TCAACATTTT TACAβGAAGG AATGCCTACT 180 TCTGCACGAT GTGATGATTT AGAAGCCTTA AAAAAGAAGG GTTGCCCTCC AGATGACATA 240 GAAAATCCCA GAGGCTCCAA AGATATAAAG AAAAATAAAA ATGTAACCAA CCGTAGCAAA 300 GGAACAGCAG AGAAGCTCAA GCCAGAGβAT ATTACTCAGA TCCAACCACA GCAGTTGGTT 360 TTGCGATTAA GATCAββββA βCCACAGACA TTTACATTAA AATTCAAGAG AGCTGAAGAC 420 TATCCCATTG ACCTCTACTA CCTTATGGAC CTGTCTTACT CAATβAAAGA CGATTTβGAG 480 AATGTAAAAA GTCTTGGAAC AGATCTGATG AATGAAATGA GGAGGATTAC TTCββACTTC 540 AGAATTGGAT TTGGCTCATT TGTGGAAAAβ ACTGTGATGC CTTACATTAG CACAACACCA 600 GCTAAGCTCA GGAACCCTTG CACAAGTβAA CAGAACTGCA CCAGCCCATT TAGCTACAAA 660 AATβTGCTCA GTCTTACTAA TAAAGGAGAA GTATTTAATG AACTTGTTGG AAAACAGCGC 720 ATATCTGGAA ATTTGβATTC TCCAGAAGGT GGTTTCGATG CCATCATGCA AGTTGCAβTT 780 TGTGGATCAC TGATTGβCTβ GAGGAATGTT ACACGGCTGC TGGTβTTTTC CACAGATGCC 840 GGGTTTCACT TTGCTGβAβA TGGGAAACTT GGTGGCATTG TTTTACCAAA TβATββACAA 900 TGTCACCTGβ AAAATAATAT GTACACAATG AGCCATTATT ATGATTATCC TTCTATTGCT 960 CACCTTGTCC AGAAACTGAG TGAAAATAAT ATTCAGACAA TTTTTGCAGT TACTGAAGAA 1020 TTTCAGCCTG TTTACAAGβA GCTGAAAAAC TTGATCCCTA AGTCAGCAGT AGGAACATTA 1080 TCTGCAAATT CTAGCAATGT AATTCAGTTG ATCATTGATG CATACAATTC CCTTTCCTCA 1140 GAAGTCATTT TGGAAAACGG CAAATTGTCA GAAGGAGTAA CAATAAGTTA CAAATCTTAC 1200 TCCAAβAACG GGGTGAATGG AACAGGGGAA AATGGAAGAA AATGTTCCAA TATTTCCATT 1260 GGAGATβAGG TTCAATTTGA AATTAGCATA ACTTCAAATA AGTGTCCAAA AAAGβATTCT 1320 GACAGCTTTA AAATTAβGCC TCTGGGCTTT ACGGAGGAAG TAGAGGTTAT TCTTCAβTAC 1380 ATCTGTGAAT GTGAATGCCA AAGCGAAGGC ATCCCTGAAA GTCCCAAGTG TCATβAAβGA 1440 AATGGGACAT TTGAβTβTββ CGCGTGCAGG TGCAATGAAG GGCGTGTTGG TAGACATTβT 1500 GAATGCAGCA CAβATGAAGT TAACAGTGAA GACATGGATG CTTACTGCAG GAAAGAAAAC 1560 AGTTCAGAAA TCTGCAGTAA CAATGGAGAG TGCGTCTGCG GACAGTGTGT TTGTAGGAAG 1620 AGββATAATA CAAATGAAAT TTATTCTGGC AAATTCTGCβ AGTGTGATAA TTTCAACTGT 1680 GATAβATCCA ATGGCTTAAT TTβTββAGGA AATGGTGTTT βCAAGTGTCβ TGTβTGTGAG 1740 TGCAACCCCA ACTACACTGG CAGTGCATGT βACTβTTCTT TGGATACTAG TACTTGTGAA 1800 GCCAGCAACG GACAGATCTβ CAATCβCCGG ββCATCTβCβ AGTGTGGTGT CTGTAAGTGT 1860 ACAGATCCGA AGTTTCAAββ βCAAACβTβT GAGATGTGTC AGACCTGCCT TββTβTCTβT 1920 GCTGAGCATA AAGAATβTGT TCAGTGCAGA GCCTTCAATA AAβGAGAAAA GAAAGACACA 1980 TGCACACAGG AATGTTCCTA TTTTAACATT ACCAAGGTAG AAAGTCGGGA CAAATTACCC 2040 CAGCCCβTCC AACCTGATCC TGTβTCCCAT TGTAAGGAβA AGGATGTTGA CGACTGTTGG 2100 TTCTATTTTA CGTATTCAGT GAATGββAAC AACGAGGTCA TGGTTCATGT TGTβGAGAAT 2160 CCAβAGTGTC CCACTGGTCC AGACATCATT CCAATTGTAG CTββTβTGGT TGCTββAATT 2220 GTTCTTATTβ CCCTTGCATT ACTGCTGATA TGGAAGCTTT TAATGATAAT TCATGACAGA 2280 AGGGAGTTTβ CTAAATTTGA AAAGGAGAAA ATGAATGCCA AATGGGACAC GGGTGAAAAT 2340 CCTATTTATA AGAGTGCCGT AACAACTGTG GTCAATCCGA AGTATGAGββ AAAATGA
AIO Protein sequence : Gene name: Integrin, beta 1 (fibronectin receptor, beta, antigen CD29 includes MDF2, MSK12) Unigene number: Hs.287797 Probeset Accession If: X07979 Protein Accession #: NP_002202.1 Signal sequence: 1-21 Transmembrane domains: 732-754 INB domain: 34-464 PSI domain: 26-76 Cellular Localization: plasma membrane
1 11 21 31 41 51 1 1 1 1 I
1 I i 1
MNLQPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCTN STFLQEGMPT 60
SARCDDLEAL KKKGCPPDDI ENPRGSKDIK KNKNVTNRSK GTAEKLKPED ITQIQPQQLV 120
LRLRSGEPQT FTLKFKRAED YPIDLYYLMD LΞYSMKDDLE NVKSLGTDLM NEMRRITSDF 180
RIGFGSFVEK TVMPYISTTP AKLRNPCTSE QNCTSPFSYK NVLSLTNKGE VFNELVGKQR 240
ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ 300
CHLENNMYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL 360
SANSSNVIQL IIDAYNSLSS EVILENGKLS EGVTISYKSY CKNGVNGTGE NβRKCSNISI 420
GDEVQFEISI TSNKCPKKDS DSFKIRPLGF TEEVEVILQY ICECECQSEG IPESPKCHEG 480
NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK 540
RDNTNEIYSG KFCECDNFNC DRSNβLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTSTCE 600
ASNGQICNGR GICECβVCKC TDPKFQGQTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDT 660
CTQECSYFNI TKVESRDKLP QPVQPDPVSH CKEKDVDDCW FYFTYSVNGN NEVMVHWEN 720
PECPTGPDII PIVAβWAGI VLIβLALLLI WKLLMIIHDR REFAKFEKEK MNAKWDTGEN 780
PIYKSAVTTV VNPKYEGK
All DNA SEQUENCE
Gene name: selectin E (endothelial adhesion molecule 1)
Unigene number: Hs.89546
Probeset Accession #: M24736
Nucleic Acid Accession #: NM_000450
Coding sequence: -1833 (underlined sequences correspond to start and stop codons)
21 31 51
ATGATTGCTT CACAGTTTCT CTCAGCTCTC ACTTTGGTβC TTCTCATTAA AGAGAGTGGA 60
GCCTGGTCTT ACAACACCTC CACGGAAGCT ATGACTTATG ATGAGGCCAG TβCTTATTGT 120
CAGCAAAGGT ACACACACCT GGTTGCAATT CAAAACAAAG AAGAGATTGA GTACCTAAAC 180
TCCATATTGA βCTATTCACC AAGTTATTAC TGGATTGGAA TCAGAAAAGT CAACAATGTG 240
TGGGTCTβGG TAGβAACCCA GAAACCTCTG ACAβAAβAAG CCAAGAACTG ββCTCCAGGT 300
GAACCCAACA ATAGGCAAAA AGATGAGGAC TGCGTGGAGA TCTACATCAA GAGAGAAAAA 360
GATβTβββCA TGTGGAATGA TGAGAGGTβC AβCAAβAAGA AGCTTGCCCT ATGCTACACA 420
GCTGCCTGTA CCAATACATC CTGCAGTGGC CACGGTGAAT GTGTAGAGAC CATCAATAAT 480
TACACTTGCA AGTGTGACCC TGGCTTCAβT GGACTCAAGT GTGAβCAAAT TGTGAACTGT 540
ACAGCCCTGG AATCCCCTGA GCATGGAAGC CTGβTTTβCA GTCACCCACT βββAAACTTC 600
AGCTACAATT CTTCCTGCTC TATCAGCTβT GATAGGGGTT ACCTGCCAAG CAGCATGGAG 660
ACCATGCAGT GTATGTCCTC TGGAGAATβG AGTGCTCCTA TTCCAGCCTG CAATGTGGTT 720
GAGTGTGATG CTGTGACAAA TCCAGCCAAT GGGTTCGTGG AATGTTTCCA AAACCCTGGA 780
AGCTTCCCAT GGAACACAAC CTβTACATTT GACTGTGAAG AAGGATTTGA ACTAATβGGA 840
GCCCAGAGCC TTCAGTGTAC CTCATCTGGG AATTGGβACA ACGAGAAGCC AACGTGTAAA 900
GCTGTβACAT GCAGGβCCβT CCGCCAGCCT CAβAATGβCT CTGTβAGGTG CAGCCATTCC 960
CCTGCTββAG AβTTCACCTT CAAATCATCC TβCAACTTCA CCTGTGAGGA AGGCTTCATG 1020
TTGCAGGGAC CAGCCCAGGT TβAATβCACC ACTCAAGGGC AGTGGACACA GCAAATCCCA 1080
GTTTβTβAAG CTTTCCAGTG CACAGCCTTG TCCAACCCCG AGCGAGGCTA CATGAATTGT 1140
CTTCCTAGTG CTTCTGGCAG TTTCCGTTAT GGGTCCAGCT GTGAGTTCTC CTGTGAGCAβ 1200
GGTTTTGTβT TGAAGGGATC CAAAAGβCTC CAATGTGGCC CCACAGGGGA GTGGGACAAC 1260
GAGAAGCCCA CATGTGAAGC TβTGAGATGC GATGCTGTCC ACCAGCCCCC GAAβGGTTTG 1320
GTβAββTGTG CTCATTCCCC TATTGβAβAA TTCACCTACA AGTCCTCTTG TGCCTTCAGC 1380
TGTGAββAGG GATTTGAATT ATATGGATCA ACTCAACTTG AGTGCACATC TCAGGGACAA 1440
TGGACAGAAG AGGTTCCTTC CTGCCAAβTG GTAAAATGTT CAAGCCTββC AGTTCCGGGA 1500
AAGATCAACA TGAGCTGCAG TGGGGAGCCC GTGTTTGGCA CTGTβTGCAA GTTCGCCTGT 1560
CCTGAAGGAT GGACGCTCAA TββCTCTβCA GCTCGGACAT GTGGAGCCAC AGβACACTGG 1620
TCTGGCCTGC TACCTACCTG TGAAGCTCCC ACTGAGTCCA ACATTCCCTT GGTAGCTGGA 1680
CTTTCTGCTG CTββACTCTC CCTCCTβACA TTAGCACCAT TTCTCCTCTG GCTTCGGAAA 1740
TGCTTACββA AAGCAAAGAA ATTTGTTCCT GCCAGCAGCT GCCAAAGCCT TGAATCAGAC 1800
GGAAGCTACC AAAAGCCTTC TTACATCCTT TAA
A12 Protein sequence:
Gene name : Selectin E (endothelial adhesion molecule 1)
Unigene number: Hs.89546
Probeset Accession #: M24736
Protein Accession # : NP_000441
Signal sequence: 1-22
Transmembrane domains : 555-573
C-lectin domain: 23-139 Cellular Localization: plasma membrane
1 11 21 31 41 51
I I I I I I
MIASQFLSAL TLVLLIKESG AWSYNTSTEA MTYDEASAYC QQRYTHLVAI QNKEEIEYLN 60
SILSYSPSYY WIGIRKVNNV WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK 120
DVGMWNDERC SKKKLALCYT AACTNTSCSG HGECVETINN YTCKCDPGFS GLKCEQIVNC 180
TALESPEHβS LVCSHPLGNF SYNSSCSISC DRGYLPSSME TMQCMSSGEW SAPIPACNW 240 0 ECDAVTNPAN GFVECFQNPG SFPWNTTCTF DCEEGFELMG AQSLQCTSSG NWDNEKPTCK 300
AVTCRAVRQP QNGSVRCSHS PAGEFTFKSS CNFTCEEGFM LQGPAQVECT TQβQWTQQIP 360
VCEAFQCTAL SNPERβYMNC LPSASCSFRY GSSCEFSCEQ GFVLKGSKRL QCGPTGEWDN 420
EKPTCEAVRC DAVHQPPKGL VRCAHSPIGE FTYKSSCAFS CEEGFELYGS TQLECTSQGQ 480
WTEEVPSCQV VKCSSLAVPG KINMSCΞGEP VFGTVCKFAC PEGWTLNGSA ARTCGATGHW 540 5 SβLLPTCEAP TESNIPLVAG LSAAGLSLLT LAPFLLWLRK CLRKAKKFVP ASSCQSLESD 600 GSYQKPSYIL
A13 DNA SEQUENCE Gene name: G protein-coupled receptor 39 0 Unigene number: Hs .85339 Probeset Accession #: AA349893 Nucleic Acid Accession #: NM_001508 Coding sequence: 1-1362 (underlined sequences correspond to start and stop codons) 5 1 11 21 31 41 51
I I I I I I
ATGGCTTCAC CCAGCCTCCC GGGCAGTGAC TGCTCCCAAA TCATTGATCA CAGTCATGTC 60
CCCGAGTTTG AGGTGGCCAC CTGGATCAAA ATCACCCTTA TTCTGGTGTA CCTGATCATC 120
TTCGTGATGG GCCTTCTGGG GAACAGCGCC ACCATTCGGβ TCACCCAGβT GCTGCAGAAG 180 0 AAAββATACT TGCAGAAGGA GβTGACAGAC CACATβGTGA GTTTGGCTTG CTCGGACATC 240
TTGGTGTTCC TCATCGGCAT GCCCATGβAβ TTCTACAGCA TCATCTGGAA TCCCCTGACC 300
ACGTCCAGCT ACACCCTGTC CTGCAAGCTG CACACTTTCC TCTTCGAGGC CTGCAGCTAC 360
GCTACGCTGC TGCACGTGCT GACACTCAGC TTTGAGCGCT ACATCGCCAT CTGTCACCCC 420
TTCAGGTACA AGGCTGTGTC GGGACCTTGC CAGGTGAAGC TGCTGATTGG CTTCβTCTGG 480 5 GTCACCTCCG CCCTββTGGC ACTGCCCTTG CTGTTTGCCA TGGGTACTGA GTACCCCCTG 540
GTGAACGTβC CCAGCCACCG GGGTCTCACT TGCAACCGCT CCAGCACCCG CCACCACGAG 600
CAGCCCGAGA CCTCCAATAT GTCCATCTGT ACCAACCTCT CCAGCCGCTG GACCGTβTTC 660
CAGTCCAGCA TCTTCββCCC CTTCβTGGTC TACCTCGTGβ TCCTGCTCTC CGTAGCCTTC 720
ATGTGCTGGA ACATGATGCA GβTGCTCATβ AAAAGCCAGA AGGGCTCGCT GGCCGGGGGC 780 0 ACGCGGCCTC CGCAGCTGAG GAAGTCCGAβ AGCGAAGAβA GCAGGACCGC CAGβAGGCAG 840
ACCATCATCT TCCTGAGGCT GATTGTTGTG ACATTGGCCG TATGCTGGAT GCCCAACCAβ 900
ATTCβGAGGA TCATGGCTGC GGCCAAACCC AAGCACGACT GGACGAβGTC CTACTTCCGG 960 βCGTACATGA TCCTCCTCCC CTTCTCGGAG ACGTTTTTCT ACCTCAGCTC GGTCATCAAC 1020
CCGCTCCTGT ACACGGTGTC CTCGCAGCAG TTTCGGCGGβ TGTTCGTGCA GGTβCTGTGC 1080
45 TβCCβCCTGT CβCTGCAGCA CGCCAACCAC GAGAAGCGCC TGCGCGTACA TGCGCACTCC 1140
ACCACCGACA GCGCCCGCTT TGTGCAGCGC CCGTTGCTCT TCGCGTCCCG GCGCCAGTCC 1200
TCTGCAAGβA βAACTGAGAA GATTTTCTTA AGCACTTTTC AGAGCβAGGC CGAGCCCCAβ 1260
TCTAAGTCCC AGTCATTGAG TCTCGAGTCA CTAGAGCCCA ACTCAGGCGC GAAACCAGCC 1320 AATTCTGCTG CAGAGAATGG TTTTCAββAG CATGAAβTTT GA
50
A14 Protein sequence:
Gene name: G protein-coupled receptor 39
Unigene number: Hs.85339 _•_> Probeset Accession #-. AA349893
Protein Accession # : NM_001508, NP_001409
Signal sequence: none found
Pfam domains: 7tm_l [72-172, 224-344]
Transmembrane domains: 32-54, 68-90, 111-133, 151-173, 221-243 , 280-301 , 320-342 60 Cellular Localization: plasma membrane
1 11 21 31 41 51
„ I I I I I I
OJ MASPSLPGSD CSQIIDHSHV PEFEVATWIK ITLILVYLII FVMGLLGNSA TIRVTQVLQK 60
KGYLQKEVTD HMVSLACSDI LVFLIGMPME FYSIIWNPLT TSSYTLSCKL HTFLFEACSY 120
ATLLHVLTLS FERYIAICHP FRYKAVSGPC QVKLLIGFVW VTSALVALPL LFAMGTEYPL 180
VNVPSHRGLT CNRSSTRHHE QPETSNMSIC TNLSSRWTVF QSSIFGAFW YLWLLSVAF 240
MCWNMMQVLM KSQKGSLAGG TRPPQLRKSE SEESRTARRQ TIIFLRLIW TLAVCWMPNQ 300
70 IRRIMAAAKP KHDWTRSYFR AYMILLPFSE TFFYLSSVIN PLLYTVSSQQ FRRVFVQVLC 360
CRLSLQHANH EKRLRVHAHS TTDSARFVQR PLLFASRRQS SARRTEKIFL STFQSEAEPQ 420 SKSQSLSLES LEPNSβAKPA NSAAENGFQE HEV
75 AI Prostate
A15 DNA sequence Gene name: CEGP1 Unigene number: HS.222399 Ovj Probeset Accession #: AA256485
Nucleic Acid Accession ft: AJ400877 Coding sequence : 81-3080 (underlined sequences correspond to start and stop codons)
11 21 31 41 51 I I I I I I
GGCGTCCGCG CACACCTCCC CGCGCCGCCG CCGCCACCβC CCβCACTCCG CCGCCTCTGC 60
CCGCAACCGC TCAGCCATCC ATGGGββTCG CGGGCCGCAA CCGTCCCGGG GCGGCCTGGG 120
CGGTGCTβCT GCTGCTGCTG CTGCTGCCGC CACTGCTGCT GCTGGCGGGG GCCGTCCCβC 180
CGGGTCGGGG CCβTGCCGCβ GGGCCGCAGβ AGGATGTAGA TGAGTGTGCC CAAGGGCTAG 240
ATGACTGCCA TGCCGACGCC CTGTGTCAGA ACACACCCAC CTCCTACAAG TGCTCCT6CA 300
AGCCTGGCTA CCAAGβββAA GGCAβGCAGT GTGAGGACAT CGATGAATGT ββAAATβAGC 360
TCAATGGAGG CTβTβTCCAT GACTGTTTGA ATATTCCAGG CAATTATCGT TGCACTTGTT 420
TTGATGGCTT CATβTTββCT CATCACGGTC ATAATTGTCT TGATGTGGAC GAGTGCCTββ 480
AGAACAATGβ CCGCTGCCAβ CATACCTGTG TCAACGTCAT GGGGAGCTAT GAGTβCTGCT 540
GCAAGβAβββ βTTTTTCCTG AGTGACAATC AGCACACCTβ CATTCACCGC TCGβAAGAGG 600
GCCTGAGCTG CATβAATAAβ GATCACGGCT βTAβTCACAT CTβCAAGGAG GCCCCAAGGG 660 βCAGCGTCGC CTGTβAβTβC AGGCCTGβTT TTGAGCTGβC CAAβAACCAβ AGAGACTGCA 720
TCTTGACCTβ TAACCATGββ AACGGTGββT GCCAGCACTC CTGTGACGAT ACAGCCGATG 780
GCCCAGAβTβ CAβCTβCCAT CCACAβTACA AGATGCACAC AGATGGGAGG AGCTGCCTTG 840
AGCGAGAGGA CACTGTCCTG GA6GTGACAG AGAGCAACAC CACATCAGTG GTGGATGβGG 900
ATAAACCββT βAAACGGCββ CTβCTCATCβ AAACGTGTGC TGTCAACAAT GGAGGCTβTβ 960
ACCβCACCTβ TAAGGATACT TCGACAββTβ TCCACTβCAβ TTGTCCTGTT GGATTCACTC 1020
TCCAGTTGGA TGGGAAGACA TGTAAAGATA TTGATGAGTβ CCAGACCCGC AATGGAGGTT 1080 βTGATCATTT CTGCAAAAAC ATCGTGβGCA βTTTTGACTG CGGCTβCAAG AAAGGATTTA 1140
AATTATTAAC AGATβAβAAβ TCTTGCCAAG ATGTGGATβA βTGCTCTTTG GATAGGACCT 1200
GTGACCACAβ CTβCATCAAC CACCCTββCA CATTTGCTTβ TGCTTGCAAC CGAGGGTACA 1260
CCCTGTATGG CTTCACCCAC TGTGGAGACA CCAATGAGTG CAGCATCAAC AACGGAGβCT 1320 βTCAβCAβGT CTGTGTGAAC ACAGTGGGCA GCTATGAATG CCAGTGCCAC CCTGGβTACA 1380
AGCTCCACTG GAATAAAAAA GACTGTGTGG AAGTGAAGGG GCTCCTGCCC ACAAGTGTβT 1440
CACCCCGTGT GTCCCTGCAC TGCGGTAAGA GTGGTGGAGG AGACGGGTGC TTCCTCAGAT 1500
GTCACTCTGβ CATTCACCTC TCTTCAβATG TCACCACCAT CAGβACAAβT βTAACCTTTA 1560
AGCTAAATβA AββCAAGTGT AGTTTGAAAA ATGCTβAGCT GTTTCCCGAG GGTCTGCGAC 1620
CAGCACTACC AGAGAAβCAC AGCTCAGTAA AAGAβAβCTT CCβCTACGTA AACCTTACAT 1680
GCAGCTCTββ CAAβCAAβTC CCAGGAGCCC CTGGCCGACC AAGCACCCCT AAββAAATGT 1740
TTATCACTGT TGAGTTTGAG CTTGAAACTA ACCAAAAGGA GGTGACAGCT TCTTGTGACC 1800
TGAGCTGCAT CGTAAAGCβA ACCGAGAAGC GGCTCCGTAA AGCCATCCGC ACGCTCAGAA 1860
AββCCCTCCA CAGGβAβCAβ TTTCACCTCC AβCTCTCAGG CATβAACCTC GACGTGGCTA 1920
AAAAβCCTCC CACAACATCT CAACβCCACβ CAβAGTCCTG TGGAGTGGGC CAGGGTCATG 1980
CAGAAAACCA ATβTβTCAβT TGCACβGCTG GGACCTATTA TGATββAGCA CGAGAACGCT 2040
GCATTTTATβ TCCAAATGGA ACCTTCCAAA ATGAβGAAβG ACAAATGACT TGTGAACCAT 2100
GCCCAAβACC AββAAATTCT GββGCCCTGA AβACCCCAβA AβCTTGGAAT ATGTCTGAAT 2160
GTGGAGβTCT βTβTCAACCT GGTGAATATT CTGCAGATββ CTTTGCACCT TGCCAGCTCT 2220
GTβCCCTGββ CACβTTCCAβ CCTGAAGCTβ βTCGAACTTC CTGCTTCCCC TGTGGAGGAG 2280
GCCTTGCCAC CAAACATCAG ββAGCTACTT CCTTTCAGGA CTβTβAAACC AGAGTTCAAT 2340
GTTCACCTββ ACATTTCTAC AACACCACCA CTCACCβATβ TATTCβTTGC CCAGTGGGAA 2400
CATACCAGCC TGAATTTGGA AAAAATAATT βTβTTTCTTG CCCAGβAAAT ACTACGACTG 2460
ACTTTGATGG CTCCACAAAC ATAACCCAGT GTAAAAACAG AAGATGTGGA GGGGAGCTGG 2520
GAGATTTCAC TGββTACATT GAATCCCCAA ACTACCCAGβ CAATTACCCA GCCAACACCG 2580
AGTGTACGTG GACCATCAAC CCACCCCCCA AGCGCCGCAT CCTGATCGTG GTCCCTGAβA 2640
TCTTCCTGCC CATAGAGGAC GACTGTGGGG ACTATCTGGT GATGCGGAAA ACCTCTTCAT 2700
CCAATTCTGT GACAACATAT GAAACCTGCC AGACCTACGA ACGCCCCATC GCCTTCACCT 2760
CCAGGTCAAA GAAGCTGTGG ATTCAGTTCA AGTCCAATGA AGGGAACAβC GCTAGAGGGT 2820
TCCAGGTCCC ATACGTGACA TATGATGAGG ACTACCAGGA ACTCATTGAA GACATAβTTC 2880 βAβATβGCAG βCTCTATGCA TCTGAGAACC ATCAGGAAAT ACTTAAGGAT AAβAAACTTA 2940
TCAACβCTCT GTTTGATβTC CTGGCCCATC CCCAGAACTA TTTCAAβTAC ACAGCCCAGG 3000
AGTCCCGAGA GATGTTTCCA AβATCβTTCA TCCGATTGCT ACGTTCCAAA GTGTCCAGGT 3060
TTTTGAGACC TTACAAATGA CTCAGCCCAC βTβCCACTCA ATACAAATGT TCTGCTATAG 3120
GGTTGGTGGG ACAGAGCTGT CTTCCTTCTG CATGTCAGCA CAGTCGGGTA TTGCTGCCTC 3180
CCGTATCAGT GACTCATTAG AGTTCAATTT TTATAGATAA TACAGATATT TTGGTAAATT 3240
GAACTTGGTT TTTCTTTCCC AGCATCGTGG ATGTAGACTG AGAATGGCTT TGAGTGGCAT 3300
CAGCTTCTCA CTGCTGTGGG CGGATGTCTT GGATAβATCA CGGβCTβGCT GAGCTGGACT 3360
TTGGTCAGCC TAGGTGAGAC TCACCTGTCC TTCTGGGGTC TTACTCCTCC TCAAGGAβTC 3420
TGTAGTGGAA AGβAβGCCAC AGAATAAGCT GCTTATTCTβ AAACTTCAGC TTCCTCTAGC 3480
CCGGCCCTCT CTAAGββAβC CCTCTGCACT CGTβTGCAGG CTCTGACCAG GCAGAACAGG 3540
CAAGAGGββA βGGAAGGAGA CCCCTGCAββ CTCCCTCCAC CCACCTTβAβ ACCTGG6AGG 3600
ACTCAGTTTC TCCACAGCCT TCTCCAGCCT βTβTβATACA AβTTTGATCC CAGGAACTTG 3660
AGTTCTAAGC AGTGCTCGTG AAAAAAAAAA GCAβAAAβAA TTAβAAATAA ATAAAAACTA 3720 AGCACTTCTG GAGACAT
A16 Protein sequence Gene name: CEGP1 Unigene number: Hs.222399 Probeset Accession #: AA256485 Protein Accession #: CAB92285 Signal sequence: 1-31 Transmembrane domains : none PFAM domains : EGF-like_domains [49-84,132-167,177-213,286-321,407-442]
CUB_domain [809-918]
Cellular Localization: may be secreted
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MGVAGRNRPG AAWAVLLLLL LLPPLLLLAG AVPPGRGRAA GPQEDVDECA QGLDDCHADA 60 LCQNTPTSYK CSCKPGYQGE βRQCEDIDEC GNELNGGCVH DCLNIPGNYR CTCFDGFMLA 120 HDGHNCLDVD ECLENNββCQ HTCVNVMβSY ECCCKEGFFL SDNQHTCIHR SEEGLSCMNK 180 DHGCSHICKE APRGSVACEC RPGFELAKNQ RDCILTCNHG NGGCQHSCDD TADGPECSCH 240 PQYKMHTDGR SCLEREDTVL EVTESNTTSV VDGDKRVKRR LLMETCAVNN GGCDRTCKDT 300 STGVHCSCPV GFTLQLDGKT CKDIDECQTR NGGCDHFCKN IVGSFDCβCK KGFKLLTDEK 360
SCQDVDECSL DRTCDHSCIN HPGTFACACN RGYTLYGFTH CGDTNECSIN NGGCQQVCVN 420
TVGSYECQCH PGYKLHWNKK DCVEVKβLLP TSVSPRVSLH CGKSβββDGC FLRCHSGIHL 480
SSDVTTIRTS VTFKLNEGKC SLKNAELFPE GLRPALPEKH SSVKESFRYV NLTCSSGKQV 540
PGAPGRPSTP KEMFITVEFE LETNQKEVTA SCDLSCIVKR TEKRLRKAIR TLRKAVHREQ 600
FHLQLSGMNL DVAKKPPRTS ERQAESCβVG QGHAENQCVS CRAGTYYDGA RERCILCPNG 660
TFQNEEGQMT CEPCPRPGNS GALKTPEAWN MSECGβLCQP GEYSADGFAP CQLCALβTFQ 720
PEAGRTSCFP CGGGLATKHQ GATSFQDCET RVQCSPGHFY NTTTHRCIRC PVGTYQPEFG 780
KNNCVSCPGN TTTDFDGSTN ITQCKNRRCG GELGDFTGYI ESPNYPGNYP ANTECTWTIN 840
PPPKRRILIV VPEIFLPIED DCGDYLVMRK TSSSNSVTTY ETCQTYERPI AFTSRSKKLW 900
IQFKSNEβNS ARGFQVPYVT YDEDYQELIE DIVRDGRLYA SENHQEILKD KKLIKALFDV 960 LAHPQNYFKY TAQESREMFP RSFIRLLRSK VSRFLRPYK
A17 DNA sequence
Gene name: ESTs
Unigene number: Hs.293102
Probeset Accession #: AI951118, AW170035, AL044891, AI908272
Nucleic Acid Accession # : none found
Coding sequence: 1-489 (entire sequence is an open-reading-frame)
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C IAAAAAGAAA TIAGATAAAAT AIAATGGAAAA TITAGAAGAβT CITCCTβATAA TIGATGGTTTT 60
CTGAAGGCTC CCTGCAGAAT GAAAGTTTCT ATTCCAACTA AAGCCTTAGA ATTGATGGAC 120
ATGCAAACTT TCAAAGCAGA GCCTCCCGAG AAGCCATCTG CCTTCGAGCC TGCCATTGAA 180
ATGCAAAAGT CTGTTCCAAA TAAAGCCTTG GAATTGAAGA ATGAACAAAC ATTGAGAGCA 240
GATCAGATGT TCCCTTCAGA ATCAAAACAA AAGAAS6TTG AAGAAAATTC TTβGGATTCT 300
GAGAGTCTCC GTGAβACTGT TTCACAGAAG GATGTGTβTG TACCCAAGGC TACACATCAA 360
AAAGAAATGG ATAAAATAAG TGβAAAATTA βAAGATTCAA CTAGCCTATC AAAAATCTTG 420
GATACAGTTC ATTCTTGTGA AAGAACAAββ GAACTTCAAA AAGACCCCTG TGACCCACGT 480 TCAGGAAAA
AI8 Protein sequence
Gene name: ESTs
Unigene number: Hs.293102
Probeset Accession ft: AI951118, AW170035, AL044891, AI908272
Protein Accession #: none found
Signal sequence: none
Transmembrane domains : none
Cellular Localization: nuclear
1 ' 11 21 31 41 51
I I I I I I
QKEIDKINGK LEESPDNDGF LKAPCRMKVS IPTKALELMD MQTFKAEPPE KPSAFEPAIE 60
MQKSVPNKAL ELKNEQTLRA DQMFPSESKQ KXVEENSWDS ESLRETVSQK DVCVPKATHQ 120 KEMDKISβKL EDSTSLSKIL DTVHSCERTR ELQKDPCDPR SGK
Breas '
A19 DNA SEQUENCE
Gene name: TMPRSS3a
Unigene number: Hs.298241
Probeset Accession ft: AI538613
Nucleic Acid Accession #: AB038157
Coding sequence: 202-1566 (underlined sequences correspond to start and stop codons)
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I I I I I I
ACCGGGCACC GβACGGCTCG GGTACTTTCβ TTCTTAATTA βGTCATβCCC GTGTGAGCCA 60
GGAAAGGGCT GTGTTTATGG GAAGCCAGTA ACACTGTGGC CTACTATCTC TTCCGTGGTG 120
CCATCTACAT TTTT6GGACT CGGGAATTAT GAGGTAGAGG TGGAGGCGGA GCCGGATGTC 180
AGAGβTCCTG AAATAGTCAC CATGββββAA AATGATCCGC CTGCTβTTGA AGCCCCCTTC 240
TCATTCCGAT CGCTTTTTGG CCTTβATβAT TTβAAAATAA βTCCTβTTGC ACCAGATGCA 300
GATGCTβTTG CTGCACAGAT CCTGTCACTG CTGCCATTGA AGTTTTTTCC AATCATCGTC 360
ATTGGGATCA TTGCATTGAT ATTAGCACTG GCCATTGβTC TGGGCATCCA CTTCGACTGC 420
TCAGGGAAGT ACAGATGTCG CTCATCCTTT AAGTGTATCG AGCTGATAGC TCGATGTGAC 480
GGAGTCTCGG ATTGCAAAGA CGGGGAGGAC GAGTACCGCT GTGTCCβGGT GGβTGGTCAG 540
AATGCCβTGC TCCAGGTGTT CACAGCTGCT TCGTGGAAGA CCATGTβCTC CGATGACTGG 600
AAGGGTCACT ACGCAAATGT TGCCTGTGCC CAACTGββTT TCCCAAGCTA TGTGAGTTCA 660
GATAACCTCA GAGTGAGCTC GCTGGAGβGG CAGTTCCGGG AGGAGTTTβT GTCCATCGAT 720
CACCTCTTGC CAGATGACAA G6TGACTGCA TTACACCACT CAGTATATGT GAGGβAβGGA 780
TGTGCCTCTG GCCACGTGGT TACCTTGCAG TGCACAGCCT GTGGTCATAG AAGβββCTAC 840
AGCTCACGCA TCGTGGGTGG AAACATGTCC TTGCTCTCGC AGTGGCCCTG GCAβGCCAGC 900
CTTCA6TTCC AβGGCTACCA CCTGTGCGββ GGCTCTGTCA TCACGCCCCT GTGβATCATC 960
ACTβCTβCAC ACTGTGTTTA TGACTTGTAC CTCCCCAAGT CATββACCAT CCAβGTGGGT 1020
CTAGTTTCCC TβTTGGACAA TCCAGCCCCA TCCCACTTGG TGGAGAAGAT TβTCTACCAC 1080
AGCAAGTACA AGCCAAAGAG GCTβGGCAAT GACATCGCCC TTATGAAGCT GGCCGGGCCA 1140
CTCACGTTCA ATβAAATGAT CCAGCCTGTG TGCCTGCCCA ACTCTGAAGA GAACTTCCCC 1200
GATGGAAAAG TβTβCTGβAC GTCAβGATGG GGGGCCAGAG AGGATGGAGC AGGTGACGCC 1260
TCCCCTGTCC TGAACCACGC G6CCGTCCCT TTGATTTCCA ACAAGATCTG CAACCACAGG 1320
GACβTβTACβ GTGGCATCAT CTCCCCCTCC ATGCTCTGCβ CGGGCTACCT GACGGGTGGC 1380 GTGGACAGCT GCCAGGGGGA CAGCGGGGGG CCCCTGGTGT GTCAAGAGAG GAGβCTGTGG 1440 AAGTTAGTGG GAGCGACCAG CTTTGGCATC GGCTβCβCAG AGGTGAACAA GCCTGGGGTG 1500 TACACCCGTG TCACCTCCTT CCTGGACTGG ATCCACGAGC AGATGGAGAG AGACCTAAAA 1560 ACCTGAAGAG GAAGGGGACA AGTAGCCACC TGAGTTCCTG AGGTGATGAA βACAGCCCGA 1620 TCCTCCCCTG GACTCCCGTG TAGβAACCTG CACACGAGCA GACACCCTTG GAGCTCTβAG 1680 TTCCGβCACC AGTAGCAGGC CCGAAAβAβG CACCCTTCCA TCTGATTCCA GCACAACCTT 1740 CAAGCTGCTT GTTTTTTTGA GβTGGAGTCT CGCTCTGTTG CCCAGGCTGG 1800 AGTGCAGTGG CGAAATCCCT GCTCACTGCA GCCTCCGCTT CCCTGGTTCA AGCGATTCTC 1860 TTGCCTCAGC TTCCCCAGTA GCTβGGACCA CAGβTβCCCβ CCACCACACC CAACTAATTT 1920
10 TTGTATTTTT AGTAGAGACA GGGTTTCACC ATGTTGβCCA GβCTGCTCTC AAACCCCTGA 1980 CCTCAAATβA TGTGCCTGCT TCAGCCTCCC ACAGTGCTGG GATTACAGGC ATGGGCCACC 2040 ACGCCTAGCC TCACβCTCCT TTCTβATCTT CACTAAGAAC AAAAGAAGCA GCAACTTGCA 2100 AGββCβGCCT TTCCCACTββ TCCATCTβGT TTTCTCTCCA GGGGTCTTGC AAAATTCCTG 2160 ACGAβATAAβ CAGTTATGTβ ACCTCACGTβ CAAAGCCACC AACAGCCACT CAGAAAAGAC 2220
15 βCACCAGCCC AβAAβTβCAC AACTGCAGTC ACTGCACGTT TTCATCTCTA GGGACCAGAA 2280 CCAAACCCAC CCTTTCTACT TCCAAGACTT ATTTTCACAT GTGGGGAGβT TAATCTAGGA 2340 ATGACTCGTT TAAGGCCTAT TTTCATGATT TCTTTGTAGC ATTTGGTGCT TGACGTATTA 2400 TTGTCCTTTG ATTCCAAATA ATATGTTTCC TTCCCTCAAA AAAAAAAAAA AAAAAAAAAA 2460 AAAAAAAA
20
A20 Protein sequence: Gene name: TMPRSS3a Unigene number: Hs.298241
2.D Probeset Accession #: AI538613
Protein Accession #: BAB20077 Signal sequence: none found Transmembrane domains: 43-65, 239-261 Tryp_SPc domain: 216-444
30 Cellular Localization: not determined
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35 MGENDPPAVE A IPFSFRSLFG L IDDLKISPVA P IDADAVAAQI L ISLLPLKFFP I IIVIGIIALI 60 LALAIGLGIH FDCSGKYRCR SSFKCIELIA RCDGVSDCKD GEDEYRCVRV GβQNAVLQVF 120 TAASWKTMCS DDWKGHYANV ACAQLβFPSY VSSDNLRVSS LEGQFREEFV SIDHLLPDDK 180 VTALHHSVYV REGCASGHW TLQCTACβHR RGYSSRIVGG NMSLLSQWPW QASLQFQβYH 240 LCGGSVITPL WIITAAHCVY DLYLPKSWTI QVβLVSLLDN PAPSHLVEKI VYHSKYKPKR 300
40 LGNDIALMKL AGPLTFNEMI QPVCLPNSEE NFPDβKVCWT SGWGATEDGA GDASPVLNHA 360 AVPLISNKIC NHRDVYGβll SPSMLCAβYL TGGVDSCQGD SGGPLVCQER RLWKLVGATS 420 FGIGCAEVNK PβVYTRVTSF LDWIHEQMER DLKT
A21 DNA SEQUENCE
45 Gene name: ESTs; opposite strand to TRPS1 Unigene number: none Probeset Accession #: AA428090 Nucleic Acid Accession #: AA428090
Coding sequence: 1-558 (underlined sequences correspond to start and stop codons)
50
60
120
55
Figure imgf000839_0001
180
GATTCTGTTG GGCTTCCTGG TAGAGCTGGA GACAGACTGC AACCCAAGAC AAAACCCAGA 240
GGAAAAACAA CTAACCTCAG CCATTTGCCC AATTTCCACC TTGCTAGTTA TCAGAGTTCA 300
CTATTGTTTA AGCTCCAGGG GTCATACTAT GGCAATCTAC TGGTGGAATT TATTCTGAβC 360
AAGTGTTTTG TTCAGCTTGC AGTATTAAAA CAAAAAAAAC ATTGCCTCCA GCTGCAAAGC 420
60 AAGGGCATTG CCATTATGAA AβCCCCTCAA AβACTCTCTG CTATTTTCAA AACATGβAAA 480
GAAAAAGGGA AAAAAGAAAA AAAAATAATA ATTAGAAGGA TTTGTTCCTT AATTTGGGCT 540
CCCAAAAATG AGAAATGAAG ATTGTATAAT GAGGβGAGAT ACTAATTATT TTAAACTCTC 600
CAAβCAAATC TTCTGAAβCA ATCAATTATT TATATACTTT ATGTTCTGTC TTTTTGTATT 660
TTTCCTTCTβ βTTAAAAACA TGCAGGTGAG TCTTGCCAAC GTCCTTTCCT ATCTββATCT 720
65 GTTCTGCCTC ATTTCTCTTT CAAAGTCATC TTTCAGGGAA CTTGCCCTGA TTAATTTGAT 780
TTTAACCAAA CAAATAAβAT ATTTGATATA TTAATTTAAA CTTTTTGAGA TGATTβATTA 840
GGAATTGCAT CATβTTCACA TGAGTATACC GAATTCAAAG TTAAACTTCA TAAβCAGGAG 900
TTTTTACACA TCβTAACATA ATCATTACCC AATACTCGAC ACTCAATATT TGATACTCAA 960
CTGAATGTTT TTGAAATAAA CACATTTTTA TGTTATCTCT CTGβAGAAAG TAGTATATAT 1020
70 CTTTTTACAC AAAATATATC AGTGAGAβAG TGTTTβTTTA AGAAAAAAAA TCAAAβCACA 1080
ACAAGTTGAG AGAGTCCAGG CTTTATCAAT ATAAGTAATA ATTTTTTAGA ATGGTGATTT 1140
GATTTCACCA TTTCAATTCA GCAGAGCCTG TATATATATA TATATATATA TATATATATA 1200
TATATATATA TATATATATA TATATTACAA TGATCTGTAT TTCCTATTGC TAGAAGβATβ 1260
AAAGTGAATC CATATAAACC ATACCAACGC CGTTATGTGT AACTGGTGGT AAAACTTTAT 1320
75 TATTCAAGTT TAGATGTAAC AGACATCTTT GCTGCCTGAA GATTGTTTGC ATAAGAAATA 1380
CACCAAGAAC ATGTTTβTGA GTAGAAATGA ACATGCACTA TGAAAACAAA ATAAAATAAA 1440
ACGAAAAAAT TTCATGTβTT GTAAGAACAG AACTATTATA GCCAACATTC TAGTATTCAA 1500
ATCAGGACTA CAAATTβAAT TCTTTTTCTT AGCAACATGA AATCATTCCA TATGAAAGAC 1560
ATTTTCTGCT ββTβAATATT GCTGTAAGTT AAATTTTACA TTGβCATTTT GAGATGTTCC 1620
80 CCCCTCATGC CTCCCCCAAA GTTTTCCATG TGGTTGTCAA ATAGTCCGC
A22 Protein sequence : Gene name : ESTs; opposite strand to TRPS1 Unigene number: none Probeset Accession #: AA428090 Protein Accession #: none found Signal sequence : none found Transmembrane domains: 113-129 Cellular Localization: not determined
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MKPSLKHWAD IKMFSEIDQR QWGEEIHLQ WSVSYLVEN FSDTDDLMSI VEESDSCYNR 60
DSVGLPGRAG DRLQPKTKPR GKTTNLSHLP NFHLASYQSS LLFKLQGSYY GNLLVEFILS 120
KCFVQLAVLK QKKHCLQLQS KGIAIMKAPQ RLSAIFKTWK EKGKKEKKII IRRICSLIWA 180 PKNEK
A23 DNA SEQUENCE Gene name : ESTs Unigene number: Hs .29383
Probeset Accession # : AW207206 Nucleic Acid Accession # : AL133619
Coding sequence : 1-2070 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 1 1 11 11 11 11 11
ATGAGCGGTG CGGGGGTGGC GGCTβGGACG CGGCCCCCCA GCTCGCCGAC CCCGβGCTCT 60
CβGCGCCGGC GCCAGC6CCC CTCTβTGGGC GTCCAGTCCT TGAGβCCGCA GAGCCCβCAβ 120
CTCAGGCAGA GCGACCCGCA GAAACGβAAC CTGGACCTGG AGAAAAGCCT GCAGTTCCTG 180
CAGCAGCAβC ACTCββAβAT GCTGβCCAAG CTCCATGAGG AGATCGAGCA TCTGAAGCGG 240
GAAAACAAβG GTGAGCCGGC GCGβGGCCCT AGβCCGGCCC TGCCTCCCCA GβCACACTCA 300
ACACTGCCGC TCCCGCAGCA CAGAAACACA GCCATCAACT CCAGCACACG CCTββGCTCA 360 βββββAACAC AβGACGGGGA GCCCCTCCAG ACTGTCCTTG CCCACCTGGC TGCACTGGCC 420
CCTGTATGCC AACCCAGTGG GTACAGGTTC TGGGβGACCT GGACACATGC CGCTACCTCT 480
AGCCGTGGCT GβACGATGTT ATGCAβCCAA βCACAGCACG TGCTβCTCTC GGGAAGCCCA 540
GββCCTGAGG TCATTGCAGG GCGGCAGGTG GCCACAGGGT GCTCCCCAGA CCTCCCTCCT 600
CCAAGTAGAG CTGAAATGGG AAGGAACCCC TβββACAGCC CCTGCCCTGC TAGATCTTTG 660
CCTCAGATTG CTGCTGTGGC CAβGCCCAGG ATTTCCAGCC CTATGGCTCT GAβTCCTCAC 720
ATGCTGGGGG CCCAGGGGAT ATGGACACAC TCCATCCAGG GATCCCTTCC TGCCATCTGG 780
GCAGCAACCA TβGGGACAAA GGGAGGAAGC AGAGTCCTGT TTCCTTGCCA CTTGTCCAAG 840
GCACTTCCCC ATCCTGACAG CGGCCCCCAC CCAGCCCAGG ATCCTGGGCT GTGβTCTCAA 900
GCTCACTTCC CATTATCTTT GGGGCTGGGG CTGACATCAG GAGβACATCT βACTGGTGGA 960
TGGAGCCAβC CTGGGAACAT CGCAGCTGGG GCAβTGCCTA βGGCTCTCCC TTCCCAGGGA 1020
GACATGβAβA AGGGββTTGA GGGAGGGCCC TTCCCTAGCC GCTGTGGCAA CTCCAGTGAG 1080
CTGTTCTGGG CAAAGTGTGG CCCAAGTCGG CAGCCCCAGC CCTGCAGTGC TββGGACGCT 1140
GACAGGACAC GGGAAβAGGC CATGCTTTCC CTCGGGACCT GCTβTTCCAT GTβTCCCAAG 1200
CCCTCCTβCT TTCCAGATGG CCCCTCAGGA AACCACCTTT CCAGGGCCTC TGCTCCCTTG 1260
GGCGCTCGCT GGGTCTGCAT CAACGGAGTG TGGGTAβAGC CGGβAGGACC CAGCCCTGCC 1320
AββCTGAAGG AGGGCTCCTC ACGGACACAC AGGCCAGGAG GCAAGCGTGG GCGTCTTGCG 1380
GβCGβTAGCG CCGACACTGT GCGCTCTCCT GCAGACAGCC TCTCCATGTC AAGCTTCCAG 1440
TCTGTCAAGT CCATCTCTAA TTCAGCCAAC TCTCAAGGCA AGGCCAGGCC CCAGCCCGGC 1500
TCCTTCAACA AGCAAGATTC AAAAβCTGAC GTCTCCCAGA AGGCGGACCT GGAAGAGGAG 1560
CCCCTACTTC ACAACAβCAA GCTββACAAA GTTCCTGGGG TACAAGGGCA GGCCAGAAAG 1620
GAGAAAGCAG AGGCCTCTAA TGCAGGAGCT GCCTGTATGG GGAACAGCCA GCACCAGβGC 1680
AGGCAGATGG ββGCGGGGGC ACACCCCCCA ATGATCCTGC CCCTTCCCCT GCGAAAGCCC 1740
ACCACACTTA GβCAGTGCGA AGTGCTCATC CGCGAGCTGT GGAATACCAA CCTCCTGCAG 1800
ACCCAAGAGC TGCβGCACCT CAAGTCCCTC CTGGAAGGGA GCCAGAGGCC CCAGGCAGCC 1860
CCGGAGGAAG CTAGCTTTCC CAGGGACCAA GAAGCCACGC ATTTCCCCAA GGTCTCCACC 1920
AAGAGCCTCT CCAAGAAATG CCTGAGCCCA CCTGTGGCGG AGCGTGCCAT CCTGCCCGCA 1980
CTGAAGCAGA CCCCGAAGAA CAACTTTGCC GAGAGGCAGA AGAGGCTGCA GGCAATGCAG 2040
AAACGGCGCC TGCATCGCTC AGTGCTTTGA
A24 Protein sequence:
Gene name-. ESTs
Unigene number: Hs.29383
Probeset Accession #: AW207206
Protein Accession #: T43457
Signal sequence: none found
Transmembrane domains: 303-322
Cellular Localization: not determined
1 11 21 31 41 51 1 1 11 11 11 11 11
MSGAGVAAβT RPPSSPTPβS RRRRQRPSVG VQSLRPQSPQ LRQSDPQKRN LDLEKSLQFL 60
QQQHSEMLAK LHEEIEHLKR ENKGEPARGP RPALPPQAHS TLPLPQHRNT AINSSTRLGS 120
GGTQDGEPLQ TVLAHLAALA PVCQPSGYRF WGTWTDAATS SRβWTMLCSQ AQHVLLSβSP 180
GPEVIAGRQV ATGCSPDLPP PSRAEMGRNP WDSPCPARSL PQIAAVARPR ISSPMALSPH 240
MLGAQGIWTH SIQGSLPAIW AATMβTKGGS RVLFPCHLSK ALPHPDSGPH PAQDPGLWSQ 300
AHFPLSLGLG LTSGβHLTβG WSQPGNIAAG AVPRALPSQG DMEKGVEGGP FPSRCGNSSE 360
LFWAKCGPSR QPQPCSAGDA DRTREEAMLS LGTCCSMCPK PSCFPDGPSG NHLSRASAPL 420
GARWVCINGV WVEPββPSPA RLKEGSSRTH RPGGKRGRLA GGSADTVRSP ADSLSMSSFQ 480
SVKSISNSAN SQGKARPQPG SFNKQDSKAD VSQKADLEEE PLLHNSKLDK VPGVQGQARK 540 EKAEASNAGA ACMGNSQHQG RQMGAGAHPP MILPLPLRKP TTLRQCEVLI RELWNTNLLQ 600 TQELRHLKSL LEGSQRPQAA PEEASFPRDQ EATHFPKVST KSLSKKCLSP PVAERAILPA 660 LKQTPKNNFA ERQKRLQAMQ KRRLHRSVL
A25 DNA SEQUENCE βene name: ESTs ; prolactin receptor Unigene number: Hs .25252 Probeset Accession #: AA057193 Nucleic Acid Accession #: NM_000949 Coding εequence : 285-2153 (underlined sequences correspond to start and stop codons)
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CβAβGCTGAA ATCCCCAGAC GCCGGTTTTC TGGGCTGββC TTTCTGCTTA CTCACTCCTT 60 CTCCCTCTTT CTCGATTTTA CCβACCGTTC GCGAAACAGC TTTCCACACA ATGGAGCTTC 120 ATβTCCTCGT GCAGβAAGTA CTCATCCACT βATGTGGCAG ACTTTGCTCC CTβACAAAAC 180 TAAAGAACTC TCCTATTCAT GGAGGCGAAC ACTGAGGATG CTTTCCACAT βAACCCTGAA 240 GTGAACTTCT GATACATTTC CTβCAβCAAG AGAAGGCAβC CAACATGAAG GAAAATGTGG 300 CATCTGCAAC CGTTTTCACT CTβCTACTTT TTCTCAACAC CTβCCTTCTG AATGGACAGT 360 TACCTCCTGG AAAACCTGAG ATCTTTAAAT GTCGTTCTCC CAATAAGGAA ACATTCACCT 420 GCTGGTGGAG GCCTGGGACA GATGGAββAC TTCCTACCAA TTATTCACTG ACTTACCACA 480 GGGAAGGAGA GACACTCATG CATGAATGTC CAGACTACAT AACCGGTGGC CCCAACTCCT 540 GCCACTTTGG CAAGCAGTAC ACCTCCATGT GGAGGACATA CATCATGATG GTCAATGCCA 600 CTAACCAGAT GGGAAGCACT TTCTCGGATG AACTTTATGT G6ACGTGACT TACATAGTTC 660 AGCCAGACCC TCCTTTGGAG CTGβCTGTGG AAGTAAAACA GCCAGAAGAC AGAAAACCCT 720 ACCTGTGGAT TAAATGGTCT CCACCTACCC TGATTGACTT AAAAACTGGT TGGTTCACGC 780 TCCTGTATGA AATTCGATTA AAACCCGAGA AAGCAGCTGA GTGGGAGATC CATTTTGCTC 840 GβCAβCAAAC AGAGTTTAAG ATTCTCAGCC TACATCCAββ ACACAAATAC CTTGTCCAGG 900 TTCGCTGCAA ACCAGACCAT GβATACTGGA GTGCATββAG TCCAGCGACC TTCATTCAGA 960 TACCTAGTGA CTTCACCATG AATGATACAA CCβTGTββAT CTCTGTGGCT GTCCTTTCTG 1020 CTβTCATCTG TTTGATTATT GTCTGGGCAG TGGCTTTGAA GGβCTATAGC ATGGTGACCT 1080 GCATCTTTCC βCCAβTTCCT GGGCCAAAAA TAAAAGGATT TGATGCTCAT CTGTTGGAGA 1140 AGGGCAACTC TGAAGAACTA CTβAGTGCCT TGGGATβCCA AGACTTTCCT CCCACTTCTG 1200 ACTATGAGGA CTTGCTGGTG GAGTATTTAG AAGTAGATGA TAGTGAGGAC CAGCATCTAA 1260 TGTCAGTCCA TTCAAAAβAA CACCCAAGTC AAGGTATβAA ACCCACATAC CTGGATCCTβ 1320 ACACTGACTC AGGCCGββββ AGCTGTGACA GCCCTTCCCT TTTGTCTGAA AAGTGTGAGG 1380 AACCCCAβGC CAATCCCTCC ACATTCTATG ATCCTGAββT CATTGAGAAG CCAGAGAATC 1440 CTβAAACAAC CCACACCTββ GACCCCCAGT GCATAAGCAT GGAAGGCAAA ATCCCCTATT 1500 TTCATGCTGG TββATCCAAA TβTTCAACAT GGCCCTTACC ACAGCCCAβC CAβCACAACC 1560 CCAGATCCTC TTACCACAAT ATTACTGATG TGTGTGAGCT GGCTβTβGβC CCTGCAGGTG 1620 CACCGGCCAC TCTGTTGAAT GAAGCAGGTA AAGATGCTTT AAAATCCTCT CAAACCATTA 1680 AGTCTAGAGA AGAGGGAAAG GCAACCCAGC AGAGGGAGGT AGAAAGCTTC CATTCTGAGA 1740 CTGACCAGGA TACGCCCTGG CTGCTβCCCC AGGAGAAAAC CCCCTTTGGC TCCGCTAAAC 1800 CCTTGGATTA TGTGGAGATT CACAAGGTCA ACAAAGATGG TGCATTATCA TTGCTACCAA 1860 AACAGAGAβA GAACAGCGGC AAGCCCAAGA AGCCCGGGAC TCCTGAGAAC AATAAGGAβT 1920 ATGCCAAGGT GTCCGGββTC ATGGATAACA ACATCCTGGT GTTGGTGCCA GATCCACATG 1980 CTAAAAACGT GGCTTGCTTT GAAGAATCAG CCAAAGAGGC CCCACCATCA CTTGAACAGA 2040 ATCAAGCTGA GAAAGCCCTG GCCAACTTCA CTGCAACATC AAGCAAGTGC AGGCTCCAGC 2100 TGGGTGGTTT GGATTACCTG GATCCCGCAT GTTTTACACA CTCCTTTCAC TGATAGCTTG 2160 ACTAATGGAA TβATTGGTTA AAATGTGATT TTTCTTCAGG TAACACTACA GAGTACGTGA 2220 AATGCTCAAG AATGTAGTCA GACTGACACT ACTAAAGCTC CCAGCTCCTT TCATGCTCCA 2280 TTTTTAACCA CTTGCCTCTT TCTCCAGCAG CTGATTCCAG AACAAATCAT TATGTTTCCT 2340 AACTGTGATT TGTAGATTTA CTTTTTGCTG TTAGTTATAA AACTATGTGT TCAATGAAAT 2400 AAAAGCACAC TGCTTAGTAT TCTTGAGGGA CAATGCCAAT AGGTATATCC TCTGGAAAAG 2460 GCTTTCATGA TTTGGCATGG βACAGACGGA AATGAAATTG TCAAAATTGT TTACCATAGA 2520 AAGATGACAA AAGAAAATTT TCCACATAGG AAAATGCCAT GAAAATTGCT TTTGAAAAAC 2580 AACTGCATAA CCTTTACACT CCTCGTCCAT TTTATTAGGA TTACCCAAAT ATAACCATTT 2640 AAAGAAAGAA TGCATTCCAG AACAAATTβT TTACATAAGT TCCTATACCT TACTGACACA 2700 TTGCTβATAT βCAAGTAAGA AAT
A26 Protein sequence: Gene name: ESTs; prolactin receptor Unigene number: Hs.25252 Probeset Accession #: AA057193 Protem Accession #: NP_000940 Signal sequence : 1-23 Transmembrane domains : 237-253 FN3 domains : 28-112, 127-215 Cellular Localization: plasma membrane
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MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY 60 SLTYHREGET LMHECPDYIT GβPNSCHFβK QYTSMWRTYI MMVNATNQMG SSFSDELYVD 120 VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW 180 EIHFAGQQTE FKILSLHPβQ KYLVQVRCKP DHβYWSAWSP ATFIQIPSDF TMNDTTVWIS 240 VAVLSAVICL II AVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD 300 FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL 360 SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ 420 PΞQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE 480
SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP 540
ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS 600 KCRLQLGGLD YLDPACFTHS FH
A27 DNA SEQUENCE
Gene name: Human neuropeptide receptor Yl (NPYYl)
Unigene number: Hs.169266
Probeset Accession #: L07615
Nucleic Acid Accession #: NM_000909.1
Coding sequence : 209-1363 (underlined sequences correspond to start and stop codons)
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CATTCCCACC CTTCCTTCTT TAATAAGCAG GAβCGAAAAA GACAAATTCC AAAβAββATT 60 βTTCAβTTCA AGGGAATGAA GAATTCAGAA TAATTTTGGT AAATGGATTC CAATATCβββ 120 AATAAGAATA AGCTGAACAG TTβACCTβCT TTGAAGAAAC ATACTGTCCA TTTGTCTAAA 180 ATAATCTATA ACAACCAAAC CAATCAAAAT GAATTCAACA TTATTTTCCC AGβTTGAAAA 240 TCATTCAGTC CACTCTAATT TCTCAGAβAA GAATGCCCAG CTTCTGGCTT TTGAAAATGA 300 TβATTGTCAT CTGCCCTTGG CCATGATATT TACCTTAGCT CTTGCTTATG GAβCTGTGAT 360 CATTCTTGGT GTCTCTGGAA ACCTGGCCTT βATCATAATC ATCTTGAAAC AAAAββAβAT 420 GAGAAATGTT ACCAACATCC TGATTGTGAA CCTTTCCTTC TCAGACTTGC TTGTTGCCAT 480 CATGTGTCTC CCCTTTACAT TTGTCTACAC ATTAATGGAC CACTGGGTCT TTGGTGAGGC 540 GATGTGTAAG TTGAATCCTT TTGTβCAATG TGTTTCAATC ACTGTβTCCA TTTTCTCTCT 600 GGTTCTCATT GCTGTGGAAC GACATCAGCT GATAATCAAC CCTCGAGGGT ββAGACCAAA 660 TAATAβACAT GCTTATGTAβ GTATTGCTβT GATTTGGGTC CTTGCTGTGG CTTCTTCTTT 720 GCCTTTCCTG ATCTACCAAG TAATGACT6A TGAGCCGTTC CAAAATGTAA CACTTGATGC 780 GTACAAAGAC ^AAATACGTGT GCTTTGATCA ATTTCCATCG GACTCTCATA GβTTGTCTTA 840 TACCACTCTC CTCTTGGTGC TGCAGTATTT TGGTCCACTT TGTTTTATAT TTATTTβCTA 900 CTTCAAGATA TATATACGCC TAAAAAGGAβ AAACAACATG ATGGACAAGA TβAβAGACAA 960 TAAGTACAGG TCCAGTβAAA CCAAAAGAAT CAATATCATG CTGCTCTCCA TTGTGGTAGC 1020 ATTTGCAGTC TGCTGβCTCC CTCTTACCAT CTTTAACACT GTGTTTGATT GGAATCATCA 1080 βATCATTβCT ACCTGCAACC ACAATCTGTT ATTCCTGCTC TGCCACCTCA CAGCAATGAT 1140 ATCCACTTGT GTCAACCCCA TATTTTATGG GTTCCTβAAC AAAAACTTCC AGAGAGACTT 1200 GCAGTTCTTC TTCAACTTTT GTGATTTCCG βTCTCβββAT GATGATTATG AAACAATAGC 1260 CATGTCCACG ATGCACACAG ATGTTTCCAA AACTTCTTTG AAGCAAGCAA GCCCAGTCGC 1320 ATTTAAAAAA ATCAACAACA ATGATGATAA TGAAAAAATC TGAAACTACT TATAGCCTAT 1380 GGTCCCGGAT GACATCTGTT TAAAAACAAG CACAACCTGC AACATACTTT GATTACCTβT 1440 TCTCCCAAGG AATGGGGTTG AAATCATTTG AAAATGACTA AGATTTTCTT GTCTTGCTTT 1500 TTACTGCTTT TGTTβTAGTT GTCATAATTA CATTTGGAAC AAAAGGTGTG GGCTTTGGGG 1560 TCTTCTGGAA ATAGTTTTGA CCAGACATCT TTGAAGTGCT TTTTGTGAAT TTATGCATAT 1620 AATATAAAGA CTTTTATACT GTACTTATTG GAATGAAATT TCTTTAAAGT ATTACGATGC 1680 GCTGACTTCA GAAGTACCTG CCATCCAATA CGGTCATTAG ATTGββTCAT CTTGATTAGA 1740 TTAGATTAGA TTAGATTGTC AACAβATTββ βCCATCCTTA CTTTATGATA GGCATCATTT 1800 TAβTβTβTTA CAATAβTAAC AGTATGCAAA AGCAGCATTC AGGAGCCGAA AGATAGTCTT 1860 GAAβTCATTC AGAAGTGβTT TGAGGTTTCT GTTTTTTGGT GGTTTTTGTT TGTTTTTTTT 1920 TTTTTTCACC TTAAGGGAββ CTTTCATTTC CTCCCGACTG ATTGTCACTT AAATCAAAAT 1980 TTAAAAATGA ATAAAAAβAC ATACTTCTCA GCTGCAAATA TTATGGAGAA TTGGGCACCC 2040 ACAββAATGA AGAGAβAAAG CAGCTCCCCA ACTTCAAAAC CATTTTGGTA CCTGACAACA 2100 AGAGCATTTT AGAGTAATTA ATTTAATAAA GTAAATTAGT ATTGCTGCAA ATAGCTAAAT 2160 TATATTTATT TGAATTGATβ GTCAAGAβAT TTTCCATTTT TTTTACAGAC TβTTCAβTβT 2220 TTGTCAAGCT TCTGGTCTAA TATGTACTCG AAAGACTTTC CGCTTACAAT TTGTAGAAAC 2280 ACAAATATCG TTTTCCATAC AβCAGTGCCT ATATAGTβAC TGATTTTAAC TTTCAATGTC 2340 CATCTTTCAA AGGAAβTAAC ACCAAGGTAC AATGTTAAAG GAATATTCAC TTTACCTAGC 2400 AGGGAAAAAT ACACAAAAAC TGCAGATACT TCATATAGCC CATTTTAACT TGTATAAACT 2460 GTGTGACTTG TGGCGTCTTA TAAATAATβC ACTGTAAAGA TTACTGAATA . GTTGTGTCAT 2520 GTTAATGTGC CTAATTTCAT GTATCTTGTA ATCATGATTG AGCCTCAGAA . TCATTTGβAG 2580 AAACTATATT TTAAAGAACA AGACATACTT CAATGTATTA TACAGATAAA . GTATTACATG 2640 TGTTTGATTT TAAAAGGGCG GACATTTTAT TAAAATCAAT ATTGTTTTTG . CTTTTTCTGA 2700 GGAβTCTCTT TCAGTTTCAT TTTTTCTCAT CCCATGACTT CCCTCCGATG 1 GT
A28 Protein sequence: Gene name: Human neuropeptide Y receptor Yl (NPYYl) mRNA, exon 2-3 and complete eds Unigene number: Hs.169266 Probeset Accession #: L07615 Protein Accession #: NP_000900.1 Signal sequence : none found Pfam domains: 7tm_l [57-91] Transmembrane domains: 39-61, 77-99, 118-139, 157-179, 212-234, 264-286,
300-322
Cellular Localization: plasma membrane
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MNSTLFSQVE NHSVHSNFSE KNAQLLAFEN DDCHLPLAMI FTLALAYGAV II GVSGNLA 60 LIIIILKQKE MRNVTNILIV NLSFSDLLVA IMCLPFTFVY TLMDHWVFGE AMCKLNPFVQ 120 CVSITVSIFS LVLIAVERHQ LIINPRGWRP NNRHAYVGIA VIWVLAVASS LPFLIYQVMT 180 DEPFQNVTLD AYKDKYVCFD QFPSDSHRLS YTTLLLVLQY FGPLCFIFIC YFKIYIRLKR 240 RNNMMDKMRD NKYRSSETKR INIMLLSIW AFAVCWLPLT IFNTVFDWNH QIIATCNHNL 300 LFLLCHLTAM ISTCVNPIFY GFLNKNFQRD LQFFFNFCDF RSRDDDYETI AMSTMHTDVS 360 KTSLKQASPV AFKKINNNDD NEKI
A29 DNA SEQUENCE
Gene name: Homo sapiens G protein-coupled receptor (HOT7T175)
Unigene number: Hs.208229
Probeset Accession #: AI819198
Nucleic Acid Accession #: NM_032551.1
Coding sequence: 1-1197 (underlined sequences correspond to start and stop codons)
10
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ATβCACACCβ TGGCTACGTC CGβACCCAAC GCGTCCTGGG GGGCACCGGC CAACGCCTCC 60
GGCTβCCCCβ βCTGTGGCGC CAACGCCTCG GACGGCCCAG TCCCTTCGCC βCββGCCGTβ 120
15 βACGCCTGGC TCGTGCCGCT CTTCTTCGCG GCGCTGATGC TGCTGGGCCT GGTββββAAC 180
TCGCTGGTCA TCTACGTCAT CTGCCGCCAC AAGCCGATGC GGACCGTGAC CAACTTCTAC 240
ATCGCCAACC TGGCGGCCAC GGACGTGACC TTCCTCCTGT GCTGCGTCCC CTTCACGβCC 300
CTGCTGTACC CGCTGCCCGG CTGGGTGCTβ GβCGACTTCA TGTGCAAGTT CGTCAACTAC 360
ATCCAGCAββ TCTCGGTGCA GGCCACβTGT GCCACTCTGA CCGCCATGAβ TGTGGACCGC 420 0 TGGTACGTβA CβGTGTTCCC GTTβCGCGCC CTGCACCGCC GCACGCCCCβ CCTβGCGCTG 480
GCTGTCAGCC TCAGCATCTG GGTAGGCTCT GCGGCGGTGT CTGCGCCGGT GCTCGCCCTG 540
CACCGCCTGT CACCCGGGCC GCGCGCCTAC TGCAβTGAGG CCTTCCCCAG CCGCβCCCTC 600
GAGCGCGCCT TCGCACTβTA CAACCTβCTβ βCβCTβTACC TGCTGCCGCT GCTCGCCACC 660
TGCGCCTGCT ATGCGGCCAT GCTGCGCCAC CTGGGCCGGG TCGCCGTGCG CCCCGCGCCC 720
25 GCCGATAGCG CCCTGCAβββ βCAGGTGCTG GCAGAGCCCβ CAGβCGCCGT GCGGGCCAAG 780
GTCTCGCGGC TGGTGβCGGC CGT6GTCCTG CTCTTCGCCβ CCTβCTββGG CCCCATCCAG 840
CTGTTCCTCG TGCTGCAGGC GCTGββCCCC GCGGGCTCCT GGCACCCACβ CAβCTACβCC 900
GCCTACGCGC TTAAGACCTG GGCTCACTβC ATβTCCTACA GCAACTCCGC GCTGAACCCG 960
CTGCTCTACG CCTTCCTGGG CTCGCACTTC CGACAGGCCT TCCGCCGCGT CTGCCCCTGC 1020
30 GCGCC6CGCC GCCCCCGCCG CCCCCGCCGG CCCGGACCCT CGβACCCCGC AGCCCCACAC 1080
GCββAβCTβC ACCGCCTGGG GTCCCACCCG GCCCCCGCCA GββCGCAGAA GCCAGGGAβC 1140 AβTβββCTββ CCGCGCGCGG GCTGTβCCTC CTGGGGGAGG ACAACGCCCC TCTCTGA
A30 Protein sequence
_> Gene name: Homo sapiens G protein-coupled receptor (H0T7T175) , mRNA
Unigene number: Hs.208229 Protein Accession #: AI8191981 Signal sequence: none found Pfam domains: 7tm_l [59-323]
40 Transmembrane domains: 43-65, 86-108, 122-144, 159-181, 203-225, 260-282 Cellular Localization: plasma membrane
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MHTVATSGPN ASWGAPANAS GCPGCGANAS DGPVPSPRAV DAWLVPLFFA ALMLLGLVGN 60
SLVIYVICRH KPMRTVTNFY IANLAATDVT FLLCCVPFTA LLYPLPGWVL GDFMCKFVNY 120
IQQVSVQATC ATLTAMSVDR YVTVFPLRA LHRRTPRLAL AVSLSIWVGS AAVSAPVLAL 180
50 HRLSPGPRAY CSEAFPSRAL ERAFALYNLL ALYLLPLLAT CACYAAMLRH LGRVAVRPAP 240
ADSALQGQVL AERAGAVRAK VSRLVAAWL LFAACWβPIQ LFLVLQALGP AGSWHPRSYA 300
AYALKTWAHC MSYSNSALNP LLYAFLGSHF RQAFRRVCPC APRRPRRPRR PGPSDPAAPH 360 AELHRLGSHP APARAQKPGS SGLAARβLCV LGEDNAPL
55 A31 DNA SEQUENCE
Gene name: CH22_FGENES.706; cadherin, EGF LAG seven-pass G-type receptor 1, flamingo (Drosophila) homolog (CELSR1)
Unigene number: Hs.252387
. Probeset Accession #: NM_014246
60 Nucleic Acid Accession #: NM_014246
Coding sequence: 1-9045 (underlined sequences correspond to start and stop codons)
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ATGGCGCCGC CGCCGCCGCC CGTGCTGCCC GTGCTGCTGC TCCTGGCCGC CGCCGCCGCC 60
CTGCCGGCGA TGGGGCTGCG AGCGGCCGCC TGGGAGCCβC GCGTACCCGG CGGGACCCGC 120
GCCTTCGCCC TCCGGCCCGG CTGTACCTAC GCGGTβGGCβ CCβCTTGCAC GCCCCβGGCG 180
CCβCβGGAGC TGCTGβACβT GGGCCGCGAT GGβCGGCTGG CAGGACGTCG βCβCβTCTCβ 240
70 GGCGCβGGGC GCCCGCTGCC GCTGCAAβTC CGCTTGGTGG CCCGCAβTβC CCCGACGGCG 300
CTGAGCCGCC GCCTGCββGC GCGCACGCAC CTTCCCGGCT GCGGAGCCCG TGCCCGGCTC 360
TβCGGAACCG GTGCCCGGCT CTGCGGGβCβ CTCTGCTTCC CCGTCCCCGG CGGCTGCGCG 420
GCCGCGCAGC ATTCGβCβCT CGCAGCTCCG ACCACCTTAC CCGCCTGCCG CTGCCCGCCG 480
CGCCCCAGGC CCCGCTGTCC CGGCCGTCCC ATCTGCCTGC CGCCGGGCGG CTCGGTCCβC 540
75 CTGCGTCTGC TGTGCGCCCT GCGβCGCGCG GCTGGCGCCG TCCGGGTGGG ACTGGCGCTβ 600
GAGGCCGCCA CCGCGGGGAC GCCCTCCGCG TCβCCATCCC CATCGCCGCC CCTGCCGCCG 660
AACTTGCCCG AAGCCCGGGC GGGGCCGGCβ CGACβGGCCC GGCGβGGCAC GAGCβGCAGA 720
GGGAGCCTGA AGTTTCCGAT GCCCAACTAC CAGGTGGCGT TGTTTβAGAA CGAACCGGCG 780
GGCACCCTCA TCCTCCAGCT βCACGCGCAC TACACCATCG AGGGCGAGGA GGAGCGCGTG 840
80 AGCTATTACA TGGAGGββCT GTTCGACGAG CGCTCCCGββ GCTACTTCCG AATCGACTCT 900
GCCACGGGCG CCGTGAGCAC GGACAGCGTA CTGGACCGCG AGACCAAGGA GACGCACGTC 960
CTCAGGGTGA AAGCCGTGGA CTACAGTACG CCGCCGCGCT CGGCCACCAC CTACATCACT 1020
GTCTTGGTCA AAGACACCAA CGACCACAβC CCββTCTTCβ ACCAGTCGGA GTACCGCGAG 1080
CGCGTGCGGG AGAACCTGGA GβTGGGCTAC GAGGTβCTβA CCATCCGCGC CAβCGACCGC 1140 βACTCCCCCA TCAACβCCAA CTTβCGTTAC CGCGTGTTGG GGGGCGCGTG GGACGTCTTC 1200 CAGCTCAACG AGAGCTCTGG CGTβGTGAGC ACACGGGCGG TGCTGGACCG GGAGGAGGCG 1260 βCCGAGTACC AGCTCCTGGT GGAGGCCAAC GACCAGGGGC GCAATCCGGG CCCGCTCAGT 1320 GCCACGGCCA CCGTGTACAT CGAββTGGAG GACGAGAACG ACAACTACCC CCAGTTCAGC 1380 GAGCAGAACT ACGTGGTCCA GGTGCCCGAG GACGTGGGGC TCAACACββC TGTGCTGCGA 1440 GTGCAβGCCA CGGACCGGβA CCAGGGCCAG AACGCGGCCA TTCACTACAG CATCCTCAGC 1500. GGGAACGTGG CCGGCCAGTT CTACCTGCAC TCGCTGAGCG GGATCCTGGA TGTGATCAAC 1560 CCCTTGGATT TCGAGGATGT CCAGAAATAC TCGCTGAGCA TTAAGGCCCA GGATGGGGGC 1620 CGGCCCCCGC TCATCAATTC TTCAGGGGTG GTGTCTGTGC AGGTGCTGGA TGTCAACGAC 1680 AACGAGCCTA TCTTTGTGAG CAGCCCCTTC CAGGCCACGG TGCTGGAGAA TGTGCCCCTG 1740 GGCTACCCCG TGGTGCACAT TCAGGCGGTG GACGCGGACT CTGGAGAβAA CGCCCGGCTG 1800 CACTATCGCC TGGTGβACAC GGCCTCCACC TTTCTGββGG GCGGCAGCGC TGGGCCTAAG 1860 AATCCTGCCC CCACCCCTGA CTTCCCCTTC CAβATCCACA ACAGCTCCGG TTGGATCACA 1920 GTGTGTGCCβ AGCTGβACCβ CGAGβAGGTG GAGCACTACA GCTTCGGGGT GGAGGCGGTG 1980 GACCACGGCT CGCCCCCCAT GAGCTCCTCC ACCAGCβTGT CCATCACGGT GCTGGACGTG 2040 AATGACAACG ACCCGβTGTT CACGCAβCCC ACCTACβAβC TTCGTCTGAA TGAGGATGCG 2100 GCCGTGGGGA GCAGCβTGCT GACCCTβCAG GCCCGCβACC GTGACGCCAA CAβTGTβATT 2160 ACCTACCAβC TCACAGGCGG CAACACCCGG AACCGCTTTG CACTCAGCAβ CCAGAGAGββ 2220 GGCGGCCTCA TCACCCTGβC GCTACCTCTG βACTACAAGC AGGAGCAGCA βTACGTGCTG 2280 GCGGTGACAG CATCCβACCβ CACACGGTCG CACACTβCGC ATGTCCTAAT CAACGTCACT 2340 GATGCCAACA CCCACAGGCC TGTCTTTCAG AGCTCCCATT ACACAGTGAG TGTCAGTGAG 2400 GACAGGCCTG TGGGCACCTC CATTGCTACC CTCAGTGCCA ACCATGA6GA CACAGGAGAG 2460 AATGCCCGCA TCACCTACGT GATTCAGGAC CCCGTGCCGC AGTTCCGCAT TGACCCCGAC 2520 AGTGGCACCA TGTACACCAT GATGGAGCTG GACTATGAGA ACCAGGTCGC CTACACGCTG 2580 ACCATCATGG CCCAGGACAA CGGCATCCCβ CAGAAATCAG ACACCACCAC CCTAGAβATC 2640 CTCATCCTCG ATGCCAATGA CAATβCACCC CAGTTCCTGT GGGATTTCTA CCAGGGTTCC 2700 ATCTTTGAGG ATGCTCCACC CTCGACCAGC ATCCTCCAGG TCTCTGCCAC βGACCGGGAC 2760 TCAGGTCCCA ATGGβCGTCT GCTGTACACC TTCCAGGβTG GGGACβACGG CGATGGGGAC 2820 TTCTACATCG AGCCCACGTC CGGTGTGATT CGCACCCAGC GCCGβCTGGA CCGGGAGAAT 2880 GTGGCCGTβT ACAACCTTTβ GGCTCTGGCT GTGGATCGGG GCAGTCCCAC TCCCCTTAβC 2940 βCCTCGGTAG AAATCCAGGT GACCATCTTG GACATTAATG ACAATGCCCC CATGTTTGAG 3000 AAGGACGAAC TGGAGCTGTT TGTTGAGGAG AACAACCCAG TGGGGTC6GT GGTGGCAAAG 3060 ATTCGTGCTA ACGACCCTGA TGAAGGCCCT AATGCCCAGA TCATGTATCA GATTGTGGAA 3120 GGGGACATGC GGCATTTCTT CCAGCTGGAC CTGCTCAACG GGGACCTGCβ TGCCAT6GTG 3180 GAGCTGGACT TTGAGGTCCG GCGGGAGTAT GTGCTGGTGG TGCAGGCCAC GTCGGCTCCG 3240 CTGGTGAGCC GAGCCACGGT GCACATCCTT CTCGTGGACC AGAATGACAA CCCGCCTGTG 3300 CTGCCCGACT TCCAGATCCT CTTCAACAAC TATGTCACCA ACAAGTCCAA CAGTTTCCCC 3360 ACCGGCGTGA TCGGCTGCAT CCCGGCCCAT GACCCCGACG TGTCAGACAG CCTCAACTAC 3420 ACCTTCGTGC AGGGCAACGA GCTGCGCCTG TTGCTβCTGG ACCCCGCCAC GββCGAACTG 3480 CAGCTCAGCC GCGACCTGGA CAACAACCGG CCGCTGGAGG CGCTCATGGA GGTGTCTGTG 3540 TCTβATGβCA TCCACAGCGT CACGGCCTTC TGCACCCT6C GTGTCACCAT CATCACGGAC 3600 GACATGCTGA CCAACAGCAT CACTGTCCGC CTGGAGAACA TGTCCCAGGA GAAGTTCCTG 3660 TCCCCGCTGC TGGCCCTCTT CGTGGAGGGG βTGGCCGCCG TGCTGTCCAC CACCAAGGAC 3720 GACGTCTTCG TCTTCAACβT CCAβAACGAC ACCGACGTCA GCTCCAACAT CCTGAACGTG 3780 ACCTTCTCβG CGCTGCTGCC TGGCGβCGTC CGCGGCCAGT TCTTCCCGTC GGAβGACCTG 3840 CAGGAβCAGA TCTACCTGAA TCGGACGCTG CTGACCACCA TCTCCACβCA GCGCGTGCTG 3900 CCCTTCGACG ACAACATCTβ CCTGCGCGAG CCCTGCGAGA ACTACATβAA GTGCGTGTCC 3960 GTTCTGCGAT TCGACAGCTC CGCGCCCTTC CTCAGCTCCA CCACCGTGCT CTTCC6GCCC 4020 ATCCACCCCA TCAACGGCCT GCGCTGCCβC TβCCCGCCCG GCTTCACCGG CGACTACTGC 4080 GAGACGGAGA TCGACCTCTG CTACTCCGAC CCGTGCGβCG CCAACGGCCG CTGCCGCAGC 4140 CGCGAGGGCG GCTACACCTβ CGAGTβCTTC GAβGACTTCA CTGGAGAGCA CTGTGAGGTG 4200 GATβCCCGCT CAGGCCGCTG TGCCAACGGG GTGTGCAAGA ACGGGGGCAC CTGCGTGAAC 4260 CTGCTCATCG GCGGCTTCCA CTGCGTGTGT CCTCCTGGCG AGTATGAGAG GCCCTACTGT 4320 GAGGTGACCA CCAGGAGCTT CCCGCCCCAG TCCTTCGTCA CCTTCCGGGG CCTGAGACAG 4380 CGCTTCCACT TCACCATCTC CCTCACGTTT GCCACTCAGG AAAGGAACGG CTTGCTTCTC 4440 TACAACGGCC GCTTCAATGA GAAGCACGAC TTCATCGCCC TGGAβATCGT βGACGAGCAG 4500 GTGCAGCTCA CCTTCTCTGC AGGCGAGACA ACAACβACCG TGGCACCGAA βGTTCCCAGT 4560 GGTGTβAGTG ACGGGCGGTG GCACTCTGTG CAGGTGCAGT ACTACAACAA GCCCAATATT 4620 GGCCACCTGG GCCTGCCCCA TGGGCCGTCC GGGGAAAAGA TGGCCGTββT GACAGTGGAT 4680 GATTGTGACA CAACCATGGC TGTGCGCTTT GGAAAGGACA TCGGGAACTA CAGCTGCGCT 4740 GCCCAβGGCA CTCAGACCGG CTCCAAGAAG TCCCTGGATC TGACCGGCCC TCTACTCCTG 4800 GGGGGTGTCC CCAACCTGCC AGAAGACTTC CCAGTGCACA ACCGGCAGTT CGTGGGCTβC 4860 ATGCGGAACC TβTCAGTCGA CGGCAAAAAT GTGGACATGG CCGGATTCAT CβCCAACAAT 4920 GGCACCCGβG AAGGCTGCGC TGCTCGGAGG AACTTCTGCG ATGGGAGβCG GTGTCAGAAT 4980 GGAGGCACCT GTGTCAACAG GTGGAATATG TATCTGTGTβ AGTGTCCACT CCGATTCGGC 5040 GGGAAGAACT GTGAGCAAGC CATGCCTCAC CCCCAGCTCT TCAGCGGTGA GAGCGTCGTβ 5100 TCCTGGAGTG ACCTGAACAT CATCATCTCT GTGCCCTGGT ACCTββGGCT CATGTTCCGG 5160 ACCCGGAAGG AGGACAGCGT TCTGATGGAG GCCACCAGTG GTGGGCCCAC CAGCTTTCCC 5220 CTCCAGATCC TGAACAACTA CCTCCAGTTT GAGGTGTCCC ACGGCCCCTC CGATGTGGAG 5280 TCCGTGATGC TGTCCGGGTT GCGGGTGACC GACGGGGAGT GGCACCACCT GCTGATCGAG 5340 CTGAAGAATG TTAAGGAGGA CAGTGAGATG AAGCACCTGG TCACCATGAC CTTGGACTAT 5400 GGGATGGACC AGAACAAGGC AGATATCGGG GβCATβCTTC CCGββCTGAC GGTAAGGAβC 5460 GTGGTGGTCG GAGβCβCCTC TGAAGACAAG GTCTCCGTGC GCCGTGGATT CCGAGGCTGC 5520 ATGCAGGGAG TGAGβATGGβ GGGGACGCCC ACCAACGTCG CCACCCTβAA CATGAACAAC 5580 GCACTCAAGG TCAGββTGAA GGACGβCTβT βATGTGGACG ACCCCTGTAC CTCGAGCCCC 5640 TGTCCCCCCA ATAGCCGCTG CCACβACβCC TββGAGGACT ACAGCTGCGT CTGTGACAAA 5700 GGGTACCTTG GAATAAACTG TGTGGATβCC TGTCACCTGA ACCCCTGCGA GAACATGGGG 5760 GCCTGCGTGC GCTCCCCCGG CTCCCCGCAG GGCTACGT6T GCGAβTβTGG GCCCAGTCAC 5820 TACGβGCCGT ACTβTGAGAA CAAACTCGAC CTTCCGTGCC CCAGAGGCTG GTβGGβGAAC 5880 CCCGTCTGTG GACCCTGCCA CTGTGCCβTC ACCAAAGGCT TTGATCCCGA CTGTAATAAβ 5940 ACCAACGGCC AGTGCCAATG CAAGGAGAAT TACTACAAGC TCCTAGCCCA βGACACCTGT 6000 CTGCCCTGCG ACTGCTTCCC CCATGGCTCC CACAGCCGCA CTTGCGACAT GGCCACCGGG 6060 CAGTGTGCCT GCAAβCCCGG CGTCATCGGC CGCCAGTGCA ACCβCTβCβA CAACCCβTTT 6120 GCCGAβGTCA CCACGCTCβG CTGTGAAβTβ ATCTACAATβ GCTGTCCCAA AGCATTTGAG 6180 GCCββCATCT GGTGGCCACA GACCAAGTTC GGGCAGCCGG CTGCGGTGCC ATGCCCTAAG 6240
GβATCCβTTβ GAAATGCGGT CCβACACTGC AGCGGGGAGA AGGGCTβGCT GCCCCCAGAG 6300
CTCTTTAACT GTACCACCAT CTCCTTCGTG GACCTCAGGG CCATGAATβA βAAβCTβAβC 6360
CGCAATGAGA CGCAGβTGGA CGGCGCCAGG βCCCTGCAGC TGGTGAβGGC GCTGC6CAGT 6420
GCTACACAGC ACACGββCAC GCTCTTTGβC AATGACGTGC βCACββCCTA CCA6CTGCTG 6480
GGCCACGTCC TTCAGCACβA GAGCTGβCAβ CACGGCTTCG ACCTGGCAGC CACGCAGGAC 6540
GCCGACTTTC ACGAGGACGT CATCCACTCG GGCAGCGCCC TCCTGGCCCC AGCCACCAGG 6600
GCGGCGTGGG AGCAGATCCA GCGGAGCGAG GGCGGCACGG CACAGCTGCT CCββCGCCTC 6660
GAGGβCTACT TCAGCAACGT GGCACGCAAC GTGCGGCGGA CGTACCTGCG GCCCTTC6TC 6720
ATCβTCACCG CCAACATGAT TCTTGCTGTC GACATCTTTG ACAAGTTCAA CTTTACGGGA 6780
GCCAGβGTCC CGCGATTCGA CACCATCCAT GAAGAGTTCC CCAGGGAGCT GGAGTCCTCC 6840
GTCTCCTTCC CAGCCβACTT CTTCAGACCA CCTGAAGAAA AAGAAGGCCC CCTGCTGAGG 6900
CCGGCTGGCC GGAGGACCAC CCCGCAGACC ACGCGCCCGG GGCCTGGCAC CGAGAGGGAG 6960
GCCCCβATCA GCAGGCGGAβ GCβACACCCT βATβACβCTG GCCAGTTCGC CGTCGCTCTG 7020
GTCATCATTT ACCGCACCCT GGGGCAGCTC CTGCCCβAβC βCTACGACCC CGACCGTCGC 7080
AGCCTCCGGT TGCCTCACCG GCCCATCATT AATACCCCGA TGGTGAGCAC GCTGGTGTAC 7140
AGCGAGGβGG CTCCGCTCCC GAGACCCCTG GAGAGGCCCG TCCTββTGGA GTTCGCCCTG 7200
CTGGAGGTGG AGGAGC6AAC CAAGCCTGTC TGCGTGTTCT GGAACCACTC CCTGGCCGTT 7260
GβTGGGACGG GAGββTβGTC TGCCCGGGGC TGCGAGCTCC TGTCCAGGAA CCGβACACAT 7320
GTC6CCTGCC AGTGCAGCCA CACAGCCAGC TTTGCGGTGC TCATGGATAT CTCCAGGCGT 7380
GAβAACβGGG AGGTCCTGCC TCTβAAGATT GTCACCTATG CCGCTGTGTC CTTGTCACTG 7440
GCAGCCCTGC TGGTGGCCTT CGTCCTCCTG AGCCTGGTCC βCATβCTGCG CTCCAACCTG 7500
CACAGCATTC ACAAGCACCT CGCCGT6GCG CTCTTCCTCT CTCAβCTGβT GTTCGTGATT 7560
GGGATCAACC AGACGβAAAA CCCGTTTCTG TβCACAGTGG TTGCCATCCT CCTCCACTAC 7620
ATCTACATGA GCACCTTTGC CTGGACCCTC GTβGAGAGCC TGCATGTCTA CCGCATβCTβ 7680
ACCβAGGTGC GCAACATCGA CACGGGGCCC ATGCGGTTCT ACTACGTCGT GGGCTGGGβC 7740
ATCCCGGCCA TTGTCACAββ ACTββCGGTC GGCCTGGACC CCCAβGGCTA CGGGAACCCC 7800
GACTTCTGCT βGCTGTCGCT TCAAGACACC CTGATTTGGA βCTTTβCGGβ βCCCATCGGA 7860 βCTGTTATAA TCATCAACAC AGTCACTTCT GTCCTATCTG CAAAβGTTTC CTGCCAAAGA 7920
AAGCACCATT ATTATGGGAA AAAAGGGATC GTCTCCCTGC TβAβGACCGC ATTCCTCCTG 7980
CTGCTGCTCA TCAGCGCCAC CTGβCTCCTG GGGCTGCTGG CTGTβAACCβ CGATGCACTG 8040
AGCTTTCACT ACCTCTTCGC CATCTTCAGC GGCTTACAGG GCCCCTTCGT CCTCCTTTTC 8100
CACTGCGTGC TCAACCAGGA GGTCCGGAAβ CACCTGAAGG GCGTGCTCGβ CβββAββAAβ 8160
CTGCACCTGβ AGGACTCCGC CACCACCAGG GCCACCCTGC TGACGCGCTC CCTCAACTGC 8220
AACACCACCT TCGGTGACGG GCCTGACATG CTGCGCACAβ ACTTGGGCGA GTCCACCβCC 8280
TCGCTGGACA GCATCβTCAβ GGATGAAGGG ATCCAGAAGC TCGGCGTGTC CTCTGGGCTβ 8340
GTGAGGGGCA GCCACββAGA GCCAGACGCG TCCCTCAT6C CCAGGAGCTG CAAGGATCCC 8400
CCTGGCCACG ATTCCGACTC AβATAGCGAG CTGTCCCTββ ATGAGCAGAG CAGCTCTTAC 8460
GCCTCCTCAC ACTCGTCAGA CAβCGAGGAC GATGGGGTGG GAGCTβAGGA AAAATGGGAC 8520
CCGGCCAβββ βCGCCGTCCA CAGCACCCCC AAAGGGGACG CTGTββCCAA CCACGTTCCG 8580
GCCGGCTGβC CCGACCAGAG CCTββCTβAβ AGTGACAGTG AGGACCCCAG CGGCAA6CCC 8640
CGCCTGAAGβ TGGAGACCAA GGTCAβCGTG βAGCTGCACC GCβAββAβCA GGGCAGTCAC 8700
CGTGGAGAβT ACCCCCCGGA CCAGGAβAGC GGGGGCGCAG CCAGGCTTGC TAGCAGCCAG 8760
CCCCCAGAGC A6A6GAAAGG CATCTTGAAA AATAAAGTCA CCTACCCGCC GCCGCT6ACG 8820
CTGACGGAGC AGACGCTGAA GGGCCββCTC CGGGAGAAGC TGGCCGACTβ TGAβCAβAGC 8880
CCCACATCCT CGCGCACGTC TTCCCTGGGC TCTGGCGGCC CCGACTGCGC CATCACAGTC 8940
AAβAGCCCTG GGAβGGAGCC GGGGCGTGAC CACCTCAACG GGGTGGCCAT GAATβTGCGC 9000
ACTβββAGCG CCCAGGCCGA TGGCTCCGAC TCTGAGAAAC CGTGAGGCAA GCCCGTCACC 9060
CCACACAGGC TGCGGCATCA CCCTCAGACC TTGGAGCCCA AGGGGCCACT GCCCTTGAAβ 9120
TGGAGTGGGC CCAGAGTGTG GCGβTCCCCA TGGTGGCAGC CCCCCGACTG ATCATCCAGA 9180
CACAAAGGTC TTGβTTCTCC CAGGAGCTCA GGGCCTGTCA GACCTGGTGA CAAGTGCCAA 9240
AGβCCACAGG CATGAβGGAG GCGTGGACCA CTGGGCCAGC ACCGCTGAGT CCTAAGACTG 9300
CAGTCAAAGC CAGAACTGAG AGGGGACCCC AGACTGβGCC CAGAGGCTGG CCAGAGTTCA 9360
GGAACGCCGG GCACAGACCA AAβACCGCGG TCCAGCCCCG CCCAGGCGGG CATCTCATGG 9420
CAGTGCGGAC CCGTGGCTGG CAGCCCGGGC AGTCCTTTGC AAAGβCACCC CTTGTCTTAA 9480
AATCACTTCG CTATGTGGGA AAGGTGβAGA TACTTTTATA TATTTGTATG βGACTCTGAβ 9540
GAGGTGCAAC CTGTATATAT ATTGCATTCG TGCTGACTTT GTTATCCCGA GAGATCCATG 9600
CAATGATCTC TTGCTGTCTT CTCTGTCAAG ATTGCACAGT TGTACTTGAA TCTGGCATβT 9660
GTTGACGAAA CTGGTGCCCC AGCAGATCAA AGGTGGGAAA TACGTCAGCA GTGGGGCTAA 9720
AACCAAGCGG CTAGAAGCCC TACAGCTGCC TTCGGCCAGG AAGTβAGGAT GGTGTGGGCC 9780
CTCCCCGCCG GCCCCCTGββ TCCCCAGTGT TCGCTGTGTG TβCGTTTGTC CTCTGCTGCC 9840
ATCTGCCCCG GCTGTGTGAA TTCAAGACAG GGCAGTGCAβ CACTAGGCAG GTGTGAGGAG 9900
CCCTGCTβAβ GTCACTGTGG GGCACGGTTG CCACACGGCT GTCATTTTTC ACCTGβTCAT 9960
TCTGTGACCA CCACCCCCTC CCCTCACCGC CTCCCAGGTG GCCCGGGAGC TGCAGGTGGG 10020
GATβGCTTTG TCCTTTGCTC CTGCTCCCCG TGGGACCTGG GACCTTAAAG CβTTβCAββT 10080
TCCTβATTTG GACAGAββTG TGGGGCCTTC CAGGCCGTTA CATACCTCCT GCCAATTCTC 10140
TAACTCTCTG AGACTGCGAG GATCTCCAGG CAGGGTTCTC CCCTCTGGAG TCTGACCAAT 10200
TACTTCATTT TGCTTCAAAT GGCCAATTGT GCAGAGGβAC AAAGCCACAG CCACACTCTT 10260
CAACGGTTAC CAAACTGTTT TTGGAAATTC ACACCAAββT CGβGCCCACT GCAβGCAGCT 10320
GGCACAGCGT GGCCCβAββG GCTGTGGAAC GGGTCCCGGA ACTGTCAGAC ATGTTTGATT 10380
TTAGCGTTTC CTTTGTTCTT CAAATCAββT GCCCAAATAA GT6ATCAGCA CAGCTβCTTC 10440
CAAATAGGAG AAACCATAAA ATAGβATGAA AATCAAGTAA AATGCAAAβA TGTCCACACT 10500
GTTTTAAACT TGACCCTCAT GAAAATGTGA GCACTGTTAG CAGATGCCTA TGGGAGAGGA 10560
AAAGCGTATC TGAAAATβGT CCAGGACAGG AGGATGAAAT GAGATCCCAβ AGTCCTCACA 10620
CCTGAATGAA TTATACATGT GCCTTACCAG GTGAGTGGTC TTTCGAAGAT AAAAAACTCT 10680
AGTCCCTTTA AACGTTTGCC CCTGβCGTTT CCTAAβTACG AAAAGGTTTT TAAGTCTTCG 10740
AACAGTCTCC TTTCATGACT TTAACAGGAT TCTGCCCCCT GAGGTGTAAT TTTTTTGTTC 10800 TATTTTTTTC CACβTACTCC ACAβCCAACA TCACGAGGTG TAATTTTTAA TTTGATCAGA 10860
ACTGTTACCA AAAAACAACT GTCAGTTTTA TTGAGATGGG AAAAATGTAA ACCTATTTTT 10920
ATTACTTAAG ACTTTATGββ AGAGATTAGA CACTGGAGGT TTTTAACAGA ACGTGTATTT 10980
ATTAATGTTC AAAACACTGG AATTACAAAT GAGAAGAGTC TACAATAAAT TAAGATTTTT 11040 GAATTTGTAC TTCTGCGGTG CTGGTTTTTC TCCACAAACA CCCCCGCCCC TCCCCATGCC 11100 CAGGβTββCC GTGβAAβββA CGGTTTACGG ACGTGCAGCT GAGCTβTCCβ TGTCCCATGC 11160 TCCCTCAGCC AGTGGAACGT GCCGGAACTT TTTGTCCATT CCCTAGTAβG CCTGCCACAG 11220 CC AGATGGβ CAGTTTTTGT CTTTCACCAA ATTTGAGGAC TTTTTTTTTT TGCCATTATT 11280 TCTTCAGTTT TCTTTTCTTG CACTGATCTT TCTCCTCTCC TTCTβTβACT CCAGTGACTC 11340 AGACGTTAGA CCTCTTGATβ TTTTCCCACT GβTCCCTGAG GCTCTβTTC
A32 Protein Sequence Gene name: CH22_FGENES.706; cadherin, EGF LAG seven-pass G-type receptor 1, flamingo (Drosophila) homolog (CELSR1) ,
Unigene number: Hs.252387 Protein Accession #: NP 055061 Signal sequence : 1-20 Cadherin domains: 250-344, 358-449, 464-556, 570-678, 692-780, 794-883, 897-990, 1004-1092,
1110-1199
Pfam domains : Laminin_EGF [2003-2048], 7tm_2 [2465-2708] Latrophilin/GPS domains : 2407-2460 Transmembrane domains : 1219-1238, 2473-2492, 2507-2522, 2529-2547, 2616-2634, 2659-2675, 2687-2704 Cellular Localization: plasma membrane
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MAPPPPPVLP VLLLLAAAAA LPAMGLRAAA WEPRVPGGTR AFALRPGCTY AVGAACTPRA 60 PRELLDVGRD GRLAGRRRVS GAGRPLPLQV RLVARSAPTA LSRRLRARTH LPGCGARARL 120 CGTGARLCGA LCFPVPGGCA AAQHSALAAP TTLPACRCPP RPRPRCPGRP ICLPPGGSVR 180 LRLLCALRRA AGAVRVGLAL EAATAGTPSA SPSPSPPLPP NLPEARAGPA RRARRGTSGR 240 GSLKFPMPNY QVALFENEPA GTLILQLHAH YTIEβEEERV SYYMEGLFDE RSRGYFRIDS 300 ATGAVSTDSV LDRETKETHV LRVKAVDYST PPRSATTYIT VLVKDTNDHS PVFEQSEYRE 360 RVRENLEVGY EVLTIRASDR DSPINANLRY RVLGGAWDVF QLNESSGWS TRAVLDREEA 420 AEYQLLVEAN DQGRNPGPLS ATATVYIEVE DENDNYPQFS EQNYWQVPE DVGLNTAVLR 480 VQATDRDQGQ NAAIHYSILS GNVAβQFYLH SLSβlLDVIN PLDFEDVQKY SLSIKAQDGG 540 RPPLINSSGV VSVQVLDVND NEPIFVSSPF QATVLENVPL GYPWHIQAV DADSGENARL 600 HYRLVDTAST FLGGGSAGPK NPAPTPDFPF QIHNSSβWIT VCAELDREEV EHYSFGVEAV 660 DHGSPPMSSS TSVSITVLDV NDNDPVFTQP TYELRLNEDA AVGSSVLTLQ ARDRDANSVI 720 TYQLTGGNTR NRFALSSQRG βGLITLALPL DYKQEQQYVL AVTASDGTRS HTAHVLINVT 780 DANTHRPVFQ SSHYTVSVSE DRPVGTSIAT LSANDEDTβE NARITYVIQD PVPQFRIDPD 840 SβTMYTMMEL DYENQVAYTL TIMAQDNGIP QKSDTTTLEI LILDANDNAP QFLWDFYQGS 900 IFEDAPPSTS ILQVSATDRD SGPNGRLLYT FQGβDDGDGD FYIEPTSGVI RTQRRLDREN 960 VAVYNLWALA VDRβSPTPLS ASVEIQVTIL DINDNAPMFE KDELELFVEE NNPVGSWAK 1020 IRANDPDEGP NAQIMYQIVE GDMRHFFQLD LLNβDLRAMV ELDFEVRREY VLWQATSAP 1080 LVSRATVHIL LVDQNDNPPV LPDFQILFNN YVTNKSNSFP TGVIGCIPAH DPDVSDSLNY 1140 TFVQGNELRL LLLDPATGEL QLSRDLDNNR PLEALMEVSV SDGIHSVTAF CTLRVTIITD 1200 DMLTNSITVR LENMSQEKFL SPLLALFVEG VAAVLSTTKD DVFVFNVQND TDVSSNILNV 1260 TFSALLPGGV RGQFFPSEDL QEQIYLNRTL LTTISTQRVL PFDDNICLRE PCENYMKCVS 1320 VLRFDSSAPF LSSTTVLFRP IHPINGLRCR CPPGFTGDYC ETEIDLCYΞD PCGANGRCRS 1380 REGGYTCECF EDFTGEHCEV DARSGRCANG VCKNGβTCVN LLIGGFHCVC PPGEYERPYC 1440 EVTTRSFPPQ SFVTFRGLRQ RFHFTISLTF ATQERNGLLL YNβRFNEKHD FIALEIVDEQ 1500 VQLTFSAGET TTTVAPKVPS GVSDGRWHSV QVQYYNKPNI GHLβLPHGPS GEKMAWTVD 1560 DCDTTMAVRF GKDIGNYSCA AQGTQTGSKK SLDLTGPLLL GGVPNLPEDF PVHNRQFVGC 1620 MRNLSVDGKN VDMAGFIANN GTREGCAARR NFCDGRRCQN GGTCVNRWNM YLCECPLRFG 1680 GKNCEQAMPH PQLFSGESW SWSDLNIIIS VPWYLGLMFR TRKEDSVLME ATSGGPTSFR 1740 LQILNNYLQF EVSHGPSDVE SVMLSGLRVT DGEWHHLLIE LKNVKEDSEM KHLVTMTLDY 1800 GMDQNKADIG GMLPGLTVRS VWGGASEDK VSVRRGFRGC MQGVRMGGTP TNVATLNMNN 1860 ALKVRVKDGC DVDDPCTSSP CPPNSRCHDA WEDYSCVCDK GYLGINCVDA CHLNPCENMG 1920 ACVRSPGSPQ GYVCECGPSH YGPYCENKLD LPCPRGWWGN PVCGPCHCAV SKGFDPDCNK 1980 TNGQCQCKEN YYKLLAQDTC LPCDCFPHβS HSRTCDMATβ QCACKPGVIG RQCNRCDNPF 2040 AEVTTLGCEV IYNGCPKAFE AGIWWPQTKF GQPAAVPCPK GSVGNAVRHC SGEKGWLPPE 2100 LFNCTTISFV DLRAMNEKLS RNETQVDGAR ALQLVRALRS ATQHTGTLFG NDVRTAYQLL 2160 GHVLQHESWQ QβFDLAATQD ADFHEDVIHS GSALLAPATR AAWEQIQRSE GβTAQLLRRL 2220 EβYFSNVARN VRRTYLRPFV IVTANMILAV DIFDKFNFTG ARVPRFDTIH EEFPRELESS 2280 VSFPADFFRP PEEKEβPLLR PAGRRTTPQT TRPβPGTERE APISRRRRHP DDAβQFAVAL 2340 VIIYRTLGQL LPERYDPDRR SLRLPHRPII NTPMVSTLVY SE6APLPRPL ERPVLVEFAL 2400 LEVEERTKPV CVFWNHSLAV GGTGGWSARG CELLSKNRTH VACQCSHTAS FAVLMDISRR 2460 ENGEVLPLKI VTYAAVSLSL AALLVAFVLL SLVRMLRSNL HSIHKHLAVA LFLSQLVFVI 2520 GINQTENPFL CTWAILLHY IYMSTFAWTL VESLHVYRML TEVRNIDTGP MRFYYWGWβ 2580 IPAIVTGLAV GLDPQGYGNP DFCWLSLQDT LIWSFAGPIG AVIIINTVTS VLSAKVSCQR 2640 KHHYYGKKGI VSLLRTAFLL LLLISATWLL GLLAVNRDAL SFHYLFAIFS βLQGPFVLLF 2700 HCVLNQEVRK HLKGVLGGRK LHLEDSATTR ATLLTRSLNC NTTFGDGPDM LRTDLGESTA 2760 SLDSIVRDEG IQKLGVSSGL VRGSHGEPDA SLMPRSCKDP PGHDSDSDSE LSLDEQSSSY 2820 ASSHSSDSED DGVGAEEKWD PARβAVHSTP KGDAVANHVP AβWPDQSLAE SDSEDPSGKP 2880 RLKVETKVSV ELHREEQGSH RGEYPPDQES GGAARLASSQ PPEQRKGILK NKVTYPPPLT 2940 LTEQTLKβRL REKLADCEQS PTSSRTSSLG SGGPDCAITV KSPGREPGRD HLNGVAMNVR 3000 TβSAQADβSD SEKP
A33 DNA SEQUENCE
Gene name: CXCR3 (G protein-coupled receptor 9); chemokine (C-X-C) receptor 3
Unigene number: Hs.198252
Probeset Accession #.- X95876
Nucleic Acid Accession #: X95876
Coding sequence: 69-1175 (underlined sequences correspond to start and stop codons)
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CCAACCACAA GCACCAAACC AGAGβββCAG GCAGCACACC ACCCAGCAGC CAGAGCACCA 60 GCCCAGCCAT GGTCCTTGAβ GTGAGTβACC ACCAAβTGCT AAATGACGCC GAGGTTGCCG 120 CCCTCCTGGA GAACTTCAGC TCTTCCTATβ ACTATGGAGA AAACGAGAGT GACTCGTGCT 180 GTACCTCCCC GCCCTGCCCA CAββACTTCA GCCTGAACTT CGACCGGGCC TTCCTGCCAG 240 CCCTCTACAG CCTCCTCTTT CTGCTGβββC TβCTCGGCAA CGGCGCGGTG GCAGCCGTGC 300 TGCTβAGCCG GCGGACAGCC CTGAGCAGCA CCGACACCTT CCTGCTCCAC CTAGCTGTAG 360 CAGACACGCT GCTGGTGCTG ACACTGCCβC TCTβββCAGT GGACGCTβCC GTCCAGTGGβ 420 TCTTTβGCTC TGGCCTCTGC AAAGTGβCAβ βTGCCCTCTT CAACATCAAC TTCTACGCAG 480 GAGCCCTCCT GCTββCCTGC ATCAGCTTTG ACCβCTACCT GAACATAGTT CATGCCACCC 540 AGCTCTACCG CCGGββGCCC CCGGCCCGCβ TGACCCTCAC CTGCCTGGCT GTCTGGGββC 600 TCTGCCTβCT TTTCβCCCTC CCAGACTTCA TCTTCCTGTC GβCCCACCAC βACGAGCGCC 660 0 TCAACβCCAC CCACTβCCAA TACAACTTCC CACAGGTGGG CCβCACβGCT CTGCGGGTGC 720 TGCAGCTGGT GGCTG6CTTT CTGCTGCCCC TGCTGGTCAT GβCCTACTβC TATGCCCACA 780 TCCTGGCCGT GCTGCTGGTT TCCAGGGβCC AGCGGCGCCT GCβGGCCATG CGGCTGGTGG 840 TGGTGGTCGT GGTGGCCTTT GCCCTCTGCT GGACCCCCTA TCACCTGGTG GTGCTGGTGG 900 ACATCCTCAT GGACCTGGGC GCTTTGGCCC GCAACTGTGG CCβAGAAAGC AGGGTAGACG 960 5 TββCCAAβTC GGTCACCTCA GGCCTGGGCT ACATGCACTG CTGCCTCAAC CCGCTGCTCT 1020
ATβCCTTTβT AGGGGTCAAG TTCCGGGAGC GβATGTGGAT GCTGCTCTTG CGCCTGGGCT 1080
GCCCCAACCA GAGAGGβCTC CAGAGGCAGC CATCGTCTTC CCGCCβGGAT TCATCCTGGT 1140
CTGAGACCTC AGAβGCCTCC TACTCGGGCT TGTGAGβCCβ GAATCCGGGC TCCCCTTTCG 1200
CCCACAGTCT GACTTCCCCG CATTCCAGβC TCCTCCCTCC CTCTGCCGGC TCTGGCTCTC 1260 0 CCCAATATCC TCGCTCCCGG GACTCACTGβ CAGCCCCAGC ACCACCAGGT CTCCCGGGAA 1320
GCCACCCTCC CAGCTCTGAG GACTGCACCA TTGCTGCTCC TTAGCTGCCA AGCCCCATCC 1380
TGCCGCCCGA GGTGGCTGCC TGGAβCCCCA CTGCCCTTCT CATTTGGAAA CTAAAACTTC 1440
ATCTTCCCCA AGTGCGββGA GTACAAβGCA TββCβTAGAG GβTGCTGCCC CATGAAGCCA 1500
CAGCCCAGGC CTCCAGCTCA GCAGTGACTG TGGCCATGGT CCCCAAGACC TCTATATTTG 1560 5 CTCTTTTATT TTTATGTCTA AAATCCTGCT TAAAACTTTT CAATAAACAA βATCGTCAGG 1620
ACCAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA BHCLITERAT 1680
UREBHCBLAS TPBHCORTHO LOGUESMOUS ECXCRMYLEV SERQVLDASD FAFLLENSTS 1740
PYDYGENESD FSDSPPCPQD FSLNFDRTFL PALYSLLFLL GLLβNβAVAA VLLSQRTALS 1800
STDTFLLHLA VADVLLVLTL PLWAVDAAVQ WVFGPGLCKV AGALFNINFY AGAFLLACIS 1860 0 FDRYLSIVHA TQIYRRDPRV RVALTCIWW βLCLLFALPD FIYLSANYDQ RLNATHCQYN 1920
FPQVβRTALR VLQLVAβFLL PLLVMAYCYA HILAVLLVSR βQRRFRAMRL WWVAAFAV 1980
CWTPYHLWL VDILMDVβVL ARNCGRESHV DVAKSVTSGM GYMHCCLNPL LYAFVGVKFR 2040 EQMWMLFTRL GRSDQRGPQR QPSSSRRESS WSETTEASYL GL 5
A34 Protein sequence Gene name: CXCR3 (G protein-coupled receptor 9) ;chemokine(C-X-C) receptor 3 Unigene number: Hs.198252 Protein Accession #: P49682 0 Signal sequence: none found Pfam domains : 7tm_l [70-318] Transmembrane domains : 57-78, 92-113, 129-147, 169-190, 222-243, 257-275, 307-323 DRY box: 148-149 Cellular Localization: plasma membrane 5
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__ MVLEVSDHQV LNDAEVAALL ENFSSSYDYβ ENESDSCCTS PPCPQDFSLN FDRAFLPALY 60 0 SLLFLLβLLG NGAVAAVLLS RRTALSSTDT FLLHLAVADT LLVLTLPLWA VDAAVQWVFG 120
SGLCKVAβAL FNINFYAGAL LLACISFDRY LNIVHATQLY RRGPPARVTL TCLAVWGLCL 180
LFALPDFIFL SAHHDERLNA THCQYNFPQV GRTALRVLQL VAGFLLPLLV MAYCYAHILA 240
VLLVSRGQRR LRAMRLWW WAFALCWTP YHLWLVDIL MDLGALARNC GRESRVDVAK 300
SVTSGLβYMH CCLNPLLYAF VGVKFRERMW MLLLRLGCPN QRGLQRQPSS SRRDSSWSET 360 55 SEASYSGL
A35 DNA SEQUENCE Gene name: Differentially expressed C016 gene (clone MGC:5257) Unigene number: Hs.69517 6U Probeset Accession #: AA447522
Nucleic Acid Accession it : BC001291 Coding sequence: 44-541 (start and stop codons are underlined)
65 1 11 21 31 41 51
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GββGGCGCCG CGCGCTGACC CTCCCTGGGC ACCGCTGGGG ACGATGGCGC TGCTCGCCTT 60
GCTGCTGGTC GTGGCCCTAC CGCGGGTGTG βACAGACGCC AACCTGACTG CβAGACAACG 120
AGATCCAGAG GACTCCCAGC GAACGGACGA βββTβACAAT AGAGTGTGGT GTCATGTTTG 180
70 TGAGAGAGAA AACACTTTCG AGTGCCAGAA CCCAAGGAGG TGCAAATGGA CAGAGCCATA 240
CTGCGTTATA GCGGCCGTGA AAATATTTCC ACβTTTTTTC ATββTTGCGA AGCAGTβCTC 300
CβCTGGTTGT GCAGCGATGG AGAβACCCAA βCCAβAGGAG AAGCββTTTC TCCTGGAAGA 360
GCCCATGCCC TTCTTTTACC TCAAGTGTTG TAAAATTCGC TACTGCAATT TAGAGGGGCC 420
ACCTATCAAC TCATCAGTβT TCAAAGAATA TGCTGGGAGC ATGβGTGAGA GCTGTGGTGG 480
75 GCTGTGGCTG GCCATCCTCC TβCTGCTGGC CTCCATTGCA GCCGβCCTCA βCCTβTCTTG 540
AGCCACGGβA CTGCCACAGA CTGAGCCTTC CGGAGCATGG ACTCGCTCCA GACCGTTGTC 600
ACCTGTTGCA TTAAACTTGT TTTCTGTTGA TTACCTCTTG βTTTGACTTC CCAGGGTCTT 660
GGGATGGGAG AGTGGGGATC AGGTGCAGTT GGCTCTTAAC CCTCAAGGGT TCTTTAACTC 720
ACATTCAGAG GAAβTCCAβA TCTCCTGAGT AGTGATTTTG GTGACAAGTT TTTCTCTTTG 780
80 AAATCAAACC TTGTAACTCA TTTATTGCTG ATGGCCACTC TTTTCCTTGA CTCCCCTCTG 840
CCTCTGAGGG CTTCAβTATT GATGGGGAβG GAGβCCTAAG TACCACTCAT GGAGAGTATG 900
TGCTGAGATG CTTCCGACCT TTCAGGTGAC GCAGGAACAC TG6GGGAGTC TGAATGATTG 960
GGGTGAAGAC ATCCCTGGAG TGAAGGACTC CTCAGCATGG GGββCAGTGβ GGCACACGTT 1020
AGGGCTGCCC CCATTCCAβT GGTGGAGβCG CTGTGGATGG CTGCTTTTCC TCAACCTTTC 1080 CTACCAGATT CCAGGAGGCA GAAGATAACT AATTGTGTTG AAβAAACTTA GACTTCACCC 1140
ACCAGCTGGC ACAGGTGCAC AGATTCATAA ATTCCCACAC GTGTGTGTTC AACATCTGAA 1200
ACTTAGGCCA AGTAGAGAβC ATCAGGGTAA ATGGCGTTCA TTTCTCTGTT AAGATGCAGC 1260
CATCCATGGG GAGCTGAGAA ATCACACTCA AAβTTCCACC AAAAACAAAT ACAAGGGGAC 1320 TTCAAAAGTT CACβAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAA
A 6 Protein sequence: Gene name: Differentially expressed C016 gene (clone MGC:5257) 0 Unigene number: Hs.69517 Probeset Accession #: AA447522 Protein Accession # : AAH01291 Signal sequence: 1-17 (first underlined sequence) Transmembrane domain: 146 - 162 5 Cellular localization: plasma membrane
1 11 21 31 41 51 n\J M IALLALLLW A ILPRVWTDAN L ITARQRDPED S IQRTDEGDNR V IWCHVCEREN T IFECQNPRRC 60
KWTEPYCVIA AVKIFPRFFM VAKQCSAGCA AMERPKPEEK RFLLEEPMPF FYLKCCKIRY 120 CNLEGPPINS SVFKEYAβSM GESCGβLWLA ILLLLASIAA GLSLS
A37 DNA SEQUENCE 5 Gene name: ESTs Unigene number: Hs.293616 Probeset Accession #: AW043782 Nucleic Acid Accession #: none found
Coding sequence: 38-1075 (underlined sequence corresponds to start and stop codon) 0
1 11 21 31 41 51
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AGCAACβACβ CCGGGCAGCG GGAGCGβCGG CCGCGCCATG TGGCTGCTGG GβCCGCTGTG 60 5 CCTGCTGCTG AGCAGCGCCG CGGAGAGCCA GCTGCTCCCC GGGAACAACT TCACCAATGA 120
GTβCAACATA CCAGGCAACT TCATGTβCAβ CAATGGACGG TGCATCCCGG GCGCCTGGCA 180
GTGTGACGβG CTGCCTGACT CCTTCβACAA GAGTGATGAβ AAGGAGTGCC CCAAGGCTAA 240
GTCGAAATGT GGCCCAACCT TCTTCCCCTG TGCCAGCββC ATCCATTGCA TCATTGGTCG 300
CTTCCGGTGC AATGGGTTTG AGGACTGTCC CGATGGCAβC GATGAAGAβA ACTβCACAGC 360 0 AAACCCTCTG CTTTGCTCCA CCGCCCGCTA CCACTβCAAβ AACGGCCTCT GTATTGACAA 420
GAGCTTCATC TGCGATGGAC AGAATAACTβ TCAAGACAAC AGTGATGAGG AAAGCTGTGA 480
AAGTTCTCAA βAACCCGGCA GTGGGCAGGT GTTTGTGACT TCAGAGAACC AACTTGTGTA 540
TTACCCCAGC ATCACCTATG CCATCATCGG CAGCTCCGTC ATTTTTGTGC TGGTGGTββC 600
CCTGCTGGCA CTGGTCTTGC ACCACCAGCG GAAGCGGAAC AACCTCATGA CGCTGCCCGT 660 5 βCACCββCTG CAGCACCCTG TGCTGCTGTC CCGCCTGGTG GTCCTGGACC ACCCCCACCA 720
CTβCAACβTC ACCTACAACG TCAATAATGG CATCCAGTAT GTGβCCAGCC AGGCGGAGCA 780
GAATGCGTCG GAAGTAGGCT CCCCACCCTC CTACTCCGAG GCCTTGCTββ ACCAGAGGCC 840
TGCGTGGTAT GACCTTCCTC CACCGCCCTA CTCTTCTGAC ACGGAATCTC TGAACCAAGC 900
CGACCTGCCC CCCTACCGCT CCCGGTCCGG GAGTGCCAAC AGTGCCAGCT CCCAGGCAGC 960 0 CAGCAGCCTC CTGAGCGTGG AAGACACCAG CCACAGCCCG GGGCAGCCTG GCCCCCAGGA 1020
GGGCACTGCT GAβCCCAGGG ACTCTGAGCC CAGCCAGGβC ACTGAAGAAG TATAAβTCCC 1080
AGTTATTCCA AAGTCCATAT GββTTAATCT GCTCTGACTT GTTGCCATTC TAACAATTTG 1140
TGCTCATGGβ AAGCTCTTTA AGCACCTGTA AGGATGTCTC AAβTTACAGT TTGGGATATT 1200
AACTATCTCT GCATTCCCCT CCTCCCCCAG ACTTCAGAGA TGTTTTTCTG GCGTCTCAGT 1260 5 TGACATGATC TGTTGTGCGT CTTTTCTGTC AGβTCACTCT TCCCTTGGGA CCCGAGATCA 1320
CACCCTCATT TTTCACATTA TTCTGTTTCT GTTGGAGAGA CAGCATATAA AACAGTATTG 1380
AAATAGGCTG GGAGAGAGCA ATGTTTCTGT GCTATATTGG ATGCTCAGAA GTGCAGβAGA 1440
CGCTββACCC AATTCTCTCT GCTGGGTAGT TACCTTATAG CATTTGGGGA TTTGGGTTAG 1500
ATGATCTAAC CAGGAGGCCA TCACTGGATG GTCACCCCCC CAAAAAAATT CCATTTGAGC 1560 0 ATCAAAACCT GCTTTGCACA ATCCTATTTG ATGCCCCCAG TTCAGCAGAG TCAGTGGCCA 1620
AAGAAAACTT TGGACGTGAG TAACACCCTT CAGCAGTCGC AACGTTATTT TGGTTTTGTG 1680
AAGGACTCTG AAACCATCTA CCCTGTATAA ATTCTGGCTT TAGAAATTTG CCCAAGAATG 1740
CTCATTCTGA GAβCTTTCCT CAGCAGCATA TATCATCAGC CTCATCCTAA AATAGGCAGG 1800
GAGCCCCTCC CATGAGTTTA TCCAAGTTCT CAGCTCCTAA AATGCAGGCT GCCAAGACCC 1860 5 TACACCTGCC CTGGCTCTAC AGCCACTTAC CTGGTTTCTG GACTGTCACC CTCCCAGCTG 1920
ACCTGCCCGT AGCCAAGGAA TGAGGACCTA ACTTβAGTTG GCCCAAAGTC TGACCTββCT 1980
GTATGTCCCT GTGGCCCACA CCCAGCCTβT CTTGCTCATT CATGCAGCCT CAACACTGGC 2040
CTCCAAAGTT CCCTTAACAC TTGCAAAGTC CTTTTTACCT βTGCATTTGG ACTTGAGGAC 2100
ACTGGTTTCT ATCACAGGTG AGAGCCATβT TCAATACCTC CAGCAAGCTC TCCTGGCTCC 2160 0 CTGCACTGTG CACGCTCCTC TTCCCAAGGT CCCAATACCA GCACCTCTAG TTAGAGTTAG 2220
GGTCAGGGTC AGGCCTCTCC CAACATCCCA GTAGTTTCTC CTCTGAGACA CATGGGCAAG 2280
AGACAATTTβ GAGTCAAGAT TTTCCATTTG GATCTATTTT AAATCTTTTA GAAATGCATT 2340
TGAAACAGTβ TGTTTGTTTT TTCCCTTCTA GTTAAGGGAC TATTTATATG TGTATAGGAA 2400
AGCTGTCTCT TTTTTTGTTT TTCCTTTAAC AAGGTCCAAA GAAAβATGCA AAAGGAβATC 2460
75 ACACCCTTGC CCCGCTGAβC CCCGTGATAA CAAGTCACTC CAGACTAACC TGTGTGCCAG 2520
ACATTTGTGC ATTGTTGCAC TTTGAGGTTA TTATTTATCA AGTTCTTGAA GβAAGCAGAA 2580
AGAGββACTC CTCTCTCCCT CCGTGTATAG TCTCTATβTT TβTGCTAGTT TTTCTTTTTT 2640
TTCTCTGTβT CCAGTCAGCC ACAGGGCCCG CCTCCCTGCA GGAATAAGGG GTAAAACGTT 2700
AGGTGTTβTT TGGCAAGAAA CCACACTGAC TGATGAGGGG TAAAATGGAA CCAGGTAGAβ 2760
80 CCACTCCGGG CAGCTGTCAC CCATTCAGAA CTTCTTTCCG CAGCTGAAβA AATGTTCAGT 2820
AACCTGTTTG ACGCTAATTA AAACAGAGCC TGCAGGAAGT GβGGCTAAAG TGGCATTCAG 2880
TGATCCTGTT CTGTAGACTT TTCTTTCTTT TTTTAACCAA ATCCAAAGGA TGTTACAβAA 2940
AAβCTAβCCA CTCGTATTTT GTTTTGTTTA AAAAAAAAAA GAAAGAAAGA AAGAAAβAAA 3000 AACGGAAAGG AACCTAGCTG CCTGTATCTT TCATTTTTAA AATAGCACTT GAGTTATTTT 3060
CTGAGTAATC CAATAAAGAA CTTTTGATGA CAGCCAGAAT GTGTTAGAAC TCTGGCTGAA 3120
CATTTCATCT CCTGTGAGTC AGAAGGGCTT TATTTCTCCC TTTGATGGβG CCCCTTCTTC 3180
TTTCTGGTβC TCTGβAAGTT GTTTAGAGGA AAGAATTCTA ATTTTAATTA ATTGCGCAGT 3240 βAβTTAATCT CACTCGCTTT TCTGCTTCCA GGCATCTTAG GAAAAACAAA TCGTTTTAGT 3300
AGATAAGGGA TGCCTACTAA TGCTTTTTTA AAACAAACAG GGACATTTTT ATTATAGATT 3360
TGATTTTTTT AATGAATGTT TTTAAAAATA TATAAATAGG ACACCAAAGC GGCAGGGTTT 3420
TTTTTGGGGG GAGGGGGTTT GTTTTCCAAC TCAAGATGGC ACATTAGTGG CCAGCAATAT 3480
TTTTTAACTC ATTCCAACCA GGAAGCTTTT TTATACATTβ CCTAAATCTA CβCCAACCAG 3540
AAAATAβTCT CATCTCTTTT TTTCTCAAAT GAGATCCGTG TTTTATTTTA GCATTAAATT 3600
AGTTACACTG TGATGACTGG CCTATTACCT GACTCAGCTC CCTCTACCTT GAAATTβACA 3660
TTTTTAAAAA ATGCAACTAA βTGβTTAATA GTGTGTGACG CTCAAAGTTA ATGTAAACTG " 3720
GAAAGGTTGT GTGTCGTTGC TTTTTGTGTT TTGGTTAGGC TTGGTTTTGT TTTTTAATTT 3780
TTATACTTTC TAATAAATTT βCAGTTTCAT TCTTTCTGTT TGTGCAAAWG βWMCTAMARM 3840
AAMMAAAAAC AWYWTTGGGG GGGCTTGGGC CTCGGAAAAA GTTTTTAACA CCACTTCGGG 3900
TGGGGCGGCG ββGCCCACGT ACGTACGGCG ACCACGCGGG CCCAAACGGG ACCCCAβAAβ 3960
GAAACCCTGG CCAAGAAAAA ββTGGCGAGA ATTCTCCACA CCAGAAAAAA ACGCGCCGGG 4020
GGAAACCGCA GAβTβTTGCG TAAACCACAC CCGAAGAβAG AACTCAGAAG CACACAAGCG 4080
GGACTCAACC AGGAGGACCC AAGGGAACCC GATAGAGTAC β
A38 Protein sequence:
Gene name: ESTs
Unigene number: Hs.293616
Probeset Accession #: AW043782
Protein Accession #: none found
Signal sequence : 1-17
Transmembrane domains 169-191
LDLa domains: 28-66, 70-108, 112-149
Cellular Localization plasma membrane
11 21 31 41 51
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MWLLGPLCLL L ISSAAESQLL PGNNFTNECN IPGNFMCSNG RCIPβAWQCD GLPDCFDKSD 60 EKECPKAKSK CGPTFFPCAS GIHCIIGRFR CNGFEDCPDG SDEENCTANP LLCSTARYHC 120 KNGLCIDKSF ICDGQNNCQD NSDEESCESS QEPGSGQVFV TSENQLVYYP SITYAIIGSS 180 VIFVLWALL ALVLHHQRKR NNLMTLPVHR LQHPVLLSRL WLDHPHHCN VTYNVNNGIQ 240 YVASQAEQNA SEVGSPPSYS EALLDQRPAW YDLPPPPYSS DTESLNQADL PPYRSRSGSA 300 NSASSQAASS LLSVEDTSHS PGQPGPQEGT AEPRDSEPSQ βTEEV
A39 DNA sequence
Gene name : ESTs
Unigene number: Hs.128899
Probeset Accession #: AA983251
Nucleic Acid Accession #: AA983251 Coding sequence: 1-1749 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
A ITGCTGTCTβ GICTTCTTGAT GIAGTCCCAGT AICCCAGCACA GIAGCACAGTA CIACTCCCGGA 60
GGAAAGAAAC TTCCGTGGGA GGCTTCCATC GGTGCGCACA CCTCCCGAGG GCGAGβCAβC 120
GACCGGGAGA GGGAGAGCCG GCCGGAGGCT GCCGGGCTCC TGTGGGACCβ CGCTGCAGCC 180
GGGGAGGCGG AGAAGGGGAA CCGGGGCGAG CCGCCCβCCT GGATCCGCGC CCAGCAGCAG 240
CCGCGGCCGC CGCCAGCTGG GCAGGCTCCC GGGACTGCGG CTββGGGCGC GCAGβACCCT 300
CβCCTβCGTC CTGGACGTTC CCGGGGGAGG GTCCGGTTGC CAGTGAAACC TCCAGAGGCT 360
TCCGGACGAC AGCCCCGGGG GCCTTCTGAC TGCATCCCGA GATTTCCATC AGCGAGTGCA 420
ACTCATAAGG CAGTCCCTAA GβGGACCGGG CCACCGGCTG AGGACGGGGA TGGCTTAGGA 480
GCTCCTGGAC CTAGGGCCCG GCGTCGTCGC CTCCTGGGCG TCGCGGCAGA GGGGAGTGGC 540
CCGCGCGGAA AGCGCCGCGG GACAGTCAGT GACGAGGCCC GGGGGTCGCC GGGGCCACGA 600
CTTCTCGGAG ACCGTCCTGC GCTCTCTGGA GACGCGCTGT CCGCGCCCAG GβTGβTβCCA 660
TβTGGGGCGC TCGCCGCTCG TCCGTCTCCT CATCCTGGAA CGCCGCTTCG CTCCTGCAGC 720
TGCTGCTGGC TGCGCTGCTG GCβGCGGGGβ CβAGGβCCCA βCGGCGAGTA CTGCCACββC 780
TββCTGβACG CGCAGGGCGT CTGGCGCATC GGCTTCCAGT GTCCCGAGCG CTTCGACGGC 840
GGCGACβCCA CCATCTGCTG CGβCAβCTβC GCGTTβCGCT ACTGCTGCTC CAGCGCCGAG 900
GCGCGCCTGG ACCAβGGCβG CTGCGACAAT GACCGCCAGC AGGGCGCTGG CGAGCCTGGC 960
CGGGCGGACA AAGACGGGCC CCGACGGCTC GGCAGGGCTT CATGTCTTAG GGGTACCCAA 1020
GGAGACGGCG AGGGTGCGCC CCCACCCGTG AGGGCCTGGC AGCGGTGCTC CCCTGAAGGC 1080
TCCCCGAAAG GAAGGCAGCT CCTCAGGGCT TTCCCGββGC TGCTGCCCCG TβCCAGACGC 1140
CGCGGATTCC CATCTTCTCC ACGCGGCGGC CCCTCTCCCC TβCAGCGGCC CGCCTTGCCC 1200
ATCTACGTGC CGTTCCTCAT TGTTGGCTCC GTGTTTβTCG CCTTTATCAT CTTGGGGTCC 1260
CTG6TGGCAG CCTGTTGCTG CAGATβTCTC CββCCTAAGC AGGATCCCCA GCAGAGCCGA 1320
GCCCCAGGGG GTAACCGCTT GATGGAGACC ATCCCCATGA TCCCCAGTGC CAGCACCTCC 1380
CGGGββTCGT CCTCACGCCA GTCCAGCACA GCTGCCAGTT CCAGCTCCAG CGCCAACTCC 1440
GGGGCCCGGG CGCCCCCAAC AAGGTCACAG ACCAACTGTT GCTTGCCββA AββGACCATG 1500
AACAACGTGT ATGTCAACAT βCCCACGAAT TTCTCTGTGC TβAACTGTCA GCAGGCCACC 1560
CAGATTGTGC CACATCAAGG GCAGTATCTG CATCCCCCAT ACGTGGGGTA CACGGTGCAβ 1620
CACGACTCTG TGCCCATGAC AGCTGTGCCA CCTTTCATGG ACGGCCTGCA GCCTGGCTAC 1680
AGGCAGATTC AGTCCCCCTT CCCTCACACC AACAGTGAAC AGAAGATGTA CCCAGCGGTG 1740
ACTGTATAAC CGAGAGTCAC TββTGGGTTC CTTTACTGAA βGGAGACGAA GGCAGGGGTG 1800
GATTCTCGAG GTGGAAGTCC βCACATβTCG GTGGTATTTA TβGCACGATT CCTTTGGATG 1860
GCTTCATTTG CCCCCAGACT GTATGAAAAC ATCTCCGAAT TAGCATTTCT ββATATβTTT 1920
CATCCAβGGT ATCATTGATT TATβATGGAA AACCGGCCTC AGCTGGAGAT GACTGTGATβ 1980
TTGCTGATGG GTβTATAACA AATβCTTGAG TCCGAAβTGC CCTTGAGATA TGGTTGACGA 2040
AAGAATTTTA TAAACTGATA AATTAAGGAT TTTTATTATG TTGTTATTAT TATTTCTTTT 2100 TTGTTGTTβA CTGCACAGGA TCAAAATGCC TGTTATCTCC CTTTTACTGG GACTTTTTTT 2160
TTTTTTTTTT TTTTTTTTAA TCAGACAGGG TCTTGCTCTG TTGCCCAGGC TGβAβTβCAG 2220
TGGTGCGATC TCGGCTCACT GCAACTTCAG CCTCCTβGAT TCAGGCAACA CTCCTGGCTC 2280
AGCCTCCCAC GTGGCTGβGA TTACAGGTβC CTGCCCCCAT GGCTAATTTT TTGTATTTTT 2340
TGTAGAGATβ GGGTTTCACC ATGTTGGCTG GGCT6GTCTC ACTCTCCTGA CCTCAAGCAA 2400
TCTGCCTGTC TCAGCCTCCC AAAGTβCTGG GATTACAGGC GTGAGCCACC GCCCCCAGCC 2460
TGAGCCTTTT TTTTTTTCTA ATGCATCCAA GβTTAAGGGG AAGACGCAAA TAACAGGACT 2520
ATTCTAAAAG GAAACCTGTT TGAACTCTGT GAGATCAGTC ATCAGTCTCA GTATTCCACA 2580
GGCACACCTT AATTTCATTG TAAAAAGATA TATATATTTT GTCTATTTTT GTGCTTTTGG 2640 0 GGGCCTATTT TGTGCTTTTT TACCTTATGT AGAGATCTTA TTACAAAGTG ATTTTCTACA 2700
TTAAAAAGAG ACTGAAATAA ATTGTATAGT TACTTAACTA ATGAAGACAT TTCAGAACTC 2760
TGGGATGATT TTAATCTTGA AGTAGTAGGT GGTATAGTCA TAAAACCATT CATCCCCTTC 2820
TTGATTGTAT CTTAATTTTC TββCTTTAAβ βTGACATCTG AGAβGTAATG CATTCTTTTT 2880
TATATTGAAA TCATAAACTA TCACCCGCTG CTTCTCTGAG TTACTTTTAA TTTTβCCTTβ 2940 5 TGGTTATGβT TTGGCGTTTC CTTCTGTTTG GTTTTCAGAG CCCCATβTCT ATATAGTCCT 3000
GAGTGCAAGT AATTACTATA CTTβTAAATG AAGATCAGTA TTTCTGCCTA GATCTGATAA 3060
AAAAATTTTC TTGTCTTAGT TATAAAAATT CAAAGAAATG TGTTACAAAβ ATACTTAβTA 3120
TAGCTCCTCA GCCATAACCT GAGACTTGGG ATGAAATTTA AACCAGATAC GATTTACTTT 3180
GCAGATCATA AGGCTTTTTA TACTCTTGTT ATCAAAATGG CTTATTTTTC AGGCACTAAG 3240 0 GATTGTTAAG AGAAAAGCTT TTCAACGAAG GATTGCCTTT CTTCTCCCAC ACTGTTCTTG 3300
ATTTCCTCTC TCTTTCAGβC CTCAACAGGC ACTGTATTCA TTCCCAATGT TCCAAATTAT 3360
CAAATTCAAG TGAATTTATT TGTGTGTTCT TTACTTATAT AAAAAAAGAT AACTTTAAGβ 3420
ATGTGCAAGT ACATTTCCAA CTGCTAGCAC AACCAGTATT TTGTAATTAA ACAAATCGCT 3480
GTATGGTATG GTCTTCTACA CATTTATβTC TATAGATATC TATCGATCAT CTTTCTATTC 3540 5 TGTTTCATGA CTGAATAATβ TAAAACCAGT GTTGGCAATT GGTATCATCA ATGATACTCA 3600
TTTTTTAATA ACCAAAGGCA GGGβAAAATC ATTTTACTTA TTAATAAATA TTTTATGATG 3660 TGAAAAAAAA AAAAAAAAAA AAAAAAAAAA 0 A40 Protein sequence Gene name: ESTs Unigene number: Hs.128899 Protein Accession # : none found Signal sequence : 1-11 5 Transmembrane domains : 402-424 Cellular localization: not determined
.. 1 11 21 31 41 51 0 i i i i i i
MLSGFLMSPS TQHRAQYTPG GKKLPWEASI GAHTSRGRGS DRERESRPEA AGLLWDRAAA 60
GEAEKGNRGE PPAWIRAQQQ PRPPPAβQAP GTAAGGAQDP RLRPGRSRGR VRLPVKPPEA 120
SGRQPRGPSD CIPRFPSASA THKAVPKGTG PPAEDGDGLG APGPRARRRR LLGVAAEGSβ 180
PRGKRRGTVS DEARGSPGPR LLGDRPALSG DALSAPRWP CβALAARPSP HPGTPLRSCS 240 5 CCWLRCWRRG RGPSGEYCHG WLDAQGVWRI GFQCPERFDG GDATICCGSC ALRYCCSSAE 300
ARLDQGGCDN DRQQGAGEPG RADKDGPRRL GRASCLRGTQ GDGEGAPPPV RAWQRCSPEG 360
SPKGRQLLRA FPGLLPRARR RGFPSSPRGG PSPLQRPALP IYVPFLIVGS VFVAFIILGS 420
LVAACCCRCL RPKQDPQQSR APGGNRLMET IPMIPSASTS RGSSSRQSST AASSSSSANS 480
GARAPPTRSQ TNCCLPEGTM NNVYVNMPTN FSVLNCQQAT QIVPHQGQYL HPPYVGYTVQ 540
50 HDSVPMTAVP PFMDGLQPGY RQIQSPFPHT NSEQKMYPAV TV
A41 DNA SEQUENCE: Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H.sapiens] Unigene number: Hs.100686 DD Probeset Accession #: AA487468
Nucleic Acid Accession #: AA487468 Coding sequence: 55-555 (underlined sequences correspond to start and stop codons)
60 1 11 21 31 41 51
I I I I I I
CGGCACCAAβ AGCACTGGCC AAGTCAGCTT CTTCTGAGAG AGTCTCTAGA AGACATGATG 60
CTACACTCAG CTTTGGGTCT CTGCCTCTTA CTCGTCACAG TTTCTTCCAA CCTTGCCATT 120
GCAATAAAAA AGGAAAAGAG GCCTCCTCAG ACACTCTCAA GAGGATGGGG AGATGACATC 180
65 ACTTGGGTAC AAACTTATGA AGAAGGTCTC TTTTATGCTC AAAAAAGTAA GAAGCCATTA 240
ATβGTTATTC ATCACCTGGA GGATTGTCAA TACTCTCAAG CACTAAAGAA AGTATTTGCC 300
CAAAATGAAG AAATACAAGA AATGGCTCAG AATAAGTTCA TCATGCTAAA CCTTATGCAT 360
GAAACCACTG ATAAGAATTT ATCACCTGAT GGGCAATATG TGCCTAGAAT CATGTTTGTA 420 βACCCTTCTT TAACAβTTAG AGCTGACATA GCTGGAAGAT ACTCTAACAG ATTGTACACA 480
70 TATGAGCCTC GGGATTTACC CCTATTGATA GAAAACATGA AGAAAGCATT AAGACTTATT 540
CAGTCAGAGC TATAAGAGAT GATAGAAAAA AGCCTTCACT TCAAAGAAβT CAAATTTCAT 600
GAAGAAAACC TCTGGCACAT TGACAAATAC TAAATGTGCA AGTATATAGA TTTTGTAATA 660
TTACTATTTA GTTTTTTTAA TGTGTTTGCA ATAβTCTTAT TAAAATAAAT GTTTTTTAAA 720 TCTGAAAAAA AAAAAAAAAA AAAAAAAAA
75
A42 Protein sequence: Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H.sapiens] ._ Unigene number: Hs.100686 oU Probeset Accession #: AA487468 Protein Accession #: none found Signal sequence : 1-23 Transmembrane domains : none found Cellular Localization: secreted 1 11 21 31 41 51
I I I I I I
MMLHSALGLC LLLVTVSSNL AIAIKKEKRP PQTLSRGWGD DITWVQTYEE βLFYAQKSKK 60 PLMVIHHLED CQYSQALKKV FAQNEEIQEM AQNKFIMLNL MHETTDKNLS PDGQYVPRIM 120 FVDPSLTVRA DIAGRYSNRL YTYEPRDLPL LIENMKKALR LIQSEL
A43 DNA SEQUENCE Gene name : ATPase, Ca++ transporting, type 2C, member 1 Unigene number: Hs.106778 Probeset Accession #: N51919
Nucleic Acid Accession #: AF189723
Coding sequence: 1-2712 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
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ATGATTCCTG TATTβACATC AAAAAAAGCA AGTGAATTAC CAβTCAGTGA AGTTGCAAGC 60
ATTCTCCAAG CTGATCTTCA GAATGGTCTA AACAAATGTG AAGTTAGTCA TAGβCCAβCC 120
TTTCATGGCT GGAATGAGTT TGATATTAGT GAAGATGAGC CACTGTGGAA GAAGTATATT 180
TCTCAGTTTA AAAATCCCCT TATTATβCTG CTTCTGβCTT CTGCAGTCAT CAGTGTTTTA 240
ATGCATCAGT TTGATGATGC CGTCAGTATC ACTGTGGCAA TACTTATCGT TGTTACAGTT 300
GCCTTTGTTC AGGAATATCG TTCAGAAAAA TCTCTTGAAG AATTGAGTAA ACTTGTGCCA 360
CCAGAATGCC ATTβTGTGCG TGAAGGAAAA TTGGAGCATA CACTTGCCCG AGACTTβGTT 420
CCAGGTGATA CAGTTTGCCT TTCTGTTGGG GATAGAGTTC CTGCT6ACTT ACGCTTGTTT 480
GAGGCTGTβG ATCTTTCCAT TGATGAGTCC AGCTTGACAG GTGAβACAAC GCCTTGTTCT 540
AAββTGACAG CTCCTCAGCC AβCTGCAACT AATGGAGATC TTGCATCGAG AAGTAACATT 600
GCCTTTATGG GAACACTGGT CAβATGTGGC AAAGCAAAGG GTβTTGTCAT TGGAACA6GA 660
GAAAATTCTG AATTTGGββA GGTTTTTAAA ATGATGCAAG CAGAAGAGGC ACCAAAAACC 720
CCTCTGCAGA AGAGCATGβA CCTCTTAGGA AAACAACTTT CCTTTTACTC CTTTGGTATA 780
ATAββAATCA TCATGTTGβT TGGCTGGTTA CTGGGAAAAG ATATCCTGGA AATGTTTACT 840
ATTAGTGTAA GTTTGGCTGT AGCAGCAATT CCTGAAGβTC TCCCCATTβT GGTCACAGTG 900
ACGCTAGCTC TT6GTGTTAT GAGAATGGTG AAGAAAAGββ CCATTβTGAA AAAGCTGCCT 960
ATTGTTGAAA CTCTGGGCTG CTGTAATGTG ATTTGTTCAG ATAAAACTGG AACACTGACG 1020
AAGAATGAAA TβACTGTTAC TCACATATTT ACTTCAGATG GTCTGCATGC TGAGGTTACT 1080
GGAGTTGβCT ATAATCAATT TGGGGAAGTG ATTGTTGATβ GTGATGTTGT TCATGGATTC 1140
TATAACCCAG CTGTTAGCAG AATTGTTGAG βCGGGCTGTG TGTGCAATGA TGCTGTAATT 1200
AGAAACAATA CTCTAATGGG GAAGCCAACA GAAGGGGCCT TAATTGCTCT TGCAATGAAβ 1260
ATβGGTCTTβ ATGGACTTCA ACAAGACTAC ATCAGAAAAG CTGAATACCC TTTTAβCTCT 1320
GAGCAAAAGT ββATGGCTGT TAAGTGTβTA CACCGAACAC AβCAGGACAG ACCAβAβATT 1380
TβTTTTATGA AAGGTGCTTA CGAACAAGTA ATTAAβTACT GTACTACATA CCAGAGCAAA 1440
GGGCAGACCT TGACACTTAC TCAGCAGCAG AGAGATGTGT ACCAACAAGA GAAGβCACGC 1500
ATGGβCTCAG CGGGACTCAβ AGTTCTTGCT TTGGCTTCTG GTCCTGAACT GGGACAGCTG 1560
ACATTTCTTG GCTTGGTGGG AATCATTGAT CCACCTAGAA CTGGTGTGAA AGAAGCTβTT 1620
ACAACACTCA TTβCCTCAGG AGTATCAATA AAAATGATTA CTGGAGATTC ACAGGAGACT 1680
GCAGTTGCAA TCGCCAGTCG TCTGGGATTβ TATTCCAAAA CTTCCCAβTC AGTCTCAGGA 1740
GAAGAAATAG ATGCAATGGA TGTTCAGCAG CTTTCACAAA TAGTACCAAA GGTTGCAGTA 1800
TTTTACAGAG CTAGCCCAAG GCACAAGATG AAAATTATTA AGTCGCTACA GAAGAACGGT 1860
TCAGTTGTAG CCATGACAGβ AGATGGAGTA AATGATβCAG TTGCTCTGAA GGCTGCAGAC 1920
ATTGGAGTTG CGATGGGCCA GACTGGTACA GATGTTTGCA AAGAGGCAGC AGACATGATC 1980
CTAGTGGATG ATGATTTTCA AACCATAATG TCTGCAATCG AAGAGGGTAA AGGGATTTAT 2040
AATAACATTA AAAATTTCGT TAGATTCCAβ CTGAGCACGA GTATAGCAGC ATTAACTTTA 2100
ATCTCATTGG CTACATTAAT GAACTTTCCT AATCCTCTCA ATGCCATGCA GATTTTGTGG 2160
ATCAATATTA TTATGGATGβ ACCCCCAGCT CAGAβCCTTG GAGTAGAACC AGTGGATAAA 2220
GATGTCATTC GTAAACCTCC TCGCAACTGG AAAGACAGCA TTTTGACTAA AAACTTGATA 2280
CTTAAAATAC TTGTTTCATC AATAATCATT GTTTGTGGGA CTTTGTTTGT CTTCTGGCβT 2340
GAGCTACβAG ACAATGTGAT TACACCTCGA GACACAACAA TGACCTTCAC ATGCTTTGTG 2400
TTTTTTGACA TGTTCAATGC ACTAAGTTCC AGATCCCAβA CCAAGTCTGT GTTTGAGATT 2460
GGACTCTGCA GTAATAGAAT GTTTTGCTAT βCAGTTCTTG βATCCATCAT GGGACAATTA 2520
CTAGTTATTT ACTTTCCTCC βCTTCAGAAG βTTTTTCAβA CTGAGAGCCT AAGCATACTG 2580
GATCTGTTGT TTCTTTTGGG TCTCACCTCA TCAGTGTGCA TAGTGGCAGA AATTATAAAG 2640
AAGGTTGAAA GGAGCAGββA AAAGATCCAG AAGCATGTTA GTTCGACATC ATCATCTTTT 2700
CTTGAAGTAT GA
A44 Protein sequence:
Gene name: ATPase, Ca++ transporting type 2C, member 1
Unigene number: Hs .106778 Probeset Accession # : N51919
Protein Accession # : AAF27813
Signal sequence: none found
Transmembrane domains : 60-82 , 86-108 , 252-274 282-304, 757-779, 827-849, 856-878
Pfam domains : Cation ATPase N [6-83] E1-E2 ATPase [89-324] , Hydrolase [328-649] , Cation ATPase C [744-889]
Cellular Localization: not determined
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I I I I
MIPVLTSKKA S 1ELPVSEVAS ILQADLQNGL NKCEVSHRRA FHGWNEFDIS EDEPLWKKYI 60 SQFKNPLIML LLASAVISVL MHQFDDAVSI TVAILIWTV AFVQEYRSEK SLEELSKLVP 120 PECHCVREGK LEHTLARDLV PGDTVCLSVG DRVPADLRLF EAVDLSIDES SLTGETTPCS 180 KVTAPQPAAT NGDLASRSNI AFMGTLVRCG KAKβWIβTG ENSEFGEVFK MMQAEEAPKT 240 PLQKSMDLLG KQLSFYSFGI IGIIMLVGWL LGKDILEMFT ISVSLAVAAI PEGLPIWTV 300 TLALGVMRMV KKRAIVKKLP IVETLGCCNV ICSDKTCTLT KNEMTVTHIF TSDGLHAEVT 360
GVGYNQFGEV IVDGDWHGF YNPAVSRIVE AGCVCNDAVI RNNTLMGKPT EGALIALAMK 420
MGLDGLQQDY IRKAEYPFSS EQKWMAVKCV HRTQQDRPEI CFMKGAYEQV IKYCTTYQSK 480
GQTLTLTQQQ RDVYQQEKAR MGSAGLRVLA LASGPELGQL TFLGLVGIID PPRTGVKEAV 540
TTLIASGVSI KMITGDSQET AVAIASRLGL YSKTSQSVSG EEIDAMDVQQ LSQIVPKVAV 600
FYRASPRHKM KIIKSLQKNG SWAMTGDGV NDAVALKAAD IGVAMβQTGT DVCKEAADMI 660
LVDDDFQTIM SAIEEGKGIY NNIKNFVRFQ LSTSIAALTL ISLATLMNFP NPLNAMQI W 720
INIIMDGPPA QSLGVEPVDK DVIRKPPRNW KDSILTKNLI LKILVSSIII VCβTLFVFWR 780
ELRDNVITPR DTTMTFTCFV FFDMFNALSS RSQTKSVFEI GLCSNRMFCY AVLGSIMGQL 840
LVIYFPPLQK VFQTESLSIL DLLFLLGLTS SVCIVAEIIK KVERSREKIQ KHVSSTSSSF 900 LEV
A45 DNA sequence
Gene name: ESTs Unigene number: HS.157601 Probeset Accession #: W07459 Nucleic Acid Accession # : AC005383 Coding Sequence: 328-2751 (underlined sequences correspond to start and stop codons)
21 31 41 51
G IACAGTGTTC GICGGCTGCAC CIGCTCGGAGG CITGGGTGACC CIGCGTAGAAG TIGAAGTACTT 60 TTTTATTTGC AGACCTGGGC CGATGCCβCT TTAAAAAACG CGAGGGGCTC TATGCACCTC 120 CCTGGCGGTA GTTCCTCCGA CCTCAGCCGG GTCGGGTCGT GCCGCCCTCT CCCAGGAGAβ 180 ACAAACAGGT GTCCCACβTβ GCAGCCGCGC CCCββGCGCC CCTCCTGTGA TCCCGTAGCG 240 CCCCCTGGCC CGAGCCGCGC CCGGGTCTGT GAGTAGAGCC βCCCβGGCAC CGAGCGCTGG 300 TCGCCGCTCT CCTTCCGTTA TATCAACATβ CCCCCTTTCC TGTTGCTGGA GGCCGTCTGT 360 GTTTTCCTGT TTTCCAGAGT GCCCCCATCT CTCCCTCTCC AGGAAGTCCA TGTAAGCAAA 420 GAAACCATCG GGAAGATTTC AβCTGCCAGC AAAATGATGT GGTGCTCGGC TGCAGTGGAC 480 ATCATGTTTC TGTTAGATGG GTCTAACAGC GTCCGGAAAG GGAGCTTTGA AAGGTCCAAG 540 CACTTTβCCA TCACAGTCTG TGACGGTCTG GACATCAGCC CCGAGAGGGT CAGAGTGGGA 600 GCATTCCAGT TCAGTTCCAC TCCTCATCTG GAATTCCCCT TGGATTCATT TTCAACCCAA 660 CAGGAAGTGA AGGCAAGAAT CAAGAGGATG GTTTTCAAAG GAGGGCGCAC GGAGACGGAA 720 CTTGCTCTGA AATACCTTCT GCACAGAGGG TTGCCTGGAG GCAGAAATGC TTCTGTGCCC 780 CAGATCCTCA TCATCGTCAC TGATGGGAAG TCCCAGGGGG ATGTGGCACT GCCATCCAAG 840 CAGCTGAAGG AAAGGGGTGT CACTGTGTTT GCTGTGGGGG TCAGGTTTCC CAGGTGGGAG 900 GAGCTGCATG CACTGGCCAG CGAGCCTAGA GGGCAGCACG TGCTβTTGGC TGAGCAGGTG 960 GAGGATGCCA CCAACβGCCT CTTCAGCACC CTCAGCAGCT CGGCCATCTG CTCCAGCGCC 1020 ACGCCAGACT GCAGGGTCGA GGCTCACCCC TGTGAGCACA GGACGCTGGA GATGGTCCGG 1080 βAGTTCGCTG GCAATGCCCC ATGCTGGAGA GGATCGCGGC GGACCCTTGC GGTGCTGGCT 1140 GCACACTGTC CCTTCTACAG CTGGAAGAGA βTGTTCCTAA CCCACCCTGC CACCTGCTAC 1200 AGGACCACCT GCCCAGGCCC CTGTGACTCG CAGCCCTGCC AGAATGGAGG CACATβTβTT 1260 CCAβAAβGAC TGGACGGCTA CCAGTβCCTC TGCCCGCTGG CCTTTGGAGG GGAGGCTAAC 1320 TGTβCCCTGA AGCTGAGCCT GGAATGCAGβ GTCGACCTCC TCTTCCTGCT βGACAGCTCT 1380 GCGGGCACCA CTCTGGACGG CTTCCTGCGG GCCAAAGTCT TCGTGAAGCG GTTTGTGCGG 1440 GCCGTGCTGA GCGAGGACTC TCGGGCCCGA GTGGGTGTGG CCACATACAG CAGGGAGCTG 1500 CTGGTGGCGG TGCCTGTGGG GGAGTACCAβ GATGTGCCTG ACCTGGTCTG GAGCCTCGAT 1560 GGCATTCCCT TCCGTGGTGG CCCCACCCTG ACGGGCAGTG CCTTGCGGCA GGCGGCAGAG 1620 CGTGGCTTCG GGAβCGCCAC CAGGACAGGC CAGGACCGGC CACGTAGAβT GGTGGTTTTG 1680 CTCACTGAGT CACACTCCGA GGATGAGGTT GC6GGCCCAG CGCGTCACGC AAGGGCβCGA 1740 GAGCTGCTCC TGCTGGGTGT AGGCAGTGAG GCCGTGCGGG CAGAGCTGGA GGAGATCACA 1800 GGCAGCCCAA AGCATGTGAT GGTCTACTCG GATCCTCAGG ATCTβTTCAA CCAAATCCCT 1860 GAGCTGCAGG GGAAGCTGTG CAGCCGGCAG CGGCCAGGGT GCCGGACACA AGCCCTGGAC 1920 CTCGTCTTCA TGTTGGACAC CTCTGCCTCA GTAGGGCCCG AGAATTTTGC TCAGATGCAG 1980 AGCTTTGTGA GAAGCTGTGC CCTCCAGTTT GAGGTGAACC CTGACGTGAC ACAGGTCGGC 2040 CTGGTGGTGT ATGGCAGCCA GGTGCAGACT GCCTTCGGGC TGGACACCAA ACCCACCCGG 2100 GCTGCGATGC TGCGGGCCAT TAGCCAGGCC CCCTACCTAG GTGGGGTGGG CTCAGCCGGC 2160 ACCGCCCTβC TβCACATCTA TGACAAAGTβ ATGACCGTCC AGAGGGGTGC CCGGCCTGGT 2220 GTCCCCAAAG CTGTGGTβGT GCTCACAGGC GGGAGAGGCβ CAGAGGATGC AGCCGTTCCT 2280 GCCCAGAAGC TGAGGAACAA TGGCATCTCT GTCTTGGTCG TGGGCGTGGG GCCTGTCCTA 2340 AGTGAGGGTC TGCGGAββCT TGCAGGTCCC CGGGATTCCC TGATCCACGT GGCAGCTTAC 2400 GCCβACCTGC GGTACCACCA GGACGTGCTC ATTGAGTGGC TGTGTGGAGA AGCCAAGCAG 2460 CCAGTCAACC TCTGCAAACC CAGCCCGTGC ATGAATGAGG GCAGCTGCGT CCTGCAGAAT 2520 GGGAGCTACC GCTGCAAGTG TCGGGATGGC TGGGAGGGCC CCCACTGCGA GAACCGTGAG 2580 TGGAGCTCTT GCTCTGTATG TGTGAGCCAG GGATβGATTC TTGAGACGCC CCTGAGGCAC 2640 ATβGCTCCCG TGCAβGAGGG CAGCAGCCGT ACCCCTCCCA GCAACTACAβ AGAAGGCCTG 2700 GGCACTGAAA TGGTGCCTAC CTTCTGGAAT GTCTGTGCCC CAGGTCCTTA GAATGTCTGC 2760 TTCCCGCCGT GGCCAGGACC ACTATTCTCA CTGAGGGAGG AGGATGTCCC AACTGCAGCC 2820 ATGCTGCTTA GAGACAAGAA AGCAGCTGAT GTCACCCACA AACGATGTTG TTGAAAAGTT 2880 TTGATGTGTA AGTAAATACC CACTTTCTβT ACCTβCTGTG CCTTGTTβAG GCTATGTCAT 2940 CTGCCACCTT TCCCTTGAGG ATAAACAAGG GGTCCTGAAG ACTTAAATTT AGCGGCCTGA 3000 CGTTCCTTTG CACACAATCA ATGCTCGCCA GAATGTTGTT GACACAGTAA TGCCCAGCAG 3060 AGGCCTTTAC TAGAGCATCC TTTGGACGGC GAAGGCCACβ GCCTTTCAAG ATGGAAAGCA 3120 GCAGCTTTTC CACTTCCCCA GAGACATTCT GGATGCATTT GCATTGAGTC TGAAAGGGGG 3180 CTTGAGGGAC GTTTGTGACT TCTTGGCGAC TGCCTTTTGT GTGTGGAAGA GACTTGGAAA 3240 GβTCTCAGAC TCAATGTGAC CAATTAACCA GCTTGGTTGA TGATGGGGGA GGGGCTCAGT 3300 TGTGCATGGG CCCAGGTCTG βAGGGCCACG TAAAATCGTT CTGAGTCGTG AGCAGTGTCC 3360 ACCTTGAAGG TCTTC
A46 Protein sequence Gene name: Unigene number: Hs.157601
Protein Accession #: none found
Signal sequence: 1-17
Transmembrane domains: none found
VCW domains: 49-223; 341-518; 529-706
EGF domains: 298-333; 715-748
Cellular Localization: secreted
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I I I I I I
MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN 60
SVGKGSFERS KHFAITVCDG LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR 120
MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180
FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240
PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300
SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL 360
RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT 420
LTGSALRQAA ERGFGSATRT GQDRPRRVW LLTESHSEDE VAGPARHARA RELLLLGVGS 480
EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540
SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600
APYLGGVGSA GTALLHIYDK VMTVQRGARP GVPKAWLT GGRβAEDAAV PAQKLRNNGI 660
SVLWGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK QPVNLCKPSP 720
CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR EWSSCSVCVS QGWILETPLR HMAPVQEGSS 780 RTPPSNYREG LβTEMVPTFW NVCAPβP
COLON
A47 DNA SEQUENCE: Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H. sapiens] Unigene number: Hs.100686 Probeset Accession #: AA487468 Nucleic Acid Accession #: AA487468 Coding sequence: 55-555 (underlined sequences correspond to start and stop codons)
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CGGCACCAAG AGCACTGGCC AAGTCAGCTT CTTCTGAGAG AGTCTCTAGA AGACATGATβ 60
CTACACTCAG CTTTGGGTCT CTGCCTCTTA CTCβTCACAG TTTCTTCCAA CCTTGCCATT 120
GCAATAAAAA AGGAAAAGAG βCCTCCTCAG ACACTCTCAA GAGGATGGGG AGATGACATC 180
ACTTGGGTAC AAACTTATGA AGAAGGTCTC TTTTATGCTC AAAAAAGTAA GAAGCCATTA 240
ATGGTTATTC ATCACCTGGA GGATTGTCAA TACTCTCAAG CACTAAAGAA AGTATTTGCC 300
CAAAATGAAG AAATACAAGA AATGGCTCAG AATAAGTTCA TCATGCTAAA CCTTATGCAT 360
GAAACCACTG ATAAGAATTT ATCACCTGAT GGGCAATATG TGCCTAGAAT CATGTTTGTA 420
GACCCTTCTT TAACAGTTAG AGCTGACATA GCTGGAAGAT ACTCTAACAG ATTGTACACA 480
TATGAGCCTC GGGATTTACC CCTATTGATA GAAAACATGA AGAAAGCATT AAGACTTATT 540
CAGTCAβAGC TATAAGAGAT GATAGAAAAA AGCCTTCACT TCAAAGAAGT CAAATTTCAT 600
GAAGAAAACC TCTGGCACAT TGACAAATAC TAAATGTGCA AGTATATAβA TTTTGTAATA 660
TTACTATTTA GTTTTTTTAA TGTGTTTGCA ATAGTCTTAT TAAAATAAAT GTTTTTTAAA 720 TCTGAAAAAA AAAAAAAAAA AAAAAAAAA
A48 Protein sequence:
Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H. sapiens]
Unigene number: Hs.100686
Probeset Accession #: AA487468
Protein Accession (t: none found Signal sequence: 1-23
Transmembrane domains: none found
Cellular Localization: secreted
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I I I I I I
MMLHSALGLC LLLVTVSSNL AIAIKKEKRP PQTLSRGWGD DITWVQTYEE GLFYAQKSKK 60 PLMVIHHLED CQYSQALKKV FAQNEEIQEM AQNKFIMLNL MHETTDKNLS PDGQYVPRIM 120 FVDPSLTVRA DIAβRYSNRL YTYEPRDLPL LIENMKKALR LIQSEL
A49 DNA SEQUENCE βene name: β protein-coupled receptor 56
Unigene number: Hs.6527
Probeset Accession #: AA478599
Nucleic Acid Accession #: NM_005682
Coding seguence: 163-2244 (underlined sequences correspond to start and stop codons)
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I I I I I I
CGβCAGCAGβ GTCTCGCTCT GTCACACAGG CTGGAGTGCA GTGGTGTGAT CTTGGCTCAT 60 CGTAACCTCC ACCTCCCCGG TTCAAGTGAT TCTCATGCCT CAβCCTCCCG AGTAGCTGGG 120 ATTACAGGTG GTGACTTCCA AGAGT6ACTC CβTCβGAGGA AAATGACTCC CCAGTCGCTG 180 CTCCAβACβA CACTGTTCCT GCTGAGTCTG CTCTTCCTGG TCCAAGGTGC CCACGGCACG 240
GGCCACAGββ AAGACTTTCG CTTCTβCAGC CAGCGGAACC AGACACACAG GAGCAGCCTC 300
CACTACAAAC CCACACCAGA CCTGCGCATC TCCATCGAGA ACTCCGAAGA GGCCCTCACA 360
GTCCATGCCC CTTTCCCTGC AβCCCACCCT GCTTCCCGAT CCTTCCCTGA CCCCAGGGGC 420
CTCTACCACT TCTGCCTCTA CTGGAACCGA CATGCTβGGA GATTACATCT TCTCTATGβC 480
AAGCβTβACT TCTTGCTGAG TGACAAAGCC TCTAGCCTCC TCTGCTTCCA GCACCAGGAG 540
GAGAGCCTββ CTCAGGGCCC CCCGCTGTTA GCCACTTCTG TCACCTCCTG GTGGAGCCCT 600
CAGAACATCA GCCTβCCCAG TGCCGCCAGC TTCACCTTCT CCTTCCACAG TCCTCCCCAC 660
ACGGCCGCTC ACAATGCCTC GGTGGACATG TGCGAGCTCA AAAGββACCT CCAGCTGCTC 720
AGCCAGTTCC TGAAGCATCC CCAGAAGGCC TCAAβGAGGC CCTCβGCTGC CCCCGCCAGC 780
CAGCAGTTGC AGAGCCTGGA GTCGAAACTG ACCTCTGTβA GATTCATGGG GGACATGGTβ 840
TCCTTCGAGG AGβACCGGAT CAACGCCACG GTATGGAAGC TCCAGCCCAC AGCCGGCCTC 900
CAGGACCTGC ACATCCACTC CCGGCAGGAG GAGβAβCAGA GCGAGATCAT GGAGTACTCβ 960
GTGCTGCTGC CTCGAACACT CTTCCAGAGG ACGAAAGβCC GGAβCβGGGA GGCTGAβAAβ 1020
AGACTCCTCC TCGTGGACTT CAGCAβCCAA GCCCTGTTCC AββACAAGAA TTCCAβCCAA 1080
GTCCTGGGTG AGAAGGTCTT GβββATTGTG GTACAGAACA CCAAAβTAβC CAACCTCACβ 1140
GAGCCCGTGG TGCTCACTTT CCAGCACCAG CTACAGCCGA AGAATGTβAC TCTGCAATGT 1200
GTGTTCTGGG TTGAAGACCC CACATTGAGC AβCCCGGGGC ATTGGAGCAG TβCTGGGTGT 1260
GAGACCGTCA GGAGAGAAAC CCAAACATCC TGCTTCTGCA ACCACTTGAC CTACTTTGCA 1320
GTGCTGATGG TCTCCTCGGT ββAββTβGAC GCCβTβCACA AGCACTACCT βAβCCTCCTC 1380
TCCTACGTGG GCTβTβTCGT CTCTGCCCTG GCCTGCCTTG TCACCATTGC CGCCTACCTC 1440
TGCTCCAGGG TGCCCCTβCC GTGCAβGAGG AAACCTCCGG ACTACACCAT CAAGGTβCAC 1500
ATGAACCTGC TGCTGGCCGT CTTCCTβCTβ GACACGAGCT TCCTGCTCAG CGAGCCGGTG 1560
GCCCTGACAβ GCTCTGAGGC TGGCTGCCβA GCCAGTGCCA TCTTCCTGCA CTTCTCCCTG 1620
CTCACCTGCC TTTCCTGGAT GGGCCTCGAG GββTACAACC TCTACCGACT CβTGGTGGAG 1680
GTCTTTGGCA CCTATGTCCC TGGCTACCTA CTCAAGCTGA GCGCCATGGG CTGGGGCTTC 1740
CCCATCTTTC TGGTGACGCT GGTβGCCCTG GTGGATGTββ ACAACTATGG CCCCATCATC 1800
TTGGCTGTGC ATAGGACTCC AGAGββCβTC ATCTACCCTT CCATGTGCTG GATCCGGGAC 1860
TCCCTβGTCA 6CTACATCAC CAACCTGGGC CTCTTCAβCC TGGTGTTTCT GTTCAACATG 1920
GCCATβCTAG CCACCATGGT GGTGCAβATC CTGCGGCTGC GCCCCCACAC CCAAAAβTββ 1980
TCACATGTGC TGACACTGCT GGGCCTCAGC CTGGTCCTTG CCCTGCCCTG GGCCTTGATC 2040
TTCTTCTCCT TTGCTTCTGG CACCTTCCAG CTTGTCGTCC TCTACCTTTT CAGCATCATC 2100
ACCTCCTTCC AAGGCTTCCT CATCTTCATC TGGTACTGGT CCATGCββCT GCAGGCCCGG 2160
GGTGGCCCCT CCCCTCTGAA GAGCAACTCA GACTGCGCCA GGCTCCCCAT CAGCTCGGGC 2220
AGCACCTCGT CCAGCCGCAT CTAGGCCTCC AGCCCACCTG CCCATGTGAT GAAGCAGAGA 2280
TGCGGCCTCG TCGCACACTG CCTGTGGCCC CCGAGCCAGG CCCAGCCCCA GGCCAGTCAG 2340
CCGCAGACTT TGGAAAGCCC AACGACCATG GAβAGATGGG CCGTTGCCAT ββTGGACGGA 2400
CTCCCβββGC TGGGGCTTTT GAATTGGCCT TGβGGACTAC TCGGCTCTCA CTCAGCTCCC 2460
ACββGACTCA GAAGTGCGCC GCCATGCTβC CTAGGGTACT GTCCCCACAT CTGTCCCAAC 2520
CCAβCTGGAG GCCTGGTCTC TCCTTACAAC CCCTGGGCCC AβCCTCATTG CTGGGCβCCA 2580
GGCCTTGGAT CTTGAGGGTC TGGCACATCC TTAATCCTGT GCCCCTGCCT GGGACAGAAA 2640
TGTβGCTCCA GTTGCTCTGT CTCTCGT6GT CACCCTGAGG GCACTCTGCA TCCTCTGTCA 2700
TTTTAACCTC AGGTβGCACC CAGββCβAAT GGGGCCCAGG GCAGACCTTC AGGGCCAGAβ 2760
CCCTGGCGGA GGAGAGGCCC TTTGCCAGGA GCACAGCAGC AβCTCβCCTA CCTCTβAβCC 2820 G
A50 Protein sequence βene name: G protein-coupled receptor 56 Unigene number: Hs.6527 Protein Accession #: NM_005682.1 Signal sequence: 1-26 GPS domain: 342-394 Pfam domain: 7tm_2 [400-665] Transmembrane domains : 410-432 , 446-468 , 482-504 , 517-539, 575-597 , 608-630 , 638-659 Cellular Localization: plasma membrane
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I I I I I I
MTPQSLLQTT LFLLSLLFLV QGAHGRβHRE DFRFCSQRNQ THRSSLHYKP TPDLRISIEN 60 SEEALTVHAP FPAAHPASRS FPDPRβLYHF CLYWNRHAGR LHLLYGKRDF LLSDKASSLL 120 CFQHQEESLA QGPPLLATSV TSWWSPQNIS LPSAASFTFS FHSPPHTAAH NASVDMCELK 180 RDLQLLSQFL KHPQKASRRP SAAPASQQLQ SLESKLTSVR FMGDMVSFEE DRINATVWKL 240 QPTAGLQDLH IHSRQEEEQS EIMEYSVLLP RTLFQRTKGR SβEAEKRLLL VDFSSQALFQ 300 DKNSSQVLβE KVLGIWQNT KVANLTEPW LTFQHQLQPK NVTLQCVFWV EDPTLSSPGH 360 WSSAGCETVR RETQTSCFCN HLTYFAVLMV SSVEVDAVHK HYLSLLSYVG CWSALACLV 420 TIAAYLCSRV PLPCRRKPRD YTIKVHMNLL LAVFLLDTSF LLSEPVALTG SEAGCRASAI 480 FLHFSLLTCL SWMGLEGYNL YRLWEVFβT YVPGYLLKLS AMGWβFPIFL VTLVALVDVD 540 NYGPIILAVH RTPEβVIYPS MCWIRDSLVS YITNLGLFSL VFLFNMAMLA TMWQILRLR 600 PHTQKWSHVL TLLGLSLVLG LPWALIFFSF ASGTFQLWL YLFSIITSFQ GFLIFIWYWS 660 MRLQARGGPS PLKSNSDCAR LPISSβSTSS SRI
A51 PNA SEQUENCE Gene name: Hypothetical protein FLJ20063 Unigene number: Hs.5940 Probeset Accession #: AA053660 Nucleic Acid Accession #: AA053660 Coding sequence: 218-1360 (underlined sequences correspond to start and stop codons)
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CCCCCATGAC TTTGTACAGC TACTTCACTG CTTCCCCCCA ATTAGTACAC ATAGTTCCTC CACAATTCCT ACACCTCCTC CCCCCATAAT CAGTACACAT AGTTCCTCCA CAATTCCTAT 120
ACCTACTGCT CCAGACAGTG AGTCAACCAC AAATGTAAAT TCATTAβCTA CCTCTGACAT 180
AATCACCGCT TCATCTCCAA ATβATGGATT AATCACAATG GTTCCTTCTG AAACACAAAG 240
TAACAATGAA ATGTCCCCCA CCACAGAAGA CAATCAATCA TCAGββCCTC CCACTGGCAC 300
CGCTTTATTG GAGACCAGCA CCCTAAACAG CACAGGTCCC AGCAATCCTT GCCAAβATGA 360
TCCCTGTGCA GATAATTCGT TATGTGTTAA GCTGCATAAT ACAAGTTTTT GCCTβTGTTT 420
AGAAGGGTAT TACTACAACT CTTCTACATG TAAGAAAGGA AAGGTATTCC CTGGGAAGAT 480
TTCAGTGACA GTATCAGAAA CATTTGACCC AGAAGAGAAA CATTCCATGG CCTATCAAGA 540
CTTGCATAGT GAAATTACTA GCTTGTTTAA AGATGTATTT GGCACATCTG TTTATGGACA 600
GACTGTAATT CTTACTGTAA GCACATCTCT GTCACCAAGA TCTGAAATGC GTGCTGATGA 660
CAAGTTTGTT GATGTAACAA TAGTAACAAT TTTGGCAGAA ACCACAAGTG ACAATGAGAA 720
GACTGTGACT GAGAAAATTA ATAAAGCAAT TAGAAGTAGC TCAAGCAACT TTCTAAACTA 780
TGATTTGACC CTTCββTβTβ ATTATTATGG CTGTAACCAG ACTGCβGATG ACTGCCTCAA 840
TGGTTTAGCA TGCGATTβCA AATCTGACCT GCAAAGGCCT AACCCACAβA GCCCTTTCTG 900
CGTTGCTTCC AGTCTCAAGT GTCCTGATGC CTGCAACGCA CAGCACAAGC AATβCTTAAT 960
AAAGAA6AGT 6GTGGGGCCC CTGAGTGTGC GTGCGTGCCC GGCTACCAGG AAGATGCTAA 1020
TGGGAACTGC CAAAAGTGTG CATTTGGCTA CAGTGGACTC GACTGTAAGG ACAAATTTCA 1080
GCTGATCCTC ACTATTGTGβ GCACCATCGC TGGCATTGTC ATTCTCAGCA TGATAATTGC 1140
ATTGATTGTC ACAβCAAβAT CAAATAACAA AACGAAGCAT ATTGAAGAAG AGAACTTGAT 1200
TGACGAAGAC TTTCAAAATC TAAAACTGCG GTCGACAGGC TTCACCAATC TTβGAGCAGA 1260
AGGGAGCGTC TTTCCTAACβ TCAβGATAAC GGCCTCCAGA GACAGCCAGA TGCAAAATCC 1320
CTATTCAAGA CACAGCAGCA TGCCCCGCCC TGACTATTAG AATCATAAGA ATGT6GAACC 1380
CGCCATGGCC CCCAACCAAT GTACAAGCTA TTATTTAGAG TGTTTAGAAA GACTβATGGA 1440
GAAβTGAGCA CCAGTAAAGA TCTGGCCTCC GGGGTTTTTC TTCCATCTGA CATCTGCCAG 1500
CCTCTCTGAA TGGAAGTTGT GAATGTTTGC AACGAATCCA GCTCACTTGC TAAATAAGAA 1560
TCTATGACAT TAAATGTAGT AGATGCTATT AGCGCTTGTC AGAGAGGTGG TTTTCTTCAA 1620
TCAGTACAAA GTACTβAGAC AATGGTTAGβ GTTGTTTTCT TAATTCTTTT CCTGGTAGGG 1680
CAACAAGAAC CATTTCCAAT CTAGAGGAAA GCTCCCCAGC ATTGCTTGCT CCTGββCAAA 1740
CATTGCTCTT GAGTTAAGTG ACCTAATTCC CCTGGGAGAC ATACGCATCA ACTGTGGAGG 1800
TCCGAGGGGA TGAGAAGGGA TACCCACCAT CTTTCAAGββ TCACAAGCTC ACTCTCTGAC 1860
AAGTCAGAAT AGGGACACTG CTTCTATCCC TCCAATGGAG AGATTCTGGC AACCTTTGAA 1920
CAGCCCAGAG CTTGCAACCT AβCCTCACCC AAGAAGACTG GAAAGAGACA TATCTCTCAG 1980
CTTTTTCAGG AGβCGTGCCT GβGAATCCAG βAACTTTTTβ ATGCTAATTA βAAGGCCTGG 2040
ACTAAAAATG TCCACTATGG GGTGCACTCT ACAGTTTTTG AAATGCTAGG AGGCAGAAGG 2100
GGCAGAGAGT AAAAAACATG ACCTGGTAGA AGGAAGAGAG GCAAAGGAAA CTGGGTGGGG 2160
AGGATCAATT AGAGAGGAGG CACCTGGGAT CCACCTTCTT CCTTAGGTCC CCTCCTCCAT 2220
CAGCAAAGGA GCACTTCTCT AATCATGCCC TCCCGAAGAC TββCTGGGAG AAGGTTTAAA 2280
AACAAAAAAT CCAGGAGTAA GAGCCTTAGG TCAGTTTGAA ATTGGAGACA AACTGTCTGG 2340
CAAAGGGTGC GAGAGGGAGC TTGTGCTCAG GAGTCCAGCC GTCCAGCCTC GGGGTGTAGβ 2400
TTTCTGAGGT GTGCCATTGG GGCCTCAGCC TTCTCTGGTG ACAGAGGCTC AGCTGTGGCC 2460
ACCAACACAC AACCACACAC ACACAACCAC ACACACAAAT GGGGGCAACC ACATCCAGTA 2520
CAAGCTTTTA CAAATβTTAT TAGTGTCCTT TTTTATTTCT AATGCCTTGT CCTCTTAAAA 2580
GTTATTTTAT TTβTTATTAT TATTTGTTCT TGACTGTTAA TTGTGAATβG TAATGCAATA 2640
AAGTGCCTTT GTTAGATGGT GAAAAAAAAA AAAAAAAAAA AAAAAAAAAA A
A52 Protein sequence : βene name: Hypothetical protein FLJ20063 Unigene number: Hs.5940 Probeset Accession # : AA053660
Protein Accession # : none found Signal sequence: none found Transmembrane domains : 289-311 EGF domain: 45-74 SEA domain: 80-196
Cellular Localization: plasma membrane
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I i I I I
MVPSETQSNN EMSPTTEDNQ SSGPPTGTAL LETSTLNSTG PSNPCQDDPC ADNSLCVKLH 60 NTSFCLCLEG YYYNSSTCKK GKVFPGKISV TVSETFDPEE KHSMAYQDLH SEITSLFKDV 120 FGTSVYGQTV ILTVSTSLSP RSEMRADDKF VDVTIVTILA ETTSDNEKTV TEKINKAIRS 180 SSSNFLNYDL TLRCDYYGCN QTADDCLNGL ACDCKSDLQR PNPQSPFCVA SSLKCPDACN 240 AQHKQCLIKK SGGAPECACV PGYQEDANGN CQKCAFGYSG LDCKDKFQLI LTIVβTIAβl 300 VILSMIIALI VTARSNNKTK HIEEENLIDE DFQNLKLRST GFTNLGAEGS VFPKVRITAS 360 RDSQMQNPYS RHSSMPRPDY
A53 DNA SEQUENCE Gene name: TMPRSS3 Unigene number: Hs.298241 Probeset Accession # : AI538613 Nucleic Acid Accession AB038157 Coding sequence: 202-1566 (underlined sequences correspond to start and stop codons)
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I I I I I I
ACCβββCACC GGACGGCTCG GGTACTTTCβ TTCTTAATTA GGTCATGCCC GTGTGAGCCA 60
GGAAAGGGCT GTGTTTATGG GAAGCCAGTA ACACTGTGGC CTACTATCTC TTCCGTGβTG 120
CCATCTACAT TTTTGGGACT CGβGAATTAT GAGGTAGAGG TGGAGGCGGA GCCGGATGTC 180
AGAGβTCCTG AAATAGTCAC CATGGGGGAA AATGATCCGC CTGCTGTTGA AGCCCCCTTC 240 TCATTCCGAT CGCTTTTTβG CCTTGATGAT TTGAAAATAA GTCCTGTTGC ACCAGATGCA 300 GATGCTGTTG CTβCACAGAT CCTGTCACTG CTGCCATTGA AGTTTTTTCC AATCATCGTC 360 ATTGGGATCA TTGCATTGAT ATTAGCACTG GCCATTGGTC TGGβCATCCA CTTCGACTGC 420 TCAGGGAAGT ACAGATGTCG CTCATCCTTT AAGTGTATCG AGCTβATAβC TCGATβTGAC 480 GGAGTCTCβG ATTGCAAAGA CGGGGAGGAC GAGTACCGCT GTGTCCGGGT GGGTGGTCAC 540 AATGCCGTGC TCCAGGTGTT CACAGCTGCT TCGTGGAAGA CCATGTGCTC CGATGACTGβ 600 AAGGβTCACT ACGCAAATGT TGCCTβTGCC CAACTGGGTT TCCCAAGCTA TGTGAGTTCA 660 GATAACCTCA GAGTGAGCTC GCTGGAGGGG CAGTTCCGGG AGGAGTTTGT GTCCATCGAT 720 CACCTCTTGC CAGATGACAA GGTGACTGCA TTACACCACT CAGTATATGT GAGGGAGGGA 780 TGTβCCTCTG GCCACGTGGT TACCTTGCAG TGCACAGCCT GTGGTCATAG AAGGGGCTAC 840 AGCTCACGCA TCGTGGGTGG AAACATGTCC TTGCTCTCGC AβTββCCCTβ GCAGGCCAGC 900 CTTCAGTTCC AGGGCTACCA CCTGTGCGGG GGCTCTGTCA TCACβCCCCT GTGGATCATC 960 ACTGCTGCAC ACTGTGTTTA TGACTTGTAC CTCCCCAAGT CATGGACCAT CCAGGTGGGT 1020 CTAGTTTCCC TGTTβGACAA TCCAGCCCCA TCCCACTTGG TGGAGAAGAT TGTCTACCAC 1080 AGCAAGTACA AGCCAAAGAG βCTβGGCAAT GACATCGCCC TTATGAAGCT GGCCGGGCCA 1140 CTCACGTTCA ATGAAATGAT CCAGCCTβTG TGCCTGCCCA ACTCTGAAGA GAACTTCCCC 1200 GATGGAAAAG TGTGCTGGAC GTCAGβATGG GGGGCCACAG AGGATGGAGC AGGTGACGCC 1260 TCCCCTGTCC TGAACCACGC GGCCGTCCCT TTGATTTCCA ACAAGATCTG CAACCACAGG 1320 GACGTGTACG GTGGCATCAT CTCCCCCTCC ATGCTCTGCG CGGGCTACCT GACGGGTGGC 1380 GTGGACAGCT βCCAGGGGGA CAGCGGGGGG CCCCTGGTGT GTCAAGAGAG GAGGCTGTGG 1440 AAGTTAGTGG GAGCGACCAG CTTTGGCATC GGCTGCGCAG AGGTGAACAA GCCTGGGGTG 1500 TACACCCGTG TCACCTCCTT CCTGGACTGG ATCCACGAGC AGATββAGAG AGACCTAAAA 1560 ACCTGAAGAG GAAGGGGACA AGTAGCCACC TGAGTTCCTG AGGTGATGAA GACAGCCCGA 1620 TCCTCCCCTG βACTCCCβTG TAGGAACCTβ CACACGAGCA GACACCCTTG CAGCTCTGAG 1680 TTCCGGCACC AGTAβCAβGC CCGAAAGAGG CACCCTTCCA TCTGATTCCA GCACAACCTT 1740 CAAGCTGCTT TTTGTTTTTT GTTTTTTTGA GGTGGAGTCT CGCTCTGTTG CCCAGGCTGG 1800 AGTGCAGTGG CβAAATCCCT GCTCACTβCA GCCTCCGCTT CCCTGGTTCA AGCGATTCTC 1860 TTGCCTCAGC TTCCCCAGTA βCTGGGACCA CAGGTGCCCβ CCACCACACC CAACTAATTT 1920 TTGTATTTTT AGTAGAGACA GGGTTTCACC ATGTTGGCCA GGCTGCTCTC AAACCCCTGA 1980 CCTCAAATGA TGTGCCTGCT TCAGCCTCCC ACAGTGCTGG GATTACAGGC ATGGGCCACC 2040 ACβCCTAGCC TCACGCTCCT TTCTGATCTT CACTAAGAAC AAAAGAAGCA GCAACTTGCA 2100 AGGGCGGCCT TTCCCACTGG TCCATCTGβT TTTCTCTCCA GββGTCTTβC AAAATTCCTG 2160 ACGAGATAAG CAGTTATGTG ACCTCACGTG CAAAGCCACC AACAGCCACT CAGAAAAGAC 2220 GCACCAGCCC AGAAGTGCAG AACTGCAGTC ACTGCACGTT TTCATCTCTA GGGACCAGAA 2280 CCAAACCCAC CCTTTCTACT TCCAAGACTT ATTTTCACAT GTGGGGAGGT TAATCTAGGA 2340 ATGACTCGTT TAAGGCCTAT TTTCATGATT TCTTTGTAGC ATTTGGTGCT TGACGTATTA 2400 TTGTCCTTTG ATTCCAAATA ATATGTTTCC TTCCCTCAAA AAAAAAAAAA AAAAAAAAAA 2460 AAAAAAAA
A54 Protein sequence: Gene name: TMPRSS3a Unigene number: Hs.298241 Probeset Accession # : AI538613 Protein Accession #: BAB20077 Signal sequence: none found Transmembrane domains : 43-65, 239-261 Tryp_SPc domain: 216-444 Cellular Localization: plasma membrane
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MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP IIVIGIIALI 60 LALAIGLGIH FDCSGKYRCR SSFKCIELIA RCDGVSDCKD GEDEYRCVRV GGQNAVLQVF 120 TAASWKTMCS DDWKGHYANV ACAQLGFPSY VSSDNLRVSS LEGQFREEFV SIDHLLPDDK 180 VTALHHSVYV REGCASGHW TLQCTACGHR RGYSSRIVGG NMSLLSQWPW QASLQFQGYH 240 LCGGSVITPL WIITAAHCVY DLYLPKSWTI QVGLVSLLDN PAPSHLVEKI VYHSKYKPKR 300 LGNDIALMKL AGPLTFNEMI QPVCLPNSEE NFPDGKVCWT SβWGATEDGA GDASPVLNHA 360 AVPLISNKIC NHRDVYGGII SPSMLCAGYL TGGVDSCQGD SGGPLVCQER RLWKLVβATS 420 FGIβCAEVNK PGVYTRVTSF LDWIHEQMER DLKT
A55 DNA SEQUENCE
Gene name: Putative G protein-coupled receptor GPCR150 Unigene number: Hs.97101 Probeset Accession #: AA215333
Nucleic Acid Accession #: NM_014373 Coding sequence: 322-1338 (underlined sequences correspond to start and stop codons)
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I I I I I
GTGGCCTCGA GβTGGTGGCA βGGCCGCCCC CTGCAβTCCG GAGACGAACβ CACGGACCGG 60 GCCTCCGβAβ GCAGGTTCGG CTGGAAGGAA CCGCTCTCGC TTCGTCCTAC ACTTGCGCAA 120 ATGTCTCCGA GCTTACTCAC ATAGCATATT GβTATATCAA AATGAAATGC AAGGAACCAA 180 AAATAACATA ATTGAAGGCA GTAAAAGTGA AATTAAATAG GAAGATCATC AGTCAAGGAA 240 GACCCACTGG AGAGGACAGA AAATGAAGCA GTGTTTTATC ATGTGTATTT CAGCAGGTCT 300 TCTTGAAATT TAACTAAAAA TATGACTGCT CTCTCTTCAG AGAACTGCTC TTTTCAβTAC 360 CAGTTACGTC AAACAAACCA GCCCCTAGAC GTTAACTATC TGCTATTCTT GATCATACTT 420 GGGAAAATAT TATTAAATAT CCTTACACTA GGAATGAGAA GAAAAAACAC CTβTCAAAAT 480 TTTATβGAAT ATTTTTGCAT TTCACTAGCA TTCGTTGATC TTTTACTTTT GGTAAACATT 540 TCCATTATAT TGTATTTCAG GGATTTTGTA CTTTTAAGCA TTAGGTTCAC TAAATACCAC 600 ATCTGCCTAT TTACTCAAAT TATTTCCTTT ACTTATGGCT TTTTGCATTA TCCAGTTTTC 660 CTGACAGCTT GTATAGATTA TTGCCTGAAT TTCTCTAAAA CAACCAAGCT TTCATTTAAG 720 TGTCAAAAAT TATTTTATTT CTTTACAGTA ATTTTAATTT GGATTTCAGT CCTTGCTTAT 780 GTTTTGGGAG ACCCAGCCAT CTACCAAAGC CTβAAββCAC AGAATGCTTA TTCTCGTCAC 840 TCTCCTTTCT ATGTCAGCAT TCAGAβTTAC TGGCTβTCAT TTTTCATββT GATGATTTTA 900 TTTGTAGCTT TCATAACCTG TT6GGAAGAA GTTACTACTT TGβTACAβGC TATCAGGATA 960 ACTTCCTATA TβAATGAAAC TATCTTATAT TTCCTTTTT CATCCCACTC CAGTTATACT 1020 GTGAGATCTA AAAAAATATT CTTATCCAAG CTCATTGTCT GTTTTCTCAβ TACCTGGTTA 1080 CCATTTGTAC TACTTCAGGT AATCATTGTT TTACTTAAAG TTCAβATTCC AβCATATATT 1140 GA6ATGAATA TTCCCTGGTT ATACTTTGTC AATAGTTTTC TCATTGCTAC AGTGTATTGG 1200 TTTAATTGTC ACAAGCTTAA TTTAAAAβAC ATTGGATTAC CTTTGGATCC ATTTGTCAAC 1260 TCGAAGTGCT GCTTCATTCC ACTTACAATT CCTAATCTTG AGCAAATTGA AAAGCCTATA 1320 TCAATAATGA TTTGTTAATA TTATTAATTA AAAGTTACAG CTGTCATAAG ATCATAATTT 1380 TATGAACAGA AAGAACTCAG βACATATTAA AAAATAAACT GAACTAAAAC AACTTTTGCC 1440 CCCTGACTGA TAGCATTTCA GAATGTβTCT TTTGAAGGGC TATACCAGTT ATTAAATAGT 1500 βTTTTATTTT AAAAACAAAA TAATTCCAAG AAGTTTTTAT AGTTATTCAG GGACACTATA 1560 TTACAAATAT TACTTTGTTA TTAACACAAA AAGTGATAAG AGTTAACATT TGGCTATACT 1620 GATGTTTGTG TTACTCAAAA AAACTACTGβ ATGCAAACTG TTATGTAAAT CTβAβATTTC 1680 ACTGACAACT TTAAGATATC AACCTAAACA TTTTTATTAA ATβTTCAAAT βTAAβCAACA 1740 AAAAAAAAA
A56 Protein sequence βene name: Putative G protein-coupled receptor GPCR150 Unigene number: HS.97101 Protein Accession #: NP_055188 Signal sequence: none found Transmembrane domains : 23-45, 59-81, 97-119, 138-160, 184-206, 241-263, 276-297 Cellular Localization: plasma membrane
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I I I
MTALSSENCS FQYQLRQTNQ PLDVNYLLFL IILGKILLNI LTLGMRRKNT CQNFMEYFCI 60 SLAFVDLLLL VNISIILYFR DFVLLSIRFT KYHICLFTQI ISFTYGFLHY PVFLTACIDY 120 CLNFSKTTKL SFKCQKLFYF FTVILIWISV LAYVLβDPAI YQSLKAQNAY SRHCPFYVSI 180 QSYWLSFFMV MILFVAFITC WEEVTTLVQA IRITSYMNET ILYFPFSSHS SYTVRSKKIF 240 LSKLIVCFLS TWLPFVLLQV IIVLLKVQIP AYIEMNIPWL YFVNSFLIAT VYWFNCHKLN 300 LKDIGLPLDP FVNWKCCFIP LTIPNLEQIE KPISIMIC
A57 DNA SEQUENCE
Gene name: ESTs, Weakly similar to CGHU7L collagen alpha l(III) chain precursor [H. sapiens]
Unigene number: Hs.19322
Probeset Accession #: AA088458
Nucleic Acid Accession #: AA088458
Coding sequence: 862-1995 (underlined sequences correspond to start and stop codons)
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I I I I βCCCTTβGAC ACTGACATGG ACTGAAGβAG TAGAATGGAG CACGAββACA CTGACATGGA 60 CTGAAGAAAA AGGAGCTGGA GCAGGAGAAG GAGGTGCTGC TβCAβGGTTT GGAGATGATG 120 GCGCGGGGCC GCGACTGGTA CCAGCAGCAG CTGCAACGAG TGCAGGAGCG CCAGCGCCGC 180 CTGGβCCAGA GCAGAGCCAG CGCCGACTTT GGGGCTGCAG GGAGCCCCCG CCCACTGGGG 240 CGGCTACTGC CCAAGGTACA AGAGGTGβCC CGGTGCCTGG GGGAβCTβCT GGCTGCAGCC 300 TGTGCCAGCC GGβCCCTGCC CCCGTCCTCC TCCGGGCCCC CCTGCCCTGC CCTGACGTCC 360 ACCTCACCCC CββTCTGGCA GCAGCAGACC ATCCTCATGC TGAAGGAGCA GAACCGACTC 420 CTCACCCAGG AGGTGACCGA GAAGAGTGAG CGCATCACGC AGCTGGAGCA GGAGAAGTCG 480 GCGCTCATTA AGCAGCTGTT TGAGGCCCGC GCCCTGAGCC AGCAGGACGG GGGACCTCTG 540 GATTCCACCT TCATCTAGTC CTTGTGGβCC GCGTGGGCCC CCAGGβCCAG CCTGGCACTC 600 AGCCCTTCGA GββTGGGCGC CCCATCGCAC CCACCCTCTC TGGCTβGAGA CCCCCGGCAG 660 GCCCAGGCAC AGTCCCGGAG TGβGCGCCTT CCTGCCGCCC TTGCCAGATG GGCTCCCCAG 720 GCCTGCCCCC GGCTGGTCCC CGCACCGAβC GCTTGACTCC GTTTKGGCTC CTGGTTGYTG 780 ACATGGGCTG GGGGCTCTCT TGAGTCCGCA TAGTCCGCAG CTACTACTGG CCGCTGTCAβ 840 TGGACAGTββ GGTACCCCTC CATGAβTTAβ CGTCCCCCCG TTTCCAGCGG TGCCGCCCTG 900 GGTCCCATCT TCAGGβAAAG GCACTGCCCA CGCCAGGCTβ CACTTCCAAC AACGGGCAGC 960 AGAGGGCGCG GGGCGGCTCC GACGCGGGTC CAAGGGCAGC TTCCCGCTCA ACCAGGGCAC 1020 CAGGACGAββ TGGCTGTAGC TCGGACGGAC GGAAGTAGAT GGAGGGGGTG GGGACGGCCT 1080 GTAAGCGββG GGTGCCTGCC TGβCTβGGGA GCCCCAGGGA TAGCGGTCGG ACTTCAGGTT 1140 CTGGCCAAGG CTGAGGGACC CTβGCTGCAG CGGATCGGCA CGCCGGGTGG GCGAGAGCTT 1200 GβCCTβCATβ TGCCTCCCAC AGACCCTGGG GTGATGGCCT TCCCCCTCTT GGCCGGGACG 1260 TTGCCCCACG TTGAβTCCCA CACAACATCC TGTGAGCCTG GCTCCCCAGG AGGGCCCCCA 1320 GACAGCTCCC AGGCACGTCA TAGGCAAAGC CTGTTTCCCC CGACTCAGGA TTTCCAAGGC 1380 CTGGGGTCCT GCTCACCCCC CTTTGCTCTC ACGCCCAGCC TGTCCCCAGG TTTCAGCTGG 1440 GAGAGGCCAC CTCCCTCAβC CAAGGAAAAC GAβAACCCCC AGGGTACAGG AGβAGGCTGG 1500 GβCAββTCCC CTTGGGTGTC ACTCCCTCAG CCCCTGCCCA GGCCCACTCC CGCTGβTGCT 1560 ββAGTACGCA CTGGTGGGGG GGCCCTGCTC AGCCCAACCT GGAGGGTCCC AGTGTCACCA 1620 GAACCAGGGG CACGGCAACA GCATCGATGG GTTCTGCAGC CCAGGGCCCC CGATGCGGGG 1680 TCAGTGTGTG TGGGGCGCAG GGCCTCCβAT GCGGGGTCAG TGCGTGGGGG GCGCAGGGCC 1740 CCCGATGCGG GβTCAGTGCG TβGGβββCGC AGββCCCCCT CGTGTCCAGG GCACTTTGGT 1800 ACACTGTCCC ACAAGGCACC TGTCTCAGAG GAβGGGCCCT GGCAGGCAGC GTββCAACTC 1860 CCTTCCGGAG CCCAGCTCCA TGCTAACCTG CCCACAGCAA CCCCACAGAG CCACATTCCC 1920 TGCTGCACCT GGTCTGCAGG GGTGTCCCAG GACAGGCCCA AGTCAβCCCA GCATGCACCT 1980 GCCCTCCTAC CCTGAAGATG GβAGTGGGCT TTCCAGGGGA CATAAGGATG TCAGGCCTGG 2040 ACCTCCTGGG CAGGAAAGGG TβCAββTCCT GAGGGCCTGT GCCCCACAGC CCCAGCACCC 2100 AGβTGGACTG CAGCGCAGTG GGTGGβCCAG TGGCAGCCAG GβAGAAGCCC CCCGTCAGCA 2160 GGCTGGGβTC TGCCCACCAG GGCCTCCCCA CGTCTGCCTT TGAGGβTGCC TGCCATGCCC 2220 TGGGGGATCC TGGCATCTTT ACTGGACTGG AAGCAGGAβA CAGAACAGTG TCTGTCCCGG 2280 GGTβACTTCA TCAGGAGACC GCCCACATAG AGCTGGACCC CGCAGCTGAA GCGGAAATGT 2340 GAGACAGGCT GβCACCTCCβ GAAAAACTGC CTTTCAGCCT TGβTGTTCCG TGCAAGGTGA 2400 AAAGAAATAG GTCCTCCCAG TTTACAGCTT GAAATCAGGC TAGTGAGTGG CCCTGGAGAC 2460 CACGAβGGGA GAATTTAAAG GCCCCGGCTG GCAGGGTCTA GGTGGCTGGC AGAGβCACAT 2520 GCAβACCCTG CCTGGAGCCT GCCCTAGGAC GCTGGGCGGG TCAGTCTCCG TGCAGGATGT 2580 GAβCAβCGTC CCTGGGCTCT ATCCGCGAGG TGCCAGTAGC GTGTGCAGGT ACATACACGT 2640 GC6TGCACAC TGTGATβACA CCCββAAATG TCTCAGGATG TTGAAATGTG TCCTTβGGGG 2700 CAGAAβTGTC CCCAβTTGAG AATCTGCCCC AGAGGAACAC ACCCACACCA GGCCTCAGGA 2760 TTTTGTβTTβ ATCAAGTTCC AAGGAAAAGG AACATCTCAG CCGββCGTGG TGGTTCACβC 2820 CTGGAATCCC AGCACTTGAG GCCAGGAGTT CCAGAGCAGC CTβeecAAcβ CAGTGAGAGA 2880 CCCCATCTCT ACAARAAAAA AAAAAGAAAG AAAGAAAATβ AGAGATCCAβ GTTTAAAAAT 2940 TCATAAACAC CACAAGGAAA CAATACACTA TGAGACCCAβ CAGAAGCAAC AGATTGACTC 3000 TAGACCCAGA TACTAGAATT ATCAGAGAGA ATATAAAGTA ACAGTGTTTT ATATATCTAA 3060 AGAAATAAAA GAGATTTCTG GAAACATGAA AAAAAA
A58 DNA sequence
Gene name: ESTs Unigene number: Hs.157601 Probeset Accession #: W07459 Nucleic Acid Accession #: AC005383 Coding Sequence: 328-2751 (underlined sequences correspond to start and stop codons)
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I I I I I I
GACAGTGTTC GCGGCTGCAC CGCTCGGAGG CTβGGTGACC CGCGTAGAAG TGAAGTACTT 60 TTTTATTTGC AGACCTGGGC CGATGCCGCT TTAAAAAACβ CGAGGGGCTC TATGCACCTC 120 CCTGGCGGTA βTTCCTCCGA CCTCAGCCGG GTCβββTCβT 6CCGCCCTCT CCCAGβAGAG 180 ACAAACAGGT GTCCCACGTG GCAGCCGCGC CCCGGGCGCC CCTCCTGTGA TCCC6TAGCG 240 CCCCCTGGCC CGAβCCGCGC CCβGGTCTGT GAGTAβAβCC GCCCGGGCAC CGAGCGCTGG 300 TCGCCGCTCT CCTTCCGTTA TATCAACATG CCCCCTTTCC TGTTGCTGGA GGCCGTCTGT 360 GTTTTCCTGT TTTCCAGAGT GCCCCCATCT CTCCCTCTCC AGGAAGTCCA TGTAAGCAAA 420 GAAACCATCG GGAAGATTTC AGCTGCCAGC AAAATGATGT GGTGCTCGGC TGCAGTGGAC 480 ATCATGTTTC TGTTAGATGG GTCTAACAGC GTCGGGAAAG GGAGCTTTGA AAGGTCCAAG 540 CACTTTGCCA TCACAGTCTG TGACβGTCTG βACATCAGCC CCGAGAβGGT CAGAGTGβGA 600 GCATTCCAGT TCAGTTCCAC TCCTCATCTG βAATTCCCCT TGGATTCATT TTCAACCCAA 660 CAGGAAGTGA AGGCAAGAAT CAAGA6GATG GTTTTCAAAG GAGGGCβCAC GGAGACGβAA 720 CTTGCTCTGA AATACCTTCT GCACAGAGGG TTGCCTGGAG GCAGAAATGC TTCTGTGCCC 780 CAGATCCTCA TCATCGTCAC TGATβGGAAG TCCCAβGGGG ATGTGGCACT GCCATCCAAG 840 CAβCTGAAGG AAAGGGGTGT CACTGTGTTT GCTGTGGGGG TCAGβTTTCC CAGβTGGGAG 900 GAGCTGCATG CACTGGCCAG CGAGCCTAGA GGβCAGCACG TβCTβTTGGC TGAGCAGGTG 960 GAGGATGCCA CCAACGGCCT CTTCAGCACC CTCAGCAGCT CGGCCATCTG CTCCAGCGCC 1020 ACGCCAGACT GCAGGGTCGA GβCTCACCCC TβTGAGCACA GGACGCTGGA GATGGTCCGG 1080 GAGTTCGCTG GCAATGCCCC ATGCTGβAGA GGATCGCGGC GGACCCTTGC GGTGCTGGCT 1140 GCACACTGTC CCTTCTACAG CTGGAAGAGA GTGTTCCTAA CCCACCCTGC CACCTGCTAC 1200 AGGACCACCT βCCCAGGCCC CTβTGACTCG CAGCCCTGCC AGAATGGAGG CACATGTβTT 1260 CCAGAAGGAC TGGACGGCTA CCAβTGCCTC TGCCCGCTGG CCTTTGGAGG GGAGGCTAAC 1320 TGTGCCCTGA AGCTGAGCCT GGAATGCAGG GTCGACCTCC TCTTCCTGCT GGACAGCTCT 1380 GCGGβCACCA CTCTGGACGG CTTCCTGCGG GCCAAAGTCT TCGTGAAGCG GTTTGTGCGG 1440 GCCGTGCTGA βCGAGGACTC TCGGGCCCGA GTGGGTβTGG CCACATACAG CAGGGAGCTG 1500 CTGGTGGCGG TGCCTGTGGG GGAGTACCAG GATGTGCCTβ ACCTGGTCTG GAGCCTCGAT 1560 GGCATTCCCT TCCGTGGTGG CCCCACCCTG ACGGGCAGTG CCTTGCGGCA ββCGGCAGAG 1620 CGTΘ3CTTCG GGAGCGCCAC CAGGACAGGC CAGGACCGGC CACGTAGAGT GGTGGTTTTG 1680 CTCACTGAGT CACACTCCGA GGATGAGGTT GCGGGCCCAG CGCGTCACGC AAGGGCGCGA 1740 GAGCTGCTCC TGCTGGGTGT AGGCAGTGAG GCCGTGCGGG CAGAGCTGGA GGAGATCACA 1800 GGCAGCCCAA AGCATGTGAT GGTCTACTCG GATCCTCAGG ATCTGTTCAA CCAAATCCCT 1860 GAGCTGCAGG GGAAGCTGTG CAGCCGGCAG CGGCCAGGGT GCCGGACACA AGCCCTGGAC 1920 CTCGTCTTCA TGTTGGACAC CTCTGCCTCA GTAGGGCCCG AGAATTTTGC TCAGATGCAG 1980 AGCTTTGTGA GAAβCTGTGC CCTCCAβTTT GAGGTGAACC CTGACGTGAC ACAGGTCGGC 2040 CTGGT6GTGT ATGGCAGCCA GGTGCAGACT GCCTTCGGCC TGGACACCAA ACCCACCCGG 2100 GCTGCGATβC TGCβGGCCAT TAGCCAGGCC CCCTACCTAG GTGβGGTGGG CTCAGCCGGC 2160 ACCGCCCTGC TGCACATCTA TGACAAAβTG ATGACCGTCC AβAGGGGTGC CCGGCCTGGT 2220 GTCCCCAAAβ CTGTGGTGGT GCTCACAGGC GGGAGAGGCG CAβAGGATGC AGCCGTTCCT 2280 GCCCAGAAGC TGAGGAACAA TβGCATCTCT GTCTTGGTCG TGβGCGTGGG GCCTGTCCTA 2340 AGTGAGGGTC TGCGGAGGCT TβCAGGTCCC Cβ∞ATTCCC TβATCCACβT GGCAGCTTAC 2400 GCCGACCTGC GGTACCACCA GGACGTGCTC ATTβAGTGGC TGTGTGGAGA AGCCAAGCAG 2460 CCAGTCAACC TCTGCAAACC CAGCCCGTβC ATGAATβAβG GCAGCTGCGT CCTGCAGAAT 2520 GGGAGCTACC GCTGCAAGTG TCGGGATGGC TGGβAGGGCC CCCACTGCGA GAACCGTGAG 2580 TGGAGCTCTT GCTCTGTATG TGTGAGCCAG GGATGGATTC TTGAGACGCC CCTGAGGCAC 2640 ATGGCTCCCβ TGCAGGAGGG CAGCAGCCβT ACCCCTCCCA βCAACTACAG AGAAGβCCTβ 2700 GGCACTGAAA TGGTGCCTAC CTTCTGβAAT GTCTGTGCCC CAββTCCTTA GAATGTCTGC 2760 TTCCCGCCGT βGCCAGGACC ACTATTCTCA CTGAGββAβG AGGATGTCCC AACTGCAGCC 2820 ATGCTGCTTA βAGACAAGAA AGCAGCTGAT GTCACCCACA AACGATGTTG TTGAAAAβTT 2880 TTGATGTGTA AGTAAATACC CACTTTCTGT ACCTGCTGTG CCTTGTTGAG GCTATGTCAT 2940 CTGCCACCTT TCCCTTGAGG ATAAACAAGG GGTCCTGAAG ACTTAAATTT AGCGGCCTGA 3000 CGTTCCTTTG CACACAATCA ATGCTCGCCA GAATGTTGTT GACACAGTAA TGCCCAGCAG 3060 AGGCCTTTAC TAGAGCATCC TTTGGACGGC GAAGGCCACG GCCTTTCAAG ATGGAAAGCA 3120 GCAβCTTTTC CACTTCCCCA GAGACATTCT GGATGCATTT GCATTGAGTC TGAAAGGβGG 3180 CTTGAGGGAC GTTTβTβACT TCTTGGCGAC TGCCTTTTGT GTGTGGAAGA GACTTGGAAA 3240 GGTCTCAGAC TGAATβTβAC CAATTAACCA GCTTGGTTGA TGATGGGGGA GGGβCTGAGT 3300 TGTGCATGβG CCCAGGTCTG GAGGβCCACG TAAAATCGTT CTGAGTCGTG AGCAGTGTCC 3360 ACCTTβAAGG TCTTC A59 Protein sequence
Gene name: ESTs
Unigene number: Hs.157601
Protein Accession # : none found
Signal sequence: 1-17
Transmembrane domains : none found
VGW domains: 49-223; 341-518; 529-706
EβF domains: 298-333; 715-748
Cellular Localization: secreted
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I I I I I I
MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN 60
SVGKβSFERS KHFAITVCDβ LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR 120
MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180
FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240
PCEHRTLEMV REFAβNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300
SQPCQNGβTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL 360
RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT 420
LTGSALRQAA ERGFGSATRT GQDRPRRVW LLTESHSEDE VAGPARHARA RELLLLGVGS 480
EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540
SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600
APYLGGVGSA GTALLHIYDK VMTVQRGARP βVPKAWVLT GGRβAEDAAV PAQKLRNNβl 660
SVLWGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK QPVNLCKPSP 720
CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR EWSSCSVCVS QGWILETPLR HMAPVQEGSS 780 RTPPSNYREG LβTEMVPTFW NVCAPβP
A60 DNA SEQUENCE
Gene name: Homo sapiens type II membrane serine protease mRNA
Unigene number: Hs.63325 Probeset Accession #: AA411502 Nucleic Acid Accession #: NM_016425 Coding sequence: 1-1314 (underlined sequences correspond to start and stop codons)
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I I I I I I
ATGTTACAGG ATCCTβACAG TGATCAACCT CTGAACAGCC TCGATGTCAA ACCCCTGCGC 60
AAACCCCβTA TCCCCATβGA GACCTTCAGA AAGGTβGGGA TCCCCATCAT CATAGCACTA 120
CTGAGCCTGβ CGAGTATCAT CATTGTGGTT GTCCTCATCA AGGTβATTCT GGATAAATAC 180
TACTTCCTCT GCGGGCAGCC TCTCCACTTC ATCCCGAββA AβCAGCTGTG TGACGGAGAG 240
CTGGACTGTC CCTTGGGGβA GGACGAGGAG CACTGTβTCA AβAβCTTCCC CGAAGGGCCT 300
GCAGTGGCAG TCCGCCTCTC CAAGβACCGA TCCACACTGC AGGTβCTGGA CTCGGCCACA 360
G6GAACTGGT TCTCTGCCTG TTTCβACAAC TTCACAGAAG CTCTCGCT6A GACAGCCTGT 420
AGGCAGATGG GCTACAGCAG CAAACCCACT TTCAGAβCTG TGGAβATTGβ CCCAGACCAG 480
GATCTGGATG TTGTTGAAAT CACAGAAAAC AGCCAGGAGC TTCGCATβCβ GAACTCAAGT 540
GGGCCCTGTC TCTCAGGCTC CCTGβTCTCC CTGCACTGTC TTGCCTGTGG GAAGAGCCTG 600
AAGACCCCCC GTβTββTGGG TGGGGAGβAβ GCCTCTGTGG ATTCTTGGCC TTGGCAGGTC 660
AGCATCCAGT ACGACAAACA GCACGTCTGT ββAβGGAGCA TCCTGGACCC CCACTGGGTC 720
CTCACGGCAG CCCACTGCTT CAGGAAACAT ACCGATGTGT TCAACTGGAA GGTGCGGGCA 780
GGCTCAGACA AACTG6GCAG CTTCCCATCC CTGGCTGTGG CCAAGATCAT CATCATTGAA 840
TTCAACCCCA TGTACCCCAA AGACAATGAC ATCβCCCTCA TGAAGCTGCA GTTCCCACTC 900
ACTTTCTCAG GCACAGTCAG GCCCATCTGT CTGCCCTTCT TTGATGAGGA GCTCACTCCA 960
GCCACCCCAC TCTGGATCAT TGGATGGGGC TTTACGAAGC AGAATGGAGG GAAGATGTCT 1020
GACATACTGC TGCAGGCGTC AGTCCAββTC ATTGACAGCA CACGGTGCAA TGCAGACGAT 1080
GCβTACCAGG GGGAAGTCAC CGAGAAGATβ ATGTGTGCAG GCATCCCGGA AGGGGGTGTG 1140
GACACCTGCC AβGGTGACAG TGGTGGGCCC CTGATGTACC AATCTGACCA GTGGCATGTG 1200
GTGGGCATCG TTAGCTGGGG CTATGGCTGC GGGGGCCCGA GCACCCCAGG AGTATACACC 1260 AAGGTCTCAG CCTATCTCAA CTGβATCTAC AATGTCTGβA AGGCTGAGCT GTAA
A61 Protein sequence :
Gene name: Homo sapiens type II membrane serine protease mRNA
Unigene number: Hs.63325
Probeset Accession #: AA411502
Protein Accession #: NP_057509
Signal sequence: none found
Transmembrane domains: 31-53
LDLa domain: 54-94
Tryp_SPc domain: 204-429
Cellular Localization: plasma membrane/ER
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MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIW VLIKVILDKY 60
YFLCβQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEβP AVAVRLSKDR STLQVLDSAT 120
GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDWEITEN SQELRMRNSS 180
GPCLSGSLVS LHCLACGKSL KTPRWGGEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV 240
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL 300
TFSGTVRPIC LPFFDEELTP ATPLWIIβWG FTKQNGGKMS DILLQASVQV IDSTRCNADD 360
AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT 420 KVSAYLNWIY NVWKAEL A62 DNA SEQUENCE Gene name : ESTs; Weakly similar to LITHOSTATHINE 1 BETA PRECURSOR [H. sapiens] Unigene number: Hs.105484 Probeset Accession #: AA314779 Nucleic Acid Accession # : none found Coding sequence: 103-579 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 1 1 1 1 I 1 | 1 J 1 1 1 CCAAACAGAT TTGCAGATCA AGGAGAACCC AGGAGTTTCA AAGAAGCGCT AGTAAββTCT 60
CTGAGATCCT TGCACTAGCT ACATCCTCAG GGTAGβAββA AGATGGCTTC CAGAAGCATG 120
CGGCTGCTCC TATTGCTGAG CTGCCTGGCC AAAACAGβAβ TCCTGGGTGA TATCATCATβ 180
AβACCCAβCT GTGCTCCTGβ ATGβTTTTAC CACAAβTCCA ATTβCTATGG TTACTTCAGG 240
AAGCTGAGβA ACTGGTCTGA TGCCGAGCTC GAGTGTCAGT CTTACGGAAA CβGAGCCCAC 300
CTGGCATCTA TCCTGAGTTT AAAGβAAGCC AGCACCATAG CAβAβTACAT AAGTGGCTAT 360
CAGAβAAGCC AGCCGATATG GATTGGCCTG CACGACCCAC AβAAGAGGCA βCAβTββCAG 420
TGGATTGATG GGGCCATGTA TCTGTACAGA TCCTGGTCTG GCAAGTCCAT GGGTGGGAAC 480
AAGCACTGTG CTGAGATGAG CTCCAATAAC AACTTTTTAA CTTGβAGCAG CAACGAATβC 540
AACAAGCGCC AACACTTCCT βTGCAAGTAC CGACCATAGA βCAAβAATCA ACATTCTβCT 600
AACTCCTGCA CCAGCCCCGT CCTCTTCCTT TCTGCTAGCC TCβCTAAATC TGCTCATTAT 660
TTCAGAGGGG AAACCTAGCA AACTAAGAβT GATAAGGGCC CTACTACACT GGCTTTTTTA 720
GGCTTAGAGA CAGAAACTTT AGCATTGGGC CCAGTAGT6G CTTCTAGCTC TAAATGTTTG 780
CCCCGCCATC CCTTTCCACA GTATCCTTCT TCCCTCCTCC CCTGTCTCTβ GCTβTCTCGA 840
GCAGTCTAGA AGAGTGCATC TCCAGCCTAT GAAACAβCTβ GGTCTTTGβC CATAAGAAβT 900
AAAGATTTGA AGACAGAAGG AAβAAACTCA GGAGTAAGCT TCTAGACCCC TTCACCTTCT 960
ACACCCTTCT GCCCTCTCTC CATTGCCTGC ACCCCACCCC AGCCACTCAA CTCCTGCTTG 1020
TTTTTCCTTT GGCCATAGβA AGβTTTACCA GTAGAATCCT TGCTAβGTTG ATGTGGGCCA 1080
TACATTCCTT TAATAAACCA TTGTGTACAT AAGAGAAAAA AAAAAAAAAA AAAAAAAAAA
A63 Protein sequence: Gene name: ESTs; Weakly similar to LITHOSTATHINE 1 BETA PRECURSOR [H.sapiens] Unigene number: Hs.105484 Probeset Accession #: AA314779 Protein Accession #: none found Signal sequence: 1-22 Transmembrane domains : none found C-type lectin domain: 47-156 Cellular Localization: secreted
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M IASRSMRLLL LILSCLAKTGV LIGDIIMRPSC AIPGWFYHKSN CIYGYFRKLRN WISDAELECQS 60 YGNGAHLASI LSLKEASTIA EYISβYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG 120 KSMβGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
A64 DNA SEQUENCE Gene name: Cadherin 3, P-cadherin (placental) Unigene number: Hs .2877 Probeset Accession #: X63629 Nucleic Acid Accession # : X63629 Coding sequence: 54-2543 (start and stop codons are underlined)
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1 1 1 1 | 1 | 1 | 1 | 1 GCGGAACACC GGCCCGCCGT CGCGGCAGCT GCTTCACCCC TCTCTCTGCA GCCATGGGGC 60
TCCCTCGTGG ACCTCTCGCG TCTCTCCTCC TTCTCCAGGT TTGCTGGCTβ CAGTGCGCGG 120
CCTCCGAGCC GTGCCGGGCG GTCTTCAGββ AGGCTGAAGT GACCTTGβAG GCGGGAGβCβ 180
CGGAβCAββA GCCCGGCCAG GCGCTGGGGA AAGTATTCAT GGGCTGCCCT GGGCAAGAGC 240
CAGCTCTGTT TAGCACTGAT AATGATGACT TCACTGTGCβ GAATGGCGAG ACAGTCCAGG 300
AAAGAAβGTC ACTGAAGGAA AββAATCCAT TGAAGATCTT CCCATCCAAA CGTATCTTAC 360
GAAGACACAA GAGAGATTGG GTGGTTβCTC CAATATCTβT CCCTGAAAAT GGCAAβββTC 420
CCTTCCCCCA GAGACTGAAT CAGCTCAAGT CTAATAAAβA TAGAGACACC AAGATTTTCT 480
ACAGCATCAC GGGGCCGGGG GCAβACAβCC CCCCTGAGGG TβTCTTCβCT GTAGAGAAGβ 540
AGACAGGCTG GTTGTTGTTG AATAAGCCAC TGGACCGGGA GβAGATTGCC AAGTATGAGC 600
TCTTTGβCCA CGCTGTGTCA GAGAATββTβ CCTCAGTGGA GGACCCCATG AACATCTCCA 660
TCATCGTGAC CGACCAGAAT βACCACAAGC CCAAGTTTAC CCAGGACACC TTCCβAGGGA 720
GTβTCTTAGA GGGAGTCCTA CCAGGTACTT CTGTGATGCA GGTGACAGCC ACAGATGAGG 780
ATGATGCCAT CTACACCTAC AATGGGGTβG TTGCTTACTC CATCCATAβC CAAGAACCAA 840
AGGACCCACA CGACCTCATG TTCACAATTC ACCGGAGCAC AGGCACCATC AGCGTCATCT 900
CCAGTGGCCT GGACCGGGAA AAAGTCCCTG AGTACACACT GACCATCCAG GCCACAGACA 960
TGGATGGGGA CGGCTCCACC ACCACGGCAG TGGCAGTAGT GGAGATCCTT GATGCCAATG 1020
ACAATβCTCC CATGTTTβAC CCCCAGAAGT ACGAGGCCCA TGTGCCTGAG AATβCAβTGG 1080
GCCATGAGβT GCAGAGGCTG ACGGTCACTG ATCTGGACβC CCCCAACTCA CCAGCβTGGC 1140
GTGCCACCTA CCTTATCATG GGCGGTGACG ACGGGGACCA TTTTACCATC ACCACCCACC 1200
CTGAβAβCAA CCAGGGCATC CTGACAACCA GβAAGGGTTT GGATTTTGAG GCCAAAAACC 1260
AGCACACCCT GTACβTTGAA βTGACCAACG AGGCCCCTTT TGTGCTGAAG CTCCCAACCT 1320
CCACAGCCAC CATAGTGGTC CACGTGGA6G ATGTGAATGA GGCACCTGTG TTTGTCCCAC 1380
CCTCCAAAGT CGTTGAGGTC CAGGAGββCA TCCCCACTGG GGAGCCTGTG TGTβTCTACA 1440
CTGCAGAAGA CCCTGACAAG βAβAATCAAA AGATCAGCTA CCGCATCCTG AGAGACCCAG 1500 CAGGGTGGCT AGCCATGGAC CCAGACAGTG βGCAGGTCAC AGCTGTGGGC ACCCTCGACC 1560 GTGAGGATGA GCAGTTTGTG AGGAACAACA TCTATGAAβT CATGβTCTTβ GCCATGGACA 1620 ATGGAAGCCC TCCCACCACT GGCACGβGAA CCCTTCTβCT AACACTGATT GATGTCAACG 1680 ACCATββCCC AβTCCCTGAG CCCCGTCAGA TCACCATCTG CAACCAAAGC CCTGTβCβCC 1740 ACGTGCTGAA CATCACGGAC AAGβACCTGT CTCCCCACAC CTCCCCTTTC CAββCCCAβC 1800 TCACAGATGA CTCAGACATC TACTGGACGG CAβAGGTCAA CGAGβAAGGT βACACAGTGG 1860 TCTTGTCCCT GAAGAAGTTC CTGAAGCAGG ATACATATGA CGT6CACCTT TCTCTGTCTG 1920 ACCATGGCAA CAAAGAGCAG CTGACGGTGA TCAGGGCCAC TGTGTGCGAC TGCCATββCC 1980 ATGTCβAAAC CTGCCCTGGA CCCTGGAAAG GAGGTTTCAT CCTCCCTGTG CTββββGCTG 2040 TCCTGβCTCT GCTβTTCCTC CTGCTGGTGC TGCTTTTGTT GGTGAGAAAG AAβCββAAGA 2100 TCAAGGAGCC CCTCCTACTC CCAGAAGATG ACACCCGTGA CAACGTCTTC TACTATGGCG 2160 AAGAGGGGGG TββCβAAGAG GACCAGβACT ATGACATCAC CCAGCTCCAC CGAGGTCTGG 2220 AGGCCAGGCC GβAGGTβGTT CTCCCCAATβ ACβTGGCACC AACCATCATC CCGACACCCA 2280 TGTACCGTCC TAββCCAβCC AACCCAβATβ AAATCGβCAA CTTTATAATT GAGAACCTGA 2340 AGβCGGCTAA CACAGACCCC ACAGCCCCGC CCTACβACAC CCTCTTGGTG TTCGACTATβ 2400 AGGGCAGCGG CTCCGACGCC GCGTCCCTGA βCTCCCTCAC CTCCTCCGCC TCCβACCAAG 2460 ACCAAGATTA CGATTATCTG AACGAGTGGG βCACCCβCTT CAAGAAβCTG GCAβACATGT 2520 ACGGTββCGG GGAGGACGAC TAGGCGGCCT βCCTGCAGGG CTGββGACCA AACGTCAGGC 2580 CACAGAβCAT CTCCAAGGβG TCTCA6TTCC CCCTTCAGCT GAββACTTCβ GAGCTTβTCA 2640 ββAAGTGGCC GTAGCAACTT GGCGGAGACA βGCTATGAβT CTβACGTTAG AGTGGTTGCT 2700 TCCTTAGCCT TTCAGβATβG AβGAATGTGG GCAGTTTGAC TTCAGCACTβ AAAACCTCTC 2760 CACCTβGGCC AGGGTTGCCT CAGAGGCCAA GTTTCCAGAA GCCTCTTACC TGCCβTAAAA 2820 TGCTCAACCC TGTGTCCTGG GCCTβββCCT GCTGTGACTG ACCTACAGTG GACTTTCTCT 2880 CTGGAATGGA ACCTTCTTAG GCCTCCTGGT GCAACTTAAT AATGCTATCT 2940 TCAAAACGTT AGAGAAAGTT CTTCAAAAGT GCAGCCCAGA GCTGCTGGGC CCACTGGCCG 3000 TCCTGCATTT CTGβTTTCCA GACCCCAATG CCTCCCATTC GGATGGATCT CTGCGTTTTT 3060 ATACTGAGTG TGCCTAGGTT βCCCCTTATT TTTTATTTTC CCTGTTGCβT TGCTATAGAT 3120 GAAβGGTGAG GACAATCβTG TATATβTACT AGAACTTTTT TATTAAAGAA A
A65 Protein sequence : Gene name: Cadherin 3, P-cadherin (placental) Unigene number: Hs.2877 Probeset Accession #: X63629 Protein Accession # : CAA45177 Signal sequence : 1-24 Transmembrane domain: 659-675 (second underlined sequence)
Cellular localization: plasma membrane
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MGLPRGPLAS LLLLQVCWLQ CAASEPCRAV FREAEVTLEA GGAEQEPGQA LGKVFMGCPG 60 QEPALFSTDN DDFTVRNGET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENG 120 KβPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK 180 YELFβHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RGSVLEGVLP GTSVMQVTAT 240 DEDDAIYTYN GWAYSIHSQ EPKDPHDLMF TIHRSTβTIS VISSGLDREK VPEYTLTIQA 300 TDMDGDGSTT TAVAWEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP 360 AWRATYLIMβ GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL 420 PTSTATIWH VEDVNEAPVF VPPSKWEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR 480 DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTG TGTLLLTLID 540 VNDHGPVPEP RQITICNQSP VRHVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD 600 TWLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL 660 GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YGEEGGGEED QDYDITQLHR 720 GLEARPEWL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF 780 DYEGSGSDAA SLSSLTSSAS DQDQDYDYLN EWGSRFKKLA DMYGGGEDD
A66 DNA SEQUENCE
Gene name: ATPase, Ca++ transporting, type 2C, member 1
Unigene number: Hs.106778
Probeset Accession #: N51919
Nucleic Acid Accession #: AF189723
Coding sequence: 1-2712 (underlined sequences correspond to start and stop codons)
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ATGATTCCTG TATTGACATC AAAAAAAGCA AGTGAATTAC CAGTCAGTGA AGTTGCAAGC 60 ATTCTCCAAG CTβATCTTCA GAATGGTCTA AACAAATβTβ AAGTTAGTCA TAGGCGAGCC 120 TTTCATGGCT GGAATGAβTT TGATATTAGT GAAGATGAGC CACTGTGGAA GAAGTATATT 180 TCTCAGTTTA AAAATCCCCT TATTATGCTG CTTCTGGCTT CTCCAβTCAT CAGTGTTTTA 240 ATGCATCAGT TTGATGATGC CGTCAGTATC ACTGTGGCAA TACTTATCβT TGTTACAGTT 300 GCCTTTGTTC AGGAATATCG TTCAGAAAAA TCTCTTGAAG AATTGAGTAA ACTTGTGCCA 360 CCAGAATGCC ATTGTGTβCG TGAAGGAAAA TTGGAGCATA CACTTGCCCG AGACTTGGTT 420 CCAGβTGATA CAGTTTGCCT TTCTGTTGββ GATAGAGTTC CTGCTβACTT ACGCTTGTTT 480 6AGGCTGTGG ATCTTTCCAT TβATβAβTCC ACCTTGACAG GTGAGACAAC GCCTT6TTCT 540 AAGGTGACAG CTCCTCAGCC AβCTβCAACT AATGGAGATC TTGCATCGAG AAβTAACATT 600 GCCTTTATGG GAACACTGGT CAGATGTGGC AAAGCAAAGG GTGTTGTCAT TGGAACAGGA 660 GAAAATTCTG AATTTGβGGA GGTTTTTAAA ATGATGCAAG CAGAAGAGGC ACCAAAAACC 720 CCTCTGCAGA AGAGCATGGA CCTCTTAGGA AAACAACTTT CCTTTTACTC CTTTGGTATA 780 ATAGGAATCA TCATGTTGGT TGGCTGβTTA CTβGGAAAAG ATATCCTββA AATGTTTACT 840 ATTAGTGTAA GTTTGGCTGT AGCAGCAATT CCTGAAGβTC TCCCCATTGT GGTCACAGTG 900 ACGCTAGCTC TTGGTGTTAT GAGAATGGTG AAGAAAAGGG CCATTGTGAA AAAGCTGCCT 960 ATTGTTGAAA CTCTGGGCTG CTGTAATGTβ ATTTGTTCAG ATAAAACTGG AACACTGACG 1020 AAGAATGAAA TGACT6TTAC TCACATATTT ACTTCAGATG GTCTGCATGC TGAGβTTACT 1080 GGAGTTGGCT ATAATCAATT TGGβGAAGTG ATTGTTGATG GTβATGTTGT TCATCGATTC 1140 TATAACCCAG CTGTTAβCAG AATTGTTGAG GCGGGCTGTG TGTGCAATGA TGCTβTAATT 1200 AGAAACAATA CTCTAATGββ GAAGCCAACA GAAGGβeCCT TAATTGCTCT TGCAATGAAG 1260 ATGGGTCTTG ATGGACTTCA ACAAGACTAC ATCAGAAAAG CTGAATACCC TTTTAβCTCT 1320 GAGCAAAAGT GGATGβCTβT TAAGTGTGTA CACCGAACAC AGCAGGACAG ACCACAβATT 1380 TGTTTTATGA AAGGTGCTTA CGAACAAGTA ATTAAβTACT GTACTACATA CCAβAGCAAA 1440 GGGCAGACCT TGACACTTAC TCAβCAGCAG AGAGATGTGT ACCAACAACA GAAGβCACGC 1500 ATGGGCTCAβ CGGGACTCAβ AβTTCTTβCT TTGGCTTCTG βTCCTβAACT GGβACAGCTG 1560 ACATTTCTTβ GCTTGβTβββ AATCATTβAT CCACCTAGAA CTGGTGTβAA AGAAGCTGTT 1620 ACAACACTCA TTGCCTCAGG AβTATCAATA AAAATGATTA CTG6AGATTC ACAGGAGACT 1680 GCAGTTβCAA TCGCCAGTCG TCTGGGATTG TATTCCAAAA CTTCCCAGTC AGTCTCAGGA 1740 GAAGAAATAG ATGCAATGGA TGTTCAGCAG CTTTCACAAA TAGTACCAAA GGTTβCAGTA 1800 TTTTACAβAβ CTAGCCCAAG GCACAAGATG AAAATTATTA AβTCβCTACA GAAGAACGGT 1860 TCAGTTGTAG CCATGACAββ AβATββAβTA AATGATGCAG TTGCTCTGAA GGCTGCAGAC 1920 ATTGβAGTTG CGATGββCCA GACTGGTACA GATGTTTGCA AAGAGGCAGC AGACATGATC 1980 CTAGTββATG ATGATTTTCA AACCATAATG TCTGCAATCG AAGAGGGTAA AGGGATTTAT 2040 AATAACATTA AAAATTTCGT TAβATTCCAβ CTGAGCAC6A GTATAGCAGC ATTAACTTTA 2100 ATCTCATTGβ CTACATTAAT GAACTTTCCT AATCCTCTCA ATGCCATGCA GATTTTGTGG 2160 ATCAATATTA TTATGβATGG ACCCCCAGCT CAGAGCCTTG GAβTAβAACC AGTGGATAAA 2220 βATβTCATTC GTAAACCTCC TCGCAACTGG AAAGACAGCA TTTTGACTAA AAACTTGATA 2280 CTTAAAATAC TTGTTTCATC AATAATCATT GTTTGTGGGA CTTTGTTTGT CTTCTGGCGT 2340 GAGCTACGAG ACAATβTGAT TACACCTCGA GACACAACAA TGACCTTCAC ATGCTTTGTG 2400 TTTTTTGACA TGTTCAATGC ACTAAGTTCC AGATCCCAβA CCAAGTCTGT GTTTGAGATT 2460 GGACTCTGCA GTAATAGAAT GTTTTGCTAT GCAGTTCTTG GATCCATCAT GGβACAATTA 2520 CTAGTTATTT ACTTTCCTCC GCTTCAβAAβ GTTTTTCA6A CTGAGAGCCT AAGCATACTG 2580 GATCTGTTGT TTCTTTTGGG TCTCACCTCA TCAβTβTGCA TAGTββCAβA AATTATAAAG 2640 AAGGTTGAAA GGAGCAGGGA AAAGATCCAG AAGCATβTTA βTTCβACATC ATCATCTTTT 2700 CTTGAAGTAT GA
A67 Protein sequence: Gene name: ATPase, Ca++ transporting, type 2C, member 1 Unigene number: Hs.106778 Probeset Accession #: N51919 Protein Accession #: AAF27813 Signal sequence: none found Transmembrane domains: 60-82, 86-108, 252-274, 282-304, 757-779, 827-849, 856-878 Pfam domains : Cation ATPase N [6-83] , E1-E2 ATPase [89-324] , Hydrolase [328-649] , Cation ATPase C [744-889] Cellular Localization: not determined
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MIPVLTSKKA SELPVSEVAS ILQADLQNGL NKCEVSHRRA FHβWNEFDIS EDEPLWKKYI 60 SQFKNPLIML LLASAVISVL MHQFDDAVSI TVAILIWTV AFVQEYRSEK SLEELSKLVP 120 PECHCVREGK LEHTLARDLV PGDTVCLSVβ DRVPADLRLF EAVDLSIDES SLTGETTPCS 180 KVTAPQPAAT NGDLASRSNI AFMGTLVRCG KAKGWIGTG ENSEFGEVFK MMQAEEAPKT 240 PLQKSMDLLG KQLSFYSFGI IGIIMLVGWL LGKDILEMFT ISVSLAVAAI PEβLPIWTV 300 TLALGVMRMV KKRAIVKKLP IVETLGCCNV ICSDKTGTLT KNEMTVTHIF TSDGLHAEVT 360 GVGYNQFGEV IVDGDWHGF YNPAVSRIVE AGCVCNDAVI RNNTLMGKPT EGALIALAMK 420 MGLDGLQQDY IRKAEYPFSS EQKWMAVKCV HRTQQDRPEI CFMKGAYEQV IKYCTTYQSK 480 GQTLTLTQQQ RDVYQQEKAR MGSAβLRVLA LASGPELGQL TFLGLVGIID PPRTGVKEAV 540 TTLIASGVSI KMITGDSQET AVAIASRLGL YSKTSQSVSG EEIDAMDVQQ LSQIVPKVAV 600 FYRASPRHKM KIIKSLQKNG SWAMTGDGV NDAVALKAAD IGVAMGQTGT DVCKEAADMI 660 LVDDDFQTIM SAIEEGKGIY NNIKNFVRFQ LSTSIAALTL ISLATLMNFP NPLNAMQILW 720 INIIMDGPPA QSLGVEPVDK DVIRKPPRNW KDSILTKNLI LKILVSSIII VCGTLFVFWR 780 ELRDNVITPR DTTMTFTCFV FFDMFNALSS RSQTKSVFEI GLCSNRMFCY AVLGSIMGQL 840 LVIYFPPLQK VFQTESLSIL DLLFLLGLTS SVCIVAEIIK KVERSREKIQ KHVSSTSSSF 900 LEV
A68 DNA SEQUENCE Gene name: bone morphogenetic protein 7 (osteogenic protein 1) (BMP7) Unigene number: Hs.170195 Probeset Accession #: BE616633 Nucleic Acid Accession #: NM_001719 Coding sequence: 123-1418 (underlined sequences correspond to start and stop codons)
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GGGCGCAGCG GGGCCCGTCT GCAGCAAGTG ACCGACGGCC GGGACGGCCG CCTGCCCCCT 60 CTGCCACCTβ GGGCββTβCG GGCCCGGAGC CCGGAGCCCG GGTAGCGCGT AGAGCCGGCG 120 CGATGCACGT GCβCTCACTG CGAGCTGCGG CGCCGCACAG CTTCGTGGCG CTCTGGGCAC 180 CCCTGTTCCT GCTGCGCTCC GCCCTGGCCG ACTTCAGCCT GGACAACGAG GTGCACTCGA 240 GCTTCATCCA CCββCCCCTC CGCAGCCAGG AGCββCGGGA GATβCAGCGC GAGATCCTCT 300 CCATTTTGGG CTTGCCCCAC CGCCCβCβCC CGCACCTCCA GGβCAACCAC AACTCGGCAC 360 CCATGTTCAT GCTGGACCTG TACAACGCCA TGGCGGTGGA GGAGGGCβGC GββCCCβGCG 420 GCCAGGβCTT CTCCTACCCC TACAAGGCCG TCTTCAGTAC CCAGGGCCCC CCTCTGGCCA 480 GCCTβCAAβA TAGCCATTTC CTCACCGACG CCGACATβGT CATGAGCTTC GTCAACCTCG 540 TGGAACATGA CAAGβAATTC TTCCACCCAC GCTACCACCA TCGAGAGTTC CGGTTTGATC 600 TTTCCAAGAT CCCAGAAGGG GAAGCTGTCA CGGCAGCCGA ATTCCββATC TACAAGβACT 660 ACATCCGGGA ACGCTTCGAC AATGAGACGT TCCGGATCAG CGTTTATCAG βTGCTCCAGG 720 AGCACTTGGG CAGGGAATCG GATCTCTTCC TβCTCGACAG CCGTACCCTC TGGGCCTCGG 780 AGGAGGGCTG GCTGGTGTTT GACATCACAβ CCACCAβCAA CCACTGGGTβ GTCAATCCGC 840 GGCACAACCT GGGCCTGCAG CTCTCGGTGG AGACGCTββA TGGβCAβAβC ATCAACCCCA 900 AGTTGβCGGG CCTGATTGGG CGGCACGGGC CCCACAACAA GCAGCCCTTC ATGGTGGCTT 960 TCTTCAAGGC CACGGAGGTC CACTTCCGCA βCATCCβGTC CACGGGGAGC AAACAGCGCA 1020 GCCAGAACCG CTCCAAGACG CCCAAGAACC AGGAAGCCCT GCGGATGGCC AACGTGGCAβ 1080 AGAACAGCAG CAGCGACCAG AββCAGGCCT GTAAGAAGCA CGAGCTGTAT GTCAGCTTCC 1140 GAGACCTβGG CTGGCAGGAC TGGATCATCG CGCCTGAAGG CTACGCCGCC TACTACTGTG 1200 AGGGGGAβTβ TGCCTTCCCT CTGAACTCCT ACATGAACGC CACCAACCAC GCCATCGTGC 1260 AGACGCTGGT CCACTTCATC AACCCGGAAA CGGTGCCCAA GCCCTGCTGT GCGCCCACGC 1320 AGCTCAATGC CATCTCCGTC CTCTACTTCG ATGACAGCTC CAACGTCATC CTGAAGAAAT 1380 ACAGAAACAT GGTGGTCCGG GCCTGTGGCT βCCACTAβCT CCTCCβAGAA TTCAGACCCT 1440 TTGGGGCCAA GTTTTTCTGG ATCCTCCATT βCTCβCCTTβ GCCAGGAACC AGCAGACCAA 1500 CTGCCTTTTG TGAGACCTTC CCCTCCCTAT CCCCAACTTT AAAGβTβTGA GAGTATTAGG 1560 AAACATGAGC AGCATATββC TTTTGATCAG TTTTTCAGTG GCAGCATCCA ATβAACAAGA 1620 TCCTACAAGC TGTGCAGGCA AAACCTAGCA GGAAAAAAAA ACAACGCATA AAGAAAAATG 1680 GCCGββCCAG βTCATTGGCT GGGAAGTCTC AGCCATGCAC GGACTCGTTT CCAβAββTAA 1740 TTATGAGCGC CTACCAGCCA GGCCACCCAG CCGTββGAGβ AAββGGβCGT ββCAACGGβT 1800 GGGCACATTG GTβTCTGTGC GAAAGGAAAA TTGACCCGGA AβTTCCTβTA ATAAATβTCA 1860 CAATAAAACβ AATGAATβ
A69 Protein sequence:
Gene name: bone morphogenetic protein 7 (osteogenic protein 1) (BMP7)
Unigene number: HS.170195 Probeset Accession # : BE616633 Protein Accession #: NP_001710.1 Signal sequence : 1-30 Pfam domains: TGFb_propeptide [37-281] Transmembrane domains: none found Cellular Localization: secreted
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I I I I I
MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS 60 ILGLPHRPRP HLQGKHNSAP MFMLDLYNAM AVEEGββPGG QGFSYPYKAV FSTQGPPLAS 120 LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEGEAVT AAEFRIYKDY 180 IRERFDNETF RISVYQVLQE HLGRESDLFL LDSRTLWASE EGWLVFDITA TSNHWWNPR 240 HNLGLQLSVE TLDGQSINPK LAGLIGRHGP QNKQPFMVAF FKATEVHFRS IRSTGSKQRS 300 QNRSKTPKNQ EALRMANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEGYAAYYCE 360 GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSΞNVILKKY 420 RNMWRACGC H
Cervical
A70 DNA sequence Gene name : bone morphogenetic protein receptor IB (ALK-6) Unigene number: Hs.87223 Probeset Accession #: AA250737 Nucleic Acid Accession #: NM_001203 Coding sequence: 274-1782 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
CGCGGGGCGC GGAGTCGGCβ GGGCCTCGCG GGACGCGGGC AGTGCGGAGA CCGCGGCGCT 60 GAGβACβCGG GAGCCGGGAβ CGCACGCGCG GGGTGGAGTT CAGCCTACTC TTTCTTAGAT 120 GTGAAAGβAA AGGAAGATCA TTTCATGCCT TGTTGATAAA GβTTCAβACT TCTGCTβATT 180 CATAACCATT TGGCTCTGAG CTATβACAAC AGAGGAAACA AAAAβTTAAA CTTACAAβCC 240 TβCCATAAGT GAGAAGCAAA CTTCCTTβAT AACATGCTTT TGCGAAGTGC AGGAAAATTA 300 AATGTGββCA CCAAGAAAGA GGATGGTGAG AGTACAGCCC CCACCCCCCG TCCAAAGGTC 360 TTGCGTTGTA AATGCCACCA CCATTGTCCA GAAGACTCAG TCAACAATAT TTGCAGCACA 420 GACGGATATT GTTTCACGAT GATAGAAGAG GATGACTCTG GGTTGCCTβT GGTCACTTCT 480 GβTTβCCTAβ GACTAGAAββ CTCAGATTTT CAGTGTCGGG ACACTCCCAT TCCTCATCAA 540 AGAAGATCAA TTGAATGCTG CACAGAAAGβ AACGAATGTA ATAAAGACCT ACACCCTACA 600 CTGCCTCCAT TGAAAAACAG AGATTTTGTT GATGGACCTA TACACCACAG GGCTTTACTT 660 ATATCTGTGA CTGTCTGTAβ TTTGCTCTTG GTCCTTATCA TATTATTTTG TTACTTCCGG 720 TATAAAAGAC AAGAAACCAG ACCTCGATAC AGCATTGGGT TAGAACAGGA TGAAACTTAC 780 ATTCCTCCTG GAGAATCCCT GAβAGACTTA ATTGAGCAGT CTCAGAGCTC AGGAAGTGGA 840 TCAGGCCTCC CTCTGCTGGT CCAAAGβACT ATAGCTAAGC AGATTCAGAT GGTGAAACAG 900 ATTGβAAAAG GTCGCTATGG GGAAβTTTβG ATGGGAAAGT GGCGTGGCGA AAAGGTAGCT 960 GTGAAAGTGT TCTTCACCAC AGAβGAAGCC AGCTGGTTCA GAGAGACAGA AATATATCAG 1020 ACAβTβTTGA TGAGGCATGA AAACATTTTβ GGTTTCATTG CTGCAGATAT CAAAGGGACA 1080 GGβTCCTGGA CCCAGTTGTA CCTAATCACA GACTATCATG AAAATGGTTC CCTTTATGAT 1140 TATCTGAAβT CCACCACCCT AβACβCTAAA TCAATGCTGA AGTTAGCCTA CTCTTCTGTC 1200 AGTGGCTTAT GTCATTTACA CACAGAAATC TTTAGTACTC AAGGCAAACC AGCAATTGCC 1260 CATCGAβATC TGAAAAGTAA AAACATTCTG GTGAAGAAAA ATGGAACTTG CTGTATTβCT 1320 GACCTGGGCC TGGCTGTTAA ATTTATTAGT βATACAAATβ AAβTTβACAT ACCACCTAAC 1380 ACTCGAGTTG GCACCAAACG CTATATGCCT CCAβAAβTβT TββACβAβAG CTTGAACAGA 1440 AATCACTTCC AGTCTTACAT CATGGCTGAC ATGTATAGTT TTGGCCTCAT CCTTTGββAβ 1500 GTTGCTAGGA GATGTβTATC AGGAGGTATA GTGGAAGAAT ACCAGCTTCC TTATCATGAC 1560 CTAGTGCCCA GTGACCCCTC TTATGAGGAC ATGAGGGAGA TTGTβTβCAT CAAGAAGTTA 1620 CGCCCCTCAT TCCCAAACCG GTGGAGCAGT GATGAGTGTC TAAGGCAGAT GGGAAAACTC 1680
ATGACAGAAT GCTGGGCTCA CAATCCTGCA TCAAGGCTGA CAGCCCTGCG GGTTAAGAAA 1740
ACACTTGCCA AAATGTCAGA GTCCCAGGAC ATTAAACTCT GATAGGAGAG GAAAAGTAAG 1800
CATCTCTGCA GAAAGCCAAC AGGTACTCTT CTGTTTβTGG GCAβAβCAAA AGACATCAAA 1860
TAAGCATCCA CAGTACAAGC CTTGAACATC GTCCTβCTTC CCAGTGββTT CAβACCTCAC 1920
CTTTCAGGGA GCGACCTGββ CAAAGACAGA GAAGCTCCCA GAAGGAβAβA TT6ATCCGTG 1980 TCTGTTTGTA GGCGGAGAAA CCGTTGGGTA ACTTGTTCAA GATATGATGC AT
A71 Protein sequence 0 βene name : bone morphogenetic protein receptor IB (ALK-6) Unigene number: Hs.72472 / Hs.87223 Probeset Accession #: AA250737 / U89326 Protein Accession ft: NP_001194 Signal sequence: 1-13 5 Transmembrane domains: 128-144 PFAM domains: activin_receptor [30-111] , protein kinase [204-491] Cellular Localization: plasma membrane 0
MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED 60
DSGLPWTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD 120
GPIHHRALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPGESLRDLI 180 5 EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKβRYGEVWM GKWRGEKVAV KVFFTTEEAS 240
WFRETEIYQT VLMRHENILG FIAADIKGTβ SWTQLYLITD YHENGSLYDY LKSTTLDAKS 300
MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360
TNEVDIPPNT RVGTKRYMPP EVLDESLNEN HFQSYIMADM YSFGLILWEV ARRCVSGGIV 420
EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMβKLM TECWAHNPAS 480 0 RLTALRVKKT LAKMSESQDI KL
Bladder
A72 DNA SEQUENCE Gene name: Homo sapiens type II membrane serine protease mRNA 5 Unigene number: Hs.63325 Probeset Accession #: AA411502
Nucleic Acid Accession #: NM 016425
Coding sequence: 1-1314 (underlined sequences correspond to start and stop codons) 0
11 21 31 41 51
ATGTTACAGG ATCCTGACAG TβATCAACCT CTGAACAβCC TCGATGTCAA ACCCCTGCGC 60 AAACCCCGTA TCCCCATββA GACCTTCAGA AAGGTGGGGA TCCCCATCAT CATAβCACTA 120 5 CTGAGCCTGG CGAGTATCAT CATTGTGGTT GTCCTCATCA AGGTGATTCT ββATAAATAC 180 TACTTCCTCT GCGGGCAGCC TCTCCACTTC ATCCCGAGGA AGCAGCTGTG TGACGGAGAG 240 CTGGACTGTC CCTTGGGGGA GGACGAGGAG CACTGT6TCA AGAGCTTCCC CGAAGGGCCT 300 GCAβTGGCAG TCCGCCTCTC CAAGGACCGA TCCACACTβC AGGTGCTGGA CTCGβCCACA 360 GGGAACTGGT TCTCTGCCTG TTTCGACAAC TTCACAβAAβ CTCTCGCTGA GACAGCCTGT 420 0 AGGCAGATGG GCTACAGCAG CAAACCCACT TTCAGAGCTG TGGAGATTGG CCCAGACCAG 480 GATCTGGATβ TTGTTGAAAT CACAβAAAAC AβCCAGGAGC TTCGCATβCG GAACTCAAGT 540 GGGCCCTGTC TCTCAGGCTC CCTGGTCTCC CTGCACTβTC TTGCCTGTGG GAAGAGCCTG 600 AAGACCCCCC GTGTGGTGGG TGGGGAGGAG GCCTCTGTβG ATTCTTGGCC TTGβCAβGTC 660 AGCATCCAGT ACGACAAACA GCACGTCTGT GGAGGGAGCA TCCTGGACCC CCACTβGGTC 720 5 CTCACGGCAβ CCCACTGCTT CAGGAAACAT ACCGATGTGT TCAACTGβAA GGTGCGGGCA 780 GGCTCAGACA AACTGGGCAG CTTCCCATCC CTGGCTGTGG CCAAGATCAT CATCATTβAA 840 TTCAACCCCA TGTACCCCAA AGACAATGAC ATCGCCCTCA TGAAGCTGCA GTTCCCACTC 900 ACTTTCTCAG GCACAβTCAG GCCCATCTGT CTGCCCTTCT TTGATGAGGA GCTCACTCCA 960 GCCACCCCAC TCTGβATCAT TGGATGGGGC TTTACGAAGC AGAATββAGG GAAGATGTCT 1020 0 GACATACTGC TGCAGGCGTC AGTCCAGGTC ATTβACAGCA CACGGTβCAA TGCAβACGAT 1080 GCGTACCAGG GGGAAGTCAC CGAβAAGATG ATGTβTGCAG GCATCCCGGA AGGGGGTGTG 1140 GACACCTGCC AGGGTGACAG TGGTGGGCCC CTGATGTACC AATCTGACCA GTGGCATGTG 1200 GTGGβCATCβ TTAGCTGGGG CTATGGCTGC GGGGGCCCβA GCACCCCAGG AGTATACACC 1260 AAββTCTCAβ CCTATCTCAA CTGGATCTAC AATGTCTGGA AGGCTGAGCT GTAA 5
A73 Protein sequence: Gene name: Homo sapiens type II membrane serine protease mRNA Unigene number: Hs.63325 0 Probeset Accession #: AA411502 Protein Accession # : NP_057509 Signal sequence: none found Transmembrane domains: 31-53 LDLa domain: 54-94
75 Tryp_SPc domain: 204-429 Cellular Localization: plasma membrane/ER
_,-. 1 11 21 31 41 51
80 I I i i i i
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIW VLIKVILDKY 60 YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT 120 βNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDWEITEN SQELRMRNSS 180
GPCLSGSLVS LHCLACGKSL KTPRWGGEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV 240
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL 300
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD 360
AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT 420 KVSAYLNWIY NVWKAEL
A74 DNA SEQUENCE
Cene name: ESTs, Weakly similar to CCHU7L collagen alpha l(III) chain precursor [H. sapiens]
Unigene number: Hs.19322
Probeset Accession #: AA088458
Nucleic Acid Accession #: AA088458
Coding sequence: 862-1995 (underlined sequences correspond to start and .stop codons)
'1 11 21 31 41 51
I I I I I I
CCCCTTGGAC ACTGACATGβ ACTβAAββAβ TAβAATββAβ CACβAGGACA CTGACATGGA 60
CTβAAβAAAA AGGAGCTCGA GCAGGAGAAG GAGGTGCTGC TGCAGGGTTT GGAβATβATG 120
GCGCGGGβCC GCGACTGGTA CCAGCAGCAG CTGCAACGAG TGCAGGAGCG CCAβCβCCβC 180
CTGGGCCAGA GCAβAβCCAβ CCCCGACTTT GGGGCTGCAG GGAGCCCCCG CCCACTGGGG 240
CGGCTACTGC CCAAGGTACA AGAββTββCC CββTβCCTββ βGGAβCTβCT GGCTGCAGCC 300
TGTGCCAGCC GGGCCCTGCC CCCGTCCTCC TCCβββCCCC CCTβCCCTβC CCTGACGTCC 360
ACCTCACCCC CGGTCTGGCA GCAGCAGACC ATCCTCATGC TβAAGGAGCA GAACCGACTC 420
CTCACCCAGβ ACGTGACCGA GAAGAGTGAG CGCATCACGC AGCTGGAGCA GGAGAAGTCG 480
GCβCTCATTA AGCAGCTβTT TβAββCCCGC GCCCTGAGCC AGCAGGACGβ ββGACCTCTG 540 βATTCCACCT TCATCTAβTC CTTβTGββCC GCGTGGGCCC CCAGGβCCAβ CCTGGCACTC 600
AGCCCTTCGA GGGTGGGCGC CCCATCGCAC CCACCCTCTC TGβCTGGAGA CCCCCGGCAG 660
GCCCAGGCAC AGTCCCββAβ TβββCβCCTT CCTβCCβCCC TTβCCAβATβ βGCTCCCCAG 720
GCCTGCCCCC GGCTGβTCCC CGCACCβAGC GCTTGACTCC βTTTKββCTC CTGGTTGYTG 780
ACATGGGCTG GGGGCTCTCT TGAGTCCβCA TAGTCCβCAG CTACTACTββ CCGCTGTCAG 840
TGGACAGTGG GGTACCCCTC CATGAGTTAβ CGTCCCCCCβ TTTCCAβCGG TGCCGCCCTG 900
GGTCCCATCT TCAGGGAAAG GCACTGCCCA CGCCAββCTG CACTTCCAAC AACGGGCAGC 960
AGAGGGCGC6 GGGCGGCTCC GACGCGGGTC CAAGGGCAGC TTCCCGCTCA ACCAGGGCAC 1020
CAGGACGAGβ TββCTβTAGC TCGGACGGAC GGAAGTAGAT GGAGGGGGTG GGGACGGCCT 1080
GTAAGCGGGG GβTβCCTβCC TGGCTGGGGA GCCCCAGGGA TAGCGGTCGG ACTTCAβGTT 1140
CTGGCCAAββ CTβAβββACC CTCβCTGCAG CGGATCGGCA CGCCGGGTβG βCGAGAGCTT 1200
GβCCTβCATβ TGCCTCCCAC AGACCCTGGG GTGATGGCCT TCCCCCTCTT GGCCβββACβ 1260
TTβCCCCACG TTβAβTCCCA CACAACATCC TGTGAGCCTG GCTCCCCAββ AβββCCCCCA 1320
GACAGCTCCC AGGCACGTCA TAGβCAAAGC CTβTTTCCCC CGACTCAGGA TTTCCAAGGC 1380
CTGGGGTCCT GCTCACCCCC CTTTGCTCTC ACGCCCAGCC TβTCCCCAGG TTTCAGCTGG 1440
GAGAGGCCAC CTCCCTCAGC CAAGGAAAAC GAβAACCCCC AβGGTACAGβ AGGAGGCTGG 1500
GGCAGGTCCC CTTGGGTGTC ACTCCCTCAG CCCCTβCCCA GGCCCACTCC CGCTGGTGCT 1560
GGAGTACGCA CTGGTGGGGG GGCCCTGCTC AGCCCAACCT βGAGGGTCCC AGTGTCACCA 1620
GAACCACeee CACGGCAACA GCATCGATGG GTTCTGCAβC CCAGGGCCCC CGATGCGGGG 1680
TCAGTGTGTβ TGGG6CGCAG GGCCTCCGAT GCGGGGTCAG TGCGTGGGGG GCGCAGGGCC 1740
CCCGATGCGβ GGTCAGT6CG TGGGGGGCGC AGGGCCCCCT CGTGTCCAGG GCACTTTGGT 1800
ACACTGTCCC ACAAGGCACC TGTCTCAGAG GAGGGGCCCT GGCAGβCAβC GTGGCAACTC 1860
CCTTCCGGAG CCCAGCTCCA TβCTAACCTG CCCACAGCAA CCCCACAGAG CCACATTCCC 1920
TGCTGCACCT GGTCTGCAGG GβTβTCCCAβ βACAGGCCCA AβTCAβCCCA GCATGCAGCT 1980
GCCCTCCTAC CCTGAAGATG GGAGTGGGCT TTCCAGGGGA CATAAGGATG TCAGGCCTGG 2040
ACCTCCTGGG CAGβAAAGGG TGCAGGTCCT GAGGGCCTGT GCCCCACAGC CCCAβCACCC 2100
AGGTGGACTG CAGCGCAβTβ GGTβββCCAβ TGβCAGCCAG GGAGAAGCCC CCCGTCAGCA 2160
GGCTGβββTC TGCCCACCAG GGCCTCCCCA CGTCTGCCTT TGAGββTβCC TβCCATGCCC 2220
TGGGGGATCC TGGCATCTTT ACTGGACTGG AAGCAGβAβA CAβAACAβTG TCTGTCCCGG 2280
GGTGACTTCA TCAGGAGACC GCCCACATAG AGCTGGACCC CGCAGCTGAA GCGGAAATGT 2340
GAGACAGGCT GβCACCTCCβ GAAAAACTGC CTTTCAGCCT TGGTGTTCCG TGCAAGGTGA 2400
AAAGAAATAG βTCCTCCCAG TTTACAGCTT GAAATCAGGC TAGTGAGTGG CCCTGGAGAC 2460
CACGAGGGGA GAATTTAAAG GCCCCGβCTβ βCAGGβTCTA GGTGGCTββC AGAGGCACAT 2520
GCAGACCCTG CCTGGAGCCT GCCCTAGGAC GCTGGGCβββ TCAGTCTCCG TGCAGGATGT 2580
GAGCAβCβTC CCTGGGCTCT ATCCGCGAGG TGCCAGTAGC GTGTGCAGGT ACATACACGT 2640
GCβTβCACAC TGTGATGACA CCCGGAAATG TCTCAGGATG TTGAAATGTG TCCTTGGGGG 2700
CAGAAβTβTC CCCAGTTGAG AATCTGCCCC AGAGGAACAC ACCCACACCA GGCCTCAGGA 2760
TTTTGTGTTβ ATCAAβTTCC AAβGAAAAGG AACATCTCAG CCGGGCGTGG TββTTCACGC 2820
CTGGAATCCC AGCACTTGAG GCCAGGAGTT CCAGAGCAGC CTGGGCAACG CAβTβAGAGA 2880
CCCCATCTCT ACAARAAAAA AAAAAGAAAG AAAGAAAATG AGAβATCCAG GTTTAAAAAT 2940
TCATAAACAC CACAAGGAAA CAATACACTA TGAGACCCAG CAGAAGCAAC AβATTGACTC 3000
TAGACCCA6A TACTAGAATT ATCAGAGAGA ATATAAAGTA ACAGTGTTTT ATATATCTAA 3060
AβAAATAAAA GAGATTTCTG GAAACATGAA AAAAAA
A75 DNA SEQUENCE
Gene name: SCCA2 or 2b, serine (or cysteine) proteinase inhibitor
Unigene number: Hs.227948
Probeset Accession #: AB035089
Nucleic Acid Accession #: AB035089
Coding sequence: 9845-10219 (underlined sequences correspond to start and stop codons) 1 11 21 31 41 51 I i i i i i
GββCATβCAβ CCATCGGGGA AAATCCATAG TGCAGATAAA βCAAGGAGGA AGAAGAAGβA 60
CAβTTCTAβT AAAAGGGAGA ACATCAATAT AGβATGTTTC TTAGCAATAG AAAAAGAAGG 120
CCAAβAβGAA TTAGββAGAG AβTTATAAGA GATCAβCAAβ GGGACAGGβT TAβATTTGGT 180
TTGGTTTGAA AGCATACAGT AAATATGATG TCTGTCCCTG GCAGTGTTGG CAGAGTAGGA 240 AGGAGGAAββ GAGGCAAGAG ATAATATCAT TTTCTCTGTG CTCCAACTGT ACTTACATAT 300
GAGACTATTT CCCTCTCTGC TTTTCAAACC TTACTβGAGT TGTTTTCCCT CATGAAAACC 360
AAGAAAGGAA AGCTAGTTAG TCTTGTTCTG AGGTTGTTCA ATGTATACAT ATCTATATCT 420
GTAGACA6AA TCCTTGGGAA TACAGTAATT GACATATATT CTGTTATTTG ATGCTTGAAA 480
AATCTCCTCC ACTAACCAGT TTCCCTATAG ATTGCCACAA GCACATAATA ACAAACAATA 540
AATAAAATCT TCTCTTβACT TTGTTACTTA ACAATGCTGA GAAAACTTTA CAGCCTTCAT 600
AAGGAAGTGA GGTCCAGGAA AATCTAGGAG ATATTTCTTA ACCAATCTAT AAAGGCATTA 660
GTAATGACAG GATATTTCCT GAAAGTGTAA TTTCCCATTG AGGATTTβTT TTTAATTTCT 720
GGATTCCTGG AGCCAATGAA GTTGGTGTAT GTTTATGAAA TATCAAGAGA CATAAGTTGG 780
CAAGTGTTCA TATGCAAAAA CTTCTTGGAA TTTCTGAGTT CTCTGTGGCA ATATATGACA 840
TCAGGATATG TCCAGTCTCA CACACCAGGA TATGTCCTTT CTAGCCTβTC TATCACATGC 900
TAGGAGAACT ATTTAGGAAC AGAAAAAAAT GCCTGAAATG ATTTCTCATT TGAACTCATC 960
CAAGCTTTCT CTAAATTTAA GCAAACTCCT GGTCATTTTC AGTTAGTACC TTTCCTTAAG 1020
TTCAACCTTC AGGGCAAACC TCCGTGCCTC AGACGTTTAG CCATAGTCTG AAATTCTCTT 1080
CCATAGATTβ GTCCCCTGTA ACCCCGGTTT GTCTCAGCTT GTTATCCTGT TTTTTTCTTC 1140
CCTCCATTCC CAGGATGAGC TTGTTGCTTC TGTCCTATGA GACATTAGAT TCCTTTTCTT 1200
TGGTACCCGA GTAAATCCAT CCTACTCCAA TAGAGGAAGG TCCATTTTTG TCTTATAGCG 1260
CTGGATGCAG ACTCAGCTGA GAAGACCATT ATTCATTTTT GGAATTCTTT ATCTCAGATA 1320
TTTCCTCTTC TTXCTTTTTC TTCTATCTTT GGATTTTTAG TCCATCAACG CCCCATTAGT 1380
CTATTCCCCG ACTTCAATCA GGGAACTTAT ACCTCTTAAA CTCATTCAGA GACTCAAAAC 1440
ATATATATTG ATACAGGAGA CCTAAGAAGA GCATGTCTTG GGGGTTGAβG AAACAβGCAβ 1500 βTβAGAAATT TCCAGATTGG AAACACAGCT TCCTTTCTCC CATCCAGCCC CTACTTTCAβ 1560
CCTATGTGTT TCTGβCACCT TβTTβTAGAT AAATCTCCCT TGACTTTGTG ATGTGCTGAG 1620
AAAACAAACT CACGβCTCβT GTTAAAAAββ βCCCATGACA ATACCAAGTG TTGGGGAGAA 1680
TGTGGAGAAA TCAGAACTCT ATTCACGGTC GβTTGGAATG CACACTTGTG CAGAATTCTA 1740
TGGAGAAGAG TCTGGCATTT CCTCAAAATG TTAACCTGGA TTTACCATAT GACCCAβCGA 1800
TTTCATTCAT AGGTTTATAC TCAAAAGAAA TGAAGAAATA TGCCATGCAA AAAAATβTAC 1860
ATβAAAββTC ACAACATCAT TATTCATAAT AGTAAAAGβA TGGAAACAAC ACAAATGTCC 1920
ATCAACTTAT GATTAAAGAA AATCTGGTCT ATTCATAGAA TGGAATATTA TTCGACCACA 1980
AAAAGGAATG ATGTACTGAT CCATGCAATG ATGTGGACAA ACCATGAAAA TAACACTAGA 2040
TTAAAβAAβC CAGTCACAAA AGGACTTACT GTATGATTCC ATTTACCTGA AATβTTTββA 2100
ATAGGCAAAT CCATAGAAAC AGGAGGTAGA TTCCTGGTTT CCAGββTCTC CAββAAGGGA 2160
AβAATβAAβT ACAAβATTTC TTTTβGAGGT AGTβAAATTG TTβTGGAATG AGATCATGAT 2220
GATGATAGCA CAACTTTβTG AATATAATAA AATCATTGAA TTGTACAGTT GAATTTATGG 2280
TATATAAATT ATATGTTAAT AAAAAGGGGG TCCACAAAAC AAACAGCCCC CCACTCTGGT 2340
TGTCAGββAG ATATTGGATT AAATGGCCTT GGACAACAAC CCCTCTCCCT GGCCACAGAC 2400
ATTCTTCAGA TTACAAβATA TTCCAGGβGA AACACTGGAA TGAGTCTGAA GCCAGGTGCT 2460
AAACAGAAGG ACCATTGAGA AATGTTGTβA TCCTGACAGG TCAAGCAATT TATTTTTCGG 2520
CTTCATTTTT AAATGTAAAA TTAGAAAGCT GCCATTTAAA ATGβCCCβTC TβTTTCAATT 2580 βCTCTTCTCA GTGTCAGCCT GTTAACTCAA TGTGTTAGTC TGTTTTCATG CTGCTGATAA 2640
AAACATACCT GAGACTGGCA AGAAAAAGAG GTTTAATTGG GCTTAβAβTT CCACβTGATT 2700 ββGGAββCCT CAGAATCACA GTAGGAGGCA AAAGTTATTC TTACATGGTG GCTGCAAGAG 2760
AAGATGAGβA AGAAGCAAAA GAAGAAACCC CTGATAAACC CATCGβATCT CCTβAGGCTT 2820
ATTAACTATC ATβAβAATAG CACAAGAAAG ACCGGCCCCC ATGATTCAAT TACCTCTACC 2880
TGGGTCCCTC CAATAACATG TGGAAATTCT GGTAGATACA ATTCAAGTTG AGATTTGGGT 2940
GGGAACACAG CCAAACCATA TCACTCAGCA AGGCAGATAA CTTTCTCACT GAGCCTATGC 3000
AACAGAAAAC CATCTGββAT GGTTGTAAGG GGCACAβGAA βTGACTGGTA GGATCACTGC 3060
CAAAGCTGAG CACTCAGGAβ AAGGCAATAG AATCCTATTC TCCATAGTAT GCTATAAGAT 3120
ACTGAAGTAC ACTTCTTCAC TATCTCTTTG βACTTAGAAT TAGCACTACA TTCCTTGTTA 3180
TACAGAAAAA TTACTAAβGA AATTCATAGG ATGACAAAAA CTTTCAGAAC TGAAAAACAG 3240
GAAATGTAAG CTTTTTAGTT CTTTGGTATT CGAAGTATGC CTAAAAGACA ATGCAAAATC 3300
CAAGAAAAGA ATGGTGGGβT TTTTβTTTGT TTGGTTTTGT TTTTGTTTTA CAGCTGGAGT 3360
AGAATACAAA GGGATGGAGT TGAAACAAAT GAGAGGAAAT TGGAATTCTA AACTTATTCT 3420
CATTGβCATT AGAAAGGCAC CTACATGTAT TTCACATGAG CCGGTGACTG CTGACTTGCA 3480
TTCTTATTTT TTCCCTATAG ATTAAAAAGG AGGTACAATG GTAGAACTGT AATCCTGTCC 3540
TTTGTCATAA ATTTTCATAT TCATAAAGGT GAGTGTTAGC CCGCTTGTβA AATCTGAAGT 3600
TGAGTAACTT CAAATACTAA CCACAGAGGG AAAβGCAGCA AβAβGAGAGG CATAAATTTA 3660
GGATCTCACC CTTCATTCCA CAGACACACA CAGCCTCTCT GCCCACCTCT GCTTCCTCTA 3720
GGAACACAGG TAAGAGCTTC AAGCCTCTCC AGCTTAATAA CATGAATTAT TTTTGAGAAT 3780
AATAATGATA CTGTGTTCTA TATCATGCAT CTCCTGCATT CTGTCTGATT ATATTTTACT 3840
TATTCTGCCA GAGCAAAATT AAAATACCTA TTTCATCTGA TTTGTCCTTT ATCTAAATTG 3900
CTTAβTTCCA AGTAAACCAA GGCACTTTTA GGAACACAGA GGGAGAGTGC CTTGCAβCCA 3960 βAβAGTCTTG AAGGAGATGT CAGGGACGCA TCTTAACAGC TGGTTGGATG TGATCCACAG 4020
AββTCTCCTG TTAGCATTCA TTGTAAAGCC ATCCTACCTA GCTCTAGTGT AACCAGCAAT 4080
GAAAGAAAGA TAAAGAββGT CβATTACTTA TTTACAATAG TCTTTAAAAA CGTAGTTTTG 4140
TAAGCCTTCT AATTAGGACA TTAATATATT TAATATATGC ACATTGTAGA AAGATTGAAG 4200
CGTTAAAAAT AAGAGAAAAA CTTTAAATGT CAAAATCTCA CAACCCAGAT ATATCATTTC 4260
TTTAAGAAAA TTGTACTACA AAATACCATT CCATTTATTA AAGTCATTCT GACAGGAATC 4320
TGATβCTTTT CCAββAGTTC CAGATCACAT CGAGTTCACC ATGAATTCAC TCAGTGAAGC 4380
CAACACCAAG TTCATGTTCG ATCTGTTCCA ACAGTTCAGA AAATCAAAAG AGAACAACAT 4440
CTTCTATTCC CCTATCAGCA TCACATCAGC ATTAGGGATG GTCCTCTTAG GAGCCAAAGA 4500
CAACACTGCA CAACAAATTA GCAAGGTAGC TATCAGCATC ATTACGTTGT CCTGTTGCAG 4560
TTTTTCTCTG GTTCCGTCGG CTAGCACGCA GATGβTAATA GATGTGGTGG TCTGATβββT 4620
AβCACAGGGG GCTGTGCAGG AATTCCCATA ACTGTβAGAC CACTGACTTA AACAGATCTT 4680
TTβAGTAAAG TTTTCTTβTC CCGCTTCATG TCTCTTCCAG GTTCTTCACT TTGATCAAβT 4740
CACAGAGAAC ACCACAGAAA AAGCTGCAAC ATATCATGTG AGTCACAGAG CACTCTGATT 4800
CAGCTTTAGA TCCCTGAACA GGTCATAGTT TAAACCTGGA ACTTCACAAA AACTAAGAAA 4860
AGGCCAGTTT TAGGGAAAAT CTTGGACACA AAGATTGAGA CATACAGAGT GββTTβGCAT 4920
TTCATGGCAC ATAATTATTA TTCCTCATTT CTGCβTTACT AAAAβACAGT CAGCACTGTA 4980
CCTCAGAGCA TAGGTCTGGA TCAGGATAGG CTβGGTTCAG ACTCCAβCTT TGCTCTTCAC 5040
AAATGATGAA TAAGAGCAGβ ACACAACTGC TCGGAGTCCC AGTGACCTCA TCCCAGAAAA 5100
CTAAGQ3TAA GAAAAAATCT GACTCAATAC ATGCAAATAC ATGCAAATGT TTACAACAGT 5160
GCCTTGCCCA TAAAAGTCAT AATAAATGTT ATTATTATTA TAAAGTAGCT ATAATTATAC 5220
TAATCATAAT AATGTGAAAA TAATTTAATT TTCATTGAGT CATTAATGAG ATTCAGAGGA 5280 ATAAGCACAA GTCCAAGTAT ATTTTGGAAA ATGATTGCTA TGGAATATAT TGGTTTAGAG 5340 CCTTAATAGT GCAAAATGCT TTGCTGGAAG GTAGAAAGTT CTAGATTTAA ACAGGCTTAG 5400 GTTCAAAACT TGGCACTTCT AATTTATGTC TCTATAAACA GGGTTTTTTT CCCCATTCTC 5460 TGAGCTTTCT TCTGTTCATC TGAATTGAAC TAAAGACTTA GAβTTACCCA TGTAAAGTCC 5520 TTAGCCATββ ACCTGGCATA CACTCTTCTT ACGTGCAGAβ AATβACCATC ATGAGGAAAG 5580 AGCCACAGAT CAGTCAATGT GTCCTACAAG ATAATACCAC CAACAGGTAT AACAGGGCTT 5640 CCTGGCATAA TCTATTTAAA ATATCCAACC TTCAACATAC TCGTATCCTT GATGACTGTT 5700 AGAAGTGAAA TATGGTCCTT GCCCATAAGβ AGCTGAGAGT TTAACTGGGA AGCTAAACCT 5760 AACCCTTTAA ACCAACAAGG AGAAAATCTA CTβGTAGACA GCGCTGCATC TTTAGTTCAG 5820 AAGAGAAAAG ATTGCAGTAC βTTAβAGCAA GAAβAATTTT CTGGAAGAAG TCAAATATAA 5880 GGTGβATTTT GAAGβGTATT TGAGGT6AAA TACACCAATT ATCAGGGAAT AACATCAAAG 5940 GTCCTCAATG AβACTACCAG CATTTAG6GA CTGATCTAAC AβACTTAGCA TβββTTTAβT 6000 ATTTACATTβ ATACAβCAAT TβAATGATCT CCTTTTTTGA TGTTTGAAGG TTGATAGGTC 6060 AGGAAATGTT CATCACCAGT TTCAAAAGCT TCTβACTGAA TTCAACAAAT CCACTGATGC 6120 ATATGAGCTβ AAGATCGCCA ACAAβCTCTT CGGAGAAAAG ACGTATCAAT TTTTACAGβT 6180 AATTTCACCT ββCCTACCCA CATTTCATTT βCATCCTCAT GTCTGTGTCT CTGAβTββCC 6240 AAATGGAAGA AAGCAAββCA βATβAβCCTG GCCGACCCAG GTGGAGAGCA TTTACTCAβA 6300 βTβCATTACC TCCATTTCCA CAACTCTCCC CCACTGGAβT GTCCCAGACC CCAACGATAC 6360 ATCACTGAAG TβTββATTTA GGβATAATCT TβTGATAAAA GAGGAGGTTG TGTAATAGAG 6420 TGAGTAAβAβ TAATAAβTAA TAAβATACCA TCCATAAACT GGCACTGACT CAGTCACATA 6480 CGATACATCT TGGTβGGAAA TβTATβACTA ATGGGATATT ATTGGAATGG GCAGGCTTββ 6540 GTGAGTTCCT GAGAATAGTT GAGGAAGTAC CAGGAAATAT TGAATGCACA GβATβAAAGA 6600 CAAAAACAAA GATCAGAAAC ATCATGGTTA AAATTACTGG AβAGAAGTCT GAβAAGCAAT 6660 GAATCTCCTT CAGGGAAGCC TGCTCTGCAG TTTGCAAACC ACAGCCTCTT CTGCTTCTGC 6720 CTTTTGCCAA GATβATATTG ACCTTCAβTβ ACCTCTTTCT TβTGCCAGCC CACATTCCCC 6780 TTTTGCATTG CCTACATGAC ACCTGTATAA AAATATCCAT GGACAGGAGA TACTGCATCT 6840 ATTCAGGGTC TGGATTCAGC TTACTβTTβT TACAAATAAG TAAGTTTGGT AATATATAβT 6900 TACATAAATT ACTCCTAATT CCTACTTCTT CCTTCATATC TCAAAGGAAT ATTTAβATGC 6960 CATCAAGAAA TTTTACCAGA CCAβTβTβGA ATCTACTGAT TTTGCAAATG CTCCAGAAGA 7020 AAGTCGAAAG AAGATTAACT CCTCββTGGA AAGTCAAACG AATGGTAGGA GAGCCACCCA 7080 TTATAGAAAC ACCTTTGAβA AACCTATGCC AGTGAGCCTT GTGCTTGACA CTGCATGGβG 7140 GAACAGGTGT GGGGATTGAG ATGGGTTTGC AGGGAGGGCT GAAGAGββCA CTCCAβATGA 7200 AGGATTTGTC CAAATGAATA TGAAGAGAGC CTAGGGGAGC CAAGGAGGAA ATCACAGGAA 7260 GCCAATTAGA TGGAAACACA TCTGGAGAAT TATTTGCTTA TGGCCCTβCA TGACAATAGC 7320 TTTGTGGATC CCCTGTCTCC GCTCAGACCT ATTTTGAGAT CATATCCTTT ACTTTAAATC 7380 AGACTCAAAT TTTTATGATG AATATTTAAT AGAAAACATT AGAAAGCGTC TCTCGTCTCC 7440 TTTACTAATT GGGAAACAAG CAGCTCTCTβ GTAAATCACC CTTTTGTCTC TGAGCTGGAG 7500 CTGCCTGGAT CACATCTGTA GCCAATGTGT TCTGCAGββA TTATCACAGC TCTCTTCCCC 7560 ATCAAGGGCA AAGAGCTTGA CAAAGTCTCC ATTCTACAGA CATCTTTCTT ACCTCCCACC 7620 TCTCATTACA GGCCAAACTT ACAGCAACTC AACATGAGAG TGAATAGGAA GATACCCCCG 7680 GAAGTAGTGT CTGACAGCAC AβGACATGCG TTTCATATTA CAGAGCTCAA GTCACTCATC 7740 CTAAAATGCA ATCAGGGCCT CCTTCCTCTG AATGGGGACC CCGTAGTTAA AAAAAAATAA 7800 AAGTAGGAAG AGGAGGGAGG GAGAAAGGAA AGACACATGT TGGAAGAGTA GACAAAATCA 7860 GTTTATCAGT ATTCCAAATC AGATGATTGG AGACATTCAT ACACAGAGAA CβTβAACTCC 7920 TTCTCTATCA CAAGAAGTGA TGTCTCCATC AAGGGTAACT TTATACGACT GβAβCCTTGA 7980 AGAAAGCTGC ATCTGGTGAA CCACTGGTCA GTGAGTCTAA CAATTCAAAG ATCAAAGTCA 8040 GTGAGTCTCA AGCAGGGATT TGGGTCAATA ATTAACGATC AGTCACβAAC ATTTGCAAAG 8100 CATCTTCCAG ACAAGCCATT TGTAGCTTGT GTAAAAGACT CTTTTATTCT TTCCCTTGCA 8160 GAAAAAATTA AAAACCTATT TCCTGATGGG ACTATTββCA ATβATACGAC ACTGGTTCTT 8220 GTGAACGCAA TCTATTTCAA AGGGCAGTGG GAGAATAAAT TTAAAAAAGA AAACACTAAA 8280 GAββAAAAAT TTTGGCCAAA CAAGGTATTG TCTATATTTT ATTTATATAG TβTAATATGT 8340 TAATACATGG AATGTTAAAC ATTTCTGATG GAATGTAACA TβATAAGTAA AAAATAAAAA 8400 TTGTTCATGT CTGTTATTTT GTTGTTTTAC TCTTATAACT TTATTTAGTT AGGAATACCT 8460 GAAAAACTAT TGTTTCTAAC TCATGβAATT CCTGGGTTAT TTCTTAGAAG AAGAAGGATG 8520 TGTTGCTATC TCAATAATAT TATCTTTTTT GTCTTGTGTT TCACGTGTTA TTTGTTGβAC 8580 ACATTGATTT ATTGCAβAAT ACATACAAAT CTGTACAGAT GATGAGGCAA TACAATTCCT 8640 TTAATTTTGC CTTGCTGGAG GATGTACAGG CCAAGGTCCT GGAAATACCA TACAAAGGCA 8700 AAGATCTAAG CATGATTGTG CTGCTGCCAA ATGAAATCGA TGGTCTβCAG AAGGTAAGAA 8760 CTTGCATCTA CAACTCTTCC TTCTACTGCC βGACATTTTT CCAAAGATAC CAAGTTTAAA 8820 CAAGGTAAAA GCTTATGACC GAβTTβCCTC AAAATGATGA AAAATTCTAA ATGAGGAATβ 8880 ATGACTCACC TTCATATTAC AAATATTTGA GCATAGGGCC TβACACAAAC TGAAAGCTTA 8940 GTTTTTGTTT GTTTβTTTGT TTTTATTATT ATTATTATAA TACTTTAAGC TTTAGGGTAC 9000 ATGTGCACAA TGTβCAGGTT AGTTACATAT GTATACATGT GCCATGCTGG TGTβCTβCAC 9060 CCATTAACTC ATCATTTAGC GTTAGGTATA TCTCCTAATG CTATCCCTCC CCCCTCCCCC 9120 CACCCCACAA CAGTCCTCAG AGTGTGATβT TACCTTCCTG TGTCCAAβTβ TTCTCATTGT 9180 TCAATTCCCA TCTATGATTT AATTCCATCT ATGGCTTAGT TAATGATTAA TTTATTAGAG 9240 TTACATGCAT TGGATATCAA TTTGATGATA TTATTATGCA GCAATTTAAA CTTGACTGGG 9300 AGAAATATAT ACCAATGTGA GGAAAGTTTA CAAATAGGCC GAGTAGAAAA GGGAATACAA 9360 ATTTAGGAAT TTAGGGAATT ACAATTTAAT AATTGCAATG TGTACTAAAT AATGTATACA 9420 GAAAAATATG ATGAGCCTAT TAAAAATTGA CACATGTAGT AGGCTGTTGβ CACAAGAAAT 9480 AGTGATACAT ACAGTTCATT GTβTACAAAA TAATGTAATC ATATTTTACA TGTGTATCAT 9540 ACAGTTGTAT ACATACATAT GTACACATAT ACATATACGT AAAAACATβA TTCTGTTTTT 9600 ACATACATGT ATATACATAT ACACATATAA CCCAATGTAT TTATATATTC AGGACTCATA 9660 TTTTACCTAT TAGAATAATA ATGTCTATTA AAβTβAACCT TCTGTATTTC ACATTTATTG 9720 CCAAAATAAC GAATCTCCAC ATAβTCAATT CATTβTTAAβ GTGTATTAGA βATCGACAGT 9780 TAGTCATATC AGTTTCTTTT TTCCATTTGT ATAGCTTβAA GAGAAACTCA CTGCTGAGAA 9840 ATTGATGGAA TβGACAAGTT TGCAGAATAT GAβAβAGACA TGTGTCGATT TACACTTACC 9900 TCβGTTCAAA ATGβAAGAGA βCTATGACCT CAAGβACACβ TTGAGAACCA TβββAATGGT 9960 βAATATCTTC AATGGGGATG CAGACCTCTC AGGCATβACC TGGAGCCACG GTCTCTCAGT 10020 ATCTAAAGTC CTACACAAGG CCTTTGTGβA GGTCACTGAG GAGGGAGTGG AAGCTGCAGC 10080 TGCCACCGCT GTAGTAGTAG TCGAATTATC ATCTCCTTCA ACTAATGAAG AGTTCTGTTG 10140 TAATCACCCT TTCCTATTCT TCATAAGGCA AAATAAGACC AACAGCATCC TCTTCTATGG 10200 CAGATTCTCA TCCCCATAGA TGCAATTAGT CT6TCACTCC ATTTAGAAAA TGTTCACCTA 10260 GA6GTGTTCT GGTAAACTGA TTGCTGGCAA CAACAGATTC TCTTGGCTCA TATTTCTTTT 10320 CTATCTCATC TTGATGATGA TAGTCATCAT CAAGAATTTA ATGATTAAAA TAGCATGCCT 10380 TTCTCTCTTT CTCTTAATAA βCCCACATAT AAATGTACTT TTCCTTCCAG AAAAATTTCC 10440 CTTβAGGAAA AATGTCCAAG ATAAGATGAA TCATTTAATA CCGTGTCTTC TAAATTTβAA 10500 ATATAATTCT GTTTCTGACC TGTTTTAAAT GAACCAAACC AAATCATACT TTCTCTTCAA 10560 ATTTAGCAAC CTAGAAACAC ACATTTCTTT GAATTTAGGT GATACCTAAA TCCTTCTTAT 10620 GTTTCTAAAT TTTGTGATTC TATAAAACAC ATCATCAATA AAATAATGAC ATAAAATCAT 10680 TTTTGCTTTA CCTβTTTTCT CTCTβGAAAG GGCAAGTβTC CAGTTACACA TAGβAAAβAT 10740 AATTTAGAGA TATATTAATC ATATATAAAG βAAAATTAAA AACAGAGTAG TTCATGATGA 10800 GCCTGGAGTA GAAGGCATAT CCCAβAACAβ GAβGAGCCTT GTAAACCACA TAGGAACTTC 10860 CTATTTTATG CTAAAGGGAT AAGAAACTCA TTACAGGCTT TGATGGTTGT TTGTCAAAGA 10920 GGGGCATAAA ATTATCATAT CCACATCTAG AAAATACATC TCTββCTACG CTGATATCAA 10980 TGGATGCGAG GAAAGAACAG TGTGGTTACC ATATATAAAT TAGGAAATCA TTAGAGTATT 11040 GGGAGTGGAA ATGGAGAGAA AGAAAGAGCC TGGGGGAATT ATTTAGβAAA TAATAGTTAC 11100 AGAAAβACAT CTAAβTTGCT GACCTATCTG ACTGGAT6GA TGGAAGAATA TCTTGTTTCT 11160 GAGAGAAAAA AAGACTTTGG GTTTAAATTT βTACTTGATG AATTAAGGTA CTTTTAATAT 11220 TCAAATGGAT TTGCCTββCA GGCACTTβAA βATATTAβTC TAAATCTCAG AAACAGAATA 11280 TGATCTGAAG CTCTAAATTT GTGATATTCA ATATAAATAC TTTAGAGTCA TTGGGATAAA 11340 TATGGTAGTT βTAβCTAAAA βCAAAAATAA GATACTAGGG AGAAAββATA AAβTTAβAAβ 11400 AAAGAAGAAT CTAβAATTGA CCTTGAAGTA TATCAGCATG TGTAAA6ATC AββAATTβAT 11460 CATTTTTATT TTCCAβAAAG TAGCTTTTCT TAGGGTTCCA TATTTACTCC CATAGATTCT 11520 TCCC
A76 Protein sequence:
Gene name: SCCA2 or 2b, serine (or cysteine) proteinase inhibitor
Unigene number: Hs.227948
Probeset Accession #: AB035089
Protein Accession tf: BAB21525
Signal sequence : none ound
Transmembrane domains : none found Serine Proteinase Inhibitor domain:
Cellular Localization: secreted
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M INSLSEANTK FIMFDLFQQFR KISKENNIFYS PIISITSALGM VILLGAKDNTA QIQISKVLHFD 60
QVTENTTEKA ATYHVDRSGN VHHQFQKLLT EFNKSTDAYE LKIANKLFGE KTYQFLQEYL 120
DAIKKFYQTS VESTDFANAP EESRKKINSW VESQTNEKIK NLFPDβTIβN DTTLVLVNAI 180
YFKβQWENKF KKENTKEEKF WPNKNTYKSV QMMRQYNSFN FALLEDVQAK VLEIPYKβKD 240
LSMIVLLPNE IDβLQKLEEK LTAEKLMEWT SLQNMRETCV DLHLPRFKME ESYDLKDTLR 300
TMGMVNIFNG DADLSGMTWS HGLSVSKVLH KAFVEVTEEG VEAAAATAW WELSSPSTN 360 EEFCCNHPFL FFIRQNKTNS ILFYβRFSSP
A77 DNA SEQUENCE Gene name: hypothetical protein FLJ13459
Unigene number: none found Probeset Accession #: XM_047266 Nucleic Acid Accession if: XM_047266 Coding sequence: 485-1471 (underlined sequences correspond to start and stop codons)
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I I I I I I
CTGACCTCAA GTGATCCACC CACCTCTGCC TCCCAAAGTG CTGGβATTAC AGGTβTβAGC 60
CACCATGCCA GGCCCTCTTA ACCTCTTCAA GTCTGTTTTC TCATCTβCAA AACAβAββTA 120
ATAAGATCAG TATCTTCTTA ATGβAAβCAC CTGGACTACA TTTTTTTCAT TCATTGTTAT 180
CATAAATGAG GACTAACCTG TCTCCCGTTG GGAGTTTTβA ACCTAGACCT CATGTCTTCA 240
TGACβTCATC ACTGCCCCAG GCCCAGCTGT GTCCCTACAC CAGCCCCAGC TGACGCATCT 300
TCTTTTTCTG CCTGTAGAGA TβGTTACAAT GCCTGGCGTG ATGCATTCTG GCCTTCGCAG 360
ATCCTGGCGG GGCTGTGCCA ACGCTGTGGC CTCCCTGCCC CTGAATACCG AβCCGGTGCT 420
GTCAAGGTGG GCAGCAAAGT CTTCCTGACA CCACCGGAGA CCCTβCCCCC AGGGATCTCT 480
TCACATGTGG ATTGACATCT TTCCTCAAGA TGTGCCTGCT CCACCCCCAG TTGACATCAA 540
GCCTCGGCAG CCAATCAGCT ATGAGCTCAβ AβTTβTCATC TGGAACACββ AββATβTGGT 600
TCTGGATβAC GAGAATCCAC TCACCGGAGA GATGTCβAβT βACATCTATβ TGAAGAGCTG 660
GGTGAAGGββ TTGGAGCATG ACAAGCAGGA GACAGACGTT CACTTCAACT CCCTGACTGG 720
GGAGGGGAAC TTCAATTGGC GCTTTGTGTT CCGCTTTGAC TACCTβCCCA CβGAGCGGGA 780
GGTGAGCGTC TββCGCAGGT CTGGACCCTT TGCCCTGGAG GAGGCGGAGT TCCGGCAGCC 840
TGCAGTGCTG βTCCTCCAGG TCTGGGACTA TGACCGCATC TCTGCCAATG ACTTCCTTGG 900
ATCCCTGGAG TTGCAGCTAC CAGACATGGT GCGTGGGGCC CGGGGCCCCG AGCTCTGCTC 960
TGTGCAGCTβ GCCCGCAATG GGGCCGGGCC GAGGTGCAAT CTGTTTCGCT GCCGCCGCCT 1020
GAGGGGCTββ TGGCCGGTAG TGAAGCTGAA GGAGGCAGAG GACGTGGAGC GGGAGGCGCA 1080
GβAββCTCAG GCTββCAAGA AGAAGCGAAA GCAGAGGAGG AGGAAGGGCC GGCCAGAAGA 1140
CCTGGAβTTC ACAβACATGG GTGGCAATGT GTACATCCTC ACGGGCAAGG TGGAGGCAGA 1200
GTTTGAGCTG CTGACTGTββ AGβAGGCCGA βAAACGGCCA GTβGGβAAGG GGCGGAAGCA 1260
GCCAGAGCCT CTGGAGAAAC CCAGCCCCCC CAAAACTTCC TTCAACTGGT TTGTβAACCC 1320 βCTGAAGACC TTTGTCTTCT TCATCTGGCG CCGGTACTββ CGCACCCTGG TβCTGCTGCT 1380
ACTGGTβCTG CTCACCGTCT TCCTCCTCCT GGTCTTCTAC ACCATCCCTG GCCAGATCAG 1440
CCAGGTCATC TTCCGTCCCC TCCACAAGTG ACTCTCGCTG ACCTTGGACA CTCACCCAGβ 1500
GTGCCAACCC TTCAATGCCT βCTCCTββAA GTCTTTCTTA CCCATGTGAG CTACCCCAGA 1560 GTCTAGTGCT TCCTCTGAAT AAACCTATCA CAGCCACTG
A78 Protein sequence:
Gene name: hypothetical protein FLJ13459 Unigene number: none found Probeset Accession # : XM_047266 Protein Accession #: XP_047266 Signal sequence: none found Transmembrane domains : 291-313 C2 domain: 27-86 Cellular Localization: plasma membrane / ER
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I I I I I I
MWIDIFPQDV PAPPPVDIKP RQPISYELRV VIWNTEDWL DDENPLTβEM SSDIYVKSWV 60
KGLEHDKQET DVHFNSLTGE GNFNWRFVFR FDYLPTEREV SVWRRSβPFA LEEAEFRQPA 120
VLVLQVWDYD RISANDFLGS LELQLPDMVR GARβPELCSV QLARNGAGPR CNLFRCRRLR 180 βWWPWKLKE AEDVEREAQE AQAGKKKRKQ RRRKGRPEDL EFTDMGGNVY ILTGKVEAEF 240
ELLTVEEAEK RPVGKGRKQP EPLEKPSRPK TSFNWFVNPL KTFVFFIWRR YWRTLVLLLL 300 VLLTVFLLLV FYTIPGQISQ VIFRPLHK
A79 DNA SEQUENCE Gene name: Homo sapiens mRNA; cDNA DKFZp434K0322 (from clone DKFZp434K0322) Unigene number: Hs.161031 Probeset Accession #: AL137708 Nucleic Acid Accession #: AL137708 Coding sequence : 1315-1791 (underlined sequences correspond to start and stop codons)
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I I I I I I ββCATTβATβ CTβTβTGCGC βTβCβTβTβT βTβTGTGTβT βTGTGTGTGT GTGTGTGTGT 60
GTGTGTGTGT GTCTGGAGTC ATGGCAGGGT CCCTTTCTGT CTGTCTCCTT βCTCTβCCCC 120
A6ACTGGGGG GCTGCAGAGG TGAGββTATC TGGCCTCAAC AGCTβCTTAT TCCCGATGGG 180
ATGGCCTGGG CTGGGCCCCT GAββCCAGβC TGACTTβGAC ATGGCAAGAG GGGTCCCAGG 240
CTCTTGTβGG CAAAGCAGββ βAβGCβCCAA TβTββAββAA CAβAGTCTCC TGGCTGGCTG 300
CTGCTCTCTG GAGCGGGTGG AGTCAββGAA GAGCTβAβCT GGGGAGTCAC CCTGGGCCTG 360
GββTCACCβT AGGCCCCATβ TAGCACCCTG GTTCCCCTGC CTGTAGGTGA CAGGAGCCAG 420
CCCAGCCAGG TβTβCTCCCT CCCCAGGCCC TAGGCAGGCG GGTACAGGGG CCAGCAGCTG 480
CGCCCGCCCC ACCTTCCTTC CCACCCACAT βCCGAAGGGT GGCCAGGCAG GCAGGTGGAC 540
GAGTCCAGGC AGCGGCTGAG TCAGTGTGTG TGGAATGTTC TGGCCGCTCC CAGCTGCACC 600
CTGCCCCTAC CTGCCACCAC CTCACCTTCA TCCTCAGGCG CTGCGGCCCT GAGCCCCTGC 660
CAGGAATGCA CCTTTAGCCC AGGCCTGCTC AGTGAGCTCC βCCβACAβCC AGCCCTGCTC 720
CTCCCGCCAT βACCCTβCAβ ACCCCTCTGG GCTTCCAAGT TCCTGGGGGC TGCAGTGAAC 780
ATGCTCCACC TβCATGGCTG GCAAACCATG GTGGGCCCCA GCTGTGGTGC GTGCTGGGGT 840
AGAβGCAAββ AAβTβATGββ ACCβCAGAGA TGAGACCCCC AGGβATGAGA TGGGACCCCC 900
AGGCAβββCC CAββGTCCAG GGCCCAG6AG AGAGAAβCAβ ββAβGGAGAG AGCTTCCTGG 960
TGGAGGACGC ATCCTACAGT GGGGβCAAβG GTGCTCTGAG GTCCGGTGAA GGCAGGGACT 1020
AGGCTGCCCA GGCCCTGCCT GCTTββCTβG GGCTββGββC TGCTGGGAGG TGGCTGGGAG 1080
GCTGGGCCTG GGCAGCTAAG CTGGAGCTTT ββCCAββGTC CAGAGCCTCC CTCCCTTCAG 1140
CTTCCTGCTG CACAGAACCC TCGCCCCTGG CCACCCCGTG CTGCCTCCTT GCCCTGβCAG 1200
ACCCAβCACT GGCTGCTGCT AGTCAGATGG' GGTAGCGGGC AGGGGCCGGA GβββCCACCC 1260
TCCCAβCTGA CCCAGCCTCC TGGGCCGCTT CTTCCAAACC AGCAGGGTAG AAAGATGGGG 1320
CACCCACCAG TCTCTCCCAG TGCCCCGGCC CCAGCTGβCA CCACAGCTAT ACCTGββCTT 1380
ATTCCAβACC TTGTCGCCGG GACCCCCTGT GAGTTGTGβG ATTCCCAAGA GβββTGTGββ 1440
GATAACCCAG CCAAGTG6GG GCTGCAGCTG TCCACAGATG CACTCAGCCT GGCCTCTACC 1500
CCAGGGCCCC GCTGβGCTCT CATTGCCGGC GCCCTTGCCG CGGGCβTCCT CCTCGTCTCC 1560
TGCCTCCTCT GTGCTGCCTβ CTβCTβCTGC CGCCGCCACA GGAAGAAGCC CAGGGACAAG 1620
GAGTCCGTGG GTCTGGGCAG TGCCCGCGβC ACCACCACCA CCCACCTGGT GAGGAGCGGC 1680
TCCTTGCTCA CTCAGTCCAG AGAGGGCTTG AAATCCAGGC TCCAGAGCCC AGGGCAβCβA 1740 ββCGAGTTCA GCCCCAGGGA TGGTTTAACC CCCACAGAGG CAGGGCGTTG AββACCTTCC 1800
TGGCAGGGAA AGTGGGTβAA CAGAGGTGAG AAGGAGGCCA TGCAACAGGG GCTGCCCCAT 1860
GGGCCCGAGG GAGCCACAGC GGGTTCTTGA GGAAβGCAGG ββGTACCCCA GATGCCACGT 1920
TTTGGβTβGG TTTGGCCGGT CTCACAGAGC GAAGCCGACG ATTTGTGCCT GTTGGGTGGC 1980
CTGGCCTGGA GGCGGββββT CTTGACCCAT GTCATβCAAβ ββCTβCCCGG GAGCCCAGGG 2040
CTCTGATGAG GCATGATGTC AGCACCACCT GCCCCTTGTC CCAACTCACT CCAGGTGCAA 2100
CCTGATGTGG ATGGCCTGGA GTCCAGCCCG GGGβATGCTC AGCAATGGGG GTGCCTGCAG 2160
CTCTCCCTGG AGTTCGACTT TGGAAGCCAG GAββTβAAGG GCCCCGCTGC βCAββACCAβ 2220
CGGTTCTGCG AGTTTCCGGA AAGGGTGACG GGGGAAGGGC AGACCCCATG CCCTGGGTβG 2280
TGGGGAGCTG ACAGGGCAGG GGCCCTTGGC TGAGCCCACC CCGCTGGCTC CCAGATCAββ 2340
GTGGGCCTGA GGCAGGCAGC CGACCTGAGG CCTGGGGGCA CCGTGGACCC CTATGCCCGβ 2400
GTCAGCGTCT CCACCCAGGC CGGACACAGA CATGAGACAA AAGTGCACCG AGGCACGCTC 2460
TGCCCCGTGT TTGACGAGAC CTGCTGCTTC CACGTGAGTC AGGGATGGTC βGCTGGβTGG 2520
GCCTGGACGG CTGGATGGGC CTGGβCTGGG TGGGCCTGGG CAGCTGGβTβ GβCCTβββCA 2580
GCTGGGTGGG CCTGAGCTAG GGCAGCAGGβ CCTGGCTCAC GCCGCTGCCT CAGATCCCGC 2640
AGGCββAβCT βCCAββββCC ACCCTGCAGG TGCAGCTTTT CAACTTCAAG CGCTTCTCGG 2700
GGCATGAGCC CCTGGGTGAG CTCCGTCTGC CACTGGGCAC CGTGGATCTG CAβCATβTTC 2760
TββAGCACTG GTACCTGCTG GGCCCGCCGG CTGCCACTCA GGTGAGβTβC TGGTCACCAG 2820
GCCACAGCCC AAβGCAGAβC TGGCAβββAC CCTGCCCTAT GGGCCATCGβ AAAGACAGGC 2880
CTGATGβGCA GCATTTTCGG GGGTCTGAGC CCCAACTCGG CCAGAATCAC CCTCCCGGGC 2940
TGAAGCCCCT CTTGCTGCCC ACAGCCCGAG CAGGTCGGGG AGCTβTGCTT CTCTCTCCGG 3000
TACGTGCCCA GCTCAGβCCβ βCTGACCGTG GTGGTGCTGG AGGCTCGAGG CCTGC6TCCA 3060
GGACTTGCAG AGCCCTACGT GAAGβTCCAG CTCATGCTGA ACCAGAGGAA βTGGAAGAAβ 3120
A6AAAGACAG CCACCAAAAA GGGCACGGCG GCCCCCTACT TCAATGAβGC CTTCACCTTC 3180
CTGGTGCCCT TCAGCCAGβT CCAGAATGTG GACCTββTβC TGβCTGTCTG GGACCGCAGC 3240
CTGCCGCTCC GAACTGAGCC CGTAGGCAAG GTGCACCTGG GTGCCCGGGC CTCGGGGCAG 3300 CCCCTGCAGC ACTGGGCAGA CATGCTGGCC CACGCCCGGC GGCCCATTGC CCAGCGGCAC 3360
CCCCTGCGGC CAGCCAGGGA GGTGGACCGC ATGCTGGCCC TGCAGCCCCβ CCTTCGCCTG 3420
CGCCTGCCCT TGCCCCACTC CTGAATGCAC CACATGCCTC TGTCTCCCCG CTGAGCCCAG 3480 GCACTTGCCC AGGCCGCCCT GCAGGACCAC TGCAATAAAC GCCTTCTCCT GCC
A80 Protein sequence: Gene name : Homo sapiens mRNA; cDNA DKFZp434K0322 (from clone DKFZp434K0322) Unigene number: Hs.161031
10 Probeset Accession #: AL137708 Protein Accession #: CAB70885 Signal sequence: none found Transmembrane domains : 69-85 Cellular Localization: plasma membrane
15
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MGHPPVSPSA PAPAGTTAIP GLIPDLVAGT PCELWDSQEG CβDNPAKWβL QLSTDALSLA 60 STPβPRWALI AGALAAGVLL VSCLLCAACC CCRRHRKKPR DKESVGLGSA RGTTTTHLVR 120
20 SGSLLTQSRE GLKSRLQSPG QRGEFSPRDG LTPTEAGR
A81 DNA SEQUENCE Gene name: Cadherin 3, P-cadherin (placental) Unigene number: Hs.2877 2. Probeset Accession #: X63629
Nucleic Acid Accession #: X63629 Coding sequence: 54-2543 (start and stop codons are underlined)
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30 I I I I I I
GCGGAACACC GGCCCGCCGT CGCGGCAGCT GCTTCACCCC TCTCTCTGCA GCCATGGGGC 60
TCCCTCGTGG ACCTCTCGCG TCTCTCCTCC TTCTCCAGGT TTGCTGGCTG CAβTGCGCGG 120
CCTCCGAGCC GTGCCGGGCG GTCTTCAGGG AGGCTβAAβT GACCTTGGAG GCGGGAGGCG 180
CβGAGCAGGA GCCCGGCCAG GCGCTGGGGA AAGTATTCAT GGGCTGCCCT GGGCAAGAGC 240
35 CAGCTCT6TT TAβCACTβAT AATGATGACT TCACTGTβCβ βAATGGCGAG ACAGTCCAGG 300
AAAGAAβGTC ACTGAAGGAA AGGAATCCAT TGAAGATCTT CCCATCCAAA CGTATCTTAC 360
GAAβACACAA GAβAβATTββ βTβGTTGCTC CAATATCTGT CCCTGAAAAT GGCAAGGGTC 420
CCTTCCCCCA GAβACTβAAT CAGCTCAAGT CTAATAAAGA TAGAGACACC AAGATTTTCT 480
ACAβCATCAC ββββCCβGGβ GCAGACAGCC CCCCTβAββG TGTCTTCGCT GTAGAGAAGG 540
40 AGACAGGCTβ GTTβTTβTTβ AATAAβCCAC TβGACCGGGA GGAGATTGCC AAGTATGAGC 600
TCTTTββCCA CβCTβTGTCA GAGAATGGTG CCTCAβTGGA GGACCCCATG AACATCTCCA 660
TCATCGT6AC CGACCAGAAT GACCACAAGC CCAAβTTTAC CCAGGACACC TTCCGAGGGA 720
GTβTCTTAGA GβGAGTCCTA CCAββTACTT CTGTGATGCA GGTGACAGCC ACAGATGAGβ 780
ATGATGCCAT CTACACCTAC AATGGGGTGG TTGCTTACTC CATCCATAGC CAAGAACCAA 840
45 AGGACCCACA CGACCTCATG TTCACAATTC ACCGGAGCAC AGGCACCATC AGCGTCATCT 900
CCAGTGGCCT GGACCGGGAA AAAGTCCCTG AGTACACACT GACCATCCAG GCCACAGACA 960
TGβATββGGA CGGCTCCACC ACCACGGCAG TGGCAβTAβT ββAβATCCTT GATGCCAATG 1020
ACAATGCTCC CATGTTTGAC CCCCAGAAGT ACGAβGCCCA TGTGCCTGAG AATGCAGTGG 1080
GCCATGAβGT GCAGAββCTG ACGGTCACTG ATCTββACGC CCCCAACTCA CCAGCGTGGC 1140
50 GTGCCACCTA CCTTATCATG GGCGGTGACG ACGGGGACCA TTTTACCATC ACCACCCACC 1200
CTGAGAGCAA CCAGβGCATC CTGACAACCA GGAAGGGTTT GGATTTTGAG GCCAAAAACC 1260
AGCACACCCT GTACGTTGAA GTGACCAACβ AβGCCCCTTT TGTGCTGAAG CTCCCAACCT 1320
CCACAGCCAC CATAGTGGTC CACGTGGAGG ATGTGAATGA GGCACCTGTG TTTGTCCCAC 1380
CCTCCAAAGT CGTTGAGGTC CAGGAGGGCA TCCCCACTGG GβAβCCTGTG TβTβTCTACA 1440
55 CTβCAβAAGA CCCTGACAAG GAGAATCAAA AGATCAGCTA CCGCATCCTG AGAGACCCAG 1500
CAGGGTGGCT AGCCATGGAC CCAGACAβTG GGCAGGTCAC AGCTGTGGGC ACCCTCGACC 1560
GTGAβGATGA GCAGTTTGTG AGGAACAACA TCTATGAAGT CATGβTCTTβ GCCATGGACA 1620
ATGGAAGCCC TCCCACCACT GGCACGGGAA CCCTTCTGCT AACACTGATT GATGTCAACG 1680
ACCATββCCC AβTCCCTGAG CCCCGTCAGA TCACCATCTG CAACCAAAGC CCTGTGCGCC 1740
60 ACGTGCTGAA CATCACGβAC AAGGACCTβT CTCCCCACAC CTCCCCTTTC CAGGCCCAGC 1800
TCACAGATGA CTCAGACATC TACTβGACGG CAGAGGTCAA CGAGGAAGβT GACACAGTGG 1860
TCTTGTCCCT GAAGAAGTTC CTGAAGCAGG ATACATATGA CβTβCACCTT TCTCTGTCTG 1920
ACCATGGCAA CAAAGAGCAG CTGACGGTGA TCAGGβCCAC TGTGTGCGAC TGCCATGGCC 1980
ATGTCGAAAC CTGCCCTGβA CCCTGβAAAβ GAGGTTTCAT CCTCCCTGTG CTGGGGGCTG 2040
65 TCCTGGCTCT GCTβTTCCTC CTGCTGβTβC TGCTTTTGTT GGTGAGAAAG AAGCGGAAGA 2100
TCAAGGAGCC CCTCCTACTC CCAGAAGATβ ACACCCGTGA CAACGTCTTC TACTATGGCG 2160
AAGAGGGGGG TGβCβAAGAG GACCAβGACT ATGACATCAC CCAGCTCCAC CGAGGTCTGβ 2220
AGGCCAGGCC GGAGGTGGTT CTCCGCAATG ACGTβGCACC AACCATCATC CCGACACCCA 2280
TGTACCGTCC TAGGCCAGCC AACCCAGATG AAATCGGCAA CTTTATAATT GAGAACCTGA 2340
70 AGGCGGCTAA CACAGACCCC ACAGCCCCGC CCTACGACAC CCTCTTβGTG TTCGACTATG 2400
AGGGCAGCGG CTCCGACGCC GCGTCCCTGA GCTCCCTCAC CTCCTCCGCC TCCGACCAAG 2460
ACCAAGATTA CGATTATCTG AACGAGTGGG GCAGCCGCTT CAAGAAβCTG GCAGACATGT 2520
ACGGTGGCGG GGAGGACGAC TAGGCGGCCT GCCTGCAGββ CTGGGGACCA AACGTCAGGC 2580
CACAGAGCAT CTCCAAGGβG TCTCAGTTCC CCCTTCAGCT βAβGACTTCG GAGCTTGTCA 2640
75 GGAAGTGGCC GTAGCAACTT GGCGGAGACA GGCTATGAGT CTβACGTTAG AGTGGTTGCT 2700
TCCTTAGCCT TTCAGGAT6G AGGAATGTGG GCAGTTTGAC TTCAGCACTG AAAACCTCTC 2760
CACCTGGGCC AGββTTβCCT CAGAGGCCAA GTTTCCAGAA βCCTCTTACC TGCCGTAAAA 2820
TGCTCAACCC TGTGTCCTGβ βCCTβββCCT βCTβTβACTβ ACCTACAGTG GACTTTCTCT 2880
CTGGAATGGA ACCTTCTTAG GCCTCCTββT GCAACTTAAT TTTTTTTTTT AATGCTATCT 2940
80 TCAAAACGTT AGAβAAAGTT CTTCAAAAGT GCAGCCCAGA βCTGCTGGGC CCACTGGCCG 3000
TCCTGCATTT CTGGTTTCCA GACCCCAATG CCTCCCATTC GGATGGATCT CTGCGTTTTT 3060
ATACTβAβTG TGCCTAGGTT GCCCCTTATT TTTTATTTTC CCTGTTGCGT TβCTATAGAT 3120 GAAGGGTGAG GACAATCGTG TATATGTACT AGAACTTTTT TATTAAAGAA A A82 Protein sequence: Gene name : Cadherin 3, P-cadherin (placental) Unigene number: Hs.2877 Probeset Accession #: X63629 Protein Accession #: CAA45177 Signal sequence: 1-24 Transmembrane domain: 659-675 (second underlined sequence)
Cellular localization: plasma membrane 0
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MGLPRGPLAS LLLLQVCWLQ CAASEPCRAV FREAEVTLEA GGAEQEPGQA LGKVFMGCPG 60 5 QEPALFSTDN DDFTVRNGET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENG 120 KGPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK 180 YELFGHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RβSVLEGVLP GTSVMQVTAT 240 DEDDAIYTYN GWAYSIHSQ EPKDPHDLMF TIHRSTGTIS VISSGLDREK VPEYTLTIQA 300 TDMDGDGSTT TAVAWEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP 360 0 AWRATYLIMG GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL 420 PTSTATIWH VEDVNEAPVF VPPSKWEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR 480 DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTG TGTLLLTLID 540 VNDHβPVPEP RQITICNQSP VRHVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD 600 TWLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL 660 5 GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YβEEβββEED QDYDITQLHR 720 GLEARPEWL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF 780 DYEGSGSDAA SLSSLTSSAS DQDQDYDYLN EWGSRFKKLA DMYGGGEDD
A83 DNA SEQUENCE 0 Gene name: putative G-protein coupled receptor
Unigene number: Hs.16085
Probeset Accession #: F07953
Nucleic Acid Accession #: NM_016334
Coding sequence: 104-1471 (underlined sequences correspond to start and stop codons) 5
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AGCACCTβGG AAAAGGCAGA CCGTGTGAGG GGGCCTβTGG CCCCAGCGTG CTGTGGCCTC 60 0 GGGGAβTGββ AAGTGβAGGC AGGAGCCTTC CTTACACTTC GCCATGAGTT TCCTGATCGA 120
CTCCAGCATC ATGATTACCT CCCAAATACT ATTTTTTGGA TTTGGGTGβC TTTTCTTCAT 180
GCGCCAATTG TTTAAAGACT ATGAGATACG TCAGTATβTT GTACAGGTGA TCTTCTCCGT 240
GACβTTTβCA TTTTCTTGCA CCATGTTTGA GCTCATCATC TTTGAAATCT TAGGAGTATT 300
GAATAGCAGC TCCCGTTATT TTCACTGGAA AATGAACCTG TGCGTAATTC TGCTGATCCT 360 5 GGTTTTCATβ GTβCCTTTTT ACATTGGCTA TTTTATTGTG AGCAATATCC GACTACTGCA 420
TAAACAACGA CTGCTTTTTT CCTGTCTCTT ATGGCTGACC TTTATGTATT TCTTCTGGAA 480
ACTAGβAGAT CCCTTTCCCA TTCTCAGCCC AAAACATGGG ATCTTATCCA TAGAACAGCT 540
CATCAGCCGG GTTGGTGTGA TTGGAGTGAC TCTCATGGCT CTTCTTTCTG GATTTGGTGC 600
TGTCAACTGC CCATACACTT ACATGTCTTA CTTCCTCAGG AATβTGACTG ACACAGATAT 660 0 TCTAGCCCTG GAACGGCGAC TGCTGCAAAC CATGGATATG ATCATAAGCA AAAAGAAAAG 720
GATGGCAATG GCACGGAGAA CAATGTTCCA GAAGGGGGAA GTβCATAACA AACCATCAGβ 780
TTTCTGGGGA ATGATAAAAA GTGTTACCAC TTCAGCATCA GGAAGTGAAA ATCTTACTCT 840
TATTCAACAβ GAAGTGGATG CTTTGGAAGA ATTAAGCAGβ CAGCTTTTTC TGGAAACAGC 900
TGATCTATAT GCTACCAAGG AGAGAATAGA ATACTCCAAA ACCTTCAAGG ββAAATATTT 960 5 TAATTTTCTT GGTTACTTTT TCTCTATTTA CTGTGTTTGG AAAATTTTCA TGGCTACCAT 1020
CAATATTGTT TTTGATCGAG TTGββAAAAC GGATCCTGTC ACAAGAGGCA TTGAGATCAC 1080
TGTGAATTAT CTGββAATCC AATTTGATGT GAAGTTTTGG TCCCAACACA TTTCCTTCAT 1140
TCTTGTTβGA ATAATCATCG TCACATCCAT CAGAGGATTG CTGATCACTC TTACCAAGTT 1200
CTTTTATGCC ATCTCTAGCA GTAAGTCCTC CAATGTCATT GTCCTGCTAT TAGCACAGAT 1260 0 AATGGGCATG TACTTTGTCT CCTCTGTGCT GCTGATCCGA ATGAGTATGC CTTTAGAATA 1320
CCGCACCATA ATCACTGAAβ TCCTTGGAGA ACTGCAGTTC AACTTCTATC ACCGTTGβTT 1380
TGATGTβATC TTCCTGGTCA GCGCTCTCTC TAβCATACTC TTCCTCTATT TGGCTCACAA 1440
ACAGGCACCA GAGAAGCAAA TGβCACCTTG AACTTAAβCC TACTACAGAC TGTTAGAGGC 1500
CAGTGGTTTC AAAATTTAGA TATAAβAGGG GGGAAAAATG GAACCAGGβC CTGACATTTT 1560 5 ATAAACAAAC AAAATGCTAT GGTAGCATTT TTCACCTTCA TAβCATACTC CTTCCCCCTC 1620
AGGTβATACT ATGACCATGA GTAGCATCAG CCAGAACATG AGAGββAGAA CTAACTCAAG 1680
ACAATACTCA GCAGAGAGCA TCCCGTGTGG ATATGAGGCT GGTGTAGAGG CGGAGAGGAG 1740
CCAAGAAACT AAAββTGAAA AATACACTGG AACTCTGGGG CAAGACATGT CTATGGTAGC 1800
TGAGCCAAAC ACGTAGGATT TCCGTTTTAA GGTTCACATG GAAAAGGTTA TAGCTTTGCC 1860
70 TTGAGATTGA CTCATTAAAA TCAGAGACTG T
A84 Protein sequence Gene name: putative G-protein coupled receptor J Unigene number: Hs.16085
Protein Accession #: NP_057418.1 Signal sequence: none found Transmembrane domains: 5-27, 42-64, 76-98, 110-132, 144-166, 289-311, 342-364, 380-402, 424-446
OU Cellular Localization: plasma membrane l II : 31 41 51 MSFLIDSSIM ITSQILFFGF GWLFFMRQLF KDYEIRQYW QVIFSVTFAF SCTMFELIIF 60
EILβVLNSSS RYFHWKMNLC VILLILVFMV PFYIGYFIVS NIRLLHKQRL LFSCLLWLTF 120
MYFFWKLβDP FPILSPKHGI LSIEQLISRV GVIGVTLMAL LSGFGAVNCP YTYMSYFLRN 180
VTDTDILALE RRLLQTMDMI ISKKKRMAMA RRTMFQKGEV HNKPSGFWGM IKSVTTSASG 240
SENLTLIQQE VDALEELSRQ LFLETADLYA TKERIEYSKT FKGKYFNFLG YFFSIYCVWK 300
IFMATINIVF DRVGKTDPVT RGIEITVNYL GIQFDVKFWS QHISFILVGI IIVTSIRGLL 360
ITLTKFFYAI SSSKSSNVIV LLLAQIMβMY FVSSVLLIRM SMPLEYRTII TEVLGELQFN 420
FYHRWFDVIF LVSALSSILF LYLAHKQAPE KQMAP
A85 DNA SEQUENCE:
Gene name: TTK protein kinase Unigene number: Hs.169840 Probeset Accession ft: M86699 Nucleic Acid Accession tt: NM_003318 Coding sequence : 1026-3551 (underlined sequences correspond to start and stop codons)
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GβAATTCCTT TTTTTTTTTT TTTGA6ATGG AGTTTCACTC TTGTTGGCCA GGCTGGAGTG 60
CAATGGCACA ATCTCAβCTT ACTβCAACCT CCβCCTCCCβ GGTTCAAGCG ATTCTCCTGC 120
CTCAGCCTCT CAAGTAGCTβ CGATTACAGG CATGTGCCAC CACCCCTGGC TAACTAATTT 180
CTTTTCTATT TAGTAGAGAT GGGGTTTCAC CATGTTGGTC AGGCTGβTCT TGAACTCCTG 240
ACCTCAGGTG ATCCACTTGC CTTGGCCTCC CAAAGTGCTA GGATTACAGC CGTGAAACTG 300
TGCCTGGCTG ATTCTTTTTT TGTTGTTGGA TTTTTGAAAC AGGGTCTCCC TTGβTCGCCC 360
AGGCTGGAGT GCAGTGGTGC βATCTTGGCT CACTATAACC TCCACCTCCT GGTTTCAAGT 420
GATCCTCCCA CTTTAβCCTC CTGAGTAGCT βTGATTACAG GCGTGCACCA CCACACCCGG 480
CTAATTTTTG TATTTTTATT AGAGACAGGG TTTCACCATG TTGGCCAGGC TGTTCTCAAA 540
CTCCTβGACT CAAGGGATCC GCCTGCCTCC ACTTCCCAAA βTCCCGAGAT TACAGGTGTG 600
AGTCACCATβ CCT6ACCTTA TAATTCTTAA βTCATTTTTT CTGGTCCATT TCTTCCTTAC 660 ββTCCTCACA ACAAATCTβC ATTAβGCGGT ACAATAATCC TTAACTTCAT GATTCACAAA 720
AGβAAβATβA AβTβATTCAT GATTTAGAAA GGGGAAGTAG TAAGCCCACT GCACACTCCT 780
GGATβATGAT CCTAAATCCA GATACAGTAA AAATGGGGTA TGGGAAββTA GAATACAAAA 840
TTTGGTTTAA ATTAATTATC TAAATATCTA AAAACATTTT TGGATACATT GTTβATβTGA 900
ATGTAAGACT GTACAGACTT CCTAGAAAAC AGTTTGGGTT CCATCTTTTC ATTTCCCCAG 960
TGCAGTTTTC TGTAGAAATG GAATCCGAGG ATTTAAGTGG CAGAβAATTG ACAATTGATT 1020
CCATAATGAA CAAAGTGAGA GACATTAAAA ATAAGTTTAA AAATGAAβAC CTTACTβATG 1080
AACTAAGCTT GAATAAAATT TCTGCTGATA CTACAGATAA CTCGGGAACT GTTAACCAAA 1140
TTATGATGAT GGCAAACAAC CCAGAGβACT ββTTGAGTTT GTTGCTCAAA CTAGAGAAAA 1200
ACAGTβTTCC GCTAAGTGAT βCTCTTTTAA ATAAATTGAT TGGTCGTTAC AGTCAAGCAA 1260
TTGAAβCβCT TCCCCCAβAT AAATATββCC AAAATβAβAβ TTTTGCTAGA ATTCAAGTGA 1320
GATTTGCTGA ATTAAAAGCT ATTCAAGAβC CAGATGATGC ACGTGACTAC TTTCAAATGG 1380
CCAGAGCAAA CTGCAAGAAA TTTGCTTTTG TTCATATATC TTTTGCACAA TTTGAACTGT 1440
CACAAGGTAA TGTCAAAAAA AGTAAACAAC TTCTTCAAAA AGCTGTAGAA CGTGGAGCAβ 1500
TACCACTAGA AATGCTGGAA ATTGCCCTGC GGAATTTAAA CCTCCAAAAA AAGCAβCTGC 1560
TTTCAGAGGA GGAAAAGAAG AATTTATCAG CATCTACGGT ATTAACTGCC CAAGAATCAT 1620
TTTCCGGTTC ACTTGGGCAT TTACAGAATA GGAACAACAG TTGTβATTCC AGAββACAβA 1680
CTACTAAAGC CAGβTTTTTA TATGGAGAGA ACATGCCACC ACAAGATGCA GAAATAGGTT 1740
ACCGGAATTC ATTGAβACAA ACTAACAAAA CTAAACAGTC ATGCCCATTT GGAAGAGTCC 1800
CAGTTAACCT TCTAAATAGC CCAGATTGTG ATGTGAAGAC AGATGATTCA GTTGTACCTT 1860
GTTTTATβAA AAβACAAACC TCTAGATCAG AATGCCGAGA TTTGGTTGTG CCTGGATCTA 1920
AACCAAGTβG AAATGATTCC TGTGAATTAA GAAATTTAAA GTCTGTTCAA AATAGTCATT 1980
TCAAGGAACC TCTGGTGTCA GATGAAAAGA GTTCTGAACT TATTATTACT GATTCAATAA 2040
CCCTGAAGAA TAAAACββAA TCAAβTCTTC TAβCTAAATT AβAAβAAACT AAAGAGTATC 2100
AAGAACCAGA GGTTCCAGAG AGTAACCAGA AACAGTβGCA AGCTAAGAGA AAGTCAGAGT 2160
GTATTAACCA GAATCCTGCT GCATCTTCAA ATCACTGβCA GATTCCGGAG TTAGCCCGAA 2220
AAGTTAATAC AGAGCAGAAA CATACCACTT TTGAGCAACC TGTCTTTTCA GTTTCAAAAC 2280
AGTCACCACC AATATCAACA TCTAAATGβT TTGACCCAAA ATCTATTTGT AAGACACCAA 2340
GCAGCAATAC CTTββATβAT TACATGAGCT GTTTTAβAAC TCCAβTTGTA AAGAATGACT 2400
TTCCACCTGC TTGTCAGTTG TCAACACCTT ATGGCCAACC TGCCTGTTTC CAGCAGCAAC 2460
AGCATCAAAT ACTTGCCACT CCACTTCAAA ATTTACAGβT TTTAGCATCT TCTTCAGCAA 2520
ATGAATGCAT TTCGβTTAAA βGAAGAATTT ATTCCATATT AAAGCAGATA GGAAGTGGAG 2580
GTTCAAGCAA GGTATTTCAG GTGTTAAATG AAAAGAAACA GATATATGCT ATAAAATATG 2640
TGAACTTAGA AGAAGCAGAT AACCAAACTC TTGATAGTTA CCGGAACGAA ATAGCTTATT 2700
TGAATAAACT ACAACAACAC AGTGATAAGA TCATCCGACT TTATGATTAT βAAATCACββ 2760
ACCAGTACAT CTACATGGTA ATGGAGTGTG GAAATATTGA TCTTAATAGT TGβCTTAAAA 2820
AβAAAAAATC CATTGATCCA TGGGAACGCA AGAGTTACTG GAAAAATATG TTAβAGGCAβ 2880
TTCACACAAT CCATCAACAT GGCATTGTTC ACAGTGATCT TAAACCAGCT AACTTTCTGA 2940
TAβTTβATGG AATGCTAAAG CTAATTGATT TTGGGATTGC AAACCAAATG CAACCAGATA 3000
CAACAAGTGT TGTTAAAGAT TCTCAGGTTG GCACAGTTAA TTATATGCCA CCAGAAβCAA 3060
TCAAAGATAT GTCTTCCTCC AGAGAGAATG GGAAATCTAA GTCAAAGATA AβCCCCAAAA 3120
GTGATGTTTG GTCCTTAGGA TGTATTTTGT ACTATATβAC TTACGGGAAA ACACCATTTC 3180
AGCAGATAAT TAATCAGATT TCTAAATTAC ATGCCATAAT TGATCCTAAT CATGAAATTG 3240
AATTTCCCGA TATTCCAGAβ AAAGATCTTC AAGATGTGTT AAAGTGTTGT TTAAAAAGGG 3300
ACCCAAAACA GAGGATATCC ATTCCTGAβC TCCTGGCTCA TCCATATGTT CAAATTCAAA 3360
CTCATCCAGT TAACCAAATG GCCAAGGGAA CCACTGAAGA AATGAAATAT GTTCTGGβCC 3420
AACTTGTTGG TCTGAATTCT CCTAACTCCA TTTTGAAAGC TGCTAAAACT TTATATGAAC 3480
ACTATAGTGG TGGTGAAAGT CATAATTCTT CATCCTCCAA GACTTTTGAA AAAAAAAGGG 3540
GAAAAAAATG ATTTβCAβTT ATTCβTAATG TCAGATAGGA βGTATAAAAT ATATTGGACT 3600
GTTATACTCT TGAATCCCTG TGGAAATCTA CATTTGAAGA CAACATCACT CTGAAGTGTT 3660
ATCAGCAAAA AAAATTCAGT GAGATTATCT TTAAAAGAAA ACTGTAAAAA TAGCAACCAC 3720
TTATGβCACT GTATATATTG TAGACTTGTT TTCTCTGTTT TATGCTCTTG TGTAATCTAC 3780
TTGACATCAT TTTACTCTTG GAATAGTGGG TGGATAβCAA GTATATTCTA AAAAACTTTG 3840 TAAATAAAβT TTTβTβGCTA AAATGA
A86 Protein sequence: Gene name: TTK protein kinase Unigene number: Hs.169840 Probeset Accession #: M86699 Protein Accession #: NP_003309 Signal sequence : none found Transmembrane domains : none found Protein Kinase Domain: 510-775 Cellular Localization: cytoplasmic and nuclear
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MNKVRDIKNK FKNEDLTDEL SLNKISADTT DNSGTVNQIM MMANNPEDWL SLLLKLEKNS 60 VPLSDALLNK LIGRYSQAIE ALPPDKYGQN ESFARIQVRF AELKAIQEPD DARDYFQMAR 120 ANCKKFAFVH ISFAQFELSQ βNVKKSKQLL QKAVERGAVP LEMLEIALRN LNLQKKQLLS 180 EEEKKNLSAS TVLTAQESFS GSLGHLQNRN NSCDSRGQTT KARFLYβENM PPQDAEIGYR 240 NSLRQTNKTK QSCPFGRVPV NLLNSPDCDV KTDDSWPCF MKRQTSRSEC RDLWPGSKP 300 SGNDSCELRN LKSVQNSHFK EPLVSDEKSS ELIITDSITL KNKTESSLLA KLEETKEYQE 360 PEVPESNQKQ WQAKRKSECI NQNPAASSNH WQIPELARKV NTEQKHTTFE QPVFSVSKQS 420 PPISTSKWFD PKSICKTPSS NTLDDYMSCF RTPWKNDFP PACQLSTPYβ QPACFQQQQH 480 QILATPLQNL QVLASSSANE CISVKGRIYS ILKQIGSGGS SKVFQVLNEK KQIYAIKYVN 540 LEEADNQTLD SYRNEIAYLN KLQQHSDKII RLYDYEITDQ YIYMVMECGN IDLNSWLKKK 600 KSIDPWERKS YWKNMLEAVH TIHQHGIVHS DLKPANFLIV DGMLKLIDFG IANQMQPDTT 660 SWKDSQVGT VNYMPPEAIK DMSSSRENGK SKSKISPKSD VWSLβCILYY MTYGKTPFQQ 720 IINQISKLHA IIDPNHEIEF PDIPEKDLQD VLKCCLKRDP KQRISIPELL AHPYVQIQTH 780 PVNQMAKGTT EEMKYVLGQL VGLNSPNSIL KAAKTLYEHY SGGESHNSSS SKTFEKKRGK 840 K
A87 DNA SEQUENCE Gene name: bone morphogenetic protein 7 (osteogenic protein 1) (BMP7) Unigene number: Hs.170195 Probeset Accession # : BE616633 Nucleic Acid Accession #: NM_001719 Coding sequence: 12233--1418 (underlined sequences correspond to start and stop codons)
41
GGGCGCAGCβ GGGCCCGTCT GCAGCAAGTG ACCGACββCC GGGACGGCCG CCTGCCCCCT ' 60
CTGCCACCTG GGGCGGTGCG GGCCCGGAGC CCGGAβCCCβ GGTAGCGCGT AGAGCCGGCβ 120
CGATβCACGT GCGCTCACTG CGAGCTGCββ CβCCβCACAG CTTCGTGGCG CTCTGGGCAC 180
CCCTβTTCCT GCTGCGCTCC GCCCTGGCCβ ACTTCAGCCT GGACAACGAG GTGCACTCGA 240
GCTTCATCCA CCGβCGCCTC C6CA6CCAGG AβCβGCGGGA GATGCAGCGC GAGATCCTCT 300
CCATTTTGββ CTTGCCCCAC CGCCCGCβCC CβCACCTCCA GGGCAAGCAC AACTCGGCAC 360
CCATGTTCAT GCTGGACCTG TACAACβCCA TGGCGGTGGA GGAGGGCGGC GββCCCGGCG 420
GCCAGGGCTT CTCCTACCCC TACAAGGCCG TCTTCAGTAC CCAGGGCCCC CCTCTGGCCA 480
GCCTGCAAGA TAGCCATTTC CTCACCGACG CCGACATGGT CATGAβCTTC GTCAACCTCG 540
TGGAACATGA CAAGGAATTC TTCCACCCAC GCTACCACCA TCβAβAβTTC CGGTTTGATC 600
TTTCCAAGAT CCCAGAAGGG GAAGCTGTCA CGGCAGCCβA ATTCCGGATC TACAAGGACT 660
ACATCCGGGA ACGCTTCGAC AATGAGACGT TCCGGATCAG CGTTTATCAG GTβCTCCAGG 720
AGCACTTGGG CAGGGAATCG GATCTCTTCC TGCTCGACAG CCβTACCCTC TGGGCCTCGG 780
AGGAGGGCTβ GCTGGTGTTT GACATCACAG CCACCAGCAA CCACTGGGTG GTCAATCCGC 840
GGCACAACCT GGGCCTGCAG CTCTCβGTGG AGACGCTGGA TGGGCAGAGC ATCAACCCCA 900
AGTTGGCGGG CCTGATTCGβ CGGCACGGGC CCCAGAACAA GCAGCCCTTC ATGβTβGCTT 960
TCTTCAAGGC CACβGAGβTC CACTTCCGCA GCATCCGGTC CACGGGGAβC AAACAβCβCA 1020
GCCAGAACCG CTCCAAGACG CCCAAGAACC AGGAAGCCCT GCGGATGGCC AACGTGGCAG 1080
AGAACAGCAG CAGCGACCAG AGGCAGGCCT GTAAβAAGCA CGAGCTGTAT GTCAGCTTCC 1140
GAGACCTGββ CTGβCAGβAC TGβATCATCβ CGCCTGAAββ CTACGCCGCC TACTACTGTG 1200
AGGGGGAGTG TGCCTTCCCT CTβAACTCCT ACATGAACGC CACCAACCAC GCCATCβTβC 1260
AGACGCTGGT CCACTTCATC AACCCGGAAA CGGTGCCCAA GCCCTGCTGT GCGCCCACGC 1320
AGCTCAATGC CATCTCCGTC CTCTACTTCG ATGACAGCTC CAACGTCATC CTGAAGAAAT 1380
ACAGAAACAT GGTGGTCCGG GCCTGTGGCT GCCACTAGCT CCTCCβAβAA TTCAGACCCT 1440
TTGGGGCCAA GTTTTTCTGG ATCCTCCATT GCTCGCCTTG GCCAGGAACC AGCAGACCAA 1500
CTGCCTTTTG TGAGACCTTC CCCTCCCTAT CCCCAACTTT AAAGβTGTGA GAGTATTAGG 1560
AAACATGAGC AGCATATGGC TTTTGATCAG TTTTTCAGTG GCAGCATCCA ATGAACAAGA 1620
TCCTACAAGC TGTGCAGGCA AAACCTAGCA GGAAAAAAAA ACAACGCATA AAGAAAAATG 1680
GCCGGGCCAG GTCATTGGCT GGGAAGTCTC AGCCATGCAC GGACTCGTTT CCAGAGGTAA 1740
TTATβAGCGC CTACCAGCCA GGCCACCCAG CCGTGGGAGG AAGGGGGCβT GGCAAGGGGT 1800
GGGCACATTG GTGTCTGTGC GAAAGGAAAA TTGACCCGGA AGTTCCTGTA ATAAATGTCA 1860
CAATAAAACG AATGAATG
A88 Protein sequence:
Gene name: bone morphogenetic protein 7 (osteogenic protein 1) (B
Unigene number: Hs .170195 Probeset Accession #: BE616633 Protein Accession # : NP_001710.1 Signal sequence : 1-30 Pfam domains : TGFb_propeptide [37-281] Transmembrane domains : none found Cellular Localization: secreted MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS 60
ILβLPHRPRP HLQGKHNSAP MFMLDLYNAM AVEEGGGPGG QGFSYPYKAV FSTQGPPLAS 120
LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEβEAVT AAEFRIYKDY 180
IRERFDNETF RISVYQVLQE HLGRESDLFL LDSRTLWASE EβWLVFDITA TSNHWWNPR 240
HNLGLQLSVE TLDGQSINPK LAβLIβRHβP QNKQPFMVAF FKATEVHFRS IRSTGSKQRS 300
QNRSKTPKNQ EALRMANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEGYAAYYCE 360
GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSSNVILKKY 420
RNMWRACGC H
A89 DNA SEQUENCE:
Gene name : Homo sapiens mRNA; cDNA DKFZp56401763 (from clone DKFZp56401763) Unigene number: HS.27373 Probeset Accession #: F13036 Nucleic Acid Accession #: AC012478 Coding sequence: 1-1896 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I
ATGCGCGCCβ TβccβCTβcc CGCCCCGCTC CTGCCGCTGC TGCTGCTCGC GCTCCTGGCC 60 βCTCCCβCCβ CCCGCGCCAβ CAGAβCCCAβ TCCGTCTCCG CGCCGTβGCC CGAACCCGAG 120 CCCβAβTCβC ββCCACCβCC CGGCCCGβGG CCCGGGAACA CCACCCGGTT TGGGTCTGGβ 180 CCGGCGGGCG GCAGCGGCAG CTCCAGCTCC AACAGCAGTβ GCGACGCCTT GGTGACCCβC 240 ATTTCCATCC TCCTCCGCGA CCTACCCACC CTCAAGGCAβ CCGTGATCGT ββCGTTCGCC 300 TTTACCACCC TCCTCATCGC CTGCCTGCTG CTGCGCGTCT TCAGGTCGGβ AAAGAGGTTA 360 AAGAAGACAC GCAAGTATGA TATCATCACC ACTCCAGCAG AGCGAGTβGA AATGGCGCCA 420 CTAAATGAAG AGGATGATGA AGATGAGGAC TCCACAGTAT TCGACATCAA ATACAGAGTG 480 TCCTTGCCGG CTGCACTGAβ AC6TCAGCTG CCAGGGTGCC AGACGCTACT GACAGTTCCT 540 GTGCCCCCAC CCTTCATCCT CβACATTGAC CTTCCAGCAA GATGCAGTGG AAGGCCTGAT 600 GGTGGAATCA βACCTGGTAA AACCTGTTTC CCAGCCTGGT βGCATCCTGT GGAAAGTTGG 660 TCAGCTGCAA CCTGGβGTGT GAAGGACTGG ACCTGGAAGC CCTCTTGCGT CGGAGGTGTT 720 GAAACCAAAA CGAACGTTAT GTATAAAACC CCAGCTCCAT CGTβCβTGTC AGGCATCTGC 780 TCAGACTGTC ACTGGCAAGC TCGTTTCCAC GTCACCACAA TGGAGTTGCT TCTGCCACCC 840 TTTGGGCATC CCTTTAAAGT GCCCCCTACT TCTACTCCCC ATGGTTTTCG ACAACTGCAβ 900 CTGAATCTCA TGGAAAAGCT GGATTCCTCT GCCTTACβCA GAAACACCCG ββCTCCATCT 960 GCCAGGTGCT TGCCACTGGT CCTGGCAGAA ATGGCGGCTβ CTGAAAGTGA CCTTCCAAAT 1020 CCTTGβTGGC ACTTCAGCβC CACAGGCTCT CCAATAAAAA CCCTTTACAC ACAAACCATG 1080 AGTACCTTGG CCTTββATβT TTTCTGTββT GCCGGCCAGC GGGGCACCTT TTGTGAAGAC 1140 ACAβCAβTGA CTAAGGTTCT CCAβββTAGC TCTTTCTCCA AACAGCTβCβ CTGGAAGCCA 1200 GCCCTAGAGA GTβββTTTCC CCATCATCTC AGGCTTCTCA GAGAβTβTCC TCCGCTGAGC 1260 ACCCATCCTG TCAGGTTGGC TCβTTCAβAT GCCCGGGGAC AAGCCAGCCT GACGGGGAGG 1320 AGGGTGTTTC GGCGTCCβCG βCAβTCTCTβ CATGGCGGAG GβTCAGCGGG TACCGCAACT 1380 TGCCTTTTGG TTTTGAAβAT TCTβTTGAGG CGCCATCCTC ACCTTβACCT CTTCTACAAA 1440 ATCTGTCTCC CCTGCTGTGC CGTGGAACAC CTACGGGAAG CCAAβAGAAG CTCAGTGACT 1500 GTCCTTGCGT CATTTGAGCA GAGCCCACAA AAGGCAGCTβ CTGCCCACGG GGAGCCTGTC 1560 AAACGAGGGC CCAGTGGGCA ATTGACCAGA CACACATβCC CTGGCTGGGG GATCACACAT 1620 βCβAACCTGC AGACAATTCC AGATACCCAA GβCCAGGAAβ GCCCACGTGA GβATβTCACT 1680 CACCCTGGAG GAGACTTGGA TGGGGTβGCA AATTTCTATT TββAβGAAGA GGGTTTCCAG 1740 GATGGCAGAT GCCAGAAGAT GGTCCTGATG TCTGAGGAAG GGCCACCTAG TTTGACAβGA 1800 TGTβAGAGGC TCACAGGTTC CCATCACTTC TCCAGCCATT CCAAGTCTTG GTCCTTCCTT 1860 TCCCCCCGAC AGCCCCTGTT TCTGTCCAGG CCCTGA
A90 Protein sequence: Gene name: Homo sapiens mRNA; cDNA DKFZp56401763 (from clone DKFZp56401763) Unigene number: Hs.27373 Probeset Accession ft: F13036 Protein Accession #: FGENESH predicted Signal sequence : 1-27 Transmembrane domains: 94-115, 448-469 Cellular Localization: not determined
60
120
180
Figure imgf000874_0001
240
ETKTNVMYKT PAPSCVSGIC SDCHWQARFH VTTMELLLPP FGHPFKVPPT STPHGFRQLQ 300
LNLMEKLDSS ALRRNTRAPS ARCLPLVLAE MAAAESDLPN PWWHFSATGS PIKTLYTQTM 360
STLGLDVFCG AGQRGTFCED RAVTKVLQGS SFSKQLRWKP ALESGFPHHL RLLRECPPLS 420
THPVRLARSD ARGQASLTGR RVFRRPRQSL HGGGSAGTAT CLLVLKILLR RHPHLDLFYK 480
ICLPCCAVEH LREAKRSSVT VLASFEQSPQ KAAAAHGEPV KRGPSGQLTR HTCPGWGITH 540
ANLQTIPDTQ GQEGPREDVT HPGGDLDGVA NFYLEEEβFQ DGRCQKMVLM SEEGPPSLTG 600
CERLTGSHHF SSHSKSWSFL SPRQPLFLSR P
EWING
A91 DNA SEQUENCE
Gene name: G protein-coupled receptor 64 Unigene number: Hs.184942 Probeset Accession ft: AA435577 Nucleic Acid Accession it: NM_005756 Coding sequence: 73-3117 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I 1 I 1 I I
AGCCAGCCCG AGGACGCGAβ GGGCAGGTGT GCACAGAGGT TCTCCACTTT GTTTTCTGAA 60
CTCGCGGTCA GGATGGTTTT CTCTGTCAGG CAGTGTGGCC ATGTTGGCAG AACTGAAGAA 120
GTTTTACTGA CGTTCAAGAT ATTCCTTGTC ATCATTTGTC TTCATGTCGT TCTGβTAACA 180
TCCCTGGAAG AAGATACTGA TAATTCCAGT TTGTCACCAC CACCTGCTAA ATTATCTGTT 240
GTCAGTTTTG CCCCCTCCTC CAATGAGβTT GAAACAACAA GCCTCAATβA TGTTACTTTA 300
AGCTTACTCC CTTCAAACGA AACAGAAAAA ACTAAAATCA CTATAGTAAA AACCTTCAAT 360
GCTTCAGGCG TCAAACCCCA GAGAAATATC TGCAATTTGT CATCTATTTG CAATGACTCA 420
GCATTTTTTA GAββTβAβAT CATGTTTCAA TATGATAAAG AAAGCACTβT TCCCCAGAAT 480
CAACATATAA CGAATGGCAC CTTAACTGGA GTCCTβTCTC TAAGTGAATT AAAACGCTCA 540
GAGCTCAACA AAACCCTGCA AACCCTAAGT GAGACTTACT TTATAATGTβ TGCTACAGCA 600
GAGGCCCAAA GCACATTAAA TTGTACATTC ACAATAAAAC TGAATAATAC AATGAATGCA 660
TGTGCTGCAA TAGCCβCTTT GGAAAGAGTA AAGATTCGAC CAATGGAACA CTGCTGCTGT 720
TCTGTCAGβA TACCCTGCCC TTCCTCCCCA GAAGAGTTGG GAAAGCTTCA GTGTGACCTG 780
CAGGATCCCA TTGTCTGTCT TGCTGACCAT CCACGTGGCC CACCATTTTC TTCCAGCCAA 840
TCCATCCCAβ TGGTGCCTCG GβCCACTGTG CTTTCCCAGG TCCCCAAAβC TACCTCTTTT 900 βCTβAβCCTC CAGATTATTC ACCTGTGACC CACAATGTTC CCTCTCCAAT AGβββAβATT 960
CAACCCCTTT CACCCCAβCC TTCAGCTCCC ATAGCTTCCA GCCCTGCCAT TGACATGCCC 1020
CCACAGTCTG AAACGATCTC TTCCCCTATG CCCCAAACCC ATβTCTCCGG CACCCCACCT 1080
CCTGTGAAAG CCTCATTTTC CTCTCCCACC GTGTCTGCCC CTGCGAATGT CAACACTACC 1140
AGCGCACCTC CTGTCCAGAC AGACATCGTC AACACCAGCA GTATTTCTGA TCTTGAGAAC 1200
CAAGTGTTβC AGATGGAGAA GβCTCTGTCC TTGGGCAGCC TGGAGCCTAA CCTCGCAGGA 1260
GAAATGATCA ACCAAGTCAG CAGACTCCTT CATTCCCCGC CTGACATGCT GGCCCCTCTG 1320
GCTCAAAGAT TGCTGAAAGT AGTGGATGAC ATTββCCTAC AGCTGAACTT TTCAAACACG 1380
ACTATAAGTC TAACCTCCCC TTCTTTGGCT CTββCTGTGA TCAGAGTGAA TGCCAGTAGT 1440
TTCAACACAA CTACCTTTGT GGCCCAAGAC CCTGCAAATC TTCAGGTTTC TCTGGAAACC 1500
CAAGCTCCTG AGAACAGTAT TGGCACAATT ACTCTTCCTT CATCGCTGAT GAATAATTTA 1560
CCAGCTCATG ACATGGAβCT AGCTTCCAGG GTTCAGTTCA ATTTTTTTGA AACACCTGCT 1620
TTGTTTCAGG ATCCTTCCCT GGAGAACCTC TCTCTβATCA GCTACGTCAT ATCATCGAβT 1680
GTTGCAAACC TGACCGTCAG GAACTTGACA AGAAACGTGA CAGTCACATT AAAGCACATC 1740
AACCCGAGCC AGGATGAGTT AACAGTGAβA TGTGTATTTT GββACTTGGβ CAGAAATGGT 1800
GGCAGAGGAG GCTGβTCAGA CAATGGCTGC TCTGTCAAAG ACAGGAGATT GAATGAAACC 1860
ATCTGTACCT GTAGCCATCT AACAAGCTTC GGCGTTCTGC TGβACCTATC TAGGACATCT 1920
GTGCTCCCTG CTCAAATGAT GGCTCTGACG TTCATTACAT ATATTGβTTG TGβGCTTTCA 1980
TCAATTTTTC TGTCAGTGAC TCTTGTAACC TACATAGCTT TTGAAAAGAT CCGGAGGGAT 2040
TACCCTTCCA AAATCCTCAT CCAGCTGTGT GCTGCTCTGC TTCTGCTGAA CCTGGTCTTC 2100
CTCCTGGACT CGTGGATTGC TCTGTATAAG ATβCAAGGCC TCTGCATCTC AGTGGCTGTA 2160
TTTCTTCATT ATTTTCTCTT GGTCTCATTC ACATGGATGβ GCCTAGAAGC ATTCCATATG 2220
TACCTGGCCC TTGTCAAAβT ATTTAATACT TACATCCβAA AATACATCCT TAAATTCTGC 2280
ATTGTCGGTT GGGGGGTACC AGCTGTGβTT GTGACCATCA TCCTGACTAT ATCCCCAGAT 2340
AACTATGGGC TTβGATCCTA TGGGAAATTC CCCAATGβTT CACCCGATGA CTTCTGCTGG 2400
ATCAACAACA ATβCAGTATT CTACATTACG GTGGTG6GAT ATTTCTGTGT GATATTTTTβ 2460
CTGAACGTCA GCATβTTCAT TGTGGTCCTG GTTCAGCTCT GTCGAATTAA AAAGAAGAAG 2520
CAACTGGGAG CCCAGCGAAA AACCAGTATT CAAGACCTCA GGAβTATCGC TGGCCTTACA 2580
TTTTTACTββ GAATAACTTG GGGCTTTGCC TTCTTTGCCT GGGβACCAGT TAACGTGACC 2640
TTCATGTATC TGTTTGCCAT CTTTAATACC TTACAAGGAT TTTTCATATT CATCTTTTAC 2700
TGTGTGGCCA AAGAAAATGT CAGGAAGCAA TGGAββCGGT ATCTTTGTTG TGβAAAGTTA 2760
CGGCTGGCTG AAAATTCTGA CTGGAGTAAA ACTGCTACTA ATGGTTTAAA GAAGCAGACT 2820
GTAAACCAAG GAGTGTCCAG CTCTTCAAAT TCCTTACAGT CAAGCAGTAA CTCCACTAAC 2880
TCCACCACAC TβCTAGTβAA TAATGATTGC TCAGTACACG CAAGCGGGAA TGGAAATGCT 2940
TCTACAGAGA GGAATGGββT CTCTTTTAGT GTTCAGAATG GAGATGTGTG CCTTCACGAT 3000
TTCACTGGAA AACAGCACAT GTTTAACGAG AAGGAAβATT CCTGCAATGG GAAAGGCCGT 3060
ATGGCTCTCA GAAGGACTTC AAAGCGGGGA AGCTTACACT TTATTGAGCA AATGTGATTC 3120
CTTTCTTCTA AAATCAAAβC ATGATGCTTG ACAGTGTGAA ATGTCCAATT TTACCTTTTA 3180
CACAATGTGA GATGTATGAA AATCAACTCA TTTTATTCTC GGCAACATCT GGAGAAGCAT 3240
AAGCTAATTA AGGGCGATGA TTATTATTAC AAGAAGAAAC CAAGACATTA CACCATGGTT 3300
TTTAGACATT TCTGATTTβG TTTCTTATCT TTCATTTTAT AAGAAGGTTG GTTTTAAACA 3360
ATACACTAAG AATGACTCCT ATAAAGAAAA CAAAAAAAGG TAGTβAACTT TCAGCTACCT 3420
TTTAAAGAGG CTAAGTTATC TTTGATAACA TCATATAAAG CAACTGTTGA CTTCAGCCTG 3480
TTGGTGAGTT TAGTTGTGCA TGCCTTTβTT GTATATAAGC TAAATTCTAG TGACCCATGT 3540
GTCAAAAATC TTACTTCTAC ATTTTTTTGT ATTTATTTTC TACTGTGTAA ATGTATTCCT 3600
TTGTAGAATC ATGGTTGTTT TGTCTCACGT GATAATTCAG AAAATCCTTβ CTCGTTCCGC 3660
AAATCCTAAA GCTCCTTTTG GAGATGATAT AGGATGTGAA ATACAGAAAC CTCAGTGAAA 3720
1 TCAAGAAATA ATGATCCCAG CCAGACTGAG AAAATGTAAβ CAGACAGTβC CACAGTTAGC 3780
TCATACAβTG CCTTTGAGCA AGTTAGGAAA AGATβCCCCC ACTGGGCAGA CACAGCCCTA 3840
TGGGTCATGG TTTGACAAAC AGAGTGAGAG ACCATATTTT AβCCCCACTC ACCCTCTTGG 3900
GTβCACGACC TGTACAGCCA AACACAGCAT CCAATATGAA TACCCATCCC CTGACCGCAT 3960
CCCCAGTAGT CAGATTATAG AATCTGCACC AAGATβTTTA GCTTTATACC TTGGCCACAG 4020
AβAGGGATGA ACTGTCATCC AGACCATGTG TCAGGAAAAT TGTGAACβTA βATGAGGTAC 4080
ATACACTGCC GCTTCTCAAA TCCCCAGAβC CTTTAGGAAC AGβAGAGTAG ACTAGGATTC 4140
CTTCTCTTAA AAAGGTACAT ATATATGGAA AAAAATCATA TTGCCGTTCT TTAAAAGGCA 4200
ACTGCATβGT ACATTGTTβA TTGTTATβAC TβGTACACTC TGGCCCAGCC AGAGCTATAA 4260
TTGTTTTTTA AATGTGTCTT βAAGAATGCA CAGTGACAAG GGGAGTAβCT ATTGGβAACA 4320
GGGAACTGTC CTACACTGCT ATTGTTGCTA CATGTATCGA GCCTTGATTG CTCCTAGTTA 4380
TATACAGG6T CTATCTTβCT TCCTACCTAC ATCTGCTTGA GCAGTGCCTC AAGTACATCC 4440
TTATTAGβAA CATTTCAAAC CCCTTTTAGT TAAGTCTTTC ACTAAGGTTC TCTTGCATAT 4500
ATTTCAAGTG AATGTTGGAT CTCAGACTAA CCATAGTAAT AATACACATT TCTβTGAGTG 4560
CTGACTTGTC TTTGCAATAT TTCTTTTCTG ATTTATTTAA TTTTCTTGTA TTTATATGTT 4620 AAAATCAAAA ATGTTAAAAT CAATGAAATA AATTTGCAGT TAAGA
A92 Protein sequence Gene name : G protein-coupled receptor 64 Unigene number: Hs.184942 Protein Accession #: NP_005747.1 Signal sequence : 1-38 GPS domain: 564-615
Transmembrane domains : 624-646, 660-682, 688-710, 733-755, 783-805, 828-850 , 858-880 Cellular Localization: plasma membrane
11 31 41 51
MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HWLVTSLEE DTDNSSLSPP PAKLSWSFA 60
PSSNEVETTS LNDVTLSLLP SNETEKTKIT IVKTFNASGV KPQRNICNLS SICNDSAFFR 120
GEIMFQYDKE STVPQNQHIT NGTLTGVLSL SELKRSELNK TLQTLSETYF IMCATAEAQS 180
TLNCTFTIKL NNTMNACAAI AALERVKIRP MEHCCCSVRI PCPSSPEELG KLQCDLQDPI 240
VCLADHPRβP PFSSSQSIPV VPRATVLSQV PKATSFAEPP DYSPVTHNVP SPIGEIQPLS 300
PQPSAPIASS PAIDMPPQSE TISSPMPQTH VSGTPPPVKA SFSSPTVSAP ANVNTTSAPP 360
VQTDIVNTSS ISDLENQVLQ MEKALSLGSL EPNLAβEMIN QVSRLLHSPP DMLAPLAQRL 420
LKWDDI6LQ LNFSNTTISL TSPSLALAVI RVNASSFNTT TFVAQDPANL QVSLETQAPE 480
NSIGTITLPS SLMNNLPAHD MELASRVQFN FFETPALFQD PSLENLSLIS YVISSSVANL 540
TVRNLTRNVT VTLKHINPSQ DELTVRCVFW DLβRNGGRGG WSDNGCSVKD RRLNETICTC 600
SHLTSFGVLL DLSRTSVLPA QMMALTFITY IGCβLSSIFL SVTLVTYIAF EKIRRDYPSK 660
ILIQLCAALL LLNLVFLLDS WIALYKMQβL CISVAVFLHY FLLVSFTWMG LEAFHMYLAL 720
VKVFNTYIRK YILKFCIVβW βVPAVWTII LTISPDNYGL GSYβKFPNβS PDDFCWINNN 780
AVFYITWGY FCVIFLLNVS MFIWLVQLC RIKKKKQLGA QRKTSIQDLR SIAGLTFLLG 840
ITWGFAFFAW GPVNVTFMYL FAIFNTLQGF FIFIFYCVAK ENVRKQWRRY LCCGKLRLAE 900
NSDWSKTATN βLKKQTVNQG VSSSSNSLQS SSNSTNSTTL LVNNDCSVHA SGNGNASTER 960
NGVSFSVQNG DVCLHDFTGK QHMFNEKEDS CNGKGRMALR RTSKRGSLHF IEQM
Fibrosis
A93 DNA SEQUENCE
Gene name: EGF-like-domain; multiple 6 Unigene number: Hs.12844 Probeset Accession #: N67551 Nucleic Acid Accession tt : NM_015507 Coding sequence: 241-1902 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I
CCGCAGAGGA GCCTCGGCCA ββCTAβCCAβ GβCβCCCCCA GCCCCTCCCC AββCCβCGAβ 60
CGCCCCTGCC GCGGTGCCTG βCCTCCCCTC CCAβACTCCA βββACAβCAC CCGGTAACTG 120
CGAGTββAGC GGAGGACCCG AGCGβCTβAβ βAβAβAββAG GCGβCβGCTT AGCTGCTACβ 180
GGGTCCGGCC GGCGCCCTCC CGAGGGGGGC TCAGβAββAβ GAAββAGGAC CCGTGCGAGA 240
ATGCCTCTGC CCTGGAGCCT TGCGCTCCCG CTGCTGCTCT CCTGGGTGGC AGGTGGTTTC 300
GGGAACGCGβ CCAGTGCAAG GCATCACGGG TTGTTAGCAT CGGCACGTCA GCCTGGGGTC 360
TGTCACTATG GAACTAAACT GGCCTGCTGC TACGGCTGGA GAAGAAACAG CAAGGGAGTC 420
TGTGAAGCTA CATβCβAACC TGβATβTAAβ TTTGGTGAGT GCGTGGGACC AAACAAATGC 480
AGATGCTTTC CAGGATACAC CβββAAAACC TGCAGTCAAG ATGTGAATGA GTGTGGAATG 540
AAACCCCGGC CATGCCAACA CAGATGTGTβ AATACACACG GAAGCTACAA GTGCTTTTGC 600
CTCAGTGGCC ACATGCTCAT βCCAβATβCT ACGTGTGTGA ACTCTAGGAC ATGTGCCATG 660
ATAAACTGTC AGTACAGCTG TβAAGACACA GAAGAAGGGC CACAGTGCCT GTGTCCATCC 720
TCAGβACTCC GCCTGGCCCC AAATGGAAGA GACTGTCTAG ATATTGATGA ATGTGCCTCT 780
GGTAAAGTCA TCTGTCCCTA CAATCGAAGA TGTGTGAACA CATTTGGAAG CTACTACTGC 840
AAATGTCACA TTGGTTTCGA ACTGCAATAT ATCAGTGβAC βATATGACTG TATAGATATA 900
AATGAATGTA CTATGGATAG CCATACGTGC AGCCACCATG CCAATTGCTT CAATACCCAA 960 βGGTCCTTCA AGTGTAAATβ CAAGCAββGA TATAAAGGCA ATGGACTTCG GTGTTCTGCT 1020
ATCCCTβAAA ATTCTGTGAA GGAAGTCCTC AGAGCACCTβ GTACCATCAA AGACAβAATC 1080
AAGAAGTTβC TTCCTCACAA AAACAGCATG AAAAAβAAββ CAAAAATTAA AAATβTTACC 1140
CCAGAACCCA CCAGGACTCC TACCCCTAAG GTGAACTTβC AGCCCTTCAA CTATGAAGAG 1200
ATAGTTTCCA GAGGCβββAA CTCTCATGGA GGTAAAAAAG GGAATGAAGA GAAAATGAAA 1260
GAGGGGCTTG AGGATGAGAA AAGAGAAGAG AAAGCCCTGA AGAATGACAT AGAGβAGCGA 1320
AGCCTGCβAG GAGATGTGTT TTTCCCTAAβ GTGAATGAAG CAGGTGAATT CGGCCTβATT 1380
CTGGTCCAAA GGAAAGCGCT AACTTCCAAA CTGGAACATA AAGATTTAAA TATCTCGGTT 1440
GACTGCAGCT TCAATCATGG βATCTβTGAC TGGAAACAGG ATAβAGAAGA TGATTTTGAC 1500
TGGAATCCTG CTGATCGAGA TAATGCTATT GβCTTCTATA TββCAβTTCC GβCCTTβGCA 1560
GGTCACAAGA AAGACATTGG CCGATTGAAA CTTCTCCTAC CTβACCTβCA ACCCCAAAGC 1620
AACTTCTGTT TGCTCTTTGA TTACCGGCTG βCCGGAGACA AAGTCGGGAA ACTTCβAGTG 1680
TTTGTGAAAA ACAGTAACAA TβCCCTβGCA TGβGAGAAβA CCACGAGTGA GGATβAAAAG 1740
TGGAAβACAG GGAAAATTCA GTTGTATCAA GβAACTGATG CTACCAAAAG CATCATTTTT 1800
GAAβCAGAAC GTGGCAAGGG CAAAACCββC βAAATCβCAβ TGGATGGCGT CTTGCTTGTT 1860
TCAβGCTTAT GTCCAGATAG CCTTTTATCT GTGGATβACT_ GAATGTTACT ATCTTTATAT 1920
TTGACTTTGT ATGTCAβTTC CCTGGTTTTT TTGATATTGC ATCATAGGAC CTCTGGCATT 1980
TTAGAATTAC TAGCTGAAAA ATTGTAATGT ACCAACAβAA ATATTATTGT AAGATβCCTT 2040
TCTTGTATAA GATATGCCAA TATTTGCTTT AAATATCATA TCACTGTATC TTCTCAGTCA 2100
TTTCTGAATC TTTCCACATT ATATTATAAA ATATββAAAT GTCAGTTTAT CTCCCCTCCT 2160
CAGTATATCT GATTTGTATA AGTAAGTTGA TGAGCTTCTC TCTACAACAT TTCTAGAAAA 2220
TAβAAAAAAA AGCACAGAGA AATGTTTAAC TGTTTGACTC TTATGATACT TCTTGGAAAC 2280
TATβACATCA AAGATAGACT TTTGCCTAAG TGGCTTAGCT βGGTCTTTCA TAGCCAAACT 2340
TGTATATTTA AATTCTTTGT AATAATAATA TCCAAATCAT CAAAAAAAAA AAAAAAAA A94 ProteinL sequence:
Cene name : EβF-like-domain; multiple 6
Unigene number: Hs.12844
Probeset Accession #: N67551
Protein Accession #: NP_056322 .2
Signal sequence: 1-21
Transmembrane domains : none found
MAM domain: 402-546
EGF domain: 80-259
Cellular Localization: secreted
1 11 21 31 41 51 I 1 1 1 | 1 1 1 | 1 | 1 MPLPWSLALP LLLSWVAGGF GNAASARHHβ LLASARQPGV CHYGTKLACC YGWRRNSKGV 60
CEATCEPGCK FGECVGPNKC RCFPGYTGKT CSQDVNECGM KPRPCQHRCV NTHGSYKCFC 120
LSGHMLMPDA TCVNSRTCAM INCQYSCEDT EEGPQCLCPS SGLRLAPNGR DCLDIDECAS 180
GKVICPYNRR CVNTFGSYYC KCHIβFELQY ISGRYDCIDI NECTMDSHTC SHHANCFNTQ 240
GSFKCKCKQG YKGNGLRCSA IPENSVKEVL RAPGTIKDRI KKLLAHKNSM KKKAKIKNVT 300
PEPTRTPTPK VNLQPFNYEE IVSRGGNSHG GKKGNEEKMK EGLEDEKREE KALKNDIEER 360
SLRGDVFFPK VNEAGEFG I LVQRKALTSK LEHKDLNISV DCSFNHGICD WKQDREDDFD 420
WNPADRDNAI GFYMAVPALA GHKKDIGRLK LLLPDLQPQS NFCLLFDYRL AGDKVGKLRV 480
FVKNSNNALA WEKTTSEDEK WKTGKIQLYQ βTDATKSIIF EAERGKGKTG EIAVDGVLLV 540
SGLCPDSLLS VDD
GLIOBLASTOMA
A9S DNA SEQUENCE Gene name: ESTs Unigene number: Hs.293616 Probeset Accession #: AW043782 Nucleic Acid Accession #: none found
Coding sequence: 38-1075 (underlined sequence corresponds to start and stop codon)
11 21 31 41 51
AGCAACGACG CCGGGCAGCG GGAβCGGCGG CCGCGCCATG TGGCTGCTGβ GGCCGCTGTG 60
CCTGCTGCTG AGCAGCGCCG CGGAGAGCCA GCTGCTCCCC βGGAACAACT TCACCAATGA 120
GTGCAACATA CCAGGCAACT TCATGTGCAG CAATGGACGG TGCATCCCβG GCGCCTGGCA 180
GTGTGACGGG CTGCCTGACT GCTTCGACAA GAGTGATGAG AAGGAGTβCC CCAAGGCTAA 240
GTCGAAATGT GGCCCAACCT TCTTCCCCTG TGCCAGCGGC ATCCATTβCA TCATTGGTCG 300
CTTCCββTGC AATGGGTTTG AββACTGTCC CGATGGCAGC GATGAAGAGA ACTGCACAGC 360
AAACCCTCTβ CTTTGCTCCA CCGCCCGCTA CCACTGCAAG AACGGCCTCT GTATTGACAA 420
GAGCTTCATC TGCGATGGAC AGAATAACTβ TCAAGACAAC AGTGATGAGG AAAGCTGTGA 480
AAGTTCTCAA GAACCCGGCA GTGGGCAGGT GTTTGTGACT TCAGAGAACC AACTTGTGTA 540
TTACCCCAGC ATCACCTATG CCATCATCGG CAβCTCCGTC ATTTTTβTGC TGβTGGTGGC 600
CCTGCTββCA CTGGTCTTGC ACCACCAGCG GAAGCGGAAC AACCTCATGA CGCTGCCCGT 660
GCACCGGCTG CAGCACCCTG TGCTGCTGTC CCGCCTGGTG GTCCTGGACC ACCCCCACCA 720
CTGCAACβTC ACCTACAACG TCAATAATGG CATCCAGTAT GTGGCCAGCC AGGCGGAGCA 780
GAATGCGTCG GAAGTAGGCT CCCCACCCTC CTACTCCGAG GCCTTGCTGG ACCAGAGGCC 840
TGCGTGGTAT GACCTTCCTC CACCGCCCTA CTCTTCTGAC ACβGAATCTC TGAACCAAGC 900
CGACCTGCCC CCCTACCGCT CCCGGTCCGG GAGTGCCAAC AGTGCCAGCT CCCAGGCAGC 960
CAGCAGCCTC CTGAGCGTGG AAGACACCAG CCACAGCCCG GGGCAGCCTG GCCCCCAGGA 1020
GGGCACTGCT GAGCCCAGGG ACTCTGAGCC CAGCCAGGGC ACTGAAGAAG TATAAβTCCC 1080
AGTTATTCCA AAGTCCATAT GGGTTAATCT GCTCTGACTT GTTGCCATTC TAACAATTTG 1140
TGCTCATGGG AAGCTCTTTA AGCACCTGTA AGGATGTCTC AAGTTACAGT TTGGGATATT 1200
AACTATCTCT GCATTCCCCT CCTCCCCCAG ACTTCAGAGA TGTTTTTCTG GCGTCTCAGT 1260
TGACATGATC TGTTGTGCGT CTTTTCTGTC AGGTCACTCT TCCCTTGGGA CCCGAGATCA 1320
CACCCTCATT TTTCACATTA TTCTGTTTCT GTTGGAGAGA CAGCATATAA AACAGTATTG 1380
AAATAGGCTG GGAGAGAGCA ATGTTTCTGT GCTATATTGβ ATGCTCAGAA GTGCAGGAGA 1440
CGCTGGACCC AATTCTCTCT GCTGGGTAβT TACCTTATAβ CATTTGGGGA TTTGGGTTAG 1500
ATGATCTAAC CAGGAGGCCA TCACTGGATG GTCACCCCCC CAAAAAAATT CCATTTGAGC 1560
ATCAAAACCT GCTTTGCACA ATCCTATTTG ATGCCCCCAG TTCAGCAGAG TCAGTGGCCA 1620
AAGAAAACTT TGGACGTGAG TAACACCCTT CAGCAβTCGC AACGTTATTT TGβTTTTGTG 1680
AAGGACTCTG AAACCATCTA CCCTGTATAA ATTCTGGCTT TAGAAATTTG CCCAAGAATG 1740
CTCATTCTGA GAGCTTTCCT CAGCAGCATA TATCATCAGC CTCATCCTAA AATAGGCAGG 1800
GAGCCCCTCC CATGAGTTTA TCCAAGTTCT CAGCTCCTAA AATGCAGGCT GCCAAGACCC 1860
TACACCTβCC CTGGCTCTAC AGCCACTTAC CTGGTTTCTG GACTGTCACC CTCCCAGCTG 1920
ACCTGCCCGT AGCCAAGGAA TGAGGACCTA ACTTGAGTTG GCCCAAAGTC TGACCTGGCT 1980
GTATGTCCCT GTGGCCCACA CCCAGCCTGT CTTGCTCATT CATGCAGCCT CAACACTGGC 2040
CTCCAAAGTT CCCTTAACAC TTGCAAAGTC CTTTTTACCT GTβCATTTGG ACTTGAGGAC 2100
ACTGGTTTCT ATCACAGGTβ AGAβCCATβT TCAATACCTC CAGCAAGCTC TCCTGGCTCC 2160
CTGCACTβTG CACGCTCCTC TTCCCAAGGT CCCAATACCA GCACCTCTAβ TTAGAGTTAG 2220
GGTCAGGGTC AGβCCTCTCC CAACATCCCA GTAGTTTCTC CTCTGAGACA CATGGGCAAG 2280
AGACAATTTG GAGTCAAGAT TTTCCATTTG GATCTATTTT AAATCTTTTA GAAATGCATT 2340
TGAAACAGTβ TGTTTGTTTT TTCCCTTCTA GTTAAGGGAC TATTTATATG TGTATAGGAA 2400
AGCTGTCTCT TTTTTTGTTT TTCCTTTAAC AAGβTCCAAA GAAAGATGCA AAAGGAGATC 2460
ACACCCTTGC CCCGCTGAGC CCCGTGATAA CAAGTCACTC CAGACTAACC TGTGTGCCAG 2520
ACATTTGTGC ATTGTTGCAC TTTGAGGTTA TTATTTATCA AGTTCTTGAA GβAAGCAGAA 2580
AGAGGGACTC CTCTCTCCCT CCGTGTATAG TCTCTATGTT TGTGCTAGTT TTTCTTTTTT 2640
TTCTCTGTGT CCAGTCAGCC ACAGGGCCCG CCTCCCTGCA GGAATAAGGG GTAAAACGTT 2700
AGGTGTTGTT TGGCAAGAAA CCACACTGAC TGATGAGGGG TAAAATGβAA CCAGGTAGAG 2760
CCACTCCGGG CAGCTGTCAC CCATTCAGAA CTTCTTTCCG CAGCTGAAGA AATGTTCAGT 2820
AACCTβTTTβ ACGCTAATTA AAACAGAGCC TGCAGGAAGT GGGGCTAAAG TββCATTCAβ 2880 TGATCCTGTT CTGTAGACTT TTCTTTCTTT TTTTAACCAA ATCCAAAGGA TGTTACACAA 2940 AAGCTAGCCA CTGGTATTTT GTTTTβTTTA AAAAAAAAAA GAAAβAAAGA AAGAAAGAAA 3000 AACGGAAAGG AACCTAGCTG CCTβTATCTT TCATTTTTAA AATAGCACTT GAGTTATTTT 3060 CTGAGTAATC CAATAAAGAA CTTTTGATGA CAGCCAGAAT GTβTTAGAAC TCTGGCTGAA 3120 CATTTCATCT CCTGTGAGTC AGAAGGGCTT TATTTCTCCC TTTGATGGGG CCCCTTCTTC 3180 TTTCTGGTGC TCTGGAAGTT GTTTAGAGβA AAGAATTCTA ATTTTAATTA ATTGCGCAGT 3240 GAGTTAATCT CACTCGCTTT TCTβCTTCCA GGCATCTTAG GAAAAACAAA TGGTTTTAGT 3300 AGATAAGGGA TGCCTACTAA TGCTTTTTTA AAACAAACAG GGACATTTTT ATTATAGATT 3360 TGATTTTTTT AATGAATGTT TTTAAAAATA TATAAATAGG ACACCAAAGC GGCAGGGTTT 3420 TTTTTGGGGG GAGGGGGTTT GTTTTCCAAC TCAAGATGGC ACATTAGTGG CCAGCAATAT 3480 TTTTTAACTC ATTCCAACCA GGAAGCTTTT TTATACATTG CCTAAATCTA CGCCAACCAG 3540 AAAATAGTCT CATCTCTTTT TTTCTCAAAT GAGATCCGTG TTTTATTTTA GCATTAAATT 3600 AGTTACACTG TGATGACTGG CCTATTACCT GACTCAGCTC CCTCTACCTT GAAATTGACA 3660 TTTTTAAAAA ATGCAACTAA GTGGTTAATA GTGTβTGACG CTCAAAGTTA ATGTAAACTG 3720 GAAAβGTTGT GTGTCGTTGC TTTTTGTGTT TTGGTTAGGC TTGGTTTTGT TTTTTAATTT 3780 TTATACTTTC TAATAAATTT GCAGTTTCAT TCTTTCTGTT TGTGCAAAWG GWMCTAMARM 3840 AAMMAAAAAC AWYWTTGGGG GGGCTTGGGC CTCGGAAAAA GTTTTTAACA CCACTTCGGG 3900 TGGGGCGGCG GGGCCCAC6T AGGTACGGCG ACCACGCGGG CCCAAACGGG ACCCCAGAAβ 3960 GAAACCCTGG CCAAGAAAAA GGTβGCGAGA ATTCTCCACA CCAGAAAAAA ACGCGCCGGG 4020 GGAAACCGCA GAGTGTTβCG TAAACCACAC CCGAAGAGAG AACTCAGAAG CACACAAGCG 4080 GβACTCAACC AGGAGGACCC AAGGGAACCC GATAGAGTAC G
A96 Protein sequence : Gene name : ESTs Unigene number: Hs .293616 Probeset Accession # : AW043782 Protein Accession # : none found Signal sequence: 1-17 Transmembrane domains : 169-191 LDLa domains: 28-66, 70-108 , 112-149 Cellular Localization: plasma membrane
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MWLLGPLCLL LSSAAESQLL PGNNFTNECN IPβNFMCSNG RCIPβAWQCD GLPDCFDKSD 60
EKECPKAKSK CGPTFFPCAS GIHCIIGRFR CNGFEDCPDG SDEENCTANP LLCSTARYHC 120
KNGLCIDKSF ICDGQNNCQD NSDEESCESS QEPGSGQVFV TSENQLVYYP SITYAIIGSS 180
VIFVLWALL ALVLHHQRKR NNLMTLPVHR LQHPVLLSRL WLDHPHHCN VTYNVNNGIQ 240
YVASQAEQNA SEVGSPPSYS EALLDQRPAW YDLPPPPYSS DTESLNQADL PPYRSRΞGSA 300 NSASSQAASS LLSVEDTSHS PGQPGPQEGT AEPRDSEPSQ GTEEV
LUNG
A97 DNA SEQUENCE
Gene name: putative GPCR, Weakly similar to dJ365012.1 Unigene number: Hs.256897 Probeset Accession #: BE001836
Nucleic Acid Accession #: BE001836 Coding sequence: 1-2955 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 1 1 | 1 | 1 | 1 | 1 | 1 ATGGCCGTCA AATCTTTTTC CTTCAACACT GGGAATGATG GGCTAGACCC AGACCCAATC 60
ATGTTAAGTA TGATAGGGAT CAGTGGCCCA GCTGGTGTGG AAGACAAGTG GGTCATACTG 120
GGTTTAGGCC CACATAGCAC TAAAGGTCTT CAACATGCAA TTAGAAGCTC AAATGTTGAC 180
GβGAATATTG TTCACTCTAA AAAAGATGTT TCTATTAGAA TTTACTTACT CTTTCATGAA 240
AACATAGATG CTTCCTCTTT CCTGATTAGT GATGGCCATC AGTTAACCCA AGTGCACTCA 300
GAGAAGTCAA ATTCTGACAC AATCCAGCAA GTAACTATAA AAACTGATGG CCCAGTCGAA 360
GAATATCAGC TGCTGCTTCA GGTGACCTAT AGAGATTCCA AGGAGAAAAG AβATTTGAGA 420
AATTTTCTβA AGCTCTTGAA GCCTCCATTA TTATGGTCAC ATGGGCTAAT TAGAATTATC 480
AGAGCAAAGG CTACCACAGA CTGCAACAGC CTGAATGGAG TCCTGCAGTG TACCTGTGAA 540
GACAGCTACA CCTGGTTTCC TCCCTCATGC CTTGATCCCC AGAACTGCTA CCTTCACACG 600
GCTGGAGCAC TCCCAAGCTG TGAATGTCAT CTCAACAACC TCAGCCAGAG TβTCAATTTC 660
TβTGAGAGAA CAAAGATTTG GββCACTTTC AAAATTAATG AAAGGTTTAC AAATGACCTT 720
TTGAATTCAT CTTCTGCTAT ATACTCCAAA TATGCAAATG GAATTGAAAT TCAACTTAAA 780
AAAGCATATG AAAGAATTCA AGGTTTTGAG TCGGTTCAGG TCACCCAATT TCGAAATGGA 840
AGCATCGTTG CTGGGTATGA AGTTGTTGGC TCCAGCAGTG CATCTGAACT GCTGTCAβCC 900
ATTGAACATG TTGCCGAGAA GGCTAAGACA GCCCTTCACA AGCTGTTTCC ATTAGAAGAC 960
GGCTCTTTCA GAβTGTTCGG AAAAGCCCAG TGTAATGACA TTGTCTTTGG ATTTGGGTCC 1020
AAGGATGATG AATATACCCT GCCCTGCAGC AGTGGCTACA GGGGAAACAT CACAGCCAAβ 1080
TGTGAGTCCT CTGGGTGGCA GGTCATCAGG GAGACTTGTG TGCTCTCTCT GCTTGAAGAA 1140
CTGAACAAGA ATTTCAGTAT GATTGTAGGC AATGCCACTG AGGCAGCTGT GTCATCCTTC 1200
GTGCAAAATC TTTCTGTCAT CATTCGGCAA AACCCATCAA CCACAGTGGG GAATCTGGCT 1260
TCβGTGGTGT CGATTCTGAG CAATATTTCA TCTCTGTCAC TGGCCAGCCA TTTCAGβGTG 1320
TCCAATTCAA CAATGGAβGA TGTCATCAGT ATAGCTβACA ATATCCTTAA TTCAGCCTCA 1380
GTAACCAACT GGACAGTCTT ACTGCGGGAA GAAAAGTATG CCAGCTCACG GTTACTAGAG 1440
ACATTAGAAA ACATCAGCAC TCTGGTGCCT CCGACAGCTC TTCCTCTGAA TTTTTCTCββ 1500
AAATTCATTG ACTGGAAAGG GATTCCAβTβ AACAAAAGCC AACTCAAAAG GGGTTACAGC 1560
TATCAGATTA AAATGTGTCC CCAAAATACA TCTATTCCCA TCAGAGGCCG TGTGTTAATT 1620
GGGTCAGACC AATTCCAGAG ATCCCTTCCA GAAACTATTA TCAGCATGGC CTCGTTGACT 1680
CTGGGGAACA TTCTACCCGT TTCCAAAAAT GGAAATGCTC AGβTCAATβG ACCTGTGATA 1740 TCCACGGTTA TTCAAAACTA TTCCATAAAT βAAGTTTTCC TATTTTTTTC CAAGATAGAG 1800 TCAAACCTGA GCCAGCCTCA TTGTGTGTTT TGGGATTTCA GTCATTTβCA GTGGAACGAT 1860 GCAGGCTGCC ACCTAGTGAA TGAAACTCAA GACATCGTβA CGTGCCAATG TACTCACTTG 1920 ACCTCCTTCT CCATATTGAT GTCACCTTTT βTCCCCTCTA CAATCTTCCC CGTTGTAAAA 1980 TGGATCACCT ATGTGGGACT GGGTATCTCC ATTGGAAGTC TCATTTTATG CCTGATCATC 2040 GAGGCTTTGT TTTGβAAGCA GATTAAAAAA AGCCAAACCT CTCACACACG TCGTATTTGC 2100 ATGGTGAACA TAGCCCTGTC CCTCTTGATT GCTGATGTCT GGTTTATTGT TGGTGCCACA 2160 GTGGACACCA CGGTGAACCC TTCTGGAGTC TGCACAGYTG CTGTGTTCTT TACACACTTC 2220 TTCTACCTCT CTTTGTTCTT CTGGATGCTC ATGCTTGGCA TCCTGCTGGC TTACCGGATC 2280 ATCCTCGTGT TCCATCACAT GGCCCAGCAT TTGATGATGG CTGTTGGATT TTGCCTβGGT 2340 TATGGβTGCC CTCTCATTAT ATCTGTCATT ACCATTGCTG TCACGCAACC TAGCAATACC 2400 TACAAAAGGA AAGATGTGTG TTGGCTTAAC TGβTCCAATG GAAGCAAACC ACTCCTGGCT 2460 TTTGTTGTCC CTGCACTGGC TATTGTGGCT GTGAACTTCG TTGTGβTGCT GCTAGTTCTC 2520 ACAAAGCTCT GGAGGCCGAC TGTTGGGGAA AGACTGAGTC GGGATGACAA GGCCACCATC 2580 ATCCGCGTGG GGAAGAβCCT CCTCATTCTG ACCCCTCTGC TAGGGCTCAC CTGGGGCTTT 2640 GGAATAGGAA CAATAGTββA CAGCCAGAAT CTGGCTTGGC ATGTTATTTT TGCTTTACTC 2700 AATGCATTCC AGGGATTTTT TATCTTATGC TTTGGAATAC TCTTGGACAG TAAGCTGCGA 2760 CAACTTCTGT TCAACAAGTT GTCTGCCTTA AGTTCTTGβA AGCAAACAGA AAAGCAAAAC 2820 TCATCAGATT TATCTGCCAA ACCCAAATTC TCAAAGCCTT TCAACCCACT GCAAAACAAA 2880 GGCCATTATG CATTTTCTCA TACTGGA6AT TCCTCCGACA ACATCATGCT AACTCAGTTT 2940 GTCTCAAATG AATAA
A98 PROTEIN SEQUENCE Gene name : putative GPCR, Weakly similar to dJ365012.1 Unigene number: Hs.256897 Protein Accession #: none found Signal sequence : 1-17 Pfam domain: 7tm_2 [561-820] Transmembrane domains: 545-567 , 571-593 , 605-627, 641-663 , 677-699, 721-743 , 767-789 Cellular Localization: plasma membrane
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I I I I I
MHALLLCFSV LNGASβLSLL QSPVEEYQLL LQVTYRDSKE KRDLRNFLKL LKPPLLWSHG 60 LIRIIRAKAT TDCNSLNβVL QCTCEDSYTW FPPSCLDPQN CYLHTAGALP SCECHLNNLS 120 QSVNFCERTK IWGTFKINER FTNDLLNSSS AIYSKYANGI EIQLKKAYER IQGFESVQVT 180 QFRNGSIVAβ YEWGSSSAS ELLSAIEHVA EKAKTALHKL FPLEDGSFRV FGKAQCNDIV 240 FGFGSKDDEY TLPCSSGYRG NITAKCESSG WQVIRETCVL SLLEELNKNF SMIVGNATEA 300 AVSSFVQNLS VIIRQNPSTT VGNLASWSI LSNISSLSLA SHFRVSNSTM EDVISIADNI 360 LNSASVTNWT VLLREEKYAS SRLLETLENI STLVPPTALP LNFSRKFIDW KGIPVNKSQL 420 KRGYSYQIKM CPQNTSIPIR GRVLIGSDQF QRSLPETIIS MASLTLGNIL PVSKNGNAQV 480 NGPVISTVIQ NYSINEVFLF FSKIESNLSQ PHCVFWDFSH LQWNDAGCHL VNETQDIVTC 540 QCTHLTSFSI LMSPFVPSTI FPWKWITYV GLGISIGSLI LCLIIEALFW KQIKKSQTSH 600 TRRICMVNIA LSLLIADVWF IVGATVDTTV NPSGVCTAAV FFTHFFYLSL FFWMLMLGIL 660 LAYRIILVFH HMAQHLMMAV GFCLGYGCPL IISVITIAVT QPSNTYKRKD VCWLNWSNGS 720 KPLLAFWPA LAIVAVNFW VLLVLTKLWR PTVGERLSRD DKATIIRVGK SLLILTPLLG 780 LTWGFGIGTI VDSQNLAWHV IFALLNAFQV RTVTITYCIV K
A99 DNA SEQUENCE
Gene name: putative G-protein coupled receptor
Unigene number: Hs .16085
Probeset Accession # : F07953
Nucleic Acid Accession # : NM_016334
Coding sequence: 104-1471 (underlined sequences correspond to start and stop codons) '
1 11 21 31 41 51 1 1 ] 1 | 1 | 1 i 1 AGCACCTGGG AAAAGGCAGA CCGTβTGAGG GGGCCTGTGG CCCCAGCGTG CTGTGGCCTC 60
GGGGAGTβGG AAGTGGAGGC AGGAGCCTTC CTTACACTTC GCCATGAGTT TCCTGATCGA 120
CTCCAGCATC ATGATTACCT CCCAAATACT ATTTTTTGGA TTTGβGTGGC TTTTCTTCAT 180
GCGCCAATTG TTTAAAβACT ATGAGATACβ TCAGTATβTT GTACAGGTGA TCTTCTCCGT 240
GACGTTTGCA TTTTCTTβCA CCATβTTTGA GCTCATCATC TTTGAAATCT TAGGAGTATT 300
GAATAGCAGC TCCCGTTATT TTCACTGGAA AATGAACCTG TGCGTAATTC TβCTGATCCT 360
GGTTTTCATG GTGCCTTTTT ACATTGGCTA TTTTATTGTG AGCAATATCC GACTACTGCA 420
TAAACAACGA CTGCTTTTTT CCTGTCTCTT ATGGCTGACC TTTATGTATT TCTTCTGGAA 480
ACTAGGAGAT CCCTTTCCCA TTCTCAGCCC AAAACATGGG ATCTTATCCA TAGAACAGCT 540
CATCAGCCGG GTTGGTGTGA TTGGAGTGAC TCTCATGGCT CTTCTTTCTG GATTTGGTGC 600
TGTCAACTGC CCATACACTT ACATGTCTTA CTTCCTCAGG AATGTGACTG ACACAGATAT 660
TCTAGCCCTG GAACβGCGAC TGCT6CAAAC CATGGATATG ATCATAAGCA AAAAGAAAAG 720
GATGGCAATG GCACβGAGAA CAATGTTCCA GAAGGGGGAA GTGCATAACA AACCATCAGG 780
TTTCTGGGGA ATGATAAAAA GTGTTACCAC TTCAGCATCA GGAAGTGAAA ATCTTACTCT 840
TATTCAACAG GAAGTGGATG CTTTGGAAGA ATTAAGCAGG CAGCTTTTTC TGGAAACAGC 900
TGATCTATAT GCTACCAAGG AGAGAATAGA ATACTCCAAA ACCTTCAAGG GGAAATATTT 960
TAATTTTCTT GGTTACTTTT TCTCTATTTA CTGTGTTTβG AAAATTTTCA TGGCTACCAT 1020
CAATATTGTT TTTGATCGAG TTGGGAAAAC GβATCCTGTC ACAAGAGGCA TTGAGATCAC 1080
TGTGAATTAT CTGGGAATCC AATTTGATGT GAAGTTTTGG TCCCAACACA TTTCCTTCAT 1140
TCTTGTTGGA ATAATCATCG TCACATCCAT CAGAβGATTG CTGATCACTC TTACCAAGTT 1200
CTTTTATβCC ATCTCTAGCA βTAAβTCCTC CAATGTCATT GTCCTGCTAT TAGCACAGAT 1260
AATGGGCATG TACTTTGTCT CCTCTGTGCT GCTGATCCGA ATGAβTATGC CTTTAGAATA 1320
CCGCACCATA ATCACTGAAG TCCTTGGAGA ACTGCAGTTC AACTTCTATC ACCGTTGGTT 1380
TGATGTGATC TTCCTGGTCA GCGCTCTCTC TAGCATACTC TTCCTCTATT TββCTCACAA 1440 ACA6GCACCA GAGAAGCAAA TGGCACCTTβ AACTTAAβCC TACTACAGAC TGTTAGAGGC 1500 CAGTGGTTTC AAAATTTAGA TATAAβAGGG GGGAAAAATG GAACCAGGGC CTGACATTTT 1560 ATAAACAAAC AAAATGCTAT GβTAβCATTT TTCACCTTCA TAGCATACTC CTTCCCCCTC 1620 AGGTGATACT ATGACCATGA GTAGCATCAG CCAGAACATG AGAGββAβAA CTAACTCAAG 1680 ACAATACTCA GCAGAGAGCA TCCCGTGTGG ATATGAGGCT GGTGTAGAGG CGGAGAββAG 1740 CCAAGAAACT AAAGGTGAAA AATACACTGG AACTCTGGGG CAAGACATGT CTATββTAGC 1800 TGAβCCAAAC ACGTAGGATT TCCGTTTTAA GGTTCACATG GAAAAGGTTA TAGCTTTGCC 1860 TTGAGATTGA CTCATTAAAA TCAGAGACTG T
A100 Protein sequence Gene name: putative G-protein coupled receptor Unigene number: Hs.16085 Protein Accession ft: NP_057418.1 Signal sequence : none found Transmembrane domains: 5-27, 42-64, 76-98, 110-132, 144-166, 289-311, 342-364, 380-402, 424-446 Cellular Localization: plasma membrane
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MSFLIDSSIM ITSQILFFGF GWLFFMRQLF KDYEIRQYW QVIFSVTFAF SCTMFELIIF 60
EILGVLNSSS RYFHWKMNLC VILLILVFMV PFYIGYFIVS NIRLLHKQRL LFSCLLWLTF 120
MYFFWKLGDP FPILSPKHGI LSIEQLISRV GVIGVTLMAL LSGFGAVNCP YTYMSYFLRN 180
VTDTDILALE RRLLQTMDMI ISKKKRMAMA RRTMFQKGEV HNKPSGFWGM IKSVTTSASβ 240
SENLTLIQQE VDALEELSRQ LFLETADLYA TKERIEYSKT FKGKYFNFLG YFFSIYCVWK 300
IFMATINIVF DRVGKTDPVT RGIEITVNYL GIQFDVKFWS QHISFILVGI II TSIRβLL 360
ITLTKFFYAI SSSKSSNVIV LLLAQIMGMY FVSSVLLIRM SMPLEYRTII TEVLβELQFN 420
FYHRWFDVIF LVSALSSILF LYLAHKQAPE KQMAP
A101 DNA SEQUENCE βene name: ESTs, Weakly similar to CβHU7L collagen alpha l(III) chain precursor [H. sapiens]
Unigene number: Hs.19322
Probeset Accession #: AA088458
Nucleic Acid Accession #: AA088458
Coding sequence: 862-1995 (underlined sequences correspond to start and stop codons)
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GCCCTTGGAC ACTGACATGG ACTGAAGGAG TAGAATGGAG CACβAGGACA CTGACATGGA 60
CTβAAGAAAA AGGAGCTGGA GCAGGAGAAG GAGGTGCTGC TGCAGGGTTT GGAGATGATG 120
GCGCGGGGCC GCGACTGGTA CCAGCAGCAG CTGCAACGAG TGCAGGAGCβ CCAGCCCCGC 180
CTGGGCCAGA GCAGAGCCAG CGCCGACTTT GGGGCTGCAG GGAGCCCC∞ CCCACTGβGG 240
CGGCTACTGC CCAAGGTACA AGAGGTGGCC CGβTGCCTGβ GGGAGCTGCT GGCTGCAGCC 300
TGTGCCAGCC GGGCCCTGCC CCCGTCCTCC TCCGGGCCCC CCTGCCCTGC CCTGACGTCC 360
ACCTCACCCC CGGTCTGGCA GCAGCAGACC ATCCTCATGC TGAAGβAGCA βAACCGACTC 420
CTCACCCAGG AGGTGACCGA GAAGAGTGAG CGCATCACGC AGCTGβAGCA GGAGAAGTCG 480
GCGCTCATTA AGCAGCTGTT TGAGGCCCGC βCCCTGAGCC AGCAGβACGG GGGACCTCTG 540
GATTCCACCT TCATCTAGTC CTTGTβGGCC GCGTGGGCCC CCAGGGCCAG CCTGGCACTC 600
AGCCCTTCGA GGGTGGGCGC CCCATCGCAC CCACCCTCTC TGGCTGGAGA CCCCCGGCAG 660
GCCCAGGCAC AGTCCCGGAG TGGGCGCCTT CCTGCCGCCC TTGCCAGATG GGCTCCCCAG 720
GCCTGCCCCC GGCTGGTCCC CGCACCGAGC GCTTGACTCC GTTTKGGCTC CTGGTTGYTG 780
ACATGGGCTG GGGGCTCTCT TGAGTCCGCA TAGTCCGCAG CTACTACTββ CCGCTGTCAG 840
TGGACAGTGG GGTACCCCTC CATGAGTTAG CGTCCCCCCG TTTCCAβCGG TGCCGCCCTG 900
GGTCCCATCT TCAGGGAAAG GCACTGCCCA CβCCAGGCTG CACTTCCAAC AACββGCAGC 960
AGAGGGCGCG GGGCGGCTCC GACGCGGGTC CAAGGGCAGC TTCCCGCTCA ACCAGGGCAC 1020
CAGGACGAGG TGGCTGTAGC TCGGACGGAC GGAAGTAGAT GGAGGGGGTG GGGACGGCCT 1080
GTAAGCGGGG GGTGCCTGCC TGGCTGGGGA βCCCCAGGβA TAGCGGTCGG ACTTCAGGTT 1140
CTGGCCAAGG CTGAGGGACC CTGGCTGCAG CββATCGGCA CGCCβGGTGG GCGAGAGCTT 1200
GGCCTGCATG TGCCTCCCAC AGACCCTGGG GTGATGGCCT TCCCCCTCTT GGCCGGGACG 1260
TTGCCCCACG TTβAβTCCCA CACAACATCC TGTGAGCCTβ GCTCCCCAGG AGββCCCCCA 1320
GACAGCTCCC AGGCACGTCA TAGGCAAAGC CTGTTTCCCC CGACTCAGGA TTTCCAAGGC 1380
CTGGGGTCCT GCTCACCCCC CTTTGCTCTC ACβCCCAβCC TGTCCCCAGG TTTCAGCTGG 1440
GAGAGGCCAC CTCCCTCAGC CAAGGAAAAC GAGAACCCCC AGGGTACAGG AGGAGGCTGG 1500
GβCAGGTCCC CTTGGGTGTC ACTCCCTCAG CCCCTβCCCA GGCCCACTCC CGCTGβTβCT 1560
GGAGTACβCA CTGGTGGGGG GGCCCTGCTC AGCCCAACCT GGAβββTCCC AGTGTCACCA 1620
GAACCAGGGG CACGGCAACA GCATCGATGG GTTCTGCAGC CCAGββCCCC CGATGCGGGG 1680
TCAGTGTGTG TGGGGCGCAG GGCCTCCGAT GCGGGGTCAG TGCGTGGGGG GCGCAGGGCC 1740
CCCGATGCGG GGTCAGTGCG TGGGGGGCGC AGGGCCCCCT CGTGTCCAGG GCACTTTββT 1800
ACACTβTCCC ACAAGGCACC TGTCTCAGAG GAGGGGCCCT GGCAGGCAGC GTGGCAACTC 1860
CCTTCCGGAβ CCCAGCTCCA TGCTAACCTG CCCACAGCAA CCCCACAGAG CCACATTCCC 1920
TGCTGCACCT GGTCTβCAGG GGTGTCCCAG GACAGGCCCA AGTCAGCCCA GCATGCAGCT 1980
GCCCTCCTAC CCTGAAGATG GGAGTGGGCT TTCCAGGGGA CATAAGGATG TCAGGCCTGG 2040
ACCTCCTGGG CAGGAAAGGG TGCAGGTCCT GAGGGCCTGT GCCCCACAGC CCCAGCACCC 2100
AGGTGGACTG CAGCGCAGTG GGTGGGCCAG TGGCAGCCAG GGAGAAβCCC CCCGTCAGCA 2160
GGCTGGGGTC TGCCCACCAG GGCCTCCCCA CGTCTGCCTT TGAGGGTGCC TGCCATGCCC 2220
TGGGGGATCC TGGCATCTTT ACTGGACTGβ AAGCAGGAGA CAGAACAGTG TCTGTCCCGG 2280
GβTGACTTCA TCAGβAGACC βCCCACATAG AGCTGGACCC CGCAGCTGAA GCGGAAATGT 2340
GAGACAGGCT GGCACCTCCG GAAAAACTβC CTTTCAGCCT TGGTGTTCCG TGCAAGGTGA 2400
AAAβAAATAβ GTCCTCCCAG TTTACAGCTT GAAATCAGGC TAGTGAGTGG CCCTGGAGAC 2460
CACβAGGGGA GAATTTAAAG GCCCCGGCTG GCAGGGTCTA GGTGGCTGGC AGAβGCACAT 2520
GCAGACCCTG CCTGGAGCCT GCCCTAGGAC GCTGGGCGββ TCAGTCTCCG TGCAGGATGT 2580
GAGCAGCGTC CCTGGGCTCT ATCCGCGAGG TGCCAGTAGC GTGTGCAGβT ACATACACGT 2640
GCGTGCACAC TGTGATGACA CCCGGAAATG TCTCAGGATG TTGAAATβTG TCCTTGGGGG 2700
CAGAAGTGTC CCCAGTTGAβ AATCTGCCCC AGAGGAACAC ACCCACACCA GGCCTCAGGA 2760
TTTTGTGTTG ATCAAGTTCC AAGGAAAAGβ AACATCTCAβ CCGGGCGTGG TGGTTCACGC 2820 CTGGAATCCC AGCACTTGAG GCCAGGAGTT CCAGAGCAGC CTGGGCAACG CAGTGAβAβA 2880
CCCCATCTCT ACAARAAAAA AAAAAGAAAG AAAGAAAATG AGAGATCCAG GTTTAAAAAT 2940
TCATAAACAC CACAAGGAAA CAATACACTA TGAGACCCAG CAGAAGCAAC AGATTGACTC 3000
TAGACCCAGA TACTAGAATT ATCAGAGAGA ATATAAAGTA ACAGTGTTTT ATATATCTAA 3060 AGAAATAAAA GAGATTTCTG βAAACATGAA AAAAAA
A102 DNA SEQUENCE Gene name: TMPRSS3a 0 Unigene number: Hs.298241 Probeset Accession #: AIS38613 Nucleic Acid Accession #: AB038157 Coding sequence: 202-1566 (underlined sequences correspond to start and .stop codons) 5
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I I
ACCGGGCACC GβACGGCTCG GGTACTTTCG TTCTTAATTA GβTCATGCCC GTGTGAGCCA 60
GGAAAGGGCT GTGTTTAT6G GAAGCCAβTA ACACTGTGGC CTACTATCTC TTCCGTGGTG 120 0 CCATCTACAT TTTTβGGACT CGGGAATTAT GAGGTAGAGG TGGAGGCGGA GCCGGATGTC 180
AGAGGTCCTG AAATAGTCAC CATGGGβGAA AATGATCCGC CTCCTGTTGA AβCCCCCTTC 240
TCATTCCGAT CGCTTTTTCβ CCTTGATGAT TTGAAAATAA GTCCTGTTGC ACCAβATβCA 300
GATGCTGTTG CTGCACAGAT CCTGTCACTG CTGCCATTGA AGTTTTTTCC AATCATCβTC 360
ATTGGGATCA TTGCATTGAT ATTAGCACTG GCCATTGGTC TGGGCATCCA CTTCGACTGC 420 5 TCAGGGAAβT ACAGATGTCG CTCATCCTTT AAGTGTATCβ AGCTGATAGC TCGATGTGAC 480
GGAGTCTCGβ ATTGCAAAGA CGGGβAGGAC GAGTACCGCT GTGTCCGGGT GGGTGGTCAG 540
AATGCCGTGC TCCAGGTGTT CACAGCTGCT TCGTGGAAGA CCATGTGCTC CGATGACTGG 600
AAGGGTCACT ACGCAAATGT TGCCTGTGCC CAACTGGGTT TCCCAAGCTA TGTGAGTTCA 660
GATAACCTCA GAGTGAGCTC GCTGGAGGGG CAGTTCCββG AGGAGTTTGT GTCCATCGAT 720 0 CACCTCTTGC CAGATGACAA GGTGACTGCA TTACACCACT CAβTATATβT GAGGGAβββA 780
TβTGCCTCTG GCCACGTGβT TACCTTGCAG TβCACAGCCT GTββTCATAβ AAGGGGCTAC 840
AGCTCACGCA TCGTGGGTGG AAACATGTCC TTβCTCTCGC AGTGGCCCTG GCAGGCCAGC 900
CTTCAGTTCC AGββCTACCA CCTGT6C6GG GGCTCTGTCA TCACGCCCCT βTGGATCATC 960
ACTGCTGCAC ACTGTGTTTA TGACTTβTAC CTCCCCAAGT CATGGACCAT CCAGGTGGGT 1020 5 CTAGTTTCCC TGTTGGACAA TCCAGCCCCA TCCCACTTGG TGGAGAAGAT TGTCTACCAC 1080
AGCAAGTACA AGCCAAAGAG GCTGGGCAAT GACATCGCCC TTATGAAGCT GβCCGGGCCA 1140
CTCACGTTCA ATGAAATGAT CCAGCCTGTG TGCCTGCCCA ACTCTGAAGA GAACTTCCCC 1200
GATGGAAAAG TβTGCTββAC GTCAGGATGG GGGGCCACAG AGGATGGAGC AGGTGACGCC 1260
TCCCCTGTCC TGAACCACGC GGCCGTCCCT TTGATTTCCA ACAAGATCTG CAACCACAGG 1320 0 GACGTGTACG GTGβCATCAT CTCCCCCTCC ATGCTCTGCG CGGGCTACCT GACGGGTGGC 1380
GTGGACAGCT GCCAGGGGGA CAGCGGGGGG CCCCTGGTGT GTCAAGAGAG GAGGCTGTGβ 1440
AAGTTAGTβG GAGCGACCAG CTTTGGCATC GGCTGCGCAG AGGTGAACAA GCCTGGGGTG 1500
TACACCCGTG TCACCTCCTT CCTGGACTGG ATCCACGAGC AGATGβAβAβ AGACCTAAAA 1560
ACCTGAAGAG GAAGGGGACA AGTAGCCACC TGAGTTCCTG AGGTGATGAA GACAGCCCGA 1620 5 TCCTCCCCTG GACTCCCGTG TAGβAACCTG CACACGAGCA GACACCCTTG GAGCTCTGAG 1680
TTCCGGCACC AGTAGCAGGC CCGAAAGAGG CACCCTTCCA TCTGATTCCA GCACAACCTT 1740
CAAGCTGCTT TTTGTTTTTT GTTTTTTTGA GGTGGAGTCT CGCTCTGTTG CCCAGGCTGG 1800
AGTGCAGTGG CGAAATCCCT GCTCACTGCA GCCTCCGCTT CCCTGGTTCA AGCGATTCTC 1860
TTGCCTCAGC TTCCCCAGTA βCTGGGACCA CAGGTGCCCG CCACCACACC CAACTAATTT 1920 0 TTGTATTTTT AGTAGAGACA GGGTTTCACC ATGTTGGCCA GGCT6CTCTC AAACCCCTGA 1980
CCTCAAATGA TGTGCCTGCT TCAGCCTCCC ACAGTGCTβG GATTACAGGC ATGGGCCACC 2040
ACGCCTAGCC TCACGCTCCT TTCTGATCTT CACTAAβAAC AAAAGAAGCA GCAACTTGCA 2100
AGGGCGGCCT TTCCCACTββ TCCATCTβGT TTTCTCTCCA GGGβTCTTGC AAAATTCCTG 2160
ACGAGATAAG CAβTTATGTG ACCTCACGTG CAAAGCCACC AACAGCCACT CAGAAAAGAC 2220 5 GCACCAGCCC AGAAGTGCAG AACTGCAGTC ACTGCACGTT TTCATCTCTA GGGACCAGAA 2280
CCAAACCCAC CCTTTCTACT TCCAAGACTT ATTTTCACAT GTGGGGAGGT TAATCTAGGA 2340
ATGACTCGTT TAAGGCCTAT TTTCATGATT TCTTTGTAGC ATTTGGTGCT TGACGTATTA 2400
TTGTCCTTTβ ATTCCAAATA ATATGTTTCC TTCCCTCAAA AAAAAAAAAA . AAAAAAAAAA 2460
AAAAAAAA 0
A103 Protein sequence : Gene name : TMPRSS3a
, . Unigene number: Hs .298241 5 Probeset Accession # : AI538613
Protein Accession # : BAB20077 Signal sequence : none found Transmembrane domains : 43 -65 , 239-261 Tryp_SPc domain: 216-444
/0 Cellular Localization: plasma membrane
11 21 31 41 51 5 I I I I I
MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP IIVIGIIALI 60 LALAIGLGIH FDCSGKYRCR SSFKCIELIA RCDGVSDCKD GEDEYRCVRV GGQNAVLQVF 120 TAASWKTMCS DDWKGHYANV ACAQLGFPSY VSSDNLRVSS LEGQFREEFV SIDHLLPDDK 180 VTALHHSVYV REGCASGHW TLQCTACGHR RGYSSRIVGG NMSLLSQWPW QASLQFQGYH 240 LCGGSVITPL WIITAAHCVY DLYLPKSWTI QVGLVSLLDN PAPSHLVEKI VYHSKYKPKR 300
80 LGNDIALMKL AβPLTFNEMI QPVCLPNSEE NFPDGKVCWT SGWβATEDGA GDASPVLNHA 360 AVPLISNKIC NHRDVYGGII SPSMLCAGYL TGβVDSCQGD SGGPLVCQER RLWKLVGATS 420 FGIGCAEVNK PGVYTRVTSF LDWIHEQMER DLKT A104 DNA SEQUENCE βene name: Homo sapiens β protein-coupled receptor (HOT7T175)
Unigene number: Hs.208229
Probeset Accession #: AI819198
Nucleic Acid Accession #: NM_032551.1
Coding sequence: 1-1197 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
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ATGCACACCG TGGCTACβTC CGGACCCAAC GCGTCCTGGG GGGCACCGGC CAACGCCTCC 60
GGCTGCCCGG GCTGTGβCGC CAACGCCTCG GACGGCCCAG TCCCTTCGCC GCGGGCCGTG 120
GACGCCTGGC TCGTGCCGCT CTTCTTCGCG GCGCTGATGC TGCTGGGCCT GGTGGGGAAC 180
TCβCTGGTCA TCTACGTCAT CTGCCGCCAC AAGCCGATGC GGACCGTGAC CAACTTCTAC 240
ATCGCCAACC TGGCGGCCAC GGACGTGACC TTCCTCCTGT GCTGCGTCCC CTTCACGGCC 300
CTGCTGTACC CGCTGCCCGG CTGGGTGCTG GGCGACTTCA TGTGCAAGTT CGTCAACTAC 360
ATCCAGCAGG TCTCGGTGCA GGCCACGTGT GCCACTCTGA CCGCCATGAG TGTGGACCGC 420
TGGTACGTGA CGGTGTTCCC GTTGCGCGCC CTGCACCGCC GCACβCCCCG CCTGGCGCTG 480
GCTGTCAGCC TCAGCATCTG GGTAGGCTCT GCGGCGGTGT CTGCGCCGGT GCTCGCCCTG 540
CACCGCCTGT CACCCGGGCC GCGCGCCTAC TGCAGTGAGG CCTTCCCCAβ CCβCGCCCTG 600
GAGCGCGCCT TCGCACTGTA CAACCTGCTG GCGCTGTACC TGCTGCCGCT GCTCGCCACC 660
TGCβCCTGCT ATGCGGCCAT GCTGCGCCAC CTGGGCCGGG TCGCCGTGCG CCCCGCGCCC 720 βCCGATAGCG CCCTGCAGGG GCAGGTGCTG GCAGAGCGCG CAGGCGCCGT GCGGGCCAAG 780
GTCTCGCGGC TGβTGGCGGC CGTGGTCCTG CTCTTCGCCG CCTGCTGGGG CCCCATCCAG 840
CTGTTCCTGG TGCTGCAGGC GCTGGGCCCC βCGGGCTCCT GGCACCCACG CAGCTACGCC 900
GCCTACGCGC TTAAGACCTG GGCTCACTGC ATGTCCTACA GCAACTCCGC βCTGAACCCG 960
CTGCTCTACG CCTTCCTGGG CTCGCACTTC CGACAGGCCT TCCGCCGCGT CTGCCCCTGC 1020
GCGCCGCGCC GCCCCCGCCG CCCCCGCCGG CCCGGACCCT CGGACCCCGC AGCCCCACAC 1080
GCGGAGCTGC ACCGCCTGGβ GTCCCACCCG GCCCCCGCCA GGGCGCAGAA GCCAGGGAGC 1140 AGTGGGCTGG CCGCGCGCGG GCTGTGCGTC CTGGGGGAGG ACAACGCCCC TCTCTGA
A105 Protein sequence Gene name: Homo sapiens G protein-coupled receptor (HOT7T175) , mRNA Unigene number: HS.208229 Protein Accession #: AI819198 Signal sequence : none found Pfam domains: 7tra_l [59-323] Transmembrane domains : 43-65, 86-108, 122-144, 159-181, 203-225, 260-282 Cellular Localization: plasma membrane
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MHTVATSGPN ASWGAPANAS GCPGCGANAS DGPVPSPRAV DAWLVPLFFA ALMLLGLVGN 60
SLVIYVICRH KPMRTVTNFY IANLAATDVT FLLCCVPFTA LLYPLPGWVL GDFMCKFVNY 120
IQQVSVQATC ATLTAMSVDR WYVTVFPLRA LHRRTPRLAL AVSLSIWVGS AAVSAPVLAL 180
HRLSPGPRAY CSEAFPSRAL ERAFALYNLL ALYLLPLLAT CACYAAMLRH LGRVAVRPAP 240
ADSALQGQVL AERAGAVRAK VSRLVAAWL LFAACWGPIQ LFLVLQALGP AGSWHPRSYA 300
AYALKTWAHC MSYSNSALNP LLYAFLGSHF RQAFRRVCPC APRRPRRPRR PGPSDPAAPH 360 AELHRLGSHP APARAQKPGS SGLAARGLCV LGEDNAPL
A106 DNA SEQUENCE Gene name: integrin, beta 8 Unigene number: Hs.52620 Probeset Accession #: AA479726 Nucleic Acid Accession #: NM_002214 Coding sequence: 680-2990 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
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CCCAGAGCCG CCTCCCCCTG TTGCTGGCAT CCCGAGCTTC CTCCCTTGCC AGCCAGGACG 60
CTGCCGACTT GTCTTTGCCC GCTGCTCCGC AGACGGGGCT βCAAAGCTGC AACTAATGβT 120
GTTGGCCTCC CTGCCCACCT GTGGAAGCAA CTGCGCTβAT TGATGCGCCA CAGACTTTTT 180
TCCCCTCGAC CTCGCCββCG TACCCTCCCA CAGATCCAGC ATCACCCAGT GAATGTACAT 240
TAβGGTβGTT TCCCCCCCAG CTTCGGGCTT TGTTTGGGTT TGATTβTGTT TGGCTCTTCG 300
CTAAGCTGAT TTATGCAGCA GAAGCCCCAC CGGCTGGAGA GAAACAAAAG CTCTTTTCTT 360
TGTCCCGGAG CAGGCTGCGG AGCCCTTGCA GAGCCCTCTC TCCAGTCGCC GCCGGGCCCT 420
TGGCCGTCGA AGGAGGTGCT TCTCGCGGAG ACCGCGGGAC CCGCCGTGCC GAGCCGGGAG 480
GGCCβTAGGG GCCCTGAGAT GCCGAGCGGT GCCCGGGCCC GCTTACCTGC ACCGCTTGCT 540
CCGAGCCGCG GGGTCCGCCT GCTAGGCCTG CGGAAAACGT CCTAGCGACA CTCGCCCGCG 600
GGCCCCGAGG TCGCCCGGGA GGCCGAGCCC βCGTCCGGAA GGCAGCCAGG CGGCGGGCGC 660
GGGGCGGGCT GTTTTGCATT ATGTGCGβCT CGGCCCTGGC TTTTTTTACC GCTGCATTTG 720
TCTGCCTGCA AAACGACCGG CGAGGTCCCG CCTCGTTCCT CTββGCAGCC TGGGTGTTTT 780
CACTTGTTCT T6GACTGGGC CAAGGTGAAG ACAATAGATG TGCATCTTCA AATGCAGCAT 840
CCTGTGCCAG GTGCCTTGCG CTGGGTCCAβ AATGTGGATG βTGTGTTCAA GAGGATTTCA 900
TTTCAGGTGG ATCAAGAAGT GAACGTTGTG ATATTGTTTC CAATTTAATA AGCAAAGβCT 960
GCTCAGTTGA TTCAATAGAA TACCCATCTG TGCATGTTAT AATACCCACT GAAAATGAAA 1020
TTAATACCCA GGTGACACCA GGAGAAGTGT CTATCCAGCT GCGTCCAβGA GCCGAAGCTA 1080
ATTTTATGCT GAAAGTTCAT CCTCTβAAGA AATATCCTGT GGATCTTTAT TATCTTGTTG 1140
ATGTCTCAGC ATCAATGCAC AATAATATAG AAAAATTAAA TTCCGTTGGA AACGATTTAT 1200
CTAGAAAAAT GGCATTTTTC TCCCGTGACT TTCGTCTTββ ATTTGGCTCA TACGTTGATA 1260
AAACAGTTTC ACCATACATT AGCATCCACC CCGAAAGGAT TCATAATCAA TGCAGTGACT 1320
ACAATTTAGA CTGCATGCCT CCCCATGGAT ACATCCATGT GCTGTCTTTG ACAGAGAACA 1380
TCACTGAGTT TGAGAAAGCA GTTCATAGAC AGAAGATCTC TGGAAACATA GATACACCAG 1440 AAGGAGGTTT TGACGCCATC CTTCAGGCAG CTGTCTGTGA AAGTCATATC GGATGGCGAA 1500
AAβAGGCTAA AAGATTGCTG CTGGTGATGA CAGATCAGAC GTCTCATCTC GCTCTTGATA 1560
GCAAATTGGC AGGCATAGTG GTGCCCAATG ACGGAAACTG TCATCTGAAA AACAACGTCT 1620
ACGTCAAATC GACAACCATG GAACACCCCT CACTAGGCCA ACTTTCAβAβ AAATTAATAG 1680
ACAACAACAT TAATGTCATC TTTGCAGTTC AAGGAAAACA ATTTCATTGG TATAAGGATC 1740
TTCTACCCCT CTTGCCAGβC ACCATTGCTG GTβAAATAGA ATCAAAGGCT GCAAACCTCA 1800
ATAATTTGGT AGTGGAAGCC TATCAGAAGC TCATTTCAGA AGTβAAAGTT CAGGTGGAAA 1860
ACCAGGTACA AGGCATCTAT TTTAACATTA CCGCCATCTβ TCCAGATGββ TCCAGAAAGC 1920
CAGGCATGGA AGGATGCAGA AACGTGACGA βCAATGATGA AβTTCTTTTC AATGTAACAG 1980 0 TTACAATGAA AAAATGTGAT GTCACAGβAG GAAAAAACTA TGCAATAATC AAACCTATTG 2040
GTTTTAATGA AACCGCTAAA ATTCATATAC ACAGAAACTG CAGCTGTCAG TGTGAGGACA 2100
ACAGAGGACC TAAAβGAAAG TGTGTAGATG AAACTTTTCT AGATTCCAAG TGTTTCCAGT 2160
GTGATGAGAA TAAATGTCAT TTTGATGAAG ATCAβTTTTC TTCTGAGAGT TGCAAGTCAC 2220
ACAAGGATCA GCCTGTTTGC AGTGGTCGAG GAGTTTβTGT TTGTβGGAAA TGTTCATGTC 2280 5 ACAAAATTAA GCTTGβAAAA GTβTATGGAA AATACTGTGA AAAGGATβAC TTTTCTTGTC 2340
CATATCACCA TGGAAATCTG TGTβCTGGGC ATGβAβAGTG TGAAGCAGGC AGATGCCAAT 2400
GCTTCAGTβG CTGGGAAGβT GATCGATGCC AGTβCCCTTC AGCAGCAβCC CAGCACTGTG 2460
TCAATTCAAA GGGCCAAGTG TGCAGTGGAA GAGGCACGTG TGTGTGTGGA AGGTGTGAGT 2520
GCACCGATCC CAGGAGCATC GGCCGCTTCT GTGAACACTG CCCCACCTGT TATACAGCCT 2580 0 GCAAGGAAAA CTGGAATTGT ATGCAATGCC TTCACCCTCA CAATTTGTCT CAGGCTATAC 2640
TTGATCAGTG CAAAACCTCA TGTGCTCTCA TββAACAACA GCATTATGTC GACCAAACTT 2700
CAGAATGTTT CTCCAGCCCA AGCTACTTGA βAATATTTTT CATCATTTTC ATAGTTACAT 2760
TCTTGATTGG GTTGCTTAAA GTCCTGATCA TTAGACAGGT GATACTACAA TGGAATAGTA 2820
ATAAAATTAA GTCCTCATCA GATTACAGAG TGTCAGCCTC AAAAAAGGAT AAGTTGATTC 2880 5 TGCAAAGTGT TTGCACAAGA GCAGTCACCT ACCGACGTGA βAAGCCTGAA GAAATAAAAA 2940
TGGATATCAG CAAATTAAAT GCTCATGAAA CTTTCAGGTG CAACTTCTAA AAAAAGATTT 3000
TTAAACACTT AATGGGAAAC TGGAATTGTT AATAATTGCT CCTAAAGATT ATAATTTTAA 3060
AAGTCACAGG AGGAGACAAA TTGCTCACGG TCATGCCAGT TβCTGGTTGT ACACTCGAAC 3120
GAAGACTGAC AAGTATCCTC ATCATGATGT GACTCACATA GCTGCTGACT TTTTCAGAGA 3180 0 AAAATGTGTC TTACTACTGT TTGAGACTAG TGTCCTTGTA GCACTTTACT GTAATATATA 3240
ACTTATTTAG ATCAGCATAG AATGTAβATC CTCTGAAGAG CACTGATTAC ACTTTACAGβ 3300
TACCTGTTAT CCCTACGCTT CCCAGAGAβA ACAATGCTGT GAGAGAβTTT AGCATTGTGT 3360
CACTACAAGG GTACAGTAAT CCCTGCACTG GACATGTGAG GAAAAAAATA ATCTGGCAAG 3420
TATATTCTAA GGTTGCCAAA CACTTCAACA GTTGGTGβTT GAATAGACAA βAACAβCTAβ 3480 5 ATGAATAAAT GATTCGTGTT TCACTCTTTC AAGAGGTβAA CAGATACAAC CTTAATCTTA 3540
AAAGATTATT GCTTTTTAAA GTGTGTAGTT TTATGCATGT GTβTTTATGG TTTβCTTATT 3600
TTTGCAAGAT GGATACTAAT TCCAGCATTC TCTCCTCTTT GCCTTTATGT TTTβTTTTCT 3660
TTTTTACAGG ATAAGTTTAT GTATGTCACA GATGACTGGA TTAATTAAGT βCTAAGTTAC 3720
TACTGCCATA AAAAACTAAT AATACAATGT CACTTTATCA GAATACTAGT TTTAAAAGCT 3780 0 GAATGTTAA
A107 Protein sequence : Gene name : Integrin, beta 8 5 Unigene number : Hs .52620 Probeset Accession ft : AA479726 Protein Accession # : NP_002205 .1 Signal sequence : 1-39 Transmembrane domains : 682-704 0 EGF domain: 552-584 INB domain: 54-469 Cellular Localization: plasma membrane 5
11 21 31 41 51
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MCGSALAFFT AAFVCLQNDR RβPASFLWAA WVFSLVLGLG QGEDNRCASS NAASCARCLA 60 LGPECGWCVQ EDFISGGSRS ERCDIVSNLI SKGCSVDSIE YPSVHVIIPT ENEINTQVTP 120 0 GEVSIQLRPG AEANFMLKVH PLKKYPVDLY YLVDVSASMH NNIEKLNSVG NDLSRKMAFF 180 SRDFRLGFGS YVDKTVSPYI SIHPERIHNQ CSDYNLDCMP PHGYIHVLSL TENITEFEKA 240 VHRQKISGNI DTPEGGFDAM LQAAVCESHI GWRKEAKRLL LVMTDQTSHL ALDSKLAGIV 300 VPNDGNCHLK NNVYVKSTTM EHPSLβQLSE KLIDNNINVI FAVQβKQFHW YKDLLPLLPβ 360 TIAGEIESKA ANLNNLWEA YQKLISEVKV QVENQVQGIY FNITAICPDG SRKPβMEβCR 420 5 NVTSNDEVLF NVTVTMKKCD VTGGKNYAII KPIGFNETAK IHIHRNCSCQ CEDNRGPKβK 480 CVDETFLDSK CFQCDENKCH FDEDQFSSES CKSHKDQPVC SGRGVCVCGK CSCHKIKLGK 540 VYGKYCEKDD FSCPYHHGNL CAGHGECEAG RCQCFSGWEG DRCQCPSAAA QHCVNSKGQV 600 CSβRGTCVCG RCECTDPRSI GRFCEHCPTC YTACKENWNC MQCLHPHNLS QAILDQCKTS 660 CALMEQQHYV DQTSECFSSP SYLRIFFIIF IVTFLIGLLK VLIIRQVILQ WNSNKIKSSS 720 0 DYRVSASKKD KLILQSVCTR AVTYRREKPE EIKMDISKLN AHETFRCNF
A108 DNA sequence Gene name: ESTs Unigene number: Hs.128899 I Probeset Accession ft: AA983251
Nucleic Acid Accession AA983251 Coding seguence : 1-1749 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 0
A ITGC'TGTCTG GICTTCTTGAT GIAGTCCCAGT AICCCAGCACA GIAGCACAGTA CIACTCCCGGA 60
GGAAAβAAAC TTCCβTGGβA GGCTTCCATC GGTGCGCACA CCTCCCGAGG GCGAGβCAβC 120
GACCGGGAβA GGGAGAGCCG GCCGGAGGCT GCCGGGCTCC TGTGGGACCG CGCTGCAGCC 180 βGGGAGGCGβ AGAAGGGGAA CCGGGGCGAG CCGCCCGCCT GGATCCGCGC CCAGCAGCAG 240 CCGCGGCCGC CGCCAGCTGβ GCAGGCTCCC GGGACTGCCβ CTGGGGGCGC GCAGGACCCT 300
CGCCTβCGTC CTGGACGTTC CCGGGGβAGG GTCCGGTTGC CAGTGAAACC TCCAGAGGCT 360
TCCGGACGAC AβCCCCGGGG GCCTTCTGAC TGCATCCCGA GATTTCCATC AGCGAGTGCA 420
ACTCATAAβG CAGTCCCTAA βGGGACCβGG CCACCGGCTG AGGACββββA TGβCTTAGGA 480
GCTCCTGβAC CTAGGβCCCβ GCGTCGTCGC CTCCTGGGCG TCGCGGCA6A GGGGAGTGGC 540
CCGCGCGβAA AGCGCCGCGβ GACAGTCAGT GACGAGGCCC GGGGGTCGCC GGGβCCACGA 600
CTTCTCGGAG ACCGTCCTGC GCTCTCTββA GACGCGCTGT CCGCGCCCAβ βGTGGTGCCA 660
TGTGGGGCGC TCGCCGCTCG TCCGTCTCCT CATCCTGβAA CGCCβCTTCβ CTCCTGCAGC 720
TβCTGCTGGC TGCGCTGCTG GCGβCCβGGG CGAGGCCCCA GCGGCGAGTA CTGCCACGGC 780
TCGCTGGACG CβCAGGGCGT CTGGCGCATC GβCTTCCAGT GTCCCGAGCC CTTCGACGGC 840
GGCGACGCCA CCATCTGCTG CGGCAGCTGC GCβTTβCβCT ACTGCTGCTC CAGCGCCGAG 900
GCGCGCCTGG ACCAGGGCGβ CTGCGACAAT GACCβCCAGC AGGGCGCTGG CGAβCCTGGC 960
CGGGCGGACA AAGACCGGCC CCGACGGCTC GGCAβGGCTT CATGTCTTAG GββTACCCAA 1020 ββAGACGGCG AGβGTGCGCC CCCACCCGTG AGGβCCTGGC AGCGGTGCTC CCCTGAAGGC 1080
TCCCCGAAAG GAAβGCAGCT CCTCAGGGCT TTCCCGGGGC TGCTGCCCCG TGCCAGACGC 1140
CGCGGATTCC CATCTTCTCC ACGCGGCGGC CCCTCTCCCC TGCAGCGGCC CGCCTTGCCC 1200
ATCTACGTGC CGTTCCTCAT TGTTGGCTCC GTGTTTβTCG CCTTTATCAT CTTGGβGTCC 1260
CTGGTGGCAG CCTGTTGCTβ CAGATGTCTC CGβCCTAAGC AGGATCCCCA GCAGAGCCGA 1320
GCCCCAGβββ GTAACCGCTT GATGGAGACC ATCCCCATGA TCCCCAGTGC CAGCACCTCC 1380
CGGGGGTCGT CCTCACGCCA GTCCAGCACA GCTβCCAβTT CCAGCTCCAG CβCCAACTCC 1440
CGGGCCCGGG CGCCCCCAAC AAGGTCACAG ACCAACTCTT GCTTGCCGGA AGGGACCATG 1500
AACAACGTGT ATGTCAACAT GCCCACGAAT TTCTCTGTGC TGAACTGTCA GCAββCCACC 1560
CAGATTGTGC CACATCAAβG GCAGTATCTG CATCCCCCAT ACβTGGGGTA CACGGTβCAC 1620
CACGACTCTG TGCCCATGAC AGCTGTGCCA CCTTTCATGG ACGGCCTβCA GCCTGGCTAC 1680
AGGCAGATTC AGTCCCCCTT CCCTCACACC AACAβTβAAC AGAAGATGTA CCCAGCGGTG 1740
ACTGTATAAC CGAGAGTCAC TGGTGGGTTC CTTTACTGAA GGGAGACGAA GGCAGGGGTG 1800
GATTCTCGAG GTβGAAGTCC GCACATβTCG GTGGTATTTA TGGCACGATT CCTTTGGATG 1860
GCTTCATTTG CCCCCAGACT GTATGAAAAC ATCTCCGAAT TAGCATTTCT GβATATGTTT 1920
CATCCAGGβT ATCATTGATT TATGATGGAA AACCGGCCTC AGCTGGAGAT GACTGTGATG 1980
TTGCTGATGβ GTGTATAACA AATGCTTGAG TCCGAAGTGC CCTTGAGATA TGβTTGACGA 2040
AAGAATTTTA TAAACTGATA AATTAAGGAT TTTTATTATG TT6TTATTAT TATTTCTTTT 2100
TTGTTGTTGA CTGCACACGA TCAAAATGCC TGTTATCTCC CTTTTACTGG GACTTTTTTT 2160 ττττττττττ TTTTTTTTAA TCAGACAGββ TCTTGCTCTG TTGCCCAGGC TGGAGTβCAβ 2220
TGGTGCGATC TCGGCTCACT GCAACTTCAG CCTCCTGGAT TCAGGCAACA CTCCTβCCTC 2280
AGCCTCCCAC GTGGCTGGGA TTACAGGTGC CTGCCCCCAT GGCTAATTTT TTGTATTTTT 2340
TGTAGAβATG GGGTTTCACC ATGTTGGCTG GGCTG6TCTC ACTCTCCTGA CCTCAAβCAA 2400
TCTGCCTGTC TCAGCCTCCC AAAGTGCTGG GATTACAGGC GTGAGCCACC GCCCCCAGCC 2460
TGAGCCTTTT TTTTTTTCTA ATGCATCCAA GβTTAAGGGG AAGACGCAAA TAACAGGACT 2520
ATTCTAAAAG GAAACCTGTT TGAACTCTGT GAGATCAGTC ATCAGTCTCA GTATTCCACA 2580
GGCACACCTT AATTTCATTG TAAAAAGATA TATATATTTT βTCTATTTTT GTGCTTTTGG 2640
GGGCCTATTT TGTβCTTTTT TACCTTATβT AGAGATCTTA TTACAAAGTG ATTTTCTACA 2700
TTAAAAAGAG ACTGAAATAA ATTGTATAGT TACTTAACTA ATGAAGACAT TTCAGAACTC 2760
TGGGATGATT TTAATCTTGA AGTAGTAGGT GGTATAGTCA TAAAACCATT CATCCCCTTC 2820
TTGATTGTAT CTTAATTTTC TGGCTTTAAG GTGACATCTG AGA6GTAATG CATTCTTTTT 2880
TATATTGAAA TCATAAACTA TCACCCGCTG CTTCTCTGAG TTACTTTTAA TTTTGCCTTβ 2940
TGGTTATGβT TTGGCGTTTC CTTCTGTTTG GTTTTCAGAβ CCCCATGTCT ATATAGTCCT 3000 βAGTGCAAGT AATTACTATA CTTGTAAATG AAGATCAGTA TTTCTGCCTA GATCTGATAA 3060
AAAAATTTTC TTGTCTTAGT TATAAAAATT CAAAGAAATG TGTTACAAAβ ATACTTAGTA 3120
TAGCTCCTCA GCCATAACCT GAGACTTGGβ ATβAAATTTA AACCAGATAC GATTTACTTT 3180
GCAGATCATA AGGCTTTTTA TACTCTTGTT ATCAAAATGβ CTTATTTTTC AGGCACTAAG 3240
GATTGTTAAG AGAAAAGCTT TTCAACβAAG GATTGCCTTT CTTCTCCCAC ACTGTTCTTG 3300
ATTTCCTCTC TCTTTCAGGC CTCAACAGβC ACTGTATTCA TTGCCAATGT TCCAAATTAT 3360
CAAATTCAAG TGAATTTATT TβTGTGTTCT TTACTTATAT AAAAAAAGAT AACTTTAAGG 3420
ATGTGCAAGT ACATTTCCAA CTGCTAGCAC AACCAGTATT TTGTAATTAA ACAAATCGCT 3480
GTATββTATG GTCTTCTACA CATTTATGTC TATAGATATC TATCGATCAT CTTTCTATTC 3540
TGTTTCATGA CTGAATAATG TAAAACCAGT GTTGGCAATT GGTATCATCA ATGATACTCA 3600
TTTTTTAATA ACCAAAGGCA GGGGAAAATC ATTTTACTTA TTAATAAATA TTTTATGATG 3660
TGAAAAAAAA AAAAAAAAAA AAAAAAAAAA
A109 Protein sequence
Gene name : ESTs
Unigene number : Hs .128899
Protein Accession ft : none found
Signal sequence : 1 - 11
Transmembrane domains : 402 -424
Cellular Localization: not determined
1 11 21 31 41 51 1 1 11 11 1 1 11 11 MLSGFLMSPS TQHRAQYTPG βKKLPWEASI GAHTSRGRGS DRERESRPEA AGLLWDRAAA 60 βEAEKGNRGE PPAWIRAQQQ PRPPPAGQAP βTAAGGAQDP RLRPGRSRGR VRLPVKPPEA 120
SGRQPRGPSD CIPRFPSASA THKAVPKGTG PPAEDGDGLG APGPRARRRR LLGVAAEGSG 180
PRGKRRGTVS DEARGSPGPR LLGDRPALSG DALSAPRWP CGALAARPSP HPGTPLRSCS 240
CCWLRCWRRβ RGPSGEYCHG WLDAQGVWRI GFQCPERFDG GDATICCGSC ALRYCCSSAE 300
ARLDQGGCDN DRQQGAGEPG RADKDβPRRL GRASCLRGTQ GDGEGAPPPV RAWQRCSPEβ 360
SPKGRQLLRA FPGLLPRARR RGFPSSPRGG PSPLQRPALP IYVPFLIVGS VFVAFIILGS 420
LVAACCCRCD RPKQDPQQSR APGGNRLMET IPMIPSASTS RGSSSRQSST AASSSSSANS 480
GARAPPTRSQ TNCCLPEGTM NNVYVNMPTN FSVLNCQQAT QIVPHQGQYL HPPYVGYTVQ 540
HDSVPMTAVP PFMDGLQPGY RQIQSPFPHT NSEQKMYPAV TV
A110 DNA SEQUENCE :
Gene name : ESTs , Weakly similar to JE0350 Anterior gradient -2 [H . sapiens. Unigene number: Hs.100686 Probeset Accession #: AA487468 Nucleic Acid Accession #: AA487468 Coding sequence: 55-555 (underlined sequences correspond to start and stop codons)
60
120
180
Figure imgf000885_0001
240
ATGGTTATTC ATCACCTGGA GGATTGTCAA TACTCTCAAG CACTAAAGAA AGTATTTGCC 300
CAAAATGAAG AAATACAAGA AATGGCTCAG AATAAGTTCA TCATGCTAAA CCTTATGCAT 360 βAAACCACTG ATAAGAATTT ATCACCTCAT GGGCAATATG TβCCTAGAAT CATGTTTGTA 420
GACCCTTCTT TAACAGTTAG AβCTβACATA GCTGGAAGAT ACTCTAACAG ATTGTACACA 480
TATGAGCCTC GGGATTTACC CCTATTGATA GAAAACATGA AGAAAGCATT AAGACTTATT 540
CAGTCAGAGC TATAAGAGAT GATAGAAAAA AβCCTTCACT TCAAAGAAβT CAAATTTCAT 600
GAAGAAAACC TCTGGCACAT TGACAAATAC TAAATGTGCA AGTATATAGA TTTTGTAATA 660
TTACTATTTA GTTTTTTTAA TGTGTTTβCA ATAGTCTTAT TAAAATAAAT GTTTTTTAAA 720
TCTGAAAAAA AAAAAAAAAA AAAAAAAAA
Alll Protein sequence: Gene name : ESTs, Weakly similar to JE0350 Anterior gradient-2 [H.sapiens] Unigene number: Hs.100686 Probeset Accession ft: AA487468 Protein Accession ft: none found Signal sequence : 1-23 Transmembrane domains: none found Cellular Localization: secreted
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MMLHSALGLC LLLVTVSSNL AIAIKKEKRP PQTLSRGWGD DITWVQTYEE GLFYAQKSKK 60 PLMVIHHLED CQYSQALKKV FAQNEEIQEM AQNKFIMLNL MHETTDKNLS PDGQYVPRIM 120 FVDPSLTVRA DIAGRYSNRL YTYEPRDLPL LIENMKKALR LIQSEL
A112 DNA SEQUENCE
Gene name: Homo sapiens type II membrane serine protease mRNA
Unigene number: Hs.63325
Probeset Accession ft: AA411502
Nucleic Acid Accession ft: NM_016425
Coding sequence: 1-1314 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
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ATGTTACAββ ATCCTGACAG TGATCAACCT CTGAACAGCC TCGATGTCAA ACCCCTGCCC 60 AAACCCCGTA TCCCCATββA GACCTTCAGA AAGβTGGβGA TCCCCATCAT CATAβCACTA 120 CTGAGCCTGG CβAβTATCAT CATTGTGGTT GTCCTCATCA AGGTGATTCT GGATAAATAC 180 TACTTCCTCT CCβGGCAGCC TCTCCACTTC ATCCCGAGGA AGCAβCTGTG TGACGGAGAG 240 CTGGACTGTC CCTTGGGGβA GGACGAGGAG CACTGTGTCA AGAGCTTCCC CGAAGβGCCT 300 GCAGTGGCAG TCCGCCTCTC CAAGGACCGA TCCACACTGC AGGTGCTGGA CTCββCCACA 360 GGGAACTGGT TCTCTGCCTG TTTCGACAAC TTCACAGAAG CTCTCGCTGA GACAβCCTGT 420 AGGCAGATGG GCTACAGCAG CAAACCCACT TTCAGAGCTG TGGAGATTGβ CCCAGACCAG 480 GATCTGGATG TTGTTGAAAT CACAGAAAAC AGCCAGGAGC TTCβCATβCG GAACTCAAGT 540 GGGCCCTGTC TCTCAGGCTC CCTGGTCTCC CTGCACTGTC TTGCCTGTGG GAAGAGCCTG 600 AAβACCCCCC GTGTGβTGGG TGGGGAβGAG GCCTCTβTGG ATTCTTGGCC TTGβCAGGTC 660 AβCATCCAβT ACGACAAACA GCACβTCTβT GGAGGGAβCA TCCTGGACCC CCACTGGGTC 720 CTCACGGCAG CCCACTGCTT CAGGAAACAT ACCGATGTGT TCAACTGGAA GGTGCGGGCA 780 GGCTCAGACA AACTGGGCAG CTTCCCATCC CTGGCTGTGG CCAAGATCAT CATCATTGAA 840 TTCAACCCCA TGTACCCCAA AGACAATGAC ATCGCCCTCA TβAAGCTGCA GTTCCCACTC 900 ACTTTCTCAG GCACAGTCAβ βCCCATCTGT CTGCCCTTCT TTGATGAGGA GCTCACTCCA 960 GCCACCCCAC TCTβGATCAT TββATGGGGC TTTACGAAGC AGAATGGAGG GAAGATGTCT 1020 GACATACTβC TGCAβGCGTC AGTCCAGGTC ATTGACAGCA CACGβTGCAA TGCAGACGAT 1080 GCGTACCAGβ GββAAGTCAC CGAGAAGATβ ATGTGTGCAG GCATCCCGGA AGGGGGTGTG 1140 GACACCTGCC AGGβTGACAG TββTβββCCC CTGATGTACC AATCTGACCA GTGGCATGTG 1200 GTGGGCATCG TTAβCTββGG CTATGGCTGC GGGGGCCCGA GCACCCCAGG AGTATACACC 1260 AAGGTCTCAG CCTATCTCAA CTGGATCTAC AATβTCTGGA AGβCTGAGCT GTAA
A113 Protein sequence: Gene name : Homo sapiens type II membrane serine protease mRNA Unigene number: Hs.63325 Probeset Accession ft: AA411502 Protein Accession #: NP_057509 Signal sequence-. none found Transmembrane domains: 31-53 LDLa domain: 54-94 Tryp_SPc domain: 204-429 Cellular Localization: plasma membrane/ER 1 11 21 31 41 51 i 1 i1 i1 1 1 1 1 | 1
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIW VLIKVILDKY 60
YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT 120
GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDWEITEN SQELRMRNSS 180
GPCLSGSLVS LHCLACβKSL KTPRWGGEE ASVDSWPWQV SIQYDKQHVC GGSI DPHWV 240
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL 300
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGβKMS DILLQASVQV IDSTRCNADD 360
AYQGEVTEKM MCAGIPEGGV DTCQβDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT 420
KVSAYLNWIY NVWKAEL
All4 DNA SEQUENCE:
Gene name: TTK protein kinase Unigene number: HS.169840 Probeset Accession ft: M86699 Nucleic Acid Accession #: NM_003318 Coding sequence: 1026-3551 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I I
GGAATTCCTT TTTTTTTTTT TTTGAGATGG AβTTTCACTC TTGTTGβCCA GGCTGGAGTG 60 CAATβGCACA ATCTCAGCTT ACTGCAACCT CCGCCTCCCβ GGTTCAAGCG ATTCTCCTGC 120 CTCAGCCTCT CAAGTAGCTG GGATTACAGG CATGTGCCAC CACCCCTGβC TAACTAATTT 180 CTTTTCTATT TAβTAGAGAT GGGGTTTCAC CATGTTGGTC AGβCTGGTCT TGAACTCCTG 240 ACCTCAGGTG ATCCACTTGC CTTGGCCTCC CAAAβTβCTA GGATTACAGC CβTGAAACTG 300 TGCCTGGCTG ATTCTTTTTT T6TTGTTGGA TTTTTGAAAC AGGGTCTCCC TTββTCGCCC 360 AGβCTGGAGT GCAGTGGTGC GATCTTGGCT CACTATAACC TCCACCTCCT GβTTTCAAβT 420 GATCCTCCCA CTTTAGCCTC CTGAGTAGCT GTGATTACAG GCGTβCACCA CCACACCCGβ 480 CTAATTTTTβ TATTTTTATT AGAGACAGGG TTTCACCATG TTGGCCAGGC TGTTCTCAAA 540 CTCCTGGACT CAAGββATCC βCCTGCCTCC ACTTCCCAAA GTCCCGAGAT TACAGGTGTG 600 AβTCACCATβ CCTGACCTTA TAATTCTTAA GTCATTTTTT CTGGTCCATT TCTTCCTTAG 660 GGTCCTCACA ACAAATCTGC ATTAGGCGGT ACAATAATCC TTAACTTCAT GATTCACAAA 720 AGGAAGATGA AGTGATTCAT GATTTAGAAA GGGGAAGTAG TAAGCCCACT GCACACTCCT 780 GGATGATGAT CCTAAATCCA GATACAGTAA AAATGGGGTA TGGGAAGGTA GAATACAAAA 840 TTTGGTTTAA ATTAATTATC TAAATATCTA AAAACATTTT TGGATACATT GTTGATGTGA 900 ATGTAAGACT GTACAGACTT CCTAGAAAAC AβTTTGGGTT CCATCTTTTC ATTTCCCCAG 960 TGCAβTTTTC TGTAGAAATG GAATCCGAGG ATTTAAGTGβ CAGAGAATTG ACAATTGATT 1020 CCATAATGAA CAAAβTβAGA GACATTAAAA ATAAGTTTAA AAATGAAGAC CTTACTGATG 1080 AACTAAGCTT GAATAAAATT TCTGCTGATA CTACAGATAA CTCGGGAACT GTTAACCAAA 1140 TTATβATGAT GGCAAACAAC CCAGAGGACT GGTTGAGTTT GTTGCTCAAA CTAGAGAAAA 1200 ACAGTβTTCC CCTAAβTGAT GCTCTTTTAA ATAAATTGAT TGGTC6TTAC AGTCAAGCAA 1260 TTGAAGCGCT TCCCCCAGAT AAATATGβCC AAAATβAGAG TTTTGCTAGA ATTCAAGTGA 1320 βATTTβCTGA ATTAAAAGCT ATTCAAGAGC CAGATGATGC ACGTGACTAC TTTCAAATGG 1380 CCAGAGCAAA CTGCAAGAAA TTTGCTTTTG TTCATATATC TTTTβCACAA TTTGAACTGT 1440 CACAAββTAA TGTCAAAAAA AβTAAACAAC TTCTTCAAAA AGCTGTAGAA CGTGGAGCAG 1500 TACCACTAGA AATGCTGGAA ATTGCCCTGC GGAATTTAAA CCTCCAAAAA AAβCAβCTGC 1560 TTTCAGAGGA GGAAAAGAAG AATTTATCAG CATCTACGβT ATTAACTGCC CAAβAATCAT 1620 TTTCCGGTTC ACTTGGGCAT TTACAGAATA GGAACAACAG TTGTGATTCC AGAGGACAGA 1680 CTACTAAAGC CAGGTTTTTA TATGGAGAGA ACATGCCACC ACAAβATGCA GAAATAGGTT 1740 ACCGGAATTC ATTGAGACAA ACTAACAAAA CTAAACAβTC ATGCCCATTT GGAAGAGTCC 1800 CAGTTAACCT TCTAAATAGC CCAβATTGTG ATGTGAAGAC AGATGATTCA GTTGTACCTT 1860 GTTTTATGAA AAGACAAACC TCTAGATCAG AATGCCGAGA TTTGGTTGTG CCTGGATCTA 1920 AACCAAGTGG AAATGATTCC TGTGAATTAA GAAATTTAAA GTCTGTTCAA AATAGTCATT 1980 TCAAGGAACC TCTGβTGTCA GATGAAAAGA GTTCTGAACT TATTATTACT GATTCAATAA 2040 CCCTGAAGAA TAAAACGGAA TCAAGTCTTC TAGCTAAATT AGAAβAAACT AAAGAGTATC 2100 AAGAACCAGA GGTTCCAGAG AGTAACCAGA AACAGTGβCA AGCTAAGAGA AAGTCAGAGT 2160 GTATTAACCA βAATCCTβCT βCATCTTCAA ATCACTββCA GATTCCGGAG TTAGCCCGAA 2220 AAGTTAATAC AGAGCAGAAA CATACCACTT TTGAGCAACC TβTCTTTTCA GTTTCAAAAC 2280 AGTCACCACC AATATCAACA TCTAAATGGT TTGACCCAAA ATCTATTTGT AAGACACCAA 2340 GCAGCAATAC CTTGGATGAT TACATGAGCT GTTTTAGAAC TCCAGTTGTA AAGAATGACT 2400 TTCCACCTGC TTGTCAGTTG TCAACACCTT ATGGCCAACC TGCCTGTTTC CAGCAGCAAC 2460 AGCATCAAAT ACTTGCCACT CCACTTCAAA ATTTACAGGT TTTAGCATCT TCTTCAGCAA 2520 ATGAATGCAT TTCGGTTAAA GGAAGAATTT ATTCCATATT AAAGCAGATA GGAAGTGGAG 2580 GTTCAAβCAA GGTATTTCAG GTGTTAAATG AAAAGAAACA GATATATGCT ATAAAATATG 2640 TβAACTTAβA AGAAGCAGAT AACCAAACTC TTGATAGTTA CCGGAACGAA ATAGCTTATT 2700 TGAATAAACT ACAACAACAC AGTGATAAGA TCATCCGACT TTATβATTAT βAAATCACGG 2760 ACCAβTACAT CTACATGβTA ATGGAβTGTG GAAATATTGA TCTTAATAGT TGβCTTAAAA 2820 AGAAAAAATC CATTGATCCA TGββAACGCA AGAGTTACTG GAAAAATATG TTAGAGGCAG 2880 TTCACACAAT CCATCAACAT GGCATTGTTC ACAGTGATCT TAAACCAGCT AACTTTCTGA 2940 TAβTTβATGG AATGCTAAAG CTAATTGATT TTGGGATTGC AAACCAAATβ CAACCAβATA 3000 CAACAAGTGT TGTTAAAGAT TCTCAGGTTG GCACAGTTAA TTATATGCCA CCAGAAGCAA 3060 TCAAAGATAT GTCTTCCTCC AGAGAβAATβ GGAAATCTAA βTCAAAGATA AGCCCCAAAA 3120 GTGATGTTTG GTCCTTAGGA TGTATTTTGT ACTATATGAC TTACGGGAAA ACACCATTTC 3180 AGCAGATAAT TAATCAGATT TCTAAATTAC ATGCCATAAT TGATCCTAAT CATGAAATTG 3240 AATTTCCCGA TATTCCAGAG AAAGATCTTC AAGATGTGTT AAAGTGTTGT TTAAAAAGGG 3300 ACCCAAAACA GAGGATATCC ATTCCTGAGC TCCTGGCTCA TCCATATGTT CAAATTCAAA 3360 CTCATCCAGT TAACCAAATG GCCAAGGGAA CCACTGAAGA AATGAAATAT GTTCTGGGCC 3420 AACTTGTTGG TCTGAATTCT CCTAACTCCA TTTTGAAAGC TGCTAAAACT TTATATGAAC 3480 ACTATAGTGG TGGTGAAAGT CATAATTCTT CATCCTCCAA GACTTTTGAA AAAAAAAGGG 3540 GAAAAAAATG ATTTGCAGTT ATTCGTAATG TCAGATAGGA βGTATAAAAT ATATTGGACT 3600 GTTATACTCT TGAATCCCTG TββAAATCTA CATTTGAAGA CAACATCACT CTGAAGTGTT 3660 ATCAGCAAAA AAAATTCACT GAGATTATCT TTAAAAGAAA ACTGTAAAAA TAGCAACCAC 3720 TTATGGCACT GTATATATTG TAβACTTβTT TTCTCTGTTT TATGCTCTTG TGTAATCTAC 3780 TTGACATCAT TTTACTCTTG GAATAGTβββ TβGATAGCAA βTATATTCTA AAAAACTTTG 3840 TAAATAAAGT TTTGTGGCTA AAATGA
A115 Protein sequence:
Gene name: TTK protein kinase
Unigene number: Hs.169840
Probeset Accession ft: M86699
Protein Accession ft: NP_003309
Signal sequence : none found
Transmembrane domains : none found
Protein Kinase Domain: 510-775
Cellular Localization: cytoplasmic and nuclear
60
120
Figure imgf000887_0001
180
EEEKKNLSAS TVLTAQESFS GSLGHLQNRN NSCDSRGQTT KARFLYGENM PPQDAEIβYR 240
NSLRQTNKTK QSCPFGRVPV NLLNSPDCDV KTDDSWPCF MKRQTSRSEC RDLWPGSKP 300
SGNDSCELRN LKSVQNSHFK EPLVSDEKSS ELIITDSITL KNKTESSLLA KLEETKEYQE 360
PEVPESNQKQ WQAKRKSECI NQNPAASSNH WQIPELARKV NTEQKHTTFE QPVFSVSKQS 420
PPISTSKWFD PKSICKTPSS NTLDDYMSCF RTPWKNDFP PACQLSTPYG QPACFQQQQH 480
QILATPLQNL QVLASSSANE CISVKGRIYS ILKQIGSGGS SKVFQVLNEK KQIYAIKYVN 540
LEEADNQTLD SYRNEIAYLN KLQQHSDKII RLYDYEITDQ YIYMVMECGN IDLNSWLKKK 600
KSIDPWERKS YWKNMLEAVH TIHQHGIVHS DLKPANFLIV DGMLKLIDFβ IANQMQPDTT 660
SWKDSQVGT VNYMPPEAIK DMSSSRENGK SKSKISPKSD VWSLGCILYY MTYGKTPFQQ 720
IINQISKLHA IIDPNHEIEF PDIPEKDLQD VLKCCLKRDP KQRISIPELL AHPYVQIQTH 780
PVNQMAKGTT EEMKYVLGQL VGLNSPNSIL KAAKTLYEHY SβGESHNSSS SKTFEKKRGK 840 K
OVARIAN
All6 DNA SEQUENCE
Gene name: G protein-coupled receptor 39 Unigene number: HS.85339 Probeset Accession ft: AA349893 Nucleic Acid Accession #: NM_001508 Coding sequence : 1-1362 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 1 1 1 1 | 1 | 1 | 1 | 1 ATGGCTTCAC CCAGCCTCCC GGGCAGTGAC TGCTCCCAAA TCATTGATCA CAGTCATGTC 60
CCCGAGTTTG AGGTGGCCAC CTGGATCAAA ATCACCCTTA TTCTGGTGTA CCTGATCATC 120
TTCGTGATGG GCCTTCTβββ GAACAGCGCC ACCATTCβGG TCACCCAGβT GCTGCAGAAG 180
AAAGGATACT TβCAβAAGGA GβTβACAβAC CACATGβTβA GTTTGGCTTG CTCGGACATC 240
TTGβTGTTCC TCATCGβCAT GCCCATGGAβ TTCTACAGCA TCATCTGβAA TCCCCTGACC 300
ACGTCCAGCT ACACCCTGTC CTGCAAGCTG CACACTTTCC TCTTCGAGGC CTGCAGCTAC 360 βCTACGCTGC TGCACGTGCT GACACTCAGC TTTGAGCGCT ACATCβCCAT CTGTCACCCC 420
TTCAGGTACA AGβCTβTGTC GGGACCTTGC CAGGTGAAGC TGCTGATTGβ CTTCGTCTGG 480
GTCACCTCCG CCCTGβTββC ACTGCCCTTG CTGTTTGCCA TGGGTACTGA GTACCCCCTG 540
GTGAACGTβC CCAGCCACCG GGGTCTCACT TGCAACCGCT CCAGCACCCG CCACCACβAG 600
CAGCCCGAGA CCTCCAATAT GTCCATCTGT ACCAACCTCT CCAGCCβCTG GACCGTGTTC 660
CAGTCCAGCA TCTTCGβCGC CTTCGTGGTC TACCTCβTββ TCCTGCTCTC CGTAGCCTTC 720
ATGTGCTGGA ACATβATGCA GGTGCTCATβ AAAAβCCAGA AGGGCTCGCT GGCCGGGGGC 780
ACGCGGCCTC CGCAGCTGAG GAAGTCCGAβ AGCGAAβAβA GCAGGACCGC CAGGAGGCAG 840
ACCATCATCT TCCTGAGGCT GATTGTTβTβ ACATTGGCCG TATGCTGGAT GCCCAACCAG 900
ATTCGGAGGA TCATGGCTGC GβCCAAACCC AAGCACGACT ββACβAGGTC CTACTTCCGG 960
GCGTACATGA TCCTCCTCCC CTTCTCGGAG ACGTTTTTCT ACCTCAGCTC GβTCATCAAC 1020
CCGCTCCTGT ACACGβTGTC CTCGCAGCAG TTTCGGCββG TGTTCGTGCA GGTGCTGTGC 1080
TGCCGCCTβT CGCTGCAGCA CGCCAACCAC GAGAAGCGCC TβCβCβTACA TβCβCACTCC 1140
ACCACCGACA GCGCCCGCTT TGTGCAGCGC CCGTTGCTCT TCGCGTCCCG GCβCCAGTCC 1200
TCTGCAAGGA GAACTGAGAA GATTTTCTTA AGCACTTTTC AGAGCGAGGC CβAGCCCCAG 1260
TCTAAGTCCC AGTCATTGAG TCTCGAGTCA CTAGAGCCCA ACTCAGGCGC GAAACCAGCC 1320
AATTCTGCTG CAGAGAATββ TTTTCAGGAβ CATGAAGTTT GA
A117 Protein sequence
Gene name : G protein-coupled receptor 39 Unigene number: Hs.85339 Probeset Accession #: AA349893 Protein Accession # : NM_001508, NP_001409 Signal sequence : none found Pfam domains: 7tm_l [72-172, 224-344] Transmembrane domains: 32-54, 68-90, 111-133, 151-173, 221-243, Cellular Localization: plasma membrane
1 11 21 31 41 51
I I I I I I
MASPSLPGSD CSQIIDHSHV PEFEVATWIK ITLILVYLII FVMGLLGNSA TIRVTQVLQK KGYLQKEVTD HMVSLACSDI LVFLIGMPME FYSIIWNPLT TSSYTLSCKL HTFLFEACSY 120 ATLLHVLTLS FERYIAICHP FRYKAVSGPC QVKLLIGFVW VTSALVALPL LFAMGTEYPL 180 VNVPSHRβLT CNRSSTRHHE QPETSNMSIC TNLSSRWTVF QSSIFGAFW YLWLLSVAF 240 MCWNMMQVLM KSQKGSLAGG TRPPQLRKSE SEESRTARRQ TIIFLRLIW TLAVCWMPNQ 300 IRRIMAAAKP KHDWTRSYFR AYMILLPFSE TFFYLSSVIN PLLYTVSSQQ FRRVFVQVLC 360 CRLSLQHANH EKRLRVHAHS TTDSARFVQR PLLFASRRQS SARRTEKIFL STFQSEAEPQ 420 SKSQSLSLES LEPNSGAKPA NSAAENGFQE HEV
A118 DNA sequence Gene name: bone morphogenetic protein receptor IB (ALK-6) Unigene number: Hs.87223 Probeset Accession tf: AA250737 Nucleic Acid Accession #: NM_001203 Coding sequence: 274-1782 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I
CGCGGGGCGC G IGAGTCGGCG GGGCCTCGCG G IGACGCGGGC A IGTGCGGAGA CCGCGGCGCT 60
GAGGACGCGβ GAGCCGGGAG CGCACGCGCG GβGTβGAGTT CAGCCTACTC TTTCTTAGAT 120
GTGAAAGGAA AGGAAGATCA TTTCATβCCT TβTTβATAAA GGTTCAGACT TCTGCTGATT 180
CATAACCATT TGGCTCTGAG CTATβACAAG AβAGGAAACA AAAAβTTAAA CTTACAAGCC 240
TGCCATAAGT GAGAAGCAAA CTTCCTTGAT AACATCCTTT TGCGAAGTGC AGGAAAATTA 300
AATGTβeβCA CCAAGAAAGA GGATGβTβAG AGTACAGCCC CCACCCCCCG TCCAAAGGTC 360
TTGCGTTβTA AATGCCACCA CCATTGTCCA GAAGACTCAG TCAACAATAT TTGCAGCACA 420
GACGGATATT GTTTCACGAT GATAGAAGAG GATGACTCTβ GGTTGCCTGT GGTCACTTCT 480
GGTTGCCTAG GACTAGAAGG CTCAGATTTT CAGTβTCGGG ACACTCCCAT TCCTCATCAA 540
AGAAGATCAA TTGAATGCTG CACAGAAAGG AACGAATGTA ATAAAGACCT ACACCCTACA 600
CTGCCTCCAT TGAAAAACAG AGATTTTGTT GATGGACCTA TACACCACAG GGCTTTACTT 660
ATATCTGTGA CTGTCTβTAG TTTGCTCTTG GTCCTTATCA TATTATTTTG TTACTTCCGG 720
TATAAAAGAC AAGAAACCAβ ACCTCGATAC AGCATTGGGT TAGAACAGGA TGAAACTTAC 780
ATTCCTCCTG GAGAATCCCT GAGAGACTTA ATTGAGCAGT CTCAGAGCTC AGGAAGTGGA 840
TCAGGCCTCC CTCTGCTGGT CCAAACβACT ATAGCTAAGC AGATTCAGAT GGT6AAACAG 900
ATTGβAAAAG GTCGCTATβG GGAAGTTTGG ATGGGAAAGT GGCGTGGCGA AAAββTAGCT 960
GTGAAAGTGT TCTTCACCAC AGAGGAAβCC AGCTGGTTCA GAGAGACAGA AATATATCAG 1020
ACAGTGTTGA TGAGGCATβA AAACATTTTG GβTTTCATTβ CTGCAGATAT CAAAGGGACA 1080
GGGTCCTβGA CCCAGTTGTA CCTAATCACA βACTATCATβ AAAATGGTTC CCTTTATGAT 1140
TATCTGAAGT CCACCACCCT AGACGCTAAA TCAATGCTGA AGTTAGCCTA CTCTTCTGTC 1200
AGTGGCTTAT GTCATTTACA CACAGAAATC TTTAGTACTC AAGGCAAACC AGCAATTGCC 1260
CATCGAGATC TGAAAAGTAA AAACATTCTG GTGAAGAAAA ATGGAACTTG CTβTATTβCT 1320
GACCTGβGCC TGGCTGTTAA ATTTATTAβT GATACAAATG AAGTTGACAT ACCACCTAAC 1380
ACTCGAGTTβ GCACCAAACG CTATATβCCT CCAGAAGTGT TGGACGAGAG CTTβAACAGA 1440
AATCACTTCC AGTCTTACAT CATGGCTGAC ATGTATAGTT TTGGCCTCAT CCTTTGGGAG 1500
GTTGCTAGβA GATGTGTATC AGGAGGTATA GTGGAAGAAT ACCAGCTTCC TTATCATGAC 1560
CTAGTGCCCA GTGACCCCTC TTATGAGGAC ATGAGGGAGA TTGTβTβCAT CAAGAAGTTA 1620
CGCCCCTCAT TCCCAAACCβ GTGGAβCAβT GATGAGTGTC TAAGGCAGAT GGGAAAACTC 1680
ATGACAGAAT GCTGGGCTCA CAATCCTGCA TCAAGβCTGA CAGCCCTGCG GGTTAAGAAA 1740
ACACTTGCCA AAATGTCAGA GTCCCAGβAC ATTAAACTCT GATAGGAGAG GAAAAGTAAG 1800
CATCTCTGCA GAAAGCCAAC AGGTACTCTT CTGTTTGTGβ GCAGAGCAAA AGACATCAAA 1860
TAAGCATCCA CAGTACAAGC CTTGAACATC GTCCTGCTTC CCAGTGGGTT CAβACCTCAC 1920
CTTTCAGGGA GCGACCTGββ CAAAGACAGA GAAGCTCCCA GAAGGAGAGA TTGATCCβTG 1980
TCTGTTTGTA GGCGGAGAAA CCGTTGGGTA ACTTGTTCAA GATATGATGC AT
A119 Protein sequence Gene name : bone morphogenetic protein receptor IB (ALK-6) Unigene number: Hs.72472 / Hs.87223 Probeset Accession ft: AA250737 / U89326 Protein Accession ft: NP_001194 Signal sequence: 1-13 Transmembrane domains: 128-144 PFAM domains: activin_receptor [30-111] , protein kinase [204-491] Cellular Localization: plasma membrane
1 11 21 31 41 51 l l ll ll ll ll | 1 MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED 60
DSβLPWTSβ CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD 120
GPIHHRALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPβESLRDLI 180
EQSQSSβSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS 240
WFRETEIYQT VLMRHENILG FIAADIKGTG SWTQLYLITD YHENGSLYDY LKSTTLDAKS 300
MLKLAYSSVS βLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360
TNEVDIPPNT RVGTKRYMPP EVLDESLNRN HFQSYIMADM YSFGLILWEV ARRCVSGGIV 420
EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMGKLM TECWAHNPAS 480
RLTALRVKKT LAKMSESQDI KD
A120 DNA SEQUENCE
Gene name: LIV-1 protein, estrogen regulated
Unigene number: Hs.79136
Probeset Accession #: U41060
Nucleic Acid Accession ft: NM_012319.2
Coding sequence: 138-2405 (underlined sequences correspond to start and stop codons)
51 I I 1 I I 1
CTCGTGCCGA ATTCGGCACG AGACCGCGTG TTCGCGCCTG GTAGAGATTT CTCGAAGACA 60
CCAGTGGGCC CGTGTGGAAC CAAACCTGCG CGCGTGGCCG GβCCβTβGGA CAACGAGGCC 120
GCGGAGACGA AGGCGCAATG GCβAβGAAGT TATCTGTAAT CTTGATCCTG ACCTTTGCCC 180
TCTCTGTCAC AAATCCCCTT CATGAACTAA AAGCAGCTGC TTTCCCCCAG ACCACTGAβA 240
AAATTAGTCC GAATTGGGAA TCTCβCATTA ATGTTGACTT GGCAATTTCC ACACGGCAAT 300
ATCATCTACA ACAGCTTTTC TACCGCTATG GAGAAAATAA TTCTTTGTCA GTTGAAGββT 360
TCAβAAAATT ACTTCAAAAT ATAGGCATAG ATAAGATTAA AAGAATCCAT ATACACCATG 420
ACCACGACCA TCACTCAGAC CACβAβCATC ACTCAβACCA TGAGCGTCAC TCAGACCATG 480
AGCATCACTC AGACCACGAG CATCACTCTG ACCATGATCA TCACTCTCAC CATAATCATG 540
CTGCTTCTGG TAAAAATAAG CGAAAAGCTC TTTGCCCAGA CCATGACTCA GATAGTTCAG 600
GTAAAGATCC TAGAAACAGC CAGβββAAAG GAβCTCACCG ACCAGAACAT GCCAGTGGTA 660
GAAGGAATGT CAAGGACAGT GTTAGTβCTA GTGAAGTGAC CTCAACTGTG TACAACACTG 720
TCTCTGAAGG AACTCACTTT CTAβAGACAA TAGAβACTCC AAGACCTGGA AAACTCTTCC 780
CCAAAGATGT AAGCAGCTCC ACTCCACCCA βTGTCACATC AAAGAGCCGG GTGAGCCGGC 840
TGGCTGGTAG GAAAACAAAT GAATCTβTβA GTGAGCCCCG AAAAGGCTTT ATGTATTCCA 900
GAAACACAAA TGAAAATCCT CAGβAGTGTT TCAATGCATC AAAGCTACTβ ACATCTCATG 960
GCATGGβCAT CCAGGTTCCG CTGAATGCAA CAGAGTTCAA CTATCTCTGT CCAGCCATCA 1020
TCAACCAAAT TGATGCTAGA TCTTGTCTGA TTCATACAAG TGAAAAGAAG GCTGAAATCC 1080
CTCCAAAGAC CTATTCATTA CAAATAGCCT GGβTTGGTGG TTTTATAGCC ATTTCCATCA 1140
TCAGTTTCCT GTCTCTGCTG GβββTTATCT TAGTGCCTCT CATGAATCGG GTGTTTTTCA 1200
AATTTCTCCT GAGTTTCCTT GTGGCACTGG CCGTTGGGAC TTTGAGTGGT GATGCTTTTT 1260
TACACCTTCT TCCACATTCT CATGCAAGTC ACCACCATAG TCATAβCCAT GAAGAACCAG 1320
CAATGGAAAT GAAAAGAGGA CCACTTTTCA GTCATCTGTC TTCTCAAAAC ATAGAAGAAA 1380
GTGCCTATTT TGATTCCACG TGGAAGGβTC TAACAGCTCT AGGAGGCCTG TATTTCATGT 1440
TTCTTGTTGA ACATGTCCTC ACATTGATCA AACAATTTAA AβATAAGAAG AAAAAGAATC 1500
AGAAGAAACC TGAAAATGAT GATGATGTGG AGATTAAGAA GCAGTTGTCC AAGTATGAAT 1560
CTCAACTTTC AACAAATGAG GAGAAAGTAG ATACAGATβA TCGAACTGAA GGCTATTTAC 1620
GAβCAGACTC ACAAGAGCCC TCCCACTTTG ATTCTCAGCA CCCTGCAGTC TTGGAAβAAG 1680
AAGAGGTCAT GATAGCTCAT GCTCATCCAC AGGAAGTCTA CAATGAATAT GTACCCAGAG 1740
GGTGCAAGAA TAAATGCCAT TCACATTTCC ACGATACACT CGGCCAGTCA GACGATCTCA 1800
TTCACCACCA TCATGACTAC CATCATATTC TCCATCATCA CCACCACCAA AACCACCATC 1860
CTCACAGTCA CAGCCAGCGC TACTCTCGGG AββAβCTGAA AGATGCCGGC GTCGCCACTT 1920
TGGCCTGGAT GGTGATAATG GGTGATββCC TGCACAATTT CAGCGATGGC CTAGCAATTG 1980 βTβCTGCTTT TACTGAAGGC TTATCAAGTβ GTTTAAGTAC TTCTGTTGCT GTGTTCTGTC 2040
ATβAGTTGCC TCATGAATTA GGTβACTTTβ CTGTTCTACT AAAGGCTGGC ATGACCβTTA 2100
AβCAGGCTβT CCTTTATAAT βCATTβTCAG CCATGCTGGC GTATCTTGGA ATGGCAACAβ 2160
GAATTTTCAT TGGTCATTAT GCTGAAAATG TTTCTATGTG GATATTTGCA CTTACTβCTG 2220
GCTTATTCAT GTATGTTGCT CTGGTTGATA TGβTACCTGA AATGCTGCAC AATGATGCTA 2280
GTGACCATGβ ATβTAβCCGC TGGGGGTATT TCTTTTTACA GAATGCTβββ ATGCTTTTGG 2340
GTTTTGGAAT TATβTTACTT ATTTCCATAT TTβAACATAA AATCGTGTTT CGTATAAATT 2400
TCTAGTTAAG GTTTAAATGC TAGAGTAGCT TAAAAAGTTG TCATAGTTTC AGTAGGTCAT 2460
AGGGAGATGA GTTTGTATGC TGTACTATGC AGCGTTTAAA GTTAGTGGGT TTTGTGATTT 2520
TTGTATTGAA TATTGCTGTC TGTTACAAAG TCAβTTAAAG GTACGTTTTA ATATTTAA6T 2580
TATTCTATCT TGGAGATAAA ATCTGTATGT GCAATTCACC GGTATTACCA GTTTATTATG 2640
TAAACAAGAG ATTTGGCATG ACATGTTCTβ TATβTTTCAG GGAAAAATGT CTTTAATβCT 2700
TTTTCAAGAA CTAACACAGT TATTCCTATA CTGGATTTTA GGTCTCTGAA GAACTGCTββ 2760
TGTTTAGGAA TAAGAATGTG CATGAAβCCT AAAATACCAA βAAAGCTTAT ACTGAATTTA 2820
AGCAAAGAAA TAAAβGAGAA AAGAGAAβAA TCTGAGAATT GGGGAGGCAT AGATTCTTAT 2880
AAAAATCACA AAATTTGTTG TAAATTAGAG βββAGAAATT TAβAATTAAG TATAAAAAββ 2940
CAGAATTAGT ATAGAGTACA TTCATTAAAC ATTTTTGTCA ββATTATTTC CCGTAAAAAC 3000
GTAGTGAGCA CTCTCATATA CTAATTAGTβ TACATTTAAC TTTGTATAAT ACAGAAATCT 3060
AAATATATTT AATGAATTCA AGCAATATAC ACTTGACCAA GAAATTGGAA TTTCAAAATG 3120
TTCGTGCGβG TTATATACCA GATGAβTACA GTGAGTAβTT TATGTATCAC CAGACTGGGT 3180
TATTGCCAAG TTATATATCA CCAAAAGCTG TATGACTβGA TGTTCTGGTT ACCTGGTTTA 3240
CAAAATTATC AGAGTAGTAA AACTTTGATA TATATGAGGA TATTAAAACT ACACTAAGTA 3300
TCATTTβATT CGATTCAGAA AGTACTTTGA TATCTCTCAG TGCTTCAGTG CTATCATTGT 3360
GAGCAATTGT CTTTATATAC GGTACTGTAG CCATACTAGG CCTGTCTGTG GCATTCTCTA 3420
GATGTTTCTT TTTTACACAA TAAATTCCTT ATATCAGCTT G
A121 PROTEIN SEQUENCE Gene name: Liv-l protein, estrogen regulated Unigene number: Hs.79136 Protein Accession ft: NP_036451 Signal sequence: 1-21 Pfam domain: Zip [591-743] Transmembrane domains: 330-346, 352-368, 427-444 , 663-679, 688-703, 730-745 Cellular Localization: plasma membrane
11 21 31 41 51
I I I I I
MARKLSVILI LTFALSVTNP LHELKAAAFP QTTEKISPNW ESGINVDLAI STRQYHLQQL 60 FYRYGENNSL SVEGFRKLLQ NIGIDKIKRI HIHHDHDHHS DHEHHSDHER HSDHEHHSDH 120 EHHSDHDHHS HHNHAASGKN KRKALCPDHD SDSΞGKDPRN SQβKβAHRPE HASGRRNVKD 180 SVSASEVTST VYNTVSEGTH FLETIETPRP βKLFPKDVSS STPPSVTSKS RVSRLAGRKT 240 NESVSEPRKG FMYSRNTNEN PQECFNASKL LTSHGMGIQV PLNATEFNYL CPAIINQIDA 300 RSCLIHTSEK KAEIPPKTYS LQIAWVGGFI AISIISFLSL LGVILVPLMN RVFFKFLLSF 360 LVALAV6TLS GDAFLHLLPH SHASHHHSHS HEEPAMEMKR βPLFSHLSSQ NIEESAYFDS 420 TWKGLTALGG LYFMFLVEHV LTLIKQFKDK KKKNQKKPEN DDDVEIKKQL SKYESQLSTN 480 EEKVDTDDRT EGYLRADSQE PSHFDSQQPA VLEEEEVMIA HAHPQEVYNE YVPRGCKNKC 540 HSHFHDTLGQ SDDLIHHHHD YHHILHHHHH QNHHPHSHSQ RYSREELKDA GVATLAWMVI 600 MGDGLHNFSD GLAIGAAFTE βLSSGLSTSV AVFCHELPHE LβDFAVLLKA GMTVKQAVLY 660 NALSAMLAYL GMATGIFIGH YAENVSMWIF ALTAGLFMYV ALVDMVPEML HNDASDHGCS 720 RWGYFFLQNA GMLLGFGIML LISIFEHKIV FRINF
A122 DNA SEQUENCE Gene name: EGF-like-domain; multiple 6 Unigene number: Hs.12844 Probeset Accession ft: N67551 Nucleic Acid Accession ft: NM_015507 Coding sequence: 241-1902 (underlined sequences correspond to start and stop codons)
I 11 21 31 41 51
I I II 11 11 11 11
CCGCAGAGGA GCCTCGβCCA CGCTAGCCAG GGCGCCCCCA βCCCCTCCCC AβGCCGCβAG 60
CGCCCCTGCC βCGGTGCCTG GCCTCCCCTC CCACACTGCA GGGACAGCAC CCGGTAACTG 120
CGAGTGGAGC GβAGGACCCG AGCGGCTGAG GAGAGAGGAG βCGGCGGCTT AGCTGCTACG 180
GGGTCCGGCC ββCβCCCTCC CGAGGGGGGC TCAGGAGGAG βAAGGAGGAC CCGTGCGAGA 240
ATGCCTCTβC CCTCGAGCCT TGCGCTCCCβ CTGCTGCTCT CCTGGGTGβC AGGTGGTTTC 300
GGGAACGCGβ CCAGTGCAAG GCATCACGGG TTGTTAGCAT CGGCACGTCA GCCTGGGGTC 360
TGTCACTATG GAACTAAACT GGCCTGCTGC TACGGCTGGA GAAGAAACAG CAAGGGAGTC 420
TGTβAAGCTA CATGCGAACC TGGATGTAAG TTTGGTGAGT GCGTGGGACC AAACAAATGC 480
AGATGCTTTC CAGβATACAC CGββAAAACC TGCAβTCAAG ATGTGAATGA GTβTGGAATG 540
AAACCCCGGC CATβCCAACA CAβATGTGTG AATACACACG GAAGCTACAA GTGCTTTTGC 600
CTCAGTGGCC ACATGCTCAT GCCAGATGCT ACGTGTGTGA ACTCTAGGAC ATGTGCCATG 660
ATAAACTGTC AGTACAGCTG TGAAGACACA GAAGAAGGGC CACAGTGCCT GTGTCCATCC 720
TCAGGACTCC βCCTββCCCC AAATGGAAGA GACTGTCTAG ATATTGATGA ATGTGCCTCT 780
GGTAAAGTCA TCTGTCCCTA CAATCGAAGA TGTGTGAACA CATTTGGAAG CTACTACTGC 840
AAATGTCAGA TTββTTTCGA ACTGCAATAT ATCAβTGGAC GATATGACTG TATAGATATA 900
AATGAATGTA CTATGGATAG CCATACGTGC AGCCACCATG CCAATTGCTT CAATACCCAA 960
GGGTCCTTCA AGTGTAAATβ CAAβCAGGGA TATAAAGGCA ATGGACTTCG GTGTTCTGCT 1020
ATCCCTGAAA ATTCTGTGAA GGAAGTCCTC AGAGCACCTG GTACCATCAA AGACAGAATC 1080
AAGAAGTTGC TTβCTCACAA AAACAGCATG AAAAAGAAGG CAAAAATTAA AAATGTTACC 1140
CCAGAACCCA CCAβGACTCC TACCCCTAAG βTGAACTTGC AGCCCTTCAA CTATGAAGAG 1200
ATAGTTTCCA GAGGCGGGAA CTCTCATGGA GGTAAAAAAG GGAATGAAGA GAAAATGAAA 1260
GAGGGGCTTG AGGATGAGAA AAGAGAAβAG AAAGCCCTGA AGAATGACAT AGAGGAGCGA 1320
AGCCTGCGAG βAGATGTGTT TTTCCCTAAG GTGAATGAAG CAGGTGAATT CGGCCTGATT 1380
CTGGTCCAAA GGAAAGCGCT AACTTCCAAA CTGGAACATA AAGATTTAAA TATCTCGGTT 1440
GACTβCAGCT TCAATCATGG GATCTGT6AC TGGAAACA6G ATAGAGAAGA TGATTTTβAC 1500
TGGAATCCTG CTGATCGAGA TAATGCTATT GβCTTCTATA TGGCAGTTCC GβCCTTββCA 1560
GGTCACAAGA AAGACATTGG CCGATTGAAA CTTCTCCTAC CTGACCTGCA ACCCCAAAGC 1620
AACTTCTGTT TGCTCTTTGA TTACCGGCTG GCCGGAGACA AAGTCGGGAA ACTTCGAGTG 1680
TTTGTGAAAA ACAGTAACAA TGCCCTGGCA TGGGAGAAGA CCACGAGTGA GGATGAAAAG 1740
TGGAAGACAG GGAAAATTCA GTTGTATCAA GGAACTGATG CTACCAAAAG CATCATTTTT 1800
GAAGCAGAAC GTGGCAAGGG CAAAACCGGC GAAATCGCAG TGGATGGCGT CTTGCTTGTT 1860
TCAGGCTTAT GTCCAGATAG CCTTTTATCT GTGGATGACT GAATGTTACT ATCTTTATAT 1920
TTGACTTTGT ATGTCAGTTC CCTGGTTTTT TTGATATTGC ATCATAGGAC CTCTGGCATT 1980
TTAGAATTAC TAGCTGAAAA ATTGTAATGT ACCAACAGAA ATATTATTGT AAGATGCCTT 2040
TCTTGTATAA GATATGCCAA TATTTGCTTT AAATATCATA TCACTGTATC TTCTCAGTCA 2100
TTTCTGAATC TTTCCACATT ATATTATAAA ATATGβAAAT GTCAGTTTAT CTCCCCTCCT 2160
CAGTATATCT GATTTGTATA AGTAAGTTGA TGAGCTTCTC TCTACAACAT TTCTAGAAAA 2220
TAGAAAAAAA AGCACAGAGA AATGTTTAAC TGTTTβACTC TTATβATACT TCTTGβAAAC 2280
TATGACATCA AAGATAGACT TTTGCCTAAG TGGCTTAGCT GGGTCTTTCA TAβCCAAACT 2340
TβTATATTTA AATTCTTTGT AATAATAATA TCCAAATCAT CAAAAAAAAA AAAAAAAA
A123 Protein sequence :
Gene name : EGF-like-domain,- multiple 6
Unigene number : Hs .12844
Probeset Accession ft : N67551
Protein Accession # : NP_056322 .2
Signal εequence : 1 -21
Transmembrane domains : none found
MAM domain : 402 -546
EGF domain : 80 -259
Cellular Localization : secreted
I 11 21 31 41 51
I 1 I1 11 11 11 11 MPLPWSLALP LLLSWVAGGF GNAASARHHG LLASARQPGV CHYβTKLACC YGWRRNSKβV 60
CEATCEPGCK FGECVGPNKC RCFPGYTGKT CSQDVNECGM KPRPCQHRCV NTHGSYKCFC 120
LSGHMLMPDA TCVNSRTCAM INCQYSCEDT EEGPQCLCPS SGLRLAPNGR DCLDIDECAS 180
GKVICPYNRR CVNTFGSYYC KCHIGFELQY ISGRYDCIDI NECTMDSHTC SHHANCFNTQ 240
GSFKCKCKQG YKGNGLRCSA IPENSVKEVL RAPGTIKDRI KKLLAHKNSM KKKAKIKNVT 300
PEPTRTPTPK VNLQPFNYEE IVSRGGNSHG GKKGNEEKMK EGLEDEKREE KALKNDIEER 360
SLRGDVFFPK VNEAβEFGLI LVQRKALTSK LEHKDLNISV DCSFNHGICD WKQDREDDFD 420
WNPADRDNAI GFYMAVPALA GHKKDIGRLK LLLPDLQPQS NFCLLFDYRL AGDKVGKLRV 480
FVKNSNNALA WEKTTSEDEK WKTGKIQLYQ GTDATKSIIF EAERGKGKTG EIAVDGVLLV 540
SGLCPDSLLS VDD A124 DNA SEQUENCE Gene name: bone morphogenetic protein 7 (osteogenic protein 1) (BMP7) Unigene number: Hs.170195 Probeset Accession ft: BE616633 Nucleic Acid Accession ft: NM 001719 Coding sequence. 123-1418 (underlined sequences correspond to start and stop codons)
GGGCGCAβCG GGGCCCGTCT GCAGCAAGTG ACCGACCGCC GGGACGβCCβ CCTβCCCCCT 60
CTGCCACCTG GGGCGGTGCG βGCCCGGAGC CCGGAGCGCG GGTAGCGCGT AGAGCCGGCβ 120
CGATGCACβT GCCCTCACTG CGAGCTβCβG CGCCGCACAG CTTCβTββCG CTCTGGGCAC 180
CCCTβTTCCT GCTGCGCTCC GCCCTGGCCG ACTTCAGCCT βGACAACGAβ GTGCACTCGA 240
GCTTCATCCA CCββCGCCTC CGCA6CCAGG AGCGGCGGGA GATGCAGCGC GAβATCCTCT 300
CCATTTTGGG CTTGCCCCAC CGCCCGCGCC CGCACCTCCA GGGCAAGCAC AACTCGGCAC 360
CCATGTTCAT GCTGGACCTG TACAACGCCA TGGCGGTGGA GGAGGGCGGC GGβCCCβGCG 420
GCCAGGGCTT CTCCTACCCC TACAAββCCG TCTTCAGTAC CCAGGGCCCC CCTCTGGCCA 480
GCCTGCAACA TAGCCATTTC CTCACCGACG CCGACATGGT CATGAGCTTC GTCAACCTCβ 540
TGGAACATGA CAAGGAATTC TTCCACCCAC GCTACCACCA TCGAGAGTTC CββTTTβATC 600
TTTCCAAGAT CCCAGAAβGβ GAAβCTGTCA CGGCAGCCGA ATTCCGGATC TACAAGGACT 660
ACATCCβββA ACβCTTCβAC AATGAGACGT TCCGGATCAβ CGTTTATCAβ βTβCTCCAGG 720
AGCACTTGGG CAGGGAATCG GATCTCTTCC TGCTCGACAG CCGTACCCTC TGGGCCTCGG 780
AGGAGGGCTG GCTGGTGTTT GACATCACAG CCACCAGCAA CCACTGGGTG GTCAATCCGC 840
GGCACAACCT GGGCCTGCA6 CTCTCGGTGG AGACGCTGGA TGGβCAβAGC ATCAACCCCA 900
AGTTβGCGββ CCTGATTGβG CGβCACGGGC CCCA6AACAA βCAβCCCTTC ATGGTββCTT 960
TCTTCAAGGC CACGβAGGTC CACTTCCGCA βCATCCCβTC CACGGGGAGC AAACAGCGCA 1020
GCCAGAACCG CTCCAAGACG CCCAAGAACC AββAAGCCCT GCGGATGGCC AACβTββCAβ 1080
AGAACAGCAG CAGCGACCAG AGβCAGGCCT GTAAGAAGCA CGAGCTGTAT GTCAGCTTCC 1140
GAGACCTGGG CTGβCACβAC TGGATCATCβ CGCCTGAAGG CTACβCCβCC TACTACTGTG 1200
AGGGGGAGTG TβCCTTCCCT CTβAACTCCT ACATGAACGC CACCAACCAC GCCATCGTGC 1260
AGACGCTGGT CCACTTCATC AACCCGGAAA CGGTGCCCAA CCCCTGCTGT GCGCCCACβC 1320
AGCTCAATβC CATCTCCGTC CTCTACTTCG ATβACACCTC CAACGTCATC CTGAAGAAAT 1380
ACAGAAACAT ββTβGTCCGG GCCTGTGGCT GCCACTAGCT CCTCCGAGAA TTCAGACCCT 1440
TTGGGGCCAA βTTTTTCTββ ATCCTCCATT GCTCGCCTTG GCCAGGAACC AGCAGACCAA 1500
CTGCCTTTTG TGAGACCTTC CCCTCCCTAT CCCCAACTTT AAAGβTGTGA CAGTATTAGβ 1560
AAACATβAGC AGCATATGGC TTTTGATCAG TTTTTCAGTG GCAGCATCCA ATβAACAAGA 1620
TCCTACAAGC TGTGCAGGCA AAACCTAGCA ββAAAAAAAA ACAACGCATA AAGAAAAATG 1680
GCCGββCCAG GTCATTGGCT GGGAAβTCTC AβCCATGCAC GGACTCGTTT CCAGAGGTAA 1740
TTATGAGCGC CTACCAGCCA GGCCACCCAβ CCGTGGGAGG AAGGGGGCβT GGCAAGGGGT 1800
GGGCACATTG GTGTCTGTGC βAAAβGAAAA TTGACCCGGA AGTTCCTGTA ATAAATGTCA 1860
CAATAAAACG AATGAATG
A125 Protein sequence:
Gene name: bone morphogenetic protein 7 (osteogenic protein 1) (BMP7)
Unigene number: Hs.170195 Probeset Accession ft: BE616633 Protein Accession #: NP_001710.1 Signal sequence: 1-30 Pfam domains: TGFbjpropeptide [37-281] Transmembrane domains: none found Cellular Localization: secreted
1 11 21 31 41 51 1 1 I1 1 | 1 |1 | 1
MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS 60
ILβLPHRPRP HLQβKHNSAP MFMLDLYNAM AVEEGGGPGG QGFSYPYKAV FSTQGPPLAS 120
LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEGEAVT AAEFRIYKDY 180
IRERFDNETF RISVYQVLQE HLGRESDLFL LDSRTLWASE EGWLVFDITA TSNHWWNPR 240
HNLβLQLSVE TLDGQSINPK LAGLIGRHGP QNKQPFMVAF FKATEVHFRS IRSTGSKQRS 300
QNRSKTPKNQ EALRMANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEβYAAYYCE 360
GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSSNVILKKY 420
RNMWRACGC H
A126 DNA SEQUENCE Gene name: integrin, beta 8 Unigene number: Hs.52620 Probeset Accession ft: AA479726 Nucleic Acid Accession ft: NM_002214 Coding sequence: 680-2990 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
CCCAβAβCCβ CCTCCCCCTG TTGCTGGCAT CCCGAGCTTC CTCCCTTGCC AGCCAGGACG 60
CTGCCGACTT βTCTTTβCCC GCTGCTCCGC AGACβGGGCT GCAAAGCTGC AACTAATGGT 120
GTTGβCCTCC CTβCCCACCT βTGGAAGCAA CTβCGCTGAT TGATGCGCCA CAβACTTTTT 180
TCCCCTCβAC CTCGCCGGCG TACCCTCCCA CAGATCCAGC ATCACCCAGT GAATGTACAT 240
TAGGGTGGTT TCCCCCCCAG CTTCGββCTT TGTTTGGGTT TGATTGTGTT TGGCTCTTCG 300
CTAAGCTGAT TTATGCAGCA GAAGCCCCAC CGGCTGGAGA GAAACAAAAG CTCTTTTCTT 360
TGTCCCGGAG CAββCTβCGG AGCCCTTGCA GAGCCCTCTC TCCAGTCGCC GCCGGGCCCT 420
TGGCCGTCGA AββAGGTGCT TCTCCCGGAG ACCGCGGGAC CCGCCGTGCC GAGCCGββAG 480
GGCCGTAGGβ GCCCTGAGAT GCCGAGCGGT GCCCGGGCCC GCTTACCTβC ACCGCTTβCT 540
CCGAGCCGCG GGGTCCGCCT GCTAGGCCTG CGGAAAACGT CCTAGCGACA CTCGCCCGCG 600
GGCCCCGAGβ TCGCCCGGGA GβCCβAβCCC GCβTCCβGAA GGCAGCCAGG CGGCGGGCβC 660
GGGGCGGGCT GTTTTβCATT ATGTGCGGCT CGGCCCTGGC TTTTTTTACC GCTGCATTTG 720
TCTGCCTGCA AAACGACCGG CGAGGTCCCG CCTCGTTCCT CTGGGCAGCC TGGβTGTTTT 780 CACTTGTTCT TGGACTGGGC CAAGGTGAAβ ACAATAGATG TGCATCTTCA AATGCAGCAT 840
CCTGTGCCAβ GTGCCTTGCG CTGGGTCCAG AATGTGGATG GTβTβTTCAA βAββATTTCA 900
TTTCAGGTGG ATCAAGAAGT GAACGTTGTG ATATTGTTTC CAATTTAATA AGCAAACGCT 960
GCTCAβTTGA TTCAATAGAA TACCCATCTG TGCATGTTAT AATACCCACT GAAAATGAAA 1020
TTAATACCCA GGTGACACCA GGAGAAβTGT CTATCCAGCT GCGTCCAGGA GCCβAAGCTA 1080
ATTTTATGCT GAAAGTTCAT CCTCTGAAGA AATATCCTGT GGATCTTTAT TATCTTGTTG 1140
ATGTCTCAGC ATCAATGCAC AATAATATAG AAAAATTAAA TTCCGTTGGA AACGATTTAT 1200
CTAGAAAAAT GGCATTTTTC TCCCGTβACT TTCGTCTTGβ ATTTGGCTCA TACGTTβATA 1260
AAACAβTTTC ACCATACATT AGCATCCACC CCGAAAGGAT TCATAATCAA TGCAβTGACT 1320
ACAATTTAGA CTGCATGCCT CCCCATGGAT ACATCCATGT GCTGTCTTTG ACAGAGAACA 1380
TCACTGAGTT TGAGAAAGCA 6TTCATAGAC AGAAβATCTC TGGAAACATA GATACACCAG 1440
AAGβAGGTTT TGACGCCATG CTTCAββCAβ CTGTCTGTGA AAGTCATATC GGATGGCGAA 1500
AAGAGGCTAA AAGATTGCTG CTGβTβATβA CAβATCAβAC GTCTCATCTC GCTCTTGATA 1560
GCAAATTGGC AGGCATAGTβ GTGCCCAATG ACGGAAACTG TCATCTGAAA AACAACβTCT 1620
ACβTCAAATC GACAACCATG GAACACCCCT CACTAGβCCA ACTTTCAβAG AAATTAATAG 1680
ACAACAACAT TAATGTCATC TTTGCAGTTC AAGGAAAACA ATTTCATTGG TATAAGGATC 1740
TTCTACCCCT CTTGCCAGGC ACCATTCCTG GTGAAATAGA ATCAAAGβCT GCAAACCTCA 1800
ATAATTTGGT AGTGGAAGCC TATCAGAAGC TCATTTCAGA AGTGAAAGTT CAGGTGGAAA 1860
ACCAGGTACA AGGCATCTAT TTTAACATTA CCGCCATCTG TCCAGATGGG TCCAGAAAβC 1920
CAGGCATGGA AGGATGCAGA AACGTGACβA βCAATGATGA AGTTCTTTTC AATGTAACAβ 1980
TTACAATβAA AAAATGTβAT βTCACACβAG GAAAAAACTA TGCAATAATC AAACCTATTG 2040
GTTTTAATβA AACCGCTAAA ATTCATATAC ACAGAAACTG CAGCTGTCAβ TβTβAββACA 2100
ACAβAββACC TAAAββAAAβ TβTGTAGATG AAACTTTTCT AGATTCCAAβ TβTTTCCAGT 2160
GTβATβAβAA TAAATGTCAT TTTGATGAAG ATCAGTTTTC TTCTGAβAGT TGCAAGTCAC 2220
ACAAGGATCA GCCTGTTTGC AGTGGTCGAG GAGTTTGTβT TTβTβGGAAA TGTTCATGTC 2280
ACAAAATTAA GCTTGGAAAA GTGTATGGAA AATACTGTGA AAAGGATGAC TTTTCTTGTC 2340
CATATCACCA TGGAAATCTG TGTGCTβββC ATGGAGAGTG TGAAGCAGGC AGATGCCAAT 2400
GCTTCAGTGG CTGGGAAGGT GATCβATGCC AGTGCCCTTC AGCAGCAβCC CAβCACTGTG 2460
TCAATTCAAA GGGCCAAGTG TGCAGTGGAA GAGGCACGTβ TβTβTGTGGA AGGTGTβAβT 2520
GCACCGATCC CAGGAGCATC GGCCGCTTCT βTGAACACTβ CCCCACCTGT TATACAGCCT 2580 βCAAβGAAAA CTGGAATTGT ATGCAATGCC TTCACCCTCA CAATTTGTCT CAGGCTATAC 2640
TTGATCAGTG CAAAACCTCA TGTGCTCTCA TGGAACAACA GCATTATGTC GACCAAACTT 2700
CAβAATGTTT CTCCAGCCCA AGCTACTTβA GAATATTTTT CATCATTTTC ATAGTTACAT 2760
TCTTβATTGG GTTGCTTAAA GTCCTβATCA TTAGACAGGT GATACTACAA TGGAATAβTA 2820
ATAAAATTAA GTCCTCATCA GATTACAβAG TGTCAGCCTC AAAAAAGGAT AAGTTGATTC 2880
TGCAAAβTGT TTGCACAAGA GCAβTCACCT ACCGACGTGA GAAGCCTβAA GAAATAAAAA 2940
TGβATATCAβ CAAATTAAAT GCTCATGAAA CTTTCAGGTG CAACTTCTAA AAAAAGATTT 3000
TTAAACACTT AATGGGAAAC TGGAATTGTT AATAATTGCT CCTAAAGATT ATAATTTTAA 3060
AAGTCACAGG AGGAGACAAA TTGCTCACGβ TCATGCCAGT TβCTGGTTGT ACACTCGAAC 3120
GAAGACTGAC AAGTATCCTC ATCATGATGT βACTCACATA βCTGCTGACT TTTTCAGAGA 3180
AAAATGTGTC TTACTACTGT TTGAGACTAG TGTCGTTβTA GCACTTTACT GTAATATATA 3240
ACTTATTTAG ATCAGCATAG AATGTAGATC CTCTGAAGAβ CACTGATTAC ACTTTACAGG 3300
TACCTGTTAT CCCTACGCTT CCCAGAGAGA ACAATGCTGT βAβAβAGTTT AGCATTGTGT 3360
CACTACAAGG GTACAGTAAT CCCTGCACTG GACATGTGAG GAAAAAAATA ATCTGGCAAG 3420
TATATTCTAA GGTTGCCAAA CACTTCAACA GTTGGTGβTT GAATAβACAA GAACAGCTAG 3480
ATGAATAAAT GATTCGTGTT TCACTCTTTC AAGAGβTβAA CAβATACAAC CTTAATCTTA 3540
AAAβATTATT GCTTTTTAAA GTGTGTAGTT TTATβCATβT GTGTTTATGG TTTGCTTATT 3600
TTTGCAAGAT GGATACTAAT TCCAGCATTC TCTCCTCTTT βCCTTTATGT TTTGTTTTCT 3660
TTTTTACAGG ATAAβTTTAT GTATGTCACA GATβACTββA TTAATTAAGT GCTAAGTTAC 3720
TACTβCCATA AAAAACTAAT AATACAATGT CACTTTATCA GAATACTAGT TTTAAAAGCT 3780 GAATGTTAA
A127 Protein sequence :
Gene name : Integrin, beta 8
Unigene number: Hs .52620
Probeset Accession ft : AA479726
Protein Accession ft : NP_002205. 1
Signal sequence : 1-39
Transmembrane domains : 682-704
EGF domain : 552-584
INB domain: 54-469
Cellular Localization : plasma membrane
1 11 21 31 41 51
I I I I I I
MCGSALAFFT AAFVCLQNDR RGPASFLWAA WVFSLVLGLG QGEDNRCASS NAASCARCLA 60
LGPECGWCVQ EDFISGGSRS ERCDIVSNLI SKGCSVDSIE YPSVHVIIPT ENEINTQVTP 120
GEVSIQLRPβ AEANFMLKVH PLKKYPVDLY YLVDVSASMH NNIEKLNSVG NDLSRKMAFF 180
SRDFRLGFβS YVDKTVSPYI SIHPERIHNQ CSDYNLDCMP PHGYIHVLSL TENITEFEKA 240
VHRQKISGNI DTPEGGFDAM LQAAVCESHI GWRKEAKRLL LVMTDQTSHL ALDSKLAGIV 300
VPNDβNCHLK NNVYVKSTTM EHPSLGQLSE KLIDNNINVI FAVQGKQFHW YKDLLPLLPG 360
TIAGEIESKA ANLNNLWEA YQKLISEVKV QVENQVQβlY FNITAICPDβ SRKPGMEGCR 420
NVTSNDEVLF NVTVTMKKCD VTGGKNYAII KPIGFNETAK IHIHRNCSCQ CEDNRβPKGK 480
CVDETFLDSK CFQCDENKCH FDEDQFSSES CKSHKDQPVC SGRβVCVCβK CSCHKIKLCK 540
VYβKYCEKDD FSCPYHHGNL CAGHGECEAG RCQCFSβWEβ DRCQCPSAAA QHCVNSKGQV 600
CSGRβTCVCG RCECTDPRSI GRFCEHCPTC YTACKENWNC MQCLHPHNLS QAILDQCKTS 660
CALMEQQHYV DQTSECFSSP SYLRIFFIIF IVTFLIGLLK VLIIRQVILQ WNΞNKIKSSS 720 DYRVSASKKD KLILQSVCTR AVTYRREKPE EIKMDISKLN AHETFRCNF
A128 DNA SEQUENCE
Gene name : G protein-coupled receptor 64 Unigene number: Hs.184942 Probeset Accession ft: AA435577 Nucleic Acid Accession ft: NM_005756 Coding sequence: 73-3117 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
AGCCAGCCCG AGGACGCGAO CGGCAβGTGT GCACAβAGGT TCTCCACTTT GTTTTCTGAA 60
CTCGCGGTCA GGATGGTTTT CTCTGTCAGG CAGTβTβGCC ATGTTGGCAG AACTGAAGAA 120
GTTTTACTGA CGTTCAAGAT ATTCCTTGTC ATCATTTGTC TTCATGTCGT TCTGGTAACA 180
TCCCTGGAAG AAGATACTGA TAATTCCAGT TTGTCACCAC CACCTGCTAA ATTATCTGTT 240
GTCAGTTTTG CCCCCTCCTC CAATGAGGTT GAAACAACAA GCCTCAATβA TβTTACTTTA 300
AGCTTACTCC CTTCAAACGA AACAGAAAAA ACTAAAATCA CTATAGTAAA AACCTTCAAT 360
GCTTCAGGCG TCAAACCCCA GAβAAATATC TGCAATTTGT CATCTATTTβ CAATGACTCA 420
GCATTTTTTA GAGGTGAβAT CATβTTTCAA TATGATAAAG AAAGCACTGT TCCCCAGAAT 480 '
CAACATATAA CGAATGGCAC CTTAACTGGA GTCCTGTCTC TAAGTGAATT AAAACGCTCA 540
GAGCTCAACA AAACCCTGCA AACCCTAAGT GAβACTTACT TTATAATβTG TGCTACAGCA 600
GAGβCCCAAA βCACATTAAA TT6TACATTC ACAATAAAAC TGAATAATAC AATGAATβCA 660
TβTGCTGCAA TAGCCGCTTT GβAAAβAGTA AAGATTCGAC CAATGGAACA CTGCTGCTGT 720
TCTGTCAβGA TACCCTGCCC TTCCTCCCCA GAAGAGTTGG GAAAGCTTCA GTGTGACCTG 780
CAGGATCCCA TTGTCTGTCT TGCTGACCAT CCACGTGβCC CACCATTTTC TTCCAβCCAA 840
TCCATCCCAG TGβTβCCTCβ ββCCACTGTG CTTTCCCAGβ TCCCCAAAGC TACCTCTTTT 900
GCTGAGCCTC CAGATTATTC ACCTGTGACC CACAATGTTC CCTCTCCAAT AβββGAGATT 960
CAACCCCTTT CACCCCAGCC TTCAGCTCCC ATAGCTTCCA GCCCTGCCAT TGACATGCCC 1020
CCACAGTCTG AAACβATCTC TTCCCCTATβ CCCCAAACCC ATGTCTCCGβ CACCCCACCT 1080
CCTGTGAAAG CCTCATTTTC CTCTCCCACC GTβTCTGCCC CTGCβAATGT CAACACTACC 1140
AGCβCACCTC CTGTCCAGAC AGACATCGTC AACACCAGCA GTATTTCTGA TCTTGAGAAC 1200
CAAGTGTTGC AGATGβAGAA GGCTCTGTCC TTGβGCAβCC TGGAGCCTAA CCTCGCAGGA 1260
GAAATGATCA ACCAAGTCAG CAGACTCCTT CATTCCCCGC CTGACATβCT ββCCCCTCTG 1320
GCTCAAAβAT TβCTGAAAGT AGTββATGAC ATTGGCCTAC AGCTCAACTT TTCAAACACG 1380
ACTATAAGTC TAACCTCCCC TTCTTTGGCT CTβGCTGTGA TCAGAβTGAA TGCCAGTAGT 1440
TTCAACACAA CTACCTTTGT GβCCCAAGAC CCTGCAAATC TTCAβGTTTC TCTGGAAACC 1500
CAAGCTCCTG AGAACAGTAT TGβCACAATT ACTCTTCCTT CATCβCTGAT GAATAATTTA 1560
CCAGCTCATG ACATGGAGCT AGCTTCCAGG GTTCAGTTCA ATTTTTTTGA AACACCTGCT 1620
TTβTTTCAGG ATCCTTCCCT GGAGAACCTC TCTCTβATCA GCTACGTCAT ATCATCGAGT 1680
GTTGCAAACC TGACCGTCAβ βAACTTβACA AGAAACGTGA CAGTCACATT AAAβCACATC 1740
AACCCGAGCC AGGATGAGTT AACAβTGAGA TGTGTATTTT GGGACTTGGG CAGAAATGGT 1800
GGCAGAGGAG GCTGGTCAGA CAATGGCTGC TCTGTCAAAG ACAβGAGATT GAATGAAACC 1860
ATCTGTACCT GTAGCCATCT AACAAGCTTC GβCβTTCTβC TGGACCTATC TAGβACATCT 1920
GTGCTGCCTG CTCAAATGAT GGCTCTGACG TTCATTACAT ATATTGGTTG TGββCTTTCA 1980
TCAATTTTTC TGTCAGTGAC TCTTGTAACC TACATAGCTT TTGAAAAGAT CCββAGGGAT 2040
TACCCTTCCA AAATCCTCAT CCAGCTGTGT GCTβCTCTβC TTCTGCTGAA CCTGGTCTTC 2100
CTCCTGGACT CGTGGATTGC TCTGTATAAG ATβCAAGGCC TCTGCATCTC AGTββCTGTA 2160
TTTCTTCATT ATTTTCTCTT GGTCTCATTC ACATGGATβG GCCTAGAAGC ATTCCATATG 2220
TACCTGGCCC TTGTCAAAGT ATTTAATACT TACATCCGAA AATACATCCT TAAATTCTGC 2280
ATTGTCGβTT GGGGGGTACC AGCTGTGGTT GTGACCATCA TCCTGACTAT ATCCCCAGAT 2340
AACTATGGGC TTGGATCCTA TGGGAAATTC CCCAATGGTT CACCGGATGA CTTCTGCTGG 2400
ATCAACAACA ATGCAGTATT CTACATTACG GTGGTGGGAT ATTTCTGTGT GATATTTTTG 2460
CTGAACGTCA GCATGTTCAT TGTββTCCTG GTTCAGCTCT GTCGAATTAA AAAGAAGAAG 2520
CAACTGGGAG CCCAGC6AAA AACCAGTATT CAAGACCTCA GGAGTATCGC TGGCCTTACA 2580
TTTTTACTGG GAATAACTTG GGGCTTTGCC TTCTTTCCCT GGGGACCAGT TAACβTGACC 2640
TTCATGTATC TGTTTGCCAT CTTTAATACC TTACAAGGAT TTTTCATATT CATCTTTTAC 2700
TGTGTGGCCA AAGAAAATGT CAGβAAGCAA TGGAGGCGGT ATCTTTGTTG TGβAAAGTTA 2760
CGGCTGGCTG AAAATTCTGA CTGGAGTAAA ACTGCTACTA ATGGTTTAAA GAAGCAGACT 2820
GTAAACCAAG GAGTGTCCAG CTCTTCAAAT TCCTTACAGT CAAGCAGTAA CTCCACTAAC 2880
TCCACCACAC TGCTAGTGAA TAATGATTGC TCAGTACACG CAAGCβGGAA TGGAAATGCT 2940
TCTACAβAβA GGAATGGGGT CTCTTTTAGT GTTCAGAATG GAβATGTGTG CCTTCACGAT 3000
TTCACTGGAA AACAGCACAT GTTTAACGAG AAGGAAGATT CCTGCAATGG GAAAGβCCGT 3060
ATGGCTCTCA GAAGGACTTC AAAGCGGGGA AGCTTACACT TTATTβAGCA AATGTGATTC 3120
CTTTCTTCTA AAATCAAAGC ATGATGCTTG ACAβTβTGAA ATGTCCAATT TTACCTTTTA 3180
CACAATβTGA GATGTATGAA AATCAACTCA TTTTATTCTC GGCAACATCT GGAβAAβCAT 3240
AAβCTAATTA AGGGCGATGA TTATTATTAC AAGAAGAAAC CAAGACATTA CACCATGGTT 3300
TTTAGACATT TCTGATTTGG TTTCTTATCT TTCATTTTAT AAGAAGGTTG GTTTTAAACA 3360
ATACACTAAG AATGACTCCT ATAAAGAAAA CAAAAAAAGG TAGTGAACTT TCAGCTACCT 3420
TTTAAAGAGG CTAAGTTATC TTTGATAACA TCATATAAAG CAACTGTTGA CTTCAGCCTG 3480
TTGGTGAGTT TAGTTGTGCA TGCCTTTGTT GTATATAAGC TAAATTCTAG TGACCCATGT 3540
GTCAAAAATC TTACTTCTAC ATTTTTTTGT ATTTATTTTC TACTGTGTAA ATGTATTCCT 3600
TTGTAGAATC ATGGTTGTTT TGTCTCACGT GATAATTCAG AAAATCCTTG CTCGTTCCGC 3660
AAATCCTAAA GCTCCTTTTG GAβATGATAT AGGATGTGAA ATACAGAAAC CTCAGTGAAA 3720
TCAAGAAATA ATGATCCCAG CCAGACTGAG AAAATGTAAG CAGACAβTβC CACAGTTAGC 3780
TCATACAGTG CCTTTGAGCA AGTTAGGAAA AGATβCCCCC ACTGGGCAGA CACAGCCCTA 3840
TGGGTCATββ TTTβACAAAC AβAGTGAGAG ACCATATTTT AGCCCCACTC ACCCTCTTGG 3900 βTβCACGACC TGTACAGCCA AACACAGCAT CCAATATGAA TACCCATCCC CTβACCGCAT 3960
CCCCAGTAGT CAGATTATAG AATCTGCACC AAGATGTTTA βCTTTATACC TTGGCCACAβ 4020
AGAGGGATGA ACTGTCATCC AβACCATGTG TCAGGAAAAT TGTGAACGTA GATβAβGTAC 4080
ATACACTGCC GCTTCTCAAA TCCCCAGAGC CTTTAGGAAC AGGAGAGTAG ACTAββATTC 4140
CTTCTCTTAA AAAGGTACAT ATATATGGAA AAAAATCATA TTGCCGTTCT TTAAAAGGCA 4200
ACTGCATGGT ACATTGTTGA TTGTTATGAC TGGTACACTC TGGCCCAGCC AβAβCTATAA 4260
TTGTTTTTTA AATGTβTCTT GAAGAATGCA CAGTGACAAG GGGAGTAGCT ATTGGGAACA 4320
GGGAACTGTC CTACACTGCT ATTGTTGCTA CATGTATCGA GCCTTGATTβ CTCCTAβTTA 4380
TATACAβGGT CTATCTTGCT TCCTACCTAC ATCTGCTTGA GCAGTGCCTC AAβTACATCC 4440
TTATTAGβAA CATTTCAAAC CCCTTTTAGT TAAGTCTTTC ACTAAGβTTC TCTTGCATAT 4500
ATTTCAAGTG AATGTTGGAT CTCAGACTAA CCATAGTAAT AATACACATT TCTGTGAGTG 4560 CTGACTTGTC TTTGCAATAT TTCTTTTCTG ATTTATTTAA TTTTCTTGTA TTTATATGTT AAAATCAAAA ATGTTAAAAT CAATGAAATA AATTTGCAGT TAAGA
A129 Protein sequence Gene name: G protein-coupled receptor 64 Unigene number: Hs.184942 Protein Accession ft : NP_005747.1 Signal sequence : 1-38 GPS domain: 564-615
Transmembrane domains: 624-646, 660-682, 688-710, 733-755, 783-805 , 828-850 , 858-880 Cellular Localization: plasma membrane
60
Figure imgf000894_0001
120
GEIMFQYDKE STVPQNQHIT NGTLTGVLSL SELKRSELNK TLQTLSETYF IMCATAEAQS 180
TLNCTFTIKL NNTMNACAAI AALERVKIRP MEHCCCSVRI PCPSSPEELG KLQCDLQDPI 240
VCLADHPR6P PFSSSQSIPV VPRATVLSQV PKATSFAEPP DYSPVTHNVP SPICEIQPLS 300
PQPSAPIASS PAIDMPPQSE TISSPMPQTH VSGTPPPVKA SFSSPTVSAP ANVNTTSAPP 360
VQTDIVNTSS ISDLENQVLQ MEKALSLGSL EPNLAGEMIN QVSRLLHSPP DMLAPLAQRL 420
LKWDDIGLQ LNFSNTTISL TSPSLALAVI RVNASSFNTT TFVAQDPANL QVSLETQAPE 480
NSIGTITLPS SLMNNLPAHD MELASRVQFN FFETPALFQD PSLENLSLIS YVISSSVANL 540
TVRNLTRNVT VTLKHINPSQ DELTVRCVFW DLGRNGβRGG WSDNGCSVKD RRLNETICTC 600
SHLTSFGVLL DLSRTSVLPA QMMALTFITY IGCGLSSIFL SVTLVTYIAF EKIRRDYPSK 660
ILIQLCAALL LLNLVFLLDS WIALYKMQGL CISVAVFLHY FLLVSFTWMG LEAFHMYLAL 720
VKVFNTYIRK YILKFCIVGW GVPAVWTII LTISPDNYGL GSYGKFPNGS PDDFCWINNN 780
AVFYITWGY FCVIFLLNVS MFIWLVQLC RIKKKKQLβA QRKTSIQDLR SIAGLTFLLG 840
ITWGFAFFAW GPVNVTFMYL FAIFNTLQGF FIFIFYCVAK ENVRKQWRRY LCCGKLRLAE 900
NSDWSKTATN GLKKQTVNQG VSSSSNSLQS SSNSTNSTTL LVNNDCSVHA SGNβNASTER 960
NGVSFSVQNG DVCLHDFTGK QHMFNEKEDS CNGKGRMALR RTSKRβSLHF IEQM
A130 DNA SEQUENCE βene name: β protein-coupled receptor 49 (GPR49) (HG38) (LGR5)
Unigene number: Hs.285529
Probeset Accession ff: AA460530
Nucleic Acid Accession ft: NM_003667
Coding sequence: 201-2924 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I
GTGGCGGCAA CCGGCACCTC AGTCCCCGCC GCβCTTCTCC TCGCCGCCCA CGCCGTGβGβ 60
TCAGGAACGC GGCGTCTGGC GCTβCAGACG CCCβCTβAGT TGCAGAAGCC CACββAGCGG 120
CGCCCGGCGC GCCACGGCCC GTAGCAGTCC GGTβCTGCTC TCCGCCCGCG TCCGGCTCGT 180
GGCCCCCTAC TTCGGGCACC ATGGACACCT CCCββCTCGG TGTGCTCCTG TCCTTGCCTG 240
TGCTGCTGCA GCTGβCGACC GββGGCACCT CTCCCAGGTC TGGTGTGTTG CTGAGGGβCT 300
GCCCCACACA CTGTCATTGC GAGCCCGACG GCAGGATβTT GCTCAGGGTG GACTGCTCCG 360
ACCTGGGGCT CTCGGAGCTG CCTTCCAACC TCAGCGTCTT CACCTCCTAC CTAGACCTCA 420
GTATGAACAA CATCAGTCAG CTGCTCCCGA ATCCCCTGCC CAGTCTCCGC TTCCTGGAGG 480
AGTTACGTCT TGCGGGAAAC GCTCTGACAT ACATTCCCAA GGGAGCATTC ACTGGCCTTT 540
ACAGTCTTAA AGTTCTTATG CTGCAGAATA ATCAGCTAAG ACACGTACCC ACAGAAGCTC 600
TGCAGAATTT GCGAAGCCTT CAATCCCTGC GTCTGGATGC TAACCACATC AGCTATGTGC 660
CCCCAAGCTG TTTCAGTGGC CTGCATTCCC TGAGGCACCT GTGGCTGGAT GACAATGCGT 720
TAACAGAAAT CCCCGTCCAG GCTTTTAGAA GTTTATCGGC ATTGCAAβCC ATGACCTTGG 780
CCCTGAACAA AATACACCAC ATACCAGACT ATGCCTTTGG AAACCTCTCC AGCTTΘ3TAG 840
TTCTACATCT CCATAACAAT AGAATCCACT CCCTGGGAAA GAAATGCTTT GATGGGCTCC 900
ACAGCCTAGA GACTTTAGAT TTAAATTACA ATAACCTTGA TGAATTCCCC ACTGCAATTA 960
GβACACTCTC CAACCTTAAA GAACTA6GAT TTCATAGCAA CAATATCAGG TCGATACCTG 1020
AGAAAGCATT TGTAGGCAAC CCTTCTCTTA TTACAATACA TTTCTATGAC AATCCCATCC 1080
AATTTGTTGG GAGATCTGCT TTTCAACATT TACCTGAACT AAGAACACTG ACTCTGAATG 1140
GTGCCTCACA AATAACTGAA TTTCCTGATT TAACTGβAAC TGCAAACCTG GAGAGTCTGA 1200
CTTTAACTGG ACCACAGATC TCATCTCTTC CTCAAACCGT CTGCAATCAG TTACCTAATC 1260
TCCAAGTGCT AGATCTGTCT TACAACCTAT TAGAAGATTT ACCCAGTTTT TCAGTCTGCC 1320
AAAAGCTTCA GAAAATTGAC CTAAGACATA ATGAAATCTA CβAAATTAAA GTTGACACTT 1380
TCCAGCAGTT GCTTAGCCTC CβATCGCTGA ATTTGGCTTG GAACAAAATT GCTATTATTC 1440
ACCCCAATGC ATTTTCCACT TTGCCATCCC TAATAAAGCT βGACCTATCG TCCAACCTCC 1500
TGTCGTCTTT TCCTATAACT GGGTTACATG GTTTAACTCA CTTAAAATTA ACAGGAAATC 1560
ATGCCTTACA GAGCTTGATA TCATCTGAAA ACTTTCCAGA ACTCAAGGTT ATAGAAATGC 1620
CTTATGCTTA CCAGTGCTGT GCATTTGGAβ TGTGTGAβAA TGCCTATAAG ATTTCTAATC 1680
AATGGAATAA AGGTGACAAC AGCAβTATGG ACGACCTTCA TAAGAAAGAT GCTGGAATGT 1740
TTCAGGCTCA AGATGAACGT GACCTTβAAG ATTTCCTGCT TGACTTTβAβ GAAGACCTGA 1800
AAGCCCTTCA TTCAGTGCAG TGTTCACCTT CCCCAGGCCC CTTCAAACCC TGTGAACACC 1860
TβCTTβATββ CTGGCTGATC AGAATTGGAG TGTGGACCAT AGCAGTTCTG GCACTTACTT 1920
GTAATGCTTT GGTGACTTCA ACAGTTTTCA GATCCCCTCT GTACATTTCC CCCATTAAAC 1980
TGTTAATTGG GGTCATCGCA GCAGTGAACA TCCTCACGGG AGTCTCCAGT GCCGTβCTGβ 2040
CTGGTGTGGA TGCGTTCACT TTTGGCAGCT TTGCACGACA TGGTGCCTβG TGGGAGAATG 2100
GGβTTGGTTG CCATGTCATT GGTTTTTTGT CCATTTTTGC TTCAGAATCA TCTGTTTTCC 2160
TGCTTACTCT GGCAGCCCTG GAGCGTGGGT TCTCTGTGAA ATATTCTGCA AAATTTβAAA 2220
CGAAAGCTCC ATTTTCTAGC CTGAAAGTAA TCATTTTGCT CTGTGCCCTG CTG6CCTTGA 2280
CCATGGCCGC AGTTCCCCTG CTGGGTGGCA GCAAGTATGβ CGCCTCCCCT CTCTGCCTGC 2340
CTTTGCCTTT TGGGGAGCCC AGCACCATGG GCTACATGGT CGCTCTCATC TTGCTCAATT 2400
CCCTTTGCTT CCTCATGATG ACCATTGCCT ACACCAAGCT CTACT6CAAT TTββACAAGG 2460 GAGACCTCβA GAATATTTGG GACTGCTCTA TGGTAAAACA CATTβCCCTβ TTGCTCTTCA 2520
CCAACTGCAT CCTAAACTGC CCTGTGGCTT TCTTGTCCTT CTCCTCTTTA ATAAACCTTA 2580
CATTTATCAG TCCTGAAGTA ATTAAGTTTA TCCTTCTGGT GGTAGTCCCA CTTCCTGCAT 2640
GTCTCAATCC CCTTCTCTAC ATCTTβTTCA ATCCTCACTT TAAGGAβGAT CTGGTGAGCC 2700
TGAGAAAβCA AACCTACGTC TG6ACAACAT CAAAACACCC AAβCTTβATβ TCAATTAACT 2760
CTGATGATβT CGAAAAACAG TCCTGTGACT CAACTCAAGC CTTCGTAACC TTTACCAGCT 2820
CCAGCATCAC TTATβACCTG CCTCCCAGTT CCGTGCCATC ACCAGCTTAT CCAGTGACTG 2880
AGAGCTGCCA TCTTTCCTCT GTGβCATTTG TCCCATGTCT CTAATTAATA TGTGAAGGAA 2940
AATGTTTTCA AAGGTTGAGA ACCTGAAAAT GTGAβATTGA βTATATCACA GCAGTAATTA 3000
ATAAGAAGAβ CTGAGGTGAA ACTCGGTTTA AA
A131 Protein sequence Gene name : G protein-coupled receptor 49 (GPR49) (HG38) (LGR5) Unigene number: Hs.285529 Protein Accession # : NP_003658.1 Signal sequence : 1-22 Transmembrane domains : 557-579, 596-618, 641-663, 687-709, 724-746, 770-792, 803-825 Cellular Localization: plasma membrane
1 11 21 31 41 51 1 1 | 1 1 1 | 1 | 1 | 1 MDTSRLGVLL SLPVLLQLAT βGSSPRSGVL LRGCPTHCHC EPDβRMLLRV DCSDLβLSEL 60
PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALTYIPKβAF TGLYSLKVLM 120
LQNNQLRHVP TEALQNLRSL QSLRLDANHI SYVPPSCFSG LHSLRHLWLD DNALTEIPVQ 180
AFRSLSALQA MTLALNKIHH IPDYAFGNLS SLWLHLHNN RIHSLGKKCF DGLHSLETLD 240
LNYNNLDEFP TAIRTLSNLK ELGFHSNNIR SIPEKAFVGN PSLITIHFYD NPIQFVGRSA 300
FQHLPELRTL TLNGASQITE FPDLTGTANL ESLTLTGAQI SSLPQTVCNQ LPNLQVLDLS 360
YNLLEDLPSF SVCQKLQKID LRHNEIYEIK VDTFQQLLSL RSLNLAWNKI AIIHPNAFST 420
LPSLIKLDLS SNLLSSFPIT GLHGLTHLKL TGNHALQSLI SSENFPELKV IEMPYAYQCC 480
AFGVCENAYK ISNQWNKGDN SSMDDLHKKD AGMFQAQDER DLEDFLLDFE EDLKALHSVQ 540
CSPSPGPFKP CEHLLDGWLI RIGVWTIAVL ALTCNALVTS TVFRSPLYIS PIKLLIGVIA 600
AVNMLTGVSS AVLAβVDAFT FGSFARHGAW WENGVGCHVI GFLSIFASES SVFLLTLAAL 660
ER6FSVKYSA KFETKAPFSS LKVIILLCAL LALTMAAVPL LββSKYβASP LCLPLPFGEP 720
STMβYMVALI LLNSLCFLMM TIAYTKLYCN LDKGDLENIW DCSMVKHIAL LLFTNCILNC 780
PVAFLSFSSL INLTFISPEV IKFILLVWP LPACLNPLLY ILFNPHFKED LVSLRKQTYV 840
WTRSKHPSLM SINSDDVEKQ SCDSTQALVT FTSSSITYDL PPSSVPSPAY PVTESCHLSS 900
VAFVPCL
A132 DNA SEQUENCE
Gene name: parathyroid hormone receptor 2
Unigene number: Hs.159499
Probeset Accession ft: U25128
Nucleic Acid Accession ft: NM_005048
Coding sequence: 143-1795 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
GGCCGGTGGC CCGGGCCCGA CCACCCCAGC TGCGCGTCβT TACTGGCCAC AAGTTTGCTC 60 TGGGCCAβCC AAGTTGGCAA CTTGGAAGCT TCTCCCGGGC TCTGGAGGAG GGTCCCTGCT 120 TCTTCCTACA GCCβTTCCGG GCATGGCCGG GCTGGGGGCG TCGCTCCACG TCTGβGGTTG 180 GCTAATGCTC GGCAGCTGCC TCCTGGCCAG AGCCCAGCTG GATTCTGATG GCACCATTAC 240 TATAGAGGAG CAGATTGTCC TTGTβCTGAA AβCGAAAβTA CAATGTGAAC TCAACATCAC 300 AGCTCAACTC CAGGAGGGAG AAGβTAATTβ TTTCCCTβAA TβββATβGAC TCATTTGTTG 360 GCCCAGAGGA ACAGTGGGGA AAATATCGGC TGTTCCATGC CCTCCTTATA TTTATGACTT 420 CAACCATAAA GGAGTTGCTT TCCGACACTG TAACCCCAAT GβAACATGGG ATTTTATGCA 480 CAGCTTAAAT AAAACATβGG CCAATTATTC AGACTGCCTT CGCTTTCTGC AβCCAGATAT 540 CAGCATAGGA AAGCAAGAAT TCTTTGAACβ CCTCTATGTA ATGTATACCG TTGGCTACTC 600 CATCTCTTTT GGTTCCTTGG CTGTGGCTAT TCTCATCATT GGTTACTTCA GACGATTGCA 660 TTGCACTAββ AACTATATCC ACATGCACTT ATTTGTGTCT TTCATGCTGA GAGCTACAAG 720 CATCTTTGTC AAAGACAGAβ TAGTCCATGC TCACATAGGA GTAAAGGAGC TGGAGTCCCT 780 AATAATGCAG GATGACCCAC AAAATTCCAT TGAGGCAACT TCTGTGGACA AATCACAATA 840 TATCGGGTGC AAGATTGCTG TTGTGATGTT TATTTACTTC CTGGCTACAA ATTATTATTG 900 GATCCTGGTG GAAGGTCTCT ACCTGCATAA TCTCATCTTT GTGGCTTTCT TTTCGGACAC 960 CAAATACCTG TGGββCTTCA TCTTGATAGG CTGGGGGTTT CCAGCAGCAT TTGTTGCAGC 1020 ATGGGCTGTG GCACGAGCAA CTCTGGCTGA TGCGAGGTGC TGGGAACTTA GTGCTGGAGA 1080 CATCAAGTGG ATTTATCAAG CACCGATCTT AGCAGCTATT GGGCTGAATT TTATTCTGTT 1140 TCTGAATACG GTTAGAGTTC TAGCTACCAA AATCTGGGAG ACCAATGCAG TTGGGCATGA 1200 CACAAGGAAG CAATACAGGA AACTGGCCAA ATCGACACTG GTCCTGGTCC TAGTCTTTGG 1260 AGTβCATTAC ATCGTGTTCG TATGCCTGCC TCACTCCTTC ACTGGGCTCG GGTGGGAGAT 1320 CCGCATGCAC TGTGAGCTCT TCTTCAACTC CTTTCAGGGT TTCTTTGTβT CTATCATCTA 1380 CTGCTACTβC AATGGAGAGβ TTCAGGCAGA GβTβAAβAAβ ATGTGGAβTC GβTGGAATCT 1440 CTCCβTββAC TGGAAAAGGA CACCGCCATG TββCAβCCβC AGATβCGβCT CAGTGCTCAC 1500 CACCβTβACβ CACAGCACCA GCAGCCAGTC ACAGGTGGCG βCCAβCACAC GCATGGTGCT 1560 TATCTCTGGC AAAGCTGCCA AβATCβCCAβ CAGACAGCCT GACAGCCACA TCACTTTACC 1620 TββCTATβTC TGGAGTAACT CAGAGCAGGA CTGCCTβCCA CACTCTTTCC ACGAββAβAC 1680 CAAβGAAGAT AGTGGGAGGC AGGGAGATGA TATTCTAATG GAGAAGCCTT CCAGGCCTAT 1740 GGAATCTAAC CCAGACACTβ AAGGATGCCA AGGAGAAACT GA6GATGTTC TCTGAATGGA 1800 CATTTGTGGC TGACTTTCAT GGGCTGGTCC AATGβCTββT TGTGTGAGAG GGCTTGGCTG 1860 ATACTCCTAT GCTTGAGTTC AAAGβCTβAA AATTCAβTTA AGGTGTTACT TAATAATAGT 1920 TTTTAββCTC CATGAATTGβ CTCCTβTAAA TACTAACGAC ATGAAAATβC AAGTGTCAAT 1980 GGAGTAGTTT ATTACCTTCT ATTGGCATCA AGTTTTCCTC TAAATTAATG TATGGTATTT 2040
GCTCTGTGAT TGTTCATTTT TTTCTGCTAC TTTTGGGTAG AAAAAAGATT CAATTGCTTG 2100
GCTGTAGCTT TCTCTCATAT ATATCACCCT AAATATAATG AAGATCTTTT AGTβTGTATC 2160
ATTTTCCTTT TAGAAACTAG TATTCTCTTA TTTCTTACTT TAATGTACTT CTATCACTGC 2220
ATTTATTTTG CCTGTGCATA GGAGCAATTA GGATCTAAAA AAATATATGG GAAβATAAAA 2280
GATCTAAGAA CAAGTACTTG CTββAAAATT AGTTGGCTGG ACATTGATAA AATAATGCAT 2340
TTATAACAAT TACATGTGTT TTTGGGAACA AGGAAAATTT CTCAAAAAAG AATATTTCAC 2400
ACATCCCTTC TTTTGAATGG CCTCTTTGTG ACCAGCCAβA CCTCAGGTCT TCACTCTTTC 2460
TTCTTTGTAA ACCATGTCAT GTGGAAAGAT TTCCTCAGTT AGTβAGCTTG TGTCTGCAAA 2520
TTGATTTTGT TTGTAATGTA TTTTGATAGC AAATCATGCT GCATCTATAT CTTTTTCTTG 2580
TTTGAGCTGT TACTACATTG TACATGGCAT GTGGGATCAA TTAAAAATTT GTTTTAAAAA 2640 T
A133 PROTEIN SEQUENCE
Gene name: parathyroid hormone receptor 2 Unigene number: Hs.159499 Protein Accession ft: NP_005039.1 Signal sequence: 1-25 Pfam domain: 7tm_2 [141-420] Transmembrane domains : 177-197, 228-250, 253-275, 280-302 , 320-342, 363 -385 , 398-419 Cellular Localization: plasma membrane
1 11 21 31 41 51
1 | 1 | 1 | 1 |1 1
MAGLβASLHV WGWLMLGSCL LARAQLDSDG TITIEEQIVL VLKAKVQCEL NITAQLQEGE 60 βNCFPEWDGL ICWPRGTVGK ISAVPCPPYI YDFNHKGVAF RHCNPNGTWD FMHSLNKTWA 120
NYSDCLRFLQ PDISIGKQEF FERLYVMYTV GYSISFGSLA VAILIIGYFR RLHCTRNYIH 180
MHLFVSFMLR ATSIFVKDRV VHAHIGVKEL ESLIMQDDPQ NSIEATSVDK SQYIGCKIAV 240
VMFIYFLATN YYWILVEGLY LHNLIFVAFF SDTKYLWGFI LIGWGFPAAF VAAWAVARAT 300
LADARCWELS AGDIKWIYQA PILAAIGLNF ILFLNTVRVL ATKIWETNAV GHDTRKQYRK 360
LAKSTLVLVL VFGVHYIVFV CLPHSFTGLG WEIRMHCELF FNSFQGFFVS IIYCYCNGEV 420
QAEVKKMWSR WNLSVDWKRT PPCGSRRCGS VLTTVTHSTS SQSQVAASTR MVLISGKAAK 480
IASRQPDSHI TLPGYVWSNS EQDCLPHSFH EETKEDSGRQ GDDILMEKPS RPMESNPDTE 540
GCQGETEDVL
A134 DNA sequence
Gene name: ESTs Unigene number: Hs.128899 Probeset Accession ft: AA983251 Nucleic Acid Accession ft: AA983251 Coding sequence : 1-1749 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I
ATGCTGTCTG G ICTTCTTGAT G IAGTCCCAGT ACCCACCACA G IAGCACAGTA CACTCCCββA 60 GGAAAGAAAC TTCCβTββGA GβCTTCCATC ββTβCGCACA CCTCCCGAGβ GCGAββCAβC 120 GACCGGGAGA GGGAGAGCCG βCCβGAββCT GCCGββCTCC TGTGGGACCG CGCTGCAGCC 180 GGGGAGGCGG AGAAGGGGAA CCGGGGCβAG CCGCCCGCCT GGATCCGCGC CCAGCAGCAG 240 CCGCββCCGC CGCCAGCTGG GCAGGCTCCC GGGACTGCGG CTGGGGGCGC GCAGGACCCT 300 CGCCTβCGTC CTGGACGTTC CCGGGGGAGG GTCCGGTTGC CAGTGAAACC TCCAGAGGCT 360 TCCGGACGAC AGCCCCGGGβ GCCTTCTβAC TGCATCCCβA GATTTCCATC AGCGAGTGCA 420 ACTCATAAGG CAGTCCCTAA GββGACCGGG CCACCGGCTG AGGACGGGGA TGGCTTAGGA 480 GCTCCTGGAC CTAGGGCCCG GCβTCGTCGC CTCCTGGGCG TCGCGGCAGA GGGGAGTGGC 540 CCGCGCGGAA AGCβCCGCGG GACAGTCAGT GACGAGGCCC GGGGGTCGCC GGGGCCACGA 600 CTTCTCGGAG ACCGTCCTGC GCTCTCTGGA GACGCβCTβT CCGCGCCCAG GGTGGTGCCA 660 TGTGGGGCGC TCGCCβCTCG TCCGTCTCCT CATCCTββAA CGCCGCTTCG CTCCTGCAGC 720 TGCTGCTGGC TGCGCTβCTβ GCGGCGββββ CGAGGGCCCA GCGβCGAGTA CTGCCACGβC 780 TGGCTGGACG CGCAGGGCβT CTGGCβCATC GGCTTCCAGT GTCCCGAGCβ CTTCβACGGC 840 GGCGACGCCA CCATCTGCTG CGβCAβCTGC GCGTTGCGCT ACTGCTGCTC CAGCGCCGAG 900 GCGCGCCTβG ACCAGβGCGG CTGCGACAAT GACCGCCAGC AGGGCGCTGG CGAGCCTGGC 960 CGGβCGGACA AAGACGGGCC CCGACGGCTC GGCAGGGCTT CATGTCTTAG GGGTACCCAA 1020 GGAGACGGCG AGGGTGCGCC CCCACCCGTβ AGGGCCTGGC AGCGGTGCTC CCCTGAAGGC 1080 TCCCCGAAAG GAAGGCAGCT CCTCAGGGCT TTCCCGGGGC TGCTGCCCCG TGCCAGACGC 1140 CGCβGATTCC CATCTTCTCC ACGCGGCGGC CCCTCTCCCC TGCAGCGGCC CGCCTTGCCC 1200 ATCTACGTGC CGTTCCTCAT TGTTGGCTCC GTGTTTGTCG CCTTTATCAT CTTGGGGTCC 1260 CTGGTGGCAG CCTGTTGCTG CAGATGTCTC CGGCCTAAGC AGGATCCCCA GCAGAGCCGA 1320 GCCCCAGGGG GTAACCGCTT GATGGAGACC ATCCCCATGA TCCCCAGTGC CAGCACCTCC 1380 CGGGGGTCGT CCTCACGCCA GTCCAGCACA GCTGCCAGTT CCAGCTCCAG CGCCAACTCC 1440 GGGGCCCGGG CGCCCCCAAC AAGGTCACAG ACCAACTGTT GCTTGCCGGA AGGGACCATG 1500 AACAACGTGT ATGTCAACAT GCCCACGAAT TTCTCTGTGC TGAACTGTCA GCAGGCCACC 1560 CAGATTGTGC CACATCAAGG GCAGTATCTβ CATCCCCCAT ACGTGGGGTA CACGGTGCAG 1620 CACGACTCTG TGCCCATGAC AβCTβTβCCA CCTTTCATGG ACGGCCTGCA GCCTGGCTAC 1680 AβGCAGATTC AGTCCCCCTT CCCTCACACC AACAGTGAAC AGAAGATGTA CCCAGCββTβ 1740 ACTGTATAAC CGAGAGTCAC TGGTGGGTTC CTTTACTGAA GGβAGACGAA GGCAGβββTβ 1800 GATTCTCGAG GTGGAAGTCC GCACATGTCG GTG6TATTTA TGβCACGATT CCTTTβGATG 1860 GCTTCATTTG CCCCCAGACT GTATGAAAAC ATCTCCβAAT TAGCATTTCT βGATATGTTT 1920 CATCCAGGGT ATCATTGATT TATGATGGAA AACCGGCCTC AGCTGGAGAT βACTβTβATβ 1980 TTGCTGATGG GTGTATAACA AATGCTTGAβ TCCGAAGTGC CCTTGAGATA TGGTTGACGA 2040 AAGAATTTTA TAAACTGATA AATTAAβGAT TTTTATTATG TTGTTATTAT TATTTCTTTT 2100 TTGTTβTTGA CTGCACAGGA TCAAAATGCC TGTTATCTCC CTTTTACTGG GACTTTTTTT 2160
TTTTTTTTAA TCAGACAGGG TCTTGCTCTG TTGCCCAβGC TGGAβTβCAβ 2220
TββTGCGATC TCGGCTCACT GCAACTTCAG CCTCCTGGAT TCAGGCAACA CTCCTCCCTC 2280 AGCCTCCCAC GTGGCTGGGA TTACAGβTGC CTGCCCCCAT GGCTAATTTT TTβTATTTTT 2340 TGTAGAGATG GGGTTTCACC ATGTTGGCTG GGCTGGTCTC ACTCTCCTGA CCTCAAGCAA 2400 TCTGCCTGTC TCAGCCTCCC AAAGTGCTGG GATTACAGGC GTGAGCCACC GCCCCCAGCC 2460 TGAβCCTTTT TTTTTTTCTA ATGCATCCAA GβTTAAβββG AAGACGCAAA TAACAGGACT 2520 ATTCTAAAAβ GAAACCTGTT TGAACTCTβT GAβATCAGTC ATCAGTCTCA GTATTCCACA 2580 GβCACACCTT AATTTCATTG TAAAAAβATA TATATATTTT GTCTATTTTT GTGCTTTTGG 2640 GGGCCTATTT TGTGCTTTTT TACCTTATGT AGAβATCTTA TTACAAAGTG ATTTTCTACA 2700 TTAAAAAGAG ACTGAAATAA ATTβTATAGT TACTTAACTA ATGAAβACAT TTCAGAACTC 2760 TGGGATGATT TTAATCTTβA AGTAGTAGGT GGTATAGTCA TAAAACCATT CATCCCCTTC 2820 TTGATTGTAT CTTAATTTTC TGGCTTTAAG GTGACATCTG AGAGGTAATG CATTCTTTTT 2880 TATATTGAAA TCATAAACTA TCACCCGCTβ CTTCTCTGAG TTACTTTTAA TTTTGCCTTG 2940 TββTTATββT TTCβCGTTTC CTTCTGTTTG βTTTTCAGAG CCCCATGTCT ATATAGTCCT 3000 GAβTβCAAβT AATTACTATA CTTGTAAATG AAGATCAGTA TTTCTGCCTA GATCTβATAA 3060 AAAAATTTTC TTGTCTTAGT TATAAAAATT CAAAGAAATG TGTTACAAAG ATACTTAβTA 3120 TAβCTCCTCA GCCATAACCT GAGACTTGGβ ATGAAATTTA AACCAGATAC βATTTACTTT 3180 GCAGATCATA ACβCTTTTTA TACTCTTGTT ATCAAAATGG CTTATTTTTC AGGCACTAAG 3240 GATTGTTAAG AGAAAAGCTT TTCAACβAAβ GATTGCCTTT CTTCTCCCAC ACTGTTCTTG 3300 ATTTCCTCTC TCTTTCAGGC CTCAACAGGC ACTGTATTCA TTGCCAATGT TCCAAATTAT 3360 CAAATTCAAβ TβAATTTATT TGTGTGTTCT TTACTTATAT AAAAAAAGAT AACTTTAAGG 3420 ATGTGCAAβT ACATTTCCAA CTGCTAGCAC AACCAGTATT TTGTAATTAA ACAAATCβCT 3480 GTATββTATβ βTCTTCTACA CATTTATGTC TATAGATATC TATCGATCAT CTTTCTATTC 3540 TβTTTCATβA CTGAATAATG TAAAACCAGT GTTGGCAATT ββTATCATCA ATGATACTCA 3600 TTTTTTAATA ACCAAAGGCA GGGGAAAATC ATTTTACTTA TTAATAAATA TTTTATGATβ 3660 TβAAAAAAAA AAAAAAAAAA AAAAAAAAAA
A135 Protein sequence Gene name: ESTs Unigene number: Hs.128899 Protein Accession ft: none found Signal sequence : 1-11 Transmembrane domains : 402-424 Cellular Localization: not determined
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I 1 I I I
MLSβFLMSPS TQHRAQYTPG GKKLPWEASI βAHTSRGRGS DRERESRPEA AGLLWDRAAA 60 GEAEKGNRGE PPAWIRAQQQ PRPPPAGQAP GTAAGGAQDP RLRPGRSRGR VRLPVKPPEA 120 SβRQPRβPSD CIPRFPSASA THKAVPKβTβ PPAEDGDGLG APGPRARRRR LLGVAAEGSβ 180 PRβKRRβTVS DEARGSPGPR LLGDRPALSG DALSAPRWP CβALAARPSP HPCTPLRSCS 240 CCWLRCWRRG RGPSβEYCHG WLDAQGVWRI GFQCPERFDG GDATICCGSC ALRYCCSSAE 300 ARLDQGGCDN DRQQGAGEPG RADKDGPRRL GRASCLRGTQ GDGEGAPPPV RAWQRCSPEG 360 SPKGRQLLRA FPGLLPRARR RGFPSSPRGG PSPLQRPALP IYVPFLIVGS VFVAFIILGS 420 LVAACCCRCL RPKQDPQQSR APGβNRLMET IPMIPSASTS RGSSSRQSST AASSSSSANS 480 GARAPPTRSQ TNCCLPEGTM NNVYVNMPTN FSVLNCQQAT QIVPHQGQYL HPPYVβYTVQ 540 HDSVPMTAVP PFMDβLQPGY RQIQSPFPHT NSEQKMYPAV TV
A136 DNA SEQUENCE
Cene name: selectin E (endothelial adhesion molecule 1)
Unigene number: Hs.89546 Probeset Accession ft: M24736
Nucleic Acid Accession ft: NM_000450
Coding sequence: 1-1833 (underlined sequences correspond to start and stop codons)
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ATGATTGCTT CACAGTTTCT CTCAGCTCTC ACTTTGGTGC 1 1
TTCTCATTAA AGAGAGTGGA 60
GCCTGGTCTT ACAACACCTC CACββAAGCT ATGACTTATG ATβAGGCCAG TGCTTATTGT 120
CAGCAAAGGT ACACACACCT GGTTGCAATT CAAAACAAAG AAGAβATTGA GTACCTAAAC 180
TCCATATTGA GCTATTCACC AAGTTATTAC TGGATTββAA TCAGAAAAGT CAACAATGTG 240
TGββTCTβGG TAββAACCCA GAAACCTCTG ACAGAAGAAG CCAAGAACTβ GGCTCCAGGT 300
GAACCCAACA ATAGGCAAAA AGATβAββAC TGCGTGGAGA TCTACATCAA GAGAGAAAAA 360
GATGTGGGCA TGTGGAATGA TGAβAββTβC AGCAAGAAGA AβCTTGCCCT ATGCTACACA 420
GCTGCCTβTA CCAATACATC CTGCAGTGGC CACGGTGAAT GTGTAβAβAC CATCAATAAT 480
TACACTTGCA AGTGTGACCC TββCTTCAGT GGACTCAAGT GTGAGCAAAT TGTGAACTGT 540
ACAGCCCTGG AATCCCCTβA GCATGGAAβC CTGGTTTGCA GTCACCCACT GGGAAACTTC 600
AGCTACAATT CTTCCTGCTC TATCAβCTβT GATAGGGβTT ACCTGCCAAG CAGCATGGAG 660
ACCATGCA6T GTATGTCCTC TGGAβAATββ AGTGCTCCTA TTCCAGCCTG CAATGTGGTT 720
GAGTGTGATG CTGTβACAAA TCCAGCCAAT GGGTTCGTGG AATβTTTCCA AAACCCTGGA 780
AGCTTCCCAT GGAACACAAC CTGTACATTT GACTGTGAAG AAGβATTTGA ACTAATGGGA 840
GCCCAGAGCC TTCAGTGTAC CTCATCTGGG AATTGGGACA ACGAβAAβCC AACGTGTAAA 900
GCTGTGACAT GCAGβGCCGT CCGCCAGCCT CAGAATGGCT CTGTGAGβTG CAGCCATTCC 960
CCTGCTGGAG AGTTCACCTT CAAATCATCC TGCAACTTCA CCTβTβAGGA AGGCTTCATG 1020
TTGCAGGGAC CAGCCCAGGT TGAATGCACC ACTCAAGGGC AGTGGACACA GCAAATCCCA 1080 βTTTβTβAAβ CTTTCCAGTG CACAGCCTTG TCCAACCCCG AGCGAGGCTA CATGAATTGT 1140
CTTCCTAGTG CTTCTGGCAG TTTCCGTTAT GGGTCCAGCT GTGAGTTCTC CTGTβAGCAG 1200
GβTTTTGTGT TβAAGββATC CAAAAGGCTC CAATGTGGCC CCACAGGGGA GTGGGACAAC 1260
GAGAAβCCCA CATGTGAAGC TGTGAβATGC GATGCTGTCC ACCAGCCCCC GAA6GGTTTG 1320
GTGAGGTGTG CTCATTCCCC TATTGGAGAA TTCACCTACA AGTCCTCTTG TβCCTTCAβC 1380
TGTβAGGAGG GATTTGAATT ATATGGATCA ACTCAACTTG AβTGCACATC TCAGβGACAA 1440
TGGACAGAAG AGGTTCCTTC CTGCCAAGTβ GTAAAATGTT CAAGCCTGGC AGTTCCGGGA 1500
AAGATCAACA TGAβCTGCAG TGGββAGCCC GTGTTTGGCA CTGTGTGCAA GTTCGCCTGT 1560
CCTGAAGGAT GGAC6CTCAA TββCTCTCCA GCTCGGACAT GTGGAGCCAC AGGACACTGG 1620
TCTGβCCTGC TACCTACCTG TGAAGCTCCC ACTGAGTCCA ACATTCCCTT GGTAGCTGβA 1680
CTTTCTGCTβ CTCGACTCTC CCTCCTβACA TTAGCACCAT TTCTCCTCTG GCTTCGGAAA 1740 TGCTTACGGA AAGCAAAGAA ATTTGTTCCT GCCAGCAGCT GCCAAAGCCT TGAATCAGAC GGAAGCTACC AAAAGCCTTC TTACATCCTT TAA
A137 Protein sequence: Gene name: Selectin E (endothelial adhesion molecule 1) Unigene number: HS.89546 Probeset Accession ft: M24736 Protein Accession ft: NP_000441 0 Signal sequence: 1-22 Transmembrane domains: 555-573 C-lectin domain: 23-139 Cellular Localization: plasma membrane 5
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I I I I I I
MIASQFLSAL TLVLLIKESG AWSYNTSTEA MTYDEASAYC QQRYTHLVAI QNKEEIEYLN 60
SILSYSPSYY WIGIRKVNNV WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK 120 0 DVGMWNDERC SKKKLALCYT AACTNTSCSG HGECVETINN YTCKCDPGFS βLKCEQIVNC 180
TALESPEHGS LVCSHPLGNF SYNSSCSISC DRGYLPSSME TMQCMSSGEW SAPIPACNW 240
ECDAVTNPAN βFVECFQNPG SFPWNTTCTF DCEEGFELMβ AQSLQCTSSG NWDNEKPTCK 300
AVTCRAVRQP QNGSVRCSHS PAGEFTFKSS CNFTCEEGFM LQGPAQVECT TQGQWTQQIP 360
VCEAFQCTAL SNPERGYMNC LPSASGSFRY GSSCEFSCEQ GFVLKGSKRL QCGPTGEWDN 420 5 EKPTCEAVRC DAVHQPPKGL VRCAHSPIβE FTYKSSCAFS CEEβFELYGS TQLECTSQGQ 480
WTEEVPSCQV VKCSSLAVPG KINMSCSGEP VFGTVCKFAC PEGWTLNGSA ARTCGATβHW 540
SGLLPTCEAP TESNIPLVAG LSAAGLSLLT LAPFLLWLRK CLRKAKKFVP ASSCQSLESD 600 GSYQKPSYIL 0 A138 DNA SEQUENCE:
Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H.sapiens]
Unigene number: Hs.100686
Probeset Accession if: AA487468
Nucleic Acid Accession ft: AA487468 5 Coding sequence: 55-555 (underlined sequences correspond to start and stop codons)
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I I I I I I 0 CGβCACCAAG AβCACTGGCC AAβTCAGCTT CTTCTGAGAβ AβTCTCTAGA AGACATGATG 60
CTACACTCAG CTTTGGGTCT CTGCCTCTTA CTCGTCACAG TTTCTTCCAA CCTTGCCATT 120
GCAATAAAAA AGGAAAAGAG GCCTCCTCAG ACACTCTCAA GAGGATGGGG AGATGACATC 180
ACTTGGGTAC AAACTTATGA AβAAβGTCTC TTTTATβCTC AAAAAAβTAA GAAGCCATTA 240
ATGGTTATTC ATCACCTGGA GβATTβTCAA TACTCTCAAG CACTAAAGAA AGTATTTGCC 300 5 CAAAATGAAG AAATACAAGA AATβGCTCAG AATAAGTTCA TCATGCTAAA CCTTATGCAT 360
GAAACCACTG ATAAGAATTT ATCACCTGAT GGGCAATATG TGCCTAGAAT CATGTTTGTA 420
GACCCTTCTT TAACAGTTAG AGCTGACATA GCTGGAAGAT ACTCTAACAG ATTGTACACA 480
TATGAβCCTC GGGATTTACC CCTATTGATA GAAAACATGA AGAAAGCATT AAβACTTATT 540
CAβTCAβAβC TATAAGAGAT GATAGAAAAA AGCCTTCACT TCAAAGAAGT CAAATTTCAT 600 0 GAAGAAAACC TCTGGCACAT TGACAAATAC TAAATGTGCA AGTATATAGA TTTTGTAATA 660
TTACTATTTA GTTTTTTTAA TGTGTTTGCA ATAGTCTTAT TAAAATAAAT GTTTTTTAAA 720 TCTGAAAAAA AAAAAAAAAA AAAAAAAAA 5 A139 Protein sequence: Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H. sapienε] Unigene number: Hs.100686 Probeεet Accession #: AA487468 Protein Accession ft: none found 0 Signal seguence : 1-23 Transmembrane domains: none found Cellular Localization: secreted 5 1 11 21 31 41 51
I I I I I I
MMLHSALGLC LLLVTVSSNL AIAIKKEKRP PQTLSRGWβD DITWVQTYEE GLFYAQKSKK 60 PLMVIHHLED CQYSQALKKV FAQNEEIQEM AQNKFIMLNL MHETTDKNLS PDGQYVPRIM 120 FVDPSLTVRA DIAGRYSNRL YTYEPRDLPL LIENMKKALR LIQSEL 0
A140 DNA SEQUENCE
Gene name: TMPRSS3a
Unigene number: Hs.298241
Probeset Accession ft: AI538613
/_> Nucleic Acid Accession ft: AB038157
Coding sequence: 202-1566 (underlined sequences correspond to start and stop codonε) o v 1 11 21 31 41 51
80 i i i i i i
ACCGGGCACC GGACGGCTCG GGTACTTTCG TTCTTAATTA GGTCATGCCC GTGTGAGCCA 60
GGAAAGGGCT GTGTTTATGG GAAGCCAβTA ACACTGTGGC CTACTATCTC TTCCGTGGTβ 120
CCATCTACAT TTTTβGGACT CGGGAATTAT GAGGTAGAGG TGGAGβCGGA GCCGGATβTC 180
AβAGGTCCTG AAATAGTCAC CATGGGβGAA AATGATCCGC CTGCTGTTGA AGCCCCCTTC 240 TCATTCCGAT CGCTTTTTGG CCTTGATGAT TTGAAAATAA GTCCTGTTGC ACCAGATGCA 300 GATGCTGTTG CTGCACAGAT CCTGTCACTβ CTGCCATTβA AGTTTTTTCC AATCATCGTC 360 ATTGGGATCA TTGCATTGAT ATTAβCACTG GCCATTββTC TGGGCATCCA CTTCβACTβC 420 TCAGGGAAGT ACAGATGTCG CTCATCCTTT AAGTGTATCG AGCTGATAGC TCβATβTβAC 480 GGAGTCTCGG ATTGCAAAGA CGGβGAGGAC GAGTACCCCT GTGTCCGββT GGGTGGTCAG 540 AATGCCGTβC TCCAGGTGTT CACAGCTGCT TCGTGβAAGA CCATGTGCTC CGATGACTGG 600 AAGGGTCACT ACGCAAATGT TGCCTGTGCC CAACTGGGTT TCCCAAGCTA TGTβAβTTCA 660 GATAACCTCA βAβTGAGCTC GCTGGAGGββ CAGTTCCGGG AGGAGTTTGT GTCCATCGAT 720 CACCTCTTCC CACATGACAA GGTGACTGCA TTACACCACT CAGTATATβT GAGGGAGGGA 780 TGTGCCTCTG GCCACGTGGT TACCTTGCAG TGCACAβCCT GTGGTCATAG AAGGGGCTAC 840 AβCTCACGCA TCGTGGGTGG AAACATGTCC TTGCTCTCGC AGTGGCCCTG GCAββCCAGC 900 CTTCAGTTCC AGGGCTACCA CCTGTGCGGG GGCTCTGTCA TCACGCCCCT GTGGATCATC 960 ACTGCTβCAC ACTGTGTTTA TGACTTGTAC CTCCCCAAβT CATGGACCAT CCAGGTβGGT 1020 CTAβTTTCCC TGTTGGACAA TCCAGCCCCA TCCCACTTGG TGGAGAAGAT TGTCTACCAC 1080 AβCAAGTACA AGCCAAAGAβ GCTGGGCAAT GACATCGCCC TTATGAAGCT GβCCβGCCCA 1140 CTCACGTTCA ATGAAATGAT CCAGCCTGTG TGCCTGCCCA ACTCTGAAGA βAACTTCCCC 1200 GATGGAAAAG TGTβCTGGAC GTCAGGATGG GβGGCCACAβ AGGATGGAGC AββTGACGCC 1260 TCCCCTGTCC TGAACCACGC GβCCGTCCCT TTGATTTCCA ACAAGATCTC CAACCACAGG 1320 GACGTGTACG GTGGCATCAT CTCCCCCTCC ATGCTCTGCG CGGGCTACCT GACGGGTGGC 1380 GTββACACCT GCCAGGGGGA CAGCGGGGGG CCCCTGGTβT GTCAAβAβAG GAGGCTGTGG 1440 AAβTTAGTGG βAβCβACCAβ CTTTGGCATC βGCTGCGCAβ AGGTβAACAA GCCTGGGGTG 1500 TACACCCGTG TCACCTCCTT CCTGGACTGG ATCCACGAGC AβATGGAGAG AGACCTAAAA 1560 ACCTGAAGAG GAAGGGGACA AGTAGCCACC TβAβTTCCTβ AGGTGATGAA GACAGCCCGA 1620 TCCTCCCCTG GACTCCCGTG TAGβAACCTβ CACACGAGCA GACACCCTTG GAβCTCTGAG 1680 TTCCGGCACC AGTAGCAGGC CCGAAAGAGG CACCCTTCCA TCTGATTCCA βCACAACCTT 1740 CAAGCTGCTT TTTGTTTTTT GTTTTTTTGA GGTGGAGTCT CGCTCTGTTG CCCAGGCTGG 1800 AGTGCAGTGG CβAAATCCCT GCTCACTGCA GCCTCCGCTT CCCTββTTCA AGCGATTCTC 1860 TTGCCTCAGC TTCCCCAβTA GCTGGGACCA CAGGTGCCCβ CCACCACACC CAACTAATTT 1920 TTGTATTTTT AGTAGAGACA GGβTTTCACC ATGTTGGCCA GGCTGCTCTC AAACCCCTGA 1980 CCTCAAATGA TGTGCCTGCT TCAβCCTCCC ACAGTGCTGG GATTACAβGC ATGGGCCACC 2040 ACGCCTAGCC TCACGCTCCT TTCTGATCTT CACTAAGAAC AAAAGAAGCA GCAACTTGCA 2100 AGGGCGGCCT TTCCCACTββ TCCATCTGGT TTTCTCTCCA GβGGTCTTGC AAAATTCCTG 2160 ACGAβATAAG CAβTTATβTβ ACCTCACGTG CAAAGCCACC AACAGCCACT CAGAAAAGAC 2220 GCACCAβCCC AGAAGTGCAG AACTGCAGTC ACTGCACGTT TTCATCTCTA GGGACCAGAA 2280 CCAAACCCAC CCTTTCTACT TCCAAGACTT ATTTTCACAT GTGGGGAGGT TAATCTAββA 2340 ATβACTCβTT TAAGGCCTAT TTTCATGATT TCTTTGTAGC ATTTGGTGCT TGACGTATTA 2400 TTGTCCTTTG ATTCCAAATA ATATGTTTCC TTCCCTCAAA AAAAAAAAAA AAAAAAAAAA 2460 AAAAAAAA
A141 Protein sequence: Gene name: TMPRSS3a Unigene number: Hs.298241 Probeset Accession it: AI538613 Protein Accession it : BAB20077 Signal sequence : none found Transmembrane domains: 43-65, 239-261 Tryp_SPc domain: 216-444 Cellular Localization: plasma membrane
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MGENDPPAVE I I I I I
APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP IIVIGIIALI 60 LALAIGLGIH FDCSGKYRCR SSFKCIELIA RCDGVSDCKD GEDEYRCVRV GGQNAVLQVF 120 TAASWKTMCS DDWKGHYANV ACAQLGFPSY VSSDNLRVSS LEGQFREEFV SIDHLLPDDK 180 VTALHHSVYV REGCASGHW TLQCTACGHR RGYSSRIVGG NMSLLSQWPW QASLQFQGYH 240 LCGGSVITPL WIITAAHCVY DLYLPKSWTI QVGLVSLLDN PAPSHLVEKI VYHSKYKPKR 300 LGNDIALMKL AGPLTFNEMI QPVCLPNSEE NFPDGKVCWT SGWGATEDGA GDASPVLNHA 360 AVPLISNKIC NHRDVYGGII SPSMLCAGYL TGGVDSCQGD SGGPLVCQER RLWKLVGATS 420 FGIGCAEVNK PGVYTRVTSF LDWIHEQMER DLKT
A142 DNA SEQUENCE Gene name : ESTs ; Weakly similar to LITHOSTATHINE 1 BETA PRECURSOR [H. sapiens] Unigene number : Hs .105484 Probeset Accession ft : AA314779
Nucleic Acid Accession # : none found
Coding sequence : 103-579 (underlined sequences correspond to start and stop codons)
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I I I I I I
CCAAACAGAT TTGCAβATCA AGGAGAACCC AGGAGTTTCA AAGAAGCGCT AGTAAGGTCT 60 CTβAGATCCT TGCACTAGCT ACATCCTCAG GβTAββAGGA AGATGGCTTC CAGAAβCATG 120 CGGCTGCTCC TATTGCTGAG CTGCCTGGCC AAAACAGβAG TCCTGGGTGA TATCATCATβ 180 AGACCCAGCT GTGCTCCTGG ATGGTTTTAC CACAAGTCCA ATTGCTATGG TTACTTCAGG 240 AAGCTGAGGA ACTGGTCTGA TGCCGAGCTC GAGTGTCAGT CTTACGGAAA CββAβCCCAC 300 CTGβCATCTA TCCTGAGTTT AAAGGAAGCC AGCACCATAG CAGAGTACAT AAGTβGCTAT 360 CAGAGAAβCC AGCCGATATG GATTGGCCTG CACGACCCAC AGAAβAββCA GCAβTGGCAG 420 TGGATTGATβ GGGCCATβTA TCTGTACAGA TCCTββTCTβ βCAAβTCCAT GGGTGGGAAC 480 AAGCACTGTG CTGAGATGAG CTCCAATAAC AACTTTTTAA CTTGGAGCAG CAACGAATGC 540 AACAAGCGCC AACACTTCCT βTGCAAGTAC CGACCATAGA GCAAβAATCA AGATTCTGCT 600 AACTCCTGCA CCAGCCCCGT CCTCTTCCTT TCTGCTAGCC TGGCTAAATC TGCTCATTAT 660 TTCAGAGGGG AAACCTAGCA AACTAAGAGT GATAAGββCC CTACTACACT GβCTTTTTTA 720 GGCTTAGAGA CAGAAACTTT AGCATTGGGC CCAGTAGTGG CTTCTAGCTC TAAATGTTTG 780 CCCCβCCATC CCTTTCCACA GTATCCTTCT TCCCTCCTCC CCTGTCTCTG GCTGTCTCGA 840 βCAGTCTAGA ACAGTGCATC TCCAGCCTAT GAAACAGCTG GβTCTTTGGC CATAAGAAGT 900 AAAGATTTGA AGACAGAAGG AAGAAACTCA GGAGTAAGCT TCTAGACCCC TTCAGCTTCT 960 ACACCCTTCT GCCCTCTCTC CATTGCCTGC ACCCCACCCC AGCCACTCAA CTCCTGCTTG 1020 TTTTTCCTTT GβCCATAGGA AGGTTTACCA GTAGAATCCT TGCTAGGTTG ATGTGGGCCA 1080 TACATTCCTT TAATAAACCA TTGTGTACAT AAGAGAAAAA AAAAAAAAAA AAAAAAAAAA
A143 Protein sequence: Gene name: ESTs; Weakly similar to LITHOSTATHINE 1 BETA PRECURSOR [H.sapiens] Unigene number: Hs.105484 Probeset Accession ft : AA314779 Protein Accession ft: none found Signal sequence : 1-22 Transmembrane domains : none found C-type lectin domain: 47-156 Cellular Localization: secreted
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I I I i 1 I I
MASRSMRLLL LLSCLAKTGV LGDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS 60
YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG 120 KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
A144 DNA SEQUENCE Gene name: Cadherin 3, P-cadherin (placental) Unigene number: Hs.2877 Probeset Accession ft : X63629 Nucleic Acid Accession ft: X63629 Coding sequence: 54-2543 (start and stop codons are underlined)
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I I I I I
GCββAACACC GGCCCGCCGT CGCGGCAGCT GCTTCACCCC TCTCTCTGCA GCCATGβGGC 60
TCCCTCGTGG ACCTCTCGCG TCTCTCCTCC TTCTCCAGβT TTGCTGGCTG CAGTGCGCGG 120
CCTCCGAGCC GTGCCGGGCG GTCTTCAGGG AGGCTGAAGT GACCTTGGAG GCGGGAGGCC 180
CGGAGCAGGA GCCCGGCCAG GCGCTGGββA AAGTATTCAT GGGCTGCCCT GGGCAAGAGC 240
CAGCTCTβTT TAGCACTGAT AATGATGACT TCACTGTβCβ GAATGGCGAG ACAGTCCAGG 300
AAAGAAGGTC ACTGAAGGAA AGGAATCCAT TβAAβATCTT CCCATCCAAA CGTATCTTAC 360
GAAGACACAA GAGAGATTGG GTGGTTGCTC CAATATCTβT CCCTGAAAAT GGCAAGGGTC 420
CCTTCCCCCA GAβACTβAAT CAGCTCAAGT CTAATAAAGA TAGAGACACC AAGATTTTCT 480
ACAGCATCAC GβββCCββββ GCAGACAβCC CCCCTGAGGG TGTCTTCGCT βTAGAGAAGG 540
ACACAGβCTβ GTTGTTGTTG AATAAβCCAC TGGACCGGGA GGAGATTGCC AAGTATβAGC 600
TCTTTGGCCA CGCTβTβTCA βAGAATGGTG CCTCAGTGGA GGACCCCATG AACATCTCCA 660
TCATCGTGAC CβACCAβAAT GACCACAAGC CCAAGTTTAC CCAGGACACC TTCCGAGGGA 720
GTGTCTTAGA GGGAGTCCTA CCAGGTACTT CTGTGATGCA GGTGACAGCC ACAGATGAGG 780
ATGATGCCAT CTACACCTAC AATGGGGTGG TTGCTTACTC CATCCATAβC CAAGAACCAA 840
AGGACCCACA CGACCTCATG TTCACAATTC ACCGGAβCAC AGGCACCATC AGCGTCATCT 900
CCAGTGGCCT GGACCGGGAA AAAGTCCCTG AGTACACACT GACCATCCAG GCCACAGACA 960
TGGATGGGGA CGGCTCCACC ACCACGGCAG TGGCAβTAβT GGAGATCCTT GATGCCAATG 1020
ACAATGCTCC CATGTTTGAC CCCCAGAAβT ACGAβGCCCA TGTGCCTGAG AATGCAGTGG 1080
GCCATβAβGT GCAGAGGCTG ACGGTCACTG ATCTGGACGC CCCCAACTCA CCAGCGTββC 1140 βTGCCACCTA CCTTATCATG GGCGGTGACG ACGβββACCA TTTTACCATC ACCACCCACC 1200
CTGAGAGCAA CCAGGGCATC CTGACAACCA GGAAβGGTTT GGATTTTGAG GCCAAAAACC 1260
AGCACACCCT GTACGTTGAA GTGACCAACG AGGCCCCTTT TGTGCTGAAG CTCCCAACCT 1320
CCACAGCCAC CATAGTββTC CACGTGGAGG ATGTGAATGA GGCACCTGTG TTTGTCCCAC 1380
CCTCCAAAGT CβTTβAGGTC CAGGAGGGCA TCCCCACTGG GGAGCCTGTβ TGTGTCTACA 1440
CTGCAGAAGA CCCTGACAAG GAGAATCAAA AGATCAGCTA CCGCATCCTG AGAGACCCAG 1500
CAGGGTGGCT AGCCATGβAC CCAGACAGTG GGCAGGTCAC AGCTGTGGGC ACCCTCGACC 1560
GTGAGGATGA GCAGTTTβTG AGGAACAACA TCTATGAAGT CATGGTCTTG GCCATGGACA 1620
ATGGAAGCCC TCCCACCACT GGCACGββAA CCCTTCTβCT AACACTGATT GATGTCAACβ 1680
ACCATGGCCC AGTCCCTβAG CCCCβTCAGA TCACCATCTG CAACCAAAGC CCTβTβCGCC 1740
ACβTβCTβAA CATCACGGAC AAββACCTβT CTCCCCACAC CTCCCCTTTC CAGGCCCAGC 1800
TCACAβATGA CTCAGACATC TACTββACβG CAGAGGTCAA CGAGGAAGGT GACACAGTGG 1860
TCTTGTCCCT GAAGAAGTTC CTGAAGCAGβ ATACATATGA CGTGCACCTT TCTCTGTCTβ 1920
ACCATGGCAA CAAAGAGCAG CTGACGGTGA TCAGGGCCAC TGTβTGCGAC TGCCATGGCC 1980
ATGTCGAAAC CTGCCCTGGA CCCTGβAAAG GAGGTTTCAT CCTCCCTGTG CTGGGGGCTG 2040
TCCTGGCTCT GCTGTTCCTC CTGCTGGTGC TGCTTTTGTT GGTGAβAAAβ AAGCGGAAGA 2100
TCAAGGAGCC CCTCCTACTC CCAGAAβATG ACACCCGTGA CAACGTCTTC TACTATGGCG 2160
AAGAGGGβββ TGGCGAAGAG GACCAGGACT ATGACATCAC CCAGCTCCAC CGAGGTCTGG 2220
AββCCAββCC GGAGGTGGTT CTCCGCAATG ACGTGGCACC AACCATCATC CCGACACCCA 2280
TGTACCGTCC TAGGCCAGCC AACCCAGATG AAATCGGCAA CTTTATAATT GAGAACCTGA 2340
AGGCGGCTAA CACAGACCCC ACAGCCCCGC CCTACGACAC CCTCTTGGTG TTCGACTATG 2400
AβGGCAGCβG CTCCGACGCC GCGTCCCTGA GCTCCCTCAC CTCCTCCGCC TCCGACCAAG 2460
ACCAAGATTA CGATTATCTG AACGAβTGGG GCAGCCGCTT CAAGAAGCTG GCAGACATGT 2520
ACGGTGβCββ GGAGGACGAC TAGGCGGCCT GCCTGCAGGG CTGGGGACCA AACGTCAGGC 2580
CACAGAGCAT CTCCAAGGGG TCTCAGTTCC CCCTTCAGCT GAGGACTTCG GAGCTTGTCA 2640
GGAAGTββCC GTAGCAACTT GGCGGAGACA GGCTATGAGT CTGACGTTAG AGTGβTTGCT 2700
TCCTTAGCCT TTCAGGATGG AGGAATβTGG GCAGTTTGAC TTCAGCACTβ AAAACCTCTC 2760
CACCTβββCC AGGGTTβCCT CAGAGGCCAA GTTTCCAGAA GCCTCTTACC TGCCGTAAAA 2820
TGCTCAACCC TGTGTCCTGG GCCTβββCCT GCTGTGACTG ACCTACAGTG GACTTTCTCT 2880
CTGGAATGGA ACCTTCTTAG GCCTCCTGGT GCAACTTAAT AATGCTATCT 2940 TCAAAACGTT AGAGAAAGTT CTTCAAAAGT GCAGCCCAGA GCTGCTβGGC CCACTGGCCG 3000
TCCTGCATTT CTGGTTTCCA GACCCCAATG CCTCCCATTC GGATGGATCT CTGCGTTTTT 3060
ATACTGAGTG TGCCTAGGTT GCCCCTTATT TTTTATTTTC CCTGTTGCGT TGCTATAGAT 3120 GAAβGGTGAβ GACAATCGTG TATATGTACT AGAACTTTTT TATTAAAβAA A
A145 Protein sequence: βene name : Cadherin 3, P-cadherin (placental) Unigene number: Hs.2877 Probeset Accession #: X63629 Protein Accession if : CAA45177 Signal sequence : 1-24 Transmembrane domain: 659-675
Cellular localization: plasma membrane
1 11 21 31 41 51 1 1 | 1 | 1 11 1 | 1 MGLPRGPLAS LLLLQVCWLQ CAASEPCRAV FREAEVTLEA ββAEQEPβQA LGKVFMGCPG 60
QEPALFSTDN DDFTVRNGET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENG 120
KβPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK 180
YELFGHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RGSVLEGVLP GTSVMQVTAT 240
DEDDAIYTYN GWAYSIHSQ EPKDPHDLMF TIHRSTGTIS VISSGLDREK VPEYTLTIQA 300
TDMDGDGSTT TAVAWEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP 360
AWRATYLIMG GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL 420
PTSTATIWH VEDVNEAPVF VPPSKWEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR 480
DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTβ TGTLLLTLID 540
VNDHGPVPEP RQITICNQSP VRHVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD 600
TWLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL 660
GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YGEEGGGEED QDYDITQLHR 720 βLEARPEWL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF 780
DYEβSβSDAA SLSSLTSSAS DQDQDYDYLN EWβSRFKKLA DMYGGGEDD
A146 DNA SEQUENCE:
Gene name: TTK protein kinase Unigene number: Hs.169840 Probeεet Accession #: M86699 Nucleic Acid Accession #: NM_003318 Coding sequence: 1026-3551 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
GβAATTCCTT TTTGAGATGG AGTTTCACTC TTGTTGβCCA βGCTGGAβTG 60
CAATGGCACA ATCTCAGCTT ACTGCAACCT CCGCCTCCCG GβTTCAAGCG ATTCTCCTβC 120
CTCAGCCTCT CAAGTAGCTG GGATTACAGG CATGTGCCAC CACCCCTGGC TAACTAATTT 180
CTTTTCTATT TAGTAGAGAT GGGGTTTCAC CATGTTGGTC AGGCTGGTCT TGAACTCCTG 240
ACCTCAGGTG ATCCACTTGC CTTGGCCTCC CAAAGTGCTA GGATTACAGC CGTGAAACTG 300
TGCCTGGCTG ATTCTTTTTT TGTTGTTGGA TTTTTGAAAC AGGGTCTCCC TTGGTCGCCC 360
AGGCTGβAGT GCAGTGGTGC GATCTTGGCT CACTATAACC TCCACCTCCT GGTTTCAAGT 420
GATCCTCCCA CTTTAGCCTC CTGAGTAGCT GTGATTACAβ GCGTGCACCA CCACACCCGG 480
CTAATTTTTG TATTTTTATT AGAβACAGGG TTTCACCATG TTGGCCAGGC TGTTCTCAAA 540
CTCCTGGACT CAAGGGATCC GCCTβCCTCC ACTTCCCAAA GTCCCGAGAT TACAGGTGTG 600
AGTCACCATG CCTGACCTTA TAATTCTTAA GTCATTTTTT CTGGTCCATT TCTTCCTTAG 660
GGTCCTCACA ACAAATCTGC ATTAGGCGGT ACAATAATCC TTAACTTCAT GATTCACAAA 720
AG6AAGATGA AGTGATTCAT GATTTAGAAA GβGGAAβTAβ TAAβCCCACT GCACACTCCT 780
GGATGATGAT CCTAAATCCA GATACAβTAA AAATGGββTA TGGGAAβGTA GAATACAAAA 840
TTTGβTTTAA ATTAATTATC TAAATATCTA AAAACATTTT TGGATACATT GTTβATβTGA 900
ATGTAAGACT GTACAGACTT CCTAGAAAAC AGTTTGGGTT CCATCTTTTC ATTTCCCCAG 960
TGCAGTTTTC TGTAβAAATβ GAATC∞AGG ATTTAAGTGG CAGAGAATTG ACAATTGATT 1020
CCATAATGAA CAAAGTGAGA GACATTAAAA ATAAGTTTAA AAATGAAGAC CTTACTGATG 1080
AACTAAGCTT GAATAAAATT TCTGCTGATA CTACAGATAA CTCGGGAACT GTTAACCAAA 1140
TTATGATGAT GGCAAACAAC CCAGAGGACT GGTTβAGTTT GTTGCTCAAA CTAGAGAAAA 1200
ACAGTGTTCC GCTAAGTGAT GCTCTTTTAA ATAAATTGAT TGGTCGTTAC AGTCAAGCAA 1260
TTGAAGCGCT TCCCCCAGAT AAATATGGCC AAAATGAGAG TTTTGCTAGA ATTCAAGTGA 1320
GATTTGCTGA ATTAAAAGCT ATTCAAGAGC CAGATGATGC ACGTGACTAC TTTCAAATGβ 1380
CCAGAGCAAA CTGCAAGAAA TTTGCTTTTG TTCATATATC TTTTGCACAA TTTGAACTGT 1440
CACAAGGTAA TGTCAAAAAA AGTAAACAAC TTCTTCAAAA AGCTGTAGAA CGTGGAGCAβ 1500
TACCACTAGA AATGCTGGAA ATTGCCCTGC GGAATTTAAA CCTCCAAAAA AAGCAGCTGC 1560
TTTCAGAGGA GGAAAAGAAG AATTTATCAG CATCTACG6T ATTAACTGCC CAAβAATCAT 1620
TTTCCGGTTC ACTTGGGCAT TTACAGAATA GGAACAACAG TTβTβATTCC AGAGGACAβA 1680
CTACTAAAGC CAGGTTTTTA TATGGAGAGA ACATGCCACC ACAAGATGCA GAAATAGGTT 1740
ACCGGAATTC ATTβAβACAA ACTAACAAAA CTAAACAβTC ATGCCCATTT GGAAGAGTCC 1800
CAGTTAACCT TCTAAATAGC CCAGATTGTG ATGTGAAGAC AGATGATTCA GTTβTACCTT 1860
GTTTTATGAA AAGACAAACC TCTAGATCAG AATGCCGAGA TTTGGTTGTG CCTGGATCTA 1920
AACCAAGTGG AAATGATTCC TGTβAATTAA GAAATTTAAA GTCTGTTCAA AATAβTCATT 1980
TCAAGGAACC TCTGGTGTCA βATGAAAAGA GTTCTGAACT TATTATTACT βATTCAATAA 2040
CCCTGAAGAA TAAAACGGAA TCAAGTCTTC TAβCTAAATT AGAAGAAACT AAAGAGTATC 2100
AAGAACCAGA GGTTCCAGAβ AGTAACCAGA AACAGTGGCA AGCTAAGAGA AAGTCAGAGT 2160
GTATTAACCA GAATCCTGCT GCATCTTCAA ATCACTGGCA GATTCCGGAβ TTAGCCCGAA 2220
AAGTTAATAC AGAGCAGAAA CATACCACTT TTGAGCAACC TβTCTTTTCA GTTTCAAAAC 2280
AGTCACCACC AATATCAACA TCTAAATGGT TTGACCCAAA ATCTATTTβT AAGACACCAA 2340 GCAGCAATAC CTTGGATGAT TACATGAGCT GTTTTAGAAC TCCAGTT6TA AAβAATβACT 2400
TTCCACCTGC TTβTCAGTTG TCAACACCTT ATGGCCAACC TGCCTGTTTC CAGCAGCAAC 2460
AGCATCAAAT ACTTGCCACT CCACTTCAAA ATTTACAGGT TTTAGCATCT TCTTCAGCAA 2520
ATGAATGCAT TTCGβTTAAA CβAAGAATTT ATTCCATATT AAAGCAGATA GGAAGTGGAG 2580
GTTCAAGCAA GGTATTTCAG GTGTTAAATG AAAAβAAACA βATATATGCT ATAAAATATG 2640
TGAACTTAGA AGAAGCAβAT AACCAAACTC TTGATAGTTA CCGGAACGAA ATAGCTTATT 2700
TβAATAAACT ACAACAACAC AGTGATAAGA TCATCCGACT TTATGATTAT GAAATCACGG 2760
ACCAGTACAT CTACATGGTA ATGGAGTGTG GAAATATTGA TCTTAATAGT TGGCTTAAAA 2820
AGAAAAAATC CATTGATCCA TGββAACCCA AGAGTTACTG GAAAAATATG TTAGAGGCAG 2880
TTCACACAAT CCATCAACAT GβCATTGTTC ACAGTGATCT TAAACCAGCT AACTTTCTGA 2940
TAβTTGATGG AATGCTAAAG CTAATTGATT TTGGGATTβC AAACCAAATβ CAACCAβATA 3000
CAACAAβTGT TGTTAAAGAT TCTCAGGTTG GCACAGTTAA TTATATβCCA CCAGAAGCAA 3060
TCAAAGATAT GTCTTCCTCC AβAβAGAATG GGAAATCTAA GTCAAAβATA AGCCCCAAAA 3120
GTGATGTTTG GTCCTTAGGA TβTATTTTGT ACTATATGAC TTACGGGAAA ACACCATTTC 3180
AGCAGATAAT TAATCAGATT TCTAAATTAC ATGCCATAAT TGATCCTAAT CATGAAATTG 3240
AATTTCCCGA TATTCCAGAG AAAGATCTTC AAGATGTβTT AAAβTGTTGT TTAAAAAGGG 3300
ACCCAAAACA GAββATATCC ATTCCTGAGC TCCTGGCTCA TCCATATGTT CAAATTCAAA 3360
CTCATCCAGT TAACCAAATG GCCAAGGGAA CCACTGAAGA AATGAAATAT GTTCTGGβCC 3420
AACTTGTTGG TCTGAATTCT CCTAACTCCA TTTTGAAAβC TβCTAAAACT TTATATβAAC 3480
ACTATAGTGG TGGTGAAAGT CATAATTCTT CATCCTCCAA βACTTTTGAA AAAAAAAGββ 3540
GAAAAAAATG ATTTGCAGTT ATTCGTAATG TCAGATAGGA GβTATAAAAT ATATTβGACT 3600
GTTATACTCT TβAATCCCTG TGGAAATCTA CATTTGAAGA CAACATCACT CTGAAGTGTT 3660
ATCAβCAAAA AAAATTCAGT GAβATTATCT TTAAAAGAAA ACTGTAAAAA TAGCAACCAC 3720
TTATGβCACT GTATATATTG TAGACTTGTT TTCTCTGTTT TATGCTCTTβ TGTAATCTAC 3780
TTGACATCAT TTTACTCTTG GAATAGTGGβ TGGATAβCAA GTATATTCTA AAAAACTTTG 3840 TAAATAAAGT TTTGTGGCTA AAATGA
A147 Protein sequence :
Gene name: TTK protein kinase
Unigene number: Hs.169840
Probeset Accesεion #: M86699
Protein Accession ft: NP_003309
Signal sequence: none found
Transmembrane domains : none found
Protein Kinase Domain: 510-775
Cellular Localization: cytoplasmic and nuclear
MNKVRDIKNK FKNEDLTDEL SLNKISADTT DNSGTVNQIM MMANNPEDWL SLLLKLEKNS 60
VPLSDALLNK LIGRYSQAIE ALPPDKYGQN ESFARIQVRF AELKAIQEPD DARDYFQMAR 120
ANCKKFAFVH ISFAQFELSQ GNVKKSKQLL QKAVERGAVP LEMLEIALRN LNLQKKQLLS 180
EEEKKNLSAS TVLTAQESFS GSLGHLQNRN NSCDSRGQTT KARFLYGENM PPQDAEIGYR 240
NSLRQTNKTK QSCPFGRVPV NLLNSPDCDV KTDDSWPCF MKRQTSRSEC RDLWPGSKP 300
SGNDSCELRN LKSVQNSHFK EPLVSDEKSS ELIITDSITL KNKTESSLLA KLEETKEYQE 360
PEVPESNQKQ WQAKRKSECI NQNPAASSNH WQIPELARKV NTEQKHTTFE QPVFSVSKQS 420
PPISTSKWFD PKSICKTPSS NTLDDYMSCF RTPWKNDFP PACQLSTPYG QPACFQQQQH 480
QILATPLQNL QVLASSSANE CISVKGRIYΞ ILKQIGSββS SKVFQVLNEK KQIYAIKYVN 540
LEEADNQTLD SYRNEIAYLN KLQQHSDKII RLYDYEITDQ YIYMVMECGN IDLNSWLKKK 600
KSIDPWERKS YWKNMLEAVH TIHQHGIVHS DLKPANFLIV DGMLKLIDFG IANQMQPDTT 660
SWKDSQVGT VNYMPPEAIK DMSSSRENGK SKSKISPKSD VWSLGCILYY MTYGKTPFQQ 720
IINQISKLHA IIDPNHEIEF PDIPEKDLQD VLKCCLKRDP KQRISIPELL AHPYVQIQTH 780
PVNQMAKGTT EEMKYVLGQL VGLNSPNSIL KAAKTLYEHY SGGESHNSSS SKTFEKKRβK 840 K
A148 DNA SEQUENCE
Gene name: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
Unigene number: Hs.258583
Probeset Accession ft: NM_012152
Nucleic Acid Accession #: NM_012152
Coding sequence: 43-1104 (underlined sequences correspond to start and εtop codons)
1 11 21 31 41 51
I I I I I I
CTTCTTTAAA TTTCTTTCTA GGATGTTCAC TTCTTCTCCA CAATGAATGA GTGTCACTAT 60
GACAAGCACA TGβACTTTTT TTATAATAGG AGCAACACTG ATACTGTCGA TGACTGGACA 120
GGAACAAAGC TTβTGATTGT TTTGTβTGTT GGGACGTTTT TCTβCCTGTT TATTTTTTTT 180
TCTAATTCTC TGGTCATCGC GGCAGTGATC AAAAACAGAA AATTTCATTT CCCCTTCTAC 240
TACCTGTTGG CTAATTTAGC TGCTGCCGAT TTCTTCGCTβ GAATTGCCTA TGTATTCCTG 300
ATβTTTAACA CAGGCCCAGT TTCAAAAACT TTGACTGTCA ACCGCTGGTT TCTCCGTCAG 360
GββCTTCTGG ACAGTAGCTT βACTβCTTCC CTCACCAACT TβCTGGTTAT CGCCGTββAG 420
AGGCACATGT CAATCATGAG GATGCGββTC CATAGCAACC TGACCAAAAA GAββGTGACA 480
CTGCTCATTT TGCTTβTCTG GGCCATCGCC ATTTTTATGG GGGCGGTCCC CACACTGGGC 540
TGGAATTGCC TCTGCAACAT CTCTGCCTGC TCTTCCCTGG CCCCCATTTA CAGCAGGAGT 600
TACCTTGTTT TCTGβACAGT GTCCAACCTC ATGGCCTTCC TCATCATGGT T6TGGTGTAC 660
CTGCββATCT ACβTGTACGT CAAGAGGAAA ACCAACGTCT TGTCTCCGCA TACAAGTGGG 720
TCCATCAGCC GCCGβAββAC ACCCATGAAG CTAATGAAGA CβGTGATGAC TGTCTTA6GG 780
GCGTTTGTGG TATβCTββAC CCCGGGCCTβ GTGGTTCTCC TCCTCGACGG CCTGAACTβC 840
AGGCAGTGTG GCGTGCAGCA TCTGAAAAGG TGGTTCCTGC TGCTGGCGCT GCTCAACTCC 900
GTCGTGAACC CCATCATCTA CTCCTACAAG GACGAGβACA TGTATGGCAC CAT6AAGAAG 960
ATGATCTGCT GCTTCTCTCA GGAGAACCCA GAGAGGCGTC CCTCTCGCAT CCCCTCCACA 1020
GTCCTCAGCA GGAGTGACAC AGGCAGCCAG TACATAGAGG ATAGTATTAG CCAAGβTGCA 1080 GTCTGCAATA AAAβCACTTC CTAAACTCTG CATβCCTCTC GGCCCACCCA GGTGATGACT GTCTTAGG
A149 Protein sequence: βene name : endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7 Unigene number: Hs.258583 Probeset Accession ft: NM_012152 Protein Accession ft: NP_036284 Signal sequence : none found Transmembrane domains : 31-53, 66-88, 150-172, 190-211, 239-261, 277-295 Cellular Localization: plasma membrane 1 11 21 31 41 51
I I I I I I
MNECHYDKHM DFFYNRSNTD TVDDWTGTKX, VIVLCVGTFF CLFIFFSNSL VIAAVIKNRK 60
FHFPFYYLLA NLAAADFFAG IAYVFLMFNT GPVSKTLTVN RWFLRQGLLD SSLTASLTNL 120
LVIAVERHMS IMRMRVHSNL TKKRVTLLIL LVWAIAIFMG AVPTLGWNCL CNISACSSLA 180 PIYSRSYLVF WTVSNLMAFL IMVWYLRIY VYVKRKTNVL SPHTSGSISR RRTPMKLMKT 240
VMTVLβAFW CWTPGLWLL LDGLNCRQCG VQHVKRWFLL LALLNSWNP IIYSYKDEDM 300 YGTMKKMICC FSQENPERRP SRIPSTVLSR SDTGSQYIED SISQGAVCNK STS
Prostate
A150 DNA SEQUENCE Gene name: ESTs Unigene number: Hs.293616 Probeset Accession ft: AW043782
Nucleic Acid Accession ff : none found
Coding sequence: 38-1075 (underlined sequence corresponds to start and stop codon)
1 11 21 31 4 51 I AlGCAACGACG ClCGββCAGCG GlGAGCGGCGG ClCGCGCCATG TlGGCTGCTGG GGCCGCTGTG 60 CCTGCTGCTG AGCAβCCCCG CGGAGAGCCA GCTβCTCCCC GGGAACAACT TCACCAATGA 120 GTGCAACATA CCAGGCAACT TCATGTGCAG CAATGGACGG TGCATCCCGG GCGCCTGGCA 180 GTGTGACGGG CTβCCTGACT GCTTCGACAA GAβTβATGAG AAββAβTGCC CCAAGGCTAA 240 GTCGAAATGT GGCCCAACCT TCTTCCCCTG TGCCAGCGGC ATCCATTβCA TCATTββTCC 300 CTTCCGGTGC AATGGGTTTG AGGACTGTCC CGATGβCAGC GATGAAGAGA ACTGCACAGC 360 AAACCCTCTβ CTTTGCTCCA CCGCCCGCTA CCACTβCAAG AACGGCCTCT GTATTGACAA 420 GAGCTTCATC TGCGATGβAC AGAATAACTG TCAAGACAAC AGTGATGAGG AAAGCTGTGA 480 AAGTTCTCAA GAACCCββCA GTGGGCAGGT GTTTGTGACT TCAGAGAACC AACTTGTGTA 540 TTACCCCAGC ATCACCTATG CCATCATCβG CAGCTCCGTC ATTTTTGTGC TGGTGGTGGC 600 CCTGCTG6CA CTGGTCTTGC ACCACCAβCβ GAAGCGGAAC AACCTCATGA CGCTGCCCGT 660 GCACCGGCTG CAGCACCCTG TGCTGCTGTC CCGCCTGGTG GTCCTGGACC ACCCCCACCA 720 CTGCAACGTC ACCTACAACβ TCAATAATGG CATCCAGTAT GTββCCAGCC AGGCGGAGCA 780 GAATGCGTCG GAAGTAGGCT CCCCACCCTC CTACTCCGAG GCCTTGCTGG ACCAGAGGCC 840 TGCGTGGTAT GACCTTCCTC CACCGCCCTA CTCTTCTGAC ACGGAATCTC TGAACCAAGC 900 CGACCTGCCC CCCTACCGCT CCCG6TCCGG GAGTGCCAAC AGTGCCAGCT CCCAGGCAGC 960 CAGCAGCCTC CTGAβCGTGG AAβACACCAG CCACAGCCCG GββCAGCCTG βCCCCCAGGA 1020 βGGCACTGCT GAGCCCAGGG ACTCTGAGCC CAGCCAGGGC ACTGAAGAAG TATAAGTCCC 1080 AGTTATTCCA AAGTCCATAT GGGTTAATCT GCTCTGACTT GTTGCCATTC TAACAATTTG 1140 TGCTCATGGG AAGCTCTTTA AGCACCTGTA AGGATGTCTC AAGTTACAGT TTGGGATATT 1200 AACTATCTCT GCATTCCCCT CCTCCCCCAG ACTTCAGAGA TGTTTTTCTG GCGTCTCAGT 1260 TβACATGATC TGTTGTGCGT CTTTTCTGTC AGGTCACTCT TCCCTTGGGA CCCGAGATCA 1320 CACCCTCATT TTTCACATTA TTCTGTTTCT GTTCGAGAGA CAGCATATAA AACAGTATTG 1380 AAATAGβCTG GGAGAGAGCA ATGTTTCTGT GCTATATTGG ATβCTCAGAA GTβCAββAGA 1440 CGCTGGACCC AATTCTCTCT GCTGGGTAGT TACCTTATAG CATTTGGGGA TTTGGGTTAG 1500 ATGATCTAAC CAGGAGGCCA TCACTGGATG GTCACCCCCC CAAAAAAATT CCATTTGAGC 1560 ATCAAAACCT GCTTTGCACA ATCCTATTTG ATGCCCCCAG TTCAGCAGAβ TCAGTGGCCA 1620 AAGAAAACTT TGGACGTGAG TAACACCCTT CAGCAβTCGC AACGTTATTT TGGTTTTGTG 1680 AAGGACTCTG AAACCATCTA CCCTGTATAA ATTCTββCTT TAβAAATTTG CCCAAGAATG 1740 CTCATTCTGA GAGCTTTCCT CAGCACCATA TATCATCAGC CTCATCCTAA AATAGGCAGG 1800 GAGCCCCTCC CATGAGTTTA TCCAAGTTCT CAGCTCCTAA AATGCAβGCT GCCAAGACCC 1860 TACACCTGCC CTGGCTCTAC AGCCACTTAC CTββTTTCTG GACTGTCACC CTCCCAβCTG 1920 ACCTGCCCGT AGCCAAGGAA TGAGGACCTA ACTTGAβTTG GCCCAAAGTC TGACCTGGCT 1980 GTATGTCCCT GTββCCCACA CCCAGCCTGT CTTGCTCATT CATGCAGCCT CAACACTGGC 2040 CTCCAAAGTT CCCTTAACAC TTGCAAAGTC CTTTTTACCT GTGCATTTGG ACTTGAGGAC 21,00 ACTGβTTTCT ATCACAGβTG AGAGCCATGT TCAATACCTC CAGCAAβCTC TCCTGGCTCC 2160 CTGCACTGTG CACβCTCCTC TTCCCAAββT CCCAATACCA GCACCTCTAG TTAGAGTTAG 2220 GβTCAβββTC AGGCCTCTCC CAACATCCCA GTAGTTTCTC CTCTGAGACA CATGGGCAAG 2280 AβACAATTTβ GAGTCAAGAT TTTCCATTTG GATCTATTTT AAATCTTTTA GAAATGCATT 2340 TGAAACAGTβ TGTTTGTTTT TTCCCTTCTA GTTAAGGGAC TATTTATATβ TGTATAGβAA 2400 AGCTGTCTCT TTTTTTGTTT TTCCTTTAAC AAGGTCCAAA βAAAGATGCA AAAGGAGATC 2460 ACACCCTTGC CCCGCTGAGC CCCGT6ATAA CAAGTCACTC CAGACTAACC TβTβTGCCAG 2520 ACATTTGTGC ATTGTTβCAC TTTβAββTTA TTATTTATCA AGTTCTTGAA GβAAGCAGAA 2580 AβAβββACTC CTCTCTCCCT CCGTGTATAG TCTCTATGTT TGTGCTAGTT TTTCTTTTTT 2640 TTCTCTGTβT CCAβTCAGCC ACAGGGCCCG CCTCCCTGCA GGAATAAβGG GTAAAACGTT 2700 AGGTGTTGTT TGβCAAβAAA CCACACTGAC TGATGAGGGβ TAAAATGGAA CCAGGTAGAG 2760 CCACTCCGGG CAGCTGTCAC CCATTCAGAA CTTCTTTCCβ CAGCTGAAGA AATGTTCAGT 2820 AACCTβTTTG ACGCTAATTA AAACAGAGCC TGCAGGAAGT GGGGCTAAAG TGGCATTCAG 2880 TGATCCTGTT CTGTAGACTT TTCTTTCTTT TTTTAACCAA ATCCAAAGGA TGTTACAβAA 2940 AAGCTAGCCA CTGGTATTTT GTTTTGTTTA AAAAAAAAAA GAAAGAAAGA AAGAAAGAAA 3000 AACGGAAAβG AACCTAGCTG CCTGTATCTT TCATTTTTAA AATAGCACTT GAGTTATTTT 3060 CTGAβTAATC CAATAAAGAA CTTTTGATGA CAGCCAGAAT GTGTTAGAAC TCTGβCTGAA 3120 CATTTCATCT CCTGTGAGTC AGAAGGGCTT TATTTCTCCC TTTGATGGGG CCCCTTCTTC 3180 TTTCTGβTGC TCTGGAAGTT GTTTAGAGβA AAGAATTCTA ATTTTAATTA ATTGCGCAGT 3240 GAGTTAATCT CACTCGCTTT TCTGCTTCCA GGCATCTTAG GAAAAACAAA TGGTTTTAGT 3300 AGATAAGGGA TGCCTACTAA TGCTTTTTTA AAACAAACAG GGACATTTTT ATTATAβATT 3360 TGATTTTTTT AATGAATGTT TTTAAAAATA TATAAATAGβ ACACCAAAGC GGCAGβGTTT 3420 TTTTTGGGGG GAGGGGβTTT GTTTTCCAAC TCAAβATββC ACATTAGTGG CCAβCAATAT 3480 TTTTTAACTC ATTCCAACCA GβAAGCTTTT TTATACATTC CCTAAATCTA CGCCAACCAG 3540 AAAATAβTCT CATCTCTTTT TTTCTCAAAT GAGATCCGTG TTTTATTTTA GCATTAAATT 3600 AβTTACACTβ TGATGACTGG CCTATTACCT GACTCAGCTC CCTCTACCTT GAAATTGACA 3660 TTTTTAAAAA ATGCAACTAA GTββTTAATA GTGTGTGACG CTCAAACTTA ATGTAAACTG 3720 GAAAGGTTGT GTGTCGTTGC TTTTTGTβTT TTGGTTAββC TTGGTTTTβT TTTTTAATTT 3780 TTATACTTTC TAATAAATTT βCAβTTTCAT TCTTTCTβTT TGTGCAAAWG GWMCTAMARM 3840 AAMMAAAAAC AWYWTTβGGG GGGCTTGGGC CTCββAAAAA GTTTTTAACA CCACTTCGGβ 3900 TGGGGCβGCG GGGCCCACGT AGGTACGGCG ACCACGCGG6 CCCAAACGGG ACCCCAGAAG 3960 GAAACCCTGG CCAAGAAAAA GGT6GCGAGA ATTCTCCACA CCAGAAAAAA ACGCGCCGββ 4020 GGAAACCβCA GAβTGTTGCβ TAAACCACAC CCGAAGAGAG AACTCAGAAG CACACAAβCβ 4080 GGACTCAACC AGβAGGACCC AACββAACCC GATAGAGTAC G
A151 Protein sequence : βene name: ESTs Unigene number: Hs.293616 Probeset Accesεion #: AW043782 Protein Accession ff: none found Signal sequence: 1-17 Transmembrane domains : 169-191 LDLa domains : 28-66, 70-108, 112-149 Cellular Localization: plasma membrane
11 21 31 41 51
I I I I I
MWLLGPLCLL LSSAAESQLL PβNNFTNECN IPGNFMCSNG RCIPGAWQCD GLPDCFDKSD 60 EKECPKAKSK CGPTFFPCAS GIHCIIGRFR CNGFEDCPDG SDEENCTANP LLCSTARYHC 120 KNGLCIDKSF ICDGQNNCQD NSDEESCESS QEPGSGQVFV TSENQLVYYP SITYAIIGSS 180 VIFVLWALL ALVLHHQRKR NNLMTLPVHR LQHPVLLSRL WLDHPHHCN VTYNVNNGIQ 240 YVASQAEQNA SEVGSPPSYS EALLDQRPAW YDLPPPPYSS DTESLNQADL PPYRSRSGSA 300 NSASSQAASS LLSVEDTSHS PGQPGPQEGT AEPRDSEPSQ GTEEV
A152 DNA SEQUENCE Gene name: Transmembrane protease, serine 2 (TMPRSS2) Unigene number: Hs.105807 Probeset Accesεion ft: T48536 Nucleic Acid Acceεsion #: NM 005656.1
Coding sequence: 57-1535 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I
GTCATATTGA ACATTCCAGA TACCTATCAT TACTCGATGC TGTTGATAAC AGCAAGATGβ 60 CTTTGAACTC AGGβTCACCA CCAGCTATTG GACCTTACTA TGAAAACCAT GGATACCAAC 120 CGGAAAACCC CTATCCCGCA CAGCCCACTG TGGTCCCCAC TGTCTACβAG GTGCATCCGG 180 CTCAGTACTA CCCGTCCCCC GTGCCCCAGT ACGCCCCGAG GGTCCTGACβ CAGGCTTCCA 240 ACCCCGTCGT CTGCACGCAβ CCCAAATCCC CATCCGβGAC AGTGTGCACC TCAAAGACTA 300 AGAAAGCACT GTβCATCACC TTGACCCTGG GGACCTTCCT CGTGGGAGCT GCGCTββCCβ 360 CTGGCCTACT CTGGAAGTTC ATGGGCAGCA AGTGCTCCAA CTCTGGGATA GAGTGCβACT 420 CCTCAGGTAC CTGCATCAAC CCCTCTAACT GGTGTGATGβ CGTβTCACAC TGCCCCGGCG 480 GGGAGGACGA GAATCGGTGT GTTCGCCTCT ACGGACCAAA CTTCATCCTT CAGATGTACT 540 CATCTCAGAG GAAGTCCTGG CACCCTGTβT GCCAAGACGA CTGGAACGAG AACTACGGβC 600 GGGCGGCCTG CAGGGACATG GGCTATAAGA ATAATTTTTA CTCTAGCCAA GGAATAGTββ 660 ATGACAGCGG ATCCACCAGC TTTATβAAAC TGAACACAAG TGCCGGCAAT GTCGATATCT 720 ATAAAAAACT GTACCACAGT GATGCCTGTT CTTCAAAAGC AGT6GTTTCT TTACβCTβTT 780 TAGCCTGCGG GGTCAACTTG AACTCAAGCC GCCAGAβCAβ GATCGTGGGC GGTGAGAGCG 840 CGCTCCCGGG GGCCTGGCCC TGGCAGGTCA GCCTGCACGT CCAGAACGTC CACGTGTGCG 900 GAGGCTCCAT CATCACCCCC GAGTGGATCG TGACAGCCβC CCACTGCGTG GAAAAACCTC 960 TTAACAATCC ATGGCATTGG ACGGCATTTG CGGGGATTTT GAGACAATCT TTCATGTTCT 1020 ATGGAGCCGG ATACCAAGTA CAAAAAGTGA TTTCTCATCC AAATTATGAC TCCAAGACCA 1080 AβAACAATGA CATTGCGCTG ATGAAGCTGC AGAAGCCTCT GACTTTCAAC GACCTAGTβA 1140 AACCAGTβTG TCTGCCCAAC CCAGGCATGA TGCTGCAGCC AGAACAGCTC TβCTβGATTT 1200 CCβββTGGGG GGCCACCGAG GAGAAAGGGA AGACCTCAGA AGTGCTGAAC GCTGCCAAGG 1260 TGCTTCTCAT TGAβACACAβ AGATGCAACA GCAGATATGT CTATGACAAC CTβATCACAC 1320 CAGCCATGAT CTGTGCCGGC TTCCTGCAGG GGAACGTCGA TTCTTGCCAG GGTGACAGTG 1380 GAGGGCCTCT GGTCACTTCG AACAACAATA TCTGGTGGCT GATAββββAT ACAAGCTGGG 1440 GTTCTGGCTG TGCCAAAGCT TACAGACCAG GAGTβTACGG βAATGTGATβ GTATTCACGG 1500 ACTGβATTTA TCGACAAATG AAGGCAAACG GCTAATCCAC ATGGTCTTCG TCCTTGACGT 1560 CβTTTTACAA GAAAACAATG GGGCTGGTTT TGCTTCCCCG TGCATβATTT ACTCTTAGAG 1620 ATCATTCAβA GGTCACTTCA TTTTTATTAA ACAGTGAACT TGTCTGβCTT TGGCACTCTC 1680 TGCCATACTG TGCAGGCTGC AGTGGCTCCC CTGCCCAGCC TCCTCTCCCT AACCCCTTGT 1740 CCGCAAGGGβ TGATGGCCGG CTGGTTGTGG GCACTGGCGG TCAATTGTGβ AAGGAAGAGG 1800 GTTGGAGGCT GCCCCCATTG AGATCTTCCT GCTGAGTCCT TTCCAβGGGC CAATTTTGGA 1860 TGAGCATGGA GCTGTCACTT CTCAGCTGCT GGATGACTTG AGATGAAAAA GGAGAGACAT 1920 GGAAAGGGAG ACAGCCAGβT GGCACCTGCA GCGGCTβCCC TCTGGβGCCA CTTGGTAGTG 1980 TCCCCAGCCT ACTTCACAAG GGGATTTTGC TGATGGGTTC TTAGAGCCTT AGCAGCCCTG 2040 GATGGTGGCC AβAAATAAAG GGACCAGCCC TTCATβGGTβ GTGACGTβGT AGTCACTTGT 2100 AAGβGGAACA GAAACATTTT TGTTCTTATG βββTGAGAAT ATAGACAGTG CCCTTGGTGC 2160 GAβGGAAGCA ATTGAAAAGG AACTTGCCCT GAGCACTCCT GGTGCAGGTC TCCACCTGCA 2220 CATTGGGTGG GGCTCCTGGG AG6GAGACTC AβCCTTCCTC CTCATCCTCC CTGACCCTGC 2280 TCCTAGCACC CTGGAGAGTG AATGCCCCTT CβTCCCTGGC AGGGCGCCAA GTTTGGCACC 2340 ATGTCGGCCT CTTCAGGCCT GATAGTCATT GGAAATTGAG βTCCATβGGG GAAATCAAGG 2400 ATGCTCAGTT TAAGβTACAC TGTTTCCATG TTATGTTTCT ACACATTGAT GGTGGTGACC 2460 CTGAGTTCAA AGCCATCTT
A153 Protein sequence: Gene name: Transmembrane protease, serine 2 (TMPRSS2) Unigene number: Hs.105807 Probeset Accession ft: T48536 Protein Accession ft: NP_005647.1 Signal sequence: none found Transmembrane domains : 85-107 Cellular Localization: plasma membrane
1 11 21 31 41 51 1 1 I1 | 1 |1 1 1 11 MALNSGSPPA IGPYYENHGY QPENPYPAQP TWPTVYEVH PAQYYPSPVP QYAPRVLTQA 60
SNPWCTQPK SPSGTVCTSK TKKALCITLT LGTFLVGAAL AAGLLWKFMG SKCSNSGIEC 120
DSSGTCINPS NWCDβVSHCP GβEDENRCVR LYGPNFILQM YSSQRKSWHP VCQDDWNENY 180 βRAACRDMβY KNNFYSSQGI VDDSGSTSFM KLNTSAGNVD IYKKLYHSDA CSSKAWSLR 240
CLACGVNLNS SRQSRIVGGE SALPGAWPWQ VSLHVQNVHV CββSIITPEW IVTAAHCVEK 300
PLNNPWHWTA FAGILRQSFM FYGAGYQVQK VISHPNYDSK TKNNDIALMK LQKPLTFNDL 360
VKPVCLPNPG MMLQPEQLCW ISGWGATEEK GKTSEVLNAA KVLLIETQRC NSRYVYDNLI 420
TPAMICAGFL QGNVDSCQGD SGGPLVTSNN NIWWLIGDTS WβSGCAKAYR PGVYGNVMVF 480
TDWIYRQMKA NG
A154 DNA SEQUENCE
Gene name: Homo sapiens cDNA FLJ13581 fis, clone PLACE1009039
Unigene number: Hs.129179
Probeset Accession #: AI694767
Nucleic Acid Accession ft: AI694767
Coding sequence: 130-1086 (underlined sequences correspond to start and stop codons)
Figure imgf000905_0001
60
GGGGTCACAC ATTCCTTCCA TACGGTTGAG CCTCTACCTG CCTGGTGCTβ GTCACAGTTC 120
AGCTTCTTCA TGATGGTGGA TCCCAATGGC AATGAATCCA GTGCTACATA CTTCATCCTA 180
ATAGGCCTCC CTGGTTTAGA AGAGGCTCAG TTCTGβTTGG CCTTCCCATT βTβCTCCCTC 240
TACCTTATTG CTGTβCTAGG TAACTTGACA ATCATCTACA TTGTGCββAC TGAGCACAGC 300
CTGCATGAGC CCATGTATAT ATTTCTTTGC ATGCTTTCAG GCATTGACAT CCTCATCTCC 360
ACCTCATCCA TGCCCAAAAT GCTGGCCATC TTCTGGTTCA ATTCCACTAC CATCCAGTTT 420 βATβCTTβTC TGCTACAGAT GTTTGCCATC CACTCCTTAT CTGGCATGGA ATCCACAGTG 480
CTβCTβGCCA TGGCTTTTGA CCGCTATGTG GCCATCTGTC ACCCACTGCG CCATGCCACA 540
GTACTTACGT TGCCTCGTGT CACCAAAATT GβTβTGGCTβ CTGTGGTβCG GGGGGCTGCA 600
CTGATGGCAC CCCTTCCTGT CTTCATCAAG CAGCTGCCCT TCTGCCGCTC CAATATCCTT 660
TCCCATTCCT ACTGCCTACA CCAAGATGTC ATGAAGCTGG CCTGTGATGA TATCCGββTC 720
AATGTCGTCT ATGGCCTTAT CGTCATCATC TCCGCCATTG GCCTGGACTC ACTTCTCATC 780
TCCTTCTCAT ATCTβCTTAT TCTTAAGACT GTGTTGGGCT TGACACGTGA AGCCCAGGCC 840
AAGGCATTTG GCACTTGCGT CTCTCATGTG TGTGCTGTGT TCATATTCTA TGTACCTTTC 900
ATTGGATTGT CCATGGTGCA TCGCTTTAGC AAGCβGCGTβ ACTCTCCACT GCCCGTCATC 960
TTGGCCAATA TCTATCTGCT GGTTCCTCCT GTGCTCAACC CAATTGTCTA TGβAβTGAAG 1020
ACAAAGGAGA TTCGACAGCG CATCCTTCGA CTTTTCCATG TGGCCACACA CGCTTCAGAG 1080
CCCTAGGTGT CAGTGATCAA ACTTCTTTTC CATTCAGAβT CCTCTGATTC AGATTTTAAT 1140
GTTAACATTT TGGAAGACAG TATTCAGAAA AAAAATTTCC TTAATAAAAA TACAACTCAG 1200
ATCCTTCAAA TATGAAACTG GTTGGGGAAT CTCCATTTTT TCAATATTAT TTTCTTCTTT 1260
GTTTTCTTGC TACATATAAT TATTAATACC CTGACTAGGT TGTββTTβGA GGGTTATTAC 1320
TTTTCATTTT ACCATGCAGT CCAAATCTAA ACTGCTTCTA CTGATGGTTT ACAGCATTCT 1380
GAGATAAGAA TGGTACATCT AGAGAACATT TGCCAAAGGC CTAAβCACAβ CAAAGGAAAA 1440
TAAACACAGA ATATAATAAA ATGAGATAAT CTAGCTTAAA ACTATAACTT CCTCTTCAGA 1500
ACTCCCAACC ACATTGGATC TCAGAAAAAT ACTGTCTTCA AAATGACTTC TACAGAGAAG 1560
AAATAATTTT TCCTCTGGAC ACTAGCACTT AAGGGGAAGA TTGGAAβTAA AGCCTTGAAA 1620
AGAGTACATT TACCTACGTT AATGAAAGTT GACACACTβT TCTGAGAGTT TTCACAGCAT 1680
ATGGACCCTβ TTTTTCCTAT TTAATTTTCT TATCAACCCT TTAATTAGGC AAAGATATTA 1740
TTAGTACCCT CATTGTAGCC ATβββAAAAT TβATβTTCAβ TGGGGATCAG TGAATTAAAT 1800
GGGGTCATAC AAGTATAAAA ATTAAAAAAA AAAGACTTCA TGCCCAATCT CATATGATGT 1860
GGAAGAACTG TTAAAβAβAC CAACAGGGTA GTGGGTTAGA GATTTCCAGA GTCTTACATT 1920
TTCTARAGGA GGTATTTAAT TTCTTCTCAC TCATCCAGTG TTGTATTTAG GAATTTCCTβ 1980
GCAACAGAAC TCATGGCTTT AATCCCACTA βCTATTGCTT ATTGTCCTGG TCCAATTGCC 2040
AATTACCTβT GTCTTGGAAG AAGTGATTTC TAGGTTCACC ATTATGGAAG ATTCTTATTC 2100
AβAAAGTCTG CATAGGGCTT ATAGCAAGTT ATTTATTTTT AAAAGTTCCA TAGGTGTTTC 2160
TGATAG6CAG TGAGβTTAGG GAGCCACCAG TTATGATβββ AAβTATGGAA TGβCAGGTGT 2220
TGAAGATAAC ATTGGCCTTT TGAGTGTGAC TCβTAβCTGG AAAGTGAGGG AATCTTCAββ 2280 ACCATGCTTT ATTTGGβGCT TTβTGCAGTA TGGAACAβGG ACTTTGAGAC CGGGAAAGCA 2340 ATCTGACTTA GGCATGGGAA TCAGGCATTT TTGCTTCTGA GβGGCTATTA CCAAGGGTTA 2400 ATAGGTTTCA TCTTCAACAG GATATGACAA CAGTCTTAAC CAAGAAACTC AAATTACATA 2460 TACTAAAACA TGTGATCATA TATGTGGTAA βTTTCATTTT CTTTTTCAAT CCTCAGGTTC 2520 CCTGATATGG ATTCCTATNA CATGCTTTCA TCCCCTTTTG TAATGGATAT CATATTTGGA 2580 AATGCCTATT TAATACTTGT ATTTGCTβCT GGACTGTAAG CCCATGAGGG CACTGTTTAT 2640 TATTGAATGT CATCTCTGTT CATCATTGAC TGCTCTTTGC TCATCATTGA ATCCCCCAGC 2700 AAAGTGCCTA GAACATAATA GTGCTTATGC TTGACACCGG TTATTTTTCA TCAAACCTGA 2760 TTCCTTCTGT GCTβAACACA TAGCCAβGCA ATTTTCCAGC CTTCTTTGAG TTGGGTATTA 2820 TTAAATTTTA GCCATTACTT CCAATGTGAG TGGAAGTGAC ATGTGCAATT TTTATACCTG 2880 GCTCATAAAA CCCTCCCATG TGCAGCCTTT CATGTTβACA TTAAATGTGA CTTGGGAAGC 2940 TATGTGTTAC ACAβAβTTAA TTAACCNGAA AββCCTGGNA ATTTTTTGNN AANNAAACTG 3000 TGGCCNNGAG βCCCNCAACC CTTTTTNNNA ATTTGGCAAN NTCCCACTTT GTANTTTGGT 3060 AAGGAGGCCA βTTββATAAβ TGAAAAATAA AGTACTATTG TGTC
A155 PROTEIN SEQUENCE Gene name : Homo sapiens cDNA FLJ13581 fis , clone PLACE1009039 Unigene number : Hs .129179 Protein Accession ft : not available Signal sequence : none found Pfam domain : 7tm_l [43 -293] Transmembrane domains : 29-51 , 57-79 , 82-104 , 203 -225 , 239-261 , 273 -295 Cellular Localization : not determined
11 21 31 41 51
MVDPNGNESS ATYFILIGLP βLEEAQFWLA FPLCSLYLIA VLGNLTIIYI VRTEHSLHEP 60 MYIFLCMLSG IDILISTSSM PKMLAIFWFN STTIQFDACL LQMFAIHSLS GMESTVLLAM 120 AFDRYVAICH PLRHATVLTL PRVTKIβVAA WRGAALMAP LPVFIKQLPF CRSNILSHSY 180 CLHQDVMKLA CDDIRVNWY βLIVIISAIβ LDSLLISFSY LLILKTVLGL TREAQAKAFβ 240 TCVSHVCAVF IFYVPFIGLS MVHRFSKRRD SPLPVILANI YLLVPPVLNP IVYβVKTKEI 300 RQRILRLFHV ATHASEP
A156 DNA SEQUENCE βene name: vasoactive intestinal peptide receptor 1 Unigene number: Hs.198726 Probeset Accession ft: X77777 Nucleic Acid Accession ft: NM_004624.1 Coding sequence: 57-1544 (underlined sequences correspond to start and stop codons)
TCGGAGCCTG CGGAGGGTGG TGGTGGTGGT GGTGGTGGCC CTCGCCCGCC TCACTCATGC 60
CTCCTCCTCC TCTGCTCTCG CTCAGGCGCC TCGGTGGCGG TTGGTCGGCG GTTACGCGGC 120
TGGTβGTCGC GGCGGCCGGG GCTCGCTCTC GGGGAGGCCG GGGCGGATCT CGCGGCGCAG 180
GCGGCCβCβG CCGAββTGGG GTCGCGCGβC GGAGGCGGCT CGAβCTTCGT GCTGCGCβCT 240
CGCTCTTGββ CTCCTCGCTG CAβGAGGAGT GTGACTATβT GCAGATGATC GAGGTGCACC 300
ACAAGCAGTG CCTGβAGGAβ βCCCAβCTGG AGAATβAGAC AATAGGCTGC AβCAAGATβT 360
GGGACAACCT CACCTGCTβG CCAβCCACCC CTCββββCCA GGTAGTTGTC TTGGCCTGTC 420
CCCTCATCTT CAAGCTCTTC TCCTCCATTC AAGβCCGCAA TGTAAGCCGC AGCTGCACCG 480
ACGAAGGCTG GACGCACCTG βAGCCTGGCC CGTACCCCAT TGCCTGTββT TTGGATGACA 540
AGGCAGCGAG TTTGβATGAβ CAGCAGACCA TGTTCTACGG TTCTGTGAAG ACCGGCTACA 600
CCATTGGCTA CGGCCTGTCC CTCGCCACCC TTCTββTCβC CACAGCTATC CTGAGCCTGT 660
TCAGGAAGCT CCACTGCACG CGGAACTACA TCCACATGCA CCTCTTCATA TCCTTCATCC 720
TGAGGGCTGC CGCTGTCTTC ATCAAAGACT TGGCCCTCTT CGACAGCGGG GAGTCβGACC 780
AGTGCTCCGA GGGCTCGGTG GGCTGTAAGG CAGCCATGGT CTTTTTCCAA TATTGTGTCA 840
TGβCTAACTT CTTCTGGCTG CTGGTGGAGG GCCTCTACCT GTACACCCTG CTTGCCGTCT 900
CCTTCTTCTC TGAGCββAAβ TACTTCTGββ GGTACATACT CATCββCTGG GGGGTACCCA 960
GCACATTCAC CATGβTGTGG ACCATCGCCA GβATCCATTT TGAGGATTAT GGTCTCCTCA 1020
GGTGCTGGGA CACCATCAAC TCCTCACTGT βGTGGATCAT AAAGGGCCCC ATCCTCACCT 1080
CCATCTTGGT AAACTTCATC CTGTTTATTT GCATCATCCG AATCCTGCTT CAβAAACTGC 1140
GGCCCCCAβA TATCAGGAAG AGTGACAβCA GTCCATACTC AAGGCTAGCC AββTCCACAC 1200
TCCTβCTGAT CCCCCTGTTT GGAGTACACT ACATCATβTT CGCCTTCTTT CCββACAATT 1260
TTAAGCCTGA AGTGAAGATG GTCTTTGAGC TCGTCGTGGG GTCTTTCCAG βGTTTTGTGG 1320
TGGCTATCCT CTACTGCTTC CTCAATGGTβ AGGTGCAGGC GGAGCTGAβG CGGAAGTGGC 1380
GGCGCTGGCA CCTGCAGGGC GTCCTβββCT GGAACCCCAA ATACCGGCAC CCGTCβGGAG 1440
GCAGCAACGG CGCCACGTGC AGCACGCAGG TTTCCATGCT GACCCGCGTC AGCCCAβGTG 1500
CCCGCCGCTC CTCCAGCTTC CAAGCCGAAβ TCTCCCTGGT CTGACCACCA GGATCCCAβC 1560
CCAAGCGGCC CCTCCCGCCC CTTCCCACTC GCAGCAGACG CCGGGGACAG AGGCCTβCCC 1620
GββCβCGCCA GCCCCGGCCC TGGGCTCββA GGCTGCCCCC GGCCCCCTGG TCTCTGGTCC 1680
GGACACTCCT AGAGAACGCA GCCCTAGAβC CTGCCTGGAG CGTTTCTAGC AAβTβAGAGA 1740
GATβββAGCT CCTCTCCTGG AGGATβCAβG TGGAACTCAG TCATTAβACT CCTCCTCCAA 1800
AGGCCCCCTA CβCCAATCAA GGGCAAAAAG TCTACATACT TTCATCCTGA CTCTGCCCCC 1860
TGCTGGCTCT TCTβCCCAAT TGGAGGAAAG CAACCGGTGG ATCCTCAAAC AACACTGGTG 1920
TGACCTGAGβ CCACAAAGGT TCTGCCCGGG AAGGTCACCA GCACCAACAC CACGGTAGTG 1980
CCTGAAATTT CACCATTGCT GTCAAGTTCC TTTGGGTTAA GCATTACCAC TCAGGCATTT 2040
GACTGAAGAT GCAβCTCACT ACCCTATTCT CTCTTTACGC TTAGTTATCA GCTTTTTAAA 2100 βTβGGTTATT CTGβAGTTTT TGTTTGGAGA CCACACCTAT CTTAGTGGTT CCCCACCGAA 2160
GTGGACTGGC CCCTGGGTCA GTCTGGTGGβ AGGACGGTβC AACCCAAGGA CTGAGGGACT 2220
CTGAAGCCTC TGGGAAATGA GAAGGCAGCC ACCAGCGAAT GCTAGGTCTC GGACTAAGCC 2280
TACCTGCTCT CCAAGTCTCA GTGGCTTCAT CTGTCAAGTG GGACTCTGTC ACACCAGCCA 2340
TTCTTATCTC TCTGTGCTGT GGAAGCAACA GGAATCAAGA GACTGCCCTC CTTGTCCACC 2400
CACCTATGTG CCAACTGTTG TAACTAGGCT CAGAGATGTG CACCCATGGG CTCTGACAGA 2460 AAGCAGATCC TCACCCTGCT ACACATACAG GATTTβAACT CAGATCTGTC TGATAGGAAT 2520 GTGAAAGCAC GGACTCTTAC TGCTAACTTT TGTGTATCβT AACCAGCCAG ATCCTCTTGG 2580 TTATTTGTTT ACCACTTGTA TTATTAATβC CATTATCCCT GAATTCCCCT TβCCACCCCA 2640 CCCTCCCTGG AGTGTββCTβ AGGAGGCCTC CATCTCATGT ATCATCTGGA TAβGAGCCTG 2700 CTGGTCACAG CCTCCTCTβT CTGCCCTTCA CCCCAGTGGC CACTCAGCTT CCTACCCACA 2760 CCTCTGCCAG AAGATCCCCT CAGGACTGCA ACAGGCTTGT GCAACAATAA ATβTTGGCTT 2820 GGAAAAAAAA AAAA
A157 Protein sequence: Gene name- vasoactive intestinal peptide receptor 1
Unigene number: Hs 198726 Probeset Accession # : X77777 Protem Accession #: JC2195 Signal sequence : none found Transmembrane domains : 181-202, 214-236, 255-277, 290-311, 332-354, 377-399, 408-430
Cellular Localization: plasma membrane
1 11 21 31 41 51 1 1 I1 | 1 | 1 I 1 | 1 MPPPPLLSLR RLGGGWSAVT RLWAAACAR SRGGRGGSRG AGGGGRββVA RRRRLELRAA 60
RSLLβSSLQE ECDYVQMIEV QHKQCLEEAQ LENETIGCSK MWDNLTCWPA TPRGQVWLA 120
CPLIFKLFSS IQGRNVSRSC TDEβWTHLEP GPYPIACGLD DKAASLDEQQ TMFYGSVKTG 180
YTIGYGLSLA TLLVATAILS LFRKLHCTRN YIHMHLFISF ILRAAAVFIK DLALFDSGES 240
DQCSEGSVGC KAAMVFFQYC VMANFFWLLV EGLYLYTLLA VSFFSERKYF WGYILIGWGV 300
PSTFTMVWTI ARIHFEDYGL LRCWDTINSS LWWIIKGPIL TSILVNFILF ICIIRILLQK 360
LRPPDIRKSD SSPYSRLARS TLLLIPLFβV HYIMFAFFPD NFKPEVKMVF ELWGSFQβF 420
WAILYCFLN GEVQAELRRK WRRWHLQGVL GWNPKYRHPS GGSNGATCST QVSMLTRVSP 480
GARRSSSFQA EVSLV
A158 DNA SEQUENCE
Gene name: ESTs Unigene number: Hs.29383 Probeset Accession #: AW207206 Nucleic Acid Accession #: A 133619
Coding sequence: 1-2070 {underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 1 1 11 11 | 1 1 1 J 1
ATβAGCGβTβ CGGGGβTβGC GGCTGGGACG CGGCCCCCCA βCTCβCCβAC CCCβββCTCT 60
CGGCGCCGGC GCCAGCGCCC CTCTGTGGGC GTCCAβTCCT TGAGGCCGCA GAGCCCGCAG 120
CTCAGGCAGA GCGACCCGCA GAAACGGAAC CTGGACCTβG AGAAAAGCCT GCAGTTCCTG 180
CAGCAGCAGC ACTCGGAGAT GCTGGCCAAG CTCCATGAGG AGATCGAGCA TCTGAAGCGG 240
CAAAACAAGG GTGAGCCGGC GCGGGGCCCT AGGCCGGCCC TGCCTCCCCA GGCACACTCA 300
ACACTGCCGC TCCCGCAβCA CAGAAACACA GCCATCAACT CCAGCACACG CCTGGGCTCA 360
GβGGGAACAC AGGACββGGA βCCCCTCCAG ACTGTCCTTG CCCACCTGGC TGCACTGGCC 420
CCTβTATβCC AACCCAβTββ βTACAββTTC TGGGGGACCT GGACAGATGC CGCTACCTCT 480
AβCCβTββCT GGACβATβTT ATβCAGCCAA GCACAGCACG TGCTGCTCTC GβGAAGCCCA 540
GGGCCTGAGβ TCATTGCAββ βCββCAGGTG GCCACAGGGT GCTCCCCAGA CCTCCCTCCT 600
CCAAGTAGAG CTGAAATGGG AAGGAACCCC TGGGACAGCC CCTGCCCTGC TAGATCTTTG 660
CCTCAGATTG CTGCTGTGGC CAGGCCCAGG ATTTCCAGCC CTATββCTCT GAGTCCTCAC 720
ATGCTGGGββ CCCAGGGGAT ATββACACAC TCCATCCAGG GATCCCTTCC TGCCATCTGG 780
GCAGCAACCA TGGGGACAAA GGGAGβAAGC AGAβTCCTGT TTCCTTGCCA CTTβTCCAAG 840
GCACTTCCCC ATCCTGACAG CGGCCCCCAC CCAGCCCAGG ATCCTGGGCT GTGGTCTCAA 900
GCTCACTTCC CATTATCTTT GGGGCTGGGG CTGACATCAG GAGGACATCT GACTGGTGGA 960
TGGAGCCAGC CTGGβAACAT CβCAGCTGGG GCAGTGCCTA βGGCTCTCCC TTCCCAGGGA 1020
GACATGGAGA AGβGGGTTGA GGGAGGGCCC TTCCCTAGCC GCTGTGGCAA CTCCAGTGAG 1080
CTGTTCTGββ CAAAβTβTββ CCCAAβTCGG CAGCCCCAGC CCTGCAGTGC TGGGGACβCT 1140
GACAββACAC GGGAAGAGGC CATGCTTTCC CTCGGGACCT GCTGTTCCAT GTGTCCCAAG 1200
CCCTCCTGCT TTCCAGATGG CCCCTCAGGA AACCACCTTT CCAGββCCTC TβCTCCCTTβ 1260
GGCGCTCGCT GGGTCTGCAT CAACGGAGTG TGGGTAGAβC CβGGAGGACC CAGCCCTGCC 1320
AGGCTGAAGG AGGGCTCCTC ACGGACACAC AGGCCAGGAG GCAAGCGTGG GCGTCTTGCG 1380 ββCβGTAGCG CCGACACTGT GCGCTCTCCT βCAGACAGCC TCTCCATGTC AAGCTTCCAG 1440
TCTGTCAAGT CCATCTCTAA TTCAGCCAAC TCTCAAGGCA AβGCCAGGCC CCAGCCCGGC 1500
TCCTTCAACA AGCAAGATTC AAAAGCTGAC GTCTCCCAGA AGGCββACCT GβAAGAGGAG 1560
CCCCTACTTC ACAACAGCAA GCTGGACAAA GTTCCTGGGG TACAAβββCA ββCCAGAAAG 1620
GAGAAAGCAG AGGCCTCTAA TGCAGGAGCT GCCTGTATGG GGAACAGCCA βCACCAGGGC 1680
AGβCAβATGG GGGCGGGGGC ACACCCCCCA ATGATCCTGC CCCTTCCCCT βCGAAAGCCC 1740
ACCACACTTA βGCAβTβCβA A6TGCTCATC CGCGAGCTGT GGAATACCAA CCTCCTGCAG 1800
ACCCAAβAβC TβCββCACCT CAAβTCCCTC CTGGAAGGGA GCCAGAββCC CCAGGCAGCC 1860
CCGGAββAAβ CTAβCTTTCC CAβββACCAA GAAGCCACGC ATTTCCCCAA GGTCTCCACC 1920
AAGAGCCTCT CCAAGAAATG CCTGAGCCCA CCTGTGGCGG AβCβTβCCAT CCTGCCCGGA 1980
CTGAAGCAGA CCCCGAAβAA CAACTTTGCC GAGAGGCAGA AGAGβCTβCA GGCAATGCAG 2040
AAACGGCGCC TGCATCGCTC AGTGCTTTGA
A159 Protein sequence:
Gene name: ESTε
Unigene number: Hs.29383
Probeset Accession ft : AW207206
Protein Accession #: T43457
Signal sequence : none found
Transmembrane domains : 303-322
Cellular Localization: not determined MSGAGVAAGT RPPSSPTPGS RRRRQRPSVG VQSLRPQSPQ LRQSDPQKRN LDLEKSLQFL 60
QQQHSEMLAK LHEEIEHLKR ENKGEPARGP RPALPPQAHS TLPLPQHRNT AINSSTRLGS 120
GGTQDGEPLQ TVLAHLAALA PVCQPSGYRF WGTWTDAATS SRGWTMLCSQ AQHVLLSβSP 180
GPEVIAGRQV ATGCSPDLPP PSRAEMGRNP WDSPCPARSL PQIAAVARPR ISSPMALSPH 240
MLGAQGIWTH SIQGSLPAIW AATMGTKGGS RVLFPCHLSK ALPHPDSGPH PAQDPGLWSQ 300
AHFPLSLGLG LTSGGHLTGβ WSQPGNIAAG AVPRALPSQG DMEKGVEGGP FPSRCGNSSE 360
LFWAKCGPSR QPQPCSAGDA DRTREEAMLS LGTCCSMCPK PSCFPDGPSG NHLSRASAPL 420
GARWVCINGV WVEPGGPSPA RLKEGSSRTH RPGβKRGRLA GGSADTVRSP ADSLSMSSFQ 480
SVKSISNSAN SQGKARPQPβ SFNKQDSKAD VSQKADLEEE PLLHNSKLDK VPβVQβQARK 540
EKAEASNAGA ACMGNSQHQβ RQMβAβAHPP MILPLPLRKP TTLRQCEVLI RELWNTNLLQ 600
TQELRHLKSL LEβSQRPQAA PEEASFPRDQ EATHFPKVST KSLSKKCLSP PVAERAILPA 660
LKQTPKNNFA ERQKRLQAMQ KRRLHRSVL
A160 DNA SEQUENCE
Gene name : LIV-1 protein, estrogen regulated
Unigene number : Hs .79136
Probeεet Accession # : U41060
Nucleic Acid Accession # : NM_012319.2
Coding sequence : 138-2405 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
CTCGTGCCGA ATTCGβCACG AGACCGCGTG TTCGCGCCTG GTAGAβATTT CTCβAAβACA 60
CCAGTGGGCC CGTβTGGAAC CAAACCTGCG CβCGTGβCCG GGCCGTGGGA CAACGAGGCC 120
GCGGAGACGA AGGCGCAA G GCGAGGAAβT TATCTGTAAT CTTGATCCTG ACCTTTGCCC 180
TCTCTGTCAC AAATCCCCTT CATGAACTAA AAβCAGCTGC TTTCCCCCAG ACCACTGAGA 240
AAATTAGTCC βAATTβGGAA TCTGβCATTA ATGTTGACTT GGCAATTTCC ACACGGCAAT 300
ATCATCTACA ACAGCTTTTC TACCGCTATG GAGAAAATAA TTCTTTGTCA GTTGAAGGGT 360
TCAGAAAATT ACTTCAAAAT ATAGGCATAG ATAAGATTAA AAGAATCCAT ATACACCATG 420
ACCACGACCA TCACTCAGAC CACGAβCATC ACTCAGACCA TGAβCβTCAC TCAGACCATG 480
AGCATCACTC AGACCACGAG CATCACTCTG ACCATGATCA TCACTCTCAC CATAATCATG 540
CTGCTTCTGG TAAAAATAAG CGAAAAGCTC TTTGCCCAGA CCATGACTCA βATAβTTCAG 600
GTAAAGATCC TAGAAACAGC CAβGGGAAAG GAGCTCACCG ACCAGAACAT βCCAGTGβTA 660
GAAGGAATGT CAAGGACAGT GTTAGTGCTA GTGAAGTGAC CTCAACTβTβ TACAACACTβ 720
TCTCTGAAGβ AACTCACTTT CTAGAGACAA TAGAβACTCC AAβACCTGGA AAACTCTTCC 780
CCAAAGATGT AAβCAβCTCC ACTCCACCCA GTGTCACATC AAAβAβCCββ βTGAGCCGGC 840
TGGCTGβTAG GAAAACAAAT GAATCTGTGA GTGAGCCCCβ AAAAGGCTTT ATGTATTCCA 900
GAAACACAAA TGAAAATCCT CAGGAGTGTT TCAATGCATC AAAβCTACTG ACATCTCATG 960
GCATGββCAT CCAGGTTCCG CTGAATGCAA CAGAβTTCAA CTATCTCTβT CCAGCCATCA 1020
TCAACCAAAT T6ATGCTAGA TCTTGTCTGA TTCATACAAG TβAAAAGAAG GCTGAAATCC 1080
CTCCAAAGAC CTATTCATTA CAAATAGCCT GGGTTβGTGG TTTTATAGCC ATTTCCATCA 1140
TCAGTTTCCT βTCTCTGCTG GGGGTTATCT TAGTβCCTCT CATGAATCGG GTGTTTTTCA 1200
AATTTCTCCT GAGTTTCCTT GTGGCACTββ CCGTTGGGAC TTTGAGTGGT GATGCTTTTT 1260
TACACCTTCT TCCACATTCT CATGCAAβTC ACCACCATAG TCATAGCCAT GAAGAACCAG 1320
CAATGGAAAT GAAAAβAGGA CCACTTTTCA GTCATCTGTC TTCTCAAAAC ATAGAAGAAA 1380
GTGCCTATTT TGATTCCACG TGGAAGGGTC TAACAGCTCT AGGAGGCCTG TATTTCATGT 1440
TTCTTGTTGA ACATβTCCTC ACATTGATCA AACAATTTAA AGATAAGAAG AAAAAGAATC 1500
AGAAGAAACC TGAAAATGAT GATGATGTβG AGATTAAGAA GCAGTTGTCC AAGTATGAAT 1560
CTCAACTTTC AACAAATGAβ GAGAAAGTAG ATACAGATGA TCGAACTGAA GGCTATTTAC 1620
GAGCAGACTC ACAAGAGCCC TCCCACTTTG ATTCTCAGCA GCCTGCAGTC TTGGAAGAAG 1680
AAβAββTCAT βATAGCTCAT GCTCATCCAC AGGAAGTCTA CAATGAATAT GTACCCAGAG 1740
GGTGCAAGAA TAAATGCCAT TCACATTTCC ACGATACACT CGGCCAGTCA βACGATCTCA 1800
TTCACCACCA TCATβACTAC CATCATATTC TCCATCATCA CCACCACCAA AACCACCATC 1860
CTCACAGTCA CAGCCAGCGC TACTCTCGββ AGGAGCTGAA AGATGCCGGC GTCGCCACTT 1920
TGGCCTGGAT GGTGATAATG GGTβATGGCC TGCACAATTT CAGCGATGGC CTAGCAATTG 1980
GTGCTGCTTT TACTGAAββC TTATCAAβTG βTTTAAβTAC TTCTGTTGCT GTGTTCTGTC 2040
ATGAGTTGCC TCATGAATTA GGTβACTTTβ CTβTTCTACT AAAGGCTGGC ATGACCGTTA 2100
AGCAGGCTGT CCTTTATAAT GCATTGTCAβ CCATGCTGGC GTATCTTGGA ATGGCAACAG 2160
GAATTTTCAT TGGTCATTAT GCTGAAAATG TTTCTATGTG GATATTTGCA CTTACTGCTG 2220
GCTTATTCAT GTATGTTGCT CTGGTTGATA TGGTACCTGA AATGCTGCAC AATGATGCTA 2280
GTGACCATGG ATGTAGCCGC TGGGGGTATT TCTTTTTACA GAATGCTGGG ATGCTTTTGG 2340
GTTTTGGAAT TATGTTACTT ATTTCCATAT TTGAACATAA AATCGTGTTT CGTATAAATT 2400
TCTAGTTAAG GTTTAAATGC TAβAβTAβCT TAAAAAGTTG TCATAGTTTC AGTAGGTCAT 2460
AGGGAGATGA GTTTβTATGC TGTACTATβC AβCβTTTAAA GTTAGTGGGT TTTGTGATTT 2520
TTGTATTGAA TATTGCTβTC TGTTACAAAG TCAGTTAAAG GTACGTTTTA ATATTTAAGT 2580
TATTCTATCT TGGAGATAAA ATCTGTATGT GCAATTCACC GGTATTACCA GTTTATTATG 2640
TAAACAAGAG ATTTGGCATG ACATGTTCTG TATGTTTCAG GGAAAAATβT CTTTAATCCT 2700
TTTTCAAGAA CTAACACAGT TATTCCTATA CTGGATTTTA GβTCTCTβAA GAACTGCTGG 2760
TGTTTAGGAA TAAGAATGTG CATGAAGCCT AAAATACCAA GAAAβCTTAT ACTGAATTTA 2820
AGCAAAGAAA TAAAGGAGAA AAGAGAAGAA TCTGAGAATT GGGGAGGCAT AGATTCTTAT 2880
AAAAATCACA AAATTTGTTG TAAATTAGAG GGGAGAAATT TAGAATTAAG TATAAAAAGG 2940
CAGAATTAGT ATAGAGTACA TTCATTAAAC ATTTTTGTCA βGATTATTTC CCGTAAAAAC 3000
GTAGTβAβCA CTCTCATATA CTAATTAβTβ TACATTTAAC TTTGTATAAT ACAGAAATCT 3060
AAATATATTT AATGAATTCA AGCAATATAC ACTTGACCAA GAAATTGβAA TTTCAAAATG 3120
TTCGTGCGGG TTATATACCA GATGAGTACA GTGAGTAGTT TATGTATCAC CAGACTGGGT 3180
TATTGCCAAG TTATATATCA CCAAAAGCTG TATGACTGβA TGTTCTGGTT ACCTGβTTTA 3240
CAAAATTATC AβAGTAGTAA AACTTTGATA TATATGAGGA TATTAAAACT ACACTAAGTA 3300
TCATTTGATT CGATTCAGAA AGTACTTTGA TATCTCTCAG TGCTTCAGTβ CTATCATTβT 3360 GAGCAATTGT CTTTATATAC GGTACTGTAG CCATACTAGG CCTGTCTGTG GCATTCTCTA GATGTTTCTT TTTTACACAA TAAATTCCTT ATATCAGCTT G
A161 PROTEIN SEQUENCE Gene name: LIV-1 protein, estrogen regulated Unigene number: Hs.79136 Protein Accession ft: NP_036451 Signal sequence : 1-21 Pfam domain: Zip [591-743] Transmembrane domains: 330-346, 352-368 , 427-444 , 663-679, 688-703 , 730-745 Cellular Localization: plasma membrane
1 11 21 31 41 51 1 1 | 1 1 1 11 11 | 1 MARKLSVILI LTFALSVTNP LHELKAAAFP QTTEKISPNW ESGINVDLAI STRQYHLQQL 60
FYRYGENNSL SVEGFRKLLQ NIGIDKIKRI HIHHDHDHHS DHEHHSDHER HSDHEHHSDH 120
EHHSDHDHHS HHNHAASGKN KRKALCPDHD SDSSGKDPRN SQGKGAHRPE HASβRRNVKD 180
SVSASEVTST VYNTVSEGTH FLETIETPRP GKLFPKDVSS STPPSVTSKS RVSRLAGRKT 240
NESVSEPRKG FMYSRNTNEN PQECFNASKL LTSHGMβlQV PLNATEFNYL CPAIINQIDA 300
RSCLIHTSEK KAEIPPKTYS LQIAWVββFI AISIISFLSL LβVILVPLMN RVFFKFLLSF 360
LVALAVGTLS GDAFLHLLPH SHASHHHSHS HEEPAMEMKR βPLFSHLSSQ NIEESAYFDS 420
TWKGLTALGG LYFMFLVEHV LTLIKQFKDK KKKNQKKPEN DDDVEIKKQL SKYESQLSTN 480
EEKVDTDDRT EβYLRADSQE PSHFDSQQPA VLEEEEVMIA HAHPQEVYNE YVPRGCKNKC 540
HSHFHDTLβQ SDDLIHHHHD YHHILHHHHH QNHHPHSHSQ RYSREELKDA GVATLAWMVI 600
MGDGLHNFSD GLAIGAAFTE βLSSβLSTSV AVFCHELPHE LGDFAVLLKA GMTVKQAVLY 660
NALSAMLAYL GMATGIFIβH YAENVSM IF ALTAGLFMYV ALVDMVPEML HNDASDHGCS 720
RWGYFFLQNA GMLLGFGIML LISIFEHKIV FRINF
A162 DNA si - uence βene name: bone morphogenetic protein receptor IB (ALK-6) Unigene number: Hs.87223 Probeset Accession ft: AA250737 Nucleic Acid Accesεion ft: NM_001203 Coding sequence: 274-1782 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I cβcββeecec GGAGTCGGCG GGGCCTCGCβ GGACGCGβGC AGTβCββAβA CCGCGβCβCT 60 βAGGACGCGG GAGCCGGGAG CGCACGCGCβ βββTββAβTT CAGCCTACTC TTTCTTAβAT 120 GTGAAAGGAA ACβAAβATCA TTTCATGCCT TGTTGATAAA GGTTCAGACT TCTGCTGATT 180 CATAACCATT TββCTCTβAG CTATGACAAG AGAGGAAACA AAAAGTTAAA CTTACAAGCC 240 TGCCATAAGT GAGAAGCAAA CTTCCTTGAT AACATGCTTT TGCGAAGTGC AGGAAAATTA 300 AATGTGGGCA CCAAGAAAGA GGATGGTGAG AGTACAGCCC CCACCCCCCG TCCAAAGGTC 360 TTGCGTTGTA AATGCCACCA CCATTGTCCA GAAGACTCAG TCAACAATAT TTGCAGCACA 420 GACGGATATT GTTTCACGAT GATAGAAGAG GATGACTCTG GGTTGCCTGT GGTCACTTCT 480 GGTTβCCTAG GACTAGAAGG CTCAGATTTT CAGTGTCGGG ACACTCCCAT TCCTCATCAA 540 AGAAGATCAA TTGAATGCTβ CACAGAAAGβ AACGAATGTA ATAAAGACCT ACACCCTACA 600 CTGCCTCCAT TGAAAAACAG AβATTTTβTT GATGGACCTA TACACCACAG GGCTTTACTT 660 ATATCTGTGA CTGTCTGTAG TTTβCTCTTG GTCCTTATCA TATTATTTTG TTACTTCCGG 720 TATAAAAGAC AAGAAACCAG ACCTCGATAC AGCATTGββT TAGAACAGβA TGAAACTTAC 780 ATTCCTCCTG GAGAATCCCT GAGAGACTTA ATTGAGCAGT CTCAGAGCTC AGβAAGTGβA 840 TCAGGCCTCC CTCTGCTGGT CCAAAGGACT ATAGCTAAGC AGATTCAGAT GGTβAAACAG 900 ATTGGAAAAG GTCGCTATGG GGAAGTTTGG ATGGGAAAβT GGCGTGGCGA AAAGGTAGCT 960 GTGAAAGTGT TCTTCACCAC AGAGGAAGCC AGCTGGTTCA GAGAGACAGA AATATATCAG 1020 ACAGTGTTβA TGAGGCATGA AAACATTTTG GGTTTCATTG CTGCAGATAT CAAAβGGACA 1080 GGGTCCTGGA CCCAβTTβTA CCTAATCACA GACTATCATG AAAATGGTTC CCTTTATGAT 1140 TATCTGAAGT CCACCACCCT AGACGCTAAA TCAATGCTGA AβTTAGCCTA CTCTTCTGTC 1200 AGTGGCTTAT βTCATTTACA CACAβAAATC TTTAβTACTC AAGGCAAACC AGCAATTGCC 1260 CATCGAGATC TGAAAAGTAA AAACATTCTG GTGAAGAAAA ATGGAACTTG CTGTATTGCT 1320 GACCTGGGCC TGGCTGTTAA ATTTATTAGT βATACAAATβ AAGTTGACAT ACCACCTAAC 1380 ACTCGAGTTβ GCACCAAACG CTATATGCCT CCAGAAGTGT TββACβAβAβ CTTGAACAGA 1440 AATCACTTCC AGTCTTACAT CATGGCTGAC ATGTATAGTT TTββCCTCAT CCTTTGGGAG 1500 GTTGCTAGGA GATGTβTATC AGGAGGTATA GTGGAAGAAT ACCAGCTTCC TTATCATGAC 1560 CTAGTGCCCA GTGACCCCTC TTATGAβGAC ATGAGGGAGA TTGTGTGCAT CAAGAAGTTA 1620 CGCCCCTCAT TCCCAAACCβ GTGGAGCAGT GATGAGTGTC TAAGGCAGAT GββAAAACTC 1680 ATGACAGAAT GCTGGGCTCA CAATCCTGCA TCAAGGCTGA CAGCCCTGCG GGTTAAGAAA 1740 ACACTTGCCA AAATGTCAGA GTCCCAGGAC ATTAAACTCT GATAGGAGAG GAAAAGTAAβ 1800 CATCTCTGCA GAAAGCCAAC AGGTACTCTT CTGTTTGTGG GCAGAGCAAA AβACATCAAA 1860 TAAGCATCCA CAGTACAAGC CTTGAACATC GTCCTGCTTC CCAGTGGGTT CAGACCTCAC 1920 CTTTCAGGGA GCGACCTGGG CAAAGACACA GAAGCTCCCA GAAGβAβAGA TTGATCCGTG 1980 TCTGTTTGTA GGCGGAGAAA CCGTTGββTA ACTTGTTCAA GATATGATβC AT
A163 Protein sequence Gene name: bone morphogenetic protein receptor IB (ALK-6) Unigene number: Hs .72472 / Hs .87223 Probeset Accession #: AA250737 / U89326 Protein Accession ft: NP_001194 Signal sequence: 1-13 Transmembrane domains: 128-144 PFAM domains : activin_receptor [30-111] , protein kinase [204-491] Cellular Localization: plasma membrane 11 21 31 41 51
I I I I I
MLLRSAGKLN VGTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD G 1YCFTMIEED 60 DSGLPWTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD 120 βPIHHRALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPGESLRDLI 180 EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GKWRβEKVAV KVFFTTEEAS 240 WFRETEIYQT VLMRHENILG FIAADIKβTG SWTQLYLITD YHENGSLYDY LKSTTLDAKS 300 MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360 TNEVDIPPNT RVGTKRYMPP EVLDESLNRN HFQSYIMADM YSFGLILWEV ARRCVSGGIV 420 EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMGKLM TECWAHNPAS 480 RLTALRVKKT LAKMSESQDI KL
A164 DNA sequence
Gene name: ESTs Unigene number: HS.157601 Probeset Accession ft: W07459 Nucleic Acid Accession AC005383 Coding Sequence : 328-2751 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
GACAGTGTTC GCGGCTGCAC CGCTCββAGG CTGGβTGACC CGCGTAGAAG TβAAβTACTT 60
TTTTATTTGC AGACCTGGGC CGATGCCβCT TTAAAAAACG CGAββββCTC TATGCACCTC 120
CCTGGCGGTA GTTCCTCCGA CCTCAGCCGG GTCGGGTCGT GCCGCCCTCT CCCAGGAGAG 180
ACAAACAGGT GTCCCACGTG GCAGCCGCGC CCCGGGCGCC CCTCCTGTGA TCCCGTAGCG 240
CCCCCTGGCC CGAGCCβCβC CCGGGTCTGT GAGTAGAGCC GCCCGGGCAC CGAGCGCTGG 300
TCGCCβCTCT CCTTCCβTTA TATCAACATG CCCCCTTTCC TGTTGCTGGA GGCCGTCTGT 360
GTTTTCCTGT TTTCCAGAβT βCCCCCATCT CTCCCTCTCC AGβAAGTCCA TGTAAGCAAA 420
GAAACCATCβ ββAAβATTTC AGCTGCCAGC AAAATGATGT GGTGCTCGGC TGCAGTGGAC 480
ATCATGTTTC TGTTAGATGG GTCTAACAGC GTCGGGAAAG GGAGCTTTGA AAGGTCCAAG 540
CACTTTGCCA TCACAGTCTG TGACGGTCTG GACATCAGCC CCGAGAGGGT CAGAGTGGGA 600
GCATTCCAGT TCA6TTCCAC TCCTCATCTG GAATTCCCCT TGGATTCATT TTCAACCCAA 660
CAGGAAGTGA AGβCAAβAAT CAAGAGGATG GTTTTCAAAG GAGGGCGCAC GGAGACGGAA 720
CTTGCTCTGA AATACCTTCT GCACAGAGGG TTGCCTGGAG GCAGAAATGC TTCTGTGCCC 780
CAGATCCTCA TCATCβTCAC TGATGGGAAG TCCCAGGGGG ATGTGGCACT GCCATCCAAG 840
CAGCTGAAGG AAAGGGGTGT CACTGTGTTT GCTGTGGGGG TCAGGTTTCC CAGGTGGGAG 900
GAGCTGCATG CACTGGCCAG CGAGCCTAGA GGGCAGCACG TGCTGTTGGC TGAGCAGGTG 960 βAβGATGCCA CCAACGGCCT CTTCAGCACC CTCAGCAGCT CGGCCATCTG CTCCAGCGCC 1020
ACβCCAGACT GCA6GGTCGA GGCTCACCCC TGTGAGCACA GGACGCTGGA GATGGTCCGG 1080
GAGTTCGCTβ GCAATGCCCC ATGCTGGAGA GGATCGCGGC GGACCCTTGC GGTβCTββCT 1140
CCACACTβTC CCTTCTACAG CTββAAβAGA GTGTTCCTAA CCCACCCTβC CACCTGCTAC 1200
AGGACCACCT GCCCAGGCCC CTGTβACTCG CAGCCCTβCC AβAATGGAGG CACATGTβTT 1260
CCAGAAGGAC TGGACGGCTA CCAGTGCCTC TGCCCGCTGG CCTTTββAβG GβAββCTAAC 1320
TGTGCCCTGA AGCTGAGCCT GGAATβCAGβ GTCGACCTCC TCTTCCTGCT GβACAβCTCT 1380
GCGGGCACCA CTCTGGACGG CTTCCTGCGG βCCAAAβTCT TCGTGAAβCβ βTTTβTβCGG 1440
GCCGTβCTGA GCβAβGACTC TCGββCCCGA βTββGTGTGG CCACATACAG CAGGGAGCTG 1500
CTGGTββCGG TGCCTGTGGG GGAGTACCAG GATGTGCCTG ACCTGGTCTG GAGCCTCGAT 1560
GGCATTCCCT TCCGTGGTGG CCCCACCCTG ACGGGCAGTG CCTTGCGGCA GGCGGCAGAG 1620
CGTGGCTTCG GGAGCβCCAC CAGGACAGGC CAGGACCGGC CACGTAGAGT GGTGGTTTTG 1680
CTCACTGAGT CACACTCCGA GGATGAGGTT GCGGGCCCAG CGCGTCACGC AAGGGCGCGA 1740
GAGCTGCTCC TGCTGGGTGT AGGCAGTβAβ GCCGTGCGGG CAGAGCTGGA GβAβATCACA 1800
GGCAGCCCAA AβCATGTGAT GGTCTACTCG GATCCTCAGG ATCTGTTCAA CCAAATCCCT 1860
GAGCTGCAGG GGAAGCTGTG CAGCCGGCAG CGGCCAGGGT GCCGGACACA AGCCCTGGAC 1920
CTCGTCTTCA TGTTββACAC CTCTGCCTCA GTAGGGCCCG AGAATTTTGC TCAGATGCAG 1980
AGCTTTGTGA GAAGCTβTGC CCTCCAGTTT GAGGTGAACC CTGAC6TGAC ACAGGTCGGC 2040
CTGGTGGTGT ATGGCAGCCA GβTβCAβACT βCCTTCβGGC TβGACACCAA ACCCACCCGG 2100
GCTGCGATGC TGCGGGCCAT TAGCCAGGCC CCCTACCTAG GTGGGGTGGG CTCAGCCβGC 2160
ACCGCCCTGC TGCACATCTA TGACAAAGTG ATGACCGTCC AGAGGGGTGC CCGGCCTGGT 2220
GTCCCCAAAG CTGTGGTGGT GCTCACAGGC GGGAGAGGCG CAGAGGATGC AGCCGTTCCT 2280
GCCCAGAAGC TGAGGAACAA TGGCATCTCT GTCTTGGTCG TGGGCGTGGG GCCTGTCCTA 2340
AGTGAGGGTC TGCGGAGβCT TGCAGGTCCC CGGGATTCCC TGATCCACGT GGCAβCTTAC 2400
GCCGACCTGC GGTACCACCA GβACβTβCTC ATTGAGTGGC TGTGTGGAGA AGCCAAGCAG 2460
CCAGTCAACC TCTGCAAACC CAGCCCGTGC ATGAATGAGG GCAGCTGCGT CCTGCAGAAT 2520
GGGAGCTACC GCTGCAAGTG TCGGGATGGC TβGGAGGGCC CCCACTGCGA GAACCGTGAG 2580
TGGAGCTCTT GCTCTGTATG TGTβAGCCAG GGATGGATTC TTGAGACGCC CCTGAGGCAC 2640
ATGGCTCCCG TGCAGGAβGG CAβCAGCCGT ACCCCTCCCA GCAACTACAG AGAAGGCCTG 2700
GGCACTGAAA TGGTGCCTAC CTTCTGGAAT GTCTGTGCCC CAGGTCCTTA GAATGTCTGC 2760
TTCCCGCCGT ββCCAGGACC ACTATTCTCA CTGAGGGAGG AGGATGTCCC AACTGCAGCC 2820
ATGCTβCTTA GAGACAAGAA AGCAGCTGAT GTCACCCACA AACGATGTTG TTGAAAAGTT 2880
TTGATGTGTA AGTAAATACC CACTTTCTGT ACCTGCTGTβ CCTTGTTGAG GCTATGTCAT 2940
CTGCCACCTT TCCCTTGAGG ATAAACAAGG GGTCCTGAAG ACTTAAATTT AGCGGCCTβA 3000
CGTTCCTTTG CACACAATCA ATGCTCGCCA GAATGTTGTT GACACAβTAA TβCCCAGCAG 3060
AGGCCTTTAC TAGAGCATCC TTTGβACβGC GAAGGCCACG GCCTTTCAAG ATGGAAAGCA 3120
GCAβCTTTTC CACTTCCCCA CAGACATTCT GGATGCATTT GCATTGAGTC TβAAAGGGGG 3180
CTTGAGGGAC GTTTGTGACT TCTTGGCGAC TGCCTTTTGT GTβTGGAAGA GACTTGGAAA 3240
GGTCTCAβAC TGAATGTGAC CAATTAACCA GCTTGGTTGA TGATGGGGGA GGGGCTGA6T 3300
TGTGCATGGG CCCAGGTCTG GAGGGCCACG TAAAATCβTT CTGAGTCβTβ AGCAGTGTCC 3360 ACCTTβAAGG TCTTC A165 Protein sequence
Gene name: ESTS
Unigene number: Hε.157601
Protein Accession ft: none found
Signal sequence : 1-17
Transmembrane domains : none found
VGW domains : 49-223; 341-518; 529-706
EGF domains : 298-333 ; 715-748
Cellular Localization: εecreted
60
Figure imgf000911_0001
120
MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180
FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240
PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300
SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL 360
RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT 420
LTGSALRQAA ERGFGSATRT GQDRPRRW LLTESHSEDE VAGPARHARA RELLLLGVβS 480
EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540
SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600
APYLCβVβSA βTALLHIYDK VMTVQRGARP GVPKAVWLT GβRβAEDAAV PAQKLRNNGI 660
SVLWGVGPV LSEβLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCβEAK QPVNLCKPSP 720
CMNEGSCVLQ NβSYRCKCRD GWEGPHCENR EWSSCSVCVS QβWILETPLR HMAPVQEGSS 780
RTPPSNYREβ LβTEMVPTFW NVCAPGP
A166 DNA εequence
Gene name: Homo sapiens beta-1 adrenergic receptor mRNA, 3' UTR Unigene number: Hs.37744 Probeset Accession ft: AA011176 Nucleic Acid Accession #: AF272890 Coding Sequence: 87-1520 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I
TGCTACCCβC GCCCGG CTT CTGGGGTGTT CCCCAACCAC GGCCCAβCCC TGCCACACCC 60 CCCGCCCCCG GCCTCCβCAG CTCGGCATGG GCCCββGGβT GCTCβTCCTβ GGCGCCTCCG 120 AGCCCGGTAA CCTGTCβTCG GCCGCACCGC TCCCCGACββ CCCββCCACC GCββCβCCGC 180 TGCTGGTGCC CGCGTCGCCG CCCGCCTCGT TGCTGCCTCC CGCCAGCGAA AGCCCCGAGC 240 CGCTGTCTCA GCAGTGGACA GCGGGCATGG GTCTGCTGAT GGCGCTCATC GTGCTGCTCA 300 TCGTGGCGGG CAATGTGCTG GTGATCGTGG CCATCGCCAA GACGCCGCGG CTGCAGACGC 360 TCACCAACCT CTTCATCATG TCCCTGGCCA GCGCCGACCT GGTCATGGGG CTGCTGGTGG 420 TGCCβTTCββ GGCCACCATC GTGGTGTGGG GCCGCTGGGA GTACGGCTCC TTCTTCTGCβ 480 AGCTGTGβAC CTCAGTGGAC GTGCTGTGCG TGACGGCCAG CATCGAGACC CTβTGTβTCA 540 TTGCCCTGGA CCGCTACCTC GCCATCACCT CGCCCTTCCG CTACCAGAGC CTβCTβACGC 600 GCGCGCGGGC βCGGGGCCTC GTGTGCACCG TβTβGGCCAT CTCGGCCCTβ GTGTCCTTCC 660 TGCCCATCCT CATGCACTβG TGβCGGGCββ AGAβCβACβA GGCGCβCCβC TGCTACAACG 720 ACCCCAAGTG CTGCGACTTC GTCACCAACC GGGCCTACβC CATCβCCTCG TCCGTAGTCT 780 CCTTCTACGT GCCCCTGTGC ATCATGGCCT TCGTGTACCT GCGGGTGTTC CGCGAGGCCC 840 AGAAGCAGGT GAAGAAGATC GACAGCTGCG AGCβCCGTTT CCTCGGCGGC CCAGCGCββC 900 CGCCCTCGCC CTCGCCCTCG CCCGTCCCCβ CGCCCGCGCC GCCβCCCGGA CCCCCGCGCC 960 CCGCCGCCGC CGCCGCCACC GCCCCβCTGG CCAACGGGCG TGCGββTAAG CGGCGGCCCT 1020 CGCGCCTCGT GGCCCTACGC GAGCAGAAGG CGCTCAAGAC GCTGGGCATC ATCATGGGCG 1080 TCTTCACGCT CTGCTGGCTG CCCTTCTTCC TGGCCAACGT GGTGAAGGCC TTCCACCGCG 1140 AGCTGGTβCC CGACCGCCTC TTCGTCTTCT TCAACTGGCT GGGCTACGCC AACTCGGCCT 1200 TCAACCCCAT CATCTACTGC CGCAGCCCCG ACTTCCGCAA GGCCTTCCAβ GβACTβCTCT 1260 GCTGCGCGCG CAGGGCTGCC CβCCββCGCC ACβCβACCCA CββAGACCGβ CCGCGCGCCT 1320 CGGGCTGTCT GGCCCGGCCC GGACCCCCGC CATCβCCCGβ ββCCβCCTCG GACGACGACG 1380 ACGACGATGT CGTCGGGGCC ACGCCGCCCG CGCGCCTGCT GGAGCCCTGG GCCGGCTGCA 1440 ACGGCGGGGC GGCGGCGGAC AGCGACTCGA GCCTGGACGA GCCGTGCCGC CCCGGCTTCG 1500 CCTCGGAATC CAAGβTGTAβ GGCCCββCβC GGβGCGCGGA CTCCβββCAC GGCTTCCCAβ 1560 GGGAACGAGG AGATCTGTGT TTACTTAAGA CCβATAβCAβ GTGAACTCβA AGCCCACAAT 1620 CCTCGTCTGA ATCATCCβAβ GCAAAGAGAA AAGCCACGβA CCGTTGCACA AAAAGGAAAG 1680 TTTGGGAAGG GATGQ3AGAG TGGCTTGCTG ATβTTCCTTβ TTG
A167 Protein sequence Gene name: Homo sapiens beta-1 adrenergic receptor mRNA, 3 ' UTR Unigene number: HS.37744 Protein Accession ft : AA011176 Signal sequence : none found Transmembrane domains: 62-84, 95-117, 135-157, 177-198, 226-248 Pfam domian: 7tm_l [75-377] Cellular Localization: plasma membrane
41 51
I
MGAGVLVLGA SEPGNLSSAA PLPDGAATAA RLLVPASPPA SLLPPASESP EPLSQQWTAG 60 MGLLMALIV LIVAGNVLVI VAIAKTPRLQ TLTNLFIMSL ASADLVMGLL WPFGATIW 120 WGRWEYGSFF CELWTSVDVL CVTASIETLC VIALDRYLAI TSPFRYQSLL TRARARGLVC 180
TVWAISALVS FLPILMHWWR AESDEARRCY NDPKCCDFVT NRAYAIASSV VSFYVPLCIM 240
AFVYLRVFRE AQKQVKKIDS CERRFLGGPA RPPSPSPSPV PAPAPPPGPP RPAAAAATAP 300
LANGRAGKRR PSRLVALREQ KALKTLGIIM GVFTLCWLPF FLANWKAFH RELVPDRLFV 360
FFNWLGYANS AFNPII CRS PDFRKAFQGL LCCARRAARR RHATHGDRPR ASGCLARPGP 420 PPSPGAASDD DDDDWGATP PARLLEPWAG CNGGAAADSD SSLDEPCRPG FASESKV
A168 DNA sequence Gene name: CEGP1 Unigene number: Hs.222399 Probeset Accession it : AA256485 Nucleic Acid Accession it: AJ400877 Coding sequence: 81-3080 (underlined sequences correspond to start and stop codons)
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GGCGTCCGCG CACACCTCCC CGCGCCGCCG CCβCCACCGC CCGCACTCCG CCβCCTCTGC 60 CCGCAACCGC TGAGCCATCC ATGGGGGTCG CGGβCCGCAA CCGTCCCGGG GCGGCCTGGG 120 CGGTGCTGCT GCTGCTGCTG CTβCTGCCGC CACTGCTβCT GCTGGCββGG GCCGTCCCGC 180 CGGGTCGGGG CCGTGCCGCG βGGCCGCAGG AGGATGTAGA TGAβTGTGCC CAAGGGCTAG 240 ATGACTGCCA TGCCGACGCC CTGTβTCAGA ACACACCCAC CTCCTACAAG TβCTCCTGCA 300 AGCCTGGCTA CCAAGGGGAA GGCAGβCAGT GTGAGGACAT CGATGAATGT ββAAATGAGC 360 TCAATGβAβG CTGTGTCCAT GACTGTTTβA ATATTCCAGG CAATTATCGT TGCACTTGTT 420 TTGATββCTT CATGTTβGCT CATGACGGTC ATAATTGTCT TGATGTGGAC GAGTGCCTGG 480 AGAACAATGG CGGCTGCCAG CATACCTGTβ TCAACGTCAT GGGGAGCTAT GAGTGCTGCT 540 GCAAGGAβββ GTTTTTCCTG AGTGACAATC AGCACACCTG CATTCACCGC TCGGAAGAGG 600 GCCTGAGCTG CATGAATAAβ βATCACGGCT GTAGTCACAT CTCCAAββAβ GCCCCAAGGG 660 GCAGCGTCGC CTGTβAGTGC AGGCCTGGTT TTGAGCTGGC CAAGAACCAβ AGAGACTGCA 720 TCTTGACCTG TAACCATGGG AACGGTGGGT GCCAGCACTC CTβTβACGAT ACAGCCGATG 780 GCCCAGAGTG CAGCTGCCAT CCACAGTACA AGATGCACAC AGATGGGAβG AβCTGCCTTβ 840 AβCβAGAGβA CACTGTCCTG βAββTGACAG AGAβCAACAC CACATCAβTG GTGGATGGGG 900 ATAAACGGβT βAAACGGCGG CTCCTCATGG AAACGTGTβC TβTCAACAAT GGAGGCTGTG 960 ACCGCACCTG TAAGGATACT TCGACAGGTG TCCACTGCAG TTβTCCTGTT GGATTCACTC 1020 TCCAGTTGGA TGβGAAGACA TGTAAAβATA TTGATGAGTβ CCAGACCCGC AATGGAGGTT 1080 GTGATCATTT CTGCAAAAAC ATCGTβββCA GTTTTGACTG CGGCTGCAAG AAAGGATTTA 1140 AATTATTAAC AGATGAGAAG TCTTGCCAAG ATGTGGATGA GTβCTCTTTβ βATAGGACCT 1200 GTGACCACAG CTGCATCAAC CACCCTGGCA CATTTGCTTβ TβCTTβCAAC CGAGGGTACA 1260 CCCTGTATGG CTTCACCCAC TGTGGAGACA CCAATGAGTβ CAβCATCAAC AACβGAGGCT 1320 GTCAGCAGGT CTGTGTGAAC ACAGTGGGCA GCTATGAATG CCAβTβCCAC CCTGGGTACA 1380 AGCTCCACTβ βAATAAAAAA βACTGTGTGG AAGTβAAGGG GCTCCTβCCC ACAAGTGTGT 1440 CACCCCGTGT GTCCCTGCAC TGCGGTAAGA GTGβTββAββ AβACGGGTGC TTCCTCAGAT 1500 GTCACTCTGG CATTCACCTC TCTTCAGATG TCACCACCAT CAGGACAAβT βTAACCTTTA 1560 AβCTAAATβA AGGCAAGTGT AGTTTGAAAA ATGCTGAGCT GTTTCCCGAG GβTCTβCGAC 1620 CAGCACTACC AGAGAAGCAC AGCTCAGTAA AAGAGAGCTT CCGCTACGTA AACCTTACAT 1680 βCAGCTCTGβ CAAGCAAGTC CCAGGAGCCC CTGGCCGACC AAGCACCCCT AAGβAAATGT 1740 TTATCACTGT TGAGTTTGAβ CTTGAAACTA ACCAAAAGGA GGTGACAGCT TCTTGTGACC 1800 TβAβCTGCAT CGTAAAGCGA ACCGAGAAGC GGCTCCGTAA AGCCATCCGC ACGCTCAGAA 1860 AββCCβTCCA CA6GGAGCAG TTTCACCTCC AGCTCTCAGG CATGAACCTC GACGTGGCTA 1920 AAAAβCCTCC CAGAACATCT GAACGCCAGG CAGAβTCCTG TGGAGTGGGC CAGGGTCATG 1980 CAGAAAACCA ATGTβTCAβT TβCAGGGCTG GGACCTATTA TGATβGAGCA CGAGAACGCT 2040 GCATTTTATG TCCAAATGGA ACCTTCCAAA ATGAGGAAGβ ACAAATGACT TGTβAACCAT 2100 GCCCAAGACC AGGAAATTCT GGGGCCCTGA AGACCCCAGA AGCTTβGAAT ATGTCTGAAT 2160 GTGGAGGTCT GTGTCAACCT GGTGAATATT CTGCAGATGG CTTTGCACCT TGCCAGCTCT 2220 GTGCCCTGGβ CACGTTCCAG CCTGAAGCTG βTCGAACTTC CTGCTTCCCC TGTGGAβGAG 2280 GCCTTGCCAC CAAACATCAG GGAGCTACTT CCTTTCAGGA CTGTGAAACC AGAGTTCAAT 2340 GTTCACCTGG ACATTTCTAC AACACCACCA CTCACCGATG TATTCβTTβC CCAGT6GGAA 2400 CATACCAGCC TGAATTTGGA AAAAATAATT GTGTTTCTTβ CCCAGGAAAT ACTACGACTG 2460 ACTTTGATGG CTCCACAAAC ATAACCCAGT GTAAAAACAG AAGATGTGGA GGGGAGCTGβ 2520 GAGATTTCAC TβGGTACATT βAATCCCCAA ACTACCCAGG CAATTACCCA GCCAACACCG 2580 AGTGTACGTG GACCATCAAC CCACCCCCCA AGCGCCGCAT CCTβATCβTG GTCCCTGAGA 2640 TCTTCCTGCC CATAGAGGAC GACTGTGGGG ACTATCTG T GATGCβGAAA ACCTCTTCAT 2700 CCAATTCTGT GACAACATAT GAAACCTGCC AGACCTACGA ACGCCCCATC βCCTTCACCT 2760 CCAGGTCAAA GAAGCTGTβG ATTCAGTTCA AGTCCAATGA AGGGAACAGC GCTAGAβββT 2820 TCCAGCTCCC ATACGTGACA TATGATGAGG ACTACCAGGA ACTCATTGAA GACATAGTTC 2880 GAGATGGCAG GCTCTATGCA TCTGAGAACC ATCAGGAAAT ACTTAAGGAT AAGAAACTTA 2940 TCAAGGCTCT GTTTGATGTC CTGGCCCATC CCCAGAACTA TTTCAAGTAC ACAGCCCAGG 3000 AGTCCCβAGA GATGTTTCCA AGATCGTTCA TCCGATTGCT ACGTTCCAAA GTGTCCAGGT 3060 TTTTGAGACC TTACAAATGA CTCAGCCCAC GTβCCACTCA ATACAAATGT TCTGCTATAG 3120 βGTTGGTGGG ACAβAβCTGT CTTCCTTCTG CATGTCAGCA CAGTCGGGTA TTGCTGCCTC 3180 CCGTATCAGT GACTCATTAG AGTTCAATTT TTATAβATAA TACAGATATT TTGGTAAATT 3240 GAACTTGGTT TTTCTTTCCC AGCATCGTGG ATGTAGACTG AGAATGGCTT TGAGTGGCAT 3300 CAGCTTCTCA CTGCTGTGGG CGGATGTCTT GGATAGATCA CGGGCTGGCT GAGCTGGACT 3360 TTGGTCAGCC TAGGTβAGAC TCACCTGTCC TTCTβGGGTC TTACTCCTCC TCAAGGAGTC 3420 TGTAGTGGAA AGGAG6CCAC AβAATAAGCT GCTTATTCTG AAACTTCACC TTCCTCTAGC 3480 CCGGCCCTCT CTAAGGβAGC CCTCTGCACT CGTGTGCAGG CTCTβACCAG GCAGAACAGG 3540 CAAGAGGGGA GGGAAGGAGA CCCCTGCAGG CTCCCTCCAC CCACCTTGAG ACCTGGGAGG 3600 ACTCAGTTTC TCCACAGCCT TCTCCAGCCT GTGTGATACA AGTTTGATCC CAGGAACTTG 3660 AβTTCTAAβC AβTβCTCβTG AAAAAAAAAA GCAGAAAGAA TTAGAAATAA ATAAAAACTA 3720 AβCACTTCTG GAGACAT
A169 Protein sequence Gene name : CEGP1 Unigene number: Hs.222399 Probeset Accession ft : AA256485 Protein Accession ft : CAB92285 Signal sequence : 1-31 Transmembrane domains : none
PFAM domains : EGF-like_domains [49-84 , 132-167 , 177-213 , 286 -321 , 407-442] CUB_domain [809-918]
Cellular Localization: may be secreted
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MGVAGRNRPβ AAWAVLLLLL LLPPLLLLAG AVPPGRGRAA GPQEDVDECA QGLDDCHADA 60 LCQNTPTSYK CSCKPGYQGE βRQCEDIDEC GNELNGGCVH DCLNIPGNYR CTCFDGFMLA 120 HDβHNCLDVD ECLENNGGCQ HTCVNVMGSY ECCCKEGFFL SDNQHTCIHR SEEGLSCMNK 180 DHβCSHICKE APRGSVACEC RPGFELAKNQ RDCILTCNHG NGGCQHSCDD TADGPECSCH 240 PQYKMHTDGR SCLEREDTVL EVTESNTTSV VDGDKRVKRR LLMETCAVNN GGCDRTCKDT 300 STGVHCSCPV GFTLQLDGKT CKDIDECQTR NGGCDHFCKN IVGSFDCGCK KGFKLLTDEK 360 SCQDVDECSL DRTCDHSCIN HPGTFACACN RGYTLYGFTH CβDTNECSIN NGGCQQVCVN 420 TVGSYECQCH PGYKLHWNKK DCVEVKGLLP TSVSPRVSLH CβKSββGDGC FLRCHSGIHL 480 SSDVTTIRTS VTFKLNEGKC SLKNAELFPE GLRPALPEKH SSVKESFRYV NLTCSSGKQV 540 PGAPGRPSTP KEMFITVEFE LETNQKEVTA SCDLSCIVKR TEKRLRKAIR TLRKAVHREQ 600 FHLQLSGMNL DVAKKPPRTS ERQAESCGVG QGHAENQCVS CRAGTYYDGA RERCILCPNG 660 TFQNEEGQMT CEPCPRPGNS GALKTPEAWN MSECGGLCQP GEYSADGFAP CQLCALGTFQ 720 PEAGRTSCFP CGGβLATKHQ βATSFQDCET RVQCSPGHFY NTTTHRCIRC PVGTYQPEFG 780 KNNCVSCPGN TTTDFDGSTN ITQCKNRRCβ GELGDFTGYI ESPNYPGNYP ANTECTWTIN 840 PPPKRRILIV VPEIFLPIED DCβDYLVMRK TSSSNSVTTY ETCQTYERPI AFTSRSKKLW 900 IQFKSNEGNS ARGFQVPYVT YDEDYQELIE DIVRDGRLYA SENHQEILKD KKLIKALFDV 960 LAHPQNYFKY TAQESREMFP RSFIRLLRSK VSRFLRPYK
A170 DNA sequence Gene name : DEME-6 protein (KIAA0452) Unigene number : Hs.125783 Probeset Acceεsion ft : AL039402 Nucleic Acid Accesεion AF007170 Coding sequence : 1-1725 (underlined sequences correspond to stop codon)
C 60 C 120
Figure imgf000913_0001
C 180
CTGGAGATGC AGGCCATGAT GACCTTTGAC CCTCAGGACA TCCTGCTTGC CGGCAACATG 240
ATβAAGGAGG CACAGATGCT GTGTCAGAGG CACCGGAGGA AGTCTTCTGT AACAGATTCC 300
TTCAGCAGCC TGGTGAACCG CCCCACGCTG GGCCAATTCA CTGAAGAAGA AATCCACGCT 360
GAGGTCTGCT ATGCAGAGTG CCTGCTGCAG CGAGCAGCCC TGACCTTCCT GCAGGACGAG 420
AACATGGTGA GCTTCATCAA AGGCββCATC AAAGTTCGAA ACAGCTACCA GACCTACAAG 480
GAGCTGGACA GCCTTGTTCA GTCCTCACAA TACTGCAAGG GTGAGAACCA CCCGCACTTT 540
GAAGGAGβAβ TGAAGCTTGG TGTAGGGGCC TTCAACCTGA CACTGTCCAT βCTTCCTACT 600
AGGATCCTGA GGCTGTTGβA GTTTGTGGGβ TTTTCAGGAA ACAAGGACTA TGGGCTGCTG 660
CAGCTGGAGG AGGGAGCGTC AGGGCACAGC TTCCGCTCTG TGCTCTGTGT CATGCTCCTG 720
CTGTGCTACC ACACCTTCCT CACCTTCGTG CTCGGTACTG GGAACGTCAA CATCGAGGAG 780
GCCGAGAAGC TCTTGAAGCC CTACCTGAAC CGGTACCCTA AGGGTβCCAT CTTCCTGTTC 840
TTTGCAGGGA GGATTGAAGT CATTAAAGGC AACATTGATG CAβCCATCCG GCGTTTCGAG 900
GAGTGCTGTG AGGCCCAGCA GCACTGGAAG CACTTTCACC ACATβTGCTA CTGGGAGCTG 960
ATGTGGTGCT TCACCTACAA GGβCCAβTGG AAGATGTCCT ACTTCTACGC CGACCTGCTC 1020
AGCAAGβAGA ACTGCTGGTC CAAββCCACC TACATTTACA TGAAGGCCGC CTACCTCAGC 1080
ATGTTTGGGA AGGAGGACCA CAAGCCGTTC GβGGACGACG AAGTGGAATT ATTTCGAGCT 1140
GTβCCAGGCC TGAAGCTCAA GATTGCTGGG AAATCTCTAC CCACAGAGAA GTTTGCCATC 1200
CGGAAGTCCC GGCGCTACTT CTCCTCCAAC CCTATCTCGC TGCCAGTGCC TGCTCTGGAA 1260
ATGATGTACA TCTGGAACGG CTACGCCGTG ATTGGβAAGC AGCCGAAACT CACGGATGGG 1320
ATACTTGAβA TTATCACTAA GGCTGAAGAG ATGCTββAGA AAGGCCCAGA GAACβAβTAC 1380
TCAGTGGATG ACGAGTGCTT GGTGAAATTG TTGAAAGβCC TGTGTCTGAA ATACCTGGβC 1440
CGTβTCCAGG AGGCCGAGGA GAATTTTAGG AGCATCTCTG CCAATGAAAA GAAGATTAAA 1500
TATGACCACT ACTTGATCCC AAACGCCCTβ CTGGAGCTGG CCCTGCTGCT TATGGAGCAA 1560
GACAGAAACG AAGAGGCCAT CAAACTTTTG GAATCTGCCA AGCAAAACTA CAAGAATTAC 1620
TCCATGGAGT CAAGGACACA CTTTCGAATC CAGGCAGCCA CACTCCAAGC CAAGTCTTCC 1680
CTAGA6AACA GCAGCAGATC CATGGTCTCA TCAGTGTCCT TGTAGCTTTG TGCAGCAGTT 1740
CCGGGCTGGA AGACAGAGAC AGCTGGACAG AGCTCCTGAA AACATTTCAA AATACCCCCT 1800
CCCCCTGCCC TGCCCTGCCT TTGGGGTCCA CCGGCACTCC AβTTGGATGG CACAACATAG 1860
TGTATCCGTG CAGAAGCCGA GCTGGCATTT TCACCAGTGT AGCCAAβGGC CTTTGCCAAG 1920
GGCAGAGCAG GTGGAGCCCT CTGCCTGCCC TATCACACAT ACGGGTACTT GCTTTTCACT 1980
GTGATGTTTA AGAGAATGTA TGAACAβTTT ACATTTTCCT TAGAAATACA TTGATGGβAT 2040
CACAGTTGGC TTTAAAAACC AACAACAATC AACCACCTGT AAGTCTTTGT CTTCACCTAT 2100
TATCATCTGG AGGTAAATCT CTTTATATGA TGATGCCAAA GβGCAAATTG CTTTTCAAAT 2160
TCAGCAAβTT CTCAGCTTGT GTGACGGAAG GTCCTTCAGA GβACCTGAGG AATGCCTGGβ 2220
AGAGGCTAAG CCTCAGGCTT CAATGCTTCT GGGGTTGββC ATGAGGATGT ACACAGACAC 2280
CCACTACCTT ACTACTCACA CTTCATTTCA CTCCTTTTGT AAATTTCCAA TTTAAAAATC 2340
AAGCACGTCT TTTTAGTβAβ ATAAAATCTG AGCTCTTCTG TAGAAAAATC AATCTCTACC 2400
AGTAGAAAAT GCCAGGGCTT GATGGAAGAG CTGTGTAGCC CTTTCTATGC CAAAGCCAGG 2460
AAATTTGGGG GGCAGGAGGA GGTTCTCAGA ATCCAGTCTG TATCTTTGCT GTATGCCAAA 2520
CTGAAACCAC TGββAATAAT TTATGAAACA TAAAAATCTT CTGTACTTCA CTCCAAGGTA 2580
CATTTGCTTA CTGACAGCAT TTTTGTTAAA ACTGTTATTC TTGAAAAAAA AAAAAAAAAA 2640 AA
A171 Protein sequence Gene name: DEME-6 protein (KIAA0452) Unigene number: Hs.125783 Probeset Accession ft: AL039402 Protein Accession ft: AAC39582 Signal sequence: none Transmembrane domains : 210-226 Cellular Localization: plasma membrane
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MTALDLFLTN QFSEALSYLK PRTKESMYHS LTYATILEMQ AMMTFDPQDI LLAGNMMKEA 60 QMLCQRHRRK SSVTDSFSSL VNRPTLGQFT EEEIHAEVCY AECLLQRAAL TFLQDENMVS 120 FIKGGIKVRN SYQTYKELDS LVQSSQYCKG ENHPHFEGβV KLGVGAFNLT LSMLPTRILR 180 LLEFVGFSGN KDYGLLQLEE GASGHSFRSV LCVMLLLCYH TFLTFVLGTG NVNIEEAEKL 240 LKPYLNRYPK GAIFLFFAGR IEVIKGNIDA AIRRFEECCE AQQHWKQFHH MCYWELMWCF 300 TYKGQWKMSY FYADLLSKEN CWSKATYIYM KAAYLSMFβK EDHKPFGDDE VELFRAVPGL 360 KLKIAGKSLP TEKFAIRKSR RYFSSNPISL PVPALEMMYI WNβYAVIGKQ PKLTDGILEI 420 ITKAEEMLEK GPENEYSVDD ECLVKLLKGL CLKYLGRVQE AEENFRSISA NEKKIKYDHY 480 LIPNALLELA LLLMEQDRNE EAIKLLESAK QNYKNYSMES RTHFRIQAAT LQAKSSLENS 540 SRSMVSSVSL
A172 DNA sequence Gene name: EST Unigene number: Hs.200102 Probeset Accession ft: AL117406 Nucleic Acid Accession ft: none found Coding sequence: 1-4044 (underlined sequences correspond to start and stop codons)
ATGACTAGGA 60
ATCGACATAG
Figure imgf000914_0001
120
GGCCCCTGGA GTCAGCAAGA GAGAAATCCT GAGGCTCCAG GβAGβGCAGC TGTCCCACCG 180
TGββGGAAGT ATβATβCTβC CTTGAGAACC ATGATTCCCT TCCβTCCCAA GCCGAGGTTT 240
CCTGCCCCCC AGCCCCTGGA CAATGCTGGC CTGTTCTCCT . ACCTCACCβT GTCATGGCTC 300
ACCCCβCTCA TGATCCAAAG CTTACGGAGT CGCTTAGATG AGAACACCAT CCCTCCACTG 360
TCAβTCCATG ATGCCTCAGA CAAAAATGTC CAAAGGCTTC ACCGCCTTTG GGAAGAAGAA 420
GTCTCAAGGC GAGGGATTGA AAAAGCTTCA GTβCTTCTGG TβATβCTGAG GTTCCAGAGA 480
ACAAGGTTGA TTTTCGATGC ACTTCTGGGC ATCTGCTTCT GCATTGCCAG TGTACTCGGG 540
CCAATATTGA TTATACCAAA GATCCTGGAA TATTCAGAAG AβCAGTTGGG GAATGTTGTC 600
CATGGAGTGG GACTCTGCTT TGCCCTTTTT CTCTCCGAAT GTGTβAAGTC TCTGAGTTTC 660
TCCTCCAGTT GGATCATCAA CCAACGCACA GCCATCAββT TCCGAGCAGC TGTTTCCTCC 720
TTTGCCTTTG AGAAGCTCAT CCAATTTAAG TCTGTAATAC ACATCACCTC AββAβAββCC 780
ATCAGCTTCT TCACCGGTGA TGTAAACTAC CTβTTTGAAG GGGTGTGCTA TββACCCCTA 840
GTACTGATCA CCTGCGCATC GCTGβTCATC TβCAβCATTT CTTCCTACTT CATTATTGGA 900
TACACTGCAT TTATTGCCAT CTTATGCTAT CTCCTGGTTT TCCCACTGGC GGTATTCATG 960
ACAAGAATGG CTGTGAAGGC TCAGCATCAC ACATCTGAGG TCAGCGACCA GCGCATCCGT 1020
GTGACCAGTG AAGTTCTCAC TTGCATTAAG CTβATTAAAA TGTACACATG GGAGAAACCA 1080
TTTGCAAAAA TCATTGAAGG TATGGAAAGT CTGACTTTCT GCTCCAAACC TGGTGATGGC 1140
ATGGCCTTCA GCATGCTGβC CTCCTTGAAT CTCCTTCββC TGTCAGTGTT CTTTGTGCCT 1200
ATTGCAGTCA AAGGTCTCAC GAATTCCAAG TCTGCAGTGA TGAGβTTCAA GAAGTTTTTC 1260
CTCCAGGAGA GCCCTGTTTT CTATGTCCAG ACATTACAAG ACCCCAGCAA AGCTCTGGTC 1320
TTTGAGGAGG CCACCTTGTC ATGβCAACAβ ACCTGTCCCG GGATCGTCAA TGGGGCACTG 1380
GAGCTGGAGA GGAACGGGCA TGCTTCTGAG βGGATGACCA GGCCTAGAGA TβCCCTCβGG 1440
CCAGAGGAAG AAGGGAACAG CCTGGGCCCA GAGTTGCACA AGATCAACCT GGTGGTGTCC 1500
AAGGGGATGA TGTTAGGGβT CTGCββCAAC ACGGGGAGTβ GTAAGAGCAG CCTGTTGTCA 1560
GCCATCCTGG AGGAGATGCA CTTGCTCGAG GGCTCGGTGG GGGTGCAGGG AAGCCTGGCC 1620
TATβTCCCCC AGCAGGCCTG GATCGTCAGC GGGAACATCA GGGAGAACAT CCTCATGGGA 1680
GGCGCATATG ACAAGβCCCG ATACCTCCAG GTGCTCCACT GCTGCTCCCT GAATCGGGAC 1740
CTGGAACTTC TGCCCTTTββ AGACATGACA GAGATTGGAG AGCGβGGCCT CAACCTCTCT 1800
GGGGGGCAGA AACAGAGGAT CAβCCTGGCC CGCGCCGTCT ATTCCGACCG TCAGATCTAC 1860
CTGCTGGACG ACCCCCTGTC TGCTGTβGAC GCCCACGTGG GGAAβCACAT TTTTGAβGAG 1920
TGCATTAAGA AGACACTCAG GGGGAAGACG GTCGTCCTGG TβACCCACCA GCTGCAGTAC 1980
TTAGAATTTT GTGGCCAGAT CATTTTGTTG GAAAATGGGA AAATCTGTGA AAATGGAACT 2040
CACAGTGAGT TAATGCAGAA AAAGGGGAAA TATGCCCAAC TTATCCAβAA βATβCACAAG 2100
GAAGCCACTT CGGACATGTT GCAGGACACA GCAAAGATAG CAβAGAAGCC AAAGβTAGAA 2160
AGTCAGGCTC TGGCCACCTC CCTGGAAGAG TCTCTCAACG GAAATGCTGT GCCGGAGCAT 2220
CAGCTCACAC AGβAGGAGGA GATGGAAGAA GGCTCCTTGA GTTGGAGGGT CTACCACCAC 2280
TACATCCAGG CAGCTGGAGG TTACATGGTC TCTTGCATAA TTTTCTTCTT CGTGGTGCTG 2340
ATCGTCTTCT TAACGATCTT CAGCTTCTGG TGβCTβAGCT ACTGGTTGGA GCAGGGCTCG 2400
GββACCAATA GCAGCCGAGA GAGCAATGGA ACCATGGCAβ ACCTGGGCAA CATTGCAβAC 2460
AATCCTCAAC TGTCCTTCTA CCAβCTββTβ TACββGCTCA ACGCCCTGCT CCTCATCTGT 2520 βTGGGGGTCT GCTCCTCAGG GATTTTCACC AAAGTCACGA GGAAGGCATC CACGGCCCTG 2580
CACAACAAβC TCTTCAACAA GGTTTTCCGC TGCCCCATβA GTTTCTTTGA CACCATCCCA 2640
ATAGGCCGGC TTTTGAACTG CTTCβCAGGG GACTTββAAC AβCTGGACCA GCTCTTGCCC 2700
ATCTTTTCAG AGCAGTTCCT GGTCCTGTCC TTAATGβTGA TCβCCGTCCT GTTGATTGTC 2760
AGTGTGCTGT CTCCATATAT CCTGTTAATβ GGAGCCATAA TCATβGTTAT TTGCTTCATT 2820
TATTATATGA TGTTCAAGAA GβCCATCβGT GTGTTCAAGA GACTGGAGAA CTATAGCCGG 2880
TCTCCTTTAT TCTCCCACAT CCTCAATTCT CTβCAAGGCC TGAGCTCCAT CCATGTCTAT 2940
GGAAAAACTG AAGACTTCAT CAGCCAGTTT AAβAββCTβA . CTGATGCGCA GAATAACTAC 3000
CTGCTGTTGT TTCTATCTTC CACACGATGG ATGGCATTGA . GβCTGGAGAT CATGACCAAC 3060
CTTGTβACCT TGβCTGTTGC CCTGTTCGTG βCTTTTGGCA . TTTCCTCCAC CCCCTACTCC 3120 TTTAAAGTCA TGGCTGTCAA CATCGTGCTG CAGCTGGCGT CCAGCTTCCA ββCCACTGCC 3180 CGGATTGβCT TGGAβACACA GGCACAGTTC ACGGCTGTAβ AGAGGATACT GCAGTACATβ 3240 AAGATGTGTG TCTCGGAAGC TCCTTTACAC ATGGAAGGCA CAAGTTGTCC CCAGGββTGG 3300 CCACAGCATG GββAAATCAT ATTTCAGGAT TATCACATGA AATACAGAGA CAACACACCC 3360 ACCGTGCTTC ACCGCATCAA CCTGACCATC CGCGGCCACG AAβTGGTGGG CATCGTGββA 3420 AGGACGββCT CTGββAAGTC CTCCTTGGGC ATGGCTCTCT TCCGCCTGGT GGAGCCCATG 3480 GCAGβCCCGA TTCTCATTGA CGGCGTGβAC ATTTGCAGCA TCGGCCTGGA GGACTTGCGG 3540 TCCAAGCTCT CAGTGATCCC TCAACATCCA GTGCTGCTCT CAGGAACCAT CAGATTCAAC 3600 CTAGATCCCT TTGACCGTCA CACTGACCAG CAGATCTGββ ATGCCTTGGA GAGGACATTC 3660 CTGACCAAGβ CCATCTCAAA GTTCCCCAAA AAGCTGCATA CAGATGTGGT GGAAAACGGT 3720 GGAAACTTCT CTGTGGGGGA GAGGCAGCTG CTCTGCATTG CCAGGGCTβT GCTTCβCAAC 3780 TCCAAGATCA TCCTTATCGA TGAAGCCACA GCCTCCATTG ACATGGA6AC AβACACCCTG 3840 ATCCAGCGCA CAATCCGTGA AGCCTTCCAG GGCTGCACCG TGCTCGTCAT TGCCCACC6T 3900 βTCACCACTβ TGCTGAACTG TGACCACATC CTGGTTATGG GCAATGGGAA GGTββTAβAA 3960 TTTGATCGβC CGGAGGTACT GCGGAAGAAG CCTGGGTCAT TGTTCGCAGC CCTCATββCC 4020 ACAGCCACTT CTTCACTGAG ATAAGGAGAT GTGGAGACTT CATGGAGβCT ββCAGCTGAG 4080 CTCAGAGGTT CACACAGGTG CAGCTTCGAG GCCCACAGTC TGCGACCTTC TTGTTTβGAG 4140 ATGAGAACTT CTCCTGGAAG CAGGGGTAAA TGTAGGGβGG GTGGβGATTG CTGβATβGAA 4200 ACCCTGGAAT AGGCTACTTG ATGGCTCTCA AGACCTTAβA ACCCCAGAAC CATCTAAGAC 4260 ATGGGATTCA GTGATCATGT GGTTCTCCTT TTAACTTACA TGCTGAATAA TTTTATAATA 4320 AGGTAAAAGC TTATAGTTTT CTGATCTGTG TTAGAAGTGY TGCAAATGCT βTACTGACTT 4380 TGTAAAATAT AAAACTAAGG AAAACTCAAA AAAAAAAAAA AAAAAAA
A173 Protein sequence Gene name: EST Unigene number: Hs.200102 Probeset Accesεion ft: AL117406 Protein Accession ft: none found Signal sequence: none found Transmembrane domainε : 169-185, 199-215, 275-291, 304-320, 387-403, 770-786, 829-845, 907-923, 927- 943,1018-1034 PFAM domains: ABC.transporter [502-673] , ABC_membrane_region [163-432, 771-1060] ATP-binding_domains [508-516, 1139-1147]
Cellular Localization: plasma membrane
31 41 51
MTRKRTYWVP NSSGGLVNRG IDIGDDMVSG LIYKTYTLQD GPWSQQE NP EAPGRAAVPP 60
WGKYDAALRT MIPFRPKPRF PAPQPLDNAG LFSYLTVSWL TPLMIQSLRS RLDENTIPPL 120
SVHDASDKNV QRLHRLWEEE VSRRGIEKAS VLLVMLRFQR TRLIFDALLG ICFCIASVLG 180
PILIIPKILE YSEEQLGNW HGVGLCFALF LSECVKSLSF SSSWIINQRT AIRFRAAVSS 240
FAFEKLIQFK SVIHITSGEA ISFFTGDVNY LFEGVCYGPL VLITCASLVI CSISSYFIIG 300
YTAFIAILCY LLVFPLAVFM TRMAVKAQHH TSEVSDQRIR VTSEVLTCIK LIKMYTWEKP 360
FAKIIEGMES LTFCSKPGDG MAFSMLASLN LLRLSVFFVP IAVKGLTNSK SAVMRFKKFF 420
LQESPVFYVQ TLQDPSKALV FEEATLSWQQ TCPGIVNGAL ELERNGHASE GMTRPRDALG 480
PEEEβNSLGP ELHKINLWS KGMMLβVCGN TβSGKSSLLS AILEEMHLLE GSVGVQGSLA 540
YVPQQAWIVS GNIRENILMG GAYDKARYLQ VLHCCSLNRD LELLPFGDMT EIGERGLNLS 600
GGQKQRISLA RAVYSDRQIY LLDDPLSAVD AHVGKHIFEE CIKKTLRGKT WLVTHQLQY 660
LEFCGQIILL ENGKICENGT HSELMQKKGK YAQLIQKMHK EATSDMLQDT AKIAEKPKVE 720
SQALATSLEE SLNGNAVPEH QLTQEEEMEE GSLSWRVYHH YIQAAGGYMV SCIIFFFWL 780
IVFLTIFSFW WLSYWLEQGS GTNSSRESNG TMADLGNIAD NPQLSFYQLV YGLNALLLIC 840
VGVCSSGIFT KVTRKASTAL HNKLFNKVFR CPMSFFDTIP IGRLLNCFAG DLEQLDQLLP 900
IFSEQFLVLS LMVIAVLLIV SVLSPYILLM GAIIMVICFI YYMMFKKAIG VFKRLENYSR 960
SPLFSHILNS LQGLSSIHVY GKTEDFISQF KRLTDAQNNY LLLFLSSTRW MALRLEIMTN 1020
LVTLAVALFV AFGISSTPYS FKVMAVNIVL QLASSFQATA RIGLETEAQF TAVERILQYM 1080
KMCVSEAPLH MEGTSCPQGW PQHGEIIFQD YHMKYRDNTP TVLHβlNLTI RGHEWβlVG 1140
RTGSβKSSLG MALFRLVEPM AGRILIDGVD ICSIβLEDLR SKLSVIPQDP VLLSGTIRFN 1200
LDPFDRHTDQ QIWDALERTF LTKAISKFPK KLHTDWENG GNFSVGERQL LCIARAVLRN 1260
SKIILIDEAT ASIDMETDTL IQRTIREAFQ GCTVLVIAHR VTTVLNCDHI LVMβNGKWE 1320
FDRPEVLRKK PGSLFAALMA TATSSLR
A174 DNA sequence Gene name: ESTs Unigene number: Hs.128899 Probeset Accession # : AA983251 Nucleic Acid Accesεion ft: AA983251 Coding sequence: 1-1749 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I
ATGCTβTCTG GCTTCTTGAT GAGTCCCAGT ACCCAGCACA GAGCACAGTA CACTCCCGGA 60 GGAAAGAAAC TTCCGTGGGA GGCTTCCATC GGTGCGCACA CCTCCCGAGG GCGAGGCAGC 120 GACCGβGAβA GGGAGAGCCG GCCβGAβGCT GCCGGGCTCC TGTGGGACCG CGCTGCAGCC 180 GGGGAGβCββ AGAA6GGGAA CCGGββCβAG CCGCCCGCCT GGATCCGCGC CCAGCAGCAG 240 CCGCGGCCGC CGCCAGCTGG GCAGGCTCCC GGGACTGCGG CTGGGGGCGC GCAGGACCCT 300 CGCCTGCGTC CTGGACGTTC CCGβGGβAGG GTCCGGTTGC CAGTGAAACC TCCAGAGGCT 360 TCCGGACGAC AGCCCCGGGG GCCTTCTGAC TGCATCCCGA GATTTCCATC AGCGAGTGCA 420 ACTCATAAGG CAGTCCCTAA GGGGACCGGβ CCACCGGCTG AGGACGGββA TGβCTTAGGA 480 GCTCCTGGAC CTAGGGCCCG GCGTCGTCGC CTCCTGGGCG TCGCββCAβA GβGGAGTβGC 540 CCGCGCGGAA AGCGCCGCGG GACAGTCAGT GACGAGGCCC GGGGGTCGCC GGGβCCACGA 600 CTTCTCGGAG ACCGTCCTGC GCTCTCTGGA GACGCGCTβT CCGCGCCCAG GGTGGTβCCA 660 TGTGGGGCGC TCGCCGCTCG TCCGTCTCCT CATCCTGGAA CGCCβCTTCG CTCCTGCAGC 720 TGCTGCTGGC TGCGCTGCTG GCGGCGGβββ CGAGGGCCCA GCGGCGAGTA CTGCCACGGC 780 TGGCTGGACG CGCAGGGCGT CTGGCGCATC GGCTTCCAGT GTCCCGAGCG CTTCGACGGC 840
GGCGACGCCA CCATCTGCTG CGGCAGCTGC GCGTTGCGCT ACTGCTGCTC CAGCGCCGAG 900
GCGCGCCTGβ ACCAGGβCGG CTGCGACAAT GACCGCCAGC AGGGCGCTGβ CGAGCCTGGC 960
CGGGCGGACA AAGACGββCC CCGACGGCTC GGCAGGGCTT CATGTCTTAG CGGTACCCAA 1020 βGAGACGGCG AGGGTGCGCC CCCACCCGTG AGGGCCTGGC AGCGGTGCTC CCCTGAAGGC 1080
TCCCCGAAAG GAAGGCAGCT CCTCAGGGCT TTCCCGGGGC TGCTGCCCCG TGCCAGACGC 1140
CGCββATTCC CATCTTCTCC ACβCGGCGβC CCCTCTCCCC TGCAGCGGCC CGCCTTGCCC 1200
ATCTACGTGC CGTTCCTCAT TGTTGGCTCC GTGTTTβTCG CCTTTATCAT CTTGβGGTCC 1260
CTGGTGGCAG CCTGTTGCTG CAGATGTCTC CGGCCTAAGC AGGATCCCCA GCAGAGCCGA 1320
GCCCCAGGGβ GTAACCGCTT GATGGAGACC ATCCCCATGA TCCCCAGTGC CAGCACCTCC 1380
CGGGGGTCGT CCTCACGCCA GTCCAGCACA GCTGCCAGTT CCAGCTCCAG CGCCAACTCC 1440
GGGGCCCGGG CGCCCCCAAC AAGGTCACAG ACCAACTGTT GCTTGCCGGA AGGGACCATG 1500
AACAACGTGT ATGTCAACAT GCCCACGAAT TTCTCTGTGC TGAACTβTCA GCAGGCCACC 1560
CAGATTGTβC CACATCAAGG GCAGTATCTG CATCCCCCAT ACGTGβGGTA CACGGTβCAG 1620
CACGACTCTG TGCCCATGAC AGCTGTGCCA CCTTTCATGG ACGGCCTGCA GCCTG CTAC 1680
AGGCAGATTC AGTCCCCCTT CCCTCACACC AACAGTGAAC AGAAβATGTA CCCAGCββTβ 1740
ACTGTATAAC CGAGAGTCAC TGGTGGGTTC CTTTACTGAA GGGAGACGAA GGCAGGGβTβ 1800
GATTCTCβAβ GTGGAAGTCC GCACATGTCG GTGGTATTTA TGGCACGATT CCTTTGGATG 1860
GCTTCATTTC CCCCCAGACT GTATGAAAAC ATCTCCGAAT TAGCATTTCT GGATATGTTT 1920
CATCCAβββT ATCATTGATT TATGATGGAA AACCGGCCTC AGCTGGAGAT GACTGTβATG 1980
TTGCTGATββ GTGTATAACA AATGCTTGAG TCCGAAGTGC CCTTGAGATA TGβTTGACβA 2040
AAGAATTTTA TAAACTGATA AATTAAGGAT TTTTATTATG TTGTTATTAT TATTTCTTTT 2100
TTGTTGTTGA CTGCACAGGA TCAAAATGCC T6TTATCTCC CTTTTACTGG βACTTTTTTT 2160 ττττττττττ TTTTTTTTAA TCAβACAGGG TCTTGCTCTG TTβCCCAGGC TGGAβTβCAG 2220
TGGTGCGATC TCGGCTCACT GCAACTTCAβ CCTCCTGGAT TCAGGCAACA CTCCTGCCTC 2280
AGCCTCCCAC GTGGCTGGGA TTACAGGTGC CTGCCCCCAT GGCTAATTTT TTGTATTTTT 2340
TGTAGAGATG GGGTTTCACC ATGTTGGCTG GGCTGGTCTC ACTCTCCTGA CCTCAAGCAA 2400
TCTGCCTGTC TCAGCCTCCC AAAGTGCTGG GATTACAGGC GTGAGCCACC GCCCCCAGCC 2460
TGAGCCTTTT TTTTTTTCTA ATGCATCCAA GGTTAAGGGG AAGACGCAAA TAACAGGACT 2520
ATTCTAAAAβ βAAACCTGTT TGAACTCTGT GAGATCAGTC ATCAGTCTCA GTATTCCACA 2580
GβCACACCTT AATTTCATTG TAAAAAGATA TATATATTTT GTCTATTTTT GTGCTTTTGG 2640
GβGCCTATTT TGTβCTTTTT TACCTTATGT AGAGATCTTA TTACAAAGTG ATTTTCTACA 2700
TTAAAAAGAG ACTβAAATAA ATTβTATAGT TACTTAACTA ATGAAGACAT TTCAGAACTC 2760
TGβGATGATT TTAATCTTGA AGTAGTAGGT GGTATAGTCA TAAAACCATT CATCCCCTTC 2820
TTGATTGTAT CTTAATTTTC TCGCTTTAAβ GTGACATCTG AGAGGTAATβ CATTCTTTTT 2880
TATATTGAAA TCATAAACTA TCACCCGCTG CTTCTCTGAG TTACTTTTAA TTTTGCCTTG 2940
TGGTTATGGT TTGβCβTTTC CTTCTGTTTG GTTTTCAGAG CCCCATGTCT ATATAGTCCT 3000
GAGTGCAAGT AATTACTATA CTTGTAAATβ AAGATCAGTA TTTCTGCCTA GATCTβATAA 3060
AAAAATTTTC TTGTCTTAGT TATAAAAATT CAAAGAAATG TGTTACAAAG ATACTTAGTA 3120
TAGCTCCTCA GCCATAACCT GAβACTTGGG ATGAAATTTA AACCAGATAC GATTTACTTT 3180
GCAGATCATA AGGCTTTTTA TACTCTTGTT ATCAAAATββ CTTATTTTTC AGGCACTAAG 3240
GATTGTTAAG AGAAAAGCTT TTCAACGAAG βATTGCCTTT CTTCTCCCAC ACTGTTCTTG 3300
ATTTCCTCTC TCTTTCAGβC CTCAACAGGC ACTGTATTCA TTGCCAATGT TCCAAATTAT 3360
CAAATTCAAβ TGAATTTATT TGTβTGTTCT TTACTTATAT AAAAAAAGAT AACTTTAAGG 3420
ATGTβCAAβT ACATTTCCAA CTGCTAGCAC AACCAGTATT TTβTAATTAA ACAAATCGCT 3480
GTATGGTATG GTCTTCTACA CATTTATGTC TATAβATATC TATCGATCAT CTTTCTATTC 3540
TGTTTCATGA CTGAATAATG TAAAACCAGT GTTβGCAATT GGTATCATCA ATGATACTCA 3600
TTTTTTAATA ACCAAAGGCA GGGGAAAATC ATTTTACTTA TTAATAAATA TTTTATGATG 3660 TGAAAAAAAA AAAAAAAAAA AAAAAAAAAA
A175 Protem sequence
Gene name : ESTs
Unigene number : Hs . 128899
Protem Accession # : none found
Signal sequence : 1-11
Transmembrane domains : 402 -424
Cellular Localization: not determined
1 11 21 31 41 51
M ILSGFLMSPS TIQHRAQYTPG GIKKLPWEASI GIAHTSRGRGS DIRERESRPEA AIGLLWDRAAA 60
GEAEKGNRGE PPAWIRAQQQ PRPPPAGQAP GTAAGGAQDP RLRPGRSRGR VRLPVKPPEA 120
SGRQPRGPSD CIPRFPSASA THKAVPKGTG PPAEDGDGLG APGPRARRRR LLGVAAEGSG 180
PRβKRRGTVS DEARGSPβPR LLGDRPALSG DALSAPRWP CGALAARPSP HPGTPLRSCS 240
CCWLRCWRRβ RGPSGEYCHG WLDAQGVWRI GFQCPERFDG GDATICCGSC ALRYCCSSAE 300
ARLDQGGCDN DRQQGAGEPG RADKDGPRRL GRASCLRGTQ GDGEGAPPPV RAWQRCSPEG 360
SPKβRQLLRA FPβLLPRARR RGFPSSPRGG PSPLQRPALP IYVPFLIVGS VFVAFIILGS 420
LVAACCCRCL RPKQDPQQSR APGGNRLMET IPMIPSASTS RGSSSRQSST AASSSSSANS 480
GARAPPTRSQ TNCCLPEGTM NNVYVNMPTN FSVLNCQQAT QIVPHQGQYL HPPYVGYTVQ 540 HDSVPMTAVP PFMDGLQPGY RQIQSPFPHT NSEQKMYPAV TV
A176 DNA SEQUENCE
Gene name- ESTs, Weakly similar to CGHU7L collagen alpha 1 (III) chain precursor [H.sapiens]
Unigene number: Hs.19322
Probeset Accession #: AA088458
Nucleic Acid Accession ft- AA088458
Coding seguence: 862-1995 (underlined sequences correspond to start and stop codons)
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I I I 1 I I
GCCCTTGGAC ACTGACATCG ACTGAAβGAG TAGAATGGAG CACGAGGACA CTGACATββA 60 CTGAAGAAAA AGGAGCTGGA GCAGGAGAAβ βAGGTGCTGC TGCAGGGTTT GGAGATGATG 120
GCGCGGGGCC βCCACTGGTA CCAGCAGCAG CTCCAACGAG TGCAGGAGCG CCAGCβCCβC 180
CTGGGCCAGA GCAGAβCCAG CGCCβACTTT GGβGCTGCAG ββAGCCCCCG CCCACTββGG 240
CGGCTACTGC CCAAGGTACA AβAGGTGGCC CGGTGCCTGG GGGAGCTGCT GGCTGCA6CC 300
TGTGCCAGCC GGGCCCTGCC CCCGTCCTCC TCCGGGCCCC CCTGCCCTGC CCTGACβTCC 360
ACCTCACCCC CGGTCTGGCA CCAGCAGACC ATCCTCATGC TGAAββAβCA GAACCGACTC 420
CTCACCCAGG AGGTGACCGA GAAGAGTGAG CβCATCACCC ACCTGGAGCA GGAGAAGTCβ 480
GCGCTCATTA AGCAGCTGTT TGAβGCCCGC βCCCTGAGCC AGCACβACGG GGGACCTCTβ 540
GATTCCACCT TCATCTAGTC CTTGTGGGCC GCGTGGGCCC CCAGGβCCAβ CCTCβCACTC 600
AGCCCTTCGA GGGTGGGCGC CCCATCGCAC CCACCCTCTC TGGCTGGAGA CCCCCGβCAG 660
GCCCAGGCAC AGTCCCGGAG TGGGCGCCTT CCTGCCβCCC TTGCCAGATG GGCTCCCCAG 720
GCCTGCCCCC GGCTGGTCCC CGCACCGAβC βCTTCACTCC βTTTKβGCTC CTGGTTGYTG 780
ACATGGGCTG GGGGCTCTCT TGAGTCCGCA TAβTCCGCAG CTACTACTGG CCGCTGTCAG 840
TGGACAGTGG GGTACCCCTC CATGAGTTAG CGTCCCCCCG TTTCCAβCGG TGCCGCCCTG 900
GGTCCCATCT TCAGβGAAAβ GCACTGCCCA CGCCAGGCTG CACTTCCAAC AACGGGCAGC 960
AGAGGβCGCG GGGCGGCTCC GACGCGGGTC CAAGGGCAGC TTCCCGCTCA ACCAGGβCAC 1020
CAGGACβAGG TGGCTGTAβC TCGGACGGAC GβAAGTAGAT GGAβGGGGTG GGGACGβCCT 1080
GTAAGCGGGG GGTβCCTGCC TGGCTGGGGA GCCCCAGGGA TAGCGGTCGG ACTTCAGGTT 1140
CTGGCCAAGG CTGAβGGACC CTGGCTGCAG CGGATCGGCA CGCCGGGTββ βCβAβAGCTT 1200
GGCCTGCATG TGCCTCCCAC AGACCCTGGG βTGATGβCCT TCCCCCTCTT GGCCGGβACG 1260
TTβCCCCACG TTGAGTCCCA CACAACATCC TGTGAGCCTG GCTCCCCAββ AβGGCCCCCA 1320
GACAGCTCCC AGGCACGTCA TAGGCAAAGC CTGTTTCCCC CβACTCAGGA TTTCCAAGGC 13 BO
CTGGGGTCCT GCTCACCCCC CTTTGCTCTC ACGCCCAGCC TGTCCCCAGG TTTCAGCTGG 1440
GAGAGGCCAC CTCCCTCAGC CAAGGAAAAC GAGAACCCCC AGGGTACAGG AGGAGGCTGG 1500
GGCAGGTCCC CTTGGGTGTC ACTCCCTCAG CCCCTGCCCA GGCCCACTCC CGCTGGTGCT 1560
GGAGTACGCA CTCβTGGGGG GβCCCTGCTC AβCCCAACCT GGAGGGTCCC AGTGTCACCA 1620
GAACCAGGGG CACGGCAACA GCATCGATGG GTTCTβCAGC CCAGGGCCCC CGATGCGGGG 1680
TCAGTβTGTG TGGGGCGCAG GGCCTCCGAT GCGGGGTCAβ TβCGTGGβββ GCβCAβββCC 1740
CCCGATGCGG βGTCAGTGCG TGGGGGGCGC AGGβCCCCCT CGTGTCCAGG GCACTTTGGT 1800
ACACTGTCCC ACAAGGCACC TGTCTCAGAG GAβGGβCCCT GGCAGGCAβC GTGGCAACTC 1860
CCTTCCGGAG CCCAGCTCCA TGCTAACCTG CCCACAGCAA CCCCACAGAG CCACATTCCC 1920
TGCTGCACCT GGTCTβCAβG GGTGTCCCAG GACAGGCCCA AGTCAβCCCA βCATGCAGCT 1980
GCCCTCCTAC CCTGAAGATG ββAGTGGGCT TTCCAGβGGA CATAAGGATG TCAGβCCTGG 2040
ACCTCCTGGG CAGGAAAGGG TGCAGGTCCT GAGGGCCTGT GCCCCACAβC CCCAβCACCC 2100
AGGTGGACTG CAGCGCAGTG GGTGGGCCAG TGGCAβCCAβ GGAβAAβCCC CCCβTCAβCA 2160
GGCTGβGGTC TGCCCACCAG ββCCTCCCCA CGTCTGCCTT TGAGGGTGCC TβCCATβCCC 2220
TGGGβGATCC TGGCATCTTT ACTGGACTGG AAGCAGGAGA CAGAACAβTG TCTGTCCCGG 2280
GGTGACTTCA TCAGGAGACC GCCCACATAG AGCTGGACCC CGCAβCTβAA βCββAAATβT 2340
GAGACAGGCT GβCACCTCCG GAAAAACTGC CTTTCAGCCT TGGTGTTCCG TGCAAGGTGA 2400
AAAGAAATAG βTCCTCCCAG TTTACAGCTT GAAATCAGGC TAGTGAGTGG CCCTGGAGAC 2460
CACGAGGGGA GAATTTAAAG GCCCCGGCTG GCAGGGTCTA GGTGGCTGGC AGAGGCACAT 2520
GCAGACCCTG CCTGGAGCCT GCCCTAGGAC GCTGGGCGGG TCAGTCTCCG TGCAGGATGT 2580
GAβCAGCGTC CCTGGGCTCT ATCCGCGAβG TGCCAGTAGC GTGTGCAGGT ACATACACGT 2640
GCGTGCACAC TGTGATGACA CCCGβAAATβ TCTCAGGATG TTGAAATGTG TCCTTGGGGG 2700
CAGAAGTGTC CCCAGTTGAG AATCTGCCCC AGAGGAACAC ACCCACACCA GGCCTCAGGA 2760
TTTTGTGTTG ATCAAGTTCC AAGGAAAAGG AACATCTCAG CCGGGCGTGG TGGTTCACGC 2820
CTGβAATCCC AGCACTTGAG GCCAGGAβTT CCAGAGCAGC CTGGGCAACG CAGTGAGAGA 2880
CCCCATCTCT ACAARAAAAA AAAAAGAAAG AAAβAAAATG AGAGATCCAβ GTTTAAAAAT 2940
TCATAAACAC CACAAGGAAA CAATACACTA TGAβACCCAβ CAβAAGCAAC AGATTGACTC 3000
TAGACCCAGA TACTAGAATT ATCAGAGAGA ATATAAAGTA ACAGTGTTTT ATATATCTAA 3060 AGAAATAAAA GAGATTTCTG GAAACATGAA AAAAAA
A177 DNA SEQUENCE Gene name: Cadherin 3, P-cadherin (placental) Unigene number: Hs.2877 Probeset Accession #: X63629 Nucleic Acid Accession #: X63629 Coding sequence: 54-2543 (start and stop codons are underlined)
11 21 31 41 51
I I I I
GCGGAACACC GGCCCGCCGT CGCGGCAGCT GCTTCACCCC TCTCTCTGCA GCCATGGGGC 60 TCCCTCGTGG ACCTCTCGCG TCTCTCCTCC TTCTCCAGGT TTGCTGGCTG CAGTGCGCGG 120 CCTCCGAβCC GTGCCGGGCG GTCTTCAβββ AGGCTGAAβT GACCTTGGAG GCGGGAGGCG 180 CGGAGCAGGA GCCCGGCCAG GCCCTGGGβA AAβTATTCAT GGGCTGCCCT GGGCAAGAGC 240 CAGCTCTGTT TAGCACTGAT AATGATGACT TCACTGTGCG GAATGβCβAβ ACAGTCCAGG 300 AAAGAAGGTC ACTGAAGGAA AββAATCCAT TGAAGATCTT CCCATCCAAA CGTATCTTAC 360 GAAGACACAA GAβAGATTGG GTGGTTGCTC CAATATCTβT CCCTGAAAAT GGCAAGGGTC 420 CCTTCCCCCA GAGACTGAAT CAβCTCAAβT CTAATAAAβA TAGAGACACC AAGATTTTCT 480 ACAGCATCAC GββGCCGGGG βCAGACAGCC CCCCTGAGGG TGTCTTCGCT GTAGAGAAGG 540 AGACAGGCTG GTTGTTGTTG AATAAGCCAC TGGACCGGGA GGAGATTGCC AAGTATGAGC 600 TCTTTGGCCA CGCTGTGTCA GAGAATGGTβ CCTCAGTGGA GGACCCCATG AACATCTCCA 660 TCATCGTGAC CGACCAGAAT GACCACAAGC CCAAGTTTAC CCAGGACACC TTCCGAGGGA 720 GTGTCTTAGA GGGAGTCCTA CCAGGTACTT CTGTβATGCA ββTβACAβCC ACAGATβAββ 780 ATGATGCCAT CTACACCTAC AATGGGGTGβ TTGCTTACTC CATCCATAβC CAAβAACCAA 840 AGGACCCACA CGACCTCATG TTCACAATTC ACCββAGCAC AββCACCATC AβCGTCATCT 900 CCAGTGGCCT GβACCGGGAA AAAGTCCCTG AβTACACACT GACCATCCAG GCCACAGACA 960 TGβATGGGGA CGGCTCCACC ACCACGGCAG TGGCAβTAGT GGAGATCCTT GATGCCAATG 1020 ACAATβCTCC CATGTTTGAC CCCCAGAAGT ACGAGGCCCA TGTGCCTGAG AATGCAGTβG 1080 GCCATβAGGT GCAGAGGCTG ACGGTCACTβ ATCTGGACβC CCCCAACTCA CCAGCβTGGC 1140 GTGCCACCTA CCTTATCATG GGCCGTβACβ ACGGGGACCA TTTTACCATC ACCACCCACC 1200 CTGAGAGCAA CCAGGGCATC CTGACAACCA GGAAGGGTTT GGATTTTGAG GCCAAAAACC 1260 AGCACACCCT GTACβTTβAA GTGACCAACG AGGCCCCTTT TGTGCTGAAG CTCCCAACCT 1320 CCACAGCCAC CATAGTGGTC CACGTGGAGG ATGTGAATGA GGCACCTGTG TTTGTCCCAC 1380 CCTCCAAAGT CGTTGAGGTC CAGGAGGGCA TCCCCACTGG GβAGCCTGTG TGTβTCTACA 1440
CTβCACAAGA CCCTGACAAG GAGAATCAAA AGATCAGCTA CCGCATCCTG AGAβACCCAG 1500
CAGGGTββCT AGCCATGGAC CCAGACAGTG GGCAGGTCAC AGCTGTGββC ACCCTCGACC 1560
GTGAGGATGA GCAGTTTGTG AGGAACAACA TCTATGAAGT CATGGTCTTβ βCCATGGACA 1620
ATGGAAGCCC TCCCACCACT GGCACGGGAA CCCTTCTGCT AACACTGATT GATβTCAACG 1680
ACCATGGCCC AGTCCCTGAβ CCCCGTCAGA TCACCATCTG CAACCAAAGC CCTGTGCGCC 1740
ACGTGCTGAA CATCACGGAC AAGGACCTGT CTCCCCACAC CTCCCCTTTC CAGGCCCAβC 1800
TCACAβATGA CTCAGACATC TACTGGACGG CAGAGGTCAA CGAGβAAGGT βACACAβTGG 1860
TCTTGTCCCT GAAGAAGTTC CTGAAGCAGG ATACATATGA CGTGCACCTT TCTCTGTCTG 1920
ACCATGGCAA CAAAGAGCAG CTGACGβTGA TCAGGGCCAC TGTGTGCGAC TGCCATGGCC 1980
ATGTCGAAAC CTCCCCTGGA CCCTGGAAAG GAββTTTCAT CCTCCCTGTG CTGβββGCTG 2040
TCCTGGCTCT GCTGTTCCTC CTGCTGGTGC TGCTTTTGTT GGTGAGAAAG AAGCβGAAGA 2100
TCAAGGAGCC CCTCCTACTC CCAGAAGATG ACACCCGTGA CAACβTCTTC TACTATGGCG 2160
AAGAGβGGGG TGβCβAAGAG GACCAGGACT ATGACATCAC CCAGCTCCAC CGAGGTCTGG 2220
AGGCCAGGCC GGAGGTGGTT CTCCGCAATG ACGTββCACC AACCATCATC CCGACACCCA 2280
TGTACCGTCC TAGGCCAGCC AACCCAGATG AAATCGGCAA CTTTATAATT GAGAACCTGA 2340
AGGCGGCTAA CACAGACCCC ACAGCCCCGC CCTACGACAC CCTCTTGGTG TTCGACTATG 2400
AGGGCAGCGG CTCCGACGCC GCGTCCCTGA GCTCCCTCAC CTCCTCCGCC TCCGACCAAG 2460
ACCAAGATTA CGATTATCTG AACGAβTβββ GCAGCCGCTT CAAGAAGCTG GCAGACATGT 2520
ACGβTββCGG ββAβGACGAC TAGGCGGCCT GCCTβCAβGG CTGGGGACCA AACGTCAGGC 2580
CACAGAGCAT CTCCAAGGGG TCTCAGTTCC CCCTTCAGCT GAGGACTTCG GAβCTTβTCA 2640
GGAAGTβGCC GTAGCAACTT GGCGGAβACA βGCTATGAGT CTGACGTTAG AGTGGTTGCT 2700
TCCTTAGCCT TTCAGGATGG AGGAATGTGG GCAβTTTGAC TTCAGCACTG AAAACCTCTC 2760
CACCTGGGCC AGGGTTGCCT CAGAββCCAA GTTTCCAGAA GCCTCTTACC TGCCGTAAAA 2820
TGCTCAACCC TGTβTCCTGG GCCTGβGCCT GCTGTGACTG ACCTACAGTG GACTTTCTCT 2880
CTGGAATGGA ACCTTCTTAG GCCTCCTGGT GCAACTTAAT TTTTTTTTTT AATβCTATCT 2940
TCAAAACGTT AGAβAAAβTT CTTCAAAAβT βCAβCCCAβA GCTGCTGGGC CCACTGβCCG 3000
TCCTβCATTT CTββTTTCCA GACCCCAATG CCTCCCATTC GGATGGATCT CTGCGTTTTT 3060
ATACTGAGTG TGCCTAGGTT GCCCCTTATT TTTTATTTTC CCTGTTβCβT TCCTATAGAT 3120 GAAβββTβAβ βACAATCGTG TATATGTACT AGAACTTTTT TATTAAAGAA A
A178 Protein sequence : βene name: Cadherin 3, P-cadherin (placental)
Unigene number: Hs.2877
Probeset Accession #: X63629
Protein Accession ft: CAA45177
Signal sequence: 1-24
Transmembrane domain: 659-675
Cellular localization: plaεma membrane
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I I I I I I
MβLPRβPLAS LLLLQVCWLQ CAASEPCRAV FREAEVTLEA ββAEQEPGQA LGKVFMGCPβ 60
QEPALFSTDN DDFTVRNβET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENβ 120
KGPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK 180
YELFGHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RGSVLEGVLP GTSVMQVTAT 240
DEDDAIYTYN GWAYSIHSQ EPKDPHDLMF TIHRSTGTIS VISSGLDREK VPEYTLTIQA 300
TDMDGDGSTT TAVAWEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP 360
AWRATYLIMG GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL 420
PTSTATIWH VEDVNEAPVF VPPSKWEVQ EGIPTGEPVC VYTAEDPDKE NQKIΞYRILR 480
DPAGWLAMDP DSβQVTAVβT LDREDEQFVR NNIYEVMVLA MDNβSPPTTG TGTLLLTLID 540
VNDHGPVPEP RQITICNQSP VRHVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD 600
TWLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL 660
GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YGEEGGGEED QDYDITQLHR 720
GLEARPEWL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF 780 DYEGSGSDAA SLSSLTSSAS DQDQDYDYLN EWGSRFKKLA DMYGGβEDD
A179 DNA SEQUENCE
Gene name: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7
Unigene number: Hs.258583
Probeset Accession ft: NM_012152
Nucleic Acid Accession #: NM_012152
Coding sequence: 43-1104 (underlined sequences correspond to start and stop codons)
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I I I I I I
CTTCTTTAAA TTTCTTTCTA GGATGTTCAC TTCTTCTCCA CAATGAATGA GTGTCACTAT 60
GACAAGCACA TββACTTTTT TTATAATAβG AGCAACACTG ATACTGTCGA TGACTGGACA 120
6GAACAAAGC TTβTβATTGT TTTGTGTGTT GββACGTTTT TCTGCCTGTT TATTTTTTTT 180
TCTAATTCTC TGGTCATCβC GGCAGTGATC AAAAACAβAA AATTTCATTT CCCCTTCTAC 240
TACCTβTTGG CTAATTTAGC TGCTGCCGAT TTCTTCGCTG GAATTGCCTA TGTATTCCTG 300
ATβTTTAACA CAββCCCAGT TTCAAAAACT TTGACTGTCA ACCGCTGGTT TCTCCGTCAβ 360
GGGCTTCTGG ACAGTAGCTT GACTGCTTCC CTCACCAACT TGCTGGTTAT CGCCβTGGAG 420
AGGCACATGT CAATCATGAG GATGCGGGTC CATAGCAACC TβACCAAAAA βAGGGTβACA 480
CTGCTCATTT TGCTTGTCTG GGCCATCGCC ATTTTTATββ GGGCGGTCCC CACACTGGGC 540
TGGAATTβCC TCTGCAACAT CTCTGCCTGC TCTTCCCTGG CCCCCATTTA CAGCAGGAGT 600
TACCTTGTTT TCTGGACAGT GTCCAACCTC ATβGCCTTCC TCATCATββT TβTGβTβTAC 660
CTGCGGATCT ACGTGTACGT CAAGAGGAAA ACCAACGTCT TGTCTCCGCA TACAAGTβGG 720
TCCATCAGCC GCCGGAGGAC ACCCATGAAG CTAATβAAGA CGGTGATGAC TGTCTTAGGG 780 GCGTTTGTGG TATGCTGGAC CCCGGGCCTG GTGGTTCTGC TCCTCGACGG CCTGAACTGC 840
AGGCAGTGTG GCGTGCAGCA TGTGAAAAGG TGGTTCCTGC TGCTCβCGCT GCTCAACTCC 900
GTCGTGAACC CCATCATCTA CTCCTACAAG GACGAGGACA TGTATGGCAC CATGAAGAAG 960
ATβATCTGCT GCTTCTCTCA GGAGAACCCA GAGAGGCGTC CCTCTCGCAT CCCCTCCACA 1020
GTCCTCAGCA GGAGTGACAC AGGCAGCCAG TACATAGAGG ATAGTATTAβ CCAAGGTGCA 1080
GTCTGCAATA AAAGCACTTC CTAAACTCTG GATGCCTCTC GβCCCACCCA GGTGATGACT 1140 GTCTTAGβ
A180 Protein sequence:
Gene name: endothelial differentiation, lysophoεphatidic acid β-protein-coupled receptor, 7
Unigene number: Hε.258583
Probeset Accession ft: NM_012152
Protein Accession #: NP_036284
Signal sequence: none found
Transmembrane domains: 31-53, 66-88, 150-172, 190-211, 239-261, 277-295
Cellular Localization: plasma membrane
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I I I I I I
MNECHYDKHM DFFYNRSNTD TVDDWTGTKL VIVLCVGTFF CLFIFFSNSL VIAAVIKNRK 60
FHFPFYYLLA NLAAADFFAG IAYVFLMFNT GPVSKTLTVN RWFLRQGLLD SSLTASLTNL 120
LVIAVERHMS IMRMRVHSNL TKKRVTLLIL LVWAIAIFMG AVPTLGWNCL CNISACSSLA 180
PIYSRSYLVF WTVSNLMAFL IMVWYLRIY VYVKRKTNVL SPHTSGSISR RRTPMKLMKT 240
VMTVLGAFW CWTPGLWLL LDGLNCRQCG VQHVKRWFLL LALLNSWNP II SYKDEDM 300 YGTMKKMICC FSQENPERRP SRIPSTVLSR SDTGSQYIED SISQβAVCNK STS
A181 DNA SEQUENCE
Gene name : ESTs
Unigene number: Hs .162859
Probeset Accession ft : AA569531
Nucleic Acid Accession ft : AA569531
Coding sequence : 1-504 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
ATGACCTACA GTTACTCATT TTTCAGGCCT GAGTTGATCG TTAATCATCT TAATTATGTT 60
CATTCTGAAG CCAACAGGAG AACCAAGACC AAAACTTTAT TGTCTCTCCT TTCATTTCTT 120
GATGAAACCT CTGGACTAAG CACACATCTT CCTTGTTTAT CTCTCTCAAA GGAGTGTGGA 180
GTβCTTCATC TGGACATCCA CGGGAAGAAG GAAGACATβA βAATCACCCA ACAGTCTTCC 240
CAGCTATACC TGTGGGACAT GGGTGGTTTT ACAATATTTA AGAACCTGTG GATGAβCCTC 300
ATACCCAβAβ GGAACAAACG CTCCCCAAAA AGAGTTACAG AAACCATCCT GAGAGATTTT 360
AAGCAGAAβC AAAGTTCAAA GATCCAAGAβ βAGAGACGAA GAGAGTCTGC AGGACCAAAC 420
CTCTCTTCAT TCTGGTTTGT GGβGAATGCT GGAAGAGGAG ACAGGCCCCA GATTTGGβCA 480
GGAAGTAAAC AGTTTTCAGG CTGAGGCCAA TCTGAGCAGG AACATTCCAA TATTTCTTCA 540
GCTACGTTGT CCCAGCACTT CACTGβTTAA CCTTTTATGT CCACCATTTG TGGATTTCAC 600
AGCTACTTβT CAATGGTGAA TATTGATCAT CATCATTATC TACTGAGCTG CTACCATATC 660
CCAGCTACTC CTTβCATGTT GTTCATTATT TTCTCAACAC TCAGCATATT TGCAATATGT 720
TATGTAATAT CACAGACAAG GAAACTGAAC GCAβAAATβT TTTATTTCTT GCCAAACATC 780
ACATGAGGAT GAACAATGAA ACCGATTTGA AACCAGGATT GTCTβATTCC AACATCTCTG 840 GGTCCTTTTT CACTCTGATA TGCTGCAATT AAAAAGCCAT TTCTAAGACT GT
A182 Protein sequence:
Gene name: ESTs
Unigene number: Hs.162859
Probeset Accession ft: AA569531
Protein Accession ft: none found
Signal sequence: 1-46
Transmembrane domains : none found
Cellular Localization: not determined
1 11 21 31 41 51
I I I I I I
MTYSYSFFRP ELIVNHLNYV HSEANRRTKT KTLLSLLSFL DETSGLSTHL PCLSLSKECG 60 VLHLDIHGKK EDMRITQQSS QLYLWDMGβF TIFKNLWMSL IPRGNKRSPK RVTETILRDF 120 KQKQSSKIQE ERRRESAGPN LSSFWFVGNA GRβDRPQIWA GSKQFSG
A183 DNA SEQUENCE
Gene name: ESTs
Unigene number: Hs.179809
Probeset Accession ft: N95796
Nucleic Acid Accession ft: XM_050197
Coding sequence: 310-1971 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
TCACACGTGC CAAGGGβCTG GCTCAGCGGA ACCAβCCTGC ACGCGCTGGC TCCGGGTGAC 60
AGCCGCGCGC CTCGGCCAGβ ATCTβAβTGA TGAGACGTGT CCCCACTGAG GTGCCCCACA 120
GCAGCAGGTG TTGAGCATGG GCTGAGAAGC TGβACCGGCA CCAAAGGGCT GGCAβAAATG 180
GβCβCCTGGC TGATTCCTAG GCAGTTGGCG GCAβCAAββA GGAGAGGCCG CAGCTTCTGG 240
AGCAGAGCCG AGACGAAGCA GTTCTGGAGT GCCTGAACGG CCCCCTGAGC CCTACCCGCC 300 TGGCCCACTA_TGGTCCAGAG GCTGTGGGTG AGCCGCCTGC TGCGGCACCG GAAAGCCCAG 360
CTCTTGCTGG TCAACCTGCT AACCTTTGGC CTGGAGGTGT GTTTββCCGC AGβCATCACC 420
TATGTGCCGC CTCTGCTGCT GGAAβTGGGG GTAGAGGAGA AGTTCATGAC CATββTβCTβ 480
GGCATTGGTC CAGTGCTGββ CCTGβTCTβT GTCCCGCTCC TAGGCTCAGC CAβTβACCAC 540
TGGCGTGβAC βCTATGGCCG CCGCCGGCCC TTCATCTGGβ CACTGTCCTT GGGCATCCTβ 600
CTGAGCCTCT TTCTCATCCC AAGGGCCGGC TGGCTAGCAG GGCTβCTβTG CCCGGATCCC 660
AGGCCCCTGG AβCTGGCACT GCTCATCCTG GGCGTGGβGC TGCTGGACTT CTGTββCCAβ 720
GTGTβCTTCA CTCCACTGGA GGCCCTGCTC TCTGACCTCT TCCGGGACCC ββACCACTGT 780
CCCCAGGCCT ACTCTGTCTA TGCCTTCATG ATCAGTCTTG GGββCTβCCT GGGCTACCTC 840
CTGCCTGCCA TTGACTGGGA CACCAGTGCC CTGGCCCCCT ACCTGββCAC CCAGGAGGAG 900
TGCCTCTTTG βCCTGCTCAC CCTCATCTTC CTCACCTGCβ TAGCAGCCAC ACTGCTGβTG 960
GCTGAGGAGG CAGCGCTGGG CCCCACCGAG CCAGCAGAAG GGCTGTCGGC CCCCTCCTTG 1020
TCGCCCCACT βCTβTCCATG CCGGβCCCGC TTGGCTTTCC GGAACCTGGG CGCCCTGCTT 1080
CCCCGGCTGC ACCAGCTGTG CTGCCGCATG CCCCGCACCC TGCGCCGGCT CTTCGTGβCT 1140
GAGCTGTGCA GCTGGATGGC ACTCATGACC TTCACGCTGT TTTACACGGA TTTCβTGGGC 1200
GAGGGGCTGT ACCAGGGCGT GCCCAGAGCT GAGCCGGGCA CCGAGGCCCG GAGACACTAT 1260
GATGAAGGCG TTCGGATGGG CAGCCTGGGG CTGTTCCTGC AGTGCGCCAT CTCCCTββTC 1320
TTCTCTCTGG TCATGβACCβ GCTGGTβCAβ C6ATTCGGCA CTCGAGCAGT CTATTTGGCC 1380
AGTGTGGCAC CTTTCCCTGT GGCTCCCGGT GCCACATGCC TβTCCCACAG TGTGGCCGTG 1440
GTGACAGCTT CAβCCGCCCT CACCGGGTTC ACCTTCTCAG CCCTGCAGAT CCTGCCCTAC 1500
ACACTGGCCT CCCTCTACCA CCGGGAGAAG CAGGTGTTCC TGCCCAAATA CCGAGGGGAC 1560
ACTGGAGGTG CTAGCAGTGA GGACAGCCTG ATGACCAGCT TCCTGCCAGG CCCTAAGCCT 1620
GGAGCTCCCT TCCCTAATGG ACACGTGGGT GCTGGAGGCA GTGGCCTGCT CCCACCTCCA 1680
CCCGCGCTCT GCGGGGCCTC TGCCTGTβAT GTCTCCβTAC GTGTGGTGGT GGGTβAβCCC 1740
ACCGAGGCCA GGGTGGTTCC GGGCCGGGGC ATCTGCCTGG ACCTCGCCAT CCTGGATAGT 1800
GCCTTCCTGC TβTCCCAGGT GGCCCCATCC CTGTTTATGG GCTCCATTGT CCAGCTCAGC 1860
CAβTCTβTCA CTGCCTATAT ββTβTCTGCC GCAGGCCTGG GTCTGGTCβC CATTTACTTT 1920
GCTACACAGG TAGTATTTGA CAAGAGCGAC TTGGCCAAAT ACTCAGCGTA _GAAAACTTCC 1980
AGCACATTGG GGTGGAGGGC CTGCCTCACT GGGTCCCAGC TCCCCβCTCC TGTTAGCCCC 2040
ATGGGGCTGC CGGGCTβGCC GCCAGTTTCT GTTGCTGCCA AAGTAATGTG GCTCTCTGCT 2100
GCCACCCTGT GCTβCTGAGβ TGCβTAβCTG CACAGCTGGG GGCTGGβGCG TCCCTCTCCT 2160
CTCTCCCCAβ TCTCTAββGC TGCCTβACTG GAGGCCTTCC AAββGGGTTT CAGTCTGGAC 2220
TTATACAβGG AGGCCAGAAβ GGCTCCATGC ACTGGAATGC GGGGACTCTG CAGGTGGATT 2280
ACCCAGGCTC AGβGTTAACA GCTAGCCTCC TAGTTGAβAC ACACCTAGAG AAGGGTTTTT 2340
GGGAGCTGAA TAAACTCAGT CACCTGGTTT CCCATCTCTA AGCCCCTTAA CCTGCAGCTT 2400
CGTTTAATGT AGCTCTTGCA TGGGAGTTTC TAGGATβAAA CACTCCTCCA TGGGATTTGA 2460
ACATATGAAA GTTATTTGTA GGGGAAGAGT CCTGAGβββC AACACACAAG AACCAGβTCC 2520
CCTCAGCCCC ACAGGCACTG GTCTTTTTTG CTNGANTCCA CCCCCCCCCT CTTTACCCTT 2580 TT
A184 Protein sequence : Gene name: ESTs Unigene number: Hε .179809 Probeset Accession ft : N95796 Protein Accession it -. XP_050197 Signal sequence : none Transmembrane domains : 21-43 , 53-75, 90- 112 , 125-147, 160-182 , 199-221, 323-345 , 350-372 , 379-401 Cellular Localization: plasma membrane
11 21 31 41 51
I I I I I
MVQRLWVSRL LRHRKAQLLL VNLLTFGLEV CLAAGITYVP PLLLEVβVEE KFMTMVLGIG 60 PVLGLVCVPL LGSASDHWRG RYGRRRPFIW ALSLGILLSL FLIPRAβWLA GLLCPDPRPL 120 ELALLILGVG LLDFCGQVCF TPLEALLSDL FRDPDHCRQA YSVYAFMISL GGCLGYLLPA 180 IDWDTSALAP YLGTQEECLF GLLTLIFLTC VAATLLVAEE AALGPTEPAE GLSAPSLSPH 240 CCPCRARLAF RNLGALLPRL HQLCCRMPRT LRRLFVAELC SWMALMTFTL FYTDFVGEβL 300 YQGVPRAEPG TEARRHYDEβ VRMGSLGLFL QCAISLVFSL VMDRLVQRFG TRAVYLASVA 360 AFPVAAGATC LSHSVAWTA SAALTGFTFS ALQILPYTLA SLYHREKQVF LPKYRGDTβG 420 ASSEDSLMTS FLPGPKPGAP FPNGHVGAββ SGLLPPPPAL CGASACDVSV RVWGEPTEA 480 RWPGRGICL DLAILDSAFL LSQVAPSLFM GSIVQLSQSV TAYMVSAAGL βLVAIYFATQ 540 WFDKSDLAK YSA
A185 DNA SEQUENCE
Gene name: ESTs
Unigene number: Hs.11260
Probeset Accession #: R73640
Nucleic Acid Accession #: AK002126
Coding sequence: 1-1593 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I
ATGGTTCGCC GβGGGCTGCT TβCGTGGATT TCCCGGβTββ TGGTTTTGCT GGTβCTCCTC 60 TGCTGTGCTA TCTCTGTCCT GTACATGTTG GCCTGCACCC CAAAAGGTGA CβAββAβCAG 120 CTGGCACTGC CCAGGGCCAA CAGCCCCACG GβGAAGGAGG GGTACCAGGC CβTCCTTCAG 180 GAGTGGGAGG AGCAGCACCG CAACTACβTβ AGCAGCCTGA AGCGGCAGAT CGCACAβCTC 240 AAGGAGGAGC TGCAGGAβAG GAGTGAGCAβ CTCAGGAATG GGCAGTACCA AGCCAGCGAT 300 GCTGCTGGCC TGββTCTGGA CAGGAGCCCC CCAGAGAAAA CCCAGGCCβA CCTCCTGGCC 360 TTCCTGCACT CGCAGGTGGA CAAGGCAGAG GTGAATGCTG βCβTCAAGCT GGCCACAGAG 420 TATGCAGCAβ TGCCTTTCGA TAGCTTTACT CTACAGAAGβ TGTACCAGCT GGAβACTGGC 480 CTTACCCGCC ACCCCGAGGA βAAβCCTGTG AGGAA6GACA AGCGGGATGA GTTGGTGGAA 540 GCCATTGAAT CAGCCTTGGA βACCCTGAAC AATCCTGCAG AGAACAGCCC CAATCACCGT 600 CCTTACACGG CCTCTGATTT CATACAAGGβ ATCTACCGAA CAGAAAGGGA CAAAGβGACA 660 TTGTATβAGC TCACCTTCAA AGGGGACCAC AAACACGAAT TCAAACGGCT CATCTTATTT 720 CGACCATTCG GCCCCATCAT GAAAGTGAAA AATGAAAAGC TCAACATGGC CAACACβCTT 780 ATCAATβTTA TCGTGCCTCT AβCAAAAAGG GTGGACAAGT TCCGGCAGTT CATβCAGAAT 840 TTCAGGGAGA TGTGCATTGA GCAGGATGGG AGAGTCCATC TCACTGTTGT TTACTTTGGG 900 AAAGAAGAAA TAAATGAAGT CAAAGβAATA CTTGAAAACA CTTCCAAAGC TGCCAACTTC 960 AGGAACTTTA CCTTCATCCA GCTGAATGGA GAATTTTCTC GGβGAAAGGG ACTTGATβTT 1020 GGAGCCCGCT TCTGGAAβββ AAGCAACGTC CTTCTCTTTT TCTGTβATGT GGACATCTAC 1080 TTCACATCTG AATTCCTCAA TACGTGTAββ CTβAATACAC AGCCAββGAA GAAGGTATTT 1140 TATCCAGTTC TTTTCAβTCA βTACAATCCT GGCATAATAT ACGGCCACCA TGATGCAGTC 1200 CCTCCCTTGG AACAGCAGCT GGTCATAAAG AAGGAAACTG GATTTTGGAG AGACTTTGGA 1260 TTTGGGATGA CGTGTCAGTA TCββTCAGAC TTCATCAATA TAGGTGGGTT TGATCTGGAC 1320 ATCAAAGGCT GβGGCGβAGA GGATGTGCAC CTTTATCGCA AGTATCTCCA CAGCAACCTC 1380 ATAGTGGTAC GGACβCCTβT GCGAGGACTC TTCCACCTCT GGCATGAGAA GCGCTGCATG 1440 GACGAGCTGA CCCCCGAGCA GTACAAGATG TβCATβCAβT CCAAGGCCAT GAACGAGGCA 1500 TCCCACGGCC AGCTGββCAT GCTGβTβTTC AGGCACGAβA TAGAGGCTCA CCTTCGCAAA 1560 CAGAAACAGA AGACAAGTAβ CAAAAAAACA TGA
A186 Protein sequence: Gene name: ESTs Unigene number: Hs.11260 Probeset Acceεsion #: R73640 Protein Acceεεion #: NP_060841 Signal sequence: 1-26 Transmembrane domains: none found Cellular Localization: not determined
11 21 31 41 51
I I I I I
MVRRGLLAWI SRVWLLVLL CCAISVLYML ACTPKGDEEQ LALPRANSPT GKEGYQAVLQ 60 EWEEQHRNYV SSLKRQIAQL KEELQERSEQ LRNGQYQASD AAGLGLDRSP PEKTQADLLA 120 FLHSQVDKAE VNAGVKLATE YAAVPFDSFT LQKVYQLETG LTRHPEEKPV RKDKRDELVE 180 AIESALETLN NPAENSPNHR PYTASDFIEG lYRTERDKGT LYELTFKGDH KHEFKRLILF 240 RPFGPIMKVK NEKLNMANTL INVIVPLAKR VDKFRQFMQN FREMCIEQDG RVHLTWYFG 300 KEEINEVKGI LENTSKAANF RNFTFIQLNG EFSRGKGLDV GARFWKGSNV LLFFCDVDIY 360 FTSEFLNTCR LNTQPGKKVF YPVLFSQYNP GIIYGHHDAV PPLEQQLVIK KETGFWRDFβ 420 FGMTCQYRSD FINIGGFDLD IKGWGGEDVH LYRKYLHSNL IWRTPVRGL FHLWHEKRCM 480 DELTPEQYKM CMQSKAMNEA SHGQLGMLVF RHEIEAHLRK QKQKTSSKKT
A187 DNA SEQUENCE βene name: ATPase, Ca++ transporting, type 2C, member 1
Unigene number: Hs.106778
Probeset Accession ft: N51919
Nucleic Acid Accession it: AF189723
Coding εequence: 1-2712 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I I
ATGATTCCT TATTGACATC AAAAAAAGCA AGTGAATTAC CAGTCAGTGA AGTTGCAAGC 60 ATTCTCCAAβ CTGATCTTCA GAATGGTCTA AACAAATGTG AAGTTAGTCA TAGGCGAGCC 120 TTTCATββCT GGAATGAGTT TGATATTAGT GAAGATGAGC CACTGTβGAA GAAGTATATT 180 TCTCAGTTTA AAAATCCCCT TATTATGCTG CTTCTGGCTT CTGCAGTCAT CAGTGTTTTA 240 ATGCATCAGT TTGATGATGC CGTCAGTATC ACTGTGGCAA TACTTATCGT TGTTACAGTT 300 GCCTTTGTTC AGβAATATCG TTCAGAAAAA TCTCTTGAAG AATTGAGTAA ACTTGTGCCA 360 CCAGAATGCC ATTGTGTGCβ TGAAGβAAAA TTGGAβCATA CACTTGCCCG AGACTTGGTT 420 CCAGGTGATA CAGTTTGCCT TTCTGTTGGG GATAGAGTTC CTGCTGACTT ACGCTTGTTT 480 GAGGCTβTGG ATCTTTCCAT TGATβAGTCC ACCTTGACAG GTGAGACAAC GCCTTGTTCT 540 AAGGTGACAG CTCCTCAGCC AGCTGCAACT AATGGAGATC TTGCATCGAG AAGTAACATT 600 GCCTTTATGβ βAACACTGGT CAGATGTGGC AAAGCAAAGG GTGTTGTCAT TGGAACAGGA 660 GAAAATTCTG AATTTGβGGA GGTTTTTAAA ATGATGCAAG CAGAAGAGGC ACCAAAAACC 720 CCTCTGCAGA AGAGCATGβA CCTCTTAGGA AAACAACTTT CCTTTTACTC CTTTG6TATA 780 ATAGGAATCA TCATGTTβGT TGGCTGGTTA CTGGGAAAAG ATATCCTGGA AATGTTTACT 840 ATTAGTGTAA GTTTGβCTGT AGCAGCAATT CCTGAAGGTC TCCCCATTGT GGTCACAGTG 900 ACGCTAGCTC TTGGTGTTAT GAGAATGGTG AAGAAAAGGG CCATTGTGAA AAAGCTGCCT 960 ATTGTTGAAA CTCTGββCTG CTGTAATGTG ATTTGTTCAG ATAAAACTGG AACACTGACG 1020 AAGAATGAAA TβACTβTTAC TCACATATTT ACTTCAGATG GTCTGCATGC TGAGGTTACT 1080 GGAGTTββCT ATAATCAATT TGGGGAAGTG ATTGTTGATG GTGATGTTGT TCATGGATTC 1140 TATAACCCAG CTGTTAGCAG AATTGTTGAG GCGGGCTGTG TGTGCAATGA TGCTGTAATT 1200 AGAAACAATA CTCTAATGGG GAAGCCAACA GAAGGGGCCT TAATTGCTCT TGCAATGAAG 1260 ATGGGTCTTG ATGGACTTCA ACAAGACTAC ATCAGAAAAG CTGAATACCC TTTTAGCTCT 1320 GAGCAAAAGT GGATGGCTGT TAAGTGTGTA CACCGAACAC AGCAGGACAG ACCAGAGATT 1380 TGTTTTATGA AAGGTGCTTA CGAACAAGTA ATTAAGTACT GTACTACATA CCAGAGCAAA 1440 GGGCAGACCT TGACACTTAC TCAGCAGCAG AGAGATGTGT ACCAACAAβA βAAβGCACGC 1500 ATGGβCTCAβ CGGGACTCAC AGTTCTTGCT TTGGCTTCTG βTCCTβAACT GGGACAGCTG 1560 ACATTTCTTG GCTTGGTGGG AATCATTβAT CCACCTAGAA CTGGTGTGAA AGAAβCTGTT 1620 ACAACACTCA TTGCCTCAGβ AGTATCAATA AAAATGATTA CTGβAGATTC ACAGGAGACT 1680 GCAGTTGCAA TCGCCAGTCG TCTGββATTG TATTCCAAAA CTTCCCAGTC AGTCTCAGGA 1740 GAAGAAATAβ ATGCAATGβA TGTTCAGCAG CTTTCACAAA TAβTACCAAA GGTTGCAGTA 1800 TTTTACAGAG CTA6CCCAAG GCACAAβATG AAAATTATTA AGTCGCTACA GAAGAACββT 1860 TCAGTTGTAG CCATGACAGβ AGATGGAβTA AATGATβCAG TTGCTCTGAA GGCTGCAGAC 1920 ATTGβAGTTG CGATGGGCCA GACTGGTACA GATGTTTβCA AAGAGGCAGC AGACATGATC 1980 CTAGTGGATG ATGATTTTCA AACCATAATG TCTGCAATCG AAβAGGGTAA AGGβATTTAT 2040 AATAACATTA AAAATTTCGT TAGATTCCAG CTGAGCACGA GTATAGCAGC ATTAACTTTA 2100
ATCTCATTGG CTACATTAAT βAACTTTCCT AATCCTCTCA ATGCCATGCA GATTTTβTββ 2160
ATCAATATTA TTATGβATGβ ACCCCCAGCT CAGAGCCTTG GAGTAGAACC AβTGGATAAA 2220 βATβTCATTC GTAAACCTCC TCGCAACTGG AAAGACAβCA TTTTGACTAA AAACTTGATA 2280
CTTAAAATAC TTGTTTCATC AATAATCATT GTTTGTGββA CTTTGTTTβT CTTCTGβCβT 2340
GAGCTACGAβ ACAATGTGAT TACACCTCGA GACACAACAA TGACCTTCAC ATβCTTTGTβ 2400
TTTTTTGACA TGTTCAATGC ACTAAGTTCC AGATCCCAGA CCAAGTCTGT GTTTGAGATT 2460
GGACTCTGCA GTAATA6AAT GTTTTGCTAT GCAGTTCTTG GATCCATCAT GGGACAATTA 2520
CTAGTTATTT ACTTTCCTCC GCTTCAGAAG GTTTTTCAGA CTGAGAGCCT AAGCATACTG 2580
GATCTGTTGT TTCTTTTGGG TCTCACCTCA TCAGTGTGCA TAGTGGCAGA AATTATAAAG 2640
AAGGTTGAAA GGAGCAGGGA AAAGATCCAG AAGCATGTTA GTTCGACATC ATCATCTTTT 2700
CTTGAAGTAT GA
A188 Protein sequence: βene name-. ATPase, Ca++ transporting type 2C, member 1 Unigene number: Hs.106778 Probeset Accession ft : N51919 Protein Accesεion ft: AAF27813 Signal sequence : none found Transmembrane domains : 60-82, 86-108, 252-274, 282-304, 757-779, 827-849, 856-878 Pfam domains: Cation ATPase N [6-83] , E1-E2 ATPase [89-324] , Hydrolase [328-649] , Cation ATPase C [744-889] Cellular Localization: not determined 1 11 21 31 41 51
I I I I I I
MIPVLTSKKA SELPVSEVAS ILQADLQNGL NKCEVSHRRA FHGWNEFDIS EDEPLWKKYI 60
SQFKNPLIML LLASAVISVL MHQFDDAVSI TVAILIWTV AFVQEYRSEK SLEELSKLVP 120
PECHCVREGK LEHTLARDLV PGDTVCLSVG DRVPADLRLF EAVDLSIDES SLTGETTPCS 180 KVTAPQPAAT NGDLASRSNI AFMGTLVRCG KAKG IGTG ENSEFGEVFK MMQAEEAPKT 240
PLQKSMDLLG KQLSFYSFGI IGIIMLVGWL LGKDILEMFT ISVSLAVAAI PEGLPIWTV 300
TLALGVMRMV KKRAIVKKLP IVETLβCCNV ICSDKTβTLT KNEMTVTHIF TSDGLHAEVT 360
GVGYNQFGEV IVDGDWHGF YNPAVSRIVE AGCVCNDAVI RNNTLMGKPT EGALIALAMK 420
MGLDGLQQDY IRKAEYPFSS EQKWMAVKCV HRTQQDRPEI CFMKGAYEQV IKYCTTYQSK 480 GQTLTLTQQQ RDVYQQEKAR MGSAGLRVLA LASGPEL6QL TFLGLVGIID PPRTGVKEAV 540
TTLIASGVSI KMITGDSQET AVAIASRLGL YSKTSQSVSG EEIDAMDVQQ LSQIVPKVAV 600
FYRASPRHKM KIIKSLQKNG SWAMTGDGV NDAVALKAAD IGVAMGQTGT DVCKEAADMI 660
LVDDDFQTIM SAIEEGKGIY NNIKNFVRFQ LSTSIAALTL ISLATLMNFP NPLNAMQILW 720
INIIMDGPPA QSLGVEPVDK DVIRKPPRNW KDSILTKNLI LKILVSSIII VCGTLFVFWR 780 ELRDNVITPR DTTMTFTCFV FFDMFNALSS RSQTKSVFEI GLCSNRMFCY AVLGSIMGQL 840
LVIYFPPLQK VFQTESLSIL DLLFLLGLTS SVCIVAEIIK KVERSREKIQ KHVSSTSSSF 900 LEV
A189 DNA SEQUENCE
Gene name: ESTs
Unigene number: Hs.293185
Probeset Accession #: N62096
Nucleic Acid Accession ft: N62096
Coding sequence: 1-1284 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
ATGGGCTACC AGAGGCAGGA GCCTGTCATC CCGCCGCAβA βAGGATTGCC TTATTCAATG 60
AAGCAAGCTG GGTTTCCTTT GGGAATATTG CTTTTATTCT GGGTTTCATA TGTTACAGAC 120
TTTTCCCTTG TTTTATTGAT AAAAGGAGGG GCCCTCTCTG GAACAGATAC CTACCAGTCT 180
TTGGTCAATA AAACTTTCGG CTTTCCAGGG TATCTGCTCC TCTCTGTTCT TCAGTTTTTG 240
TATCCTTTTA TAβCAATβAT AAGTTACAAT ATAATAGCTG GAGATACTTT GAGCAAAGTT 300
TTTCAAAGAA TCCCAGGAGT TGATCCTGAA AACGTGTTTA TTGGTCGCCA CTTCATTATT 360
GGACTTTCCA CAGTTACCTT TACTCTGCCT TTATCCTTGT ACCGAAATAT AGCAAAGCTT 420
GGAAAGGTCT CCCTCATCTC TACAGGTTTA ACAACTCTβA TTCTTGGAAT TGTAATGGCA 480
AGGGCAATTT CACTGGGTCC ACACATACCA AAAACAGAAG ACGCTTGGGT ATTTβCAAAG 540
CCCAATGCCA TTCAAβCGGT CGGGGTTATG TCTTTTGCAT TTATTTβCCA CCATAACTCC 600
TTCTTAβTTT ACAGTTCTCT AGAAGAACCC ACAGTAGCTA AGTGGTCCCG CCTTATCCAT 660
ATGTCCATC6 TGATTTCTGT ATTTATCTGT ATATTCTTTG CTACATGTGG ATACTTGACA 720
TTTACTGGCT TCACCCAAGG GGACTTATTT GAAAATTACT GCAGAAATGA TβACCTGGTA 780
ACATTTGβAA GATTTTGTTA TGβTβTCACT GTCATTTTGA CATACCCTAT GGAATGCTTT 840
GTGACAAGAG AGGTAATTGC CAATGTGTTT TTTGGTGGβA ATCTTTCATC GGTTTTCCAC 900
ATTGTTGTAA CAGTGATGGT CATCACTGTA GCCACGCTTG TGTCATTGCT βATTGATTGC 960
CTCGGGATAG TTCTAGAACT CAATGGTGTG CTCTGTGCAA CTCCCCTCAT TTTTATCATT 1020
CCATCAβCCT βTTATCTGAA ACTGTCTGAA GAACCAAGGA CACACTCCGA TAAGATTATG 1080
TCTTGTGTCA TGCTTCCCAT TGGTGCTGTG GTGATGGTTT TTGGATTCGT CATGGCTATT 1140
ACAAATACTC AAGACTGCAC CCATGGGCAG GAAATβTTCT ACTGCTTTCC TGACAATTTC 1200
TCTCTCACAA ATACCTCAGA GTCTCATGTT CAGCAGACAA CACAACTTTC TACTTTAAAT 1260
ATTAGTATCT TTCAACTCGA GTAA
A190 Protein εequence:
Gene name: ESTs
Unigene number: Hs.293185
Probeset Accession #: N62096
Protein Accession ft : none found
Signal sequence : none found
Transmembrane domainε: 28-50, 66-88-112-134, 142-164, 217-239, 260-282, 298-320, 327-348, 359-381 Cellular Localization: plasma membrane
1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQRGLPYSM KQAGFPLGIL LLFWVSYVTD FSLVLLIKGG ALSGTDTYQS 60
LVNKTFGFPβ YLLLSVLQFL YPFIAMISYN IIAβDTLSKV FQRIPGVDPE NVFIGRHFII 120
GLSTVTFTLP LSLYRNIAKL GKVSLISTGL TTLILGIVMA RAISLGPHIP KTEDAWVFAK 180
PNAIQAVβVM SFAFICHHNS FLVYSSLEEP TVAKWSRLIH MSIVISVFIC IFFATCβYLT 240 0 FTGFTQGDLF ENYCRNDDLV TFGRFCYGVT VILTYPMECF VTREVIANVF FGGNLSSVFH 300
IWTVMVITV ATLVSLLIDC LGIVLELNβV LCATPLIFII PSACYLKLSE EPRTHSDKIM 360
SCVMLPIGAV VMVFGFVMAI TNTQDCTHGQ EMFYCFPDNF SLTNTSESHV QQTTQLSTLN 420 ISIFQLE 5 A191 DNA SEQUENCE
Gene name: ESTs
Unigene number: Hs.293185
Probeset Accession #: N62096
Nucleic Acid Accession ft: N62096 0 Coding sequence: 1-1203 (underlined sequences correspond to start and εtop codons)
1 11 21 31 41 51
I I I I I I 5 ATGGGCTACC AβAβGCAβGA GCCTGTCATC CCGCCGCAGT TTTCCCTTGT TTTATTGATA 60
AAAβGAGGGG CCCTCTCTGβ AACAGATACC TACCAGTCTT TGGTCAATAA AACTTTCGGC 120
TTTCCAGββT ATCTβCTCCT CTCTGTTCTT CAGTTTTTGT ATCCTTTTAT AGCAATGATA 180
AGTTACAATA TAATAGCTGG AGATACTTTG AGCAAAβTTT TTCAAAGAAT CCCAGGAGTT 240
GATCCTGAAA ACGTGTTTAT TGGTCGCCAC TTCATTATTG GACTTTCCAC AGTTACCTTT 300 0 ACTCTGCCTT TATCCTTGTA CCβAAATATA GCAAAGCTTβ GAAAββTCTC CCTCATCTCT 360
ACAGGTTTAA CAACTCTGAT TCTTGGAATT GTAATGGCAA GGβCAATTTC ACTGGGTCCA 420
CACATACCAA AAACAGAAGA CβCTTGGGTA TTTGCAAAGC CCAATCCCAT TCAAGCGGTC 480
GGGGTTATβT CTTTTGCATT TATTTGCCAC CATAACTCCT TCTTAGTTTA CAGTTCTCTA 540
GAAGAACCCA CAGTAGCTAA GTGGTCCCGC CTTATCCATA TGTCCATCGT GATTTCTGTA 600 5 TTTATCTGTA TATTCTTTGC TACATGTGGA TACTTGACAT TTACTGGCTT CACCCAAGGG 660
GACTTATTTG AAAATTACTG CAGAAATGAT GACCTββTAA CATTTGGAAG ATTTTGTTAT 720
GGTGTCACTG TCATTTTGAC ATACCCTATG GAATGCTTTβ TβACAAGAGA GGTAATTGCC 780
AATGTGTTTT TTβGTGGGAA TCTTTCATCG GTTTTCCACA TTGTTGTAAC AGTGATGGTC 840
ATCACTGTAG CCACGCTTGT GTCATTGCTG ATTGATTGCC TCβGGATAβT TCTAGAACTC 900 0 AATGGTGTGC TCTGTGCAAC TCCCCTCATT TTTATCATTC CATCAGCCTG TTATCTβAAA 960
CTβTCTGAAG AACCAAβGAC ACACTCCGAT AAGATTATGT CTTGTGTCAT GCTTCCCATT 1020
GGTβCTβTβG TGATGGTTTT TGGATTCGTC ATGGCTATTA CAAATACTCA AGACTGCACC 1080
CATGGβCAββ AAATGTTCTA CTGCTTTCCT GACAATTTCT CTCTCACAAA TACCTCAGAβ 1140
TCTCATGTTC AGCAGACAAC ACAACTTTCT ACTTTAAATA TTAGTATCTT TCAACTCGAβ 1200
45 TAA
A192 Protein sequence: Gene name: ESTs D ) Unigene number: Hs.293185
Probeset Accession ft: N62096 Protein Accession ft: none found Signal sequence: 1-26 _ _ Transmembrane domains : 45-61, 92-108, 117-132, 191-207, 274-290, 297-313, 335-351 DD Cellular Localization: plasma membrane
1 11 21 31 41 51
60 I I I I I I
MGYQRQEPVI PPQFSLVLLI KGGALSGTDT YQSLVNKTFG FPβYLLLSVL QFLYPFIAMI 60
SYNIIAβDTL SKVFQRIPβV DPENVFIGRH FIIGLSTVTF TLPLSLYRNI AKLGKVSLIS 120
TGLTTLILβl VMARAISLβP HIPKTEDAWV FAKPNAIQAV GVMSFAFICH HNSFLVYSSL 180
EEPTVAKWSR LIHMSIVISV FICIFFATCG YLTFTGFTQG DLFENYCRND DLVTFGRFCY 240
GVTVILTYPM ECFVTREVIA NVFFGGNLSS VFHIWTVMV ITVATLVSLL IDCLGIVLEL 300
65 NGVLCATPLI FIIPSACYLK LSEEPRTHSD KIMSCVMLPI GAWMVFGFV MAITNTQDCT 360
HGQEMFYCFP DNFSLTNTSE SHVQQTTQLS TLNISIFQLE
A193 DNA SEQUENCE
Gene name: ESTs
70 Unigene number: Hs.293185
Probeset Accession ft: N62096
Nucleic Acid Accesεion ft: N62096
Coding εequence: 1-1140 (underlined sequences correspond to start and stop codons)
75
1 11 21 31 41 51
I I I I I I
ATGGGCTACC AGAβGCAGβA βCCTβTCATC CCβCCGCAGG TCAATAAAAC TTTCGGCTTT 60
CCA6GGTATC TGCTCCTCTC TGTTCTTCAG TTTTTGTATC CTTTTATAGC AATGATAAβT 120
80 TACAATATAA TAβCTGGAGA TACTTTGAGC AAAGTTTTTC AAAGAATCCC AGGAGTTGAT 180
CCTGAAAACG TβTTTATTGβ TCCCCACTTC ATTATTGGAC TTTCCACAβT TACCTTTACT 240
CTGCCTTTAT CCTTGTACCG AAATATAGCA AAGCTTββAA AGGTCTCCCT CATCTCTACA 300
GGTTTAACAA CTCTβATTCT TGGAATTGTA ATGGCAAββG CAATTTCACT GGGTCCACAC 360
ATACCAAAAA CAβAAβACβC TTGGβTATTT GCAAAGCCCA ATGCCATTCA AGCGGTCGGG 420 GTTATGTCTT TTGCATTTAT TTGCCACCAT AACTCCTTCT TAGTTTACAG TTCTCTAGAA 480
GAACCCACAG TAGCTAAGTG GTCCCGCCTT ATCCATATGT CCATCGTGAT TTCTGTATTT 540
ATCTβTATAT TCTTTGCTAC ATGTGGATAC TTGACATTTA CTGGCTTCAC CCAAβGGGAC 600
TTATTTGAAA ATTACTGCAG AAATGATGAC CTGGTAACAT TTG6AAGATT TTGTTATGGT 660
GTCACTGTCA TTTTGACATA CCCTATGGAA TGCTTTGTβA CAAβAβAGGT AATTGCCAAT 720
GTGTTTTTTG βTβββAATCT TTCATCβGTT TTCCACATTG TTGTAACAGT GATGGTCATC 780
ACTGTAGCCA CGCTTGTGTC ATTGCTGATT GATTβCCTCG GβATAβTTCT AGAACTCAAT 840
GGTGTβCTCT GTGCAACTCC CCTCATTTTT ATCATTCCAT CAGCCTGTTA TCTGAAACTG 900
TCTGAAβAAC CAAβGACACA CTCCGATAAG ATTATβTCTT GTGTCATGCT TCCCATTGGT 960 0 GCTGTGGTGA TGGTTTTTGG ATTCGTCATG GCTATTACAA ATACTCAAGA CTβCACCCAT 1020
GβGCAGGAAA TGTTCTACTG CTTTCCTGAC AATTTCTCTC TCACAAATAC CTCAGAGTCT 1080 CATGTTCAGC AGACAACACA ACTTTCTACT TTAAATATTA GTATCTTTCA ACTCGAGTAA 5 A194 Protein sequence Gene name ESTs Unigene number Hs 293185 Probeset Accession ^ N62096 Protein Accession it none found 0 Signal sequence none found Transmembrane domains 24-40, 70-86, 95-111, 171-186, 253-269, 276-292, 314-330 Cellular Localization plasma membrane 5 1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQVNKTFGF PGYLLLSVLQ FLYPFIAMIS YNIIAGDTLS KVFQRIPGVD 60
PENVFIGRHF IlβLSTVTFT LPLSLYRNIA KLGKVSLIST GLTTLILGIV MARAISLGPH 120
IPKTEDAWVF AKPNAIQAVG VMSFAFICHH NSFLVYSSLE EPTVAKWSRL IHMSIVISVF 180 0 ICIFFATCGY LTFTGFTQGD LFENYCRNDD LVTFCRFCYG VTVILTYPME CFVTREVIAN 240
VFFGGNLSSV FHIWTVMVI TVATLVSLLI DCLGIVLELN GVLCATPLIF IIPSACYLKL 300
SEEPRTHSDK IMSCVMLPIG AWMVFGFVM AITNTQDCTH βQEMFYCFPD NFSLTNTSES 360 HVQQTTQLST LNISIFQLE 5
A195 DNA SEQUENCE
Gene name ESTs
Unigene number Hs 293185
Probeset Accession ft N62096 0 Nucleic Acid Accession # N62096
Coding sequence 1-1389 (underlined sequences correspond to start and εtop codons)
21 31 5 I
ATGGGCTACC AGAGGCAGGA GCCTGTCATC CCGCCGCAGA GAGATTTAGA TGACAGAGAA 60
ACCCTTGTTT CTGAACATGA GTATAAAGAβ AAAACCT6TC AGTCTGCTGC TCTTTTTAAT 120
GTTGTCAACT CGATTATAGG ATCTGβTATA ATAGGATTβC CTTATTCAAT GAAβCAAGCT 180
GGGTTTCCTT TGGGAATATT GCTTTTATTC TGGGTTTCAT ATGTTACAGA CTTTTCCCTT 240 0 GTTTTATTGA TAAAAβGAGβ GGCCCTCTCT GGAACAGATA CCTACCAGTC TTTβGTCAAT 300
AAAACTTTCG GCTTTCCAGG GTATCTβCTC CTCTCTGTTC TTCAGTTTTT GTATCCTTTT 360
ATAβCAATGA TAAGTTACAA TATAATAGCT GGAGATACTT TGAGCAAAGT TTTTCAAAβA 420
ATCCCAGGAG TTGATCCTGA AAACGTGTTT ATTGGTCGCC ACTTCATTAT TGGACTTTCC 480
ACAGTTACCT TTACTCTGCC TTTATCCTTG TACCGAAATA TAGCAAAGCT TGGAAAGGTC 540 5 TCCCTCATCT CTACAGGTTT AACAACTCTG ATTCTTGGAA TTGTAATGGC AAGGGCAATT 600
TCACTGGGTC CACACATACC AAAAACAGAA GACGCTTGββ TATTTGCAAA GCCCAATβCC 660
ATTCAAβCGG TCGGGGTTAT GTCTTTTGCA TTTATTTβCC ACCATAACTC CTTCTTAGTT 720
TACAGTTCTC TAGAAβAACC CACAβTAGCT AAGTGGTCCC GCCTTATCCA TATGTCCATC 780
GTGATTTCTG TATTTATCTG TATATTCTTT GCTACATGTG GATACTTGAC ATTTACTGGC 840 0 TTCACCCAAG GGGACTTATT TGAAAATTAC TGCAGAAATG ATGACCTGGT AACATTTGGA 900
AGATTTTGTT ATGGTGTCAC TGTCATTTTG ACATACCCTA TGGAATGCTT TGTGACAAGA 960
GAGGTAATTG CCAATGTGTT TTTTGGTGβG AATCTTTCAT CGGTTTTCCA CATTGTTGTA 1020
ACAβTGATGG TCATCACTGT AGCCACGCTT GTβTCATTGC TGATTGATTG CCTCGGGATA 1080
GTTCTAGAAC TCAATGGTGT GCTCTGTGCA ACTCCCCTCA TTTTTATCAT TCCATCAβCC 1140 5 TGTTATCTGA AACTGTCTGA AGAACCAAGβ ACACACTCCβ ATAAGATTAT GTCTTGTGTC 1200
ATGCTTCCCA TTGGTGCTGT GGTGATGβTT TTTGGATTCG TCATGGCTAT TACAAATACT 1260
CAAGACTGCA CCCATGGGCA GGAAATGTTC TACTGCTTTC CTGACAATTT CTCTCTCACA 1320
AATACCTCAG AGTCTCATGT TCAGCAGACA ACACAACTTT CTACTTTAAA TATTAGTATC 1380 TTTCAATGA 0
A196 Protem sequence Gene name ESTs
Unigene number Hε 293185
/ D Probeεet Acceεsion ft N62096
Protein Acceεsion ft none found
Signal εequence none found
Tranεmembrane domains 37-53, 66-82, 109-125, 155-172, 180-196, 255-271, 338-354, 361-377, 399-415
Cellular Localization plasma membrane
80
1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQRDLDDRE TLVSEHEYKE KTCQSAALFN WNSIIGSGI IGLPYSMKQA 60 GFPLGILLLF WVSYVTDFSL VLLIKGGALS GTDTYQSLVN KTFGFPGYLL LSVLQFLYPF 120
IAMISYNIIA GDTLSKVFQR IPGVDPENVF IGRHFIIβLS TVTFTLPLSL YRNIAKLGKV 180
SLISTGLTTL ILGIVMARAI SLβPHIPKTE DAWVFAKPNA IQAVGVMSFA FICHHNSFLV 240
YΞSLEEPTVA KWSRLIHMSI VISVFICIFF ATCGYLTFTG FTQβDLFENY CRNDDLVTFG 300
RFCYGVTVIL TYPMECFVTR EVIANVFFGG NLSSVFHIW TVMVITVATL VSLLIDCLGI 360
VLELNGVLCA TPLIFIIPSA CYLKLSEEPR THSDKIMSCV MLPIGAWMV FGFVMAITNT 420
QDCTHGQEMF YCFPDNFSLT NTSESHVQQT TQLSTLNISI FQ
A197 DNA SEQUENCE
Gene name • ESTs Unigene number. Hε.31608 Probeset Accession ft: H18836 Nucleic Acid Accession NM.017636 Coding sequence . 1-3501 (underlined εequenceε correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
ATGGAGGATβ CCTTCGGGGC AGCCGTGGTG ACCβTβTGGG ACAGCβATβC ACACACCACG 60
GAβAAβCCCA CCGATGCCTA CββAβAGCTG GACTTCACGG GGGCCGGCCG CAAGCACAGC 120
AATTTCCTCC GβCTCTCTGA CCGAACGGAT CCAGCTGCAG TTTATAGTCT βGTCACACGC 180
ACATGGGGCT TCCβTGCCCC GAACCTβGTG GTβTCAGTGC TGGβββGATC GGGGGGCCCC 240
GTCCTCCAGA CCTββCTβCA GGACCTGCTG CGTCGTGGGC TGβTβCGGGC TGCCCAGAGC 300
ACAGGAGCCT ββATTβTCAC TGGGGGTCTβ CACACGGGCA TCGβCCGGCA TGTTGGTGTβ 360
GCTGTACGGG ACCATCAGAT GGCCAGCACT GGGGGCACCA AGGTGGTGGC CATGGGTβTβ 420 βCCCCCTGGG GTGTGβTCCG GAATAGAGAC ACCCTCATCA ACCCCAAGGG CTCGTTCCCT 480
GCGAGGTACC GGTGGCGCGG TGACCCGGAG βACGGGGTCC AGTTTCCCCT GβACTACAAC 540
TACTCβGCCT TCTTCCTGGT GβACβACGGC ACACACGβCT GCCTGβGGGG CβAGAACCGC 600
TTCCGCTTGC βCCTGGAGTC CTACATCTCA CAGCAGAAGA CGGGCGTβββ AGGGACTGGA 660
ATTGACATCC CTGTCCTGCT CCTCCTGATT GATGGTGATG AGAAGATGTT GACGCGAATA 720
GAGAACGCCA CCCAGGCTCA GCTCCCATGT CTCCTCGTββ CTCGCTCAGG GGβAGCTGCβ 780
CACTGCCTGG CGGAGACCCT GGAAGACACT CTGGCCCCAG GGAGTGGGGβ AGCCAββCAA 840 eβCGAAGCCC GAGATCGAAT CAGGCGTTTC TTTCCCAAAG GGGACCTTGA GβTCCTGCAG 900
GCCCAGGTGG AGAGGATTAT GACCCGGAAG GAGCTCCTβA CAGTCTATTC TTCTGAGGAT 960
GβGTCTGAGG AATTCGAGAC CATAGTTTTβ AAββCCCTTG TGAAGGCCTβ TGGGAGCTCG 1020
GAGGCCTCAG CCTACCTGGA TGAβCTGCGT TTβGCTGTββ CTTGGAACCG CGTGGACATT 1080
GCCCAGAGTG AACTCTTTCG GGGGGACATC CAATGGCGGT CCTTCCATCT CGAAGCTTCC 1140
CTCATGGACG CCCTGCTGAA TGACCGGCCT GAβTTCGTGC GCTTGCTCAT TTCCCACGGC 1200
CTCAGCCTGG GCCACTTCCT GACCCCGATG CβCCTGGCCC AACTCTACAG CβCGGCGCCC 1260
TCCAACTCGC TCATCCGCAA CCTTTTGβAC CAGGCGTCCC ACAβCβCAβG CACCAAAGCC 1320
CCAGCCCTAA AAβββGGAGC TβCββAGCTC CGGCCCCCTG ACβTββββCA TGTGCTGAGG 1380
ATGCTGCTββ βGAAGATGTG CGCGCCβAββ TACCCCTCCG GGGβCβCCTG GβACCCTCAC 1440
CCAββCCAGG GCTTCGGGGA GAβCATβTAT CTGCTCTCGG ACAAGGCCAC CTCGCCGCTC 1500
TCβCTββATG CTGGCCTCGG GCAG CCCCC TGGAGCGACC TGCTTCTTTG ββCACTβTTG 1560
CTGAACAGββ CACAGATCGC CATGTACTTC TGGGAGATGG GTTCCAATβC AβTTTCCTCA 1620
GCTCTTGββG CCTGTTTGCT GCTCCGGGTG ATββCACβCC TGGAGCCTGA CGCTGAβGAG 1680
GCAGCACGGA βGAAAGACCT GGCβTTCAAβ TTTβAββββA TGGGCGTTGA CCTCTTTGGC 1740
GAGTGCTATC GCAGCAGTGA GβTGAβGGCT GCCCGCCTCC TCCTCCGTCβ CTβCCCGCTC 1800
TGGGGGGATG CCACTTGCCT CCAGCTGGCC ATGCAAGCTG ACGCCCGTGC CTTCTTTGCC 1860
CAGGATGGGG TACAGTCTCT GCTβACACAβ AAGTCGTGGG GAGATATGGC CAGCACTACA 1920
CCCATCTββG CCCTGGTTCT CGCCTTCTTT TGCCCTCCAC TCATCTACAC CCGCCTCATC 1980
ACCTTCAββA AATCAGAAGA GGAGCCCACA CGGGAGGAGC TAGAGTTTGA CATGGATAGT 2040
GTCATTAATG GGGAAGGGCC TGTCGGGACG GCGGACCCAG CCGAGAAGAC βCCβCTβββG 2100
GTCCCGCGCC AGTCGGGCCG TCCGGGTTGC TGCββGββCC GCTGCGGGGG GCβCCGGTGC 2160
CTACGCCGCT GGTTCCACTT CTGGGGCGCG CCGβTβACCA TCTTCATGGβ CAACβTβGTC 2220
AGCTACCTGC TGTTCCTGCT GCTTTTCTCG CβGGTGCTGC TCGTGGATTT CCAGCCGGCG 2280
CCGCCCβGCT CCCTGGAGCT βCTGCTCTAT TTCTGGGCTT TCACGCTGCT GTGCGAGGAA 2340
CTGCGCCAGG GCCTGAGCGβ AββCβGGGGC AGCCTCGCCA GCGβGGGCCC CGGGCCTGGC 2400
CATGCCTCAC TGAGCCAGCG CCTGCGCCTC TACCTCGCCG ACAβCTGGAA CCAGTGCGAC 2460
CTAGTGβCTC TCACCTGCTT CCTCCTGGGC GTGGGCTGCC ββCTGACCCC GGGTTTGTAC 2520
CACCTGGβCC βCACTGTCCT CTGCATCGAC TTCATGβTTT TCACGGTGCG GCTGCTTCAC 2580
ATCTTCACGG TCAACAAACA GCTGGGGCCC AAGATCGTCA TCGTβAGCAA GATGATGAAG 2640
GACGTGTTCT TCTTCCTCTT CTTCCTCGGC GTGTGGCTGβ TAβCCTATGG CGTGGCCACG 2700
GAGβGGCTCC TGAGGCCACG GGACAGTGAC TTCCCAAGTA TCCTGCGCCG CGTCTTCTAC 2760
CβTCCCTACC TGCAGATCTT CGGGCAGATT CCCCAGGAGG ACATGGACGT GGCCCTCATG 2820
GAβCACAβCA ACTGCTCGTC GGAGCCCGGC TTCTGGGCAC ACCCTCCTGG GGCCCAGGCG 2880
GGCACCTGCG TCTCCCAGTA TGCCAACTGG CTGGTGGTGC TGCTCCTCGT CATCTTCCTG 2940
CTCβTββCCA ACATCCTGCT GGTCAACTTG CTCATTGCCA TGTTCAGTTA CACATTCGGC 3000
AAAGTACAGG GCAACAGCGA TCTCTACTGG AAGGCGCAGC GTTACCGCCT CATCCGGGAA 3060
TTCCACTCTC GGCCCGCGCT GGCCCCGCCC TTTATCGTCA TCTCCCACTT GCGCCTCCTG 3120
CTCAGGCAAT TGTGCAGGCG ACCCCGGAGC CCCCAGCCβT CCTCCCCGGC CCTCGAGCAT 3180
TTCCGGGTTT ACCTTTCTAA GGAAGCCGAG CGGAAGCTGC TAACβTGGGA ATCGGTGCAT 3240
AAβGAGAACT TTCTGCTGGC ACGCβCTAGG GACAAβCβGG AGAGCGACTC CGAGCβTCTG 3300
AAGCGCACGT CCCAGAAGGT GβACTTGGCA CTGAAACAβC TGGGACACAT CCGCGAGTAC 3360
GAACAGCGCC TGAAAGTGCT GβAGCGGβAG GTCCAGCAGT GTAGCCGCGT CCTGGGGTββ 3420
GTGGCCGAGG CCCTGAGCCG CTCTCCCTTG CTGCCCCCAG GTGGGCCGCC ACCCCCTGAC 3480 CTβCCTGGβT CCAAAGACTG A
A198 Prote sequence: Gene name : ESTs Unigene number: Hs.31608 Probeset Accession ft: H18836 Protein Accession ft: none found Signal sequence: none found
Transmembrane domains: 214-230, 537-556, 642-662, 730-752, 760-782, 815-837, 842-864, 877-899, 973-995
Cellular Localization: plasma membrane
1 11 21 31 41 51
I I I I I I
MEDAFGAAW TVWDSDAHTT EKPTDAYGEL DFTGAGRKHS NFLRLSDRTD PAAVYSLVTR 60
TWGFRAPNLV VSVLGGSGGP VLQTWLQDLL RRGLVRAAQS TGAWIVTGGL HTGIβRHVβV 120 AVRDHQMAST GGTKWAMβV APWGWRNRD TLINPKGSFP ARYRWRGDPE DGVQFPLDYN 180
YSAFFLVDDβ THGCLGGENR FRLRLESYIS QQKTGVGGTG IDIPVLLLLI DGDEKMLTRI 240
ENATQAQLPC LLVAGSβGAA DCLAETLEDT LAPGSGGARQ GEARDRIRRF FPKGDLEVLQ 300
AQVERIMTRK ELLTVYSSED GSEEFETIVL KALVKACβSS EASAYLDELR LAVAWNRVDI 360
AQSELFRβDI QWRSFHLEAS LMDALLNDRP EFVRLLISHG LSLGHFLTPM RLAQLYSAAP 420 SNSLIRNLLD QASHSAGTKA PALKGGAAEL RPPDVGHVLR MLLGKMCAPR YPSGβAWDPH 480
PGQGFGESMY LLSDKATSPL SLDAGLGQAP WSDLLLWALL LNRAQMAMYF WEMGSNAVSS 540
ALGACLLLRV MARLEPDAEE AARRKDLAFK FEGMβVDLFG ECYRSSEVRA ARLLLRRCPL 600
WGDATCLQLA MQADARAFFA QDβVQSLLTQ KWWGDMASTT PIWALVLAFF CPPLIYTRLI 660
TFRKSEEEPT REELEFDMDS VINGEβPVGT ADPAEKTPLG VPRQSGRPGC CGGRCGGRRC 720 LRRWFHFWGA PVTIFMβNW SYLLFLLLFS RVLLVDFQPA PPβSLELLLY FWAFTLLCEE 780
LRQβLSβGGG SLASββPGPG HASLSQRLRL YLADSWNQCD LVALTCFLLG VGCRLTPGLY 840
HLGRTVLCID FMVFTVRLLH IFTVNKQLGP KIVIVSKMMK DVFFFLFFLG VWLVAYGVAT 900
EGLLRPRDSD FPSILRRVFY RPYLQIFGQI PQEDMDVALM EHSNCSSEPG FWAHPPGAQA 960 βTCVSQYANW LWLLLVIFL LVANILLVNL LIAMFSYTFG KVQGNSDLYW KAQRYRLIRE 1020 FHSRPALAPP FIVISHLRLL LRQLCRRPRS PQPSSPALEH FRVYLSKEAE RKLLTWESVH 1080
KENFLLARAR DKRESDSERL KRTSQKVDLA LKQLGHIREY EQRLKVLERE VQQCSRVLGW 1140
VAEALSRSAL LPPGGPPPPD LPGSKD
A199 DNA SEQUENCE
Gene name: ESTs
Unigene number: Hs.40808
Probeset Acceεεion ft: AA054237
Nucleic Acid Acceεεion ft: AA054237
Coding sequence: 1-894 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
ATGGAGCCβC GGβCGCTCGT CACGβCGCTC AGCCTCGGCC TCAGCCTGTG CTCCCTGββG 60
CTGCTCGTCA CGGCCATCTT CACCGACCAC TGGTACGAβA CCβACCCCCG GCGCCACAAG 120
GAβAβCTβCG AGCGCAGCCG CGCGGGCGCC GACCCCCCGβ ACCAGAAGAA CCGCCTGATG 180
CCGCTGTCGC ACCTGCCGCT βCGGGACTCG CCCCCGCTGG GGCGCCGGCT GCTCCCGGGC 240
GGCCCGGGGC GCGCCGACCC CGAGTCCTGG CGCTCβCTCC TGGGGCTCGG CGββCTβGAC 300
GCCGAGTGCG GCCGGCCCCT CTTCGCCACC TACTCGGGCC TCTGGAGGAA GTGCTACTTC 360
CTGGGCATCG ACCGβGACAT CβACACCCTC ATCCTβAAAG GTATTGCGCA GCGATβCACG 420
GCCATCAAGT ACCACTTTTC TCAGCCCATC CGCTTβCβAA ACATTCCTTT TAATTTAACC 480
AAGACCATAC AGCAAGATGA βTGGCACCTG CTTCATTTAA GAAGAATCAC TGCTGβCTTC 540
CTCGGCATGG CCGTAGCCGT CCTTCTCTGC GGCTGCATTG TGGCCACAGT CAβTTTCTTC 600
TGGGAGGAGA GCTTGACCCA GCACGTGGCT GGACTCCTGT TCCTCATGAC AGβGATATTT 660
TGCACCATTT CCCTCTGTAC TTATGCCGCC AGTATCTCGT ATGATTTGAA CCGGCTCCCA 720
AAGCTAATTT ATAGCCTGCC TGCTGATGTG βAACATGGTT ACAGCTββTC CATCTTTTGC 780
GCCTGGTGCA GTTTAGGCTT TATTGTGGCA GCTGGAGGTC TCTGCATCGC TTATCCGTTT 840 ATTAGCCGGA CCAAGATTGC ACAGCTAAAG TCTGGCAGAG ACTCCACGGT ATGA A200 Protein sequence: Gene name: ESTs Unigene number: Hs.40808 Probeset Accession #: AA054237 Protein Accesεion #: none found Signal εequence: 1-18 Transmembrane domains: 179-201, 209-231, 257-279 Cellular Localization: plasma membrane
21 31
MEPRALVTAL SLGLSLCSLG LLVTAIFTDH WYETDPRRHK ESCERSRAGA DPPDQKNRLM 60
PLSHLPLRDS PPLGRRLLPG GPGRADPESW RSLLGLGGLD AECGRPLFAT YSβLWRKCYF 120
LGIDRDIDTL ILKGIAQRCT AIKYHFSQPI RLRNIPFNLT KTIQQDEWHL LHLRRITAGF 180
LGMAVAVLLC GCIVATVSFF WEESLTQHVA GLLFLMTGIF CTISLCTYAA SISYDLNRLP 240 KLIYSLPADV EHβYSWSIFC AWCSLGFIVA AGβLCIAYPF ISRTKIAQLK SβRDSTV
A201 DNA SEQUENCE
Gene name : CDA14
Unigene number : Hs .26813
Probeset Accesεion # : N32912
Nucleic Acid Acceεεion ft : NM_016570
Coding sequence : 1- 1134 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51
I I I I I I
ATGAββCGAC TGAATCββAA AAAAACTTTA AGTTTGGTAA AAGAGTTGGA TGCCTTTCCG 60 AAGGTTCCTG AGAGCTATGT AGAβACTTCA GCCAGTGGAG βTACAGTTTC TCTAATACCA 120 TTTACAACTA TGGCTTTATT AACCATAATG GAATTCTCAG TATATCAAGA TACATGGATG 180 AAGTATGAAT ACGAAGTAGA CAAGGATTTT TCTAGCAAAT TAAGAATTAA TATAGATATT 240 ACTGTTGCCA TβAAβTGTCA ATATGTT6GA GCβGATGTAT TGGATTTAGC AGAAACAATG 300 GTTGCATCTβ CAGATGGTTT AGTTTATGAA CCAACAGTAT TTGATCTTTC ACCACAGCAG 360 AAAβAβTββC AGAGβATGCT GCAGCTGATT CAGAGTAGGC TACAAGAAGA GCATTCACTT 420 CAACATβTGA TATTTAAAAG TGCTTTTAAA AGTACATCAA CAGCTCTTCC ACCAAGAGAA 480 GATGATTCAT CACAGTCTCC AAATGCATGC AGAATTCATG GCCATCTATA TGTCAATAAA 540 GTAGCAGGGA ATTTTCACAT AACAGTGGGC AAGGCAATTC CACATCCTCG TGGTCATGCA 600 CATTTββCAβ CACTTGTCAA CCATGAATCT TACAATTTTT CTCATAGAAT AGATCATTTG 660 TCTTTTββAβ AGCTTGTTCC AGCAATTATT AATCCTTTAG ATGGAACTGA AAAAATTGCT 720 ATAβATCACA ACCAβATGTT CCAATATTTT ATTACAGTTG TGCCAACAAA ACTACATACA 780 TATAAAATAT CAGCAGACAC CCATCAβTTT TCTGTGACAG AAAGGGAACβ TATCATTAAC 840 CATGCTβCAG GCAGCCATGG AGTCTCTGGβ ATATTTATβA AATATGATCT CAGTTCTCTT 900 ATGGTGACAG TTACTGAGGA GCACATGCCA TTCTGGCAGT TTTTTGTAAG ACTCTGTGβT 960 ATTGTTGGAG GAATCTTTTC AACAACAββC ATGTTACATG GAATTGGAAA ATTTATAβTT 1020 GAAATAATTT GCTGTCGTTT CAGACTTβGA TCCTATAAAC CTGTCAATTC TGTTCCTTTT 1080 GAGGATGGCC ACACAGACAA CCACTTACCT CTTTTAGAAA ATAATACACA TTGA
A202 Protein sequence : Gene name : CDA14 Unigene number : HS .26813 Probeset Accession ft : N32912 Protein Accession ft : NP_057654 Signal sequence : none found
Transmembrane domains : none found Cellular Localization: nuclear
MRRLNRKKTL SLVKELDAFP KVPESYVETS ASβGTVSLIA FTTMALLTIM EFSVYQDTWM 60
KYEYEVDKDF SSKLRINIDI TVAMKCQYVG ADVLDLAETM VASADGLVYE PTVFDLSPQQ 120
KEWQRMLQLI QSRLQEEHSL QDVIFKSAFK STSTALPPRE DDSSQSPNAC RIHCHLYVNK 180
VAGNFHITVG KAIPHPRGHA HLAALVNHES YNFSHRIDHL SFGELVPAII NPLDGTEKIA 240
IDHNQMFQYF ITWPTKLHT YKISADTHQF SVTERERIIN HAAGSHGVSβ IFMKYDLSSL 300
MVTVTEEHMP FWQFFVRLCG IVGGIFSTTG MLHGIGKFIV EIICCRFRLG SYKPVNSVPF 360
EDGHTDNHLP LLENNTH
A203 DNA SEQUENCE
Gene name: dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
Unigene number: Hs.44926
Probeset Accession ft: S79876
Nucleic Acid Accession ft : NM_001935.1
Coding sequence: 76-2301 (underlined sequences correspond to start and stop codons)
11 21 31 41 51
I I I I
CGCGCGTCTC CGCCGCCCGC βTβACTTCTG CCTGCGCTCC TTCTCTGAAC GCTCACTTCC 60 GAGGAGACGC CGACGATGAA βACACCβTGG AAGATTCTTC TGGGACTGCT GGGTβCTGCT 120 GCGCTTGTCA CCATCATCAC CGTGCCCGTG GTTCTGCTGA ACAAAGGCAC AGATGATGCT 180 ACAGCTGACA GTCGCAAAAC TTACACTCTA ACTGATTACT TAAAAAATAC TTATAGACTG 240 AAGTTATACT CCTTAAGATG GATTTCAGAT CATGAATATC TCTACAAACA AGAAAATAAT 300 ATCTTG TAT TCAATGCTGA ATATGGAAAC AGCTCAGTTT TCTTGGAGAA CAβTACATTT 360 GATGAGTTTG GACATTCTAT CAATGATTAT TCAATATCTC CTGATGGGCA GTTTATTCTC 420 TTAGAATACA ACTACGTβAA GCAATGGAGG CATTCCTACA CAGCTTCATA TGACATTTAT 480 GATTTAAATA AAAGGCAGCT GATTACAGAA GAGAGGATTC CAAACAACAC ACAGTGGGTC 540 ACATGGTCAC CAGTGGGTCA TAAATTGGCA TATGTTTGGA ACAATGACAT TTATGTTAAA 600 ATTGAACCAA ATTTACCAAG TTACAGAATC ACATGGACGG GGAAAGAAGA TATAATATAT 660 AATGGAATAA CTGACTGGGT TTATGAAGAG GAAGTCTTCA GTGCCTACTC TGCTCTGTGG 720 TββTCTCCAA ACGGCACTTT TTTAGCATAT GCCCAATTTA ACGACACAGA AGTCCCACTT 780 ATTGAATACT CCTTCTACTC TGATGAGTCA CTGCAGTACC CAAAGACTGT ACGGGTTCCA 840 TATCCAAAGG CAββAGCTβT GAATCCAACT GTAAAGTTCT TTGTTGTAAA TACAGACTCT 900 CTCAGCTCAG TCACCAATGC AACTTCCATA CAAATCACTG CTCCTGCTTC TATGTTGATA 960 GGGGATCACT ACTTGTGTGA TGTGACATGβ GCAACACAAG AAAGAATTTC TTTGCAGTGG 1020 CTCAGGAGGA TTCAGAACTA TTCGGTCATG GATATTTGTG ACTATGATGA ATCCAGTGGA 1080 AGATGGAACT GCTTAGTGGC ACGGCAACAC ATTGAAATGA GTACTACTGG CTGGGTTGGA 1140 AGATTTAGβC CTTCAGAACC TCATTTTACC CTTGATββTA ATAGCTTCTA CAAGATCATC 1200 AGCAATGAAβ AAGβTTACAG ACACATTTGC TATTTCCAAA TAGATAAAAA AβACTGCACA 1260 TTTATTACAA AAGGCACCTG GGAAGTCATC GGGATAGAAG CTCTAACCAG TGATTATCTA 1320 TACTACATTA GTAATGAATA TAAAGGAATG CCAGGAGGAA GGAATCTTTA TAAAATCCAA 1380 CTTATTGACT ATACAAAAβT GACATGCCTC AGTTβTGAGC TGAATCCβGA AAGGTGTCAG 1440 TACTATTCTG TGTCATTCAG TAAAGAGβCG AAGTATTATC AGCTβAGATG TTCCGGTCCT 1500 GGTCTGCCCC TCTATACTCT ACACAGCAGC GTβAATβATA AAGGGCTβAG AGTCCTGGAA 1560 GACAATTCAG CTTTGGATAA AATGCTGCAG AATGTCCAGA TGCCCTCCAA AAAACTGGAC 1620 TTCATTATTT TGAATGAAAC AAAATTTTββ TATCAGATGA TCTTGCCTCC TCATTTTGAT 1680 AAATCCAAGA AATATCCTCT ACTATTAGAT GTGTATGCAG GCCCATGTAβ TCAAAAAGCA 1740 GACACTGTCT TCAβACTβAA CTGβGCCACT TACCTTGCAA GCACAGAAAA CATTATAGTA 1800 GCTAGCTTTG ATGGCAGAGG AAGTGGTTAC CAAGGAGATA AGATCATGCA TβCAATCAAC 1860 AGAAβACTGG βAACATTTβA AGTTβAAGAT CAAATTGAAG CAGCCAGACA ATTTTCAAAA 1920 ATGGGATTTG TGCACAACAA ACGAATTβCA ATTTGGGGCT GGTCATATGG AβββTACGTA 1980 ACCTCAATββ TCCTGGGATC GGGAAGTGGC GTGTTCAAGT GTGGAATAGC CGTGGCGCCT 2040 GTATCCCGGT GββAGTACTA TGACTCAGTG TACACAGAAC GTTACATβGG TCTCCCAACT 2100
CCAGAAGACA ACCTTGACCA TTACAGAAAT TCAACAGTCA TGAGCAβAGC TGAAAATTTT 2160
AAACAAGTTβ AβTACCTCCT TATTCATβGA ACAGCAGATG ATAACGTTCA CTTTCAGCAG 2220
TCAGCTCAGA TCTCCAAAGC CCTGGTCGAT GTTGGAGTGβ ATTTCCAGGC AATGTGGTAT 2280
ACTGATGAAG ACCATGGAAT AGCTAβCAGC ACAGCAGACC AACATATATA TACCCACATG 2340
AGCCACTTCA TAAAACAATG TTTCTCTTTA CCTTAGCACC TCAAAATACC ATGCCATTTA 2400
AAGCTTATTA AAACTCATTT TTGTTTTCAT TATCTCAAAA CTGCACTGTC AAGATGATGA 2460
TGATCTTTAA AATACACACT CAAATCAAGA AACTTAAGβT TACCTTTGTT CCCAAATTTC 2520
ATACCTATCA TCTTAAGTAG GGACTTCTGT CTTCACAACA GATTATTACC TTACAGAAGT 2580
10 TTGAATTATC CGGTCβGGTT TTATTGTTTA AAATCATTTC TGCATCAGCT GCTGAAACAA 2640
CAAATAGβAA TTGTTTTTAT GGAGGCTTTG CATAGATTCC CTGAGCAGβA TTTTAATCTT 2700
TTTCTAACTG GACTGGTTCA AATGTTGTTC TCTTCTTTAA AGGGATGGCA AGATGTGGGC 2760
AGTGATGTCA CTAGGGCAGG GACAGGATAA GAGGGATTAG GGAGAGAAβA TAGCAGGGCA 2820
TGGCTGGGAA CCCAAGTCCA AGCATACCAA CACGAGCAGG CTACTGTCAG CTCCCCTCGG 2880
15 AGAAGAGCTG TTCACCACGA GACTGGCACA GTTTTCTGAG AAAGACTATT CAAACAGTCT 2940
CAGGAAATCA AATATCGAAA GCACTGACTT CTAAGTAAAC CACAGCAGTT GAAAGACTCC 3000
AAAGAAATGT AAGGGAAACT GCCAGCAACG CAGCCCCCAG GTGCCAGTTA TGGCTATAGG 3060
TGCTACAAAA ACACAGCAAG GβTGATGGGA AAGCATTGTA AATGTβCTTT TAAAAAAAAA 3120
TACTGATGTT CCTAGTGAAA GAGGCAGCTT GAAACTGAGA TGTGAACACA TCAGCTTCCC 3180
20 CTGTTAAAAG ATGAAAATAT TTGTATCACA AATCTTAACT TβAAGGAGTC CTTGCATCAA 3240
TTTTTCTTAT TTCATTTCTT TβAGTGTCTT AATTAAAAGA ATATTTTAAC TTCCTTGGAC 3300
TCATTTTAAA AAATGGAACA TAAAATACAA TGTTATGTAT TATTATTCCC ATTCTACATA 3360 CTATGβAATT TCTCCCAβTC ATTTAATAAA TGTGCCTTCA TTTTTTC
25
A204 Protein sequence: Gene name: dipeptidylpeptidaεe IV (CD26, adenosine deaminase complexing protein 2) Unigene number: Hε.44926 Probeset Accession #: S79876
_>U Protein Accession ft: NP_001926.1 Signal sequence: none found Transmembrane domains : 6-28 DPPIv_N_term domain: 43-557 Peptidase_S9 domain: 558-635
35 Cellular Localization: plasma membrane
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40 MKTPWKILLG LLGAAALVTI ITVPWLLNK GTDDATADSR KTYTLTDYLK NTYRLKLYSL 60
RWISDHEYLY KQENNILVFN AEYGNSSVFL ENSTFDEFGH SINDYSISPD GQFILLEYNY 120
VKQWRHSYTA SYDIYDLNKR QLITEERIPN NTQWVTWSPV GHKLAYVWNN DIYVKIEPNL 180
PSYRITWTGK EDIIYNGITD WVYEEEVFSA YSALWWSPNG TFLAYAQFND TEVPLIEYSF 240
YSDESLQYPK TVRVPYPKAG AVNPTVKFFV VNTDSLSSVT NATSIQITAP ASMLIGDHYL 300
45 CDVTWATQER ISLQWLRRIQ NYSVMDICDY DESSGRWNCL VARQHIEMST TGWVGRFRPS 360
EPHFTLDβNS FYKIISNEEG YRHICYFQID KKDCTFITKG TWEVIGIEAL TSDYLYYISN 420
EYKGMPGGRN LYKIQLIDYT KVTCLSCELN PERCQYYSVS FSKEAKYYQL RCSGPGLPLY 480
TLHSSVNDKG LRVLEDNSAL DKMLQNVQMP SKKLDFIILN ETKFWYQMIL PPHFDKSKKY 540
PLLLDVYAGP CSQKADTVFR LNWATYLAST ENIIVASFDG RGSβYQβDKI MHAINRRLβT 600
50 FEVEDQIEAA RQFSKMGFVD NKRIAIWGWS YGGYVTSMVL GSGSβVFKCG IAVAPVSRWE 660
YYDSVYTERY MGLPTPEDNL DHYRNSTVMS RAENFKQVEY LLIHGTADDN VHFQQSAQIS 720 KALVDVGVDF QAMWYTDEDH GIASSTAHQH IYTHMSHFIK QCFSLP
A205 DNA SEQUENCE
55 Gene name: predicted exon Unigene number: none found Probeset Accession # : none found Nucleic Acid Accession #: none found Coding sequence: 1-261 (underlined sequences correspond to start and stop codons)
60
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ATGGCTCTGG CGAAGGTGAG GGAGCCAAAC GCAAATGACA ATGCCATCAG AGTTGACAAC 60
65 AGAAGTGTGA TTAAAGTGCG TGCTAACCAβ TGTTCCCTGC ATGAGGCAGA AAGTGAATCC 120
AβAAACCCTC AGβAβCTCTG βATGGGCCTG CTCCTCTTGA TGβββGTCCT AGAAGCATGT 180 βTββAAATGA GβCCTCTGTC AβTCTGGTCC CTGAGAGATG ACAAGGAGCA GAGCCCCCAC 240 CAβCCCACAC TGGATGTCTA A
70
A206 Protein sequence:
Gene name: predicted exon
Unigene number: none found
Probeset Accession # : none found
75 Protein Accession ft: none found
Signal sequence: none found
Tranεmembrane domains: 46-68
Cellular Localization: not determined
80
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MALAKVREPN ANDNAIRVDN RSVIKVRANQ CSLHpAESES RNPQELWMGL LLLMGVLEAC VEMRPLSVWS LRDDKEQSPH QPTLDV A207 DNA SEQUENCE βene name: ESTs Unigene number: HS.222886 Probeεet Accession # : AI672225 Nucleic Acid Accession ft: none found Coding εequence : 1-462 (underlined sequences correspond to start and stop codons)
11 21 31
ATGCCAAATG CTGAGTTAGA AGCAAAGAGC CTTGβAAGCA GTAAATGTTT AAAAACTGCT 60
CTCATACTTG CTGTATGTTG TGGATCAGCA AATATAGTCA GCCCTCTACT TGAGCAAAAT 120
ATTGATGTAT CTTCTCAAGA TCTGGACAGA CGβCCAGAGA GTATGCTGTT TCTAβTCATC 180
ATCATGTGGA CCAGTTTTGT GGAAGACAAT CTTTCCATGG GCTGGGGGAA GCTAGAAβAT 240
TTTATGGCTA TTGAAGAAGA AATGAAGAAG CACGGAAGTA CTCATGTGGG ATTCCCAβAA 300
AACCTGACTA ATGGTGCCβC TGCTGGCAAT GGTβATGATG GATTAATTCC TCCAAGGAAβ 360
ACCAβAACAC CTβAAAβCCA GCAATTTCCT βACACTGAGA ATGAAGAGTA TCACAGGTTT 420
GTCAAAGATC AGATAGTTGT AGATATβCGG CGTTATTTCT_ GA
A208 Protein sequence:
Gene name: EStS
Unigene number: HS.222886
Probeset Accession ft: AI672225
Protein Accession ft: none found
Signal sequence: none 3 Eound
Transmembrane domains : 16-38
Cellular Localization: not determined
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MPNAELEAKS LGSSKCLKTA LILAVCCGSA NIVSPLLEQN IDVSSQDLDR RPESMLFLVI 60 IMWTSFVEDN LSMGWGKLED FMAIEEEMKK HβSTHVGFPE NLTNGAAAGN βDDGLIPPRK 120 SRTPESQQFP DTENEEYHRF VKDQIWDMR RYF
A209 DNA SEQUENCE
Gene name: odz (odd Oz/ten-m, Drosophila) homolog 1
Unigene number: Hs.23796 Probeset Accession ft: NM_014253
Nucleic Acid Accession #: NM_014253
Coding sequence: 65-8242 (underlined sequences correspond to start and stop codons)
1 11 21 31 41 51 1 1 I 1 1 1 | 1 | 1 | 1 GACTGCTTGC ATTAAAGGAC TTCCTCATCC TTTTTTTCAT GAAACTGAGC TTGCTTAATC 60
AGAGATGGAG CAAACTGACT GCAAACCCTA CCAGCCTCTA CCAAAAGTCA AGCATGAAAT 120
GGATCTAGCT TACACCAGTT CTTCTGATGA GAGTGAAGAT GGAAGAAAAC CAAGACAGTC 180
ATACAACTCC AG6GAGACCC TGCACGAGTA TAACCAGGAβ CTGAGGATGA ATTACAATAG 240
CCAGAGTAGA AAGAββAAAG AAGTAGAAAA ATCTACTCAA GAGATGGAAT TCTGTβAAAC 300
CTCTCACACT CTβTβCTCTG GCTACCAAAC AGACATGCAC AGCGTTTCTC GGCATGβCTA 360
CCAGCTAGAG ATGGGATCTG ATGTGGACAC AβAβACAGAA GGTGCTGCCT CACCTGACCA 420
TGCACTAAGA ATGTGGATAA GGGGAATGAA ATCAGAGCAT AGTTCCTGTT TGTCCAGCCβ 480 ββCCAACTCT βCATTATCCT TGACTGACAC TGACCATGAA AGGAAGTCTG ATββββAAAA 540
TββTTTCAAA TTCTCTCCTβ TTTGTTGTGA CATGGAGGCT CAAGCTGGGT CTACTCAAGA 600
TGTGCAβAβC AβCCCACACA ACCAGTTCAC CTTCAβACCC CTCCCACCGC CACCTCCGCC 660
TCCTCATGCC TGCACCTGTG CCAGGAAGCC ACCCCCTGCA GCGGACTCTC TTCAGAGGAG 720
ATCAATGACT ACCCGCAGCC AGCCCAGCCC AGCTGCTCCA GCTCCCCCAA CCAGCACGCA 780
GGATTCAGTC CATCTGCATA ACAGCTGGGT CCTGAACAGC AACATACCAT TGGAGACCAG 840
GCATTCCCTG TTCAAACATβ GATCTGGTTC CTCTGCGATC TTCAGTGCAG CCAGTCAβAA 900
CTACCCTCTG ACATCCAATA CCGTGTACTC GCCCCCTCCC AGGCCTCTTC CTCβAAβCAC 960
CTTTTCCCGA CCTGCCTTTA CCTTTAACAA ACCTTACAGG TGCTGCAACT GGAAGTGCAC 1020
AGCATTGAGC GCCACTGCAA TCACAGTGAC TTTGGCCTTβ TTACTAGCCT ATGTGATTGC 1080
AGTGCATTTG TTCGGCCTGA CTTGGCAGTT GCAACCAGTT GAAGGAGAGC TGTATGCAAA 1140
TGGAGTTAGC AAAGGGAACA GGGGGACCGA GTCCATGGAC ACTACTTACT CTCCAATTGG 1200
AGGAAAAGTT TCTGATAAAT CAGAGAAAAA AGTGTTTCAG AAGGGACGGG CGATAGACAC 1260
TGGAGAAGTT GACATTGGTβ CACAGGTCAT GCAGACCATT CCACCTGGTT TATTCTGGCG 1320
TTTCCAGATT ACTATCCACC ATCCAATATA TCTGAAGTTC AATATTTCTT TAGCCAAGGA 1380
CTCTCTGCTG GGAATTTATG GCAGAAGAAA CATTCCACCT ACACATACTC AGTTTGATTT 1440
TGTAAAACTA ATGGATGGCA AACAGCTGGT CAAGCAGGAC TCCAAGGGCT CTGATGATAC 1500
ACAGCACTCC CCTCGGAACC TGATCTTAAC TTCGCTTCAG GAGACAGGTT TCATAGAβTA 1560
TATGGATCAA GGACCTTGGT ATCTGβCGTT TTACAATGAT GGAAAAAAβA TGGAGCAAGT 1620
ATTCGTGTTA ACTACAGCAA TTGAAATAAT GGATGACTβT TCAACCAATT GCAATββAAA 1680
TGGAβAβTβT ATCTCTGGCC ATTGTCATTβ TTTCCCAGGA TTCCTTGGAC CTGACTGTGC 1740
TAGAGATTCC TGCCCTGTGC TGTGTGGTGG GAATGGAGAA TACGAβAAAG GACACTGTGT 1800
CTGCCGGCAT GGCTGGAAGG GGCCAGAGTG TGACGTTCCG GAAGAACAAT GCATTGATCC 1860
AACATGCTTT GGCCACGGCA CCTβCATCAT GGGAGTCTGC ATCTGTGTGC CAGGATACAA 1920
AGβAβAAATA TGCGAGGAAG AGGACTGCCT AGACCCAATG TGTTCCAACC ATGGCATCTG 1980
TGTAAAAGGA GAATGTCACT GTTCTACTGG CTβGGGAGGA GTTAACTβTG AAACACCACT 2040
TCCTGTATGT CAAGAGCAGT GCTCAGGACA CGGAACTTTT CTTCTGGACG CTGGAβTATG 2100
CAGCTGTGAT CCCAAGTGGA CAGGATCTGA CTGCTCAACA GAGCTGTGTA CCATGβAβTG 2160
TGGTAGCCAT GGAβTCTβCT CAAGAGGAAT TTGCCAGTGT GAAβAAGGCT GGGTAGGACC 2220
AACATGTGAG GAACGCTCCT GTCATTCTCA TTGTACTGAG CATGGCCAAT GCAAAGATGG 2280 AAAATGTGAG TGTAGCCCTβ GATβββAGGβ CGACCACTβC ACAATTβCTC ACTACTTAGA 2340 TGCTβTCCGA GATGGCTGCC CAGβGCTCTβ CTTTCβAAAT GGACβATGTA CCCTGGATCA 2400 AAATGβTTββ CACTGTGTβT βTCACGTGGG TTGGAGTGGG ACAGGCTGCA ATGTTGTCAT 2460 GGAAATGCTT TGTGGAGATA ACTTGGACAA TGATGGAGAT GGTTTAACCG ACTGTGTGGA 2520 TCCTGACTGT TβTCAACAAA CCAACTβTTA TATAAGTCCT CTCTGCCAGG GCTCACCAGA 2580 TCCTCTTGAC CTCATTCAGC AAAGCCAAAC TCTCTTCTCT CAGCACACTT CAAβACTTTT 2640 TTATGATCGA ATCAAATTCC TCATTGGCAA GGACAGTACT CATGTCATTC CTCCTGAGGT 2700 GTCATTTGAC AGCAGGCGTG CCTGTGTGAT TCGAGGCCAA GTGGTGGCCA TAGATGGAAC 2760 TCCTCTAGTβ ββAGTGAATG TCAGTTTCTT GCACCACAGT βATTATGGGT TTACCATCAG 2820 CCGGCAAGAT GGAAGCTTTG ACCTCGTGGC CATCGGTGGC ATCTCTGTCA TCTTAATCTT 2880 CGACCGATCC CCTTTCCTGC CTGAGAAGAG AACACTCTGG TTGCCTTGGA ATCAGTTTAT 2940 TGTββTAGAG AAAGTCACCA TGCAGAGAGT TGTATCAGAC CCGCCATCCT GCGATATCTC 3000 CAACTTTATC AGCCCAAACC CTATTGTGCT TCCTTCACCG CTCACATCAT TTGGAGGGTC 3060 CTGTCCAGAG AGGββAACTA TTGTTCCTGA GCTβCAβGTT GTACAGGAGG AAATTCCCAT 3120 TCCCTCCAGC TTTGTβAGGC TGAGTTACCT GAGCAGCCGC ACCCCTGGGT ATAAAACCCT 3180 GCTACGGATC CTTCTGACAC ATTCAACGAT TCCCβTAGGC ATGATAAAAG TACACCTCAC 3240 AGTAGCTGTG GAAGGGCGAC TCACACAGAA GTGGTTTCCC GCCGCAATTA ATCTTGTCTA 3300 CACATTTGCT TGGAACAAGA CCGATATCTA TGGACAGAAG GTTTGGGGCC TGGCAGAGGC 3360 TTTGGTATCT GTGGβATATG AATATGAAAC GTGCCCTGAC TTTATTCTCT GGGAGCAAAG 3420 GACAGTCGTT TTACAAGGTT TTGAGATGβA TGCTTCTAAC CTAGGAGACT GGTCTTTGAA 3480 TAAGCATCAC ATTTTβAATC CTCAAAβTββ AATCATACAT AAAGGGAATG GAGAAAATAT 3540 GTTCATTTCC CAβCAGCCCC CAGTCATATC AACCATAATG GβTAATGGAC ACCAAAGGAG 3600 TGTAβCCTGC ACCAACTGCA ATGGCCCAGC CCACAACAAC AAACTCTTTG CTCCTGTCGC 3660 CTTAGCTTCT GβCCCTGATβ GCAGTβTβTA TGTTβGCGAC TTCAATTTTG TAAGGAGAAT 3720 ATTTCCCTCG GGAAACTCCG TTAGTATTTT GGAATTAAGC ACAAGTCCTG CTCACAAATA 3780 CTATCTGGCT ATGGACCCTG TGTCTGAATC ACTCTATCTA TCAβACACCA ATACTCβCAA 3840 AGTCTACAAG TTGAAATCTC TTGTGGAGAC GAAAGATCTG TCCAAGAATT TTGAAGTβGT 3900 GGCAGβAACT GGTGATCAGT GCCTTCCCTT TGACCAGAGT CATTGTGGAG ATGGTGGGAG 3960 AGCATCGGAA GCTTCACTβA ATAβCCCTCG AGGCATCACA GTTGATAGGC ATGGATTTAT 4020 TTACTTTGTβ GATGGGACTA TGATTCGCAA AATTGATGAG AATGCTGTGA TCACAACTGT 4080 AATCGGCTCA AATGGTCTGA CTTCCACACA ACCACTβAβC TGTGACTCAβ GAATGβACAT 4140 CACTCAGGTG CGATTAGAGT GGCCAACAβA CCTTGCAGTA AATCCTATGG ACAATTCATT 4200 βTATGTCTTG GATAACAACA TTGTGCTGCA AATTTCTβAG AACAGGCGTG TTCGGATCAT 4260 CGCAβGACGC CCCATTCACT GCCAGGTGCC AGGCATCGAT CATTTCCTGG TCAGCAAGGT 4320 AGCAATTCAC TCCACTCTAG AGTCAGCGAβ GGCCATCAGT GTCTCCCACA GCGGGCTGCT 4380 CTTCATAGCT GAAACAGACG AGAGGAAAGT AAACCGCATT CAβCAAGTAA CCACCAATGG 4440 βGAGATCTAC ATCATCGCTG GTGCCCCCAC TGACTGTGAC TGCAAAATTG ATCCAAACTG 4500 TGACTGTTTT TCAGGTGATG GTGGCTATGC CAAAβATGCA AAGATGAAAG CCCCTTCCTC 4560 CTTAGCAGTG TCGCCTGATG GAACCCTCTA TGTGGCAGAC CTCGGAAATG TTCGAATTCG 4620 TACCATCAβC AGGAACCAAG CCCACCTGAA TGACATGAAC ATTTATGAGA TTGCTTCACC 4680 CGCTGATCAG GAACTGTACC AGTTCACTGT AAATGGAACC CACCTACACA CCCTGAACTT 4740 GATAACAAβG βACTATGTTT ATAACTTCAC CTACAATTCT GAAGβTGACT TGGGCGCGAT 4800 TACCAGCAGC AATGGCAATT CAGTGCACAT TCGCCGTGAT GCAGGCGGAA TGCCGCTATG 4860 GCTTGTGβTG CCTGGCGGAC AAGTATACTG GCTGACTATA AGCAGCAATG GAGTCCTGAA 4920 AAGAGTβTCA GCCCAAGGCT ATAATCCGGC CTTAATGACC TATCCAGGAA ACACAGGGCT 4980 TCTGβCTACC AAAAGTAACG AAAATββATG GACAACCGTT TATGAGTATG ACCCCGAGGG 5040 ACACCTGACC AATGCAACGT TTCCCACTGG AGAGGTCAGC AGCTTCCACA GTGACCTGGA 5100 GAAβCTGACA AAAGTβGAGC TAβATACTTC CAACCGTGAA AATGTCCTCA TGTCAACCAA 5160 CTTGACGGCA ACTAGTACCA TATATATTTT AAAACAAβAA AATACTCAAA GTACCTATCG 5220 GGTGAATCCA GATGGTTCCC TGCGTGTCAC TTTTGCCAGC GGGATGGAGA TCββCCTCAG 5280 CTCAGAGCCC CACATCCTGG CAGGGβCAGT CAACCCTACC CTGGGCAAAT GCAACATCTC 5340 ATTβCCCGGA GAGCACAATG CAAACCTCAT CGAGTGGCGG CAGAGGAAGG AGCAAAACAA 5400 AGGCAATGTT TCGGCTTTTG AAAGβAGGCT GAGGGCCCAC AACAGAAACC TACTCTCCAT 5460 AGATTTTGAT CATATAACCC GCACAGGAAA GATCTATGAT GACCATCGAA AATTCACCCT 5520 TCGAATTCTT TATGACCAGA CTGGβCGACC CATTCTβTGG TCTCCTGTAA GCAGATATAA 5580 TGAAGTGAAC ATCACATATT CACCTTCGGG ATTGGTGACG TTTATTCAAA GAGGAACGTG 5640 GAATGAAAAA ATGGAATATG ACCAGAGTGG GAAAATTATT TCAAGAACTT GGGCTGATGG 5700 GAAAATTTGG AGCTATACCT ACTTAGAAAA ATCTβTGATG CTTCTCCTAC ACAGCCAGCβ 5760 GCGTTACATC TTTGAβTATβ ACCAATCAGA TTGCCTGCTG TCAβTTACCA TβCCTAβCAT 5820 GGTβCGCCAC AGCTTACAAA CCATβCTTTC AβTGGGCTAC TACCGTAATA TCTACACCCC 5880 ACCGGACAβT AGCACTTCTT TTATCCAAGA CTATAGTCGA GATGGCCGAT TGCTACAGAC 5940 CCTGCATCTG GGGACAGβGC GCAGAGTCTT ATACAAGTAC ACCAAGCAAG CAAGGCTTTC 6000 TGAGGTTCTC TATGATACCA CTCAGGTCAC ATTAACATAT GAAGAGTCTT CTGGAGTGAT 6060 TAAGACAATA CACCTGATGC ATβACGGATT CATCTGCACA ATCAGATACA GGCAAACAGG 6120 ACCTCTTATT GβACGCCAβA TTTTCAGATT CAGTGAAGAA GGCCTTCTβA ATGCACGGTT 6180 CGACTACAGC TACAACAATT TCCβAGTCAC AAGCATGCAA GCTGTAATCA ATGAAACCCC 6240 TTTGCCTATA GATCTTTACC GATATGTTβA TGTCTCTGGC AGAACAβAβC AGTTTGGAAA 6300 ATTCAGTGTA ATTAATTACG ATTTAAATCA GGTCATAACT ACTACAGTGA TGAAACACAC 6360 CAAAATCTTC AGTβCCAATβ βACAAGTCAT TGAAGTCCAA TATGAAATCC TAAAGGCAAT 6420 TβCCTACTGG ATGACCATTC AATATGATAA TGTGGGCCGA CATβGTAATA TGTGCATAAG 6480 GGTAGGAGTA GATGCCAATA TAACAAGGTA CTTCTATGAA TACGATGCTβ ATGββCAACT 6540 TCAGACTGTT TCTβTAAATG ACAAAACCCA GTGGCGTTAT AGTTACGATC TβAATGGAGA 6600 CATCAACCTC TTAAGCCATG GGAAGAβTGC TCGTCTTACT CCTCTCCGAT ATGACCTCCG 6660 AGACCGCATC ACCAGATTAβ GAGAAATTCA GTATAAAATG GATGAAGATG GCTTTCTGAβ 6720 GCAGAGGGGA AATGATATTT TTGAATATAA TTCTAATGGC CTGCTGCAGA AAGCCTACAA 6780 TAAGGCTTCT GGCTGGACTG TGCAGTATTA CTATGATβββ CTTββGCGAC GTGTCGCGAG 6840 TAAGTCCAGC CTAGβGCAGC ACCTTCAGTT CTTTGTCGAC GCGACCGCGA ACCCCATAAG 6900 AGTTACTCAT TTGTACAACC ACACAAGCTC GGAGATTACA TCTCTGTATT ATGATCTCCA 6960 AGGTCACCTT ATTGCCATGG AGTTAAGCAG TGGTGAAGAA TATTATGTAG CCTβTGATAA 7020 TACAGGTACC CCACTAβCTG TGTTCAGCAβ CCGAGGTCAG GTCATAAAβG AGATACTATA 7080 CACACCTTAT GGCGATATCT ATCATGACAC TTACCCTGAC TTTCAGGTCA TAATTGGTTT 7140 TCATGGAGGA CTCTATGATT TCCTTACTAA ATTAGTGCAC CTGββGCAAA GGGATTATGA 7200 TGTTGTTGCT βGCAGATGGA CAACGGCCTA TCATCACATA TGGAAACAGT TGAACCTCCT 7260 TCCTAAACCA TTCAACCTCT ACTCCTTTGA AAATAACTAC CCAGTTGβCA AAATTCAAβA 7320 TGTTGCAAAG TATACCACAβ ACATCAGAAG TTGGTTGGAG CTATTTββTT TCCAATTACA 7380 CAATGTACTA CCTGGATTTC CCAAACCTGA ATTAGAAAAT TTAGAATTAA CTTACGAβCT 7440 TCTACGGCTT CAGACAAAAA CTCAAGAGTG GGATCCTGGA AAGACTATCC TGβGCATTCA 7500 GTGTGAACTC CAGAAACAGC TCAβGAATTT CATTTCCTTG GACCAACTAC CTATGACTCC 7560 CCGATACAAT GATGGACGβT GCCTTGAAβG AGGGAAGCAA CCAAGGTTTG CTGCTGTCCC 7620 TTCTGTTTTT GGGAAAGGTA TAAAATTTGC CATCAAGGAT GGCATAGTAA CAGCTGATAT 7680 TATAβGAGTA GCCAATGAAG ATAGCAGGCG GCTTGCTGCC ATTCTCAATA ATGCCCATTA 7740 CCTGGAAAAC CTACATTTTA CCATAGAGGG GAGGGACACT CACTACTTCA TTAAGCTTGG 7800 GTCTCTGβAG GAAGACCTGG TGCTCATCGG TAACACTGGβ GGGAGGCββA TTCTGβAGAA 7860 TGGTGTCAAT GTCACTGTGT CCCAβATGAC TTCTCTGTTG AATGGGAGGA CTAGACββTT 7920 TGCAGATATT CAGCTCCAGC ATGGAβCCCT GTGCTTCAAC ATCCGGTATG GGACAACTGT 7980 CGAAβAβGAA AAGAATCACG TGTTGGAGAT TGCCAGACAG CGCGCAGTGβ CCCAGGCCTβ 8040 βACTAAGGAA CAAAGAAGGC TGCAAGAββG GGAAGAGβGG ATTAGGGCAT GGACAGAAGG 8100 ββAAAAGCAG CAGCTTTTGA GCACTGGGCG GGTACAAGGT TACGATGGGT ATTTTGTTTT 8160 GTCTGTTGAG CAGTATTTAG AACTTTCTβA CAβTβCCAAT AATATTCACT TTATGAGACA 8220 GAGCGAAATA GGCAGGAGGT AACAAAAATA TCTCTGCCTT TGCGTCACCA AAGACTGCCT 8280 GTTTTTAAAA CATAAAATGG TTTATTβTAT TGGTTTTCTA GATCAGAACT CTGTATATGT 8340 AAATATββAG GAAAAACATA TCCAACTGCC TTTCAATGTG ACGGAAGATG GTATTTTAAT 8400 ATTGTTTβTT TAAACTCTTT AAβAAATβAC AGAGATTTTT AGTTCTTGTβ TGGCAβTATT 8460 CAAAATAACA CAAβTAGAAC TCAAACAGCT AAAAACAGTT TTCAGAAAGC ACCACTTTCA 8520 ATTTGCCGAG CCATGCATAT GTTCCAATAT CCAβAAAβAA CCCAAβGTTC TCTATCTCTA 8580 TTGTβAGAAG CAGTTTCATC CTTAACTGTT GGCAGAACTT ACGGGCTATT TβAATAGGTG 8640 GTβCAATAGT ATCTGAAACT TGCCTTTCGA AAGACTCCCA GCCCTTTGAC GTTTTCCAGA 8700 TCTGTTATAG GAAACTTAAA AACAβGTGTA AAATGTCTTC AGCCACCATC TCCTAβAβTβ 8760 AββACCCAAT TGCCCTTCCT TCTTGATTAT TCCTCCTTGC TTGTTAAAGT AAATβCCATA 8820 TTβTTGTGCT GTGTTTTGGC GTGTGGTGβC TGGGTTCTGT CTACCATGCT TCCCTβTββG 8880 TGTGGTAACC AGACTGTATA βCCGCTATTT GCTCGTGTGT ACATGATACC AAAGCAGCTG 8940 GCCAGCβTGA CCTCTCTCAC ACGACCTGTT TTβACTCAAT TTTTTACTAA AAβTTGTTCA 9000 GCTGTATTGG TATCATβTAA ACATAGCTTT TATTAACCTG GGTAGGAATT TCTCATTTAT 9060 ATATAGGATG TGTTTTGGTC ATAGTTTCAC ATTAGTGATT CAGTATCTAT ACACTGACCC 9120 AATGGTTTTG TGCACATGAA CGβTAATTTA CTTAAAAGTA TGATTCTGGT ACAAAAAGAA 9180 ACAAAGGCTT TAGCAGGCAT ACGTGTCTGG GATGCCGATA CATACATTAA CTACTACTGC 9240 AGAAATTCAT AAGAGCCAAA ACCTTAAAAA AATAGACCTG GTACTTAAGT GAAAGTACTA 9300 AAGGGAAGAC CAGACCAAAC ATCACAGCAG TTGCTGCCAC ATTGTTTCAβ CCCACTTAβA 9360 TTTATCTTTC AAATGTACAA TTCTGTATTG AACATCTCCC AGCCATCTTC AGGAAATCβA 9420 ATCAAGTAAA TCCTTTCCAA CCGAAAACAT TTCAACTAAC TATAGAGAGG CAGACTCATT 9480 TTTACTAAAA TAATTTATAC AGTTAGTTAT TTTCGTTCTC CGTACTTACC CATTTATCTT 9540 TATTTAATCβ TCTCTACTβC CTAGGAAAAT AACTATTTTC CAGGACGGGT TATTTGTTCT 9600 GCGATCATTT AAAATTTGGA GAAAGGTCAG GATTAβTGTT AATATCAGCT GCAGTTTCTC 9660 AATCTCTAGG AATCCTGCAG TAAAACAAGC CCCTTGGTGA GCTGGAAGAT TTGTGCCCAG 9720 TGACAAAGAG ATAGTTTGTA AAATGCTGTG TAATTβTAAG TTACCACAAA TGAAAATACA 9780 TGACAGCACA ATGTGGCCCG TAGAAAATTC CCCTβAβCCA βCTTCTGCAC TTTCATCACC 9840 GAATCTGAAC ATTTGCTATG TCTGAAGGCA AATTTATGAT GGAATGTTAG TTTGGATTCT 9900 TTCCAGATGC TACCTAAATG CAGTβTGGGG TCATTGCCTT GCTTTGCGAT GACAGTTTCT 9960 TTGAAAATAT GCAAAGTCAT AAβCTCATβT TAAGGTTTTT CAAGAGTCTG CCTCCTACTA 10020 CACAAAβGAA AGCAAGββAA AGGAAATGAC CCTGGCAAAC AβTAGGGAAG GGTGTATTCA 10080 AACATTTCAT TTTCAAAACC TTCGGGTTAG AATACCACTT ACACATGTAT TCTGAβAGAC 10140 AGAATTCATG AGGAACTCAT CTCTCTTTAT AACTββAAAC ACACCAβCTT GATATATTGC 10200 TAATCCATAC TAAAATCATA TTATTGββTT TTTTCTGAAT CAGGCCTGTA TTAATGGTAC 10260 AGTATTTATT CA6AATGGAA TTCTAAAATT ACTAACAAAC TTGTTGAAAA TTTGAATACC 10320 TCCACACCAA CCTAAAAATG GACCTTAAβT TCCTAβAACC TCTβATGTTC TTTTAAATTA 10380 ATGGAAAAAT AATTTGTGAA CTGTATATAβ AGAGTGCATT CATAAATβTβ ATTATβTATT 10440 TTATCACAAA TCCAAAATβT CAATATTAβA GTCTATTTTG CTTATATTTT AAGCAATTAT 10500 ACGTTTTTGC AATTCATTGA TGATGTATCA TTTTCAAACT GCTTTAAATA TCCATTAGAA 10560 ACAAATATTT GAAGCTTTTA CTTAATAGTG ATTACCTTGA ACTGTGCATT TCTAGTTTGT 10620 AATACGTATT TGGTTββTTC GTGCCTTTAβ TTTGTTAAAG TTACATTTGT ATTATATTCA 10680 GGAAATGCAC TTTTTATTAC TTACAGCTGT GGTTTTAATA CTβCCTTGAA CTATTATTAT 10740 TGTTTTTACA ACTCCTAAAG CTTGAGGGAG GAAAGAAAAA AAAAACAAAA CTACTAATCA 10800 GTAGTAAATC 6AAGAGAAAC ATTTTGGCAT TTCTTAAGAA GAAGATGGAG ATATTGAβTA 10860 TATCACTTCC TATTCAβCTβ AATAβAAAGA ATGCCTTCAT TGACTTGCAG TTCTGCAGTT 10920 TAAATTATTG AAAGAACAAT TCGTTTGCAT TTCCTGATGA AAGTAAAAβC ATTTTTCAβA 10980 GAAACATATG AATTTCTCAT ACCCAGCAβA CAGATGGCTG ACACTGCACA GCCACACACC 11040 ATTCGAGTAA GTTAAAGTGA GAGCATAGTA GTTGβACTCT CCTATGAAGA ACATTCTGGG 11100 CTGβAGGCAG GGAATACTCC ATGGTTGTTT CTTTTTCCTA CTTAAGCCCA TTTTβTTTGT 11160 GCTTTTCTGT TTTGTTTTGT TTTCACTCTT GCACTACAGT CTAGAGATCC AAATGAACTG 11220 AAAAGTTCAA AGTTTAACAC ATTTAAATAT GTTTACTTTT AGTTGTCATT CTAATCGTTA 11280 TTGATTAGAA GCATGACTCC TGAAGGAAAG GGAAATAAAT CTCAATTCAT ACTAACTTGC 11340 AACAAAACAC TTTTACCATA TAAATAAGTA TATGATTTAT TTTTAACCCA AAAAATGTAT 11400 AAAATAAGTG TGTCCTTTAC TGTCAATTTA TCGAGAAGAT CTATAATATA TAβACTACAT 11460 ATATATAATA TATACAACAT AGCCAAATGT ATGAAAACTT GACAATGTAT AATTTGGAAT 11520 TCACATGCTA CCTATGTAGA CAGGTATGAA ATTAAGTTAT AATTTTCATG AGACATTTTC 11580 ATCACTGTTG ACACAGTTTC AAGGCATTCC ATCATβTTAT TTTGACTCTT TTTCTTTTTT 11640 TTTTCTTTAA AAATATATTT TTAACTAGAC CAGGCCCCAC TATAATATCA CTTAAGAβAβ 11700 TCAGGGCAAA GTTTTTGCAT TTATβAAβAT GTGTTCATGT AAGGGTGATT GTAATββAβT 11760 TCATTGGTAA TAGAAGCAAA AGTACAGTAA CGAAGTATTG AAAAGAAAAT TTTGβAβACA 11820 TTGGAGCATA TTATATATAG CTTGTGGAAA GACATAAGGC TACAGATGβA ATGGAACATT 11880 CCTGTTTTCT TGAAGAAATT CACATACACA TAβCTGACCT GACTAGTACT TCAGCTCTTC 11940 CACAβCCTTC TATAAAββTT CTTTCTTCTβ CAAAGAAAAC AAAACAAAAC AAAACAAAAC 12000 AAAAAAAAAC AAAAAAAGCG CAAAAAACAA AAAAACAAAA AAAAGCAAAG TAAAATTTAA 12060 AAATACAGAA AACAAACAAC AAAAAAGAAT TCAACCATAA ATAGTGACTA TTATTTTCAG 12120 TGTGTCCTTC ATGTGAAAGC TATTAAGβAC CAAATATACT ACTβTTCATA AGAAβAAATT 12180 ACTTTCTAAA CAGTAACTGA AAATACTTAG AGTTAAACTT βCTGTGGATT TTGTCTTGGC 12240 AGTTβTCATC TTACATTATT TβTCAAAGGA AATGTGTTTG GCAGTTAAAA ATCTTTCCTT 12300 AGATTTAGTG GTGGACTTTA ACCTCTTAAA TAAATGTTAβ TATATCAGAT TGTGTCCTTG 12360 AAAAATATTT TACTTGTATG AATCATGACA ACGTCTAAAT CTTTACTATT CTTCTGGCAA 12420 AAGCATCAGT AAGAAAGAAG GCβAAAAAGA GAAGTATAGC CTTTATβTCA GAAAAACATT 12480 CTTTTTAGCT GCTTACTTTC TCATGAAAAG TAAAGATGTT TACAβTGTAT GCCAAGTTTT 12540 CAGTTTCTGT ATAACAACAG GTAβAGGTTC TAATCATATT GAAAATTGTG TTATAATGβT 12600 CTGAGCCATG TTGCTAGGAA ACAATAβGTT CCAATTTTβT ATTCCTCCTC TCCTGTGCTG 12660 AAAAGTGACT GβATACTGTA CAGβTTCATβ TTCTCTββCT GCAGTTAAAT GGTCTTTTGC 12720 ATTTTGCTCT GGCTTTCAGβ CCAGAAGCAT βCATTTTTCT ACAAGAGCAT CACAACAACA 12780 TGCTGTAAAT ATTTAAAGTT AAACATTATG TGTTGATATT TGAAAβAAAA GTACTTTGAA 12840 TATTTCATTT TTAAAAAATA AAATTGCCAA TGAAAAAAAA
A210 Protein sequence: βene name: odz (odd Oz/ten-m, Drosophila) homolog 1 Unigene number: Hs.23796 Probeset Accession ft: NM_014253 Protein Accession #: NP~055068 Signal sequence : none found Transmembrane domains: 318-340 Cellular Localization: plasma membrane
1 11 21 31 41 51
MEQTDCKPYQ PLPKVKHEMD LAYTSSSDES EDGRKPRQSY NSRETLHEYN QELRMNYNSQ 60
SRKRKEVEKS TQEMEFCETS HTLCSGYQTD MHSVSRHGYQ LEMGSDVDTE TEGAASPDHA 120
LRMWIRGMKS EHSSCLSSRA NSALSLTDTD HERKSDGENG FKFSPVCCDM EAQAGSTQDV 180
QSSPHNQFTF RPLPPPPPPP HACTCARKPP PAADSLQRRS MTTRSQPSPA APAPPTSTQD 240
SVH HNSWVL NSNIPLETRH SLFKHGSGSS AIFSAASQNY PLTSNTVYSP PPRPLPRSTF 300
SRPAFTFNKP YRCCNWKCTA LSATAITVTL ALLLAYVIAV HLFGLTWQLQ PVEGELYANG 360
VSKGNRβTES MDTTYSPIGG KVSDKSEKKV FQKGRAIDTG EVDIβAQVMQ TIPPGLFWRF 420
QITIHHPIYL KFNISLAKDS LLGIYGRRNI PPTHTQFDFV KLMDGKQLVK QDSKβSDDTQ 480
HSPRNLILTS LQETGFIEYM DQGPWYLAFY NDGKKMEQVF VLTTAIEIMD DCSTNCNGNG 540
ECISβHCHCF PGFLGPDCAR DSCPVLCGGN GEYEKGHCVC RHGWKβPECD VPEEQCIDPT 600
CFβHGTCIMG VCICVPGYKβ EICEEEDCLD PMCSNHβlCV KGECHCSTGW GGVNCETPLP 660
VCQEQCSGHG TFLLDAGVCS CDPKWTGSDC STELCTMECβ SHGVCSRGIC QCEEGWVGPT 720
CEERSCHSHC TEHGQCKDCK CECSPβWEGD HCTIAHYLDA VRDGCPGLCF βNGRCTLDQN 780
GWHCVCQVGW SGTGCNWME MLCGDNLDND GDGLTDCVDP DCCQQSNCYI SPLCQGSPDP 840
LDLIQQSQTL FSQHTSRLFY DRIKFLIGKD STHVIPPEVS FDSRRACVIR GQWAIDGTP 900
LVGVNVSFLH HSDYGFTISR QDGSFDLVAI GGISVILIFD RSPFLPEKRT LWLPWNQFIV 960
VEKVTMQRW SDPPSCDISN FISPNPIVLP SPLTSFGGSC PERGTIVPEL QWQEEIPIP 1020
SSFVRLSYLS SRTPGYKTLL RILLTHSTIP VGMIKVHLTV AVEβRLTQKW FPAAINLVYT 1080
FAWNKTDIYG QKVWGLAEAL VSVGYEYETC PDFILWEQRT WLQGFEMDA SNLGDWSLNK 1140
HHILNPQSGI IHKGNGENMF ISQQPPVIST IMGNGHQRSV ACTNCNGPAH NNKLFAPVAL 1200
ASGPDGSVYV GDFNFVRRIF PSGNSVSILE LSTSPAHKYY LAMDPVSESL YLSDTNTRKV 1260
YKLKSLVETK DLSKNFEWA GTGDQCLPFD QSHCGDGGRA SEASLNSPRG ITVDRHGFIY 1320
FVDβTMIRKI DENAVITTVI GSNGLTSTQP LSCDSGMDIT QVRLEWPTDL AVNPMDNSLY 1380
VLDNNIVLQI SENRRVRIIA GRPIHCQVPG IDHFLVSKVA IHSTLESARA ISVSHSGLLF 1440
IAETDERKVN RIQQVTTNGE I IIAGAPTD CDCKIDPNCD CFSGDGGYAK DAKMKAPSSL 1500
AVSPDβTLYV ADLGNVRIRT ISRNQAHLND MNIYEIASPA DQELYQFTVN GTHLHTLNLI 1560
TRDYVYNFTY NSEGDLGAIT SSNGNSVHIR RDAGGMPLWL WPGGQVYWL TISSNβVLKR 1620
VSAQGYNPAL MTYPGNTGLL ATKSNENGWT TVYEYDPEβH LTNATFPTGE VSSFHSDLEK 1680
LTKVELDTSN RENVLMSTNL TATSTIYILK QENTQSTYRV NPDβSLRVTF ASGMEIGLSS 1740
EPHILAGAVN PTLGKCNISL PGEHNANLIE WRQRKEQNKG NVSAFERRLR AHNRNLLSID 1800
FDHITRTGKI YDDHRKFTLR ILYDQTGRPI LWSPVSRYNE VNITYSPSGL VTFIQRGTWN 1860
EKMEYDQSGK IISRTWADGK IWSYTYLEKS VMLLLHSQRR YIFEYDQSDC LLSVTMPSMV 1920
RHSLQTMLSV GYYRNIYTPP DSSTSFIQDY SRDGRLLQTL HLGTβRRVLY KYTKQARLSE 1980
VLYDTTQVTL TYEESSGVIK TIHLMHDGFI CTIRYRQTGP LIGRQIFRFS EEGLVNARFD 2040
YSYNNFRVTS MQAVINETPL PIDLYRYVDV SGRTEQFGKF SVINYDLNQV ITTTVMKHTK 2100
IFSANβQVIE VQYEILKAIA YWMTIQYDNV GRHGNMCIRV GVDANITRYF YEYDADβQLQ 2160
TVSVNDKTQW RYSYDLNGDI NLLSHGKSAR LTPLRYDLRD RITRLGEIQY KMDEDGFLRQ 2220
RGNDIFEYNS NGLLQKAYNK ASGWTVQYYY DGLβRRVASK SSLGQHLQFF VDATANPIRV 2280
THLYNHTSSE ITSLYYDLQβ HLIAMELSSG EEYYVACDNT GTPLAVFSSR GQVIKEILYT 2340
PYGDI HDTY PDFQVIIβFH βGLYDFLTKL VHLGQRDYDV VAGRWTTAYH HIWKQLNLLP 2400
KPFNLYSFEN NYPVGKIQDV AKYTTDIRSW LELFGFQLHN VLPβFPKPEL ENLELTYELL 2460
RLQTKTQEWD PβKTILGIQC ELQKQLRNFI SLDQLPMTPR YNDGRCLEββ KQPRFAAVPS 2520
VFGKGIKFAI KDβlVTADII GVANEDSRRL AAILNNAHYL ENLHFTIEGR DTHYFIKLGS 2580
LEEDLVLIGN TGGRRILENG VNVTVSQMTS LLNGRTRRFA DIQLQHGALC FNIRYβTTVE 2640
EEKNHVLEIA RQRAVAQAWT KEQRRLQEβE EGIRAWTEGE KQQLLSTGRV QβYDβYFVLS 2700
VEQYLELSDS ANNIHFMRQS EIGRR
A211 DNA SEQUENCE: Gene name: Solute carrier family 26, member 4 Unigene number: Hs.159275 Probeset Accession #: AF030880 Nucleic Acid Accession #: NM_000441 Coding sequence: 225-2567 (underlined sequences correspond to start and εtop codonε)
11 21 31 41 51
CTCAGCCTTC CCGGTTCGGG AAAGGGGAAG AATGCAGGAG GGGTAGGATT TCTTTCCTGA 60 TAGGATCGGT TGGβAAAGAC CGCAGCCTβT GTGTGTCTTT CCCTTCGACC AAGGTGTCTG 120 TTGCTCCβTA AATAAAACGT CCCACTGCCT TCTGAGAGCG CTATAAAGGC AGCGGAAGGβ 180 TAGTCCGCGG GGCATTCCGG GCGGGGCGCβ AGCAGAGACA GGTCATGGCA GCGCCAGGCG 240 GCAGGTCGGA GCCGCCGCAG CTCCCCGAGT ACAGCTβCAβ CTACATGGTG TCGCGGCCGG 300 TCTACAGCβA GCTCGCTTTC CAGCAACAGC ACGAGCGGCG CCTGCAGGAG CGCAAGACGC 360 TGCGGGAGAG CCTGGCCAAG TGCTGCAGTT GTTCAAGAAA GAGAGCCTTT GGTGTGCTAA 420
AGACTCTTGT GCCCATCTTG βAβTGGCTCC CCAAATACCG AGTCAAGGAA TGGCTGCTTA 480
GTGACGTCAT TTCGGGAGTT AGTACTGGGC TAGTGGCCAC GCTCCAAGGG ATGGCATATG 540
CCCTACTAGC TβCAGTTCCT GTCGGATATG βTCTCTACTC TGCTTTTTTC CCTATCCTGA 600
CATACTTTAT CTTTGGAACA TCAAGACATA TCTCAGTTGβ ACCTTTTCCA βTGGTGAβTT 660
TAATGGTβGG ATCTGTTGTT CTGAGCATGG CCCCCGACGA ACACTTTCTC GTATCCAGCA 720 βCAATGGAAC TGTATTAAAT ACTACTATGA TAGACACTGC AGCTAGAGAT ACAGCTAGAG 780 TCCTGATTGC CAGTGCCCTG ACTCTβCTββ TTGGAATTAT ACAGTTGATA TTTGGTGGCT 840 TGCAGATTGG ATTCATAGTβ AGβTACTTGG CAGATCCTTT GGTTGβTββC TTCACAACAG 900 CTGCTGCCTT CCAAGTβCTβ GTCTCACAGC TAAAGATTGT CCTCAATGTT TCAACCAAAA 960
ACTACAATCβ AGTTCTCTCT ATTATCTATA CGCTGGTTGA GATTTTTCAA AATATTGGTG 1020
ATACCAATCT TGCTGATTTC ACTGCTGGAT TGCTCACCAT TGTCGTCTGT ATGGCAGTTA 1080
AGGAATTAAA TGATCGGTTT AGACACAAAA TCCCAGTCCC TATTCCTATA GAAGTAATTG 1140
TGACGATAAT TGCTACTGCC ATTTCATATG GAGCCAACCT ββAAAAAAAT TACAATGCTG 1200
GCATTGTTAA ATCCATCCCA AGGGGβTTTT TGCCTCCTGA ACTTCCACCT GTGAGCTTGT 1260
TCTCGGAβAT GCTGGCTGCA TCATTTTCCA TCGCTβTGGT βGCTTATGCT ATTGCAGTGT 1320
CAGTAGGAAA AβTATATβCC ACCAAβTATβ ATTACACCAT CGATβββAAC CAGGAATTCA 1380
TTGCCTTTGG GATCAGCAAC ATCTTCTCAG GATTCTTCTC TTGTTTTGTβ βCCACCACTG 1440
CTCTTTCCCG CACGGCCGTC CAGGAGAGCA CTGGAGGAAA GACACAβGTT GCTβGCATCA 1500
TCTCTGCTGC GATTGTGATG ATCGCCATTC TTGCCCTGGG GAAβCTTCTβ GAACCCTTGC 1560
AβAAβTCGGT CTTGGCAGCT GTTGTAATTG CCAACCTβAA AGGGATβTTT ATGCAβCTβT 1620
GTGACATTCC TCGTCTGTGG AGACAGAATA AGATTGATβC TβTTATCTβG GTβTTTACβT 1680
GTATAGTβTC CATCATTCTG GβGCTGβATC TCββTTTACT AGCTGGCCTT ATATTTGGAC 1740
TGTTGACTGT GGTCCTβAGA βTTCAβTTTC CTTCTTGGAA TGGCCTTGGA AGCATCCCTA 1800
GCACAGATAT CTACAAAAGT ACCAAGAATT ACAAAAACAT TGAAGAACCT CAAGGAGTGA 1860
AGATTCTTAG ATTTTCCAGT CCTATTTTCT ATGGCAATGT CGATGGTTTT AAAAAATGTA 1920
TCAAGTCCAC AGTTGGATTT GATGCCATTA GAGTATATAA TAAβAββCTβ AAAβCβCTβA 1980
GGAAAATACA GAAACTAATA AAAAGTGGAC AATTAAGAβC AACAAAβAAT GGCATCATAA 2040
GTGATGCTGT TTCAACAAAT AATGCTTTTG AGCCTGATGA GGATATTGAA βATCTGGAGG 2100
AACTTβATAT CCCAACCAAG GAAATAGAGA TTCAAGTGGA TTGGAACTCT GAβCTTCCAβ 2160
TCAAAβTGAA CGTTCCCAAA GTGCCAATCC ATAβCCTTβT GCTTβACTβT GGAβCTATAT 2220
CTTTCCTGGA CGTTGTTGGA GTGAGATCAC TGCGGGTβAT TGTCAAAGAA TTCCAAAβAA 2280
TTGATGTβAA TGTGTATTTT GCATCACTTC AAGATTATGT GATAGAAAAG 'CTGGAGCAAT 2340
GCGGGTTCTT TGACGACAAC ATTAGAAAββ ACACATTCTT TTTGACGGTC CATGATGCTA 2400
TACTCTATCT ACAGAACCAA GTGAAATCTC AAGAGGGTCA AGGTTCCATT TTAGAAACβA 2460
TCACTCTCAT TCAGGATTGT AAAGATACCC TTGAATTAAT AGAAACAGAG CTGACGGAAG 2520
AAGAACTTGA TβTCCAGGAT GAGGCTATGC GTACACTTGC ATCCTGAAAG TGGGTTCGGG 2580
AGGTCTCTAT GAGCAAGGAA TACAAGACAA AACTTCCTCA ATGCATTGAC TATTTCTTCA 2640
GACTCAAAAC ACTCATTCTT TTTTCTATTA AGCCATTGAA AGAGAAβCAC TAAGACTGCT 2700
TCTAGGCTTT ATTTATAAAA TAAACACCTT ATCCCTAACA TGGGCAAAAT GGCTAGAATT 2760
ATTCAGACGA TTTGGCAGCG TCCAGGGTAA GCTGGTGTTA TAATACGCTG CTGATCTACA 2820
TCACAGATTT GCTAATAATG TTCACGTGGG CCCTGGCATA TCTCTGTTCA GTTAGAGTGA 2880
GTGCTGACCC AACAGCCTCT GTGGTCAAGC GAGTCACGAA TGATTAATCA TAAAGAAAAA 2940
TCAGTTTTTG ACTGACCTGG ATATCCATGA GCTGCACTGA TCACCATGTA AGGTCACATT 3000
TAGTAAATGC TGAAATAAAA TGATTAATGC ATTTATCAAT AAAAGCCTTT GAAAATACTT 3060
TGGATAATAA ATTGGAGTTT TAAAAATGCA AATTTGCTTA GTATCTAATA ATGAAGTGTT 3120
ATTACATATA GCCGGAATTG AGGATCTCTT TGATCCTGGA AATGGTTTAC CTAAAAGCTA 3180
CAGAACCAGG CCAATATATT TTGAAATATT GATGCAGACA AATGAAATAA TAAAGAGATT 3240
TTCATGGTTT ATAAAAATCT TTTTTGATAT GATAATAATC ATGATCACAA CTGAβATCAA 3300
AAAAATATAT GACAGATTAT TTTGTTTAAA AATGCAGTTT TAATTATCTT AGTCTATAGA 3360
AATGATCATT GCATGGAGGC ATGTATAGGT ATGATCTGTG TAAAATCTGA CATAAAAACA 3420
GTGCTATTCT GAGTGAAAAT TTTTTTGATG TGCTTACATA ACCATGGTGA TTAAAATGAG 3480
TTTATATTTT TTCTCAAAAA TTTTAGCAGT GTGTAAAGTA AGTAATCTTT AACTGAACTC 3540
TGACCACTTA AAAAAAAATC TAAAAATTGA ACTACCTATA βTAGTCTGTG TTTAAAβTβA 3600
ATTTTTAAAG ACAAAβCATT CTAAATGAAC TCAATATAAA AACATTCATT TGGAATGTAC 3660
ATACTGAAAA ATACAGGTTT TTTTGACCAA AAGTTTTTAT ATCTTTTCTT TTTATTTATT 3720
TTTTTCCTAA GTGCCAACAA TTTTCTAGAT ATTATATACA ACACAGGCTT TGATCTTGGG 3780
GACTTTTCCC ATATATTTCA CACTGGAGTG AATGAAGTTG TACTTCATTT CTAGAGAAAA 3840
GTTATACCCA GGTCCCCAAT TGAGAATGTC TTGCTTGATT GAAAACGACA TCATCCCTTG 3900
GTATACTCCA GGGATTGGTT TCAGGACCCC TGCATTTACC AAAATTTβTG CACACTCAAG 3960
TCCTGCAGTC ACCCCTGCCT AAAGATAGAA TGGCTTCTCT GTTTTTCTTC TGAAATACAA 4020
CCAGAAACAA TGTGTCTATT TCTGAAAGAA TAGGATTAAT GATCATACAA ATGGGTTAAT 4080
CCTGAATTCT GGTTGTAAAT CTG TTACAG CATAACTAGG ATTATAATGC TGCCTCATTT 4140
TCACAGCACT ACTTGCTTAT ATTGACAACA AATCATCTCG CTAAAβAβTβ AATβTAββCC 4200
AGGCGCGGTG GCTCATGCCT GTAATCCCAβ CACTTTGGGA GGCCGAGGCG GβTββATCAC 4260
GAGGTCAGGA GATCGAGACC ATCCTGGCTA ACATGGTAAA ACCCCGTCTC TACTAAAAAT 4320
AGAAAAAAAG AAATTAGCCT AβCGTGGTGG CTGGCGGGCG CCTGTAGTCC CAGCTATTTβ 4380
GGAGGCTAAG GCAGGAGAAT GGCGTGAACC CGGGAGGCGG AGCTTGCAβT βAβCCGAGGT 4440
CGTGCCACTG CACTCCAGCC TGGGCβACAβ AβCAAGACTC CGTCTCAAAA AAAAAAAAAA 4500
AAAAAAAAAA AGAGTGAATβ TAATAGTCTT βCAβAAAATG AATGAATACC TTTGTTCAAT 4560
AAAGGAAATA TGCACTGCTC ACTTTTTTGA AGGAAATGCC AAAβTTACβT TTTACAACAA 4620
GGCTAGAGTT TGTAAATTCT GGGTTCATTT GTGATGACAT AAGTCAGCAA ACTGCGGGAA 4680
TACTGTCTCT TCTATGTATT TTGTGAATAG TAAGCATAAT TTTAGTTTTG TATTATCAAT 4740
GAAAATTTCA CTTGAAATTA AAGCTGCCTT TTGTTATATT TTTAACCTAT AGGATAAGAT 4800
TCCAGTATTG TATATGAGTT TTAACAAATT AAAAAATCAA ATCATGTACA TTTGAAAATA 4860
TTTGCACACA TTTAAAAATA AATGTAAAβT TβTCTTTTAA ACTACTCGGA TGTGTCCTTT 4920 CTGAACAAAA
A212 Protein εequence: Gene name : Solute carrier family 26 , member 4 Unigene number: Hs .159275 Probeset Accession if : AF030880 Protein Accession ft : 043511 Signal sequence: none found Transmembrane domains : 81-103 , 109-131 , 136-158 , 185-207 , 221-243 , 245-267 , 270-291 , 295-317 , 347-369 , 386-408 , 420-442 , 448-470 , 486-508 Cellular Localization: plasma membrane
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MAAPGGRSEP PQLPEYSCSY MVSRPVYSEL AFQQQHERRL QERKTLRESL A 1KCCSCSRKR 60 AFGVLKTLVP ILEWLPKYRV KEWLLSDVIS GVSTGLVATL QGMAYALLAA VPVβYβLYSA 120 FFPILTYFIF GTSRHISVGP FPWSLMVGS WLSMAPDEH FLVSSSNGTV LNTTMIDTAA 180 RDTARVLIAS ALTLLVGIIQ LIFGGLQIGF IVRYLADPLV GGFTTAAAFQ VLVSQLKIVL 240 NVSTKNYNGV LSIIYTLVEI FQNIGDTNLA DFTAGLLTIV VCMAVKELND RFRHKIPVPI 300 PIEVIVTIIA TAISYGANLE KNYNAGIVKS IPRGFLPPEL PPVSLFSEML AASFSIAWA 360 YAIAVSVGKV YATKYDYTID GNQEFIAFGI SNIFSGFFSC FVATTALSRT AVQESTGGKT 420 QVAGIISAAI VMIAILALGK LLEPLQKSVL AAWIANLKG MFMQLCDIPR LWRQNKIDAV 480 IWVFTCIVSI I GLDLGLLA GLIFGLLTW LRVQFPSWNG LGSIPSTDIY KSTKNYKNIE 540 EPQGVKILRF SSPIFYGNVD GFKKCIKSTV GFDAIRVYNK RLKALRKIQK LIKSGQLRAT 600 KNGIISDAVS TNNAFEPDED IEDLEELDIP TKEIEIQVDW NSELPVKVNV PKVPIHSLVL 660 DCGAISFLDV VGVRSLRVIV KEFQRIDVNV YFASLQDYVI EKLEQCGFFD DNIRKDTFFL 720 TVHDAILYLQ NQVKSQEGQG SILETITLIQ DCKDTLELIE TELTEEELDV QDEAMRTLAS 780 QDEAMRTLAS
A213 DNA SEQUENCE: Gene name: ESTs, Highly similar to calcium-activated potassium channel rSK2 [R.norvegicus] Unigene number: Hs.98280 Probeset Accession ft: AA418000 Nucleic Acid Accesεion it: NM_021614 Coding sequence: 458-2197 (underlined sequences correspond to start and stop codons)
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CGGCGGCAGC AGCCCATGCC TCCGGTGCAA CACCTGCβCC TCCTCCGGTG CCCCGGCGGC 60 GGGGGCGGGA GATAACCTGT CCCTGCTGCT CCβCACCTCC TCGCCCGGCG GCGCCTTCCG 120 GACCCGCACC TCCTCGCCGC TGTCGGGCTC GTCCTGCTGC TGCTGCTGCT GCTCGTCGCG 180 CCGGGGCAGC CAGCTCAATG TGAGCGAGCT βACβCCGTCC AGCCATGCCA GTGCGCTCCG 240 GCAβCACTAC GCGCAGCAGT CCGCGCAGCA GTCGGCGTCC GCCTCCCAGT ACCACCAGTG 300 CCACAGCCTG CAGCCCGCCG CCAβCCCCAC GGGCAGCCTC GGCAGTCTGG GCTCCGCGCC 360 CCCGCTCTCG CACCACCACC ACCACCCGCA CCCGGCGCAC CACCAGCACC ACCAGCCCCA 420 GGCGCGCCGC GAGAGCAACC CCTTCACCGA AATAGCCATG AGCAβCTGCA GGTACAACββ 480 GGGCβTCATG CGGCCβCTCA GCAACTTGAG CGCGTCCCGC CGGAACCTCC ACGAβATGGA 540 CTCAGAGGCG CAGCCCCTGC AGCCCCCCGC GTCTGTCGGA GGAGGTGβCβ GCβCβTCCTC 600 CCCGTCTβCA βACβCTGCCG CCGCCGCCGC TGTTTCGTCC TCAβCCCCCβ AβATCβTββT 660 GTCTAAGCCC GAβCACAACA ACTCCAACAA CCTGGCGCTC TATGβAACCG βCβGCGGAGβ 720 CAGCACTGGA GGAGGCβGCβ GCGGTGβAGG GAGCGGGCAC GβCAGCAβCA βTββCACCAA 780 βTCCAGCAAA AAGAAAAACC AGAACATCGG CTACAAGCTG GGCCACCGGC GCGCCCTβTT 840 CGAAAAG∞C AACCGGCTCA GCGACTACGC GCTCATCTTC GGCATβTTCG GCATCGTGGT 900 CATββTCATC GAGACCGAGC TGTCGTGGGG CGCCTACβAC AAGGCGTCGC TGTATTCCTT 960 AGCTCTGAAA TGCCTTATCA GTCTCTCCAC GATCATCCTG CTCGGTCTGA TCATCGTGTA 1020 CCACGCCAGβ GAAATACAGT TGTTCATGGT GGACAATGGA GCAGATGACT GGAGAATAGC 1080 CATGACTTAT GAGCβTATTT TCTTCATCTG CTTGGAAATA CTGGTβTβTβ CTATTCATCC 1140 CATACCTGGG AATTATACAT TCACATGGAC GGCCCGGCTT GCCTTCTCCT ATGCCCCATC 1200 CACAACCACC GCTGATGTGG ATATTATTTT ATCTATACCA ATGTTCTTAA GACTCTATCT 1260 GATTGCCAGA GTCATGCTTT TACATAGCAA ACTTTTCACT GATGCCTCCT CTAGAAGCAT 1320 TGβAβCACTT AATAAGATAA ACTTCAATAC ACGTTTTβTT ATGAAGACTT TAATGACTAT 1380 ATGCCCAββA ACTGTACTCT TGGTTTTTAG TATCTCATTA TGGATAATTG CCGCATGGAC 1440 TGTCCβAGCT TGTGAAAGGT ACCATGATCA ACAGGATGTT ACTAGCAACT TCCTTGGAGC 1500 βATGTGGTTβ ATATCAATAA CTTTTCTCTC CATTGGTTAT GGTGACATGG TACCTAACAC 1560 ATACTGTGGA AAAGGAGTCT GCTTACTTAC TGβAATTATβ GβTβCTβGTT GCACAGCCCT 1620 GGTGGTAGCT GTAGTGGCAA GGAAGCTAβA ACTTACCAAA GCAGAAAAAC ACGTGCACAA 1680 TTTCATGATG GATACTCAGC TGACTAAAAG AGTAAAAAAT GCAβCTβCCA ATGTACTCAβ 1740 GβAAACATGG CTAATTTACA AAAATACAAA GCTAGTGAAA AAβATAGATC ATGCAAAAGT 1800 AAGAAAACAT CAACGAAAAT TCCTGCAAGC TATTCATCAA TTAAGAAGTG TAAAAATGGA 1860 GCAGAGGAAA CTGAATβACC AAGCAAACAC TTTGGTGGAC TTGGCAAAGA CCCAGAACAT 1920 CATGTATGAT ATGATTTCTβ ACTTAAACGA AAGGAGTGAA GACTTCGAGA AGAGGATTGT 1980 TACCCTGGAA ACAAAACTAG AβACTTTGAT TGGTAGCATC CACGCCCTCC CTGGGCTCAT 2040 AAGCCAGACC ATCAGGCAGC AGCAGAβAGA TTTCATTGAβ GCTCAGATGG AGAGCTACGA 2100 CAAGCACGTC ACTTACAATG CTGAGCGGTC CCββTCCTCG TCCAGGAGGC GGCGGTCCTC 2160 TTCCACAGCA CCACCAACTT CATCAGAGAG TAGCTAGAAβ AGAATAAGTT AACCACAAAA 2220 TAAGACTTTT TGCCATCATA TGGTCAATAT TTTAGCTTTT ATTGTAAAGC CCCTATGGTT 2280 CTAATCAGCG TTATCCGGβT TCTGATGTCA GAATCCTGGG AACCTGAACA CTAAGTTTTA 2340 GGCCAAAATβ AβTβAAAACT CTTTCAGATG CACAGGβAAT GCACCTATTA 2400 TTGCTATATA GATTGTTCCT CCTGTAATTT CACTAACTTT TTATTCATGC ACTTCAAACA 2460 AACTTTACTA CTACATTATA . TβATATATAA TAAAAAAAGT TAATTTCGGA
A214 Protein sequence : Gene name : ESTs , Highly similar to calcium- activated potassium channel rSK2 [R.norvegicus Unigene number: Hs .98280 Probeset Accession : AA418000 Protein Accession # : NP_067627 Signal sequence : none found Transmembrane domains : 135-157 , 168-190 , 208-230 , 254-276 , 306-328 , 342-364 , 373-394 Calraodulin binding domain: 412-488 Cellular Localization: plasma membrane
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MSSCRYNGGV MRPLSNLSAS RRNLHEMDSE AQPLQPPASV GGGGGASSPS ADAAAAAAVS 60 SSAPEIWSK PEHNNSNNLA LYGTGGGGST GGGGGGGGSG HβSSSβTKSS KKKNQNIβYK 120 LGHRRALFEK RKRLSDYALI FGMFGIWMV IETELSWGAY DKASLYSLAL KCLISLSTII 180 LLGLIIVYHA REIQLFMVDN GADDWRIAMT YERIFFICLE ILVCAIHPIP GNYTFTWTAR 240 LAFSYAPSTT TADVDIILSI PMFLRLYLIA RVMLLHSKLF TDASSRSIGA LNKINFNTRF 300 VMKTLMTICP GTVLLVFSIS L IIAAWTVR ACERYHDQQD VTSNFLGAMW LISITFLSIG 360 YβDMVPNTYC GKβVCLLTGI MGAGCTALW AWARKLELT KAEKHVHNFM MDTQLTKRVK 420 NAAANVLRET WLIYKNTKLV KKIDHAKVRK HQRKFLQAIH QLRSVKMEQR KLNDQANTLV 480 DLAKTQNIMY DMISDLNERS EDFEKRIVTL ETKLETLIGS IHALPβLISQ TIRQQQRDFI 540 EAQMESYDKH VTYNAERSRS SSRRRRSSST APPTSSESS
A215 DNA SEQUENCE: βene name : CβI-86 protein Unigene number: Hs.109201 Probeεet Accession #: AW161450 Nucleic Acid Accession ft: NM_016029 Coding sequence : 228-1097 (underlined sequences correspond to start and stop codons)
31
CTβCβATCCC GCAGGGCAGC GACGCGACTC TGGTGCGββC CGTCTTCTTC CCCCCGAGCT 60
GGGCGTGCGC GGCCGCAATG AACTGGGAGC TGCTGCTGTβ GCTβCTCβTG CTGTGCGCGC 120
TGCTCCTGCT CTTGGTGCAG CTGCTGCGCT TCCTGAGG6C TGACββCGAC CTGACGCTAC 180
TATGGGCCGA GTGGCAGGGA CGACGCCCAG AATGββAβCT GACTGATATG GTGGTGTGGG 240
TGACTGGAGC CTCGAGTGGA ATTGGTGAGG AβCTGGCTTA CCAGTTGTCT AAACTAGβAG 300
TTTCTCTTGT GCTGTCAGCC AGAAGAGTGC ATGAGCTGGA AAGββTβAAA AGAAGATGCC 360
TAGAGAATβG CAATTTAAAA GAAAAAGATA TACTTGTTTT βCCCCTTβAC CTGACCGACA 420
CTGGTTCCCA TGAAβCGGCT ACCAAAGCTG TTCTCCAGGA βTTTββTAβA ATCGACATTC 480
TGGTCAACAA TGβTGGAATG TCCCAGCGTT CTCTGTGCAT GGATACCAGC TTGGATGTCT 540
ACAGAAAGCT AATAGAGCTT AACTACTTAG GGACGGTGTC CTTGACAAAA TGTGTTCTGC 600
CTCACATGAT CβAβAβGAAG CAAGGAAAGA TTGTTACTGT GAATAGCATC CTGGGTATCA 660
TATCTGTACC TCTTTCCATT GGATACTGTG CTAGCAAGCA TGCTCTCCββ GGTTTTTTTA 720
ATGGCCTTCG AACAGAACTT GCCACATACC CAGGTATAAT AGTTTCTAAC ATTTGCCCAG 780
GACCTGTGCA ATCAAATATT GTββAβAATT CCCTAGCTGG AGAAGTCACA AAβACTATAC 840
GCAATAATGG AGACCAGTCC CACAAβATGA CAACCAGTCG TTGTGTGCGG CTβATβTTAA 900
TCAGCATGGC CAATβATTTβ AAAGAAβTTT GGATCTCAGA ACAACCTTTC TTβTTAβTAA 960
CATATTTGTG GCAATACATG CCAACCTGGG CCTGβTGGAT AACCAACAAG ATGGββAAβA 1020
AAACβATTGA GAACTTTAAG AGTGβTβTGG ATGCAβACTC TTCTTATTTT AAAATCTTTA 1080
AGACAAAACA TGACTGAAAA GAGCACCTGT ACTTTTCAAG CCACTGGAGG GAGAAATββA 1140
AAACATβAAA ACAGCAATCT TCTTATGCTT CTGAATAATC AAAGACTAAT TTβTβATTTT 1200
ACTTTTTAAT AGATATGACT TTGCTTCCAA CATββAATβA AATAAAAAAT AAATAATAAA 1260
AGATTGCCAT GAATCTTGCA AA
A216 Protein sequence: Gene name: CGI-86 protem Unigene number: Hs.109201 . Probeset Accession ft : AW161450 Protein Accession ft: NP_057113 Signal sequence: 1-26 Transmembrane domains: 183-206, 221-243 Cellular Localization: plasma membrane
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MNWELLLWLL VLCALLLLLV QLLRFLRADG DLTLLWAEWQ GRRPEWELTD MWWVTGASS 60 βlGEELAYQL SKLGVSLVLS ARRVHELERV KRRCLENGNL KEKDILVLPL DLTDTGSHEA 120 ATKAVLQEFG RIDILVNNGG MSQRSLCMDT SLDVYRKLIE LNYLGTVSLT KCVLPHMIER 180 KQGKIVTVNS ILGIISVPLS IGYCASKHAL RGFFNGLRTE LATYPβlIVS NICPGPVQSN 240 IVENSLAGEV TKTIGNNGDQ SHKMTTSRCV RLMLISMAND LKEVWISEQP FLLVTYLWQY 300 MPTWAWWITN KMGKKRIENF KSGVDADSSY FKIFKTKHD
A217 DNA SEQUENCE: Gene name: Homo sapiens mRNA; cDNA DKFZp56401763 (from clone DKFZp56401763) Unigene number: Hs.27373 Probeset Accession ft: F13036 5 Nucleic Acid Accesεion ft: AC012478 Coding εequence: 1-1896 (underlined sequences correspond to start and stop codons) » 1 11 21 31 41 51 O I i i i i i
ATGCGCGCCβ TGCCGCTGCC CGCCCCGCTC CTGCCGCTGC TGCTβCTCβC GCTCCTGGCC 60
GCTCCCGCCG CCCGCGCCAG CAGAGCCGAG TCCGTCTCCG CGCCGTGGCC CGAACCCGAG 120
CGCGAGTCβC GGCCACCGCC CGGCCCGGGG CCCGGGAACA CCACCCGGTT TGGGTCTGGG 180
GCGGCGGGCG GCAGCGβCAβ CTCCAGCTCC AACAGCAGTG βCGACGCCTT GβTβACCCCC 240 ATTTCCATCC TCCTCCGCGA CCTACCCACC CTCAAGGCAG CCGTGATCGT GGCGTTCGCC 300
TTTACCACCC TCCTCATCGC CTGCCTCCTβ CTGCGCGTCT TCAGGTCGββ AAAGAGGTTA 360
AAGAAGACAC βCAAβTATGA TATCATCACC ACTCCAβCAβ AβCGAGTβGA AATGGCGCCA 420
CTAAATGAAG AGGATGATGA AβATGAGβAC TCCACAGTAT TCGACATCAA ATACAGAGTG 480
TCCTTGCCββ CTGCACTGAG ACCTCAGCTG CCA6GGTGCC AGACGCTACT GACAGTTCCT 540 βTGCCCCCAC CCTTCATCCT CGACATTGAC CTTCCAGCAA GATGCAGTGG AAGGCCTGAT 600
GGTGGAATCA GACCTGGTAA AACCTGTTTC CCAGCCTGGT GGCATCCTGT GGAAAGTTGG 660
TCAGCTGCAA CCTGGGβTβT GAAβGACTGG ACCTGGAAGC CCTCTTGCGT CGGAGGTGTT 720
GAAACCAAAA CGAACGTTAT βTATAAAACC CCAGCTCCAT CGTGCβTGTC AGGCATCTGC 780
TCAGACTGTC ACTGGCAAGC TCβTTTCCAC GTCACCACAA TGGAβTTGCT TCTGCCACCC 840
TTTGGGCATC CCTTTAAAGT GCCCCCTACT TCTACTCCCC ATGGTTTTCβ ACAACTβCAβ 900
CTGAATCTCA TGGAAAAGCT GGATTCCTCT GCCTTACGCA GAAACACCCG GGCTCCATCT 960
GCCAGGTGCT TGCCACTGGT CCTGGCAGAA ATGGCGGCTβ CTβAAAGTGA CCTTCCAAAT 1020
CCTTGGTGGC ACTTCAGCGC CACAGGCTCT CCAATAAAAA CCCTTTACAC ACAAACCATG 1080
AGTACCTTGG GCTTGGATGT TTTCTGTGGT βCCβGCCAGC GGGGCACCTT TTGTGAA6AC 1140
AGAGCAGTGA CTAAGGTTCT CCAGGGTAGC TCTTTCTCCA AACAGCTβCβ CTGGAAGCCA 1200
GCCCTAGAGA GTGGGTTTCC CCATCATCTC AGGCTTCTCA GAGAGTGTCC TCCGCTGAGC 1260
ACCCATCCTG TCAGβTTβGC TCGTTCAGAT GCCCGGGGAC AAGCCAGCCT GACGGGGAGG 1320
AGGGTGTTTC GGCβTCCGCG GCAGTCTCTG CATGGCGβAβ GβTCAGCGGG TACCGCAACT 1380
TGCCTTTTGβ TTTTGAAGAT TCTGTTGAGG CGCCATCCTC ACCTTGACCT CTTCTACAAA 1440
ATCTGTCTCC CCTGCTGTGC CGTGGAACAC CTACGGGAAβ CCAAGAGAAG CTCAGTGACT 1500
GTCCTTGCGT CATTTGAGCA GAGCCCACAA AAββCAβCTG CTGCCCACGG GGAGCCTGTC 1560
AAACGAGGβC CCAGTGGGCA ATTGACCAβA CACACATGCC CTGGCTβGGG GATCACACAT 1620
GCGAACCTGC AGACAATTCC AβATACCCAA GGCCAGGAAG GCCCACGTGA GGATGTCACT 1680
CACCCTGGAG GAGACTTGGA TGGGGTGGCA AATTTCTATT TGβAββAAGA GGβTTTCCAβ 1740
GATGGCAβAT GCCA6AAGAT GGTCCTGATG TCTGAGGAAβ ββCCACCTAG TTTGACAβGA 1800
TGTGAGAGGC TCACAGGTTC CCATCACTTC TCCAβCCATT CCAAGTCTTG GTCCTTCCTT 1860
TCCCCCCGAC AGCCCCTGTT TCTGTCCAββ CCCTβA
A218 Protein sequence: Gene name : Homo sapiens mRNA; CDNA DKFZp56401763 (from clone DKFZp56401763) Unigene number: Hs.27373 Probeset Acceεεion ft: F13036 Protein Accession ft: FGENESH predicted Signal sequence : 1-27 Transmembrane domains: 94-115, 448-469 Cellular Localization: not determined
60
120
Figure imgf000936_0001
180
VPPPFILDID LPARCSGRPD GGIRPGKTCF PAWWHPVESW SAATWGVKDW TWKPSCVGGV 240
ETKTNVMYKT PAPSCVSGIC SDCHWQARFH VTTMELLLPP FGHPFKVPPT STPHGFRQLQ 300
LNLMEKLDSS ALRRNTRAPS ARCLPLVLAE MAAAESDLPN PWWHFSATGS PIKTLYTQTM 360
STLGLDVFCG AGQRGTFCED RAVTKVLQGS SFSKQLRWKP ALESGFPHHL RLLRECPPLS 420
THPVRLARSD ARGQASLTGR RVFRRPRQSL HGGGSAGTAT CLLVLKILLR RHPHLDLFYK 480
ICLPCCAVEH LREAKRSSVT VLASFEQSPQ KAAAAHGEPV KRGPSβQLTR HTCPβWβlTH 540
ANLQTIPDTQ GQEGPREDVT HPGGDLDGVA NFYLEEEGFQ DβRCQKMVLM SEEGPPSLTG 600
CERLTGSHHF SSHSKSWSFL SPRQPLFLSR P
A219 DNA SEQUENCE
Gene name: selectin E (endothelial adhesion molecule 1)
Unigene number: Hs.89546
Probeset Accession ft: M24736
Nucleic Acid Accession ft: NM_000450
Coding sequence: 1-1833 (underlined sequences correspond to start and stop codons)
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ATGATTGCTT CACAGTTTCT CTCAGCTCTC ACTTTGGTGC TTCTCATTAA AGAGAGTGGA 60 GCCTGGTCTT ACAACACCTC CACGGAAβCT ATGACTTATG ATGAGGCCAG TGCTTATTGT 120 CAGCAAAGGT ACACACACCT GGTTGCAATT CAAAACAAAG AAGAGATTGA GTACCTAAAC 180 TCCATATTGA GCTATTCACC AAGTTATTAC TββATTβGAA TCAGAAAAGT CAACAATGTG 240 TGGGTCTGGG TAGβAACCCA GAAACCTCTG ACAGAAGAAG CCAAGAACTG GGCTCCAGGT 300 GAACCCAACA ATAGGCAAAA AGATGAGGAC TGCGTGGAGA TCTACATCAA GAGAGAAAAA 360 GATGTGGGCA TGTGGAATGA TGAGAGGTGC AGCAAGAAGA AGCTTGCCCT ATGCTACACA 420 GCTGCCTGTA CCAATACATC CTGCAGTGGC CACGGTGAAT GTGTAGAGAC CATCAATAAT 480 TACACTTGCA AGTGTGACCC TGGCTTCAGT GGACTCAAβT GTGAGCAAAT TGTGAACTGT 540 ACAGCCCTGG AATCCCCTGA GCATGGAAGC CTβGTTTGCA GTCACCCACT GGGAAACTTC 600 AGCTACAATT CTTCCTGCTC TATCAGCTβT GATAGGGGTT ACCTGCCAAβ CAGCATGGAβ 660 ACCATGCAβT GTATβTCCTC TGGAGAATββ AGTGCTCCTA TTCCAGCCTG CAATGTββTT 720 GAGTGTGATβ CTGTGACAAA TCCAβCCAAT GGGTTCGTGG AATGTTTCCA AAACCCTβGA 780 AGCTTCCCAT GGAACACAAC CTGTACATTT GACTGTGAAβ AAGGATTTGA ACTAATGGβA 840 GCCCAGAGCC TTCAGTGTAC CTCATCTGGG AATTGGGACA ACGAβAAβCC AACGTGTAAA 900 GCTGTGACAT GCAGGGCCGT CCGCCAGCCT CAβAATGGCT CTGTGAβGTG CAGCCATTCC 960 CCTGCTGβAG AGTTCACCTT CAAATCATCC TGCAACTTCA CCTGTGAGGA AGGCTTCATG 1020 TTGCAGGGAC CAGCCCAGGT TGAATGCACC ACTCAAGββC AGTGGACACA GCAAATCCCA 1080 GTTTGTGAAG CTTTCCAGTG CACAGCCTTG TCCAACCCCG AGCβAGGCTA CATGAATTGT 1140 CTTCCTAGTG CTTCTGGCAβ TTTCCGTTAT GGGTCCAGCT GTGAGTTCTC CTGTGAGCAG 1200 GGTTTTGTGT TGAAGGGATC CAAAAGGCTC CAATGTGGCC CCACAβGGGA GTGGGACAAC 1260 GAGAAGCCCA CATGTGAAGC TGTGAGATGC GATGCTGTCC ACCAGCCCCC GAAGGGTTTG 1320 GTGAGGTβTβ CTCATTCCCC TATTGGAGAA TTCACCTACA AGTCCTCTTG TGCCTTCAGC 1380 TGTGAGGAGG GATTTGAATT ATATGGATCA ACTCAACTTG AGTGCACATC TCAGGGACAA 1440 TGGACAGAAG AGGTTCCTTC CTGCCAAGTG GTAAAATβTT CAAGCCTGGC AGTTCCGGGA 1500 AAGATCAACA TGAGCTGCAG TGGGGAGCCC βTβTTTGGCA CTGTβTGCAA GTTCGCCTGT 1560 CCTGAAGGAT GGACGCTCAA TGGCTCTGCA GCTCGGACAT GTββAβCCAC AGGACACTGG 1620 TCTGGCCTGC TACCTACCTG TGAAGCTCCC ACTGAGTCCA ACATTCCCTT GGTAGCTGGA 1680 CTTTCTGCTG CTGGACTCTC CCTCCTGACA TTAGCACCAT TTCTCCTCTβ GCTTCGGAAA 1740 TGCTTACGGA AAGCAAAGAA ATTTGTTCCT GCCAGCAGCT GCCAAAGCCT TGAATCAGAC 1800 GGAAGCTACC AAAAGCCTTC TTACATCCTT TAA
A220 Protein sequence: Gene name: Selectin E (endothelial adhesion molecule 1) Unigene number: Hs.89546 Probeset Accession ft: M24736 Protein Accession ft: NP_000441 Signal sequence : 1-22 Transmembrane domainε: 555-573 C-lectin domain: 23-139 Cellular Localization: plasma membrane
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MIASQFLSAL TLVLLIKESG AWSYNTSTEA MTYDEASAYC QQRYTHLVAI QNKEEIEYLN 60 SILSYSPSYY WIGIRKVNNV WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK 120 DVGMWNDERC SKKKLALCYT AACTNTSCSG HGECVETINN YTCKCDPGFS GLKCEQIVNC 180 TALESPEHGS LVCSHPLGNF SYNSSCSISC DRGYLPSSME TMQCMSSGEW SAPIPACNW 240 ECDAVTNPAN GFVECFQNPG SFPWNTTCTF DCEEGFELMG AQSLQCTSSG NWDNEKPTCK 300 AVTCRAVRQP QNGSVRCSHS PAβEFTFKSS CNFTCEEGFM LQGPAQVECT TQβQWTQQIP 360 VCEAFQCTAL SNPERGYMNC LPSASGSFRY GSSCEFSCEQ GFVLKGSKRL QCGPTGEWDN 420 EKPTCEAVRC DAVHQPPKGL VRCAHSPIGE FTYKSSCAFS CEEGFELYGS TQLECTSQGQ 480 WTEEVPSCQV VKCSSLAVPβ KINMSCSGEP VFβTVCKFAC PEGWTLNGSA ARTCGATGHW 540 SGLLPTCEAP TESNIPLVAβ LSAAGLSLLT LAPFLLWLRK CLRKAKKFVP ASSCQSLESD 600 GSYQKPSYIL
Taxol Prostate
A221 DNA SEQUENCE Gene name: ESTs; Liprin A2 Unigene number: Hs.306480 Probeset Accession ft: N51002 Nucleic Acid Accession ft: N51002
Coding sequence: 1-3793 (underlined sequenceε correspond to start and stop codons)
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ATGATβTGT AAGTGATGCC CACGATTAAT GA6GACACCC CAATGAGCCA AAGGGGGTCC 60 CAAAGCAGTG GCTCGGACTC AGACTCCCAT TTTGAGCAGC TGATGβTβAA TATGCTAGAT 120 GAAAGGGATC GTCTTCTAGA CACCCTTCGG GAGACCCAGG AAAGCCTCTC ACTTGCCCAG 180 CAAAGACTTC AGGATGTCAT CTATGACCGA GACTCACTCC AGAGACAGCT CAATTCAGCC 240 CTGCCACAGG ATATCGAATC CCTAACAGGA GGGCTGGCTG βTTCTAAGGG GGCTGATCCA 300 CCGGAATTTG CTGCACTGAC AAAAGAATTA AATGCCTGCA GGGAACAACT TCTAGAAAAG 360 GAAGAAGAAA TCTCTGAACT TAAAGCTGAA AGAAACAACA CAAGACTATT ACTGGAGCAT 420 TTGGAGTGCC TTGTGTCACG ACATGAAAGA TCACTAAGAA TGACGGTβGT AAAACGGCAA 480 GCCCAGTCTC CCTCAGGAGT ATCCAGTGAA GTTGAAGTTC TCAAGGCACT GAAATCTTTG 540 TTTGAβCACC ACAAGGCCTT GGATGAAAAG GTAAGGGAGC GACTGAGGGT TTCTTTAGAA 600 AGAGTCTCTG CACTGGAAGA AGAACTAGCT GCTGCTAATC AGGAGATTGT TGCCTTGCGT 660 GAACAAAATβ TTCATATACA AAGAAAAATG GCATCAAGCβ AGGGATCCAC AGAGTCAGAA 720 CATCTTGAAG GGATGGAACC TGGACAGAAA GTCCATGAGA AGCGTTTGTC CAATGGTTCT 780 ATAGACTCAA CCGATGAAAC TAGTCAAATA GTTGAACTAC AAβAATTβCT TGAAAAGCAA 840 AACTATGAAA TGGCCCAGAT GAAAβAACGT TTAβCAGCCC TTTCTTCCCG AGTGGGAGAG 900 GTGGAACAGβ AAGCAGAGAC AGCAAGAAAG GATCTCATTA AAACAGAAGA AATGAACACC 960 AAGTATCAAA GββACATTAβ βGAGGCCATG GCACAAAAGβ AAGATATGGA AβAAAGAATT 1020 ACAACCCTTG AAAAGCGTTA CCTCAGTβCT CAGAGAGAAT CTACCTCCAT ACATGACATG 1080 AATGATAAAC TAGAAAATGA GTTAGCAAAT AAAGAAGCTA TCCTACGGCA GATGGAAGAβ 1140 AAAAACAGAC AGTTACAAGA ACGTCTTGAG CTAGCTGAAC AAAAβTTβCA GCAGACCATG 1200 AGAAAGGCTG AAACCTTGCC TGAAGTAGAG GCTGAACTββ CTCAGAGAAT TGCAGCCCTA 1260 ACCAAGGCTG AAGAβAGACA TGGAAATATT GAAGAACGTA TGAGACATTT AGAGGGTCAA 1320 CTTGAAGAGA AGAATCAAGA ACTTCAAAGA GCTAGGCAAA GAGAGAAAAT GAATGAβGAG 1380 CATAACAAGA βATTATCGGA TACGGTTGAT AGACTTCTβA CTGAATCCAA TGAACβCCTA 1440 CAACTACACT TAAAβGAAAG AATGGCTGCT CTAGAAGAAA AGAATGTTTT AATTCAAβAA 1500 TCAGAAACTT TCAβAAAGAA TCTTGAAGAA TCTTTACATG ATAAGGAAAG ATTAGCAGAA 1560 GAAATTGAAA AGCTGAGATC TGAACTTGAC CAATTβAAAA TGAGAACTGG CTCTTTAATT 1620 GAACCCACAA TACCAAGAAC TCATCTAGAC ACCTCAβCTG AGTTGCGGTA CTCAGTGGGA 1680 TCCCTAGTGG ACAGCCAGTC TGATTACAGA ACAACTAAAG TAATAAGAAG ACCAAGGA6A 1740 GGCCGCATGG GTβTGCGAAG AGATGAGCCA AAGGTGAAAT CTCTTGGGGA TCACGAGTββ 1800 AATAGAACTC AACAGATTGG AGTACTAAGC AGCCACCCTT TTGAAAGTGA CACTGAAATG 1860 TCTGATATTG ATGATGATGA CAGAβAAACA ATTTTTAGCT CAATGGATCT TCTCTCTCCA 1920 AGTGGTCATT CCGATGCCCA βACGCTAGCC ATGATGCTTC AGGAACAATT GGATGCCATC 1980 AACAAAGAAA TCAβGCTAAT TCAGGAAGAA AAAGAATCTA CAGAβTTGCG TGCTGAAGAA 2040 ATTGAAAATA GAGTGGCTAG TGTGAGCCTC GAAββCCTGA ATTTββCAAβ GGTCCACCCA 2100 GGTACCTCCA TTACTβCCTC TGTTACAGCT TCATCGCTGG CCAGTTCATC TCCCCCCAGT 2160
GGACACTCAA CTCCAAAGCT CACCCCTCGA AGCCCTGCCA GGGAAATGGA TCGGATGββA 2220
GTCATGACAC TGCCAAGTGA TCTGAβGAAA CATCGGAGAA AGATTGCAGT TGTGGAAGAA 2280
GATGGTCβAG AGGACAAAGC AACAATTAAA TGTGAAACTT CTCCTCCTCC TACCCCTAGA 2340
GCCCTCAGAA TGACTCACAC TCTCCCTTCT TCCTACCACA ATGATGCTCG AAGTAβTTTA 2400
TCTβTCTCTC TTGAGCCAGA AAGCCTCGGG CTTGGTAβTβ CCAACAGCAG CCAAGACTCT 2460
CTTCACAAAG CCCCCAAGAA GAAAGβAATC AAβTCTTCAA TAGGACGTTT GTTTββTAAA 2520
AAAGAAAAAG CTCGACTTGG GCAβCTCCGA GGCTTTATGG AGACTGAAGC TβCAβCTCAG 2580
GAGTCCCTGG GGTTAGGCAA ACTCGGAACT CAAGCTβAGA AGGATCGAAG ACTAAAGAAA 2640
AAGCATGAAC TTCTTGAAGA AGCTCGGAGA AAGGGATTAC CTTTTGCCCA GTGGGATGββ 2700
CCAACTGTGβ TCβCATGGCT AGAβCTTTGG TTGGGAATGC CTGCGTβGTA CβTββCAGCC 2760
TGCCGAGCCA ACβTGAAGAβ TGβTβCCATC ATGTCTGCTT TATCTGACAC TβAβATCCAβ 2820
AGAGAAATTβ βAATCAβCAA TCCACTβCAT CGCTTAAAAC TTCβATTAGC AATCCAGGAβ 2880
ATGGTTTCCC TAACAAGTCC TTCAβCTCCT CCAACATCTC GAACTCCTTC AGGCAACGTT 2940
TββGTGACTC ATβAAβAAAT GGAAAATCTT GCAGCTCCAG CAAAAACGAA AGAATCTGAG 3000
GAAGGAAGCT GGβCCCAβTβ TccσβTTTTT CTACAGACCC TGβCTTATGG AGATATGAAT 3060
CATGAGTGβA TTββAAATGA ATGGCTTCCC AGCTTGGGGT TACCTCAβTA CAGAAβTTAC 3120
TTTATGGAAT GCTTGGTAGA TGCAAGAATG TTAGATCACC TAACAAAAAA AGATCTCCGT 3180
GTCCATTTAA AAATββTββA TAGTTTCCAT CGAACAAGTT TACAATATGG AATTATGTGC 3240
TTAAAβAβGT TGAATTATβA CAGAAAAGAA CTAGAAAGAA GACGGGAAGC AAGCCAACAT 3300
GAAATAAAAG ACβTβTTGβT βTββAβCAAT GACCGAATTA TTCGCTGGAT ACAAGCAATT 3360
GGACTTCGAG AATATGCAAA TAATATACTT GAGAGCGGTG TGCATGGCTC ACTTATAGCC 3420
CTGGATGAAA ACTTTGACTA CAGCAGCTTA ACTTTATTAT TACAGATTCC AACACAGAAC 3480
ACCCAGGCAA GGCAGATTCT TGAAAGAGAA TACAATAACC TCTTGGCCCT GGβAACTGAA 3540
AGGCGACTGG ATGAAAGTGA TGACAAGAAC TTCAGACGTG GATCAACCTG GAGAAββCAβ 3600
TTTCCTCCTC GTGAAGTACA TGGAATCACC ATGATGCCTG GGTCCTCAGA AACATTACCA 3660 βCTβGATTTA GβTTAACCAC AACCTCTβGG CAATCAAGAA AAATGACAAC AGATGTTGCT 3720
TCATCAAβAC TGCAGAGGTT AGACAACTCC ACTGTTCGCA CATACTCATG TCTCGAGTAA 3780
GCGGCCGCTT TAA
A222 Protein sequence
Gene name: ESTs; Liprin A2
Unigene number: HS.30648C 1
Probeset Accession ft : N51002
Protein Accession ft: none found
Signal sequence : none found
Transmembrane domains : none found
AAA domain: 286-539
SAM domains: 895-964, 1017-1084, 1105-1177
Cellular Localization : not determined
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MMCEVMPTIN EDTPMSQRGS QSSGSDSDSH FEQLMVNMLD ERDRLLDTLR ETQESLSLAQ 60 QRLQDVIYDR DSLQRQLNSA LPQDIESLTβ GLAGSKGADP PEFAALTKEL NACREQLLEK 120 EEEISELKAE RNNTRLLLEH LECLVSRHER SLRMTWKRQ AQSPSGVSSE VEVLKALKSL 180 FEHHKALDEK VRERLRVSLE RVSALEEELA AANQEIVALR EQNVHIQRKM ASSEGSTESE 240 HLEGMEPGQK VHEKRLSNβS IDSTDETΞQI VELQELLEKQ NYEMAQMKER LAALSSRVGE 300 VEQEAETARK DLIKTEEMNT KYQRDIREAM AQKEDMEERI TTLEKRYLSA QRESTSIHDM 360 NDKLENELAN KEAILRQMEE KNRQLQERLE LAEQKLQQTM RKAETLPEVE AELAQRIAAL 420 TKAEERHGNI EERMRHLEβQ LEEKNQELQR ARQREKMNEE HNKRLSDTVD RLLTESNERL 480 QLHLKERMAA LEEKNVLIQE SETFRKNLEE SLHDKERLAE EIEKLRSELD QLKMRTGSLI 540 EPTIPRTHLD TSAELRYSVG SLVDSQSDYR TTKVIRRPRR GRMGVRRDEP KVKSLGDHEW 600 NRTQQIβVLS SHPFESDTEM SDIDDDDRET IFSSMDLLSP SGHSDAQTLA MMLQEQLDAI 660 NKEIRLIQEE KESTELRAEE IENRVASVSL EGLNLARVHP GTSITASVTA SSLASSSPPS 720 GHSTPKLTPR SPAREMDRMG VMTLPSDLRK HRRKIAWEE DGREDKATIK CETSPPPTPR 780 ALRMTHTLPS SYHNDARSSL SVSLEPESLβ LGSANSSQDS LHKAPKKKGI KSSIGRLFGK 840 KEKARLgQLR GFMETEAAAQ ESLβLβKLβT QAEKDRRLKK KHELLEEARR KGLPFAQWDG 900 PTWAWLELW LβMPAWYVAA CRANVKSGAI MSALSDTEIQ REIGISNPLH RLKLRLAIQE 960 MVSLTSPSAP PTSRTPSGNV WVTHEEMENL AAPAKTKESE EGSWAQCPVF LQTLAYGDMN 1020 HEWIGNEWLP SLGLPQYRSY FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC 1080 LKRLNYDRKE LERRREASQH EIKDVLVWSN DRIIRWIQAI GLREYANNIL ESGVHGSLIA 1140 LDENFDYSSL TLLLQIPTQN TQARQILERE YNNLLALβTE RRLDESDDKN FRRGSTWRRQ 1200 FPPREVHGIS MMPGSSETLP AGFRLTTTSG QSRKMTTDVA SSRLQRLDNS TVRTYSCLE
A223 DNA SEQUENCE
Gene name: CDA14
Unigene number: Hs.26813
Probeset Acceεsion ft: N32912
Nucleic Acid Accession #-. NM_016570
Coding sequence: 1- 1134 (underlined sequences correspond to εtart and stop codons)
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I I I I I
ATGAββCGAC TGAATCGGAA AAAAACTTTA AGTTTββTAA AAGAGTTGGA TGCCTTTCCG 60 AAββTTCCTG AGAβCTATGT AGAGACTTCA GCCAGTββAβ GTACAGTTTC TCTAATAGCA 120 TTTACAACTA TGGCTTTATT AACCATAATG GAATTCTCAG TATATCAAGA TACATGGATG 180 AAGTATGAAT ACGAAGTAGA CAAGGATTTT TCTAGCAAAT TAAGAATTAA TATAGATATT 240 ACTGTTβCCA TGAAGTGTCA ATATGTTGGA GCGGATGTAT TGGATTTAGC AGAAACAATG 300 GTTGCATCTG CAGATGGTTT AGTTTATGAA CCAACAβTAT TTGATCTTTC ACCACAGCAG 360 AAAGAGTGGC AGAGGATGCT GCAGCTGATT CAβAβTAGGC TACAAGAAGA GCATTCACTT 420 CAAGATβTGA TATTTAAAAG TGCTTTTAAA AGTACATCAA CAGCTCTTCC ACCAAGAGAA 480 GATGATTCAT CACAβTCTCC AAATGCATGC AGAATTCATG GCCATCTATA TGTCAATAAA 540
GTAGCAGGGA ATTTTCACAT AACAGTGGGC AAGβCAATTC CACATCCTCG TGGTCATGCA 600
CATTTGGCAG CACTTGTCAA CCATGAATCT TACAATTTTT CTCATAβAAT AGATCATTTG 660
TCTTTTGGAG AGCTTGTTCC AGCAATTATT AATCCTTTAβ ATGGAACTGA AAAAATTGCT 720
ATAGATCACA ACCAGATGTT CCAATATTTT ATTACAGTTG TGCCAACAAA ACTACATACA 780
TATAAAATAT CAGCAGACAC CCATCAGTTT TCTGTGACAβ AAAGGGAACG TATCATTAAC 840
CATGCTGCAG GCAGCCATGG AGTCTCTGGG ATATTTATβA AATATGATCT CAGTTCTCTT 900
ATGGTβACAG TTACTGAGGA GCACATGCCA TTCTGGCAGT TTTTTGTAAβ ACTCTGTGGT 960
ATTGTTGGAG GAATCTTTTC AACAACAGGC AT6TTACATG GAATTGGAAA ATTTATAGTT 1020
GAAATAATTT GCTGTCGTTT CAGACTTGGA TCCTATAAAC CTGTCAATTC TGTTCCTTTT 1080
GAGGATββCC ACACAGACAA CCACTTACCT CTTTTAGAAA ATAATACACA TTGA
A224 Protein sequence:
Gene name : ' CDA14
Unigene number: Hs.26813
Probeset Accession ft: N32912
Protein Accession ft: NP_057654
Signal sequence: none found
Transmembrane domains : none found
Cellular Localization: nuclear
31
MRRLNRKKTL SLVKELDAFP KVPESYVETS ASGGTVSLIA FTTMALLTIM EFSVYQDTWM 60
KYEYEVDKDF SSKLRINIDI TVAMKCQYVG ADVLDLAETM VASADGLVYE PTVFDLSPQQ 120
KEWQRMLQLI QSRLQEEHSL QDVIFKSAFK STSTALPPRE DDSSQSPNAC RIHGHLYVNK 180
VAGNFHITVG KAIPHPRGHA HLAALVNHES YNFSHRIDHL SFGELVPAII NPLDGTEKIA 240
IDHNQMFQYF ITWPTKLHT YKISADTHQF SVTERERIIN HAAGSHGVSG IFMKYDLSSL 300
MVTVTEEHMP FWQFFVRLCG IVGGIFSTTG MLHGIβKFIV EIICCRFRLG SYKPVNSVPF 360
EDGHTDNHLP LLENNTH
Uterine
A225 DNA SEQUENCE:
Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H.sapiens] Unigene number: Hs.100686 Probeset Accession ft: AA487468 Nucleic Acid Accession ft: AA487468 Coding sequence: 55-555 (underlined sequences correspond to start and stop codons)
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I I I I I
CGGCACCAAG AGCACTGGCC AAGTCAGCTT CTTCTGAGAβ AGTCTCTAGA AGACATGATG 60 CTACACTCAG CTTTGGGTCT CTGCCTCTTA CTCGTCACAG TTTCTTCCAA CCTTGCCATT 120 GCAATAAAAA AGGAAAAGAβ GCCTCCTCAβ ACACTCTCAA GAGGATGβGG AGATβACATC 180 ACTTGGGTAC AAACTTATGA AGAAβGTCTC TTTTATβCTC AAAAAAβTAA βAAβCCATTA 240 ATGGTTATTC ATCACCTGGA GGATTGTCAA TACTCTCAAG CACTAAAGAA AβTATTTβCC 300 CAAAATGAAβ AAATACAAGA AATGGCTCAG AATAAGTTCA TCATGCTAAA CCTTATβCAT 360 GAAACCACTG ATAAGAATTT ATCACCTGAT GGGCAATATG TGCCTAGAAT CATGTTTGTA 420 GACCCTTCTT TAACAGTTAG AGCTGACATA GCTGGAAGAT ACTCTAACAG ATTGTACACA 480 TATGAGCCTC GGGATTTACC CCTATTGATA GAAAACATGA AGAAAGCATT AAGACTTATT 540 CAGTCAGAGC TATAAGAGAT GATAGAAAAA AGCCTTCACT TCAAAGAAGT CAAATTTCAT 600 GAAGAAAACC TCTGGCACAT TGACAAATAC TAAATGTGCA AGTATATAGA TTTTGTAATA 660 TTACTATTTA GTTTTTTTAA TGTGTTTGCA ATAGTCTTAT TAAAATAAAT GTTTTTTAAA 720 TCTβAAAAAA AAAAAAAAAA AAAAAAAAA
A226 Protein εequence: Gene name: ESTs, Weakly similar to JE0350 Anterior gradient-2 [H.sapiens] Unigene number: Hs.100686 Probeset Accession #: AA487468 Protein Accession #: none found Signal sequence : 1-23 Transmembrane domains: none found Cellular Localization: secreted
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I I I I I i •
MMLHSALGLC LLLVTVSSNL AIAIKKEKRP PQTLSRGWβD DITWVQTYEE βLFYAQKSKK 60 PLMVIHHLED CQYSQALKKV FAQNEEIQEM AQNKFIMLNL MHETTDKNLS PDβQYVPRIM 120 FVDPSLTVRA DIAβRYSNRL YTYEPRDLPL LIENMKKALR LIQSEL
A227 DNA SEQUENCE
Gene name: G protein-coupled receptor 49 (GPR49) (HG38) (LGR5)
Unigene number: Hs.285529
Probeset Accession ft: AA460530
Nucleic Acid Accession #: NM_003667
Coding sequence: 201-2924 (underlined sequences correspond to start and stop codons) 1 11 21 31 41 51
I I I I I I
GTGGCGβCAA CCGGCACCTC AGTCCCCGCC GCGCTTCTCC TCGCCGCCCA CGCCGTGGGG 60
TCAGGAACGC GGCGTCTGGC GCTGCAGACG CCCCCTβAGT TGCAGAAGCC CACGGAGCGG 120
CGCCCCGCGC GCCACGGCCC GTAβCAβTCC CβTβCTGCTC TCCGCCCGCG TCCGGCTCGT 180
GGCCCCCTAC TTCGGGCACC ATGGACACCT CCCGGCTCGG TGTGCTCCTG TCCTTGCCTβ 240
TGCTGCTCCA GCTGGCGACC GGGGGCAGCT CTCCCAGGTC TGGTGTGTTG CTGAGGGGCT 300
GCCCCACACA CTGTCATTGC βAGCCCGACG GCAβGATGTT GCTCAGGGTG GACTGCTCCG 360
ACCTGGββCT CTCGGAGCTG CCTTCCAACC TCAGCGTCTT CACCTCCTAC CTAGACCTCA 420
GTATGAACAA CATCAGTCAG CTGCTCCCGA ATCCCCTGCC CAGTCTCCGC TTCCTGGAGβ 480
AGTTACGTCT TGCβGGAAAC GCTCTGACAT ACATTCCCAA GβGAGCATTC ACTGGCCTTT 540
ACAGTCTTAA AGTTCTTATG CTGCAGAATA ATCAGCTAAG ACACGTACCC ACAGAAGCTC 600
TGCAGAATTT GCGAAGCCTT CAATCCCTGC GTCTGGATGC TAACCACATC AGCTATGTGC 660
CCCCAAGCTG TTTCAGTβGC CTGCATTCCC TGAGGCACCT GTGGCTβGAT GACAATGCGT 720
TAACAGAAAT CCCCGTCCAG GCTTTTAGAA βTTTATCGGC ATTβCAAGCC ATGACCTTGG 780
CCCTGAACAA AATACACCAC ATACCAGACT ATGCCTTTGG AAACCTCTCC AβCTTGGTAG 840
TTCTACATCT CCATAACAAT AGAATCCACT CCCTGGGAAA GAAATGCTTT GATGGGCTCC 900
ACAβCCTAβA βACTTTAβAT TTAAATTACA ATAACGTTCA TβAATTCCCC ACTGCAATTA 960
GGACACTCTC CAACCTTAAA GAACTAGGAT TTCATAGCAA CAATATCAGG TCGATACCTG 1020
AGAAAGCATT TGTAββCAAC CCTTCTCTTA TTACAATACA TTTCTATGAC AATCCCATCC 1080
AATTTGTTββ βAβATCTβCT TTTCAACATT TACCTGAACT AAGAACACTG ACTCTGAATG 1140
GTβCCTCACA AATAACTβAA TTTCCTGATT TAACTGGAAC TGCAAACCTG GAGAGTCTGA 1200
CTTTAACTGG AGCACAGATC TCATCTCTTC CTCAAACCGT CTGCAATCAG TTACCTAATC 1260
TCCAAGTGCT AGATCTGTCT TACAACCTAT TAGAAGATTT ACCCAGTTTT TCAβTCTβCC 1320
AAAAGCTTCA GAAAATTGAC CTAAGACATA ATGAAATCTA CGAAATTAAA GTTGACACTT 1380
TCCAGCAGTT GCTTAGCCTC CGATCβCTGA ATTTGGCTTG βAACAAAATT βCTATTATTC 1440
ACCCCAATGC ATTTTCCACT TTGCCATCCC TAATAAAGCT GGACCTATCG TCCAACCTCC 1500
TGTC6TCTTT TCCTATAACT GGGTTACATG GTTTAACTCA CTTAAAATTA ACAGGAAATC 1560
ATGCCTTACA GAGCTTGATA TCATCTGAAA ACTTTCCAβA ACTCAAGGTT ATAβAAATGC 1620
CTTATGCTTA CCAGTGCTGT GCATTTβGAG TGTGTGAGAA TGCCTATAAG ATTTCTAATC 1680
AATGGAATAA AGGTGACAAC AGCAβTATGG ACGACCTTCA TAAGAAAGAT GCTGGAATGT 1740
TTCAGGCTCA AGATGAACGT GACCTTGAAG ATTTCCTGCT TGACTTTGAG GAAGACCTGA 1800
AAGCCCTTCA TTCAβTGCAG TGTTCACCTT CCCCAGβCCC CTTCAAACCC TGTGAACACC 1860
TGCTTGATβG CTGGCTβATC AGAATTGGAG TGTβGACCAT AGCAGTTCTG GCACTTACTT 1920
GTAATβCTTT βGTGACTTCA ACAGTTTTCA GATCCCCTCT GTACATTTCC CCCATTAAAC 1980
TGTTAATTGG GGTCATCGCA GCAGTGAACA TGCTCACGGG AGTCTCCAGT βCCGTGCTGG 2040
CTGGTGTGGA TGCGTTCACT TTTGGCAGCT TTGCACGACA TGGTGCCTGG TGGGAGAATG 2100
GββTTGGTTβ CCATGTCATT GGTTTTTTGT CCATTTTTGC TTCAGAATCA TCTGTTTTCC 2160
TGCTTACTCT GGCAβCCCTβ GAGCGTGGGT TCTCTGTGAA ATATTCTGCA AAATTTGAAA 2220
CGAAAGCTCC ATTTTCTAGC CTβAAAGTAA TCATTTTGCT CTGTGCCCTβ CTββCCTTβA 2280
CCATGGCCGC AGTTCCCCTG CTGββTβGCA GCAAGTATGG CGCCTCCCCT CTCTGCCTβC 2340
CTTTβCCTTT TGGGGAβCCC ACCACCATGG GCTACATGGT CGCTCTCATC TTGCTCAATT 2400
CCCTTTGCTT CCTCATβATG ACCATTGCCT ACACCAAGCT CTACTβCAAT TTββACAAβG 2460
GAβACCTGGA GAATATTTGG βACTGCTCTA TGGTAAAACA CATTGCCCTβ TTβCTCTTCA 2520
CCAACTGCAT CCTAAACTGC CCTGTGβCTT TCTTGTCCTT CTCCTCTTTA ATAAACCTTA 2580
CATTTATCAG TCCTGAAGTA ATTAAβTTTA TCCTTCTGGT ββTAβTCCCA CTTCCTβCAT 2640
GTCTCAATCC CCTTCTCTAC ATCTTGTTCA ATCCTCACTT TAAGGAβGAT CTGGTGAGCC 2700
TGAGAAAGCA AACCTACGTC TβGACAAGAT CAAAACACCC AAGCTTGATG TCAATTAACT 2760
CTGATGATGT CGAAAAACAβ TCCTGTGACT CAACTCAAGC CTTββTAACC TTTACCAGCT 2820
CCAGCATCAC TTATGACCTG CCTCCCAGTT CCGTGCCATC ACCAGCTTAT CCAβTβACTC 2880
AGAGCTGCCA TCTTTCCTCT GTGGCATTTβ TCCCATβTCT CTAATTAATA TβTGAAGGAA 2940
AATGTTTTCA AAGGTTGAGA ACCTGAAAAT GTGAGATTGA βTATATCAβA GCAGTAATTA 3000
ATAAGAAGAβ CTβAGGTGAA ACTCGGTTTA AA
A228 Protein sequence Gene name: G protein-coupled receptor 49 (GPR49) (HG38) (LGR5) Unigene number: Hs.285529 Protein Accession #: NP_003658.1 Signal sequence: 1-22 Transmembrane domains : 557-579, 596-618, 641-663, 687-709, 724-746, 770-792, 803-825 Cellular Localization: plasma membrane
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I
MDTSRLGVLL S ILPVLLQLAT G IGSSPRSGVL LRGCPTHCHC E IPDGRMLLRV D ICSDLGLSEL 60 PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALT IPKGAF TGLYSLKVLM 120 LQNNQLRHVP TEALQNLRSL QSLRLDANHI SYVPPSCFSβ LHSLRHLWLD DNALTEIPVQ 180 AFRSLSALQA MTLALNKIHH IPDYAFGNLS SLWLHLHNN RIHSLGKKCF DGLHSLETLD 240 LNYNNLDEFP TAIRTLSNLK ELGFHSNNIR SIPEKAFVβN PSLITIHFYD NPIQFVGRSA 300 FQHLPELRTL TLNGASQITE FPDLTGTANL ESLTLTβAQI SSLPQTVCNQ LPNLQVLDLS 360 YNLLEDLPSF SVCQKLQKID LRHNEIYEIK VDTFQQLLSL RSLNLAWNKI AIIHPNAFST 420 LPSLIKLDLS SNLLSSFPIT GLHGLTHLKL TGNHALQSLI SSENFPELKV IEMPYAYQCC 480 AFGVCENAYK ISNQWNKGDN SSMDDLHKKD AGMFQAQDER DLEDFLLDFE EDLKALHSVQ 540 CSPSPGPFKP CEHLLDGWLI RIGVWTIAVL ALTCNALVTS TVFRSPLYIS PIKLLIGVIA 600 AVNMLTGVSS AVLAGVDAFT FGSFARHGAW WENGVGCHVI GFLSIFASES SVFLLTLAAL 660 ERβFSVKYSA KFETKAPFSS LKVIILLCAL LALTMAAVPL LGGSKYGASP LCLPLPFGEP 720 STMβYMVALI LLNSLCFLMM TIAYTKLYCN LDKGDLENIW DCSMVKHIAL LLFTNCILNC 780 PVAFLSFSSL INLTFISPEV IKFILLVWP LPACLNPLLY ILFNPHFKED LVSLRKQTYV 840 WTRSKHPSLM SINSDDVEKQ SCDSTQALVT FTSSSITYDL PPSSVPSPAY PVTESCHLSS 900 VAFVPCL
Table 75: See Table 1 Table 76A depicts Seq ID No, UnigenelD, UnigeneTiUe, PKey, Predicted Cellular Localization, and Exemplar Accession for each of the sequences in Table 78 The information in Table 76A is linked by SeqlD No to Table 78
Seq ID No Sequence ID No for sequences ir i table
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unit jene gene title
Pred Subcell Loc Predicted sub-cellular localizatior
Seq ID No Pkey ExAccn UnigenelD Unigene Title Pred Subcell Loc
Seq ID 1 & 2 425023 A 956889 Hs 154210 endothelial differentiation, sphingolipi plasma membrane
Seq lD 3.4 424503 NM 002205 Hs 149609 integπn, alpha 5 (fibronectin receptor, plasma membrane
Seq lD 5 & 6 429423 AI016712 Hs 287797 integnn, beta 1 (fibronectin receptor, plasma membrane
Seq lD 7 & 8 400289 X07820 Hs 2258 matnx metalloprotemase 10 (stromelysin secreted
Seq ID 9 & 10 419172 AW338625 Hs 22120 ESTs, similar to TRANSMEMBRANE 4 SUPERF plasma membrane
Seq ID 11 & 12 418007 M13509 Hs 83169 matnx metalloprotemase 1 (interstitial secreted
Seq ID 13 & 14 418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial secreted
Seq ID 15 & 16 407836 T79340 Hs 200272 B-cell CLL lymphoma 6, member B, zinc fi intracell
Seq ID 17. 18 414577 AI056548 Hs72116 hypothetical protein FU20992 similar to secreted
Seq ID 19 & 20 418738 AW388633 Hs 6682 solute earner family 7, (cationic ammo plasma membrane
Seq ID 21 & 22 428368 BE440042 Hs 83326 matnx metalloproteinase 3 (stromelysin secreted
Seq ID 23 & 24 415138 C18356 Hs 295944 tissue factor pathway inhibitor 2 secreted
Seq ID 25 & 26 429276 AF056085 Hs 198612 G protein-coupled receptor 51 plasma membrane
Seq ID 27 & 28 418994 AA296520 Hs 89546 selectin E (endothelial adhesion molecul plasma membrane
Seq ID 29 & 30 407975 X89426 Hs 41716 endothelial cell specific molecule 1 secreted
Seq ID 31 & 32 429113 D28235 Hs 196384 prostaglaπdm endoperoxide synthase 2 (p intracell
Seq lD 33& 34 418506 AA084248 Hs 85339 G protein-coupled receptor 39 plasma membrane
Seq ID 35.36 423961 D13666 Hs 136348 penostin (OSF-2os) secreted
Seq ID 37 & 38 414812 X72755 Hs 77367 monokine induced by gamma interferon secreted
Seq ID 39 & 40 417433 BE270266 Hs 82128 5T4 oncofetal trophoblast glycoprotein plasma membrane
Seq ID 41 & 42 417433 BE270266 Hs 82128 5T4 oncofetal trophoblast glycoprotein plasma membrane
Seq lD43&44 424399 AI905687 AI905687 IL-BT095-190199019 BT095 Homo secreted
Seq ID 45 & 46 422867 L32137 Hs 1584 cartilage oligomeπc matnx protein (pse secreted
Seq lD 47 & 48 428227 AA321649 Hs 2248 small inducible cytokine subfamily B (Cy secreted
Seq ID 49.50 444381 BE387335 Hs 283713 ESTs, Weakly similar to S64054 hypotheti secreted
Seq ID 51 & 52 439569 AW602166 Hs 222399 CEGP1 protein secreted
Seq ID 538.54 411558 AA102670 Hs 70725 gamma-aminobutyπc acid (GABA) A recepto plasma membrane
Seq ID 55 & 56 400303 AA242758 Hs 79136 UV-1 protein, estrogen regulated plasma membrane
Seq ID 57 & 58 411789 AF245505 Hs 72157 Adlican secreted
Seq ID 59 & 60 428698 AA852773 Hs 334838 KIAA1866 protein plasma membrane
Seq ID 61 & 62 450098 W27249 Hs 8109 hypothetical protein FLJ21080 intracell
Seq ID 63 & 64 421552 AF026692 Hs 105700 secreted fnzzled-related protein 4 secreted
Seq ID 65 & 66 452747 BE153855 Hs 61460 Ig superfamily receptor LNIR plasma membrane
Seq ID 67 & 68 415539 AI733881 Hs 72472 BMP-R1B plasma membrane
Seq ID 698, 70 416636 N32536 Hs 42645 solute camerfamily 16 (monocarboxylic plasma membrane
Seq ID 71 8, 72 416636 N32536 Hs 42645 solute camerfamily 16 (monocarboxylic plasma membrane
Seq ID 73 & 74 409079 W87707 Hs 82065 interleukin 6 signal transducer (gp130, plasma membrane
Seq ID 75 & 76 442082 R41823 Hs 7413 ESTs plasma membrane
Seq ID 77.78 400297 AI127076 Hs 306201 hypothetical protein DKFZp56401278 plasma membrane
Seq ID 79 & 80 451398 AI793124 Hs 144479 ESTs intracell
Seq ID 81 8, 82 429220 AW207206 ESTs plasma membrane
Seq ID 83 & 84 421524 AA312082 Hs 105445 GDNF family receptor alpha 1 plasma membrane
Seq ID 85 & 86 423242 AL039402 Hs 125783 DEME-6 protein plasma membrane
Seq ID 87.88 423242 AL039402 Hs 125783 DEME-6 protein intracell
Seq ID 89 & 90 423242 AL039402 Hs 125783 DEME-6 protein intracell
Seq ID 91 & 92 452190 H26735 Hs 91668 Homo sapiens clone PP1498 unknown mRNA intracell
Seq ID 93 & 94 452190 H26735 Hs 91668 Homo sapiens clone PP1498 unknown mRNA intracell
Seq ID 95.96 325372 Phase 2 & 3 Exons cytoplasmic
Seq ID 97 & 98 450375 AA009647 a disintegnn and metalloprotemase doma plasma membrane
Seq ID 99 & 100 426215 AW963419 Hs 155223 stanπiocalcin 2 secreted
Seq ID 101 & 102 425247 NM 00594C I Hs 155324 matnx metalloprotemase 11 (stromelysin secreted
Seq ID 103 & 104 429353 AL117406 Hs 335891 ATP-bmding cassette transporter MRP8 plasma membrane
Seq ID 1058c 106 429353 AU 17406 Hs 335891 ATP-bmding cassette transporter MRP8 plasma membrane
Seq ID 107 & 108 432201 AI538613 Hs 298241 Transmembrane protease, seπne 3 plasma membrane
Seq ID 109 & 110 427585 D31152 Hs 179729 collagen, type X, alpha 1 (Schmid metaph secreted
Seq lD 111 _ 112 446163 AA026880 Hs 25252 prolactin receptor plasma membrane
Seq ID 113 & 114 442117 AW664964 Hs 128899 ESTs, hypothetical protein for IMAGE 447 plasma membrane
Seq ID 115 & 116 428179 AI127772 Hs 279696 serum/glucocorticoid regulated kinase-li intracell
Seq lD 117 & 118 431211 M86849 Hs 323733 gap junction protein, beta 2, 6kD (conn plasma membrane
Seq ID 119 & 120 447033 AI357412 Hs 157601 ESTs secreted
Seq ID 121 & 122 447033 AI357412 Hs 157601 ESTs secreted
Seq ID 1238, 124 447033 AI357412 Hs 157601 ESTs secreted
Seq ID 1258, 126 115522 BE614387 Hs 333893 c-Myc target JP01 intracell
Seq ID 1278, 128 452679 Z42387 Hs 83883 transmembrane, prostate androgen induced plasma membrane
Seq ID 129 & 130 446051 BE048061 Hs 37054 ephπn A3 plasma membrane
Seq ID 131 & 132 422048 NM.012445 Hs 288126 spondm 2, extracellular matnx protein secreted
Seq ID 133 & 134 410418 D31382 Hs 63325 transmembrane protease, seπne 4 plasma membrane
Seq ID 135 & 136 446342 BE298665 Hs 14846 Homo sapiens mRNA, cDNA DKFZp564D016 (fr plasma membrane
Seq ID 137 & 138 422260 AA315993 Hs 105484 regenerating gene type IV secreted Seq ID 1398, 140 409041 AB033025 Hs 50081 Hypothetical protein XP.051860 (KIAA119 secreted
Seq ID 141 & 142 409041 AB033025 Hs 50081 Hypothetical protein XP.051860 (KIAA119 secreted
Seq ID 1438, 144 111929 AF027208 Hs 112360 prominin (mouse) like 1 plasma membrane
Seq ID 1458, 146 111929 AF027208 Hs 112360 prominin (mouse) like 1 plasma membrane
Seq ID 147 & 148 111929 AF027208 Hs 112360 prominin (mouse) like 1 plasma membrane
Seq ID 1498, 150 104888 AW939591 Hs 5940 mucin 13 epithelial transmembrane plasma membrane
Seq ID 151 & 152 420159 AI572490 Hs 99785 Homo sapiens cDNA FLJ21245 fis clone C plasma membrane
Seq ID 153 .154 422330 D30783 Hs 115263 epiregul plasma membrane
Seq ID 155 & 156 452461 N78223 Hs 108106 transcnption factor intracell
Seq ID 1578, 158 413324 V00571 Hs 75294 corticotropin releasing hormone secreted
Seq ID 159 & 160 412420 AL035668 Hs 73853 bone morphogenetic protein 2 secreted
Seq ID 161 & 162 416658 U03272 Hs 79432 fibπllm 2 (congenital contractural ara secreted
Seq ID 163 & 164 407811 AW190902 Hs 40098 cysteine knot superfamily 1 BMP antagoπ secreted
Seq ID 165 402230 Fgeπesh predicted CYTOCHROME P4504F5 ( intracell
Seq ID 166 & 167 402230 Fgenesh predicted CYTOCHROME P4504F5 ( intracell
Seq ID 168 & 169 432829 W60377 Hs 57772 ESTs intracell
Seq ID 170 _ 171 425721 AC002115 Hs 159309 uroplakin 1A plasma membrane
Seq ID 1728, 173 420370 Y13645 Hs 97234 uroplakin 2 plasma membrane
Seq ID 1748, 175 437852 BE001836 Hs 256897 ESTs Weakly similarto dJ365012 1 [H sa plasma membrane
Seq ID 176 & 177 402075 ENSP00000251056* Plasma membrane calcium secreted
Seq ID 178 & 179 421110 AJ250717 Hs 1355 cathepsin E secreted
Seq ID 180 & 181 451668 Z43948 Hs 326444 cartilage acidic protein 1 plasma membrane
Seq ID 182 & 183 451668 Z43948 Hs 326444 cartilage acidic protein 1 secreted
Seq ID 184 & 185 451668 Z43948 Hs 326444 cartilage acidic protein 1 intracell
Seq ID 186 & 187 408243 Y00787 Hs 624 interleukin 8 secreted
Seq ID 188 & 189 422282 AF019225 Hs 114309 apolipoprotein L secreted
Seq ID 190 & 191 425852 AK001504 Hs 159651 death receptor 6 TNF superfamily member plasma membrane
Seq ID 192 & 193 439738 BE246502 Hs 9598 sema domain immunoglobulin domain (Ig) plasma membrane
Seq ID 194 & 195 404875 NM 022819* Homo sapiens phospholipase A2 intracell
Seq ID 1968, 197 425883 AL137708 Hs 161031 Homo sapiens mRNA cDNA DKFZp434K0322 (f plasma membrane
Seq ID 198 & 199 404977 Insulin like growth factor 2 (somatomedi secreted
Seq ID 200 & 201 420876 AA918425 Hs 177744 ESTs plasma membrane
Seq ID 202 & 203 427747 AW411425 Hs 180655 seπne/threomne kinase 12 intracell
Seq ID 204 & 205 420281 AI623693 Hs 323494 Predicted cation efflux pump plasma membrane
Seq ID 206 & 207 446673 NM.016361 Hs 15871 LPAP for lysophosphatidic acid phosphata intracell
Seq ID 208 437553 AI829935 Hs 130497 ESTs Weakly similar to MAT8 HUMAN CHLOR plasma membrane
Seq ID 209 & 210 437553 AI829935 Hs 130497 ESTs, Weakly similar to MAT8 HUMAN CHLOR plasma membrane
Seq ID 211 8, 212 437553 AI829935 Hs 130497 ESTs Weakly similar to MAT8 HUMAN CHLOR plasma membrane
Seq ID 213 & 214 426900 AW163564 Hs 142375 ESTs plasma membrane
Seq ID 215 & 216 426900 AW163564 Hs 142375 ESTs plasma membrane
Seq ID 2178, 218 426900 AW163564 Hs 142375 ESTs plasma membrane
Seq ID 219 & 220 405932 C15000305 gι|3806122|gb|AAC69198 1| (AF0 intracell
Seq ID 221 & 222 405932 C15000305 gι|3806122|gb|AAC69198 1| (AF0 intracell
Seq ID 223 & 224 424008 R02740 Hs 137555 putative chemokine receptor; GTP binding plasma membrane
Seq ID 225 & 226 424008 R02740 Hs 137555 putative chemokine receptor; GTP binding plasma membrane
Seq ID 227 & 228 424008 R02740 Hs 137555 putative chemokine receptor; GTP-bindmg plasma membrane
Seq ID 229 & 230 444342 NM_014398 I Hs 10887 similarto lysosome-assoαated membrane secreted
Seq ID 231 & 232 421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy secreted
Seq ID 233 & 234 417079 U65590 Hs 81134 interieukin 1 receptor antagonist secreted
Seq ID 235 & 236 412986 X81120 Hs 75110 cannabinoid receptor 1 (brain) plasma membrane
Seq ID 237 & 238 412986 X81120 Hs 75110 cannab oid receptor 1 (brain) plasma membrane
Seq ID 239 & 240 412986 X81120 Hs 75110 cannabinoid receptor 1 (brain) plasma membrane
Seq ID 241 & 242 447072 D61594 Hs 17279 tyrosylprotein sulfotransferase 1 intracell
Seq ID 243 & 244 419723 AL120193 Hs 339810 longevity assurance (LAG1. S cerevisiae secreted
Seq ID 245 & 246 419723 AL120193 Hs 339810 longevity assurance (LAG1. S cerevisiae plasma membrane
Seq ID 247 & 248 430890 X54232 Hs 2699 glypicaπ 1 plasma membrane
Seq ID 249 & 250 456759 BE259150 Hs 127792 delta (Drosophila) like 3 plasma membrane
Seq ID 251 429466 M85835 Hs 12827 ESTs
Seq ID 252 429466 M85835 Hs 12827 ESTs
Seq ID 2538, 254 419721 NM.001650 Hs 288650 aquaponn 4 plasma membrane
Seq ID 255 & 256 407034 U84540 gb Human dystrobrevin isoform DTN 3 (DTN secreted
Seq ID 257 & 258 413472 BE242870 Hs 75379 solute earner family 1 (glial high affi plasma membrane
Seq ID 259 & 260 438380 T06430 Hs 6194 chondroitin sulfate proteoglycan BEHAB/b secreted 8, plasma membrane
Seq ID 261 & 262 426271 AF026547 Hs 169047 chondroitin sulfate proteoglycan 3 (neur secreted
Seq ID 263 & 264 419704 AA429104 Hs 45057 ESTs intracell
Seq ID 2658, 266 444471 AB020684 Hs 11217 KIAA0877 protein plasma membrane
Seq ID 267 & 268 409395 U46745 Hs 336678 dystrobrevin, alpha secreted
Seq ID 269 & 270 413063 AL035737 Hs 75184 chitmase 3-lιke 1 (cartilage glycoprote secreted
Seq ID 271 & 272 433800 AI034361 Hs 135150 lung type-l cell membrane-associated gly plasma membrane
Seq ID 273 458435 AI418718 Hs 144121 ESTs Weakly similar to T46916 hypotheti
Seq ID 274 458435 AI418718 Hs 144121 ESTs Weakly similarto T46916 hypotheti
Seq ID 275 & 276 424343 AW956360 Hs 4748 adenylate cyclase activating polypeptide plasma membrane
Seq ID 277 & 278 424998 U58515 Hs 154138 chitmase 3-lιke 2 secreted
Seq ID 279 & 280 412709 AL022327 Hs 74518 KIAA0027 protein plasma membrane
Seq ID 281 & 282 435615 Y15065 Hs 4975 potassium voltage-gated channel KQT lik plasma membrane
Seq ID 283 & 284 404049 NM.018937* Homo sapiens protocadhenn be plasma membrane
Seq ID 285 & 286 418932 L34059 Hs 89484 cadhenn 4 type 1, R-cadheπn (retinal) plasma membrane
Seq ID 287 & 288 404029 NM_018936* Homo sapiens protocadhenn be plasma membrane
Seq ID 289 & 290 436480 AJ271643 Hs 87469 putative acid sensing ion channel intracell
Seq ID 291 8, 292 452401 NM 007115 Hs 29352 turner necrosis factor alpha-induced pro secreted
Seq ID 293 & 294 452401 NM 007115 Hs 29352 tumor necrosis factor alpha-induced pro secreted
Seq ID 2958, 296 436895 AF037335 Hs 5338 carbonic anhydrase XII plasma membrane
Seq ID 297 & 298 421471 U90545 Hs 327179 solute earner family 17 (sodium phospha plasma membrane Seq ID 299 & 300 428296 NM 003058 Hs 183572 solute camerfamily 22 (organic cation plasma membrane
Seq ID 301 8, 302 423508 AW604297 Hs 129711 hepatitis A virus cellular receptor 1 plasma membrane
Seq ID 303 & 304 450001 NM 001044 Hs 406 solute camerfamily 6 (neurotransmitte plasma membrane
Seq ID 305 & 306 410407 X66~839 Hs 63287 carbonic anhydrase IX plasma membrane
Seq ID 307 & 308 453496 AA442103 Hs 33084 solute camerfamily 2 (facilitated glu plasma membrane
Seq ID 309 & 310 420737 L08096 Hs 99899 CD70 , tumor necrosis factor (ligand) s plasma membrane
Seq ID 311 8, 312 309931 AW341683 gb hd13d01 x1 Soares_NFL_T_GBC_S1 Homo s plasma membrane
Seq ID 3138, 314 412719 AW016610 Hs 816 ESTs intracell
Seq ID 315 & 316 417034 NM 006183 Hs 80962 neurotensin secreted
Seq ID 317 & 318 430486 BE062109 Hs 241551 chloπde channel, calcium activated, fam plasma membrane
Seq ID 319 & 320 413753 U17760 Hs 75517 laminin, beta 3 (nicein (125kD), kalinm secreted
Seq ID 321 & 322 425650 NM 001944 Hs 1925 desmoglein 3 (pemphigus vulgans antigen plasma membrane
Seq ID 323 & 324 423673 BE003054 Hs 1695 matrix metalloproteinase 12 (macrophage secreted
Seq ID 325 & 326 418663 AK001100 Hs 41690 desmocollm 3 plasma membrane
Seq ID 327 & 328 418663 AK001100 Hs 41690 desmocollm 3 plasma membrane
Seq ID 329 & 330 429610 AB024937 Hs 211092 LUNX protein, PLUNC (palate lung and nas secreted
Seq ID 331 & 332 406690 M29540 Hs 220529 carcmoembryonie antigen related cell ad plasma membrane
Seq ID 333 & 334 431846 BE019924 Hs 271580 uroplakin 1B plasma membrane
Seq ID 335 & 336 422158 L10343 Hs 112341 protease inhibitor 3, skm-deπved (SKAL secreted
Seq ID 337 & 338 431958 X63629 Hs 2877 cadhenn 3, type 1, P-cadheπn (placenta plasma membrane
Seq ID 339 & 340 437044 AL035864 Hs 69517 differentially expressed in Fanconis an plasma membrane
Seq ID 341 & 342 428484 AF104032 Hs 184601 solute earner family 7 (cationic ammo plasma membrane
Seq ID 3438, 344 429211 AF052693 Hs 198249 gap junction protein, beta 5 (connexm 3 plasma membrane
Seq ID 345 & 346 417389 BE260964 Hs 82045 midkme (neuπte growth-promoting fxtor secreted
Seq ID 347 & 348 431009 BE149762 Hs 48956 gap junction protein, beta 6 (connexm 3 plasma membrane
Seq ID 349 & 350 417542 J04129 Hs 82269 progestageπ-associated eπdometπal prote secreted
Seq ID 351 & 352 449230 BE613348 Hs 211579 melanoma cell adhesion molecule plasma membrane
Seq ID 3538, 354 410555 U92649 Hs 64311 a disintegnn and metalloprotemase doma plasma membrane
Seq ID 355 & 356 410555 U92649 Hs 64311 a disintegnn and metalloprotemase doma plasma membrane
Seq ID 357 & 358 424687 J05070 Hs 151738 matnx metalloprotemase 9 (gelatmase B secreted
Seq ID 359 & 360 418462 BE001596 Hs 85266 integnn, beta 4 plasma membrane
Seq ID 361 & 362 410274 AA381807 Hs 61762 hypoxia-inducible protein 2 secreted
Seq ID 3638, 364 439606 W79123 Hs 58561 G protein-coupled receptor 87 plasma membrane
Seq ID 3658, 366 404877 NM.005365 Homo sapiens melanoma antigen, intracell
Seq ID 367 & 368 444781 NM 014400 Hs 11950 GPI-anchored metastasis-associated prote plasma membrane
Seq ID 369 & 370 109424 NM 005329 Hs 85962 hyaluronan synthase 3 plasma membrane
Seq ID 371 & 372 415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t plasma membrane
Seq ID 373 & 374 415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t plasma membrane
Seq ID 375 & 376 415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t plasma membrane
Seq ID 377 & 378 415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t plasma membrane
Seq ID 379 & 380 415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t plasma membrane
Seq ID 381 & 382 415817 U88967 Hs 78867 protein tyrosine phosphatase, receptor-t plasma membrane
Seq ID 383 & 384 421817 AF146074 Hs 108660 ATP binding cassette, sub-family C (CFTR plasma membrane
Seq ID 385 & 386 418678 NM.001327 Hs 87225 cancer/testis antigen (NY-ESO-1) intracell
Seq ID 387 & 388 418678 NM 001327 Hs 87225 caπcer/testis antigen (NY-ESO-1) intracell
Seq ID 389 _ 390 409420 Z15008 Hs 54451 laminin, gamma 2 (nicem (100kD), kalim secreted
Seq ID 391 & 392 332180 AF134160 Hs 7327 claudin 1 plasma membrane
Seq ID 393 & 394 408790 AW580227 Hs 47860 neurotrophic tyrosine kinase, receptor, plasma membrane
Seq ID 395 & 396 408790 AW580227 Hs 47860 neurotrophic tyrosine kinase, receptor, plasma membrane
Seq ID 397 & 398 439223 AW238299 Hs 250618 UL16 binding protein 2 plasma membrane
Seq ID 399 & 400 409757 NM 001898 Hs 123114 cystatin SN secreted
Seq ID 401 & 402 428969 AF120274 Hs 194689 artemin secreted
Seq ID 403 & 404 428969 AF120274 Hs 194689 artemin secreted
Seq ID 4058, 406 428969 AF120274 Hs 194689 artemin secreted
Seq ID 407 & 408 428969 AF120274 Hs 194689 artemin secreted
Seq ID 4098, 410 450701 H39960 Hs 288467 hypothetical protein XP.098151 (leuciπe- secreted
Seq ID 411 8, 412 450701 H39960 Hs 288467 hypothetical protein XP_098151 (leucine- secreted
Seq ID 413 & 414 414774 X02419 Hs 77274 plasmmogen activator, urokmase secreted
Seq 104158,416 407944 R34008 Hs 239727 desmocollm 2 plasma membrane
Seq ID 417 & 418 407944 R34008 Hs 239727 desmocollm 2 plasma membrane
Seq ID 419 & 420 428486 AW583497 Hs 184604 pancreatic polypeptide secreted
Seq ID 421 & 422 457489 AI693815 Hs 127179 cryptic gene secreted
Seq ID 423 & 424 432874 W94322 Hs 279651 melanoma inhibitory activity secreted
Seq ID 425 & 426 445891 AW391342 Hs 199460 DPCR1 protein plasma membrane
Seq ID 427 & 428 445891 AW391342 Hs 199460 DPCR1 protein plasma membrane
Seq ID 4298, 430 404682 C9001188*gι|12738842|reflNP 073725 1| p secreted
Seq ID 431 & 432 429547 AW009166 Hs 99376 ESTs secreted
Seq ID 433 & 434 425921 NM_00723' I Hs 162211 solute earner family 6 (neurotransmitte plasma membrane
Seq ID 4358,436 407242 M18728 gb Human nonspecific crossreacting antig plasma membrane
Seq ID 437 & 438 407242 M18728 gb Human nonspecific crossreacting antig plasma membrane
Seq ID 439 & 440 407242 M18728 gb Human nonspecific crossreacting antig plasma membrane
Seq ID 441 8, 442 432596 AJ224741 Hs 278461 matnlin 3 secreted
Seq ID 443 & 444 444006 BE395085 Hs 10086 type I transmembrane protein Fn14 plasma membrane
Seq ID 445 & 446 423685 BE350494 Hs 49753 uveal autoantigen with coiled coil domai intracell
Seq ID 447 & 448 428392 H10233 Hs 2265 secretory granule, neuroeπdocπne protei secreted
Seq ID 449 & 450 429597 NM 003816 Hs 2442 a disintegnn and metalloproteinase doma plasma membrane
Seq ID 451 & 452 448030 N30714 Hs 325960 membrane-spanning 4-domaιns, subfamily A plasma membrane
Seq ID 453 & 454 422109 S73265 Hs 1473 gastπn releasing peptide secreted
Seq ID 455 & 456 419235 AW470411 Hs 288433 neurotπmin plasma membrane
Seq ID 4578, 458 449048 Z45051 Hs 22920 similarto S68401 (cattle) glucose indue plasma membrane
Seq ID 459 & 460 427333 AF067797 Hs 176658 aquapoπn 8 plasma membrane
Seq ID 461 & 462 417931 W95642 Hs 82961 trefoil factor 3 (intestinal) secreted
Seq ID 463 & 464 419216 AU076718 Hs 164021 small inducible cytokine subfamily B (Cy secreted Seq ID 465 & 466 431629 AU077025 Hs 265827 interferon, alpha-inducible protein (clo secreted
Seq ID 4678, 468 413554 AA319146 Hs 75426 secretogranin II (chromogranm C) secreted
Seq ID 4698, 470 452194 AI694413 Hs 332649 Ubiquitin like protein FAT10?" plasma membrane
Seq ID 471 & 472 452194 AI694413 Hs 332649 Ubiquitin like protein FAT10""? plasma membrane
Seq ID 473 & 474 426322 J05068 Hs 2012 traπscobalamtn 1 (vitamin B12 binding pr secreted
Seq ID 475 8, 476 429010 Y18198 Hs 194725 one cut domain, family member 2 intracell
Seq ID 477 & 478 431462 AW583672 Hs 256311 graniπ like neuroeπdocπne peptide precu secreted
Seq ID 4798, 480 448243 AW369771 Hs 52620 integπn, beta 8 plasma membrane
Seq ID 481 & 482 426427 M86699 Hs 169840 TTK protein kinase intracell
Seq ID 4838, 484 428187 AI687303 Hs 285529 G protein-coupled receptor 49 plasma membrane
Seq ID 485 & 486 428579 NM 005756 Hs 184942 G protein-coupled receptor 64 plasma membrane
Seq ID 487 & 488 428579 NM 005756 Hs 184942 G protein-coupled receptor 64 plasma membrane
Seq ID 489 & 490 428579 NM 005756 Hs 184942 G protein-coupled receptor 64 plasma membrane
Seq ID 491 8, 492 428579 NM 005756 Hs 184942 G protein-coupled receptor 64 plasma membrane
Seq ID 493 & 494 445537 AJ245671 Hs 12844 EGF-like-domam multiple 6 secreted
Seq ID 495 & 496 422278 AF072873 Hs 114218 fnzzled (Drosophila) homolog 6 plasma membrane
Seq ID 497 & 498 424620 AA101043 Hs 151254 kallikrein 7 (chymotryptic stratum com secreted
Seq ID 499 & 500 406400 kallikrein 8 (neuropsiπ/ovasin) (KLK8) secreted
Seq ID 501 & 502 431130 NM.006103 Hs 2719 HE4, epididymis specific, whey-acidic pr secreted
Seq ID 503 & 504 420440 NM 002407 Hs 97644 mammaglob 2 secreted
Seq ID 505 & 506 428450 NM 014791 Hs 184339 KIAA0175 gene product intracell
Seq ID 507 & 508 446619 AU076643 Hs 313 secreted phosphoprotein 1 (osteopoπtin, secreted
Seq ID 509 & 510 436982 AB018305 Hs 5378 spondin 1, (f spondm) extracellular mat secreted
Seq ID 511 8, 512 453392 U23752 Hs 32964 SRY (sex determining region Y) box 11 intracell
Seq ID 513 431989 AW972870 Hs 291069 ESTs
Seq ID 514 439820 AL360204 Hs 283853 Homo sapiens mRNA full length insert cDN
Seq ID 515 & 516 409178 BE393948 Hs 50915 kallikrein 5 secreted
Seq ID 517 & 518 426514 BE616633 Hs 170195 bone morphogenetic protein 7 (osteogenic secreted
Seq ID 519 & 520 421478 AI683243 Hs 97258 ESTs, Moderately similar to S29539 πbos plasma membrane
Seq ID 521 & 522 421478 AI683243 Hs 97258 ESTs, Moderately similar to S29539 nbos plasma membrane
Seq ID 523 & 524 425776 U25128 Hs 159499 parathyroid hormone receptor 2 plasma membrane
Seq ID 525 & 526 425776 U25128 Hs 159499 parathyroid hormone receptor 2 plasma membrane
Seq ID 5278, 528 452097 AB002364 Hs 27916 a disintegnn like and metalloprotease ( secreted
Seq ID 529 & 530 416530 U62801 Hs 79361 kallikrein 6 (neurosin zyme) secreted
Seq ID 531 & 532 431515 NM 012152 Hs 258583 endothelial differentiation lysophospha plasma membrane
Seq ID 533 & 534 419452 U33635 Hs 90572 PTK7 protein tyrosine kinase 7 plasma membrane
Seq ID 535 & 536 412078 X69699 Hs 73149 paired box gene 8 intracell
Seq ID 537 & 538 412078 X69699 Hs 73149 paired box gene 8 intracell
Seq ID 539 & 540 411773 NM 006799 Hs 72026 protease, senne, 21 (testisin) secreted
Seq ID 541 & 542 407792 AI077715 Hs 39384 putative secreted ligand homologous to f secreted
Seq ID 543 & 544 431616 AA508552 Hs 195839 ESTs, Weakly similarto I38022 hypotheti plasma membrane
Seq ID 545 & 546 452792 AB037765 Hs 30652 KIAA1344 protein plasma membrane
Seq ID 547 & 548 400294 N95796 Hs 278695 Homo sapiens prostem mRNA, complete eds plasma membrane
Seq ID 549 & 550 432653 N62096 Hs 293185 ESTs, Weakly similar to JC7328 ammo aa plasma membrane
Seq ID 551 & 552 432653 N62096 Hs 293185 ESTs, Weakly similar to JC7328 ammo a plasma membrane
Seq ID 553 & 554 432653 N62096 Hs 293185 ESTs, Weakly similar to JC7328 ammo aci plasma membrane
Seq ID 555 & 556 432653 N62096 Hs 293185 ESTs, Weakly similar to JC7328 ammo aci plasma membrane
Seq ID 557 & 558 400290 H18836 Hs 31608 hypothetical protein FU20041 plasma membrane
Seq ID 559 & 560 410001 AB041036 Hs 57771 kallikrein 11 secreted
Seq ID 561 8, 562 418396 AI765805 Hs 26691 ESTs plasma membrane
Seq ID 5638564 451027 AW519204 Hs 40808 ESTs plasma membrane
Seq ID 565 .566 446057 AI420227 Hs 149358 ESTs, Weakly similar to A46010 X-lmked plasma membrane
Seq ID 567 & 568 433466 AA508353 Hs 105314 relaxm 1 (H1) secreted
Seq ID 569 & 570 453370 AI470523 Hs 139336 ATP-bindmg cassette, sub-family C (CFTR plasma membrane
Seq ID 571 8572 453370 AI470523 Hs 139336 ATP binding cassette, sub-family C (CFTR plasma membrane
Seq ID 573 & 574 414569 AF109298 Hs 118258 prostate cancer associated protein 1 plasma membrane
Seq ID 575 & 576 413435 X51405 Hs 75360 carboxypeptidase E secreted
Seq ID 577 & 578 426501 AW043782 Hs 293616 ESTs plasma membrane
Seq ID 579 & 580 448999 AF179274 Hs 22791 transmembrane protein with EGF-like and plasma membrane
Seq ID 581 & 582 408369 R38438 Hs 182575 solute camerfamily 15 (H??? transport plasma membrane
Seq ID 583 & 584 412628 AI972402 Hs 306051 hypothetical protein MGC2648 secreted
Seq ID 5858, 586 403047 NM.005656* Homo sapiens transmembrane pr plasma membrane
Seq ID 587 & 588 403047 NM.005656* Homo sapiens transmembrane pr plasma membrane
Seq ID 5898590 408430 S79876 Hs 44926 dipeptidylpeptidase IV (CD26, adenosme plasma membrane
Seq ID 591 8,592 445413 AA151342 Hs 12677 CGI-147 protein secreted
Seq ID 593 & 594 451982 F13036 Hs 27373 Homo sapiens mRNA, cDNA DKFZp56401763 (f intracell
Seq ID 5958596 427958 AA418000 Hs 98280 potassium intermediate/small conductance plasma membrane
Seq ID 597 & 598 421887 AW161450 Hs 109201 CGI 86 protein plasma membrane
Seq ID 599 & 600 425071 NM 013989 Hs 154424 deiodmase, lodothyronme, type II secreted
Seq ID 601 & 602 432101 AI918950 Hs 123642 EphA3 plasma membrane
Seq ID 603 & 604 407786 AA687538 Hs 38972 tetraspan 1 plasma membrane
Seq ID 605 & 606 416836 D54745 Hs 80247 cholecystokinin secreted
Seq ID 607 & 608 416539 Y07909 Hs 79368 epithelial membrane protein 1 plasma membrane
Seq ID 609 & 610 131083 Y09763 Hs 22785 gamma-aminobutyπc acid (GABA) A recepto plasma membrane
Seq ID 611 8, 612 131083 Y09763 Hs 22785 gamma-amiπobulyπc acid (GABA) A recepto plasma membrane
Seq ID 613 & 614 131083 Y09763 Hs 22785 gamma-aminobutyπc acid (GABA) A recepto plasma membrane
Seq ID 615 & 616 131083 Y09763 Hs 22785 gamma-aminobutyπc acid (GABA) A recepto plasma membrane
Seq ID 617 & 618 422424 AI186431 Hs 296638 prostate differentiation factor secreted
Seq ID 619 & 620 428970 BE276891 Hs 194691 retinoic acid induced 3 plasma membrane
Seq ID 621 & 622 428330 L22524 Hs 2256 matnx metalloprotemase 7 (matπlysin secreted
Seq ID 6238624 439018 AW300887 Hs 26638 membrane-spanning 4-domaιns, subfamily A plasma membrane
Seq ID 6258626 420610 AI683183 Hs 99348 distal less homeo box 5 intracell
Seq ID 627 & 628 425723 NM 014420 Hs 159311 diekkopf (Xenopus laevis) homolog 4 secreted Seq ID 629 8630 456662 NM 002448 Hs.1494 msh (Drosophila) homeo box homolog 1 (fo intracell
Seq tD 631 & 632 418281 U09550 Hs.1154 oviductal glycoprotein 1, 120kD (mucin 9 secreted
Seq ID 633 8634 429903 AL134197 Hs.93597 cyclin-depeπdeπt kinase 5, regulatory su intracell
Table 76B:
Pkey: Unique Eos probeset identifier number
CAT number: Gene cluster number
Accession: Genbank accession numbers
Pkey CAT Numbsr Accs^sioπ 424399 238961.1 AI905687 AI905624 AI905837 AI905623 AA340069 R75793 W72837 BE074512 AI905633 W72838 BE092421 AI127172 BE186013 AW070916
AI139456AW176044 AW291950
429220 301384 AW207206 AW341473 AA448195 AI951341 450375 83327.1 AA009647 AA131254 AA374293 AW954405 H04410 AW606284 AA151166 BE157467 BE157601 H04384 W46291 AW663674 H04021 H01532
AA190993 H03231 H59605 H01642 AA852876 AA113758 AA626915 AA746952 AI161014 AA099554 69067
Table 76C:
Pkey: Unique number corresponding to an Eos probeset
Ref: Sequence source. The 7 digit numbers in this column are Genbank Identifier (Gl) numbers. "Dunham I. et al." refers to the publication entitled The DNA sequence of human chromosome 22." Dunham I. et al., Nature (1999) 402:489495. Strand: Indicates DNA strand from which exons were predicted.
NLposition: Indicates nucleotide positions of predicted exons.
Pkey Ref Strand Nt position
402075 8117407 Plus 121907-122035,122804-122921,124019-124161,124455-124610,125672-126076
402230 9966312 Minus 29782-29932
403047 3540153 Minus 59793-59968
404029 7671252 Plus 108716-111112
404049 3688074 Minus 75765-78155
404682 9797231 Minus 40977-41150
404875 9801324 Plus 96588-96732,97722-97831
404877 1519284 Plus 1095-2107
404977 3738341 Minus 43081-43229
405932 7767812 Minus 123525-123713
406400 9256298 Plus 1553-1712,1878-2140,4252-4385,5922-6077
Table 77 provides Pkey, Seq ID No, Disease Indications, and Preferred Utility for sequences in Table 78 Seq ID No links the information in Table 77 to Table 78
Seq ID No Sequence ID No for sequences in table
Pkey Unique Eos probeset identifier number
Disease Indications Diseases designated for coverage as described in Table 1
Preferred Utility Preference of utility, based partly upon predicted localization (Ab is antibody, sm is small molecule target, CTL is vaccine target)
Seq ID No Pkey Disease Indications PreferredUtility
10 Seq ID 1 8, 2 425023 angiogenesis Ab, sm, CTL, imaging Seq lD 3 & 4 424503 pancreas, prostate, angiogenesis, bladder, lung Ab, sm, imaging Seq ID 58, 6 429423 angiogenesis Ab, sm Seq ID 7 & 8 400289 angiogenesis, bladder, lung, cervical, ovanan, head 8, neck Ab, sm, CTL, diagnostic Seq ID 9 & 10 419172 angiogenesis, renal Ab, sm, CTL, imaging 15 Seq ID 11 & 12 418007 angiogenesis, lung, bladder, fibrosis, head 8, neck, pancreas, stomach, colon, ovanan Ab, sm, diagnostic
Seq ID 138, 14 418007 angiogenesis, lung, bladder, fibrosis, head & neck, pancreas, stomach, colon, ovanan Ab, sm, diagnostic Seq ID 158, 16 407836 angiogenesis CTL Seq ID 17 & 18 414577 angiogenesis Ab, CTL, diagnostic Seq ID 19 & 20 418738 angiogenesis, lung, ovanan, bladder & stomach, pancreas, utenne Ab, sm, CTL, imaging 0 Seq ID 21 & 22 428368 angiogenesis, head 8, neck, stomach Ab, sm, diagnostic
Seq ID 238 24 415138 angiogenesis, pancreas, stomach, lung, utenne Ab, CTL, diagnostic Seq ID 25 & 26 429276 angiogenesis, bladder, glioblastoma Ab, sm, imaging Seq ID 27 & 28 418994 prostate, angiogenesis Ab, CTL, imaging _ . Seq ID 29 & 30 407975 angiogenesis, renal Ab, CTL, diagnostic
25 Seq ID 31 & 32 429113 angiogenesis, bladder and stomach sm, CTL
Seq ID 33834 418506 angiogenesis, ovanan, glioblastoma, uterine, lung, bladder, pancreas Ab, sm, imaging Seq ID 35836 423961 breast, colon, bladder, lung, fibrosis, pancreas, head and neck, ovanan Ab, sm, diagnostic Seq ID 37 & 38 414812 breast, bladder, lung, Fibrosis, pancreas, colon, head and neck, cervical, stomach, renal, ovanan Ab, CTL, diagnostic Seq ID 39 & 40 417433 pancreas, breast, bladder, lung, head 8, neck, cervical, Utenne, ovanan, stomach, renal Ab.CTL, imaging 30 Seq ID 41 842 417433 pancreas, breast, bladder, lung, head & neck, cervical, utenne, ovanan, stomach, renal Ab.CTL, imaging Seq ID 438, 44 424399 breast, utenne, head & neck Ab, CTL, diagnostic Seq ID 45 & 46 422867 breast, ovanan, prostate, pancreas, lung, colon, utenne Ab, CTL, diagnostic Seq ID 47848 428227 breast, lung, bladder, ovanan, head & neck, fibrosis, colon, stomach, cervical Ab, CTL, diagnostic Seq ID 49850 444381 breast, colon, bladder, lung, pancreas, head & neck, ovanan, stomach, utenne, renal, angiogenesis Ab, CTL, diagnostic 35 Seq ID 51 & 52 439569 breast, androgen withdrawal prostate, prostate, bladder Ab, CTL, diagnostic
Seq ID 53 & 54 411558 pancreas, prostate, stomach, breast, utenne, cervical, ovanan Ab, sm, imaging Seq ID 55 & 56 400303 breast, ovanan, pros, stomach, utenne, bladder lung head & neck Ab.sm, CTL, imaging Seq ID 578 58 411789 pancreas, lung, breast, stomach, head 8, neck, ovanan, utenne Ab, CTL, diagnostic Seq ID 59 & 60 428698 breast, colon, lung, pancreas, stomach, head & neck, ovanan Ab, sm, imaging 40 Seq ID 61 & 62 450098 breast, lung, stomach, utenne CTL
Seq ID 63864 421552 breast, ovanan, pancreas, cervical, utenne, prostate, lung, stomach, head 8, neck Ab, sm, CTL, diagnostic Seq ID 65 & 66 452747 breast, bladder, lung, head 8, neck, ovanan, stomach, utenne, pancreas Ab, imaging Seq ID 67 & 68 415539 breast, prostate, ovanan, cervical, utenne Ab.sm, CTL, imaging Seq ID 69 & 70 416636 breast, pancreas, utenne Ab.sm, CTL, imaging 45 Seq ID 71 & 72 416636 breast, pancreas, utenne Ab.sm, CTL, imaging
Seq ID 73874 409079 breast, prostate Ab.sm, CTL, imaging Seq ID 75 & 76 442082 breast, prostate, ovanan Ab, imaging Seq ID 77 & 78 400297 breast, bladder, colon, prostate Ab.sm, CTL, imaging Seq ID 79 & 80 451398 breast, ovanan CTL 50 Seq ID 81 & 82 429220 breast, prostate, benign prostate hyperplasia Ab, CTL, imaging
Seq ID 83884 421524 breast Ab.sm, CTL, imaging Seq ID 85 & 86 423242 breast, renal, ovanan, prostate, colon Ab, CTL, imaging Seq ID 87 & 88 423242 breast, renal, ovanan, prostate, colon CTL Seq ID 89 & 90 423242 breast, renal, ovanan, prostate, colon CTL 55 Seq ID 91 & 92 452190 breast, stomach, pancreas CTL
Seq ID 93894 452190 breast stomach, pancreas CTL Seq ID 95896 325372 breast CTL Seq ID 978, 98 450375 breast, ovanan, head 8, neck, pancreas, lung, colon Ab.sm, CTL, imaging , . Seq ID 998, 100 426215 breast, lung, renal, colon, ovanan, utenne Ab, CTL, diagnostic
60 Seq ID 101 & 102 425247 breast, ovarian, lung, colon, pancreas, head & neck, stomach, utenne, cervical, bladder Ab, sm, CTL, diagnostic
Seq ID 103 & 104 429353 breast, prostate Ab, sm, CTL, imaging Seq ID 105 & 106 429353 breast, prostate Ab, sm, CTL, imaging Seq ID 107 & 108 432201 breast, colon, lung chemo, ovanan, stomach, pancreas, utenne, cervical Ab, sm, CTL, imaging Seq ID 109 & 110 427585 breast, lung, head & neck, pancreas, stomach, colon, ovanan, cervical CTL 65 Seq ID 111 & 112 446163 breast, cervical, utenne Ab, sm, imaging
Seq ID 113 & 114 442117 breast, lung, bladder, pancreas, head & neck, stomach, ovanan, prostate Ab, CTL, imaging Seq ID 115 & 116 428179 breast sm, CTL Seq ID 117 & 118 431211 colon, bladder, lung, pancreas, head & neck Ab, sm, imaging Seq ID 119 & 120 447033 colon, prostate, fibrosis, breast lung pancreas Ab, CTL, diagnostic 70 Seq ID 121 & 122 447033 colon, prostate, fibrosis, breast lung pancreas Ab, CTL, diagnostic
Seq ID 123 & 124 447033 colon, prostate, fibrosis, breast, lung pancreas Ab, CTL, diagnostic Seq ID 125 8 126 115522 colon, lung, bladder, pancreas CTL Seq ID 1278, 128 452679 prostate, colon, pancreas, Taxol prostate Ab.CTL, imaging Seq ID 129 & 130 446051 colon, breast Ab, sm, CTL, imaging 75 Seq ID 131 & 132 422048 colon, pancreas, prostate diagnostic
Seq ID 133 & 134 410418 colon, bladder, lung, ovanan, pancreas, head & neck Ab, sm, CTL, imaging Seq ID 135 & 136 446342 utenne, colon, prostate Ab, sm, CTL, imaging Seq ID 137 & 138 422260 colon, ovanan mucinous Ab, sm, CTL, diagnostic Seq ID 1398, 140 409041 utenne, ovanan, lung, colon, stomach, head & neck, breast, pancreas Ab, CTL, diagnostic 80 Seq ID 141 8, 142 409041 utenne, ovanan, lung, colon, stomach, head 8, neck, breast, pancreas Ab, CTL, diagnostic
Seq ID 143 & 144 111929 colon, breast, fibrosis Ab, sm, imaging Seq ID 1458 146 111929 colon, breast, fibrosis Ab, sm, imaging Seq ID 1478, 148 111929 colon, breast, fibrosis Ab, sm, imaging Seq ID 149 & 150 104888 colon, stomach, utenne Ab, imaging Seq ID 151 & 152 420159 bladder, stomach Ab, sm, CTL, imaging Seq ID 153 & 154 422330 pancreas, colon, bladder Ab.sm, CTL, imaging, diagnostic Seq ID 155 & 156 452461 bladder, lung, head & neck, ovanan glioblastoma, stomach, colon, cervical CTL Seq ID 157 & 158 413324 bladder Ab, sm, CTL, diagnostic
Seq ID 159 & 160 412420 bladder, glioblastoma, lung, stomach Ab, diagnostic Seq ID 161 & 162 416658 lung, ovanan, utenne, bladder Ab, CTL, diagnostic Seq ID 163 & 164 407811 bladder, pancreas, stomach, utenne lung Ab, sm, diagnostic Seq ID 165 402230 bladder sm, CTL Seq ID 166 & 167 402230 bladder sm, CTL
Seq ID 168 & 169 432829 bladder CTL Seq ID 170 & 171 425721 bladder Ab, imaging Seq ID 172 & 173 420370 bladder Ab, CTL-imaging Seq ID 174 & 175 437852 bladder, lung Ab, sm, CTL, imaging Seq ID 176 & 177 402075 bladder, lung, head & neck, cervical diagnostic
Seq ID 178 & 179 421110 bladder, pancreas, stomach, ovanan, lung Ab, sm, diagnostic Seq ID 180 & 181 451668 bladder, ovanan, lung Ab, sm, CTL, diagnostic Seq ID 182 & 183 451668 bladder, ovanan, lung Ab, sm, CTL, diagnostic Seq ID 184 & 185 451668 bladder, ovanan, lung Ab, sm, CTL, diagnostic Seq ID 186 & 187 408243 bladder, stomach, head 8, neck, cervical Ab, diagnostic
Seq ID 188 & 189 422282 bladder, lung, head & neck CTL, diagnostic Seq ID 190 & 191 425852 bladder, lung, head 8 neck Ab, sm, CTL, imaging Seq ID 192 & 193 439738 bladder, lung, cervical Ab, sm, CTL, imaging Seq ID 194 & 195 404875 bladder sm, CTL Seq ID 196 & 197 425883 bladder, pancreas Ab.CTL, imaging
Seq ID 198 & 199 404977 bladder, ovarian Ab, sm, CTL, diagnostic Seq ID 200 & 201 420876 pancreas, bladder Ab.sm, CTL, imaging Seq ID 2028, 203 427747 bladder, lung, ovanan, stomach sm, CTL Seq ID 204 & 205 420281 lung, bladder, ovanan, pancreas Ab, sm, imaging Seq ID 206 & 207 446673 bladder sm, CTL
Seq ID 208 437553 bladder Ab.CTL, imaging
Seq ID 209 & 210 437553 bladder Ab.CTL, imaging Seq ID 211 & 212 437553 bladder Ab.CTL, imaging Seq ID 213 & 214 426900 bladder, prostate Ab.CTL, imaging Seq ID 215 & 216 426900 bladder, prostate Ab.CTL, imaging
Seq ID 217 & 218 426900 bladder, prostate Ab.CTL, imaging Seq ID 219 & 220 405932 bladder, lung, head 8, neck, cervical sm Seq ID 221 & 222 405932 bladder, lung, head & neck, cervical sm Seq ID 223 & 224 424008 bladder, head 8 neck, stomach, cervical Ab.sm, CTL, imaging Seq ID 225 & 226 424008 bladder, head & neck, stomach, cervical Ab.sm, CTL, imaging Seq ID 227 & 228 424008 bladder, head & neck, stomach, cervical Ab.sm, CTL, imaging Seq ID 2298, 230 444342 hepatitis C, lung, fibrosis, bladder Ab, CTL, diagnostic Seq ID 231 & 232 421379 breast pancreas, head 8, neck, lung, stomach, bladder, cervical, colon Ab, CTL, diagnostic Seq ID 233 & 234 417079 bladder, lung, head & neck, cervical Ab, diagnostic Seq ID 235 & 236 412986 glioblastoma Ab.sm, CTL, imaging
Seq ID 237 & 238 412986 glioblastoma Ab.sm, CTL, imaging Seq ID 239 & 240 412986 glioblastoma Ab.sm, CTL, imaging Seq ID 241 & 242 447072 glioblastoma, pancreas sm, CTL Seq ID 243 & 244 419723 glioblastoma Ab, CTL, diagnostic Seq ID 245 & 246 419723 glioblastoma Ab.sm, CTL, imaging
Seq ID 247 & 248 430890 glioblastoma, lung, cervical, bladder Ab, CTL, imaging, diagnostic Seq ID 2498, 250 456759 glioblastoma Ab.sm, CTL, imaging Seq ID 251 429466 glioblastoma, utenne
Seq ID 252 429466 glioblastoma, utenne Seq ID 253 & 254 419721 glioblastoma, lung Ab.sm, CTL, imaging
Seq ID 255 & 256 407034 glioblastoma Ab, CTL, diagnostic Seq ID 257 & 258 413472 glioblastoma Ab.sm, CTL, imaging Seq ID 2598, 260 438380 glioblastoma Ab, CTL, diagnostic, imaging Seq ID 261 & 262 426271 glioblastoma Ab, CTL, diagnostic Seq ID 263 & 264 419704 glioblastoma sm, CTL
Seq ID 265 & 266 444471 glioblastoma, lung, colon Ab.sm, CTL, imaging Seq ID 267 & 268 409395 glioblastoma Ab, CTL, diagnostic Seq ID 269 & 270 413063 glioblastoma, ovanan, bladder, lung Ab, CTL, diagnostic Seq ID 271 & 272 433800 glioblastoma, lung Ab, CTL, imaging Seq ID 273 458435 glioblastoma
Seq ID 274 458435 glioblastoma
Seq ID 275 & 276 424343 glioblastoma, ovanan, utenne Ab.sm, CTL, imaging Seq ID 277 & 278 424998 glioblastoma Ab, CTL, diagnostic Seq ID 279 & 280 412709 glioblastoma Ab.sm, CTL, imaging Seq ID 281 8,282 435615 glioblastoma Ab.sm, CTL, imaging
Seq ID 283 & 284 404049 glioblastoma Ab.sm, CTL, imaging Seq ID 285 & 286 418932 glioblastoma Ab.sm, CTL, imaging Seq ID 287 & 288 404029 glioblastoma Ab.sm, CTL, imaging Seq ID 289 & 290 436480 glioblastoma sm, CTL Seq ID 291 & 292 452401 bladder, breast, pancreas, head & neck, stomach, lung, arthntis, renal Ab, CTL, diagnostic
Seq ID 293 & 294 452401 bladder, breast, pancreas, head & neck, stomach, lung, arthntis, renal Ab, CTL, diagnostic Seq ID 295 8, 296 436895 breast, renal, ovanan, glioblastoma Ab.sm, imaging Seq ID 297 & 298 421471 renal Ab.sm, CTL, imaging Seq ID 299 & 300 428296 renal Ab.sm, CTL, imaging Seq ID 301 & 302 423508 renal, colon Ab, CTL, imaging
Seq ID 303 & 304 450001 renal, lung Ab,sm, CTL, imaging Seq ID 305 & 306 410407 renal, lung, colon, stomach, ovanan, utenne Ab.s , CTL, imaging Seq ID 307 & 308 453496 renal, prostate Ab.sm, CTL, imaging Seq ID 309 & 310 420737 renal Ab.sm, CTL, imaging Seq ID 311 & 312 309931 lung Ab.sm, CTL, imaging Seq ID 313 & 314 412719 lung, head & neck, bladder, glioblastoma, cervical CTL Seq ID 315 & 316 417034 lung, head & neck, a couple cervical Ab, CTL, diagnostic 5 Seq ID 3178318 430486 lung, bladder, head 8 neck, cervical Ab.sm, imaging
Seq ID 319 & 320 413753 lung, bladder, head & neck, pancreas, cervical, colon CTL, diagnostic Seq ID 321 8322 425650 lung, head 8 neck, cervical, bladder Ab, imaging Seq ID 3238324 423673 bladder, lung, head & neck, ovarian, pancreas, colon, stomach, uterine, cervical Ab, CTL, diagnostic Seq ID 3258326 418663 lung, bladder, head 8 neck, cervical Ab, imaging 10 Seq ID 327 & 328 418663 lung, bladder, head 8 neck, cervical Ab, imaging
Seq ID 3298330 429610 lung CTL, diagnostic Seq ID 331 8332 406690 lung, head & neck, pancreas, stomach, bladder, colon, cervical Ab, imaging Seq ID 3338334 431846 lung, bladder, head & neck, uterine, cervical, stomach, ovarian Ab, imaging Seq ID 3358336 422158 head & neck, bladder, lung, cervical, stomach diagnostic 15 Seq ID 3378338 431958 lung, bladder, cervical, head & neck, ovarian, colon, prostate, pancreas, breast Ab, CTL, imaging
Seq ID 339 & 340 437044 head 8 neck, cervical, lung, bladder, breast, prostate, ovarian, stomach Ab, imaging Seq ID 341 8342 428484 lung, glioblastoma, bladder, head & neck, colon, cervical Ab, sm, imaging Seq ID 3438344 429211 lung, bladder, head & neck, cervical, stomach Ab, imaging Seq ID 3458, 346 417389 ovarian, lung, bladder, uterine, cervical, pancreas, stomach Ab, diagnostic 0 Seq ID 347 & 348 431009 lung, bladder, head & neck Ab, sm, imaging
Seq ID 3498350 417542 lung CTL, diagnostic Seq ID 351 8352 449230 lung, cervical, head 8 neck, bladder, ovarian, colon Ab, imaging Seq ID 353 & 354 410555 lung Ab, sm, imaging _ _ Seq ID 3558356 410555 lung Ab, sm, imaging
25 Seq ID 3578358 424687 head & neck, pancreas, lung, uterine, cervical, colon, stomach Ab, sm, diagnostic
Seq ID 3598360 418462 lung, bladder Ab, imaging Seq ID 361 8362 410274 lung, renal diagnostic Seq ID 363 & 364 439606 lung, bladder, head 8 neck, cervical Ab.sm, imaging Seq ID 3658366 404877 lung, bladder CTL 30 Seq ID 367 & 368 444781 lung, bladder, head 8 neck, cervical Ab, imaging
Seq ID 3698370 109424 bladder, lung Ab, sm, CTL, imaging Seq ID 371 & 372 415817 lung, glioblastoma, head & neck, cervical, fibrosis Ab.s , CTL, imaging Seq ID 3738374 415817 lung, glioblastoma, head & neck, cervical, fibrosis Ab.sm, CTL, imaging Seq ID 3758376 415817 lung, glioblastoma, head 8 neck, cervical, fibrosis Ab.sm, CTL, imaging 35 Seq ID 3778378 415817 lung, glioblastoma, head 8 neck, cervical, fibrosis Ab.sm, CTL, imaging
Seq ID 379 & 380 415817 lung, glioblastoma, head 8 neck, cervical, fibrosis Ab.sm, CTL, imaging Seq ID 381 & 382 415817 lung, glioblastoma, head 8 neck, cervical, fibrosis Ab.sm, CTL, imaging Seq ID 3838384 421817 lung, cervical, head 8 neck 8 bladder Ab.sm, CTL, imaging Seq ID 3858386 418678 lung, bladder, stomach, ovarian, pancreas & cervical CTL 40 Seq ID 3878388 418678 lung, bladder, stomach, ovarian, pancreas & cervical CTL Seq ID 3898390 409420 lung, head & neck, pancreas, stomach, cervical, bladder CTL, diagnostic Seq ID 391 8392 332180 lung Ab, sm, imaging Seq ID 3938394 408790 lung Ab.sm, CTL, imaging Seq ID 3958396 408790 lung Ab.sm, CTL, imaging 45 Seq ID 3978398 439223 lung, head & neck, cervical, bladder & colon Ab, CTL, imaging
Seq ID 3998400 409757 pancreas, stomach, lung, bladder, stomach Ab, CTL, diagnostic Seq ID 401 402 428969 lung, cervical Ab, CTL, diagnostic Seq ID 403 & 404 428969 lung, cervical Ab, CTL, diagnostic Seq ID 4058406 428969 lung, cervical Ab, CTL, diagnostic 50 Seq ID 407 & 408 428969 lung, cervical Ab, CTL, diagnostic Seq ID 409 & 410 450701 lung, head & neck, pancreas, breast, stomach, ovarian, colon Ab, CTL, diagnostic Seq lD 411 & 412 450701 lung, head & neck, pancreas, breast, stomach, ovarian, colon Ab, CTL, diagnostic Seq ID 413 & 414 414774 lung, bladder, head & neck, pancreas, stomach, ovarian Ab, sm, diagnostic Seq ID 415 & 416 407944 lung, head & neck Ab, sm, imaging 55 Seq ID 417 & 418 407944 lung, head 8 neck Ab, sm, imaging
Seq ID 419 & 420 428486 pancreas Ab, CTL, diagnostic Seq ID 421 8422 457489 pancreas, prostate, lung Ab, CTL, diagnostic Seq ID 4238424 432874 pancreas, stomach Ab, CTL, diagnostic Seq ID 4258426 445891 stomach, pancreas, ovarian Ab, CTL, imaging 60 Seq ID 4278428 445891 stomach, pancreas, ovarian Ab, CTL, imaging Seq ID 4298430 404682 pancreas Ab, CTL, diagnostic Seq ID 431 8432 429547 pancreas, head 8, neck, lung, ovarian Ab, CTL, diagnostic Seq ID 433 & 434 425921 stomach, pancreas Ab.sm, CTL, imaging Seq ID 435 & 436 407242 pancreas, colon, bladder, head & neck, stomach, lung, ovarian, cervical Ab.sm, CTL, imaging 65 Seq ID 437 & 438 407242 pancreas, colon, bladder, head & neck, stomach, lung, ovarian, cervical Ab.sm, CTL, imaging
Seq ID 439 & 440 407242 pancreas, colon, bladder, head 8 neck, stomach, lung, ovarian, cervical Ab.sm, CTL, imaging Seq ID 441 8442 432596 pancreas, breast CTL Seq ID 443 & 444 444006 pancreas, colon, lung, ovarian & cervical Ab, CTL, imaging Seq ID 445 & 446 423685 pancreas, uterine, colon CTL 70 Seq ID 447 & 448 428392 pancreas Ab, CTL, diagnostic Seq ID 449 & 450 429597 pancreas, colon, stomach, lung Ab.sm, CTL, imaging Seq ID 451 8452 448030 pancreas, renal and stomach, Ab.sm, imaging Seq ID 453 & 454 422109 pancreas, lung, colon Ab, CTL, diagnostic Seq ID 4558456 419235 pancreas, fibrosis, head 8 neck 8 lung Ab, CTL, imaging 75 Seq ID 4578458 449048 pancreas, ovarian, uterine, glioblastoma, head & neck 8 lung Ab, CTL, imaging
Seq ID 4598460 427333 pancreas, colon Ab, sm, imaging Seq ID 461 8462 417931 ovarian, pancreas, stomach, colon, uterine, prostate Ab, diagnostic Seq ID 463 464 419216 pancreas, lung, stomach, cervical, prostate, head & neck Ab, CTL, diagnostic o n Seq ID 4658466 431629 pancreas, uterine, cervical, stomach Ab, CTL, diagnostic θ Seq ID 467 & 468 413554 pancreas, glioblastoma Ab, CTL, diagnostic
Seq ID 4698470 452194 stomach, pancreas, renal, colon Ab.s , CTL, imaging Seq ID 471 8472 452194 stomach, pancreas, renal, colon Ab.sm, CTL, imaging Seq ID 4738474 426322 pancreas, bladder, stomach Ab, diagnostic Seq ID 475 & 476 429010 pancreas sm, CTL Seq ID 4778478 431462 pancreas, lung, glioblastoma Ab, diagnostic Seq ID 479 480 448243 ovanan, utenne, lung, stomach, head & neck, glioblastoma, pancreas Ab.sm, imaging Seq ID 481 8482 426427 ovanan, lung, head _ neck, cervical, colon, utenne, stomach sm, CTL 5 Seq ID 483 & 484 428187 ovanan, utenne, colon, stomach Ab.sm, CTL, imaging
Seq ID 4858486 428579 ovanan, Ewing, utenne, pancreas Ab.sm, CTL, imaging Seq ID 4878488 428579 ovanan, Ewing utenne pancreas Ab.sm, CTL, imaging Seq ID 489 & 490 428579 ovarian, Ewing, utenne, pancreas Ab.sm, CTL, imaging Seq ID 491 8492 428579 ovanan, Ewing, utenne, pancreas Ab.sm, CTL, imaging 0 Seq ID 4938494 445537 ovanan, bladder, utenne, breast, lung head & neck, renal, fibrosis, pancreas, cervical Ab, CTL, diagnostic
Seq ID 4958496 422278 ovanan, head & neck, bladder, cervical, lung Ab.sm, imaging Seq ID 4978498 424620 ovanan Ab, CTL, diagnostic Seq ID 4998500 406400 ovanan, utenne Ab, CTLrdiagnostic Seq ID 501 8502 431130 ovanan, utenne Ab, CTL, diagnostic 5 Seq ID 503 & 504 420440 ovanan, utenne, cervical Ab, CTL, diagnostic
Seq ID 505 & 506 428450 ovanan, cervical pancreas, lung sm Seq ID 507 & 508 446619 ovanan, fibrosis, pancreas, head 8, neck, lung, colon Ab, diagnostic Seq ID 5098510 436982 ovanan, fibrosis Ab, CTL, diagnostic Seq ID 511 8512 453392 ovanan, lung, glioblastoma CTL 0 Seq ID 513 431989 ovanan
Seq ID 514 439820 ovanan, uterine, cervical, breast, prostate
Seq ID 515 & 516 409178 ovanan, breast Ab, CTL, diagnostic Seq ID 517 518 426514 ovanan, colon, bladder, lung, cervical Ab, CTL, diagnostic Seq ID 519 & 520 421478 ovanan, bladder Ab, CTL, imaging 5 Seq ID 521 & 522 421478 ovanan, bladder Ab, CTL, imaging
Seq ID 5238524 425776 ovanan, utenne, lung Ab.sm, CTL, imaging Seq ID 525 & 526 425776 ovanan, utenne, lung Ab.sm, CTL, imaging Seq ID 527 & 528 452097 ovanan Ab, sm, diagnostic Seq ID 5298 530 416530 ovanan, utenne Ab, CTL, diagnostic 0 Seq ID 531 8532 431515 ovanan, prostate, lung Ab,sm, CTL, imaging
Seq ID 5338534 419452 ovanan, prostate, lung, breast uterine Ab.sm, CTL, imaging Seq ID 535 & 536 412078 ovanan CTL Seq ID 537 & 538 412078 ovanan CTL Seq ID 5398540 411773 ovanan Ab, sm, CTL diagnostic 5 Seq ID 541 & 542 407792 ovanan, utenne, cervical, pancreas Ab, CTL, diagnostic
Seq ID 543 & 544 431616 prostate, pancreas, colon Ab.sm, CTL, imaging Seq ID 545 & 546 452792 prostate, utenne, breast Ab, CTL, imaging Seq ID 547 & 548 400294 prostate, taxol prostate Ab.sm, CTL, imaging . Λ Seq ID 549 &550 432653 prostate, lung Ab.sm, CTL, imaging 0 Seq ID 551 8552 432653 prostate, lung Ab.sm, CTL, imaging
Seq ID 5538554 432653 prostate, lung Ab.sm, CTL, imaging Seq ID 5558556 432653 prostate, lung Ab.sm, CTL, imaging Seq ID 557 & 558 400290 prostate, colon Ab.sm, CTL, imaging Seq ID 5598, 560 410001 ovanan, prostate, utenne, cervical, lung Ab, CTL, diagnostic 5 Seq ID 561 & 562 418396 prostate Ab.sm, CTL, imaging
Seq ID 5638564 451027 prostate, utenne, glioblastoma Ab.sm, CTL, imaging Seq ID 565 & 566 446057 prostate Ab.sm, CTL, imaging Seq ID 5678568 433466 prostate Ab, CTL, diagnostic Seq ID 5698570 453370 prostate Ab.sm, CTL, imaging 0 Seq ID 571 & 572 453370 prostate Ab,sm, CTL, imaging
Seq ID 5738574 414569 prostate Ab.sm, CTL, imaging Seq ID 575 & 576 413435 prostate, glioblastoma, pancreas Ab, sm, diagnostic Seq ID 577 & 578 426501 prostate, breast, glioblastoma, lung Ab, CTL, imaging _ . Seq ID 579 & 580 448999 prostate, glioblastoma Ab.sm, CTL, imaging 5 Seq ID 581 8582 408369 prostate, lung, fibrosis, utenne, glioblastoma, cervical, ovanan Ab.sm, CTL, imaging
Seq ID 583 & 584 412628 prostate Ab, CTL, diagnostic Seq ID 5858586 403047 prostate, bladder, colon Ab.sm, CTL, imaging Seq ID 5878588 403047 prostate, bladder, colon Ab.sm, CTL, imaging Seq ID 589 & 590 408430 prostate Ab.sm, CTL, imaging 60 Seq ID 591 & 592 445413 prostate, colon, utenne, ovanan, lung, pancreas diagnostic
Seq ID 5938594 451982 prostate, bladder CTL Seq ID 595 & 596 427958 prostate, glioblastoma Ab.sm, CTL, imaging Seq ID 597 598 421887 prostate Ab, CTL, imaging Seq ID 599 & 600 425071 prostate, colon, stomxh, utenne, cervical, head _ neck, pancreas Ab, diagnostic 65 Seq ID 601 & 602 432101 prostate, pancreas Ab.sm, imaging
Seq ID 603 604 407786 prostate, colon, utenne, stomach, inflammatory bowel disease, ovanan Ab.sm, imaging Seq ID 605 & 606 416836 Prostate, Ewing, glioblastoma Ab, CTL, diagnostic Seq ID 607 & 608 416539 ZD1839 resistant cancers, head & neck Ab, sm, CTL, imaging Seq ID 609 & 610 131083 androgen withdrawal prostate Ab, sm, CTL, imaging 70 Seq ID 611 & 612 131083 androgen withdrawal prostate Ab, sm, CTL, imaging
Seq ID 613 & 614 131083 androgen withdrawal prostate Ab, sm, CTL, imaging Seq ID 6158616 131083 androgen withdrawal prostate Ab, sm, CTL, imaging Seq ID 6178618 422424 bladder, pancreas, prostate, angiogenesis, colon, stomach, lung Ab, CTL, diagnostic Seq ID 619 & 620 428970 stomach, pancreas, colon Ab.sm, imaging 75 Seq ID 621 & 622 428330 utenne, ovanan, fibrosis, prostate, pancreas, lung, bladder, head 8, neck Ab, sm, CTL, diagnostic
Seq ID 6238624 439018 utenne, stomxh, prostate Ab.sm, CTL, imaging Seq ID 6258626 420610 utenne, ovanan endometnoid, lung CTL Seq ID 6278628 425723 ovanan endometnoid, utenne, colon Ab, CTL, diagnostic Seq ID 6298630 456662 utenne, ovanan CTL 80 Seq ID 631 & 632 418281 utenne, ovanan Ab, CTL, diagnostic
Seq ID 6338634 429903 lung sm
I Table 78
Seq ID NO: 1 DNA sequence
Nucleic Acid Accession #: NM_001400
Coding sequence: 251. .1399
1 11 21 31 41 51 1 1 11 11 11 11 11
TCTAAAGGTC GGGGGCAGCA GCAAGATGCG AAGCGAGCCG TACAGATCCC GGGCTCTCCG 60
AACGCAACTT CGCCCTGCTT GAGCGAGGCT GCGGTTTCCG AGGCCCTCTC CAGCCAAGGA 120
AAAGCTACAC AAAAAGCCTG GATCACTCAT CGAACCACCC CTGAAGCCAG TGAAGGCTCT 180
CTCGCCTCGC CCTCTAGCGT TCGTCTGGAG TAGCGCCACC CCGGCTTCCT GGGGACACAG 240
GGTTGGCACC ATGGGGCCCA CCAGCGTCCC GCTGGTCAAG GCCCACCGCA GCTCGGTCTC 300
TGACTACGTC AACTATGATA TCATCGTCCG GCATTACAAC TACACGGGAA AGCTGAATAT 360
CAGCGCGGAC AAGGAGAACA GCATTAAACT GACCTCGGTG GTGTTCATTC TCATCTGCTG 420
CTTTATCATC CTGGAGAACA TCTTTGTCTT GCTGACCATT TGGAAAACCA AGAAATTCCA 480
CCGACCCATG TACTATTTTA TTGGCAATCT GGCCCTCTCA GACCTGTTGG CAGGAGTAGC 540
CTACACAGCT AACCTGCTCT TGTCTGGGGC CACCACCTAC AAGCTCACTC CCGCCCAGTG 600
GTTTCTGCGG GAAGGGAGTA TGTTTGTGGC CCTGTCAGCC TCCGTGTTCA GTCTCCTCGC 660
CATCGCCATT GAGCGCTATA TCACAATGCT GAAAATGAAA CTCCACAACG GGAGCAATAA 720
CTTCCGCCTC TTCCTGCTAA TCAGCGCCTG CTGGGTCATC TCCCTCATCC TGGGTGGCCT 780
GCCTATCATG GGCTGGAACT GCATCAGTGC GCTGTCCAGC TGCTCCACCG TGCTGCCGCT 840
CTACCACAAG CACTATATCC TCTTCTGCAC CACGGTCTTC ACTCTGCTTC TGCTCTCCAT 900
CGTCATTCTG TACTGCAGAA TCTACTCCTT GGTCAGGACT CGGAGCCGCC GCCTGACGTT 960
CCGCAAGAAC ATTTCCAAGG CCAGCCGCAG CTCTGAGAAG TCGCTGGCGC TGCTCAAGAC 1020
CGTAATTATC GTCCTGAGCG TCTTCATCGC CTGCTGGGCA CCGCTCTTCA TCCTGCTCCT 1080
GCTGGATGTG GGCTGCAAGG TGAAGACCTG TGACATCCTC TTCAGAGCGG AGTACTTCCT 1140
GGTGTTAGCT GTGCTCAACT CCGGCACCAA CCCCATCATT TACACTCTGA CCAACAAGGA 1200
GATGCGTCGG GCCTTCATCC GGATCATGTC CTGCTGCAAG TGCCCGAGCG GAGACTCTGC 1260
TGGCAAATTC AAGCGACCCA TCATCGCCGG CATGGAATTC AGCCGCAGCA AATCGGACAA 1320
TTCCTCCCAC CCCCAGAAAG ACGAAGGGGA CAACCCAGAG ACCATTATGT CTTCTGGAAA 1380
CGTCAACTCT TCTTCCTAGA ACTGGAAGCT GTCCACCCAC CGGAAGCGCT CTTTACTTGG 1440
TCGCTGGCCA CCCCAGTGTT TGGAAAAAAA TCTCTGGGCT TCGACTGCTG CCAGGGAGGA 1500
GCTGCTGCAA GCCAGAGGGA GGAAGGGGGA GAATACGAAC AGCCTGGTGG TGTCGGGTGT 1560
TGGTGGGTAG AGTTAGTTCC TGTGAACAAT GCACTGGGAA GGGTGGAGAT CAGGTCCCGG 1620
CCTGGAATAT ATATTCTACC CCCCTGGAGC TTTGATTTTG CACTGAGCCA AAGGTCTAGC 1680
ATTGTCAAGC TCCTAAAGGG TTCATTTGGC CCCTCCTCAA AGACTAATGT CCCCATGTGA 1740
AAGCGTCTCT TTGTCTGGAG CTTTGAGGAG ATGTTTTCCT TCACTTTAGT TTCAAACCCA 1800
AGTGAGTGTG TGCACTTCTG CTTCTTTAGG GATGCCCTGT ACATCCCACA CCCCACCCTC 1860
CCTTCCCTTC ATACCCCTCC TCAACGTTCT TTTACTTTAT ACTTTAACTA CCTGAGAGTT 1920
ATCAGAGCTG GGGTTGTGGA ATGATCGATC ATCTATAGCA AATAGGCTAT GTTGAGTACG 1980
TAGGCTGTGG GAAGATGAAG ATGGTTTGGA GGTGTAAAAC AATGTCCTTC GCTGAGGCCA 2040
AAGTTTCCAT GTAAGCGGGA TCCGTTTTTT GGAATTTGGT TGAAGTCACT TTGATTTCTT 2100
TAAAAAACAT CTTTTCAATG AAATGTGTTA CCATTTCATA TCCATTGAAG CCGAAATCTG 2160
CATAAGGAAG CCCACTTTAT CTAAATGATA TTAGCCAGGA TCCTTGGTGT CCTAGGAGAA 2220
ACAGACAAGC AAAACAAAGT GAAAACCGAA TGGATTAACT TTTGCAAACC AAGGGAGATT 2280
TCTTAGCAAA TGAGTCTAAC AAATATGACA TCCGTCTTTC CCACTTTTGT TGATGTTTAT 2340
TTCAGAATCT TGTGTGATTC ATTTCAAGCA ACAACATGTT GTATTTTGTT GTGTTAAAAG 2400
TACTTTTCTT GATTTTTGAA TGTATTTGTT TCAGGAAGAA GTCATTTTAT GGATTTTTCT 2460
AACCCGTGTT AACTTTTCTA GAATCCACCC TCTTGTGCCC TTAAGCATTA CTTTAACTGG 2520
TAGGGAACGC CAGAACTTTT AAGTCCAGCT ATTCATTAGA TAGTAATTGA AGATATGTAT 2580
AAATATTACA AAGAATAAAA ATATATTACT GTCTCTTTAG TATGGTTTTC AGTGCAATTA 2640
AACCGAGAGA TGTCTTGTTT TTTTAAAAAG AATAGTATTT AATAGGTTTC TGACTTTTGT 2700
GGATCATTTT GCACATAGCT TTATCAACTT TTAAACATTA ATAAACTGAT TTTTTTAAAG
Seq ID NO: 2 Protein sequence
Protein Accession #: NP_001391
1 11 21 31 41 51 1 1 11 11 11 11 11 MGPTSVPLVK AHRSSVSDYV NYDIIVRHYN YTGKLNISAD KENSIKLTSV VFI ICCFII 60 ENIFVLLTI WKTKKFHRPM YYFIGNA S D LAGVAYTA N LLSGATTY KLTPAQWFLR 120
EGS FVALSA SVFS LAIAI ERYITM KMK HNGSNNFRL F LISACWVI S ILGGLPIM 180
G NCISALSS CSTVLP YHK HYILFCTTVF TL L SIVIL YCRIYS VRT RSRRLTFRKN 240
ISKASRSSEK S A LKTVII V SVFIACWA PLFIL LDV GCKVKTCDI FRAEYFLVIA 300
V NSGTNPII YT TNKEMRR AFIRIMSCCK CPSGDSAGKF KRPIIAGMEF SRSKSDNSSH 360
PQKDEGDNPE TIMSSGNVNS SS
Seq ID NO: 3 DNA sequence
Nucleic Acid Accession #: NM_002205.1
Coding sequence: 1..3149
1 11 21 31 41 51 1 1 11 11 11 11 11 ATGGGGAGCC GGACGCCAGA GTCCCCTCTC CACGCCGTGC AGCTGCGCTG GGGCCCCCGG 60
CGCCGACCCC CGCTSSTGCC GCTGCTGTTG CTGCTSSTGC GGCCGCCACC CAGGGTCGGG 120
GGCTTCAACT TAGACGCGGA GGCCCCAGCA GTACTCTCGG GGCCCCCGGG CTCCTTCTTC 180
GGATTCTCAG TGGAGTTTTA CCGGCCGGGA ACAGACGGGG TCAGTGTGCT GGTGGGAGCA 240
CCCAAGGCTA ATACCAGCCA GCCAGGAGTG CTGCAGGGTG GTGCTGTCTA CCTCTGTCCT 300
TGGGGTGCCA GCCCCACACA GTGCACCCCC ATTGAATTTG ACAGCAAAGG CTCTCGGCTC 360
CTGGAGTCCT CACTGTCCAG CTCAGAGGGA GAGGAGCCTG TGGAGTACAA GTCCTTGCAG 420
TGGTTCGGGG CAACAGTTCG AGCCCATGGC TCCTCCATCT TGGCATGCGC TCCACTGTAC 480
AGCTGGCGCA CAGAGAAGGA GCCACTGAGC GACCCCGTGG GCACCTGCTA CCTCTCCACA 540
GATAACTTCA CCCGAATTCT GGAGTATGCA CCCTGCCGCT CAGATTTCAG CTGGGCAGCA 600 GGACAGGGTT ACTGCCAAGG AGGCTTCAGT GCCGAGTTCA CCAAGACTGG CCGTGTGGTT 660
TTAGGTGGAC CAGGAAGCTA TTTCTGGCAA GGCCAGATCC TGTCTGCCAC TCAGGAGCAG 720
ATTGCAGAAT CTTATTACCC CGAGTACCTG ATCAACCTGG TTCAGGGGCA GCTGCAGACT 780
CGCCAGGCCA GTTCCATCTA TGATGACAGC TACCTAGGAT ACTCTGTGGC TGTTGGTGAA 840
TTCAGTGGTG ATGACACAGA AGACTTTGTT GCTGGTGTGC CCAAAGGGAA CCTCACTTAC 900
GGCTATGTCA CCATCCTTAA TGGCTCAGAC ATTCGATCCC TCTACAACTT CTCAGGGGAA 960
CAGATGGCCT CCTACTTTGG CTATGCAGTG GCCGCCACAG ACGTCAATGG GGACGGGCTG 1020
GATGACTTGC TGGTGGGGGC ACCCCTGCTC ATGGATCGGA CCCCTGACGG GCGGCCTCAG 1080
GAGGTGGGCA GGGTCTACGT CTACCTGCAG CACCCAGCCG GCATAGAGCC CACGCCCACC 1140
CTTACCCTCA CTGGCCATGA TGAGTTTGGC CGATTTGGCA GCTCCTTGAC CCCCCTGGGG 1200
GACCTGGACC AGGATGGCTA CAATGATGTG GCCATCGGGG CTCCCTTTGG TGGGGAGACC 1260
CAGCAGGGAG TAGTGTTTGT ATTTCCTGGG GGCCCAGGAG GGCTGGGCTC TAAGCCTTCC 1320
CAGGTTCTGC AGCCCCTGTG GGCAGCCAGC CACACCCCAG ACTTCTTTGG CTCTGCCCTT 1380
CGAGGAGGCC GAGACCTGGA TGGCAATGGA TATCCTGATC TGATTGTGGG GTCCTTTGGT 1440
GTGGACAAGG CTGTGGTATA CAGGGGCCGC CCCATCGTGT CCGCTAGTGC CTCCCTCACC 1500
ATCTTCCCCG CCATGTTCAA CCCAGAGGAG CGGAGCTGCA GCTTAGAGGG GAACCCTGTG 1560
GCCTGCATCA ACCTTAGCTT CTGCCTCAAT GCTTCTGGAA AACACGTTGC TGACTCCATT 1620
GGTTTCACAG TGGAACTTCA GCTGGACTGG CAGAAGCAGA AGGGAGGGGT ACGGCGGGCA 1680
CTGTTCCTGG CCTCCAGGCA GGCAACCCTG ACCCAGACCC TGCTCATCCA GAATGGGGCT 1740
CGAGAGGATT GCAGAGAGAT GAAGATCTAC CTCAGGAACG AGTCAGAATT TCGAGACAAA 1800
CTCTCGCCGA TTCACATCGC TCTCAACTTC TCCTTGGACC CCCAAGCCCC AGTGGACAGC 1860
CACGGCCTCA GGCCAGCCCT ACATTATCAG AGCAAGAGCC GGATAGAGGA CAAGGCTCAG 1920
ATCTTGCTGG ACTGTGGAGA AGACAACATC TGTGTGCCTG ACCTGCAGCT GGAAGTGTTT 1980
GGGGAGCAGA ACCATGTGTA CCTGGGTGAC AAGAATGCCC TGAACCTCAC TTTCCATGCC 2040
CAGAATGTGG GTGAGGGTGG CGCCTATGAG GCTGAGCTTC GGGTCACCGC CCCTCCAGAG 2100
GCTGAGTACT CAGGACTCGT CAGACACCCA GGGAACTTCT CCAGCCTGAG CTGTGACTAC 2160
TTTGCCGTGA ACCAGAGCCG CCTGCTGGTG TGTGACCTGG GCAACCCCAT GAAGGCAGGA 2220
GCCAGTCTGT GGGGTGGCCT TCGGTTTACA GTCCCTCATC TCCGGGACAC TAAGAAAACC 2280
ATCCAGTTTG ACTTCCAGAT CCTCAGCAAG AATCTCAACA ACTCGCAAAG CGACGTGGTT 2340
TCCTTTCGGC TCTCCGTGGA GGCTCAGGCC CAGGTCACCC TGAACGGTGT CTCCAAGCCT 2400
GAGGCAGTGC TATTCCCAGT AAGCGACTGG CATCCCCGAG ACCAGCCTCA GAAGGAGGAG 2460
GACCTGGGAC CTGCTGTCCA CCATGTCTAT GAGCTCATCA ACCAAGGCCC CAGCTCCATT 2520
AGCCAGGGTG TGCTGGAACT CAGCTGTCCC CAGGCTCTGG AAGGTCAGCA GCTCCTATAT 2580
GTGACCAGAG TTACGGGACT CAACTGCACC ACCAATCACC CCATTAACCC AAAGGGCCTG 2640
GAGTTGGATC CCGAGGGTTC CCTGCACCAC CAGCAAAAAC GGGAAGCTCC AAGCCGCAGC 2700
TCTGCTTCCT CGGGACCTCA GATCCTGAAA TGCCCGGAGG CTGAGTGTTT CAGGCTGCGC 2760
TGTGAGCTCG GGCCCCTGCA CCAACAAGAG AGCCAAAGTC TGCAGTTGCA TTTCCGAGTC 2820
TGGGCCAAGA CTTTCTTGCA GCGGGAGCAC CAGCCATTTA GCCTGCAGTG TGAGGCTGTG 2880
TACAAAGCCC TGAAGATGCC CTACCGAATC CTGCCTCGGC AGCTGCCCCA AAAAGAGCGT 2940
CAGGTGGCCA CAGCTGTGCA ATGGACCAAG GCAGAAGGCA GCTATGGCGT CCCACTGTGG 3000
ATCATCATCC TAGCCATCCT GTTTGGCCTC CTGCTCCTAG GTCTACTCAT CTACATCCTC 3060
TACAAGCTTG GATTCTTCAA ACGCTCCCTC CCATATGGCA CCGCCATGGA AAAAGCTCAG 3120
CTCAAGCCTC CAGCCACCTC TGATGCCTGA
Seq ID NO: 4 Protein sequence Protein Accession #: NP 002196.1
31 51
MGSRTPESPL HAVQ RWGPR RRPPLLPLLI. LLLPPPPRVG GFNLDAEAPA VLSGPPGSFF 60
GFSVEFYRPG TDGVSVVGA PKANTSQPGV LQGGAVYLCP WGASPTQCTP IEFDSKGSRL 120
LESSLSSSEG EEPVEYKS Q WFGATVRAHG SSILACAPLY SWRTEKEP S DPVGTCY ST 180
DNFTRILEYA PCRSDFSWAA GQGYCQGGFS AEFTKTGRW LGGPGSYFWQ GQILSATQEQ 240
IAESYYPEYL INLVQGQLQT RQASSIYDDS YLGYSVAVGE FSGDDTEDFV AGVPKGNI.TY 300
GYVTI NGSD IRS YNFSGE QMASYFGYAV AATDVNGDGL DDL VGAPLL, MDRTPDGRPQ 360
EVGRVYVY Q HPAGIEPTPT T TGHDEFG RFGSSLTPLG D DQDGYNDV AIGAPFGGET 420
QQGWFVFPG GPGG GSKPS QV QPLWAAS HTPDFFGSAL RGGRDLDGNG YPDLIVGSFG 480
VDKAWYRGR PIVSASASLT IFPAMFNPEE RSCS EGNPV ACINLSFC N ASGKHVADSI 540
GFTVELQ DW QKQKGGVRRA LFLASRQATL TQTIiLIQNGA REDCREMKIY LRNESEFRDK 600 SPIHIALNF S DPQAPVDS HGIiRPAHYQ SKSRIEDKAQ IL DCGEDNI CVPDLQLEVF 660
GEQNHVYLGD KNALN TFHA QNVGEGGAYE AELRVTAPPE AEYSGLVRHP GNFSSLSCDY 720
FAVNQSRLLV CDLGNPMKAG ASLWGG RFT VPHLRDTKKT IQFDFQILSK N NNSQSDW 780
SFRLSVEAQA QVTLNGVSKP EAVLFPVSDW HPRDQPQKEE D GPAVHHVY ELINQGPSSI 840
SQGV E SCP QALEGQQ LY VTRVTGLNCT TNHPINPKGL ELDPEGSLHH QQKREAPSRS 900
SASSGPQI K CPEAECFRLR CELGPLHQQE SQS Q HFRV WAKTF QREH QPFS QCEAV 960
YKALKMPYRI LPRQLPQKER QVATAVQWTK AEGSYGVPLW IIILAILFG L GL IYI 1020
YKLGFFKRS PYGTAMEKAQ KPPATSDA
Seq ID NO: 5 DNA sequence
Nucleic Acid Accession #: NM_002211.1
Coding sequence: 1..2397
1 11 21 31 41 51 | 1 | 1 |1 | 1 | 1 I 1 ATGAATTTAC AACCAATTTT CTGGATTGGA CTGATCAGTT CAGTTTGCTG TGTGTTTGCT 60
CAAACAGATG AAAATAGATG TTTAAAAGCA AATGCCAAAT CATGTGGAGA ATGTATACAA 120
GCAGGGCCAA ATTGTGGGTG GTGCACAAAT TCAACATTTT TACAGGAAGG AATGCCTACT 180
TCTGCACGAT GTGATGATTT AGAAGCCTTA AAAAAGAAGG GTTGCCCTCC AGATGACATA 240
GAAAATCCCA GAGGCTCCAA AGATATAAAG AAAAATAAAA ATGTAACCAA CCGTAGCAAA 300
GGAACAGCAG AGAAGCTCAA GCCAGAGGAT ATTACTCAGA TCCAACCACA GCAGTTGGTT 360
TTGCGATTAA GATCAGGGGA GCCACAGACA TTTACATTAA AATTCAAGAG AGCTGAAGAC 420
TATCCCATTG ACCTCTACTA CCTTATGGAC CTGTCTTACT CAATGAAAGA CGATTTGGAG 480
AATGTAAAAA GTCTTGGAAC AGATCTGATG AATGAAATGA GGAGGATTAC TTCGGACTTC 540 AGAATTGGAT TTGGCTCATT TGTGGAAAAG ACTGTGATGC CTTACATTAG CACAACACCA 600 GCTAAGCTCA GGAACCCTTG CACAAGTGAA CAGAACTGCA CCAGCCCATT TAGCTACAAA 660 AATGTGCTCA GTCTTACTAA TAAAGGAGAA GTATTTAATG AACTTGTTGG AAAACAGCGC 720 ATATCTGGAA ATTTGGATTC TCCAGAAGGT GGTTTCGATG CCATCATGCA AGTTGCAGTT 780 TGTGGATCAC TGATTGGCTG GAGGAATGTT ACACGGCTGC TGGTGTTTTC CACAGATGCC 840 GGGTTTCACT TTGCTGGAGA TGGGAAACTT GGTGGCATTG TTTTACCAAA TGATGGACAA 900 TGTCACCTGG AAAATAATAT GTACACAATG AGCCATTATT ATGATTATCC TTCTATTGCT 960 CACCTTGTCC AGAAACTGAG TGAAAATAAT ATTCAGACAA TTTTTGCAGT TACTGAAGAA 1020 TTTCAGCCTG TTTACAAGGA GCTGAAAAAC TTGATCCCTA AGTCAGCAGT AGGAACATTA 1080 TCTGCAAATT CTAGCAATGT AATTCAGTTG ATCATTGATG CATACAATTC CCTTTCCTCA 1140 GAAGTCATTT TGGAAAACGG CAAATTGTCA GAAGGAGTAA CAATAAGTTA CAAATCTTAC 1200 TGCAAGAACG GGGTGAATGG AACAGGGGAA AATGGAAGAA AATGTTCCAA TATTTCCATT 1260 GGAGATGAGG TTCAATTTGA AATTAGCATA ACTTCAAATA AGTGTCCAAA AAAGGATTCT 1320 GACAGCTTTA AAATTAGGCC TCTGGGCTTT ACGGAGGAAG TAGAGGTTAT TCTTCAGTAC 1380 ATCTGTGAAT GTGAATGCCA AAGCGAAGGC ATCCCTGAAA GTCCCAAGTG TCATGAAGGA 1440 AATGGGACAT TTGAGTGTGG CGCGTGCAGG TGCAATGAAG GGCGTGTTGG TAGACATTGT 1500 GAATGCAGCA CAGATGAAGT TAACAGTGAA GACATGGATG CTTACTGCAG GAAAGAAAAC 1560 AGTTCAGAAA TCTGCAGTAA CAATGGAGAG TGCGTCTGCG GACAGTGTGT TTGTAGGAAG 1620 AGGGATAATA CAAATGAAAT TTATTCTGGC AAATTCTGCG AGTGTGATAA TTTCAACTGT 1680 GATAGATCCA ATGGCTTAAT TTGTGGAGGA AATGGTGTTT GCAAGTGTCG TGTGTGTGAG 1740 TGCAACCCCA ACTACACTGG CAGTGCATGT GACTGTTCTT TGGATACTAG TACTTGTGAA 1800 GCCAGCAACG GACAGATCTG CAATGGCCGG GGCATCTGCG AGTGTGGTGT CTGTAAGTGT 1860 ACAGATCCGA AGTTTCAAGG GCAAACGTGT GAGATGTGTC AGACCTGCCT TGGTGTCTGT 1920 GCTGAGCATA AAGAATGTGT TCAGTGCAGA GCCTTCAATA AAGGAGAAAA GAAAGACACA 1980 TGCACACAGG AATGTTCCTA TTTTAACATT ACCAAGGTAG AAAGTCGGGA CAAATTACCC 2040 CAGCCGGTCC AACCTGATCC TGTGTCCCAT TGTAAGGAGA AGGATGTTGA CGACTGTTGG 2100 TTCTATTTTA CGTATTCAGT GAATGGGAAC AACGAGGTCA TGGTTCATGT TGTGGAGAAT 2160 CCAGAGTGTC CCACTGGTCC AGACATCATT CCAATTGTAG CTGGTGTGGT TGCTGGAATT 2220 GTTCTTATTG GCCTTGCATT ACTGCTGATA TGGAAGCTTT TAATGATAAT TCATGACAGA 2280 AGGGAGTTTG CTAAATTTGA AAAGGAGAAA ATGAATGCCA AATGGGACAC GGGTGAAAAT 2340 CCTATTTATA AGAGTGCCGT AACAACTGTG GTCAATCCGA AGTATGAGGG AAAATGA
Seq ID NO: 6 Protein sequence Protein Accession #: NP 002202.1
11 21 31 41 51
I I I I I
MNLQPIFWIG ISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCG CTN STF OEGMPT 60 SARCDD EALi KKKGCPPDDI ENPRGSKDIK KNKNVTNRSK GTAEKLKPED ITQIQPQQLV 120 LR RSGEPQT FT KFKRAED YPIDLYY MD LSYSMKDDLE NVKSLGTDLM NEMRRITSDF 180 RIGFGSFVEK TVMPYISTTP AKLRNPCTSE QNCTSPFSYK NVLSLTNKGE VFNE VGKQR 240 ISGNLDSPEG GFDAIMQVAV CGS IG RNV TRM.VFSTDA GFHFAGDGKL GGIV PNDGQ 300 CHLENNMYTM SHYYDYPSIA H VQKLSENN IQTIFAVTEE FQPVYKELKN IPKSAVGT 360 SANSSNVIQ IIDAYNS SS EVILENGI S EGVTISYKSY CKNGVNGTGE NGRKCSNISI 420 GDEVQFEISI TSNKCPKKDS DSFKIRPLGF TEEVEVX QY ICECECQSEG IPESPKCHEG 480 NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK 540 RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTSTCE 600 ASNGQICNGR GICECGVCKC TDPKFQGQTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDT 660 CTQECSYFNI TKVESRDKLP QPVQPDPVSH CKEKDVDDCW FYFTYSVNGN NEVMVHWEN 720 PECPTGPDII PIVAGWAGI V IGIAL LI WKLLMIIHDR REFAKFEKEK MNAK DTGEN 780 PIYKSAVTTV VNPKYEGK
Seq ID NO: 7 DNA sequence Nucleic Acid Accession #: NM 002425 Coding sequence: 26..1453
60
120
180
Figure imgf000952_0001
240
GGTGACAGGG AAGCTAGACA CTGACACTCT GGAGGTGATG CGCAAGCCCA GGTGTGGAGT 300
TCCTGACGTT GGTCACTTCA GCTCCTTTCC TGGCATGCCG AAGTGGAGGA AAACCCACCT 360
TACATACAGG ATTGTGAATT ATACACCAGA TTTGCCAAGA GATGCTGTTG ATTCTGCCAT 420
TGAGAAAGCT CTGAAAGTCT GGGAAGAGGT GACTCCACTC ACATTCTCCA GGCTGTATGA 480
AGGAGAGGCT GATATAATGA TCTCTTTCGC AGTTAAAGAA CATGGAGACT TTTACTCTTT 540
TGATGGCCCA GGACACAGTT TGGCTCATGC CTACCCACCT GGACCTGGGC TTTATGGAGA 600
TATTCACTTT GATGATGATG AAAAATGGAC AGAAGATGCA TCAGGCACCA ATTTATTCCT 660
CGTTGCTGCT CATGAACTTG GCCACTCCCT GGGGCTCTTT CACTCAGCCA ACACTGAAGC 720
TTTGATGTAC CCACTCTACA ACTCATTCAC AGAGCTCGCC CAGTTCCGCC TTTCGCAAGA 780
TGATGTGAAT GGCATTCAGT CTCTCTACGG ACCTCCCCCT GCCTCTACTG AGGAACCCCT 840
GGTGCCCACA AAATCTGTTC CTTCGGGATC TGAGATGCCA GCCAAGTGTG ATCCTGCTTT 900
GTCCTTCGAT GCCATCAGCA CTCTGAGGGG AGAATATCTG TTCTTTAAAG ACAGATATTT 960
TTGGCGAAGA TCCCACTGGA ACCCTGAACC TGAATTTCAT TTGATTTCTG CATTTTGGCC 1020
CTCTCTTCCA TCATATTTGG ATGCTGCATA TGAAGTTAAC AGCAGGGACA CCGTTTTTAT 1080
TTTTAAAGGA AATGAGTTCT GGGCCATCAG AGGAAATGAG GTACAAGCAG GTTATCCAAG 1140
AGGCATCCAT ACCCTGGGTT TTCCTCCAAC CATAAGGAAA ATTGATGCAG CTGTTTCTGA 1200
CAAGGAAAAG AAGAAAACAT ACTTCTTTGC AGCGGACAAA TACTGGAGAT TTGATGAAAA 1260
TAGCCAGTCC ATGGAGCAAG GCTTCCCTAG ACTAATAGCT GATGACTTTC CAGGAGTTGA 1320
GCCTAAGGTT GATGCTGTAT TACAGGCATT TGGATTTTTC TACTTCTTCA GTGGATCATC 1380
ACAGTTTGAG TTTGACCCCA ATGCCAGGAT GGTGACACAC ATATTAAAGA GTAACAGCTG 1440
GTTACATTGC TAGGCGAGAT AGGGGGAAGA CAGATATGGG TGTTTTTAAT AAATCTAATA 1500
ATTATTCATC TAATGTATTA TGAGCCAAAA TGGTTAATTT TTCCTGCATG TTCTGTGACT 1560 GAAGAAGATG AGCCTTGCAG ATATCTGCAT GTGTCATGAA GAATGTTTCT GGAATTCTTC 1620
ACTTGCTTTT GAATTGCACT GAACAGAATT AAGAAATACT CATGTGCAAT AGGTGAGAGA 1680
ATGTATTTTC ATAGATGTGT TATTACTTCC TCAATAAAAA GTTTTATTTT GGGCCTGTTC 1740 CTT
Seq ID NO: 8 Protein sequence Protein Accession #: NP_002416
1 11 21 31 41 51
MHLAF V C LPVCSAYP S GAAKEEDSNK DLAQQYLEKY YN EKDVKQF RRKDSNLIVK 60
KIQGMQKFLG EVTGK DTD TLEVMRKPRC GVPDVGHFSS FPGMPKWRKT H TYRIVNYT 120
PD PRDAVDS AIEKA KV E EVTP TFSRL YEGEADIMIS FAVKEHGDFY SFDGPGHSLA 180
HAYPPGPGLY GDIHFDDDEK WTEDASGTN FLVAAHELGH S G FHSANT EA MYP YNS 240
FTE AQFR S QDDVNGIQΞ YGPPPASTEE P VPTKSVPS GSEMPAKCDP ALSFDAIST 300
RGEYLFFKDR YF RRSH NP EPEFHLISAF PSLPSY DA AYEVNSRDTV FIFKGNEFWA 360
IRGNEVQAGY PRGIHT GFP PTIRKIDAAV SDKEKKKTYF FAADKYWRFD ENSQSMEQGF 420
PRLIADDFPG VEPKVDAV Q AFGFFYFFSG SSQFEFDPNA RMVTHII.KSN S HC
Seq ID NO: 9 DNA sequence
Nucleic Acid Accession ft: XM_058189.2 Coding sequence: 169..774
11 21 31 41 51
I I I I I
GAAGACCAGC TCAGCTCTTC AGTTGTTGAT CATTGTCTAT TGTTCTCCAA ACAGTAAACC 60 AGTATTTCAC ACTGAGATTG TCGGCTGCGG GTATATTCCA ATTCCCCGTC TCCTCATGAA 120 TATGAAGTGA AGGGCTCTGA CCCTGGAAGT GGTTCTAAGC AGGGCAAAAT GGGGTCTCGG 180 AAGTGTGGAG GCTGCCTAAG TTGTTTGCTG ATTCCGCTTG CACTTTGGAG TATAATCGTG 240 AACATATTAT TGTATTTCCC GAATGGGCAA ACTTCCTATG CATCCAGCAA TAAACTCACC 300 AACTACGTGT GGTATTTTGA AGGAATCTGT TTCTCAGGCA TCATGATGCT TATAGTAACA 360 ACAGTTCTTC TGGTACTGGA GAATAATAAC AACTATAAAT GTTGCCAGAG TGAAAACTGC 420 AGCAAAAAAT ATGTGACACT GCTGTCAATT ATCTTTTCTT CCCTCGGAAT TGCTTTTTCT 480 GGATACTGCC TGGTCATCTC TGCCTTGGGT CTTGTCCAAG GGCCATATTG CCGCACCCTT 540 GATGGCTGGG AGTATGCTTT TGAAGGCACT GCTGGACGTT TCCTTACAGA TTCTAGCATA 600 TGGATTCAGT GCCTGGAACC TGCACATGTT GTGGAGTGGA ACATCATTTT ATTTTCCATT 660 CTCATAACCC TCAGTGGGCT TCAAGTGATC ATCTGCCTCA TCAGAGTAGT CATGCAACTA 720 TCCAAGATAC TGTGTGGAAG CTATTCAGTG ATCTTCCAGC CTGGAATCAT TTGAATAAGG 780 ACAAAATGTT TTCCATTATC AAGACATGGC CATCTATCTA AATATTATAT CAACTGTGTA 840 GACTTGAGGG CAATATTGAA ATGATGGTGC TTTCTGCATT TGGTGTTTAT TTGTAAAAAA 900 TTTGCAGTCC TCACTGCACA TGCAAGTATA CCACCCTTCC ATTTAGTATG TTTTTTAAGT 960 AATATGCATC AGAAACTTCA GAAATACTTC TGCCCTTTGA TCAAACAAAT CCATTTCCAA 1020 GAATCTGTAC TAGGGAAGTA AATAAGAATA TGAGAGAAAC CTTTATGCAA ATATGTATAT 1080 TGCAACATTA TTTAATATTC TGGAAAATTG GAAACACCCC AAAATTCTAA ACTCAGAGGA 1140 AGGATTAAGT AAAGAGTGGT ACATACTGTA AATGTTTTCT GATATTAAAA AAAAAATTAA 1200 ATAAAAAATA AAGAGTACTA CATGGTTGTA AAA
Seq ID NO: 10 Protein sequence Protein Accession ft: XP 058189.1
11 21 31 41 51
I I I I I I
MGSRKCGGCL SCLLIPIiA W SIIVNILLYF PNGQTSYASS NKLTNYVWYF EGICFSGIMM 60 TJIVTTVL VL, ENNNNYKCCQ SENCSKKYVT L SIIFSSLG IAFSGYCLVI SALGLVQGPY 120 CRT DGWEYA FEGTAGRFLT DSSIWIQCLE PAHWEWNII LFSILITLSG QVIIC IRV 180 VMQLSKILCG SYSVIFQPGI I
Seq ID NO: 11 DNA sequence
Nucleic Acid Accession #: NM_002421.2
Coding seguence: 1..1409
60
120
Figure imgf000953_0001
180
GTTGAAAAAT TGAAGCAAAT GCAGGAATTC TTTGGGCTGA AAGTGACTGG GAAACCAGAT 240
GCTGAAACCC TGAAGGTGAT GAAGCAGCCC AGATGTGGAG TGCCTGATGT GGCTCAGTTT 300
GTCCTCACTG AGGGGAACCC TCGCTGGGAG CAAACACATC TGACCTACAG GATTGAAAAT 360
TACACGCCAG ATTTGCCAAG AGCAGATGTG GACCATGCCA TTGAGAAAGC CTTCCAACTC 420
TGGAGTAATG TCACACCTCT GACATTCACC AAGGTCTCTG AGGGTCAAGC AGACATCATG 480
ATATCTTTTG TCAGGGGAGA TCATCGGGAC AACTCTCCTT TTGATGGACC TGGAGGAAAT 540
CTTGCTCATG CTTTTCAACC AGGCCCAGGT ATTGGAGGGG ATGCTCATTT TGATGAAGAT 600
GAAAGGTGGA CCAACAATTT CAGAGAGTAC AACTTACATC GTGTTGCGGC TCATGAACTC 660
GGCCATTCTC TTGGACTCTC CCATTCTACT GATATCGGGG CTTTGATGTA CCCTAGCTAC 720
ACCTTCAGTG GTGATGTTCA GCTAGCTCAG GATGACATTG ATGGCATCCA AGCCATATAT 780
GGACGTTCCC AAAATCCTGT CCAGCCCATC GGCCCACAAA CCCCAAAAGC ATGTGACAGT 840
AAGCTAACCT TTGATGCTAT AACTACGATT CGGGGAGAAG TGATGTTCTT TAAAGACAGA 900
TTCTACATGC GCACAAATCC CTTCTACCCG GAAGTTGAGC TCAATTTCAT TTCTGTTTTC 960
TGGCCACAAC TGCCAAATGG GCTTGAAGCT GCTTACGAAT TTGCCGACAG AGATGAAGTC 1020
CGGTTTTTCA AAGGGAATAA GTACTGGGCT GTTCAGGGAC AGAATGTGCT ACACGGATAC 1080
CCCAAGGACA TCTACAGCTC CTTTGGCTTC CCTAGAACTG TGAAGCATAT CGATGCTGCT 1140
CTTTCTGAGG AAAACACTGG AAAAACCTAC TTCTTTGTTG CTAACAAATA CTGGAGGTAT 1200
GATGAATATA AACGATCTAT GGATCCAGGT TATCCCAAAA TGATAGCACA TGACTTTCCT 1260 GGAATTGGCC ACAAAGTTGA TGCAGTTTTC ATGAAAGATG GATTTTTCTA TTTCTTTCAT 1320 GGAACAAGAC AATACAAATT TGATCCTAAA ACGAAGAGAA TTTTGACTCT CCAGAAAGCT 1380 AATAGCTGGT TCAACTGCAG GAAAAATTAG
Seq ID NO: 12 Protein sequence Protein Accession #: NP_002412.1
1 11 21 31 41 51
I I I I I I
MHSFPPLLLL LFWGWSHSF PAT ETQEQD VD VQKY EK YYNLKNDGRQ VEKRRNSGPV 60
VEKLKQMQEF FG KVTGKPD AETLKVMKQP RCGVPDVAQF V TEGNPR E QTH TYRIEN 120
YTPDLPRADV DHAIEKAFQ WSNVTPLTFT KVSEGQADIM ISFVRGDHRD NSPFDGPGGN 180 AHAFQPGPG IGGDAHFDED ERWTNNFREY NLHRVAAHE GHSLG SHST DIGALMYPSY 240
TFSGDVQLAQ DDIDGIQAIY GRSQNPVQPI GPQTPKACDS KLTFDAITTI RGEVMFFKDR 300
FYMRTNPFYP EVELNFISVF WPQLPNGLEA AYEFADRDEV RFFKGNKYWA VQGQNV HGY 360
PKDIYSSFGF PRTVKHIDAA SEENTGKTY FFVANKY RY DEYKRSMDPG YPKMIAHDFP 420 GIGHKVDAVF MKDGFFYFFH GTRQYKFDPK TKRILTLQKA NSWFNCRKN
Seq ID NO: 13 DNA sequence Nucleic Acid Accession ff: NM 002421.2
Coding sequence: 1..1409
1 11 21 31 41 51
A ITGCACAGCT TITCCTCCACT GICTGCTGCTG CITGTTCTGGG GITGTGGTGTC AICACAGCTTC 60
CCAGCGACTC TAGAAACACA AGAGCAAGAT GTGGACTTAG TCCAGAAATA CCTGGAAAAA 120
TACTACAACC TGAAGAATGA TGGGAGGCAA GTTGAAAAGC GGAGAAATAG TGGCCCAGTG 180
GTTGAAAAAT TGAAGCAAAT GCAGGAATTC TTTGGGCTGA AAGTGACTGG GAAACCAGAT 240
GCTGAAACCC TGAAGGTGAT GAAGCAGCCC AGATGTGGAG TGCCTGATGT GGCTCAGTTT 300
GTCCTCACTG AGGGGAACCC TCGCTGGGAG CAAACACATC TGACCTACAG GATTGAAAAT 360
TACACGCCAG ATTTGCCAAG AGCAGATGTG GACCATGCCA TTGAGAAAGC CTTCCAACTC 420
TGGAGTAATG TCACACCTCT GACATTCACC AAGGTCTCTG AGGGTCAAGC AGACATCATG 480
ATATCTTTTG TCAGGGGAGA TCATCGGGAC AACTCTCCTT TTGATGGACC TGGAGGAAAT 540
CTTGCTCATG CTTTTCAACC AGGCCCAGGT ATTGGAGGGG ATGCTCATTT TGATGAAGAT 600
GAAAGGTGGA CCAACAATTT CAGAGAGTAC AACTTACATC GTGTTGCGGC TCATGCCCTC 660
GGCCATTCTC TTGGACTCTC CCATTCTACT GATATCGGGG CTTTGATGTA CCCTAGCTAC 720
ACCTTCAGTG GTGATGTTCA GCTAGCTCAG GATGACATTG ATGGCATCCA AGCCATATAT 780
GGACGTTCCC AAAATCCTGT CCAGCCCATC GGCCCACAAA CCCCAAAAGC ATGTGACAGT 840
AAGCTAACCT TTGATGCTAT AACTACGATT CGGGGAGAAG TGATGTTCTT TAAAGACAGA 900
TTCTACATGC GCACAAATCC CTTCTACCCG GAAGTTGAGC TCAATTTCAT TTCTGTTTTC 960
TGGCCACAAC TGCCAAATGG GCTTGAAGCT GCTTACGAAT TTGCCGACAG AGATGAAGTC 1020
CGGTTTTTCA AAGGGAATAA GTACTGGGCT GTTCAGGGAC AGAATGTGCT ACACGGATAC 1080
CCCAAGGACA TCTACAGCTC CTTTGGCTTC CCTAGAACTG TGAAGCATAT CGATGCTGCT 1140
CTTTCTGAGG AAAACACTGG AAAAACCTAC TTCTTTGTTG CTAACAAATA CTGGAGGTAT 1200
GATGAATATA AACGATCTAT GGATCCAGGT TATCCCAAAA TGATAGCACA TGACTTTCCT 1260
GGAATTGGCC ACAAAGTTGA TGCAGTTTTC ATGAAAGATG GATTTTTCTA TTTCTTTCAT 1320
GGAACAAGAC AATACAAATT TGATCCTAAA ACGAAGAGAA TTTTGACTCT CCAGAAAGCT 1380 AATAGCTGGT TCAACTGCAG GAAAAATTAG
Seq ID NO: 14 Protein sequence Protein Accession ft: NP 002412.1 1 11 21 31 41 51 I I I I I I
MHSFPPLLLL LFWGWSHSF PATLETQEQD VDLVQKYLEK YYNLKNDGRQ VEKRRNSGPV 60
VEKLKQMQEF FGLKVTGKPD AETLKVMKQP RCGVPDVAQF VLTEGNPRWE QTHLTYRIEN 120
YTPDLPRADV DHAIEKAFQL WSNVTPLTFT KVSEGQADIM ISFVRGDHRD NSPFDGPGGN 180
LAHAFQPGPG IGGDAHFDED ERWTNNFREY NLHRVAAHAL GHSLGLSHST DIGALMYPSY 240
TFSGDVQLAQ DDIDGIQAIY GRSQNPVQPI GPQTPKACDS KLTFDAITTI RGEVMFFKDR 300
FYMRTNPFYP EVELNFISVF WPQLPNGLEA AYEFADRDEV RFFKGNKYWA VQGQNVLHGY 360
PKDIYSSFGF PRTVKHIDAA LSEENTGKTY FFVANKYWRY DEYKRSMDPG YPKMIAHDFP 420 GIGHKVDAVF MKDGFFYFFH GTRQYKFDPK TKRILTLQKA NSWFNCRKN
Seq ID NO: 15 DNA sequence
Nucleic Acid Accession #: FGENESH predicted
Coding sequence: 141..1580
1 11 21 31 41 51
I I I I i I
TCTGCGTGTG CCGGGGCTAG GGGCTGGAAG TCCTGGCTCT AGTTGCACCT CGGAAGGAAA 60
AGGCAAACAG AGGAGGGAAG GCGTCTTAGG ACTGCCTGGA TCCAGAGCAC TTTCCTCGGC 120
CTCTACAGGC CTGTGTCGCT ATGGGTTCCC CCGCCGCCCC GGAGGGAGCG CTGGGCTACG 180
TCCGCGAGTT CACTCGCCAC TCCTCCGACG TGCTGGGCAA CCTCAACGAG CTGCGCCTGC 240
GCGGGATCCT CACTGACGTC ACGCTGCTGG TTGGCGGGCA ACCCCTCAGA GCACACAS.GG 300
CAGTTCTCAT CGCCTGCAGT GGCTTCTTCT ATTCAATTTT CCGGGGCCGT GCGGGAGTCG 360
GGGTGGACGT GCTCTCTCTG CCCGGGGGTC CCGAAGCGAG AGGCTTCGCC CCTCTATTGG 420
ACTTCATGTA CACTTCGCGC CTGCGCCTCT CTCCAGCCAC TGCACCAGCA GTCCTAGCGG 480
CCGCCACCTA TTTGCAGATG GAGCACGTGG TCCAGGCATG CCACCGCTTC ATCCAGGCCA 540
GCTATGAACC TCTGGGCATC TCCCTGCGCC CCCTGGAAGC AGAACCCCCA ACACCCCCAA 600
CGGCCCCTCC ACCAGGTAGT CCCAGGCGCT CCGAAGGACA CCCAGACCCA CCTACTGAAT 660
CTCGAAGCTG CAGTCAAGGC CCCCCCAGTC CAGCCAGCCC TGACCCCAAG GCCTGCAACT 720
GGAAAAAGTA CAAGTACATC GTGCTAAACT CTCAGGCCTC CCAAGCAGGG AGCCTGGTCG 780 GGGAGAGAAG TTCTGGTCAA CCTTGCCCCC AAGCCAGGCT CCCCAGTGGA GACGAGGCCT 840
CCAGCAGCAG CAGCAGCAGC AGCAGCAGCA GTGAAGAAGG ACCCATTCCT GGTCCCCAGA 900
GCAGGCTCTC TCCAACTGCT GCCACTGTGC AGTTCAAATG TGGGGCTCCA GCCAGTACCC 960
CCTACCTCCT CACATCCCAG GCTCAAGACA CCTCTGGATC ACCCTCTGAA CGGGCTCGTC 1020
CACTACCGGG AAGTGAATTT TTCAGCTGCC AGAACTGTGA GGCTGTGGCA GGGTGCTCAT 1080
CGGGGCTGGA CTCCTTGGTT CCTGGGGACG AAGACAAACC CTATAAGTGT CAGCTGTGCC 1140
GGTCTTCGTT CCGCTACAAG GGCAACCTTG CCAGTCATCG TACAGTGCAC ACAGGGGAAA 1200
AGCCTTACCA CTGCTCAATC TGCGGAGCCC GTTTTAACCG GCCAGCAAAC CTGAAAACGC 1260
ACAGCCGCAT CCATTCGGGA GAGAAGCCGT ATAAGTGTGA GACGTGCGGC TCGCGCTTTG 1320 0 TACAGGTGGC ACATCTGCGG GCGCACGTGC TGATCCACAC CGGGGAGAAG CCCTACCCTT 1380
GCCCTACCTG CGGAACCCGC TTCCGCCACC TGCAGACCCT CAAGAGCCAC GTTCGCATCC 1440
ACACCGGAGA GAAGCCTTAC CACTGCGACC CCTGTGGCCT GCATTTCCGG CACAAGAGTC 1500
AACTGCGGCT GCATCTGCGC CAGAAACACG GAGCTGCTAC CAACACCAAA GTGCACTACC 1560
ACATTCTCGG GGGGCCCTAG CTGAGCGCAG GCCCAGGCCC CACTTGCTTC CTGCGGGTGG 1620 5 GAAAGCTGCA GGCCCAGGCC TTGCTTCCCT ATCAGGCTTG GGCATAGGGG TGTGCCAGGC 1680
CACTTTGGTA TCAGAAATTG CCACCCTCTT AATTTCTCAC TGGGGAGAGC AGGGGTGGCA 1740
GATCCTGGCT AGATCTGCCT CTGTTTTGCT GGTCAAAACC TCTTCCCCAC AAGCCAGATT 1800
GTTTCTGAGG AGAGAGCTAG CTAGGGGCTG GGAAAGGGGA GAGATTGGAG TCCTGGTCTC 1860
CCTAAGGGAA TAGCCCTCCA CCTGTGGCCC CCATTGCATT CAGTTTATCT GTAAATATAA 1920 0 TTTATTGAGG CCTTTGGGTG GCACCGGGGC CTTCATTCGA TTGCATTTCC CACTCCCCTC 1980
TTCCACAAGT GTGATTAAAA GTGACCAGAA ACACAGAAGG TGAGATCACA GCTCTGCTGG 2040
CAGAGATTAC TAGCCCTTGG CTCTCTCGTT TGGCTTGGGT ATTTTATATT ATTTCTGTCA 2100
TAACTTTTAT CTTTAGAATT GTTCTTTCTC CTGTTTGTTT GCTTGTTAGT TTGTTTAAAA 2160
TGGAAAAAGG GGTTCTCTGT GTTCTGCCCC TGTAATTCTA GGTCTGGAAC CTTTATTTGT 2220 5 TCTAGGGCAG CTCTGGGAAC ATGCGGGATT GTGGAATTGG GTCAGGAACC CTCTCTGGTA 2280
TTCTGGATGT TGTAGGTTCT CTAGCAGTCT AGAAATGGAT ACAGACATTT CTCTGTTCTT 2340
CAAGGGTGAT AGGAACCATT ATGTTGAGCC CAAAATGGAA GTAATAATAA ATGCCTCCTG 2400
GAGGCTGTGG GTGTGGGGGA TTCTGTATCT GGATTCCGTA TCACTCCAAC TGGAGGCTGT 2460
GGGTGTGGGG GATTCTGTAT CTGGATTCCG TATCACTCCA AGTGGAGGCT GGCAGGTTTT 2520 0 TCTGCAAGAT GGTCCAGAAT CTAAAATGTC CCATTAATCT GGTCACTTGG GTTTGGCTCT 2580
GCTGTATCCA TCTATAGTGG TAGAGACCCA CCAGGGCTCA AGTGGAGTCC ATCATCCTCC 2640
CACGGGGGCC TGTTCTTAGC ACTGAGTTGA TCGCTCCATG GGGGAGAGAT CAGACATTCC 2700
TTATCAGAGA TGATGTGACC TTTTCTGACT CTGCCCAGTC TCTATGAATG TTATGGCCTA 2760
GGGAAGAATC ATGAAACTCT TTAGCTTGAT TAGATGGTAA ACAGTGTTAA CCCATCCTTT 2820 5 ACTACAGAGG CATATGGGTT TGAATGTTAC CTGGGGTTCT CTCTATTGAG TTGAGCCCCT 2880
TCTTCCTTTA GTGGGTTTTG GACATCTTCT GGCAAGTGTC CAGATGCCAG AACCTTCTTT 2940
TCCTCTAGAA GGGATGGTGC TTGGTAACCT TACCTTTTAA AAGCTGGGTC TGTGACCTGG 3000
TCTTCCCATC CCTGCATTCC TGTCTGGAAC CAGTGAATGC ATTAGAACCT TCCATAGGAA 3060
AAGAAAAGGG GCTGAGTTCC ATTCTGGGTT TGCTGTAGTT TGGTTGGGAT TATTGTTGGC 3120 0 ATTACAGATG TAAAAGATTG ACTAGCCCAT AGGCCAAAGG CCTGTTCTAG TTGACCAAGT 3180
TTCAAGTAGG ATTAAGAGGT TGGTTGAGGG GTGCAGTTTC TGGTGTAGGC CAGGTAGGTA 3240
GAAAGTGAGG AACAGGGTTG CCTCTTGGCT GGGTGGAGTC TCTGAAATGT TAGAAGAAGC 3300
GCTGAAGCCT TGATTGATAG TTCTGCCCCT TGTTGCCCTG GGGCTTATCT GATTATGGGA 3360
CGAGGGTAGA AAGTAAGAAG CACTTTTGAA TTTGTGGGGT AGAACTTCAA CAATAAGTCA 3420 5 GTTCTAGTGG CTGTCGCCTG GGGACTAGTG AGAAAGCTAC TCTTCTCCCT CTTCCCTCTT 3480
TCTCCCCATG GCCCCACTGC AGAATTAAAG AAGGAAGAAG GGAAGGCGGA GGAGTCTATA 3540
AGAAGGAATC ATGATTTCTA TTTAGCAGAT TGGATGGGCA GGTGGAGAAT GCCTGGGGGT 3600
AGAAATGTTA GATCTTGCAA CATCAGATCC TTGGAATAAA GAAGCCTCTC TGYGCWRAAA 3660 AAAAAAAAAA AAAAAA 0
Seq ID NO: 16 Protein sequence Protein Accession ft: FGENESH predicted
__ 1 11 21 31 41 51 5 i i i i i i
MGSPAAPEGA LGYVREFTRH SSDVLGNLNE LRLRGILTDV TLLVGGQPLR AHKAVLIACS 60
GFFYSIFRGR AGVGVDVLSL PGGPEARGFA PLLDFMYTSR LRLSPATAPA VLAAATYLQM 120
EHWQACHRF IQASYEPLGI SLRPLEAEPP TPPTAPPPGS PRRSEGHPDP PTESRSCSQG 180
PPΞPASPDPK ACNWKKYKYI VLNSQASQAG SLVGERSSGQ PCPQARLPSG DEASSSSSSS 240
60 SSSSEEGPIP GPQSRLSPTA ATVQFKCGAP ASTPYLLTSQ AQDTSGSPSE RARPLPGSEF 300
FSCQNCEAVA GCSSGLDSLV PGDEDKPYKC QLCRSSFRYK GNLASHRTVH TGEKPYHCSI 360
CGARFNRPAN LKTHSRIHSG EKPYKCETCG SRFVQVAHLR AHVLIHTGEK PYPCPTCGTR 420 FRHLQTLKSH VRIHTGEKPY HCDPCGLHFR HKSQLRLHLR QKHGAATNTK VHYHILGGP
65 Seq ID NO: 17 DNA sequence
Nucleic Acid Accession #: XM_039209 Coding sequence: 1..2049
_. 1 11 21 31 41 51
70 i i i i i i
ATGCTGAAGA TGCTCTCCTT TAAGCTGCTG CTGCTGGCCG TGGCTCTGGG CTTCTTTGAA 60
GGAGATGCTA AGTTTGGGGA AAGAAACGAA GGGAGCGGAG CAAGGAGGAG AAGGTGCCTG 120
AATGGGAACC CCCCGAAGCG CCTGAAAAGG AGAGACAGGA GGATGATGTC CCAGCTGGAG 180
CTGCTGAGTG GGGGAGAGAT GCTGTGCGGT GGCTTCTACC CTCGGCTGTC CTGCTGCCTG 240
75 CGGAGTGACA GCCCGGGGCT AGGGCGCCTG GAGAATAAGA TATTTTCTGT TACCAACAAC 300
ACAGAATGTG GGAAGTTACT GGAGGAAATC AAATGTGCAC TTTGCTCTCC ACATTCTCAA 360
AGCCTGTTCC ACTCACCTGA GAGAGAAGTC TTGGAAAGAG ACCTAGTACT TCCTCTGCTC 420
TGCAAAGACT ATTGCAAAGA ATTCTTTTAC ACTTGCCGAG GCCATATTCC AGGTTTCCTT 480
CAAACAACTG CGGATGAGTT TTGCTTTTAC TATGCAAGAA AAGATGGTGG GTTGTGCTTT 540
80 CCAGATTTTC CAAGAAAACA AGTCAGAGGA CCAGCATCTA ACTACTTGGA CCAGATGGAA 600
GAATATGACA AAGTGGAAGA GATCAGCAGA AAGCACAAAC ACAACTGCTT CTGTATTCAG 660
GAGGTTGTGA GTGGGCTGCG GCAGCCCGTT GGTGCCCTGC ATAGTGGGGA TGGCTCGCAA 720
CGTCTCTTCA TTCTGGAAAA AGAAGGTTAT GTGAAGATAC TTACCCCTGA AGGAGAAATT 780
TTCAAGGAGC CTTATTTGGA CATTCACAAA CTTGTTCAAA GTGGAATAAA GGGAGGAGAT 840 GAAAGAGGAC TGCTAAGCCT CGCATTCCAT CCCAATTACA AGAAAAATGG AAAGTTGTAT 900 GTGTCCTATA CCACCAACCA AGAACGGTGG GCTATCGGGC CTCATGACCA CATTCTTAGG 960 GTTGTGGAAT ACACAGTATC CAGAAAAAAT CCACACCAAG TTGATTTGAG AACAGCCAGA 1020 GTCTTTCTTG AAGTTGCAGA ACTCCACAGA AAGCATCTGG GAGGACAACT GCTCTTTGGC 1080 CCTGACGGCT TTTTGTACAT CATTCTTGGT GATGGGATGA TTACACTGGA TGATATGGAA 1140 GAAATGGATG GGTTAAGTGA TTTCACAGGC TCAGTGCTAC GGCTGGATGT GGACACAGAC 1200 ATGTGTAACG TGCCTTATTC CATACCAAGG AGCAACCCAC ACTTCAACAG CACCAACCAG 1260 CCCCCCGAAG TGTTTGCTCA TGGGCTCCAC GATCCAGGCA GATGTGCTGT GGATAGACAT 1320 CCCACTGATA TAAACATCAA TTTAACGATA CTGTGTTCAG ACTCCAATGG AAAAAACAGA 1380 TCATCAGCCA GAATTCTACA GATAATAAAG GGGAAAGATT ATGAAAGTGA GCCATCACTT 1440 TTAGAATTCA AGCCATTCAG TAATGGTCCT TTGGTTGGTG GATTTGTATA CCGGGGCTGC 1500 CAGTCAGAAA GATTGTATGG AAGCTACGTG TTTGGAGATC GTAATGGGAA TTTCCTAACT 1560 CTCCAGCAAA GTCCTGTGAC AAAGCAGTGG CAAGAAAAAC CACTCTGTCT CGGCACTAGT 1620 GGGTCCTGTA GAGGCTACTT TTCCGGTCAC ATCTTGGGAT TTGGAGAAGA TGAACTAGGT 16B0 GAAGTTTACA TTTTATCAAG CAGTAAAAGT ATGACCCAGA CTCACAATGG AAAACTCTAC 1740 AAAATTGTAG ATCCCAAAAG ACCTTTAATG CCTGAGGAAT GCAGAGCCAC GGTACAACCT 1800 GCACAGACAC TGACTTCAGA GTGCTCCAGG CTCTGTCGAA ACGGCTACTG CACCCCCACG 1860 GGAAAGTGCT GCTGCAGTCC AGGCTGGGAG GGGGACTTCT GCAGAACTGC AAAATGTGAG 1920 CCAGCATGTC GTCATGGAGG TGTCTGTGTT AGACCGAACA AGTGCCTCTG TAAAAAAGGA 1980 TATCTTGGTC CTCAATGTGA ACAAGTGGAC AGAAACATCC GCAGAGTGAC CAGGGCAGAC 2040 ATCACCTAG
Seq ID NO: 18 Protein sequence Protein Accession #: XP 039209
11 21 31 41 51
I I I I I
MLKMLSFKLL LLAVALGFFE GDAKFGERNE GSGARRRRCL NGNPPKRLKR RDRRMMSQLE 60 LLSGGEMLCG GFYPRLSCCL RSDSPGLGRL ENKIFSVTNN TECGKLLEEI KCALCSPHSQ 120 SLFHSPEREV LERDLVLPLL CKDYCKEFFY TCRGHIPGFL QTTADEFCFY YARKDGGLCF 180 PDFPRKQVRG PASNYLDQME EYDKVEEISR KHKHNCFCIQ EWSGLRQPV GALHSGDGSQ 240 RLFILEKEGY VKILTPEGEI FKEPYLDIHK LVQSGIKGGD ERGLLSLAFH PNYKKNGKLY 300 VSYTTNQERW AIGPHDHILR WEYTVSRKN PHQVDLRTAR VFLEVAELHR KHLGGQLLFG 360 PDGFLYIILG DGMITLDDME EMDGLSDFTG SVLRLDVDTD MCNVPYSIPR SNPHFNSTNQ 420 PPEVFAHGLH DPGRCAVDRH PTDININLTI LCSDSNGKNR SSARILQIIK GKDYESEPSL 480 LEFKPFSNGP LVGGFVYRGC QSERLYGSYV FGDRNGNFLT LQQSPVTKQW QEKPLCLGTS 540 GSCRGYFSGH ILGFGEDELG EVYILSSSKS MTQTHNGKLY KIVDPKRPLM PEECRATVQP 600 AQTLTSECSR LCRNGYCTPT GKCCCSPGWE GDFCRTAKCE PACRHGGVCV RPNKCLCKKG 660 YLGPQCEQVD RNIRRVTRAD IT
Seq ID NO: 19 DNA sequence
Nucleic Acid Accession ft: NM_014331.2
Coding sequence: 1..1506
11 21 31 41 51
I I I I I
ATGGTCAGAA AGCCTGTTGT GTCCACCATC TCCAAAGGAG GTTACCTGCA GGGAAATGTT 60
AACGGGAGGC TGCCTTCCCT GGGCAACAAG GAGCCACCTG GGCAGGAGAA AGTGCAGCTG 120
AAGAGGAAAG TCACTTTACT GAGGGGAGTC TCCATTATCA TTGGCACCAT CATTGGAGCA 180
GGAATCTTCA TCTCTCCTAA GGGCGTGCTC CAGAACACGG GCAGCGTGGG CATGTCTCTG 240
ACCATCTGGA CGGTGTGTGG GGTCCTGTCA CTATTTGGAG CTTTGTCTTA TGCTGAATTG 300
GGAACAACTA TAAAGAAATC TGGAGGTCAT TACACATATA TTTTGGAAGT CTTTGGTCCA 360
TTACCAGCTT TTGTACGAGT CTGGGTGGAA CTCCTCATAA TACGCCCTGC AGCTACTGCT 420
GTGATATCCC TGGCATTTGG ACGCTACATT CTGGAACCAT TTTTTATTCA ATGTGAAATC 480
CCTGAACTTG CGATCAAGCT CATTACAGCT GTGGGCATAA CTGTAGTGAT GGTCCTAAAT 540
AGCATGAGTG TCAGCTGGAG CGCCCGGATC CAGATTTTCT TAACCTTTTG CAAGCTCACA 600
GCAATTCTGA TAATTATAGT CCCTGGAGTT ATGCAGCTAA TTAAAGGTCA AACGCAGAAC 660
TTTAAAGACG CGTTTTCAGG AAGAGATTCA AGTATTACGC GGTTGCCACT GGCTTTTTAT 720
TATGGAATGT ATGCATATGC TGGCTGGTTT TACCTCAACT TTGTTACTGA AGAAGTAGAA 780
AACCCTGAAA AAACCATTCC CCTTGCAATA TGTATATCCA TGGCCATTGT CACCATTGGC 840
TATGTGCTGA CAAATGTGGC CTACTTTACG ACCATTAATG CTGAGGAGCT GCTGCTTTCA 900
AATGCAGTGG CAGTGACCTT TTCTGAGCGG CTACTGGGAA ATTTCTCATT AGCAGTTCCG 960
ATCTTTGTTG CCCTCTCCTG CTTTGGCTCC ATGAACGGTG GTGTGTTTGC TGTCTCCAGG 1020
TTATTCTATG TTGCGTCTCG AGAGGGTCAC CTTCCAGAAA TCCTCTCCAT GATTCATGTC 1080
CGCAAGCACA CTCCTCTACC AGCTGTTATT GTTTTGCACC CTTTGACAAT GATAATGCTC 1140
TTCTCTGGAG ACCTCGACAG TCTTTTGAAT TTCCTCAGTT TTGCCAGGTG GCTTTTTATT 1200
GGGCTGGCAG TTGCTGGGCT GATTTATCTT CGATACAAAT GCCCAGATAT GCATCGTCCT 1260
TTCAAGGTGC CACTGTTCAT CCCAGCTTTG TTTTCCTTCA CATGCCTCTT CATGGTTGCC 1320
CTTTCCCTCT ATTCGGACCC ATTTAGTACA GGGATTGGCT TCGTCATCAC TCTGACTGGA 1380
GTCCCTGCGT ATTATCTCTT TATTATATGG GACAAGAAAC CCAGGTGGTT TAGAATAATG 1440
TCAGAGAAAA TAACCAGAAC ATTACAAATA ATACTGGAAG TTGTACCAGA AGAAGATAAG 1500
TTATGAACTA ATGGACTTGA GATCTTGGCA ATCTGCCCAA GGGGAGACAC AAAATAGGGA 1560
TTTTTACTTC ATTTTCTGAA AGTCTAGAGA ATTACAACTT TGGTGATAAA CAAAAGGAGT 1620
CAGTTATTTT TATTCATATA TTTTAGCATA TTCGAACTAA TTTCTAAGAA ATTTAGTTAT 1680
AACTCTATGT AGTTATAGAA AGTGAATATG CAGTTATTCT ATGAGTCGCA CAATTCTTGA 1740
GTCTCTGATA CCTACCTATT GGGGTTAGGA GAAAAGACTA GACAATTACT ATGTGGTCAT 1800
TCTCTACAAC ATATGTTAGC ACGGCAAAGA ACCTTCAAAT TGAAGACTGA GATTTTTCTG 1860
TATATATGGG TTTTGTAAAG ATGGTTTTAC ACACTACAGA TGTCTATACT GTGAAAAGTG 1920
TTTTCAATTC TGAAAAAAAG CATACATCAT GATTATGGCA AAGAGGAGAG AAAGAAATTT 1980
ATTTTACATT GACATTGCAT TGCTTCCCCT TAGATACCAA TTTAGATAAC AAACACTCAT 2040
GCTTTAATGG ATTATACCCA GAGCACTTTG AACAAAGGTC AGTGGGGATT GTTGAATACA 2100
TTAAAGAAGA GTTTCTAGGG GCTACTGTTT ATGAGACACA TCCAGGAGTT ATGTTTAAGT 2160
AAAAATCCTT GAGAATTTAT TATGTCAGAT GTTTTTTCAT TCATTATCAG GAAGTTTTAG 2220 TTATCTGTCA TCACATCAGT TTGATCAGGA AAGTGTATAA CACATCTTAG 2280 AGCAAGAGTT AGTTTGGTAT TAAATCCTCA TTAGAACAAC CACCTGTTTC ACTAATAACT 2340 TACCCCTGAT GAGTCTATCT AAACATATGC ATTTTAAGCC TTCAAATTAC ATTATCAACA 2400 TGAGAGAAAT AACCAACAAA GAAGATGTTC AAAATAATAG TCCCATATCT GTAATCATAT 2460 CTACATGCAA TGTTAGTAAT TCTGAAGTTT TTTAAATTTA TGGCTATTTT TACACGATGA 2520 TGAATTTTGA CAGTTTGTGC ATTTTCTTTA TACATTTTAT ATTCTTCTGT TAAAATATCT 2580 CTTCAGATGA AACTGTCCAG ATTAATTAGG AAAAGGCATA TATTAACATA AAAATTGCAA 2640 AAGAAATGTC GCTGTAAATA AGATTTACAA CTGATGTTTC TAGAAAATTT CCACTTCTAT 2700 ATCTAGGCTT TGTCAGTAAT TTCCACACCT TAATTATCAT TCAACTTGCA AAAGAGACAA 2760 CTGATAAGAA GAAAATTGAA ATGAGAATCT GTGGATAAGT GTTTGTGTTC AGAAGATGTT 2820 GTTTTGCCAG TATTAGAAAA TACTGTGAGC CGGGCATGGT GGCTTACATC TGTAATCCCA 2880 GCACTTTGGG AGGCTGAGGG GGTGGATCAC CTGAGGTCGG GAGTTCTAGA CCAGCCTGAC 2940 CAACATGGAG AAACCCCATC TCTACTAAAA ATACAAAATT AGCTGGGCAT GGTGGCACAT 3000 GCTGGTAATC TCAGCTATTG AGGAGGCTGA GGCAGGAGAA TTGCTTGAAC CCGGGAGGCG 3060 GAGGTTGCAG TGAGCCAAGA TTGCACCACT GTACTCCAGC CTGGGTGACA AAGTCAGACT 3120 CCATCTCCAA AAAAAAAAAA AAAA
Seq ID NO: 20 Protein sequence Protein Accession #: NP 055146.1
MVRKPWSTI SKGGYLQGNV NGRLPSLGNK EPPGQEKVQL KRKVTLLRGV SIIIGTIIGA 60
GIFISPKGVL QNTGSVGMSL TIWTVCGVLS LFGALSYAEL GTTIKKSGGH YTYILEVFGP 120
LPAFVRVWVE LLIIRPAATA VISLAFGRYI LEPFFIQCEI PELAIKLITA VGITWMVLN 180
SMSVSWSARI QIFLTFCKLT AILIIIVPGV MQLIKGQTQN FKDAFSGRDS SITRLPLAFY 240
YGMYAYAGWF YLNFVTEEVE NPEKTIPLAI CISMAITIGV YVLTNVAYFT TINAEELLLS 300
NAVAVTFSER LLGNFSLAVP IFVALSCFGS MNGGVFAVSR LFYVASREGH LPEILSMIHV 360
RKHTPLPAVI VLHPLTMIML FSGDLDSLLN FLSFARWLFI GLAVAGLIYL RYKCPDMHRP 420
FKVPLFIPAL FSFTCLFMVA LSLYSDPFST GIGFVITLTG VPAYYLFIIW DKKPRWFRIM 480
SEKITRTLQI I EWPEEDK L
Seq ID NO: 21 DNA sequence Nucleic Acid Accession ft: NM_002422.2 Coding sequence: 64..1497
11 21 31
ACAAGGAGGC AGGCAAGACA GCAAGGCATA GAGACAACAT AGAGCTAAGT AAAGCCAGTG 60
GAAATGAAGA GTCTTCCAAT CCTACTGTTG CTGTGCGTGG CAGTTTGCTC AGCCTATCCA 120
TTGGATGGAG CTGCAAGGGG TGAGGACACC AGCATGAACC TTGTTCAGAA ATATCTAGAA 180
AACTACTACG ACCTCAAAAA AGATGTGAAA CAGTTTGTTA GGAGAAAGGA CAGTGGTCCT 240
GTTGTTAAAA AAATCCGAGA AATGCAGAAG TTCCTTGGAT TGGAGGTGAC GGGGAAGCTG 300
GACTCCGACA CTCTGGAGGT GATGCGCAAG CCCAGGTGTG GAGTTCCTGA TGTTGGTCAC 360
TTCAGAACCT TTCCTGGCAT CCCGAAGTGG AGGAAAACCC ACCTTACATA CAGGATTGTG 420
AATTATACAC CAGATTTGCC AAAAGATGCT GTTGATTCTG CTGTTGAGAA AGCTCTGAAA 480
GTCTGGGAAG AGGTGACTCC ACTCACATTC TCCAGGCTGT ATGAAGGAGA GGCTGATATA 540
ATGATCTCTT TTGCAGTTAG AGAACATGGA GACTTTTACC CTTTTGATGG ACCTGGAAAT 600
GTTTTGGCCC ATGCCTATGC CCCTGGGCCA GGGATTAATG GAGATGCCCA CTTTGATGAT 660
GATGAACAAT GGACAAAGGA TACAACAGGG ACCAATTTAT TTCTCGTTGC TGCTCATGAA 720
ATTGGCCACT CCCTGGGTCT CTTTCACTCA GCCAACACTG AAGCTTTGAT GTACCCACTC 780
TATCACTCAC TCACAGACCT GACTCGGTTC CGCCTGTCTC AAGATGATAT AAATGGCATT 840
CAGTCCCTCT ATGGACCTCC CCCTGACTCC CCTGAGACCC CCCTGGTACC CACGGAACCT 900
GTCCCTCCAG AACCTGGGAC GCCAGCCAAC TGTGATCCTG CTTTGTCCTT TGATGCTGTC 960
AGCACTCTGA GGGGAGAAAT CCTGATCTTT AAAGACAGGC ACTTTTGGCG CAAATCCCTC 1020
AGGAAGCTTG AACCTGAATT GCATTTGATC TCTTCATTTT GGCCATCTCT TCCTTCAGGC 1080
GTGGATGCCG CATATGAAGT TACTAGCAAG GACCTCGTTT TCATTTTTAA AGGAAATCAA 1140
TTCTGGGCCA TCAGAGGAAA TGAGGTACGA GCTGGATACC CAAGAGGCAT CCACACCCTA 1200
GGTTTCCCTC CAACCGTGAG GAAAATCGAT GCAGCCATTT CTGATAAGGA AAAGAACAAA 1260
ACATATTTCT TTGTAGAGGA CAAATACTGG AGATTTGATG AGAAGAGAAA TTCCATGGAG 1320
CCAGGCTTTC CCAAGCAAAT AGCTGAAGAC TTTCCAGGGA TTGACTCAAA GATTGATGCT 1380
GTTTTTGAAG AATTTGGGTT CTTTTATTTC TTTACTGGAT CTTCACAGTT GGAGTTTGAC 1440
CCAAATGCAA AGAAAGTGAC ACACACTTTG AAGAGTAACA GCTGGCTTAA TTGTTGAAAG 1500
AGATATGTAG AAGGCACAAT ATGGGCACTT TAAATGAAGC TAATAATTCT TCACCTAAGT 1560
CTCTGTGAAT TGAAATGTTC GTTTTCTCCT GCCTGTGCTG TGACTCGAGT CACACTCAAG 1620
GGAACTTGAG CGTGAATCTG TATCTTGCCG GTCATTTTTA TGTTATTACA GGGCATTCAA 1680
ATGGGCTGCT GCTTAGCTTG CACCTTGTCA CATAGAGTGA TCTTTCCCAA GAGAAGGGGA 1740
AGCACTCGTG TGCAACAGAC AAGTGACTGT ATCTGTGTAG ACTATTTGCT TATTTAATAA 1800
AGACGATTTG TCAGTTGTTT T
Seq ID NO: 22 Protein sequence
Protein Accession ft: NP_002413
1 11 21 31 41 51 1 1 11 11 1 1 I 1 MKSLPILLLL CVAVCSAYPL DGAARGEDTS MNLVQKYLEN YYDLEKDVKQ FVRRKDSGPV 60
VKKIREMQKF LGLEVTGKLD SDTLEVMRKP RCGVPDVGHF RTFPGIPKWR KTHLTYRIVN 120
YTPDLPKDAV DSAVEKALKV WEEVTPLTFS RLYEGEADIM ISFAVREHGD FYPFDGPGNV 180
LAHAYAPGPG INGDAHFDDD EQWTKDTTGT NLFLVAAHEI GHSLGLFHSA NTEALMYPLY 240
HSLTDLTRFR LSQDDINGIQ SLYGPPPDSP ETPLVPTEPV PPEPGTPANC DPALSFDAVS 300
TLRGEILIFK DRHFWRKSLR KLEPELHLIS SFWPSLPSGV DAAYEVTSKD LVFIFKGNQF 360
WAIRGNEVRA GYPRGIHTLG FPPTVRKIDA AISDKEKNKT YFFVEDKYWR FDEKRNSMEP 420
GFPKQIAEDF PGIDSKIDAV FEEFGFFYFF TGSSQLEFDP NAKKVTHTLK SNSWLNC Seq ID NO: 23 DNA sequence
Nucleic Acid Accession #: NM_006528
Coding sequence : 57..764
11 21 31 41 51
I I I I I
GCCGCCAGCG GCTTTCTCGG ACGCCTTGCC CAGCGGGCCG CCCGACCCCC TGCACCATGG 60 ACCCCGCTCG CCCCCTGGGG CTGTCGATTC TGCTGCTTTT CCTGACGGAG GCTGCACTGG 120 GCGATGCTGC TCAGGAGCCA ACAGGAAATA ACGCGGAGAT CTGTCTCCTG CCCCTAGACT 180 ACGGACCCTG CCGGGCCCTA CTTCTCCGTT ACTACTACGA CAGGTACACG CAGAGCTGCC 240 GCCAGTTCCT GTACGGGGGC TGCGAGGGCA ACGCCAACAA TTTCTACACC TGGGAGGCTT 300 GCGACGATGC TTGCTGGAGG ATAGAAAAAG TTCCCAAAGT TTGCCGGCTG CAAGTGAGTG 360 TGGACGACCA GTGTGAGGGG TCCACAGAAA AGTATTTCTT TAATCTAAGT TCCATGACAT 420 GTGAAAAATT CTTTTCCGGT GGGTGTCACC GGAACCGGAT TGAGAACAGG TTTCCAGATG 480 AAGCTACTTG TATGGGCTTC TGCGCACCAA AGAAAATTCC ATCATTTTGC TACAGTCCAA 540 AAGATGAGGG ACTGTGCTCT GCCAATGTGA CTCGCTATTA TTTTAATCCA AGATACAGAA 600 CCTGTGATGC TTTCACCTAT ACTGGCTGTG GAGGGAATGA CAATAACTTT GTTAGCAGGG 660 AGGATTGCAA ACGTGCATGT GCAAAAGCTT TGAAAAAGAA AAAGAAGATG CCAAAGCTTC 720 GCTTTGCCAG TAGAATCCGG AAAATTCGGA AGAAGCAATT TTAAACATTC TTAATATGTC 780 ATCTTGTTTG TCTTTATGGC TTATTTGCCT TTATGGTTGT ATCTGAAGAA TAATATGACA 840 GCATGAGGAA ACAAATCATT GGTGATTTAT TCACCAGTTT TTATTAATAC AAGTCACTTT 900 TTCAAAAATT TGGATTTTTT TATATATAAC TAGCTGCTAT TCAAATGTGA GTCTACCATT 960 TTTAATTTAT GGTTCAACTG TTTGTGAGAC GAATTCTTGC AATGCATAAG ATATAAAAGC 1020 AAATATGACT CACTCATTTC TTGGGGTCGT ATTCCTGATT TCAGAAGAGG ATCATAACTG 1080 AAACAACATA AGACAATATA ATCATGTGCT TTTAACATAT TTGAGAATAA AAAGGACTAG 1140 CC
Seq ID NO: 24 Protein sequence Protein Accession ft: NP 006519
1 11 21 31 41 51 l l l l l !
MDPARPLGLS ILLLFLTEAA LGDAAQEPTG NNAEICLLPL DYGPCRALLL RYYYDRYTQS 60 CRQFLYGGCE GNANNFYTWE ACDDACWRIE KVPKVCRLQV SVDDQCEGST EKYFFNLSSM 120 TCEKFFΞGGC HRNRIENRFP DEATCMGFCA PKKIPSFCYS PKDEGLCSAN VTRYYFNPRY 180 RTCDAFTYTG CGGNDNNFVS REDCKRACAK ALKKKKKMPK LRFASRIRKI RKKQF
Seq ID NO: 25 DNA sequence Nucleic Acid Accession #: NM_005458.1 Coding sequence: 1..2825
11 21 31 41 SI
I I I I I
ATGGCTTCCC CGCGGAGGTC CGGGCAGCCA GGGCGGCCGC CGCCGCCGCC ACCGCCGCCC 60
GCGCGCCTGC TACTGCTACT GCTGCTGCCG CTGCTGCTGC CTCTGGCGCC CGGGGCCTGG 120
GGCTGGGCGC GGGGCGCCCC CCGGCCGCCG CCCAGCAGCC CGCCGCTCTC CATCATGGGC 180
CTCATGCCGC TCACCAAGGA GGTGGCCAAG GGCAGCATCG GGCGCGGTGT GCTCCCCGCC 240
GTGGAACTGG CCATCGAGCA GATCCGCAAC GAGTCACTCC TGCGCCCCTA CTTCCTCGAC 300
CTGCGGCTCT ATGACACGGA GTGCGACAAC GCAAAAGGGT TGAAAGCCTT CTACGATGCA 360
ATAAAATACG GGCCGAACCA CTTGATGGTG TTTGGAGGCG TCTGTCCATC CGTCACATCC 420
ATCATTGCAG AGTCCCTCCA AGGCTGGAAT CTGGTGCAGC TTTCTTTTGC TGCAACCACG 480
CCTGTTCTAG CCGATAAGAA AAAATACCCT TATTTCTTTC GGACCGTCCC ATCAGACAAT 540
GCGGTGAATC CAGCCATTCT GAAGTTGCTC AAGCACTACC AGTGGAAGCG CGTGGGCACG 600
CTGACGCAAG ACGTTCAGAG GTTCTCTGAG GTGCGGAATG ACCTGACTGG AGTTCTGTAT 660
GGCGAGGACA TTGAGATTTC AGACACCGAG AGCTTCTCCA ACGATCCCTβ TACCAGTGTC 720
AAAAAGCTGA AGGGGAATGA TGTGCGGATC ATCCTTGGCC AGTTTGACCA GAATATGGCA 780
GCAAAAGTGT TCTGTTGTGC ATACGAGGAG AACATGTATG GTAGTAAATA TCAGTGGATC 840
ATTCCGGGCT GGTACGAGCC TTCTTGGTGG GAGCAGGTGC ACACGGAAGC CAACTCATCC 900
CGCTGCCTCC GGAAGAATCT GCTTGCTGCC ATGGAGGGCT ACATTGGCGT GGATTTCGAG 960
CCCCTGAGCT CCAAGCAGAT CAAGACCATC TCAGGAAAGA CTCCACAGCA GTATGAGAGA 1020
GAGTACAACA ACAAGCGGTC AGGCGTGGGG CCCAGCAAGT TCCACGGGTA CGCCTACGAT 1080
GGCATCTGGG TCATCGCCAA GACACTGCAG AGGGCCATGG AGACACTGCA TGCCAGCAGC 1140
CGGCACCAGC GGATCCAGGA CTTCAACTAC ACGGACCACA CGCTGGGCAG GATCATCCTC 1200
AATGCCATGA ACGAGACCAA CTTCTTCGGG GTCACGGGTC AAGTTGTATT CCGGAATGGG 1260
GAGAGAATGG GGACCATTAA ATTTACTCAA TTTCAAGACA GCAGGGAGGT GAAGGTGGGA 1320
GAGTACAACG CTGTGGCCGA CACACTGGAG ATCATCAATG ACACCATCAG GTTCCAAGGA 1380
TCCGAACCAC CAAAAGACAA GACCATCATC CTGGAGCAGC TGCGGAAGAT CTCCCTACCT 1440
CTCTACAGCA TCCTCTCTGC CCTCACCATC CTCGGGATGA TCATGGCCAG TGCTTTTCTC 1500
TTCTTCAACA TCAAGAACCG GAATCAGAAG CTCATAAAGA TGTCGAGTCC ATACATGAAC 1560
AACCTTATCA TCCTTGGAGG GATGCTCTCC TATGCTTCCA TATTTCTCTT TGGCCTTGAT 1620
GGATCCTTTG TCTCTGAAAA GACCTTTGAA ACACTTTGCA CCGTCAGGAC CTGGATTCTC 1680
ACCGTGGGCT ACACGACCGC TTTTGGGGCC ATGTTTGCAA AGACCTGGAG AGTCCACGCC 1740
ATCTTCAAAA ATGTGAAAAT GAAGAAGAAG ATCATCAAGG ACCAGAAACT GCTTGTGATC 1800
GTGGGGGGCA TGCTGCTGAT CGACCTGTGT ATCCTGATCT GCTGGCAGGC TGTGGACCCC 1860
CTGCGAAGGA CAGTGGAGAA GTACAGCATG GAGCCGGACC CAGCAGGACG GGATATCTCC 1920
ATCCGCCCTC TCCTGGAGCA CTGTGAGAAC ACCCATATGA CCATCTGGCT TGGCATCGTC 1980
TATGCCTACA AGGGACTTCT CATGTTGTTC GGTTGTTTCT TAGCTTGGGA GACCCGCAAC 2040
GTCAGCATCC CCGCACTCAA CGACAGCAAG TACATCGGGA TGAGTGTCTA CAACGTGGGG 2100
ATCATGTGCA TCATCGGGGC CGCTGTCTCC TTCCTGACCC GGGACCAGCC CAATGTGCAG 2160
TTCTGCATCG TGGCTCTGGT CATCATCTTC TGCAGCACCA TCACCCTCTG CCTGGTATTC 2220
GTGCCGAAGC TCATCACCCT GAGAACAAAC CCAGATGCAG CAACGCAGAA CAGGCGATTC 2280
CAGTTCACTC AGAATCAGAA GAAAGAAGAT TCTAAAACGT CCACCTCGGT CACCAGTGTG 2340
AACCAAGCCA GCACATCCCG CCTGGAGGGC CTACAGTCAG AAAACCATCG CCTGCGAATG 2400 AAGATCACAG AGCTGGATAA AGACTTGGAA GAGGTCACCA TGCAGCTGCA GGACACACCA 2460
GAAAAGACCA CCTACATTAA ACAGAACCAC TACCAAGAGC TCAATGACAT CCTCAACCTG 2520
GGAAACTTCA CTGAGAGCAC AGATGGAGGA AAGGCCATTT TAAAAAATCA CCTCGATCAA 2580
AATCCCCAGC TACAGTGGAA CACAACAGAG CCCTCTCGAA CATGCAAAGA TCCTATAGAA 2640
GATATAAACT CTCCAGAACA CATCCAGCGT CGGCTGTCCC TCCAGCTCCC CATCCTCCAC 2700
CACGCCTACC TCCCATCCAT CGGAGGCGTG GACGCCAGCT GTGTCAGCCC CTGCGTCAGC 2760
CCCACCGCCA GCCCCCGCCA CAGACATGTG CCACCCTCCT TCCGAGTCAT GGTCTCGGGC 2820
CTGTAA
Seq ID NO: 26 Protein sequence
Protein Accession tt: NP_005449.1
1 11 21 31 41 51
1 1 1 I 1 1 | 1 1 MASPRRSGQP GRPPPPPPPP ARLLLLLLLP LLLPLAPGAW GWARGAPRPP PSSPPLSIMG 60
LMPLTKEVAK GSIGRGVLPA VELAIEQIRN ESLLRPYFLD LRLYDTECDN AKGLKAFYDA 120
IKYGPNHLMV FGGVCPSVTS IIAESLQGWN LVQLSFAATT PVLADKKKYP YFFRTVPSDN 180
AVNPAILKLL KHYQWKRVGT LTQDVQRFSE VRNDLTGVLY GEDIEISDTE SFSNDPCTSV 240
KKLKGNDVRI ILGQFDQNMA AKVFCCAYEE NMYGSKYQWI IPGWYEPSWW EQVHTEANSS 300
RCLRKNLLAA MEGYIGVDFE PLSSKQIKTI SGKTPQQYER EYNNKRSGVG PSKFHGYAYD 360
GIWVIAKTLQ RAMETLHASS RHQRIQDFNY TDHTLGRIIL NAMNETNFFG VTGQWFRNG 420
ERMGTIKFTQ FQDSREVKVG EYNAVADTLE IINDTIRFQG SEPPKDKTII LEQLRKISLP 480
LYSILSALTI LGMIMASAFL FFNIKNRNQK LIKMSSPYMN NLIILGGMLS YASIFLFGLD 540
GSFVSEKTFE TLCTVRT IL TVGYTTAFGA MFAKTWRVHA IFKNVKMKKK IIKDQKLLVI 600
VGGMLLIDLC ILICWQAVDP LRRTVEKYΞM EPDPAGRDIS IRPLLEHCEN THMTIWLGIV 660
YAYKGLLMLF GCFLAWETRN VSIPALNDSK YIGMSVYNVG IMCIIGAAVS FLTRDQPNVQ 720
FCIVALVIIF CSTITLCLVF VPKLITLRTN PDAATQNRRF QFTQNQKKED SKTSTSVTSV 780
NQASTSRLEG LQSENHRLRM KITELDKDLE EVTMQLQDTP EKTTYIKQNH YQELNDILNL 840
GNFTESTDGG KAILKNHLDQ NPQLQWNTTE PSRTCKDPIE DINSPEHIQR RLSLQLPILH 900
HAYLPSIGGV DASCVSPCVS PTASPRHRHV PPSFRVMVSG L
Seq ID NO: 27 DNA sequence
Nucleic Acid Accession ft: NM_000450.1 Coding sequence: 117..1949
1 11 21 31 41 51
I I 1 1 11 11 | 1
CCTGAGACAG AGGCAGCAGT GATACCCACC TGAGAGATCC TGTGTTTGAA CAACTGCTTC 60
CCAAAACGGA AAGTATTTCA AGCCTAAACC TTTGGGTGAA AAGAACTCTT GAAGTCATGA 120
TTGCTTCACA GTTTCTCTCA GCTCTCACTT TGGTGCTTCT CATTAAAGAG AGTGGAGCCT 180
GGTCTTACAA CACCTCCACG GAAGCTATGA CTTATGATGA GGCCAGTGCT TATTGTCAGC 240
AAAGGTACAC ACACCTGGTT GCAATTCAAA ACAAAGAAGA GATTGAGTAC CTAAACTCCA 300
TATTGAGCTA TTCACCAAGT TATTACTGGA TTGGAATCAG AAAAGTCAAC AATGTGTGGG 360
TCTGGGTAGG AACCCAGAAA CCTCTGACAG AAGAAGCCAA GAACTGGGCT CCAGGTGAAC 420
CCAACAATAG GCAAAAAGAT GAGGACTGCG TGGAGATCTA CATCAAGAGA GAAAAAGATG 480
TGGGCATGTG GAATGATGAG AGGTGCAGCA AGAAGAAGCT TGCCCTATGC TACACAGCTG 540
CCTGTACCAA TACATCCTGC AGTGGCCACG GTGAATGTGT AGAGACCATC AATAATTACA 600
CTTGCAAGTG TGACCCTGGC TTCAGTGGAC TCAAGTGTGA GCAAATTGTG AACTGTACAG 660
CCCTGGAATC CCCTGAGCAT GGAAGCCTGG TTTGCAGTCA CCCACTGGGA AACTTCAGCT 720
ACAATTCTTC CTGCTCTATC AGCTGTGATA GGGGTTACCT GCCAAGCAGC ATGGAGACCA 780
TGCAGTGTAT GTCCTCTGGA GAATGGAGTG CTCCTATTCC AGCCTGCAAT GTGGTTGAGT 840
GTGATGCTGT GACAAATCCA GCCAATGGGT TCGTGGAATG TTTCCAAAAC CCTGGAAGCT 900
TCCCATGGAA CACAACCTGT ACATTTGACT GTGAAGAAGG ATTTGAACTA ATGGGAGCCC 960
AGAGCCTTCA GTGTACCTCA TCTGGGAATT GGGACAACGA GAAGCCAACG TGTAAAGCTG 1020
TGACATGCAG GGCCGTCCGC CAGCCTCAGA ATGGCTCTGT GAGGTGCAGC CATTCCCCTG 1080
CTGGAGAGTT CACCTTCAAA TCATCCTGCA ACTTCACCTG TGAGGAAGGC TTCATGTTGC 1140
AGGGACCAGC CCAGGTTGAA TGCACCACTC AAGGGCAGTG GACACAGCAA ATCCCAGTTT 1200
GTGAAGCTTT CCAGTGCACA GCCTTGTCCA ACCCCGAGCG AGGCTACATG AATTGTCTTC 1260
CTAGTGCTTC TGGCAGTTTC CGTTATGGGT CCAGCTGTGA GTTCTCCTGT GAGCAGGGTT 1320
TTGTGTTGAA GGGATCCAAA AGGCTCCAAT GTGGCCCCAC AGGGGAGTGG GACAACGAGA 1380
AGCCCACATG TGAAGCTGTG AGATGCGATG CTGTCCACCA GCCCCCGAAG GGTTTGGTGA 1440
GGTGTGCTCA TTCCCCTATT GGAGAATTCA CCTACAAGTC CTCTTGTGCC TTCAGCTGTG 1500
AGGAGGGATT TGAATTATAT GGATCAACTC AACTTGAGTG CACATCTCAG GGACAATGGA 1560
CAGAAGAGGT TCCTTCCTGC CAAGTGGTAA AATGTTCAAG CCTGGCAGTT CCGGGAAAGA 1620
TCAACATGAG CTGCAGTGGG GAGCCCGTGT TTGGCACTGT GTGCAAGTTC GCCTGTCCTG 1680
AAGGATGGAC GCTCAATGGC TCTGCAGCTC GGACATGTGG AGCCACAGGA CACTGGTCTG 1740
GCCTGCTACC TACCTGTGAA GCTCCCACTG AGTCCAACAT TCCCTTGGTA GCTGGACTTT 1800
CTGCTGCTGG ACTCTCCCTC CTGACATTAG CACCATTTCT CCTCTGGCTT CGGAAATGCT 1860
TACGGAAAGC AAAGAAATTT GTTCCTGCCA GCAGCTGCCA AAGCCTTGAA TCAGACGGAA 1920
GCTACCAAAA GCCTTCTTAC ATCCTTTAAG TTCAAAAGAA TCAGAAACAG GTGCATCTGG 1980
GGAACTAGAG GGATACACTG AAGTTAACAG AGACAGATAA CTCTCCTCGG GTCTCTGGCC 2040
CTTCTTGCCT ACTATGCCAG ATGCCTTTAT GGCTGAAACC GCAACACCCA TCACCACTTC 2100
AATAGATCAA AGTCCAGCAG GCAAGGACGG CCTTCAACTG AAAAGACTCA GTGTTCCCTT 2160
TCCTACTCTC AGGATCAAGA AAGTGTTGGC TAATGAAGGG AAAGGATATT TTCTTCCAAG 2220
CAAAGGTGAA GAGACCAAGA . CTCTGAAATC TCAGAATTCC TTTTCTAACT CTCCCTTGCT 2280
CGCTGTAAAA TCTTGGCACA . GAAACACAAT ATTTTGTGGC TTTCTTTCTT TTGCCCTTCA 2340
CAGTGTTTCG ACAGCTGATT ACACAGTTGC TGTCATAAGA ATGAATAATA ATTATCCAGA 2400
GTTTAGAGGA AAAAAATGAC ! TAAAAATATT ATAACTTAAA AAAATGACAG ATGTTGAATG 2460
CCCACAGGCA AATGCATGGA . GGGTTGTTAA TGGTGCAAAT CCTACTGAAT GCTCTGTGCG 2520
AGGGTTACTA TGCACAATTT ' AATCACTTTC ATCCCTATGG GATTCAGTGC TTCTTAAAGA 2580
GTTCTTAAGG ATTGTGATAT TTTTACTTGC ATTGAATATA TTATAATCTT CCATACTTCT 2640
TCATTCAATA CAAGTGTGGT 1 AGGGACTTAA AAAACTTGTA AATGCTGTCA ACTATGATAT 2700
GGTAAAAGTT ACTTATTCTA . GATTACCCCC TCATTGTTTA TTAACAAATT ATGTTACATC 2760
TGTTTTAAAT TTATTTCAAA . AAGGGAAACT ATTGTCCCCT AGCAAGGCAT GATGTTAACC 2820 AGAATAAAGT TCTGAGTGTT TTTACTACAG TTGTTTTTTG AAAACATGGT AGAATTGGAG 2880 AGTAAAAACT GAATGGAAGG TTTGTATATT GTCAGATATT TTTTCAGAAA TATGTGGTTT 2940 CCACGATGAA AAACTTCCAT GAGGCCAAAC GTTTTGAACT AATAAAAGCA TAAATGCAAA 3000 CACACAAAGG TATAATTTTA TGAATGTCTT TGTTGGAAAA GAATACAGAA AGATGGATGT 3060 GCTTTGCATT CCTACAAAGA TGTTTGTCAG ATGTGATATG TAAACATAAT TCTTGTATAT 3120 TATGGAAGAT TTTAAATTCA CAATAGAAAC TCACCATGTA AAAGAGTCAT CTGGTAGATT 3180 TTTAACGAAT GAAGATGTCT AATAGTTATT CCCTATTTGT TTTCTTCTGT ATGTTAGGGT 3240 GCTCTGGAAG AGAGGAATGC CTGTGTGAGC AAGCATTTAT GTTTATTTAT AAGCAGATTT 3300 AACAATTCCA AAGGAATCTC CAGTTTTCAG TTGATCACTG GCAATGAAAA ATTCTCAGTC 3360 AGTAATTGCC AAAGCTGCTC TAGCCTTGAG GAGTGTGAGA ATCAAAACTC TCCTACACTT 3420 CCATTAACTT AGCATGTGTT GAAAAAAAAA GTTTCAGAGA AGTTCTGGCT GAACACTGGC 3480 AACGACAAAG CCAACAGTCA AAACAGAGAT GTGATAAGGA TCAGAACAGC AGAGGTTCTT 3540 TTAAAGGGGC AGAAAAACTC TGGGAAATAA GAGAGAACAA CTACTGTGAT CAGGCTATGT 3600 ATGGAATACA GTGTTATTTT CTTTGAAATT GTTTAAGTGT TGTAAATATT TATGTAAACT 3660 GCATTAGAAA TTAGCTGTGT GAAATACCAG TGTGGTTTGT GTTTGAGTTT TATTGAGAAT 3720 TTTAAATTAT AACTTAAAAT ATTTTATAAT TTTTAAAGTA TATATTTATT TAAGCTTATG 3780 TCAGACCTAT TTGACATAAC ACTATAAAGG TTGACAATAA ATGTGCTTAT GTTT
Seq ID NO: 28 Protein sequence Protein Accession #: NP 000441.1
11 21 31 41 51
I I I I I
MIASQFLSAL TLVLLIKESG AWSYNTSTEA MTYDEASAYC QQRYTHLVAI QNKEEIEYLN 60 SILSYSPSYY WIGIRKVNNV WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK 120 DVGMWNDERC SKKKLALCYT AACTNTSCSG HGECVETINN YTCKCDPGFS GLKCEQIVNC 180 TALESPEHGS LVCSHPLGNF SYNSSCSIΞC DRGYLPSSME TMQCMSSGEW SAPIPACNW 240 ECDAVTNPAN GFVECFQNPG SFPWNTTCTF DCEEGFELMG AQSLQCTSSG NWDNEKPTCK 300 AVTCRAVRQP QNGSVRCSHS PAGEFTFKSS CNFTCEEGFM LQGPAQVECT TQGQWTQQIP 360 VCEAFQCTAL SNPERGYMNC LPSASGSFRY GSSCEFSCEQ GFVLKGSKRL QCGPTGEWDN 420 EKPTCEAVRC DAVHQPPKGL VRCAHSPIGE FTYKSSCAFS CEEGFELYGS TQLECTSQGQ 480 WTEEVPSCQV VKCSSLAVPG KINMSCSGEP VFGTVCKFAC PEGWTLNGSA ARTCGATGHW 540 SGLLPTCEAP TESNIPLVAG LSAAGLSLLT LAPFLLWLRK CLRKAKKFVP ASSCQSLESD 600 GSYQKPSYIL
Seq ID NO: 29 DNA sequence
Nucleic Acid Accession ft: NM_007036
Coding sequence: 56..610
11 21 31 41 51
CTTCCCACCA GCAAAGACCA CGACTGGAGA GCCGAGCCGG AGGCAGCTGG GAAACATGAA 60 GAGCGTCTTG CTGCTGACCA CGCTCCTCGT GCCTGCACAC CTGGTGGCCG CCTGGAGCAA 120 TAATTATGCG GTGGACTGCC CTCAACACTG TGACAGCAGT GAGTGCAAAA GCAGCCCGCG 180 CTGCAAGAGG ACAGTGCTCG ACGACTGTGG CTGCTGCCGA GTGTGCGCTG CAGGGCGGGG 240 AGAAACTTGC TACCGCACAG TCTCAGGCAT GGATGGCATG AAGTGTGGCC CGGGGCTGAG 300 GTGTCAGCCT TCTAATGGGG AGGATCCTTT TGGTGAAGAG TTTGGTATCT GCAAAGACTG 360 TCCCTACGGC ACCTTCGGGA TGGATTGCAG AGAGACCTGC AACTGCCAGT CAGGCATCTG 420 TGACAGGGGG ACGGGAAAAT GCCTGAAATT CCCCTTCTTC CAATATTCAG TAACCAAGTC 480 TTCCAACAGA TTTGTTTCTC TCACGGAGCA TGACATGGCA TCTGGAGATG GCAATATTGT 540 GAGAGAAGAA GTTGTGAAAG AGAATGCTGC CGGGTCTCCC GTAATGAGGA AATGGTTAAA 600 TCCACGCTGA TCCCGGCTGT GATTTCTGAG AGAAGGCTCT ATTTTCGTGA TTGTTCAACA 660 CACAGCCAAC ATTTTAGGAA CTTTCTAGAT ATAGCATAAG TACATGTAAT TTTTGAAGAT 720 CCAAATTGTG ATGCATGGTG GATCCAGAAA ACAAAAAGTA GGATACTTAC AATCCATAAC 780 ATCCATATGA CTGAACACTT GTATGTGTTT GTTAAATATT CGAATGCATG TAGATTTGTT 840 AAATGTGTGT GTATAGTAAC ACTGAAGAAC TAAAAATGCA ATTTAGGTAA TCTTACATGG 900 AGACAGGTCA ACCAAAGAGG GAGCTAGGCA AAGCTGAAGA CCGCAGTGAG TCAAATTAGT 960 TCTTTGACTT TGATGTACAT TAATGTTGGG ATATGGAATG AAGACTTAAG AGCAGGAGAA 1020 GATGGGGAGG GGGTGGGAGT GGGAAATAAA ATATTTAGCC CTTCCTTGGT AGGTAGCTTC 1080 TCTAGAATTT AATTGTGCTT TTTGGCTTTG GGAAAAGTCA AAATAAAACA 1140 ACCAGAAAAC CCCTGAAGGA AGTAAGATGT TTGAAGCTTA TGGAAATTTG AGTAACAAAC 1200 AGCTTTGAAC TGAGAGCAAT TTCAAAAGGC TGCTGATGTA GTTCCCGGGT TACCTGTATC 1260 TGAAGGACGG TTCTGGGGCA TAGGAAACAC ATACACTTCC ATAAATAGCT TTAACGTATG 1320 CCACCTCAGA GATAAATCTA AGAAGTATTT TACCCACTGG TGGTTTGTGT GTGTATGAAG 1380 GTAAATATTT ATATATTTTT ATAAATAAAT GTGTTAGTGC AAGTCATCTT CCCTACCCAT 1440 ATTTATCATC CTCTTGAGGA AAGAAATCTA GTATTATTTG TTGAAAATGG TTAGAATAAA 1500 AACCTATGAC TCTATAAGGT TTTCAAACAT CTGAGGCATG ATAAATTTAT TATCCATAAT 1560 TATAGGAGTC ACTCTGGATT TCAAAAAATG TCAAAAAATG AGCAACAGAG GGACCTTATT 1620 TAAACATAAG TGCTGTGACT TCGGTGAATT TTCAATTTAA GGTATGAAAA TAAGTTTTTA 1680 GGAGGTTTGT AAAAGAAGAA TCAATTTTCA GCAGAAAACA TGTCAACTTT AAAATATAGG 1740 TGGAATTAGG AGTATATTTG AAAGAATCTT AGCACAAACA GGACTGTTGT ACTAGATGTT 1800 CTTAGGAAAT ATCTCAGAAG TATTTTATTT GAAGTGAAGA ACTTATTTAA GAATTATTTC 1860 AGTATTTACC TGTATTTTAT TCTTGAAGTT GGCCAACAGA GTTGTGAATG TGTGTGGAAG 1920 GCCTTTGAAT GTAAAGCTGC ATAAGCTGTT AGGTTTTGTT TTAAAAGGAC ATGTTTATTA 1980 TTGTTCAATA AAAAAGAACA AGATAC
Seq ID NO: 30 Protein sequence Protein Accession ft: NP_008967.1
1 11 21 31 41 51
I I I I I I
MKSVLLLTTL LVPAHLVAAW SNNYAVDCPQ HCDSSECKSS PRCKRTVLDD CGCCRVCAAG 60 RGETCYRTVS GMDGMKCGPG LRCQPSNGED PFGEEFGICK DCPYGTFGMD CRETCNCQSβ 120 ICDRGTGKCL KFPFFQYSVT KSSNRFVSLT EHDMASGDGN IVREEWKEN AAGSPVMRKW 180 LNPR
Seq ID NO: 31 DNA sequence
Nucleic Acid Accession #: NM_000963
Coding sequence: 135..1949
1 11 21 31 41 51
I I I I I I
CAATTGTCAT ACGACTTGCA GTGAGCGTCA GGAGCACGTC CAGGAACTCC TCAGCAGCGC 60
CTCCTTCAGC TCCACAGCCA GACGCCCTCA GACAGCAAAG CCTACCCCCG CGCCGCGCCC 120
TGCCCGCCGC TCGGATGCTC GCCCGCGCGC TGCTGCTGTG CGCGGTCCTG GCGCTCAGCC 180
ATACAGCAAA TCCTTGCTGT TCCCACCCAT GTCAAAACCG AGGTGTATGT ATGAGTGTGG 240
GATTTGACCA GTATAAGTGC GATTGTACCC GGACAGGATT CTATGGAGAA AACTGCTCAA 300
CACCGGAATT TTTGACAAGA ATAAAATTAT TTCTGAAACC CACTCCAAAC ACAGTGCACT 360
ACATACTTAC CCACTTCAAG GGATTTTGGA ACGTTGTGAA TAACATTCCC TTCCTTCGAA 420
ATGCAATTAT GAGTTATGTC TTGACATCCA GATCACATTT GATTGACAGT CCACCAACTT 480
ACAATGCTGA CTATGGCTAC AAAAGCTGGG AAGCCTTCTC TAACCTCTCC TATTATACTA 540
GAGCCCTTCC TCCTGTGCCT GATGATTGCC CGACTCCCTT GGGTGTCAAA GGTAAAAAGC 600
AGCTTCCTGA TTCAAATGAG ATTGTGGAAA AATTGCTTCT AAGAAGAAAG TTCATCCCTG 660
ATCCCCAGGG CTCAAACATG ATGTTTGCAT TCTTTGCCCA GCACTTCACG CATCAGTTTT 720
TCAAGACAGA TCATAAGCGA GGGCCAGCTT TCACCAACGG GCTGGGCCAT GGGGTGGACT 780
TAAATCATAT TTACGGTGAA ACTCTGGCTA GACAGCGTAA ACTGCGCCTT TTCAAGGATG 840
GAAAAATGAA ATATCAGATA ATTGATGGAG AGATGTATCC TCCCACAGTC AAAGATACTC 900
AGGCAGAGAT GATCTACCCT CCTCAAGTCC CTGAGCATCT ACGGTTTGCT GTGGGGCAGG 960
AGGTCTTTGG TCTGGTGCCT GGTCTGATGA TGTATGCCAC AATCTGGCTG CGGGAACACA 1020
ACAGAGTATG CGATGTGCTT AAACAGGAGC ATCCTGAATG GGGTGATGAG CAGTTGTTCC 1080
AGACAAGCAG GCTAATACTG ATAGGAGAGA CTATTAAGAT TGTGATTGAA GATTATGTGC 1140
AACACTTGAG TGGCTATCAC TTCAAACTGA AATTTGACCC AGAACTACTT TTCAACAAAC 1200
AATTCCAGTA CCAAAATCGT ATTGCTGCTG AATTTAACAC CCTCTATCAC TGGCATCCCC 1260
TTCTGCCTGA CACCTTTCAA ATTCATGACC AGAAATACAA CTATCAACAG TTTATCTACA 1320
ACAACTCTAT ATTGCTGGAA CATGGAATTA CCCAGTTTGT TGAATCATTC ACCAGGCAAA 1380
TTGCTGGCAG GGTTGCTGGT GGTAGGAATG TTCCACCCGC AGTACAGAAA GTATCACAGG 1440
CTTCCATTGA CCAGAGCAGG CAGATGAAAT ACCAGTCTTT TAATGAGTAC CGCAAACGCT 1500
TTATGCTGAA GCCCTATGAA TCATTTGAAG AACTTACAGG AGAAAAGGAA ATGTCTGCAG 1560
AGTTGGAAGC ACTCTATGGT GACATCGATG CTGTGGAGCT GTATCCTGCC CTTCTGGTAG 1620
AAAAGCCTCG GCCAGATGCC ATCTTTGGTG AAACCATGGT AGAAGTTGGA GCACCATTCT 1680
CCTTGAAAGG ACTTATGGGT AATGTTATAT GTTCTCCTGC CTACTGGAAG CCAAGCACTT 1740
TTGGTGGAGA AGTGGGTTTT CAAATCATCA ACACTGCCTC AATTCAGTCT CTCATCTGCA 1800
ATAACGTGAA GGGCTGTCCC TTTACTTCAT TCAGTGTTCC AGATCCAGAG CTCATTAAAA 1860
CAGTCACCAT CAATGCAAGT TCTTCCCGCT CCGGACTAGA TGATATCAAT CCCACAGTAC 1920
TACTAAAAGA ACGTTCGACT GAACTGTAGA AGTCTAATGA TCATATTTAT TTATTTATAT 1980
GAACCATGTC TATTAATTTA ATTATTTAAT AATATTTATA TTAAACTCCT TATGTTACTT 2040
AACATCTTCT GTAACAGAAG TCAGTACTCC TGTTGCGGAG AAAGGAGTCA TACTTGTGAA 2100
GACTTTTATG TCACTACTCT AAAGATTTTG CTGTTGCTGT TAAGTTTGGA AAACAGTTTT 2160
TATTCTGTTT TATAAACCAβ AGAGAAATGA GTTTTGACGT CTTTTTACTT GAATTTCAAC 2220
TTATATTATA AGAACGAAAG TAAAGATGTT TGAATACTTA AACACTATCA CAAGATGGCA 2280
AAATGCTGAA AGTTTTTACA CTGTCGATGT TTCCAATGCA TCTTCCATGA TGCATTAGAA 2340
GTAACTAATG TTTGAAATTT TAAAGTACTT TTGGTTATTT TTCTGTCATC AAACAAAAAC 2400
AGGTATCAGT GCATTATTAA ATGAATATTT AAATTAGACA TTACCAGTAA TTTCATGTCT 2460
ACTTTTTAAA ATCAGCAATG AAACAATAAT TTGAAATTTC TAAATTCATA GGGTAGAATC 2520
ACCTGTAAAA GCTTGTTTGA TTTCTTAAAG TTATTAAACT TGTACATATA CCAAAAAGAA 2580
GCTGTCTTGG ATTTAAATCT GTAAAATCAG ATGAAATTTT ACTACAATTG CTTGTTAAAA 2640
TATTTTATAA GTGATGTTCC TTTTTCACCA AGAGTATAAA CCTTTTTAGT GTGACTGTTA 2700
AAACTTCCTT TTAAATCAAA ATGCCAAATT TATTAAGGTG GTGGAGCCAC TGCAGTGTTA 2760
TCTCAAAATA AGAATATTTT GTTGAGATAT TCCAGAATTT GTTTATATGG CTGGTAACAT 2820
GTAAAATCTA TATCAGCAAA AGGGTCTACC TTTAAAATAA GCAATAACAA AGAAGAAAAC 2880
CAAATTATTG TTCAAATTTA GGTTTAAACT TTTGAAGCAA ACTTTTTTTT ATCCTTGTGC 2940
ACTGCAGGCC TGGTACTCAG ATTTTGCTAT GAGGTTAATG AAGTACCAAG CTGTGCTTGA 3000
ATAACGATAT GTTTTCTCAG ATTTTCTGTT GTACAGTTTA ATTTAGCAGT CCATATCACA 3060
TTGCAAAAGT AGCAATGACC TCATAAAATA CCTCTTCAAA ATGCTTAAAT TCATTTCACA 3120
CATTAATTTT ATCTCAGTCT TGAAGCCAAT TCAGTAGGTG CATTGGAATC AAGCCTGGCT 3180
ACCTGCATGC TGTTCCTTTT CTTTTCTTCT TTTAGCCATT TTGCTAAGAG ACACAGTCTT 3240
CTCATCACTT CGTTTCTCCT ATTTTGTTTT ACTAGTTTTA AGATCAGAGT TCACTTTCTT 3300
TGGACTCTGC CTATATTTTC TTACCTGAAC TTTTGCAAGT TTTCAGGTAA ACCTCAGCTC 3360
AGGACTGCTA TTTAGCTCCT CTTAAGAAGA TTAAAAGAGA AAAAAAAAGG CCCTTTTAAA 3420
AATAGTATAC ACTTATTTTA AGTGAAAAGC AGAGAATTTT ATTTATAGCT AATTTTAGCT 3480
ATCTGTAACC AAGATGGATG CAAAGAGGCT AGTGCCTCAG AGAGAACTGT ACGGGGTTTG 3540
TGACTGGAAA AAGTTACGTT CCCATTCTAA TTAATGCCCT TTCTTATTTA AAAACAAAAC 3600
CAAATGATAT CTAAGTAGTT CTCAGCAATA ATAATAATGA CGATAATACT TCTTTTCCAC 3660
ATCTCATTGT CACTGACATT TAATGGTACT GTATATTACT TAATTTATTG AAGATTATTA 3720
TTTATGTCTT ATTAGGACAC TATGGTTATA AACTGTGTTT AAGCCTACAA TCATTGATTT 3780
TTTTTTGTTA TGTCACAATC AGTATATTTT CTTTGGGGTT ACCTCTCTGA ATATTATGTA 3840
AACAATCCAA AGAAATGATT GTATTAAGAT TTGTGAATAA ATTTTTAGAA ATCTGATTGG 3900
CATATTGAGA TATTTAAGGT TGAATGTTTG TCCTTAGGAT AGGCCTATGT GCTAGCCCAC 3960
AAAGAATATT GTCTCATTAG CCTGAATGTG CCATAAGACT GACCTTTTAA AATGTTTTGA 4020
GGGATCTGTG GATGCTTCGT TAATTTGTTC AGCCACAATT TATTGAGAAA ATATTCTGTG 4080
TCAAGCACTG TGGGTTTTAA TATTTTTAAA TCAAACGCTG ATTACAGATA ATAGTATTTA 4140
TATAAATAAT TGAAAAAAAT TTTCTTTTGG GAAGAGGGAG AAAATGAAAT AAATATCATT 4200
AAAGATAACT CAGGAGAATC TTCTTTACAA TTTTACGTTT AGAATGTTTA AGGTTAAGAA 4260
AGAAATAGTC AATATGCTTG TATAAAACAC TGTTCACTGT TTTTTTTAAA AAAAAAACTT 4320
GATTTGTTAT TAACATTGAT CTGCTGACAA AACCTGGGAA TTTGGGTTGT GTATGCGAAT 4380
GTTTCAGTGC CTCAGACAAA TGTGTATTTA ACTTATGTAA AAGATAAGTC TGGAAATAAA 4440 TGTCTGTTTA TTTTTGTACT ATTTA Seq ID NO : 32 Protein sequence Protein Accession ft : NP_000954
1 11 21 31 41 51 I I 1 I I I
MLARALLLCA VLALSHTANP CCSHPCQNRG VCMSVGFDQY KCDCTRTGFY GENCSTPEFL 60
TRIKLFLKPT PNTVHYILTH FKGFWNWNN IPFLRNAIMS YVLTSRSHLI DSPPTYNADY 120
GYKSWEAFSN LSYYTRALPP VPDDCPTPLG VKGKKQLPDS NEIVEKLLLR RKFIPDPQGS 180
NMMFAFFAQH FTHQFFKTDH KRGPAFTNGL GHGVDLNHIY GETLARQRKL RLFKDGKMKY 240 QIIDGEMYPP TVKDTQAEMI YPPQVPEHLR FAVGQEVFGL VPGLMMYATI WLREHNRVCD 300
VLKQEHPEWG DEQLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE LLFNKQFQYQ 360
NRIAAEFNTL YHWHPLLPDT FQIHDQKYNY QQFIYNNSIL LEHGITQFVE SFTRQIAGRV 420
AGGRNVPPAV QKVSQASIDQ SRQMKYQSFN EYRKRFMLKP YESFEELTGE KEMSAELEAL 480
YGDIDAVELY PALLVEKPRP DAIFGETMVE VGAPFSLKGL MGNVICSPAY WKPSTFGGEV 540 GFQIINTASI QSLICNNVKG CPFTSFSVPD PELIKTVTIN ASSSRSGLDD INPTVLLKER 600 STEL
Seq ID NO : 33 DNA sequence Nucleic Acid Accession ft : NM_001508 . 1 Coding sequence : 1 . . 1361
1 11 21 31 41 51
I I I I I I
ATGGCTTCAC CCAGCCTCCC GGGCAGTGAC TGCTCCCAAA TCATTGATCA CAGTCATGTC 60 CCCGAGTTTG AGGTGGCCAC CTGGATCAAA ATCACCCTTA TTCTGGTGTA CCTGATCATC 120
TTCGTGATGG GCCTTCTGGG GAACAGCGTC ACCATTCGGG TCACCCAGGT GCTGCAGAAG 180
AAAGGATACT TGCAGAAGGA GGTGACAGAC CACATGGTGA GTTTGGCTTG CTCGGACATC 240
TTGGTGTTCC TCATCGGCAT GCCCATGGAG TTCTACAGCA TCATCTGGAA TCCCCTGACC 300
ACGTCCAGCT ACACCCTGTC CTGCAAGCTG CACACTTTCC TCTTCGAGGC CTGCAGCTAC 360 GCTACGCTGC TGCACGTGCT GACGCTCAGC TTTGAGCGCT ACATCGCCAT CTGTCACCCC 420
TTCAGGTACA AGGCTGTGTC GGGACCTTGC CAGGTGAAGC TGCTGATTGG CTTCGTCTGG 480
GTCACCTCCG CCCTGGTGGC ACTGCCCTTG CTGTTTGCCA TGGGTACTGA GTACCCCCTG 540
GTGAACGTGC CCAGCCACCG GGGTCTCACT TGCAACCGCT CCAGCACCCG CCACCACGAG 600
CAGCCCGAGA CCTCCAATAT GTCCATCTGT ACCAACCTCT CCAGCCGCTG GACCGTGTTC 660 CAGTCCAGCA TCTTCGGCGC CTTCGTGGTC TACCTCGTGG TCCTGCTCTC CGTAGCCTTC 720
ATGTGCTGGA ACATGATGCA GGTGCTCATG AAAAGCCAGA AGGGCTCGCT GGCCGGGGGC 780
ACGCGGCCTC CGCAGCTGAG GAAGTCCGAG AGCGAAGAGA GCAGGACCGC CAGGAGGCAG 840
ACCATCATCT TCCTGAGGCT GATTGTTGTG ACATTGGCCG TATGCTGGAT GCCCAACCAG 900
ATTCGGAGGA TCATGGCTGC GGCCAAACCC AAGCACGACT GGACGAGGTC CTACTTCCGG 960 GCGTACATGA TCCTCCTCCC CTTCTCGGAG ACGTTTTTCT ACCTCAGCTC GGTCATCAAC 1020
CCGCTCCTGT ACACGGTGTC CTCGCAGCAG TTTCGGCGGG TGTTCGTGCA GGTGCTGTGC 1080
TGCCGCCTGT CGCTGCAGCA CGCCAACCAC GAGAAGCGCC TGCGCGTACA TGCGCACTCC 1140
ACCACCGACA GCGCCCGCTT TGTGCAGCGC CCGTTGCTCT TCGCGTCCCG GCGCCAGTCC 1200
TCTGCAAGGA GAACTGAGAA GATTTTCTTA AGCACTTTTC AGAGCGAGGC CGAGCCCCAG 1260 TCTAAGTCCC AGTCATTGAG TCTCGAGTCA CTAGAGCCCA ACTCAGGCGC GAAACCAGCC 1320 AATTCTGCTG CAGAGAATGG TTTTCAGGAG CATGAAGTTT GA
Seq ID NO: 34 Protein sequence Protein Accession #: NP_001499.1
1 11 21 31 41 51
I I I I I I
MASPSLPGSD CSQIIDHSHV PEFEVATWIK ITLILVYLII FVMGLLGNSV TIRVTQVLQK 60
KGYLQKEVTD HMVSLACSDI LVFLIGMPME FYSIIWNPLT TSSYTLSCKL HTFLFEACSY 120
ATLLHVLTLS FERYIAICHP FRYKAVSGPC QVKLLIGFVW VTSALVALPL LFAMGTEYPL 180
VNVPSHRGLT CNRSSTRHHE QPETSNMSIC TNLSSRWTVF QSSIFGAFW YLWLLSVAF 240
MCWNMMQVLM KSQKGSLAGG TRPPQLRKSE SEESRTARRQ TIIFLRLIW TLAVCWMPNQ 300
IRRIMAAAKP KHDWTRSYFR AYMILLPFSE TFFYLSSVIN PLLYTVSSQQ FRRVFVQVLC 360
CRLSLQHANH EKRLRVHAHS TTDSARFVQR PLLFASRRQS SARRTEKIFL STFQSEAEPQ 420 SKSQSLSLES LEPNSGAKPA NSAAENGFQE HEV
Seq ID NO : 35 DNA sequence
Nucleic Acid Accession # : NM_006475 .1
Coding sequence : 28 . .2538
1 11 21 31 41 51
I I I I I I
AACAGAACTG CAACGGAGAG ACTCAAGATG ATTCCCTTTT TACCCATGTT TTCTCTACTA 60
TTGCTGCTTA TTGTTAACCC TATAAACGCC AACAATCATT ATGACAAGAT CTTGGCTCAT 120
AGTCGTATCA GGGGTCGGGA CCAAGGCCCA AATGTCTGTG CCCTTCAACA GATTTTGGGC 180
ACCAAAAAGA AATACTTCAG CACTTGTAAG AACTGGTATA AAAAGTCCAT CTGTGGACAG 240
AAAACGACTG TTTTATATGA ATGTTGCCCT GGTTATATGA GAATGGAAGG AATGAAAGGC 300
TGCCCAGCAG TTTTGCCCAT TGACCATGTT TATGGCACTC TGGGCATCGT GGGAGCCACC 360
ACAACGCAGC GCTATTCTGA CGCCTCAAAA CTGAGGGAGG AGATCGAGGG AAAGGGATCC 420
TTCACTTACT TTGCACCGAG TAATGAGGCT TGGGACAACT TGGATTCTGA TATCCGTAGA 480
GGTTTGGAGA GCAACGTGAA TGTTGAATTA CTGAATGCTT TACATAGTCA CATGATTAAT 540
AAGAGAATGT TGACCAAGGA CTTAAAAAAT GGCATGATTA TTCCTTCAAT GTATAACAAT 600
TTGGGGCTTT TCATTAACCA TTATCCTAAT GGGGTTGTCA CTGTTAATTG TGCTCGAATC 660
ATCCATGGGA ACCAGATTGC AACAAATGGT GTTGTCCATG TCATTGACCG TGTGCTTACA 720
CAAATTGGTA CCTCAATTCA AGACTTCATT GAAGCAGAAG ATGACCTTTC ATCTTTTAGA 780
GCAGCTGCCA TCACATCGGA CATATTGGAG GCCCTTGGAA GAGACGGTCA CTTCACACTC 840
TTTGCTCCCA CCAATGAGGC TTTTGAGAAA CTTCCACGAG GTGTCCTAGA AAGGTTCATG 900
GGAGACAAAG TGGCTTCCGA AGCTCTTATG AAGTACCACA TCTTAAATAC TCTCCAGTGT 960
TCTGAGTCTA TTATGGGAGG AGCAGTCTTT GAGACGCTGG AAGGAAATAC AATTGAGATA 1020 GGATGTGACG GTGACAGTAT AACAGTAAAT GGAATCAAAA TGGTGAACAA AAAGGATATT 1080 GTGACAAATA ATGGTGTGAT CCATTTGATT GATCAGGTCC TAATTCCTGA TTCTGCCAAA 1140 CAAGTTATTG AGCTGGCTGG AAAACAGCAA ACGACCTTCA CGGATCTTGT GGCCCAATTA 1200 GGCTTGGCAT CTGCTCTGAG GCCAGATGGA GAATACACTT TGCTGGCACC TGTGAATAAT 1260 GCATTTTCTG ATGATACTCT CAGCATGGTT CAGCGCCTCC TTAAATTAAT TCTGCAGAAT 1320 CACATATTGA AAGTAAAAGT TGGCCTTAAT GAGCTTTACA ACGGGCAAAT ACTGGAAACC 1380 ATCGGAGGCA AACAGCTCAG AGTCTTCGTA TATCGTACAG CTGTCTGCAT TGAAAATTCA 1440 TGCATGGAGA AAGGGAGTAA GCAAGGGAGA AACGGTGCGA TTCACATATT CCGCGAGATC 1500 ATCAAGCCAG CAGAGAAATC CCTCCATGAA AAGTTAAAAC AAGATAAGCG CTTTAGCACC 1560 TTCCTCAGCC TACTTGAAGC TGCAGACTTG AAAGAGCTCC TGACACAACC TGGAGACTGG 1620 ACATTATTTG TGCCAACCAA TGATGGTTTT AAGGGAATGA CTAGTGAAGA AAAAGAAATT 1680 CTGATACGGG ACAAAAATGC TCTTCAAAAC ATCATTCTTT ATCACCTGAC ACCAGGAGTT 1740 TTCATTGGAA AAGGATTTGA ACCTGGTGTT ACTAACATTT TAAAGACCAC ACAAGGAAGC 1800 AAAATCTTTC TGAAAGAAGT AAATGATACA CTTCTGGTGA ATGAATTGAA ATCAAAAGAA 1860 TCTGACATCA TGACAACAAA TGGTGTAATT CATGTTGTAG ATAAACTCCT CTATCCAGCA 1920 GACACACCTG TTGGAAATGA TCAACTGCTG GAAATACTTA ATAAATTAAT CAAATACATC 1980 CAAATTAAGT TTGTTCGTGG TAGCACCTTC AAAGAAATCC CCGTGACTGT CTATACAACT 2040 AAAATTATAA CCAAAGTTGT GGAACCAAAA ATTAAAGTGA TTGAAGGCAG TCTTCAGCCT 2100 ATTATCAAAA CTGAAGGACC CACACTAACA AAAGTCAAAA TTGAAGGTGA ACCTGAATTC 2160 AGACTGATTA AAGAAGGTGA AACAATAACT GAAGTGATCC ATGGAGAGCC AATTATTAAA 2220 AAATACACCA AAATCATTGA TGGAGTGCCT GTGGAAATAA CTGAAAAAGA GACACGAGAA 2280 GAACGAATCA TTACAGGTCC TGAAATAAAA TACACTAGGA TTTCTACTGG AGGTGGAGAA 2340 ACAGAAGAAA CTCTGAAGAA ATTGTTACAA GAAGAGGTCA CCAAGGTCAC CAAATTCATT 2400 GAAGGTGGTG ATGGTCATTT ATTTGAAGAT GAAGAAATTA AAAGACTGCT TCAGGGAGAC 2460 ACACCCGTGA GGAAGTTGCA AGCCAACAAA AAAGTTCAAG GTTCTAGAAG ACGATTAAGG 2520 GAAGGTCGTT CTCAGTGAAA ATCCAAAAAC CAGAAAAAAA TGTTTATACA ACCCTAAGTC 2580 AATAACCTGA CCTTAGAAAA TTGTGAGAGC CAAGTTGACT TCAGGAACTG AAACATGAGC 2640 ACAAAGAAGC AATCATCAAA TAATTCTGAA CACAAATTTA ATATTTTTTT TTCTGAATGA 2700 GAAACATGAG GGAAATTGTG GAGTTAGCCT CCTGTGGTAA AGGAATTGAA GAAAATATAA 2760 CACCTTACAC CCTTTTTCAT CTTGACATTA AAAGTTCTGG CTAACTTTGG AATCCATTAG 2820 AGAAAAATCC TTGTCACCAG ATTCATTACA ATTCAAATCG AAGAGTTGTG AACTGTTATC 2880 CCATTGAAAA GACCGAGCCT TGTATGTATG TTATGGATAC ATAAAATGCA CGCAAGCCAT 2940 TATCTCTCCA TGGGAAGCTA AGTTATAAAA ATAGGTGCTT GGTGTACAAA ACTTTTTATA 3000 TCAAAAGGCT TTGCACATTT CTATATGAGT GGGTTTACTG GTAAATTATG TTATTTTTTA 3060 CAACTAATTT TGTACTCTCA GAATGTTTGT CATATGCTTC TTGCAATGCA TATTTTTTAA 3120 TCTCAAACGT TTCAATAAAA CCATTTTTCA GATATAAAGA GAATTACTTC AAATTGAGTA 3180 ATTCAGAAAA ACTCAAGATT TAAGTTAAAA AGTGGTTTGG ACTTGGGAA
Seq ID NO: 36 Protein sequence Protein Accession #: NP 006466.1
FSTC 60
Figure imgf000963_0001
SDAS 120
KLREEIEGKG SFTYFAPSNE AWDNLDSDIR RGLESNVNVE LLNALHSHMI NKRMLTKDLK 180
NGMIIPSMYN NLGLFINHYP NGWTVNCAR IIHGNQIATN GWHVIDRVL TQIGTSIQDF 240
IEAEDDLSSF RAAAITSDIL EALGRDGHFT LFAPTNEAFE KLPRGVLERF MGDKVASEAL 300
MKYHILNTLQ CSESIMGGAV FETLEGNTIE IGCDGDSITV NGIKMVNKKD IVTNNGVIHL 360
IDQVLIPDSA KQVIELAGKQ QTTFTDLVAQ LGLASALRPD GEYTLLAPVN NAFSDDTLSM 420
VQRLLKLILQ NHILKVKVGL NELYNGQILE TIGGKQLRVF VYRTAVCIEN SCMEKGSKQG 480
RNGAIHIFRE IIKPAEKSLH EKLKQDKRFS TFLSLLEAAD LKELLTQPGD WTLFVPTNDA 540
FKGMTSEEKE ILIRDKNALQ NIILYHLTPG VFIGKGFEPG VTNILKTTQG SKIFLKEVND 600
TLLVNELKSK ESDIMTTNGV IHWDKLLYP ADTPVGNDQL LEILNKLIKY IQIKFVRGST 660
FKEIPVTVYT TKIITKWEP KIKVIEGSLQ PIIKTEGPTL TKVKIEGEPE FRLIKEGETI 720
TEVIHGEPII KKYTKIIDGV PVEITEKETR EERIITGPEI KYTRISTGGG ETEETLKKLL 780
QEEVTKVTKF IEGGDGHLFE DEEIKRLLQG DTPVRKLQAN KKVQGSRRRL REGRSQ
Seq ID NO: 37 DNA sequence
Nucleic Acid Accession ft: NM_002416 Coding sequence: 40..417
21 31 51
ATCCAATACA GGAGTGACTT GGAACTCCAT TCTATCACTA TGAAGAAAAG TGGTGTTCTT 60
TTCCTCTTGG GCATCATCTT GCTGGTTCTG ATTGGAGTGC AAGGAAGCCC AGTAGTGAGA 120
AAGGGTCGCT GTTCCTGCAT CAGCACCAAC CAAGGGACTA TCCACCTACA ATCCTTGAAA 180
GACCTTAAAC AATTTGCCCC AAGCCCTTCC TGCGAGAAAA TTGAAATCAT TGCTACACTG 240
AAGAATGGAG TTCAAACATG TCTAAACCCA GATTCRGCAG ATGTGAAGGA ACTGATTAAA 300
AAGTGGGAGA AACAGGTCAG CCAAAAGAAA AAGCAAAAGA ATGGGAAAAA ACATCAAAAA 360
AAGAAAGTTC TGAAAGTTCG AAAATCTCAA CGTTCTCGTC AAAAGAAGAC TACATAAGAG 420
ACCACTTGAC CAATAAGTAT TCTGTGTTAA AAATGTTCTA TTTTAATTAT ACCGCTATCA 480
TTCCAAAGGA GGATGGCATA TAATACAAAG GCTTATTAAT TTGACTAGAA AATTTAAAAC 540
ATTACTCTGA AATTGTAACT AAAGTTAGAA AGTTGATTTT AAGAATCCAA ACGTTAAGAA 600
TTGTTAAAGG CTATGATTGT CTTTGTTCTT CTACCACCCA CCAGTTGAAT TTCATCATGC 660
TTAAGGCCAT GATTTTAGCA ATACCCATGT CTACACAGAT GTTCACCCAA CCACATCCCA 720
CTCACAACAG CTGCCTGGAA GAGCAGCCCT AGGCTTCCAC GTACTGCAGC CTCCAGAGAG 780
TATCTGAGGC ACATGTCAGC AAGTCCTAAG CCTGTTAGCA TGCTGGTGAG CCAAGCAGTT 840
TGAAATTGAG CTGGACCTCA CCAAGCTGCT GTGGCCATCA ACCTCTGTAT TTGAATCAGC 900
CTACAGGCCT CACACACAAT GTGTCTGAGA GATTCATGCT GATTGTTATT GGGTATCACC 960
ACTGGAGATC ACCAGTGTGT GGCTTTCAGA GCCTCCTTTC TGGCTTTGGA AGCCATGTGA 1020
TTCCATCTTG CCCGCTCAGG CTGACCACTT TATTTCTTTT TGTTCCCCTT TGCTTCATTC 1080
AAGTCAGCTC TTCTCCATCC TACCACAATG CAGTGCCTTT CTTCTCTCCA GTGCACCTGT 1140
CATATGCTCT GATTTATCTG AGTCAACTCC TTTCTCATCT TGTCCCCAAC ACCCCACAGA 1200 AGTGCTTTCT TCTCCCAATT CATCCTCACT CAGTCCAGCT TAGTTCAAGT CCTGCCTCTT 1260 AAATAAACCT TTTTGGACAC ACAAATTATC TTAAAACTCC TGTTTCACTT GGTTCAGTAC 1320 CACATGGGTG AACACTCAAT GGTTAACTAA TTCTTGGGTG TTTATCCTAT CTCTCCAACC 1380 AGATTGTCAG CTCCTTGAGG GCAAGAGCCA CAGTATATTT CCCTGTTTCT TCCACAGTGC 1440 CTAATAATAC TGTGGAACTA GGTTTTAATA ATTTTTTAAT TGATGTTGTT ATGGGCAGGA 1500 TGGCAACCAG ACCATTGTCT CAGAGCAGGT GCTGGCTCTT TCCTGGCTAC TCCATGTTGG 1560 CTAGCCTCTG GTAACCTCTT ACTTATTATC TTCAGGACAC TCACTACAGG GACCAGGGAT 1620 GATGCAACAT CCTTGTCTTT TTATGACAGG ATGTTTGCTC AGCTTCTCCA ACAATAAGAA 1680 GCACGTGGTA AAACACTTGC GGATATTCTG GACTGTTTTT AAAAAATATA CAGTTTACCG 1740
10 AAAATCATAT AATCTTACAA TGAAAAGGAC TTTATAGATC AGCCAGTGAC CAACCTTTTC 1800 CCAACCATAC AAAAATTCCT TTTCCCGAAG GAAAAGGGCT TTCTCAATAA GCCTCAGCTT 1860 TCTAAGATCT AACAAGATAG CCACCGAGAT CCTTATCGAA ACTCATTTTA GGCAAATATG 1920 AGTTTTATTG TCCGTTTACT TGTTTCAGAG TTTGTATTGT GATTATCAAT TACCACACCA 1980 TCTCCCATGA AGAAAGGGAA CGGTGAAGTA CTAAGCGCTA GAGGAAGCAG CCAAGTCGGT 2040
15 TAGTGGAAGC ATGATTGGTG CCCAGTTAGC CTCTGCAGGA TGTGGAAACC TCCTTCCAGG 2100 GGAGGTTCAG TGAATTGTGT AGGAGAGGTT GTCTGTGGCC AGAATTTAAA CCTATACTCA 2160 CTTTCCCAAA TTGAATCACT GCTCACACTG CTGATGATTT AGAGTGCTGT CCGGTGGAGA 2220 TCCCACCCGA ACGTCTTATC TAATCATGAA ACTCCCTAGT TCCTTCATGT AACTTCCCTG 2280 AAAAATCTAA GTGTTTCATA AATTTGAGAG TCTGTGACCC ACTTACCTTG CATCTCACAG 2340 0 GTAGACAGTA TATAACTAAC AACCAAAGAC TACATATTGT CACTGACACA CACGTTATAA 2400 TCATTTATCA TATATATACA TACATGCATA CACTCTCAAA GCAAATAATT TTTCACTTCA 2460 AAACAGTATT GACTTGTATA CCTTGTAATT TGAAATATTT TCTTTGTTAA AATAGAATGG 2520 TATCAATAAA TAGACCATTA ATCAG
25 Seq ID NO: 38 Protein sequence Protein Accession #: NP 002407
1 11 21 31 41 51
~Λ I 1 I I I 1
OV MKKSGVLFLL GIILLVLIGV QGTPWRKGR CSCISTNQGT IHLQSLKDLK QFAPSPSCEK 60
IEIIATLKNG VQTCLNPDSA DVKELIKKWE KQVSQKKKQK NGKKHQKKKV LKVRKSQRSR 120
QKKTT
I
Seq ID NO: 39 DNA sequence 35 Nucleic Acid Accession #: NM_006670
Coding sequence: 85..1347
11 21 31 41 51
I I I I I
40 CCGGCTCGCG CCCTCCGGGC CCAGCCTCCC GAGCCTTCGG AGCGGGCGCC GTCCCAGCCC 60
AGCTCCGGGG AAACGCGAGC CGCGATGCCT GGGGGGTGCT CCCGGGGCCC CGCCGCCGGG 120
GACGGGCGTC TGCGGCTGGC GCGACTAGCG CTGGTACTCC TGGGCTGGGT CTCCTCGTCT 180
TCTCCCACCT CCTCGGCATC CTCCTTCTCC TCCTCGGCGC CGTTCCTGGC TTCCGCCGTG 240
TCCGCCCAGC CCCCGCTGCC GGACCAGTGC CCCGCGCTGT GCGAGTGCTC CGAGGCAGCG 300
45 CGCACAGTCA AGTGCGTTAA CCGCAATCTG ACCGAGGTGC CCACGGACCT GCCCGCCTAC 360
GTGCGCAACC TCTTCCTTAC CGGCAACCAG CTGGCCGTGC TCCCTGCCGG CGCCTTCGCC 420
CGCCGGCCGC CGCTGGCGGA GCTGGCCGCG CTCAACCTCA GCGGCAGCCG CCTGGACGAG 480
GTGCGCGCGG GCGCCTTCGA GCATCTGCCC AGCCTGCGCC AGCTCGACCT CAGCCACAAC 540
CCACTGGCCG ACCTCAGTCC CTTCGCTTTC TCGGGCAGCA ATGCCAGCGT CTCGGCCCCC 600
50 AGTCCCCTTG TGGAACTGAT CCTGAACCAC ATCGTGCCCC CTGAAGATGA GCGGCAGAAC 660
CGGAGCTTCG AGGGCATGGT GGTGGCGGCC CTGCTGGCGG GCCGTGCACT GCAGGGGCTC 720
CGCCGCTTGG AGCTGGCCAG CAACCACTTC CTTTACCTGC CGCGGGATGT GCTGGCCCAA 780
CTGCCCAGCC TCAGGCACCT GGACTTAAGT AATAATTCGC TGGTGAGCCT GACCTACGTG 840
TCCTTCCGCA ACCTGACACA TCTAGAAAGC CTCCACCTGG AGGACAATGC CCTCAAGGTC 900
55 CTTCACAATG GCACCCTGGC TGAGTTGCAA GGTCTACCCC ACATTAGGGT TTTCCTGGAC 960
AACAATCCCT GGGTCTGCGA CTGCCACATG GCAGACATGG TGACCTGGCT CAAGGAAACA 1020
GAGGTAGTGC AGGGCAAAGA CCGGCTCACC TGTGCATATC CGGAAAAAAT GAGGAATCGG 1080
GTCCTCTTGG AACTCAACAG TGCTGACCTG GACTGTGACC CGATTCTTCC CCCATCCCTG 1140
CAAACCTCTT ATGTCTTCCT GGGTATTGTT TTAGCCCTGA TAGGCGCTAT TTTCCTCCTG 1200
60 GTTTTGTATT TGAACCGCAA GGGGATAAAA AAGTGGATGC ATAACATCAG AGATGCCTGC 1260
AGGGATCACA TGGAAGGGTA TCATTACAGA TATGAAATCA ATGCGGACCC CAGATTAACA 1320
AACCTCAGTT CTAACTCGGA TGTCTGAGAA ATATTAGAGG ACAGACCAAG GACAACTCTG 1380
CATGAGATGT AGACTTAAGC TTTATCCCTA CTAGGCTTGC TCCACTTTCA TCCTCCACTA 1440
TAGATACAAC GGACTTTGAC TAAAAGCAGT GAAGGGGATT TGCTTCCTTG TTATGTAAAG 1500
65 TTTCTCGGTG TGTTCTGTTA ATGTAAGACG ATGAACAGTT GTGTATAGTG TTTTACCCTC 1560
TTCTTTTTCT TGGAACTCCT CAACACGTAT GGAGGGATTT TTCAGGTTTC AGCATGAACA 1620
TGGGCTTCTT GCTGTCTGTC TCTCTCTCAG TACAGTTCAA GGTGTAGCAA GTGTACCCAC 1680
ACAGATAGCA TTCAACAAAA GCTGCCTCAA CTTTTTCGAG AAAAATACTT TATTCATAAA 1740
TATCAGTTTT ATTCTCATGT ACCTAAGTTG TGGAGAAAAT AATTGCATCC TATAAACTGC 1800
70 CTGCAGACGT TAGCAGGCTC TTCAAAATAA CTCCATGGTG CACAGGAGCA CCTGCATCCA 1860
AGAGCATGCT TACATTTTAC TGTTCTGCAT ATTACAAAAA ATAACTTGCA ACTTCATAAC 1920
TTCTTTGACA AAGTAAATTA CTTTTTTGAT TGCAGTTTAT ATGAAAATGT ACTGATTTTT 1980
TTTTAATAAA CTGCATCGAG ATCCAACCGA CTGAATTGTT AAAAAAAAAA AAAAATAAAG 2040
ATTCTTAAAA GAA
75
Seq ID NO: 40 Protein sequence Protein Accession #: NP 006661
_,- 1 11 21 31 41 51
80 i i i i i i
MPGGCSRGPA AGDGRLRLAR LALVLLGWVS SSSPTSSASS FSSSAPFLAS AVSAQPPLPD 60 QCPALCECSE AARTVKCVNR NLTEVPTDLP AYVRNLFLTG NQLAVLPAGA FARRPPLAEL 120 AALNLSGSRL DEVRAGAFEH LPSLRQLDLS HNPLADLSPF AFSGSNASVS APSPLVELIL 180 NHIVPPEDER QNRSFEGMW AALLAGRALQ GLRRLELASN HFLYLPRDVL AQLPSLRHLD 240 LSNNSLVSLT YVSFRNLTHL ESLHLEDNAL KVLHNGTLAE LQGLPHIRVF LDNNPWVCDC 300
HMADMVTWLK ETEWQGKDR LTCAYPEKMR NRVLLELNSA DLDCDPILPP SLQTSYVFLG 360 IVLALIGAIF LLVLYLNRKG IKKWMHNIRD ACRDHMEGYH YRYEINADPR LTNLSSNSDV
5 Seq ID NO : 41 DNA sequence
Nucleic Acid Accession ft : Eos sequence Coding sequence : 1 . . 927
, _ 1 11 21 31 41 51
10 i i i i i i
ATGCCTGGGG GGTGCTCCCG GGGCCCCGCC GCCGGGGACG GGCGTCTGCG GCTGGCGCGA 60
CTAGCGCTGG TACTCCTGGG CTGGGTCTCC TCGTCTTCTC CCACCTCCTC GGCATCCTCC 120
TTCTCCTCCT CGGCGCCGTT CCTGGCTTCC GCCGTGTCCG CCCAGCCCCC GCTGCCGGAC 180
CAGTGCCCCG CGCTGTGCGA GTGCTCCGAG GCAGCGCGCA CAGTCAAGTG CGTTAACCGC 240
15 AATCTGACCG AGGTGCCCAC GGACCTGCCC GCCTACGTGC GCAACCTCTT CCTTACCGGC 300
AACCAGCTGG CCAGCAACCA CTTCCTTTAC CTGCCGCGGG ATGTGCTGGC CCAACTGCCC 360
AGCCTCAGGC ACCTGGACTT AAGTAATAAT TCGCTGGTGA GCCTGACCTA CGTGTCCTTC 420
CGCAACCTGA CACATCTAGA AAGCCTCCAC CTGGAGGACA ATGCCCTCAA GGTCCTTCAC 480
AATGGCACCC TGGCTGAGTT GCAAGGTCTA CCCCACATTA GGGTTTTCCT GGACAACAAT 540
20 CCCTGGGTCT GCGACTGCCA CATGGCAGAC ATGGTGACCT GGCTCAAGGA AACAGAGGTA 600
GTGCAGGGCA AAGACCGGCT CACCTGTGCA TATCCGGAAA AAATGAGGAA TCGGGTCCTC 660
TTGGAACTCA ACAGTGCTGA CCTGGACTGT GACCCGATTC TTCCCCCATC CCTGCAAACC 720
TCTTATGTCT TCCTGGGTAT TGTTTTAGCC CTGATAGGCG CTATTTTCCT CCTGGTTTTG 780
TATTTGAACC GCAAGGGGAT AAAAAAGTGG ATGCATAACA TCAGAGATGC CTGCAGGGAT 840
25 CACATGGAAG GGTATCATTA CAGATATGAA ATCAATGCGG ACCCCAGATT AACAAACCTC 900 AGTTCTAACT CGGATGTCCT CGAGTGA
Seq ID NO : 42 Protein sequence Protein Accession ft : Eos sequence
30
1 11 21 31 41 51
I I I I I I
MPGGCSRGPA AGDGRLRLAR LALVLLGWVS SSSPTSSASS FSSSAPFLAS AVSAQPPLPD 60
QCPALCECSE AARTVKCVNR NLTEVPTDLP AYVRNLFLTG NQLASNHFLY LPRDVLAQLP 120
35 SLRHLDLSNN SLVSLTYVSF RNLTHLESLH LEDNALKVLH NGTLAELQGL PHIRVFLDNN 180
PWVCDCHMAD MVTWLKETEV VQGKDRLTCA YPEKMRNRVL LELNSADLDC DPILPPSLQT 240
SYVFLGIVLA LIGAIFLLVL YLNRKGIKKW MHNIRDACRD HMEGYHYRYE INADPRLTNL 300 SSNSDVLE
40 Seq ID NO: 43 DNA sequence
Nucleic Acid Accession #: NM_058173
Coding sequence: 68..340
11 41
45 TTGC C I I
AGCGCC TTCTCTTAG GCTTTGAAGC ATTTTTGTCT GTGCTCCCTG ATCTTCAGGT 60
CACCACCATG AAGTTCTTAG CAGTCCTGGT ACTCTTGGGA GTTTCCATCT TTCTGGTCTC 120
TGCCCAGAAT CCGACAACAG CTGCTCCAGC TGACACGTAT CCAGCTACTG GTCCTGCTGA 180
TGATGAAGCC CCTGATGCTG AAACCACTGC TGCTGCAACC ACTGCGACCA CTGCTGCTCC 240
50 TACCACTGCA ACCACCGCTG CTTCTACCAC TGCTCGTAAA GACATTCCAG TTTTACCCAA 300
ATGGGTTGGG GATCTCCCGA ATGGTAGAGT GTGTCCCTGA GATGGAATCA GCTTGAGTCT 360
TCTGCAATTG GGTCACAACT ATTCATGCTT CCTGTGATTT CATCCAACTA CTTACCTTGC 420
CTACGATATC CCCTTTATCT CTAATCAGTT TATTTTCTTT CAAATAAAAA ATAACTATGA 480 GCGAGCTAAC AT
55
Seq ID NO: 44 Protein sequence Protein Accession tf: NP 477521
-,. 1 11 21 31 41 51
60 i i i i i i
MKFLAVLVLL GVSIFLVSAQ NPTTAAPADT YPATGPADDE APDAETTAAA TTATTAAPTT 60 ATTAASTTAR KDIPVLPKWV GDLPNGRVCP
Seq ID NO: 45 DNA sequence 65 Nucleic Acid Accession ft: NM_000095.1 Coding sequence: 26..2299
1 11 21 31 41 51
I I I I I I
70 CAGCACCCAG CTCCCCGCCA CCGCCATGGT CCCCGACACC GCCTGCGTTC TTCTGCTCAC 60
CCTGGCTGCC CTCGGCGCGT CCGGACAGGG CCAGAGCCCG TTGGGCTCAG ACCTGGGCCC 120
GCAGATGCTT CGGGAACTGC AGGAAACCAA CGCGGCGCTG CAGGACGTGC GGGACTGGCT 180
GCGGCAGCAG GTCAGGGAGA TCACGTTCCT GAAAAACACG GTGATGGAGT GTGACGCGTG 240
CGGGATGCAG CAGTCAGTAC GCACCGGCCT ACCCAGCGTG CGGCCCCTGC TCCACTGCGC 300
75 GCCCGGCTTC TGCTTCCCCG GCGTGGCCTG CATCCAGACG GAGAGCGGCG GCCGCTGCGG 360
CCCCTGCCCC GCGGGCTTCA CGGGCAACGG CTCGCACTGC ACCGACGTCA ACGAGTGCAA 420
CGCCCACCCC TGCTTCCCCC GAGTCCGCTG TATCAACACC AGCCCGGGGT TCCGCTGCGA 480
GGCTTGCCCG CCGGGGTACA GCGGCCCCAC CCACCAGGGC GTGGGGCTGG CTTTCGCCAA 540
GGCCAACAAG CAGGTTTGCA CGGACATCAA CGAGTGTGAG ACCGGGCAAC ATAACTGCGT 600
80 CCCCAACTCC GTGTGCATCA ACACCCGGGG CTCCTTCCAG TGCGGCCCGT GCCAGCCCGG 660
CTTCGTGGGC GACCAGGCGT CCGGCTGCCA GCGCGGCGCA CAGCGCTTCT GCCCCGACGG 720
CTCGCCCAGC GAGTGCCACG AGCATGCAGA CTGCGTCCTA GAGCGCGATG GCTCGCGGTC 780
GTGCGTGTGT CGCGTTGGCT GGGCCGGCAA CGGGATCCTC TGTGGTCGCG ACACTGACCT 840
AGACGGCTTC CCGGACGAGA AGCTGCGCTG CCCGGAGCCG CAGTGCCGTA AGGACAACTG 900 CGTGACTGTG CCCAACTCAG GGCAGGAGGA TGTGGACCGC GATGGCATCG GAGACGCCTG 960
CGATCCGGAT GCCGACGGGG ACGGGGTCCC CAATGAAAAG GACAACTGCC CGCTGGTGCG 1020
GAACCCAGAC CAGCGCAACA CGGACGAGGA CAAGTGGGGC GATGCGTGCG ACAACTGCCG 1080
GTCCCAGAAG AACGACGACC AAAAGGACAC AGACCAGGAC GGCCGGGGCG ATGCGTGCGA 1140
CGACGACATC GACGGCGACC GGATCCGCAA CCAGGCCGAC AACTGCCCTA GGGTACCCAA 1200
CTCAGACCAG AAGGACAGTG ATGGCGATGG TATAGGGGAT GCCTGTGACA ACTGTCCCCA 1260
GAAGAGCAAC CCGGATCAGG CGGATGTGGA CCACGACTTT GTGGGAGATG CTTGTGACAG 1320
CGATCAAGAC CAGGATGGAG ACGGACATCA GGACTCTCGG GACAACTGTC CCACGGTGCC 1380
TAACAGTGCC CAGGAGGACT CAGACCACGA TGGCCAGGGT GATGCCTGCG ACGACGACGA 1440
CGACAATGAC GGAGTCCCTG ACAGTCGGGA CAACTGCCGC CTGGTGCCTA ACCCCGGCCA 1500
GGAGGACGCG GACAGGGACG GCGTGGGCGA CGTGTGCCAG GACGACTTTG ATGCAGACAA 1560
GGTGGTAGAC AAGATCGACG TGTGTCCGGA GAACGCTGAA GTCACGCTCA CCGACTTCAG 1620
GGCCTTCCAG ACAGTCGTGC TGGACCCGGA GGGTGACGCG CAGATTGACC CCAACTGGGT 1680
GGTGCTCAAC CAGGGAAGGG AGATCGTGCA GACAATGAAC AGCGACCCAG GCCTGGCTGT 1740
GGGTTACACT GCCTTCAATG GCGTGGACTT CGAGGGCACG TTCCATGTGA ACACGGTCAC 1800
GGATGACGAC TATGCGGGCT TCATCTTTGG CTACCAGGAC AGCTCCAGCT TCTACGTGGT 1860
CATGTGGAAG CAGATGGAGC AAACGTATTG GCAGGCGAAC CCCTTCCGTG CTGTGGCCGA 1920
GCCTGGCATC CAACTCAAGG CTGTGAAGTC TTCCACAGGC CCCGGGGAAC AGCTGCGGAA 1980
CGCTCTGTGG CATACAGGAG ACACAGAGTC CCAGGTGCGG CTGCTGTGGA AGGACCCGCG 2040
AAACGTGGGT TGGAAGGACA AGAAGTCCTA TCGTTGGTTC CTGCAGCACC GGCCCCAAGT 2100
GGGCTACATC AGGGTGCGAT TCTATGAGGG CCCTGAGCTG GTGGCCGACA GCAACGTGGT 2160
CTTGGACACA ACCATGCGGG GTGGCCGCCT GGGGGTCTTC TGCTTCTCCC AGGAGAACAT 2220
CATCTGGGCC AACCTGCGTT ACCGCTGCAA TGACACCATC CCAGAGGACT ATGAGACCCA 2280
TCAGCTGCGG CAAGCCTAGG GACCAGGGTG AGGACCCGCC GGATGACAGC CACCCTCACC 2340
GCGGCTGGAT GGGGGCTCTG CACCCAGCCC AAGGGGTGGC CGTCCTGAGG GGGAAGTGAG 2400 AAGGGCTCAG AGAGGACAAA ATAAAGTGTG TGTGCAGGG
Seq ID NO: 46 Protein sequence Protein Accession tf: NP_000086.1
1 11 21 31 41 51
I I I I I I
MVPDTACVLL LTLAALGASG QGQSPLGSDL GPQMLRELQE TNAALQDVRD WLRQQVREIT 60
FLKNTVMECD ACGMQQSVRT GLPSVRPLLH CAPGFCFPGV ACIQTESGGR CGPCPAGFTG 120
NGSHCTDVNE CNAHPCFPRV RCINTSPGFR CEACPPGYSG PTHQGVGLAF AKANKQVCTD 180
INECETGQHN CVPNSVCINT RGSFQCGPCQ PGFVGDQASG CQRGAQRFCP DGSPSECHEH 240
ADCVLERDGS RSCVCRVGWA GNGILCGRDT DLDGFPDEKL RCPEPQCRKD NCVTVPNSGQ 300
EDVDRDGIGD ACDPDADGDG VPNEKDNCPL VRNPDQRNTD EDKWGDACDN CRSQKNDDQK 360
DTDQDGRGDA CDDDIDGDRI RNQADNCPRV PNSDQKDSDG DGIGDACDNC PQKSNPDQAD 420
VDHDFVGDAC DSDQDQDGDG HQDSRDNCPT VPNSAQEDSD HDGQGDACDD DDDNDGVPDS 480
RDNCRLVPNP GQEDADRDGV GDVCQDDFDA DKWDKIDVC PENAEVTLTD FRAFQTWLD 540
PEGDAQIDPN WWLNQGREI VQTMNSDPGL AVGYTAFNGV DFEGTFHVNT VTDDDYAGFI 600
FGYQDΞSSFY WMWKQMEQT YWQANPFRAV AEPGIQLKAV KSSTGPGEQL RNALWHTGDT 660
ESQVRLLWKD PRNVGWKDKK SYRWFLQHRP QVGYIRVRFY EGPELVADSN WLDTTMRGG 720 RLGVFCFSQE NIIWANLRYR CNDTIPEDYE THQLRQA
Seq ID NO: 47 DNA sequence
Nucleic Acid Accession tf: NM_001565.1
Coding sequence: 67..363
1 11 21 31 41 51
I I I I I I
GAGACATTCC TCAATTGCTT AGACATATTC TGAGCCTACA GCAGAGGAAC CTCCAGTCTC 60
AGCACCATGA ATCAAACTGC GATTCTGATT TGCTGCCTTA TCTTTCTGAC TCTAAGTGGC 120
ATTCAAGGAG TACCTCTCTC TAGAACCGTA CGCTGTACCT GCATCAGCAT TAGTAATCAA 180
CCTGTTAATC CAAGGTCTTT AGAAAAACTT GAAATTATTC CTGGAAGCCA ATTTTGTCCA 240
CGTGTTGAGA TCATTGCTAC AATGAAAAAG AAGGGTGAGA AGAGATGTCT GAATCCAGAA 300
TCGAAGGCCA TCAAGAATTT ACTGAAAGCA GTTAGCAAGG AAATGTCTAA AAGATCTCCT 360
TAAAACCAGA GGGGAGCAAA ATCGATGCAG TGCTTCCAAG GATGGACCAC ACAGAGGCTG 420
CCTCTCCCAT CACTTCCCTA CATGGAGTAT ATGTCAAGCC ATAATTGTTC TTAGTTTGCA 480
GTTACACTAA AAGGTGACCA ATGATGGTCA CCAAATCAGC TGCTACTACT CCTGTAGGAA 540
GGTTAATGTT CATCATCCTA AGCTATTCAG TAATAACTCT ACCCTGGCAC TATAATGTAA 600
GCTCTACTGA GGTGCTATGT TCTTAGTGGA TGTTCTGACC CTGCTTCAAA TATTTCCCTC 660
ACCTTTCCCA TCTTCCAAGG GTACTAAGGA ATCTTTCTGC TTTGGGGTTT ATCAGAATTC 720
TCAGAATCTC AAATAACTAA AAGGTATGCA ATCAAATCTG CTTTTTAAAG AATGCTCTTT 780
ACTTCATGGA CTTCCACTGC CATCCTCCCA AGGGGCCCAA ATTCTTTCAG TGGCTACCTA 840
CATACAATTC CAAACACATA CAGGAAGGTA GAAATATCTG AAAATGTATG TGTAAGTATT 900
CTTATTTAAT GAAAGACTGT ACAAAGTATA AGTCTTAGAT GTATATATTT CCTATATTGT 960
TTTCAGTGTA CATGGAATAA CATGTAATTA AGTACTATGT ATCAATGAGT AACAGGAAAA 1020
TTTTAAAAAT ACAGATAGAT ATATGCTCTG CATGTTACAT AAGATAAATG TGCTGAATGG 1080 TTTTCAAATA AAAATGAGGT ACTCTCCTGG AAATATTAAG
Seq ID NO: 48 Protein sequence Protein Accession tf: NP_001556.1
1 11 21 31 41 51
I I I I I I
MNQTAILICC LIFLTLSGIQ GVPLSRTVRC TCISISNQPV NPRSLEKLEI IPASQFCPRV 60 EIIATMKKKG EKRCLNPESK AIKNLLKAVS KEMSKRSP
Seq ID NO: 49 DNA sequence
Nucleic Acid Accession ft: XM_057014
Coding sequence: 143..874 1 11 21 31 41 51 1 1 1 1 1 1 | 1 1 1 GGGAGGGAGA GAGGCGCGCG GGTGAAAGGC GCATTGATGC AGCCTGCGGC GGCCTCGGAG 60
CGCGGCGGAG CCAGACGCTG ACCACGTTCC TCTCCTCGGT CTCCTCCGCC TCCAGCTCCG 120
CGCTGCCCGG CAGCCGGGAG CCATGCGACC CCAGGGCCCC GCCGCCTCCC CGCAGCGGCT 180
CCGCGGCCTC CTGCTGCTCC TGCTGCTGCA GCTGCCCGCG CCGTCGAGCG CCTCTGAGAT 240
CCCCAAGGGG AAGCAAAAGG CGCAGCTCCG GCAGAGGGAG GTGGTGGACC TGTATAATGG 300
AATGTGCTTA CAAGGGCCAG CAGGAGTGCC TGGTCGAGAC GGGAGCCCTG GGGCCAATGG 360
CATTCCGGGT ACACCTGGGA TCCCAGGTCG GGATGGATTC AAAGGAGAAA AGGGGGAATG 420
TCTGAGGGAA AGCTTTGAGG AGTCCTGGAC ACCCAACTAC AAGCAGTGTT CATGGAGTTC 480
ATTGAATTAT GGCATAGATC TTGGGAAAAT TGCGGAGTGT ACATTTACAA AGATGCGTTC 540
AAATAGTGCT CTAAGAGTTT TGTTCAGTGG CTCACTTCGG CTAAAATGCA GAAATGCATG 600
CTGTCAGCGT TGGTATTTCA CATTCAATGG AGCTGAATGT TCAGGACCTC TTCCCATTGA 660
AGCTATAATT TATTTGGACC AAGGAAGCCC TGAAATGAAT TCAACAATTA ATATTCATCG 720
CACTTCTTCT GTGGAAGGAC TTTGTGAAGG AATTGGTGCT GGATTAGTGG ATGTTGCTAT 780
CTGGGTTGGC ACTTGTTCAG ATTACCCAAA AGGAGATGCT TCTACTGGAT GGAATTCAGT 840
TTCTCGCATC ATTATTGAAG AACTACCAAA ATAAATGCTT TAATTTTCAT TTGCTACCTC 900
TTTTTTTATT ATGCCTTGGA ATGGTTCACT TAAATGACAT TTTAAATAAG TTTATGTATA 960
CATCTGAATG AAAAGCAAAG CTAAATATGT TTACAGACCA AAGTGTGATT TCACACTGTT 1020
TTTAAATCTA GCATTATTCA TTTTGCTTCA ATCAAAAGTG GTTTCAATAT TTTTTTTAGT 1080
TGGTTAGAAT ACTTTCTTCA TAGTCACATT CTCTCAACCT ATAATTTGGA ATATTGTTGT 1140
GGTCTTTTGT TTTTTCTCTT AGTATAGCAT TTTTAAAAAA ATATAAAAGC TACCAATCTT 1200
TGTACAATTT GTAAATGTTA AGAATTTTTT TTATATCTGT TAAATAAAAA TTATTTCCAA 1260
CAACCTTAAA AAAAAAAAAA AAAA
Seq ID NO: 50 Protein sequence
Protein Accession #: XP 057014
1 11 21 31 41 51
I I I I I I
MRPQGPAASP QRLRGLLLLL LLQLPAPSSA SEIPKGKQKA QLRQREWDL YNGMCLQGPA 60
GVPGRDGSPG ANGIPGTPGI PGRDGFKGEK GECLRESFEE SWTPNYKQCS WSSLNYGIDL 120
GKIAECTFTK MRSNSALRVL FSGSLRLKCR NACCQRWYFT FNGAECSGPL PIEAIIYLDQ 180
GSPEMNSTIN IHRTSSVEGL CEGIGAGLVD VAIWVGTCSD YPKGDASTGW NSVSRIIIEE 240
LPK
Seq ID NO: 51 DNA sequence
Nucleic Acid Accession #: NM.020974
Coding sequence: 81..3080
11 21 31 51
I
GGCGTCCGCG CACACCTCCC CGCGCCGCCG CCGCCACCGC CCGCACTCCG CCGCCTCTGC 60
CCGCAACCGC TGAGCCATCC ATGGGGGTCG CGGGCCGCAA CCGTCCCGGG GCGGCCTGGG 120
CGGTGCTGCT GCTGCTGCTG CTGCTGCCGC CACTGCTGCT GCTGGCGGGG GCCGTCCCGC 180
CGGGTCGGGG CCGTGCCGCG GGGCCGCAGG AGGATGTAGA TGAGTGTGCC CAAGGGCTAG 240
ATGACTGCCA TGCCGACGCC CTGTGTCAGA ACACACCCAC CTCCTACAAG TGCTCCTGCA 300
AGCCTGGCTA CCAAGGGGAA GGCAGGCAGT GTGAGGACAT CGATGAATGT GGAAATGAGC 360
TCAATGGAGG CTGTGTCCAT GACTGTTTGA ATATTCCAGG CAATTATCGT TGCACTTGTT 420
TTGATGGCTT CATGTTGGCT CATGACGGTC ATAATTGTCT TGATGTGGAC GAGTGCCTGG 480
AGAACAATGG CGGCTGCCAG CATACCTGTG TCAACGTCAT GGGGAGCTAT GAGTGCTGCT 540
GCAAGGAGGG GTTTTTCCTG AGTGACAATC AGCACACCTG CATTCACCGC TCGGAAGAGG 600
GCCTGAGCTG CATGAATAAG GATCACGGCT GTAGTCACAT CTGCAAGGAG GCCCCAAGGG 660
GCAGCGTCGC CTGTGAGTGC AGGCCTGGTT TTGAGCTGGC CAAGAACCAG AGAGACTGCA 720
TCTTGACCTG TAACCATGGG AACGGTGGGT GCCAGCACTC CTGTGACGAT ACAGCCGATG 780
GCCCAGAGTG CAGCTGCCAT CCACAGTACA AGATGCACAC AGATGGGAGG AGCTGCCTTG 840
AGCGAGAGGA CACTGTCCTG GAGGTGACAG AGAGCAACAC CACATCAGTG GTGGATGGGG 900
ATAAACGGGT GAAACGGCGG CTGCTCATGG AAACGTGTGC TGTCAACAAT GGAGGCTGTG 960
ACCGCACCTG TAAGGATACT TCGACAGGTG TCCACTGCAG TTGTCCTGTT GGATTCACTC 1020
TCCAGTTGGA TGGGAAGACA TGTAAAGATA TTGATGAGTG CCAGACCCGC AATGGAGGTT 1080
GTGATCATTT CTGCAAAAAC ATCGTGGGCA GTTTTGACTG CGGCTGCAAG AAAGGATTTA 1140
AATTATTAAC AGATGAGAAG TCTTGCCAAG ATGTGGATGA GTGCTCTTTG GATAGGACCT 1200
GTGACCACAG CTGCATCAAC CACCCTGGCA CATTTGCTTG TGCTTGCAAC CGAGGGTACA 1260
CCCTGTATGG CTTCACCCAC TGTGGAGACA CCAATGAGTG CAGCATCAAC AACGGAGGCT 1320
GTCAGCAGGT CTGTGTGAAC ACAGTGGGCA GCTATGAATG CCAGTGCCAC CCTGGGTACA 1380
AGCTCCACTG GAATAAAAAA GACTGTGTGG AAGTGAAGGG GCTCCTGCCC ACAAGTGTGT 1440
CACCCCGTGT GTCCCTGCAC TGCGGTAAGA GTGGTGGAGG AGACGGGTGC TTCCTCAGAT 1500
GTCACTCTGG CATTCACCTC TCTTCAGATG TCACCACCAT CAGGACAAGT GTAACCTTTA 1560
AGCTAAATGA AGGCAAGTGT AGTTTGAAAA ATGCTGAGCT GTTTCCCGAG GGTCTGCGAC 1620
CAGCACTACC AGAGAAGCAC AGCTCAGTAA AAGAGAGCTT CCGCTACGTA AACCTTACAT 1680
GCAGCTCTGG CAAGCAAGTC CCAGGAGCCC CTGGCCGACC AAGCACCCCT AAGGAAATGT 1740
TTATCACTGT TGAGTTTGAG CTTGAAACTA ACCAAAAGGA GGTGACAGCT TCTTGTGACC 1800
TGAGCTGCAT CGTAAAGCGA ACCGAGAAGC GGCTCCGTAA AGCCATCCGC ACGCTCAGAA 1860
AGGCCGTCCA CAGGGAGCAG TTTCACCTCC AGCTCTCAGG CATGAACCTC GACGTGGCTA 1920
AAAAGCCTCC CAGAACATCT GAACGCCAGG CAGAGTCCTG TGGAGTGGGC CAGGGTCATG 1980
CAGAAAACCA ATGTGTCAGT TGCAGGGCTG GGACCTATTA TGATGGAGCA CGAGAACGCT 2040
GCATTTTATG TCCAAATGGA ACCTTCCAAA ATGAGGAAGG ACAAATGACT TGTGAACCAT 2100
GCCCAAGACC AGGAAATTCT GGGGCCCTGA AGACCCCAGA AGCTTGGAAT ATGTCTGAAT 2160
GTGGAGGTCT GTGTCAACCT GGTGAATATT CTGCAGATGG CTTTGCACCT TGCCAGCTCT 2220
GTGCCCTGGG CACGTTCCAG CCTGAAGCTG GTCGAACTTC CTGCTTCCCC TGTGGAGGAG 2280
GCCTTGCCAC CAAACATCAG GGAGCTACTT CCTTTCAGGA CTGTGAAACC AGAGTTCAAT 2340
GTTCACCTGG ACATTTCTAC AACACCACCA . CTCACCGATG TATTCGTTGC CCAGTGGGAA 2400
CATACCAGCC TGAATTTGGA AAAAATAATT GTGTTTCTTG CCCAGGAAAT ACTACGACTG 2460
ACTTTGATGG CTCCACAAAC ATAACCCAGT GTAAAAACAG AAGATGTGGA GGGGAGCTGG 2520 GAGATTTCAC TGGGTACATT GAATCCCCAA ACTACCCAGG CAATTACCCA GCCAACACCG 2580 AGTGTACGTG GACCATCAAC CCACCCCCCA AGCGCCGCAT CCTGATCGTG GTCCCTGAGA 2640 TCTTCCTGCC CATAGAGGAC GACTGTGGGG ACTATCTGGT GATGCGGAAA ACCTCTTCAT 2700 CCAATTCTGT GACAACATAT GAAACCTGCC AGACCTACGA ACGCCCCATC GCCTTCACCT 2760 CCAGGTCAAA GAAGCTGTGG ATTCAGTTCA AGTCCAATGA AGGGAACAGC GCTAGAGGGT 2820 TCCAGGTCCC ATACGTGACA TATGATGAGG ACTACCAGGA ACTCATTGAA GACATAGTTC 2880 GAGATGGCAG GCTCTATGCA TCTGAGAACC ATCAGGAAAT ACTTAAGGAT AAGAAACTTA 2940 TCAAGGCTCT GTTTGATGTC CTGGCCCATC CCCAGAACTA TTTCAAGTAC ACAGCCCAGG 3000 AGTCCCGAGA GATGTTTCCA AGATCGTTCA TCCGATTGCT ACGTTCCAAA GTGTCCAGGT 3060 TTTTGAGACC TTACAAATGA CTCAGCCCAC GTGCCACTCA ATACAAATGT TCTGCTATAG 3120 GGTTGGTGGG ACAGAGCTGT CTTCCTTCTG CATGTCAGCA CAGTCGGGTA TTGCTGCCTC 3180 CCGTATCAGT GACTCATTAG AGTTCAATTT TTATAGATAA TACAGATATT TTGGTAAATT 3240 GAACTTGGTT TTTCTTTCCC AGCATCGTGG ATGTAGACTG AGAATGGCTT TGAGTGGCAT 3300 CAGCTTCTCA CTGCTGTGGG CGGATGTCTT GGATAGATCA CGGGCTGGCT GAGCTGGACT 3360 TTGGTCAGCC TAGGTGAGAC TCACCTGTCC TTCTGGGGTC TTACTCCTCC TCAAGGAGTC 3420 TGTAGTGGAA AGGAGGCCAC AGAATAAGCT GCTTATTCTG AAACTTCAGC TTCCTCTAGC 3480 CCGGCCCTCT CTAAGGGAGC CCTCTGCACT CGTGTGCAGG CTCTGACCAG GCAGAACAGG 3540 CAAGAGGGGA GGGAAGGAGA CCCCTGCAGG CTCCCTCCAC CCACCTTGAG ACCTGGGAGG 3600 ACTCAGTTTC TCCACAGCCT TCTCCAGCCT GTGTGATACA AGTTTGATCC CAGGAACTTG 3660 AGTTCTAAGC AGTGCTCGTG AAAAAAAAAA GCAGAAAGAA TTAGAAATAA ATAAAAACTA 3720 AGCACTTCTG GAGACAT
Seq ID NO: 52 Protein sequence Protein Accession it: NP 066025
11 21 31 41 51
I I I I
MGVAGRNRPG AAWAVLLLLL LLPPLLLLAG AVPPGRGRAA GPQEDVDECA QGLDDCHADA 60 LCQNTPTSYK CSCKPGYQGE GRQCEDIDEC GNELNGGCVH DCLNIPGNYR CTCFDGFMLA 120 HDGHNCLDVD ECLENNGGCQ HTCVNVMGSY ECCCKEGFFL SDNQHTCIHR SEEGLSCMNK 180 DHGCSHICKE APRGSVACEC RPGFELAKNQ RDCILTCNHG NGGCQHSCDD TADGPECSCH 240 PQYKMHTDGR SCLEREDTVL EVTESNTTSV VDGDKRVKRR LLMETCAVNN GGCDRTCKDT 300 STGVHCSCPV GFTLQLDGKT CKDIDECQTR NGGCDHFCKN IVGSFDCGCK KGFKLLTDEK 360 SCQDVDECΞL DRTCDHSCIN HPGTFACACN RGYTLYGFTH CGDTNECSIN NGGCQQVCVN 420 TVGSYECQCH PGYKLHWNKK DCVEVKGLLP TSVSPRVSLH CGKSGGGDGC FLRCHSGIHL 480 SSDVTTIRTS VTFKLNEGKC SLKNAELFPE GLRPALPEKH SSVKESFRYV NLTCSSGKQV 540 PGAPGRPSTP KEMFITVEFE LETNQKEVTA SCDLSCIVKR TEKRLRKAIR TLRKAVHREQ 600 FHLQLSGMNL DVAKKPPRTS ERQAESCGVG QGHAENQCVS CRAGTYYDGA RERCILCPNG 660 TFQNEEGQMT CEPCPRPGNS GALKTPEAWN MSECGGLCQP GEYSADGFAP CQLCALGTFQ 720 PEAGRTSCFP CGGGLATKHQ GATSFQDCET RVQCSPGHFY NTTTHRCIRC PVGTYQPEFG 780 KNNCVSCPGN TTTDFDGSTN ITQCKNRRCG GELGDFTGYI ESPNYPGNYP ANTECTWTIN 840 PPPKRRILIV VPEIFLPIED DCGDYLVMRK TSSSNSVTTY ETCQTYERPI AFTSRSKKLW 900 IQFKSNEGNS ARGFQVPYVT YDEDYQELIE DIVRDGRLYA SENHQEILKD KKLIKALFDV 960 LAHPQNYFKY TAQESREMFP RSFIRLLRSK VSRFLRPYK
Seq ID NO: 53 DNA sequence
Nucleic Acid Accession #: NM_014211
Coding sequence: 157..1479
11 21 31 41 51
I I I I I
GGGACAGGGC TGAGGATGAG GAGAACCCTG GGGACCCAGA AGACCGTGCC TTGCCCGGAA 60 GTCCTGCCTG TAGGCCTGAA GGACTTGCCC TAACAGAGCC TCAACAACTA CCTGGTGATT 120 CCTACTTCAG CCCCTTGGTG TGAGCAGCTT CTCAACATGA ACTACAGCCT CCACTTGGCC 180 TTCGTGTGTC TGAGTCTCTT CACTGAGAGG ATGTGCATCC AGGGGAGTCA GTTCAACGTC 240 GAGGTGGGCA GAAGTGACAA GCTTTCCCTG CCTGGCTTTG AGAACCTCAC AGCAGGATAT 300 AACAAATTTC TCAGGCCCAA TTTTGGTGGA GAACCCGTAC AGATAGCGCT GACTCTGGAC 360 ATTGCAAGTA TCTCTAGCAT TTCAGAGAGT AACATGGACT ACACAGCCAC CATATACCTC 420 CGACAGCGCT GGATGGACCA GCGGCTGGTG TTTGAAGGCA ACAAGAGCTT CACTCTGGAT 480 GCCCGCCTCG TGGAGTTCCT CTGGGTGCCA GATACTTACA TTGTGGAGTC CAAGAAGTCC 540 TTCCTCCATG AAGTCACTGT GGGAAACAGG CTCATCCGCC TCTTCTCCAA TGGCACGGTC 600 CTGTATGCCC TCAGAATCAC GACAACTGTT GCATGTAACA TGGATCTGTC TAAATACCCC 660 ATGGACACAC AGACATGCAA GTTGCAGCTG GAAAGCTGGG GCTATGATGG AAATGATGTG 720 GAGTTCACCT GGCTGAGAGG GAACGACTCT GTGCGTGGAC TGGAACACCT GCGGCTTGCT 780 CAGTACACCA TAGAGCGGTA TTTCACCTTA GTCACCAGAT CGCAGCAGGA GACAGGAAAT 840 TACACTAGAT TGGTCTTACA GTTTGAGCTT CGGAGGAATG TTCTGTATTT CATTTTGGAA 900 ACCTACGTTC CTTCCACTTT CCTGGTGGTG TTGTCCTGGG TTTCATTTTG GATCTCTCTC 960 GATTCAGTCC CTGCAAGAAC CTGCATTGGA GTGACGACCG TGTTATCAAT GACCACACTG 1020 ATGATCGGGT CCCGCACTTC TCTTCCCAAC ACCAACTGCT TCATCAAGGC CATCGATGTG 1080 TACCTGGGGA TCTGCTTTAG CTTTGTGTTT GGGGCCTTGC TAGAATATGC AGTTGCTCAC 1140 TACAGTTCCT TACAGCAGAT GGCAGCCAAA GATAGGGGGA CAACAAAGGA AGTAGAAGAA 1200 GTCAGTATTA CTAATATCAT CAACAGCTCC ATCTCCAGCT TTAAACGGAA GATCAGCTTT 1260 GCCAGCATTG AAATTTCCAG CGACAACGTT GACTACAGTG ACTTGACAAT GAAAACCAGC 1320 GACAAGTTCA AGTTTGTCTT CCGAGAAAAG ATGGGCAGGA TTGTTGATTA TTTCACAATT 1380 CAAAACCCCA GTAATGTTGA TCACTATTCC AAACTACTGT TTCCTTTGAT TTTTATGCTA 1440 GCCAATGTAT TTTACTGGGC ATACTACATG TATTTTTGAG TCAATGTTAA ATTTCTTGCA 1500 TGCCATAGGT CTTCAACAGG ACAAGATAAT GATGTAAATG GTATTTTAGG CCAAGTGTGC 1560 ACCCACATCC AATGGTGCTA CAAGTGACTG AAATAATATT TGAGTCTTTC TGCTCAAAGA 1620 ATGAAGCTCC AACCATTGTT CTAAGCTGTG TAGAAGTCCT AGCATTATAG GATCTTGTAA 1680 TAGAAACATC AGTCCATTCC TCTTTCATCT TAATCAAGGA CATTCCCATG GAGCCCAAGA 1740 TTACAAATGT ACTCAGGGCT GTTTATTCGG TGGCTCCCTG GTTTGCATTT ACCTCATATA 1800 AAGAATGGGA AGGAGACCAT TGGGTAACCC TCAAGTGTCA GAAGTTGTTT CTAAAGTAAC 1860 TATACATGTT TTTTACTAAA TCTCTGCAGT GCTTATAAAA TACATTGTTG CCTATTTAGG 1920 GAGTAACATT TTCTAGTTTT TGTTTCTGGT TAAAATGAAA TATGGGCTTA TGTCAATTCA 1980 TTGGAAGTCA ATGCACTAAC TCAATACCAA GATGAGTTTT TAAATAATGA ATATTATTTA 2040 ATACCACAAC AGAATTATCC CCAATTTCCA ATAAGTCCTA TCATTGAAAA TTCAAATATA 2100 AGTGAAGAAA AAATTAGTAG ATCAACAATC TAAACAAATC CCTCGGTTCT AAGATACAAT 2160 GGATTCCCCA TACTGGAAGG ACTCTGAGGC TTTATTCCCC CACTATGCAT ATCTTATCAT 2220 TTTATTATTA TACACACATC CATCCTAAAC TATACTAAAG CCCTTTTCCC ATGCATGGAT 2280 GGAAATGGAA GATTTTTTTG TAACTTGTTC TAGAAGTCTT AATATGGGCT GTTGCCATGA 2340 AGGCTTGCAG AATTGAGTCC ATTTTCTAGC TGCCTTTATT CACATAGTGA TGGGGTACTA 2400 AAAGTACTGβ GTTGACTCAG AGAGTCGCTG TCATTCTGTC ATTGCTGCTA CTCTAACACT 2460 GAGCAACACT CTCCCAGTGG CAGATCCCCT GTATCATTCC AAGAGGAGCA TTCATCCCTT 2520 TGCTCTAATG ATCAGGAATG ATGCTTATTA GAAAACAAAC TGCTTGACCC AGGAACAAGT 2580 GGCTTAGCTT AAGTAAACTT GGCTTTGCTC AGATCCCTGA TCCTTCCAGC TGGTCTGCTC 2640 TGAGTGGCTT ATCCCGCATG AGCAGGAGCG TGCTGGCCCT GAGTACTGAA CTTTCTGAGT 2700 AACAATGAGA CACGTTACAG AACCTATGTT CAGGTTGCGG GTGAGCTGCC CTCTCCAAAT 2760 CCAGCCAGAβ ATGCACATTC CTCGGCCAGT CTCAGCCAAC AGTACCAAAA GTGATTTTTG 2820 AGTGTGCCAβ GGTAAAGGCT TCCAGTTCAG CCTCAGTTAT TTTAGACAAT CTCGCCATCT 2880 TTAATTTCTT AGCTTCCTGT TCTAATAAAT GCACGGCTTT ACCTTTCCTG TCAGAAATAA 2940 ACCAAGGCTC TAAAAGATGA TTTCCCTTCT GTAACTCCCT AGAGCCACAG GTTCTCATTC 3000 CTTTTCCCAT TATACTTCTC ACAATTCAGT TTCTATGAGT TTGATCACCT GATTTTTTTA 3060 ACAAAATATT TCTAACGGGA ATGGGTGGGA GTGCTGGTGA AAAGAGATGA AATGTGGTTG 3120 TATGAGCCAA TCATATTTGT GATTTTTTAA AAAAAGTTTA AAAGGAAATA TCTGTTCTGA 3180 AACCCCACTT AAGCATTGTT TTTATATAAA AACAATGATA AAGATGTGAA CTGTGAAATA 3240 AATATACCAT ATTAGCTACC CACC
Seq ID NO: 54 Protein sequence Protein Accession ft: NP 055026
11 21 31 41 51
I I I I I
MNYSLHLAFV CLSLFTERMC IQGSQFNVEV GRSDKLSLPG FENLTAGYNK FLRPNFGGEP 60 VQIALTLDIA SISSISESNM DYTATIYLRQ RWMDQRLVFE GNKSFTLDAR LVEFLWVPDT 120 YIVESKKSFL HEVTVGNRLI RLFSNGTVLY ALRITTTVAC NMDLSKYPMD TQTCKLQLES 180 WGYDGNDVEF TWLRGNDSVR GLEHLRLAQY TIERYFTLVT RSQQETGNYT RLVLQFELRR 240 NVLYFILETY VPSTFLWLS WVSFWISLDS VPARTCIGVT TVLSMTTLMI GSRTSLPNTN 300 CFIKAIDVYL GICFSFVFGA LLEYAVAHYS SLQQMAAKDR GTTKEVEEVS ITNIINSSIS 360 SFKRKISFAS IEISSDNVDY SDLTMKTSDK FKFVFREKMG RIVDYFTIQN PSNVDHYSKL 420 LFPLIFMLAN VFYWAYYMYF
Seq ID NO: 55 DNA sequence Nucleic Acid Accession ft: XM_084007 Coding sequence: 138..2405
1 11 21 31 41 51 J 1 | 1 | 1 1 1 11 11
CTCGTGCCGA ATTCGGCACG AGACCGCGTG TTCGCGCCTG GTAGAGATTT CTCGAAGACA 60
CCAGTGGGCC CGTGTGGAAC CAAACCTGCG CGCGTGGCCG GGCCGTGGGA CAACGAGGCC 120
GCGGAGACGA AGGCGCAATG GCGAGGAAGT TATCTGTAAT CTTGATCCTG ACCTTTGCCC 180
TCTCTGTCAC AAATCCCCTT CATGAACTAA AAGCAGCTGC TTTCCCCCAG ACCACTGAGA 240
AAATTAGTCC GAATTGGGAA TCTGGCATTA ATGTTGACTT GGCAATTTCC ACACGGCAAT 300
ATCATCTACA ACAGCTTTTC TACCGCTATG GAGAAAATAA TTCTTTGTCA GTTGAAGGGT 360
TCAGAAAATT ACTTCAAAAT ATAGGCATAG ATAAGATTAA AAGAATCCAT ATACACCATG 420
ACCACGACCA TCACTCAGAC CACGAGCATC ACTCAGACCA TGAGCGTCAC TCAGACCATG 480
AGCATCACTC AGACCACGAG CATCACTCTG ACCATGATCA TCACTCCCAC CATAATCATG 540
CTGCTTCTGG TAAAAATAAG CGAAAAGCTC TTTGCCCAGA CCATGACTCA GATAGTTCAG 600
GTAAAGATCC TAGAAACAGC CAGGGGAAAG GAGCTCACCG ACCAGAACAT GCCAGTGGTA 660
GAAGGAATGT CAAGGACAGT GTTAGTGCTA GTGAAGTGAC CTCAACTGTG TACAACACTG 720
TCTCTGAAGG AACTCACTTT CTAGAGACAA TAGAGACTCC AAGACCTGGA AAACTCTTCC 780
CCAAAGATGT AAGCAGCTCC ACTCCACCCA GTGTCACATC AAAGAGCCGG GTGAGCCGGC 840
TGGCTGGTAG GAAAACAAAT GAATCTGTGA GTGAGCCCCG AAAAGGCTTT ATGTATTCCA 900
GAAACACAAA TGAAAATCCT CAGGAGTGTT TCAATGCATC AAAGCTACTG ACATCTCATG 960
GCATGGGCAT CCAGGTTCCG CTGAATGCAA CAGAGTTCAA CTATCTCTGT CCAGCCATCA 1020
TCAACCAAAT TGATGCTAGA TCTTGTCTGA TTCATACAAG TGAAAAGAAG GCTGAAATCC 1080
CTCCAAAGAC CTATTCATTA CAAATAGCCT GGGTTGGTGG TTTTATAGCC ATTTCCATCA 1140
TCAGTTTCCT GTCTCTGCTG GGGGTTATCT TAGTGCCTCT CATGAATCGG GTGTTTTTCA 1200
AATTTCTCCT GAGTTTCCTT GTGGCACTGG CCGTTGGGAC TTTGAGTGGT GATGCTTTTT 1260
TACACCTTCT TCCACATTCT CATGCAAGTC ACCACCATAG TCATAGCCAT GAAGAACCAG 1320
CAATGGAAAT GAAAAGAGGA CCACTTTTCA GTCATCTGTC TTCTCAAAAC ATAGAAGAAA 1380
GTGCCTATTT TGATTCCACG TGGAAGGGTC TAACAGCTCT AGGAGGCCTG TATTTCATGT 1440
TTCTTGTTGA ACATGTCCTC ACATTGATCA AACAATTTAA AGATAAGAAG AAAAAGAATC 1500
AGAAGAAACC TGAAAATGAT GATGATGTGG AGATTAAGAA GCAGTTGTCC AAGTATGAAT 1560
CTCAACTTTC AACAAATGAG GAGAAAGTAG ATACAGATGA TCGAACTGAA GGCTATTTAC 1620
GAGCAGACTC ACAAGAGCCC TCCCACTTTG ATTCTCAGCA GCCTGCAGTC TTGGAAGAAG 1680
AAGAGGTCAT GATAGCTCAT GCTCATCCAC AGGAAGTCTA CAATGAATAT GTACCCAGAG 1740
GGTGCAAGAA TAAATGCCAT TCACATTTCC ACGATACACT CGGCCAGTCA GACGATCTCA 1800
TTCACCACCA TCATGACTAC CATCATATTC TCCATCATCA CCACCACCAA AACCACCATC 1860
CTCACAGTCA CAGCCAGCGC TACTCTCGGG AGGAGCTGAA AGATGCCGGC GTCGCCACTT 1920
TGGCCTGGAT GGTGATAATG GGTGATGGCC TGCACAATTT CAGCGATGGC CTAGCAATTG 1980
GTGCTGCTTT TACTGAAGGC TTATCAAGTG GTTTAAGTAC TTCTGTTGCT GTGTTCTGTC 2040
ATGAGTTGCC TCATGAATTA GGTGACTTTG CTGTTCTACT AAAGGCTGGC ATGACCGTTA 2100
AGCAGGCTGT CCTTTATAAT GCATTGTCAG CCATGCTGGC GTATCTTGGA ATGGCAACAG 2160
GAATTTTCAT TGGTCATTAT GCTGAAAATG TTTCTATGTG GATATTTGCA CTTACTGCTG 2220
GCTTATTCAT GTATGTTGCT CTGGTTGATA TGGTACCTGA AATGCTGCAC AATGATGCTA 2280
GTGACCATGG ATGTAGCCGC TGGGGGTATT TCTTTTTACA GAATGCTGGG ATGCTTTTGG 2340
GTTTTGGAAT TATGTTACTT ATTTCCATAT TTGAACATAA AATCGTGTTT CGTATAAATT 2400
TCTAGTTAAG GTTTAAATGC TAGAGTAGCT TAAAAAGTTG TCATAGTTTC AGTAGGTCAT 2460 AGGGAGATGA GTTTGTATGC TGTACTATGC AGCGTTTAAA GTTAGTGGGT TTTGTGATTT 2520 TTGTATTGAA TATTGCTGTC TGTTACAAAG TCAGTTAAAG GTACGTTTTA ATATTTAAGT 2580 TATTCTATCT TGGAGATAAA ATCTGTATGT GCAATTCACC GGTATTACCA GTTTATTATG 2640 TAAACAAGAG ATTTGGCATG ACATGTTCTG TATGTTTCAG GGAAAAATGT CTTTAATGCT 2700 TTTTCAAGAA CTAACACAGT TATTCCTATA CTGGATTTTA GGTCTCTGAA GAACTGCTGG 2760 TGTTTAGGAA TAAGAATGTG CATGAAGCCT AAAATACCAA GAAAGCTTAT ACTGAATTTA 2820 AGCAAAGAAA TAAAGGAGAA AAGAGAAGAA TCTGAGAATT GGGGAGGCAT AGATTCTTAT 2880 AAAAATCACA AAATTTGTTG TAAATTAGAG GGGAGAAATT TAGAATTAAG TATAAAAAGG 2940 CAGAATTAGT ATAGAGTACA TTCATTAAAC ATTTTTGTCA GGATTATTTC CCGTAAAAAC 3000 GTAGTGAGCA CTCTCATATA CTAATTAGTG TACATTTAAC TTTGTATAAT ACAGAAATCT 3060 AAATATATTT AATGAATTCA AGCAATATAC ACTTGACCAA GAAATTGGAA TTTCAAAATG 3120 TTCGTGCGGG TTATATACCA GATGAGTACA GTGAGTAGTT TATGTATCAC CAGACTGGGT 3180 TATTGCCAAG TTATATATCA CCAAAAGCTG TATGACTGGA TGTTCTGGTT ACCTGGTTTA 3240 CAAAATTATC AGAGTAGTAA AACTTTGATA TATATGAGGA TATTAAAACT ACACTAAGTA 3300 TCATTTGATT CGATTCAGAA AGTACTTTGA TATCTCTCAG TGCTTCAGTG CTATCATTGT 3360 GAGCAATTGT CTTTATATAC GGTACTGTAG CCATACTAGG CCTGTCTGTG GCATTCTCTA 3420 GATGTTTCTT TTTTACACAA TAAATTCCTT ATATCAGCTT G
Seq ID NO: 56 Protein sequence Protein Accession ft: XP 084007
MARKLSVILI LTFALSVTNP LHELKAAAFP QTTEKISPNW ESGINVDLAI STRQYHLQQL 60
FYRYGENNSL SVEGFRKLLQ NIGIDKIKRI HIHHDHDHHS DHEHHSDHER HSDHEHHSDH 120
EHHSDHDHHS HHNHAASGKN KRKALCPDHD SDSSGKDPRN SQGKGAHRPE HASGRRNVKD 180
SVSASEVTST VYNTVSEGTH FLETIETPRP GKLFPKDVSS STPPSVTSKS RVSRLAGRKT 240
NESVSEPRKG FMYSRNTNEN PQECFNASKL LTSHGMGIQV PLNATEFNYL CPAIINQIDA 300
RSCLIHTSEK KAEIPPKTYS LQIAWVGGFI AISIISFLSL LGVILVPLMN RVFFKFLLSF 360
LVALAVGTLS GDAFLHLLPH SHASHHHSHS HEEPAMEMKR GPLFSHLSSQ NIEESAYFDS 420
TWKGLTALGG LYFMFLVEHV LTLIKQFKDK KKKNQKKPEN DDDVEIKKQL SKYESQLSTN 480
EEKVDTDDRT EGYLRADSQE PSHFDSQQPA VLEEEEVMIA HAHPQEVYNE YVPRGCKNKC 540
HSHFHDTLGQ SDDLIHHHHD YHHILHHHHH QNHHPHSHSQ RYSREELKDA GVATLAWMVI 600
MGDGLHNFSD GLAIGAAFTE GLSSGLSTSV AVFCHELPHE LGDFAVLLKA GMTVKQAVLY 660
NALSAMLAYL GMATGIFIGH YAENVSMWIF ALTAGLFMYV ALVDMVPEML HNDASDHGCS 720
RWGYFFLQNA GMLLGFGIML LISIFEHKIV FRINF
Seq ID NO: 57 DNA sequence
Nucleic Acid Accession ft: NM_015419.1 Coding sequence: 1..8487
CCAT 60
Figure imgf000970_0001
CCAC 120
TGCACGTTCC GATCCCTGGC TTCCGTGCCC GCTGGCATTG CTAGACACGT GGAAAGAATC 180
AATTTGGGGT TTAATAGCAT ACAGGCCCTG TCAGAAACCT CATTTGCAGG ACTGACCAAG 240
TTGGAGCTAC TTATGATTCA CGGCAATGAG ATCCCAAGCA TCCCCGATGG AGCTTTAAGA 300
GACCTCAGCT CTCTTCAGGT TTTCAAGTTC AGCTACAACA AGCTGAGAGT GATCACAGGA 360
CAGACCCTCC AGGGTCTCTC TAACTTAATG AGGCTGCACA TTGACCACAA CAAGATCGAG 420
TTTATCCACC CTCAAGCTTT CAACGGCTTA ACGTCTCTGA GGCTACTCCA TTTGGAAGGA 480
AATCTCCTCC ACCAGCTGCA CCCCAGCACC TTCTCCACGT TCACATTTTT GGATTATTTC 540
AGACTCTCCA CCATAAGGCA CCTCTACTTA GCAGAGAACA TGGTTAGAAC TCTTCCTGCC 600
AGCATGCTTC GGAACATGCC GCTTCTGGAG AATCTTTACT TGCAGGGAAA TCCGTGGACC 660
TGCGATTGTG AGATGAGATG GTTTTTGGAA TGGGATGCAA AATCCAGAGG AATTCTGAAG 720
TGTAAAAAGG ACAAAGCTTA TGAAGGCGGT CAGTTGTGTG CAATGTGCTT CAGTCCAAAG 780
AAGTTGTACA AACATGAGAT ACACAAGCTG AAGGACATGA CTTGTCTGAA GCCTTCAATA 840
GAGTCCCCTC TGAGACAGAA CAGGAGCAGG AGTATTGAGG AGGAGCAAGA ACAGGAAGAG 900
GATGGTGGCA GCCAGCTCAT CCTGGAGAAA TTCCAACTGC CCCAGTGGAG CATCTCTTTG 960
AATATGACCG ACGAGCACGG GAACATGGTG AACTTGGTCT GTGACATCAA GAAACCAATG 1020
GATGTGTACA AGATTCACTT GAACCAAACG GATCCTCCAG ATATTGACAT AAATGCAACA 1080
GTTGCCTTGG ACTTTGAGTG TCCAATGACC CGAGAAAACT ATGAAAAGCT ATGGAAATTG 1140
ATAGCATACT ACAGTGAAGT TCCCGTGAAG CTACACAGAG AGCTCATGCT CAGCAAAGAC 1200
CCCAGAGTCA GCTACCAGTA CAGGCAGGAT GCTGATGAGG AAGCTCTTTA CTACACAGGT 1260
GTGAGAGCCC AGATTCTTGC AGAACCAGAA TGGGTCATGC AGCCATCCAT AGATATCCAG 1320
CTGAACCGAC GTCAGAGTAC GGCCAAGAAG GTGCTACTTT CCTACTACAC CCAGTATTCT 1380
CAAACAATAT CCACCAAAGA TACAAGGCAG GCTCGGGGCA GAAGCTGGGT AATGATTGAG 1440
CCTAGTGGAG CTGTGCAAAG AGATCAGACT GTCCTGGAAG GGGGTCCATG CCAGTTGAGC 1500
TGCAACGTGA AAGCTTCTGA GAGTCCATCT ATCTTCTGGG TGCTTCCAGA TGGCTCCATC 1560
CTGAAAGCGC CCATGGATGA CCCAGACAGC AAGTTCTCCA TTCTCAGCAG TGGCTGGCTG 1620
AGGATCAAGT CCATGGAGCC ATCTGACTCA GGCTTGTACC AGTGCATTGC TCAAGTGAGG 1680
GATGAAATGG ACCGCATGGT ATATAGGGTA CTTGTGCAGT CTCCCTCCAC TCAGCCAGCC 1740
GAGAAAGACA CAGTGACAAT TGGCAAGAAC CCAGGGGAGT CGGTGACATT GCCTTGCAAT 1800
GCTTTAGCAA TACCCGAAGC CCACCTTAGC TGGATTCTTC CAAACAGAAG GATAATTAAT 1860
GATTTGGCTA ACACATCACA TGTATACATG TTGCCAAATG GAACTCTTTC CATCCCAAAG 1920
GTCCAAGTCA GTGATAGTGG TTACTACAGA TGTGTGGCTG TCAACCAGCA AGGGGCAGAC 1980
CATTTTACGG TGGGAATCAC AGTGACCAAG AAAGGGTCTG GCTTGCCATC CAAAAGAGGC 2040
AGACGCCCAG GTGCAAAGGC TCTTTCCAGA GTCAGAGAAG ACATCGTGGA GGATGAAGGG 2100
GGCTCGGGCA TGGGAGATGA AGAGAACACT TCAAGGAGAC TTCTGCATCC AAAGGACCAA 2160
GAGGTGTTCC TCAAAACAAA GGATGATGCC ATCAATGGAG ACAAGAAAGC CAAGAAAGGG 2220
AGAAGAAAGC TGAAACTCTG GAAGCATTCG GAAAAAGAAC CAGAGACCAA TGTTGCAGAA 2280
GGTCGCAGAG TGTTTGAATC TAGACGAAGG ATAAACATGG CAAACAAACA GATTAATCCG 2340
GAGCGCTGGG CTGATATTTT AGCCAAAGTC CGTGGGAAAA ATCTCCCTAA GGGCACAGAA 2400
GTACCCCCGT TGATTAAAAC CACAAGTCCT CCATCCTTGA GCCTAGAAGT CACACCACCT 2460 TTTCCTGCTG TTTCTCCCCC CTCAGCATCT CCTGTGCAGA CAGTAACCAG TGCTGAAGAA 2520
TCCTCAGCAG ATGTACCTCT ACTTGGTGAA GAAGAGCACG TTTTGGGTAC CATTTCCTCA 2580
GCCAGCATGG GGCTAGAACA CAACCACAAT GGAGTTATTC TTGTTGAACC TGAAGTAACA 2640
AGCACACCTC TGGAGGAAGT TGTTGATGAC CTTTCTGAGA AGACTGAGGA GATAACTTCC 2700
ACTGAAGGAG ACCTGAAGGG GACAGCAGCC CCTACACTTA TATCTGAGCC TTATGAACCA 2760
TCTCCTACTC TGCACACATT AGACACAGTC TATGAAAAGC CCACCCATGA AGAGACGGCA 2820
ACAGAGGGTT GGTCTGCAGC AGATGTTGGA TCGTCACCAG AGCCCACATC CAGTGAGTAT 2880
GAGCCTCCAT TGGATGCTGT CTCCTTGGCT GAGTCTGAGC CCATGCAATA CTTTGACCCA 2940
GATTTGGAGA CTAAGTCACA ACCAGATGAG GATAAGATGA AAGAAGACAC CTTTGCACAC 3000
CTTACTCCAA CCCCCACCAT CTGGGTTAAT GACTCCAGTA CATCACAGTT ATTTGAGGAT 3060
TCTACTATAG GGGAACCAGG TGTCCCAGGC CAATCACATC TACAAGGACT GACAGACAAC 3120
ATCCACCTTG TGAAAAGTAG TCTAAGCACT CAAGACACCT TACTGATTAA AAAGGGTATG 3180
AAAGAGATGT CTCAGACACT ACAGGGAGGA AATATGCTAG AGGGAGACCC CACACACTCC 3240
AGAAGTTCTG AGAGTGAGGG CCAAGAGAGC AAATCCATCA CTTTGCCTGA CTCCACACTG 3300
GGTATAATGA GCAGTATGTC TCCAGTTAAG AAGCCTGCGG AAACCACAGT TGGTACCCTC 3360
CTAGACAAAG ACACCACAAC AGTAACAACA ACACCAAGGC AAAAAGTTGC TCCGTCATCC 3420
ACCATGAGCA CTCACCCTTC TCGAAGGAGA CCCAACGGGA GAAGGAGATT ACGCCCCAAC 3480
AAATTCCGCC ACCGGCACAA GCAAACCCCA CCCACAACTT TTGCCCCATC AGAGACTTTT 3540
TCTACTCAAC CAACTCAAGC ACCTGACATT AAGATTTCAA GTCAAGTGGA GAGTTCTCTG 3600
GTTCCTACAG CTTGGGTGGA TAACACAGTT AATACCCCCA AACAGTTGGA AATGGAGAAG 3660
AATGCAGAAC CCACATCCAA GGGAACACCA CGGAGAAAAC ACGGGAAGAG GCCAAACAAA 3720
CATCGATATA CCCCTTCTAC AGTGAGCTCA AGAGCGTCCG GATCCAAGCC CAGCCCTTCT 3780
CCAGAAAATA AACATAGAAA CATTGTTACT CCCAGTTCAG AAACTATACT TTTGCCTAGA 3840
ACTGTTTCTC TGAAAACTGA GGGCCCTTAT GATTCCTTAG ATTACATGAC AACCACCAGA 3900
AAAATATATT CATCTTACCC TAAAGTCCAA GAGACACTTC CAGTCACATA TAAACCCACA 3960
TCAGATGGAA AAGAfiATTAA GGATGATGTT GCCACAAATG TTGACAAACA TAAAAGTGAC 4020
ATTTTAGTCA CTGGTGAATC AATTACTAAT GCCATACCAA CTTCTCGCTC CTTGGTCTCC 4080
ACTATGGGAG AATTTAAGGA AGAATCCTCT CCTGTAGGCT TTCCAGGAAC TCCAACCTGG 4140
AATCCCTCAA GGACGGCCCA GCCTGGGAGG CTACAGACAG ACATACCTGT TACCACTTCT 4200
GGGGAAAATC TTACAGACCC TCCCCTTCTT AAAGAGCTTG AGGATGTGGA TTTCACTTCC 4260
GAGTTTTTGT CCTCTTTGAC AGTCTCCACA CCATTTCACC AGGAAGAAGC TGGTTCTTCC 4320
ACAACTCTCT CAAGCATAAA AGTGGAGGTG GCTTCAAGTC AGGCAGAAAC CACCACCCTT 4380
GATCAAGATC ATCTTGAAAC CACTGTGGCT ATTCTCCTTT CTGAAACTAG ACCACAGAAT 4440
CACACCCCTA CTGCTGCCCG GATGAAGGAG CCAGCATCCT CGTCCCCATC CACAATTCTC 4500
ATGTCTTTGG GACAAACCAC CACCACTAAG CCAGCACTTC CCAGTCCAAG AATATCTCAA 4560
GCATCTAGAG ATTCCAAGGA AAATGTTTTC TTGAATTATG TGGGGAATCC AGAAACAGAA 4620
GCAACCCCAG TCAACAATGA AGGAACACAG CATATGTCAG GGCCAAATGA ATTATCAACA 4680
CCCTCTTCCG ACCGGGATGC ATTTAACTTG TCTACAAAGC TGGAATTGGA AAAGCAAGTA 4740
TTTGGTAGTA GGAGTCTACC ACGTGGCCCA GATAGCCAAC GCCAGGATGG AAGAGTTCAT 4800
GCTTCTCATC AACTAACCAG AGTCCCTGCC AAACCCATCC TACCAACAGC AACAGTGAGG 4860
CTACCTGAAA TGTCCACACA AAGCGCTTCC AGATACTTTG TAACTTCCCA GTCACCTCGT 4920
CACTGGACCA ACAAACCGGA AATAACTACA TATCCTTCTG GGGCTTTGCC AGAGAACAAA 4980
CAGTTTACAA CTCCAAGATT ATCAAGTACA ACAATTCCTC TCCCATTGCA CATGTCCAAA 5040
CCCAGCATTC CTAGTAAGTT TACTGACCGA AGAACTGACC AATTCAATGG TTACTCCAAA 5100
GTGTTTGGAA ATAACAACAT CCCTGAGGCA AGAAACCCAG TTGGAAAGCC TCCCAGTCCA 5160
AGAATTCCTC ATTATTCCAA TGGAAGACTC CCTTTCTTTA CCAACAAGAC TCTTTCTTTT 5220
CCACAGTTGG GAGTCACCCG GAGACCCCAG ATACCCACTT CTCCTGCCCC AGTAATGAGA 5280
GAGAGAAAAG TTATTCCAGG TTCCTACAAC AGGATACATT CCCATAGCAC CTTCCATCTG 5340
GACTTTGGCC CTCCGGCACC TCCGTTGTTG CACACTCCGC AGACCACGGG ATCACCCTCA 5400
ACTAACTTAC AGAATATCCC TATGGTCTCT TCCACCCAGA GTTCTATCTC CTTTATAACA 5460
TCTTCTGTCC AGTCCTCAGG AAGCTTCCAC CAGAGCAGCT CAAAGTTCTT TGCAGGAGGA 5520
CCTCCTGCAT CCAAATTCTG GTCTCTTGGG GAAAAGCCCC AAATCCTCAC CAAGTCCCCA 5580
CAGACTGTGT CCGTCACCGC TGAGACAGAC ACTGTGTTCC CCTGTGAGGC AACAGGAAAA 5640
CCAAAGCCTT TCGTTACTTG GACAAAGGTT TCCACAGGAG CTCTTATGAC TCCGAATACC 5700
AGGATACAAC GGTTTGAGGT TCTCAAGAAC GGTACCTTAG TGATACGGAA GGTTCAAGTA 5760
CAAGATCGAG GCCAGTATAT GTGCACCGCC AGCAACCTGC ACGGCCTGGA CAGGATGGTG 5820
GTCTTGCTTT CGGTCACCGT GCAGCAACCT CAAATCCTAG CCTCCCACTA CCAGGACGTC 5880
ACTGTCTACC TGGGAGACAC CATTGCAATG GAGTGTCTGG CCAAAGGGAC CCCAGCCCCC 5940
CAAATTTCCT GGATCTTCCC TGACAGGAGG GTGTGGCAAA CTGTGTCCCC CGTGGAGAGC 6000
CGCATCACCC TGCACGAAAA CCGGACCCTT TCCATCAAGG AGGCGTCCTT CTCAGACAGA 6060
GGCGTCTATA AGTGCGTGGC CAGCAATGCA GCCGGGGCGG ACAGCCTGGC CATCCGCCTG 6120
CACGTGGCGG CACTGCCCCC CGTTATCCAC CAGGAGAAGC TGGAGAACAT CTCGCTGCCC 6180
CCGGGGCTCA GCATTCACAT TCACTGCACT GCCAAGGCTG CGCCCCTGCC CAGCGTGCGC 6240
TGGGTGCTCG GGGACGGTAC CCAGATCCGC CCCTCGCAGT TCCTCCACGG GAACTTGTTT 6300
GTTTTCCCCA ACGGGACGCT CTACATCCGC AACCTCGCGC CCAAGGACAG CGGGCGCTAT 6360
GAGTGCGTGG CCGCCAACCT GGTAGGCTCC GCGCGCAGGA CGGTGCAGCT GAACGTGCAG 6420
CGTGCAGCAG CCAACGCGCG CATCACGGGC ACCTCCCCGC GGAGGACGGA CGTCAGGTAC 6480
GGAGGAACCC TCAAGCTGGA CTGCAGCGCC TCGGGGGACC CCTGGCCGCG CATCCTCTGG 6540
AGGCTGCCGT CCAAGAGGAT GATCGACGCG CTCTTCAGTT TTGATAGCAG AATCAAGGTG 6600
TTTGCCAATG GGACCCTGGT GGTGAAATCA GTGACGGACA AAGATGCCGG AGATTACCTG 6660
TGCGTAGCTC GAAATAAGGT TGGTGATGAC TACGTGGTGC TCAAAGTGGA TGTGGTGATG 6720
AAACCGGCCA AGATTGAACA CAAGGAGGAG AACGACCACA AAGTCTTCTA CGGGGGTGAC 6780
CTGAAAGTGG ACTGTGTGGC CACCGGGCTT CCCAATCCCG AGATCTCCTG GAGCCTCCCA 6840
GACGGGAGTC TGGTGAACTC CTTCATGCAG TCGGATGACA GCGGTGGACG CACCAAGCGC 6900
TATGTCGTCT TCAACAATGG GACACTCTAC TTTAACGAAG TGGGGATGAG GGAGGAAGGA 6960
GACTACACCT GCTTTGCTGA AAATCAGGTC GGGAAGGACG AGATGAGAGT CAGAGTCAAG 7020
GTGGTGACAG CGCCCGCCAC CATCCGGAAC AAGACTTACT TGGCGGTTCA GGTGCCCTAT 7080
GGAGACGTGG TCACTGTAGC CTGTGAGGCC AAAGGAGAAC CCATGCCCAA GGTGACTTGG 7140
TTGTCCCCAA CCAACAAGGT GATCCCCACC TCCTCTGAGA AGTATCAGAT ATACCAAGAT 7200 GGCACTCTCC TTATTCAGAA AGCCCAGCGT TCTGACAGCG GCAACTACAC CTGCCTGGTC 7260 AGGAACAGCG CGGGAGAGGA TAGGAAGACG GTGTGGATTC ACGTCAACGT CCAGCCACCC 7320 AAGATCAACG GTAACCCCAA CCCCATCACC ACCGTGCGGG AGATAGCAGC CGGGGGCAGT 7380 CGGAAACTGA TTGACTGCAA AGCTGAAGGC ATCCCCACCC CGAGGGTGTT ATGGGCTTTT 7440 CCCGAGGGTG TGGTTCTGCC AGCTCCATAC TATGGAAACC GGATCACTGT CCATGGCAAC 7500 GGTTCCCTGG ACATCAGGAG TTTGAGGAAG AGCGACTCCG TCCAGCTGGT ATGCATGGCA 7560
CGCAACGAGG GAGGGGAGGC GAGGTTGATC GTGCAGCTCA CTGTCCTGGA GCCCATGGAG 7620
AAACCCATCT TCCACGACCC GATCAGCGAG AAGATCACGG CCATGGCGGG CCACACCATC 7680
AGCCTCAACT GCTCTGCCGC GGGGACCCCG ACACCCAGCC TGGTGTGGGT CCTTCCCAAT 7740
GGCACCGATC TGCAGAGTGG ACAGCAGCTG CAGCGCTTCT ACCACAAGGC TGACGGCATG 7800
CTACACATTA GCGGTCTCTC CTCGGTGGAC GCTGGGGCCT ACCGCTGCGT GGCCCGCAAT 7860
GCCGCTGGCC ACACGGAGAG GCTGGTCTCC CTGAAGGTGG GACTGAAGCC AGAAGCAAAC 7920
AAGCAGTATC ATAACCTGGT CAGCATCATC AATGGTGAGA CCCTGAAGCT CCCCTGCACC 7980
CCTCCCGGGG CTGGGCAGGG ACGTTTCTCC TGGACGCTCC CCAATGGCAT GCATCTGGAG 8040
GGCCCCCAAA CCCTGGGACG CGTTTCTCTT CTGGACAATG GCACCCTCAC GGTTCGTGAG 8100
GCCTCGGTGT TTGACAGGGG TACCTATGTA TGCAGGATGG AGACGGAGTA CGGCCCTTCG 8160
GTCACCAGCA TCCCCGTGAT TGTGATCGCC TATCCTCCCC GGATCACCAG CGAGCCCACC 8220
CCGGTCATCT ACACCCGGCC CGGGAACACC GTGAAACTGA ACTGCATGGC TATGGGGATT 8280
CCCAAAGCTG ACATCACGTG GGAGTTACCG GATAAGTCGC ATCTGAAGGC AGGGGTTCAG 8340
GCTCGTCTGT ATGGAAACAG ATTTCTTCAC CCCCAGGGAT CACTGACCAT CCAGCATGCC 8400
ACACAGAGAG ATGCCGGCTT CTACAAGTGC ATGGCAAAAA ACATTCTCGG CAGTGACTCC 8460
AAAACAACTT ACATCCACGT CTTCTGAAAT GTGGATTCCA GAATGATTGC TTAGGAACTG 8520
ACAACAAAGC GGGGTTTGTA AGGGAAGCCA GGTTGGGGAA TAGGAGCTCT TAAATAATGT 8580
GTCACAGTGC ATGGTGGCCT CTGGTGGGTT TCAAGTTGAG GTTGATCTTG ATCTACAATT 8640
GTTGGGAAAA GGAAGCAATG CAGACACGAG AAGGAGGGCT CAGCCTTGCT GAGACACTTT 8700
CTTTTGTGTT TACATCATGC CAGGGGCTTC ATTCAGGGTG TCTGTGCTCT GACTGCAATT 8760
TTTCTTCTTT TGCAAATGCC ACTCGACTGC CTTCATAAGC GTCCATAGGA TATCTGAGGA 8820
ACATTCATCA AAAATAAGCC ATAGACATGA ACAACACCTC ACTACCCCAT TGAAGACGCA 8880
TCACCTAGTT AACCTGCTGC AGTTTTTACA TGATAGACTT TGTTCCAGAT TGACAAGTCA 8940
TCTTTCAGTT ATTTCCTCTG TCACTTCAAA ACTCCAGCTT GCCCAATAAG GATTTAGAAC 9000
CAGAGTGACT GATATATATA TATATATTTT AATTCAGAGT TACATACATA CAGCTACCAT 9060
TTTATATGAA AAAAGAAAAA CATTTCTTCC TGGAACTCAC TTTTTATATA ATGTTTTATA 9120
TATATATTTT TTCCTTTCAA ATCAGACGAT GAGACTAGAA GGAGAAATAC TTTCTGTCTT 9180
ATTAAAATTA ATAAATTATT GGTCTTTACA AGACTTGGAT ACATTACAGC AGACATGGAA 9240
ATATAATTTT AAAAAATTTC TCTCCAACCT CCTTCAAATT CAGTGACCAC TGTTATATTA 9300
CCTTCTCCAG GAACCCTCCA GTGGGGAAGG CTGCGATATT AGATTTCCTT GTATGCAAAG 9360
TTTTTGTTGA AAGCTGTGCT CAGAGGAGGT GAGAGGAGAG GAAGGAGAAA ACTGCATCAT 9420
AACTTTACAG AATTGAATCT AGAGTCTTCC CCGAAAAGCC CAGAAACTTC TCTGCAGTAT 9480
CTGGCTTGTC CATCTGGTCT AAGGTGGCTG CTTCTTCCCC AGCCATGAGT CAGTTTGTGC 9540
CCATGAATAA TACACGACCT GTTATTTCCA TGACTGCTTT ACTGTATTTT TAAGGTCAAT 9600
ATACTGTACA TTTGATAATA AAATAATATT CTCCCAAAAA AAAAA
Seq ID NO: 58 Protein sequence Protein Accession #: NP 056234.1
11 21 31 41 51
I I I I I
MPKRAHWGAL SWLILLWGH PRVALACPHP CACYVPSEVH CTFRSLASVP AGIARHVERI 60
NLGFNSIQAL SETSFAGLTK LELLMIHGNE IPSIPDGALR DLSSLQVFKF SYNKLRVITG 120
QTLQGLSNLM RLHIDHNKIE FIHPQAFNGL TSLRLLHLEG NLLHQLHPST FSTFTFLDYF 180
RLSTIRHLYL AENMVRTLPA SMLRNMPLLE NLYLQGNPWT CDCEMRWFLE WDAKSRGILK 240
CKKDKAYEGG QLCAMCFSPK KLYKHEIHKL KDMTCLKPSI ESPLRQNRSR SIEEEQEQEE 300
DGGSQLILEK FQLPQWSISL NMTDEHGNMV NLVCDIKKPM DVYKIHLNQT DPPDIDINAT 360
VALDFECPMT RENYEKLWKL IAYYSEVPVK LHRELMLSKD PRVSYQYRQD ADEEALYYTG 420
VRAQILAEPE WVMQPSIDIQ LNRRQSTAKK VLLSYYTQYS QTISTKDTRQ ARGRSWVMIE 480
PSGAVQRDQT VLEGGPCQLS CNVKASESPS IFWVLPDGSI LKAPMDDPDS KFSILSSGWL 540
RIKSMEPSDS GLYQCIAQVR DEMDRMVYRV LVQSPSTQPA EKDTVTIGKN PGESVTLPCN 600
ALAIPEAHLS WILPNRRIIN DLANTSHVYM LPNGTLSIPK VQVSDSGYYR CVAVNQQGAD 660
HFTVGITVTK KGSGLPSKRG RRPGAKALSR VREDIVEDEG GSGMGDEENT SRRLLHPKDQ 720
EVFLKTKDDA INGDKKAKKG RRKLKLWKHS EKEPETNVAE GRRVFESRRR INMANKQINP 780
ERWADILAKV RGKNLPKGTE VPPLIKTTSP PSLSLEVTPP FPAVSPPSAS PVQTVTSAEE 840
SSADVPLLGE EEHVLGTISS ASMGLEHNHN GVILVEPEVT STPLEEWDD LSEKTEEITS 900
TEGDLKGTAA PTLISEPYEP SPTLHTLDTV YEKPTHEETA TEGWSAADVG SSPEPTSSEY 960
EPPLDAVSLA ESEPMQYFDP DLETKSQPDE DKMKEDTFAH LTPTPTIWVN DSSTSQLFED 1020
STIGEPGVPG QSHLQGLTDN IHLVKSSLST QDTLLIKKGM KEMSQTLQGG NMLEGDPTHS 1080
RSSESEGQES KSITLPDSTL GIMSSMSPVK KPAETTVGTL LDKDTTTVTT TPRQKVAPSS 1140
TMSTHPSRRR PNGRRRLRPN KFRHRHKQTP PTTFAPSETF STQPTQAPDI KISSQVESSL 1200
VPTAWVDNTV NTPKQLEMEK NAEPTSKGTP RRKHGKRPNK HRYTPSTVSS RASGSKPSPS 1260
PENKHRNIVT PSSETILLPR TVSLKTEGPY DSLDYMTTTR KIYSSYPKVQ ETLPVTYKPT 1320
SDGKEIKDDV ATNVDKHKSD ILVTGESITN AIPTSRSLVS TMGEFKEESS PVGFPGTPTW 1380
NPSRTAQPGR LQTDIPVTTS GENLTDPPLL KELEDVDFTS EFLSSLTVST PFHQEEAGSS 1440
TTLSSIKVEV ASSQAETTTL DQDHLETTVA ILLSETRPQN HTPTAARMKE PASSSPSTIL 1500
MSLGQTTTTK PALPSPRISQ ASRDSKENVF LNYVGNPETE ATPVNNEGTQ HMSGPNELST 1560
PSSDRDAFNL STKLELEKQV FGSRSLPRGP DSQRQDGRVH ASHQLTRVPA KPILPTATVR 1620
LPEMSTQSAS RYFVTSQSPR HWTNKPEITT YPSGALPENK QFTTPRLSST TIPLPLHMSK 1680
PSIPSKFTDR RTDQFNGYSK VFGNNNIPEA RNPVGKPPSP RIPHYSNGRL PFFTNKTLSF 1740
PQLGVTRRPQ IPTSPAPVMR ERKVIPGSYN RIHSHSTFHL DFGPPAPPLL HTPQTTGSPS 1800
TNLQNIPMVS STQSSISFIT SSVQSSGSFH QSSSKFFAGG PPASKFWSLG EKPQILTKSP 1860
QTVSVTAETD TVFPCEATGK PKPFVTWTKV STGALMTPNT RIQRFEVLKN GTLVIRKVQV 1920
QDRGQYMCTA SNLHGLDRMV VLLSVTVQQP QILASHYQDV TVYLGDTIAM ECLAKGTPAP 1980
QISWIFPDRR VWQTVSPVES RITLHENRTL SIKEASFSDR GVYKCVASNA AGADSLAIRL 2040
HVAALPPVIH QEKLENISLP PGLSIHIHCT AKAAPLPSVR WVLGDGTQIR PSQFLHGNLF 2100
VFPNGTLYIR NLAPKDSGRY ECVAANLVGS ARRTVQLNVQ RAAANARITG TSPRRTDVRY 2160
GGTLKLDCSA SGDPWPRILW RLPSKRMIDA LFSFDSRIKV FANGTLWKS VTDKDAGDYL 2220
CVARNKVGDD YWLKVDWM KPAKIEHKEE NDHKVFYGGD LKVDCVATGL PNPEISWSLP 2280
DGSLVNSFMQ SDDSGGRTKR YWFNNGTLY FNEVGMREEG DYTCFAENQV GKDEMRVRVK 2340
WTAPATIRN KTYLAVQVPY GDWTVACEA KGEPMPKVTW LSPTNKVIPT SSEKYQIYQD 2400
GTLLIQKAQR SDSGNYTCLV RNSAGEDRKT VWIHVNVQPP KINGNPNPIT TVREIAAGGS 2460
RKLIDCKAEG IPTPRVLWAF PEGWLPAPY YGNRITVHGN GSLDIRSLRK SDSVQLVCMA 2520 RNEGGEARLI VQLTVLEPME KPIFHDPISE KITAMAGHTI SLNCSAAGTP TPSLVWVLPN 2580
GTDLQSGQQL QRFYHKADGM LHISGLSSVD AGAYRCVARN AAGHTERLVS LKVGLKPEAN 2640
KQYHNLVSII NGETLKLPCT PPGAGQGRFS WTLPNGMHLE GPQTLGRVSL LDNGTLTVRE 2700
ASVFDRGTYV CRMETEYGPS VTSIPVIVIA YPPRITSEPT PVIYTRPGNT VKLNCMAMGI 2760
PKADITWELP DKSHLKAGVQ ARLYGNRFLH PQGSLTIQHA TQRDAGFYKC MAKNILGSDS 2820 KTTYIHVF
Seq ID NO: 59 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..5001
11 21 31 41 51
ATGCCAGGCA CAAAACTAAC CCGAACAGGC GCCCCAGCAG ACTACAGAGT GATATTGAAG 60
ACCTCTCAAG AGGACGAATT GGATGTACCT GACGACATCA GCGTCCGGGT TATGTCATCT 120
CAGTCTGTGC TTGTGTCCTG GGTGGATCCT GTTCTGGAAA AACAGAAGAA AGTTGTTGCA 180
TCAAGACAGT ACACCGTGCG CTATCGAGAG AAGGGGGAAT TGGCCAGGTG GGATTATAAG 240
CAGATCGCTA ACAGGCGTGT GCTGATTGAG AACCTGATTC CAGACACTGT GTATGAATTT 300
GCAGTCCGTA TTTCACAGGG TGAAAGAGAT GGCAAATGGA GTACGTCAGT CTTCCAAAGA 360
ACACCAGAAT CTGCCCCTAC CACAGCTCCT GAAAACTTGA ACGTCTGGCC AGTCAATGGC 420
AAACCTACAG TTGTCGCTGC ATCTTGGGAT GCGCTACCAG AGACTGAGGG GAAAGTGAAA 480
GTCTGTCTGC TGGACACAGG ACTGTTTTCA GTTTCCTCCT TCCAACCATC TGCCAAATCA 540
TTTCAGAATA CATTCTTTCA TACGCCCCGG CTCTCAAACC ATTTGGAGCA AAGTCCCTCA 600
CCTATCCTGG AGACACTACT TCTGCCCTGG TGGATGGTCT GCAGCCTGGG GAACGCTATC 660
TTTTCAAAAT CCGGGCCACA AACAGGAGAG GCCTGGGACC TCACTCCAAA GCCTTCATTG 720
TCGCTATGCC AACAAGAATG CAGCTGTACC CAGAAGGATT TCAGTTGTCT AGCTTACCTG 780
ATCGATATCC AAACCAAACA AGTTAATAAA GATCCACAAC TGGAAGGGAG TGTTTTTGGA 840
CCATGTTTTC TTTTCTACTT CCTCACATTT ATGCTGGATA TTGGCGGCTT TTCCTTCATT 900
ATGTGCTATG AAGACCCANN TGTTTCTTCT TTGACAGGCA ATTCTTTAAA ATCTGTTGCA 960
GCCAGTAAGG CGGATGTTCA GCAGAACACG GAGGACAATG GGAAACCCGA AAAACCTGAG 1020
CCTTCCTCAC CTTCTCCCAG AGCTCCAGCT TCCTCCCAAC ACCCCTCTGT GCCTGCTTCT 1080
CCCCAAGGGA GAAATGCCAA GGACCTTCTT CTTGACTTGA AGAACAAAAT ATTGGCTAAT 1140
GGTGGGGCGC CCCGAAAACC CCAGCTTCGC GCCAAGAAGG CAGAGGAGCT GGATCTTCAG 1200
TCGACAGAAA TCACTGGGGA GGAGGAGCTG GGTTCCCGGG AGGACTCGCC CATGTCACCC 1260
TCAGACACCC AAGACCAGAA ACGGACCCTG AGGCCGCCAA GTAGACACGG CCACTCGGTG 1320
GTTGCTCCCG GCAGGACTGC AGTGAGGGCC CGGATGCCAG CGCTGCCCCG AAGGGAAGGC 1380
GTAGATAAGC CTGGCTTTTC CCTGGCCACG CAGCCCCGCC CAGGGGCGCC CCCCTCGGCT 1440
TCGGCCTCTC CTGCCCACCA CGCGTCCACC CAGGGCACCT CTCATCGTCC TTCCCTGCCT 1500
GCCAGCTTGA ATGACAACGA CTTGGTGGAC TCAGACGAAG ATGAGCGCGC TGTGGGCTCC 1560
CTCCACCCCA AGGGCGCCTT CGCCCAGCCC CGGCCAGCCC TGTCCCCCAG CCGCCAGTCC 1620
CCGTCCAGCG TTCTCCGCGA CAGAAGCTCT GTGCACCCCG GCGCAAAGCC AGCCTCGCCG 1680
GCGCGGAGGA CCCCCCATTC AGGGGCCGCA GAGGAAGATT CCAGTGCCTC AGCCCCACCC 1740
TCAAGACTTT CTCCACCCCA TGGGGGATCA TCTCGGCTGC TGCCCACCCA GCCACACCTG 1800
AGCTCTCCAC TTTCCAAGGG CGGGAAGGAT GGTGAGGACG CCCCAGCCAC CAACTCCAAT 1860
GCGCCATCAC GGTCCACCAT GTCCTCCTCC GTCTCTTCTC ATCTCTCGTC CAGGACGCAG 1920
GTCTCTGAGG GAGCGGAGGC TTCTGATGGT GAAAGCCACG GTGACGGCGA TAGGGAAGAC 1980
GGCGGAAGGC AGGCGGAGGC CACGGCCCAG ACGCTGCGGG CCCGGCCTGC CTCTGGACAC 2040
TTCCATTTGC TCAGACACAA ACCCTTTGCT GCCAACGGGA GGTCTCCAAG CAGGTTCAGC 2100
ATTGGGCGGG GACCTCGGCT GCAGCCCTCC AGCTCCCCAC AGTCGACTGT GCCCTCCCGA 2160
GCCCACCCCA GGGTTCCCTC TCACTCTGAT TCCCACCCTA AGCTTAGCTC AGGTATCCAT 2220
GGAGACGAGG AGGATGAGAA GCCGCTTCCT GCCACCGTTG TCAATGACCA CGTGCCTTCC 2280
TCCTCCAGGC AGCCCATCTC CCGGGGCTGG GAGGACTTAA GGAGAAGCCC GCAGAGAGGG 2340
GCCAGCCTGC ATCGGAAGGA ACCCATCCCA GAGAACCCCA AATCCACAGG GGCAGATACA 2400
CATCCTCAGG GCAAGTACTC CTCCCTGGCC TCCAAGGCTC AGGATGTTCA ACAGAGCACA 2460
GACGCGGACA CGGAGGGTCA TTCTCCCAAA GCACAGCCAG GGTCCACAGA CCGCCACGCG 2520
TCCCCTGCTC GTCCTCCCGC AGCACGGTCA CAGCAGCATC CCAGTGTTCC CAGAAGGATG 2580
ACACCCGGCC GGGCCCCAGA ACAGCAGCCC CCTCCTCCCG TCGCCACGTC CCAGCACCAC 2640
CCGGGACCCC AGAGCAGAGA CGCGGGTCGG TCACCTTCCC AGCCCAGGCT CTCACTGACC 2700
CAGGCCGGGC GGCCCCGCCC CACGTCGCAG GGCCGCTCCC ACTCCTCCTC GGACCCTTAC 2760
ACGGCGAGCT CCAGAGGGAT GCTCCCCACG GCCCTCCAGA ACCAGGACGA GGATβCCCAG 2820
GGCAGCTACG ACGACGACAG CACAGAAGTC GAGGCCCAGG ATGTGCGGGC CCCCGCGCAC 2880
GCCGCGCGCG CCAAGGAGGC AGCTGCGTCC CTTCCCAAGC ACCAGCAGGT GGAGTCTCCC 2940
ACAGGCGCAG GGGCAGGTGG CGACCACAGG TCCCAGCGCG GACATGCGGC CTCCCCCGCC 3000
AGGCCCAGCC GACCCGGCGG CCCCCAGTCC CGCGCCCGGG TCCCCAGCAG GGCAGCGCCG 3060
GGGAAGTCGG AGCCTCCTTC CAAGCGGCCC CTGTCCTCCA AGTCCCAGCA GTCGGTCTCA 3120
GCCGAGGACG AGGAGGAGGA GGACGCGGGG TTTTTTAAAG GCGGGAAAGA AGACCTTCTG 3180
TCTTCCTCTG TGCCAAAGTG GCCCTCTTCC TCCACTCCCA GGGGCGGCAA AGACGCCGAT 3240
GGGAGCCTCG CCAAGGAAGA GAGGGAGCCT GCCATCGCGC TTGCCCCTCG CGGAGGGAGC 3300
CTGGCTCCTG TGAAGCGACC TCTCCCCCCA CCTCCAGGCA GCTCCCCCAG GGCCTCCCAC 3360
GTCCCTTCCC GACCGCCGCC TCGCAGCGCT GCCACCGTGA GCCCCGTCGC GGGCACCCAC 3420
CCCTGGCCGC GGTACACCAC GCGCGCCCCV CCTGGCCACT TCTCCACCAC CCCGATGCTG 3480
TCCTTGCGCC AGAGGATGAT GCATGCCAGA TTCCGTAACC CTCTCTCCCG ACAGCCTGCC 3540
AGACCCTCTT ACAGACAAGG TTATAATGGC AGACCAAATG TAGAAGGGAA AGTCCTTCCT 3600
GGTAGTAATG GAAAACCGAA TGGACAGAGA ATTATCAATG GCCCTCAAGG AACAAAGTGG 3660
GTTGTGGACC TTGATCGTGG GTTAGTATTG AATGCAGAAG GAAGGTACCT CCAAGATTCA 3720
CATGGAAATC CTCTTCGGAT TAAACTAGGA GGAGATGGTC GAACCATTGT AGATCTGGAA 3780
GGGACCCCCG TGGTGAGTCC TGACGGCCTC CCACTCTTTG GGCAGGGGCG ACATGGCACA 3840
CCTCTGGCCA ATGCCCAAGA TAAGCCAATT TTGAGTCTTG GAGGAAAGCC GCTGGTGGGC 3900
TTGGAGGTCA TCAAAAAAAC CACCCATCCC CCTACCACTA CCATGCAGCC CACCACTACT 3960
ACGACGCCCC TGCCTACCAC TACAACCCCG AGGCCCACCA CTGCCACCAC CATGCAGCCC 4020
ACCACTACTA CGACGCCCCT GCCTACCACT ACACCGAGGC CCACCACTGC CACCACCCGC 4080
CGCACGACCA CCAGGCGTCC AACAACCACA GTCCGAACCA CTACGCGGAC AACCACCACC 4140
ACCACCCCCA AACCCACCAC TCCCATCCCC ACCTGTCCCC CTGGGACCTT GGAACGGCAC 4200
GACGATGATG GCAACCTGAT AATGAGCTCC AATGGGATCC CAGAGTGCTA CGCTGAAGAA 4260 GATGAGTTCT CAGGCTTGGA GACTGACACT GCAGTACCTA GGGAAGAGGC CTACGTTATA 4320 TATGATGAAG ATTATGAATT TGAGACGTCA AGGCCACCAA CCACCACTGA GCCTTCGACC 4380 ACTGCTACCA CACCGAGGGT GATCCCAGAG GAAGGCGCCA TCAGTTCCTT TCCTGAAGAA 4440 GAATTTGATC TGGCTGGAAG GAAACGATTT GTTGCTCCTT ACGTGACGTA CCTAAATAAA 4500 GACCCATCAG CCCCGTGCTC TCTGACTGAT GCACTGGATC ACTTCCAAGT GGACAGCCTG 4560 GATGAAATCA TCCCCAATGA CCTGAAGAAG AGTGATCTGC CTCCCCAGCA TGCTCCCCGC 4620 AACATCACCG TGGTGGCCGT GGAAGGTTGC CACTCATTTG TCATTGTGGA TTGGGACAAA 4680 GCCACCCCAG GAGATTTGGT CACAGGTTAT TTGGTTTACA GTGCATCCTA TGAAGATTTC 4740 ATCAGGAACA AGTTTTCCAC TCAAGCTTCA TCAGTAACTC ACTTGCCCAT TGAGAACCTA 4800 AAGCCCAACA CGAGGTATTA TTTTAAAGTG CAAGCACAAA ATCCTCATGG CTACGGACCT 4860 ATCAGCCCTT CGGTCTCATT TGTCACCGAA TCAGATAATC CTCTGCTTGT TGTGAGGCCC 4920 CCAGGCGGTG AGCTATCTGG ATCCCATTCG CTTTCAAACA TGATCCCAGC TACACGGACT 4980 GCCATGGACG GCAATATGTG AAGCGCACGT GGTATCGAAA GTTCGTGGGA GTTGTTCTTT 5040 GTAATTCACT GAGGTATAAA ATCTACCTCA GTGACAACCT GAAAGATACA TTCTACAGCA 5100 TTGGAGACAG CTGGGGAAGA GGTGAAGACC ATTGCCAATT TGTGGATTCA CACCTTGATG 5160 GAAGAACAGG GCCTCAGTCC TATGTAGAAG CCCTCCCTAC TATTCAAGGC TACTATCGCC 5220 AGTATCGTCA GGAGCCTGTC AGGTTTGGGA ACATCGGCTT CGGAACCCCC TACTACTATG 5280 TGGGCTGGTA CGAGTGTGGG GTCTCCATCC CTGGAAAGTG GTAATCACAG GACCGTCATG 5340 CTGCAAGCTT GCCCTGCCCA GCCCCACCAA CTAAGTCGCA CTAGGGGCTG TGAGCAAAGA 5400 CAGCCAGCAT GCTCAGCCCC GCTGCCCTAG GTGCCAGGAA GGTCACAGAT GGACACTGGC 5460 CATTCTGGTC ATCTCAGTCT GGAACTCAGT CCCACTTCTT GGCCTGGACA ATGAACAGGA 5520 TTCAGTTTTG CTGTTAACTT TGCTTCTCTA CTTTTTTTTG TTTGTTTGTA ATAGCACATC 5580 CCAGAGACAT CAGAAACCAG CAACTGATTC AGTGTGATTT CCCAGACTTT TTAGGCATGA 5640 AATTCGGACA CTTCAGTATT TCCAGGAATA GCATATGCAC GCTGTTCTTG CTTCATGGAA 5700 TGCTACATGC TTTCTGTTTT TCTCATTTTG GATTTCTCCA AAACTAACTG AATTTAAGCT 5760 TCAGGTCCCT TTGTATGCAG TAGAAAGGAA TTATTAAAAA CACCACCAAA GAAAATAAAT 5820 ATATCCTACT TGAAATTTAC TCTATGGACT TACCCACTGC TAGAATAAAT GTATCAAATC 5880 TTATTTGTAA ATTCTCAATT TTGATATATA TATGTATATA TGCATATACA TATCCACACT 5940 TGTCTGCAAG AATATTGATT AAAATTGCTA AATTTGTACT TGTTCACCAA AAAAAAAAAA 6000 AAAAAAA
Seq ID NO: 60 Protein sequence Protein Accession tt: Eos sequence
11 21 31 41 51
I I I I I
MPGTKLTRTG APADYRVILK TSQEDELDVP DDISVRVMSS QSVLVSWVDP VLEKQKKWA 60 SRQYTVRYRE KGELARWDYK QIANRRVLIE NLIPDTVYEF AVRISQGERD GKWSTSVFQR 120 TPESAPTTAP ENLNVWPVNG KPTWAASWD ALPETEGKVK VCLLDTGLFS VSSFQPSAKS 180 FQNTFFHTPR LSNHLEQSPS PILETLLLPW WMVCSLGNAI FSKSGPQTGE AWDLTPKPSL 240 SLCQQECSCT QKDFSCLAYL IDIQTKQVNK DPQLEGSVFG PCFLFYFLTF MLDIGGFSFI 300 MCYEDPVSSL TGNSLKSVAA SKADVQQNTE DNGKPEKPEP SSPSPRAPAS SQHPSVPASP 360 QGRNAKDLLL DLKNKILANG GAPRKPQLRA KKAEELDLQS TEITGEEELG SREDSPMSPS 420 DTQDQKRTLR PPSRHGHSW APGRTAVRAR MPALPRREGV DKPGFSLATQ PRPGAPPSAS 480 ASPAHHASTQ GTSHRPSLPA SLNDNDLVDS DEDERAVGSL HPKGAFAQPR PALSPSRQSP 540 SSVLRDRSSV HPGAKPASPA RRTPHSGAAE EDSSASAPPS RLSPPHGGSS RLLPTQPHLS 600 SPLSKGGKDG EDAPATNSNA PSRSTMSSSV SSHLSSRTQV SEGAEASDGE SHGDGDREDG 660 GRQAEATAQT LRARPASGHF HLLRHKPFAA NGRSPSRFSI GRGPRLQPSS SPQSTVPSRA 720 HPRVPSHSDS HPKLSSGIHG DEEDEKPLPA TWNDHVPSS SRQPISRGWE DLRRSPQRGA 780 SLHRKEPIPE NPKSTGADTH PQGKYSSLAS KAQDVQQSTD ADTEGHSPKA QPGSTDRHAS 840 PARPPAARSQ QHPSVPRRMT PGRAPEQQPP PPVATSQHHP GPQSRDAGRS PSQPRLSLTQ 900 AGRPRPTSQG RSHSSΞDPYT ASSRGMLPTA LQNQDEDAQG SYDDDSTEVE AQDVRAPAHA 960 ARAKEAAASL PKHQQVESPT GAGAGGDHRS QRGHAASPAR PSRPGGPQSR ARVPSRAAPG 1020 KSEPPSKRPL SSKSQQSVSA EDEEEEDAGF FKGGKEDLLS SSVPKWPSSS TPRGGKDADG 1080 SLAKEEREPA IALAPRGGSL APVKRPLPPP PGSSPRASHV PSRPPPRSAA TVSPVAGTHP 1140 WPRYTTRAPP GHFSTTPMLS LRQRMMHARF RNPLSRQPAR PSYRQGYNGR PNVEGKVLPG 1200 SNGKPNGQRI INGPQGTKWV VDLDRGLVLN AEGRYLQDSH GNPLRIKLGG DGRTIVDLEG 1260 TPWSPDGLP LFGQGRHGTP LANAQDKPIL SLGGKPLVGL EVIKKTTHPP TTTMQPTTTT 1320 TPLPTTTTPR PTTATTMQPT TTTTPLPTTT PRPTTATTRR TTTRRPTTTV RTTTRTTTTT 1380 TPKPTTPIPT CPPGTLERHD DDGNLIMSSN GIPECYAEED EFSGLETDTA VPTEEAYVIY 1440 DEDYEFETSR PPTTTEPSTT ATTPRVIPEE GAISSFPEEE FDLAGRKRFV APYVTYLNKD 1500 PSAPCSLTDA LDHFQVDSLD EIIPNDLKKS DLPPQHAPRN ITWAVEGCH SFVIVDWDKA 1560 TPGDLVTGYL VYSASYEDFI RNKFSTQASS VTHLPIENLK PNTRYYFKVQ AQNPHGYGPI 1620 SPSVSFVTES DNPLLWRPP GGELSGSHSL SNMIPATRTA MDGNM
Seq ID NO: 61 DNA sequence
Nucleic Acid Accession ft: NM_022743
Coding sequence: 128..1237
11 21 31 41 51
I I I I I
GTGGATTTTA GAGATACCTC CCCTCCTTCT GCTCAGCTGC CTTGCAGTAA TTAAACTCTT 60 TCTCTGCTGC AACACCCCTA CTGTTCTCCG TGTATTGGCT TTTCTGGGCA GCAGGAAGGA 120 AAAGCTGATG CGATGCTCTC AGTGCCGCGT CGCCAAATAC TGTAGTGCTA AGTGTCAGAA 180 AAAAGCTTGG CCAGACCACA AGCGGGAATG CAAATGCCTT AAAAGCTGCA AACCCAGATA 240 TCCTCCAGAC TCCGTTCGAC TTCTTGGCAG AGTTGTCTTC AAACTTATGG ATGGAGCACC 300 TTCAGAATCA GAGAAGCTTT ACTCATTTTA TGATCTGGAG TCAAATATTA ACAAACTGAC 360 TGAAGATAAG AAAGAGGGCC TCAGGCAACT CGTAATGACA TTTCAACATT TCATGAGAGA 420 AGAAATACAG GATGCCTCTC AGCTGCCACC TGCCTTTGAC CTTTTTGAAG CCTTTGCAAA 480 AGTGATCTGC AACTCTTTCA CCATCTGTAA TGCGGAGATG CAGGAAGTTG GTGTTGGCCT 540 ATATCCCAGT ATCTCTTTGC TCAATCACAG CTGTGACCCC AACTGTTCGA TTGTGTTCAA 600 TGGGCCCCAC CTCTTACTGC GAGCAGTCCG AGACATCGAG GTGGGAGAGG AGCTCACCAT 660 CTGCTACCTG GATATGCTGA TGACCAGTGA GGAGCGCCGG AAGCAGCTGA GGGACCAGTA 720 CTGCTTTGAA TGTGACTGTT TCCGTTGCCA AACCCAGGAC AAGGATGCTG ATATGCTAAC 780 TGGTGATGAG CAAGTATGGA AGGAAGTTCA AGAATCCCTG AAAAAAATTG AAGAACTGAA 840 GGCACACTGG AAGTGGGAGC AGGTTCTGGC CATGTGCCAG GCGATCATAA GCAGCAATTC 900 TGAACGGCTT CCCGATATCA ACATCTACCA GCTGAAGGTG CTCGACTGCG CCATGGATGC 960 CTGCATCAAC CTCGGCCTGT TGGAGGAAGC CTTGTTCTAT GGTACTCGGA CCATGGAGCC 1020 ATACAGGATT TTTTTCCCAG GAAGCCATCC CGTCAGAGGG GTTCAAGTGA TGAAAGTTGG 1080 CAAACTGCAG CTACATCAAG GCATGTTTCC CCAAGCAATG AAGAATCTGA GACTGGCTTT 1140 TGATATTATG AGAGTGACAC ATGGCAGAGA ACACAGCCTG ATTGAAGATT TGATTCTACT 1200 TTTAGAAGAA TGCGACGCCA ACATCAGAGC ATCCTAAGGG AACGCAGTCA GAGGGAAATA 1260 CGGCGTGTGT CTTTGTTGAA TGCCTTATTG AGGTCACACA CTCTATGCTT TGTTAGCTGT 1320 GTGAACCTCT CTTATTGGAA ATTCTGTTCC GTGTTTGTGT AGGTAAATAA AGGCAGACAT 1380 GGTTTGCAAA CCACAAGAAT CATTAGTTGT AGAGAAGCAC GATTATAATA AATTCAAAAC 1440 ATTTGGTTGA GGATGCCAAA AAAAAAAAAA AAAAAAA
Seq ID NO: 62 Protein sequence Protein Accession #: NP 073580
11 21 31 41 51
I I I I i
MRCSQCRVAK YCSAKCQKKA WPDHKRECKC LKSCKPRYPP DSVRLLGRW FKLMDGAPSE 60 SEKLYSFYDL ESNINKLTED KKEGLRQLVM TFQHFMREEI QDASQLPPAF DLFEAFAKVI 120 CNSFTICNAE MQEVGVGLYP SISLLNHSCD PNCSIVFNGP HLLLRAVRDI EVGEELTICY 180 LDMLMTSEER RKQLRDQYCF ECDCFRCQTQ DKDADMLTGD EQVWKEVQES LKKIEELKAH 240 WKWEQVLAMC QAIISSNSER LPDINIYQLK VLDCAMDACI NLGLLEEALF YGTRTMEPYR 300 IFFPGSHPVR GVQVMKVGKL QLHQGMFPQA MKNLRLAFDI MRVTHGREHS LIEDLILLLE 360 ECDANIRAS
Seq ID NO: 63 DNA sequence
Nucleic Acid Accession It: NM_003014.2
Coding sequence: 238.-648
11 21 31 41
GGCGGGTTCG CGCCCCGAAG GCTGAGAGCT GGCGCTGCTC GTGCCCTGTG TGCCAGACGG 60 CGGAGCTCCG CGGCCGGACC CCGCGGCCCC GCTTTGCTGC CGACTGGAGT TTGGGGGAAG 120 AAACTCTCCT GCGCCCCAGA AGATTTCTTC CTCGGCGAAG GGACAGCGAA . AGATGAGGGT 180 GGCAGGAAGA GAAGGCGCTT TCTGTCTGCC GGGGTCGCAG CGCGAGAGGG CAGTGCCATG 240 TTCCTCTCCA TCCTAGTGGC GCTGTGCCTG TGGCTGCACC TGGCGCTGGG CGTGCGCGGC 300 GCGCCCTGCG AGGCGGTGCG CATCCCTATG TGCCGGCACA TGCCCTGGAA CATCACGCGG 360 ATGCCCAACC ACCTGCACCA CAGCACGCAG GAGAACGCCA TCCTGGCCAT CGAGCAGTAC 420 GAGGAGCTGG TGGACGTGAA CTGCAGCGCC GTGCTGCGCT TCTTCTTCTG TGCCATGTAC 480 GCGCCCATTT GCACCCTGGA GTTCCTGCAC GACCCTATCA AGCCGTGCAA GTCGGTGTGC 540 CAACGCGCGC GCGACGACTG CGAGCCCCTC ATGAAGATGT ACAACCACAG CTGGCCCGAA 600 AGCCTGGCCT GCGACGAGCT GCCTGTCTAT GACCGTGGCG TGTGCATTTC GCCTGAAGCC 660 ATCGTCACGG ACCTCCCGGA GGATGTTAAG TGGATAGACA TCACACCAGA CATGATGGTA 720 CAGGAAAGGC CTCTTGATGT TGACTGTAAA CGCCTAAGCC CCGATCGGTG CAAGTGTAAA 780 AAGGTGAAGC CAACTTTGGC AACGTATCTC AGCAAAAACT ACAGCTATGT TATTCATGCC 840 AAAATAAAAG CTGTGCAGAG GAGTGGCTGC AATGAGGTCA CAACGGTGGT GGATGTAAAA 900 GAGATCTTCA AGTCCTCATC ACCCATCCCT CGAACTCAAG TCCCGCTCAT TACAAATTCT 960 TCTTGCCAGT GTCCACACAT CCTGCCCCAT CAAGATGTTC TCATCATGTG TTACGAGTGG 1020 CGTTCAAGGA TGATGCTTCT TGAAAATTGC TTAGTTGAAA AATGGAGAGA TCAGCTTAGT 1080 AAAAGATCCA TACAGTGGGA AGAGAGGCTG CAGGAACAGC GGAGAACAGT TCAGGACAAG 1140 AAGAAAACAG CCGGGCGCAC CAGTCGTAGT AATCCCCCCA AACCAAAGGG AAAGCCTCCT 1200 GCTCCCAAAC CAGCCAGTCC CAAGAAGAAC ATTAAAACTA GGAGTGCCCA GAAGAGAACA 1260 AACCCGAAAA GAGTGTGAGC TAACTAGTTT CCAAAGCGGA GACTTCCGAC TTCCTTACAG 1320 GATGAGGCTG GGCATTGCCT GGGACAGCCT ATGTAAGGCC ATGTGCCCCT TGCCCTAACA 1380 ACTCACTGCA GTGCTCTTCA TAGACACATC TTGCAGCATT TTTCTTAAGG CTATGCTTCA 1440 GTTTTTCTTT GTAAGCCATC ACAAGCCATA GTGGTAGGTT TGCCCTTTGG TACAGAAGGT 1500 GAGTTAAAGC TGGTGGAAAA GGCTTATTGC ATTGCATTCA GAGTAACCTG TGTGCATACT 1560 CTAGAAGAGT AGGGAAAATA ATGCTTGTTA CAATTCGACC TAATATGTGC ATTGTAAAAT 1620 AAATGCCATA TTTCAAACAA AACACGTAAT TTTTTTACAG TATGTTTTAT TACCTTTTGA 1680 TATCTGTTGT TGCAATGTTA GTGATGTTTT AAAATGTGAT GAAAATATAA TGTTTTTAAG 1740 AAGGAACAGT AGTGGAATGA ATGTTAAAAG ATCTTTATGT GTTTATGGTC TGCAGAAGGA 1800 TTTTTGTGAT GAAAGGGGAT TTTTTGAAAA ATTAGAGAAG TAGCATATGG AAAATTATAA 1860 TGTGTTTTTT TACCAATGAC TTCAGTTTCT GTTTTTAGCT AGAAACTTAA AAACAAAAAT 1920 AATAATAAAG AAAAATAAAT AAAAAGGAGA GGCAGACAAT GTCTGGATTC CTGTTTTTTG 1980 GTTACCTGAT TTCCATGATC ATGATGCTTC TTGTCAACAC CCTCTTAAGC AGCACCAGAA 2040 ACAGTGAGTT TGTCTGTACC ATTAGGAGTT AGGTACTAAT TAGTTGGCTA ATGCTCAAGT 2100 ATTTTATACC CACAAGAGAG GTATGTCACT CATCTTACTT CCCAGGACAT CCACCCTGAG 2160 AATAATTTGA CAAGCTTAAA AATGGCCTTC ATGTGAGTGC CAAATTTTGT TTTTCTTCAT 2220 TTAAATATTT TCTTTGCCTA AATACATGTG AGAGGAGTTA AATATAAATG TACAGAGAGG 2280 AAAGTTGAGT TCCACCTCTG AAATGAGAAT TACTTGACAG TTGGGATACT TTAATCAGAA 2340 AAAAAGAACT TATTTGCAGC ATTTTATCAA CAAATTTCAT AATTGTGGAC AATTGGAGGC 2400 ATTTATTTTA AAAAACAATT TTATTGGCCT TTTGCTAACA CAGTAAGCAT GTATTTTATA 2460 AGGCATTCAA TAAATGCACA ACGCCCAAAG GAAATAAAAT CCTATCTAAT CCTACTCTCC 2520 ACTACACAGA GGTAATCACT ATTAGTATTT TGGCATATTA TTCTCCAGGT GTTTGCTTAT 2580 GCACTTATAA AATGATTTGA ACAAATAAAA CTAGGAACCT GTATACATGT GTTTCATAAC 2640 CTGCCTCCTT TGCTTGGCCC TTTATTGAGA TAAGTTTTCC TGTCAAGAAA . GCAGAAACCA 2700 TCTCATTTCT AACAGCTGTG TTATATTCCA TAGTATGCAT TACTCAACAA . ACTGTTGTGC 2760 TATTGGATAC TTAGGTGGTT TCTTCACTGA CAATACTGAA TAAACATCTC ! ACCGGAATTC
Seq ID NO : 64 Protein sequence Protein Accession ft : NP 003005 .1
51 MFLSILVALC LWLHLALGVR GAPCEAVRIP MCRHMPWNIT RMPNHLHHST QENAILAIEQ 60
YEELVDVNCS AVLRFFFCAM YAPICTLEFL HDPIKPCKSV CQRARDDCEP LMKMYNHSWP 120
ESLACDELPV YDRGVCISPE AIVTDLPEDV KWIDITPDMM VQERPLDVDC KRLSPDRCKC 180
KKVKPTLATY LSKNYSYVIH AKIKAVQRSG CNEVTTWDV KEIFKSSSPI PRTQVPLITN 240
SSCQCPHILP HQDVLIMCYE WRSRMMLLEN CLVEKWRDQL SKRSIQWEER LQEQRRTVQD 300
KKKTAGRTSR SNPPKPKGKP PAPKPASPKK NIKTRSAQKR TNPKRV
Seq ID NO: 65 DNA sequence
Nucleic Acid Accession # : BC010423 Coding sequence: 248. .1780
11 21 31 41 51
I I I I
CACAGCGTGG GAAGCAGCTC TGGGGGAGCT CGGAGCTCCC G 1ATCACGGCT TCTTGGGGGT 60
AGCTACGGCT GGGTGTGTAG AACGGGGCCG GGGCTGGGGC TGGGTCCCCT AGTGGAGACC 120
CAAGTGCGAG AGGCAAGAAC TCTGCAGCTT CCTGCCTTCT GGGTCAGTTC CTTATTCAAG 180
TCTGCAGCCG GCTCCCAGGG AGATCTCGGT GGAACTTCAG AAACGCTGGG CAGTCTGCCT 240
TTCAACCATG CCCCTGTCCC TGGGAGCCGA GATGTGGGGG CCTGAGGCCT GGCTGCTGCT 300
GCTGCTACTG CTGGCATCAT TTACAGGCCG GTGCCCCGCG GGTGAGCTGG AGACCTCAGA 360
CGTGGTAACT GTGGTGCTGG GCCAGGACGC AAAACTGCCC TGCTTCTACC GAβGGGACTC 420
CGGCGAGCAA GTGGGGCAAG TGGCATGGGC TCGGGTGGAC GCGGGCGAAG GCGCCCAGGA 480
ACTAGCGCTA CTGCACTCCA AATACGGGCT TCATGTGAGC CCGGCTTACG AGGGCCGCGT 540
GGAGCAGCCG CCGCCCCCAC GCAACCCCCT GGACGGCTCA GTGCTCCTGC GCAACGCAGT 600
GCAGGCGGAT GAGGGCGAGT ACGAGTGCCG GGTCAGCACC TTCCCCGCCG GCAGCTTCCA 660
GGCGCGGCTG CGGCTCCGAG TGCTGGTGCC TCCCCTGCCC TCACTGAATC CTGGTCCAGC 720
ACTAGAAGAG GGCCAGGGCC TGACCCTGGC AGCCTCCTGC ACAGCTGAGG GCAGCCCAGC 780
CCCCAGCGTG ACCTGGGACA CGGAGGTCAA AGGCACAACG TCCAGCCGTT CCTTCAAGCA 840
CTCCCGCTCT GCTGCCGTCA CCTCAGAGTT CCACTTGGTG CCTAGCCGCA GCATGAATGG 900
GCAGCCACTG ACTTGTGTGG TGTCCCATCC TGGCCTGCTC CAGGACCAAA GGATCACCCA 960
CATCCTCCAC GTGTCCTTCC TTGCTGAGGC CTCTGTGAGG GGCCTTGAAG ACCAAAATCT 1020
GTGGCACATT GGCAGAGAAG GAGCTATGCT CAAGTGCCTG AGTGAAGGGC AGCCCCCTCC 1080
CTCATACAAC TGGACACGGC TGGATGGGCC TCTGCCCAGT GGGGTACGAG TGGATGGGGA 1140
CACTTTGGGC TTTCCCCCAC TGACCACTGA GCACAGCGGC ATCTACGTCT GCCATGTCAG 1200
CAATGAGTTC TCCTCAAGGG ATTCTCAGGT CACTGTGGAT GTTCTTGACC CCCAGGAAGA 1260
CTCTGGGAAG CAGGTGGACC TAGTGTCAGC CTCβGTGGTG GTGGTGGGTG TGATCGCCGC 1320
ACTCTTGTTC TGCCTTCTGG TGGTGGTGGT GGTGCTCATG TCCCGATACC ATCGGCGCAA 1380
GGCCCAGCAG ATGACCCAGA AATATGAGGA GGAβCTGACC CTGACCAGGG AGAACTCCAT 1440
CCGGAGGCTG CATTCCCATC ACACGGACCC CAGGA6CCAG CCGGAGGAGA GTGTAGGGCT 1500
GAGAGCCGAG GGCCACCCTG ATAGTCTCAA GGACAACAGT AGCTGCTCTG TGATGAGTGA 1560
AGAGCCCGAG GGCCGCAGTT ACTCCACGCT GACCACGGTG AGGGAGATAG AAACACAGAC 1620
TGAACTGCTG TCTCCAGGCT CTGGGCGGGC CGAGGAGGAG GAAGATCAGG ATGAAGGCAT 1680
CAAACAGGCC ATGAAGCATT TTGTTCAGGA GAATGGGACC CTACGGGCCA AGCCCACGGG 1740
CAATGGCATC TACATCAATG GGCGGGGACA CCTGGTCTGA CCCAGGCCTG CCTCCCTTCC 1800
CTAGGCCTGG CTCCTTCTGT TGACATGGGA GATTTTAGCT CATCTTGGGG GCCTCCTTAA 1860
ACACCCCCAT TTCTTGCGGA AGATGCTCCC CATCCCACTG ACTGCTTGAC CTTTACCTCC 1920
AACCCTTCTG TTCATCGGGA GGGCTCCACC AATTGAGTCT CTCCCACCAT GCATGCAGGT 1980
CACTGTGTGT GTGCATGTGT GCCTGTGTGA GTGTTGACTG ACTGTGTGTG TGTGGAGGGG 2040
TGACTGTCCG TGGAGGGGTG ACTGTGTCCG TGGTGTGTAT TATGCTGTCA TATCAGAGTC 2100
AAGTGAACTG TGGTGTATGT GCCACGGGAT TTGAGTGGTT GCGTGGGCAA CACTGTCAGG 2160
GTTTGGCGTG TGTGTCATGT GGCTGTGTGT GACCTCTGCC TGAAAAAGCA GGTATTTTCT 2220
CAGACCCCAG AGCAGTATTA ATGATGCAGA GGTTGGAGGA GAGAGGTGGA GACTGTGGCT 2280
CAGACCCAGG TGTGCGGGCA TAGCTGGAGC TGGAATCTGC CTCCGGTGTG AGGGAACCTG 2340
TCTCCTACCA CTTCGGAGCC ATGGGGGCAA GTGTGAAGCA GCCAGTCCCT GGGTCAGCCA 2400
GAGGCTTGAA CTGTTACAGA AGCCCTCTGC CCTCTGGTGG CCTCTGGGCC TGCTGCATGT 2460
ACATATTTTC TGTAAATATA CATGCGCCGG GAGCTTCTTG CAGGAATACT GCTCCGAATC 2520
ACTTTTAATT TTTTTTCTTG CCCTTTCCAT TAGTTGTATT TTTTATTTAT 2580
TTTTATTTTT ATTTTTTTTT AGAGTTTGAG TCCAGCCTGG ACGATATAGC CAGACCCTGT 2640
CTGTAAAAAA ACCAAAACCC AAAAAAAAAA AAAAAAAAAA
Seq ID NO: 66 Protein sequence Protein Accession ft: AAH10423
11 21 31 41 51
I I I I I
MPLSLGAEMW GPEAWLLLLL LLASFTGRCP AGELETSDW TWLGQDAKL PCFYRGDSGE 60 QVGQVAWARV DAGEGAQELA LLHSKYGLHV SPAYEGRVEQ PPPPRNPLDG SVLLRNAVQA 120 DEGEYECRVS TFPAGSFQAR LRLRVLVPPL PSLNPGPALE EGQGLTLAAS CTAEGSPAPS 180 VTWDTEVKGT TSSRSFKHSR SAAVTSEFHL VPSRSMNGQP LTCWSHPGL LQDQRITHIL 240 HVSFLAEASV RGLEDQNLWH IGREGAMLKC LSEGQPPPSY NWTRLDGPLP SGVRVDGDTL 300 GFPPLTTEHS GIYVCHVSNE FSSRDSQVTV DVLDPQEDSG KQVDLVSASV WVGVIAALL 360 FCLLVWWL MSRYHRRKAQ QMTQKYEEEL TLTRENSIRR LHSHHTDPRS QPEESVGLRA 420 EGHPDSLKDN SSCSVMSEEP EGRSYSTLTT VREIETQTEL LSPGSGRAEE EEDQDEGIKQ 480 AMNHFVQENG TLRAKPTGNG IYINGRGHLV
Seq ID NO : 67 DNA sequence
Nucleic Acid Accession # : NM.001203
Coding sequence : 274 . .1782
11 21 31 41 51
I I I I I I
CGCGGGGCGC GGAGTCGGCG GGGCCTCGCG GGACGCGGGC AGTGCGGAGA CCGCGGCGCT 60 GAGGACGCGG GAGCCGGGAG CGCACGCGCG GGGTGGAGTT CAGCCTACTC TTTCTTAGAT 120 GTGAAAGGAA AGGAAGATCA TTTCATGCCT TGTTGATAAA GGTTCAGACT TCTGCTGATT 180 CATAACCATT TGGCTCTGAG CTATGACAAG AGAGGAAACA AAAAGTTAAA CTTACAAGCC 240 TGCCATAAGT GAGAAGCAAA CTTCCTTGAT AACATGCTTT TGCGAAGTGC AGGAAAATTA 300 AATGTGGGCA CCAAGAAAGA GGATGGTGAG AGTACAGCCC CCACCCCCCG TCCAAAGGTC 360 TTGCGTTGTA AATGCCACCA CCATTGTCCA GAAGACTCAG TCAACAATAT TTGCAGCACA 420 GACGGATATT GTTTCACGAT GATAGAAGAG GATGACTCTG GGTTGCCTGT GGTCACTTCT 480 GGTTGCCTAG GACTAGAAGG CTCAGATTTT CAGTGTCGGG ACACTCCCAT TCCTCATCAA 540 AGAAGATCAA TTGAATGCTG CACAGAAAGG AACGAATGTA ATAAAGACCT ACACCCTACA 600 CTGCCTCCAT TGAAAAACAG AGATTTTGTT GATGGACCTA TACACCACAG GGCTTTACTT 660 ATATCTGTGA CTGTCTGTAG TTTGCTCTTG GTCCTTATCA TATTATTTTG TTACTTCCGG 720 TATAAAAGAC AAGAAACCAG ACCTCGATAC AGCATTGGGT TAGAACAGGA TGAAACTTAC 780 ATTCCTCCTβ GAGAATCCCT GAGAGACTTA ATTGAGCAGT CTCAGAGCTC AGGAAGTGGA 840 TCAGGCCTCC CTCTGCTGGT CCAAAGGACT ATAGCTAAGC AGATTCAGAT GGTGAAACAG 900 ATTGGAAAAG GTCGCTATGG GGAAGTTTGG ATGGGAAAGT GGCGTGGCGA AAACGTAGCT 960 GTGAAAGTGT TCTTCACCAC AGAGGAAGCC AGCTGGTTCA GAGAGACAGA AATATATCAβ 1020 ACAGTGTTGA TGAGGCATGA AAACATTTTG GGTTTCATTG CTGCAGATAT CAAAGGGACA 1080 GGGTCCTGGA CCCAGTTGTA CCTAATCACA GACTATCATG AAAATGGTTC CCTTTATGAT 1140 TATCTGAAGT CCACCACCCT AGACGCTAAA TCAATGCTGA AGTTAGCCTA CTCTTCTGTC 1200 AGTGGCTTAT GTCATTTACA CACAGAAATC TTTAGTACTC AAGGCAAACC AGCAATTGCC 1260 CATCGAGATC TGAAAAGTAA AAACATTCTG GTGAAGAAAA ATGGAACTTG CTGTATTGCT 1320 GACCTGGGCC TGGCTGTTAA ATTTATTAGT GATACAAATG AAGTTGACAT ACCACCTAAC 1380 ACTCGAGTTG GCACCAAACG CTATATGCCT CCAGAAGTGT TGGACGAGAG CTTGAACAGA 1440 AATCACTTCC AGTCTTACAT CATGGCTGAC ATGTATAGTT TTGGCCTCAT CCTTTGGGAG 1500 GTTGCTAGGA GATGTGTATC AGGAGGTATA GTGGAAGAAT ACCAGCTTCC TTATCATGAC 1560 CTAGTGCCCA GTGACCCCTC TTATGAGGAC ATGAGGGAGA TTGTGTGCAT CAAGAAGTTA 1620 CGCCCCTCAT TCCCAAACCG GTGGAGCAGT GATGAGTGTC TAAGGCAGAT GGGAAAACTC 1680 ATGACAGAAT GCTGGGCTCA CAATCCTGCA TCAAGGCTGA CAGCCCTGCG GGTTAAGAAA 1740 ACACTTGCCA AAATGTCAGA GTCCCAGGAC ATTAAACTCT GATAGGAGAG GAAAAGTAAG 1800 CATCTCTGCA GAAAGCCAAC AGGTACTCTT CTGTTTGTGG GCAGAGCAAA AGACATCAAA 1860 TAAGCATCCA CAGTACAAGC CTTGAACATC GTCCTGCTTC CCAGTGGGTT CAGACCTCAC 1920 CTTTCAGGGA GCGACCTGGG CAAAGACAGA GAAGCTCCCA GAAGβAGAGA TTGATCCGTG 1980 TCTGTTTGTA GGCGGAGAAA CCGTTGGGTA ACTTGTTCAA GATATGATGC AT
Seq ID NO: 68 Protein sequence Protein Accession ft: NP 001194
11 21 31 41 51
I I I I
MLLRSAGKLN V 1GTKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED 60 DSGLPWTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD 120 GPIHHRALLI SVTVCSLLLV LIILFCYFRY KRQETRPRYS IGLEQDETYI PPGESLRDLI 180 EQSQSSGSGS GLPLLVQRTI AKQIQMVKQI GKGRYGEVWM GKWRGEKVAV KVFFTTEEAS 240 WFRETEIYQT VLMRHENILG FIAADIKGTG SWTQLYLITD YHENGSLYDY LKSTTLDAKS 300 MLKLAYSSVS GLCHLHTEIF STQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVKFISD 360 TNEVDIPPNT RVGTKRYMPP EVLDESLNRN HFQSYIMADM YSFGLILWEV ARRCVSGGIV 420 EEYQLPYHDL VPSDPSYEDM REIVCIKKLR PSFPNRWSSD ECLRQMGKLM TECWAHNPAS 480 RLTALRVKKT LAKMSESQDI KL
Seq ID NO: 69 DNA sequence Nucleic Acid Accession ft: Eos sequence Coding seguence: 166..1737
11 21
TTGGGGGTTT ATTCTCTTCC CTTCTAACTT GACAGGGTCT TGCTCTGTCA TTCAGGCAAG 60
AGTGCAGTAG TGTGATCACT TCTTACTGCC GCCTCAAGCT TCCAGCCTCA AGTCAAGCAA 120
TCCTCCCACC TCAGCCACCC AAGTGGCTGG GACTACAGAT TAAGAATGAC CCAAAATAAA 180
TTAAAGCTTT GTTCCAAAGC CAATGTGTAT ACTGAAGTGC CTGATGGAGG ATGGGGCTGG 240
GCGGTAGCTG TTTCATTTTT CTTCGTTGAA GTCTTCACCT ACGGCATCAT CAAGACATTT 300
GGTGTCTTCT TTAATGACTT AATGGACAGT TTTAATGAAT CCAATAGCAG GATCTCATGG 360
ATAATCTCAA TCTGTGTGTT TGTCTTAACA TTTTCAGCTC CCCTCGCCAC AGTCCTGAGC 420
AATCGTTTCG GACACCGTCT GGTAGTGATG TTGGGGGGGC TACTTGTCAG CACCGGGATG 480
GTGGCCGCCT CCTTCTCACA AGAGGTTTCT CATATGTACG TCGCCATCGG CATCATCTCT 540
GGTCTGGGAT ACTGCTTTAG TTTTCTCCCA ACTGTAACCA TCCTATCACA ATATTTTGGC 600
AAAAGACGTT CCATAGTCAC TGCAGTTGCT TCCACAGGAG AATGTTTCGC TGTGTTTGCT 660
TTCGCACCAG CAATCATGGC TCTGAAGGAG CGCATTGGCT GGAGATACAG CCTCCTCTTC 720
GTGGGCCTAC TACAGTTAAA CATTGTCATC TTCGGAGCAC TGCTCAGACC CATCTTTATC 780
AGAGGACCAG CGTCACCGAA AATAGTCATC CAGGAAAATC GGAAAGAAGC GCAGTATATG 840
CTTGAAAATG AGAAAACACG AACCTCAATA GACTCCATTG ACTCAGGAGT AGAACTAACT 900
ACCTCACCTA AAAATGTGCC TACTCACACT AACCTGGAAC TGGAGCCGAA GGCCGACATG 960
CAGCAGGTCC TGGTGAAGAC CAGCCCCAGG CCAAGCGAAA AGAAAGCCCC GCTATTAGAC 1020
TTCTCCATTT TGAAAGAGAA AAGTTTTATT TGTTATGCAT TATTTGGTCT CTTTGCAACA 1080
CTGGGATTCT TTGCACCTTC CTTGTACATC ATTCCTCTGG GCATTAGTCT GGGCATTGAC 1140
CAGGACCGCG CTGCTTTTTT ATTATCTACG ATGGCCATTG CAGAAGTTTT CGGAAGGATC 1200
GGAGCTGGTT TTGTCCTCAA CAGGGAGCCC ATTCGTAAGA TTTACATTGA GCTCATCTGC 1260
GTCATCTTAT TGACTGTGTC TCTGTTTGCC TTTACTTTTG CTACTGAATT CTGGGGTCTA 1320
ATGTCATGCA GCATATTTTT TGGGTTTATG GTTGGAACAA TAGGAGGGAC TCACATTCCA 1380
CTGCTTGCTG AGGATGATGT CGTGGGCATT GAGAAGATGT CTTCTGCAGC TGGGGTCTAC 1440
ATCTTCATTC AGAGCATAGC AGGACTGGCT GGACCGCCCC TTGCAGGTTT GTTGGTGGAC 1500
CAAAGTAAGA TCTACAGCAG GGCCTTCTAC TCCTGCGCAG CTGGCATGGC CCTGGCTGCT 1560
GTGTGCCTCG CCCTGGTGAG ACCGTGTAAG ATGGGACTGT GCCAGCATCA TCACTCAGGT 1620
GAAACAAAGG TAGTGAGCCA TCGTGGGAAG ACTTTACAGG ACATACCTGA AGACTTTCTG 1680
GAAATGGATC TTGCAAAAAA TGAGCACAGA GTTCACGTGC AAATGGAGCC GGTATGACAC 1740
ACTTTCTTAC AACAACAGCC ACTGTGTTGG CTGGAGAGGG ATGGGGTGGG CCCAACGGGG 1800
ACACAAGGAG GCAGAGGAGC TAACCCCTCT ACTCCACTTT CAAAACTACA TTTTAAAGGG 1860 AATGTGTATG TGAAGAGCAC TACCAACATC GCTTTTGTTT TGTTTTGTTT TGTTTTAAGC 1920
TTTTTTTTTT TGCTTGTTTT TAAAGCCAAA ACAAAAAACA ACCAAGCACT CTTCCATATA 1980
TAAATCTGGC TGTATTCAGT AGCAATACAA GAGATATGTA GAAAGACTCT TTGGTTCACA 2040
TTCCGATATT AAAATAGTGA CATGAACTGG CAAAGTGGTT TTAAAAGCTT TCACGTGGGA 2100
TAAATGATTT TCTTTTTTTC TTTTCTTTCT TCCTATGGTC TTGTCTGAAT AAACTACTCT 2160 CCTGAATAAA ACAACATCCA ACCCAGGTCA TTGAAATGAA ATTGGCCAGT C
Seq ID NO: 70 Protein sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MTQNKLKLCS KANVYTEVPD GGWGWAVAVS FFFVEVFTYG IIKTFGVFFN DLMDSFNESN 60
SRISWIISIC VFVLTFSAPL ATVLSNRFGH RLWMLGGLL VSTGMVAASF SQEVSHMYVA 120 IGIISGLGYC FSFLPTVTIL SQYFGKRRSI VTAVASTGEC FAVFAFAPAI MALKERIGWR 180
YSLLFVGLLQ LNIVIFGALL RPIFIRGPAS PKIVIQENRK EAQYMLENEK TRTSIDSIDS 240
GVELTTSPKN VPTHTNLELE PKADMQQVLV KTSPRPSEKK APLLDFSILK EKSFICYALF 300
GLFATLGFFA PSLYIIPLGI SLGIDQDRAA FLLΞTMAIAE VFGRIGAGFV LNREPIRKIY 360
IELICVILLT VSLFAFTFAT EFWGLMSCSI FFGFMVGTIG GTHIPLLAED DWGIEKMSS 420 AAGVYIFIQS IAGLAGPPLA GLLVDQSKIY SRAFYSCAAG MALAAVCLAL VRPCKMGLCQ 480 HHHSGETKW SHRGKTLQDI PEDFLEMDLA KNEHRVHVQM EPV
Seq ID NO: 71 DNA sequence Nucleic Acid Accession ft: NM_004694 Coding sequence: 166..1737
1 11 21 31 41 51
I I I I I I
TTGGGGGTTT ATTCTCTTCC CTTCTAACTT GACAGGGTCT TGCTCTGTCA TTCAGGCAAG 60
AGTGCAGTAG TGTGATCACT TCTTACTGCC GCCTCAAGCT TCCAGCCTCA ACTCAAGCAA 120
TCCTCCCACC TCAGCCACCC AAGTGGCTGG GACTACAGAT TAAGAATGAC CCAAAATAAA 180
TTAAAGCTTT GTTCCAAAGC CAATGTGTAT ACTGAAGTGC CTGATGGAGG ATGGGGCTGG 240
GCGGTAGCTG TTTCATTTTT CTTCGTTGAA GTCTTCACCT ACGGCATCAT CAAGACATTT 300
GGTGTCTTCT TTAATGACTT AATGGACAGT TTTAATGAAT CCAATAGCAG GATCTCATGG 360
ATAATCTCAA TCTGTGTGTT TGTCTTAACA TTTTCAGCTC CCCTCGCCAC AGTCCTGAGC 420
AATCGTTTCG GACACCGTCT GGTAGTGATG TTGGGGGGGC TACTTGTCAG CACCGGGATG 480
GTGGCCGCCT CCTTCTCACA AGAGGTTTCT CATATGTACG TCGCCATCGG CATCATCTCT 540
GGTCTGGGAT ACTGCTTTAG TTTTCTCCCA ACTGTAACCA TCCTATCACA ATATTTTGGC 600
AAAAGACGTT CCATAGTCAC TGCAGTTGCT TCCACAGGAG AATGTTTCGC TGTGTTTGCT 660
TTCGCACCAG CAATCATGGC TCTGAAGGAG CGCATTGGCT GGAGATACAG CCTCCTCTTC 720
GTGGGCCTAC TACAGTTAAA CATTGTCATC TTCGGAGCAC TGCTCAGACC CATCATTATC 780
AGAGGACCAG CGTCACCGAA AATAGTCATC CAGGAAAATC GGAAAGAAGC GCAGTATATG 840
CTTGAAAATG AGAAAACACG AACCTCAATA GACTCCATTG ACTCAGGAGT AGAACTAACT 900
ACCTCACCTA AAAATGTGCC TACTCACACT AACCTGGAAC TGGAGCCGAA GGCCGACATG 960
CAGCAGGTCC TGGTGAAGAC CAGCCCCAGG CCAAGCGAAA AGAAAGCCCC GCTATTAGAC 1020
TTCTCCATTT TGAAAGAGAA AAGTTTTATT TGTTATGCAT TATTTGGTCT CTTTGCAACA 1080
CTGGGATTCT TTGCACCTTC CTTGTACATC ATTCCTCTGG GCATTAGTCT GGGCATTGAC 1140
CAGGACCGCG CTGCTTTTTT ATTATCTACG ATGGCCATTG CAGAAGTTTT CGGAAGGATC 1200
GGAGCTGGTT TTGTCCTCAA CAGGGAGCCC ATTCGTAAGA TTTACATTGA GCTCATCTGC 1260
GTCATCTTAT TGACTGTGTC TCTGTTTGCC TTTACTTTTG CTACTGAATT CTGGGGTCTA 1320
ATGTCATGCA GCATATTTTT TGGGTTTATG GTTGGAACAA TAGGAββACT CACATTCCAC 1380
TGCTTGCTGA AGATGATGTC GTGGGCATTG CAGAAGATGT CTTCTGCAGC TGGGGTCTAC 1440
ATCTTCATTC AGAGCATAGC AGGACTGGCT GGACCGCCCC TTGCAGGTTT GTTGGTGGAC 1500
CAAAGTAAGA TCTACAGCAG GGCCTTCTAC TCCTGCGCAG CTGGCATGGC CCTGGCTGCT 1560
GTGTGCCTCG CCCTGGTGAG ACCGTGTAAG ATGGGACTGT GCCAGCGTCA TCACTCAGGT 1620
GAAACAAAGG TAGTGAGCCA TCGTGGGAAG ACTTTACAGG ACATACCTGA AGACTTTCTG 1680
GAAATGGATC TTGCAAAAAA TGAGCACAGA GTTCACGTGC AAATGGAGCC GGTATGACAC 1740
ACTTTCTTAC AACAACAGCC ACTGTGTTGG CTGGAGAGGG ATGGGGTGGG CCCAACGGGG 1800
ACACAAGGAG GCAGAGGAGC TAACCCCTCT ACTCCACTTT CAAAACTACA TTTTAAAGGβ 1860
AATGTGTATG TGAAGAGCAC TACCAACATC GCTTTTGTTT TGTTTTGTTT TGTTTTAAGC 1920
TTTTTTTTTT TGCTTGTTTT TAAAGCCAAA ACAAAAAACA ACCAAGCACT CTTCCATATA 1980
TAAATCTGGC TGTATTCAGT AGCAATACAA GAGATATGTA GAAAGACTCT TTGGTTCACA 2040
TTCCGATATT AAAATAGTGA CATGAACTGG CAAAGTGGTT TTAAAAGCTT TCACGTGGGA 2100
TAAATGATTT TCTTTTTTTC TTTTCTTTCT TCCTATGGTC TTGTCTGAAT AAACTACTCT 2160 CCTGAATAAA ACAACATCCA ACCCAGGTCA TTGAAATGAA ATTGGCCAGT C
Seq ID NO: 72 Protein sequence Protein Accession #: NP_004685
1 11 21 31 41 51
M ITQNKLKLCS KIANVYTEVPD GIGWGWAVAVS FIFFVEVFTYG IIIKTFGVFFN DILMDSFNESN 60
SRISWIISIC VFVLTFSAPL ATVLSNRFGH RLWMLGGLL VSTGMVAASF SQEVSHMYVA 120
IGIISGLGYC FSFLPTVTIL SQYFGKRRSI VTAVASTGEC FAVFAFAPAI MALKERIGWR 180
YSLLFVGLLQ LNIVIFGALL RPIIIRGPAS PKIVIQENRK EAQYMLENEK TRTSIDSIDS 240
GVELTTSPKN VPTHTNLELE PKADMQQVLV KTSPRPSEKK APLLDFSILK EKSFICYALF 300
GLFATLGFFA PSLYIIPLGI SLGIDQDRAA FLLSTMAIAE VFGRIGAGFV LNREPIRKIY 360
IELICVILLT VSLFAFTFAT EFWGLMSCSI FFGFMVGTIG GLTFHCLLKM MSWALQKMSS 420
AAGVYIFIQS IAGLAGPPLA GLLVDQSKIY SRAFYSCAAG MALAAVCLAL VRPCKMGLCQ 480 RHHSGETKW SHRGKTLQDI PEDFLEMDLA KNEHRVHVQM EPV
Seq ID NO: 73 DNA sequence
Nucleic Acid Accession ft: NM_002184.1
Coding sequence: 256..3012 1 11 21 31 41 51
I I I I I I
GAGCAGCCAA AAGGCCCGCG GAGTCGCGCT GGGCCGCCCC GGCGCAGCTG AACCGGGGGC 60
CGCGCCTGCC AGGCCGACGG GTCTGGCCCA GCCTGGCGCC AAGGGGTTCG TGCGCTGTGG 120
AGACGCGGAG GGTCGAGGCG GCGCGGCCTG AGTGAAACCC AATGGAAAAA GCATGACATT 180
TAGAAGTAGA AGACTTAGCT TCAAATCCCT ACTCCTTCAC TTACTAATTT TGTGATTTGG 240
AAATATCCGC GCAAGATGTT GACGTTGCAG ACTTGGGTAG TGCAAGCCTT GTTTATTTTC 300
CTCACCACTG AATCTACAGG TGAACTTCTA GATCCATGTG GTTATATCAG TCCTGAATCT 360
CCAGTTGTAC AACTTCATTC TAATTTCACT GCAGTTTGTG TGCTAAAGGA AAAATGTATG 420
GATTATTTTC ATGTAAATGC TAATTACATT GTCTGGAAAA CAAACCATTT TACTATTCCT 480
AAGGAGCAAT ATACTATCAT AAACAGAACA GCATCCAGTG TCACCTTTAC AGATATAGCT 540
TCATTAAATA TTCAGCTCAC TTGCAACATT CTTACATTCG GACAGCTTGA ACAGAATGTT 600
TATGGAATCA CAATAATTTC AGGCTTGCCT CCAGAAAAAC CTAAAAATTT GAGTTGCATT 660
GTGAACGAGG GGAAGAAAAT GAGGTGTGAG TGGGATGGTG GAAGGGAAAC ACACTTGGAG 720
AGAAACTTCA CTTTAAAATC TGAATGGGCA ACACACAAGT TTGCTGATTG CAAAGCAAAA 780
CGTGACACCC CCACCTCATG CACTGTTGAT TATTCTACTG TGTATTTTGT CAACATTGAA 840
GTCTGGGTAG AAGCAGAGAA TGCCCTTGGG AAGGTTACAT CAGATCATAT CAATTTTGAT 900
CCTGTATATA AAGTGAAGCC CAATCCGCCA CATAATTTAT CAGTGATCAA CTCAGAGGAA 960
CTGTCTAGTA TCTTAAAATT GACATGGACC AACCCAAGTA TTAAGAGTGT TATAATACTA 1020
AAATATAACA TTCAATATAG GACCAAAGAT GCCTCAACTT GGAGCCAGAT TCCTCCTGAA 1080
GACACAGCAT CCACCCGATC TTCATTCACT GTCCAAGACC TTAAACCTTT TACAGAATAT 1140
GTGTTTAGGA TTCGCTGTAT GAAGGAAGAT GGTAAGGGAT ACTGGAGTGA CTGGAGTGAA 1200
GAAGCAAGTG GGATCACCTA TGAAGATAGA CCATCTAAAG CACCAAGTTT CTGGTATAAA 1260
ATAGATCCAT CCCATACTCA AGGCTACAGA ACTGTACAAC TCGTGTGGAA GACATTGCCT 1320
CCTTTTGAAG CCAATGGAAA AATCTTGGAT TATGAAGTGA CTCTCACAAG ATGGAAATCA 1380
CATTTACAAA ATTACACAGT TAATGCCACA AAACTGACAG TAAATCTCAC AAATGATCGC 1440
TATCTAGCAA CCCTAACAGT AAGAAATCTT GTTGGCAAAT CAGATGCAGC TGTTTTAACT 1500
ATCCCTGCCT GTGACTTTCA AGCTACTCAC CCTGTAATGG ATCTTAAAGC ATTCCCCAAA 1560
GATAACATGC TTTGGGTGGA ATGGACTACT CCAAGGGAAT CTGTAAAGAA ATATATACTT 1620
GAGTGGTGTG TGTTATCAGA TAAAGCACCC TGTATCACAG ACTGGCAACA AGAAGATGGT 1680
ACCGTGCATC GCACCTATTT AAGAGGGAAC TTAGCAGAGA GCAAATGCTA TTTGATAACA 1740
GTTACTCCAG TATATGCTGA TGGACCAGGA AGCCCTGAAT CCATAAAGGC ATACCTTAAA 1800
CAAGCTCCAC CTTCCAAAGG ACCTACTGTT CGGACAAAAA AAGTAGGGAA AAACGAAGCT 1860
GTCTTAGAGT GGGACCAACT TCCTGTTGAT GTTCAGAATG GATTTATCAG AAATTATACT 1920
ATATTTTATA GAACCATCAT TGGAAATGAA ACTGCTGTGA ATGTGGATTC TTCCCACACA 1980
GAATATACAT TGTCCTCTTT GACTAGTGAC ACATTGTACA TGGTACGAAT GGCAGCATAC 2040
ACAGATGAAG GTGGGAAGGA TGGTCCAGAA TTCACTTTTA CTACCCCAAA GTTTGCTCAA 2100
GGAGAAATTG AAGCCATAGT CGTGCCTGTT TGCTTAGCAT TCCTATTGAC AACTCTTCTG 2160
GGAGTGCTGT TCTGCTTTAA TAAGCGAGAC CTAATTAAAA AACACATCTG GCCTAATGTT 2220
CCAGATCCTT CAAAGAGTCA TATTGCCCAG TGGTCACCTC AGACTCCTCC AAGGCACAAT 2280
TTTAATTCAA AAGATCAAAT GTATTCAGAT GGCAATTTCA CTGATGTAAG TGTTGTGGAA 2340
ATAGAAGCAA ATGACAAAAA GCCTTTTCCA GAAGATCTGA AATCATTGGA CCTGTTCAAA 2400
AAGGAAAAAA TTAATACTGA AGGACACAGC AGTGGTATTG GGGGGTCTTC ATGCATGTCA 2460
TCTTCTAGGC CAAGCATTTC TAGCAGTGAT GAAAATGAAT CTTCACAAAA CACTTCGAGC 2520
ACTGTCCAGT ATTCTACCGT GGTACACAGT GGCTACAGAC ACCAAGTTCC GTCAGTCCAA 2580
GTCTTCTCAA GATCCGAGTC TACCCAGCCC TTGTTAGATT CAGAGGAGCG GCCAGAAGAT 2640
CTACAATTAG TAGATCATGT AGATGGCGGT GATGGTATTT TGCCCAGGCA ACAGTACTTC 2700
AAACAGAACT GCAGTCAGCA TGAATCCAGT CCAGATATTT CACATTTTGA AAGGTCAAAG 2760
CAAGTTTCAT CAGTCAATGA GGAAGATTTT GTTAGACTTA AACAGCAGAT TTCAGATCAT 2820
ATTTCACAAT CCTGTGGATC TGGGCAAATG AAAATGTTTC AGGAAGTTTC TGCAGCAGAT 2880
GCTTTTGGTC CAGGTACTGA GGGACAAGTA GAAAGATTTG AAACAGTTGG CATGGAGGCT 2940
GCGACTGATG AAGGCATGCC TAAAAGTTAC TTACCACAGA CTGTACGGCA AGGCGGCTAC 3000
ATGCCTCAGT GAAGGACTAG TAGTTCCTGC TACAACTTCA GCAGTACCTA TAAAGTAAAG 3060 CTAAAATGAT TTTATCTGTG AATTC
Seq ID NO : 74 Protein sequence Protein Accession # : NP 002175 . 1
11 21 31 41 51
I I I I I
MLTLQTWWQ ALFIFLTTES TGELLDPCGY ISPESPWQL HSNFTAVCVL KEKCMDYFHV 60 NANYIVWKTN HFTIPKEQYT IINRTASSVT FTDIASLNIQ LTCNILTFGQ LEQNVYGITI 120 ISGLPPEKPK NLSCIVNEGK KMRCEWDGGR ETHLETNFTL KSEWATHKFA DCKAKRDTPT 180 SCTVDYSTVY FVNIEVWVEA ENALGKVTSD HINFDPVYKV KPNPPHNLSV INSEELSSIL 240 KLTWTNPSIK SVIILKYNIQ YRTKDASTWS QIPPEDTAST RSSFTVQDLK PFTEYVFRIR 300 CMKEDGKGYW SDWSEEASGI TYEDRPSKAP SFWYKIDPSH TQGYRTVQLV WKTLPPFEAN 360 GKILDYEVTL TRWKSHLQNY TVNATKLTVN LTNDRYLATL TVRNLVGKSD AAVLTIPACD 420 FQATHPVMDL KAFPKDNMLW VEWTTPRESV KKYILEWCVL SDKAPCITDW QQEDGTVHRT 480 YLRGNLAESK CYLITVTPVY ADGPGSPESI KAYLKQAPPS KGPTVRTKKV GKNEAVLEWD 540 QLPVDVQNGF IRNYTIFYRT IIGNETAVNV DSSHTEYTLS SLTSDTLYMV RMAAYTDEGG 600 KDGPEFTFTT PKFAQGEIEA IWPVCLAFL LTTLLGVLFC FNKRDLIKKH IWPNVPDPSK 660 SHIAQWSPHT PPRHNFNSKD QMYSDGNFTD VSWEIEAND KKPFPEDLKS LDLFKKEKIN 720 TEGHSSGIGG SSCMSSSRPS ISSSDENESS QNTSSTVQYS TWHSGYRHQ VPSVQVFSRS 780 ESTQPLLDSE ERPEDLQLVD HVDGGDGILP RQQYFKQNCS QHESSPDISH FERSKQVSSV 840 NEEDFVRLKQ QISDHISQSC GSGQMKMFQE VSAADAFGPG TEGQVERFET VGMEAATDEG 900 MPKSYLPQTV RQGGYMPQ
Seq ID NO: 75 DNA sequence
Nucleic Acid Accession ft: NM_022131
Coding sequence: 11..2878
1 11 21 31 41 51
I I I I I I
TGCTGCGAGG ATGCTGCCTG GGCGGCTGTG CTGGGTGCCG CTCCTGCTGG CGCTGGGCGT GGGGAGCGGC AGCGGCGGTG GCGGGGACAG CCGGCAGCGC CGCCTCCTCG CGGCTAAAGT 120
CAATAAGCAC AAGCCATGGA TCGAGACTTC ATATCATGGA GTCATAACTG AGAACAATGA 180
CACAGTCATT TTGGACCCAC CACTCGTAGC CCTGGATAAA GATGCACCGG TTCCTTTTGC 240
AGGGGAAATC TGTGCGTTCA AGATCCATGG CCAGGAGCTG CCCTTTGAGG CTGTGGTGCT 300
CAACAAGACA TCAGGAGAGG GCCGGCTCCG TGCCAAGAGC CCCATTGACT GTGAGTTGCA 360
GAAGGAGTAC ACATTCATCA TCCAGGCCTA TGACTGTGGT GCTGGGCCCC ACGAGACAGC 420
CTGGAAAAAG TCACACAAGG CCGTGGTCCA TATACAGGTG AAGGATGTCA ACGAGTTTGC 480
TCCCACCTTC AAAGAGCCAG CCTACAAGGC TGTTGTGACG GAGGGCAAGA TCTATGACAG 540
CATTCTGCAG GTGGAGGCCA TTGACGAGGA CTGCTCCCCA CAGTACAGCC AGATCTGCAA 600
CTATGAAATC GTCACCACAG ATGTGCCTTT TGCCATCGAC AGAAATGGCA ACATCAGGAA 660
CACTGAGAAG CTGAGCTATG ACAAACAACA CCAGTATGAG ATCCTGGTGA CCGCCTACGA 720
CTGTGGACAG AAGCCCGCTG CTCAGGACAC CCTGGTGCAG GTGGATGTGA AGCCAGTTTG 780
CAAGCCTGGC TGGCAAGACT GGACCAAGAG GATTGAGTAC CAGCCTGGCT CCGGGAGCAT 840
GCCCCTGTTC CCCAGCATCC ACCTGGAGAC GTGCβATGGA GCCGTGTCTT CCCTCCAGAT 900
CGTCACAGAG CTGCAGACTA ATTACATTGG GAAGGGTTGT GACCGGGAGA CCTACTCTGA 960
GAAATCCCTT CAGAAGTTAT GTGGAGCCTC CTCTGGCATC ATTGACCTCT TGCCATCCCC 1020
TAGCGCTGCC ACCAACTGGA CTGCAGGACT GCTGβTGGAC AGCAGTGAGA TGATCTTCAA 1080
GTTTGACGGC AGGCAGGGTG CCAAAATCCC CGATGGGATT GTGCCCAAGA ACCTGACCGA 1140
TCAGTTCACC ATCACCATGT GGATGAAACA CGGCCCCAGC CCTGGTGTGA GAGCCGAGAA 1200
GGAAACCATC CTCTGCAACT CAGACAAAAC CGAAATGAAC CGGCATCACT ATGCCCTGTA 1260
TGTGCACAAC TGCCGCCTCG TCTTTCTCTT GCGGAAGGAC TTCGACCAGG CTGACACCTT 1320
TCGCCCCGCG GAGTTCCACT GGAAGCTGGA TCAGATTTGT GACAAAGAGT GGCACTACTA 1380
TGTCATCAAT GTGGAGTTTC CTGTGGTAAC CTTATACATG GATGGAGCAA CATATGAACC 1440
ATACCTGGTG ACCAACGACT GGCCCATTCA TCCATCTCAC ATAGCCATGC AACTCACAGT 1500
CGGCGCTTGT TGGCAAGGAG GAGAAGTCAC CAAACCACAG TTTGCTCAGT TCTTTCATGG 1560
AAGCCTGGCC AGTCTCACCA TCCGCCCTGG CAAAATGGAA AGCCAGAAGG TGATCTCCTG 1620
CCTGCAGGCC TGCAAGGAAG GGCTGGACAT TAATTCCTTG GAAAGCCTTβ GCCAAGGAAT 1680
AAAGTATCAC TTCAACCCCT CGCAGTCCAT CCTGGTGATG GAAGGTGACG ACATTGGGAA 1740
CATTAACCGT GCTCTCCAGA AAGTCTCCTA CATCAACTCC AGGCAGTTCC CAACGGCGGG 1800
TGTGCGGCGC CTCAAAGTAT CCTCCAAAGT CCAGTGCTTT GGGGAAGACG TATGCATCAG 1860
TATCCCTGAG GTAGATGCCT ATGTGATGGT CCTGCAGGCC ATCGAGCCCC GGATCACCCT 1920
CCGGGGCACA GACCACTTCT GGAGACCTGC TGCCCAGTTT GAAAGTGCCA GGGGAGTGAC 1980
CCTCTTCCCT GATATCAAGA TTGTGAGCAC CTTCGCCAAA ACCGAAGCCC CCGGGGACGT 2040
GAAAACCACA GACCCCAAAT CAGAAGTCTT AGAGGAAATG CTTCATAACT TAGATTTCTG 2100
TGACATTTTG GTGATCGGAG GGGACTTGGA CCCAAGGCAG GAGTGCTTGG AGCTCAACCA 2160
CAGTGAGCTC CACCAACGAC ACCTGGATGC CACTAATTCT ACTGCAGGCT ACTCCATCTA 2220
CGGTGTGGGC TCCATGAGCC GCTATGAGCA GGTGCTACAT CACATCCGCT ACCGCAACTG 2280
GCGTCCGGCT TCCCTTGAGG CCCGGCGTTT CCGGATTAAG TGCTCAGAAC TCAATGGGCG 2340
CTACACTAGC AATGAGTTCA ACTTGGAGGT CAGCATCCTT CATGAAGACC AAGTCTGAGA 2400
TAAGGAGCAT GTCAATCATC TGATTGTGCA GCCTCCCTTC CTCCAGTCTG TCCATCATCC 2460
TGAGTCCCGG AGTAGCATCC AGCACAGTTC AGTGGTCCCA AGCATTGCCA CAGTGGTCAT 2520
CATCATCTCC GTGTGCATGC TTGTGTTTGT CGTGGCCATG GGTGTGTACC GGGTCCGGAT 2580
CGCCCACCAG CACTTCATCC AGGAGACTGA GGCTGCCAAG GAATCTGAGA TGGACTGGGA 2640
CGATTCTGCG CTGACTATCA CAGTCAACCC CATGGAGAAA CATGAAGGAC CAGGGCATGG 2700
GGAAGATGAG ACTGAGGGAG AAGAGGAGGA AGAAGCCGAG GAAGAAATGA GCTCCAGCAG 2760
TGGCTCTGAC GACAGCGAAG AGGAGGAGGA GGAGGAAGGG ATGGGCAGAG GCAGACATGG 2820
GCAGAATGGA GCCAGGCAAG CCCAGCTGGA GTGGGATGAC TCCACCCTCC CCTACTAGTG 2880
CCCAGGGGTC TGCTGCCTGG CCCACATGTC CCTTTTGTAA ACCCTGACCC AGTGTATGCC 2940
CATGTCTATC ATACCTCACC TCTGATGTCT GTGACATGTC TGGGAAGGCC TTCTCCAGCT 3000
TCCTGGAGCC CACCCTTTAA GCCTTGGGCA CTCCCTGTGT TTCATCCATG GGGAAGTTCC 3060
AAGAAGCCCA GCATGGCCAT CAGTGAGGAC TTCAGGGTAG ACTTTGTCCT GTAGCCTCCA 3120
CTTCTGCCCT AAGTTCCCCA GCATCCTGAC TACCTGTCTG CAGAGTTTGC CTTTGTTTTT 3180
TCCTGCAGGG AAGAAGGCCC ACCTTTGTGT CACTCACCTC CCCAGGCTCA GAGTCCCCAA 3240
GGCCCTGGGG TTCCAACTCA CTGTGCGTCT CCTCCACACA GACCAGTAGG TTCTCCTATG 3300
CTGACTCCAG GTTGCTTCAT ACAAGGAGGG TGGTTGAACT TCACACACGT AAGGTCTTAG 3360
TGCTTAACAG TTTAAAGGAA AGTCCTTGTT GAGGCACAAC TAAGTTTACA GGGAAAGGTA 3420
CACACATTCT CTCTCTCTCT CTCTCTCTGT CTATCTAGTT CCCCAGCTTG GAGAGCCTTT 3480
CCCCTTGCTT CTTTCTGAGG CCATATAAGC TTATAAGAAA AGTCCCAAAC CAAGAATAGG 3540
TCCTTGGCCA CAAGCAGGGT CTGATCCCCC ATCAGAGCTA TCTGAGCCTG CCTGTCTGGG 3600
CACCTGCTGC AACCATGCAG CTACCCTGCC AGGGGCACTC AGCAAACAGA ACCACAGGGC 3660
CCAGGAGGCA TTCCACACAG GCACTGCCCC AGGACAACAC AACAAGGACA GTCACAACAA 3720
GGACAACAAG GACACAACAC AACACACAAC AAGGACAGTC ACAACAAGCC TAGAGCCAGA 3780
AAGCAGATGG AAATGCTAAT GAGGTCAAAC GTAGGCTTCA TGGTGGGTGG AGTGGGGGTG 3840
GCTGGGCTCC CCCAGGACAG AGGGGACCCT GAGGTTGGCA AGGCTCTCAC CACTCAGCCT 3900
TATGGTCCCT TATCTCCTAT CTTCCCTCTT GAGAAAATAC ACGCTTTCTG CATGTATTAG 3960
AAACGCACGA GCTCCACCAA GTCTACAATG AAAGTTTGAA ATTTAACTGC AAGGAATTAG 4020
AAGCATATTT GCAATCATTG CAGCTTCTTC TTTCTTCTGC TCATAAAAGG AGGAACACTT 4080
TAGATAGAGG GCAAATATAT CTGAAAACCT AATTTCTTTC TTTTTTTGAT AAGGAAATCT 4140
TTTCCATCTC CATCCTAACA TGCACAACCT GTGARGAGAA TTGTTTCTAT AGTAACTGGT 4200
CTGTGATCTT TTGTGGCCAA GAGAATAGCA GGCAAGAATT AGGGCCTTGA CAGAATTTCC 4260
ACGAAGCTCT GAGAACATGT TTGTTTCGAA TGTCTGATTC CTCTTTGTCA TCAATGTGTA 4320
TGCTCTGTCC CCATCCTTCA CTCCTCCTCA AGCTCACACC AATTGGTTTG GCACAGGCAC 4380 AGAGCTGGTC CCTAGTTAAG TGGCATTTAT GTTAAAAAAA A
Seq ID NO: 76 Protein sequence Protein Accession ft: NP 071414
11 21 31 41 51 I
MLPGRLCWVP I I
LLLALGVGSG SGGGGDSRQR RLLAAKVNKH KPWIETSYHG VITENNDTVI 60 LDPPLVALDK DAPVPFAGEI CAFKIHGQEL PFEAWLNKT SGEGRLRAKS PIDCELQKEY 120 TFIIQAYDCG AGPHETAWKK SHKAWHIQV KDVNEFAPTF KEPAYKAWT EGKIYDSI Q 180 VEAIDEDCSP QYSQICNYEI VTTDVPFAID RNGNIRNTEK LSYDKQHQYE ILVTAYDCGQ 240 KPAAQDTLVQ VDVKPVCKPG WQDWTKRIEY QPGSGSMPLF PSIHLETCDG AVSSLQIVTE 300 LQTNYIGKGC DRETYSEKSL QKLCGASSGI IDLLPSPSAA TNWTAGLLVD SSEMIFKFDG 360
RQGAKIPDGI VPKNLTDQFT ITMWMKHGPS PGVRAEKETI LCNSDKTEMN RHHYALYVHN 420
CRLVFLLRKD FDQADTFRPA EFHWKLDQIC DKEWHYYVIN VEFPWTLYM DGATYEPYLV 480
TNDWPIHPΞH IAMQLTVGAC WQGGEVTKPQ FAQFFHGSLA SLTIRPGKME SQKVISCLQA 540
5 CKEGLDINSL ESLGQGIKYH FNPSQSILVM EGDDIGNINR ALQKVSYINS RQFPTAGVRR 600
LKVSSKVQCF GEDVCISIPE VDAYVMVLQA IEPRITLRGT DHFWRPAAQF ESARGVTLFP 660
DIKIVSTFAK TEAPGDVKTT DPKSEVLEEM LHNLDFCDIL VIGGDLDPRQ ECLELNHSEL 720
HQRHLDATNS TAGYSIYGVG SMSRYEQVLH HIRYRNWRPA SLEARRFRIK CSELNGRYTS 780
NEFNLEVSIL HEDQVSDKEH VNHLIVQPPF LQSVHHPESR SSIQHSSWP SIATWIIIS 840 0 VCMLVFWAM GVYRVRIAHQ HFIQETEAAK ESEMDWDDSA LTITVNPMEK HEGPGHGEDE 900 TEGEEEEEAE EEMSSSSGSD DSEEEEEEEG MGRGRHGQNG ARQAQLEWDD STLPY
Seq ID NO: 77 DNA sequence
Nucleic Acid Acceεsion # : Eos sequence 5 Coding sequence: 482..3007
1 11 21 31 41 51
I I I I I I
AACTGAGCTA ACAAGAAATA CTAGAAAAGG AGGAAGGAGA ACATTGCTGC AGCTTGGATC 60 0 TACAACCTAA GAAAGCAAGA GTGATCAATC TCAGCTCTGT TAAACATCTT GTTTACTTAC 120
TGCATTCAGC AGCTTGCAAA TGGTTAACTA TATGCAAAAA AGTCAGCATA GCTGTGAAGT 180
ATGCCGTGAA TTTTAATTGA GGGAAAAAGG GACAATTGCT TCAGGATGCT CTAGTATGCA 240
CTCTGCTTGA AATATTTTCA ATGAAATGCT CAGTATTCTA TCTTTGACCA GAGGTTTTAA 300
CTTTATGAAG CTATGGGACT TGACAAAAAG TGATATTTGA GAAGAAAGTA CGCAGTGGTT 360 5 GGTGTTTTCT TTTTTTTAAT AAAGGAATTG AATTACTTTG AACACCTCTT CCAGCTGTGC 420
ATTACAGATA ACGTCAGGAA GAGTCTCTGC TTTACAGAAT CGGATTTCAT CACATGACAA 480
CATGAAGCTG TGGATTCATC TCTTTTATTC ATCTCTCCTT GCCTGTATAT CTTTACACTC 540
CCAAACTCCA GTGCTCTCAT CCAGAGGCTC TTGTGATTCT CTTTGCAATT GTGAGGAAAA 600
AGATGGCACA ATGCTAATAA ATTGTGAAGC AAAAGGTATC AAGATGGTAT CTGAAATAAG 660 0 TGTGCCACCA TCACGACCTT TCCAACTAAG CTTATTAAAT AACGGCTTGA CGATGCTTCA 720
CACAAATGAC TTTTCTGGGC TTACCAATGC TATTTCAATA CACCTTGGAT TTAACAATAT 780
TGCAGATATT GAGATAGGTG CATTTAATGG CCTTGGCCTC CTGAAACAAC TTCATATCAA 840
TCACAATTCT TTAGAAATTC TTAAAGAGGA TACTTTCCAT GGACTGGAAA ACCTGGAATT 900
CCTGCAAGCA GATAACAATT TTATCACAGT GATTGAACCA AGTGCCTTTA GCAAGCTCAA 960 5 CAGACTCAAA GTGTTAATTT TAAATGACAA TGCTATTGAG AGTCTTCCTC CAAACATCTT 1020
CCGATTTGTT CCTTTAACCC ATCTAGATCT TCGTGGAAAT CAATTACAAA CATTGCCTTA 1080
TGTTGGTTTT CTCGAACACA TTGGCCGAAT ATTGGATCTT CAGTTGGAGG ACAACAAATG 1140
GGCCTGCAAT TGTGACTTAT TGCAGTTAAA AACTTGGTTG GAGAACATGC CTCCACAGTC 1200
TATAATTGGT GATGTTGTCT GCAACAGCCC TCCATTTTTT AAAGGAAGTA TACTCAGTAG 1260 0 ACTAAAGAAG GAATCTATTT GCCCTACTCC ACCAGTGTAT GAAGAACATG AGGATCCTTC 1320
AGβATCATTA CATCTGGCAG CAACATCTTC AATAAATGAT AGTCGCATGT CAACTAAGAC 1380
CACGTCCATT CTAAAACTAC CCACCAAAGC ACCAGGTTTG ATACCTTATA TTACAAAGCC 1440
ATCCACTCAA CTTCCAGGAC CTTACTGCCC TATTCCTTGT AACTGCAAAG TCCTATCCCC 1500
ATCAGGACTT CTAATACATT GTCAGGAGCG CAACATTGAA AGCTTATCAG ATCTGAGACC 1560 5 TCCTCCGCAA AATCCTAGAA AGCTCATTCT AGCGGGAAAT ATTATTCACA GTTTAATGAA 1620
GTCTGATCTA GTGGAATATT TCACTTTGGA AATGCTTCAC TTGGGAAACA ATCGTATTGA 1680
AGTTCTTGAA GAAGGATCGT TTATGAACCT AACGAGATTA CAAAAACTCT ATCTAAATGG 1740
TAACCACCTG ACCAAATTAA GTAAAGGCAT GTTCCTTGGT CTCCATAATC TTGAATACTT 1800
ATATCTTGAA TACAATGCCA TTAAGGAAAT ACTGCCAGGA ACCTTTAATC CAATGCCTAA 1860 0 ACTTAAAGTC CTGTATTTAA ATAACAACCT CCTCCAAGTT TTACCACCAC ATATTTTTTC 1920
AGGGGTTCCT CTAACTAAGG TAAATCTTAA AACAAACCAG TTTACCCATC TACCTGTAAG 1980
TAATATTTTG GATGATCTTG ATTTACTAAC CCAGATTGAC CTTGAGGATA ACCCCTGGGA 2040
CTGCTCCTGT GACCTGGTTG GACTGCAGCA ATGGATACAA AAGTTAAGCA AGAACACAGT 2100
GACAGATGAC ATCCTCTGCA CTTCCCCCGG GCATCTCGAC AAAAAGGAAT TGAAAGCCCT 2160 5 AAATAGTGAA ATTCTCTGTC CAGGTTTAGT AAATAACCCA TCCATGCCAA CACAGACTAG 2220
TTACCTTATG GTCACCACTC CTGCAACAAC AACAAATACG GCTGATACTA TTTTACGATC 2280
TCTTACGGAC GCTGTGCCAC TGTCTGTTCT AATATTGGGA CTTCTGATTA TGTTCATCAC 2340
TATTGTTTTC TGTGCTGCAG GGATAGTGGT TCTTGTTCTT CACCGCAGGA GAAGATACAA 2400
AAAGAAACAA GTAGATGAGC AAATGAGAGA CAACAGTCCT GTGCATCTTC AGTACAGCAT 2460 0 GTATGGCCAT AAAACCACTC ATCACACTAC TGAAAGACCC TCTGCCTCAC TCTATGAACA 2520
GCACATGGTG AGCCCCATGG TTCATGTCTA TAGAAGTCCA TCCTTTGGTC CAAAGCATCT 2580
GGAAGAGGAA GAAGAGAGGA ATGAGAAAGA AGGAAGTGAT GCAAAACATC TCCAAAGAAG 2640
TCTTTTGGAA CAGGAAAATC ATTCACCACT CACAGGGTCA AATATGAAAT ACAAAACCAC 2700
GAACCAATCA ACAGAATTTT TATCCTTCCA AGATGCCAGC TCATTGTACA GAAACATTTT 2760 5 AGAAAAAGAA AGGGAACTTC AGCAACTGGG AATCACAGAA TACCTAAGGA AAAACATTGC 2820
TCAGCTCCAG CCTGATATGG AGGCACATTA TCCTGGAGCC CACGAAGAGC TGAAGTTAAT 2880
GGAAACATTA ATGTACTCAC GTCCAAGGAA GGTATTAGTG GAACAGACAA AAAATGAGTA 2940
TTTTGAACTT AAAGCTAATT TACATGCTGA ACCTGACTAT TTAGAAGTCC TGGAGCAGCA 3000
AACATAGATG GAGAGTTTGA GGGCTTTCGC AGAAATGCTG TGATTCTGTT TTAAGTCCAT 3060 0 ACCTTGTAAA TAAGTGCCTT ACGTGAGTGT GTCATCAATC AGAACCTAAG CACAGCAGTA 3120
AACTATGGGG AAAAAAAAAG AAGAAGAAAA GAAACTCAGG GATCACTGGG AGAAGCCATG 3180
GCATTATCTT CAGGCAATTT AGTCTGTCCC AAATAAAATC AATCCTTGCA TGTAAATC
Seq ID NO: 78 Protein sequence I Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MKLWIHLFYS SLLACISLHS QTPVLSSRGS CDSLCNCEEK DGTMLINCEA KGIKMVSEIS 60 0 VPPSRPFQLS LLNNGLTMLH TNDFSGLTNA ISIHLGFNNI ADIEIGAFNG LGLLKQLHIN 120
HNSLEILKED TFHGLENLEF LQADNNFITV IEPSAFSKLN RLKVLILNDN AIESLPPNIF 180
RFVPLTHLDL RGNQLQTLPY VGFLEHIGRI LDLQLEDNKW ACNCDLLQLK TWLENMPPQS 240
IIGDWCNSP PFFKGSILSR LKKESICPTP PVYEEHEDPS GSLHLAATSS INDSRMSTKT 300
TSILKLPTKA PGLIPYITKP STQLPGPYCP IPCNCKVLSP SGLLIHCQER NIESLSDLRP 360 PPQNPRKLIL AG IIHSLMK SDLVEYFTLE MLHLGNNRIE VLEEGSFMNL TRLQKLYLNG 420 NHLTKLSKGM FLGLHNLEYL YLEYNAIKEI LPGTFNPMPK LKVLYLNNNL LQVLPPHIFS 480 GVPLTKVNLK TNQFTHLPVS NI DDLDLLT QIDLEDNPWD CSCDLVGLQQ WIQKLSKNTV 540 TDDILCTSPG HLDKKELKAL NSEILCPGLV NNPSMPTQTS YLMVTTPATT TNTADTILRS 600 LTDAVPLSVL ILGLLIMFIT IVFCAAGIW LVLHRRRRYK KKQVDEQMRD NSPVHLQYSM 660 YGHKTTHHTT ERPSASLYEQ HMVSPMVHVY RSPSFGPKHL EEEEERNEKE GSDAKHLQRS 720 LLEQENHSPL TGSNMKYKTT NQSTEFLSFQ DASSLYRNIL EKERELQQLG ITEYLRKNIA 780 QLQPDMEAHY PGAHEELKLM ETLMYSRPRK VLVEQTKNEY FELKANLHAE PDYLEVLEQQ 840 T
Seq ID NO: 79 DNA sequence
Nucleic Acid Accession ft: NM_016640.2
Coding sequence: 39..1358
11 21 31
GCTTAAGTTG ACCTCTGGGT CCGGAATCGC GGGCAAAGAT GGCGGCGGCG AGGTGTTGGA 60
GGCCTTTGCT ACGCGGTCCG AGGCTTTCAT TGCACACCGC GGCTAATGCC GCCGCCACGG 120
CTACAGAAAC GACCTCCCAA GACGTCGCGG CGACCCCCGT CGCGCGGTAC CCGCCGATTG 180
TGGCCTCCAT GACAGCCGAC AGCAAAGCTG CACGGCTGCG GCGGATCGAG CGCTGGCAGG 240
CGACGGTGCA CGCTGCGGAG TCGGTAGACG AGAAGCTGCG AATCCTCACC AAGATGCAGT 300
TTATGAAGTA CATGGTTTAC CCGCAGACCT TCGCGCTGAA TGCCGACCGC TGGTACCAGT 360
ACTTCACCAA GACCGTGTTC CTGTCGGGTC TGCCGCCGCC CCCAGCGGAG CCCGAGCCCG 420
AGCCCGAACC CGAACCTGAA CCTGCGCTGG ACCTCGCGGC GCTGCGTGCG GTCGCCTGCG 480
ACTGCCTGCT GCAGGAGCAC TTCTACCTGC GGCGCAGGCG GCGCGTGCAC CGTTACGAGG 540
AGAGCGAGGT CATATCTTTG CCCTTCCTGG ATCAGCTGGT GTCAACCCTC GTGGGCCTCC 600
TCAGCCCACA CAACCCGGCC CTGGCCGCTG CCGCCCTCGA TTATAGATGC CCAGTTCATT 660
TTTACTGGGT GCGTGGTGAA GAAATTATTC CTCGTGGTCA TCGAAGAGGT CGAATTGATG 720
ACTTGCGATA CCAGATAGAT GATAAACCAA ACAACCAGAT TCGAATATCC AAGCAACTCG 780
CAGAGTTTGT GCCATTGGAT TATTCTGTTC CTATAGAAAT CCCCACTATA AAATGTAAAC 840
CAGACAAACT TCCATTATTC AAACGGCAGT ATGAAAACCA CATATTTGTT GGCTCAAAAA 900
CTGCAGATCC TTGCTGTTAC GGTCACACCC AGTTTCATCT GTTACCTGAC AAATTAAGAA 960
GGGAAAGGCT TTTGAGACAA AACTGTGCTG ATCAGATAGA AGTTGTTTTT AGAGCTAATG 1020
CTATTGCAAG CCTTTTTGCT TGGACTGGAG CACAAGCTAT GTATCAAGGA TTCTGGAGTG 1080
AAGCAGATGT TACTCGACCT TTTGTCTCCC AGGCTGTGAT CACAGATGGA AAATACTTTT 1140
CCTTTTTCTG CTACCAGCTA AATACTTTGG CACTGACTAC ACAAGCTGAT CAAAATAACC 1200
CTCGTAAAAA TATATGTTGG GGTACACAAA GTAAGCCTCT TTATGAAACA ATTGAGGATA 1260
ATGATGTGAA AGGTTTTAAT GATGATGTTC TACTTCAGAT AGTTCACTTT CTACTGAATA 1320
GACCAAAAGA AGAAAAATCA CAGCTGTTGG AAAACTGAAA AAGCATATTT GATTGAGAAC 1380
TGTGGGAATA TTTAAATTTT ACTGAAGGAA CAATAATGAT GAGATTTGTA ACTGTCAACT 1440
ATTAAATACA TTGATTTTTG AGACAAAAAA AAAAAAAAAA AA
Seq ID NO: 80 Protein sequence
Protein Accession ft: NP_057724.1
1 11 21 31 41 51
| 1 1 1 1 11 11 | 1 MAAARCWRPL LRGPRLSLHT AANAAATATE TTSQDVAATP VARYPPIVAS MTADSKAARL 60
RRIERWQATV HAAESVDEKL RILTKMQFMK YMVYPQTFAL NADRWYQYFT KTVFLSGLPP 120
PPAEPEPEPE PEPEPALDLA ALRAVACDCL LQEHFYLRRR RRVHRYEESE VISLPFLDQL 180
VSTLVGLLSP HNPALAAAAL DYRCPVHFYW VRGEEIIPRG HRRGRIDDLR YQIDDKPNNQ 240
IRISKQLAEF VPLDYSVPIE IPTIKCKPDK LPLFKRQYEN HIFVGSKTAD PCCYGHTQFH 300
LLPDKLRRER LLRQNCADQI EWFRANAIA SLFAWTGAQA MYQGFWSEAD VTRPFVSQAV 360
ITDGKYFSFF CYQLNTLALT TQADQNNPRK NICWGTQSKP LYETIEDNDV KGFNDDVLLQ 420
IVHFLLNRPK EEKSQLLEN
Seq ID NO: 81 DNA sequence
Nucleic Acid Accession ft: FGENESH predicted Coding sequence: 1..2070
11 21 31 41 51
I I I I i
ATGAGCGGTG CGGGGGTGGC GGCTGGGACG CGGCCCCCCA GCTCGCCGAC CCCGGGCTCT 60 CGGCGCCGGC GCCAGCGCCC CTCTGTGGGC GTCCAGTCCT ■ TGAGGCCGCA GAGCCCGCAG 120 CTCAGGCAGA GCGACCCGCA GAAACGGAAC CTGGACCTGG AGAAAAGCCT GCAGTTCCTG 180 CAGCAGCAGC ACTCGGAGAT GCTGGCCAAG CTCCATGAGG AGATCGAGCA TCTGAAGCGG 240 GAAAACAAGG GTGAGCCGGC GCGGGGCCCT AGGCCGGCCC TGCCTCCCCA GGCACACTCA 300 ACACTGCCGC TCCCGCAGCA CAGAAACACA GCCATCAACT CCAGCACACG CCTGGGCTCA 360 GGGGGAACAC AGGACGGGGA GCCCCTCCAG ACTGTCCTTG CCCACCTGGC TGCACTGGCC 420 CCTGTATGCC AACCCAGTGG GTACAGGTTC TGGGGGACCT GGACAGATGC CGCTACCTCT 480 AGCCGTGGCT GGACGATGTT ATGCAGCCAA GCACAGCACG TGCTGCTCTC GGGAAGCCCA 540 GGGCCTGAGG TCATTGCAGG GCGGCAGGTG GCCACAGGGT GCTCCCCAGA CCTCCCTCCT 600 CCAAGTAGAG CTGAAATGGG AAGGAACCCC TGGGACAGCC CCTGCCCTGC TAGATCTTTG 660 CCTCAGATTG CTGCTGTGGC CAGGCCCAGG ATTTCCAGCC CTATGGCTCT GAGTCCTCAC 720 ATGCTGGGGG CCCAGGGGAT ATGGACACAC TCCATCCAGG GATCCCTTCC TGCCATCTGG 780 GCAGCAACCA TGGGGACAAA GGGAGGAAGC AGAGTCCTGT TTCCTTGCCA CTTGTCCAAβ 840 GCACTTCCCC ATCCTGACAG CGGCCCCCAC CCAGCCCAGG ATCCTGGGCT GTGGTCTCAA 900 GCTCACTTCC CATTATCTTT GGGGCTGGGG CTGACATCAG GAGGACATCT GACTGGTGGA 960 TGGAGCCAGC CTGGGAACAT CGCAGCTGGG GCAGTGCCTA GGGCTCTCCC TTCCCAGGGA 1020 GACATGGAGA AGGGGGTTGA GGGAGGGCCC TTCCCTAGCC GCTGTGGCAA CTCCAGTGAG 1080 CTGTTCTGGG CAAAGTGTGG CCCAAGTCGG CAGCCCCAGC CCTGCAGTGC TGGGGACGCT 1140 GACAGGACAC GGGAAGAGGC CATGCTTTCC CTCGGGACCT GCTGTTCCAT GTGTCCCAAG 1200 CCCTCCTGCT TTCCAGATGG CCCCTCAGGA AACCACCTTT CCAGGGCCTC TGCTCCCTTG 1260 GGCGCTCGCT GGGTCTGCAT CAACGGAGTG TGGGTAGAGC CGGGAGGACC CAGCCCTGCC 1320 AGGCTGAAGG AGGGCTCCTC ACGGACACAC AGGCCAGGAG GCAAGCGTGG GCGTCTTGCG 1380 GGCGGTAGCG CCGACACTGT GCGCTCTCCT GCAGACAGCC TCTCCATGTC AAGCTTCCAG 1440 TCTGTCAAGT CCATCTCTAA TTCAGCCAAC TCTCAAGGCA AGGCCAGGCC CCAGCCCGGC 1500 TCCTTCAACA AGCAAGATTC AAAAGCTGAC GTCTCCCAGA AGGCGGACCT GGAAGAGGAG 1560 CCCCTACTTC ACAACAGCAA GCTGGACAAA GTTCCTGGGG TACAAGGGCA GGCCAGAAAG 1620 GAGAAAGCAG AGGCCTCTAA TGCAGGAGCT GCCTGTATGG GGAACAGCCA GCACCAGGGC 1680 AGGCAGATGG GGGCGGGGGC ACACCCCCCA ATGATCCTGC CCCTTCCCCT GCGAAAGCCC 1740 ACCACACTTA GGCAGTGCGA AGTGCTCATC CGCGAGCTGT GGAATACCAA CCTCCTGCAG 1800 ACCCAAGAGC TGCGGCACCT CAAGTCCCTC CTGGAAGGGA GCCAGAGGCC CCAGGCAGCC 1860 CCGGAGGAAG CTAGCTTTCC CAGGGACCAA GAAGCCACGC ATTTCCCCAA GGTCTCCACC 1920 AAGAGCCTCT CCAAGAAATG CCTGAGCCCA CCTGTGGCGG AGCGTGCCAT CCTGCCCGCA 1980 CTGAAGCAGA CCCCGAAGAA CAACTTTGCC GAGAGGCAGA AGAGGCTGCA GGCAATGCAG 2040 AAACGGCGCC TGCATCGCTC AGTGCTTTGA
Seq ID NO 82 Protem sequence Protem Accession # FGENESH predicted
11 21 31 41 51
I I I I I
MSGAGVAAGT RPPSSPTPGS RRRRQRPSVG VQSLRPQSPQ LRQSDPQKRN LDLEKSLQFL 60 QQQHSEMLAK LHEEIEHLKR ENKGEPARGP RPALPPQAHS TLPLPQHRNT AINSSTRLGS 120 GGTQDGEPLQ TVLAHLAALA PVCQPSGYRF WGTWTDAATS SRGWTMLCSQ AQHVLLSGSP 180 GPEVIAGRQV ATGCSPDLPP PSRAEMGRNP WDSPCPARSL PQIAAVARPR ISSPMALSPH 240 MLGAQGIWTH SIQGSLPAIW AATMGTKGGS RVLFPCHLSK ALPHPDSGPH PAQDPGLWSQ 300 AHFPLSLGLG LTSGGHLTGG WSQPGNIAAG AVPRALPSQG DMEKGVEGGP FPSRCGNSSE 360 LFWAKCGPSR QPQPCSAGDA DRTREEAMLS LGTCCSMCPK PSCFPDGPSG NHLΞRASAPL 420 GARWVCINGV WVEPGGPSPA RLKEGSSRTH RPGGKRGRLA GGSADTVRSP ADSLSMSSFQ 480 SVKSISNSAN SQGKARPQPG SFNKQDSKAD VSQKADLEEE PLLHNSKLDK VPGVQGQARK 540 EKAEASNAGA ACMGNSQHQG RQMGAGAHPP MILPLPLRKP TTLRQCEVLI RELWNTNLLQ 600 TQELRHLKSL LEGSQRPQAA PEEASFPRDQ EATHFPKVST KSLSKKCLSP PVAERAILPA 660 LKQTPKNNFA ERQKRLQAMQ KRRLHRSVL
Seq ID NO 83 DNA sequence
Nucleic Acid Accession ft NM_005264 1
Coding sequence 557 1954
1 11 21 31 41 l l l l l
GAATTCCGGC CAGAAGAAAT CTGGCCTCGG AACACGCCAT TCTCCGCGCC GCTTCCAATA 60 ACCACTAACA TCCCTAACGA GCATCCGAGC CGAGGGCTCT GCTCGGAAAT CGTCCTGGCC 120 CAACTCGGCC CTTCGAGCTC TCGAAGATTA CCGCATCTAT TTTTTTTTTC TTTTTTTTCT 180 TTTCCTAGCG CAGATAAAGT GAGCCCGGAA AGGGAAGGAG GGGGCGGGGA CACCATTGCC 240 CTGAAAGAAT AAATAAGTAA ATAAACAAAC TGGCTCCTCG CCGCAGCTGG ACGCGGTCGG 300 TTGAGTCCAG GTTGGGTCGG ACCTGAACCC CTAAAAGCGG AACCGCCTCC CGCCCTCGCC 360 ATCCCGGAGC TGAGTCGCCG GCGGCGGTGG CTGCTGCCAG ACCCGGAGTT TCCTCTTTCA 420 CTGGATGGAG CTGAACTTTG GGCGGCCAGA GCAGCACAGC TGTCCGGGGA TCGCTGCACG 480 CTGAGCTCCC TCGGCAAGAC CCAGCGGCGG CTCGGGATTT TTTTGGGGGG GCGGGGACCA 540 GCCCCGCGCC GGCACCATGT TCCTGGCGAC CCTGTACTTC GCGCTGCCGC TCTTGGACTT 600 GCTCCTGTCG GCCGAAGTGA GCGGCGGAGA CCGCCTGGAT TGCGTGAAAG CCAGTGATCA 660 GTGCCTGAAG GAGCAGAGCT GCAGCACCAA GTACCGCACG CTAAGGCAGT GCGTGGCGGG 1 720 CAAGGAGACC AACTTCAGCC TGGCATCCGG CCTGGAGGCC AAGGATGAGT GCCGCAGCGC 780 CATGGAGGCC CTGAAGCAGA AGTCGCTCTA CAACTGCCGC TGCAAGCGGG GTATGAAGAA 840 GGAGAAGAAC TGCCTGCGCA TTTACTGGAG CATGTACCAG AGCCTGCAGG GAAATGATCT 900 GCTGGAGGAT TCCCCATATG AACCAGTTAA CAGCAGATTG TCAGATATAT TCCGGGTGGT 960 CCCATTCATA TCAGATGTTT TTCAGCAAGT GGAGCACATT CCCAAAGGGA ACAACTGCCT 1020 GGATGCAGCG AAGGCCTGCA ACCTCGACGA CATTTGCAAG AAGTACAGGT CGGCGTACAT 1080 CACCCCGTGC ACCACCAGCG TGTCCAACGA TGTCTGCAAC CGCCGCAAGT GCCACAAGGC 1140 CCTCCGGCAG TTCTTTGACA AGGTCCCGGC CAAGCACAGC TACGGAATGC TCTTCTGCTC 1200 CTGCCGGGAC ATCGCCTGCA CAGAGCGGAG GCGACAGACC ATCGTGCCTG TGTGCTCCTA 1260 TGAAGAGAGG GAGAAGCCCA ACTGTTTGAA TTTGCAGGAC TCCTGCAAGA CGAATTACAT 1320 CTGCAGATCT CGCCTTGCGG ATTTTTTTAC CAACTGCCAG CCAGAGTCAA GGTCTGTCAG 1380 CAGCTGTCTA AAGGAAAACT ACGCTGACTG CCTCCTCGCC TACTCGGGGC TTATTGGCAC 1440 AGTCATGACC CCCAACTACA TAGACTCCAG TAGCCTCAGT GTGGCCCCAT GGTGTGACTG 1500 CAGCAACAGT GGGAACGACC TAGAAGAGTG CTTGAAATTT TTGAATTTCT TCAAGGACAA 1560 TACATGTCTT AAAAATGCAA TTCAAGCCTT TGGCAATGGC TCCGATGTGA CCGTGTGGCA 1620 GCCAGCCTTC CCAGTACAGA CCACCACTGC CACTACCACC ACTGCCCTCC GGGTTAAGAA 1680 CAAGCCCCTG GGGCCAGCAG GGTCTGAGAA TGAAATTCCC ACTCATGTTT TGCCACCGTG 1740 TGCAAATTTA CAGGCACAGA AGCTGAAATC CAATGTGTCG GGCAATACAC ACCTCTGTAT 1800 TTCCAATGGT AATTATGAAA AAGAAGGTCT CGGTGCTTCC AGCCACATAA CCACAAAATC 1860 AATGGCTGCT CCTCCAAGCT GTGGTCTGAG CCCACTGCTG GTCCTGGTGG TAACCGCTCT 1920 GTCCACCCTA TTATCTTTAA CAGAAACATC ATAGCTGCAT TAAAAAAATA CAATATGGAC 1980 ATGTAAAAAG ACAAAAACCA AGTTATCTGT TTCCTGTTCT CTTGTATAGC TGAAATTCCA 2040 GTTTAGGAGC TCAGTTGAGA AACAGTTCCA TTCAACTGGA ACATTTTTTT TTTTCCTTTT 2100 AAGAAAGCTT CTTGTGATCC TTCGGGGCTT CTGTGAAAAA CCTGATGCAG TGCTCCATCC 2160 AAACTCAGAA GGCTTTGGGA TATGCTGTAT TTTAAAGGGA CAGTTTGTAA CTTGGGCTGT 2220 AAAGCAAACT GGGGCTGTGT TTTCGATGAT GATGATCATC ATGATCATGA , TGATTTTAAC 2280 AGTTTTACTT CTGGCCTTTC CTAGCTAGAG AAGGAGTTAA TATTTCTAAG GTAACTCCCA 2340 TATCTCCTTT AATGACATTG ATTTCTAATG ATATAAATTT CAGCCTACAT TGATGCCAAG 2400 CTTTTTTGCC ACAAAGAAGA TTCTTACCAA GAGTGGGCTT TGTGGAAACA . GCTGGTACTG 2460 ATGTTCACCT TTATATATGT ACTAGCATTT TCCACGCTGA TGTTTATGTA . CTGTAAACAG 2520 TTCTGCACTC TTGTACAAAA GAAAAAACCA CCCGGAATTC
Seq ID NO 84 Protem sequence Protein Accession # NM 005264 1 1 11 21 31 41 51
I I I I I I
MFLATLYFAL PLLDLLLSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 60
SLASGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWΞMYQSL QGNDLLEDSP 120
YEPVNSRLSD IFRWPFISD VFQQVEHIPK GNNCLDAAKA CNLDDICKKY RSAYITPCTT 180
SVSNDVCNRR KCHKALRQFF DKVPAKHSYG MLFCSCRDIA CTERRRQTIV PVCSYEEREK 240
PNCLNLQDSC KTNYICRSRL ADFFTNCQPE SRSVSSCLKE NYADCLLAYS GLIGTVMTPN 300
YIDSSSLSVA PWCDCSNSGN DLEECLKFLN FFKDNTCLKN AIQAFGNGSD VTVWQPAFPV 360
QTTTATTTTA LRVKNKPLGP AGSENEIPTH VLPPCANLQA QKLKΞNVSGN THLCISNGNY 420 EKEGLGASSH ITTKSMAAPP SCGLSPLLVL WTALSTLLΞ LTETS
Seq ID NO: 85 DNA sequence Nucleic Acid Accession ft: XM.027172. Coding sequence: 143..1405
1 11 21 31 41 51
I I I I I I
GGTGGAGACA CCGCCTCAGG GCTCGGTGCA CAGTGGACAT TTGGGGAGCG TTGTGGGTGA 60
CCCCCACACA GGCACTGGGA ATGCAGGGGA GAGGGGGCCA AGGGGGAAAG GGGCCAGAGT 120
GTTGGCTTTG GATTCAGGAG GGATGGATTC CAGTCCTAGC TTGCCACTTA TTAGGACTCC 180
TGAGAGCAGC CTCCATGAGG CCCTGGACCA GTGCATGACC GCCCTGGACC TCTTCCTCAC 240
CAACCAGTTC TCAGAAGCAC TCAGCTACCT CAAGCCCAGA ACCAAGGAAA GCATGTACCA 300
CTCACTGACA TATGCCACCA TCCTGGAGAT GCAGGCCATG ATGACCTTTG ACCCTCAβGA 360
CATCCTGCTT GCCGGCAACA TGATGAAGGA GGCACAGATG CTGTGTCAGA GGCACCGGAG 420
GAAGTCTTCT GTAACAGATT CCTTCAGCAG CCTGGTGAAC CGCCCCACGC TGGGCCAATT 480
CACTGAAGAG GAAATCCACG CTGAGGTCTG CTATGCAGAG TGCCTGCTGC AGCGAGCAGC 540
CCTGACCTTC CTGCAGGGTT CCTCACACGG AGGGGCAGTC AGGCCCAGAG CCTTGCATGA 600
TCCCTCTCAC GCCTGCAGCT GCCCACCTGG GCCAGGCCGT CAGCATCTTT TCCTCCTGCA 660
GGACGAGAAC ATGGTGAGCT TCATCAAAGG CGGCATCAAA GTTCGAAACA GCTACCAGAC 720
CTACAAGGAG CTGGACAGCC TTGTTCAGTC CTCACAATAC TGCAAGGGTG AGAACCACCC 780
GCACTTTGAA GGAGGAGTGA AGCTTGGTGT AGGGGCCTTC AACCTGACAC TGTCCATGCT 840
TCCTACTAGG ATCCTGAGGC TGTTGGAGTT TGTGGGGTTT TCAGGAAACA AGGACTATGG 900
GCTGCTGCAG CTGGAGGAGG GAGCGTCAGG GCACAGCTTC CGCTCTGTGC TCTGTGTCAT 960
GCTCCTGCTG TGCTACCACA CCTTCCTCAC CTTCGTGCTC GGTACTGGGA ACGTCAACAT 1020
CGAGGAβGCC GAGAAGCTCT TGAAGCCCTA CCTGAACCGG TACCCTAAGG GTGCCATCTT 1080
CCTGTTCTTT GCAGGGAGGA TTGAAGTCAT TAAAGGCAAC ATTGATGCAG TGAGTGATGG 1140
GGGTCCGGGC CGGGGCTGGG GATCCCTCGG GGTCTCCCAG ACCAGCAGGA AGTCAGGCAC 1200
ATGTGACATA CTCAGGGACA GGATAGACTG GGGGCGGGGG GGGGGCCAAG AGAGAACCAA 1260
CCAGAGAGCA GGGGCAGGAG AGGCCCTTCT GGCAGAGCAG CCTGGGAAGA CAAGGGAGGA 1320
GGAGβCATTT GTGGTGCCTG GGATTTTGAC TGGGAGATAT AGGACTGCAG CATTGCAGTG 1380
GAGGGAGGTG GAGGGAGGTG CTTGAGGGAG GCAGAGGTTA GGAAAGCCCA TCTGTTTAGG 1440
GCATGACGAT TAGGCTGGAG TCTGGTACCT CCCCTCCATT ATAGCTCTCT CCTGCTCTTT 1500
CATTTTGTTA CTAAAAACCA GAGTCCTAGG CGGGGGCTGT ATTTGAGCCC AACGTCATGT 1560
AAGACTTAGG AGGTAAAACC AGGACTGGAG GCCAGATCTC CTGGCTCCTG GGGCCCCACC 1620
TGAGCCTAGC ACAGGGCTGβ ACCACTATGC CCTGGAGGAG TCCCGGTCTG CTGTGGTGTT 1680
GGGAGGTTCG GAGGATGCAG AGGGGTTGGG GCTGGGTGGG CACCCGTCAG GCTGACCAGA 1740
AGGTGCCTGC AGGCCATCCG GCGTTTCGAG GAGTGCTGTG AGGCCCAGCA GCACTGGAAG 1800
CAGTTCCACC ACATGTGCTA CTGGGAGCTG ATGTGGTGCT TCACCTACAA GGGCCAGTGG 1860
AAGATGTCCT ACTTCTACGC CGACCTGCTC AGCAAGGAGA ACTGCTGGTC CAAGGTGGGC 1920
TGATGCCACG TGTTAGGGGC ATTGGGTGAC CAGβGCTGAC TGTGTGCCTC CAGACCACGG 1980
GCCAAATCCC TAACTGAACA CAGATGTCTC AGCTGGAATC TAAACATAAC CTTAAATTCT 2040
AATAGGACTC AGGCTTGGAA GGAACTAAAG ACCACAAGAG AAACTTCTGA ACCACAATGT 2100
GTCACAAAGA GATTTCTAGT CACAAAGGAC AGAAACATGG CTCCCTCTGT CCAGTAGAAC 2160
TGTTTCTGTG GTAGAAATGT TCTACTTATG CACTGCCCAA ATATGGTAGT CACCAGCCAC 2220
ATGTGCACAA TGAGCACATG AAATGTGCCT AGTGCAACTG GGAAACTGAT TGTTTTCAGT 2280
TTTATTTAAT TTTAATTAAC TAAATGTTAA ATTTAAATAG CCATGTAGGG CTTGTGGCCA 2340
CTATATTGGA CTATGCAGGT CCAAAACACA AAAGGCTCAT ATAACTGAAC ATTCTTGGCA 2400
CATCCGACTT CAGGTAGGGC TGGATCCAGG AATTCAAATG ATGTCGTCTG GCTTGGTCTT 2460
TCCATTTGTG GCTGTGCTCT CTCCTATGAC ATCTTTGTTT CTGCTGCATC TTTGCAGGAA 2520
GGTTCTCTCC ATGTGACAGG CAAGGTGGCC ACGGGCTGCT TCTACTCATA TCCTCCCCTT 2580
GGTTTCAACC .AGAGTCCCAC AGTTTGAGCC TCACTGGTCT GACTTGTCAC CTGCCAATGC 2640
CTGGAACAGA GGGGTGGGAA GATTCCTCAT GGGCTGAGAG TAGGAGAGGG GTGGTTCCAC 2700
AGAAGAAAAT GATGCACCCA GAAATAGTGG AGGGATTAAC AAGATGCCAT ACAGGCAAAA 2760
CAAAGCCAAA CAGATGCCCG CCTACCAAAG ATGAAATTTA TCATGGTAAG TATTGAAATA 2820
AGTGTTAGCT TGTACCATCA TAGTAATGAT AGTGCAGAAA TTGGAACCAA GAGTCTTACA 2880
ACCACCTAGC TCAGCAAACG TCTAATCTGT TATTTGTAAA TACACAGGAC ATGTGTCTTC 2940
ATGGCTTCAT CCCCTGCCCA TAGCAGACAT TGCTAATCAA TCCTCTGCCA TGAGCCTAGC 3000
TGTGACCTTA GATACCTTCC CTGCAAAGCT CCAGGCAGCC GTTAGAACTG ACCCACATTG 3060
GCACCTGTTA GGAGACCTGT CATCTGCATC TGGTCCCTCC CCCTCCTCTG CATGGAGGTC 3120
TCTTCCGTAG CCCTGCCTGG GGACCAAGCT GAAGGGGAAT TCTCTGGGTC TGGGGCAGGT 3180
GGGGCTGGGG AAGGGAGCAG GCTTCTACTG AGCTCTCAAC ATGTCTGGCA CCTGTCATGT 3240
CCTCCACACC ACACCCAGTG AGGAGAAGTT ATTATCTCCA TTGGGCACAT GAGGGCCACT 3300
GATGCTAAGC GAGGACTGTG ACTTTCCCAC CCACATGGCT GTTGGTGACA GACACCGGAT 3360
TTGAGGACAG TCCTGTGTGA CTCAGAGGCC TCTGCTTCTC TCTTGCTCCT AGAGTCCTCC 3420
TGAGGAGTCG GGGCTTGCCC TGAGCCCACC CTGCTGTTGA AGGTGCTTCC TCAGGCCCAG 3480
CTCCCATGGC CCCCACACCC CCTCCTCATC ACCTCCTACT CCCAAAAAGG ACAAAGCCTC 3540
AGGGAACCTT χTTT TTTTT TTAGAGACAG GGTCTTGCTA TGTTGGTCAG GCTAGTCTTG 3600
AACTCCTGGG CCCAAGCAAT CTTCCCACCT CTGCCTCCTA AAGTGCTGGG ATTCTGGGCC 3660
TTAGGGAACC TTTTTGAACT GAAAGTGACT CTCGAAGCCT TCCTGTAGAG TGAGGTGGGT 3720
GGCTGGGGCT AACCATATGG GGAAGGAGAG ACCTGGTGGG GGCACACAGC TGCTATATAG 3780
AGGAACAGAA GGTGGGCCAG GCCTCCCAGC TGTCAGGAAA TCTGGCTCAG TCCCCAGACC 3840
GCTGTGTGGC TTTGGGGTGG CCAGTCCCTC TCTCTCTGCA ACACTCTCCT CATGAGGACT 3900
TCTGTGAAAA ATGGGGGTTG TAACCCTCTG AGTTCTGGGG CCCCACCCAT TTCTAATCTC 3960 CAGAACTTGG CCACCACAGA CTCCACCAAC TTCTAGTCCT GGGGCCTGGG CCTCTGGCCA 4020 TTGCCATAGG CACCACCTGC TCTGTGCAGG CAGCGCCCCC CTCTGCCAGG ATCCTCCGAG 4080 GTCAGCTGCT GGGTCTGACC CGCAGACCCT GGCTGAGCGA CGGATGAACG GAGTATGCAG 4140 ACACAGGCTT GCCTGTCAGC AGATGGGGGA CCCCTGCCAG AGTCAGCAGC GGCCCCCATA 4200 AGCCTGCCAC GCTTGCATTT ATTTAGTACA GATGTAATGA CAAAGGCCTA AAGCAAACTC 4260 CATTTGTGGG TAATTAACAT TGTCGCCCCC CCAGAAAGAG CAGTCCTCCG CATGATGATT 4320 AAAGGCCAGG TTCCGAGGCC TAAGTAAACC AACTTATCTA GATCAATTCC CTTACTTCTT 4380 GTTATCTACT CTGAGAGAAT TCAGCTGCCT TCAGCCAAAT CCTTTCCCGA AGCTTTTGCA 4440 AAACCTCCGA GCCTTCCAAG GTTTGCTTCT TTCTGTAATT TTTCTCACCA CCCTGACCTA 4500 TCTCCTGCAG TCAGCCCTGT GGAGGCCTTT GTGTTTCCCC CAGTGCTGGC AGCCTAGAGG 4560 CTGAGATGGC CAGAAACAAG GTGGTGACAG TGGCGTGCTC AGGGCTTGGG AAACCCAAGG 4620 AGCTAAAGGC ATGCCCAGGC AACCAAAGAG GACAGGAAGG CTTCTGAGGA GAGACCTCTG 4680 AGGTGGGTCT TGGAGAGGAA GGACTTAGGG AGGCAGAGTG GAGGAAGTGA GAGGACACCC 4740 CAAGCCAAGA GGGCGGCAGG ACCAAAGGCT CAGAAGCCAG GGCGCTGCAG AGGGGCTGTG 4800 TGCCACAGGG TGAAGAGTTT GTGTGGCAGA AGGGCAGGGG GCTTGCATCA GGGGTGACAG 4860 CTGCTCTTTT GTCCCAGCAT AGCCCCTGTA CATCCCTGGA GAGCTGGGGC GTCCACAACT 4920 CTAAGTCACA GCCCCCATCC TAACCCTGGT GGTGCAGTGA GGGTGAGCTG TCTGTGGGCA 4980 GGAGGGAAGA CTCTTGGAGA TGAGCCTGGT GAAGGGATAA TGGCATCCCG GGCCGAGGAG 5040 CAGCACAGGC AGAGGCCTGG GGAGAGTTTA AGGAGTGTAG GGGAGGAAAT GGCAGAAGAT 5100 GAGCCAGAAA AAGAAAGGTT AGGGCAGGTC CTGGAGGACA TGAGTGGCTG TTTGGGCTTT 5160 ATCCAGCAGT GGGGGAGCCT TGGCAβGCTT GTGGCTTAGA TAGGTGCTTT AGAAAGCCCA 5220 CCAGCAGTTG CTGGGCCACC CCGCTβGCTG GGTCCTGTTC TAAGGCAGGA AATACAAGCA 5280 TGAGCAGGAA AAGACCCCCT CAAGGCTCAC GTCCTAGTGG GGAGACAAGA AACACAGATG 5340 GGCAATATAA CACGATGTCT GGTTCCAGTA AGTGCAGTGA AGAACAAGCG AGGCTGGATG 5400 CAGGGAGTGA TGGGAGGGGC TTTGTAAGGG GAGGTCGGGG GAAGCCTGTC TCAGAGGACA 5460 CCAGAATGGA GCGCAGGAGC AGCACGTGGC AGTCACATGG CAGGCCGTTA GGGCAGAGGG 5520 AGCTGGGCAG GGCACAGCAG GGCAGGAGTG TGTTTGATGT GTCCTGGGAA CCGCCCTGAG 5580 GCCGTCGTGT GGCTGGAGTG CTGCAGGTGT CAAGGAAATT GTAGGAGATG TCTCCTGAGT 5640 GTGATGGAAT ATAACCAGAT TTCCAGAAGG AACTGACATG ATCTGACTTA AAAAGGTCAG 5700 TGTGCGAAAT GGCTTGCAGG GGACAGGAGT GGGAGCAGGG AGATAGGAGA CAATGTGTAC 5760 CAGGACAGCA GAAAGACATC CCGGGTAGCC TGGAACAGGG AGACGGTGTG GAGATGGTGG 5820 CAGTCCGATA ATGAGAGCCG TAGGGCAAGG CCAGCAGGAT CCTAGAGTGA GACGGGAGGT 5880 AAAGTCACCG GGACTTGGTG TCTCCACGTC AGGGGCAGGG GAAAGGGAGA GGACAAGGGT 5940 GACCCGGGAG GTTAAAGATG GGACCGGGGC CAGACGCAGT GGCTCATGCC TGTAATCCTA 6000 GCACTTTGGG AGGCTGAGGC GGGCGGATAG CTTGAGGTCA GGAGTTTGAA ACCAGCCTGG 6060 CCAACATGGT GAAACCCCGT CTCTACTAAA ATATACAAAA ATTAGCCTGG CGTGGTGGTG 6120 CATGCCTGCA GTCCCAGCTA TTCAGGAGGC TGAGGCAACA AGAATCGCTT GAACCTGGGA 6180 GGCGGAGGTT GCAGTGAGCC GAGATCGCGC CATAGCACTC CAGCCTTAGC CTGGGCGACA 6240 GAGCGAGACC ACATC
Seq ID NO: 86 Protein sequence Protein Accession ft: XP 027172.1
11 21 31 41 51
I I I I I
MDSSPSLPLI RTPESSLHEA LDQCMTALDL FLTNQFSEAL SYLKPRTKES MYHSLTYATI 60 LEMQAMMTFD PQDILLAGNM MKEAQMLCQR HRRKSSVTDS FSSLVNRPTL GQFTEEEIHA 120 EVCYAECLLQ RAALTFLQGS SHGGAVRPRA LHDPSHACSC PPGPGRQHLF LLQDENMVSF 180 IKGGIKVRNS YQTYKELDSL VQSSQYCKGE NHPHFEGGVK LGVGAFNLTL SMLPTRILRL 240 LEFVGFSGNK DYGLLQLEEG ASGHSFRSVL CVMLLLCYHT FLTFVLGTGN VNIEEAEKLL 300 KPYLNRYPKG AIFLFFAGRI EVIKGNIDAV SDGGPGRGWG SLGVSQTSRK SGTCDILRDR 360 IDWGRGGGQE RTNQRAGAGE ALLAEQPGKT REEEAFWPG ILTGRYRTAA LQWREVEGGA
Seq ID NO: 87 DNA sequence
Nucleic Acid Accession #: AB007921
Coding sequence: 143..1363
11 21 31 41 51
I I I I I
GGTGGAGACA CCGCCTCAGG GCTCGGTGCA CAGTGGACAT TTGGGGAGCG TTGTGGGTGA 60 CCCCCACACA GGCACTGGGA ATGCAGGGGA GAGGGGGCCA AGGGGGAAAG GGGCCAGAGT 120 GTTGGCTTTG GATTCAGGAG GGATGGATTC CAGTCCTAGC TTGCCACTTA TTAGGACTCC 180 TGAGAGCAGC CTCCATGAGG CCCTGGACCA GTGCATGACC GCCCTGGACC TCTTCCTCAC 240 CAACCAGTTC TCAGAAGCAC TCAGCTACCT CAAGCCCAGA ACCAAGGAAA GCATGTACCA 300 CTCACTGACA TATGCCACCA TCCTGGAGAT GCAGGCCATG ATGACCTTTG ACCCTCAGGA 360 CATCCTGCTT GCCGGCAACA TGATGAAGGA GGCACAGATG CTGTGTCAGA GGCACCGGAG 420 GAAGTCTTCT GTAACAGATT CCTTCAGCAG CCTGGTGAAC CGCCCCACGC TGGGCCAATT 480 CACTGAAGAG GAAATCCACG CTGAGGTCTG CTATGCAGAG TGCCTGCTGC AGCGAGCAGC 540 CCTGACCTTC CTGCAGGGTT CCTCACACGG AGGGGCAGTC AGGCCCAGAG CCTTGCATGA 600 TCCCTCTCAC GCCTGCAGCT GCCCACCTGG GCCAGGCCGT CAGCATCTTT TCCTCCTGCA 660 GGACGAGAAC ATGGTGAGCT TCATCAAAGG CGGCATCAAA GTTCGAAACA GCTACCAGAC 720 CTACAAGGAG CTGGACAGCC TTGTTCAGTC CTCACAATAC TGCAAGGGTG AGAACCACCC 780 GCACTTTGAA GGAGGAGTGA AGCTTGGTGT AGGGGCCTTC AACCTGACAC TGTCCATGCT 840 TCCTACTAGG ATCCTGAGGC TGTTGGAGTT TGTGGGGTTT TCAGGAAACA AGGACTATGG 900 GCTGCTGCAG CTGGAGGAGG GAGCGTCAGG GCACAGCTTC CGCTCTGTGC TCTGTGTCAT 960 GCTCCTGCTG TGCTACCACA CCTTCCTCAC CTTCGTGCTC GGTACTGGGA ACGTCAACAT 1020 CGAGGAGGCC GAGAAGCTCT TGAAGCCCTA CCTGAACCGG TACCCTAAGG GTGCCATCTT 1080 CCTGTTCTTT GCAGGGAGGA TTGAAGTCAT TAAAGGCAAC ATTGATGCAG TGAGTGATGG 1140 GGGTCCGGGC CGGGGCTGGG GATCCCTCGG GGTCTCCCAG ACCAGCAGGA AGTCAGGCAC 1200 ATGTGACATA CTCAGGGACA GGATAGACTG GGGGCGGGGG GGGGGGCCAA GAGAGAACCA 1260 ACCAGAGAGC AGGGGCAGGA GAGGCCCTTC TGGCAGAGCA GCCTGGGAAG ACAAGGGAGG 1320 AGGAGGCATT TGTGGTGCCT GGGATTTTGA CTGGGAGATA TAGGACTGCA GCATTGCAGT 1380 GGAGGGAGGT GGAGGGAGGT GCTTGAGGGA GGCAGAGGTT AGGAAAGCCC ATCTGTTTAG 1440 GGCATGACGA TTAGGCTGGA GTCTGGTACC TCCCCTCCAT TATAGCTCTC TCCTGCTCTT 1500 TCATTTTGTT ACTAAAAACC AGAGTCCTAG GCGGGGGCTG TATTTGAGCC CAACGTCATG 1560
TAAGACTTAG GAGGTAAAAC CAGGACTGGA GGCCAGATCT CCTGGCTCCT GGGGCCCCAC 1620
CTGAGCCTAG CACAGGGCTG GACCACTATG CCCTGGAGGA GTCCCGGTCT GCTGTGGTGT 1680
TGGGAGGTTC GGAGGATGCA GAGGGGTTGG GGCTGGGTGG GCACCCGTCA GGCTGACCAG 1740
AAGGTGCCTG CAGGCCATCC GGCGTTTCGA GGAGTGCTGT GAGGCCCAGC AGCACTGGAA 1800
GCAGTTCCAC CACATGTGCT ACTGGGAGCT GATGTGGTGC TTCACCTACA AGGGCCAGTG 1860
GAAGATGTCC TACTTCTACG CCGACCTGCT CAGCAAGGAG AACTGCTGGT CCAAGGTGGG 1920
CTGATGCCAC GTGTTAGGGG CATTGGGTGA CCAGGGCTGA CTGTGTGCCT CCAGACCACG 1980
GGCCAAATCC CTAACTGAAC ACAGATGTCT CAGCTGGAAT CTAAACATAA CCTTAAATTC 2040
TAATAGGACT CAGGCTTGGA AGGAACTAAA GACCACAAGA GAAACTTCTG AACCACAATG 2100
TGTCACAAAG AGATTTCTAG TCACAAAGGA CAGAAACATG GCTCCCTCTG TCCAGTAGAA 2160
CTGTTTCTGT GGTAGAAATG TTCTACTTAT GCACTGCCCA AATATGGTAG TCACCAGCCA 2220
CATGTGCACA CTGAGCACAT GAAATGTGCC TAGTGCAACT GGGAAACTGA TTGTTTTCAG 2280
TTTTATTTAA TTTTAATTAA CTAAATGTTA AATTTAAATA GCCATGTAGG GCTTGTGGCC 2340
ACTATATTGG ACTATGCAGG TCCAAAACAC AAAAGGCTCA TATAACTGAA CATTCTTGGC 2400
ACATCCGACT TCAGGTAGGG CTGGATCCAG GAATTCAAAT GATGTCGTCT GGCTTGGTCT 2460
TTCCATTTGT GGCTGTGCTC TCTCCTATGA CATCTTTGTT TCTGCTGCAT CTTTGCAGGA 2520
AGGTTCTCTC CATGTGACAG GCAAGGTGGC CACGGGCTGC TTCTACTCAT ATCCTCCCCT 2580
TGGTTTCAAC CAGAGTCCCA CAGTTTGAGC CTCACTGGTC TGACTTGTCA CCTGCCAATG 2640
CCTGGAACAG AGGGGTGGGA AGATTCCTCA TGGGCTGAGA GTAGGAGAGG GGTGGTTCCA 2700
CAGAAGAAAA TGATGCACCC AGAAATAGTG GAGGGATTAA CAAGATGCCA TACAGGCAAA 2760
ACAAAGCCAA ACAGATGCCC GCCTACCAAA GATGAAATTT ATCATGGTAA GTATTGAAAT 2820
AAGTGTTAGC TTGTACCATC ATAGTAATGA TAGTGCAGAA ATTGGAACCA AGAGTCTTAC 2880
AACCACCTAG CTCAGCAAAC GTCTAATCTG TTATTTGTAA ATACACAGGA CATGTGTCTT 2940
CATGGCTTCA TCCCCTGCCC ATGGCAGACA TTGCTAATCA ATCCTCTGCC ATGAGCCTAG 3000
CTGTGACCTT AGATACCTTC CCTGCAAAGC TCCAGGCAGC CGTTAGAACT GACCCACATT 3060
GGCACCTGTT AGGAGACCTG TCATCTGCAT CTGGTCCCTC CCCCTCCTCT GCATGGAGGT 3120
CTCTTCCGTA GCCCTGCCTG GGGACCAAGC TGAAGGGGAA TTCTCTGGGT CTGGGGCAGG 3180
TGGGGCTGGG GAAGGGAGCA GGCTTCTACT GAGCTCTCAA CATGTCTGGC ACCTGTCATG 3240
TCCTCCACAC CACACCCAGT GAGGAGAAGT TATTATCTCC ATTGGGCACA TGAGGGCCAC 3300
TGATGCTAAG CGAGGACTGT GACTTTCCCA CCCACATGGC TGTTGGTGAC AGACACCGGA 3360
TTTGAGGACA GTCCTGTGTG ACTCAGAGGC CTCTGCTTCT CTCTTGCTCC TAGAGTCCTC 3420
CTGAGGAGTC GGGGCTTGCC CTGAGCCCAC CCTGCTGTTG AAGGTGCTTC CTCAGGCCCA 3480
GCTCCCATGG CCCCCACACC CCCTCCTCAT CACCTCCTAC TCCCAAAAAG GACAAAGCCT 3540
CAGGGAACCT TTTTTCTTTT TTTAGAGACG GGGTCTTGCT ATGTTGGTCA GGCTGGTCTT 3600
GAACTCCTGG GCCCAGGCAA TCTTCCCGCC TCTGCCTCCT AAAGTGCTGG GATTCTGGGC 3660
CTTAGGGAAC CTTTTTGAAC TGAAAGTGAC GCTCGAAGCC TTCCTGTAGA GTGAGGTGGG 3720
TGGCTGGGGC TAACCATATG GGGAAGGAGA GACCTGGTβG GGGCACACAG CTGCTATATA 3780
GAGGAACAGA AGGTGGGCCA GGCCTCCCAG CTGTCAGGAA ATCTGGCTCA GTCCCCAGAC 3840
CGCTGTGTGG CTTTGGGGTG GCCAGTCCCT CTCTCTCTGC AACACTCTCC TCATGAGGAC 3900
TTCTGTGAAA AATGGGGGTT GTAACCCTCT GAGTTCTGGG GCCCCACCCA TTTCTAATCT 3960
CCAGAACTTG GCCACCACAG ACTCCACCAA CTTCTAGTCC TGGGGCCTGG GCCTCTGGCC 4020
ATTGCCATAG GCACCACCTG CTCTGTGCAG GCAGCGCCCC CCTCTGCCAG GATCCTCCGA 4080
GGTCAGCTGC TGGGTCTGAC CCGCAGACCC TGGCTGAGCG ACGGATGAAC GGAGTATGCA 4140
GACACAGGCT TGCTTGTCAG CAGATGGGGG ACCCCTGCCA GAGTCAGCAG CGGCCCCCAT 4200
AAGCCTGCCA CGCTTGCATT TATTTAGTAC AGATGTAATG ACAAAGGCCT AAAGCAAACT 4260
CCATTTGTGG GTAATTAACA TTGTCGCCCC CCCAGAAAGA GGAGTCCTCC GCATGATGAT 4320
TAAAGGCCAG GTTCCGAGGC CTAAGTAAAC CAACTTATCT AGATCAATTC CCTTACTTCT 4380
TGTTATCTAC TCTGAGAGAA TTCAGCTGCC TTCAGCCAAA TCCTTTCCCG AAGCTTTTGC 4440
AAAACCTCCG AGCCTTCCAA GGTTTGCTTC TTTCTGTAAT TTTTCTCACC ACCCTGACCT 4500
ATCTCCTGCA GTCAGCCCTG TGGAGGCCTT TGTGTTTCCC CCAGTGCTGG CAGCCTAGAG 4560
GCTGAGATGG CCAGAAACAA GGTGGTGACA GTGGCGTGCT CAGGGCTTGG GAAACCCAAG 4620
GAGCTAAAGG CATGCCCAGG CAACCAAAGA GGACAGGAAG GCTTCTGAGG AGAGACCTCT 4680
GAGGTGGGTC TTGGAGAGGA AGGACTTAGG GAGGCAGAGT GGAGGAAGTG AGAGGACACC 4740
CCAAGCCAAG AGGGCGGCAG GACCAAAGGC TCAGAAGCCA GGGCGCTGCA GAGGGGCTGT 4800
GTGCCACAGG GTGAAGAGTT TGTGTGGCAG AAGGGCAGGG GGCTTGCATC AGGGGTGACA 4860
GCTGCTCTTT TGTCCCAGCA TAGCCCCTGT ACATCCCTGG AGAGCTGGGG CGTCCACAAC 4920
TCTAAGTCAC AGCCCCCATC CTAACCCTGG TGGTGCAGTG AGGGTGAGCT GTCTGTGGGC 4980
AGGAGGGAAG ACTCTTGGAG ATGAGCCTGG TGAAGGGATA ATGGCATCCC GGGCCGAGGA 5040
GCAGCACAGG CAGAGGCCTG GGGAGAGTTT AAGGAGTGTA GGGGAGGAAA TGGCAGAAGA 5100
TGAGCCAGAA AAAGAAAGGT TAGGGCAGGT CCTGGAGGAC ATGAGTGGCT GTTTGGGCTT 5160
TATCCAGCAG TGGGGGAGCC TTGGCAGGCT TGTGGCTTAG ATAGGTGCTT TAGAAAGCCC 5220
ACCAGCAGTT GCTGGGCCAC CCCGCTGGCT GGGTCCTGTT CTAAGGCAGG AAATACAAGA 5280
ATGAGCAGGA AAAGACCCCC TCAAGGCTCA CGTCCTAGTG GGGAGACAAG AAACACAGAT 5340
GGGCAATATA ACACGATGTC TGβTTCCAGT AAGTGCAGTG AAGAACAAGC GAGGCTGGAT 5400
GCAGGGAGTG ATGGGAGGGG CTTTGTAAGG GGAGGTCGGG GGAAGCCTGT CTCAGAGGAC 5460
ACCAGAATGG AGCGCAGGAG CAGCACGTGG CAGTCACATG GCAGGCCGTT AGGGCAGAGG 5520
GAGCTGGGCA GGGCACAGCA GGGCAGGAGT GTGTTTGATG TGTCCTGGGA ACCGCCCTGA 5580
GGCCGTCGTG TGGCTGGAGT GCTGCAGGTG TCAAGGAAAT TGTAGGAGAT GTCTCCTGAG 5640
TGTGATGGAA TATAACCAGA TTTCCAGAAG GAACTGACAT GATCTGACTT AAAAAGGTCA 5700
GTGTGCGAAA TGGCTTGCAG GGGACAGGAG TGGGAGCAGG GAGATAGGAG ACAATGTGTA 5760
CCAGGACAGC AGAAAGACAT CCCGGGTAGC CTGGAACAGG GAGACGGTGT GGAGATGGTG 5820
GCAGTCCGAT AATGAGAGCC GTAGGGCAAG GCCAGCAGGA TCCTAGAGTG AGACGGGAGG 5880
TAAAGTCACC GGGACTTGGT GTCTCCACGT CAGGGGCAGG GGAAAGGGAG AGGACAAGGG 5940
TGACCCGGGA GGTTAAAGAT GGGACCGGGG CCAGACGCAG TGGCTCATGC CTGTAATCCT 6000
AGCACTTTGG GAGGCTGAGG CGGGCGGATG GCTTGAGGTC AGGAGTTTGA AACCGGCCTG 6060
GCCAACATGG TGAAACCCCG TCTCTACTAA AATATACAAA AATTAGCCTG GCGTGGTGGT 6120
GCATGCCTGC AGTCCCAGCT ATTCAGGAGG CTGAGGCGAC AAGAATCGCT TGAACCTGGG 6180
AGGCGGAGGT TGCAGTGAGC CGAGATCGCG CCATAGCACT CCAGCCTTAG CCTGGGCGAC 6240 AGAGCGAGAC CACATC
Seq ID NO: 88 Protein sequence Protein Accession ft: BAA32297.1 1 11 21 31 41 51 J 1 | 1 |1 1 1 | 1 | 1 VETPPQGSVH SGHLGSWGD PHTGTGNAGE RGPRGKGARV LALDSGGMDS SPSLPLIRTP 60
ESSLHEALDQ CMTALDLFLT NQFSEALSYL KPRTKEΞMYH SLTYATILEM QAMMTFDPQD 120
ILLAGNMMKE AQMLCQRHRR KSSVTDSFSS LVNRPTLGQF TEEEIHAEVC YAECLLQRAA 180
LTFLQGSSHG GAVRPRALHD PSHACSCPPG PGRQHLFLLQ DENMVSFIKG GIKVRNSYQT 240
YKELDSLVQS SQYCKGENHP HFEGGVKLGV GAFNLTLSML PTRILRLLEF VGFSGNKDYG 300
LLQLEEGASG HSFRSVLCVM LLLCYHTFLT FVLGTGNVNI EEAEKLLKPY LNRYPKGAIF 360
LFFAGRIEVI KGNIDAVSDG GPGRGWGSLG VSQTSRKSGT CDILRDRIDW GRGGGPRENQ 420
PESRGRRGPS GRAAWEDKGG GGICGAWDFD WEI
Seq ID NO: 89 DNA sequence
Coding sequence: 73..1725
11 21 31 41 51
I I I I
AAGGAGGCGG CCTCCGGGAA AAGCGACCGC AGGACTCCTG AGAGCAGCCT CCATGAGGCC 60
CTGGACCAGT GCATGACCGC CCTGGACCTC TTCCTCACCA ACCAGTTCTC AGAAGCACTC 120
AGCTACCTCA AGCCCAGAAC CAAGGAAAGC ATGTACCACT CACTGACATA TGCCACCATC 180
CTGGAGATGC AGGCCATGAT GACCTTTGAC CCTCAGGACA TCCTGCTTGC CGGCAACATG 240
ATGAAGGAGG CACAGATGCT GTGTCAGAGG CACCGGAGGA AGTCTTCTGT AACAGATTCC 300
TTCAGCAGCC TGGTGAACCG CCCCACGCTG GGCCAATTCA CTGAAGAAGA AATCCACGCT 360
GAGGTCTGCT ATGCAGAGTG CCTGCTGCAG CGAGCAGCCC TGACCTTCCT GCAGGACGAG 420
AACATGGTGA GCTTCATCAA AGGCGGCATC AAAGTTCGAA ACAGCTACCA GACCTACAAG 480
GAGCTGGACA GCCTTGTTCA GTCCTCACAA TACTGCAAGG GTGAGAACCA CCCGCACTTT 540
GAAGGAGGAG TGAAGCTTGG TGTAGGGGCC TTCAACCTGA CACTGTCCAT GCTTCCTACT 600
AGGATCCTGA GGCTGTTGGA GTTTGTGGGG TTTTCAGGAA ACAAGGACTA TGGGCTGCTG 660
CAGCTGGAGG AGGGAGCGTC AGGGCACAGC TTCCGCTCTG TGCTCTGTGT CATGCTCCTG 720
CTGTGCTACC ACACCTTCCT CACCTTCGTβ CTCGGTACTG GGAACGTCAA CATCGAGGAG 780
GCCGAGAAGC TCTTGAAGCC CTACCTGAAC CGGTACCCTA AGGGTGCCAT CTTCCTGTTC 840
TTTGCAGGGA GGATTGAAGT CATTAAAGGC AACATTGATG CAGCCATCCG GCGTTTCGAG 900
GAGTGCTGTG AGGCCCAGCA GCACTGGAAG CAGTTTCACC ACATGTGCTA CTGGGAGCTG 960
ATGTGGTGCT TCACCTACAA GGGCCAGTGG AAGATGTCCT ACTTCTACGC CGACCTGCTC 1020
AGCAAGGAGA ACTGCTGGTC CAAGGCCACC TACATTTACA TGAAGGCCGC CTACCTCAGC 1080
ATGTTTGGGA AGGAGGACCA CAAGCCGTTC GGGGACGACG AAGTGGAATT ATTTCGAGCT 1140
GTGCCAGGCC TGAAGCTCAA GATTGCTGGG AAATCTCTAC CCACAGAGAA GTTTGCCATC 1200
CGGAAGTCCC GGCGCTACTT CTCCTCCAAC CCTATCTCGC TGCCAGTGCC TGCTCTGGAA 1260
ATGATGTACA TCTGGAACGG CTACGCCGTG ATTGGGAAGC AGCCGAAACT CACGGATGGG 1320
ATACTTGAGA TTATCACTAA GGCTGAAGAG ATGCTGGAGA AAGGCCCAGA GAACGAGTAC 1380
TCAGTGGATG ACGAGTGCTT GGTGAAATTG TTGAAAGGCC TGTGTCTGAA ATACCTGGGC 1440
CGTGTCCAGG AGGCCGAGGA GAATTTTAGG AGCATCTCTG CCAATGAAAA GAAGATTAAA 1500
TATGACCACT ACTTGATCCC AAACGCCCTG CTGGAGCTGG CCCTGCTGCT TATGGAGCAA 1560
GACAGAAACG AAGAGGCCAT CAAACTTTTG GAATCTGCCA AGCAAAACTA CAAGAATTAC 1620
TCCATGGAGT CAAGGACACA CTTTCGAATC CAGGCAGCCA CACTCCAAGC CAAGTCTTCC 1680
CTAGAGAACA GCAGCAGATC CATGGTCTCA TCAGTGTCCT TGTAGCTTTG TGCAGCAGTT 1740
CCGGGCTGGA AGACAGAGAC AGCTGGACAG AGCTCCTGAA AACATTTCAA AATACCCCCT 1800
CCCCCTGCCC TGCCCTGCCT TTGGGGTCCA CCGGCACTCC AGTTGGATGG CACAACATAG 1860
TGTATCCGTG CAGAAGCCGA GCTGGCATTT TCACCAGTGT AGCCAAGGGC CTTTGCCAAG 1920
GGCAGAGCAG GTGGAGCCCT CTGCCTGCCC TATCACACAT ACGGGTACTT GCTTTTCACT 1980
GTGATGTTTA AGAGAATGTA TGAACAGTTT ACATTTTCCT TAGAAATACA TTGATGGGAT 2040
CACAGTTGGC TTTAAAAACC AACAACAATC AACCACCTGT AAGTCTTTGT CTTCACCTAT 2100
TATCATCTGG AGGTAAATCT CTTTATATGA TGATGCCAAA GGGCAAATTG CTTTTCAAAT 2160
TCAGCAAGTT CTCAGCTTGT GTGACGGAAG GTCCTTCAGA GGACCTGAGG AATGCCTGGG 2220
AGAGGCTAAG CCTCAGGCTT CAATGCTTCT GGGGTTGGGC ATGAGGATGT ACACAGACAC 2280
CCACTACCTT ACTACTCACA CTTCATTTCA CTCCTTTTGT AAATTTCCAA TTTAAAAATC 2340
AAGCACGTCT TTTTAGTGAG ATAAAATCTG AGCTCTTCTG TAGAAAAATC AATCTCTACC 2400
AGTAGAAAAT GCCAGGGCTT GATGGAAGAG CTGTGTAGCC CTTTCTATGC CAAAGCCAGG 2460
AAATTTGGGG GGCAGGAGGA GGTTCTCAGA ATCCAGTCTG TATCTTTGCT GTATGCCAAA 2520
CTGAAACCAC TGGGAATAAT TTATGAAACA TAAAAATCTT CTGTACTTCA CTCCAAGGTA 2580
CATTTGCTTA CTGACAGCAT TTTTGTTAAA ACTGTTATTC TTGAAAAAAA AAAAAAAAAA 2640
AA
Seq ID NO: 90 Protein sequence Protein Accession #: AAC39582.1
11 21 31 41 51
I I I I I
KEAASGKSDR RTPESSLHEA LDQCMTALDL FLTNQFSEAL ΞYLKPRTKES MYHSLTYATI 60 LEMQAMMTFD PQDILLAGNM MKEAQMLCQR HRRKSSVTDS FSSLVNRPTL GQFTEEEIHA 120 EVCYAECLLQ RAALTFLQDE NMVSFIKGGI KVRNSYQTYK ELDSLVQSSQ YCKGENHPHF 180 EGGVKLGVGA FNLTLSMLPT RILRLLEFVG FSGNKDYGLL QLEEGASGHS FRSVLCVMLL 240 LCYHTFLTFV LGTGNVNIEE AEKLLKPYLN RYPKGAIFLF FAGRIEVIKβ NIDAAIRRFE 300 ECCEAQQHWK QFHHMCYWEL MWCFTYKGQW KMSYFYADLL SKENCWSKAT YIYMKAAYLS 360 MFGKEDHKPF GDDEVELFRA VPGLKLKIAG KSLPTEKFAI RKΞRRYFSSN PISLPVPALE 420 MMYIWNGYAV IGKQPKLTDG ILEIITKAEE MLEKGPENEY SVDDECLVKL LKGLCLKYLG 480 RVQEAEENFR SISANEKKIK YDHYLIPNAL LELALLLMEQ DRNEEAIKLL ESAKQNYKNY 540 SMESRTHFRI QAATLQAKSS LENSSRSMVS SVSL
Seq ID NO: 91 DNA sequence
Nucleic Acid Accession ff: Eos sequence
Coding sequence: 31..906 11 21 31 41 51
I I I I
CGGGTCGACC CACGCGTCCG GGGAGAAAGG ATGGCCGGCC T IGGCGGCGCG GTTGGTCCTG 60
CTAGCTGGGG CAGCGGCGCT GGCGAGCGGC TCCCAGGGCG ACCGTGAGCC GGTGTACCGC 120
GACTGCGTAC TGCAGTGCGA AGAGCAGAAC TGCTCTGGGG GCGCTCTGAA TCACTTCCGC 180
TCCCGCCAGC CAATCTACAT GAGTCTAGCA GGCTGGACCT GTCGGGACGA CTGTAAGTAT 240
GAGTGTATGT GGGTCACCGT TGGGCTCTAC CTCCAGGAAG GTCACAAAGT GCCTCAGTTC 300
CATGGCAAGT GGCCCTTCTC CCGGTTCCTG TTCTTTCAAG AGCCGGCATC GGCCGTGGCC 360
TCGTTTCTCA ATGGCCTGGC CAGCCTGGTG ATGCTCTGCC GCTACCGCAC CTTCGTGCCA 420
GCCTCCTCCC CCATGTACCA CACCTGTGTG GCCTTCGCCT GGGTGTCCCT CAATGCATGG 480
TTCTGGTCCA CAGTYTTCCA CACCAGGGAC ACTGACCTCA CAGAGAAAAT GGACTACTTC 540
TGTGCCTCCA CTGTCATCCT ACACTCAATC TACCTGTGCT GCGTCAGCCT CATCCGCTTC 600
GACTATGGCT ACAACCTGGT GGCCAACGTG GCTATTGGCC TGGTCAACGT GGTGTGGTGG 660
CTGGCCTGGT GCCTGTGGAA CCAGCGGCGG CTGCCTCACG TGCGCAAGTG CGTGGTGGTG 720
GTCTTGCTGC TGCAGGGGCT GTCCCTGCTC GAGCTGCTTG ACTTCCCACC GCTCTTCTGG 780
GTCCTGGATG CCCATGCCAT CTGGCACATC AGCACCATCC CTGTCCACGT CCTCTTTTTC 840
AGCTTTCTGG AAGATGACAG CCTGTACCTG CTGAAGGAAT CAGAGGACAA GTTCAAGCTG 900
GACTGAAGAC CTTGGAGCGA GTCTGCCCCA GTGGGGATCC TGCCCCCGCC CTGCTGGCCT 960
CCCTTCTCCC CTCAACCCTT GAGATGATTT TCTCTTTTCA ACTTCTTGAA CTTGGACATG 1020
AAGGATGTGG GCCCAGAATC ATGTGGCCAG CCCACCCCCT GTTGGCCCTC ACCAGCCTTG 1080
GAGTCTGTTC TAGGGAAGGC CTCCCAGCAT CTGGGACTCG AGAGTGGGCA GCCCCTCTAC 1140
CTCCTGGAGC TGAACTGGGG TGGAACTGAG TGTGCTCTTA GCTCTACCGG GAGGACAGCT 1200
GCCTGTTTCC TCCCCATCAG CCTCCTCCCC ACATCCCCAG CTGCCTGGCT GGGTGCTGAA 1260
GCCCTCTGTC TACCTGGGAG ACCAGGGACC ACAGGCCTTA GGGATACAGG GGGTCCCCTT 1320
CTGTTACCAC CCCCCACCCT CCTCCAGGAC ACCACTAGGT GGTGCTGGAT GCTTGTTCTT 1380
TGGCCAGCCA AGGTTCACGG CGATTCTCCC CATGGGATCT TGAGGGACCA AGCTGCTGGG 1440
ATTGGGAAGG AGTTTCACCC TGACCRTTGC CCTAGCCAGG TTCCCAGGAG, GCCTCACCAT 1500
ACTCCCTTTC AGGGCCAGGG CTCCAGCAAG CCCAGGGCAA GGATCCTGTG CTGCTGTCTG 1560
GTTGAGAGCC TGCCACCGTG TGTCGGGAGT GTGGGCCAGG CTGAGTGCAT AGGTGACAGG 1620
GCCGTGAGCA TGGGCCTGGG TGTGTGTGAG CTCAGGCACT AGGTGCGCAG TGTGGAGACG 1680
GGTGTTGTCG GGGAAGAGGT GTGGCTTCAA AGTGTTGTGT GTGCAGGGGG TKGGTGTGTT 1740
AAGCGTGGGT TAGGGGAACG TGTGTGCGCG TGCTGGTGGG CATGTGAGAT GAGTGACTGC 1800
CGGTGAATGT GTCCACAGTT GAGAGGTTGG AGCAGGATGA GGGAATCCTG TCACCATCAA 1860
TAATCACTTG TGGAGCGCCA CTTGGCCCAA GACGCCACCT GGGCGGACAG CAGGAGCTCT 1920
CCATGGCCAG GCTGCCTGTG TGCATGTTCC CTGTCTGGTG CCCCTTTGCC CGCCTCCTGC 1980
AAACCTCACA GGGTCCCCAC ACAACAGTGC CCTCCAGAAG CAGCCCCTCG GAGGCAGAGG 2040
AAGGAAAATG GGGATGGCTG GGGCTCTCTC CATCCTCCTT TTCTCCTTGC CTTCGCATGG 2100
CTGGCCTTCC CCTCCAAAAC CTCCATTCCC CTGCTGCCAG CCCCTTTGCC ATAGCCTGAT 2160
TTTGGGGAGG AGGAAGGGGC GATTTGAGGG AGAAGGGGAG AAAGCTTATG GCTGGGTCTG 2220
GTTTCTTCCC TTCCCAGAGG GTCTTACTGT TCCAGGGTGG CCCCAGGGCA GGCAGGGGCC 2280
ACACTATGCC TGCGCCCTGG TAAAGGTGAC CCCTGCCATT TACCAGCAGC CCTGGCATGT 2340
TCCTGCCCCA CAGGAATAGA ATGGAGGGAG CTCCAGAAAC TTTCCATCCC AAAGGCAGTC 2400
TCCGTGGTTG AAGCAGACTG GATTTTTGCT CTGCCCCTGA CCCCTTGTCC CTCTTTGAGG 2460
GAGGGGAGCT ATGCTAGGAC TCCAACCTCA GGGACTCGGG TGGCCTGCGC TAGCTTCTTT 2520
TGATACTGAA AACTTTTAAG GTGGGAGGGT GGCAAGGGAT GTGCTTAATA AATCAATTCC 2580
AAGCCTCAAA AAAAAAAAAA AAAAAAAAAA AAAAAA
Seq ID NO: 92 Protein sequence Protein Accession ft : Eos sequence
11 21 31 41 51
I I I I I
MAGLAARLVL LAGAAALASG SQGDREPVYR DCVLQCEEQN CSGGALNHFR SRQPIYMSLA 60 GWTCRDDCKY ECMWVTVGLY LQEGHKVPQF HGKWPFSRFL FFQEPASAVA SFLNGLASLV 120 MLCRYRTFVP ASSPMYHTCV AFAWVSLNAW FWSTVFHTRD TDLTEKMDYF CASTVILHSI 180 YLCCVRTVGL QHPAWSAFR ALLLLMLTVH VSYLSLIRFD YGYNLVANVA IGLVNWWWL 240 AWCLWNQRRL PHVRKCWW LLLQGLSLLE LLDFPPLFWV LDAHAIWHIS TIPVHVLFFS 300 FLEDDSLYLL KESEDKFKLD
Seq ID NO: 93 DNA sequence
Nucleic Acid Accession ft: NM_033419.1
Coding sequence: 18..980
11 21 31
CGAGCCAGGG AGAAAGGATG GCCGGCCTGG CGGCGCGGTT GGTCCTGCTA GCTGGGGCAG 60
CGGCGCTGGC GAGCGGCTCC CAGGGCGACC GTGAGCCGGT GTACCGCGAC TGCGTACTGC 120
AGTGCGAAGA GCAGAACTGC TCTGGGGGCG CTCTGAATCA CTTCCGCTCC CGCCAGCCAA 180
TCTACATGAG TCTAGCAGGC TGGACCTGTC GGGACGACTG TAAGTATGAG TGTATGTGGG 240
TCACCGTTGG GCTCTACCTC CAGGAAGGTC ACAAAGTGCC TCAGTTCCAT GGCAAGTGGC 300
CCTTCTCCCG GTTCCTGTTC TTTCAAGAGC CGGCATCGGC CGTGGCCTCG TTTCTCAATG 360
GCCTGGCCAG CCTGGTGATG CTCTGCCGCT ACCGCACCTT CGTGCCAGCC TCCTCCCCCA 420
TGTACCACAC CTGTGTGGCC TTCGCCTGGG TGTCCCTCAA TGCATGGTTC TGGTCCACAG 480
TTTTCCACAC CAGGGACACT GACCTCACAG AGAAAATGGA CTACTTCTGT GCCTCCACTG 540
TCATCCTACA CTCAATCTAC CTGTGCTGCG TCAGGACCGT GGGGCTGCAG CACCCAGCTG 600
TGGTCAGTGC CTTCCGGGCT CTCCTGCTGC TCATGCTGAC CGTGCACGTC TCCTACCTGA 660
GCCTCATCCG CTTCGACTAT GGCTACAACC TGGTGGCCAA CGTGGCTATT GGCCTGGTCA 720
ACGTGGTGTG GTGGCTGGCC TGGTGCCTGT GGAACCAGCG GCGGCTGCCT CACGTGCGCA 780
AGTGCGTGGT GGTGGTCTTG CTGCTGCAGG GGCTGTCCCT GCTCGAGCTG CTTGACTTCC 840
CACCGCTCTT CTGGGTCCTG GATGCCCATG CCATCTGGCA CATCAGCACC ATCCCTGTCC 900
ACGTCCTCTT TTTCAGCTTT CTGGAAGATG ACAGCCTGTA CCTGCTGAAβ GAATCAGAGG 960
ACAAGTTCAA GCTGGACTGA AGACCTTGGA GCGAGTCTGC CCCAGTGGGG ATCCTGCCCC 1020
CGCCCTGCTG GCCTCCCTTC TCCCCTCAAC CCTTGAGATG ATTTTCTCTT TTCAACTTCT 1080
TGAACTTGGA CATGAAGGAT GTGGGCCCAG AATCATGTGG CCAGCCCACC CCCTGTTGGC 1140 CCTCACCAGC CTTGGAGTCT GTTCTAGGGA AGGCCTCCCA GCATCTGGGA CTCGAGAGTG 1200 GGCAGCCCCT CTACCTCCTG GAGCTGAACT GGGGTGGAAC TGAGTGTGCT CTTAGCTCTA 1260 CCGGGAGGAC AGCTGCCTGT TTCCTCCCCA TCAGCCTCCT CCCCACATCC CCAGCTGCCT 1320 GGCTGGGTCC TGAAGCCCTC TGTCTACCTG GGAGACCAGG GACCACAGGC CTTAGGGATA 1380 CAGGGGGTCC CCTTCTGTTA CCACCCCCCA CCCTCCTCCA GGACACCACT AGGTGGTGCT 1440 GGATGCTTGT TCTTTGGCCA GCCAAGGTTC ACGGCGATTC TCCCCATGGG ATCTTGAGGG 1500 ACCAAGCTGC TGGGATTGGG AAGGAGTTTC ACCCTGACCA TTGCCCTAGC CAGGTTCCCA 1560 GGAGGCCTCA CCATACTCCC TTTCAGGGCC AGGGCTCCAG CAAGCCCAGG GCAAGGATCC 1620 TGTGCTGCTG TCTGGTTGAG AGCCTGCCAC CGTGTGTCGG GAGTGTGGGC CAGGCTGAGT 1680 0 GCATAGGTGA CAGGGCCGTG AGCATGGGCC TGGGTGTGTG TGAGCTCAGG CCTAGGTGCG 1740 CAGTGTGGAG ACGGGTGTTG TCGGGGAAGA GGTGTGGCTT CAAAGTGTGT GTGTGCAGGG 1800 GGTGGGTGTG TTAGCGTGGG TTAGGGGAAC GTGTGTGCGC GTGCTGGTGG GCATGTGAGA 1860 TGAGTGACTG CCGGTGAATG TGTCCACAGT TGAGAGGTTG GAGCAGGATG AGGGAATCCT 1920 GTCACCATCA ATAATCACTT GTGGAGCGCC AGCTCTGCCC AAGGCGCCAC CTGGGCGGAC 1980 5 AGCCAGGAGC TCTCCATGGC CAGGCTGCCT GTGTGCATGT TCCCTGTCTG GTGCCCCTTT 2040 GCCCGCCTCC TGCAAACCTC ACAGGGTCCC CACACAACAG TGCCCTCCAG AAGCAGCCCC 2100 TCGGAGGCAG AGGAAGGAAA ATGGGGATGG CTGGGGCTCT CTCCATCCTC CTTTTCTCCT 2160 TGCCTTCGCA TGGCTGGCCT TCCCCTCCAA AACCTCCATT CCCCTGCTGC CAGCCCCTTT 2220 GCCATAGCCT GATTTTGGGG AGGAGGAAGG GGCGATTTGA GGGAGAAGGG GAGAAAGCTT 2280 0 ATGGCTGGGT CTGGTTTCTT CCCTTCCCAG AGGGTCTTAC TGTTCCAGGG TGGCCCCAGG 2340 GCAGGCAGGG GCCACACTAT GCCTGCGCCC TGGTAAAGGT GACCCCTGCC ATTTACCAGC 2400 AGCCCTGGCA TGTTCCTGCC CCACAGGAAT AGAATGGAGG GAGCTCCAGA AACTTTCCAT 2460 CCCAAAGGCA GTCTCCGTGG TTGAAGCAGA CTGGATTTTT GCTCTGCCCC TGACCCCTTG 2520 TCCCTCTTTG AGGGAGGGGA GCTATGCTAG GACTCCAACC TCAGGGACTC GGGTGGCCTG 2580 5 CGCTAGCTTC TTTTGATACT GAAAACTTTT AAGGTGGGAG GGTGGCAAGG GATGTGCTTA 2640 ATAAATCAAT TCCAAGCCTC AAAAAAAAAA AAAAAAAAAA AA
Seq ID NO: 94 Protein sequence Protein Accession ft: NP 219487.1 0
11 21 31 41 51
MKDVGPESCG QPTPCWPSPA LESVLGKASQ HLGLESGQPL YLLELNWGGT ECALSSTGRT 60
AACFLPISLL PTSPAAWLGP EALCLPGRPG TTGLRDTGGP LLLPPPTLLQ DTTRWCWMLV 120 5 LWPAKVHGDS PHGILRDQAA GIGKEFHPDH CPSQVPRRPH HTPFQGQGSS KPRARILCCC 180 LVESLPPCVG SVGQAECIGD RAVSMGLGVC ELRPRCAVWR RVLSGKRCGF KVCVCRGWVC
Seq ID NO: 95 DNA sequence
Nucleic Acid Accession ft: XM_090469 0 Coding sequence:
11 21 31 41 51
I I I I
ATGGGGTTTG GAGACCAGGG AACGGTGGAA GGGAGCCTAβ GAACGTCGAA A 1GATAGCTCC 60 5 TGCCGCGTGC TGGACAGGAC GCAGGTGAAC AAGCCCTGCC TGCTGGAGGC TGCCAAGCAC 120 AGCCCACACC CCTTGCATGG ACAGTCGGTC AACAGCCACC CATCAGGTGC TCATCAGAAA 180 CCACCTGAAG TGAAAATGTT TGGAGCCAGT CAAGGTTTGC TGACAATGGA AACAAACCAG 240 TCCCTGGCAC AAGGCACAGG CTGCTCAGTG TGCTGGGAGG TGAACGGCCC AGGGTTGGAA 300 ATGTCTCTTC CTGGAGTGCT CAGTGCTGAT GCTGGCCAGG TGGAGCACAG AAGACAAATG 360 0 AACTCCGCAG ATACTGACTG GGGAACTGAG GAGGGACCAG GAAGTCTAGA TTTCGCCGTG 420 GCTGCCCACC AGGAAGACAC TTTCTTTTTG AAAGACATCA AGCACACAAG TACGTTCAGG 480 CAATCAGTTC AGCAGCAGAA TTGCATTTAC AGCCCCAGAG AAAAACCCTG TGGGAATGTC 540 AGGGCACCTT GCGCGCCACC AAGGCGAGAG GCCCCGCTTG CCCTCAGCAG GCCCTGGCGG 600 CTCAGCCGCA GCCCGGCGCC GTCCCCACGT ACACCCATGG CGCCCTTCCC GACCTCTGAC 660 5 CGCGAGCTAG ACGCGCCAGG CCCGCCCCCC GGGCTGCGGA GCTCGGCAGC AGCCCCTCAC 720 TGCCTGCCCG CGGCTCCAGA AGCCCAGAAA CTCTTCTTCC TGCTGCCCCT TTATCCAGAT 780 GGCAGCCCAC CACCTAAGGA CATCTTGCAG ACGCTCCAGC ACAAGGCACC TGGGAAGAGA 840 CTGCATCAAG AATCACCAGG TTCATTTCCA ATAG6TTTAT GTAACAGAAC AGCTGAACCA 900 TGTATCAAAG GGGCTCTGGG TGTGGCTGCT GAAGCAGCAT TTCACTTACA GTTTTCCAGT 960 0 GAATGA
Seq ID NO: 96 Protein sequence Protein Accession tf: XP_090469 5 11 21 31 41 51
I I I I
MGFGDQGTVE G 1SLGTSKDSS CRVLDRTQVN KPCLLEAAKH SPHPLHGQSV NSHPSGAHQK 60 PPEVKMFGAS QGLLTMETNQ SLAQGTGCSV CWEVNGPGLE MSLPGVLSAD AGQVEHRRQM 120 NSADTDWGTE EGPGSLDFAV AAHQEDTFFL KDIKHTSTFR QSVQQQNCIY SPREKPCGNV 180 0 RAPCAPPRRE APLALSRPWR LSRSPAPSPR TPMAPFPTSD RELDAPGPPP GLRSSAAAPH 240 CLPAAPEAQK LFFLLPLYPD GSPPPKDILQ TLQHKAPGKR LHQESPGSFP IGLCNRTAEP 300 CIKGALGVAA EAAFHLQFSS E
Seq ID NO : 97 DNA sequence I D Nucleic Acid Accession ft : NM_003474 .2
Coding sequence : 37 . .3036
11 21 31 41 51
I 0 I I I I
CACTAACGCT CTTCCTAGTC CCCGGGCCAA CTCGGACAGT TTGCTCATTT ATTGCAACGG 60 TCAAGGCTGG CTTGTGCCAG AACGGCGCGC GCGCGACGCA CGCACACACA CGGGGGGAAA 120 CTTTTTTAAA AATGAAAGGC TAGAAGAGCT CAGCGGCGGC GCGGGCCGTG CGCGAGGGCT 180 CCGGAGCTGA CTCGCCGAGG CAGGAAATCC CTCCGGTCGC GACGCCCGGC CCCGCTCGGC 240 GCCCGCGTGG GATGGTGCAG CGCTCGCCGC CGGGCCCGAG AGCTGCTGCA CTGAAGGCCG 300 GCGACGATGG CAGCGCGCCC GCTGCCCGTG TCCCCCGCCC GCGCCCTCCT GCTCGCCCTG 360 GCCGGTGCTC TGCTCGCGCC CTGCGAGGCC CGAGGGGTGA GCTTATGGAA CGAAGGAAGA 420 GCTGATGAAG TTGTCAGTGC CTCTGTTCGG AGTGGGGACC TCTGGATCCC AGTGAAGAGC 480 TTCGACTCCA AGAATCATCC AGAAGTGCTG AATATTCGAC TACAACGGGA AAGCAAAGAA 540 CTGATCATAA ATCTGGAAAG AAATGAAGGT CTCATTGCCA GCAGTTTCAC GGAAACCCAC 600 TATCTGCAAG ACGGTACTGA TGTCTCCCTC GCTCGAAATT ACACGGTAAT TCTGGGTCAC 660 TGTTACTACC ATGGACATGT ACGGGGATAT TCTGATTCAG CAGTCAGTCT CAGCACGTGT 720 TCTGGTCTCA GGGGACTTAT TGTGTTTGAA AATGAAAGCT ATGTCTTAGA ACCAATGAAA 780 AGTGCAACCA ACAGATACAA ACTCTTCCCA GCGAAGAAGC TGAAAAGCGT CCGGGGATCA 840 TGTGGATCAC ATCACAACAC ACCAAACCTC GCTGCAAAGA ATGTGTTTCC ACCACCCTCT 900 CAGACATGGG CAAGAAGGCA TAAAAGAGAG ACCCTCAAGG CAACTAAGTA TGTGGAGCTG 960
GTGATCGTGG CAGACAACCG AGAGTTTCAG AGGCAAGGAA AAGATCTGGA AAAAGTTAAG 1020
CAGCGATTAA TAGAGATTGC TAATCACGTT GACAAGTTTT ACAGACCACT GAACATTCGG 1080
ATCGTGTTGG TAGGCGTGGA AGTGTGGAAT GACATGGACA AATGCTCTGT AAGTCAGGAC 1140
CCATTCACCA GCCTCCATGA ATTTCTGGAC TGGAGGAAGA TGAAGCTTCT ACCTCGCAAA 1200
TCCCATGACA ATGCGCAGCT TGTCAGTGGG GTTTATTTCC AAGGGACCAC CATCGGCATG 1260
GCCCCAATCA TGAGCATGTG CACGGCAGAC CAGTCTGGGG GAATTGTCAT GGACCATTCA 1320
GACAATCCCC TTGGTGCAGC CGTGACCCTG GCACATGAGC TGGGCCACAA TTTCGGGATG 1380
AATCATGACA CACTGGACAG GGGCTGTAGC TGTCAAATGG CGGTTGAGAA AGGAGGCTGC 1440
ATCATGAACG CTTCCACCGG GTACCCATTT CCCATGGTGT TCAGCAGTTG CAGCAGGAAG 1500
GACTTGGAGA CCAGCCTGGA GAAAGGAATG GGGGTGTGCC TGTTTAACCT GCCGGAAGTC 1560
AGGGAGTCTT TCGGGGGCCA GAAGTGTGGG AACAGATTTG TGGAAGAAGG AGAGGAGTGT 1620
GACTGTGGGG AGCCAGAGGA ATGTATGAAT CGCTGCTGCA ATGCCACCAC CTGTACCCTG 1680
AAGCCGGACG CTGTGTGCGC ACATGGGCTG TGCTGTGAAG AGTGCCAGCT GAAGCCTGCA 1740
GGAACAGCGT GCAGGGACTC CAGCAACTCC TGTGACCTCC CAGAGTTCTG CACAGGGGCC 1800
AGCCCTCACT GCCCAGCCAA CGTGTACCTG CACGATGGGC ACTCATGTCA GGATGTGGAC 1860
GGCTACTGCT ACAATGGCAT CTGCCAGACT CACGAGCAGC AGTGTGTCAC ACTCTGGGGA 1920
CCAGGTGCTA AACCTGCCCC TGGGATCTGC TTTGAGAGAG TCAATTCTGC AGGTGATCCT 1980
TATGGCAACT GTGGCAAAGT CTCGAAGAGT TCCTTTGCCA AATGCGAGAT GAGAGATGCT 2040
AAATGTGGAA AAATCCAGTG TCAAGGAGGT GCCAGCCGGC CAGTCATTGG TACCAATGCC 2100
GTTTCCATAG AAACAAACAT CCCCCTGCAG CAAGGAGGCC GGATTCTGTG CCGGGGGACC 2160
CACGTGTACT TGGGCGATGA CATGCCGGAC CCAGGGCTTG TGCTTGCAGG CACAAAGTGT 2220
GCAGATGGAA AAATCTGCCT GAATCGTCAA TGTCAAAATA TTAGTGTCTT TGGGGTTCAC 2280
GAGTGTGCAA TGCAGTGCCA CGGCAGAGGG GTGTGCAACA ACAGGAAGAA CTGCCACTGC 2340
GAGGCCCACT GGGCACCTCC CTTCTGTGAC AAGTTTGGCT TTGGAGGAAG CACAGACAGC 2400
GGCCCCATCC GGCAAGCAGA TAACCAAGGT TTAACCATAG GAATTCTGGT GACCATCCTG 2460
TGTCTTCTTG CTGCCGGATT TGTGGTTTAT CTCAAAAGGA AGACCTTGAT ACGACTGCTG 2520
TTTACAAATA AGAAGACCAC CATTGAAAAA CTAAGGTGTG TGCGCCCTTC CCGGCCACCC 2580
CGTGGCTTCC AACCCTGTCA GGCTCACCTC GGCCACCTTG GAAAAGGCCT GATGAGGAAG 2640
CCGCCAGATT CCTACCCACC GAAGGACAAT CCCAGGAGAT TGCTGCAGTG TCAGAATGTT 2700
GACATCAGCA GACCCCTCAA CGGCCTGAAT GTCCCTCAGC CCCAGTCAAC TCAGCGAGTG 2760
CTTCCTCCCC TCCACCGGGC CCCACGTGCA CCTAGCGTCC CTGCCAGACC CCTGCCAGCC 2820
AAGCCTGCAC TTAGGCAGGC CCAGGβGACC TGTAAGCCAA ACCCCCCTCA GAAGCCTCTG 2880
CCTGCAGATC CTCTGGCCAG AACAACTCGG CTCACTCATG CCTTGGCCAG GACCCCAGGA 2940
CAATGGGAGA CTGGGCTCCG CCTGGCACCC CTCAGACCTG CTCCACAATA TCCACACCAA 3000
GTGCCCAGAT CCACCCACAC CGCCTATATT AAGTGAGAAG CCGACACCTT TTTTCAACAG 3060
TGAAGACAGA AGTTTGCACT ATCTTTCAGC TCCAGTTGGA GTTTTTTGTA CCAACTTTTA 3120
GGATTTTTTT TAATGTTTAA AACATCATTA CTATAAGAAC TTTGAGCTAC TGCCGTCAGT 3180
GCTGTGCTGT GCTATGGTGC TCTGTCTACT TGCACAGGTA CTTGTAAATT ATTAATTTAT 3240
GCAGAATGTT GATTACAGTG CAGTGCGCTG TAGTAGGCAT TTTTACCATC ACTGAGTTTT 3300
CCATGGCAGG AAGGCTTGTT GTGCTTTTAG TATTTTAGTG AACTTGAAAT ATCCTGCTTG 3360
ATGGGATTCT GGACAGGATG TGTTTGCTTT CTGATCAAGG CCTTATTGGA AAGCAGTCCC 3420
CCAACTACCC CCAGCTGTGC TTATGGTACC AGATGCAGCT CAAGAGATCC CAAGTAGAAT 3480
CTCAGTTGAT TTTCTGGATT CCCCATCTCA GGCCAGAGCC AAGGGGCTTC AGGTCCAGGC 3540
TGTGTTTGGC TTTCAGGGAG GCCCTGTGCC CCTTGACAAC TGGCAGGCAG GCTCCCAGGG 3600
ACACCTGGGA GAAATCTGGC TTCTGGCCAG GAAGCTTTGG TGAGAACCTG GGTTGCAGAC 3660
AGGAATCTTA AGGTGTAGCC ACACCAGGAT AGAGACTGGA ACACTAGACA AGCCAGAACT 3720
TGACCCTGAG CTGACCAGCC GTGAGCATGT TTGGAAGGGG TCTGTAGTGT CACTCAAGGC 3780
GGTGCTTGAT AGAAATGCCA AGCACTTCTT TTTCTCGCTG TCCTTTCTAG AGCACTGCCA 3840 CCAGTAGGTT ATTTAGCTTG GGAAAGGTGG TGTTTCTGTA AGAAACCTAC TGCCCAGGCA 3900 CTGCAAACCG CCACCTCCCT ATACTGCTTG GAGCTGAGCA AATCACCACA AACTGTAATA 3960 CAATGATCCT GTATTCAGAC AGATGAGGAC TTTCCATGGG ACCACAACTA TTTTCAGATG 4020 TGAACCATTA ACCAGATCTA GTCAATCAAG TCTGTTTACT GCAAGGTTCA ACTTATTAAC 4080 AATTAGGCAG ACTCTTTATG CTTGCAAAAA CTACAACCAA TGGAATGTGA TGTTCATGGG 4140 TATAGTTCAT GTCTGCTATC ATTATTCGTA GATATTGGAC AAAGAACCTT CTCTATGGGG 4200 CATCCTCTTT TTCCAACTTG GCTGCAGGAA TCTTTAAAAG ATGCTTTTAA CAGAGTCTGA 4260 ACCTATTTCT TAAACACTTG CAACCTACCT GTTGAGCATC ACAGAATGTG ATAAGGAAAT 4320 CAACTTGCTT ATCAACTTCC TAAATATTAT GAGATGTGGC TTGGGCAGCA TCCCCTTGAA 4380 CTCTTCACTC TTCAAATGCC TGACTAGGGA GCCATGTTTC ACAAGGTCTT TAAAGTGACT 4440 AATGGCATGA GAAATACAAA AATACTCAGA TAAGGTAAAA TGCCATGATG CCTCTGTCTT 4500 CTGGACTGGT TTTCACATTA GAAGACAATT GACAACAGTT ACATAATTCA CTCTGAGTGT 4560 TTTATGAGAA AGCCTTCTTT TGGGGTCAAC AGTTTTCCTA TGCTTTGAAA CAGAAAAATA 4620 TGTACCAAGA ATCTTGGTTT GCCTTCCAGA AAACAAAACT GCATTTCACT TTCCCGGTGT 4680 TCCCCACTGT ATCTAGGCAA CATAGTATTC ATGACTATGG ATAAACTAAA CACGTGACAC 4740 AAACACACAC AAAAGGGAAC CCAGCTCTAA TACATTCCAA CTCGTATAGC ATGCATCTGT 4800 TTATTCTATA GTTATTAAGT TCTTTAAAAT GTAAAGCCAT GCTGGAAAAT AATACTGCTG 4860 AGATACATAC AGAATTACTG TAACTGATTA CACTTGGTAA TTGTACTAAA GCCAAACATA 4920 TATATACTAT TAAAAAGGTT TACAGAATTT TATGGTGCAT TACGTGGGCA TTGTCTTTTT 4980 AGATGCCCAA ATCCTTAGAT CTGGCATGTT AGCCCTTCCT CCAATTATAA GAGGATATGA 5040 ACCAAAAAAA AAAAAAAAAA AA
Seq ID NO: 98 Protein sequence Protein Accession #: NP 003465 11 21 31 41 51
I I I I I
MAARPLPVSP ARALLLALAG ALLAPCEARG VSLWNEGRAD EWSASVRSG DLWIPVKSFD 60 SKNHPEVLNI RLQRESKELI INLERNEGLI ASSFTETHYL QDGTDVSLAR NYTVILGHCY 120 YHGHVRGYSD SAVSLSTCSG LRG IVFENE SYVLEPMKSA TNRYKLFPAK KLKSVRGSCG 180 SHHNTPNLAA KNVFPPPSQT WARRHKRETL KATKYVELVI VADNREFQRQ GKDLEKVKQR 240 LIEIANHVDK FYRPLNIRIV LVGVEVWNDM DKCSVSQDPF TSLHEFLDWR KMKLLPRKSH 300 DNAQLVSGVY FQGTTIGMAP IMSMCTADQS GGIVMDHSDN PLGAAVTLAH ELGHNFGMNH 360 DTLDRGCSCQ MAVEKGGCIM NASTGYPFPM VFSSCSRKDL ETSLEKGMGV CLFNLPEVRE 420 SFGGQKCGNR FVEEGEECDC GEPEECMNRC CNATTCTLKP DAVCAHGLCC EDCQLKPAGT 480 ACRDSSNSCD LPEFCTGASP HCPANVYLHD GHSCQDVDGY CYNGICQTHE QQCVTLWGPG 540 AKPAPGICFE RVNSAGDPYG NCGKVSKSSF AKCEMRDAKC GKIQCQGGAS RPVIGTNAVS 600 IETNIPLQQG GRILCRGTHV YLGDDMPDPG LVLAGTKCAD GKICLNRQCQ NISVFGVHEC 660 AMQCHGRGVC NNRKNCHCEA HWAPPFCDKF GFGGSTDSGP IRQADNQGLT IGILVTILCL 720 LAAGFWYLK RKTLIRLLFT NKKTTIEKLR CVRPSRPPRG FQPCQAHLGH LGKGLMRKPP 780 DSYPPKDNPR RLLQCQNVDI ΞRPLNGLNVP QPQSTQRVLP PLHRAPRAPS VPARPLPAKP 840 ALRQAQGTCK PNPPQKPLPA DPLARTTRLT HALARTPGQW ETGLRLAPLR PAPQYPHQVP 900 RSTHTAYIK
Seq ID NO: 99 DNA sequence
Nucleic Acid Accession #: NM_003714
Coding sequence: 135..1043
11 21 31 41 51
I I I
GAGGAGGAGG GAAAAGGCGA GCAAAAAGGA AGAGTGGGAG GAGGAGGGGA AGCGGCGAAG 60 GAGGAAGAGG AGGAGGAGGA AGAGGGGAGC ACAAAGGATC CAGGTCTCCC GACGGGAGGT 120 TAATACCAAG AACCATGTGT GCCGAGCGGC TGGGCCAGTT CATGACCCTG GCTTTGGTGT 180 TGGCCACCTT TGACCCGGCG CGGGGGACCG ACGCCACCAA CCCACCCGAG GGTCCCCAAG 240 ACAGGAGCTC CCAGCAGAAA GGCCGCCTGT CCCTGCAGAA TACAGCGGAG ATCCAGCACT 300 GTTTGGTCAA CGCTGGCGAT GTGGGGTGTG GCGTGTTTGA ATGTTTCGAG AACAACTCTT 360 GTGAGATTCG GGGCTTACAT GGGATTTGCA TGACTTTTCT GCACAACGCT GGAAAATTTG 420 ATGCCCAGGG CAAGTCATTC ATCAAAGACG CCTTGAAATG TAAGGCCCAC GCTCTGCGGC 480 ACAGGTTCGG CTGCATAAGC CGGAAGTGCC CGGCCATCAG GGAAATGGTG TCCCAGTTGC 540 AGCGGGAATG CTACCTCAAG CACGACCTGT GCGCGGCTGC CCAGGAGAAC ACCCGGGTGA 600 TAGTGGAGAT GATCCATTTC AAGGACTTGC TGCTGCACGA ACCCTACGTG GACCTCGTGA 660 ACTTGCTGCT GACCTGTGGG GAGGAGGTGA AGGAGGCCAT CACCCACAGC GTGCAGGTTC 720 AGTGTGAGCA GAACTGGGGA AGCCTGTGCT CCATCTTGAG CTTCTGCACC TCGGCCATCC 780 AGAAGCCTCC CACGGCGCCC CCCGAGCGCC AGCCCCAGGT GGACAGAACC AAGCTCTCCA 840 GGGCCCACCA CGGGGAAGCA GGACATCACC TCCCAGAGCC CAGCAGTAGG GAGACTGGCC 900 GAGGTGCCAA GGGTGAGCGA GGTAGCAAGA GCCACCCAAA CGCCCATGCC CGAGGCAGAG 960 TCGGGGGCCT TGGGGCTCAG GGACCTTCCG GAAGCAGCGA GTGGGAAGAC GAACAGTCTG 1020 AGTATTCTGA TATCCGGAGG TGAAATGAAA GGCCTGGCCA CGAAATCTTT CCTCCACGCC 1080 GTCCATTTTC TTATCTATGG ACATTCCAAA ACATTTACCA TTAGAGAGGG GGGATGTCAC 1140 ACGCAGGATT CTGTGGGGAC TGTGGACTTC ATCGAGGTGT GTGTTCGCGG AACGGACAGG 1200 TGAGATGGAG ACCCCTGGGG CCGTGGGGTC TCAGGGGTGC CTGGTGAATT CTGCACTTAC 1260 ACGTACTCAA GGGAGCGCGC CCGCGTTATC CTCGTACCTT TGTCTTCTTT CCATCTGTGG 1320 AGTCAGTGGG TGTCGGCCGC TCTGTTGTGG GGGAGGTGAA CCAGGGAGGG GCAGGGCAAG 1380 GCAGGGCCCC CAGAGCTGGG CCACACAGTG GGTGCTGGGC CTCGCCCCGA AGCTTCTGGT 1440 GCAGCAGCCT CTGGTGCTGT CTCCGCGGAA GTCAGGGCGG CTGGATTCCA GGACAGGAGT 1500 GAATGTAAAA ATAAATATCG CTTAGAATGC AGGAGAAGGG TGGAGAβGAG GCAGGGGCCG 1560 AGGGGGTGCT TGGTGCCAAA CTGAAATTCA GTTTCTTGTG TGGGGCCTTG CGGTTCAGAG 1620 CTCTTGGCGA GGGTGGAGGG AGGAGTGTCA TTTCTATGTG TAATTTCTGA GCCATTGTAC 1680 TGTCTGGGCT GGGGGGGACA CTGTCCAAGG GAGTGGCCCC TATGAGTTTA TATTTTAACC 1740 ACTGCTTCAA ATCTCGATTT CACTTTTTTT ATTTATCCAG TTATATCTAC ATATCTGTCA 1800 TCTAAATAAA TGGCTTTCAA ACAAAGCAAC TGGGTCATTA AAACCAGCTC AAAGGGGGTT 1860 TAAAAAAAAA AAAACCAGCC CATCCTTTGA GGCTGATTTT TCTTTTTTTT AAGTTCTATT 1920 TTAAAAGCTA TCAAACAGCG ACATAGCCAT ACATCTGACT GCCTGACATG GACTCCTGCC 1980 CACTTGGGGG AAACCTTATA CCCAGAGGAA AATACACACC TGGGGAGTAC ATTTGACAAA 2040 TTTCCCTTAG GATTTCGTTA TCTCACCTTG ACCCTCAGCC AAGATTGGTA AAGCTGCGTC 2100 CTGGCGATTC CAGGAGACCC AGCTGGAAAC CTGGCTTCTC CATGTGAGGG GATGGGAAAG 2160 GAAAGAAGAG AATGAAGACT ACTTAGTAAT TCCCATCAGG AAATGCTGAC CTTTTACATA 2220 AAATCAAGGA GACTGCTGAA AATCTCTAAG GGACAGGATT TTCCAGATCC TAATTGGAAA 2280 TTTAGCAATA AGGAGAGGAG TCCAAGGGGA CAAATAAAGG CAGAGAGAGA GAGAGAGAGA 2340 GGGAGAGGAA GAAAAGAGAG AGAGAAAAGA GCCTCGTGCC
Seq ID NO: 100 Protein sequence Protein Accession it: NP 003705
11 21 31 41 51
MCAERLGQFM TLALVLATFD PARGTDATNP PEGPQDRSSQ QKGRLSLQNT AEIQHCLVNA 60 GDVGCGVFEC FENNSCEIRG LHGICMTFLH NAGKFDAQGK SFIKDALKCK AHALRHRFGC 120 ISRKCPAIRE MVSQLQRECY LKHDLCAAAQ ENTRVIVEMI HFKDLLLHEP YVDLVNLLLT 180 CGEEVKEAIT HSVQVQCEQN WGSLCSILSF CTSAIQKPPT APPERQPQVD RTKLSRAHHG 240 EAGHHLPEPS SRETGRGAKG ERGSKSHPNA HARGRVGGLG AQGPSGSSEW EDEQSEYSD1 300 RR
Seq ID NO: 101 DNA sequence Nucleic Acid Accession it: NM_ Coding sequence: 23..1489
11 21 AAGCCCAGCA GCCCCGGGGC GGATGGCTCC GGCCGCCTGG CTCCGCAGCG CGGCCGCGCG 60 CGCCCTCCTG CCCCCGATGC TGCTGCTGCT GCTCCAGCCG CCGCCGCTGC TGGCCCGGGC 120 TCTGCCGCCG GACGTCCACC ACCTCCATGC CGAGAGGAGG GGGCCACAGC CCTGGCATGC 180 AGCCCTGCCC AGTAGCCCGG CACCTGCCCC TGCCACGCAG GAAGCCCCCC GGCCTGCCAG 240 CAGCCTCAGG CCTCCCCGCT GTGGCGTGCC CGACCCATCT GATGGGCTGA GTGCCCGCAA 300 CCGACAGAAG AGGTTCGTGC TTTCTGGCGG GCGCTGGGAG AAGACGGACC TCACCTACAG 360 GATCCTTCGG TTCCCATGGC AGTTGGTGCA GGAGCAGGTG CGGCAGACGA TGGCAGAGGC 420 CCTAAAGGTA TGGAGCGATG TGACGCCACT CACCTTTACT GAGGTGCACG AGGGCCGTGC 480 TGACATCATG ATCGACTTCG CCAGGTACTG GCATGGGGAC GACCTGCCGT TTGATGGGCC 540 TGGGGGCATC CTGGCCCATG CCTTCTTCCC CAAGACTCAC CGAGAAGGGG ATGTCCACTT 600 CGACTATGAT GAGACCTGGA CTATCGGGGA TGACCAGGGC ACAGACCTGC TGCAGGTGGC 660 AGCCCATGAA TTTGGCCACG TGCTGGGGCT GCAGCACACA ACAGCAGCCA AGGCCCTGAT 720 GTCCGCCTTC TACACCTTTC GCTACCCACT GAGTCTCAGC CCAGATGACT GCAGGGGCGT 780 TCAACACCTA TATGGCCAGC CCTGGCCCAC TGTCACCTCC AGGACCCCAG CCCTGGGCCC 840 CCAGGCTGGG ATAGACACCA ATGAGATTGC ACCGCTGGAG CCAGACGCCC CGCCAGATGC 900 CTGTGAGGCC TCCTTTGACG CGGTCTCCAC CATCCGAGGC GAGCTCTTTT TCTTCAAAGC 960 GGGCTTTGTG TGGCGCCTCC GTGGGGGCCA GCTGCAGCCC GGCTACCCAG CATTGGCCTC 1020 TCGCCACTGG CAGGGACTGC CCAGCCCTGT GGACGCTGCC TTCGAGGATG CCCAGGGCCA 1080 CATTTGGTTC TTCCAAGGTG CTCAGTACTG GGTGTACGAC GGTGAAAAGC CAGTCCTGGG 1140 CCCCGCACCC CTCACCGAGC TGGGCCTGGT GAGGTTCCCG GTCCATGCTG CCTTGGTCTG 1200 GGGTCCCGAG AAGAACAAGA TCTACTTCTT CCGAGGCAGG GACTACTGGC GTTTCCACCC 1260 CAGCACCCGG CGTGTAGACA GTCCCGTGCC CCGCAGGGCC ACTGACTGGA GAGGGGTGCC 1320 CTCTGAGATC GACGCTGCCT TCCAGGATGC TGATGGCTAT GCCTACTTCC TGCGCGGCCG 1380 CCTCTACTGG AAGTTTGACC CTGTGAAGGT GAAGGCTCTG GAAGGCTTCC CCCGTCTCGT 1440 GGGTCCTGAC TTCTTTGGCT GTGCCGAGCC TGCCAACACT TTCCTCTGAC CATβGCTTGG 1500 ATGCCCTCAG GGGTGCTGAC CCCTGCCAGG CCACGAATAT CAGGCTAGAG ACCCATGGCC 1560 ATCTTTGTGG CTGTGGGCAC CAGGCATGGG ACTGAGCCCA TGTCTCCTGC AGGGGGATGG 1620 GGTGGGGTAC AACCACCATG ACAACTGCCG GGAGGGCCAC GCAGGTCGTG GTCACCTGCC 1680 AGCGACTGTC TCAGACTGGG CAGGGAGGCT TTGGCATGAC TTAAGAGGAA GGGCAGTCTT 1740 GGGACCCGCT ATGCAGGTCC TGGCAAACCT GGCTGCCCTG TCTCATCCCT GTCCCTCAGG laoo GTAGCACCAT GGCAGGACTG GGGGAACTGG AGTGTCCTTG CTGTATCCCT GTTGTGAGGT 1860 TCCTTCCAGG GGCTGGCACT GAAGCAAGGG TGCTGGGGCC CCATGGCCTT CAGCCCTGGC 1920 TGAGCAACTG GGCTGTAGGG CAGGGCCACT TCCTGAGGTC AGGTCTTGGT AGGTGCCTGC 1980 ATCTGTCTGC CTTCTGGCTG ACAATCCTGG AAATCTGTTC TCCAGAATCC AGGCCAAAAA 2040 GTTCACAGTC AAATGGGGAG GGGTATTCTT CATGCAGGAG ACCCCAGGCC CTGGAGβCTG 2100 CAACATACCT CAATCCTGTC CCAGGCCGGA TCCTCCTGAA GCCCTTTTCG CAGCACTGCT 2160 ATCCTCCAAA GCCATTGTAA ATGTGTGTAC AGTGTGTATA AACCTTCTTC TTCTTTTTTT 2220 TTTTTAAACT GAGGATTGTC ATTAAACACA GTTGTTTTCT
Seq ID NO: 102 Protein sequence Protein Accession ft: NP 005931
11 21 31 41 51
I I I I I
MAPAAWLRSA AARALLPPML LLLLQPPPLL ARALPPDVHH LHAERRGPQP WHAALPSSPA 60 PAPATQEAPR PASSLRPPRC GVPDPSDGLS ARNRQKRFVL SGGRWEKTDL TYRILRFPWQ 120 LVQEQVRQTM AEALKVWSDV TPLTFTEVHE GRADIMIDFA RYWHGDDLPF DGPGGILAHA 180 FFPKTHREGD VHFDYDETWT IGDDQGTDLL QVAAHEFGHV LGLQHTTAAK ALMSAFYTFR 240 YPLSLSPDDC RGVQHLYGQP WPTVTSRTPA LGPQAGIDTN EIAPLEPDAP PDACEASFDA 300 VSTIRGELFF FKAGFVWRLR GGQLQPGYPA LASRHWQGLP SPVDAAFEDA QGHIWFFQGA 360 QYWVYDGEKP VLGPAPLTEL GLVRFPVHAA LVWGPEKNKI YFFRGRDYWR FHPSTRRVDS 420 PVPRRATDWR GVPSEIDAAF QDADGYAYFL RGRLYWKFDP VKVKALEGFP RLVGPDFFGC 480 AEPANTFL
Seq ID NO: 103 DNA sequence
Nucleic Acid Accession ft: NM_033151.2
Coding sequence: 351..4499
60
120
Figure imgf000992_0001
180
TAAGGAGAGG AAAGAGCAGG CACCCAAACC TCTGCATGGC CCCAATATGC TCCCTGCAGG 240
GTAGTGCCCC CTCTTCTGGC TGCTCAAGGC GAGATCTAAG CTTCTTCTAA CTCCTGCTGT 300
CTTTTCATAT TCTCTGATTC TGGGAAACGA AGAATTGGCA GGAACTGAAA ATGACTAGGA 360
AGAGGACATA CTGGGTGCCC AACTCTTCTG GTGGCCTCGT GAATCGTGGC ATCGACATAG 420
GCGATGACAT GGTTTCAGGA CTTATTTATA AAACCTATAC TCTCCAAGAT GGCCCCTGGA 480
GTCAGCAAGA GAGAAATCCT GAGGCTCCAG GGAGGGCAGC TGTCCCACCG TGGGGGAAGT 540
ATGATGCTGC CTTGAGAACC ATGATTCCCT TCCGTCCCAA GCCGAGGTTT CCTGCCCCCC 600
AGCCCCTGGA CAATGCTGGC CTGTTCTCCT ACCTCACCGT GTCATGGCTC ACCCCGCTCA 660
TGATCCAAAG CTTACGGAGT CGCTTAGATG AGAACACCAT CCCTCCACTG TCAGTCCATG 720
ATGCCTCAGA CAAAAATGTC CAAAGGCTTC ACCGCCTTTG GGAAGAAGAA GTCTCAAGGC 780
GAGGGATTGA AAAAGCTTCA GTGCTTCTGG TGATGCTGAG GTTCCAGAGA ACAAGGTTGA 840
TTTTCGATGC ACTTCTGGGC ATCTGCTTCT GCATTGCCAG TGTACTCGGG CCAATATTGA 900
TTATACCAAA GATCCTGGAA TATTCAGAAG AGCAGTTGGG GAATGTTGTC CATGGAGTGG 960
GACTCTGCTT TGCCCTTTTT CTCTCCGAAT GTGTGAAGTC TCTGAGTTTC TCCTCCAGTT 1020
GGATCATCAA CCAACGCACA GCCATCAGGT TCCGAGCAGC TGTTTCCTCC TTTGCCTTTG 1080
AGAAGCTCAT CCAATTTAAG TCTGTAATAC ACATCACCTC AGGAGAGGCC ATCAGCTTCT 1140
TCACCGGTGA TGTAAACTAC CTGTTTGAAG GGGTGTGCTA TGGACCCCTA GTACTGATCA 1200
CCTGCGCATC GCTGGTCATC TGCAGCATTT CTTCCTACTT CATTATTGGA TACACTGCAT 1260
TTATTGCCAT CTTATGCTAT CTCCTGGTTT TCCCACTGGC GGTATTCATG ACAAGAATGG 1320
CTGTGAAGGC TCAGCATCAC ACATCTGAGG TCAGCGACCA GCGCATCCGT GTGACCAGTG 1380
AAGTTCTCAC TTGCATTAAG CTGATTAAAA TGTACACATG GGAGAAACCA TTTGCAAAAA 1440 TCATTGAAGA CCTAAGAAGG AAGGAAAGGA AACTATTGGA GAAGTGCGGG CTTGTCCAGA 1500
GCCTGACAAG TATAACCTTG TTCATCATCC CCACAGTGGC CACAGCGGTC TGGGTTCTCA 1560
TCCACACATC CTTAAAGCTG AAACTCACAG CGTCAATGGC CTTCAGCATG CTGGCCTCCT 1620
TGAATCTCCT TCGGCTGTCA GTGTTCTTTG TGCCTATTGC AGTCAAAGGT CTCACGAATT 1680
CCAAGTCTGC AGTGATGAGG TTCAAGAAGT TTTTCCTCCA GGAGAGCCCT GTTTTCTATG 1740
TCCAGACATT ACAAGACCCC AGCAAAGCTC TGGTCTTTGA GGAGGCCACC TTGTCATGGC 1800
AACAGACCTG TCCCGGGATC GTCAATGGGG CACTGGAGCT GGAGAGGAAC GGGCATGCTT 1860
CTGAGGGGAT GACCAGGCCT AGAGATGCCC TCGGGCCAGA GGAAGAAGGG AACAGCCTGG 1920
GCCCAGAGTT GCACAAGATC AACCTGGTGG TGTCCAAGGG GATGATGTTA GGGGTCTGCG 1980
GCAACACGGG GAGTGGTAAG AGCAGCCTGT TGTCAGCCAT CCTGGAGGAG ATGCACTTGC 2040
TCGAGGGCTC GGTGGGGGTG CAGGGAAGCC TGGCCTATGT CCCCCAGCAG GCCTGGATCG 2100
TCAGCGGGAA CATCAGGGAG AACATCCTCA TGGGAGGCGC ATATGACAAG GCCCGATACC 2160
TCCAGGTGCT CCACTGCTGC TCCCTGAATC GGGACCTGGA ACTTCTGCCC TTTGGAGACA 2220
TGACAGAGAT TGGAGAβCGG GGCCTCAACC TCTCTGGGGG GCAGAAACAG AGGATCAGCC 2280
TGGCCCGCGC CGTCTATTCC GACCGTCAGA TCTACCTGCT GGACGACCCC CTGTCTGCTG 2340
TGGACGCCCA CGTGGGGAAG CACATTTTTG AGGAGTGCAT TAAGAAGACA CTCAGGGGGA 2400
AGACGGTCGT CCTGGTGACC CACCAGCTGC AGTACTTAGA ATTTTGTGGC CAGATCATTT 2460
TGTTGGAAAA TGGGAAAATC TGTGAAAATG GAACTCACAG TGAGTTAATG CAGAAAAAGG 2520
GGAAATATGC CCAACTTATC CAGAAGATGC ACAAGGAAGC CACTTCGGAC ATGTTGCAGG 2580
ACACAGCAAA GATAGGAGAG AAGCCAAAGG TAGAAAGTCA GGCTCTGGCC ACCTCCCTGG 2640
AAGAGTCTCT CAACGGAAAT GCTGTGCCGG AGCATCAGCT CACACAGGAG GAGGAβATGG 2700
AAGAAGGCTC CTTGAGTTGG AGGGTCTACC ACCACTACAT CCAGGCAGCT GGAGGTTACA 2760
TGGTCTCTTG CATAATTTTC TTCTTCGTGG TGCTGATCGT CTTCTTAACG ATCTTCAGCT 2820
TCTGGTGGCT GAGCTACTGG TTGGAGCAGG GCTCGGGGAC CAATAGCAGC CGAGAGAGCA 2880
ATGGAACCAT GGCAGACCTG GGCAACATTG CAGACAATCC TCAACTGTCC TTCTACCAGC 2940
TGGTGTACGG GCTCAACGCC CTGCTCCTCA TCTGTGTGGG GGTCTGCTCC TCAGGGATTT 3000
TCACCAAAGT CACGAGGAAG GCATCCACGG CCCTGCACAA CAAGCTCTTC AACAAGGTTT 3060
TCCGCTGCCC CATGAGTTTC TTTGACACCA TCCCAATAGG CCGGCTTTTG AACTGCTTCG 3120
CAGGGGACTT GGAACAGCTG GACCAGCTCT TGCCCATCTT TTCAGAGCAG TTCCTGGTCC 3180
TGTCCTTAAT GGTGATCGCC GTCCTGTTGA TTGTCAGTGT GCTGTCTCCA TATATCCTGT 3240
TAATGGGAGC CATAATCATG GTTATTTGCT TCATTTATTA TATGATGTTC AAGAAGGCCA 3300
TCGGTGTGTT CAAGAGACTG GAGAACTATA GCCGGTCTCC TTTATTCTCC CACATCCTCA 3360
ATTCTCTGCA AGGCCTGAGC TCCATCCATG TCTATGGAAA AACTGAAGAC TTCATCAGCC 3420
AGTTTAAGAG GCTGACTGAT GCGCAGAATA ACTACCTGCT GTTGTTTCTA TCTTCCACAC 3480
GATGGATGGC ATTGAGGCTG GAGATCATGA CCAACCTTGT GACCTTGGCT GTTGCCCTGT 3540
TCGTGGCTTT TGGCATTTCC TCCACCCCCT ACTCCTTTAA AGTCATGGCT GTCAACATCG 3600
TGCTGCAGCT GGCGTCCAGC TTCCAGGCCA CTGCCCGGAT TGGCTTGGAG ACAGAGGCAC 3660
AGTTCACGGC TGTAGAGAGG ATACTGCAGT ACATGAAGAT GTGTGTCTCG GAAGCTCCTT 3720
TACACATGGA AGGCACAAGT TGTCCCCAGG GGTGGCCACA GCATGGGGAA ATCATATTTC 3780
AGGATTATCA CATGAAATAC AGAGACAACA CACCCACCGT GCTTCACGGC ATCAACCTGA 3840
CCATCCGCGG CCACGAAGTG GTGGGCATCG TGGGAAGGAC GGGCTCTGGG AAGTCCTCCT 3900
TGGGCATGGC TCTCTTCCGC CTGGTGGAGC CCATGGCAGG CCGGATTCTC ATTGACGGCG 3960
TGGACATTTG CAGCATCGGC CTGGAGGACT TGCGGTCCAA GCTCTCAGTG ATCCCTCAAG 4020
ATCCAGTGCT GCTCTCAGGA ACCATCAGAT TCAACCTAGA TCCCTTTGAC CGTCACACTG 4080
ACCAGCAGAT CTGGGATGCC TTGGAGAGGA CATTCCTGAC CAAGGCCATC TCAAAGTTCC 4140
CCAAAAAGCT GCATACAGAT GTGGTGGAAA ACGGTGGAAA CTTCTCTGTG GGGGAGAGGC 4200
AGCTGCTCTG CATTGCCAGG GCTGTGCTTC GCAACTCCAA GATCATCCTT ATCGATGAAG 4260
CCACAGCCTC CATTGACATG GAGACAGACA CCCTGATCCA GCGCACAATC CGTGAAGCCT 4320
TCCAGGGCTG CACCGTGCTC GTCATTGCCC ACCGTGTCAC CACTGTGCTG AACTGTGACC 4380
ACATCCTGGT TATGGGCAAT GGGAAGGTGG TAGAATTTGA TCGGCCGGAG GTACTGCGGA 4440
AGAAGCCTGG GTCATTGTTC GCAGCCCTCA TGGCCACAGC CACTTCTTCA CTGAGATAAG 4500
GAGATGTGGA GACTTCATGG AGGCTGGGAG CTGAGCTCAG AGGTTCACAC AGGTGCAGCT 4560
TCGAGGCCCA CAGTCTGCGA CCTTCTTGTT TGGAGATGAG AACTTCTCCT GGAAGCAGGG 4620
GTAAATGTAG GGGGGGTGGG GATTGCTGGA TGGAAACCCT GGAATAGGCT ACTTGATGGC 4680
TCTCAAGACC TTAGAACCCC AGAACCATCT AAGACATGGG ATTCAGTGAT CATGTGGTTC 4740
TCCTTTTAAC TTACATGCTG AATAATTTTA TAATAAGGTA AAAGCTTATA GTTTTCTGAT 4800
CTGTGTTAGA AβTGTTGCAA ATGCTGTACT GACTTTGTAA AATATAAAAC TAAGGAAAAC 4860
TC
Seq ID NO: 104 Protein sequence Protein Accession #: NP 149163.2
31
MTRKRTYWVP NSSGGLVNRG IDIGDDMVSG LIYKTYTLQD GPWSQQERNP EAPGRAAVPP 60
WGKYDAALRT MIPFRPKPRF PAPQPLDNAG LFSYLTVSWL TPLMIQSLRS RLDENTIPPL 120
SVHDASDKNV QRLHRLWEEE VSRRGIEKAS VLLVMLRFQR TRLIFDALLG ICFCIASVLG 180
PILIIPKILE YSEEQLGNW HGVGLCFALF LSECVKSLSF SSSWIINQRT AIRFRAAVSS 240
FAFEKLIQFK SVIHITSGEA ISFFTGDVNY LFEGVCYGPL VLITCASLVI CSISSYFIIG 300
YTAFIAILCY LLVFPLAVFM TRMAVKAQHH TSEVSDQRIR VTSEVLTCIK LIKMYTWEKP 360
FAKIIEDLRR KERKLLEKCG LVQSLTSITL FIIPTVATAV WVLIHTSLKL KLTASMAFSM 420
LASLNLLRLS VFFVPIAVKG LTNSKSAVMR FKKFFLQESP VFYVQTLQDP SKALVFEEAT 480
LSWQQTCPGI VNGALELERN GHASEGMTRP RDALGPEEEG NSLGPELHKI NLWSKGMML 540
GVCGNTGSGK SSLLSAILEE MHLLEGSVGV QGSLAYVPQQ AWIVSGNIRE NILMGGAYDK 600
ARYLQVLHCC SLNRDLELLP FGDMTEIGER GLNLSGGQKQ RISLARAVYS DRQIYLLDDP 660
LSAVDAHVGK HIFEECIKKT LRGKTWLVT HQLQYLEFCG QIILLENGKI CENGTHSELM 720
QKKGKYAQLI QKMHKEATSD MLQDTAKIAE KPKVESQALA TSLEESLNGN AVPEHQLTQE 780
EEMEEGSLSW RVYHHYIQAA GGYMVSCIIF FFWLIVFLT IFSFWWLSYW LEQGSGTNSS 840
RESNGTMADL GNIADNPQLS FYQLVYGLNA LLLICVGVCS SGIFTKVTRK ASTALHNKLF 900
NKVFRCPMSF FDTIPIGRLL NCFAGDLEQL DQLLPIFSEQ FLVLSLMVIA VLLIVSVLSP 960
YILLMGAIIM VICFIYYMMF KKAIGVFKRL ENYSRSPLFS HILNSLQGLS SIHVYGKTED 1020
FISQFKRLTD AQNNYLLLFL SSTRWMALRL EIMTNLVTLA VALFVAFGIS STPYSFKVMA 1080
VNIVLQLASS FQATARIGLE TEAQFTAVER ILQYMKMCVS EAPLHMEGTS CPQGWPQHGE 1140
IIFQDYHMKY RDNTPTVLHG INLTIRGHEV VGIVGRTGSG KSSLGMALFR LVEPMAGRIL 1200 IDGVDICSIG LEDLRSKLSV IPQDPVLLSG TIRFNLDPFD RHTDQQIWDA LERTFLTKAI 1260
SKFPKKLHTD WENGGNFSV GERQLLCIAR AVLRNSKIIL IDEATASIDM ETDTLIQRTI 1320
REAFQGCTVL VIAHRVTTVL NCDHILVMGN GKWEFDRPE VLRKKPGSLF AALMATATSS 1380 LR
Seq ID NO: 105 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..4043
1 11 21 31 41 51
I I I I I I
ATGACTAGGA AGAGGACATA CTGGGTGCCC AACTCTTCTG GTGGCCTCGT GAATCGTGGC 60
ATCGACATAG GCGATGACAT GGTTTCAGGA CTTATTTATA AAACCTATAC TCTCCAAGAT 120
GGCCCCTGGA GTCAGCAAGA GAGAAATCCT GAGGCTCCAG GGAGGGCAGC TGTCCCACCG 180
TGGGGGAAGT ATGATGCTGC CTTGAGAACC ATGATTCCCT TCCGTCCCAA GCCGAGGTTT 240
CCTGCCCCCC AGCCCCTGGA CAATGCTGGC CTGTTCTCCT ACCTCACCGT GTCATGGCTC 300
ACCCCGCTCA TGATCCAAAG CTTACGGAGT CGCTTAGATG AGAACACCAT CCCTCCACTG 360
TCAGTCCATG ATGCCTCAGA CAAAAATGTC CAAAGGCTTC ACCGCCTTTG GGAAGAAGAA 420
GTCTCAAGGC GAGGGATTGA AAAAGCTTCA GTGCTTCTGG TGATGCTGAG GTTCCAGAGA 480
ACAAGGTTGA TTTTCGATGC ACTTCTGGGC ATCTGCTTCT GCATTGCCAG TGTACTCGGG 540
CCAATATTGA TTATACCAAA GATCCTGGAA TATTCAGAAG AGCAGTTGGG GAATGTTGTC 600
CATGGAGTGG GACTCTGCTT TGCCCTTTTT CTCTCCGAAT GTGTGAAGTC TCTGAGTTTC 660
TCCTCCAGTT GGATCATCAA CCAACGCACA GCCATCAGGT TCCGAGCAGC TGTTTCCTCC 720
TTTGCCTTTG AGAAGCTCAT CCAATTTAAG TCTGTAATAC ACATCACCTC AGGAGAGGCC 780
ATCAGCTTCT TCACCGGTGA TGTAAACTAC CTGTTTGAAG GGGTGTGCTA TGGACCCCTA 840
GTACTGATCA CCTGCGCATC GCTGGTCATC TGCAGCATTT CTTCCTACTT CATTATTGGA 900
TACACTGCAT TTATTGCCAT CTTATGCTAT CTCCTGGTTT TCCCACTGGC GGTATTCATG 960
ACAAGAATGG CTGTGAAGGC TCAGCATCAC ACATCTGAGG TCAGCGACCA GCGCATCCGT 1020
GTGACCAGTG AAGTTCTCAC TTGCATTAAG CTGATTAAAA TGTACACATG GGAGAAACCA 1080
TTTGCAAAAA TCATTGAAGG TATGGAAAGT CTGACTTTCT GCTCCAAACC TGGTGATGGC 1140
ATGGCCTTCA GCATGCTGGC CTCCTTGAAT CTCCTTCGGC TGTCAGTGTT CTTTGTGCCT 1200
ATTGCAGTCA AAGGTCTCAC GAATTCCAAG TCTGCAGTGA TGAGGTTCAA GAAGTTTTTC 1260
CTCCAGGAGA GCCCTGTTTT CTATGTCCAG ACATTACAAG ACCCCAGCAA AGCTCTGGTC 1320
TTTGAGGAGG CCACCTTGTC ATGGCAACAG ACCTGTCCCG GGATCGTCAA TGGGGCACTG 1380
GAGCTGGAGA GGAACGGGCA TGCTTCTGAG GGGATGACCA GGCCTAGAGA TGCCCTCGGG 1440
CCAGAGGAAG AAGGGAACAG CCTGGGCCCA GAGTTGCACA AGATCAACCT GGTGGTGTCC 1500
AAGGGGATGA TGTTAGGGGT CTGCGGCAAC ACGGGGAGTG GTAAGAGCAG CCTGTTGTCA 1560
GCCATCCTGG AGGAGATGCA CTTGCTCGAG GGCTCGGTGG GGGTGCAGGG AAGCCTGGCC 1620
TATGTCCCCC AGCAGGCCTG GATCGTCAGC GGGAACATCA GGGAGAACAT CCTCATGGGA 1680
GGCGCATATG ACAAGGCCCG ATACCTCCAG GTGCTCCACT GCTGCTCCCT GAATCGGGAC 1740
CTGGAACTTC TGCCCTTTGG AGACATGACA GAGATTGGAG AGCGGGGCCT CAACCTCTCT 1800
GGGGGGCAGA AACAGAGGAT CAGCCTGGCC CGCGCCGTCT ATTCCGACCG TCAGATCTAC 1860
CTGCTGGACG ACCCCCTGTC TGCTGTGGAC GCCCACGTGG GGAAGCACAT TTTTGAGGAG 1920
TGCATTAAGA AGACACTCAG GGGGAAGACG GTCGTCCTGG TGACCCACCA GCTGCAGTAC 1980
TTAGAATTTT GTGGCCAGAT CATTTTGTTG GAAAATGGGA AAATCTGTGA AAATGGAACT 2040
CACAGTGAGT TAATGCAGAA AAAGGGGAAA TATGCCCAAC TTATCCAGAA GATGCACAAG 2100
GAAGCCACTT CGGACATGTT GCAGGACACA GCAAAGATAG CAGAGAAGCC AAAGGTAGAA 2160
AGTCAGGCTC TGGCCACCTC CCTGGAAGAG TCTCTCAACG GAAATGCTGT GCCGGAGCAT 2220
CAGCTCACAC AGGAGGAGGA GATGGAAGAA GGCTCCTTGA GTTGGAGGGT CTACCACCAC 2280
TACATCCAGG CAGCTGGAGG TTACATGGTC TCTTGCATAA TTTTCTTCTT CGTGGTGCTG 2340
ATCGTCTTCT TAACGATCTT CAGCTTCTGG TGGCTGAGCT ACTGGTTGGA GCAGGGCTCG 2400
GGGACCAATA GCAGCCGAGA GAGCAATGGA ACCATGGCAG ACCTGGGCAA CATTGCAGAC 2460
AATCCTCAAC TGTCCTTCTA CCAGCTGGTG TACGGGCTCA ACGCCCTGCT CCTCATCTGT 2520
GTGGGGGTCT GCTCCTCAGG GATTTTCACC AAAGTCACGA GGAAGGCATC CACGGCCCTG 2580
CACAACAAGC TCTTCAACAA GGTTTTCCGC TGCCCCATGA GTTTCTTTGA CACCATCCCA 2640
ATAGGCCGGC TTTTGAACTG CTTCGCAGGG GACTTGGAAC AGCTGGACCA GCTCTTGCCC 2700
ATCTTTTCAG AGCAGTTCCT GGTCCTGTCC TTAATGGTGA TCGCCGTCCT GTTGATTGTC 2760
AGTGTGCTGT CTCCATATAT CCTGTTAATG GGAGCCATAA TCATGGTTAT TTGCTTCATT 2820
TATTATATGA TGTTCAAGAA GGCCATCGGT GTGTTCAAGA GACTGGAGAA CTATAGCCGG 2880
TCTCCTTTAT TCTCCCACAT CCTCAATTCT CTGCAAGGCC TGAGCTCCAT CCATGTCTAT 2940
GGAAAAACTG AAGACTTCAT CAGCCAGTTT AAGAGGCTGA CTGATGCGCA GAATAACTAC 3000
CTGCTGTTGT TTCTATCTTC CACACGATGG ATGGCATTGA GGCTGGAGAT CATGACCAAC 3060
CTTGTGACCT TGGCTGTTGC CCTGTTCGTG GCTTTTGGCA TTTCCTCCAC CCCCTACTCC 3120
TTTAAAGTCA TGGCTGTCAA CATCGTGCTG CAGCTGGCGT CCAGCTTCCA GGCCACTGCC 3180
CGGATTGGCT TGGAβACAGA GGCACAGTTC ACGGCTGTAG AGAGGATACT GCAGTACATG 3240
AAGATGTGTG TCTCGGAAGC TCCTTTACAC ATGGAAGGCA CAAGTTGTCC CCAGGGGTGG 3300
CCACAGCATG GGGAAATCAT ATTTCAGGAT TATCACATGA AATACAGAGA CAACACACCC 3360
ACCGTGCTTC ACGGCATCAA CCTGACCATC CGCGGCCACG AAGTGGTGGG CATCGTGGGA 3420
AGGACGGGCT CTGGGAAGTC CTCCTTGGGC ATGGCTCTCT TCCGCCTGGT GGAGCCCATG 3480
GCAGGCCGGA TTCTCATTGA CGGCGTGGAC ATTTGCAGCA TCGGCCTGGA GGACTTGCGG 3540
TCCAAGCTCT CAGTGATCCC TCAAGATCCA GTGCTGCTCT CAGGAACCAT CAGATTCAAC 3600
CTAGATCCCT TTGACCGTCA CACTGACCAG CAGATCTGGG ATGCCTTGGA GAGGACATTC 3660
CTGACCAAGG CCATCTCAAA GTTCCCCAAA AAGCTGCATA CAGATGTGGT GGAAAACGGT 3720
GGAAACTTCT CTGTGGGGGA GAGGCAGCTG CTCTGCATTG CCAGGGCTGT GCTTCGCAAC 3780
TCCAAGATCA TCCTTATCGA TGAAGCCACA GCCTCCATTG ACATGGAGAC AGACACCCTG 3840
ATCCAGCGCA CAA.TCCGTGA AGCCTTCCAG GGCTGCACCG TGCTCGTCAT TGCCCACCGT 3900
GTCACCACTG TGCTGAACTG TGACCACATC CTGGTTATGG GCAATGGGAA GGTGGTAGAA 3960
TTTGATCGGC CGGAGGTACT GCGGAAGAAG CCTGGGTCAT TGTTCGCAGC CCTCATGGCC 4020 ACAGCCACTT CTTCACTGAG ATAA
Seq ID NO: 106 Protem sequence Protein Accession ft: Eos sequence 11 21 31 41 51
I I I I
MTRKRTYWVP I
NSSGGLVNRG IDIGDDMVSG LIYKTYTLQD GPWSQQERNP EAPGRAAVPP 60 WGKYDAALRT MIPFRPKPRF PAPQPLDNAG LFSYLTVSWL TPLMIQSLRS RLDENTIPPL- 120 SVHDASDKNV QRLHRLWEEE VSRRGIEKAS VLLVMLRFQR TRLIFDALLG ICFCIASVLG 180 PILIIPKILE YSEEQLGNW HGVGLCFALF LSECVKSLΞF SSSWIINQRT AIRFRAAVSS 240 FAFEKLIQFK SVIHITSGEA ISFFTGDVNY LFEGVCYGPL VLITCASLVI CSISSYFIIG 300 YTAFIAILCY LLVFPLAVFM TRMAVKAQHH TSEVSDQRIR VTSEVLTCIK LIKMYTWEKP 360 FAKIIEGMES LTFCSKPGDG MAFSMLASLN LLRLSVFFVP IAVKGLTNSK SAVMRFKKFF 420 0 LQESPVFYVQ TLQDPSKALV FEEATLSWQQ TCPGIVNGAL ELERNGHASE GMTRPRDALG 480 PEEEGNSLGP ELHKINLWS KGMMLGVCGN TGSGKSSLLS AILEEMHLLE GSVGVQGSLA 540 YVPQQAWIVS GNIRENILMG GAYDKARYLQ VLHCCSLNRD LELLPFGDMT EIGERGLNLS 600 GGQKQRISLA RAVYSDRQI LLDDPLSAVD AHVGKHIFEE CIKKTLRGKT LVTHQLQY 660 LEFCGQIILL ENGKICENGT HSELMQKKGK YAQLIQKMHK EATSDMLQDT AKIAEKPKVE 720 5 SQALATSLEE SLNGNAVPEH QLTQEEEMEE GSLSWRVYHH YIQAAGGYMV SCIIFFFWL 780 IVFLTIFSFW WLSYWLEQGS GTNSSRESNG TMADLGNIAD NPQLSFYQLV YGLNALLLIC 840 VGVCSSGIFT KVTRKASTAL HNKLFNKVFR CPMSFFDTIP IGRLLNCFAG DLEQLDQLLP 900 IFSEQFLVLS LMVIAVLLIV SVLSPYILLM GAIIMVICFI YYMMFKKAIG VFKRLENYSR 960 SPLFSHILNS LQGLSSIHVY GKTEDFISQF KRLTDAQNNY LLLFLSSTRW MALRLEIMTN 1020 0 LVTLAVALFV AFGISSTPYS FKVMAVNIVL QLASSFQATA RIGLETEAQF TAVERILQYM 1080 KMCVSEAPLH MEGTSCPQGW PQHGEIIFQD YHMKYRDNTP TVLHGINLTI RGHEWGIVG 1140 RTGSGKSSLG MALFRLVEPM AβRILIDGVD ICSIGLEDLR SKLSVIPQDP VLLSGTIRFN 1200 LDPFDRHTDQ QIWDALERTF LTKAISKFPK KLHTDWENG GNFSVGERQL LCIARAVLRN 1260 SKIILIDEAT ASIDMETDTL IQRTIREAFQ GCTVLVIAHR VTTVLNCDHI LVMGNGKWE 1320 5 FDRPEVLRKK PGSLFAALMA TATSSLR
Seq ID NO: 107 DNA sequence Nucleic Acid Accession if: NM_024022 Coding sequence: 202..1563 0
11 21 31 41 51
ACCGGGCACC GGACGGCTCG GGTACTTTCG TTCTTAATTA GGTCATGCCC GTβTGAGCCA 60
GGAAAGGGCT GTGTTTATGG GAAGCCAGTA ACACTGTGGC CTACTATCTC TTCCGTGGTG 120 5 CCATCTACAT TTTTGGGACT CGGGAATTAT GAGGTAGAGG TGGAGGCGGA GCCGGATGTC 180
AGAGGTCCTG AAATAGTCAC CATGGGGGAA AATGATCCGC CTGCTGTTGA AGCCCCCTTC 240
TCATTCCGAT CGCTTTTTGG CCTTGATGAT TTGAAAATAA GTCCTGTTGC ACCAGATGCA 300
GATGCTGTTG CTGCACAGAT CCTGTCACTG CTGCCATTGA AGTTTTTTCC AATCATCGTC 360
ATTGGGATCA TTGCATTGAT ATTAGCACTG GCCATTGGTC TGGGCATCCA CTTCGACTGC 420 0 TCAGGGAAGT ACAGATGTCG CTCATCCTTT AAGTGTATCG AGCTGATAGC TCGATGTGAC 480
GGAGTCTCGG ATTGCAAAGA CGGGGAGGAC GAGTACCGCT GTGTCCGGGT GGGTGGTCAG 540
AATGCCGTGC TCCAGGTGTT CACAGCTGCT TCGTGGAAGA CCATGTGCTC CGATGACTGG 600
AAGGGTCACT ACGCAAATGT TGCCTGTGCC CAACTGGGTT TCCCAAGCTA TGTGAGTTCA 660
GATAACCTCA GAGTGAGCTC GCTGGAGGGG CAGTTCCGGG AGGAGTTTGT GTCCATCGAT 720 5 CACCTCTTGC CAGATGACAA GGTGACTGCA TTACACCACT CAGTATATGT GAGGGAGGGA 780
TGTGCCTCTG GCCACGTGGT TACCTTGCAG TGCACAGCCT GTGGTCATAG AAGGGGCTAC 840
AGCTCACGCA TCGTGGGTGG AAACATGTCC TTGCTCTCGC AGTGGCCCTG GCAGGCCAGC 900
CTTCAGTTCC AGGGCTACCA CCTGTGCGGG GGCTCTGTCA TCACGCCCCT GTGGATCATC 960
ACTGCTGCAC ACTGTGTTTA TGACTTGTAC CTCCCCAAGT CATGGACCAT CCAGGTGGGT 1020 0 CTAGTTTCCC TGTTGGACAA TCCAGCCCCA TCCCACTTGG TGGAGAAGAT TGTCTACCAC 1080
AGCAAGTACA AGCCAAAGAG GCTGGGCAAT GACATCGCCC TTATGAAGCT GGCCGGGCCA 1140
CTCACGTTCA ATGAAATGAT CCAGCCTGTG TGCCTGCCCA ACTCTGAAGA GAACTTCCCC 1200
GATGGAAAAG TGTGCTGGAC GTCAGGATGG GGGGCCAGAG AGGATGGAGG TGACGCCTCC 1260
CCTGTCCTGA ACCACGCGGC CGTCCCTTTG ATTTCCAACA AGATCTGCAA CCACAGGGAC 1320 5 GTGTACGGTG GCATCATCTC CCCCTCCATG CTCTGCGCGG GCTACCTGAC GGGTGGCGTG 1380
GACAGCTGCC AGGGGGACAG CGGGGGGCCC CTGGTGTGTC AAGAGAGGAG GCTGTGGAAG 1440
TTAGTGGGAG CGACCAGCTT TGGCATCGGC TGCGCAGAGG TGAACAAGCC TGGGGTGTAC 1500
ACCCGTGTCA CCTCCTTCCT GGACTGGATC CACGAGCAGA TGGAGAGAGA CCTAAAAACC 1560
TGAAGAGGAA GGGGACAAGT AGCCACCTGA GTTCCTGAGG TGATGAAGAC AGCCCGATCC 1620 0 TCCCCTGGAC TCCCGTGTAG GAACCTGCAC ACGAGCAGAC ACCCTTGGAG CTCTGAGTTC 1680
CGGCACCAGT AGCAGGCCCG AAAGAGGCAC CCTTCCATCT GATTCCAGCA CAACCTTCAA 1740
GCTGCTTTTT GTTTTTTGTT TTTTTGAGGT GGAGTCTCGC TCTGTTGCCC AGGCTGGAGT 1800
GCAGTGGCGA AATCCCTGCT CACTGCAGCC TCCGCTTCCC TGGTTCAAGC GATTCTCTTG 1860
CCTCAGCTTC CCCAGTAGCT GGGACCACAG GTGCCCGCCA CCACACCCAA CTAATTTTTG 1920 5 TATTTTTAGT AGAGACAGGG TTTCACCATG TTGGCCAGGC TGCTCTCAAA CCCCTGACCT 1980
CAAATGATGT GCCTGCTTCA GCCTCCCACA GTGCTGGGAT TACAβGCATG GGCCACCACC 2040
CCTAGCCTCA CGCTCCTTTC TGATCTTCAC TAAGAACAAA AGAAGCAGCA ACTTGCAAGG 2100
GCGGCCTTTC CCACTGGTCC ATCTGGTTTT CTCTCCAGGG GTCTTGCAAA ATTCCTGACG 2160
AGATAAGCAG TTATGTGACC TCACGTGCAA AGCCACCAAC AGCCACTCAG AAAAGACGCA 2220 0 CCAGCCCAGA AGTGCAGAAC TGCAGTCACT GCACGTTTTC ATCTCTAGGG ACCAGAACCA 2280
AACCCACCCT TTCTACTTCC AAGACTTATT TTCACATGTG GGGAGGTTAA TCTAGGAATG 2340
ACTCGTTTAA GGCCTATTTT CATGATTTCT TTGTAGCATT TGGTGCTTGA CGTATTATTG 2400
TCCTTTGATT CCAAATAATA TGTTTCCTTC CCTCAAAAAA AAAAAAAAAA AAAAAAAAAA 2460
AAAAA 5
Seq ID NO: 108 Protein sequence Protein Accession ft: NP 076927
-._ 1 11 21 31 41 51
80 i i i i i i
MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP IIVIGIIALI 60 LALAIGLGIH FDCSGKYRCR SSFKCIELIA RCDGVSDCKD GEDEYRCVRV GGQNAVLQVF 120 TAASWKTMCS DDWKGHYANV ACAQLGFPSY VSSDNLRVSS LEGQFREEFV SIDHLLPDDK 180 VTALHHSVYV REGCASGHW TLQCTACGHR RGYSSRIVGG NMSLLSQWPW QASLQFQGYH 240 LCGGSVITPL WIITAAHCVY DLYLPKSWTI QVGLVSLLDN PAPSHLVEKI VYHSKYKPKR 300
LGNDIALMKL AGPLTFNEMI QPVCLPNSEE NFPDGKVCWT SGWGATEDGG DASPVLNHAA 360
VPLISNKICN HRDVYGGIIS PSMLCAGYLT GGVDSCQGDS GGPLVCQERR LWKLVGATSF 420 GIGCAEVNKP GVYTRVTSFL DWIHEQMERD LKT
Seq ID NO: 109 DNA sequence
Nucleic Acid Accession it: NM_000493.2
Coding sequence: 97..2139
1 11 21 31 41 51
I I I I I I
CACCTTCTGC ACTGCTCATC TGGGCAGAGG AAGCTTCAGA AAGCTGCCAA GGCACCATCT 60
CCAGGAACTC CCAGCACGCA GAATCCATCT GAGAATATGC TGCCACAAAT ACCCTTTTTG 120
CTGCTAGTAT CCTTGAACTT GGTTCATGGA GTGTTTTACG CTGAACGATA CCAAATGCCC 180
ACAGGCATAA AAGGCCCACT ACCCAACACC AAGACACAGT TCTTCATTCC CTACACCATA 240
AAGAGTAAAG GTATAGCAGT AAGAGGAGAG CAAGGTACTC CTGGTCCACC AGGCCCTGCT 300
GGACCTCGAG GGCACCCAGG TCCTTGTGGA CCACCAGGAA AACCAGGCTA CGGAAGTCCT 360
GGACTCCAAG GAGAGCCAGG GTTGCCAGGA CCACCGGGAC CATCAGCTGT AGGGAAACCA 420
GGTGTGCCAG GACTCCCAGG AAAACCAGGA GAGAGAGGAC CATATGGACC AAAAGGAGAT 480
GTTGGACCAG CTGGCCTACC AGGACCCCGG GGCCCACCAβ GACCACCTGG AATCCCTGGA 540
CCGGCTGGAA TTTCTGTGCC AGGAAAACCT GGACAACAGG GACCCACAGG AGCCCCAGGA 600
CCCAGGGGCT TTCCTGGAGA AAAGGGTGCA CCAGGAGTCC CTGGTATGAA TGGACAGAAA 660
GGGGAAATGG GATATGGTGC TCCTGGTCGT CCAGGTGAGA GGGGTCTTCC AGGCCCTCAG 720
GGTCCCACAG GACCATCTGG CCCTCCTGGA GTGGGAAAAA GAGGTGAAAA TGGGGTTCCA 780
GGACAGCCAG GCATCAAAGG TGATAGAGGT TTTCCGGGAG AAATGGGACC AATTGGCCCA 840
CCAGGTCCCC AAGGCCCTCC TGGGGAACGA GGGCCAGAAG GCATTGGAAA GCCAGGAGCT 900
GCTGGAGCCC CAGGCCAGCC AGGGATTCCA GGAACAAAAG GTCTCCCTGG GGCTCCAGGA 960
ATAGCTGGGC CCCCAGGGCC TCCTGGCTTT GGGAAACCAG GCTTGCCAGG CCTGAAGGGA 1020
GAAAGAGGAC CTGCTGGCCT TCCTGGGGGT CCAGGTGCCA AAGGGGAACA AGGGCCAGCA 1080
GGTCTTCCTG GGAAGCCAGG TCTGACTGGA CCCCCTGGGA ATATGGGACC CCAAGGACCA 1140
AAAGGCATCC CGGGTAGCCA TGGTCTCCCA GGCCCTAAAG GTGAGACAGG GCCAGCTGGG 1200
CCTGCAGGAT ACCCTGGGGC TAAGGGTGAA AGGGGTTCCC CTGGGTCAGA TGGAAAACCA 1260
GGGTACCCAG GAAAACCAGG TCTCGATGGT CCTAAGGGTA ACCCAGGGTT ACCAGGTCCA 1320
AAAGGTGATC CTGGAGTTGG AGGACCTCCT GGTCTCCCAG GCCCTGTGGG CCCAGCAGGA 1380
GCAAAGGGAA TGCCCGGACA CAATGGAGAG GCTGGCCCAA GAGGTGCCCC TGGAATACCA 1440
GGTACTAGAG GCCCTATTGG GCCACCAGGC ATTCCAGGAT TCCCTGGGTC TAAAGGGGAT 1500
CCAGGAAGTC CCGGTCCTCC TGGCCCAGCT GGCATAGCAA CTAAGGGCCT CAATGGACCC 1560
ACCGGGCCAC CAGGGCCTCC AGGTCCAAGA GGCCACTCTG GAGAGCCTGG TCTTCCAGGG 1620
CCCCCTGGGC CTCCAGGCCC ACCAGGTCAA GCAGTCATGC CTGAGGGTTT TATAAAGGCA 1680
GGCCAAAGGC CCAGTCTTTC TGGGACCCCT CTTGTTAGTG CCAACCAGGG GGTAACAGGA 1740
ATGCCTGTGT CTGCTTTTAC TGTTATTCTC TCCAAAGCTT ACCCAGCAAT AGGAACTCCC 1800
ATACCATTTG ATAAAATTTT GTATAACAGG CAACAGCATT ATGACCCAAG GACTGGAATC 1860
TTTACTTGTC AGATACCAGG AATATACTAT TTTTCATACC ACGTGCATGT GAAAGGGACT 1920
CATGTTTGGG TAGGCCTGTA TAAGAATGGC ACCCCTGTAA TGTACACCTA TGATGAATAC 1980
ACCAAAGGCT ACCTGGATCA GGCTTCAGGG AGTGCCATCA TCGATCTCAC AGAAAATGAC 2040
CAGGTGTGGC TCCAGCTTCC CAATGCCGAG TCAAATGGCC TATACTCCTC TGAGTATGTC 2100
CACTCCTCTT TCTCAGGATT CCTAGTGGCT CCAATGTGAG TACACCCCAC AGAGCTAATC 2160
TAAATCTTGT GCTAGAAAAA GCATTCTCTA ACTCTACCCC ACCCTACAAA ATGCATATGG 2220
AGGTAGGCTG AAAAGAATGT AATTTTTATT TTCTGAAATA CAGATTTGAG CTATCAGACC 2280
AACAAACCTT CCCCCTGAAA AGTGAGCAGC AACGTAAAAA CGTATGTGAA GCCTCTCTTG 2340
AATTTCTAGT TAGCAATCTT AAGGCTCTTT AAGGTTTTCT CCAATATTAA AAAATATCAC 2400
CAAAGAAGTC CTGCTATGTT AAAAACAAAC AACAAAAAAC AAAGCAACAA AAAAAAAAAT 2460
TAAAAAAAAA AACAGAAATA GAGCTCTAAG TTATGTGAAA TTTGATTTGA GAAACTCGGC 2520
ATTTCCTTTT TAAAAAAGCC TGTTTCTAAC TATGAATATG AGAACTTCTA GGAAACATCC 2580
AGGAGGTATC ATATAACTTT GTAGAACTTA AATACTTGAA TATTCAAATT TAAAAGACAC 2640
TGTATCCCCT AAAATATTTC TGATGGTGCA CTACTCTGAG GCCTGTATGG CCCCTTTCAT 2700
CAATATCTAT TCAAATATAC AGGTGCATAT ATACTTGTTA AAGCTCTTAT ATAAAAAAGC 2760
CCCAAAATAT TGAAGTTCAT CTGAAATGCA AGGTGCTTTC ATCAATGAAC CTTTTCAAAA 2820
CTTTTCTATG ATTGCAGAGA AGCTTTTTAT ATACCCAGCA TAACTTGGAA ACAGGTATCT 2880
GACCTATTCT TATTTAGTTA ACACAAGTGT GATTAATTTG ATTTCTTTAA TTCCTTATTG 2940
AATCTTATGT GATATGATTT TCTGGATTTA CAGAACATTA GCACATGTAC CTTGTGCCTC 3000
CCATTCAAGT GAAGTTATAA TTTACACTGA GGGTTTCAAA ATTCGACTAG AAGTGGAGAT 3060
ATATTATTTA TTTATGCACT GTACTGTATT TTTATATTGC TGTTTAAAAC TTTTAAGCTG 3120
TGCCTCACTT ATTAAAGCAC AAAATGTTTT ACCTACTCCT TATTTACGAC ACAATAAAAT 3180
AACATCAATA GATTTTTAGG CTGAATTAAT TTGAAAGCAG CAATTTGCTG TTCTCAACCA 3240
TTCTTTCAAG GCTTTTCATT CGACACAATA AAATAACATC AATAG
Seq ID NO: 110 Protein sequence rotein Accession #: NP_000484.2
11 21 31 41 51
I I I I I
MLPQIPFLLL VSLNLVHGVF YAERYQMPTG IKGPLPNTKT QFFIPYTIKS KGIAVRGEQG 60 TPGPPGPAGP RGHPGPSGPP GKPGYGSPGL QGEPGLPGPP GPSAVGKPGV PGLPGKPGER 120 GPYGPKGDVG PAGLPGPRGP PGPPGIPGPA GISVPGKPGQ QGPTGAPGPR GFPGEKGAPG 180 VPGMNGQKGE MGYGAPGRPG ERGLPGPQGP TGPSGPPGVG KRGENGVPGQ PGIKGDRGFP 240 GEMGPIGPPG PQGPPGERGP EGIGKPGAAG APGQPGIPGT KGLPGAPGIA GPPGPPGFGK 300 PGLPGLKGER GPAGLPGGPG AKGEQGPAGL PGKPGLTGPP GNMGPQGPKG IPGSHGLPGP 360 KGETGPAGPA GYPGAKGERG SPGSDGKPGY PGKPGLDGPK GNPGLPGPKG DPGVGGPPGL 420 PGPVGPAGAK GMPGHNGEAG PRGAPGIPGT RGPIGPPGIP GFPGSKGDPG SPGPPGPAGI 480 ATKGLNGPTG PPGPPGPRGH SGEPGLPGPP GPPGPPGQAV MPEGFIKAGQ RPSLSGTPLV 540 SANQGVTGMP VSAFTVILSK AYPAIGTPIP FDKILYNRQQ HYDPRTGIFT CQIPGIYYFS 600 YHVHVKGTHV WVGLYKNGTP VMYTYDEYTK GYLDQASGSA IIDLTENDQV WLQLPNAESN 660 GLYSSEYVHS SFSGFLVAPM Seq ID NO: 111 DNA sequence Nucleic Acid Accession tt: NM_000949 Coding sequence: 285..2153
11 21 31 51
GGAGGCTGAA ATCCCCAGAC GCCGGTTTTC TGGGCTGGGC TTTCTGCTTA CTCACTCCTT 60
CTCCCTCTTT CTGGATTTTA CCGACCGTTC GCGAAACAGC TTTCCACACA ATGGAGCTTC 120
ATGTCCTCGT GCAGGAAGTA CTCATCGACT GATGTGGCAG ACTTTGCTCC CTGACAAAAC 180
TAAAGAACTC TCCTATTCAT GGAGGCGAAC ACTGAGGATG CTTTCCACAT GAACGCTGAA 240
GTGAACTTCT GATACATTTC CTGCAGCAAG AGAAGGCAGC CAACATGAAG GAAAATGTGG 300
CATCTGCAAC CGTTTTCACT CTGCTACTTT TTCTCAACAC CTGCCTTCTG AATGGACAGT 360
TACCTCCTGG AAAACCTGAG ATCTTTAAAT GTCGTTCTCC CAATAAGGAA ACATTCACCT 420
GCTGGTGGAG GCCTGGGACA GATGGAGGAC TTCCTACCAA TTATTCACTG ACTTACCACA 480
GGGAAGGAGA GACACTCATG CATGAATGTC CAGACTACAT AACCGGTGGC CCCAACTCCT 540
GCCACTTTGG CAAGCAGTAC ACCTCCATGT GGAGGACATA CATCATGATG GTCAATGCCA 600
CTAACCAGAT GGGAAGCAGT TTCTCGGATG AACTTTATGT GGACGTGACT TACATAGTTC 660
AGCCAGACCC TCCTTTGGAG CTGGCTGTGG AAGTAAAACA GCCAGAAGAC AGAAAACCCT 720
ACCTGTGGAT TAAATGGTCT CCACCTACCC TGATTGACTT AAAAACTGGT TGGTTCACGC 780
TCCTGTATGA AATTCGATTA AAACCCGAGA AAGCAGCTGA GTGGGAGATC CATTTTGCTG 840
GGCAGCAAAC AGAGTTTAAG ATTCTCAGCC TACATCCAGG ACAGAAATAC CTTGTCCAGG 900
TTCGCTGCAA ACCAGACCAT GGATACTGGA GTGCATGGAG TCCAGCGACC TTCATTCAGA 960
TACCTAGTGA CTTCACCATG AATGATACAA CCGTGTGGAT CTCTGTGGCT GTCCTTTCTG 1020
CTGTCATCTG TTTGATTATT GTCTGGGCAG TGGCTTTGAA GGGCTATAGC ATGGTGACCT 1080
GCATCTTTCC GCCAGTTCCT GGGCCAAAAA TAAAAGGATT TGATGCTCAT CTGTTGGAGA 1140
AGGGCAAGTC TGAAGAACTA CTGAGTGCCT TGGGATGCCA AGACTTTCCT CCCACTTCTG 1200
ACTATGAGGA CTTGCTGGTG GAGTATTTAG AAGTAGATGA TAGTGAGGAC CAGCATCTAA 1260
TGTCAGTCCA TTCAAAAGAA CACCCAAGTC AAGGTATGAA ACCCACATAC CTGGATCCTG 1320
ACACTGACTC AGGCCGGGGG AGCTGTGACA GCCCTTCCCT TTTGTCTGAA AAGTGTGAGG 1380
AACCCCAGGC CAATCCCTCC ACATTCTATG ATCCTGAGGT CATTGAGAAG CCAGAGAATC 1440
CTGAAACAAC CCACACCTGG GACCCCCAGT GCATAAGCAT GGAAGGCAAA ATCCCCTATT 1500
TTCATGCTGG TGGATCCAAA TGTTCAACAT GGCCCTTACC ACAGCCCAGC CAGCACAACC 1560
CCAGATCCTC TTACCACAAT ATTACTGATG TGTGTGAGCT GGCTGTGGGC CCTGCAGGTG 1620
CACCGGCCAC TCTGTTGAAT GAAGCAGGTA AAGATGCTTT AAAATCCTCT CAAACCATTA 1680
AGTCTAGAGA AGAGGGAAAG GCAACCCAGC AGAGGGAGGT AGAAAGCTTC CATTCTGAGA 1740
CTGACCAGGA TACGCCCTGG CTGCTGCCCC AGGAGAAAAC CCCCTTTGGC TCCGCTAAAC 1800
CCTTGGATTA TGTGGAGATT CACAAGGTCA ACAAAGATGG TGCATTATCA TTGCTACCAA 1860
AACAGAGAGA GAACAGCGGC AAGCCCAAGA AGCCCGGGAC TCCTGAGAAC AATAAGGAGT 1920
ATGCCAAGGT GTCCGGGGTC ATGGATAACA ACATCCTGGT GTTGGTGCCA GATCCACATG 1980
CTAAAAACGT GGCTTGCTTT GAAGAATCAG CCAAAGAGGC CCCACCATCA CTTGAACAGA 2040
ATCAAGCTGA GAAAGCCCTG GCCAACTTCA CTGCAACATC AAGCAAGTGC AGGCTCCAGC 2100
TGGGTGGTTT GGATTACCTG GATCCCGCAT GTTTTACACA CTCCTTTCAC TGATAGCTTG 2160
ACTAATGGAA TGATTGGTTA AAATGTβATT TTTCTTCAGG TAACACTACA GAGTACGTGA 2220
AATGCTCAAG AATGTAGTCA GACTGACACT ACTAAAGCTC CCAGCTCCTT TCATGCTCCA 2280
TTTTTAACCA CTTGCCTCTT TCTCCAGCAG CTGATTCCAG AACAAATCAT TATGTTTCCT 2340
AACTGTGATT TGTAGATTTA CTTTTTGCTG TTAGTTATAA AACTATGTGT TCAATGAAAT 2400
AAAAGCACAC TGCTTAGTAT TCTTGAGGGA CAATGCCAAT AGGTATATCC TCTGGAAAAG 2460
GCTTTCATGA TTTGGCATGG GACAGACGGA AATGAAATTG TCAAAATTGT TTACCATAGA 2520
AAGATGACAA AAGAAAATTT TCCACATAGG AAAATGCCAT GAAAATTGCT TTTGAAAAAC 2580
AACTGCATAA CCTTTACACT CCTCGTCCAT TTTATTAGGA TTACCCAAAT ATAACCATTT 2640
AAAGAAAGAA TGCATTCCAG AACAAATTGT TTACATAAGT TCCTATACCT TACTGACACA 2700 TTGCTGATAT GCAAGTAAGA AAT
Seq ID NO: 112 Protein sequence Protein Accession ft: NP 000940
11 21 31 41 51
I I I I I
MKENVASATV FTLLLFLNTC LLNGQLPPGK PEIFKCRSPN KETFTCWWRP GTDGGLPTNY 60 SLTYHREGET LMHECPDYIT GGPNSCHFGK QYTSMWRTYI MMVNATNQMG SSFSDELYVD 120 VTYIVQPDPP LELAVEVKQP EDRKPYLWIK WSPPTLIDLK TGWFTLLYEI RLKPEKAAEW 180 EIHFAGQQTE FKILSLHPGQ KYLVQVRCKP DHGYWSAWSP ATFIQIPSDF TMNDTTVWIS 240 VAVLSAVICL IIVWAVALKG YSMVTCIFPP VPGPKIKGFD AHLLEKGKSE ELLSALGCQD 300 FPPTSDYEDL LVEYLEVDDS EDQHLMSVHS KEHPSQGMKP TYLDPDTDSG RGSCDSPSLL 360 SEKCEEPQAN PSTFYDPEVI EKPENPETTH TWDPQCISME GKIPYFHAGG SKCSTWPLPQ 420 PSQHNPRSSY HNITDVCELA VGPAGAPATL LNEAGKDALK SSQTIKSREE GKATQQREVE 480 SFHSETDQDT PWLLPQEKTP FGSAKPLDYV EIHKVNKDGA LSLLPKQREN SGKPKKPGTP 540 ENNKEYAKVS GVMDNNILVL VPDPHAKNVA CFEESAKEAP PSLEQNQAEK ALANFTATSS 600 KCRLQLGGLD YLDPACFTHS FH
Seq ID NO: 113 DNA sequence
Nucleic Acid Accession ft: XM_062811
Coding εequence: 1..888
11 21 31 41 51
I I I I I
ATGTGGGGCG CTCGCCGCTC GTCCGTCTCC TCATCCTGGA ACGCCGCTTC GCTCCTGCAG 60 CTGCTGCTGG CTGCGCTGCT GGCGGCGGGG GCGAGGGCCA GCGGCGAGTA CTGCCACGGC 120 TβGCTGGACG CGCAGGGCGT CTGGCGCATC GGCTTCCAGT GTCCCGAGCG CTTCGACGGC 180 GGCGACGCCA CCATCTGCTG CGGCAGCTGC GCGTTGCGCT ACTGCTGCTC CAGCGCCGAG 240 GCGCGCCTGG ACCAGGGCGG CTGCGACAAT GACCGCCAGC AGGGCGCTGG CGAGCCTGGC 300 CGGGCGGACA AAGACGGCCC GGACGGCTCG GCAGTGCCCA TCTACGTGCC GTTCCTCATT 360 GTTGGCTCCG TGTTTGTCGC CTTTATCATC TTGGGGTCCC TGGTGGCAGC CTGTTGCTGC 420 AGATGTCTCC GGCCTAAGCA GGATCCCCAG CAGAGCCGAG CCCCAGGGGG TAACCGCTTG 480 ATGGAGACCA TCCCCATGAT CCCCAGTGCC AGCACCTCCC GGGGGTCGTC CTCACGCCAG 540 TCCAGCACAG CTGCCAGTTC CAGCTCCAGC GCCAACTCAG GGGCCCGGGC GCCCCCAACA 600 AGGTCACAGA CCAACTGTTG CTTGCCGGAA GGGACCATGA ACAACGTGTA TGTCAACATG 660 CCCACGAATT TCTCTGTGCT GAACTGTCAG CAGGCCACCC AGATTGTGCC ACATCAAGGG 720 CAGTATCTGC ATCCCCCATA CGTGGGGTAC ACGGTGCAGC ACGACTCTGT GCCCATGACA 780 GCTGTGCCAC CTTTCATGGA CGGCCTGCAG CCTGGCTACA GGCAGATTCA GTCCCCCTTC 840 CCTCACACCA ACAGTGAACA GAAGATGTAC CCAGCGGTGA CTGTATAA
Seq ID NO: 114 Protein sequence Protein Accession tf: XP 062811
11 21 31 41 51
I I I I I
MWGARRSSVS SSWNAASLLQ LLLAALLAAG ARASGEYCHG WLDAQGVWRI GFQCPERFDG 60 GDATICCGSC ALRYCCSSAE ARLDQGGCDN DRQQGAGEPG RADKDGPDGS AVPIYVPFLI 120 VGSVFVAFII LGSLVAACCC RCLRPKQDPQ QSRAPGGNRL METIPMIPSA STSRGSSSRQ 180 SSTAASSSSS ANSGARAPPT RSQTNCCLPE GTMNNVYVNM PTNFSVLNCQ QATQIVPHQG 240 QYLHPPYVGY TVQHDSVPMT AVPPFMDGLQ PGYRQIQSPF PHTNSEQKMY PAVTV
Seq ID NO : 115 DNA sequence
Nucleic Acid Accession # : NM_013257
Coding sequence : 223 . .1512
11 21 31 41 51
GGTGTGCTCT TGAGGGATTA AATGCAAAGA GATCACACCA TGGACTACAA GGAAAGCTGC 60
CCAAGTGTAA GCATTCCCAG CTCCGATGAA CACAGAGAGA AAAAGAAGAG GTTTACTGTT 120
TATAAAGTTC TGGTTTCAGT GGGAAGAAGT GAATGGTTTG TCTTCAGGAG ATATGCAGAG 180
TTTGATAAAC TTTATAACAC TTTAAAAAAA CAGTTTCCTG CTATGGCCCT GAAGATTCCT 240
GCCAAGAGAA TATTTGGTGA TAATTTTGAT CCAGATTTTA TTAAACAAAG ACGAGCAGGA 300
CTAAACGAAT TCATTCAGAA CCTAGTTAGG TATCCAGAAC TTTATAACCA TCCAGATGTC 360
AGAGCATTCC TTCAAATGGA CAGTCCAAAA CACCAGTCAG ATCCATCTGA AGATGAGGAT 420
GAAAGAAGTT CTCAGAAGCT ACACTCTACC TCACAGAACA TCAACCTGGG ACCGTCTGGA 480
AATCCTCATG CCAAACCAAC TGACTTTGAT TTCTTAAAAG TTATTGGAAA AGGCAGCTTT 540
GGCAAGGTTC TTCTTGCAAA ACGGAAACTG GATGGAAAAT TTTATGCTGT CAAAGTGTTA 600
CAGAAAAAAA TAGTTCTCAA CAGAAAAGAG CAAAAACATA TTATGGCTGA ACGTAATGTG 660
CTCTTGAAAA ATGTGAAACA TCCGTTTTTG GTTGGATTGC ATTATTCCTT CCAAACAACT 720
GAAAAGCTTT ATTTTGTTCT GGATTTTGTT AATGGAGGGG AGCTTTTTTT CCACTTACAA 780
AGAGAACGGT CCTTTCCTGA GCACAGAGCT AGGTTTTACG CTGCTGAAAT TGCTAGTGCA 840
TTGGGTTACT TACATTCCAT CAAAATAGTA TACAGAGACT TGAAACCAGA AAATATTCTT 900
TTGGATTCAG TAGGACATGT TGTCTTAACA GATTTTGGGC TTTGTAAAGA AGGAATTGCT 960
ATTTCTGACA CCACTACCAC ATTTTGTGGG ACACCAGAGT ATCTTGCACC TGAAGTAATT 1020
AGAAAACAGC CCTATGACAA TACTGTAGAT TGGTGGTGCC TTGGGGCTGT TCTGTATGAA 1080
ATGCTGTATG GATTGCCTCC TTTTTATTGC CGAGATGTTG CTGAAATGTA TGACAATATC 1140
CTTCACAAAC CCCTAAGTTT GAGGCCAGGA GTGAGTCTTA CAGCCTGGTC CATTCTGGAA 1200
GAACTCCTAG AAAAAGACAG GCAAAATCGA CTTGGTGCCA AGGAAGACTT TCTTGAAATT 1260
CAGAATCATC CTTTTTTTGA ATCACTCAGC TGGGCTGACC TTGTACAAAA GAAGATTCCA 1320
CCACCATTTA ATCCTAATGT GGCTGGACCA GATGATATCA GAAACTTTGA CACAGCATTT 1380
ACAGAAGAAA CAGTTCCATA TTCTGTGTGT GTATCTTCTG ACTATTCTAT AGTGAATGCC 1440
AGTGTATTGG AGGCAGATGA TGCATTCGTT GGTTTCTCTT ATGCACCTCC TTCAGAAGAC 1500
TTATTTTTGT GAGCAGTTTG CCATTCAGAA ACCATTGAGC AAAATAAGTC TATAGATGGG 1560
ACTGAAACTT CTATTTGTGT GAATATATTC AAATATGTAT AACTAGTGCC TCATTTTTAT 1620
ATGTAATGAT GAAAACTATG AAAAAATGTA TTTTCTTCTA TGTGCAAGAA AAATAGGGCA 1680
TTTCAAAGAG CTGTTTTGAT TAAAATTTAT ATTCTTGTTT AATAAGCTTA TTTTTAAACA 1740
ATTTAAAAGC TATTATTCTT AGCATTAACC TATTTTTAAA GAAACCTTTT TTGCTATTGA 1800
CTGTTTTTTC CCTCTAAGTT TACACTAACA TCTACCCAAG ATAGACTGTT TTTTAACAGT 1860
CAATTTCAGT TCAGCTAACA TATATTAATA CCTTTGTAAC TCTTTGCTAT GGCTTTTGTT 1920
ATCACACCAA AACTATGCAA TTGGTACATG GTTGTTTAAG AAGAAACCGT ATTTTTCCAT 1980
GATAAATCAC TGTTTGAAAT ATTTGGTTCA TGGTATGATC GAAATGTAAA AGCATAATTA 2040
ACACATTGGC TGCTAGTTAA CAATTGGAAT AACTTTATTC TGCAGATCAT TTAAGAAGTA 2100
ACAGGCCGGG CGCGGTGGCT CACGCCTGTA ATCCCAGCAC TTTGGGAGGC TGAGGCGGGC 2160
AGATCACCTG AGGTCAGGAG TTGGAGACCA GCCTGACCAA CATGGACAAA CCCCGTCTCT 2220
ACTAAAAATA CAAAATTGGC AGGGTGTGGT GGCACATGCC TATAATCCCA GCTACTTGGG 2280
AGGCTAAGGC AGGAGAATCG CTTGAACCCG GGAGGCGGAG GTTGCAGTGA GCCGAGATCG 2340
CACCATTGCA CTCCTGCCTG GGCAACAAGA GTGAAACTCC ATCTCCAAAA A
Seq ID NO: 116 Protein εequence Protein Accession if: NP 037389
11 21 31 41 51
I I I I I I
MALKIPAKRI FGDNFDPDFI KQRRAGLNEF IQNLVRYPEL YNHPDVRAFL QMDSPKHQSD 60 PSEDEDERSS QKLHSTSQNI NLGPSGNPHA KPTDFDFLKV IGKGSFGKVL LAKRKLDGKF 120 YAVKVLQKKI VLNRKEQKHI MAERNVLLKN VKHPFLVGLH YSFQTTEKLY FVLDFVNGGE 180 LFFHLQRERS FPEHRARFYA AEIASALGYL HSIKIVYRDL KPENILLDSV GHWLTDFGL 240 CKEGIAISDT TTTFCGTPEY LAPEVIRKQP YDNTVDWWCL GAVLYEMLYG LPPFYCRDVA 300 EMYDNILHKP LSLRPGVSLT AWSILEELLE KDRQNRLGAK EDFLEIQNHP FFESLSWADL 360 VQKKIPPPFN PNVAGPDDIR NFDTAFTEET VPYSVCVSSD YSIVNASVLE ADDAFVGFSY 420 APPSEDLFL
Seq ID NO: 117 DNA sequence
Nucleic Acid Accession ft: NM 004004.1 Coding sequence: 1..681
11 21 31 41 51
ATGGATTGGG GCACGCTGCA GACGATCCTG GGGGGTGTGA ACAAACACTC CACCAGCATT 60 GGAAAGATCT GGCTCACCGT CCTCTTCATT TTTCGCATTA TGATCCTCGT TGTGGCTGCA 120 AAGGAGGTGT GGGGAGATGA GCAGGCCGAC TTTGTCTGCA ACACCCTGCA GCCAGGCTGC 180 AAGAACGTGT GCTACGATCA CTACTTCCCC ATCTCCCACA TCCGGCTATG GGCCCTGCAG 240 CTGATCTTCG TGTCCAGCCC AGCGCTCCTA GTGGCCATGC ACGTGGCCTA CCGGAGACAT 300 GAGAAGAAGA GGAAGTTCAT CAAGGGGGAG ATAAAGAGTG AATTTAAGGA CATCGAGGAG 360 ATCAAAACCC AGAAGGTCCG CATCGAAGGC TCCCTGTGGT GGACCTACAC AAGCAGCATC 420 TTCTTCCGGG TCATCTTCGA AGCCGCCTTC ATGTACGTCT TCTATGTCAT GTACGACGGC 480 TTCTCCATGC AGCGGCTGGT GAAGTGCAAC GCCTGGCCTT GTCCCAACAC TGTGGACTGC 540 TTTGTGTCCC GGCCCACGGA GAAGACTGTC TTCACAGTGT TCATGATTGC AGTGTCTGGA 600 ATTTGCATCC TGCTGAATGT CACTGAATTG TGTTATTTGC TAATTAGATA TTGTTCTGGG 660 AAGTCAAAAA AGCCAGTTTA A
Seq ID NO: 118 Protein sequence Protein Accession ft: NP_003995.1
1 11 21 31 41 51
I I I I I I
MDWGTLQTIL GGVNKHSTSI GKIWLTVLFI FRIMILWAA KEVWGDEQAD FVCNTLQPGC 60
KNVCYDHYFP ISHIRLWALQ LIFVSSPALL VAMHVAYRRH EKKRKFIKGE IKSEFKDIEE 120
IKTQKVRIEG SLWWTYTSSI FFRVIFEAAF MYVFYVMYDG FSMQRLVKCN AWPCPNTVDC 180
FVSRPTEKTV FTVFMIAVSG ICILLNVTEL CYLLIRYCSG KSKKPV
Seq ID NO: 119 DNA sequence Nucleic Acid Accession #: XM_061091.1 Coding sequence: 1..2481
11 21 31 41 51
I I I I I
ATGCCAAATA CTTCAGGAAC AACCAGGATT GAAATTTGGC TTCTCCAAGA GCCGCCCGGG 60
CACCGAGCGC TGGTCGCCGC TCTCCTTCCG GTGAGTCCCA GCCCCGAGTT GGCTCTGGCG 120
CCCGGGTACC CGCCAGTGCC GGCTGCCGAT GACCGATTCA CGCTCCCGAT GATTGGAGGT 180
CAGATGCATG GTGAGAAGGT AGATCTCTGG AGCCTTGGTG TTCTTTGCTA TGAATTTTTA 240
GTTGGGAAGC CTCCTTTTGA GGCAAACGAA GTCCATGTAA GCAAAGAAAC CATCGGGAAG 300
ATTTCAGCTG CCAGCAAAAT GATGTGGTGC TCGGCTGCAG TGGACATCAT GTTTCTGTTA 360
GATGGGTCTA ACAGCGTCGG GAAAGGGAGC TTTGAAAGGT CCAAGCACTT TGCCATCACA 420
GTCTGTGACG GTCTGGACAT CAGCCCCGAG AGGGTCAGAG TGGGAGCATT CCAGTTCAGT 480
TCCACTCCTC ATCTGGAATT CCCCTTGGAT TCATTTTCAA CCCAACAGGA AGTGAAGGCA 540
AGAATCAAGA GGATGGTTTT CAAAGGAGGG CGCACGGAGA CGGAACTTGC TCTGAAATAC 600
CTTCTGCACA GAGGGTTGCC TGGAGGCAGA AATGCTTCTG TGCCCCAGAT CCTCATCATC 660
GTCACTGATG GGAAGTCCCA GGGGGATGTG GCACTGCCAT CCAAGCAGCT GAAGGAAAGG 720
GGTGTCACTG TGTTTGCTGT GGGGGTCAGG TTTCCCAGGT GGGAGGAGCT GCATGCACTG 780
GCCAGCGAGC CTAGAGGGCA GCACGTGCTG TTGGCTGAGC AGGTGGAGGA TGCCACCAAC 840
GGCCTCTTCA GCACCCTCAG CAGCTCGGCC ATCTGCTCCA GCGCCACGCC AGCTGGGAGC 900
CCCGAGCTTG TCTTCATGGA GCGGTTAATG GGCATCTCTC TGATAGGCCC CTGTGACTCG 960
CAGCCCTGCG AGAATGGAGG CACATGTGTT CCAGAAGGAC TGGACGGCTA CCAGTGCCTC 1020
TGCCCGCTGG CCTTTGGAGG GGAGGCTAAC TGTGCCCTGA AGCTGAGCCT GGAATGCAGG 1080
GTCGACCTCC TCTTCCTGCT GGACAGCTCT GCGGGCACCA CTCTGGACGG CTTCCTGCGG 1140
GCCAAAGTCT TCGTGAAGCG GTTTGTGCGG GCCGTGCTGA GCGAGGACTC TCGGGCCCGA 1200
GTGGGTGTGG CCACATACAG CAGGGAGCTG CTGGTGGCGG TGCCTGTGGG GGAGTACCAG 1260
GATGTGCCTG ACCTGGTCTG GAGCCTCGAT GGCATTCCCT TCCGTGGTGG CCCCACCCTG 1320
ACGGGCAGTG CCTTGCGGCA GGCGGCAGAG CGTGGCTTCG GGAGCGCCAC CAβGACAGGC 1380
CAGGACCGGC CACGTAGAGT GGTGGTTTTG CTCACTGAGT CACACTCCGA GGATGAGGTT 1440
GCGGGCCCAG CGCGTCACGC AAGGGCGCGA GAGCTGCTCC TGCTGGGTGT AGGCAGTGAG 1500
GCCGTGCGGG CAGAGCTGGA GGAGATCACA GGCAGCCCAA AGCATGTGAT GGTCTACTCG 1560
GATCCTCAGG ATCTGTTCAA CCAAATCCCT GAGCTGCAGG GGAAGCTGTG CAGCCGGCAG 1620
CGGCCAGGGT GCCGGACACA AGCCCTGGAC CTCGTCTTCA TGTTGGACAC CTCTGCCTCA 1680
GTAGGGCCCG AGAATTTTGC TCAGATGCAG AGCTTTGTGA GAAGCTGTGC CCTCCAGTTT 1740
GAGGTGAACC CTGACGTGAC ACAGGTCGGC CTGGTGGTGT ATGGCAGCCA GGTGCAGACT 1800
GCCTTCGGGC TGGACACCAA ACCCACCCGG GCTGCGATGC TGCGGGCCAT TAGCCAGGCC 1860
CCCTACCTAG GTGGGGTGGG CTCAGCCGGC ACCGCCCTGC TGCACATCTA TGACAAAGTG 1920
ATGACCGTCC AGAGGGGTGC CCGGCCTGGT GTCCCCAAAG CTGTGGTGGT GCTCACAGGC 1980
GGGAGAGGCG CAGAGGATGC AGCCGTTCCT GCCCAGAAGC TGAGGAACAA TGGCATCTCT 2040
GTCTTGGTCG TGGGCGTGGG GCCTGTCCTA AGTGAGGGTC TGCGGAGGCT TGCAGGTCCC 2100
CGGGATTCCC TGATCCACGT GGCAGCTTAC GCCGACCTGC GGTACCACCA GGACGTGCTC 2160
ATTGAGTGGC TGTGTGGAGA AGCCAAGCAG CCAGTCAACC TCTGCAAACC CAGCCCGTGC 2220
ATGAATGAGG GCAGCTGCGT CCTGCAGAAT GGGAGCTACC GCTGCAAGTG TCGGGATGGC 2280
TGGGAGGGCC CCCACTGCGA GAACCGTGAG TGGAGCTCTT GCTCTGTATG TGTGAGCCAG 2340
GGATGGATTC TTGAGACGCC CCTGAGGCAC ATGGCTCCCG TGCAGGAGGG CAGCAGCCGT 2400
ACCCCTCCCA GCAACTACAG AGAAGGCCTG GGCACTGAAA TGGTGCCTAC CTTCTGGAAT 2460
GTCTGTGCCC CAGGTCCTTA G
Seq ID NO: 120 Protein εequence Protein Accession ft: XP_061091.1
1 11 21 31 41 51
I I I I I I
MPNTSGTTRI EIWLLQEPPG HRALVAALLP VSPSPELALA PGYPPVPAAD DRFTLPMIGG 60 QMHGEKVDLW SLGVLCYEFL VGKPPFEANE VHVSKETIGK ISAASKMMWC SAAVDIMFLL 120 DGSNSVGKGS FERSKHFAIT VCDGLDISPE RVRVGAFQFS STPHLEFPLD SFSTQQEVKA 180 RIKRMVFKGG RTETELALKY LLHRGLPGGR NASVPQILII VTDGKSQGDV ALPSKQLKER 240 GVTVFAVGVR FPRWEELHAL ASEPRGQHVL LAEQVEDATN GLFSTLSSSA ICSSATPAGS 300 PELVFMERLM GISLIGPCDS QPCQNGGTCV PEGLDGYQCL CPLAFGGEAN CALKLSLECR 360 VDLLFLLDSS AGTTLDGFLR AKVFVKRFVR AVLSEDSRAR VGVATYSREL LVAVPVGEYQ 420 DVPDLVWSLD GIPFRGGPTL TGSALRQAAE RGFGSATRTG QDRPRRVWL LTESHSEDEV 480 AGPARHARAR ELLLLGVGSE AVRAELEEIT GSPKHVMVYS DPQDLFNQIP ELQGKLCSRQ 540 RPGCRTQALD LVFMLDTSAS VGPENFAQMQ SFVRSCALQF EVNPDVTQVG LWYGSQVQT 600 AFGLDTKPTR AAMLRAISQA PYLGGVGSAG TALLHIYDKV MTVQRGARPG VPKAVWLTG 660 GRGAEDAAVP AQKLRNNGIS VLWGVGPVL SEGLRRLAGP RDSLIHVAAY ADLRYHQDVL 720 IEWLCGEAKQ PVNLCKPSPC MNEGSCVLQN GSYRCKCRDG WEGPHCENRE WSSCSVCVSQ 780 G ILETPLRH MAPVQEGSSR TPPSNYREGL GTEMVPTFWN VCAPGP
Seq ID NO: 121 DNA sequence Nucleic Acid Accession tt : Eos sequence Coding sequence: 1..2424
11 21 31 41 51
I I I I I
ATGCCCCCTT TCCTGTTGCT GGAGGCCβTC TGTGTTTTCC TGTTTTCCAG AGTGCCCCCA 60
TCTCTCCCTC TCCAGGAAGT CCATGTAAGC AAAGAAACCA TCGGGAAGAT TTCAGCTGCC 120
AGCAAAATGA TGTGGTGCTC GGCTGCAGTG GACATCATGT TTCTGTTAGA TGGGTCTAAC 180
AGCGTCGGGA AAGGGAGCTT TGAAAGGTCC AAGCACTTTG CCATCACAGT CTGTGACGGT 240
CTGGACATCA GCCCCGAGAG GGTCAGAGTG GGAGCATTCC AGTTCAGTTC CACTCCTCAT 300
CTGGAATTCC CCTTGGATTC ATTTTCAACC CAACAGGAAG TGAAGGCAAG AATCAAGAGG 360
ATGGTTTTCA AAGGAGGGCG CACGGAGACG GAACTTGCTC TGAAATACCT TCTGCACAGA 420
GGGTTGCCTG GAGGCAGAAA TGCTTCTGTG CCCCAGATCC TCATCATCGT CACTGATGGG 480
AAGTCCCAGG GGGATGTGGC ACTGCCATCC AAGCAGCTGA AGGAAAGGGG TGTCACTGTG 540
TTTGCTGTGG GGGTCAGGTT TCCCAGGTGG GAGGAGCTGC ATGCACTGGC CAGCGAGCCT 600
AGAGGGCAGC ACGTGCTGTT GGCTGAGCAG GTGGAGGATG CCACCAACGG CCTCTTCAGC 660
ACCCTCAGCA GCTCGGCCAT CTGCTCCAGC GCCACGCCAG ACTGCAGGGT CGAGGCTCAC 720
CCCTGTGAGC ACAGGACGCT GGAGATGGTC CGGGAGTTCG CTGGCAATGC CCCATGCTGG 780
AGAGGATCGC GGCGGACCCT TGCGGTGCTG GCTGCACACT GTCCCTTCTA CAGCTGGAAG 840
AGAGTGTTCC TAACCCACCC TGCCACCTGC TACAGGACCA CCTGCCCAGG CCCCTGTGAC 900
TCGCAGCCCT GCCAGAATGG AGGCACATGT GTTCCAGAAG GACTGGACGG CTACCAGTGC 960
CTCTGCCCGC TGGCCTTTGG AGGGGAGGCT AACTGTGCCC TGAAGCTGAG CCTGGAATGC 1020
AGGGTCGACC TCCTCTTCCT GCTGGACAGC TCTGCGGGCA CCACTCTGGA CGGCTTCCTG 1080
CGGGCCAAAG TCTTCGTGAA GCGGTTTGTG CGGGCCGTGC TGAGCGAGGA CTCTCGGGCC 1140
CGAGTGGGTG TGGCCACATA CAGCAGGGAG CTGCTGGTGG CGGTGCCTGT GGGGGAGTAC 1200
CAGGATGTGC CTGACCTGGT CTGGAGCCTC GATGGCATTC CCTTCCGTGG TGGCCCCACC 1260
CTGACGGGCA GTGCCTTGCG GCAGGCGGCA GAGCGTGGCT TCGGGAGCGC CACCAGGACA 1320
GGCCAGGACC GGCCACGTAG AGTGGTGGTT TTGCTCACTG AGTCACACTC CGAGGATGAG 1380
GTTGCGGGCC CAGCGCGTCA CGCAAGGGCG CGAGAGCTGC TCCTGCTGGG TGTAGGCAGT 1440
GAGGCCGTGC GGGCAGAGCT GGAGGAGATC ACAGGCAGCC CAAAGCATGT GATGGTCTAC 1500
TCGGATCCTC AGGATCTGTT CAACCAAATC CCTGAGCTGC AGGGGAAGCT GTGCAGCCGG 1560
CAGCGGCCAG GGTGCCGGAC ACAAGCCCTG GACCTCGTCT TCATGTTGGA CACCTCTGCC 1620
TCAGTAGGGC CCGAGAATTT TGCTCAGATG CAGAGCTTTG TGAGAAGCTG TGCCCTCCAG 1680
TTTGAGGTGA ACCCTGACGT GACACAGGTC GGCCTGGTGG TGTATGGCAG CCAGGTGCAG 1740
ACTGCCTTCG GGCTGGACAC CAAACCCACC CGGGCTGCGA TGCTGCGGGC CATTAGCCAG 1800
GCCCCCTACC TAGGTGGGGT GGGCTCAGCC GGCACCGCCC TGCTGCACAT CTATGACAAA 1860
GTGATGACCG TCCAGAGGGG TGCCCGGCCT GGTGTCCCCA AAGCTGTGGT GGTGCTCACA 1920
GGCGGGAGAG GCGCAGAGGA TGCAGCCGTT CCTGCCCAGA AGCTGAGGAA CAATGGCATC 1980
TCTGTCTTGG TCGTGGGCGT GGGGCCTGTC CTAAGTGAGG GTCTGCGGAG GCTTGCAGGT 2040
CCCCGGGATT CCCTGATCCA CGTGGCAGCT TACGCCGACC TGCGGTACCA CCAGGACGTG 2100
CTCATTGAGT GGCTGTGTGG AGAAGCCAAG CAGCCAGTCA ACCTCTGCAA ACCCAGCCCG 2160
TGCATGAATG AGGGCAGCTG CGTCCTGCAG AATGGGAGCT ACCGCTGCAA GTGTCGGGAT 2220
GGCTGGGAGG GCCCCCACTG CGAGAACCGT GAGTGGAGCT CTTGCTCTGT ATGTGTGAGC 2280
CAGGGATGGA TTCTTGAGAC GCCCCTGAGG CACATGGCTC CCGTGCAGGA GGGCAGCAGC 2340
CGTACCCCTC CCAGCAACTA CAGAGAAGGC CTGGGCACTG AAATGGTGCC TACCTTCTGG 2400
AATGTCTGTG CCCCAGGTCC TTAG
Seq ID NO: 122 Protein sequence Protein Accesεion ft: Eos sequence
11 21 31 41 51
MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN 60 SVGKGSFERS KHFAITVCDG LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR 120 MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180 FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240 PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300 SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL 360 RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT 420 LTGSALRQAA ERGFGSATRT GQDRPRRVW LLTESHSEDE VAGPARHARA RELLLLGVGS 480 EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540 SVGPENFAQM QΞFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600 APYLGGVGSA GTALLHIYDK VMTVQRGARP GVPKAWVLT GGRGAEDAAV PAQKLRNNGI 660 SVLWGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK QPVNLCKPSP 720 CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR EWSSCSVCVS QGWILETPLR HMAPVQEGSS 780 RTPPSNYREG LGTEMVPTFW NVCAPGP
Seq ID NO: 123 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 89..2356 11 21 31 41 51
I I I I
GCCCCCTGGC CCGAGCCGCG CCCGGGTCTG TGAGTAGAGC CGCCCGGGCA CCGAGCGCTG 60
GTCGCCGCTC TCCTTCCGTT ATATCAACAT GCCCCCTTTC CTGTTGCTGG AAGCCGTCTG 120
TGTTTTCCTG TTTTCCAGAG TGCCCCCATC TCTCCCTCTC CAGGAAGTCC ATGTAAGCAA 180
AGAAACCATC GGGAAGATTT CAGCTGCCAG CAAAATGATG TGGTGCTCGG CTGCAGTGGA 240
CATCATGTTT CTGTTAGATG GGTCTAACAG CGTCGGGAAA GGGAGCTTTG AAAGGTCCAA 300
GCACTTTGCC ATCACAGTCT GTGACGGTCT GGACATCAGC CCCGAGAGGG TCAGAGTGGG 360
AGCATTCCAG TTCAGTTCCA CTCCTCATCT GGAATTCCCC TTGGATTCAT TTTCAACCCA 420
ACAGGAAGTG AAGGCAAGAA TCAAGAGGAT GGTTTTCAAA GGAGGGCGCA CGGAGACGGA 480
ACTTGCTCTG AAATACCTTC TGCACAGAGG GTTGCCTGGA GGCAGAAATG CTTCTGTGCC 540
CCAGATCCTC ATCATCGTCA CTGATGGGAA GTCCCAGGGG GATGTGGCAC TGCCATCCAA 600
GCAGCTGAAG GAAAGGGGTG TCACTGTGTT TGCTGTGGGG GTCAGGTTTC CCAGGTGGGA 660
GGAGCTGCAT GCACTGGCCA GCGAGCCTAG AGGGCAGCAC GTGCTGTTGG CTGAGCAGGT 720
GGAGGATGCC ACCAACGGCC TCTTCAGCAC CCTCAGCAGC TCGGCCATCT GCTCCAGCGC 780
CACGCCAGAC TGCAGGGTCG AGGCTCACCC CTGTGAGCAC AGGACGCTGG AGATGGTCCG 840
GGAGTTCGCT GGCAATGCCC CATGCTGGAG AGGATCGCGG CGGACCCTTG CGGTGCTGGC 900
TGCACACTGT CCCTTCTACA GCTGGAAGAG AGTGTTCCTA ACCCACCCTG CCACCTGCTA 960
CAGGACCACC TGCCCAGGCC CCTGTGACTC GCAGCCCTGC CAGAATGGAG GCACATGTGT 1020
TCCAGAAGGA CTGGACGGCT ACCAGTGCCT CTGCCCGCTG GCCTTTGGAG GGGAGGCTAA 1080
CTGTGCCCTG AAGCTGAGCC TGGAATGCAG GGTCGACCTC CTCTTCCTGC TGGACAGCTC 1140
TGCGGGCACC ACTCTGGACG GCTTCCTGCG GGCCAAAGTC TTCGTGAAGC GGTTTGTGCG 1200
GGCCGTGCTG AGCGAGGACT CTCGGGCCCG AGTGGGTGTG GCCACATACA GCAGGGAGCT 1260
GCTGGTGGCG GTGCCTGTGG GGGAGTACCA GGATGTGCCT GACCTGGTCT GGAGCCTCGA 1320
TGGCATTCCC TTCCGTGGTG GCCCCACCCT GACGGGCAGT GCCTTGCGGC AGGCGGCAGA 1380
GCGTGGCTTC GGGAGCGCCA CCAGGACAGG CCAGGACCGG CCACGTAGAG TGGTGGTTTT 1440
GCTCACTGAG TCACACTCCG AGGATGAGGT TGCGGGCCCA GCGCGTCACG CAAGGGCGCG 1500
AGAGCTGCTC CTGCTGGGTG TAGGCAGTGA GGCCGTGCGG GCAGAGCTGG AGGAGATCAC 1560
AGGCAGCCCA AAGCATGTGA TGGTCTACTC GGATCCTCAG GATCTGTTCA ACCAAATCCC 1620
TGAGCTGCAG GGGAAGCTGT GCAGCCGGCA GCGGCCAGGG TGCCGGACAC AAGCCCTGGA 1680
CCTCGTCTTC ATGTTGGACA CCTCTGCCTC AGTAGGGCCC GAGAATTTTG CTCAGATGCA 1740
GAGCTTTGTG AGAAGCTGTG CCCTCCAGTT TGAGGTGAAC CCTGACGTGA CACAGGTCGG 1800
CCTGGTGGTG TATGGCAGCC AGGTGCAGAC TGCCTTCGGG CTGGACACCA AACCCACCCG 1860
GGCTGCGATG CTGCGGGCCA TTAGCCAGGC CCCCTACCTA GGTGGGGTGG GCTCAGCCGG 1920
CACCGCCCTG CTGCACATCT ATGACAAAGT GATGACCGTC CAGAGGGGTG CCCGGCCTGG 1980
TGTCCCCAAA GCTGTGGTGG TGCTCACAGG CGGGAGAGGC GCAGAGGATG CAGCCGTTCC 2040
TGCCCAGAAG CTGAGGAACA ATGGCATCTC TGTCTTGGTC GTGGGCGTGG GGCCTGTCCT 2100
AAGTGAGGGT CTGCGGAGGC TTGCAGGTCC CCGGGATTCC CTGATCCACG TGGCAGCTTA 2160
CGCCGACCTG CGGTACCACC AGGACGTGCT CATTGAGTGG CTGTGTGGAG AAGCCAAGCA 2220
GCCAGTCAAC CTCTGCAAAC CCAGCCCGTG CATGAATGAG GGCAGCTGCG TCCTGCAGAA 2280
TGGGAGCTAC CGCTGCAAGT GTCGGGATGG CTGGGAGGGC CCCCACTGCG AGAACCGATT 2340
CTTGAGACGC CCCTGAGGCA CATGGCTCCC GTGCAGGAGG GCAGCAGCCG TACCCCTCCC 2400
AGCAACTACA GAGAAGGCCT GGGCACTGAA ATGGTGCCTA CCTTCTGGAA TGTCTGTGCC 2460
CCAGGTCCTT AGAATGTCTG CTTCCCGCCG TGGCCAGGAC CACTATTCTC ACTGAGGGAG 2520
GAGGATGTCC CAACTGCAGC CATGCTGCTT AGAGACAAGA AAGCAGCTGA TGTCACCCAC 2580
AAACGATGTT GTTGAAAAGT TTTGATGTGT AAGTAAATAC CCACTTTCTG TACCTGCTGT 2640
GCCTTGTTGA GGCTATGTCA TCTGCCACCT TTCCCTTGAG GATAAACAAG GGGTCCTGAA 2700
GACTTAAATT TAGCGGCCTG ACGTTCCTTT GCACACAATC AATGCTCGCC AGAATGTTGT 2760
TGACACAGTA ATGCCCAGCA GAGGCCTTTA CTAGAGCATC CTTTGGACGG
Seq ID NO: 124 Protein sequence Protein Accession #: Eos sequence
11 21 31 41 51
MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN 60 SVGKGSFERS KHFAITVCDG LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR 120 MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180 FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240 PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300 SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL 360 RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT 420 LTGSALRQAA ERGFGSATRT GQDRPRRVW LLTESHSEDE VAGPARHARA RELLLLGVGS 480 EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540 SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600 APYLGGVGSA GTALLHIYDK VMTVQRGARP GVPKAVWLT GGRGAEDAAV PAQKLRNNGI 660 SVLWGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK QPVNLCKPSP 720 CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR FLRRP
Seq ID NO: 125 DNA sequence
Nucleic Acid Accesεion ft: NM_031942.1
Coding sequence: 145..1260
11 21 31 41 51
I I I I I
CCCGAGCCCC GCCCCTCCGG GCCCGGGTCG GCGCGCCCAG CCTGCCAGCC GCGCTGCTGC 60 TGCTCCTCCT GCTGTGGGAC CGCTGACCGC GCGGCTGCTC CGCTCTCCCC GCTCCAAGCG 120 CCGATCTGGG CACCCGCCAC CAGCATGGAC GCTCGCCGCG TGCCGCAGAA AGATCTCAGA 180 GTAAAGAAGA ACTTAAAGAA ATTCAGATAT GTGAAGTTGA TTTCCATGGA AACCTCGTCA 240 TCCTCTGATG ACAGTTGTGA CAGCTTTGCT TCTGATAATT TTGCAAACAC GAGGCTGCAG 300 TCAGTTCGGG AAGGCTGTAG GACCCGCAGC CAGTGCAGGC ACTCTGGACC TCTCAGGGTG 360 GCGATGAAGT TTCCAGCGCG GAGTACCAGG GGAGCAACCA ACAAAAAAGC AGAGTCCCGC 420 CAGCCCTCAG AGAATTCTGT GACTGATTCC AACTCCGATT CAGAAGATGA AAGTGGAATG 480 AATTTTTTGG AGAAAAGGGC TTTAAATATA AAGCAAAACA AAGCAATGCT TGCAAAACTC 540 ATGTCTGAAT TAGAAAGCTT CCCTGGCTCG TTCCGTGGAA GACATCCCCT CCCAGGCTCC 600 GACTCACAAT CAAGGAGACC GCGAAGGCGT ACATTCCCGG GTGTTGCTTC CAGGAGAAAC 660 CCTGAACGGA GAGCTCGTCC TCTTACCAGG TCAAGGTCCC GGATCCTCGG GTCCCTTGAC 720 GCTCTACCCA TGGAGGAGGA GGAGGAAGAG GATAAGTACA TGTTGGTGAG AAAGAGGAAG 780 ACCGTGGATG GCTACATGAA TGAAGATGAC CTGCCCAGAA GCCGTCGCTC CAGATCATCC 840 GTGACCCTTC CGCATATAAT TCGCCCAGTG GAAGAAATTA CAGAGGAGGA GTTGGAGAAC 900 GTCTGCAGCA ATTCTCGAGA GAAGATATAT AACCGTTCAC TGGGCTCTAC TTGTCATCAA 960 TGCCGTCAGA AGACTATTGA TACCAAAACA AACTGCAGAA ACCCAGACTG CTGGGGCGTT 1020 CGAGGCCAGT TCTGTGGCCC CTGCCTTCGA AACCGTTATG GTGAAGAGGT CAGGGATGCT 1080 CTGCTGGATC CGAACTGGCA TTGCCCGCCT TGTCGAGGAA TCTGCAACTG CAGTTTCTGC 1140 CGGCAGCGAG ATGGACGGTG TGCGACTGGG GTCCTTGTGT ATTTAGCCAA ATATCATGGC 1200 TTTGGGAATG TGCATGCCTA CTTGAAAAGC CTGAAACAGG AATTTGAAAT GCAAGCATAA 1260 TATCTGGAAA ATTTGCTGCC TGCCTTCTAC TTCTCAAATC TTTCTTGTAA AAGTTTCCAA 1320 TTTTTTCACT GAAACCTGAG TTAAAAATCT TGATGATCAG CCTGTTTCAT AAGAAACTCC 1380 AATCAAGTTA ATCTTAGCAG ACATGTGTTT CTGGAGCATC ACAGAAGGTA TATTGCTAGT 1440 TACACTTTGC CCTCCTGCAG TTTCTTCTCT GCTCCCAACC CCCATCTCAT AGCATCCCCC 1500 TCTATTTCCA ATGCTCCTCT CCAACCGCTT AGTTTCTGAA TTTCTTTTAA ATTACAGTTT 1560 TATGAAAGCA TATTTTATTT ACTTGGTGTT GAAATAGCCC TCATAAAACC TAAGCACTTG 1620 GAAACACAAT AATAGTATTA ACTAACTAGA TCTATTGAAT TTCAGAGAAG AGCCTTCTAA 1680 CTTGTTTACA CAAAAACGAG TATGATTTAG CACTCATACT AGTTGAAATT TTTAATAGAA 1740 TCAAGGCACA AAAGTCTTAA AACCATGTGG AAAAATTAGG TAATTATTGC AGATTGATGT 1800 CTCTCAATCC CATGTATTGC GCTTATGTTA CAAGTTGTTG TCACAGTTGA GACTTAATTT 1860 CTCCTAATTT CTTCTGCCCG AAGGGTAAGT GGTGCGTCCA GCTTACACGA TCATAATTCA 1920 AAGGTTGGTG GGCAATGTAA TACTTAATTA AAATAATGAT GGAAGAGCTA TCTGGAGATT 1980 ATGAGTAAGC TGATTTGAAT TTTCAGTATA AAACTTTAGT ATAATTGTAG TTTGCAAAGT 2040 TTATTTCAGT TCACATGTAA GGTATTGCAA ATAAATTCTT GGACAATTTT GTATGGAAAC 2100 TTGATATTAA AAACTAGTCT GTGGTTCTTT GCAGTTTCTT GTAAATTTAT AAACCAGGCA 2160 CAAGGTTCAA GTTTAGATTT TAAGCACTTT TATAACAATG ATAAGTGCCT TTTTGGAGAT 2220 GTAACTTTTA GCAGTTTGTT AACCTGACAT CTCTGCCAGT CTAGTTTCTG GGCAGGTTTC 2280 CTGTGTCAGT ATTCCCCCTC CTCTTTGCAT TAATCAAGGT ATTTGGTAGA GGTGGAATCT 2340 AAGTGTTTGT ATGTCCAATT TACTTGCATA TGTAAACCAT TGCTGTGCCA TTCAATGTTT 2400 GATGCATAAT TGGACCTTGA ATCGATAAGT GTAAATACAG CTTTTGATCT GTAATGCTTT 2460 TATACAAAAG TTTATTTTAA TAATAAAATG TTTGTTCTAA AAAAAAAAAA
Seq ID NO: 126 Protein sequence Protein Accession it: NP 114148.1
11 21 31 41 51
I I I I I
MDARRVPQKD LRVKKNLKKF RYVKLISMET SSSSDDSCDS FASDNFANTR LQSVREGCRT 60 RSQCRHSGPL RVAMKFPARS TRGATNKKAE SRQPSENSVT DSNSDSEDES GMNFLEKRAL 120 NIKQNKAMLA KLMSELESFP GSFRGRHPLP GSDSQSRRPR RRTFPGVASR RNPERRARPL 180 TRSRSRILGS LDALPMEEEE EEDKYMLVRK RKTVDGYMNE DDLPRSRRSR SSVTLPHIIR 240 PVEEITEEEL ENVCSNSREK IYNRSLGSTC HQCRQKTIDT KTNCRNPDCW GVRGQFCGPC 300 LRNRYGEEVR DALLDPNWHC PPCRGICNCS FCRQRDGRCA TGVLVYLAKY HGFGNVHAYL 360 KSLKQEFEMQ A
Seq ID NO: 127 DNA sequence
Nucleic Acid Accession ft: AF305616.1
Coding sequence: 1..863
11 21 31 41 51
I I I I I
ATGCACCGCT TGATGGGGGT CAACAGCACC GCCGCCGCCG CCGCCGGGCA GCCCAATGTC 60 TCCTGCACGT GCAACTGCAA ACGCTCTTTG TTCCAGAGCA TGGAGATCAC GGAGCTGGAG 120 TTTGTTCAGA TCATCATCAT CGTGGTGGTG ATGATGGTGA TGGTGGTGGT GATCACGTGC 180 CTGCTGAGCC ACTACAAGCT GTCTGCACGG TCCTTCATCA GCCGGCACAG CCAGGGGCGG 240 AGGAGAGAAG ATGCCCTGTC CTCAGAAGGA TGCCTGTGGC CCTCGGAGAG CACAGTGTCA 300 GGCAACGGAA TCCCAGAGCC GCAGGTCTAC GCCCCGCCTC GGCCCACCGA CCGCCTGGCC 360 GTGCCGCCCT TCGCCCAGCG GGAGCGCTTC CACCGCTTCC AGCCCACCTA TCCGTACCTG 420 CAGCACGAGA TCGACCTGCC ACCCACCATC TCGCTGTCAG ACGGGGAGGA GCCCCCACCC 480 TACCAGGGCC CCTGCACCCT CCAGCTTCGG GACCCCGAGC AGCAGCTGGA ACTGAACCGG 540 GAGTCGGTGC GCGCACCCCC AAACAGAACC ATCTTCGACA GTGACCTGAT GGATAGTGCC 600 AGGCTGGGCG GCCCCTGCCC CCCCAGCAGT AACTCGGGCA TCAGCGCCAC GTGCTACGGC 660 AGCGGCGGGC GCATGGAGGG GCCGCCGCCC ACCTACAGCG AGGTCATCGG CCACTACCCG 720 GGGTCCTCCT TCCAGCACCA GCAGAGCAGT GGGCCGCCCT CCTTGCTGGA GGGGACCCGG 780 CTCCACCACA CACACATCGC GCCCCTAGAG AGCGCAGCCA TCTGGAGCAA AGAGAAGGAT 840 AAACAGAAAG GACACCCTCT CTAG
Seq ID NO: 128 Protein sequence Protein Accession ft: AAL09357.1
1 11 21 31 41 51
I I I I I I
MHRLMGVNST AAAAAGQPNV SCTCNCKRSL FQSMEITELE FVQIIIIVW MMVMVWITC 60
LLSHYKLSAR SFISRHSQGR RREDALSSEG CLWPSESTVS GNGIPEPQVY APPRPTDRLA 120
VPPFAQRERF HRFQPTYPYL QHEIDLPPTI SLSDGEEPPP YQGPCTLQLR DPEQQLELNR 180
ESVRAPPNRT IFDSDLMDSA RLGGPCPPSS NSGISATCYG SGGRMEGPPP TYSEVIGHYP 240 GSSFQHQQSS GPPSLLEGTR LHHTHIAPLE SAAIWSKEKD KQKGHPL
Seq ID NO: 129 DNA sequence
Nucleic Acid Accession ft: NM 004952.1 Coding sequence : 1..718
11 21 31 41 51
I I I I I
ATGGCGGCGG CTCCGCTGCT GCTGCTGCTG CTGCTCGTGC CCGTGCCGCT GCTGCCGCTG 60 CTGGCCCAAG GGCCCGGAGG GGCGCTGGGA AACCGGCATG CGGTGTACTG GAACAGCTCC 120 AACCAGCACC TGCGGCGAGA GGGCTACACC GTGCAGGTGA ACGTGAACGA CTATCTGGAT 180 ATTTACTGCC CGCACTACAA CAGCTCGGGG GTGGGCCCCG GGGCGGGACC GGGGCCCGGA 240 GGCGGGGCAG AGCAGTACGT GCTGTACATG GTGAGCCGCA ACGGCTACCG CACCTGCAAC 300 GCCAGCCAGG GCTTCAAGCG CTGGGAGTGC AACCGGCCGC AcσccccσcA CAGCCCCATC 360 AAGTTCTCGG AGAAGTTCCA GCGCTACAGC GCCTTCTCTC TGGGCTACGA GTTCCACGCC 420 GGCCACGAGT ACTACTACAT CTCCACGCCC ACTCACAACC TGCACTGGAA GTGTCTGAGG 480 ATGAAGGTGT TCGTCTGCTG CGCCTCCACA TCGCACTCCG GGGAGAAGCC GGTCCCCACT 540 CTCCCCCAGT TCACCATGGG CCCCAATGTG AAGATCAACG TGCTGGAAGA CTTTGAGGGA 600 GAGAACCCTC AGGTGCCCAA GCTTGAGAAG AGCATCAGCG GGACCAGCCC CAAACGGGAA 660 CACCTGCCCC TGGCCGTGGG CATCGCCTTC TTCCTCATGA CGTTCTTGGC CTCCTAG
Seq ID NO: 130 Protein sequence Protein Accession ft: NP_004943.1
1 11 21 31 41 51
I I I I I I
MAAAPLLLLL LLVPVPLLPL LAQGPGGALG NRHAVYWNSS NQHLRREGYT VQVNVNDYLD 60 IYCPHYNSSG VGPGAGPGPG GGAEQYVLYM VSRNGYRTCN ASQGFKRWEC NRPHAPHSPI 120 KFSEKFQRYS AFSLGYEFHA GHEYYYISTP THNLHWKCLR MKVFVCCAST SHSGEKPVPT 180 LPQFTMGPNV KINVLEDFEG ENPQVPKLEK SISGTSPKRE HLPLAVGIAF FLMTFLAS
Seq ID NO: 131 DNA sequence
Nucleic Acid Accession ft: NM_012445.1
Coding sequence: 276..1271
11 21 41 51
I I I I
GCACGAGGGA AGAGGGTGAT CCGACCCGGG GAAGGTCGCT GGGCAGGGCG AGTTGGGAAA 60 GCGGCAGCCC CCGCCGCCCC CGCAGCCCCT TCTCCTCCTT TCTCCCACGT CCTATCTGCC 120 TCTCGCTGGA GGCCAGGCCG TGCAGCATCG AAGACAGGAG GAACTGGAGC CTCATTGGCC 180 GGCCCGGGGC GCCGGCCTCG GGCTTAAATA GGAGCTCCGG GCTCTGGCTG GGACCCGACC 240 GCTGCCGGCC GCGCTCCCGC TGCTCCTGCC GGGTGATGGA AAACCCCAGC CCGGCCGCCG 300 CCCTGGGCAA GGCCCTCTGC GCTCTCCTCC TGGCCACTCT CGGCGCCGCC GGCCAGCCTC 360 TTGGGGGAGA GTCCATCTGT TCCGCCAGAG CCCCGGCCAA ATACAGCATC ACCTTCACGG 420 GCAAGTGGAG CCAGACGGCC TTCCCCAAGC AGTACCCCCT GTTCCGCCCC CCTGCGCAGT 480 GGTCTTCGCT GCTGGGGGCC GCGCATAGCT CCGACTACAG CATGTGGAGG AAGAACCAGT 540 ACGTCAGTAA CGGGCTGCGC GACTTTGCGG AGCGCGGCGA GGCCTGGGCG CTGATGAAGG 600 AGATCGAGGC GGCGGGGGAG GCGCTGCAGA GCGTGCACGC GGTGTTTTCG GCGCCCGCCG 660 TCCCCAGCGG CACCGGGCAG ACGTCGGCGG AGCTGGAGGT GCAGCGCAGG CACTCGCTGG 720 TCTCGTTTGT GGTGCGCATC GTGCCCAGCC CCGACTGGTT CGTGGGCGTG GACAGCCTGG 780 ACCTGTGCGA CGGGGACCGT TGGCGGGAAC AGGCGGCGCT GGACCTGTAC CCCTACGACG 840 CCGGGACGGA CAGCGGCTTC ACCTTCTCCT CCCCCAACTT CGCCACCATC CCGCAGGACA 900 CGGTGACCGA GATAACGTCC TCCTCTCCCA GCCACCCGGC CAACTCCTTC TACTACCCGC 960 GGCTGAAGGC CCTGCCTCCC ATCGCCAGGG TGACACTGGT GCGGCTGCGA CAGAGCCCCA 1020 GGGCCTTCAT CCCTCCCGCC CCAGTCCTGC CCAGCAGGGA CAATGAGATT GTAGACAGCG 1080 CCTCAGTTCC AGAAACGCCG CTGGACTGCG AGGTCTCCCT GTGGTCGTCC TGGGGACTGT 1140 GCGGAGGCCA CTGTGGGAGG CTCGGGACCA AGAGCAGGAC TCGCTACGTC CGGGTCCAGC 1200 CCGCCAACAA CGGGAGCCCC TGCCCCGAGC TCGAAGAAGA GGCTGAGTGC GTCCCTGATA 1260 ACTGCGTCTA AGACCAGAGC CCCGCAGCCC CTGGGGCCCC CGGAGCCATG GGGTGTCGGG 1320 GGCTCCTGTG CAGGCTCATG CTGCAGGCGG CCGAGGCACA GGGGGTTTCG CGCTGCTCCT 1380 GACCGCGGTG AGGCCGCGCC GACCATCTCT GCACTGAAGG GCCCTCTGGT GGCCGGCACG 1440 GGCATTGGGA AACAGCCTCC TCCTTTCCCA ACCTTGCTTC TTAGGGGCCC CCGTGTCCCG 1500 TCTGCTCTCA GCCTCCTCCT CCTGCAGGAT AAAGTCATCC CCAAGGCTCC AGCTACTCTA 1560 AATTATGGTC TCCTTATAAG TTATTGCTGC TCCAGGAGAT TGTCCTTCAT CGTCCAGGGG 1620 CCTGGCTCCC ACGTGGTTGC AGATACCTCA GACCTGGTGC TCTAGGCTGT GCTGAGCCCA 1680 CTCTCCCGAG GGCGCATCCA AGCGGGGGCC ACTTGAGAAG TGAATAAATG GGGCGGTTTC 1740 GGAAGCGTCA GTGTTTCCAT GTTATGGATC TCTCTGCGTT TGAATAAAGA CTATCTCTGT 1800 TGCTCAC
Seq ID NO: 132 Protein sequence Protein Accession #: NP 036577.1
60
120
180
Figure imgf001003_0001
240
LVRLRQSPRA FIPPAPVLPS RDNEIVDSAS VPETPLDCEV SLWSSWGLCG GHCGRLGTKS 300
RTRYVRVQPA NNGSPCPELE EEAECVPDNC V
Seq ID NO: 133 DNA sequence
Nucleic Acid Accession ft: NM_019894 Coding sequence: 1..1314
1 11 21 31 41 51
I I I I I I
ATGTTACAGG ATCCTGACAG TGATCAACCT CTGAACAGCC TCGATGTCAA ACCCCTGCGC 60 AAACCCCGTA TCCCCATGGA GACCTTCAGA AAGGTGGGGA TCCCCATCAT CATAGCACTA 120 CTGAGCCTGG CGAGTATCAT CATTGTGGTT GTCCTCATCA AGGTGATTCT GGATAAATAC 180 TACTTCCTCT GCGGGCAGCC TCTCCACTTC ATCCCGAGGA AGCAGCTGTG TGACGGAGAG 240 CTGGACTGTC CCTTGGGGGA GGACGAGGAG CACTGTGTCA AGAGCTTCCC CGAAGGGCCT 300 GCAGTGGCAG TCCGCCTCTC CAAGGACCGA TCCACACTGC AGGTGCTGGA CTCGGCCACA 360 GGGAACTGGT TCTCTGCCTG TTTCGACAAC TTCACAGAAG CTCTCGCTGA GACAGCCTGT 420 AGGCAGATGG GCTACAGCAG CAAACCCACT TTCAGAGCTG TGGAGATTGG CCCAGACCAG 480 GATCTGGATG TTGTTGAAAT CACAGAAAAC AGCCAGGAGC TTCGCATGCG GAACTCAAGT 540 GGGCCCTGTC TCTCAGGCTC CCTGGTCTCC CTGCACTGTC TTGCCTGTGG GAAGAGCCTG 600 AAGACCCCCC GTGTGGTGGG TGGGGAGGAG GCCTCTGTGG ATTCTTGGCC TTGGCAGGTC 660 AGCATCCAGT ACGACAAACA GCACGTCTGT GGAGGGAGCA TCCTGGACCC CCACTGGGTC 720 CTCACGGCAG CCCACTGCTT CAGGAAACAT ACCGATGTGT TCAACTGGAA GGTGCGGGCA 780 GGCTCAGACA AACTGGGCAG CTTCCCATCC CTGGCTGTGG CCAAGATCAT CATCATTGAA 840 TTCAACCCCA TGTACCCCAA AGACAATGAC ATCGCCCTCA TGAAGCTGCA GTTCCCACTC 900 ACTTTCTCAG GCACAGTCAG GCCCATCTGT CTGCCCTTCT TTGATGAGGA GCTCACTCCA 960 GCCACCCCAC TCTGGATCAT TGGATGGGGC TTTACGAAGC AGAATGGAGG GAAGATGTCT 1020 GACATACTGC TGCAGGCGTC AGTCCAGGTC ATTGACAGCA CACGGTGCAA TGCAGACGAT 1080 GCGTACCAGG GGGAAGTCAC CGAGAAGATG ATGTGTGCAG GCATCCCGGA AGGGGGTGTG 1140 GACACCTGCC AGGGTGACAG TGGTGGGCCC CTGATGTACC AATCTGACCA GTGGCATGTG 1200 GTGGGCATCG TTAGCTGGGG CTATGGCTGC GGGGGCCCGA GCACCCCAGG AGTATACACC 1260 AAGGTCTCAG CCTATCTCAA CTGGATCTAC AATGTCTGGA AGGCTGAGCT GTAA
Seq ID NO: 134 Protein sequence Protein Accession ft: NP 063947.1
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIW VLIKVILDKY 60
YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT 120
GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDWEITEN SQELRMRNSS 180
GPCLSGSLVS LHCLACGKSL KTPRWGGEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV 240
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL 300
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD 360
AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT 420
Seq ID NO: 135 DNA sequence
Nucleic Acid Accession #: NM_003045 Coding sequence: 148..2037
11 21 31 41 51
I I I I I
CGATCCTGCC GGAGCCCCGC CGCCGCCGGC TTGGATTCTG AAACCTTCCT TGTATCCCTC 60 CTGAGACATC TTTGCTGCAA GATCGAGGCT GTCCTCTGGT GAGAAGGTGG TGAGGCTTCC 120 CGTCATATTC CAGCTCTGAA CAGCAACATG GGGTGCAAAG TCCTGCTCAA CATTGGGCAG 180 CAGATGCTGC GGCGGAAGGT GGTGGACTGT AGCCGGGAGG AGACGCGGCT GTCTCGCTGC 240 CTGAACACTT TTGATCTGGT GGCCCTCGGG GTGGGCAGCA CACTGGGTGC TGGTGTCTAC 300 GTCCTGGCTG GAGCTGTGGC CCGTGAGAAT GCAGGCCCTG CCATTGTCAT CTCCTTCCTG 360 ATCGCTGCGC TGGCCTCAGT GCTGGCTGGC CTGTGCTATG GCGAGTTTGG TGCTCGGGTC 420 CCCAAGACGG GCTCAGCTTA CCTCTACAGC TATGTCACCG TTGGAGAGCT CTGGGCCTTC 480 ATCACCGGCT GGAACTTAAT CCTCTCCTAC ATCATCGGTA CTTCAAGCGT AGCGAGGGCC 540 TGGAGCGCCA CCTTCGACGA GCTGATAGGC AGACCCATCG GGGAGTTCTC ACGGACACAC 600 ATGACTCTGA ACGCCCCCGG CGTGCTGGCT GAAAACCCCG ACATATTCGC AGTGATCATA 660 ATTCTCATCT TGACAGGACT TTTAACTCTT GGTGTGAAAG AGTCGGCCAT GGTCAACAAA 720 ATATTCACTT GTATTAACGT CCTGGTCCTG GGCTTCATAA TGGTGTCAGG ATTTGTGAAA 780 GGATCGGTTA AAAACTGGCA GCTCACGGAG GAGGATTTTG GGAACACATC AGGCCGTCTC 840 TGTTTGAACA ATGACACAAA AGAAGGGAAG CCCGGTGTTG GTGGATTCAT GCCCTTCGGG 900 TTCTCTGGTG TCCTGTCGGG GGCAGCGACT TGCTTCTATG CCTTCGTGGG CTTTGACTGC 960 ATCGCCACCA CAGGTGAAGA GGTGAAGAAC CCACAGAAGG CCATCCCCGT GGGGATCGTG 1020 GCGTCCCTCT TGATCTGCTT CATCGCCTAC TTTGGGGTGT CGGCTGCCCT CACGCTCATG 1080 ATGCCCTACT TCTGCCTGGA CAATAACAGC CCCCTGCCCG ACGCCTTTAA GCACGTGGGC 1140 TGGGAAGGTG CCAAGTACGC AGTGGCCGTG GGCTCCCTCT GCGCTCTTTC CGCCAGTCTT 1200 CTAGGTTCCA TGTTTCCCAT GCCTCGGGTT ATCTATGCCA TGGCTGAGGA TGGACTGCTA 1260 TTTAAATTCT TAGCCAACGT CAATGATAGG ACCAAAACAC CAATAATCGC CACATTAGCC 1320 TCGGGTGCCG TTGCTGCTGT GATGGCCTTC CTCTTTGACC TGAAGGACTT GGTGGACCTC 1380 ATGTCCATTG GCACTCTCCT GGCTTACTCG TTGGTGGCTG CCTGTGTGTT GGTCTTACGG 1440 TACCAGCCAG AGCAGCCTAA CCTGGTATAC CAGATGGCCA GTACTTCCGA CGAGTTAGAT 1500 CCAGCAGACC AAAATGAATT GGCAAGCACC AATGATTCCC AGCTGGGGTT TTTACCAGAG 1560 GCAGAGATGT TCTCTTTGAA AACCATACTC TCACCCAAAA ACATGGAGCC TTCCAAAATC 1620 TCTGGGCTAA TTGTGAACAT TTCAACCAGC CTTATAGCTG TTCTCATCAT CACCTTCTGC 1680 ATTGTGACCG TGCTTGGAAG GGAGGCTCTC ACCAAAGGGG CGCTGTGGGC AGTCTTTCTG 1740 CTCGCAGGGT CTGCCCTCCT CTGTGCCGTG GTCACGGGCG TCATCTGGAG GCAGCCCGAG 1800 AGCAAGACCA AGCTCTCATT TAAGGTTCCC TTCCTGCCAG TGCTCCCCAT CCTGAGCATC 1860 TTCGTGAACG TCTATCTCAT GATGCAGCTG GACCAGGGCA CCTGGGTCCG GTTTGCTGTG 1920 TGGATGCTGA TAGGCTTCAT CATCTACTTT GGCTATGGCC TGTGGCACAG CGAGGAGGCG 1980 TCCCTGGATG CCGACCAAGC AAGGACTCCT GACGGCAACT TGGACCAGTG CAAGTGACGC 2040 ACAGCCCCGC CCCCCGGAGG TGGCAGCAGC CCCGAGGGAC GCCCCCAGAG GACCGGGAGG 2100 CACCCCACCC TCCCCACCAG TGCAACAGAA ACCACCTGCG TCCACACCCT CACTGCA
Seq ID NO: 136 Protein sequence Protein Accesεion #: NM 003045
21 MGCKVLLNIG QQMLRRKWD CSREETRLSR CLNTFDLVAL GVGSTLGAGV YVLAGAVARE 60
NAGPAIVISF LIAALASVLA GLCYGEFGAR VPKTGSAYLY SYVTVGELWA FITGWNLILS 120
YIIGTSSVAR AWSATFDELI GRPIGEFSRT HMTLNAPGVL AENPDIFAVI IILILTGLLT 180
LGVKESAMVN KIFTCINVLV LGFIMVSGFV KGSVKNWQLT EEDFGNTSGR LCLNNDTKEG 240
KPGVGGFMPF GFSGVLSGAA TCFYAFVGFD CIATTGEEVK NPQKAIPVGI VASLLICFIA 300
YFGVSAALTL MMPYFCLDNN SPLPDAFKHV GWEGAKYAVA VGSLCALSAS LLGSMFPMPR 360
VIYAMAEDGL LFKFLANVND RTKTPIIATI ASGAVAAVMA FLFDLKDLVD LMSIGTLLAY 420
SLVAACVDVL RYQPEQPNLV YQMASTSDEL DPADQNELAS TNDSQLGFLP EAEMFSLKTI 480
LSPKNMEPSK ISGLIVNIST SLIAVLIITF CIVTVLGREA LTKGALWAVF LLAGSALLCA 540
WTGVIWRQP ESKTKLSFKV PFLPVLPILS IFVNVYLMMQ LDQGTWVRFA VWMLIGFIIY 600
FGYGLWHSEE ASLDADQART PDGNLDQCK
Seq ID NO: 137 DNA sequence
Nucleic Acid Accession it: NM_032044.1 Coding sequence: 182..658
11 21 31 41 51
AAGATATAAA AGCTCCAGAA ACGTTGACTG GGACCACTGG AGACACTGAA GAAGGCAGGG 60 GCCCTTAGAG TCTTGGTTGC CAAACAGATT TGCAGATCAA GGAGAACCCA GGAGTTTCAA 120 AGAAGCGCTA GTAAGGTCTC TGAGATCCTT GCACTAGCTA CATCCTCAGG GTAGGAGGAA 180 GATGGCTTCC AGAAGCATGC GGCTGCTCCT ATTGCTGAGC TGCCTGGCCA AAACAGGAGT 240 CCTGGGTGAT ATCATCATGA GACCCAGCTG TGCTCCTGGA TGGTTTTACC ACAAGTCCAA 300 TTGCTATGGT TACTTCAGGA AGCTGAGGAA CTGGTCTGAT GCCGAGCTCG AGTGTCAGTC 360 TTACGGAAAC GGAGCCCACC TGGCATCTAT CCTGAGTTTA AAGGAAGCCA GCACCATAGC 420 AGAGTACATA AGTGGCTATC AGAGAAGCCA GCCGATATGG ATTGGCCTGC ACGACCCACA 480 GAAGAGGCAG CAGTGGCAGT GGATTGATGG GGCCATGTAT CTGTACAGAT CCTGGTCTGG 540 CAAGTCCATG GGTGGGAACA AGCACTGTGC TGAGATGAGC TCCAATAACA ACTTTTTAAC 600 TTGGAGCAGC AACGAATGCA ACAAGCGCCA ACACTTCCTG TGCAAGTACC GACCATAGAG 660 CAAGAATCAA GATTCTGCTA ACTCCTGCAC AGCCCCGTCC TCTTCCTTTC TGCTAGCCTG 720 GCTAAATCTG CTCATTATTT CAGAGGGGAA ACCTAGCAAA CTAAGAGTGA TAAGGGCCCT 780 ACTACACTGG CTTTTTTAGG CTTAGAGACA GAAACTTTAG CATTGGCCCA GTAGTGGCTT 840 CTAGCTCTAA ATGTTTGCCC CGCCATCCCT TTCCACAGTA TCCTTCTTCC CTCCTCCCCT 900 GTCTCTGGCT GTCTCGAGCA GTCTAGAAGA GTGCATCTCC AGCCTATGAA ACAGCTGGGT 960 CTTTGGCCAT AAGAAGTAAA GATTTGAAGA CAGAAGGAAG AAACTCAGGA GTAAGCTTCT 1020 AGACCCCTTC AGCTTCTACA CCCTTCTGCC CTCTCTCCAT TGCCTGCACC CCAGCCCAGC 1080 CACTCAACTC CTGCTTGTTT TTCCTTTGGC CATAGGAAGG TTTACCAGTA GAATCCTTGC 1140 TAGGTTGATG TGGGCCATAC ATTCCTTTAA TAAACCATTG TGTACATAAG AAAAAAAAAA
Seq ID NO: 138 Protein sequence Protein Accession ft: NP 114433.1
1 11 21 31 41 51
I I I I I I
MASRSMRLLL LLSCLAKTGV LGDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS 60 YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG 120 KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
Seq ID NO: 139 DNA sequence
Nucleic Acid Accession #: XM_051860.2
Coding sequence: 52..3042
60
120
Figure imgf001005_0001
180
CCCAAACTCA CAGTCACCAT TGACACCAAT GTGAACAGCA CCATTCTGAA CTTGGAGGAT 240
AATGTACAGT CATGGAAACC TGGAGATACC CTGGTCATTG CCAGTACTGA TTACTCCATG 300
TACCAGGCAG AAGAGTTCCA GGTGCTTCCC TGCAGATCCT GCGCCCCCAA CCAGGTCAAA 360
GTGGCAGGGA AACCAATGTA CCTGCACATC GGGGAGGAGA TAGACGGCGT GGACATGCGG 420
GCGGAGGTTG GGCTTCTGAG CCGGAACATC ATAGTGATGG GGGAGATGGA GGACAAATGC 480
TACCCCTACA GAAACCACAT CTGCAATTTC TTTGACTTCG ATACCTTTGG GGGCCACATC 540
AAGTTTGCTC TGGGATTTAA GGCAGCACAC TTGGAGGGCA CGGAGCTGAA GCATATGGGA 600
CAGCAGCTGG TGGGTCAGTA CCCGATTCAC TTCCACCTGG CCGGTGATGT AGACGAAAGG 660
GGAGGTTATG ACCCACCCAC ATACATCAGG GACCTCTCCA TCCATCATAC ATTCTCTCGC 720
TGCGTCACAG TCCATGGCTC CAATGGCTTG TTGATCAAGG ACGTTGTGGG CTATAACTCT 780
TTGGGCCACT GCTTCTTCAC GGAAGATGGG CCGGAGGAAC GCAACACTTT TGACCACTGT 840
CTTGGCCTCC TTGTCAAGTC TGGAACCCTC CTCCCCTCGG ACCGTGACAG CAAGATGTGC 900
AAGATGATCA CAGGAGACTC CTACCCAGGG TACATCCCCA AGCCCAGGCA AGACTGCAAT 960
GCTGTGTCCA CCTTCTGGAT GGCCAATCCC AACAACAACC TCATCAACTG TGCCGCTGCA 1020
GGATCTGAGG AAACTGGATT TTGGTTTATT TTTCACCACG TACCAACGGG CCCCTCCGTG 1080
GGAATGTACT CCCCAGGTTA TTCAGAGCAC ATTCCACTGG GAAAATTCTA TAACAACCGA 1140
GCACATTCCA ACTACCGGGC TGGCATGATC ATAGACAACG GAGTCAAAAC CACCGAGGCC 1200
TCTGCCAAGG ACAAGCGGCC GTTCCTCTCA ATCATCTCTG CCAGATACAG CCCTCACCAG 1260
GACGCCGACC CGCTGAAGCC CCGGGAGCCG GCCATCATCA GACACTTCAT TGCCTACAAG 1320
AACCAGGACC ACGGGGCCTG GCTGCGCGGC GGGGATGTGT GGCTGGACAG CTGCCGGTTT 1380
GCTGACAATG GCATTGGCCT GACCCTGGCC AGTGGTGGAA CCTTCCCGTA TGACGACGGC 1440
TCCAAGCAAG AGATAAAGAA CAGCTTGTTT GTTGGCGAGA GTGGCAACGT GGGGACGGAA 1500
ATGATGGACA ATAGGATCTG GGGCCCTGGC GGCTTGGACC ATAGCGGAAG GACCCTCCCT 1560
ATAGGCCAGA ATTTTCCAAT TAGAGGAATT CAGTTATATG ATGGCCCCAT CAACATCCAA 1620
AACTGCACTT TCCGAAAGTT TGTGGCCCTG GAGGGCCGGC ACACCAGCGC CCTGGCCTTC 1680
CGCCTGAATA ATGCCTGGCA GAGCTGCCCC CATAACAACG TGACCGGCAT TGCCTTTGAG 1740
GACGTTCCGA TTACTTCCAG AGTGTTCTTC GGAGAGCCTG GGCCCTGGTT CAACCAGCTG 1800 GACATGGATG GGGATAAGAC ATCTGTGTTC CATGACGTCG ACGGCTCCGT GTCCGAGTAC 1860
CCTGGCTCCT ACCTCACGAA GAATGACAAC TGGCTGGTCC GGCACCCAGA CTGCATCAAT 1920
GTTCCCGACT GGAGAGGGGC CATTTGCAGT GGGTGCTATG CACAGATGTA CATTCAAGCC 1980
TACAAGACCA GTAACCTGCG AATGAAGATC ATCAAGAATG ACTTCCCCAG CCACCCTCTT 2040
TACCTGGAGG GGGCGCTCAC CAGGAGCACC CATTACCAGC AATACCAACC GGTTGTCACC 2100
CTGCAGAAGG GCTACACCAT CCACTGGGAC CAGACGGCCC CCGCCGAACT CGCCATCTGG 2160
CTCATCAACT TCAACAAGGG CGACTGGATC CGAGTGGGGC TCTGCTACCC GCGAGGCACC 2220
ACATTCTCCA TCCTCTCGGA TGTTCACAAT CGCCTGCTGA AGCAAACGTC CAAGACGGGC 2280
GTCTTCGTGA GGACCTTGCA GATGGACAAA GTGGAGCAGA GCTACCCTGG CAGGAGCCAC 2340
TACTACTGGG ACGAGGACTC AGGGCTGTTG TTCCTGAAGC TGAAAGCTCA GAACGAGAGA 2400
GAGAAGTTTG CTTTCTGCTC CATGAAAGGC TGTGAGAGGA TAAAGATTAA AGCTCTGATT 2460
CCAAAGAACG CAGGCGTCAG TGACTGCACA GCCACAGCTT ACCCCAAGTT CACCGAGAGG 2520
GCTGTCGTAG ACGTGCCGAT GCCCAAGAAG CTCTTTGGTT CTCAGCTGAA AACAAAGGAC 2580
CATTTCTTGG AGGTGAAGAT GGAGAGTTCC AAGCAGCACT TCTTCCACCT CTGGAACGAC 2640
TTCGCTTACA TTGAAGTGGA TGGGAAGAAG TACCCCAGTT CGGAGGATGG CATCCAGGTG 2700
GTGGTGATTG ACGGGAACCA AGGGCGCGTG GTGAGCCACA CGAGCTTCAG GAACTCCATT 2760
CTGCAAGGCA TACCATGGCA GCTTTTCAAC TATGTGGCGA CCATCCCTGA CAATTCCATA 2820
GTGCTTATGG CATCAAAGGG AAGATACGTC TCCAGAGGCC CATGGACCAG AGTGCTGGAA 2880
AAGCTTGGGG CAGACAGGGG TCTCAAGTTG AAAGAGCAAA TGGCATTCGT TGGCTTCAAA 2940
GGCAGCTTCC GGCCCATCTG GGTGACACTG GACACTGAGG ATCACAAAGC CAAAATCTTC 3000
CAAGTTGTGC CCATCCCTGT GGTGAAGAAG AAGAAGTTGT GAGGACAGCT GCCGCCCGGT 3060
GCCACCTCGT GGTAGACTAT GACGGTGACT CTTGGCAGCA GACCAGTGGG GGATGGCTGG 3120
GTCCCCCAGC CCCTGCCAGC AGCTGCCTGG GAAGGCCGTG TTTCAGCCCT GATGGGCCAA 3180
GGGAAGGCTA TCAGAGACCC TGGTGCTGCC ACCTGCCCCT ACTCAAGTGT CTACCTGGAG 3240
CCCCTGGGGC GGTGCTGGCC AATGCTGGAA ACATTCACTT TCCTGCAGCC TCTTGGGTGC 3300
TTCTCTCCTA TCTGTGCCTC TTCAGTGGGG GTTTGGGGAC CATATCAGGA GACCTGGGTT 3360
GTGCTGACAG CAAAGATCCA CTTTGGCAGG AGCCCTGACC CAGCTAGGAG GTAGTCTGGA 3420
GGGCTGGTCA TTCACAGATC CCCATGGTCT TCAGCAGACA AGTGAGGGTG GTAAATGTAG 3480
GAGAAAGAGC CTTGGCCTTA AGGAAATCTT TACTCCTGTA AGCAAGAGCC AACCTCACAG 3540
GATTAGGAGC TGGGGTAGAA CTGGCTATCC TTGGGGAAGA GGCAAGCCCT GCCTCTGGCC 3600
GTGTCCACCT TTCAGGAGAC TTTGAGTGGC AGGTTTGGAC TTGGACTAGA TGACTCTCAA 3660
AGGCCCTTTT AGTTCTGAGA TTCCAGAAAT CTGCTGCATT TCACATGGTA CCTGGAACCC 3720
AACAGTTCAT GGATATCCAC TGATATCCAT GATGCTGGGT GCCCCAGCGC ACACGGGATG 3780
GAGAGGTGAG AACTAATGCC TAGCTTGAGG GGTCTGCAGT CCAGTAGGGC AGGCAGTCAG 3840
GTCCATGTGC ACTGCAATGC CAGGTGGAGA AATCACAGAG AGGTAAAATG GAGGCCAGTG 3900
CCATTTCAGA GGGGAGGCTC AGGAAGGCTT CTTGCTTACA GGAATGAAGG CTGGGGGCAT 3960
TTTGCTGGGG GGAGATGAGG CAGCCTCTGG AATGGCTCAG GGATTCAGCC CTCCCTGCCG 4020
CTGCCTGCTG AAGCTGGTGA CTACGGGGTC GCCCTTTGCT CACGTCTCTC TGGCCCACTC 4080
ATGATGGAGA AGTGTGGTCA GAGGGGAGCA ATGGGCTTTG CTGCTTATGA GCACAGAGGA 4140
ATTCAGTCCC CAGGCAGCCC TGCCTCTGAC TCCAAGAGGG TGAAGTCCAC AGAAGTGAGC 4200
TCCTGCCTTA GGGCCTCATT TGCTCTTCAT CCAGGGAACT GAGCACAGGG GGCCTCCAGG 4260
AGACCCTAGA TGTGCTCGTA CTCCCTCGGC CTGGGATTTC AGAGCTGGAA ATATAGAAAA 4320
TATCTAGCCC AAAGCCTTCA TTTTAACAGA TGGGGAAAGT GAGCCCCCAA GATGGGAAAG 4380
AACCACACAG CTAAGGGAGG GCCTGGGGAG CCCCACCCTA GCCCTTGCTG CCACACCACA 4440
TTGCCTCAAC AACCGGCCCC AGAGTGCCCA GGCACTCCTG AGGTAGCTTC TGGAAATGGG 4500
GACAAGTCCC CTCGAAGGAA AGGAAATGAC TAGAGTAGAA TGACAGCTAG CAGATCTCTT 4560
CCCTCCTGCT CCCAGCGCAC ACAAACCCGC CCTCCCCTTG GTGTTGGCGG TCCCTGTGGC 4620
CTTCACTTTG TTCACTACCT GTCAGCCCAG CCTGGGTGCA CAGTAGCTGC AACTCCCCAT 4680
TGGTGCTACC TGGCTCTCCT GTCTCTGCAG CTCTACAGGT GAGGCCCAGC AGAGGGAGTA 4740
GGGCTCGCCA TGTTTCTGGT GAGCCAATTT GGCTGATCTT GGGTGTCTGA ACAGCTATTG 4800
GGTCCACCCC ACTCCCTTTC AGCTGCTGCT TAATGCCCTG CTCTCTCCCT GGCCCACCTT 4860
ATAGAGAGCC CAAAGAGCTC CTGTAAGAGG GAGAACTCTA TCTGTGGTTT ATAATCTTGC 4920
ACGAGGCACC AGAGTCTCCC TGGGTCTTGT GATGAACTAC ATTTATCCCC TTTCCTGCCC 4980
CAACCACAAA CTCTTTCCTT CAAAGAGGGC CTGCCTGGCT CCCTCCACCC AACTGCACCC 5040
ATGAGACTCG GTCCAAGAGT CCATTCCCCA GGTGGGAGCC AACTGTCAGG GAGGTCTTTC 5100
CCACCAAACA TCTTTCAGCT GCTGGGAGGT GACCATAGGG CTCTGCTTTT AAAGATATGG 5160 CTGCTTCAAA GGCCAGAGTC ACAGGAAGGA CTTCTTCCAG GGAGATTAGT GGTGATGGAG 5220
AGGAGAGTTA AAATGACCTC ATGTCCTTCT TGTCCACGGT TTTGTTGAGT TTTCACTCTT 5280 CTAATGCAAG GGTCTCACAC TGTGAACCAC TTAGGATGTG ATCACTTTCA GGTGGCCAGG 5340 AATGTTGAAT GTCTTTGGCT CAGTTCATTT AAAAAAGATA TCTATTTGAA AGTTCTCAGA 5400 GTTGTACATA TGTTTCACAG TACAGGATCT GTACATAAAA GTTTCTTTCC TAAACCATTC 5460 ACCAAGAGCC AATATCTAGG CATTTTCTTG GTAGCACAAA TTTTCTTATT GCTTAGAAAA 5520 TTGTCCTCCT TGTTATTTCT GTTTGTAAGA CTTAAGTGAG TTAGGTCTTT AAGGAAAGCA 5580 ACGCTCCTCT GAAATGCTTG TCTTTTTTCT GTTGCCGAAA TAGCTGGTCC TTTTTCGGGA 5640 GTTAGATGTA TAGAGTGTTT GTATGTAAAC ATTTCTTGTA GGCATCACCA TGAACAAAGA 5700 TATATTTTCT ATTTATTTAT TATATGTGCA CTTCAAGAAG TCACTGTCAG AGAAATAAAG 5760 AATTGTCTTA AATGTCAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAA
Seq ID NO: 140 Protein sequence Protein Accession ft : XP 051860.2
21 41 51
MDGVNLSTEV VYKKGQDYRF ACYDRGRACR SYRVRFLCGK PVRPKLTVTI DTNVNSTILN 60
LEDNVQSWKP GDTLVIASTD YSMYQAEEFQ VLPCRSCAPN QVKVAGKPMY LHIGEEIDGV 120
DMRAEVGLLS RNIIVMGEME DKCYPYRNHI CNFFDFDTFG GHIKFALGFK AAHLEGTELK 180
HMGQQLVGQY PIHFHLAGDV DERGGYDPPT YIRDLSIHHT FSRCVTVHGS NGLLIKDWG 240
YNSLGHCFFT EDGPEERNTF DHCLGLLVKS GTLLPSDRDS KMCKMITGDS YPGYIPKPRQ 300
DCNAVSTFWM ANPNNNLINC AAAGSEETGF WFIFHHVPTG PSVGMYSPGY SEHIPLGKFY 360
NNRAHSNYRA GMIIDNGVKT TEASAKDKRP FLSIISARYS PHQDADPLKP REPAIIRHFI 420
AYKNQDHGAW LRGGDVWLDS CRFADNGIGL TLASGGTFPY DDGΞKQEIKN SLFVGESGNV 480
GTEMMDNRIW GPGGLDHSGR TLPIGQNFPI RGIQLYDGPI NIQNCTFRKF VALEGRHTSA 540
LAFRLNNAWQ SCPHNNVTGI AFEDVPITSR VFFGEPGPWF NQLDMDGDKT SVFHDVDGSV 600 SEYPGSYLTK NDNWLVRHPD CINVPDWRGA ICSGCYAQMY IQAYKTSNLR MKIIKNDFPS 660 HPLYLEGALT RSTHYQQYQP WTLQKGYTI HWDQTAPAEL AIWLINFNKG DWIRVGLCYP 720 RGTTFSILSD VHNRLLKQTS KTGVFVRTLQ MDKVEQSYPG RSHYYWDEDS GLLFLKLKAQ 780 NEREKFAFCS MKGCERIKIK ALIPKNAGVS DCTATAYPKF TERAWDVPM PKKLFGSQLK 840 TKDHFLEVKM ESSKQHFFHL WNDFAYIEVD GKKYPSSEDG IQVWIDGNQ GRWSHTSFR 900 NSILQGIPWQ LFNYVATIPD NSIVLMASKG RYVSRGPWTR VLEKLGADRG LKLKEQMAFV 960 GFKGSFRPIW VTLDTEDHKA KIFQWPIPV VKKKKL
Seq ID NO: 141 DNA sequence Nucleic Acid Accession ft: Eos εequence Coding sequence: 261..2861
1 11 21 31 41 51
I I I I I I
GAGCTAGCGC TCAAGCAGAG CCCAGCGCGG TGCTATCGGA CAGAGCCTGG CGAGCGCAAG 60
CGGCGCGGGG AGCCAGCGGG GCTGAGCGCG GCCAGGGTCT GAACCCAGAT TTCCCAGACT 120
AGCTACCACT CCGCTTGCCC ACGCCCCGGG AGCTCGCGGC GCCTGGCGGT CAGCGACCAG 180
ACGTCCGGGG CCGCTGCGCT CCTGGCCCGC GAGGCGTGAC ACTGTCTCGG CTACAGACCC 240
AGAGGGAGCA CACTGCCAGG ATGGGAGCTG CTGGGAGGCA GGACTTCCTC TTCAAGGCCA 300
TGCTGACCAT CAGCTGGCTC ACTCTGACCT GCTTCCCTGG GGCCACATCC ACAGTGGCTG 360
CTGGGTGCCC TGACCAGAGC CCTGAGTTGC AACCCTGGAA CCCTGGCCAT GACCAAGACC 420
ACCATGTGCA TATCGGCCAG GGCAAGACAC TGCTGCTCAC CTCTTCTGCC ACGGTCTATT 480
CCATCCACAT CTCAGAGGGA GGCAAGCTGG TCATTAAAGA CCACGACGAG CCGATTGTTT 540
TGCGAACCCG GCACATCCTG ATTGACAACG GAGGAGAGCT GCATGCTGGG AGTGCCCTCT 600
GCCCTTTCCA GGGCAATTTC ACCATCATTT TGTATGGAAG GGCTGATGAA GGTATTCAGC 660
CGGATCCTTA CTATGGTCTG AAGTACATTG GGGTTGGTAA AGGAGGCGCT CTTGAGTTGC 720
ATGGACAGAA AAAGCTCTCC TGGACATTTC TGAACAAGAC CCTTCACCCA GGTGGCATGG 780
CAGAAGGAGG CTATTTTTTT GAAAGGAGCT GGGGCCACCG TGGAGTTATT GTTCATGTCA 840
TCGACCCCAA ATCAGGCACA GTCATCCATT CTGACCGGTT TGACACCTAT AGATCCAAGA 900
AAGAGAGTGA ACGTCTGGTC CAGTATTTGA ACGCGGTGCC CGATGGCAGG ATCCTTTCTG 960
TTGCAGTGAA TGATGAAGGT TCTCGAAATC TGGATGACAT GGCCAGGAAG GCGATGACCA 1020
AATTGGGAAG CAAACACTTC CTGCACCTTG GATTTAGACA CCCTTGGAGT TTTCTAACTG 1080
TGAAAGGAAA TCCATCATCT TCAGTGGAAG ACCATATTGA ATATCATGGA CATCGAGGCT 1140
CTGCTGCTGC CCGGGTATTC AAATTGTTCC AGACAGAGCA TGGCGAATAT TTCAATGTTT 1200
CTTTGTCCAG TGAGTGGGTT CAAGACGTGG AGTGGACGGA GTGGTTCGAT CATGATAAAG 1260
TATCTCAGAC TAAAGGTGGG GAGAAAATTT CAGACCTCTG GAAAGCTCAC CCAGGAAAAA 1320
TATGCAATCG TCCCATTGAT ATACAGGCCA CTACAATGGA TGGAGTTAAC CTCAGCACCG 1380
AGGTTGTCTA CAAAAAAGGC CAGGATTATA GGTTTGCTTG CTACGACCGG GGCAGAGCCT 1440
GCCGGAGCTA CCGTGTACGG TTCCTCTGTG GGAAGCCTGT GAGGCCCAAA CTCACAGTCA 1500
CCATTGACAC CAATGTGAAC AGCACCATTC TGAACTTGGA GGATAATGTA CAGTCATGGA 1560
AACCTGGAGA TACCCTGGTC ATTGCCAGTA CTGATTACTC CATGTACCAG GCAGAAGAGT 1620
TCCAGGTGCT TCCCTGCAGA TCCTGCGCCC CCAACCAGGT CAAAGTGGCA GGGAAACCAA 1680
TGTACCTGCA CATCGGGGAG GAGATAGACG GCGTGGACAT GCGGGCGGAG GTTGGGCTTC 1740
TGAGCCGGAA CATCATAGTG ATGGGGGAGA TGGAGGACAA ATGCTACCCC TACAGAAACC 1800
ACATCTGCAA TTTCTTTGAC TTCGATACCT TTGGGGGCCA CATCAAGTTT GCTCTGGGAT 1860
TTAAGGCAGC ACACTTGGAG GGCACGGAGC TGAAGCATAT GGGACAGCAG CTGGTGGGTC 1920
AGTACCCGAT TCACTTCCAC CTGGCCGGTG ATGTAGACGA AAGGGGAGGT TATGACCCAC 1980
CCACATACAT CAGGGACCTC TCCATCCATC ATACATTCTC TCGCTGCGTC ACAGTCCATG 2040
GCTCCAATGG CTTGTTGATC AAGGACGTTG TGGGCTATAA CTCTTTGGGC CACTGCTTCT 2100
TCACGGAAGA TGGGCCGGAG GAACGCAACA CTTTTGACCA CTGTCTTGGC CTCCTTGTCA 2160
AGTCTGGAAC CCTCCTCCCC TCGGACCGTG ACAGCAAGAT GTGCAAGATG ATCACAGAGG 2220
ACTCCTACCC AGGGTACATC CCCAAGCCCA GGCAAGACTG CAATGCTGTG TCCACCTTCT 2280
GGATGGCCAA TCCCAACAAC AACCTCATCA ACTGTGCCGC TGCAGGATCT GAGGAAACTG 2340
GATTTTGGTT TATTTTTCAC CACGTACCAA CGGGCCCCTC CGTGGGAATG TACTCCCCAG 2400
GTTATTCAGA GCACATTCCA CTGGGAAAAT TCTATAACAA CCGAGCACAT TCCAACTACC 2460
GGGCTGGCAT GATCATAGAC AACGGAGTCA AAACCACCGA GGCCTCTGCC AAGGACAAGC 2520
GGCCGTTCCT CTCAATCATC TCTGCCAGAT ACAGCCCTCA CCAGGACGCC GACCCGCTGA 2580
AGCCCCGGGA GCCGGCCATC ATCAGACACT TCATTGCCTA CAAGAACCAG GACCACGGGG 2640
CCTGGCTGCG CGGCGGGGAT GTGTGGCTGG ACAGCTGCCA TTTCAGAGGG GAGGCTCAGG 2700
AAGGCTTCTT GCTTACAGGA ATGAAGGCTG GGGGCATTTT GCTGGGGGGA GATGAGGCAG 2760
CCTCTGGAAT GGCTCAGGGA TTCAGCCCTC CCTGCCGCTG CCTGCTGAAG CTGGTGACTA 2820
CGGGGTCGCC CTTTGCTCAC GTCTCTCTGG CCCACTCATG ATGGAGAAGT GTGGTCAGAG 2880
GGGAGCAATG GGCTTTGCTG CTTATGAGCA CAGAGGAATT CAGTCCCCAG GCAGCCCTGC 2940
CTCTGACTCC AAGAGGGTGA AGTCCACAGA AGTGAGCTCC TGCCTTAGGG CCTCATTTGC 3000
TCTTCATCCA GGGAACTGAG CACAGGGGGC CTCCAGGAGA CCCTAGATGT GCTCGTACTC 3060
CCTCGGCCTG GGATTTCAGA GCTGGAAATA TAGAAAATAT CTAGCCCAAA GCCTTCATTT 3120
TAACAGATGG GGAAAGTGAG CCCCCAAGAT GGGAAAGAAC CACACAGCTA AGGGAGGGCC 3180
TGGGGAGCCC CACCCTAGCC CTTGCTGCCA CACCACATTG CCTCAACAAC CGGCCCCAGA 3240
GTGCCCAGGC ACTCCTGAGG TAGCTTCTGG AAATGGGGAC AAGTCCCCTC GAAGGAAAGG 3300
AAATGACTAG AGTAGAATGA CAGCTAGCAG ATCTCTTCCC TCCTGCTCCC AGCGCACACA 3360
AACCCGCCCT CCCCTTGGTG TTGGCGGTCC CTGTGGCCTT CACTTTGTTC ACTACCTGTC 3420
AGCCCAGCCT GGGTGCACAG TAGCTGCAAC TCCCCATTGG TGCTACCTGG CTCTCCTGTC 3480
TCTGCAGCTC TACAGGTGAG GCCCAGCAGA GGGAGTAGGG CTCGCCATGT TTCTGGTGAG 3540
CCAATTTGGC TGATCTTGGG TGTCTGAACA GCTATTGGGT CCACCCCAGT CCCTTTCAGC 3600
TGCTGCTTAA TGCCCTGCTC TCTCCCTGGC CCACCTTATA GAGAGCCCAA AGAGCTCCTG 3660
TAAGAGGGAG AACTCTATCT GTGGTTTATA ATCTTGCACG AGGCACCAGA GTCTCCCTGG 3720
GTCTTGTGAT GAACTACATT TATCCCCTTT CCTGCCCCAA CCACAAACTC TTTCCTTCAA 3780
AGAGGGCCTG CCTGGCTCCC TCCACCCAAC TGCACCCATG AGACTCGGTC CAAGAGTCCA 3840
TTCCCCAGGT GGGAGCCAAC TGTCAGGGAG GTCTTTCCCA CCAAACATCT TTCAGCTGCT 3900
GGGAGGTGAC CATAGGGCTC TGCTTTTAAA GATATGGCTG CTTCAAAGGC CAGAGTCACA 3960
GGAAGGACTT CTTCCAGGGA GATTAGTGGT GATGGAGAGG AGAGTTAAAA TGACCTCATG 4020
TCCTTCTTGT CCACGGTTTT GTTGAGTTTT CACTCTTCTA ATGCAAGGGT CTCACACTGT 4080
GAACCACTTA GGATGTGATC ACTTTCAGGT GGCCAGGAAT GTTGAATGTC TTTGGCTCAG 4140
TTCATTTAAA AAAGATATCT ATTTGAAAGT TCTCAGAGTT GTACATATGT TTCACAGTAC 4200 AGGATCTGTA CATAAAAGTT TCTTTCCTAA ACCATTCACC AAGAGCCAAT ATCTAGGCAT 4260 TTTCTTGGTA GCACAAATTT TCTTATTGCT TAGAAAATTG TCCTCCTTGT TATTTCTGTT 4320 TGTAAGACTT AAGTGAGTTA GGTCTTTAAG GAAAGCAACG CTCCTCTGAA ATGCTTGTCT 4380 TTTTTCTCTT GCCGAAATAG CTGGTCCTTT TTCGGGAGTT AGATGTATAG AGTGTTTGTA 4440 TGTAAACATT TCTTGTAGGC ATCACCATGA ACAAAGATAT ATTTTCTATT TATTTATTAT 4500 ATGTGCACTT CAAGAAGTCA CTGTCAGAGA AATAAAGAAT TGTCTTAAAT GTCATGATTG 4560 GAGATGTCCT TTGCATTGCT TGGAAGGGGT GTACCTAGAG CCAAGGAAAT TGGCTCTGGT 4620 TTGGAAAAAT TTTGCTGTTA TTATAGTAAA CATACAAAGG ATGTCAAAAA AAAAAAAAAA 4680 AAAAAAAAAA AAAAAAAAAA AA
Seq ID NO: 142 Protein εequence Protein Acceεsion ft: Eos sequence
11 21 31 41 51
I I I I
MGAAGRQDFL FKAMLTISWL TLTCFPGATS TVAAGCPDQS PELQPWNPGH D 1QDHHVHIGQ 60 GKTLLLTSSA TVYSIHISEG GKLVIKDHDE PIVLRTRHIL IDNGGELHAG SALCPFQGNF 120 TIILYGRADE GIQPDPYYGL KYIGVGKGGA LELHGQKKLS WTFLNKTLHP GGMAEGGYFF 180 ERSWGHRGVI VHVIDPKSGT VIHSDRFDTY RSKKESERLV QYLNAVPDGR ILSVAVNDEG 240 SRNLDDMARK AMTKLGSKHF LHLGFRHPWS FLTVKGNPSS SVEDHIEYHG HRGSAAARVF 300 KLFQTEHGEY FNVSLSSEWV QDVEWTEWFD HDKVSQTKGG EKISDLWKAH PGKICNRPID 360 IQATTMDGVN LSTEWYKKG QDYRFACYDR GRACRSYRVR FLCGKPVRPK LTVTIDTNVN 420 STILNLEDNV QSWKPGDTLV IASTDYSMYQ AEEFQVLPCR SCAPNQVKVA GKPMYLHIGE 480 EIDGVDMRAE VGLLSRNIIV MGEMEDKCYP YRNHICNFFD FDTFGGHIKF ALGFKAAHLE 540 GTELKHMGQQ LVGQYPIHFH LAGDVDERGG YDPPTYIRDL SIHHTFSRCV TVHGSNGLLI 600 KDWGYNSLG HCFFTEDGPE ERNTFDHCLG LLVKSGTLLP SDRDSKMCKM ITEDSYPGYI 660 PKPRQDCNAV STFWMANPNN NLINCAAAGS EETGFWFIFH HVPTGPSVGM YSPGYSEHIP 720 LGKFYNNRAH SNYRAGMIID NGVKTTEASA KDKRPFLSII SARYSPHQDA DPLKPREPAI 780 IRHFIAYKNQ DHGAWLRGGD VWLDSCHFRG EAQEGFLLTG MKAGGILLGG DEAASGMAQG 840 FSPPCRCLLK LVTTGSPFAH VSLAHS
Seq ID NO: 143 NM DNA sequence Nucleic Acid Accession ft: NM_006017 Coding sequence: 38.-2635
1 11 21 31
I
CCAAGTTCTA CCTCATGTTT GGAGGATCTT GCTAGCTATG GCCCTCGTAC TCGGCTCCCT 60
GTTGCTGCTG GGGCTGTGCG GGAACTCCTT TTCAGGAGGG CAGCCTTCAT CCACAGATGC 120
TCCTAAGGCT TGGAATTATG AATTGCCTGC AACAAATTAT GAGACCCAAG ACTCCCATAA 180
AGCTGGACCC ATTGGCATTC TCTTTGAACT AGTGCATATC TTTCTCTATG TGGTACAGCC 240
GCGTGATTTC CCAGAAGATA CTTTGAGAAA ATTCTTACAG AAGGCATATG AATCCAAAAT 300
TGATTATGAC AAGCCAGAAA CTGTAATCTT AGGTCTAAAG ATTGTCTACT ATGAAGCAGG 360
GATTATTCTA TGCTGTGTCC TGGGGCTGCT GTTTATTATT CTGATGCCTC TGGTGGGGTA 420
TTTCTTTTGT ATGTGTCGTT GCTGTAACAA ATGTGGTGGA GAAATGCACC AGCGACAGAA 480
GGAAAATGGG CCCTTCCTGA GGAAATGCTT TGCAATCTCC CTGTTGGTGA TTTGTATAAT 540
AATAAGCATT GGCATCTTCT ATGGTTTTGT GGCAAATCAC CAGGTAAGAA CCCGGATCAA 600
AAGGAGTCGG AAACTGGCAG ATAGCAATTT CAAGGACTTG CGAACTCTCT TGAATGAAAC 660
TCCAGAGCAA ATCAAATATA TATTGGCCCA GTACAACACT ACCAAGGACA AGGCGTTCAC 720
AGATCTGAAC AGTATCAATT CAGTGCTAGG AGGCGGAATT CTTGACCGAC TGAGACCCAA 780
CATCATCCCT GTTCTTGATG AGATTAAGTC CATGGCAACA GCGATCAAGG AGACCAAAGA 840
GGCGTTGGAG AACATGAACA GCACCTTGAA GAGCTTGCAC CAACAAAGTA CACAGCTTAG 900
CAGCAGTCTG ACCAGCGTGA AAACTAGCCT GCGGTCATCT CTCAATGACC CTCTGTGCTT 960
GGTGCATCCA TCAAGTGAAA CCTGCAACAG CATCAGATTG TCTCTAAGCC AGCTGAATAG 1020
CAACCCTGAA CTGAGGCAGC TTCCACCCGT GGATGCAGAA CTTGACAACG TTAATAACGT 1080
TCTTAGGACA GATTTGGATG GCCTGGTCCA ACAGGGCTAT CAATCCCTTA ATGATATACC 1140
TGACAGAGTA CAACGCCAAA CCACGACTGT CGTAGCAGGT ATCAAAAGGG TCTTGAATTC 1200
CATTGGTTCA GATATCGACA ATGTAACTCA GCGTCTTCCT ATTCAGGATA TACTCTCAGC 1260
ATTCTCTGTT TATGTTAATA ACACTGAAAG TTACATCCAC AGAAATTTAC CTACATTGGA 1320
AGAGTATGAT TCATACTGGT GGCTGGGTGG CCTGGTCATC TGCTCTCTGC TGACCCTCAT 1380
CGTGATTTTT TACTACCTGG GCTTACTGTG TGGCGTGTGC GGCTATGACA GGCATGCCAC 1440
CCCGACCACC CGAGGCTGTG TCTCCAACAC CGGAGGCGTC TTCCTCATGG TTGGAGTTGG 1500
ATTAAGTTTC CTCTTTTGCT GGATATTGAT GATCATTGTG GTTCTTACCT TTGTCTTTGG 1560
TGCAAATGTG GAAAAACTGA TCTGTGAACC TTACACGAGC AAGGAATTAT TCCGGGTTTT 1620
GGATACACCC TACTTACTAA ATGAAGACTG GGAATACTAT CTCTCTGGGA AGCTATTTAA 1680
TAAATCAAAA ATGAAGCTCA CTTTTGAACA AGTTTACAGT GACTGCAAAA AAAATAGAGG 1740
CACTTACGGC ACTCTTCACC TGCAGAACAG CTTCAATATC AGTGAACATC TCAACATTAA 1800
TGAGCATACT GGAAGCATAA GCAGTGAATT GGAAAGTCTG AAGGTAAATC TTAATATCTT 1860
TCTGTTGGGT GCAGCAGGAA GAAAAAACCT TCAGGATTTT GCTGCTTGTG GAATAGACAG 1920
AATGAATTAT GACAGCTACT TGGCTCAGAC TGGTAAATCC CCCGCAGGAG TGAATCTTTT 1980
ATCATTTGCA TATGATCTAG AAGCAAAAGC AAACAGTTTG CCCCCAGGAA ATTTGAGGAA 2040
CTCCCTGAAA AGAGATGCAC AAACTATTAA AACAATTCAC CAGCAACGAG TCCTTCCTAT 2100
AGAACAATCA CTGAGCACTC TATACCAAAG CGTCAAGATA CTTCAACGCA CAGGGAATGG 2160
ATTGTTGGAG AGAGTAACTA GGATTCTAGC TTCTCTGGAT TTTGCTCAGA ACTTCATCAC 2220
AAACAATACT TCCTCTGTTA TTATTGAGGA AACTAAGAAG TATGGGAGAA CAATAATAGG 2280
ATATTTTGAA CATTATCTGC AGTGGATCGA GTTCTCTATC AGTGAGAAAG TGGCATCGTG 2340
CAAACCTGTG GCCACCGCTC TAGATACTGC TGTTGATGTC TTTCTGTGTA GCTACATTAT 2400
CGACCCCTTG AATTTGTTTT GGTTTGGCAT AGGAAAAGCT ACTGTATTTT TACTTCCGGC 2460
TCTAATTTTT GCGGTAAAAC TGGCTAAGTA . CTATCGTCGA ATGGATTCGG AGGACGTGTA 2520
CGATGATGTT GAAACTATAC CCATGAAAAA . TATGGAAAAT GGTAATAATG GTTATCATAA 2580
AGATCATGTA TATGGTATTC ACAATCCTGT TATGACAAGC CCATCACAAC ATTGATAGCT 2640
GATGTTGAAA CTGCTTGAGC ATCAGGATAC : TCAAAGTGGA AAGGATCACA GATTTTTGGT 2700
AGTTTCTGGG TCTACAAGGA CTTTCCAAAT ' CCAGGAGCAA CGCCAGTGGC AACGTAGTGA 2760
CTCAGGCGGG CACCAAGGCA ACGGCACCAT ' TGGTCTCTGG GTAGTGCTTT AAGAATGAAC 2820 ACAATCACGT TATAGTCCAT GGTCCATCAC TATTCAAGGA TGACTCCCTC CCTTCCTGTC 2880 TATTTTTGTT TTTTACTTTT TTACACTGAG TTTCTATTTA GACACTACAA CATATGGGGT 2940 GTTTGTTCCC ATTGGATGCA TTTCTATCAA AACTCTATCA AATGTGATGG CTAGATTCTA 3000 ACATATTGCC ATGTGTGGAG TGTGCTGAAC ACACACCAGT TTACAGGAAA GATGCATTTT 3060 GTGTACAGTA AACGGTGTAT ATACCTTTTG TTACCACAGA GTTTTTTAAA CAAATGAGTA 3120 TTATAGGACT TTCTTCTAAA TGAGCTAAAT AAGTCACCAT TGACTTCTTG GTGCTGTTGA 3180 AAATAATCCA TTTTCACTAA AAGTGTGTGA AACCTACAGC ATATTCTTCA CGCAGAGATT 3240 TTCATCTATT ATACTTTATC AAAGATTGGC CATGTTCCAC TTGGAAATGG CATGCAAAAG 3300 CCATCATAGA GAAACCTGCG TAACTCCATC TGACAAATTC AAAAGAGAGA GAGAGATCTT 3360 GAGAGAGAAA TGCTGTTCGT TCAAAAGTGG AGTTGTTTTA ACAGATGCCA ATTACGGTGT 3420 ACAGTTTAAC AGAGTTTTCT GTTGCATTAG GATAAACATT AATTGGAGTG CAGCTAACAT 3480 GAGTATCATC AGACTAGTAT CAAGTGTTCT AAAATGAAAT ATGAGAAGAT CCTGTCACAA 3540 TTCTTAGATC TGGTGTCCAG CATGGATGAA ACCTTTGAGT TTGGTCCCTA AATTTGCATG 3600 AAAGCACAAG GTAAATATTC ATTTGCTTCA GGAGTTTCAT GTTGGATCTG TCATTATCAA 3660 AAGTGATCAG CAATGAAGAA CTGGTCGGAC AAAATTTAAC GTTGATGTAA TGGAATTCCA 3720 GATGTAGGCA TTCCCCCCAG GTCTTTTCAT GTGCAGATTG CAGTTCTGAT TCATTTGAAT 3780 AAAAAGGAAC TTGG
Seq ID NO: 144 NP Protein sequence Protein Accesεion ft : NP 006008.1
11 21 31 41 51
MALVLGSLLL LGLCGNSFSG GQPSSTDAPK AWNYELPATN YETQDSHKAG PIGILFELVH 60 IFLYWQPRD FPEDTLRKFL QKAYESKIDY DKPETVILGL KIVYYEAGII LCCVLGLLFI 120 ILMPLVGYFF CMCRCCNKCG GEMHQRQKEN GPFLRKCFAI SLLVICIIIS IGIFYGFVAN 180 HQVRTRIKRS RKLADSNFKD LRTLLNETPE QIKYILAQYN TTKDKAFTDL NSINSVLGGG 240 ILDRLRPNII PVLDEIKSMA TAIKETKEAL ENMNSTLKSL HQQSTQLSSS LTSVKTSLRS 300 SLNDPLCLVH PSSETCNSIR LSLSQLNSNP ELRQLPPVDA ELDNVNNVLR TDLDGLVQQG 360 YQSLNDIPDR VQRQTTTWA GIKRVLNSIG SDIDNVTQRL PIQDILSAFS VYVNNTESYI 420 HRNLPTLEEY DSYWWLGGLV ICSLLTLIVI FYYLGLLCGV CGYDRHATPT TRGCVSNTGG 480 VFLMVGVGLS FLFCWILMII WLTFVFGAN VEKLICEPYT SKELFRVLDT PYLLNEDWEY 540 YLSGKLFNKS KMKLTFEQVY SDCKKNRGTY GTLHLQNSFN ISEHLNINEH TGSISSELES 600 LKVNLNIFLL GAAGRKNLQD FAACGIDRMN YDSYLAQTGK SPAGVNLLSF AYDLEAKANS 660 LPPGNLRNSL KRDAQTIKTI HQQRVLPIEQ SLSTLYQSVK I QRTGNGLL ERVTRILASL 720 DFAQNFITNN TSSVIIEETK KYGRTIIGYF EHYLQWIEFS ISEKVASCKP VATALDTAVD 780 VFLCSYIIDP LNLFWFGIGK ATVFLLPALI FAVKLAKYYR RMDSEDVYDD VETIPMKNME 840 NGNNGYHKDH VYGIHNPVMT SPSQH
Seq ID NO: 145 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 38..2605
11 21 31 41
I I I I
CCAAGTTCTA C ICTCATGTTT GGAGGATCTT GCTAGCTATG GCCCTCGTAC TCGGCTCCCT 60
GTTGCTGCTG GGGCTGTGCG GGAACTCCTT TTCAGGAGGG CAGCCTTCAT CCACAGATGC 120
TCCTAAGGCT TGGAATTATG AATTGCCTGC AACAAATTAT GAGACCCAAG ACTCCCATAA 180
AGCTGGACCC ATTGGCATTC TCTTTGAACT AGTGCATATC TTTCTCTATG TGGTACAGCC 240
GCGTGATTTC CCAGAAGATA CTTTGAGAAA ATTCTTACAG AAGGCATATG AATCCAAAAT 300
TGATTATGAC ATTGTCTACT ATGAAGCAGG GATTATTCTA TGCTGTGTCC TGGGGCTGCT 360
GTTTATTATT CTGATGCCTC TGGTGGGGTA TTTCTTTTGT ATGTGTCGTT GCTGTAACAA 420
ATGTGGTGGA GAAATGCACC AGCGACAGAA GGAAAATGGG CCCTTCCTGA GGAAATGCTT 480
TGCAATCTCC CTGTTGGTGA TTTGTATAAT AATAAGCATT GGCATCTTCT ATGGTTTTGT 540
GGCAAATCAC CAGGTAAGAA CCCGGATCAA AAGGAGTCGG AAACTGGCAG ATAGCAATTT 600
CAAGGACTTG CGAACTCTCT TGAATGAAAC TCCAGAGCAA ATCAAATATA TATTGGCCCA 660
GTACAACACT ACCAAGGACA AGGCGTTCAC AGATCTGAAC AGTATCAATT CAGTGCTAGG 720
AGGCGGAATT CTTGACCGAC TGAGACCCAA CATCATCCCT GTTCTTGATG AGATTAAGTC 780
CATGGCAACA GCGATCAAGG AGACCAAAGA GGCGTTGGAG AACATGAACA GCACCTTGAA 840
GAGCTTGCAC CAACAAAGTA CACAGCTTAG CAGCAGTCTG ACCAGCGTGA AAACTAGCCT 900
GCGGTCATCT CTCAATGACC CTCTGTGCTT GGTGCATCCA TCAAGTGAAA CCTGCAACAG 960
CATCAGATTG TCTCTAAGCC AGCTGAATAG CAACCCTGAA CTGAGGCAGC TTCCACCCGT 1020
GGATGCAGAA CTTGACAACG TTAATAACGT TCTTAGGACA GATTTGGATG GCCTGGTCCA 1080
ACAGGGCTAT CAATCCCTTA ATGATATACC TGACAGAGTA CAACGCCAAA CCACGACTGT 1140
CGTAGCAGGT ATCAAAAGGG TCTTGAATTC CATTGGTTCA GATATCGACA ATGTAACTCA 1200
GCGTCTTCCT ATTCAGGATA TACTCTCAGC ATTCTCTGTT TATGTTAATA ACACTGAAAG 1260
TTACATCCAC AGAAATTTAC CTACATTGGA AGAGTATGAT TCATACTGGT GGCTGGGTGG 1320
CCTGGTCATC TGCTCTCTGC TGACCCTCAT CGTGATTTTT TACTACCTGG GCTTACTGTG 1380
TGGCGTGTGC GGCTATGACA GGCATGCCAC CCCGACCACC CGAGGCTGTG TCTCCAACAC 1440
CGGAGGCGTC TTCCTCATGG TTGGAGTTGG ATTAAGTTTC CTCTTTTGCT GGATATTGAT 1500
GATCATTGTG GTTCTTACCT TTGTCTTTGG TGCAAATGTG GAAAAACTGA TCTGTGAACC 1560
TTACACGAGC AAGGAATTAT TCCGGGTTTT GGATACACCC TACTTACTAA ATGAAGACTG 1620
GGAATACTAT CTCTCTGGGA AGCTATTTAA TAAATCAAAA ATGAAGCTCA CTTTTGAACA 1680
AGTTTACAGT GACTGCAAAA AAAATAGAGG CACTTACGGC ACTCTTCACC TGCAGAACAG 1740
CTTCAATATC AGTGAACATC TCAACATTAA TGAGCATACT GGAAGCATAA GCAGTGAATT 1800
GGAAAGTCTG AAGGTAAATC TTAATATCTT TCTGTTGGGT GCAGCAGGAA GAAAAAACCT 1860
TCAGGATTTT GCTGCTTGTG GAATAGACAG AATGAATTAT GACAGCTACT TGGCTCAGAC 1920
TGGTAAATCC CCCGCAGGAG TGAATCTTTT ATCATTTGCA TATGATCTAG AAGCAAAAGC 1980
AAACAGTTTG CCCCCAGGAA ATTTGAGGAA CTCCCTGAAA AGAGATGCAC AAACTATTAA 2040
AACAATTCAC CAGCAACGAG TCCTTCCTAT AGAACAATCA CTGAGCACTC TATACCAAAG 2100
CGTCAAGATA CTTCAACGCA CAGGGAATGG ATTGTTGGAG AGAGTAACTA GGATTCTAGC 2160
TTCTCTGGAT TTTGCTCAGA ACTTCATCAC AAACAATACT TCCTCTGTTA TTATTGAGGA 2220
AACTAAGAAG TATGGGAGAA CAATAATAGG ATATTTTGAA CATTATCTGC AGTGGATCGA 2280
GTTCTCTATC AGTGAGAAAG TGGCATCGTG CAAACCTGTG GCCACCGCTC TAGATACTGC 2340 TGTTGATGTC TTTCTGTGTA GCTACATTAT CGACCCCTTG AATTTGTTTT GGTTTGGCAT 2400 AGGAAAAGCT ACTGTATTTT TACTTCCGGC TCTAATTTTT GCGGTAAAAC TGGCTAAGTA 2460 CTATCGTCGA ATGGATTCGG AGGACGTGTA CGATGATGTT GAAACTATAC CCATGAAAAA 2520 TATGGAAAAT GGTAATAATG GTTATCATAA AGATCATGTA TATGGTATTC ACAATCCTGT 2580 TATGACAAGC CCATCACAAC ATTGATAGCT GATGTTGAAA CTGCTTGAGC ATCAGGATAC 2640 TCAAAGTGGA AAGGATCACA GATTTTTGGT AGTTTCTGGG TCTACAAGGA CTTTCCAAAT 2700 CCAGGAGCAA CGCCAGTGGC AACGTAGTGA CTCAGGCGGG CACCAAGGCA ACGGCACCAT 2760 TGGTCTCTGG GTAGTGCTTT AAGAATGAAC ACAATCACGT TATAGTCCAT GGTCCATCAC 2820 TATTCAAGGA TGACTCCCTC CCTTCCTGTC TATTTTTGTT TTTTACTTTT TTACACTGAG 2880 TTTCTATTTA GACACTACAA CATATGGGGT GTTTGTTCCC ATTGGATGCA TTTCTATCAA 2940 AACTCTATCA AATGTGATGG CTAGATTCTA ACATATTGCC ATGTGTGGAG TGTGCTGAAC 3000 ACACACCAGT TTACAGGAAA GATGCATTTT GTGTACAGTA AACGGTGTAT ATACCTTTTG 3060 TTACCACAGA GTTTTTTAAA CAAATGAGTA TTATAGGACT TTCTTCTAAA TGAGCTAAAT 3120 AAGTCACCAT TGACTTCTTG GTGCTGTTGA AAATAATCCA TTTTCACTAA AAGTGTGTGA 3180 AACCTACAGC ATATTCTTCA CGCAGAGATT TTCATCTATT ATACTTTATC AAAGATTGGC 3240 CATGTTCCAC TTGGAAATGG CATGCAAAAG CCATCATAGA GAAACCTGCG TAACTCCATC 3300 TGACAAATTC AAAAGAGAGA GAGAGATCTT GAGAGAGAAA TGCTGTTCGT TCAAAAGTGG 3360 AGTTGTTTTA ACAGATGCCA ATTACGGTGT ACAGTTTAAC AGAGTTTTCT GTTGCATTAG 3420 GATAAACATT AATTGGAGTG CAGCTAACAT GAGTATCATC AGACTAGTAT CAAGTGTTCT 3480 AAAATGAAAT ATGAGAAGAT CCTGTCACAA TTCTTAGATC TGGTGTCCAG CATGGATGAA 3540 ACCTTTGAGT TTGGTCCCTA AATTTGCATG AAAGCACAAG GTAAATATTC ATTTGCTTCA 3600 GGAGTTTCAT GTTGGATCTG TCATTATCAA AAGTGATCAG CAATGAAGAA CTGGTCGGAC 3660 AAAATTTAAC GTTGATGTAA TGGAATTCCA GATGTAGGCA TTCCCCCCAG GTCTTTTCAT 3720 GTGCAGATTG CAGTTCTGAT TCATTTGAAT AAAAAGGAAC TTGG
Seq ID NO: 146 Protein sequence Protein Accession it:
11 21 31 41 51
I I I
MALVLGSLLL LGLCGNSFSG GQPSSTDAPK AWNYELPATN YETQDSHKAG PIGILFELVH 60 IFLYWQPRD FPEDTLRKFL QKAYESKIDY DIVYYEAGII LCCVLGLLFI ILMPLVGYFF 120 CMCRCCNKCG GEMHQRQKEN GPFLRKCFAI SLLVICIIIS IGIFYGFVAN HQVRTRIKRS 180 RKLADSNFKD LRTLLNETPE QIKYILAQYN TTKDKAFTDL NSINSVLGGG I DRLRPNII 240 PVLDEIKSMA TAIKETKEAL ENMNSTLKSL HQQSTQLSSS LTSVKTSLRS SLNDPLCLVH 300 PSSETCNSIR LSLSQLNSNP ELRQLPPVDA ELDNVNNVLR TDLDGLVQQG YQSLNDIPDR 360 VQRQTTTWA GIKRVLNSIG SDIDNVTQRL PIQDILSAFS VYVNNTESYI HRNLPTLEEY 420 DSYWWLGGLV ICSLLTLIVI FYYLGLLCGV CGYDRHATPT TRGCVSNTGG VFLMVGVGLS 480 FLFCWILMII WLTFVFGAN VEKLICEPYT SKELFRVLDT PYLLNEDWEY YLSGKLFNKS 540 KMKLTFEQVY SDCKKNRGTY GTLHLQNSFN ISEHLNINEH TGSISSELES LKVNLNIFLL 600 GAAGRKNLQD FAACGIDRMN YDSYLAQTGK SPAGVNLLSF AYDLEAKANS LPPGNLRNSL 660 KRDAQTIKTI HQQRVLPIEQ SLSTLYQSVK ILQRTGNGLL ERVTRILASL DFAQNFITNN 720 TSSVIIEETK KYGRTIIGYF EHYLQWIEFS ISEKVASCKP VATALDTAVD VFLCSYIIDP 780 LNLFWFGIGK ATVFLLPALI FAVKLAKYYR RMDSEDVYDD VETIPMKNME NGNNGYHKDH 840 VYGIHNPVMT SPSQH
Seq ID NO: 147 DNA sequence
Nucleic Acid Accession ft: BC012089.1
Coding sequence: 236..2806
11 21 31 41 51
I I I I I
ATGCTCTCAG CTCTCCCGCC GCGGGATGGT GCCTTGAGTG AATGACCCCC TTGGAGAACA 60 TTCTTCCGCA TCCCTCGCCT CAAGCCAGCC TCAGACAGAA AACTGAAGAT TCAGCAGATC 120 CAGTGCTTCC TGCTCCTCTT CTGCCCAGGA ACACGCTTGC CTTCCCCAAG GCTTCCAGAA 180 GCTCTGAGGC AGGAGGCACC AAGTTCTACC TCATGTTTGG AGGATCTTGC TAGCTATGGC 240 CCTCGTACTC GGCTCCCTGT TGCTGCTGGG GCTGTGCGGG AACTCCTTTT CAGGAGGGCA 300 GCCTTCATCC ACAGATGCTC CTAAGGCTTG GAATTATGAA TTGCCTGCAA CAAATTATGA 360 GACCCAAGAC TCCCATAAAG CTGGACCCAT TGGCATTCTC TTTGAACTAG TGCATATCTT 420 TCTCTATGTG GTACAGCCGC GTGATTTCCC AGAAGATACT TTGAGAAAAT TCTTACAGAA 480 GGCATATGAA TCCAAAATTG ATTATGACAA GATTGTCTAC TATGAAGCAG GGATTATTCT 540 ATGCTGTGTC CTGGGGCTGC TGTTTATTAT TCTGATGCCT CTGGTGGGGT ATTTCTTTTG 600 TATGTGTCGT TGCTGTAACA AATGTGGTGG AGAAATGCAC CAGCGACAGA AGGAAAATGG 660 GCCCTTCCTG AGGAAATGCT TTGCAATCTC CCTGTTGGTG ATTTGTATAA TAATAAGCAT 720 TGGCATCTTC TATGGTTTTG TGGCAAATCA CCAGGTAAGA ACCCGGATCA AAAGGAGTCG 780 GAAACTGGCA GATAGCAATT TCAAGGACTT GCGAACTCTC TTGAATGAAA CTCCAGAGCA 840 AATCAAATAT ATATTGGCCC AGTACAACAC TACCAAGGAC AAGGCGTTCA CAGATCTGAA 900 CAGTATCAAT TCAGTGCTAG GAGGCGGAAT TCTTGACCGA CTGAGACCCA ACATCATCCC 960 TGTTCTTGAT GAGATTAAGT CCATGGCAAC AGCGATCAAG GAGACCAAAG AGGCGTTGGA 1020 GAACATGAAC AGCACCTTGA AGAGCTTGCA CCAACAAAGT ACACAGCTTA GCAGCAGTCT 1080 GACCAGCGTG AAAACTAGCC TGCGGTCATC TCTCAATGAC CCTCTGTGCT TGGTGCATCC 1140 ATCAAGTGAA ACCTGCAACA GCATCAGATT GTCTCTAAGC CAGCTGAATA GCAACCCTGA 1200 ACTGAGGCAG CTTCCACCCG TGGATGCAGA ACTTGACAAC GTTAATAACG TTCTTAGGAC 1260 AGATTTGGAT GGCCTGGTCC AACAGGGCTA TCAATCCCTT AATGATATAC CTGACAGAGT 1320 ACAACGCCAA ACCACGACTG TCGTAGCAGG TATCAAAAGG GTCTTGAATT CCATTGGTTC 1380 AGATATCGAC AATGTAACTC AGCGTCTTCC TATTCAGGAT ATACTCTCAG CATTCTCTGT 1440 TTATGTTAAT AACACTGAAA GTTACATCCA CAGAAATTTA CCTACATTGG AAGAGTATGA 1500 TTCATACTGG TGGCTGGGTG GCCTGGTCAT CTGCTCTCTG CTGACCCTCA TCGTGATTTT 1560 TTACTACCTG GGCTTACTGT GTGGCGTGTG CGGCTATGAC AGGCATGCCA CCCCGACCAC 1620 CCGAGGCTGT GTCTCCAACA CCGGAGGCGT CTTCCTCATG GTTGGAGTTG GATTAAGTTT 1680 CCTCTTTTGC TGGATATTGA TGATCATTGT GGTTCTTACC TTTGTCTTTG GTGCAAATGT 1740 GGAAAAACTG ATCTGTGAAC CTTACACGAG CAAGGAATTA TTCCGGGTTT TGGATACACC 1800 CTACTTACTA AATGAAGACT GGGAATACTA TCTCTCTGGG AAGCTATTTA ATAAATCAAA 1860 AATGAAGCTC ACTTTTGAAC AAGTTTACAG TGACTGCAAA AAAAATAGAG GCACTTACGG 1920 CACTCTTCAC CTGCAGAACA GCTTCAATAT CAGTGAACAT CTCAACATTA ATGAGCATAC 1980 TGGAAGCATA AGCAGTGAAT TGGAAAGTCT GAAGGTAAAT CTTAATATCT TTCTGTTGGG 2040 TGCAGCAGGA AGAAAAAACC TTCAGGATTT TGCTGCTTGT GGAATAGACA GAATGAATTA 2100 TGACAGCTAC TTGGCTCAGA CTGGTAAATC CCCCGCAGGA GTGAATCTTT TATCATTTGC 2160 ATATGATCTA GAAGCAAAAG CAAACAGTTT GCCCCCAGGA AATTTGAGGA ACTCCCTGAA 2220 AAGAGATGCA CAAACTATTA AAACAATTCA CCAGCAACGA GTCCTTCCTA TAGAACAATC 2280 ACTGAGCACT CTATACCAAA GCGTCAAGAT ACTTCAACGC ACAGGGAATG GATTGTTGGA 2340 GAGAGTAACT AGGATTCTAG CTTCTCTGGA TTTTGCTCAG AACTTCATCA CAAACAATAC 2400 TTCCTCTGTT ATTATTGAGG AAACTAAGAA GTATGGGAGA ACAATAATAG GATATTTTGA 2460 ACATTATCTG CAGTGGATCG AGTTCTCTAT CAGTGAGAAA GTGGCATCGT GCAAACCTGT 2520 GGCCACCGCT CTAGATACTG CTGTTGATGT CTTTCTGTGT AGCTACATTA TCGACCCCTT 2580 GAATTTGTTT TGGTTTGGCA TAGGAAAAGC TACTGTATTT TTACTTCCGG CTCTAATTTT 2640 TGCGGTAAAA CTGGCTAAGT ACTATCGTCG AATGGATTCG GAGGACGTGT ACGATGATGT 2700 TGAAACTATA CCCATGAAAA ATATGGAAAA TGGTAATAAT GGTTATCATA AAGATCATGT 2760 ATATGGTATT CACAATCCTG TTATGACAAG CCCATCACAA CATTGATAGC TGATGTTGAA 2820 ACTGCTTGAG CATCAGGATA CTCAAAGTGG AAAGGATCAC AGATTTTTGG TAGTTTCTGG 2880 GTCTACAAGG ACTTTCCAAA TCCAGGAGCA ACGCCAGTGG CAACGTAGTG ACTCAGGCGG 2940 GCACCAAGGC AACGGCACCA TTGGTCTCTG GGTAGTGCTT TAAGAATGAA CACAATCACG 3000 TTATAGTCCA TGGTCCATCA CTATTCAAGG ATGACTCCCT CCCTTCCTGT CTATTTTTGT 3060 TTTTTACTTT TTTACACTGA GTTTCTATTT AGACACTACA ACATATGGGG TGTTTGTTCC 3120 CATTGGATGC ATTTCTATCA AAACTCTATC AAATGTGATG GCTAGATTCT AACATATTGC 3180 CATGTGTGGA GTGTGCTGAA CACACACCAG TTTACAGGAA AGATGCATTT TGTGTACAGT 3240 AAACGGTGTA TATACCTTTT GTTACCACAG AGTTTTTTAA ACAAATGAGT ATTATAGGAC 3300 TTTCTTCTAA ATGAGCTAAA TAAGTCACCA TTGACTTCTT GGTGCTGTTG AAAATAATCC 3360 ATTTTCACTA AAAGTGTGTG AAACCTACAG CATATTCTTC ACGCAGAGAT TTTCATCTAT 3420 TATACTTTAT CAAAGATTGG CCATGTTCCA CTTGGAAATG GCATGCAAAA GCCATCATAG 3480 AGAAACCTGC GTAACTCCAT CTGACAAATT CAAAAGAGAG AGAGAGATCT TGAGAGAGAA 3540 ATGCTGTTCG TTCAAAAGTG GAGTTGTTTT AACAGATGCC AATTACGGTG TACAGTTTAA 3600 CAGAGTTTTC TGTTGCATTA GGATAAACAT TAATTGGAGT GCAGCTAACA TGAGTATCAT 3660 CAGACTAGTA TCAAGTGTTC TAAAATGAAA TATGAGAAGA TCCTGTCACA ATTCTTAGAT 3720 CTGGTGTCCA GCATGGATGA AACCTTTGAG TTTGGTCCCT AAATTTGCAT GAAAGCACAA 3780 GGTAAATATT CATTTGCTTC AGGAGTTTCA TGTTGGATCT GTCATTATCA AAAGTGATCA 3840 GCAATGAAGA ACTGGTCGGA CAAAATTTAA CGTTGATGTA ATGGAATTCC AGATGTAGGC 3900 ATTCCCCCCA GGTCTTTTCA TGTGCAGATT GCAGTTCTGA TTCATTTGAA TAAAAAGGAA 3960 CTTGGAAAAA AAAAAAAAAA AAA
Seq ID NO: 148 Protein sequence Protein Accession ft: AAH12089.1
11 21 31 41 51
I I I I I
MALVLGSLLL LGLCGNSFSG GQPSSTDAPK AWNYELPATN YETQDSHKAG PIGILFELVH 60 IFLYWQPRD FPEDTLRKFL QKAYESKIDY DKIVYYEAGI ILCCVLGLLF IILMPLVGYF 120 FCMCRCCNKC GGEMHQRQKE NGPFLRKCFA ISLLVICIII SIGIFYGFVA NHQVRTRIKR 180 SRKLADSNFK DLRTLLNETP EQIKYILAQY NTTKDKAFTD LNSINSVLGG GILDRLRPNI 240 IPVLDEIKSM ATAIKETKEA LENMNSTLKS LHQQSTQLSS SLTSVKTSLR SSLNDPLCLV 300 HPSSETCNSI RLSLSQLNSN PELRQLPPVD AELDNVNNVL RTDLDGLVQQ GYQSLNDIPD 360 RVQRQTTTW AGIKRVLNSI GSDIDNVTQR LPIQDILSAF SVYVNNTESY IHRNLPTLEE 420 YDSYWWLGGL VICSLLTLIV IFYYLGLLCG VCGYDRHATP TTRGCVSNTG GVFLMVGVGL 480 SFLFCWILMI IWLTFVFGA NVEKLICEPY TSKELFRVLD TPYLLNEDWE YYLSGKLFNK 540 SKMKLTFEQV YSDCKKNRGT YGTLHLQNSF NISEHLNINE HTGSISSELE SLKVNLNIFL 600 LGAAGRKNLQ DFAACGIDRM NYDSYLAQTG KSPAGVNLLS FAYDLEAKAN SLPPGNLRNS 660 LKRDAQTIKT IHQQRVLPIE QSLSTLYQSV KILQRTGNGL LERVTRILAS LDFAQNFITN 720 NTSSVIIEET KKYGRTIIGY FEHYLQWIEF SISEKVASCK PVATALDTAV DVFLCSYIID 780 PLNLFWFGIG KATVFLLPAL IFAVKLAKYY RRMDSEDVYD DVETIPMKNM ENGNNGYHKD 840 HVYGIHNPVM TSPSQH
Seq ID NO: 149 DNA sequence Nucleic Acid Accession #: NM_033049.1 Coding sequence: 28..1566
11 21 31 41 51
I I I I I
CCACGCGTCC GAGCAAGAAC AGCTAAAATG AAAGCCATCA TTCATCTTAC TCTTCTTGCT 60 CTCCTTTCTG TAAACACAGC CACCAACCAA GGCAACTCAG CTGATGCTGT AACAACCACA 120 GAAACTGCGA CTAGTGGTCC TACAGTAGCT GCAGCTGATA CCACTGAAAC TAATTTCCCT 180 GAAACTGCTA GCACCACAGC AAATACACCT TCTTTCCCAA CAGCTACTTC ACCTGCTCCC 240 CCCATAATTA GTACACATAG TTCCTCCACA ATTCCTACAC CTGCTCCCCC CATAATTAGT 300 ACACATAGTT CCTCCACAAT TCCTATACCT ACTGCTGCAG ACAGTGAGTC AACCACAAAT 360 GTAAATTCAT TAGCTACCTC TGACATAATC ACCGCTTCAT CTCCAAATGA TGGATTAATC 420 ACAATGGTTC CTTCTGAAAC ACAAAGTAAC AATGAAATGT CCCCCACCAC AGAAGACAAT 480 CAATCATCAG GGCCTCCCAC TGGCACCGCT TTATTGGAGA CCAGCACCCT AAACAGCACA 540 GGTCCCAGCA ATCCTTGCCA AGATGATCCC TGTGCAGATA ATTCGTTATG TGTTAAGCTG 600 CATAATACAA GTTTTTGCCT GTGTTTAGAA GGGTATTACT ACAACTCTTC TACATGTAAG 660 AAAGGAAAGG TATTCCCTGG GAAGATTTCA GTGACAGTAT CAGAAACATT TGACCCAGAA 720 GAGAAACATT CCATGGCCTA TCAAGACTTG CATAGTGAAA TTACTAGCTT GTTTAAAGAT 780 GTATTTGGCA CATCTGTTTA TGGACAGACT GTAATTCTTA CTGTAAGCAC ATCTCTGTCA 840 CCAAGATCTG AAATGCGTGC TGATGACAAG TTTGTTAATG TAACAATAGT AACAATTTTG 900 GCAGAAACCA CAAGTGACAA TGAGAAGACT GTGACTGAGA AAATTAATAA AGCAATTAGA 960 AGTAGCTCAA GCAACTTTCT AAACTATGAT TTGACCCTTC GGTGTGATTA TTATGGCTGT 1020 AACCAGACTG CGGATGACTG CCTCAATGGT TTAGCATGCG ATTGCAAATC TGACCTGCAA 1080 AGGCCTAACC CACAGAGCCC TTTCTGCGTT GCTTCCAGTC TCAAGTGTCC TGATGCCTGC 1140 AACGCACAGC ACAAGCAATG CTTAATAAAG AAGAGTGGTG GGGCCCCTGA GTGTGCGTGC 1200 GTGCCCGGCT ACCAGGAAGA TGCTAATGGG AACTGCCAAA AGTGTGCATT TGGCTACAGT 1260 GGACTCGACT GTAAGGACAA ATTTCAGCTG ATCCTCACTA TTGTGGGCAC CATCGCTGGC 1320 ATTGTCATTC TCAGCATGAT AATTGCATTG ATTGTCACAG CAAGATCAAA TAACAAAACG 1380 AAGCATATTG AAGAAGAGAA CTTGATTGAC GAAGACTTTC AAAATCTAAA ACTGCGGTCG 1440 ACAGGCTTCA CCAATCTTGG AGCAGAAGGG AGCGTCTTTC CTAAGGTCAG GATAACGGCC 1500 TCCAGAGACA GCCAGATGCA AAATCCCTAT TCAAGACACA GCAGCATGCC CCGCCCTGAC 1560 TATTAGAATC ATAAGAATGT GGAACCCGCC ATGGCCCCCA ACCAATGTAC AAGCTATTAT 1620 TTAGAGTGTT TAGAAAGACT GATGGAGAAG TGAGCACCAG TAAAGATCTG GCCTCCGGGG 1680 TTTTTCTTCC ATCTGACATC TGCCAGCCTC TCTGAATGGA AGTTGTGAAT GTTTGCAACG 1740 AATCCAGCTC ACTTGCTAAA TAAGAATCTA TGACATTAAA TGTAGTAGAT GCTATTAGCG 1800 CTTGTCAGAG AGGTGGTTTT CTTCAATCAG TACAAAGTAC TGAGACAATG GTTAGGGTTG 1860 TTTTCTTAAT TCTTTTCCTG GTAGGGCAAC AAGAACCATT TCCAATCTAG AGGAAAGCTC 1920 CCCAGCATTG CTTGCTCCTG GGCAAACATT GCTCTTGAGT TAAGTGACCT AATTCCCCTG 1980 GGAGACATAC GCATCAACTG TGGAGGTCCG AGGGGATGAG AAGGGATACC CACCACCTTT 2040 CAAGGGTCAC AAGCTCACTC TCTGACAAGT CAGAATAGGG ACACTGCTTC TATCCCTCCA 2100 ATGGAGAGAT TCTGGCAACC TTTGAACAGC CCAGAGCTTG CAACCTAGCC TCACCCAAGA 2160 AGACTGGAAA GAGACATATC TCTCAGCTTT TTCAGGAGGC GTGCCTGGGA ATCCAGGAAC 2220 TTTTTGATGC TAATTAGAAG GCCTGGACTA AAAATGTCCA CTATGGGGTG CACTCTACAG 2280 TTTTTGAAAT GCTAGGAGGC AGAAGGGGCA GAGAGTAAAA AACATGACCT GGTAGAAGGA 2340 AGAGAGGCAA AGGAAACTGG GTGGGGAGGA TCAATTAGAG AGGAGGCACC TGGGATCCAC 2400 CTTCTTCCTT AGGTCCCCTC CTCCATCAGC AAAGGAGCAC TTCTCTAATC ATGCCCTCCC 2460 GAAGACTGGC TGGGAGAAGG TTTAAAAACA AAAAATCCAG GAGTAAGAGC CTTAGGTCAG 2520 TTTGAAATTG GAGACAAACT GTCTGGCAAA GGGTGCGAGA GGGAGCTTGT GCTCAGGAGT 2580 CCAGCCGTCC AGCCTCGGGG TGTAGGTTTC TGAGGTGTGC CATTGGGGCC TCAGCCTTCT 2640 CTGGTGACAG AGGCTCAGCT GTGGCCACCA ACACACAACC ACACACACAC AACCACACAC 2700 ACAAATGGGG GCAACCACAT CCAGTACAAG CTTTTACAAA TGTTATTAGT GTCCTTTTTT 2760 ATTTCTAATG CCTTGTCCTC TTAAAAGTTA TTTTATTTGT TATTATTATT TGTTCTTGAC 2820 TGTTAATTGT GAATGGTAAT GCAATAAAGT GCCTTTGTTA GATGGTGAAA AAAAAAAAAA 2880 AAAAAAA
Seq ID NO: 150 Protein sequence Protein Accession #: NP 149038.1
11 21 31 41 51
I I I I I
MKAIIHLTLL ALLSVNTATN QGNSADAVTT TETATSGPTV AAADTTETNF PETASTTANT 60 PSFPTATSPA PPIISTHSSS TIPTPAPPII STHSSSTIPI PTAADSESTT NVNSLATSDI 120 ITASSPNDGL ITMVPSETQS NNEMSPTTED NQSSGPPTGT ALLETSTLNS TGPSNPCQDD 180 PCADNSLCVK LHNTSFCLCL EGYYYNSSTC KKGKVFPGKI SVTVSETFDP EEKHSMAYQD 240 LHSEITSLFK DVFGTSVYGQ TVILTVSTSL SPRSEMRADD KFVNVTIVTI LAETTSDNEK 300 TVTEKINKAI RSSSSNFLNY DLTLRCDYYG CNQTADDCLN GLACDCKSDL QRPNPQSPFC 360 VASSLKCPDA CNAQHKQCLI KKSGGAPECA CVPGYQEDAN GNCQKCAFGY SGLDCKDKFQ 420 LILTIVGTIA GIVILSMIIA LIVTARSNNK TKHIEEENLI DEDFQNLKLR STGFTNLGAE 480 GSVFPKVRIT ASRDSQMQNP YSRHSSMPRP DY
Seq ID NO: 151 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 87..914
CGCGAGC 60
Figure imgf001012_0001
CTGCAGG 120
CTGGTAGCTC GGAGGTGGAC TGGTGCGAGG ACAACTACAC CATCGTGCCT GCTATCGCCG 180
AGTTCTACAA CACGATCAGC AATGTCTTAT TTTTCATTTT ACCGCCCATC TGCATGTGCT 240
TGTTTCGTCA GTATGCAACA TGCTTCAACA GTGGCATCTA CTTAATCTGG ACTCTTTTGG 300
TTGTAGTGGG AATTGGATCC GTCTACTTCC ATGCAACCCT TAGTTTCTTG GGTCAGATGC 360
TTGATGAACT TGCAGTCCTT TGGGTTCTGA TGTGTGCTTT GGCCATGTGG TTCCCCAGAA 420
GGTATCTACC AAAGATCTTT CGGAATGACC GGGGTAGGTT CAAGGTGGTG GTCAGTGTCC 480
TGTCTGCGGT TACGACGTGC CTGGCATTTG TCAAGCCTGC CATCAACAAC ATCTCTCTGA 540
TGACCCTGGG AGTTCCTTGC ACTGCACTGC TCATCGCAGA GCTAAAGAGG TGTGACAACA 600
TGCGTGTGTT TAAGCTGGGC CTCTTCTCGG GCCTCTGGTG GACCCTGGCC CTGTTCTGCT 660
GGATCAGTGA CCGAGCTTTC TGCGAGCTGC TGTCATCCTT CAACTTCCCC TACCTGCACT 720
GCATGTGGCA CATCCTCATC TGCCTTGCTG CCTACCTGGG CTGTGTATGC TTTGCCTACT 780
TTGATGCTGC CTCAGAGATT CCTGAGCAAG GCCCTGTCAT CAAGTTCTGG CCCAATGAGA 840
AATGGGCCTT CATTGGTGTC CCCTATGTGT CCCTCCTGTG TGCCAACAAG AAATCATCAG 900
TCAAGATCAC GTGATGGCAA GATGGTGGCT GGCTTCTCTG CTTATCGCCC CTCATGCAGT 960
GGGCTTCCTT TGCTAGGAAG ACAGCCAAGG GAGTTCGAAT AGTTGGGGTG TGGGCTATCT 1020
TTTCAAAAAT CTATTTGCTG GGGCTCTTAA TTTCTTTAGT GTTCTTTGTA TGTAGGGATT 1080
TAAACTTTGT CATATGGTAC AAATATTCCC TGCCCCCCTG CAGTTTCCCA TTTGTCTTTC 1140
AGTATGTTAA TATTTTTGTG CCATACTGGT TTTAAACTTT CATGTTGTCA CATCTGTTAA 1200
TCTTTTCTTT AGGATTTCTG GATTTTGTGT AATTTTTAAA AAGGTCCCCT CCTCCTCCCT 1260
AATGTGTCTG TGGACCACCT GGATTCCACT GTACAAGGGG AAAAGTGTCT ATTCCTTTCC 1320
CAAAGATGGA AAATGGAGGG CTTAGGGACA CTAGATGCAT CTTTCTCAGC ATCACTTCCA 1380
GATGCAGTGA CTTGTTGGGC TGCGTCCTTA ATGGCCATGG CAGAGCAGTC CCTTGGGGGA 1440
TCCAGCCCTG TACAATGCAT CTCTTCCTGG AGAAAGCTGG CCTGCTCCAG ACCCCACCAT 1500
TCCCAGGCGC CCTTGGAGTG GACTCTACTG ATGACAGACA GACCCTCTGA GAGACAAGAC 1560
CCTCTGACTC TGTGATGGAA GATGCCAGAG ATTTTCCTTT GGGGTAATTG TCCTTAAACA 1620
AAACCAAACA GATGAAACAC ACACAGGACT TGTGGCTAAA AAGGCTAGTT TTTCACTTGC 1680
ATTTCTCAAC TAACCCAGGT TTTACATGCA TCTGTGAATC CTTTTACTAC TACCTCTGTG 1740
GAGAGATGGA GAGACTTCAG ATAAACGTGA AGCTAATGAG TAAAACCCTC TCTGCCAAAA 1800
CCTACACTCC ACTTTAGGCC CTTCTTGAAG ATGAGCACAA TTTTTAAATA CTGAGCACAA 1860
TTTTTAAATA CTGACATCAC TTCCTCTTCC CCCTCCCACC CCAGCTCAGC AGCCTCAAAT 1920
CTACAGAGAA GAAGAATTAT GGCATGAACA TTCCCACAGA CCCACCATCT TTAAGACTTG 1980
ACCTCTGTAA GTTTACCAAA GGGCTCCTCA CAATTGTGGT GGGGGTTCTG GTTCAAAATT 2040 TGGAGCAAAC ATGAAGTTTT TGGAAACGTT TTCTCATTTG AAGCCTCCAG TATGCTGTAC 2100 TATTCTGGAA ATTACCTTCA AGAGTCTCAC TTCTTGTTTC TGTTGTGTTT TCTGTGGGCA 2160 TCATGTTCTT CACGCTTGCA GTAGAAGGTG CTTTCTCGGT TTCCCAGAGT ATCCAACGGC 2220 TCACCTTTCT CAAGTGCTGG CAGTAGCTAT GCACTCACGG GCTGGTTTGG GTCGCTGGTG 2280 CAGCAGCGCA AATCTGTTGC CTTCTGAATT TTTCTCACCT AATGTGACAC TGGCTACAAT 2340 GAATCTTCTC TTCATCGGGC TGAATGAAAG ATTCAAGAAC CATCTTCAAG GTGCATGGTG 2400 GGAATTATCA ACCTCAGGGA TACTCATTTT AACTCAGGCG TGTCCTGCTT TGTAACATTC 2460 CATTGTTGGG AGAGGGCAGG ACAGGTGTGT TCTTCTGTGG GCAGGAGTCA TGTCACTGTC 2520 CTACATATGT AAGAGTTGGG AAGGTGACGA TTTTTGACAC ATCCAGGAAC TCTTACTCTA 2580 GTTAGAATTT GTACCAGATC CAAGGTGAAA ACCCCAATAA GCAACTGAAT TTAGAGTTTA 2640 AAAATGAATG ACTTTATGCT ACATCTGTGG TTATCAAATT ATATAGGTTG TTGAGAAGCA 2700 GAACGCTGTT TGTAGTAAGA AATCTTTCTβ GAACCCCAGT GTGTGAAGTA AATTGTATGT 2760 TATTAAATTT ATTTAAGGTT AAATTTATGG CATTTACTTA ATAATATATG AGGTGGTGAA 2820 AATGCAAATT AACAAATTGG TAATTTCCAA GGTAGAAAAA TTAGGTGTTG AATGAATGTA 2880 TATGTTGGTT TATTATAGTT TTATATATAT ATAGAGAGAG TGTTTTGTTT TTGAGTCAGG 2940 GTCTTGCTCT ATTACCCAGG CTGGAGTGCA GTGGTGCAGT CATGACTCAC TGTAGCCTCT 3000 GTCTCCCAGG CTCAAGTGAT CCTCTCACCT CAGCCTCCCC AGGAGCTGGG AGTACTGGTG 3060 CGTGCCTCCA CTCCCAGCTA ATTTTTGTAT TTTTTCATAG AGATGGGGTT TCACCATTTT 3120 GCCCAGGCTG GTCTCAAACT TCTGGGCTCA AGAGATTCGC CCGCCTCGGC CTCCCAAAGT 3180 GCTGGGAATA GGCATGAGCC GTCACGCCTG GCCTAAAAAA TATTTTTAAA ATGATCTTTG 3240 AATTAAATAT TCGTAGAATT TCTAATGTAT CTCTTTGAGA CCTAGGAGGT TGATGGAACA 3300 GAACTGCTGT TAAGTCCTTT GGGTTTCAAG TCTAGAATTT TTTAAAGGCA AATATCAGCT 3360 CATTCTTATT TTAGATTGAC CTTATCAGGC ATGGATTCTG GTCTCATCTA CTTTATGGTA 3420 TAAATGCTCC AAGGTAGGGβ GTTTGGTATA TATTTTAAGC CCGGCTTTTT 3480 TTTTTAATGT GAGAAGCAGA ATGTGCTTCT AGAAACTGGT TTTAAAGAGA 3540
TGAGCTGAGA AAGAAATGTG GAATGGAGTA TATTTGAGGA GGACAAAACA TAACTTCACT 3600 TTTGAACAGA AATCACTCTA GCTTGCCAGC ATGGGATGTA AACCAAGAGA GTAGAAATAT 3660 ACCCATCTTA TTTTAAGTTβ GGTTTATGGC ATCGCTCATA TATGTAAAAG CACTACAAAC 3720 TCTTTAAAGA AAATTGGGAA ACTACAGAGA AGTCAAAGAA AAAAAAAAGT AACCCATATT 3780 TCTATTGCCC AGGTATAATC CTTGTTAATA TTTTGGTTTG GTCTCCTCTT TTTTTCCCCC 3840 AATATAGTTG TAAATAAATG ATGTCTTTCA GAGTTGACAT TTATCCTGTA GCTTGAATGG 3900 CATGTAAATG CCAGTTGTAT ATTTTTTCAT GAAGTGTAGG TTTGGAATAC ACTAGAGTTA 3960 GCTATATGCT TGAATGCTGA TCACTGGATT CTGAGACTGA CTACTGAGTC TACCTTTTTA 4020 ATCAAGCCTA ACATGAATGG GCTCCAAAAA GTAATGAATG TAATTGTACT TTTTGATGTG 4080 CCTCTGCACT TGGCTTGGTG AGTCATCATA AATAGCTGTT AAATATGTGA CTTTACAGAT 4140 TTTGATATGT TCAGATTGTA AAAAATGAAT AGTTTATTTC ATTAATTGAT GGGCAGTCAA 4200 GAATCTCCCT CC
Seq ID NO: 152 Protein sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
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MGAPHWWDQL QAGSSEVDWC EDNYTIVPAI AEFYNTISNV LFFILPPICM CLFRQYATCF 60
NSGIYLIWTL LVWGIGSVY FHATLSFLGQ MLDELAVLWV LMCALAMWFP RRYLPKIFRN 120
DRGRFKVWS VLSAVTTCLA FVKPAINNIS LMTLGVPCTA LLIAELKRCD NMRVFKLGLF 180
SGLWWTLALF CWISDRAFCE LLSSFNFPYL HCMWHILICL AAYLGCVCFA YFDAASEIPE 240 QGPVIKFWPN EKWAFIGVPY VSLLCANKKS SVKIT
Seq ID NO: 153 DNA εequence
Nucleic Acid Acceεεion ft: NM_001432.1
Coding εequence: 167..676
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I I I I
TCACTTGCCT GATATTTCCA GTGTCAGAGG GACACAGCCA A 1CGTGGGGTC CCTTCTAGGC 60 TGACAGCCGC TCTCCAGCCA CTGCCGCGAG CCCGTCTGCT CCCGCCCTGC CCGTGCACTC 120 TCCGCAGCCG CCCTCCGCCA AGCCCCAGCG CCCGCTCCCA TCGCCGATGA CCGCGGGGAG 180 GAGGATGGAG ATGCTCTGTG CCGGCAGGGT CCCTGCGCTG CTGCTCTGCC TGGGTTTCCA 240 TCTTCTACAG GCAGTCCTCA GTACAACTGT GATTCCATCA TGTATCCCAG GAGAGTCCAG 300
TGATAACTGC ACAGCTTTAG TTCAGACAGA AGACAATCCA CGTGTGGCTC AAGTGTCAAT 360 AACAAAGTGT AGCTCTGACA TGAATGGCTA TTGTTTGCAT GGACAGTGCA TCTATCTGGT 420 GGACATGAGT CAAAACTACT GCAGGTGTGA AGTGGGTTAT ACTGGTGTCC GATGTGAACA 480 CTTCTTTTTA ACCGTCCACC AACCTTTAAG CAAAGAGTAT GTGGCTTTGA CCGTGATTCT 540 TATTATTTTG TTTCTTATCA CAGTCGTCGG TTCCACATAT TATTTCTGCA GATGGTACAG 600 AAATCGAAAA AGTAAAGAAC CAAAGAAGGA ATATGAGAGA GTTACCTCAG GGGATCCAGA 660 GTTGCCGCAA GTCTGAATGG CGCCATCAAA CTTATGGGCA GGGATAACAG TGTGCCTGGT 720 TAATATTAAT ATTCCATTTT ATTAATAATA TTTATGTTGG GTCAAGTGTT AGGTCAATAA 780 CACTGTATTT TAATGTACTT GAAAAATGTT TTTATTTTTG TTTTATTTTT GACAGACTAT 840 TTGCTAATGT ATAATGTGCA GAAAATATTT AATATCAAAA GAAAATTGAT ATTTTTATAC 900 AAGTAATTTC CTGAGCTAAA TGCTTCATTG AAAGCTTCAA AGTTTATATG CCTGGTGCAC 960 AGTGCTTAGA AGTAAGCAAT TCCCAGGTCA TAGCTCAAGA ATTGTTAGCA AATGACAGAT 1020 TTCTGTAAGC CTATATATAT AGTCAAATCG ATTTAGTAAG TATGTTTTTT ATGTTCCTCA 1080 AATCAGTGAT AATTGGTTTG ACTGTACCAT GGTTTGATAT GTAGTTGGCA CCATGGTATC 1140 ATATATTAAA ACAATAATGC AATTAGAATT TGGGAGAAGC AAATATAGGT CCTGTGTTAA 1200 ACACTACACA TTTGAAACAA GCTAACCCTG GGGAGTCTAT GGTCTCTTCA CTCAGGTCTC 1260 AGCTATAATT CTGTTATATG AGGGGCAGTG GACAGTTCCC TATGCCAACT CACGACTCCT 1320 ACAGGTACTA GTCACTCATC TACCAGATTC TGCCTATGTA AAATGAATTG AAAAACAATT 1380 TTCTGTAATC TTTTATTTAA GTAGTGGGCA TTTCATAGCT TCACAATGTT CCTTTTTTGT 1440 ATATTACAAC ATTTATGTGA GGTAATTATT GCTCAACAGA CAATTAGAAA AAAGTCCACA 1500 CTTGAAGCCT AAATTTGTGC TTTTTAAGAA TATTTTTAGA CTATTTCTTT TTATAGGGGC 1560 TTTGCTGAAT TCTAACATTA AATCACAGCC CAAAATTTGA TGGACTAATT ATTATTTTAA 1620 AATATATGAA GACAATAATT CTACATGTTG TCTTAAGATG GAAATACAGT TATTTCATCT 1680 TTTATTCAAG GAAGTTTTAA CTTTAATACA GCTCAGTAAA TGGCTTCTTC TAGAATGTAA 1740 AGTTATGTAT TTAAAGTTGT ATCTTGACAC AGGAAATGGG AAAAAACTTA AAAATTAATA 1800 TGGTGTATTT TTCCAAATGA AAAATCTCAA TTGAAAGCTT TTAAAATGTA GAAACTTAAA 1860 CACACCTTCC TGTGGAGGCT GAGATGAAAA CTAGGGCTCA TTTTCCTGAC ATTTGTTTAT 1920 TTTTTGGAAG AGACAAAGAT TTCTTCTGCA CTCTGAGCCC ATAGGTCTCA GAGAGTTAAT 1980 AGGAGTATTT TTGGGCTATT GCATAAGGAG CCACTGCTGC CACCACTTTT GGATTTTATG 2040 GGAGGCTCCT TCATCGAATG CTAAACCTTT GAGTAGAGTC TCCCTGGATC ACATACCAGG 2100 TCAGGGAGGA TCTGTTCTTC CTCTACGTTT ATCCTGGCAT GTGCTAGGGT AAACGAAGGC 2160 ATAATAAGCC ATGGCTGACC TCTGGAGCAC CAGGTGCCAG GACTTGTCTC CATGTGTATC 2220 CATGCATTAT ATACCCTGGT GCAATCACAC GACTGTCATC TAAAGTCCTG GCCCTGGCCC 2280 0 TTACTATTAG GAAAATAAAC AGACAAAAAC AAGTAAATAT ATATGGTCCT ATACATATTG 2340 TATATATATT CATATACAAA CATGTATGTA TACATGACCT TAATGGATCA TAGAATTGCA 2400 GTCATTTGGT GCTCTGCTAA CCATTTATAT AAAACTTAAA AAGAAGAGAA AAGAAAAATC 2460 AATTAGATCT AAACAGTTAT TTCTGTTTCC TATTTAATAT AGCTGAAGTC AAAATATGTA 2520 AGAACACATT TTAAATACTC TACTTACAGT TGGCCCTCTG TGGTTAGTTC CACATCTGTG 2580 5 GATTCAACCA ACCAAGGACG GAAAATGCTT AAAAAATAAT ACAACAACAA CAAAAAATAC 2640 ATTATAACAA CTATTTACTT τχχ-_χτχχτT CTTTTTGAGA TGGAGTCTCG CTCTGTTGCC 2700 CAGGTTGGAG TGCAGTGGCA CGATCTCGGC TCACTGCAAC CTCACCTCCC GGGTTCAAGA 2760 GATCCTCCTG CCTCAGCCTC CTGAGCAGCT GGGACTACAG GCGCATGCCA CCATGCCCAG 2820 CTAATTTTTG TATTTTTAGT AGAGGCGGGG TTTCACCATG TTGGCCAGGA TGGTCTCAAT 2880 0 CTCCTAACCT TGAGATCCAC CCTCCACAGC CTCCCAAACT GCTGGGATTA CAGGCGTGAG 2940 CCACCGCACG TAGCATTTAC ATTAGGTATT ACAAGTAATG TAAAGATGAT TTAAGTATAC 3000 AGGAGGATGT GAATAGGTTA TATGCAAGCA CTATGCCCTT TTATATAAGT GACTTGAACA 3060 TCTGTGCCCG ATTTTAGTAT GTGCAGGGGG GCGATCTGGG AATCAGTCCC CTGTGGATAC 3120 CAAGGTACAA CTGTATTTAT TAACGCTTAC TAGATGTGAG GAGAGTCTGA ATATTTTCAG 3180 5 TGATCTTGGC TGTTTCAAAA AAATCTATTG ACTTTTCAAT AAATCAGCTG CAATCCATTT 3240 ATTTCATTTA CAAAAGATTT ATTGTAAGCC TCTCAATCTT GGTTTTTCAG TTGATCTTAA 3300 GCATGTCAAT TCATAAAAAC AAGTCATTTT TGTATTTTTC ATCTTTAAGA ATGCTTAAAA 3360 AAGCTAATCC CTAAAATAGT TAGATCTTTG TAAATGCATA TTAAATAATA AAGTATGACC 3420 CACATTACTT TTTATGGGTG AAAATAAGAC AAAAATAATA GTTTTAGTGA GGATGGTGCT 3480 0 GAGTAAACAT AAAAACTGAT TTGCTCTCAG CTGATGTGTC CTGTACACAG TGGGAAGATT 3540 TTAGTTCACA CTTAGTCTAA CTCCCCCATT TTACAGATTT CTCACTATAT ATATTTCTAG 3600 AAGGGGCTAT GCATATTCAA TGTATTGAGA ACCAAAGCAA CCACAAATGC ATAAATGCAT 3660 AATTTATGGT CTTCAACCAA GGCCACATAA TAACCCAGTT AACTTACTCT TTAACCAGGA 3720 ATATTAAGTT CTATAACTAG TACTCAAGGT TTAACCTTAA AATTAAGATT TCCTTAACCT 3780 5 TAACCTTAAA ATTGATATTA TATTAAACAT ACATAATACA ATGTAACTCC ACTGTTCTCC 3840 TGAATATTTT TTGCTCTAAT CTCTCTGCCG AAAGTCAAAG TGATGGGAGA ATTGGTATAC 3900 TGGTATGACT ACGTCTTAAG TCAGATTTTT ATTTATGAGT CTTTGAGACT AAATTCAATC 3960 ACCACCAGGT ATCAAATCAA CTTTTATGCA GCAAATATAT GATTCTAGTG TCTGACTTTT 4020 GTTAAATTCA GTAATGCAGT TTTTAAAAAC CTGTATCTGA CCCACTTTGT AATTTTTGCT 4080 0 CCAATATCCA TTCTGTAGAC TTTTGAAAAA AAAGTTTTTA ATTTGATGCC CAATATATTC 4140 TGACCGTTAA AAAATTCTTG TTCATATGGG AGAAGGGGGA GTAATGACTT GTACAAACAG 4200 TATTTCTGGT GTATATTTTA ATGTTTTTAA AAAGAGTAAT TTCATTTAAA , TATCTGTTAT 4260 TCAAATTTGA TGATGTTAAA TGTAATATAA TGTATTTTCT TTTTATTTTG : CACTCTGTAA 4320 TTGCACTTTT TAAGTTTGAA GAGCCATTTT GGTAAACGGT TTTTATTAAA . GATGCTATGG 4380 5 AACATAAAGT TGTATTGCAT GCAATTTAAA GTAACTTATT TGACTATGAA . TATTATCGGA 4440 TTACTGAATT GTATCAATTT GTTTGTGTTC AATATCAGCT TTGATAATTG 1 TGTACCTTAA 4500 GATATTGAAG GAGAAAATAG ATAATTTACA AGATATTATT AATTTTTATT 1 TATTTTTCTT 4560 GGGAATTGAA AAAAATTGAA ATAAATAAAA ATGCATTGAA CATCTTGCAT ' TCAAAATCTT 4620 CACTGAC 0
Seq ID NO : 154 Protein sequence Protein Accession ft : NP 001423 .1
_ _ 1 11 21 31 41 51 5 I i i i i I
MTAGRRMEML CAGRVPALLL CLGFHLLQAV LSTTVIPSCI PGESSDNCTA LVQTEDNPRV 60 AQVSITKCSS DMNGYCLHGQ CIYLVDMSQN YCRCEVGYTG VRCEHFFLTV HQPLSKEYVA 120 LTVILIILFL ITWGSTYYF CRWYRNRKSK EPKKEYERVT SGDPELPQV
60 Seq ID NO : 155 DNA sequence
Nucleic Acid Accession # : NM_013282 .2 Coding sequence : 85 . . 2466
1 11 21 31 41 51
65 1 1 | 1 1 | 1 | 1 | 1 CGACTCCTTA GAGCATGGCA TGGCTCAGAG GTGCTGGTAA AACTGATGGG GGTTTTTGCT 60
GTCCCTCCCC TCAGCGCCGA CACCATGTGG ATCCAGGTTC GGACCATGGA CGGGAGGCAG 120
ACCCACACGG TGGACTCGCT GTCCAGGCTG ACCAAGGTGG AGGAGCTGAG GCGGAAGATC 180
CAGGAGCTGT TCCACGTGGA GCCAGGCCTG CAGAGGCTGT TCTACAGGGG CAAACAGATG 240
70 GAGGACGGCC ATACCCTCTT CGACTACGAG GTCCGCCTGA ATGACACCAT CCAGCTCCTG 300
GTCCGCCAGA GCCTCGTGCT CCCCCACAGC ACCAAGGAGC GGGACTCCGA GCTCTCCGAC 360
ACCGACTCCG GCTGCTGCCT GGGCCAGAGT GAGTCAGACA AGTCCTCCAC CCACGGCGAG 420
GCGGCCGCCG AGACTGACAG CAGGCCAGCC GATGAGGACA TGTGGGATGA GACGGAATTG 480
GGGCTGTACA AGGTCAATGA GTACGTCGAT GCTCGGGACA CGAACATGGG GGCGTGGTTT 540
75 GAGGCGCAGG TGGTCAGGGT GACGCGGAAG GCCCCCTCCC GGGACGAGCC CTGCAGCTCC 600
ACGTCCAGGC CGGCGCTGGA GGAGGACGTC ATTTACCACG TGAAATACGA CGACTACCCG 660
GAGAACGGCG TGCTCCAGAT GAACTCCAGG GACGTCCGAG CGCGCGCCCG CAGCATCATC 720
AAGTGGCAGG ACCTGGAGGT GGGCCAGGTG GTCATGCTCA ACTACAACCC CGACAACCCC 780
AAGGAGCGGG GCTTCTGGTA CGACGCGGAG ATCTCCAGGA AGCGCGAGAC CAGGACGGCG 840
80 CGGGAACTCT ACGCCAACGT GGTGCTGGGG GATGATTCTC TGAACGACTG TCGGATCATC 900
TTCGTGGACG AAGTCTTCAA GATTGAGCGG CCGGGTGAAG GGAGCCCCAT GGTTGACAAC 960
CCCATGAGAC GGAAGAGCGG GCCGTCCTGC AAGCACTGCA AGGACGACGT GAACAGACTC 1020
TGCCGGGTCT GCGCCTGCCA CCTGTGCGGG GGCCGGCAGG ACCCCGACAA GCAGCTCATG 1080
TGCGATGAGT GCGACATGGC CTTCCACATC TACTGCCTGG ACCCGCCCCT CAGCAGTGTT 1140 CCCAGCGAGG ACGAGTGGTA CTGCCCTGAG TGCCGGAATG ATGCCAGCGA GGTGGTACTG 1200
GCGGGAGAGC GGCTGAGAGA GAGCAAGAAG AAGGCGAAGA TGGCCTCGGC CACATCGTCC 1260
TCACAGCGGG ACTGGGGCAA GGGCATGGCC TGTGTGGGCC GCACCAAGGA ATGTACCATC 1320
GTCCCGTCCA ACCACTACGG ACCCATCCCG GGGATCCCCG TGGGCACCAT GTGGCGGTTC 1380
CGAGTCCAGG TCAGCGAGTC GGGTGTCCAT CGGCCCCACG TGGCTGGCAT ACACGGCCGG 1440
AGCAACGACG GAGCGTACTC CCTAGTCCTG GCGGGGGGCT ATGAGGATGA CGTGGACCAT 1500
GGGAATTTTT TCACATACAC GGGTAGTGGT GGTCGAGATC TTTCCGGCAA CAAGAGGACC 1560
GCGGAACAGT CTTGTGATCA GAAACTCACC AACACCAACA GGGCGCTGGC TCTCAACTGC 1620
TTTGCTCCCA TCAATGACCA AGAAGGGGCC GAGGCCAAGG ACTGGCGGTC GGGGAAGCCG 1680
GTCAGGGTGG TGCGCAATGT CAAGGGTGGC AAGAATAGCA AGTACGCCCC CGCTGAGGGC 1740
AACCGCTACG ATGGCATCTA CAAGGTTGTG AAATACTGGC CCGAGAAGGG GAAGTCCGGG 1800
TTTCTCGTGT GGCGCTACCT TCTGCGGAGG GACGATGATG AGCCTGGCCC TTGGACGAAG 1860
GAGGGGAAGG ACCGGATCAA GAAGCTGGGG CTGACCATGC AGTATCCAGA AGGCTACCTG 1920
GAAGCCCTGG CCAACCGAGA GCGAGAGAAG GAGAACAGCA AGAGGGAGGA GGAGGAGCAG 1980
CAGGAGGGGG GCTTCGCGTC CCCCAGGACG GGCAAGGGCA AGTGGAAGCG GAAGTCGGCA 2040
GGAGGTGGCC CGAGCAGGGC CGGGTCCCCG CGCCGGACAT CCAAGAAAAC CAAGGTGGAG 2100
CCCTACAGTC TCACGGCCCA GCAGAGCAGC CTCATCAGAG AGGACAAGAG CAACGCCAAG 2160
CTGTGGAATG AGGTCCTGGC GTCACTCAAG GACCGGCCGG CGAGCGGCAG CCCGTTCCAG 2220
TTGTTCCTGA GTAAAGTGGA GGAGACGTTC CAGTGTATCT GCTGTCAGGA GCTGGTGTTC 2280
CGGCCCATCA CGACCGTGTG CCAGCACAAC GTGTGCAAGG ACTGCCTGGA CAGATCCTTT 2340
CGGGCACAGG TGTTCAGCTG CCCTGCCTGC CGCTACGACC TGGGCCGCAG CTATGCCATG 2400
GAGGTGAACC AGCCTCTGCA GACCGTCCTC AACCAGCTCT TCCCCGGCTA CGGCAATGGC 2460
CGGTGATCTC CAAGCACTTC TCGACAGGCG TTTTGCTGAA AACGTGTCGG AGGGCTCGTT 2520
CATCGGCACT GATTTTGTTC TTAGTGGGCT TAACTTAAAC AGGTAGTGTT TCCTCCGTTC 2580
CCTAAAAAGG TTTGTCTTCC TTTTTTTTTA TTTTTATTTT TCAAATCTAT ACATTTTCAG 2640
GAATTTATGT ATTCTGGCTA AAAGTTGGAC TTCTCAGTAT TGTGTTTAGT TCTTTGAAAA 2700
CATAAAAGCC TGCAATTTCT CGACAAAACA ACACAAGATT TTTTAAAGAT GGAATCAGAA 2760
ACTACGTGGT GTGGAGGCTG TTGATGTTTC TGGTGTCAAG TTCTCAGAAG TTGCTGCCAC 2820
CAACTCTTTA AGAAGGCGAC AGGATCAGTC CTTCTCTAGG GTTCTGGCCC CCAAGGTCAG 2880
AGCAAGCATC TTCCTGACAG CATTTTGTCA TCTAAAGTCC AGTGACATGG TTCCCCGTGG 2940
TGGCCCGTGG CAGCCCGTGG CATGGCGTGG CTCAGCTGTC TGTTGAAGTT GTTGCAAGGA 3000
AAAGAGGAAA CATCTCGGGC CTAGTTCAAA CCTTTGCCTC AAAGCCATCC CCCACCAGAC 3060
TGCTTAGCGT CTGAGATCCG CGTGAAAAGT CCTCTGCCCA CGAGAGCAGG GAGTTGGGGC 3120
CACGCAGAAA TGGCCTCAAG GGGACTCTGC TCCACGTGGG GCCAGGCGTG TGACTGACGC 3180
TGTCCGACGA AGGCGGCCAC GGACGGACGC CAGCACACGA AGTCACGTGC AAGTGCCTTT 3240
GATTCGTTCC TTCTTTCTAA AGACGACAGT CTTTGTTGTT AGCACTGAAT TATTGAAAAT 3300
GTCAACCAGA TTCTAGAAAC TGCGGTCATC CAGTTCTTCC TGACACCGGA TGGGTGCTTG 3360
GGAACCGTTT GAGCCTTATA GATCATTTAC ATTCAATTTT TTTAACTCAG CAAGTGAGAA 3420
CTTACAAGAG GGTTTTTTTT TAATTTTTTT TTCTCTTAAT GAACACATTT TCTAAATGAA 3480
TTTTTTTTGT AGTTACTGTA TATGTACCAA GAAAGATATA ACGTTAGGGT TTGGTTGTTT 3540
TTGTTTTTGT ATTTTTTTTC TTTTGAAAGG GTTTGTTAAT TTTTCTAATT TTACCAAAGT 3600
TTGCAGCCTA TACCTCAATA AAACAGGGAT ATTTTAAATC ACATACCTGC AGACAAACTG 3660
GAGCAATGTT ATTTTTAAAG GGTTTTTTTC ACCTCCTTAT TCTTAGATTA TTAATGTATT 3720
AGGGAAGAAT GAGACAATTT TGTGTAGGCT TTTTCTAAAG TCCAGTACTT TGTCCAGATT 3780
TTAGATTCTC AGAATAAATG TTTTTCACAG ATTGAAAAAA AAAAAAAA
Seq ID NO: 156 Protein sequence Protein Accession #: NP 037414.2
11 21 31 41 51
I I I I I
MWIQVRTMDG RQTHTVDSLS RLTKVEELRR KIQELFHVEP GLQRLFYRGK QMEDGHTLFD 60 YEVRLNDTIQ LLVRQSLVLP HSTKERDSEL SDTDSGCCLG QSESDKSSTH GEAAAETDSR 120 PADEDMWDET ELGLYKVNEY VDARDTNMGA WFEAQWRVT RKAPSRDEPC SSTSRPALEE 180 DVIYHVKYDD YPENGWQMN SRDVRARART IIKWQDLEVG QWMLNYNPD NPKERGFWYD 240 AEISRKRETR TARELYANW LGDDSLNDCR IIFVDEVFKI ERPGEGSPMV DNPMRRKSGP 300 SCKHCKDDVN RLCRVCACHL CGGRQDPDKQ LMCDECDMAF HIYCLDPPLS SVPSEDEWYC 360 PECRNDASEV VLAGERLRES KKKAKMASAT SSSQRDWGKG MACVGRTKEC TIVPSNHYGP 420 IPGIPVGTMW RFRVQVSESG VHRPHVAGIH GRSNDGAYSL VLAGGYEDDV DHGNFFTYTG 480 SGGRDLSGNK RTAEQSCDQK LTNTNRALAL NCFAPINDQE GAEAKDWRSG KPVRWRNVK 540 GGKNSKYAPA EGNRYDGIYK WKYWPEKGK SGFLVWRYLL RRDDDEPGPW TKEGKDRIKK 600 LGLTMQYPEG YLEALANRER EKENSKREEE EQQEGGFASP RTGKGKWKRK SAGGGPSRAG 660 SPRRTSKKTK VEPYSLTAQQ SSLIREDKSN AKLWNEVLAS LKDRPASGSP FQLFLSKVEE 720 TFQCICCQEL VFRPITTVCQ HNVCKDCLDR SFRAQVFSCP ACRYDLGRSY AMQVNQPLQT
Seq ID NO: 157 DNA sequence
Nucleic Acid Accession #: NM_000756.
Coding sequence: 186..776
11 21 31 41 51
I I I I I
AGAAACTCAG AGACCAAGTC CATTGAGAGA CTGAGGGGAA AGAGAGGAGA GAAAGAAAAA 60 GAGAGTGGGA ACAGTAAAGA GAAAGGAAGA CAACCTCCAG AGAAAGCCCC CGGAGACGTC 120 TCTCTGCAGA GAGGCGGCAG CACCCGGCTC ACCTGCGAAG CGCCTGGGAA GCGAGTGCCC 180 CTAACATGCG GCTGCCGCTG CTTGTGTCCG CGGGAGTCCT GCTGGTGGCT CTCCTGCCCT 240 GCCCGCCATG CAGGGCGCTC CTGAGCCGCG GGCCGGTCCC GGGAGCTCGG CAGGCGCCGC 300 AGCACCCTCA GCCCTTGGAT TTCTTCCAGC CGCCGCCGCA GTCCGAGCAG CCCCAGCAGC 360 CGCAGGCTCG GCCGGTCCTG CTCCGCATGG GAGAGGAGTA CTTCCTCCGC CTGGGGAACC 420 TCAACAAGAG CCCGGCCGCT CCCCTTTCGC CCGCCTCCTC GCTCCTCGCC GGAGGCAGCG 480 GCAGCCGCCC TTCGCCGGAA CAGGCGACCG CCAACTTTTT CCGCGTGTTG CTGCAGCAGC 540 TGCTGCTGCC TCGGCGCTCG CTCGACAGCC CCGCGGCTCT CGCGGAGCGC GGCGCTAGGA 600 ATGCCCTCGG CGGCCACCAG GAGGCACCGG AGAGAGAAAG GCGGTCCGAG GAGCCTCCCA 660 TCTCCCTGGA TCTCACCTTC CACCTCCTCC GGGAAGTCTT GGAAATGGCC AGGGCCGAGC 720 AGTTAGCACA GCAAGCTCAC AGCAACAGGA AACTCATGGA GATTATTGGG AAATAAAACG 780 GTGCGTTTGG CCAAAAAGAA TCTGCATTTA GCACAAAAAA AATTTAAAAA AATACAGTAT 840
TCTGTACCAT AGCGCTGCTC TTATGCCATT TGTTTATTTT TATATAGCTT GAAACATAGA 900
GGGAGAGAGG GAGAGAGCCT ATACCCCTTA CTTAGCATGC ACAAAGTGTA TTCACGTGCA 960
GCAGCAACAC AATGTTATTC GTTTTGTCTA CGTTTAGTTT CCGTTTCCAG GTGTTTATAG 1020
TGGTGTTTTA AAGAGAATGT AGACCTGTGA GAAAACGTTT TGTTTGAAAA AGCAGACAGA 1080
AGTCACTCAA TTGTTTTTGT TGTGGTCTGA GCCAAAGAGA ATGCCATTCT CTTGGGTGGG 1140
TAAGACTAAA TCTGTAAGCT CTTTGAAACA ACTTTCTCTT GTAAACGTTT CAGTAATAAA 1200
ACATCTTTCC AGTCCTTGGT CAGTTTGGTT GTGTAAGAGA ATGTTGAATA CTTATATTTT 1260 TAATAAAAGT TGCAAAGGT
10
Seq ID NO: 158 Protein sequence Protein Accession #: NP 000747.1
, _ 1 11 21 31 41 51
15 I I I I I I
MRLPLLVSAG VLLVALLPCP PCRALLSRGP VPGARQAPQH PQPLDFFQPP PQSEQPQQPQ 60
ARPVLLRMGE EYFLRLGNLN KSPAAPLSPA SSLLAGGSGS RPSPEQATAN FFRVLLQQLL 120
LPRRSLDSPA ALAERGARNA LGGHQEAPER ERRSEEPPIS LDLTFHLLRE VLEMARAEQL 180 AQQAHSNRKL MEIIGK 0
Seq ID NO: 159 DNA sequence
Nucleic Acid Accession ft: NM_001200.1
Coding sequence: 325..1514
25 1 11 21 31 41 51
I I I I I I
GGGGACTTCT TGAACTTGCA GGGAGAATAA CTTGCGCACC CCACTTTGCG CCGGTGCCTT 60
TGCCCCAGCG GAGCCTGCTT CGCCATCTCC GAGCCCCACC GCCCCTCCAC TCCTCGGCCT 120
TGCCCGACAC TGAGACGCTG TTCCCAGCGT GAAAAGAGAG ACTGCGCGGC CGGCACCCGG 180
30 GAGAAGGAGG AGGCAAAGAA AAGGAACGGA CATTCGGTCC TTGCGCCAGG TCCTTTGACC 240
AGAGTTTTTC CATGTGGACG CTCTTTCAAT GGACGTGTCC CCGCGTGCTT CTTAGACGGA 300
CTGCGGTCTC CTAAAGGTCG ACCATGGTGG CCGGGACCCG CTGTCTTCTA GCGTTGCTGC 360
TTCCCCAGGT CCTCCTGGGC GGCGCGGCTG GCCTCGTTCC GGAGCTGGGC CGCAGGAAGT 420
TCGCGGCGGC GTCGTCGGGC CGCCCCTCAT CCCAGCCCTC TGACGAGGTC CTGAGCGAGT 480
35 TCGAGTTGCG GCTGCTCAGC ATGTTCGGCC TGAAACAGAG ACCCACCCCC AGCAGGGACG 540
CCGTGGTGCC CCCCTACATG CTAGACCTGT ATCGCAGGCA CTCAGGTCAG CCGGGCTCAC 600
CCGCCCCAGA CCACCGGTTG GAGAGGGCAG CCAGCCGAGC CAACACTGTG CGCAGCTTCC 660
ACCATGAAGA ATCTTTGGAA GAACTACCAG AAACGAGTGG GAAAACAACC CGGAGATTCT 720
TCTTTAATTT AAGTTCTATC CCCACGGAGG AGTTTATCAC CTCAGCAGAG CTTCAGGTTT 780
40 TCCGAGAACA GATGCAAGAT GCTTTAGGAA ACAATAGCAG TTTCCATCAC CGAATTAATA 840
TTTATGAAAT CATAAAACCT GCAACAGCCA ACTCGAAATT CCCCGTGACC AGACTTTTGG 900
ACACCAGGTT GGTGAATCAG AATGCAAGCA GGTGGGAAAG TTTTGATGTC ACCCCCGCTG 960
TGATGCGGTG GACTGCACAG GGACACGCCA ACCATGGATT CGTGGTGGAA GTGGCCCACT 1020
TGGAGGAGAA ACAAGGTGTC TCCAAGAGAC ATGTTAGGAT AAGCAGGTCT TTGCACCAAG 1080
45 ATGAACACAG CTGGTCACAG ATAAGGCCAT TGCTAGTAAC TTTTGGCCAT GATGGAAAAG 1140
GGCATCCTCT CCACAAAAGA GAAAAACGTC AAGCCAAACA CAAACAGCGG AAACGCCTTA 1200
AGTCCAGCTG TAAGAGACAC CCTTTGTACG TGGACTTCAG TGACGTGGGG TGGAATGACT 1260
GGATTGTGGC TCCCCCGGGG TATCACGCCT TTTACTGCCA CGGAGAATGC CCTTTTCCTC 1320
TGGCTGATCA TCTGAACTCC ACTAATCATG CCATTGTTCA GACGTTGGTC AACTCTGTTA 1380
50 ACTCTAAGAT TCCTAAGGCA TGCTGTGTCC CGACAGAACT CAGTGCTATC TCGATGCTGT 1440
ACCTTGACGA GAATGAAAAG GTTGTATTAA AGAACTATCA GGACATGGTT GTGGAGGGTT 1500 GTGGGTGTCG CTAGTACAGC AAAATTAAAT ACATAAATAT ATATATA
Seq ID NO: 160 Protein sequence
55 Protein Accession #: NP_001191.1
1 11 21 31 41 51
I I I I I I
MVAGTRCLLA LLLPQVLLGG AAGLVPELGR RKFAAASSGR PSSQPSDEVL SEFELRLLSM 60
60 FGLKQRPTPS RDAWPPYML DLYRRHSGQP GSPAPDHRLE RAASRANTVR SFHHEESLEE 120
LPETSGKTTR RFFFNLSSIP TEEFITSAEL QVFREQMQDA LGNNSSFHHR INIYEIIKPA 180 TANSKFPVTR LLDT
-_ Seq ID NO: 161 DNA sequence 65 Nucleic Acid Accession ff: NM_001999.2 Coding sequence: 1..8736
1 11 21 31 41 51
™ tU A ITGGGGAGAA G IACGGAGGCT G ITGTCTCCAG C ITCTACTTCC T IGTGGCTGGG C ITGTGTGGTG 60
CTCTGGGCGC AGGGCACGGC CGGCCAGCCT CAGCCTCCTC CGCCCAAGCC GCCCCGGCCC 120
CAGCCGCCGC CGCAACAGGT TCGGTCCGCT ACAGCAGGCT CTGAAGGCGG GTTTCTAGCG 180
CCCGAGTATC GCGAGGAGGG TGCCGCAGTG GCCAGCCGCG TCCGCCGGCG AGGACAGCAG 240
GACGTGCTCC GAGGGCCCAA CGTGTGCGGC TCCAGATTCC ACTCCTACTG CTGCCCTGGA 300
75 TGGAAGACGC TCCCTGGAGG AAACCAGTGC ATTGTCCCGA TTTGTAGAAA TAGTTGTGGA 360
GATGGATTTT GTTCCCGTCC TAACATGTGT ACTTGTTCCA GTGGGCAAAT ATCATCAACC 420
TGTGGATCAA AATCAATTCA GCAGTGCAGT GTGAGATGCA TGAATGGTGG GACCTGTGCA 480
GATGACCACT GCCAGTGCCA GAAAGGATAT ATTGGAACTT ATTGTGGACA ACCTGTCTGT 540
GAAAATGGAT GTCAGAATGG TGGACGTTGC ATCGCCCAAC CGTGTGCTTG TGTTTATGGG 600
80 TTCACTGGTC CACAGTGTGA AAGAGATTAC AGGACAGGCC CGTGTTTCAC TCAGGTCAAC 660
AACCAGATGT GCCAAGGGCA GCTGACAGGC ATTGTCTGCA CGAAGACTCT GTGCTGTGCC 720
ACCACTGGAC GGGCGTGGGG CCATCCCTGT GAGATGTGTC CAGCCCAGCC TCAGCCCTGC 780
CGACGGGGTT TCATCCCCAA CATCCGCACT GGAGCTTGCC AAGATGTTGA TGAATGCCAG 840
GCTATCCCAG GGATATGCCA AGGAGGAAAC TGTATCAATA CAGTGGGCTC TTTTGAATGC 900 AGATGCCCTG CTGGTCACAA ACAGAGTGAA ACTACTCAGA AATGTGAAGA CATTGATGAG 960 TGCAGCATCA TTCCTGGGAT ATGTGAAACT GGTGAATGTT CCAACACCGT GGGAAGCTAT 1020 TTTTGTGTTT GTCCACGTGG ATATGTAACC TCAACAGATG GCTCTCGATG CATCGATCAG 1080 AGAACAGGCA TGTGTTTCTC GGGCCTGGTG AATGGCCGCT GTGCACAAGA GCTCCCGGGG 1140 AGAATGACGA AAATGCAGTG CTGCTGTGAG CCTGGCCGCT GCTGGGGCAT CGGAACCATT 1200 CCTGAAGCCT GTCCTGTCAG AGGTTCTGAG GAATATCGCA GACTTTGCAT GGATGGACTT 1260 CCAATGGGAG GAATTCCAGG GAGTGCTGGT TCCAGACCTG GAGGCACTGG GGGAAATGGC 1320 TTTGCCCCAA GTGGCAATGG CAATGGCTAT GGCCCAGGAG GGACAGGCTT CATCCCCATC 1380 CCTGGAGGCA ATGGCTTTTC TCCTGGCGTT GGGGGAGCCG GTGTGGGGGC CGGGGGACAG 1440 GGACCTATCA TCACTGGACT AACAATTCTG AACCAGACAA TAGATATCTG TAAGCATCAT 1500 GCTAACCTTT GTTTAAATGG ACGCTGTATA CCAACTGTCT CAAGCTACCG ATGTGAATGC 1560 AACATGGGTT ATAAGCAGGA TGCAAATGGA GATTGTATAG ATGTTGATGA ATGCACATCA 1620 AATCCCTGCA CTAATGGAGA TTGTGTTAAC ACACCTGGTT CCTATTATTG TAAATGTCAT 1680 GCTGGATTCC AGAGGACTCC TACCAAGCAA GCATGCATTG ATATTGATGA GTGCATCCAG 1740 AATGGGGTTC TTTGTAAAAA CGGTCGATGC GTGAACTCAG ATGGAAGTTT CCAGTGCATT 1800 TGCAATGCCG GCTTTGAATT AACTACAGAT GGAAAAAACT GTGTTGATCA TGATGAATGT 1860 ACAACTACCA ACATGTGTTT GAATGGAATG TGCATCAATG AAGATGGCAβ CTTCAAGTGC 1920 ATCTGCAAAC CAGGATTTGT CTTGGCTCCA AATGGGCGTT ACTGTACTGA TGTTGATGAA 1980 TGCCAGACCC CAGGAATCTG CATGAATGGG CACTGCATCA ACAGTGAAGG GTCCTTCCGC 2040 TGTGACTGTC CCCCAGGCCT GGCTGTGGGC ATGGATGGAC GTGTGTGTGT TGATACTCAC 2100 ATGCGCAGTA CCTGCTATGG AGGAATCAAG AAAGGAGTGT GTGTGCGTCC TTTCCCCGGT 2160 GCAGTGACCA AGTCCGAATG CTGCTGTGCC AATCCAGACT ATGGTTTTGG AGAACCCTGC 2220 CAGCCATGCC CTGCAAAAAA TTCAGCTGAA TTCCACGGCC TTTGTAGTAG TGGAGTAGGT 2280 ATCACTGTGG ATGGAAGAGA TATCAATGAA TGTGCTTTGG ATCCTGATAT ATGTGCCAAT 2340 GGGATTTGTG AAAACTTACG TGGTAGTTAC CGTTGTAATT GCAACAGTGG CTATGAACCA 2400 GATGCCTCTG GAAGAAACTG TATTGACATT GATGAATGTT TAGTAAACAG ACTGCTTTGT 2460 GATAACGGAT TGTGCCGAAA CACGCCAGGA AGTTACAGCT GTACGTGCCC ACCAGGGTAT 2520 GTGTTCAGGA CTGAGACAGA GACCTGTGAA GATATAAATG AATGTGAAAG CAACCCATGT 2580 GTCAATGGGG CCTGCAGAAA CAACCTTGGA TCTTTCAATT GTGAATGTTC GCCCGGCAGC 2640 AAACTCAGCT CCACAGGATT GATCTGTATT GACAGCCTGA AGGGGACCTG TTGGCTCAAC 2700 ATCCAGGACA GCCGCTGTGA GGTGAATATT AATGGAGCCA CTCTGAAATC TGAATGCTGT 2760 GCCACCCTCG GAGCCGCCTG GGGGAGCCCC TGTGAGCGGT GTGAACTAGA TACAGCTTGC 2820 CCAAGAGGGC TTGCCAGGAT TAAAGGTGTT ACGTGTGAAG ATGTTAATGA GTGTGAGGTG 2880 TTCCCTGGCG TTTGTCCAAA TGGACGCTGT GTCAACAGTA AGGGATCTTT TCATTGCGAG 2940 TGCCCTGAAG GCCTTACGTT GGATGGGACT GGCCGTGTAT GTTTGGATAT TCGCATGGAG 3000 CAGTGTTACT TGAAGTGGGA TGAAGATGAA TGCATCCACC CCGTTCCTGG AAAGTTCCGC 3060 ATGGATGCCT GCTGCTGTGC TGTCGGGGCG GCTTGGGGCA CCGAGTGTGA GGAGTGCCCC 3120 AAACCTGGCA CCAAGGAATA CGAGACACTG TGCCCCCGCG GGGCTGGCTT TGCTAACCGA 3180 GGGGATGTTC TTACTGGGCG GCCATTTTAC AAAGACATCA ATGAATGCAA AGCATTTCCT 3240 GGGATGTGCA CTTATGGGAA GTGCAGAAAT ACAATCGGAA GCTTCAAATG CCGTTGCAAT 3300 AGTGGCTTTG CTCTAGACAT GGAGGAAAGA AACTGCACGG ACATCGACGA GTGCAGGATT 3360 TCTCCTGACC TCTGTGGCAG TGGAATCTGC GTCAATACAC CGGGCAGCTT TGAGTGCGAG 3420 TGCTTCGAAG GCTATGAAAG TGGCTTCATG ATGATGAAGA ACTGCATGGA CATTGACGGA 3480 TGTGAACGTA ACCCTCTCCT TTGTAGGGGT GGCACCTGTG TGAACACTGA GGGCAGCTTT 3540 CAGTGTGACT GCCCACTGGG ACACGAGCTG TCACCATCCC GTGAGGACTG TGTGGATATT 3600 AATGAATGCT CCCTGAGTGA CAATCTCTGC AGAAATGGAA AATGTGTGAA CATGATTGGA 3660 ACCTATCAGT GCTCTTGCAA TCCTGGATAT CAGGCTACGC CAGACCGCCA GGGCTGTACA 3720 GATATTGATG AATGTATGAT AATGAACGGA GGCTGTGACA CCCAGTGCAC AAATTCAGAG 3780 GGAAGCTACG AATGCAGCTG CAGTGAGGGT TATGCCCTGA TGCCAGATGG GAGATCGTGT 3840 GCAGACATTG ATGAATGTGA AAACAATCCT GATATCTGTG ATGGCGGCCA GTGTACCAAC 3900 ATTCCTGGAG AGTATCGCTG CCTCTGCTAT GATGGCTTCA TGGCTTCCAT GGACATGAAA 3960 ACATGCATTG ATGTCAATGA ATGTGACCTA AATTCAAATA TCTGCATGTT TGGGGAATGT 4020 GAGAACACAA AGGGATCCTT CATTTGCCAC TGTCAGCTGG GTTACTCAGT GAAGAAGGGG 4080 ACCACAGGAT GTACAGATGT GGATGAGTGT GAAATTGGTG CTCATAACTG CGACATGCAT 4140 GCCTCATGTC TGAATATCCC AGGAAGCTTC AAGTGTAGCT GCAGAGAAGG CTGGATTGGA 4200 AACGGCATCA AGTGTATTGA TCTGGACGAA TGTTCTAATG GAACCCACCA GTGTAGCATC 4260 AATGCTCAGT GTGTAAATAC CCCGGGCTCA TACCGCTGTG CCTGCTCCGA AGGTTTCACT 4320 GGTGATGGCT TTACCTGCTC AGATGTTGAT GAGTGTGCAG AAAACATAAA CCTCTGTGAG 4380 AACGGACAGT GCCTTAATGT CCCGGGTGCA TATCGCTGCG AGTGTGAGAT GGGCTTCACT 4440 CCAGCCTCAG ACAGCAGATC CTGCCAAGAT ATTGATGAAT GCTCCTTCCA AAACATTTGT 4500 GTCTCTGGAA CATGTAATAA CCTGCCTGGA ATGTTTCATT GCATCTGCGA TGATGGTTAT 4560 GAATTGGACA GAACAGGAGG GAACTGTACA GATATTGATG AGTGTGCAGA TCCTATAAAC 4620 TGTGTCAATG GCCTATGTGT CAACACGCCT GGTCGCTATG AGTGTAACTG CCCACCCGAT 4680 TTTCAGTTGA ACCCAACTGG TGTGGGTTGT GTTGACAACC GTGTGGGCAA CTGCTACCTG 4740 AAGTTTGGAC CTCGAGGAGA TGGGAGTCTG TCTTGCAACA CCGAGATCGG GGTGGGCGTC 4800 AGTCGCTCTT CATGCTGCTG CTCTCTGGGA AAGGCCTGGG GAAACCCCTG TGAGACATGC 4860 CCCCCTGTCA ATAGCACTGA ATATTACACC CTGTGTCCCG GAGGTGAAGG CTTCAGACCT 4920 AACCCCATCA CAATCATTTT AGAAGACATT GACGAATGCC AGGAGTTACC AGGTCTCTGC 4980 CAGGGTGGAA ACTGCATCAA CACTTTTGGG AGCTTCCAGT GTGAGTGCCC ACAAGGCTAC 5040 TACCTCAGCG AGGATACCCG CATCTGTGAG GATATTGATG AGTGTTTTGC ACATCCTGGT 5100 GTGTGTGGGC CTGGGACCTG CTATAACACC CTGGGAAATT ACACCTGCAT TTGCCCACCT 5160 GAGTACATGC AGGTCAATGG AGGCCACAAC TGCATGGACA TGAGAAAAAG CTTTTGCTAC 5220 CGAAGCTATA ATGGAACCAC TTGTGAGAAT GAGTTGCCTT TCAATGTGAC AAAAAGGATG 5280 TGCTGCTGCA CATATAATGT GGGCAAAGCT GGGAACAAAC CTTGTGAACC ATGCCCAACT 5340 CCAGGAACAG CTGACTTTAA AACCATATGT GGAAATATTC CTGGATTCAC CTTTGACATT 5400 CACACAGGAA AAGCTGTTGA CATTGATGAA TGTAAAGAGA TTCCAGGCAT TTGTGCAAAT 5460 GGTGTGTGCA TTAACCAGAT TGGCAGTTTC CGCTGTGAAT GCCCTACAGG ATTCAGTTAC 5520 AATGACCTGC TGTTGGTTTG TGAAGATATA GATGAGTGCA GCAATGGTGA TAATCTCTGC 5580 CAGCGGAATG CAGACTGCAT CAATAGTCCT GGTAGTTACC GCTGTGAATG TGCCGCGGGT 5640 TTCAAACTTT CACCCAATGG GGCCTGTGTA GATCGCAATG AATGTTTAGA AATTCCTAAC 5700 GTTTGCAGTC ATGGCTTGTG TGTTGATCTG CAAGGAAGTT ACCAGTGCAT CTGCCACAAT 5760 GGCTTTAAGG CTTCTCAGGA CCAGACCATG TGCATGGATG TTGATGAGTG CGAGCGGCAC 5820 CCATGTGGAA ATGGAACTTG TAAAAACACC GTTGGATCCT ATAACTGTCT GTGCTACCCA 5880 GGGTTTGAAC TCACTCATAA TAATGATTGC CTGGACATAG ATGAGTGCAG TTCCTTTTTT 5940 GGTCAGGTGT GCAGAAATGG ACGTTGTTTT AATGAAATTG GTTCTTTCAA GTGTCTATGT 6000
AACGAAGGTT ATGAACTTAC CCCAGATGGC AAAAACTGTA TAGACACTAA TGAGTGTGTC 6060
GCCCTTCCCG GCTCTTGCTC TCCTGGTACC TGTCAGAATT TGGAGGGATC CTTCAGATGC 6120
ATCTGTCCCC CAGGGTATGA AGTAAAAAGC GAGAACTGCA TTGATATAAA TGAATGTGAT 6180
GAAGATCCCA ACATTTGTCT TTTTGGTTCC TGTACTAATA CTCCAGGGGG CTTCCAGTGC 6240
CTCTGCCCCC CTGGCTTTGT ACTATCTGAT AATGGACGGA GATGCTTTGA TACTCGCCAG 6300
AGCTTCTGCT TCACAAATTT TGAAAATGGA AAGTGTTCTG TACCCAAAGC TTTCAACACC 6360
ACAAAAGCAA AATGCTGCTG TAGTAAGATG CCAGGAGAGG GCTGGGGGGA CCCCTGTGAG 6420
CTGTGCCCCA AAGACGATGA AGTTGCATTT CAGGATTTGT GTCCATATGG CCATGGAACT 6480
GTCCCTAGTC TTCATGATAC ACGTGAAGAT GTCAATGAGT GTCTTGAGAG CCCAGGCATT 6540
TGTTCAAATG GTCAATGTAT CAACACCGAC GGATCTTTTC GCTGTGAATG TCCAATGGGC 6600
TACAACCTTG ACTACACTGG AGTACGCTGT GTGGATACTG ATGAGTGTTC AATCGGCAAT 6660
CCGTGTGGAA ATGGTACATG CACCAATGTT ATTGGGAGTT TTGAATGCAA TTGCAATGAA 6720
GGCTTTGAGC CAGGGCCCAT GATGAATTGT GAAGATATCA ACGAATGTGC CCAGAACCCA 6780
CTGCTGTGTG CTTTACGCTG CATGAACACT TTTGGGTCCT ATGAATGCAC GTGCCCGATT 6840
GGCTATGCCC TCAGGGAAGA TCAAAAGATG TGCAAAGATC TGGATGAATG TGCTGAAGGG 6900
TTACACGACT GTGAATCTAG GGGCATGATG TGTAAGAATC TAATCGGCAC CTTCATGTGC 6960
ATCTGCCCTC CTGGAATGGC CCGAAGGCCC GATGGAGAAG GCTGTGTAGA TGAAAATGAA 7020
TGCAGGACCA AGCCAGGAAT CTGTGAAAAT GGACGTTGTG TTAACATTAT TGGAAGCTAT 7080
AGATGTGAGT GTAATGAAGG ATTCCAGTCA AGTTCTTCAG GCACTGAATG CCTTGACAAT 7140
CGACAGGGTC TCTGCTTTGC AGAGGTACTG CAGACAATAT GTCAAATGGC ATCCAGTAGT 7200
CGCAATCTCG TCACTAAGTC AGAATGCTGC TGTGATGGTG GGCGAGGCTG GGGCCACCAG 7260
TGCGAGCTTT GCCCACTTCC TGGAACTGCC CAGTACAAAA AGATATGTCC TCATGGCCCA 7320
GGATATACAA CTGATGGAAG AGATATTGAT GAATGTAAGG TAATGCCAAA CCTCTGCACC 7380
AATGGTCAGT GCATCAATAC CATGGGCTCA TTCCGATGCT TCTGCAAGGT TGGCTACACC 7440
ACAGACATCA GTGGAACCTC TTGTATAGAC CTTGATGAAT GCTCCCAGTC CCCGAAACCA 7500
TGCAACTACA TCTGCAAGAA CACTGAGGGG AGTTATCAGT GTTCATGTCC GAGGGGGTAT 7560
GTCCTGCAAG AGGATGGAAA GACATGCAAA GACCTTGATG AATGTCAAAC AAAGCAGCAT 7620
AACTGCCAGT TCCTCTGTGT CAACACCCTG GGGGGGTTTA CCTGTAAATG TCCACCTGGT 7680
TTCACACAGC ATCACACTGC TTGTATCGAC AACAACGAAT GTGGGTCTCA ACCTTTGCTT 7740
TGTGGAGGAA AGGGAATCTG TCAAAACACT CCAGGCAGTT TCAGCTGTGA ATGCCAAAGA 7800
GGGTTCTCTC TTGATGCCAC CGGACTGAAC TGTGAAGATG TTGATGAATG TGATGGGAAC 7860
CACAGGTGCC AACACGGCTG CCAGAACATC CTGGGTGGCT ACAGATGTGG CTGCCCCCAA 7920
GGCTACATCC AGCACTACCA GTGGAATCAG TGTGTCGATG AGAATGAATG CTCCAATCCC 7980
AATGCCTGTG GCTCTGCTTC CTGCTACAAC ACCCTGGGGA GTTACAAGTG CGCCTGCCCC 8040
TCGGGGTTCT CCTTCGACCA GTTCTCCAGT GCCTGCCACG ACGTGAATGA GTGCTCGTCC 8100
TCCAAGAACC CCTGCAATTA CGGCTGCTCT AACACGGAGG GGGGCTACCT CTGTGGCTGC 8160
CCCCCTGGGT ATTACAGAGT GGGACAAGGC CACTGTGTCT CAGGAATGGG ATTTAACAAG 8220
GGGCAGTACC TGTCACTGGA TACAGAGGTC GATGAGGAAA ATGCTCTGTC CCCAGAAGCA 8280
TGCTACGAGT GCAAAATCAA CGGCTATCCT AAGAAAGACA GCAGGCAGAA GAGAAGTATT 8340
CATGAACCTG ATCCCACTGC TGTTGAACAG ATCAGCCTAG AGAGTGTCGA CATGGACAGC 8400
CCCGTCAACA TGAAGTTCAA CCTCTCCCAC CTCGGCTCTA AGGAGCACAT CCTGGAACTA 8460
AGGCCCGCCA TCCAGCCCCT CAACAACCAC ATCCGTTATG TCATCTCTCA AGGGAACGAT 8520
GACAGCGTCT TCCGCATCCA CCAAAGGAAT GGGCTCAGCT ACTTGCACAC GGCCAAGAAG 8580
AAGCTCATGC CCGGCACATA CACACTGGAA ATCACTAGCA TCCCTCTCTA CAAGAAGAAG 8640
GAGCTTAAGA AACTGGAAGA GAGCAATGAG GATGACTACC TCCTAGGGGA GCTTGGGGAG 8700
GCTCTCAGAA TGAGGCTGCA GATTCAGCTC TATTAACCGT TCACAGACTT GGGCCCAGGC 8760
TCAAATCCTA GCACAGCCAG TCTGCAGAAG CATTTGAAAA GTCAAGGACT AATTTTAAAG 8820
AGGAAAAATA ATAATAACTC TTGTTTCTTT CCTCCCTGTC TTAGACTTTG AATGTTGACC 8880
CTCACAGGGA GGGATAATTT AGACTCTGGT ATGGCCAAAG ATTTGAGCTC AAAGGCAACC 8940
GTGGTTACTG TATTTTTTAT ATAACTTCAT TTTAAAATAT ATTAAAAGAA ACCTAAATGT 9000
TCAAGATATC AGCATATGGC ACTAAATGCA CAAAAATAAT GTGAGCTTTT TTTTTTTTTT 9060
CCTGTTAGCA GTCTGTAACA CTTTGGGTAT TTTGCTATAG TTGCTAATTA AAAAAATATA 9120
GATGTTTATT TATTTTTAAT GCAGTAATAT ATGGAGAAAT GAACAAACTA TGTAAACAAA 9180
AAGGGAAACT CACTTGTTTT TCTTTAGATT TATAAATTTG AGCTATTTTT TTTAGAGGTG 9240
CTTTTTAAAA ATCCAATAGA TACAAGAGAT GTTTCCTTTG GTTTTCTGCC AGTCATCCAG 9300
CTGATACACA CCTGATCGAT TTTAAAGAAA GCCACACAGA GCTGAATCGG GCAGTGCTAA 9360
TCAATAATTT AAAAGACATG AATGTCATTA GATCCTTTAT AACGTAGATC GAAGCCAAAG 9420
CAGCTCATTT GTGACAACAT TTCATATCAC CAGACACACC AGGCAACAGA AGTTGAAGCA 9480
CAACCACTGT AGCAAAATAC CTTGACTGCT TGTGAGACCA TTAGCATTGC AGGCCAAACC 9540
GTACTGTATT TCCTTCTCAT AACCTCAAGG AACCATATGT GCTACCCACA ACACCTCATT 9600
CTTACCCAGG GTGCGCTGCG TCCTCATGGT ACTGTAGGCA GCTGAAGAAC CGCCGTTCCC 9660
TTGAAAGGGA ACACCTGGCA TTCTGTGGTG TTTCGTGCTG TCTTAAATAA TGGTGCATTT 9720
ATTATGTTCA AGTTATTTCA GGATTGCCAT ATGTGCAAAC AAATCATGCA ATGCAGCCAA 9780
GGAATATATG TTGTTGTTGT TGTTTTAAAC CCATTTTTTT TTTAGAATTT TCATTAATAC 9840
TGTAGTTATA CACCATATGC CTCATTTTAT CATAGCCTAT TGTGTATGAA AGATGTTTGT 9900
ACAATGAATT GATGTTTAGT TTGCTTTAGT CATTTAAAAA GATATTGTAC CAGGATGTGC 9960
TATTAAGAGC ACGTATCCAT TATTCTTCTC AACCCAAGAA CCTGTTTCCT GGACCAGTGA 10020
CCAAACCTCA TATGTGAAAT GGCCAAAGCA CATGCAGGCT CCTGGTTGTT CCTCTCAAAC 10080
CTGTGCTGAC CAAAGATTAG TAACCAGTTA TACCCAGTAT TTTGAGGTTT TATTGTTTTT 10140 TTAATAACTA AAAAAAAACT CGTGCC
Seq ID NO: 162 Protein sequence Protein Accesεion ft: NP 001990.1
11 21 31 41 51
I I I I I
MGRRRRLCLQ LYFLWLGCW LWAQGTAGQP QPPPPKPPRP QPPPQQVRSA TAGSEGGFLA 60 PEYREEGAAV ASRVRRRGQQ DVLRGPNVCG SRFHSYCCPG WKTLPGGNQC IVPICRNSCG 120 DGFCSRPNMC TCSSGQISST CGSKSIQQCS VRCMNGGTCA DDHCQCQKGY IGTYCGQPVC 180 ENGCQNGGRC IAQPCACVYG FTGPQCERDY RTGPCFTQVN NQMCQGQLTG IVCTKTLCCA 240 TTGRAWGHPC EMCPAQPQPC RRGFIPNIRT GACQDVDECQ AIPGICQGGN CINTVGSFEC 300 RCPAGHKQSE TTQKCEDIDE CSIIPGICET GECSNTVGSY FCVCPRGYVT STDGSRCIDQ 360 RTGMCFSGLV NGRCAQELPG RMTKMQCCCE PGRCWGIGTI PEACPVRGSE EYRRLCMDGL 420 PMGGIPGSAG SRPGGTGGNG FAPSGNGNGY GPGGTGFIPI PGGNGFSPGV GGAGVGAGGQ 480
GPIITGLTIL NQTIDICKHH ANLCLNGRCI PTVSSYRCEC NMGYKQDANG DCIDVDECTS 540
NPCTNGDCVN TPGSYYCKCH AGFQRTPTKQ ACIDIDECIQ NGVLCKNGRC VNSDGSFQCI 600
CNAGFELTTD GKNCVDHDEC TTTNMCLNGM CINEDGSFKC ICKPGFVLAP NGRYCTDVDE 660
CQTPGICMNG HCINSEGSFR CDCPPGLAVG MDGRVCVDTH MRSTCYGGIK KGVCVRPFPG 720
AVTKSECCCA NPDYGFGEPC QPCPAKNSAE FHGLCSSGVG ITVDGRDINE CALDPDICAN 780
GICENLRGSY RCNCNSGYEP DASGRNCIDI DECLVNRLLC DNGLCRNTPG ΞYSCTCPPGY 840
VFRTETETCE DINECESNPC VNGACRNNLG SFNCECSPGS KLSSTGLICI DSLKGTCWLN 900
IQDSRCEVNI NGATLKSECC ATLGAAWGSP CERCELDTAC PRGLARIKGV TCEDVNECEV 960
FPGVCPNGRC VNSKGSFHCE CPEGLTLDGT GRVCLDIRME QCYLKWDEDE CIHPVPGKFR 1020
MDACCCAVGA AWGTECEECP KPGTKEYETL CPRGAGFANR GDVLTGRPFY KDINECKAFP 1080
GMCTYGKCRN TIGSFKCRCN SGFALDMEER NCTDIDECRI SPDLCGSGIC VNTPGSFECE 1140
CFEGYESGFM MMKNCMDIDG CERNPLLCRG GTCVNTEGSF QCDCPLGHEL SPSREDCVDI 1200
NECSLSDNLC RNGKCVNMIG TYQCSCNPGY QATPDRQGCT DIDECMIMNG GCDTQCTNSE 1260
GSYECSCSEG YALMPDGRSC ADIDECENNP DICDGGQCTN IPGEYRCLCY DGFMASMDMK 1320
TCIDVNECDL NSNICMFGEC ENTKGSFICH CQLGYSVKKG TTGCTDVDEC EIGAHNCDMH 1380
ASCLNIPGSF KCSCREGWIG NGIKCIDLDE CSNGTHQCSI NAQCVNTPGS YRCACSEGFT 1440
GDGFTCSDVD ECAENINLCE NGQCLNVPGA YRCECEMGFT PASDSRSCQD IDECSFQNIC 1500
VSGTCNNLPG MFHCICDDGY ELDRTGGNCT DIDECADPIN CVNGLCVNTP GRYECNCPPD 1560
FQLNPTGVGC VDNRVGNCYL KFGPRGDGSL SCNTEIGVGV SRSSCCCSLG KAWGNPCETC 1620
PPVNSTEYYT LCPGGEGFRP NPITIILEDI DECQELPGLC QGGNCINTFG SFQCECPQGY 1680
YLSEDTRICE DIDECFAHPG VCGPGTCYNT LGNYTCICPP EYMQVNGGHN CMDMRKSFCY 1740
RSYNGTTCEN ELPFNVTKRM CCCTYNVGKA GNKPCEPCPT PGTADFKTIC GNIPGFTFDI 1800
HTGKAVDIDE CKEIPGICAN GVCINQIGSF RCECPTGFSY NDLLLVCEDI DECSNGDNLC 1860
QRNADCINSP GSYRCECAAG FKLSPNGACV DRNECLEIPN VCSHGLCVDL QGSYQCICHN 1920
GFKASQDQTM CMDVDECERH PCGNGTCKNT VGSYNCLCYP GFELTHNNDC LDIDECSSFF 1980
GQVCRNGRCF NEIGSFKCLC NEGYELTPDG KNCIDTNECV ALPGSCSPGT CQNLEGSFRC 2040
ICPPGYEVKS ENCIDINECD EDPNICLFGS CTNTPGGFQC LCPPGFVLSD NGRRCFDTRQ 2100
SFCFTNFENG KCSVPKAFNT TKAKCCCSKM PGEGWGDPCE LCPKDDEVAF QDLCPYGHGT 2160
VPSLHDTRED VNECLESPGI CSNGQCINTD GSFRCECPMG YNLDYTGVRC VDTDECSIGN 2220
PCGNGTCTNV IGSFECNCNE GFEPGPMMNC EDINECAQNP LLCALRCMNT FGSYECTCPI 2280
GYALREDQKM CKDLDECAEG LHDCESRGMM CKNLIGTFMC ICPPGMARRP DGEGCVDENE 2340
CRTKPGICEN GRCVNIIGSY RCECNEGFQS SSSGTECLDN RQGLCFAEVL QTICQMASSS 2400
RNLVTKSECC CDGGRGWGHQ CELCPLPGTA QYKKICPHGP GYTTDGRDID ECKVMPNLCT 2460
NGQCINTMGS FRCFCKVGYT TDISGTSCID LDECSQSPKP CNYICKNTEG SYQCSCPRGY 2520
VLQEDGKTCK DLDECQTKQH NCQFLCVNTL GGFTCKCPPG FTQHHTACID NNECGSQPLL 2580
CGGKGICQNT PGSFSCECQR GFSLDATGLN CEDVDECDGN HRCQHGCQNI LGGYRCGCPQ 2640
GYIQHYQWNQ CVDENECSNP NACGSASCYN TLGSYKCACP SGFSFDQFSS ACHDVNECSS 2700
SKNPCNYGCS NTEGGYLCGC PPGYYRVGQG HCVSGMGFNK GQYLSLDTEV DEENALSPEA 2760
CYECKINGYP KKDSRQKRSI HEPDPTAVEQ ISLESVDMDS PVNMKFNLSH LGSKEHILEL 2820
RPAIQPLNNH IRYVISQGND DSVFRIHQRN GLSYLHTAKK KLMPGTYTLE ITSIPLYKKK 2880 ELKKLEESNE DDYLLGELGE ALRMRLQIQL Y
Seq ID NO: 163 DNA sequence
Nucleic Acid Accession ft: NM_013372.1
Coding sequence: 63..617
1 11 21 31 41 • 51
I I I I I I
GCGGCCGCAC TCAGCGCCAC GCGTCGAAAG CGCAGGCCCC GAGGACCCGC CGCACTGACA 60
GTATGAGCCG CACAGCCTAC ACGGTGGGAG CCCTGCTTCT CCTCTTGGGG ACCCTGCTGC 120
CGGCTGCTGA AGGGAAAAAG AAAGGGTCCC AAGGTGCCAT CCCCCCGCCA GACAAGGCCC 180
AGCACAATGA CTCAGAGCAG ACTCAGTCGC CCCAGCAGCC TGGCTCCAGG AACCGGGGGC 240
GGGGCCAAGG GCGGGGCACT GCCATGCCCG GGGAGGAGGT GCTGGAGTCC AGCCAAGAGG 300
CCCTGCATGT GACGGAGCGC AAATACCTGA AGCGAGACTG GTGCAAAACC CAGCCGCTTA 360
AGCAGACCAT CCACGAGGAA GGCTGCAACA GTCGCACCAT CATCAACCGC TTCTGTTACG 420
GCCAGTGCAA CTCTTTCTAC ATCCCCAGGC ACATCCGGAA GGAGGAAGGT TCCTTTCAGT 480
CCTGCTCCTT CTGCAAGCCC AAGAAATTCA CTACCATGAT GGTCACACTC AACTGCCCTG 540
AACTACAGCC ACCTACCAAG AAGAAGAGAG TCACACGTGT GAAGCAGTGT CGTTGCATAT 600
CCATCGATTT GGATTAAGCC AAATCCAGGT GCACCCAGCA TGTCCTAGGA ATGCAGCCCC 660
AGGAAGTCCC AGACCTAAAA CAACCAGATT CTTACTTGGC TTAAACCTAG AGGCCAGAAG 720
AACCCCCAGC TGCCTCCTGG CAGGAGCCTG CTTGTGCGTA GTTCGTGTGC ATGAGTGTGG 780
ATGGGTGCCT GTGGGTGTTT TTAGACACCA GAGAAAACAC AGTCTCTGCT AGAGAGCACT 840
CCCTATTTTG TAAACATATC TGCTTTAATG GGGATGTACC AGAAACCCAC CTCACCCCGG 900
CTCACATCTA AAGGGGCGGG GCCGTGGTCT GGTTCTGACT TTGTGTTTTT GTGCCCTCCT 960
GGGGACCAGA ATCTCCTTTC GGAATGAATG TTCATGGAAG AGGCTCCTCT GAGGGCAAGA 1020
GACCTGTTTT AGTGCTGCAT TCGACATGGA AAAGTCCTTT TAACCTGTGC TTGCATCCTC 1080
CTTTCCTCCT CCTCCTCACA ATCCATCTCT TCTTAAGTTG ATAGTGACTA TGTCAGTCTA 1140
ATCTCTTGTT TGCCAAGGTT CCTAAATTAA TTCACTTAAC CATGATGCAA ATGTTTTTCA 1200
TTTTGTGAAG ACCCTCCAGA CTCTGGGAGA GGCTGGTGTG GGCAAGGACA AGCAGGATAG 1260
TGGAGTGAGA AAGGGAGGGT GGAGGGTGAG GCCAAATCAG GTCCAGCAAA AGTCAGTAGG 1320
GACATTGCAG AAGCTTGAAA GGCCAATACC AGAACACAGG CTGATGCTTC TGAGAAAGTC 1380
TTTTCCTAGT ATTTAACAGA ACCCAAGTGA ACAGAGGAGA AATGAGATTG CCAGAAAGTG 1440
ATTAACTTTG GCCGTTGCAA TCTGCTCAAA CCTAACACCA AACTGAAAAC ATAAATACTG 1500
ACCACTCCTA TGTTCGGACC CAAGCAAGTT AGCTAAACCA AACCAACTCC TCTGCTTTGT 1560
CCCTCAGGTG GAAAAGAGAG GTAGTTTAGA ACTCTCTGCA TAGGGGTGGG AATTAATCAA 1620
AAACCKCAGA GGCTGAAATT CCTAATACCT TTCCTTTATC GTGGTTATAG TCAGCTCATT 1680
TCCATTCCAC TATTTCCCAT AATGCTTCTG AGAGCCACTA ACTTGATTGA TAAAGATCCT 1740
GCCTCTGCTG AGTGTACCTG ACAGTAAGTC TAAAGATGAR AGAGTTTAGG GACTACTCTG 1800
TTTTAGCAAG ARATATTKTG GGGGTCTTTT TGTTTTAACT ATTGTCAGGA GATTGGGCTA 1860
RAGAGAAGAC GACGAGAGTA AGGAAATAAA GGGRATTGCC TCTGGCTAGA GAGTAAGTTA 1920
GGTGTTAATA CCTGGTAGAA ATGTAAGGGA TATGACCTCC CTTTCTTTAT GTGCTCACTG 1980
AGGATCTGAG GGGACCCTGT TAGGAGAGCA TAGCATCATG ATGTATTAGC TGTTCATCTG 2040
CTACTGGTTG GATGGACATA ACTATTGTAA CTATTCAGTA TTTACTGGTA GGCACTGTCC 2100 TCTGATTAAA CTTGGCCTAC TGGCAATGGC TACTTAGGAT TGATCTAAGG GCCAAAGTGC 2160 AGGGTGGGTG AACTTTATTG TACTTTGGAT TTGGTTAACC TGTTTTCTTC AAGCCTGAGG 2220 TTTTATATAC AAACTCCCTG AATACTCTTT TTGCCTTGTA TCTTCTCAGC CTCCTAGCCA 2280 AGTCCTATGT AATATGGAAA ACAAACACTG CAGACTTGAG ATTCAGTTGC CGATCAAGGC 2340 TCTGGCATTC AGAGAACCCT TGCAACTCGA GAAGCTGTTT TTATTTCGTT TTTGTTTTGA 2400 TCCAGTGCTC TCCCATCTAA CAACTAAACA GGAGCCATTT CAAGGCGGGA GATATTTTAA 2460 ACACCCAAAA TGTTGGGTCT GATTTTCAAA CTTTTAAACT CACTACTGAT GATTCTCACG 2520 CTAGGCGAAT TTGTCCAAAC ACATAGTGTG TGTGTTTTGT ATACACTGTA TGACCCCACC 2580 CCAAATCTTT GTATTGTCCA CATTCTCCAA CAATAAAGCA CAGAGTGGAT TTAATTAAGC 2640 ACACAAATGC TAAGGCAGAA TTTTGAGGGT GGGAGAGAAG AAAAGGGAAA GAAGCTGAAA 2700 ATGTAAAACC ACACCAGGGA GGAAAAATGA CATTCAGAAC CAGCAAACAC TGAATTTCTC 2760 TTGTTGTTTT AACTCTGCCA CAAGAATGCA ATTTCGTTAA TGGAGATGAC TTAAGTTGGC 2820- AGCAGTAATC TTCTTTTAGG AGCTTGTACC ACAGTCTTGC ACATAAGTGC AGATTTGGCT 2880 CAAGTAAAGA GAATTTCCTC AACACTAACT TCACTGGGAT AATCAGCAGC GTAACTACCC 2940 TAAAAGCATA TCACTAGCCA AAGAGGGAAA TATCTGTTCT TCTTACTGTG CCTATATTAA 3000 GACTAGTACA AATGTGGTGT GTCTTCCAAC TTTCATTGAA AATGCCATAT CTATACCATA 3060 TTTTATTCGA GTCACTGATG ATGTAATGAT ATATTTTTTC ATTATTATAG TAGAATATTT 3120 TTATGGCAAG ATATTTGTGG TCTTGATCAT ACCTATTAAA ATAATGCCAA ACACCAAATA 3180 TGAATTTTAT GATGTACACT TTGTGCTTGG CATTAAAAGA AAAAAACACA CATCCTGGAA 3240 GTCTGTAAGT TGTTTTTTGT TACTGTAGGT CTTCAAAGTT AAGAGTGTAA GTGAAAAATC 3300 TGGAGGAGAG GATAATTTCC ACTGTGTGGA ATGTGAATAG TTAAATGAAA AGTTATGGTT 3360 ATTTAATGTA ATTATTACTT CAAATCCTTT GGTCACTGTG ATTTCAAGCA TGTTTTCTTT 3420 TTCTCCTTTA TATGACTTTC TCTGAGTTGG GCAAAGAAGA AGCTGACACA CCGTATGTTG 3480 TTAGAGTCTT TTATCTGGTC AGGGGAAACA AAATCTTGAC CCAGCTGAAC ATGTCTTCCT 3540 GAGTCAGTGC CTGAATCTTT ATTTTTTAAA TTGAATGTTC CTTAAAGGTT AACATTTCTA 3600 AAGCAATATT AAGAAAGACT TTAAATGTTA TTTTGGAAGA CTTACGATGC ATGTATACAA 3660 ACGAATAGCA GATAATGATG ACTAGTTCAC ACATAAAGTC CTTTTAAGGA GAAAATCTAA 3720 AATGAAAAGT GGATAAACAG AACATTTATA AGTGATCAGT TAATGCCTAA GAGTGAAAGT 3780 AGTTCTATTG ACATTCCTCA AGATATTTAA TATCAACTGC ATTATGTATT ATGTCTGCTT 3840 AAATCATTTA AAAACGGCAA AGAATTATAT AGACTATGAG GTACCTTGCT GTGTAGGAGG 3900 ATGAAAGGGG AGTTGATAGT CTCATAAAAC TAATTTGGCT TCAAGTTTCA TGAATCTGTA 3960 ACTAGAATTT AATTTTCACC CCAATAATGT TCTATATAGC CTTTGCTAAA GAGCAACTAA 4020 TAAATTAAAC CTATTCTTTC AAAAAAAAA
Seq ID NO: 164 Protein sequence Protein Accession it: NP 037504.1
1 11 21 31 41 51
I I I I I I
MSRTAYTVGA LLLLLGTLLP AAEGKKKGSQ GAIPPPDKAQ HNDSEQTQSP QQPGSRNRGR 60 GQGRGTAMPG EEVLESSQEA LHVTERKYLK RDWCKTQPLK QTIHEEGCNS RTIINRFCYG 120 QCNSFYIPRH IRKEEGSFQS CSFCKPKKFT TMMVTLNCPE LQPPTKKKRV TRVKQCRCIS 180 IDLD
Seq ID NO: 165 DNA sequence
Nucleic Acid Accession ft: CAT cluster
1 11 21 31 41 51
I I I I I I
GAATTGCATC GGACAGAGCT TCGCCATGGC CGAGTTGCGC GTGGTTGTGG CACTAACACT 60 GCTACGTTTC CGCCTGAGCG TGGACCGAAC GCGCAAGGTG CGGCGGAAGC CGGAGCTCAT 120 ACTGCGCACG GAGAACGGGC TCTGGCTCAA G
Seq ID NO: 166 DNA sequence
Nucleic Acid Accession #: FGENESH predicted
Coding sequence: 1..1650
11 21 31 41 51
I I I I I
ATGCCACCTC TGCCATCCAG AATGTCTCGG GGGCCCTCCT TGGTGACAGG CAGGATGCTG 60 CCCATCACAG ACCGCCTGCT GCACCTCCTG GGGCTGGAGA AGACGGCGTT CCGCATATAC 120 GCGGTGTCCA CCCTTCTCCT CTTCCTGCTC TTCTTCCTGT TCCGCCTGCT GCTGCGGTTC 180 CTGAGGCTCT GCAGGAGCTT CTACATCACC TGCCGCCGGC TGCGCTGCTT CCCCCAGCCT 240 CCCCGGCGCA ACTGGCTGCT GGGCCACCTG GGCATGTACC TTCCAAATGA GGCGGGCCTT 300 CAAGATGAGA AGAAGGTACT GGACAACATG CACCATGTAC TCTTGGTATG GATGGGACCT 360 GTCCTGCCGC TGTTGGTTCT GGTGCACCCT GATTACATCA AACCCCTTTT GGGAGCCTCA 420 GCTGCCATCG CCCCCAAGGA TGACCTCTTC TATGGCTTCC TAAAACCTTG GCTAGGGGAT 480 GGGCTGCTGC TCAGCAAAGG TGACAAGTGG AGCCGGCACC GTCGCCTGCT GACACCCGCC 540 TTCCACTTTG ACATCCTGAA GCCTTACATG AAGATCTTCA ACCAGAGCGC TGACATTATG 600 CATGCTAAAT GGCGGCATCT GGCAGAGGGC TCAGCGGTCT CCCTTGATAT GTTTGAGCAT 660 ATCAGCCTCA TGACCCTGGA CAGTCTTCAG AAATGTGTCT TCAGCTACAA CAGCAACTGC 720 CAAGAGAAGA TGAGTGATTA TATCTCCGCT ATCATTGAAC TGAGCGCTCT GTCTGTCCGG 780 CGCCAGTATC GCTTGCACCA CTACCTCGAC TTCATTTACT ACCGCTCGGC GGATGGGCGG 840 AGGTTCCGGC AGGCCTGTGA CATGGTGCAC CACTTCACCA CTGAAGTCAT CCAGGAACGG 900 CGGCGGGCAC TGCGTCAGCA GGGGGCCGAG GCCTGGCTTA AGGCCAAGCA GGGGAAGACC 960 TTGGACTTTA TTGATGTGCT GCTCCTGGCC AGGGATGAAG ATGGAAAGGA ACTGTCAGAC 1020 GAGGATATCC GAGCCGAAGC AGACACCTTC ATGTTTGAGG GTCACGACAC AACATCCAGT 1080 GGGATCTCTT GGATGCTGTT CAATTTGGCA AAGTATCCGG AATACCAGGA GAAATGCCGA 1140 GAAGAGATTC AGGAAGTCAT GAAAGGCCGG GAGCTGGAGG AGCTGGAGTG GGACGATCTG 1200 ACTCAGCTGC CCTTTACAAC TATGTGCATT AAGGAGAGCC TGCGCCAGTA CCCACCTGTC 1260 ACTCTTGTCT CTCGCCAATG CACGGAGGAC ATCAAGCTCC CAGATGGGCG CATCATCCCC 1320 AAAGGAATCA TCTGCTTGGT CAGCATCTAT GGAACCCACC ACAACCCCAC AGTGTGGCCT 1380 GACTCCAAGG TGTACAACCC CTACCGCTTT GACCCGGACA ACCCACAGCA GCGCTCTCCA 1440 CTGGCCTATG TGCCCTTCTC TGCAGGACCC AGGAATTGCA TCGGACAGAG CTTCGCCATG 1500
GCCGAGTTGC GCGTGGTTGT GGCACTAACA CTGCTACGTT TCCGCCTGAG CGTGGACCGA 1560
ACGCGCAAGG TGCGGCGGAA GCCGGAGCTC ATACTGCGCA CGGAGAACGG GCTCTGGCTC 1620 AAGGTGGAGC CGCTGCCTCC GCGGGCCTGA
Seq ID NO: 167 Protein sequence
Protein Accession #: FGENESH predicted
1 11 21 31 41 51
1 1 1 | 1 | 1 | 1
MPPLPSRMSR GPSLVTGRML PITDRLLHLL GLEKTAFRIY AVSTLLLFLL FFLFRLLLRF 60
LRLCRSFYIT CRRLRCFPQP PRRNWLLGHL GMYLPNEAGL QDEKKVLDNM HHVLLVWMGP 120
VLPLLVLVHP DYIKPLLGAS AAIAPKDDLF YGFLKPWLGD GLLLSKGDKW SRHRRLLTPA 180
FHFDILKPYM KIFNQSADIM HAKWRHLAEG SAVSLDMFEH ISLMTLDSLQ KCVFSYNSNC 240
QEKMSDYISA IIELSALSVR RQYRLHHYLD FIYYRSADGR RFRQACDMVH HFTTEVIQER 300
RRALRQQGAE AWLKAKQGKT LDFIDVLLLA RDEDGKELSD EDIRAEADTF MFEGHDTTSS 360
GISWMLFNLA KYPEYQEKCR EEIQEVMKGR ELEELEWDDL TQLPFTTMCI KESLRQYPPV 420
TLVSRQCTED IKLPDGRIIP KGIICLVSIY GTHHNPTVWP DSKVYNPYRF DPDNPQQRSP 480
LAYVPFSAGP RNCIGQSFAM AELRWVALT LLRFRLSVDR TRKVRRKPEL ILRTENGLWL 540
KVEPLPPRA
Seq ID NO: 168 DNA sequence
Nucleic Acid Accession #: AK058088.1 Coding sequence: 252..1772
60
120
Figure imgf001021_0001
180
CCTGTGGTGG GCAAAAGGGC TTTGGAACGG TTGCTTGTCT TTTCTCTCCT GCGTAATTTC 240
CACTTTCATT CATGATAATG TCGAACACGC ACAAAGCTCG GCTGGAACGC CGGGTCACTG 300
GCTCAACCAA CCGGTGGCGT TTGCCCAAAC AGCCTTTCTC TGGGGACCTG CTCTCACTTT 360
CCCAGATGTG CAAGGCTCTG AGCATAGACT TTGAGGAAGC TTTGAGGAAC CCAGACAGGT 420
TATGCATTTC ACAAATCCAG AAGTTTTTCT TTGAGAATTT CAAGAACAAG GACATCCAAA 480
GTGGGGAAGC AGATGTGATT CTCGAGTGCC TGGGCTTCAA ATGGGAGCTC CATCAGCCCC 540
GGCTTTTTCA GTCTGAGACC TTGGCCAAGC TCTACCTGAA AGCCCTGGCG CAGGGCACCA 600
CACACCCCCT GAGGGAGCTG GAGGAGCTTC TGCGAGCTCA ATCACCTAAG AAGACCAAAG 660
AAAAATCCCC TGCAAAGAGG ATCATCATTT CCTTGAAGAT CAATGACCCA CTGGTCACTA 720
AAGTCGCCTT CGCCACGGCC CTGAAGAACC TCTACATGAG TGAGGTGGAG ATTAACTTGG 780
AAGACCTACT GGGAGTGCTG GCTTCCGCCC ACATCCTCCA GTTCAGTGGC CTGTTTCAAA 840
GGTGCGTGGA TGTGATGATA GCCAGACTCA AGCCAAGCAC CATCAAGAAA TTCTACGAGG 900
CCGGCTGCAA GTACAAGGAA GAGCAGCTCA CCACCGGCTG CGAGAAGTGG CTGGAAATGA 960
ACTTGGTTCC TCTAGGGGGG ACGCAGATCC ACCTCCACAA AATCCCACAG GACCTGCTCC 1020
ACAAAGTGCT GAAGTCCCCC AGGTTATTTA CCTTTAGTGA ATTCCATCTT CTGAAAACAA 1080
TGCTTTTGTG GGTCTTCTTG CAACTGAACT ACAAGATTCA GGCAATTCCG ACTTATGAAA 1140
CCGTGATGAC ATTTTTTAAG AGCTTTCCTG AGAACTGTTG CTTTCTGGAC CGGGACATAG 1200
GACGGAGCTT GAGGCCGCTC TTCCTCTGCT TGCGTCTGCA CGGCATCACC AAAGGCAAGG 1260
ATCTGGAGGT GCTGCGGCAC CTTAACTTCT TCCCAGAGTC ATGGCTCGAC CAGGTTACAG 1320
TCAACCATTA CCACGCACTG GAGAATGGGG GCGACATGGT CCACCTGAAA GATCTTAACA 1380
CCCAGGCTGT GAGATTTGGG CTGCTCTTTA ACCAGGAGAA TACAACTTAT TCGAAAACGA 1440
TTGCTCTATA TGGATTCTTC TTTAAGATAA AGGGACTCAA ACATGATACT ACCTCTTATA 1500
GTTTTTACAT GCAGAGAATA AAGCACACAG ACCTGGAATC TCCCTCTGCG GTCTACGAGC 1560
ACAACCACGT CAGCCTGCGA GCGGCACGCC TGGTGAAGTA TGAGATCAGA GCAGAGGCCC 1620
TGGTTGACGG CAAGTGGCAG GAGTTCAGGA CAAACCAGAT CAAGCAGAAG TTTGGGTTGA 1680
CCACGTCATC CTGCAAAAGC CATACCTTGA AAATCCAAAC TGTGGGCATC CCAATCTATG 1740
TAAGTTTTGC ATTCATCTTC CCAGCATCTT GACAGTTTCC AGAAGAATCT ATGGGATTTT 1800
CCCCCCACTG GTCTGCATAA AAGAAAATAA AATGACATAA AAGGGAGC
Seq ID NO: 169 Protein sequence
Protein Accession #: BAB71658.1
IS 60
Figure imgf001021_0002
PL 120
RELEELLRAQ SPKKTKEKSP AKRIIISLKI NDPLVTKVAF ATALKNLYMS EVEINLEDLL 180
GVLASAHILQ FSGLFQRCVD VMIARLKPST IKKFYEAGCK YKEEQLTTGC EKWLEMNLVP 240
LGGTQIHLHK IPQDLLHKVL KSPRLFTFSE FHLLKTMLLW VFLQLNYKIQ AIPTYETVMT 300
FFKSFPENCC FLDRDIGRSL RPLFLCLRLH GITKGKDLEV LRHLNFFPES WLDQVTVNHY 360
HALENGGDMV HLKDLNTQAV RFGLLFNQEN TTYSKTIALY GFFFKIKGLK HDTTSYSFYM 420
QRIKHTDLES PSAVYEHNHV SLRAARLVKY EIRAEALVDG KWQEFRTNQI KQKFGLTTSS 480
CKSHTLKIQT VGIPIYVSFA FIFPAS
Seq ID NO: 170 DNA sequence
Nucleic Acid Accession #: NM_007000.1 Coding sequence: 1...777
1 11 21 31 41 51
I I I I I I
ATGGCGTCTG CGGCAGCAGC GGAGGCCGAG AAGGGATCTC CAGTTGTGGT GGGCCTGCTA 60
GTTGTGGGCA ATATCATTAT TCTGCTGTCA GGCCTGTCCC TGTTTGCTGA GACCATATGG 120
GTGACAGCCG ACCAGTACCG TGTATACCCA CTGATGGGAG TCTCAGGCAA GGATGACGTC 180
TTCGCTGGTG CCTGGATTGC CATCTTCTGC GGCTTCTCCT TCTTCATGGT AGCCAGTTTT 240 GGTGTGGGTG CCGCACTCTG CCGCCGCCGG TCCATGGTCC TCACGTACCT GGTGCTCATG 300
CTCATCGTCT ACATCTTCGA GTGCGCCTCC TGCATCACGT CCTACACCCA CCGTGACTAC 360
ATGGTGTCCA ACCCATCCCT GATCACCAAG CAGATGCTGA CCTTCTACAG CGCGGACACC 420
GACCAGGGCC AGGAGCTGAC CCGCCTCTGG GACCGCGTCA TGATTGAGCA AGAATGCTGT 480
GGCACATCTG GTCCCATGGA CTGGGTGAAC TTCACGTCAG CCTTCCGGGC GGCCACTCCG 540
GAGGTGGTGT TCCCCTGGCC CCCACTGTGC TGTCGCCGGA CGGGAAACTT CATCCCCCTC 600
AACGAGGAGG GCTGCCGCCT GGGGCACATG GACTACCTGT TCACCAAGGG CTGCTTCGAA 660
CACATCGGCC ACGCCATCGA CAGCTACACG TGGGGTATCT CGTGGTTTGG GTTTGCCATC 720 CTGATGTGGA CGCTCCCGGT CATGCTGATA GCCATGTATT TCTACACCAT GCTCTGA 0
Seq ID NO: 171 Protein sequence Protein Accession ft: NP 008931.1
1 11 21 31 41 51 5 I I I I I I
MASAAAAEAE KGSPWVGLL WGNIIILLS GLSLFAETIW VTADQYRVYP LMGVSGKDDV 60
FAGAWIAIFC GFSFFMVASF GVGAALCRRR SMVLTYLVLM LIVYIFECAS CITSYTHRDY 120
MVSNPSLITK QMLTFYSADT DQGQELTRLW DRVMIEQECC GTSGPMDWVN FTSAFRAATP 180
EWFPWPPLC CRRTGNFIPL NEEGCRLGHM DYLFTKGCFE HIGHAIDSYT WGISWFGFAI 240 0 LMWTLPVMLI AMYFYTML
Seq ID NO: 172 DNA sequence
Nucleic Acid Accession if: NM_006760.1
Coding sequence: 39.-593 5
1 11 21 31 41 51
I I I I I I
GAAAGCCTGC CAGCACCTAT TCCACCTCCC AGCCCAGCAT GGCACCCCTG CTGCCCATCC 60
GGACCTTGCC CTTGATCCTG ATTCTGCTGG CTCTGCTGTC CCCAGGGGCT GCAGACTTCA 120 0 ACATCTCAAG CCTCTCTGGT CTGCTGTCCC CGGCGCTAAC GGAGAGCCTG CTGGTTGCCT 180
TGCCCCCCTG TCACCTCACA GGAGGCAATG CCACACTGAT GGTCCGGAGA GCCAATGACA 240
GCAAAGTGGT GACGTCCAGC TTTGTGGTGC CTCCGTGCCG TGGGCGCAGG GAACTGGTGA 300
GTGTGGTGGA CAGTGGTGCT GGCTTCACAG TCACTCGGCT CAGTGCATAC CAGGTGACAA 360
ACCTCGTGCC AGGAACCAAA TTCTACATTT CCTACCTAGT GAAGAAGGGG ACAGCCACTG 420 5 AGTCCAGCAG AGAGATCCCA ATGTCCACAC TCCCTCGAAG GAACATGGAA TCCATTGGGC 480
TGGGTATGGC CCGCACAGGG GGCATGGTGG TCATCACGGT GCTGCTCTCT GTCGCCATGT 540
TCCTGCTGGT GCTGGGCTTC ATCATTGCCC TGGCACTGGG CTCCCGCAAG TAAGGAGGTC 600
TGCCCGGAGC AGCAGCTTCT CCAGGAAGCC CAGGGCACCA TCCAGCTCCC CAGCCCACCT 660
GCTCCCAGGC CCCAGGCCTG TGGCTCCCTT GGTGCCCTCG CCTCCTCCTC CTGCCCTCCT 720 0 CTCCCCTAGA GCCCTCTCCT CCCTCTGTCC CTCTCCTTGC CCCCAGTGCC TCACCTTCCA 780
ACACTCCATT ATTCCTCTCA CCCCACTCCT GTCAGAGTTG ACTTTCCTCC CATTTTACCA 840
CTTTAAACAC CCCCATAACA ATTCCCCCAT CCTTCAGTGA ACTAAGTCCC TATAATAAAG 900 GCTGAGGCTG CATCTGCCAA AAAAAAAAAA AA 5 Seq ID NO: 173 Protein sequence Protein Accession ft: NP_006751.1
1 11 21 31 41 51 0 I I I I I I
MAPLLPIRTL PLILILLALL SPGAADFNIS SLSGLLSPAL TESLLVALPP CHLTGGNATL 60
MVRRANDSKV VTSSFWPPC RGRRELVSW DSGAGFTVTR LSAYQVTNLV PGTKFYISYL 120
VKKGTATESS REIPMSTLPR RNMESIGLGM ARTGGMWIT VLLSVAMFLL VLGFIIALAL 180
GSRK 5 Seq ID NO: 174 DNA sequence
Nucleic Acid Accession #: Eos sequence Coding sequence: 1..2733
,,_ 1 11 21 31 41 51
60 i i i i i i
ATGAAAGTTG GAGTGCTGTG GCTCATTTCT TTCTTCACCT TCACTGACGG CCACGGTGGC 60
TTCCTGGGGA AAAATGATGG CATCAAAACA AAAAAAGAAC TCATTGTGAA TAAGAAAAAA 120
CATCTAGGCC CAGTCGAAGA ATATCAGCTG CTGCTTCAGG TGACCTATAG AGATTCCAAG 180
GAGAAAAGAG ATTTGAGAAA TTTTCTGAAG CTCTTGAAGC CTCCATTATT ATGGTCACAT 240
65 GGGCTAATTA GAATTATCAG AGCAAAGGCT ACCACAGACT GCAACAGCCT GAATGGAGTC 300
CTGCAGTGTA CCTGTGAAGA CAGCTACACC TGGTTTCCTC CCTCATGCCT TGATCCCCAG 360
AACTGCTACC TTCACACGGC TGGAGCACTC CCAAGCTGTG AATGTCATCT CAACAACCTC 420
AGCCAGAGTG TCAATTTCTG TGAGAGAACA AAGATTTGGG GCACTTTCAA AATTAATGAA 480
AGGTTTACAA ATGACCTTTT GAATTCATCT TCTGCTATAT ACTCCAAATA TGCAAATGGA 540
70 ATTGAAATTC AACTTAAAAA AGCATATGAA AGAATTCAAG GTTTTGAGTC GGTTCAGGTC 600
ACCCAATTTC GAAATGGAAG CATCGTTGCT GGGTATGAAG TTGTTGGCTC CAGCAGTGCA 660
TCTGAACTGC TGTCAGCCAT TGAACATGTT GCCGAGAAGG CTAAGACAGC CCTTCACAAG 720
CTGTTTCCAT TAGAAGACGG CTCTTTCAGA GTGTTCGGAA AAGCCCAGTG TAATGACATT 780
GTCTTTGGAT TTGGGTCCAA GGATGATGAA TATACCCTGC CCTGCAGCAG TGGCTACAGG 840
75 GGAAACATCA CAGCCAAGTG TGAGTCCTCT GGGTGGCAGG TCATCAGGGA GACTTGTGTG 900
CTCTCTCTGC TTGAAGAACT GAACAAGAAT TTCAGTATGA TTGTAGGCAA TGCCACTGAG 960
GCAGCTGTGT CATCCTTCGT GCAAAATCTT TCTGTCATCA TTCGGCAAAA CCCATCAACC 1020
ACAGTGGGGA ATCTGGCTTC GGTGGTGTCG ATTCTGAGCA ATATTTCATC TCTGTCACTG 1080
GCCAGCCATT TCAGGGTGTC CAATTCAACA ATGGAGGATG TCATCAGTAT AGCTGACAAT 1140
80 ATCCTTAATT CAGCCTCAGT AACCAACTGG ACAGTCTTAC TGCGGGAAGA AAAGTATGCC 1200
AGCTCACGGT TACTAGAGAC ATTAGAAAAC ATCAGCACTC TGGTGCCTCC GACAGCTCTT 1260
CCTCTGAATT TTTCTCGGAA ATTCATTGAC TGGAAAGGGA TTCCAGTGAA CAAAAGCCAA 1320
CTCAAAAGGG GTTACAGCTA TCAGATTAAA ATGTGTCCCC AAAATACATC TATTCCCATC 1380
AGAGGCCGTG TGTTAATTGG GTCAGACCAA TTCCAGAGAT CCCTTCCAGA AACTATTATC 1440 AGCATGGCCT CGTTGACTCT GGGGAACATT CTACCCGTTT CCAAAAATGG AAATGCTCAG 1500 GTCAATGGAC CTGTGATATC CACGGTTATT CAAAACTATT CCATAAATGA AGTTTTCCTA 1560 TTTTTTTCCA AGATAGAGTC AAACCTGAGC CAGCCTCATT GTGTGTTTTG GGATTTCAGT 1620 CATTTGCAGT GGAACGATGC AGGCTGCCAC CTAGTGAATG AAACTCAAGA CATCGTGACG 1680 TGCCAATGTA CTCACTTGAC CTCCTTCTCC ATATTGATGT CACCTTTTGT CCCCTCTACA 1740 ATCTTCCCCG TTGTAAAATG GATCACCTAT GTGGGACTGG GTATCTCCAT TGGAAGTCTC 1800 ATTTTATGCC TGATCATCGA GGCTTTGTTT TGGAAGCAGA TTAAAAAAAG CCAAACCTCT 1860 CACACACGTC GTATTTGCAT GGTGAACATA GCCCTGTCCC TCTTGATTGC TGATGTCTGG 1920 TTTATTGTTG GTGCCACAGT GGACACCACG GTGAACCCTT CTGGAGTCTG CACAGCTGCT 1980 GTGTTCTTTA CACACTTCTT CTACCTCTCT TTGTTCTTCT GGATGCTCAT GCTTGGCATC 2040 CTGCTGGCTT ACCGGATCAT CCTCGTGTTC CATCACATGG CCCAGCATTT GATGATGGCT 2100 GTTGGATTTT GCCTGGGTTA TGGGTGCCCT CTCATTATAT CTGTCATTAC CATTGCTGTC 2160 ACGCAACCTA GCAATACCTA CAAAAGGAAA GATGTGTGTT GGCTTAACTG GTCCAATGGA 2220 AGCAAACCAC TCCTGGCTTT TGTTGTCCCT GCACTGGCTA TTGTGGCTGT GAACTTCGTT 2280 GTGGTGCTGC TAGTTCTCAC AAAGCTCTGG AGGCCGACTG TTGGGGAAAG ACTGAGTCGG 2340 GATGACAAGG CCACCATCAT CCGCGTGGGG AAGAGCCTCC TCATTCTGAC CCCTCTGCTA 2400 GGGCTCACCT GGGGCTTTGG AATAGGAACA ATAGTGGACA GCCAGAATCT GGCTTGGCAT 2460 GTTATTTTTG CTTTACTCAA TGCATTCCAG GGATTTTTTA TCTTATGCTT TGGAATACTC 2520 TTGGACAGTA AGCTGCGACA ACTTCTGTTC AACAAGTTGT CTGCCTTAAG TTCTTGGAAG 2580 CAAACAGAAA AGCAAAACTC ATCAGATTTA TCTGCCAAAC CCAAATTCTC AAAGCCTTTC 2640 AACCCACTGC AAAACAAAGG CCATTATGCA TTTTCTCATA CTGGAGATTC CTCCGACAAC 2700 ATCATGCTAA CTCAGTTTGT CTCAAATGAA TAA
Seq ID NO: 175 Protein sequence Protein Accession it : Eos sequence
11 21 31 41 51
I I I I I
MKVGVLWLIS FFTFTDGHGG FLGKNDGIKT KKELIVNKKK HLGPVEEYQL LLQVTYRDSK 60 EKRDLRNFLK LLKPPLLWSH GLIRIIRAKA TTDCNSLNGV LQCTCEDSYT WFPPSCLDPQ 120 NCYLHTAGAL PSCECHLNNL SQSVNFCERT KIWGTFKINE RFTNDLLNSS SAIYSKYANG 180 IEIQLKKAYE RIQGFESVQV TQFRNGSIVA GYEWGSSSA SELLSAIEHV AEKAKTALHK 240 LFPLEDGSFR VFGKAQCNDI VFGFGSKDDE YTLPCSSGYR GNITAKCESS GWQVIRETCV 300 LSLLEELNKN FSMIVGNATE AAVSSFVQNL SVIIRQNPST TVGNLASWS ILSNISSLSL 360 ASHFRVSNST MEDVISIADN ILNSASVTNW TVLLREEKYA SSRLLETLEN ISTLVPPTAL 420 PLNFSRKFID WKGIPVNKSQ LKRGYSYQIK MCPQNTSIPI RGRVLIGSDQ FQRSLPETII 480 SMASLTLGNI LPVSKNGNAQ VNGPVISTVI QNYSINEVFL FFSKIESNLS QPHCVFWDFS 540 HLQWNDAGCH LVNETQDIVT CQCTHLTSFS ILMSPFVPST IFPWKWITY VGLGISIGSL 600 ILCLIIEALF WKQIKKSQTS HTRRICMVNI ALSLLIADVW FIVGATVDTT VNPSGVCTAA 660 VFFTHFFYLS LFFWMLMLGI LLAYRIILVF HHMAQHLMMA VGFCLGYGCP LIISVITIAV 720 TQPSNTYKRK DVCWLNWSNG SKPLLAFWP ALAIVAVNFV WLLVLTKLW RPTVGERLSR 780 DDKATIIRVG KSLLILTPLL GLTWGFGIGT IVDSQNLAWH VIFALLNAFQ GFFILCFGIL 840 LDSKLRQLLF NKLSALSSWK QTEKQNSSDL SAKPKFSKPF NPLQNKGHYA FSHTGDSSDN 900 IMLTQFVSNE
Seq ID NO: 176 DNA sequence
Nucleic Acid Accession ft: AB035089.1
Coding sequence: 9845..10219
1 11 21 31 41 51 ] 1 1 | 1 | 1 | 1 1 GGGCATGCAG CCATCGGGGA AAATCCATAG TGCAGATAAA GCAAGGAGGA AGAAGAAGGA 60
CAGTTCTAGT AAAAGGGAGA ACATCAATAT AGGATGTTTC TTAGCAATAG AAAAAGAAGG 120
CCAAGAGGAA TTAGGGAGAG AGTTATAAGA GATCAGCAAG GGGACAGGGT TAGATTTGGT 180
TTGGTTTGAA AGCATACAGT AAATATGATG TCTGTCCCTG GCAGTGTTGG CAGAGTAGGA 240
AGGAGGAAGG GAGGCAAGAG ATAATATCAT TTTCTCTGTG CTCCAACTGT ACTTACATAT 300
GAGACTATTT CCCTCTCTGC TTTTCAAACC TTACTGGAGT TGTTTTCCCT CATGAAAACC 360
AAGAAAGGAA AGCTAGTTAG TCTTGTTCTG AGGTTGTTCA ATGTATACAT ATCTATATCT 420
GTAGACAGAA TCCTTGGGAA TACAGTAATT GACATATATT CTGTTATTTG ATGCTTGAAA 480
AATCTCCTCC ACTAACCAGT TTCCCTATAG ATTGCCACAA GCACATAATA AGAAACAATA 540
AATAAAATGT TCTCTTGACT TTGTTACTTA ACAATGCTGA GAAAACTTTA CAGCCTTCAT 600
AAGGAAGTGA GGTCCAGGAA AATCTAGGAG ATATTTCTTA ACCAATCTAT AAAGGCATTA 660
GTAATGACAG GATATTTCCT GAAAGTGTAA TTTCCCATTG AGGATTTGTT TTTAATTTCT 720
GGATTCCTGG AGCCAATGAA GTTGGTGTAT GTTTATGAAA TATCAAGAGA CATAAGTTGG 780
CAAGTGTTCA TATGCAAAAA CTTCTTGGAA TTTCTGAGTT CTCTGTGGCA ATATATGACA 840
TCAGGATATG TCCAGTCTCA CACACCAGGA TATGTCCTTT CTAGCCTGTC TATCACATGC 900
TAGGAGAACT ATTTAGGAAC AGAAAAAAAT GCCTGAAATG ATTTCTCATT TGAACTCATC 960
CAAGCTTTCT CTAAATTTAA GCAAACTCCT GGTCATTTTC AGTTAGTACC TTTCCTTAAG 1020
TTCAACCTTC AGGGCAAACC TCCGTGCCTC AGACGTTTAG CCATAGTCTG AAATTCTCTT 1080
CCATAGATTG GTCCCCTGTA ACCCCGGTTT GTCTCAGCTT GTTATCCTGT TTTTTTCTTC 1140
CCTCCATTCC CAGGATGAGC TTGTTGCTTC TGTCCTATGA GACATTAGAT TCCTTTTCTT 1200
TGGTACCCGA GTAAATCCAT CCTACTCCAA TAGAGGAAGG TCCATTTTTG TCTTATAGCG 1260
CTGGATGCAG ACTCAGCTGA GAAGACCATT ATTCATTTTT GGAATTCTTT ATCTCAGATA 1320
TTTCCTCTTC TTTCTTTTTC TTCTATCTTT GGATTTTTAG TCCATCAACG CCCCATTAGT 1380
CTATTCCCCG ACTTCAATCA GGGAACTTAT ACCTCTTAAA CTCATTCAGA GACTCAAAAC 1440
ATATATATTG ATACAGGAGA CCTAAGAAGA GCATGTCTTG GGGGTTGAGG AAACAGGCAG 1500
GTGAGAAATT TCCAGATTGG AAACACAGCT TCCTTTCTCC CATCCAGCCC CTACTTTCAG 1560
CCTATGTGTT TCTGGCACCT TGTTGTAGAT AAATCTCCCT TGACTTTGTG ATGTGCTGAG 1620
AAAACAAACT CACGGCTGGT GTTAAAAAGG GCCCATGACA ATACCAAGTG TTGGGGAGAA 1680
TGTGGAGAAA TCAGAACTCT ATTCACGGTC GGTTGGAATG CACACTTGTG CAGAATTCTA 1740
TGGAGAAGAG TCTGGCATTT CCTCAAAATG TTAACCTGGA TTTACCATAT GACCCAGCGA 1800
TTTCATTCAT AGGTTTATAC TCAAAAGAAA TGAAGAAATA TGCCATGCAA AAAAATGTAC 1860
ATGAAAGGTC ACAACATCAT TATTCATAAT AGTAAAAGGA TGGAAACAAC ACAAATGTCC 1920
ATCAACTTAT GATTAAAGAA AATCTGGTCT ATTCATAGAA TGGAATATTA TTCGACCACA 1980 AAAAGGAATG ATGTACTGAT CCATGCAATG ATGTGGACAA ACCATGAAAA TAACACTAGA 2040 TTAAAGAAGC CAGTCACAAA AGGACTTACT GTATGATTCC ATTTACCTGA AATGTTTGGA 2100 ATAGGCAAAT CCATAGAAAC AGGAGGTAGA TTCCTGGTTT CCAGGGTCTC CAGGAAGGGA 2160 AGAATGAAGT ACAAGATTTC TTTTGGAGGT AGTGAAATTG TTGTGGAATG AGATCATGAT 2220 GATGATAGCA CAACTTTGTG AATATAATAA AATCATTGAA TTGTACAGTT GAATTTATGG 2280 TATATAAATT ATATGTTAAT AAAAAGGGGG TCCACAAAAC AAACAGCCCC CCACTCTGGT 2340 TGTCAGGGAG ATATTGGATT AAATGGCCTT GGACAACAAC CCCTCTCCCT GGCCACAGAC 2400 ATTCTTCAGA TTACAAGATA TTCCAGGGGA AACACTGGAA TGAGTCTGAA GCCAGGTGCT 2460 AAACAGAAGG ACCATTGAGA AATGTTGTGA TCCTGACAGG TCAAGCAATT TATTTTTCGG 2520 CTTCATTTTT AAATGTAAAA TTAGAAAGCT GCCATTTAAA ATGGCCCGTC TGTTTCAATT 2580 GCTCTTCTCA GTGTCAGCCT GTTAACTCAA TGTGTTAGTC TGTTTTCATG CTGCTGATAA 2640 AAACATACCT GAGACTGGCA AGAAAAAGAG GTTTAATTGG GCTTAGAGTT CCACGTGATT 2700 GGGGAGGCCT CAGAATCACA GTAGGAGGCA AAAGTTATTC TTACATGGTG GCTGCAAGAG 2760 AAGATGAGGA AGAAGCAAAA GAAGAAACCC CTGATAAACC CATCGGATCT CCTGAGGCTT 2820 ATTAACTATC ATGAGAATAG CACAAGAAAG ACCGGCCCCC ATGATTCAAT TACCTCTACC 2880 TGGGTCCCTC CAATAACATG TGGAAATTCT GGTAGATACA ATTCAAGTTG AGATTTGGGT 2940 GGGAACACAG CCAAACCATA TCACTCAGCA AGGCAGATAA CTTTCTCACT GAGCCTATGC 3000 AACAGAAAAC CATCTGGGAT GGTTGTAAGG GGCACAGGAA GTGACTGGTA GGATCACTGC 3060 CAAAGCTGAG CACTCAGGAG AAGGCAATAG AATCCTATTC TCCATAGTAT GCTATAAGAT 3120 ACTGAAGTAC ACTTCTTCAC TATCTCTTTG GACTTAGAAT TAGCACTACA TTCCTTGTTA 3180 TACAGAAAAA TTACTAAGGA AATTCATAGG ATGACAAAAA CTTTCAGAAC TGAAAAACAG 3240 GAAATGTAAG CTTTTTAGTT CTTTGGTATT CGAAGTATGC CTAAAAGACA ATGCAAAATC 3300 CAAGAAAAGA ATGGTGGGGT TTTTGTTTGT TTGGTTTTGT TTTTGTTTTA CAGCTGGAGT 3360 AGAATACAAA GGGATGGAGT TGAAACAAAT GAGAGGAAAT TGGAATTCTA AACTTATTCT 3420 CATTGGCATT AGAAAGGCAC CTACATGTAT TTCACATGAG CCGGTGACTG CTGACTTGCA 3480 TTCTTATTTT TTCCCTATAG ATTAAAAAGG AGGTACAATG GTAGAACTGT AATCCTGTCC 3540 TTTGTCATAA ATTTTCATAT TCATAAAGGT GAGTGTTAGC CCGCTTGTGA AATCTGAAGT 3600 TGAGTAACTT CAAATACTAA CCACAGAGGG AAAGGCAGCA AGAGGAGAGG CATAAATTTA 3660 GGATCTCACC CTTCATTCCA CAGACACACA CAGCCTCTCT GCCCACCTCT GCTTCCTCTA 3720 GGAACACAGG TAAGAGCTTC AAGCCTCTCC AGCTTAATAA CATGAATTAT TTTTGAGAAT 3780 AATAATGATA CTGTGTTCTA TATCATGCAT CTCCTGCATT CTGTCTGATT ATATTTTACT 3840 TATTCTGCCA GAGCAAAATT AAAATACCTA TTTCATCTGA TTTGTCCTTT ATCTAAATTG 3900 CTTAGTTCCA AGTAAACCAA GGCACTTTTA GGAACACAGA GGGAGAGTGC CTTGCAGCCA 3960 GAGAGTCTTG AAGGAGATGT CAGGGACGCA TCTTAACAGC TGGTTGGATG TGATCCACAG 4020 AGGTCTCCTG TTAGCATTCA TTGTAAAGCC ATCCTACCTA GCTCTAGTGT AACCAGCAAT 4080 GAAAGAAAGA TAAAGAGGGT CGATTACTTA TTTACAATAG TCTTTAAAAA CGTAGTTTTG 4140 TAAGCCTTCT AATTAGGACA TTAATATATT TAATATATGC ACATTGTAGA AAGATTGAAG 4200 CGTTAAAAAT AAGAGAAAAA CTTTAAATGT CAAAATCTCA CAACCCAGAT ATATCATTTC 4260 TTTAAGAAAA TTGTACTACA AAATACCATT CCATTTATTA AAGTCATTCT GACAGGAATC 4320 TGATGCTTTT CCAGGAGTTC CAGATCACAT CGAGTTCACC ATGAATTCAC TCAGTGAAGC 4380 CAACACCAAG TTCATGTTCG ATCTGTTCCA ACAGTTCAGA AAATCAAAAG AGAACAACAT 4440 CTTCTATTCC CCTATCAGCA TCACATCAGC ATTAGGGATG GTCCTCTTAG GAGCCAAAGA 4500 CAACACTGCA CAACAAATTA GCAAGGTAGC TATCAGCATC ATTACGTTGT CCTGTTGCAG 4560 TTTTTCTCTG GTTCCGTCGG CTAGCACGCA GATGGTAATA GATGTGGTGG TCTGATGGGT 4620 AGCACAGGGG GCTGTGCAGG AATTCCCATA ACTGTGAGAC CACTGACTTA AACAGATCTT 4680 TTGAGTAAAG TTTTCTTGTC CCGCTTCATG TCTCTTCCAG GTTCTTCACT TTGATCAAGT 4740 CACAGAGAAC ACCACAGAAA AAGCTGCAAC ATATCATGTG AGTCACAGAG CACTCTGATT 4800 CAGCTTTAGA TCCCTGAACA GGTCATAGTT TAAACCTGGA ACTTCACAAA AACTAAGAAA 4860 AGGCCAGTTT TAGGGAAAAT CTTGβACACA AAGATTGAGA CATACAGAGT GGGTTGGCAT 4920 TTCATGGCAC ATAATTATTA TTCCTCATTT CTGCGTTACT AAAAGACAGT CAGCACTGTA 4980 CCTCAGAGCA TAGGTCTGGA TCAGGATAβG CTGGGTTCAG ACTCCAGCTT TGCTCTTCAC 5040 AAATGATGAA TAAGAGCAGG ACACAACTGC TCGGAGTCCC AGTGACCTCA TCCCAGAAAA 5100 CTAAGGGTAA GAAAAAATCT GACTCAATAC ATGCAAATAC ATGCAAATGT TTACAACAGT 5160 GCCTTGCCCA TAAAAGTCAT AATAAATGTT ATTATTATTA TAAAGTAGCT ATAATTATAC 5220 TAATCATAAT AATGTGAAAA TAATTTAATT TTCATTGAGT CATTAATGAG ATTCAGAGGA 5280 ATAAGCACAA GTCCAAGTAT ATTTTGGAAA ATGATTGCTA TGGAATATAT TGGTTTAGAG 5340 CCTTAATAGT GCAAAATGCT TTGCTGGAAG GTAGAAAGTT CTAGATTTAA ACAGGCTTAG 5400 GTTCAAAACT TGGCACTTCT AATTTATGTC TCTATAAACA GGGTTTTTTT CCCCATTCTC 5460 TGAGCTTTCT TGTGTTCATC TGAATTGAAC TAAAGACTTA GAGTTACCCA TGTAAAGTCC 5520 TTAGCCATGG ACCTGGCATA CACTCTTCTT ACGTGCAGAG AATGACCATC ATGAGGAAAG 5580 AGCCACAGAT CAGTCAATGT GTCCTACAAG ATAATAGCAC CAACAGGTAT AACAGGGCTT 5640 CCTGGCATAA TCTATTTAAA ATATCCAACC TTCAACATAC TCGTATCCTT GATGACTGTT 5700 AGAAGTGAAA TATGGTCCTT GCCCATAAGG AGCTGAGAGT TTAACTGGGA AGCTAAACCT 5760 AACCCTTTAA ACCAACAAGG AGAAAATCTA CTGGTAGACA GCGCTGCATC TTTAGTTCAG 5820 AAGAGAAAAG ATTGCAGTAC GTTAGAGCAA GAAGAATTTT CTGGAAGAAG TCAAATATAA 5880 GGTGGATTTT GAAGGGTATT TGAGGTGAAA TACACCAATT ATCAGGGAAT AACATCAAAG 5940 GTCCTCAATG AGACTACCAG CATTTAGGGA CTGATCTAAC AGACTTAGCA TGGGTTTAGT 6000 ATTTACATTG ATACAGCAAT TGAATGATCT CCTTTTTTGA TGTTTGAAGG TTGATAGGTC 6060 AGGAAATGTT CATCACCAGT TTCAAAAGCT TCTGACTGAA TTCAACAAAT CCACTGATGC 6120 ATATGAGCTβ AAGATCGCCA ACAAGCTCTT CGGAGAAAAG ACGTATCAAT TTTTACAGGT 6180 AATTTCACCT GGCCTACCCA CATTTCATTT GCATCCTGAT GTCTGTGTCT CTGAGTGGCC 6240 AAATGGAAGA AAGCAAGGCA GATGAGCCTG GCCGACCCAG GTGGAGAGCA TTTACTCAGA 6300 GTGCATTAGC TCCATTTCCA CAACTCTCCC CCACTGGAGT GTCCCAGACC CCAACGATAC 6360 ATCACTGAAG TGTGGATTTA GGGATAATCT TGTGATAAAA GAGGAGGTTG TGTAATAGAG 6420 TGAGTAAGAG TAATAAGTAA TAAGATACCA TCGATAAACT GGCACTGACT CAGTCACATA 6480 CGATACATCT TGGTGGGAAA TGTATGACTA ATGGGATATT ATTGGAATGG GCAGGCTTGG 6540 GTGAGTTCCT GAGAATAGTT GAGGAAGTAC CAGGAAATAT TGAATGCACA GGATGAAAGA 6600 CAAAAACAAA GATCAGAAAC ATCATGGTTA AAATTACTGG AGAGAAGTCT GAGAAGCAAT 6660 GAATCTCCTT CAGGGAAGCC TGCTCTGCAG TTTGCAAACC ACAGCCTCTT CTGCTTCTGC 6720 CTTTTGCCAA GATGATATTG ACCTTCAGTG ACCTCTTTCT TβTGCCAGCC CACATTCCCC 6780 TTTTGCATTG CCTACATGAC ACCTGTATAA AAATATCCAT GGACAGGAGA TACTGCATCT 6840 ATTCAGGGTC TGGATTCAGC TTACTGTTGT TACAAATAAG TAAGTTTGGT AATATATAGT 6900 TACATAAATT ACTCCTAATT CCTACTTCTT CCTTCATATC TCAAAGGAAT ATTTAGATGC 6960 CATCAAGAAA TTTTACCAGA CCAGTGTGGA ATCTACTGAT TTTGCAAATG CTCCAGAAGA 7020 AAGTCGAAAG AAGATTAACT CCTGGGTGGA AAGTCAAACG AATGGTAGGA GAGCCACCCA 7080 TTATAGAAAC ACCTTTGAGA AACCTATGCC AGTGAGCCTT GTGCTTGACA CTGCATGGGG 7140 GAACAGGTGT GGGGATTGAG ATGGGTTTGC AβGGAGGGCT GAAGAGGGCA CTCCAGATGA 7200 AGGATTTGTC CAAATGAATA TGAAGAGAGC CTAGGGGAGC CAAGGAGGAA ATCACAGGAA 7260 GCCAATTAGA TGGAAACACA TCTGGAGAAT TATTTGCTTA TGGCCCTGCA TGACAATAGC 7320 TTTGTGGATC CCCTGTCTCC GCTCAGACCT ATTTTGAGAT CATATCCTTT ACTTTAAATC 7380 AGACTCAAAT TTTTATGATG AATATTTAAT AGAAAACATT AGAAAGCGTC TCTCGTCTCC 7440 TTTACTAATT GGGAAACAAG CAGCTCTCTG GTAAATCACC CTTTTGTCTC TGAGCTGGAG 7500 CTGCCTGGAT CACATCTGTA GCCAATGTGT TCTGCAGGGA TTATCACAGC TCTCTTCCCC 7560 ATCAAGGGCA AAGAGCTTGA CAAAGTCTCC ATTCTACAGA CATCTTTCTT ACCTCCCACC 7620 TCTCATTACA GGCCAAACTT ACAGCAACTC AACATGAGAG TGAATAGGAA GATACCCCCG 7680 GAAGTAGTGT CTGACAGCAC AGGACATGCG TTTCATATTA CAGAGCTCAA GTCACTCATC 7740 CTAAAATGCA ATCAGGGCCT CCTTCCTCTG AATGGGGACC CCGTAGTTAA AAAAAAATAA 7800 AAGTAGGAAG AGGAGGGAGG GAGAAAGGAA AGACACATGT TGGAAGAGTA GACAAAATCA 7860 GTTTATCAGT ATTCCAAATC AGATGATTGG AGACATTCAT ACACAGAGAA CGTGAACTCC 920 TTCTCTATCA CAAGAAGTGA TGTCTCCATC AAGGGTAACT TTATACGACT GGAGCCTTGA 7980 AGAAAGCTGC ATCTGGTGAA CCACTGGTCA GTGAGTCTAA CAATTCAAAG ATCAAAGTCA 8040 GTGAGTCTCA AGCAGGGATT TGGGTCAATA ATTAACGATC AGTCACGAAC ATTTGCAAAG 8100 CATCTTCCAG ACAAGCCATT TGTAGCTTGT GTAAAAGACT CTTTTATTCT TTCCCTTGCA 8160 GAAAAAATTA AAAACCTATT TCCTGATGGG ACTATTGGCA ATGATACGAC ACTGGTTCTT 8220 GTGAACGCAA TCTATTTCAA AGGGCAGTGG GAGAATAAAT TTAAAAAAGA AAACACTAAA 8280 GAGGAAAAAT TTTGGCCAAA CAAGGTATTG TCTATATTTT ATTTATATAG TGTAATATGT 8340 TAATACATGG AATGTTAAAC ATTTCTGATG GAATGTAACA TGATAAGTAA AAAATAAAAA 8400 TTGTTCATGT CTGTTATTTT GTTGTTTTAC TCTTATAACT TTATTTAGTT AGGAATACCT 8460 GAAAAACTAT TGTTTCTAAC TCATGGAATT CCTGGGTTAT TTCTTAGAAG AAGAAGGATG 8520 TGTTGCTATC TCAATAATAT TATCTTTTTT GTCTTGTGTT TCACGTGTTA TTTGTTGGAC 8580 ACATTGATTT ATTGCAGAAT ACATACAAAT CTGTACAGAT GATGAGGCAA TACAATTCCT 8640 TTAATTTTGC CTTGCTGGAG GATGTACAGG CCAAGGTCCT GGAAATACCA TACAAAGGCA 8700 AAGATCTAAG CATGATTGTG CTGCTGCCAA ATGAAATCGA TGGTCTGCAG AAGGTAAGAA 8760 CTTGCATCTA CAACTCTTCC TTCTACTGCC GGACATTTTT CCAAAGATAC CAAGTTTAAA 8820 CAAGGTAAAA GCTTATGACC GAGTTGCCTC AAAATGATGA AAAATTCTAA ATGAGGAATG 8880 ATGACTCACC TTCATATTAC AAATATTTGA GCATAGGGCC TGACACAAAC TGAAAGCTTA 8940 GTTTTTGTTT GTTTGTTTGT TTTTATTATT ATTATTATAA TACTTTAAGC TTTAGGGTAC 9000 ATGTGCACAA TGTGCAGGTT AGTTACATAT GTATACATGT GCCATGCTGG TGTGCTGCAC 9060 CCATTAACTC ATCATTTAGC GTTAGGTATA TCTCCTAATG CTATCCCTCC CCCCTCCCCC 9120 CACCCCACAA CAGTCCTCAG AGTGTGATGT TACCTTCCTG TGTCCAAGTG TTCTCATTGT 9180 TCAATTCCCA TCTATGATTT AATTCCATCT ATGGCTTAGT TAATGATTAA TTTATTAGAG 9240 TTACATGCAT TGGATATCAA TTTGATGATA TTATTATGCA GCAATTTAAA CTTGACTGGG 9300 AGAAATATAT ACCAATGTGA GGAAAGTTTA CAAATAGGCC GAGTAGAAAA GGGAATACAA 9360 ATTTAGGAAT TTAGGGAATT ACAATTTAAT AATTGCAATG TGTACTAAAT AATGTATACA 9420 GAAAAATATG ATGAGCCTAT TAAAAATTGA CACATGTAGT AGGCTGTTGG CACAAGAAAT 9480 AGTGATACAT ACAGTTCATT GTGTACAAAA TAATGTAATC ATATTTTACA TGTGTATCAT 9540 ACAGTTGTAT ACATACATAT GTACACATAT ACATATACGT AAAAACATGA TTCTGTTTTT 9600 ACATACATGT ATATACATAT ACACATATAA CCCAATGTAT TTATATATTC AGGACTCATA 9660 TTTTACCTAT TAGAATAATA ATGTCTATTA AAGTGAACCT TCTGTATTTC ACATTTATTG 9720 CCAAAATAAC GAATCTCCAC ATAGTCAATT CATTGTTAAG GTGTATTAGA GATCGACAGT 9780 TAGTCATATC AGTTTCTTTT TTCCATTTGT ATAGCTTGAA GAGAAACTCA CTGCTGAGAA 9840 ATTGATGGAA TGGACAAGTT TGCAGAATAT GAGAGAGACA TGTGTCGATT TACACTTACC 9900 TCGGTTCAAA ATGGAAGAGA GCTATGACCT CAAGGACACG TTGAGAACCA TGGGAATGGT 9960 GAATATCTTC AATGGGGATG CAGACCTCTC AGGCATGACC TGGAGCCACG GTCTCTCAGT 10020 ATCTAAAGTC CTACACAAGG CCTTTGTGGA GGTCACTGAG GAGGGAGTGG AAGCTGCAGC 10080 TGCCACCGCT GTAGTAGTAG TCGAATTATC ATCTCCTTCA ACTAATGAAG AGTTCTGTTG 10140 TAATCACCCT TTCCTATTCT TCATAAGGCA AAATAAGACC AACAGCATCC TCTTCTATGG 10200 CAGATTCTCA TCCCCATAGA TGCAATTAGT CTGTCACTCC ATTTAGAAAA TGTTCACCTA 10260 GAGGTGTTCT GGTAAACTGA TTGCTGGCAA CAACAGATTC TCTTGGCTCA TATTTCTTTT 10320 CTATCTCATC TTGATGATGA TAGTCATCAT CAAGAATTTA ATGATTAAAA TAGCATGCCT 10380 TTCTCTGTTT CTCTTAATAA GCCCACATAT AAATGTACTT TTCCTTCCAG AAAAATTTCC 10440 CTTGAGGAAA AATGTCCAAG ATAAGATGAA TCATTTAATA CCGTGTCTTC TAAATTTGAA 10500 ATATAATTCT GTTTCTGACC TGTTTTAAAT GAACCAAACC AAATCATACT TTCTCTTCAA 10560 ATTTAGCAAC CTAGAAACAC ACATTTCTTT GAATTTAGGT GATACCTAAA TCCTTCTTAT 10620 GTTTCTAAAT TTTGTGATTC TATAAAACAC ATCATCAATA AAATAATGAC ATAAAATCAT 10680 TTTTGCTTTA CCTGTTTTCT CTCTGGAAAG GGCAAGTGTC CAGTTACACA TAGGAAAGAT 10740 AATTTAGAGA TATATTAATC ATATATAAAG GAAAATTAAA AACAGAGTAG TTCATGATGA 10800 GCCTGGAGTA GAAGGCATAT CCCAGAACAG GAGGAGCCTT GTAAACCACA TAGGAACTTC 10860 CTATTTTATG CTAAAGGGAT AAGAAACTCA TTACAGGCTT TGATGGTTGT TTGTCAAAGA 10920 GGGGCATAAA ATTATCATAT CCACATCTAG AAAATACATC TCTGGCTACG CTGATATCAA 10980 TGGATGCGAG GAAAGAACAG TGTGGTTACC ATATATAAAT TAGGAAATCA TTAGAGTATT 11040 GGGAGTGGAA ATGGAGAGAA AGAAAGAGCC TGGGGGAATT ATTTAGGAAA TAATAGTTAC 11100 AGAAAGACAT CTAAGTTGCT GACCTATCTG ACTGGATGGA TGGAAGAATA TCTTGTTTCT 11160 GAGAGAAAAA AAGACTTTGG GTTTAAATTT GTACTTGATG AATTAAGGTA CTTTTAATAT 11220 TCAAATGGAT TTGCCTGGCA GGCACTTGAA GATATTAGTC TAAATCTCAG AAACAGAATA 11280 TGATCTGAAG CTCTAAATTT GTGATATTCA ATATAAATAC TTTAGAGTCA TTGGGATAAA 11340 TATGGTAGTT GTAGCTAAAA GCAAAAATAA GATACTAGGG AGAAAGGATA AAGTTAGAAG 11400 AAAGAAGAAT CTAGAATTGA CCTTGAAGTA TATCAGCATG TGTAAAGATC AGGAATTGAT 11460 CATTTTTATT TTCCAGAAAG TAGCTTTTCT TAGGGTTCCA TATTTACTCC CATAGATTCT 11520 TCCC
Seq ID NO: 177 Protein sequence Protein Accession ft: BAB21525.1
1 11 21 31 41 51
I I I I I I
MNSLSEANTK FMFDLFQQFR KSKENNIFYS PISITSALGM VLLGAKDNTA QQISKVLHFD 60
QVTENTTEKA ATYHVDRSGN VHHQFQKLLT EFNKSTDAYE LKIANKLFGE KTYQFLQEYL 120 DAIKKFYQTS VESTDFANAP EESRKKINSW VESQTNEKIK NLFPDGTIGN DTTLVLVNAI 180 YFKGQWENKF KKENTKEEKF WPNKNTYKΞV QMMRQYNSFN FALLEDVQAK VLEIPYKGKD 240 LSMIVLLPNE IDGLQKLEEK LTAEKLMEWT SLQNMRETCV DLHLPRFKME ESYDLKDTLR 300 TMGMVNIFNG DADLSGMTWS HGLSVSKVLH KAFVEVTEEG VEAAAATAW WELSSPSTN 360 EEFCCNHPFL FFIRQNKTNS ILFYGRFSSP
Seq ID NO : 178 DNA sequence
Nucleic Acid Accession # : NM_001910 .1
Coding sequence : 50 . . 1240
11 21 31 41 51
GGAGAGAAGA AAGGAGGGGG CAAGGGAGAA GCTGCTGGTC GGACTCACAA TGAAAACGCT 60 CCTTCTTTTG CTGCTGGTGC TCCTGGAGCT GGGAGAGGCC CAAGGATCCC TTCACAGGGT 120 GCCCCTCAGG AGGCATCCGT CCCTCAAGAA GAAGCTGCGG GCACGGAGCC AGCTCTCTGA 180 GTTCTGGAAA TCCCATAATT TGGACATGAT CCAGTTCACC GAGTCCTGCT CAATGGACCA 240' GAGTGCCAAG GAACCCCTCA TCAACTACTT GGATATGGAA TACTTCGGCA CTATCTCCAT 300 TGGCTCCCCA CCACAGAACT TCACTGTCAT CTTCGACACT GGCTCCTCCA ACCTCTGGGT 360 CCCCTCTGTG TACTGCACTA GCCCAGCCTG CAAGACGCAC AGCAGGTTCC AGCCTTCCCA 420 GTCCAGCACA TACAGCCAGC CAGGTCAATC TTTCTCCATT CAGTATGGAA CCGGGAGCTT 480 GTCCGGGATC ATTGGAGCCG ACCAAGTCTC TGTGGAAGGA CTAACCGTGG TTGGCCAGCA 540 GTTTGGAGAA AGTGTCACAG AGCCAGGCCA GACCTTTGTG GATGCAGAGT TTGATGGAAT 600 TCTGGGCCTG GGATACCCCT CCTTGGCTGT GGGAGGAGTG ACTCCAGTAT TTGACAACAT 660 GATGGCTCAG AACCTGGTGG ACTTGCCGAT GTTTTCTGTC TACATGAGCA GTAACCCAGA 720 AGGTGGTGCG GGGAGCGAGC TGATTTTTGG AGGCTACGAC CACTCCCATT TCTCTGGGAG 780 CCTGAATTGG GTCCCAGTCA CCAAGCAAGC TTACTGGCAG ATTGCACTGG ATAACATCCA 840 GGTGGGAGGC ACTGTTATGT TCTGCTCCGA GGGCTGCCAG GCCATTGTGG ACACAGGGAC 900 TTCCCTCATC ACTGGCCCTT CCGACAAGAT TAAGCAGCTβ CAAAACGCCA TTGGGGCAGC 960 CCCCGTGGAT GGAGAATATG CTGTGGAGTG TGCCAACCTT AACGTCATGC CGGATGTCAC 1020 CTTCACCATT AACGGAGTCC CCTATACCCT CAGCCCAACT GCCTACACCC TACTGGACTT 1080 CGTGGATGGA ATGCAGTTCT GCAGCAGTGG CTTTCAAGGA CTTGACATCC ACCCTCCAGC 1140 TGGGCCCCTC TGGATCCTGG GGGATGTCTT CATTCGACAG TTTTACTCAG TCTTTGACCG 1200 TGGGAATAAC CGTGTGGGAC TGGCCCCAGC AGTCCCCTAA GGAGGGGCCT TGTGTCTGTG 1260 CCTGCCTGTC TGACAGACCT TGAATATGTT AGGCTGGGGC ATTCTTTACA CCTACAAAAA 1320 GTTATTTTCC AGAGAATGTA GCTGTTTCCA GGGTTGCAAC TTGAATTAAG ACCAAACAGA 1380 ACATGAGAAT ACACACACAC ACACACATAT ACACACACAC ACACTTCACA CATACACACC 1440 ACTCCCACCA CCGTCATGAT GGAGGAATTA CGTTATACAT TCATATTTTG TATTGATTTT 1500 TGATTATGAA AATCAAAAAT TTTCACATTT GATTATGAAA ATCTCCAAAC ATATGCACAA 1560 GCAGAGATCA TGGTATAATA AATCCCTTTG CAACTCCACT CAGCCCTGAC AACCCATCCA 1620 CACACGGCCA GGCCTGTTTA TCTACACTGC TGCCCACTCC TCTCTCCAGC TCCACATGCT 1680 GTACCTGGAT CATTCTGAAG CAAATTCCGA GCATTACATC ATTTTGTCCA TAAATATTTC 1740 TAACATCCTT AAATATACAA TCGGAATTCA AGCATCTCCC ATTGTCCCAC AAATGTTTGG 1800 CTGTTTTTGT AGTTGGATTG TTTGTATTAG GATTCAAGCA AGGCCCATAT ATTGCATTTA 1860 TTTGAAATGT CTGTAAGTCT CTTTCCATCT ACAGAGTTTA GCACATTTGA ACGTTGCTGG 1920 TTGAAATCCC GAGGTGTCAT TTGACATGGT TCTCTGAACT TATCTTTCCT ATAAAATGGT 1980 AGTTAGATCT GGAGGTCTGA TTTTGTGGCA AAAATACTTC CTAGGTGGTG CTGGGTACTT 2040 CTTGTTGCAT CCTGTCAGGA GGCAGATAAT GCTGGTGCCT CTCTATTGGT AATGTTAAGA 2100 CTGCTGGGTG GGTTTGGAGT TCTTGGCTTT AATCATTCAT TACAAAGTTC AGCATTTT
Seq ID NO: 179 Protein sequence Protein Accesεion ft: NP 001901.1
11 21 31 41 51
I I I I I
MKTLLLLLLV LLELGEAQGS LHRVPLRRHP SLKKKLRARS QLSEFWKSHN LDMIQFTESC 60 SMDQSAKEPL INYLDMEYFG TISIGSPPQN FTVIFDTGSS NLWVPSVYCT SPACKTHSRF 120 QPSQSSTYSQ PGQSFSIQYG TGSLSGIIGA DQVSVEGLTV VGQQFGESVT EPGQTFVDAE 180 FDGILGLGYP SLAVGGVTPV FDNMMAQNLV DLPMFSVYMS SNPEGGAGSE LIFGGYDHSH 240 FSGSLNWVPV TKQAYWQIAL DNIQVGGTVM FCSEGCQAIV DTGTSLITGP SDKIKQLQNA 300 IGAAPVDGEY AVECANLNVM PDVTFTINGV PYTLSPTAYT LLDFVDGMQF CSSGFQGLDI 360 HPPAGPLWIL GDVFIRQFYS VFDRGNNRVG LAPAVP
Seq ID NO: 180 DNA sequence
Nucleic Acid Accesεion ft: NM_018058.1
Coding sequence: 319..1575
1 11 21 31 41 51
I I I I I I
TACGCGCTGC GGGACCGGCA GGGGAACGCC ATCGGGGTCA CAGCCTGCGA CATCGACGGG 60 GACGGCCGGG AGGAGATCTA CTTCCTCAAC ACCAATAATG CCTTCTCGGG GGTGGCCACG 120 TACACCGACA AGTTGTTCAA GTTCCGCAAT AACCGGTGGG AAGACATCCT GAGCGATGAG 180 GTCAACGTGG CCCGTGGTGT GGCCAGCCTC TTTGCCGGAC GCTCTGTGGC CTGTGTGGAC 240 AGAAAGGGCT CTGGACGCTA CTCTATCTAC ATTGCCAATT ACGCCTACGG TAATGTGGGC 300 CCTGATGCCC TCATTGAAAT GGACCCTGAG GCCAGTGACC TCTCCCGGGG CATTCTGGCG 360 CTCAGAGATG TGGCTGCTGA GGCTGGGGTC AGCAAATATA CAGGGGGCCG AGGCGTCAGC 420 GTGGGCCCCA TCCTCAGCAG CAGTGCCTCG GATATCTTCT GCGACAATGA GAATGGGCCT 480 AACTTCCTTT TCCACAACCG GGGCGATGGC ACCTTTGTGG ACGCTGCGGC CAGTGCTGGT 540 GTGGACGACC CCCACCAGCA TGGGCGAGGT GTCGCCCTGG CTGACTTCAA CCGTGATGGC 600 AAAGTGGACA TCGTCTATGG CAACTGGAAT GGCCGCCACC GCCTCTATCT GCAAATGAGC 660 ACCCATGGGA AGGTCCGCTT CCGGGACATC GCCTCACCCA AGTTCTCCAT GCCCTCCCCT 720 GTCCGCACGG TCATCACCGC CGACTTTGAC AATGACCAGG AGCTGGAGAT CTTCTTCAAC 780 AACATTGCCT ACCGCAGCTC CTCAGCCAAC CGCCTCTTCC GCGTCATCCG TAGAGAGCAC 840 GGAGACCCCC TCATCGAGGA GCTCAATCCC GGCGACGCCT TGGAGCCTGA GGGCCGGGGC 900 ACAGGGGGTG TGGTGACCGA CTTCGACGGA GACGGGATGC TGGACCTCAT CTTGTCCCAT 960 GGAGAGTCCA TGGCTCAGCC GCTGTCCGTC TTCCGGGGCA ATCAGGGCTT CAACAACAAC 1020 TGGCTGCGAG TGGTGCCACG CACCCGGGTT GGGGCCTTTG CCAGGGGAGC TAAGGTCGTG 1080 CTCTACACCA AGAAGAGTGG GGCCCACCTG AGGATCATCG ACGGGGGCTC AGGCTACCTG 1140 TGTGAGATGG AGCCCGTGGC ACACTTTGGC CTGGGGAAGG ATGAAGCCAG CAGTGTGGAG 1200 GTGACGTGGC CAGATGGCAA GATGGTGAGC CGGAACGTGG CCAGCGGGGA GATGAACTCA 1260 GTGCTGGAGA TCCTCTACCC CCGGGATGAG GACACACTTC AGGACCCAGC CCCACTGGAG 1320 ACACCAATGA ATGCATCCAG TTCCCATTCG TGTGCCCTCG AGACAAGCCC GTATGTGTCA 1380 ACACCTATGG AAGCTACAGG TGCCGGACCA ACAAGAAGTG CAGTCGGGGC TACGAGCCCA 1440 ACGAGGATGG CACAGCCTGC GTGGGGACTC TCGGCCAGTC ACCGGGCCCC CGCCCCACCA 1500 CCCCCACCGC TGCTGCTGCC ACTGCCGCTG CTGCTGCCGC TGCTGGAGCT GCCACTGCTG 1560 CACCGGTCCT CGTAGATGGA GATCTCAATC TGGGGTCGGT GGTTAAGGAG AGCTGCGAGC 1620 CCAGCTGCTG AGCAGGGGTG GGACATGAAC CAGCGGATGG AGTCCAGCAG GGGAGTGGGA 1680 AAGTGGGCTT GTGCTGCTGC CTAGACAGTA GGGATGTAAA GGCCTGGGAG CTAGACCCTC 1740 CCCAAGCCCA TCCATGCACA TTACTTAGCT AACAATTAGG GAGACTCGTA AGGCCAGGCC 1800 CTGTGCTGGG CACATAGCTG TGATCACAGC AGACAGGGTC GCTGCCCTGA TGGCGCTTAC 1860 ATTCCAGTGG GTCTAATGAC CATATCTTAG GACACAGATG TGCCCAGGGA GGTGGTGTCA 1920 CTGCACAGGA AGTATGAGGA CTTTAGTGTC CTGAGTTCAA ATCCTGATTC AGGAACTCAC 1980 AAAGCTATGT GACCTTACAC CAGTCACTTA ACTTGTTAGC CATCCATTAT CGCATCTGCA 2040 AAATGGGGAT TAAGAATAGA ATCTTGGGGT TAGTGTGGAG ATTAGATTAA ATGTATGTAA 2100 GACACTTGGC ACAAAACCTG GCACATAGTA AAGGCTCAAT AAAAACAAGT GCCTCTCACT 2160 GGGCTTTGTC AACACGTG
Seq ID NO: 181 Protein sequence Protein Accession ft: NP 060528.1
11 21 31 41 51
MDPEASDLSR GILALRDVAA EAGVSKYTGG RGVSVGPILS SSASDIFCDN ENGPNFLFHN 60 RGDGTFVDAA ASAGVDDPHQ HGRGVALADF NRDGKVDIVY GNWNGPHRLY LQMSTHGKVR 120 FRDIASPKFS MPSPVRTVIT ADFDNDQELE IFFNNIAYRS SSANRLFRVI RREHGDPLIE 180 ELNPGDALEP EGRGTGGWT DFDGDGMLDL ILSHGESMAQ PLSVFRGNQG FNNNWLRWP 240 RTRVGAFARG AKWLYTKKS GAHLRIIDGG SGYLCEMEPV AHFGLGKDEA SSVEVTWPDG 300 KMVSRNVASG EMNSVLEILY PRDEDTLQDP APLETPMNAS SSHSCALETS PYVSTPMEAT 360 GAGPTRSAVG ATSPTRMAQP AWGLSASHRA PAPPPPPLLL PLPLLLPLLE LPLLHRSS
Seq ID NO: 182 DNA sequence Nucleic Acid Accession it: AJ279016 Coding sequence: 1..1962
11 21 31 41 51
I I I I
ATGTCCAGGA TGTTACCGTT C 1CTGCTGCTG CTCTGGTTTC TGCCCATCAC TGAGGGGTCC 60
CAGCGGGCTG AACCCATGTT CACTGCAGTC ACCAACTCAG TTCTGCCTCC TGACTATGAC 120
AGTAATCCCA CCCAGCTCAA CTATGGTGTG GCAGTTACTG ATGTGGACCA TGATGGGGAC 180
TTTGAGATCG TCGTGGCGGG GTACAATGGA CCCAACCTGG TTCTGAAGTA TGACCGGGCC 240
CAGAAGCGGC TGGTGAACAT CGCGGTCGAT GAGCGCAGCT CACCCTACTA CGCGCTGCGG 300
GACCGGCAGG GGAACGCCAT CGGGGTCACA GCCTGCGACA TCGACGGGGA CGGCCGGGAG 360
GAGATCTACT TCCTCAACAC CAATAATGCC TTCTCGGGGG TGGCCACGTA CACCGACAAG 420
TTGTTCAAGT TCCGCAATAA CCGGTGGGAA GACATCCTGA GCGATGAGGT CAACGTGGCC 480
CGTGGTGTGG CCAGCCTCTT TGCCGGACGC TCTGTGGCCT GTGTGGACAG AAAGGGCTCT 540
GGACGCTACT CTATCTACAT TGCCAATTAC GCCTACGGTA ATGTGGGCCC TGATGCCCTC 600
ATTGAAATGG ACCCTGAGGC CAGTGACCTC TCCCGGGGCA TTCTGGCGCT CAGAGATGTG 660
GCTGCTGAGG CTGGGGTCAG CAAATATACA GGGGGCCGAG GCGTCAGCGT GGGCCCCATC 720
CTCAGCAGCA GTGCCTCGGA TATCTTCTGC GACAATGAGA ATGGGCCTAA CTTCCTTTTC 780
CACAACCGGG GCGATGGCAC CTTTGTGGAC GCTGCGGCCA GTGCTGGTGT GGACGACCCC 840
CACCAGCATG GGCGAGGTGT CGCCCTGGCT GACTTCAACC GTGATGGCAA AGTGGACATC 900
GTCTATGGCA ACTGGAATGG CCCCCACCGC CTCTATCTGC AAATGAGCAC CCATGGGAAG 960
GTCCGCTTCC GGGACATCGC CTCACCCAAG TTCTCCATGC CCTCCCCTGT CCGCACGGTC 1020
ATCACCGCCG ACTTTGACAA TGACCAGGAG CTGGAGATCT TCTTCAACAA CATTGCCTAC 1080
CGCAGCTCCT CAGCCAACCG CCTCTTCCGC GTCATCCGTA GAGAGCACGG AGACCCCCTC 1140
ATCGAGGAGC TCAATCCCGG CGACGCCTTG GAGCCTGAGG GCCGGGGCAC AGGGGGTGTG 1200
GTGACCGACT TCGACGGAGA CGGGATGCTG GACCTCATCT TGTCCCATGG AGAGTCCATG 1260
GCTCAGCCGC TGTCCGTCTT CCGGGGCAAT CAGGGCTTCA ACAACAACTG GCTGCGAGTG 1320
GTGCCACGCA CCCGGTTTGG GGCCTTTGCC AGGGGAGCTA AGGTCGTGCT CTACACCAAG 1380
AAGAGTGGGG CCCACCTGAG GATCATCGAC GGGGGCTCAG GCTACCTGTG TGAGATGGAG 1440
CCCGTGGCAC ACTTTGGCCT GGGGAAGGAT GAAGCCAGCA GTGTGGAGGT GACGTGGCCA 1500
GATGGCAAGA TGGTGAGCCG GAACGTGGCC AGCGGGGAGA TGAACTCAGT GCTGGAGATC 1560
CTCTACCCCC GGGATGAGGA CACACTTCAG GACCCAGCCC CACTGGAGTG TGGCCAAGGA 1620
TTCTCCCAGC AGGAAAATGG CCATTGCATG GACACCAATG AATGCATCCA GTTGCCATTC 1680
GTGTGCCCTC GAGACAAGCC CGTATGTGTC AACACCTATG GAAGCTACAG GTGCCGGACC 1740
AACAAGAAGT GCAGTCGGGG CTACGAGCCC AACGAGGATG GCACAGCCTG CGTGGGGACT 1800
CTCGGCCAGT CACCGGGCCC CCGCCCCACC ACCCCCACCG CTGCTGCTGC CACTGCCGCT 1860
GCTGCTGCCG CTGCTGGAGC TGCCACTGCT GCACCGGTCC TCGTAGATGG AGATCTCAAT 1920
CTGGGGTCGG TGGTTAAGGA GAGCTGCGAG CCCAGCTGCT GAGCAGGGGT GGGACATGAA 1980
CCAGCGGATG GAGTCCAGCA GGGGAGTGGG AAAGTGGGCT TGTGCTGCTG CCTAGACAGT 2040
AGGGATGTAA AGGCCTGGGA GCTAGACCCT CCCCAAGCCC ATCCATGCAC ATTACTTAGC 2100
TAACAATTAG GGAGACTCGT AAGGCCAGGC CCTGTGCTGG GCACATAGCT GTGATCACAG 2160
CAGACAGGGT CGCTGCCCTG ATGGCGCTTA CATTCCAGTG GGTCTAATGA CCATATCTTA 2220
GGACACAGAT GTGCCCAGGG AGGTGGTGTC ACTGCACAGG AAGTATGAGG ACTTTAGTGT 2280
CCTGAGTTCA AATCCTGATT CAGGAACTCA CAAAGCTATG TGACCTTACA CCAGTCACTT 2340
AACTTGTTAG CCATCCATTA TCGCATCTGC AAAATGGGGA TTAAGAATAG AATCTTGGGG 2400
TTAGTGTGGA GATTAGATTA AATGTATGTA AGACACTTGG CACAAAACCT GGCACATAGT 2460
AAAGGCTCAA TAAAAACAAG TGCCTCTCAC TGGGCTTTGT CAACACG Seq ID NO: 183 Protein sequence Protein Accession ft: CAC08451
11 21 31 41 51
MSRMLPFLLL LWFLPITEGS QRAEPMFTAV TNSVLPPDYD SNPTQLNYGV AVTDVDHDGD 60 FEIWAGYNG PNLVLKYDRA QKRLVNIAVD ERSSPYYALR DRQGNAIGVT ACDIDGDGRE 120 EIYFLNTNNA FSGVATYTDK LFKFRNNRWE DILSDEVNVA RGVASLFAGR SVACVDRKGS 180 GRYSIYIANY AYGNVGPDAL IEMDPEASDL SRGILALRDV AAEAGVSKYT GGRGVSVGPI 240 LSSSASDIFC DNENGPNFLF HNRGDGTFVD AAASAGVDDP HQHGRGVALA DFNRDGKVDI 300 VYGNWNGPHR LYLQMSTHGK VRFRDIASPK FSMPSPVRTV ITADFDNDQE LEIFFNNIAY 360 RSSSANRLFR VIRREHGDPL IEELNPGDAL EPEGRGTGGV VTDFDGDGML DLILSHGESM 420 AQPLSVFRGN QGFNNNWLRV VPRTRFGAFA RGAKWLYTK KSGAHLRIID GGSGYLCEME 480 PVAHFGLGKD EASSVEVTWP DGKMVSRNVA SGEMNSVLEI LYPRDEDTLQ DPAPLECGQG 540 FSQQENGHCM DTNECIQFPF VCPRDKPVCV NTYGSYRCRT NKKCSRGYEP NEDGTACVGT 600 LGQSPGPRPT TPTAAAATAA AAAAAGAATA APVLVDGDLN LGSWKESCE PSC
Seq ID NO: 184 DNA sequence Nucleic Acid Accession ft: FGENESHH Coding sequence: 1..4794
11 21 31 41 51
I I I I I I
ATGGCGTGTC CGGGAGGACT CCCAGCCCGT TGCTCTGGTT GGATGGGACT GGGTGGGCCC 60
AGCGGCTCCT CCCCAGCATC CCCTCCCCAT TCCTCCTCCA GGTACAATGG ACCCAACCTG 120
GTTCTGAAGT ATGACCGGGC CCAGAAGCGG CTGGTGAACA TCGCGGTCGA TGAGCGCAGC 180
TCACCCTACT ACGCGCTGCG GGACCGGCAG GGGAACGCCA TCGGGGTCAC AGCCTGCGAC 240
ATCGACGGGG ACGGCCGGGA GGAGATCTAC TTCCTCAACA CCAATAATGC CTTCTCGGGC 300
CACAGCAGCT CAGCGCAGGT CCCTTCTGGG CTCCACAGAA ACAGGCCTGT GCTGAAGCCT 360
CCACCTACAA CCCCTGCAGG CCTCCTGGGT CTGCCTCCAC TCAGCGGAAG GGACTTTTCC 420
TCCTCCCTGG GTCAGGCTTC TCCGGACAGC AGGCAGGGAG AGAGGGTGCC GGTTCCCTGC 480
TGTCGGGGTG GACTGAGACC TACCCATGAA CCAGAACCAT TTCTTCTGAG ACCCAAATCA 540
GGGGTGGCCA CGTACACCGA CAAGTTGTTC AAGTTCCGCA ATAACCGGTG GGAAGACATC 600
CTGAGCGATG AGGTCAACGT GGCCCGTGGT GTGGCCAGCC TCTTTGCCGG ACGCTCTGTG 660
GCCTGTGTGG ACAGAAAGGG CTCTGGACGC TACTCTATCT ACATTGCCAA TTACGCCTAC 720
GGTAATGTGG GCCCTGATGC CCTCATTGAA ATGGACCCTG AGGCCAGTGA CCTCTCCCGG 780
GGCATTCTGG CGCTCAGAGA TGTGGCTGCT GAGGCTGGGG TCAGCAAATA TACAGAAGGC 840
TTCTCCCACA CTGCCTCTCC AAGCATTGGT GAGATATCTG GCAGAACCGA GGAGCGGGAA 900
GGAGGAGACC CAGAGGAGGC AGATGAGGAG CACAGTGGGG ATGGAAGCAC CAGCCAACTG 960
TGCCGGCTGG GCTGGAAGGA CGGGCAGTTC AAGGAAGAAG CAGCAGCTTT GGTGGAGGAA 1020
CAGAGGGAGG CTGGGGCAGC TGGCGTGCCC AGAGGACGTG TTCGAACAGC TCTGCAGACT 1080
TCCAAAAGCC ATTTGGCTGA CAAGAACCTA TTTGGCCCAC CATGTTACTA TTCTGTCTGC 1140
GCGCCTTCTC CAGCCCACCC TTTCCCTGCC CGCCAAGCCC CCCAACACTA CCCTGTAGCC 1200
CCCCTTGTCA CTCAGCTAAT GACACATGGA CGTCTGGCTG GAAAACTAGC CCGGAGTGTC 1260
CCCCACCCCC GAGCCCCAGG AATGGACCCC AAATGTAAGG GCCGCCATGC TGAGCCCGGC 1320
CTGATGGCTG AGGCTTTGGG CGCGTGGCCA GCGCTCAGCA CCACTGTGGT GCCAGGGGGC 1380
CTGAGAAGCT GGGAGGAAAG CAGGCAGAAG GGGCAGGCCA TGTCCAGATG TGCACTCAGG 1440
GAGCTGGGAG GTCCCTGGAG CCAAGCCACA CAGCACCTGC CTGCTAGAGA GCTGTATGAC 1500
CTGGGAGAAC CTCCCATTTT ACAAAGAACA GACGGAGATC CAGGGAGGAG AAGGGACTCG 1560
CCCAAGGTCA CACAGGAGTG CCATCTAGTG GCCACCATGC CAGCTCTCGG GGGACTCGAG 1620
GGCCCCGGGA GGGTGGCCAA GCGAGAGATT GGGAGAGAGA CTGGGGCAGT AGGAAGACCA 1680
CTCTCCCATC CCCTGGTCCC CAACTTCCCC AGCTGCTTGA GGCCTCTTGA AGCCGGGACA 1740
GTGCCGGGAG CTGCCCTGCC TGGGAATCCT GGGAACTGGG TTCTGGACAT GGCCAAGGCC 1800
CTGGCGTGGA ACCAGATGGA AAAAGAGGAG GGGAAGATTC ATGGAGACCA TGAGCCCAGA 1860
TTTAGGCTCA GGAAAGCACG GGAAGCAGAA TTCCCCCCAG GCTCCTCTGA GGAGCCTCTG 1920
CTGCAGTTCC CCTCAGGCCT CAGAGGCAGC CCTGTCCTCC AGGTGGGCCT GGGGCTTGCT 1980
TCTGCCACTC ACTGTGGGTC GATGTCTTTT CTAGGGGGCC GAGGCGTCAG CGTGGGCCCC 2040
ATCCTCAGCA GCAGTGCCTC GGATATCTTC TGCGACAATG AGAATGGGCC TAACTTCCTT 2100
TTCCACAACC GGGGCGATGG CACCTTTGTG GACGCTGCGG CCAGTGCTGA ACGTCGTTTA 2160
GCCTTCATCG TTCACCTCAA ATATCACCTC TGCAGAGATT TTCCTCACTC CCTGTGCCAC 2220
CTAGCAGAAA CTGGTCCTTC CTCCTCCTGC TGCCCGTGGC ATGCACGTCT TCTTCAGGCT 2280
CCACATTGCC ATCATGGTTT GTCTATGAGC TTTACAAGGA CCGGGTCACG GTTCTATTCA 2340
TTCTTGACGC AAGGCTTGGC CTCCAGTGCC CACCGGAGGA CACTCAGCCT CCAGGGTTCT 2400
CAGGGGGCCC CACCCTGCCT TCTGGCAAGA GCTCCCTGTG TCCTGGGGTC TCTGATCCCC 2460
ACTGCCTATT ACATTGTCCT GTGGTCTGCC ATCCCAGAGA GCCTGATGAC CCACAGCTAT 2520
TTGTCCTCTG AAAGAGTCAA CGTGGGTGTG GACGACCCCC ACCAGCATGG GCGAGGTGTC 2580
GCCCTGGCTG ACTTCAACCG TGATGGCAAA GTGGACATCG TCTATGGCAA CTGGAATGGC 2640
CCCCACCGCC TCTATCTGCA AATGAGCACC CATGGGAAGG TCCGCTTCCG GGACATCGCC 2700
TCACCCAAGT TCTCCATGCC CTCCCCTGTC CGCACGGTCA TCACCGCCGA CTTTGACAAT 2760
GACCAGGAGC TGGAGATCTT CTTCAACAAC ATTGCCTACC GCAGCTCCTC AGCCAACCGC 2820
CTCTTCCGAT GCTCCATCCT GGCTCGTGGC TCTTCATCCT TGACAGCTGG TGGGAGGAAC 2880
GGTCAGGGAG AAGGTTTAAG AATCAGAAGG GGAGGGTTCC CAGGGCCAGG GGGTCAGGCC 2940
AAGGTCAACA CAGGTCCCCT GATGAAGAAA CAGAAAGGAA GGAAGGACGA GGACTGGGCA 3000
AGAGGCTGTG GGAATGCAGG GCAAAGCCTG GCCAAGGAGC CGGCCTCTGC TATTGCAGGG 3060
AAAGGGAAGG GAAATGTGGC CCAAAGTGTG CCCAGAACCC AAGCGCCACA AGATACAAAG 3120
CCACACTACC ACAAAAAGGG GCTACAGGGT CCAATCACTA CCAGGAAAAG GGGCTACGGG 3180
GTCCAATCAC TACCAGGAAA AGGGGCTACG GGGTCCAATC ACTACCAGGA AAAGGGGCTA 3240
CGGGGTCCAA TCACTACCAG GAAAAGGGGC TACGGGGTCC AATCACTACC AGGAAAAGGG 3300
GCTACGGGCT CCAATCACTA CCAGGAAAAG GGGCTACAGG GTCCAATCAC TACCAGGAAA 3360
AGGGGCTACG GGGTCCAATC ACTACCAGGA AAAGGGGCTA CAGGGTCCAA TCACTACCAC 3420
AGAAAGGGGC TACGGGCTCC AATCACTACC AGGAAAAGGG GCTACGGGGT CCAATCACTA 3480
CCAGGAAAAG GGGCTACAGG GTCCAATCAC TACCAGGAAA AGGGGCTACG GGGTCCAATC 3540
ACTACCAGGA AAAGGGGCTA CGGGCTCCAA TCACTACCAG GAAAAGGGGC TACGGGGTCC 3600
AATCACTACC AGGAAAAGGG GCTACAGGGT CCAATCACTA CCAGGAAAAG GGGCTACAGG 3660 GTCCAATCAC TACCACAGAA AGGGGCTACG GGCTCCAATC ACTACCAGGA AAAGGGGCTA 3720 CGGGGTCCAA TCACTACCAG GAAAAGGGGC TACGGGCTCC AATCACTACC AGGAAAAGAG 3780 GCTATGGGGT CCAATCACTA CCAGGAAAAG GGGCTACGGG CTCCAATCAC TACCAGGAAA 3840 AGGGGCTATG GGGTCCAATC ACTACCACAG AAAGGGGCTA CGGGGTCCAA CGTCATCCGT 3900 AGAGAGCACG GAGACCCCCT CATCGAGGAG CTCAATCCCG GCGACGCCTT GGAGCCTGAG 3960 GGCCGGGGCA CAGGGGGTGT GGTGACCGAC TTCGACGGAG ACGGGATGCT GGACCTCATC 4020 TTGTCCCATG GAGAGTCCAT GGCTCAGCCG CTGTCCGTCT TCCGGGGCAA TCAGGGCTTC 4080 AACAACAACT GGCTGCGAGT GGTGCCACGC ACCCGGTTTG GGGCCTTTGC CAGGGGAGCT 4140 AAGGTCGTGC TCTACACCAA GAAGAGTGGG GCCCACCTGA GGATCATCGA CGGGGGCTCA 4200 GGCTACCTGT GTGAGATGGA GCCCGTGGCA CACTTTGGCC TGGGGAAGGA TGAAGCCAGC 4260 AGTGTGGAGG TGACGTGGCC AGATGGCAAG ATGGTGAGCC GGAACGTGGC CAGCGGGGAG 4320 ATGAACTCAG TGCTGGAGAT CCTCTACCCC CGGGATGAGG ACACACTTCA GGACCCAGCC 4380 CCACTGGAGT GTGGCCAAGG ATTCTCCCAG CAGGAAAATG GCCATTGCAT GGACACCAAT 4440 GAATGCATCC AGTTCCCATT CGTGTGCCCT CGAGACAAGC CCGTATGTGT CAACACCTAT 4500 GGAAGCTACA GGTGCCGGAC CAACAAGAAG TGCAGTCGGG GCTACGAGCC CAACGAGGAT 4560 GGCACAGCCT GCGTGGGTAC TGAGCTAGGC TCTAGGCATA CAATGACGTG GAAACCAAGG 4620 CCCAAAAAGG AGCTGCAACT TTCCCAAGGC ATCTGCACCC CCGTCTGGTC CTTTTTCCTG 4680 CCGGGTTGCC GGCTGCTCCT CAAAAGAGCT CAGCTCCAGG CTGCTCCCAG CACCCTTCTC 4740 CAGAAAGCTC CAGGTATTCC AGAAGCCCAA GTGTATGAAC AAGATCAGGA ATAA
Seq ID NO: 185 Protein sequence Protein Accession #: FGENESHH
11 21 31 41 51
I I I I I
MACPGGLPAR CSGWMGLGGP SGSSPASPPH SSSRYNGPNL VLKYDRAQKR LVNIAVDERS 60 SPYYALRDRQ GNAIGVTACD IDGDGREEIY FLNTNNAFSG HSSSAQVPSG LHRNRPVLKP 120 PPTTPAGLLG LPPLSGRDFS SSLGQASPDS RQGERVPVPC CRGGLRPTHE PEPFLLRPKS 180 GVATYTDKLF KFRNNRWEDI LSDEVNVARG VASLFAGRSV ACVDRKGSGR YSIYIANYAY 240 GNVGPDALIE MDPEASDLSR GILALRDVAA EAGVSKYTEG FSHTASPSIG EISGRTEERE 300 GGDPEEADEE HSGDGSTSQL CRLGWKDGQF KEEAAALVEE QREAGAAGVP RGRVRTALQT 360 SKSHLADKNL FGPPCYYSVC APSPAHPFPA RQAPQHYPVA PLVTQLMTHG RLAGKLARSV 420 PHPRAPGMDP KCKGRHAEPG LMAEALGAWP ALSTTWPGG LRSWEESRQK GQAMSRCALR 480 ELGGPWSQAT QHLPARELYD LGEPPILQRT DGDPGRRRDS PKVTQECHLV ATMPALGGLE 540 GPGRVAKREI GRETGAVGRP LSHPLVPNFP SCLRPLEAGT VPGAALPGNP GNWVLDMAKA 600 LAWNQMEKEE GKIHGDHEPR FRLRKAREAE FPPGSSEEPL LQFPSGLRGS PVLQVGLGLA 660 SATHCGSMSF LGGRGVSVGP ILSSSASDIF CDNENGPNFL FHNRGDGTFV DAAASAERRL 720 AFIVHLKYHL CRDFPHSLCH LAETGPSSSC CPWHARLLQA PHCHHGLSMS FTRTGSRFYS 780 FLTQGLASSA HRRTLSLQGS QGAPPCLLAR APCVLGSLIP TAYYIVLWSA IPESLMTHSY 840 LSSERVNVGV DDPHQHGRGV ALADFNRDGK VDIVYGNWNG PHRLYLQMST HGKVRFRDIA 900 SPKFSMPSPV RTVITADFDN DQELEIFFNN IAYRSSSANR LFRCSILARG SSSLTAGGRN 960 GQGEGLRIRR GGFPGPGGQA KVNTGPLMKK QKGRKDEDWA RGCGNAGQSL AKEPASAIAG 1020 KGKGNVAQSV PRTQAPQDTK PHYHKKGLQG PITTRKRGYG VQSLPGKGAT GSNHYQEKGL 1080 RGPITTRKRG YGVQSLPGKG ATGSNHYQEK GLQGPITTRK RGYGLQSLPG KGATGSNHYH 1140 RKGLRAPITT RKRGYGVQSL PGKGATGSNH YQEKGLRGPI TTRKRGYGLQ SLPGKGATGS 1200 NHYQEKGLQG PITTRKRGYR VQSLPQKGAT GSNHYQEKGL RGPITTRKRG YGLQSLPGKE 1260 AMGSNHYQEK GLRAPITTRK RGYGVQSLPQ KGATGSNVIR REHGDPLIEE LNPGDALEPE 1320 GRGTGGWTD FDGDGMLDLI LSHGESMAQP LSVFRGNQGF NNNWLRWPR TRFGAFARGA 1380 KWLYTKKSG AHLRIIDGGS GYLCEMEPVA HFGLGKDEAS SVEVTWPDGK MVSRNVASGE 1440 MNSVLEILYP RDEDTLQDPA PLECGQGFSQ QENGHCMDTN ECIQFPFVCP RDKPVCVNTY 1500 GSYRCRTNKK CSRGYEPNED GTACVGTELG SRHTMTWKPR PKKELQLSQG ICTPVWSFFL 1560 PGCRLLLKRA QLQAAPSTLL QKAPGIPEAQ VYEQDQE
Seq ID NO: 186 DNA sequence Nucleic Acid Accession #: NM_000584.1 Coding sequence: 75..374
1 11 21 31 41 51
A 1GCAGAGCAC A 1CAAGCTTCT A 1GGACAAGAG C 1CAGGAAGAA A 1CCACCGGAA G 1GAACCATCT 60
CACTGTGTGT AAACATGACT TCCAAGCTGG CCGTGGCTCT CTTGGCAGCC TTCCTGATTT 120
CTGCAGCTCT GTGTGAAGGT GCAGTTTTGC CAAGGAGTGC TAAAGAACTT AGATGTCAGT 180
GCATAAAGAC ATACTCCAAA CCTTTCCACC CCAAATTTAT CAAAGAACTG AGAGTGATTG 240
AGAGTGGACC ACACTGCGCC AACACAGAAA TTATTGTAAA GCTTTCTGAT GGAAGAGAGC 300
TCTGTCTGGA CCCCAAGGAA AACTGGGTGC AGAGGGTTGT GGAGAAGTTT TTGAAGAGGG 360
CTGAGAATTC ATAAAAAAAT TCATTCTCTG TGGTATCCAA GAATCAGTGA AGATGCCAGT 420
GAAACTTCAA GCAAATCTAC TTCAACACTT CATGTATTGT GTGGGTCTGT TGTAGGGTTG 480
CCAGATGCAA TACAAGATTC CTGGTTAAAT TTGAATTTCA GTAAACAATG AATAGTTTTT 540
CATTGTACCA TGAAATATCC AGAACATACT TATATGTAAA GTATTATTTA TTTGAATCTA 600
CAAAAAACAA CAAATAATTT TTAAATATAA GGATTTTCCT AGATATTGCA CGGGAGAATA 660
TACAAATAGC AAAATTGAGC CAAGGGCCAA GAGAATATCC GAACTTTAAT TTCAGGAATT 720
GAATGGGTTT GCTAGAATGT GATATTTGAA GCATCACATA AAAATGATGG GACAATAAAT 780
TTTGCCATAA AGTCAAATTT AGCTGGAAAT CCTGGATTTT TTTCTGTTAA ATCTGGCAAC 840
CCTAGTCTGC TAGCCAGGAT CCACAAGTCC TTGTTCCACT GTGCCTTGGT TTCTCCTTTA 900
TTTCTAAGTG GAAAAAGTAT TAGCCACCAT CTTACCTCAC AGTGATGTTG TGAGGACATG 960
TGGAAGCACT TTAAGTTTTT TCATCATAAC ATAAATTATT TTCAAGTGTA ACTTATTAAC 1020
CTATTTATTA TTTATGTATT TATTTAAGCA TCAAATATTT GTGCAAGAAT TTGGAAAAAT 1080
AGAAGATGAA TCATTGATTG AATAGTTATA AAGATGTTAT AGTAAATTTA TTTTATTTTA 1140
GATATTAAAT GATGTTTTAT TAGATAAATT TCAATCAGGG TTTTTAGATT AAACAAAGAA 1200
ACAATTGGGT ACCCAGTTAA ATTTTCATTT CAGATAAACA ACAAATAATT TTTTAGTATA 1260
AGTACATTAT TGTTTATCTG AAAGTTTTAA TTGAACTAAC AATCCTAGTT TGATACTCCC 1320
AGTCTTGTCA TTGCCAGCTG TGTTGGTAGT GCTGTGTTGA ATTACGGAAT AATGAGTTAG 1380
AACTATTAAA ACAGCCAAAA CTCCACAGTC AATATTAGTA ATTTCTTGCT GGTTGAAACT 1440
TGTTTATTAT GTACAAATAG ATTCTTATAA TATTATTTAA ATGACTGCAT TTTTAAATAC 1500 AAGGCTTTAT ATTTTTAACT TTAAGATGTT TTTATGTGCT CTCCAAATTT TTTTTACTGT 1560 TTCTGATTGT ATGGAAATAT AAAAGTAAAT ATGAAACATT TAAAATATAA TTTGTTGTCA 1620 AAGTAAAAAA AAAAAAAAA
Seq ID NO : 187 Protein sequence Protein Accession tt : NP 000575 .1
1 11 21 31 41 51
I I I I I I
MTSKLAVALL AAFLISAALC EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH 60
CANTEIIVKL SDGRELCLDP KENWVQRWE KFLKRAENS
Seq ID NO: 188 DNA sequence
Nucleic Acid Accession #: NM_003661.1
Coding sequence: 1..1152
1 11 21 31 41 51 1 1 1 1 1 | 1 | 1 | 1 ATGAGTGCAC TTTTCCTTGG TGTGGGAGTG AGGGCAGAGG AAGCTGGAGC GAGGGTGCAA 60
CAAAACGTTC CAAGTGGGAC AGATACTGGA GATCCTCAAA GTAAGCCCCT CGGTGACTGG 120
GCTGCTGGCA CCATGGACCC AGAGAGCAGT ATCTTTATTG AGGATGCCAT TAAGTATTTC 180
AAGGAAAAAG TGAGCACACA GAATCTGCTA CTCCTGCTGA CTGATAATGA GGCCTGGAAC 240
GGATTCGTGG CTGCTGCTGA ACTGCCCAGG AATGAGGCAG ATGAGCTCCG TAAAGCTCTG 300
GACAACCTTG CAAGACAAAT GATCATGAAA GACAAAAACT GGCACGATAA AGGCCAGCAG 360
TACAGAAACT GGTTTCTGAA AGACTTTCCT CGGTTGAAAA GTGAGCTTGA GGATAACATA 420
AGAAGGCTCC GTGCCCTTGC AGATGGGGTT CAGAAGGTCC ACAAAGGCAC CACCATCGCC 480
AATGTGGTGT CTGGCTCTCT CAGCATTTCC TCTGGCATCC TGACCCTCGT CGGCATGGGT 540
CTGGCACCCT TCACAGAGGG AGGCAGCCTT GTACTCTTGG AACCTGGGAT GGAGTTGGGA 600
ATCACAGCCG CTTTGACCGG GATTACCAGC AGTACCATGG ACTACGGAAA GAAGTGGTGG 660
ACACAAGCCC AAGCCCACGA CCTGGTCATC AAAAGCCTTG ACAAATTGAA GGAGGTGAGG 720
GAGTTTTTGG GTGAGAACAT ATCCAACTTT CTTTCCTTAG CTGGCAATAC TTACCAACTC 780
ACACGAGGCA TTGGGAAGGA CATCCGTGCC CTCAGACGAG CCAGAGCCAA TCTTCAGTCA 840
GTACCGCATG CCTCAGCCTC ACGCCCCCGβ GTCACTGAGC CAATCTCAGC TGAAAGCGGT 900
GAACAGGTGG AGAGGGTTAA TGAACCCAGC ATCCTGGAAA TGAGCAGAGG AGTCAAGCTC 960
ACGGATGTGG CCCCTGTAAG CTTCTTTCTT GTGCTGGATG TAGTCTACCT CGTGTACGAA 1020
TCAAAGCACT TACATGAGGG GGCAAAGTCA GAGACAGCTG AGGAGCTGAA GAAGGTGGCT 1080
CAGGAGCTGG AGGAGAAGCT AAACATTCTC AACAATAATT ATAAGATTCT GCAGGCGGAC 1140
CAAGAACTGT GA
Seq ID NO: 189 Protein sequence
Protein Accession ft: NP_003652.1
1 11 21 31 41 51
1 1 1 | 1 I 1 I 1 | 1 MSALFLGVGV RAEEAGARVQ QNVPSGTDTG DPQSKPLGDW AAGTMDPESS IFIEDAIKYF 60
KEKVSTQNLL LLLTDNEAWN GFVAAAELPR NEADELRKAL DNLARQMIMK DKNWHDKGQQ 120
YRNWFLKEFP RLKSELEDNI RRLRALADGV QKVHKGTTIA NWSGSLSIS SGILTLVGMG 180
LAPFTEGGSL VLLEPGMELG ITAALTGITS STMDYGKKWW TQAQAHDLVI KSLDKLKEVR 240
EFLGENISNF LSLAGNTYQL TRGIGKDIRA LRRARANLQS VPHASASRPR VTEPISAESG 300
EQVERVNEPS ILEMSRGVKL TDVAPVSFFL VLDWYLVYE SKHLHEGAKS ETAEELKKVA 360
QELEEKLNIL NNNYKILQAD QEL
Seq ID NO: 190 DNA sequence
Nucleic Acid Accession # : NM_014452. Coding sequence: 1. .1968
11 21 31 41 51
ATGGGGACCT CTCCGAGCAG CAGCACCGCC CTCGCCTCCT GCAGCCGCAT CGCCCGCCGA 60 GCCACAGCCA CGATGATCGC GGGCTCCCTT CTCCTGCTTG GATTCCTTAG CACCACCACA 120 GCTCAGCCAG AACAGAAGGC CTCGAATCTC ATTGGCACAT ACCGCCATGT TGACCGTGCC 180 ACCGGCCAGG TGCTAACCTG TGACAAGTGT CCAGCAGGAA CCTATGTCTC TGAGCATTGT 240 ACCAACACAA GCCTGCGCGT CTGCAGCAGT TGCCCTGTGG GGACCTTTAC CAGGCATGAG 300 AATGGCATAG AGAAATGCCA TGACTGTAGT CAGCCATGCC CATGGCCAAT GATTGAGAAA 360 TTACCTTGTG CTGCCTTGAC TGACCGAGAA TGCACTTGCC CACCTGGCAT GTTCCAGTCT 420 AACGCTACCT GTGCCCCCCA TACGGTGTGT CCTGTGGGTT GGGGTGTGCG GAAGAAAGGG 480 ACAGAGACTG AGGATGTGCG GTGTAAGCAG TGTGCTCGGG GTACCTTCTC AGATGTGCCT 540 TCTAGTGTGA TGAAATGCAA AGCATACACA GACTGTCTGA GTCAGAACCT GGTGGTGATC 600 AAGCCGGGGA CCAAGGAGAC AGACAACGTC TGTGGCACAC TCCCGTCCTT CTCCAGCTCC 660 ACCTCACCTT CCCCTGGCAC AGCCATCTTT CCACGCCCTG AGCACATGGA AACCCATGAA 720 GTCCCTTCCT CCACTTATGT TCCCAAAGGC ATGAACTCAA CAGAATCCAA CTCTTCTGCC 780 TCTGTTAGAC CAAAGGTACT GAGTAGCATC CAGGAAGGGA CAGTCCCTGA CAACACAAGC 840 TCAGCAAGGG GGAAGGAAGA CGTGAACAAG ACCCTCCCAA ACCTTCAGGT AGTCAACCAC 900 CAGCAAGGCC CCCACCACAG ACACATCCTG AAGCTGCTGC CGTCCATGGA GGCCACTGGG 960 GGCGAGAAGT CCAGCACGCC CATCAAGGGC CCCAAGAGGG GACATCCTAG ACAGAACCTA 1020 CACAAGCATT TTGACATCAA TGAGCATTTG CCCTGGATGA TTGTGCTTTT CCTGCTGCTG 1080 GTGCTTGTGG TGATTGTGGT GTGCAGTATC CGGAAAAGCT CGAGGACTCT GAAAAAGGGG 1140 CCCCGGCAGG ATCCCAGTGC CATTGTGGAA AAGGCAGGGC TGAAGAAATC CATGACTCCA 1200 ACCCAGAACC GGGAGAAATG GATCTACTAC TGCAATGGCC ATGGTATCGA TATCCTGAAG 1260 CTTGTAGCAG CCCAAGTGGG AAGCCAGTGG AAAGATATCT ATCAGTTTCT TTGCAATGCC 1320 AGTGAGAGGG AGGTTGCTGC TTTCTCCAAT GGGTACACAG CCGACCACGA GCGGGCCTAC 1380 GCAGCTCTGC AGCACTGGAC CATCCGGGGC CCCGAGGCCA GCCTCGCCCA GCTAATTAGC 1440 GCCCTGCGCC AGCACCGGAG AAACGATGTT GTGGAGAAGA TTCGTGGGCT GATGGAAGAC 1500 ACCACCCAGC TGGAAACTGA CAAACTAGCT CTCCCGATGA GCCCCAGCCC GCTTAGCCCβ 1560 AGCCCCATCC CCAGCCCCAA CGCGAAACTT GAGAATTCCG CTCTCCTGAC GGTGGAGCCT 1620 TCCCCACAGG ACAAGAACAA GGGCTTCTTC GTGGATGAGT CGGAGCCCCT TCTCCGCTGT 1680 GACTCTACAT CCAGCGGCTC CTCCGCGCTG AGCAGGAACG GTTCCTTTAT TACCAAAGAA 1740 AAGAAGGACA CAGTGTTGCG GCAGGTACGC CTGGACCCCT GTGACTTGCA GCCTATCTTT 1800 GATGACATGC TCCACTTTCT AAATCCTGAG GAGCTGCGGG TGATTGAAGA GATTCCCCAG 1860 GCTGAGGACA AACTAGACCG GCTATTCGAA ATTATTGGAG TCAAGAGCCA GGAAGCCAGC 1920 CAGACCCTCC TGGACTCTGT TTATAGCCAT CTTCCTGACC TGCTGTAG
Seq ID NO: 191 Protein sequence Protein Accession ft: NP 055267.1
1 11 21 31 41 51 1 1 t 1 | 1 | 1 | 1 1 MGTSPSSSTA LASCSRIARR ATATMIAGSL LLLGFLSTTT AQPEQKASNL IGTYRHVDRA 60
TGQVLTCDKC PAGTYVSEHC TNTSLRVCSS CPVGTFTRHE NGIEKCHDCS QPCPWPMIEK 120
LPCAALTDRE CTCPPGMFQS NATCAPHTVC PVGWGVRKKG TETEDVRCKQ CARGTFSDVP 180
SSVMKCKAYT DCLSQNLWI KPGTKETDNV CGTLPSFSSS TSPSPGTAIF PRPEHMETHE 240
VPSSTYVPKG MNSTESNSSA SVRPKVLSSI QEGTVPDNTS SARGKEDVNK TLPNLQWNH 300
QQGPHHRHIL KLLPSMEATG GEKSSTPIKG PKRGHPRQNL HKHFDINEHL PWMIVLFLLL 360
VLWIWCSI RKSSRTLKKG PRQDPSAIVE KAGLKKSMTP TQNREKWIYY CNGHGIDILK 420
LVAAQVGSQW KDIYQFLCNA SEREVAAFSN GYTADHERAY AALQHWTIRG PEASLAQLIS 480
ALRQHRRNDV VEKIRGLMED TTQLETDKLA LPMSPSPLSP SPIPSPNAKL ENSALLTVEP 540
SPQDKNKGFF VDESEPLLRC DSTSSGSSAL SRNGSFITKE KKDTVLRQVR LDPCDLQPIF 600
DDMLHFLNPE ELRVIEEIPQ AEDKLDRLFE IIGVKSQEAS QTLLDSVYSH LPDLL
Seq ID NO: 192 DNA sequence
Nucleic Acid Accession #: XM_044533 Coding sequence: 238..2751
1 11 21 31 41 51
G ICTCTGCCCA AIGCCGAGGCT GICGGGGCCGG CIGCCGGCGGG AIGGACTGCGG TIGCCCCGCGG 60
AGGGGCTGAG TTTGCCAGGG CCCACTTGAC CCTGTTTCCC ACCTCCCGCC CCCCAGGTCC 120
GGAGGCGGGG GCCCCCGGGG CGACTCGGGG GCGGACCGCG GGGCGGAGCT GCCGCCCGTG 180
AGTCCGGCCG AGCCACCTGA GCCCGAGCCG CGGGACACCG TCGCTCCTGC TCTCCGAATG 240
CTGCGCACCG CGATGGGCCT GAGGAGCTGG CTCGCCGCCC CATGGGGCGC GCTGCCGCCT 300
CGGCCACCGC TGCTGCTGCT CCTGCTGCTG CTGCTCCTGC TGCAGCCGCC GCCTCCGACC 360
TGGGCGCTCA GCCCCCGGAT CAGCCTGCCT CTGGGCTCTG AAGAGCGGCC ATTCCTCAGA 420
TTCGAAGCTG AACACATCTC CAACTACACA GCCCTTCTGC TGAGCAGGGA TGGCAGGACC 480
CTGTACGTGG GTGCTCGAGA GGCCCTCTTT GCACTCAGTA GCAACCTCAG CTTCCTGCCA 540
GGCGGGGAGT ACCAGGAGCT GCTTTGGGGT GCAGACGCAG AGAAGAAACA GCAGTGCAGC 600
TTCAAGGGCA AGGACCCACA GCGCGACTGT CAAAACTACA TCAAGATCCT CCTGCCGCTC 660
AGCGGCAGTC ACCTGTTCAC CTGTGGCACA GCAGCCTTCA GCCCCATGTG TACCTACATC 720
AACATGGAGA ACTTCACCCT GGCAAGGGAC GAGAAGGGGA ATGTCCTCCT GGAAGATGGC 780
AAGGGCCGTT GTCCCTTCGA CCCGAATTTC AAGTCCACTG CCCTGGTGGT TGATGGCGAG 840
CTCTACACTG GAACAGTCAG CAGCTTCCAA GGGAATGACC CGGCCATCTC GCGGAGCCAA 900
AGCCTTCGCC CCACCAAGAC CGAGAGCTCC CTCAACTGGC TGCAAGACCC AGCTTTTGTG 960
GCCTCAGCCT ACATTCCTGA GAGCCTGGGC AGCTTGCAAG GCGATGATGA CAAGATCTAC 1020
TTTTTCTTCA GCGAGACTGG CCAGGAATTT GAGTTCTTTG AGAACACCAT TGTGTCCCGC 1080
ATTGCCCGCA TCTGCAAGGG CGATGAGGGT GGAGAGCGGG TGCTACAGCA GCGCTGGACC 1140
TCCTTCCTCA AGGCCCAGCT GCTGTGCTCA CGGCCCGACG ATGGCTTCCC CTTCAACGTG 1200
CTGCAGGATG TCTTCACGCT GAGCCCCAGC CCCCAGGACT GGCGTGACAC CCTTTTCTAT 1260
GGGGTCTTCA CTTCCCAGTG GCACAGGGGA ACTACAGAAG GCTCTGCCGT CTGTGTCTTC 1320
ACAATGAAGG ATGTGCAGAG AGTCTTCAGC GGCCTCTACA AGGAGGTGAA CCGTGAGACA 1380
CAGCAGTGGT ACACCGTGAC CCACCCGGTG CCCACACCCC GGCCTGGAGC GTGCATCACC 1440
AACAGTGCCC GGGAAAGGAA GATCAACTCA TCCCTGCAGC TCCCAGACCG CGTGCTGAAC 1500
TTCCTCAAGG ACCACTTCCT GATGGACGGG CAGGTCCGAA GCCGCATGCT GCTGCTGCAG 1560
CCCCAGGCTC GCTACCAGCG CGTGGCTGTA CACCGCGTCC CTGGCCTGCA CCACACCTAC 1620
GATGTCCTCT TCCTGGGCAC TGGTGACGGC CGGCTCCACA AGGCAGTGAG CGTGGGCCCC 1680
CGGGTGCACA TCATTGAGGA GCTGCAGATC TTCTCATCGG GACAGCCCGT GCAGAATCTG 1740
CTCCTGGACA CCCACAGGGG GCTGCTGTAT GCGGCCTCAC ACTCGGGCGT AGTCCAGGTG 1800
CCCATGGCCA ACTGCAGCCT GTACAGGAGC TGTGGGGACT GCCTCCTCGC CCGGGACCCC 1860
TACTGTGCTT GGAGCGGCTC CAGCTGCAAG CACGTCAGCC TCTACCAGCC TCAGCTGGCC 1920
ACCAGGCCGT GGATCCAGGA CATCGAGGGA GCCAGCGCCA AGGACCTTTG CAGCGCGTCT 1980
TCGGTTGTGT CCCCGTCTTT TGTACCAACA GGGGAGAAGC CATGTGAGCA AGTCCAGTTC 2040
CAGCCCAACA CAGTGAACAC TTTGGCCTGC CCGCTCCTCT CCAACCTGGC GACCCGACTC 2100
TGGCTACGCA ACGGGGCCCC CGTCAATGCC TCGGCCTCCT GCCACGTGCT ACCCACTGGG 2160
GACCTGCTGC TGGTGGGCAC CCAACAGCTG GGGGAGTTCC AGTGCTGGTC ACTAGAGGAG 2220
GGCTTCCAGC AGCTGGTAGC CAGCTACTGC CCAGAGGTGG TGGAGGACGG GGTGGCAGAC 2280
CAAACAGATG AGGGTGGCAG TGTACCCGTC ATTATCAGCA CATCGCGTGT GAGTGCACCA 2340
GCTGGTGGCA AGGCCAGCTG GGGTGCAGAC AGGTCCTACT GGAAGGAGTT CCTGGTGATG 2400
TGCACGCTCT TTGTGCTGGC CGTGCTGCTC CCAGTTTTAT TCTTGCTCTA CCGGCACCGG 2460
AACAGCATGA AAGTCTTCCT GAAGCAGGGG GAATGTGCCA GCGTGCACCC CAAGACCTGC 2520
CCTGTGGTGC TGCCCCCTGA GACCCGCCCA CTCAACGGCC TAGGGCCCCC TAGCACCCCG 2S80
CTCGATCACC GAGGGTACCA GTCCCTGTCA GACAGCCCCC CGGGGTCCCG AGTCTTCACT 2640
GAGTCAGAGA AGAGGCCACT CAGCATCCAA GACAGCTTCG TGGAGGTATC CCCAGTGTGC 2700
CCCCGGCCCC GGGTCCGCCT TGGCTCGGAG ATCCGTGACT CTGTGGTGTG AGAGCTGACT 2760
TCCAGAGGAC GCTGCCCTGG CTTCAGGGGC TGTGAATGCT CGGAGAGGGT CAACTGGACC 2820
TCCCCTCCGC TCTGCTCTTC GTGGAACACG ACCGTGGTGC CCGGCCCTTG GGAGCCTTGG 2880
GGCCAGCTGG CCTGCTGCTC TCCAGTCAAG TAGCGAAGCT CCTACCACCC AGACACCCAA 2940
ACAGCCGTGG CCCCAGAGGT CCTGGCCAAA TATGGGGGCC TGCCTAGGTT GGTGGAACAG 3000
TGCTCCTTAT GTAAACTGAG CCCTTTGTTT AAAAAACAAT TCCAAATGTG AAACTAGAAT 3060
GAGAGGGAAG AGATAGCATG GCATGCAGCA CACACGGCTG CTCCAGTTCA TGGCCTCCCA 3120
GGGGTGCTGG GGATGCATCC AAAGTGGTTG TCTGAGACAG AGTTGGAAAC CCTCACCAAC 3180 TGGCCTCTTC ACCTTCCACA TTATCCCGCT GCCACCGGCT GCCCTGTCTC ACTGCAGATT 3240
CAGGACCAGC TTGGGCTGCG TGCGTTCTGC CTTGCCAGTC AGCCGAGGAT GTAGTTGTTG 3300
CTGCCGTCGT CCCACCACCT CAGGGACCAG AGGGCTAGGT TGGCACTGCG GCCCTCACCA 3360
GGTCCTGGGC TCGGACCCAA CTCCTGGACC TTTCCAGCCT GTATCAGGCT GTGGCCACAC 3420
GAGAGGACAG CGCGAGCTCA GGAGAGATTT CGTGACAATG TACGCCTTTC CCTCAGAATT 3480
CAGGGAAGAG ACTGTCGCCT GCCTTCCTCC GTTGTTGCGT GAGAACCCGT GTGCCCCTTC 3540
CCACCATATC CACCCTCGCT CCATCTTTGA ACTCAAACAC GAGGAACTAA CTGCACCCTG 3600
GTCCTCTCCC CAGTCCCCAG TTCACCCTCC ATCCCTCACC TTCCTCCACT CTAAGGGATA 3660
TCAACACTGC CCAGCACAGG GGCCCTGAAT TTATGTGGTT TTTATACATT TTTTAATAAG 3720 ATGCACTTTA TGTCATTTTT TAATAAAGTC TGAAGAATTA CTGTTT
Seq ID NO: 193 Protein sequence Protein Accesεion tf: XP_044533.3
1 11 21 31 41 51
M ILRTAMGLRS WILAAPWGALP PIRPPLLLLLL LILLLLQPPPP TIWALSPRISL PILGSEERPFL 60
RFEAEHISNY TALLLSRDGR TLYVGAREAL FALSSNLSFL PGGEYQELLW GADAEKKQQC 120
SFKGKDPQRD CQNYIKILLP LSGSHLFTCG TAAFSPMCTY INMENFTLAR DEKGNVLLED 180
GKGRCPFDPN FKSTALWDG ELYTGTVSSF QGNDPAISRS QSLRPTKTES SLNWLQDPAF 240
VASAYIPESL GSLQGDDDKI YFFFSETGQE FEFFENTIVS RIARICKGDE GGERVLQQRW 300
TSFLKAQLLC SRPDDGFPFN VLQDVFTLSP SPQDWRDTLF YGVFTSQWHR GTTEGSAVCV 360
FTMKDVQRVF SGLYKEVNRE TQQWYTVTHP VPTPRPGACI TNSARERKIN SSLQLPDRVL 420
NFLKDHFLMD GQVRSRMLLL QPQARYQRVA VHRVPGLHHT YDVLFLGTGD GRLHKAVSVG 480
PRVHIIEELQ IFSSGQPVQN LLLDTHRGLL YAASHSGWQ VPMANCSLYR SCGDCLLARD 540
PYCAWSGSSC KHVSLYQPQL ATRPWIQDIE GASAKDLCSA SSWSPSFVP TGEKPCEQVQ 600
FQPNTVNTLA CPLLSNLATR LWLRNGAPVN ASASCHVLPT GDLLLVGTQQ LGEFQCWSLE 660
EGFQQLVASY CPEWEDGVA DQTDEGGSVP VIISTSRVSA PAGGKASWGA DRSYWKEFLV 720
MCTLFVLAVL LPVLFLLYRH RNSMKVFLKQ GECASVHPKT CPWLPPETR PLNGLGPPST 780 PLDHRGYQSL SDSPPGSRVF TESEKRPLSI QDSFVEVSPV CPRPRVRLGS EIRDSW
Seq ID NO: 194 DNA sequence
Nucleic Acid Accession if: NM_022819.1
Coding sequence: 1..635
1 11 21 31 41 51
I I I I I I
ATGGCAGATG GGGCAAAGGC CAACCCCAAA GGGTTCAAAA AGAAGGTGCT GGATAGATGC 60
TTCTCTGGGT GGAGGGGCCC ACGCTTCGGG GCCTCCTGTC CTTCAAGAAC CTCCAGGTCT 120
AGCCTGGGTA TGAAGAAGTT CTTCACCGTG GCCATCCTTG CTGGCAGGGT TCTGTCCACA 180
GCTCACGGCA GCCTGCTCAA CCTGAAGGCC ATGGTGGAGG CCGTCACAGG GAGGAGCGCC 240
ATCCTGTCCT TCGTGGGCTA CGGTTGCTAC TGTGGGCTGG GGGGCCGTGG CCAGCCCAAG 300
GATGAGGTGG ACTGGTGCTG CCACGCCCAC GACTGCTGCT ACCAGGAACT CTTTGACCAA 360
GGCTGTCACC CCTATGTGGA CCACTATGAT CACACCATCG AGAACAACAC TGAGATAGTC 420
TGCAGTGACC TCAACAAGAC AGAGTGTGAC AAGCAGACAT GCATGTGTGA CAAGAACATG 480
GTTCTGTGCC TCATGAACCA GACGTACCGA GAGGAGTACC GTGGCTTCCT CAATGTCTAC 540
TGCCAGGGCC CCACGCCCAA CTGCAGCATC TATGAACCGC CCCCTGAGGA GGTCACCTGC 600 AGTCACCAAT CCCCAGCGCC CCCCGCCCCT CCCTAG
Seq ID NO: 195 Protein sequence Protein Accession ft: NP_073730
1 11 21 31 41 51
I I I I I I
MADGAKANPK GFKKKVLDRC FSGWRGPRFG ASCPSRTSRS SLGMKKFFTV AILAGSVLST 60
AHGSLLNLKA MVEAVTGRSA ILSFVGYGCY CGLGGRGQPK DEVDWCCHAH DCCYQELFDQ 120
GCHPYVDHYD HTIENNTEIV CSDLNKTECD KQTCMCDKNM VLCLMNQTYR EEYRGFLNVY 180 CQGPTPNCSI YEPPPEEVTC SHQSPAPPAP P
Seq ID NO: 196 DNA sequence
Nucleic Acid Accession ft: XM_028196.1
Coding sequence: 1315..1791 1 11 21 31 41 51 i i i i i i
GGCATTGATG GTGTGTGCGC CTGCGTGTGT GTGTGTGTGT GTGTGTGTGT GTGTGTGTGT 60
GTGTGTGTGT GTCTGGAGTC ATGGCAGGGT CCCTTTCTGT CTGTCTCCTT GCTCTGCCCC 120
AGACTGGGGG GCTGCAGAGG TGAGGGTATC TGGCCTCAAC AGCTGCTTAT TCCCGATGGG 180
ATGGCCTGGG CTGGGCCCCT GAGGCCAGGC TGACTTGGAC ATGGCAAGAG GGGTCCCAGG 240
CTCTTGTGGG CAAAGCAGGG GAGGCGCCAA TGTGGAGGAA CAGAGTCTCC TGGCTGGCTG 300
CTGCTCTCTG GAGCGGGTGG AGTCAGGGAA GAGCTGAGCT GGGGAGTCAC CCTGGGCCTG 360
GGGTCACCGT AGGCCCCATG TAGCACCCTG GTTCCCCTGC CTGTAGGTGA CAGGAGCCAG 420
CCCAGCCAGG TGTGCTCCCT CCCCAGGCCC TAGGCAGGCG GGTACAGGGG CCAGCAGCTG 480
CGCCCGCCCC ACCTTCCTTC CCACCCACAT GCCGAAGGGT GGCCAGGCAG GCAGGTGGAC 540
GAGTCCAGGC AGCGGCTGAG TCAGTGTGTG TGGAATGTTC TGGCCGCTCC CAGCTGCACC 600
CTGCCCCTAC CTGCCACCAC CTCACCTTCA TCCTCAGGCG CTGCGGCCCT GAGCCCCTGC 660
CAGGAATGCA CCTTTAGCCC AGGCCTGCTC AGTGAGCTCC GCCGACAGCC AGCCCTGCTC 720
CTCCCGCCAT GACCCTGCAG ACCCCTCTGG GCTTCCAAGT TCCTGGGGGC TGCAGTGAAC 780
ATGCTCCACC TGCATGGCTG GCAAACCATG GTGGGCCCCA GCTGTGGTGC GTGCTGGGGT 840
AGAGGCAAGG AAGTGATGGG ACCGCAGAGA TGAGACCCCC AGGGATGAGA TGGGACCCCC 900
AGGCAGGGCC CAGGGTCCAG GGCCCAGGAG AGAGAAGCAG GGAGGGAGAG AGCTTCCTGG 960
TGGAGGACGC ATCCTACAGT GGGGGCAAGG GTGCTCTGAG GTCCGGTGAA GGCAGGGACT 1020
AGGCTGCCCA GGCCCTGCCT GCTTGGCTGG GGCTGGGGGC TGCTGGGAGG TGGCTGGGAG 1080
GCTGGGCCTG GGCAGCTAAG CTGGAGCTTT GGCCAGGGTC CAGAGCCTCC CTCCCTTCAG 1140 CTTCCTGCTG CACAGAACCC TCGCCCCTGG CCACCCCGTG CTGCCTCCTT GCCCTGGCAG 1200 ACCCAGCACT GGCTGCTGCT AGTCAGATGG GGTAGCGGGC AGGGGCCGGA GGGGCCACCC 1260 TCCCAGCTGA CCCAGCCTCC TGGGCCGCTT CTTCCAAACC AGCAGGGTAG AAAGATGGGG 1320 CACCCACCAG TCTCTCCCAG TGCCCCGGCC CCAGCTGGCA CCACAGCTAT ACCTGGGCTT 1380 ATTCCAGACC TTGTCGCCGG GACCCCCTGT GAGTTGTGGG ATTCCCAAGA GGGGTGTGGG 1440 GATAACCCAG CCAAGTGGGG GCTGCAGCTG TCCACAGATG CACTCAGCCT GGCCTCTACC 1500 CCAGGGCCCC GCTGGGCTCT CATTGCCGGC GCCCTTGCCG CGGGCGTCCT CCTCGTCTCC 1560 TGCCTCCTCT GTGCTGCCTG CTGCTGCTGC CGCCGCCACA GGAAGAAGCC CAGGGACAAG 1620 GAGTCCGTGG GTCTGGGCAG TGCCCGCGGC ACCACCACCA CCCACCTGGT GAGGAGCGGC 1680 TCCTTGCTCA CTCAGTCCAG AGAGGGCTTG AAATCCAGGC TCCAGAGCCC AGGGCAGCGA 1740 GGCGAGTTCA GCCCCAGGGA TGGTTTAACC CCCACAGAGG CAGGGCGTTG AGGACCTTCC 1800 TGGCAGGGAA AGTGGGTGAA CAGAGGTGAG AAGGAGGCCA TGCAACAGGG GCTGCCCCAT 1860 GGGCCCGAGG GAGCCACAGC GGGTTCTTGA GGAAGGCAGG GGGTACCCCA GATGCCACGT 1920 TTTGGGTGGG TTTGGCCGGT CTCACAGAGC GAAGCCGACG ATTTGTGCCT GTTGGGTGGC 1980 CTGGCCTGGA GGCGGGGGGT CTTGACCCAT GTCATGCAAG GGCTGCCCGG GAGCCCAGGG 2040 CTCTGATGAG GCATGATGTC AGGACCACCT GCCCCTTGTC CCAACTCACT CCAGGTGCAA 2100 CCTGATGTGG ATGGCCTGGA GTCCAGCCCG GGGGATGCTC AGCAATGGGG GTGCCTGCAG 2160 CTCTCCCTGG AGTTCGACTT TGGAAGCCAG GAGGTGAAGG GCCCCGCTGC GCAGGACCAG 2220 CGGTTCTGCG AGTTTCCGGA AAGGGTGACG GGGGAAGGGC AGACCCCATG CCCTGGGTGG 2280 TGGGGAGCTG ACAGGGCAGG GGCCCTTGGC TGAGCCCACC CCGCTGGCTC CCAGATCAGG 2340 GTGGGCCTGA GGCAGGCAGC CGACCTGAGG CCTGGGGGCA CCGTGGACCC CTATGCCCGG 2400 GTCAGCGTCT CCACCCAGGC CGGACACAGA CATGAGACAA AAGTGCACCG AGGCACGCTC 2460 TGCCCCGTGT TTGACGAGAC CTGCTGCTTC CACGTGAGTC AGGGATGGTC GGCTGGGTGG 2520 GCCTGGACGG CTGGATGGGC CTGGGCTGGG TGGGCCTGGG CAGCTGGGTG GGCCTGGGCA 2580 GCTGGGTGGG CCTGAGCTAG GGCAGCAGGG CCTGGCTCAC GCCGCTGCCT CAGATCCCGC 2640 AGGCGGAGCT GCCAGGGGCC ACCCTGCAGG TGCAGCTTTT CAACTTCAAG CGCTTCTCGG 2700 GGCATGAGCC CCTGGGTGAG CTCCGTCTGC CACTGGGCAC CGTGGATCTG CAGCATGTTC 2760 TGGAGCACTG GTACCTGCTG GGCCCGCCGG CTGCCACTCA GGTGAGGTGC TGGTCACCAG 2820 GCCACAGCCC AAGGCAGAGC TGGCAGGGAC CCTGCCCTAT GGGCCATCGG AAAGACAGGC 2880 CTGATGGGCA GCATTTTCGG GGGTCTGAGC CCCAACTCGG CCAGAATCAC CCTCCCGGGC 2940 TGAAGCCCCT CTTGCTGCCC AGAGCCCGAG CAGGTCGGGG AGCTGTGCTT CTCTCTCCGG 3000 TACGTGCCCA GCTCAGGCCG GCTGACCGTG GTGGTGCTGG AGGCTCGAGG CCTGCGTCCA 3060 GGACTTGCAG AGCCCTACGT GAAGGTCCAG CTCATGCTGA ACCAGAGGAA GTGGAAGAAG 3120 AGAAAGACAG CCACCAAAAA GGGCACGGCG GCCCCCTACT TCAATGAGGC CTTCACCTTC 3180 CTGGTGCCCT TCAGCCAGGT CCAGAATGTG GACCTGGTGC TGGCTGTCTG GGACCGCAGC 3240 CTGCCGCTCC GAACTGAGCC CGTAGGCAAG GTGCACCTGG GTGCCCGGGC CTCGGGGCAG 3300 CCCCTGCAGC ACTGGGCAGA CATGCTGGCC CACGCCCGGC GGCCCATTGC CCAGCGGCAC 3360 CCCCTGCGGC CAGCCAGGGA GGTGGACCGC ATGCTGGCCC TGCAGCCCCG CCTTCGCCTG 3420 CGCCTGCCCT TGCCCCACTC CTGAATGCAC CACATGCCTC TGTCTCCCCG CTGAGCCCAG 3480 GCACTTGCCC AGGCCGCCCT GCAGGACCAC TGCAATAAAC GCCTTCTCCT GCC
Seq ID NO: 197 Protein εequence Protein Acceεsion ft: XP_028196.1
1 11 21 31 41 51
I I i I I I
MGHPPVSPSA PAPAGTTAIP GLIPDLVAGT PCELWDSQEG CGDNPAKWGL QLSTDALSLA 60 STPGPRWALI AGALAAGVLL VSCLLCAACC CCRRHRKKPR DKESVGLGSA RGTTTTHLVR 120 SGSLLTQSRE GLKSRLQSPG QRGEFSPRDG LTPTEAGR
Seq ID NO: 198 DNA sequence
Nucleic Acid Accession ft: NM_000612.2
Coding sequence: 553..1095
11 21 31 41 51
I I I I I
TTCTCCCGCA ACCTTCCCTT CGCTCCCTCC CGTCCCCCCC AGCTCCTAGC CTCCGACTCC 60 CTCCCCCCCT CACGCCCGCC CTCTCGCCTT CGCCGAACCA AAGTGGATTA ATTACACGCT 120 TTCTGTTTCT CTCCGTGCTG TTCTCTCCCG CTGTGCGCCT GCCCGCCTCT CGCTGTCCTC 180 TCTCCCCCTC GCCCTCTCTT CGGCCCCCCC CTTTCACGTT CACTCTGTCT CTCCCACTAT 240 CTCTGCCCCC CTCTATCCTT GATACAACAG CTGACCTCAT TTCCCGATAC CTTTTCCCCC 300 CCGAAAAGTA CAACATCTGG CCCGCCCCAG CCCGAAGACA GCCCGTCCTC CCTGGACAAT 360 CAGACGAATT CTCCCCCCCC CCCCAAAAAA AAAAGCCATC CCCCCGCTCT GCCCCGTCGC 420 ACATTCGGCC CCCGCGACTC GGCCAGAGCG GCGCTGGCAG AGGAGTGTCC GGCAGGAGGG 480 CCAACGCCCG CTGTTCGGTT TGCGACACGC AGCAGGGAGG TGGGCGGCAG CGTCGCCGGC 540 TTCCAGACAC CAATGGGAAT CCCAATGGGG AAGTCGATGC TGGTGCTTCT CACCTTCTTG 600 GCCTTCGCCT CGTGCTGCAT TGCTGCTTAC CGCCCCAGTG AGACCCTGTG CGGCGGGGAG 660 CTGGTGGACA CCCTCCAGTT CGTCTGTGGG GACCGCGGCT TCTACTTCAG CAGGCCCGCA 720 AGCCGTGTGA GCCGTCGCAG CCGTGGCATC GTTGAGGAGT GCTGTTTCCG CAGCTGTGAC 780 CTGGCCCTCC TGGAGACGTA CTGTGCTACC CCCGCCAAGT CCGAGAGGGA CGTGTCGACC 840 CCTCCGACCG TGCTTCCGGA CAACTTCCCC AGATACCCCG TGGGCAAGTT CTTCCAATAT 900 GACACCTGGA AGCAGTCCAC CCAGCGCCTG CGCAGGGGCC TGCCTGCCCT CCTGCGTGCC 960 CGCCGGGGTC ACGTGCTCGC CAAGGAGCTC GAGGCGTTCA GGGAGGCCAA ACGTCACCGT 1020 CCCCTGATTG CTCTACCCAC CCAAGACCCC GCCCACGGGG GCGCCCCCCC AGAGATGGCC 1080 AGCAATCGGA AGTGAGCAAA ACTGCCGCAA GTCTGCAGCC CGGCGCCACC ATCCTGCAGC 1140 CTCCTCCTGA CCACGGACGT TTCCATCAGG TTCCATCCCG AAAATCTCTC GGTTCCACGT 1200 CCCCCTGGGG CTTCTCCTGA CCCAGTCCCC GTGCCCCGCC TCCCCGAAAC AGGCTACTCT 1260 CCTCGGCCCC CTCCATCGGG CTGAGGAAGC ACAGCAGCAT CTTCAAACAT GTACAAAATC 1320 GATTGGCTTT AAACACCCTT CACATACCCT CCCCCC
Seq ID NO: 199 Protein sequence Protein Accesεion ft: NP 000603.1
51 l l l l l !
MGIPMGKSML VLLTFLAFAS CCIAAYRPSE TLCGGELVDT LQFVCGDRGF YFSRPASRVS 60 RRSRGIVEEC CFRSCDLALL ETYCATPAKS ERDVSTPPTV LPDNFPRYPV GKFFQYDTWK 120 QSTQRLRRGL PALLRARRGH VLAKELEAFR EAKRHRPLIA LPTQDPAHGG APPEMASNRK
Seq ID NO: 200 DNA εequence Nucleic Acid Acceεεion it: AK057131. Coding εequence: 61..1146
60
120
Figure imgf001034_0001
180
TCTCAGTTCA GCAAAGAGGA ACGCGTCGCG ATGAAAGAGG CGCTGAAAGG TGCCATCCAG 240
ATTCCAACAG TGACTTTTAG CTCTGAGAAG TCCAATACTA CAGCCCTGGC TGAGTTCGGA 300
AAATACATTC ATAAAGTCTT TCCTACAGTG GTCAGCACCA GCTTTATCCA GCATGAAGTC 360
GTGGAAGAGT ATAGCCACCT GTTCACTATC CAAGGCTCGG ACCCCAGCTT GCAGCCCTAC 420
CTGCTGATGG CTCACTTTGA TGTGGTGCCT GCCCCTGAAG AAGGCTGGGA GGTGCCCCCA 480
TTCTCTGGGT TGGAGCGTGA TGGCGTCATC TATGGTTGGG GCACACTGGA CGACAAGAAC 540
TCTGTGATGG CATTACTGCA GGCCTTGGAG CTCCTGCTGA TCAGGAAGTA CATCCCCCGA 600
AGATCTTTCT TCATTTCTCT GGGCCATGAT GAGGAGTCAT CAGGGACAGG GGCTCAGAGG 660
ATCTCAGCCC TGCTACAGTC AAGGGGCGTC CAGCTAGCCT TCATTGTGGA CGAGGGGGGC 720
TTCATCTTGG ATGATTTCAT TCCTAACTTC AAGAAGCCCA TCGCCTTGAT TGCAGTCTCA 780
GAGAAGGGTT CCATGAACCT CATGCTGCAA GTAAACATGA CTTCAGGCCA CTCTTCAGCT 840
CCTCCAAAGG AGACAAGCAT TGGCATCCTT GCAGCTGCTG TCAGCCGATT GGAGCAGACA 900
CCAATGCCTA TCATATTTGG AAGCGGGACA GTGGTGACTG TATTGCAGCA ACTGGCAAAT 960
GAGGTTTATG GAGAGAAATC CCTTAACCAA TGCAATAATC AGGACCACCA CGGCACTCAC 1020
CATATTCAAA GCAGGGGTCA AGTTCAATGT CATCCCCCCA GTGGCCCAGG CCACAGTCAA 1080
CTTCCGGATT CACCCTGGAC AGACAGTCCA AGAGGTCCTA GAACTCACGA AGAACATTGT 1140
GGCTGATAAC AGAGTCCAGT TCCATGTGTT GAGTGCCTTT GACCCCCTCC CCGTCAGCCC 1200
TTCTGATGAC AAGGCCTTGG GCTACCAGCT GCTCCGCCAG ACCGTACAGT CCGTCTTCCC 1260
GGAAGTCAAT ATTACTGCCC CAGTTACTTC TATTGGCAAC ACAGACAGCC GATTCTTTAC 1320
AAACCTCACC ACTGGCATCT ACAGGTTCTA CCCCATCTAC ATACAGCCTG AAGACTTCAA 1380
ACGCATCCAT GGAGTCAACG AGAAAATCTC AGTCCAAGCC TATGAGACCC AAGTGAAATT 1440
CATCTTTGAG TTGATTCAGA ATGCTGACAC AGACCAGGAG CCAGTTTCTC ACCTGCACAA 1500
ACTGTGAGGT CAAGGGGCCT GCTGGGTTAG GCATGCCCGA CCCCGGGACA GGACTAACCC 1560
AAGGGGGAAA GCTAGTGTTG ATGAAACTTT TGATCAAAAC CACATTGTAA AACATTGCCC 1620
ATCTGTCTTG CTCACTCTTA AACTCTCCCA AGAACAAGGC CGGGGTAAGG TAAAGTCAGC 1680
AGAAATCTGG CTTCTCCCTT CCTCCCGACA TCTGCATCCC TTGATCCACT GGCATTTGCT 1740
GCCCTCTTGT CCCTTATCTG TCTTATGCTG GTTATTTCAC TGCTTCACCT TCCAGGCTTG 1800
ACTTAACAAA TGTAGATTTG AGAAATCTCA ACCAGTTGTT ACCTGATAGG AGTCTTTAAT 1860
TTAGGGCACT CTTGCTGGGA TGCTTTCTCC AGAGCTTATA TATTTCTTCT TACTAGAACT 1920
TTCTTCCCCC TTTTATTCCC CTCTCTTCTT GGACTCATGA GCTGTCTCTT CATCTCTCCT 1980
CTCTCTCCTG CATCTCTCCC CTTACTCTTC AATTTATTCT ACTTCTGGAC CTGGACTTAC 2040
CCAAACTGTG ATACTACCAT AATTGTCACC ATAATCAGTC AAATAAAGTG ATCTGTGCAT 2100 c
Seq ID NO: 201 Protein sequence
Protein Accession #: BAB71368.1
60
120
Figure imgf001034_0002
180
RSFFISLGHD EESSGTGAQR ISALLQSRGV QLAFIVDEGG FILDDFIPNF KKPIALIAVS 240
EKGSMNLMLQ VNMTSGHSSA PPKETSIGIL AAAVSRLEQT PMPIIFGSGT WTVLQQLAN 300
EVYGEKSLNQ CNNQDHHGTH HIQSRGQVQC HPPSGPGHSQ LPDSPWTDSP RGPRTHEEHC 360 G
Seq ID NO: 202 DNA sequence
Nucleic Acid Accession #: NM_004217.1 Coding sequence: 58..1092
60
120
Figure imgf001034_0003
180
ATGAGCCGCT CCAATGTCCA GCCCACAGCT GCCCCTGGCC AGAAGGTGAT GGAGAATAGC 240
AGTGGGACAC CCGACATCTT AACGCGGCAC TTCACAATTG ATGACTTTGA GATTGGGCGT 300
CCTCTGGGCA AAGGCAAGTT TGGAAACGTG TACTTGGCTC GGGAGAAGAA AAGCCATTTC 360
ATCGTGGCGC TCAAGGTCCT CTTCAAGTCC CAGATAGAGA AGGAGGGCGT GGAGCATCAG 420
CTGCGCAGAG AGATCGAAAT CCAGGCCCAC CTGCACCATC CCAACATCCT GCGTCTCTAC 480
AACTATTTTT ATGACCGGAG GAGGATCTAC TTGATTCTAG AGTATGCCCC CCGCGGGGAG 540
CTCTACAAGG AGCTGCAGAA GAGCTGCACA TTTGACGAGC AGCGAACAGC CACGATCATG 600
GAGGAGTTGG CAGATGCTCT AATGTACTGC CATGGGAAGA AGGTGATTCA CAGAGACATA 660
AAGCCAGAAA ATCTGCTCTT AGGGCTCAAG GGAGAGCTGA AGATTGCTGA CTTCGGCTGG , 720
TCTGTGCATG CGCCCTCCCT GAGGAGGAAG ACAATGTGTG GCACCCTGGA CTACCTGCCC 780
CCAGAGATGA TTGAGGGGCG CATGCACAAT GAGAAGGTGG ATCTGTGGTG CATTGGAGTG 840
CTTTGCTATG AGCTGCTGGT GGGGAACCCA CCCTTTGAGA GTGCATCACA CAACGAGACC 900
TATCGCCGCA TCGTCAAGGT GGACCTAAAG TTCCCCGCTT CTGTGCCCAC GGGAGCCCAG 960
GACCTCATCT CCAAACTGCT CAGGCATAAC CCCTCGGAAC GGCTGCCCCT GGCCCAGGTC 1020 TCAGCCCACC CTTGGGTCCG GGCCAACTCT CGGAGGGTGC TGCCTCCCTC TGCCCTTCAA 1080
TCTGTCGCCT GATGGTCCCT GTCATTCACT CGGGTGCGTG TGTTTGTATG TCTGTGTATG 1140
TATAGGGGAA AGAAGGGATC CCTAACTGTT CCCTTATCTG TTTTCTACCT CCTCCTTTGT 1200 TTAATAAAGG CTGAAGCTTT TTGT
Seq ID NO: 203 Protein sequence Protein Accession ft: NP 004208
31
MAQKENSYPW PYGRQTAPSG LSTLPQRVLR KEPVTPSALV LMSRSNVQPT AAPGQKVMEN 60
SSGTPDILTR HFTIDDFEIG RPLGKGKFGN VYLAREKKSH FIVALKVLFK SQIEKEGVEH 120
QLRREIEIQA HLHHPNILRL YNYFYDRRRI YLILEYAPRG ELYKELQKSC TFDEQRTATI 180
MEELADALMY CHGKKVIHRD IKPENLLLGL KGELKIADFG WSVHAPSLRR KTMCGTLDYL 240
PPEMIEGRMH NEKVDLWCIG VLCYELLVGN PPFESASHNE TYRRIVKVDL KFPASVPTGA 300
QDLISKLLRH NPSERLPLAQ VSAHPWVRAN SRRVLPPSAL QSVA
Seq ID NO: 204 DNA sequence
Nucleic Acid Accession #: AK055663 Coding sequence: 38..1423
11 21 31 41 51
I I I I I
AGAACGGCTT CCGGCGGGAG CTGTGCAGCT CCTTATCATG GGGACAATTC ATCTCTTTCG 60
AAAACCACAA AGATCCTTTT TTGGCAAGTT GTTACGGGAA TTTAGACTTG TAGCAGCTGA 120
CCGAAGGTCC TGGAAGATAC TGCTCTTTGG TGTAATAAAC TTGATATGTA CTGGCTTCCT 180
GCTTATGTGG TGCAGTTCTA CTAATAGTAT AGCTTTAACT GCCTATACTT ACCTGACCAT 240
TTTTGATCTT TTTAGTTTAA TGACATGTTT AATAAGTTAC TGGGTAACAT TGAGGAAACC 300
TAGCCCTGTC TATTCATTTG GGTTTGAAAG ATTAGAAGTC CTGGCTGTAT TTGCCTCCAC 360
AGTCTTGGCA CAGTTGGGAG CTCTCTTTAT ATTAAAAGAA AGTGCAGAAC GCTTTTTGGA 420
ACAGCCCGAG ATACACACGG GAAGATTATT AGTTGGTACT TTTGTGGCTC TTTGTTTCAA 480
CCTGTTCACG ATGCTTTCTA TTCGGAATAA ACCTTTTGCT TATGTCTCAG AAGCTGCTAG 540
TACGAGCTGG CTTCAAGAGC ATGTTGCAGA TCTTAGTCGA AGCTTGTGTG GAATTATTCC 600
GGGACTTAGC AGTATCTTCC TTCCCCGAAT GAATCCATTT GTTTTGATTG ATCTTGCTGG 660
AGCATTTGCT CTTTGTATTA CATATATGCT CATTGAAATT AATAATTATT TTGCCGTAGA 720
CACTGCCTCT GCTATAGCTA TTGCCTTGAT GACATTTGGC ACTATGTATC CCATGAGTGT 780
GTACAGTGGG AAAGTCTTAC TCCAGACAAC ACCACCCCAT GTTATTGGTC AGTTGGACAA 840
ACTCATCAGA GAGGTATCTA CCTTAGATGG AGTTTTAGAA GTCCGAAATG AACATTTTTG 900
GACCCTAGGT TTTGGCTCAT TGGCTGGATC AGTGCATGTA AGAATTCGAC GAGATGCCAA 960
TGAACAAATG GTTCTTGCTC ATGTGACCAA CAGGCTGTAC ACTCTAGTGT CTACTCTAAC 1020
TGTTCAAATT TTCAAGGATG ACTGGATTAG GCCTGCCTTA TTGTCTGGGC CTGTTGCAGC 1080
CAATGTCCTA AACTTTTCAG ATCATCACGT AATCCCAATG CCTCTTTTAA AGGGTACTGA 1140
TGATTTGAAC CCAGTTACAT CAACTCCAGC TAAACCTAGT AGTCCACCTC CAGAATTTTC 1200
ATTTAACACT CCTGGGAAAA ATGTGAACCC AGTTATTCTT CTAAACACAC AAACAAGGCC 1260
TTATGGTTTT GGTCTCAATC ATGGACACAC ACCTTACAGC AGCATGCTTA ATCAAGGACT 1320
TGGAGTTCCA GGAATTGGAG CAACTCAAGG ATTGAGGACT GGTTTTACAA ATATACCAAG 1380
TAGATATGGA ACTAATAATA GAATTGGACA ACCAAGACCA TGATAGACTC TAACTTATTT 1440
TTATAAGGAA TATTGACTCC TTGGCTTCCA ATTTATTTAG TAATCCAACT TTGCATTGAC 1500
TGTTTAATCA TTTACTCTAA ATGTTAGATA ATAGTAGTCT TGTTCACATT TCATGAAACC 1560
TATGAAACTA TATTTTTGTA AAATGTATTT GTGACAGTGA AATCCTCGTA AATGTTAAAG 1620
GCTTTAAATA GGCTTCCTTT AGAAAATGTG TTTCTTTAAA TTTGGATTTT GGTATCTTTG 1680
GTTTTGTAGT TGACTGCAGT GTGATGTGAC CTTACCTTTA TAAGAGCCAC TTGATGGAGT 1740
AGATCTGTCA CATTACTAAG ATACGATATT TCCGAGACGG AGTCTTGCTC 1800
TGCCACTGTG CCCGGCCAAT ACATTATTAT TAACTTAAGG CTGTACTTTA TTAAGGCTTC 1860
CTTAGTTTTT GTTTTGTTTT GTTTTTTGAG ATGGAGTCTC ACTCTGTCGC CCAGGCTGGA 1920
ATGCAGTGGC ATGATCTCAG CTCACTGCAA CCTCTGCCTC CTGAGTTCAA ATGATTCTCC 1980
TGCCTCAGCC TCCCGAGTAG CTGGGATTAC AGGCACCTGC CACCACGCCC AGCTAATTTT 2040
TGTATTTTTA GTAAAGACGG GGGATTTCAC CATGTTGGCC AGGCTGGTCT TGAACTCCTG 2100
ACCTCATGAT CCACCCACCT TAGCCTCCCA AAGTGCTGGG ATTAGGTGTG AGCCACCGCA 2160
CCTGGCCGAT ATTTTCTTTA ATGAAATTTA TAAATATGCT TCTTGAATAA TACACATTTT 2220
GGGAAAGGGA AAAATGTCTG TTCAAAAAGT AAAGGTCTCT TTTATAGCTT TTCCAAACTT 2280
AATTGCTAAA TTTTTCTTTG AGGTTCTCCT GAATTATGTC TTACAAACTA AAAGCAAAAA 2340
TTTTTAGCAG AAATTTTGGA ATACATTCTA TCTAGCACAA TTTGAATTTT TAATTATCAA 2400
GATTTTTGTT AAAGTTTCTC TCCTTTAAAA ATTTTAGTAC ATTTGTAAAT
Seq ID NO: 205 Protein sequence Protein Accession it: BAB70980.1
11 21 31 41 51
I I I I I
MGTIHLFRKP QRSFFGKLLR EFRLVAADRR SWKILLFGVI NLICTGFLLM WCSSTNSIAL 60 TAYTYLTIFD LFSLMTCLIS YWVTLRKPSP VYSFGFERLE VLAVFASTVL AQLGALFILK 120 ESAERFLEQP EIHTGRLLVG TFVALCFNLF TMLSIRNKPF AYVSEAASTS WLQEHVADLS 180 RSLCGIIPGL SSIFLPRMNP FVLIDLAGAF ALCITYMLIE INNYFAVDTA SAIAIALMTF 240 GTMYPMSVYS GKVLLQTTPP HVIGQLDKLI REVSTLDGVL EVRNEHFWTL GFGSLAGSVH 300 VRIRRDANEQ MVLAHVTNRL YTLVSTLTVQ IFKDDWIRPA LLSGPVAANV LNFSDHHVIP 360 MPLLKGTDDL NPVTSTPAKP SSPPPEFSFN TPGKNVNPVI LLNTQTRPYG FGLNHGHTPY 420 SSMLNQGLGV PGIGATQGLR TGFTNIPSRY GTNNRIGQPR P
Seq ID NO: 206 DNA sequence
Nucleic Acid Accession ft: NM_016361.1
Coding sequence: 97..1662
11 21 31 51 I I I I I I
GGAACTCAGG GCCGGCTCCT GTTCCTTCAA GAGTGCTGGA GGCCAAACTT GAAATACAAG 60
TTTAATGTTC CTCGTCGGGC AAAAGATAAG GATCCGATCT CCCCCGGCCC GGTGTGCAGC 120
AGGAGCGACC AACCCCGACC CGGGTTAAAA CTCCCAGGGA CTCTTCGCTG CTGCCACCTC 180
TTGTTCTCTC CCCCGTTCCC ACTCGGGGTC TCCCTCAGGG CCGGGAGGCA CAGCGGTCCC 240
TGCTTGCTGA AGGGCTGGAT GTACGCATCC GCAGGTTCCC GCGGACTTGG GGGCGCCCGC 300
TGAGCCCCGG CGCCCGCAGA AGACTTGTGT TTGCCTCCTG CAGCCTCAAC CCGGAGGCAG 360
CGAGGGCCTA CCACCATGAT CACTGGTGTG TTCAGCATGC GCTTGTGGAC CCCAGTGGGC 420
GTCCTGACCT CGCTGGCGTA CTGCCTGCAC CAGCGGCGGG TGGCCCTGGC CGAGCTGCAG 480
GAGGCCGATG GCCAGTGTCC GGTCGACCGC AGCCTGCTGA AGTTGAAAAT GGTGCAGGTC 540
GTGTTTCGAC ACGGGGCTCG GAGTCCTCTC AAGCCGCTCC CGCTGGAGGA GCAGGTAGAG 600
TGGAACCCCC AGCTATTAGA GGTCCCACCC CAAACTCAGT TTGATTACAC AGTCACCAAT 660
CTAGCTGGTG GTCCGAAACC ATATTCTCCT TACGACTCTC AATACCATGA GACCACCCTG 720
AAGGGGGGCA TGTTTGCTGG GCAGCTGACC AAGGTGGGCA TGCAGCAAAT GTTTGCCTTG 780
GGAGAGAGAC TGAGGAAGAA CTATGTGGAA GACATTCCCT TTCTTTCACC AACCTTCAAC 840
CCACAGGAGG TCTTTATTCG TTCCACTAAC ATTTTTCGGA ATCTGGAGTC CACCCGTTGT 900
TTGCTGGCTG GGCTTTTCCA GTGTCAGAAA GAAGGACCCA TCATCATCCA CACTGATGAA 960
GCAGATTCAG AAGTCTTGTA TCCCAACTAC CAAAGCTGCT GGAGCCTGAG GCAGAGAACC 1020
AGAGGCCGGA GGCAGACTGC CTCTTTACAG CCAGGAATCT CAGAGGATTT GAAAAAGGTG 1080
AAGGACAGGA TGGGCATTGA CAGTAGTGAT AAAGTGGACT TCTTCATCCT CCTGGACAAC 1140
GTGGCTGCCG AGCAGGCACA CAACCTCCCA AGCTGCCCCA TGCTGAAGAG ATTTGCACGG 1200
ATGATCGAAC AGAGAGCTGT GGACACATCC TTGTACATAC TGCCCAAGGA AGACAGGGAA 1260
AGTCTTCAGA TGGCAGTAGG CCCATTCCTC CACATCCTAG AGAGCAACCT GCTGAAAGCC 1320
ATGGACTCTG CCACTGCCCC CGACAAGATC AGAAAGCTGT ATCTCTATGC GGCTCATGAT 1380
GTGACCTTCA TACCGCTCTT AATGACCCTG GGGATTTTTG ACCACAAATG GCCACCGTTT 1440
GCTGTTGACC TGACCATGGA ACTTTACCAG CACCTGGAAT CTAAGGAGTG GTTTGTGCAG 1500
CTCTATTACC ACGGGAAGGA GCAGGTGCCG AGAGGTTGCC CTGATGGGCT CTGCCCGCTG 1560
GACATGTTCT TGAATGCCAT GTCAGTTTAT ACCTTAAGCC CAGAAAAATA CCATGCACTC 1620
TGCTCTCAAA CTCAGGTGAT GGAAGTTGGA AATGAAGAGT AACTGATTTA TAAAAGCAGG 1680 ATGTGTTGAT TTTAAAATAA AGTGCCTTTA TACAAAAAAA AAAAAAAAAA A
Seq ID NO: 207 Protein sequence Protein Accession ft: NP_057445.1
1 11 21 31 41 51
I I I I I I
MRLWTPVGVL TSLAYCLHQR RVALAELQEA DGQCPVDRSL LKLKMVQWF RHGARSPLKP 60
LPLEEQVEWN PQLLEVPPQT QFDYTVTNLA GGPKPYSPYD SQYHETTLKG GMFAGQLTKV 120
GMQQMFALGE RLRKNYVEDI PFLSPTFNPQ EVFIRSTNIF RNLESTRCLL AGLFQCQKEG 180
PIIIHTDEAD SEVLYPNYQS CWSLRQRTRG RRQTASLQPG ISEDLKKVKD RMGIDSSDKV 240
DFFILLDNVA AEQAHNLPSC PMLKRFARMI EQRAVDTSLY ILPKEDRESL QMAVGPFLHI 300
LESNLLKAMD SATAPDKIRK LYLYAAHDVT FIPLLMTLGI FDHKWPPFAV DLTMELYQHL 360
ESKEWFVQLY YHGKEQVPRG CPDGLCPLDM FLNAMSVYTL SPEKYHALCS QTQVMEVGNE 420 E
Seq ID NO: 208 DNA sequence
Nucleic Acid Accession if: CAT cluster 1 11 21 31 41 51 I i i i i i
TTTGAGGGGG TGGTGGGGCG AGTTTAATTC ATAAAGAAGC CTCCTGATCA GAAAGGGGCC 60
TAACAGCCTG CCCTTGGAGA GAAGTCCTTC CTTGAGGATA AGGCCTCCCA GGGGAGGAGG 120
TGCTGGGGGC CAGTGTTAGG CTTCAGGCCA TCCCTGGAGG CCAGTCCTGT GCTCAGCAAG 180
TAGTGGCAGA GCCTGGAGTG ATGAGTGGGA TGGCCTTCTC AGGTACAGGA CTGTGCTGCT 240
TCTGGCTGCT CTTGCATTTG CATTTGCCAC TCAGAACTGC CGCGATCCCA GCAATGGCCA 300
GGAGCCCTCC GCAGATCAGT CCGCTCAGCT GCAGGTTTTT CCAGTCATAG TAGAAGGGAT 360
CGTCTTTATT GGCAAATGGG TCATTGGCTT CCAAGGCAGT CAGGCCAACT GTGTGACTCT 420
GCAGGTTCCT CACTGCTCCT TCACCAGTGT CCTGCGAGGT CACCTTGGCG AGGGCTCACC 480 TGAGCTGGCA GCGCAG
Seq ID NO: 209 DNA sequence
Nucleic Acid Accession #: FGENESH predicted
Coding sequence: 1..564
1 11 21 31 41 51
I I I I I I
ATGGAGCCCT GGGCGTGGCT GCAGGGTTTA AAGAGCCGAC CCACGTGCCC AGCAGCCTCC 60
TCAGATCCGT TCTCTGCGCT GCCAGCTCAG GACACTGGTG AAGGAGCAGT GAGGAACCTG 120
CAGAGTCACA CAGTTGGCCT GACTGCCTTG GAAGCCAATG ACCCATTTGC CAATAAAGAC 180
GATCCCTTCT ACTATGACTG GAAAAACCTG CAGCTGAGCG GACTGATCTG CGGAGGGCTC 240
CTGGCCATTG CTGGGATCGC GGCAGTTCTG AGTGGCAAAT GCAAATGCAA GAGCAGCCAG 300
AAGCAGCACA GTCCTGTACC TGAGAAGGCC ATCCCACTCA TCACTCCAGG CAGATTTCTC 360
ACCTTGGCCA AATCAAATAA ACCTTTATCT CCAAGCACCT TTGTCTTGGT GTTTGGCATC 420
AGCTACACAT CAGTCTTCCG AGTGCCTCTT TCTGCGTCCC TGTACCCTGC CATTCCTGGT 480
GATGCTGCTG CCCTCACATC AGGCCATCCA AGCATGCAGA ACATAAGCAT GCAGAACACT 540 GGAACGAAGG GCTGTACCTA ATGA
Seq ID NO: 210 Protein sequence Protein Acceεεion ft: FGENESH predicted
1 11 21 31 41 51
I I I I I I
MEPWAWLQGL KSRPTCPAAS SDPFSALPAQ DTGEGAVRNL QSHTVGLTAL EANDPFANKD 60
DPFYYDWKNL QLSGLICGGL LAIAGIAAVL SGKCKCKSSQ KQHSPVPEKA IPLITPGRFL 120 TLAKSNKPLS PSTFVLVFGI SYTSVFRVPL SASLYPAIPG DAAALTSGHP SMQNISMQNT 180 GTKGCT
Seq ID NO: 211 DNA εequence
Nucleic Acid Accession ft: FGENESH predicted
Coding sequence: 1..318
11 21 31 41 51
I I I I I
ATGCCCGGCC ACCCCGTCTG TGAAGTGAGG AGCACCTCTG CCCGGCTGCC CCGTCTGGGA 60 AGTGAGGAGC GCCTCTGCCC GGCTGCCACC CCGTCTGTGA GTGCCTGCTG CGCTGGGCCC 120 AGGCCGCCCG TGCCCTGCCA GGCCCTCCGG CCCCCCACCT TCCACCCCAG GGCCTGCTCC 180 TCACCCCAGG GTTCCATCTC CCTAGTTTCC ACCAGAGACT GGGTCTTCAT TCTCACCCTG 240 CTACACAGCC CCTACCAGAA CGTTCTGAAA TGCAAACCTA ACAACTGTCT CACCCCAGCA 300 GGAAACTCCC CAGGGTCCCG GGCCCCCTGC GGGGTTGCAG GCCTCACTCT TCGCGCCCAT 360 CCCTCCGCCC TGACCGCCCT GAGCTCGCCC CCAGTGCTGG CCCTTCACGT CCAGTTATCC 420 CTCCCAGCCT CCAAGGTCCC CGTTACCGAA GACCGCCACC ATCACGACAT AGCGCAGCAC 480 ATATGGGACA CTGGTGAAGG AGCAGTGAGG AACCTGCAGA GTCACACAGT TGGCCTGACT 540 GCCTTGGAAG CCAATGACCC ATTTGCCAAT AAAGACGATC CCTTCTACTA TGACTGGAAA 600 AACCTGCAGC TGAGCGGACT GATCTGCGGA GGGCTCCTGG CCATTGCTGG GATCGCGGCA 660 GTTCTGAGTG GCAAATGCAA ATGCAAGAGC AGCCAGAAGC AGCACAGTCC TGTACCTGAG 720 AAGGCCATCC CACTCATCAC TCCAGGCAGA TTTCTCACCT TGGCCAAATC AAATAAACCT 780 TTATCTCCAA GCACCTTTGT CTTGGTGTTT GGCATCAGCT ACACATCAGT CTTCCGAGTG 840 CCTCTTTCTG CGTCCCTGTA CCCTGCCATT CCTGGTGATG CTGCTGCCCT CACATCAGGC 900 CATCCAAGCA TGCAGAACAT AAGCATGCAG AACACTGGAA CGAAGGGCTG TACCTAA
Seq ID NO : 212 Protein sequence Protein Accesεion ft : FGENESH predicted
11 21 31 41 51
MPGHPVCEVR STSARLPRLG SEERLCPAAT PSVSACCAGP RPPVPCQALR PPTFHPRACS 60 SPQGSISLVS TRDWVFILTL LHSPYQNVLK CKPNNCLTPA GNSPGSRAPC GVAGLTLRAH 120 PSALTALSSP PVLALHVQLS LPASKVPVTE DRHHHDIAQH IWDTGEGAVR NLQSHTVGLT 180 ALEANDPFAN KDDPFYYDWK NLQLSGLICG GLLAIAGIAA VLSGKCKCKS SQKQHSPVPE 240 KAIPLITPGR FLTLAKSNKP LSPSTFVLVF GISYTSVFRV PLSASLYPAI PGDAAALTSG 300 HPSMQNISMQ NTGTKGCT
Seq ID NO : 213 DNA sequence Nucleic Acid Accession ft : FGENESH predicted
Coding sequence : 1 . .1758
11 21 31 41 51
I I I I I
ATGATGGGGT CTCATGTTGC CCAGGCTGGT CTTGAACTCC TGGGCTCGAG TGACCCTCCT 60 GCCTTGGCCT CCGAAAGTGC TGGGATTACA GGACTGTTAT TACAGGAATC CATAACACTG 120 GAGGATGTGG CTGTGGACTT CACTTGGGAG GAGTGGCAAC TCCTGGGCGC TGCTCAGAAG 180 GACCTGTACC GGGATGTGAT GTTGGAGAAC TACAGCAACC TGGTGGCAGT GGGGTATCAA 240 GCCAGCAAAC CGGATGCACT CTTCAAGTTG GAACAAGGAG AACAACTGTG GACAATTGAA 300 GATGGAATCC ACAGTGGAGC CTGTTCAGGT TCTCCAAAGG TCCCGTTCTC CATTTTCTCA 360 TCTGTGCCCT TCACTCTTCA AAATTGCCTT CATTCTAACA TATGGAAAGT TGATCATGTG 420 CTGGAGCGCT TGCAGAGTGA AAGCCTGGTG AACAGAAGGA AACCATGTCA TGAACATGAT 480 GCATTTGAAA ATATTGTTCA TTGCAGCAAA AGTCAGTTTC TGTTAGGGCA AAATCATGAT 540 ATATTTGACT TACGTGGAAA AAGTTTGAAA TCCAATTTAA CTTTAGTTAA CCAGAGCAAA 600 GGCTATGAAA TAAAGAACTC TGTTGAGTTT ACTGGAAATG GGGACTCCTT TCTTCATGCT 660 AACCATGAAC GACTTCATAC TGCAATTAAA TTCCCTGCAA GTCAAAAACT CATCAGCACT 720 AAGTCCCAAT TCATCAGTCC CAAGCATCAG AAAACACGAA AATTAGAGAA GCATCATGTG 780 TGCAGTGAAT GTGGGAAAGC CTTCATCAAG AAGTCTTGGC TAACTGATCA CCAGGTAATG 840 CATACAGGAG AGAAACCCCA CAGATGTAGT CTATGTGAGA AAGCCTTCTC CAGAAAGTTC 900 ATGCTTACTG AACATCAGCG AACTCATACA GGAGAAAAAC CTTATGAATG CCCTGAATGT 960 GGCAAAGCCT TTCTCAAGAA ATCACGGCTC AACATACATC AGAAAACACA TACCGGAGAG 1020 AAACCCTATA TATGCAGTGA ATGTGGAAAA GGCTTCATCC AGAAAGGAAA TCTCATTGTA 1080 CACCAGCGAA TTCATACAGG TGAGAAACCT TATATATGCA ATGAATGTGG AAAAGGCTTC 1140 ATTCAGAAGA CGTGTCTCAT AGCACATCAG AGATTTCACA CAGGAAAGAC GCCCTTTGTG 1200 TGCAGTGAAT GTGGAAAATC CTGTTCTCAG AAATCAGGTC TCATTAAACA TCAAAGAATT 1260 CACACAGGAG AGAAACCCTT TGAATGTAGT GAATGTGGGA AAGCCTTTAG CACAAAGCAA 1320 AAGCTCATTG TCCATCAAAG GACTCATACA GGAGAGAGAC CCTATGGCTG TAACGAGTGT 1380 GGGAAAGCGT TTGCGTATAT GTCGTGTCTG GTTAAGCATA AGAGAATACA CACAAGGGAG 1440 AAACAAGAGG CAGCCAAGGT GGAAAATCCT CCTGCAGAGA GGCACAGCTC ATTACACACC 1500 AGTGATGTCA TGCAGGAGAA AAACTCTGCT AACGGGGCGA CTACACAAGT GCCTTCTGTG 1560 GCCCCTCAGA CATCATTAAA CATCAGCGGC CTCCTCGCAA ACAGGAACGT AGTCCTTGTG 1620 GGACAGCCAG TGGTCAGATG TGCAGCCTCA GGAGATAACA GAGGATTTGC ACAGGACAGA 1680 AACCTTGTGA ATGCAGTGAA TGTGGTTGTG CCTTCCGTGA TCAATTATGT CTTATTTTAT 1740 GTTACAGAAA ACCCATAG
Seq ID NO: 214 Protein sequence Protein Accession if: FGENESH predicted 1 11 21 31 41 51 i i i i i i
MMGSHVAQAG LELLGSSDPP ALASESAGIT GLLLQESITL EDVAVDFTWE EWQLLGAAQK 60 DLYRDVMLEN YSNLVAVGYQ ASKPDALFKL EQGEQLWTIE DGIHSGACSG SPKVPFSIFS 120 SVPFTLQNCL HSNIWKVDHV LERLQSESLV NRRKPCHEHD AFENIVHCSK ΞQFLLGQNHD 180 IFDLRGKSLK SNLTLVNQSK GYEIKNSVEF TGNGDSFLHA NHERLHTAIK FPASQKLIST 240 KSQFISPKHQ KTRKLEKHHV CSECGKAFIK KSWLTDHQVM HTGEKPHRCS LCEKAFSRKF 300 MLTEHQRTHT GEKPYECPEC GKAFLKKSRL NIHQKTHTGE KPYICSECGK GFIQKGNLIV 360 HQRIHTGEKP YICNECGKGF IQKTCLIAHQ RFHTGKTPFV CSECGKSCSQ KSGLIKHQRI 420 HTGEKPFECS ECGKAFSTKQ KLIVHQRTHT GERPYGCNEC GKAFAYMSCL VKHKRIHTRE 480 KQEAAKVENP PAERHSSLHT SDVMQEKNSA NGATTQVPSV APQTSLNISG LLANRNWLV 540 GQPWRCAAS GDNRGFAQDR NLVNAVNVW PSVINYVLFY VTENP
Seq ID NO : 215 DNA sequence
Nucleic Acid Accession ft : NM_032190 . 1
Coding sequence : 502 . .1332
11 21 31
GATTCCGTGT TCTTGGCCAT GTTAGCCATA ATATCCTGTG CAGTATGTTT TTCCTGTGCA 60
GAGGCAAAAA CATATTGGGC ATATGTTCCC AAGCCCCCAG CAGTATGACC CATACTTTGG 120
AGTGACACTC CTCCTAAGAT TTATCATGAT TAAGGAGCAT GGGCTCCAGG ACCCCTAACT 180
CCACCTGACA TAGAACAGTT AGACTCTCAG AATAATGTCA TTAATTATAC CGCTCCATTG 240
GAAGGACTTC CTTTGTGTGT CACCACAAAG ACATCACTCA GCCATAGCTG TCTTACAGTT 300
CAAGCTCACA CATGGTTGAG TCACTATGGG AAAATCATGT ACTTATTAAG TCTTGGTTAT 360
ATTAATGTAA CCGGTGTGCT AACCAACCAT TCCTGGCCCA ATCGCCTTCA TTGTGCTGAC 420
TATACAGAAT GGATTCCCTT CAATAGTTCC TACCCCCCTC CATAGACCCA GTGTCTTGGC 480
CCACTGGCTA GAAAACAATC TATGTTAACT GGAGACATTG TGGATTGGGG ACCTAAAGGC 540
CAATTAGATG GAAAAGAAGA AAATCAGAAA TCGTGGCACA AACTTTGCTG GCATTGGTGG 600
CAAGCTTTTA ATGCTTCTTC TTTATATAAC ACTGGGATCC AATCCCAGTC GGCCGCCCAG 660
ATTGCTTGGC ATGGAGCAGG CTTTAGCCCG CCTCTTCCTC AGTGGCATTA TCTAGGGAGG 720
AAAGGACCAA TTCAAAAGAT GATATGGAAG GCAGCATTCC CATTTATGAA TGGCAACATC 780
TGGGTTGCCA TAATACTATC CAATAATAGC AATAGTAAGC AACACAGTCT TAATGTTACA 840
TTTGTAAAGA ATATCACCAC TCAATTTACA GTTTGTGTTT TTAATCCTTA TGTGTTTTTG 900
GCAGCTAAGA AGGACCAGCT CCAGGTAAAC AATACCCAAT TGACCTGTAA ATCTTGCCAG 960
TTATATCACT GCATTAATCA TAGCACATTG CAAACACATA ATATCTCTAC TTTGATGATT 1020
TTAGGTTGCA TCCCTGGGCT ATGGATTCCT GTTAATCTGT CTGAGCCATG GGCTGCCACA 1080
ATTGCTTTAC ATTTTGTGAA ACTTCTTCTA ACTCAGTTTA CTCATTGTGT CCGTAGAGGC 1140
TTAGGCATGA TAATTTTTGC TATTGTTTAC TTGGTCACAC TAATAATTTC TGTTGTGATG 1200
TCCTCTGTAG CTTTGCATAG TTCTATTCAA ACAGCTCAGT ATGTGGAGAA CTGGACACGC 1260
ACAGTCAACC AAGGGTGGCT ACTTGAGAAT AAAATTAACA CTGAGTTACA AACTGAAGTG 1320
GCAGTGTTAT AATCCACGAT TCTATGGTTA GGGGAACAAG TACAAAGCTT GCAATTGCAG 1380
CAGTAATTGT GTTGTCATTT TAATCACACT CATATTTGTG TAACCAACTT AGAATATAAC 1440
CAAAGTGAGT ATCCATGGGA TCTTGTGAAA GCCCATTTGC AGGGAGCTTT CACATCCGAC 1500
ATCACCTTTG ATATTGGTGA ATTAGAAAAC AAAATTCTTG ATTTAAATAA ACAAATTCCA 1560
GAGTTTCAGC CTTCTTTAGA AGACTGGACT GAATTCCAGC AAGGCCTGGA GAGCGTCAAC 1620
CCTTGGACCT ATCTAAAGCA CCACATTAAC ATCTTATATA TAGTTCTTGG AATAATGTTG 1680
TTTTGTCTCT GTCTTCTGTT CATAGTCTGT AAAATCGGAT GGACTGCCAA TCGGAGAATG 1740
AAAGCTACCC AGCCTGGCCT TACATTCTTT CACTTAATAC ATAAACAAGA AGGGGGAAAT 1800
GTTGGGAGCC AAAAAGGCCA AAGGGATGGT GACCAACTCA GCATTCCACT GGAGGCTACA 1860
TGATCAAACA GCAAACTGTT TATCATGAAT ACAGAATGTG GGCAAACTCG CTTCTGTGCC 1920
TGCCCAGAAG GTTTGCTGAG GGCCATCGCT CCCTGGCCCC GGCTCCTTGA GGTTATCTAC 1980
TGGGACATCT AGAGCCTATT GTTCGAGGAA TGCAGTCTTG CAAGCCTACT CTGGACCGAG 2040
CAGCTGACCT CTTCTTCCAC ACCCCTTCTC ACTATCTCTT TTGCCTAATA AATATGGAGG 2100
GCTGTGTAAA GCTCAGGGCC CTTGTCCACT AGAGGCAAGG TGTCCCCTGA CCCTTCTTCC 2160
AAACAT
Seq ID NO: 216 Protein sequence
Protein Accession # : : NP_115566.1
1 11 21 31 41 51 1 GDIVDWG P1KGQLDGKEE N1QKSWHKLCW H1WWQAFNASS L 1 1
MLT YNTGIQSQS AAQIAWHGAG 60
FSPPLPQWHY LGRKGPIQKM IWKAAFPFMN GNIWVAIILS NNSNSKQHSL NVTFVKNITT 120
QFTVCVFNPY VFLAAKKDQL QVNNTQLTCK SCQLYHCINH STLQTHNIST LMILGCIPGL 180
WIPVNLSEPW AATIALHFVK LLLTQFTHCV RRGLGMIIFA IVYLVTLIIS WMSSVALHS 240 SIQTAQYVEN WTRTVNQGWL LENKINTELQ TEVAVL
Seq ID NO : 217 DNA sequence Nucleic Acid Accession # : FGENESH predicted Coding sequence : 1 . . 1566
11 21 31 41 51
I I I I I
ATGGTGAACC CCAAATCCAC TTCCTCCCTC TTCAGGTTAT GTTTTTTGCT CCTGAGGAGT 60 CAGAACCTGT GGGTTGAAGA GCAAATTCAA TGCAAAAACA TATTGGGCAT ATGTTCCCAA 120 TCCCCCAGCA GTATGGCCTA TACTTTGGAG CTCACTCCTC CTGAGATTTA TCACGATCAG 180 GGAGAGTGGG CTCCAGGACC CCTAACTCCC CGTGACATAG AAAAGTTAGA CTCTCAGAAC 240 AATGTCATTA ATTATACCAC TCCACTGGAA GGACTCCCTT TGTTTATCAC CACAAAGACG 300 TCGCTCAGCC ATAGCTGTCT TGCAATTCAA GCTCAAACAT GGTTGAGTCA CTATGGAAAA 360 ATTATGTACT TATTAGGTCT TGGTTCTATT AATGTAACTG GTGTGCTAAC CAATCATTCC 420 CAGTCCAGTC ACCCTAATTG TGCTGATTAT ACAGAATGGA TTCCATTCAA TAGTTCCTAC 480 CCCACTCTGT GGACCCAGTG TCTTGATCCA CTGGCTAGTA AACAATATAT GTCAACTGAA 540 GACACTGTGG ATTGGGAACC TAAAGGTCAA TTAGATGGAA AAGGTGAAAG TCAGAAATCA 600 TGGCACAAAC TTCACTGGCA TTGGCGGCAA GCTTTTAATG CTTCTTCTTT ATACAACAGC 660 AGAATCCAAT CCCAGTCTGC TGCTCAGATT GCTTGGCATG GAGCAGGCTT TAGCCCACCT 720 CTTCCTCAGT TGCATTATCT GGGGAGGAAA GGACCAATTC AAGAAACTAT ATGGAAGGCA 780 GCACTCCCAT TTATGAATGG CAACATCTGG ATTGGAACAC TGTCTAATAA TAGCAATAGT 840 AAGCAACACA GTCTTAATGT TGCATTTGTA AAGAATATCA CCACTCAGTT TACAGTTTGT 900 GTTTTTAATC CTTATGCCTT TTTGGCAGCT AAGAAGAACC AGCTTCAGGT GGAGAACTGG 960 ACACGCACAG CTGACCAAGC GAGGCTACTT CAGAATAAAA TTAACACTGA GTTACAAACT 1020
GAAGTGGCAA TGTTGAAATC CATGGTTCTG TGGTTAGGAG AACAGGTACA AAGCTTGCAG 1080
TTGCAGCAGC AATTGCGTCA TCATTTTAAT CACATTCATA TTTGCGTAAC TAACTCAGAA 1140
TATAACCAAA GTGAGTATCC GTGGGACCTT GTGAAAGCCC ATTTGCAAGG AGCTTTCACA 1200
TCCAACATCA CCTTTGA AT TGGTGAATTA CAAAACAAAA TTATTGATTT AAATAGGCAA 1260
ACTCAAGAAT TTCAGCCTTC TTTAGAAGAC TGGACCGAAT TCCAGGAAGG CCTGGAGAGC 1320
CTCAACCCTT GGACCTATCT AAGGCACCAC ATTAACATCT TATATGTAGT TCTTGGAATA 1380
ATGTTGTTTT GTCTCTGTCT TCGGTTTATA GTCTGTAAAA TCGGATGGAC CACCAATTGG 1440
AGAATGAGAG CCTCCCAGCC CAGCCTTACA TTCTTTCAAT TAATACATAA ACAGAAAGGG 1500
GGATATGCAG GGAGCCAAAG GCCTGTGGGA CGTGACCAAC TCAGCATTCT GCTGGAGGCT 1560 ATATGA
Seq ID NO: 218 Protein sequence Protein Accesεion ft: FGENESH predicted
1 11 21 31 41 51
I I I I I I
MVNPKSTSSL FRLCFLLLRS QNLWVEEQIQ CKNILGICSQ SPSSMAYTLE LTPPEIYHDQ 60
GEWAPGPLTP RDIEKLDSQN NVINYTTPLE GLPLFITTKT SLSHSCLAIQ AQTWLSHYGK 120
IMYLLGLGSI NVTGVLTNHS QSSHPNCADY TEWIPFNSSY PTLWTQCLDP LASKQYMSTE 180
DTVDWEPKGQ LDGKGESQKS WHKLHWHWRQ AFNASSLYNS RIQSQSAAQI AWHGAGFSPP 240
LPQLHYLGRK GPIQETIWKA ALPFMNGNIW IGTLSNNSNS KQHSLNVAFV KNITTQFTVC 300
VFNPYAFLAA KKNQLQVENW TRTADQARLL QNKINTELQT EVAMLKSMVL WLGEQVQSLQ 360
LQQQLRHHFN HIHICVTNSE YNQSEYPWDL VKAHLQGAFT SNITFDIGEL QNKIIDLNRQ 420
TQEFQPSLED WTEFQEGLES LNPWTYLRHH INILYWLGI MLFCLCLRFI VCKIGWTTNW 480 RMRASQPSLT FFQLIHKQKG GYAGSQRPVG RDQLSILLEA I
Seq ID NO: 219 DNA sequence
Nucleic Acid Accession #: FGENESH predicted Coding sequence: 1..900
1 11 21 31 41 51
I I I I I I
ATGCCGCCGC GGGAGCTGAG CGAGGCCGAG CCGCCCCCGC TCCGGGCCCC GACCCCTCCC 60
CCGCGGCGGC GTAGCGCGCC CCCAGAGCTG GGCATCAAGT GCGTGCTGGT GGGCGACGGC 120
GCCGTGGGCA AGAGCAGCCT CATCGTCAGC TACACCTGCA ATGGGTACCC CGCGCGCTAC 180
CGGCCCACTG CGCTGGACAC CTTCTCTGGT ACGTACGTTC AATCGCCCGT GCGGCCGCGT 240
GGCTGCGGCG GGGCTGTGCA CCGGGGAGCT GGGGCGGGCG TCTCGGCGGG AGGGCGCAGA 300
GGACCCCGGG GAGGAGACTG GAGCAGGCCC CGAGGTGGCG CTGGTGCGGC CCAGGACGCT 360
CTTCCTAACT CAGGCTCTCC CCGCCCCGCC CCTGCAGTGC AAGTCCTGGT GGATGGAGCT 420
CCGGTGCGCA TTGAGCTCTG GGACACAGCG GGACAGGAGG ATTTTGACCG ACTTCGTTCC 480
CTTTGCTACC CGGATACCGA TGTCTTCCTG GCGTGCTTCA GCGTGGTGCA GCCCAGCTCC 540
TTTCAAAACA TCACAGAGAA ATGGCTGCCC GAGATCCGCA CGCACAACCC CCAGGCGCCT 600
GTGCTGCTGG TGGGCACCCA GGCCGACCTG AGGGACGATG TCAACGTACT AATTCAGCTG 660
GACCAGGGGG GCCGGGAGGG CCCCGTGCCC CAACCCCAGG CTCAGGGTCT GGCCGAGAAG 720
ATCCGAGCCT GCTGCTACCT TGAGTGCTCA GCCTTGACGC AGAAGAACTT GAAGGAAGTA 780
TTTGACTCGG CTATTCTCAG TGCCATTGAG CACAAAGCCC GGCTGGAGAA GAAACTGAAT 840 GCCAAAGGTG TGCGCACCCT CTCCCGCTGC CGCTGGAAGA AGTTCTTCTG CTTCGTTTGA Seq ID NO: 220 Protein sequence
Protein Accession ft: FGENESH predicted
1 11 21 31 41 51
I I I I I I
MPPRELSEAE PPPLRAPTPP PRRRSAPPEL GIKCVLVGDG AVGKSSLIVS YTCNGYPARY 60
RPTALDTFSG TYVQSPVRPR GCGGAVHRGA GAGVSAGGRR GPRGGDWSRP RGGAGAAQDA 120
LPNSGSPRPA PAVQVLVDGA PVRIELWDTA GQEDFDRLRS LCYPDTDVFL ACFSWQPSS 180
FQNITEKWLP EIRTHNPQAP VLLVGTQADL RDDVNVLIQL DQGGREGPVP QPQAQGLAEK 240 IRACCYLECS ALTQKNLKEV FDSAILSAIE HKARLEKKLN AKGVRTLSRC RWKKFFCFV
Seq ID NO: 221 DNA sequence
Nucleic Acid Accession ft: XM_063832.2
Coding sequence: 1..711
1 11 21 31 41 51
I I I I I I
ATGCCGCCGC GGGAGCTGAG CGAGGCCGAG CCGCCCCCGC TCCGGGCCCC GACCCCTCCC 60
CCGCGGCGGC GTAGCGCGCC CCCAGAGCTG GGCATCAAGT GCGTGCTGGT GGGCGACGGC 120
GCCGTGGGCA AGAGCAGCCT CATCGTCAGC TACACCTGCA ATGGGTACCC CGCGCGCTAC 180
CGGCCCACTG CGCTGGACAC CTTCTCTGTG CAAGTCCTGG TGGATGGAGC TCCGCTGCGC 240
ATTGAGCTCT GGGACACAGC GGGACAGGAG GATTTTGACC GACTTCGTTC CCTTTGCTAC 300
CCGGATACCG ATGTCTTCCT GGCGTGCTTC AGCGTGGTGC AGCCCAGCTC CTTTCAAAAC 360
ATCAGAGAGA AATGGCTGCC CGAGATCCGC ACGCACAACC CCCAGGCGCC TGTGCTGCTG 420
GTGGGCACCC AGGCCGACCT GAGGGACGAT GTCAACGTAC TAATTCAGCT GGACCAGGGG 480
GGCCGGGAGG GCCCCGTGCC CCAACCCCAG GCTCAGGGTC TGGCCGAGAA GATCCGAGCC 540
TGCTGCTACC TTGAGTGCTC AGCCTTGACG CAGAAGAACT TGAAGGAAGT ATTTGACTCG 600
GCTATTCTCA GTGCCATTGA GCACAAAGCC CGGCTGGAGA AGAAACTGAA TGCCAAAGGT 660 GTGCGCACCC TCTCCCGCTG CCGCTGGAAG AAGTTCTTCT GCTTCGTTTG A Seq ID NO: 222 Protein sequence Protein Accession #: XP 063832.1
41 MPPRELSEAE PPPLRAPTPP PRRRSAPPEL GIKCVLVGDG AVGKSSLIVS YTCNGYPARY 60
RPTALDTFSV QVLVDGAPVR IELWDTAGQE DFDRLRSLCY PDTDVFLACF SWQPSSFQN 120
ITEKWLPEIR THNPQAPVLL VGTQADLRDD VNVLIQLDQG GREGPVPQPQ AQGLAEKIRA 180 CCYLECSALT QKNLKEVFDS AILSAIEHKA RLEKKLNAKG VRTLSRCRWK KFFCFV
Seq ID NO: 223 DNA sequence
Nucleic Acid Accession #.- Eos sequence
Coding sequence: 1..1161
1 11 21 31 41 51
I I I I I I
ATGAATCGGC ACCATCTGCA GGATCACTTT CTGGAAATAG ACAAGAAGAA CTGCTGTGTG 60
TTCCGAGATG ACTTCATTGC CAAGGTGTTG CCGCCGGTGT TGGGGCTGGA GTTTATCTTT 120
GGGCTTCTGG GCAATGGCCT TGCCCTGTGG ATTTTCTGTT TCCACCTCAA GTCCTGGAAA 180
TCCAGCCGGA TTTTCCTGTT CAACCTGGCA GTAGCTGACT TTCTACTGAT CATCTGCCTG 240
CCGTTCGTGA TGGACTACTA TGTGCGGCGT TCAGACTGGA AGTTTGGGGA CATCCCTTGC 300
CGGCTGGTGC TCTTCATGTT TGCCATGAAC CGCCAGGGCA GCATCATCTT CCTCACGGTG 360
GTGGCGGTAG ACAGGTATTT CCGGGTGGTC CATCCCCACC ACGCCCTGAA CAAGATCTCC 420
AATTGGACAG CAGCCATCAT CTCTTGCCTT CTGTGGGGCA TCACTGTTGG CCTAACAGTC 480
CACCTCCTGA AGAAGAAGTT GCTGATCCAG AATGGCCCTG CAAATGTGTG CATCAGCTTC 540
AGCATCTGCC ATACCTTCCG GTGGCACGAA GCTATGTTCC TCCTGGAGTT CCTCCTGCCC 600
CTGGGCATCA TCCTGTTCTG CTCAGCCAGA ATTATCTGGA GCCTGCGGCA GAGACAAATG 660
GACCGGCATG CCAAGATCAA GAGAGCCATC ACCTTCATCA TGGTGGTGGC CATCGTCTTT 720
GTCATCTGCT TCCTTCCCAG CGTGGTTGTG CGGATCCGCA TCTTCTGGCT CCTGCACACT 780
TCGGGCACGC AGAATTGTGA AGTGTACCGC TCGGTGGACC TGGCGTTCTT TATCACTCTC 840
AGCTTCACCT ACATGAACAG CATGCTGGAC CCCGTGGTGT ACTACTTCTC CAGCCCATCC 900
TTTCCCAACT TCTTCTCCAC TTTGATCAAC CGCTGCCTCC AGAGGAAGAT GACAGGTGAG 960
CCAGATAATA ACCGCAGCAC GAGCGTCGAG CTCACAGGGG ACCCCAACAA AACCAGAGGC 1020
GCTCCAGAGG CGTTAATGGC CAACTCCGGT GAGCCATGGA GCCCCTCTTA TCTGGGCCCA 1080
ACCTCAAATA ACCATTCCAA GAAGGGACAT TGTCACCAAG AACCAGCATC TCTGGAGAAA 1140 CAGTTGGGAT GTTGCATCGA G
Seq ID NO: 224 Protein sequence Protein Accession it : Eos sequence
1 11 21 31 41 51
I I I I I I
MNRHHLQDHF LEIDKKNCCV FRDDFIAKVL PPVLGLEFIF GLLGNGLALW IFCFHLKSWK 60
SSRIFLFNLA VADFLLIICL PFVMDYYVRR SDWKFGDIPC RLVLFMFAMN RQGSIIFLTV 120
VAVDRYFRW HPHHALNKIS NWTAAIISCL LWGITVGLTV HLLKKKLLIQ NGPANVCISF 180
SICHTFRWHE AMFLLEFLLP LGIILFCSAR IIWSLRQRQM DRHAKIKRAI TFIMWAIVF 240
VICFLPSVW RIRIFWLLHT SGTQNCEVYR SVDLAFFITL SFTYMNSMLD PWYYFSSPS 300
FPNFFSTLIN RCLQRKMTGE PDNNRSTSVE LTGDPNKTRG APEALMANSG EPWSPSYLGP 360 TSNNHSKKGH CHQEPASLEK QLGCCIE
Seq ID NO: 225 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..1092
1 11 21 31 41 51
I I I I I I
ATGAATCGGC ACCATCTGCA GGATCACTTT CTGGAAATAG ACAAGAAGAA CTGCTGTGTG 60
TTCCGAGATG ACTTCATTGT CAAGGTGTTG CCGCCGGTGT TGGGGCTGGA GTTTATCTTC 120
GGGCTTCTGG GCAATGGCCT TGCCCTGTGG ATTTTCTGTT TCCACCTCAA GTCCTGGAAA 180
TCCAGCCGGA TTTTCCTGTT CAACCTGGCA GTGGCTGACT TTCTACTGAT CATCTGCCTG 240
CCCTTCCTGA TGGACAACTA TGTGAGGCGT TGGGACTGGA AGTTTGGGGA CATCCCTTGC 300
CGGCTGATGC TCTTCATGTT GGCTATGAAC CGCCAGGGCA GCATCATCTT CCTCACGGTG 360
GTGGCGGTAG ACAGGTATTT CCGGGTGGTC CATCCCCACC ACGCCCTGAA CAAGATCTCC 420
AATCGGACAG CAGCCATCAT CTCTTGCCTT CTGTGGGGCA TCACTATTGG CCTGACAGTC 480
CACCTCCTGA AGAAGAAGAT GCCGATCCAG AATGGCGGTG CAAATTTGTG CAGCAGCTTC 540
AGCATCTGCC ATACCTTCCA GTGGCACGAA GCCATGTTCC TCCTGGAGTT CTTCCTGCCC 600
CTGGGCATCA TCCTGTTCTG CTCAGCCAGA ATTATCTGGA GCCTGCGGCA GAGACAAATG 660
GACCGGCATG CCAAGATCAA GAGAGCCATC ACCTTCATCA TGGTGGTGGC CATCGTCTTT 720
GTCATCTGCT TCCTTCCCAG CGTGGTTGTG CGGATCCGCA TCTTCTGGCT CCTGCACACT 780
TCGGGCACGC AGAATTGTGA AGTGTACCGC TCGGTGGACC TGGCGTTCTT TATCACTCTC 840
AGCTTCACCT ACATGAACAG CATGCTGGAC CCCGTGGTGT ACTACTTCTC CAGCCCATCC 900
TTTCCCAACT TCTTCTCCAC TTTGATCAAC CGCTGCCTCC AGAGGAAGAT GACAGGTGAG 960
CCAGATAATA ACCGCAGCAC GAGCGTCGAG CTCACAGGGG ACCCCAACAA AACCAGAGGC 1020
GCTCCAGAGG CGTTAATGGC CAACTCCGGT GAGCCATGGA GCCCCTCTTA TCTGGGCCCA 1080
Seq ID NO: 226 Protein sequence Protein Accession # : Eos sequence
1 11 21 31 41 51
I I I I I I
MNRHHLQDHF LEIDKKNCCV FRDDFIVKVL PPVLGLEFIF GLLGNGLALW IFCFHLKSWK 60
SSRIFLFNLA VADFLLIICL PFLMDNYVRR WDWKFGDIPC RLMLFMLAMN RQGSIIFLTV 120
VAVDRYFRW HPHHALNKIS NRTAAIISCL LWGITIGLTV HLLKKKMPIQ NGGANLCSSF 180
SICHTFQWHE AMFLLEFFLP LGIILFCSAR IIWSLRQRQM DRHAKIKRAI TFIMWAIVF 240
VICFLPSVW RIRIFWLLHT SGTQNCEVYR SVDLAFFITL SFTYMNSMLD PWYYFSSPS 300
FPNFFSTLIN RCLQRKMTGE PDNNRSTSVE LTGDPNKTRG APEALMANSG EPWSPSYLGP 360 TSP Seq ID NO: 227 DNA sequence
Nucleic Acid Accession ft: NM_006018
Coding sequence: 61..1224
11 21 31 41 51
I I I I
CGCCACTTTG CTGGAGCATT CACTAGGCGA GGCGCTCCAT CGGACTCACT AGCCGCACTC 60 ATGAATCGGC ACCATCTGCA GGATCACTTT CTGGAAATAG ACAAGAAGAA CTGCTGTGTG 120 TTCCGAGATG ACTTCATTGC CAAGGTGTTG CCGCCGGTGT TGGGGCTGGA GTTTATCTTT 180 GGGCTTCTGG GCAATGGCCT TGCCCTGTGG ATTTTCTGTT TCCACCTCAA GTCCTGGAAA 240 TCCAGCCGGA TTTTCCTGTT CAACCTGGCA GTAGCTGACT TTCTACTGAT CATCTGCCTG 300 CCGTTCGTGA TGGACTACTA TGTGCGGCGT TCAGACTGGA ACTTTGGGGA CATCCCTTGC 360 CGGCTGGTGC TCTTCATGTT TGCCATGAAC CGCCAGGGCA GCATCATCTT CCTCACGGTG 420 GTGGCGGTAG ACAGGTATTT CCGGGTGGTC CATCCCCACC ACGCCCTGAA CAAGATCTCC 480 AATTGGACAG CAGCCATCAT CTCTTGCCTT CTGTGGGGCA TCACTGTTGG CCTAACAGTC 540 CACCTCCTGA AGAAGAAGTT GCTGATCCAG AATGGCCCTG CAAATGTGTG CATCAGCTTC 600 AGCATCTGCC ATACCTTCCG GTGGCACGAA GCTATGTTCC TCCTGGAGTT CCTCCTGCCC 660 CTGGGCATCA TCCTGTTCTG CTCAGCCAGA ATTATCTGGA GCCTGCGGCA GAGACAAATG 720 GACCGGCATG CCAAGATCAA GAGAGCCATC ACCTTCATCA TGGTGGTGGC CATCGTCTTT 780 GTCATCTGCT TCCTTCCCAG CGTGGTTGTG CGGATCCGCA TCTTCTGGCT CCTGCACACT 840 TCGGGCACGC AGAATTGTGA AGTGTACCGC TCGGTGGACC TGGCGTTCTT TATCACTCTC 900 AGCTTCACCT ACATGAACAG CATGCTGGAC CCCGTGGTGT ACTACTTCTC CAGCCCATCC 960 TTTCCCAACT TCTTCTCCAC TTTGATCAAC CGCTGCCTCC AGAGGAAGAT GACAGGTGAG 1020 CCAGATAATA ACCGCAGCAC GAGCGTCGAG CTCACAGGGG ACCCCAACAA AACCAGAGGC 1080 GCTCCAGAGG CGTTAATGGC CAACTCCGGT GAGCCATGGA GCCCCTCTTA TCTGGGCCCA 1140 ACCTCAAATA ACCATTCCAA GAAGGGACAT TGTCACCAAG AACCAGCATC TCTGGAGAAA 1200 CAGTTGGGCT GTTGCATCGA GTAATGTCAC TGGACTCGGC CTAAGGTTTC CTGGAACTTC 1260 CAGATTCAGA GAATCTGATT TAGGGAAACT GTGGCAGATG AGTGGGAGAC TGGTTGCAAG 1320 GTGTGACCAC AGGAATCCTG GAGGAACAGA GAGTAAAGCT TCTAGGCATC TGAAACTTGC 1380 TTCATCTCTG ACGCTCGCAG GACTGAAGAT GGGCAAATTG TAGGCGTTTC TGCTGAGCAG 1440 AGTTGGAGCC AGAGATCTAC TTGTGACTTG TTGGCCTTCT TCCCACATCT GCCTCAGACT 1500 GGGGGGGGCT CAGCTCCTCG GGTGATATCT AGCCTGCTTG TGAGCTCTAG CAGGGATAAG 1560 GAGAGCTGAG ATTGGAGGGA ATTGTGTTGC TCCTGGAGGA AGCCCAGGCA TCATTAAACA 1620 AGCCAGTAGG TCACCTGGCT TCCGTGGACC AATTCATCTT TCAGACAAGC TTTAGAGAAA 1680 TGGACTCAGG GAAGAGACTC ACATGCTTTG GTTAGTATCT GTGTTTCCGG TGGGTGTAAT 1740 AGGGGATTAG CCCCAGAAGG GACTGAGCTA AACAGTGTTA TTATGGGAAA GGAAATGGCA 1800 TTGCTGCTTT CAACCAGCGA CTAATGCAAT CCATTCCTCT CTTGTTTATA GTAATCTAAG 1860 GGTTGAGCAG TTAAAACGGC TTCAGGATAG AAAGCTGTTT CCCACCTGTT TCGTTTTACC 1920 ATTAAAAGGG AAACGTGCCT CTGCCCCACG GGTAGAGGGG GTGCACGTTC CTCCTGGTTC 1980 CTTCGCTTGT GTTTCTGTAC TTACCAAAAA TCTACCACTT CAATAAATTT TGATAGGAGA 2040 CAAAAAAAAA A
Seq ID NO: 228 Protein sequence Protein Accesεion #: NP 006009.1
11 21 31 41 51
MNRHHLQDHF LEIDKKNCCV FRDDFIAKVL PPVLGLEFIF GLLGNGLALW IFCFHLKSWK 60 SSRIFLFNLA VADFLLIICL PFVMDYYVRR SDWNFGDIPC RLVLFMFAMN RQGSIIFLTV 120 VAVDRYFRW HPHHALNKIS NWTAAIISCL LWGITVGLTV HLLKKKLLIQ NGPANVCISF 180 SICHTFRWHE AMFLLEFLLP LGIILFCSAR IIWSLRQRQM DRHAKIKRAI TFIMWAIVF 240 VICFLPSVW RIRIFWLLHT SGTQNCEVYR SVDLAFFITL SFTYMNSMLD PWYYFSSPS 300 FPNFFSTLIN RCLQRKMTGE PDNNRSTSVE LTGDPNKTRG APEALMANSG EPWSPSYLGP 360 TSNNHSKKGH CHQEPASLEK QLGCCIE
Seq ID NO: 229 DNA sequence
Nucleic Acid Accession ft: NM_014398.1
Coding sequence: 64..1314
11 21 31 51
GGCACCGATT CGGGGCCTGC CCGGACTTCG CCGCACGCTG CAGAACCTCG CCCAGCGCCC 60
ACCATGCCCC GGCAGCTCAG CGCGGCGGCC GCGCTCTTCG CGTCCCTGGC CGTAATTTTG 120
CACGATGGCA GTCAAATGAG AGCAAAAGCA TTTCCAGAAA CCAGAGATTA TTCTCAACCT 180
ACTGCAGCAG CAACAGTACA GGACATAAAA AAACCTGTCC AGCAACCAGC TAAGCAAGCA 240
CCTCACCAAA CTTTAGCAGC AAGATTCATG GATGGTCATA TCACCTTTCA AACAGCGGCC 300
ACAGTAAAAA TTCCAACAAC TACCCCAGCA ACTACAAAAA ACACTGCAAC CACCAGCCCA 360
ATTACCTACA CCCTGGTCAC AACCCAGGCC ACACCCAACA ACTCACACAC AGCTCCTCCA 420
GTTACTGAAG TTACAGTCGG CCCTAGCTTA GCCCCTTATT CACTGCCACC CACCATCACC 480
CCACCAGCTC ATACAGCTGG AACCAGTTCA TCAACCGTCA GCCACACAAC TGGGAACACC 540
ACTCAACCCA GTAACCAGAC CACCCTTCCA GCAACTTTAT CGATAGCACT GCACAAAAGC 600
ACAACCGGTC AGAAGCCTGA TCAACCCACC CATGCCCCAG GAACAACGGC AGCTGCCCAC 660
AATACCACCC GCACAGCTGC ACCTGCCTCC ACGGTTCCTG GGCCCACCCT TGCACCTCAG 720
CCATCGTCAG TCAAGACTGG AATTTATCAG GTTCTAAACG GAAGCAGACT CTGTATAAAA 780
GCAGAGATGG GGATACAGCT GATTGTTCAA GACAAGGAGT CGGTTTTTTC ACCTCGGAGA 840
TACTTCAACA TCGACCCCAA CGCAACGCAA GCCTCTGGGA ACTGTGGCAC CCGAAAATCC 900
AACCTTCTGT TGAATTTTCA GGGCGGATTT GTGAATCTCA CATTTACCAA GGATGAAGAA 960
TCATATTATA TCAGTGAAGT GGGAGCCTAT TTGACCGTCT CAGATCCAGA GACAGTTTAC 1020
CAAGGAATCA AACATGCGGT GGTGATGTTC CAGACAGCAG TCGGGCATTC CTTCAAGTGC 1080
GTGAGTGAAC AGAGCCTCCA GTTGTCAGCC CACCTGCAGG TGAAAACAAC CGATGTCCAA 1140
CTTCAAGCCT TTGATTTTGA AGATGACCAC TTTGGAAATG TGGATGAGTG CTCGTCTGAC 1200
TACACAATTG TGCTTCCTGT GATTGGGGCC ATCGTGGTTG GTCTCTGCCT TATGGGTATG 1260
GGTGTCTATA AAATCCGCCT AAGGTGTCAA TCATCTGGAT ACCAGAGAAT CTAATTGTTG 1320
CCCGGGGGGA ATGAAAATAA TGGAATTTAG AGAACTCTTT CATCCCTTCC AGGATGGATG 1380 TTGGGAAATT CCCTCAGAGT GTGGGTCCTT CAAACAATGT AAACCACCAT CTTCTATTCA 1440 AATGAAGTGA GTCATGTGTG ATTTAAGTTC AGGCAGCACA TCAATTTCTA AATACTTTTT 1500 GTTTATTTTA TGAAAGATAT AGTGAGCTGT TTATTTTCTA GTTTCCTTTA GAATATTTTA 1560 GCCACTCAAA GTCAACATTT GAGATATGTT GAATTAACAT AATATATGTA AAGTAGAATA 1620 AGCCTTCAAA TTATAAACCA AGGGTCAATT GTAACTAATA CTACTGTGTG TGCATTGAAG 1680 ATTTTATTTT ACCCTTGATC TTAACAAAGC CTTTGCTTTG TTATCAAATG GACTTTCAGT 1740 GCTTTTACTA TCTGTGTTTT ATGGTTTCAT GTAACATACA TATTCCTGGT GTAGCACTTA 1800 ACTCCTTTTC CACTTTAAAT TTGTTTTTGT TTTTTGAGAC GGAGTTTCAC TCTTGTCACC 1860 CAGGCTGGAG TACAGTGGCA CGATCTCGGC TTATGGCAAC CTCCGCCTCC CGGGTTCAAG 1920 TGATTCTCCT GCTTCAGCTT CCCGAGTAGC TGGGATTACA GGCACACACT ACCACGCCTG 1980 GCTAATTTTT GTATTTTTAT TATAGACGGG TTTCACCATG TTGGCCAGAC TGGTCTTGAA 2040 CTCTTGACCT CAGGTGATCC ACCCACCTCA GCCTCCCAAA GTGCTGGGAT TACAGGCATG 2100 AGCCATTGCG CCCGGCCTTA AATGTTTTTT TTAATCATCA AAAAGAACAA CATATCTCAG 2160 GTTGTCTAAG TGTTTTTATG TAAAACCAAC AAAAAGAACA AATCAGCTTA TATTTTTTAT 2220 CTTGATGACT CCTGCTCCAG AATTGCTAGA CTAAGAATTA GGTGGCTACA GATGGTAGAA 2280 CTAAACAATA AGCAAGAGAC AATAATAATG GCCCTTAATT ATTAACAAAG TGCCAGAGTC 2340 TAGGCTAAGC ACTTTATCTA TATCTCATTT CATTCTCACA ACTTATAAGT GAATGAGTAA 2400 ACTGAGACTT AAGGGAACTG AATCACTTAA ATGTCACCTG GCTAACTGAT GGCAGAGCCA 2460 GAGCTTGAAT TCATGTTGGT CTGACATCAA GGTCTTTGGT CTTCTCCCTA CACCAAGTTA 2520 CCTACAAGAA CAATGACACC ACACTCTGCC TGAAGGCTCA CACCTCATAC CAGCATACGC 2580 TCACCTTACA GGGAAATGGG TTTATCCAGG ATCATGAGAC ATTAGGGTAG ATGAAAGGAG 2640 AGCTTTGCAG ATAACAAAAT AGCCTATCCT TAATAAATCC TCCACTCTCT GGAAGGAGAC 2700 TGAGGGGCTT TGTAAAACAT TAGTCAGTTG CTCATTTTTA TGGGATTGCT TAGCTGGβCT 2760 GTAAAGATGA AGGCATCAAA TAAACTCAAA GTATTTTTAA ATTTTTTTGA TAATAGAGAA 2820 ACTTCGCTAA CCAACTGTTC TTTCTTGAGT GTATAGCCCC ATCTTGTGGT AACTTGCTGC 2880 TTCTGCACTT CATATCCATA TTTCCTATTG TTCACTTTAT TCTGTAGAGC AGCCTGCCAA 2940 GAATTTTATT TCTGCTGTTT TTTTTGCTGC TAAAGAAAGG AACTAAGTCA GGATGTTAAC 3000 AGAAAAGTCC ACATAACCCT AGAATTCTTA GTCAAGGAAT AATTCAAGTC AGCCTAGAGA 3060 CCATGTTGAC TTTCCTCATG TGTTTCCTTA TGACTCAGTA AGTTGGCAAG GTCCTGACTT 3120 TAGTCTTAAT AAAACATTGA ATTGTAGTAA AGGTTTTTGC AATAAAAACT TACTTTGG
Seq ID NO: 230 Protein sequence Protein Accession #: NP 055213.1
11 21 31 41 51
I I I I I
MPRQLSAAAA LFASLAVILH DGSQMRAKAF PETRDYSQPT AAATVQDIKK PVQQPAKQAP 60 HQTLAARFMD GHITFQTAAT VKIPTTTPAT TKNTATTSPI TYTLVTTQAT PNNΞHTAPPV 120 TEVTVGPSLA PYSLPPTITP PAHTAGTSSS TVSHTTGNTT QPSNQTTLPA TLSIALHKST 180 TGQKPDQPTH APGTTAAAHN TTRTAAPAST VPGPTIAPQP SSVKTGIYQV LNGSRLCIKA 240 EMGIQLIVQD KESVFSPRRY FNIDPNATQA SGNCGTRKSN LLLNFQGGFV NLTFTKDEES 300 YYISEVGAYL TVSDPETVYQ GIKHAWMFQ TAVGHSFKCV SEQSLQLSAH LQVKTTDVQL 360 QAFDFEDDHF GNVDECSSDY TIVLPVIGAI WGLCLMGMG VYKIRLRCQS SGYQRI
Seq ID NO: 231 DNA sequence
Nucleic Acid Accession it: NM_005409.3
Coding sequence: 94.-378
11 21 31 41 51
I I I I
TTCCTTTCAT GTTCAGCATT TCTACTCCTT CCAAGAAGAG CAGCAAAGCT GAAGTAGCAG 60 CAACAGCACC AGCAGCAACA GCAAAAAACA AACATGAGTG TGAAGGGCAT GGCTATAGCC 120 TTGGCTGTGA TATTGTGTGC TACAGTTGTT CAAGGCTTCC CCATGTTCAA AAGAGGACGC 180 TGTCTTTGCA TAGGCCCTGG GGTAAAAGCA GTGAAAGTGG CAGATATTGA GAAAGCCTCC 240 ATAATGTACC CAAGTAACAA CTGTGACAAA ATAGAAGTGA TTATTACCCT GAAAGAAAAT 300 AAAGGACAAC GATGCCTAAA TCCCAAATCG AAGCAAGCAA GGCTTATAAT CAAAAAAGTT 360 GAAAGAAAGA ATTTTTAAAA ATATCAAAAC ATATGAAGTC CTGGAAAAGG GCATCTGAAA 420 AACCTAGAAC AAGTTTAACT GTGACTACTG AAATGACAAG AATTCTACAG TAGGAAACTG 480 AGACTTTTCT ATGGTTTTGT GACTTTCAAC TTTTGTACAG TTATGTGAAG GATGAAAGGT 540 GGGTGAAAGG ACCAAAAACA GAAATACAGT CTTCCTGAAT GAATGACAAT CAGAATTCCA 600 CTGCCCAAAG GAGTCCAGCA ATTAAATGGA TTTCTAGGAA AAGCTACCTT AAGAAAβGCT 660 GGTTACCATC GGAGTTTACA AAGTGCTTTC ACGTTCTTAC TTGTTGTATT ATACATTCAT 720 GCATTTCTAG GCTAGAGAAC CTTCTAGATT TGATGCTTAC AACTATTCTG TTGTGACTAT 780 GAGAACATTT CTGTCTCTAG AAGTTATCTG TCTGTATTGA TCTTTATGCT ATATTACTAT 840 CTGTGGTTAC AGTGGAGACA TTGACATTAT TACTGGAGTC AAGCCCTTAT AAGTCAAAAG 900 CATCTATGTG TCGTAAAGCA TTCCTCAAAC ATTTTTTCAT GCAAATACAC ACTTCTTTCC 960 CCAAATATCA TGTAGCACAT CAATATGTAG GGAAACATTC TTATGCATCA TTTGGTTTGT 1020 TTTATAACCA ATTCATTAAA TGTAATTCAT AAAATGTACT ATGAAAAAAA TTATACGCTA 1080 TGGGATACTG GCAACAGTGC ACATATTTCA TAACCAAATT AGCAGCACCG GTCTTAATTT 1140 GATGTTTTTC AACTTTTATT CATTGAGATG TTTTGAAGCA ATTAGGATAT GTGTGTTTAC 1200 TGTACTTTTT GTTTTGATCC GTTTGTATAA ATGATAGCAA TATCTTGGAC ACATTTGAAA 1260 TACAAAATGT TTTTGTCTAC CAAAGAAAAA TGTTGAAAAA TAAGCAAATG TATACCTAGC 1320 AATCACTTTT ACTTTTTGTA ATTCTGTCTC TTAGAAAAAT ACATAATCTA ATCAATTTCT 1380 TTGTTCATGC CTATATACTG TAAAATTTAG GTATACTCAA GACTAGTTTA AAGAATCAAA 1440 GTCATTTTTT TCTCTAATAA ACTACCACAA CCTTTCTTTT TTAAAAAAAA AAA
Seq ID NO: 232 Protein sequence Protein Accession #: NP_005400.1
11 21 31 41 51
I I I I I I
MSVKGMAIAL AVILCATWQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF Seq ID NO: 233 DNA sequence
Nucleic Acid Accession ft: NM_000577.1
Coding sequence: 41..520
11 21 31 41 51
I I I I I
GGCACGAGGG GAAGACCTCC TGTCCTATCA GGCCCTCCCC ATGGCTTTAG AGACGATCTG 60 CCGACCCTCT GGGAGAAAAT CCAGCAAGAT GCAAGCCTTC AGAATCTGGG ATGTTAACCA 120 GAAGACCTTC TATCTGAGGA ACAACCAACT AGTTGCCGGA TACTTGCAAG GACCAAATGT 180 CAATTTAGAA GAAAAGATAG ATGTGGTACC CATTGAGCCT CATGCTCTGT TCTTGGGAAT 240 CCATGGAGGG AAGATGTGCC TGTCCTGTGT CAAGTCTGGT GATGAGACCA GACTCCAGCT 300 GGAGGCAGTT AACATCACTG ACCTGAGCGA GAACAGAAAG CAGGACAAGC GCTTCGCCTT 360 CATCCGCTCA GACAGTGGCC CCACCACCAG TTTTGAGTCT GCCGCCTGCC CCGGTTGGTT 420 CCTCTGCACA GCGATGGAAG CTGACCAGCC CGTCAGCCTC ACCAATATGC CTGACGAAGG 480 CGTCATGGTC ACCAAATTCT ACTTCCAGGA GGACGAGTAG TACTGCCCAG GCCTGCCTGT 540 TCCCATTCTT GCATGGCAAG GACTGCAGGG ACTGCCAGTC CCCCTGCCCC AGGGCTCCCG 600 GCTATGGGGG CACTGAGGAC CAGCCATTGA GGGGTGGACC CTCAGAAGGC GTCACAACAA 660 CCTGGTCACA GGACTCTGCC TCCTCTTCAA CTGACCAGCC TCCATGCTGC CTCCAGAATG 720 GTCTTTCTAA TGTGTGAATC AGAGCACAGC AGCCCCTGCA CAAAGCCCTT CCATGTCGCC 780 TCTGCATTCA GGATCAAACC CCGACCACCT GCCCAACCTG CTCTCCTCTT GCCACTGCCT 840 CTTCCTCCCT CATTCCACCT TCCCATGCCC TGGATCCATC AGGCCACTTG ATGACCCCCA 900 ACCAAGTGGC TCCCACACCC TGTTTTACAA AAAAGAAAAG ACCAGTCCAT GAGGGAGGTT 960 TTTAAGGGTT TGTGGAAAAT GAAAATTAGG ATTTCATGAT CAGTCCCCGT 1020 GAAGGAGAGC CCTTCATTTG GAGATTATGT TCTTTCGGGG AGAGGCTGAG GACTTAAAAT 1080 ATTCCTGCAT TTGTGAAATG ATGGTGAAAG TAAGTGGTAG CTTTTCCCTT CTTTTTCTTC 1140 TTTTTTTGTG ATGTCCCAAC TTGTAAAAAT TAAAAGTTAT GGTACTATGT TAGCCCCATA 1200 ATTTTTTTTT TCCTTTTAAA ACACTTCCAT AATCTGGACT CCTCTGTCCA GGCACTGCTG 1260 CCCAGCCTCC AAGCTCCATC TCCACTCCAG ATTTTTTACA GCTGCCTGCA GTACTTTACC 1320 TCCTATCAGA AGTTTCTCAG CTCCCAAGGC TCTGAGCAAA TGTGGCTCCT GGGGGTTCTT 1380 TCTTCCTCTG CTGAAGGAAT AAATTGCTCC TTGACATTGT AGAGCTTCTG GCACTTGGAG 1440 ACTTGTATGA AAGATGGCTG TGCCTCTGCC TGTCTCCCCC ACCAGGCTGG GAGCTGTGCA 1500 GAGCAGGAAA CATGACTCGT ATATGTCTCA GGTCCCTGCA GGGCCAAGCA CCTAGCCTCG 1560 CTCTTGGCAG GTACTCAGCG AATGAATGCT GTATATGTTG GGTGCAAAGT TCCCTACTTC 1620 CTGTGACTTC AGCTCTGTTT TACAATAAAA TCTTGAAAAT GCCTAAAAAA AAAAAAAAAA 1680 AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAA
Seq ID NO: 234 Protein sequence Protein Accession it: NP_000568.1
1 11 21 31 41 51
I I I I I I
MALETICRPS GRKSSKMQAF RIWDVNQKTF YLRNNQLVAG YLQGPNVNLE EKIDWPIEP 60 HALFLGIHGG KMCLSCVKSG DETRLQLEAV NITDLSENRK QDKRFAFIRS DSGPTTSFES 120 AACPGWFLCT AMEADQPVSL TNMPDEGVMV TKFYFQEDE
Seq ID NO: 235 DNA sequence
Nucleic Acid Accession #: NM_001840.1
Coding seguence: 149..1567
11 21 31 41 51
GGGGACTACG GAGAGCTCTG CAGGGAGCCG AGGCCCCCGC CCGGGCCAAG GGAGCTTCTG 60 TCCCGAGGAC CAGGGGATGC GAAGGGATTG CCCCCTGTGG GTCACTTTCT CAGTCATTTT 120 GAGCTCAGCC TAATCAAAGA CTGAGGTTAT GAAGTCGATC CTAGATGGCC TTGCAGATAC 180 CACCTTCCGC ACCATCACCA CTGACCTCCT GTACGTGGGC TCAAATGACA TTCAGTACGA 240 AGACATCAAA GGTGACATGG CATCCAAATT AGGGTACTTC CCACAGAAAT TCCCTTTAAC 300 TTCCTTTAGG GGAAGTCCCT TCCAAGAGAA GATGACTGCG GGAGACAACC CCCAGCTAGT 360 CCCAGCAGAC CAGGTGAACA TTACAGAATT TTACAACAAG TCTCTCTCGT CCTTCAAGGA 420 GAATGAGGAG AACATCCAGT GTGGGGAGAA CTTCATGGAC ATAGAGTGTT TCATGGTCCT 480 GAACCCCAGC CAGCAGCTGG CCATTGCAGT CCTGTCCCTC ACGCTGGGCA CCTTCACGGT 540 CCTGGAGAAC CTCCTGGTGC TGTGCGTCAT CCTCCACTCC CGCAGCCTCC GCTGCAGGCC 600 TTCCTACCAC TTCATCGGCA GCCTGGCGGT GGCAGACCTC CTGGGGAGTG TCATTTTTGT 660 CTACAGCTTC ATTGACTTCC ACGTGTTCCA CCGCAAAGAT AGCCGCAACG TGTTTCTGTT 720 CAAACTGGGT GGGGTCACGG CCTCCTTCAC TGCCTCCGTG GGCAGCCTGT TCCTCACAGC 780 CATCGACAGG TACATATCCA TTCACAGGCC CCTGGCCTAT AAGAGGATTG TCACCAGGCC 840 CAAGGCCGTG GTGGCGTTTT GCCTGATGTG GACCATAGCC ATTGTGATCG CCGTGCTGCC 900 TCTCCTGGGC TGGAACTGCG AGAAACTGCA ATCTGTTTGC TCAGACATTT TCCCACACAT 960 TGATGAAACC TACCTGATGT TCTGGATCGG GGTCACCAGC GTACTGCTTC TGTTCATCGT 1020 GTATGCGTAC ATGTATATTC TCTGGAAGGC TCACAGCCAC GCCGTCCGCA TGATTCAGCG 1080 TGGCACCCAG AAGAGCATCA TCATCCACAC GTCTGAGGAT GGGAAGGTAC AGGTGACCCG 1140 GCCAGACCAA GCCCGCATGG ACATTAGGTT AGCCAAGACC CTGGTCCTGA TCCTGGTGGT 1200 GTTGATCATC TGCTGGGGCC CTCTGCTTGC AATCATGGTG TATGATGTCT TTGGGAAGAT 1260 GAACAAGCTC ATTAAGACGG TGTTTGCATT CTGCAGTATG CTCTGCCTGC TGAACTCCAC 1320 CGTGAACCCC ATCATCTATG CTCTGAGGAG TAAGGACCTG CGACACGCTT TCCGGAGCAT 1380 GTTTCCCTCT TGTGAAGGCA CTGCGCAGCC TCTGGATAAC AGCATGGGGG ACTCGGACTG 1440 CCTGCACAAA CACGCAAACA ATGCAGCCAG TGTTCACAGG GCCGCAGAAA GCTGCATCAA 1500 GAGCACGGTC AAGATTGCCA AGGTAACCAT GTCTGTGTCC ACAGACACGT CTGCCGAGGC 1560 TCTGTGAGCC TGATGCCTCC CTGGCAGCAC AGGAAAAGAA TAAGCTCAAA 1620 ATCTAGAAGA GTCTATTGTC TCCTTGGTTA TATTTTTTTA ACTTTACCAT GCTCAATGAA 1680 AAGGTGATTG CCACATGTCA CTTATTTGCT TAGTTTCCGT TTGGGCTAAT CTTCCGGGGT 1740 TCGTAGGAAA CCTTT
Seq ID NO: 236 Protein sequence Protein Accession ft: NP 001831.1 11 21 31 41 51
I I I I I
MKSILDGLAD TTFRTITTDL LYVGSNDIQY EDIKGDMASK LGYFPQKFPL TSFRGSPFQE 60 KMTAGDNPQL VPADQVNITE FYNKSLSSFK ENEENIQCGE NFMDIECFMV LNPSQQLAIA 120 VLSLTLGTFT VLENLLVLCV ILHSRSLRCR PSYHFIGSLA VADLLGSVIF VYSFIDFHVF 180 HRKDSRNVFL FKLGGVTASF TASVGSLFLT AIDRYISIHR PLAYKRIVTR PKAWAFCLM 240 WTIAIVIAVL PLLGWNCEKL QSVCSDIFPH IDETYLMFWI GVTSVLLLFI VYAYMYILWK 300 AHSHAVRMIQ RGTQKSIIIH TSEDGKVQVT RPDQARMDIR LAKTLVLILV VLIICWGPLL 360 AIMVYDVFGK MNKLIKTVFA FCSMLCLLNS TVNPIIYALR SKDLRHAFRS MFPSCEGTAQ 420 PLDNSMGDΞD CLHKHANNAA SVHRAAESCI KSTVKIAKVT MSVSTDTSAE AL
Seq ID NO: 237 DNA sequence
Nucleic Acid Accession ft: NM_016083.2
Coding sequence: 64..1482
1 11 21 31 41 51
I I I I I I
GATTGCCCCC TGTGGGTCAC TTTCTCAGTC ATTTTGAGCT CAGCCTAATC AAAGACTGAG 60
GTTATGAAGT CGATCCTAGA TGGCCTTGCA GATACCACCT TCCGCACCAT CACCACTGAC 120
CTCCTGTACG TGGGCTCAAA TGACATTCAG TACGAAGACA TCAAAGGTGA CATGGCATCC 180
AAATTAGGGT ACTTCCCACA GAAATTCCCT TTAACTTCCT TTAGGGGAAG TCCCTTCCAA 240
GAGAAGATGA CTGCGGGAGA CAACCCCCAG CTAGTCCCAG CAGACCAGGT GAACATTACA 300
GAATTTTACA ACAAGTCTCT CTCGTCCTTC AAGGAGAATG AGGAGAACAT CCAGTGTGGG 360
GAGAACTTCA TGGACATAGA GTGTTTCATG GTCCTGAACC CCAGCCAGCA GCTGGCCATT 420
GCAGTCCTGT CCCTCACGCT GGGCACCTTC ACGGTCCTGG AGAACCTCCT GGTGCTGTGC 480
GTCATCCTCC ACTCCCGCAG CCTCCGCTGC AGGCCTTCCT ACCACTTCAT CGGCAGCCTG 540
GCGGTGGCAG ACCTCCTGGG GAGTGTCATT TTTGTCTACA GCTTCATTGA CTTCCACGTG 600
TTCCACCGCA AAGATAGCCG CAACGTGTTT CTGTTCAAAC TGGGTGGGGT CACGGCCTCC 660
CTCACTGCCT CCGTGGGCAG CCTGTTCCTC ACAGCCATCG ACAGGTACGT ATCCATTCAC 720
AGGCCCCTGG CCTATAAGAG GATTGTCACC AGGCCCAAGG CCGTGGTGGC GTTTTGCCTG 780
ATGTGGACCA TAGCCATTGC GATCGCCGTG CTGCCTCTCC TGGGCTGGAA CTGCGAGAAA 840
CTGCAATCTG TTTGCTCAGA CATTTTCCCA CACATTGATG AAACCTACCT GATGTTCTGG 900
ATCGGGGTCA CCAGCGTACT GCTTCTGTTC ATCGTGTATG CGTACATGTA TATTCTCTGG 960
AAGGCTCACA GCCACGCCGT CCGCATGATT CAGCGTGGCA CCCAGAAGAG CATCATCATC 1020
CACACGTCTG AGGATGGGAA GGTACAGGTG ACCCGGCCAG ACCAAGCCCG CATGGACATT 1080
AGGTTAGCCA AGACCCTGGT CCTGATCCTG GTGGTGTTGA TCATCTGCTG GGGCCCTTTG 1140
CTTGCAATCA TGGTGTATGA TGTCTTTGGG AAGATGAACA AGCTCATTAA GACGGTGTTT 1200
GCATTCTGCA GTATGCTCTG CCTGCTGAAC TCCACCGTGA ACCCCATCAT CTATGCTCTG 1260
AGGAGTAAGG ACCTGCGACA CGCTTTCCGG AGCATGTTTC CCTCTTGTGA AGGCACTGCG 1320
CAGCCTCTGG ATAACAGCAT GGGGGACTCG GACTGCCTGC ACAAACACGC AAACAATGCA 1380
GCCAGTGTTC ACAGGGCCGC AGAAAGCTGC ATCAAGAGCA CGGTCAAGAT TGCCAAGGTA 1440
ACCATGTCTG TGTCCACAGA CACGTCTGCC GAGGCTCTGT GAGCCTGATG CCTCCCTGGC 1500
AGCACAGGAA AAGAATTTTT TTTTTTAAGC TCAAAATCTA GAAGAGTCTA TTGTCTCCTT 1560
GGTTATATTT TTTTAACTTT ACCATGCTCA ATGAAAAGGT GATTGTCACC ATGATCACTT 1620
ATCAGTTTGC TAATGTTTCC ATAGTTTAGG TACTCAAACT CCATTCTCCA GGGGTTTACA 1680
GTGAAGAAAG CCTGTTGTTT AAGTGACTGA ACGATCCTTC AAAGTCTCAA TGAAATAGGA 1740
GGGAAACCTT TGGCTACACA ATTGGAAGTC TAAGAACCCA TGGAAAAATG CCATCAAATG 1800
AATAATGCCT TTGTAACCAC AACTTTCACT ATAATGTGAA ATGTAACTGT CCGTAGTATC 1860
AGAGATGTCC ATTTTTACAA GTTATAGTAC TAGAGATATT TTGTAAAATG TATTATGTCC 1920
TGTGAGATGT GTATCAGTGT TTATGTGCTA TTAATATTTG TTTAGTTCAG CAAAACTGAA 1980
AGGTAGACTT TTATGAGAAC AATGGACAAG CAGTGGATAC GTGTCAATGT GTGCACTTTT 2040
TTTCTATATT ATTGCCCATG ATATAACTTT AGAAATAAAC CTTAATATTT CTTCAAATAT 2100
CTCTATTTAA TTTTGACACT GAAATAACCG TAAAGGTTTA TTTTTCTGTT ACCTCAACAA 2160
GAAGAATTTG AAGACTTCAA AATATTGAGC AGAATTCATT CATACTTAAA AATTTATTAG 2220
CCCTGCATTT TCATAGGAAG ACACATTATC TTCTGGACTA TAGCTGTTCT AATGGATTAT 2280
AATCAGAATG GAAGAGAGAA AGCATATTGA CTTTTTTTGA GCGACATCTC TGACTTTCTT 2340
TAGTCTTTAG CTATTACTGG ATCTCTTAAG ACAGCATGTG TTAATCTTAA TGTATATCGT 2400
TATCACTGTG CAGTTGCTGT TTACTTGAAT AGTATTGTGT TCCTATATTC CAGGTTTAAG 2460
TAGATTTCAT GCCTGGGTGG CCAAACAACA GTCTTCATTT TTTTTAATTG AAAAGAAGTA 2520
GTGTCTGGAT CAGTAAAATT ATACTGTGTG TGAGTGTGAA TATAAATGTG TGTATGTGTG 2580
TTTCTGTCCG TAACTGTTAC AGTAATGTCA TAAAGTGAGA AAACTGTGAC CAACTATAAA 2640
CTTTTACCAC TTGCTGCACT CTTGCACATG GATTCAGTTT CTAAAATTGA GTTCTTCCTG 2700
TAATCTTGTT GATAAAAATA CTGACTCCAA CCATTCAAAA ATTTCACCCC ATCCCTCCTT 2760
AAGAGATTGG ATCAAGTATT ACTAAATTGA CCTTTAGGTA TTACACAAGA CCAGTGCTTA 2820
GCAAAAAATA ATGACAGGCA TCCAAGGAAG GGATGTATTT GTAGTGTTAT TGCCAGGAAA 2880
GGAGAGTACT TTGGTTTCTG AGCACCGAAT ATTGAGCAAT ATGTCAGTCA CTAAAAGGAA 2940
GACAGTTCTA CAGAAAAACA AATGGTAACA TTTTTCAATA GCGTGTGTAG ATAGTATGCA 3000
CTATATACAT CACGTTAAAG TAGGACTATC ACACCCAGCC CATGTGGCTA AAAAAGCTGA 3060
ATCAGACAGT GGATGAGACA CACAACGGCA GTGAAGAACC GATACACTTG GCATTGACGT 3120
CTAGCTATGC TGTATCTGTG CTTTGCCCAC ATGCCCTTGG TGACAGCTGA GCACCCAGCT 3180
CTGTCTTGGT AGGTTTGGGC TAAGGAACAA ATCTCTCCTT TGCTCGTGGT TAGCAAGATA 3240
CACTCAAGCA TGAAGATAAA CACAGCTGCT TTCTTCTTAC ACCCCGGTCT CATGCTCCTT 3300
AATGGCGCCA TGGGTGCTTG TTGGGCCTTT TTCCAGTAAG GAATGATATT GCTGAAGAAT 3360
CTACTTAACC CTGACAAATT TTAATTATAA TCTCTTCTTA TACAGATAAA ACATGACTCC 3420
TACAAGGCCC CAAGGTTTAC ATAGTCTGAA GTGAAGTACA GAGCTGGCAT CTATCTGGTG 3480
ATTTCTAGCT CTCGAGATAC CCAAGCAGCC TGATGGGGCA GTTCCCCTTC TTACGGTTCA 3540
CGCTCTAAGG CAGGATGTGG CTTATGAGAT ACTTTGCATT GTCTGTCTGC ACACCTTGAA 3600
TCTGCCTGCT GGCTCCCTTA CTTTACCTCT CTGTCATGTG CAGATGAAGG CTCAGGGTGC 3660
TAGAGGATTA GTAAGATCTC TTTCTAAAGA CAGGAGAGAT TATTTACAAG AAGAACTCAC 3720
CAGGGTTTAG TTTGCATTTA AGAATTGCCA GTCTTTTGTC CTGCATCATC TTGAACATTA 3780
ATCCACATGT TTCAGAGCTC ACCAGGCAGT ACCAATGCTC TTTTCACAGC TATGAAGAGC 3840
TAGAGAAATT CTTGTTATGG TAGAAAAATT TCACGGTTCA TTTTTGAAAC TGCATTTGTG 3900
CGTATGCAGT GTAGATTTTA TAGTGTGTTG TGCTTTCAAG ATCTAAATCA TATATAATAA 3960 ATTAAGGGAC AATGGGGCTG ACAGCACTAA ACTTGGTGCT TATTGATATT CTAAGAAATA 4020 TCTGTGAAAT ATCATCACGT ATGTTATACA ACCTTCATTT AAAAAGGTTT AAAACTAGTT 4080 AGATTCACTT TGACACTTTT CATATCATTT CTTAACCCAA GTGACGAAAA CATTGTCCCC 4140 AATGAATATA CTCATTAGAA TTACCATTTG TTAATATCAC TCATTAATTA ACCCCATAAT 4200 TAGATCCATT AATTTAAATG ATTTAAATTT AAGTAAGTTT TATAAGGTCT GACATCAGAG 4260 GTATCTTACT TTCCTCTGAG GATGATGTAC TTGCCCTGAC CATGCATTTT ACCATCACAC 4320 ATGTTCAGAA AGGGCCAAAT TCCCAACCTG CTCATTTTTT TTTTTATCAG AGTCATGATG 4380 AATCAGTCCT AGAATGTTTC ATTTGCACAA GTAGGGCTGC CTCCAAGAGG AACCTCTGAT 4440 TTATTTTGTA TGAAATATAT GTGAAAGGAT ATGAATCTGA GAGATGCTGT AGACATCTGT 4500 CCTACACTTG AGATGATTTC CAAGCCTCTC TGGCACTTTG AGTTAAGTCT ATCTGGTATT 4560 AAATGCCAAG GACCTTTTGC TGCCTAAATC CACTCTGCAG GAAATAGGCC CAACCACCAG 4620 ATGAGAATTA GGCCCTGGAT GAGTAGCGCT ATAGTTACTG TCCTGTTGAT TAATTTCTGC 4680 CATTTCATGT CCATAAAAGA GACCACCCAT ATCATGCACA CAATTAGATT TCTCACACTC 4740 TAACTGTATA TTTGTATGAT ATTTTAAAAT CTCCTAAATG CTGGGCAATG GCTATTAACA 4800 ATTAATTGTC TTGCACTGGC CTTCTGATGA AATGTTAACA ATGCCTATTG TAATATAGAA 4860 AAAAACATTC TATCTACTGA TTTGGGCTGA ATGTATGTAA ATAGGTTTCT AAAAAGTCAG 4920 ATGTTTGAGC AGTGGCCTAC AAATCAGTAA TTTTCGGGTG GGAGAGTTTC TTTACATTGC 4980 CGTGGCATCT TAAAAGCTAT CTTCATGTAA ATTGACTGTA CTAGGCCTAC TGGGGATCAG 5040 AGTTCCCAAG AAAGGAAACC TTTTCTTGTA TCTGGATTCA AATTTATTTC CAATGTTTCA 5100 AGCGGGAAAC ATGACTCTTT ATTGTCTGTA AATCTAACAT TATTACTTTT CCTCTTAGAA 5160 GAATATTGTA TTGTTAGATG TTTGTTGAGC TGGTAACATC GTTGCAACCA CTGCAATATC 5220 TTCGTTAGTA ATCTGTATAA TACTTTGTAT ACAAGTACTG GTAAGATTGT TATTAAATGT 5280 AGCTTCAGTC ATTAAATTAC TATAGCAAAG TAGTACTTCT TCTGTAATAT TTACAATGTA 5340 TTAAGCCCAC AGTATATTTT ATTTCAATGT AATTAAACTG TTAACTTATT CAAAGAGAAA 5400 ACATCTCATC ATGTCTATTG TCCAAAGTTA CCTGGAATCA AATAAAAATT CTAGATTACC 5460 ATGAAGAACA TA
Seq ID NO: 238 Protein sequence Protein Accession ft: NP_057167.1
11 21 31 41 51
I I I 1
MKSILDGLAD TTFRTITTDL LYVGSNDIQY E 1DIKGDMASK LGYFPQKFPL TSFRGSPFQE 60 KMTAGDNPQL VPADQVNITE FYNKSLSSFK ENEENIQCGE NFMDIECFMV LNPSQQLAIA 120 VLSLTLGTFT VLENLLVLCV ILHSRSLRCR PSYHFIGSLA VADLLGSVIF VYSFIDFHVF 180 HRKDSRNVFL FKLGGVTASL TASVGSLFLT AIDRYVSIHR PLAYKRIVTR PKAWAFCLM 240 WTIAIAIAVL PLLGWNCEKL QSVCSDIFPH IDETYLMFWI GVTSVLLLFI VYAYMYILWK 300 AHSHAVRMIQ RGTQKSIIIH TSEDGKVQVT RPDQARMDIR LAKTLVLILV VLIICWGPLL 360 AIMVYDVFGK MNKLIKTVFA FCSMLCLLNS TVNPIIYALR SKDLRHAFRS MFPSCEGTAQ 420 PLDNSMGDSD CLHKHANNAA SVHRAAESCI KSTVKIAKVT MSVSTDTSAE AL
Seq ID NO: 239 DNA sequence
Nucleic Acid Accession it: NM_033181.1
Coding sequence: 17..1252
11 21 31 41 51
I I I I I
ATGAAGTCGA TCCTAGATGG CCTTGCAGAT ACCAGCTTCC GCACCATCAC CACTGACCTC 60 CTGTACGTGG GCTCAAATGA CATTCAGTAC GAAGACATCA AAGGAGAATG AGGAGAACAT 120 CCAGTGTGGG GAGAACTTCA TGGACATAGA GTCTTTCATG GTCCTGAACC CCAGCCAGCA 180 GCTGGCCATT GCAGTCCTGT CCCTCACGCT GGGCACCTTC ACGGTCCTGG AGAACCTCCT 240 GGTGCTGTGC GTCATCCTCC ACTCCCGCAG CCTCCGCTGC AGGCCTTCCT ACCACTTCAT 300 CGGCAGCCTG GCGGTGGCAG ACCTCCTGGG GAGTGTCATT TTTGTCTACA GCTTCATTGA 360 CTTCCACGTG TTCCACCGCA AAGATAGCCG CAACGTGTTT CTGTTCAAAC TGGGTGGGGT 420 CACGGCCTCC TTCACTGCCT CCGTGGGCAG CCTGTTCCTC ACAGCCATCG ACAGGTACAT 480 ATCCATTCAC AGGCCCCTGG CCTATAAGAG GATTGTCACC AGGCCCAAGG CCGTGGTGGC 540 GTTTTGCCTG ATGTGGACCA TAGCCATTGT GATCGCCGTG CTGCCTCTCC TGGGCTGGAA 600 CTGCGAGAAA CTGCAATCTG TTTGCTCAGA CATTTTCCCA CACATTGATG AAACCTACCT 660 GATGTTCTGG ATCGGGGTCA CCAGCGTACT GCTTCTGTTC ATCGTGTATG CGTACATGTA 720 TATTCTCTGG AAGGCTCACA GCCACGCCGT CCGCATGATT CAGCGTGGCA CCCAGAAGAG 780 CATCATCATC CACACGTCTG AGGATGGGAA GGTACAGGTG ACCCGGCCAG ACCAAGCCCG 840 CATGGACATT AGGTTAGCCA AGACCCTGGT CCTGATCCTG GTGGTGTTGA TCATCTGCTG 900 GGGCCCTCTG CTTGCAATCA TGGTGTATGA TGTCTTTGGG AAGATGAACA AGCTCATTAA 960 GACGGTGTTT GCATTCTGCA GTATGCTCTG CCTGCTGAAC TCCACCGTGA ACCCCATCAT 1020 CTATGCTCTG AGGAGTAAGG ACCTGCGACA CGCTTTCCGG AGCATGTTTC CCTCTTGTGA 1080 AGGCACTGCG CAGCCTCTGG ATAACAGCAT GGGGGACTCG GACTGCCTGC ACAAACACGC 1140 AAACAATGCA GCCAGTGTTC ACAGGGCCGC AGAAAGCTGC ATCAAGAGCA CGGTCAAGAT 1200 TGCCAAGGTA ACCATGTCTG TGTCCACAGA CACGTCTGCC GAGGCTCTGT GA
Seq ID NO: 240 Protein sequence Protein Accession if: NP 149421.1
11 21 31 41 51
I I I I I
MALQIPPSAP SPLTSCTWAQ MTFSTKTSKE NEENIQCGEN FMDIECFMVL NPSQQLAIAV 60 LSLTLGTFTV LENLLVLCVI LHSRSLRCRP SYHFIGSLAV ADLLGSVIFV YSFIDFHVFH 120 RKDSRNVFLF KLGGVTASFT ASVGSLFLTA IDRYISIHRP LAYKRIVTRP KAWAFCLMW 180 TIAIVIAVLP LLGWNCEKLQ SVCSDIFPHI DETYLMFWIG VTSVLLLFIV YAYMYILWKA 240 HSHAVRMIQR GTQKSIIIHT SEDGKVQVTR PDQARMDIRL AKTLVLILW LIICWGPLLA 300 1MVYDVFGKM NKLIKTVFAF CSMLCLLNST VNPIIYALRS KDLRHAFRSM FPSCEGTAQP 360 LDNSMGDSDC LHKHANNAAS VHRAAESCIK STVKIAKVTM SVSTDTSAEA L
Seq ID NO: 241 DNA sequence
Nucleic Acid Accession ft: NM 003596. Coding sequence : 82 . .1194
11 21 31 41 51
GTAGACTGTC CATGGCCTGA ACATTTTCCG AAAATCATTT TGAGCAAAAT ATCTGTTTAA 60 TAACAAGATA ACCACATCAA GATGGTTGGA AAGCTGAAGC AGAACTTACT ATTGGCATGT 120 CTGGTGATTA GTTCTGTGAC TGTGTTTTAC CTGGGCCAGC ATGCCATGGA ATGCCATCAC 180 CGGATAGAGG AACGTAGCCA GCCAGTCAAA TTGGAGAGCA CAAGGACCAC TGTGAGAACT 240 GGCCTGGACC TCAAAGCCAA CAAAACCTTT GCCTATCACA AAGATATGCC TTTAATATTT 300 ATTGGRGGTG TGCCTCGGAG TGGAACCACA CTCATGAGGG CCATGCTGGA CGCACATCCT 360 GACATTCGCT GTGGAGAGGA AACCAGGGTC ATTCCCCGAA TCCTGGCCCT GAAGCAGATG 420 TGGTCACGGT CAAGTAAAGA GAAGATCCGC CTGGATGAGG CTGGTGTTAC TGATGAAGTG 480 CTGGATTCTG CCATGCAAGC CTTCTTACTA GAAATTATCG TTAAGCATGG GGAGCCAGCC 540 CCTTATTTAT GTAATAAAGA TCCTTTTGCC CTGAAATCTT TAACTTACCT TTCTAGGTTA 600 TTCCCCAATG CCAAATTTCT CCTGATGGTC CGAGATGGCC GGGCATCAGT ACATTCAATG 660 ATTTCTCGAA AAGTTACTAT AGCTGGATTT GATCTGAACA GCTATAGGGA CTGTTTGACA 720 AAGTGGAATC GTGCTATAGA GACCATGTAT AACCAGTGTA TGGAGGTTGG TTATAAAAAG 780 TGCATGTTGG TTCACTATGA ACAACTTGTC TTACATCCTG AACGGTGGAT GAGAACACTC 840 TTAAAGTTCC TCCAGATTCC ATGGAACCAC TCAGTATTGC ACCATGAAGA GATGATTGGG 900 AAAGCTGGGG GAGTGTCTCT GTCAAAAGTG GAGAGATCTA CAGACCAAGT AATCAAGCCA 960 GTCAATGTAG GAGCTCTATC AAAATGGGTT GGGAAGATAC CGCCAGATGT TTTACAAGAC 1020 ATGGCAGTGA TTGCTCCTAT GCTTGCCAAG CTTGGATATG ACCCATATGC CAACCCACCT 1080 AACTACGGAA AACCTGATCC CAAAATTATT GAAAACACTC GAAGGGTCTA TAAGGGAGAA 1140 TTCCAACTAC CTGACTTTCT TAAAGAAAAA CCACAGACTG AGCAAGTGGA GTAGCAGAAC 1200 CAGGAGCCTC TTCCATACAT GAGGAAAGAT TGCTGCCTTT TCAGCAGAAG GGAAATTCCT 1260 AGGATTGGCT GTCCCCTGCC AAGCTTGGTG GAGCGTCTGC ACCTTGGCTG CGCCGCCTGT 1320 GCATTTGCCA GTTTCCTCCC ACTGAGAGGA TGGAGGTGTC CGCACAGCTT TGGGCCTCGT 1380 GAGGGATCTG CCTCCTGAGC AAAGAGCTCT TGATCCCGAT TTCATGCACA GCCCTGCAGT 1440 AAGGAGCCCA GAAGGAACAT GTGTTTCCTG TTAAAACTCC TCTTGTTCTC TTTTCTTACA 1500 TTATGACGTT TGTTTTCAAG GAGAGGGTTT AAAAATGGGA TCCTGTAAGC AGACTTGGGC 1560 AGTCTCCTTT TGAAATAGGT TGTCTGTACA TGTTCTAATG TTTTGTAGAA CACGTGTGCC 1620 TGTTTAAGTG TATTGATGTG AATAATATTA AATATCCTAA TTATTTAATT CATTGTATTG 1680 TTTCTGAGAA GTTGGGAAAT TACCATTATA CATTTACAAC CTAATGACTT TTGTATTTTA 1740 TTTTTCAAAA TAAAAGCTTT CAATGTGA
Seq ID NO: 242 Protein sequence Protein Accession it: NP 003587.1
11 21 31 41 51
I I 1 I I
MVGKLKQNLL LACLVISSVT VFYLGQHAME CHHRIEERSQ PVKLESTRTT VRTGLDLKAN 60 KTFAYHKDMP LIFIGGVPRS GTTLMRAMLD AHPDIRCGEE TRVIPRILAL KQMWSRSSKE 120 KIRLDEAGVT DEVLDSAMQA FLLEIIVKHG EPAPYLCNKD PFALKSLTYL SRLFPNAKFL 180 LMVRDGRASV HSMISRKVTI AGFDLNSYRD CLTKWNRAIE TMYNQCMEVG YKKCMLVHYE 240 QLVLHPERWM RTLLKFLQIP WNHSVLHHEE MIGKAGGVSL SKVERSTDQV IKPVNVGALS 300 KWVGKIPPDV LQDMAVIAPM LAKLGYDPYA NPPNYGKPDP KIIENTRRVY KGEFQLPDFL 360 KEKPQTEQVE
Seq ID NO: 243 DNA sequence Nucleic Acid Accession it: NM_001492.3 Coding sequence: 1395..2513
11 21 31 41 51
I I I I I
ACGCGGGGCG CGCGGCTCCG TCGGCTACCG CGGGCGGGCG CAGGCGACGG GCACGGCGGG 60 CGAGCGGGCG GTATGGCGGC GGCGGGGCCC GCGGCGGGGC CGACGGGGCC CGAGCCCATG 120 CCGAGCTACG CGCAGCTAGT GCAGCGCGGC TGGGGCAGCG CGCTGGCGGC GGCGCGGGGC 180 TGCACGGACT GCGGCTGGGG GCTGGCGCGT CGCGGCCTGG CTGAGCACGC GCACCTGGCG 240 CCGCCCGAGC TGCTGCTGCT GGCGCTCGGC GCGCTGGGCT GGACCGCGCT GCGCTCCGCG 300 GCCACTGCGC GCCTCTTTCG GCCCCTGGCG AAGCGGTGCT GCCTCCAGCC CAGAGATGCC 360 GCCAAGATGC CCGAGAGCGC TTGGAAGTTT CTCTTCTACC TGGGCAGCTG GAGCTACAGT 420 GCCTACCTGC TGTTTGGCAC CGACTACCCC TTCTTCCATG ACCCACCATC TGTCTTCTAC 480 GACTGGACGC CGGGCATGGC AGTGCCACGG GACATTGCAG CCGCCTACCT GCTCCAGGGA 540 AGCTTCTATG GCCACTCCAT CTACGCTACG CTATACATGG ACACCTGGCG CAAGGACTCG 600 GTGGTCATGC TGCTCCACCA CGTGGTCACT CTCATCCTCA TCGTCTCCTC CTACGCCTTC 660 CGGTACCACA ATGTGGGCAT CCTTGTGCTC TTCCTGCACG ATATCAGTGA CGTGCAGCTT 720 GAGTTCACCA AGCTCAACAT TTACTTCAAG TCCCGCGGCG GCTCCTACCA TCGGCTGCAT 780 GCCTTGGCAG CAGACTTGGG CTGCCTCAGC TTCGGCTTCA GCTGGTTCTG GTTCCGCCTC 840 TACTGGTTCC CGCTCAAGGT CCTGTATGCC ACCAGTCACT GCAGTCTGCG CACGGTGCCT 900 GACATCCCCT TCTACTTCTT CTTCAATGCG CTCCTGCTGC TGCTCACCCT TATGAACCTC 960 TACTGGTTCC TGTACATCGT GGCGTTTGCA GCCAAGGTGT TGACAGGCCA GGTGCACGAG 1020 CTGAAGGACC TGCGGGAGTA TGACACAGCC GAGGCCCAGA GCCTGAAGCC CAGCAAAGCC 1080 GAGAAGCCAC TGAGGAACGG CCTGGTGAAG GACAAGCGCT TCTGAACCCC TCGGCCCCGC 1140 CCCCGTGGAC CCGGCCCCAC CCCGAATACC CCGGCCACGC TCCCCGTCCT TGGCCGCCCC 1200 TCCACCCCCT CCAACTCTGC TCCTCTAGGG CCGCCGCCAC CTCCCCTGGG ACCCCGCCCC 1260 CTCATCCTGC CTCCATTTCC CGGCCACGCC CCCCAGGACC CCTGCCCCTC CGGGGACACC 1320 GGCCCCGCCC TCAGCCCACT GGTCCCGGGC CGCCGCGGAC CCTGCGCACT CTCTGGTCAT 1380 CGCCTGGGAG GAAGATGCCA CCGCCGCAGC AAGGTCCCTG CGGCCACCAC CTCCTCCTCC 1440 TCCTGGCCCT GCTGCTGCCC TCGCTGCCCC TGACCCGCGC CCCCGTGCCC CCAGGCCCAG 1500 CCGCCGCCCT GCTCCAGGCT CTAGGACTGC GCGATGAGCC CCAGGGTGCC CCCAGGCTCC 1560 GGCCGGTTCC CCCGGTCATG TGGCGCCTGT TTCGACGCCG GGACCCCCAG GAGACCAGGT 1620 CTGGCTCGCG GCGGACGTCC CCAGGGGTCA CCCTGCAACC GTGCCACGTG GAGGAGCTGG 1680 GGGTCGCCGG AAACATCGTG CGCCACATCC CGGACCGCGG TGCGCCCACC CGGGCCTCGG 1740 AGCCTGTCTC GGCCGCGGGG CATTGCCCTG AGTGGACAGT CGTCTTCGAC CTGTCGGCTG 1800 TGGAACCCGC TGAGCGCCCG AGCCGGGCCC GCCTβGAGCT GCGTTTCGCG GCGGCGGCGG 1860 CGGCAGCCCC GGAGGGCGGC TGGGAGCTGA GCGTGGCGCA AGCGGGCCAG GGCGCGGGCG 1920 CGGACCCCGG GCCGGTGCTG CTCCGCCAGT TGGTGCCCGC CCTGGGGCCG CCAGTGCGCG 1980 CGGAGCTGCT GGGCGCCGCT TGGGCTCGCA ACGCCTCATG GCCGCGCAGC CTCCGCCTGG 2040 CGCTGGCGCT ACGCCCCCGG GCCCCTGCCG CCTGCGCGCG CCTGGCCGAG GCCTCGCTGC 2100 TGCTGGTGAC CCTCGACCCG CGCCTGTGCC ACCCCCTGGC CCGGCCGCGG CGCGACGCCG 2160 AACCCGTGTT GGGCGGCGGC CCCGGGGGCG CTTGTCGCGC GCGGCGGCTG TACGTGAGCT 2220 TCCGCGAGGT GGGCTGGCAC CGCTGGGTCA TCGCGCCGCG CGGCTTCCTG GCCAACTACT 2280 GCCAGGGTCA GTGCGCGCTG CCCGTCGCGC TGTCGGGGTC CGGGGGGCCG CCGGCGCTCA 2340 ACCACGCTGT GCTGCGCGCG CTCATGCACG CGGCCGCCCC GGGAGCCGCC GACCTGCCCT 2400 GCTGCGTGCC CGCGCGCCTG TCGCCCATCT CCGTGCTCTT CTTTGACAAC AGCGACAACG 2460 TGGTGCTGCG GCAGTATGAG GACATGGTGG TGGACGAGTG CGGCTGCCGC TAACCCGGGG 2520 CGGGCAGGGA CGCGGGCCCA ACAATAAATG CCGCGTGGTC TGCTC
Seq ID NO: 244 Protein sequence Protein Accession #: NP 001483.2
31 41
MPPPQQGPCG HHLLLLLALL LPSLPLTRAP VPPGPAAALL QALGLRDEPQ GAPRLRPVPP 60
VMWRLFRRRD PQETRSGSRR TSPGVTLQPC HVEELGVAGN IVRHIPDRGA PTRASEPVSA 120
AGHCPEWTW FDLSAVEPAE RPSRARLELR FAAAAAAAPE GGWELSVAQA GQGAGADPGP 180
VLLRQLVPAL GPPVRAELLG AAWARNASWP RSLRLALALR PRAPAACARL AEASLLLVTL 240
DPRLCHPLAR PRRDAEPVLG GGPGGACRAR RLYVSFREVG WHRWVIAPRG FLANYCQGQC 300
ALPVALSGSG GPPALNHAVL RALMHAAAPG AADLPCCVPA RLSPISVLFF DNSDNWLRQ 360
YEDMWDECG CR
Seq ID NO: 245 DNA sequence
Nucleic Acid Accesεion #: NM.021267.1 Coding sequence: 17..1125
11 21 31 41 51
I I I I
ACGCGGGGCG CGCGGCTCCG TCGGCTACCG CGGGCGGGCG CAGGCGACGG GCACGGCGGG 60
CGAGCGGGCG GTATGGCGGC GGCGGGGCCC GCGGCGGGGC CGACGGGGCC CGAGCCCATG 120
CCGAGCTACG CGCAGCTAGT GCAGCGCGGC TGGGGCAGCG CGCTGGCGGC GGCGCGGGGC 180
TGCACGGACT GCGGCTGGGG GCTGGCGCGT CGCGGCCTGG CTGAGCACGC GCACCTGGCG 240
CCGCCCGAGC TGCTGCTGCT GGCGCTCGGC GCGCTGGGCT GGACCGCGCT GCGCTCCGCG 300
GCCACTGCGC GCCTCTTTCG GCCCCTGGCG AAGCGGTGCT GCCTCCAGCC CAGAGATGCC 360
GCCAAGATGC CCGAGAGCGC TTGGAAGTTT CTCTTCTACC TGGGCAGCTG GAGCTACAGT 420
GCCTACCTGC TGTTTGGCAC CGACTACCCC TTCTTCCATG ACCCACCATC TGTCTTCTAC 480
GACTGGACGC CGGGCATGGC AGTGCCACGG GACATTGCAG CCGCCTACCT GCTCCAGGGA 540
AGCTTCTATG GCCACTCCAT CTACGCTACG CTATACATGG ACACCTGGCG CAAGGACTCG 600
GTGGTCATGC TGCTCCACCA CGTGGTCACT CTCATCCTCA TCGTCTCCTC CTACGCCTTC 660
CGGTACCACA ATGTGGGCAT CCTTGTGCTC TTCCTGCACG ATATCAGTGA CGTGCAGCTT 720
GAGTTCACCA AGCTCAACAT TTACTTCAAG TCCCGCGGCG GCTCCTACCA TCGGCTGCAT 780
GCCTTGGCAG CAGACTTGGG CTGCCTCAGC TTCβGCTTCA GCTGGTTCTG GTTCCGCCTC 840
TACTGGTTCC CGCTCAAGGT CCTGTATGCC ACCAGTCACT GCAGTCTGCG CACGGTGCCT 900
GACATCCCCT TCTACTTCTT CTTCAATGCG CTCCTGCTGC TGCTCACCCT TATGAACCTC 960
TACTGGTTCC TGTACATCGT GGCGTTTGCA GCCAAGGTGT TGACAGGCCA GGTGCACGAG 1020
CTGAAGGACC TGCGGGAGTA TGACACAGCC GAGGCCCAGA GCCTGAAGCC CAGCAAAGCC 1080
GAGAAGCCAC TGAGGAACGG CCTGGTGAAG GACAAGCGCT TCTGAACCCC TCGGCCCCGC 1140
CCCCGTGGAC CCGGCCCCAC CCCGAATACC CCGGCCACGC TCCCCGTCCT TGGCCGCCCC 1200
TCCACCCCCT CCAACTCTGC TCCTCTAGGG CCGCCGCCAC CTCCCCTGGG ACCCCGCCCC 1260
CTCATCCTGC CTCCATTTCC CGGCCACGCC CCCCAGGACC CCTGCCCCTC CGGGGACACC 1320
GGCCCCGCCC TCAGCCCACT GGTCCCGGGC CGCCGCGGAC CCTGCGCACT CTCTGGTCAT 1380
CGCCTGGGAG GAAGATGCCA CCGCCGCAGC AAGGTCCCTG CGGCCACCAC CTCCTCCTCC 1440
TCCTGGCCCT GCTGCTGCCC TCGCTGCCCC TGACCCGCGC CCCCGTGCCC CCAGGCCCAG 1500
CCGCCGCCCT GCTCCAGGCT CTAGGACTGC GCGATGAGCC CCAGGGTGCC CCCAGGCTCC 1560
GGCCGGTTCC CCCGGTCATG TGGCGCCTGT TTCGACGCCG GGACCCCCAG GAGACCAGGT 1620
CTGGCTCGCG GCGGACGTCC CCAGGGGTCA CCCTGCAACC GTGCCACGTG GAGGAGCTGG 1680
GGGTCGCCGG AAACATCGTG CGCCACATCC CGGACCGCGG TGCGCCCACC CGGGCCTCGG 1740
AGCCTGTCTC GGCCGCGGGG CATTGCCCTG AGTGGACAGT CGTCTTCGAC CTGTCGGCTG 1800
TGGAACCCGC TGAGCGCCCG AGCCGGGCCC GCCTGGAGCT GCGTTTCGCG GCGGCGGCGG 1860
CGGCAGCCCC GGAGGGCGGC TGGGAGCTGA GCGTGGCGCA AGCGGGCCAG GGCGCGGGCG 1920
CGGACCCCGG GCCGGTGCTG CTCCGCCAGT TGGTGCCCGC CCTGGGGCCG CCAGTGCGCG 1980
CGGAGCTGCT GGGCGCCGCT TGGGCTCGCA ACGCCTCATG GCCGCGCAGC CTCCGCCTGG 2040
CGCTGGCGCT ACGCCCCCGG GCCCCTGCCG CCTGCGCGCG CCTGGCCGAG GCCTCGCTGC 2100
TGCTGGTGAC CCTCGACCCG CGCCTGTGCC ACCCCCTGGC CCGGCCGCGG CGCGACGCCG 2160
AACCCGTGTT GGGGGGCGGC CCCGGGGGCG CTTGTCGCGC GCGGCGGCTG TACGTGAGCT 2220
TCCGCGAGGT GGGCTGGCAC CGCTGGGTCA TCGCGCCGCG CGGCTTCCTG GCCAACTACT 2280
GCCAGGGTCA GTGCGCGCTG CCCGTCGCGC TGTCGGGGTC CGGGGGGCCG CCGGCGCTCA 2340
ACCACGCTGT GCTGCGCGCG CTCATGCACG CGGCCGCCCC GGGAGCCGCC GACCTGCCCT 2400
GCTGCGTGCC CGCGCGCCTG TCGCCCATCT CCGTGCTCTT CTTTGACAAC AGCGACAACG 2460
TGGTGCTGCG GCAGTATGAG GACATGGTGG TGGACGAGTG CGGCTGCCGC TAACCCGGGG
Seq ID NO: 246 Protein sequence Protein Accession ft: NP_067090.1
1 11 21 31 41 51
I I I I I I
MAAAGPAAGP TGPEPMPSYA QLVQRGWGSA LAAARGCTDC GWGLARRGLA EHAHLAPPEL 60 LLLALGALGW TALRSAATAR LFRPLAKRCC LQPRDAAKMP ESAWKFLFYL GSWSYSAYLL 120 FGTDYPFFHD PPSVFYDWTP GMAVPRDIAA AYLLQGSFYG HSIYATLYMD TWRKDSWML 180 LHHWTLILI VSSYAFRYHN VGILVLFLHD ISDVQLEFTK LNIYFKSRGG SYHRLHALAA 240
DLGCLSFGFS WFWFRLYWFP LKVLYATSHC SLRTVPDIPF YFFFNALLLL LTLMNLYWFL 300 YIVAFAAKVL TGQVHELKDL REYDTAEAQS LKPSKAEKPL RNGLVKDKRF
Seq ID NO: 247 DNA sequence
Nucleic Acid Accession #: NM_002081.1
Coding sequence: 222..1898
1 11 21 31 41 51
I I I I I I
GGCTGCCCGA GCGAGCGTTC GGACCTCGCA CCCCGCGCGC CCCGCGCCGC CGCCGCCGCC 60
GGCTTTTGTT GTCTCCGCCT CCTCGGCCGC CGCCGCCTCT GGACCGCGAG CCGCGCGCGC 120
CGGGACCTTG GCTCTGCCCT TCGCGGGCGG GAACTGCGCA GGACCCGGCC AGGATCCGAG 180
AGAGGCGCGG GCGGGTGGCC GGGGGCGCCG CCGGCCCCGC CATGGAGCTC CGGGCCCGAG 240
GCTGGTGGCT GCTATGTGCG GCCGCAGCGC TGGTCGCCTG CGCCCGCGGG GACCCGGCCA 300
GCAAGAGCCG GAGCTGCGGG GAGGTCCGCC AGATCTACGG AGCCAAGGGC TTCAGCCTGA 360
GCGACGTGCC CCAGGCGGAG ATCTCGGGTG AGCACCTGCG GATCTGTCCC CAGGGCTACA 420
CCTGCTGCAC CAGCGAGATG GAGGAGAACC TGGCCAACCG CAGCCATGCC GAGCTGGAGA 480
CCGCGCTCCG GGACAGCAGC CGCGTCCTGC AGGCCATGCT TGCCACCCAG CTGCGCAGCT 540
TCGATGACCA CTTCCAGCAC CTGCTGAACG ACTCGGAGCG GACGCTGCAG GCCACCTTCC 600
CCGGCGCCTT CGGAGAGCTG TACACGCAGA ACGCGAGGGC CTTCCGGGAC CTGTACTCAG 660
AGCTGCGCCT GTACTACCGC GGTGCCAACC TGCACCTGGA GGAGACGCTG GCCGAGTTCT 720
GGGCCCGCCT GCTCGAGCGC CTCTTCAAGC AGCTGCACCC CCAGCTGCTG CTGCCTGATG 780
ACTACCTGGA CTGCCTGGGC AAGCAGGCCG AGGCGCTGCG GCCCTTCGGG GAGGCCCCGA 840
GAGAGCTGCG GCTGCGGGCC ACCCGTGCCT TCGTGGCTGC TCGCTCCTTT GTGCAGGGCC 900
TGGGCGTGGC CAGCGACGTG GTCCGGAAAG TGGCTCAGGT CCCCCTGGGC CCGGAGTGCT 960
CGAGAGCTGT CATGAAGCTG GTCTACTGTG CTCACTGCCT GGGAGTCCCC GGCGCCAGGC 1020
CCTGCCCTGA CTATTGCCGA AATGTGCTCA AGGGCTGCCT TGCCAACCAG GCCGACCTGG 1080
ACGCCGAGTG GAGGAACCTC CTGGACTCCA TGGTGCTCAT CACCGACAAG TTCTGGGGTA 1140
CATCGGGTGT GGAGAGTGTC ATCGGCAGCG TGCACACGTG GCTGGCGGAG GCCATCAACG 1200
CCCTCCAGGA CAACAGGGAC ACGCTCACGG CCAAGGTCAT CCAGGGCTGC GGGAACCCCA 1260
AGGTCAACCC CCAGGGCCCT GGGCCTGAGG AGAAGCGGCG CCGGGGCAAG CTGGCCCCGC 1320
GGGAGAGGCC ACCTTCAGGC ACGCTGGAGA AGCTGGTCTC TGAAGCCAAG GCCCAGCTCC 1380
GCGACGTCCA GGACTTCTGG ATCAGCCTCC CAGGGACACT GTGCAGTGAG AAGATGGCCC 1440
TGAGCACTGC CAGTGATGAC CGCTGCTGGA ACGGGATGGC CAGAGGCCGG TACCTCCCCG 1500
AGGTCATGGG TGACGGCCTG GCCAACCAGA TCAACAACCC CGAGGTGGAG GTGGACATCA 1560
CCAAGCCGGA CATGACCATC CGGCAGCAGA TCATGCAGCT GAAGATCATG ACCAACCGGC 1620
TGCGCAGCGC CTACAACGGC AACGACGTGG ACTTCCAGGA CGCCAGTGAC GACGGCAGCG 1680
GCTCGGGCAG CGGTGATGGC TGTCTGGATG ACCTCTGCGG CCGGAAGGTC AGCAGGAAGA 1740
GCTCCAGCTC CCGGACGCCC TTGACCCATG CCCTCCCAGG CCTGTCAGAG CAGGAAGGAC 1800
AGAAGACCTC GGCTGCCAGC TGCCCCCAGC CCCCGACCTT CCTCCTGCCC CTCCTCCTCT 1860
TCCTGGCCCT TACAGTAGCC AGGCCCCGGT GGCGGTAACT GCCCCAAGGC CCCAGGGACA 1920
GAGGCCAAGG ACTGACTTTG CCAAAAATAC AACACAGACG ATATTTAATT CACCTCAGCC 1980
TGGAGAGGCC TGGGGTGGGA CAGGGAGGGC CGGCGGCTCT GAGCAGGGGC AGGCGCAGAG 2040
GTCCCAGCCC CAGGCCTGGC CTCGCCTGCC TTTCTGCCTT TTAATTTTGT ATGAGGTCCT 2100
CAGGTCAGCT GGGAGCCAGT GTGCCCAAAA GCCATGTATT TCAGGGACCT CAGGGGCACC 2160
TCCGGCTGCC TAGCCCTCCC CCCAGCTCCC TGCACCGCCG CAGAAGCAGC CCCTCGAGGC 2220
CTACAGAGGA GGCCTCAAAG CAACCCGCTG GAGCCCACAG CGAGCCTGTG CCTTCCTCCC 2280
CGCCTCCTCC CACTGGGACT CCCAGCAGAG CCCACCAGCC AGCCCTGGCC CACCCCCCAG 2340
CCTCCAGAGA AGCCCCGCAC GGGCTGTCTG GGTGTCCGCC ATCCAGGGTC TGGCAGAGCC 2400
TCTGAGATGA TGCATGATGC CCTCCCCTCA GCGCAGGCTG CAGAGCCCGG CCCCACCTCC 2460
CTGCGCCCTT GAGGGGCCCC AGCGTCTGCA GGGTGACGCC TGAGACAGCA CCACTGCTGA 2520
GGAGTCTGAG GACTGTCCTC CCACAGACCC TGCAGTGAGG GGCCCTCCAT GCGCAGATGA 2580
GGGGCCACTG ACCCACCTGC GCTTCTGCTG GAGGAGGGGA AGCTGGGCCC AAAGGCCCAG 2640
GGAGGCAGCG TGGGCTCTGC CAATGTGGGC TGCCCCTCGC ACACAGGGCT CACAGGGCAG 2700
GCCTTGCTGG GGTCCAGGGC TGTTGGAGGA CCCCGAGGGC TGAGGAGCAG CCAGGACCCG 2760
CCTGCTCCCA TCCTCACCCA GATCAGGAAC CAGGGCCTCC CTGTTCACGG TGACACAGGT 2820
CAGGGCTCAG AGTGACCCTC GGCTGTCACC TGCTCACAGG GATGCTGGTG GCTGGTGAGA 2880
CCCCGCACTG CACACGGGAA TGCCTAGGTC CCTTCCCGAC CCAGCCAGCT GCACTGCAGG 2940
GCACGGGGAC CTGGATAGTT AAGGGCTTTT CCAAACATGC ATCCATTTAC TGACACTTCC 3000
TGTCCTTGTT CATGGAGAGC TGTTCGCTCC TCCCAGATGG CTTCGGAGGC CCGCAGGGCC 3060
CACCTTGGAC CCTGGTGACC TCCTGTCACT CACTGAGGCC ATCAGGGCCC TGCCCCAGGC 3120
CTGGACGGGC CCTCCTTCCC TCCTGTGCCC CAGCTGCCAG GTGGCCCTGG GGAGGGGTGG 3180
TGTGGTGTTG GGAAGGGGTC CTGCAGGGGG AGGAGGACTT GGAGGGTCTG GGGGCAGCTG 3240
TCCTGAACCG ACTGACCCTG AGGAGGCCGC TTAGTGCTGC TTTGCTTTTC ATCACCGTCC 3300
CGCACAGTGG ACGGAGGTCC CCGGTTGCTG GTCAGGTCCC CATGGCTTGT TCTCTGGAAC 3360
CTGACTTTAG ATGTTTTGGG ATCAGGAGCC CCCAACACAG GCAAGTCCAC CCCATAATAA 3420
CCCTGCCAGT GCCAGGGTGG GCTGGGGACT CTGGCACAGT GATGCCGGGC GCCAGGACAG 3480
CAGCACTCCC GCTGCACACA GACGGCCTAG GGGTGGCGCT CAGACCCCAC CCTACGCTCA 3540
TCTCTGGAAG GGGCAGCCCT GAGTGGTCAC TGGTCAGGGC AGTGGCCAAG CCTGCTGTGT 3600
CCTTCCTCCA CAAGGTCCCC CCACCGCTCA GTGTCAGCGG GTGACGTGTG TTCTTTTGAG 3660 TCCTTGTATG AATAAAAGGC TGGAAACCTA AA
Seq ID NO: 248 Protein sequence Protein Accession ft: NP 002072.1
1 11 21 31 41 51
I I I I I I
MELRARGWWL LCAAAALVAC ARGDPASKSR SCGEVRQIYG AKGFSLSDVP QAEISGEHLR 60 ICPQGYTCCT SEMEENLANR SHAELETALR DSSRVLQAML ATQLRSFDDH FQHLLNDSER 120
TLQATFPGAF GELYTQNARA FRDLYSELRL YYRGANLHLE ETLAEFWARL LERLFKQLHP 180
QLLLPDDYLD CLGKQAEALR PFGEAPRELR LRATRAFVAA RSFVQGLGVA SDWRKVAQV 240
PLGPECSRAV MKLVYCAHCL GVPGARPCPD YCRNVLKGCL ANQADLDAEW RNLLDSMVLI 300
TDKFWGTSGV ESVIGSVHTW LAEAINALQD NRDTLTAKVI QGCGNPKVNP QGPGPEEKRR 360 RGKLAPRERP PSGTLEKLVS EAKAQLRDVQ DFWISLPGTL CSEKMALSTA SDDRCWNGMA 420 RGRYLPEVMG DGLANQINNP EVEVDITKPD MTIRQQIMQL KIMTNRLRSA YNGNDVDFQD 480 ASDDGSGSGS
Seq ID NO: 249 DNA sequence
Nucleic Acid Accession #: NM_001492.3
Coding sequence: 8..1864
11 21 31 41 51
I I I I I
GAAGGCCATG GTCTCCCCAC GGATGTCCGG GCTCCTCTCC CAGACTGTGA TCCTAGCGCT 60 CATTTTCCTC CCCCAGACAC GGCCCGCTGG CGTCTTCGAG CTGCAGATCC ACTCTTTCGG 120 GCCGGGTCCA GGCCCTGGGG CCCCGCGGTC CCCCTGCAGC GCCCGGCTCC CCTGCCGCCT 180 CTTCTTCAGA GTCTGCCTGA AGCCTGGGCT CTCAGAGGAG GCCGCCGAGT CCCCGTGCGC 240 CCTGCGCGCG GCGCTGAGTG CGCGCGGACC GGTCTACACC GAGCAGCCCG GAGCGCCCGC 300 GCCTGATCTC CCACTGCCCG ACGGGCTCTT GCAGGTGCCC TTCCGGGACG CCTGGCCTGG 360 CACCTTCTCT TTCATCATCG AAACCTGGAG AGAGGAGTTA GGAGACCAGA TTGGAGGGCC 420 CGCCTGGAGC CTGCTGGCGC GCGTGGCTGG CAGGCGGCGC TTGGCAGCCG GAGGCCCGTG 480 GGCCCGGGAC ATTCAGCGCG CAGGCGCCTG GGAGCTGCGC TTCTCGTACC GCGCGCGCTG 540 CGAGCCGCCT GCCGTCGGGA CCGCGTGCAC GCGCCTCTGC CGTCCGCGCA GCGCCCCCTC 600 GCGGTGCGGT CCGGGACTGC GCCCCTGCGC ACCGCTCGAG GACGAATGTG AGGCGCCGCT 660 GGTGTGCCGA GCAGGCTGCA GCCCTGAGCA TGGCTTCTGT GAACAGCCCG GTGAATGCCG 720 ATGCCTAGAG GGCTGGACTG GACCCCTCTG CACGGTCCCT GTCTCCACCA GCAGCTGCCT 780 CAGCCCCAGG GGCCCGTCCT CTGCTACCAC CGGATGCCTT GTCCCTGGGC CTGGGCCCTG 840 TGACGGGAAC CCGTGTGCCA ATGGAGGCAG CTGTAGTGAG ACACCCAGGT CCTTTGAATG 900 CACCTGCCCG CGTGGGTTCT ACGGGCTGCG GTGTGAGGTG AGCGGGGTGA CATGTGCAGA 960 TGGACCCTGC TTCAACGGCG GCTTGTGTGT CGGGGGTGCA GACCCTGACT CTGCCTACAT 1020 CTGCCACTGC CCACCTGGTT TCCAAGGCTC CAACTGTGAG AAGAGGGTGG ACCGGTGCAG 1080 CCTGCAGCCA TGCCGCAATG GCGGACTCTG CCTGGACCTG GGCCACGCCC TGCGCTGCCG 1140 CTGCCGCGCC GGCTTCGCGG GTCCTCGCTG CGAGCACGAC CTGGACGACT GCGCGGGCCG 1200 CGCCTGCGCT AACGGCGGCA CGTGTGTGGA GGGCGGCGGC GCGCACCGCT GCTCCTGCGC 1260 GCTGGGCTTC GGCGGCCGCG ACTGCCGCGA GCGCGCGGAC CCGTGCGCCG CGCGCCCCTG 1320 TGCTCACGGC GGCCGCTGCT ACGCCCACTT CTCCGGCCTC GTCTGCGCTT GCGCTCCCGG 1380 CTACATGGGA GCGCGGTGTG AGTTCCCAGT GCACCCCGAC GGCGCAAGCG CCTTGCCCGC 1440 GGCCCCGCCG GGCCTCAGGC CCGGGGACCC TCAGCGCTAC CTTTTGCCTC CGGCTCTGGG 1500 ACTGCTCGTG GCCGCGGGCG TGGCCGGCGC TGCGCTCTTG CTGGTCCACG TGCGCCGCCG 1560 TGGCCACTCC CAGGATGCTG GGTCTCGCTT GCTGGCTGGG ACCCCGGAGC CGTCAGTCCA 1620 CGCACTCCCG GATGCACTCA ACAACCTAAG GACGCAGGAG GGTTCCGGGG ATGGTCCGAG 1680 CTCGTCCGTA GATTGGAATC GCCCTGAAGA TGTAGACCCT CAAGGGATTT ATGTCATATC 1740 TGCTCCTTCC ATCTACGCTC GGGAGGTAGC GACGCCCCTT TTCCCCCCGC TACACACTGG 1800 GCGCGCTGGG CAGAGGCAGC ACCTGCTTTT TCCCTACCCT TCCTCGATTC TGTCCGTGAA 1860 ATGAATTGGG TAGAGTCTCT GGAAGGTTTT AAGCCCATTT TCAGTTCTAA CTTACTTTCA
Seq ID NO: 250 Protein sequence Protem Accession #: NP 058637.1
11 21 31 41 51
I I I I I
MVSPRMSGLL SQTVILALIF LPQTRPAGVF ELQIHSFGPG PGPGAPRSPC SARLPCRLFF 60 RVCLKPGLSE EAAESPCALG AALSARGPVY TEQPGAPAPD LPLPDGLLQV PFRDAWPGTF 120 SFIIETWREE LGDQIGGPAW SLLARVAGRR RLAAGGPWAR DIQRAGAWEL RFSYRARCEP 180 PAVGTACTRL CRPRSAPSRC GPGLRPCAPL EDECEAPLVC RAGCSPEHGF CEQPGECRCL 240 EGWTGPLCTV PVSTSSCLSP RGPSSATTGC LVPβPGPCDG NPCANGGSCS ETPRSFECTC 300 PRGFYGLRCE VSGVTCADGP CFNGGLCVGG ADPDSAYICH CPPGFQGSNC EKRVDRCSLQ 360 PCRNGGLCLD LGHALRCRCR AGFAGPRCEH DLDDCAGRAC ANGGTCVEGG GAHRCSCALG 420 FGGRDCRERA DPCAARPCAH GGRCYAHFSG LVCACAPGYM GARCEFPVHP DGASALPAAP 480 PGLRPGDPQR YLLPPALGLL VAAGVAGAAL LLVHVRRRGH SQDAGSRLLA GTPEPSVHAL 540 PDALNNLRTQ EGSGDGPSSS VDWNRPEDVD PQGIYVISAP SIYAREVATP LFPPLHTGRA 600 GQRQHLLFPY PSSILSVK
Seq ID NO: 251 DNA sequence
Nucleic Acid Accession ft: CAT cluster
11 21 31 41 51
I I I I I
GAAATATAAC CATTGCAATT AGAAAATATC CAAAATAGCC TGTTATCTTC CACGTGGCCT 60 AGATTATTGA CAATCCCAAA TATACAATTT TTCTTTAAAA GTAGTACAAT TTCCTTTGTA 120 GCTTCAATTC CTTATATGAC TTCAGACTGG AGAAGCCTGT TAAACCACTG TTAGTTTCAG 180 TTAGAAAGTC TGAGAGACTT TATACATAAA TTCTCAATTT GGCTGCTGTA CACGTGCCAG 240 AGTTTTACTA CTGTAGTGAC CGTTGAGAAG ACCCTTGTTT ATTTACATTT GAAGCACTGT 300 TTGTGCAAAC AACCTTTCAT TGTTAAGTGC CTGTATTCCT TTCATTTACT TCATGTCCAG 360 GGGTGCTATT TACCTAGAAC CATTGTCTAC TACAATTAAC ATTTACATTA CAAAGTGTGT 420 GGTTTTCTTT TTCAAGGAGG TTCAATTAAG GCAATAAGAT GTTTGCTGGA GAAACCTATT 480 GTTTACTGAA AGCACTCAAT GAAGTCAAAT TACTGAAGCT TTTGCCTACA TCTTGGTCTT 540 TTATGTAAAT ATGTTAAATA TAACATCTAA GGAAAATAAA CAATATTATA ATTATGTGTT 600 TGCCATTGTC ATATCAAACT TGCTTTGTAT CATACTAATG TTACATAACT TATCGATCAA 660 TAAAAATACA TTTCAATGTT AAAAAAAAAA AAAAAAAA
Seq ID NO: 252 DNA sequence
Nucleic Acid Accession it: Eos sequence
1 11 21 31 41 51
I I I I I I
AGGTACTGCC AGAAAGGATC AGGACCTGGA GTCTGGCAAG AGGAAGACAG AGGCCTGTGT GGGAAGCGAG TTGTTATCTT TGGTTATCTA GCTGTATGAG TGTATTGGTC TTCATAAAGC 120
TAGATAACCG AAAGTAAAAA CTTCTTCAAG ATCGCCGGGG AGCGTGTGAG AATGAAAGAC 180
TACAGCCGAG AGACAGTAAA AACCAGAAAG GTCAGGAATA CTTATTGAAT CTAACTTTGT 240
TTTTGTTTTG TATGATTAAA GGTGGGATGA GAGAAAATTA AATGACACAC 300
ACATGCTAAA ATATCAAGGT TCCAGATATG TCTTGAGAGG GGTTGTTGCA GCTGCAAAGG 360
AGAAGTGTAT AGTGATAATG AGTAAAGATG CATGTGCAGT TTGTTCTATT TTAAGGCAAA 420
AGTTATATCA GGGATTTTTT TCTTAGAAAG GTGTTGCAGA GATGTCTGGT ACCTAGTTTA 480
AAAATGATTC CATAATATGT AGACTTGGGC AGTTCCTTTG GGAGGCACCT CCCTCTCAAA 540
ATTTGAAGAT TGTGCTTGGA AATTACTTTA CATGTATTTG GGCTGTATGT CAATTTGTAC 600
GAAATTAGAC TTTCAGAAAA GTTTATACTG GAAGGTTAAT AATTTGTATC TACTGAGGAC 660
TTAGAGCTAG CAGGCAAAAT GAAAAAAAAA AAAAAAAARG CAAGGGCTGA TTTTTATTCT 720
TCTATTCAAA ATACAAGGAC AGATGCTTCT CTGTTCCAAG AGGGTTTCCT TGAGGAAGCT 780
ACTGAAGCAG AAAGACATGA TGGAGACGAG ATCGCCTCCC CTCTTGTCAA AGTGTTAAAA 840
AAATGTTCTG TCTTACTCTG CGCCTAGCAT TGGAAATGAA AGTGACATTT ACGCCACAAC 900
CCACGTGTGC GCCTCCTCTC TTTTTGTTTA AGGATGATCA GGTCTATCCA GGAAACAGCT 960
CTGGCATCCC AAACTGAAAT AATTAGGACG TATATAGACC TGACAAAAAT GGAAAGGGGG 1020
TGGGGAATCT GAGGGTCTGT CTTGCCTAAT TGATTCCGCT AAACGGAATG CAGGAGATGT 1080
GAACGGCAGG ACGCTCCGAT TCCCACGCTC GGGGGCAAGT GATAAAGCGG GGCCGGGCAG 1140
CCTATGACAG ACAGCCCTGT TGGGGGGTGG GGGTATGAAA AAAACATCAA GTGCACACAC 1200
CATACTCATC TCCATCGCTT AAGAAAGTAA AGGCATTTCC CACCCACAGC CATCTGCAGC 1260
TTCCCAAATG GCAGCACCAA CTGGTCTGTA GCTGCTACAT AGTCTGCTTC TGTTAATTTT 1320
TTAACCACTG TTTAATCTGG CCATAATTAA GTTTGGCTTT CTTCGTTGTT TGAGATTTTC 1380
AGAATTCAAG GCAAGCTAGT AGAAAGCAAT TCCAAGAAAG TCCCATGACT GCCTGCCCCT 1440
AATGTCAAAA TCTCAGTCCA TGAGATTATG GCCTTGTGAC CACATTTTTG CTTTTGTTTT 1500
GGGTGGGCAA ATGTGTATAG AGATAAAATA CATATCTCTA TATAACAGTC GTTATTATAA 1560
TTTCATGAGG CTTTTTACCT CTTAACATGA TACATCTAGG AACTTGGTCT AATTGTGCTA 1620
GTAGATATAC ACTAGAAGTA AAACTATAAA GTCATTAGCC TGTAGAAAGT TGATTATGAT 1680
AACAATATGA TAAAAAGTTT GTTTTGGAAT AGTCTCAGCT AGATGGGTCT AAATAGCCAT 1740
TTTAATGTAA TCTAAAAATA ACACTATGCC TAGCAGAAAC TTTGGCGCTT TGCAGGTCCC 1800
CATTGTCGCC TTTTCATAAA AGTCCTTAAG TTTTCCATAT GTCACCAAGC AAACATTTGT 1860
ATAGGCATTT ACACAGAAAT ATAACCATTG CAATTAGAAA ATATCCAAAA TAGCCTGTTA 1920
TCTTCCACGT GGCCTAGATT ATTGACAATC CCAAATATAC AATTTTTCTT TAAAAGTAGT 1980
ACAATTTCCT TTGTAGCTTC AATTCCTTAT ATGACTTCAG ACTGGAGAAG CCTGTTAAAC 2040
CACTGTTAGT TTCAGTTAGA AAGTCTGAGA GACTTTATAC ATAAATTCTC AATTTGGCTG 2100
CTGTACACGT GCCAGAGTTT TACTACTGTA GTGACCGTTG AGAAGACCCT TGTTTATTTA 2160
CATTTGAAGC ACTGTTTGTG CAAACAACCT TTCATTGTTA AGTGCCTGTA TTCCTTTCAT 2220
TTACTTCATG TCCAGGGGTG CTATTTACCT AGAACCATTG TCTACTACAA TTAACATTTA 2280
CATTACAAAG TGTGTGGTTT TCTTTTTCAA GGAGGTTCAA TTAAGGCAAT AAGATGTTTG 2340
CTGGAGAAAC CTATTGTTTA CTGAAAGCAC TCAATGAAGT CAAATTACTG AAGCTTTTGC 2400
CTACATCTTG GTCTTTTATG TAAATATGTT AAATATAACA TCTAAGGAAA ATAAACAATA 2460
TTATAATTAT GTGTTTGCCA TTGTCATATC AAACTTGCTT TGTATCATAC TAATGTTACA 2520
TAACTTATCG ATCAATAAAA ATACATTTCA ATGTT
Seq ID NO: 253 DNA sequence Nucleic Acid Accession ft: NM_001650.2 Coding sequence: 40.1011
11 21 31 41 51
I I I I I
GGGGCAGGCA ATGAGAGCTG CACTCTGGCT GGGGAAGGCA TGAGTGACAG ACCCACAGCA 60 AGGCGGTGGG GTAAGTGTGG ACCTTTGTGT ACCAGAGAGA ACATCATGGT GGCTTTCAAA 120 GGGGTCTGGA CTCAAGCTTT CTGGAAAGCA GTCACAGCGG AATTTCTGGC CATGCTTATT 180 TTTGTTCTCC TCAGCCTGGG ATCCACCATC AACTGCGGTG GAACAGAAAA GCCTTTACCG 240 GTCGACATGG TTCTCATCTC CCTTTGCTTT GGACTCAGCA TTGCAACCAT GGTGCAGTGC 300 TTTGGCCATA TCAGCGGTGG CCACATCAAC CCTGCAGTGA CTGTGGCCAT GGTGTGCACC 360 AGGAAGATCA GCATCGCCAA GTCTGTCTTC TACATCGCAG CCCAGTGCCT GGGGGCCATC 420 ATTGGAGCAG GAATCCTCTA TCTGGTCACA CCTCCCAGTG TGGTGGGAGG CCTGGGAGTC 480 ACCATGGTTC ATGGAAATCT TACCGCTGGT CATGGTCTCC TGGTTGAGTT GATAATCACA 540 TTTCAATTGG TGTTTACTAT CTTTGCCAGC TCTGATTCCA AACGGACTGA TGTCACTGGC 600 TCAATAGCTT TAGCAATTGG ATTTTCTGTT GCAATTGGAC ATTTATTTGC AATCAATTAT 660 ACTGGTGCCA GCATGAATCC CGCCCGATCC TTTGGACCTG CAGTTATCAT GGGAAATTGG 720 GAAAACCATT GGATATATTG GGTTGGGCCC ATCATAGGAG CTGTCCTCGC TGGTGGCCTT 780 TATGAGTATG TCTTCTGTCC AGATGTTGAA TTCAAACGTC GTTTTAAAGA AGCCTTCAGC 840 AAAGCTGCCC AGCAAACAAA AGGAAGCTAC ATGGAGGTGG AGGACAACAG GAGTCAGGTA 900 GAGACGGATG ACCTGATTCT AAAACCTGGA GTGGTGCATG TGATTGACGT TGACCGGGGA 960 GAGGAGAAGA AGGGGAAAGA CCAATCTGGA GAGGTATTGT CTTCAGTATG ACTAGAAGAT 1020 CGCACTGAAA GCAGACAAGA CTCCTTAGAA CTGTCCTCAG ATTTCCTTCC ACCCATTAAG 1080 GAAACAGATT TGTTATAAAT TAGAAATGTG CAGGTTTGTT GTTTCATGTC ATATTACTCA 1140 GTCTAAACAA TAAATATTTC ATAATTTACA AAGGAGGAAC GGAAGAAACC TATTGTGAAT 1200 TCCAAATCTA AAAAAAGAAA TATTTTTAAG ATGTTCTTAA GCAAATATAT ACCTATTTTA 1260 TCTAGTTACC TTTCATTAAC AACCAATTTT AACCGTGTGT CAAGATTTGG TTAAGTCTTG 1320 CCTGACAGAA CTCAAAGACA CGTCTATCAG CTTATTCCTT CTCTACTGGA ATATTGGTAT 1380 AGTCAATTCT TATTTGAATA TTTATTCTAT TAAACTGAGT TTAACAATGG C '
Seq ID NO: 254 Protein sequence Protein Accession tf: NP 001641.1
1 11 21 31 41 51
I I I I I I
MSDRPTARRW GKCGPLCTRE NIMVAFKGVW TQAFWKAVTA EFLAMLIFVL LSLGSTINWG 60
GTEKPLPVDM VLISLCFGLS IATMVQCFGH ISGGHINPAV TVAMVCTRKI SIAKSVFYIA 120
AQCLGAIIGA GILYLVTPPS WGGLGVTMV HGNLTAGHGL LVELIITFQL VFTIFASCDS 180
KRTDVTGSIA LAIGFSVAIG HLFAINYTGA SMNPARSFGP AVIMGNWENH WIYWVGPIIG 240
AVLAGGLYEY VFCPDVEFKR RFKEAFSKAA QQTKGSYMEV EDNRSQVETD DLILKPGWH 300 VIDVDRGEEK KGKDQSGEVL SSV
Seq ID NO: 255 DNA sequence Nucleic Acid Accession #: U26742.1 Coding sequence: 325..1449
11 21 31 41 51
I I I I I
CAGGAAACCC TGGTACTGGC AGCAGCCAGC CTCTGCTGTG CCCACATGAC CCACAACTCT 60 GGCAGCGGAC CCGGCACTTC CAACATTATT AAATAATAAG AAAGCGGCTC CTACTCCAGG 120 CTCAAACCTC CCTGCAGACC AATGGACACC TTCTAAGAGT TTGGCGAGTC AGTGACTGAA 180 GCGCCCGTCC ATTCCAAGAT AAATAGGATT TACCAATCCT TGGATGAAGT GCTTGGGAAG 240 TCTTTAAGTG CCATAATCAA CTGCCATTTC AAAGAATATA GATGGTTTTG AAAAGTTCAT 300 GCTGTCCCTT CATTGAATTT TAGAATGATT GAAGATAGTG GGAAAAGAGG AAATACCATG 360 GCAGAAAGAA GACAGCTGTT TGCAGAGATG AGGGCTCAAG ATCTGGATCG CATCCGACTC 420 TCCACCTACA GAACAGCATG CAAGCTTAGG TTTGTTCAGA AGAAATGCAA TTTGCACCTG 480 GTGGACATAT GGAATGTCAT AGAAGCATTG CGGGAAAATG CTCTGAACAA CCTGGACCCA 540 AACAGTGAAC TCAACGTGTC CCGCTTAGAG GCTGTGCTCT CCACTATTTT TTACCAGCTC 600 AACAAACGGA TGCCAACCAC TCACCAAATC CATGTGGAGC AGTCCATCAG CCTCCTCCTT 660 AACTTCCTGC TTGCAGCGTT TGATCCGGAA GGCCATGGTA AAATTTCAGT ATTTGCTGTC 720 AAAATGGCTT TAGCCACATT GTGTGGAGGG AAGATCATGG ACAAATTAAG ATATATTTTC 780 TCAATGATTT CTGACTCCAG TGGGGTGATG GTTTATGGAC GATATGACCA ATTCCTTCGG 840 GAAGTTCTCA AACTACCCAC GGCAGTTTTT GAAGGTCCTT CATTTGGTTA CACAGAACAG 900 TCAGCCAGAT CCTGTTTCTC CCAACAGAAA AAAGTCACGT TAAATGGTTT CTTGGACACG 960 CTTATGTCAG ATCCTCCCCC GCAGTGTCTG GTCTGGTTGC CTCTTCTGCA TCGACTAGCA 1020 AATGTGGAAA ATGTCTTCCA TCCGGTTGAG TGTTCCTACT GCCACAGTGA GAGTATGATG 1080 GGATTTCGCT ACCGATGCCA ACAGTGTCAC AATTACCAGC TCTGTCAGGA CTGCTTCTGG 1140 AGGGGACATG CCGGTGGTTC TCATAGCAAC CAGCACCAAA TGAAAGAGTA CACGTCATGG 1200 AAATCACCTG CTAAGAAGCT GACTAATGCA TTAAGCAAGT CCCTGAGCTG TGCTTCCAGC 1260 CGTGAACCTT TGCACCCCAT GTTCCCAGAT CAGCCTGAGA AGCCACTCAA CTTGGCTCAC 1320 ATCGTTGATA CTTGGCCTCC CAGACCTGTA ACCAGCATGA ACGACACCCT GTTCTCCCAC 1380 TCTGTTCCCT CCTCAGGAAG TCCTTTTATT ACCAGGAGCT CGGACGGTGC TTTTGGTGGA 1440 TGCGTCTAGA TGGATAACAT GACTTCTTCT ACCCTAAAAT ATTCCTATAA TACTTTGAGC 1500 TGTTCTGGTT CCTCCAGGGT GCATGGTACC CATTAACCCA AAATATGATT ATTTCCCTTT 1560 TTTCCCATTT TCAGTCATTT TGGAATGTTC TCTGTGAACC ACAGTTGGGT TGTTTAAAGC 1620 TCACATTTCT TTCTGTCACC ACAGAGATTG GCCTACGGTT TCTGTTTTGA GGGTGCTGTT 1680 CAATAAAGCT GTGTACACTA AATGTCC
Seq ID NO: 256 Protein εequence Protein Acceεsion ft: AAC50424.1
11 21 31 41 51
I I I I I
MIEDSGKRGN TMAERRQLFA EMRAQDLDRI RLSTYRTACK LRFVQKKCNL HLVDIWNVIE 60 ALRENALNNL DPNTELNVSR LEAVLSTIFY QLNKRMPTTH QIHVEQSISL LLNFLLAAFD 120 PEGHGKISVF AVKMALATLC GGKIMDKLRY IFSMISDSSG VMVYGRYDQF LREVLKLPTA 180 VFEGPSFGYT EQSARSCFSQ QKKVTLNGFL DTLMSDPPPQ CLVWLPLLHR LANVENVFHP 240 VECSYCHSES MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT 300 NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVDTWPPR PVTSMNDTLF SHSVPSSGSP 360 FITRSSDGAF GGCV
Seq ID NO: 257 DNA sequence
Nucleic Acid Accesεion ft: NM_004172.1
Coding sequence: 179..1807
11 21 31 41 51
I I I I
GCGGATTGTT GCTCCGTTGT ACCTGCTGGG GAATTCACCT CGTTACTGCT TGATATCTTC 60 CACCCCTTAC AAAATCAGAA AAGTTGTGTT TTCTAATACC AAAGAGGAGG TTTGGCTTTC ' 120 TGTGGGTGAT TCCCAGACAC TGAAGTGCAA AGAAGAGACC CTCCTAGAAA AGTAAAATAT 180 GACTAAAAGC AATGGAGAAG AGCCCAAGAT GGGGGGCAGG ATGGAGAGAT TCCAGCAGGG 240 AGTCCGTAAA CGCACACTTT TGGCCAAGAA GAAAGTGCAG AACATTACAA AGGAGGATGT 300 TAAAAGTTAC CTGTTTCGGA ATGCTTTTGT GCTGCTCACA GTCACCGCTG TCATTGTGGG 360 TACAATCCTT GGATTTACCC TCCGACCATA CAGAATGAGC TACCGGGAAG TCAAGTACTT 420 CTCCTTTCCT GGGGAACTTC TGATGAGGAT GTTACAGATG CTGGTCTTAC CACTTATCAT 480 CTCCAGTCTT GTCACAGGAA TGGCGGCGCT AGATAGTAAG GCATCAGGGA AGATGGGAAT 540 GCGAGCTGTA GTCTATTATA TGACTACCAC CATCATTGCT GTGGTGATTG GCATAATCAT 600 TGTCATCATC ATCCATCCTG GGAAGGGCAC AAAGGAAAAC ATGCACAGAG AAGGCAAAAT 660 TGTACGAGTG ACAGCTGCAG ATGCCTTCCT GGACTTGATC AGGAACATGT TCCCTCCAAA 720 TCTGGTAGAA GCCTGCTTTA AACAGTTTAA AACCAACTAT GAGAAGAGAA GCTTTAAAGT 780 GCCCATCCAG GCCAACGAAA CGCTTGTGGG TGCTGTGATA AACAATGTGT CTGAGGCCAT 840 GGAGACTCTT ACCCGAATCA CAGAGGAGCT GGTCCCAGTT CCAGGATCTG TGAATGGAGT 900 CAATGCCCTG GGTCTAGTTG TCTTCTCCAT GTGCTTCGGT TTTGTGATTG GAAACATGAA 960 GGAACAGGGG CAGGCCCTGA GAGAGTTCTT TGATTCTCTT AACGAAGCCA TCATGAGACT 1020 GGTAGCAGTA ATAATGTGGT ATGCCCCCGT GGGTATTCTC TTCCTGATTG CTGGGAAGAT 1080 TGTGGAGATG GAAGACATGG GTGTGATTGG GGGGCAGCTT GCCATGTACA CCGTGACTGT 1140 CATTGTTGGC TTACTCATTC ACGCAGTCAT CGTCTTGCCA CTCCTCTACT TCTTGGTAAC 1200 ACGGAAAAAC CCTTGGGTTT TTATTGGAGG GTTGCTGCAA GCACTCATCA CCGCTCTGGG 1260 GACCTCTTCA AGTTCTGCCA CCCTACCCAT CACCTTCAAG TGCCTGGAAG AGAACAATGβ 1320 CGTGGACAAG CGCGTCACCA GATTCGTGCT CCCCGTAGGA GCCACCATTA ACATGGATGG 1380 GACTGCCCTC TATGAGGCTT TGGCTGCCAT TTTCATTGCT CAAGTTAACA ACTTTGAACT 1440 GAACTTCGGA CAAATTATTA CAATCAGCAT CACAGCCACA GCTGCCAGTA TTGGGGCAGC 1500 TGGAATTCCT CAGGCGGGCC TGGTCACTAT GGTCATTGTG CTGACATCTG TCGGCCTGCC 1560 CACTGACGAC ATCACGCTCA TCATCGCGGT GGACTGGTTC CTGGATCGCC TCCGGACCAC 1620 CACCAACGTA CTGGGAGACT CCCTGGGAGC TGGGATTGTG GAGCACTTGT CACGACATGA 1680 ACTGAAGAAC AGAGATGTTG AAATGGGTAA CTCAGTGATT GAAGAGAATG AAATGAAGAA 1740 ACCATATCAA CTGATTGCAC AGGACAATGA AACTGAGAAA CCCATCGACA GTGAAACCAA 1800 GATGTAGACT AACATAAAGA AACACTTTCT TGAGCACCAG GTGTTAAAAA CCATTATAAA 1860 ATCTTTCCAT CTCATTACAG CTCATTCGCT CCAGCAAGCC CGTCATCTTC CCTTTCCTCC 1920 CTTCTGATAA GACTGGAAAA TAGTCCTCCA AAACACAAGG GAGGATTTTG GGTGGCCAAA 1980 GTGTACAATT TTCATCCCAC AATTGAAATT TTTAAATCAT TTCATGTTAG TCTTACCGAA 2040 TAAGGTACCA AGATCACAAA TAGTGTTGAT CAGATCTTAC AAGTTTATGT GGCACACAAT 2100 TCCTATAAAT GTGATTTTTT TATATAAGTT AAAGAGACAA ATAGTAGGCT AAAAACATTT 2160 TAAAATCAAC TTTTGAAATT TAAAAATCTT TCAGAATACA ATTCAGTTTT AGTTTCAAAA 2220 TGTTAACAAC TTGAATTACA ACCGGTTATC AGTTGGACAG TAAGATTTTA TCCCTTTCTC 2280 TTCTGACTGG TATACCTATT TCATTAGTAG CTAGGTGCAC ATATACATCT AGCACAGCTG 2340 TGAGGACAGA CAGAAGGCAA AGTTTCCATG TGGCCTTGAG CAAGTCCCAT CTCACCTCTA 2400 GGCCTCAGTG TCCTCATCTA TAAAATGAGG GACTTCCCTA GAAGTCTTCA TGGTCTCTTC 2460 CAGCCCAGAC ATCCTGTGAT GTCATGAAAG CACCTGCCCT CTGTTTCCCC TCAGAACACC 2520 CTGTACCATC CATGGAGCAC GAGGCCTTCA GAAAAGACAC TTCAATGGGA GTGAACATTT 2580 CTAACTAAGG ACAGGATGGC TGTGTGTGGT GGTCACCAGG TCCTGTGAGC AAAGTGCAGG 2640 TTATGCAAGT CGCCAGGCAG GAGGCCATTC CAGGAGTGGG ATTATTCATC AAACTCTTTG 2700 CCCAGTTCAT CCCAATGGGG GAAGTATTCC CTTCTTTCCT ACTCTGGGAA GAATGTCTCC 2760 TGCCACTCCT CAACTGATGA TAGACTTCGA AAACAGATGA GAAGACTAGC AGCTAGCAAG 2820 GGTGCTTGTA GTCACACTGT GGAACACTAA AGAGCTAGGA AAGAGTTGAG CACAGGCAAC 2880 ATTACAAACA AAGGATTTGA AAACACCAAG AGTACAGGTC TTCTTTAAGG AAGAATAAAA 2940 AAGAAGAGGT TCATTTTTCT GGCTTTTTTT TTCACCTGAA ACACTTTTTC TCGAGTCCAA 3000 AATCATTCCC CCCGTGAAGT CTGCTTACCA AAACATAAGA CGACTTATAT ATTTGAAAGA 3060 AGTCAAATGA ATGAGCTCTC TAATAGAAGT CCATGAGTTG AGTGGGTATT TCTTATTTGA 3120 AAGTGTTTTT CTTTAATCAA AAGTCCTTAG AATGAGGGAA ACAAAATATT TATTTGTTTT 3180 GGAATCCCAC TTATCAAATC ATTCAAAACT TTCAGCTGGA GTGGGGTTTG CTTTTGTTTT 3240 GTTTGTGTCC ATAAGAGAAA TGGTAGAAGA TGAATCAGTA TGAAGACACT GTCAATGAGG 3300 TTATGAGAAA AAAACAGCAG GGGCATTAGT TTCAGGCAAG GCAGCTCCCA GGTTTAGAGA 3360 TTAATTTTTA CCCCCTAAGG AATATCCAGT CAAAGACGCT GAGTGGGAGC TGTCAGGCAG 3420 TAGCAGCTGT GTTTGAGTTT CTGGCTGAAA ATGGTGAAGA ATGGACTTAA TTATGCTAAC 3480 AAACTGAAAA ATCTAGACAT AGATCCTCTG ATATACAATT AGAGATATTT TTATATAGAC 3540 CCCAAGCATT CTGTGCATAA AAGTTAACAT TAGGCTGTGG TGCAGTAACC ATTTAATGTC 3600 GAGGCTCTAT TTCGGAAATA CACTACAAAT GTTAAAGTAC GTGGCTGTCC TCTTAAGACA 3660 CTAGTAGAGC AAAGACTTAA TCATATCAAC TTAATTCTGT TACACAATAT GTGTTTTTTA 3720 ATATACTAAC CATTTCTTAT GGAAAGGTCC TGTGGGGAGC CCATCCTCTC GCCAAGCCAT 3780 CACAGGCTCT GCATACACAT GCACTCAGTG TGGACTGGGA AGCATTACTT TGTAGATGTA 3840 TTTTCAATAA AGAAAAAAAT AGTTTTACAT T
Seq ID NO: 258 Protein sequence Protein Accession ft: NP 004163.1
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MTKSNGEEPK MGGRMERFQQ GVRKRTLLAK KKVQNITKED VKSYLFRNAF VLLTVTAVIV 60 GTILGFTLRP YRMSYREVKY FSFPGELLMR MLQMLVLPLI ISSLVTGMAA LDSKASGKMG 120 MRAWYYMTT TIIAWIGII IVIIIHPGKG TKENMHREGK IVRVTAADAF LDLIRNMFPP 180 NLVEACFKQF KTNYEKRSFK VPIQANETLV GAVINNVSEA METLTRITEE LVPVPGSVNG 240 VNALGLWFS MCFGFVIGNM KEQGQALREF FDSLNEAIMR LVAVIMWYAP VGILFLIAGK 300 IVEMEDMGVI GGQLAMYTVT VIVGLLIHAV IVLPLLYFLV TRKNPWVFIG GLLQALITAL 360 GTSSSSATLP ITFKCLEENN GVDKRVTRFV LPVGATINMD GTALYEALAA IFIAQVNNFE 420 LNFGQIITIS ITATAASIGA AGIPQAGLVT MVIVLTSVGL PTDDITLIIA VDWFLDRLRT 480 TTNVLGDSLG AGIVEHLSRH ELKNRDVEMG NSVIEENEMK KPYQLIAQDN ETEKPIDSET 540 KM
Seq ID NO: 259 DNA εequence
Nucleic Acid Accession ft: NM_021948.1
Coding εequence: 48..2783
1 11 21 31 41 51
1 | 1 | 1 | 1 | 1 1 TGTGGCACTG CCTGCGTACC CAACCCCAGC CCTGGGTAGC CTGCAGCATG GCCCAGCTGT 60
TCCTGGCCCT GCTGGCAGCC CTGGTCCTGG CCCAGGCTCC TGCAGCTTTA GCAGATGTTC 120
TGGAAGGAGA CAGCTCAGAG GACCGCGCTT TTCGCGTGCG CATCGCGGGC GACGCGCCAC 180
TGCAGGGCGT GCTCGGCGGC GCCCTCACCA TCCCTTGCCA CGTCCACTAC CTGCGGCCAC 240
CGCCGAGCCG CCGGGCTGTG CTGGGCTCTC CGCGGGTCAA GTGGACTTTC CTGTCCCGGG 300
GCCGGGAGGC AGAGGTGCTG GTGGCGCGGG GAGTGCGCGT CAAGGTGAAC GAGGCCTACC 360
GGTTCCGCGT GGCACTGCCT GCGTACCCAG CGTCGCTCAC CGACGTCTCC CTGGCGCTGA 420
GCGAGCTGCG CCCCAACGAC TCAGGTATCT ATCGCTGTGA GGTCCAGCAC GGCATCGATG 480
ACAGCAGCGA CGCTGTGGAG GTCAAGGTCA AAGGGGTCGT CTTTCTCTAC CGAGAGGGCT 540
CTGCCCGCTA TGCTTTCTCC TTTTCTGGGG CCCAGGAGGC CTGTGCCCGC ATTGGAGCCC 600
ACATCGCCAC CCCGGAGCAG CTCTATGCCG CCTACCTTGG GGGCTATGAG CAATGTGATG 660
CTGGCTGGCT GTCGGATCAG ACCGTGAGGT ATCCCATCCA GACCCCACGA GAGGCCTGTT 720
ACGGAGACAT GGATGGCTTC CCCGGGGTCC GGAACTATGG TGTGGTGGAC CCGGATGACC 780
TCTATGATGT GTACTGTTAT GCTGAAGACC TAAATGGAGA ATTGTTCCTG GGTGACCCTC 840
CAGAGAAGCT GACATTGGAG GAAGCACGGG CGTACTGCCA GGAGCGGGGT GCAGAGATTG 900
CCACCACGGG CCAACTGTAT GCAGCCTGGG ATGGTGGCCT GGACCACTGC AGCCCAGGGT 960
GGCTAGCTGA TGGCAGTGTG CGCTACCCCA TCGTCACACC CAGCCAGCGC TGTGGTGGGG 1020
GCTTGCCTGG TGTCAAGACT CTCTTCCTCT TCCCCAACCA GACTGGCTTC CCCAATAAGC 1080
ACAGCCGCTT CAACGTCTAC TGCTTCCGAG ACTCGGCCCA GCCTTCTGCC ATCCCTGAGG 1140
CCTCCAACCC AGCCTCCAAC CCAGCCTCTG ATGGACTAGA GGCTATCGTC ACAGTGACAG 1200
AGACCCTGGA GGAACTGCAG CTGCCTCAGG AAGCCACAGA GAGTGAATCC CGTGGGCCCA 1260
TCTACTCCAT CCCCATCATG GAGGACGGAG GAGGTGGAAG CTCCACTCCA GAAGACCCAG 1320
CAGAGGCCCC TAGGACGCTC CTAGAATTTG AAACACAATC CATGGTACCG CCCACGGGGT 1380 TCTCAGAAGA GGAAGGTAAG GCATTGGAGG AAGAAGAGAA ATATGAAGAT GAAGAAGAGA 1440 AAGAGGAGGA AGAAGAAGAG GAGGAGGTGG AGGATGAGGC TCTGTGGGCA TGGCCCAGCG 1500 AGCTCAGCAG CCCGGGCCCT GAGGCCTCTC TCCCCACTGA GCCAGCAGCC CAGGAGGAGT 1560 CACTCTCCCA GGCGCCAGCA AGGGCAGTCC TGCAGCCTGG TGCATCACCA CTTCCTGATG 1620 GAGAGTCAGA AGCTTCCAGG CCTCCAAGGG TCCATGGACC ACCTACTGAG ACTCTGCCCA 1680 CTCCCAGGGA GAGGAACCTA GCATCCCCAT CACCTTCCAC TCTGGTTGAG GCAAGAGAGG 1740 TGGGGGAGGC AACTGGTGGT CCTGAGCTAT CTGGGGTCCC TCGAGGAGAG AGCGAGGAGA 1800 CAGGAAGCTC CGAGGGTGCC CCTTCCCTGC TTCCAGCCAC ACGGGCCCCT GAGGGTACCA 1860 GGGAGCTGGA GGCCCCCTCT GAAGATAATT CTGGAAGAAC TGCCCCAGCA GGGACCTCAG 1920 TGCAGGCCCA GCCAGTGCTG CCCACTGACA GCGCCAGCCG AGGTGGACTG GCCGTGGTCC 1980 CCGCATCAGG TGACTGTGTC CCCAGCCCCT GCCACAATGG TGGGACATGC TTGGAGGAGG 2040 AGGAAGGGGT CCGCTGCCTA TGTCTGCCTG GCTATGGGGG GGACCTGTGC GATGTTGGCC 2100 TCCGCTTCTG CAACCCCGGC TGGGACGCCT TCCAGGGCGC CTGCTACAAG CACTTTTCCA 2160 CACGAAGGAG CTGGGAGGAG GCAGAGACCC AGTGCCGGAT GTACGGCGCG CATCTGGCCA 2220 GCATCAGCAC ACCCGAGGAA CAGGACTTCA TCAACAACCG GTACCGGGAG TACCAGTGGA 2280 TCGGACTCAA CGACAGGACC ATCGAAGGCG ACTTCTTGTG GTCGGATGGC GTCCCCCTGC 2340 TCTATGAGAA CTGGAACCCT GGGCAGCCTG ACAGCTACTT CCTGTCTGGA GAGAACTGCG 2400 TGGTCATGGT GTGGCATGAT CAGGGACAAT GGAGTGACGT GCCCTGCAAC TACCACCTGT 2460 CCTACACCTG CAAGATGGGG CTGGTGTCCT GTGGGCCGCC ACCGGAGCTG CCCCTGGCTC 2520 AAGTGTTCGG CCGCCCACGG CTGCGCTATG AGGTGGACAC TGTGCTTCGC TACCGGTGCC 2580 GGGAAGGACT GGCCCAGCGC AATCTGCCGC TGATCCGATG CCAAGAGAAC GGTCGTTGGG 2640 AGGCCCCCCA GATCTCCTGT GTGCCCAGAA GACCTGCCCG AGCTCTGCAC CCAGAGGAGG 2700 ACCCAGAAGG ACGTCAGGGG AGGCTACTGG GACGCTGGAA GGCGCTGTTG ATCCCCCCTT 2760 CCAGCCCCAT GCCAGGTCCC TAGGGGGCAA GGCCTTGAAC ACTGCCGGCC ACAGCACTGC 2820 CCTGTCACCC AAATTTTCCC TCACACCCTG CGCTCACCAC AGGAAGTGAC AACATGAC
Seq ID NO: 260 Protein sequence Protein Accesεion #: NP 068767.1
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MAQLFLPLLA ALVLAQAPAA LADVLEGDSS EDRAFRVRIA GDAPLQGVLG GALTIPCHVH 60 YLRPPPSRRA VLGSPRVKWT FLSRGREAEV LVARGVRVKV NEAYRFRVAL PAYPASLTDV 120 SLALSELRPN DSGIYRCEVQ HGIDDSSDAV EVKVKGWFL YREGSARYAF SFSGAQEACA 180 RIGAHIATPE QLYAAYLGGY EQCDAGWLSD QTVRYPIQTP REACYGDMDG FPGVRNYGW 240 DPDDLYDVYC YAEDLNGELF LGDPPEKLTL EEARAYCQER GAEIATTGQL YAAWDGGLDH 300 CSPGWLADGS VRYPIVTPSQ RCGGGLPGVK TLFLFPNQTG FPNKHSRFNV YCFRDSAQPS 360 AIPEASNPAS NPASDGLEAI VTVTETLEEL QLPQEATESE SRGAIYSIPI MEDGGGGSST 420 PEDPAEAPRT LLEFETQSMV PPTGFSEEEG KALEEEEKYE DEEEKEEEEE EEEVEDEALW 480 AWPSELSSPG PEASLPTEPA AQEESLSQAP ARAVLQPGAS PLPDGESEAS RPPRVHGPPT 540 ETLPTPRERN LASPSPSTLV EAREVGEATG GPELSGVPRG ESEETGSSEG APSLLPATRA 600 PEGTRELEAP SEDNSGRTAP AGTSVQAQPV LPTDSASRGG VAWPASGDC VPSPCHNGGT 660 CLEEEEGVRC LCLPGYGGDL CDVGLRFCNP GWDAFQGACY KHFSTRRSWE EAETQCRMYG 720 AHLASISTPE EQDFINNRYR EYQWIGLNDR TIEGDFLWSD GVPLLYENWN PGQPDSYFLS 780 GENCWMVWH DQGQWSDVPC NYHLSYTCKM GLVSCGPPPE LPLAQVFGRP RLRYEVDTVL 840 RYRCREGLAQ RNLPLIRCQE NGRWEAPQIS CVPRRPARAL HPEEDPEGRQ GRLLGRWKAL 900 LIPPSSPMPG P
Seq ID NO: 261 DNA sequence
Nucleic Acid Accession #: NM_004386.1
Coding sequence: 2.-3967
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GATGGGGGCC CCGTTTGTCT GGGCCTTGGG CCTTTTGATG CTGCAGATGC TGCTCTTTGT 60 GGCTGGGGAA CAGGGCACAC AGGATATCAC CGATGCCAGC GAAAGGGGGC TCCACATGCA 120 GAAGCTGGGG TCTGGGTCAG TGCAGGCTGC GCTGGCGGAG CTGGTGGCCC TGCCCTGTCT 180 CTTTACCCTG CAGCCACGGC CAAGCGCAGC CCGAGATGCC CCTCGGATAA AGTGGACCAA 240 GGTGCGGACT GCGTCGGGCC AGCGACAGGA CTTGCCCATC CTGGTGGCCA AGGACAATGT 300 CGTGAGGGTG GCCAAAAGCT GGCAGGGACG AGTGTCACTG CCTTCCTACC CCCGGCGCCG 360 AGCCAACGCC ACGCTACTTC TGGGGCCACT GAGGGCCAGT GACTCTGGGC TGTACCGCTG 420 CCAGGTGGTG AGGGGCATCG AGGATGAGCA GGACCTGGTG CCCTTGGAGG TGACAGGTGT 480 TGTGTTCCAC TACCGATCAG CCCGGGACCG CTATGCACTG ACCTTCGCTG AGGCCCAGGA 540 GGCCTGCCGT CTCAGCTCAG CCATCATTGC AGCCCCTCGG CATCTACAGG CTGCCTTTGA 600 GGATGGCTTT GACAACTGTG ATGCTGGCTG GCTCTCTGAC CGCACTGTTC GGTATCCTAT 660 CACCCAGTCC CGTCCTGGTT GCTATGGCGA CCGTAGCAGC CTTCCAGGGG TTCGGAGCTA 720 TGGGAGGCGC AACCCACAGG AACTCTACGA TGTGTATTGC TTTGCCCGGG AGCTGGGGGG 780 CGAGGTCTTC TACGTGGGCC CGGCCCGCCG CCTGACACTG GCCGGCGCGC GTGCACAGTG 840 CCGCCGCCAG GGTGCCGCGC TGGCCTCGGT GGGACAGCTG CACCTGGCCT GGCATGAGGG 900 CCTGGACCAG TGCGACCCGG GCTGGCTGGC CGACGGCAGC GTGCGCTACC CGATCCAGAC 960 GCCGCGCCGG CGCTGCGGGG GCCCAGCCCC GGGCGTGCGC ACCGTCTACC GCTTCGCTAA 1020 CCGGACCGGC TTCCCCTCAC CCGCCGAGCG CTTCGACGCC TACTGCTTCC GAGCTCATCA 1080 CCCCACGTCA CAACATGGAG ACCTAGAGAC CCCATCCTCT GGGGATGAGG GGGAGATTCT 1140 GTCAGCAGAG GGGCCCCCAG TTAGAGAACT GGAGCCCACC CTGGAGGAGG AAGAGGTGGT 1200 CACCCCTGAC TTCCAGGAGC CTCTGGTGTC CAGTGGGGAA GAAGAAACCC TGATTTTGGA 1260 GGAGAAGCAG GAGTCTCAAC AGACCCTCAG CCCTACCCCT GGGGACCCCA TGCTGGCCTC 1320 ATGGCCCACT GGGGAAGTGT GGCTAAGCAC GGTGGCCCCC AGCCCTAGCG ACATGGGGGC 1380 AGGCACTGCA GCAAGTTCAC ACACGGAGGT GGCCCCAACT GACCCTATGC CTAGGAGAAG 1440 GGGGCGCTTC AAAGGGTTGA ATGGGCGCTA CTTCCAGCAG CAGGAACCGG AGCCGGGGCT 1500 GCAAGGGGGG ATGGAGGCCA GCGCCCAGCC CCCCACCTCA GAGGCTGCAG TGAACCAAAT 1560 GGAGCCTCCG TTGGCCATGG CAGTCACAGA GATGTTGGGC AGTGGCCAGA GCCGGAGCCC 1620 CTGGGCTGAT CTGACCAATG AGGTGGATAT GCCTGGAGCT GGTTCTGCTG GTGGCAAGAG 1680 CTCCCCAGAG CCCTGGCTGT GGCCCCCTAC CATGGTCCCA CCCAGCATCT CAGGCCACAG 1740 CAGGGCCCCT GTCCTGGAGC TAGAGAAAGC CGAGGGCCCC AGTGCCAGGC CAGCCACCCC 1800 AGACCTGTTT TGGTCCCCCT TGGAGGCCAC TGTCTCAGCT CCCAGCCCTG CCCCCTGGGA 1860
GGCATTCCCT GTGGCCACCT CCCCAGATCT CCCTATGATG GCCATGCTGC GTGGTCCCAA 1920
AGAGTGGATG CTACCACACC CCACCCCCAT CTCCACCGAG GCCAATAGAG TTGAGGCACA 1980
TGGTGAGGCC ACCGCCACGG CTCCACCCTC CCCTGCTGCA GAGACCAAGG TGTATTCCCT 2040
GCCTCTCTCT TTGACCCCAA CAGGACAGGG TGGAGAGGCC ATGCCCACAA CACCTGAGTC 2100
CCCCAGGGCA GACTTCAGAG AAACTGGGGA GACCAGCCCT GCTCAGGTCA ACAAAGCTGA 2160
GCACTCCAGC TCCAGCCCAT GGCCTTCTGT AAACAGGAAT GTGGCTGTAG GTTTTGTCCC 2220
CACTGAGACT GCCACTGAGC CAACGGGCCT CAGGGGTATC CCGGGGTCTG AGTCTGGGGT 2280
CTTCGACACA GCAGAAAGCC CCACTTCTGG CTTGCAGGCC ACTGTAGATG AGGTGCAGGA 2340
CCCCTGGCCC TCAGTGTACA GCAAAGGGCT GGATGCAAGT TCCCCATCTG CCCCCCTGGG 2400
GAGCCCTGGA GTCTTCTTGG TACCCAAACT CACCCCAAAT TTGGAGCCTT GGGTTGCTAC 2460
'AGATGAAGGA CCCACTGTGA ATCCCATGGA TTCCACAGTC ACGCCGGCCC CCAGTGATGC 2520
TAGTGGAATT TGGGAACCTG GATCCCAGGT GTTTGAAGAA GCCGAAAGCA CCACCTTGAG 2580
CCCTCAGGTG GCCCTGGATA CAAGCATTGT GACGCCCCTC ACGACCCTGG AGCAGGGGGA 2640
CAAGGTTGGA GTTCCAGCCA TGTCTACACT GGGCTCCTCA AGCTCCCAAC CCCACCCAGA 2700
GCCAGAGGAT CAGGTGGAGA CCCAGGGAAC ATCAGGAGCT TCAGTGCCTC CGCATCAGAG 2760
CAGTCCCCTA GGGAAACCGG CTGTTCCTCC TGGGACACCG ACTGCAGCCA GTGTGGGCGA 2820
GTCTGCCTCA GTTTCCTCAG GGGAGCCTAC GGTACCGTGG GACCCCTCCA GCACCCTGCT 2880
GCCTGTCACC CTGGGCATAG AGGACTTCGA ACTGGAGGTC CTGGCAGGGA GCCCGGGTGT 2940
AGAGAGCTTC TGGGAGGAGG TGGCAAGTGG AGAGGAGCCA GCCCTGCCAG GGACCCCTAT 3000
GAATGCAGGT GCGGAGGAGG TGCACTCAGA TCCCTGTGAG AACAACCCTT GTCTTCATGG 3060
AGGGACATGT AATGCCAATG GCACCATGTA TGGCTGTAGC TGTGATCAGG GCTTCGCCGG 3120
GGAGAACTGT GAGATTGACA TTGATGACTG CCTCTGCAGC CCCTGTGAGA ATGGAGGCAC 3180
CTGTATTGAT GAGGTCAATG GCTTTGTCTG CCTTTGCCTC CCCAGCTATG GGGGCAGCTT 3240
TTGTGAGAAA GACACCGAGG GCTGTGACCG CGGCTGGCAT AAGTTCCAGG GCCACTGTTA 3300
CCGCTATTTT GCCCACCGGA GGGCATGGGA AGATGCCGAG AAGGACTGCC GCCGCCGCTC 3360
CGGCCACCTG ACCAGCGTCC ACTCAGCGGA GGAACACAGC TTCATTAATA GCTTTGGGCA 3420
TGAAAACACG TGGATCGGCC TGAACGACAG GATCGTGGAG AGAGATTTCC AGTGGACGGA 3480
CAACACCGGG CTGCAATTTG AGAACTGGCG AGAGAACCAG CCGGACAATT TCTTCGCGGG 3540
TGGCGAGGAC TGTGTGGTGA TGGTGGCGCA TGAAAGCGGG CGCTGGAACG ATGTCCCCTG 3600
CAACTACAAC CTACCCTATG TCTGCAAGAA GGGCACAGTG CTCTGTGGTC CCCCTCCGGC 3660
AGTGGAGAAT GCCTCACTCA TCGGTGCCCG CAAGGCCAAG AACAATGTCC ATGCCACTGT 3720
AAGGTACCAG TGCAATGAAG GATTTGCCCA GCACCATGTG GTCACCATTC GATGCCGGAG 3780
CAATGGCAAG TGGGACAGGC CCCAAATTGT CTGCACCAAA CCCAGACGTT CACATCGGAT 3840
GCGGGGACAC CACCACCACC ACCAACACCA CCACCAGCAT CACCACCACA AATCCCGCAA 3900
GGAGCGCAGA AAACACAAGA AACACCCAAC GGAGGACTGG GAGAAGGACG AAGGGAATTT 3960 |
TTGCTGAAGA ACCAGAAAAA AGAAAGCACA ACACCTTTCC CATGCCTCCT CTGGAGCCTT 4020 '
CGCCTGGGGA GACAGAACCC AGAGAGAAAG AAGAGAGTCC AGAAGTCCCT GAACCCCAAA 4080
CTGTTCTCGC AAAAAAAATA TTCCTTTGAA CAAAGGTCTT CTTTTCCTTT TTTTACATAC 4140
ACAAGATCTT CTTGGCAGGT GGAGCCAGGT GTCTGAAAAG TTCATTCTCG TCTGGCTGAA 4200
CTCTGGGAGT GTGTCCCAGC TGAGGGAAGC ACAAGTAGCA AAGCTCATTG GTCTGGTCTC 4260
TTGTTTGCCA GGCTGATTGA AGCAGGCCTT GATGAGGGTG CATGAGTGTA TGTTTGCATT 4320
CACATGAAGG AATTGCTTTT CACACCAGAA ATTCAGACTT AGTCAATGTT GGCTGAATTC 4380
CTAAATCCAG GAAGAAGCCT GGACGTAGGG TCATTAGCTT TGGGAATAGA AGGCTACACA 4440
GAAGCACACT GTTTTTGAAC TTGACAACAG CTCTCCCTTT ACCCTGGACT TCAGCCCAAG 4500
TTCCGTCTTT GGTCTTGGTG GATAAACACA CACTGTGGAG ATCCCACGTA CTGCATTTTA 4560
GGGATGTTTT TAGGACAACC TCCCTCCATG CCTTCAGAGT TAGGAGTGAG AATGATCAAA 4620
GCAATATGTA GGTGATGGAG GGAGAGTGTA TTGCTAACCC TTCCAGGTCT AGTCCAGCGC 4680
TGAGATTTGG TGGTTCTGCA TGTGTGATGA ATCTCTTTCA CACAAATAGA CGAGAGGATA 4740
TTTAGGGCTA GATGAGCCCA GATTTCTTCC CCCTCCATCT CTCAGGGAGA CAAAGAACCT 4800
CCTTCCTGGA CCAAGGAGGT GCTGCCAAGT TTTCTAGCCC AGTGCACATA CCCAGTCCTT 4860
AAGCAGACAT TGGTAGTGCC CCTGCCCTGG GTCCCACTCC TGCCCCACCC CACCCTTGTC 4920
CCTGGCCATT GCCTGGTGGT CTAGAAACAC TTAAAACTTG AAGTAGTGAC ACCTACCTGC 4980
GGTCATATTG TAGAGAGATG CTCAGTGTTA AAACTGAAAC ACACAAACAC ACACACACAC 5040
ACATTTTTCT CTTGTAGATT TTAATTTTTT AAGTGGGAAA GAACTCACCT TGCCTTCCTC 5100
CCCCAAATGT GCAACCTGTA AAAGGTCTCT CCACACCAGG GGCCAGGATC CAGTTCCCTC 5160
ATCTCTGGCA GGAAAGATCC ACAGCTTTTC CTCCATGTCT GTTACTCACT TTCAGCAGTC 5220
CGGGTAAAAT CTGTGGATCA GGGTTAAAAA AGCACCGTGG AGAATGGCCC TCTTCAGGAA 5280
AGAAAAATAA GCAAATGAAT GGTCCACCTA GGGGTTCAGT AAAGAAAGAA ATGTGTTAAC 5340
TGAGCCTGAA TCCCTTCTGG GAAGTAATAA TGACCATTGA CAACTAAGAA GTAGACACCA 5400
TGCTAAAGAC TTACATACAA TCTCCTTGAA TCTTCTCAAT AGCCCATTGA CTTAGAAACT 5460
GTTACTTTCC CATTTTACAC ACAGTGAAAC TGAGGCTCAG ATATAAAGGA AAGGTACTGG 5520
CTTGAAGTCA CAACCACGAC AGGAGTAAGG ATTTGGAATA AGGATTTGGT CCTGTTTTCT 5580
GGACCAAATC CTTACTCTGG CTCTGCTTAC ACTTTCTCTC CATCACCAAA TCCTTACTCC 5640
AAATCCAGAA GTCAGAGCCA ACTCCCATCT TGGTTCTGAC CCAAATCCTG CTCTGGACTC 5700
TGGAGAGGAG ATTGAAATAT AATTGCACCC TCATACACAT TTAGGAAATG GTTAAGAAGT 5760
GTAAACTGAA CCCTTATCCT TGTCTTCAAT CTTCCTCCCT GTAGACATCT ATCTTATTAT 5820
GGTTATTATT CAGAAAACCC AGGGATACAG GTTTGTCTTC TTACTTTGAT AACTCTTCTT 5880
AGTTTAAAAT AATAATAATA ACACATCTTT GGTCATCTAT GTCACACAAA AATTTTCCTT 5940
TGTTTGCGGG GGGCTGGGGA TGCAGTGTTT TTTGGGGGGT CTTGGTTTAT GCTCCCTGCC 6000
CTTGAGCCCC TCAGCCGTTT GCCCTGCCCC CACCTCGGCT CCATGGTGGG AGGGGGCTCT 6060
GGTCTTTTCT AAAGTGGGCG GTTTGTCTTT TGATCTTTCC CTTTTGGATG TGCGTGTGTG 6120
TCTGCGTGTG CCATGTGCGT GGCACGCATA TGAGTGTGTG TGCGTGTGAA CGGCTTTGGG 6180
TCCTGCTGGT TTTGCTGTGA GCTGCAGTGT TCTGTGGGTC TGTGGTATCT GACACTGTGG 6240
ACATTAATGT ACTTCTTGGA CATTTTAATA AATTTTTTAA CAGTTCAAAA AAAAAAAAAA 6300 AAAAAAAAAA
Seq ID NO: 262 Protein sequence Protein Accession #: NP 004377.1
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MGAPFVWALG LLMLQMLLFV AGEQGTQDIT DASERGLHMQ KLGSGSVQAA LAELVALPCL FTLQPRPSAA RDAPRIKWTK VRTASGQRQD LPILVAKDNV VRVAKSWQGR VSLPSYPRRR 120 ANATLLLGPL RASDSGLYRC QWRGIEDEQ DLVPLEVTGV VFHYRSARDR YALTFAEAQE 180 ACRLSSAIIA APRHLQAAFE DGFDNCDAGW LSDRTVRYPI TQSRPGCYGD RSSLPGVRSY 240 GRRNPQELYD VYCFARELGG EVFYVGPARR LTLAGARAQC RRQGAALASV GQLHLAWHEG 300 LDQCDPGWLA DGSVRYPIQT PRRRCGGPAP GVRTVYRFAN RTGFPSPAER FDAYCFRAHH 360 PTSQHGDLET PSSGDEGEIL SAEGPPVREL EPTLEEEEW TPDFQEPLVΞ SGEEETLILE 420 EKQESQQTLS PTPGDPMLAS WPTGEVWLST VAPSPSDMGA GTAASSHTEV APTDPMPRRR 480 GRFKGLNGRY FQQQEPEPGL QGGMEASAQP PTSEAAVNQM EPPLAMAVTE MLGSGQSRSP 540 WADLTNEVDM PGAGSAGGKS SPEPWLWPPT MVPPSISGHS RAPVLELEKA EGPΞARPATP 600 DLFWSPLEAT VSAPSPAPWE AFPVATSPDL PMMAMLRGPK EWMLPHPTPI STEANRVEAH 660 GEATATAPPS PAAETKVYSL PLSLTPTGQG GEAMPTTPEΞ PRADFRETGE TSPAQVNKAE 720 HSSSSPWPSV NRNVAVGFVP TETATEPTGL RGIPGSESGV FDTAESPTSG LQATVDEVQD 780 PWPSVYSKGL DASSPSAPLG SPGVFLVPKV TPNLEPWVAT DEGPTVNPMD STVTPAPSDA 840 SGIWEPGSQV FEEAESTTLS PQVALDTSIV TPLTTLEQGD KVGVPAMSTL GSSSSQPHPE 900 PEDQVETQGT SGASVPPHQS SPLGKPAVPP GTPTAASVGE SASVSSGEPT VPWDPSSTLL 960 PVTLGIEDFE LEVLAGSPGV ESFWEEVASG EEPALPGTPM NAGAEEVHSD PCENNPCLHG 1020 GTCNANGTMY GCSCDQGFAG ENCEIDIDDC LCSPCENGGT CIDEVNGFVC LCLPSYGGSF 1080 CEKDTEGCDR GWHKFQGHCY RYFAHRRAWE DAEKDCRRRS GHLTSVHSPE EHSFINSFGH 1140 ENTWIGLNDR IVERDFQWTD NTGLQFENWR ENQPDNFFAG GEDCWMVAH ESGRWNDVPC 1200 NYNLPYVCKK GTVLCGPPPA VENASLIGAR KAKNNVHATV RYQCNEGFAQ HHWTIRCRS 1260 NGKWDRPQIV CTKPRRSHRM RGHHHHHQHH HQHHHHKSRK ERRKHKKHPT EDWEKDEGNF 1320 C
Seq ID NO: 263 DNA sequence
Nucleic Acid Accession it: Eos sequence
Coding sequence: 7..2085
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I I I I I I
GCCGCGATGG CCAGCACCAG GAGTATCGAG CTGGAGCACT TTGAGGAACG GGACAAAAGG 60
CCGCGGCCGG GGTCGCGGAG AGGGGCCCCC AGCTCCTCCG GGGGCAGCAG CAGCTCGGGC 120
CCCAAGGGGA ACGGGCTCAT CCCCAGTCCG GCGCACAGTG CCCACTGCAG CTTCTACCGC 180
ACGCGGACCC TGCAGGCCCT CAGCTCGGAG AAGAAGGCCA AGAAGGCGCG CTTCTACCGG 240
AACGGGGACC GCTACTTCAA GGGCCTGGTG TTTGCCATCT CCAGCGACCG CTTCCGGTCC 300
TTCGATGCGC TCCTCATAGA GCTCACCCGC TCCCTGTCGG ACAACGTGAA CCTGCCCCAG 360
GGTGTCCGCA CTATCTACAC CATCGACGGC AGCCGGAAGG TCACCAGCCT GGACGAGCTG 420
CTGGAAGGTG AGAGTTACGT GTGTGCATCC AATGAACCAT TTCGTAAAGT CGATTACACC 480
AAAAATATTA ATCCAAACTG GTCTGTGAAC ATCAAGGGTG GGACATCCCG AGCGCTGGCT 540
GCTGCCTCCT CTGTGAAAAG TGAAGTAAAA GAAAGTAAAG ATTTCATCAA ACCCAAGTTA 600
GTGACTGTGA TTCGAAGTGG AGTGAAGCCT AGAAAAGCCG TGCGGATCCT TCTGAATAAA 660
AAGACTGCTC ATTCCTTTGA ACAAGTCTTA ACAGATATCA CCGAAGCCAT TAAACNAGCC 720
TCAGGAGTCG TCAAGAGGCT CTGCACCCTG GATGGAAAGC AGGTGAGAGT TACGTGTGTG 780
CATCTGCCAG ACTTTTTTGG TGATGACGAT GTTTTTATTG CATGTGGACC AGAAAAATTT 840
CGTTATGCCC AAGATGACTT TGTCCTGGAT CATAGTGAAT GTCGTGTCCT GAAGTCATCT 900
TATTCTCGAT CCTCAGCTGT TAAGTATTCT GGATCCAAAA GCCCTGGGCC CTCTCGACGC 960
AGCCAGATTT CTGCTCATGG CAGATCTTCT TCCAATGTAA ACGGTGGACC TGAGCTTGAC 1020
CGTTGCATAA GTCCTGAAGG TGTGAATGGA AACAGATGCT CTGAATCATC AACTCTTCTT 1080
GAGAAATACA AAATTGGAAA GGTCATTGGT GATGGCAATT TTGCAGTAGT CAAAGAGTGT 1140
ATAGACAGGT CCACTGGAAA GGAGTTTGCC CTAAAGATTA TAGACAAAGC CAAATGTTGT 1200
GGAAAGGAAC ACCTGATTGA GAATGAAGTG TCAATACTGC GCCGAGTGAA ACATCCCAAT 1260
ATCATTATGC TGGTCGAGGA GATGGAAACA GCAACTGAGC TCTTTCTGGT GATGGAATTG 1320
GTCAAAGGTG GAGATCTCTT TGATGCAATT ACTTCGTCGA CCAAGTACAC TGAGAGAGAT 1380
GGCAGTGCCA TGGTGTACAA CTTAGCCAAT GCCCTCAGGT ATCTCCATGG CCTCAGCATC 1440
GTGCACAGAG ACATCAAACC AGAGAATCTC TTGGTGTGTG AATATCCTGA TGGAACCAAG 1500
TCTTTGAAAC TGGGAGACTT TGGGCTTGCG ACTGTGGTAG AAGGCCCTTT ATACACAGTC 1560
TGTGGCACAC CCACTTATGT GGCTCCARAA ATCATTGCTG AAACTGGCTA TGGCCTGAAG 1620
GTGGACATTT GGGCAGCTGG TGTGATCACA TACATACTTC TCTGTGGATT CCCACCATTC 1680
CGAAGTGAGA ACAATCTCCA GGAAGATCTC TTCGACCAGA TCTTGGCTGG GAAGCTGGAG 1740
TTTCCGGCCC CCTACTGGGA TAACATCACG GACTCTGCCA AGGAATTAAT CAGTCAAATG 1800
CTTCAGGTAA ATGTTGAAGC TCGGTGTACC GCGGGACAAA TCCTGAGTCA CCCCTGGGTG 1860
TCAGATGATG CCTCCCAGGA GAATAACATG CAAGCTGAGG TGACAGGTAA ACTAAAACAG 1920
CACTTTAATA ATGCGCTCCC CAAACAGAAC AGCACTACCA CCGGGGTCTC CGTCATCATG 1980
GTGAGTGGAA GGCGGCAGGT CTGGCCTGAC TGCGGAGCCG GCCTTGAAGT TTTTGAATTA 2040
GGTAGCCGGG AGCTGCCCTC ACATGGAAGT TGGTGCCTTC CGTAGTCCTA TTTCATATGA 2100
AGATTGGCTT GGCATGTGGA GGGCACTCAT TCGGCAACTC CCAGGCTTTG GGCACTGTGT 2160
GGAGGGGCTT GTGTAGGGAC CAGCAGGCCT GGTGTGAGGG GTCCAGGCGT CAAGGAGCTC 2220
CTGGCTGGGC CCTCTGGGCA GCTGCTTCCA CTCTTGTCTC TGCCTTCTCA TCTAGAGAGA 2280
CTCCCAAGCC CTGGAGGGGT GTGTTGTGTT AGGAATTAAC TCCCTGCCTA CCCCAAGGCC 2340
TCAGAAATAG ATTATTAGAG ATGTGAATTA TTCTTTGAGA CTTGGGATAA GAAACAGCCA 2400
AAGCTAAACA TATTTCAGTT TTAAAAAATC AGTGTTTTAT AAAACACAGT TTGGGGCTTT 2460
TAAAGGTACA TAATCAAGGA AAAAAATATA TATTCATTTT TCAGGGTTGG TAACATTTTA 2520
TGAGATGTCA GTGACAACGA TGGCCTTATT TTTTTCAGCC TTTTCTTCTT CCAAAATGTT 2580
TCTTAAGGCA ACTCTCCTAA ATACATAAAC ACAACAAATT AAAATGAAAA GTGACATGAG 2640
AGTAAATGAA TCAAAAGGAA AAAACATTGA ACCAGAGGTG AGGGCAGCAC ACCCGCAGCA 2700
GCTGTCCAGG CCTGAGCCAA TGCAACCCTG GGCGGGAAGG CCAGCTCACC GTGAGCAGGT 2760
AGAAGCCAGC CAGCCACCCA GGCAGGGACC TTGGTTCTCC CCACACACTC CCAGGAGCAG 2820
GGAACAGGGG TGGAGTGGCC TTTCCCAGAG CTGGAGTTGG CTGCAGCAGC TTTCGAATCA 2880
GACCTGCCAA GGTGATGGGC GTCTGAGTTT CACATCTGGG CCCCCCGTGA CCCCACTGAG 2940
TCCTGACAGC TAAGGATGGG CCACCTCCAC AGCTCCGTCA CTCGTACTTG GGACAGGCCT 3000
CTCATCCTCT GGGAAGGTCC TCCTTGTTTC CTACCCAACT AGAAGGGAAA CAGTGGCATA 3060
TTCTCATGGT ACATGGTTGT CTGAAAGCCT TACCTAGGAA GACGCAGGGT CTAGATAGAA 3120
GCTATAAGGA AGCCACACAC ATAACCCACA TCCCCACACC CCCAACATCC CCCACACTCC 3180
CCACACCCCC CACACCCCCC ACATCCCCAC CATAATTACC CCCACCTCCA AATATCTCAT Seq ID NO: 264 Protein sequence Protein Accession #: Eos εequence
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MASTRSIELE HFEERDKRPR PGSRRGAPSS SGGSSSSGPK GNGLIPSPAH SAHCSFYRTR 60 TLQALSSEKK AKKARFYRNG DRYFKGLVFA ISSDRFRSFD ALLIELTRSL SDNVNLPQGV 120 RTIYTIDGSR KVTSLDELLE GESYVCASNE PFRKVDYTKN INPNWSVNIK GGTSRALAAA 180 SSVKSEVKES KDFIKPKLVT VIRSGVKPRK AVRILLNKKT AHSFEQVLTD ITEAIKXASG 240 WKRLCTLDG KQVRVTCVHL PDFFGDDDVF IACGPEKFRY AQDDFVLDHS ECRVLKSSYS 300 RSSAVKYSGS KSPGPSRRSQ ISAHGRSSSN VNGGPELDRC ISPEGVNGNR CSESSTLLEK 360 YKIGKVIGDG NFAWKECID RSTGKEFALK IIDKAKCCGK EHLIENEVSI LRRVKHPNII 420 MLVEEMETAT ELFLVMELVK GGDLFDAITS STKYTERDGS AMVYNLANAL RYLHGLSIVH 480 RDIKPENLLV CEYPDGTKSL KLGDFGLATV VEGPLYTVCG TPTYVAPXII AETGYGLKVD 540 IWAAGVITYI LLCGFPPFRS ENNLQEDLFD QILAGKLEFP APYWDNITDS AKELISQMLQ 600 VNVEARCTAG QILSHPWVSD DASQENNMQA EVTGKLKQHF NNALPKQNST TTGVSVIMVS 660 GRRQVWPDCG AGLEVFELGS RELPSHGSWC LP
Seq ID NO: 265 DNA sequence
Nucleic Acid Accession #: AB020684.1 Coding sequence: 1..1744
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CCCCCTTGTC ATTAATACAT TAAAAAGATT CAATCTTTAC CCTGAGGTAA TTTTGGCCAG 60
TTGGTACCGG ATTTATACCA AAATAATGGA CTTGATTGGT ATTCAAACCA AGATATGTTG 120
GACGGTTACC AGAGGAGAAG GACTCAGTCC TATTGAAAGC TGTGAAGGAT TGGGAGATCC 180
TGCTTGCTTT TATGTTGCTG TAATTTTTAT TTTAAATGGA CTAATGATGG CATTATTCTT 240
CATATATGGC ACATATTTAA GTGGCAGCCG ATTAGGAGGC CTGGTTACAG TGTTGTGCTT 300
CTTTTTCAAT CATGGAGAGT GTACCCGTGT AATGTGGACA CCACCTCTCC GTGAAAGCTT 360
CTCATATCCA TTTCTTGTTC TTCAGATGTT GCTAGTGACT CATATTCTCA GGGCTACAAA 420
ACTTTATAGA GGAAGCTTGA TTGCACTCTG CATTTCCAAT GTATTTTTCA TGCTTCCTTG 480
GCAGTTTGCT CAGTTTGTAC TTCTTACTCA GATTGCATCA TTATTTGCAG TATATGTTGT 540
CGGGTACATT GATATATGTA AATTACGGAA GATCATTTAT ATACACATGA TTTCTCTTGC 600
ACTTTGTTTT GTTTTGATGT TTGGGAACTC AATGTTATTA ACTTCTTATT ATGCTTCTTC 660
TTTGGTAATT ATTTGGGGTA TTCTGGCAAT GAAACCACAT TTCCTGAAAA TAAATGTATC 720
TGAACTTAGT TTATGGGTTA TTCAAGGATG TTTTTGGTTA TTTGGAACTG TCATACTTAA 780
ATACTTGACA TCTAAAATTT TTGGTATTGC AGATGACGCT CATATTGGCA ACTTACTAAC 840
ATCAAAATTC TTTAGTTATA AGGATTTTGA TACTTTATTG TATACCTGTG CAGCGGAGTT 900
TGACTTTATG GAAAAAGAGA CTCCACTGAG ATACACAAAG ACATTATTGC TTCCAGTTGT 960
TCTTGTAGTG TTTGTTGCTA TTGTTAGAAA GATTATTAGT GATATGTGGG GTGTCTTAGC 1020
TAAACAACAG ACACATGTAA GAAAACACCA GTTTGATCAT GGAGAGCTGG TTTACCATGC 1080
ATTGCAATTG TTAGCATATA CAGCCCTTGG TATTTTAATT ATGAGACTAA AACTCTTCTT 1140
GACACCACAC ATGTGTGTTA TGGCATCACT GATCTGCTCA AGACAGCTAT TTGGATGGCT 1200
CTTTTGCAAA GTACATCCTG GTGCTATTGT GTTTGCTATA TTAGCAGCAA TGTCAATACA 1260
AGGTTCAGCA AATCTGCAAA CCCAGTGGAA TATTGTAGGG GAGTTCAGCA ATTTGCCCCA 1320
AGAAGAACTT ATAGAATGGA TCAAATATAG TACTAAACCA GATGCAGTGT TTGCGGGTGC 1380
CATGCCCACG ATGGCAAGTG TTAAGCTCTC TGCACTTCGG CCCATTGTGA ATCATCCACA 1440
TTATGAAGAC GCAGGCTTGA GAGCCAGAAC AAAAATAGTA TACTCAATGT ATAGTCGGAA 1500
AGCAGCCGAA GAAGTGAAGC GAGAACTGAT AAAGTTAAAA GTGAACTATT ACATTCTAGA 1560
AGAGTCATGG TGTGTAAGAA GATCCAAGCC TGGTTGCAGT ATGCCTGAAA TTTGGGATGT 1620
AGAAGATCCT GCCAATGCTG GGAAAACTCC CTTATGTAAC CTCTTGGTGA AGGATTCCAA 1680
ACCTCACTTC ACCACTGTAT TCCAGAACAG TGTTTACAAA GTCCTAGAAG TTGTAAAAGA 1740
ATGACTGCTA CATGACCTGC TGCCTACGGA GAACTACATC TGTAATGGTT TTAATGTTTT 1800
GCTAAGTCAT GTGTTGTTCA TATCCCAAAA ACTTTTATAG GTAACTGTTT TCAAATAGAA 1860
AACGTTTTAT TTGGTCAATT TGAATGTCAT TCTAATTATA AAAATGACTT ACACCTTTAT 1920
CAATTGGTTA CTATTTCAAT GCACCCTTTA AAATTTGCTA TGCAAATGAG TATATGCTTG 1980
TACTTGACTT TAATATTTGT GCTAAAGTGA GCAAAGCTAC CTGTATAAAG AAAACACAGT 2040
GGGTTGTGAC AAGGATGACA TGAAAATACA GGACAATTCT GACAATGTAG GGGCTGATTT 2100
TATAGTGTAA GAACTATTAA TGCCCCTTGC TTCTTTTTTC TGCCTCTTGC TCTTGTCTTT 2160
TGGACATTTC AGTGATTGTA AGTTCTTCGG TCATGTCAGC CCCTGTCATC AACTTGAGTT 2220
ACAGTAGATG GGGCAGACAT GGAGTGTTTG CTATATAAAA CTATCTGTTT GTTTTACTTC 2280
CTTGTGCGCT TTTTGTTCTC TGTTCTCTTG TTAATGAAGC TTTTCCTGCC CATTATTAAT 2340
CCAAACTCTT GGACCTTGTG GTTAGGAAAT TCCCTTAACT TCCAGCCATA TGGCATTATC 2400
GTGTCTCTTT CTCTCTCTCT CTTGCTCTCT CTCTTCTCCT CTTCCCCATA TTTTCTGTCA 2460
AATAAGTACT GTTTACTCAT TTAGTTGCTT ATCAAGTACT TATTCTTGGT TTTAAAAAAA 2520
ATTAATGGTA ACTGTATTTT TCTCATTTTT AGCATTATTC AAATGTTTAT ATTTTAATAC 2580
CTTTAAACCA CTTTAAAGTT TTTTCATGTT TAATTATAGT TTTAAGAAAA ACTATTTTGA 2640
ACAACCCCAA ATATAGTGCA TCTAGAAACT AATGTATATT TGATTAGACA TCATTTATAG 2700
TGGAACAGTA GACTGTAGTA CATGGTAATT TTTCTTTTAC TATTAAGATA CAATAAAACA 2760
TGACTAATTT TGCTGTCAAA AATGTAAAGA ATAATGATAA ATGGAGTTTT TTATATTTTA 2820
CTTTTAAGAT TGCCTGTCTT TAATAAGACA AAGCCTTAAG CCTTATGTTA TAATTTTGGT 2880
TCTAAAAACC ATCATTTCAG TATAAGGAAT AAGTATATTT CGTCCTCCTC TTTAGTTTTT 2940
TTCTTCCTAT TTATTTTTAT TTTGAAAAAT TTCTACACCT TCTTTGAATT CCTTGTATGA 3000
ATTTTTGTTT CTTAGAAGTT AATTTGTGTG AAATGAGATT CTTCAAAACG ATGAAACCTC 3060
ATAGCTCTGA GAAAAGGTTT TAGGGTTTTA AATTCTAAGC AAAGCGTGAC TATGGCTGAC 3120
AGACTACACA TTTAATTATA CAGCTTCTCT TTCTTAACCA CAGGCAGATT AACCTCATTG 3180
TGGATTGTCC TTCAGACCTT AGTCCTCAGG CATGGTTTCT GGTGCCCACT CCTGGAAGCC 3240
GCTGTTCCCT TTCTACCTTC TTACCAGAGC CCAAGGGCAG GCCTGGTCCC GGGGAAGCAG 3300
CAGCTTGCTG ACATAAGTCA GCTGCAAAGG CTGAGGAGTG TGCCCTCAGA GAAGCACCGC 3360
CCCCCAGTCT TGTGCCAGCG CCTAGAGCCG CAGCTCCCAG GGATGCTCCT TCCCTGGAGG 3420
CAGCCCAGGA GAGGGACTCT GGCAGCGTTC TTCAGATTTG TGGCCACTGT TTCTCATTTG 3480
CTGGTTGACT GTTTTTATTT CTTAGGCTTT TGCTAGTTTT AGAAAATAGG GAAGCAGCCC 3540
TTGATTTGTG GATTAAAAGC AACATTTGAG CGATGATGCA CAACAGTCCA GGAAAATGGG 3600 CGGTGGACAC TTGAGGCTGA GGATGGGAGT TGACATGAGC AGGGAGAGGG AGGTGCGCGC 3660 TGCTTATCTG TGATTGTTGC TCACCTGAGT GTGGCTGATT GTGTACATCC AGCAGTTACA 3720 ATTTTTAAAA ATTATACTTT TACATTTATT TTATATTTTT CTCACCCCCA GTAATTTCCT 3780 TCCAAAGAAG TTCACATGTA ATAAGTAGAA ATTCTGTATA GGAAAAAAGC ATTAAAAATA 3840 CTATTATAAC TGCTTCATTT GCTGGGAACC ATTAAAAGTA ATATAAATTA GCTTTTTCCA 3900 GAAGGATCCT TTTGTAGCAG TGTTTATGAA TGTAACCCCC AGCAAAATAT GGCTATATAT 3960 TAGGGGAGCC AGTTTGGAGC AGAGGCCTGA AGGTCCCTGC TATGCAGCCG TGGCCACAGC 4020 TCGCAGCCCA AGCACTGTGG AGCATCCACA CCTTTGATGG CAATGCAGAT TGGTAGCAGG 4080 TTCCATAGGC GTACAAAACA GTATTAAAGC TCAGTGTTTT GCATATTGTT AGCATTTACA 4140 AATATTTTTG CTTTAGTATG AGGAAAGTAA GGATGGGCAA AGAAGCGATC AAAATAGCTA 4200 TTGCTACAAC ATTTTGGAAA ACAAAGTTGG GGCTGTATTT CTTTAAAAAG ATAAGCCTCT 4260 AAAAATGCTT GGCAAAAAAA ATATAGTGTT AAAATAGGCC AGTGATATTA ATGAGAAAAT 4320 GAAAGTATGT ATCAGGAATA AAGTGATATT GCATAGGAGT ATTGTATTTT TATGAATTTT 4380 ATGCCAGTTG TTTACATGTA CTATATATGT TAAATTAAAA AAAATCATGA GAAATG
Seq ID NO: 266 Protein εequence Protein Accession it: BAA74900.1
21 31 51
PLVINTLKRF NLYPEVILAS WYRIYTKIMD LIGIQTKICW TVTRGEGLSP IESCEGLGDP 60
ACFYVAVIFI LNGLMMALFF IYGTYLSGSR LGGLVTVLCF FFNHGECTRV MWTPPLRESF 120
SYPFLVLQML LVTHILRATK LYRGSLIALC ISNVFFMLPW QFAQFVLLTQ IASLFAVYW 180
GYIDICKLRK IIYIHMISLA LCFVLMFGNS MLLTSYYASS LVIIWGILAM KPHFLKINVS 240
ELSLWVIQGC FWLFGTVILK YLTSKIFGIA DDAHIGNLLT SKFFSYKDFD TLLYTCAAEF 300
DFMEKETPLR YTKTLLLPW LWFVAIVRK IISDMWGVLA KQQTHVRKHQ FDHGELVYHA 360
LQLLAYTALG ILIMRLKLFL TPHMCVMASL ICSRQLFGWL FCKVHPGAIV FAILAAMSIQ 420
GSANLQTQWN IVGEFSNLPQ EELIEWIKYS TKPDAVFAGA MPTMASVKLS ALRPIVNHPH 480
YEDAGLRART KIVYSMYSRK AAEEVKRELI KLKVNYYILE ESWCVRRSKP GCSMPEIWDV 540
EDPANAGKTP LCNLLVKDSK PHFTTVFQNS VYKVLEWKE
Seq ID NO: 267 DNA sequence
Nucleic Acid Accession ft: Coding sequence: 59..1600
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CTTCAAAGAA TATAGATGGT TTTGAAAAGT TCATGCTGTC CCTTCATTGA ATTTTAGAAT 60
GATTGAAGAT AGTGGGAAAA GAGGAAATAC CATGGCAGAA AGAAGACAGC TGTTTGCAGA 120
GATGAGGGCT CAAGATCTGG ATCGCATCCG ACTCTCCACC TACAGAACAG CATGCAAGCT 180
TAGGTTTGTT CAGAAGAAAT GCAATTTGCA CCTGGTGGAC ATATGGAATG TCATAGAAGC 240
ATTGCGGGAA AATGCTCTGA ACAACCTGGA CCCAAACACT GAACTCAACG TGTCCCGCTT 300
AGAGGCTGTG CTCTCCACTA TTTTTTACCA GCTCAACAAA CGGATGCCAA CCACTCACCA 360
AATCCATGTG GAGCAGTCCA TCAGCCTCCT CCTTAACTTC CTGCTTGCAG CGTTTGATCC 420
GGAAGGCCAT GGTAAAATTT CAGTATTTGC TGTCAAAATG GCTTTAGCCA CATTGTGTGG 480
AGGGAAGATC ATGGACAAAT TAAGATATAT TTTCTCAATG ATTTCTGACT CCAGTGGGGT 540
GATGGTTTAT GGACGATATG ACCAATTCCT TCGGGAAGTT CTCAAACTAC CCACGGAAGT 600
TTTGGAGGGT CCTTCATTTG GTTACACAGA ACAGTCAGCC AGATCCTCTT TCTCCCAACA 660
GAAAAAAGTC ACGTTAAATG GTTTCTTGGA CACGCTTATG TCAGATCCTC CCCCGCAGTG 720
TCTGGTCTGG TTGCCTCTTC TGCATCGACT AGCAAATGTG GAAAATGTCT TCCATCCGGT 780
TGAGTGTTCC TACTGCCACA GTGAGAGTAT GATGGGATTT CGCTACCGAT GCCAACAGTG 840
TCACAATTAC CAGCTCTGTC AGGACTGCTT CTGGAGGGGA CATGCCGGTG GTTCTCATAG 900
CAACCAGCAC CAAATGAAAG AGTACACGTC ATGGAAATCA CCTGCTAAGA AGCTGACTAA 960
TGCATTAAGC AAGTCCCTGA GCTGTGCTTC CAGCCGTGAA CCTTTGCACC CCATGTTCCC 1020
AGATCAGCCT GAGAAGCCAC TCAACTTGGC TCACATCGTT GATACTTGGC CTCCCAGACC 1080
TGTAACCAGC ATGAACGACA CCCTGTTCTC CCACTCTGTT CCCTCCTCAG GAAGTCCTTT 1140
TATTACCAGG AGCATGCTTG AGAGTTCAAA CCGGCTTGAT GAAGAACACA GGCTAATTGC 1200
CAGGTATGCG GCAAGGCTGG CAGCAGAGTC CTCTTCGTCT CAGCCACCTC AGCAGAGAAG 1260
TGCTCCTGAC ATCTCTTTCA CCATCGATGC GAATAAGCAG CAAAGGCAGC TGATTGCTGA 1320
GCTAGAAAAC AAGAACAGAG AAATCTTACA GGAGATCCAG AGACTTCGGC TAGAGCATGA 1380
ACAAGCTTCT CAGCCCACGC CAGAGAAGGC ACAGCAAAAC CCCACCCTGC TGGCAGAACT 1440
CCGGCTCCTC AGACAGCGCA AAGATGAGCT GGAACAGAGA ATGTCTGCTC TCCAGGAGAG 1500
CCGGAGAGAG CTAATGGTCC AGTTGGAGGG TCTCATGAAG CTACTAAAGG AAGAAGAACT 1560
GAAGCAGGGA GTAAGTTATG TCCCCTACTG CAGGTCTTAA CTAACAGTGG AGGGGCCTGC 1620
CGACCTGCGG TTTTCTCATT GCTTTTGCTC TAATGTATGT TCATGCTTCA GTTTGGAAAG 1680
AGAAAAAAGT CATACTAATT TGCTTCTTTT TCAATGTAGT GCTTGAATTG AGATATATAA 1740
ATTTAGCATT TTTTATAACT ATCACTACTA TCCACATCAA AAGAAGAACT ATGACATCTT 1800
TTAGAAAAGG GAACGAATTG TCATTTATTG GAAACATTTT AGATCCCCAG AGGTATAAGT 1860
TTCAAACCAG TCTTAGCTTT TCAAGTTGTT GATCAGACCC TTCTCTTAAC AGAGAGATAC 1920
CACAGTCACT AGAGATACCC TGAGGTTCAT GTCATCCCAA AACCCACAGC ACTCAGAAGC 1980
TAACCTCTAC ACCCACTCAC ACTGTGAGTA TTCAGTTCGG TTTCATTTTA CTGAAAACCT 2040
GTGAAACCTC TTTTTATAAA AATCAGGCAA TTAAATCCCT TTTCATCACA CAATTATTGA 2100
GCCTTGTTCC CCATGGCTCA CCAAAATGTG CTCAATTTTG TGAGAGAAAG ACTGTACTCC 2160
ATAACTGACT ATTCACGTCC CATCTTTTTG GCTCTTCCCC AAAGCAGAAT CCTTACTGTT 2220
GGTTGACAGT AATCTCTTTT TAAAAAGTAA CTCTCAGCTT TTTCCTTAGC ACCAGAGCCT 2280
TTCGGCTCCG GGAGACGAGA GGGTCATTAC ATACTTTTTT TTTTTTCTGG AAATAGGGGC 2340
ATTGTGACTT TATAGCCTAA ACTGGAGCTG TCTGAACCTG TGGTCAGGCT CAAGAGCCAG 2400
CAGGGGGAGC AGCAAACTC
Seq ID NO: 268 Protein sequence Protein Accession #: AAC50426.1
51 MIEDSGKRGN TMAERRQLFA EMRAQDLDRI RLSTYRTACK LRFVQKKCNL HLVDIWNVIE 60 ALRENALNNL DPNTELNVSR LEAVLΞTIFY QLNKRMPTTH QIHVEQSISL LLNFLLAAFD 120 PEGHGKISVF AVKMALATLC GGKIMDKLRY IFSMISDSSβ VMVYGRYDQF LREVLKLPTE 180 VLEGPSFGYT EQSARSCFSQ QKKVTLNGFL DTLMSDPPPQ CLVWLPLLHR LANVENVFHP 240 VECSYCHSES MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT 300 NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVDTWPPR PVTSMNDTLF SHSVPSSGSP 360 FITRSMLESS NRLDEEHRLI ARYAARLAAE SSSSQPPQQR SAPDISFTID ANKQQRQLIA 420 ELENKNREIL QEIQRLRLEH EQASQPTPEK AQQNPTLLAE LRLLRQRKDE LEQRMSALQE 480 SRRELMVQLE GLMKLLKEEE LKQGVSYVPY CRS
Seq ID NO: 269 DNA sequence Nucleic Acid Accession #: NM_ Coding sequence: 127..1278
11 21 31 41 51
I I I I I
AGTGGAGTGG GACAGGTATA TAAAGGAAGT ACAGGGCCTG GGGAAGAGGC CCTGTCTAGG 60 TAGCTGGCAC CAGGAGCCGT GGGCAAGGGA AGAGGCCACA CCCTGCCCTG CTCTGCTGCA 120 GCCAGAATGG GTGTGAAGGC GTCTCAAACA GGCTTTGTGG TCCTGGTGCT GCTCCAGTGC 180 TGCTCTGCAT ACAAACTGGT CTGCTACTAC ACCAGCTGGT CCCAGTACCG GGAAGGCGAT 240 GβGAGCTGCT TCCCAGATGC CCTTGACCGC TTCCTCTGTA CCCACATCAT CTACAGCTTT 300 GCCAATATAA GCAACGATCA CATCGACACC TGGGAGTGGA ATGATGTGAC GCTCTACGGC 360 ATGCTCAACA CACTCAAGAA CAGGAACCCC AACCTGAAGA CTCTCTTGTC TGTCGGAGGA 420 TGGAACTTTG GGTCTCAAAG ATTTTCCAAG ATAGCCTCCA ACACCCAGAG TCGCCGGACT 480 TTCATCAAGT CAGTACCGCC ATTCCTGCGC ACCCATGGCT TTGATGGGCT GGACCTTGCC 540 TGGCTCTACC CTGGACGGAG AGACAAACAG CATTTTACCA CCCTAATCAA GGAAATGAAG 600 GCCGAATTTA TAAAGGAAGC CCAGCCAGGG AAAAAGCAGC TCCTGCTCAG CGCAGCACTG 660 TCTGCGGGGA AGGTCACCAT TGACAGCAGC TATGACATTG CCAAGATATC CCAACACCTG 720 GATTTCATTA GCATCATGAC CTACGATTTT CATGGAGCCT GGCGTGGGAC CACAGGCCAT 780 CACAGTCCCC TGTTCCGAGG TCAGGAGGAT GCAAGTCCTG ACAGATTCAG CAACACTGAC 840 TATGCTGTGG GGTACATGTT GAGGCTGGGG GCTCCTGCCA GTAAGCTGGT GATGGGCATC 900 CCCACCTTCG GGAGGAGCTT CACTCTGGCT TCTTCTGAGA CTGGTGTTGG AGCCCCAATC 960 TCAGGACCGG GAATTCCAGG CCGGTTCACC AAGGAGGCAG GGACCCTTGC CTACTATGAG 1020 ATCTGTGACT TCCTCCGCGG AGCCACAGTC CATAGAACCC TCGGCCAGCA GGTCCCCTAT 1080 GCCACCAAGG GCAACCAGTG GGTAGGATAC GACGACCAGG AAAGCGTCAA AAGCAAGGTG 1140 CAGTACCTGA AGGATAGGCA GCTGGCAGGC GCCATGGTAT GGGCCCTGGA CCTGGATGAC 1200 TTCCAGGGCT CCTTCTGCGG CCAGGATCTG CGCTTCCCTC TCACCAATGC CATCAAGGAT 1260 GCACTCGCTG CAACGTAGCC CTCTGTTCTG CACACAGCAC GGGGGCCAAG GATGCCCCGT 1320 CCCCCTCTGG CTCCAGCTGG CCGGGAGCCT GATCACCTGC CCTGCTGAGT CCCAGGCTGA 1380 GCCTCAGTCT CCCTCCCTTG GGGCCTATGC AGAGGTCCAC AACACACAGA TTTGAGCTCA 1440 GCCCTGGTGG GCAGAGAGGT AGGGATGGGG CTGTGGGGAT AGTGAGGCAT CGCAATGTAA 1500 GACTCGGGAT TAGTACACAC TTGTTGATGA TTAATGGAAA TGTTTACAGA TCCCCAAGCC 1560 TGGCAAGGGA ATTTCTTCAA CTCCCTGCCC CCTAGCCCTC CTTATCAAAG GACACCATTT 1620 TGGCAAGCTC TATCACCAAG GAGCCAAACA TCCTACAAGA CACAGTGACC ATACTAATTA 1680 TACCCCCTGC AAAGCCAGCT TGAAACCTTC ACTTAGGAAC GTAATCGTGT CCCCTATCCT 1740 ACTTCCCCTT CCTAATTCCA CAGCTGCTCA ATAAAGTACA AGAGTTTAAC AGTGTGTTGG 1800 CGCTTTGCTT TGGTCTATCT TTGAGCGCCC ACTAGACCCA CTGGACTCAC CTCCCCCATC 1860 TCTTCTGGGT TCCTTCCTCT GAGCCTTGGG ACCCCTGAGC TTGCAGAGAT GAAGGCCGCC 1920 ATGTT
Seq ID NO: 270 Protein -sequence Protein Accession ft: NP 001267.1
11 21 31 41 51
I I I I I
MGVKASQTGF WLVLLQCCS AYKLVCYYTS WSQYREGDGS CFPDALDRFL CTHIIYSFAN 60 ISNDHIDTWE WNDVTLYGML NTLKNRNPNL KTLLSVGGWN FGSQRFSKIA SNTQSRRTFI 120 KSVPPFLRTH GFDGLDLAWL YPGRRDKQHF TTLIKEMKAE FIKEAQPGKK QLLLSAALSA 180 GKVTIDSSYD IAKISQHLDF ISIMTYDFHG AWRGTTGHHS PLFRGQEDAS PDRFSNTDYA 240 VGYMLRLGAP ASKLVMGIPT FGRSFTLASS ETGVGAPISG PGIPGRFTKE AGTLAYYEIC 300 DFLRGATVHR TLGQQVPYAT KGNQWVGYDD QESVKSKVQY LKDRQLAGAM VWALDLDDFQ 360 GSFCGQDLRF PLTNAIKDAL AAT
Seq ID NO: 271 DNA sequence Nucleic Acid Accession #: NM_006474. Coding sequence: 181..669
11 21 31 41 51
I I I I I
GCTGCCTAGG GTCTGGAAAG CTCGGGCACC CTCCCTCTCC GGGGCTCCTG CTCCCACCCC 60 TCCGGGCCCC CCACCGTCGC GCTCCTCCAG GCTGGGCCTG TGGCCGCGGT GCTTTTAATT 120 TTCCCCCAGC TCAGAATCTT GCTGCTCGGC CCCCAGGAGA GCAACAACTC AACGGGAACG 180 ATGTGGAAGG TGTCAGCTCT GCTCTTCGTT TTGGGAAGCG CGTCGCTCTG GGTCCTGGCA 240 GAAGGAGCCA GCACAGGCCA GCCAGAAGAT GACACTGAGA CTACAGGTTT GGAAGGCGGC 300 GTTGCCATGC CAGGTGCCGA AGATGATGTG GTGACTCCAG GAACCAGCGA AGACCGCTAT 360 AAGTCTGGCT TGACAACTCT GGTGGCAACA AGTGTCAACA GTGTAACAGG CATTCGCATC 420 GAGGATCTGC CAACTTCAGA AAGCACAGTC CACGCGCAAG AACAAAGTCC AAGCGCCACA 480 GCCTCAAACG TGGCCACCAG TCACTCCACG GAGAAAGTGG ATGGAGACAC ACAGACAACA 540 GTTGAGAAAG ATGGTTTGTC AACAGTGACC CTGGTTGGAA TCATAGTTGG GGTCTTACTA 600 GCCATCGGTT TCATTGGTGG AATCATCGTT GTGGTTATGC GAAAAATGTC GGGAAGGTAC 660 TCGCCCTAAA GAGCTGAAGG GTTACGCCCT GCTTGCCAAC GTGCTTTAAA AAAAGACCGT 720 TTCTGACTCT GTGGCCCTGT CCCTGAGCTC GTGGGGAGAA GATGACCCTG GGAACATTTβ 780 CGGGCCCATT CAGATTCCAC GGTGACTTTC CGTTTGCCAA ATTAACCGAG GAAAGACCTT 840 TCACCAGATT TGGTTCTTAA ACTTT
Seq ID NO 272 Protein sequence Protem Accession # NP 006465 1
11 21 31 41 51 I
MWKVSALLFV LGSASLWVLA EGASTGQPED DTETTGLEGG VAMPGAEDDV VTPGTSEDRY 60
KSGLTTLVAT SVNSVTGIRI EDLPTSESTV HAQEQSPSAT ASNVATSHST EKVDGDTQTT 120 VEKDGLSTVT LVGIIVGVLL AIGFIGGIIV WMRKMSGRY SP
Seq ID NO 273 DNA sequence
Nucleic Acid Accesεion ft CAT cluster
11 21 31 41 51
GCGGCCGCCA GCTTGCAAAG CCGAAGTCTG GCCGCGCTCT TCGACTCGCT GCGCCACGTC 60 CCCGGGGGTG CCGAGCCGGC GGGGGGTGAG GTGGCTGCGC CGGCGGCCGG GCTAGGAGGT 120 GCGGGCACTG GGGGCGCGGG AGGGGACGTG GCAGGCCCCG CGGGGGCCAC GGCGATCCCA 180 GGGGCCAGGA AGGTCCCGCT GCGGGCACGC AATCTGCCTC CGTCCTTCTT CACGGAGCCG 240 TCCCGGGCAG GCGGCGGCGG GTGTGGCCCG TCGGGGCCGG ACGTGAGCTT GGGCGACCTG 300 GAGAAGGGCG CGGAGGCCGT GGAGTTCTTT GAGCTGCTGG GGCCCGACTA CGGCGCCGGC 360 ACGGAGGCGβ CAGTCTTGCT TGCCGCCGAG CCTCTCGACG TGTTCCCCGC CGGAGCCTCC 420 GTACTGCGGG GACCCCCGGA GCTGGAGCCC GGCCTCTTTG AGCCGCCGCC GGCAGTGGTG 480 GGAAACCTAC TGTACCCCGA GCCCTGGAGC GTCCCGGGCT GCTCCCCGAC CAAAAAGAGC 540 CCCTTGACTG CCCTCCGCGG CGGGTTGACC TTGAACGAGC CCTTGAGCCC CCTGTACCCC 600 GCCGCTGCGA ATTTCTCCCG GCGGGGAGGA CGGGCCGGGC CATTTGGCTT CTTTCGCCCC 660 CTTCTTTCCA GACTGCGCTT TGC
Seq ID NO 274 DNA sequence
Nucleic Acid Accesεion # Eos sequence
11 21 31 41 51
I I I I I
CAAAGAGGCC GGGCTCCAGC TCCGGGGGTC CCCGCAGTAC GGAGGCTCCG GCGGGGAACA 60 CGTCGAGAGG CTCGGCGGCA AGCAAGACTG CCGCCTCCGT GCCGGCGCCG TAGTCGGGCC 120 CCAGCAGCTC AAAGAACTCC ACGGCCTCCG CGCCCTTCTC CAGGTCGCCC AAGCTCACGT 180 CCGGCCCCGA CGGGCCACAC CCGCCGCCGC CTGCCCGGGA CGGCTCCGTG AAGAAGGACG 240 GAGGCAGATT GCGTGCCCGC AGCGGGACCT TCCTGGCCCC TGGGATCGCC GTGGCCCCCG 300 CGGGGCCTGC CAGGTCCCCT CCCGCGCCCC CAGTGCCCGC ACCTCCTAGC CCGGCCGCCG 360 GCGCAGCCAC CTCACCCCCC GCCGGCTCGβ CACCCCCGGG GACGTGGCGC AGCGAGTCGA 420 AGAGCGCGGC CAGACTTCGG CTTTGCAAGC TGGCGGCCGC
Seq ID NO 275 DNA sequence Nucleic Acid Accesεion # NM_001118 1 Coding sequence 74 1651
11 21 31 41 51
I I I I I
AGCCCAGAGA CACATTGGGG CTGACCTGCC GCTGCTGTCA GTGGGAGGCC AGTGGTGCTG 60 GCCAAGAAGT GTCATGGCTG GTGTCGTGCA CGTTTCCCTG GCTGCTCACT GCGGGGCCTG 120 TCCGTGGGGC CGGGGCAGAC TCCGCAAAGG ACGCGCAGCC TGCAAGTCCG CGGCCCAGAG 180 ACACATTGGG GCTGACCTGC CGCTGCTGTC AGTGGGAGGC CAGTGGTGCT GGCCAAGAAG 240 TGTCATGGCT GGTGTCGTGC ACGTTTCCCT GGCTGCTCTC CTCCTGCTGC CTATGGCCCC 300 TGCCATGCAT TCTGACTGCA TCTTCAAGAA GGAGCAAGCC ATGTGCCTGG AGAAGATCCA 360 GAGGGCCAAT GAGCTGATGG GCTTCAATGA TTCCTCTCCA GGCTGTCCTG GGATGTGGGA 420 CAACATCACG TGTTGGAAGC CCGCCCATGT GGCTGAGATG GTCCTGGTCA GCTGCCCTGA 480 GCTCTTCCGA ATCTTCAACC CAGACCAAGT CTGGGAGACC GAAACCATTG GAGAGTCTGA 540 TTTTGGTGAC AGTAACTCCT TAGATCTCTC AGACATGGGA GTGGTGAGCC GGAACTGCAC 600 GGAGGATGGC TGGTCGGAAC CCTTCCCTCA TTACTTTGAT GCCTGTGGGT TTGATGAATA 660 TGAATCTGAG ACTGGGGACC AGGATTATTA CTACCTGTCA GTGAAGGCCC TCTACACGGT 720 TGGCTACAGC ACATCCCTCG TCACCCTCAC CACTGCCATG GTCATCCTTT GTCGCTTCCG 780 GAAGCTGCAC TGCACACGCA ACTTCATCCA CATGAACCTG TTTGTGTCGT TCATGCTGAG 840 GGCGATCTCC GTCTTCATCA AAGACTGGAT TCTGTATGCG GAGCAGGACA GCAACCACTG 900 CTTCATCTCC ACTGTGGAAT GTAAGGCCGT CATGGTTTTC TTCCACTACT GTGTTGTGTC 960 CAACTACTTC TGGCTGTTCA TCGAGGGCCT GTACCTCTTC ACTCTGCTGG TGGAGACCTT 1020 CTTCCCTGAA AGGAGATACT TCTACTGGTA CACCATCATT GGCTGGGGGA CCCCAACTGT 1080 GTGTGTGACA GTGTGGGCTA CGCTGAGACT CTACTTTGAT GACACAGGCT GCTGGGATAT 1140 GAATGACAGC ACAGCTCTGT GGTGGGTGAT CAAAGGCCCT GTGGTTGGCT CTATCATGGT 1200 TAACTTTGTG CTTTTTATTG GCATTATCGT CATCCTTGTG CAGAAACTTC AGTCTCCAGA 1260 CATGGGAGGC AATGAGTCCA GCATCTACTT GCGACTGGCC CGGTCCACCC TGCTGCTCAT 1320 CCCACTATTC GGAATCCACT ACACAGTATT TGCCTTCTCC CCAGAGAATG TCAGCAAAAG 1380 GGAAAGACTC GTGTTTGAGC TGGGGCTGGβ CTCCTTCCAG GGCTTTGTGG TGGCTGTTCT 1440 CTACTGTTTT CTGAATGGTG AGGTACAAGC GGAGATCAAG CGAAAATGGC GAAGCTGGAA 1500 GGTGAACCGT TACTTCGCTG TGGACTTCAA GCACCGACAC CCGTCTCTGG CCAGCAGTGG 1560 GGTGAATGGG GGCACCCAGC TCTCCATCCT GAGCAAGAGC AGCTCCCAAA TCCGCATGTC 1620 TGGCCTCCCT GCTGACAATC TGGCCACCTG AGCCATGCTC CCCT
Seq ID NO 276 Protein sequence Protem Accession ft NP 001109 1
1 11 21 31 41 51
I I I I I I
MAGWHVSLA AHCGACPWGR GRLRKGRAAC KSAAQRHIGA DLPLLSVGGQ WCWPRSVMAG WHVSLAALL LLPMAPAMHS DCIFKKEQAM CLEKIQRANE LMGFNDSSPG CPGMWDNITC 120
WKPAHVGEMV LVSCPELFRI FNPDQVWETE TIGESDFGDS NSLDLSDMGV VSRNCTEDGW 180
SEPFPHYFDA CGFDEYESET GDQDYYYLSV KALYTVGYST SLVTLTTAMV ILCRFRKLHC 240
TRNFIHMNLF VSFMLRAISV FIKDWILYAE QDSNHCFIST VECKAVMVFF HYCWSNYFW 300
LFIEGLYLFT LLVETFFPER RYFYWYTIIG WGTPTVCVTV WATLRLYFDD TGCWDMNDST 360
ALWWVIKGPV VGSIMVNFVL FIGIIVILVQ KLQSPDMGGN ESSIYLRLAR STLLLIPLFG 420
IHYTVFAFSP ENVSKRERLV FELGLGSFQG FWAVLYCFL NGEVQAEIKR KWRSWKVNRY 480
FAVDFKHRHP SLASSGVNGG TQLSILSKSS SQIRMSGLPA DNLAT
Seq ID NO: 277 DNA sequence
Nucleic Acid Accession #: NM_004000.1 Coding sequence: 36..1193
11 21 31 41 51
I I I I I
AGAAGAAGCT GGCCAAGGAT ATGGGAGCAA CCACCATGGA CCAGAAGTCT CTCTGGGCAG 60 GTGTAGTGGT CTTGCTGCTT CTCCAGGGAG GATCTGCCTA CAAACTGGTT TGCTACTTTA 120 CCAACTGGTC CCAGGACCGG CAGGAACCAG GAAAATTCAC CCCTGAGAAT ATTGACCCCT 180 TCCTATGGTC TCATCTCATC TATTCATTCG CCAGCATCGA AAACAACAAG GTTATCATCA 240 AGGACAAGAG TGAAGTGATG CTCTACCAGA CCATCAACAG TCTCAAAACC AAGAATCCCA 300 AACTGAAAAT TCTCTTGTCC ATTGGAGGGT ACCTGTTTGG TTCCAAAGGG TTCCACCCTA 360 TGGTGGATTC TTCTACATCA CGCTTGGAAT TCATTAACTC CATAATCCTG TTTCTGAGGA 420 ACCATAACTT TGATGGACTG GATGTAAGCT GGATCTACCC AGATCAGAAA GAAAACACTC 480 ATTTCACTGT GCTGATTCAT GAGTTAGCAG AAGCCTTTCA GAAGGACTTC ACAAAATCCA 540 CCAAGGAAAG GCTTCTCTTG ACTGCGGGCG TATCTGCAGG GAGGCAAATG ATTGATAACA 600 GCTATCAAGT TGAGAAACTG GCAAAAGATC TGGATTTCAT CAACCTCCTG TCCTTTGACT 660 TCCATGGGTC TTGGGAAAAG CCCCTTATCA CTGGCCACAA CAGCCCTCTG AGCAAGGGGT 720 GGCAGGACAG AGGGCCAAGC TCCTACTACA ATGTGGAATA TGCTGTGGGG TACTGGATAC 780 ATAAGGGAAT GCCATCAGAG AAGGTGGTCA TGGGCATCCC CACATATGCG CACTCCTTCA 840 CACTGGCCTC TGCAGAAACC ACCGTGGGGG CCCCTGCCTC TGGCCCTGGA GCTGCTGGAC 900 CCATCACAGA GTCTTCAGGC TTCCTGGCCT ATTATGAGAT CTGCCAGTTC CTGAAAGGAG 960 CCAAGATCAC GCGCCTCCAG GATCAGCAGG TTCCCTACGC AGTCAAGGGG AACCAGTGGG 1020 TGGGCTATGA TGATGTGAAG AGTATGGAGA CCAAGGTTCA GTTCTTAAAG AATTTAAACC 1080 TGGGAGGAGC CATGATCTGG TCTATTGACA TGGATGACTT CACTGGCAAA TCCTGCAACC 1140 AGGGCCCTTA CCCTCTTGTC CAAGCAGTCA AGAGAAGCCT TGGCTCCTTG TGAAGGATTA 1200 ACTTACAGAG AAGCAGGCAA GATGACCTTG CTGCCTGGGG CCTGCTCTCT CCCAGGAATT 1260 CTCATGTGGβ ATTCCCCTTG CCAGGCTGGC CTTTGGATCT CTCTTCCAAG CCTTTCCTGA 1320 CTTCCTCTTA GATCATAGAT TGGACCTGGT TTTGTTTTCC TGCAGCTGTT GACTTGTTGC 1380 CCTGAAGTAC AATAAAAAAA ATTCATTTTG CTCCAGTA
Seq ID NO: 278 Protein sequence Protein Accession #: NP 003991.1
11 21 31 41 51
I I I I I
MDQKSLWAGV W 1LLLLQGGS AYKLVCYFTN WSQDRQEPGK FTPENIDPFL CSHLIYSFAS 60 IENNKVIIKD KSEVMLYQTI NSLKTKNPKL KILLSIGGYL FGSKGFHPMV DSSTSRLEFI 120 NSIILFLRNH NFDGLDVSWI YPDQKENTHF TVLIHELAEA FQKDFTKSTK ERLLLTAGVS 180 AGRQMIDNSY QVEKLAKDLD FINLLSFDFH GSWEKPLITG HNSPLSKGWQ DRGPSSYYNV 240 EYAVGYWIHK GMPSEKWMG IPTYGHSFTL ASAETTVGAP ASGPGAAGPI TESSGFLAYY 300 EICQFLKGAK ITRLQDQQVP YAVKGNQWVG YDDVKSMETK VQFLKNLNLG GAMIWSIDMD 360 DFTGKSCNQG PYPLVQAVKR SLGSL
Seq ID NO: 279 DNA sequence
Nucleic Acid Accession ft: NM_015166.1
Coding sequence: 116..1249
11 21 31 41 51
I I I I I
TGCTGGAAGT CCCTCACCCA GAGACCAGTG CTCCCAACGG CAGAGCAGCG GGGGAGATAA 60 AGAACTGGTG ACACGTGGCT GTACATTCAG CACAGCTGTG GTGTCCCCAA GTGCCATGAC 120 CCAGGAGCCA TTCAGAGAGG AGCTGGCCTA TGACCGGATG CCCACGCTGG AGCGGGGCCG 180 GCAAGACCCC GCCAGCTATG CCCCAGACGC GAAGCCGAGC GACCTGCAGC TGTCGAAGAG 240 ACTGCCCCCC TGCTTCAGCC ACAAGACGTG GGTCTTCTCT GTGCTGATGG GGAGCTGCCT 300 CCTGGTGACC TCGGGGTTTT CGCTGTACCT GGGGAACGTG TTCCCGGCTG AGATGGATTA 360 CTTGCGCTGT GCTGCAGGCT CTTGCATCCC CTCGGCAATT GTGAGCTTCA CCGTCTCCAG 420 GAGGAACGCC AATGTGATTC CCAACTTTCA GATATTGTTT GTTTCCACGT TTGCTGTGAC 480 CACTACGTGT TTAATTTGGT TTGGATGCAA ACTAGTCCTG AACCCATCAG CAATAAACAT 540 CAACTTCAAC CTCATCCTGC TGCTCCTGCT GGAGCTGCTC ATGGCGGCCA CGGTGATCAT 600 CGCTGCACGG TCCAGCGAGG AGGACTGCAA GAAAAAGAAG GGCTCCATGT CTGACAGCGC 660 CAACATTCTG GACGAAGTGC CATTTCCTGC TCGGGTCCTG AAATCTTACT CAGTCGTCGA 720 GGTAATCGCA GGCATCTCTG CCGTCCTCGG GGGGATCATT GCCCTGAACG TGGATGACTC 780 AGTTTCAGGC CCACACCTCT CAGTGACGTT CTTTTGGATC CTAGTGGCCT GCTTTCCAAG 840 TGCCATTGCC AGTCATGTGG CAGCAGAGTG TCCCAGCAAG TGTCTGGTGG AGGTCCTGAT 900 TGCCATAAGC AGCCTCACGT CTCCGCTGCT GTTCACAGCC TCTGGATATC TGTCATTCAG 960 CATCATGAGA ATCGTGGAGA TGTTTAAGGA TTACCCGCCA GCCATAAAAC CATCCTACGA 1020 TGTGCTGCTG CTGCTGCTGC TGCTAGTGCT CCTGCTGCAG GCCGGCCTCA ACACGGGCAC 1080 CGCCATCCAG TGCGTGCGCT TCAAGGTCAG TGCAAGGCTG CAGGGTGCAT CCTGGGACAC 1140 CCAGAACGGC CCGCAGGAGC GCCTGGCTGG GGAGGTGGCC AGGAGCCCCC TGAAGGAGTT 1200 CGACAAGGAG AAAGCCTGGA GAGCCGTCGT GGTGCAAATG GCCCAGTGAC CCCCAGACGC 1260 GGAAACCGGG TGGCAGCGCC CAGCCTGGCC CCAAGCATGG AAACGCACAA CCCCTAATCG 1320 CCCTGAGCTA CTGCTTCTAA CACCTCTTTT CCCTTGTGTG AGGGCAAACC AGGCTGCAGG 1380 TGGGGTTTTC ACTTCCTAGG GTAGTTTAAT TTTAAAATAG GCCAATGTTG GCTAGTCTGT 1440 GCCTCAGTGA GATCAGTCAG CTCCGAGTGG CTCCCGTGTC GTAAGAGCAG GAGCATGGCC 1500 GCAACTTCCC AGGCCGAGGA AGGGCCCCCG GCTCGGCCTC TTGAGAGCCC CACCCCTGAA 1560 CTGGCCCCAG CTCCTCTTCC TGCCTCTCTC ATGGCTTGGG CTGGAGTGGG CTCTCTGGAC 1620 CTGACCAGAC TGTGGGTCCC TGCGTCTCCT GCCCACTCTG ACCGGGCTTC CTCCCTCCAC 1680 GCTTAGGGTC TGTCCCGGGT ACTCAGTCAG CCCAGTGGGA TCTTACCCAC TTCCCTGCAA 1740 GGTGCACCTG CCCCAGGCTC AGGCTGCCCA GCGGCTCTTC CTGGACAGTG AGAGCAGGGC 1800 TTGGCGCCTC TGTCCTGGCC CGGGAGCCGC AGGGGCCCCT CCTCCAGAGC CTGGGCGCAA 1860 GCGACACAGG CTGCCGCTGC TCTCCCAGGT GAAATCCACA CCAGTCCACG CCGGGTCGCC 1920 TGCCCTGTCT CCCTACTTAG ACCCAGTCAT TCTAGAGGGA TCCACCGCCA CACTGGCCGG 1980 CCCACGTCCT GGGTGCTGTC ATGCCCAGCT TGGAGTGCCA CGTGGCCGCT GCCCACGTCC 2040 CGGGCACTGT CATGCCCAGC TTGGAGTGCC ACATGGCCGC TGCCCACGTC CCGGGCACTG 2100 TCATGCCCAG CTTGGAGTGC CACGTGGCCG CTGCTGTGAC AGGCAGTGTT CTTGGGGGTG 2160 GGGCTGCATC CAAGGCTTTG TAAACCGGCT GGACCACGTC TCCCTGGCCC CAGTGACCGG 2220 GGGAAGCTGA GCCCCTCCCT CCTGTGTTTG CTCCCATTAC TCAAAATGCA GGACAGATCA 2280 GGTCAGAGCC CAGGAATTCT CACAGGTTCA CCCAGCGCCC TCTACCTCCT AGCAAGTACT 2340 TTGTCTTGAT CCTCACTGAG AAGGCCCCAG GGCAGCGGTC TTCTCCATCT CCGCTGTTTT 2400 GGGGTCTTAG GGTACAGCCC AGGCGGTCAC TGCCCACCTG CCAGGCTGCA GGGACAGTTG 2460 GGTGTGAGAA TAACACTGGC TTTGGGTAGT GCCATGGCCA GGAGTGGGTT TCCCTGCGTC 2520 TCCTCGTCCC GAGGGCGCCT GGGTCCTCCC AGCTGACGGC AGTAAATCCA CAGTGAGTTG 2580 GGGCGACTGT GAAACTGGAA TGCTGTTACT TTGATAATTA CTTTCCAGCA GGTGTTTTCC 2640 TTCACAATGG TTTTGTTTCT TTCCTTCTGA TCTGAGAAGA CATGAACGTT TTCTCTTCAC 2700 CGCCGTGGGG TGTATTGACT GGTCCCCCAT GGGCTGCTGG AAAGGCCCGG AGATGCATCT 2760 GTGGCCTGGG GCCATCAAGA TCAAAGAACC AGGAGGCCTG GGAGATGCAG CTGGATGGGG 2820 CGGCCTGCAG ACCCTGCCAG GGGGTTTGAG GACCCTCCCA GGTTTCCCAC TGCGGAACAG 2880 GAGTGACTCT GGCTGCCAAG ATACCTTCAT GGTGTTCATG ACAAGTGGAA TCATTATTTT 2940 CAACCATTGA AGGGGGATGG AGGCAAGACA CCTTCCCAGC TGCTCCTAGA GGGGACAAGC 3000 CAGGCCCTCT CTGCAGTCCT CGGCAGCTCC GGAAGGACAC AGTCAGGGGC CGGGCAAACA 3060 CTTTGGCCAC AGCCCCAAAC AAGCGCCACC GTGGGAGAGG AGAGGCTGCT GTCACTGGTA 3120 CCGGATGCAG ACCCCACCCT GTCTGCAGGC CACCCCCACC TCCCTGCAGC TTTGAGGCTG 3180 GCGGGGTCTG CTCCTGGGAA TGGGGTGGGA GCCACAGGGA CGACCCGGGG CGGGCTGATG 3240 TCTTCTTGGG GGCAGACCAG AGAGCTCAAG TTTCAGAGTC AGAATTAGGC ACTTGGAACG 3300 TTTTTGCTGG CTTGCACTTT CTTATTTTCT TATTTTAGAG CGCTTAAAAA ATCCGGAAAA 3360 ATGGGGTTTA AAAGAACTGT CTCTTTCAGT CTACATTTTT GTTTAATACG CTTGAGCAAT 3420 AAACGCTGAC TTGCAGACGT G
Seq ID NO: 280 Protein sequence Protein Accession ft: NP 055981.1
21 31
MTQEPFREEL AYDRMPTLER GRQDPASYAP DAKPSDLQLS KRLPPCFSHK TWVFSVLMGS 60
CLLVTSGFSL YLGNVFPAEM DYLRCAAGSC IPSAIVSFTV SRRNANVIPN FQILFVSTFA 120
VTTTCLIWFG CKLVLNPSAI NINFNLILLL LLELLMAATV IIAARSSEED CKKKKGSMSD 180
SANILDEVPF PARVLKSYSV VEVIAGISAV LGGIIALNVD DSVSGPHLSV TFFWILVACF 240
PSAIASHVAA ECPSKCLVEV LIAISSLTSP LLFTASGYLS FSIMRIVEMF KDYPPAIKPS 300
YDVLLLLLLL VLLLQAGLNT GTAIQCVRFK VSARLQGASW DTQNGPQERL AGEVARSPLK 360
EFDKEKAWRA VWQMAQ
Seq ID NO: 281 DNA sequence
Nucleic Acid Accession ft : NM_004518.1 Coding sequence : 43 . -2577
11 21 31 41 51
I I I I
GCTGAGCCTG AGCCCGACCC GGGGCGCCTC CCGCCAGGCA CCATGGTGCA GAAGTCGCGC 60 AACGGCGGCG TATACCCCGG CCCGAGCGGG GAGAAGAAGC TGAAGGTGGG CTTCGTGGGG 120 CTGGACCCCG GCGCGCCCGA CTCCACCCGG GACGGGGCGC TGCTGATCGC CGGCTCCGAG 180 GCCCCCAAGC GCGGCAGCAT CCTCAGCAAA CCTCGCGCGG GCGGCGCGGG CGCCGGGAAG 240 CCCCCCAAGC GCAACGCCTT CTACCGCAAG CTGCAGAATT TCCTCTACAA CGTGCTGGAG 300 CGGCCGCGCG GCTGGGCGTT CATCTACCAC GCCTACGTGT TCCTCCTGGT TTTCTCCTGC 360 CTCGTGCTGT CTGTGTTTTC CACCATCAAG GAGTATGAGA AGAGCTCGGA GGGGGCCCTC 420 TACATCCTGG AAATCGTGAC TATCGTGGTG TTTGGCGTGG AGTACTTCGT GCGGATCTGG 480 GCCGCAGGCT GCTGCTGCCG GTACCGTGGC TGGAGGGGGC GGCTCAAGTT TGCCCGGAAA 540 CCGTTCTGTG TGATTGACAT CATGGTGCTC ATCGCCTCCA TTGCGGTGCT GGCCGCCGGC 600 TCCCAGGGCA ACGTCTTTGC CACATCTGCG CTCCGGAGCC TGCGCTTCCT GCAGATTCTG 660 CGGATGATCC GCATGGACCG GCGGGGAGGC ACCTGGAAGC TGCTGGGCTC TGTGGTCTAT 720 GCCCACAGCA AGGAGCTGGT CACTGCCTGG TACATCGGCT TCCTTTGTCT CATCCTGGCC 780 TCGTTCCTGG TGTACTTGGC AGAGAAGGGG GAGAACGACC ACTTTGACAC CTACGCGGAT 840 GCACTCTGGT GGGGCCTGAT CACGCTGACC ACCATTGGCT ACGGGGACAA GTACCCCCAG 900 ACCTGGAACG GCAGGCTCCT TGCGGCAACC TTCACCCTCA TCGGTGTCTC CTTCTTCGGG 960 CTGCCTGCAG GCATCTTGGG GTCTGGGTTT GCCCTGAAGG TTCAGGAGCA GCACAGGCAG 1020 AAGCACTTTG AGAAGAGGCG GAACCCGGCA GCAGGCCTGA TCCAGTCGGC CTGGAGATTC 1080 TACGCCACCA ACCTCTCGCG CACAGACCTG CACTCCACGT GGCAGTACTA CGAGCGAACG 1140 GTCACCGTGC CCATGTACAG ACTTATCCCC CCGCTGAACC AGCTGGAGCT GCTGAGGAAC 1200 CTCAAGAGTA AATCTGGACT CGCTTTCAGG AAGGACCCCC CGCCGGAGCC GTCTCCAAGC 1260 CAGAAGGTCA GTTTGAAAGA TCGTGTCTTC TCCAGCCCCC GAGGCGTGGC TGCCAAGGGG 1320 AAGGGGTCCC CGCAGGCCCA GACTGTGAGG CGGTCACCCA GCGCCGACCA GAGCGTCGAG 1380 GACAGCCCCA GCAAGGTGCC CAAGAGCTGG AGCTTCGGGG ACCGCAGCCG GGCACGCCAG 1440 GCTTTCCGCA TCAAGGGTGC CGCGTCACGG CAGAACTCAG AAGAAGCAAG CCTCCCCGGA 1500 GAGGACATTG TGGATGACAA GAGCTGCCCC TGCGAGTTTG TGACCGAGGA CCTGACCCCG 1560 GGCCTCAAAG TCAGCATCAG AGCCGTGTGT GTCATGCGGT TCCTGGTGTC CAAGCGGAAG 1620 TTCAAGGAGA GCCTGCGGCC CTACGACGTG ATGGACGTCA TCGAGCAGTA CTCAGCCGGC 1680 CACCTGGACA TGCTGTCCCG AATTAAGAGC CTGCAGTCCA GAGTGGACCA GATCGTGGGG 1740 CGGGGCCCAG CGATCACGGA CAAGGACCGC ACCAAGGGCC CGGCCGAGGC GGAGCTGCCC 1800 GAGGACCCCA GCATGATGGG ACGGCTCGGG AAGGTGGAGA AGCAGGTCTT GTCCATGGAG 1860 AAGAAGCTGG ACTTCCTGGT GAATATCTAC ATGCAGCGGA TGGGCATCCC CCCGACAGAG 1920 ACCGAGGCCT ACTTTGGGGC CAAAGAGCCG GAGCCGGCGC CGCCGTACCA CAGCCCGGAA 1980 GACAGCCGGG AGCATGTCGA CAGGCACGGC TGCATTGTCA AGATCGTGCG CTCCAGCAGC 2040 TCCACGGGCC AGAAGAACTT CTCGGCGCCC CCGGCCGCGC CCCCTGTCCA GTGTCCGCCC 2100 TCCACCTCCT GGCAGCCACA GAGCCACCCG CGCCAGGGCC ACGGCACCTC CCCCGTGGGG 2160 GACCACGGCT CCCTGGTGCG CATCCCGCCG CCGCCTGCCC ACGAGCGGTC GCTGTCCGCC 2220 TACGGCGGGG GCAACCGCGC CAGCATGGAG TTCCTGCGGC AGGAGGACAC CCCGGGCTGC 2280 AGGCCCCCCG AGGGGACCCT GCGGGACAGC GACACGTCCA TCTCCATCCC GTCCGTGGAC 2340 CACGAGGAGC TGGAGCGTTC CTTCAGCGGC TTCAGCATCT CCCAGTCCAA GGAGAACCTG 2400 GATGCTCTCA ACAGCTGCTA CGCGGCCGTG GCGCCTTGTG CCAAAGTCAG GCCCTACATT 2460 GCGGAGGGAG AGTCAGACAC CGACTCCGAC CTCTGTACCC CGTGCGGGCC CCCGCCACGC 2520 TCGGCCACCG GCGAGGGTCC CTTTGGTGAC GTGGGCTGGG CCGGGCCCAG GAAGTGAGGC 2580 GGCGCTGGGC CAGTGGACCC GCCCGCGGCC CTCCTCAGCA CGGTGCCTCC GAGGTTTTGA 2640 GGCGGGAACC CTCTGGGGCC CTTTTCTTAC AGTAACTGAG TGTGGCGGGA AGGGTGGGCC 2700 CTGGAGGGGC CCATGTGGGC TGAAGGATGG GGGCTCCTGG CAGTGACCTT TTACAAAAGT 2760 TATTTTCCAA CAGGGCACTC CCAGGCCCTG TCGCCATTGA GGTGCCTCCG CTGGGCTGTC 2820 TCCTCACCCC TCCCTGTGCT GGAGCCTGTC CCAAAAAGGT GCCAACTGGG AGGCCTCGGA 2880 AGCCACTGTC CAGGCTCCCA CTGCCTGTCT GCTCTGTTCC CAAAGGCAGC GTGTGTGGCC 2940 TCGGGCCCTG CGGTGGCATG AAGCATCCCT TCTGGTGTGG GCATCGCTAC GTGTTTTGGG 3000 GGCAGCGTTT CACGGCGGTG CCCTTGCTGT CTCCCTTGGG CTGGCTCGAG CCTGGGGTCC 3060 ATGTCCCTTT GCCGTCCCGT CATGGGGCAG GGAATCCATA GCGGGGCCCA CAGGCAGGGG 3120 TATGAGTGCG TCCCACCCAA CGCAGCACCA GCCCCGGCCA CCGCTCCCCG TGTCCCCAGT 3180 TCCGTCTCAβ CTACCTGGAC TCCAGGACCC TGGAGAAGGG AGACCTGGCA GTGGAGGGAG 3240 GCTGTGCTGT GTGTCCCCCT GCAGGTGTGA CCCCGCCTGC TCTTTCCTCC CCCGCCAGGT 3300 GTGGCCCCGC CTGCTCTTTC CTCCCCCACC AGTATGGCCC CACCTGCTCT TTCCTNCCCC 3360 CCCAAGGTGT GGCCCCACCT GTTCTTTCCT CCCCTGCCGA GGTGTGACCC CACCTGCTCT 3420 TTCCTCCCTC CCAGTATGGC CCCACCTGCT CTTTCCTCCC CCGAGGTGAG GCCCCGCCTG 3480 CTCTTTCCTC CCATGGGAGC CGCTGAGGCG TGCGCACCTG GGCACAGGTT GGGGCTCTGC 3540 AGGATGAGGA AGACAGGCCA ATCCCTTCCC TCCCAGAAGC TGGCCGCCCA GCAGGAGGGA 3600 CTGAGGCCAG ACTCATGTCC AGCAAGGAAC GTGTGGTGTG TCCCCTGGGA AGTCTCTGGG 3660 CCCTGGGAAG AGGGAAGGTG CACGTCCTGG GATGGTTGCG GGGCCCTGTT TTGGGAGACA 3720 AAGGGGTAGA GGGTCTGTCT TGNGCCCCCC CAGACTCTAG CCCGAGCAGT GCAGCCACCT 3780 ACTGCCCCAC CTCAGAGAAG TGCAGCGGGA AGGAGGCTGG AGGTGGTGCG GCGCTGCCTC 3840 GGGTGTCTGC GTGAATGAGC GTGGCCAAGG ACCAGTGCCA CCTCATGGCA AAGAGCTCCC 3900 GCAGTGTTTG TTAGAGTGCA CATCCTACGT GCCCACTGGC ACACACACGT GCTCACATAC 3960 ANGTCNGNGT ACAGGNGTAC ACATGCANGC TTGCACACAT GCACACAGAC CACATAGCAC 4020 ACATGTGCAC TGACCACACC TGTATAGACC ATGCACAGTA CACATACGTG CATACACATG 4080 CCTGCATACA GGCATACACA TGCACGCTTA CATGTACACG TGCACAGATC ACACACATGC 4140 ACACACGTGT AGCTCACACA CAGTATACAC ATACACAAGT GCACAGACCA CACACAGCAC 4200 TAACACATGC ACACACAAAG TGCATAGGCC ACACAGCACA TGCACACAGG TGCACAGACC 4260 ACACAGCACA CACAAGTGCA CAGAGCACAC TGCACACATG CACACACACA CGCGTGCATG 4320 CACACTCCTC GCACTTCCAG CCTTGGAGCC CTTCTGTCTC TGGTCTTTCT CTTTGACCCT 4380 GCTGAGTGTA AGCTGCCTGG GGAGGGGCTA CAAGGAGTAA TTGTGGCTTT AGGGGTCGTG 4440 GTGATGCTGG AATGTCAAGC GCCGTCGTGG GGTATCCGAC TGTCCGGGCT CCTGGTCCGC 4500 AGTGGCAGAG CGCCAGGCAG AGCCAATCAG GGTCTCGTGC TGCCCTTCCC CCCCACAGCC 4560 TGGCAGCCAT CCAGAGGAGG GGCTCTACCA GATGCCAAGG TGCCCCGGTG TCTGTATGGG 4620 TGTCCGGTTG GGTCCTGTGT TTGGTCTGCC CTGGAGGTGG CTGGGCCCTC CTGGGATGGG 4680 TGGCTCAGCC TCGAATCCCA GGCCCCAGCC CAGGCAGGTG CTGCTGCCTG TTβTGGTTTC 4740 CTGGCCCAGC TTCTCCTTCT CCCTCTGCAT AAAATCACAG TCCGTGAGTC TTCCAGCTGC 4800 CACCACGGCT GGGACACGCT GGGGGAGGGC TCCTCCCATG CCTCCTGCAC ACAGCCGTCT 4860 GAGCAGGGCA GGTGCCAACA CCCCCCACCG GAGACAGGCT GCCCCTCAGC GATGCCCCTA 4920 CCTTTTGGGG GGCCTCGTCT CAAGCCCCCC CTTGGAGGCT GAAATCACCC CAGGCACTGT 4980 GAGGGCTTCT CCAGGGGGAC ACCCTTTGAG CTGTGGGTCT GATCACCCCA AGTCCCGCAC 5040 ACGGAGGAGA GGCACAGCCA GGGCGTGTGG TTTAATGTTT GCCCCTTCGG GGCTGGAGGT 5100 CTCAGTGTTT CTAGATTCCA GACCCTGCTG CCAGAGAGAC CTGCTGCCGG AGAGAAGGGG 5160 AGGAGGACTC CAGCTGGGCT CGGTCCCCCA CAGTCAGGGA CCCCCATAAA GGACACCCCC 5220 TTCTCTCTAG AAAGAGCTGG GCTCTCAGCT ATTTCTAGTT GCTTCCCAGA AGCCGAGGAG 5280 CAGAAGGAGC TGTGAGAGCT TTGCAGAAAC GCCCTTGTCC CCGCCCTCCT GAGCTATGAA 5340 TGCCGTACAG AGCAGAGGCT GGGGCATTGG CAAGATCACA GGTTGATGCT GCACAGCCCC 5400 ATTGACACAA ACCCTCAAAG CAGAGGTGAG AGGGACGGTT CACAAAGCTT GGACCTGCCG 5460 TGGAGGGTGC CCGGCAGACG TGGCGTGAGA GGGACGGCTC ACGAGGCTTG GACCTGCTGT 5520 GGAGGGTGCC CAGCAGACGT GGTGTGAGAG GAACGGCTCA CGAGACTTGG ACCTGGTGGA 5580 GGGTGCCCAG CAGACGTGGT GTGAGAGGGA CGGCTCACAG GGCTTGGACC GGAGAGAGAT 5640 GGCTCATGAG ACTTGGACCT GCCGTGGAGG GTGCCCAGCA GACGTGGTAT GAGAGGGATG 5700 GCTCACGAGG CTTGGACCTG GTGGAGGGTG CCCGGCAGAC GTGTGAGAGG GACGGTTCAC 5760 AAGGCTTGGA CCTGCCATGG AGGCTGCCCA GCAGACGTGG TGTGAGAGGG ACAGCTCACG 5820 AGGCTTGGAC CTGCCGTGGA GGGTGCCCAG CAGGGGGCTG AGCTCTGAGG GGTGGGTGCT 5880 CAGTGCACGG GTGCCCCCAG TGTCCTCTGA TCCTGTCCGG TGCCTCCCCC AACCCCCACA 5940 CCCATGCAGA ACTCCCAGGT CACATGCACG TATGTCCAGG GCATGGGGGT GGCGTGAAGA 6000 GGCCTGGTCA GGGCCTTTAG GGGCTGCAGG ACGGAATGGC CACCTGGGGA GCCTGTGTGG 6060 CTGTGCCGGG CAGCCATCCT GCATTCCCAC CCAGCGCGCA GTCTCCACCT CGGCCCCAGC 6120 AAAGCGCTAA GCAGCCGGAG AGACAGCCAG GGCGGCTTCC TGAAGGATGT GGGATGGTGG 6180 ACTCCGGGGT CGAGGGAATA CGCAGGTTCC TGTCCTCCGG GAGACCTAGA GAAGCTGCAC 6240 ACCCAGGAGC TTTCCATGAC CCGGGAGCAT GAGTGAATGG GGGGTTCCAG TTTGCTGAAC 6300 TTTGCTGTCT TGTAAGGGTG GGGGCTGACG GCCGACCCTG GGAGGAGGTG ACACCGCAGG 6360 GGGAGGTTGT GGGCAACGGT GGAGGAGGAG AGACGGGAGG GGACCATTTG GGATGGAGGG 6420 GCCTCTTCAG AGTTTTAAAA GGCGTTTGTG GGGTGGAGTT GAGTGTGCTC TGGGCTTGGA 6480 CACTTGCCGT GGTGCCCCTG GCTGGCCGAG GAGACTGGCT CTGGCCAGGG CCCCGTCCTG 6540 AGAGGTCCTC AGCGTCTGAC TCTCGGCCAG GCGCCAGCAA GGAGGGGCCG GTCCCCGGGG 6600 CTACCAGGCA GGCACGTGCA CATCGCCATC GCCACACGCC AACTCCGCCT GGGTTTTACA 6660 AAGTCGTTGC CTTAATGCAT GTGGACAGGA ACTCCCTGAG GTCGCCCCAT GCCCCCTGGC 6720 TGTGCCAGGT ACGGACGCCC TGGACCCTGC GAACAGGTGG GGCGGGCGAG GGGCCCAAGG 6780 GACGGGCTCC AGAGACACGC GCAGGGCAGG AGGGGTCTCA CGGAGGGGTC TCGCACTGAG 6840 GCGCCCAGAG CTGGTGGTCC CGCTGGACGC CATCCCTCTG CCCGGGATCC ACACGGCCCA 6900 CGTGTGCCCG CCATGCCCGC GCCCCACGCC ATTGCAGTCT TCCATCCTCT GGCGGTGACG 6960 GTGGCTGCAG CTTCCCCATT TGCGCCGTTG CCTCTGGCTG TCTGCACTTT TGTTCATGCT 7020 CCAAAGAACA TTTCATAATG CCTTCAGTAC CGACGTACAC TTCTGACCAT TTTGTATGTG 7080 TCCTTGTGCC GTAGTGACCA GGCCTTTTTT TGGTGGATGT GTTACCCCGC ACACTTCAAT 7140 CTCAACTTTG TGCACCGTCC ATTTTCTAGG GATAGACGCC CAGGGAATGA ACTCTAGTTT 7200 TCTAACAGAT TAGCTGAGAT ATTAACTTAC TCACACGGAC AGGTTGATGC CAGAGCCGTA 7260 AGAATGCGCC AGTGCGGGTT TGCGGGGGAC TTCGGGTGTG GGGTCCTGCG GCCGCGATGG 7320 CCGTGGAAGG TTCTGGGGAT CCCTGCTGCC ACGGGGACGA GTTCGGACGC CAGGTGGACC 7380 TGTGCACTCA GTAAAACGCA GTGATTCAAA AAAAAAAAAA
Seq ID NO: 282 Protein sequence Protein Accession ft: NP_004509.1
11 21 31 41 51
I I I I I
MVQKSRNGGV YPGPSGEKKL KVGFVGLDPG APDSTRDGAL LIAGSEAPKR GSILSKPRAG 60 GAGAGKPPKR NAFYRKLQNF LYNVLERPRG WAFIYHAYVF LLVFSCLVLS VFSTIKEYEK 120 SSEGALYILE IVTIWFGVE YFVRIWAAGC CCRYRGWRGR LKFARKPFCV IDIMVLIASI 180 AVLAAGSQGN VFATSALRSL RFLQILRMIR MDRRGGTWKL LGSWYAHSK ELVTAWYIGF 240 LCLILASFLV YLAEKGENDH FDTYADALWW GLITLTTIGY GDKYPQTWNG RLLAATFTLI 300 GVSFFALPAG ILGSGFALKV QEQHRQKHFE KRRNPAAGLI QSAWRFYATN LSRTDLHSTW 360 QYYERTVTVP MYRLIPPLNQ LELLRNLKSK SGLAFRKDPP PEPSPSQKVS LKDRVFSSPR 420 GVAAKGKGSP QAQTVRRSPS ADQSLEDSPS KVPKSWSFGD RSRARQAFRI KGAASRQNSE 480 EASLPGEDIV DDKSCPCEFV TEDLTPGLKV SIRAVCVMRF LVSKRKFKES LRPYDVMDVI 540 EQYSAGHLDM LSRIKSLQSR VDQIVGRGPA ITDKDRTKGP AEAELPEDPS MMGRLGKVEK 600 QVLSMEKKLD FLVNIYMQRM GIPPTETEAY FGAKEPEPAP PYHSPEDSRE HVDRHGCIVK 660 IVRSSSSTGQ KNFSAPPAAP PVQCPPSTSW QPQSHPRQGH GTSPVGDHGS LVRIPPPPAH 720 ERSLSAYGGG NRASMEFLRQ EDTPGCRPPE GTLRDSDTSI SIPSVDHEEL ERSFSGFSIS 780 QSKENLDALN SCYAAVAPCA KVRPYIAEGE SDTDSDLCTP CGPPPRSATG EGPFGDVGWA 840 GPRK
Seq ID NO: 2838 DNA sequence Nucleic Acid Accession ft: AF152496. Coding sequence: 1..2391
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ATGGAGGCGG GAGGAGAGCG ATTTCTTAGA CAAAGGCAAG TCTTGCTTCT CTTTGTTTTT 60
CTGGGAGGGT CTCTGGCTGG GTCCGAGTCA AGACGCTATT CTGTGGCTGA GGAAAAAGAG 120
AAGGGCTTTT TAATAGCCAA CCTAGCAAAG GATCTGGGAC TAAGGGTAGA GGAACTGGCC 180
GCGAGGGGGG CCCAAGTTGT GTCCAAAGGG AACAAACAGC ATTTTCAGCT CAGTCATCAG 240
ACAGGTGATT TGCTCCTGAA TGAGAAATTG GACCGGGAGG AGCTATGCGG CCCCACAGAA 300
CCATGCATAC TACATTTTCA GATATTACTG CAAAACCCTT TGCAATTCGT TACAAACGAG 360
CTCCGTATCA TAGATGTAAA TGACCATTCT CCGGTATTCT TTGAAAATGA AATGCATCTG 420
AAAATCCTAG AAAGCACTCT GCCAGGAACA GTAATTCCTT TGGGAAATGC TGAGGACTTG 480
GATGTGGGAA GAAACAGCCT CCAAAACTAC ACTATCACTC CGAATTCCCA CTTCCACGTA 540
CTCACTCGCA GTCGTAGGGA CGGAAGGAAG TACCCGGAAC TAGTACTGGA TAAAGCGCTC 600
GATCGGGAGG AGCAGCCGGA ACTCAGCTTA ACGCTCACCG CGCTGGACGG CGGCTCTCCC 660
CCTCGGTCTG GGACAGCCCA GATAAACATC CAGGTCTTAG ATATAAACGA CAATGCACCA 720
GAATTTGCAC AGCCGCTCTA TGAGGTTGCA GTTCTAGAGA ATACCCCCGT TAACTCTGTC 780
ATTGTCACTG TCTCGGCTTC TGACTTAGAT ACAGGAAGTT TTGGGACAAT ATCATΛTGCA 840
TTTTTTCATG CTTCTGAAGA AATTCGCAAA ACTTTTCAGC TAAATCCAAT TACTGGTGAT 900
ATGCAACTGG TCAAATATTT GAATTTTGAA GCGATTAATA GTTATGAAGT CGACATCGAG 960
GCCAAGGATG GCGGAGGCCT ATCCGGAAAG TCTACAGTCA TAGTCCAGGT GGTTGATGTC 1020
AACGACAACC CACCGGAACT GACCTTGTCT TCAGTAAACA GCCCTATTCC TGAGAACTCG 1080
GGAGAGACTG TACTGGCTGT TTTCAGTGTT TCTGATCTAG ACTCTGGAGA CAACGGAAGA 1140
GTGATGTGTT CCATTGAGAA CAATCTCCCC TTCTTCCTGA AACCATCTGT AGAGAATTTT 1200
TACACCCTAG TGTCAGAAGG CGCGCTGGAC AGAGAGACCA GATCCGAGTA CAACATTACC 1260
ATCACTATCA CTGACCTGGG GACACCCAGG CTGAAAACCA AGTACAACAT AACCGTGCTG 1320
GTCTCCGACG TCAATGACAA CGCCCCCGCC TTGACCCAAA TCTCCTACAC CCTGTTCGTC 1380
CGCGAGAACA ACAGCCCCGC CCTGCACATC GGCAGTGTCA GCGCCACAGA CAGAGACTCA 1440
GGCACCAACG CCCAGGTAAC CTACTCGCTG CTGCCGCCCC AGGACCCGCA CCTGCCCCTC 1500
TCTTCCCTGG TCTCCATCAA CGCGGACAAC GGCCACCTGT TTGCCCTCAG GTCGCTGGAC 1560
TACGAGGCCC TGCAGGCGTT CGAGTTCCGC GTGGGGGCCA CAGACCGTGG CTCCCCGGCT 1620
TTGAGCAGCG AGGCGCTGGT GCGCGTGCTG GTGCTGGACG CCAACGACAA CTCGCCCTTC 1680
GTGCTGTACC CGCTGCAGAA CGGCTCCGCG CCCTGCACCG AGCTGGTGCC CCGGGCGGCT 1740
GAGCCGGGCT ACCTGGTGAC CAAGGTGGTG GCGGTGGACG GCGACTCGGG CCAGAACGCC 1800
TGGCTGTCGT ACCAGCTGCT CAAGGCCACG GAGCCCGGGC TGTTCGGCGT GTGGGCGCAC 1860
AATGGCGAAG TGCGCACCGC CAGGCTGCTG AGCGAGCGCG ACGCGGCCAA GCACAGGCTG 1920
GTGGTGCTGG TCAAGGACAA TGGCGAGCCT CCGCGCTCGG CCACCGCCAC GCTGCATGTG 1980
CTCCTGGTGG ACGGCTTCTC CCAGCCCTAC CTGCCTCTCC CGGAGGCGGC ACCGGCCCAG 2040
GCCCAGGCCG ACTTGCTCAC CGTCTACCTG GTGGTGGCAT TGGCCTCGGT GTCTTCGCTC 2100
TTCCTCTTTT CGCTGCTCCT GTTCGTGGCG GTGCGGCTGT GCAGGAGGAG CAGGGCGGCC 2160
TCGGTGGGTC GCTGCTCGGT GCCCGAGGGC CCCTTTCCAG GGCAGATGGT GGACGTGAGC 2220
GGCACCGGGA CCCTGTCCCA GAGCTACCAG TACGAGGTGT GTCTGACTGG AGGCTCCGGG 2280
ACAAATGAGT TCAAGTTCCT GAAGCCAATT ATCCCCAACT TCGTTGCTCA GGGTGCAGAG 2340
AGGGTTAGCG AGGCAAATCC CAGTTTCAGG AAGAGCTTTG AATTCAGTTA A
Seq ID NO: 284 Protein sequence Protein Accession #: AAD43757.1
1 11 21 31 41 51
I I I I I I
MEAGGERFLR QRQVLLLFVF LGGSLAGSES RRYSVAEEKE KGFLIANLAK DLGLRVEELA 60 ARGAQWSKG NKQHFQLSHQ TGDLLLNEKL DREELCGPTE PCILHFQILL QNPLQFVTNE 120 LRIIDVNDHS PVFFENEMHL KILESTLPGT VIPLGNAEDL DVGRNSLQNY TITPNSHFHV 180 LTRSRRDGRK YPELVLDKAL DREEQPELSL TLTALDGGSP PRSGTAQINI QVLDINDNAP 240 EFAQPLYEVA VLENTPVNSV IVTVSASDLD TGSFGTISYA FFHASEEIRK TFQLNPITGD 300 MQLVKYLNFE AINSYEVDIE AKDGGGLSGK STVIVQWDV NDNPPELTLS SVNSPIPENS 360 GETVLAVFSV SDLDSGDNGR VMCSIENNLP FFLKPSVENF YTLVSEGALD RETRSEYNIT 420 ITITDLGTPR LKTKYNITVL VΞDVNDNAPA FTQISYTLFV RENNSPALHI GSVSATDRDS 480 GTNAQVTYSL LPPQDPHLPL SSLVSINADN GHLFALRSLD YEALQAFEFR VGATDRGSPA 540 LSSEALVRVL VLDANDNSPF VLYPLQNGSA PCTELVPRAA EPGYLVTKW AVDGDSGQNA 600 WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKHRL WLVKDNGEP PRSATATLHV 660 LLVDGFSQPY LPLPEAAPAQ AQADLLTVYL WALASVSSL FLFSVLLFVA VRLCRRSRAA 720 SVGRCSVPEG PFPGQMVDVS GTGTLSQSYQ YEVCLTGGSG TNEFKFLKPI IPNFVAQGAE 780 RVSEANPSFR KSFEFS
Seq ID NO: 285 DNA sequence
Nucleic Acid Accession #: NM.001794.2
Coding sequence: 15..2765
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| 1 | 1 | 1
CGCCGGCGGG GAAGATGACC GCGGGCGCCG GCGTGCTCCT TCTGCTGCTC TCGCTCTCCG 60
GCGCGCTCCG GGCCCATAAT GAGGATCTTA CAACTAGAGA GACCTGCAAG GCTGGGTTCT 120
CTGAAGATGA TTACACGGCA TTAATCTCCC AAAATATTCT AGAAGGGGAA AAGCTACTTC 180
AAGTCAAGTT CAGCAGCTGT GTGGGGACCA AGGGGACACA ATATGAGACC AACAGCATGG 240
ACTTCAAAGT TGGGGCAGAT GGGACAGTCT TCGCCACCCG GGAGCTGCAG GTCCCCTCCG 300
AGCAGGTGGC GTTCACGGTG ACTGCATGGG ACAGCCAGAC AGCAGAGAAA TGGGACGCCG 360
TGGTGCGGTT GCTGGTGGCC CAGACCTCGT CCCCGCACTC TGGACACAAG CCGCAGAAAG 420
GAAAGAAGβT CGTGGCTCTG GACCCCTCTC CGCCTCCGAA GGACACCCTG CTGCCGTGGC 480
CCCAGCACCA GAACGCCAAC GGGCTGAGGC GGCGCAAACG GGACTGGGTC ATCCCGCCCA 540
TCAACGTGCC CGAGAACTCG CGCGGGCCCT TCCCGCAGCA GCTCGTGAGG ATCCGGTCCG 600
ACAAAGACAA TGACATCCCC ATCCGGTACA GCATCACGGG AGTGGGCGCC GACCAGCCCC 660
CCATGGAGGT CTTCAGCATT GACTCCATGT CCGGCCGGAT GTACGTCACA AGGCCCATGG 720
ACCGGGAGGA GCACGCCTCT TACCACCTCC GAGCCCACGC TGTGGACATG AATGGCAACA 780
AGGTGGAGAA CCCCATCGAC CTGTACATCT ACGTCATCGA CATGAATGAC AACCGCCCTG 840
AGTTCATCAA CCAGGTCTAC AACGGCTCCG TGGAGGAGGG CTCCAAGCCA GGCACCTACG 900
TGATGACCGT CACGGCCAAC GATGCTGACG ACAGCACCAC GGCCAACGGG ATGGTGCGGT 960
ACCGGATCGT GACCCAGACC CCACAGAGCC CGTCCCAGAA TATGTTCACC ATCAACAGCG 1020
AGACTGGAGA TATCGTCACA GTGGCGGCTG GCCTGGACCG AGAGAAAGTT CAGCAGTACA 1080
CAGTCATCGT TCAGGCCACA GATATGGAAG GAAATCTCAA CTATGGCCTC TCAAACACAG 1140
CCACAGCCAT CATCACGGTG ACAGATGTGA ATGACAACCC GCCAGAATTT ACCGCCAGCA 1200
CGTTTGCAGG GGAGGTCCCC GAAAACCGCG TGGAGACCGT GGTCGCAAAC CTCACGGTGA 1260
TGGACCGAGA TCAGCCCCAC TCTCCAAACT GGAATGCCGT TTACCGCATC ATCAGTGGGG 1320
ATCCATCCGG GCACTTCAGC GTCCGCACAG ACCCCGTAAC CAACGAGGGC ATGGTCACCG 1380
TGGTGAAGGC AGTCGACTAC GAGCTCAACA GAGCTTTCAT GCTGACAGTG ATGGTGTCCA 1440
ACCAGGCGCC CCTGGCCAGC GGAATCCAGA TGTCCTTCCA GTCCACGGCA GGGGTGACCA 1500
TCTCCATCAT GGACATCAAC GAGGCTCCCT ACTTCCCCTC AAACCACAAG CTGATCCGCC 1560
TGGAGGAGGG CGTGCCCCCC GGCACCGTGC TGACCACGTT TTCAGCTGTG GACCCTGACC 1620
GGTTCATGCA GCAGGCTGTG AGATACTCAA AGCTGTCAGA CCCAGCGAGC TGGCTGCACA 1680
TCAATGCCAC CAACGGCCAG ATCACCACGG CGGCAGTGCT GGACCGTGAG TCCCTCTACA 1740
CCAAAAACAA CGTCTACGAG GCCACCTTCC TGGCAGCTGA CAATGGGATA CCCCCGGCCA 1800
GCGGCACCGG GACCCTCCAG ATCTATCTCA TTGACATCAA CGACAACGCC CCTGAGCTGC 1860
TGCCCAAGGA GGCGCAGATC TGCGAGAAGC CCAACCTGAA CGCCATCAAC ATCACGGCGG 1920
CCGACGCTGA CGTCGACCCC AACATCGGCC CCTACGTCTT CGAGCTGCCC TTTGTCCCGG 1980
CGGCCGTGCG GAAGAACTGG ACCATCACCC GCCTGAACGG TGACTATGCC CAACTCAGCT 2040
TGCGCATCCT GTACCTGGAG GCCGGGATGT ATGACGTCCC CATCATCGTC ACAGACTCTG 2100
GAAACCCTCC CCTGTCCAAC ACCTCCATCA TCAAAGTCAA GGTGTGCCCA TGTGATGACA 2160
ACGGGGACTG CACCACCATT GGCGCAGTGG CAGCGGCTGG TCTGGGCACC GGTGCCATCG 2220
TGGCCATCCT CATCTGCATC CTCATCCTGC TGACCATGGT CCTGCTGTTT GTCATGTGGA 2280
TGAAGCGGCG AGAGAAGGAG CGCCACACGA AGCAGCTGCT CATTGACCCC GAGGACGACG 2340
TCCGCGACAA CATCCTCAAG TATGACGAGG AAGGCGGTGG CGAGGAGGAC CAGGACTACG 2400
ACCTCAGCCA GCTGCAGCAG CCGGAAGCCA . TGGGGCACGT GCCAAGCAAA GCCCCTGGCβ 2460
TGCGTCGCGT GGATGAGCGG CCGGTGGGCG CTGAGCCCCA GTACCCGATC AGGCCCATGG 2520
TGCCGCACCC AGGCGACATC GGTGACTTCA . TCAATGAGGG ACTCCGCGCT GCTGACAACβ 2580
ACCCCACGGC ACCCCCCTAT GACTCCCTGC ! TGGTCTTCGA CTACGAGGGG AGCGGCTCCA 2640
CCGCAGGCTC CGTCAGCTCC CTGAACTCAT 1 CCAGTTCCGG GGACCAAGAC TACGATTACC 2700
TCAACGACTG GGGGCCCAGA TTCAAGAAGC 1 TGGCGGACAT GTATGGAGGT GGTGAAGAGG 2760
ATTGACTGAC CTCGCATCTT CGGACCGAAG ' TGAGAGCCGT GCTCGGACGC CGGAGGAGCA 2820
GGACTGAGCA GAGGCGGCCG GTCTTCCCGA . CTCCCTGCGG CTGTGTCCTT AGTGCTGTTA 2880
GGAGGCCCCC CAATCCCCAC GTTGAGCTGT ' CTAGCATGAG CACCCACCCC CACAGCGCCC 2940
TGCACCCGGC CGCTGCCCAG CACCGCGCTG 1 GCTGGCACTG AAGGACAGCA AGAGGCACTC 3000
TGTCTTCACT TGAATTTCCT AGAACAGAAG 1 CACTGTTTTT AAAAAAAAAA AAAAAAAAAG 3060
AAG
Seq ID NO: 286 Protein sequence Protein Accession it: NP 001785.2
11 21 31 41 51
I I I I I
MTAGAGVLLL LLSLSGALRA HNEDLTTRET CKAGFSEDDY TALISQNILE GEKLLQVKFS 60 SCVGTKGTQY ETNSMDFKVG ADGTVFATRE LQVPSEQVAF TVTAWDSQTA EKWDA RLL 120 VAQTSSPHSG HKPQKGKKW ALDPSPPPKD TLLPWPQHQN ANGLRRRKRD WVIPPINVPE 180 NSRGPFPQQL VRIRSDKDND IPIRYSITGV GADQPPMEVF SIDSMSGRMY VTRPMDREEH 240 ASYHLRAHAV DMNGNKVENP IDLYIYVIDM NDNRPEFINQ VYNGSVDEGS KPGTYVMTVT 300 ANDADDSTTA NGMVRYRIVT QTPQSPSQNM FTINSETGDI VTVAAGLDRE KVQQYTVIVQ 360 ATDMEGNLNY GLSNTATAII TVTDVNDNPP EFTASTFAGE VPENRVETW ANLTVMDRDQ 420 PHSPNWNAVY RIISGDPSGH FSVRTDPVTN EGMVTWKAV DYELNRAFML TVMVSNQAPL 480 ASGIQMSFQS TAGVTISIMD INEAPYFPSN HKLIRLEEGV PPGTVLTTFS AVDPDRFMQQ 540 AVRYSKLSDP ASWLHINATN GQITTAAVLD RESLYTKNNV YEATFLAADN GIPPASGTGT 600 LQIYLIDIND NAPELLPKEA QICEKPNLNA INITAADADV DPNIGPYVFE LPFVPAAVRK 660 NWTITRLNGD YAQLSLRILY LEAGMYDVPI IVTDSGNPPL SNTSIIKVKV CPCDDNGDCT 720 TIGAVAAAGL GTGAIVAILI CILILLTMVL LFVMWMKRRE KERHTKQLLI DPEDDVRDNI 780 LKYDEEGGGE EDQDYDLSQL QQPEAMGHVP SKAPGVRRVD ERPVGAEPQY PIRPMVPHPG 840 DIGDFINEGL RAADNDPTAP PYDSLLVFDY EGSGSTAGSV SSLNSSSSGD QDYDYLNDWG 900 PRFKKLADMY GGGEED
Seq ID NO: 287 DNA sequence
Nucleic Acid Accesεion #: AF152495.1
Coding sequence: 1..2397
11 21 31 41 51
I I I I I
ATGGAGGCCG GAGAGGGGAA GGAGCGCGTT CCGAAACAAA GGCAAGTCCT GATATTCTTT 60
GTTTTGCTGG GCATAGCTCA GGCTAGTTGC CAGCCTAGGC ACTATTCAGT GGCCGAGGAA 120
ACGGAGAGTG GCTCCTTTGT GGCCAATTTG TTAAAAGACC TGGGGCTGGA GATAGGAGAA 180
CTTGCTGTGA GGGGGGCCAG GGTCGTTTCC AAAGGAAAAA AAATGCATTT GCAGTTCGAT 240
AGGCAGACCG GGGATTTGTT GTTAAATGAG AAATTGGACC GGGAGGAGCT GTGCGGCCCC 300
ACAGAGCCCT GTGTCCTACC TTTCCAGGTG TTACTAGAAA ATCCCTTGCA GTTTTTTCAG 360
GCGGAGCTAC GGATTAGGGA CGTAAATGAT CATTCCCCAG TTTTCCTAGA CAAAGAAATA 420
CTTTTGAAAA TTCCAGAAAG TATCACTCCT GGAACTACTT TCTTAATAGA ACGTGCCCAG 480
GACTTGGATG TAGGAACCAA CAGTCTCCAA AATTACACAA TCAGTCCCAA TTTCCACTTT 540
CATCTTAATT TACAAGACAG TCTCGATGGC ATAATATTAC CACAGCTGGT GCTGAACAGA 600
GCCCTGGATC GCGAGGAGCA GCCTGAGATC AGGTTAACCC TCACAGCGCT AGATGGCGGG 660
AGTCCACCCA GGTCCGGCAC GGCCCTGGTA CGGATTGAAG TTGTGGACAT CAATGACAAC 720
GTCCCAGAGT TTGCAAAGCT GCTCTATGAG GTGCAGATCC CGGAGGACAG CCCCGTTGGA 780
TCCCAGGTTG CCATCGTCTC TGCCAGGGAT TTAGACATTG GAACTAATGG AGAAATATCT 840
TATGCATTTT CCCAAGCATC TGAAGACATT CGCAAAACGT TTCGATTAAG TGCAAAATCG 900
GGAGAACTGC TTTTAAGACA GAAACTGGAT TTCGAATCCA TCCAGACATA CACAGTAAAT 960
ATTCAGGCGA CAGATβGTGG GGGCCTATCT GGAACTTGTG TGGTATTTGT CCAAGTGATG 1020
GATTTGAATG ACAATCCTCC GGAACTAACT ATGTCGACAC TTATCAATCA GATCCCAGAA 1080
AACTTGCAGG ACACCCTCAT TGCTGTATTC AGCGTTTCAG ATCCTGACTC CGGAGACAAC 1140
GGAAGGATGG TGTGCTCCAT CCAAGATGAT CTTCCTTTTT TCTTGAAACC TTCTGTTGAG 1200
AACTTTTACA CTCTGGTGAT AAGCACGGCC CTGGACCGGG AGACCAGATC CGAATACAAC 1260
ATCACCATCA CCGTCACCGA CTTCGGGACA CCCAGGCTGA AAACCGAGCA CAACATAACC 1320
GTGCTGGTCT CCGACGTCAA TGACAACGCC CCCGCCTTCA CCCAAACCTC CTACACCCTG 1380
TTCGTCCGCG AGAACAACAG CCCCGCCCTG CACATCGGCA GCGTCAGCGC CACAGACAGA 1440
GACTCGGGCA CCAACGCCCA GGTCACCTAC TCGCTGCTGC CGCCCCAGGA CCCGCACCTG 1500
CCCCTCGCCT CCCTGGTCTC CATCAACGCG GACAACGGCC ACCTGTTCGC TCTCCAGTCG 1560
CTGGACTACG AGGCCCTGCA GGCGTTCGAG TTCCGCGTGG GCGCCGCAGA CCGCGGCTCC 1620
CCGGCGTTGA GCAGCGAGGC GCTGGTGCGC GTGCTGGTGC TGGACGCCAA CGACAACTCG 1680
CCCTTCGTGC TGTACCCGCT GCAGAACGGC TCCGCGCCCT GCACCGAGCT GGTGCCCCGG 1740
GCGGCCGAGC CGGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGGCGA CTCGGGCCAG 1800
AACGCCTGGC TGTCGTACCA GCTGCTCAAG GCCACGGAGC CCGGGCTGTT CGGCGTGTGG 1860
GCGCACAATG GCGAGGTGCG CACCGCCAGG CTGCTGAGGG AGCGCGACGC TGCCAAGCAG 1920
AGGCTGGTGG TGCTGGTCAA GGACAATGGC GAGCCTCCGC GCTCGGCCAC CGCCACGCTG 1980
CACGTGCTCC TGGTGGACGG CTTCTCCCAG CCCTACCTGC TGCTCCCGGA GGCGGCACCG 2040
GCCCAGGCCC AGGCCGACTT GCTCACCGTC TACCTGGTGG TGGCGTTGGC CTCGGTGTCT 2100
TCGCTCTTCC TCTTCTCGGT GCTCCTGTTC GTGGCGGTGC GGCTGTGCAG GAGGAGCAGG 2160
GCGGCCTCGG TGGGTCGCTG CTCGGTGCCC GAGGGCCCCT TTCCAGGGCA GATGGTGGAC 2220
GTGAGCGGCA CCGGGACCCT GTCCCAGAGC TACCAGTACG AGGTGTCTCT GACTGGAGGC 2280
TCCGGGACAA ATGAGTTCAA GTTCCTGAAG CCAATTATCC CCAACTTCGT TGCTCAGGGT 2340
GCAGAGAGGG TTAGCGAGGC AAATCCCAGT TTCAGGAAGA GCTTTGAATT CACTTAA
Seq ID NO: 288 Protein sequence Protein Accession #: AAD43756.1
11 21 31 41 51
I I I I I
MEAGEGKERV PKQRQVLIFF VLLGIAQASC QPRHYSVAEE TESGSFVANL LKDLGLEIGE 60 LAVRGARWS KGKKMHLQFD RQTGDLLLNE KLDREELCGP TEPCVLPFQV LLENPLQFFQ 120 AELRIRDVND HSPVPLDKEI LLKIPESITP GTTFLIERAQ DLDVGTNSLQ NYTISPNFHF 180 HLNLQDSLDG IILPQLVLNR ALDREEQPEI RLTLTALDGG SPPRSGTALV RIEWDINDN 240 VPEFAKLLYE VQIPEDSPVG SQVAIVSARD LDIGTNGEIS YAFSQASEDI RKTFRLSAKS 300 GELLLRQKLD FESIQTYTVN IQATDGGGLS GTCWFVQVM DLNDNPPELT MSTLINQIPE 360 NLQDTLIAVF SVSDPDSGDN GRMVCSIQDD LPFFLKPSVE NFYTLVISTA LDRETRSEYN 420 ITITVTDFGT PRLKTEHNIT VLVSDVNDNA PAFTQTSYTL FVRENNSPAL HIGSVSATDR 480 DSGTNAQVTY SLLPPQDPHL PLASLVSINA DNGHLFALQS LDYEALQAFE FRVGAADRGS 540 PALSSEALVR VLVLDANDNS PFVLYPLQNG SAPCTELVPR AAEPGYLVTK WAVDGDSGQ 600 NAWLSYQLLK ATEPGLFGVW AHNGEVRTAR LLRERDAAKQ RLWLVKDNG EPPRSATATL 660 HVLLVDGFSQ PYLLLPEAAP AQAQADLLTV YLWALASVS SLFLFSVLLF VAVRLCRRSR 720 AASVGRCSVP EGPFPGQMVD VSGTGTLSQS YQYEVCLTGG SGTNEFKFLK PIIPNFVAQG 780 AERVSEANPS FRKSFEFT
Seq ID NO: 289 DNA sequence
Nucleic Acid Accession #: NM_018674.1
Coding sequence: 390..2009
21 31 51 I I CGGAGCACAT GCTGAGCGGA GCGGCTGGGG CTGCGCGGCG TGGCGGAGCA GCGCTCGCTC 60
CCTCGCTCAC TCGCTCGCTC GCAGGGACAC ACGCAGGGGC TGACAGCTGT GCTGGTGCTG 120
ATAAGGGAAβ CCACAAGGAG ACGATCGAGG AGAGAGACAA GCGGCAGCAG AGGCAGCAGC 180
GGCAGAGGCA GCACCAGGGC TGCGGAGCTG CTGGGAGTGG GAGTGACTCC CCCACCTCGG 240
GCCCCCACCC TGTCCCTGTC CTCTTCCCGC TTGCCCTGAG TTTAGAAGAG CAGCCGCTGC 300
CACCACTGCC ACTCGGGAGG GCACCAGGGC TGCTGGCTAG GGAGGGACAG GGCAGGGAGG 360
CTCTGGCCAG TCCCAGCAGC CGGGGACAGA TGCCGATCGA GATTGTGTGC AAAATCAAAT 420
TTGCTGAGGA GGATGCGAAA CCCAAGGAGA AGGAGGGAGG GGATGAGCAG AGCCTCCTCG 480
GGGCTGTTGC CCCTGGAGCA GCCCCCCGAG ACCTGGCCAC CTTTGCCAGC ACCAGCACCC 540
TGCATGGACT GGGCCGGGCC TGTGGCCCAG GCCCCCACGG ACTGCGCAGA ACCCTGTGGG 600
CACTGGCCCT ACTCACCTCG CTGGCTGCCT TCCTGTACCA GGCGGCTGGC CTGGCCCGGG 660
GCTACCTGAC CCGGCCTCAC CTGGTGGCAA TGGACCCCGC TGCCCCAGCC CCAGTGGCGG 720
GCTTCCCGGC TGTCACCCTC TGCAATATCA ACCGCTTCCG GCATTCGGCA CTCAGCGATG 780
CCGACATCTT CCACCTGGCC AATCTGACAG GGCTGCCCCC CAAAGACCGG GATGGGCACC 840
GTGCGGCTGG CCTGCGCTAC CCAGAGCCTG ACATGGTAGA CATCCTCAAC CGCACTGGCC 900
ACCAGCTCGC CGACATGCTT AAGAGCTGCA ACTTCAGTGG GCATCACTGC TCCGCCAGCA 960
ACTTCTCTGT GGTCTATACT CGCTATGGGA AGTGTTACAC CTTCAACGCG GACCCGCGGA 1020
GCTCGCTGCC CAGCCGGGCA GGGGGCATGG GCAGTGGCCT GGAGATCATG CTGGACATCC 1080
AGCAGGAGGA GTACCTGCCC ATCTGGAGGG AGACAAATGA GACGTCGTTT GAGGCAGGTA 1140
TTCGGGTGCA GATCCACAGC CAGGAGGAGC CGCCCTACAT CCACCAGCTG GGGTTCGGGG 1200
TGTCCCCAGG CTTCCAGACC TTTGTGTCCT GCCAGGAACA GCGGCTGACC TACCTGCCCC 1260
AGCCCTGGGG CAACTGCCGC GCAGAGAGTG AGCTCAGGGA GCCTGAGCTT CAGGGCTACT 1320
CGGCCTACAG TGTGTCTGCC TGCCGGCTGC GCTGTGAAAA GGAGGCCGTG CTTCAGCGCT 1380
GCCACTGCCG GATGGTGCAC ATGCCAGGCA ATGAGACCAT CTGCCCACCA AATATCTACA 1440
TCGAGTGTGC AGACCACACA CTGGACTCCC TGGGTGGGGG CCCTGAGGGC CCGTGCTTCT 1500
GCCCCACCCC CTGCAACCTG ACACGCTATG GGAAAGAGAT CTCCATGGTC AGGATCCCCA 1560
ACAGGGGCTC AGCCCGGTAC CTGGCGAGGA AGTACAACCG CAACGAGACC TACATACGGG 1620
AGAACTTCCT GGTCCTAGAT GTCTTCTTTG AGGCCCTGAC CTCTGAAGCC ATGGAGCAGC 1680
GAGCAGCCTA TGGCCTGTCA GCCCTGCTGG GAGACCTCGG GGGACAGATG GGCCTGTTCA 1740
TTGGGGCCAG CATCCTCACG TTGCTGGAGA TCCTCGACTA CATCTATGAG GTGTCCTGGG 1800
ATCGACTGAA GCGGGTATGG AGGCGTCCCA AGACCCCCCT GCGGACCTCC ACTGGGGGCA 1860
TCTCCACTTT GGGGCTTCAG GAGCTGAAGG AACAGAGTCC CTGCCCGAGC CTGGGCCGAG 1920
CGGAGGGTGG GGGGGTCAGC AGTCTGCTCC CCAATCACCA CCACCCCCAC GGTCCCCCAG 1980
GAGGTCTCTT TGAAGATTTT GCTTGCTAGG ACGGTGCTGT GACTGAAAGG ACCCAGGAGT 2040
CTGGGACCCC TCCTGGGATC CCCAGCACAT TCTCCTGCTC CTGGGAGAGG CCTGGGGGCG 2100
GTGCTCACTG GGAGGGCCAG GACTCAGTTC CTGCTCTCAT CCTCCCCTGC CCTGATGTCA 2160
GCTGCTTTGC ACAAAGGTCC TTCTTGTCCA CACCCCTTAT CCCCAGGCTG GTGCCCCGGG 2220
AGGGCTGGAG ACCAGGCCAT GGGCCCTCAC GGAGAGGAAG GGAAGGAAGG AGAGGGAGGG 2280
GGAGGATAGA GCCCATCCCA GCCGGGGAGG GGGAGCCCTC TGTACATTTG TAAATATTTA 2340
GGGAAAGCCG GGTGGGGGGA GGGGATACAG ATGTAGAAGG TGGGTAGGGC TACAGGGGTG 2400
GGTGATTTAG GGACAGCCAG GGTCCCAGCC CCAATGTCAG CAGGATAGGG AGAGCCCCAG 2460
GACTCAGGAG TGCTGGGCTG GTCCTACTTC CTGCCCCTCT CCAGGCCCAG CTCCCCTCTT 2520
GGCAGGGGGA GAGGATGGCC CAGCAGGCCT GGCCCAGCTC CCAGTTCCCC CTGCACCAGC 2580
CCCACCCCTA GAGTCCCTTC TATAGGGAGG GGGCAGGAGA CCTTCCAGAC TTCGGCTGAG 2640
CTTGGAGGGT GGGAAGGGAG CCTTCTCAGT CCTCTCTCCC TCCAGTCTGA TTTTATAAAG 2700 TGCTGACGAG
Seq ID NO: 290 Protein sequence Protein Accession #: NP_061144.1
1 11 21 31 41 51
I I I I I I
MPIEIVCKIK FAEEDAKPKE KEAGDEQSLL GAVAPGAAPR DLATFASTST LHGLGRACGP 60
GPHGLRRTLW ALALLTSLAA FLYQAAGLAR GYLTRPHLVA MDPAAPAPVA GFPAVTLCNI 120
NRFRHSALSD ADIFHLANLT GLPPKDRDGH RAAGLRYPEP DMVDILNRTG HQLADMLKSC 180
NFSGHHCSAS NFS YTRYG KCYTFNADPR SSLPSRAGGM GSGLEIMLDI QQEEYLPIWR 240
ETNETSFEAG IRVQIHSQEE PPYIHQLGFG VSPGFQTFVS CQEQRLTYLP QPWGNCRAES 300
ELREPELQGY SAYSVSACRL RCEKEAVLQR CHCRMVHMPG NETICPPNIY IECADHTLDS 360
LGGGPEGPCF CPTPCNLTRY GKEISMVRIP NRGSARYLAR KYNRNETYIR ENFLVLDVFF 420
EALTSEAMEQ RAAYGLSALL GDLGGQMGLF IGASILTLLE ILDYIYEVSW DRLKRVWRRP 480 KTPLRTSTGG ISTLGLQELK EQSPCPSLGR AEGGGVSSLL PNHHHPHGPP GGLFEDFAC
Seq ID NO: 291 DNA sequence Nucleic Acid Accession ft: Eos sequence Coding sequence: 62..895
1 11 21 31 41 51
I I I I I I
CACTGCTCTG AGAATTTGTG AGCAGCCCCT AACAGGCTGT TACTTCACTA CAACTGACGA 60
TATGATCATC TTAATTTACT TATTTCTCTT GCTATGGGAA GACACTCAAG GATGGGGATT 120
CAAGGATGGA ATTTTTCATA ACTCCATATG GCTTGAACGA GCAGCCGGTG TGTACCACAG 180
AGAAGCACGG TCTGGCAAAT ACAAGCTCAC CTACGCAGAA GCTAAGGCGG TGTGTGAATT 240
TGAAGGCGGC CATCTCGCAA CTTACAAGCA GCTAGAGGCA GCCAGAAAAA TTGGATTTCA 300
TGTCTGTGCT GCTGGATGGA TGGCTAAGGG CAGAGTTGGA TACCCCATTG TGAAGCCAGG 360
GCCCAACTGT GGATTTGGAA AAACTGGCAT TATTGATTAT GGAATCCGTC TCAATAGGAG 420
TGAAAGATGG GATGCCTATT GCTACAACCC ACACGCAAAG GAGTGTGGTG GCGTCTTTAC 480
AGATCCAAAG CAAATTTTTA AATCTCCAGG CTTCCCAAAT GAGTACGAAG ATAACCAAAT 540
CTGCTACTGG CACATTAGAC TCAAGTATGG TCAGCGTATT CACCTGAGTT TTTTAGATTT 600
TGACCTTGAA GATGACCCAG GTTGCTTGGC TGATTATGTT GAAATATATG ACAGTTACGA 660
TGATGTCCAT GGCTTTGTGG GAAGATACTG TGGAGATGAG CTTCCAGATG ACATCATCAG 720
TACAGGAAAT GTCATGACCT TGAAGTTTCT AAGTGATGCT TCAGTGACAG CTGGAGGTTT 780
CCAAATCAAA TATGTTGCAA TGGATCCTGT ATCCAAATCC AGTCAAGGAA AAAATACAAG 840
TACTACTTCT ACTGGAAATA AAAACTTTTT AGCTGGAAGA TTTAGCCACT TATAAAAAAA 900
AAAAAAAGGA TGATCAAAAC ACACAGTGTT TATGTTGGAA TCTTTTGGAA CTCCTTTGAT 960 CTCACTCTTA TTATTAACAT TTATTTATTA TTTTTCTAAA TGTGAAAGCA ATACATAATT 1020
TAGGGAAAAT TGGAAAATAT AGGAAACTTT AAACGAGAAA ATGAAACCTC TCATAATCCC 1080
ACTGCATAGA AATAACAAGC GTTAACATTT TCATATTTTT TTCTTTCAGT GATTTTTCTA 1140
TTTGTGGTAT ATGTATATAT GTACCTATAT GTATTTGCAT TTGAAATTTT GGAATCCTGC 1200
TCTATGTACA GTTTTGTATT ATACTTTTTA AATCTTGAAC TTTATAAACA TTTTCTGAAA 1260
TCATTGATTA TTCTACAAAA ACATGATTTT AAACAβCTGT AAAATATTCT ATGATATGAA 1320
TGTTTTATGC ATTATTTAAG CCTGTCTCTA TTGTTGGAAT TTCAGGTCAT TTTCATAAAT 1380 ATTCTTGCAA TAAATATCCT TGAACACACA AAAAAAAAAA AA Seq ID NO : 292 Protein sequence
Protein Accesεion ft : Eoε sequence
1 11 21 31 41 51
I I I I I I
MIILIYLFLL LWEDTQGWGF KDGIFHNSIW LERAAGVYHR EARSGKYKLT YAEAKAVCEF 60
EGGHLATYKQ LEAARKIGFH VCAAGWMAKG RVGYPIVKPG PNCGFGKTGI IDYGIRLNRS 120
ERWDAYCYNP HAKECGGVFT DPKQIFKSPG FPNEYEDNQI CYWHIRLKYG QRIHLSFLDF 180
DLEDDPGCLA DYVEIYDSYD DVHGFVGRYC GDELPDDI IS TGNVMTLKFL SDASVTAGGF 240 QIKYVAMDPV SKSSQGKNTS TTSTGNKNFL AGRFSHL
Seq ID NO : 293 DNA sequence
Nucleic Acid Accession ft : NM_007115 . 1
Coding sequence : 69 . . 902
1 11 21 31 41 51
I I I I I I
GAATTCGCAC TGCTCTGAGA ATTTGTGAGC AGCCCCTAAC AGGCTGTTAC TTCACTACAA 60
CTGACGATAT GATCATCTTA ATTTACTTAT TTCTCTTGCT ATGGGAAGAC ACTCAAGGAT 120
GGGGATTCAA GGATGGAATT TTTCATAACT CCATATGGCT TGAACGAGCA GCCGGTGTGT 180
ACCACAGAGA AGCACGGTCT GGCAAATACA AGCTCACCTA CGCAGAAGCT AAGGCGGTGT 240
GTGAATTTGA AGGCGGCCAT CTCGCAACTT ACAAGCAGCT AGAGGCAGCC AGAAAAATTG 300
GATTTCATGT CTGTGCTGCT GGATGGATGG CTAAGGGCAG AGTTGGATAC CCCATTGTGA 360
AGCCAGGGCC CAACTGATGA TTTGGAAAAA CTGGCATTAT TGATTATGGA ATCCGTCTCA 420
ATAGGAGTGA AAGATGGGAT GCCTATTGCT ACAACCCACA CGCAAAGGAG TGTGGTGGCG 480
TCTTTACAGA TCCAAAGCGA ATTTTTAAAT CTCCAGGCTT CCCAAATGAG TACGAAGATA 540
ACCAAATCTG CTACTGGCAC ATTAGACTCA AGTATGGTCA GCGTATTCAC CTGAGTTTTT 600
TAGATTTTGA CCTTGAAGAT GACCCAGGTT GCTTGGCTGA TTATGTTGAA ATATATGACA 660
GTTACGATGA TGTCCATGGC TTTGTGGGAA GATACTGTGG AGATGAGCTT CCAGATGACA 720
TCATCAGTAC AGGAAATGTC ATGACCTTGA AGTTTCTAAG TGATGCTTCA GTGACAGCTG 780
GAGGTTTCCA AATCAAATAT GTTGCAATGG ATCCTGTATC CAAATCCAGT CAAGGAAAAA 840
ATACAAGTAC TACTTCTACT GGAAATAAAA ACTTTTTAGC TGGAAGATTT AGCCACTTAT 900
AAAAAAAAAA AAGGATGATC AAAACACACA GTGTTTATGT TGGAATCTTT TGGAACTCCT 960
TTGATCTCAC TGTTATTATT AACATTTATT TATTATTTTT CTAAATGTGA AAGAAATACA 1020
TAATTTAGGG AAAATTGGAA AATATAGGAA ACTTTAAACG AGAAAATGAA ACCTCTCATA 1080
ATCCCACTGC ATAGAAATAA CAAGCGTTAA CATTTTCATA TTTTTTTCTT TCAGTCATTT 1140
TTGTATTTGT GGTATATGTA TATATGTACC TATATGTATT TGCATTTGAA ATTTTGGAAT 1200
CCTGCTCTAT GTACAGTTTT GTATTATACT TTTTAAATCT TGAACTTTAT GAACATTTTC 1260
TGAAATCATT GATTATTCTA CAAAAACATG ATTTTAAACA GCTGTAAAAT ATTCTATGAT 1320
ATGAATGTTT TATGCATTAT TTAAGCCTGT CTCTATTGTT GGAATTTCAG GTCATTTTCA 1380 TAAATATTGT TGCAATAAAT ATCCTTCGGA ATTC
Seq ID NO: 294 Protein sequence Protein Accession ft: NP_009046.1
1 11 21 31 41 51
I I I I I I
MIILIYLFLL LWEDTQGWGF KDGIFHNSIW LERAAGVYHR EARSGKYKLT YAEAKAVCEF 60
EGGHLATYKQ LEAARKIGFH VCAAGWMAKG RVGYPIVKPG PNXXFGKTGI IDYGIRLNRS 120
ERWDAYCYNP HAKECGGVFT DPKRIFKSPG FPNEYEDNQI CYWHIRLKYG QRIHLSFLDF 180
DLEDDPGCLA DYVEIYDSYD DVHGFVGRYC GDELPDDIIS TGNVMTLKFL SDASVTAGGF 240 QIKYVAMDPV SKSSQGKNTS TTSTGNKNFL AGRFSHL
Seq ID NO: 295 DNA sequence
Nucleic Acid Accession #: NM_001218.2
Coding sequence: 116..1180
1 11 21 31 41 51
I I I I I I
GTACTCGCCA CGGCACCCAG GCTGCGCGCA CGCGGTCCCG GTGTGCAGCT GGAGAGCGAG 60
CGGCCACCGG GAGCCCCCGG CACAGCCCGC GCCCGCCCCG CAGGAGCCCG CGAAGATGCC 120
CCGGCGCAGC CTGCAGGCGG CGGCCGTGCT CCTGCTGGTG ATCTTAAAGG AACAGCCTTC 180
CAGCCCGGCC CCAGTGAACβ GTTCCAAGTG GAGTTATTTT GGTCCTGATG GGGAGAATAG 240
CTGGTCCAAG AAGTACCCGT CGTGTGGGGG CCTGCTGCAG TCCCCCATAG ACCTGCACAG 300
TGACATCCTC CAGTATGACG CCAGCCTCAC GCCCCTCGAG TTCCAAGGCT ACAATCTGTC 360
TGCCAACAAG CAGTTTCTCC TGACCAACAA TGGCCATTCA GTGAAGCTGA ACCTGCCCTC 420
GGACATGCAC ATCCAGGGCC TCCAGTCTCG CTACAGTGCC ACGCAGCTGC ACCTGCACTG 480
GGGGAACCCG AATGACCCGC ACGGCTCTGA GCACACCGTC AGCGGACAGC ACTTCGCCGC 540
CGAGCTGCAC ATTGTCCATT ATAACTCAGA CCTTTATCCT GACGCCAGCA CTGCCAGCAA 600
CAAGTCAGAA GGCCTCGCTG TCCTGGCTGT TCTCATTGAG ATGGGCTCCT TCAATCCGTC 660
CTATGACAAG ATCTTCAGTC ACCTTCAACA TGTAAAGTAC AAAGGCCAGG AAGCATTCGT 720
CCCGGGATTC AACATTGAAG AGCTGCTTCC GGAGAGGACC GCTGAATATT ACCGCTACCG 780
GGGGTCCCTG ACCACACCCC CTTGCAACCC CACTGTGCTC TGGACAGTTT TCCGAAACCC 840
CGTGCAAATT TCCCAGGAGC AGCTGCTGGC TTTGGAGACA GCCCTGTACT GCACACACAT 900 GGACGACCCT TCCCCCAGAG AAATGATCAA CAACTTCCGG CAGGTCCAGA AGTTCGATGA 960 GAGGCTGGTA TACACCTCCT TCTCCCAAGT GCAAGTCTGT ACTGCGGCAG GACTGAGTCT 1020 GGGCATCATC CTCTCACTGG CCCTGGCTGG CATTCTTGGC ATCTGTATTG TGGTGGTGGT 1080 GTCCATTTGG CTTTTCAGAA GGAAGAGTAT CAAAAAAGGT GATAACAAGG GAGTCATTTA 1140 CAAGCCAGCC ACCAAGATGG AGACTGAGGC CCACGCTTGA GGTCCCCGGA GCTCCCGGGC 1200 ACATCCAGGA AGGACCTTGC TTTGGACCCT ACACACTTCG GCTCTCTGGA CACTTGCGAC 1260 ACCTCAAGGT GTTCTCTGTA GCTCAATCTG CAAACATGCC AGGCCTCAGG GATCCTCTGC 1320 TGGGTGCCTC CTTGCCTTGG GACCATGGCC ACCCCAGAGC CATCCGATCG ATGGATGGGA 1380 TGCACTCTCA GACCAAGCAG CAGGAATTCA AAGCTGCTTG CTGTAACTGT GTGAGATTGT 1440 GAAGTGGTCT GAATTCTGGA ATCACAAACC AAGCCATGCT GGTGGGCCAT TAATGGTTGG 1500 AAAACACTTT CATCCGGGGC TTTGCCAGAG CGTGCTTTCA AGTGTCCTGG AAAGTCTGCT 1560 GCTTCTCCAA GCTTTCAGAC AAGAATGTGC ACTCTCTGCT TAGGTTTTGC TTGGGAAACT 1620 CAACTTCTTT CCTCTGGAGA CGGGGCATCT CCCTCTGATT TCCTTCTGCT ATGACAAAAC 1680 CTTTAATCTG CACCTTACAA CTCGGGGACA AATGGGGACA GGAAGGATCA AGTTGTAGAG 1740 AGAAAAAAGA AAACAAGAGA TATACATTGT GATATATTAG GGACACTTTC ACAGTCCTGT 1800 CCTCTGGATC ACAGACACTG CACAGACCTT AGGGAATGGC AGGTTCAAGT TCCACTTCTT 1860 GGTGGGGATG AGAAGGGAGA GAGAGCTAGA GGGACAAAGA GAATGAGAAG ACATGGATGA 1920 TCTGGGAGAG TCTCACTTTG GAATCAGAAT TGGAATCACA TTCTGTTTAT CAAGCCATAA 1980 TGTAAGGACA GAATAATACA ATATTAAGTC CAAATCCAAC CTCCTGTCAG TGGAGCAGTT 2040 ATGTTTTATA CTCTACAGAT TTTACAAATA ATGAGGCTGT TCCTTGAAAA TGTGTTGTTG 2100 CTGTGTCCTG GAGGAGACAT GAGTTCCGAG ATGACCCAAT CTGCCTTTGA ATCTGGAGGA 2160 AATAGGCAGA AACAAAATGA CTGTAGAACT TATTCTCTGT AGGCCAAATT TCATTTCAGC 2220 CACTTCTGCA GGATCCCTAC TGCCAACCTG GAATGGAGAC TTTTATCTAC TTCTCTCTCT 2280 CTGAAGATGT CAAATCGTGG TTTAGATCAA ATATATTTCA AGCTATAAAA GCAGGAGGTT 2340 ATCTGTGCAG GGGGCTGGCA TCATGTATTT AGGGGCAAGT AATAATGGAA TGCTACTAAG 2400 ATACTCCATA TTCTTCCCCG AATCACACAG ACAGTTTCTG ACAGGCGCAA CTCCTCCATT 2460 TTCCTCCCGC AGGTGAGAAC CCTGTGGAGA TGAGTCAGTG CCATGACTGA GAAGGAACCG 2520 ACCCCTAGTT GAGAGCACCT TGCAGTTCCC CGAGAACTTT CTGATTCACA GTCTCATTTT 2580 GACAGCATGA AATGTCCTCT TGAAGCATAG CTTTTTAAAT ATCTTTTTCC TTCTACTCCT 2640 CCCTCTGACT CTAAGAATTC TCTCTTCTGG AATCGCTTGA ACCCAGGAGG CGGAGGTTGC 2700 AGTAAGCCAA GGTCATGCCA CTGCACTCTA GCCTGGGTGA CAGAGCGAGA CTCCATCTCA 2760 AAAAAAAAAA AAAAA
Seq ID NO: 296 Protein sequence Protein Accession #: NP 001209.1
11 21 31 41 51
I I I I I
MPRRSLHAAA VLLLVILKEQ PSSPAPVNGS KWTYFGPDGE NSWSKKYPSC GGLLQSPIDL 60 HSDILQYDAS LTPLEFQGYN LSANKQFLLT NNGHSVKLNL PSDMHIQGLQ SRYSATQLHL 120 HWGNPNDPHG SEHTVSGQHF AAELHIVHYN SDLYPDASTA SNKSEGLAVL AVLIEMGSFN 180 PSYDKIFSHL QHVKYKGQEA FVPGFNIEEL LPERTAEYYR YRGSLTTPPC NPTVLWTVFR 240 NPVQISQEQL LALETALYCT HMDDPSPREM INNFRQVQKF DERLVYTSFS QVQVCTAAGL 300 SLGIILSLAL AGILGICIW WSIWLFRRK SIKKGDNKGV IYKPATKMET EAHA
Seq ID NO: 297 DNA sequence
Nucleic Acid Accession #: NM_006632.1
Coding sequence: 377..1582
11 21 31 41 51
ACGCGTCCGC CCACGCGTCC GCCCACGCGT CCGGTCGGGG CCAGAGCGCA GGTGTACCTG 60 GCGGCCGTGC TGGAGCACCT GACCGCCGAG ATCCTGGAGC TGGCTGGCAA CCCGGCCCGC 120 GACAAGAAGA CCCGCATCAT CCTGCGCCAC CTGTAGCTGG CCATTCGCAA CGGCGAGGAG 180 CTTAACAAGC TGCTGGGCGA AGTCACCATC GCGCAGGGCG GTGTCCTGCC CAACATTCAG 240 GGCGTGCTTC TGCCCCAGAA GACCAAGAGC CACCACAAGG CCAAGGGTGA AAACCATTCA 300 CTAGGAGAGG AGAAACACAA TGGCCACCAA GACAGAGTTG AGTCCCACAG CAAGGGAGAG 360 CAAGAACGCA CAAGATATGC AAGTGGATGA GACACTGATC CCCAGGAAAG GTCCAAGTTT 420 ATGTTCTGCT CGCTATGGAA TAGCCCTCGT CTTACATTTC TGCAATTTCA CAACGATAGC 480 ACAAAATGTC ATCATGAACA TCACCATGGT AGCCATGGTC AACAGCACAA GCCCTCAATC 540 CCAGCTCAAT GATTCCTCTG AGGTGCTGCC TGTTGACTCA TTTGGTGGCC TAAGTAAAGC 600 CCCAAAGAGT CTTCCTGCAA AGTCCTCAAT ACTTGGGGGT CAGTTTGCAA TTTGGGAAAA 660 GTGGGGCCCT CCACAAGAAC GAAGCAGACT CTGCAGCATT GCTTTATCAG GAATGTTACT 720 GGGATGCTTT ACTGCCATCC TCATAGGTGG CTTCATTAGT GAAACCCTTG GGTGGCCCTT 780 TGTCTTCTAT ATCTTTGGAG GTGTTGGCTG TGTCTGCTGC CTTCTCTGGT TTGTTGTGAT 840 TTATGATGAC CCCTTTTCCT ATCCATGGAT AAGCACCTCA GAAAAAGAAT ACATCATATC 900 CTCCTTGAAA CAACAGGTCG GGTCTTCTAA GCAGCCTCTT CCCATCAAAG CTATGCTCAG 960 ATCTCTACCC ATTTGGTCCA TATGTTTAGG CTGTTTCAGC CATCAATGGT TAGTTAGCAC 1020 AATGGTTGTA TACATACCAA CTTACATCAG CTCTGTGTAC CATGTTAACA TCAGAGACAA 1080 TGGACTTCTA TCTGCCCTTC CTTTTATTGT TGCCTGGGTC ATAGGCATGG TGGGAGGCTA 1140 TCTGGCAGAT TTCCTTCTAA CCAAAAAGTT TAGACTCATC ACTGTGAGGA AAATTGCCAC 1200 AATTTTAGGA AGTCTCCCCT CTTCAGCACT CATTGTGTCT CTGCCTTACC TCAATTCCGG 1260 CTATATCACA GCAACTGCCT TGCTGACGCT CTCTTGCGGA TTAAGCACAT TGTGTCAGTC 1320 AGGGATTTAT ATCAATGTCT TAGATATTGC TCCAAGGTAT TCCAGTTTTC TCATGGGAGC 1380 ATCAAGAGGA TTTTCGAGCA TAGCACCTGT CATTGTACCC ACTGTCAGCG GATTTCTTCT 1440 TAGTCAGGAC CCTGAGTTTG GGTGGAGGAA TGTCTTCTTC TTGCTGTTTG CCGTTAACCT 1500 GTTAGGACTA CTCTTCTACC TCATATTTGG AGAAGCAGAT GTCCAAGAAT GGGCTAAAGA 1560 GAGAAAACTC ACTCGTTTAT GAAGTTATCC CACCTTGGAT GGAAAAGTCA TTAGGCACCG 1620 TATTGCATAA AATAGAAGGC TTCCGTGATG AAAATACCAG TGAAAAGATT TTTTTTTCCT 1680 GTGGCTCTTT TCAATTATGA GATCAGTTCA TTATTTTATT CAGACTTTTT TTTGAGAGAA 1740 ATGTAAGATG AATAAAAATT CAAATAAAAT GATAACTAAG AAAAAAAAAA AAAAA
Seq ID NO: 298 Protein sequence Protein Accession ft: NP 006623.1 11 21 31 41 51
I I I I I
MQVDETLIPR KGPSLCSARY GIALVLHFCN FTTIAQNVIM NITMVAMVNS TSPQSQLNDS 60 SEVLPVDSFG GLSKAPKSLP AKSSILGGQF AIWEKWGPPQ ERSRLCSIAL SGMLLGCFTA 120 ILIGGFISET LGWPFVFYIF GGVGCVCCLL WFWIYDDPF SYPWISTSEK EYIIΞSLKQQ 180 VGSSKQPLPI KAMLRΞLPIW SICLGCFSHQ WLVSTMWYI PTYISSVYHV NIRDNGLLSA 240 LPFIVAWVIG MVGGYLADFL LTKKFRLITV RKIATILGSL PSSALIVSLP YLNSGYITAT 300 ALLTLSCGLS TLCQSGIYIN VLDIAPRYSS FLMGASRGFS SIAPVIVPTV SGFLLSQDPE 360 FGWRNVFFLL FAVNLLGLLF YLIFGEADVQ EWAKERKLTR L
Seq ID NO: 299 DNA sequence
Nucleic Acid Accession #: NM_003058.1
Coding sequence: 145..1812
11 21 31 41 51
I I I I I
GGCCCTGCCC TGAAGGCTGG TCACTTGCAG AGGTAAACTC CCCTCTTTGA CTTCTGGCCA 60
GGGTTTGTGC TGAGCTGGCT GCAGCCGCTC TCAGCCTCGC TCCGGGCACG TCGGGCAGCC 120
TCGGGCCCTC CTGCCTGCAG GATCATGCCC ACCACCGTGG ACGATGTCCT GGAGCATGGA 180
GGGGAGTTTC ACTTTTTCCA GAAGCAAATG TTTTTCCTCT TGGCTCTGCT CTCGGCTACC 240
TTCGCGCCCA TCTACGTGGG CATCGTCTTC CTGGGCTTCA CCCCTGACCA CCGCTGCCGG 300
AGCCCCGGAG TGGCCGAGCT GAGTCTGCGC TGCGGCTGGA GTCCTGCAGA GGAACTGAAC 360
TACACGGTGC CGGGCCCAGG ACCTGCGGGC GAAGCCTCCC CAAGACAGTG TAGGCGCTAC 420
GAGGTGGACT GGAACCAGAG CACCTTTGAC TGCGTGGACC CCCTGGCCAG CCTGGACACC 480
AACAGGAGCC GCCTGCCACT GGGCCCCTGC CGGGACGGCT GGGTGTACGA GACGCCTGGC 540
TCGTCCATCG TCACCGAGTT TAACCTGGTA TGTGCCAACT CCTGGATGTT GGACCTATTC 600
CAGTCATCAG TGAATGTAGG ATTCTTTATT GGCTCTATGA GTATCGGCTA CATAGCAGAC 660
AGGTTTGGCC GTAAGCTCTG CCTCCTAACT ACAGTCCTCA TAAATGCTGC AGCTGGAGTT 720
CTCATGGCCA TTTCCCCAAC CTATACGTGG ATGTTAATTT TTCGCTTAAT CCAAGGACTG 780
GTCAGCAAAG CAGGCTGGTT AATAGGCTAC ATCCTGATTA CAGAATTTGT TGGGCGGAGA 840
TATCGGAGAA CAGTGGGGAT TTTTTACCAA GTTGCCTATA CAGTTGGGCT CCTGGTGCTA 900
GCTGGGGTGG CTTACGCACT TCCTCACTGG AGGTGGTTGC AGTTCACAGT TGCTCTGCCC 960
AACTTCTTCT TCTTGCTCTA TTACTGGTGC ATACCTGAGT CTCCCAGGTG GCTGATCTCC 1020
CAGAATAAGA ATGCTGAAGC CATGAGAATC ATTAAGCACA TCGCAAAGAA AAATGGAAAA 1080
TCTCTACCCG CCTCCCTTCA GCGCCTGAGA CTTGAAGAGG AAACTGGCAA GAAATTGAAC 1140
CCTTCATTTC TTGACTTGGT CAGAACTCCT CAGATAAGGA AACATACTAT GATATTGATG 1200
TACAACTGGT TCACGAGCTC TGTGCTCTAC CAGGGCCTCA TCATGCACAT GGGCCTTGCA 1260
GGTGACAATA TCTACCTGGA TTTCTTCTAC TCTGCCCTGG TTGAATTCCC AGCTGCCTTC 1320
ATGATCATCC TCACCATCGA CCGCATCGGA CGCCGTTACC CTTGGGCTGC ATCAAATATG 1380
GTTGCAGGGG CAGCCTGTCT GGCCTCAGTT TTTATACCTG GTGATCTACA ATGGCTAAAA 1440
ATTATTATCT CATGCTTGGG AAGAATGGGG ATCACAATGG CCTATGAGAT AGTCTGCCTG 1500
GTCAATGCTG AGCTGTACCC CACATTCATT AGGAATCTTG GCGTCCACAT CTGTTCCTCA 1560
ATGTGTGACA TTGGTGGCAT CATCACGCCA TTCCTGGTCT ACCGGCTCAC TAACATCTGG 1620
CTTGAGCTCC CGCTGATGGT TTTCGGCGTA CTTGGCTTGG TTGCTGGAGG TCTGGTGCTG 1680
TTGCTTCCAG AAACTAAAGG GAAAGCTTTG CCTGAGACCA TCGAGGAAGC CGAAAATATG 1740
CAAAGACCAA GAAAAAATAA AGAAAAGATG ATTTACCTCC AAGTTCAGAA ACTAGACATT 1800
CCATTGAACT AAGAAGAGAG ACCGTTGCTG CTGTCATGAC CTAGCTTTGA TGGCAGCAAG 1860
ACCAAAAGTA GAAATCCCTG CACTCATCAC AAAGCCCATA CAACTCAACC AAACTTACCC 1920
CTGAGCCCTA TCAACCTAGG TCTACAGCCA GTGGAGTCTA TTGTACACTG TGGAAAAATA 1980
CCCATGGGAC CAGATCCTGC CAAATTCTTC CAGCTCACTT TATTCTCAGC ATTCCTAGGA 2040
CATTGGACAT TGGTTTTCTG GAGGGTTTTT TTTCCGATCT TTGTATTTTT TTAAATTTGA 2100
TTCTTTTCTT TGCAATGCTA GCAACCAGAA TACATAGGGG AACTGTGGGC TAGGCAAANA 2160
AAATAGAAAA AGTGTGAAAA ACAGTAAAGT TGGGAGAGGA GCATCTATTT TCTTAAAGAA 2220
ATAAAACACC NAAAACAAAA AAAAAAAAAA AAAAAAA
Seq ID NO: 300 Protein sequence Protein Accesεion ft: NP 003049.1
11 21 31 41 51
I I I I I
MPTTVDDVLE HGGEFHFFQK QMFFLLALLS ATFAPIYVGI VFLGFTPDHR CRSPGVAELS 60 LRCGWSPAEE LNYTVPGPGP AGEASPRQCR RYEVDWNQST FDCVDPLASL DTNRSRLPLG 120 PCRDGWVYET PGSSIVTEFN LVCANSWMLD LFQSSVNVGF FIGSMSIGYI ADRFGRKLCL 180 LTTVLINAAA GVLMAISPTY TWMLIFRLIQ GLVSKAGWLI GYILITEFVG RRYRRTVGIF 240 YQVAYTVGLL VLAGVAYALP HWRWLQFTVA LPNFFFLLYY WCIPESPRWL ISQNKNAEAM 300 RIIKHIAKKN GKSLPASLQR LRLEEETGKK LNPSFLDLVR TPQIRKHTMI LMYNWFTSSV 360 LYQGLIMHMG LAGDNIYLDF FYSALVEFPA AFMIILTIDR IGRRYPWAAS NMVAGAACLA 420 SVFIPGDLQW LKIIISCLGR MGITMAYEIV CLVNAELYPT FIRNLGVHIC SSMCDIGGII 480 TPFLVYRLTN IWLELPLMVF GVLGLVAGGL VLLLPETKGK ALPETIEEAE NMQRPRKNKE 540 KMIYLQVQKL DIPLN
Seq ID NO: 301 DNA εequence
Nucleic Acid Acceεεion ft: NM_012206.1
Coding sequence: 52..1131
11 21 31 41 51
I I I I I
GTTACCCAGC ATTGTGAGTG ACAGAGCCTG GATCTGAACG CTGATCCCAT AATGCATCCT 60 CAAGTGGTCA TCTTAAGCCT CATCCTACAT CTGGCAGATT CTGTAGCTGG TTCTGTAAAG 120 GTTGGTGGAG AGGCAGGTCC ATCTGTCACA CTACCCTGCC ACTACAGTGG AGCTGTCACA 180 TCAATGTGCT GGAATAGAGG CTCATGTTCT CTATTCACAT GCCAAAATGG CATTGTCTGG 240 ACCAATGGAA CCCACGTCAC CTATCGGAAG GACACACGCT ATAAGCTATT GGGGGACCTT 300 TCAAGAAGGG ATGTCTCTTT GACCATAGAA AATACAGCTG TGTCTGACAG TGGCGTATAT 360 TGTTGCCGTG TTGAGCACCG TGGGTGGTTC AATGACATGA AAATCACCGT ATCATTGGAG 420 ATTGTGCCAC CCAAGGTCAC GACTACTCCA ATTGTCACAA CTGTTCCAAC CGTCACGACT 480 GTTCGAACGA GCACCACTGT TCCAACGACA ACGACTGTTC CAACGACAAC TGTTCCAACA 540 ACAATGAGCA TTCCAACGAC AACGACTGTT CCGACGACAA TGACTGTTTC AACGACAACG 600 AGCGTTCCAA CGACAACGAG CATTCCAACA ACAACAAGTG TTCCAGTGAC AACAACGGTC 660 TCTACCTTTG TTCCTCCAAT GCCTTTGCCC AGGCAGAACC ATGAACCAGT AGCCACTTCA 720 CCATCTTCAC CTCAGCCAGC AGAAACCCAC CCTACGACAC TGCAGGGAGC AATAAGGAGA 780 GAACCCACCA GCTCACCATT GTACTCTTAC ACAACAGATG GGAATGACAC CGTGACAGAG 840 TCTTCAGATG GCCTTTGGAA TAACAATCAA ACTCAACTGT TCCTAGAACA TAGTCTACTG 900 ACGGCCAATA CCACTAAAGG AATCTATGCT GGAGTCTGTA TTTCTGTCTT GGTGCTTCTT 960 GCTCTTTTGG GTGTCATCAT TGCCAAAAAG TATTTCTTCA AAAAGGAGGT TCAACAACTA 1020 AGTGTTTCAT TTAGCAGCCT TCAAATTAAA GCTTTGCAAA ATGCAGTTGA AAAGGAAGTC 1080 CAAGCAGAAG ACAATATCTA CATTGAGAAT AGTCTTTATG CCACGGACTA AGACCCAGTG 1140 GTGCTCTTTG AGAGTTTACG CCCATGACTG CAGAAGACTG AACAGGTATC AGCACATCAG 1200 ATGTCTTTTA GACTCCAAGA CAATTTTTCT GTTTCAGTTT CATCTGGCAT TCCAACATGT 1260 CAGTGATACT GGGTAGAGTA ACTCTCCCAC TCCAAA.CTGT GTATAGTCAA CCTCATCATT 1320 AATGTAGTCC TAATTTGTTT TGCTAAAACT GGCTCAATCC TTCTGATCAT TGCAGAGTTT 1380 TCTCTCAAAC ATGAACACTT TAGAATTGTA TGTTCTCTTT AGACCCCATA AATCCTGTAT
Seq ID NO: 302 Protein sequence Protein Accession #: NP_036338.1
11 21 31 41 51
I I I I I
MHPQWILSL ILHLADSVAG SVKVGGEAGP SVTLPCHYSG AVTSMCWNRG SCSLFTCQNG 60 IVWTNGTHVT YRKDTRYKLL GDLSRRDVSL TIENTAVSDS GVYCCRVEHR GWFNDMKITV 120 SLEIVPPKVT TTPIVTTVPT VTTVRTSTTV PTTTTVPTTT VPTTMSIPTT TTVPTTMTVS 180 TTTSVPTTTS IPTTTSVPVT TTVSTFVPPM PLPRQNHEPV ATSPSSPQPA ETHPTTLQGA 240 IRREPTSSPL YSYTTDGNDT VTESSDGLWN NNQTQLFLEH SLLTANTTKG IYAGVCISVL 300 VLLALLGVII AKKYFFKKEV QQLSVSFSSL QIKALQNAVE KEVQAEDNIY IENSLYATD
Seq ID NO: 303 DNA sequence
Nucleic Acid Accession ft: NM_001044.1
Coding sequence: 129..1991
11 21 31 41 51
I I I I I
ACCGCTCCGG AGCGGGAGGG GAGGCTTCGC GGAACGCTCT CGGCGCCAGG ACTCGCGTGC 60
AAAGCCCAGG CCCGGGCGGC CAGACCAAGA GGGAAGAAGC ACAGAATTCC TCAACTCCCA 120
GTGTGCCCAT GAGTAAGAGC AAATGCTCCG TGGGACTCAT GTCTTCCGTG GTGGCCCCGG 180
CTAAGGAGCC CAATGCCGTG GGCCCGAAGG AGGTGGAGCT CATCCTTGTC AAGGAGCAGA 240
ACGGAGTGCA GCTCACCAGC TCCACCCTCA CCAACCCGCG GCAGAGCCCC GTGGAGGCCC 300
AGGATCGGGA GACCTGGGGC AAGAAGATCG ACTTTCTCCT GTCCGTCATT GGCTTTGCTG 360
TGGACCTGGC CAACGTCTGG CGGTTCCCCT ACCTGTGCTA CAAAAATGGT GGCGGTGCCT 420
TCCTGGTCCC CTACCTGCTC TTCATGGTCA TTGCTGGGAT GCCACTTTTC TACATGGAGC 480
TGGCCCTCGG CCAGTTCAAC AGGGAAGGGG CCGCTGGTGT CTGGAAGATC TGCCCCATAC 540
TGAAAGGTGT GGGCTTCACG GTCATCCTCA TCTCACTGTA TGTCGGCTTC TTCTACAACG 600
TCATCATCGC CTGGGCGCTG CACTATCTCT TCTCCTCCTT CACCACGGAG CTCCCCTGGA 660
TCCACTGCAA CAACTCCTGG AACAGCCCCA ACTGCTCGGA TGCCCATCCT GGTGACTCCA 720
GTGGAGACAG CTCGGGCCTC AACGACACTT TTGGGACCAC ACCTGCTGCC GAGTACTTTG 780
AACGTGGCGT GCTGCACCTC CACCAGAGCC ATGGCATCGA CGACCTGGGG CCTCCGCGGT 840
GGCAGCTCAC AGCCTGCCTG GTGCTGGTCA TCGTGCTGCT CTACTTCAGC CTCTGGAAGG 900
GCGTGAAGAC CTCAGGGAAG GTGGTATGGA TCACAGCCAC CATGCCATAC GTGGTCCTCA 960
CTGCCCTGCT CCTGCGTGGG GTCACCCTCC CTGGAGCCAT AGACGGCATC AGAGCATACC 1020
TGAGCGTTGA CTTCTACCGG CTCTGCGAGG CGTCTGTTTG GATTGACGCG GCCACCCAGG 1080
TGTGCTTCTC CCTGGGCGTG GGGTTCGGGG TGCTGATCGC CTTCTCCAGC TACAACAAGT 1140
TCACCAACAA CTGCTACAGG GACGCGATTG TCACCACCTC CATCAACTCC CTGACGAGCT 1200
TCTCCTCCGG CTTCGTCGTC TTCTCCTTCC TGGGGTACAT GGCACAGAAG CACAGTGTGC 1260
CCATCGGGGA CGTGGCCAAG GACGGGCCAG GGCTGATCTT CATCATCTAC CCGGAAGCCA 1320
TCGCCACGCT CCCTCTGTCC TCAGCCTGGG CCGTGGTCTT CTTCATCATG CTGCTCACCC 1380
TGGGTATCGA CAGCGCCATG GGTGGTATGG AGTCAGTGAT CACCGGGCTC ATCGATGAGT 1440
TCCAGCTGCT GCACAGACAC CGTGAGCTCT TCACGCTCTT CATCGTCCTG GCGACCTTCC 1500
TCCTGTCCCT GTTCTGCGTC ACCAACGGTG GCATCTACGT CTTCACGCTC CTGGACCATT 1560
TTGCAGCCGG CACGTCCATC CTCTTTGGAG TGCTCATCGA AGCCATCGGA GTGGCCTGGT 1620
TCTATGGTGT TGGGCAGTTC AGCGACGACA TCCAGCAGAT GACCGGGCAG CGGCCCAGCC 1680
TGTACTGGCG GCTGTGCTGG AAGCTGGTCA GCCCCTGCTT TCTCCTGTTC GTGGTCGTGG 1740
TCAGCATTGT GACCTTCAGA CCCCCCCACT ACGGAGCCTA CATCTTCCCC GACTGGGCCA 1800
ACGCGCTGGG CTGGGTCATC GCCACATCCT CCATGGCCAT GGTGCCCATC TATGCGGCCT 1860
ACAAGTTCTG CAGCCTGCCT GGGTCCTTTC GAGAGAAACT GGGCTACGCC ATTGCACCCG 1920
AGAAGGACCG TGAGCTGGTG GACAGAGGGG AGGTGCGCCA GTTCACGCTC CGCCACTGGC 1980
TCAAGGTGTA GAGGGAGCAG AGACGAAGAC CCCAGGAAGT CATCCTGCAA TGGGAGAGAC 2040
ACGAACAAAC CAAGGAAATC TAAGTTTCGA GAGAAAGGAG GGCAACTTCT ACTCTTCAAC 2100
CTCTACTGAA AACACAAACA ACAAAGCAGA AGACTCCTCT CTTCTGACTG TTTACACCTT 2160
TCCGTGCCGG GAGCGCACCT CGCCGTGTCT TGTGTTGCTG TAATAACGAC GTAGATCTGT 2220
GCAGCGAGGT CCACCCCGTT GTTGTCCCTG CAGGGCAGAA AAACGTCTAA CTTCATGCTG 2280
TCTGTGTGAG GCTCCCTCCC TCCCTGCTCC CTGCTCCCGG CTCTGAGGCT GCCCCAGGGG 2340
CACTGTGTTC TCAGGCGGGG ATCACGATCC TTGTAGACGC ACCTGCTGAG AATCCCCGTG 2400
CTCACAGTAG CTTCCTAGAC CATTTACTTT GCCCATATTA AAAAGCCAAG TGTCCTGCTT 2460
GGTTTAGCTG TGCAGAAGGT GAAATGGAGG AAACCACAAA TTCATGCAAA GTCCTTTCCC 2520
GATGCGTGGC TCCCAGCAGA GGCCGTAAAT TGAGCGTTCA GTTGACACAT TGCACACACA 2580
GTCTGTTCAG AGGCATTGGA GGATGGGGGT CCTGGTATGT CTCACCAGGA AATTCTGTTT 2640
ATGTTCTTGC AGCAGAGAGA AATAAAACTC CTTGAAACCA GCTCAGGCTA CTGCCACTCA 2700
GGCAGCCTGT GGGTCCTTGT GGTGTAGGGA ACGGCCTGAG AGGAGCGTGT CCTATCCCCG 2760
GACGCATGCA GGGCCCCCAC AGGAGCGTGT CCTATCCCCG GACGCATGCA GGGCCCCCAC 2820 AGGAGCATGT CCTATCCCTG GACGCATGCA GGGCCCCCAC AGGAGCGTGT ACTACCCCAG 2880 AACGCATGCA GGGCCCCCAC AGGAGCGTGT ACTACCCCAG GACGCATGCA GGGCCCCCAC 2940 TGGAGCGTGT ACTACCCCAG GACGCATGCA GGGCCCCCAC AGGAGCGTGT CCTATCCCCG 3000 GACCGGACGC ATGCAGGGCC CCCACAGGAG CGTGTACTAC CCCAGGACGC ATGCAGGGCC 3060 CCCAGAGGAG CGTGTACTAC CCCAGGATGC ATGCAGGGCC CCCACAGGAG CGTGTACTAC 3120 CCCAGGACGC ATGCAGGGCC CCCATGCAGG CAGCCTGCAG ACCAACACTC TGCCTGGCCT 3180 TGAGCCGTGA CCTCCAGGAA GGGACCCCAC TGGAATTTTA TTTCTCTCAG GTGCGTGCCA 3240 CATCAATAAC AACAGTTTTT ATGTTTGCGA ATGGCTTTTT AAAATCATAT TTACCTGTGA 3300 ATCAAAACAA ATTCAAGAAT GCAGTATCCG CGAGCCTGCT TGCTGATATT GCAGTTTTTG 3360 TTTACAAGAA TAATTAGCAA TACTGAGTGA AGGATGTTGG CCAAAAGCTG CTTTCCATGG 3420 CACACTGCCC TCTGCCACTG ACAGGAAAGT GGATGCCATA GTTTGAATTC ATGCCTCAAG 3480 TCGGTGGGCC TGCCTACGTG CTGCCCGAGG GCAGGGGCCG TGCAGGGCCA GTCATGGCTG 3540 TCCCCTGCAA GTGGACGTGG GCTCCAGGGA CTGGAGTGTA ATGCTCGGTG GGAGCCGTCA 3600 GCCTGTGAAC TGCCAGGCAG CTGCAGTTAG CACAGAGGAT GGCTTCCCCA TTGCCTTCTG 3660 GGGAGGGACA CAGAGGACGG CTTCCCCATC GCCTTCTGGC CGCTGCAGTC AGCACAGAGA 3720 GCGGCTTCCC CATTGCCTTC TGGGGAGGGA CACAGAGGAC AGTTTCCCCA TCGCCTTCTG 3780 GTTGTTGAAG ACAGCACAGA GAGCGGCTTC CCCATCGCCT TCTGGGGAGG GGCTCCGTGT 3840 AGCAACCCAG GTGTTGTCCG TGTCTGTTGA CCAATCTCTA TTCAGCATCG TGTGGGTCCC 3900 TAAGCACAAT AAAAGACATC CACAATGGAA AAAAAAAAAG GAATTC
Seq ID NO: 304 Protein sequence Protein Accession ft: NP 001035.1
1 11 21 31 41 51 1 1 I 1 1 1 | 1 11 | 1
MSKSKCSVGL MSSWAPAKE PNAVGPKEVE LILVKEQNGV QLTSSTLTNP RQSPVEAQDR 60
ETWGKKIDFL LSVIGFAVDL ANVWRFPYLC YKNGGGAFLV PYLLFMVIAG MPLFYMELAL 120
GQFNREGAAG VWKICPILKG VGFTVILISL YVGFFYNVII AWALHYLFSS FTTELPWIHC 180
NNSWNSPNCS DAHPGDSSGD SSGLNDTFGT TPAAEYFERG VLHLHQSHGI DDLGPPRWQL 240
TACLVLVIVL LYFSLWKGVK TSGKWWITA TMPYWLTAL LLRGVTLPGA IDGIRAYLSV 300
DFYRLCEASV WIDAATQVCF SLGVGFGVLI AFSSYNKFTN NCYRDAIVTT SINSLTSFSS 360
GFWFSFLGY MAQKHSVPIG DVAKDGPGLI FII PEAIAT LPLSSAWAW FFIMLLTLGI 420
DSAMGGMESV ITGLIDEFQL LHRHRELFTL FIVLATFLLS LFCVTNGGIY VFTLLDHFAA 480
GTSILFGVLI EAIGVAWFYG VGQFSDDIQQ MTGQRPSLYW RLCWKLVSPC FLLFWWSI 540
VTFRPPHYGA YIFPDWANAL GWVIATSSMA MVPI AAYKF CSLPGSFREK LAYAIAPEKD 600
RELVDRGEVR QFTLRHWLKV
Seq ID NO: 305 DNA sequence
Nucleic Acid Accession ft: NM_001216. Coding sequence: 43..1422
GCC 60
Figure imgf001071_0001
CTG 120
CTGTCACTGC TGCTTCTGAT GCCTGTCCAT CCCCAGAGGT TGCCCCGGAT GCAGGAGGAT 180
TCCCCCTTGG GAGGAGGCTC TTCTGGGGAA GATGACCCAC TGGGCGAGGA GGATCTGCCC 240
AGTGAAGAGG ATTCACCCAG AGAGGAGGAT CCACCCGGAG AGGAGGATCT ACCTGGAGAG 300
GAGGATCTAC CTGGAGAGGA GGATCTACCT GAAGTTAAGC CTAAATCAGA AGAAGAGGGC 360
TCCCTGAAGT TAGAGGATCT ACCTACTGTT GAGGCTCCTG GAGATCCTCA AGAACCCCAG 420
AATAATGCCC ACAGGGACAA AGAAGGGGAT GACCAGAGTC ATTGGCGCTA TGGAGGCGAC 480
CCGCCCTGGC CCCGGGTGTC CCCAGCCTGC GCGGGCCGCT TCCAGTCCCC GGTGGATATC 540
CGCCCCCAGC TCGCCGCCTT CTGCCCGGCC CTGCGCCCCC TGGAACTCCT GGGCTTCCAG 600
CTCCCGCCGC TCCCAGAACT GCGCCTGCGC AACAATGGCC ACAGTGTGCA ACTGACCCTG 660
CCTCCTGGGC TAGAGATGGC TCTGGGTCCC GGGCGGGAGT ACCGGGCTCT GCAGCTGCAT 720
CTGCACTGGG GGGCTGCAGG TCGTCCGGGC TCGGAGCACA CTGTGGAAGG CCACCGTTTC 780
CCTGCCGAGA TCCACGTGGT TCACCTCAGC ACCGCCTTTG CCAGAGTTGA CGAGGCCTTG 840
GGGCGCCCGG GAGGCCTGGC CGTGTTGGCC GCCTTTCTGG AGGAGGGCCC GGAAGAAAAC 900
AGTGCCTATG AGCAGTTGCT GTCTCGCTTG GAAGAAATCG CTGAGGAAGG CTCAGAGACT 960
CAGGTCCCAG GACTGGACAT ATCTGCACTC CTGCCCTCTG ACTTCAGCCG CTACTTCCAA 1020
TATGAGGGGT CTCTGACTAC ACCGCCCTGT GCCCAGGGTG TCATCTGGAC TGTGTTTAAC 1080
CAGACAGTGA TGCTGAGTGC TAAGCAGCTC CACACCCTCT CTGACACCCT GTGGGGACCT 1140
GGTGACTCTC GGCTACAGCT GAACTTCCGA GCGACGCAGC CTTTGAATGG GCGAGTGATT 1200
GAGGCCTCCT TCCCTGCTGG AGTGGACAGC AGTCCTCGGG CTGCTGAGCC AGTCCAGCTG 1260
AATTCCTGCC TGGCTGCTGG TGACATCCTA GCCCTGGTTT TTGGCCTCCT TTTTGCTGTC 1320
ACCAGCGTCG CGTTCCTTGT GCAGATGAGA AGGCAGCACA GAAGGGGAAC CAAAGGGGGT 1380
GTGAGCTACC GCCCAGCAGA GGTAGCCGAG ACTGGAGCCT AGAGGCTGGA TCTTGGAGAA 1440
TGTGAGAAGC CAGCCAGAGG CATCTGAGGG GGAGCCGGTA ACTGTCCTGT CCTGCTCATT 1500
ATGCCACTTC CTTTTAACTG CCAAGAAATT TTTTAAAATA AATATTTATA AT
Seq ID NO: 306 Protein sequence
Protein Accession ft: NP_001207.1
1 11 21 31 41 51 1 1 11 11 | 1 |1 | 1 MAPLCPSPWL PLLIPAPAPG LTVQLLLSLL LLMPVHPQRL PRMQEDSPLG GGSSGEDDPL 60
GEEDLPSEED SPREEDPPGE EDLPGEEDLP GEEDLPEVKP KSEEEGSLKL EDLPTVEAPG 120
DPQEPQNNAH RDKEGDDQSH WRYGGDPPWP RVSPACAGRF QSPVDIRPQL AAFCPALRPL 180
ELLGFQLPPL PELRLRNNGH SVQLTLPPGL EMALGPGREY RALQLHLHWG AAGRPGSEHT 240
VEGHRFPAEI HWHLSTAFA RVDEALGRPG GLAVLAAFLE EGPEENSAYE QLLSRLEEIA 300
EEGSETQVPG LDISALLPSD FSRYFQYEGS LTTPPCAQGV IWTVFNQTVM LSAKQLHTLS 360
DTLWGPGDSR LQLNFRATQP LNGRVIEASF PAGVDSSPRA AEPVQLNSCL AAGDILALVF 420
GLLFAVTSVA FLVQMRRQHR RGTKGGVSYR PAEVAETGA Seq ID NO: 307 DNA sequence
Nucleic Acid Accesεion ft: NM_003039.1
Coding sequence: 76..1581
1 11 21 31 41 51
I I I I I
CTTCTCTCTC CATTCAGTGC ACGCGTTACT TTGGCTAAAA GGAGGTGAGC GGCACTCTGC 60
CCTTCCAGAG CAAGCATGGA GCAACAGGAT CAGAGCATGA AGGAAGGGAG GCTGACGCTT 120
GTGCTTGCCC TGGCAACCCT GATAGCTGCC TTTGGGTCAT CCTTCCAGTA TGGGTACAAC 180
GTGGCTGCTG TCAACTCCCC AGCACTGCTC ATGCAACAAT TTTACAATGA GACTTACTAT 240
GGTAGGACCG GTGAATTCAT GGAAGACTTC CCCTTGACGT TGCTGTGGTC TGTAACCGTG 300
TCCATGTTTC CATTTGGAGG GTTTATCGGA TCCCTCCTGG TCGGCCCCTT GGTGAATAAA 360
TTTGGCAGAA AAGGGGCCTT GCTGTTCAAC AACATATTTT CTATCGTGCC TGCGATCTTA 420
ATGGGATGCA GCAGAGTCGC CACATCATTT GAGCTTATCA TTATTTCCAG ACTTTTGGTG 480
GGAATATGTG CAGGTGTATC TTCCAACGTG GTCCCCATGT ACTTAGGGGA GCTGGCCCCT 540
AAAAACCTGC GGGGGGCTCT CGGGGTGGTG CCCCAGCTCT TCATCACTGT TGGCATCCTT 600
GTGGCCCAGA TCTTTGGTCT TCGGAATCTC CTTGCAAACG TAGATGGCTG GCCGATCCTG 660
CTGGGGCTGA CCGGGGTCCC CGCGGCGCTG CAGCTCCTTC TGCTGCCCTT CTTCCCCGAG 720
AGCCCCAGGT ACCTGCTGAT TCAGAAGAAA GACGAAGCGG CCGCCAAGAA AGCCCTACAG 780
ACGCTGCGCG GCTGGGACTC TGTGGACAGG GAGGTGGCCG AGATCCGGCA GGAGGATGAG 840
GCAGAGAAGG CCGCGGGCTT CATCTCCGTG CTGAAGCTGT TCCGGATGCG CTCGCTGCGC 900
TGGCAGCTGC TGTCCATCAT CGTCCTCATG GGCGGCCAGC AGCTGTCGGG CGTCAACGCT 960
ATCTACTACT ACGCGGACCA GATCTACCTG AGCGCCGGCG TGCCGGAGGA GCACGTGCAG 1020
TACGTGACGG CCGGCACCGG GGCCGTGAAC GTGGTCATGA CCTTCTGCGC CGTGTTCGTG 1080
GTGGAGCTCC TGGGTCGGAG GCTGCTGCTG CTGCTGGGCT TCTCCATCTG CCTCATAGCC 1140
TGCTGCGTGC TCACTGCAGC TCTGGCACTG CAGGACACAG TGTCCTGGAT GCCATACATC 1200
AGCATCGTCT GTGTCATCTC CTACGTCATA GGACATGCCC TCGGGCCCAG TCCCATACCC 1260
GCGCTGCTCA TCACTGAGAT CTTCCTGCAG TCCTCTCGGC CATCTGCCTT CATGGTGGGG 1320
GGCAGTGTGC ACTGGCTCTC CAACTTCACC GTGGGCTTGA TCTTCCCGTT CATCCAGGAG 1380
GGCCTCGGCC CGTACAGCTT CATTGTCTTC GCCGTGATCT GCCTCCTCAC CACCATCTAC 1440
ATCTTCTTGA TTGTCCCGGA GACCAAGGCC AAGACGTTCA TAGAGATCAA CCAGATTTTC 1500
ACCAAGATGA ATAAGGTGTC TGAAGTGTAC CCGGAAAAGG AGGAACTGAA AGAGCTTCCA 1560
CCTGTCACTT CGGAACAGTG ACTCTGGAGA GGAAGCCAGT GGAGCTGGTC TGCCAGGGGC 1620
TTCCCACTTT GGCTTATTTT TCTGACTTCT AGCTGTCTGT GAATATCCAG AAATAAAACA 1680
ACTCTGATGT GGAATGCAGT CCTCATCTCC AGCCTCCCCA CCCCAGTGGG AACTGTGCAA 1740
AGGGCTGCCT TGCTGTTCTT GAAGCTGGGC TGTCTCTCTC CATGTTGGCC TGTCACCAGA 1800
CCCGAGTCAA TTAAACAGCT GGTCCTCCAC TTTGCTGGTT CAGCCTTCGT GTGGCTGCTG 1860
GTAACGTGGC TCCACCTTGA TGGGTCAACC TTTGTGTGGC TCCTGGTAAC ATAACAACAA 1920
CAGTTACTAT AGTGGTGAGA TGGAAGGAAT CAAATTTTGC CAGAGAAACT AACTCGGTGG 1980
CCCCAACAGG TCTTCCGGGG CCATGGGCAT TTGTTTAGAG CCAAATTCAT CCTCTTACCA 2040
GATCCTTTTC CAGAAATACC TGTCTAGGAA GGTGTGATGT CAGAAACAAT GACATCCAGA 2100
AAGCTGAGGA ACAGGTTCCT GTGGAGACAC TGAGTCAGAA TTCTTCATCC AAATTATTTT 2160
GTTAGTGGAA AATGGAATTG CTTCTGTGTA GTCAATAAAA TGAACCTGAT CACTTTTC
Seq ID NO: 308 Protein sequence Protein Accession ft: NP 003030.1
11 21 31 41 51
I I I I I
MEQQDQSMKE GRLTLVLALA TLIAAFGSSF QYGYNVAAVN SPALLMQQFY NETYYGRTGE 60 FMEDFPLTLL WSVTVSMFPF GGFIGSLLVG PLVNKFGRKG ALLFNNIFSI VPAILMGCSR 120 VATSFELIII SRLLVGICAG VSSNWPMYL GELAPKNLRG ALGWPQLFI TVGILVAQIF 180 GLRNLLANVD GWPILLGLTG VPAALQLLLL PFFPESPRYL LIQKKDEAAA KKALQTLRGW 240 DSVDREVAEI RQEDEAEKAA GFISVLKLFR MRSLRWQLLS IIVLMGGQQL SGVNAIYYYA 300 DQIYLSAGVP EEHVQYVTAG TGAVNWMTF CAVFWELLG RRLLLLLGFS ICLIACCVLT 360 AALALQDTVS WMPYISIVCV ISYVIGHALG PSPIPALLIT EIFLQSSRPS AFMVGGSVHW 420 LSNFTVGLIF PFIQEGLGPY SFIVFAVICL LTTIYIFLIV PETKAKTFIE INQIFTKMNK 480 VSEVYPEKEE LKELPPVTSE Q
Seq ID NO: 309 DNA sequence
Nucleic Acid Accession ft: NM_001252.1
Coding sequence: 138..719
11 21 31 41 51
I I I I I
GGCTGGTCCC CTGACAGGTT GAAGCAAGTA GACGCCCAGG AGCCCCGGGA GGGGGCTGCA 60 GTTTCCTTCC TTCCTTCTCG GCAGCGCTCC GCGCCCCCAT CGCCCCTCCT GCGCTAGCGG 120 AGGTGATCGC CGCGGCGATG CCGGAGGAGG GTTCGGGCTG CTCGGTGCGG CGCAGGCCCT 180 ATGGGTGCGT CCTGCGGGCT GCTTTGGTCC CATTGGTCGC GGGCTTGGTG ATCTGCCTCG 240 TGGTGTGCAT CCAGCGCTTC GCACAGGCTC AGCAGCAGCT GCCGCTCGAG TCACTTGGGT 300 GGGACGTAGC TGAGCTGCAG CTGAATCACA CAGGACCTCA GCAGGACCCC AGGCTATACT 360 GGCAGGGGGG CCCAGCACTG GGCCGCTCCT TCCTGCATGG ACCAGAGCTG GACAAGGGGC 420 AGCTACGTAT CCATCGTGAT GGCATCTACA TGGTACACAT CCAGGTGACG CTGGCCATCT 480 GCTCCTCCAC GACGGCCTCC AGGCACCACC CCACCACCCT GGCCGTGGGA ATCTGCTCTC 540 CCGCCTCCCG TAGCATCAGC CTGCTGCGTC TCAGCTTCCA CCAAGGTTGT ACCATTGCCT 600 CCCAGCGCCT GACGCCCCTG GCCCGAGGGG ACACACTCTG CACCAACCTC ACTGGGACAC 660 TTTTGCCTTC CCGAAACACT GATGAGACCT TCTTTGGAGT GCAGTGGGTG CGCCCCTGAC 720 CACTGCTGCT GATTAGGGTT TTTTAAATTT TATTTTATTT TATTTAAGTT CAAGAGAAAA 780 AGTGTACACA CAGGGGCCAC CCGGGGTTGG GGTGGGAGTG TGGTGGGGGG TAGTGGTGGC 840 AGGACAAGAG AAGGCATTGA GCTTTTTCTT TCATTTTCCT ATTAAAAA
Seq ID NO: 310 Protein sequence Protein Accession ft: NP 001243.1 1 11 21 31 41 51
I I I I I I
MPEEGSGCSV RRRPYGCVLR AALVPLVAGL VICLWCIQR FAQAQQQLPL ESLGWDVAEL 60 QLNHTGPQQD PRLYWQGGPA LGRSFLHGPE LDKGQLRIHR DGIYMVHIQV TLAICSSTTA 120 SRHHPTTLAV GICSPASRSI SLLRLSFHQG CTIASQRLTP LARGDTLCTN LTGTLLPSRN 180 TDETFFGVQW VRP
Seq ID NO: 311 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..3978
1 11 21 31 41 51
I I I I I I
ATGGTGGGTG AAGGACCCTA CCTTATCTCA GATCTGGACC AGCGAGGCCG GCGGAGATCC 60
TTTGCAGAAA GATATGACCC CAGCCTGAAG ACCATGATCC CAGTGCGACC CTGTGCAAGG 120
TTAGCACCCA ACCCGGTGGA TGATGCCGGG CTACTCTCCT TCGCCACATT TTCCTGGCTC 180
ACGCCGGTGA TGGTGAAAGG CTACCGGCAA AGGCTGACCG TAGACACCCT GCCCCCATTG 240
TCGACATATG ACTCATCTGA CACCAATGCC AAAAGATTTC GAGTCCTTTG GGATGAAGAG 300
GTAGCAAGGG TGGGTCCTGA GAAGGCCTCT CTGAGCCACG TGGTGTGGAA ATTCCAGAGG 360
ACACGCGTGT TGATGGACAT CGTGGCCAAC ATCCTGTGCA TCATCATGGC AGCCATAGGG 420
CCGACAGTTC TCATTCACCA AATCCTCCAG CAGACTGAGA GGACCTCTGG GAAAGTCTGG 480
GTTGGCATTG GACTGTGCAT AGCCCTTTTT GCCACCGAGT TTACCAAAGT CTTCTTTTGG 540
GCCCTTGCCT GGGCCATCAA CTACCGCACG GCCATCCGGT TGAAGGTGGC GCTCTCCACC 600
TTGGTTTTTG AAAACCTAGT GTCCTTCAAG ACATTGACCC ACATCTCTGT TGGCGAGGTG 660
CTCAATATAC TGTCAAGTGA TAGCTATTCT TTGTTTGAAG CTGCCTTGTT TTGTCCTTTG 720
CCAGCCACCA TCCCGATCCT AATGGTCTTT TGTGCGGCGT ACGCCTTTTT CATTCTGGGG 780
CCCACAGCTC TCATCGGGAT ATCAGTGTAT GTCATATTCA TACCCGTCCA GATGTTTATG 840
GCCAAGCTCA ATTCAGCTTT CCGAAGGTCA GCAATTTTGG TGACAGACAA GCGAGTTCAG 900
ACAATGAATG AGTTTCTGAC CTGCATCAGG CTGATCAAAA TGTATGCCTG GGAGAAATCT 960
TTTACCAACA CTATCCAAGA TATAAGAAGG AGGGAAAGAA AATTACTGGA AAAAGCTGGA 1020
TTTGTCCAAA GTGGAAACTC TGCCCTGGCC CCCATCGTGT CCACCATAGC CATCGTGCTG 1080
ACATTATCCT GCCACATCCT CCTGAGACGC AAACTCACCG CACCCGTGGC ATTTAGTGTG 1140
ATTGCCATGT TTAATGTAAT GAAGTTTTCC ATTGCAATCT TGCCCTTCTC CATCAAAGCA 1200
ATGGCTGAAG CGAATGTCTC TCTAAGGAGA ATGAAGAAAA TTCTCATAGA TAAAAGCCCC 1260
CCATCTTACA TCACCCAACC AGAAGACCCA GATACTGTCT TGCTTTTAGC AAATGCCACC 1320
TTGACATGGG AGCATGAAGC CAGCAGGAAA AGTACCCCAA AGAAATTGCA GAACCAGAAA 1380
AGGCATTTAT GCAAGAAACA GAGGTCAGAG GCATACAGTG AGAGGAGTCC ACCAGCCAAG 1440
GGAGCCACTG GCCCAGAGGA GCAAAGTGAC AGCCTCAAAT CGGTTCTGCA CAGCATAAGC 1500
TTTGTGGTGA GAAAGTTATG TCGTTATCCC GAAGCCCAGC TCCTGGCTTG GAGGTGGGCA 1560
GCAGTGTTTG TTGGGAGAAT CATCAGAGGA TACAGGCCTC ATGGATTTTC TGCTAAAGAC 1620
AAGGATGAAT CTAGAAGGCT TCTTACTTGG CCCCAAGAAG TGGATAGGAC TCAAAGGGCA 1680
GCCAAATACC TGGGGAAGAT CTTGGGAATA TGTGGGAATG TGGGAAGTGG AAAGAGCTCC 1740
CTCCTTGCAG CTCTCCTAGG ACAGATGCAG CTGCAGAAAG GGGTGGTGGC AGTCAATGGA 1800
ACTTTGGCCT ACGTTTCACA GCAGGCATGG ATCTTTCATG GAAATGTGAG AGAAAACATA 1860
CTCTTTGGAG AAAAGTATGA TCACCAAAGG TATCAGCACA CAGTCCGCGT CTGTGGCCTC 1920
CAGAAGGACC TGAGCAACCT CCCCTATGGA GACCTGACTG AGATTGGGGA GCGGGGCCTC 1980
AACCTCTCTG GGGGGCAGAG GCAGAGGATT AGCCTGGCCC GCGCTGTCTA CTCCGACCGT 2040
CAGCTCTACC TGCTGGACGA CCCCCTGTCG GCCGTGGACG CCCACGTGGG GAAGCACGTC 2100
TTTGAGGAGT GCATTAAGAA GACGCTCAGG GGAAAGACAG TCGTCCTGGT GACCCACCAG 2160
CTACAGTTCT TAGAGTCTTG TGATGAAGTT ATTTTATTAG AAGATGGAGA GATTTGTGAA 2220
AAGGGAACCC ACAAGGAGTT AATGGAGGAG AGAGGGCGCT ATGCAAAACT GATTCACAAC 2280
CTGCGAGGAT TGCAGTTCAA GGATCCTGAA CACCTTTACA ATGCAGCAAT GGTGGAAGCC 2340
TTCAAGGAGA GCCCTGCTGA GAGAGAGGAA GATGCTGGTA TAATCGGGTA CCTCCTTTCT 2400
CTCTTCACTG TGTTCCTCTT CCTCCTGATG ATTGGCAGCG CTGCCTTCAG CAACTGGTGG 2460
CTGGGTCTCT GGTTGGACAA GGGCTCACGG ATGACCTGTG GGCCCCAGGG CAACAGGACC 2520
ATGTGTGAGβ TCGGCGCGGT GCTGGCAGAC ATCGGTCAGC ATGTGTACCA GTGGGTGTAC 2580
ACTGCAAGCA TGGTGTTCAT GCTGGTGTTT GGCGTCACCA AAGGCTTCGT CTTCACCAAG 2640
ACCACACTGA TGGCATCCTC CTCTCTGCAT GACACGGTGT TTGATAAGAT CTTAAAGAGC 2700
CCAATGAGTT TCTTTGACAC GACTCCCACT GGCAGGCTAA TGAACCGTTT TTCCAAGGAT 2760
ATGGACGAGC TGGATGTGAG GCTGCCGTTT CACGCAGAGA ACTTTCTGCA GCAGTTTTTT 2820
ATGGTGGTGT TTATTCTCGT GATCTTGGCT GCTGTGTTTC CTGCTGTCCT TTTAGTCGTG 2880
GCCAGCCTTG CTGTAGGCTT CTTCATTCTG TTACGCATTT TCCACAGAGG AGTCCAGGAG 2940
CTCAAGAAGG TGGAGAATGT CAGCCGGTCA CCCTGGTTCA CCCACATCAC CTCCTCCATG 3000
CAGGGCCTGG GCATCATTCA CGCCTATGGC AAGAAGGAGA GCTGCATCAC CTATACTTCA 3060
TCCAAAGGCC TGTCATTGTC ATACATCATC CAGCTGAGCG GACTGCTCCA AGTGTGTGTG 3120
CGAACGGGAA CAGAGACGCA AGCCAAATTC ACCTCCGTGG AGCTGCTCAG GGAATACATT 3180
TCGACCTGTG TTCCTGAATG CACTCATCCC CTCAAAGTGG GGACCTGTCC CAAGGACTGG 3240
CCCAGCTGTG GGGAGATCAC CTTCAGAGAC TATCAGATGA GATACAGAGA CAACACCCCC 3300
CTTGTTCTCG ACAGCCTGAA CTTGAACATA CAAAGTGGGC AGACAGTCGG GATTGTTGGA 3360
AGAACAGGTT CCGGAAAGTC ATCGTTAGGA ATGGCTTTGT TTCGTCTGGT GGAGCCAGCC 3420
AGTGGCACAA TCTTTATTGA TGAGGTGGAT ATCTGCATTC TCAGCTTGGA AGACCTCAGA 3480
ACCAAGCTGA CTGTGATCCC ACAGGATCCT GTCCTGTTTG TAGGTACAGT AAGGTACAAC 3540
TTGGATCCCT TTGAGAGTCA CACCGATGAG ATGCTCTGGC AGGTTCTGGA GAGAACATTC 3600
ATGAGAGACA CAATAATGAA ACTCCCAGAA AAATTACAGG CAGAAGTCAC AGAAAATGGA 3660
GAAAACTTCT CAGTAGGGGA ACGTCAGCTG CTTTGTGTGG CCCGAGCTCT TCTCCGTAAT 3720
TCAAAGATCA TTCTCCTTGA TGAAGCCACC GCCTCTATGG ACTCCAAGAC TGACACCCTG 3780
GTTCAGAACA CCATCAAAGA TGCCTTCAAG GGCTGCACTG TGCTGACCAT CGCCCACCGC 3840
CTCAACACAG TTCTCAACTG CGATCACGTC CTGGTTATGG AAAATGGGAA GGTGATTGAG 3900
TTTGACAAGC CTGAAGTCCT TGCAGAGAAG CCAGATTCTG CATTTGCGAT GTTACTAGCA 3960 GCAGAAGTCA GATTGTAG
Seq ID NO : 312 Protein sequence Protein Accesεion ft : Eoε sequence 1 11 21 31 41 51
I I I I I I
MVGEGPYLIS DLDQRGRRRS FAERYDPSLK TMIPVRPCAR LAPNPVDDAG LLSFATFSWL 60
TPVMVKGYRQ RLTVDTLPPL STYDSSDTNA KRFRVLWDEE VARVGPEKAS LSHWWKFQR 120
TRVLMDIVAN ILCIIMAAIG PTVLIHQILQ QTERTSGKVW VGIGLCIALF ATEFTKVFFW 180
ALAWAINYRT AIRLKVALST LVFENLVSFK TLTHISVGEV LNILSSDSYS LFEAALFCPL 240
PATIPILMVF CAAYAFFILG PTALIGISVY VIFIPVQMFM AKLNSAFRRS AILVTDKRVQ 300
TMNEFLTCIR LIKMYAWEKS FTNTIQDIRR RERKLLEKAG FVQSGNSALA PIVSTIAIVL 360
TLSCHILLRR KLTAPVAFΞV IAMFNVMKFS IAILPFSIKA MAEANVSLRR MKKILIDKSP 420 0 PSYITQPEDP DTVLLLANAT LTWEHEASRK STPKKLQNQK RHLCKKQRSE AYSERSPPAK 480
GATGPEEQSD SLKSVLHSIS FWRKLCRYP EAQLLAWRWP AVFVGRIIRG YRPHGFSAKD 540
KDESRRLLTW PQEVDRTQRA AKYLGKILGI CGNVGSGKSS LLAALLGQMQ LQKGWAVNG 600
TLAYVSQQAW IFHGNVRENI LFGEKYDHQR YQHTVRVCGL QKDLSNLPYG DLTEIGERGL 660
NLSGGQRQRI SLARAVYSDR QLYLLDDPLS AVDAHVGKHV FEECIKKTLR GKTWLVTHQ 720 5 LQFLESCDEV ILLEDGEICE KGTHKELMEE RGRYAKLIHN LRGLQFKDPE HLYNAAMVEA 780
FKESPAEREE DAGIIGYLLS LFTVFLFLLM IGSAAFSNWW LGLWLDKGSR MTCGPQGNRT 840
MCEVGAVLAD IGQHVYQWVY TASMVFMLVF GVTKGFVFTK TTLMASSSLH DTVFDKILKS 900
PMSFFDTTPT GRLMNRFSKD MDELDVRLPF HAENFLQQFF MWFILVILA AVFPAVLLW 960
ASLAVGFFIL LRIFHRGVQE LKKVENVSRS PWFTHITSSM QGLGIIHAYG KKESCITYTS 1020 0 SKGLSLSYII QLSGLLQVCV RTGTETQAKF TSVELLREYI STCVPECTHP LKVGTCPKDW 1080
PSCGEITFRD YQMRYRDNTP LVLDSLNLNI QΞGQTVGIVG RTGSGKSSLG MALFRLVEPA 1140
SGTIFIDEVD ICILSLEDLR TKLTVIPQDP VLFVGTVRYN LDPFESHTDE MLWQVLERTF 1200
MRDTIMKLPE KLQAEVTENG ENFSVGERQL LCVARALLRN SKIILLDEAT ASMDSKTDTL 1260
VQNTIKDAFK GCTVLTIAHR LNTVLNCDHV LVMENGKVIE FDKPEVLAEK PDSAFAMLLA 1320 5 AEVRL
Seq ID NO: 313 DNA sequence Nucleic Acid Accession #: Z31560 Coding sequence: 1-966 0
1 11 21 31 41 51
C IACAGCGCCC GICATGTACAA CIATGATGGAG AICGGAGCTGA AIGCCGCCGGG CICCGCAGCAA 60
ACTTCGGGGG GCGGCGGCGG CAACTCCACC GCGGCGGCGG CCGGCGGCAA CCAGAAAAAC 120 5 AGCCCGGACC GCGTCAAGCG GCCCATGAAT GCCTTCATGG TGTGGTCCCG CGGGCAGCGG 180
CGCAAGATGG CCCAGGAGAA CCCCAAGATG CACAACTCGG AGATCAGCAA GCGCCTGGGC 240
GCCGAGTGGA AACTTTTGTC GGAGACGGAG AAGCGGCCGT TCATCGACGA GGCTAAGCGG 300
CTGCGAGCGC TGCACATGAA GGAGCACCCG GATTATAAAT ACCGGCCCCG GCGGAAAACC 360
AAGACGCTCA TGAAGAAGGA TAAGTACACG CTGCCCGGCG GGCTGCTGGC CCCCGGCGGC 420 0 AATAGCATGG CGAGCGGGGT CGGGGTGGGC GCCGGCCTGG GCGCGGGCGT GAACCAGCGC 480
ATGGACAGTT ACGCGCACAT GAACGGCTGG AGCAACGGCA GCTACAGCAT GATGCAGGAC 540
CAGCTGGGCT ACCCGCAGCA CCCGGGCCTC AATGCGCACG GCGCAGCGCA GATGCAGCCC 600
ATGCACCGCT ACGACGTGAG CGCCCTGCAG TACAACTCCA TGACCAGCTC GCAGACCTAC 660
ATGAACGGCT CGCCCACCTA CAGCATGTCC TACTCGCAGC AGGGCACCCC TGGCATGGCT 720 5 CTTGGCTCCA TGGGTTCGGT GGTCAAGTCC GAGGCCAGCT CCAGCCCCCC TGTGGTTACC 780
TCTTCCTCCC ACTCCAGGGC GCCCTGCCAG GCCGGGGACG TCCGGGACAT GATCAGCATG 840
TATCTCCCCG GCGCCGAGGT GCCGGAACCC GCCGCCCCCA GCAGACTTCA CATGTCCCAG 900
CACTACCAGA GCGGCCCGGT GCCCGGCACG GCCATTAACG GCACACTGCC CCTCTCACAC 960
ATGTGAGGGC CGGACAGCGA ACTGGAGGGG GGAGAAATTT TCAAAGAAAA ACGAGGGAAA 1020 0 TGGGAGGGGT GCAAAAGAGG AGAGTAAGAA ACAGCATGGA GAAAACCCGG TACGCTCAAA 1080 AAAAA
Seq ID NO: 314 Protein sequence Protein Accession #: CAA83435
55
1 11 21 31 41 51
I I I I I I
HSARMYNMME TELKPPGPQQ TSGGGGGNST AAAAGGNQKN SPDRVKRPMN AFMVWSRGQR 60
RKMAQENPKM HNSEISKRLG AEWKLLSETE KRPFIDEAKR LRALHMKEHP DYKYRPRRKT 120
60 KTLMKKDKYT LPGGLLAPGG NSMASGVGVG AGLGAGVNQR MDSYAHMNGW SNGSYSMMQD 180
QLGYPQHPGL NAHGAAQMQP MHRYDVSALQ YNSMTSSQTY MNGSPTYSMS YSQQGTPGMA 240
LGSMGSWKS EASSSPPWT SSSHSRAPCQ AGDLRDMISM YLPGAEVPEP AAPSRLHMSQ 300 HYQSGPVPGT AINGTLPLSH M
65 Seq ID NO: 315 DNA sequence
Nucleic Acid Accession #: U91618 Coding sequence: 29..541
„,. 1 11 21 31 41 51
70 I i i i i i
CGGACTTGGC TTGTTAGAAG GCTGAAAGAT GATGGCAGGA ATGAAAATCC AGCTTGTATG 60
CATGCTACTC CTGGCTTTCA GCTCCTGGAG TCTGTGCTCA GATTCAGAAG AGGAAATGAA 120
AGCATTAGAA GCAGATTTCT TGACCAATAT GCATACATCA AAGATTAGTA AAGCACATGT 180
TCCCTCTTGG AAGATGACTC TGCTAAATGT TTGCAGTCTT GTAAATAATT TGAACAGCCC 240
75 AGCTGAGGAA ACAGGAGAAG TTCATGAAGA GGAGCTTGTT GCAAGAAGGA AACTTCCTAC 300
TGCTTTAGAT GGCTTTAGCT TGGAAGCAAT GTTGACAATA TACCAGCTCC ACAAAATCTG 360
TCACAGCAGG GCTTTTCAAC ACTGGGAGTT AATCCAGGAA GATATTCTTG ATACTGGAAA 420
TGACAAAAAT GGAAAGGAAG AAGTCATAAA GAGAAAAATT CCTTATATTC TGAAACGGCA 480
GCTGTATGAG AATAAACCCA GAAGACCCTA CATACTCAAA AGAGATTCTT ACTATTACTG 540
80 AGAGAATAAA TCATTTATTT ACATGTGATT GTGATTCATC ATCCCTTAAT TAAATATCAA 600
ATTATATTTG TGTGAAAATG TGACAAACAC ACTTATCTGT CTCTTCTACA ATTGTGGTTT 660
ATTGAATGTG TTTTTCTGCA CTAATAGAAA TTAGACTAAG TGTTTTCAAA TAAATCTAAA 720 TCTTCAAAAA AAAAAAAAAA AAATGGGGCC GCAATT Seq ID NO: 316 Protein sequence Protein Accession ft : AAB50564
1 11 21 31 41 51
I I I I I I
MMAGMKIQLV CMLLLAFSSW SLCSDSEEEM KALEADFLTN MHTSKISKAH VPSWKMTLLN 60 VCSLVNNLNS PAEETGEVHE EELVARRKLP TALDGFSLEA MLTIYQLHKI CHSRAFQHWE 120 LIQEDILDTG NDKNGKEEVI KRKIPYILKR QLYENKPRRP YILKRDSYYY
Seq ID NO: 317 DNA sequence
Nucleic Acid Accession ft: NM_006536.2
Coding sequence: 109..2940
1 11 21 31 41 51
I I I I I I
ACCTAAAACC TTGCAAGTTC AGGAAGAAAC CATCTGCATC CATATTGAAA ACCTGACACA 60
ATGTATGCAG CAGGCTCAGT GTGAGTGAAC TGGAGGCTTC TCTACAACAT GACCCAAAGG 120
AGCATTGCAG GTCCTATTTG CAACCTGAAG TTTGTGACTC TCCTGGTTGC CTTAAGTTCA 180
GAACTCCCAT TCCTGGGAGC TGGAGTACAG CTTCAAGACA ATGGGTATAA TGGATTGCTC 240
ATTGCAATTA ATCCTCAGGT ACCTGAGAAT CAGAACCTCA TCTCAAACAT TAAGGAAATG 300
ATAACTGAAG CTTCATTTTA CCTATTTAAT GCTACCAAGA GAAGAGTATT TTTCAGAAAT 360
ATAAAGATTT TAATACCTGC CACATGGAAA GCTAATAATA ACAGCAAAAT AAAACAAGAA 420
TCATATGAAA AGGCAAATGT CATAGTGACT GACTGGTATG GGGCACATGG AGATGATCCA 480
TACACCCTAC AATACAGAGG GTGTGGAAAA GAGGGAAAAT ACATTCATTT CACACCTAAT 540
TTCCTACTGA ATGATAACTT AACAGCTGGC TACGGATCAC GAGGCCβAGT GTTTGTCCAT 600
GAATGGGCCC ACCTCCGTTG GGGTGTGTTC GATGAGTATA ACAATGACAA ACCTTTCTAC 660
ATAAATGGGC AAAATCAAAT TAAAGTGACA AGGTGTTCAT CTGACATCAC AGGCATTTTT 720
GTGTGTGAAA AAGGTCCTTG CCCCCAAGAA AACTGTATTA TTAGTAAGCT TTTTAAAGAA 780
GGATGCACCT TTATCTACAA TAGCACCCAA AATGCAACTG CATCAATAAT GTTCATGCAA 840
AGTTTATCTT CTGTGGTTGA ATTTTGTAAT GCAAGTACCC ACAACCAAGA AGCACCAAAC 900
CTACAGAACC AGATGTGCAG CCTCAGAAGT GCATGGGATG TAATCACAGA CTCTGCTGAC 960
TTTCACCACA GCTTTCCCAT GAATGGGACT GAGCTTCCAC CTCCTCCCAC ATTCTCGCTT 1020
GTACAGGCTG GTGACAAAGT GGTCTGTTTA GTGCTGGATG TGTCCAGCAA GATGGCAGAG 1080
GCTGACAGAC TCCTTCAACT ACAACAAGCC GCAGAATTTT ATTTGATGCA GATTGTTGAA 1140
ATTCATACCT TCGTGGGCAT TGCCAGTTTC GACAGCAAAG GAGAGATCAG AGCCCAGCTA 1200
CACCAAATTA ACAGCAATGA TGATCGAAAG TTGCTGGTTT CATATCTGCC CACCACTGTA 1260
TCAGCTAAAA CAGACATCAG CATTTGTTCA GGGCTTAAGA AAGGATTTGA GGTGGTTGAA 1320
AAACTGAATG GAAAAGCTTA TGGCTCTGTG ATGATATTAG TGACCAGCGG AGATGATAAG 1380
CTTCTTGGCA ATTGCTTACC CACTGTGCTC AGCAGTGGTT CAACAATTCA CTCCATTGCC 1440
CTGGGTTCAT CTGCAGCCCC AAATCTGGAG GAATTATCAC GTCTTACAGG AGGTTTAAAG 1500
TTCTTTGTTC CAGATATATC AAACTCCAAT AGCATGATTG ATGCTTTCAG TAGAATTTCC 1560
TCTGGAACTG GAGACATTTT CCAGCAACAT ATTCAGCTTG AAAGTACAGG TGAAAATGTC 1620
AAACCTCACC ATGAATTGAA AAACACAGTG ACTGTGGATA ATACTGTGGG CAACGACACT 1680
ATGTTTCTAG TTACGTGGCA GGCCAGTGGT CCTCCTGAGA TTATATTATT TGATCCTGAT 1740
GGACGAAAAT ACTACACAAA TAATTTTATC ACCAATCTAA CTTTTCGGAC AGCTAGTCTT 1800
TGGATTCCAβ GAACAGCTAA GCCTGGGCAC TGGACTTACA CCCTGAACAA TACCCATCAT 1860
TCTCTGCAAG CCCTGAAAGT GACAGTGACC TCTCGCGCCT CCAACTCAGC TGTGCCCCCA 1920
GCCACTGTGβ AAGCCTTTGT GGAAAGAGAC AGCCTCCATT TTCCTCATCC TGTGATGATT 1980
TATGCCAATG TGAAACAGGG ATTTTATCCC ATTCTTAATG CCACTGTCAC TGCCACAGTT 2040
GAGCCAGAGA CTGGAGATCC TGTTACGCTG AGACTCCTTG ATGATGGAGC AGGTGCTGAT 2100
GTTATAAAAA ATGATGGAAT TTACTCGAGG TATTTTTTCT CCTTTGCTGC AAATGGTAGA 2160
TATAGCTTGA AAGTGCATGT CAATCACTCT CCCAGCATAA GCACCCCAGC CCACTCTATT 2220
CCAGGGAGTC ATGCTATGTA TGTACCAGGT TACACAGCAA ACGGTAATAT TCAGATGAAT 2280
GCTCCAAGGA AATCAGTAGG CAGAAATGAG GAGGAGCGAA AGTGGGGCTT TAGCCGAGTC 2340
AGCTCAGGAG GCTCCTTTTC AGTGCTGGGA GTTCCAGCTG GCCCCCACCC TGATGTGTTT 2400
CCACCATGCA AAATTATTGA CCTGGAAGCT GTAAAAGTAG AAGAGGAATT GACCCTATCT 2460
TGGACAGCAC CTGGAGAAGA CTTTGATCAG GGCCAGGCTA CAAGCTATGA AATAAGAATG 2520
AGTAAAAGTC TACAGAATAT CCAAGATGAC TTTAACAATG CTATTTTAGT AAATACATCA 2580
AAGCGAAATC CTCAGCAAGC TGGCATCAGG GAGATATTTA CGTTCTCACC CCAGATTTCC 2640
ACGAATGGAC CTGAACATCA GCCAAATGGA GAAACACATG AAAGCCACAG AATTTATGTT 2700
GCAATACGAG CAATGGATAG GAACTCCTTA CAGTCTGCTG TATCTAACAT TGCCCAGGCG 2760
CCTCTGTTTA TTCCCCCCAA TTCTGATCCT GTACCTGCCA GAGATTATCT TATATTGAAA 2820
GGAGTTTTAA CAGCAATGGG TTTGATAGGA ATCATTTGCC TTATTATAGT TGTGACACAT 2880
CATACTTTAA GCAGGAAAAA GAGAGCAGAC AAGAAAGAGA ATGGAACAAA ATTATTATAA 2940
ATAAATATCC AAAGTGTCTT CCTTCTTAGA TATAAGACCC ATGGCCTTCG ACTACAAAAA 3000
CATACTAACA AAGTCAAATT AACATCAAAA CTGTATTAAA ATGCATTGAG TTTTTGTACA 3060
ATACAGATAA GATTTTTACA TGGTAGATCA ACAATTCTTT TTGGGGGTAG ATTAGAAAAC 3120
CCTTACACTT TGGCTATGAA CAAATAATAA AAATTATTCT TTAAAGTAAT GTCTTTAAAG 3180
GCAAAGGGAA GGGTAAAGTC GGACCAGTGT CAAGGAAAGT TTGTTTTATT GAGGTGGAAA 3240
AATAGCCCCA AGCAGAGAAA AGGAGGGTAG GTCTGCATTA TAACTGTCTG TGTGAAGCAA 3300
TCATTTAGTT ACTTTGATTA ATTTTTCTTT TCTCCTTATC TGTGCAGTAC AGGTTGCTTG 3360
TTTACATGAA GATCATGCTA TATTTTATAT ATGTAGCCCC TAATGCAAAG CTCTTTACCT 3420
CTTGCTATTT TGTTATATAT ATTTCAGATG ACATCTCCCT GCTAATGCTC AGAGATCTTT 3480
TTTCACTGTA AGAGGTAACC TTTAACAATA TGGGTATTAC CTTTGTCTCT TCATACCGGT 3540
TTTATGACAA AGGTCTATTG AATTTATTTG TNTGTAAGTT TCTACTCCCA TCAAAGCAGC 3600
TTTCTAAGTT TATTGCCTTG GGTTATTATG GAATGATAGT TATAGCCCCN TATAATGCCT 3660 TACCTAGGAA A
Seq ID NO: 318 Protein sequence Protein Accession #: NP 006527.1
1 11 21 31 41 51
I I I I I I
MTQRSIAGPI CNLKFVTLLV ALSSELPFLG AGVQLQDNGY NGLLIAINPQ VPENQNLISN IKEMITEASF YLFNATKRRV FFRNIKILIP ATWKANNNSK IKQESYEKAN VIVTDWYGAH 120 GDDPYTLQYR GCGKEGKYIH FTPNFLLNDN LTAGYGSRGR VFVHEWAHLR WGVFDEYNND 180 KPFYINGQNQ IKVTRCSSDI TGIFVCEKGP CPQENCIISK LFKEGCTFI NSTQNATASI 240 MFMQSLSSW EFCNASTHNQ EAPNLQNQMC SLRSAWDVIT DSADFHHSFP MNGTELPPPP 300 TFSLVQAGDK WCLVLDVSS KMAEADRLLQ LQQAAEFYLM QIVEIHTFVG IASFDSKGEI 360 RAQLHQINSN DDRKLLVSYL PTTVSAKTDI SICSGLKKGF EWEKLNGKA YGSVMILVTS 420 GDDKLLGNCL PTVLSSGSTI HSIALGSSAA PNLEELSRLT GGLKFFVPDI SNSNSMIDAF 480 SRISSGTGDI FQQHIQLEST GENVKPHHQL KNTVTVDNTV GNDTMFLVTW QASGPPEIIL 540 FDPDGRKYYT NNFITNLTFR TASLWIPGTA KPGHWTYTLN NTHHSLQALK VTVTSRASNS 600 AVPPATVEAF VERDSLHFPH PVMIYANVKQ GFYPILNATV TATVEPETGD PVTLRLLDDG 660 AGADVIKNDG IYSRYFFSFA ANGRYSLKVH VNHSPSISTP AHSIPGSHAM YVPGYTANGN 720 IQMNAPRKSV GRNEEERKWG FSRVSSGGSF SVLGVPAGPH PDVFPPCKII DLEAVKVEEE 780 LTLSWTAPGE DFDQGQATSY EIRMSKSLQN IQDDFNNAIL VNTSKRNPQQ AGIREIFTFS 840 PQISTNGPEH QPNGETHESH RIYVAIRAMD RNSLQSAVSN IAQAPLFIPP NSDPVPARDY 900 LILKGVLTAM GLIGIICLII WTHHTLSRK KRADKKENGT KLL
Seq ID NO: 319 DNA sequence
Nucleic Acid Accession ft: NM_000228.1
Coding sequence: 82..3600
1 11 21 31 41 51
I I I I I I
GCTTTCAGGC GATCTGGAGA AAGAACGGCA GAACACACAG CAAGGAAAGG TCCTTTCTGG 60
GGATCACCCC ATTGGCTGAA GATGAGACCA TTCTTCCTCT TGTGTTTTGC CCTGCCTGGC 120
CTCCTGCATG CCCAACAAGC CTGCTCCCGT GGGGCCTGCT ATCCACCTGT TGGGGACCTG 180
CTTGTTGGGA GGACCCGGTT TCTCCGAGCT TCATCTACCT GTGGACTGAC CAAGCCTGAG 240
ACCTACTGCA CCCAGTATGG CGAGTGGCAG ATGAAATGCT GCAAGTGTGA CTCCAGGCAG 300
CCTCACAACT ACTACAGTCA CCGAGTAGAG AATGTGGCTT CATCCTCCGG CCCCATGCGC 360
TGGTGGCAGT CCCAGAATGA TGTGAACCCT GTCTCTCTGC AGCTGGACCT GGACAGGAGA 420
TTCCAGCTTC AAGAAGTCAT GATGGAGTTC CAGGGGCCCA TGCCCGCCGG CATGCTGATT 480
GAGCGCTCCT CAGACTTCGG TAAGACCTGG CGAGTGTACC AGTACCTGGC TGCCGACTGC 540
ACCTCCACCT TCCCTCGGGT CCGCCAGGGT CGGCCTCAGA GCTGGCAGGA TGTTCGGTGC 600
CAGTCCCTGC CTCAGAβGCC TAATGCACGC CTAAATGGGG GGAAGGTCCA ACTTAACCTT 660
ATGGATTTAβ TGTCTGGGAT TCCAGCAACT CAAAGTCAAA AAATTCAAGA GGTGGGGGAG 720
ATCACAAACT TGAGAGTCAA TTTCACCAGG CTGGCCCCTG TGCCCCAAAG GGGCTACCAC 780
CCTCCCAGCG CCTACTATGC TGTGTCCCAG CTCCGTCTGC AGGGGAGCTG CTTCTGTCAC 840
GGCCATGCTG ATCGCTGCGC ACCCAAGCCT GGGGCCTCTG CAGGCCCCTC CACCGCTGTG 900
CAGGTCCACG ATGTCTGTGT CTGCCAGCAC AACACTGCCG GCCCAAATTG TGAGCGCTGT 960
GCACCCTTCT ACAACAACCG GCCCTGGAGA CCGGCGGAGG GCCAGGACGC CCATGAATGC 1020
CAAAGGTGCG ACTGCAATGG GCACTCAGAG ACATGTCACT TTGACCCCGC TGTGTTTGCC 1080
GCCAGCCAGG GGGCATATGG AGGTGTGTGT GACAATTGCC GGGACCACAC CGAAGGCAAG 1140
AACTGTGAGC GGTGTCAGCT GCACTATTTC CGGAACCGGC GCCCGGGAGC TTCCATTCAG 1200
GAGACCTGCA TCTCCTGCGA GTGTGATCCG GATGGGGCAG TGCCAGGGGC TCCCTGTGAC 1260
CCAGTGACCG GGCAGTGTGT GTGCAAGGAG CATGTGCAGG GAGAGCGCTG TGACCTATGC 1320
AAGCCGGGCT TCACTGGACT CACCTACGCC AACCCGCAOJG GCTGCCACCG CTGTGACTGC 1380
AACATCCTGG GGTCCCGGAG GGACATGCCG TGTGACGAGG AGAGTGGGCG CTGCCTTTGT 1440
CTGCCCAACG TGGTGGGTCC CAAATGTGAC CAGTGTGCTC CCTACCACTG GAAGCTGGCC 1500
AGTGGCCAGG GCTGTGAACC GTGTGCCTGC GACCCGCACA ACTCCCCTCA GCCCACAGTG 1560
CAACCAGTTC ACAGGGCAGT GCCCTGTCGG GAAGGCTTTG GTGGCCTGAT GTGCAGCGCT 1620
GCAGCCATCC GCCAGTGTCC AGACCGGACC TATGGAGACG TGGCCACAGG ATGCCGAGCC 1680
TGTGACTGTG ATTTCCGGGG AACAGAGGGC CCGGGCTGCG ACAAGGCATC AGGCCGCTGC 1740
CTCTGCCGCC CTGGCTTGAC CGGGCCCCGC TGTGACCAGT GCCAGCGAGG CTACTGCAAT 1800
CGCTACCCGG TGTGCGTGGC CTGCCACCCT TGCTTCCAGA CCTATGATGC GGACCTCCGG 1860
GAGCAGGCCC TGCGCTTTGG TAGACTCCGC AATGCCACCG CCAGCCTGTG GTCAGGGCCT 1920
GGGCTGGAGG ACCGTGGCCT GGCCTCCCGG ATCCTAGATG CAAAGAGTAA GATTGAGCAG 1980
ATCCGAGCAG TTCTCAGCAG CCCCGCAGTC ACAGAGCAGG AGGTGGCTCA GGTGGCCAGT 2040
GCCATCCTCT CCCTCAGGCG AACTCTCCAG GGCCTGCAGC TGGATCTGCC CCTGGAGGAG 2100
GAGACGTTGT CCCTTCCGAG AGACCTGGAG AGTCTTGACA GAAGCTTCAA TGGTCTCCTT 2160
ACTATGTATC AGAGGAAGAG GGAGCAGTTT GAAAAAATAA GCAGTGCTGA TCCTTCAGGA 2220
GCCTTCCGGA TGCTGAGCAC AGCCTACGAG CAGTCAGCCC AGGCTGCTCA GCAGGTCTCC 2280
GACAGCTCGC GCCTTTTGGA CCAGCTCAGG GACAGCCGGA GAGAGGCAGA GAGGCTGGTG 2340
CGGCAGGCGG GAGGAGGAGG AGGCACCGGC AGCCCCAAGC TTGTGGCCCT GAGGCTGGAG 2400
ATGTCTTCGT TGCCTGACCT GACACCCACC TTCAACAAGC TCTGTGGCAA CTCCAGGCAG 2460
ATGGCTTGCA CCCCAATATC ATGCCCTGGT GAGCTATGTC CCCAAGACAA TGGCACAGCC 2520
TGTGGCTCCC GCTGCAGGGG TGTCCTTCCC AGGGCCGGTG GGGCCTTCTT GATGGCGGGG 2580
CAGGTGGCTG AGCAGCTGCG GGGCTTCAAT GCCCAGCTCC AGCGGACCAG GCAGATGATT 2640
AGGGCAGCCG AGGAATCTGC CTCACAGATT CAATCCAGTG CCCAGCGCTT GGAGACCCAG 2700
GTGAGCGCCA GCCGCTCCCA GATGGAGGAA GATGTCAGAC GCACACGGCT CCTAATCCAG 2760
CAGGTCCGGG ACTTCCTAAC AGACCCCGAC ACTGATGCAG CCACTATCCA GGAGGTCAGC 2820
GAGGCCGTGC TGGCCCTGTG GCTGCGCACA GACTCAGCTA CTGTTCTGCA GAAGATGAAT 2880
GAGATCCAGG CCATTGCAGC CAGGCTCCCC AACGTGGACT TGGTGCTGTC CCAGACCAAG 2940
CAGGACATTG CGCGTGCCCG CCGGTTGCAG GCTGAGGCTG AGGAAGCCAG GAGCCGAGCC 3000
CATGCAGTGG AGGGCCAGGT GGAAGATGTG GTTGGGAACC TGCGGCAGGG GACAGTGGCA 3060
CTGCAGGAAG CTCAGGACAC CATGCAAGGC ACCAGCCGCT CCCTTCGGCT TATCCAGGAC 3120
AGGGTTGCTG AGGTTCAGCA GGTACTGCGG CCAGCAGAAA AGCTGGTGAC AAGCATGACC 3180
AAGCAGCTGG GTGACTTCTG GACACGGATG GAGGAGCTCC GCCACCAAGC CCGGCAGCAG 3240
GGGGCAGAGG CAGTCCAGGC CCAGCAGCTT GCGGAAGGTG CCAGCGAGCA GGCATTGAGT 3300
GCCCAAGAGG GATTTGAGAG AATAAAACAA AAGTATGCTG AGTTGAAGGA CCGGTTGGGT 3360
CAGAGTTCCA TGCTGGGTGA GCAGGCTGCC CGGATCCAGA GTGTGAAGAC AGAGGCAGAG 3420
GAGCTGTTTG GGGAGACCAT GGAGATGATG GACAGGATGA AAGACATGGA GTTGGAGCTG 3480
CTGCGGGGCA GCCAGGCCAT CATGCTGCGC TCGGCGGACC TGACAGGACT GGAGAAGCGT 3540
GTGGAGCAGA TCCGTGACCA CATCAATGGG CGCGTGCTCT ACTATGCCAC CTGCAAGTGA 3600
TGCTACAGCT TCCAGCCCGT TGCCCCACTC ATCTGCCGCC TTTGCTTTTG GTTGGGGGCA 3660
GATTGGGTTG GAATGCTTTC CATCTCCAGG AGACTTTCAT GCAGCCTAAA GTACAGCCTG 3720 GACCACCCCT GGTGTGTAGC TAGTAAGATT ACCCTGAGCT GCAGCTGAGC CTGAGCCAAT 3780
GGGACAGTTA CACTTGACAG ACAAAGATGG TGGAGATTGG CATGCCATTG AAACTAAGAG 3840
CTCTCAAGTC AAGGAAGCTG GGCTGGGCAG TATCCCCCGC CTTTAGTTCT CCACTGGGGA 3900
GGAATCCTGG ACCAAGCACA AAAACTTAAC AAAAGTGATG TAAAAATGAA AAGCCAAATA 3960 AAAATCTTTG G
Seq ID NO: 320 Protein sequence Protein Accesεion tf: NP 000219.1
11 21 31 41 51
I I I I I
MRPFFLLCFA LPGLLHAQQA CSRGACYPPV GDLLVGRTRF LRASSTCGLT KPETYCTQYG 60 EWQMKCCKCD SRQPHNYYSH RVENVASSSG PMRWWQSQND VNPVSLQLDL DRRFQLQEVM 120 MEFQGPMPAG MLIERSSDFG KTWRVYQYLA ADCTSTFPRV RQGRPQSWQD VRCQSLPQRP 180 NARLNGGKVQ LNLMDLVΞGI PATQSQKIQE VGEITNLRVN FTRLAPVPQR GYHPPSAYYA 240 VSQLRLQGSC FCHGHADRCA PKPGASAGPS TAVQVHDVCV CQHNTAGPNC ERCAPFYNNR 300 PWRPAEGQDA HECQRCDCNG HSETCHFDPA VFAASQGAYG GVCDNCRDHT EGKNCERCQL 360 HYFRNRRPGA SIQETCISCE CDPDGAVPGA PCDPVTGQCV CKEHVQGERC DLCKPGFTGL 420 TYANPQGCHR CDCNILGSRR DMPCDEESGR CLCLPNWGP KCDQCAPYHW KLASGQGCEP 480 CACDPHNSPQ PTVQPVHRAV PCREGFGGLM CSAAAIRQCP DRTYGDVATG CRACDCDFRG 540 TEGPGCDKAS GRCLCRPGLT GPRCDQCQRG YCNRYPVCVA CHPCFQTYDA DLREQALRFG 600 RLRNATASLW SGPGLEDRGL ASRILDAKSK lEQIRAVLSS PAVTEQEVAQ VASAILSLRR 660 TLQGLQLDLP LEEETLSLPR DLESLDRSFN GLLTMYQRKR EQFEKISSAD PSGAFRMLST 720 AYEQSAQAAQ QVSDSSRLLD QLRDSRREAE RLVRQAGGGG GTGSPKLVAL RLEMSSLPDL 780 TPTFNKLCGN SRQMACTPIS CPGELCPQDN GTACGSRCRG VLPRAGGAFL MAGQVAEQLR 840 GFNAQLQRTR QMIRAAEESA SQIQSSAQRL ETQVSASRSQ MEEDVRRTRL LIQQVRDFLT 900 DPDTDAATIQ EVSEAVLALW LPTDSATVLQ KMNEIQAIAA RLPNVDLVLS QTKQDIARAR 960 RLQAEAEEAR SRAHAVEGQV ED GNLRQG TVALQEAQDT MQGTSRSLRL IQDRVAEVQQ 1020 VLRPAEKLVT SMTKQLGDFW TRMEELRHQA RQQGAEAVQA QQLAEGASEQ ALSAQEGFER 1080 IKQKYAELKD RLGQSSMLGE QGARIQSVKT EAEELFGETM EMMDRMKDME LELLRGSQAI 1140 MLRSADLTGL EKRVEQIRDH INGRVLYYAT CK
Seq ID NO: 321 DNA sequence Nucleic Acid Accession ft: NM_001944.1 Coding sequence: 84..3083
11 21 31 41 51
TTTTCTTAGA CATTAACTGC AGACGGCTGG CAGGATAGAA GCAGCGGCTC ACTTGGACTT 60
TTTCACCAGG GAAATCAGAG ACAATGATGG GGCTCTTCCC CAGAACTACA GGGGCTCTGG 120
CCATCTTCGT GGTGGTCATA TTGGTTCATG GAGAATTGCG AATAGAGACT AAAGGTCAAT 180
ATGATGAAGA AGAGATGACT ATGCAACAAG CTAAAAGAAG GCAAAAACGT GAATGGGTGA 240
AATTTGCCAA ACCCTGCAGA GAAGGAGAAG ATAACTCAAA AAGAAACCCA ATTGCCAAGA 300
TTACTTCAGA TTACCAAGCA ACCCAGAAAA TCACCTACCG AATCTCTGGA GTGGGAATCG 360
ATCAGCCGCC TTTTGGAATC TTTGTTGTTG ACAAAAACAC TGGAGATATT AACATAACAG 420
CTATAGTCGA CCGGGAGGAA ACTCCAAGCT TCCTGATCAC ATGTCGGGCT CTAAATGCCC 480
AAGGACTAGA TGTAGAGAAA CCACTTATAC TAACGGTTAA AATTTTGGAT ATTAATGATA 540
ATCCTCCAGT ATTTTCACAA CAAATTTTCA TGGGTGAAAT TGAAGAAAAT AGTGCCTCAA 600
ACTCACTGGT GATGATACTA AATGCCACAG ATGCAGATGA ACCAAACCAC TTGAATTCTA 660
AAATTGCCTT CAAAATTGTC TCTCAGGAAC CAGCAGGCAC ACCCATGTTC CTCCTAAGCA 720
GAAACACTGG GGAAGTCCGT ACTTTGACCA ATTCTCTTGA CCGAGAGCAA GCTAGCAGCT 780
ATCGTCTGGT TGTGAGTGGT GCAGACAAAG ATGGAGAAGG ACTATCAACT CAATGTGAAT 840
GTAATATTAA AGTGAAAGAT GTCAACGATA ACTTCCCAAT GTTTAGAGAC TCTCAGTATT 900
CAGCACGTAT TGAAGAAAAT ATTTTAAGTT CTGAATTACT TCGATTTCAA GTAACAGATT 960
TGGATGAAGA GTACACAGAT AATTGGCTTG CAGTATATTT CTTTACCTCT GGGAATGAAG 1020
GAAATTGGTT TGAAATACAA ACTGATCCTA GAACTAATGA AGGCATCCTG AAAGTGGTGA 1080
AGGCTCTAGA TTATGAACAA CTACAAAGCG TGAAACTTAG TATTGCTGTC AAAAACAAAG 1140
CTGAATTTCA CCAATCAGTT ATCTCTCGAT ACCGAGTTCA GTCAACCCCA GTCACAATTC 1200
AGGTAATAAA TGTAAGAGAA GGAATTGCAT TCCGTCCTGC TTCCAAGACA TTTACTGTGC 1260
AAAAAGGCAT AAGTAβCAAA AAATTGGTGG ATTATATCCT GGGAACATAT CAAGCCATCG 1320
ATGAGGACAC TAACAAAGCT GCCTCAAATG TCAAATATGT CATGGGACGT AACGATGGTG 1380
GATACCTAAT GATTGATTCA AAAACTGCTG AAATCAAATT TGTCAAAAAT ATGAACCGAG 1440
ATTCTACTTT CATAGTTAAC AAAACAATCA CAGCTGAGGT TCTGGCCATA GATGAATACA 1500
CGGGTAAAAC TTCTACAGGC ACGGTATATG TTAGAGTACC CGATTTCAAT GACAATTGTC 1560
CAACAGCTGT CCTCGAAAAA GATGCAGTTT GCAGTTCTTC ACCTTCCGTG GTTGTCTCCG 1620
CTAGAACACT GAATAATAGA TACACTGGCC CCTATACATT TGCACTGGAA GATCAACCTG 1680
TAAAGTTGCC TGCCGTATGG AGTATCACAA CCCTCAATGC TACCTCGGCC CTCCTCAGAG 1740
CCCAGGAACA GATACCTCCT GGAGTATACC ACATCTCCCT GGTACTTACA GACAGTCAGA 1800
ACAATCGGTG TGAGATGCCA CGCAGCTTGA CACTGGAAGT CTGTCAGTGT GACAACAGGG 1860
GCATCTGTGG AACTTCTTAC CCAACCACAA GCCCTGGGAC CAGGTATGGC AGGCCGCACT 1920
CAGGGAGGCT GGGGCCTGCC GCCATCGGCC TGCTGCTCCT TGGTCTCCTG CTGCTGCTGT 1980
TGGCCCCCCT TCTGCTGTTG ACCTGTGACT GTGGGGCAGG TTCTACTGGG GGAGTGACAG 2040
GTGGTTTTAT CCCAGTTCCT GATGGCTCAG AAGGAACAAT TCATCAGTGG GGAATTGAAG 2100
GAGCCCATCC TGAAGACAAG GAAATCACAA ATATTTGTGT GCCTCCTGTA ACAGCCAATG 2160
GAGCCGATTT CATGGAAAGT TCTGAAGTTT GTACAAATAC GTATGCCAGA GGCACAGCGG 2220
TGGAAGGCAC TTCAGGAATG GAAATGACCA CTAAGCTTGG AGCAGCCACT GAATCTGGAG 2280
GTGCTGCAGG CTTTGCAACA GGGACAGTGT CAGGAGCTGC TTCAGGATTC GGAGCAGCCA 2340
CTGGAGTTGG CATCTGTTCC TCAGGGCAGT CTGGAACCAT GAGAACAAGG CATTCCACTG 2400
GAGGAACCAA TAAGGACTAC GCTGATGGGG CGATAAGCAT GAATTTTCTG GACTCCTACT 2460
TTTCTCAGAA AGCATTTGCC TGTGCGGAGG AAGACGATGG CCAGGAAGCA AATGACTGCT 2520
TGTTGATCTA TGATAATGAA GGCGCAGATG CCACTGGTTC TCCTGTGGGC TCCGTGGGTT 2580
GTTGCAGTTT TATTGCTGAT GACCTGGATG ACAGCTTCTT GGACTCACTT GGACCCAAAT 2640
TTAAAAAACT TGCAGAGATA AGCCTTGGTG TTGATGGTGA AGGCAAAGAA GTTCAGCCAC 2700
CCTCTAAAGA CAGCGGTTAT GGGATTGAAT CCTGTGGCCA TCCCATAGAA GTCCAGCAGA 2760 CAGGATTTGT TAAGTGCCAG ACTTTGTCAG GAAGTCAAGG AGCTTCTGCT TTGTCCGCCT 2820 CTGGGTCTGT CCAGCCAGCT GTTTCCATCC CTGACCCTCT GCAGCATGGT AACTATTTAG 2880 TAACGGAGAC TTACTCGGCT TCTGGTTCCC TCGTGCAACC TTCCACTGCA GGCTTTGATC 2940 CACTTCTCAC ACAAAATGTG ATAGTGACAG AAAGGGTGAT CTGTCCCATT TCCAGTGTTC 3000 CTGGCAACCT AGCTGGCCCA ACGCAGCTAC GAGGGTCACA TACTATGCTC TGTACAGAGG 3060 ATCCTTGCTC CCGTCTAATA TGACCAGAAT GAGCTGGAAT ACCACACTGA CCAAATCTGG 3120 ATCTTTGGAC TAAAGTATTC AAAATAGCAT AGCAAAGCTC ACTGTATTGG GCTAATAATT 3180 TGGCACTTAT TAGCTTCTCT CATAAACTGA TCACGATTAT AAATTAAATG TTTGGGTTCA 3240 TACCCCAAAA GCAATATGTT GTCACTCCTA ATTCTCAAGT ACTATTCAAA TTGTAGTAAA 3300 TCTTAAAGTT TTTCAAAACC CTAAAATCAT ATTCGC
Seq ID NO: 322 Protein sequence Protein Accession ft: NP 001935.1
11 21 31 41 51
I I I I I
MMGLFPRTTG ALAIFV IL VHGELRIETK GQYDEEEMTM QQAKRRQKRE WVKFAKPCRE 60 GEDNSKRNPI AKITSDYQAT QKITYRISGV GIDQPPFGIF WDKNTGDIN ITAIVDREET 120 PSFLITCRAL NAQGLDVEKP LILTVKILDI NDNPPVFSQQ IFMGEIEENS ASNSLVMILN 180 ATDADEPNHL NSKIAFKIVS QEPAGTPMFL LSRNTGEVRT LTNSLDREQA SSYRLWSGA 240 DKDGEGLSTQ CECNIKVKDV NDNFPMFRDS QYSARIEENI LSSELLRFQV TDLDEEYTDN 300 WLAVYFFTSG NEGNWFEIQT DPRTNEGILK WKALDYEQL QSVKLSIAVK NKAEFHQSVI 360 SRYRVQSTPV TIQVINVREG IAFRPASKTF TVQKGIΞSKK LVDYILGTYQ AIDEDTNKAA 420 SNVKYVMGRN DGGYLMIDSK TAEIKFVKNM NRDSTFIVNK TITAEVLAID EYTGKTSTGT 480 VYVRVPDFND NCPTAVLEKD AVCSSSPSW VSARTLNNRY TGPYTFALED QPVKLPAVWS 540 ITTLNATSAL LRAQEQIPPG VYHISLVLTD SQNNRCEMPR SLTLEVCQCD NRGICGTSYP 600 TTSPGTRYGR PHSGRLGPAA IGLLLLGLLL LLLAPLLLLT CDCGAGΞTGG VTGGFIPVPD 660 GSEGTIHQWG IEGAHPEDKE ITNICVPPVT ANGADFMESS EVCTNTYARG TAVEGTSGME 720 MTTKLGAATE SGGAAGFATG TVSGAASGFG AATGVGICSS GQSGTMRTRH STGGTNKDYA 780 DGAISMNFLD SYFSQKAFAC AEEDDGQEAN DCLLIYDNEG ADATGSPVGS VGCCSFIADD 840 LDDSFLDSLG PKFKKLAEIS LGVDGEGKEV QPPSKDSGYG IESCGHPIEV QQTGFVKCQT 900 LSGSQGASAL SASGSVQPAV SIPDPLQHGN YLVTETYSAS GSLVQPSTAβ FDPLLTQNVI 960 VTERVICPIS SVPGNLAGPT QLRGSHTMLC TEDPCSRLI
Seq ID NO: 323 DNA sequence
Nucleic Acid Accesεion ft: XM_058069.2
Coding sequence : 1..1413
11 21 31 41 51
I I I I
ATGAAGTTTC TTCTAATACT GCTCCTGCAG GCCACTGCTT CTGGAGCTCT TCCCCTGAAC 60 AGCTCTACAA GCCTGGAAAA AAATAATGTG CTATTTGGTG AAAGATACTT AGAAAAATTT 120 TATGGCCTTG AGATAAACAA ACTTCCAGTG ACAAAAATGA AATATAGTGG AAACTTAATG 180 AAGGAAAAAA TCCAAGAAAT GCAGCACTTC TTGGGTCTGA AAGTGACCGG GCAACTGGAC 240 ACATCTACCC TGGAGATGAT GCACGCACCT CGATGTGGAG TCCCCGATGT CCATCATTTC 300 AGGGAAATGC CAGGGGGGCC CGTATGGAGG AAACATTATA TCACCTACAG AATCAATAAT 360 TACACACCTG ACATGAACCG TGAGGATGTT GACTACGCAA TCCGGAAAGC TTTCCAAGTA 420 TGGAGTAATG TTACCCCCTT GAAATTCAGC AAGATTAACA CAGGCATGGC TGACATTTTG 480 GTGGTTTTTG CCCGTGGAGC TCATGGAGAC TTCCATGCTT TTGATGGCAA AGGTGGAATC 540 CTAGCCCATG CTTTTGGACC TGGATCTGGC ATTGGAGGGG ATGCACATTT CGATGAGGAC 600 GAATTCTGGA CTACACATTC AGGAGGCACA AACTTGTTCC TCACTGCTGT TCACGAGATT 660 GGCCATTCCT TAGGTCTTGG CCATTCTAGT GATCCAAAGG CCGTAATGTT CCCCACCTAC 720 AAATATGTTG ACATCAACAC ATTTCGCCTC TCTGCTGATG ACATACGTGG CATTCAGTCC 780 CTGTATGGAG ACCCAAAAGA GAACCAACGC TTGCCAAATC CTGACAATTC AGAACCAGCT 840 CTCTGTGACC CCAATTTGAG TTTTGATGCT GTCACTACCG TGGGAAATAA GATCTTTTTC 900 TTCAAAGACA GGTTCTTCTG GCTGAAGGTT TCTGAGAGAC CAAAGACCAG TGTTAATTTA 960 ATTTCTTCCT TATGGCCAAC CTTGCCATCT GGCATTGAAG CTGCTTATGA AATTGAAGCC 1020 AGAAATCAAG TTTTTCTTTT TAAAGATGAC AAATACTGGT TAATTAGCAA TTTAAGACCA 1080 GAGCCAAATT ATCCCAAGAG CATACATTCT TTTGGTTTTC CTAACTTTGT GAAAAAAATT 1140 GATGCAGCTG TTTTTAACCC ACGTTTTTAT AGGACCTACT TCTTTGTAGA TAACCAGTAT 1200 TGGAGGTATG ATGAAAGGAG ACAGATGATG GACCCTGGTT ATCCCAAACT GATTACCAAG 1260 AACTTCCAAG GAATCGGGCC TAAAATTGAT GCAGTCTTCT ACTCTAAAAA CAAATACTAC 1320 TATTTCTTCC AAGGATCTAA CCAATTTGAA TATGACTTCC TACTCCAACG TATCACCAAA 1380 ACACTGAAAA GCAATAGCTG GTTTGGTTGT TGA
Seq ID NO: 324 Protein sequence Protein Accession if: P39900
11 21 31 41 51
I I I I I I
MKFLLILLLQ ATASGALPLN SSTSLEKNNV LFGERYLEKF YGLEINKLPV TKMKYSGNLM 60 KEKIQEMQHF LGLKVTGQLD TSTLEMMHAP RCGVPDVHHF REMPGGPVWR KHYITYRINN 120 YTPDMNREDV DYAIRKAFQV WSNVTPLKFS KINTGMADIL WFARGAHGD FHAFDGKGGI 180 LAHAFGPGSG IGGDAHFDED EFWTTHSGGT NLFLTAVHEI GHSLGLGHSS DPKAVMFPTY 240 KYVDINTFRL SADDIRGIQS LYGDPKENQR LPNPDNSEPA LCDPNLSFDA VTTVGNKIFF 300 FKDRFFWLKV SERPKTSVNL ISSLWPTLPS GIEAAYEIEA RNQVFLFKDD KYWLISNLRP 360 EPNYPKΞIHS FGFPNFVKKI DAAVFNPRFY RTYFFVDNQY WRYDERRQMM DPGYPKLITK 420 NFQGIGPKID AVFYSKNKYY YFFQGSNQFE YDFLLQRITK TLKSNSWFGC
Seq ID NO: 325 DNA sequence
Nucleic Acid Accession ft: NM_024423.1
Coding sequence: 64..2590
11 21 31 51 I I I I I I
GGCAGGTCTC GCTCTCGGCA CCCTCCCGGC GCCCGCGTTC TCCTGGCCCT GCCCGGCATC 60
CCGATGGCCG CCGCTGGGCC CCGGCGCTCC GTGCGCGGAG CCGTCTGCCT GCATCTGCTG 120
CTGACCCTCG TGATCTTCAG TCGTGATGGT GAAGCCTGCA AAAAGGTGAT ACTTAATGTA 180
CCTTCTAAAC TAGAGGCAGA CAAAATAATT GGCAGAGTTA ATTTGGAAGA GTGCTTCAGG 240
TCTGCAGACC TCATCCGGTC AAGTGATCCT GATTTCAGAG TTCTAAATGA TGGGTCAGTG 300
TACACAGCCA GGGCTGTTGC GCTGTCTGAT AAGAAAAGAT CATTTACCAT ATGGCTTTCT 360
GACAAAAGGA AACAGACACA GAAAGAGGTT ACTGTGCTGC TAGAACATCA GAAGAAGGTA 420
TCGAAGACAA GACACACTAG AGAAACTGTT CTCAGGCGTG CCAAGAGGAG ATGGGCACCT 480
ATTCCTTGCT CTATGCAAGA GAATTCCTTG GGCCCTTTCC CATTGTTTCT TCAACAAGTT 540
GAATCTGATG CAGCACAGAA CTATACTGTC TTCTACTCAA TAAGTGGACG TGGAGTTGAT 600
AAAGAACCTT TAAATTTGTT TTATATAGAA AGAGACACTG GAAATCTATT TTGCACTCGG 660
CCTGTGGATC GTGAAGAATA TGATGTTTTT GATTTGATTG CTTATGCGTC AACTGCAGAT 720
GGATATTCAG CAGATCTGCC CCTCCCACTA CCCATCAGGG TAGAGGATGA AAATGACAAC 780
CACCCTGTTT TCACAGAAGC AATTTATAAT TTTGAAGTTT TGGAAAGTAG TAGACCTGGT 840
ACTACAGTGG GGGTGGTTTG TGCCACAGAC AGAGATGAAC CGGACACAAT GCATACGCGC 900
CTGAAATACA GCATTTTGCA GCAGACACCA AGGTCACCTG GGCTCTTTTC TGTGCATCCC 960
AGCACAGGCG TAATCACCAC AGTCTCTCAT TATTTGGACA GAGAGGTTGT AGACAAGTAC 1020
TCATTGATAA TGAAAGTACA AGACATGGAT GGCCAGTTTT TTGGATTGAT AGGCACATCA 1080
ACTTGTATCA TAACAGTAAC AGATTCAAAT GATAATGCAC CCACTTTCAG ACAAAATGCT 1140
TATGAAGCAT TTGTAGAGGA AAATGCATTC AATGTGGAAA TCTTACGAAT ACCTATAGAA 1200
GATAAGGATT TAATTAACAC TGCCAATTGG AGAGTCAATT TTACCATTTT AAAGβGAAAT 1260
GAAAATGGAC ATTTCAAAAT CAGCACAGAC AAAGAAACTA ATGAAGGTGT TCTTTCTGTT 1320
GTAAAGCCAC TGAATTATGA AGAAAACCGT CAAGTGAACC TGGAAATTGG AGTAAACAAT 1380
GAAGCGCCAT TTGCTAGAGA TATTCCCAGA GTGACAGCCT TGAACAGAGC CTTGGTTACA 1440
GTTCATGTGA GGGATCTGGA TGAGGGGCCT GAATGCACTC CTGCAGCCCA ATATGTGCGG 1500
ATTAAAGAAA ACTTAGCAGT GGGGTCAAAG ATCAACGGCT ATAAGGCATA TGACCCCGAA 1560
AATAGAAATG GCAATGGTTT AAGGTACAAA AAATTGCATG ATCCTAAAGG TTGGATCACC 1620
ATTGATGAAA TTTCAGGGTC AATCATAACT TGCAAAATCC TGGATAGGGA GGTTGAAACT 1680
CCCAAAAATG AGTTGTATAA TATTACAGTC CTGGCAATAG ACAAAGATGA TAGATCATGT 1740
ACTGGAACAC TTGCTGTGAA CATTGAAGAT GTAAATGATA ATCCACCAGA AATACTTCAA 1800
GAATATGTAG TCATTTGCAA ACCAAAAATG GGGTATACCG ACATTTTAGC TGTTGATCCT 1860
GATGAACCTG TCCATGGAGC TCCATTTTAT TTCAGTTTGC CCAATACTTC TCCAGAAATC 1920
AGTAGACTGT GGAGCCTCAC CAAAGTTAAT GATACAGCTG CCCGTCTTTC ATATCAGAAA 1980
AATGCTGGAT TTCAAGAATA TACCATTCCT ATTACTGTAA AAGACAGGGC CGGCCAAGCT 2040
GCAACAAAAT TATTGAGAGT TAATCTGTGT GAATGTACTC ATCCAACTCA GTGTCGTGCG 2100
ACTTCAAGGA GTACAGGAGT AATACTTGGA AAATGGGCAA TCCTTGCAAT ATTACTGGGT 2160
ATAGCACTGC TCTTTTCTGT ATTGCTAACT TTAGTATGTG GAGTTTTTGG TGCAACTAAA 2220
GGGAAACGTT TTCCTGAAGA TTTAGCACAG CAAAACTTAA TTATATCAAA CACAGAAGCA 2280
CCTGGAGACG ATAGAGTGTG CTCTGCCAAT GGATTTATGA CCCAAACTAC CAACAACTCT 2340
AGCCAAGGTT TTTGTGGTAC TATGGGATCA GGAATGAAAA ATGGAGGGCA GGAAACCATT 2400
GAAATGATGA AAGGAGGAAA CCAGACCTTG GAATCCTGCC GGGGGGCTGG GCATCATCAT 2460
ACCCTGGACT CCTGCAGGGG AGGACACACG GAGGTGGACA ACTGCAGATA CACTTACTCG 2520
GAGTGGCACA GTTTTACTCA ACCCCGTCTC GGTGAAGAAT CCATTAGAGG ACACACTGGT 2580
TAAAAATTAA ACATAAAAGA AATTGCATCG ATGTAATCAG AATGAAGACC GCATGCCATC 2640
CCAAGATTAT GTCCTCACTT ATAACTATGA GGGAAGAGGA TCTCCAGCTG GTTCTGTGGG 2700
CTGCTGCAGT GAAAAGCAGG AAGAAGATGG CCTTGACTTT TTAAATAATT TGGAACCCAA 2760
ATTTATTACA TTAGCAGAAG CATGCACAAA GAGATAATGT CACAGTGCTA CAATTAGGTC 2820
TTTGTCAGAC ATTCTGGAGG TTTCCAAAAA TAATATTGTA AAGTTCAATT TCAACATGTA 2880
TGTATATGAT GATTTTTTTC TCAATTTTGA ATTATGCTAC TCACCAATTT ATATTTTTAA 2940
AGCCAGTTGT TGCTTATCTT TTCCAAAAAG TGAAAAATGT TAAAACAGAC AACTGGTAAA 3000
TCTCAAACTC CAGCACTGGA ATTAAGGTCT CTAAAGCATC TGCTCTTTTT TTTTTTTACG 3060
GATATTTTAG TAATAAATAT GCTGGATAAA TATTAGTCCA ACAATAGCTA AGTTATGCTA 3120
ATATCACATT ATTATGTATT CACTTTAAGT GATAGTTTAA AAAATAAACA AGAAATATTG 3180
AGTATCACTA TGTGAAGAAA GTTTTGGAAA AGAAACAATG AAGACTGAAT TAAATTAAAA 3240
ATGTTGCAGC TCATAAAGAA TTGGGACTCA CCCCTACTGC ACTACCAAAT TCATTTGACT 3300
TTGGAGGCAA AATGTGTTGA AGTGCCCTAT GAAGTAGCAA TTTTCTATAG GAATATAGTT 3360
GGAAATAAAT GTGTGTGTGT ATATTATTAT TAATCAATGC AATATTTAAA ATGAAATGAG 3420
AACAAAGAGG AAAATGGTAA AAACTTGAAA TGAGGCTGGG GTATAGTTTG TCCTACAATA 3480
GAAAAAAGAG AGAGCTTCCT AGGCCTGGGC TCTTAAATGC TGCATTATAA CTGAGTCTAT 3540
GAGGAAATAG TTCCTCTCCA ATTTGTGTAA TTTGTTTAAA ATTGTAAATA AATTAAACTT 3600
TTCTGGTTTC TGTGGGAAGG AAATAGGGAA TCCAATGGAA CAGTAGCTTT GCTTTGCAGT 3660
CTGTTTCAAG ATTTCTGCAT CCACAAGTTA GTAGCAAACT GGGGAATACT CGCTGCAGCT 3720
GGGGTTCCCT GCTTTTTGGT AGCAAGGGTC CAGAGATGAG GTGTTTTTTT CGGGGAGCTA 3780
ATAACAAAAA CATTTTAAAA CTTACCTTTA CTGAAGTTAA ATCCTCTATT GCTGTTTCTA 3840
TTCTCTCTTA TAGTGACCAA CATCTTTTTA ATTTAGATCC AAATAACCAT GTCCTCCTAG 3900
AGTTTAGAGG CTAGAGGGAG CTGAGGGGAG GATCTTACTG AAAGCACCCT GGGGAGATTG 3960
ATTGTCCTTA AACCTAAGCC CCACAAACTT GACACCTGAT CAGGTCTGGG AGCTACAAAA 4020
TTTCATTTTT CTCCTCACTG CCCTTCTTCT GAGTGGCATT GGCCTGAATC AAGGAAAGCC 4080
AGGCCTTGTG GGCCCCCTTC TTTCGGCTTT CTGCTAAAGC AACACCTCCA GCAGAGATTC 4140
CCTTAAGTGA CTCCAGGTTT TCCACCATCC TTCAGCGTGA ATTAATTTTT AATCAGTTTG 4200
CTTTCTCCAG AGAAATTTTA AAATAATAGA AGAAATAGAA ATTTTGAATG TATAAAAGAA 4260
AAAGATCAAG TTGTCATTTT AGAACAGAGG GAACTTTGGG AGAAAGCAGC CCAAGTAGGT 4320
TATTTGTACA GTCAGAGGGC AACAGGAAGA TGCAGGCCTT CAAGGGCAAG GAGAGGCCAC 4380
AAGGAATATG GGTGGGAGTA AAAGCAACAT CGTCTGCTTC ATACTTTTTC CTAGGCTTGG 4440
CACTGCCTTT TCCTTTCTCA GGCCAATGGC AACTGCCATT TGAGTCCGGT GAGGGATCAG 4500
CCAACCTCTT CTCTATGGCT CACCTTATTT GGAGTGAGAA ATCAAGGAGA CAGAGCTGAC 4560
TGCATGATGA GTCTGAAGGC ATTTGCAGGA TGAGCCTGAA CTGGTTGTGC AGAACAAACA 4620
AGGCATTCAT GGGAATTβTT GTATTCCTTC TGCAGCCCTC CTTCTGGGCA CTAAGAAGGT 4680
CTATGAATTA AATGCCTATC TAAAATTCTG ATTTATTCCT ACATTTTCTG TTTTCTAATT 4740
TGACCCTAAA ATCTATGTGT TTTAGACTTA GACTTTTTAT TGCCCCCCCC CCCTTTTTTT 4800
TTGAGACGGA GTCTCGCTCT GACGCACAGG CTGGAGTGCA GTGGCTCCGA TCTCTGCTCA 4860
CTGAAAGCTC CGCCTCCCGG GTTCATGCCA TTCTCCTGCC TCAGCCTCCT GAGTAGCTGG 4920
GACTACAGGC GCCCACCACC ACGCCCGGCT AATTTTTTGT ATTTTTAATA GAGACGGGGT 4980 TTCACTGTGT TAGCCAGGAT GGTCTCGATC TCCTGACCTC GTGATCCGCC TGCCTCGGCC 5040 TCCCAAAGTG CTGGGATTAC AGGCATGACC CACCGCTCCC GGCCTTGTTT TCCGTTTAAA 5100 GTCGTCTTCT TTTAATGTAA TCATTTTGAA CATGTGTGAA AGTTGATCAT ACGAATTGGA 5160 TCAATCTTGA AATACTCAAC CAAAAGACAG TCGAGAAGCC AGGGGGAGAA AGAACTCAGG 5220 GCACAAAATA TTGGTCTGAG AATGGAATTC TCTGTAAGCC TAGTTGCTGA AATTTCCTGC 5280 TGTAACCAGA AGCCAGTTTT ATCTAACGGC TACTGAAACA CCCACTGTGT TTTGCTCACT 5340 CCCACTCACC GATCAAAACC TGCTACCTCC CCAAGACTTT ACTAGTGCCG ATAAACTTTC 5400 TCAAAGAGCA ACCAGTATCA CTTCCCTGTT TATAAAACCT CTAACCATCT CTTTGTTCTT 5460 TGAACATGCT GAAAACCACC TGGTCTGCAT GTATGCCCGA ATTTGTAATT CTTTTCTCTC 5520 AAATGAAAAT TTAATTTTAG GGATTCATTT CTATATTTTC AGATATGTAG TATTATTATT 5580 TCCTTATATG TGTAAGGTGA AATTTATGGT ATTTGAGTGT GCAAGAAAAT ATATTTTTAA 5640 AGCTTTCATT TTTCCCCCAG TGAATGATTT AGAATTTTTT ATGTAAATAT ACAGAATGTT 5700 TTTTCTTACT TTTATAAGGA AGCAGCTGTC TAAAATGCAG TGGGGTTTGT TTTGCAATGT 5760 TTTAAACAGA GTTTTAGTAT TGCTATTAAA AGAAGTTACT TTGCTTTTAA AGAAACTTGG 5820 CTGCTTAAAA TAAGCAAAAA TTGGATGCAT AAAGTAATAT TTACAGATGT GGGGAGATGT 5880 AATAAAACAA TATTAACTTG GCTGCTTAAA ATAAGCAAAA ATTGGATGCA TAAAGTAATA 5940 TTTACAGATβ TGGGGAGATG TAATAAAACA ATATTAACTT GGTTTCTTGT TTTTGCTGTA 6000 TTTAGAGATT AAATAATTCT AAGATGATCA CTTTGCAAAA TTATGCTTAT GGCTGGCATG 6060 GAAATAGAAA TACTCAATTA TGTCTTTGTT GTATTAATGG GGAATATTTT GGACAATGTT 6120 TCATTATCAA ATTGTCGACA TCATTAATAT ATATTGTAAT GTTGGGAAGA GATCACTATT 6180 TTGAAGCACA GCTTTACAGA TGAGTATCTA TGATACATAT GTATAATAAA TTTTGATCGG 6240 GTATTAAAAβ TATTAGAAGG TGGTTATAAT TGCAGAGTAT TCCATGAATA GTACACTGAC 6300 ACAGGGGTTT TACTTTGAGG ACCAGTGTAG TCAAGGGAAA ACATGAGTTA AAAAGAAAAG 6360 CAGGCAATAT TGCAGTCTTG ATTCTGCCAC TTACAGGATA GATAATGCCT GAACTTTAAT 6420 GACAAGATGA TCCAACCATA AAGGTGCTCT GTGCTTCACA GTGAATCTTT TCCCCATGCA 6480 GGAGTGTGCT CCCCTACAAA CGTTAAGACT GATCATTTCA AAAATCTATT AGCTATATCA 6540 AAAGCCTTAC ATTTTAATAT AGGTTGAACC AAAATTTCAA TTCCAGTAAC TTCTATTGTA 6600 ACCATTATTT TTGTGTATGT CTTCAAGAAT GTTCATTGGA TTTTTGTTTG TAATAGTAAA 6660 ATACCGGATA CATTTCACGT GTCCTTCAGT ATTGATTTGG TTGAATATTG GGTCATAATG 6720 GTTGAGAAGC ATGGACACTA GAGCCAGAAT GCTTGGATAT GAATCCTGGA TCTGTCACTT 6780 ACTTCTCTGT GACCTTTGAA AGGCTACTTA TTTCCTCTCT TAGCTTTCTC ATTAAAATCA 6840 ATGAACAATG CCAGCCTCAT GGGGTTGTTG AATGATTAAA TTAGTTAATA TACCTAAAGT 6900 ACATAGAACA CTGCCTGCAC ATAGTAAAAG AATTATAAGT GTGAGGTAGT TGGTAAAATT 6960 ATGTAGTTGG ATATACTACC GAACAATATC TAATCTCTTT TTAGGGAAAT AAAGTTTGTG 7020 CATATATATA ATCCCGAAAC ATG
Seq ID NO: 326 Protein sequence Protein Accession ft: NP 077741.1
11 21 31 51
MAAAGPRRSV RGAVCLHLLL TLVIFSRDGE ACKKVILNVP SKLEADKIIG RVNLEECFRS 60
ADLIRSSDPD FRVLNDGSVY TARAVALSDK KRSFTIWLSD KRKQTQKEVT VLLEHQKKVS 120
KTRHTRETVL RRAKRRWAPI PCSMQENSLG PFPLFLQQVE SDAAQNYTVF YSISGRGVDK 180
EPLNLFYIER DTGNLFCTRP VDREEYDVFD LIAYASTADG YSADLPLPLP IRVEDENDNH 240
PVFTEAIYNF EVLESSRPGT TVGWCATDR DEPDTMHTRL KYSILQQTPR SPGLFSVHPS 300
TGVITTVSHY LDREWDKYS LIMKVQDMDG QFFGLIGTST CIITVTDSND NAPTFRQNAY 360
EAFVEENAFN VEILRIPIED KDLINTANWR VNFTILKGNE NGHFKISTDK ETNEGVLSW 420
KPLNYEENRQ VNLEIGVNNE APFARDIPRV TALNRALVTV HVRDLDEGPE CTPAAQYVRI 480
KENLAVGSKI NGYKAYDPEN RNGNGLRYKK LHDPKGWITI DEISGSIITS KILDREVETP 540
KNELYNITVL AIDKDDRSCT GTLAVNIEDV NDNPPEILQE YWICKPKMG YTDILAVDPD 600
EPVHGAPFYF SLPNTSPEIS RLWSLTKVND TAARLSYQKN AGFQEYTIPI TVKDRAGQAA 660
TKLLRVNLCE CTHPTQCRAT SRSTGVILGK WAILAILLGI ALLFSVLLTL VCGVFGATKG 720
KRFPEDLAQQ NLIISNTEAP GDDRVCSANβ FMTQTTNNSS QGFCGTMGSG MKNGGQETIE 780
MMKGGNQTLE SCRGAGHHHT LDSCRGGHTE VDNCRYTYSE WHSFTQPRLG EESIRGHTG
Seq ID NO: 327 DNA sequence
Nucleic Acid Accession ft: NM_001941.2
Coding sequence: 64..2754
1 11 21 31 41 51
1 1 | 1 | 1 1 1 1 GGCAGGTCTC GCTCTCGGCA CCCTCCCGGC GCCCGCGTTC TCCTGGCCCT GCCCGGCATC 60
CCGATGGCCG CCGCTGGGCC CCGGCGCTCC GTGCGCGGAβ CCGTCTGCCT GCATCTGCTG 120
CTGACCCTCG TGATCTTCAG TCGTGATGGT GAAGCCTGCA AAAAGGTGAT ACTTAATGTA 180
CCTTCTAAAC TAGAGGCAGA CAAAATAATT GGCAGAGTTA ATTTGGAAGA GTGCTTCAGG 240
TCTGCAGACC TCATCCGGTC AAGTGATCCT GATTTCAGAG TTCTAAATGA TGGGTCAGTG 300
TACACAGCCA GGGCTGTTGC GCTGTCTGAT AAGAAAAGAT CATTTACCAT ATGGCTTTCT 360
GACAAAAGGA AACAGACACA GAAAGAGGTT ACTGTGCTGC TAGAACATCA GAAGAAGGTA 420
TCGAAGACAA GACACACTAG AGAAACTGTT CTCAGGCGTG CCAAGAGGAG ATGGGCACCT 480
ATTCCTTGCT CTATGCAAGA GAATTCCTTG GGCCCTTTCC CATTGTTTCT TCAACAAGTT 540
GAATCTGATG CAGCACAGAA CTATACTGTC TTCTACTCAA TAAGTGGACG TGGAGTTGAT 600
AAAGAACCTT TAAATTTGTT TTATATAGAA AGAGACACTG GAAATCTATT TTGCACTCGG 660
CCTGTGGATC GTGAAGAATA TGATGTTTTT GATTTGATTG CTTATGCGTC AACTGCAGAT 720
GGATATTCAG CAGATCTGCC CCTCCCACTA CCCATCAGGG TAGAGGATGA AAATGACAAC 780
CACCCTGTTT TCACAGAAGC AATTTATAAT TTTGAAGTTT TGGAAAGTAG TAGACCTGGT 840
ACTACAGTGG GGGTGGTTTG TGCCACAGAC AGAGATGAAC CGGACACAAT GCATACGCGC 900
CTGAAATACA GCATTTTGCA GCAGACACCA AGGTCACCTG GGCTCTTTTC TGTGCATCCC 960
AGCACAGGCG TAATCACCAC AGTCTCTCAT TATTTGGACA GAGAGGTTGT AGACAAGTAC 1020
TCATTGATAA TGAAAGTACA AGACATGGAT GGCCAGTTTT TTGGATTGAT AGGCACATCA 1080
ACTTGTATCA TAACAGTAAC AGATTCAAAT GATAATGCAC CCACTTTCAG ACAAAATGCT 1140
TATGAAGCAT TTGTAGAGGA AAATGCATTC AATGTGGAAA TCTTACGAAT ACCTATAGAA 1200
GATAAGGATT TAATTAACAC TGCCAATTGG AGAGTCAATT TTACCATTTT AAAGGGAAAT 1260
GAAAATGGAC ATTTCAAAAT CAGCACAGAC AAAGAAACTA ATGAAGGTGT TCTTTCTGTT 1320 GTAAAGCCAC TGAATTATGA AGAAAACCGT CAAGTGAACC TGGAAATTGG AGTAAACAAT 1380 GAAGCGCCAT TTGCTAGAGA TATTCCCAGA GTGACAGCCT TGAACAGAGC CTTGGTTACA 1440 GTTCATGTGA GGGATCTGGA TGAGGGGCCT GAATGCACTC CTGCAGCCCA ATATGTGCGG 1500 ATTAAAGAAA ACTTAGCAGT GGGGTCAAAG ATCAACGGCT ATAAGGCATA TGACCCCGAA 1560 AATAGAAATG GCAATGGTTT AAGGTACAAA AAATTGCATG ATCCTAAAGG TTGGATCACC 1620 ATTGATGAAA TTTCAGGGTC AATCATAACT TCCAAAATCC TGGATAGGGA GGTTGAAACT 1680 CCCAAAAATG AGTTGTATAA TATTACAGTC CTGGCAATAG ACAAAGATGA TAGATCATGT 1740 ACTGGAACAC TTGCTGTGAA CATTGAAGAT GTAAATGATA ATCCACCAGA AATACTTCAA 1800 GAATATGTAG TCATTTGCAA ACCAAAAATG GGGTATACCG ACATTTTAGC TGTTGATCCT 1860 GATGAACCTG TCCATGGAGC TCCATTTTAT TTCAGTTTGC CCAATACTTC TCCAGAAATC 1920 AGTAGACTGT GGAGCCTCAC CAAAGTTAAT GATACAGCTG CCCGTCTTTC ATATCAGAAA 1980 AATGCTGGAT TTCAAGAATA TACCATTCCT ATTACTGTAA AAGACAGGGC CGGCCAAGCT 2040 GCAACAAAAT TATTGAGAGT TAATCTGTGT GAATGTACTC ATCCAACTCA GTGTCGTGCG 2100 ACTTCAAGGA GTACAGGAGT AATACTTGGA AAATGGGCAA TCCTTGCAAT ATTACTGGGT 2160 ATAGCACTGC TCTTTTCTGT ATTGCTAACT TTAGTATGTG GAGTTTTTGG TGCAACTAAA 2220 GGGAAACGTT TTCCTGAAGA TTTAGCACAG CAAAACTTAA TTATATCAAA CACAGAAGCA 2280 CCTGGAGACG ATAGAGTGTG CTCTGCCAAT GGATTTATGA CCCAAACTAC CAACAACTCT 2340 AGCCAAGGTT TTTGTGGTAC TATGGGATCA GGAATGAAAA ATGGAGGGCA GGAAACCATT 2400 GAAATGATGA AAGGAGGAAA CCAGACCTTG GAATCCTGCC GGGGGGCTGG GCATCATCAT 2460 ACCCTGGACT CCTGCAGGGG AGGACACACG GAGGTGGACA ACTGCAGATA CACTTACTCG 2520 GAGTGGCACA GTTTTACTCA ACCCCGTCTC GGTGAAAAAT TGCATCGATG TAATCAGAAT 2580 GAAGACCGCA TGCCATCCCA AGATTATGTC CTCACTTATA ACTATGAGGG AAGAGGATCT 2640 CCAGCTGGTT CTGTGGGCTG CTGCAGTGAA AAGCAGGAAG AAGATGGCCT TGACTTTTTA 2700 AATAATTTGG AACCCAAATT TATTACATTA GCAGAAGCAT GCACAAAGAG ATAATGTCAC 2760 AGTGCTACAA TTAGGTCTTT GTCAGACATT CTGGAGGTTT CCAAAAATAA TATTGTAAAG 2820 TTCAATTTCA ACATGTATGT ATATGATGAT TTTTTTCTCA ATTTTGAATT ATGCTACTCA 2880 CCAATTTATA TTTTTAAAGC CAGTTGTTGC TTATCTTTTC CAAAAAGTGA AAAATGTTAA 2940 AACAGACAAC TGGTAAATCT CAAACTCCAG CACTGGAATT AAGGTCTCTA AAGCATCTGC 3000 TCTTTTTTTT TTTTACGGAT ATTTTAGTAA TAAATATGCT GGATAAATAT TAGTCCAACA 3060 ATAGCTAAGT TATGCTAATA TCACATTATT ATGTATTCAC TTTAAGTGAT AGTTTAAAAA 3120 ATAAACAAGA AATATTGAGT ATCACTATGT GAAGAAAGTT TTGGAAAAGA AACAATGAAG 3180 ACTGAATTAA ATTAAAAATG TTGCAGCTCA TAAAGAATTG GGACTCACCC CTACTGCACT 3240 ACCAAATTCA TTTGACTTTG GAGGCAAAAT GTGTTGAAGT GCCCTATGAA 'GTAGCAATTT 3300 TCTATAGGAA TATAGTTGGA AATAAATGTG TGTGTGTATA TTATTATTAA TCAATGCAAT 3360 ATTTAAAATG AAATGAGAAC AAAGAGGAAA ATGGTAAAAA CTTGAAATGA GGCTGGGGTA 3420 TAGTTTGTCC TACAATAGAA AAAAGAGAGA GCTTCCTAGG CCTGGGCTCT TAAATGCTGC 3480 ATTATAACTG AGTCTATGAG GAAATAGTTC CTGTCCAATT TGTGTAATTT GTTTAAAATT 3540 GTAAATAAAT TAAACTTTTC TGGTTTCTGT GGGAAGGAAA TAGGGAATCC AATGGAACAG 3600 TAGCTTTGCT TTGCAGTCTG TTTCAAGATT TCTGCATCCA CAAGTTAGTA GCAAACTGGG 3660 GAATACTCGC TGCAGCTGGG GTTCCCTGCT TTTTGGTAGC AAGGGTCCAG AGATGAGGTG 3720 TTTTTTTCGG GGAGCTAATA ACAAAAACAT TTTAAAACTT ACCTTTACTG AAGTTAAATC 3780 CTCTATTGCT GTTTCTATTC TCTCTTATAG TGACCAACAT CTTTTTAATT TAGATCCAAA 3840 TAACCATGTC CTCCTAGAGT TTAGAGGCTA GAGGGAGCTG AGGGGAGGAT CTTACTGAAA 3900 GCACCCTGGG GAGATTGATT GTCCTTAAAC CTAAGCCCCA CAAACTTGAC ACCTGATCAG 3960 GTCTGGGAGC TACAAAATTT CATTTTTCTC CTCACTGCCC TTCTTCTGAG TGGCATTGGC 4020 CTGAATCAAG GAAAGCCAGG CCTTGTGGGC CCCCTTCTTT CGGCTTTCTG CTAAAGCAAC 4080 ACCTCCAGCA GAGATTCCCT TAAGTGACTC CAGGTTTTCC ACCATCCTTC AGCGTGAATT 4140 AATTTTTAAT CAGTTTGCTT TCTCCAGAGA AATTTTAAAA TAATAGAAGA AATAGAAATT 4200 TTGAATGTAT AAAAGAAAAA GATCAAGTTG TCATTTTAGA ACAGAGGGAA CTTTGGGAGA 4260 AAGCAGCCCA AGTAGGTTAT TTGTACAGTC AGAGGGCAAC AGGAAGATGC AGGCCTTCAA 4320 GGGCAAGGAG AGGCCACAAG GAATATGGGT GGGAGTAAAA GCAACATCGT CTGCTTCATA 4380 CTTTTTCCTA GGCTTGGCAC TGCCTTTTCC TTTCTCAGGC CAATGGCAAC TGCCATTTGA 4440 GTCCGGTGAG GGATCAGCCA ACCTCTTCTC TATGGCTCAC CTTATTTGGA GTGAGAAATC 4500 AAGGAGACAG AGCTGACTGC ATGATGAGTC TGAAGGCATT TGCAGGATGA GCCTGAACTG 4560 GTTGTGCAGA ACAAACAAGG CATTCATGGG AATTGTTGTA TTCCTTCTGC AGCCCTCCTT 4620 CTGGGCACTA AGAAGGTCTA TGAATTAAAT GCCTATCTAA AATTCTGATT TATTCCTACA 4680 TTTTCTGTTT TCTAATTTGA CCCTAAAATC TATGTGTTTT AGACTTAGAC TTTTTATTGC 4740 CCCCCCCCCC TTTTTTTTTG AGACGGAGTC TCGCTCTGAC GCACAGGCTG GAGTGCAGTG 4800 GCTCCGATCT CTGCTCACTG AAAGCTCCGC CTCCCGGGTT CATGCCATTC TCCTGGCTCA 4860 GCCTCCTGAG TAGCTGGGAC TACAGGCGCC CACCACCACG CCCGGCTAAT TTTTTGTATT 4920 TTTAATAGAG ACGGGGTTTC ACTGTGTTAG CCAGGATGGT CTCGATCTCC TGACCTCGTG 4980 ATCCGCCTGC CTCGGCCTCC CAAAGTGCTO GGATTACAGG CATGACCCAC CGCTCCCGGC 5040 CTTGTTTTCC GTTTAAAGTC GTCTTCTTTT AATGTAATCA TTTTGAACAT GTGTGAAAGT 5100 TGATCATACG AATTGGATCA ATCTTGAAAT AGTCAAGCAA AAGACAGTCG AGAAGCCAGG 5160 GGGAGAAAGA ACTCAGGGCA CAAAATATTβ GTCTGAGAAT GGAATTCTCT GTAAGCCTAG 5220 TTGCTGAAAT TTCCTGCTGT AACCAGAAGC CAGTTTTATC TAACGGCTAC TGAAACACCC 5280 ACTGTGTTTT GCTCACTCCC TCACTCACCG ATCAAAACCT GCTACCTCCC CAAGACTTTA 5340 CTAGTGCCGA TAAACTTTCT CAAAGAGCAA CCAGTATCAC TTCCCTGTTT ATAAAACCTC 5400 TAACCATCTC TTTGTTCTTT GAACATGCTG AAAACCACCT GGTCTGCATG TATGCCCGAA 5460 TTTGTAATTC TTTTCTCTCA AATGAAAATT TAATTTTAGG GATTCATTTC TATATTTTCA 5520 CATATGTAGT ATTATTATTT CCTTATATGT GTAAGGTGAA ATTTATGGTA TTTGAGTGTG 5580 CAAGAAAATA TATTTTTAAA GCTTTCATTT TTCCCCCAGT GAATGATTTA GAATTTTTTA 5640 TGTAAATATA CAGAATGTTT TTTCTTACTT TTATAAGGAA GCAGCTGTCT AAAATGCAGT 5700 GGGGTTTGTT TTGCAATGTT TTAAACAGAG TTTTAGTATT GCTATTAAAA GAAGTTACTT 5760 TGCTTTTAAA GAAACTTGGC TGCTTAAAAT AAGCAAAAAT TGGATGCATA AAGTAATATT 5820 TACAGATGTG GGGAGATGTA ATAAAACAAT ATTAACTTGG TTTCTTGTTT TTGCTGTATT 5880 TAGAGATTAA ATAATTCTAA GATGATCACT TTGCAAAATT ATGCTTATGG CTGGCATGGA 5940 AATAGAAATA CTCAATTATG TCTTTGTTGT ATTAATGGGG AATATTTTGG ACAATGTTTC 6000 ATTATCAAAT TGTCGACATC ATTAATATAT ATTGTAATGT TGGGAAGAGA TCACTATTTT 6060 GAAGCACAGC TTTACAGATG AGTATCTATG ATACATATGT ATAATAAATT TTGATCGGGT 6120 ATTAAAAGTA TTAGAAGGTG GTTATAATTG CAGAGTATTC CATGAATAGT ACACTGACAC 6180 AGGGGTTTTA CTTTGAGGAG CAGTGTAGTC AAGGGAAAAC ATGAGTTAAA AAGAAAAGCA 6240 GGCAATATTG CAGTCTTGAT TCTGCCACTT ACAGGATAGA TAATGCCTGA ACTTTAATGA 6300 CAAGATGATC CAACCATAAA GGTGCTCTGT GCTTCACAGT GAATCTTTTC CCCATGCAGG 6360 AGTGTGCTCC CCTACAAACG TTAAGACTGA TCATTTCAAA AATCTATTAG CTATATCAAA 6420 AGCCTTACAT TTTAATATAG GTTGAACCAA AATTTCAATT CCAGTAACTT CTATTGTAAC 6480 CATTATTTTT GTGTATGTCT TCAAGAATGT TCATTGGATT TTTGTTTGTA ATAGTAAAAT 6540 ACCGGATACA TTTCACGTGT CCTTCAGTAT TGATTTGGTT GAATATTGGG TCATAATGGT 6600 TGAGAAGCAT GGACACTAGA GCCAGAATGC TTGGATATGA ATCCTGGATC TGTCACTTAC 6660 TTCTGTGTGA CCTTTGAAAG GCTACTTATT TCCTCTCTTA GCTTTCTCAT TAAAATCAAT 6720 GAACAATGCC AGCCTCATGG GGTTGTTGAA TGATTAAATT AGTTAATATA CCTAAAGTAC 6780 ATAGAACACT GCCTGCACAT AGTAAAAGAA TTATAAGTGT GAGGTAGTTG GTAAAATTAT 6840 GTAGTTGGAT ATACTACCGA ACAATATCTA ATCTCTTTTT AGGGAAATAA AGTTTGTGCA 6900 TATATATAAT CCCGAAACAT G
Seq ID NO: 328 Protein sequence Protein Accession ft: NP 001932.1
1 11 21 31 41 51 1 1 1 1 | 1 | 1 | 1 I 1 MAAAGPRRSV RGAVCLHLLL TLVIFSRDGE ACKKVILNVP SKLEADKIIG RVNLEECFRS 60
ADLIRSSDPD FRVLNDGSVY TARAVALSDK KRΞFTIWLSD KRKQTQKEVT VLLEHQKKVS 120
KTRHTRETVL RRAKRRWAPI PCSMQENSLG PFPLFLQQVE SDAAQNYTVF YSISGRGVDK 180
EPLNLFYIER DTGNLFCTRP VDREEYDVFD LIAYASTADG YSADLPLPLP IRVEDENDNH 240
PVFTEAIYNF EVLESSRPGT TVGWCATDR DEPDTMHTRL KYSILQQTPR SPGLFSVHPS 300
TGVITTVSHY LDREWDKYS LIMKVQDMDG QFFGLIGTST CIITVTDSND NAPTFRQNAY 360
EAFVEENAFN VEILRIPIED KDLINTANWR VNFTILKGNE NGHFKISTDK ETNEGVLSW 420
KPLNYEENRQ VNLEIGVNNE APFARDIPRV TALNRALVTV HVRDLDEGPE CTPAAQYVRI 480
KENLAVGSKI NGYKAYDPEN RNGNGLRYKK LHDPKGWITI DEISGSIITS KILDREVETP 540
KNELYNITVL AIDKDDRSCT GTLAVNIEDV NDNPPEILQE YWICKPKMG YTDILAVDPD 600
EPVHGAPFYF SLPNTSPEIS RLWSLTKVND TAARLSYQKN AGFQEYTIPI TVKDRAGQAA 660
TKLLRVNLCE CTHPTQCRAT SRSTGVILGK WAILAILLGI ALLFSVLLTL VCGVFGATKG 720
KRFPEDLAQQ NLIISNTEAP GDDRVCSANG FMTQTTNNSS QGFCGTMGSG MKNGGQETIE 780
MMKGGNQTLE SCRGAGHHHT LDSCRGGHTE VDNCRYTYSE WHSFTQPRLG EKLHRCNQNE 840
DRMPSQDYVL TYNYEGRGSP AGSVGCCSEK QEEDGLDFLN NLEPKFITLA EACTKR
Seq ID NO: 329 DNA sequence Nucleic Acid Accession #: NM_016583.2 Coding sequence : 72..842
11 21 31 41 51
GGAGTGGGGG A IGAGAGAGGA G IACCAGGACA G ICTGCTGAGA C ICTCTAAGAA G ITCCAGATAC 60 TAAGAGCAAA GATGTTTCAA ACTGGGGGCC TCATTGTCTT CTACGGGCTG TTAGCCCAGA 120 CCATGGCCCA GTTTGGAGGC CTGCCCGTGC CCCTGGACCA GACCCTGCCC TTGAATGTGA 180 ATCCAGCCCT GCCCTTGAGT CCCACAGGTC TTGCAGGAAG CTTGACAAAT GCCCTCAGCA 240 ATGGCCTGCT GTCTGGGGGC CTGTTGGGCA TTCTGGAAAA CCTTCCGCTC CTGGACATCC 300 TGAAGCCTGG AGGAGGTACT TCTGGTGGCC TCCTTGGGGG ACTGCTTGGA AAAGTGACGT 360 CAGTGATTCC TGGCCTGAAC AACATCATTG ACATAAAGGT CACTGACCCC CAGCTGCTGG 420 AACTTGGCCT TGTGCAGAGC CCTGATGGCC ACCGTCTCTA TGTCACCATC CCTCTCGGCA 480 TAAAGCTCCA AGTGAATACG CCCCTGGTCG GTGCAAGTCT GTTGAGGCTG GCTGTGAAGC 540 TGGACATCAC TGCAGAAATC TTAGCTGTGA GAGATAAGCA GGAGAGGATC CACCTGGTCC 600 TTGGTGACTG CACCCATTCC CCTGGAAGCC TGCAAATTTC TCTGCTTGAT GGACTTGGCC 660 CCCTCCCCAT TCAAGGTCTT CTGGACAGCC TCACAGGGAT CTTGAATAAA GTCCTGCCTG 720 AGTTGGTTCA GGGCAACGTG TGCCCTCTGG TCAATGAGGT TCTCAGAGGC TTGGACATCA 780 CCCTGGTGCA TGACATTGTT AACATGCTGA TCCACGGACT ACAGTTTGTC ATCAAGGTCT 840 AAGCCTTCCA GGAAGGGGCT GGCCTCTGCT GAGCTGCTTC CCAGTGCTCA CAGATGGCTG 900 GCCCATGTGC TGGAAGATGA CACAGTTGCC TTCTCTCCGA GGAACCTGCC CCCTCTCCTT 960 TCCCACCAGG CGTGTGTAAC ATCCCATGTG CCTCACCTAA TAAAATGGCT CTTCTTCTGC 1020 AAAAAAAAAA AAAAAAAAAA AAAAAAAAA
Seq ID NO: 330 Protein sequence Protein Accession #: NP 057667.1
1 11 21 31 41 51
I I I I I I
MFQTGGLIVF YGLLAQTMAQ FGGLPVPLDQ TLPLNVNPAL PLSPTGLAGS LTNALSNGLL 60 SGGLLGILEN LPLLDILKPG GGTSGGLLGG LLGKVTSVIP GLNNIIDIKV TDPQLLELGL 120 VQSPDGHRLY VTIPLGIKLQ VNTPLVGASL LRLAVKLDIT AEILAVRDKQ ERIHLVLGDC 180 THSPGSLQIS LLDGLGPLPI QGLLDSLTGI LNKVLPELVQ GNVCPLVNEV LRGLDITLVH 240 DIVNMLIHGL QFVIKV
Seq ID NO: 331 DNA sequence
Nucleic Acid Accesεion #: NM_004363.1
Coding sequence: 115..2223
1 11 21 31 41 51 1 1 I 1 1 1 I 1 | 1 1 1 CTCAGGGCAG AGGGAGGAAG GACAGCAGAC CAGACAGTCA CAGCAGCCTT GACAAAACGT 60
TCCTGGAACT CAAGCTCTTC TCCACAGAGG AGGACAGAGC AGACAGCAGA GACCATGGAG 120
TCTCCCTCGG CCCCTCCCCA CAGATGGTGC ATCCCCTGGC AGAGGCTCCT GCTCACAGCC 180
TCACTTCTAA CCTTCTGGAA CCCGCCCACC ACTGCCAAGC TCACTATTGA ATCCACGCCG 240
TTCAATGTCG CAGAGGGGAA GGAGGTGCTT CTACTTGTCC ACAATCTGCC CCAGCATCTT 300
TTTGGCTACA GCTGGTACAA AGGTGAAAGA GTGGATGGCA ACCGTCAAAT TATAGGATAT 360
GTAATAGGAA CTCAACAAGC TACCCCAGGG CCCGCATACA GTGGTCGAGA GATAATATAC 420
CCCAATGCAT CCCTGCTGAT CCAGAACATC ATCCAGAATG ACACAGGATT CTACACCCTA 480 CACGTCATAA AGTCAGATCT TGTGAATGAA GAAGCAACTG GCCAGTTCCG GGTATACCCG 540
GAGCTGCCCA AGCCCTCCAT CTCCAGCAAC AACTCCAAAC CCGTGGAGGA CAAGGATGCT 600
GTGGCCTTCA CCTGTGAACC TGAGACTCAG GACGCAACCT ACCTGTGGTG GGTAAACAAT 660
CAGAGCCTCC CGGTCAGTCC CAGGCTGCAG CTGTCCAATG GCAACAGGAC CCTCACTCTA 720
TTCAATGTCA CAAGAAATGA CACAGCAAGC TACAAATGTG AAACCCAGAA CCCAGTGAGT 780
GCCAGGCGCA GTGATTCAGT CATCCTGAAT GTCCTCTATG GCCCGGATGC CCCCACCATT 840
TCCCCTCTAA ACACATCTTA CAGATCAGGG GAAAATCTGA ACCTCTCCTG CCACGCAGCC 900
TCTAACCCAC CTGCACAGTA CTCTTGGTTT GTCAATGGGA CTTTCCAGCA ATCCACCCAA 960
GAGCTCTTTA TCCCCAACAT CACTGTGAAT AATAGTGGAT CCTATACGTG CCAAGCCCAT 1020
AACTCAGACA CTGGCCTCAA TAGGACCACA GTCACGACGA TCACAGTCTA TGCAGAGCCA 1080
CCCAAACCCT TCATCACCAG CAACAACTCC AACCCCGTGG AGGATGAGGA TGCTGTAGCC 1140
TTAACCTGTG AACCTGAGAT TCAGAACACA ACCTACCTGT GGTGGGTAAA TAATCAGAGC 1200
CTCCCGGTCA GTCCCAGGCT GCAGCTGTCC AATGACAACA GGACCCTCAC TCTACTCAGT 1260
GTCACAAGGA ATGATGTAGG ACCCTATGAG TβTGGAATCC AGAACGAATT AAGTGTTGAC 1320
CACAGCGACC CAGTCATCCT GAATGTCCTC TATGGCCCAG ACGACCCCAC CATTTCCCCC 1380
TCATACACCT ATTACCGTCC AGGGGTGAAC CTCAGCCTCT CCTGCCATGC AGCCTCTAAC 1440
CCACCTGCAC AGTATTCTTG GCTGATTGAT GGGAACATCC AGCAACACAC ACAAGAGCTC 1500
TTTATCTCCA ACATCACTGA GAAGAACAGC GGACTCTATA CCTGCCAGGC CAATAACTCA 1560
GCCAGTGGCC ACAGCAGGAC TACAGTCAAG ACAATCACAG TCTCTGCGGA GCTGCCCAAG 1620
CCCTCCATCT CCAGCAACAA CTCCAAACCC GTGGAGGACA AGGATGCTGT GGCCTTCACC 1680
TGTGAACCTG AGGCTCAGAA CACAACCTAC CTGTGGTGGG TAAATGGTCA GAGCCTCCCA 1740
GTCAGTCCCA GGCTGCAGCT GTCCAATGGC AACAGGACCC TCACTCTATT CAATGTCACA 1800
AGAAATGACG CAAGAGCCTA TGTATGTGGA ATCCAGAACT CAGTGAGTGC AAACCGCAGT 1860
GACCCAGTCA CCCTGGATGT CCTCTATGGG CCGGACACCC CCATCATTTC CCCCCCAGAC 1920
TCGTCTTACC TTTCGGGAGC GAACCTCAAC CTCTCCTGCC ACTCGGCCTC TAACCCATCC 1980
CCGCAGTATT CTTGGCGTAT CAATGGGATA CCGCAGCAAC ACACACAAGT TCTCTTTATC 2040
GCCAAAATCA CGCCAAATAA TAACGGGACC TATGCCTGTT TTGTCTCTAA CTTGGCTACT 2100
GGCCGCAATA ATTCCATAGT CAAGAGCATC ACAGTCTCTG CATCTGGAAC TTCTCCTGGT 2160
CTCTCAGCTG GGGCCACTGT CGGCATCATG ATTGGAGTGC TGGTTGGGGT TGCTCTGATA 2220
TAGCAGCCCT GGTGTAGTTT CTTCATTTCA GGAAGACTGA CAGTTGTTTT GCTTCTTCCT 2280
TAAAGCATTT GCAACAGCTA CAGTCTAAAA TTGCTTCTTT ACCAAGGATA TTTACAGAAA 2340
AGACTCTGAC CAGAGATCGA GACCATCCTA GCCAACATCG TGAAACCCCA TCTCTACTAA 2400
AAATACAAAA ATGAGCTGGG CTTGGTGGCG CGCACCTGTA GTCCCAGTTA CTCGGGAGGC 2460
TGAGGCAGGA GAATCGCTTG AACCCGGGAG GTGGAGATTG CAGTGAGCCC AGATCGCACC 2520
ACTGCACTCC AGTCTGGCAA CAGAGCAAGA CTCCATCTCA AAAAGAAAAG AAAAGAAGAC 2580
TCTGACCTGT ACTCTTGAAT ACAAGTTTCT GATACCACTG CACTGTCTGA GAATTTCCAA 2640
AACTTTAATG AACTAACTGA CAGCTTCATG AAACTGTCCA CCAAGATCAA GCAGAGAAAA 2700
TAATTAATTT CATGGGACTA AATGAACTAA TGAGGATTGC TGATTCTTTA AATGTCTTGT 2760
TTCCCAGATT TCAGGAAACT TAAGCTATCC ACTCTTACAG CAATTTGATA 2820
AAATATACTT TTGTGAACAA AAATTGAGAC ATTTACATTT TCTCCCTATG TGGTCGCTCC 2880
AGACTTGGGA AACTATTCAT GAATATTTAT ATTGTATGGT AATATAGTTA TTGCACAAGT 2940
TCAATAAAAA TCTGCTCTTT GTATAACAGA AAAA
Seq ID NO: 332 Protein sequence Protein Accession it: NP 004354.1
11 21 31 41 51
MESPSAPPHR WCIPWQRLLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLVHNLPQ 60 HLFGYSWYKG ERVDGNRQII GYVIGTQQAT PGPAYSGREI IYPNASLLIQ NIIQNDTGFY 120 TLHVIKSDLV NEEATGQFRV YPELPKPSIS SNNSKPVEDK DAVAFTCEPE TQDATYLWWV 180 NNQSLPVSPR LQLSNGNRTL TLFNVTRNDT ASYKCETQNP VSARRSDSVI LNVLYGPDAP 240 TISPLNTSYR SGENLNLSCH AASNPPAQYS WFVNGTFQQS TQELFIPNIT VNNSGSYTCQ 300 AHNSDTGLNR TTVTTITVYA EPPKPFITSN NSNPVEDEDA VALTCEPEIQ NTTYLWWVNN 360 QSLPVSPRLQ LSNDNRTLTL LSVTRNDVGP YECGIQNELS VDHSDPVILN VLYGPDDPTI 420 SPSYTYYRPG VNLSLSCHAA SNPPAQYSWL IDGNIQQHTQ ELFISNITEK NSGLYTCQAN 480 NSASGHSRTT VKTITVSAEL PKPSISSNNS KPVEDKDAVA FTCEPEAQNT TYLWWVNGQS 540 LPVSPRLQLS NGNRTLTLFN VTRNDARAYV CGIQNSVSAN RSDPVTLDVL YGPDTPIISP 600 PDSSYLSGAN LNLSCHSASN PSPQYSWRIN GIPQQHTQVL FIAKITPNNN GTYACFVSNL 660 ATGRNNSIVK SITVSASGTS PGLSAGATVG IMIGVLVGVA LI
Seq ID NO: 333 DNA sequence
Nucleic Acid Accession #: NM_006952.1
Coding sequence: 11..793
11 21 31 41 51
AATCCCGACA ATGGCGAAAG ACAACTCAAC TGTTCGTTGC TTCCAGGGCC TGCTGATTTT 60 TGGAAATGTG ATTATTGGTT GTTGCGGCAT TGCCCTGACT GCGGAGTGCA TCTTCTTTGT 120 ATCTGACCAA CACAGCCTCT ACCCACTGCT TGAAGCCACC GACAACGATG ACATCTATGG 180 GGCTGCCTGG ATCGGCATAT TTGTGGGCAT CTGCCTCTTC TGCCTGTCTG TTCTAGGCAT 240 TGTAGGCATC ATGAAGTCCA GCAGGAAAAT TCTTCTGGCG TATTTCATTC TGATGTTTAT 300 AGTATATGCC TTTGAAGTGG CATCTTGTAT CACAGCAGCA ACACAACGAG ACTTTTTCAC 360 ACCCAACCTC TTCCTGAAGC AGATGCTAGA GAGGTACCAA AACAACAGCC CTCCAAACAA 420 TGATGACCAG TGGAAAAACA ATGGAGTCAC CAAAACCTGG GACAGGCTCA TGCTCCAGGA 480 CAATTGCTGT GGCGTAAATG GTCCATCAGA CTGGCAAAAA TACACATCTG CCTTCCGGAC 540 TGAGAATAAT GATGCTGACT ATCCCTGGCC TCGTCAATGC TGTGTTATGA ACAATCTTAA 600 AGAACCTCTC AACCTGGAGG CTTGTAAACT AGGCGTGCCT GGTTTTTATC ACAATCAGGG 660 CTGCTATGAA CTGATCTCTG GTCCAATGAA CCGACACGCC TGGGGGGTTG CCTGGTTTGG 720 ATTTGCCATT CTCTGCTGGA CTTTTTGGGT TCTCCTGGGT ACCATGTTCT ACTGGAGCAG 780 AATTGAATAT TAAGAA
Seq ID NO: 334 Protein sequence Protein Accession tf: NP 008883.1 1 11 21 31 41 51
I I I I I I
MAKDNSTVRC FQGLLIFGNV IIGCCGIALT AECIFFVSDQ HSLYPLLEAT DNDDIYGAAW 60 IGIFVGICLF CLSVLGIVGI MKSSRKILLA YFILMFIVYA FEVASCITAA TQRDFFTPNL 120 FLKQMLERYQ NNSPPNNDDQ WKNNGVTKTW DRLMLQDNCC GVNGPSDWQK YTSAFRTENN 180 DADYPWPRQC CVMNNLKEPL NLEACKLGVP GFYHNQGCYE LISGPMNRHA WGVAWFGFAI 240 LCWTFWVLLG TMFYWSRIEY
Seq ID NO: 335 DNA sequence
Nucleic Acid Accesεion #: NM_002638.1
Coding sequence: 120..473
60
120
Figure imgf001084_0001
180
AGGCAGCTGT CACGGGAGTT CCTGTTAAAG GTCAAGACAC TGTCAAAGGC CGTGTTCCAT 240
TCAATGGACA AGATCCCGTT AAAGGACAAG TTTCAGTTAA AGGTCAAGAT AAAGTCAAAG 300
CGCAAGAGCC AGTCAAAGGT CCAGTCTCCA CTAAGCCTGG CTCCTGCCCC ATTATCTTGA 360
TCCGGTGCGC CATGTTGAAT CCCCCTAACC GCTGCTTGAA AGATACTGAC TGCCCAGGAA 420
TCAAGAAGTG CTGTGAAGGC TCTTGCGGGA TGGCCTGTTT CGTTCCCCAG TGAAGGGAGC 480
CGGTCCTTGC TGCACCTGTG CCGTCCCCAG AGCTACAGGC CCCATCTGGT CCTAAGTCCC 540
TGCTGCCCTT CCCCTTCCCA CACTGTCCAT TCTTCCTCCC ATTCAGGATG CCCACGGCTG 600
GAGCTGCCTC TCTCATCCAC TTTCCAATAA A
Seq ID NO: 336 Protein sequence
MRASSFLIW VFLIAGTLVL EAAVTGVPVK GQDTVKGRVP FNGQDPVKGQ VSVKGQDKVK AQEPVKGPVS TKPGSCPIIL IRCAMLNPPN RCLKDTDCPG IKKCCEGSCG MACFVPQ
Seq ID NO: 337 DNA sequence
Nucleic Acid Acceεsion #: NM_001793.2
Coding sequence: 71..2560
11 21 31 41 51
I I I I I
AAAGGGGCAA GAGCTGAGCG GAACACCGGC CCGCCGTCGC GGCAGCTGCT TCACCCCTCT 60
CTCTGCAGCC ATGGGGCTCC CTCGTGGACC TCTCGCGTCT CTCCTCCTTC TCCAGGTTTG 120
CTGGCTGCAG TGCGCGGCCT CCGAGCCGTG CCGGGCGGTC TTCAGGGAGG CTGAAGTGAC 180
CTTGGAGGCG GGAGGCGCGG AGCAGGAGCC CGGCCAGGCG CTGGGGAAAG TATTCATGGG 240
CTGCCCTGGG CAAGAGCCAG CTCTGTTTAG CACTGATAAT GATGACTTCA CTGTGCGGAA 300
TGGCGAGACA GTCCAGGAAA GAAGGTCACT GAAGGAAAGG AATCCATTGA AGATCTTCCC 360
ATCCAAACGT ATCTTACGAA GACACAAGAG AGATTGGGTG GTTGCTCCAA TATCTGTCCC 420
TGAAAATGGC AAGGGTCCCT TCCCCCAGAG ACTGAATCAG CTCAAGTCTA ATAAAGATAG 480
AGACACCAAG ATTTTCTACA GCATCACGGG GCCGGGGGCA GACAGCCCCC CTGAGGGTGT 540
CTTCGCTGTA GAGAAGGAGA CAGGCTGGTT GTTGTTGAAT AAGCCACTGG ACCGGGAGGA 600
GATTGCCAAG TATGAGCTCT TTGGCCACGC TGTGTCAGAG AATGGTGCCT CAGTGGAGGA 660
CCCCATGAAC ATCTCCATCA TCGTGACCGA CCAGAATGAC CACAAGCCCA AGTTTACCCA 720
GGACACCTTC CGAGGGAGTG TCTTAGAGGG AGTCCTACCA GGTACTTCTG TGATGCAGGT 780
GACAGCCACG GATGAGGATG ATGCCATCTA CACCTACAAT GGGGTGGTTG CTTACTCCAT 840
CCATAGCCAA GAACCAAAGG ACCCACACGA CCTCATGTTC ACCATTCACC GGAGCACAGG 900
CACCATCAGC GTCATCTCCA GTGGCCTGGA CCGGGAAAAA CTCCCTGAGT ACACACTGAC 960
CATCCAGGCC ACAGACATGG ATGGGGACGG CTCCACCACC ACGGCAGTGG CAGTAGTGGA 1020
GATCCTTGAT GCCAATGACA ATGCTCCCAT GTTTGACCCC CAGAAGTACG AGGCCCATGT 1080
GCCTGAGAAT GCAGTGGGCC ATGAGGTGCA GAGGCTGACG GTCACTGATC TGGACGCCCC 1140
CAACTCACCA GCGTGGCGTG CCACCTACCT TATCATGGGC GCTGACGACG GGGACCATTT 1200
TACCATCACC ACCCACCCTG AGAGCAACCA GGGCATCCTG ACAACCAGGA AGGGTTTGGA 1260
TTTTGAGGCC AAAAACCAGC ACACCCTGTA CGTTGAAGTG ACCAACGAGG CCCCTTTTGT 1320
GCTGAAGCTC CCAACCTCCA CAGCCACCAT AGTGGTCCAC GTGGAGGATG TGAATGAGGC 1380
ACCTGTGTTT GTCCCACCCT CCAAAGTCGT TGAGGTCCAG GAGGGCATCC CCACTGGGGA 1440
GCCTGTGTGT GTCTACACTG CAGAAGACCC TGACAAGGAG AATCAAAAGA TCAGCTACCG 1500
CATCCTGAGA GACCCAGCAG GGTGGCTAGC CATGGACCCA GACAGTGGGC AGGTCACAGC 1560
TGTGGGCACC CTCGACCGTG AGGATGAGCA GTTTGTGAGG AACAACATCT ATGAAGTCAT 1620
GGTCTTGGCC ATGGACAATG GAAGCCCTCC CACCACTGGC ACGGGAACCC TTCTGCTAAC 1680
ACTGATTGAT GTCAATGACC ATGGCCCAGT CCCTGAGCCC CGTCAGATCA CCATCTGCAA 1740
CCAAAGCCCT GTGCGCCAGG TGCTGAACAT CACGGACAAG GACCTGTCTC CCCACACCTC 1800
CCCTTTCCAG GCCCAGCTCA CAGATGACTC AGACATCTAC TGGACGGCAG AGGTCAACGA 1860
GGAAGGTGAC ACAGTGGTCT TGTCCCTGAA GAAGTTCCTG AAGCAGGATA CATATGACGT 1920
GCACCTTTCT CTGTCTGACC ATGGCAACAA AGAGCAGCTG ACGGTGATCA GGGCCACTGT 1980
GTGCGACTGC CATGGCCATG TCGAAACCTG CCCTGGACCC TGGAAGGGAG GTTTCATCCT 2040
CCCTGTGCTG GGGGCTGTCC TGGCTCTGCT GTTCCTCCTG CTGGTGCTGC TTTTGTTGGT 2100
GAGAAAGAAG CGGAAGATCA AGGAGCCCCT CCTACTCCCA GAAGATGACA CCCCTGACAA 2160
CGTCTTCTAC TATGGCGAAG AGGGGGGTGG CGAAGAGGAC CAGGACTATG ACATCACCCA 2220
GCTCCACCGA GGTCTGGAGG CCAGGCCGGA GGTGGTTCTC CGCAATGACG TGGCACCAAC 2280
CATCATCCCG ACACCCATGT ACCGTCCTCG GCCAGCCAAC CCAGATGAAA TCGGCAACTT 2340
TATAATTGAG AACCTGAAGG CGGCTAACAC AGACCCCACA GCCCCGCCCT ACGACACCCT 2400
CTTβGTGTTC GACTATGAGG GCAGCGGCTC CGACGCCGCG TCCCTGAGCT CCCTCACCTC 2460
CTCCGCCTCC GACCAAGACC AAGATTACGA TTATCTGAAC GAGTGGGGCA GCCGCTTCAA 2520
GAAGCTGGCA GACATGTACG GTGGCGGGGA GGACGACTAG GCGGCCTGCC TGCAGGGCTG 2580 GGGACCAAAC GTCAGGCCAC AGAGCATCTC CAAGGGGTCT CAGTTCCCCC TTCAGCTGAG 2640
GACTTCGGAG CTTGTCAGGA AGTGGCCGTA GCAACTTGGC GGAGACAGGC TATGAGTCTG 2700
ACGTTAGAGT GGTTGCTTCC TTAGCCTTTC AGGATGGAGG AATGTGGGCA GTTTGACTTC 2760
AGCACTGAAA ACCTCTCCAC CTGGGCCAGG GTTGCCTCAG AGGCCAAGTT TCCAGAAGCC 2820
TCTTACCTGC CGTAAAATGC TCAACCCTGT GTCCTGGGCC TGGGCCTGCT GTGACTGACC 2880
TACAGTGGAC TTTCTCTCTG GAATGGAACC TTCTTAGGCC TCCTGGTGCA ACTTAATTTT 2940
TTTTTTTAAT GCTATCTTCA AAACGTTAGA GAAAGTTCTT CAAAAGTGCA GCCCAGAGCT 3000
GCTGGGCCCA CTGGCCGTCC TGCATTTCTG GTTTCCAGAC CCCAATGCCT CCCATTCGGA 3060
TGGATCTCTG CGTTTTTATA CTGAGTGTGC CTAGGTTGCC CCTTATTTTT TATTTTCCCT 3120
GTTGCGTTGC TATAGATGAA GGGTGAGGAC AATCGTGTAT ATGTACTAGA ACTTTTTTAT 3180 TAAAGAAACT TTTCCCAGAA AAAAA
Seq ID NO: 338 Protein sequence Protein Accession ft: NP_001784.2
1 11 21 31 41 51
I I I I I I
MGLPRGPLAS LLLLQVCWLQ CAASEPCRAV FREAEVTLEA GGAEQEPGQA LGKVFMGCPG 60
QEPALFSTDN DDFTVRNGET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENG 120
KGPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK 180
YELFGHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RGSVLEGVLP GTSVMQVTAT 240
DEDDAIYTYN GWAYSIHSQ EPKDPHDLMF TIHRSTGTIS VISSGLDREK VPEYTLTIQA 300
TDMDGDGSTT TAVAWEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP 360
AWRATYLIMG GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL 420
PTSTATIWH VEDVNEAPVF VPPSKWEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR 480
DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTG TGTLLLTLID 540
VNDHGPVPEP RQITICNQSP VRQVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD 600
T LSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL 660
GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YGEEGGGEED QDYDITQLHR 720
GLEARPEWL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF 780 DYEGSGSDAA SLSSLTSSAS DQDQDYDYLN EWGSRFKKLA DMYGGGEDD
Seq ID NO: 339 DNA sequence Nucleic Acid Accesεion ft: Eos sequence Coding sequence: 1..672
1 11 21 31 41 51
I I I I I I
ATGAGGCTCC AAAGACCCCG ACAGGCCCCG GCGGGTGGGA GGCGCGCGCC CCGGGGCGGG 60
CGGGGCTCCC CCTACCGGCC AGACCCGGGG AGAGGCGCGC GGAGGCTGCG AAGGTTCCAG 120
AAGGGCGGGG AGGGGGCGCC GCGCGCTGAC CCTCCCTGGG CACCGCTGGG GACGATGGCG 180
CTGCTCGCCT TGCTGCTGGT CGTGGCCCTA CCGCGGGTGT GGACAGACGC CAACCTGACT 240
GCGAGACAAC GAGATCCAGA GGACTCCCAG CGAACGGACG AGGGTGACAA TAGAGTGTGG 300
TGTCATGTTT GTGAGAGAGA AAACACTTTC GAGTGCCAGA ACCCAAGGAG GTGCAAATGG 360
ACAGAGCCAT ACTGCGTTAT AGCGGCCGTG AAAATATTTC CACGTTTTTT CATGGTTGCG 420
AAGCAGTGCT CCGCTGGTTG TGCAGCGATG GAGAGACCCA AGCCAGAGGA GAAGCGGTTT 480
CTCCTGGAAG AGCCCATGCC CTTCTTTTAC CTCAAGTGTT GTAAAATTCG CTACTGCAAT 540
TTAGAGGGGC CACCTATCAA CTCATCAGTG TTCAAAGAAT ATGCTGGGAG CATGGGTGAG 600
AGCTGTGGTG GGCTGTGGCT GGCCATCCTC CTGCTGCTGG CCTCCATTGC AGCCGGCCTC 660 AGCCTGTCTT GA
Seq ID NO: 340 Protein sequence Protein Accession # : Eos sequence
1 11 21 31 41 51
I I I I I I
MRLQRPRQAP AGGRRAPRGG RGSPYRPDPG RGARRLRRFQ KGGEGAPRAD PPWAPLGTMA 60
LLALLLWAL PRVWTDANLT ARQRDPEDSQ RTDEGDNRVW CHVCERENTF ECQNPRRCKW 120
TEPYCVIAAV KIFPRFFMVA KQCSAGCAAM ERPKPEEKRF LLEEPMPFFY LKCCKIRYCN 180 LEGPPINSSV FKEYAGSMGE SCGGLWLAIL LLLASIAAGL SLS
Seq ID NO : 341 DNA sequence
Nucleic Acid Accession ft : XM_035292 .2
Coding sequence : 53 . . 1576
1 11 21 31 41 51
I I I I I I
GCTCGCTGGG CCGCGGCTCC CGGGTGTCCC AGGCCCGGCC GGTGCGCAGA GCATGGCGGG 60
TGCGGGCCCG AAGCGGCGCG CGCTAGCGGC GCCGGCGGCC GAGGAGAAGG AAGAGGCGCG 120
GGAGAAGATG CTGGCCGCCA AGAGCGCGGA CGGCTCGGCG CCGGCAGGCG AGGGCGAGGG 180
CGTGACCCTG CAGCGGAACA TCACGCTGCT CAACGGCGTG GCCATCATCG TGGGGACCAT 240
TATCGGCTCG GGCATCTTCG TGACGCCCAC GGGCGTGCTC AAGGAGGCAG GCTCGCCGGG 300
GCTGGCGCTG GTGGTGTGGG CCGCGTGCGG CGTCTTCTCC ATCGTGGGCG CGCTCTGCTA 360
CGCGGAGCTC GGCACCACCA TCTCCAAATC GGGCGGCGAC TACGCCTACA TGCTGGAGGT 420
CTACGGCTCG CTGCCCGCCT TCCTCAAGCT CTGGATCGAG CTGCTCATCA TCCGGCCTTC 480
ATCGCAGTAC ATCGTGGCCC TGGTCTTCGC CACCTACCTG CTCAAGCCGC TCTTCCCCAC 540
CTGCCCGGTG CCCGAGGAGG CAGCCAAGCT CGTGGCCTGC CTCTGCCTGC TGCTGCTCAC 600
GGCCGTGAAC TGCTACAGCG TGAAGGCCGC CACCCGGGTC CAGGATGCCT TTGCCGCCGC 660
CAAGCTCCTG GCCCTGGCCC TGATCATCCT GCTGGGCTTC GTCCAGATCG GAAAGGGTGA 720
TGTGTCCAAT CTAGATCCCA ACTTCTCATT TGAAGGCACC AAACTGGATG TGGGGAACAT 780
TGTGCTGGCA TTATACAGCG GCCTCTTTGC CTATGGAGGA TGGAATTACT TGAATTTCGT 840
CACAGAGGAA ATGATCAACC CCTACAGAAA CCTGCCCCTG GCCATCATCA TCTCCCTGCC 900
CATCGTGACG CTGGTGTACG TGCTGACCAA CCTGGCCTAC TTCACCACCC TGTCCACCGA 960
GCAGATGCTG TCGTCCGAGG CCGTGGCCGT GGACTTCGGG AACTATCACC TGGGCGTCAT 1020 GTCCTGGATC ATCCCCGTCT TCGTGGGCCT GTCCTGCTTC GGCTCCGTCA ATGGGTCCCT 1080 GTTCACATCC TCCAGGCTCT TCTTCGTGGG GTCCCGGGAA GGCCACCTβC CCTCCATCCT 1140 CTCCATGATC CACCCACAGC TCCTCACCCC CGTGCCGTCC CTCGTGTTCA CGTGTGTGAT 1200 GACGCTGCTC TACGCCTTCT CCAAGGACAT CTTCTCCGTC ATCAACTTCT TCAGCTTCTT 1260 CAACTGGCTC TGCGTGGCCC TGGCCATCAT CGGCATGATC TGGCTGCGCC ACAGAAAGCC 1320 TGAGCTTGAG CGGCCCATCA AGGTGAACCT GGCCCTGCCT GTGTTCTTCA TCCTGGCCTG 1380 CCTCTTCCTG ATCGCCGTCT CCTTCTGGAA GACACCCGTG GAGTGTGGCA TCGGCTTCAC 1440 CATCATCCTC AGCGGGCTGC CCGTCTACTT CTTCGGGGTC TGGTGGAAAA ACAAGCCCAA 1500 GTGGCTCCTC CAGGGCATCT TCTCCACGAC CGTCCTGTGT CAGAAGCTCA TGCAGGTGGT 1560 CCCCCAGGAG ACATAGCCAG GAGGCCGAGT GGCTGCCGGA GGAGCATGC
Seq ID NO: 342 Protem sequence Protem Accession ft: XP_035292.2
1 11 21 31
MAGAGPKRRA LAAPAAEEKE EAREKMLAAK SADGSAPAGE GEGVTLQRNI TLLNGVAIIV 60
GTIIGSGIFV TPTGVLKEAG SPGLALWWA ACGVFSIVGA LCYAELGTTI SKSGGDYAYM 120
LEVYGSLPAF LKLWIELLII RPSSQYIVAL VFATYLLKPL FPTCPVPEEA AKLVACLCVL 180
LLTAVNCYSV KAATRVQDAF AAAKLLALAL IILLGFVQIG KGDVSNLDPN FSFEGTKLDV 240
GNIVLALYSG LFAYGGWNYL NFVTEEMINP YRNLPLAIII SLPIVTLVYV LTNLAYPTTL 300
STEQMLSSEA VAVDFGNYHL GVMS IIPVF VGLSCFGSVN GSLFTSSRLF FVGSREGHLP 360
SILSMIHPQL LTPVPSLVFT CVMTLLYAFS KDIFSVINFF SFFNWLCVAL AIIGMIWLRH 420
RKPELERPIK VNLALPVFFI LACLFLIAVS FWKTPVECGI GFTIILSGLP VYFFGVWWKN 480
KPKWLLQGIF STTVLCQKLM QWPQET
Seq ID NO: 343 DNA sequence
Nucleic Acid Accession it: NM_005268.1 Coding sequence: 168..989
11 21 31 41 51
TAAAAAGCAA AAGAATTCGC GGCCGCGTCG ACACGGGCTT CCCCGAAAAC CTTCCCCGCT 60 TCTGGATATG AAATTCAAGC TGCTTGCTGA GTCCTATTGC CGGCTGCTGG GAGCCAGGAG 120 AGCCCTGAGG AGTAGTCACT CAGTAGCAGC TGACGCGTGG GTCCACCATG AACTGGAGTA 180 TCTTTGAGGG ACTCCTGAGT GGGGTCAACA AGTACTCCAC AGCCTTTGGG CGCATCTGGC 240 TGTCTCTGGT CTTCATCTTC CGCGTGCTGG TGTACCTGGT GACGGCCGAG CGTGTGTGGA 300 GTGATGACCA CAAGGACTTC GACTGCAATA CTCGCCAGCC CGGCTGCTCC AACGTCTGCT 360 TTGATGAGTT CTTCCCTGTG TCCCATGTGC GCCTCTGGGC CCTGCAGCTT ATCCTGGTGA 420 CATGCCCCTC ACTGCTCGTG GTCATGCACG TGGCCTACCG GGAGGTTCAG GAGAAGAGGC 480 ACCGAGAAGC CCATGGGGAG AACAGTGGGC GCCTCTACCT GAACCCCβGC AAGAAGCGGG 540 GTGGGCTCTG GTGGACATAT GTCTGCAGCC TAGTGTTCAA GGCGAGCGTG GACATCGCCT 600 TTCTCTATGT GTTCCACTCA TTCTACCCCA AATATATCCT CCCTCCTGTG GTCAAGTGCC 660 ACGCAGATCC ATGTCCCAAT ATAGTGGACT GCTTCATCTC CAAGCCCTCA GAGAAGAACA 720 TTTTCACCCT CTTCATGGTG GCCACAGCTG CCATCTGCAT CCTGCTCAAC CTCGTGGAGC 780 TCATCTACCT GGTGAGCAAG AGATGCCACG AGTGCCTGGC AGCAAGGAAA GCTCAAGCCA 840 TGTGCACAGG TCATCACCCC CACGGTACCA CCTCTTCCTG CAAACAAGAC GACCTCCTTT 900 CGGGTGACCT CATCTTTCTG GGCTCAGACA GTCATCCTCC TCTCTTACCA GACCGCCCCC 960 GAGACCATGT GAAGAAAACC ATCTTGTGAG GGGCTGCCTG GACTGGTCTG GCAGGTTGGG 1020 CCTGGATGGG GAGGCTCTAG CATCTCTCAT AGGTGCAACC TGAGAGTGGG GGAGCTAAGC 1080 CATGAGGTAG GGGCAGGCAA GAGAGAGGAT TCAGACGCTC TGGGAGCCAG TTCCTAGTCC 1140 TCAACTCCAG CCACCTGCCC CAGCTCGACG GCACTGGGCC AGTTCCCCCT CTGCTCTGCA 1200 GCTCGGTTTC CTTTTCTAGA ATGGAAATAG TGAGGGCCAA TGC
Seq ID NO: 344 Protein sequence Protein Accession ft: NP 005259.1
11 21 31 41 51
I I I I I
MNWSIFEGLL SGVNKYSTAF GRIWLSLVFI FRVLVYLVTA ERVWSDDHKD FDCNTRQPGC 60 SNVCFDEFFP VSHVRLWALQ LILVTCPSLL WMHVAYREV QEKRHREAHG ENSGRLYLNP 120 GKKRGGLWWT YVCSLVFKAS VDIAFLYVFH SFYPKYILPP WKCHADPCP NIVDCFISKP 180 SEKNIFTLFM VATAAICILL NLVELIYLVS KRCHECLAAR KAQAMCTGHH PHGTTSSCKQ 240 DDLLSGDLIF LGSDSHPPLL PDRPRDHVKK TIL
Seq ID NO: 345 DNA sequence
Nucleic Acid Accession #: NM_002391.1
Coding sequence: 26..457
11 21 31 41 51
CGGGCGAAGC AGCGCGGGCA GCGAGATGCA GCACCGAGGC TTCCTCCTCC TCACCCTCCT 60 CGCCCTGCTG GCGCTCACCT CCGCGGTCGC CAAAAAGAAA GATAAGGTGA AGAAGGGCGG 120 CCCGGGGAGC GAGTGCGCTG AGTGGGCCTβ GGGGCCCTGC ACCCCCAGCA GCAAGGATTG 180 CGGCGTGGGT TTCCGCGAGG GCACCTGCGG GGCCCAGACC CAGCGCATCC GGTGCAGGGT 240 GCCCTGCAAC TGGAAGAAGG AGTTTGGAGC CGACTGCAAG TACAAGTTTG AGAACTGGGG 300 TGCGTGTGAT GGGGGCACAG GCACCAAAGT CCGCCAAGGC ACCCTGAAGA AGGCGCGCTA 360 CAATGCTCAG TGCCAGGAGA CCATCCGCGT CACCAAGCCC TGCACCCCCA AGACCAAAGC 420 AAAGGCCAAA GCCAAGAAAG GGAAGGGAAA GGACTAGACG CCAAGCCTGG ATGCCAAGGA 480 GCCCCTGGTG TCACATGGGG CCTGGCCACβ CCCTCCCTCT CCCAGGCCCG AGATGTGACC 540 CACCAGTGCC TTCTGTCTGC TCGTTAGCTT TAATCAATCA TGCCCTGCCT TGTCCCTCTC 600 ACTCCCCAGC CCCACCCCTA AGTGCCCAAA GTGGGGAGGG ACAAGGGATT CTGGGAAGCT 660 TGAGCCTCCC CCAAAGCAAT GTGAGTCCCA GAGCCCGCTT TTGTTCTTCC CCACAATTCC 720 ATTACTAAGA AACACATCAA ATAAACTGAC TTTTTCCCCC CAATAAAAGC TCTTCTTTTT 780 TAATAT
Seq ID NO: 346 Protein sequence '
Protein Accession #: NP_002382.1
1 11 21 31 41 51
I I I I I I
MQHRGFLLLT LLALLALTSA VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT 60 CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI 120 0 RVTKPCTPKT KAKAKAKKGK GKD
Seq ID NO: 347 DNA sequence
Nucleic Acid Accession ft: NM_006783.1
Coding sequence: 1..786 5
1 11 21 31 41 51
I I I I I I
ATGGATTGGG GGACGCTGCA CACTTTCATC GGGGGTGTCA ACAAACACTC CACCAGCATC 60
GGGAAGGTGT GGATCACAGT CATCTTTATT TTCCGAGTCA TGATCCTAGT GGTGGCTGCC 120 0 CAGGAAGTGT GGGGTGACGA GCAAGAGGAC TTCGTCTGCA ACACACTGCA ACCGGGATGC 180
AAAAATGTGT GCTATGACCA CTTTTTCCCG GTGTCCCACA TCCGGCTGTG GGCCCTCCAG 240
CTGATCTTCG TCTCCACCCC AGCGCTGCTG GTGGCCATGC ATGTGGCCTA CTACAGGCAC 300
GAAACCACTC GCAAGTTCAG GCGAGGAGAG AAGAGGAATG ATTTCAAAGA CATAGAGGAC 360
ATTAAAAAGC ACAAGGTTCG GATAGAGGGG TCGCTGTGGT GGACGTACAC CAGCAGCATC 420 5 TTTTTCCGAA TCATCTTTGA AGCAGCCTTT ATGTATGTGT TTTACTTCCT TTACAATGGG 480
TACCACCTGC CCTGGGTGTT GAAATGTGGG ATTGACCCCT GCCCCAACCT TGTTGACTGC 540
TTTATTTCTA GGCCAACAGA GAAGACCGTG TTTACCATTT TTATGATTTC TGCGTCTGTG 600
ATTTGCATGC TGCTTAACGT GGCAGAGTTG TGCTACCTGC TGCTGAAAGT GTGTTTTAGG 660
AGATCAAAGA GAGCACAGAC GCAAAAAAAT CACCCCAATC ATGCCCTAAA GGAGAGTAAG 720 0 CAGAATGAAA TGAATGAGCT GATTTCAGAT AGTGGTCAAA ATGCAATCAC AGGTTTCCCA 780 AGCTAA
Seq ID NO: 348 Protein sequence Protein Accession ft: NP_006774.1 5
1 11 21 31 41 51
1 I I I I I
MDWGTLHTFI GGVNKHSTSI GKVWITVIFI FRVMILWAA QEVWGDEQED FVCNTLQPGC 60
KNVCYDHFFP VSHIRLWALQ LIFVSTPALL VAMHVAYYRH ETTRKFRRGE KRNDFKDIED 120 0 IKKHKVRIEG SLWWTYTSSI FFRIIFEAAF MYVFYFLYNG YHLPWVLKCG IDPCPNLVDC 180
FISRPTEKTV FTIFMISASV ICMLLNVAEL CYLLLKVCFR RSKRAQTQKN HPNHALKESK 240 QNEMNELISD SGQNAITGFP S
Seq ID NO : 349 DNA sequence 5 Nucleic Acid Accession # : NM 002571 . 1
Coding sequence : 99 . - 587
1 11 21 31 41 51 0 I I I I I I
CATCCCTCTG GCTCCAGAGC TCAGAGCCAC CCACAGCCGC AGCCATGCTG TGCCTCCTGC 60
TCACCCTGGG CGTGGCCCTG GTCTGTGGTG TCCCGGCCAT GGACATCCCC CAGACCAAGC 120
AGGACCTGGA GCTCCCAAAG TTGGCAGGGA CCTGGCACTC CATGGCCATG GCGACCAACA 180
ACATCTCCCT CATGGCGACA CTGAAGGCCC CTCTGAGGGT CCACATCACC TCACTGTTGC 240
CCACCCCCGA GGACAACCTG GAGATCGTTC TGCACAGATG GGAGAACAAC AGCTGTGTTG 300 5 AGAAGAAGGT CCTTGGAGAG AAGACTGGGA ATCCAAAGAA GTTCAAGATC AACTATACGG 360
TGGCGAACGA GGCCACGCTG CTCGATACTG ACTACGACAA TTTCCTGTTT CTCTGCCTAC 420
AGGACACCAC CACCCCCATC CAGAGCATGA TGTGCCAGTA CCTGGCCAGA GTCCTGGTGG 480
AGGACGATGA GATCATGCAG GGATTCATCA GGGCTTTCAG GCCCCTGCCC AGGCACCTAT 540
GGTACTTGCT GGACTTGAAA CAGATGGAAG AGCCGTGCCG TTTCTAGCTC ACCTCCGCCT 600 0 CCAGGAAGAC CAGACTCCCA CCCTTCCACA GCTCCAGAGC AGTGGGACTT CCTCCTGCCC 660
TTTCAAAGAA TAACCACAGC TCAGAAGACG ATGACGTGGT CATCTGTGTC GCCATCCCCT 720
TCCTGCTGCA CACCTGCACC ATTGCCATGG GGAGGCTGCT CCCTGGGGGC AGAGTCTCTG 780 GCAGAGGTTA TTAATAAACC CTTGGAGCAT G 5 Seq ID NO: 350 Protein sequence Protein Accession #: NP_002562.1
1 11 21 31 41 51
1 I I I I I
70 MDIPQTKQDL ELPKLAGTWH SMAMATNNIS LMATLKAPLR VHITSLLPTP EDNLEIVLHR 60 WENNSCVEKK VLGEKTGNPK KFKINYTVAN EATLLDTDYD NFLFLCLQDT TTPIQSMMCQ 120 YLARVLVEDD EIMQGFIRAF RPLPRHLWYL LDLKQMEEPC RF
_ Seq ID NO: 351 DNA sequence
/5 Nucleic Acid Accession #: NM_006500.1
Coding sequence: 27..1967
1 11 21 31 41 51
80 I I I I I I
ACTTGCGTCT CGCCCTCCGG CCAAGCATGG GGCTTCCCAG GCTGGTCTGC GCCTTCTTGC 60
TCGCCGCCTG CTGCTGCTGT CCTCGCGTCG CGGGTGTGCC CGGAGAGGCT GAGCAGCCTG 120
CGCCTGAGCT GGTGGAGGTG GAAGTGGGCA GCACAGCCCT TCTGAAGTGC GGCCTCTCCC 180
AGTCCCAAGG CAACCTCAGC CATGTCGACT GGTTTTCTGT CCACAAGGAG AAGCGGACGC 240
TCATCTTCCG TGTGCGCCAG GGCCAGGGCC AGAGCGAACC TGGGGAGTAC GAGCAGCGGC 300 TCAGCCTCCA GGACAGAGGG GCTACTCTGG CCCTGACTCA AGTCACCCCC CAAGACGAGC 360
GCATCTTCTT GTGCCAGGGC AAGCGCCCTC GGTCCCAGGA GTACCGCATC CAGCTCCGCG 420
TCTACAAAGC TCCGGAGGAG CCAAACATCC AGGTCAACCC CCTGGGCATC CCTGTGAACA 480
GTAAGGAGCC TGAGGAGGTC GCTACCTGTG TAGGGAGGAA CGGGTACCCC ATTCCTCAAG 540
TCATCTGGTA CAAGAATGGC CGGCCTCTGA AGGAGGAGAA GAACCGGGTC CACATTCAGT 600
CGTCCCAGAC TGTGGAGTCG AGTGGTTTGT ACACCTTGCA GAGTATTCTG AAGGCACAGC 660
TGGTTAAAGA AGACAAAGAT GCCCAGTTTT ACTGTGAGCT CAACTACCGG CTGCCCAGTG 720
GGAACCACAT GAAGGAGTCC AGGGAAGTCA CCGTCCCTGT TTTCTACCCG ACAGAAAAAG 780
TGTGGCTGGA AGTGGAGCCC GTGGGAATGC TGAAGGAAGG GGACCGCGTG GAAATCAGGT 840 0 GTTTGGCTGA TGGCAACCCT CCACCACACT TCAGCATCAG CAAGCAGAAC CCCAGCACCA 900
GGGAGGCAGA GGAAGAGACA ACCAACGACA ACGGGGTCCT GGTGCTGGAG CCTGCCCGGA 960
AGGAACACAG TGGGCGCTAT GAATGTCAGG CCTGGAACTT GGACACCATG ATATCGCTGC 1020
TGAGTGAACC ACAGGAACTA CTGGTGAACT ATGTGTCTGA CGTCCGAGTG AGTCCCGCAG 1080
CCCCTGAGAG ACAGGAAGGC AGCAGCCTCA CCCTGACCTG TGAGGCAGAG AGTAGCCAGG 1140 5 ACCTCGAGTT CCAGTGGCTG AGAGAAGAGA CAGACCAGGT GCTGGAAAGG GGGCCTGTGC 1200
TTCAGTTGCA TGACCTGAAA CGGGAGGCAG GAGGCGGCTA TCGCTGCGTG GCGTCTGTGC 1260
CCAGCATACC CGGCCTGAAC CGCACACAGC TGGTCAAGCT GGCCATTTTT GGCCCCCCTT 1320
GGATGGCATT CAAGGAGAGG AAGGTGTGGG TGAAAGAGAA TATGGTGTTG AATCTGTCTT 1380
GTGAAGCGTC AGGGCACCCC CGGCCCACCA TCTCCTGGAA CGTCAACGGC ACGGCAAGTG 1440 0 AACAAGACCA AGATCCACAG CGAGTCCTGA GCACCCTGAA TGTCCTCGTG ACCCCGGAGC 1500
TGTTGGAGAC AGGTGTTGAA TGCACGGCCT CCAACGACCT CGGCAAAAAC ACCAGCATCC 1560
TCTTCCTGGA GCTGGTCAAT TTAACCACCC TCACACCAGA CTCCAACACA ACCACTGGCC 1620
TCAGCACTTC CACTGCCAGT CCTCATACCA GAGCCAACAG CACCTCCACA GAGAGAAAGC 1680
TGCCGGAGCC GGAGAGCCGG GGCGTGGTCA TCGTGGCTGT GATTGTGTGC ATCCTGGTCC 1740 5 TGGCGGTGCT GGGCGCTGTC CTCTATTTCC TCTATAAGAA GGGCAAGCTG CCGTGCAGGC 1800
GCTCAGGGAA GCAGGAGATC ACGCTGCCCC CGTCTCGTAA GACCGAACTT GTAGTTGAAG 1860
TTAAGTCAGA TAAGCTCCCA GAAGAGATGG GCCTCCTGCA GGGCAGCAGC GGTGACAAGA 1920
GGGCTCCGGG AGACCAGGGA GAGAAATACA TCGATCTGAG GCATTAGCCC CGAATCACTT 1980
CAGCTCCCTT CCCTGCCTGG ACCATTCCCA GCTCCCTGCT CACTCTTCTC TCAGCCAAAG 2040 0 CCTCCAAAGG GACTAGAGAG AAGCCTCCTG CTCCCCTCAC CTGCACACCC CCTTTCAGAG 2100
GGCCACTGGG TTAGGACCTG AGGACCTCAC TTGGCCCTGC AAGCCGCTTT TCAGGGACCA 2160
GTCCACCACC ATCTCCTCCA CGTTGAGTGA AGCTCATCCC AAGCAAGGAG CCCCAGTCTC 2220
CCGAGCGGGT AGGAGAGTTT CTTGCAGAAC GTGTTTTTTC TTTACACACA TTATGGCTGT 2280
AAATACCTGG CTCCTGCCAG CAGCTGAGCT GGGTAGCCTC TCTGAGCTGG TTTCCTGCCC 2340 5 CAAAGGCTGG CTTCCACCAT CCAGGTGCAC CACTGAAGTG AGGACACACC GGAGCCAGGC 2400
GCCTGCTCAT GTTGAAGTGC GCTGTTCACA CCCGCTCCGG AGAGCACCCC AGCGGCATCC 2460
AGAAGCAGCT GCAGTGTTGC TGCCACCACC CTCCTGCTCG CCTCTTCAAA GTCTCCTGTG 2520
ACATTTTTTC TTTGGTCAGA AGCCAGGAAC TGGTGTCATT CCTTAAAAGA TACGTGCCGG 2580
GGCCAGGTGT GGTGGCTCAC GCCTGTAATC CCAGCACTTT GGGAGGCCGA GGCGGGCGGA 2640 0 TCACAAAGTC AGGACGAGAC CATCCTGGCT AACACGGTGA AACCCTGTCT CTACTAAAAA 2700
TACAAAAAAA AATTAGCTAG GCGTAGTGGT TGGCACCTAT AGTCCCAGCT ACTCGGAAGG 2760
CTGAAGCAGG AGAATGGTAT GAATCCAGGA GGTGGAGCTT GCAGTGAGCC GAGACCGTGC 2820
CACTGCACTC CAGCCTGGGC AACACAGCGA GACTCCGTCT CGAGGAAAAA AAAAGAAAAG 2880
ACGCGTACCT GCGGTGAGGA AGCTGGGCGC TGTTTTCGAG TTCAGGTGAA TTAGCCTCAA 2940 5 TCCCCGTGTT CACTTGCTCC CATAGCCCTC TTGATGGATC ACGTAAAACT GAAAGGCAGC 3000
GGGGAGCAGA CAAAGATGAG GTCTACACTG TCCTTCATGG GGATTAAAGC TATGGTTATA 3060
TTAGCACCAA ACTTCTACAA ACCAAGCTCA GGGCCCCAAC CCTAGAAGGG CCCAAATGAG 3120
AGAATGGTAC TTAGGGATGG AAAACGGGGC CTGGCTAGAG CTTCGGGTGT GTGTGTCTGT 3180
CTGTGTGTAT GCATACATAT GTGTGTATAT ATGGTTTTGT CAGGTGTGTA AATTTGCAAA 3240 0 TTGTTTCCTT TATATATGTA TGTATATATA TATATGAAAA TATATATATA TATGAAAAAT 3300
AAAGCTTAAT TGTCCCAGAA AATCATACAT TGCTTTTTTA TTCTACATGG GTACCACAGG 3360
AACCTGGGGG CCTGTGAAAC TACAACCAAA AGGCACACAA AACCGTTTCC AGTTGGCAGC 3420
AGAGATCAGG GGTTACCTCT GCTTCTGAGC AAATGGCTCA AGCTCTACCA GAGCAGACAG 3480
CTACCCTACT TTTCAGCAGC AAAACGTCCC GTATGACGCA GCACGAAGGG CCTGGCAGGC 3540 5 TGTTAGCAGG AGCTATGTCC CTTCCTATCG TTTCCGTCCA CTT
Seq ID NO: 352 Protein sequence Protein Accession ft: NP 006491.1 0 11 21 31 41 51
GLPRLVCAFL LAACCCCPRV AGVPGEAEQP APELVEVEVG STALLKCGLS QSQGNLSHVD 60 WFSVHKEKRT LIFRVRQGQG QSEPGEYEQR LSLQDRGATL ALTQVTPQDE RIFLCQGKRP 120 RSQEYRIQLR VYKAPEEPNI QVNPLGIPVN SKEPEEVATC VGRNGYPIPQ VIWYKNGRPL 180 5 KEEKNRVHIQ SSQTVESSGL YTLQSILKAQ LVKEDKDAQF YCELNYRLPS GNHMKESREV 240 TVPVFYPTEK VWLEVEPVGM LKEGDRVEIR CLADGNPPPH FSISKQNPST REAEEETTND 300 NGVLVLEPAR KEHSGRYECQ AWNLDTMISL LSEPQELLVN YVSDVRVSPA APERQEGSSL 360 TLTCEAESSQ DLEFQWLREE TDQVLERGPV LQLHDLKREA GGGYRCVASV PSIPGLNRTQ 420 LVKLAIFGPP WMAFKERKVW VKENMVLNLS CEASGHPRPT ISWNVNGTAS EQDQDPQRVL 480 0 STLNVLVTPE LLETGVECTA SNDLGKNTSI LFLELVNLTT LTPDSNTTTG LSTSTASPHT 540 RANSTSTERK LPEPESRGW IVAVIVCILV LAVLGAVLYF LYKKGKLPCR RSGKQEITLP 600 PSRKTELWE VKSDKLPEEM GLLQGSSGDK RAPGDQGEKY IDLRH
Seq ID NO: 353 DNA sequence I D Nucleic Acid Accession ft: NM_003183.3
Coding sequence: 165..2639
11 21 31 41 51
I I I I I 0 TCGAGCCTGG CGGTAGAATC TTCCCAGTAG GCGGCGCGGG AGGGAAAAGA GGATTGAGGG 60 GCTAGGCCGG GCGGATCCCG TCCTCCCCCG ATGTGAGCAG TTTTCCGAAA CCCCGTCAGG 120 CGAAGGCTGC CCAGAGAGGT GGAGTCGGTA GCGGGGCCGG GAACATGAGG CAGTCTCTCC 180 TATTCCTGAC CAGCGTGGTT CCTTTCGTGC TGGCGCCGCG ACCTCCGGAT GACCCGGGCT 240 TCGGCCCCCA CCAGAGACTC GAGAAGCTTG ATTCTTTGCT CTCAGACTAC GATATTCTCT 300 CTTTATCTAA TATCCAGCAG CATTCGGTAA GAAAAAGAGA TCTACAGACT TCAACACATG 360
TAGAAACACT ACTAACTTTT TCAGCTTTGA AAAGGCATTT TAAATTATAC CTGACATCAA 420
GTACTGAACG TTTTTCACAA AATTTCAAGG TCGTGGTGGT GGATGGTAAA AACGAAAGCG 480
AGTACACTGC AAAATGGCAG GACTTCTTCA CTGGACACGT GGTTGGTGAG CCTGACTCTA 540
GGGTTCTAGC CCACATAAGA GATGATGATG TTATAATCAG AATCAACACA GATGGGGCCG 600
AATATAACAT AGAGCCACTT TGGAGATTTG TTAATGATAC CAAAGACAAA AGAATGTTAG 660
TTTATAAATC TGAAGATATC AAGAATGTTT CACGTTTGCA GTCTCCAAAA GTGTGTGGTT 720
ATTTAAAAGT GGATAATGAA GAGTTGCTCC CAAAAGGGTT AGTAGACAGA GAACCACCTG 780
AAGAGCTTGT TCATCGAGTG AAAAGAAGAG CTGACCCAGA TCCCATGAAG AACACGTGTA 840
AATTATTGGT GGTAGCAGAT CATCGCTTCT ACAGATACAT GGGCAGAGGG GAAGAGAGTA 900
CAACTACAAA TTACTTAATA GAGCTAATTG ACAGAGTTGA TGACATCTAT CGGAACACTT 960
CATGGGATAA TGCAGGTTTT AAAGGCTATG GAATACAGAT AGAGCAGATT CGCATTCTCA 1020
AGTCTCCACA AGAGGTAAAA CCTGGTGAAA AGCACTACAA CATGGCAAAA AGTTACCCAA 1080
ATGAAGAAAA GGATGCTTGG GATGTGAAGA TGTTGCTAGA GCAATTTAGC TTTGATATAG 1140
CTGAGGAAGC ATCTAAAGTT TGCTTGGCAC ACCTTTTCAC ATACCAAGAT TTTGATATGG 1200
GAACTCTTGG ATTAGCTTAT GTTGGCTCTC CCAGAGCAAA CAGCCATGGA GGTGTTTGTC 1260
CAAAGGCTTA TTATAGCCCA GTTGGGAAGA AAAATATCTA TTTGAATAGT GGTTTGACGA 1320
GCACAAAGAA TTATGGTAAA ACCATCCTTA CAAAGGAAGC TGACCTGGTT ACAACTCATG 1380
AATTGGGACA TAATTTTGGA GCAGAACATG ATCCGGATGG TCTAGCAGAA TGTGCCCCGA 1440
ATGAGGACCA GGGAGGGAAA TATGTCATGT ATCCCATAGC TGTGAGTGGC GATCACGAGA 1500
ACAATAAGAT GTTTTCAAAC TGCAGTAAAC AATCAATCTA TAAGACCATT GAAAGTAAGG 1560
CCCAGGAGTG TTTTCAAGAA CGCAGCAATA AAGTTTGTGG GAACTCGAGG GTGGATGAAG 1620
GAGAAGAGTG TGATCCTGGC ATCATGTATC TGAACAACGA CACCTGCTGC AACAGCGACT 1680
GCACGTTGAA GGAAGGTGTC CAGTGCAGTG ACAGGAACAG TCCTTGCTGT AAAAACTGTC 1740
AGTTTGAGAC TGCCCAGAAG AAGTGCCAGG AGGCGATTAA TGCTACTTGC AAAGGCGTGT 1800
CCTACTGCAC AGGTAATAGC AGTGAGTGCC CGCCTCCAGG AAATGCTGAA AATGACACTG 1860
TTTGCTTGGA TCTTGGCAAG TGTAAGGATG GGAAATGCAT CCCTTTCTGC GAGAGGGAAC 1920
AGCAGCTGGA GTCCTGTGCA TGTAATGAAA CTGACAACTC CTGCAAGGTG TGCTGCAGGG 1980
ACCTTTCTGG CCGCTGTGTG CCCTATGTCG ATGCTGAACA AAAGAACTTA TTTTTGAGGA 2040
AAGGAAAGCC CTGTACAGTA GGATTTTGTG ACATGAATGG CAAATGTGAG AAACGAGTAC 2100
AGGATGTAAT TGAACGATTT TGGGATTTCA TTGACCAGCT GAGCATCAAT ACTTTTGGAA 2160
AGTTTTTAGC AGACAACATC GTTGGGTCTG TCCTGGTTTT CTCCTTGATA TTTTGGATTC 2220
CTTTCAGCAT TCTTGTCCAT TGTGTGGATA AGAAATTGGA TAAACAGTAT GAATCTCTGT 2280
CTCTGTTTCA CCCCAGTAAC GTCGAAATGC TGAGCAGCAT GGATTCTGCA TCGGTTCGCA 2340
TTATCAAACC CTTTCCTGCG CCCCAGACTC CAGGCCGCCT GCAGCCTGCC CCTGTGATCC 2400
CTTCGGCGCC AGCAGCTCCA AAACTGGACC ACCAGAGAAT GGACACCATC CAGGAAGACC 2460
CCAGCACAGA CTCCCATATG GACGAGGATG GGTTTGAGAA GGACCCCTTC CCAAATAGCA 2520
GCACAGCTGC CAAGTCATTT GAGGATCTCA CGGACCATCC GGTCGCCAGA AGTGAAAAGG 2580
CTGCCTCCTT TAAACTGCAG CGTCAGAATC GTGTTAACAG CAAAGAAACA GAGTGCTAAT 2640
TTAGTTCTCA GCTCTTCTGA CTTAAGTGTG CAAAATATTT TTATAGATTT GACCTACAAA 2700
TCAATCACAG CTTGTATTTT GTGAAGACTG GGAAGTGACT TAGCAGATGC TGGTCATGTG 2760
TTTGAACTTC CTGCAGGTAA ACAGTTCTTG TGTGGTTTGG CCCTTCTCCT TTTGAAAAGG 2820
TAAGβTGAAA GTGAATCTAC TTATTTTGAG GCTTTCAGGT TTTAGTTTTT AAAATATCTT 2880
TTGACCTGTG GTGCAAAAGC AGAAAATACA GCTGGATTGG GTTATGAATA TTTACGTTTT 2940
TGTAAATTAA TCTTTTATAT TGATAACAGC ACTGACTAGG GAAATGATCA GTTTTTTTTT 3000
ATACACTGTA ATGAACCGCT GAATATGAAG CATTTGGCAT TTATTTGTGA GAAAAGTGGA 3060
ATAGTTTTTT TTTTTTTTTT TTTTTTTTGC CTTCAACTAA AAACAAAGGA GATAAATTTA 3120
GTATACATTG TATCTAAATT GTGGGTCTAT TTCTAGTTAT TACCCAGAGT TTTTATGTAG 3180
CAGGGAAAAT ATATATCTAA ATTTAGAAAT CATTTGGGTT AATATGGCTC TTCATAATTC 3240
TAAGACTAAT GCTCAGAACC TAACCACTAC CTTACAGTGA GGGCTATACA TGGTAGCCAG 3300
TTGAATTTAT GGAATCTACC AACTGTTTAG GGCCCTGATT TGCTGGGCAG TTTTTCTGTA 3360
TTTTATAAGT ATCTTCATGT ATCCCTGTTA CTGATAGGGA TACATGTCTT AGAAAATTCA 3420
CTATTGGCTG GGAGTGGTGG CTCATGCCTG TAATCCCAGC ACTTGGAGAG GCTGAGGTTG 3480
CGCCACTACA CTCCAGCCTG GGTGACAGAG TGAGATCTGC CTC
Seq ID NO: 354 Protein sequence Protein Accession #: NP_003174.2 1 11 21 31 41 51 i i i i i i
MRQSLLFLTS WPFVLAPRP PDDPGFGPHQ RLEKLDSLLS DYDILSLSNI QQHSVRKRDL 60
QTSTHVETLL TFSALKRHFK LYLTSSTERF SQNFKW D GKNESEYTAK WQDFFTGHW 120
GEPDSRVLAH IRDDDVIIRI NTDGAEYNIE PLWRFVNDTK DKRMLVYKSE DIKNVSRLQS 180
PKVCGYLKVD NEELLPKGLV DREPPEELVH RVKRRADPDP MKNTCKLLW ADHRFYRYMG 240 RGEESTTTNY LIELIDRVDD lYRNTSWDNA GFKGYGIQIE QIRILKSPQE VKPGEKHYNM 300
AKSYPNEEKD AWDVKMLLEQ FSFDIAEEAS KVCLAHLFTY QDFDMGTLGL AYVGSPRANS 360
HGGVCPKAYY SPVGKKKIYL NSGLTSTKNY GKTILTKEAD LVTTHELGHN FGAEHDPDGL 420
AECAPNEDQG GKYVMYPIAV SGDHENNKMF SNCSKQSIYK TIESKAQECF QERSNKVCGN 480
SRVDEGEECD PGIMYLNNDT CCNSDCTLKE GVQCSDRNSP CCKNCQFETA QKKCQEAINA 540 TCKGVSYCTG NSSECPPPGN AENDTVCLDL GKCKDGKCIP FCEREQQLES CACNETDNSC 600
KVCCRDLSGR CVPYVDAEQK NLFLRKGKPC TVGFCDMNGK CEKRVQDVIE RFWDFIDQLS 660
INTFGKFLAD NIVGSVLVFS LIFWIPFSIL VHCVDK LDK QYESLSLFHP SNVEMLSSMD 720
SASVRIIKPF PAPQTPGRLQ PAPVIPSAPA APKLDHQRMD TIQEDPSTDS HMDEDGFEKD 780 PFPNSSTAAK SFEDLTDHPV ARSEKAASFK LQRQNRVNSK ETEC
Seq ID NO : 355 DNA sequence
Nucleic Acid Accession # : NM_021832 . 1
Coding sequence : 164 . .2248
1 11 21 31 41 51
I I I I I I
TCGAGCCTGG CGGTAGAATC TTCCCAGTAG GCGGCGCGGG AGGAAAAGAG GATTGAGGGG 60
CTAGGCCGGG CGGATCCCGT CCTCCCCCGA TGTGAGCAGT TTTCCGAAAC CCCGTCAGGC 120 GAAGGCTGCC CAGAGAGGTG GAGTCGGTAG CGGGGCCGGG AACATGAGGC AGTCTCTCCT 180 ATTCCTGACC AGCGTGGTTC CTTTCGTGCT GGCGCCGCGA CCTCCGGATG ACCCGGGCTT 240
CGGCCCCCAC CAGAGACTCG AGAAGCTTGA TTCTTTGCTC TCAGACTACG ATATTCTCTC 300
TTTATCTAAT ATCCAGCAGC ATTCGGTAAG AAAAAGAGAT CTACAGACTT CAACACATGT 360
AGAAACACTA CTAACTTTTT CAGCTTTGAA AAβGCATTTT AAATTATACC TGACATCAAG 420
TACTGAACGT TTTTCACAAA ATTTCAAGGT CGTGGTGGTG GATGGTAAAA ACGAAAGCGA 480
GTACACTGTA AAATGGCAGG ACTTCTTCAC TGGACACGTG GTTGGTGAGC CTGACTCTAG 540
GGTTCTAGCC CACATAAGAG ATGATGATGT TATAATCAGA ATCAACACAG ATGGGGCCGA 600
ATATAACATA GAGCCACTTT GGAGATTTGT TAATGATACC AAAGACAAAA GAATGTTAGT 660
TTATAAATCT GAAGATATCA AGAATGTTTC ACGTTTGCAG TCTCCAAAAG TGTGTGGTTA 720
TTTAAAAGTG GATAATGAAG AGTTGCTCCC AAAAGGGTTA GTAGACAGAG AACCACCTGA 780
AGAGCTTGTT CATCGAGTGA AAAGAAGAGC TGACCCAGAT CCCATGAAGA ACACGTGTAA 840
ATTATTGGTG GTAGCAGATC ATCGCTTCTA CAGATACATG GGCAGAGGGG AAGAGAGTAC 900
AACTACAAAT TACTTAATAG AGCTAATTGA CAGAGTTGAT GACATCTATC GGAACACTTC 960
ATGGGATAAT GCAGGTTTTA AAGGCTATGG AATACAGATA GAGCAGATTC GCATTCTCAA 1020
GTCTCCACAA GAGGTAAAAC CTGGTGAAAA GCACTACAAC ATGGCAAAAA GTTACCCAAA 1080
TGAAGAAAAG GATGCTTGGG ATGTGAAGAT GTTGCTAGAG CAATTTAGCT TTGATATAGC 1140
TGAGGAAGCA TCTAAAGTTT GCTTGGCACA CCTTTTCACA TACCAAGATT TTOATATGGG 1200
AACTCTTGGA TTAGCTTATG TTGGCTCTCC CAGAGCAAAC AGCCATGGAG GTGTTTGTCC 1260
AAAGGCTTAT TATAGCCCAG TTGGGAAGAA AAATATCTAT TTGAATAGTG GTTTGACGAG 1320
CACAAAGAAT TATGGTAAAA CCATCCTTAC AAAGGAAGCT GACCTGGTTA CAACTCATGA 1380
ATTGGGACAT AATTTTGGAG CAGAACATGA TCCGGATGGT CTAGCAGAAT GTGCCCCGAA 1440
TGAGGACCAG GGAGGGAAAT ATGTCATGTA TCCCATAGCT GTGAGTGGCG ATCACGAGAA 1500
CAATAAGATG TTTTCAAACT GCAGTAAACA ATCAATCTAT AAGACCATTG AAAGTAAGGC 1560
CCAGGAGTGT TTTCAAGAAC GCAGCAATAA AGTTTGTGGG AACTCGAGGG TGGATGAAGG 1620
AGAAGAGTGT GATCCTGGCA TCATGTATCT GAACAACGAC ACCTGCTGCA ACAGCGACTG 1680
CACGTTGAAG GAAGGTGTCC AGTGCAGTGA CAGGAACAGT CCTTGCTGTA AAAACTGTCA 1740
GTTTGAGACT GCCCAGAAGA AGTGCCAGGA GGCGATTAAT GCTACTTGCA AAGGCGTGTC 1800
CTACTGCACA GGTAATAGCA GTGAGTGCCC GCCTCCAGGA AATGCTGAAG ATGACACTGT 1860
TTGCTTGGAT CTTGGCAAGT GTAAGGATGG GAAATGCATC CCTTTCTGCG AGAGGGAACA 1920
GCAGCTGGAG TCCTGTGCAT GTAATGAAAC TGACAACTCC TGCAAGGTGT GCTGCAGGGA 1980
CCTTTCCGGC CGCTGTGTGC CCTATGTCGA TGCTGAACAA AAGAACTTAT TTTTGAGGAA 2040
AGGAAAGCCC TGTACAGTAG GATTTTGTGA CATGAATGGC AAATGTGAGA AACGAGTACA 2100
GGATGTAATT GAACGATTTT GGGATTTCAT TGACCAGCTG AGCATCAATA CTTTTGGAAA 2160
GTTTTTAGCA GACAACATCG TTGGGTCTGT CCTGGTTTTC TCCTTGATAT TTTGGATTCC 2220
TTTCAGCATT CTTGTCCATT GTGTGTAACG TCGAAATGCT GAGCAGCATG GATTCTGCAT 2280
CGGTTCGCAT TATCAAACCC TTTCCTGCGC CCCAGACTCC AGGCCGCCTG CAGCCTGCCC 2340
CTGTGATCCC TTCGGCGCCA GCAGCTCCAA AACTGGACCA CCAGAGAATG GACACCATCC 2400
AGGAAGACCC CAGCACAGAC TCACATATGG ACGAGGATGG GTTTGAGAAG GACCCCTTCC 2460
CAAATAGCAG CACAGCTGCC AAGTCATTTG AGGATCTCAC GGACCATCCG GTCACCAGAA 2520
GTGAAAAGGC TGCCTCCTTT AAACTGCAGC GTCAGAATCG TGTTGACAGC AAAGAAACAG 2580
AGTGCTAATT TAGTTCTCAG CTCTTCTGAC TTAAGTGTGC AAAATATTTT TATAGATTTG 2640
ACCTACAATC AATCACAGCT TATATTTTGT GAAGACTGGG AAGTGACTTA GCAGATGCTG 2700
GTCATGTGTT TGAACTTCCT GCAGGTAAAC AGTTCTTGTG TGGTTTGGCC CTTCTCCTTT 2760
TGAAAAGGTA AGGTGAAGGT GAATCTAGCT TATTTTGAGG CTTTCAGGTT TTAGTTTTTA 2820
AAATATCTTT TGACCTGTGG TGCAAAAGCA GAAAATACAG CTGGATTGGG TTATGAGTAT 2880
TTACGTTTTT GTAAATTAAT CTTTTATATT GATAACAGGC ACTGACTAGG GAAATGATCA 2940
GTTTTTTTTT ATACACTGTA ATGAACCGCT GAATATGAAG CATTTGGCAT TTATTTGTGA 3000
GAAAAGTGGA ATAGTTTTTT TTTTTTTTTT TTTTTTTTGC CTTCAACTAA AAACAAAGGA 3060
GATAAATTTA GTATACATTG TATCTAAATT GTGGGTCTAT TTCTAGTTAT TACCCAGAGT 3120
TTTTATGTAG CAGGGAAAAT ATATATCTAA ATTTAGAAAT CATTTGGGTT AATATGGCTC 3180
TTCATAATTC TAAGACTAAT GCTCAGAACC TAACCACTAC CTTACAGTGA GGGCTATACA 3240
TGGTAGCCAG TTGAATTTAT GGAATCTACC AACTGTTTAG GGCCCTGATT TGCTGGGCAG 3300
TTTTTCTGTA TTTTATAAGT ATCTTCATGT ATCCCTGTTA CTGATAGGGA TACATGTCTT 3360
AGAAAATTCA CTATTGGCTG GGAGTGGTGG CTCATGCCTG TAATCCCAGC ACTTGGAGAG 3420
3421 GCTGAGGTTG CGCCACTACA CTCCAGCCTG GGTGACAGAG TGAGATCTGC CTC
Seq ID NO: 356 Protein sequence Protein Accesεion it: NP 068604.1
11 21 31 41 51
I I I I I I
MRQSLLFLTS WPFVLAPRP PDDPGFGPHQ RLEKLDSLLS DYDILSLSNI QQHSVRKRDL 60 QTSTHVETLL TPSALKRHFK LYLTSSTERF SQNFK WD GKNESEYTVK WQDFFTGHW 120 GEPDSRVLAH IRDDDVIIRI NTDGAEYNIE PLWRFVNDTK DKRMLVYKSE DIKNVSRLQS 180 PKVCGYLKVD NEELLPKGLV DREPPEELVH RVKRRADPDP MKNTCKLLW ADHRFYRYMG 240 RGEESTTTNY L1ELIDRVDD IYRNTSWDNA GFKGYGIQIE QIRILKSPQE VKPGEKHYNM 300 AKSYPNEEKD AWDVKMLLEQ FSFDIAEEAS KVCLAHLFTY QDFDMGTLGL AYVGSPRANS 360 HGGVCPKAYY SPVGKKNIYL NSGLTSTKNY GKTILTKEAD LVTTHELGHN FGAEHDPDGL 420 AECAPNEDQG GKYVMYPIAV SGDHENNKMF SNCSKQSIYK TIESKAQECF QERSNKVCGN 480 SRVDEGEECD PGIMYLNNDT CCNSDCTLKE GVQCSDRNSP CCKNCQFETA QKKCQEAINA 540 TCKGVSYCTG NSSECPPPGN AEDDTVCLDL GKCKDGKCIP FCEREQQLES CACNETDNSC 600 KVCCRDLSGR CVPYVDAEQK NLFLRKGKPC TVGFCDMNGK CEKRVQDVIE RFWDFIDQLS 660 INTFGKFLAD NIVGSVLVFS LIFWIPFSIL VHCV
Seq ID NO: 357 DNA sequence
Nucleic Acid Acceεεion ft: NM_004994.1
Coding εequence: 20..2143
1 11 21 31 41 51
I I I I I I
AGACACCTCT GCCCTCACCA TGAGCCTCTG GCAGCCCCTG GTCCTGGTGC TCCTGGTGCT 60
GGGCTGCTGC TTTGCTGCCC CCAGACAGCG CCAGTCCACC CTTGTGCTCT TCCCTGGAGA 120
CCTGAGAACC AATCTCACCG ACAGGCAGCT GGCAGAGGAA TACCTGTACC GCTATGGTTA 180
CACTCGGGTG GCAGAGATGC GTGGAGAGTC GAAATCTCTG GGGCCTGCGC TGCTGCTTCT 240 CCAGAAGCAA CTGTCCCTGC CCGAGACCGG TGAGCTGGAT AGCGCCACGC TGAAGGCCAT 300 GCGAACCCCA CGGTGCGGGG TCCCAGACCT GGGCAGATTC CAAACCTTTG AGGGCGACCT 360 CAAGTGGCAC CACCACAACA TCACCTATTG GATCCAAAAC TACTCGGAAG ACTTGCCGCG 420 GGCGGTGATT GACGACGCCT TTGCCCGCGC CTTCGCACTG TGGAGCGCGG TGACGCCGCT 480 CACCTTCACT CGCGTGTACA GCCGGGACGC AGACATCGTC ATCCAGTTTG GTGTCGCGGA 540 GCACGGAGAC GGGTATCCCT TCGACGGGAA GGACGGGCTC CTGGCACACG CCTTTCCTCC 600 TGGCCCCGGC ATTCAGGGAG ACGCCCATTT CGACGATGAC GAGTTGTGGT CCCTGGGCAA 660 GGGCGTCGTG GTTCCAACTC GGTTTGGAAA CGCAGATGGC GCGGCCTGCC ACTTCCCCTT 720 CATCTTCGAG GGCCGCTCCT ACTCTGCCTG CACCACCGAC GGTCGCTCCG ACGGCTTGCC 780 CTGGTGCAGT ACCACGGCCA ACTACGACAC CGACGACCGG TTTGGCTTCT GCCCCAGCGA 840 GAGACTCTAC ACCCGGGACG GCAATGCTGA TGGGAAACCC TGCCAGTTTC CATTCATCTT 900 CCAAGGCCAA TCCTACTCCG CCTGCACCAC GGACGGTCGC TCCGACGGCT ACCGCTGGTG 960 CGCCACCACC GCCAACTACG ACCGGGACAA GCTCTTCGGC TTCTGCCCGA CCCGAGCTGA 1020 CTCGACGGTG ATGGGGGGCA ACTCGGCGGG GGAGCTGTGC GTCTTCCCCT TCACTTTCCT 1080 GGGTAAGGAG TACTCGACCT GTACCAGCGA GGGCCGCGGA GATGGGCGCC TCTGGTGCGC 1140 TACCACCTCG AACTTTGACA GCGACAAGAA GTGGGGCTTC TGCCCGGACC AAGGATACAG 1200 TTTGTTCCTC GTGGCGGCGC ATGAGTTCGG CCACGCGCTG GGCTTAGATC ATTCCTCAGT 1260 GCCGGAGGCG CTCATGTACC CTATGTACCG CTTCACTGAG GGGCCCCCCT TGCATAAGGA 1320 CGACGTGAAT GGCATCCGGC ACCTCTATGG TCCTCGCCCT GAACCTGAGC CACGGCCTCC 1380 AACCACCACC ACACCGCAGC CCACGGCTCC CCCGACGGTC TGCCCCACCG GACCCCCCAC 1440 TGTCCACCCC TCAGAGCGCC CCACAGCTGG CCCCACAGGT CCCCCCTCAG CTGGCCCCAC 1500 AGGTCCCCCC ACTGCTGGCC CTTCTACGGC CACTACTGTG CCTTTGAGTC CGGTGGACGA 1560 TGCCTGCAAC GTGAACATCT TCGACGCCAT CGCGGAGATT GGGAACCAGC TGTATTTGTT 1620 CAAGGATGGG AAGTACTGGC GATTCTCTGA GGGCAGGGGG AGCCGGCCGC AGGGCCCCTT 1680 CCTTATCGCC GACAAGTGGC CCGCGCTGCC CCGCAAGCTG GACTCGGTCT TTGAGGAGCC 1740 GCTCTCCAAG AAGCTTTTCT TCTTCTCTGG GCGCCAGGTG TGGGTGTACA CAGGCGCGTC 1800 GGTGCTGGGC CCGAGGCGTC TGGACAAGCT GGGCCTGGGA GCCGACGTGG CCCAGGTGAC 1860 CGGGGCCCTC CGGAGTGGCA GGGGGAAGAT GCTGCTGTTC AGCGGGCGGC GCCTCTGGAG 1920 GTTCGACGTG AAGGCGCAGA TGGTGGATCC CCGGAGCGCC AGCGAGGTGG ACCGGATGTT 1980 CCCCGGGGTG CCTTTGGACA CGCACGACGT CTTCCAGTAC CGAGAGAAAG CCTATTTCTG 2040 CCAGGACCGC TTCTACTGGC GCGTGAGTTC CCGGAGTGAG TTGAACCAGG TGGACCAAGT 2100 GGGCTACGTG ACCTATGACA TCCTGCAGTG CCCTGAGGAC TAGGGCTCCC GTCCTGCTTT 2160 GCAGTGCCAT GTAAATCCCC ACTGGGACCA ACCCTGGGGA AGGAGCCAGT TTGCCGGATA 2220 CAAACTGGTA TTCTGTTCTG GAGGAAAGGG AGGAGTGGAG GTGGGCTGGG CCCTCTCTTC 2280 TCACCTTTGT TTTTTGTTGG AGTGTTTCTA ATAAACTTGG ATTCTCTAAC CTTT
Seq ID NO: 358 Protein sequence Protein Accession ft: NP 004985.1
11 21 31 41 51
MSLWQPLVLV LLVLGCCFAA PRQRQSTLVL FPGDLRTNLT DRQLAEEYLY RYGYTRVAEM 60 RGESKSLGPA LLLLQKQLSL PETGELDSAT LKAMRTPRCG VPDLGRFQTF EGDLKWHHHN 120 ITYWIQNYSE DLPRAVIDDA FARAFALWSA VTPLTFTRVY SRDADIVIQF GVAEHGDGYP 180 FDGKDGLLAH AFPPGPGIQG DAHFDDDELW SLGKG VPT RFGNADGAAC HFPFIFEGRS 240 YSACTTDGRS DGLPWCSTTA NYDTDDRFGF CPSERLYTRD GNADGKPCQF PFIFQGQSYS 300 ACTTDGRSDG YRWCATTANY DRDKLFGFCP TRADSTVMGG NSAGELCVFP FTFLGKEYST 360 CTSEGRGDGR LWCATTSNFD SDKKWGFCPD QGYSLFLVAA HEFGHALGLD HSSVPEALMY 420 PMYRFTEGPP LHKDDVNGIR HLYGPRPEPE PRPPTTTTPQ PTAPPTVCPT GPPTVHPSER 480 PTAGPTGPPS AGPTGPPTAG PSTATTVPLS PVDDACNVNI FDAIAEIGNQ LYLFKDGKYW 540 RFSEGRGSRP QGPFLIADKW PALPRKLDSV FEEPLSKKLF FFSGRQVWVY TGASVLGPRR 600 LDKLGLGADV AQVTGALRSG RGKMLLFSGR RLWRFDVKAQ MVDPRSASEV DRMFPGVPLD 660 THDVFQYREK AYFCQDRFYW RVSSRSELNQ VDQVGYVTYD ILQCPED
Seq ID NO: 359 DNA sequence
Nucleic Acid Accession #: NM_000213.1
Coding sequence: 127..5385
1 11 21 31 41 51 1 1 | 1 | 1 | 1 | 1 1 1 CGCCCGCGCG CTGCAGCCCC ATCTCCTAGC GGCAGCCCAG GCGCGGAGGG AGCGAGTCCG 60
CCCCGAGGTA GGTCCAGGAC GGGCGCACAG CAGCAGCCGA GGCTGGCCGG GAGAGGGAGG 120
AAGAGGATGG CAGGGCCACG CCCCAGCCCA TGGGCCAGGC TGCTCCTGGC AGCCTTGATC 180
AGCGTCAGCC TCTCTGGGAC CTTGGCAAAC CGCTGCAAGA AGGCCCCACT GAAGAGCTGC 240
ACGGAGTGTG TCCGTGTGGA TAAGGACTGC GCCTACTGCA CAGACGAGAT GTTCAGGGAC 300
CGGCGCTGCA ACACCCAGGC GGAGCTGCTG GCCGCGGGCT GCCAGCGGGA GAGCATCGTG 360
GTCATGGAGA GCAGCTTCCA AATCACAGAG GAGACCCAGA TTGACACCAC CCTGCGGCGC 420
AGCCAGATGT CCCCCCAAGG CCTGCGGGTC CGTCTGCGGC CCGGTGAGGA GCGGCATTTT 480
GAGCTGGAGG TGTTTGAGCC ACTGGAGAGC CCCGTGGACC TGTACATCCT CATGGACTTC 540
TCCAACTCCA TGTCCGATGA TCTGGACAAC CTCAAGAAGA TGGGGCAGAA CCTGGCTCGG 600
GTCCTGAGCC AGCTCACCAG CGACTACACT ATTGGATTTG GCAAGTTTGT GGACAAAGTC 660
AGCGTCCCGC AGACGGACAT GAGGCCTGAG AAGCTGAAGG AGCCCTGGCC CAACAGTGAC 720
CCCCCCTTCT CCTTCAAGAA CGTCATCAGC CTGACAGAAG ATGTGGATGA GTTCCGGAAT 780
AAACTGCAGG GAGAGCGGAT CTCAGGCAAC CTGGATGCTC CTGAGGGCGG CTTCGATGCC 840
ATCCTGCAGA CAGCTGTGTG CACGAGGGAC ATTGGCTGGC GCCCGGACAG CACCCACCTG 900
CTGGTCTTCT CCACCGAGTC AGCCTTCCAC TATGAGGCTG ATGGCGCCAA CGTGCTGGCT 960
GGCATCATGA GCCGCAACGA TGAACGGTGC CACCTGGACA CCACGGGCAC CTACACCCAG 1020
TACAGGACAC AGGACTACCC GTCGGTGCCC ACCCTGGTGC GCCTGCTCGC CAAGCACAAC 1080
ATCATCCCCA TCTTTGCTGT CACCAACTAC TCCTATAGCT ACTACGAGAA GCTTCACACC 1140
TATTTCCCTG TCTCCTCACT GGGGGTGCTG CAGGAGGACT CGTCCAACAT CGTGGAGCTG 1200
CTGGAGGAGG CCTTCAATCG GATCCGCTCC AACCTGGACA TCCGGGCCCT AGACAGCCCC 1260
CGAGGCCTTC GGACAGAGGT CACCTCCAAG ATGTTCCAGA AGACGAGGAC TGGGTCCTTT 1320
CACATCCGGC GGGGGGAAGT GGGTATATAC CAGGTGCAGC TGCGGGCCCT TGAGCACGTG 1380
GATGGGACGC ACGTGTGCCA GCTGCCGGAG GACCAGAAGG GCAACATCCA TCTGAAACCT 1440 TCCTTCTCCG ACGGCCTCAA GATGGACGCG GGCATCATCT GTGATGTGTG CACCTGCGAG 1500
CTGCAAAAAG AGGTGCGGTC AGCTCGCTGC AGCTTCAACG GAGACTTCGT GTGCGGACAG 1560
TGTGTGTGCA GCGAGGGCTG GAGTGGCCAG ACCTGCAACT GCTCCACCGG CTCTCTGAGT 1620
GACATTCAGC CCTGCCTGCG GGAGGGCGAG GACAAGCCGT GCTCCGGCCG TGGGGAGTGC 1680
CAGTGCGGGC ACTGTGTGTG CTACGGCGAA GGCCGCTACG AGGGTCAGTT CTGCGAGTAT 1740
GACAACTTCC AGTGTCCCCG CACTTCCGGG TTCCTCTGCA ATGACCGAGG ACGCTGCTCC 1800
ATGGGCCAGT GTGTGTGTGA GCCTGGTTGG ACAGGCCCAA GCTGTGACTG TCCCCTCAGC 1860
AATGCCACCT GCATCGACAG CAATGGGGGC ATCTGTAATG GACGTGGCCA CTGTGAGTGT 1920
GGCCGCTGCC ACTGCCACCA GCAGTCGCTC TACACGGACA CCATCTGCGA GATCAACTAC 1980
TCGGCGATCC ACCCGGGCCT CTGCGAGGAC CTACGCTCCT GCGTGCAGTG CCAGGCGTGG 2040
GGCACCGGCG AGAAGAAGGG GCGCACGTGT GAGGAATGCA ACTTCAAGGT CAAGATGGTG 2100
GACGAGCTTA AGAGAGCCGA GGAGGTGGTG GTGCGCTGCT CCTTCCGGGA CGAGGATGAC 2160
GACTGCACCT ACAGCTACAC CATGGAAGGT GACGGCGCCC CTGGGCCCAA CAGCACTGTC 2220
CTGGTGCACA AGAAGAAGGA CTGCCCTCCG GGCTCCTTCT GGTGGCTCAT CCCCCTGCTC 2280
CTCCTCCTCC TGCCGCTCCT GGCCCTGCTA CTGCTGCTAT GCTGGAAGTA CTGTGCCTGC 2340
TGCAAGGCCT GCCTGGCACT TCTCCCGTGC TGCAACCGAG GTCACATGGT GGGCTTTAAG 2400
GAAGACCACT ACATGCTGCG GGAGAACCTG ATGGCCTCTG ACCACTTGGA CACGCCCATG 2460
CTGCGCAGCG GGAACCTCAA GGGCCGTGAC GTGGTCCGCT GGAAGGTCAC CAACAACATG 2520
CAGCGGCCTG GCTTTGCCAC TCATGCCGCC AGCATCAACC CCACAGAGCT GGTGCCCTAC 2580
GGGCTGTCCT TGCGCCTGGC CCGCCTTTGC ACCGAGAACC TGCTGAAGCC TGACACTCGG 2640
GAGTGCGCCC AGCTGCGCCA GGAGGTGGAG GAGAACCTGA ACGAGGTCTA CAGGCAGATC 2700
TCCGGTGTAC ACAAGCTCCA GCAGACCAAG TTCCGGCAGC AGCCCAATGC CGGGAAAAAG 2760
CAAGACCACA CCATTGTGGA CACAGTGCTG ATGGCGCCCC GCTCGGCCAA GCCGGCCCTG 2820
CTGAAGCTTA CAGAGAAGCA GGTGGAACAG AGGGCCTTCC ACGACCTCAA GGTGGCCCCC 2880
GGCTACTACA CCCTCACTGC AGACCAGGAC GCCCGGGGCA TGGTGGAGTT CCAGGAGGGC 2940
GTGGAGCTGG TGGACGTACG GGTGCCCCTC TTTATCCGGC CTGAGGATGA CGACGAGAAG 3000
CAGCTGCTGG TGGAGGCCAT CGACGTGCCC GCAGGCACTG CCACCCTCGG CCGCCGCCTG 3060
GTAAACATCA CCATCATCAA GGAGCAAGCC AGAGACGTGG TGTCCTTTGA GCAGCCTGAβ 3120
TTCTCGGTCA GCCGCGGGGA CCAGGTGGCC CGCATCCCTG TCATCCGGCG TGTCCTGGAC 3180
GGCGGGAAGT CCCAGGTCTC CTACCGCACA CAGGATGGCA CCGCGCAGGG CAACCGGGAC 3240
TACATCCCCβ TGGAGGGTGA GCTGCTGTTC CAGCCTGGGG AGGCCTGGAA AGAGCTGCAG 3300
GTGAAGCTCC TGGAGCTGCA AGAAGTTGAC TCCCTCCTGC GGGGCCGCCA GGTCCGCCGT 3360
TTCCACGTCC AGCTCAGCAA CCCTAAGTTT GGGGCCCACC TGGGCCAGCC CCACTCCACC 3420
ACCATCATCA TCAGGGACCC AGATGAACTG GACCGGAGCT TCACGAGTCA GATGTTGTCA 3480
TCACAGCCAC CCCCTCACGG CGACCTGGGC GCCCCGCAGA ACCCCAATGC TAAGGCCGCT 3540
GGGTCCAGGA AGATCCATTT CAACTGGCTG CCCCCTTCTG GCAAGCCAAT GGGGTACAGG 3600
GTAAAGTACT GGATTCAGGG TGACTCCGAA TCCGAAGCCC ACCTGCTCGA CAGCAAGGTG 3660
CCCTCAGTGG AGCTCAGCAA CCTGTACCCG TATTGCGACT ATGAGATGAA GGTGTGCGCC 3720
TACGGGGCTC AGGGCGAGGG ACCCTACAGC TCCCTGGTGT CCTGCCGCAC CCACCAGGAA 3780
GTGCCCAGCG AGCCAGGGCG TCTGGCCTTC AATGTCGTCT CCTCCACGGT GACCCAGCTG 3840
AGCTGGGCTG AGCCGGCTGA GACCAACGGT GAGATCACAG CCTACGAGGT CTGCTATGGC 3900
CTGGTCAACG ATGACAACCG ACCTATTGGG CCCATGAAGA AAGTGCTGGT TGACAACCCT 3960
AAGAACCGGA TGCTGCTTAT TGAGAACCTT CGGGAGTCCC AGCCCTACCG CTACACGGTG 4020
AAGGCGCGCA ACGGGGCCGG CTGGGGGCCT GAGCGGGAGG CCATCATCAA CCTGGCCACC 4080
CAGCCCAAGA GGCCCATGTC CATCCCCATC ATCCCTGACA TCCCTATCGT GGACβCCCAG 4140
AGCGGGGAGG ACTACGACAG CTTCCTTATG TACAGCGATG ACGTTCTACG CTCTCCATCG 4200
GGCAGCCAGA GGCCCAGCGT CTCCGATGAC ACTGAGCACC TGGTGAATGG CCGGATGGAC 4260
TTTGCCTTCC CGGGCAGCAC CAACTCCCTG CACAGGATGA CCACGACCAG TGCTGCTGCC 4320
TATGGCACCC ACCTGAGCCC ACACGTGCCC CACCGCGTGC TAAGCACATC CTCCACCCTC 4380
ACACGGGACT ACAACTCACT GACCCGCTCA GAACACTCAC ACTCGACCAC ACTGCCGAGG 4440
GACTACTCCA CCCTCACCTC CGTCTCCTCC CACGACTCTC GCCTGACTGC TGGTGTGCCC 4500
GACACGCCCA CCCGCCTGGT GTTCTCTGCC CTGGGGCCCA CATCTCTCAG AGTGAGCTGG 4560
CAGGAGCCGC GGTGCGAGCG GCCGCTGCAG GGCTACAGTG TGGAGTACCA GCTGCTGAAC 4620
GGCGGTGAGC TGCATCGGCT CAACATCCCC AACCCTGCCC AGACCTCGGT GGTGGTGGAA 4680
GACCTCCTGC CCAACCACTC CTACGTGTTC CGCGTGCGGG CCCAGAGCCA GGAAGGCTGG 4740
GGCCGAGAGC GTGAGGGTGT CATCACCATT GAATCCCAGG TGCACCCGCA GAGCCCACTG 4800
TGTCCCCTGC CAGGCTCCGC CTTCACTTTG AGCACTCCCA GTGCCCCAGG CCCGCTGGTG 4860
TTCACTGCCC TGAGCCCAGA CTCGCTGCAG CTGAGCTGGG AGCGGCCACG GAGGCCCAAT 4920
GGGGATATCG TCGGCTACCT GGTGACCTGT GAGATGGCCC AAGGAGGAGG GCCAGCCACC 4980 GCATTCCGGG TGGATGGAGA CAGCCCCGAG AGCCGGCTGA CCGTGCCGGG CCTCAGCGAG 5040 AACGTGCCCT ACAAGTTCAA GGTGCAGGCC AGGACCACTG AGGGCTTCGG GCCAGAGCGC 5100 GAGGGCATCA TCACCATAGA GTCCCAGGAT GGAGGACCCT TCCCGCAGCT GGGCAGCCGT 5160 GCCGGGCTCT TCCAGCACCC GCTGCAAAGC GAGTACAGCA GCATCACCAC CACCCACACC 5220 AGCGCCACCG AGCCCTTCCT AGTGGATGGG CCGACCCTGG GGGCCCAGCA CCTGGAGGCA 5280 GGCGGCTCCC TCACCCGGCA TGTGACCCAG GAGTTTGTGA GCCGGACACT GACCACCAGC 5340 GGAACCCTTA GCACCCACAT GGACCAACAG TTCTTCCAAA CTTGACCGCA CCCTGCCCCA 5400 CCCCCGCCAT GTCCCACTAG GCGTCCTCCC GACTCCTCTC CCGGAGCCTC CTCAGCTACT 5460 CCATCCTTGC ACCCCTGGGG GCCCAGCCCA CCCGCATGCA CAGAGCAGGG GCTAGGTGTC 5520 TCCTGGGAGG CATGAAGGGG GCAAGGTCCG TCCTCTGTGG GCCCAAACCT ATTTGTAACC 5580 AAAGAGCTGG GAGCAGCACA AGGACCCAGC CTTTGTTCTG CACTTAATAA ATGGTTTTGC 5640 TACTG
Seq ID NO: 360 Protein sequence Protein Accession ft: NP 000204.1
11 21 31 41 51
I I I I
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR 60 CNTQAELLAA GCQRESIWM ESSFQITEET QIDTTLRRSQ MSPQGLRVRL RPGEERHFEL 120 EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIG FGKFVDKVSV 180 PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL 240 QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADGANVLAGI MSRNDERCHL DTTGTYTQYR 300 TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE 360 EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG 420 THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCGQCV 480 CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN 540 FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR 600 CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE 660 LKRAEEVWR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPGS FWWLIPLLLL 720 LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR 780 SGNLKGRDW RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC 840 AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK 900 LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL 960 LVEAIDVPAG TATLGRRLVN ITIIKEQARD WSFEQPEFS VSRGDQVARI PVIRRVLDGG 1020 KSQVSYRTQD GTAQGHRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH 1080 VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS 1140 RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG 1200 AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV 1260 NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP 1320 KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTE HLVNGRMDFA 1380 FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH SHSTTLPRDY 1440 STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY SVEYQLLNGG 1500 ELHRLNIPNP AQTSVWEDL LPNHSYVFRV RAQSQEGWGR EREGVITIES QVHPQSPLCP 1560 LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVGYLVTCEM AQGGGPATAF 1620 RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG PFPQLGSRAG 1680 LFQHPLQSEY SSITTTHTSA TEPFLVDGPT LGAQHLEAGG SLTRHVTQEF VSRTLTTSGT 1740 LSTHMDQQFF QT
Seq ID NO: 361 DNA sequence
Nucleic Acid Accession #: NM_013332.1
Coding sequence : 1..63
11 21 31 41 51
I I I I I
GCACGAGGGC GCTTTTGTCT CCGGTGAGTT TTGTGGCGGG AAGCTTCTGC GCTGGTGCTT 60 AGTAACCGAC TTTCCTCCGG ACTGCTGCAC GACCTGCTCC TACAGCCGGC GATCCACTCC 120 CGGCTGTTCC CCCGGAGGGT CCAGAGGCCT TTCAGAAGGA GAAGGCAGCT CTGTTTCTCT 180 GCAGAGGAGT AGGGTCCTTT CAGCCATGAA GCATGTGTTG AACCTCTACC TGTTAGGTGT 240 GGTACTGACC CTACTCTCCA TCTTCGTTAG AGTGATGGAG TCCCTAGAAG GCTTACTAGA 300 GAGCCCATCG CCTGGGACCT CCTGGACCAC CAGAAGCCAA CTAGCCAACA CAGAGCCCAC 360 CAAGGGCCTT CCAGACCATC CATCCAGAAG CATGTGATAA GACCTCCTTC CATACTGGCC 420 ATATTTTGGA ACACTGACCT AGACATGTCC AGATGGGAGT CCCATTCCTA GCAGACAAGC 480 TGAGCACCGT TGTAACCAGA GAACTATTAC TAGGCCTTGA AGAACCTGTC TAACTGGATG 540 CTCATTGCCT GGGCAAGGCC TGTTTAGGCC GGTTGCGGTG GCTCATGCCT GTAATCCTAG 600
CACTTTGGGA GGCTGAGGTG GGTGGATCAC CTGAGGTCAG GAGTTCGAGA CCAGCCTCGC 660 CAACATGGCG AAACCCCATC TCTACTAAAA ATACAAAAGT TAGCTGGGTG TGGTGGCAGA 720 GGCCTGTAAT CCCAGTTCCT TGGGAGGCTG AGGCGGGAGA ATTGCTTGAA CCCGGGGACG 780 GAGGTTGCAG TGAACCGAGA TCGCACTGCT GTACCCAGCC TGGGCCACAG TGCAAGACTC 840 CATCTCAAAA AAAAAAAGAA AAGAAAAAGC CTGTTTAATG CACAGGTGTG AGTGGATTGC 900 TTATGGCTAT GAGATAGGTT GATCTCGCCC TTACCCCGGG GTCTGGTGTA TGCTGTGCTT 960 TCCTCAGCAG TATGGCTCTG ACATCTCTTA GATGTCCCAA CTTCAGCTGT TGGGAGATGG 1020 TGATATTTTC AACCCTACTT CCTAAACATC TGTCTGGGGT TCCTTTAGTC TTGAATGTCT 1080 TATGCTCAAT TATTTGGTGT TGAGCCTCTC TTCCACAAGA GCTCCTCCAT GTTTGGATAG 1140 CAGTTGAAGA GGTTGTGTGG GTGGGCTGTT GGGAGTGAGG ATGGAGTGTT CAGTGCCCAT 1200 TTCTCATTTT ACATTTTAAA GTCGTTCCTC CAACATAGTG TGTATTGGTC TGAAGGGGGT 1260 GGTGGGATGC CAAAGCCTGC TCAAGTTATG GACATTGTGG CCACCATGTG GCTTAAATGA 1320 TTTTTTCTAA CTAATAAAGT GGAATATATA TTTCAAAAAA AAAAAAAAAA AA
Seq ID NO: 362 Protein sequence Protein Accesεion ft: NP 037464.1
1 11 21 31 41 51
I I I I I I
MKHVLNLYLL GWLTLLSIF VRVMESLEGL LESPSPGTSW TTRSQLANTE PTKGLPDHPS 60 RSM
Seq ID NO: 363 DNA sequence Nucleic Acid Accession ft: NM_023915.1 Coding sequence : 250 . .1326
11 21 31 41 51
GGCACGAGGG TTTCGTTTTC ATGCTTTACC AGAAAATCCA CTTCCCTGCC GACCTTAGTT 60 TCAAAGCTTA TTCTTAATTA GAGACAAGAA ACCTGTTTCA ACTTGAAGAC ACCGTATGAG 120 GTGAATGGAC AGCCAGCCAC CACAATGAAA GAAATCAAAC CAGGAATAAC CTATGCTGAA 180 CCCACGCCTC AATCGTCCCC AAGTGTTTCC TGACACGCAT CTTTGCTTAC AGTGCATCAC 240 AACTGAAGAA TGGGGTTCAA CTTGACGCTT GCAAAATTAC CAAATAACGA GCTGCACGGC 300 CAAGAGAGTC ACAATTCAGG CAACAGGAGC GACGGGCCAG GAAAGAACAC CACCCTTCAC 360 AATGAATTTG ACACAATTGT CTTGCCGGTG CTTTATCTCA TTATATTTGT GGCAAGCATC 420 TTGCTGAATG GTTTAGCAGT GTGGATCTTC TTCCACATTA GGAATAAAAC CAGCTTCATA 480 TTCTATCTCA AAAACATAGT GGTTGCAGAC CTCATAATGA CGCTGACATT TCCATTTCGA 540 ATAGTCCATG ATGCAGGATT TGGACCTTGG TACTTCAAGT TTATTCTCTG CAGATACACT 600 TCAGTTTTGT TTTATGCAAA CATGTATACT TCCATCGTGT TCCTTGGGCT GATAAGCATT 660 GATCGCTATC TGAAGGTGGT CAAGCCATTT GGGGACTCTC GGATGTACAG CATAACCTTC 720 ACGAAGGTTT TATCTGTTTG TGTTTGGGTG ATCATGGCTG TTTTGTCTTT GCCAAACATC 780 ATCCTGACAA ATGGTCAGCC AACAGAGGAC AATATCCATG ACTGCTCAAA ACTTAAAAGT 840 CCTTTGGGGG TCAAATGGCA TACGGCAGTC ACCTATGTGA ACAGCTGCTT GTTTGTGGCC 900 GTGCTGGTGA TTCTGATCGG ATGTTACATA GCCATATCCA GGTACATCCA CAAATCCAGC 960 AGGCAATTCA TAAGTCAGTC AAGCCGAAAG CGAAAACATA ACCAGAGCAT CAGGGTTGTT 1020
GTGGCTGTGT TTTTTACCTG CTTTCTACCA TATCACTTGT GCAGAATTCC TTTTACTTTT 1080
AGTCACTTAG ACAGGCTTTT AGATGAATCT GCACAAAAAA TCCTATATTA CTGCAAAGAA 1140
ATTACACTTT TCTTGTCTGC GTGTAATGTT TGCCTGGATC CAATAATTTA CTTTTTCATG 1200
TGTAGGTCAT TTTCAAGAAG GCTGTTCAAA AAATCAAATA TCAGAACCAG GAGTGAAAGC 1260
ATCAGATCAC TGCAAAGTGT GAGAAGATCG GAAGTTCGCA TATATTATGA TTACACTGAT 1320
GTGTAGGCCT TTTATTGTTT GTTGGAATCG ATATGTACAA AGTGTAAATA AATGTTTCTT 1380 TTCATTATCC TTAAAAAAAA AA
Seq ID NO : 364 Protein sequence Protein Accesεion it : NP_076404
1 11 21 31 41 51
I I I I I I
MGFNLTLAKL PNNELHGQES HNSGNRSDGP GKNTTLHNEF DTIVLPVLYL I IFVASILLN 60
GLAVWIFFHI RNKTSFIFYL KNIWADL1M TLTFPFRIVH DAGFGPWYFK FILCRYTSVL 120
FYANMYTSIV FLGLISIDRY LKWKPFGDS RMYSITFTKV LSVCVWVIMA VLSLPNIILT 180
NGQPTEDNIH DCSKLKSPLG VKWHTAVTYV NSCLFVAVLV ILIGCYIAIS RYIHKSSRQF 240
ISQSSRKRKH NQSIRVWAV FFTCFLPYHL CRIPFTFSHL DRLLDESAQK ILYYCKEITL 300 FLSACNVCLD PIIYFFMCRS FSRRLFKKSN IRTRSESIRS LQSVRRSEVR IYYDYTDV
Seq ID NO : 365 DNA sequence
Nucleic Acid Accession ft : NM_005365 . 1
Coding sequence : 1. . 948
1 11 21 31 41 51
I I I I I I
ATGTCTCTCG AGCAGAGGAG TCCGCACTGC AAGCCTGATG AAGACCTTGA AGCCCAAGGA 60
GAGGACTTGG GCCTGATGGG TGCACAGGAA CCCACAGGCG AGGAGGAGGA GACTACCTCC 120
TCCTCTGACA GCAAGGAGGA GGAGGTGTCT GCTGGTGGGT CATCAAGTCC TCCCCAGAGT 180
CCTCAGGGAG GCGCTTCCTC CTCCATTTCC GTCTACTACA CTTTATGGAG CCAATTCGAT 240
GAGGGCTCCA GCAGTCAAGA AGAGGAAGAG CCAAGCTCCT CGGTCGACCC AGCTCAGCTG 300
GAGTTCATGT TCCAAGAAGC ACTGAAATTG AAGGTGGCTG AGTTGGTTCA TTTCCTGCTC 360
CACAAATATC GAGTCAAGGA GCCGGTCACA AAGGCAGAAA TGCTGGAGAG CGTCATCAAA 420
AATTACAAGC GCTACTTTCC TGTGATCTTC GGCAAAGCCT CCGAGTTCAT GCAGGTGATC 480
TTTGGCACTG ATGTGAAGGA GGTGGACCCC GCCGGCCACT CCTACATCCT TCTCACTGCT 540
CTTGβCCTCT CGTGCGATAG CATGCTGGGT GATGGTCATA GCATGCCCAA GGCCGCCCTC 600
CTGATCATTG TCCTGGGTGT GATCCTAACC AAAGACAACT GCGCCCCTGA AGAGGTTATC 660
TGGGAAGCGT TGAGTGTGAT GGGGGTGTAT GTTGGGAAGG AGCACATGTT CTACGGGGAG 720
CCCAGGAAGC TGCTCACCCA AGATTGGGTG CAGGAAAACT ACCTGGAGTA CCGGCAGGTG 780
CCCGGCAGTG ATCCTGCGCA CTACGAGTTC CTGTGGGGTT CCAAGGCCCA CGCTGAAACC 840
AGCTATGAGA AGGTCATAAA TTATTTGGTC ATGCTCAATG CAAGAGAGCC CATCTGCTAC 900 CCATCCCTTT ATGAAGAGGT TTTGGGAGAG GAGCAAGAGG GAGTCTGA
Seq ID NO : 366 Protein sequence Protein Accession ft : NP_005356 .1
1 11 21 31 41 51
I I I I I I
MSLEQRSPHC KPDEDLEAQG EDLGLMGAQE PTGEEEETTS SSDSKEEEVS AAGSSSPPQS 60
PQGGASSSIS VYYTLWSQFD EGSSSQEEEE PSSSVDPAQL EFMFQEALKL KVAELVHFLL 120
HKYRVKEPVT KAEMLESVIK NYKRYFPVIF GKASEFMQVI FGTDVKEVDP AGHSYILVTA 180
LGLSCDSMLG DGHSMPKAAL LIIVLGVILT KDNCAPEEVI WEALSVMGVY VGKEHMFYGE 240
PRKLLTQDWV QENYLEYRQV PGSDPAHYEF LWGSKAHAET SYEKVINYLV MLNAREPICY 300 PSLYEEVLGE EQEGV
Seq ID NO : 367 DNA sequence Nucleic Acid Accession ft : NM_014400 Coding sequence : 86 . . 1126
1 11 21 31 41 51
I I I I I I
GGTTACTCAT CCTGGGCTCA GGTAAGAGGG CCCGAGCTCG GAGGCGGCAC ACCCAGGGGG 60
GACGCCAAGG GAGCAGGACG GAGCCATGGA CCCCGCCAGG AAAGCAGGTG CCCAGGCCAT 120
GATCTGGACT GCAGGCTGGC TGCTGCTGCT GCTGCTTCGC GGAGGAGCGC AGGCCCTGGA 180
GTGCTACAGC TGCGTGCAGA AAGCAGATGA CGGATGCTCC CCGAACAAGA TGAAGACAGT 240
GAAGTGCGCG CCGGGCGTGG ACGTCTGCAC CGAGGCCGTG GGGGCGGTGG AGACCATCCA 300
CGGACAATTC TCGCTGGCAG TGCSGGGTTG CGGTTCGGGA CTCCCCGGCA AGAATGACCG 360
CGGCCTGGAT CTTCACGGGC TTCTGGCGTT CATCCAGCTG CAGCAATGCG CTCAGGATCG 420
CTGCAACGCC AAGCTCAACC TCACCTCGCG GGCGCTCGAC CCGGCAGGTA ATGAGAGTGC 480
ATACCCGCCC AACGGCGTGG AGTGCTACAG CTGTGTGGGC CTGAGCCGGG AGGCGTGCCA 540
GGGTACATCG CCGCCGGTCG TGAGCTGCTA CAACGCCAGC GATCATGTCT ACAAGGGCTG 600
CTTCGACGGC AACGTCACCT TGACGGCAGC TAATGTGACT GTGTCCTTGC CTGTCCGGGG 660
CTGTGTCCAG GATGAATTCT GCACTCGGGA TGGAGTAACA GGCCCAGGGT TCACGCTCAG 720
TGGCTCCTGT TGCCAGGGGT CCCGCTGTAA CTCTGACCTC CGCAACAAGA CCTACTTCTC 780
CCCTCGAATC CCACCCCTTG TCCGGCTGCC CCCTCCAGAG CCCACGACTG TGGCCTCAAC 840
CACATCTGTC ACCACTTCTA CCTCGGCCCC AGTGAGACCC ACATCCACCA CCAAACCCAT 900
GCCAGCGCCA ACCAGTCAGA CTCCGAGACA GGGAGTAGAA CACGAGGCCT CCCGGGATGA 960
GGAGCCCAGG TTGACTGGAG GCGCCGCTGG CCACCAGGAC CGCAGCAATT CAGGGCAGTA 1020
TCCTGCAAAA GGGGGGCCCC AGCAGCCCCA TAATAAAGGC TGTGTGGCTC CCACAGCTGG 1080
ATTGGCAGCC CTTCTGTTGG CCGTGGCTGC TGGTGTCCTA CTGTGAGCTT CTCCACCTGG 1140
AAATTTCCCT CTCACCTACT TCTCTGGCCC TGGGTACCCC TCTTCTCATC ACTTCCTGTT 1200
CCCACCACTG GACTGGGCTG GCCCAGCCCC TGTTTTTCCA ACATTCCCCA GTATCCCCAG 1260
CTTCTGCTGC GCTGGTTTGC GGCTTTGGGA AATAAAATAC CGTTGTATAT ATTCTGGCAG 1320 GGGTGTTCTA GCTTTTTGAG GACAGCTCCT GTATCCTTCT CATCCTTGTC TCTCCGCTTG 1380 TCCTCTTGTG ATGTTAGGAC AGAGTGAGAG AAGTCAGCTG TCACGGGGAA GGTGAGAGAG 1440 AGGATGCTAA GCTTCCTACT CACTTTCTCC TAGCCAGCCT GGACTTTGGA GCGTGGGGTG 1500 GGTGGGACAA TGGCTCCCCA CTCTAAGCAC TGCCTCCCCT ACTCCCCGCA TCTTTGGGGA 1560 ATCGGTTCCC CATATGTCTT CCTTACTAGA CTGTGAGCTC CTCGAGGGCA GGGACCGTGC 1620 CTTATGTCTG TGTGTGATCA GTTTCTGGCA CATAAATGCC TCAATAAAGA TTTAATTACT 1680 TTGTATAGTG AAAAAAAA
Seq ID NO: 368 Protein sequence Protein Accession #: NP 055215
1 11 21 31 41 51 1 1 1 1 11 11 11 1 1
MDPARKAGAQ AMIWTAGWLL LLLLRGGAQA LECYSCVQKA DDGCSPNKMK TVKCAPGVDV 60
CTEAVGAVET IHGQFSLAVX GCGSGLPGKN DRGLDLHGLL AFIQLQQCAQ DRCNAKLNLT 120
SRALDPAGNE SAYPPNGVEC YSCVGLSREA CQGTSPPWS CYNASDHVYK GCFDGNVTLT 180
AANVTVSLPV RGCVQDEFCT RDGVTGPGFT LSGSCCQGSR CNSDLRNKTY FSPRIPPLVR 240
LPPPEPTTVA STTSVTTSTS APVRPTSTTK PMPAPTSQTP RQGVEHEASR DEEPRLTGGA 300
AGHQDRSNSG QYPAKGGPQQ PHNKGCVAPT AGLAALLLAV AAGVLL
Seq ID NO: 369 DNA sequence
Nucleic Acid Accession #: NM_005329.1 Coding sequence: 1..1662
60
120
Figure imgf001095_0001
180
CTTTTTGCCT TCCTGGAGCA CCGGCGCATG CGACGTGCCG GCCAGGCCCT GAAGCTGCCC 240
TCCCCGCGGC GGGGCTCGGT GGCACTGTGC ATTGCCGCAT ACCAGGAGGA CCCTGACTAC 300
TTGCGCAAGT GCCTGCGCTC GGCCCAGCGC ATCTCCTTCC CTGACCTCAA GGTGGTCATG 360
GTGGTGGATG GCAACCGCCA GGAGGACGCC TACATGCTGG ACATCTTCCA CGAGGTGCTG 420.
GGCGGCACCG AGCAGGCCGG CTTCTTTGTG TGGCGCAGCA ACTTCCATGA GGCAGGCGAG 480
GGTGAGACGG AGGCCAGCCT GCAGGAGGGC ATGGACCGTG TGCGGGATGT GGTGCGGGCC 540
AGCACCTTCT CGTGCATCAT GCAGAAGTGG GGAGGCAAGC GCGAGGTCAT GTACACGGCC 600
TTCAAGGCCC TCGGCGATTC GGTGGACTAC ATCCAGGTGT GCGACTCTGA CACTGTGCTG 660
GATCCAGCCT GCACCATCGA GATGCTTCGA GTCCTGGAGG AGGATCCCCA AGTAGGGGGA 720
GTCGGGGGAG ATGTCCAGAT CCTCAACAAG TACGACTCAT GGATTTCCTT CCTGAGCAGC 780
GTGCGGTACT GGATGGCCTT CAACGTGGAG CGGGCCTGCC AGTCCTACTT TGGCTGTGTG 840
CAGTGTATTA GTGGGCCCTT GGGCATGTAC CGCAACAGCC TCCTCCAGCA GTTCCTGGAG 900
GACTGGTACC ATCAGAAGTT CCTAGGCAGC AAGTGCAGCT TCGGGGATGA CCGGCACCTC 960
ACCAACCGAG TCCTGAGCCT TGGCTACCGA ACTAAGTATA CCGCGCGCTC CAAGTGCCTC 1020
ACAGAGACCC CCACTAAGTA CCTCCGGTGG CTCAACCAGC AAACCCGCTG GAGCAAGTCT 1080
TACTTCCGGG AGTGGCTCTA CAACTCTCTG TGGTTCCATA AGCACCACCT CTGGATGACC 1140
TACGAGTCAG TGGTCACGGG TTTCTTCCCC TTCTTCCTCA TTGCCACGGT TATACAGCTT 1200
TTCTACCGGG GCCGCATCTG GAACATTCTC CTCTTCCTGC TGACGGTGCA GCTGGTGGGC 1260
ATTATCAAGG CCACCTACGC CTGCTTCCTT CGGGGCAATG CAGAGATGAT CTTCATGTCC 1320
CTCTACTCCC TCCTCTATAT GTCCAGCCTT CTGCCGGCCA AGATCTTTGC CATTGCTACC 1380
ATCAACAAAT CTGGCTGGGG CACCTCTGGC CGAAAAACCA TTGTGGTGAA CTTCATTGGC 1440
CTCATTCCTG TGTCCATCTG GGTGGCAGTT CTCCTGGAGG GGCTGGCCTA CACAGCTTAT 1500
TGCCAGGACC TGTTCAGTGA GACAGAGCTA GCCTTCCTTG TCTCTGGGGC TATACTGTAT 1560
GGCTGCTACT GGGTGGCCCT CCTCATGCTA TATCTGGCCA TCATCGCCCG GCGATGTGGG 1620
AAGAAGCCGG AGCAGTACAG CTTGGCTTTT GCTGAGGTGT GA
Seq ID NO: 370 Protein sequence
Protein Accession it: NP 005320.1
11 21 31 41 51
I I I I I
MPVQLTTALR WGTSLFALA VLGGILAAYV TGYQFIHTEK HYLSFGLYGA ILGLHLLIQS 60 LFAFLEHRRM RRAGQALKLP SPRRGSVALC IAAYQEDPDY LRKCLRSAQR ISFPDLKWM 120 WDGNRQEDA YMLDIFHEVL GGTEQAGFFV WRSNFHEAGE GETEASLQEG MDRVRDWRA 180 STFSCIMQKW GGKREVMYTA FKALGDSVDY IQVCDSDTVL DPACTIEMLR VLEEDPQVGG 240 VGGDVQILNK YDSWISFLSS VRYWMAFNVE RACQSYFGCV QCISGPLGMY RNSLLQQFLE 300 DWYHQKFLGS KCSFGDDRHL TNRVLSLGYR TKYTARSKCL TETPTKYLRW LNQQTRWSKS 360 YFREWLYNSL WFHKHHLWMT YESWTGFFP FFLIATVIQL FYRGRIWNIL LFLLTVQLVG 420 IIKATYACFL RGNAEMIFMS LYSLLYMSSL LPAKIFAIAT INKSGWGTSG RKTIWNFIG 480 LIPVSIWVAV LLEGLAYTAY CQDLFSETEL AFLVSGAILY GCYWVALLML YLAIIARRCG 540 KKPEQYSLAF AEV
Seq ID NO: 371 DNA sequence
Nucleic Acid Accesεion ft: Eoε sequence
Coding sequence: 148-7095
1 11 21 31 41 51 1 1 | 1 1 | 1 |1 I 1 CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60
CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120
CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180
CAGCTCCTCT GTGTTTGCCG CCTβGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG CTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300
AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360
CAAGTAAATG TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420 AACACATTCA TTCATAACAC TGGGAAAACA GTGGAAATTA ATCTCACTAA TGACTACCGT 480 GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AGATAACTTT TCACTGGGGA 540 AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600 GAGATGCAAA TCTACTGCTT TGATGCGGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660 GGAAAAGGGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720 GATTTCAAAG CβATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780 TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840 AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900 ACAGTTAGCA TCTCTGAAAG CCAGTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960 TCTGGTTATG TCATGCTGAT GGACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020 TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGGAAG AGATTCATGA AGCAGTTTGT 1080 AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140 TGGGAAAGAC CTCGAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAG 1200 CAGTTGGATG GAGAGGACCA AACCAAGCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260 GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAGAT AGTAGCCATA 1320 TGCACTAATG GCTTATATGG AAAATACAGC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380 AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440 GAAGAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTGGTAGAGA CAGTGCTACA 1500 AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAGGG 1560 ACGAAATACA ATGAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGGA 1620 AAGGGTGATG TTCCCAATAC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680 ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740 GAAGGTACTT CAGCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800 AACTTGTCGG GGACTGCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAG 1860 AGTTTATTGA CCACTTTCAA GCTTGATACT GGAGCTGAAG ATTCTTCAGG CTCCAGTCCC 1920 GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGGGTATAT ATTTTCCTCC 1980 GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG AAATGCTTCC 2040 GAAGATTCAA CTTCATCAGG TTCAGAAGAA TCACTAAAGG ATCCTTCTAT GGAGGGAAAT 2100 GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AGGCAGAGAG 2160 AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAG 2220 TCCTTTTCTG CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280 CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340 TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400 GTATACAATG GTGAGACACC TCTTCAACCT TCCTACAGTA GTGAAGTCTT TCCTCTAGTC 2460 ACCCCTTTGT TGCTTGACAA TCAGATCCTC AACACTACCC CTGCTGCTTC AAGTAGTGAT 2520 TCGGCCTTGC ATGCTACGCC TGTATTTCCC AGTGTCGATG TGTCATTTGA ATCCATCCTG 2580 TCTTCCTATG ATGGTGCACC TTTGCTTCCA TTTTCCTCTG CTTCCTTCAG TAGTGAATTG 2640 TTTCGCCATC TGCATACAGT TTCTCAAATC CTTCCACAAG TTACTTCAGC TACCGAGAGT 2700 GATAAGGTGC CCTTGCATGC TTCTCTGCCA GTGGCTGGGG GTGATTTGCT ATTAGAGCCC 2760 AGCCTTGCTC AGTATTCTGA TGTGCTGTCC ACTACTCATG CTGCTTCAGA GACGCTGGAA 2820 TTTGGTAGTG AATCTGGTGT TCTTTATAAA ACGCTTATGT TTTCTCAAGT TGAACCACCC 2880 AGCAGTGATG CCATGATGCA TGCACGTTCT TCAGGGCCTG AACCTTCTTA TGCCTTGTCT 2940 GATAATGAGG GCTCCCAACA CATCTTCACT GTTTCTTACA GTTCTGCAAT ACCTGTGCAT 3000 GATTCTGTGG GTGTAACTTA TCAGGGTTCC TTATTTAGCG GCCCTAGCCA TATACCAATA 3060 CCTAAGTCTT CGTTAATAAC CCCAACTGCA TCATTACTGC AGCCTACTCA TGCCCTCTCT 3120 GGTGATGGGG AATGGTCTGG AGCCTCTTCT GATAGTGAAT TTCTTTTACC TGACACAGAT 3180 GGGCTGACAG CCCTTAACAT TTCTTCACCT GTTTCTGTAG CTGAATTTAC ATATACAACA 3240 TCTGTGTTTG GTGATGATAA TAAGGCGCTT TCTAAAAGTG AAATAATATA TGGAAATGAG 3300 ACTGAACTGC AAATTCCTTC TTTCAATGAG ATGGTTTACC CTTCTGAAAG CACAGTCATG 3360 CCCAACATGT ATGATAATGT AAATAAGTTG AATGCGTCTT TACAAGAAAC CTCTGTTTCC 3420 ATTTCTAGCA CCAAGGGCAT GTTTCCAGGG TCCCTTGCTC ATACCACCAC TAAGGTTTTT 3480 GATCATGAGA TTAGTCAAGT TCCAGAAAAT AACTTTTCAG TTCAACCTAC ACATACTGTC 3540 TCTCAAGCAT CTGGTGACAC TTCGCTTAAA CCTGTGCTTA GTGCAAACTC AGAGCCAGCA 3600 TCCTCTGACC CTGCTTCTAG TGAAATGTTA TCTCCTTCAA CTCAGCTCTT ATTTTATGAG 3660 ACCTCAGCTT CTTTTAGTAC TGAAGTATTG CTACAACCTT CCTTTCAGGC TTCTGATGTT 3720 GACACCTTGC TTAAAACTGT TCTTCCAGCT GTGCCCAGTG ATCCAATATT GGTTGAAACC 3780 CCCAAAGTTG ATAAAATTAG TTCTACAATG TTGCATCTCA TTGTATCAAA TTCTGCTTCA 3840 AGTGAAAACA TGCTGCACTC TACATCTGTA CCAGTTTTTG ATGTGTCGCC TACTTCTCAT 3900 ATGCACTCTG CTTCACTTCA AGGTTTGACC ATTTCCTATG CAAGTGAGAA ATATGAACCA 3960 GTTTTGTTAA AAAGTGAAAG TTCCCACCAA GTGGTACCTT CTTTGTACAG TAATGATGAG 4020 TTGTTCCAAA CGGCCAATTT GGAGATTAAC CAGGCCCATC CCCCAAAAGG AAGGCATGTA 4080 TTTGCTACAC CTGTTTTATC AATTGATGAA CCATTAAATA CACTAATAAA TAAGCTTATA 4140 CATTCCGATG AAATTTTAAC CTCCACCAAA AGTTCTGTTA CTGGTAAGGT ATTTGCTGGT 4200 ATTCCAACAG TTGCTTCTGA TACATTTGTA TCTACTGATC ATTCTGTTCC TATAGGAAAT 4260 GGGCATGTTG CCATTACAGC TGTTTCTCCC CACAGAGATG GTTCTGTAAC CTCAACAAAG 4320 TTGCTGTTTC CTTCTAAGGC AACTTCTGAG CTGAGTCATA GTGCCAAATC TGATGCCGGT 4380 TTAGTGGGTG GTGGTGAAGA TGGTGACACT GATGATGATG GTGATGATGA TGATGATGAC 4440 AGAGGTAGTG ATGGCTTATC CATTCATAAG TGTATGTCAT GCTCATCCTA TAGAGAATCA 4500 CAGGAAAAGG TAATGAATGA TTCAGACACC CACGAAAACA GTCTTATGGA TCAGAATAAT 4560 CCAATCTCAT ACTCACTATC TGAGAATTCT GAAGAAGATA ATAGAGTCAC AAGTGTATCC 4620 TCAGACAGTC AAACTGGTAT GGACAGAAGT CCTGGTAAAT CACCATCAGC AAATGGGCTA 4680 TCCCAAAAGC ACAATGATGG AAAAGAGGAA AATGACATTC AGACTGGTAG TGCTCTGCTT 4740 CCTCTCAGCC CTGAATCTAA AGCATGGGCA GTTCTGACAA GTGATGAAGA AAGTGGATCA 4800 GGGCAAGGTA CCTCAGATAG CCTTAATGAG AATGAGACTT CCACAGATTT CAGTTTTGCA 4860 GACACTAATG AAAAAGATGC TGATGGGATC CTGGCAGCAG GTGACTCAGA AATAACTCCT 4920 GGATTCCCAC AGTCCCCAAC ATCATCTGTT ACTAGCGAGA ACTCAGAAGT GTTCCACGTT 4980 TCAGAGGCAG AGGCCAGTAA TAGTAGCCAT GAGTCTCGTA TTGGTCTAGC TGAGGGGTTG 5040 GAATCCGAGA AGAAGGCAGT TATACCCCTT GTGATCGTGT CAGCCCTGAC TTTTATCTGT 5100 CTAGTβGTTC TTGTGGGTAT TCTGATCTAG TGGAGGAAAT GCTTCCAGAC TGCACACTTT 5160 TACTTAGAGG ACAGTACATC CCCTAGAGTT ATATCCACAC CTCCAACACC TATCTTTCCA 5220 ATTTCAGATG ATGTCGGAGC AATTCCAATA AAGCACTTTC CAAAGCATGT TGCAGATTTA 5280 CATGCAAGTA GTGGGTTTAC TGAAGAATTT GAGACACTGA AAGAGTTTTA CCAGGAAGTG 5340 CAGAGCTGTA CTGTTGACTT AGGTATTACA GCAGACAGCT CCAACCACCC AGACAACAAG 5400 CACAAGAATC GATACATAAA TATCGTTGCC TATGATCATA GCAGGGTTAA GCTAGCACAG 5460 CTTGCTGAAA AGGATGGCAA ACTGACTGAT TATATCAATG CCAATTATGT TGATGGCTAC 5520 AACAGACCAA AAGCTTATAT TGCTGCCCAA GGCCCACTGA AATCCACAGC TGAAGATTTC 5580 TGGAGAATGA TATGGGAACA TAATGTGGAA GTTATTGTCA TGATAACAAA CCTCGTGGAG 5640 AAAGGAAGGA GAAAATGTGA TCAGTACTGG CCTGCCGATG GGAGTGAGGA GTACGGGAAC 5700 TTTCTGGTCA CTCAGAAGAG TGTGCAAGTG CTTGCCTATT ATACTGTGAG GAATTTTACT 5760 CTAAGAAACA CAAAAATAAA AAAGGGCTCC CAGAAAGGAA GACCCAGTGG ACGTGTGGTC 5820 ACACAGTATC ACTACACGCA GTGGCCTGAC ATGGGAGTAC CAGAGTACTC CCTGCCAGTG 5880 CTGACCTTTG TGAGAAAGGC AGCCTATGCC AAGCGCCATG CAGTGGGGCC TGTTGTCGTC 5940 CACTGCAGTG CTGGAGTTGG AAGAACAGGC ACATATATTG TGCTAGACAG TATGTTGCAG 6000 CAGATTCAAC ACGAAGGAAC TGTCAACATA TTTGGCTTCT TAAAACACAT CCGTTCACAA 6060 AGAAATTATT TGGTACAAAC TGAGGAGCAA TATGTCTTCA TTCATGATAC ACTGGTTGAG 6120 GCCATACTTA GTAAAGAAAC TGAGGTGCTG GACAGTCATA TTCATGCCTA TGTTAATGCA 6180 CTCCTCATTC CTGGACCAGC AGGCAAAACA AAGCTAGAGA AACAATTCCA GCTCCTGAGC 6240 CAGTCAAATA TACAGCAGAG TGACTATTCT GCAGCCCTAA AGCAATGCAA CAGGGAAAAG 6300 AATCGAACTT CTTCTATCAT CCCTGTGGAA AGATCAAGGG TTGGCATTTC ATCCCTGAGT 6360 GGAGAAGGCA CAGACTACAT CAATGCCTCC TATATCATGG GCTATTACCA GAGCAATGAA 6420 TTCATCATTA CCCAGCACCC TCTCCTTCAT ACCATCAAGG ATTTCTGGAG GATGATATGG 6480 GACCATAATG CCCAACTGGT GGTTATGATT CCTGATGGCC AAAACATGGC AGAAGATGAA 6540 TTTGTTTACT GGCCAAATAA AGATGAGCCT ATAAATTGTG AGAGCTTTAA GGTCACTCTT 6600 ATGGCTGAAG AACACAAATG TCTATCTAAT GAGGAAAAAC TTATAATTCA GGACTTTATC 6660 TTAGAAGCTA CACAGGATGA TTATGTACTT GAAGTGAGGC ACTTTCAGTG TCCTAAATGG 6720 CCAAATCCAG ATAGCCCCAT TAGTAAAACT TTTGAACTTA TAAGTGTTAT AAAAGAAGAA 6780 GCTGCCAATA GGGATGGGCC TATGATTGTT CATGATGAGC ATGGAGGAGT GACGGCAGGA 6840 ACTTTCTGTG CTCTGACAAC CCTTATGCAC CAACTAGAAA AAGAAAATTC CGTGGATGTT 6900 TACCAGGTAG CCAAGATGAT CAATCTGATG AGGCCAGGAG TCTTTGCTGA CATTGAGCAG 6960 TATCAGTTTC TCTACAAAGT GATCCTCAGC CTTGTGAGCA CAAGGCAGGA AGAGAATCCA 7020 TCCACCTCTC TGGACAGTAA TGGTGCAGCA TTGCCTGATG GAAATATAGC TGAGAGCTTA 7080 GAGTCTTTAG TTTAACACAG AAAGGGGTGG GGGGACTCAC ATCTGAGCAT TGTTTTCCTC 7140 TTCCTAAAAT TAGGCAGGAA AATCAGTCTA GTTCTGTTAT CTGTTGATTT CCCATCACCT 7200 GACAGTAACT TTCATGACAT AGGATTCTGC CGCCAAATTT ATATCATTAA CAATGTGTGC 7260 CTTTTTGCAA GACTTGTAAT TTACTTATTA TGTTTGAACT AAAATGATTG AATTTTACAG 7320 TATTTCTAAG AATGGAATTG TGGTATTTTT TTCTGTATTG ATTTTAACAG AAAATTTCAA 7380 TTTATAGAGG TTAGGAATTC CAAACTACAG AAAATGTTTG TTTTTAGTGT CAAATTTTTA 7440 GCTGTATTTG TAGCAATTAT CAGGTTTGCT AGAAATATAA CTTTTAATAC AGTAGCCTGT 7500 AAATAAAACA CTCTTCCATA TGATATTCAA CATTTTACAA CTGCAGTATT CACCTAAAGT 7560 AGAAATAATC TGTTACTTAT TGTAAATACT GCCCTAGTGT CTCCATGGAC CAAATTTATA 7620 TTTATAATTG TAGATTTTTA TATTTTACTA CTGAGTCAAG TTTTCTAGTT CTGTGTAATT 7680 GTTTAGTTTA ATGACGTAGT TCATTAGCTG GTCTTACTCT ACCAGTTTTC TGACATTGTA 7740 TTGTGTTACC TAAGTCATTA ACTTTGTTTC AGCATGTAAT TTTAACTTTT GTGGAAAATA 7800 GAAATACCTT CATTTTGAAA GAAGTTTTTA TGAGAATAAC ACCTTACCAA ACATTGTTCA 7860 AATGGTTTTT ATCCAAGGAA TTGCAAAAAT AAATATAAAT ATTGCCATTA AAAAAAAAAA 7920 AAAAAAAAAA AAAAAAAAAA AAAA
Seq ID NO: 372 Protein sequence:
Protein Accession #: built from XP 031379
11 21 31 41 51
I I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD V IPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNGETPLQ PSYSSEVFPL VTPLLLDNQI 780 LNTTPAASSS DSALHATPVF PSVDVSFESI LSSYDGAPLL PFSSASFSSE LFRHLHTVSQ 840 ILPQVTSATE SDKVPLHASL PVAGGDLLLE PSLAQYSDVL STTHAASETL EFGSESGVLY 900 KTLMFSQVEP PSSDAMMHAR SSGPEPSYAL SDNEGSQHIF TVS SSAIPV HDSVGVTYQG 960 SLFSGPSHIP IPKSSLITPT ASLLQPTHAL SGDGEWSGAS SDSEFLLPDT DGLTALNISS 1020 PVSVAEFTYT TSVFGDDNKA LSKSEIIYGN ETELQIPSFN EMVYPSESTV MPNMYDNVNK 1080 LNASLQETSV SISSTKGMFP GSLAHTTTKV FDHEISQVPE NNFSVQPTHT VSQASGDTSL 1140 KPVLSANSEP ASSDPASSEM LSPSTQLLFY ETSASFSTEV LLQPSFQASD VDTLLKTVLP 1200 AVPSDPILVE TPKVDKISST MLHLIVSNSA SSENMLHSTS VPVFDVSPTS HMHSASLQGL 1260 TISYASEKYE PVLLKSESSH QWPSLYSND ELFQTANLEI NQAHPPKGRH VFATPVLSID 1320 EPLNTLINKL IHSDEILTST KSSVTGKVFA GIPTVASDTF VSTDHSVPIG NGHVAITAVS 1380 PHRDGSVTST KLLFPSKATS ELSHSAKSDA GLVGGGEDGD TDDDGDDDDD DRGSDGLSIH 1440 KCMSCSSYRE SQEKVMNDSD THENSLMDQN NPISYSLSEN SEEDNRVTSV SΞDSQTGMDR 1500 SPGKSPSANG LSQKHNDGKE ENDIQTGSAL LPLSPESKAW AVLTSDEESG SGQCTSDSLN 1560 ENETSTDFSF ADTNEKDADG ILAAGDSEIT PGFPQSPTSS VTSENSEVFH VSEAEASNSS 1620 HESRIGLAEG LESEKKAVIP LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR 1680 VISTPPTPIF PISDDVGAIP IKHFPKHVAD LHASSGFTEE FETLKEFYQE VQSCTVDLGI 1740 TADSSNHPDN KHKNRYINIV AYDHSRVKLA QLAEKDGKLT DYINANYVDG YNRPKAYIAA 1800 QGPLKSTAED FWRMIWEHNV EVIVMITNLV EKGRRKCDQY WPADGSEEYG NFLVTQKSVQ 1860 VLAYYTVRNF TLRNTKIKKG SQKGRPSGRV VTQYHYTQWP DMGVPEYSLP VLTFVRKAAY 1920 AKRHAVGPW VHCSAGVGRT GTYIVLDSML QQIQHEGTVN IFGFLKHIRS QRNYLVQTEE 1980 QYVFIHDTLV EAILSKETEV LDSHIHAYVN ALLIPGPAGK TKLEKQFQLL SQSNIQQSDY 2040 SAALKQCNRE KNRTSSIIPV ERSRVGISSL SGEGTDYINA SYIMGYYQSN EFIITQHPLL 2100 HTIKDFWRMI WDHNAQLWM IPDGQNMAED EFVYWPNKDE PINCESFKVT LMAEEHKCLS 2160 NEEKLIIQDF ILEATQDDYV LEVRHFQCPK WPNPDSPISK TFELISVIKE EAANRDGPMI 2220 VHDEHGGVTA GTFCALTTLM HQLEKENSVD VYQVAKMINL MRPGVFADIE QYQFLYKVIL 2280 SLVSTRQEEN PSTSLDSNGA ALPDGNIAES LESLV
Seq ID NO: 373 DNA sequence
Nucleic Acid Accession ft: built from NM_002851
Coding sequence: 148-4518
1 11 21 31 41 51
I I I I I I
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60
CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120
CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180
CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300
AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360
CAAGTAAATG TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420
AACACATTCA TTCATAACAC TGGGAAAACA GTGGAAATTA ATCTCACTAA TGACTACCGT 480
GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AGATAACTTT TCACTGGGGA 540
AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600
GAGATGCAAA TCTACTGCTT TGATGCGGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660
GGAAAAGGGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720
GATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780
TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840
AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900
ACAGTTAGCA TCTCTGAAAG CCAGTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960
TCTGGTTATG TCATGCTGAT GGACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020
TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGGAAG AGATTCATGA AGCAGTTTGT 1080
AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140
TGGGAAAGAC CTCGAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAG 1200
CAGTTGGATG GAGAGGACCA AACCAAGCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260
GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAGAT AGTAGCCATA 1320
TGCACTAATG GCTTATATGG AAAATACAβC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380
AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440
GAAGAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTGGTAGAGA CAGTGCTACA 1500
AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAGGG IS60
ACGAAATACA ATGAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGGA 1620
AAGGGTGATG TTCCCAATAC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680
ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740
GAAGGTACTT CAGCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800
AACTTGTCGG GGACTGCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAG 1860
AGTTTATTGA CCAGTTTCAA GCTTGATACT GGAGCTGAAG ATTCTTCAGG CTCCAGTCCC 1920
GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGGGTATAT ATTTTCCTCC 1980
GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG AAATGCTTCC 2040
GAAGATTCAA CTTCATCAGG TTCAGAAGAA TCACTAAAGG ATCCTTCTAT GGAGGGAAAT 2100
GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AGGCAGAGAG 2160
AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAG 2220
TCCTTTTCTG CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280
CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340
TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400
GTATACAATG CAGAGGCCAG TAATAGTAGC CATGAGTCTC GTATTGGTCT AGCTGAGGGG 2460
TTGGAATCCG AGAAGAAGGC AGTTATACCC CTTGTGATCG TGTCAGCCCT GACTTTTATC 2520
TGTCTAGTGG TTCTTGTGGG TATTCTCATC TACTGGAGGA AATGCTTCCA GACTGCACAC 2580
TTTTACTTAG AGGACAGTAC ATCCCCTAGA GTTATATCCA CACCTCCAAC ACCTATCTTT 2640
CCAATTTCAG ATGATGTCGG AGCAATTCCA ATAAAGCACT TTCCAAAGCA TGTTGCAGAT 2700
TTACATGCAA GTAGTGGGTT TACTGAAGAA TTTGAGACAC TGAAAGAGTT TTACCAGGAA 2760
GTGCAGAGCT GTACTGTTGA CTTAGGTATT ACAGCAGACA GCTCCAACCA CCCAGACAAC 2820
AAGCACAAGA ATCGATACAT AAATATCGTT GCCTATGATC ATAGCAGGGT TAAGCTAGCA 2880
CAGCTTGCTG AAAAGGATGG CAAACTGACT GATTATATCA ATGCCAATTA TGTTGATGGC 2940
TACAACAGAC CAAAAGCTTA TATTGCTGCC CAAGGCCCAC TGAAATCCAC AGCTGAAGAT 3000
TTCTGGAGAA TGATATGGGA ACATAATGTG GAAGTTATTG TCATGATAAC AAACCTCGTG 3060
GAGAAAGGAA GGAGAAAATG TGATCAGTAC TGGCCTGCCG ATGGGAGTGA GGAGTACGGG 3120
AACTTTCTGG TCACTCAGAA GAGTGTGCAA GTGCTTGCCT ATTATACTGT GAGGAATTTT 3180
ACTCTAAGAA ACACAAAAAT AAAAAAGGGC TCCCAGAAAG GAAGACCCAG TGGACGTGTG 3240
GTCACACAGT ATCACTACAC GCAGTGGCCT GACATGGGAG TACCAGAGTA CTCCCTGCCA 3300
GTGCTGACCT TTGTGAGAAA GGCAGCCTAT GCCAAGCGCC ATGCAGTGGG GCCTGTTGTC 3360
GTCCACTGCA GTGCTGGAGT TGGAAGAACA GGCACATATA TTGTGCTAGA CAGTATGTTG 3420
CAGCAGATTC AACACGAAGG AACTGTCAAC ATATTTGGCT TCTTAAAACA CATCCGTTCA 3480
CAAAGAAATT ATTTGGTACA AACTGAGGAG CAATATGTCT TCATTCATGA TACACTGGTT 3540
GAGGCCATAC TTAGTAAAGA AACTGAGGTG CTGGACAGTC ATATTCATGC CTATGTTAAT 3600
GCACTCCTCA TTCCTGGACC AGCAGGCAAA ACAAAGCTAG AGAAACAATT CCAGCTCCTG 3660
AGCCAGTCAA ATATACAGCA GAGTGACTAT TCTGCAGCCC TAAAGCAATG CAACAGGGAA 3720
AAGAATCGAA CTTCTTCTAT CATCCCTGTG GAAAGATCAA GGGTTGGCAT TTCATCCCTG 3780
AGTGGAGAAG GCACAGACTA CATCAATGCC TCCTATATCA TGGGCTATTA CCAGAGCAAT 3840
GAATTCATCA TTACCCAGCA CCCTCTCCTT CATACCATCA AGGATTTCTG GAGGATGATA 3900
TGGGACCATA ATGCCCAACT GGTGGTTATG ATTCCTGATG GCCAAAACAT GGCAGAAGAT 3960
GAATTTGTTT ACTGGCCAAA TAAAGATGAG CCTATAAATT GTGAGAGCTT TAAGGTCACT 4020
CTTATGGCTG AAGAACACAA ATGTCTATCT AATGAGGAAA AACTTATAAT TCAGGACTTT 4080
ATCTTAGAAG CTACACAGGA TGATTATGTA CTTGAAGTGA GGCACTTTCA GTGTCCTAAA 4140
TGGCCAAATC CAGATAGCCC CATTAGTAAA ACTTTTGAAC TTATAAGTGT TATAAAAGAA 4200
GAAGCTGCCA ATAGGGATGG GCCTATGATT GTTCATGATG AGGATGGAGG AGTGACGGCA 4260
GGAACTTTCT GTGCTCTGAC AACCCTTATG CACCAACTAG AAAAAGAAAA TTCCGTGGAT 4320
GTTTACCAGG TAGCCAAGAT GATCAATCTG ATGAGGCCAG GAGTCTTTGC TGACATTGAG 4380
CAGTATCAGT TTCTCTACAA AGTGATCCTC AGCCTTGTGA GCACAAGGCA GGAAGAGAAT 4440 CCATCCACCT CTCTGGACAG TAATGGTGCA GCATTGCCTG ATGGAAATAT AGCTGAGAGC 4500 TTAGAGTCTT TAGTTTAACA CAGAAAGGGG TGGGGGGACT CACATCTGAG CATTGTTTTC 4560 CTCTTCCTAA AATTAGGCAG GAAAATCAGT CTAGTTCTGT TATCTGTTGA TTTCCCATCA 4620 CCTGACAGTA ACTTTCATGA CATAGGATTC TGCCGCCAAA TTTATATCAT TAACAATGTG 4680 TGCCTTTTTG CAAGACTTGT AATTTACTTA TTATGTTTGA ACTAAAATGA TTGAATTTTA 4740 CAGTATTTCT AAGAATGGAA TTGTGGTATT TTTTTCTGTA TTGATTTTAA CAGAAAATTT 4800 CAATTTATAG AGGTTAGGAA TTCCAAACTA CAGAAAATGT TTGTTTTTAG TGTCAAATTT 4860 TTAGCTGTAT TTGTAGCAAT TATCAGGTTT GCTAGAAATA TAACTTTTAA TACAGTAGCC 4920 TGTAAATAAA ACACTCTTCC ATATGATATT CAACATTTTA CAACTGCAGT ATTCACCTAA 4980 AGTAGAAATA ATCTGTTACT TATTGTAAAT ACTGCCCTAG TGTCTCCATG GACCAAATTT 5040 ATATTTATAA TTGTAGATTT TTATATTTTA CTACTGAGTC AAGTTTTCTA GTTCTGTGTA 5100 ATTGTTTAGT TTAATGACGT AGTTCATTAG CTGGTCTTAC TCTACCAGTT TTCTGACATT 5160 GTATTGTGTT ACCTAAGTCA TTAACTTTGT TTCAGCATGT AATTTTAACT TTTGTGGAAA 5220 ATAGAAATAC CTTCATTTTG AAAGAAGTTT TTATGAGAAT AACACCTTAC CAAACATTGT 5280 TCAAATGGTT TTTATCCAAG GAATTGCAAA AATAAATATA AATATTGCCA TTAAAAAAAA 5340 AAAAAAAAAA AAAAAAAAAA AAAAAAA
Seq ID NO: 374 Protein sequence:
Protein Accession ft: built from XP 031379
11 21 31 41 51
I I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNAEASNS SHESRIGLAE GLESEKKAVI 780 PLVIVSALTF ICLWLVGIL IYWRKCFQTA HFYLEDSTSP RVISTPPTPI FPISDDVGAI 840 PIKHFPKHVA DLHASSGFTE EFETLKEFYQ EVQSCTVDLG ITADSSNHPD NKHKNRYINI 900 VAYDHSRVKL AQLAEKDGKL TDYINANYVD GYNRPKAYIA AQGPLKSTAE DFWRMIWEHN 960 VEVIVMITNL VEKGRRKCDQ YWPADGSEEY GNFLVTQKSV QVLAYYTVRN FTLRNTKIKK 1020 GSQKGRPSGR WTQYHYTQW PDMGVPEYSL PVLTFVRKAA YAKRHAVGPV WHCSAGVGR 1080 TGTYIVLDSM LQQIQHEGTV NIFGFLKHIR SQRNYLVQTE EQYVFIHDTL VEAILSKETE 1140 VLDSHIHAYV NALLIPGPAG KTKLEKQFQL LSQSNIQQSD YSAALKQCNR EKNRTSSIIP 1200 VERSRVGISS LSGEGTDYIN ASYIMGYYQS NEFIITQHPL LHTIKDFWRM IWDHNAQLW 1260 MIPDGQNMAE DEFVYWPNKD EPINCESFKV TLMAEEHKCL SNEEKLIIQD FILEATQDDY 1320 VLEVRHFQCP KWPNPDSPIS KTFELISVIK EEAANRDGPM IVHDEHGGVT AGTFCALTTL 1380 MHQLEKENSV DVYQVAKMIN LMRPGVFADI EQYQFLYKVI LSLVSTRQEE NPSTSLDSNG 1440 AALPDGNIAE SLESLV
Seq ID NO: 375 DNA sequence
Nucleic Acid Accession ff: EOS sequence
Coding sequence: 148-4494
11 21 31 41 51
I I I I I
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60 CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120 CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180 CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240 CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300 AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360 CAAGTAAATG TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420 AACACATTCA TTCATAACAC TGGGAAAACA GTGGAAATTA ATCTCACTAA TGACTACCGT 480 GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AGATAACTTT TCACTGGGGA 540 AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600 GAGATGCAAA TCTACTGCTT TGATGCAGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660 GGAAAAGGGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720 GATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780 TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840 AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900 ACAGTTAGCA TCTCTGAAAG CCAGTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960 TCTGGTTATG TCATGCTGAT GGACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020 TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGGAAG AGATTCATGA AGCAGTTTGT 1080 AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140 TGGGAAAGAC CTCGAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAG 1200 CAGTTGGATG GAGAGGACCA AACCAAGCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260 GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAGAT AGTAGCCATA 1320 TGCACTAATG GCTTATATGG AAAATACAGC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380 AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440 GAAGAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTGGTAGAGA CAGTGCTACA 1500 AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAGGG 1560 ACGAAATACA ATGAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGGA 1620 AAGGGTGATG TTCCCAATAC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680 ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740 GAAGGTACTT CAGCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800
AACTTGTCGG GGACTβCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAG 1860
AGTTTATTGA CCAGTTTCAA GCTTGATACT GGAGCTGAAG ATTCTTCAGG CTCCAGTCCC 1920
GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGGGTATAT ATTTTCCTCC 1980
GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG AAATGCTTCC 2040
GAAGATTCAA CTTCATCAGG TTCAGAAGAA TCACTAAAGG ATCCTTCTAT GGAGGGAAAT 2100
GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AGGCAGAGAG 2160
AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAG 2220
TCCTTTTCTG CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280
CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340
TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400
GTATACAATG AGGCCAGTAA TAGTAGCCAT GAGTCTCGTA TTGGTCTAGC TGAGGGGTTG 2460
GAATCCGAGA AGAAGGCAGT TATACCCCTT GTGATCGTGT CAGCCCTGAC TTTTATCTGT 2520
CTAGTGGTTC TTGTGGGTAT TCTCATCTAC TGGAGGAAAT GCTTCCAGAC TGCACACTTT 2580
TACTTAGAGG ACAGTACATC CCCTAGAGTT ATATCCACAC CTCCAACACC TATCTTTCCA 2640
ATTTCAGATG ATGTCGGAGC AATTCCAATA AAGCACTTTC CAAAGCATGT TGCAGATTTA 2700
CATGCAAGTA GTGGGTTTAC TGAAGAATTT GAGGAAGTGC AGAGCTGTAC TGTTGACTTA 2760
GGTATTACAG CAGACAGCTC CAACCACCCA GACAACAAGC ACAAGAATCG ATACATAAAT 2820
ATCGTTGCCT ATGATCATAG CAGGGTTAAG CTAGCACAGC TTGCTGAAAA GGATGGCAAA 2880
CTGACTGATT ATATCAATGC CAATTATGTT GATGGCTACA ACAGACCAAA AGCTTATATT 2940
GCTGCCCAAG GCCCACTGAA ATCCACAGCT GAAGATTTCT GGAGAATGAT ATGGGAACAT 3000
AATGTGGAAG TTATTGTCAT GATAACAAAC CTCGTGGAGA AAGGAAGGAG AAAATGTGAT 3060
CAGTACTGGC CTGCCGATGG GAGTGAGGAG TACGGGAACT TTCTGGTCAC TCAGAAGAGT 3120
GTGCAAGTGC TTGCCTATTA TACTGTGAGG AATTTTACTC TAAGAAACAC AAAAATAAAA 3180
AAGGGCTCCC AGAAAGGAAG ACCCAGTGGA CGTGTGGTCA CACAGTATCA CTACACGCAG 3240
TGGCCTGACA TGGGAGTACC AGAGTACTCC CTGCCAGTGC TGACCTTTGT GAGAAAGGCA 3300
GCCTATGCCA AGCGCCATGC AGTGGGGCCT GTTGTCGTCC ACTGCAGTGC TGGAGTTGGA 3360
AGAACAGGCA CATATATTGT GCTAGACAGT ATGTTGCAGC AGATTCAACA CGAAGGAACT 3420
GTCAACATAT TTGGCTTCTT AAAACACATC CGTTCACAAA GAAATTATTT GGTACAAACT 3480
GAGGAGCAAT ATGTCTTCAT TCATGATACA CTGGTTGAGG CCATACTTAG TAAAGAAACT 3540
GAGGTGCTGG ACAGTCATAT TCATGCCTAT GTTAATGCAC TCCTCATTCC TGGACCAGCA 3600
GGCAAAACAA AGCTAGAGAA ACAATTCCAG CTCCTGAGCC AGTCAAATAT ACAGCAGAGT 3660
GACTATTCTG CAGCCCTAAA GCAATGCAAC AGGGAAAAGA ATCGAACTTC TTCTATCATC 3720
CCTGTGGAAA GATCAAGGGT TGGCATTTCA TCCCTGAGTG GAGAAGGCAC AGACTACATC 3780
AATGCCTCCT ATATCATGGG CTATTACCAG AGCAATGAAT TCATCATTAC CCAGCACCCT 3840
CTCCTTCATA CCATCAAGGA TTTCTGGAGG ATGATATGGG ACCATAATGC CCAACTGGTG 3900
GTTATGATTC CTGATGGCCA AAACATGGCA GAAGATGAAT TTGTTTACTG GCCAAATAAA 3960
GATGAGCCTA TAAATTGTGA GAGCTTTAAG GTCACTCTTA TGGCTGAAGA ACACAAATGT 4020
CTATCTAATG AGGAAAAACT TATAATTCAG GACTTTATCT TAGAAGCTAC ACAGGATGAT 4080
TATGTACTTG AAGTGAGGCA CTTTCAGTGT CCTAAATGGC CAAATCCAGA TAGCCCCATT 4140
AGTAAAACTT TTGAACTTAT AAGTGTTATA AAAGAAGAAG CTGCCAATAG GGATGGGCCT 4200
ATGATTGTTC ATGATGAGCA TGGAGGAGTG ACGGCAGGAA CTTTCTGTGC TCTGACAACC 4260
CTTATGCACC AACTAGAAAA AGAAAATTCC GTGGATGTTT ACCAGGTAGC CAAGATGATC 4320
AATCTGATGA GGCCAGGAGT CTTTGCTGAC ATTGAGCAGT ATCAGTTTCT CTACAAAGTG 4380
ATCCTCAGCC TTGTGAGCAC AAGGCAGGAA GAGAATCCAT CCACCTCTCT GGACAGTAAT 4440
GGTGCAGCAT TGCCTGATGG AAATATAGCT GAGAGCTTAG AGTCTTTAGT TTAACACAGA 4500
AAGGGGTGGG GGGACTCACA TCTGAGCATT GTTTTCCTCT TCCTAAAATT AGGCAGGAAA 4560
ATCAGTCTAG TTCTGTTATC TGTTGATTTC CCATCACCTG ACAGTAACTT TCATGACATA 4620
GGATTCTGCC GCCAAATTTA TATCATTAAC AATGTGTGCC TTTTTGCAAG ACTTGTAATT 4680
TACTTATTAT GTTTGAACTA AAATGATTGA ATTTTACAGT ATTTCTAAGA ATGGAATTGT 4740
GGTATTTTTT TCTGTATTGA TTTTAACAGA AAATTTCAAT TTATAGAGGT TAGGAATTCC 4800
AAACTACAGA AAATGTTTGT TTTTAGTGTC AAATTTTTAG CTGTATTTGT AGCAATTATC 4860
AGGTTTGCTA GAAATATAAC TTTTAATACA GTAGCCTGTA AATAAAACAC TCTTCCATAT 4920
GATATTCAAC ATTTTACAAC TGCAGTATTC ACCTAAAGTA GAAATAATCT GTTACTTATT 4980
GTAAATACTG CCCTAGTGTC TCCATGGACC AAATTTATAT TTATAATTGT AGATTTTTAT 5040
ATTTTACTAC TGAGTCAAGT TTTCTAGTTC TGTGTAATTG TTTAGTTTAA TGACGTAGTT 5100
CATTAGCTGG TCTTACTCTA CCAGTTTTCT GACATTGTAT TGTGTTACCT AAGTCATTAA 5160
CTTTGTTTCA GCATGTAATT TTAACTTTTG TGGAAAATAG AAATACCTTC ATTTTGAAAG 5220
AAGTTTTTAT GAGAATAACA CCTTACCAAA CATTGTTCAA ATGGTTTTTA TCCAAGGAAT 5280
TGCAAAAATA AATATAAATA TTGCCATTAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 5340 AAA
Seq ID NO: 376 Protein sequence: Protein Accession ft: EOS sequence
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MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNEASNSS HESRIGLAEG LESEKKAVIP 780 LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR VISTPPTPIF PISDDVGAIP 840 IKHFPKHVAD LHASSGFTEE FEEVQSCTVD LGITADSSNH PDNKHKNRYI NIVAYDHSRV 900 KLAQLAEKDG KLTDYINANY VDGYNRPKAY IAAQGPLKST AEDFWRMIWE HNVEVIVMIT 960 NLVEKGRRKC DQYWPADGSE EYGNFLVTQK SVQVLAYYTV RNFTLRNTKI KKGSQKGRPS 1020 GRWTQYHYT QWPDMGVPEY SLPVLTFVRK AAYAKRHAVG PVWHCSAGV GRTGTYIVLD 1080 SMLQQIQHEG TVNIFGFLKH IRSQRNYLVQ TEEQYVFIHD TLVEAILSKE TEVLDSHIHA 1140 YVNALLIPGP AGKTKLEKQF QLLSQSNIQQ SDYSAALKQC NREKNRTSSI IPVERSRVGI 1200 SSLSGEGTDY INASYIMGYY QSNEFIITQH PLLHTIKDFW RMIWDHNAQL WMIPDGQNM 1260 AEDEFVYWPN KDEPINCESF KVTLMAEEHK CLSNEEKLII QDFILEATQD DYVLEVRHFQ 1320 CPKWPNPDSP ISKTFELISV IKEEAANRDG PMIVHDEHGG VTAGTFCALT TLMHQLEKEN 1380 SVDVYQVAKM INLMRPGVFA DIEQYQFLYK VILSLVSTRQ EENPSTSLDS NGAALPDGNI 1440 AESLESLV
Seq ID NO: 377 DNA sequence
Nucleic Acid Accession #: EOS sequence
Coding sequence: 501-4514
1 11 21 31 41 51
1 I I I I I
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60 CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120 CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180 CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240 CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAT TGGGGAAAGA 300 AATATCCAAC ATGTAATAGC CCAAAACAAT CTCCTATCAA TATTGATGAA GATCTTACAC 360 AAGTAAATGT GAATCTTAAG AAACTTAAAT TTCAGGGTTG GGATAAAACA TCATTGGAAA 420 AGACATTCAT TCATAACACT GGGAAAACAG TGGAAATTAA TCTCACTAAT GACTACCGTG 480 TCAGCGGAGG AGTTTCAGAA ATGGTGTTTA AAGCAAGCAA GATAACTTTT CACTGGGGAA S40 AATGCAATAT GTCATCTGAT GGATCAGAGC ATAGTTTAGA AGGACAAAAA TTTCCACTTG 600 AGATGCAAAT CTACTGCTTT GATGCGGACC GATTTTCAAG TTTTGAGGAA GCAGTCAAAG 660 GAAAAGGGAA GTTAAGAGCT TTATCCATTT TGTTTGAGGT TGGGACAGAA GAAAATTTGG 720 ATTTCAAAGC GATTATTGAT GGAGTCGAAA GTGTTAGTCG TTTTGGGAAG CAGGCTGCTT 780 TAGATCCATT CATACTGTTG AACCTTCTGC CAAACTCAAC TGACAAGTAT TACATTTACA 840 ATGGCTCATT GACATCTCCT CCCTGCACAG ACACAGTTGA CTGGATTGTT TTTAAAGATA 900 CAGTTAGCAT CTCTGAAAGC CAGTTGGCTG TTTTTTGTGA AGTTCTTACA ATGCAACAAT 960 CTGGTTATGT CATGCTGATG GACTACTTAC AAAACAATTT TCGAGAGCAA CAGTACAAGT 1020 TCTCTAGACA GGTGTTTTCC TCATACACTG GAAAGGAAGA GATTCATGAA GCAGTTTGTA 1080 GTTCAGAACC AGAAAATGTT CAGGCTGACC CAGAGAATTA TACCAGCCTT CTTGTTACAT 1140 GGGAAAGACC TCGAGTCGTT TATGATACCA TGATTGAGAA GTTTGCAGTT TTCTACCAGC 1200 AGTTGGATGG AGAGGACCAA ACCAAGCATG AATTTTTGAC AGATGGCTAT CAAGACTTGG 1260 GTGCTATTCT CAATAATTTG CTACCCAATA TGAGTTATGT TCTTCAGATA GTAGCCATAT 1320 GCACTAATGG CTTATATGGA AAATACAGCG ACCAACTGAT TGTCGACATG CCTACTGATA 1380 ATCCTGAACT TGATCTTTTC CCTGAATTAA TTGGAACTGA AGAAATAATC AAGGAGGAGG 1440 AAGAGGGAAA AGACATTGAA GAAGGCGCTA TTGTGAATCC TGGTAGAGAC AGTGCTACAA 1500 ACCAAATCAG GAAAAAGGAA CCCCAGATTT CTACCACAAC ACACTACAAT CGCATAGGGA 1560 CGAAATACAA TGAAGCCAAG ACTAACCGAT CCCCAACAAG AGGAAGTGAA TTCTCTGGAA 1620 AGGGTGATGT TCCCAATACA TCTTTAAATT CCACTTCCCA ACCAGTCACT AAATTAGCCA 1680 CAGAAAAAGA TATTTCCTTG ACTTCTCAGA CTGTGACTGA ACTGCCACCT CACACTGTGG 1740 AAGGTACTTC AGCCTCTTTA AATGATGGCT CTAAAACTGT TCTTAGATCT CCACATATGA 1800 ACTTGTCGGG GACTGCAGAA TCCTTAAATA CAGTTTCTAT AACAGAATAT GAGGAGGAGA 1860 GTTTATTGAC CAGTTTCAAG CTTGATACTG GAGCTGAAGA TTCTTCAGGC TCCAGTCCCG 1920 CAACTTCTGC TATCCCATTC ATCTCTGAGA ACATATCCCA AGGGTATATA TTTTCCTCCG 1980 AAAACCCAGA GACAATAACA TATGATGTCC TTATACCAGA ATCTGCTAβA AATGCTTCCG 2040 AAGATTCAAC TTCATCAGGT TCAGAAGAAT CACTAAAGGA TCCTTCTATG GAGGGAAATG 2100 TGTGGTTTCC TAGCTCTACA GACATAACAG CACAGCCCGA TGTTGGATCA GGCAGAGAGA 2160 GCTTTCTCCA GACTAATTAC ACTGAGATAC GTGTTGATGA ATCTGAGAAG ACAACCAAGT 2220 CCTTTTCTGC AGGCCCAGTG ATGTCACAGG GTCCCTCAGT TACAGATCTG GAAATGCCAC 2280 ATTATTCTAC CTTTGCCTAC TTCCCAACTG AGGTAACACC TCATGCTTTT ACCCCATCCT 2340 CCAGACAACA GGATTTGGTC TCCACGGTCA ACGTGGTATA CTCGCAGACA ACCCAACCGG 2400 TATACAATGA GGCCAGTAAT AGTAGCCATG AGTCTCGTAT TGGTCTAGCT GAGGGGTTGG 2460 AATCCGAGAA GAAβGCAGTT ATACCCCTTG TGATCGTGTC AGCCCTGACT TTTATCTGTC 2520 TAGTGGTTCT TGTGGGTATT CTCATCTACT GGAGGAAATG CTTCCAGACT GCACACTTTT 2580 ACTTAGAGGA CAGTACATCC CCTAGAGTTA TATCCACACC TCCAACACCT ATCTTTCCAA 2640 TTTCAGATGA TGTCGGAGCA ATTCCAATAA AGCACTTTCC AAAGCATGTT GCAGATTTAC 2700 ATGCAAGTAG TGGGTTTACT GAAGAATTTG AGACACTGAA AGAGTTTTAC CAGGAAGTGC 2760 AGAGCTGTAC TGTTGACTTA GGTATTACAG CAGACAGCTC CAACCACCCA GACAACAAGC 2820 ACAAGAATCG ATACATAAAT ATCGTTGCCT ATGATCATAG CAGGGTTAAG CTAGCACAGC 2880 TTGCTGAAAA GGATGGCAAA CTGACTGATT ATATCAATGC CAATTATGTT GATGGCTACA 2940 ACAGACCAAA AGCTTATATT GCTGCCCAAG GCCCACTGAA ATCCACAGCT GAAGATTTCT 3000 GGAGAATGAT ATGGGAACAT AATGTGGAAG TTATTGTCAT GATAACAAAC CTCGTGGAGA 3060 AAGGAAGGAG AAAATGTGAT CAGTACTGGC CTGCCGATGG GAGTGAGGAG TACGGGAACT 3120 TTCTGGTCAC TCAGAAGAGT GTGCAAGTGC TTGCCTATTA TACTGTGAGG AATTTTACTC 3180 TAAGAAACAC AAAAATAAAA AAGGGCTCCC AGAAAGGAAG ACCCAGTGGA CGTGTGGTCA 3240 CACAGTATCA CTACACGCAG TGGCCTGACA TGGGAGTACC AGAGTACTCC CTGCCAGTGC 3300 TGACCTTTGT GAGAAAGGCA GCCTATGCCA AGCGCCATGC AGTGGGGCCT GTTGTCGTCC 3360 ACTGCAGTGC TGGAGTTGGA AGAACAGGCA CATATATTGT GCTAGACAGT ATGTTGCAGC 3420 AGATTCAACA CGAAGGAACT GTCAACATAT TTGGCTTCTT AAAACACATC CGTTCACAAA 3480 GAAATTATTT GGTACAAACT GAGGAGCAAT ATGTCTTCAT TCATGATACA CTGGTTGAGG 3540 CCATACTTAG TAAAGAAACT GAGGTGCTGG ACAGTCATAT TCATGCCTAT GTTAATGCAC 3600 TCCTCATTCC TGGACCAGCA GGCAAAACAA AGCTAGAGAA ACAATTCCAG CTCCTGAGCC 3660 AGTCAAATAT ACAGCAGAGT GACTATTCTG CAGCCCTAAA GCAATGCAAC AGGGAAAAGA 3720 ATCGAACTTC TTCTATCATC CCTGTGGAAA GATCAAGGGT TGGCATTTCA TCCCTGAGTG 3780 GAGAAGGCAC AGACTACATC AATGCCTCCT ATATCATGGG CTATTACCAG AGCAATGAAT 3840 TCATCATTAC CCAGCACCCT CTCCTTCATA CCATCAAGGA TTTCTGGAGG ATGATATGGG 3900 ACCATAATGC CCAACTGGTG GTTATGATTC CTGATGGCCA AAACATGGCA GAAGATGAAT 3960 TTGTTTACTG GCCAAATAAA GATGAGCCTA TAAATTGTGA GAGCTTTAAG GTCACTCTTA 4020 TGGCTGAAGA ACACAAATGT CTATCTAATG AGGAAAAACT TATAATTCAG GACTTTATCT 4080 TAGAAGCTAC ACAGGATGAT TATGTACTTG AAGTGAGGCA CTTTCAGTGT CCTAAATGGC 4140
CAAATCCAGA TAGCCCCATT AGTAAAACTT TTGAACTTAT AAGTGTTATA AAAGAAGAAG 4200
CTGCCAATAG GGATGGGCCT ATGATTGTTC ATGATGAGCA TGGAGGAGTG ACGGCAGGAA 4260
CTTTCTGTGC TCTGACAACC CTTATGCACC AACTAGAAAA AGAAAATTCC GTGGATGTTT 4320
ACCAGGTAGC CAAGATGATC AATCTGATGA GGCCAGGAGT CTTTGCTGAC ATTGAGCAGT 4380
ATCAGTTTCT CTACAAAGTG ATCCTCAGCC TTGTGAGCAC AAGGCAGGAA GAGAATCCAT 4440
CCACCTCTCT GGACAGTAAT GGTGCAGCAT TGCCTGATGG AAATATAGCT GAGAGCTTAG 4500
AGTCTTTAGT TTAACACAGA AAGGGGTGGG GGGACTCACA TCTGAGCATT GTTTTCCTCT 4560
TCCTAAAATT AGGCAGGAAA ATCAGTCTAG TTCTGTTATC TGTTGATTTC CCATCACCTG 4620
10 ACAGTAACTT TCATGACATA GGATTCTGCC GCCAAATTTA TATCATTAAC AATGTGTGCC 4680
TTTTTGCAAG ACTTGTAATT TACTTATTAT GTTTGAACTA AAATGATTGA ATTTTACAGT 4740
ATTTCTAAGA ATGGAATTGT GGTATTTTTT TCTGTATTGA TTTTAACAGA AAATTTCAAT 4800
TTATAGAGGT TAGGAATTCC AAACTACAGA AAATGTTTGT TTTTAGTGTC AAATTTTTAG 4860
CTGTATTTGT AGCAATTATC AGGTTTGCTA GAAATATAAC TTTTAATACA GTAGCCTGTA 4920
15 AATAAAACAC TCTTCCATAT GATATTCAAC ATTTTACAAC TGCAGTATTC ACCTAAAGTA 4980
GAAATAATCT GTTACTTATT GTAAATACTG CCCTAGTGTC TCCATGGACC AAATTTATAT 5040
TTATAATTGT AGATTTTTAT ATTTTACTAC TGAGTCAAGT TTTCTAGTTC TGTGTAATTG 5100
TTTAGTTTAA TGACGTAGTT CATTAGCTGG TCTTACTCTA CCAGTTTTCT GACATTGTAT 5160
TGTGTTACCT AAGTCATTAA CTTTGTTTCA GCATGTAATT TTAACTTTTG TGGAAAATAG 5220
20 AAATACCTTC ATTTTGAAAG AAGTTTTTAT GAGAATAACA CCTTACCAAA CATTGTTCAA 5280
ATGGTTTTTA TCCAAGGAAT TGCAAAAATA AATATAAATA TTGCCATTAA AAAAAAAAAA 5340 AAAAAAAAAA AAAAAAAAAA AAA
Seq ID NO: 378 Protein sequence: 2.D Protein Accession #: EOS sequence
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MVFKASKITF HWGKCNMSSD GSEHSLEGQK FPLEMQIYCF DADRFSSFEE AVKGKGKLRA 60
30 LSILFEVGTE ENLDFKAIID GVESVSRFGK QAALDPFILL NLLPNSTDKY YIYNGSLTSP 120
PCTDTVDWIV FKDTVSISES QLAVFCEVLT MQQSGYVMLM DYLQNNFREQ QYKFSRQVFS 180
SYTGKEEIHE AVCSSEPENV QADPENYTSL LVTWERPR YDTMIEKFAV LYQQLDGEDQ 240
TKHEFLTDGY QDLGAILNNL LPNMSYVLQI VAICTNGLYG KYSDQLIVDM PTDNPELDLF 300
PELIGTEEII KEEEEGKDIE EGAIVNPGRD SATNQIRKKE PQISTTTHYN RIGTKYNEAK 360
35 TNRSPTRGSE FSGKGDVPNT SLNSTΞQPVT KLATEKDISL TSQTVTELPP HTVEGTSASL 420
NDGSKTVLRS PHMNLΞGTAE SLNTVSITEY EEESLLTSFK LDTGAEDSSG SSPATSAIPF 480
ISENISQGYI FSSENPETIT YDVLIPESAR NASEDSTSSG SEESLKDPSM EGNVWFPSST 540
DITAQPDVGS GRESFLQTNY TEIRVDESEK TTKSFSAGPV MSQGPSVTDL EMPHYSTFAY 600
FPTEVTPHAF TPSSRQQDLV STVNWYSQT TQPVYNEASN SSHESRIGLA EGLESEKKAV 660
40 IPLVIVSALT FICLWLVGI LIYWRKCFQT AHFYLEDSTS PRVISTPPTP IFPISDDVGA 720
IPIKHFPKHV ADLHASSGFT EEFETLKEFY QEVQSCTVDL GITADSSNHP DNKHKNRYIN 780
IVAYDHSRVK LAQLAEKDGK LTDYINANYV DGYNRPKAYI AAQGPLKSTA EDFWRMIWEH 840
NVEVIVMITN LVEKGRRKCD QYWPADGSEE YGNFLVTQKS VQVLAYYTVR NFTLRNTKIK 900
KGSQKGRPSG R TQYHYTQ WPDMGVPEYS LPVLTFVRKA AYAKRHAVGP VWHCSAGVG 960
45 RTGTYIVLDS MLQQIQHEGT VNIFGFLKHI RSQRNYLVQT EEQYVFIHDT LVEAILSKET 1020
EVLDSHIHAY VNALLIPGPA GKTKLEKQFQ LLSQSNIQQS DYSAALKQCN REKNRTSSII 1080
PVERSRVGIS SLSGEGTDYI NASYIMGYYQ SNEFIITQHP LLHTIKDFWR MIWDHNAQLV 1140
VMIPDGQNMA EDEFVYWPNK DEPINCESFK VTLMAEEHKC LSNEEKLIIQ DFILEATQDD 1200
YVLEVRHFQC PKWPNPDSPI SKTFELISVI KEEAANRDGP MIVHDEHGGV TAGTFCALTT 1260
50 LMHQLEKENS VDVYQVAKMI NLMRPGVFAD IEQYQFLYKV ILSLVSTRQE ENPSTSLDSN 1320 GAALPDGNIA ESLESLV
Seq ID NO: 379 DNA sequence Nucleic Acid Accession ft: EOS sequence 55 Coding sequence: 148-4632
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CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60
60 CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120
CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AACGTTTCCT CGCTTGCATT 180
CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300
AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360
65 CAAGTAAATG TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420
AACACATTCA TTCATAACAC TGGGAAAACA GTGGAAATTA ATCTCACTAA TGACTACCGT 480
GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AGATAACTTT TCACTGGGGA 540
AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600
GAGATGCAAA TCTACTGCTT TGATGCGGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660
70 GGAAAAGGGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720
GATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780
TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840
AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900
ACAGTTAGCA TCTCTGAAAG CCAGTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960
75 TCTGGTTATG TCATGCTGAT GGACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020
TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGGAAG AGATTCATGA AGCAGTTTGT 1080
AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140
TGGGAAAGAC CTCGAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAG 1200
CAGTTGGATG GAGAGGACCA AACCAAGCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260
80 GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAGAT AGTAGCCATA 1320
TGCACTAATG GCTTATATGG AAAATACAGC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380
AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440
GAAGAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTGGTAGAGA CAGTGCTACA 1500
AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAGGG 1560 ACGAAATACA ATCAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGGA 1620
AAGGGTGATG TTCCCAA AC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680
ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740
GAAGGTACTT CAGCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800
AACTTGTCGG GGACTGCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAG 1860
AGTTTATTGA CCAGTTTCAA GCTTGATACT GGAGCTGAAG ATTCTTCAGG CTCCAGTCCC 1920
GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGβGTATAT ATTTTCCTCC 1980
GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG AAATGCTTCC 2040
GAAGATTCAA CTTCATCAGG TTCAGAAGAA TCACTAAAGG ATCCTTCTAT GGAGGGAAAT 2100
GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AGGCAGAGAG 2160
AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAG 2220
TCCTTTTCTG CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280
CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340
TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400
GTATACAATG AGGCCAGTAA TAGTAGCCAT GAGTCTCGTA TTGGTCTAGC TGAGGGGTTG 2460
GAATCCGAGA AGAAGGCAGT TATACCCCTT GTGATCGTGT CAGCCCTGAC TTTTATCTGT 2520
CTAGTGGTTC TTGTGGGTAT TCTCATCTAC TGGAGGAAAT GCTTCCAGAC TGCACACTTT 2580
TACTTAGAGG ACAGTACATC CCCTAGAGTT ATATCCACAC CTCCAACACC TATCTTTCCA 2640
ATTTCAGATG ATGTCGGAGC AATTCCAATA AAGCACTTTC CAAAGCATGT TGCAGATTTA 2700
CATGCAAGTA GTGGGTTTAC TGAAGAATTT GAGACACTGA AAGAGTTTTA CCAGGAAGTG 2760
CAGAGCTGTA CTGTTGACTT AGGTATTACA GCAGACAGCT CCAACCACCC AGACAACAAG 2820
CACAAGAATC GATACATAAA TATCGTTGCC TATGATCATA GCAGGGTTAA GCTAGCACAG 2880
CTTGCTGAAA AGGATGGCAA ACTGACTGAT TATATCAATβ CCAATTATGT TGATGGCTAC 2940
AACAGACCAA AAGCTTATAT TGCTGCCCAA GGCCCACTGA AATCCACAGC TGAAGATTTC 3000
TGGAGAATGA TATGGGAACA TAATGTGGAA GTTATTGTCA TGATAACAAA CCTCGTGGAG 3060
AAAGGAAGGA GAAAATGTGA TCAGTACTGG CCTGCCGATG GGAGTGAGGA GTACGGGAAC 3120
TTTCTGGTCA CTCAGAAGAG TGTGCAAGTG CTTGCCTATT ATACTGTGAG GAATTTTACT 3180
CTAAGAAACA CAAAAATAAA AAAGGGCTCC CAGAAAGGAA GACCCAGTGG ACGTGTGGTC 3240
ACACAGTATC ACTACACGCA GTGGCCTGAC ATGGGAGTAC CAGAGTACTC CCTGCCAGTG 3300
CTGACCTTTG TGAGAAAGGC AGCCTATGCC AAGCGCCATG CAGTGGGGCC TGTTGTCGTC 3360
CACTGCAGTG CTGGAGTTGG AAGAACAGGC ACATATATTG TGCTAGACAG TATGTTGCAG 3420
CAGATTCAAC ACGAAGGAAC TGTCAACATA TTTGGCTTCT TAAAACACAT CCGTTCACAA 3480
AGAAATTATT TGGTACAAAC TGAGGAGCAA TATGTCTTCA TTCATGATAC ACTGGTTGAG 3540
GCCATACTTA GTAAAGAAAC TGAGGTGCTG GACAGTCATA TTCATGCCTA TGTTAATGCA 3600
CTCCTCATTC CTGGACCAGC AGGCAAAACA AAGCTAGAGA AACAATTCCA GGGTCTCACT 3660
CTGTCACCCA GGCTGGAGTG CAGAGGCACA ATCTCGGCTC ACTGCAACCT TCCTCTCCCT 3720
GGCTTAACTG ATCCTCCTAC CTCAGCCTCC CGAGTGGCTG GGACTATACT CCTGAGCCAG 3780
TCAAATATAC AGCAGAGTGA CTATTCTGCA GCCCTAAAGC AATGCAACAG GGAAAAGAAT 3840
CGAACTTCTT CTATCATCCC TGTGGAAAGA TCAAGGGTTG GCATTTCATC CCTGAGTGGA 3900
GAAGGCACAG ACTACATCAA TGCCTCCTAT ATCATGGGCT ATTACCAGAG CAATGAATTC 3960
ATCATTACCC AGCACCCTCT CCTTCATACC ATCAAGGATT TCTGGAGGAT GATATGGGAC 4020
CATAATGCCC AACTGGTGGT TATGATTCCT GATGGCCAAA ACATGGCAGA AGATGAATTT 4080
GTTTACTGGC CAAATAAAGA TGAGCCTATA AATTGTGAGA GCTTTAAGGT CACTCTTATG 4140
GCTGAAGAAC ACAAATGTCT ATCTAATGAG GAAAAACTTA TAATTCAGGA CTTTATCTTA 4200
GAAGCTACAC AGGATGATTA TGTACTTGAA GTGAGGCACT TTCAGTGTCC TAAATGGCCA 4260
AATCCAGATA GCCCCATTAG TAAAACTTTT GAACTTATAA GTGTTATAAA AGAAGAAGCT 4320
GCCAATAGGG ATGGGCCTAT GATTGTTCAT GATGAGCATG GAGGAGTGAC GGCAGGAACT 4380
TTCTGTGCTC TGACAACCCT TATGCACCAA CTAGAAAAAG AAAATTCCGT GGATGTTTAC 4440
CAGGTAGCCA AGATGATCAA TCTGATGAGG CCAGGAGTCT TTGCTGACAT TGAGCAGTAT 4500
CAGTTTCTCT ACAAAGTGAT CCTCAGCCTT GTGGGCACAA GGCAGGAAGA GAATCCATCC 4560
ACCTCTCTGG ACAGTAATGG TGCAGCATTG CCTGATGGAA ATATAGCTGA GAGCTTAGAG 4620
TCTTTAGTTT AACACAGAAA GGGGTGGGGG GACTCACATC TGAGCATTGT TTTCCTCTTC 4680
CTAAAATTAG GCAGGAAAAT CAGTCTAGTT CTGTTATCTG TTGATTTCCC ATCACCTGAC 4740
AGTAACTTTC ATGACATAGG ATTCTGCCGC CAAATTTATA TCATTAACAA TGTGTGCCTT 4800
TTTGCAAGAC TTGTAATTTA CTTATTATGT TTGAACTAAA ATGATTGAAT TTTACAGTAT 4860
TTCTAAGAAT GGAATTGTGG TATTTTTTTC TGTATTGATT TTAACAGAAA ATTTCAATTT 4920
ATAGAGGTTA GGAATTCCAA ACTACAGAAA ATGTTTGTTT TTAGTGTCAA ATTTTTAGCT 4980
GTATTTGTAG CAATTATCAG GTTTGCTAGA AATATAACTT TTAATACAGT AGCCTGTAAA 5040
TAAAACACTC TTCCATATGA TATTCAACAT TTTACAACTG CAGTATTCAC CTAAAGTAGA 5100
AATAATCTGT TACTTATTGT AAATACTGCC CTAGTGTCTC CATGGACCAA ATTTATATTT 5160
ATAATTGTAG ATTTTTATAT TTTACTACTG AGTCAAGTTT TCTAGTTCTG TGTAATTGTT 5220
TAGTTTAATG ACGTAGTTCA TTAGCTGGTC TTACTCTACC AGTTTTCTGA CATTGTATTG 5280
TGTTACCTAA GTCATTAACT TTGTTTCAGC ATGTAATTTT AACTTTTGTG GAAAATAGAA 5340
ATACCTTCAT TTTGAAAGAA GTTTTTATGA GAATAACACC TTACCAAACA TTGTTCAAAT 5400
GGTTTTTATC CAAGGAATTG CAAAAATAAA TATAAATATT GCCATTAAAA AAAAAAAAAA 5460 AAAAAAAAAA AAAAAAAAAA A
Seq ID NO: 380 Protein sequence: Protein Accession ft: EOS sequence
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I I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNEASNSS HESRIGLAEG LESEKKAVIP 780
LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR VISTPPTPIF PISDDVGAIP 840
IKHFPKHVAD LHASSGFTEE FETLKEFYQE VQSCTVDLGI TADSSNHPDN KHKNRYINIV 900
AYDHSRVKLA QLAEKDGKLT DYINANYVDG YNRPKAYIAA QGPLKSTAED FWRMIWEHNV 960
EVIVMITNLV EKGRRKCDQY WPADGSEEYG NFLVTQKSVQ VLAYYTVRNF TLRNTKIKKG 1020
SQKGRPSGRV VTQYHYTQWP DMGVPEYSLP VLTFVRKAAY AKRHAVGPW VHCSAGVGRT 1080
GTYIVLDSML QQIQHEGTVN IFGFLKHIRS QRNYLVQTEE QYVFIHDTLV EAILSKETEV 1140
LDSHIHAYVN ALLIPGPAGK TKLEKQFQGL TLSPRLECRG TISAHCNLPL PGLTDPPTSA 1200
SRVAGTILLS QSNIQQSDYS AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS 1260
YIMGYYQSNE FIITQHPLLH TIKDFWRMIW DHNAQLWMI PDGQNMAEDE FVYWPNKDEP 1320
INCESFKVTL MAEEHKCLSN EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT 1380
FELISVIKEE AANRDGPMIV HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM 1440
RPGVFADIEQ YQFLYKVILS LVGTRQEENP STSLDSNGAA LPDGNIAESL ESLV
Seq ID NO: 381 DNA sequence
Nucleic Acid Accession # : NM_002851.1 Coding sequence : 148 . .7092
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CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60 CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120 CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180 CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240 CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300 AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360 CAAGTAAATG TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420 AACACATTCA TTCATAACAC TGGGAAAACA GTGGAAATTA ATCTCACTAA TGACTACCGT 480 GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AGATAACTTT TCACTGGGGA 540 AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600 GAGATGCAAA TCTACTGCTT TGATGCGGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660 GGAAAAGGGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720 GATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780 TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840 AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900 ACAGTTAGCA TCTCTGAAAG CCAGTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960 TCTGGTTATG TCATGCTGAT GGACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020 TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGGAAG AGATTCATGA AGCAGTTTGT 1080 AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140 TGGGAAAGAC CTCGAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAG 1200 CAGTTGGATG GAGAGGACCA AACCAAGCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260 GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAGAT AGTAGCCATA 1320 TGCACTAATG GCTTATATGG AAAATACAGC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380 AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440 GAAGAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTGGTAGAGA CAGTGCTACA 1500 AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAGGG 1560 ACGAAATACA ATGAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGGA 1620 AAGGGTGATG TTCCCAATAC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680 ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740 GAAGGTACTT CAGCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800 AACTTGTCGG GGACTGCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAG 1860 AGTTTATTGA CCAGTTTCAA GCTTGATACT GGAGCTGAAG ATTCTTCAGG CTCCAGTCCC 1920 GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGGGTATAT ATTTTCCTCC 1980 GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG .AAATGCTTCC 2040 GAAGATTCAA CTTCATCAGG TTCAGAAGAA TCACTAAAGG ATCCTTCTAT GGAGGGAAAT 2100 GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AGGCAGAGAG 2160 AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAG 2220 TCCTTTTCTG CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280 CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340 TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400 GTATACAATG GTGAGACACC TCTTCAACCT TCCTACAGTA GTGAAGTCTT TCCTCTAGTC 2460 ACCCCTTTGT TGCTTGACAA TCAGATCCTC AACACTACCC CTGCTGCTTC AAGTAGTGAT 2520 TCGGCCTTGC ATGCTACGCC TGTATTTCCC AGTGTCGATG TGTCATTTGA ATCCATCCTG 2580 TCTTCCTATG ATGGTGCACC TTTGCTTCCA TTTTCCTCTG CTTCCTTCAG TAGTGAATTG 2640 TTTCGCCATC TGCATACAGT TTCTCAAATC CTTCCACAAG TTACTTCAGC TACCGAGAGT 2700 GATAAGGTGC CCTTGCATGC TTCTCTGCCA GTGGCTGGGG GTGATTTGCT ATTAGAGCCC 2760 AGCCTTGCTC AGTATTCTGA TGTGCTGTCC ACTACTCATG CTGCTTCAGA GACGCTGGAA 2820 TTTGGTAGTG AATCTGGTGT TCTTTATAAA ACGCTTATGT TTTCTCAAGT TGAACCACCC 2880 AGCAGTGATG CCATGATGCA TGCACGTTCT TCAGGGCCTG AACCTTCTTA TGCCTTGTCT 2940 GATAATGAGG GCTCCCAACA CATCTTCACT GTTTCTTACA GTTCTGCAAT ACCTGTGCAT 3000 GATTCTGTGG GTGTAACTTA TCAGGGTTCC TTATTTAGCG GCCCTAGCCA TATACCAATA 3060 CCTAAGTCTT CGTTAATAAC CCCAACTGCA TCATTACTGC AGCCTACTCA TGCCCTCTCT 3120 GGTGATGGGG AATGGTCTGG AGCCTCTTCT GATAGTGAAT TTCTTTTACC TGACACAGAT 3180 GGGCTGACAG CCCTTAACAT TTCTTCACCT GTTTCTGTAG CTGAATTTAC ATATACAACA 3240 TCTGTGTTTG GTGATGATAA TAAGGCGCTT TCTAAAAGTG AAATAATATA TGGAAATGAG 3300 ACTGAACTGC AAATTCCTTC TTTCAATGAG ATGGTTTACC CTTCTGAAAG CACAGTCATG 3360 CCCAACATGT ATGATAATGT AAATAAGTTG AATGCGTCTT TACAAGAAAC CTCTGTTTCC 3420 ATTTCTAGCA CCAAGGGCAT GTTTCCAGGG TCCCTTGCTC ATACCACCAC TAAGGTTTTT 3480 GATCATGAGA TTAGTCAAGT TCCAGAAAAT AACTTTTCAβ TTCAACCTAC ACATACTGTC 3540 TCTCAAGCAT CTGGTGACAC TTCGGTTAAA CCTGTGCTTA GTGCAAACTC AGAGCCAGCA 3600 TCCTCTGACC CTGCTTCTAG TGAAATGTTA TCTCCTTCAA CTCAGCTCTT ATTTTATGAG 3660 ACCTCAGCTT CTTTTAGTAC TGAAGTATTG CTACAACCTT CCTTTCAGGC TTCTGATGTT 3720 GACACCTTGC TTAAAACTGT TCTTCCAGCT GTGCCCAGTβ ATCCAATATT GGTTGAAACC 3780 CCCAAAGTTG ATAAAATTAG TTCTACAATG TTGCATCTCA TTGTATCAAA TTCTGCTTCA 3840
AGTGAAAACA TGCTGCACTC TACATCTGTA CCAGTTTTTG ATGTGTCGCC TACTTCTCAT 3900
ATGCACTCTG CTTCACTTCA AGGTTTGACC ATTTCCTATG CAAGTGAGAA ATATGAACCA 3960
GTTTTGTTAA AAAGTGAAAG TTCCCACCAA GTGGTACCTT CTTTGTACAG TAATGATGAG 4020
TTGTTCCAAA CGGCCAATTT GGAGATTAAC CAGGCCCATC CCCCAAAAGG AAGGCATGTA 4080
TTTGCTACAC CTGTTTTATC AATTGATGAA CCATTAAATA CACTAATAAA TAAGCTTATA 4140
CATTCCGATG AAATTTTAAC CTCCACCAAA AGTTCTGTTA CTGGTAAGGT ATTTGCTGGT 4200
ATTCCAACAG TTGCTTCTGA TACATTTGTA TCTACTGATC ATTCTGTTCC TATAGGAAAT 4260
GGGCATGTTG CCATTACAGC TGTTTCTCCC CACAGAGATG GTTCTGTAAC CTCAACAAAG 4320
TTGCTGTTTC CTTCTAAGGC AACTTCTGAG CTGAGTCATA GTGCCAAATC TGATGCCGGT 4380
TTAGTGGGTG GTGGTGAAGA TGGTGACACT GATGATGATG GTGATGATGA TGATGACAGA 4440
GATAGTGATG GCTTATCCAT TCATAAGTGT ATGTCATGCT CATCCTATAG AGAATCACAG 4500
GAAAAGGTAA TGAATGATTC AGACACCCAC GAAAACAGTC TTATGGATCA GAATAATCCA 4560
ATCTCATACT CACTATCTGA GAATTCTGAA GAAGATAATA GAGTCACAAG TGTATCCTCA 4620
GACAGTCAAA CTGGTATGGA CAGAAGTCCT GGTAAATCAC CATCAGCAAA TGGGCTATCC 4680
CAAAAGCACA ATGATGGAAA AGAGGAAAAT GACATTCAGA CTGGTAGTGC TCTGCTTCCT 4740
CTCAGCCCTG AATCTAAAGC ATGGGCACTT CTGACAAGTG ATGAAGAAAβ TGGATCAGGG 4800
CAAGGTACCT CAGATAGCCT TAATGAGAAT GAGACTTCCA CAGATTTCAG TTTTGCAGAC 4860
ACTAATGAAA AAGATGCTGA TGGGATCCTG GCAGCAGGTG ACTCAGAAAT AACTCCTGGA 4920
TTCCCACAGT CCCCAACATC ATCTGTTACT AGCGAGAACT CAGAAGTGTT CCACGTTTCA 4980
GAGGCAGAGG CCAGTAATAG TAGCCATGAG TCTCGTATTG GTCTAGCTGA GGGGTTGGAA 5040
TCCGAGAAGA AGGCAGTTAT ACCCCTTGTG ATCGTGTCAG CCCTGACTTT TATCTGTCTA 5100
GTGGTTCTTG TGGGTATTCT CATCTACTGG AGGAAATGCT TCCAGACTGC ACACTTTTAC 5160
TTAGAGGACA GTACATCCCC TAGAGTTATA TCCACACCTC CAACACCTAT CTTTCCAATT 5220
TCAGATGATG TCGGAGCAAT TCCAATAAAG CACTTTCCAA AGCATGTTGC AGATTTACAT 5280
GCAAGTAGTG GGTTTACTGA AGAATTTGAG ACACTGAAAG AGTTTTACCA GGAAGTGCAG 5340
AGCTGTACTG TTGACTTAGG TATTACAGCA GACAGCTCCA ACCACCCAGA CAACAAGCAC 5400
AAGAATCGAT ACATAAATAT CGTTGCCTAT GATCATAGCA GGGTTAAGCT AGCACAGCTT 5460
GCTGAAAAGG ATGGCAAACT GACTGATTAT ATCAATGCCA ATTATGTTGA TGGCTACAAC 5520
AGACCAAAAG CTTATATTGC TGCCCAAGGC CCACTGAAAT CCACAGCTGA AGATTTCTGG 5580
AGAATGATAT GGGAACATAA TGTGGAAGTT ATTGTCATGA TAACAAACCT CGTGGAGAAA 5640
GGAAGGAGAA AATGTGATCA GTACTGGCCT GCCGATGGGA GTGAGGAGTA CGGGAACTTT 5700
CTGGTCACTC AGAAGAGTGT GCAAGTGCTT GCCTATTATA CTGTGAGGAA TTTTACTCTA 5760
AGAAACACAA AAATAAAAAA GGGCTCCCAG AAAGGAAGAC CCAGTGGACG TGTGGTCACA 5820
CAGTATCACT ACACGCAGTG GCCTGACATG GGAGTACCAG AGTACTCCCT GCCAGTGCTG 5880
ACCTTTGTGA GAAAGGCAGC CTATGCCAAG CGCCATGCAG TGGGGCCTGT TGTCGTCCAC 5940
TGCAGTGCTG GAGTTGGAAG AACAGGCACA TATATTGTGC TAGACAGTAT GTTGCAGCAG 6000
ATTCAACACG AAGGAACTGT CAACATATTT GGCTTCTTAA AACACATCCG TTCACAAAGA 6060
AATTATTTGG TACAAACTGA GGAGCAATAT GTCTTCATTC ATGATACACT GGTTGAGGCC 6120
ATACTTAGTA AAGAAACTGA GGTGCTGGAC AGTCATATTC ATGCCTATGT TAATGCACTC 6180
CTCATTCCTG GACCAGCAGG CAAAACAAAG CTAGAGAAAC AATTCCAGCT CCTGAGCCAG 6240
TCAAATATAC AGCAGAGTGA CTATTCTGCA GCCCTAAAGC AATGCAACAG GGAAAAGAAT 6300
CGAACTTCTT CTATCATCCC TGTGGAAAGA TCAAGGGTTG GCATTTCATC CCTGAGTGGA 6360
GAAGGCACAG ACTACATCAA TGCCTCCTAT ATCATGGGCT ATTACCAGAG CAATGAATTC 6420
ATCATTACCC AGCACCCTCT CCTTCATACC ATCAAGGATT TCTGGAGGAT GATATGGGAC 6480
CATAATGCCC AACTGGTGGT TATGATTCCT GATGCCCAAA ACATGGCAβA AGATGAATTT 6540
GTTTACTGGC CAAATAAAGA TGAGCCTATA AATTGTGAGA GCTTTAAGGT CACTCTTATG 6600
GCTGAAGAAC ACAAATGTCT ATCTAATGAG GAAAAACTTA TAATTCAGGA CTTTATCTTA 6660
GAAGCTACAC AGGATGATTA TGTACTTGAA GTGAGGCACT TTCAGTGTCC TAAATGGCCA 6720
AATCCAGATA GCCCCATTAG TAAAACTTTT GAACTTATAA GTGTTATAAA AGAAGAAGCT 6780
GCCAATAGGG ATGGGCCTAT GATTGTTCAT GATGAGCATG GAGGAGTGAC GGCAGGAACT 6840
TTCTGTGCTC TGACAACCCT TATGCACCAA CTAGAAAAAG AAAATTCCGT GGATGTTTAC 6900
CAGGTAGCCA AGATGATCAA TCTGATGAGG CCAGGAGTCT TTGCTGACAT TGAGCAGTAT 6960
CAGTTTCTCT ACAAAGTGAT CCTCAGCCTT GTGAGCACAA GGCAGGAAGA GAATCCATCC 7020
ACCTCTCTGG ACAGTAATGG TGCAGCATTG CCTGATGGAA ATATAGCTGA GAGCTTAGAG 7080
TCTTTAGTTT AACACAGAAA GGGGTGGGGG GACTCACATC TGAGCATTGT TTTCCTCTTC 7140
CTAAAATTAG GCAGGAAAAT CAGTCTAGTT CTGTTATCTG TTGATTTCCC ATCACCTGAC 7200
AGTAACTTTC ATGACATAGG ATTCTGCCGC CAAATTTATA TCATTAACAA TGTGTGCCTT 7260
TTTGCAAGAC TTGTAATTTA CTTATTATGT TTGAACTAAA ATGATTGAAT TTTACAGTAT 7320
TTCTAAGAAT GGAATTGTGG TATTTTTTTC TGTATTGATT TTAACAGAAA ATTTCAATTT 7380
ATAGAGGTTA GGAATTCCAA ACTACAGAAA ATGTTTGTTT TTAGTGTCAA ATTTTTAGCT 7440
GTATTTGTAG CAATTATCAG GTTTGCTAGA AATATAACTT TTAATACAGT AGCCTGTAAA 7500
TAAAACACTC TTCCATATGA TATTCAACAT TTTACAACTG CAGTATTCAC CTAAAGTAGA 7560
AATAATCTGT TACTTATTGT AAATACTGCC CTAGTGTCTC CATGGACCAA ATTTATATTT 7620
ATAATTGTAG ATTTTTATAT TTTACTACTG AGTCAAGTTT TCTAGTTCTG TGTAATTGTT 7680
TAGTTTAATG ACGTAGTTCA TTAGCTGGTC TTACTCTACC AGTTTTCTGA CATTGTATTG 7740
TGTTACCTAA GTCATTAACT TTGTTTCAGC ATGTAATTTT AACTTTTGTG GAAAATAGAA 7800
ATACCTTCAT TTTGAAAGAA GTTTTTATGA GAATAACACC TTACCAAACA TTGTTCAAAT 7860
GGTTTTTATC CAAGGAATTG CAAAAATAAA TATAAATATT GCCATTAAAA AAAAAAAAAA 7920 AAAAAAAAAA AAAAAAAAAA A
Seq ID NO : 382 Protein sequence Protein Accession ft : NP 002842 .1
11 21 31 41 51
I I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNGETPLQ PSYSSEVFPL VTPLLLDNQI 780 LNTTPAASSS DSALHATPVF PSVDVSFESI LSSYDGAPLL PFSSASFSSE LFRHLHTVSQ 840 ILPQVTSATE SDKVPLHASL PVAGGDLLLE PSLAQYSDVL STTHAASETL EFGSESGVLY 900 KTLMFSQVEP PSSDAMMHAR SSGPEPSYAL SDNEGSQHIF TVSYSSAIPV HDSVGVTYQG 960 SLFSGPSHIP IPKSSLITPT ASLLQPTHAL SGDGEWSGAS SDSEFLLPDT DGLTALNISS 1020 PVSVAEFTYT TSVFGDDNKA LSKSEIIYGN ETELQIPSFN EMVYPSESTV MPNMYDNVNK 1080 LNASLQETSV SISSTKGMFP GSLAHTTTKV FDHEISQVPE NNFSVQPTHT VSQASGDTSL 1140 KPVLSANSEP ASSDPASSEM LSPSTQLLFY ETSASFSTEV LLQPSFQASD VDTLLKTVLP 1200 AVPSDPILVE TPKVDKISST MLHLIVSNSA SSENMLHSTS VPVFDVSPTS HMHSASLQGL 1260 TISYASEKYE PVLLKSESSH Q PSLYSND ELFQTANLEI NQAHPPKGRH VFATPVLSID 1320 EPLNTLINKL IHSDEILTST KSSVTGKVFA GIPTVASDTF VSTDHSVPIG NGHVAITAVS 1380 PHRDGSVTST KLLFPSKATS ELSHSAKSDA GLVGGGEDGD TDDDGDDDDD RDSDGLSIHK 1440 CMSCSSYRES QEKVMNDSDT HENSLMDQNN PISYSLSENS EEDNRVTSVS SDSQTGMDRS 1500 PGKSPSANGL SQKHNDGKEE NDIQTGSALL PLSPESKAWA VLTSDEESGS GQGTSDSLNE 1S60 NETSTDFSFA DTNEKDADGI LAAGDSEITP GFPQSPTSSV TSENSEVFHV SEAEASNSSH 1620 ESRIGLAEGL ESEKKAVIPL VIVSALTFIC LWLVGILIY WRKCFQTAHF YLEDSTSPRV 1680 ISTPPTPIFP ISDDVGAIPI KHFPKHVADL HASSGFTEEF ETLKEFYQEV QSCTVDLGIT 1740 ADSSNHPDNK HKNRYINIVA YDHSRVKLAQ LAEKDGKLTD YINANYVDGY NRPKAYIAAQ 1800 GPLKSTAEDF WRMIWEHNVE VIVMITNLVE KGRRKCDQYW PADGSEEYGN FLVTQKSVQV 1860 LAYYTVRNFT LRNTKIKKGS QKGRPSGRW TQYHYTQWPD MGVPEYSLPV LTFVRKAAYA 1920 KRHAVGPVW HCSAGVGRTG TYIVLDSMLQ QIQHECTVNI FGFLKHIRSQ RNYLVQTEEQ 1980 YVFIHDTLVE AILSKETEVL DSHIHAYVNA LLIPGPAGKT KLEKQFQLLS QSNIQQSDYS 2040 AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS YIMGYYQSNE FIITQHPLLH 2100 TIKDFWRMIW DHNAQLWMI PDGQNMAEDE FVYWPNKDEP INCESFKVTL MAEEHKCLSN 2160 EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT FELISVIKEE AANRDGPMIV 2220 HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM RPGVFADIEQ YQFLYKVILS 2280 LVSTRQEENP STSLDSNGAA LPDGNIAESL ESLV
Seq ID NO: 383 DNA sequence Nucleic Acid Accession #: NM_005688.1 Coding sequence: 126..4439
11 21 31 41 51
CCGGGCAGGT GGCTCATGCT CGGGAGCGTG GTTGAGCGGC TGGCGCGGTT GTCCTGGAGC 60
AGGGGCGCAG GAATTCTGAT GTGAAACTAA CAGTCTGTGA GCCCTGGAAC CTCCGCTCAG 120
AGAAGATGAA GGATATCGAC ATAGGAAAAG AGTATATCAT CCCCA6TCCT GGGTATAGAA 180
GTGTGAGGGA GAGAACCAGC ACTTCTGGGA CGCACAGAGA CCGTGAAGAT TCCAAGTTCA 240
GGAGAACTCG ACCGTTGGAA TGCCAAGATG CCTTGGAAAC AGCAGCCCGA GCCGAGGGCC 300
TCTCTCTTGA TGCCTCCATG CATTCTCAGC TCAGAATCCT GGATGAGGAG CATCCCAAGG 360
GAAAGTACCA TCATGGCTTG AGTGCTCTGA AGCCCATCCG GACTACTTCC AAACACCAGC 420
ACCCAGTGGA CAATGCTGGG CTTTTTTCCT GTATGACTTT TTCGTGGCTT TCTTCTCTGG 480
CCCGTGTGGC CCACAAGAAG GGGGAGCTCT CAATGGAAGA CGTGTGGTCT CTGTCCAAGC 540
ACGAGTCTTC TGACGTGAAC TGCAGAAGAC TAGAGAGACT GTGGCAAGAA GAGCTGAATG 600
AAGTTGGGCC AGACGCTGCT TCCCTGCGAA GGGTTGTGTG GATCTTCTGC CGCACCAGGC 660
TCATCCTGTC CATCGTGTGC CTGATGATCA CGCAGCTGGC TGGCTTCAGT GGACCAGCCT 720
TCATGGTGAA ACACCTCTTG GAGTATACCC AGGCAACAGA GTCTAACCTG CAGTACAGCT 780
TGTTGTTAGT GCTGGGCCTC CTCCTGACGG AAATCGTGCG GTCTTGGTCG CTTGCACTGA 840
CTTGGGCATT GAATTACCGA ACCGGTGTCC GCTTGCGGGG GGCCATCCTA ACCATGGCAT 900
TTAAGAAGAT CCTTAAGTTA AAGAACATTA AAGAGAAATC CCTGGGTGAG CTCATCAACA 960
TTTGCTCCAA CGATGGGCAG AGAATGTTTG AGGCAGCAGC CGTTGGCAGC CTGCTGGCTG 1020
GAGGACCCGT TGTTGCCATC TTAGGCATGA TTTATAATGT AATTATTCTG GGACCAACAG 1080
GCTTCCTGGG ATCAGCTGTT TTTATCCTCT TTTACCCAGC AATGATGTTT GCATCACGGC 1140
TCACAGCATA TTTCAGGAGA AAATGCGTGG CCGCCACGGA TGAACGTGTC CAGAAGATGA 1200
ATGAAGTTCT TACTTACATT AAATTTATCA AAATGTATGC CTGGGTCAAA GCATTTTCTC 1260
AGAGTGTTCA AAAAATCCGC GAGGAGGAGC GTCGGATATT GGAAAAAGCC GGGTACTTCC 1320
AGGGTATCAC TGTGGGTGTG GCTCCCATTG TGGTGGTGAT TGCCAGCGTG GTGACCTTCT 1380
CTGTTCATAT GACCCTGGGC TTCGATCTGA CAGCAGCACA GGCTTTCACA GTGGTGACAG 1440
TCTTCAATTC CATGACTTTT GCTTTGAAAG TAACACCGTT TTCAGTAAAG TCCCTCTCAG 1500
AAGCCTCAGT GGCTGTTGAC AGATTTAAGA GTTTGTTTCT AATGGAAGAG GTTCACATGA 1560
TAAAGAACAA ACCAGCCAGT CCTCACATCA AGATAGAGAT GAAAAATGCC ACCTTGGCAT 1620
GGGACTCCTC CCACTCCAGT ATCCAGAACT CGCCCAAGCT GACCCCCAAA ATGAAAAAAG 1680
ACAAGAGGGC TTCCAGGGGC AAGAAAGAGA AGGTGAGGCA GCTGCAGCGC ACTGAGCATC 1740
AGGCGGTGCT GGCAGAGCAG AAAGGCCACC TCCTCCTGGA CAGTGACGAG CGGCCCAGTC 1800
CCGAAGAGGA AGAAGGCAAG CACATCCACC TGGGCCACCT GCGCTTACAG AGGACACTGC 1860
ACAGCATCGA TCTGGAGATC CAAGAGGGTA AACTGGTTGG AATCTGCGGC AGTGTGGGAA 1920
GTGGAAAAAC CTCTCTCATT TCAGCCATTT TAGGCCAGAT GACGCTTCTA GAGGGCAGCA 1980
TTGCAATCAG TGGAACCTTC GCTTATGTGG CCCAGCAGGC CTGGATCCTC AATGCTACTC 2040
TGAGAGACAA CATCCTGTTT GGGAAGGAAT ATGATGAAGA AAGATACAAC TCTGTGCTGA 2100
ACAGCTGCTG CCTGAGGCCT GACCTGGCCA TTCTTCCCAG CAGCGACCTG ACGGAGATTG 2160
GAGAGCGAGG AGCCAACCTG AGCGGTGGGC AGCGCCAGAG GATCAGCCTT GCCCGGGCCT 2220
TGTATAGTGA CAGGAGCATC TACATCCTGG ACGACCCCCT CAGTGCCTTA GATGCCCATG 2280
TGGGCAACCA CATCTTCAAT AGTGCTATCC GGAAACATCT CAAGTCCAAG ACAGTTCTGT 2340
TTGTTACCCA CCAGTTACAG TACCTGGTTG ACTGTGATGA AGTGATCTTC ATGAAAGAGG 2400
GCTGTATTAC GGAAAGAGGC ACCCATGAGG AACTGATGAA TTTAAATGGT GACTATGCTA 2460
CCATTTTTAA TAACCTGTTG CTGGGAGAGA CACCGCCAGT TGAGATCAAT TCAAAAAAGG 2520
AAACCAGTGG TTCACAGAAG AAGTCACAAG ACAAGGGTCC TAAAACAGGA TCAGTAAAGA 2580
AGGAAAAAGC AGTAAAGCCA GAGGAAGGGC AGCTTGTGCA GCTGGAAGAG AAAGGGCAGG 2640
GTTCAGTGCC CTGGTCAGTA TATGGTGTCT ACATCCAGGC TGCTGGGGGC CCCTTGGCAT 2700
TCCTGGTTAT TATGGCCCTT TTCATGCTGA ATGTAGGCAG CACCGCCTTC AGCACCTGGT 2760 GGTTGAGTTA CTGGATCAAG CAAGGAAGCG GGAACACCAC TGTGACTCGA GGGAACGAGA 2820 CCTCGGTGAG TGACAGCATG AAGGACAATC CTCATATGCA GTACTATGCC AGCATCTACG 2880 CCCTCTCCAT GGCAGTCATG CTGATCCTGA AAGCCATTCG AGGAGTTGTC TTTGTCAAGG 2940 GCACGCTGCG AGCTTCCTCC CGGCTGCATG ACGAGCTTTT CCGAAGGATC CTTCGAAGCC 3000 CTATGAAGTT TTTTGACACG ACCCCCACAG GGAGGATTCT CAACAGGTTT TCCAAAGACA 3060 TGGATGAAGT TGACGTGCGG CTGCCGTTCC AGGCCGAGAT GTTCATCCAG AACGTTATCC 3120 TGGTGTTCTT CTGTGTGGGA ATGATCGCAG GAGTCTTCCC GTGGTTCCTT GTGGCAGTGG 3180 GGCCCCTTGT CATCGTCTTT TCAGTCCTGC ACATTGTCTC CAGGGTCCTG ATTCGGGAGC 3240 TGAAGCGTCT GGACAATATC ACGCAGTCAC CTTTCCTCTC CCACATCACG TCCAGCATAC 3300 AGGGCCTTGC CACCATCCAC GCCTACAATA AAGGGCAGGA GTTTCTGCAC AGATACCAGG 3360 AGCTGCTGGA TGACAACCAA GCTCCTTTTT TTTTGTTTAC GTGTGCGATG CGGTGGCTGG 3420 CTGTGCGGCT GGACCTCATC AGCATCGCCC TCATCACCAC CACGGGGCTG ATGATCGTTC 3480 TTATGCACGG GCAGATTCCC CCAGCCTATG CβGGTCTCGC CATCTCTTAT GCTGTCCAGT 3540 TAACGGGGCT GTTCCAGTTT ACGGTCAGAC TGGCATCTGA GACAGAAGCT CGATTCACCT 3600 CGGTGGAGAG GATCAATCAC TACATTAAGA CTCTGTCCTT GGAAGCACCT GCCAGAATTA 3660 AGAACAAGGC TCCCTCCCCT GACTGGCCCC AGGAGGGAGA GGTGACCTTT GAGAACGCAG 3720 AGATGAGGTA CCGAGAAAAC CTCCCTCTTG TCCTAAAGAA AGTATCCTTC ACGATCAAAC 3780 CTAAAGAGAA GATTGGCATT GTGGGGCGGA CAGGATCAGG GAAGTCCTCG CTGGGGATGG 3840 CCCTCTTCCG TCTGGTGGAG TTATCTGGAG GCTGCATCAA GATTGATGGA GTGAGAATCA 3900 GTGATATTGG CCTTGCCGAC CTCCGAAGCA AACTCTCTAT CATTCCTCAA GAGCCGCTGC 3960 TGTTCAGTGG CACTGTCAGA TCAAATTTGG ACCCCTTCAA CCAGTACACT GAAGACCAGA 4020 TTTGGGATGC CCTGGAGAGG ACACACATGA AAGAATGTAT TGCTCAGCTA CCTCTGAAAC 4080 TTGAATCTGA AGTGATGGAG AATGGGGATA ACTTCTCAGT GGGGGAACGG CAGCTCTTGT 4140 GCATAGCTAG AGCCCTGCTC CGCCACTGTA AGATTCTGAT TTTAGATGAA GCCACAGCTG 4200 CCATGGACAC AGAGACAGAC TTATTGATTC AAGAGACCAT CCGAGAAGCA TTTGCAGACT 4260 GTACCATGCT GACCATTGCC CATCGCCTGC ACACGGTTCT AGGCTCCGAT AGGATTATGG 4320 TGCTGGCCCA GGGACAGGTG GTGGAGTTTG ACACCCCATC GGTCCTTCTG TCCAACGACA 4380 GTTCCCGATT CTATGCCATG TTTGCTGCTG CAGAGAACAA GGTCGCTGTC AAGGGCTGAC 4440 TCCTCCCTGT TGACGAAGTC TCTTTTCTTT AGAGCATTGC CATTCCCTGC CTGGGGCGGG 4500 CCCCTCATCG CGTCCTCCTA CCGAAACCTT GCCTTTCTCG ATTTTATCTT TCGCACAGCA 4560 GTTCCGGATT GGCTTGTGTG TTTCACTTTT AGGGAGAGTC ATATTTTGAT TATTGTATTT 4620 ATTCCATATT CATGTAAACA AAATTTAGTT TTTGTTCTTA ATTGCACTCT AAAAGGTTCA 4680 GGGAACCGTT ATTATAATTG TATCAGAGGC CTATAATGAA GCTTTATACG TGTAGCTATA 4740 TCTATATATA ATTCTGTACA TAGCCTATAT TTACAGTGAA AATGTAAGCT GTTTATTTTA 4800 TATTAAAATA AGCACTGTGC TAATAACAGT GCATATTCCT TTCTATCATT TTTGTACAGT 4860 TTGCTGTACT AGAGATCTGG TTTTGCTATT AGACTGTAGG AAGAGTAGCA TTTCATTCTT 4920 CTCTAGCTGβ TGGTTTCACG GTGCCAGGTT TTCTGGGTGT CCAAAGGAAG ACGTGTGGCA 4980 ATAGTGGGCC CTCCGACAGC CCCCTCTGCC GCCTCCCCAC AGCCGCTCCA GGGGTGGCTG 5040 GAGACGGGTG GGCGGCTGGA GACCATGCAG AGCGCCGTGA GTTCTCAGGG CTCCTGCCTT 5100 CTGTCCTGGT GTCACTTACT GTTTCTGTCA GGAGAGCAGC GGGGCGAAGC CCAGGCCCCT 5160 TTTCACTCCC TCCATCAAGA ATGGGGATCA CAGAGACATT CCTCCGAGCC GGGGAGTTTC 5220 TTTCCTGCCT TCTTCTTTTT GCTGTTGTTT CTAAACAAGA ATCAGTCTAT CCACAGAGAG 5280 TCCCACTGCC TCAGGTTCCT ATGGCTGGCC ACTGCACAGA GCTCTCCAGC TCCAAGACCT 5340 GTTGGTTCCA AGCCCTGGAG CCAACTGCTG CTTTTTGAGG TGGCACTTTT TCATTTGCCT 5400 ATTCCCACAC CTCCACAGTT CAGTGGCAGG GCTCAGGATT TCGTGGGTCT GTTTTCCTTT 5460 CTCACCGCAG TCGTCGCACA GTCTCTCTCT CTCTCTCCCC TCAAAGTCTβ CAACTTTAAG 5520 CAGCTCTTGC TAATCAGTGT CTCACACTGG CGTAGAAGTT TTTGTACTGT AAAGAGACCT 5580 ACCTCAGGTT GCTGGTTGCT GTGTGGTTTG GTGTGTTCCC GCAAACCCCC TTTGTGCTGT 5640 GGGGCTGGTA GCTCAGGTGG GCGTGGTCAC TGCTGTCATC AGTTGAATGG TCAGCGTTGC 5700 ATGTCGTGAC CAACTAGACA TTCTGTCGCC TTAGCATGTT TGCTGAACAC CTTGTGGAAG 5760 CAAAAATCTG AAAATGTGAA TAAAATTATT TTGGATTTTG TAAAAAAAAA AAAAAAAAAA 5820 AAAAAAAAAA AAAAAAAA
Seq ID NO: 384 Protein sequence Protein Accession ft: NP_005679.1
11 21 31 41 51
I I I I I
MKDIDIGKEY IIPSPGYRSV RERTSTSGTH RDREDSKFRR TRPLECQDAL ETAARAEGLS 60' LDASMHSQLR ILDEEHPKGK YHHGLSALKP IRTTSKHQHP VDNAGLFSCM TFSWLSSLAR 120 VAHKKGELSM EDVWSLSKHE SSDVNCRRLE RLWQEELNEV GPDAASLRRV VWIFCRTRLI 180 LSIVCLMITQ LAGFSGPAFM VKHLLEYTQA TESNLQYSLL LVLGLLLTEI VRSWSLALTW 240 ALNYRTGVRL RGAILTMAFK KILKLKNIKE KSLGELINIC SNDGQRMFEA AAVGSLLAGG 300 PWAILGMIY NVIILGPTGF LGSAVFILFY PAMMFASRLT AYFRRKCVAA TDERVQKMNE 360 VLTYIKFIKM YAWVKAFSQS VQKIREEERR ILEKAGYFQG ITVGVAPIW VIASWTFSV 420 HMTLGFDLTA AQAFTWTVF NSMTFALKVT PFSVKSLSEA SVAVDRFKSL FLMEEVHMIK 480 NKPASPHIKI EMKNATLAWD SSHSSIQNSP KLTPKMKKDK RASRGKKEKV RQLQRTEHQA 540 VLAEQKGHLL LDSDERPSPE EEEGKHIHLG HLRLQRTLHS IDLEIQEGKL VGICGSVGSG 600 KTSLISAILG QMTLLEGSIA ISGTFAYVAQ QAWILNATLR DNILFGKEYD EERYNSVLNS 660 CCLRPDLAIL PSSDLTEIGE RGANLSGGQR QRISLARALY SDRSIYILDD PLSALDAHVG 720 NHIFNSAIRK HLKSKTVLFV THQLQYLVDC DEVIFMKEGC ITERGTHEEL MNLNGDYATI 780 FNNLLLGETP PVEINSKKET SGSQKKSQDK GPKTGSVKKE KAVKPEEGQL VQLEEKGQGS 840 VPWSVYGVYI QAAGGPLAFL VIMALFMLNV GSTAFSTWWL SYWIKQGSGN TTVTRGNETS 900 VSDSMKDNPH MQYYASIYAL SMAVMLILKA IRGWFVKGT LRASSRLHDE LFRRILRSPM 960 KFFDTTPTGR ILNRFSKDMD EVDVRLPFQA EMFIQNVILV FFCVGMIAGV FPWFLVAVGP 1020 LVILFSVLHI VSRVLIRELK RLDNITQSPF LSHITSSIQG LATIHAYNKG QEFLHRYQEL 1080 LDDNQAPFFL FTCAMRWLAV RLDLISIALI TTTGLMIVLM HGQIPPAYAG LAISYAVQLT 1140 GLFQFTVRLA SETEARFTSV ERINHYIKTL SLEAPARIKN KAPSPDWPQE GEVTFENAEM 1200 RYRENLPLVL KKVSFTIKPK EKIGIVGRTG SGKSSLGMAL FRLVELSGGC IKIDGVRISD 1260 IGLADLRSKL SIIPQEPVLF SGTVRSNLDP FNQYTEDQIW DALERTHMKE CIAQLPLKLE 1320 SEVMENGDNF SVGERQLLCI ARALLRHCKI LILDEATAAM DTETDLLIQE TIREAFADCT 1380 MLTIAHRLHT VLGSDRIMVL AQGQWEFDT PSVLLSNDSS RFYAMFAAAE NKVAVKG Seq ID NO: 385 DNA sequence
Nucleic Acid Accession ft: NM_001327.1
Coding sequence: 89..631
11 21 31 41 51
AGCAGGGGGC GCTGTGTGTA CCGAGAATAC GAGAATACCT CGTGGGCCCT GACCTTCTCT 60 CTGAGAGCCG GGCAGAGGCT CCGGAGCCAT GCAGGCCGAA GGCCGGGGCA CAGGGGGTTC 120 GACGGGCGAT GCTGATGGCC CAGGAGGCCC TGGCATTCCT GATGGCCCAG GGGGCAATGC 180 0 TGGCGGCCCA GGAGAGGCGG GTGCCACGGG CGGCAGAGGT CCCCGGGGCG CAGGGGCAGC 240 AAGGGCCTCG GGGCCGGGAG GAGGCGCCCC GCGGGGTCCG CATGGCGGCG CGGCTTCAGG 300 GCTGAATGGA TGCTGCAGAT GCGGGGCCAG GGGGCCGGAG AGCCGCCTGC TTGAGTTCTA 360 CCTCGCCATG CCTTTCGCGA CACCCATGGA AGCAGAGCTG GCCCGCAGGA GCCTGGCCCA 420 GGATGCCCCA CCGCTTCCCG TGCCAGGGGT GCTTCTGAAG GAGTTCACTG TGTCCGGCAA 480
15 CATACTGACT ATCCGACTGA CTGCTGCAGA CCACCGCCAA CTGCAGCTCT CCATCAGCTC 540 CTGTCTCCAG CAGCTTTCCC TGTTGATGTG GATCACGCAG TGCTTTCTGC CCGTGTTTTT 600 GGCTCAGCCT CCCTCAGGGC AGAGGCGCTA AGCCCAGCCT GGCGCCCCTT CCTAGGTCAT 660 GCCTCCTCCC CTAGGGAATG GTCCCAGCAC GAGTGGCCAG TTCATTGTGG GGGCCTGATT 720 GTTTGTCGCT GGAGGAGGAC GGCTTACATG TTTGTTTCTG TAGAAAATAA AACTGAGCTA 0
Seq ID NO: 386 Protein sequence Protein Accession ft: NP 001318.1
__ 1 11 21 31 41 51
25 i i i i i i
MQAEGRGTGG STGDADGPGG PGIPDGPGGN AGGPGEAGAT GGRGPRGAGA ARASGPGGGA 60 PRGPHGGAAS GLNGCCRCGA RGPESRLLEF YLAMPFATPM EAELARRSLA QDAPPLPVPG 120 VLLKEFTVSG NILTIRLTAA DHRQLQLSIS SCLQQLSLLM WITQCFLPVF LAQPPSGQRR
30 Seq ID NO: 387 DNA sequence
Nucleic Acid Accession #: Eos sequence Coding sequence: 52..459
11 21 31 41 51
35
CCTCGTGGGC C ICTGACCTTC T ICTCTGAGAG C ICGGGCAGAG G ICTCCGGAGC C IATGCAGGCC 60 GAAGGCCAGG GCACAGGGGG TTCGACGGGC GATGCTGATG GCCCAGGAGG CCCTGGCATT 120 CCTGATGGCC CAGGGGGCAA TGCTGGCGGC CCAGGAGAGG CGGGTGCCAC GGGCGGCAGA 180 GGTCCCCGGG GCGCAGGGGC AGCAAGGGCC TCGGGGCCGA GAGGAGGCGC CCCGCGGGGT 240
40 CCGCATGGCG GTGCCGCTTC TGCGCAGGAT GGAAGGTGCC CCTGCGGGGC CAGGAGGCCG 300 GACAGCCGCC TGCTTCAGTT CCGACTGACT GCTGCAGACC ACCGCCAACT GCAGCTCTCC 360 ATCAGCTCCT GTCTCCAGCA GCTTTCCCTG TTGATGTGGA TCACGCAGTG CTTTCTGCCC 420 GTGTTTTTGG CTCAGGCTCC CTCAGGGCAG AGGCGCTAAG CCCAGCCTGG CGCCCCTTCC 480 TAGGTCATGC CTCCTCCCCT AGGGAATGGT CCCAGCACGA GTGGCCAGTT CATTGTGGGG 540
45 GCCTGATTGT TTGTCGCTGG AGGAGGACGG CTTACATGTT TGTTTCTGTA GAAAATAAAG 600 CTGAGCTA
Seq ID NO: 388 Protein sequence Protein Accession #: Eos sequence
50
1 11 21 31 41 51
I I I I I I
MQAEGQGTGG STGDADGPGG PGIPDGPGGN AGGPGEAGAT GGRGPRGAGA ARASGPRGGA 60 PRGPHGGAAS AQDGRCPCGA RRPDSRLLQF RLTAADHRQL QLSISSCLQQ LSLLMWITQC 120
55 FLPVFLAQAP SGQRR
Seq ID NO: 389 DNA sequence
Nucleic Acid Accession #: NM_005562.1
Coding sequence: 90..3671
60
11 21 31 41 51
ACAGCGGAGC GCAGAGTGAG AACCACCAAC CGAGGCGCCG GGCAGCGACC CCTGCAGCGG 60 AGACAGAGAC TGAGCGGCCC GGCACCGCCA TGCCTGCGCT CTGGCTGGGC TGCTGCCTCT 120
65 GCTTCTCGCT CCTCCTGCCC GCAGCCCGGG CCACCTCCAG GAGGGAAGTC TGTGATTGCA 180 ATGGGAAGTC CAGGCAGTGT ATCTTTGATC GGGAACTTCA CAGACAAACT GGTAATGGAT 240 TCCGCTGCCT CAACTGCAAT GACAACACTG ATGGCATTCA CTGCGAGAAG TGCAAGAATG 300 GCTTTTACCG GCACAGAGAA AGGGACCGCT GTTTGCCCTG CAATTGTAAC TCCAAAGGTT 360 CTCTTAGTGC TCGATGTGAC AACTCTGGAC GGTGCAGCTG TAAACCAGGT GTGACAGGAG 420
70 CCAGATGCGA CCGATGTCTG CCAGGCTTCC ACATGCTCAC GGATGCGGGG TGCACCCAAG 480 ACCAGAGACT GCTAGACTCC AAGTGTGACT GTGACCCAGC TGGCATCGCA GGGCCCTGTG 540 ACGCGGGCCG CTGTGTCTGC AAGCCAGCTG TTACTGGAGA ACGCTGTGAT AGGTGTCGAT 600 CAGGTTACTA TAATCTGGAT GGGGGGAACC CTGAGGGCTG TACCCAGTGT TTCTGCTATG 660 GGCATTCAGC CAGCTGCCGC AGCTCTGCAG AATACAGTGT CCATAAGATC ACCTCTACCT 720
75 TTCATCAAGA TGTTGATGGC TGGAAGGCTG TCCAACGAAA TGGGTCTCCT GCAAAGCTCC 780 AATGGTCACA GCGCCATCAA GATGTGTTTA GCTCAGCCCA ACGACTAGAC CCTGTCTATT 840 TTGTGGCTCC TGCCAAATTT CTTGGGAATC AACAGGTGAG CTATGGGCAA AGCCTGTCCT 900 TTGACTACCG TGTGGACAGA GGAGGCAGAC ACCCATCTGC CCATGATGTG ATTCTGGAAG 960 GTGCTGGTCT ACGGATCACA GCTCCCTTGA TGCCACTTGG CAAGACACTG CCTTGTGGGC 1020
80 TCACCAAGAC TTACACATTC AGGTTAAATG AGCATCCAAG CAATAATTGG AGCCCCCAGC 1080 TGAGTTACTT TGAGTATCGA AGGTTACTGC GGAATCTCAC AGCCCTCCGC ATCCGAGCTA 1140 CATATGGAGA ATACAGTACT GGGTACATTG ACAATGTGAC CCTGATTTCA GCCCGCCCTG 1200 TCTCTGGAGC CCCAGCACCC TGGGTTGAAC AGTGTATATG TCCTGTTGGG TACAAGGGGC 1260 AATTCTGCCA GGATTGTGCT TCTGGCTACA AGAGAGATTC AGCGAGACTG GGGCCTTTTG 1320 GCACCTGTAT TCCTTGTAAC TGTCAAGGGG GAGGGGCCTG TGATCCAGAC ACAGGAGATT 1380
GTTATTCAGG GGATGAGAAT CCTGACATTG AGTGTGCTGA CTGCCCAATT GGTTTCTACA 1440
ACGATCCGCA CGACCCCCGC AGCTGCAAGC CATGTCCCTG TCATAACGGG TTCAGCTGCT 1500
CAGTGATGCC GGAGACGGAG GAGGTGGTGT GCAATAACTG CCCTCCCGGG GTCACCGGTG 1560
CCCGCTGTGA GCTCTGTGCT GATGGCTACT TTGGGGACCC CTTTGGTGAA CATGGCCCAG 1620
TGAGGCCTTG TCAGCCCTGT CAATGCAACA ACAATGTGGA CCCCAGTGCC TCTGGGAATT 1680
GTGACCGGCT GACAGGCAGG TGTTTGAAGT GTATCCACAA CACAGCCGGC ATCTACTGCG 1740
ACCAGTGCAA AGCAGGCTAC TTCGGGGACC CATTGGCTCC CAACCCAGCA GACAAGTGTC 1800
GAGCTTGCAA CTGTAACCCC ATGGGCTCAG AGCCTGTAGG ATGTCGAAGT GATGGCACCT 1860
GTGTTTGCAA GCCAGGATTT GGTGGCCCCA ACTGTGAGCA TGGAGCATTC AGCTGTCCAG 1920
CTTGCTATAA TCAAGTGAAG ATTCAGATGG ATCAGTTTAT GCAGCAβCTT CAGAGAATGG 1980
AGGCCCTGAT TTCAAAGGCT CAGGGTGGTG ATGGAGTAGT ACCTGATACA GAGCTGGAAG 2040
GCAGGATGCA GCAGGCTGAG CAGGCCCTTC AGGACATTCT GAGAGATGCC CAGATTTCAG 2100
AAGGTGCTAG CAGATCCCTT GGTCTCCAGT TGGCCAAGGT GAGGAGCCAA GAGAACAGCT 2160
ACCAGAGCCG CCTGGATGAC CTCAAGATGA CTGTGGAAAG AGTTCGGGCT CTGGGAAGTC 2220
AGTACCAGAA CCGAGTTCGG GATACTCACA GGCTCATCAC TCAGATGCAG CTGAGCCTGG 2280
CAGAAAGTGA AGCTTCCTTG GGAAACACTA ACATTCCTGC CTCAGACCAC TACGTGGGGC 2340
CAAATGGCTT TAAAAGTCTG GCTCAGGAGG CCACAAGATT AGCAGAAAGC CACGTTGAGT 2400
CAGCCAGTAA CATGGAGCAA CTGACAAGGG AAACTGAGGA CTATTCCAAA CAAGCCCTCT 2460
CACTGGTGCG CAAGGCCCTG CATGAAGGAG TCGGAAGCGG AAGCGGTAGC CCGGACGGTG 2520
CTGTGGTGCA AGGGCTTGTG GAAAAATTGG AGAAAACCAA GTCCCTGGCC CAGCAGTTGA 2580
CAAGGGAGGC CACTCAAGCG GAAATTGAAG CAGATAGGTC TTATCAGCAC AGTCTCCGCC 2640
TCCTGGATTC AGTGTCTCGG CTTCAGGGAG TCAGTGATCA GTCCTTTCAG GTGGAAGAAG 2700
CAAAGAGGAT CAAACAAAAA GCGGATTCAC TCTCAACGCT GGTAACCAGG CATATGGATG 2760
AGTTCAAGCG TACACAAAAG AATCTGGGAA ACTGGAAAGA AGAAGCACAG CAGCTCTTAC 2820
AGAATGGAAA AAGTGGGAGA GAGAAATCAG ATCAGCTGCT TTCCCGTGCC AATCTTGCTA 2880
AAAGCAGAGC ACAAGAAGCA CTGAGTATGG GCAATGCCAC TTTTTATGAA GTTGAGAGCA 2940
TCCTTAAAAA CCTCAGAGAG TTTGACCTGC AGGTGGACAA CAGAAAAGCA GAAGCTGAAG 3000
AAGCCATGAA GAGACTCTCC TACATCAGCC AGAAGGTTTC AGATGCCAGT GACAAGACCC 3060
AGCAAGCAGA AAGAGCCCTG GGGAGCGCTG CTGCTGATGC ACAGAGGGCA AAGAATGGGG 3120
CCGGGGAGGC CCTGGAAATC TCCAGTGAGA TTGAACAGGA GATTGGGAGT CTGAACTTGG 3180
AAGCCAATGT GACAGCAGAT GGAGCCTTGG CCATGGAAAA GGGACTGGCC TCTCTGAAGA 3240
GTGAGATGAG GGAAGTGGAA GGAGAGCTGG AAAGGAAGGA GCTGGAGTTT GACACGAATA 3300
TGGATGCAGT ACAGATGGTG ATTACAGAAG CCCAGAAGGT TGATACCAGA GCCAAGAACG 3360
CTGGGGTTAC AATCCAAGAC ACACTCAACA CATTAGACGG CCTCCTGCAT CTGATGGACC 3420
AGCCTCTCAG TGTAGATGAA GAGGGGCTGG TCTTACTGGA GCAGAAGCTT TCCCGAGCCA 3480
AGACCCAGAT CAACAGCCAA CTGCGGCCCA TGATGTCAGA GCTGGAAGAG AGGGCACGTC 3540
AGCAGAGGGG CCACCTCCAT TTGCTGGAGA CAAGCATAGA TGGGATTCTG GCTGATGTGA 3600
AGAACTTGGA GAACATTAGG GACAACCTGC CCCCAGGCTG CTACAATACC CAGGCTCTTG 3660
AGCAACAGTG AAGCTGCCAT AAATATTTCT CAACTGAGGT TCTTGGGATA CAGATCTCAG 3720
GGCTCGGGAG CCATGTCATG TGAGTGGGTG GGATGGGGAC ATTTGAACAT GTTTAATGGG 3780
TATGCTCAGG TCAACTGACC TGACCCCATT CCTGATCCCA TGGCCAGGTG GTTGTCTTAT 3840
TGCACCATAC TCCTTGCTTC CTGATGCTGG GCAATGAGGC AGATAGCACT GGGTGTGAGA 3900
ATGATCAAGG ATCTGGACCC CAAAGAATAG ACTGGATGGA AAGACAAACT GCACAGGCAG 3960
ATGTTTGCCT CATAATAGTC GTAAGTGGAG TCCTGGAATT TGGACAAGTG CTGTTGGGAT 4020
ATAGTCAACT TATTCTTTGA GTAATGTGAC TAAAGGAAAA AACTTTGACT TTGCCCAGGC 4080
ATGAAATTCT TCCTAATGTC AGAACAGAGT GCAACCCAGT CACACTGTGG CCAGTAAAAT 4140
ACTATTGCCT CATATTGTCC TCTGCAAGCT TCTTGCTGAT CAGAGTTCCT CCTACTTACA 4200
ACCCAGGGTG TGAACATGTT CTCCATTTTC AAGCTGGAAG AAGTGAGCAG TGTTGGAGTG 4260
AGGACCTGTA AGGCAGGCCC ATTCAGAGCT ATGGTGCTTG CTGGTGCCTG CCACCTTCAA 4320
GTTCTGGACC TGGGCATGAC ATCCTTTCTT TTAATGATGC CATGGCAACT TAGAGATTGC 4380
ATTTTTATTA AAGCATTTCC TACCAGCAAA GCAAATGTTG GGAAAGTATT TACTTTTTCG 4440
GTTTCAAAGT GATAGAAAAG TGTGGCTTGG GCATTGAAAG AGGTAAAATT CTCTAGATTT 4500
ATTAGTCCTA ATTCAATCCT ACTTTTCGAA CACCAAAAAT GATGCGCATC AATGTATTTT 4560
ATCTTATTTT CTCAATCTCC TCTCTCTTTC CTCCACCCAT AATAAGAGAA TGTTCCTACT 4620
CACACTTCAG CTGGGTCACA TCCATCCCTC CATTCATCCT TCCATCCATC TTTCCATCCA 4680
TTACCTCCAT CCATCCTTCC AACATATATT TATTGAGTAC CTACTGTGTG CCAGGGGCTG 4740
GTGGGACAGT GGTGACATAG TCTCTGCCCT CATAGAGTTG ATTGTCTAGT GAGGAAGACA 4800
AGCATTTTTA AAAAATAAAT TTAAACTTAC AAACTTTGTT TGTCACAAGT GGTGTTTATT 4860
GCAATAACCG CTTGGTTTGC AACCTCTTTG CTCAACAGAA CATATGTTGC AAGACCCTCC 4920
CATGGGGGCA CTTGAGTTTT GGCAAGGCTG ACAGAGCTCT GGGTTGTGCA CATTTCTTTG 4980
CATTCCAGCT GTCACTCTGT GCCTTTCTAC AACTGATTGC AACAGACTGT TGAGTTATGA 5040
TAACACCAGT GGGAATTGCT GGAGGAACCA GAGGCACTTC CACCTTGGCT GGGAAGACTA 5100
TGGTGCTGCC TTGCTTCTGT ATTTCCTTGG ATTTTCCTGA AAGTGTTTTT AAATAAAGAA 5160 CAATTGTTAG ATGCC
Seq ID NO: 390 Protein sequence Protein Accession ft: NP 005553.1
11 21 31 41 51
I I I I I I
MPALWLGCCL CFSLLLPAAR ATSRREVCDC NGKSRQCIFD RELHRQTGNG FRCLNCNDNT 60 DGIHCEKCKN GFYRHRERDR CLPCNCNSKG SLSARCDNSG RCSCKPGVTG ARCDRCLPGF 120 HMLTDAGCTQ DQRLLDSKCD CDPAGIAGPC DAGRCVCKPA VTGERCDRCR SGYYNLDGGN 180 PEGCTQCFCY GHSASCRSSA EYSVHKITST FHQDVDGWKA VQRNGSPAKL QWSQRHQDVF 240 SSAQRLDPVY FVAPAKFLGN QQVSYGQSLS FDYRVDRGGR HPSAHDVILE GAGLRITAPL 300 MPLGKTLPCG LTKTYTFRLN EHPSNNWSPQ LSYFEYRRLL RNLTALRIRA TYGEYSTGYI 360 DNVTLISARP VSGAPAPWVE QCICPVGYKG QFCQDCASGY KRDSARLGPF GTCIPCNCQG 420 GGACDPDTGD CYSGDENPDI ECADCPIGFY NDPHDPRSCK PCPCHNGFSC SVMPETEEW 480 CNNCPPGVTG ARCELCADGY FGDPFGEHGP VRPCQPCQCN NNVDPSASGN CDRLTGRCLK 540 CIHNTAGIYC DQCKAGYFGD PLAPNPADKC RACNCNPMGS EPVGCRSDGT CVCKPGFGGP 600 NCEHGAFSCP ACYNQVKIQM DQFMQQLQRM EALISKAQGG DGWPDTELE GRMQQAEQAL 660 QDILRDAQIS EGASRSLGLQ LAKVRSQENS YQSRLDDLKM TVERVRALGS QYQNRVRDTH 720 RLITQMQLSL AESEASLGNT NIPASDHYVG PNGFKSLAQE ATRLAESHVE SASNMEQLTR 780 ETEDYSKQAL SLVRKALHEG VGSGSGSPDG AWQGLVEKL EKTKSLAQQL TREATQAEIE 840 ADRSYQHSLR LLDSVSRLQG VSDQSFQVEE AKRIKQKADS LSTLVTRHMD EFKRTQKNLG 900 NWKEEAQQLL QNGKSGREKS DQLLSRANLA KSRAQEALSM GNATFYEVES ILKNLREFDL 960 QVDNRKAEAE EAMKRLSYIΞ QKVSDASDKT QQAERALGSA AADAQRAKNG AGEALEISSE 1020 IEQEIGSLNL EANVTADGAL AMEKGLASLK SEMREVEGEL ERKELEFDTN MDAVQMVITE 1080 AQKVDTRAKN AGVTIQDTLN TLDGLLHLMD QPLSVDEEGL VLLEQKLSRA KTQINSQLRP 1140 MMSELEERAR QQRGHLHLLE TSIDGILADV KNLENIRDNL PPGCYNTQAL EQQ
Seq ID NO: 391 DNA sequence Nucleic Acid Accession if: AF101051.1 Coding sequence: 221.856
11 21 31 41 51
I
GAGCAACCTC AGCTTCTAGT ATCCAGACTC CAGCGCCGCC CCGGGCGCGG ACCCCAACCC 60
CGACCCAGAG CTTCTCCAGC GGCGGCGCAG CGAGCAGGGC TCCCCGCCTT AACTTCCTCC 120
GCGGGGCCCA GCCACCTTCG GGAGTCCGGG TTGCCCACCT GCAAACTCTC CGCCTTCTGC 180
ACCTGCCACC CCTGAGCCAG CGCGGGCGCC CGAGCGAGTC ATGGCCAACG CGGGGCTGCA 240
GCTGTTGGGC TTCATTCTCG CCTTCCTGGG ATGGATCGGC GCCATCGTCA GCACTGCCCT 300
GCCCCAGTGG AGGATTTACT CCTATGCCGG CGACAACATC GTGACCGCCC AGGCCATGTA 360
CGAGGGGCTG TGGATGTCCT GCGTGTCGCA GAGCACCGGG CAGATCCACT GCAAAGTCTT 420
TGACTCCTTG CTGAATCTGA GCAGCACATT GCAAGCAACC CGTGCCTTGA TGGTGGTTGG 480
CATCCTCCTG GGAGTGATAG CAATCTTTGT GGCCACCGTT GGCATGAAGT GTATGAAGTG 540
CTTGGAAGAC GATGAGGTGC AGAAGATGAG GATGGCTGTC ATTGGGGCTG CGATATTTCT 600
TCTTGCAGGT CTGGCTATTT TAGTTGCCAC AGCATGGTAT GGCAATAGAA TCGTTCAAGA 660
ATTCTATGAC CCTATGACCC CAGTCAATGC CAGGTACGAA TTTGGTCAGG CTCTCTTCAC 720
TGGCTGGGCT GCTGCTTCTC TCTGCCTTCT GGGAGGTGCC CTACTTTGCT GTTCCTGTCC 780
CCGAAAAACA ACCTCTTACC CAACACCAAG GCCCTATCCA AAACCTGCAC CTTCCAGCGG 840
GAAAGACTAC GTGTGACACA GAGGCAAAAG GAGAAAATCA TGTTGAAACA AACCGAAAAT 900
GGACATTGAG ATACTATCAT TAACATTAGG ACCTTAGAAT TTTGGGTATT GTAATCTGAA 960
GTATGGTATT ACAAAACAAA CAAACAAACA AAAAACCCAT GTGTTAAAAT ACTCAGTGCT 1020
AAACATGGCT TAATCTTATT TTATCTTCTT TCCTCAATAT AGGAGGGAAG ATTTTACCAT 1080
TTGTATTACT GCTTCCCATT GAGTAATCAT ACTCAAATGG GGGAAGGGGT GCTCCTTAAA 1140
TATATATAGA TATGTATATA TACATGTTTT TCTATTAAAA ATAGACAGTA AAATACTATT 1200
CTCATTATGT TGATACTAGC ATACTTAAAA TATCTCTAAA ATAGGTAAAT GTATTTAATT 1260
CCATATTGAT GAAGATGTTT ATTGGTATAT TTTCTTTTTC GTCCTTATAT ACATATGTAA 1320
CAGTCAAATA TCATTTACTC TTCTTCATTA GCTTTGGGTG CCTTTGCCAC AAGACCTAGC 1380
CTAATTTACC AAGGATGAAT TCTTTCAATT CTTCATGCGT GCCCTTTTCA TATACTTATT 1440
TTATTTTTTA CCATAATCTT ATAGCACTTG CATCGTTATT AAGCCCTTAT TTGTTTTGTG 1500
TTTCATTGGT CTCTATCTCC TGAATCTAAC ACATTTCATA GCCTACATTT TAGTTTCTAA 1560
AGCCAAGAAG AATTTATTAC AAATCAGAAC TTTGGAGGCA AATCTTTCTG CATGACCAAA 1620
GTGATAAATT CCTGTTGACC TTCCCACACA ATCCCTGTAC TCTGACCCAT AGCACTCTTG 1680
TTTGCTTTGA AAATATTTGT CCAATTGAGT AGCTGCATGC TGTTCCCCCA GGTGTTGTAA 1740
CACAACTTTA TTGATTGAAT TTTTAAGCTA CTTATTCATA GTTTTATATC CCCCTAAACT 1800
ACCTTTTTGT TCCCCATTCC TTAATTGTAT TGTTTTCCCA AGTGTAATTA TCATGCGTTT 1860
TATATCTTCC TAATAAGGTG TGGTCTGTTT GTCTGAACAA AGTGCTAGAC TTTCTGGAGT 1920
GATAATCTGG TGACAAATAT TCTCTCTGTA GCTGTAAGCA AGTCACTTAA TCTTTCTACC 1980
TCTTTTTTCT ATCTGCCAAA TTGAGATAAT GATACTTAAC CAGTTAGAAG AGGTAGTGTG 2040
AATATTAATT AGTTTATATT ACTCTCATTC TTTGAACATG AACTATGCCT ATGTAGTGTC 2100
TTTATTTGCT CAGCTGGCTG AGACACTGAA GAAGTCACTG AACAAAACCT ACACACGTAC 2160
CTTCATGTGA TTCACTGCCT TCCTCTCTCT ACCAGTCTAT TTCCACTGAA CAAAACCTAC 2220
ACACATACCT TCATGTGGTT CAGTGCCTTC CTCTCTCTAC CAGTCTATTT CCACTGAACA 2280
AAACCTACGC ACATACCTTC ATGTGGCTCA GTGCCTTCCT CTCTCTACCA GTCTATTTCC 2340
ATTCTTTCAG CTGTGTCTGA CATGTTTGTG CTCTGTTCCA TTTTAACAAC TGCTCTTACT 2400
TTTCCAGTCT GTACAGAATG CTATTTCACT TGAGCAAGAT GATGTATGGA AAGGGTGTTG 2460
GCACTGGTGT CTGGAGACCT GGATTTGAGT CTTGGTGCTA TCAATCACCG TCTGTGTTTG 2520
AGCAAGGCAT TTGGCTGCTG TAAGCTTATT GCTTCATCTG TAAGCGGTGG TTTGTAATTC 2580
CTGATCTTCC CACCTCACAG TGATGTTGTG GGGATCCAGT GAGATAGAAT ACATGTAAGT 2640
GTGGTTTTGT AATTTGAAAA GTGCTATACT AAGGGAAAGA ATTGAGGAAT TAACTGCATA 2700
CGTTTTGGTG TTGCTTTTCA AATGTTTGAA AATAAAAAAA TGTTAAGAAA TGGGTTTCTT 2760
GCCTTAACCA GTCTCTCAAG TGATGAGACA GTGAAGTAAA ATTGAGTGCA CTAAACGAAT 2820
AAGATTCTGA GGAAGTCTTA TCTTCTGCAG TGAGTATGGC CCAATGCTTT CTGTGGCTAA 2880
ACAGATGTAA TGGGAAGAAA TAAAAGCCTA CGTGTTGGTA AATCCAACAG CAAGGGAGAT 2940
TTTTGAATCA TAATAACTCA TAAGGTGCTA TCTGTTCAGT GATGCCCTCA GAGCTCTTGC 3000
TGTTAGCTGG CAGCTGACGC TGCTAGGATA GTTAGTTTGG AAATGGTACT TCATAATAAA 3060
CTACACAAGG AAAGTCAGCC ACCGTGTCTT ATGAGGAATT GGACCTAATA AATTTTAGTG 3120
TGCCTTCCAA ACCTGAGAAT ATATGCTTTT GGAAGTTAAA ATTTAAATGG CTTTTGCCAC 3180
ATACATAGAT CTTCATGATG TGTGAGTGTA ATTCCATGTG GATATCAGTT ACCAAACATT 3240
ACAAAAAAAT TTTATGGCCC AAAATGACCA ACGAAATTGT TACAATAGAA TTTATCCAAT 3300
TTTGATCTTT TTATATTCTT CTACCACACC TGGAAACAGA CCAATAGACA TTTTGGGGTT 3360
TTATAATGGG AATTTGTATA AAGCATTACT CTTTTTCAAT AAATTGTTTT TTAATTTAAA 3420
AAAAGGAAAA AAAAAAAAAA AAA
Seq ID NO : 392 Protein sequence Protein Accesεion # : AAD16433 .1
1 11 21 31 41 51
I I I I I I
MANAGLQLLG FILAFLGWIG AIVSTALPQW RIYSYAGDNI VTAQAMYEGL WMSCVSQSTG 60
QIQCKVFDSL LNLSSTLQAT RALMWGILL GVIAIFVATV GMKCMKCLED DEVQKMRMAV 120
IGGAIFLLAG LAILVATAWY GNRIVQEFYD PMTPVNARYE FGQALFTGWA AASLCLLGGA 180 LLCCSCPRKT TSYPTPRPYP KPAPSSGKDY V Seq ID NO: 393 DNA sequence
Nucleic Acid Accesεion ft: NM_006180.1
Coding εequence: 352..2820
1 11 21 31 41 51
I I I I I I
CCCCCATTCG CATCTAACAA GGAATCTGCG CCCCAGAGAG TCCCGGACGC CGCCGGTCGG 60
TGCCCGGCGC GCCGGGCCAT GCAGCGACGG CCGCCGCGGA GCTCCGAGCA GCGGTAGCGC 120
CCCCCTGTAA AGCGGTTCGC TATGCCGGGA CCACTGTGAA CCCTGCCGCC TGCCGGAACA 180
CTCTTCGCTC CGGACCAGCT CAGCCTCTGA TAAGCTGGAC TCGGCACGCC CGCAACAAGC 240
ACCGAGGAGT TAAGAGAGCC GCAAGCGCAG GGAAGGCCTC CCCGCACGGG TGGGGGAAAG 300
CGGCCGGTGC AGCGCGGGGA CAGGCACTCG GGCTGGCACT GGCTGCTAGG GATGTCGTCC 360
TGGATAAGGT GGCATGGACC CGCCATGGCG CGGCTCTGGG GCTTCTGCTG GCTGGTTGTG 420
GGCTTCTGGA GGGCCGCTTT CGCCTGTCCC ACGTCCTGCA AATGCAGTGC CTCTCGGATC 480
TGGTGCAGCG ACCCTTCTCC TGGCATCGTG GCATTTCCGA GATTGGAGCC TAACAGTGTA 540
GATCCTGAGA ACATCACCGA AATTTTCATC GCAAACCAGA AAAGGTTAGA AATCATCAAC 600
GAAGATGATG TTGAAGCTTA TGTGGGACTG AGAAATCTGA CAATTGTGGA TTCTGGATTA 660
AAATTTGTGG CTCATAAAGC ATTTCTGAAA AACAGCAACC TGCAGCACAT CAATTTTACC 720
CGAAACAAAC TGACGAGTTT GTCTAGGAAA CATTTCCGTC ACCTTGACTT GTCTGAACTG 780
ATCCTGGTGG GCAATCCATT TACATGCTCC TGTGACATTA TGTGGATCAA GACTCTCCAA 840
GAGGCTAAAT CCAGTCCAGA CACTCAGGAT TTGTACTGCC TGAATGAAAG CAGCAAGAAT 900
ATTCCCCTGG CAAACCTGCA GATACCCAAT TGTGGTTTGC CATCTGCAAA TCTGGCCGCA 960
CCTAACCTCA CTGTGGAGGA AGGAAAGTCT ATCACATTAT CCTGTAGTGT GGCAGGTGAT 1020
CCGGTTCCTA ATATGTATTG GGATGTTGGT AACCTGGTTT CCAAACATAT GAATGAAACA 1080
AGCCACACAC AGGGCTCCTT AAGGATAACT AACATTTCAT CCGATGACAG TGGGAAGCAG 1140
ATCTCTTGTG TGGCGGAAAA TCTTGTAGGA GAAGATCAAG ATTCTGTCAA CCTCACTGTG 1200
CATTTTGCAC CAACTATCAC ATTTCTCGAA TCTCCAACCT CAGACCACCA CTGGTGCATT 1260
CCATTCACTG TGAAAGGCAA CCCCAAACCA GCGCTTCAGT GGTTCTATAA CGGGGCAATA 1320
TTGAATGAGT CCAAATACAT CTGTACTAAA ATACATGTTA CCAATCACAC GGAGTACCAC 1380
GGCTGCCTCC AGCTGGATAA TCCCACTCAC ATGAACAATG GGGACTACAC TCTAATAGCC 1440
AAGAATGAGT ATGGGAAGGA TGAGAAACAG ATTTCTGCTC ACTTCATGGG CTGGCCTGGA 1500
ATTGACGATG GTGCAAACCC AAATTATCCT GATGTAATTT ATGAAGATTA TGGAACTGCA 1560
GCGAATGACA TCGGGGACAC CACGAACAGA AGTAATGAAA TCCCTTCCAC AGACGTCACT 1620
GATAAAACCG GTCGGGAACA TCTCTCGGTC TATGCTGTGG TGGTGATTGC GTCTGTGGTG 1680
GGATTTTGCC TTTTGGTAAT GCTGTTTCTG CTTAAGTTGG CAAGACACTC CAAGTTTGGC 1740
ATGAAAGGCC CAGCCTCCGT TATCAGCAAT GATGATGACT CTGCCAGCCC ACTCCATCAC 1800
ATCTCCAATG GGAGTAACAC TCCATCTTCT TCGGAAGGTG GCCCAGATGC TGTCATTATT 1860
GGAATGACCA AGATCCCTGT CATTGAAAAT CCCCAGTACT TTGGCATCAC CAACAGTCAG 1920
CTCAAGCCAG ACACATTTGT TCAGCACATC AAGCGACATA ACATTGTTCT GAAAAGGGAG 1980
CTAGGCGAAG GAGCCTTTGG AAAAGTGTTC CTAGCTGAAT GCTATAACCT CTGTCCTGAG 2040
CAGGACAAGA TCTTGGTGGC AGTGAAGACC CTGAAGGATG CCAGTGACAA TGCACGCAAG 2100
GACTTCCACC GTGAGGCCGA GCTCCTGACC AACCTCCAGC ATGAGCACAT CGTCAAGTTC 2160
TATGGCGTCT GCGTGGAGGG CGACCCCCTC ATCATGGTCT TTGAGTACAT GAAGCATGGG 2220
GACCTCAACA AGTTCCTCAG GGCACACGGC CCTGATGCCG TGCTGATGGC TGAGGGCAAC 2280
CCGCCCACGG AACTGACGCA GTCGCAGATG CTGCATATAG CCCAGCAGAT CGCCGCGGGC 2340
ATGGTCTACC TGGCGTCCCA GCACTTCGTG CACCGCGATT TGGCCACCAG GAACTGCCTG 2400
GTCGGGGAGA ACTTGCTGGT GAAAATCGGG GACTTTGGGA TGTCCCGGGA CGTGTACAGC 2460
ACTGACTACT ACAGGGTCGG TGGCCACACA ATGCTGCCCA TTCGCTGGAT GCCTCCAGAG 2520
AGCATCATGT ACAGGAAATT CACGACGGAA AGCGACGTCT GGAGCCTGGG GGTCGTGTTG 2580
TGGGAGATTT TCACCTATGG CAAACAGCCC TGGTACCAGC TGTCAAACAA TGAGGTGATA 2640
GAGTGTATCA CTCAGGGCCG AGTCCTGCAG CGACCCCGCA CGTGCCCCCA GGAGGTGTAT 2700
GAGCTGATGC TGGGGTGCTG GCAGCGAGAG CCCCACATGA GGAAGAACAT CAAGGGCATC 2760
CATACCCTCC TTCAGAACTT GGCCAAGGCA TCTCCGGTCT ACCTGGACAT TCTAGGCTAG 2820
GGCCCTTTTC CCCAGACCGA TCCTTCCCAA CGTACTCCTC AGACGGGCTG AGAGGATGAA 2880
CATCTTTTAA CTGCCGCTGG AGGCCACCAA GCTGCTCTCC TTCACTCTGA CAGTATTAAC 2940
ATCAAAGACT CCGAGAAGCT CTCGAGGGAA GCAGTGTGTA CTTCTTCATC CATAGACACA 3000
GTATTGACTT CTTTTTGGCA TTATCTCTTT CTCTCTTTCC ATCTCCCTTG GTTGTTCCTT 3060
TTTCTTTTTT TAAATTTTCT TTTTCTTCTT TTTTTTCGTC TTCCCTGCTT CACGATTCTT 3120
ACCCTTTCTT TTGAATCAAT CTGGCTTCTG CATTACTATT AACTCTGCAT AGACAAAGGC 3180
CTTAACAAAC GTAATTTGTT ATATCAGCAG ACACTCCAGT TTGCCCACCA CAACTAACAA 3240
TGCCTTGTTG TATTCCTGCC TTTGATGTGG ATGAAAAAAA GGGAAAACAA ATATTTCACT 3300
TAAACTTTGT CACTTCTGCT GTACAGATAT CGAGAGTTTC TATGGATTCA CTTCTATTTA 3360
TTTATTATTA TTACTGTTCT TATTGTTTTT GGATGGCTTA AGCCTGTGTA TAAAAAAGAA 3420
AACTTGTGTT CAATCTGTGA AGCCTTTATC TATGGGAGAT TAAAACCAGA GAGAAAGAAG 3480
ATTTATTATG AACCGCAATA TGGGAGGAAC AAAGACAACC ACTGGGATCA GCTGGTGTCA 3540
GTCCCTACTT AGGAAATACT CAGCAACTCT TAGCTGGGAA GAATGTATTC GGCACCTTCC 3600
CCTGAGGACC TTTCTGAGGA GTAAAAAGAC TACTGGCCTC TGTGCCATGG ATGATTCTTT 3660
TCCCATCACC AGAAATGATA GCGTGCAGTA GAGAGCAAAG ATGGCTT
Seq ID NO: 394 Protein sequence Protein Accession ft: NP 006171.1
11 21 31 41 51
MSSWIRWHGP A IMARLWGFCW L IWGFWRAAF A ICPTSCKCSA S IRIWCSDPSP G IIVAFPRLEP 60 NSVDPENITE IFIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAHKA FLKNSNLQHI 120 NFTRNKLTSL SRKHFRHLDL SELILVGNPF TCSCDIMWIK TLQEAKSSPD TQDLYCLNES 180 SKNIPLANLQ IPNCGLPSAN LAAPNLTVEE GKSITLSCSV AGDPVPNMYW DVGNLVSKHM 240 NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH 300 WCIPFTVKGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT 360 LIAKNEYGKD EKQISAHFMG WPGIDDGANP NYPDVIYEDY GTAANDIGDT TNRSNEIPST 420 DVTDKTGREH LSVYAVWIA SWGFCLLVM LFLLKLARHS KFGMKGPASV ISNDDDSASP 480 LHHISNGSNT PSSSEGGPDA VIIGMTKIPV IENPQYFGIT NSQLKPDTFV QHIKRHNIVL 540 KRELGEGAFG KVFLAECYNL CPEQDKILVA VKTLKDASDN ARKDFHREAE LLTNLQHEHI 600 VKFYGVCVEG DPLIMVFEYM KHGDLNKFLR AHGPDAVLMA EGNPPTELTQ SQMLHIAQQI 660
AAGMVYLASQ HFVHRDLATR NCLVGENLLV KIGDFGMSRD VYSTDYYRVG GHTMLPIRWM 720
PPESIMYRKF TTESDVWSLG WLWEIFTYG KQPWYQLSNN EVIECITQGR VLQRPRTCPQ 780 EVYELMLGCW QREPHMRKNI KGIHTLLQNL AKASPVYLDI LG
Seq ID NO: 395 DNA sequence Nucleic Acid Accesεion ft: AF410899 Coding sequence: 483..2999
11 21 31 41 51
I I I I I I
GGGAGCAGGA GCCTCGCTGG CTGCTTCGCT CGCGCTCTAC GCGCTCAGTC CCCGGCGGTA 60 GCAGGAGCCT GGACCCAGGC GCCGGCGGCG GGCGTGAGGC GCCGGAGCCC GGCCTCGAGG 120 TGCATACCGG ACCCCCATTC GCATCTAACA AGGAATCTGC GCCCCAGAGA GTCCCGGACG 180 CCGCCβGTCG GTGCCCGGCG CGCCGGGCCA TGCAGCGACG GCCGCCGCGG AGCTCCGAGC 240 AGCGGTAGCG CCCCCCTGTA AAGCGGTTCG CTATGCCGGG ACCACTGTGA ACCCTGCCGC 300 CTGCCGGAAC ACTCTTCGCT CCGGACCAGC TCAGCCTCTG ATAAGCTGGA CTCGGCACGC 360 CCGCAACAAG CACCGAGGAG TTAAGAGAGC CGCAAGCGCA GGGAAGGCCT CCCCGCACGG 420 GTGGGGGAAA GCGGCCGGTG CAGCGCGGGG ACAGGCACTC GGGCTGGCAC TGGCTGCTAG 480 GGATGTCGTC CTGGATAAGG TGGCATGGAC CCGCCATGGC GCGGCTCTGG GGCTTCTGCT 540 GGCTGGTTGT GGGCTTCTGG AGGGCCGCTT TCGCCTGTCC CACGTCCTGC AAATGCAGTG 600 CCTCTCGGAT CTGGTGCAGC GACCCTTCTC CTGGCATCGT GGCATTTCCG AGATTGGAGC 660 CTAACAGTGT AGATCCTGAG AACATCACCG AAATTTTCAT CGCAAACCAG AAAAGGTTAG 720 AAATCATCAA CGAAGATGAT GTTGAAGCTT ATGTGGGACT GAGAAATCTG ACAATTGTGG 780 ATTCTGGATT AAAATTTGTG GCTCATAAAG CATTTCTGAA AAACAGCAAC CTGCAGCACA 840 TCAATTTTAC CCGAAACAAA CTGACGAGTT TGTCTAGGAA ACATTTCCGT CACCTTGACT 900 TGTCTGAACT GATCCTGGTG GGCAATCCAT TTACATGCTC CTGTGACATT ATGTGGATCA 960 AGACTCTCCA AGAGGCTAAA TCCAGTCCAG ACACTCAGGA TTTGTACTGC CTGAATGAAA 1020 GCAGCAAGAA TATTCCCCTG GCAAACCTGC AGATACCCAA TTGTGGTTTG CCATCTGCAA 1080 ATCTGGCCGC ACCTAACCTC AGTGTGGAGG AAGGAAAGTC TATCACATTA TCCTGTAGTG 1140 TGGCAGGTGA TCCGGTTCCT AATATGTATT GGGATGTTGG TAACCTGGTT TCCAAACATA 1200 TGAATGAAAC AAGCCACACA CAGGGCTCCT TAAGGATAAC TAACATTTCA TCCGATGACA 1260 GTGGGAAGCA GATCTCTTGT GTGGCGGAAA ATCTTGTAGG AGAAGATCAA GATTCTGTCA 1320 ACCTCACTGT GCATTTTGCA CCAACTATCA CATTTCTCGA ATCTCCAACC TCAGACCACC 1380 ACTGGTGCAT TCCATTCACT GTGAAAGGCA ACCCCAAACC AGCGCTTCAG TGGTTCTATA 1440 ACGGGGCAAT ATTGAATGAG TCCAAATACA TCTGTACTAA AATACATGTT ACCAATCACA 1500 CGGAGTACCA CGGCTGCCTC CAGCTGGATA ATCCCACTCA CATGAACAAT GGGGACTACA 1560 CTCTAATAGC CAAGAATGAG TATGGGAAGG ATGAGAAACA GATTTCTGCT CACTTCATGG 1620 GCTGGCCTGG AATTGACGAT GGTGCAAACC CAAATTATCC TGATGTAATT TATGAAGATT 1680 ATGGAACTGC AGCGAATGAC ATCGGGGACA CCACGAACAG AAGTAATGAA ATCCCTTCCA 1740 CAGACGTCAC TGATAAAACC GGTCGGGAAC ATCTCTCGGT CTATGCTGTG GTGGTGATTG 1800 CGTCTGTGGT GGGATTTTGC CTTTTGGTAA TGCTGTTTCT GCTTAAGTTG GCAAGACACT 1860 CCAAGTTTGG CATGAAAGAT TTCTCATGGT TTGGATTTGG GAAAGTAAAA TCAAGACAAG 1920 GTGTTGGCCC AGCCTCCGTT ATCAGCAATG ATGATGACTC TGCCAGCCCA CTCCATCACA 1980 TCTCCAATGG GAGTAACACT CCATCTTCTT CGGAAGGTGG CCCAGATGCT GTCATTATTG 2040 GAATGACCAA GATCCCTGTC ATTGAAAATC CCCAGTACTT TGGCATCACC AACAGTCAGC 2100 TCAAGCCAGA CACATTTGTT CAGCACATCA AGCGACATAA CATTGTTCTG AAAAGGGAGC 2160 TAGGCGAAGG AGCCTTTGGA AAAGTGTTCC TAGCTGAATG CTATAACCTC TGTCCTGAGC 2220 AGGACAAGAT CTTGGTGGCA GTGAAGACCC TGAAGGATGC CAGTGACAAT GCACGCAAGG 2280 ACTTCCACCG TGAGGCCGAG CTCCTGACCA ACCTCCAGCA TGAGCACATC GTCAAGTTCT 2340 ATGGCGTCTG CGTGGAGGGC GACCCCCTCA TCATGGTCTT TGAGTACATG AAGCATGGGG 2400 ACCTCAACAA GTTCCTCAGG GCACACGGCC CTGATGCCGT GCTGATGGCT GAGGGCAACC 2460 CGCCCACGGA ACTGACGCAG TCGCAGATGC TGCATATAGC CCAGCAGATC GCCGCGGGCA 2520 TGGTCTACCT GGCGTCCCAG CACTTCGTGC ACCGCGATTT GGCCACCAGG AACTGCCTGG 2580 TCGGGGAGAA CTTGCTGGTG AAAATCGGGG ACTTTGGGAT GTCCCGGGAC GTGTACAGCA 2640 CTGACTACTA CAGGGTCGGT GGCCACACAA TGCTGCCCAT TCGCTGGATβ CCTCCAGAGA 2700 GCATCATGTA CAGGAAATTC ACGACGGAAA GCGACGTCTG GAGCCTGGGG GTCGTGTTGT 2760 GGGAGATTTT CACCTATGGC AAACAGCCCT GGTACCAGCT GTCAAACAAT GAGGTGATAG 2820 AGTGTATCAC TCAGGGCCGA GTCCTGCAGC GACCCCGCAC GTGCCCCCAG GAGGTGTATG 2880 AGCTGATGCT GGGGTGCTGG CAGCGAGAGC CCCACATGAG GAAGAACATC AAGGGCATCC 2940 ATACCCTCCT TCAGAACTTG GCCAAGGCAT CTCCGGTCTA CCTGGACATT CTAGGCTAGG 3000 GCCCTTTTCC CCAGACCGAT CCTTCCCAAC GTACTCCTCA GACGGGCTGA GAGGATGAAC 3060 ATCTTTTAAC TGCCGCTGGA GGCCACCAAG CTGCTCTCCT TCACTCTGAC AGTATTAACA 3120 TCAAAGACTC CGAGAAGCTC TCGAGGGAAG CAGTGTGTAC TTCTTCATCC ATAGACACAG 3180 TATTGACTTC TTTTTGGCAT TATCTCTTTC TCTCTTTCCA TCTCCCTTGG TTGTTCCTTT 3240 TTCTTTTTTT AAATTTTCTT TTTCTTCTTT TTTTTCGTCT TCCCTGCTTC ACGATTCTTA 3300 CCCTTTCTTT TGAATCAATC TGGCTTCTGC ATTACTATTA ACTCTGCATA GACAAAGGCC 3360 TTAACAAACG TAATTTGTTA TATCAGCAGA CACTCCAGTT TGCCCACCAC AACTAACAAT 3420 GCCTTGTTGT ATTCCTGCCT TTGATGTGGA TGAAAAAAAG GGAAAACAAA TATTTCACTT 3480 AAACTTTGTC ACTTCTGCTG TACAGATATC GAGAGTTTCT ATGGATTCAC TTCTATTTAT 3540 TTATTATTAT TACTGTTCTT ATTGTTTTTG GATGGCTTAA GCCTGTGTAT AAAAAAGAAA 3600 ACTTGTGTTC AATCTGTGAA GCCTTTATCT ATGGGAGATT AAAACCAGAG AGAAAGAAGA 3660 TTTATTATGA ACCGCAATAT GGGAGGAACA AAGACAACCA CTGGGATCAG CTGGTGTCAG 3720 TCCCTACTTA GGAAATACTC AGCAACTGTT AGCTGGGAAG AATGTATTCG GCACCTTCCC 3780 CTGAGGACCT TTCTGAGGAG TAAAAAGACT ACTGGCCTCT GTGCCATGGA TGATTCTTTT 3840 CCCATCACCA GAAATGATAG CGTGCAGTAG AGAGCAAAGA TGGCTTCCGT GAGACACAAG 3900 ATGGCGCATA GTGTGCTCGG ACACAGTTTT GTCTTCGTAG GTTGTGATGA TAGCACTGGT 3960 TTGTTTCTCA AGCGCTATCC ACAGAACCTT TGTCAACTTC AGTTGAAAAG AGGTGGATTC 4020 ATGTCCAGAG CTCATTTCGG GGTCAGGTGG GAAAGCC
Seq ID NO: 396 Protein sequence Protein Accession #: AAL67965.1
11 21 MSSWIRWHGP AMARLWGFCW LWGFWRAAF ACPTSCKCSA SRIWCSDPSP GIVAFPRLEP 60 NSVDPENITE IFIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAHKA FLKNSNLQHI 120 NFTRNKLTSL SRKHFRHLDL SELILVGNPF TCSCDIMWIK TLQEAKSSPD TQDLYCLNES 180 SKNIPLANLQ IPNCGLPSAN LAAPNLTVEE GKSITLSCSV AGDPVPNMYW DVGNLVSKHM 240 NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH 300 WCIPFTVKGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT 360 LIAKNEYGKD EKQISAHFMG WPGIDDGANP NYPDVIYEDY GTAANDIGDT TNRSNEIPST 420 DVTDKTGREH LSVYAVWIA SWGFCLLVM LFLLKLARHS KFGMKDFSWF GFGKVKSRQG 480 VGPASVISND DDSASPLHHI SNGSNTPSSS EGGPDAVIIG MTKIPVIENP QYFGITNSQL 540 KPDTFVQHIK RHNIVLKREL GEGAFGKVFL AECYNLCPEQ DKILVAVKTL KDASDNARKD 600 FHREAELLTN LQHEHIVKFY GVCVEGDPLI MVFEYMKHGD LNKFLRAHGP DAVLMAEGNP 660 PTELTQSQML HIAQQIAAGM VYLASQHFVH RDLATRNCLV GENLLVKIGD FGMSRDVYST 720 DYYRVGGHTM LPIRWMPPES IMYRKFTTES DVWSLGWLW EIFTYGKQPW YQLSNNEVIE 780 CITQGRVLQR PRTCPQEVYE LMLGCWQREP HMRKNIKGIH TLLQNLAKAS PVYLDILG
Seq ID NO: 397 DNA sequence Nucleic Acid Accession # : AB052906 Coding sequence : 74. .814
1 11 21 31 41 51 1 1 1 1 | 1 | 1 | 1 | 1 AAAACCTTGA GGTGATTCAT CTTCCAGGCT CTCCTTCCAT CAAGTCTCTC CTCCCTAGCG 60
CTCTGGGTCC TTAATGGCAG CAGCCGCCGC TACCAAGATC CTTCTGTGCC TCCCGCTTCT 120
GCTCCTGCTG TCCGGCTGGT CCCGGGCTGG GCGAGCCGAC CCTCACTCTC TTTGCTATGA 180
CATCACCGTC ATCCCTAAGT TCAGACCTGG ACCACGGTGG TGTGCGGTTC AAGGCCAGGT 240
GGATGAAAAG ACTTTTCTTC ACTATGACTG TGGCAACAAG ACAGTCACAC CTGTCAGTCC 300
CCTGGGGAAG AAACTAAATG TCACAACGGC CTGGAAAGCA CAGAACCCAG TACTGAGAGA 360
GGTGGTGGAC ATACTTACAG AGCAACTGCG TGACATTCAG CTGGAGAATT ACACACCCAA 420
GGAACCCCTC ACCCTGCAGG CCAGGATGTC TTGTGAGCAG AAAGCTGAAG GACACAGCAG 480
TGGATCTTGG CAGTTCAGTT TCGATGGGCA GATCTTCCTC CTCTTTGACT CAGAGAAGAG 540
AATGTGGACA ACGGTTCATC CTGGAGCCAG AAAGATGAAA GAAAAGTGGG AGAATGACAA 600
GGTTGTGGCC ATGTCCTTCC ATTACTTCTC AATGGGAGAC TGTATAGGAT GGCTTGAGGA 660
CTTCTTGATG GGCATGGACA GCACCCTGGA GCCAAGTGCA GGAGCACCAC TCGCCATGTC 720
CTCAGGCACA ACCCAACTCA GGGCCACAGC CACCACCCTC ATCCTTTGCT GCCTCCTCAT 780
CATCCTCCCC TGCTTCATCC TCCCTGGCAT CTGAGGAGAG TCCTTTAGAG TGACAGGTTA 840
AAGCTGATAC CAAAAGGCTC CTGTGAGCAC GGTCTTGATC AAACTCGCCC TTCTGTCTGG 900
CCAGCTGCCC ACGACCTACG GTGTATGTCC AGTGGCCTCC AGCAGATCAT GATGACATCA 960
TGGACCCAAT AGCTCATTCA CTGCCTTGAT TCCTTTTGCC AACAATTTTA CCAGCAGTTA 1020
TACCTAACAT ATTATGCAAT TTTCTCTTGG TGCTACCTGA TGGAATTCCT GCACTTAAAG 1080
TTCTGGCTGA CTAAACAAGA TATATCATTT TCTTTCTTCT CTTTTTGTTT GGAAAATCAA 1140
GTACTTCTTT GAATGATGAT CTCTTTCTTG CAAATGATAT TGTCAGTAAA ATAATCACGT 1200
TAGACTTCAG ACCTCTGGGG ATTCTTTCCG TGTCCTGAAA GAGAATTTTT AAATTATTTA 1260
ATAAGAAAAA ATTTATATTA ATGATTGTTT CCTTTAGTAA TTTATTGTTC TGTACTGATA 1320
TTTAAATAAA GAGTTCTATT TCCCAAAAAA AAAAAAAAAA AA
Seq ID NO: 398 Protein sequence
Protein Accesεion ff: BAB61048.1
1 11 21 31 41 51
M 1AAAAATKIL L1CLPLLLLLS G1WSRAGRADP H1SLCYDITVI P1KFRPGPRWC A1VQGQVDEKT 60
FLHYDCGNKT VTPVSPLGKK LNVTTAWKAQ NPVLREWDI LTEQLRDIQL ENYTPKEPLT 120
LQARMSCEQK AEGHSSGSWQ FSFDGQIFLL FDSEKRMWTT VHPGARKMKE KWENDK AM 180
SFHYFSMGDC IGWLEDFLMG MDSTLEPSAG APLAMSSGTT QLRATATTLI LCCLLIILPC 240 FILPGI
Seq ID NO : 399 DNA sequence
Nucleic Acid Accession # : NM_001898.1
Coding sequence : 57. - 482
11 21 31 41 51
GGCTCTCACC CTCCTCTCCT GCAGCTCCAG CTTTGTGCTC TGCCTCTGAG GAGACCATGG 60 CCCAGTATCT GAGTACCCTG CTGCTCCTGC TGGCCACCCT AGCTGTGGCC CTGGCCTGGA 120 GCCCCAAGGA GGAGGATAGG ATAATCCCGβ GTGGCATCTA TAACGCAGAC CTCAATGATG 180 AGTGGGTACA GCGTGCCCTT CACTTCGCCA TCAGCGAGTA TAACAAGGCC ACCAAAGATG 240 ACTACTACAG ACGTCCGCTG CGGGTACTAA GAGCCAGGCA ACAGACCGTT GGGGGGGTGA 300 ATTACTTCTT CGACGTAGAG GTGGGCCGCA CCATATGTAC CAAGTCCCAG CCCAACTTGG 360 ACACCTGTGC CTTCCATGAA CAGCCAGAAC TGCAGAAGAA ACAGTTGTGC TCTTTCGAGA 420 TCTACGAAGT TCCCTGGGAG AACAGAAGGT CCCTGGTGAA ATCCAGGTGT CAAGAATCCT 480 AGGGATCTGT GCCAGGCCAT TCGCACCAGC CACCACCCAC TCCCACCCCC TGTAGTGCTC 540 CCACCCCTGG ACTGGTGGCC CCCACCCTGC GGGAGGCCTC CCCATGTGCC TGCGCCAAGA 600 GACAGACAGA GAAGGCTGCA GGAGTCCTTT GTTGCTCAGC AGGGCGCTCT GCCCTCCCTC 660 CTTCCTTCTT GCTTCTAATA GCCCTGGTAC ATGGTACACA CCCCCCCACC TCCTGCAATT 720 AAACAGTAGC ATCGCC
Seq ID NO: 400 Protein sequence Protein Accession # : NP_001889.1
1 11 21 31 41 51
I I I I I I
MAQYLSTLLL LLATLAVALA WSPKEEDRII PGGIYNADLN DEWVQRALHF AISEYNKATK 60 DDYYRRPLRV LRARQQTVGG VNYFFDVEVG RTICTKSQPN LDTCAFHEQP ELQKKQLCSF 120 EIYEVPWENR RSLVKSRCQE S
Seq ID NO: 401 DNA sequence
Nucleic Acid Accession ft: NM_003976.2
Coding sequence: 299.961
11 21 31 41 51
I I I I 1
CTCTGAGCTT CTCTGAGCCT TGTTTGCTCA TCTGGAAAAA GGGGATTAAA CCATTTACCT 60 CATGGAGTTG TGAAAGAATA GCTGCAAAGC ACCTAACACA TAGTAAGGTT CCCAGTGCAG 120 CTACTTCTGC TGGGTTGAGT CTAGCTGTGT AGGCCCCTTG TTCCTCACCT GGAGAAACTG 180 GGGTGGCAGG CCGGTCCCCC ACAAAAGATA ACTCATCTCT TAATTTGCAA GCTGCCTCAA 240 CAGGAGGGTG GGGGAACAGC TCAACAATGG CTGATGGGCG CTCCTGGTGT TGATAGAGAT 300 GGAACTTGGA CTTGGAGGCC TCTCCACGCT GTCCCACTGC CCCTGGCCTA GGCGGCAGCC 360 TGCCCTGTGG CCCACCCTGG CCGCTCTGGC TCTGCTGAGC AGCGTCGCAG AGGCCTCCCT 420 GGGCTCCGCG CCCCGCAGCC CTGCCCCCCG CGAAGGCCCC CCGCCTGTCC TGGCGTCCCC 480 CGCCGGCCAC CTGCCGGGGβ GACGCACGGC CCGCTGGTGC AGTGGAAGAG CCCGGCGGCC 540 GCCGCCGCAG CCTTCTCGGC GCGCGCCCCC GCCGCCTGCA CCCCCATCTG CTCTTCCCCG 600 CGGGGGCCGC GCGGCGCGGG CTGGGGGCCC GGGCAGCCGC GCTCGGGCAG CGGGGGCGCG 660 GGGCTGCCGC CTGCGCTCGC AGCTGGTGCC GGTGCGCGCG CTCGGCCTGG GCCACCGCTC 720 CGACGAGCTG GTGCGTTTCC GCTTCTGCAG CGGCTCCTGC CGCCGCGCGC GCTCTCCACA 780 CGACCTCAGC CTGGCCAGCC TACTGGGCGC CGGGGCCCTG CGACCGCCCC CGGGCTCCCG 840 GCCCGTCAGC CAGCCCTGCT GCCGACCCAC GCGCTACGAA GCGGTCTCCT TCATGGACGT 900 CAACAGCACC TGGAGAACCG TGGACCGCCT CTCCGCCACC GCCTGCGGCT GCCTGGGCTG 960 AGGGCTCGCT CCAGGGCTTT GCAGACTGGA CCCTTACCGG TGGCTCTTCC TGCCTGGGAC 1020 CCTCCCGCAG AGTCCCACTA GCCAGCGGCC TCAGCCAGGG ACGAAGGCCT CAAAGCTGAG 1080 AGGCCCCTAC CGGTGGGTGA TGGATATCAT CCCCGAACAG GTGAAGGGAC AACTGACTAG 1140 CAGCCCCAGA GCCCTCACCC TGCGGATCCC AGCCTAAAAG ACACCAGAGA CCTCAGCTAT 1200 GGAGCCCTTC GGACCCACTT CTCACAGACT CTGGCACTGG CCAGGCCTCG AACCTGGGAC 1260 CCCTCCTCTG ATGAACACTA CAGTGGCTGA GGCATCAGCC CCCGCCCAGG CCCTGTAGGG 1320 ACAGCATTTG AAGGACACAT ATTGCAGTTG CTTGGTTGAA AGTGCCTGTG CTGGAACTGG 1380 CCTGTACTCA CTCATGGGAG CTGGCCCC
Seq ID NO: 402 Protein sequence Protein Accession #: NP 003967.1
1 11 21 31 41 51
I I I I I I
MELGLGGLST LSHCPWPRRQ PALWPTLAAL ALLSSVAEAS LGSAPRSPAP REGPPPVLAS 60 PAGHLPGGRT ARWCSGRARR PPPQPSRPAP PPPAPPSALP RGGRAARAGG PGSRARAAGA 120 RGCRLRSQLV PVRALGLGHR SDELVRFRFC SGSCRRARSP HDLSLASLLG AGALRPPPGS 180 RPVSQPCCRP TRYEAVSFMD VNSTWRTVDR LSATACGCLG
Seq ID NO: 403 DNA sequence Nucleic Acid Accession if: NM_057091.1 Coding sequence: 783..1445
11 21 31 41 51
I I I I I
ACTGGCCGCT GAGAGAAGAA TCGGGTGGAG CAGAGAGCAG CTGCTGCAGG GCAGACAGCC 60 GGACCCCCAA ATCTGCACGT ACCAGCAGTC AGCCGCCCCA CGCAGGGACC GGCTTACCCC 120 TCGCTCCCCG CCCTCACTCA CTTTCTCCCG CCCTCGGCCC GGCCTCCCAG CTCTCTACTT 180 CGCGTGTCTA CAAACTCAAC TCCCGGTTTC CGTGCCTCTC CACCGCTCGA GTTCTCTACT 240 CTCCATATCC GAGGGGCCCC TCCCAGCATC TACCCCCCTC CCAACCTCGG GGGACCTAGC 300 CAAGCTAGGG GGGACTGGAT CCGACGGGTG GAGCAGCCAG GTGAGCCCCG AAAGGTGGGG 360 CGGGGCAGGG GCGCTCCCAG CCCCACCCCG GGATCTGGTG ACGCTGGGGC TGGAATTTGA 420 CACCGGACGG CTGCGGCGGC GGGCAGGAGG CTGCTGAGGG ATGGAGTTGG GCCCGGCCCC 480 CAGACAAGGC CCGGGGGCTC CGCCAGCAGC AGGTCCCTCG GGCCCCAGCC CTCGCTGCCA 540 CCCGGGCCTG GAGCCCCACA CCCGAGGGTG CAGACTGGCT GCCAAGGCCA CACTTTTGGC 600 TAAAAGAGGC ACTGCCAGGT GTACAGTCCT GGGCATGCGC TGTTTGAGCT TCGGGGGAGA 660 GCCCAGCACT GGTCCCCGGA AAGGTGCCTA GAAGAACAAG GTGCAGGACC CCGTGCTGCC 720 TCAACAGGAG GGTGGGGGAA CAGCTCAACA ATGGCTGATG GGCGCTCCTG GTGTTGATAG 780 AGATGGAACT TGGACTTGGA GGCCTCTCCA CGCTGTCCCA CTGCCCCTGG CCTAGGCGGC 840 AGCCTGCCCT GTGGCCCACC CTGGCCGCTC TGGCTCTGCT GAGCAGCGTC GCAGAGGCCT 900 CCCTGGGCTC CGCGCCCCGC AGCCCTGCCC CCCGCGAAGG CCCCCCGCCT GTCCTGGCGT 960 CCCCCGCCGG CCACCTGCCG GGGGGACGCA CGGCCCGCTG GTGCAGTGGA AGAGCCCGGC 1020 GGCCGCCGCC GCAGCCTTCT CGGCCCGCGC CCCCGCCGCC TGCACCCCCA TCTGCTCTTC 1080 CCCGCGGGGG CCGCGCGGCG CGGGCTGGGG GCCCGGGCAG CCGCGCTCGG GCAGCGGGGG 1140 CGCGGGGCTG CCGCCTGCGC TCGCAGCTGG TGCCGGTGCG CGCGCTCGGC CTGGGCCACC 1200 GCTCCGACGA GCTGGTGCGT TTCCGCTTCT GCAGCGGCTC CTGCCGCCGC GCGCGCTCTC 1260 CACACGACCT CAGCCTGGCC AGCCTACTGG GCGCCGGGGC CCTGCGACCG CCCCCGGGCT 1320 CCCGGCCCGT CAGCCAGCCC TGCTGCCGAC CCACGCGCTA CGAAGCGGTC TCCTTCATGG 1380 ACGTCAACAG CACCTGGAGA ACCGTGGACC GCCTCTCCGC CACCGCCTGC GGCTGCCTGG 1440 GCTGAGGGCT CGCTCCAGGG CTTTGCAGAC TGGACCCTTA CCGGTGGCTC TTCCTGCCTG 1500 GGACCCTCCC GCAGAGTCCC ACTAGCCAGC GGCCTCAGCC AGGGACGAAG GCCTCAAAGC 1560 TGAGAGGCCC CTACCGGTGG GTGATGGATA TCATCCCCGA ACAGGTGAAG GGACAACTGA 1620 CTAGCAGCCC CAGAGCCCTC ACCCTGCGGA TCCCAGCCTA AAAGACACCA GAGACCTCAG 1680 CTATGGAGCC CTTCGGACCC ACTTCTCACA GACTCTGGCA CTGGCCAGGC CTCGAACCTG 1740 GGACCCCTCC TCTGATGAAC ACTACAGTGG CTGAGGCATC AGCCCCCGCC CAGGCCCTGT 1800 AGGGACAGCA TTTGAAGGAC ACATATTGCA GTTGCTTGGT TGAAAGTGCC TGTGCTGGAA 1860 CTGGCCTGTA CTCACTCATG GGAGCTGGCC CC
Seq ID NO: 404 Protein sequence Protein Accession if: NP 003967.1 1 11 21 31 41 51
I I I I I I
MELGLGGLST LSHCPWPRRQ PALWPTLAAL ALLSSVAEAS LGSAPRSPAP REGPPPVLAS 60 PAGHLPGGRT ARWCSGRARR PPPQPSRPAP PPPAPPSALP RGGRAARAGG PGSRARAAGA 120 RGCRLRSQLV PVRALGLGHR SDELVRFRFC SGSCRRARSP HDLSLASLLG AGALRPPPGS 180 RPVΞQPCCRP TRYEAVSFMD VNSTWRTVDR LSATACGCLG Seq ID NO : 405 DNA sequence
Nucleic Acid Accession ft : NM_057160 .1 Coding sequence: 1. .714
11 21 31 41 51
I I I I I
ATGCCCGGCC TGATCTCAGC CCGAGGACAG CCCCTCCTTG AGGTCCTTCC TCCCCAAGCC 60 CACCTGGGTG CCCTCTTTCT CCCTGAGGCT CCACTTGGTC TCTCCGCGCA GCCTGCCCTG 120 TGGCCCACCC TGGCCGCTCT GGCTCTGCTG AGCAGCGTCG CAGAGGCCTC CCTGGGCTCC 180 GCGCCCCGCA GCCCTGCCCC CCGCGAAGGC CCCCCGCCTG TCCTGGCGTC CCCCGCCGGC 240 CACCTGCCGG GGGGACGCAC GGCCCGCTGG TGCAGTGGAA GAGCCCGGCG GCCGCCGCCG 300 CAGCCTTCTC GGCCCGCGCC CCCGCCGCCT GCACCCCCAT CTGCTCTTCC CCGCGGGGGC 360 CGCGCGGCGC GGGCTGGGGG CCCGGGCAGC CGCGCTCGGG CAGCGGGGGC GCGGGGCTGC 420 CGCCTGCGCT CGCAGCTGGT GCCGGTGCGC GCGCTCGGCC TGGGCCACCG CTCCGACGAG 480 CTGGTGCGTT TCCGCTTCTG CAGCGGCTCC TGCCGCCGCG CGCGCTCTCC ACACGACCTC 540 AGCCTGGCCA GCCTACTGGG CGCCGGGGCC CTGCGACCGC CCCCGGGCTC CCGGCCCGTC 600 AGCCAGCCCT GCTGCCGACC CACGCGCTAC GAAGCGGTCT CCTTCATGGA CGTCAACAGC 660 ACCTGGAGAA CCGTGGACCG CCTCTCCGCC ACCGCCTGCG GCTGCCTGGG CTGAGGGCTC 720 GCTCCAGGGC TTTGCAGACT GGACCCTTAC CGGTGGCTCT TCCTGCCTGG GACCCTCCCG 780 CAGAGTCCCA CTAGCCAGCβ GCCTCAGCCA GGGACGAAGG CCTCAAAGCT GAGAGGCCCC 840 TACCGGTGGG TGATGGATAT CATCCCCGAA CAGGTGAAGG GACAACTGAC TAGCAGCCCC 900 AGAGCCCTCA CCCTGCGGAT CCCAGCCTAA AAGACACCAG AGACCTCAGC TATGGAGCCC 960 TTCGGACCCA CTTCTCACAG ACTCTGGCAC TGGCCAGGCC TCGAACCTGG GACCCCTCCT 1020 CTGATGAACA CTACAGTGGC TGAGGCATCA GCCCCCGCCC AGGCCCTGTA GGGACAGCAT 1080 TTGAAGGACA CATATTGCAG TTGCTTGGTT GAAAGTGCCT GTGCTGGAAC TGGCCTGTAC 1140 TCACTCATGG GAGCTGGCCC C
Seq ID NO: 406 Protein sequence Protein Accession ft: NP_476501.1
1 11 21 31 41 51
I I I I I I
MPGLISARGQ PLLEVLPPQA HLGALFLPEA PLGLSAQPAL WPTLAALALL SSVAEASLGS 60 APRSPAPREG PPPVLASPAG HLPGGRTARW CSGRARRPPP QPSRPAPPPP APPSALPRGG 120 RAARAGGPGS RARAAGARGC RLRSQLVPVR ALGLGHRSDE LVRFRFCSGS CRRARSPHDL 180 SLASLLGAGA LRPPPGSRPV SQPCCRPTRY EAVSFMDVNS TWRTVDRLSA TACGCLG
Seq ID NO: 407 DNA sequence
Nucleic Acid Accession ft: NM_057090.1
Coding sequence: 29..715
11 21 31 41 51
I I I I I
CTGATGGGCG CTCCTGGTGT TGATAGAGAT GGAACTTGGA CTTGGAGGCC TCTCCACGCT 60 GTCCCACTGC CCCTGGCCTA GGCGGCAGGC TCCACTTGGT CTCTCCGCGC AGCCTGCCCT 120 GTGGCCCACC CTGGCCGCTC TGGCTCTGCT GAGCAGCGTC GCAGAGGCCT CCCTGGGCTC 180 CGCGCCCCGC AGCCCTGCCC CCCGCGAAGG CCCCCCGCCT GTCCTGGCGT CCCCCGCCGG 240 CCACCTGCCG GGGGGACGCA CGGCCCGCTG GTGCAGTGGA AGAGCCCGGC GGCCGCCGCC 300 GCAGCCTTCT CGGCCCGCGC CCCCGCCGCC TGCACCCCCA TCTGCTCTTC CCCGCGGGGG 360 CCGCGCGGCG CGGGCTGGGG GCCCGGGCAG CCGCGCTCGG GCAGCGGGGG CGCGGGGCTG 420 CCGCCTGCGC TCGCAGCTGG TGCCGGTGCG CGCGCTCGGC CTGGGCCACC GCTCCGACGA 480 GCTGGTGCGT TTCCGCTTCT GCAGCGGCTC CTGCCGCCGC GCGCGCTCTC CACACGACCT 540 CAGCCTGGCC AGCCTACTGG GCGCCGGGGC CCTGCGACCG CCCCCGGGCT CCCGGCCCGT 600 CAGCCAGCCC TGCTGCCGAC CCACGCGCTA CGAAGCGGTC TCCTTCATGG ACGTCAACAG 660 CACCTGGAGA ACCGTGGACC GCCTCTCCGC CACCGCCTGC GGCTGCCTGG GCTGAGGGCT 720 CGCTCCAGGG CTTTGCAGAC TGGACCCTTA CCGGTGGCTC TTCCTGCCTG GGACCCTCCC 780 GCAGAGTCCC ACTAGCCAGC GGCCTCAGCC AGGGACGAAG GCCTCAAAGC TGAGAGGCCC 840 CTACCGGTGG GTGATGGATA TCATCCCCGA ACAGGTGAAG GGACAACTGA CTAGCAGCCC 900 CAGAGCCCTC ACCCTGCGGA TCCCAGCCTA AAAGACACCA GAGACCTCAG CTATGGAGCC 960 CTTCGGACCC ACTTCTCACA GACTCTGGCA CTGGCCAGGC CTCGAACCTG GGACCCCTCC 1020 TCTGATGAAC ACTACAGTGG CTGAGGCATC AGCCCCCGCC CAGGCCCTGT AGGGACAGCA 1080 TTTGAAGGAC ACATATTGCA GTTGCTTGGT TGAAAGTGCC TGTGCTGGAA CTGGCCTGTA 1140 CTCACTCATG GGAGCTGGCC CC
Seq ID NO: 408 Protein sequence Protein Accession if: NP 476431.1
11 21 31 41 51
MELGLGGLST LSHCPWPRRQ APLGLSAQPA LWPTLAALAL LSSVAEASLG SAPRSPAPRE 60
GPPPVLASPA GHLPGGRTAR WCSGRARRPP PQPSRPAPPP PAPPSALPRG GRAARAGGPG 120
SRARAAGARG CRLRSQLVPV RALGLGHRSD ELVRFRFCSG SCRRARSPHD LSLASLLGAG 180 ALRPPPGSRP VSQPCCRPTR YEAVSFMDVN STWRTVDRLS ATACGCLβ Seq ID NO: 409 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..1746
11 21 31 41 51
ATGCCACTGA AGCATTATCT CCTTTTGCTG GTGGGCTGCC AAGCCTGGGG TGCAGGGTTG 60 GCCTACCATG GCTGCCCTAG CGAGTGTACC TGCTCCAGGG CCTCCCAGGT GGAGTGCACC 120 GGGGCACGCA TTGTGGCGGT GCCCACCCCT CTGCCCTGGA ACGCCATGAG CCTGCAGATC 180 CTCAACACGC ACATCACTGA ACTCAATGAG TCCCCGTTCC TCAATATCTC AGCCCTCATC 240 GCCCTGAGGA TTGAGAAGAA TGAGCTGTCG CGCATCACGC CTGGGGCCTT CCGAAACCTG 300 GGCTCGCTGC GCTATCTCAG CCTCGCCAAC AACAAGCTGC AGGTTCTGCC CATCGGCCTC 360 TTCCAGGGCC TGGACAGCCT TGAGTCTCTC CTTCTGTCCA GTAACCAGCT GTTGCAGATC 420 CAGCCGGCCC ACTTCTCCCA GTGCAGCAAC CTCAAGGAGC TGCAGTTGCA CGGCAACCAC 480 CTGGAATACA TCCCTGACGG AGCCTTCGAC CACCTGGTAG GACTCACGAA GCTCAATCTG 540 GGCAAGAATA GCCTCACCCA CATCTCACCC AGGGTCTTCC AGCACCTGGG CAATCTCCAG 600 GTCCTCCGGC TGTATGAGAA CAGGCTCACG GATATCCCCA TGGGCACTTT TGATGGGCTT 660 GTTAACCTGC AGGAACTGGC TCTACAGCAG AACCAGATTG GACTGCTCTC CCCTGGTCTC 720 TTCCACAACA ACCACAACCT CCAGAGACTC TACCTGTCCA ACAACCACAT CTCCCAGCTG 780 CCACCCAGCA TCTTCATGCA GCTGCCCCAG CTCAACCGTC TTACTCTCTT TGGGAATTCC 840 CTGAAGGAGC TCTCTCTGGG GATCTTCGGG CCCATGCCCA ACCTGCGGGA GCTTTGGCTC 900 TATGACAACC ACATCTCTTC TCTACCCGAC AATGTCTTCA GCAACCTCCG CCAGTTGCAG 960 GTCCTGATTC TTAGCCGCAA TCAGATCAGC TTCATCTCCC CGGGTGCCTT CAACGGGCTA 1020 ACGGAGCTTC GGGAGCTGTC CCTCCACACC AACGCACTGC AGGACCTGGA CGGGAATGTC 1080 TTCCGCATGT TGGCCAACCT GCAGAACATC TCCCTGCAGA ACAATCGCCT CAGACAGCTC 1140 CCAGGGAATA TCTTCGCCAA CGTCAATGGC CTCATGGCCA TCCAGCTGCA GAAGAACCAG 1200 CTGGAGAACT TGCCCCTCGG CATCTTCGAT CACCTGGGGA AACTGTGTGA GCTGCGGCTG 1260 TATGACAATC CCTGGAGGTG TGACTCAGAC ATCCTTCCGC TCCGCAACTG GCTCCTGCTC 1320 AACCAGCCTA GGTTAGGGAC GGACACTGTA CCTGTGTGTT TCAGCCCAGC CAATGTCCGA 1380 GGCCAGTCCC TCATTATCAT CAATGTCAAC GTTGCTGTTC CAAGCGTCCA TGTCCCTGAG 1440 GTGCCTAGTT ACCCAGAAAC ACCATGGTAC CCAGACACAC CCAGTTACCC TGACACCACA 1500 TCCGTCTCTT CTACCACTGA GCTAACCAGC CCTGTGGAAG ACTACACTGA TCTGACTACC 1560 ATTCAGGTCA CTGATGACCβ CAGCGTTTGG GGCATGACCC AGGCCCAGAG CGGGCTGGCC 1620 ATTGCCGCCA TTGTAATTGG CATTGTCGCC CTGGCCTGCT CCCTGGCTGC CTGCGTCGGC 1680 TGTTGCTGCT GCAAGAAGAG GAGCCAAGCT GTCCTGATGC AGATGAAGGC ACCCAATGAG 1740 TGTTAAAGAG GCAGGCTGGA GCAGGGCTGG GGAATGATGG GACTGGAGGA CCTGGGAATT 1800 TCATCTTTCT GCCTCCACCC CTGGGTCCAT GGAGCTTTCC CGTGATTGCT CTTTCTGGCC 1860 CTAGATAAAG GTGTGCCTAC CTCTTCCTGA CTTGCCTGAT TCTCCCGTAG AGAAGCAGGT 1920 CGTGCCGGAC CTTCCTACAA TCAGGAAGAT AGATCCAACT GGCCATGGCA AAAGCCCTGG 1980 GGATTTCCGA TTCATACCCC TGGGCTTCCT TCGAGAGGGC TCTTCCTCCA AATCCTCCCC 2040 ACCTGTCCTC CAAGAACAGC CTTCCCTGCG CCCAGGCCCC CTCCGGGCCT CTGTAGACTC 2100 AGTTAGTCCA CAGCCTGCTC ACTTCGTGGG AATAGTTCTC CGCTGAGATA GCCCCTCTCG 2160 CCTAAGTATT ATGTAAGTTG ATTTCCCTTC TTTTGTTTCT CTTGTTTGTG CTATGGCTTG 2220 ACCCAGCATG TCCCCTCAAA TGAAAGTTCT CCCCTTGATT TTCTGCTCCT GAAGGCAGGG 2280 TGAGTTCTCT CCTCAAAGAA GACTTCAAAC CATTTAACTG GTTTCTTAAG AGCCGTCAAT 2340 CAGCCTGGTT TTGGGGATGC TATGAAAGAG AGAAGGAAAA TCATGCCGCT CAGTTCCTGG 2400 AGACAGAAGA GCCGTCATCA GTGTCTCACT TGTGATTTTT ATCTGGAAAA GGAAGAAACA 2460 CCCCAGCACA GCAAGCTCAG CCTTTTAGAG AAGGATATTT CCAAACTGCA AACTTTGCTT 2520 TGAAAAGTTT AGCCCTTTAA GGAATGAAAT CATGTAGAAT TTTGGACTTC TAAAAACATT 2580 AAAATCAGCT TATTAATACG GGATAGAGAA AGAAATCTGG TGCCTGGGGG TCCCTGTGTT 2640 CACCCCTAGA GTTTGTTTTA AAATTTTTAA TTGAAGCATG TGAAGTGTAC STGCAGAAAA 2700 GTGGGAACAT GATAGTGTAT GGCTTGGTGG ATTTTCACAA ACTGAACATA CCTGTGTAAT 2760 CAGCATCTAG ACCCAGACCC AGAGCATCAC AAATATCCCC CATCCTGGGC TTTTCCCAGA 2820 GGAGATGGGG GCTTCTGAAG ATGGACTTAC CTGGGACCTG CCCCCCATGA GCCAGGACGG 2880 TCCCCCCACA GTCAGCCTGT GCAAAGGCCC CGTGGCCAGG GGTGGAGGAG AATATGTGGG 2940 TGTGGACAGG ATGGGAGACT GTGGCCTGAA CAGGAGATTT TATTATATCT GGAGACCCTG 3000 AGAGACCCTG AGACCTGGGG CACCATGGCT GGCCAGGTCA GAAGCATCCT GACTGCAGAG 3060 GTCCGTGCAG CCACACCCTC TTCCCTGCCA GCAAGTTGTC TGCGGCTCAT CGGAGGCCCC 3120 TCCGCCTGGA GCCTTCTATG GACGTGATAT GCCTGTATCT GTTTTTAATT TTCATTCTTC 3180 ACTTAGGGGA AGTGAAATCG CTCAGAGATG AGATCCTTTA ATTGAAAACG AAGTGTAACG 3240 GAATCTAGTG TCTTTCTAAT GTGGTAAAAT TCTCCATCAA CATCACAGTC AGCTGGCAGC 3300 TGAACTTCAG AATCTCACTT ACAGCAGGCG ACACGGGGGT ACACCGATGG GTCACACTGG 3360 GTCTGGGGGC TCCCTGGAGC TCCTCCTGCG TGTGGTCTGG TTAGGAGTTG AGTTGTTTGC 3420 TCCAGGGTTA TTCTCCTCCT CGAGTCACAG TCACACGAAT ACCTGCCTTC TCTGGCTTTC 3480 CTGCTATACA CATATTCACA TGGCGCTCAA GAAGTTAGGC TCATGGCAAC GTGTGTCTTT 3540 CTCTGGACAA CTGGCCCAGT TTACAGTGAA ATGGAGAATT TCAGGTCTCC ACGTCTGCCC 3600 AGGAAAGAAC TTCAGCTGAC TCCACGGGGA TCTGGAAATC CACGACCAAT CCCGATCGGC 3660 TCTTATTAGC TCCCCGCTCC ACAAGACACC TGTGCTTTGG AAATCCACCA CCAATCCCGA 3720 TCGGCTCTTA TTAGCTCCCC GCTCCACAAG ACACCTGTGA TCTGGAAATC TACCACCAAT 3780 CCCGATCGGC TCTTATTAGC TCCCCGCTCC ACAAGACACC TGTGACATCC TCCAGGGCCA 3840 CAGGAGCACG TGCTGACCAG TTTTCCCTTC CAGTTCCTGC ACAAAAAGTG TCCAGAGGGC 3900 TGTTTGCAAA CACTAGTGCA CTTTGTAGCT TTTCACCCTC TGTCCCAGGG AATCTAGGAG 3960 AGATGAGGCC CGTCAGAGTC AAGAGATGTC ATCCCCCCAG GGTCTCCAAG GCATTTCCAC 4020 ACTATTGGTG GCACCTGGAG GACATGCACC AAGGCTTGCC AGAGCCAACA GGAAGTGAGC 4080 CCAGAGCATG GCACATGAGC ATCACCCGCT GATGGTGGCC TGCTGTGCCT GGTGCCAACA 4140 GGGGCATCCC GGCCCGTACC CCTCCAGACA GGAAGCATGG GTTTGCCCAC AGACCTGTCG 4200 GGTGCTCCTG TGAGTGGCCT CCAGATGTCT TTGTGCATAG GCACAAGTGG GCCAGGGCTG 4260 GAGGGAGGTG GGAAACCTCA TCATCCGGTG GGCCCTGCCA ATCTTAACCC AGAACCCTTA 4320 GGTATTCCTG GCAGTAGCCA TGACATTGGA GCACCTTCCT CTCCAGCCAG AGGCTGACCT 4380 GAGGGCCACT GTCCTCAGAT GACACCACCC AGGAGCACCC TAGGTGAGGG GTGAGGGCCC 4440 CCTTATGTGA ACCTCTTGCC TCTTCCTTTC TCCCATCAGA GTGGTTGGAT GGAGCCATTG 4500 GCCTCCTTTT CTTCAGCGGG CCCTTCAACC TCTCTGCACC ATGTTGTCTG GCTGAGGAGC 4560 TACTAGAAAA GCTGAGTGGA GTCTCCTTTC CAACAGGATG ATGCATTTGC TCAATTCTCA 4620 GGGCTGGAAT GAGCCGGCTG GTCCCCCAGA AAGCTGGAGT GGGGTACAGA GTTCAGTTTT 4680 CCTCTCTGTT TACAGCTCCT TGACAGTCCC ACGCCCATCT GGAGTGGGAG CTGGGAGTTA 4740 GTGTTGGAGA AGAAACAACA AAAGCCAATT AGAACCACTA TTTTTAAAAA GTGCTTACTG 4800 TGCACAGATA CTCTTCAAGC ACTGGACGTG GATTCTCTCT CTAGCCCTCA GCACCCCTGC 4860 GGTAGGAGTG CCGCCTCTAC CCACTTGTGA TGGGGTACAG AGGCACTTGC TCTTCTGCAT 4920 GGTGTTCAAT AGGCTGGGAG TTTTATTTAT CTCTTCAAAC TTTGTACAAG AGCTCATGGC 4980 TTGTCTTGGG CTTTCGTCAT TAAACCAAAG GAAATGGAAG CCATTCCCCT GTTGCTCTCC 5040 TTAGTCTTGG TCATCAGAAC CTCACTTGGT ACCATATAGA TCAAAAGCTT TGTAACCACA 5100 GGAAAAAATA AACTCTTCCA TCCCTTAAAG AATAGAATAG TTTGTCCCTC TCATGGGAAT 5160 TGGGCTGTAT GTATATTGTT CTTCCTCCTT AGAATTTAGA GATACAAGAG TTCTACTTAG 5220 AACTTTTCAT GGACACAATT TCCACAACCT TTCAGATGCT GATGTAGAGC TATTGGGAAA 5280 GAACTTCCAA ACTCAGGAAG TTTGCAGAGA GCAGACAGCT AGAGATAACT CGGGACCCAG 5340 AGTTGGTCGA CAGATGTTAG ATGTATCCTA GCTTTTAGCC ATAAACCACT CAAAGATTCA 5400 GCCCCCAGAT CCCACAGTCA GAACTGAATC TGCGTTGTTG GGAAGCCAGC AGTGGCCTTG 5460 GGAAGGAAGC CATGGCTGTβ GTTCAGAGAG GGTGGGCTGG CAAGCCACTT CCGGGGAAAA 5520 CTCCTTCCGC CCCAGGTTTC TTCTTCTCTT AAGGAGAGAT TGTTCTCACC AACCCGCTGC 5580 CTTCATGCTG CCTTCAAAGC TAGATCATGT TTGCCTTGCT TAGAGAATTA CTGCAAATCA 5640 GCCCCAGTGC TTGGCGATGC ATTTACAGAT TTCTAGGCCC TCAGGGTTTT GTAGAGTGTG 5700 AGCCCTGGTG GGCAGGGTTG GGGGGTCTGT CTTCTGCTGβ ATGCTGCTTG TAATCCATTT 5760 GGTGTACAGA ATCAACAATA AATAATATAC ATGTAT
Seq ID NO: 410 Protein sequence Protein Accession ft: BAB84587.1
11 21 31 41 51
I I I I I
MPLKHYLLLL VGCQAWGAGL AYHGCPSECT CSRASQVECT GARIVAVPTP LPWNAMSLQI 60 LNTHITELNE SPFLNISALI ALRIEKNELS RITPGAFRNL GSLRYLSLAN NKLQVLPIGL 120 FQGLDSLESL LLSSNQLLQI QPAHFSQCSN LKELQLHGNH LEYIPDGAFD HLVGLTKLNL 180 GKNSLTHISP RVFQHLGNLQ VLRLYENRLT DIPMGTFDGL VNLQELALQQ NQIGLLSPGL 240 FHNNHNLQRL YLSNNHISQL PPSIFMQLPQ LNRLTLFGNS LKELSLGIFG PMPNLRELWL 300 YDNHISSLPD NVFSNLRQLQ VLILSRNQIS FISPGAFNGL TELRELSLHT NALQDLDGNV 360 FRMLANLQNI SLQNNRLRQL PGNIFANVNG LMAIQLQNNQ LENLPLGIFD HLGKLCELRL 420 YDNPWRCDSD ILPLRNWLLL NQPRLGTDTV PVCFSPANVR GQSLIIINVN VAVPSVHVPE 480 VPSYPETPWY PDTPSYPDTT SVSSTTELTS PVEDYTDLTT IQVTDDRSVW GMTQAQSGLA 540 IAAIVIGIVA LACSLAACVG CCCCKKRSQA VLMQMKAPNE C
Seq ID NO: 411 DNA sequence Nucleic Acid Accession #: XM_098151 Coding sequence : 1.. 47
1 11 21 31 41 51 1 1 11 11 1 1 | 1 | 1
ATGATGCATT TGCTCAATTC TCAGGGCTGG AATGAGCCGG CTGGTCCCCC AGAAAGCTGG 60
AGTGGGGTAC AGAGTTCAGT TTTCCTCTCT GTTTACAGCT CCTTGACAGT CCCACGCCCA 120
TCTGGAGTGG GAGCTGGGAG TCAGTGTTGG AGAAGAAACA ACAAAAGCCA ATTAGAACCA 180
CTATTTTTAA AAAGTGCTTA CTGTGCACAG ATACTCTTCA AGCACTGGAC GTGGATTCTC 240
TCTCTAGCCC TCAGCACCCC TGCGGTAGGA GTGCCGCCTC TACCCACTTG TGATGGGGTA 300
CAGAGGCACT TGCTCTTCTG CATGGTGTTC AATAGGCTGG GAGTTTTATT TATCTCTTCA 360
AACTTTGTAC AAGAGCTCAT GGCTTGTCTT GGGCTTTCGT CATTAAACCA AAGGAAATGG 420
AAGCCATTCC CCTGTTGCTC TCCTTAG
Seq ID NO: 412 Protein sequence
Protein Accession ft: XP 098151
11 21 31 41 51 I
MMHLLNSQGW NEPAGPPESW SGVQSSVFLS VYSSLTVPRP SGVGAGSQCW RRNNKSQLEP 60 LFLKSAYCAQ ILFKHWTWIL SLALSTPAVG VPPLPTCDGV QRHLLFCMVF NRLGVLFISS 120 NFVQELMACL GLSSLNQRKW KPFPCCSP
Seq ID NO: 413 DNA sequence
Nucleic Acid Accesεion ff: NM_002658.1
Coding sequence: 77..1372
60
Figure imgf001117_0001
120
GAGCGACTCC AAAGGCAGCA ATGAACTTCA TCAAGTTCCA TCGAACTGTG ACTGTCTAAA 180
TGGAGGAACA TGTGTGTCCA ACAAGTACTT CTCCAACATT CACTGGTGCA ACTGCCCAAA 240
GAAATTCGGA GGGCAGCACT GTGAAATAGA TAAGTCAAAA ACCTGCTATG AGGGGAATGG 300
TCACTTTTAC CGAGGAAAGG CCAGCACTGA CACCATGGGC CGGCCCTGCC TGCCCTGGAA 360
CTCTGCCACT GTCCTTCAGC AAACGTACCA TGCCCACAGA TCTGATGCTC TTCAGCTGGG 420
CCTGGGGAAA CATAATTACT GCAGGAACCC AGACAACCGG AGGCGACCCT GGTGCTATGT 480
GCAGGTGGGC CTAAAGCCGC TTGTCCAAGA GTGCATGGTG CATGACTGCG CAGATGGAAA 540
AAAGCCCTCC TCTCCTCCAG AAGAATTAAA ATTTCAGTGT GGCCAAAAGA CTCTGAGGCC 600
CCGCTTTAAG ATTATTGGGG GAGAATTCAC CACCATCGAG AACCAGCCCT GGTTTGCGGC 660
CATCTACAGG AGGCACCGGG GGGGCTCTGT CACCTACGTG TGTGGAGGCA GCCTCATCAG 720
CCCTTGCTGG GTGATCAGCG CCACACACTG CTTCATTGAT TACCCAAAGA AGGAGGACTA 780
CATCGTCTAC CTGGGTCGCT CAAGGCTTAA CTCCAACACG CAAGGGGAGA TGAAGTTTGA 840
GGTGGAAAAC CTCATCCTAC ACAAGGACTA CAGCGCTGAC ACGCTTGCTC ACCACAACGA 900
CATTGCCTTG CTGAAGATCC GTTCCAAGGA GGGCAGGTGT GCβCAGCCAT CCCGGACTAT 960
ACAGACCATC TGCCTGCCCT CGATGTATAA CGATCCCCAG TTTGGCACAA GCTGTGAGAT 1020
CACTGGCTTT GGAAAAGAGA ATTCTACCGA CTATCTCTAT CCGGAGCAGC TGAAAATGAC 1080 TGTTGTGAAG CTGATTTCCC ACCGGGAGTG TCAGCAGCCC CACTACTACG GCTCTGAAGT 1140 CACCACCAAA ATGCTATGTG CTGCTGACCC CCAATGGAAA ACAGATTCCT GCCAGGGAGA 1200 CTCAGGGGGA CCCCTCGTCT GTTCCCTCCA AGGCCGCATG ACTTTGACTG GAATTGTGAG 1260 CTGGGGCCGT GGATGTGCCC TGAAGGACAA GCCAGGCGTC TACACGAGAG TCTCACACTT 1320 CTTACCCTGG ATCCGCAGTC ACACCAAGGA AGAGAATGGC CTGGCCCTCT GAGGGTCCCC 1380 AGGGAGGAAA CGGGCACCAC CCGCTTTCTT GCTGGTTGTC ATTTTTGCAG TAGAGTCATC 1440 TCCATCAGCT GTAAGAAGAG ACTGGGAAGA TAGGCTCTGC ACAGATGGAT TTGCCTGTGG 1500 CACCACCAGG GTGAACGACA ATAGCTTTAC CCTCACGGAT AGGCCTGGGT GCTGGCTGCC 1560 CAGACCCTCT GGCCAGGATG GAGGGGTGGT CCTGACTCAA CATGTTACTG ACCAGCAACT 1620 TGTCTTTTTC TGGACTGAAG CCTGCAGGAG TTAAAAAGGG CAGGGCATCT CCTGTGCATG 1680 GGCTCGAAGG GAGAGCCAGC TCCCCCGACC GGTGGGCATT TGTGAGGCCC ATGGTTGAGA 1740 AATGAATAAT TTCCCAATTA GGAAGTGTAA GCAGCTGAGG TCTCTTGAGG GAGCTTAGCC 1800 AATGTGGGAG CAGCGGTTTG GGGAGCAGAG ACACTAACGA CTTCAGGGCA GGGCTCTGAT 1860 ATTCCATGAA TGTATCAGGA AATATATATG TGTGTGTATG TTTGCACACT TGTTGTGTGG 1920 GCTGTGAGTG TAAGTGTGAG TAAGAGCTGG TGTCTGATTG TTAAGTCTAA ATATTTCCTT 1980 AAACTGTGTG GACTGTGATG CCACACAGAG TGGTCTTTCT GGAGAGGTTA TAGGTCACTC 2040 CTGGGGCCTC TTGGGTCCCC CACGTGACAG TGCCTGGGAA TGTACTTATT CTGCAGCATG 2100 ACCTGTGACC AGCACTGTCT CAGTTTCACT TTCACATAGA TGTCCCTTTC TTGGCCAGTT 2160 ATCCCTTCCT TTTAGCCTAG TTCATCCAAT CCTCACTGGG TGGGGTGAGG ACCACTCCTT 2220 ACACTGAATA TTTATATTTC ACTATTTTTA TTTATATTTT TGTAATTTTA AATAAAAGTG 2280 ATCAATAAAA TGTGATTTTT CTGA
Seq ID NO: 414 Protein sequence Protein Accesεion ft: NP 002649.1
11 21 31 41 51
I I I I I
MRALLARLLL CVLWSDSKG SNELHQVPSN CDCLNGGTCV SNKYFSNIHW CNCPKKFGGQ 60 HCEIDKSKTC YEGNGHFYRG KASTDTMGRP CLPWNSATVL QQTYHAHRSD ALQLGLGKHN 120 YCRNPDNRRR PWCYVQVGLK PLVQECMVHD CADGKKPSSP PEELKFQCGQ KTLRPRFKII 180 GGEFTTIENQ PWFAAIYRRH RGGSVTYVCG GSLISPCWVI SATHCFIDYP KKEDYIVYLG 240 RSRLNSNTQG EMKFEVENLI LHKDYSADTL AHHNDIALLK IRSKEGRCAQ PSRTIQTICL 300 PSMYNDPQFG TSCEITGFGK ENSTDYLYPE QLKMTWKLI SHRECQQPHY YGSEVTTKML 360 CAADPQWKTD SCQGDSGGPL VCSLQGRMTL TGIVSWGRGC ALKDKPGVYT RVSHFLPWIR 420 SHTKEENGLA L
Seq ID NO: 415 DNA εequence
Nucleic Acid Accession #: NM_024422.1
Coding sequence: 202..2907
11 21 31 41 51
I I I I I
CGCCAAAGGA AAAGCCCCTT GGATGAGAGG CAGGCGCTTC AGAGAAGCTA AGAAAAGCAC 60
CTCTCCGCGC GCCCCACCTC CTCCGCCTCG CGCTCCTCCT GAGCAGCGGG CCCAGACTGC 120
GCTCCGGCCG CGGCCCTCGC CCCGCGGAGC CCTCCTACCC CGGCCCGACG CTCGGCCCGC 180
GACCTGCCCC GAGCCCTCTC CATGGAGGCA GCCCGCCCCT CCGGCTCCTG GAACGGAGCC 240
CTCTGCCGGC TGCTCCTGCT GACCCTCGCG ATCTTAATAT TTGCCAGTGA TGCCTGCAAA 300
AATGTGACAT TACATGTTCC CTCCAAACTA GATGCCGAGA AACTTGTTGG TAGAGTTAAC 360
CTGAAAGAGT GCTTTACAGC TGCAAATCTA ATTCATTCAA GTGATCCTGA CTTCCAAATT 420
TTGGAGGATG GTTCAGTCTA TACAACAAAT ACTATTCTAT TGTCCTCGGA GAAGAGAAGT 480
TTTACCATAT TACTTTCCAA CACTGAGAAC CAAGAAAAGA AGAAAATATT TGTCTTTTTG 540
GAGCATCAAA CAAAGGTCCT AAAGAAAAGA CATACTAAAG AAAAAGTTCT AAGGCGCGCC 600
AAGAGAAGAT GGGCTCCAAT TCCTTGTTCG ATGCTAGAAA ACTCCTTGGG TCCTTTTCCA 660
CTTTTCCTTC AACAGGTTCA ATCTGACACG GCCCAAAACT ATACCATATA CTATTCCATA 720
AGAGGTCCTG GAGTTGACCA AGAACCTCGG AATTTATTTT ATGTGGAGAG AGACACTGGA 780
AACTTGTATT GTACTCGTCC TGTAGATCGT GAGCAGTATG AATCTTTTGA GATAATTGCC 840
TTTGCAACAA CTCCAGATGG GTATACTCCA GAACTTCCAC TGCCCCTAAT AATCAAAATA 900
GAGGATGAAA ATGATAACTA CCCAATTTTT ACAGAAGAAA CTTATACTTT TACAATTTTT 960
GAAAATTGCA GAGTGGGCAC TACTGTGGGA CAAGTGTGTG CTACTGACAA AGATGAGCCT 1020
GACACGATGC ACACACGCCT GAAGTACTCC ATCATTGGGC AGGTGCCACC ATCACCCACC 1080
CTATTTTCTA TGCATCCAAC TACAGGCGTG ATCACCACAA CATCATCTCA GCTAGACAGA 1140
GAGTTAATTG ACAAGTACCA GTTGAAAATA AAAGTACAAG ACATGGATGG TCAGTATTTT 1200
GGTCTACAGA CAACTTCAAC TTGTATCATT AACATTGATG ATGTAAATGA CCACTTGCCA 1260
ACATTTACTC GTACTTCTTA TGTGACATCA GTGGAAGAAA ATACAGTTGA TCTGGAAATC 1320
TTACGAGTTA CTGTTGAGGA TAAGGACTTA GTGAATACTG CTAACTGGAG AGCTAATTAT 1380
ACCATTTTAA AGGGCAATGA AAATGGCAAT TTTAAAATTG TAACAGATGC CAAAACCAAT 1440
GAAGGAGTTC TTTGTGTAGT TAAGCCTTTG AATTATGAAG AAAAGCAACA GATGATCTTG 1500
CAAATTGGTG TAGTTAATGA AGCTCCATTT TCCAGAGAGG CTAGTCCAAG ATCAGCCATG 1560
AGCACAGCAA CAGTTACTGT TAATGTAGAA GATCAGGATG AGGGCCCTGA GTGTAACCCT 1620
CCAATACAGA CTGTTCGCAT GAAAGAAAAT GCAGAAGTGG GAACAACAAG CAATGGATAT 1680
AAAGCATATG ACCCAGAAAC AAGAAGTAGC AGTGGCATAA GGTATAAGAA ATTAACTGAT 1740
CCAACAGGGT GGGTCACCAT TGATGAAAAT ACAGGATCAA TCAAAGTTTT CAGAAGCCTG 1800
GATAGAGAGG CAGAGACCAT CAAAAATGGC ATATATAATA TTACAGTCCT TGCATCAGAC 1860
CAAGGAGGGA GAACATGTAC GGGGACACTG GGCATTATAC TTCAAGACGT GAATGATAAC 1920
AGCCCATTCA TACCTAAAAA GACAGTGATC ATCTGCAAAC CCACCATGTC ATCTGCGGAG 1980
ATTGTTGCGG TTGATCCTGA TGAGCCTATC CATGGCCCAC CCTTTGACTT TAGTCTGGAG 2040
AGTTCTACTT CAGAAGTACA GAGAATGTGG AGACTGAAAG CAATTAATGA TACAGCAGCA 2100
CGTCTTTCCT ATCAGAATGA TCCTGCATTT GGCTCATATG TAGTACCTAT AACAGTGAGA 2160
GATAGACTTG GCATGTCTAG TGTCACTTCA TTGGATGTTA CACTGTGTGA CTGCATTACC 2220
GAAAATGACT GCACACATCG TGTAGATCCA AGGATTGGCG GTGGAGGAGT ACAACTTGGA 2280
AAGTGGGCCA TCCTTGCAAT ATTGTTGGGC ATAGCATTGC TCTTTTGCAT CCTGTTTACG 2340
CTGGTCTGTG GGGCTTCTGG GACGTCTAAA CAACCAAAAG TAATTCCTGA TGATTTAGCC 2400'
CAGCAGAACC TAATTGTATC AAACACAGAA GCTCCTGGAG ATGACAAAGT GTATTCTGCG 2460
AATGGCTTCA CAACCCAAAC TGTGGGCGCT TCTGCTCAGG GAGTTTGTGG CACCGTGGGA 2520 TCAGGAATCA AAAACGGAGG TCAGGAGACC ATCGAAATGG TGAAAGGAGG ACACCAGACC 2580 TCGGAATCCT GCCGGGGGGC TGGCCACCAT CACACCCTGG ACTCCTGCAG GGGAGGACAC 2640 ACGGAGGTGG ACAACTGCAG ATACACTTAC TCGGAGTGGC ACAGTTTTAC TCAGCCCCGT 2700 CTTGGTGAAA AAGTGTATCT GTGTAATCAA GATGAAAATC ACAAGCATGC CCAAGACTAT 2760 GTCCTGACAT ATAACTATGA AGGAAGAGGA TCGGTGGCTG GGTCTGTAGG TTGTTGCAGT 2820 GAACGACAAG AAGAAGATGG GCTTGAATTT TTGGATAATT TGGAGCCCAA ATTTAGGACA 2880 CTAGCAGAAG CATGCATGAA GAGATGAGTG TGTTCTAATA AGTCTCTGAA AGCCAGTGGC 2940 TTTATGACTT TTAAAAAAAA TTACAAACCA AGAATTTTTT AAAGCAGAAG ATGCTATTTG 3000 TGGGGGTTTT TCTCTCATTA TTTGGATGGA ATCTCTTTGG TCAAATGCAC ATTTACAGAG 3060 AGACACTATA AACAAGTACA CAAATTTTTC AATTTTTACA TATTTTTAAA TTACTTATCT 3120 TCTATCCAAG GAGGTCTACA GAGAAATTAA AGTCTGCCTT ATTTGTTACA TTTGGGTATA 3180 ATGACAACAG CCAATTTATA GTGCAATAAA ATGTAATTAA TTCAAGTCCT TATTATAGAC 3240 TATTTGAAβC ACAACCTAAT GGAAAATTGT AGAGACCTTG CTTTAACATT ATCTCCAGTT 3300 AATTAAGTGT TCATGTGGTG CTTGGAAACT GTTGTTTTCC TGAACATCTA AAGTGTGTAG 3360 ACTGCATTCT TGCTATTATT TTATTCTTGT AATGTGACCT TTTCACTGTG CAAAGGGAGA 3420 TTTCTAGCCA GGCATTGACT ATTACAATTT CATT
Seq ID NO: 416 Protein sequence Protein Accesεion #: NP 077740.1
11 21 31 41 51
I I I I I
MEAARPSGSW NGALCRLLLL TLAILIFASD ACKNVTLHVP SKLDAEKLVG RVNLKECFTA 60 ANLIHSSDPD FQILEDGSVY TTNTILLSSE KRSFTILLSN TENQEKKKIF VFLEHQTKVL 120 KKRHTKEKVL RRAKRRWAPI PCSMLENSLG PFPLFLQQVQ SDTAQNYTIY YSIRGPGVDQ 180 EPRNLFYVER DTGNLYCTRP VDREQYESFE IIAFATTPDG YTPELPLPLI IKIEDENDNY 240 PIFTEETYTF TIFENCRVGT TVGQVCATDK DEPDTMHTRL KYSIIGQVPP SPTLFSMHPT 300 TGVITTTSSQ LDRELIDKYQ LKIKVQDMDG QYFGLQTTST CIINIDDVND HLPTFTRTSY 360 VTSVEENTVD VEILRVTVED KDLVNTANWR ANYTILKGNE NGNFKIVTDA KTNEGVLCW 420 KPLNYEEKQQ MILQIGWNE APFSREASPR SAMSTATVTV NVEDQDEGPE CNPPIQTVRM 480 KENAEVGTTS NGYKAYDPET RSSSGIRYKK LTDPTGWVTI DENTGSIKVF RSLDREAETI 540 KNGIYNITVL ASDQGGRTCT GTLGIILQDV NDNSPFIPKK TVIICKPTMS SAEIVAVDPD 600 EPIHGPPFDF SLESSTSEVQ RMWRLKAIND TAARLSYQND PPFGSYWPI TVRDRLGMSS 660 VTSLDVTLCD CITENDCTHR VDPRIGGGGV QLGKWAILAI LLGIALLFCI LFTLVCGASG 720 TSKQPKVIPD DLAQQNLIVS NTEAPGDDKV YSANGFTTQT VGASAQGVCG TVGSGIKNGG 780 QETIEMVKGG HQTSESCRGA GHHHTLDSCR GGHTEVDNCR YTYSEWHSFT QPRLGEKVYL 840 CNQDENHKHA QDYVLTYNYE GRGSVAGSVG CCSERQEEDG LEFLDNLEPK FRTLAEACMK 900 R
Seq ID NO: 417 DNA εequence
Nucleic Acid Accession #: NM_004949.1
Coding sequence: 202..2745
11 21 31 41 51
I I I
CGCCAAAGGA AAAGCCCCTT G 1GATGAGAGG CAGGCGCTTC AGAGAAGCTA AGAAAAGCAC 60 CTCTCCGCGC GCCCCACCTC CTCCGCCTCG CGCTCCTCCT GAGCAGCGGG CCCAGACTGC 120 GCTCCGGCCG CGGCCCTCGC CCCGCGGAGC CCTCCTACCC CGGCCCGACG CTCGGCCCGC 180 GACCTGCCCC GAGCCCTCTC CATGGAGGCA GCCCGCCCCT CCGGCTCCTG GAACGGAGCC 240 CTCTGCCGGC TGCTCCTGCT GACCCTCGCG ATCTTAATAT TTGCCAGTGA TGCCTGCAAA 300 AATGTGACAT TACATGTTCC CTCCAAACTA GATGCCGAGA AACTTGTTGG TAGAGTTAAC 360 CTGAAAGAGT GCTTTACAGC TGCAAATCTA ATTCATTCAA GTGATCCTGA CTTCCAAATT 420 TTGGAGGATG GTTCAGTCTA TACAACAAAT ACTATTCTAT TGTCCTCGGA GAAGAGAAGT 480 TTTACCATAT TACTTTCCAA CACTGAGAAC CAAGAAAAGA AGAAAATATT TGTCTTTTTG 540 GAGCATCAAA CAAAGGTCCT AAAGAAAAGA CATACTAAAG AAAAAGTTCT AAGGCGCGCC 600 AAGAGAAGAT GGGCTCCAAT TCCTTGTTCG ATGCTAGAAA ACTCCTTGGG TCCTTTTCCA 660 CTTTTCCTTC AACAGGTTCA ATCTGACACG GCCCAAAACT ATACCATATA CTATTCCATA 720 AGAGGTCCTG GAGTTGACCA AGAACCTCGG AATTTATTTT ATGTGGAGAG AGACACTGGA 780 AACTTGTATT GTACTCGTCC TGTAGATCGT GAGCAGTATG AATCTTTTGA GATAATTGCC 840 TTTGCAACAA CTCCAGATGG GTATACTCCA GAACTTCCAC TGCCCCTAAT AATCAAAATA 900 GAGGATGAAA ATGATAACTA CCCAATTTTT ACAGAAGAAA CTTATACTTT TACAATTTTT 960 GAAAATTGCA GAGTGGGCAC TACTGTGGGA CAAGTGTGTG CTACTGACAA AGATGAGCCT 1020 GACACGATGC ACACACGCCT GAAGTACTCC ATCATTGGGC AGGTGCCACC ATCACCCACC 1080 CTATTTTCTA TGCATCCAAC TACAGGCGTG ATCACCACAA CATCATCTCA GCTAGACAGA 1140 GAGTTAATTG ACAAGTACCA GTTGAAAATA AAAGTACAAG ACATGGATGG TCAGTATTTT 1200 GGTCTACAGA CAACTTCAAC TTGTATCATT AACATTGATG ATGTAAATGA CCACTTGCCA 1260 ACATTTACTC GTACTTCTTA TGTGACATCA GTGGAAGAAA ATACAGTTGA TGTGGAAATC 1320 TTACGAGTTA CTGTTGAGGA TAAGGACTTA GTGAATACTG CTAACTGGAG AGCTAATTAT 1380 ACCATTTTAA AGGGCAATGA AAATGGCAAT TTTAAAATTG TAACAGATGC CAAAACCAAT 1440 GAAGGAGTTC TTTGTGTAGT TAAGCCTTTG AATTATGAAG AAAAGCAACA GATGATCTTG 1500 CAAATTGGTG TAGTTAATGA AGCTCCATTT TCCAGAGAGG CTAGTCCAAG ATCAGCCATG 1560 AGCACAGCAA CAGTTACTGT TAATGTAGAA GATCAGGATG AGGGCCCTGA GTGTAACCCT 1620 CCAATACAGA CTGTTCGCAT GAAAGAAAAT GCAGAAGTGG GAACAACAAG CAATGGATAT 1680 AAAGCATATG ACCCAGAAAC AAGAAGTAGC AGTGGCATAA GGTATAAGAA ATTAACTGAT 1740 CCAACAGGGT GGGTCACCAT TGATGAAAAT ACAGGATCAA TCAAAGTTTT CAGAAGCCTG 1800 GATAGAGAGG CAGAGACCAT CAAAAATGGC ATATATAATA TTACAGTCCT TGCATCAGAC 1860 CAAGGAGGGA GAACATGTAC GGGGACACTG GGCATTATAC TTCAAGACGT GAATGATAAC 1920 AGCCCATTCA TACCTAAAAA GACAGTGATC ATCTGCAAAC CCACCATGTC ATCTGCGGAG 1980 ATTGTTGCGG TTGATCCTGA TGAGCCTATC CATGGCCCAC CCTTTGACTT TAGTCTGGAG 2040 AGTTCTACTT CAGAAGTACA GAGAATGTGG AGACTGAAAG CAATTAATGA TACAGCAGCA 2100 CGTCTTTCCT ATCAGAATGA TCCTCCATTT GGCTCATATG TAGTACCTAT AACAGTGAGA 2160 GATAGACTTG GCATGTCTAG TGTCACTTCA TTGGATGTTA CACTGTGTGA CTGCATTACC 2220 GAAAATGACT GCACACATCG TGTAGATCCA AGGATTGGCG GTGGAGGAGT ACAACTTGGA 2280 AAGTGGGCCA TCCTTGCAAT ATTGTTGGGC ATAGCATTGC TCTTTTGCAT CCTGTTTACG 2340 CTGGTCTGTG GGGCTTCTGG GACGTCTAAA CAACCAAAAG TAATTCCTGA TGATTTAGCC 2400
CAGCAGAACC TAATTGTATC AAACACAGAA GCTCCTGGAG ATGACAAAGT GTATTCTGCG 2460
AATGGCTTCA CAACCCAAAC TGTGGGCGCT TCTGCTCAGG GAGTTTGTGG CACCGTGGGA 2520
TCAGGAATCA AAAACGGAGG TCAGGAGACC ATCGAAATGG TGAAAGGAGG ACACCAGACC 2580
TCGGAATCCT GCCGGGGGGC TGGCCACCAT CACACCCTGG ACTCCTGCAG GGGAGGACAC 2640
ACGGAGGTGG ACAACTGCAG ATACACTTAC TCGGAGTGGC ACAGTTTTAC TCAGCCCCGT 2700
CTTGGTGAAG AATCCATTAG AGGACACACT CTGATTAAAA ATTAAACAAT GAAAGAAAGT 2760
GTATCTGTGT AATCAAGATG AAAATCACAA GCATGCCCAA GACTATGTCC TGACATATAA 2820
CTATGAAGGA AGAGGATCGG TGGCTGGGTC TGTAGGTTGT TGCAGTGAAC GACAAGAAGA 2880
AGATGGGCTT GAATTTTTGG ATAATTTGGA GCCCAAATTT AGGACACTAG CAGAAGCATG 2940
CATGAAGAGA TGAGTGTGTT CTAATAAGTC TCTGAAAGCC AGTGGCTTTA TGACTTTTAA 3000
AAAAAATTAC AAACCAAGAA TTTTTTAAAG CAGAAGATGC TATTTGTGGG GGTTTTTCTC 3060
TCATTATTTG GATGGAATCT CTTTGGTCAA ATGCACATTT ACAGAGAGAC ACTATAAACA 3120
AGTACACAAA TTTTTCAATT TTTACATATT TTTAAATTAC TTATCTTCTA TCCAAGGAGG 3180
TCTACAGAGA AATTAAAGTC TGCCTTATTT GTTACATTTG GGTATAATGA CAACAGCCAA 3240
TTTATAGTGC AATAAAATGT AATTAATTCA AGTCCTTATT ATAGACTATT TGAAGCACAA 3300
CCTAATGGAA AATTGTAGAG ACCTTGCTTT AACATTATCT CCAGTTAATT AAGTGTTCAT 3360
GTGGTGCTTG GAAACTGTTG TTTTCCTGAA CATCTAAAGT GTGTAGACTG CATTCTTGCT 3420
ATTATTTTAT TCTTGTAATG TGACCTTTTC ACTGTGCAAA GGGAGATTTC TAGCCAGGCA 3480 TTGACTATTA CAATTTCATT
Seq ID NO : 418 Protein sequence Protein Accession ft : NP_004940 .1
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MEAARPSGSW NGALCRLLLL TLAILIFASD ACKNVTLHVP SKLDAEKLVG RVNLKECFTA 60
ANLIHSSDPD FQILEDGSVY TTNTILLSSE KRSFTILLSN TENQEKKKIF VFLEHQTKVL 120
KKRHTKEKVL RRAKRRWAPI PCSMLENSLG PFPLFLQQVQ SDTAQNYTIY YSIRGPGVDQ 180
EPRNLFYVER DTGNLYCTRP VDREQYESFE IIAFATTPDG YTPELPLPLI IKIEDENDNY 240
PIFTEETYTF TIFENCRVGT TVGQVCATDK DEPDTMHTRL KYSIIGQVPP SPTLFSMHPT 300
TGVITTTSSQ LDRELIDKYQ LKIKVQDMDG QYFGLQTTST CI INIDDVND HLPTFTRTSY 360
VTSVEENTVD VEILRVTVED KDLVNTANWR ANYTILKGNE NGNFKIVTDA KTNEGVLCW 420
KPLNYEEKQQ MILQIG NE APFSREASPR SAMSTATVTV NVEDQDEGPE CNPPIQTVRM 480
KENAEVGTTS NGYKAYDPET RSSSGIRYKK LTDPTGWVTI DENTGSIKVF RSLDREAETI 540
KNGIYNITVL ASDQGGRTCT GTLGIILQDV NDNSPFIPKK TVIICKPTMS SAEIVAVDPD 600
EPIHGPPFDF SLESSTSEVQ RMWRLKAIND TAARLSYQND PPFGSYWPI TVRDRLGMSS 660
VTSLDVTLCD CITENDCTHR VDPRIGGGGV QLGKWAILAI LLGIALLFCI LFTLVCGASG 720
TSKQPKVIPD DLAQQNLIVS NTEAPGDDKV YSANGFTTQT VGASAQGVCG TVGSGIKNGG 780
QETIEMVKGG HQTSESCRGA GHHHTLDSCR GGHTEVDNCR YTYSEWHSFT QPRLGEESIR 840 GHTLIKN
Seq ID NO : 419 DNA sequence Nucleic Acid Accession ft : NM_002722 .1 Coding sequence : 14 . .301
1 11 21 31 41 SI
I I I I I I
ACTCTGGACT CCGGATGGCT GCCGCACGCC TCTGCCTCTC CCTGCTGCTC CTGTCCACCT 60
GCGTGGCTCT GTTACTACAG CCACTGCTGβ GTGCCCAGGG AGCCCCACTG GAGCCAGTGT 120
ACCCAGGGGA CAATGCCACA CCAGAGCAGA TGGCCCAGTA TGCAGCTGAT CTCCGTAGAT 180
ACATCAACAT GCTGACCAGG CCTAGGTATG GGAAAAGACA CAAAGAGGAC ACGCTGGCCT 240
TCTCGGAGTG GGGGTCCCCG CATGCTGCTG TCCCCAGGGA GCTCAGCCCG CTGGACTTAT 300
AATGCCACCT TCTGTCTCCT ACGACTCCAT GAGCAGCGCC AGCCCAGCTC TCCCCTCTGC 360
ACCCTTGGCT CTGGCCAAAG CTTGCTCCCT GCTCCCACAC AGGCTCAATA AAGCAAGTCA 420 AAGCC
Seq ID NO: 420 Protein sequence Protein Accession #: NP_002713.1
1 11 21 31 41 51
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MAAARLCLSL LLLSTCVALL LQPLLGAQGA PLEPVYPGDN ATPEQMAQYA ADLRRYINML 60 TRPRYGKRHK EDTLAFSEWG SPHAAVPREL SPLDL
Seq ID NO: 421 DNA sequence
Nucleic Acid Accession ft: NM_032545.1
Coding sequence: 46..718
1 11 21 31 41 51
A IAACTGATCT TICAATGCACT AIAGAGAAGGA GIACTCTCAAA CICAAAAATGA CICTGGAGGCA 60
CCATGTCAGG CTTCTGTTTA CGGTCAGTTT GGCATTACAG ATCATCAATT TGGGAAACAG 120
CTATCAAAGA GAGAAACATA ACGGCGGTAG AGAGGAAGTC ACCAAGCTTG CCACTCAGAA 180
GCACCGACAG TCACCGCTCA ACTGGACCTC CAGTCATTTC GGAGAGGTGA CTGGGAGCGC 240
CGAGGGCTGG GGGCCGGAGG AGCCGCTCCC CTACTCCCGG GCTTTCGGAG AGGGTGCGTC 300
CGCGCGGCCG CGCTGCTGCA GGAACGGCGG TACCTGCGTG CTGGGCAGCT TCTGCGTGTG 360
CCCGGCCCAC TTCACCGGCC GCTACTGCGA GCATGACCAG AGGCGCAGTG AATGCGGCGC 420
CCTGGAGCAC GGAGCCTGGA CCCTCCGCGC CTGCCACCTC TGCAGCTGCA TCTTCGGGGC 480
CCTGCACTGC CTCCCCCTCC AGACGCCTGA CCGCTGTGAC CCGAAAGACT TCCTGGCCTC 540
CCACGCTCAC GGGCCGAGCG CCGGGGGCGC GCCCAGCCTG CTACTCTTGC TGCCCTGCGC 600
ACTCCTGCAC CGCCTCCTGC GCCCGGATGC GCCCGCGCAC CCTCGGTCCC TGGTCCCTTC 660
CGTCCTCCAG CGGGAGCGGC GCCCCTGCGG AAGGCCGGGA CTTGGGCATC GCCTTTAATT 720
TTCTATGTTG TAAATAATAG ATGTGTTTAG TTTACCGTAA GCTGAAGCAC TGGGTGAATA 780 TTTTTATTGG GTAATAAATA TTTTCATGAA AGCGCCAAAA AAAAAAAAAA AAAAAAAAAA 840 AAAAAA
Seq ID NO: 422 Protein sequence Protein Accesεion # NP 115934.1
1 11 21 31 41 51
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MTWRHHVRLL FTVSLALQII NLGNSYQREK HNGGREEVTK VATQKHRQSP LNWTSSHFGE 60 VTGSAEGWGP EEPLPYSRAF GEGASARPRC CRNGGTCVLG SFCVCPAHFT GRYCEHDQRR 120
SECGALEHGA WTLRACHLCR CIFGALHCLP LQTPDRCDPK DFLASHAHGP SAGGAPSLLL 180 LLPCALLHRL LRPDAPAHPR SLVPSVLQRE RRPCGRPGLG HRL
Seq ID NO : 423 DNA sequence Nucleic Acid Accession # : NM_006533 .1
Coding sequence : 72 . .467
60
120
Figure imgf001121_0001
180
CGGACCAGGA GTGCAGCCAC CCTATCTCCA TGGCTGTGGC CCTTCAGGAC TACATGGCCC 240
CCGACTGCCG ATTCCTGACC ATTCACCGGG GCCAAGTGGT GTATGTCTTC TCCAAGCTGA 300
AGGGCCGTGG GCGGCTCTTC TGGGGAGGCA GCGTTCAGGG AGATTACTAT GGAGATCTGG 360
CTGCTCGCCT GGGCTATTTC CCCAGTAGCA TTGTCCGAGA GGACCAGACC CTGAAACCTG 420
GCAAAGTCGA TGTGAAGACA GACAAATGGG ATTTCTACTG CCAGTGAGCT CAGCCTACCG 480
CTGGCCCTGC CGTTTCCCCT CCTTGGGTTT ATGCAAATAC AATCAGCCCA GTGCAAAC
Seq ID NO: 424 Protem sequence
Protein Accession #: NP_006524.1
1 11 21 31 41 51
1
MARSLVCLGV I1ILLSAFSGP G1VRGGPMPKL A1DRKLCADQE C1SHPISMAVA L1QDYMAPDCR 60
FLTIHRGQW YVFSKLKGRG RLFWGGSVQG DYYGDLAARL GYFPSSIVRE DQTLKPGKVD 120 VKTDKWDFYC Q
Seq ID NO : 425 DNA sequence Nucleic Acid Accession it : NM_080870 .1
Coding sequence : 3 . .710
11 21 31 41 51
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AGATGACACA AGTCACAGAA AAGTCCACAG AACACCCAGA AAAGACCACG TCAACCACAG 60 AGAAAACCAC AAGAACCCCA GAAAAGCCTA CGCTATACTC AGAGAAGACC ATATGCACCA 120 AAGGGAAAAA CACACCAGTC CCAGAAAAGC CTACAGAAAA CCTGGGGAAC ACCACACTGA 180 CCACTGAGAC CATAAAAGCC CCAGTAAAGT CCACAGAAAA CCCAGAAAAA ACAGCAGCAG 240 TCACAAAGAC TATAAAACCT TCAGTCAAGG TCACAGGAGA CAAATCTCTC ACTACTACCT 300 CTTCTCATCT AAATAAAACT GAAGTTACTC ATCAGGTGCC CACTGGTTCT TTCACCCTCA 360 TTACATCTAG AACGAAGCTG AGTTCTATCA CATCAGAAGC CACAGGAAAC GAGAGCCATC 420 CATACCTCAA TAAAGATGGC TCACAGAAAG GTATCCACGC TGGACAGATG GGAGAGAATG 480 ATTCATTCCC TGCATGGGCC ATAGTTATTG TGGTCCTGGT GGCTGTGATT CTCCTCCTGG 540 TGTTCCTTGG CCTGATCTTC TTGGTCTCCT ATATGATGCG GACACGCCGC ACACTAACCC 600 AGAACACCCA GTACAATGAT GCAGAGGATG AGGGTGGCCC CAATTCCTAC CCGGTCTACC 660 TGATGGAGCA GCAGAATCTT GGCATGGGCC AGATCCCTTC CCCACGGTGA TCTTGGAGTA 720 GGCGCCCAGC CCTGGCTCTT CCATGCTCTG CCCCTTTCCT GGATGAGGAA CCGGACTCAC 780 AATTTCTATT TCCGGGACTA CAGGAAGGGC AGAGAATACT GACGGTTACC AGTATTAACC 840 CTTCATCTGT TCTTGAAACT GGTTGGGGAA TGAGGTGATA AGCAAGGAGG GTGTAAGTTT 900 AGGGGACAAA GAAGAAAGAA TGAATAATAC GAGCAGACAT TCTCTGTAGA AGGTAATGGT 960 CTGAGAATGA AAAGGTGTTT GATGGACATG TTGTGGGGGC ACCAATGCAG AACACTGCAC 1020 TGAGTCCTAA AGGAAGGACA GGAGCCTTAT AGGCAATGCC CCAGACTGAC TTGTGAGTGG 1080 GGTTTATGGG GAAAGGGAGG GACTGAGGGC AGAGTCTCTG GGTTTCAGGA CAGCATTATG 1140 TTATTTCCAT TCACTATTAC TTAAGAGTTT GTGTGTAAAC AGGCTCATCT CTGAGTTCTC 1200 AGGACCCTTG CCCCCACCGC CATTTTTTTA ATGAAAAAAA AAAACAAAAA AAACGGATCC 1260 AAGAAGAAAA GAGAATTTAT TTCCTTCTCC ACTCTCTCCA TGCCCTGGAG AAAAAAAAGT 1320 CCAGAAGAAA TCATAAATAT CTCTCATCTA CATGGTTGCT TCCTCTTCCT CCCAAATCCC 1380 TTAGTTTTCC TAAATGTCTA CAGTGGACGC CCTGTTGGTT TGGCTTGCTG GGTTGTGGGT 1440 GGACACGCAA GGAGGGGATT TTTATTTGGC CAGCAGTCTC ACCCACTGAT CTCCACCCCA 1500 GACCTTCCCT GATTGGTGTC TCAGCATTTA TTTTCCTGTC TCTTCCACCA AAAGCCAGCT 1560 GTAGCTTTAT CTCGTAAAAG TTACCCATCT TCTCTACTGT CCCCATTCTC TCTCCTCCCA 1620 CCTTCACCCC AGATTCAAGT TTTCCTCCTT GTAGGCATTT CATCTGTGTG TGTTTTCTGG 1680 ATTTTCTCTC TCTCTTCTTA TGGCCATTTC ACCTTATTAC TGATTGGGTA GAGGGGGAAA 1740 AGGAGAATGA TGATGATAGT TTCCTTCTGT CTATTGACCT TTTTTATAAT AAAGTATAAC 1800 ATGTT
Seq ID NO: 426 Protein sequence Prote Accession ft: NP_543146.1
1 11 21 31 41 51
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MTQVTEKSTE HPEKTTSTTE KTTRTPEKPT LYSEKTICTK GKNTPVPEKP TENLGNTTLT 60 TETIKAPVKS TENPEKTAAV TKTIKPSVKV TGDKSLTTTS SHLNKTEVTH QVPTGSFTLI 120 TSRTKLSSIT SEATGNESHP YLNKDGSQKG IHAGQMGEND SFPAWAIVIV VLVAVILLLV 180 FLGLIFLVSY MMRTRRTLTQ NTQYNDAEDE GGPNSYPVYL MEQQNLGMGQ IPSPR
Seq ID NO: 427 DNA sequence Nucleic Acid Accession #: XM_069480.1 Coding sequence: 1..4383
11 21 31 41 51
ATGGACACTG TGCTGGTGCT GCTCCTGGGC CTGCAGGCCT TGGCCGGACC CAGTCCGAAG 60
CCCCAGAAGG ACTCTGTCTC AGACTGGGCC ATTGTGTTGA TCACTCTCAC TTTGGTGGCA 120
GCAATTGTCA GCCTAATGTA CGGTATCAAG AAGGCCTGCC AGTTCCGGAG GGAGATGAGT 180
CTGGGGTGTG GCTGTGGCTC TGTGACCCCT TACAGCAGCC ACCATGAGGG GGAGGCTGCC 240
AGCCAGCGCT ACTCTTGTCA AATGAAAGCT TCTTGGGGGβ CAGGTGCTAC TACATTCCAA 300
GAATATCAGA AAACTGGGGA ACTCTCAACA TCCGATCACA TATTTCCCCT CACTCCAGGC 360
CTTGTTTATA GTATCCCTTT TGATCACATT GTTCTGCATT CAGGACAAAG ACCTCCAGAG 420
CTCCCTAAAT CTACAGAAAT CCATGAGCAA AAACGCCACT GCAACACCAC ACGCCATTCT 480
AAGCCAACTG ACAAGCCTAC AGGCAACTCC AAAACTATAG ACCACAAAAG CTCTACAGAT 540
AATCATGAGG CTCCTCCCAC TTCTGAAGAA AACTCCAGCA ACCAAGGGAA AGACCCAATG 600
ATCCGGAACC AGCGCTCTGT TGATCCTGCT GACTCCACTA CCACACATAA AGAATCCGCT 660
GGAAAAAAAC ATATAACGCC AGCACCCAAG AGCAAAATAA ACTGTCGTAA GTCCACAACA 720
GGCAAATCAA CGGTAACAAG AAAATCAGAT AAAACTGGAA GACCTTTGGA AAAGTCCATG 780
AGTACTTTGG ATAAGACAAG TACCAGCTCA CATAAGACTA CAACTTCCTT CCACAACTCA 840
GGCAATTCAC AGACCAAGCA AAAAAGCACA TCTTTTCCAG AAAAAATCAC AGCAGCCTCA 900
AAAACAACAT ACAAGACCAC AGGAACCCCA GAAGAGTCAG AAAAAACTGA AGATTCCAGA 960
ACAACAGTTG CCTCAGACAA GCTCCTGACA AAAACTACAA AAAACATACA AGAGACCATA 1020
TCAGCCAATG AGCTCACACA ATCTCTAGCA GAGCCTACAG AACATGGAGG AAGGACAGCC 1080
AATGAGAACA ACACACCATC CCCAGCAGAG CCTACAGAAA ATAGAGAAAG GACAGCCAAT 1140
GAGAACACCA CACTATCCCC AGCAGAGCCT ACAGAAAATA GAGAAAGGAC AGCCAATGAG 1200
AACACCGCAC CATTCCCAGC AGGGCCTACA GAAAATAGAG AAATGACAGC CAATGAGAAT 1260
ACCACACTAT TCCCAGCAGA GCCTACAGAA CATGGAGAAA GGACAGCCAA TGAGAACACC 1320
ACACCATCCC CAGCAGAGCC TACAGAACAT GGAGAAAGGA CAGCCAATGA GAACACTACA 1380
CCATCCCCAG CAGAGCCTAC AGAACATGGA GAAAGGACCC CATTTGCCAA TGACAAAACC 1440
ACATCATCCT CAGCAGAGTC TACAGAACAT GGAGAAAGGA CCCCACTGGC CAACGAGAAC 1500
ACCACACCAT CCCCAGCAGA GCCTACAGAA AATAGAGAAA GGACAGCCAA TGAGAACACC 1560
ACACCATCCC CAGCAGGGCC TACAGAAAAC AGAGAAACGA CAGCCAACGA GAAGACCACA 1620
CTATCCCCAG TAGAGCCTAC AGAAAATAGA GAAACAACAG CCAATGAGAA GACCACACCA 1680
TCCCCAGCAG AGCCTACAGA AAATGGACAA AGGACCCCAT TTGCCAATGA GAAAACCACA 1740
TCATCCTCAG CAGAGCCTAC AGAACACGGA GAAAGGACCC CACTGGCCAA TGAGAACACC 1800
ACACCATCCC CAGCAGAGCC TACAGAAAAT AGAGAAAGGA CAGCCAATGA GAAGACCACA 1860
CCATCCCCAG CAGAGCCTAC AGAAAATGGA GACAGGACTC CTTTGGCCAA TGAGAAGACC 1920
ACGCCATCTC TAGCAGAGCC TACAGAAAAT GGACAAAGGA CCCCATTTGC CAATGAGAAG 1980
ACCACATCAT CCTCAGCAGA GCCTACAGAA CACGAAGAAA GGACTCCACT GGCCAATGAG 2040
AACACCACAC CATCCCCGGC AGAGCCTACA GAAAATAGAG AAAGGACAGC CAATGAGAAC 2100
ACCACACCAT CCCCAGCAGG GCCTACAGAA AATAGAGAAA TGACAGCCAA CGAGAAGACC 2160
ACACTATTCC CAGCAGAGCC TACAGAAAAT AGAGAAAGGA CAGCCAATGA GAAGACCACA 2220
TCATCCCCAβ CAGAGCCTAC AGAAAATGGA CAAAGGACCC CATTTGCCAA TGAGAAAACC 2280
ACATCATCCC CAGCAGAGCC TACAGAACAC GGAGAAAGGA CCCCACTGGC CAATGAGAAC 2340
ACCACACTAT CCCCAGCAGA GCCTACAGAA AATAGAGAAA GGACAGCCAA TGAGAAGACC 2400
ACACCATTCC CAGCAGAGCC TACAGAAAAT AGAGAAAGGA CAGCCAATGA GAACACCACA 2460
CCATCCCCAG CACAGCCTAC AGAAAATGGA GACAGGACTC CATTGGCCAA TGAGAAGACC 2520
ACACCATCTC TAGCAGAGCC TACAGAAAAT GGAAAAAGGA CCCCATTTGC CAATGAGAAG 2580
ACCACATCAT CCTCAGCAGA GCCTACAGAA CACGCAGAAA GGACTCCACT GGCCAATGAG 2640
AACACCACAT CATCCCCAGC AGAGCCTACA GAAAATAGAG AAAGGACAGC CAATGAGAAG 2700
ACCACACAAT TCCCAGCAGA GCCTACAGAA AATAGAGAAA GCACAGCCAA TGAGAAGACC 2760
ACACCATTCC CAGCAβAGCC TACAGAAAAT AGAGAATGGA CAGCCAATGA GAACACCACA 2820
CTATCCCCAG CAGAβCCTAC AGAACATGAA GAAATGACCC CATTGGCCAA TGAGAAGACC 2880
ACACTATCCC CAGCAGAGCC TACAGAAAAT GGAGAAAGGA CCCCATTTAC CAATGAGAAG 2940
ACCACACCAT CCTCAGCAGA GCCTACAGAA CATGGAGAAA GGACCCCACT GGCCAATGAG 3000
ATCACCACAC CATCCCGAGC AGAGCCTACA GAACATGGAG AAAGGATAGC CAATGAGAAG 3060
GCCACACCAT CCCCAGCAAA GCCTACAGAA CATGGAGAAA CGACAGTCAA TGAGGACACC 3120
ACACCATCCT CAGCAGAGCC TACAGAAAAT GGAGAAAGGA CCCCACTGGC CAATGAGAAC 3180
ACCACAACAT CCCCAACAGA GTCTACAGAA CATGGAGAAA GGACAGCCAA TGAGAAGACC 3240
ACACCATCCC CAGCAGAGCC TACAGAACAT GGAGAAAGGA CACCATCAGC CAATGAGAAG 3300
ACCATACCAT CTCCAGCAAA GCCTACAGAA CACGAAGAAA TGACCCCATC GGCCAATGAG 3360
AACACCACAC CATCCCCAGT AAAGCCTACA GAACATGGAG AAAAGACTAC ATTGGCCAAT 3420
GAGAAGATCA CACTATCCCC AGAAGGGCCT ACAGAACATG GAGCAAAAAC TACGTCGGCC 3480
AATGAGAAGA TCACACCATC CCTAGCAAAG CCTACAGAAC ATGGAGAAAG GACCACATCA 3540
CCCAATGACA AGATCACCTC ATCTGCAGCA GAGTCTACAG AACATAGAGA TAGGGCTACA 3600
TCAGCCAATG TGATCACACC AGCCCCAGCA GAGCCTATAA AACATGCAAA AAGGACCACA 3660
TTGGCCCATG AGAAGATGAC ACAAGTCACA GAAAAGTCCA CAGAACACCC AGAAAAGACC 3720
ACGTCAACCA CAGAGAAAAC CACAAGAACC CCAGAAAAGC CTACGCTATA CTCAGAGAAG 3780
ACCATATGCA CCAAAGGGAA AAACACACCA GTCCCAGAAA AGCCTACAGA AAACCTGGGG 3840
AACACCACAC TGACCACTGA GACCATAAAA GCCCCAGTAA AGTCCACAGA AAACCCAGAA 3900
AAAACAGCAG CAGTCACAAA GACTATAAAA CCTTCAGTCA AGGTCACAGG AGACAAATCT 3960
CTCACTACTA CCTCTTCTCA TCTAAATAAA ACTGAAGTTA CTCATCAGGT GCCCACTGGT 4020
TCTTTCACCC TCATTACATC TAGAACGAAG CTGAGTTCTA TCACATCAGA AGCCACAGGA 4080
AACGAGAGCC ATCCATACCT CAATAAAGAT GGCTCACAGA AAGGTATCCA CGCTGGACAG 4140
ATGGGAGAGA ATGATTCATT CCCTGCATGG GCCATAGTTA TTGTGGTCCT GGTGGCTGTG 4200
ATTCTCCTCC TGGTGTTCCT TGGCCTGATC TTCTTGGTCT CCTATATGAT GCGGACACGC 4260
CGCACACTAA CCCAGAACAC CCAGTACAAT GATGCAGAGG ATGAGGGTGG CCCCAATTCC 4320
TACCCGGTCT ACCTGATGGA GCAGCAGAAT CTTGGCATGG GCCAGATCCC TTCCCCACGG 4380 TGA Seq ID NO: 428 Protein sequence Protein Accession ft: XP 069480.1
11 21 31 41 51
I I I I I
MDTVLVLLLG LQALAGPSPK PQKDSVSDWA IVLITLTLVA AIVSLMYGIK KACQFRREMS 60 LGCGCGSVTP YSSHHEGEAA SQRYSCQMKA SWGAGATTFQ EYQKTGELST SDHIFPLTPG 120 LVYSIPFDHI VLHSGQRPPE LPKSTEIHEQ KRHCNTTRHS KPTDKPTGNS KTIDHKSSTD 180 NHEAPPTSEE NSSNQGKDPM IRNQRSVDPA DSTTTHKESA GKKHITPAPK SKINCRKSTT 240 GKSTVTRKSD KTGRPLEKSM STLDKTSTSS HKTTTSFHNS GNSQTKQKST SFPEKITAAS 300 KTTYKTTGTP EESEKTEDSR TTVASDKLLT KTTKNIQETI SANELTQSLA EPTEHGGRTA 360 NENNTPSPAE PTENRERTAN ENTTLSPAEP TENRERTANE NTAPFPAGPT ENREMTANEN 420 TTLFPAEPTE HGERTANENT TPSPAEPTEH GERTANENTT PSPAEPTEHG ERTPFANDKT 480 TSSSAESTEH GERTPLANEN TTPSPAEPTE NRERTANENT TPSPAGPTEN RETTANEKTT 540 LSPVEPTENR ETTANEKTTP SPAEPTENGQ RTPFANEKTT SSSAEPTEHG ERTPLANENT 600 TPSPAEPTEN RERTANEKTT PSPAEPTENG DRTPLANEKT TPSLAEPTEN GQRTPFANEK 660 TTSSSAEPTE HEERTPLANE NTTPSPAEPT ENRERTANEN TTPSPAGPTE NREMTANEKT 720 TLFPAEPTEN RERTANEKTT SSPAEPTENG QRTPFANEKT TSSPAEPTEH GERTPLANEN 780 TTLSPAEPTE NRERTANEKT TPFPAEPTEN RERTANENTT PSPAQPTENG DRTPLANEKT 840 TPSLAEPTEN GKRTPFANEK TTSSSAEPTE HAERTPLANE NTTSSPAEPT ENRERTANEK 900 TTQFPAEPTE NRESTANEKT TPFPAEPTEN REWTANENTT LSPAEPTEHE EMTPLANEKT 960 TLSPAEPTEN GERTPFTNEK TTPSSAEPTE HGERTPLANE ITTPSRAEPT EHGERIANEK 1020 ATPSPAKPTE HGETTVNEDT TPSSAEPTEN GERTPLANEN TTTSPTESTE HGERTANEKT 1080 TPSPAEPTEH GERTPSANEK TIPSPAKPTE HEEMTPSANE NTTPSPVKPT EHGEKTTLAN 1140 EKITLSPEGP TEHGAKTTSA NEKITPSLAK PTEHGERTTS PNDKITSSAA ESTEHRDRAT 1200 SANVITPAPA EPIKHAKRTT LAHEKMTQVT EKSTEHPEKT TSTTEKTTRT PEKPTLYSEK 1260 TICTKGKNTP VPEKPTENLG NTTLTTETIK APVKSTENPE KTAAVTKTIK PSVKVTGDKS 1320 LTTTSSHLNK TEVTHQVPTG SFTLITSRTK LSSITSEATG NESHPYLNKD GSQKGIHAGQ 1380 MGENDSFPAW AIVIWLVAV ILLLVFLGLI FLVSYMMRTR RTLTQNTQYN DAEDEGGPNS 1440 YPVYLMEQQN LGMGQIPSPR
Seq ID NO: 429 DNA sequence
Nucleic Acid Accession #: FGENESH predicted
Coding sequence: 1..10674
11 21 31 41 51
I I I I I
ATGTGGCCTC GCCTGGCCTT TTGTTGCTGG GGTCTGGCGC TCGTTTCGGG CTGGGCGACC 60
TTTCAGCAGA TGTCCCCGTC GCGCAATTTC AGCTTCCGCC TCTTCCCCGA GACCGCGCCC 120
GGGGCCCCCG GGAGTATCCC CGCGCCGCCC GCTCCTGGCG ACGAAGCGGC GGGGAGCAGA 180
GTGGAGCGGC TGGGCCAGGC GTTCCGGCGA CGCGTGCGGC TGCTGCGGGA GCTCAGCGAG 240
CGCCTGGAGC TTGTCTTCCT GGTGGATGAT TCGTCCAGCG TGGGCGAAGT CAACTTCCGC 300
AGCGAGCTCA TGTTCGTCCG CAAGCTGCTG TCCGACTTCC CCGTGGTGCC CACGGCCACG 360
CGCGTGGCCA TCGTGACCTT CTCGTCCAAG AACTACGTGG TGCCGCGCGT CGATTACATC 420
TCCACCCGCC GCGCGCGCCA GCACAAGTGC GCGCTGCTCC TCCAAGAGAT CCCTGCCATC 480
TCCTACCGAG GTGGCGGCAC CTACACCAAG GGCGCCTTCC AGCAAGCCGC GCAAATTCTT 540
CTTCATGCTA GAGAAAACTC AACAAAAGTT GTATTTCTCA TCACTGATGG ATATTCCAAT 600
GGGGGAGACC CTAGACCAAT TGCAGCGTCA CTGCGAGATT CAGGAGTGGA GATCTTCACT 660
TTTGGCATAT GGCAAGGGAA CATTCGAGAG CTGAATGACA TGGCTTCCAC CCCAAAGGAG 720
GAGCACTGTT ACCTGCTACA CAGTTTTGAA GAATTTGAGG CTTTAGCTCβ CCGGGCATTG 780
CATGAAGATC TACCTTCTGG GAGTTTTATT CAAGATGATA TGGTCCACTG CTCATATCTT 840
TGTGATGAAG GCAAGGACTG CTGTGACCGA ATGGGAAGCT GCAAATGTGG GACACACACA 900
GGCCATTTTG AGTGCATCTG TGAAAAGGGG TATTACGGGA AAGGTCTGCA GTATGAATGC 960
ACAGCTTGCC CATCGGGGAC ATACAAACCT GAAGGCTCAC CAGGAGGAAT CAGCAGTTGC 1020
ATTCCATGTC CTGATGAAAA TCACACCTCT CCACCTGGAA GCACATCCCC TGAAGACTGT 1080
GTCTGCAGAG AGGGATACAG GGCATCTGGC CAGACCTGTG AACTTGTCCA CTGCCCTGCC 1140
CTGAAGCCTC CCGAAAATGG TTACTTTATC CAAAACACTT GCAACAACCA CTTCAATGCA 1200
GCCTGTGGGG TCCGATGTCA CCCTGGATTT GATCTTGTGG GAAGCAGCAT CATCTTATGT 1260
CTACCCAATG GTTTGTGGTC CGGTTCAGAG AGCTACTGCA GAGTAAGAAC ATGTCCTCAT 1320
CTCCGCCAGC CGAAACATGG CCACATCAGC TGTTCTACAA GGGAAATGTT ATATAAGACA 1380
ACATGTTTGG TTGCCTGTGA TGAAGGGTAC AGACTAGAAG GCAGTGATAA GCTTACTTGT 1440
CAAGGAAACA GCCAGTGGGA TGGGCCAGAA CCCCGGTGTG TGGAGCGCCA CTGTTCCACC 1500
TTTCAGATGC CCAAAGATGT CATCATATCC CCCCACAACT GTGGCAAGCA GCCAGCCAAA 1560
TTTGGGACGA TCTGCTATGT AAGTTGCCGC CAAGGGTTCA TTTTATCTGG AGTCAAAGAA 1620
ATGCTGAGAT GTACCACTTC TGGAAAATGG AATGTCGGAG TTCAGGCAGC TGTGTGTAAA 1680
GACGTGGAGG CTCCTCAAAT CAACTGTCCT AAGGACATAG AGGCTAAGAC TCTGGAACAG 1740
CAAGATTCTG CCAATGTTAC CTGGCAGATT CCAACAGCTA AAGACAACTC TGGTGAAAAG 1800
GTGTCAGTCC ACGTTCATCC AGCTTTCACC CCACCTTACC TTTTCCCAAT TGGAGATGTT 1860
GCTATCGTAT ACACGGCAAC TGACCTATCC GGCAACCAGG CCAGCTGCAT TTTCCATATC 1920
AAGGTTATTG ATGCAGAACC ACCTGTCATA GACTGGTGCA GATCTCCACC TCCCGTCCAG 1980
GTCTCGGAGA AGGTACATGC CGCAAGCTGG GATGAGCCTC AGTTCTCAGA CAACTCAGGG 2040
GCTGAATTGG TCATTACCAG AAGTCATACA CAAGGAGACC TTTTCCCTCA AGGGGAGACT 2100
ATAGTACAGT ATACAGCCAC TGACCCCTCA GGCAATAACA GGACATGTGA TATCCATATT 2160
GTCATAAAAG GTTCTCCCTG TGAAATTCCA TTCACACCTG TAAATGGGGA TTTTATATGC 2220
ACTCCAGATA ATACTGGAGT CAACTGTACA TTAACTTGCT TGGAGGGCTA TGATTTCACA 2280
GAAGGGTCTA CTGACAAGTA TTATTGTGCT TATGAAGATG GCGTCTGGAA ACCAACATAT 2340
ACCACTGAAT GGCCAGACTG TGCCAAAAAA CGTTTTGCAA ACCACGGGTT CAAGTCCTTT 2400
GAGATGTTCT ACAAAGCAGC TCGTTGTGAT GACACAGATC TGATGAAGAA GTTTTCTGAA 2460
GCATTTGAGA CGACCCTGGG AAAAATGGTC CCATCATTTT GTAGTGATGC AGAGGACATT 2520
GACTGCAGAC TGGAGGAGAA CCTGACCAAA AAATATTGCC TAGAATATAA TTATGACTAT 2580
GAAAATGGCT TTGCAATTGG ACCAGGTGGC TGGGGTGCAβ CTAATAGGCT GGATTACTCT 2640
TACGATGACT TCCTGGACAC TGTGCAAGAA ACAGCCACAA GCATCGGCAA TGCCAAGTCC 2700
TCACGGATTA AAAGAAGTGC CCCATTATCT GACTATAAAA TTAAGTTAAT TTTTAACATC 2760
ACAGCTAGTG TGCCATTACC CGATGAAAGA AATGATACCC TTGAATGGGA AAATCAGCAA 2820 CGACTCCTTC AGACATTGGA AACTATCACA AATAAACTGA AAAGGACTCT CAACAAAGAC 2880 CCCATGTATT CCTTTCAGCT TGCATCAGAA ATACTTATAG CCGACAGCAA TTCATTAGAA 2940 ACAAAAAAGG CTTCCCCCTT CTGCAGACCA GGCTCAGTGC TGAGAGGGCG TATGTGTGTC 3000 AATTGCCCTT TGGGAACCTA TTATAATCTG GAACATTTCA CCTGTGAAAG CTGCCGGATC 3060 GGATCCTATC AAGATβAAGA AGGGCAACTT GAGTGCAAGC TTTGCCCCTC TGGGATGTAC 3120 ACGGAATATA TCCATTCAAG AAACATCTCT GATTGTAAAG CTCAGTGTAA ACAAGGCACC 3180 TACTCATACA GTGGACTTGA GACTTGTGAA TCGTGTCCAC TGGGCACTTA TCAGCCAAAA 3240 TTTGGTTCCC GGAGCTGCCT CTCGTGTCCA GAAAACACCT CAACTGTGAA AAGAGGAGCC 3300 GTGAACATTT CTGCATGTGG AGTTCCTTGT CCAGAAGGAA AATTCTCGCG TTCTGGGTTA 3360 ATGCCCTGTC ACCCATGTCC TCGTGACTAT TACCAACCTA ATGCAGGGAA GGCCTTCTGC 3420 CTGGCCTGTC CCTTTTATGG AACTACCCCA TTCGCTGGTT CCAGATCCAT CACAGAATGT 3480 TCAACTTCAG TTCTGAATAT TACTATTTTC GGTGGATTTG GGCATCTGGA GTTGTTAAAT 3540 TGTCCTTCTG AGGTTTTCCA TGAATGCTTC TTTAACCCTT GCCACAATAG TGGAACCTGC 3600 CAGCAACTTG GGCGTGGTTA TGTTTGTCTC TGTCCACTTG GATATACAGG CTTAAAGTGT 3660 GAAACAGACA TCGATGAGTG CAGCCCACTG CCTTGCCTCA ACAATGGAGT TTGTAAAGAC 3720 CTAGTTGGGG AATTCATTTG TGAGTGCCCA TCAGGTTACA CAGGTCAGCG GTGTGAAGAA 3780 AATATAAATG AGTGTAGCTC CAGTCCTTGT TTAAATAAAG GAATCTGTGT TGATGGTGTG 3840 GCTGGCTATC GTTGCACATG TGTGAAAGGA TTTGTAGGCC TGCATTGTGA AACAGAAGTC 3900 AATGAATGCC AGTCAAACCC ATGCTTAAAT AATGCAGTCT GTGAAGACCA GGTTGGGGGA 3960 TTCTTGTGCA AATGCCCACC TGGATTTTTG GGTACCCGAT GTGGAAAGAA CGTCGATGAG 4020 TGTCTCAGTC AGCCATGCAA AAATGGAGCT ACCTGTAAAG ACGGTGCCAA TAGCTTCAGA 4080 TGCCTGTGTβ CAGCTGGCTT CACAGGATCA CACTGTGAAT TGAACATCAA TGAATGTCAG 4140 TCTAATCCAT GTAGAAATCA GGCCACCTGT GTGGATGAAT TAAATTCATA CACTTGTAAA 4200 TGTCAGCCAG GATTTTCAGG CAAAAGGTGT GAAACAGAAC AGTCTACAGG CTTTAACCTG 4260 GATTTTGAAG TTTCTGGCAT CTATGGATAT GTCATGCTAG ATGGCATGCT CCCATCTCTC 4320 CATGCTCTAA CCTGTACCTT CTGGATGAAA TCCTCTGACG ACATGAACTA TGGAACACCA 4380 ATCTCCTATG CAGTTGATAA CGGCAGCGAC AATACCTTGC TCCTGACTGA TTATAACGGC 4440 TGGGTTCTTT ATGTGAATGG CAGGGAAAAG ATAACAAACT GTCCCTCGGT GAATGATGGC 4500 AGATGGCATC ATATTGCAAT CACTTGGACA AGTGCCAATG GCATCTGGAA AGTCTATATC 4560 GATGGGAAAT TATCTGACGG TGGTGCTGGC CTCTCTGTTG GTTTGCCCAT ACCTGGTGGT 4620 GGTGCGTTAG TTCTGGGGCA AGAGCAAGAC AAAAAAGGAG AGGGATTCAG CCCAGCTGAG 4680 TCTTTTGTGG GCTCCATAAG CCAGCTCAAC CTCTGGGACT ATGTCCTGTC TCCACAGCAG 4740 GTGAAGTCAC TGGCTACCTC CTGCCCAGAG GAACTCAGTA AAGGAAACGT GTTAGCATGG 4800 CCTGATTTCT TGTCAGGAAT TGTGGGGAAA GTGAAGATCG ATTCTAAGAG CATATTTTGT 4860 TCTGATTGCC CACGCTTAGG AGGGTCAGTG CCTCATCTGA GAACTGCATC TGAAGATTTA 4920 AAGCCAGGTT CCAAAGTCAA TCTGTTCTGT GATCCAGGCT TCCAGCTGGT CGGGAACCCT 4980 GTGCAGTACT GTCTGAATCA AGGACAGTGG ACACAACCAC TTCCTCACTG TGAACGCATT 5040 AGCTGTGGGG TGCCACCTCC TTTGGAGAAT GGCTTCCATT CAGCCGATGA CTTCTATGCT 5100 GGCAGCACAG TAACCTACCA GTGCAACAAT GGCTACTATC TATTGGGTGA CTCAAGGATG 5160 TTCTGTACAG ATAATGGGAG CTGGAACGGC GTTTCACCAT CCTGCCTTGA TGTCGATGAG 5220 TGTGCAGTTG GATCAGATTG TAGTGAGCAT GCTTCTTGCC TGAACGTAGA TGGATCCTAC 5280 ATATGTTCAT GTGTCCCACC GTACACAGGA GATGGGAAAA ACTGTGCAGA ACCTATAAAA 5340 TGTAAGGCTC CAGGAAATCC GGAAAATGGC CACTCCTCAG GTGAGATTTA TACAGTAGGT 5400 GCCGGAGTCA CATTTTCGTG TCAGGAAGGA TACCAGTTGA TGGGAGTAAC CAAAATCACA 5460 TGTTTGGAGT CTGGAGAATG GAATCATCTA ATACCATATT GTAAAGCTGT TTCATGTGGT 5520 AAACCGGCTA TTCCAGAAAA TGGTTGCATT GAGGAGTTAG CATTTACTTT TGGCAGCAAA 5580 GTGACATATA GGTGTAATAA AGGATATACT CTGGCCGGTG ATAAAGAATC ATCCTGTCTT 5640 GCTAACAGTT CTTGGAGTCA TTCCCCTCCT GTGTGTGAAC CAGTGAAGTG TTCTAGTCCG 5700 GAAAATATAA ATAATGGAAA ATATATTTTG AGTGGGCTTA CCTACCTTTC TACTGCATCA 5760 TATTCATGCG ATACAGGATA CAGCTTACAG GGCCCTTCCA TTATTGAATG CACGGCTTCT 5820 GGCATCTGGG ACAGAGCGCC ACCTGCCTGT CACCTCGTCT TCTGTGGAGA ACCACCTGCC 5880 ATCAAAGATG CTGTCATTAC GGGGAATAAC TTCACTTTCA GGAACACCGT CACTTACACT 5940 TGCAAAGAAG GCTATACTCT TGCTGGTCTT GACACCATTG AATGCCTGGC CGACGGCAAG 6000 TGGAGTAGAA GTGACCAGCA GTGCCTGGCT GTCTCCTGTG ATGAGCCACC CATTGTGGAC 6060 CACGCCTCTC CAGAGACTGC CCATCGGCTC TTTGGAGACA TTGCATTCTA CTACTGCTCT 6120 GATGGTTACA GCCTAGCAGA CAATTCCCAG CTTCTCTGCA ATGCCCAGGG CAAGTGGGTA 6180 CCCCCAGAAG GTCAAGACAT GCCCCGTTGT ATAGCTCATT TCTGTGAAAA ACCTCCATCG 6240 GTTTCCTATA GCATCTTGGA ATCTGTGAGC AAAGCAAAAT TTGCAGCTGG CTCAGTTGTG 6300 AGCTTTAAAT GCATGGAAGG CTTTGTACTG AACACCTCAG CAAAGATTGA ATGTATGAGA 6360 GGTGGGCAGT GGAACCCTTC CCCCATGTCC ATCCAGTGCA TCCCTGTGCG GTGTGGAGAG 6420 CCACCAAGCA TCATGAATGG CTATGCAAGT GGATCAAACT ACAGTTTTGG AGCCATGGTG 6480 GCTTACAGCT GCAACAAGGG GTTCTACATC AAAGGGGAAA AGAAGAGCAC CTGCGAAGCC 6540 ACAGGGCAGT GGAGTAGTCC TATACCGACG TGCCACCCGG TATCTTGTGG TGAACCACCT 6600 AAGGTTGAGA ATGGCTTTCT GGAGCATACA ACTGGCAGGA TCTTTGAGAG TGAAGTGAGG 6660 TATCAGTGTA ACCCGGGCTA TAAGTCAGTC GGAAGTCCTG TATTTGTCTG CCAAGCCAAT 6720 CGCCACTGGC ACAGTGAATC CCCTCTGATG TGTGTTCCTC TCGACTGTGG AAAACCTCCC 6780 CCGATCCAGA ATGGCTTCAT GAAAGGAGAA AACTTTGAAG TAGGGTCCAA GGTTCAGTTT 6840 TTCTGTAATG AGGGTTATGA GCTTGTTGGT GACAGTTCTT GGACATGTCA GAAATCTGGC 6900 AAATGGAATA AGAAGTCAAA TCCAAAGTGC ATGCCTGCCA AGTGCCCAGA GCCGCCCCTC 6960 TTGGAAAACC AGCTAGTATT AAAGGAGTTG ACCACCGAGG TAGGAGTTGT GACATTTTCC 7020 TGTAAAGAAG GGCATGTCCT GCAAβGCCCC TCTGTCCTGA AATGCTTGCC ATCCCAGCAA 7080 TGGAATGACT CTTTCCCTGT TTGTAAGATT GTTCTTTGTA CCCCACCTCC CCTAATTTCC 7140 TTTGGTGTCC CCATTCCTTC TTCTGCTCTT CATTTTGGAA GTACTGTCAA GTATTCTTGT 7200 GTAGGTGGGT TTTTCCTAAG AGGAAATTCT ACCACCCTCT GCCAACCTGA TGGCACCTGG 7260 AGCTCTCCAC TGCCAGAATG TGTTCCAGTA GAATGTCCCC AACCTGAGGA AATCCCCAAT 7320 GGAATCATTG ATGTGCAAGG CCTTGCCTAT CTCAGCACAG CTCTCTATAC CTGCAAGCCA 7380 GGCTTTGAAT TGGTGGGAAA TACTACCACC CTTTGTGGAG AAAATGGTCA CTGGCTTGGA 7440 GGAAAACCAA CATGTAAAGC CATTGAGTGC CTGAAACCCA AGGAGATTTT GAATGGCAAA 7500 TTCTCTTACA CGGACCTACA CTATGGACAG ACCGTTACCT ACTCTTGCAA CCGAGGCTTT 7560 CGGCTCGAAG GTCCCAGTGC CTTGACCTGT TTAGAGACAG GTGATTGGGA TGTAGATGCC 7620 CCATCTTGCA ATGCCATCCA CTGTGATTCC CCACAACCCA TTGAAAATGG TTTTGTAGAA 7680 GGTGCAGATT ACAGCTATGG TGCCATAATC ATCTACAGTT GCTTCCCTGG GTTTCAGGTG 7740 GCTGGTCATG CCATGCAGAC CTGTGAAGAG TCAGGATGGT CAAGTTCCAT CCCAACATGT 7800 ATGCCAATAG ACTGTGGCCT CCCTCCTCAT ATAGATTTTG GAGACTGTAC TAAACTCAAA 7860 GATGACCAGG GATATTTTGA GCAAGAAGAC GACATGATGG AAGTTCCATA TGTGACTCCT 7920
CACCCTCCTT ATCATTTGGG AGCAGTGGCT AAAACCTGGG AAAATACAAA GGAGTCTCCT 7980
GCTACACATT CATCAAACTT TCTGTATGGT ACCATGGTTT CATACACCTG TAATCCAGGA 8040
TATGAACTTC TGGGGAACCC TGTGCTGATC TGCCAGGAAG ATGGAACTTG GAATGGCAGT 8100
GCACCATCCT GCATTTCAAT TGAATGTGAC TTGCCTACTG CTCCTGAAAA TGGCTTTTTG 8160
CGTTTTACAG AGACTAGCAT GGGAAGTGCT GTGCAGTATA GCTGTAAACC TGGACACATT 8220
CTAGCAGGCT CTGACTTAAG GCTTTGTCTA GAGAATAGAA AGTGGAGTGG TGCCTCCCCA 8280
CGCTGTGAAG CCATTTCATG CAAAAAGCCA AATCCAGTCA TGAATGGATC CATCAAAGGA 8340
AGCAAGTACA CATACCTGAG CACGTTGTAC TATGAGTGTG ACCCCGGATA TGTGCTGAAT 8400
GGCACTGAGA GGAGAACATG CCAGGATGAC AAAAACTGGG ATGAGGATGA GCCCATTTGC 8460
ATTCCTGTGG ACTGCAGTTC ACCCCCAGTC TCAGCCAATG GCCAGGTGAG AGGAGACGAG 8520
TACACATTCC AAAAAGAGAT TGAATACACT TGCAATGAAG GGTTCTTGCT TGAGGGAGCC 8580
AGGAGTCGGG TTTGTCTTGC CAATGGAAGT TGGAGTGGAG CCACTCCCGA CTGTGTGCCT 8640
GTCAGATGTG CCACCCCGCC ACAACTGGCC AATGGGGTGA CGGAAGGCCT GGACTATGGC 8700
TTCATGAAGG AAGTAACATT CCACTGTCAC GAGGGCTACA TCTTGCACGG TGCTCCAAAA 8760
CTCACCTGTC AGTCAGATGG CAACTGGGAT GCAGAGATTC CTCTCTGTAA ACCAGTCAAC 8820
TGTGGACCTC CTGAAGATCT TGCCCATGGT TTCCCTAATG GTTTTTCCTT TATTCATGGG 8880
GGCCATATAC AGTATCAGTG CTTTCCTGGT TATAAGCTCC ATGGAAATTC ATCAAGAAGG 8940
TGCCTCTCCA ATGGCTCCTG GAGTGGCAGC TCACCTTGGT GCCTGCCTTG CAGATGTTCC 9000
ACACCAGTAA TTGAATATGG AACTGTCAAT GGGACAGATT TTGACTGTGG AAAGGCAGCC 9060
CGGATTCAGT GCTTCAAAGG CTTCAAGCTC CTAGGACTTT CTGAAATCAC CTGTGAAGCC 9120
GATGGCCAGT GGAGCTCTGG GTTCCCCCAC TGTGAACACA CTTCTTGTGG TTCTCTTCCA 9180
ATGATACCAA ATGCGTTCAT CAGTGAGACC AGCTCTTGGA AGGAAAATGT GATAACTTAC 9240
AGCTGCAGGT CTGGATATGT CATACAAGGC AGTTCAGATC TGATTTGTAC AGAGAAAGGG 9300
GTATGGAGCC AGCCTTATCC AGTCTGTGAG CCCTTGTCCT GTGGGTCCCC ACCGTCTGTC 9360
GCCAATGCAG TGGCAACTGG AGAGGCACAC ACCTATGAAA GTGAAGTGAA ACTCAGATGT 9420
CTGGAAGGTT ATACGATGGA TACAGATACA GATACATTCA CCTGTCAGAA AGATGGTCGC 9480
TGGTTCCCTG AGAGAATCTC CTGCAGTCCT AAAAAATGTC CTCTCCCGGA AAACATAACA 9540
CATATACTTG TACATGGGGA CGATTTCAGT GTGAATAGGC AAGTTTCTGT GTCATGTGCA 9600
GAAGGGTATA CCTTTGAGGG AGTTAACATA TCAGTATGTC AGCTTGATGG AACCTGGGAG 9660
CCACCATTCT CCGATGAATC TTGCAGTCCA GTTTCTTGTG GGAAACCTGA AACTCCAGAA 9720
CATGGATTTG TGGTTβGCAG TAAATACACC TTTGAAAGCA CAATTATTTA TCAGTGTGAG 9780
CCTGGCTATG AACTAGAGGG GAACAGGGAA CGTGTCTGCC AGGAGAACAG ACAGTGGAGT 9840
GGAGGGGTGG CAATATGCAA AGAGACCAGG TGTGAAACTC CACTTGAATT TCTCAATGGG 9900
AAAGCTGACA TTGAAAACAG GACGACTGGA CCCAACGTGG TATATTCCTG CAACAGAGGC 9960
TACAGTCTTG AAGGGCCATC TGAGGCACAC TGCACAGAAA ATGGAACCTG GAGCCACCCA 10020
GTCCCTCTCT GCAAACCAAA TCCATGCCCT GTTCCTTTTG TGATTCCCGA GAATGCTCTG 10080
CTGTCTGAAA AGGAGTTTTA TGTTGATCAG AATGTGTCCA TCAAATGTAG GGAAGGTTTT 10140
CTGCTGCAGG GCCACGGCAT CATTACCTGC AACCCCGACG AGACGTGGAC ACAGACAAGC 10200
GCCAAATGTG AAAAAATCTC ATGTGGTCCA CCAGCTCACG TAGAAAATGC AATTGCTCGA 10260
GGCGTACATT ATCAATATGG AGACATGATC ACCTACTCAT GTTACAGTGG ATACATGTTG 10320
GAGGGTTTCC TGAGGAGTGT TTGTTTAGAA AATGGAACAT GGACATCACC TCCTATTTGC 10380
AGAGCTGTCT GTCGATTTCC ATGTCAGAAT GGGGGCATCT GCCAACGCCC AAATGCTTGT 10440
TCCTGTCCAG AGGGCTGGAT GGGGCGCCTC TGTGAAGAAC CAATCTGCAT TCTTCCCTGT 10500
CTGAACGGAG GTCGCTGTGT GGCCCCTTAC CAGTGTGACT GCCCGCCTGG CTGGACGGGG 10560
TCTCGCTGTC ATACAGCTGT TTGCCAGTCT CCCTGCTTAA ATGGTGGAAA ATGTGTAAGA 10620
CCAAACCGAT GTCACTGTCT TTCTTCTTGG ACGGGACATA ACTGTTCCAG GTAA
Seq ID NO : 430 Protein sequence
Protein Accession ft : FGENESH predicted
I 11 21 31 41 51
I I II t 1 i 1 l 1 l 1
MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP APGDEAAGSR 60
VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR SELMFVRKLL SDFPWPTAT 120
RVAIVTFSSK NYWPRVDYI STRRARQHKC ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL 180
LHARENSTKV VFLITDGYSN GGDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE 240
EHCYLLHSFE EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT 300
GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS PPGSTSPEDC 360
VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA ACGVRCHPGF DLVGSSIILC 420
LPNGLWSGSE SYCRVRTCPH LRQPKHGHIS CSTREMLYKT TCLVACDEGY RLEGSDKLTC 480
QGNSQWDGPE PRCVERHCST FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE 540
MLRCTTSβKW NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK 600
VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI DWCRSPPPVQ 660
VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET IVQYTATDPS GNNRTCDIHI 720
VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY 780
TTEWPDCAKK RFANHGFKSF EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI 840
DCRLEENLTK KYCLEYNYDY ENGFAIGPGG WGAANRLDYS YDDFIϋTVQE TATSIGNAKS 900
SRIKRSAPLS DYKIKLIFNI TASVPLPDER NDTLEWENQQ RLLQTLETIT NKLKRTLNKD 960
PMYSFQLASE ILIADSNSLE TKKASPFCRP GSVLRGRMCV NCPLGTYYNL EHFTCESCRI 1020
GSYQDEEGQL ECKLCPSGMY TEYIHSRNIS DCKAQCKQGT YSYSGLETCE SCPLGTYQPK 1080
FGSRSCLSCP ENTSTVKRGA VNISACGVPC PEGKFSRSGL MPCHPCPRDY YQPNAGKAFC 1140
LACPFYGTTP FAGSRSITEC STSVLNITIF GGFGHLELLN CPSEVFHECF FNPCHNSGTC 1200
QQLGRGYVCL CPLGYTGLKC ETDIDECSPL PCLNNGVCKD LVGEFICECP SGYTGQRCEE 1260
NINECSSSPC LNKGICVDGV AGYRCTCVKG FVGLHCETEV NECQSNPCLN NAVCEDQVGG 1320
FLCKCPPGFL GTRCGKNVDE CLSQPCKNGA TCKDGANSFR CLCAAGFTGS HCELNINECQ 1380
SNPCRNQATC VDELNSYSCK CQPGFSGKRC ETEQSTGFNL DFEVSGIYGY VMLDGMLPSL 1440
HALTCTFWMK SSDDMNYGTP ISYAVDNGSD NTLLLTDYNG WVLYVNGREK ITNCPSVNDG 1500
RWHHIAITWT SANGIWKVYI DGKLSDGGAG LSVGLPIPGG GALVLGQEQD KKGEGFSPAE 1560
SFVGSISQLN LWDYVLSPQQ VKSLATSCPE ELSKGNVLAW PDFLSGIVGK VKIDSKSIFC 1620
SDCPRLGGSV PHLRTASEDL KPGSKVNLFC DPGFQLVGNP VQYCLNQGQW TQPLPHCERI 1680
SCGVPPPLEN GFHSADDFYA GSTVTYQCNN GYYLLGDSRM FCTDNGSWNG VSPSCLDVDE 1740
CAVGSDCSEH ASCLNVDGSY ICSCVPPYTG DGKNCAEPIK CKAPGNPENG HSSGEIYTVG 1800
AGVTFSCQEG YQLMGVTKIT CLESGEWNHL IPYCKAVSCG KPAIPENGCI EELAFTFGSK 1860 VTYRCNKGYT LAGDKESSCL ANSSWSHSPP VCEPVKCSSP ENINNGKYIL SGLTYLSTAS 1920 YSCDTGYSLQ GPSIIECTAS GIWDRAPPAC HLVFCGEPPA IKDAVITGNN FTFRNTVTYT 1980 CKEGYTLAGL DTIECLADGK WSRSDQQCLA VSCDEPPIVD HASPETAHRL FGDIAFYYCS 2040 DGYSLADNSQ LLCNAQGKWV PPEGQDMPRC lAHFCEKPPS VSYSILESVS KAKFAAGSW 2100 SFKCMEGFVL NTSAKIECMR GGQWNPSPMS IQCIPVRCGE PPSIMNGYAS GSNYSFGAMV 2160 AYSCNKGFYI KGEKKSTCEA TGQWSSPIPT CHPVSCGEPP KVENGFLEHT TGRIFESEVR 2220 YQCNPGYKSV GSPVFVCQAN RHWHSESPLM CVPLDCGKPP PIQNGFMKGE NFEVGSKVQF 2280 FCNEGYELVG DSSWTCQKSG KWNKKSNPKC MPAKCPEPPL LENQLVLKEL TTEVGWTFS 2340 CKEGHVLQGP SVLKCLPSQQ WNDSFPVCKI VLCTPPPLIS FGVPIPSSAL HFGSTVKYSC 2400 0 VGGFFLRGNS TTLCQPDGTW SSPLPECVPV ECPQPEEIPN GIIDVQGLAY LSTALYTCKP 2460 GFELVGNTTT LCGENGHWLG GKPTCKAIEC LKPKEILNGK FSYTDLHYGQ TVTYSCNRGF 2520 RLEGPSALTC LETGDWDVDA PSCNAIHCDS PQPIENGFVE GADYSYGAII IYSCFPGFQV 2580 AGHAMQTCEE SGWSSSIPTC MPIDCGLPPH IDFGDCTKLK DDQGYFEQED DMMEVPYVTP 2640 HPPYHLGAVA KTWENTKESP ATHSSNFLYG TMVSYTCNPG YELLGNPVLI CQEDGTWNGS 2700 5 APSCISIECD LPTAPENGFL RFTETSMGSA VQYSCKPGHI LAGSDLRLCL ENRKWSGASP 2760 RCEAISCKKP NPVMNGSIKG SNYTYLSTLY YECDPGYVLN GTERRTCQDD KNWDEDEPIC 2820 IPVDCSSPPV SANGQVRGDE YTFQKEIEYT CNEGFLLEGA RSRVCLANGS WSGATPDCVP 2880 VRCATPPQLA NGVTEGLDYG FMKEVTFHCH EGYILHGAPK LTCQSDGNWD AEIPLCKPVN 2940 CGPPEDLAHG FPNGFSFIHG GHIQYQCFPG YKLHGNSSRR CLSNGSWSGS SPSCLPCRCS 3000 0 TPVIEYGTVN GTDFDCGKAA RIQCFKGFKL LGLSEITCEA DGQWSSGFPH CEHTSCGSLP 3060 MIPNAFISET SSWKENVITY SCRSGYVIQG SSDLICTEKG VWSQPYPVCE PLSCGSPPSV 3120 ANAVATGEAH TYESEVKLRC LEGYTMDTDT DTFTCQKDGR WFPERISCSP KKCPLPENIT 3180 HILVHGDDFS VNRQVSVSCA EGYTFEGVNI SVCQLDGTWE PPFSDESCSP VΞCGKPESPE 3240 HGFWGSKYT FESTII QCE PGYELEGNRE RVCQENRQWS GGVAICKETR CETPLEFLNG 3300 5 KADIENRTTG PNWYSCNRG YSLEGPSEAH CTENGTWSHP VPLCKPNPCP VPFVIPENAL 3360 LSEKEFYVDQ NVSIKCREGF LLQGHGIITC NPDETWTQTS AKCEKISCGP PAHVENAIAR 3420 GVHYQYGDMI TYSCYSGYML EGFLRSVCLE NGTWTSPPIC RAVCRFPCQN GGICQRPNAC 3480 SCPEGWMGRL CEEPICILPC LNGGRCVAPY QCDCPPGWTG SRCHTAVCQS PCLNGGKCVR 3540 PNRCHCLSSW TGHNCSR 0
Seq ID NO: 431 DNA sequence
Nucleic Acid Accession ft: FGENESH predicted
Coding sequence: 1..390 5 11 21 31 41 51
I I I I I
ATGAGGTTCA GTGTCTCAGG CATGAGGACC GACTACCCCA GGAGTGTGCT GGCTCCTGCT 60 TATGTGTCAG TCTGTCTCCT CCTCTTGTGT CCAAGGGAAG TCATCGCTCC CGCTGGCTCA 120 GAACCATGGC TGTGCCAGCC GGCACCCAGG TGTGGAGACA AβATCTACAA CCCCTTGGAG 180 0 CAGTGCTGTT ACAATGACGC CATCGTGTCC CTGAGCGAGA CCCGCCAATG TGGTCCCCCC 240 TGCACCTTCT GGCCCTGCTT TGAGCTCTGC TGTCTTGATT CCTTTGGCCT CACAAACGAT 300 TTTGTTGTGA AGCTGAAGGT TCAGGGTGTG AATTCCCAGT GCCACTCATC TCCCATCTCC 360 AGTAAATGTG AAAGAGGCCG GATATGTTAG
45 Seq ID NO: 432 Protein sequence Protein Accesεion ft: FGENESH predicted
1 11 21 31 41 51
_.n I I I I I I
_>U MRFSVSGMRT DYPRSVLAPA YVSVCLLLLC PREVIAPAGS EPWLCQPAPR CGDKIYNPLE 60
QCCYNDAIVS LSETRQCGPP CTFWPCFELC CLDSFGLTND FWKLKVQGV NSQCHSSPIS 120 SKCERGRIC
Seq ID NO: 433 DNA sequence 55 Nucleic Acid Accession #: NM_007231.1 Coding sequence: 89..2017
11 21 31 41 51
60 I I I I I
TAGGAACAGG GGAGAGTGCA CCTGCTACCA GTCAAGCTCA GCCAGACTGC AAGAGGAGGC 60 GAGGCGGAGC CAGCCGAGGG AGTGAACCAT GGACAAGTTG AAATGCCCGA GTTTCTTCAA 120 GTGCAGGGAG AAGGAGAAAG TGTCGGCTTC ATCAGAGAAT TTCCATGTTG GTGAAAATGA 180 TGAGAATCAG GACCGTGGTA ACTGGTCCAA AAAATCGGAT TATCTTCTAT CTATGATTGG 240 ATACGCAGTG GGATTAGGAA ATGTGTGGAG ATTTCCATAT CTGACCTACA GCAATGGTGG 300
65 AGGCGCCTTC TTGATACCTT ATGCAATTAT GTTAGCATTG GCTGGTTTAC CTTTGTTCTT 360 TCTGGAGTGT TCACTGGGAC AATTTGCTAG CTTAGGTCCA GTTTCAGTTT GGAGGATTCT 420 TCCATTGTTT CAAGGTGTGG GAATTACAAT GGTCCTGATC TCCATTTTTG TGACAATCTA 480 TTACAATGTC ATAATTGCCT ATAGTCTTTA CTACATGTTT GCTTCTTTTC AAAGTGAACT 540 ACCATGGAAA AATTGTTCTT CGTGGTCAGA TAAAAACTGT AGGAGATCAC CAATAGTAAC 600
70 TCACTGTAAT GTGAGTACAG TGAATAAAGG AATACAAGAG ATCATCCAAA TGAATAAAAG 660 CTGGGTAGAC ATCAACAATT TTACCTGCAT CAACGGCAGT GAAATTTATC AGCCAGGGCA 720 GCTTCCCAGT GAACAATATT GGAATAAAGT GGCGCTCCAA CGGTCAAGTG GAATGAATGA 780 GACTGGAGTA ATTGTTTGGT ATTTAGCACT TTGTCTTCTT CTGGCTTGGC TCATAGTTGG 840 AGCAGCACTA TTTAAAGGAA TCAAATCGTC TGGCAAGGTG GTATATTTTA CAGCTCTTTT 900
75 CCCCTATGTG GTCCTACTCA TCCTGTTAGT ACGAGGTGCA ACTCTGGAGG GTGCTTCAAA 960 AGGCATTTCA TACTATATTG GAGCCCAGTC AAATTTTACA AAACTTAAGG AAGCTGAGGT 1020 ATGGAAAGAT GCTGCCACTC AGATATTTTA CTCCCTTTCA GTGGCTTGGG GTGGCTTAGT 1080 TGCTCTATCA TCTTACAATA AGTTCAAAAA CAACTGCTTC TCTGATGCCA TTGTGGTTTG 1140 TTTGACAAAC TGTCTCACTA GCGTGTTTGC TGGATTTGCT ATTTTTTCTA TATTGGGACA 1200
80 CATGGCCCAT ATATCTGGAA AGGAAGTTTC TCAAGTTGTA AAATCAGGTT TTGATTTGGC 1260 ATTCATTGCC TATCCAGAGG CTCTAGCCCA ACTCCCAGGT GGTCCATTTT GGTCCATATT 1320 ATTTTTTTTC ATGCTTTTAA CTTTGGGTCT CGATTCTCAG TTTGCTTCGA TTGAAACGAT 1380 CACAACAACA ATTCAAGATT TATTTCCCAA AGTGATGAAG AAAATGAGGG TTCCCATAAC 1440 TTTGGGCTGC TGCTTGGTTT TGTTTCTCCT TGGTCTCGTC TGTGTGACTC AGGCTGGAAT 1500 TTACTGGGTT CATCTGATTG ACCACTTCTG TGCTGGATGG GGCATTTTAA TTGCAGCTAT 1560 ACTGGAGCTA GTTGGAATCA TCTGGATTTA TGGAGGGAAC AGATTCATTG . AGGATACAGA 1620 AATGATGATT GGAGCAAAβA GGTGGATATT CTGGCTATGG TGGAGAGCTT GCTGGTTTGT 1680 AATTACGCCT ATCCTTTTGA TTGCAATATT TATCTGGTCA TTGGTGCAAT TTCATAGACC 1740 TAATTATGGC GCAATTCCAT ACCCTGACTG GGGAGTTGCT TTAGGCTGGT GTATGATTGT 1800 TTTCTGCATT ATTTGGATAC CAATTATGGC TATCATAAAA ATAATTCAGG CTAAAGGAAA 1860 CATCTTTCAA CGCCTTATAA GTTGCTGCAG ACCAGCTTCT AACTGGGGTC CATACCTGGA 1920 ACAACATCGT GGGGAAAGAT ATAAAGACAT GGTAGATCCT AAAAAAGAGG CTGACCATGA 1980 AATACCTACT GTTAGTGGCA GCAGAAAACC GGAATGAGAT CTCATTGAAA AAAATATATG 2040 ATTGTATAAT GTGATTTTTT TTAGAATAGG GGGAACCTTA TTTATTTGTG TGTTAACTGA 2100 ATAGGAAAAT GTACATACTA TGTTCATGAT AGTGTGATTT TTTTCACATT TAAGCAGGAA 2160 TGCAATATAA AAATGTGAAT CTCTTAATTC TCAGCCATGT GCTTATTATA TTTCTTTTTA 2220 GATTGTCTAT CTGTATAACA CACACACACA CACCTAAGAG TCTCTATTTC ACAATTATAT 2280 TTTTGTAAAT AGTATATGCA TTTTTAATAC ATTGGAGGCT TTATTTTGAA CTAATTTCTT 2340 AGAGAATAGT TATATTTTCT ATTACACAAG TTTAAAAATA TTATTAACTT GTATTTTCTT 2400 AATATACAAT CTATCTTTTC CACAAATATG AGTGGGAAAT AAATCAGCAC ATTTGAAAGA 2460 AAGTGTTAAA ACTGAAGGCC TCACTTAATT AGAAACGTGA TAAATATATG GACAAATGGA 2520 CTATACATAC TATAAGAGGA CTGTAGTTTA ATACTTTTTA CCCAAATATG TTTAAAAACA 2580 TCGTGCATTT GTTACAGCTC ATGTTTTCTA TATGAACTTA GTCATTAATG TTCTTTATAA 2640 AAAGTGAAAT AAGATGGAAA AATTAGGATC CTACAGCCAG TACGTGATAA ATCTAGAAAA 2700 TTGAGTTTTG AGTACCTCTT TTCCCATATA CAATCTTCCT TCCTTAGGTA ATTTGGAAGA 2760 AAACTATGAC CCATTTAATT TCTATTGTGT TTCACCAAAT TCAGTGTTGT TCATTATACC 2820 TCTCTGAAAT ATAGGTTTAA TTTCAAATAG AATATGGACT TAAATGTTAA TGAGAAACTG 2880 GCTTTAATCA ATTCTAGCAT TTTATTACTG TAATACAGGG CTGATAGAGT GATTTTGTCT 2940 TATATGAGTC AGTTACTACT TACAGGTGAT AACTTGCATA CTATTGGAAG ATAAAGTTGT 3000 CAAACTTGTC AAGAATGAGA AAAGCCAAAT TAGAAAATCC TATGTCCTAG TTTCCTTACC 3060 AAGGATAATT AAATATATCA CTAAGAGCTT TATATATTGA TTATATATTG TTGACAACTG 3120 GTTTAAGCAT CATAGCCTAT GATGATAAAC ACTGCCTATA TATGTAAATA GCTTTTCATC 3180 AATTCTTAAA TTTCTTAACC TAGGCTTCAG GGAGCATATG AAACCAAAAT TATATGGAAC 3240 ATTTTCTGTG TGTACATGTA CATGCATTTT TCTAGGGAGA GAGTCCGTAG GTTTATCAGA 3300 ATATCAAGGA AAACTGTGAC CCAAAGAAGT TTAAGAATCA CATACAGTGC TGCTGGCTTT 3360 TTGTGCTTGG CAAATGAGTG ACAATAGAAG AAATAATTTT TCTTACACAT TTTAAAACGT 3420 TTTCTCTTCC TTGTGATTGA AGATGAAAGG AGTAAGAAAT TAAGGCATTT GTTTAATTTA 3480 TACTGGTAAC TTATTTAGGG GGGAGGGGAC ATGAAGGTAG GTAAATAGGT AGGCCTCTAA 3540 TTGAACCACC TCTCTAAGTT ATGTACGTAT ATATAAGCTG AAATTGTGTT TGACATTCTG 3600 AGGGTTTTCT TTTTCTTTTT CCTTTTTTTT TTTTTTTGGT GGGGGGCTGG GGGTCAGAGT 3660 CTTGTTCTGT TGCCTGGGCT GGAGTGCAGT GGCATGATCT CAGCTCACTG CAACCTCTGC 3720 CTTCTGGATT CAAGTGATTC TCCTGCCTCA GCCTCTTGAG TAGCTGGGAC TACAGGTGCC 3780 CGCCACCACA CCAGCTAATT TTTGTATTTT TAGTAGAGGC GAAGTTTCCC CATGTTGGCC 3840 AGGCTGGTCT TGAACTCCCG ACCTCAAGTG ATCTGTCTAC CTCGGCCTCC TAAAGTGCTG 3900 AGATTACAGG TGTGAGCCAC CGTGCCCGGC CCATTCTAAG GGTTTTCTTT GAAGACAGGT 3960 CAAATGCTGT TAGTAAGTTT CAGGAGATTG TTAATTCCTC AGTTATACCA GATTTTATAA 4020 AATATTTGAG AATAGATGGC TAACAAGAGG TTAGAAATAC TTTTCCTTAA TTTTAATCCA 4080 CAGTATGTTA CATGCATTCT ACCACTACAT TTTGGTGCTA TTTAAGGTGT GCAATTTTCT 4140 ATAGGTGACT TTTGCAATTC AGGGAAGATT TGGGCATATT AAATGAAAGA . ATATCTAATT 4200 GGGGGAGGTG TGAAGGGAAA GAAATTCTTT TCAAAAGCTG ACCACAAAGA . GTAGTTAAAA 4260 GTTTTTGTCA CTATCTTCAC AAGTGTGTAA AGCACAGATT TCAACAGAGT GCTTGGCATA 4320 TTGTAGGGTG CTCAATGGTG GTTTTTATTA TTATTACTCA GATTCCACAG '■ TGGCAAGAAA 4380 CATCATTCTA CATAATGGAA AACATTTACA TCAAATCCCA CTTACTTTAA . TGCGAACTTG 4440 GAGATAATTT ATGGTATTGT ATTGTAAACC ATTAATGAAA ACTTTTTCAC 1 AGTTGAGTGA 4500 AATTAAAATC ACTATATCTC
Seq ID NO: 434 Protein sequence Protein Accession ft: NP 009162.1
11 21 31 41 51
MDKLKCPSFF KCREKEKVSA SSENFHVGEN DENQDRGNWS KKSDYLLSMI GYAVGLGNVW 60 RFPYLTYSNG GGAFLIPYAI MLALAGLPLF FLECSLGQFA SLGPVSVWRI LPLFQGVGIT 120 MVLISIFVTI YYNVIIAYSL YYMFASFQSE LPWKNCSSWS DKNCSRSPIV THCNVSTVNK 180 GIQEIIQMNK SWVDINNFTC INGSEIYQPG QLPSEQYWNK VALQRSSGMN ETGVIVWYLA 240 LCLLLAWLIV GAALFKGIKS SGKWYFTAL FPYWLLILL VRGATLEGAS KGISYYIGAQ 300 SNFTKLKEAE VWKDAATQIF YSLSVAWGGL VALSSYNKFK NNCFSDAIW CLTNCLTSVF 360 AGFAIFSILG HMAHISGKEV SQWKSGFDL AFIAYPEALA QLPGGPFWSI LFFFMLLTLG 420 LDSQFASIET ITTTIQDLFP KVMKKMRVPI TLGCCLVLFL LGLVCVTQAG IYWVHLIDHF 480 CAGWGILIAA ILELVGIIWI YGGNRFIEDT EMMIGAKRWI FWLWWRACWF VITPILLIAI 540 FIWSLVQFHR PNYGAIPYPD WGVALGWCMI VFCIIWIPIM AIIKIIQAKG NIFQRLISCC 600 RPASNWGPYL EQHRGERYKD MVDPKKEADH EIPTVSGSRK PE
Seq ID NO: 435 DNA sequence Nucleic Acid Accession ft: M18728.1 Coding sequence: 51..1085
11 21 31 41 51
I I I I I
GGAGCTCAAG CTCCTCTACA AAGAGGTGGA CAGAGAAGAC AGCAGAGACC ATGGGACCCC 60 CCTCAGCCCC TCCCTGCAGA TTGCATGTCC CCTGGAAGGA GGTCCTGCTC ACAGCCTCAC 120 TTCTAACCTT CTGGAACCCA CCCACCACTG CCAAGCTCAC TATTGAATCC ACGCCATTCA 180 ATGTCGCAGA GβGGAAGGAG GTTCTTCTAC TCGCCCACAA CCTGCCCCAG AATCGTATTG 240 GTTACAGCTG GTACAAAGGC GAAAGAGTGG ATGGCAACAG TCTAATTGTA GGATATGTAA 300 TAGGAACTCA ACAAGCTACC CCAGGGCCCG CATACAGTGG TCGAGAGACA ATATACCCCA 360 ATGCATCCCT GCTGATCCAG AACCTCACCC AGAATGACAC AGGATTCTAT ACCCTACAAG 420 TCATAAAGTC AGATCTTGTG AATGAAGAAG CAACCGGACA GTTCCATGTA TACCCGGAGC 480 TGCCCAAGCC CTCCATCTCC AGCAACAACT CCAACCCCGT GGAGGACAAG GATGCTGTGG 540 CCTTCACCTG TGAACCTGAG GTTCAGAACA CAACCTACCT GTGGTGGGTA AATGGTCAGA 600 GCCTCCCGGT CAGTCCCAGG CTGCAGCTGT CCAATβGCAA CATGACCCTC ACTCTACTCA 660 GCGTCAAAAG GAACGATGCA GGATCCTATG AATGTGAAAT ACAGAACCCA GCGAGTGCCA 720 ACCGCAGTGA CCCAGTCACC CTGAATGTCC TCTATGGCCC AGATGTCCCC ACCATTTCCC 780 CCTCAAAGGC CAATTACCGT CCAGGGGAAA ATCTGAACCT CTCCTGCCAC GCAGCCTCTA 840 ACCCACCTGC ACAGTACTCT TGGTTTATCA ATGGGACGTT CCAGCAATCC ACACAAGAGC 900 TCTTTATCCC CAACATCACT GTGAATAATA GCGGATCCTA TATGTGCCAA GCCCATAACT 960 CAGCCACTGG CCTCAATAGG ACCACAGTCA CGATGATCAC AGTCTCTGGA AGTGCTCCTG 1020 TCCTCTCAGC TGTGGCCACC GTCGGCATCA CGATTGGAGT GCTGGCCAGG GTGGCTCTGA 1080 TATAGCAGCC CTGGTGTATT TTCGATATTT CAGGAAGACT GGCAGATTGG ACCAGACCCT 1140 GAATTCTTCT AGCTCCTCCA ATCCCATTTT ATCCCATGGA ACCACTAAAA ACAAGGTCTG 1200 CTCTGCTCCT GAAGCCCTAT ATGCTGGAGA TGGACAACTC AATGAAAATT TAAAGGGAAA 1260 ACCCTCAGGC CTGAGGTGTG TGCCACTCAG AGACTTCACC TAACTAGAGA CAGTCAAACT 1320 GCAAACCATG GTGAGAAATT GACGACTTCA CACTATGGAC AGCTTTTCCC AAGATGTCAA 1380 AACAAGACTC CTCATCATGA TAAGGCTCTT ACCCCCTTTT AATTTGTCCT TGCTTATGCC 1440 TGCCTCTTTC GCTTGGCAGG ATGATGCTGT CATTAGTATT TCACAAGAAG TAGCTTCAGA 1500 GGGTAACTTA ACAGAGTGTC AGATCTATCT TGTCAATCCC AACGTTTTAC ATAAAATAAG 1560 AGATCCTTTA GTGCACCCAG TGACTGACAT TAGCAGCATC TTTAACACAG CCGTGTGTTC 1620 AAATGTACAG TGGTCCTTTT CAGACTTGGA CTTCTAGACT CACCTGTTCT CACTCCCTGT 1680 TTTAATTCAA CCCAGCCATG CAATGCCAAA TAATAGAATT GCTCCCTACC AGCTGAACAG 1740 GGAGGAGTCT GTGCAGTTTC TGACACTTGT TGTTGAACAT GGCTAAATAC AATGG6TATC 1800 GCTGAGACTA AGTTGTAGAA ATTAACAAAT GTGCTGCTTG CTTAAAATGG CTACACTCAT 1860 CTGACTCATT CTTTATTCTA TTTTAGTTGG TTTGTATCTT GCCTAAGGTG CGTAGTCCAA 1920 CTCTTGGTAT TACCCTCCTA ATAGTCATAC TAGTAGTCAT ACTCCCTGGT GTAGTGTATT 1980 CTCTAAAAGC TTTAAATGTC TGCATGCAGC CAGCCATCAA ATAGTGAATG GTCTCTCTTT 2040 GGCTGGAATT ACAAAACTCA GAGAAATGTG TCATCAGGAG AACATCATAA CCCATGAAGG 2100 ATAAAAGCCC CAAATGGTGG TAACTGATAA TAGCACTAAT GCTTTAAGAT TTGGTCACAC 2160 TCTCACCTAG GTGAGCGCAT TGAGCCAGTG GTGCTAAATG CTACATACTC CAACTGAAAT 2220 GTTAAGGAAG AAGATAGATC CAATTAAAAA AAATTAAAAC CAATTTAAAA AAAAAAAAGA 2280 ACACAGGAGA TTCCAGTCTA CTTGAGTTAG CATAATACAG AAGTCCCCTC TACTTTAACT 2340 TTTACAAAAA AGTAACCTGA ACTAATCTGA TGTTAACCAA TGTATTTATT TCTGTGGTTC 2400 TGTTTCCTTG TTCCAATTTG ACAAAACCCA CTGTTCTTGT ATTGTATTGC CCAGGGGGAG 2460 CTATCACTGT ACTTGTAGAG TGGTGCTGCT TTAATTCATA AATCACAAAT AAAAGCCAAT 2520 TAGCTCTATA ACT
Seq ID NO: 436 Protein sequence Protein Accession ft: AAA59907.1
11 21 31 41 51
I I I I I
MGPPSAPPCR LHVPWKEVLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLAHNLPQ 60 NRIGYSWYKG ERVDGNSLIV GYVIGTQQAT PGPAYSGRET IYPNASLLIQ NVTQNDTGFY 120 TLQVIKSDLV NEEATGQFHV YPELPKPSIS SNNSNPVEDK DAVAFTCEPE VQNTTYLWWV 180 NGQSLPVSPR LQLSNGNMTL TLLSVKRNDA GSYECEIQNP ASANRSDPVT LNVLYGPDVP 240 TISPSKANYR PGENLNLSCH AASNPPAQYS WFINGTFQQS TQELFIPNIT VNNSGSYMCQ 300 AHNSATGLNR TTVTMITVSG SAPVLSAVAT VGITIGVLAR VALI
Seq ID NO: 437 DNA sequence Nucleic Acid Accession ff: M18728.1 Coding sequence: 1355..1657
11 21 31 41 51
I I I I
GGAGCTCAAG CTCCTCTACA AAGAGGTGGA CAGAGAAGAC AGCAGAGACC ATGGGACCCC 60 CCTCAGCCCC TCCCTGCAGA TTGCATGTCC CCTGGAAGGA GGTCCTGCTC ACAGCCTCAC 120 TTCTAACCTT CTGGAACCCA CCCACCACTG CCAAGCTCAC TATTGAATCC ACGCCATTCA 180 ATGTCGCAGA GGGGAAGGAG GTTCTTCTAC TCGCCCACAA CCTGCCCCAG AATCGTATTG 240 GTTACAGCTG GTACAAAGGC GAAAGAGTGG ATGGCAACAG TCTAATTGTA GGATATGTAA 300 TAGGAACTCA ACAAGCTACC CCAGGGCCCG CATACAGTGG TCGAGAGACA ATATACCCCA 360 ATGCATCCCT GCTGATCCAG AACGTCACCC AGAATGACAC AGGATTCTAT ACCCTACAAG 420 TCATAAAGTC AGATCTTGTG AATGAAGAAG CAACCGGACA GTTCCATGTA TACCCGGAGC 480 TGCCCAAGCC CTCCATCTCC AGCAACAACT CCAACCCCGT GGAGGACAAG GATGCTGTGG 540 CCTTCACCTG TGAACCTGAG GTTCAGAACA CAACCTACCT GTGGTGGGTA AATGGTCAGA 600 GCCTCCCGGT CAGTCCCAGG CTGCAGCTGT CCAATGGCAA CATGACCCTC ACTCTACTCA 660 GCGTCAAAAG GAACGATGCA GGATCCTATG AATGTGAAAT ACAGAACCCA GCGAGTGCCA 720 ACCGCAGTGA CCCAGTCACC CTGAATGTCC TCTATGGCCC AGATGTCCCC ACCATTTCCC 780 CCTCAAAGGC CAATTACCGT CCAGGGGAAA ATCTGAACCT CTCCTGCCAC GCAGCCTCTA 840 ACCCACCTGC ACAGTACTCT TGGTTTATCA ATGGGACGTT CCAGCAATCC ACACAAGAGC 900 CTTTATCCC CAACATCACT GTGAATAATA GCGGATCCTA TATGTGCCAA GCCCATAACT 960 CAGCCACTGG CCTCAATAGG ACCACAGTCA CGATGATCAC AGTCTCTGGA AGTGCTCCTG 1020 TCCTCTCAGC TGTGGCCACC GTCGGCATCA CGATTGGAGT GCTGGCCAGG GTGGCTCTGA 1080 TATAGCAGCC CTGGTGTATT TTCGATATTT CAGGAAGACT GGCAGATTGG ACCAGACCCT 1140 GAATTCTTCT AGCTCCTCCA ATCCCATTTT ATCCCATGGA ACCACTAAAA ACAAGGTCTG 1200 CTCTGCTCCT GAAGCCCTAT ATGCTGGAGA TGGACAACTC AATGAAAATT TAAAGGGAAA 1260 ACCCTCAGGC CTGAGGTGTG TGCCACTCAG AGACTTCACC TAACTAGAGA CAGTCAAACT 1320 GCAAACCATG GTGAGAAATT GACGACTTCA CACTATGGAC AGCTTTTCCC AAGATGTCAA 1380 AACAAGACTC CTCATCATGA TAAGGCTCTT ACCCCCTTTT AATTTGTCCT TGCTTATGCC 1440 TGCCTCTTTC GCTTGGCAGG ATGATGCTGT CATTAGTATT TCACAAGAAG TAGCTTCAGA 1500 GGGTAACTTA ACAGAGTGTC AGATCTATCT TGTCAATCCC AACGTTTTAC ATAAAATAAG 1560 AGATCCTTTA GTGCACCCAG TGACTGACAT TAGCAGCATC TTTAACACAG CCGTGTGTTC 1620 AAATGTACAG TGGTCCTTTT CAGAGTTGGA CTTCTAGACT CACCTGTTCT CACTCCCTGT 1680 TTTAATTCAA CCCAGCCATG CAATGCCAAA TAATAGAATT GCTCCCTACC AGCTGAACAG 1740 GGAGGAGTCT GTGCAGTTTC TGACACTTGT TGTTGAACAT GGCTAAATAC AATGGGTATC 1800 GCTGAGACTA AGTTGTAGAA ATTAACAAAT GTGCTGCTTG GTTAAAATGG CTACACTCAT 1860 CTGACTCATT CTTTATTCTA TTTTAGTTGG TTTGTATCTT GCCTAAGGTG CGTAGTCCAA 1920 CTCTTGGTAT TACCCTCCTA ATAGTCATAC TAGTAGTCAT ACTCCCTGGT GTAGTGTATT 1980 CTCTAAAAGC TTTAAATGTC TGCATGCAGC CAGCCATCAA ATAGTGAATG GTCTCTCTTT 2040 GGCTGGAATT ACAAAACTCA GAGAAATGTG TCATCAGGAG AACATCATAA CCCATGAAGG 2100 ATAAAAGCCC CAAATGGTGG TAACTGATAA TAGCACTAAT GCTTTAAGAT TTGGTCACAC 2160 TCTCACCTAG GTGAGCGCAT TGAGCCAGTG GTGCTAAATG CTACATACTC CAACTGAAAT 2220 GTTAAGGAAG AAGATAGATC CAATTAAAAA AAATTAAAAC CAATTTAAAA AAAAAAAAGA 2280 ACACAGGAGA TTCCAGTCTA CTTGAGTTAG CATAATACAG AAGTCCCCTC TACTTTAACT 2340 TTTACAAAAA AGTAACCTGA ACTAATCTGA TGTTAACCAA TCTATTTATT TCTGTGGTTC 2400 TGTTTCCTTG TTCCAATTTG ACAAAACCCA CTGTTCTTGT ATTGTATTGC CCAGGGGGAG 2460 CTATCACTGT ACTTGTAGAG TGGTGCTGCT TTAATTCATA AATCACAAAT AAAAGCCAAT 2520 TAGCTCTATA ACT
Seq ID NO: 438 Protein sequence Protein Acceεεion #: AAA59908.1
1 11 21 31 41 51
I I I I I I
MDSFSQDVKT RLLIMIRLLP PFNLSLLMPA SFAWQDDAVI SISQEVASEG NLTECQIYLV
NPNVLHKIRD PLVHPVTDIS SIFNTAVCSN VQWSFSELDF
Seq ID NO : 439 DNA sequence Nucleic Acid Accession ft : M18728.1 Coding sequence : 2370. .2501
11 21 31 51
GGAGCTCAAG CTCCTCTACA AAGAGGTGGA CAGAGAAGAC AGCAGAGACC ATGGGACCCC 60
CCTCAGCCCC TCCCTGCAGA TTGCATGTCC CCTGGAAGGA GGTCCTGCTC ACAGCCTCAC 120
TTCTAACCTT CTGGAACCCA CCCACCACTG CCAAGCTCAC TATTGAATCC ACGCCATTCA 180
ATGTCGCAGA GGGGAAGGAG GTTCTTCTAC TCGCCCACAA CCTGCCCCAG AATCGTATTG 240
GTTACAGCTG GTACAAAGGC GAAAGAGTGG ATGGCAACAG TCTAATTGTA GGATATGTAA 300
TAGGAACTCA ACAAGCTACC CCAGGGCCCG CATACAGTGG TCGAGAGACA ATATACCCCA 360
ATGCATCCCT GCTGATCCAG AACGTCACCC AGAATGACAC AGGATTCTAT ACCCTACAAG 420
TCATAAAGTC AGATCTTGTG AATGAAGAAG CAACCGGACA GTTCCATGTA TACCCGGAGC 480
TGCCCAAGCC CTCCATCTCC AGCAACAACT CCAACCCCGT GGAGGACAAG GATGCTGTGG 540
CCTTCACCTG TGAACCTGAG GTTCAGAACA CAACCTACCT GTGGTGGGTA AATGGTCAGA 600
GCCTCCCGGT CAGTCCCAGG CTGCAGCTGT CCAATGGCAA CATGACCCTC ACTCTACTCA 660
GCGTCAAAAG GAACGATGCA GGATCCTATG AATGTGAAAT ACAGAACCCA GCGAGTGCCA 720
ACCGCAGTGA CCCAGTCACC CTGAATGTCC TCTATGGCCC AGATGTCCCC ACCATTTCCC 780
CCTCAAAGGC CAATTACCGT CCAGGGGAAA ATCTGAACCT CTCCTGCCAC GCAGCCTCTA 840
ACCCACCTGC ACAGTACTCT TGGTTTATCA ATGGGACGTT CCAGCAATCC ACACAAGAGC 900
TCTTTATCCC CAACATCACT GTGAATAATA GCGGATCCTA TATGTGCCAA GCCCATAACT 960
CAGCCACTGG CCTCAATAGG ACCACAGTCA CGATGATCAC AGTCTCTGGA AGTGCTCCTG 1020
TCCTCTCAGC TGTGGCCACC GTCGGCATCA CGATTGGAGT GCTGGCCAGG GTGGCTCTGA 1080
TATAGCAGCC CTGGTGTATT TTCGATATTT CAGGAAGACT GGCAGATTGG ACCAGACCCT 1140
GAATTCTTCT AGCTCCTCCA ATCCCATTTT ATCCCATGGA ACCACTAAAA ACAAGGTCTG 1200
CTCTGCTCCT GAAGCCCTAT ATGCTGGAGA TGGACAACTC AATGAAAATT TAAAGGGAAA 1260
ACCCTCAGGC CTGAGGTGTG TGCCACTCAG AGACTTCACC TAACTAGAGA CAGTCAAACT 1320
GCAAACCATG GTGAGAAATT GACGACTTCA CACTATGGAC AGCTTTTCCC AAGATGTCAA 1380
AACAAGACTC CTCATCATGA TAAGGCTCTT ACCCCCTTTT AATTTGTCCT TGCTTATGCC 1440
TGCCTCTTTC GCTTGGCAGG ATGATGCTGT CATTAGTATT TCACAAGAAG TAGCTTCAGA 1500
GGGTAACTTA ACAGAGTGTC AGATCTATCT TGTCAATCCC AACGTTTTAC ATAAAATAAG 1560
AGATCCTTTA GTGCACCCAG TGACTGACAT TAGCAGCATC TTTAACACAG CCGTGTGTTC 1620
AAATGTACAG TGGTCCTTTT CAGACTTGGA CTTCTAGACT CACCTGTTCT CACTCCCTGT 1680
TTTAATTCAA CCCAGCCATG CAATGCCAAA TAATAGAATT GCTCCCTACC AGCTGAACAG 1740
GGAGGAGTCT GTGCAGTTTC TGACACTTGT TGTTGAACAT GGCTAAATAC AATGGGTATC 1800
GCTGAGACTA AGTTGTAGAA ATTAACAAAT GTGCTGCTTG GTTAAAATGG CTACACTCAT 1860
CTGACTCATT CTTTATTCTA TTTTAGTTGG TTTGTATCTT GCCTAAGGTG CGTAGTCCAA 1920
CTCTTGGTAT TACCCTCCTA ATAGTCATAC TAGTAGTCAT ACTCCCTGGT GTAGTGTATT 1980
CTCTAAAAGC TTTAAATGTC TGCATGCAGC CAGCCATCAA ATAGTGAATG GTCTCTCTTT 2040
GGCTGGAATT ACAAAACTCA GAGAAATGTG TCATCAGGAG AACATCATAA CCCATGAAGG 2100
ATAAAAGCCC CAAATGGTGG TAACTGATAA TAGCACTAAT GCTTTAAGAT TTGGTCACAC 2160
TCTCACCTAG GTGAGCGCAT TGAGCCAGTG GTGCTAAATG CTACATACTC CAACTGAAAT 2220
GTTAAGGAAG AAGATAGATC CAATTAAAAA AAATTAAAAC CAATTTAAAA AAAAAAAAGA 2280
ACACAGGAGA TTCCAGTCTA CTTGAGTTAG CATAATACAG AAGTCCCCTC TACTTTAACT 2340
TTTACAAAAA AGTAACCTGA ACTAATCTGA . TGTTAACCAA TGTATTTATT TCTGTGGTTC 2400
TGTTTCCTTG TTCCAATTTG ACAAAACCCA CTGTTCTTGT ATTGTATTGC CCAGGGGGAG 2460
CTATCACTGT ACTTGTAGAG TGGTGCTGCT TTAATTCATA AATCACAAAT AAAAGCCAAT 2520
TAGCTCTATA ACT
Seq ID NO: 440 Protein sequence Protein Acceεsion ff: AAA59909.1 1 11 21 31 41 51 l l l l l
MLTNVFISW LFPCSNLTKP TVLVLYCPGG AITVLVEWCC FNS Seq ID NO: 441 DNA sequence
Nucleic Acid Accession ft: NM_002381.2 Coding sequence: 64..1524
51 AAATCCGAGC CTCGCGTGGG CTCCTGGCCC CCGACGGACA CCACCAGGCC CACGGAGCCC 60
ACCATGCCGC GCCCGGCCCC CGCGCGCCGC CTCCCGGGAC TCCTCCTGCT GCTCTGGCCG 120
CTGCTGCTGC TGCCCTCCGC CGCCCCCGAC CCCGTGGCCC GCCCGGGCTT CCGGAGGCTG 180
GAGACCCGAG GTCCCGGGGG CAGCCCTGGA CGCCGCCCCT CTCCTGCGGC TCCCGACGGC 240
GCGCCCGCTT CCGGGACCAG CGAGCCTGGC CGCGCCCGCG GTGCAGGTGT TTGCAAGAGC 300
AGACCCTTGG ACCTGGTGTT TATCATTGAT AGTTCTCGTA GCGTACGGCC CCTGGAATTC 360
ACCAAAGTGA AAACTTTTGT CTCCCGGATA ATCGACACTC TGGACATTGG GCCAGCCGAC 420
ACGCGGGTGG CAGTGGTGAA CTATGCTAGC ACTGTGAAGA TCGAGTTCCA ACTCCAGGCC 480
TACACAGATA AGCAGTCCCT GAAGCAGGCT GTGGGTCGAA TCACACCCTT CTCAACAGGC 540
ACCATGTCAG GCCTAGCCAT CCAGACAGCA ATGGACGAAG CCTTCACAGT GGAGGCAGGG 600
GCTCGAGAGC CCTCTTCTAA CATCCCTAAG GTGGCCATCA TTGTTACAGA TGGGAGGCCC 660
CAGGACCAGG TGAATGAAGT GGCGGCTCGG GCCCAAGCAT CTGGTATTGA GCTCTATGCT 720
GTGGGCGTGG ACCGGGCAGA CATGGCGTCC CTCAAGATGA TGGCCAGTGA GCCCCTAGAG 780
GAGCATGTTT TCTACGTGGA GACCTATGGG GTCATTGAGA AACTTTCCTC TAGATTCCAG 840
GAAACCTTCT GTGCGCTGGA CCCCTGTGTG CTTGGAACAC ACCAGTGCCA GCACGTCTGC 900
ATCAGTGATG GGGAAGGCAA GCACCACTGT GAGTGTAGCC AAGGATACAC CTTGAATGCC 960
GACAAGAAAA CGTGTTCAGC TCTTGATAGG TGTGCTCTTA ACACCCACGG ATGTGAGCAC 1020
ATCTGTGTGA ATGACAGAAG TGGCTCTTAT CATTGTGAGT GCTATGAAGG TTATACCTTG 1080
AATGAAGACA GGAAAACTTG TTCAGCTCAA GATAAATGTG CTTTGGGTAC CCATGGGTGT 1140
CAGCACATTT GTGTGAATGA CAGAACAGGG TCCCATCATT GTGAATGCTA TGAGGGCTAC 1200
ACTCTGAATG CAGATAAAAA AACATGTTCA GTCCGTGACA AGTGTGCCCT AGGCTCTCAT 1260
GGTTGCCAGC ACATTTGTGT GAGTGATGGG GCCGCATCCT ACCACTGTGA TTGCTATCCT 1320
GGCTACACCT TAAATGAGGA CAAGAAAACA TGTTCAGCCA CTGAGGAAGC ACGAAGACTT 1380
GTTTCCACTG AAGATGCTTG TGGATGTGAA GCTACACTGG CATTCCAGGA CAAGGTCAGC 1440
TCGTATCTTC AAAGACTGAA CACTAAACTT GATGACATTT TGGAGAAGTT GAAAATAAAT 1500
GAATATGGAC AAATACATCG TTAAATTGCT CCAATTTCTC ACCTGAAAAT GTGGACAGCT 1560
TGGTGTACTT AATACTCATG CATTCTTTTG CACACCTGTT ATTGCCAATG TTCCTGCTAA 1620
TAATTTGCCA TTATCTGTAT TAATGCTTGA ATATTACTGG ATAAATTGTA TGAAGATCTT 1680
CTGCAGAATC AGCATGATTT TTCCAAGGAA ATACATATGC AGATACTTAT TAAGAGCAAA 1740
CTTTAGTGTC TCTAAGTTAT GACTGTGAAA TGATTGGTAG GAAATAGAAT GAAAAGTTTA 1800
GTGTTTCTTT ATCTACTAAT TGAGCCATTT AATTTTTAAA TGTTTATATT AGATAACCAT 1860
ATTCACAATG GAAACTTTAG GTCTAGTTTC TTTTGATAGT ATTTATAATA TAAATCAATC 1920
TTATTACTGA GAGTGCAAAT TGTACAAGGT ATTTACACAT ACAACTTCAT ATAACTGAGA 1980
TGAATGTAAT TTTGAACTGT TTAACACTTT TTGTTTTTTG CTTATTTTGT TGGAGTATTA 2040
TTGAAGATGT GATCAATAGA TTGTAATACA CATATCTAAA AATAGTTAAC ACAGATCAAG 2100
TGAACATTAC ATTGCCATTT TTAATTCATT CTGGTCTTTG AAAGAAATGT ACTACTAAAG 2160
AGCACTAGTT GTGAATTTAG GGTGTTAAAC TTTTTACCAA GTACAAAAAT CCCAAATTCA 2220
CTTTATTATT TTGCTTCAGG ATCCAAGTGA CAAAGTTATA TATTTATAAA ATTGCTATAA 2280
ATCGACAAAA TCTAATGTTG TCTTTTTAAT GTTAGTGATC CACCTGCCTC AGCCTCCCAA 2340
AGTGCTGGGA TTACAGGCTT GAAAGTCTAA CTTTTTTTTA CTTATATATT TGATACATAT 2400
AATTCTTTTG GCTTTGAAAC TTGCAACTTT GAGAACAAAA CAGTCCTTTA AATTTTGCAC 2460
TGCTCAATTC TGTTTTTCGT TTGCATTGTC TTTAATATAA TAAAAGTTAT TACCTTTACA 2520
TATTATCATG TCTATTTTTG ATGACTCATC AATTTTGTCT ATTAAAGATA TTTCTTTAAA 2580
TTAAAAAAAA AAAAAAAAA
Seq ID NO: 442 Protein sequence Protein Accesεion ft: NP 002372.1
11 21 31 41 51
I I I I I
MPRPAPARRL PGLLLLLWPL LLLPSAAPDP VARPGFRRLE TRGPGGSPGR RPSPAAPDGA 60 PASGTSEPGR ARGAGVCKSR PLDLVFIIDS SRSVRPLEFT KVKTFVSRII DTLDIGPADT 120 RVAWNYAST VKIEFQLQAY TDKQSLKQAV GRITPLSTGT MSGLAIQTAM DEAFTVEAGA 180 REPSSNIPKV AIIVTDGRPQ DQVNEVAARA QASGIELYAV GVDRADMASL KMMASEPLEE 240 HVFYVETYGV IEKLSSRFQE TFCALDPCVL GTHQCQHVCI SDGEGKHHCE CSQGYTLNAD 300 KKTCSALDRC ALNTHGCEHI CVNDRSGSYH CECYEGYTLN EDRKTCSAQD KCALGTHGCQ 360 HICVNDRTGS HHCECYEGYT LNADKKTCSV RDKCALGSHG CQHICVSDGA ASYHCDCYPG 420 YTLNEDKKTC SATEEARRLV STEDACGCEA TLAFQDKVSS YLQRLNTKLD DILEKLKINE 480 YGQIHR
Seq ID NO: 443 DNA εequence
Nucleic Acid Accession #: NM_016639.1
Coding sequence: 40..429
1 11 21 31 41 51 J 1 1 1 | 1 | 1 1 1 | 1 GCGGCGGGCG CAGACAGCGG CGGGCGCAGG ACGTGCACTA TGGCTCGGGG CTCGCTGCGC 60
CGGTTGCTGC GGCTCCTCGT GCTGGGGCTC TGGCTGGCGT TGCTGCGCTC CGTGGCCGGG 120
GAGCAAGCGC CAGGCACCGC CCCCTGCTCC CGCGGCAGCT CCTGGAGCGC GGACCTGGAC 180
AAGTGCATGG ACTGCGCGTC TTGCAGGGCG CGACCGCACA GCGACTTCTG CCTGGGCTGC 240
GCTGCAGCAC CTCCTGCCCC CTTCCGGCTG CTTTGGCCCA TCCTTGGGGG CGCTCTGAGC 300
CTGACCTTCG TGCTGGGGCT GCTTTCTGGC TTTTTGGTCT GGAGACGATG CCGCAGGAGA 360
GAGAAGTTCA CCACCCCCAT AGAGGAGACC GGCGGAGAGG GCTGCCCAGC TGTGGCGCTG 420
ATCCAGTGAC AATGTGCCCC CTGCCAGCCG GGGCTCGCCC ACTCATCATT CATTCATCCA 480
TTCTAGAGCC AGTCTCTGCC TCCCAGACGC GGCGGGAGCC AAGCTCCTCC AACCACAAGG 540
GGGGTGGGGG GCGGTGAATC ACCTCTGAGG CCTGGGCCCA GGGTTCAGGG GAACCTTCCA 600
AGGTGTCTGG TTGCCCTGCC TCTGGCTCCA GAACAGAAAG GGAGCCTCAC GCTGGCTCAC 660
ACAAAACAGC TGACACTGAC TAAGGAACTG CAGCATTTGC ACAGGGGAGG GGGGTGCCCT 720
CCTTCCTTAG GACCTGGGGG CCAGGCTGAC TTGGGGGGCA GACTTGACAC TAGGCCCCAC 780
TCACTCAGAT GTCCTGAAAT TCCACCACGG GGGTCACCCT GGGGGGTTAG GGACCTATTT 840
TTAACACTAG GGGCTGGCCC ACTAGGAGGG CTGGCCCTAA GATACAGACC CCCCCAACTC 900
CCCAAAGCGG GGAGGAGATA TTTATTTTGG GGAGAGTTTG GAGGGGAGGG AGAATTTATT 960 AATAAAAGAA TCTTTAACTT TAAAAAAAAA AAAAAAAA
Seq ID NO: 444 Protein sequence Protein Accession ft: NP 057723.1
1 11 21 31 41 51
I I I I I I
MARGSLRRLL RLLVLGLWLA LLRSVAGEQA PGTAPCSRGS SWSADLDKCM DCASCRARPH 60 SDFCLGCAAA PPAPFRLLWP ILGGALSLTF VLGLLSGFLV WRRCRRREKF TTPIEETGGE 120 GCPAVALIQ
Seq ID NO: 445 DNA sequence
Nucleic Acid Accession ft: AF322916.1
Coding sequence: 50..4300
11 21 31 41 51 I
GCACTCCGCA GCCTTTAAGG TTCGCGCGGG GGCCAGGCAA GAGTTAGCCA TGAAGAGCCT 60
CAAGTCCCGC CTGAGGAGGC AGGACGTGCC CGGCCCCGCG TCGTCTGGCG CCGCCGCCGC 120 CAGCGCGCAT GCAGCAGATT GGAATAAATA TGATGACCGA TTGATGAAAG CAGCAGAAAG 180
GGGGGATGTA GAAAAAGTGA CCTCAATCCT TGCTAAAAAG GGGGTCAATC CAGGCAAACT 240
AGATGTGGAA GGCAGATCTG TCTTCCATGT TGTGACCTCA AAGGGGAATC TTGAGTGTTT 300
GAATGCCATC CTTATACATG GAGTTGATAT TACAACCAGT GACACTGCAG GGAGAAATGC 360
TCTTCACCTG GCTGCTAAGT ATGGACATGC ATTGTGCCTA CAAAAACTTC TACAGTACAA 420 TTGTCCCACT GAGCATGCAG ACCTGCAGGG AAGAACTGCA CTTCAAAAAA AAGCAATGGC 480
AGATTGTCCT TCTAGCATAC AGCTGCTTTG TGACCATGGG GCCTCTGTGA ATGCCAAAGA 540
TGTAAAAGGG CGGACACCAC TTGTTCTGGC TACTCAGATG AGTAGGCCAA CAATATGTCA 600
ACTGCTGATA GATAGAGGAG CGGATGTTAA TTCCAGAGAC AAACAAAACA GAACTGCCCT 660
CATGCTAGGT TGCGAATATG GTTGCAGAGA TGCAGTAGAA GTCTTAATTA AAAATGGTGC 720 TGATATAAGC TTGCTGGATG CGCTTGGCCA TGATAGTTCT TACTATGCAA GAATTGGTGA 780
CAATCTGGAC ATTCTAACCT TGTTGAAGAC TGCATCGGAA AATACCAACA AAGGGAGAGA 840
ACTTTGGAAG AAAGGACCAT CTTTGCAACA GCGAAATTTG ACACACATGC AAGATGAAGT 900
AAATGTGAAG TCACATCAGA GGGAGCATCA AAATATTCAG GATTTGGAGA TTGAAAATGA 960
AGATTTGAAA GAGAGGTTGA GAAAAATTCA GCAAGAACAA AGAATACTTT TGGATAAAGT 1020 CAATGGTTTA CAGTTACAGC TGAATGAGGA AGTTATGGTT GCTGATGATC TGGAAAGCGA 1080
GAGAGAAAAG CTGAAGTCCC TTTTGGCAGC TAAAGAAAAG CAACATGAAG AAAGCTTAAG 1140
GACTATTGAG GCTCTGAAAA ATAGATTTAA ATATTTTGAG AGTGATCATT TAGGATCAGG 1200
AAGTCATTTC AGTAACCGAA AAGAAGATAT GCTTCTTAAA CAAGGTCAGA TGTATATGGC 1260
AGACTCACAG TGTACTTCCC CAGCTATACC AGCCCATATG CAAAGCAGAT CTATGTTAAG 1320 ACCTCTGGAA CTATCTTTAC CCAGTCAAAC GTCATACTCT GAAAATGAAA TTTTAAAGAA 1380
AGAGTTAGAA GCAATGCGAA CTTTCTGTGA GTCAGCAAAA CAAGACCGAC TGAAGCTCCA 1440
AAATGAACTG GCACACAAAG TGGCAGAATG CAAAGCTTTA GCATTAGAAT GTGAAAGGGT 1500
CAAGGAGGAT TCAGATGAAC AGATAAAGCA ATTAGAAGAT GCATTAAAAG ATGTGCAGAA 1560
GAGGATGTAT GAGTCAGAAG GTAAAGTTAA ACAAATGCAG ACCCATTTTC TTGCCCTTAA 1620 AGAACACTTA ACAAGTGAAG CAGCCTCAGG GAATCACAGA CTAACCGAGG AACTGAAGGA 1680
TCAGTTGAAA GACTTGAAAG TAAAATATGA AGGTGCTTCA GCAGAAGTGG GGAAATTAAG 1740
AAACCAAATC AAACAAAATG AGATGATAGT AGAAGAGTTT AAGAGGGATG AAGGCAAGCT 1800
GATAGAAGAA AATAAGCβAT TACAGAAGGA ACTTAGTATG TGTGAAATGG AGCGAGAGAA 1860
GAAAGGAAGA AAGGTCACAG AGATGGAAGG CCAGGCAAAA GAATTGTCAG CGAAGTTGGC 1920 CCTTTCCATT CCAβCTGAAA AATTTGAAAA CATGAAGAGC TCATTATCAA ATGAAGTGAA 1980
TGAGAAAGCA AAAAAATTAG TAGAAATGGA AAGAGAACAT GAAAAATCAC TTAGTGAAAT 2040
TAGACAGTTA AAGAGAGAAC TTGAGAATGT TAAGGCCAAG CTTGCTCAGC ACGTCAAACC 2100
AGAGGAACAT GAACAGGTTA AGAGCAGATT AGAACAGAAA TCAGGAGAAC TTGGGAAGAA 2160
GATCACTGAG TTAACATTGA AAAATCAGAC ACTACAAAAG GAAATTGAAA AAGTTTATTT 2220 GGATAATAAG CTCCTCAAGG AGCAAGCACA TAACTTAACA ATTGAAATGA AAAATCATTA 2280
TGTTCCTTTA AAAGTAAGTG AAGACATGAA AAAGTCACAT GATGCAATTA TTGATGATCT 2340
TAATAGAAAG CTTTTAGATG TAACACAAAA ATATACAGAA AAGAAGTTGG AAATGGAGAA 2400
ATTGCTACTG GAAAATGACA GCTTAAGTAA GGATGTAAGC CGCCTAGAAA CTGTGTTTGT 2460
ACCTCCTGAG AAACATGAAA AAGAGATAAT AGCTCTGAAA TCCAATATTG TTGAACTTAA 2520 GAAACAGCTG TCTGAACTTA AGAAAAAATG TGGTGAAGAC CAGGAGAAAA TACACGCTCT 2580
CACATCTGAA AACACTAACT TGAAGAAGAT GATGAGTAAT CAGTATGTGC CAGTTAAAAC 2640
CCATGAAGAG GTTAAAATGA CACTGAATGA CACGTTAGCC AAAACTAACA GAGAATTATT 2700
AGATGTGAAG AAAAAATTTG AAGATATAAA TCAGGAATTT GTAAAAATAA AAGATAAGAA 2760
TGAAATATTA AAAAGAAACC TGGAAAACAC TCAGAACCAA ATAAAAGCTG AGTACATCAG 2820 CCTGGCAGAG CACGAGGCAA AGATGAGCTC GCTAAGTCAG AGCATGAGAA AGGTGCAGGA 2880
TAGTAATGCT GAAATCTTGG CCAACTACAG AAAAGGCCAA GAAGAGATTG TGACACTGCA 2940
TGCCGAAATT AAAGCCCAGA AGAAGGAGCT CGACACAATA CAAGAATGCA TTAAGGTAAA 3000
ATATGCCCCA ATTGTCAGCT TTGAGGAGTG CGAGAGAAAA TTTAAAGCAA CAGAGAAAGA 3060
ACTAAAAGAC CAGTTATCAG AGCAGACACA AAAGTATAGT GTCAGTGAAG AAGAAGTCAA 3120 GAAAAACAAG CAAGAGAATG ACAAGTTAAA GAAGGAGATT TTTACCCTTC AGAAAGATTT 3180
GAGAGATAAG ACAGTTCTCA TTGAGAAGTC TCATGAAATG GAAAGAGCAT TAAGCAGAAA 3240
AACAGACGAG CTAAACAAAC AGTTAAAAGA CTTGTCACAG AAATACACGG AAGTAAAGAA 3300
TGTGAAAGAG AAGCTAGTAG AAGAAAATGC CAAACAGACT TCTGAGATAC TTGCAGTGCA 3360
AAATCTTTTG CAAAAACAAC ATGTTCCATT GGAACAGGTT GAGGCTCTGA AAAAATCTCT 3420 TAATGGCACA ATTGAAAATC TAAAGGAAGA ACTGAAGAGT ATGCAAAGGT GTTACGAGAA 3480
AGAGCAGCAG ACAGTGACCA AACTGCATCA ATTGTTGGAG AATCAAAAGA ACTCTTCTGT 3540
ACCCCTGGCA GAGCATTTGC AGATTAAAGA AGCATTTGAG AAAGAAGTTG GAATCATAAA 3600
AGCCAGCTTG AGAGAAAAGG AAGAAGAAAG CCAAAACAAA ATGGAAGAAG TCTCCAAACT 3660
TCAGTCGGAG GTTCAGAATA CTAAACAAGC ATTAAAAAAA TTAGAGACTA GAGAGGTAGT 3720 TGACTTGTCT AAATATAAAG CAACAAAAAG TGATTTGGAG ACACAGATTT CTAGCTTAAA 3780
TGAAAAATTG GCCAATCTGA ATAGAAAGTA TGAGGAAGTA TGTGAGGAAG TTTTGCATGC 3840
CAAAAAGAAG GAAATATCTG CAAAAGATGA GAAGGAATTA CTGCATTTCA GCATTGAGCA 3900
AGAAATTAAG GATCAGAAGG AACGATGTGA TAAGTCCTTA ACAACAATCA CAGAGTTACA 3960
AAGAAGAATA CAAGAATCTG CTAAACAAAT AGAAGCAAAA GATAATAAGA TAACTGAACT 4020 GCTTAATGAT GTGGAAAGAT TAAAACAGGC ACTCAATGGC CTTTCCCAAC TCACCTACAC 4080
AAGTGGGAAC CCCACCAAGA GGCAGAGCCA GCTGATTGAC ACTCTGCAGC ACCAAGTGAA 4140
ATCTCTGGAG CAACAGCTGG CCGATGCTGA CAGACAGCAC CAAGAAGTAA TTGCAATTTA 4200
TCGGACACAC CTTCTTAGTG CTGCACAGGG TCACATGGAT GAAGATGTTC AGGAGGCTCT 4260
GCTCCAGATC ATACAAATGC GGCAGGGGCT TGTGTGCTAG CCGTTAGCAC TGACTGCCAG 4320
TATCTGTTTT ATCTTGCTGG TGCTGAACAT TCTTTGTGCA ACTCCATGGT CTTTCTGGGC 4380 CTTACTGTGC TGGTATAATT AAAATAAAAT ATATTTTGTT CTGGGTGT
Seq ID NO: 446 Protein sequence 0 Protein Accession #: AAG49577.1
1 11 21 31 41 51
I I I I I I
MKSLKSRLRR QDVPGPASSG AAAASAHAAD WNKYDDRLMK AAERGDVEKV TSILAKKGVN 60 5 PGKLDVEGRS VFH TSKGN LECLNAILIH GVDITTSDTA GRNALHLAAK YGHALCLQKL 120
LQYNCPTEHA DLQGRTALQK KAMADCPSSI QLLCDHGASV NAKDVKGRTP LVLATQMSRP 180
TICQLLIDRG ADVNSRDKQN RTALMLGCEY GCRDAVEVLI KNGADISLLD ALGHDSSYYA 240
RIGDNLDILT LLKTASENTN KGRELWKKGP SLQQRNLTHM QDEVNVKSHQ REHQNIQDLE 300
IENEDLKERL RKIQQEQRIL LDKVNGLQLQ LNEEVMVADD LESEREKLKS LLAAKEKQHE 360 0 ESLRTIEALK NRFKYFESDH LGSGSHFSNR KEDMLLKQGQ MYMADSQCTS PGIPAHMQSR 420
SMLRPLELSL PSQTSYSENE ILKKELEAMR TFCESAKQDR LKLQNELAHK VAECKALALE 480
CERVKEDSDE QIKQLEDALK DVQKRMYESE GKVKQMQTHF LALKEHLTSE AASGNHRLTE 540
ELKDQLKDLK VKYEGASAEV GKLRNQIKQN EMIVEEFKRD EGKLIEENKR LQKELSMCEM 600
EREKKGRKVT EMEGQAKELS AKLALSIPAE KFENMKSSLS NEVNEKAKKL VEMEREHEKS 660 5 LSEIRQLKRE LENVKAKLAQ HVKPEEHEQV KSRLEQKSGE LGKKITELTL KNQTLQKEIE 720
KVYLDNKLLK EQAHNLTIEM KNHYVPLKVS EDMKKSHDAI IDDLNRKLLD VTQKYTEKKL 780
EMEKLLLEND SLSKDVSRLE TVFVPPEKHE KEIIALKSNI VELKKQLSEL KKKCGEDQEK 840
IHALTSENTN LKKMMSNQYV PVKTHEEVKM TLNDTLAKTN RELLDVKKKF EDINQEFVKI 900
KDKNEILKRN LENTQNQIKA EYISLAEHEA KMSSLSQSMR KVQDSNAEIL ANYRKGQEEI 960 0 VTLHAEIKAQ KKELDTIQEC IKVKYAPIVS FEECERKFKA TEKELKDQLS EQTQKYSVSE 1020
EEVKKNKQEN DKLKKEIFTL QKDLRDKTVL IEKSHEMERA LSRKTDELNK QLKDLSQKYT 1080
EVKNVKEKLV EENAKQTSEI LAVQNLLQKQ HVPLEQVEAL KKSLNGTIEN LKEELKSMQR 1140
CYEKEQQTVT KLHQLLENQK NSSVPLAEHL QIKEAFEKEV GIIKASLREK EEESQNKMEE 1200
VSKLQSEVQN TKQALKKLET REWDLSKYK ATKSDLETQI SSLNEKLANL NRKYEEVCEE 1260 5 VLHAKKKEIS AKDEKELLHF SIEQEIKDQK ERCDKSLTTI TELQRRIQES AKQIEAKDNK 1320
ITELLNDVER LKQALNGLSQ LTYTSGNPTK RQSQLIDTLQ HQVKSLEQQL ADADRQHQEV 1380 IAIYRTHLLS AAQGHMDEDV QEALLQIIQM RQGLVC
Seq ID NO: 447 DNA sequence 0 Nucleic Acid Accession #: NM 003020.1
Coding sequence: 29.-664
1 11 21 31 41 51 5 I I I I I I
CGCTCCTCGG GCTGCCCCTC GGTTGACAAT GGTCTCCAGG ATGGTCTCTA CCATGCTATC 60
TGGCCTACTG TTTTGGCTGG CATCTGGATG GACTCCAGCA TTTGCTTACA GCCCCCGGAC 120
CCCTGACCGG GTCTCAGAAG CAGATATCCA GAGGCTGCTT CATGGTGTTA TGGAGCAATT 180
GGGCATTGCC AGGCCCCGAG TGGAATATCC AGCTCACCAG GCCATGAATC TTGTGGGCCC 240
CCAGAGCATT GAAGGTGGAG CTCATGAAGG ACTTCAGCAT TTGGGTCCTT TTGGCAACAT 300 0 CCCCAACATC GTGGCAGAGT TGACTGGAGA CAACATTCCT AAGGACTTTA GTGAGGATCA 360
GGGGTACCCA GACCCTCCAA ATCCCTGTCC TGTTGGAAAA ACAGATGATG GATGTCTAGA 420
AAACACCCCT GACACTGCAG AGTTCAGTCG AGAGTTCCAG TTGCACCAGC ATCTCTTTGA 480
TCCGGAACAT GACTATCCAG GCTTGGGCAA GTGGAACAAG AAACTCCTTT ACGAGAAGAT 540
GAAGGGAGGA GAGAGACGAA AGCGGAGGAG TGTCAATCCA TATCTACAAG GACAGAGACT 600 5 GGATAATGTT GTTGCAAAGA AGTCTGTCCC CCATTTTTCA GATGAGGATA AGGATCCAGA 660
GTAAAGAGAA GATGCTAGAC GAAAACCCAC ATTACCTGTT AGGCCTCAGC ATGGCTTATG 720
TGCACGTGTA AATGGAGTCC CTGTGAATGA CAGCATGTTT CTTACATAGA TAATTATGGA 780
TACAAAGCAG CTGTATGTAG ATAGTGTATT GTCTTCACAC CGATGATTCT GCTTTTTGCT 840
AAATTAGAAT AAGAGCTTTT TTGTTTCTTG GGTTTTTAAA ATGTGAATCT GCAATGATCA 900 0 TAAAAATTAA AATGTGAATG TCAACAATAA AAAGCAAGAC TATGAAAGGC TCAGATTTGT 960
TGCAGTTTAA AATGGTGTCT GAGGTTGTAC TATTTTGGCC AAGTCTGTAG AAAGCTGTCA 1020
TTTGATTTTG ATTATGTAGT TCATCCAGCC CTTGGGCATT GTTATACACC AGTAAAGAAG 1080
GCTGTACTCA AGAGGAGGAG CTGACACATT TCACTTGGCT GCGTCTTAAT AAACATGAAT 1140 GCAAGCATTG GC
65
Seq ID NO: 448 Protein sequence Protein Acceεεion ft: NP 003011.1
__, 1 11 21 31 41 51
70 i i i i i i
MVSRMVSTML SGLLFWLASG WTPAFAYSPR TPDRVSEADI QRLLHGVMEQ LGIARPRVEY 60
PAHQAMNLVG PQSIEGGAHE GLQHLGPFGN IPNIVAELTG DNIPKDFSED QGYPDPPNPC 120
PVGKTDDGCL ENTPDTAEFS REFQLHQHLF DPEHDYPGLG KWNKKLLYEK MKGGERRKRR 180 SVNPYLQGQR LDN AKKSV PHFSDEDKDP E
75
Seq ID NO: 449 DNA εequence
Nucleic Acid Accession ft: NM_003816.1
Coding sequence: 79..2538
80 1 11 21 31 41 51
I I I I I I
CGGCAGGGTT GGAAAATGAT GGAAGAGGCG GAGGTGGAGG CGACCGAGTG CTGAGAGGAA 60 CCTGCGGAAT CGGCCGAGAT GGGGTCTGGC GCGCGCTTTC CCTCGGGGAC CCTTCCTGTC 120 CGGTGGTTGC TGTTGCTTGG CCTGGTGGGC CCAGTCCTCG GTGCGGCGCG GCCAGGCTTT 180 CAACAGACCT CACATCTTTC TTCTTATGAA ATTATAACTC CTTGGAGATT AACTAGAGAA 240 AGAAGAGAAG CCCCTAGGCC CTATTCAAAA CAAGTATCTT ATGTTATTCA GGCTGAAGGA 300 AAAGAGCATA TTATTCACTT GGAAAGGAAC AAAGACCTTT TGCCTGAAGA TTTTGTGGTT 360 TATACTTACA ACAAGGAAGG GACTTTAATC ACTGACCATC CCAATATACA GAATCATTGT 420 CATTATCGGG GCTATGTGGA GGGAGTTCAT AATTCATCCA TTGCTCTTAG CGACTGTTTT 480 GGACTCAGAG GATTGCTGCA TTTAGAGAAT GCGAGTTATG GGATTGAACC CCTGCAGAAC 540 AGCTCTCATT TTGAGCACAT CATTTATCGA ATGGATGATG TCTACAAAGA GCCTCTGAAA 600 TGTGGAGTTT CCAACAAGGA TATAGAGAAA GAAACTGCAA AGGATGAAGA GGAAGAGCCT 660 CCCAGCATGA CTCAGCTACT TCGAAGAAGA AGAGCTGTCT TGCCACAGAC CCGGTATGTG 720 GAGCTGTTCA TTGTCGTAGA CAAGGAAAGG TATGACATGA TGGGAAGAAA TCAGACTGCT 780 GTGAGAGAAG AGATGATTCT CCTGGCAAAC TACTTGGATA GTATGTATAT TATGTTAAAT 840 ATTCGAATTG TGCTAGTTGG ACTGGAGATT TGGACCAATG GAAACCTGAT CAACATAGTT 900 GGGGGTGCTG GTGATGTGCT GGGGAACTTC GTGCAGTGGC GGGAAAAGTT TCTTATCACA 960
CGTCGGAGAC ATGACAGTGC ACAGCTAGTT CTAAAGAAAG GTTTTGGTGG AACTGCAGGA 1020
ATGGCATTTG TGGGAACAGT GTGTTCAAGG AGCCACGCAG GCGGGATTAA TGTGTTTGGA 1080
CAAATCACTG TGGAGACATT TGCTTCCATT GTTGCTCATG AATTGGGTCA TAATCTTGGA 1140
ATGAATCACG ATGATGGGAG AGATTGTTCC TGTGGAGCAA AGAGCTGCAT CATGAATTCA 1200
GGAGCATCGG GTTCCAGAAA CTTTAGCAGT TGCAGTGCAG AGGACTTTGA GAAGTTAACT 1260
TTAAATAAAG GAGGAAACTG CCTTCTTAAT ATTCCAAAGC CTGATGAAGC CTATAGTGCT 1320
CCCTCCTGTG GTAATAAGTT GGTGGACGCT GGGGAAGAGT GTGACTGTGG TACTCCAAAG 1380
GAATGTGAAT TGGACCCTTG CTGCGAAGGA AGTACCTGTA AGCTTAAATC ATTTGCTGAG 1440
TGTGCATATG GTGACTGTTG TAAAGACTGT CGGTTCCTTC CAGGAGGTAC TTTATGCCGA 1500
GGAAAAACCA GTGAGTGTGA TGTTCCAGAG TACTGCAATG GTTCTTCTCA GTTCTGTCAG 1560
CCAGATGTTT TTATTCAGAA TGGATATCCT TGCCAGAATA ACAAAGCCTA TTGCTACAAC 1620
GGCATGTGCC AGTATTATGA TGCTCAATGT CAAGTCATCT TTGGCTCAAA AGCCAAGGCT 1680
GCCCCCAAAG ATTGTTTCAT TGAAGTGAAT TCTAAAGGTG ACAGATTTGG CAATTGTGGT 1740
TTCTCTGGCA ATGAATACAA GAAGTGTGCC ACTGGGAATG CTTTGTGTGG AAAGCTTCAG 1800
TGTGAGAATG TACAAGAGAT ACCTGTATTT GGAATTGTGC CTGCTATTAT TCAAACGCCT 1860
AGTCGAGGCA CCAAATGTTG GGGTGTGGAT TTCCAGCTAG GATCAGATGT TCCAGATCCT 1920
GGGATGGTTA ACGAAGGCAC AAAATGTGGT GCTGGAAAGA TCTGTAGAAA CTTCCAGTGT 1980
GTAGATGCTT CTGTTCTGAA TTATGACTGT GATGTTCAGA AAAAGTGTCA TGGACATGGG 2040
GTATGTAATA GCAATAAGAA TTGTCACTGT GAAAATGGCT GGGCTCCCCC AAATTGTGAG 2100
ACTAAAGGAT ACGGAGGAAG TGTGGACAGT GGACCTACAT ACAATGAAAT GAATACTGCA 2160
TTGAGGGACG GACTTCTGGT CTTCTTCTTC CTAATTGTTC CCCTTATTGT CTGTGCTATT 2220
TTTATCTTCA TCAAGAGGGA TCAACTGTGG AGAAGCTACT TCAGAAAGAA GAGATCACAA 2280
ACATATGAGT CAGATGGCAA AAATCAAGCA AACCCTTCTA GACAGCCGGG GAGTGTTCCT 2340
CGACATGTTT CTCCAGTGAC ACCTCCCAGA GAAGTTCCTA TATATGCAAA CAGATTTGCA 2400
GTACCAACCT ATGCAGCCAA GCAACCTCAG CAGTTCCCAT CAAGGCCACC TCCACCACAA 2460
CCGAAAGTAT CATCTCAGGG AAACTTAATT CCTGCCCGTC CTGCTCCTGC ACCTCCTTTA 2520
TATAGTTCCC TCACTTGATT TTTTTAACCT TCTTTTTGCA AATGTCTTCA GGGAACTGAG 2580
CTAATACTTT TTTTTTTTCT TGATGTTTTC TTGAAAAGCC TTTCTGTTGC AACTATGAAT 2640
GAAAACAAAA CACCACAAAA CAGACTTCAC TAACACAGAA AAACAGAAAC TGAGTGTGAG 2700
AGTTGTGAAA TACAAGGAAA TGCAGTAAAG CCAGGGAATT TACAATAACA TTTCCGTTTC 2760
CATCATTGAA TAAGTCTTAT TCAGTCATCG GTGAGGTTAA TGCACTAATC ATGGATTTTT 2820
TGAACATGTT ATTGCAGTGA TTCTCAAATT AACTGTATTG GTGTAAGATT TTTGTCATTA 2880
AGTGTTTAAG TGTTATTCTG AATTTTCTAC CTTAGTTATC ATTAATGTAG TTCCTCATTG 2940
AACATGTGAT AATCTAATAC CTGTGAAAAC TGACTAATCA GCTGCCAATA ATATCTAATA 3000
TTTTTCATCA TGCACGAATT AATAATCATC ATACTCTAGA ATCTTGTCTG TCACTCACTA 3060
CATGAATAAG CAAATATTGT CTTCAAAAGA ATGCACAAGA ACCACAATTA AGATGTCATA 3120
TTATTTTGAA AGTACAAAAT ATACTAAAAG AGTGTGTGTG TATTCACGCA GTTACTCGCT 3180
TCCATTTTTA TGACCTTTCA ACTATAGGTA ATAACTCTTA GAGAAATTAA TTTAATATTA 3240
GAATTTCTAT TATGAATCAT GTGAAAGCAT GACATTCGTT CACAATAGCA CTATTTTAAA 3300
TAAATTATAA GCTTTAAGGT ACGAAGTATT TAATAGATCT AATCAAATAT GTTGATTCAT 3360
GGCTATAATA AAGCAGGAGC AATTATAAAA TCTTCAATCA ATTGAACTTT TACAAAACCA 3420
CTTGAGAATT TCATGAGCAC TTTAAAATCT GAACTTTCAA AGCTTGCTAT TAAATCATTT 3480
AGAATGTTTA CATTTACTAA βGTGTGCTGG GTCATGTAAA ATATTAGACA CTAATATTTT 3540
CATAGAAATT AGGCTGGAGA AAGAAGGAAG AAATGGTTTT CTTAAATACC TACAAAAAAG 3600
TTACTGTGGT ATCTATGAGT TATCATCTTA GCTGTGTTAA AAATGAATTT TTACTATGGC 3660
AGATATGGTA TGGATCGTAA AATTTTAAGC ACTAAAAATT TTTTCATAAC CTTTCATAAT 3720
AAAGTTTAAT AATAGGTTTA TTAACTGAAT TTCATTAGTT TTTTAAAAGT GTTTTTGGTT 3780
TGTGTATATA TACATATACA AATACAACAT TTACAATAAA TAAAATACTT GAAATTCTCA 3840 AAAAAAAAAA AAAAAAAAAA AAAAA
Seq ID NO: 450 Protein sequence Protein Accesεion #: NP 003807.1
11 21 31 41 51
I
MGSGARFPSG T ILRVRWLLLL I
G ILVGPVLGAA R IPGFQQTSHL I
SSYEIITPWR LTRERREAPR 60 PYSKQVSYVI QAEGKEHIIH LERNKDLLPE DFWYTYNKE GTLITDHPNI QNHCHYRGYV 120 EGVHNSSIAL SDCFGLRGLL HLENASYGIE PLQNSSHFEH IIYRMDDVYK EPLKCGVSNK 180 DIEKETAKDE EEEPPSMTQL LRRRRAVLPQ TRYVELFIW DKERYDMMGR NQTAVREEMI 240 LLANYLDSMY IMLNIRIVLV GLEIWTNGNL INIVGGAGDV LGNFVQWREK FLITRRRHDS 300 AQLVLKKGFG GTAGMAFVGT VCSRSHAGGI NVFGQITVET FASIVAHELG HNLGMNHDDG 360 RDCSCGAKSC IMNSGASGSR NFSSCSAEDF EKLTLNKGGN CLLNIPKPDE AYSAPSCGNK 420 LVDAGEECDC GTPKECELDP CCEGSTCKLK SFAECAYGDC CKDCRFLPGG TLCRGKTSEC 480 DVPEYCNGSS QFCQPDVFIQ NGYPCQNNKA YCYNGMCQYY DAQCQVIFGS KAKAAPKDCF 540 IEVNSKGDRF GNCGFSGNEY KKCATGNALC GKLQCENVQE IPVFGIVPAI IQTPSRGTKC 600 WGVDFQLGSD VPDPGMVNEG TKCGAGKICR NFQCVDASVL NYDCDVQKKC HGHGVCNSNK 660 NCHCENGWAP PNCETKGYGG SVDSGPTYNE MNTALRDGLL VFFFLIVPLI VCAIFIFIKR 720 DQLWRSYFRK KRSQTYESDG KNQANPSRQP GSVPRHVSPV TPPREVPIYA NRFAVPTYAA 780 KQPQQFPSRP PPPQPKVSSQ GNLIPARPAP APPLYSSLT Seq ID NO: 451 DNA sequence
Nucleic Acid Accession ft: NM_0166S0.1
Coding sequence: 196..789
1 11 21 31 41 51
I I I I I I
GGTTTCAATA TATGCAGATG TCTCGATATA GGAATGAAAT TACGTCTTTG GAACAACTTA 60
AATAAGTCAA ATATACTTGG AGCTTTAAAA ATTAAAAGGA GAGAGATTCG AGCACCTTTT 120
CTGCTGCCAT GACAACCATG CAAGGAATGG AACAGGCCAT GCCAGGGTTG GCCTGGTGTG 180
CCCCAGCTGG GAAACATGGC TGTCATACAT TCACATCTGT GGAAAGGATT GCAAGAGAAG 240
TTCTTGAAGG GAGAACCCAA AGTCCTTGGG GTTGTGCAGA TTCTGACTGC CCTGATGAGC 300
CTTAGCATGG GAATAACAAT GATGTGTATG GCATCTAATA CTTATGGAAG TAACCCTATT 360
TCCGTGCATA TCGGGTACAC AATTTGGGGG TCAGTAATGT TTATTATTTC AGGATCCTTG 420
TCAATTGCAG CAGGAATTAG AACTACAAAA GGCCTGGTCC GAGGTAGTCT AGGAATGAAT 480
ATCACCAGCT CTGTACTGGC TGCATCAGGG ATCTTAATCA ACACATTTAG CTTGGCGTTT 540
TATTCATTCC ATCACCCTTA CTGTAACTAC TATGGCAACT CAAATAATTG TCATGGGACT 600
ATGTCCATCT TAATGGGTCT GGATGGCATG GTGCTCCTCT TAAGTGTGCT GGAATTCTGC 660
ATTGCTGTGT CCCTCTCTGC CTTTGGATGT AAAGTGCTCT GTTGTACCCC TGGTGGGGTT 720
GTGTTAATTC TGCCATCACA TTCTCACATG GCAGAAACAG CATCTCCCAC ACCACTTAAT 780
GAGGTTTGAG GCCAACAAAA GATCAACAGA CAAATGCTCC AGAAATCTAT GCTGACTGTG 840
ACACAAGAGC CTCACATGAG AAATTACCAG TATCCAACTT CGATACTGAT AGACGTGTTG 900
ATATTATTAT TATATG AAT CCAATTATGA ACTGTGTGTG TATAGAGAGA TAATAAATTC 960
AAAATTATGT TCTCATTTTT TTCCCTGGAA CTCAATAACT CACTTCACTG GCTCTTTATC 1020 GAGAGTACTA GGAGTTAAAT TAATAAATAA TGCATTTAAT GAGGCCACAG GAAAAA
Seq ID NO: 452 Protein sequence Protein Accession if: NP 057734.1
1 11 21 31 41 51 i i i i i i
MAVIHSHLWK GLQEKFLKGE PKVLGWQIL TALMSLSMGI TMMCMASNTY GSNPISVHIG 60
YTIWGSVMFI ISGSLSIAAG IRTTKGLVRG SLGMNITSSV LAASGILINT FSLAFYSFHH 120
PYCNYYGNSN NCHGTMSILM GLDGMVLLLS VLEFCIAVSL SAFGCKVLCC TPGGWLILP 180 SHSHMAETAS PTPLNEV
Seq ID NO: 453 DNA sequence
Nucleic Acid Accession it: NM_002091.1
Coding sequence: 56..503
1 11 21 31 41 51
I I I I I I
AGTCTCTGCT CTTCCCAGCC TCTCCGGCGC GCTCCAAGGG CTTCCCGTCG GGACCATGCG 60
CGGCAGTGAG CTCCCGCTGG TCCTGCTGGC GCTGGTCCTC TGCCTAGCGC CCCGGGGGCG 120
AGCGGTCCCG CTGCCTGCGG GCGGAGGGAC CGTGCTGACC AAGATGTACC CGCGCGGCAA 180
CCACTGGGCG GTGGGGCACT TAATGGGGAA AAAGAGCACA GGGGAGTCTT CTTCTGTTTC 240
TGAGAGAGGG AGCCTGAAGC AGCAGCTGAG AGAGTACATC AGGTGGGAAG AAGCTGCAAG 300
GAATTTGCTG GGTCTCATAG AAGCAAAGGA GAACAGAAAC CACCAGCCAC CTCAACCCAA 360
GGCCTTGGGC AATCAGCAGC CTTCGTGGGA TTCAGAGGAT AGCAGCAACT TCAAAGATGT 420
AGGTTCAAAA GGCAAAGTTG GTAGACTCTC TGCTCCAGGT TCTCAACGTG AAGGAAGGAA 480
CCCCCAGCTG AACCAGCAAT GATAATGATG GCCTCTCTCA AAAGAGAAAA ACAAAACCCC 540
TAAGAGACTG AGTTCTGCAA GCATCAGTTC TACGGATCAT CAACAAGATT TCCTTGTGCA 600
AAATATTTGA CTATTCTGTA TCTTTCATCC TTGACTAAAT TCGTGATTTT CAAGCAGCAT 660
CTTCTGGTTT AAACTTGTTT GCTGTGAACA ATTGTCGAAA AGAGTCTTCC AATTAATGCT 720
TTTTTATATC TAGGCTACCT GTTGGTTAGA TTCAAGGCCC CGAGCTGTTA CCATTCACAA 780 TAAAAGCTTA AACACAT
Seq ID NO: 454 Protein sequence Protein Accession #: NP_002082.1
1 11 21 31 41 51
I I I I I I
MRGSELPLVL LALVLCLAPR GRAVPLPAGG GTVLTKMYPR GNHWAVGHLM GKKSTGESSS 60 VSERGSLKQQ LREYIRWEEA ARNLLGLIEA KENRNHQPPQ PKALGNQQPS WDSEDSSNFK 120 DVGSKGKVGR LSAPGSQREG RNPQLNQQ
Seq ID NO: 455 DNA sequence
Nucleic Acid Accession ft: NM_016522.l
Coding sequence: 265..1299
1 11 21 31 41 51
I I I I I I
GCGGAAGCAG CGAGGAGGGA GCCCCCTTTG GCCGTCCTCC GTGGAACCGG TTTTCCGAGG 60
CTGGCAAAAG CCGAGGCTGG ATTTGGGGGA GGAATATTAG ACTCGGAGGA GTCTGCGCGC 120
TTTTCTCCTC CCCGCGCCTC CCGGTCGCCG CGGGTTCACC GCTCAGTCCC CGCGCTCGCT 180
CCGCACCCCA CCCACTTCCT GTGCTCGCCC GGGGGGCGTG TGCCGTGCGG CTGCCGGAGT 240
TCGGGGAAGT TGTGGCTGTC GAGAATGGGG GTCTGTGGGT ACCTGTTCCT GCCCTGGAAG 300
TGCCTCGTGG TCGTGTCTCT CAGGCTGCTG TTCCTTGTAC CCACAGGAGT GCCCGTGCGC 360
AGCGGAGATG CCACCTTCCC CAAAGCTATG GACAACGTGA CGGTCCGGCA GGGGGAGAGC 420
GCCACCCTCA GGTGCACTAT TGACAACCGG GTCACCCGGG TGGCCTGGCT AAACCGCAGC 480
ACCATCCTCT ATGCTGGGAA TGACAAGTGG TGCCTGGATC CTCGCGTGGT CCTTCTGAGC 540
AACACCCAAA CGCAGTACAG CATCGAGATC CAGAACGTGG ATGTGTATGA CGAGGGCCCT 600
TACACCTGCT CGGTGCAGAC AGACAACCAC CCAAAGACCT CTAGGGTCCA CCTCATTGTG 660
CAAGTATCTC CCAAAATTGT AGAGATTTCT TCAGATATCT CCATTAATGA AGGGAACAAT 720
ATTAGCCTCA CCTGCATAGC AACTGGTAGA CCAGAGCCTA CGGTTACTTG GAGACACATC 780 TCTCCCAAAG CGGTTGGCTT TGTGAGTGAA GACGAATACT TGGAAATTCA GGGCATCACC 840 CGGGAACAGT CAGGGGACTA CGAGTGCAGT GCCTCCAATG ACGTGGCCGC GCCCGTGGTA 900 CGGAGAGTAA AGGTCACCGT GAACTATCCA CCATACATTT CAGAAGCCAA GGGTACAGGT 960 GTCCCCGTGG GACAAAAGGG GACACTGCAG TGTGAAGCCT CAGCAGTCCC CTCAGCAGAA 1020 TTCCAGTGGT ACAAGGATGA CAAAAGACTG ATTGAAGGAA AGAAAGGGGT GAAAGTGGAA 1080 AACAGACCTT TCCTCTCAAA ACTCATCTTC TTCAATGTCT CTGAACATGA CTATGGGAAC 1140 TACACTTGCG TGGCCTCCAA CAAGCTGGGC CACACCAATG CCAGCATCAT GCTATTTGGT 1200 CCAGGCGCCG TCAGCGAGGT GAGCAACGGC ACGTCGAGGA GGGCAGGCTG CGTCTGGCTG 1260 CTGCCTCTTC TGGTCTTGCA CCTGCTTCTC AAATTTTGAT GTGAGTGCCA CTTCCCCACC 1320 CGGGAAAGGC TGCCGCCACC ACCACCACCA ACACAACAGC AATGGCAACA CCGACAGCAA 1380 CCAATCAGAT ATATACAAAT GAAATTAGAA GAAACACAGC CTCATGGGAC AGAAATTTGA 1440 GGGAGGGGAA CAAAGAATAC TTTGGGGGGA AAAGAGTTTT AAAAAAGAAA TTGAAAATTG 1500 CCTTGCAGAT ATTTAGGTAC AATGGAGTTT TCTTTTCCCA AACGGGAAGA ACACAGCACA 1560 CCCGGCTTGG ACCCACTGCA AGCTGCATCG TGCAACCTCT TTGGTGCCAG TGTGGGCAAG 1620 GGCTCAGCCT CTCTGCCCAC AGACTGCCCC CACGTGGAAC ATTCTGGAGC TGGGCATCCC 1680 AAATTCAATC AGTCCATAGA GACGAACAGA ATGAGACCTT CCGGCCCAAG CGTGGCGCTT 1740 CCGGCCCAAG CGTGGCGCTG CGGGCACTTT GGTAGACTGT GCCACCACGG CGTGTGTTGT 1800 GAAACGTGAA ATAAAAAGAG CAAAAAAAAA AAAAAAAAA
Seq ID NO: 456 Protein sequence Protein Accession #: NP 057606.1
1 11 21 31 41 51 1 1 1 1 11 11 11 | 1
MGVCGYLFLP WKCLVWSLR LLFLVPTGVP VRSGDATFPK AMDNVTVRQG ESATLRCTID 60
NRVTRVAWLN RSTILYAGND KWCLDPRWL LSNTQTQYSI EIQNVDVYDE GPYTCSVQTD 120
NHPKTSRVHL IVQVSPKIVE ISSDISINEG NNISLTCIAT GRPEPTVTWR HISPKAVGFV 180
SEDEYLEIQG ITREQSGDYE CSASNDVAAP WRRVKVTVN YPPYISEAKG TGVPVGQKGT 240
LQCEASAVPS AEFQWYKDDK RLIEGKKGVK VENRPFLSKL IFFNVSEHDY GNYTCVASNK 300
LGHTNASIML FGPGAVSEVS NGTSRRAGCV WLLPLLVLHL LLKF
Seq ID NO : 457 DNA sequence
Nucleic Acid Accession ft: NM_012261.1 Coding sequence: 203..1045
11 21 31 41 51
I I
GATTTGCTCT G ICCAGCAGCT G ITCGGTGCCG CGCTGGACAC I
CGAGTCCTAG CTAGGCGCTC 60 ACAGAATACG CGCTCCCTCC CTCCCCCTTC TCTGTCCCCC GCCTCTCGCT CACCCCGGCC 120 CACTCCAGCG GCGACTTTGA GGGATTCCCT CTCTGGCGGC CTCTGCAGCA GCACAGCCGG 180 CCTCATTCGG GGCAGTGCGA GTATGGATCT CCAAGGAAGA GGGGTCCCCA GCATCGACAG 240 ACTTCGAGTT CTCCTGATGT TGTTCCATAC AATGGCTCAA ATCATGGCAG AACAAGAAGT 300 GGAAAATCTC TCAGGCCTTT CCACTAACCC TGAAAAAGAT ATATTTGTGG TGCGGGAAAA 360 TGGGACGACG TGTCTCATGG CAGAGTTTGC AGCCAAATTT ATTGTACCTT ATGATGTGTG 420 GGCCAGCAAC TACGTAGATC TGATCACAGA ACAGGCCGAT ATCGCATTGA CCCGGGGAGC 480 TGAGGTGAAG GGCCGCTGTG GGCAGAGCCA GTCGGAGCTG CAAGTGTTCT GGGTGGATCG 540 CGCATATGCA CTCAAAATGC TCTTTGTAAA GGAAAGCCAC AACATGTCCA AGGGACCTGA 600 GGCGACTTGG AGGCTGAGCA AAGTGCAGTT TGTCTACGAC TCCTCGGAGA AAACCCACTT 660 CAAAGACGCA GTCAGTGCTG GGAAGCACAC AGCCAACTCG CACCACCTCT CTGCCTTGGT 720 CACCCCCGCT GGGAAGTCCT ATGAGTGTCA AGCTCAACAA ACCATTTCAC TGGCCTCTAG 780 TGATCCGCAG AAGACGGTCA CCATGATCCT GTCTGCGGTC CACATCCAAC CTTTTGACAT 840 TATCTCAGAT TTTGTCTTCA GTGAAGAGCA TAAATGCCCA GTGGATGAGC GGGAGCAACT 900 GGAAGAAACC TTGCCCCTGA TTTTGβGGCT CATCTTGGGC CTCGTCATCA TGGTAACACT 960 CGCGATTTAC CACGTCCACC ACAAAATGAC TGCCAACCAG GTGCAGATCC CTCGGGACAG 1020 ATCCCAGTAT AAGCACATGG GCTAGAGGCC GTTAGGCAGG CACCCCCTAT TCCTGCTCCC 1080 CCAACTGGAT CAGGTAGAAC AACAAAAGCA CTTTTCCATC TTGTACACGA GATACACCAA 1140 CATAGCTACA ATCAAACAGG CCTGGGTATC TGAGGCTTGC TTGGCTTGTG TCCATGCTTA 1200 AACCCACGGA AGGGGGAGAC TCTTTCGGAT TTGTAGGGTG AAATGGCAAT TATTCTCTCC 1260 ATGCTGGGGA GGAGGGGAGG AGGGTCTCAG ACAGCTTTCG TGCTCATGGT GGCTTGGCTT 1320 TGACTCTCCA AAGAGCAATA AATGCCACTT GGAGCTGTAT CTGGCCCCAA AGTTTAGGGA 1380 TTGAAAACAT GCTTCTTTGA GGAGGAAACC CCTTTAGGTT CAGAAGAATA TGGGGTGCTT 1440 TGCTCCCTTG GACACAGCTG GCTTATCCTA TACAGTTGTC AATGCACACA GAATACAACC 1500 TCATGCTCCC TGCAGCAAGA CCCCTGAAAG TGATTCATGC TTCTGGCTGG CATTCTGCAT 1560 GTTTAGTGAT TGTCTTGGGA ATGTTTCACT GCTACCCGCA TCCAGCGACT GCAGCACCAG 1620 AAAACGACTA ATGTAACTAT GCAGAGTTGT TTGGACTTCT TCCTGTGCCA GGTCCAAGTC 1680 GGGGGACCTG AAGAATCAAT CTGTGTGAGT CTGTTTTTCA AAATGAAATA AAACACACTA 1740 TTCTCTGGC
Seq ID NO: 458 Protein sequence Protein Accession ft: NP 036393.1
1 11 21 31 41 51
I I I I I I
MDLQGRGVPS IDRLRVLLML FHTMAQIMAE QEVENLSGLS TNPEKDIFW RENGTTCLMA 60
EFAAKFIVPY DVWASNYVDL ITEQADIALT RGAEVKGRCG HSQSELQVFW VDRAYALKML 120
FVKESHNMSK GPEATWRLSK VQFVYDSSEK THFKDAVSAG KHTANSHHLS ALVTPAGKSY 180
ECQAQQTISL ASSDPQKTVT MILSAVHIQP FDIISDFVFS EEHKCPVDER EQLEETLPLI 240 LGLILGLVIM VTLAIYHVHH KMTANQVQIP RDRΞQYKHMG
Seq ID NO: 459 DNA sequence
Nucleic Acid Accesεion ft: NM_001169.1
Coding εequence: 85..870
11 21 I I I I I I
TAGGAGATAA GAGTATCTTG CACAGCAGGT GCAGGTTTCC CAGCAGCTCA GGCAAGAGTC 60
CGATGTTTGT GCCATCTGAT CCTGATGTCT GGAGAGATAG CCATGTGTGA GCCTGAATTT 120
GGCAATGACA AGGCCAGGGA GCCGAGCGTG GGTGGCAGGT GGCGAGTGTC CTGGTACGAA 180
CGGTTTGTGC AGCCATGTCT GGTCGAACTG CTGGGCTCTG CTCTCTTCAT CTTCATCGGG 240
TGCCTGTCGG TCATTGAGAA TGGGACGGAC ACTGGCCTGC TGCAGCCGGC CCTGGCCCAC 300
GGGCTGGCTT TGβGGCTCGT GATTGCCACG CTGGGGAATA TCAGTGGTGG ACACTTCAAC 360
CCTGCGGTGT CCCTGGCAGC CATGCTGATC GGAGGCCTCA ACCTGGTGAT GCTCCTCCCG 420
TACTGGGTCT CACAGCTGCT CGGGGGGATG CTCGGGGCTG CCTTGGCCAA GGTGGTGAGT 480
CCTGAGGAGA GGTTCTGGAA TGCATCTGGG GCGGCCTTTG TGACAGTCCA GGAGCAGGGG 540
CAGGTGGCAG GGGCGTTGGT GGCAGAGATC ATCCTGACGA CGCTGCTGGC CCTGGCTGTA 600
TGCATGGGTG CCATCAATGA GAAGACAAAG GGCCCTCTGG CCCCGTTCTC CATCGGCTTT 660
GCCGTCACCG TGGATATCCT GGCTGGGGGC CCTGTGTCTG GAGGCTGCAT GAATCCCGCC 720
CGTGCTTTTG GACCTGCGGT GGTGGCCAAC CACTGGAACT TCCACTGGAT CTACTGGCTG 780
GGCCCACTCC TGGCTGGCCT GCTTGTTGGA CTGCTCATTA GGTGCTTCAT TGGAGATGGG 840
AAGACCCGCC TCATCCTGAA GGCTCGGTGA GCAGAGCTCG TGGGATTCCT GCTGCTCCAG 900
GTGTCCTCAG CTCACCTGTC CCAGACTGAG GACAGGGGAG TTCCTGCATT TCCTGCCAGG 960
GCAGAGGCCC AGAGGAGCGA CCCCCTGCTT CCACTGCTTG GGCCTGCTTT CTCAGATAGA 1020
CTGACTGCTG AGGAGGCTCT AGGTTCTTGG AATTCCTTTG TGCTCATCAG AGACCCCAGC 1080
CTGGGGAACA CGCTGCCCGC ACTGCCCAGA GAGCAGTGCA AACACCACAA CACGAGCGTG 1140
TTTCTTGAGA GGAATGTCCC CGAGTTGGAC AAGGAGGCTG TTTCTGCACA TCAGCTCATT 1200
TCCCGCACCC CATTTCTTGC TTGATTGCTT TGTTGGGGGC CTGGCCACTT CCTTGCTTCT 1260 CAAGCTGACA ATTCTCACTT TGCAATAAAT AGTCCAGTGT TTCCTTCAT
Seq ID NO: 460 Protein εequence Protein Accession # : NP 001160 . 1
1 11 21 31 41 51 I i i i i l
MSGEIAMCEP EFGNDKAREP SVGGRWRVSW YERFVQPCLV ELLGSALFIF IGCLSVIENG 60
TDTGLLQPAL AHGLALGLVI ATLGNISGGH FNPAVSLAAM LIGGLNLVML LPYWVSQLLG 120
GMLGAALAKV VSPEERFWNA SGAAFVTVQE QGQVAGALVA EIILTTLLAL AVCMGAINEK 180
TKGPLAPFSI GFAVTVDILA GGPVSGGCMN PARAFGPAW ANHWNFHWIY WLGPLLAGLL 240 VGLLIRCFIG DGKTRLILKA R
Seq ID NO: 461 DNA sequence Nucleic Acid Accession ft: NM_003226.1 Coding sequence: 2..226
1 11 21 31 41 51
I I I I I I
GATGCTGGGG CTGGTCCTGG CCTTGCTGTC CTCCAGCTCT GCTGAGGAGT ACGTGGGCCT 60
GTCTGCAAAC CAGTGTGCCG TGCCGGCCAA GGACAGGGTG GACTGCGGCT ACCCCCATGT 120
CACCCCCAAG GAGTGCAACA ACCGGGGCTG CTGCTTTGAC TCCAGGATCC CTGGAGTGCC 180
TTGGTGTTTC AAGCCCCTGA CTAGGAAGAC AGAATGCACC TTCTGAGGCA CCTCCAGCTG 240
CCCCTGGGAT GCAGGCTGAG CACCCTTGCC CGGCTGTGAT TGCTGCCAGG CACTGTTCAT 00
CTCAGTTTTT CTGTCCCTTT GCTCCCGGCA AGCTTTCTGC TGAAAGTTCA TATCTGGAGC 360 CTGATGTCTT AACGAATAAA GGTCCCATGC TCCACCCG
Seq ID NO: 462 Protein sequence Protein Accession #: NP_003217.1
1 11 21 31 41 51
I I I I I I
MLGLVLALLS SSSAEEYVGL SANQCAVPAK DRVDCGYPHV TPKECNNRGC CFDSRIPGVP 60 WCFKPLTRKT ECTF
Seq ID NO: 463 DNA sequence
Nucleic Acid Accession ft: NM_002993.1
Coding sequence: 64..408 1 11 21 31 41 51 i i i i i i
GGCACGAGCC AGTCTCCGCG CCTCCACCCA GCTCAGGAAC CCGCGAACCC TCTCTTGACC 60
ACTATGAGCC TCCCGTCCAG CCGCGCGGCC CGTGTCCCGG GTCCTTCGGG CTCCTTGTGC 120
GCGCTGCTCG CGCTGCTGCT CCTGCTGACG CCGCCGGGGC CCCTCGCCAG CGCTGCTCCT 180
GTCTCTGCTG TGCTGACAGA GCTGCGTTGC ACTTGTTTAC GCGTTACGCT GAGAGTAAA'C 240
CCCAAAACGA TTGGTAAACT GCAGGTGTTC CCCGCAGGCC CGCAGTGCTC CAAGGTGGAA 300
GTGGTAGCCT CCCTGAAGAA CGGGAAGCAA GTTTGTCTGG ACCCGGAAGC CCCTTTTCTA 360
AAGAAAGTCA TCCAGAAAAT TTTGGACAGT GGAAACAAGA AAAACTGAGT AACAAAAAAG 420
ACCATGCATC ATAAAATTGC CCAGTCTTCA GCGGAGCAGT TTTCTGGAGA TCCCTGGACC 480
CAGTAAGAAT AAGAAGGAAG GGTTGGTTTT TTTCCATTTT CTACATGGAT TCCCTACTTT 540
GAAGAGTGTG GGGGAAAGCC TACGCTTCTC CCTGAAGTTT ACAGCTCAGC TAATGAAGTA 600
CTAATATAGT ATTTCCACTA TTTACTGTTA TTTTACCTGA TAAGTTATTG AACCCTTTGG 660
CAATTGACCA TATTGTGAGC AAAGAATCAC TGGTTATTAG TCTTTCAATG AATATTGAAT 720
TGAAGATAAC TATTGTATTT CTATCATACA TTCCTTAAAG TCTTACCGAA AAGGCTGTGG 780
ATTTCCTATG GAAATAATGT TTTATTAGTG TGCTGTTGAG GGAGGTATCC TGTTGTTCTT 840
ACTCACTCTT CTCATAAAAT AGGAAATATT TTAGTTCTGT TTTCTTGGGG AATATGTTAC 900
TCTTTACCCT AGGATGCTAT TTAAGTTGTA CTGTATTAGA ACACTGGGTG TGTCATACCG 960
TTATCTGTGC AGAATATATT- TCCTTATTCA GAATTTCTAA AAATTTAAGT TCTGTAAGGG 1020
CTAATATATT CTCTTCCTAT GGTTTTAGAT GTTTGATGTC TTCTTAGTAT GGCATAATGT 1080
CATGATTTAC TCATTAAACT TTGATTTTGT ATGCTATTTT TTCACTATAG GATGACTATA 1140 ATTCTGGTCA CTAAATATAC ACTTTAGATA GATGAAGAAG CCCAAAAACA GATAAATTCC 1200 TGATTGCTAA TTTACATAGA AATGTATTCT CTTGGTTTTT TAAATAAAAG CAAAATTAAC 1260 AATGATCTGT GCTCTGCAAA GTTTTGAAAA TATATTTGAA CAATTTGAAT ATAAATTCAT 1320 CATTTAGTCC TCAAAATATA TACAGCATTG CTAAGATTTT CAGATATCTA TTGTGGATCT 1380 TTTAAAGGTT TTGACCATTT TGTTATGAGG AATTATACAT GTATCACATT CACTATATTA 1440 AAATTGCACT TTTATTTTTT CCTGTGTGTC ATGTTGGTTT TTGGTACTTG TATTGTCATT 1500 TGGAGAAACA ATAAAAGATT TCTAAACCAA AAAAAAAAAA AAAAAAA
Seq ID NO: 464 Protein sequence Protein Accession ft: NP_002984.1
1 11 21 31 41 51
I I I I I I
MSLPSSRAAR VPGPSGSLCA LLALLLLLTP PGPLASAGPV SAVLTELRCT CLRVTLRVNP KTIGKLQVFP AGPQCSKVEV VASLKNGKQV CLDPEAPFLK KVIQKILDSG NKKN
Seq ID NO: 465 DNA sequence
Nucleic Acid Accession ft: NM_002038.2
Coding sequence: 108..500
11 21 31 41 51
GAACCGTTTA CTCGCTGCTG TGCCCATCTA TCAGCAGGCT CCGGGCTGAA GATTGCTTCT 60 CTTCTCTCCT CCAAGGTCTA GTGACGGAGC CCGCGCGCGG CGCCACCATG CGGCAGAAGG 120 CGGTATCGCT TTTCTTGTGC TACCTGCTGC TCTTCACTTG CAGTGGGGTG GAGGCAGGTA 180 AGAAAAAGTG CTCGGAGAGC TCGGACAGCG GCTCCGGGTT CTGGAAGGCC CTGACCTTCA 240 TGGCCGTCGG AGGAGGACTC GCAGTCGCCG GGCTGCCCGC GCTGGGCTTC ACCGGCGCCG 300 GCATCGCGGC CAACTCGGTG GCTGCCTCGC TGATGAGCTG GTCTGCGATC CTGAATGGGG 360 GCGGCGTGCC CGCCGGGGGG CTAGTGGCCA CGCTGCAGAG CCTCGGGGCT GGTGGCAGCA 420 GCGTCGTCAT AGGTAATATT GGTGCCCTGA TGGGCTACGC CACCCACAAG TATCTCGATA 480 GTGAGGAGGA TGAGGAGTAG CCAGCAGCTC CCAGAACCTC TTCTTCCTTC TTGGCCTAAC 540 TCTTCCAGTT AGGATCTAGA ACTTTGCCTT TTTGAGATGG 600 GTTCTCACTA TATTGTCCAG GCTAGAGTGC AGTGGCTATT CACAGATGCG AACATAGTAC 660 ACTGCAGCCT CCAACTCCTA GCCTCAAGTG ATCCTCCTGT CTCAACCTCC CAAGTAGGAT 720 TACAAGCATG CGCCGACGAT GCCCAGAATC CAGAACTTTG TCTATCACTC TCCCCAACAA 780 CCTAGATGTG AAAACAGAAT AAACTTCACC CAGAAAA
Seq ID NO: 466 Protein sequence Protein Acceεεion ft: NP_002029.3
11 21 31 41 51 I
MRQKAVSLFL CYLLLFTCSG VEAGKKKCSE SSDSGSGFWK ALTFMAVGGG LAVAGLPALG 60 FTGAGIAANS VAASLMSWSA ILNGGGVPAG GLVATLQSLG AGGSSWIGN IGALMGYATH 120 KYLDSEEDEE
Seq ID NO: 467 DNA εequence
Nucleic Acid Acceεεion #: NM_003469.2
Coding sequence: 92..1945
11 21 31 41 51
GAAACGGCCC GAGAAGCTCG CCCGGAGAAC GGGGAGGAAT ATGCTGTGGA GCTCCTCTGC 60 CATATAAACA AAAAGAGGAA ATCTTTCAAA CATGGCTGAA GCAAAGACCC ACTGGCTTGG 120 AGCAGCCCTG TCTCTTATCC CTTTAATTTT CCTCATCTCT GGGGCTGAAG CAGCTTCATT 180 TCAGAGAAAC CAGCTGCTTC AGAAAGAACC AGACCTCAGG TTGGAAAATG TCCAAAAGTT 240 TCCCAGTCCT GAAATGATCA GGGCTTTGGA GTACATAGAA AACCTCCGAC AACAAGCTCA 300 TAAGGAAGAA AGCAGCCCAG ATTATAATCC CTACCAAGGT GTCTCTGTCC CCCTTCAGCA 360 AAAAGAAAAT GGCGATGAAA GCCACTTGCC CGAGAGGGAT TCACTGAGTG AAGAAGACTG 420 GATGAGAATA ATACTCGAAG CTTTGAGACA GGCTGAAAAT GAGCCTCAGT CTGCACCAAA 480 AGAAAATAAG CCCTATGCCT TGAATTCAGA AAAGAACTTT CCAATGGACA TGAGTGATGA 540 TTATGAGACA CAGCAGTGGC CAGAAAGAAA GCTTAAGCAC ATGCAATTCC CTCCTATGTA 600 TGAAGAGAAT TCCAGGGATA ACCCCTTTAA ACGCACAAAT GAAATAGTGG AGGAACAATA 660 TACTCCTCAA AGCCTTGCTA CATTGGAATC TGTCTTCCAA GAGCTGGGGA AACTGACAGG 720 ACCAAACAAC CAGAAACGTG AGAGGATGGA TGAGGAGCAA AAACTTTATA CGGATGATGA 780 AGATGATATC TACAAGGCTA ATAACATTGC CTATGAAGAT GTGGTCGGGG GAGAAGACTG 840 GAACCCAGTA GAGGAGAAAA TAGAGAGTCA AACCCAGGAA GAGGTGAGAG ACAGCAAAGA 900 GAATATAGGA AAAAATGAAC AAATCAACGA TGAGATGAAA CGCTCAGGGC AGCTTGGCAT 960 CCAGGAAGAA GATCTTCGGA AAGAGAGTAA AGACCAACTC TCAGATGATG TCTCCAAAGT 1020 AATTGCCTAT TTGAAAAGGT TAGTAAATGC TGCAGGAAGT GGGAGGTTAC AGAATGGGCA 1080 AAATGGGGAA AGGGCCACCA GGCTTTTTGA GAAACCTCTT GATTCTCAGT CTATTTATCA 1140 GCTGATTGAA ATCTCAAGGA ATTTACAGAT ACCCCCAGAA GACTTAATTG AGATGCTCAA 1200 AACTGGGGAG AAGCCGAATG GATCAGTGGA ACCGGAGCGG GAGCTTGACC TTCCTGTTGA 1260 CCTAGATGAC ATCTCAGAGG CTGACTTAGA CCATCCAGAC CTGTTCCAAA ATAGGATGCT 1320 CTCCAAGAGT GGCTACCCTA AAACACCTGG TCGTGCTGGG ACTGAGGCCC TACCAGACGG 1380 GCTCAGTGTT GAGGATATTT TAAATCTTTT AGGGATGGAG AGTGCAGCAA ATCAGAAAAC 1440 GTCGTATTTT CCCAATCCAT ATAACCAGGA GAAAGTTCTG CCAAGGCTCC CTTATGGTGC 1500 TGGAAGATCT AGATCGAACC AGCTTCCCAA AGCTGCCTGG ATTCCACATG TTGAAAACAG 1560 ACAGATGGCA TATGAAAACC TGAACGACAA GGATCAAGAA TTAGGTGAGT ACTTGGCCAG 1620 GATGCTAGTT AAATACCCTG AGATCATTAA TTCAAACCAA GTGAAGCGAG TTCCTGGTCA 1680 AGGCTCATCT GAAGATGACC TGCAGGAAGA GGAACAAATT GAGCAGGCCA TCAAAGAGCA 1740 TTTGAATCAA GGCAGCTCTC AGGAGACTGA CAAGCTGGCC CCGGTGAGCA AAAGGTTCCC 1800 TGTGGGGCCC CCGAAGAATG ATGATACCCC AAATAGGCAG TACTGGGATG AAGATCTGTT 1860 AATGAAAGTG CTGGAATACC TCAATCAAGA AAAGGCAGAA AAGGGAAGGG AGCATATTGC 1920 TAAGAGAGCA ATGGAAAATA TGTAAGCTGC TTTCATTAAT TACCCTACTT TCATTCCTCC 1980
CACCCCAAGC AAATCCCAAC ATTTCTCTTC AGTGTGTTGA CTTCTATCCT GTTAACACTG 2040
TAATATCTTT AAATGATGTA CAGGCAGATG AAACCAGGTC ACTGGGGAGT CTGCTTCATT 2100
TCCTCTGAGC TGTTATCTTG TGTATGGATA TGTGTAAATG TTATGACTCC TTGATAAAAA 2160
ATTTATTATG TCCATTATTC AAGAAAGATA TCTATGACTG TGTTTAATAG TATATCTAAT 2220
GGCTGTGGCA TTGTTGATGC TCACATATGA TAAAAAAGTG TCCTATAATT CTATTGAAAG 2280
TTTTTAATAT TTATTGAATT ATTTTGTTAC TGTCTGTAGC GTTTTGTGGA GTACTGβACC 2340 AAAAAAATAA AGCATTATAA ATATA
10 Seq ID NO: 468 Protein sequence Protein Accession #: NP 003460.1
1 11 21 31 41 51 κ I I I I I I
I D MAEAKTHWLG AALSLIPLIF LISGAEAASF QRNQLLQKEP DLRLENVQKF PSPEMIRALE 60
YIENLRQQAH KEESSPDYNP YQGVSVPLQQ KENGDESHLP ERDSLSEEDW MRIILEALRQ 120
AENEPQSAPK ENKPYALNSE KNFPMDMSDD YETQQWPERK LKHMQFPPMY EENSRDNPFK 180
RTNEIVEEQY TPQSLATLES VFQELGKLTG PNNQKRERMD EEQKLYTDDE DDIYKANNIA 240
YEDWGGEDW NPVEEKIESQ TQEEVRDSKE NIGKNEQIND EMKRSGQLGI QEEDLRKESK 300
20 DQLSDDVSKV IAYLKRLVNA AGSGRLQNGQ NGERATRLFE KPLDSQSIYQ LIEISRNLQI 360
PPEDLIEMLK TGEKPNGSVE PERELDLPVD LDDISEADLD HPDLFQNRML SKSGYPKTPG 420
RAGTEALPDG LSVEDILNLL GMESAANQKT SYFPNPYNQE KVLPRLPYGA GRSRSNQLPK 480
AAWIPHVENR QMAYENLNDK DQELGEYLAR MLVKYPEIIN SNQVKRVPGQ GSSEDDLQEE 540
EQIEQAIKEH LNQGSSQETD KLAPVSKRFP VGPPKNDDTP NRQYWDEDLL MKVLEYLNQE 600
25 KAEKGREHIA KRAMENM
Seq ID NO : 469 DNA sequence
Nucleic Acid Accession ft : NM_006398 . 1
Coding sequence : 19 . .516
30
1 11 21 31 41 51
I I I I I I
GGCCCCTTGT CTGCAGAGAT GGCTCCCAAT GCTTCCTGCC TCTGTβTGCA TGTCCGTTCC 60
GAGGAATGGG ATTTAATGAC CTTTGATGCC AACCCATATG ACAGCGTGAA AAAAATCAAA 120
35 GAACATGTCC GGTCTAAGAC CAAGGTTCCT GTGCAGGACC AGGTTCTTTT GCTGGGCTCC 180
AAGATCTTAA AGCCACGGAG AAGCCTCTCA TCTTATGGCA TTGACAAAGA GAAGACCATC 240
CACCTTACCC TGAAAGTGGT GAAGCCCAGT GATGAGGAGC TGCCCTTGTT TCTTGTGGAG 300
TCAGGTGATG AGGCAAAGAG GCACCTCCTC CAGGTGCGAA GGTCCAGCTC AGTGGCACAA 360
GTGAAAGCAA TGATCGAGAC TAAGACGGGT ATAATCCCTG AGACCCAGAT TGTGACTTGC 420
40 AATGGAAAGA GACTGGAAGA TGGGAAGATG ATGGCAGATT ACGGCATCAG AAAGGGCAAC 480
TTACTCTTCC TGGCATCTTA TTGTATTGGA GGGTGACCAC CCTGββGATG GGGTGTTGGC 540
AGGGGTCAAA AAGCTTATTT CTTTTAATCT CTTACTCAAC GAACACATCT TCTGATGATT 600
TCCCAAAATT AATGAGAATG AGATGAGTAG AGTAAGATTT GGGTGGGATG GGTAGGATGA 660
AGTATATTGC CCAACTCTAT GTTTCTTTGA TTCTAACACA ATTAATTAAG TGACATβATT 720
45 TTTACTAATG TATTACTGAG ACTAGTAAAT AAATTTTTAA GGCAAAATAG AGCATTC
Seq ID NO: 470 Protein sequence Protein Accession ft: NP_006389.1
50 1 11 21 31 41 51
I - I I I I I
MAPNASCLCV HVRSEEWDLM TFDANPYDSV KKIKEHVRSK TKVPVQDQVL LLGSKILKPR 60 RSLSSYGIDK EKTIHLTLKV VKPSDEELPL FLVESGDEAK RHLLQVRRSS SVAQVKAMIE 120 TKTGIIPETQ IVTCNGKRLE DGKMMADYGI RKGNLLFLAS YCIGG
55
Seq ID NO: 471 DNA sequence
Nucleic Acid Accesεion ft: XM_094741.1
Coding sequence: 1..948
60 11 21 31 41 51
A ITGAAGGCCA AICTACAGCGC AIGAGGAGCGC TITTCTCCTGC TIGGGTTTCTC CIGACTGGCCT 60
TCCCTGCAβC CGGTCCTCTT CGCCCTTGTC CTCCTGTGCT ACCTCCTGAC CTTGACGGGC 120
AACTCGGCGC TGGTGCTGCT GGCGGTGCGC GACCCGCGCC TGCACACGCC CATGTACTAC 180
65 TTCCTCTGCC ACCTGGCCTT GGTAGACGCG GGCTTCACTA CTAGCGTGGT GCCGCCGCTG 240
CTGGCCAACC TGCGCGGACC AGCGCTCTGG CTGCCGCGCA GCCACTGCAC GGCCCAGCTG 300
TGCGCATCGC TβGCTCTGGG TTCGGCCGAA TGCGTCCTCC TGGCGGTGAT GGCTCTGGAC 360
CGCGCGGCCG CAβTGTGCCG CCCGCTGCGC TATGCGGGGC TCGTCTCCCC GCGCCTATGT 420
CGCACGCTGG CCAGCβCCTC CTGGCTAAGC GGCCTCACCA ACTCGGTTGC GCAAACCGCG 480
70 CTCCTGGCTG AGCGGCCGCT GTGCGCGCCC CGCCTGCTGG ACCACTTCAT CTGTGAGCTG 540
CCGGCGTTGC TCAAGCTGGC CTGCGGAGGC GACGGAGACA CTACCGAGAA CCAGATGTTC 600
GCCGCCCGCG TGGTCATCCT GCTGCTGCCG TTTGCCGTCA TCCTGGCCTC CTACGGTGCC 660
GTGGCCCGAG CTCTCTGTTG CATGCGGTTC AGCGGAGGCC GGAGGAGGGC GGTGGGCACG 720
TGTGGGTCCC ACCTGACAGC CGTCTGCCTG TTCTACGGCT CGGCCATCTA CACCTACCTG 780
75 CAGCCCGCGC AGCGCTACAA CCAGGCACGG GGCAAGTTCG TATCGCTCTT CTACACCGTG 840
GTCACACCTG CTCTCAACCC GCTCATCTAC ACCCTCAGGA ATAAGAAAGT GAAGGGGGCA 900 GCGAGGAGGC TGCTGCGGAG TCTGGGGAGA GGCCAGGCTG GGCAGTGA
Seq ID NO: 472 Protem sequence
80 Protein Accesεion ft: XP_094741.1
1 .11 21 31 41 51
I I I I I I
MKANYSAEER FLLLGFSDWP SLQPVLFALV LLCYLLTLTG NSALVLLAVR DPRLHTPMYY FLCHLALVDA GFTTS PPL LANLRGPALW LPRSHCTAQL CASLALGSAE CVLLAVMALD 120
RAAAVCRPLR YAGLVSPRLC RTLASASWLS GLTNSVAQTA LLAERPLCAP RLLDHFICEL 180
PALLKLACGG DGDTTENQMF AARWILLLP FAVILASYGA VARAVCCMRF SGGRRRAVGT 240
CGSHLTAVCL FYGSAIYTYL QPAQRYNQAR GKFVSLFYTV VTPALNPLIY TLRNKKVKGA 300 ARRLLRSLGR GQAGQ
Seq ID NO: 473 DNA εequence
Nucleic Acid Accession ft: NM_001062.1
Coding sequence: 76..1380
11 21 31 41 51
I I I I
GCTCTCATTA CCTTCTGCGC ATCACTTAAT AAATAGCCAG CCAATTCATC AACATTCTGG 60 TACACTGTTG GAGAGATGAG ACAGTCACAC CAGCTGCCCC TAGTGGGGCT CTTACTGTTT 120 TCTTTTATTC CAAGCCAACT ATGCGAGATT TGTGAGGTAA GTGAAGAAAA CTACATCCGC 180 CTAAAACCTC TGTTGAATAC AATGATCCAG TCAAACTATA ACAGGGGAAC CAGCGCTGTC 240 AATGTTGTGT TGTCCCTCAA ACTTGTTGGA ATCCAGATCC AAACCCTGAT GCAAAAGATG 300 ATCCAACAAA TCAAATACAA TGTβAAAAGC AGATTGTCAG ATGTAAGCTC GGGAGAGCTT 360 GCCTTGATTA TACTGGCTTT GGGAGTATGT CGTAACGCTG AGGAAAACTT AATATATGAT 420 TACCACCTGA CTGACAAGCT AGAAAATAAA TTCCAAGCAG AAATTGAAAA TATGGAAGCA 480 CACAATGGCA CTCCCCTGAC TAACTACTAC CAGCTCAGCC TGGACGTTTT GGCCTTGTGT 540 CT6TTCAATG GGAACTACTC AACCGCCGAA GTTGTCAACC ACTTCACTCC TGAAAATAAA 600 AACTATTATT TTGGTAGCCA GTTCTCAGTA GATACTGGTG CAATGGCTGT CCTGGCTCTG 660 ACCTGTGTGA AGAAGAGTCT AATAAATGGG CAGATCAAAG CAGATGAAGG CAGTTTAAAG 720 AACATCAGTA TTTATACAAA GTCACTGGTA GAAAAGATTC TGTCTGAGAA AAAAGAAAAT 780 GGTCTCATTG GAAACACATT TAGCACAGGA GAAGCCATGC AGGCCCTCTT TGTATCATCA 840 GACTATTATA ATGAAAATGA CTGGAATTGC CAACAAACTC TGAATACAGT GCTCACGGAA 900 ATTTCTCAAG GAGCATTCAG TAATCCAAAC GCTGCAGCCC AGGTCTTACC TGCCCTGATG 960 GGAAAGACCT TCTTGGATAT TAACAAAGAC TCTTCTTGCG TCTCTGCTTC AGGTAACTTC 1020 AACATCTCCG CTGATGAGCC TATAACTGTG ACACCTCCTG ACTCACAATC ATATATCTCC 1080 GTCAATTACT CTGTGAGAAT CAATGAAACA TATTTCACCA ATGTCACTGT GCTAAATGβT 1140 TCTGTCTTCC TCAGTGTGAT GGAGAAAGCC CAGAAAATGA ATGATACTAT ATTTGGTTTC 1200 ACAATGGAGG AGCGCTCATG GGGGCCCTAT ATCACCTGTA TTCAGGGCCT ATGTGCCAAC 1260 AATAATGACA GAACCTACTG GGAACTTCTG AGTGGAGGCG AACCACTGAG CCAAGGAGCT 1320 GGTAGTTACG TTGTCCGCAA TGGAGAAAAC TTGGAGGTTC GCTGGAGCAA ATACTAATAA 1380 GCCCAAACTT TCCTCAGCTG CATAAAATCC ATTTGCAGTG GAGTTCCATG TTTATTGTCC 1440 TTATGCCTTC TTCTTCATTT ATCCCAGTAC GAGCAGGAGA GTTAATAACC TCCCCTTCTC 1500 TCTCTACATG TTCAATAAAA GTTGTTGAAA GATTAAC
Seq ID NO: 474 Protein sequence Protein Accession #: NP 001053.1
11 21 31 41 51
I I I I I
MRQSHQLPLV GLLLFSFIPS QLCEICEVSE ENYIRLKPLL NTMIQSNYNR GTSAVNWLS 60 LKLVGIQIQT LMQKMIQQIK YNVKSRLSDV SSGELALIIL ALGVCRNAEE NLIYDYHLTD 120 KLENKFQAEI ENMEAHNGTP LTNYYQLSLD VLALCLFNGN YSTAEWNHF TPENKNYYFG 180 SQFSVDTGAM AVLALTCVKK SLINGQIKAD EGSLKNISIY TKSLVEKILS EKKENGLIGN 240 TFSTGEAMQA LFVSSDYYNE NDWNCQQTLN TVLTEISQGA FSNPNAAAQV LPALMGKTFL 300 DINKDSSCVS ASGNFNISAD EPITVTPPDS QSYISVNYSV RINETYFTNV TVLNGSVFLS 360 VMEKAQKMND TIFGFTMEER SWGPYITCIQ GLCANNNDRT YWELLSGGEP LSQGAGSYW 420 RNGENLEVRW SKY
Seq ID NO: 475 DNA sequence Nucleic Acid Acceεsion ft: NM_004852.1 Coding sequence: 89..1546
11 21 31 41 51
I I I
GCCCCCGCCC GCCCCGGGCC CTCATGGACT GAATGAAGGC T 1GCCTACACC GCCTATCGAT 60 GCCTCACCAA AGACCTAGAA CGTGCGCCAT GAACCCGGAG CTGACAATGG AAAGTCTGGG 120 CACTTTGCAC GGCGCGCGCG GCGGCGGCAG TGGCGGGGGC GGCGGCGGGG GCGGCGGGGG 180 CGGCGGCGGG GGCCCGGGCC ATGAGCAGGA GCTGCTGGCC AGCCCCAGCC CCCACCACGC 240 GCGCCGCGβC CCGCGTGGCT CGCTGCGGGG CCCTCCGCCG CCTCCAACCG CGCACCAGGA 300 GCTGGGCACG GCGGCAGCGG CGGCAGCGGC GGCGTCGCGC TCGGCCATGG TCACCAGCAT 360 GGCCTCGATC CTGGACGGCG GCGACTACCG GCCCGAGCTC TCCATCCCGC TGCACCACGC 420 CATGAGCATG TCCTGCGACT CGTCTCCGCC TGGCATGGGC ATGAGCAACA CCTACACCAC 480 GCTGACACCG CTCCAGCCGC TGCCACCCAT CTCCACCGTG TCTGACAAGT TCCACCACCC 540 TCACCCGCAC CACCATCCGC ACCACCACCA CCACCACCAC CACCAGCGCC TGTCCGGCAA 600 CGTCAGCGGC AGCTTCACCC TCATGCGCβA CGAGCGCGGG CTCCCGGCCA TGAACAACCT 660 CTACAGTCCC TACAAGGAGA TGCCCGGCAT GAGCCAGAGC CTGTCCCCGC TGGCCGCCAC 720 GCCGCTGGGC AACGGGCTAG GCG6CCTCCA CAACGCGCAG CAGAGTCTGC CCAACTACGG 780 TCCGCCGGGC CACGACAAAA TGCTCAGCCC CAACTTCGAC GCGCACCACA CTGCCATGCT 840 GACCCGCGGT GAGCAACACC TGTCCCGCGG CCTGGGCACC CCACCTGCGG CCATGATGTC 900 GCACCTGAAC GGCCTGCACC ACCCGGGCCA CACTCAGTCT CACGGGCCGG TGCTGGCACC 960 CAGTCGCGAG CGGCCACCCT CGTCCTCATC GGGCTCGCAG GTGGCCACGT CGGGCCAGCT 1020 GGAAGAAATC AACACCAAAG AGGTGGCCCA GCGCATCACA GCGGAGCTGA AGCGCTACAG 1080 TATCCCCCAG GCGATCTTTG CGCAGAGGGT GCTGTGCCGG TCTCAGGGGA CTCTCTCCGA 1140 CCTGCTCCGG AATCCAAAAC CGTGGAGTAA ACTCAAATCT GGCAGGGAGA CCTTCCβCAG 1200 GATGTGGAAG TGGCTTCAGG AGCCCGAGTT CCAGCGCATG TCCGCCTTAC GCCTGGCAGC 1260 GTGCAAACGC AAAGAGCAAG AACCAAACAA AGACAGGAAC AATTCCCAGA AGAAGTCCCG 1320 CCTGGTGTTC ACTGACCTCC AACGCCGAAC ACTCTTCGCC ATCTTCAAGG AGAACAAACG 1380 CCCGTCAAAG GAGATGCAGA TCACCATTTC CCAGCAGCTG GGCCTGGAGC TCACAACCGT 1440 CAGCAACTTC TTCATGAACG CCCGGCGCCG CAGCCTGGAG AAGTGGCAAG ACGATCTGAG 1500 CACAGGGGGC TCCTCGTCCA CCTCCAGCAC GTGTACCAAA GCATGATGGA AGGACTCTCA 1560 CTTGGGCACA AGTCACCTCC AAATGAGGAC AACAGATACC AAAAGAAAAC AAAGGAAAAA 1620 GACACCGGAT TCCTAGCTGG GGCCCTTCAC TGGTG
Seq ID NO: 476 Protein sequence Protein Accession ft: NP 004843.1
11 21 31 41 51
I I I I I
MNPELTMESL GTLHGARGGG SGGGGGGGGG GGGGGPGHEQ ELLASPSPHH ARRGPRGSLR 60 GPPPPPTAHQ ELGTAAAAAA AASRSAMVTS MASILDGGDY RPELSIPLHH AMSMSCDSSP 120 PGMGMSNTYT TLTPLQPLPP ISTVSDKFHH PHPHHHPHHH HHHHHQRLSG NVSGSFTLMR 180 DERGLPAMNN LYSPYKEMPG MSQSLSPLAA TPLGNβLGGL HNAQQSLPNY GPPGHDKMLS 240 PNFDAHHTAM LTRGEQHLSR GLGTPPAAMM SHLNGLHHPG HTQSHGPVLA PSRERPPSSS 300 SGSQVATSGQ LEEINTKEVA QRITAELKRY SIPQAIFAQR VLCRSQGTLS DLLRNPKPWS 360 KLKSGRETFR RMWKWLQEPE FQRMSALRLA ACKRKEQEPN KDRNNSQKKS RLVFTDLQRR 420 TLFAIFKENK RPSKEMQITI SQQLGLELTT VSNFFMNARR RSLEKWQDDL STGGSSSTSS 480 TCTKA
Seq ID NO: 477 DNA sequence
Nucleic Acid Accession ft: NM_013271.1
Coding sequence: 27..809
11 21 31 41 51
I I I I I
TCCGGAGCCA GGCTCGCTGG GGCAGCATGG CGGGGTCGCC GCTGCTCTGG GGGCCGCGGG 60 CCGGGGGCGT CGGCCTTTTG GTGCTGCTGC TGCTCGGCCT GTTTCGβCCG CCCCCCGCGC 120 TCTGCGCGCG GCCGGTAAAG GAACCCCCCC GCCTAAGCGC AGCGTCTCCG CCCTTGGCTG 180 AGACTGGCGC TCCTCGCCGC TTCCGGCGGT CAGTGCCCCG AGGTGAGGCG GCGGGGGCGG 240 TGCAGGAGCT GGCGCGGGCG CTGGCGCATC TGCTGGAGGC CGAACGTCAG GAGCGGGCGC 300 GGGCCGAGGC GCAGGAGGCT GAGGATCAGC AGGCGCGCGT CCTGGCGCAG CTGCTGCGCG 360 TCTGGGGCGC CCCCCGCAAC TCTGATCCGG CTCTGGGCCT GGACGACGAC CCCGACGCGC 420 CTGCAGCGCA GCTCGCTCGC GCTCTGCTCC GCGCCCGCCT TGACCCTGCC GCCCTAGCAG 480 CCCAGCTTGT CCCCGCGCCC GTCCCCGCCG CGGCGCTCCG ACCCCGGCCC CCG6TCTACG 540 ACGACGGCCC CGCGGGCCCG GATGCTGAGG AGGCAGGCGA CGAGACACCC GACGTGGACC 600 CCGAGCTGTT GAGGTACTTG CTGGGACGGA TTCTTGCGGG AAGCGCGGAC TCCGAGGGGG 660 TGGCAGCCCC GCGCCGCCTC CGCCGTGCCG CCGACCACGA TGTGGGCTCT GAGCTGCCCC 720 CTGAGGGCGT GCTGGGGGCG CTGCTGGGTG TGAAACGCCT AGAGACCCCG GCGCCCCAGG 780 TGCCTGCACG CCGCCTCTTG CCACCCTGAG CACTGCCCGG ATCCCGTGCA CCCTGGGACC 840 CAGAAGT6CC CCCGCCATCC CGCCACCAGG ACTTCTCCCC GCCAGCACGT CCAGAGCAAC 900 TTACCCCGGC CAGCCAGCCC TCTCACCCGA GGATCCCTAC CCCCTGGCCC ACAATAACAT 960 GATCTGAGC
Seq ID NO: 478 Protein sequence Protein Accesεion ft: NP 037403.1
1 11 21 31 41 51
I I I I I I
MAGSPLLWGP RAGGVGLLVL LLLGLFRPPP ALCARPVKEP RGLSAASPPL AETGAPRRFR 60 RSVPRGEAAG AVQELARALA HLLEAERQER ARAEAQEAED QQARVLAQLL RVWGAPRNSD 120 PALGLDDDPD APAAQLARAL LRARLDPAAL AAQLVPAPVP AAALRPRPPV YDDGPAβPDA 180 EEAGDETPDV DPELLRYLLG RILAGSADSE GVAAPRRLRR AADHDVGSEL PPEGVLGALL 240 RVKRLETPAP QVPARRLLPP
Seq ID NO: 479 DNA sequence Nucleic Acid Accession ft: NM_002214 Coding sequence: 681..2990
11 21 31 41 51
I I I I
CCCAGAGCCG CCTCCCCCTG TTGCTGGCAT CCCGAGCTTC CTCCCTTGCC AGCCAGGACG 60 CTGCCGACTT GTCTTTGCCC GCTGCTCCGC AGACGGGGCT GCAAAGCTGC AACTAATGGT 120 GTTGGCCTCC CTGCCCACCT GTGGAAGCAA CTGCGCTGAT TGATGCGCCA CAGACTTTTT 180 TCCCCTCGAC CTCGCCGGCG TACCCTCCCA CAGATCCAGC ATCACCCAGT GAATGTACAT 240 TAGGGTGGTT TCCCCCCCAG CTTCGGGCTT TGTTTGGGTT TGATTGTGTT TGGCTCTTCG 300 CTAAGCTGAT TTATGCAGCA GAAGCCCCAC CGGCTGGAGA GAAACAAAAG CTCTTTTCTT 360 TGTCCCGGAG CAGGCTGCGG AGCCCTTGCA GAGCCCTCTC TCCAGTCGCC GCCGGGCCCT 420 TGβCCGTCGA AGGAGGTGCT TCTCGCGGAG ACCGCGGGAC CCGCCGTGCC GAGCCGGGAG 480 GGCCGTAGGG GCCCTGAGAT GCCGAGCGGT GCCCGGGCCC GCTTACCTGC ACCGCTTGCT 540 CCGAGCCGCG GGGTCCCCCT GCTAGGCCTG CGGAAAACGT CCTAGCGACA CTCGCCCGCG 600 GGCCCCGAGG TCGCCCGGGA GGCCGAGCCC GCGTCCGGAA GGCAGCCAGG CGGCGGGCGC 660 GGGGCGGGCT GTTTTGCATT ATGTGCGGCT CGGCCCTGGC TTTTTTTACC GCTGCATTTG 720 TCTGCCTGCA AAACGACCGG CGAGGTCCCG CCTCGTTCCT CTGGGCAGCC TGGGTGTTTT 780 CACTTGTTCT TGGACTGGGC CAAGGTGAAG ACAATAGATG TGCATCTTCA AATGCAGCAT 840 CCTGTGCCAG GTGCCTTGCG CTGGGTCCAG AATGTGGATG GTGTGTTCAA GAGβATTTCA 900 TTTCAGGTGG ATCAAGAAGT GAACGTTGTG ATATTGTTTC CAATTTAATA AGCAAAGGCT 960 GCTCAGTTGA TTCAATAGAA TACCCATCTG TGCATGTTAT AATACCCACT GAAAATGAAA 1020 TTAATACCCA GGTGACACCA GGAGAAGTGT CTATCCAGCT GCGTCCAGGA GCCGAAGCTA 1080 ATTTTATGCT GAAAGTTCAT CCTCTGAAGA AATATCCTGT GGATCTTTAT TATCTTGTTG 1140 ATGTCTCAGC ATCAATGCAC AATAATATAG AAAAATTAAA TTCCGTTGGA AACGATTTAT 1200 CTAGAAAAAT GGCATTTTTC TCCCGTGACT TTCGTCTTGG ATTTGGCTCA TACGTTGATA 1260 AAACAGTTTC ACCATACATT AGCATCCACC CCGAAAGGAT TCATAATCAA TGCAGTGACT 1320 ACAATTTAGA CTGCATGCCT CCCCATGGAT ACATCCATGT βCTGTCTTTG ACAGAGAACA 1380 TCACTGAGTT TGAGAAAGCA GTTCATAGAC AGAAGATCTC TGGAAACATA GATACACCAG 1440 AAGGAGGTTT TGACGCCATG CTTCAGGCAG CTGTCTGTGA AAGTCATATC GGATGGCGAA 1500
AAGAGGCTAA AAGATTGCTG CTGGTGATGA CAGATCAGAC GTCTCATCTC GCTCTTGATA 1560
GCAAATTGGC AGGCATAGTG GTGCCCAATG ACGGAAACTG TCATCTGAAA AACAACGTCT 1620
ACGTCAAATC GACAACCATG GAACACCCCT CACTAGGCCA ACTTTCAGAG AAATTAATAG 1680
ACAACAACAT TAATGTCATC TTTGCAGTTC AAGGAAAACA ATTTCATTGG TATAAGGATC 1740
TTCTACCCCT CTTGCCAGGC ACCATTGCTG GTGAAATAGA ATCAAAGGCT GCAAACCTCA 1800
ATAATTTGGT AGTGGAAGCC TATCAGAAGC TCATTTCAGA AGTGAAAGTT CAGβTGGAAA 1860
ACCAGGTACA AGGCATCTAT TTTAACATTA CCGCCATCTG TCCAGATGGG TCCAGAAAGC 1920
CAGGCATGGA AGGATGCAGA AACGTGACGA GCAATGATGA AGTTCTTTTC AATGTAACAG 1980
TTACAATGAA AAAATGTGAT GTCACAGGAG GAAAAAACTA TGCAATAATC AAACCTATTG 2040
GTTTTAATGA AACCGCTAAA ATTCATATAC ACAGAAACTG CAGCTGTCAG TGTGAGGACA 2100
ACAGAGGACC TAAAGGAAAG TGTGTAGATG AAACTTTTCT AGATTCCAAG TGTTTCCAGT 2160
GTGATGAGAA TAAATGTCAT TTTGATGAAG ATCAGTTTTC TTCTGAGAGT TGCAAGTCAC 2220
ACAAGGATCA GCCTGTTTGC AGTGGTCGAG GAGTTTGTGT TTGTGGGAAA TGTTCATGTC 2280
ACAAAATTAA GCTTGGAAAA GTGTATGGAA AATACTGTGA AAAGβATGAC TTTTCTTGTC 2340
CATATCACCA TGGAAATCTG TGTGCTGGGC ATGGAGAGTG TGAAGCAGGC AGATGCCAAT 2400
GCTTCAGTGG CTGGGAAGGT GATCGATGCC AGTGCCCTTC AGCAGCAGCC CAGCACTGTG 2460
TCAATTCAAA GGGCCAAGTG TGCAGTGGAA GAGGCACGTG TGTGTGTGGA AGGTGTGAGT 2520
GCACCGATCC CAGGAGCATC GGCCGCTTCT GTGAACACTG CCCCACCTGT TATACAGCCT 2580
GCAAGGAAAA CTGGAATTGT ATGCAATGCC TTCACCCTCA CAATTTGTCT CAGGCTATAC 2640
TTGATCAGTG CAAAACCTCA TGTGCTCTCA TGGAACAACA GCATTATGTC GACCAAACTT 2700
CAGAATGTTT CTCCAGCCCA AGCTACTTGA GAATATTTTT CATCATTTTC ATAGTTACAT 2760
TCTTGATTGG GTTGCTTAAA GTCCTGATCA TTAGACAGGT GATACTACAA TGGAATAGTA 2820
ATAAAATTAA GTCCTCATCA GATTACAGAG TGTCAGCCTC AAAAAAGGAT AAGTTGATTC 2880
TGCAAAGTGT TTGCACAAGA GCAGTCACCT ACCGACGTGA GAAGCCTGAA GAAATAAAAA 2940
TGGATATCAG CAAATTAAAT GCTCATGAAA CTTTCAGGTG CAACTTCTAA AAAAAGATTT 3000
TTAAACACTT AATGGGAAAC TGGAATTGTT AATAATTGCT CCTAAAGATT ATAATTTTAA 3060
AAGTCACAGG AGGAGACAAA TTGCTCACGG TCATGCCAGT TGCTGGTTGT ACACTCGAAC 3120
GAAGACTGAC AAGTATCCTC ATCATGATGT GACTCACATA GCTGCTGACT TTTTCAGAGA 3180
AAAATGTGTC TTACTACTGT TTGAGACTAG TGTCGTTGTA GCACTTTACT GTAATATATA 3240
ACTTATTTAG ATCAGCATAG AATGTAGATC CTCTGAAGAG CACTGATTAC ACTTTACAGG 3300
TACCTGTTAT CCCTACGCTT CCCAGAGAGA ACAATGCTGT GAGAGAGTTT AGCATTGTGT 3360
CACTACAAGG GTACAGTAAT CCCTGCACTG GACATGTGAG GAAAAAAATA ATCTGGCAAG 3420
TATATTCTAA GGTTGCCAAA CACTTCAACA GTTGGTGGTT GAATAGACAA GAACAGCTAG 3480
ATGAATAAAT GATTCGTGTT TCACTCTTTC AAGAGGTGAA CAGATACAAC CTTAATCTTA 3540
AAAGATTATT GCTTTTTAAA GTGTGTAGTT TTATGCATGT GTGTTTATGG TTTGCTTATT 3600
TTTGCAAGAT GGATACTAAT TCCAGCATTC TCTCCTCTTT GCCTTTATGT TTTGTTTTCT 3660
TTTTTACAGG ATAAGTTTAT GTATGTCACA GATGACTGGA TTAATTAAGT GCTAAGTTAC 3720
TACTGCCATA AAAAACTAAT AATACAATGT CACTTTATCA GAATACTAGT TTTAAAAGCT 3780
GAATGTTAA
Seq ID NO: 480 Protein sequence Protein Accession #: NP 002205
11 21 31 41 51
IGPASFLWAA I
MCGSALAFFT A IAFVCLQNDR R WVFSLVLGLG Q IGEDNRCASS N IAASCARCLA 60 LGPECGWCVQ EDFISGGSRS ERCDIVSNLI SKGCSVDSIE YPSVHVIIPT ENEINTQVTP 120 GEVSIQLRPG AEANFMLKVH PLKKYPVDLY YLVDVSASMH NNIEKLNSVG NDLSRKMAFF 180 SRDFRLGFGS YVDKTVSPYI SIHPERIHNQ CSDYNLDCMP PHGYIHVLSL TENITEFEKA 240 VHRQKISGNI DTPEGGFDAM LQAAVCESHI GWRKEAKRLL LVMTDQTSHL ALDSKLAGIV 300 VPNDGNCHLK NNVYVKSTTM EHPSLGQLSE KLIDNNINVI FAVQGKQFHW YKDLLPLLPG 360 TIAGEIESKA ANLNNLWEA YQKLISEVKV QVENQVQGIY FNITAICPDG SRKPGMEGCR 420 NVTSNDEVLF NVTVTMKKCD VTGGKNYAII KPIGFNETAK IHIHRNCSCQ CEDNRGPKGK 480 CVDETFLDSK CFQCDENKCH FDEDQFSSES CKSHKDQPVC SGRGVCVCGK CSCHKIKLGK 540 VYGKYCEKDD FSCPYHHGNL CAGHGECEAG RCQCFSGWEG DRCQCPSAAA QHCVNSKGQV 600 CSGRGTCVCG RCECTDPRSI GRFCEHCPTC YTACKENWNC MQCLHPHNLS QAILDQCKTS 660 CALMEQQHYV DQTSECFSSP SYLRIFFIIF IVTFLIβLLK VLIIRQVILQ WNSNKIKSSS 720 DYRVSASKKD KLILQSVCTR AVTYRREKPE EIKMDISKLN AHETFRCNF
Seq ID NO: 481 DNA sequence
Nucleic Acid Accession #: NM_003318.1
Coding sequence: 1..2574
11 21 31 41
ATGGAATCCG AGGATTTAAG TGGCAGAGAA TTGACAATTG ATTCCATAAT GAACAAAGTG 60
AGAGACATTA AAAATAAGTT TAAAAATGAA GACCTTACTG ATGAACTAAG CTTGAATAAA 120
ATTTCTGCTG ATACTACAGA TAACTCGGGA ACTGTTAACC AAATTATGAT GATGGCAAAC 180
AACCCAGAGG ACTGGTTGAG TTTGTTGCTC AAACTAGAGA AAAACAGTGT TCCGCTAAGT 240
GATGCTCTTT TAAATAAATT GATTGGTCGT TACAGTCAAG CAATTGAAGC GCTTCCCCCA 300
CATAAATATβ GCCAAAATGA GAGTTTTGCT AGAATTCAAG TGAGATTTGC TGAATTAAAA 360
GCTATTCAAG AGCCAGATGA TGCACGTGAC TACTTTCAAA TGGCCAGAGC AAACTGCAAG 420
AAATTTβCTT TTGTTCATAT ATCTTTTGCA CAATTTGAAC TGTCACAAGG TAATGTCAAA 480
AAAAGTAAAC AACTTCTTCA AAAAGCTGTA GAACGTGGAG CAGTACCACT AGAAATGCTG 540
GAAATTGCCC TGCGGAATTT AAACCTCCAA AAAAAGCAGC TGCTTTCAGA GGAGGAAAAG 600
AAGAATTTAT CAGCATCTAC GGTATTAACT GCCCAAGAAT CATTTTCCGG TTCACTTGGG 660
CATTTACAGA ATAGGAACAA CAGTTGTGAT TCCAGAGGAC AGACTACTAA AGCCAGGTTT 720
TTATATGGAG AGAACATGCC ACCACAAGAT GCAGAAATAG GTTACCGGAA TTCATTGAGA 780
CAAACTAACA AAACTAAACA GTCATGCCCA TTTGGAAGAG TCCCAGTTAA CCTTCTAAAT 840
AGCCCAGATT GTGATGTGAA GACAGATGAT TCAGTTGTAC CTTGTTTTAT GAAAAGACAA 900
ACCTCTAGAT CAGAATGCCG AGATTTGGTT GTGCCTGGAT CTAAACCAAG TGGAAATGAT 960
TCCTGTGAAT TAAGAAATTT AAAGTCTGTT CAAAATAGTC ATTTCAAGGA ACCTCTGGTG 1020
TCAGATGAAA AGAGTTCTGA ACTTATTATT ACTGATTCAA TAACCCTGAA GAATAAAACG 1080 GAATCAAGTC TTCTAGCTAA ATTAGAAGAA ACTAAAGAβT ATCAAGAACC AGAGGTTCCA 1140 GAGAGTAACC AGAAACAGTG GCAATCTAAG AGAAAGTCAG AGTGTATTAA CCAGAATCCT 1200 GCTGCATCTT CAAATCACTG GCAGATTCCG GAGTTAGCCC GAAAAGTTAA TACAGAGCAG 1260 AAACATACCA CTTTTGAGCA ACCTGTCTTT TCAGTTTCAA AACAGTCACC ACCAATATCA 1320 ACATCTAAAT GGTTTGACCC AAAATCTATT TGTAAGACAC CAAGCAGCAA TACCTTGGAT 1380 GATTACATGA GCTGTTTTAG AACTCCAGTT GTAAAGAATG ACTTTCCACC TGCTTGTCAG 1440 TTGTCAACAC CTTATGGCCA ACCTGCCTGT TTGCAGCAGC AACAGCATCA AATACTTGCC 1500 ACTCCACTTC AAAATTTACA GGTTTTAGCA TCTTCTTCAG CAAATGAATG CATTTCGGTT 1560 AAAGGAAGAA TTTATTCCAT TTTAAAGCAG ATAGGAAGTG GAGGTTCAAG CAAGGTATTT 1620 CAGGTGTTAA ATGAAAAGAA ACAGATATAT GCTATAAAAT ATGTGAACTT AGAAGAAGCA 1680 GATAACCAAA CTCTTGATAG TTACCGGAAC GAAATAGCTT ATTTGAATAA ACTACAACAA 1740 CACAGTGATA AGATCATCCG ACTTTATGAT TATGAAATCA CGGACCAGTA CATCTACATG 1800 GTAATGGAGT GTGGAAATAT TGATCTTAAT ACTTβGCTTA AAAAGAAAAA ATCCATTGAT 1860 CCATGGGAAC GCAAGAGTTA CTGGAAAAAT ATGTTAGAGG CAGTTCACAC AATCCATCAA 1920 CATGGCATTG TTCACAGTGA TCTTAAACCA GCTAACTTTC TGATAGTTGA TGGAATGCTA 1980 AAGCTAATTG ATTTTGGβAT TGCAAACCAA ATGCAACCAG ATACAACAAG TGTTGTTAAA 2040 GATTCTCAGG TTGGCACAGT TAATTATATG CCACCAGAAG CAATCAAAGA TATGTCTTCC 2100 TCCAGAGAGA ATGβGAAATC TAAGTCAAAG ATAAGCCCCA AAAGTGATGT TTGGTCCTTA 2160 GGATGTATTT TGTACTATAT GACTTACGGG AAAACACCAT TTCAGCAGAT AATTAATCAG 2220 ATTTCTAAAT TACATGCCAT AATTGATCCT AATCATGAAA TTGAATTTCC CGATATTCCA 2280 GAGAAAGATC TTCAAGATGT GTTAAAGTGT TGTTTAAAAA GGGACCCAAA ACAGAGGATA 2340 TCCATTCCTG AGCTCCTGGC TCATCCCTAT GTTCAAATTC AAACTCATCC AGTTAACCAA 2400 ATGGCCAAGG GAACCACTGA AGAAATGAAA TATGTTCTGG GCCAACTTGT TGGTCTGAAT 2460 TCTCCTAACT CCATTTTGAA AGCTGCTAAA ACTTTATATG AACACTATAG TGGTGGTGAA 2520 AGTCATAATT CTTCATCCTC CAAGACTTTT GAAAAAAAAA GGGGAAAAAA ATGA
Seq ID NO: 482 Protein sequence Protein Accession ft: NP_003309.1
11 21 31 41 51
I I I I I
MESEDLSGRE LTIDSIMNKV RDIKNKFKNE DLTDELSLNK ISADTTDNSG TVNQIMMMAN 60 NPEDWLSLLL KLEKNSVPLS DALLNKLIGR YSQAIEALPP DKYGQNESFA RIQVRFAELK 120 AIQEPDDARD YFQMARANCK KFAFVHISFA QFELSQGNVK KSKQLLQKAV ERGAVPLEML 180 EIALRNLNLQ KKQLLSEEEK KNLSASTVLT AQESFSGSLG HLQNRNNSCD SRGQTTKARF 240 LYGENMPPQD AEIGYRNSLR QTNKTKQSCP FGRVPVNLLN SPDCDVKTDD SWPCFMKRQ 300 TSRSECRDLV VPGSKPSGND SCELRNLKSV QNSHFKEPLV SDEKSSELII TDSITLKNKT 360 ESSLLAKLEE TKEYQEPEVP ESNQKQWQSK RKSECINQNP AASSNHWQIP ELARKVNTEQ 420 KHTTFEQPVF SVSKQSPPIS TSKWFDPKSI CKTPSSNTLD DYMSCFRTPV VKNDFPPACQ 480 LSTPYGQPAC FQQQQHQILA TPLQNLQVLA SSSANECISV KGRIYSILKQ IβSGGSSKVF 540 QVLNEKKQIY AIKYVNLEEA DNQTLDSYRN EIAYLNKLQQ HSDKIIRLYD YEITDQYIYM 600 VMECGNIDLN SWLKKKKSID PWERKSYWKN MLEAVHTIHQ HGIVHSDLKP ANFLIVDGML 660 KLIDFGIANQ MQPDTTSWK DSQVGTVNYM PPEAIKDMSS SRENGKSKSK ISPKSDVWSL 720 GCILYYMTYG KTPFQQIINQ ISKLHAIIDP NHEIEFPDIP EKDLQDVLKC CLKRDPKQRI 780 SIPELLAHPY VQIQTHPVNQ MAKGTTEEMK YVLGQLVGLN SPNSILKAAK TLYEHYSGGE 840 SHNSSSSKTF EKKRGKK
Seq ID NO: 483 DNA sequence Nucleic Acid Acceεεion ft: NM_003667.1 Coding εequence: 1..2651
11 21 31 41 51
I I I I I
ATGGACACCT CCCGGCTCGG TGTGCTCCTG TCCTTGCCTG TGCTGCTGCA GCTGGCGACC 60 GGGGGCAGCT CTCCCAGGTC TGGTGTGTTG CTGAGGGGCT GCCCCACACA CTGTCATTGC 120 GAGCCCGACG GCAGGATGTT GCTCAGGGTG GACTGCTCCG ACCTGGGGCT CTCGGAGCTG 180 CCTTCCAACC TCAGCGTCTT CACCTCCTAC CTAGACCTCA GTATGAACAA CATCAGTCAG 240 CTGCTCCCGA ATCCCCTGCC CAGTCTCCGC TTCCTGGAGG AGTTACGTCT TGCGGGAAAC 300 GCTCTGACAT ACATTCCCAA GGGAGCATTC ACTGGCCTTT ACAGTCTTAA AGTTCTTATG 360 CTGCAGAATA ATCAGCTAAG ACACGTACCC ACAGAAGCTC TGCAGAATTT GCGAAGCCTT 420 CAATCCCTGC GTCTGGATGC TAACCACATC AGCTATGTGC CCCCAAGCTG TTTCAGTGGC 480 CTGCATTCCC TGAGGCACCT GTGGCTGGAT GACAATGCGT TAACAGAAAT CCCCGTCCAG 540 GCTTTTAGAA GTTTATCGGC ATTGCAAGCC ATGACCTTGG CCCTGAACAA AATACACCAC 600 ATACCAGACT ATGCCTTTGG AAACCTCTCC AGCTTGGTAG TTCTACATCT CCATAACAAT 660 AGAATCCACT CCCTGGGAAA GAAATGCTTT GATGGGCTCC ACAGCCTAGA GACTTTAGAT 720 TTAAATTACA ATAACCTTGA TGAATTCCCC ACTGCAATTA GGACACTCTC CAACCTTAAA 780 GAACTACATT TCTATGACAA TCCCATCCAA TTTGTTGGGA GATCTGCTTT TCAACATTTA 840 CCTGAACTAA GAACACTGAC TCTGAATGGT GCCTCACAAA TAACTGAATT TCCTGATTTA 900 ACTGGAACTG CAAACCTGGA GAGTCTGACT TTAACTGGAG CACAGATCTC ATCTCTTCCT 960 CAAACCGTCT GCAATCAGTT ACCTAATCTC CAAGTGCTAG ATCTCTCTTA CAACCTATTA 1020 GAAGATTTAC CCAGTTTTTC AGTCTGCCAA AAGCTTCAGA AAATTGACCT AAGACATAAT 1080 GAAATCTACG AAATTAAAGT TGACACTTTC CAGCAGTTGC TTAGCCTCCG ATCGCTGAAT 1140 TTGGCTTGGA ACAAAATTGC TATTATTCAC CCCAATGCAT TTTCCACTTT GCCATCCCTA 1200 ATAAAGCTGG ACCTATCGTC CAACCTCCTG TCGTCTTTTC CTATAACTGG GTTACATGGT 1260 TTAACTCACT TAAAATTAAC AGGAAATCAT GCCTTACAGA GCTTGATATC ATCTGAAAAC 1320 TTTCCAGAAC TCAAGGTTAT AGAAATGCCT TATGCTTACC AGTGCTGTGC ATTTGGAGTG 1380 TGTGAGAATG CCTATAAGAT TTCTAATCAA TGGAATAAAG GTGACAACAG CAGTATGGAC 1440 GACCTTCATA AGAAAGATGC TGGAATGTTT CAGGCTCAAG ATGAACGTGA CCTTGAAGAT 1500 TTCCTGCTTG ACTTTGAGGA AGACCTGAAA GCCCTTCATT CAGTGCAGTG TTCACCTTCC 1560 CCAGGCCCCT TCAAACCCTG TGAACACCTG CTTGATGGCT GGCTGATCAG AATTGGAGTG 1620 TGGACCATAG CAβTTCTGGC ACTTACTTGT AATGCTTTGG TGACTTCAAC AGTTTTCAGA 1680 TCCCCTCTGT ACATTTCCCC CATTAAACTβ TTAATTGGGG TCATCGCAGC AGTGAACATG 1740 CTCACGGGAG TCTCCAGTGC CGTGCTGGCT GGTGTGGATG CGTTCACTTT TGGCAGCTTT 1800 GCACGACATG GTGCCTGGTG GGAGAATGGG GTTGGTTGCC ATGTCATTGG TTTTTTGTCC 1860 ATTTTTGCTT CAGAATCATC TGTTTTCCTG CTTACTCTGG CAGCCCTGGA GCGTGGGTTC 1920 TCTGTGAAAT ATTCTGCAAA ATTTGAAACG AAAGCTCCAT TTTCTAGCCT GAAAGTAATC 1980 ATTTTGCTCT GTGCCCTGCT GGCCTTGACC ATββCCGCAG TTCCCCTGCT GGGTGGCAGC 2040 AAGTATGGCG CCTCCCCTCT CTGCCTGCCT TTGCCTTTTG GGGAGCCCAG CACCATGGGC 2100 TACATGGTCG CTCTCATCTT GCTCAATTCC CTTTGCTTCC TCATGATGAC CATTGCCTAC 2160 ACCAAGCTCT ACTGCAATTT G6ACAAGGGA GACCTGGAGA ATATTTGGGA CTGCTCTATG 2220 GTAAAACACA TTGCCCTGTT GCTCTTCACC AACTGCATCC TAAACTGCCC TGTGGCTTTC 2280 TTGTCCTTCT CCTCTTTAAT AAACCTTACA TTTATCAGTC CTGAAGTAAT TAAGTTTATC 2340 CTTCTGGTGG TAGTCCCACT TCCTGCATGT CTCAATCCCC TTCTCTACAT CTTGTTCAAT 2400 CCTCACTTTA AGGAGGATCT GGTGAGCCTG AGAAAGCAAA CCTACGTCTG GACAAGATCA 2460 AAACACCCAA GCTTGATGTC AATTAACTCT GATGATGTCG AAAAACAGTC CTGTGACTCA 2520 ACTCAAGCCT TGGTAACCTT TACCAGCTCC AGCATCACTT ATGACCTGCC TCCCAGTTCC 2580 GTβCCATCAC CAGCTTATCC AGTGACTGAG AGCTGCCATC TTTCCTCTGT GGCATTTGTC 2640 CCATGTCTTA A
Seq ID NO: 484 Protein εequence Protein Accession #: NP_003658.1
11 21 31 41 51
I I I I I
MDTSRLGVLL SLPVLLQLAT GGSSPRSGVL LRGCPTHCHC EPDGRMLLRV DCSDLGLSEL 60 PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALTYIPKGAF TGLYSLKVLM 120 LQNNQLRHVP TEALQNLRSL QSLRLDANHI SYVPPSCFSG LHSLRHLWLD DNALTEIPVQ 180 AFRSLSALQA MTLALNKIHH IPDYAFGNLS SLWLHLHNN RIHSLGKKCF DGLHSLETLD 240 LNYNNLDEFP TAIRTLSNLK ELHFYDNPIQ FVGRSAFQHL PELRTLTLNG ASQITEFPDL 300 TGTANLESLT LTGAQISSLP QTVCNQLPNL QVLDLSYNLL EDLPSFSVCQ KLQKIDLRHN 360 EIYEIKVDTF QQLLSLRSLN LAWNKIAIIH PNAFSTLPSL IKLDLSSNLL SSFPITGLHG 420 LTHLKLTGNH ALQSLISSEN FPELKVIEMP YAYQCCAFGV CENAYKISNQ WNKGDNSSMD 480 DLHKKDAGMF QAQDERDLED FLLDFEEDLK ALHSVQCSPS PGPFKPCEHL LDGWLIRIGV 540 WTIAVLALTC NALVTSTVFR SPLYISPIKL LIGVIAAVNM LTGVSSAVLA GVDAFTFGSF 600 ARHGAWWENG VGCHVIGFLS IFASESSVFL LTLAALERGF SVKYSAKFET KAPFSSLKVI 660 ILLCALLALT MAAVPLLGGS KYGASPLCLP LPFGEPSTMG YMVALILLNS LCFLMMTIAY 720 TKLYCNLDKG DLENIWDCSM VKHIALLLFT NCILNCPVAF LSFSSLINLT FISPEVIKFI 780 LLVWPLPAC LNPLLYILFN PHFKEDLVSL RKQTYVWTRS KHPSLMSINS DDVEKQSCDS 840 TQALVTFTSS SITYDLPPSS VPSPAYPVTE SCHLSSVAFV PCL
Seq ID NO: 485 DNA sequence
Nucleic Acid Accession #: NM_005756.1
Coding sequence: 73..3117
11 21 31 41 51
AGCCAGCCCG AGGACGCGAG CGGCAGGTGT GCACAGAGGT TCTCCACTTT GTTTTCTGAA 60
CTCGCGGTCA GGATGGTTTT CTCTGTCAGG CAGTGTGGCC ATGTTGGCAG AACTGAAGAA 120
GTTTTACTGA CGTTCAAGAT ATTCCTTGTC ATCATTTGTC TTCATGTCGT TCTGGTAACA 180
TCCCTGGAAG AAGATACTGA TAATTCCAGT TTGTCACCAC CACCTGCTAA ATTATCTGTT 240
GTCAGTTTTG CCCCCTCCTC CAATGAGGTT GAAACAACAA GCCTCAATGA TGTTACTTTA 300
AGCTTACTCC CTTCAAACGA AACAGAAAAA ACTAAAATCA CTATAGTAAA AACCTTCAAT 360
GCTTCAGGCG TCAAACCCCA GAGAAATATC TGCAATTTGT CATCTATTTG CAATGACTCA 420
GCATTTTTTA GAGGTGAGAT CATGTTTCAA TATGATAAAG AAAGCACTGT TCCCCAGAAT 480
CAACATATAA CGAATGGCAC CTTAACTGGA GTCCTGTCTC TAAGTGAATT AAAACGCTCA 540
GAGCTCAACA AAACCCTGCA AACCCTAAGT GAGACTTACT TTATAATGTG TGCTACAGCA 600
GAGGCCCAAA GCACATTAAA TTGTACATTC ACAATAAAAC TGAATAATAC AATGAATGCA 660
TGTGCTGCAA TAGCCGCTTT GGAAAGAGTA AAGATTCGAC CAATGGAACA CTGCTGCTGT 720
TCTGTCAGGA TACCCTGCCC TTCCTCCCCA GAAGAGTTGG GAAAGCTTCA GTGTGACCTG 780
CAGGATCCCA TTGTCTGTCT TGCTGACCAT CCACGTGGCC CACCATTTTC TTCCAGCCAA 840
TCCATCCCAG TGGTGCCTCG GGCCACTGTG CTTTCCCAGG TCCCCAAAGC TACCTCTTTT 900
GCTGAGCCTC CAGATTATTC ACCTGTGACC CACAATGTTC CCTCTCCAAT AGGGGAGATT 960
CAACCCCTTT CACCCCAGCC TTCAGCTCCC ATAGCTTCCA GCCCTGCCAT TGACATGCCC 1020
CCACAGTCTG AAACGATCTC TTCCCCTATG CCCCAAACCC ATGTCTCCGG CACCCCACCT 1080
CCTGTGAAAG CCTCATTTTC CTCTCCCACC GTGTCTGCCC CTGCGAATGT CAACACTACC 1140
AGCGCACCTC CTGTCCAGAC AGACATCGTC AACACCAGCA GTATTTCTGA TCTTGAGAAC 1200
CAAGTGTTGC AGATGGAGAA GGCTCTGTCC TTGGGCAGCC TGGAGCCTAA CCTCGCAGGA 1260
GAAATGATCA ACCAAGTCAG CAGACTCCTT CATTCCCCGC CTGACATGCT GGCCCCTCTG 1320
GCTCAAAGAT TGCTGAAAGT AGTGGATGAC ATTGGCCTAC AGCTGAACTT TTCAAACACG 1380
ACTATAAGTC TAACCTCCCC TTCTTTGGCT CTGGCTGTGA TCAGAGTGAA TGCCAGTAGT 1440
TTCAACACAA CTACCTTTGT GGCCCAAGAC CCTGCAAATC TTCAGGTTTC TCTGGAAACC 1500
CAAGCTCCTG AGAACAGTAT TGGCACAATT ACTCTTCCTT CATCGCTGAT GAATAATTTA 1560
CCAGCTCATG ACATGGAGCT AGCTTCCAGG GTTCAGTTCA ATTTTTTTGA AACACCTGCT 1620
TTGTTTCAGG ATCCTTCCCT GGAGAACCTC TCTCTGATCA GCTACGTCAT ATCATCGAGT 1680
GTTGCAAACC TGACCGTCAG GAACTTGACA AGAAACGTGA CAGTCACATT AAAGCACATC 1740
AACCCGAGCC AGGATGAGTT AACAGTGAGA TGTGTATTTT GGGACTTGGG CAGAAATGGT 1800
GGCAGAGGAG GCTGGTCAGA CAATGGCTGC TCTGTCAAAG ACAGβAGATT GAATGAAACC I860
ATCTGTACCT GTAGCCATCT AACAAGCTTC GGCGTTCTGC TGGACCTATC TAGGACATCT 1920
GTGCTGCCTG CTCAAATGAT GGCTCTGACG TTCATTACAT ATATTGGTTG TGGGCTTTCA 1980
TCAATTTTTC TGTCAGTGAC TCTTGTAACC TACATAGCTT TTGAAAAGAT CCGGAGGGAT 2040
TACCCTTCCA AAATCCTCAT CCAGCTGTGT GCTGCTCTGC TTCTGCTGAA CCTGGTCTTC 2100
CTCCTGGACT CGTGGATTGC TCTGTATAAG ATGCAAGGCC TCTGCATCTC AGTGGCTGTA 2160
TTTCTTCATT ATTTTCTCTT GGTCTCATTC ACATGGATGG GCCTAGAAGC ATTCCATATG 2220
TACCTGGCCC TTGTCAAAGT ATTTAATACT TACATCCGAA AATACATCCT TAAATTCTGC 2280
ATTGTCGGTT GGGGGGTACC AGCTGTGGTT GTGACCATCA TCCTGACTAT ATCCCCAGAT 2340
AACTATGGGC TTGGATCCTA TGGGAAATTC CCCAATGGTT CACCGGATGA CTTCTGCTGG 2400
ATCAACAACA ATGCAGTATT CTACATTACG GTGGTGGGAT ATTTCTGTGT GATATTTTTG 2460
CTGAACGTCA GCATGTTCAT TGTGGTCCTG GTTCAGCTCT GTCGAATTAA AAAGAAGAAG 2520 CAACTGGGAG CCCAGCGAAA AACCAGTATT CAAGACCTCA GGAGTATCGC TGGCCTTACA 2580 TTTTTACTGG GAATAACTTG GGGCTTTGCC TTCTTTGCCT GGGGACCAGT TAACGTGACC 2640 TTCATGTATC TGTTTGCCAT CTTTAATACC TTACAAGGAT TTTTCATATT CATCTTTTAC 2700 TGTGTGGCCA AAGAAAATGT CAGGAAGCAA TGGAGGCGGT ATCTTTGTTG TGGAAAGTTA 2760 CGGCTGGCTG AAAATTCTCA CTGGAβTAAA ACTGCTACTA ATGGTTTAAA GAAGCAGACT 2820 GTAAACCAAG GAGTGTCCAG CTCTTCAAAT TCCTTACAGT CAAGCAGTAA CTCCACTAAC 2880 TCCACCACAC TGCTAGTGAA TAATGATTGC TCAGTACACG CAAGCGGGAA TGβAAATGCT 2940 TCTACAGAGA GGAATGGGGT CTCTTTTAGT GTTCAGAATG GAGATGTβTG CCTTCACGAT 3000 TTCACTGGAA AACAGCACAT GTTTAACGAG AAGGAAGATT CCTGCAATGG GAAAGGCCGT 3060 ATGGCTCTCA GAAGGACTTC AAAGCGGGGA AGCTTACACT TTATTGAGCA AATGTGATTC 3120 CTTTCTTCTA AAATCAAAGC ATGATGCTTG ACAGTGTGAA ATGTCCAATT TTACCTTTTA 3180 CACAATGTGA GATGTATGAA AATCAACTCA TTTTATTCTC GGCAACATCT GGAGAAGCAT 3240 AAGCTAATTA AGGGCGATGA TTATTATTAC AAGAAGAAAC CAAGACATTA CACCATGGTT 3300 TTTAGACATT TCTGATTTGG TTTCTTATCT TTCATTTTAT AAGAAGGTTG GTTTTAAACA 3360 ATACACTAAG AATGACTCCT ATAAAGAAAA CAAAAAAAGG TAGTGAACTT TCAGCTACCT 3420 TTTAAAGAGG CTAAGTTATC TTTGATAACA TCATATAAAG CAACTGTTGA CTTCAGCCTG 3480 TTGGTGAGTT TAGTTGTβCA TGCCTTTGTT GTATATAAGC TAAATTCTAG TGACCCATGT 3540 GTCAAAAATC TTACTTCTAC ATTTTTTTGT ATTTATTTTC TACTGTGTAA ATGTATTCCT 3600 TTGTAGAATC ATGGTTβTTT TGTCTCACGT GATAATTCAG AAAATCCTTG CTCGTTCCGC 3660 AAATCCTAAA GCTCCTTTTG GAGATGATAT AGGATGTGAA ATACAGAAAC CTCAGTGAAA 3720 TCAAGAAATA ATGATCCCAG CCAGACTGAG AAAATGTAAG CAGACAGTGC CACAGTTAGC 3780 TCATACAGTG CCTTTGA6CA AGTTAGGAAA AGATGCCCCC ACTGGGCAGA CACAGCCCTA 3840 TGGGTCATGG TTTGACAAAC AGAGTGAGAG ACCATATTTT AGCCCCACTC ACCCTCTTGG 3900 GTGCACGACC TGTACAGCCA AACACAGCAT CCAATATGAA TACCCATCCC CTGACCGCAT 3960 CCCCAGTAGT CAGATTATAG AATCTGCACC AAGATGTTTA GCTTTATACC TTGGCCACAG 4020 AGAGGGATGA ACTGTCATCC AGACCATGTG TCAGGAAAAT TGTGAACGTA GATGAGGTAC 4080 ATACACTGCC GCTTCTCAAA TCCCCAGAGC CTTTAGGAAC AGGAGAGTAG ACTAGGATTC 4140 CTTCTCTTAA AAAGGTACAT ATATATGGAA AAAAATCATA TTGCCGTTCT TTAAAAGGCA 4200 ACTGCATGGT ACATTGTTGA TTGTTATGAC TGGTACACTC TGGCCCAGCC AGAGCTATAA 4260 TTGTTTTTTA AATGTGTCTT GAAGAATGCA CAGTGACAAG GGGAGTAGCT ATTGGGAACA 4320 GGGAACTGTC CTACACTGCT ATTGTTGCTA CATGTATCGA GCCTTGATTG CTCCTAGTTA 4380 TATACAGGGT CTATCTTGCT TCCTACCTAC ATCTGCTTGA GCAGTGCCTC AAGTACATCC 4440 TTATTAGGAA CATTTCAAAC CCCTTTTAGT TAAGTCTTTC ACTAAGGTTC TCTTGCATAT 4500 ATTTCAAGTβ AATGTTGβAT CTCAGACTAA CCATAGTAAT AATACACATT TCTGTGAGTG 4560 CTGACTTGTC TTTGCAATAT TTCTTTTCTG ATTTATTTAA TTTTCTTGTA TTTATATGTT 4620 AAAATCAAAA ATGTTAAAAT CAATGAAATA AATTTGCAGT TAAGA
Seq ID NO: 486 Protein sequence Protein Accesεion ff: NP 005747.1
11 21 31 41 51
I I I I
MVFSVRQCGH V 1GRTEEVLLT FKIFLVIICL HWLVTSLEE DTDNSSLSPP PAKLSWSFA 60 PSSNEVETTS LNDVTLSLLP SNETGVKPQR NICNLSSICN DSAFFRGEIM FQYDKESTVP 120 QNQHITNGTL TGVLSLSELK RSELNKTLQT LSETYFIMCA TAEAQSTLNC TFTIKLNNTM 180 NACAVIAALE RVKIRPMEHC CCSVRIPCPS SPEELEKLQC DLQDPIVCLA DHPRGPPFSS 240 SQSIPWPRA TVLSQVPKAT SFAEPPDYSP VTHNVPSPIG EIQPLSPQPS APIASSPAID 300 MPPQSETISS PMPQTHVSGT PPPVKASFSS PTVSAPANVN TTSAPPVQTD IVNTSSISDL 360 ENQVLQMEKA LSLGSLEPNL AGEMINQVSR LLHSPPDMLA PLAQRLLKW DDIGLQLNFS 420 NTTISLTSPS LALAVIRVNA SSFNTTTFVA QDPANLQVSL ETQAPENSIβ TITLPSSLMN 480 NLPAHDMELA SRVQFNFFET PALFQDPSLE NLSLISYVIS SSVANLTVRN LTRNVTVTLK 540 HINPSQDELT VRCVFWDLGR NGGRGGWSDN GCSVKDRRLN ETICTCSHLT SFGVLLDLSR 600 TSVLPAQMMA LTFITYIβCβ LSSIFLSVTL VTYIAFEKIR RDYPSKILIQ LCAALLLLNL 660 VFLLDSWIAL YKMQGLCISV AVFLHYFLLV SFTWMGLEAF HMYLALVKVF NTYIRKYILK 720 FCIVGWβVPA VWTIILTIS PDNYGLGSYG KFPNGSPDDF CWINNNAVFY ITWGYFCVI 780 FLLNVSMFIV VLVQLCRIKK KKQLGAQRKT SIQDLRSIAG LTFLLGITWG FAFFAWGPVN 840 VTFMYLFAIF NTLQGFFIFI FYCVAKENVR KQWRRYLCCβ KLRLAENSDW SKTATNGLKK 900 QTVNQGVSSS SNSLQSSSNS TNSTTLLVNN DCSVHASGNG NASTERNGVS FSVQNGDVCL 960 HDFTGKQHMF NEKEDSCNGK GRMALRRTSK RGSLHFIEQM
Seq ID NO: 487 DNA sequence Nucleic Acid Accession ft: Eos sequence Coding sequence: 1..2904
11 21 31 41 51
I I I I
ATGGTTTTCT CTGTCAGGCA GTGTGGCCAT GTTGGCAGAA CTGAAGAAGT TTTACTGACG 60 TTCAAGATAT TCCTTGTCAT CATTTGTCTT CATGTCGTTC TCGTAACATC CCTGGAAGAA 120 GATACTGATA ATTCCAGTTT GTCACCACCA CCTGATGTTA CTTTAAGCTT ACTCCCTTCA 180 AACGAAACAG AAAAAACTAA AATCACTATA GTAAAAACCT TCAATGCTTC AGGCGTCAAA 240 CCCCAGAGAA ATATCTGCAA TTTGTCATCT ATTTGCAATG ACTCAGCATT TTTTAGAGGT 300 GAGATCATGT TTCAATATGA TAAAGAAAGC ACTGTTCCCC AGAATCAACA TATAACGAAT 360 GGCACCTTAA CTGGAGTCCT GTCTCTAAGT GAATTAAACA CATTAAATTG TACATTCACA 420 ATAAAACTGA ATAATACAAT GAATGCATGT GCTGTAATAG CTGCTTTGGA AAGAGTAAAG 480 ATTCGACCAA TGGAACACTG CTGCTGTTCT GTCAGGATAC CCTGCCCTTC CTCCCCAGAA 540 GAGTTGGAAA AGCTTCAGTG TGACCTGCAG GATCCCATTG TCTGTCTTGC TGACCATCCA 600 CGTGGCCCAC CATTTTCTTC CAGCCAATCC ATCCCAGTGG TGCCTCGGGC CACTGTGCTT 660 TCCCAGGTCC CCAAAGCTAC CTCTTTTGCT GAGCCTCCAG ATTATTCACC TGTGACCCAC 720 AATGTTCCCT CTCCAATAGG GGAGATTCAA CCCCTTTCAC CCCAGCCTTC AGCTCCCATA 780 GCTTCCAGCC CTGCCATTGA CATGCCCCCA CAGTCTGAAA CGATCTCTTC CCCTATGCCC 840 CAAACCCATG TCTCCGGCAC CCCACCTCCT GTGAAAGCCT CATTTTCCTC TCCCACCGTG 900 TCTGCCCCTG CGAATGTCAA CACTACCAGC GCACCTCCTG TCCAGACAGA CATCGTCAAC 960 ACCAGCAGTA TTTCTGATCT TGAGAACCAA GTGTTGCAGA TGGAGAAGGC TCTGTCCTTG 1020 GGCAGCCTGG AGCCTAACCT CGCAGGAGAA ATGATCAACC AAGTCAGCAG ACTCCTTCAT 1080 TCCCCGCCTG ACATGCTGGC CCCTCTGGCT CAAAGATTGC TGAAAGTAβT GGATGACATT 1140 GGCCTACAGC TGAACTTTTC AAACACGACT ATAAGTCTAA CCTCCCCTTC TTTGGCTCTG 1200 GCTGTGATCA GAGTGAATGC CAGTAGTTTC AACACAACTA ccTTTβτβGC CCAAGACCCT 1260 GCAAATCTTC AGGTTTCTCT GGAAACCCAA GCTCCTGAGA ACAGTATTGG CACAATTACT 1320 CTTCCTTCAT CGCTGATGAA TAATTTACCA GCTCATGACA TGGAGCTAGC TTCCAGGGTT 1380 CAGTTCAATT TTTTTGAAAC ACCTGCTTTG TTTCAGGATC CTTCCCTGGA GAACCTCTCT 1440 CTGATCAGCT ACGTCATATC ATCGAGTGTT GCAAACCTGA CCGTCAGGAA CTTGACAAGA 1500 AACGTGACAG TCACATTAAA GCACATCAAC CCGAGCCAGG ATGAGTTAAC AGTGAGATGT 1560 GTATTTTGGG ACTTGGGCAG AAATGGTGGC AGAGGAGGCT GGTCAGACAA TG6CT6CTCT 1620 GTCAAAGACA GGAGATTGAA TGAAACCATC TGTACCTGTA GCCATCTAAC AAGCTTCGGC 1680 GTTCTGCTGG ACCTATCTAG GACATCTGTG CTGCCTGCTC AAATGATGGC TCTGACGTTC 1740 ATTACATATA TTGGTTGTGG GCTTTCATCA ATTTTTCTGT CAGTGACTCT TGTAACCTAC 1800 ATAGCTTTTG AAAAGATCCG GAβββATTAC CCTTCCAAAA TCCTCATCCA GCTGTGTGCT 1860 GCTCTGCTTC TGCTGAACCT GGTCTTCCTC CTGGACTCGT GGATTGCTCT GTATAAGATG 1920 CAAGGCCTCT GCATCTCAGT GGCTGTATTT CTTCATTATT TTCTCTTGGT CTCATTCACA 1980 TGGATGβeCC TAGAAβCATT CCATATGTAC CTGGCCCTTG TCAAAGTATT TAATACTTAC 2040 ATCCGAAAAT ACATCCTTAA ATTCTGCATT GTCGGTTGGG GGGTACCAGC TGTGGTTGTG 2100 ACCATCATCC TβACTATATC CCCAGATAAC TATGGGCTTG GATCCTATGG GAAATTCCCC 2160 AATGGTTCAC CGβATβACTT CTGCTGGATC AACAACAATG CAGTATTCTA CATTACGGTG 2220 GTGGGATATT TCTGTGTGAT ATTTTTGCTG AACGTCAGCA TGTTCATTGT GGTCCTGGTT 2280 CAGCTCTGTC GAATTAAAAA GAAGAAGCAA CTGGGAGCCC AGCGAAAAAC CAGTATTCAA 2340 GACCTCAGGA GTATCGCTGG CCTTACATTT TTACTGβGAA TAACTTGGGG CTTTGCCTTC 2400 TTTGCCTGGG GACCAGTTAA CGTGACCTTC ATGTATCTGT TTGCCATCTT TAATACCTTA 2460 CAAGGATTTT TCATATTCAT CTTTTACTGT GTGGCCAAAG AAAATGTCAG GAAGCAATGG 2520 AGGCGGTATC TTTGTTGTGG AAAGTTACGG CTGGCTGAAA ATTCTGACTG GAGTAAAACT 2580 GCTACTAATG GTTTAAAGAA GCAGACTGTA AACCAAGGAG TGTCCAGCTC TTCAAATTCC 2640 TTACAGTCAA GCAGTAACTC CACTAACTCC ACCACACTGC TAGTGAATAA TGATTGCTCA 2700 GTACACGCAA GCGGGAATGG AAATGCTTCT ACAGAGAGGA ATGGGGTCTC TTTTAGTGTT 2760 CAGAATGGAG ATGTGTGCCT TCACGATTTC ACTGGAAAAC AGCACATGTT TAACGAGAAG 2820 GAAGATTCCT GCAATGβGAA AGGCCGTATG GCTCTCAGAA GGACTTCAAA GCGGGGAAGC 2880 TTACACTTTA TTβAGCAAAT GTGA
Seq ID NO: 488 Protein sequence Protein Accession ft: Eos sequence
11 21 31 41 51
MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HWLVTSLEE DTDNSSLSPP PDVTLSLLPS 60 NETEKTKITI VKTFNASGVK PQRNICNLSS ICNDSAFFRG EIMFQYDKES TVPQNQHITN 120 GTLTGVLSLS ELNTLNCTFT IKLNNTMNAC AVIAALERVK IRPMEHCCCS VRIPCPSSPE 180 ELEKLQCDLQ DPIVCLADHP RGPPFSSSQS IPWPRATVL SQVPKATSFA EPPDYSPVTH 240 NVPSPIGEIQ PLSPQPSAPI ASSPAIDMPP QSETISSPMP QTHVSGTPPP VKASFSSPTV 300 SAPANVNTTS APPVQTDIVN TSSISDLENQ VLQMEKALSL GSLEPNLAGE MINQVSRLLH 360 SPPDMLAPLA QRLLKWDDI GLQLNFSNTT ISLTSPSLAL AVIRVNASSF NTTTFVAQDP 420 ANLQVSLETQ APENSIGTIT LPSSLMNNLP AHDMELASRV QFNFFETPAL FQDPSLENLS 480 LISYVISSSV ANLTVRNLTR NVTVTLKHIN PSQDELTVRC VFWDLGRNβG RGGWSDNGCS 540 VKDRRLNETI CTCSHLTSFβ VLLDLSRTSV LPAQMMALTF ITYIGCGLSS IFLSVTLVTY 600 IAFEKIRRDY PSKILIQLCA ALLLLNLVFL LDSWIALYKM QGLCISVAVF LHYFLLVSFT 660 WMGLEAFHMY LALVKVFNTY IRKYILKFCI VGWGVPAVW TIILTISPDN YGLGSYGKFP 720 NGSPDDFCWI NNNAVFYITV VGYFCVIFLL NVSMFIWLV QLCRIKKKKQ LGAQRKTSIQ 780 DLRSIAGLTF LLGITWGFAF FAWGPVNVTF MYLFAIFNTL QGFFIFIFYC VAKENVRKQW 840 RRYLCCGKLR LAENSDWSKT ATNGLKKQTV NQGVSSSSNS LQSSSNSTNS TTLLVNNDCS 900 VHASGNGNAS TERNGVSFSV QNGDVCLHDF TGKQHMFNEK EDSCNGKGRM ALRRTSKRGS 960 LHFIEQM
Seq ID NO: 489 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..2811
11 21 31
ATGGTTTTCT CTGTCAGGCA GTGTGGCCAT GTTGGCAGAA CTGAAGAAGT TTTACTGACG 60
TTCAAGATAT TCCTTGTCAT CATTTGTCTT CATGTCGTTC TGGTAACATC CCTGGAAGAA 120
GATACTGATA ATTCCAGTTT GTCACCACCA CCTGAGGTTG AAACAACAAG CCTCAATGAT 180
GTTACTTTAA GCTTACTCCC TTCAAACGAA ACAGGCGTCA AACCCCAGAG AAATATCTGC 240
AATTTGTCAT CTATTTGCAA TGACTCAGCA TTTTTTAGAG GTGAGATCAT GTTTCAATAT 300
GATAAAGAAA GCACTGTTCC CCAGAATCAA CATATAACGA ATGGCACCTT AACTGGAGTC 360
CTGTCTCTAA GTGAATTAAA ACGCTCAGAG CTCAACAAAA CCCTGCAAAC CCTAAGTGAG 420
ACTTACTTTA TAATGTGTGC TACAGCAGAG GCCCAAAGCA CATTAAATTG TACATTCACA 480
ATAAAACTGA ATAATACAAT GAATGCATGT GCTGTAATAG CTGCTTTβGA AAGAGTAAAG 540
ATTCGACCAA TGGAACACTG CTGCTGTTCT GTCAGGATAC GCTGCCCTTC CTCCCCAGAA 600
GAGTTGGAAA AβCTTCAGTG TGACCTGCAG GATCCCATTG TCTGTCTTGC TGACCATCCA 660
CGTGGCCCAC CATTTTCTTC CAGCCAATCC ATCCCAGTGG TGCCTCGGGC CACTGTGCTT 720
TCCCAGGTCC CCAAAGCTAC CTCTTTTGCT GAGCCTCCAG ATTATTCACC TGTGACCCAC 780
AATGTTCCCT CTCCAATAGG GGAGATTCAA CCCCTTTCAC CCCAGCCTTC AGCTCCCATA 840
GCTTCCAGCC CTGCCATTGA CATGCCCCCA CAGTCTGAAA CGATCTCTTC CCCTATGCCC 900
CAAACCCATG TCTCCGGCAC CCCACCTCCT GTGAAAGCCT CATTTTCCTC TCCCACCGTG 960
TCTGCCCCTG CGAATGTCAA CACTACCAGC GCACCTCCTG TCCAGACAGA CATCGTCAAC 1020
ACCAGCAGTA TTTCTGATCT TGAGAACCAA GTGTTGCA6A TGGAGAAGGC TCTGTCCTTG 1080
GGCAGCCTGG AGCCTAACCT CGCAGGAGAA ATGATCAACC AAGTCAGCAG ACTCCTTCAT 1140
TCCCCGCCTG ACATGCTGGC CCCTCTGGCT CAAAGATTGC TGAAAGTAGT GGATGACATT 1200
GGCCTACAGC TGAACTTTTC AAACACGACT ATAAGTCTAA CCTCCCCTTC TTTGGCTCTG 1260
GCTGTGATCA GAGTGAATGC CAGTAGTTTC AACACAACTA CCTTTGTGGC CCAAGACCCT 1320
GCAAATCTTC AGGTTTCTCT GGAAACCCAA GCTCCTGAGA ACAGTATTGG CACAATTACT 1380 CTTCCTTCAT CGCTGATGAA TAATTTACCA GCTCATGACA TGGAGCTAGC TTCCAGGGTT 1440 CAGTTCAATT TTTTTGAAAC ACCTGCTTTG TTTCAGGATC CTTCCCTGGA GAACCTCTCT 1500 CTGATCA6CT ACGTCATATC ATCGAGTGTT GCAAACCTGA CCGTCAGGAA CTTGACAAGA 1560 AACGTGACAG TCACATTAAA GCACATCAAC CCGAGCCAGG ATGAGTTAAC AGTGAGATGT 1620 GTATTTTGGG ACTTGGGCAG AAATGGTGGC AGAGGAGGCT GGTCAGACAA TGGCTGCTCT 1680 GTCAAAGACA βGAGATTGAA TGAAACCATC TGTACCTGTA GCCATCTAAC AAGCTTCGGC 1740 GTTCTGCTGG ACCTATCTAG GACATCTGTG CTGCCTβCTC AAATGATGGC TCTGACGTTC 1800 ATTACATATA TTGGTTGTGβ GCTTTCATCA ATTTTTCTGT CAGTGACTCT TGTAACCTAC 1860 ATAGCTTTTβ AAAAGATCCG GAGGGATTAC CCTTCCAAAA TCCTCATCCA GCTGTGTGCT 1920 GCTCTGCTTC TGCTGAACCT GGTCTTCCTC CTGGACTCGT GGATTGCTCT GTATAAGATG 1980 CAAGGCCTCT GCATCTCAGT GGCTGTATTT CTTCATTATT TTCTCTTGGT CTCATTCACA 2040 TGGATGGGCC TAGAAGCATT CCATATGTAC CTGGCCCTTG TCAAAGTATT TAATACTTAC 2100 ATCCGAAAAT ACATCCTTAA ATTCTGCATT GTCGGTTGβG GGGTACCAGC TGTGGTTGTG 2160 ACCATCATCC TGACTATATC CCCAGATAAC TATGGGCTTG GATCCTATGG GAAATTCCCC 2220 AATGGTTCAC CGGATGACTT CTGCTGGATC AACAACAATG CAGTATTCTA CATTACGGTG 2280 GTGGGATATT TCTGTGTGAT ATTTTTCCTG AACGTCAGCA TGTTCATTGT GGTCCTGGTT 2340 CAGCTCTGTC GAATTAAAAA GAAGAAGCAA CTGGGAGCCC AGCGAAAAAC CAGTATTCAA 2400 GACCTCAGGA GTATCβCTGG CCTTACATTT TTACTGGGAA TAACTTGGGG CTTTGCCTTC 2460 TTTGCCTGGG GACCAGTTAA CGTGACCTTC ATGTATCTGT TTGCCATCTT TAATACCTTA 2520 CAAGGATTTT TCATATTCAT CTTTTACTGT GTGGCCAAAG AAAATGTCAG βAAGCAATGG 2580 ACGCGGTATC TTTGTTGTGG AAAGTTACGG CTGGCTGAAA ATTCTGGAAA TGCTTCTACA 2640 GAGAGGAATG GGGTCTCTTT TAGTGTTCAG AATGGAGATG TGTGCCTTCA CGATTTCACT 2700 GGAAAACAGC ACATGTTTAA CGAGAAGGAA GATTCCTGCA ATGGGAAAGβ CCGTATGGCT 2760 CTCAGAAGGA CTTCAAAGCG GGGAAGCTTA CACTTTATTG AGCAAATGTG A
Seq ID NO: 490 Protein sequence Protein Accession ff: Eos sequence
11 21 31 41 51
I I I I I
MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HWLVTSLEE DTDNSSLSPP PEVETTSLND 60 VTLSLLPSNE TGVKPQRNIC NLSSICNDSA FFRGEIMFQY DKESTVPQNQ HITNGTLTGV 120 LSLSELKRSE LNKTLQTLSE TYFIMCATAE AQSTLNCTFT IKLNNTMNAC AVIAALERVK 180 IRPMEHCCCS VRIPCPSSPE ELEKLQCDLQ DPIVCLADHP RGPPFSSSQS IPWPRATVL 240 SQVPKATSFA EPPDYSPVTH NVPSPIGEIQ PLSPQPSAPI ASSPAIDMPP QSETISSPMP 300 QTHVSGTPPP VKASFSSPTV SAPANVNTTS APPVQTDIVN TSSISDLENQ VLQMEKALSL 360 GSLEPNLAGE MINQVSRLLH SPPDMLAPLA QRLLKWDDI GLQLNFSNTT ISLTSPSLAL 420 AVIRVNASSF NTTTFVAQDP ANLQVSLETQ APENSIGTIT LPSSLMNNLP AHDMELASRV 480 QFNFFETPAL FQDPSLENLS LISYVISSSV ANLTVRNLTR NVTVTLKHIN PSQDELTVRC 540 VFWDLGRNGG RGGWSDNGCS VKDRRLNETI CTCSHLTSFG VLLDLSRTSV LPAQMMALTF 600 ITYIGCGLSS IFLSVTLVTY IAFEKIRRDY PSKILIQLCA ALLLLNLVFL LDSWIALYKM 660 QGLCISVAVF LHYFLLVSFT WMGLEAFHMY LALVKVFNTY IRKYILKFCI VGWGVPAWV 720 TIILTISPDN YGLGSYGKFP NGSPDDFCWI NNNAVFYITV VGYFCVIFLL NVSMFIWLV 780 QLCRIKKKKQ LGAQRKTSIQ DLRSIAGLTF LLGITWGFAF FAWGPVNVTF MYLFAIFNTL 840 QGFFIFIFYC VAKENVRKQW RRYLCCGKLR LAENSGNAST ERNGVSFSVQ NGDVCLHDFT 900 GKQHMFNEKE DSCNGKGRMA LRRTSKRGSL HFIEQM
Seq ID NO: 491 DNA sequence
Nucleic Acid Accession if: Eos sequence
Coding sequence: 1..3045
11 21 31 41 51
ATGGTTTTCT CTGTCAGβCA GTGTGGCCAT GTTGGCAGAA CTGAAGAAGT TTTACTGACG 60 TTCAAGATAT TCCTTGTCAT CATTTGTCTT CATGTCGTTC TGGTAACATC CCTGGAAGAA 120 GATACTGATA ATTCCAGTTT GTCACCACCA CCTGCTAAAT TATCTGTTGT CAGTTTTGCC 180 CCCTCCTCCA ATGAβGTTGA AACAACAAGC CTCAATGATG TTACTTTAAG CTTACTCCCT 240 TCAAACGAAA CAGAAAAAAC TAAAATCACT ATAGTAAAAA CCTTCAATGC TTCAGGCGTC 300 AAACCCCAGA GAAATATCTG CAATTTGTCA TCTATTTGCA ATGACTCAGC ATTTTTTAGA 360 GGTGAGATCA TGTTTCAATA TGATAAAGAA AGCACTGTTC CCCAGAATCA ACATATAACG 420 AATGGCACCT TAACTGGAGT CCTGTCTCTA AGTGAATTAA AACGCTCAGA GCTCAACAAA 480 ACCCTβCAAA CCCTAAβTGA GACTTACTTT ATAATGTGTG CTACAGCAGA GGCCCAAAGC 540 ACATTAAATT GTACATTCAC AATAAAACTG AATAATACAA TGAATGCATG TGCTGCAATA 600 GCCGCTTTGG AAAGAβTAAA GATTCGACCA ATGGAACACT GCTGCTGTTC TGTCAGGATA 660 CCCTGCCCTT CCTCCCCAGA AGAGTTGGGA AAGCTTCAGT GTGACCTGCA GGATCCCATT 720 GTCTGTCTTG CTGACCATCC ACGTGGCCCA CCATTTTCTT CCAGCCAATC CATCCCAGTG 780 GTGCCTCGGG CCACTGTGCT TTCCCAGGTC CCCAAAGCTA CCTCTTTTGC TGAGCCTCCA 840 GATTATTCAC CTGTGACCCA CAATGTTCCC TCTCCAATAG GGGAβATTCA ACCCCTTTCA 900 CCCCAGCCTT CAGCTCCCAT AGCTTCCAGC CCTGCCATTG ACATGCCCCC ACAGTCTGAA 960 ACGATCTCTT CCCCTATGCC CCAAACCCAT GTCTCCGGCA CCCCACCTCC TGTGAAAGCC 1020 TCATTTTCCT CTCCCACCGT GTCTGCCCCT GCGAATGTCA ACACTACCAβ CGCACCTCCT 1080 GTCCAGACAG ACATCGTCAA CACCAGCAGT ATTTCTGATC TTGAGAAGCA AGTGTTGCAG 1140 ATGGAGAAGG CTCTGTCCTT GGGCAGCCTG GAGCCTAACC TCGCAGGAGA AATGATCAAC 1200 CAAGTCAGCA GACTCCTTCA TTCCCCGCCT GACATGCTGG CCCCTCTGGC TCAAAGATTG 1260 CTGAAAGTAG TGGATGACAT TGGCCTACAG CTGAACTTTT CAAACACGAC TATAAGTCTA 1320 ACCTCCCCTT CTTTGGCTCT GGCTGTGATC AGAGTβAATG CCAGTAGTTT CAACACAACT 1380 ACCTTTGTβG CCCAAGACCC TGCAAATCTT CAGGTTTCTC TGGAAACCCA AGCTCCTGAG 1440 AACAGTATTG GCACAATTAC TCTTCCTTCA TCGCTGATGA ATAATTTACC AGCTCATGAC 1500 ATGGAGCTAG CTTCCAC6GT TCAGTTCAAT TTTTTTGAAA CACCTGCTTT GTTTCAGGAT 1560 CCTTCCCTGG AGAACCTCTC TCTGATCAGC TACGTCATAT CATCGAGTβT TGCAAACCTG 1620 ACCGTCAGGA ACTTGACAAG AAACGTGACA GTCACATTAA AGCACATCAA CCCGAGCCAG 1680 GATGAGTTAA CAGTGAGATG TGTATTTTGG GACTTGGGCA CAAATGGTGG CAGAGGAGGC 1740 TGGTCAGACA ATGGCTGCTC TGTCAAAGAC AGGAGATTGA ATGAAACCAT CTGTACCTGT 1800 AGCCATCTAA CAAGCTTCGG CGTTCTGCTG GACCTATCTA GGACATCTGT GCTGCCTGCT 1860 CAAATGATGG CTCTGACGTT CATTACATAT ATTGGTTGTG GGCTTTCATC AATTTTTCTG 1920 TCAGTGACTC TTGTAACCTA CATAGCTTTT GAAAAGATCC GGAGGGATTA CCCTTCCAAA 1980 ATCCTCATCC AGCTGTGTGC TGCTCTGCTT CTGCTGAACC TGGTCTTCCT CCTGGACTCG 2040 TGGATTGCTC TGTATAAGAT GCAAGGCCTC TGCATCTCAG TGGCTGTATT TCTTCATTAT 2100 TTTCTCTTGG TCTCATTCAC ATGGATGGGC CTAGAAGCAT TCCATATGTA CCTGGCCCTT 2160 GTCAAAGTAT TTAATACTTA CATCCGAAAA TACATCCTTA AATTCTGCAT TGTCGGTTGG 2220 GGGGTACCAG CTGTGGTTGT GACCATCATC CTGACTATAT CCCCAGATAA CTATGGGCTT 2280 GGATCCTATG GGAAATTCCC CAATGGTTCA CCGGATGACT TCTGCTGGAT CAACAACAAT 2340 GCAGTATTCT ACATTACGGT GGTGGGATAT TTCTGTGTGA TATTTTTGCT GAACGTCAGC 2400 ATGTTCATTG TGGTCCTGGT TCAGCTCTGT CGAATTAAAA AGAAGAAGCA ACTGGGAGCC 2460 CAGCGAAAAA CCAGTATTCA AGACCTCAGG AGTATCGCTG GCCTTACATT TTTACTGGGA 2520 ATAACTTGGG GCTTTGCCTT CTTTGCCTGG GGACCAGTTA ACGTGACCTT CATGTATCTG 2580 TTTGCCATCT TTAATACCTT ACAAGGATTT TTCATATTCA TCTTTTACTG TGTGGCCAAA 2640 GAAAATGTCA GGAAGCAATG GAGGCGGTAT CTTTGTTGTG GAAAGTTACG GCTGGCTGAA 2700 AATTCTGACT GGAGTAAAAC TGCTACTAAT GGTTTAAAGA AGCAGACTGT AAACCAAGGA 2760 GTGTCCAGGT CTTCAAATTC CTTACAGTCA AGCAGTAACT CCACTAACTC CACCACACTG 2820 CTAGTGAATA ATGATTGCTC AGTACACGCA AGCGGGAATG GAAATGCTTC TACAGAGAGG 2880 AATGGGGTCT CTTTTAGTGT TCAGAATGGA GATGTGTGCC TTCACGATTT CACTGGAAAA 2940 CAGCACATGT TTAACGAGAA GGAAGATTCC TGCAATGGGA AAGGCCGTAT GGCTCTCAGA 3000 AGGACTTCAA AGCGGGGAAG CTTACACTTT ATTGAGCAAA TGTGA
Seq ID NO: 492 Protein sequence Protein Accesεion ft : Eoε εequence
11 21 31 41 51
MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HWLVTSLEE DTDNSSLSPP PAKLSWSFA 60 PSSNEVETTS LNDVTLSLLP SNETEKTKIT IVKTFNASGV KPQRNICNLS SICNDSAFFR 120 GEIMFQYDKE STVPQNQHIT NGTLTGVLSL SELKRSELNK TLQTLSETYF IMCATAEAQS 180 TLNCTFTIKL NNTMNACAAI AALERVKIRP MEHCCCSVRI PCPSSPEELG KLQCDLQDPI 240 VCLADHPRGP PFSSSQSIPV VPRATVLSQV PKATSFAEPP DYSPVTHNVP SPIGEIQPLS 300 PQPSAPIASS PAIDMPPQSE TISSPMPQTH VSGTPPPVKA SFSSPTVSAP ANVNTTSAPP 360 VQTDIVNTSS ISDLENQVLQ MEKALSLGSL EPNLAGEMIN QVSRLLHSPP DMLAPLAQRL 420 LKWDDIGLQ LNFSNTTISL TSPSLALAVI RVNASSFNTT TFVAQDPANL QVSLETQAPE 480 NSIGTITLPS SLMNNLPAHD MELASRVQFN FFETPALFQD PSLENLSLIS YVISSSVANL 540 TVRNLTRNVT VTLKHINPSQ DELTVRCVFW DLGRNGGRGG WSDNGCSVKD RRLNETICTC 600 SHLTSFGVLL DLSRTSVLPA QMMALTFITY IGCGLSSIFL SVTLVTYIAF EKIRRDYPSK 660 ILIQLCAALL LLNLVFLLDS WIALYKMQGL CISVAVFLHY FLLVSFTWMG LEAFHMYLAL 720 VKVFNTYIRK YILKFCIVGW GVPAVWTII LTISPDNYGL GSYGKFPNGS PDDFCWINNN 780 AVFYITWGY FCVIFLLNVS MFIWLVQLC RIKKKKQLGA QRKTSIQDLR SIAGLTFLLG 840 ITWGFAFFAW GPVNVTFMYL FAIFNTLQGF FIFIFYCVAK ENVRKQWRRY LCCGKLRLAE 900 NSDWSKTATN GLKKQTVNQG VSSSSNSLQS SSNSTNSTTL LVNNDCSVHA SGNGNASTER 960 NGVSFSVQNG DVCLHDFTGK QHMFNEKEDS CNGKGRMALR RTSKRGSLHF IEQM
Seq ID NO: 493 DNA sequence Nucleic Acid Accession if: NM_015507 Coding sequence: 241..1902
11 21 31 41 51
I I I I I
CCGCAGAGGA GCCTCGGCCA GGCTAGCCAG GGCGCCCCCA GCCCCTCCCC AGGCCGCGAG 60 CGCCCCTGCC GCGGTGCCTG GCCTCCCCTC CCAGACTGCA GGGACAGCAC CCGGTAACTG 120 CGAGTGGAGC GGAGβACCCβ AGCGGCTGAG GAGAGAGGAG GCGGCGGCTT AGCTGCTACG 180 GGGTCCGGCC GGCGCCCTCC CGAGGGGGGC TCAβGAGGAG GAAGGAGGAC CCGTβCGAGA 240 ATGCCTCTGC CCTGβAGCCT TGCGCTCCCG CTGCTGCTCT CCTGGGTGGC AGGTGGTTTC 300 GGGAACGCGG CCAGTGCAAG GCATCACGGG TTGTTAGCAT CGGCACGTCA GCCTGGGGTC 360 TGTCACTATG GAACTAAACT GGCCTGCTGC TACGGCTGGA GAAGAAACAG CAAGGGAGTC 420 TGTGAAGCTA CATGCGAACC TGGATβTAAG TTTG6TGAGT GCGTGGGACC AAACAAATGC 480 AGATGCTTTC CAGGATACAC CGGGAAAACC TGCAGTCAAG ATGTβAATGA GTGTGGAATG 540 AAACCCCGGC CATGCCAACA CAβATGTGTG AATACACACG GAAβCTACAA βTGCTTTTGC 600 CTCAGTGGCC ACATGCTCAT GCCAGATGCT ACGTGTGTGA ACTCTAGGAC ATGTGCCATG 660 ATAAACTGTC AGTACAGCTG TGAAGACACA GAAGAAGGGC CACAGTGCCT GTGTCCATCC 720 TCAGGACTCC GCCTGGCCCC AAATGGAAGA GACTGTCTAβ ATATTGATGA ATGTGCCTCT 780 GGTAAAGTCA TCTGTCCCTA CAATCGAAGA TGTGTGAACA CATTTGGAAG CTACTACTGC 840 AAATGTCAGA TTGGTTTCGA ACTGCAATAT ATCAGTβGAC GATATGACTG TATAGATATA 900 AATGAATGTA CTATGGATAG CCATACGTGC AGCCACCATG CCAATTGCTT CAATACCCAA 960 GGGTCCTTCA AGTGTAAATG CAAGCAGGGA TATAAAGGCA ATGGACTTCG GTβTTCTβCT 1020 ATCCCTGAAA ATTCTGTGAA GGAAGTCCTC AGAGCACCTG GTACCATCAA AβACAGAATC 1080 AAGAAGTTGC TTGCTCACAA AAACAGCATG AAAAAGAAGG CAAAAATTAA AAATGTTACC 1140 CCAGAACCCA CCAGGACTCC TACCCCTAAG GTGAACTTGC AGCCCTTCAA CTATGAAGAG 1200 ATAGTTTCCA GAGGCGGGAA CTCTCATGGA GGTAAAAAAG GGAATGAAGA GAAAATGAAA 1260 GAGGGGCTTG AGGATGAGAA AAGAGAAGAG AAAGCCCTGA AGAATGACAT AGAGGAGCGA 1320 AGCCTGCGAG GAGATGTGTT TTTCCCTAAG GTGAATGAAG CAGGTGAATT CGGCCTGATT 1380 CTGGTCCAAA GGAAAGCGCT AACTTCCAAA CTGGAACATA AAGATTTAAA TATCTCββTT 1440 GACTGCAGCT TCAATCATGG GATCTGTGAC TGGAAACAGG ATAβAGAAGA TGATTTTGAC 1500 TGGAATCCTG CTGATCGAGA TAATGCTATT GGCTTCTATA TGGCAGTTCC GGCCTTGGCA 1560 GGTCACAAGA AAGACATTGG CCGATTGAAA CTTCTCCTAC CTGACCTGCA ACCCCAAAGC 1620 AACTTCTGTT TGCTCTTTGA TTACCGGCTG GCCGGAGACA AAGTCGGGAA ACTTCGAGTG 1680 TTTGTGAAAA ACAGTAACAA TGCCCTGGCA TGGGA6AAGA CCACGAGTβA GGATGAAAAG 1740 TGGAAGACAG GGAAAATTCA GTTGTATCAA GGAACTGATG CTACCAAAAG CATCATTTTT 1800 GAAGCAGAAC GTGGCAAQ3G CAAAACCGGC GAAATCGCAG TGGATGβCGT CTTGCTTGTT 1860 TCAGGCTTAT GTCCAGATAG CCTTTTATCT GTGGATGACT GAATGTTACT ATCTTTATAT 1920 TTGACTTTGT ATGTCAGTTC CCTGGTTTTT TTGATATTGC ATCATAGGAC CTCTGGCATT 1980 TTAGAATTAC TAGCTGAAAA ATTGTAATGT ACCAACAGAA ATATTATTGT AAGATGCCTT 2040 TCTTGTATAA GATATGCCAA TATTTGCTTT AAATATCATA TCACTGTATC TTCTCAGTCA 2100 TTTCTGAATC TTTCCACATT ATATTATAAA ATATGGAAAT GTCAGTTTAT CTCCCCTCCT 2160 CAGTATATCT GATTTGTATA AGTAAGTTGA TGAGCTTCTC TCTACAACAT TTCTAGAAAA 2220 TAGAAAAAAA AGCACAGAGA AATGTTTAAC TGTTTGACTC TTATGATACT TCTTGGAAAC 2280 TATGACATCA AAGATAGACT TTTGCCTAAG TGGCTTAGCT GGGTCTTTCA TAGCCAAACT 2340 TGTATATTTA AATTCTTTGT AATAATAATA TCCAAATCAT CAAAAAAAAA AAAAAAAA
Seq ID NO: 494 Protein sequence Protein Accession ft: NP 056322
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MPLPWSLALP LLLSWVAGGF GNAASARHHG LLASARQPGV CHYGTKLACC YGWRRNSKGV 60 CEATCEPGCK FGECVGPNKC RCFPGYTGKT CSQDVNECGM KPRPCQHRCV NTHGSYKCFC 120 LSGHMLMPDA TCVNSRTCAM INCQYSCEDT EEGPQCLCPS SGLRLAPNβR DCLDIDECAS 180 GKVICPYNRR CVNTFGSYYC KCHIGFELQY ISGRYDCIDI NECTMDSHTC SHHANCFNTQ 240 GSFKCKCKQG YKGNGLRCSA IPENSVKEVL RAPGTIKDRI KKLLAHKNSM KKKAKIKNVT 300 PEPTRTPTPK VNLQPFNYEE IVSRGGNSHG GKKGNEEKMK EβLEDEKREE KALKNDIEER 360 SLRGDVFFPK VNEAGEFGLI LVQRKALTSK LEHKDLNISV DCSFNH6ICD WKQDREDDFD 420 WNPADRDNAI GFYMAVPALA GHKKDIGRLK LLLPDLQPQS NFCLLFDYRL AGDKVGKLRV 480 FVKNSNNALA WEKTTSEDEK WKTGKIQLYQ GTDATKSIIF EAERGKGKTG EIAVDGVLLV 540 SGLCPDSLLS VDD
Seq ID NO: 495 DNA sequence Nucleic Acid Accession ft: NM_ Coding sequence: 259.-2379
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GCAGCTCCAG TCCCGβACGC AACCCCGβAβ CCGTCTCAGG TCCCTGGGGG GAAC6GTGGG 60
TTAGACGGGG ACGGGAAGGβ ACAGCGGCCT TCGACCGCCC CCCGAGTAAT TGACCCAGGA 120
CTCATTTTCA GGAAAGCCTG AAAATGAGTA AAATAGTGAA ATGAGGAATT TGAACATTTT 180
ATCTTTGGAT GGGGATCTTC TGAGGATGCA AAGAGTGATT CATCCAAGCC ATGTGGTAAA 240
ATCAGGAATT TGAAGAAAAT GGAGATGTTT ACATTTTTGT TGACGTGTAT TTTTCTACCC 300
CTCCTAAβAG GGCACAGTCT CTTCACCTGT GAACCAATTA CTGTTCCCAG ATGTATGAAA 360
ATGGCCTACA ACATGACGTT TTTCCCTAAT CTβATGGGTC ATTATGACCA GAGTATTGCC 420
GCGGTGGAAA TGGAGCATTT TCTTCCTCTC GCAAATCTGβ AATGTTCACC AAACATTGAA 480
ACTTTCCTCT βCAAAGCATT TGTACCAACC TGCATAGAAC AAATTCATGT GGTTCCACCT 540
TGTCGTAAAC TTTGTGAGAA AGTATATTCT GATTGCAAAA AATTAATTGA CACTTTTGGG 600
ATCCGATGGC CTGAGGAGCT TGAATGTGAC AGATTACAAT ACTGTGATGA GACTGTTCCT 660
GTAACTTTTG ATCCACACAC AGAATTTCTT GGTCCTCAGA AGAAAACAGA ACAAGTCCAA 720
AGAGACATTG βATTTTGGTG TCCAAGGCAT CTTAAGACTT CTGGGGGACA AGGATATAAG 780
TTTCTGGGAA TTGACCAGTG TCCGCCTCCA TGCCCCAACA TβTATTTTAA AAGTGATGAG 840
CTAGAGTTTG CAAAAAGTTT TATTGGAACA GTTTCAATAT TTTGTCTTTG TGCAACTCTG 900
TTCACATTCC TTACTTTTTT AATTGATCTT AGAAGATTCA GATACCCAGA GAGACCAATT 960
ATATATTACT CTGTCTGTTA CAGCATTGTA TCTCTTATGT ACTTCATTGG ATTTTTGCTG 1020
GGCGATAGCA CAGCCTGCAA TAAGGCAGAT GAGAAGCTAG AACTTGGTGA CACTGTTGTC 1080
CTAGGCTCTC AAAATAAGGC TTGCACCβTT TTGTTCATGC TTTTGTATTT TTTCACAATβ 1140
GCTGGCACTG TGTβGTGGGT GATTCTTACC ATTACTTGGT TCTTAGCTGC AGGAAGAAAA 1200
TGGAGTTGTG AAGCCATCGA GCAAAAAGCA GTGTGGTTTC ATGCTGTTGC ATGGGGAACA 1260
CCAGGTTTCC TGACTGTTAT GCTTCTTGCT CTGAACAAAG TTGAAGGAGA CAACATTAGT 1320
GGAGTTTGCT TTGTTGGCCT TTATGACCTG GATGCTTCTC GCTACTTTGT ACTCTTGCCA 1380
CTGTGCCTTT GTGTGTTTGT TGGGCTCTCT CTTCTTTTAG CTGGCATTAT TTCCTTAAAT 1440
CATGTTCGAC AAGTCATACA ACATGATGGC CGGAACCAAG AAAAACTAAA GAAATTTATG 1500
ATTCGAATTG GAGTCTTCAG CGGCTTGTAT CTTGTGCCAT TAGTGACACT TCTCGGATGT 1560
TACGTCTATG AGCAAGTGAA CAβGATTACC TGGGAGATAA CTTGGGTGTC TGATCATTGT 1620
CGTCAGTACC ATATCCCATβ TCCTTATCAG GCAAAAGCAA AAGCTCGACC AGAATTGGCT 1680
TTATTTATGA TAAAATACCT GATGACATTA ATTGTTGGCA TCTCTGCTGT CTTCTGGGTT 1740
GGAAGCAAAA AGACATGCAC AGAATGGGCT GGGTTTTTTA AACGAAATCG CAAGAGAGAT 1800
CCAATCAGTG AAAGTCGAAG AGTACTACAG GAATCATGTG AGTTTTTCTT AAAGCACAAT 1860
TCTAAAGTTA AACACAAAAA GAAGCACTAT AAACCAAGTT CACACAAGCT GAAGGTCATT 1920
TCCAAATCCA TGGGAACCAG CACAββAGCT ACAGCAAATC ATGGCACTTC TGCAGTAGCA 1980
ATTACTAβCC ATβATTACCT AGGACAAGAA ACTTTGACAG AAATCCAAAC CTCACCAGAA 2040
ACATCAATβA GAGAGGTGAA AGCGGACGGA GCTAGCACCC CCAGGTTAAG AGAACAGGAC 2100
TGTGGTGAAC CTGCCTCGCC AGCAGCATCC ATCTCCAGAC TCTCTGGGGA ACAGβTCGAC 2160
GGGAAGGGCC AGGCAGβCAβ TGTATCTGAA AGTβCGCββA GTGAAGβAAG GATTAGTCCA 2220
AAβAGTGATA TTACTGACAC TGGCCTGGCA CAGAGCAACA ATTTGCAGGT CCCCACTTCT 2280
TCAGAACCAA GCAGCCTCAA AGGTTCCACA TCTCTGCTTG TTCACCCAGT TTCAGGAGTG 2340
AGAAAAGAGC AGGGAGGTGG TTGTCATTCA GATACTTGAA GAACATTTTC TCTCGTTACT 2400
CAGAAGCAAA TTTGTGTTAC ACTGGAAGTG ACCTATGCAC TGTTTTGTAA GAATCACTGT 2460
TACGTTCTTC TTTTGCACTT AAAGTTGCAT TGCCTACTGT TATACTGGAA AAAATAGAGT 2520
TCAAGAATAA TATGACTCAT TTCACACAAA GGTTAATβAC AAGAATATAC CTGAAAACAG 2580
AAATGTGCAG GTTAATAATA TTTTTTTAAT AGTGTGGGAG GACAGAGTTA GAGGAATCTT 2640
CCTTTTCTAT TTATGAAGAT TCTACTCTTG GTAAGAGTAT TTTAAGATGT ACTATβCTAT 2700
TTTACCTTTT TGATATAAAA TCAAGATATT TCTTTGCTGA AGTATTTAAA TCTTATCCTT 2760
GTATCTTTTT ATACATATTT GAAAATAAβC TTATATGTAT TTGAACTTTT TTβAAATCCT 2820
ATTCAAGTAT TTTTATCATG CTATTGTβAT ATTTTAGCAC TTTGGTAGCT TTTACACTGA 2880
ATTTCTAAGA AAATTGTAAA ATAGTCTTCT TTTATACTGT AAAAAAAGAT ATACCAAAAA 2940
GTCTTATAAT AGGAATTTAA CTTTAAAAAG CCACTTATTG ATACCTTACC ATCTAAAATG 3000
TGTGATTTTT ATAGTCTCGT TTTAGGAATT TCACAGATCT AAATTATGTA ACTGAAATAA 3060
GGTβCTTACT CAAAGAGTGT CCACTATTGA TTGTATTATG CTGCTCACTG ATCCTTCTGC 3120
ATATTTAAAA TAAAATGTCC TAAAGGGTTA GTAGACAAAA TGTTAGTCTT TTGTATATTA 3180
GGCCAAGTGC AATTGACTTC CCTTTTTTAA TGTTTCATGA CCACCCATTG ATTGTATTAT 3240 AACCACTTAC AGTTGCTTAT ATTTTTTGTT TTAACTTTTG TTTCTTAACA TTTAGAATAT 3300 TACATTTTGT ATTATACAGT ACCTTTCTCA GACATTTTGT AG
Seq ID NO: 496 Protein sequence Protein Accession ft: NP_003497.1
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MEMFTFLLTC IFLPLLRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QSIAAVEMEH 60 0 FLPLANLECS PNIETFLCKA FVPTCIEQIH WPPCRKLCE KVYSDCKKLI DTFGIRWPEE 120
LECDRLQYCD ETVPVTFDPH TEFLGPQKKT EQVQRDIGFW CPRHLKTSGG QGYKFLGIDQ 180
CAPPCPNMYF KSDELEFAKS FIGTVSIFCL CATLFTFLTF LIDVRRFRYP ERPI IYYSVC 240
YSIVSLMYFI GFLLGDSTAC NKADEKLELG DTWLGSQNK ACTVLFMLLY FFTMAGTVWW 300
VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGTPGFLTV MLLALNKVEG DNISGVCFVG 360 5 LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF 420
SGLYLVPLVT LLGCYVYEQV NRITWEITWV SDHCRQYHIP CPYQAKAKAR PELALFMIKY 480
LMTLIVGISA VFWVGSKKTC TEWAGFFKRN RKRDPISESR RVLQESCEFF LKHNSKVKHK 540
KKHYKPSSHK LKVISKSMGT STGATANHGT SAVAITSHDY LGQETLTEIQ TSPETSMREV 600
KADGASTPRL REQDCGEPAS PAASISRLSG EQVDGKGQAG SVSESARSEβ RISPKSDITD 660 0 TGLAQSNNLQ VPSSSEPSSL KGSTSLLVHP VSGVRKEQGG GCHSDT
Seq ID NO : 497 DNA sequence Nucleic Acid Accession # : NM_005046 Coding sequence : 16 . . 77 5
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GβATTTCCGG GCTCCATGGC AAGATCCCTT CTCCTGCCCC TGCAGATCCT ACTGCTATCC 60
TTAGCCTTGG AAACTGCAGG AGAAGAAGCC CAGGGTGACA AGATTATTGA TGGCGCCCCA 120 0 TGTGCAAGAG GCTCCCACCC ATGGCAGGTG GCCCTGCTCA GTGβCAATCA βCTCCACTGC 180
GGAGGCGTCC TGGTCAATGA GCβCTGGGTG CTCACTGCCG CCCACTGCAA GATβAATGAG 240
TACACCGTGC ACCTGGGCAG TGATACGCTG GGCGACAGGA GAGCTCAGAG GATCAAGβCC 300
TCGAAGTCAT TCCGCCACCC CGGCTACTCC ACACAβACCC ATGTTAATGA CCTCATGCTC 360
GTGAAβCTCA ATAGCCAGGC CAGGCTGTCA TCCATGGTGA AGAAAGTCAG GCTGCCCTCC 420 5 CGCTβCGAAC CCCCTGGAAC CACCTGTACT GTCTCCGGCT GGGGCACTAC CACβAβCCCA 480
GATGTGACCT TTCCCTCTGA CCTCATGTGC GTGGATβTCA AGCTCATCTC CCCCCAGGAC 540
TGCACGAAGG TTTACAAGGA CTTACTGGAA AATTCCATGC TGTGCβCTGG CATCCCCGAC 600
TCCAAGAAAA ACGCCTGCAA TGGTGACTCA GGGGGACCGT TGGTGTGCAG AGGTACCCTG 660
CAAGGTCTGG TGTCCTGGGG AACTTTCCCT TGCGGCCAAC CCAATβACCC AGGAGTCTAC 720 0 ACTCAAGTGT GCAAβTTCAC CAAGTGGATA AATGACACCA TGAAAAAGCA TCGCTAACGC 780
CACACTGAGT TAATTAACTG TGTGCTTCCA ACAGAAAATG CACAGGAGTG AGGACGCCβA 840
TGACCTATGA AGTCAAATTT GACTTTACCT TTCCTCAAAG ATATATTTAA ACCTCATGCC 900
CTGTTGATAA ACCAATCAAA TTGGTAAAGA CCTAAAACCA AAACAAATAA AGAAACACAA 960 AACCCTCAA 5
Seq ID NO : 498 Protein sequence Protein Accession ft : NP 005037
_ _ 1 11 21 31 41 51 0 I I l i i i
MARSLLLPLQ ILLLSLALET AGEEAQGDKI IDGAPCARβS HPWQVALLSβ NQLHCCGVLV 60
NERWVLTAAH CKMNEYTVHL GSDTLGDRRA QRIKASKSFR HPGYSTQTHV NDLMLVKLNS 120
QARLSSMVKK VRLPSRCEPP GTTCTVSGWG TTTSPDVTFP SDLMCVDVKL ISPQDCTKVY 180
KDLLENSMLC AGIPDSKKNA CNGDSGGPLV CRGTLQGLVS WGTFPCGQPN DPGVYTQVCK 240 5 FTKWINDTMK KHR
Seq ID NO: 499 DNA sequence Nucleic Acid Accession ft: NM_007196 Coding sequence: 182..962
60
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GTTCCCAGAA GCTCCCCAGG CTCTAGTGCA GGAGGAGAAG GAGGAGGAGC AGGAGGTGGA 60
GATTCCCAGT TAAAAGGCTC CAGAATCGTG TACCAGGCAG AGAACTGAAG TACTGGGGCC 120
65 TCCTCCACTG GGTCCGAATC AGTAGGTβAC CCCGCCCCTG GATTCTGGAA GACCTCACCA 180
TGGGACGCCC CCGACCTCGT GCGGCCAAGA CGTGGATGTT CCTGCTCTTG CTGGGGGGAG 240
CCTGGGCACG ACACTCCAGβ GCACAGGAGG ACAAGGTGCT GGGGGGTCAT GAGTGCCAAC 300
CCCATTCGCA GCCTTGGCAG GCGGCCTTGT TCCAGGGCCA GCAACTACTC TGTGGCGGTG 360
TCCTTGTAGG TGGCAACTGG GTCCTTACAG CTGCCCACTG TAAAAAACCG AAATACACAG 420
70 TACGCCTGGG AGACCACAGC CTACAGAATA AAGATGGCCC AGAGCAAGAA ATACCTGTGG 480
TTCAGTCCAT CCCACACCCC TGCTACAACA GCAGCGATGT GGAGGACCAC AACCAT6ATC 540
TGATGCTTCT TCAACTGCGT GACCAGGCAT CCCTGGGGTC CAAAGTGAAG CCCATCAGCC 600
TGβCAGATCA TTGCACCCAG CCTGGCCAGA AGTGCACCGT CTCAGGCTGG GGCACTGTCA 660
CCAGTCCCCG AGAGAATTTT CCTGACACTC TCAACTGTGC AGAAGTAAAA ATCTTTCCCC 720
75 AGAAGAAGTG TGAGGATGCT TACCCGGGGC AGATCACAGA TGGCATGGTC TGTGCAGGCA 780 βCAβCAAAGG GGCTGACACG TGCCAGGGCG ATTCTGGAGG CCCCCTGGTG TGTGATGGTG 840
CACTCCAGGG CATCACATCC TGGGGCTCAG ACCCCTGTGβ GAGGTCCGAC AAACCTGGCG 900
TCTATACCAA CATCTGCCGC TACCTGGACT GGATCAAGAA GATCATAGGC AGCAAGGβCT 960 GATTCTAGGA TAAGCACTAG ATCTCCCTTA ATAAACTCAC AACTCTC
80
Seq ID NO : 500 Protein sequence Protein Accession ft : NP_009127
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MGRPRPRAAK TWMFLLLLGG AWAGHSRAQE DKVLGGHECQ PHSQPWQAAL FQGQQLLCGG 60
VLVGGNWVLT AAHCKKPKYT VRLGDHSLQN KDGPEQEIPV VQSIPHPCYN SSDVEDHNHD 120
LMLLQLRDQA SLGSKVKPIS LADHCTQPGQ KCTVSGWGTV TSPRENFPDT LNCAEVKIFP 180
QKKCEDAYPG QITDGMVCAG SSKGADTCQG DSGGPLVCDG ALQGITSWGS DPCGRSDKPG 240 VYTNICRYLD WIKKIIGSKG
Seq ID NO: 501 DNA sequence Nucleic Acid Accession ft: NM_006103 Coding sequence: 29..406
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CACCTGCACC CCGCCCGGGC ATAGCACCAT GCCTGCTTGT CGCCTAGGCC CGCTAGCCGC 60
CGCCCTCCTC CTCAGCCTGC TβCTGTTCGG CTTCACCCTA GTCTCAGGCA CAGGAGCAGA 120
GAAGACTCGC GTGTGCCCCG AβCTCCAGGC TGACCAGAAC TGCACGCAAG AGTGCGTCTC 180
GGACAGCGAA TGCGCCGACA ACCTCAAGTG CTGCAGCGCG GGCTGTGCCA CCTTCTGCCT 240
TCTCTGCCCA AATGATAAGβ AββGTTCCTG CCCCCAGGTG AACATTAACT TTCCCCAGCT 300
CGGCCTCTGT CGGGACCAGT GCCAGGTGGA CAGCCAGTGT CCTGGCCAGA TGAAATGCTG 360
CCGCAATGGC TGTβββAAGG TGTCCTGTβT CACTCCCAAT TTCTGAGGTC CAGCCACCAC 420
CAGGCTGAGC AGTGAβGAGA GAAAGTTTCT GCCTGGCCCT GCATCTGGTT CCAGCCCACC 480
TβCCCTCCCC TTTTTCGGGA CTCTGTATTC CCTCTTGGGC TGACCACAGC TTCTCCCTTT 540 CCCAACCAAT AAAGTAACCA CTTTCAGCAA AAAAAAAAAA AAAA
Seq ID NO: 502 Protein sequence Protein Accession ft: NP_006094
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MPACRLGPLA AALLLSLLLF GFTLVSGTGA EKTGVCPELQ ADQNCTQECV SDSECADNLK 60 CCSAGCATFC LLCPNDKEGS CPQVNINFPQ LGLCRDQCQV DSQCPGQMKC CRNGCGKVSC 120 VTPNF
Seq ID NO: 503 DNA sequence Nucleic Acid Accesεion # : NM 002407
Coding εequence : 65. .352
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CCTCCACAGC AACTTCCTTG ATCCCTGCCA CGCACGACTG AACACAGACA GCAGCCGCCT 60
CGCCATGAAβ CTGCTGATGβ TCCTCATGCT GGCGGCCCTC CTCCTGCACT GCTATGCAGA 120
TTCTGGCTGC AAACTCCTGG AGβACATGGT TGAAAAGACC ATCAATTCCG ACATATCTAT 180
ACCTGAATAC AAAGAGCTTC TTCAAGAGTT CATAGACAGT GATGCCGCTG CAGAGGCTAT 240
GGGGAAATTC AAGCAGTGTT TCCTCAACCA GTCACATAβA ACTCTGAAAA ACTTTGGACT 300
GATGATGCAT ACAGTGTACG ACAGCATTTG GTGTAATATG AAGAGTAATT AACTTTACCC 360
AAGGCGTTTG GCTCAGAGGG CTACAGACTA TGGCCAGAAC TCATCTGTTG ATTGCTAGAA 420
ACCACTTTTC TTTCTTGTGT TGTCTTTTTA TGTGGAAACT GCTAGACAAC TβTTGAAACC 480 TCAAATTCAT TTCCATTTCA ATAACTAACT GCAAATC
Seq ID NO: 504 Protein sequence Protein Accesεion #: NP_002398
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M IKLLMVLMLA AILLLHCYADS GICKLLEDMVE KITINSDISIP EIYKELLQEFI DISDAAAEAMG 60 KFKQCFLNQS HRTLKNFGLM MHTVYDSIWC NMKSN
Seq ID NO: 505 DNA sequence
Nucleic Acid Accession #: NM_014791.1
Coding sequence: 171..2126
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T ITGGCGGGCG GIAAGCGGCCA CIAACCCGGCG AITCGAAAAGA TITCTTAGGAA CIGCCGTACCA 60
GCCGCGTCTC TCAGGACAGC AGGCCCCTGT CCTTCTGTCG GGCGCCGCTC AGCCGTGCCC 120
TCCGCCCCTC AGGTTCTTTT TCTAATTCCA AATAAACTTG CAAGAGGACT ATGAAAGATT 180
ATGATGAACT TCTCAAATAT TATGAATTAC ATGAAACTAT TGGGACAGGT GGCTTTGCAA 240
ACβTCAAACT TGCCTGCCAT ATCCTTACTG GAGAGATGGT AGCTATAAAA ATCATGGATA 300
AAAACACACT AGGGAGTGAT TTGCCCCGGA TCAAAACGGA GATTGAGGCC TTGAAGAACC 360
TGAGACATCA GCATATATGT CAACTCTACC ATGTGCTAGA GACAGCCAAC AAAATATTCA 420
TGGTTCTTGA GTACTGCCCT GGAGβAβAβC TGTTTGACTA TATAATTTCC CAGGATCGCC 480
TGTCAGAAGA GGAGACCCGG GTTGTCTTCC GTCAGATAGT ATCTβCTGTT GCTTATGTGC 540
ACAGCCAGGG CTATGCTCAC AGGGACCTCA AGCCAGAAAA TTTGCTCTTT GATGAATATC 600
ATAAATTAAA GCTGATTβAC TTTββTCTCT GTGCAAAACC CAAGβGTAAC AAGGATTACC 660
ATCTACAGAC ATGCTGTGGG AGTCTGGCTT ATGCAGCACC TGAGTTAATA CAAG6CAAAT 720
CATATCTTGG ATCAGAGGCA GATGTTTGGA GCATGGGCAT ACTGTTATAT GTTCTTATGT 780
GTGGATTTCT ACCATTTGAT GATGATAATG TAATGGCTTT ATACAAGAA6 ATTATGAGAG 840
GAAAATATGA TGTTCCCAAG TGGCTCTCTC CCAGTAGCAT TCTGCTTCTT CAACAAATGC 900
TGCAGGTGGA CCCAAAGAAA CGGATTTCTA TGAAAAATCT ATTGAACCAT CCCTGGATCA 960
TGCAAGATTA CAACTATCCT GTTGAGTGGC AAAGCAAGAA TCCTTTTATT CACCTCGATG 1020
ATGATTGCβT AACACAACTT TCTGTACATC ACAGAAACAA CAGGCAAACA ATGGAGGATT 1080
TAATTTCACT GTGGCAGTAT GATCACCTCA CGGCTACCTA TCTTCTGCTT CTAGCCAAGA 1140
AGGCTCGGGG AAAACCAGTT CGTTTAAGGC TTTCTTCTTT CTCCTGTGGA CAAGCCAGTG 1200
CTACCCCATT CACAGACATC AAGTCAAATA ATTGGAGTCT GGAAGATGTG ACCGCAAGTG 1260 ATAAAAATTA TGTGGCGGGA TTAATAGACT ATGATTGGTG TGAAGATGAT TTATCAACAG 1320 GTGCTGCTAC TCCCCGAACA TCACAGTTTA CCAAGTACTG GACAGAATCA AATGGGGTGG 1380 AATCTAAATC ATTAACTCCA GCCTTATGCA GAACACCTGC AAATAAATTA AAβAACAAAβ 1440 AAAATGTATA TACTCCTAAG TCTGCTGTAA AGAATGAAGA GTACTTTATG TTTCCTGAGC 1500 CAAAGACTCC AGTTAATAAG AACCAGCATA AGAGAGAAAT ACTCACTACG CCAAATCGTT 1560 ACACTACACC CTCAAAAGCT AGAAACCAGT GCCTGAAAGA AACTCCAATT AAAATACCAG 1620 TAAATTCAAC AGGAACAGAC AAGTTAATGA CAGGTGTCAT TAGCCCTGAG AGGCGGTGCC 1680 GCTCAGTGGA ATTGGATCTC AACCAAGCAC ATATGGAGGA GACTCCAAAA AGAAAGGGAG 1740 CCAAAGTGTT TGGGAGCCTT GAAAGGGGGT TGGATAAGGT TATCACTGTG CTCACCAGGA 1800 GCAAAAGGAA GGβTTCTβCC AGAGACGGGC CCAGAAGACT AAAGCTTCAC TATAATGTGA 1860 CTACAACTAG ATTAβTGAAT CCAGATCAAC TGTTGAATGA AATAATGTCT ATTCTTCCAA 1920 AGAAGCATGT TGACTTTGTA CAAAAβGGTT ATACACTGAA GTGTCAAACA CAGTCAGATT 1980 TTGββAAAβT GACAATGCAA TTTGAATTAG AAGTGTGCCA GCTTCAAAAA CCCGATGTGG 2040 TGGβTATCAG GAGGCAGCGβ CTTAAGGGCG ATGCCTGGβT TTACAAAAGA TTAGTGGAAG 2100 ACATCCTATC TAGCTGCAAG GTATAATTGA TGGATTCTTC CATCCTGCCG GATGAGTβTG 2160 GGTGTGATAC AGCCTACATA AAGACTGTTA TGATCGGTTT GATTTTAAAG TTCATTGGAA 2220 CTACCAACTT GTTTCTAAAG AGCTATCTTA AGACCAATAT CTCTTTGTTT TTAAACAAAA 2280 GATATTATTT TGTGTATGAA TCTAAATCAA GCCCATCTGT CATTATGTTA CTGTCTTTTT 2340 TAATCATGTG GTTTTGTATA TTAATAATTβ TTGACTTTCT TAGATTCACT TCCATATGTG 2400 AATGTAAGCT CTTAACTATG TCTCTTTGTA ATGTGTAATT TCTTTCTGAA ATAAAACCAT 2460 TTGTGAATAT
Seq ID NO: 506 Protein sequence Protein Accession #: NP 055606.1
11 21 31 41 51
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MKDYDELLKY YELHETIGTG GFAKVKLACH ILTGEMVAIK IMDKNTLGSD LPRIKTEIEA 60 LKNLRHQHIC QLYHVLETAN KIFMVLEYCP G6ELFDYIIS QDRLSEEETR WFRQIVSAV 120 AYVHSQGYAH RDLKPENLLF DEYHKLKLID FGLCAKPKGN KDYHLQTCCG SLAYAAPELI 180 QGKSYLGSEA DVWSMGILLY VLMCGFLPFD DDNVMALYKK IMRGKYDVPK WLSPSSILLL 240 QQMLQVDPKK RISMKNLLNH PWIMQDYNYP VEWQSKNPFI HLDDDCVTEL SVHHRNNRQT 300 MEDLISLWQY DHLTATYLLL LAKKARGKPV RLRLSSFSCG QASATPFTDI KSNNWSLEDV 360 TASDKNYVAG LIDYDWCEDD LSTGAATPRT SQFTKYWTES NGVESKSLTP ALCRTPANKL 420 KNKENVYTPK SAVKNEEYFM FPEPKTPVNK NQHKREILTT PNRYTTPSKA RNQCLKETPI 480 KIPVNSTGTD KLMTGVISPE RRCRSVELDL NQAHMEETPK RKGAKVFGSL ERGLDKVITV 540 LTRSKRKGSA RDGPRRLKLH YNVTTTRLVN PDQLLNEIMS ILPKKHVDFV QKβYTLKCQT 600 QSDFGKVTMQ FELEVCQLQK PDWGIRRQR LKGDAWVYKR LVEDILSSCK V
Seq ID NO: 507 DNA sequence Nucleic Acid Accession ft: NM_000582 Coding sequence: 88..990
11 21 31 41 51
GCAβAGCACA GCATCGTCGG GACCAGACTC GTCTCAGGCC AGTTGCAGCC TTCTCAGCCA 60
AACGCCGACC AAGGAAAACT CACTACCATG AGAATTGCAG TGATTTGCTT TTGCCTCCTA 120 βGCATCACCT GTGCCATACC AGTTAAACAG GCTGATTCTG GAAGTTCTGA GGAAAAGCAG 180
CTTTACAACA AATACCCAGA TGCTGTGβCC ACATGGCTAA ACCCTGACCC ATCTCAGAAG 240
CAGAATCTCC TAGCCCCACA GACCCTTCCA AGTAAGTCCA ACGAAAGCCA TGACCACATG 300
GATGATATGG ATGATβAAGA TGATβATGAC CATGTGGACA GCCAGGACTC CATTGACTCG 360
AACGACTCTG ATGATGTAGA TGACACTGAT GATTCTCACC AGTCTGATGA GTCTCACCAT 420
TCTGATGAAT CTGATGAACT GGTCACTGAT TTTCCCACGG ACCTGCCAGC AACCGAAGTT 480
TTCACTCCAG TTGTCCCCAC AGTAGACACA TATGATGGCC GAGGTGATAG TGTGGTTTAT 540
GGACTGAGβT CAAAATCTAA GAAGTTTCGC AGACCTGACA TCCAGTACCC TGATGCTACA 600
GACGAGGACA TCACCTCACA CATGGAAAGC GAGGAGTTGA ATGGTGCATA CAAGGCCATC 660
CCCGTTGCCC AGβACCTGAA CGCCCCTTCT GATTGGGACA GCC6TGGGAA βGACAGTTAT 720
GAAACGAGTC AGCTGGATGA CCAGAGTGCT GAAACCCACA GCCACAAGCA GTCCAGATTA 780
TATAAGCGGA AAGCCAATGA TGAGAGCAAT GAGCATTCCG ATGTGATTGA TAGTCAGGAA 840
CTTTCCAAAβ TCAGCCGTGA ATTCCACAGC CATGAATTTC ACAGCCATGA AGATATGCTG 900
GTTGTAGACC CCAAAAGTAA GGAAGAAGAT AAACACCTGA AATTTCGTAT TTCTCATGAA 960
TTAGATAGTG CATCTTCTGA GGTCAATTAA AAGGAGAAAA AATACAATTT CTCACTTTGC 1020
ATTTAGTCAA AAGAAAAAAT GCTTTATAGC AAAATGAAAG AGAACATGAA ATGCTTCTTT 1080
CTCAGTTTAT TGGTTGAATG TGTATCTATT TGAGTCTGGA AATAACTAAT GTGTTTGATA 1140
ATTAGTTTAG TTTGTGGCTT CATGGAAACT CCCTGTAAAC TAAAAGCTTC AGGGTTATGT 1200
CTATGTTCAT TCTATAGAAG AAATGCAAAC TATCACTGTA TTTTAATATT TGTTATTCTC 1260
TCATGAATAG AAATTTATGT AGAAGCAAAC AAAATACTTT TACCCACTTA AAAAGAGAAT 1320
ATAACATTTT ATGTCACTAT AATCTTTTGT TTTTTAAGTT AGTGTATATT TTGTTGTGAT 1380
TATCTTTTTG TGβTGTGAAT AAATCTTTTA TCTTGAATGT AATAAGAATT TGGTGGTGTC 1440
AATTGCTTAT TTGTTTTCCC ACGGTTGTCC AGCAATTAAT AAAACATAAC CTTTTTTACT 1500
GCCTAAAAAA AAAAAAAAAA AAAA
Seq ID NO: 508 Prote:in sequence
Protein Accession it: NP_000573
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1 1 | 1 | 1 I 1 | 1 | 1 MRIAVICFCL LGITCAIPVK QADSGSSEEK QLYNKYPDAV ATWLNPDPSQ KQNLLAPQTL 60
PSKSNESHDH MDDMDDEDDD DHVDSQDSID SNDSDDVDDT DDSHQSDESH HSDESDELVT 120
DFPTDLPATE VFTPWPTVD TYDGRGDSW YGLRSKSKKF RRPDIQYPDA TDEDITSHME 180
SEELNGAYKA IPVAQDLNAP SDWDSRGKDS YETSQLDDQS AETHSHKQSR LYKRKANDES 240
NEHSDVIDSQ ELSKVSREFH SHEFHSHEDM LWDPKSKEE DKHLKFRISH ELDSASSEVN Seq ID NO: 509 DNA sequence
Nucleic Acid Accession tt : AB051390.1
Coding sequence: 34..2457
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AGCGGCCGCβ GCACAAAGTT GGGGGCCGCG AAGATGAGβC TβTCCCCGGC GCCCCTGAAG 60
CTGAGCCGGA CTCCGGCACT GCTGGCCCTG GCGCTGCCCC TGβCCβCGGC GCTGGCCTTC 120
TCCGACGAGA CCCTGGACAA AGTGCCCAAβ TCAGAGβGCT ACTβCAβCCG TATCCTGCGC 180 βCCCAGGGCA CGCGGCGCGA GββCTACACC GAGTTCAGCC TCCGCGTGGA GββCGACCCC 240
GACTTCTACA AGCCGGGAAC CAGCTACCβC GTAACACTTT CAGCTβCTCC TCCCTCCTAC 300
TTCAGAGGAT TCACATTAAT TGCCGTCAGA GAGAACAGAG AGGGTGATAA GGAAGAAGAC 360
CATGCTGGGA CCTTCCAGAT CATAGACGAA GAAGAAACTC AGTTTATGAG CAATTGCCCT 420
GTTGCAGTCA CTGAAAGCAC TCCACGGAGG AGGACCCGGA TCCAGβTGTT TTGGATAGCA 480
CCACCAGCGG GAACAGGCTG CGTGATTCTβ AAG6CCAGCA TCGTACAAAA ACGCATTATT 540
TATTTTCAAG ATGAGGGCTC TCTGACCAAG AAACTTTGTG AACAAGATTC CACATTTGAT 600
GGGGTGACTG ACAAACCCAT CTTAGACTβC TGTCCCTGCG GAACTGCCAA GTACAGACTC 660
ACATTTTATG GGAATTGGTC CGAGAA6ACA CACCCAAAGG ATTACCCTCG TCGGGCCAAC 720
CACTGGTCTG CGATCATCGG AGGATCCCAC TCCAAβAATT ATGTACTGTG GGAATATGβA 780
GGATATGCCA GCβAAβGCGT CAAACAAGTT GCAGAATTGG GCTCACCCGT GAAAATGGAG 840
GAAβAAATTC βACAACAβAG TGATGAGGTC CTCACCGTCA TCAAAGCCAA AGCCCAATGG 900
CCAGCCTGGC AβCCTCTCAA CGTGAGAGCA GCACCTTCAG CTGAATTTTC CGTGGACAGA 960
ACGCGCCATT TAATGTCCTT CCTGACCATG ATGGGCCCTA GTCCCGACTG GAACGTAGGC 1020
TTATCTGCAG AAGATCTGTG CACCAAGGAA TGTGGCTβββ TCCAGAAGGT GGTGCAAGAC 1080
CTGATTCCCT GGGACGCTGG CACCGACAGC GGGβTβACCT ATGAGTCACC CAACAAACCC 1140
ACCATTCCCC AGGAGAAAAT CCGGCCCCTG ACCAβCCTβG ACCATCCTCA GAGTCCTTTC 1200
TATGACCCAG AGGGTGGGTC CATCACTCAA GTAGCCAGAG TTGTCATCGA GAGAATCβCA 1260
CGGAAGGGTβ AACAATGCAA TATTGTACCT GACAATGTCG ATGATATTGT AGCTβACCTG 1320
GCTCCACAAG AGAAAGATGA AGATGACACC CCTGAAACCT GCATCTACTC CAACTGGTCC 1380
CCATGGTCCG CCTGCAGCTC CTCCACCTGT GACAAAGGCA AGAGGATGCG ACAGCGCATG 1440
CTβAAAβCAC AβCTGGACCT CAGCGTCCCC TGCCCTGACA CCCAGGACTT CCAGCCCTGC 1500
ATGβGCCCTG βCTGCAGTGA CGAAGACGGC TCCACCTGCA CCATGTCCGA GTGGATCACC 1560
TGGTCGCCCT GCAGCATCTC CTGCGβCATβ GGCATGAGGT CCCGGGAGAG GTATGTGAAG 1620
CAGTTCCCGG AGGACGGCTC CGTGTGCACG CTGCCCACTG AGGAAACGGA GAAβTGCACG 1680
GTCAACGAGG AGTGCTCTCC CAGCAGCTβC CTGATGACCG AGTβGGGCGA GTGGGACGAG 1740
TGCAGCGCCA CCTGCGGCAT GGβCATβAAG AAGCGGCACC GCATGATCAA βATGAACCCC 1800
GCAGATGGCT CCATGTGCAA AGCCGAGACA TCACAGGCAG AGAAGTGCAT GATGCCAGAG 1860
TGCCACACCA TCCCATGCTT GCTGTCCCCA TβGTCCGAGT GGA6TGACTG CAGCGTGACC 1920
TGCGGGAAGG GCATGCGAAC CCGACAGCGG ATGCTCAAGT CTCTGGCAGA ACTTGGAGAC 1980
TβCAATGAGG ATCTGGAGCA GβTβGAGAAβ TβCATGCTCC CTGAATGCCC CATTGACTGT 2040
GAGCTCACCG AGTGGTCCCA GTGGTCGGAA TGTAACAAGT CATGTGβGAA AGGCCACGTG 2100
ATTCGAACCC GGATGATCCA AATGGAGCCT CAGTTTGβAG GTGCACCCTG CCCAGAGACT 2160
GTGCAβCGAA AAAAGTGCCG CATCCGAAAA TGCCTTCGAA ATCCATCCAT CCAAAAGCTA 2220
CGCTββAβGG AGGCCCGAGA GAGCCGGCGG AGTGAGCACC TGAAGGAAGA GTCTGAAGGG 2280
GAGCAGTTCC CAGGTTGTAG GATGCβCCCA TGGACGGCCT GGTCAGAATG CACCAAACTG 2340
TGCGGAGGTG GAATTCAGGA ACGTTACATG ACTGTAAAGA AGAGATTCAA AAGCTCCCAG 2400
TTTACCAGCT GCAAAGACAA GAAββAβATC AGAGCATGCA ATGTTCATCC TT6TTAGCAA 2460
GGGTACGAGT TCCCCAGGGC TGCACTCTAG ATTCCAGAGT CACCAATGGC TGGATTATTT 2520
GCTTGTTTAA GACAATTTAA ATTGTGTACG CTAGTTTTCA TTTTTGCAGT GTGGTTCGCC 2580
CAGTAβTCTT GT6GATGCCA GAGACATCCT TTCTGAATAC TTCTTGATGG βTACAGGCTG 2640
AGTGGGGCGC CCTCACCTCC AGCCAGCCTC TTCCTGCAGA GGAGTAGTGT CAGCCACCTT 2700
GTACTAAGCT GAAACATGTC CCTCTGGAGC TTCCACCTGβ CCAGGGAGGA CGGAGACTTT 2760
GACCTACTCC ACATGGAGAG GCAACCATGT CTGGAAGTGA CTATGCCTGA GTCCCAGGGT 2820
GCGGCAGGTA GGAAACATTC ACAGATGAAG ACAGCAβATT CCCCACATTC TCATCTTTGG 2880
CCTGTTCAAT GAAACCATTG TTTGCCCATC TCTTCTTAGT GGAACTTTAG GTCTCTTTTC 2940
AAGTCTCCTC AGTCATCAAT AGTTCCTCββ GAAAAACAGA GCTGGTAGAC TTGAAβAβGA 3000
GCATTGATβT TGGGTGGCTT TTGTTCTTTC ACTGAGAAAT TCGGAATACA TTTGTCTCAC 3060
CCCTGATATT GGTTCCTGAT GCCCCCCCAA CAAAAATAAA TAAATAAATT ATGGCTGCTT 3120
TATTTAAATA TAAGGTAGCT AGTTTTTACA CCTβAGATAA ATAATAAGCT TAGAGTGTAT 3180
TTTTCCCΪTG CTTTTGGGGG TTCAGAGGAG TATGTACAAT TCTTCTGGGA AGCCAGCCTT 3240
CTGAACTTTT TGGTACTAAA TCCTTATTGG AACCAAGACA AAGGAAGCAA AATTGGTCTC 3300
TTTAGAGACC AATTTGCCTA AATTTTAAAA TCTTCCTACA CACATCTAGA CGTTCAAGTT 3360
TGCAAATCAG TTTTTAGCAA GAAAACATTT TTGCTATACA AACATTTTGC TAAGTCTGCC 3420
CAAAGCCCCC CCAATGCATT CCTTCAACAA AATACAATCT CTGTACTTTA AAGTTATTTT 3480
AGTCATGAAA TTTTATATGC AGAGAGAAAA AGTTACCGAG ACAGAAAACA AATCTAAGGG 3540
AAAGGAATAT TATGGGATTA AGCTGAGCAA GCAATTCTGG TGGAAAGTCA AACCTGTCAG 3600
TβCTCCACAC CAGGGCTGTG GTCCTCCCAG ACATGCATAG GAATGGCCAC AGGTTTACAC 3660
TGCCTTCCCA GCAATTATAA GCACACCAGA TTCAGGGAGA CTGACCACCA AGGGATAGTG 3720
TAAAAGGACA TTTTCTCAGT TGGGTCCATC AGCAGTTTTT CTTCCTGCAT TTATTGTTGA 3780
AAACTATTGT TTCATTTCTT CTTTTATAββ CCTTATTACT GCTTAATCCA AATGTGTACC 3840
ATTGGTGAGA CACATACAAT GCTCTGAATA CACTACGAAT TTGTATTAAA CACATCAGAA 3900
TATTTCCAAA TACAACATAG TATAGTCCTβ AATATβTACT TTTAACACAA GAGAGACTAT 3960
TCAATAAAAA CTCACTGGGT CTTTCATGTC TTTAAGCTAA GTAAGTGTTC AGAAGGTTCT 4020
TTTTTATATT GTCCTCCACC TCCATCATTT TCAATAAAAG ATAGGGCTTT TGCTCCCTTG 4080
TTCTTGGAGG GACCATTATT ACATCTCTGA ACTACCTTTG TATCCAACAT GTTTTAAATC 4140
CTTAAATGAA TTGCTTTCTC CCAAAAAAAG CACAATATAA AGAAACACAA GATTTAATTA 4200
TTTTTCTACT TGGGGGGAAA AAAGTCCTCA TGTAGAAGCA CCCACTTTTG CAATGTTGTT 4260
CTAAGCTATC TATCTAACTC TCAGCCCATG ATAAAGTTCC TTAAGCTGGT GATTCCTAAT 4320
CAAGGACAAG CCACCCTAGT GTCTCATGTT TβTATTTGGT CCCAGTTGGG TACATTTTAA 4380
AATCCTGATT TTGGAGACTT AAAACCAGGT TAATGGCTAA GAATGGGTAA CATGACTCTT 4440
GTTGGATTGT TATTTTTTGT TTGCAATGGG GAATTTATAA GAAGCATCAA βTCTCTTTCT 4500
TACCAAAGTC TTGTTAGGTG GTTTATAGTT CTTTTGGCTA ACAAATCATT TTGGAAATAA 4560 AGATTTTTTA CTACAAAAAT G Seq ID NO: 510 Protein sequence Protein Accession ft: BAB18461.1
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MRLSPAPLKL SRTPALLALA LPLAAALAFS DETLDKVPKS EGYCSRILRA QGTRREGYTE 60 FSLRVEGDPD FYKPGTSYRV TLSAAPPSYF RGFTLIALRE NREGDKEEDH AGTFQIIDEE 120 ETQFMSNCPV AVTESTPRRR TRIQVFWIAP PAGTGCVILK ASIVQKRIIY FQDEGSLTKK 180 LCEQDSTFDG VTDKPILDCC ACGTAKYRLT FYGNWSEKTH PKDYPRRANH WSAIIGGSHS 240 KNYVLWEYGG YASEGVKQVA ELGSPVKMEE EIRQQSDEVL TVIKAKAQWP AWQPLNVRAA 300 PSAEFSVDRT RHLMSFLTMM GPSPDWNVβL SAEDLCTKEC GWVQKWQDL IPWDAGTDSG 360 VTYESPNKPT IPQEKIRPLT SLDHPQSPFY DPEGGSITQV ARWIERIAR KGEQCNIVPD 420 NVDDIVADLA PEEKDEDDTP ETCIYSNWSP WSACSSSTCD KGKRMRQRML KAQLDLSVPC 480 PDTQDFQPCM GPGCSDEDGS TCTMSEWITW SPCSISCGMβ MRSRERYVKQ FPEDGSVCTL 540 PTEETEKCTV NEECSPSSCL MTEWGEWDEC SATCGMGMKK RHRMIKMNPA DGSMCKAETS 600 QAEKCMMPEC HTIPCLLSPW SEWSDCSVTC GKGMRTRQRM LKSLAELGDC NEDLEQVEKC 660 MLPECPIDCE LTEWSQWSEC NKSCGKGHVI RTRMIQMEPQ FGGAPCPETV QRKKCRIRKC 720 LRNPSIQKLR WREARESRRS EQLKEESEGE QFPGCRMRPW TAWSECTKLC GGGIQERYMT 780 VKKRFKSSQF TSCKDKKEIR ACNVHPC
Seq ID NO: 511 DNA sequence
Nucleic Acid Accession ft: NM_003108.1
Coding sequence: 76..1401
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GGGGTGGGAG GGGGAGGGGG ACCTCCGCAC GAGACCCAGC GGCCCGGGTT GGAβCβTCCA 60 GCCCTGCAAC GGATCATGGT GCAGCAGGCG GAGAGCTTGG AAGCGGAGAG CAACCTGCCC 120 CGGGAGGCGC TGGACACGGA GGAβGGCGAA TTCATGGCTT GCAGCCCGGT GβCCCTGGAC 180 GAGAGCβACC CAGACTGGTG CAAGACGGCG TCGGGCCACA TCAAGCGGCC GATGAACGCG 240 TTCATGGTAT GGTCCAAGAT CGAACGCAGG AAGATCATGG AGCAGTCTCC GGACATGCAC 300 AACGCCGAGA TCTCCAAGAG GCTGGGCAAG CGCTGGAAAA TGCTGAAGGA CAGCGAGAAG 360 ATCCCGTTCA TCCGGGAGGC GGAGCGGCTG CGGCTCAAGC ACATGGCCGA CTACCCCGAC 420 TACAAGTACC GGCCCCGGAA AAAGCCCAAA ATGGACCCCT CGGCCAAGCC CAGCGCCAGC 480 CAGAGCCCAG AGAAβAGCGC GGCCGGCGGC GGCGGCGGGA GCGCGGGCGG AGGCβCGGGC 540 GGTGCCAAGA CCTCCAAGGG CTCCAGCAAβ AAATGCGGCA AGCTCAAGGC CCCCGCGGCC 600 GCGGGCGCCA AGβCβGGCGC GGGCAAGGCG GCCCAGTCCG GGGACTACGG GGGCGCGGGC 660 GACGACTACG TGCTGGGCAG CCTGCGCGTβ AGCGGCTCGG GCGGCGGCGG CGCGGGCAAG 720 ACGGTCAAGT GCGTGTTTCT GGATGAGGAC GACGACGACG ACGACGACGA CGACGAGCTG 780 CAGCTGCAGA TCAAACAGGA GCCGGACGAG GAGGACGAGG AACCACCGCA CCAGCAGCTC 840 CTGCAGCCGC CGGGGCAGCA GCCGTCGCAG CTGCTβAβAC GCTACAACGT CGCCAAAGTG 900 CCCGCCAGCC CTACGCTGAG CAGCTCGGCG GAGTCCCCCG AGGGAGCGAG CCTCTACGAC 960 GAGGTGCGGG CCGGCGCGAC CTCGGGCGCC GGGβGCGβCA GCCGCCTCTA CTACAGCTTC 1020 AAGAACATCA CCAAGCAGCA CCCGCCβCCG CTCGCGCAGC CCGCGCTGTC GCCCGCGTCC 1080 TCGCGCTCGG TGTCCACCTC CTCGTCCAGC AGCAGCGGCA GCAGCAGCGG CAGCAGCGGC 1140 GAGGACGCCG ACGACCTGAT GTTCGACCTG AGCTTGAATT TCTCTCAAAG CGCGCACAGC 1200 GCCAGCGAGC AGCAGCTGGG GGGCGGCGCG GCGGCCGGGA ACCTGTCCCT GTCGCTGGTG 1260 GATAAGGATT TGGATTCGTT CAβCGAGGGC AGCCTGGGCT CCCACTTCGA GTTCCCCGAC 1320 TACTGCACGC CGGAGCTGAG CGAβATGATC GCGGGGGACT GGCTGGAGGC GAACTTCTCC 1380 GACCTGGTGT TCACATATTG AAAGGCGCCC GCTGCTCGCT CTTTCTCTCG GAGGGTGCAG 1440 AGCTGGGTTC CTTGGGAGβA AGTTGTAGTG GTGATGATGA TGATGATGAT AATGATGATG 1500 ATGATGGTGG TGTTGATGGT GGCGGTGGTA GGGTGGAGGG GAGAGAAGAA GATGCTGATG 1560 ATATTGATAA GATGTCGTGA CGCAAAGAAA TTGGAAAACA TGATGAAAAT TTTGGTGGAG 1620 TTAAAGTGAA ATGAGTAGTT TTTAAACATT TTTCCTGTCC TTTTTTTGTC CCCCCTCCCT 1680 TCCTTTATCG TGTCTCAAGG TAGTTGCATA CCTAGTCTGβ AGTTGTGATT ATTTTCCCAA 1740 AAAATGTGTT TTTGTAATTA CTATTTCTTT TTCCTGAAAT TCGTGATTGC AACAAAGGCA 1800 GAGGGGGCGG CGCGGCGGAG GGGAGGTAGG ACCCGCTCCG GAAGβCβCTG TTTGAAGCTT 1860 GTCGGTCTTT GAAGTCTGGA AGACGTCTGC AGAGGACCCT TTTGβCAGCA CAACTGTTAC 1920 TCTAGGGAGT TGGTGGAGAT ATTTTTTTTT CTTAAGAGAA CTTAAAGAAC TGGTGATTTT 1980 TTTTTAACAA AAAAAGGG
Seq ID NO: 512 Protein sequence Protein Accesεion ft: NP_003099.1
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MVQQAESLEA ESNLPREALD TEEGEFMACS PVALDESDPD WCKTASGHIK RPMNAFMVWS 60 KIERRKIMEQ SPDMHNAEIS KRLGKRWKML KDSEKIPFIR EAERLRLKHM ADYPDYKYRP 120 RKKPKMDPSA KPSASQSPEK SAAGGGGβSA GGGAGGAKTS KGSSKKCGKL KAPAAAGAKA 180 GAGKAAQSGD YGGAGDDYVL GSLRVSGS6G GGAGKTVKCV FLDEDDDDDD DDDELQLQIK 240 QEPDEEDEEP PHQQLLQPPG QQPSQLLRRY NVAKVPASPT LSSSAESPEG ASLYDEVRAG 300 ATSGAGββSR LYYSFKNITK QHPPPLAQPA LSPASSRSVS TSSSSSSGSS SGSSGEDADD 360 LMFDLSLNFS QSAHSASEQQ LGGGAAAGNL SLSLVDKDLD SFSEGSLGSH FEFPDYCTPE 420 LSEMIAβDWL EANFSDLVFT Y
Seq ID NO: 513 DNA sequence
Nucleic Acid Accession it: CAT Cluster
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GGTCGACCTA AATCTGATAA CTGGCTTATT ATGTAATTTA TTGGTGTTAT TATAGTAGAG 60
ATTGGTAATC TACAGTAAGA TTTTCAGTTA GGATTTGAGA TTATGATAAT AACTAATAGA 120
ATATTTCTAA ATTGGAATTA GAAGATTGTT GTATGACAGA GAGTCAGGAC TTGCCATTTG 180 GCAAACATCA AAGTCATTGT TTGGTGTGTA ATAGTACAAA ATCATCTTGC TTAACAβAβA 240 AAGGATATCT GTTGCTCCCG AATGAAACAA TTTTTCTGAA ATAGAGβGCC CAGAATTG6T 300 CTCTGACAAT TAATAAAβAC ATCAAAGATA GCAAAATGAT TTTTATATCT TAGGβCCAAT 360 ACTACCAATT TAATAATTAA AACAAGTTCT GGTGAGCTCT GAACTTβGCA GAATTGβTGG 420 CAACATAGAC TTTGGATTTT CCAAATTCCC CACATAAAAC AAAGGGGATC AACTAGATAG 480 AAAAACCAGA AACCTTTGGA AATATCTGTT TAAAAAAAAA AAAAAGTCGA CGCGGGCC
Seq ID NO: 514 DNA sequence
Nucleic Acid Accesεion ft: CAT cluster
11 21 31 41 51
GGAGCCACAG TGAAAGTCAA GAATGTCAGT GATTCCACAT TTAATATCTA CATTTTTβCA 60 GGGCAGTTAC TCTTTTGTAG TATAACATTG AGCTGATAGC ACATAGTGTA GACAAGTGAA 120 TACAGGATTC TCTGGGTTGT ATTCCCAGAA GTCTGGAGGT CATTTGGATA TTTGTGGGCC 180 CTTGGCTTCA CTCTCACTTβ TGTGACACAT AAAAATTGTG ATGAAATGTC CTATAGATGT 240 CCTGCAGGTC TTAAAAGAAC CTTTCCAAAC TATGAAACAG CCCAGCAGCA CTGAGTTAGA 300 GGTAAATTCT GAACCCTTGA ACACTAAAAC TATTCTAACT GCACATAGAA TTGGCAAGTA 360 GCATTCTATG TCTATGAACA GTATGTCTTT TCTATATAAC AGAGAAAATC TTTTTAAGCA 420 AACTACTCAG TTTAAAACCT AATTCTTCTC ATAATCTCAG TACTTTTGAA TGAAGACATA 480 TCAATGCAAC AGTACACTCT TATTCAGGCA TTTGAAAGAA AGAATTCGAG ATCTAGTTTG 540 TATCAGATAT TATAAATTAG TATGGTTTAG TCTTTGTCAT GAAATTCTAC TTAATTTTTG 600 GACTATAGGT TTAAGAATGT AAGCAGAAGT TCTGCACCAA TCAβAATAAG CTACATTATG 660 CTTGAGTGAC AACTACTGTA ATGACAAAAT ATCAGTGGCT TAATACAATG GTTTTTCTCT 720 CATACTTGTT CATAAAGAGT CAGCAAGGAC CCTGCTCATT ATGGTCCCTC AGGGACCCAG 780 GGTTGTTGGA AGCTCCACCA TTTTAβATAG CTCCCTTCAA AGTCAGCCAT CTTTGGCAGT 840 CCATGTCCCC CAACAGGCTG GCAAAATTTG GCTCTGGATG GCTTCAAGGA TTGAGCATCG 900 GGCAβTTTAA ATGCTTTCAA CATGGAAAGT GGACACCGGC CACTCCCACT CACATCCCTT 960 βGGCCAGAAC TAGGTCACTG GGCCCGGACC TAACTTCGGA GGGTTGGGGA ATTGTAATTC 1020 CTCCATGTAC CCAAAGTGGA GAGAAGCCAG ATACTGAGAA ACATCAATAA TGGCTAACAG 1080 AAATCCATTC TACCATTCCC TTTGCCTAAA GTβAAAAGAT GAGTACTTTC ATCAATTTGT 1140 AAACTGTACT TTTGAAGTAA ATCCTGGTAG CTTGCATGGG GGCTGGATTT CCAGAAAGCC 1200 ATATGTAATT TGGGAATGAC ATTCACTTAA GCTCATAGAA TATCATTATT TGATGTAAAA 1260 TCCCCTCATT TGCAATACAG GACCAAAATG CACTAACCAC AAAACCCCCC TCCCCACGGG 1320 GCCCGGGGTC CCTATTCCCC TCCATCCCTT TAAATGAGGC ATTCTATGAT TTGGAATββA 1380 AGCCCAGTTG TAGTCGTAAG AATTTTACTT AATTCAAGAA TTATTCTCAC TGAATATGTG 1440 CCAGTTCTGA AAGGAATGCA AAGTCAAATT TTGCATCTTC TTTGCTCAAG GGCCTTTAGA 1500 TCTAACAACA CAGACATGAT ACAAGGCTGA CAATGACATT ATGATTTAAA TATGTTAAAC 1560 AACTTATTAA ATTGTGAATC AACAAAAAAT TATGTTCTTT ATTTTATGGT TTTGCATAGT 1620 CCTGACTCAC TGCCTACATA CCCCTCTTGT TCCTCAGTTC TTATCCCTGA TTTCTTACAβ 1680 GATGCCCTAA GACAGCTGTA GATGTTTTTA TTTAGCAAAA AAAAAAAAAA AAAAGTCGAC 1740 GCGβCCGCGA ATTTAGTAG
Seq ID NO: 515 DNA sequence Nucleic Acid Accession #: NM_012427 Coding sequence : 43..924
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CTTGTββTTC CTCTCTACTT GGGGAAATCA GGTGCAGCGG CCATGGCTAC AGCAAGACCC 60 CCCTGGATGT GGGTGCTCTG TGCTCTGATC ACAGCCTTGC TTCTGGGββT CACAGAGCAT 120 GTTCTCGCCA ACAATGATGT TTCCTGTGAC CACCCCTCTA ACACCGTGCC CTCTGGβAβC 180 AACCAGGACC TGGGAGCTGG GGCCGGGGAA GACGCCCGGT CGGATGACAG CAGCAGCCGC 240 ATCATCAATG GATCCGACTG CGATATGCAC ACCCAGCCGT GGCAGGCCGC GCTGTTGCTA 300 AGGCCCAACC AGCTCTACTG CGGGGCGβTβ TTGGTGCATC CACAGTGGCT GCTCACGGCC 360 GCCCACTGCA GGAAGAAAGT TTTCAGAGTC CGTCTCGGCC ACTACTCCCT GTCACCAGTT 420 TATGAATCTG GGCAGCAGAT GTTCCAGGGG GTCAAATCCA TCCCCCACCC TGGCTACTCC 480 CACCCTGGCC ACTCTAACGA CCTCATGCTC ATCAAACTGA ACAGAAGAAT TCGTCCCACT 540 AAAGATGTCA GACCCATCAA CGTCTCCTCT CATTGTCCCT CTGCTGGGAC AAAGTGCTTG 600 GTGTCTGGCT GGGGGACAAC CAAGAGCCCC CAAGTGCACT TCCCTAAGGT CCTCCAGTGC 660 TTGAATATCA GCGTGCTAAG TCAGAAAAGG TGCGAGGATG CTTACCCGAβ ACAGATAGAT 720 GACACCATGT TCTGCGCCGG TGACAAAGCA GGTAGAGACT CCTGCCAGGG TGATTCTGGG 780 GGGCCTGTGG TCTGCAATGG CTCCCTGCAG GGACTCβTGT CCTGGGGAGA TTACCCTTGT 840 GCCCGGCCCA ACAGACCβGG TGTCTACACG AACCTCTGCA AGTTCACCAA GTGβATCCAG 900 GAAACCATCC AGβCCAACTC CTGAGTCATC CCAGβACTCA GCACACCGGC ATCCCCACCT 960 GCTGCAGGGA CAGCCCTGAC ACTCCTTTCA GACCCTCATT CCTTCCCAGA GATGTTβAGA 1020 ATGTTCATCT CTCCAGCCCC TGACCCCATG TCTCCTGGAC TCAGGGTCTG CTTCCCCCAC 1080 ATTβGGCTGA CCGTGTCTCT CTAGTTGAAC CCTGGGAACA ATTTCCAAAA CTGTCCAGGG 1140 CGGGGGTTGC GTCTCAATCT CCCTGGGGCA CTTTCATCCT CAAGCTCAGG GCCCATCCCT 1200 TCTCTGCAGC TCTGACCCAA ATTTAGTCCC AGAAATAAAC TGAGAAGTGG AAAAAAAAAA
Seq ID NO: 516 Protein sequence Protein Accession tt : NP 036559
11 21 31 41 51
I I I
MATARPPWMW VLCALITALL LGVTEHVLAN NDVSCDHPSN TVPSGSNQDL GAGAGEDARS 60 DDSSSRIING SDCDMHTQPW QAALLLRPNQ LYCGAVLVHP QWLLTAAHCR KKVFRVRLGH 120 YSLSPVYESG QQMFQGVKSI PHPGYSHPβH SNDLMLIKLN RRIRPTKDVR PINVSSHCPS 180 AGTKCLVSGW GTTKSPQVHF PKVLQCLNIS VLSQKRCEDA YPRQIDDTMF CAGDKAGRDS 240 CQGDSGGPW CNGSLQGLVS WGDYPCARPN RPGVYTNLCK FTKWIQETIQ ANS Seq ID NO: 517 DNA sequence Nucleic Acid Accession ft: NM_001719 Coding sequence: 123..1418
11 21 31 41 51
I I I I I
GGGCGCAGCβ GGGCCCGTCT GCAGCAAGTβ ACCGACGGCC GββACCβCCG CCTGCCCCCT 60 CTGCCACCTG GGGCGGTGCG CGCCCGGAGC CCGGAGCGCG GGTAGCGCGT AGAGCCGGCG 120 CGATGCACGT GCGCTCACTG CβAGCTGCGG CGCCGCACAC CTTCGTGGCG CTCTGGGCAC 180 CCCTGTTCCT GCTGCGCTCC βCCCTGGCCG ACTTCAGCCT GGACAACGAG GTGCACTCGA 240 GCTTCATCCA CCGGCGCCTC CGCAGCCAGG AGCGGCGGGA GATGCAGCGC GAGATCCTCT 300 CCATTTTGGG CTTGCCCCAC CGCCCβCGCC CGCACCTCCA GGβCAAGCAC AACTCGGCAC 360 CCATGTTCAT GCTGGACCTG TACAACGCCA TGGCGGTGGA GGAGGGCGGC GGGCCCGGCG 420 GCCAGGGCTT CTCCTACCCC TACAAGGCCG TCTTCAGTAC CCAGGGCCCC CCTCTGGCCA 480 GCCTGCAAGA TAGCCATTTC CTCACCGACG CCGACATGGT CATGAGCTTC GTCAACCTCG 540 TGGAACATGA CAAGGAATTC TTCCACCCAC GCTACCACCA TCGAGAGTTC CGGTTTGATC 600 TTTCCAAGAT CCCAGAAGGG GAAGCTGTCA CGGCAGCCGA ATTCCGGATC TACAAGGACT 660 ACATCCGGGA ACGCTTCGAC AATGAGACGT TCCGGATCAG CGTTTATCAβ GTGCTCCAGG 720 AGCACTTGGG CAGGGAATCG GATCTCTTCC TGCTCGACAβ CCGTACCCTC TGGGCCTCGG 780 AGGAGGGCTG GCTGGTGTTT GACATCACAG CCACCAGCAA CCACTGGGTG GTCAATCCGC 840 eecACAACCT GGGCCTGCAG CTCTCGGTGG AGACGCTGGA TGββCAGAGC ATCAACCCCA 900
AGTTGGCGGG CCTGATTGGG CGGCACGGGC CCCAGAACAA GCAGCCCTTC ATGGTGGCTT 960 TCTTCAAGGC CACGGAGGTC CACTTCCGCA GCATCCGGTC CACGGGGAGC AAACAGCβCA 1020 βCCAGAACCG CTCCAAGAGG CCCAAGAACC AGGAAGCCCT GCGGATGGCC AACGTGGCAG 1080 AGAACAGCAG GAGCGACCAG AGGCAGGCCT GTAAGAA6CA CGAGCTGTAT GTCAGCTTCC 1140 GAGACCTGGG CTGGCAGGAC TGGATCATCG CGCCTGAAGG CTACGCCGCC TACTACTGTG 1200 AGGGGGAGTβ TGCCTTCCCT CTβAACTCCT ACATGAACGC CACCAACCAC GCCATCGTGC 1260 AGACGCTGGT CCACTTCATC AACCCGβAAA CGGTGCCCAA GCCCTGCTGT GCGCCCACGC 1320 AGCTCAATGC CATCTCCGTC CTCTACTTCG ATGACAGCTC CAACGTCATC CTGAAGAAAT 1380 ACAGAAACAT GGTGGTCCGG GCCTGTGGCT GCCACTAGCT CCTCCGAGAA TTCAGACCCT 1440 TTGββGCCAA GTTTTTCTGG ATCCTCCATT GCTCGCCTTG GCCAGGAACC AGCAGACCAA 1500 CTGCCTTTTG TGAGACCTTC CCCTCCCTAT CCCCAACTTT AAAGGTGTGA βAGTATTAGG 1560 AAACATGAGC AGCATATGGC TTTTGATCAG TTTTTCAGTG βCAGCATCCA ATGAACAAGA 1620 TCCTACAAGC TGTGCAGGCA AAACCTAGCA GGAAAAAAAA ACAACGCATA AAGAAAAATG 1680 GCCCGGCCAG GTCATTGGCT GGGAAβTCTC AGCCATGCAC GβACTCGTTT CCAGAGGTAA 1740 TTATGAGCGC CTACCAGCCA GGCCACCCAG CCGTGGGAGG AAGGGGGCGT GGCAAGββGT 1800 GGβCACATTG GTGTCTGTGC GAAAGGAAAA TTGACCCGGA AGTTCCTGTA ATAAATGTCA 1860 CAATAAAACG AATGAATG
Seq ID NO: 518 Protein sequence Protein Accession #: NP 001710
11 21 31 41 51
I I I I I
MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS 60 ILGLPHRPRP HLQGKHNSAP MFMLDLYNAM AVEEGGβPβG QGFSYPYKAV FSTQGPPLAS 120 LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEGEAVT AAEFRIYKDY 180 IRERFDNETF RISVYQVLQE HLGRESDLFL LDSRTLWASE EGWLVFDITA TSNHWWNPR 240 HNLGLQLSVE TLDβQSINPK LAGLIGRHβP QNKQPFMVAF FKATEVHFRS IRSTGSKQRS 300 QNRSKTPKNQ EALRMANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEGYAAYYCE 360 GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSSNVILKKY 420 RNMWRACGC H
Seq ID NO: 519 DNA sequence Nucleic Acid Accession #.- Eos sequence
Coding sequence: 264..782
11 21 31 41 51
I I I I I
CCCTGCTCCA GTCACACCCG GAAGCTGACT GGTCCACGCA CAGCTGAAGC ATGAGGAAAC 60 TCATCGCGGG ACTAATTTTC CTTAAAATTT AGACTTGCAC AGTAAGGACT TCAACTGACC 120 TTCCTCAGAC TGAGAACTGT TTCCAGTATA TACATCAAGT CACTGAGATC TCCAGCACCC 180 TGCCGGTGGC ACTACTGAGA GACGAGGTGC CAGGGTGGTT CCTGAAAGTG CCTGAβCCCC 240 AACTTATCAG CAAGGAGCTC ATCATGCTGA CAGAAGTCAT GGAGGTCTGG CATGGCTTAG 300 TGATCGCGGT GGTGTCCCTC TTCCTGCAGG CCTGCTTCCT CACCGCCATC AACTACCTGC 360 TCAGCAGGCA CATGGCCCAC AAGAGTGAAC AGATACTGAA AGCGGCCAGT CTCCAGGTTC 420 CCAGβCCCAG CCCTGGCCAC CATCATCCAC CTGCTGTCAA AGAGATGAAβ GAGACTCAGA 480 CAGAGAGAGA CATCCCAATG TCTGATTCCC TTTACAGGCA TGACAGCGAC ACACCCTCAG 540 ATAGCTTββA TAGCTCCTGC AGTTCGCCTC CTGCCTGCCA CeCCACAGAG GATGTGGATT 600 ACACACAAGT CGTCTTTTCT GACCCTGGAβ AACTAAAAAA TGACTCCCCG CTGGACTATG 660 AGAACATAAA GGAAATCACA GATTATGTCA ATGTCAATCC AGAAAGACAC AAGCCCAGTT 720 TCTGGTATTT TGTCAACCCT GCTCTGTCTβ AGCCAGCGGA ATAT6ATCAA GTGGCCATGT 780 GAATTCCAAA TATTTTTAAT GGGGTCCAβT TCTCTATGGA TTCTTACATT TAATTTCTAβ 840 GGAAATGCCA TTTTTCCCCC TTAAACAAGβ CATGGGGCTC ACAAGTCTAT GGAGACAG6C 900 CAAAAAGAAT GTGGAGAAGA AAACTβATAA ATACACAGAG GTCCTCAAGA CCCATGGACT 960 CCTGGTCTGT ACCCAAAAAA GCTGTTCGTT CCTCAAAAAC AAAAACAAGG CTTGGCTGGG 1020 AAAACAGGCC AATGCCCCGG CAAGAAAGGT TGAGATCAGA TGTTAGGAAG AACTTTCAGβ 1080 TAAAGTATGA GAACTATGGA GTCCATCAGC AGAGATAGTA GTβAAβTCTC TCCCCAβGGA 1140 AAATTTTAAA AAGGTTGAAT CAGCTGTTGT AGAGTTCTAT TTGGCAATCT CATGGTTAAA 1200 TGACTTCCCT TTGAGCTCTT TAATTATTGG CAATAAACAA CTTCTTTAAA AGTTTTAAAT 1260 AAAATAGCAA CCACCACCA
Seq ID NO: 520 Protein εequence Protein Accesεion ff: Eos sequence 1 11 21 31 41 51
I I I I I I
MLTEVMEVWH GLVIA SLF LQACFLTAIN YLLSRHMAHK SEQILKAASL QVPRPSPβHH 60 HPPAVKEMKE TQTERDIPMS DSLYRHDSDT PSDSLDSSCS SPPACQATED VDYTQWFSD 120 PβELKNDSPL DYENIKEITD YVNVNPERHK PSFWYFVNPA LSEPAEYDQV AM
Seq ID NO: 521 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 107..328
11 21 31 41 51
I I I I
CTGCTCTGTC T 1GAGCCAGCG GAATATGATC AAGTGGCCAT GTGAATTCCA AATATTTTTA 60 ATGGGGTCCA GTTCTCTATG GATTCTTACA TTTAATTTGT AGGGAAATGC CATTTTTCCC 120 CCTTAAACAA GβCATGGGGC TCACAAGTCT ATGGAGACAG GCCAAAAAGA ATGTGGAGAA 180 GAAAACTGAT AAATACACAG AGGTCCTCAA GACCCATGGA CTCCTGGTCT GTACCCAAAA 240 AAGCTGTTCG TTCCTCAAAA ACAAAAACAA GGCTTGGCTG GGAAAACAGG CCAATGCCCC 300 GGCAAGAAAG GTTGAGATCA GATGTTAGGA AGAACTTTCA GGTAAAGTAT GAGAACTATG 360 GAGTCCATCA GCAGAGATAG TAGTGAAGTC TCTCCCCAGG GAAAATTTTA AAAAGGTTGA 420 ATCAGCTGTT GTAGAGTTCT ATTTGGCAAT CTCATGGTTA AATGACTTCC CTTTGAGCTC 480 TTTAATTATT GGCAATAAAC AACTTCTTTA AAAGTTTTAA ATAAAATAGC AACCACCACC 540 A
Seq ID NO: 522 Protein sequence Protein Accession it: Eos sequence
1 11 21 31 41 51
I I I I I I
MPFFPLKQGM GLTSLWRQAK KNVEKKTDKY TEVLKTHGLL VCTQKSCSFL KNKNKAWLGK QANAPARKVE IRC
Seq ID NO: 523 DNA sequence
Nucleic Acid Accession ft : Eos sequence
Coding sequence: 211..1895
11 21 31
GGATCTGAGG GGCGCCCAGT CACTTCCTCC ACGTTCTCGT GCTGGGCGGG AGβAβCGGAT 60
GGGGCTTGGG AGGCAGCCTG CTCTCCAGTC CCTATCCACC CACAGGTTTT TTGGGTCGGA 120
GAGGAATTAT CTGATAAAAT TCCTGGGTTA ATATTTTTAA AAACGGAGAG TTTTTAAAAA 180
TGATTTTTTT CCCTCGAAAA TGACCTTTTT ATGCTTCGAA GCAGTTTGTC AACCAGCATA 240
GTGCTTTTTC TTTTCTCTTC TTTTTCTACG ATAAATGAAA GCATTTCTTC AAGAAAAAGG 300
CACAGGTTCC TTGAACAGCT GGATTCTGAT GGCACCATTA CTATAGAGGA GCAGATTGTC 360
CTTGTGCTGA AAGCGAAAGT ACAATGTGAA CTCAACATCA CAGCTCAACT CCAGGAGGGA 420
GAAGGTAATT GTTTCCCTGA ATGGGATGGA CTCATTTGTT βGCCCAGAGG AACAGTGGGG 480
AAAATATCGG CTGTTCCATG CCCTCCTTAT ATTTATGACT TCAACCATAA AGGAGTTGCT 540
TTCCGACACT GTAACCCCAA TGGAACATGG GATTTTATGC ACAGCTTAAA TAAAACATGG 600
GCCAATTATT CAGACTβCCT TCGCTTTCTG CAβCCAβATA TCAGCATAGG AAAGCAAGAA 660
TTCTTTGAAC GCCTCTATGT AATGTATACC GTTGGCTACT CCATCTCTTT TGGTTCCTTG 720
CCTβTGGCTA TTCTCATCAT TGGTTACTTC AGACGATTGC ATTGCACTAG GAACTATATC 780
CACATGCACT TATTTGTGTC TTTCATGCTG AGAGCTACAA GCATCTTTGT CAAAGACAGA 840
GTAGTCCATG CTCACATAGG AGTAAAGGAG CTGGAGTCCC TAATAATGCA GGATGACCCA 900
CAAAATTCCA TTGAGGCAAC TTCTGTGGAC AAATCACAAT ATATCGGGTβ CAAGATTGCT 960
GTTGTGATGT TTATTTACTT CCTGGCTACA AATTATTATT GGATCCTGGT GβAAGβTCTC 1020
TACCTGCATA ATCTCATCTT TGTGGCTTTC TTTTCGGACA CCAAATACCT GTGβββCTTC 1080
ATCTTGATAG GCTGGGGGTT TCCAGCAGCA TTTGTTGCAG CATGGGCTGT GGCACGAGCA 1140
ACTCTGGCTG ATGCGAGGTG CTGGGAACTT AGTGCTGGAβ ACATCAAGTG GATTTATCAA 1200 βCACCGATCT TAGCAGCTAT TGGGCTGAAT TTTATTCTGT TTCTGAATAC GGTTAβAGTT 1260
CTAGCTACCA AAATCTΘ3GA GACCAATGCA GTTGGGCATG ACACAAGGAA GCAATACAGG 1320
AAACTGGCCA AATCGACACT GGTCCTGGTC CTAGTCTTTG GAGTGCATTA CATCGTGTTC 1380
GTATGCCTGC CTCACTCCTT CACTGGGCTC GGGTGGGAGA TCCGCATGCA CTGTGAGCTC 1440
TTCTTCAACT CCTTTCAGGG TTTCTTTGTG TCTATCATCT ACTGCTACTG CAATβGAGAβ 1500
CTTCAGGCAG AGGTGAAGAA GATGTGGAGT CGGTGGAATC TCTCCGTGGA CTGGAAAAGG 1560
ACACCGCCAT GTGGCAGCCG CAGATGCGGC TCAGTGCTCA CCACCGTGAC GCACAGCACC 1620
AGCAGCCAGT CACAGGTGGC GGCCAGCACA CGCATGGT6C TTATCTCTGβ CAAAGCTGCC 1680
AAGATCGCCA GCAGACAGCC TGACAβCCAC ATCACTTTAC CTGGCTATGT CTGGAGTAAC 1740
TCAGAGCAGG ACTCCCTβCC ACACTCTTTC CACGAGGAGA CCAAGGAAβA TAGTβGGAGG 1800
CAGGGAGATG ATATTCTAAT GGAGAAGCCT TCCAGGCCTA TGGAATCTAA CCCAGACACT 1860
GAAGGATGCC AAGGAGAAAC TGAGGATGTT CTCTGA
Seq ID NO: 524 Protein sequence
Protein Accession # : Eos sequence
1 11 21 31 41 51 1 1 1 1 | 1 1 t i l l 1 MLRSSLSTSI VLFLFSSFST INESISSRKR HRFLEQLDSD GTITIEEQIV LVLKAKVQCE 60
LNITAQLQEG EGNCFPEWDG LICWPRCTVG KISAVPCPPY IYDFNHKGVA FRHCNPNβTW 120
DFMHSLNKTW ANYSDCLRFL QPDISIGKQE FFERLYVMYT VGYSISFGSL AVAILIIβYF 180
RRLHCTRNYI HMHLFVSFML RATSIFVKDR WHAHIGVKE LESLIMQDDP QNSIEATSVD 240
KSQYIGCKIA WMFIYFLAT NYYWILVEGL YLHNLIFVAF FSDTKYLWGF ILIGWGFPAA 300
FVAAWAVARA TLADARCWEL SAGDIKWIYQ APILAAIGLN FILFLNTVRV LATKIWETNA 360
VGHDTRKQYR KLAKSTLVLV LVFGVHYIVF VCLPHSFTGL GWEIRMHCEL FFNSFQGFFV 420
SIIYCYCNGE VQAEVKKMWS RWNLSVDWKR TPPCGSRRCβ SVLTTVTHST SSQSQVAAST 480 RMVLISGKAA KIASRQPDSH ITLPGYVWSN SEQDCLPHSF HEETKEDSGR QGDDILMEKP SRPMESNPDT EGCQ6ETEDV L
Seq ID NO: 525 DNA sequence Nucleic Acid Accession #: NM_005048 Coding sequence: 143..1795
11 21 31
GGCCGβTGGC CCGGGCCCGA CCAGCCCAGC TGCGCGTCGT TACTG6CCAC AAGTTTGCTC 60
TGGGCCAGCC AAGTTGGCAA CTTGGAAGCT TCTCCCGGGC TCTGGAGGAG GGTCCCTGCT 120
TCTTCCTACA GCCGTTCCGG GCATGβCCGG GCTGGGGGCG TCGCTCCACG TCTGGGGTTβ 180
GCTAATGCTC GGCAGCTGCC TCCTGGCCAG AGCCCAGCTG GATTCTGATG GCACCATTAC 240
TATAGAGGAG CAGATTGTCC TTGTGCTGAA AGCGAAAGTA CAATGTGAAC TCAACATCAC 300
AGCTCAACTC CAGGAGGGAG AAGGTAATTG TTTCCCTGAA TGGGATGGAC TCATTTGTTG 360
GCCCAGAGGA ACAGTGGGGA AAATATCGβC TGTTCCATGC CCTCCTTATA TTTATGACTT 420
CAACCATAAA GGAGTTGCTT TCCGACACTG TAACCCCAAT GGAACATGGG ATTTTATGCA 480
CAGCTTAAAT AAAACATGGG CCAATTATTC AGACTGCCTT CGCTTTCTGC AGCCAGATAT 540
CAGCATAGGA AAGCAAGAAT TCTTTGAACG CCTCTATGTA ATGTATACCG TTGGCTACTC 600
CATCTCTTTT GGTTCCTTGG CTGTGGCTAT TCTCATCATT GGTTACTTCA GACGATTβCA 660
TTGCACTAGG AACTATATCC ACATGCACTT ATTTGTGTCT TTCATGCTGA GAGCTACAAG 720
CATCTTTGTC AAAGACAGAG TAGTCCATGC TCACATAGGA GTAAAGGAGC TGGAGTCCCT 780
AATAATGCAβ GATGACCCAC AAAATTCCAT TGAGGCAACT TCTGTGGACA AATCACAATA 840
TATCGGGTGC AAGATTGCTG TTβTGATGTT TATTTACTTC CTGGCTACAA ATTATTATTG 900
GATCCTGGTβ GAAGβTCTCT ACCTGCATAA TCTCATCTTT GTGGCTTTCT TTTCGGACAC 960
CAAATACCTG TGGGGCTTCA TCTTGATAGG CTGGGGGTTT CCAGCACCAT TTGTTGCAGC 1020
ATGGGCTGTG GCACGAGCAA CTCTGGCTGA TGCGAGGTGC TGGβAACTTA GTGCTβGAGA 1080
CATCAAGTGG ATTTATCAAG CACCGATCTT AGCAGCTATT GGGCTGAATT TTATTCTGTT 1140
TCTGAATACG GTTAGAGTTC TAGCTACCAA AATCTGGGAG ACCAATGCAG TTGGGCATGA 1200
CACAAGGAAG CAATACAGβA AACTGGCCAA ATCGACACTG GTCCTGGTCC TAGTCTTTGG 1260
AGTGCATTAC ATCGTGTTCG TATGCCTGCC TCACTCCTTC ACTGGGCTCG GβTGGGAGAT 1320
CCGCATGCAC TGTGAβCTCT TCTTCAACTC CTTTCAGGGT TTCTTTGTGT CTATCATCTA 1380
CTGCTACTGC AATGGAGAGG TTCAGGCAGA GGTGAAGAAG ATGTGGAGTC GGTGGAATCT 1440
CTCCGTGGAC TGGAAAAGGA CACCGCCATG TGGCAGCCGC AGATGCGGCT CAβTβCTCAC 1500
CACCGTGACG CACAGCACCA GCAGCCAβTC ACAGGTGGCG GCCAGCACAC GCATGGTGCT 1560
TATCTCTGGC AAAGCTGCCA AGATCGCCAG CAGACAGCCT GACAGCCACA TCACTTTACC 1620
TGGCTATGTC TGGAβTAACT CAGAGCAGGA CTGCCTGCCA CACTCTTTCC ACGAGGAGAC 1680
CAAGGAAGAT AGTGGGAGGC AGβGAGATGA TATTCTAATG GAGAAGCCTT CCAGGCCTAT 1740
GGAATCTAAC CCAGACACTβ AAGβATβCCA AGGAGAAACT GAGGATGTTC TCTGAATGGA 1800
CATTTGTGGC TGACTTTCAT GGGCTGGTCC AATGGCTGGT TGTGTGAGAG GGCTTGGCTG 1860
ATACTCCTAT GCTTGAβTTC AAAGGCTGAA AATTCAGTTA AGGTGTTACT TAATAATAGT 1920
TTTTAGGCTC CATGAATTGG CTCCTGTAAA TACTAACGAC ATGAAAATGC AAGTβTCAAT 1980
GGAGTAGTTT ATTACCTTCT ATTGGCATCA AGTTTTCCTC TAAATTAATG TATGGTATTT 2040
GCTCTGTGAT TGTTCATTTT TTTCTGCTAC TTTTGGGTAG AAAAAAGATT CAATTGCTTG 2100
GCTGTAGCTT TCTCTCATAT ATATCACCCT AAATATAATG AAGATCTTTT AGTGTGTATC 2160
ATTTTCCTTT TAGAAACTAG TATTCTCTTA TTTCTTACTT TAATGTACTT CTATCACTGC 2220
ATTTATTTTG CCTGTGCATA GGAGCAATTA GGATCTAAAA AAATATATGG GAAGATAAAA 2280
GATCTAAGAA CAAGTACTTG CTGGAAAATT AGTTGGCTGG ACATTGATAA AATAATGCAT 2340
TTATAACAAT TACATGTGTT TTTGGGAACA AGGAAAATTT CTCAAAAAAG AATATTTCAC 2400
ACATCCCTTC TTTTGAATGG CCTCTTTGTG ACCAGCCAGA CCTCAGGTCT TCACTCTTTC 2460
TTCTTTGTAA ACCATGTCAT GTGGAAAGAT TTCCTCAGTT AGTGAGCTTG TGTCTGCAAA 2520
TTGATTTTGT TTGTAATGTA TTTTGATAGC AAATCATGCT GCATCTATAT CTTTTTCTTG 2580
TTTβAGCTCT TACTACATTG TACATGGCAT GTGGGATCAA TTAAAAATTT GTTTTAAAAA 2640 T
Seq ID NO: 526 Protein sequence Protein Accession ft: NP 005039
11 21 31 41 51
I I I I I
MAGLGASLHV WGWLMLGSCL LARAQLDSDG TITIEEQIVL VLKAKVQCEL NITAQLQEGE 60 GNCFPEWDGL ICWPRGTVGK ISAVPCPPYI YDFNHKGVAF RHCNPNGTWD FMHSLNKTWA 120 NYSDCLRFLQ PDISIGKQEF FERLYVMYTV GYSISFGSLA VAILIIGYFR RLHCTRNYIH 180 MHLFVSFMLR ATSIFVKDRV VHAHIGVKEL ESLIMQDDPQ NSIEATSVDK SQYIGCKIAV 240 VMFIYFLATN YYWILVEGLY LHNLIFVAFF SDTKYLWGFI LIGWGFPAAF VAAWAVARAT 300 LADARCWELS AGDIKWIYQA PILAAIGLNF ILFLNTVRVL ATKIWETNAV GHDTRKQYRK 360 LAKSTLVLVL VFGVHYIVFV CLPHSFTGLG WEIRMHCELF FNSFQGFFVS IIYCYCNGEV 420 QAEVKKMWSR WNLSVDWKRT PPCGSRRCGS VLTTVTHSTS SQSQVAASTR MVLISβKAAK 480 IASRQPDSHI TLPGYVWSNS EQDCLPHSFH EETKEDSGRQ GDDILMEKPS RPMESNPDTE 540 GCQGETEDVL
Seq ID NO: 527 DNA sequence Nucleic Acid Accession #: XM_036683 Coding sequence: 38..3655
11 21 31 41 51
I I I I I
GCTTTGCCCA GTAGTTGGAA AGTGAACTCG ACTCβTGATG GTTCTCCTGT CACTTTGGTT 60 GATAGCAGCC GCTCTGGTAG AGGTTAGGAC TTCAGCTGAT GGACAAGCTG GTAATGAAGA 120 AATGGTGCAA ATAGATTTAC CAATAAAGAG ATATAGAGAG TATβAGCTGG TGACTCCAGT 180 CAGCACAAAT CTAGAAGGAC GCTATCTCTC CCATACTCTT TCTGCCAGTC ACAAAAAGAG 240 GTCAGCGAGG GACGTGTCTT CCAACCCTGA GCAGTTGTTC TTTAACATCA CGGCATTTGG 300 AAAAGATTTT CATCTGCβAC TAAAGCCCAA CACTCAACTA GTAGCTCCTβ GGGCTGTTGT 360 GGAGTGGCAT GAGACATCTC TβGTGCCTGG GAATATAACC βATCCCATTA ACAACCATCA 420 ACCAGGAAGT GCTAC6TATA GAATCCGGAA AACAGAGCCT TTGCAβACTA ACTGTGCTTA 480
TβTTGGTGAC ATCGTGGACA TTCCAGGAAC CTCTGTTGCC ATCAGCAACT GTGATβGTCT 540
GGCTGGAATG ATAAAAAGTG ATAATGAAGA GTATTTCATT GAACCCTTGG AAAGAGGTAA 600
ACAGATGGAG GAAGAAAAAG GAAGGATTCA TGTTGTCTAC AAGAGATCAG CTGTAGAACA 660
GGCTCCCATA GACATGTCCA AAGACTTCCA CTACAGAGAG TCGGACCTGG AAGGCCTTGA 720
TGATCTAGGT ACTGTTTATG GCAACATCCA CCAGCAGCTG AATGAAACAA TGAGACGCCG 780
CAGACACGCG GGAGAAAACG ATTACAATAT CGAGGTACTG CTGGβAβTGG ATGACTCTGT 840
GCTCCGTTTC CATGGCAAAG AGCACGTCCA AAACTACCTC CTGACCCTAA TGAACATTGT 900 βAATGAAATT TACCATGATG AGTCCCTCGG AβTGCATATA AATGTβGTCC TGGTGCGCAT 960
GATAATGCTG GGATATGCAA AGTCCATCAG CCTCATAGAA AGGGGAAACC CATCCAGAAG 1020
CTTGGAGAAT GTGTGTCGCT GGGCGTCCCA ACAGCAAAGA TCTGATCTCA ACCACTCTGA 1080
ACACCATGAC CATGCAATTT TTTTAACCAG GCAAGACTTT GGACCTGCTG GAATGCAAGG 1140
ATATGCTCCA GTCACCGβCA TGTGTCATCC AGTGAGAAGT TGTACCCTGA ATCATGAGGA 1200
TGGTTTTTCA TCTGCTTTTG TAGTAGCCCA TGAAACGGGC CATGTGTTβG GAATGGAGCA 1260
TGATGGACAA GGCAACAβGT CTGGTGATGA GACTGCTATG GGAAGTGTCA TGGCTCCCTT 1320
GGTACAAGCA GCATTCCATC GTTACCACTG GTCCCGATGC AGTGGTCAAβ AACTGAAAAG 1380
ATATATCCAT TCCTATGACT GTCTCCTTGA TGACCCTTTT GATCATGATT GGCCTAAACT 1440
CCCAGAACTT CCTGGAATCA ATTATTCTAT GβATGAβCAA TGTCGTTTTG ATTTTGGTGT 1500
TGGCTATAAA ATβTβCACCG CGTTCCGAAC CTTTGACCCA TGTAAACAGC TGTGGTGTAG 1560
CCATCCTGAT AATCCCTACT TTTGTAAGAC TAAAAAGββA CCTCCACTTG ATGββACTGA 1620
ATGTGCTGCT GGAAAATβGT GCTATAAGGG TCATTGCATG TGGAAGAATG CTAATCAGCA 1680
AAAACAAGAT CGCAATTGGG GGTCATGGAC TAAATTTGβC TCCTGTTCTG GGACATGTGG 1740
AACTGGTGTT CGTTTCAGAA CACGCCAGTG CAATAATCCC ATGCCCATCA ATGGTGGTCA 1800
GGATTGTCCT GGTGTTAATT TTGAGTACCA GCTTTGTAAC ACAGAAGAAT GCCAAAAACA 1860
CTTTGAGGAC TTCAGAGCAC AGCAGTGTCA GCAGCGAAAC TCCCACTTTG AATACCAGAA 1920
TACCAAACAC CACTGGTTGC CATATGAACA TCCTGACCCC AAGAAAAGAT GCCACCTTTA 1980
CTGTCAGTCC AAGGAGACTG GAGATGTTGC TTACATGAAA CAACTGGTGC ATGATGGAAC 2040
GCACTGTTCT TACAAAGATC CATATAGCAT ATGTGTGCGA GGAGAGTGTG TGAAAGTGGG 2100
CTGTGATAAA GAAATTGβTT CTAATAAGGT TGAGGATAAG TGTGGTβTCT GTGGAGGAGA 2160
TAATTCCCAC TGCCβAACCG TGAAGGGGAC ATTTACCAGA ACTCCCAGGA AGCTTGGGTA 2220
CCTTAAGATG TTTβATATAC CCCCTGGGGC TAβACATGTG TTAATCCAAG AAGACGAGGC 2280
TTCTCCTCAT ATTCTTGCTA TTAAGAACCA GGCTACAGGC CATTATATTT TAAATGGCAA 2340
AGGGGAGGAA GCCAAGTCGC GGACCTTCAT ACATCTTGGT GTGGAGTGGG ATTATAACAT 2400
TGAAGATGAC ATTGAAAβTC TTCACACCGA TGGACCTTTA CATβATCCTG TTATTGTTTT 2460
GATTATACCT CAAGAAAATG ATACCCGCTC TAGCCTGACA TATAAGTACA TCATCCATGA 2520
AGACTCTGTA CCTACAATCA ACAGCAACAA TGTCATCCAG GAAGAATTAG ATACTTTTGA 2580
GTGGGCTTTG AAGAGCTGGT CTCAGTGTTC CAAACCCTGT GGTGGAβGTT TCCAGTACAC 2640
TAAATATGGA TGCCβTAβGA AAAGTGATAA TAAAATGGTC CATCGCAGCT TCTGTGAGGC 2700
CAACAAAAAG CCGAAACCTA TTAGACGAAT GTGCAATATT CAACAβTGTA CACATCCACT 2760
CTGGGTAGCA GAAGAATβGG AACACTGCAC CAAAACCTGT GGAAGTTCTβ GCTATCAGCT 2820
TCGCACTGTA CGCTGCCTTC AGCCACTCCT TGATGGCACC AACCGCTCTG TGCACAGCAA 2880
ATACTGCATG G6TGACCGTC CCGAGAGCCG CCGGCCCTGT AACAGAβTβC CCTGCCCTGC 2940
ACAGTGGAAA ACAGGACCCT GGAGTGAGTG TTCAGTGACC TGCGGTGAAG GAACGGAGGT 3000
GAGGCAGGTC CTCTGCAGGG CTGGGGACCA CTGTGATGβT GAAAAGCCTG AGTCGGTCAG 3060
AGCCTGTCAA CTGCCTCCTT GTAATGATGA ACCATGTTTG GGAGACAAGT CCATATTCTG 3120
TCAAATGGAA GTGTTGGCAC GATACTGCTC CATACCAGGT TATAACAAGT TATGTTGTGA 3180
GTCCTGCAGC AAGCGCAGTA GCACCCTGCC ACCACCATAC CTTCTAGAAG CTGCTGAAAC 3240
TCATGATGAT GTCATCTCTA ACCCTAGTGA CCTCCCTAGA TCTCTAGTGA TGCCTACATC 3300
TTTGGTTCCT TATCATTCAG AGACCCCTGC AAAGAAGATβ TCTTTGAGTA GCATCTCTTC 3360
AGTGGGAGGT CCAAATGCAT ATβCTGCTTT CAGGCCAAAC AGTAAACCTG ATGGTGCTAA 3420
TTTACGCCAG AGGAβTGCTC AGCAAGCAGG AAGTAAβACT GTGAGACTGG TCACCGTACC 3480
ATCCTCCCCA CCCACCAAGA GGGTCCACCT CAGTTCAGCT TCACAAATGG CTGCTGCTTC 3540
CTTCTTTGCA GCCAGTGATT CAATAGGTGC TTCTTCTCAG GCAAGAACCT CAAAGAAAGA 3600
TGGAAAGATC ATTGACAACA GACGTCCGAC AAGATCATCC ACCTTAGAAA GATGAGAAAG 3660
TGAACCAAAA AGGCTAGAAA CCAGAβGAAA ACCTGGACAA CCTCTCTCTT CCCATGβTGC 3720
ATATGCTTGT TTAAAGTGGA AATCTCTATA GATCGTCAGC TCATTTTATC TGTAATTGGA 3780
AGAACAβAAA GTGCTGGCTC ACTTTCTAGT TGCTTTCATC CTCCTTTTβT TCTGCATTGA 3840
CTCATTTACC AGAATTCATT GGAAGAAATC ACCAAAGATT ATTACAAAAG AAAAATATGT 3900
TGCTAAGATT GTGTTGGTCG CTCTCTGAAG CAGAAAAGGG ACTGGAACCA ATTGTGCATA 3960
TCAGCTGACT TTTTGTTTGT TTTAGAAAAG TTACAβTAAA AATTAAAAAG AGATACCAAT 4020
GGTTTACACT TTAACAAGAA ATTTTGGATA TGGAACAAAG AATTCTTAGA CTTGTATTCC 4080
TATTTATCTA TATTAGAAAT ATTGTATGAβ CAAATTTGCA GCTGTTGTβT AAATACTCTA 4140
TATTβCAAAA ATCAGTATTA TTTTAAGAGA TGTGTTCTCA AATGATTGTT TACTATATTA 4200
CATTTCTGGA TGTTCTAGGT GCCTGTCGTT GAGTATTGCC TTGTTTGACA TTCTATAGGT 4260
TAATTTTCAA AGCAGAGTAT TACAAAAGAG AAGTTAGAAT TACAGCTACT GACAATATAA 4320
AGβGTTTTGT TGAATCAACA ATGTGATACG TAAATTATAG AAAAAGAAAA GAAACACAAA 4380
AGCTATAGAT ATACAGATAT CAGCTTACCT ATTGCCTTCT ATACTTATAA TTTAAAGGAT 4440
TGGTGTCTTA GTACACTTGT GGTCACAGGG ATCAACGAAT AGTAAATAAT GAACTCGTGC 4500
AAGACAAAAC TGAAACCCTC TTTCCAGGAC CTCAGTAGβC ACCGTTGAGG TGTCCTTTβT 4560
TTTTGTGTGT GTGTGTTCTT TTTTAATTTT CGCATTGTTG ACAGATACAA ACAGTTATAC 4620
TCAATGTACT GTAATAATCG CAAAGGAAAA AGTTTTGGGA TAACTTATTT GTATGTTGGT 4680
AGCTGAGAAA AATATCATCA GTCTAGAATT GATATTTGAG TATAGTAGAG CTTTGGGGCT 4740
TTGAAGGCAG GTTCAAGAAA GCATATGTCG ATGGTTGAGA TATTTATTTT CCATATGGTT 4800
CATGTTCAAA TGTTCACAAC CACAATGCAT CTGACTGCAA TAATGTβCTA ATAATTTATG 4860
TCAGTAGTCA CCTTGCTCAC AGCAAAGCCA GAAATGCTCT CTCCAGGβAG TAGATGTAAA 4920
GTACTTGTAC ATAGAATTCA GAACTGAAGA TATTTATTAA AAGTTGATTT TTTTTTCTTC 4980
ATAβTATTTT TATGTACTAA ATATTTACAC TAATATCAAT TACATATTTT GGTAAACTAG 5040
AGAGACATAA TTAGAGATGC ATGCTTTGTT CTGTGCATAG AGACCTTTAA GCAAACTACT 5100
ACAGCCAACT CAAAAGCTAA AACTGAACAA ATTTGATGTT ATGCAAACAT CTTGCATTTT 5160
TAGTAGTTGA TATTAAGTTG ATGACTTGTT TCCCTTCAAG GAAACATTAA ATTGTATGGA 5220
CTCACCTAβC TGTTCAATGA AATTGTβAAT TAGAAACATT TTTAAAAGTT TTTGAAAGAG 5280
ATAAGTGCAT CATGAATTAC ATGTACATβA GAGGAGATAG TGATATCAGC ATAATGATTT 5340
TGAGGTCAGT ACCTGAGCTG TCTAAAAATA TATTATACAA ACTAAAATGT AGATGAATTA 5400
ACCTCTCAAA GCACAGAATG TGCAAGAACT TTTGCATTTT AATCGTTGTA AACTAACAGC 5460 TTAAACTATT GACTCTATAC CTCTAAAGAA TTGCTGCTAC TTTGTGCAAG AACTTTGAAG 5520
GTCAAATTAG GCAAATTCCA GATAGTAAAA CAATCCCTAA GCCTTAAGTC TTTTTTTTTT 5580
CCTAAAAATT CCCATAGAAT AAAATTCTCT CTAGTTTACT TGTGTGTGCA TACATCTCAT 5640
CCACAGGGGA AGATAAAGAT GGTCACACAA ACAβTTTCCA TAAAGATGTA CATATTCATT 5700
ATACTTCTGA CCTTTGGGCT TTCTTTTCTA CTAAGCTAAA AATTCCTTTT TATCAAAGTβ 5760
TACACTACTβ ATGCTGTTTG TTGTACTGAG AGCACGTACC AATAAAAATG TTAACAAAAT 5820 AT
Seq ID NO: 528 Protein sequence Protein Accession if: XP 036683
1 11 21 31 41 51
M IVLLSLWLIA AIALVEVRTSA DIGQAGNEEMV QIIDLPIKRYR EIYELVTPVST NILEGRYLSHT 60 LSASHKKRSA RDVSSNPEQL FFNITAFGKD FHLRLKPNTQ LVAPGAWEW HETSLVPGNI 120
TDPINNHQPG SATYRIRKTE PLQTNCAYVβ DIVDIPGTSV AISNCDGLAG MIKSDNEEYF 180
IEPLERGKQM EEEKGRIHW YKRSAVEQAP IDMSKDFHYR ESDLEGLDDL GTVYGNIHQQ 240
LNETMRRRRH AGENDYNIEV LLGVDDSWR FHGKEHVQNY LLTLMNIVNE IYHDESLGVH 300
INWLVRMIM LGYAKSISLI ERβNPSRSLE NVCRWASQQQ RSDLNHSEHH DHAIFLTRQD 360 FGPAGMQGYA PVTGMCHPVR SCTLNHEDGF SSAFWAHET GHVLGMEHDG QGNRCGDETA 420
MGSVMAPLVQ AAFHRYHWSR CSGQELKRYI HSYDCLLDDP FDHDWPKLPE LPGINYSMDE 480
QCRFDFGVGY KMCTAFRTFD PCKQLWCSHP DNPYFCKTKK GPPLDGTECA AGKWCYKGHC 540
MWKNANQQKQ DGNWGSWTKF GSCSRTCGTG VRFRTRQCNN PMPINGGQDC PGVNFEYQLC 600
NTEECQKHFE DFRAQQCQQR NSHFEYQNTK HHWLPYEHPD PKKRCHLYCQ SKETGDVAYM 660 KQLVHDGTHC SYKDPYSICV RGECVKVGCD KEIGSNKVED KCβVCGGDNS HCRTVKGTFT 720
RTPRKLGYLK MFDIPPGARH VLIQEDEASP HILAIKNQAT GHYILNGKGE EAKSRTFIDL 780
GVEWDYNIED DIESLHTDGP LHDPVIVLII PQENDTRSSL TYKYIIHEDS VPTINSNNVI 840
QEELDTFEWA LKSWSQCSKP CGGGFQYTKY GCRRKSDNKM VHRSFCEANK KPKPIRRMCN 900
IQECTHPLWV AEEWEHCTKT CGSSGYQLRT VRCLQPLLDG TNRSVHSKYC MGDRPESRRP 960 CNRVPCPAQW KTGPWSECSV TCGEβTEVRQ VLCRAGDHCD GEKPESVRAC QLPPCNDEPC 1020
LGDKSIFCQM EVLARYCSIP GYNKLCCESC SKRSSTLPPP YLLEAAETHD DVISNPSDLP 1080
RSLVMPTSLV PYHSETPAKK MSLSSISSVG GPNAYAAFRP NSKPDGANLR QRSAQQAGSK 1140
TVRLVTVPSS PPTKRVHLSS ASQMAAASFF AASDSIGASS QARTSKKDGK IIDNRRPTRS 1200 STLER
Seq ID NO: 529 DNA sequence Nucleic Acid Accesεion #: NM_002774 Coding sequence: 246..980
1 11 21 31 41 51
I I I I I I
AGGCGGACAA AGCCCGATTG TTCCTGGGCC CTTTCCCCAT CGCGCCTGGG CCTGCTCCCC 60
AGCCCGGGGC AGGGGCGGGG GCCAGTβTGG TGACACACGC TGTAGCTGTC TCCCCGGCTG 120
GCTGGCTCGC TCTCTCCTGG GGACACAGAG GTCGGCAGGC AGCACACAGA GGGACCTACG 180
GGCAGCTβTT CCTTCCCCCG ACTCAAGAAT CCCCGGAGGC CCGGAGGCCT GCAGCAGGAG 240
CGGCCATGAA GAAGCTGATG GTGGTGCTGA GTCTGATTβC TβCAGCCTGG GCAGAGGAGC 300
AGAATAAGTT GGTGCATGGC GGACCCTGCG ACAAGACATC TCACCCCTAC CAAGCTGCCC 360
TCTACACCTC GGGCCACTTG CTCTGTGGTG GGβTCCTTAT CCATCCACTG TGGGTCCTCA 420
CAGCTGCCCA CTGCAAAAAA CCGAATCTTC AG6TCTTCCT GGGGAAGCAT AACCTTCGGC 480
AAAGGGAGAG TTCCCAGGAG CAGAGTTCTG TTGTCCGGGC TGTGATCCAC CCTGACTATG 540
ATGCCGCCAG CCATGACCAG GACATCATGC TGTTGCGCCT GGCACGCCCA GCCAAACTCT 600
CTGAACTCAT CCAGCCCCTT CCCCTGGAGA GGGACTGCTC AGCCAACACC ACCAGCTGCC 660
ACATCCTGβG CTGGGGCAAG ACAGCAGATG GTGATTTCCC TGACACCATC CAGTGTGCAT 720
ACATCCACCT GGTGTCCCGT GAGGAGTGTG AGCATGCCTA CCCTGGCCAG ATCACCCAGA 780
ACATGTTGTG TGCTGGGGAT GAGAAGTACG GGAAGGATTC CTGCCAGGGT GATTCTGGGG 840
GTCCGCTGGT ATGTGGAGAC CACCTCCGAG GCCTTGTGTC ATGGGGTAAC ATCCCCTGTG 900
GATCAAAGGA GAAGCCAGGA GTCTACACCA ACGTCTGCAG ATACACβAAC TGGATCCAAA 960
AAACCATTCA GGCCAAGTGA CCCTGACATG TGACATCTAC CTCCCGACCT ACCACCCCAC 1020
TGGCTGGTTC CAGAACGTCT CTCACCTAGA CCTTGCCTCC CCTCCTCTCC TGCCCAGCTC 1080
TGACCCTGAT GCTTAATAAA CGCAGCGACβ TβAGGGTCCT GATTCTCCCT GGTTTTACCC 1140
CAGCTCCATC CTTGCATCAC TβGGGAGGAC GTGATGAGTG AGGACTTGGG TCCTCGGTCT 1200
TACCCCCACC ACTAAGAGAA TACAGGAAAA TCCCTTCTAG GCATCTCCTC TCCCCAACCC 1260
TTCCACACGT TTGATTTCTT CCTGCAGAGG CCCAGCCACG TGTCTββAAT CCCAGCTCCG 1320
CTGCTTACTG TCGGTGTCCC CTTGGGATGT ACCTTTCTTC ACTGCAGATT TCTCACCTGT 1380
AAGATGAAGA TAAGGATGAT ACAGTCTCCA TCAGGCAGTG GCTGTTGGAA AGATTTAAGA 1440
TTTCACACCT ATGACATACA TGGGATAGCA CCTGGGCCGC CATGCACTCA ATAAAGAATG 1500 TATTTT
Seq ID NO: 530 Protein sequence Protein Accession ft: NP_002765
1 11 21 31 41 51
I I I I I I
MKKLMWLSL IAAAWAEEQN KLVHβGPCDK TSHPYQAALY TSGHLLCGβV LIHPLWVLTA 60 AHCKKPNLQV FLGKHNLRQR ESSQEQSSW RAVIHPDYDA ASHDQDIMLL RLARPAKLSE 120
LIQPLPLERD CSANTTSCHI LGWGKTADGD FPDTIQCAYI HLVSREECEH AYPGQITQNM 180
LCAGDEKYGK DSCQGDSGGP LVCGDHLRGL VSWGNIPCGS KEKPGVYTNV CRYTNWIQKT 240 IQAK Seq ID NO: 531 DNA sequence
Nucleic Acid Accession ft: NM.012152 Coding sequence: 43..1104
1 11 21 31 41 51 CTTCTTTAAA TTTCTTTCTA GGATGTTCAC TTCTTCTCCA CAATGAATGA GTGTCACTAT 60 GACAAGCACA TGGACTTTTT TTATAATAGG AGCAACACTG ATACTGTCGA TGACTGGACA 120 GGAACAAAGC TTGTGATTGT TTTGTGTGTT GGGACGTTTT TCTGCCTGTT TATTTTTTTT 180 TCTAATTCTC TGGTCATCGC GGCAGTGATC AAAAACAGAA AATTTCATTT CCCCTTCTAC 240 TACCTGTTGG CTAATTTAGC TGCTGCCGAT TTCTTCGCTG GAATTGCCTA TGTATTCCTG 300 ATGTTTAACA CAGGCCCAGT TTCAAAAACT TTGACTGTCA ACCGCTGGTT TCTCCGTCAG 360 GGβCTTCTGG ACAGTAGCTT GACTGCTTCC CTCACCAACT TGCTGGTTAT CGCCGTGGAG 420 AGGCACATGT CAATCATGAG GATGCGGGTC CATAGCAACC TGACCAAAAA GAGGGTGACA 480 CTGCTCATTT TGCTTβTCTG GGCCATCGCC ATTTTTATGG GGGCGGTCCC CACACTGGβC 540 TGGAATTGCC TCTGCAACAT CTCTGCCTGC TCTTCCCTGG CCCCCATTTA CAGCAGGAGT 600 TACCTTGTTT TCTGGACAGT GTCCAACCTC ATGGCCTTCC TCATCATGGT TGTββTGTAC 660 CTGCGGATCT ACGTβTACGT CAAGAGGAAA ACCAACGTCT TGTCTCCGCA TACAAGTGGG 720 TCCATCAGCC GCCGGAβGAC ACCCATGAAG CTAATGAAGA CGGTGATGAC TGTCTTAGGG 780 GCGTTTGTGG TATGCTGGAC CCCGGGCCTG GTGGTTCTGC TCCTCGACGG CCTGAACTCC 840 AGGCAGTGTG GCGTGCAGCA TGTGAAAAGβ TGGTTCCTGC TGCTGGCGCT GCTCAACTCC 900 GTCGTGAACC CCATCATCTA CTCCTACAAβ GACβAGGACA TGTATβGCAC CATGAAβAAβ 960 ATGATCTGCT GCTTCTCTCA GGAGAACCCA GAβAGGCGTC CCTCTCGCAT CCCCTCCACA 1020 GTCCTCAGCA GGAGTGACAC AGGCAGCCAG TACATAGAGG ATAGTATTAG CCAAββTβCA 1080 GTCTGCAATA AAAGCACTTC CTAAACTCTG GATGCCTCTC GGCCCACCCA GGTGATGACT 1140 GTCTTAGG
Seq ID NO: 532 Protein sequence Protein Accession #: NP__036284
1 11 21 51
MNECHYDKHM DFFYNRSNTD TVDDWTGTKL VIVLCVGTFF CLFIFFSNSL VIAAVIKNRK 60
FHFPFYYLLA NLAAADFFAG IAYVFLMFNT GPVSKTLTVN RWFLRQGLLD SSLTASLTNL 120
LVIAVERHMS IMRMRVHSNL TKKRVTLLIL LVWAIAIFMβ AVPTLGWNCL CNISACSSLA 180
PIYSRSYLVF WTVSNLMAFL IMWYLRIY VYVKRKTNVL SPHTSGSISR RRTPMKLMKT 240
VMTVLGAFW CWTPGLWLL LDGLNCRQCG VQHVKRWFLL LALLNSWNP IIYSYKDEDM 300
YGTMKKMICC FSQENPERRP SRIPSTVLSR SDTGSQYIED SISQGAVCNK STS
Seq ID NO: 533 DNA sequence
Nucleic Acid Accession #: NM_002821 Coding sequence: 150..3362
1 11 21 31 41 51
I I I I I I
AACTCCCβCC TCGGGACGCC TCGGGGTCGG GCTCCGGCTG CGGCTGCTGC TGCGGCGCCC 60 GCGCTCCGGT GCGTCCGCCT CCTGTGCCCG CCGCGGAGCA GTCTGCGGCC CGCCGTGCGC 120 CCTCAGCTCC TTTTCCTGAG CCCGCCGCGA TGGGAGCTGC GCGGGGATCC CCGGCCAGAC 180 CCCGCCβGTT GCCTCTGCTC AGCGTCCTGC TGCTGCCGCT GCTGGGCGGT ACCCAGACAG 240 CCATTGTCTT CATCAAGCAG CCGTCCTCCC AGGATGCACT GCAGGGGCGC CGGGCβCTGC 300 TTCGCTGTGA GGTTGAGGCT CCGβGCCCGG TACATGTCTA CTGGCTGCTC GATGGGGCCC 360 CTGTCCAGGA CACGGAGCGG CGTTTCGCCC AGGGCAGCAG CCTGAGCTTT GCAβCTGTGG 420 ACCGGCTβCA βGACTCTGGC ACCTTCCAGT GTGTGGCTCG GGATGATGTC ACTGGAGAAG 480 AAGCCCGCAG TGCCAACβCC TCCTTCAACA TCAAATGGAT TGAGGCAGGT CCTGTGGTCC 540 TGAAβCATCC AGCCTCGGAA GCTGAGATCC AGCCACAβAC CCAGGTCACA CTTCGTTGCC 600 ACATTGATGG GCACCCTCGG CCCACCTACC AATGGTTCCG AGATGGGACC CCCCTTTCTG 660 ATGGTCAGAG CAACCACACA GTCAGCAGCA AGGAGCGGAA CCTGACGCTC CGGCCAGCTG 720 GTCCTGAGCA TAGTGGGCTG TATTCCTGCT GCGCCCACAG TGCTTTTGGC CAGGCTTGCA 780 GCAGCCAGAA CTTCACCTTG AGCATTGCTG ATGAAAGCTT TGCCAGGGTG GTGCTGGCAC 840 CCCAGGACGT GGTAGTAGCG AGGTATGAGG AGGCCATCTT CCATTGCCAG TTCTCAGCCC 900 AGCCACCCCC GAGCCTGCAG TGGCTCTTTG AGGATGAGAC TCCCATCACT AACCGCAGTC 960 GCCCCCCACA CCTCCGCAGA GCCACAGTGT TTGCCAACGG GTCTCTGCTG CTGACCCAGG 1020 TCCGGCCACG CAATGCAGGG ATCTACCGCT GCATTGGCCA GGGGCAGAGG GGCCCACCCA 1080 TCATCCTGGA AGCCACACTT CACCTAGCAG AGATTβAAGA CATGCCGCTA TTTGAGCCAC 1140 GGβTGTTTAC AGCTGGCAGC GAGGAGCGTG TGACCTGCCT TCCCCCCAAG GGTCTGCCAG 1200 AGCCCAGCGT GTGGTGGGAG CACGCGGGAβ TCCGGCTGCC CACCCATGGC AGGGTCTACC 1260 AGAAGGGCCA CGAGCTGGTG TTGGCCAATA TTGCTGAAAG TGATGCTGGT GTCTACACCT 1320 GCCACGCGGC CAACCTGGCT GGTCAGCβGA GACAGGATGT CAACATCACT GTGGCCACTG 1380 TGCCCTCCTG GCTGAAGAAG CCCCAAGACA GCCAGCTGGA GGAGGGCAAA CCCGβCTACT 1440 TGGATTGCCT GACCCAGGCC ACACCAAAAC CTACAGTTGT CTGGTACAGA AACCAGATGC 1500 TCATCTCAGA GGACTCACGG TTCGAGGTCT TCAAGAATGG GACCTTGCGC ATCAACAGCG 1560 TGGAGGTGTA TGATβGGACA TGGTACCGTT GTATGAGCAG CACCCCAGCC GGCAGCATCG 1620 AGGCGCAAGC CCGTGTCCAA GTGCTGGAAA AGCTCAAGTT CACACCACCA CCCCAGCCAC 1680 AGCAGTGCAT GGAGTTTGAC AAGGAGGCCA CGGTGCCCTG TTCAGCCACA GGCCGAGAGA 1740 AGCCCACTAT TAAGTGGGAA CGGGCAGATG GGAGCAGCCT CCCAGAGTGG GTGACAGACA 1800 ACGCTGGGAC CCTGCATTTT GCCCGGGTGA CTCGAβATGA CGCTGGCAAC TACACTTβCA 1860 TTGCCTCCAA CGGβCCGCAG GGCCAGATTC GTβCCCATGT CCAGCTCACT GTGGCAGTTT 1920 TTATCACCTT CAAAGTGGAA CCAGAGCGTA CβACTβTGTA CCAGGGCCAC ACAGCCCTAC 1980 TGCACTGCGA GGCCCAGGGG GACCCCAAGC CGCTGATTCA GTGGAAAGGC AAGGACCGCA 2040 TCCTGGACCC CACCAAGCTG GGACCCAGGA TGCACATCTT CCAGAATGβC TCCCTGGTGA 2100 TCCATβACβT GGCCCCTGAG GACTCAGGCC βCTACACCTG CATTGCAGGC AACAGCTGCA 2160 ACATCAAGCA CACGβAGGCC CCCCTCTATG TCGTGGACAA GCCTGTβCCG GAGGAGTCGG 2220 AG6GCCCTGG CAGCCCTCCC CCCTACAAGA TGATCCAGAC CATTGβGTTG TCGGTGGGTG 2280 CCGCT6T6GC CTACATCATT GCCGTGCTGG GCCTCATGTT CTACTGCAAG AAGCGCTGCA 2340 AAGCCAAGCG GCTGCAGAAG CAGCCCβAGG GCGAGGAGCC AGAGATGGAA TGCCTCAACG 2400 GAGGGCCTTT GCAGAACGGG CAGCCCTCAG CAGAGATCCA AGAAGAAGTG GCCTTGACCA 2460 GCTTGGGCTC CGGCCCCGCG GCCACCAACA AACGCCACAG CACAAGTGAT AAGATGCACT 2520 TCCCACGGTC TAGCCTGCAG CCCATCACCA CGCTGGGGAA GAβTβAGTTT GββGAGGTGT 2580 TCCTGGCAAA GGCTCAGGGC TTGGAGGAGG GAGTGGCAGA GACCCTGGTA CTTGTGAAGA 2640 GCCTGCAβAC GAAGGATGAG CAGCAGCAGC TGGACTTCCG GAGββAβTTG GAGATGTTTG 2700 GGAAGCTGAA CCACGCCAAC GTGGTGCGGC TCCTGGββCT GTGCCGGGAG GCTGAGCCCC 2760 ACTACATGGT GCTGGAATAT GTββATCTGG βAβACCTCAA GCAGTTCCTG AGGATTTCCA 2820 AGAGCAAβGA TGAAAAATTG AAGTCACAGC CCCTCAGCAC CAAGCAGAAG GTGGCCCTAT 2880 GCACCCAGGT AGCCCTββGC ATGGAGCACC TGTCCAACAA CCGCTTTGTG CATAAGGACT 2940 TGGCTβCGCG TAACTGCCTG GTCAGTGCCC AGAGACAAGT GAAGGTGTCT GCCCTGGGCC 3000 TCAGCAAGGA TGTGTACAAC AGTGAβTACT ACCACTTCCG CCAGGCCTGG GTGCCGCTGC 3060 GCTGGATGTC CCCCGAGGCC ATCCTGGAGG GTGACTTCTC TACCAAGTCT GATGTCTGGG 3120 CCTTCGGTGT GCTGATGTGG GAAGTGTTTA CACATGGAGA GATGCCCCAT GGTGGGCAGG 3180 CAGATGATGA AGTACTGGCA GATTTGCAGG CTGGGAAGGC TAGACTTCCT CAGCCCGAGG 3240 GCTGCCCTTC CAAACTCTAT CGβCTβATβC AGCGCTGCTG GGCCCTCAGC CCCAAGGACC 3300 GGCCCTCCTT CAGTGAGATT βCCAGCGCCC TGGGAGACAG CACCGTβGAC AGCAAGCCGT 3360 GAGGAβββAG CCCGCTCAGG ATGβCCTCGG CAGGGGAGGA CATCTCTAGA GβGAAGCTCA 3420 CAGCATGATG GGCAAGATCC CTGTCCTCCT GGGCCCTGAβ GTGCCCTAGT GCAACAGGCA 3480 TTGCTβAββT CTGAGCAGGG CCTGGCCTTT CCTCCTCTTC CTCACCCTCA TCCTTTGβGA 3540 GGCTGACTTG GACCCAAACT GGGCβACTAG GGCTTTGAGC TGββCAβTTT CCCCTβCCAC 3600 CTCTTCCTCT ATCAGGGACA GTβTβββTGC CACAGCTAAC CCCAATTTCT GGCCTTCAAC 3660 TTCTCCCCTT GACCGGGTCC AACTCTβCCA CTCATCTGCC AACTTTGCCT GGGGAGGGCT 3720 AGβCTTGGGA TGAGCTGGGT TTβTGGGGAG TTCCTTAATA TTCTCAAGTT CTGGGCACAC 3780 AGGGTTAATG AGTCTCTTGC CCACTGGTCC ACTTGGGGGT CTACACCAGG ATTATAGAGG 3840 ACACAGCAAG TGAGTCCTCC CCACTCTGGG CTTGTGCACA CTGACCCAGA CCCACβTCTT 3900 CCCCACCCTT CTCTCCTTTC CTCATCCTAA βTGCCTGβCA GATGAAGGAG TTTTCAGGAG 3960 CTTTTGACAC TATATAAACC GCCCTTTTTG TATGCACCAC GββCGGCTTT TATATGTAAT 4020 TGCAGCβTGG GGTGGGTGGG CATGGGAGGT AGGGGTGGGC CCTGβAGATG AGGAGGCTGG 4080 GCCATCCTTA CCCCACACTT TTATTGTTGT CGTTTTTTGT TTGTTTTGTT TTTTTGTTTT 4140 TGTTTTTGTT TTTACACTCG CTGCTCTCAA TAAATAAGCC TTTTTTA
Seq ID NO: 534 Protein εequence Protein Acceεsion ft: NP 002812
1 11 21 31 41 51 1 1 | 1 |1 1 1 11 11
MGAARβSPAR PRRLPLLSVL LLPLLGGTQT AIVFIKQPSS QDALQGRRAL LRCEVEAPGP 60
VHVYWLLDGA PVQDTERRFA QGSSLSFAAV DRLQDSβTFQ CVARDDVTβE EARSANASFN 120
IKWIEAGPW LKHPASEAEI QPQTQVTLRC HIDGHPRPTY QWFRDGTPLS DGQSNHTVSS 180
KERNLTLRPA GPEHSGLYSC CAHSAFGQAC SSQNFTLSIA DESFARWLA PQDWVARYE 240
EAMFHCQFSA QPPPSLQWLF EDETPITNRS RPPHLRRATV FANGSLLLTQ VRPRNAGIYR 300
CIGQGQRGPP IILEATLHLA EIEDMPLFEP RVFTAGSEER VTCLPPKβLP EPSVWWEHAG 360
VRLPTHGRVY QKGHELVLAN IAESDAGVYT CHAANLAGQR RQDVNITVAT VPSWLKKPQD 420
SQLEEGKPGY LDCLTQATPK PTWWYRNQM LISEDSRFEV FKNGTLRINS VEVYDGTWYR 480
CMSSTPAGSI EAQARVQVLE KLKFTPPPQP QQCMEFDKEA TVPCSATGRE KPTIKWERAD 540
GSSLPEWVTD NAGTLHFARV TRDDAGNYTC IASNGPQGQI RAHVQLTVAV FITFKVEPER 600
TTVYQGHTAL LQCEAQGDPK PLIQWKGKDR ILDPTKLGPR MHIFQNGSLV IHDVAPEDSG 660
RYTCIAGNSC NIKHTEAPLY WDKPVPEES EGPGSPPPYK MIQTIβLSVG AAVAYIIAVL 720
GLMFYCKKRC KAKRLQKQPE GEEPEMECLN GGPLQNGQPS AEIQEEVALT SLGSGPAATN 780
KRHSTSDKMH FPRSSLQPIT TLGKSEFGEV FLAKAQGLEE GVAETLVLVK SLQTKDEQQQ 840
LDFRRELEMF GKLNHANVVR LLGLCREAEP HYMVLEYVDL GDLKQFLRIS KSKDEKLKSQ 900
PLSTKQKVAL CTQVALGMEH LSNNRFVHKD LAARNCLVSA QRQVKVSALG LSKDVYNSEY 960
YHFRQAWVPL RWMSPEAILE GDFSTKSDVW AFGVLMWEVF THβEMPHGGQ ADDEVLADLQ 1020
AGKARLPQPE GCPSKLYRLM QRCWALSPKD RPSFSEIASA LGDSTVDSKP
Seq ID NO: 535 DNA sequence
Nucleic Acid Accession if: NM_013952 Coding sequence: 161..1357
60
120
Figure imgf001161_0001
180
ATCTGGCCAT GGAGGGCTGA ACCAGCTGGG AβββGCCTTT GTGAATGGCA GACCTCTGCC 240
GGAAGTGGTC CGCCAGCGCA TCGTAGACCT GGCCCACCAG GGTGTAAGGC CCTGCGACAT 300
CTCTCGCCAG CTCCGCGTCA GCCATGGCTG CGTCAGCAAG ATCCTTGGCA GGTACTACGA 360
GACTGGCAGC ATCCGGCCTG GAGTβATAGG GGGCTCCAAG CCCAAGGTGG CCACCCCCAA 420
GGTGGTGGAG AAGATTGGGG ACTACAAACG CCAGAACCCT ACCATGTTTG CCTGGGAGAT 480
CCGAGACCGG CTCCTGGCTG AGGG∞TCTG TGACAATGAC ACTGTGCCCA GTGTCAGCTC 540
CATTAATAGA ATCATCCGGA CCAAAGTGCA GCAACCATTC AACCTCCCTA TGGACAGCTG 600
CGTGGCCACC AAGTCCCTGA GTCCCGβACA CACGCTGATC CCCAGCTCAG CTGTAACTCC 660
CCCGGAGTCA CCCCAGTCGG ATTCCCTGGG CTCCACCTAC TCCATCAATG GGCTCCTGGG 720
CATCGCTCAG CCTGGCAGCG ACAAGAGGAA AATGGATβAC AGTGATCAGβ ATAβCTGCCG 780
ACTAAGCATT GACTCACAGA GCAGCAGCAG CGβACCCCβA AAGCACCTTC GCACGGATGC 840
CTTCAGCCAβ CACCACCTCG AGCCGCTCGA βTGCCCATTT GAGCGGCAGC ACTACCCAGA 900
GCCCTATGCC TCCCCCAGCC ACACCAAAGG CGAGCAGGGC CTCTACCCGC TGCCCTTGCT 960
CAACAGCACC CTGGACGACG GGAAGGCCAC CCTGACCCCT TCCAACACGC CACTGGGGCG 1020
CAACCTCTCG ACTCACCAGA CCTACCCCGT GGTGGCAGCT CCGCCCTTTT GGATCTGCAG 1080
CAAGTCGβCT CCGGGGTCCC GCCCTTCAAT GCCTTTCCCC ATGCTGCCTC CGTGTACGGG 1140
CAGTTCACGG βCCAGGCCCT CCTCTCAGGG CGAGAGATGG TGGGGCCCAC GCTGCCCGβA 1200
TACCCACCCC ACATCCCCAC CAGCGGACAG GGCAGCTATG CCTCCTCTGC CATCβCAGGC 1260
ATGGTGGCAβ GAAGTGAATA CTCTGGCAAT GCCTATGGCC ACACCCCCTA CTCCTCCTAC 1320
AGCGAGGCCT GGGGCTTCCC CAACTCCAGC TTGCTGAGTT CCCCATATTA TTACAGTTCC 1380
ACATCAAGGC CGAGTGCACC GCCCACCACT GCCACGGCCT TTGACCATCT GTAGTTGCCA 1440
TGGGβACAGT G Seq ID NO: 536 Protein sequence Protein Accession ft: NP_039246
1 11 21 31 41 51 I I I I I I
MPHNSIRSGH GGLNQLGGAF VNGRPLPEW RQRIVDLAHQ GVRPCDISRQ LRVSHGCVSK 60
ILGRYYETGS IRPGVIGGSK PKVATPK E KlβDYKRQNP TMFAWEIRDR LLAEGVCDND 120
TVPSVSSINR IIRTKVQQPF NLPMDSCVAT KSLSPGHTLI PSSAVTPPES PQSDSLβSTY 180
SINβLLGIAQ PGSDKRKMDD SDQDSCRLSI DSQSSSSGPR KHLRTDAFSQ HHLEPLECPF 240 ERQHYPEAYA SPSHTKGEQG LYPLPLLNST LDDGKATLTP SNTPLGRNLS THQTYPWAA 300
PPFWICSKSA PGSRPSMPFP MLPPCTGSSR ARPSSQGERW WGPRCPDTHP TSPPADRAAM 360 PPLPSQAWWQ EVNTLAMPMA TPPTPPTARP GASPTPAC
Seq ID NO: 537 DNA sequence
Nucleic Acid Accession #: NM_003466.1
Coding sequence: 11..1363
1 11 21 31 41 51
I I I I I I
GAATTCGGCG ATGCCTCACA AGTCCATCAG ATCTGGCCAT GGAGGGCTGA ACCAβCTGGG 60
AGGGGCCTTT GTGAATGGCA GACCTCTβCC GGAAGTGGTC CGCCAGGGCA TCGTAGACCT 120
GGCCCACCAG GGTGTAAGGC CCTGCGACAT CTCTCGCCAG CTCCGCGTCA GCCATGGTTG 180
CGTCAGCAAG ATCCTTGGCA GGTACTACGA GACTGGCAGC ATCCGGCCTG GAGTGATAGG 240 βGGCTCCAAG CCCAAGGTGG CCACCCCCAA GGTGGTGGAG AAGATTGGGG ACTACAAACG 300
CCAGAACCCT ACCATCTTTG CCTGGGAGAT CCGAGACCGβ CTCCTGGCTG AGGGCGTCTG 360
TGACAATGAC ACTGTGCCCA GTGTCAGCTC CATTAATAGA ATCATCCGGA CCAAAGTGCA 420
GCAACCATTC AACCTCCCTA TGGACAGCTG CβTGGCCACC AAGTCCCTGA GTCCCGGACA 480
CACGCTGATC CCCAGCTCAG CTGTAACTCC CCCGGAGTCA CCCCAGTCGG ATTCCCTGGG 540
CTCCACCTAC TCCATCAATG GGCTCCTGGG CATCGCTCAG CCTGGCAGCG ACAAGAGGAA 600
AATGGATGAC AGTGATCAGG ATAGCTGCCG ACTAAGCATT GACTCACAGA GCAGCAGCAG 660
CGβACCCCGA AAGCACCTTC GCACGGATGC CTTCAGCCAβ CACCACCTCG AGCCGCTCGA 720
GTGCCCATTT GAGCGGCAGC ACTACCCAGA GGCCTATGCC TCCCCCAGCC ACACCAAAGG 780
CGAGCAGGGC CTCTACCCGC TGCCCTTGCT CAACAGCACC CTGGACGACG βGAAGGCCAC 840
CCTGACCCCT TCCAACACGC CACTGGGGCG CAACCTCTCG ACTCACCAGA CCTACCCCGT 900
GGTGGCAGAT CCTCACTCAC CCTTCGCCAT AAAGCAGGAA ACCCCCGAGG TGTCCAGTTC 960
TAGCTCCACC CCTTCCTCTT TATCTAGCTC CGCCTTTTTG GATCTGCAGC AAGTCGGCTC 1020
CGGGGTCCCG CCCTTCAATG CCTTTCCCCA TGCTGCCTCC GTβTACGGGC AGTTCACGGG 1080
CCAGGCCCTC CTCTCAGGGC GAGAGATGGT GGGGCCCACG CTGCCCGGAT ACCCACCCCA 1140
CATCCCCACC AGCGGACAGG GCAGCTATGC CTCCTCTGCC ATCβCAGGCA TGGTGGCAGG 1200
AAGTGAATAC TCTGGCAATG CCTATGGCCA CACCCCCTAC TCCTCCTACA GCGAGGCCTG 1260
GC6CTTCCCC AACTCCAGCT TGCTGAGTTC CCCATATTAT TACAGTTCCA CATCAAGGGC 1320 GAβTGCACCG CCCACCACTG CCACGGCCTT TGACCATCTG TAGTTGAAGC TT
Seq ID NO: 538 Protein sequence Protein Accession ft: NP_003457
1 11 21 31 41 51
I I I I I I
MPHNSIRSGH GGLNQLGβAF VNGRPLPEW RQRIVDLAHQ GVRPCDISRQ LRVSHGCVSK 60 ILGRYYETGS IRPGVIGGSK PKVATPKWE KIGDYKRQNP TMFAWEIRDR LLAEGVCDND 120
TVPSVSSINR IIRTKVQQPF NLPMDSCVAT KSLSPGHTLI PSSAVTPPES PQSDSLGSTY 180
SINGLLGIAQ PGSDKRKMDD SDQDSCRLSI DSQSSSSGPR KHLRTDAFSQ HHLEPLECPF 240
ERQHYPEAYA SPSHTKGEQG LYPLPLLNST LDDGKATLTP SNTPLGRNLS THQTYPWAD 300
PHSPFAIKQE TPEVSSSSST PSSLSSSAFL DLQQVGSβVP PFNAFPHAAS VYGQFTGQAL 360 LSGREMVGPT LPGYPPHIPT SGQGSYASSA IAGMVAGSEY SGNAYGHTPY SSYSEAWRFP 420 NSSLLSSPYY YSSTSRPSAP PTTATAFDHL
Seq ID NO: 539 DNA sequence Nucleic Acid Accession ft: NM_006799 Coding sequence: 19..963
1 11 21 31 41 51
I I I I I I
GCCGCGGGAG AGGAGGCCAT GGGCGCGCβC GβGGCGCTGC TGCTGGCGCT GCTGCTGGCT 60
CGGGCTGGAC TCAGGAAGCC GGAGTCGCAG GAGGCGGCGC CGTTATCAGG ACCATGCGGC 120
CGACGGGTCA TCACGTCβCβ CATCGTGGGT βGAGAGGACG CCGAACTCGG GCGTTGGCCG 180
TββCACGGGA GCCTGCGCCT βTGβGATTCC CACGTATGCG GAGTGAGCCT GCTCAGCCAC 240
CGCTGGGCAC TCACGGCββC βCACTβCTTT GAAACCTATA GTGACCTTAG TGATCCCTCC 300
GGGTGGATGG TCCAGTTTGG CCAGCTGACT TCCATGCCAT CCTTCTGGAG CCTGCAGGCC 360
TACTACACCC GTTACTTCGT ATCGAATATC TATCTGAGCC CTCGCTACCT GβββAATTCA 420
CCCTATCACA TTGCCTTGGT GAAGCTGTCT GCACCTGTCA CCTACACTAA ACACATCCAG 480
CCCATCTGTC TCCAGGCCTC CACATTTGAG TTTGAGAACC GGACAGACTG CTGββTGACT 540
GGCTGGGGGT ACATCAAAGA GGATGAGGCA CTGCCATCTC CCCACACCCT CCAGGAAGTT 600
CAGGTCGCCA TCATAAACAA CTCTATGTGC AACCACCTCT TCCTCAAGTA CAGTTTCCGC 660
AAGGACATCT TTGGAGACAT GGTTTGTGCT GGCAATGCCC AAGGCGGGAA βGATGCCTGC 720
TTCGGTGACT CAGGTGGACC CTTGGCCTGT AACAAGAATG GACTGTGGTA TCAGATTGGA 780
GTCGTGAGCT GGGGAGTGGG CTGTGGTCGG CCCAATCGGC CCGGTGTCTA CACCAATATC 840
AGCCACCACT TTβAGTGGAT CCAGAAGCTG ATGGCCCAGA GTGGCATGTC CCAGCCAGAC 900
CCCTCCTGGC CGCTACTCTT TTTCCCTCTT CTCTGGGCTG TCCCACTCCT GGGGCCGGTC 960
TGAGCCTAGC TGAGCCCATG CAGCCTGGGG CCACTGCCAA GTCAGGCCCT GGTTCTCTTC 1020 TGTCTTGTTT GGTAATAAAC ACATTCCAGT TGATGCCTTG CAGGGCATTC TTCAAAA
Seq ID NO: 540 Protein sequence Protein Accession ft: NP 006790 11 21 31 41 51
I I I I
MGARGALLLA LLLARAGLRK PESQEAAPLS GPCGRRVITS RIVGGEDAEL GRWPWQGSLR 60 LWDSHVCGVS LLSHRWALTA AHCFETYSDL SDPSGWMVQF GQLTSMPSFW SLQAYYTRYF 120 VSNIYLSPRY LGNSPYDIAL VKLSAPVTYT KHIQPICLQA STFEFENRTD CWVTGWGYIK 180 EDEALPSPHT LQEVQVAIIN NSMCNHLFLK YSFRKDIFGD MVCAGNAQGG KDACFGDSGG 240 PLACNKNGLW YQIGWSWGV GCGRPNRPGV YTNISHHFEW IQKLMAQSGM SQPDPSWPLL 300 FFPLLWALPL LGPV
Seq ID NO: 541 DNA sequence Nucleic Acid Accession ff: NM.014344 Coding sequence: 131..1444
11 21 31 41 51
GCGGCCGCGA TGGGGCCGAA GCGCCCGAAG CCCCGGAGCC CACAAACTGC CGGGCCCGCC 60
TCGCCGCCGG GACCCGGGTG CCTGGGCTCG GCTTGAAGCG GCGGCGβCGC ACCGGCACAG 120
CCGCGGGAGC ATGGGCAGGA GGATGCGGGG CGCCGCCGCC ACCGCGGGGC TCTGGCTGCT 180
GGCGCTGGGC TCGCTGCTGG CGCTβTGGGG AGGGCTCCTG CCGCCGCGGA CCGAGCTCCC 240
CGCCTCCCGβ CCGCCCGAAG ACCGACTCCC ACGGCGCCCG GCCCGGAGCβ GCGGCCCCGC 300
GCCCGCGCCT CGCTTCCCTC TGCCCCCGCC CCTGGCGTGG GACGCCCGCG GCβGCTCCCT 360
GAAAACTTTC CGGGCGCTGC TCACCCTGGC GGCCGGCGCG GACG6CCCGC CCCGGCAGTC 420
CCGGAGCGAG CCCAGGTGGC ACGTGTCAGC CAGGCAGCCC CGGCCGGAGG AGAGCGCCGC 480
GGTGCACGGG GGCGTCTTCT GGAGCCGCGG CCTβGAGGAG CAGGTGCCCC CGGGCTTTTC 540
GGAGGCCCAG GCGGCGGCGT GGCTGGAGGC GGCTCGCGGC GCCCGGATGG TGGCCCTGGA 600
GCGCGGGGGT TGCGGGCGCA GCTCCAACCβ ACTGGCCCGT TTTGCCGACG GCACCCGCGC 660
CTGCGTGCGC TACGGCATCA ACCCβGAGCA GATTCAGGGC GAGGCCCTGT CTTACTATCT 720
GGCGCGCCTG CTGGGCCTCC AGCGCCACGT GCCGCCGCTG GCACTGGCTC GGGTGGAGGC 780
TCGGGGCGCG CAGTGGGCGC AGGTGCAGGA GGAGCTGCGC GCTβCβCACT GGACCGAGGG 840
CAGCGTGGTG AGCCTGACAC GCTGGCTGCC CAACCTCACG GACGTGGTGG TGCCCGCGCC 900
CTGGCGCTCG GAGGACGGCC GTCTGCGCCC CCTCCGGGAT GCCGGGGGTG AGCTGGCCAA 960
CCTCAGCCAG GCGGAGCTβG TGGACCTAGT ACAATGGACC GACTTAATCC TTTTCGACTA 1020
CCTGACGGCC AACTTCGACC GβCTCGTAAG CAACCTCTTC AGCCTGCAGT GGGACCCGCG 1080
CGTCATGCAG CGTGCCACCA GCAACCTGCA CCGCGGTCCG GGCGGβGCGC TGGTCTTTCT 1140
GGACAATGAG GCGGGCTTGβ TGCACGGCTA CCGGGTAGCA GGCATGTGGG ACAAGTATAA 1200
CGAGCCGCTG TTGCAGTCAG TGTGCGTGTT CCGCGAGCGG ACCβCGCGGC GCGTCCTGGA 1260
GCTGCACCGC GGACAGGACG CCGCGGCCCG GCTGCTGCGC CTCTACCββC GCCACGAGCC 1320
TCGCTTCCCC GAGCTGβCCG CCCTTGCAGA CCCCCACGCT CAGCTGCTAC AGCGCCGCCT 1380
CGACTTCCTC GCCAAGCACA TTTTGCACTG TAAGGCCAAG TACGGCCGCC GGTCTGGGAC 1440
TTAGTGTCAC CGGGAGGAAA AGAGAGAGAT CTGGGGCTGG GGTATGβATβ ATGGGGGGAA 1500
GGGCGGTCGC CTCTGCCACT GTCAGGGACC AGCCGGCCAA CGCCCACCCβ CAAAGGTGTC 1560
TAAAAACTTC AGCTTTTCAC CCACCTGCCC CTTTCTTTCA ATCCCACGCT GTTTCCTTTC 1620
AAAGTTCTGG GAGGACGAAC TCACCGAGGC GAGAAGTGTA ACATTCTCTC CACCCAGCTT 1680
ATAAAAGGAT TCTTTACTGT GCCAGCACGG GGATTGGATC CGAAGAAACT GGCTACTGGG 1740
GTTTGGCCCC CGAβTGGCCG TCCCTGTGGG AGATβCACCC CATTCTTGGG CCCCCCTCAT 1800
TCCCTTTCCG AAAAAGGAAA ACTTGCGTTT GAβCCGTTGA GCTAATTCTG CAATTTTCTA 1860
CCAAACAGAG CGCTGGTGGC CCCGGAGCAG GβCTGTβACA TTGGCTGGTG GAGCCCCTTC 1920
CTGTGTTCTC CCTTTβTTCC AGCβCCGCGA TGGTGAGATC ACTGTTCCAA βCAGGGGGAC 1980
GGCTCGCGAT AGGACAAAGA βAβCAGGACC TCCAGACTCT GGGGAGCCCT GCAGACCTTG 2040
ACAATTTGCC TGACTCATTC CTGACCTCTT GTCATTTTGG CCTGAAGGCT ACAAATTCAG 2100
GGTCAGCTGT ATGCACTAAG TCAAATAATG AATTTCTTCC TCCCTCTCGC AACCGACCAA 2160
AATTTTGACA ACGATGATGT TCACCAGAAG GAAAAAAAAA TCAGTTTTAT GCACTTTATT 2220
TTGTTTTGAT TTTCATTTTT TATTAAGAAA AAATTTTATT TTACAGAATT TACCTTCTCT 2280
GTATATATGT GCATAAAGTG TGGTGTAAAT ATACTAAACA AACTTATATT TCAATAAAAG 2340
GGAGTTTAAA ATTTAAAAAA AAAAAAA
Seq ID NO: 542 Protein sequence Protein Accession ff: NP 055159
11 21 31 41 51
I I I I I
MGRRMRβAAA TAGLWLLALG SLLALWGGLL PPRTELPASR PPEDRLPRRP ARSGGPAPAP 60 RFPLPPPLAW DARGGSLKTF RALLTLAAGA DGPPRQSRSE PRWHVSARQP RPEESAAVHG 120 GVFWSRGLEE QVPPGFSEAQ AAAWLEAARG ARMVALERGG CGRSSNRLAR FADGTRACVR 180 YGINPEQIQG EALSYYLARL LGLQRHVPPL ALARVEARGA QWAQVQEELR AAHWTEGSW 240 SLTRWLPNLT DVWPAPWRS EDGRLRPLRD AGGELANLSQ AELVDLVQWT DLILFDYLTA 300 NFDRLVSNLF SLQWDPRVMQ RATSNLHRGP GGALVFLDNE AGLVHGYRVA GMWDKYNEPL 360 LQSVCVFRER TARRVLELHR GQDAAARLLR LYRRHEPRFP ELAALADPHA QLLQRRLDFL 420 AKHILHCKAK YGRRSGT
Seq ID NO: 543 DNA sequence
Nucleic Acid Accession ft: XM_007652.4
Coding sequence: 1..1290
11 21 31 41 51
I I I I I
ATGGCCGGCT CTGGCGCGTG GAAGCGCCTC AAATCTATGC TAAGGAAGGA TGATGCGCCG 60 CTGTTTTTAA ATGACACCAG CGCCTTTGAC TTCTCGGATG AGGCGGGGGA CGAGGGGCTT 120 TCTCβGTTCA ACAAACTTCG AGTTGTGGTG GCCGATGACG GTTCCGAAGC CCCGGAAAGG 180 CCTGTTAACG GGGCGCACCC GACCCTCCAG GCCGACGATG ATTCCTTACT GGACCAAGAC 240 TTACCTTTGA CCAACAGTCA GCTGAGTTTG AAGGTGGACT CCTGTGACAA CTGCAGCAAA 300 CAGAGAβAβA TACTGAAGCA GAGAAAGGTG AAAGCCAGGT TGACCATTGC TGCCGTTCTG 360 TACTTβCTTT TCATGATTGG AGAACTTGTA GGTGGATACA TTGCAAATAG CCTAGCAATC 420 ATGACAGATG CACTTCATAT βTTAACTβAC CTAAGCGCCA TCATACTCAC CCTGCTTGCT 480
TTGTGGCTAT CATCAAAATC ACCAACCAAA AGATTCACCT TTGGATTTCA TCGCTTAGAG 540
GTTTTGTCAG CTATGATTAG TGTGCTGTTG GTGTATATAC TTATGGGATT CCTCTTATAT 600
GAAGCTGTGC AAAGAACTAT CCATATGAAC TATGAAATAA ATGGAGATAT AATGCTCATC 660
ACCGCAGCTG TTGGAGTTGC AGTTAATGTA ATAATGGGGT TTCTGTTGAA CCAGTCTGGT 720
CACCGTCACT CCCATTCCCA CTCCCTGCCT TCAAATTCCC CTACCAGAGG TTCTGGGTGT 780
GAACGTAACC ATGGGCAGGA TAGCCTGGCA GTGAGAGCTβ CATTTGTACA TGCTTTGGGA 840
GATTTGGTAC AGAGTGTTGG TGTGCTAATA GCTGCATACA TCATACGATT CAAGCCAGAA 900
TACAAGATTG CTGATCCCAT CTGTACATAC GTATTTTCAT TACTTGTGGC TTTTACAACA 960
TTTCGAATCA TATGGGATAC AGTAGTTATA ATACTAGAAG GTGTGCCAAG CCATTTGAAT 1020
GTAGACTATA TCAAAGAAGC CTTGATGAAA ATAGAAGATG TATATTCAGT CGAAGATTTA 1080
AATATCTGGT CTCTCACTTC AGGAAAATCT ACTGCCATAG TTCACATACA GCTAATTCCT 1140
GGAAGTTCAT CTAAATGGGA GβAAβTACAG TCCAAAGCAA ACCATTTATT ATTGAACACA 1200
TTTGGCATGT ATAGATGTAC TATTCAGCTT CAGAGTTACA GβCAAGAAGT βGACAGAACT 1260
TGTGCAAATT GTCAGAGTTC TAGTCCCTGA
Seq ID NO: 544 Protein sequence
Protein Accession ft: XP_007652.1
60
120
180
Figure imgf001164_0001
240
HRHSHSHSLP SNSPTRGSGC ERNHGQDSLA VRAAFVHALG DLVQSVGVLI AAYIIRFKPE 300
YKIADPICTY VFSLLVAFTT FRIIWDTWI ILEGVPSHLN VDYIKEALMK IEDVYSVEDL 360
NIWSLTSGKS TAIVHIQLIP GSSSKWEEVQ SKANHLLLNT FGMYRCTIQL QSYRQEVDRT 420
CANCQSSSP
Seq ID NO: 545 DNA sequence
Nucleic Acid Accession ft: AB037765.1 Coding sequence: 1..2478
1 11 21 31 41 51
| 1 | 1 |1 | 1
A ITGTTTTCCG GICTTCAATGT CTTTAGAGTT GGGATCTCTT TTGTCATAAT GTGCATTTTT 60 TACATGCCAA CAGTAAACTC TTTACCAGAA CTGAGTCCTC AGAAATATTT TAGTACATTG 120 CAACCAGGAA AAGCCTCTTT AGCTTATTTT TGTCAAGCTG ATTCCCCAAG AACATCTGTA 180 TTTCTTGAAG AACTGAATGA GGCTGTTAGA CCTCTGCAGG ACTATGGAAT TTCAGTTβCC 240 AAGGTTAATT GTGTCAAAGA AGAAATATCA AGATACTGTG GAAAAGAAAA GGATTTGATG 300 AAAGCATATT TATTCAAGGG CAACATATTG CTCAGAGAAT TCCCTACTGA CACCTTGTTT 360 GATGTGAATG CCATTGTCGC CCATGTTCTC TTTGCTCTTC TTTTTAGTβA AGTGAAATAT 420 ATTACCAACC TGGAAGACCT TCAGAACATA GAAAATGCTC TGAAAβGAAA AGCAAATATT 480 ATATTCTCAT ATGTAAGAGC CATTGGAATA CCAGAGCACA GAGCAGTCAT GGAAGCCGCT 540 TTTGTβTATβ GGACTACATA CCAATTTGTC TTAACCACAG AAATTGCCCT TTTGβAAAGT 600 ATTGGCTCTG AGGATGTGGA ATATGCACAT CTCTACTTTT TTCATTGTAA ACTAGTCTTG 660 GACTTGACCC AGCAATGTAG AAGAACACTA ATGGAACAGC CATTGACTAC ACTGAACATT 720 CACCTGTTTA TTAAGACAAT GAAAGCACCT CTGTTGACTG AAGTTGCTGA AGATCCTCAA 780 CAAGTTTCAA CTGTCCATCT CCAACTGGGC TTACCACTGG TTTTTATTGT TAGCCAACAG 840 GCTACTTATG AAGCTGATAG AAGAACTGCA GAATGGGTTG CTTGG∞TCT TCTGGGAAAA 900 GCAGGAGTTC TACTCTTGTT AAGGβACTCT TTGGAAGTGA ACATTCCTCA AGATGCTAAT 960 GTβGTCTTCA AAAGAGCAGA AβAβGGAGTT CCAGTGGAAT TTTTGGTATT ACATGATGTT 1020 GATTTAATAA TATCTCATGT GGAAAATAAT ATGCACATTG AGGAAATACA AGAAGATGAA 1080 GACAATGACA TGGAAGGTCC AGATATAGAT GTTCAGGATG ATGAAGTGGC AGAAACTGTT 1140 TTCAGAGATA GGAAGAGAAA ATTACCTTTG GAACTTACAG TGGAACTAAC AGAAGAAACA 1200 TTTAATGCAA CAGTGATGGC TTCTGACAGC ATAGTACTCT TCTATGCTGG TTGGCAAβCA 1260 GTATCCATGG CATTTTTGCA ATCCTATATT GATGTGGCAG TTAAACTGAA AββCACATCT 1320 ACTATGCTTC TTACTAβAAT AAACTGTGCA GATTGGTCTG ATGTATGTAC TAAβCAAAAT 1380 GTTACTGAAT TTCCTATCAT AAAGATGTAC AAGAAAGGCG AGAACCCAGT ATCTTATGCT 1440 GGAATGTTAG GAACCGAAGA TCTCCTAAAA TTTATCCAGC TCAACA6GAT TTCATATCCA 1500 GTGAATATAA CATCGATCCA AGAAGCAGAA GAATATTTAA GTβββGAATT ATATAAAGAC 1560 CTCATCTTGT ATTCTACTβT GTCAGTATTG GGACTATTTA GTCCAACCAT GAAAACAGCA 1620 AAAGAAGATT TTAGTGAAGC AGGAAACTAC CTAAAAGGAT ATGTTATCAC TGGAATTTAT 1680 TCTGAAβAAG ATGTTTTGCT ACTGTCAACC AAATATGCTG CAAGTCTTCC AGCCCTGCTG 1740 CTTGCCAGAC ACACAGAAGG CAAAATAGAG AGCATCCCAC TAGCTAGCAC ACATGCACAA 1800 GACATAGTTC AAATAATAAC AGATGCACTA CTGGAAATGT TTCCGGAAAT CACTGTGGAA 1860 AATCTTCCCA GTTATTTCAG ACTTCAGAAA CCATTATTGA TTTTGTTCAG TGATGGCACT 1920 GTAAATCCTC AGTATAAAAA AGCAATATTG ACACTGGTAA AGCAGAAATA CTTGGATTCA 1980 TTTACTCCAT GCTβGTTAAA TCTAAAGAAT ACTCCAGTGG GGAGAGGAAT CTTGAGββCA 2040 TATTTTGATC CTCTGCCTCC CCTTCCTCTT CTTGTTTTGG TGAATCTGCA TTCAGGTGGC 2100 CAAGTATTTG CATTTCCTTC AGACCAGGCT ATAATTGAAG AAAACCTTGT ATTGTβGCTG 2160 AAGAAATTAG AAβCA∞ACT AGAAAATCAT ATCACAATTT TACCTGCTCA AGAATGGAAA 2220 CCTCCTCTTC CAGCTTATGA . TTTTCTAAGT ATGATAGATG CCGCAACATC TCAACGTGGC 2280 ACTAGGAAAG TTCCCAAGTG TATGAAAGAA ACAGATGTGC AββAβAATGA TAAGGAACAA 2340 CATGAAGATA AATCGGCAGT CAGAAAAGAA CCGATTGAAA CTCTGAGAAT AAAGCATTGG 2400 AATAGAAGTA ATTGGTTTAA . AGAAGCAGAA AAATCATTTA GACGTGATAA AGAGTTAGβA 2460 TGCTCAAAAG TGAACTAA
Seq ID NO: 546 Protein sequence Protein Accession ff: BAA92582.1
11 31 MFSGFNVFRV GISFVIMCIF YMPTVNSLPE LSPQKYFSTL QPβKASLAYF CQADSPRTSV 60 FLEELNEAVR PLQDYGISVA KVNCVKEEIS RYCGKEKDLM KAYLFKGNIL LREFPTDTLF 120 DVNAIVAHVL FALLFSEVKY ITNLEDLQNI ENALKGKANI IFSYVRAIGI PEHRAVMEAA 180 FVYGTTYQFV LTTEIALLES IGSEDVEYAH LYFFHCKLVL DLTQQCRRTL MEQPLTTLNI 240 HLFIKTMKAP LLTEVAEDPQ QVSTVHLQLG LPLVFIVSQQ ATYEADRRTA EWVAWRLLGK 300 AGVLLLLRDS LEVNIPQDAN WFKRAEEGV PVEFLVLHDV DLIISHVENN MHIEEIQEDE 360 DNDMEGPDID VQDDEVAETV FRDRKRKLPL ELTVELTEET FNATVMASDS IVLFYAGWQA 420 VSMAFLQSYI DVAVKLKGTS TMLLTRINCA DWSDVCTKQN VTEFPIIKMY KKGENPVSYA 480 GMLGTEDLLK FIQLNRISYP VNITSIQEAE EYLSGELYKD LILYSSVSVL βLFSPTMKTA 540 KEDFSEAGNY LKGYVITGIY SEEDVLLLST KYAASLPALL LARHTEGKIE SIPLASTHAQ 600 DIVQIITDAL LEMFPEITVE NLPSYFRLQK PLLILFSDGT VNPQYKKAIL TLVKQKYLDS 660 FTPCWLNLKN TPVGRGILRA YFDPLPPLPL LVLVNLHSββ QVFAFPSDQA IIEENLVLWL 720 KKLEAGLENH ITILPAQEWK PPLPAYDFLS MIDAATSQRβ TRKVPKCMKE TDVQENDKEQ 780 HEDKSAVRKE PIETLRIKHW NRSNWFKEAE KSFRRDKELβ CSKVN
Seq ID NO: 547 DNA sequence
Nucleic Acid Acceεεion ft: NM_033102.l
Coding sequence: 1..1662
11 21 31 41 51
I I I I
ATGGTCCAGA 6GCTGT6GGT GAGCCβCCTβ CTGCGGCACC G 1GAAAGCCCA GCTCTTCCTG 60 GTCAACCTGC TAACCTTTββ CCTββAβCTG TGTTTG6CCG CAGGCATCAC CTATGTGCCG 120 CCTCTGCTGC TGGAAGTGGG GGTAGAGGAG AAGTTCATβA CCATGGTGCT GGGCATTGGT 180 CCAGTGCTGG GCCTGGTCTG TGTCCCGCTC CTAGGCTCAG CCAGTGACCA CTGGCGTGGA 240 CGCTATCβCC GCCGCCGGCC CTTCATCTGG GCACTGTCCT TGGGCATCCT GCTGAGCCTC 300 TTTCTCATCC CAAGGGCCGG CTGGCTAGCA GGGCTGCTGT GCCCGGATCC CAGGCCCCTG 360 GAGCTGGCAC TGCTCATCCT GGGCGTGGGG CTGCTGGACT TCTGTGGCCA G6TGTGCTTC 420 ACTCCACTGG AGGCCCTGCT CTCTGACCTC TTCCGGGACC CGGACCACTG TCGCCAGGCC 480 TACTCTGTCT ATGCCTTCAT GATCAGTCTT GβGGGCTGCC TGGGCTACCT CCTGCCTβCC 540 ATTGACTGGG ACACCAGTGC CCTGβCCCCC TACCTGββCA CCCAGGAGGA GTGCCTCTTT 600 GβCCTCCTCA CCCTCATCTT CCTCACCTGC βTAβCAβCCA CACTGCTGGT GGCTGAGGAG 660 GCAGCGCTGβ GCCCCACCGA GCCAGCAGAA GGGCTGTCGG CCCCCTCCTT GTCGCCCCAC 720 TGCTGTCCAT GCCGGGCCCG CTTG6CTTTC CGGAACCTGβ βcecccTGCT TCCCCGβCTβ 780 CACCAGCTGT GCTCCCβCAT βCCCCGCACC CTGCGCCGGC TCTTCβTβec TGAGCTGTGC 840 AGCTGGATGβ CACTCATGAC CTTCACGCTG TTTTACACGG ATTTCGTGGG CGAGββGCTG 900 TACCAGGGCG TGCCCAGAGC TβAβCCGGβC ACCGAGGCCC GCAβACACTA TβATGAAGGC 960 GTTCGGATGG GCAβCCTβGG GCTβTTCCTG CAGTβCβCCA TCTCCCTGGT CTTCTCTCTG 1020 GTCATGGACC GGCTββTGCA GCGATTCGGC ACTCGAGCAG TCTATTTGGC CAGTβTββCA 1080 GCTTTCCCTG TGGCTGCCGβ TGCCACATGC GTGTCCCACA GTGTGGCCGT ββTβACAβCT 1140 TCAGCCGCCC TCACCGGGTT CACCTTCTCA GCCCTβCAβA TCCTGCCCTA CACACTβGCC 1200 TCCCTCTACC ACCGGβAGAA GCAβGTGTTC CTβCCCAAAT ACCGAGGGβA CACTGGAGGT 1260 GCTAGCAGTG AGGACAGCCT GATGACCAGC TTCCTGCCAG βCCCTAAβCC TGGAβCTCCC 1320 TTCCCTAATG GACACGTGGG TGCTββAGGC AGTGGCCTβC TCCCACCTCC ACCCGCCCTC 1380 TGCGG∞CCT CTGCCTGTGA TGTCTCCGTA CGTGTGGTGG TGGGTGAGCC CACCGAGGCC 1440 AGGGTGGTTC CGGGCCGGGG CATCTGCCTG GACCTCGCCA TCCTGGATAG TGCCTTCCTG 1500 CTGTCCCAGG TGGCCCCATC CCTGTTTATG GGCTCCATTG TCCAGCTCAG CCAGTCTGTC 1560 ACTGCCTATA TGGTGTCTGC CGCAGGCCTG GGTCTGGTCG CCATTTACTT TGCTACACAG 1620 GTAGTATTTG ACAAGAβCGA CTTGGCCAAA TACTCAGCGT GA
Seq ID NO: 548 Protein sequence Protein Accession ft: NP 149093.1
11 21 31 41 51
I I I I I
MVQRLWVSRL LRHRKAQLLL VNLLTFGLEV CLAAGITYVP PLLLEVGVEE KFMTMVLGIG 60 PVLGLVCVPL LGSASDHWRG RYGRRRPFIW ALSLGILLSL FLIPRAGWLA GLLCPDPRPL 120 ELALLILGVG LLDFCGQVCF TPLEALLSDL FRDPDHCRQA YSVYAFMISL GGCLGYLLPA 180 IDWDTSALAP YLGTQEECLF GLLTLIFLTC VAATLLVAEE AALGPTEPAE GLSAPSLSPH 240 CCPCRARLAF RNLGALLPRL HQLCCRMPRT LRRLFVAELC SWMALMTFTL FYTDFVGEGL 300 YQGVPRAEPG TEARRHYDEG VRMGSLGLFL QCAISLVFSL VMDRLVQRFG TRAVYLASVA 360 AFPVAAGATC LSHSVAWTA SAALTGFTFS ALQILPYTLA SLYHREKQVF LPKYRGDTGG 420 ASSEDSLMTS FLPGPKPGAP FPNGHVGAGG SGLLPPPPAL CGASACDVSV RVWGEPTEA 480 RWPGRGICL DLAILDSAFL LSQVAPSLFM GSIVQLSQSV TAYMVSAAGL GLVAIYFATQ 540 WFDKSDLAK YSA
Seq ID NO: 549 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..1389
60
120
Figure imgf001165_0001
180
GGGTTTCCTT TGGGAATATT GCTTTTATTC TGGGTTTCAT ATGTTACGGA CTTTTCCCTT 240
GTTTTATTGA TAAAAβGAGG GGCCCTCTCT GGAACAGATA CCTACCAGTC TTTGGTCAAT 300
AAAACTTTCG GCTTTCCAGG GTATCTGCTC CTCTCTGTTC TTCAGTTTTT βTATCCTTTT 360
ATAGCAATGA TAAGTTACAA TATAATAGCT GGAGATACTT TGAGCAAAGT TTTTCAAAGA 420
ATCCCAGGAG TTGATCCTGA AAACGTGTTT ATTGGTCGCC ACTTCATTAT TGGACTTTCC 480
ACAGTTACCT TTACTCTGCC TTTATCCTTG TACCGAAATA TAGCAAAGCT TGGAAAGGTC 540
TCCCTCATCT CTACAGGTTT AACAACTCTG ATTCTTGGAA TTGTAATGGC AAGGGCAATT 600
TCACTGGGTC CACACATACC AAAAACAGAA GACGCTTGGG TATTTGCAAA GCCCAATGCC 660
ATTCAAGCGG TCGβGβTTAT GTCTTTTGCA TTTATTTGCC ACCATAACTC CTTCTTAGTT 720 TACAGTTCTC TAGAAGAACC CACAGTAGCT AAGTGGTCCC GCCTTATCCA TATGTCCATC 780
GTGATTTCTG TATTTATCTG TATATTCTTT GCTACATGTG GATACTTGAC ATTTACTβGC 840
TTCACCCAAG GGGACTTATT TGAAAATTAC TGCAGAAATG ATGACCTGGT AACATTTGGA 900
AGATTTTGTT ATGGTβTCAC TGTCATTTTG ACATACCCTA TGGAATGCTT TGTGACAAGA 960
GAβGTAATTG CCAATGTGTT TTTTGGTGGG AATCTTTCAT CGGTTTTCCA CATTGTTGTA 1020
ACAGTGATGG TCATCACTGT AGCCACGCTT GTGTCATTGC TGATTβATTG CCTCGβGATA 1080
GTTCTAGAAC TCAATGGTGT GCTCTGTGCA ACTCCCCTCA TTTTTATCAT TCCATCAGCC 1140
TGTTATCTGA AACTGTCTGA AGAACCAAGG ACACACTCCG ATAAGATTAT GTCTTβTβTC 1200
ATGCTTCCCA TTGGTGCTGT GGTGATGGTT TTTGGATTCG TCATGGCTAT TACAAATACT 1260
CAAGACTGCA CCCATβββCA GGAAATGTTC TACTGCTTTC CTGACAATTT CTCTCTCACA 1320
AATACCTCAG AGTCTCATGT TCAGCAGACA ACACAACTTT CTACTTTAAA TATTAGTATC 1380 TTTCAATGA
Seq ID NO: 550 Protein sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQRDLDDRE TLVSEHEYKE KTCQSAALFN WNSIIGSGI IGLPYSMKQA 60 GFPLGILLLF WVSYVTDFSL VLLIKGGALS GTDTYQSLVN KTFGFPGYLL LSVLQFLYPF 120
IAMISYNIIA GDTLSKVFQR IPGVDPENVF IGRHFIIGLS TVTFTLPLSL YRNIAKLGKV 180
SLISTGLTTL ILGIVMARAI SLGPHIPKTE DAWVFAKPNA IQAVGVMSFA FICHHNSFLV 240
YSSLEEPTVA KWSRLIHMSI VISVFICIFF ATCCYLTFTG FTQGDLFENY CRNDDLVTFG 300
RFCYGVTVIL TYPMECFVTR EVIANVFFGG NLSSVFHIW TVMVITVATL VSLLIDCLGI 360 VLELNGVLCA TPLIFIIPSA CYLKLSEEPR THSDKIMSCV MLPIGAWMV FGFVMAITNT 420 QDCTHGQEMF YCFPDNFSLT NTSESHVQQT TQLSTLNISI FQ
Seq ID NO: 551 DNA sequence Nucleic Acid Accession #: Eos sequence Coding sequence: 1..1284
1 11 21 31 41 51
I I I I I I
ATGGGCTACC AGAGGCAGGA GCCTGTCATC CCGCCGCAGA GAGGATTGCC TTATTCAATG 60
AAGCAAGCTG GGTTTCCTTT GGGAATATTG CTTTTATTCT GGGTTTCATA TGTTACAGAC 120
TTTTCCCTTG TTTTATTGAT AAAAGGAGGG GCCCTCTCTG GAACAβATAC CTACCAGTCT 180
TTGGTCAATA AAACTTTCGG CTTTCCAGGG TATCTGCTCC TCTCTGTTCT TCAGTTTTTG 240
TATCCTTTTA TAGCAATGAT AAGTTACAAT ATAATAGCTG GAGATACTTT GAGCAAAGTT 300
TTTCAAAGAA TCCCAGGAGT TGATCCTGAA AACGTGTTTA TTGGTCGCCA CTTCATTATT 360
GGACTTTCCA CAGTTACCTT TACTCTGCCT TTATCCTTGT ACCGAAATAT AGCAAAGCTT 420
GGAAAGGTCT CCCTCATCTC TACAGGTTTA ACAACTCTGA TTCTTGGAAT TGTAATGGCA 480
AGGGCAATTT CACTGGGTCC ACACATACCA AAAACAGAAG ACGCTTGGGT ATTTβCAAAG 540
CCCAATGCCA TTCAAGCGGT CGGGβTTATG TCTTTTGCAT TTATTTGCCA CCATAACTCC 600
TTCTTAGTTT ACAGTTCTCT AGAAGAACCC ACAGTAGCTA AGTGGTCCCG CCTTATCCAT 660
ATGTCCATCG TGATTTCTGT ATTTATCTGT ATATTCTTTG CTACATGTGG ATACTTGACA 720
TTTACTGGCT TCACCCAAGG GGACTTATTT GAAAATTACT GCAGAAATGA TGACCTGβTA 780
ACATTTGGAA GATTTTGTTA TGGTGTCACT GTCATTTTβA CATACCCTAT GGAATGCTTT 840
GTGACAAGAG AGGTAATTGC CAATGTGTTT TTTGGTGGGA ATCTTTCATC GGTTTTCCAC 900
ATTGTTGTAA CAGTGATGGT CATCACTGTA GCCACGCTTG TGTCATTGCT βATTGATTGC 960
CTCGGGATAG TTCTAGAACT CAATGGTGTG CTCTGTGCAA CTCCCCTCAT TTTTATCATT 1020
CCATCAGCCT GTTATCTGAA ACTGTCTGAA GAACCAAGGA CACACTCCGA TAAGATTATG 1080
TCTTGTGTCA TGCTTCCCAT TGGTGCTGTG GTGATGGTTT TTGGATTCGT CATGGCTATT 1140
ACAAATACTC AAGACTGCAC CCATGGGCAG GAAATGTTCT ACTGCTTTCC TGACAATTTC 1200
TCTCTCACAA ATACCTCAGA GTCTCATGTT CAGCA6ACAA CACAACTTTC TACTTTAAAT 1260 ATTAGTATCT TTCAACTCGA GTAA
Seq ID NO: 552 Protein sequence Protein Accession #: Eos sequence
1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQRGLPYSM KQAGFPLGIL LLFWVSYVTD FSLVLLIKGG ALSGTDTYQS 60
LVNKTFGFPG YLLLSVLQFL YPFIAMISYN IIAGDTLSKV FQRIPGVDPE NVFIGRHFII 120
GLSTVTFTLP LSLYRNIAKL GKVSLISTGL TTLILGIVMA RAISLGPHIP KTEDAWVFAK 180
PNAIQAVGVM SFAFICHHNS FLVYSSLEEP TVAKWSRLIH MSIVISVFIC IFFATCβYLT 240
FTGFTQGDLF ENYCRNDDLV TFGRFCYGVT VILTYPMECF VTREVIANVF FGGNLSSVFH 300
IWTVMVITV ATLVSLLIDC LGIVLELNGV LCATPLIFII PSACYLKLSE EPRTHSDKIM 360
SCVMLPIGAV VMVFGFVMAI TNTQDCTHGQ EMFYCFPDNF SLTNTSESHV QQTTQLSTLN 420 ISIFQLE
Seq ID NO: 553 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..1203
1 11 21 31 41 51
I I I I I I
ATGGGCTACC AGAGGCAGGA GCCTGTCATC CCGCCGCAGT TTTCCCTTGT TTTATTGATA 60
AAAGGAGGGG CCCTCTCTGG AACAGATACC TACCAGTCTT TGβTCAATAA AACTTTCGGC 120
TTTCCAGGGT ATCTGCTCCT CTCTGTTCTT CAGTTTTTGT ATCCTTTTAT AGCAATGATA 180
AGTTACAATA TAATAGCTGG AGATACTTTG AGCAAAGTTT TTCAAAGAAT CCCAGGAGTT 240
GATCCTGAAA ACGTGTTTAT TGGTCGCCAC TTCATTATTG βACTTTCCAC AGTTACCTTT 300
ACTCTGCCTT TATCCTTGTA CCGAAATATA GCAAAGCTTβ GAAAGGTCTC CCTCATCTCT 360
ACAGGTTTAA CAACTCTGAT TCTTGGAATT GTAATβeCAA GGGCAATTTC ACTGGGTCCA 420
CACATACCAA AAACAβAAGA CGCTTGGGTA TTTGCAAAGC CCAATGCCAT TCAAGCGGTC 480 GGGGTTATGT CTTTTGCATT TATTTGCCAC CATAACTCCT TCTTAβTTTA CAGTTCTCTA 540
GAAGAACCCA CAGTAGCTAA GTGGTCCCGC CTTATCCATA TGTCCATCGT GATTTCTGTA 600
TTTATCTGTA TATTCTTTGC TACATGTGGA TACTTGACAT TTACTGβCTT CACCCAAGGG 660
GACTTATTTG AAAATTACTG CAGAAATGAT GACCTGGTAA CATTTGGAAG ATTTTGTTAT 720
GβTGTCACTG TCATTTTGAC ATACCCTATG βAATβCTTTβ TGACAAGAGA GGTAATTGCC 780
AATGTGTTTT TTGGTGGGAA TCTTTCATCG GTTTTCCACA TTGTT6TAAC AGTGATGGTC 840
ATCACTGTAG CCACGCTTGT GTCATTGCTG ATTGATTGCC TCGβGATAGT TCTAGAACTC 900
AATGβTβTGC TCTGTGCAAC TCCCCTCATT TTTATCATTC CATCAGCCTG TTATCTGAAA 960
CTβTCTGAAG AACCAAGGAC ACACTCCGAT AAGATTATGT CTTGTGTCAT GCTTCCCATT 1020
GGTβCTGTGG TGATGGTTTT TGGATTCGTC ATGGCTATTA CAAATACTCA AGACTGCACC 1080
CATGGGCAGG AAATGTTCTA CTGCTTTCCT CACAATTTCT CTCTCACAAA TACCTCACAG 1140
TCTCATGTTC AGCAβACAAC ACAACTTTCT ACTTTAAATA TTAGTATCTT TCAACTCGAG 1200 TAA
Seq ID NO: 554 Protein sequence Protein Accession # : Eos sequence
1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQFSLVLLI KGGALSGTDT YQSLVNKTFG FPGYLLLSVL QFLYPFIAMI 60
SYNIIAGDTL SKVFQRIPGV DPENVFIGRH FIIGLSTVTF TLPLSLYRNI AKLGKVSLIS 120
TGLTTLILGI VMARAISLGP HIPKTEDAWV FAKPNAIQAV GVMSFAFICH HNSFLVYSSL 180
EEPTVAKWSR LIHMSIVISV FICIFFATCG YLTFTGFTQG DLFENYCRND DLVTFGRFCY 240
GVTVILTYPM ECFVTREVIA NVFFGGNLSS VFHIWTVMV ITVATLVSLL IDCLGIVLEL 300
NGVLCATPLI FIIPSACYLK LSEEPRTHSD KIMSCVMLPI GA MVFGFV MAITNTQDCT 360 HGQEMFYCFP DNFSLTNTSE SHVQQTTQLS TLNISIFQLE
Seq ID NO: 555 DNA sequence Nucleic Acid Accession ft: Eos sequence Coding sequence: 1..1140
1 11 21 31 41 51
A ITGGGCTACC AIGAGGCAGGA GICCTGTCATC CICGCCGCAGG TICAATAAAAC TITTCGGCTTT 60
CCAGGGTATC TGCTCCTCTC TGTTCTTCAG TTTTTGTATC CTTTTATAGC AATGATAAGT 120
TACAATATAA TAGCTGGAGA TACTTTGAGC AAAGTTTTTC AAAGAATCCC AGGAGTTGAT 180
CCTGAAAACG TGTTTATTGG TCGCCACTTC ATTATTGGAC TTTCCACAGT TACCTTTACT 240
CTGCCTTTAT CCTTGTACCG AAATATAGCA AAGCTTGGAA AGGTCTCCCT CATCTCTACA 300
GGTTTAACAA CTCTGATTCT TGGAATTGTA ATGGCAAGGG CAATTTCACT GGGTCCACAC 360
ATACCAAAAA CAGAAGACGC TTGβGTATTT GCAAAGCCCA ATβCCATTCA AGCGGTCGGG 420
GTTATGTCTT TTGCATTTAT TTGCCACCAT AACTCCTTCT TAGTTTACAG TTCTCTAGAA 480
GAACCCACAG TAGCTAAGTG GTCCCGCCTT ATCCATATGT CCATCGTGAT TTCTGTATTT 540
ATCTGTATAT TCTTTGCTAC ATGTGGATAC TTGACATTTA CTGGCTTCAC CCAAGGGGAC 600
TTATTTGAAA ATTACTGCAG AAATGATGAC CTββTAACAT TTGGAAGATT TTGTTATGGT 660
GTCACTGTCA TTTTGACATA CCCTATGGAA TβCTTTβTGA CAAGAGAGGT AATTGCCAAT 720
GTGTTTTTTG GTGGGAATCT TTCATCGGTT TTCCACATTG TTGTAACAGT GATGGTCATC 780
ACTGTAGCCA CCCTTGTGTC ATTGCTGATT βATTGCCTCG GGATAGTTCT AGAACTCAAT 840
GGTGTGCTCT GTGCAACTCC CCTCATTTTT ATCATTCCAT CAGCCTGTTA TCTGAAACTG 900
TCTGAAGAAC CAAGGACACA CTCCGATAAG ATTATGTCTT GTGTCATGCT TCCCATTGGT 960
GCTGTGGTGA TGGTTTTTGG ATTCGTCATG GCTATTACAA ATACTCAAGA CTGCACCCAT 1020
GGGCAGGAAA TGTTCTACTG CTTTCCTGAC AATTTCTCTC TCACAAATAC CTCAGAGTCT 1080 CATGTTCAGC AGACAACACA ACTTTCTACT TTAAATATTA GTATCTTTCA ACTCGAGTAA
Seq ID NO: 556 Protein sequence Protein Accession #: Eos sequence
1 11 21 31 41 51
I I I I I I
MGYQRQEPVI PPQVNKTFGF PGYLLLSVLQ FLYPFIAMIS YNIIAGDTLS KVFQRIPGVD 60
PENVFIGRHF IIGLSTVTFT LPLSLYRNIA KLGKVSLIST GLTTLILGIV MARAISLGPH 120
IPKTEDAWVF AKPNAIQAVG VMSFAFICHH NSFLVYSSLE EPTVAKWSRL IHMSIVISVF 180
ICIFFATCGY LTFTGFTQGD LFENYCRNDD LVTFGRFCYG VTVILTYPME CFVTREVIAN 240
VFF6GNLSSV FHIWTVMVI TVATLVSLLI DCLGIVLELN GVLCATPLIF IIPSACYLKL 300
SEEPRTHSDK IMSCVMLPIG AWMVFGFVM AITNTQDCTH GQEMFYCFPD NFSLTNTSES 360 HVQQTTQLST LNISIFQLE
Seq ID NO: 557 DNA sequence Nucleic Acid Accession ft: XM_057188.1 Coding sequence: 769..4269
1 11 21 31 41 51
I I I I I I
ATGGGATTGC CTCTCCCTCT CACTCTGGGC TTCTGTCCCA CTCTTATCTT AGTGTCAGTC 60
CTCCCCCAAG TCTGTGTCCC TCTCTCTCCC CTAAATCTCT GGCCCCTCCT TTCTGAGTTC 120
CTGCCCTTCC CCCAATTCTT TGGTTTTTGC ATCCCCCTCT GCCCCTTGCC TCAGTCAAGT 180
CTCCCCTGTG TGTCTCTCTC CCCCCGGCCC GGACCTCTGC ACCCCCCAGG TCGCTGTCCC 240
TCTGTCCCCT TATCGCGGCC TGGβACCCGC CCTCTCCCCG CCTCCCGCTT TGGCGTCTCC 300
AAGACTCCCC GCCCCCCAGA CCTCGCCCCG CCCCAGGCTA GGCTGGAAAG TGGAGGATCC 360
GGTTTGCTCT GGGCGGGTCT GGAAGCAGAG CCGGCGGAGG GAGCCCCGGG GCCCTββGCT 420
GCAGβAββTT GCGGCGGCCG CGGCAGCATG GTGGTGCCGβ AGAAGGAGCA GAGCTGGATC 480
CCCAAGATCT TCAAGAAGAA GACCTGCACG ACGTTCATAG TTGACTCCAC AGATCCGGGG 540
GATGGGGTCT CGCTCTATTG CCCAGGCTGT TCTCAAACTC CTGGGCTCAA GCAGTCCTTC 600
TβCCTTβACC TCCCAAAGTG CTTGGATTGT GCCCAβCCGT CCTTGAAGTT TTGCTCAGAA 660
GAGCAAACTT TCTGGGAAGT AGCTGCAGGT GTTβGAAGTA GCTGCAGGGG AACTAGGGGA 720 TTCAAGGATG GAGCTGAAAT GGGTGAACGG ACAAAGTCGG TAAACTGAAT GGAGGATGCC 780
TTCGGββCAG CCGTGGTGAC CGTGTGGGAC AβCGATGCAC ACACCACGGA GAAGCCCACC 840 βATβCCTACG GAGAGCTGβA CTTCACGGGG GCCGGCCβCA AGCACAGCAA TTTCCTCCGβ 900
CTCTCTGACC GAACGβATCC AGCTGCAGTT TATAGTCTGG TCACACGCAC ATGGGGCTTC 960
CGTGCCCCGA ACCTGGTGβT GTCAGTGCTG GGGGGATCGG GGGGCCCCGT CCTCCAGACC 1020
TGGCTGCAGG ACCTGCTGCG TCGTββGCTG GTGCGGGCTβ CCCAGAGCAC AGGAGCCTβG 1080
ATTGTCACTG GGGβTCTβCA CACCGGCATC GGCCGGCATG TTGGTGTGGC TGTACGGβAC 1140
CATCAβATGG CCAGCACTGG GGGCACCAAG GTGGTGGCCA TGβGTGTGGC CCCCTGGGGT 1200
GTGGTCCGGA ATAGAGACAC CCTCATCAAC CCCAAGGGCT CGTTCCCTGC GAGGTACCGG 1260
TGGCGCGGTG ACCCGGAβGA CGGGGTCCAG TTTCCCCTGβ ACTACAACTA CTCGGCCTTC 1320
TTCCTGGTGG ACGACGβCAC ACACGGCTGC CTGβGGGβCC AGAACCGCTT CCGCTTGCGC 1380
CTGGAGTCCT ACATCTCACA GCAGAAGACG GGCGTGGGAG GGACTGGAAT TGACATCCCT 1440
GTCCTGCTCC TCCTGATTGA TGGTβATGAG AAGATGTTGA CGCGAATAGA GAACGCCACC 1500
CAGβCTCAGC TCCCATGTCT CCTCGTGGCT GGCTCAGGGG GAGCTGCGGA CTGCCTGGGG 1560
GAβACCCTGG AAGACACTCT GGCCCCAGGG AGTGGGGGAβ CCAGGCAAGG CGAAGCCCGA 1620
GATCGAATCA GGCGTTTCTT TCCCAAAGGG GACCTTGAGG TCCTGCAGGC CCAββTGGAG 1680
AGGATTATGA CCCGGAAGGA GCTCCTGACA GTCTATTCTT CTGAGGATGG GTCTGAGGAA 1740
TTCGAGACCA TAGTTTTGAA GGCCCTTGTG AAGGCCTGTβ GGAGCTCGGA GGCCTCAGCC 1800
TACCTGGATG AGCTGCGTTT GGCTGTGGCT TGGAACCGCG TGGACATTGC CCAGAGTGAA 1860
CTCTTTCGGG GGGACATCCA ATGGCGβTCC TTCCATCTCG AAGCTTCCCT CATGGACGCC 1920
CTGCTGAATG ACCGGCCTGA GTTC6TGCGC TTGCTCATTT CCCACGGCCT CAGCCTGGGC 1980
CACTTCCTGA CCCCGATGCG CCTGGCCCAA CTCTACAGCG CGGCGCCCTC CAACTCGCTC 2040
ATCCGCAACC TTTTGGACCA GGCGTCCCAC AGCGCAGGCA CCAAAGCCCC AGCCCTAAAA 2100
GGGGGAGCTG CGGAGCTCCG GCCCCCTGAC GTGGGβCATβ TGCTGAGGAT GCTGCTGGGG 2160
AAGATGTGCG CβCCGAGGTA CCCCTCCGGG GGCGCCTβGG ACCCTCACCC AGGCCAGGGC 2220
TTCGGGGAGA GCATβTATCT GCTCTCGGAC AAββCCACCT CGCCGCTCTC GCTGGATGCT 2280
GGCCTCGGGC AGGCCCCCTβ GAG∞ACCTG CTTCTTTGGG CACTGTTGCT GAACAGGGCA 2340
CAGATGGCCA TGTACTTCTG GGAGATGGGT TCCAATGCAG TTTCCTCAGC TCTTGGGGCC 2400
TGTTTGCTGC TCCGGGTGAT GGCACGCCTG GAGCCTGACG CTGAGGAGGC AGCACGGAGG 2460
AAAGACCTGG CGTTCAAGTT TGAGGGGATG GGCGTTGACC TCTTTGGCGA GTGCTATCGC 2520
AGCAβTGAGG TGAGGGCTGC CCGCCTCCTC CTCCGTCGCT GCCCGCTCTG GGGGGATGCC 2580
ACTTGCCTCC ACCTGGCCAT GCAAGCTGAC GCCCGTGCCT TCTTTGCCCA GGATGGGGTA 2640
CAGTCTCTGC TGACACAGAA GTGGTGGGGA GATATGGCCA GCACTACACC CATCTGGGCC 2700
CTGGTTCTCG CCTTCTTTTG CCCTCCACTC ATCTACACCC GCCTCATCAC CTTCAGGAAA 2760
TCAGAAGAGG AGCCCACACG GGAGGAGCTA GAGTTTGACA TGGATAGTβT CATTAATGGG 2820
GAAGGGCCTG TCGGGACGGC GGACCCAGCC GAGAAGACGC CGCTGGGGGT CCCGCGCCAG 2880
TCGGGCCGTC CGGGTTGCTG CGGGGGCCGC TGCGGGβGGC GCCGGTGCCT ACGCCGCTGG 2940
TTCCACTTCT GGGGCGCGCC GGTGACCATC TTCATGGβCA ACGTGGTCAG CTACCTGCTG 3000
TTCCTGCTGC TTTTCTCGCG GGTGCTGCTC GTGGATTTCC AGCCGGCGCC GCCCGGCTCC 3060
CTGGAGCTGC TGCTCTATTT CTGGGCTTTC ACGCTGCTGT GCGAGGAACT GCβCCAGGGC 3120
CTGAGCGGAG GCGGGGGCAG CCTCGCCAGC GGGGGCCCCG GGCCTGGCCA TGCCTCACTG 3180
AGCCAGCGCC TGCGCCTCTA CCTCGCCGAC AGCTGGAACC AGTβCGACCT AGTGGCTCTC 3240
ACCTGCTTCC TCCTGGGCGT GGGCTβCCGG CTGACCCCGG GTTTGTACCA CCTGGGCCβC 3300
ACTCTCCTCT GCATCGACTT CATGGTTTTC ACGGTGCGGC TGCTTCACAT CTTCACGGTC 3360
AACAAACAGC TGGGGCCCAA GATCGTCATC CTGAGCAAGA TGATGAAGGA CGTGTTCTTC 3420
TTCCTCTTCT TCCTCGGCGT GTGGCTGGTA GCCTATGGCG TGGCCACGGA GGGGCTCCTG 3480
AGGCCACGGG ACAGTβACTT CCCAAβTATC CTGCGCCGCβ TCTTCTACCG TCCCTACCTG 3540
CAGATCTTCG GGCAGATTCC CCAGβAββAC ATGGACGTGG CCCTCATGGA GCACAGCAAC 3600
TGCTCGTCGG AGCCCGGCTT CTGGGCACAC CCTCCTGGGG CCCAGGCGGG CACCTGCCTC 3660
TCCCAGTATG CCAACTGGCT GGTGGTGCTG CTCCTCGTCA TCTTCCTGCT CβTGGCCAAC 3720
ATCCTGCTGG TCAACTTGCT CATTGCCATG TTCAGTTACA CATTCGGCAA AGTACAGGGC 3780
AACAGCGATC TCTACTGGAA GGCGCAGCGT TACCGCCTCA TCCGGGAATT CCACTCTCGG 3840
CCCGCGCTGG CCCCGCCCTT TATCGTCATC TCCCACTTGC GCCTCCTGCT CAGGCAATTG 3900
TGCAGβCGAC CCCGGAβCCC CCAGCCGTCC TCCCCGGCCC TCβAGCATTT CCGGGTTTAC 3960
CTTTCTAAGG AAβCCβAβCβ βAAβCTGCTA ACGTββGAAT CGGTGCATAA GGAGAACTTT 4020
CTGCTGGCAC GCGCTAGGGA CAAGCGGGAG AGCGACTCCG AGCGTCTGAA GCGCACGTCC 4080
CAGAAGGTGG ACTTGCCACT GAAACAGCTG GGACACATCC GCGAGTACGA ACAGCGCCTG 4140
AAAGTGCTGG AGCGGGAGGT CCAGCAGTGT AGCCGCGTCC TGGGGTGGGT GGCCGAGGCC 4200
CTGAGCCGCT CTGCCTTGCT GCCCCCAGGT GGGCCGCCAC CCCCTGACCT GCCTGGGTCC 4260
AAAGACTGAG CCCTGCTGGC GGACTTCAAG GAGAAGCCCC CACAGGGGAT TTTGCTCCTA 4320
GAGTAAGGCT CATCTGGGCC TCGGCCCCCG CACCTGGTGG CCTTGTCCTT GAGGTGAGCC 4380
CCATGTCCAT CTGGGCCACT GTCAGGACCA CCTTTGGGAG TGTCATCCTT ACAAACCACA 4440
GCATGCCCβG CTCCTCCCAG AACCAGTCCC AGCCTGGGAG 6ATCAAGGCC TGGATCCCGG 4500
GCCGTTATCC ATCTGGAGGC TGCAGGGTCC TTGGGGTAAC AGGGACCACA GACCCCTCAC 4560
CACTCACAGA TTCCTCACAC TGGGGAAATA AAGCCATTTC AGAGGAAAAA AAAAAAAAAA 4620 AAAAAAAAAA AAAAAAAAAA A
Seq ID NO: 558 Protein sequence Protein Accession ft: XP 057188.1
60
120
Figure imgf001168_0001
180
YSAFFLVDDG THGCLGGENR FRLRLESYIS QQKTGVGGTG IDIPVLLLLI DGDEKMLTRI 240
ENATQAQLPC LLVAGSGGAA DCLAETLEDT LAPGSGGARQ GEARDRIRRF FPKGDLEVLQ 300
AQVERIMTRK ELLTVYSSED GSEEFETIVL KALVKACGSS EASAYLDELR LAVAWNRVDI 360
AQSELFRGDI QWRSFHLEAS LMDALLNDRP EFVRLLISHG LSLGHFLTPM RLAQLYSAAP 420
SNSLIRNLLD QASHSAGTKA PALKGGAAEL RPPDVGHVLR MLLGKMCAPR YPSGGAWDPH 480
PGQ6FGESMY LLSDKATSPL SLDAGLGQAP WSDLLLWALL LNRAQMAMYF WEMGSNAVSS 540
ALGACLLLRV MARLEPDAEE AARRKDLAFK FEGMGVDLFG ECYRSSEVRA ARLLLRRCPL 600
WGDATCLQLA MQADARAFFA QDGVQSLLTQ KWWGDMASTT PIWALVLAFF CPPLIYTRLI 660
TFRKSEEEPT REELEFDMDS VINGEGPVGT ADPAEKTPLG VPRQSGRPGC CGGRCGGRRC 720 LRRWFHFWGA PVTIFMGNW SYLLFLLLFS RVLLVDFQPA PPGSLELLLY FWAFTLLCEE 780 LRQGLSGGGG SLASGGPGPG HASLSQRLRL YLADSWNQCD LVALTCFLLG VGCRLTPGLY 840 HLGRTVLCID FMVFTVRLLH IFTVNKQLGP KIVIVSKMMK DVFFFLFFLG VWLVAYGVAT 900 EGLLRPRDSD FPSILRRVFY RPYLQIFGQI PQEDMDVALM EHSNCSSEPG FWAHPPβAQA 960 GTCVSQYANW LWLLLVIFL LVANILLVNL LIAMFSYTFG KVQGNSDLYW KAQRYRLIRE 1020 FHSRPALAPP FIVISHLRLL LRQLCRRPRS PQPSSPALEH FRVYLSKEAE RKLLTWESVH 1080 KENFLLARAR DKRESDSERL KRTSQKVDLA LKQLGHIREY EQRLKVLERE VQQCSRVLGW 1140 VAEALSRSAL LPPGGPPPPD LPGSKD Seq ID NO: 559 DNA sequence
Nucleic Acid Accession ff: NM_006853.1 Coding sequence: 26..874
11 21 31 41 51
I I I I I
AGGAATCTGC GCTCCGGTTC CGCAGATGCA βAGGTTGAGG TGGCTGCGGG ACTGGAAβTC 60 ATCGGGCAGA GβTCTCACAG CAGCCAAGGA ACCTGGGGCC CGCTCCTCCC CCCTCCAGGC 120 CATGAGGATT CTGCAGTTAA TCCTGCTTGC TCTGGCAACA GGGCTTGTAG GβββAβAGAC 180 CAGβATCATC AAGGGGTTCG AGTGCAAGCC TCACTCCCAG CCCTGGCAGG CAGCCCTGTT 240 CβAβAAGACG CGGCTACTCT GTβββGCGAC GCTCATCGCC CCCAGATGGC TCCTGACAGC 300 AGCCCACTCC CTCAAGCCCC GCTACATAβT TCACCTGGβG CAGCACAACC TCCAGAAGGA 360 GGAGGGCT6T GAGCAGACCC GGACAGCCAC TGAβTCCTTC CCCCACCCCG GCTTCAACAA 420 CAGCCTCCCC AACAAAGACC ACCGCAATGA CATCATGCTG GTGAAGATGG CATCGCCAGT 480 CTCCATCACC TβββCTCTGC GACCCCTCAC CCTCTCCTCA CGCTGTGTCA CTGCTGGCAC 540 CAGCTGCCTC ATTTCCβGCT GGGGCAGCAC GTCCAGCCCC CAGTTACGCC TGCCTCACAC 600 CTTGCGATGC GCCAACATCA CCATCATTGA GCACCAGAAG TGTGAGAACG CCTACCCCGG 660 CAACATCACA GACACCATGβ TGTGTGCCAG CGTGCAGGAA GGGG6CAAGG ACTCCTGCCA 720 GGGTGACTCC GGGGGCCCTC TGβTCTβTAA CCAGTCTCTT CAAGβCATTA TCTCCTGGGG 780 CCAGGATCCG TGTGCGATCA CCCGAAAGCC TGGTGTCTAC ACGAAAGTCT GCAAATATGT 840 GGACTGGATC CAGGAGACGA TGAAGAACAA TTAGACTGGA CCCACCCACC ACAGCCCATC 900 ACCCTCCATT TCCACTTGGT GTTT6GTTCC TGTTCACTCT GTTAATAAGA AACCCTAAGC 960 CAAGACCCTC TACGAACATT CTTTGGGCCT CCTGGACTAC AGGAGATGCT GTCACTTAAT 1020 AATCAACCTG GGGTTCGAAA TCAGTGAGAC CTGGATTCAA ATTCTGCCTT GAAATATTGT 1080 GACTCTGGGA ATGACAACAC CTGGTTTGTT CTCTGTTGTA TCCCCAGCCC CAAAGACA6C 1140 TCCTGβCCAT ATATCAAGGT TTCAATAAAT ATTTGCTAAA TGAGTG
Seq ID NO: 560 Protein sequence Protein Accession ff: NP_006844.1
1 11 21 31 41 51
I I I I I I
MRILQLILLA LATGLVGGET RIIKGFECKP HSQPWQAALF EKTRLLC6AT LIAPRWLLTA 60
AHCLKPRYIV HLGQHNLQKE EGCEQTRTAT ESFPHPGFNN SLPNKDHRND IMLVKMASPV 120
SITWAVRPLT LSSRCVTAGT SCLISGWGST SSPQLRLPHT LRCANITIIE HQKCENAYPG 180
NITDTMVCAS VQEGβKDSCQ GDSGGPLVCN QSLQGIISWG QDPCAITRKP GVYTKVCKYV 240 DWIQETMKNN
Seq ID NO: 561 DNA εequence
Nucleic Acid Accession ft: AY046419.1
Coding sequence: 1..1743
1 11 21 31 41 51 1 1 | 1 | 1 1 | 1 | 1 ATGTTTACCT TCCTGTCATC TGTCACTGCT GCTGTCAGTG GCCTCCTGGT GGGTTATGAA 60
CTTGGGATCA TCTCTGGβGC TCTTCTTCAG ATCAAAACCT TATTAGCCCT GAGCTGCCAT 120
GAGCAGGAAA TGGTTβTGAG CTCCCTCGTC ATTGGAGCCC TCCTTGCCTC ACTCACCGGA 180
GGGGTCCTGA TAGACAGATA TGGAAGAAGG ACAGCAATCA TCTTGTCATC CTGCCTGCTT 240
GGACTCGGAA GCTTAGTCTT GATCCTCAGT TTATCCTACA CGGTTCTTAT AGTGGGACGC 300
ATTGCCATAG GGGTTTCCAT CTCCCTCTCT TCCATTGCCA CTTGTGTTTA CATCGCAGAG 360
ATTGCTCCTC AACACAGAAG AGβCCTTCTT GTGTCACTGA ATGAGCTGAT GATTGTCATC 420
GGCATTCTTT CTGCCTATAT TTCAAATTAC GCATTTGCCA ATGTTTTCCA TGGCTGGAAG 480
TACATGTTTG GTCTTGTGAT TCCCTTGGGA GTTTTGCAAG CAATTGCAAT GTATTTTCTT 540
CCTCCAAGCC CTCβGTTTCT GGTGATGAAA GGACAAGAGG GAGCTGCTAG CAAGGTTCTT 600
GGAAGβTTAA GAGCACTCTC AGATACAACT GAGGAACTCA CTGTGATCAA ATCCTCCCTG 660
AAAGATGAAT ATCAGTACAG TTTTTGGGAT CTGTTTCGTT CAAAAGACAA CATGCGGACC 720
CGAATAATGA TAGGACTAAC ACTAGTATTT TTTGTACAAA TCACTGGCCA ACCAAACATA 780
TTGTTCTATG CATCAACTGT TTTGAAGTCA GTTGGATTTC AAAGCAATGA GGCAGCTAGC 840
CTCGCCTCCA CTGGGGTTGG AGTCGTCAAG GTCATTAGCA CCATCCCTGC CACTCTTCTT 900
GTAGACCATG TCGGCAGCAA AACATTCCTC TGCATTGGCT CCTCTGTGAT GβCAβCTTCG 960
TTGGTGACCA TGGGCATCGT AAATCTCAAC ATCCACATGA ACTTCACCCA TATCTGCAGA 1020
AGCCACAATT CTATCAACCA GTCCTTGGAT GAGTCTGTGA TTTATGGACC AGGAAACCTG 1080
TCAACCAACA ACAATACTCT CAGAGACCAC TTCAAAGβGA TTTCTTCCCA TAGCAGAAGC 1140
TCACTCATGC CCCTGAGAAA TGATGTGGAT AAβAβAGGGG AGACGACCTC AGCATCCTTβ 1200
CTAAATGCTG GATTAAGCCA CACTGAATAC CAGATAGTCA CAGACCCTGG GβACGTCCCA 1260
GCTTTTTTGA AATGGCTGTC CTTAGCCA6C TTGCTTGTTT ATGTTGCTGC TTTTTCAATT 1320
GGTCTAGGAC CAATGCCCTG GCTGGTβCTC AGCGAGATCT TTCCTGGTGG GATCAGAGGA 1380
CGAβCCATGG CTTTAACTTC TAβCATβAAC TGGGGCATCA ATCTCCTCAT CTCGCTGACA 1440
TTTTTGACTG TAACTCATCT TATTGGCCTG CCATGGGTGT GCTTTATATA TACAATCATG 1500
AGTCTAGCAT CCCTGCTTTT TGTTGTTATG TTTATACCTG AβACAAAGGG ATGCTCTTTG 1560
GAACAAATAT CAATGGAGCT AGCAAAAGTG AACTATGTGA AAAACAACAT TT6TTTTATG 1620
AGTCATCACC AAGAAGAATT AGTGCCAAAA CAGCCTCAAA AAAGAAAACC CCAGGAGCAβ 1680
CTCTTGGAGT βTAACAAGCT GTGTGGTAGG GGCCAATCCA GGCAGCTTTC TCCAGAGACC 1740 TAA Seq ID NO: 562 Protein sequence Protein Accession ft: AAL02327.1
11 21 31 41 51
MFTFLSSVTA AVSGLLVGYE LGIISβALLQ IKTLLALSCH EQEMWSSLV IGALLASLTG 60 GVLIDRYGRR TAIILSSCLL GLGSLVLILS LSYTVLIVGR IAIGVSISLS SIATCVYIAE 120 IAPQHRRGLL VSLNELMIVI βlLSAYISNY AFANVFHGWK YMFGLVIPLG VLQAIAMYFL 180 PPSPRFLVMK GQEGAASKVL GRLRALSDTT EELTVIKSSL KDEYQYSFWD LFRSKDNMRT 240 RIMIGLTLVF FVQITGQPNI LFYASTVLKS VGFQSNEAAS LASTGVβ K VISTIPATLL 300 VDHVGSKTFL CIGSSVMAAS LVTMGIVNLN IHMNFTHICR SHNSINQSLD ESVIYGPGNL 360 STNNNTLRDH FKGISSHSRS SLMPLRNDVD KRGETTSASL LNAGLSHTEY QIVTDPGDVP 420 AFLKWLSLAS LLVYVAAFSI GLGPMPWLVL SEIFPGGIRG RAMALTSSMN WGINLLISLT 480 FLTVTDLIGL PWVCFIYTIM SLASLLFWM FIPETKGCSL EQISMELAKV NYVKNNICFM 540 SHHQEELVPK QPQKRKPQEQ LLECNKLCGR GQSRQLSPET
Seq ID NO: 563 DNA sequence
Nucleic Acid Accesεion #: XM_059466.1
Coding sequence: 1..894
11 21 31 41 51
I I I I I
ATGGAGCCGC GGGCGCTCGT CACβGCGCTC AGCCTCGGCC TCAGCCTGTG CTCCCTGGGG 60 CTGCTCGTCA CCβCCATCTT CACCGACCAC TGGTACGAGA CCGACCCCCG GCGCCACAAG 120 GAGAβCTβCG AGCGCAβCCG CGCGGGCGCC GACCCCCCGG ACCAβAAβAA CCGCCTGATG 180 CCGCTGTCβC ACCTGCCβCT GCGGGACTCG CCCCCGCTGG GGCGCCGGCT GCTCCCGGGC 240 GGCCCGGβGC GCGCCGACCC CGAGTCCTββ CGCTCGCTCC TGGGGCTCGG CGGGCTGGAC 300 GCCGAGTGCG GCCGGCCCCT CTTCβCCACC TACTCGGGCC TCTGGAGGAA GTβCTACTTC 360 CTGGGCATCG ACCGGGACAT CGACACCCTC ATCCTGAAAG GTATTGCGCA GCGATβCACG 420 GGCATCAAGT ACCACTTTTC TCAGCCCATC CGCTTGCGAA ACATTCCTTT TAATTTAACC 480 AAGACCATAC AGCAAGATGA GTGGCACCTG CTTCATTTAA GAAGAATCAC TGCTGGCTTC 540 CTCGβCATGG CCGTAGCCGT CCTTCTCTGC GGCTGCATTG TGβCCACAGT CAGTTTCTTC 600 TGGGAGGAGA GCTTGACCCA GCACGTGGCT GGACTCCTGT TCCTCATGAC AGGGATATTT 660 TGCACCATTT CCCTCTGTAC TTATGCCGCC AGTATCTCGT ATGATTTGAA cceecTcccA 720 AAGCTAATTT ATAGCCTCCC TGCTβATGTG GAACATGβTT ACAGCTGGTC CATCTTTTGC 780 GCCTGGTGCA GTTTAGGCTT TATTGTGGCA GCTGGAGGTC TCTGCATCGC TTATCCGTTT 840 ATTAGCCGGA CCAAGATTGC ACAGCTAAAG TCTGGCAGAG ACTCCACGGT ATGA
Seq ID NO: 564 Protein sequence Protein Accession ft: XP 059466.1
11 21 31 41 51
I I I I I
MEPRALVTAL SLGLSLCSLG LLVTAIFTDH WYETDPRRHK ESCERSRAGA DPPDQKNRLM 60 PLSHLPLRDS PPLGRRLLPG GPGRADPESW RSLLGLGGLD AECGRPLFAT YSGLWRKCYF 120 LGIDRDIDTL ILKGIAQRCT AIKYHFSQPI RLRNIPFNLT KTIQQDEWHL LHLRRITAGF 180 LGMAVAVLLC GCIVATVSFF WEESLTQHVA GLLFLMTGIF CTISLCTYAA SISYDLNRLP 240 KLIYSLPADV EHGYSWSIFC AWCSLGFIVA AGGLCIAYPF ISRTKIAQLK SGRDSTV
Seq ID NO: 565 DNA sequence
Nucleic Acid Accesεion #: Eos sequence
Coding sequence: 1..3315
11 21 31
ATGTCCTTTC GGGCAGCCAG GCTCAGCATG AGGAACAGAA GGAATGACAC TCTGGACAGC 60
ACCCGGACCC TGTACTCCAG CGCGTCTCGG AGCACAGACT TGTCTTACAG TGAAAGCGAC 120
TTGGTGAATT TTATTCAAGC AAATTTTAAG AAACGAGAAT GTGTCTTCTT TACCAAAGAT 180
TCCAAGGCCA CGGAGAATGT GTGCAAGTβT GGCTATGCCC AGAβCCAGCA CATGGAAGGC 240
ACCCAGATCA ACCAAAGTGA GAAATGGAAC TACAAGAAAC ACACCAAGGA ATTTCCTACC 300
GACGCCTTTG GGGATATTCA GTTTGAGACA CTGGGGAAGA AAGGGAAGTA TATACGTCTG 360
TCCTGC6ACA CGGACGCGGA AATCCTTTAC GAGCTGCTGA CCCAGCACTG GCACCTGAAA 420
ACACCCAACC TGGTCATTTC TGTGACCGGG GGCGCCAAGA ACTTCGCCCT GAAGCCGCGC 480
ATGCGCAAGA TCTTCAGCCG GCTCATCTAC ATCGCGCAGT CCAAAGGTGC TTGGATTCTC 540
ACGGGAGGCA CCCATTATGG CCTGATGAAG TACATCGGGG AGGTβGTGAG AGATAACACC 600
ATCAGCAGGA GTTCAGAβGA GAATATTGTG GCCATTGGCA TAGCAGCTTG GGGCATGGTC 660
TCCAACCGGG ACACCCTCAT CAGGAATTGC GATGCTGAGG GCTATTTTTT AGCCCAGTAC 720
CTTATGβATβ ACTTCACAAG AGATCCACTG TATATCCTGG ACAACAACCA CACACATTTG 780
CTGCTCGTGG ACAATGGCTG TCATGβACAT CCCACTGTCG AAGCAAAGCT CCGβAATCAG 840
CTAGAGAAGT ATATCTCTGA GCGCACTATT CAAGATTCCA ACTATGGTGG CAAGATCCCC 900
ATTGTGTGTT TTGCCCAAGG AGGTGGAAAA GAGACTTTGA AAGCCATCAA TACCTCCATC 960
AAAAATAAAA TTCCTTGTGT GGTGGTGβAA GGCTCGGGCC AGATCGCTGA TGTGATCGCT 1020
AGCCTGGTGG AGGTGGAGGA TGCCCTGACA TCTTCTGCCG TCAAGGAGAA GCTGGTGCGC 1080
TTTTTACCCC GCACGGTGTC CCGGCTGCCT GAGGAGGAGA CTGAGAGTTG GATCAAATGG 1140
CTCAAAGAAA TTCTCGAATG TTCTCACCTA TTAACAGTTA TTAAAATGGA AGAAGCTGGG 1200
GATGAAATTG TGAGCAATGC CATCTCCTAC GCTCTATACA AAGCCTTCAG CACCAGTGAG 1260
CAAGACAAGG ATAACTGGAA TGGGCAGCTG AAGCTTCTGC TGGAGTGGAA CCAGCTGGAC 1320
TTAGCCAATG ATGAGATTTT CACCAATGAC CGCCGATGGG AGTCTGCTGA CCTTCAAGAA 1380
GTCATGTTTA CGGCTCTCAT AAAGGACAGA CCCAAGTTTG TCCGCCTCTT TCTGGAGAAT 1440 βGCTTGAACC TACGGAAGTT TCTCACCCAT GATGTCCTCA CTβAACTCTT CTCCAACCAC 1500
TTCAGCACGC TTGTβTACCG GAATCTGCAG ATCGCCAAGA ATTCCTATAA TGATGCCCTC 1560
CTCACGTTTG TCTGGAAACT GGTTGCGAAC TTCCGAAGAG GCTTCCGGAA GGAAGACAGA 1620
AATGGCCGGG ACGAβATββA CATAGAACTC CACGACGTGT CTCCTATTAC TCGGCACCCC 1680
CTGCAAGCTC TCTTCATCTG GGCCATTCTT CAGAATAAGA AGGAACTCTC CAAAGTCATT 1740 TGGGAGCAGA CCAGGGGCTG CACTCTGGCA βCCCTGGGAG CCAGCAAGCT TCTGAAGACT 1800 CTGGCCAAAG TGAAGAACGA CATCAATGCT GCTGGGGAGT CCGAGGAGCT GGCTAATGAG 1860 TACGAGACCC GGGCTGTTGA GCTGTTCACT GAβTGTTACA GCAGCGATGA AGACTTGGCA 1920 GAACAGCTGC TGGTCTATTC CTGTGAAGCT TGGGGTGGAA GCAACTGTCT GGAGCTGGCG 1980 GTGGAGGCCA CAGACCAGCA TTTCATCGCC CAGCCTGGGG TCCAGAATTT TCTTTCTAAG 2040 CAATGGTATG GAGAGATTTC CCGAGACACC AAGAACTGGA AGATTATCCT GTGTCTGTTT 2100 ATTATACCCT TGGTGGβCTβ TGGCTTTGTA TCATTTAGGA AGAAACCTGT CGACAAGCAC 2160 AAGAAGCTGC TTTGGTACTA TGTGGCGTTC TTCACCTCCC CCTTCGTGGT CTTCTCCTGG 2220 AATGTGGTCT TCTACATCGC CTTCCTCCTG CTGTTTGCCT ACGTGCTGCT CATGGATTTC 2280 CATTCGGTβC CACACCCCCC CGAGCTGGTC CTGTACTCGC TGGTCTTTGT CCTCTTCTGT 2340 GATGAAGTGA GACAGTGGTA CGTAAATGGG GTGAATTATT TTACTGACCT βTGGAATβTβ 2400 ATGGACACGC TGGGGCTTTT TTACTTCATA GCAGβAATTG TATTTCGGCT CCACTCTTCT 2460 AATAAAAGCT CTTTGTATTC TGGACGAGTC ATTTTCTGTC TGGACTACAT TATTTTCACT 2520 CTAAGATTGA TCCACATTTT TACTGTAAGC AGAAACTTAG GACCCAAGAT TATAATGCTG 2580 CAGAGGATGC TGATCGATGT GTTCTTCTTC CTGTTCCTCT TTGCGGTGTG GATGGTGGCC 2640 TTTGGCGTββ CCAββCAAββ GATCCTTAGG CAGAATGAGC AGCGCTGβAG GTGGATATTC 2700 CGTTCGGTCA TCTACGAGCC CTACCTGGCC ATGTTCGGCC AGGTGCCCAG TGACGTβGAT 2760 GGTACCACβT ATGACTTTGC CCACTGCACC TTCACTGGGA ATGAGTCCAA GCCACTGTGT 2820 GTGGAGCTGβ ATGAGCACAA CCTGCCCCGG TTCCCCGAGT GGATCACCAT CCCCCTGGTG 2880 TGCATCTACA TGTTATCCAC CAACATCCTG CTGGTCAACC TGCTGGTCGC CATGTTTGGC 2940 TACACGGTGG GCACCGTCCA GGAGAACAAT GACCAGGTCT GGAAGTTCCA GAGGTACTTC 3000 CTGGTGCAGG AGTACTGCAG CCGCCTCAAT ATCCCCTTCC CCTTCATCGT CTTCGCTTAC 3060 TTCTACATGβ TGGTGAAβAA GTGCTTCAAG TβTTGCTGCA AGGAGAAAAA CATGGAGTCT 3120 TCTCTCTGCT GTTTCAAAAA TGAAGACAAT GAGACTCTGG CATGGGAGGG TGTCATGAAG 3180 GAAAACTACC TTGTCAAGAT CAACACAAAA βCCAACGACA CCTCAGAGGA AATGAGGCAT 3240 CGATTTAGAC AACTGGATAC AAAGCTTAAT GATCTCAAGβ GTCTTCTGAA AGAGATTGCT 3300 AATAAAATCA AATGA
Seq ID NO: 566 Protein sequence Protein Accession #: Eos sequence
11 21 31 41 51
I I I I I
MSFRAARLSM RNRRNDTLDS TRTLYSSASR STDLSYSESD LVNFIQANFK KRECVFFTKD 60 SKATENVCKC GYAQSQHMEG TQINQSEKWN YKKHTKEFPT DAFGDIQFET LGKKGKYIRL 120 SCDTDAEILY ELLTQHWHLK TPNLVISVTG GAKNFALKPR MRKIFSRLIY IAQSKβAWIL 180 TGGTHYGLMK YIGEWRDNT ISRSSEENIV AIGIAAWGMV SNRDTLIRNC DAEGYFLAQY 240 LMDDFTRDPL YILDNNHTHL LLVDNGCHGH PTVEAKLRNQ LEKYISERTI QDSNYGGKIP 300 IVCFAQGGGK ETLKAINTSI KNKIPCWE GSGQIADVIA SLVEVEDALT SSAVKEKLVR 360 FLPRTVSRLP EEETESWIKW LKEILECSHL LTVIKMEEAG DEIVSNAISY ALYKAFSTSE 420 QDKDNWNGQL KLLLEWNQLD LANDEIFTND RRWESADLQE VMFTALIKDR PKFVRLFLEN 480 GLNLRKFLTH DVLTELFSNH FSTLVYRNLQ IAKNSYNDAL LTFVWKLVAN FRRβFRKEDR 540 NGRDEMDIEL HDVSPITRHP LQALFIWAIL QNKKELSKVI WEQTRGCTLA ALGASKLLKT 600 LAKVKNDINA AGESEELANE YETRAVELFT ECYSSDEDLA EQLLVYSCEA WGGSNCLELA 660 VEATDQHFIA QPGVQNFLSK QWYGEISRDT KNWKIILCLF IIPLVGCGFV SFRKKPVDKH 720 KKLLWYYVAF FTSPFWFSW NWFYIAFLL LFAYVLLMDF HSVPHPPELV LYSLVFVLFC 780 DEVRQWYVNG VNYFTDLWNV MDTLGLFYFI AGIVFRLHSS NKSSLYSGRV IFCLDYIIFT 840 LRLIHIFTVS RNLGPKIIML QRMLIDVFFF LFLFAVWMVA FGVARQGILR QNEQRWRWIF 900 RSVIYEPYLA MFGQVPSDVD GTTYDFAHCT FTGNESKPLC VELDEHNLPR FPEWITIPLV 960 CIYMLSTNIL LVNLLVAMFG YTVGTVQENN DQVWKFQRYF LVQEYCSRLN IPFPFIVFAY 1020 FYMWKKCFK CCCKEKNMES SVCCFKNEDN ETLAWEGVMK ENYLVKINTK ANDTSEEMRH 1080 RFRQLDTKLN DLKGLLKEIA NKIK
Seq ID NO: 567 DNA sequence Nucleic Acid Accesεion ft: NM_006911.1 Coding εequence: 1..558
11 21 31 41 51
I I I I I
ATGCCTCGCC TGTTCTTGTT CCACCTGCTA GAATTCTGTT TACTACTGAA CCAATTTTCC 60 AGAGCAGTCG CGGCCAAATG GAAGGACGAT GTTATTAAAT TATGCGGCCG CGAATTAGTT 120 CGCGCGCAGA TTGCCATTTG CGGCATGAGC ACCTGGAβCA AAAGGTCTCT GAGCCAGGAA 180 GATGCTCCTC AGACACCTAG ACCAGTGGCA GAAATTGTAC CATCCTTCAT CAACAAAGAT 240 ACAGAAACTA TAATTATCAT GTTGGAATTC ATTGCTAATT TGCCACCGGA GCTGAAGGCA 300 GCCCTATCTG AGAGGCAACC ATCATTACCA GAGCTACAGC AGTATGTACC TGCATTAAAG 360 GATTCCAATC TTAGCTTTGA AGAATTTAAG AAACTTATTC GCAATAGGCA AAGTGAAGCC 420 GCAGACAGCA ATCCTTCAGA ATTAAAATAC TTAGGCTTGG ATACTCATTC TCAAAAAAAG 480 AGACGACCCT ACGTGGCACT GTTTGAGAAA TGTTGCCTAA TTGGTTGTAC CAAAAGGTCT 540 CTTGCTAAAT ATTGCTGA
Seq ID NO: 568 Protein εequence Protein Accession ft: NP_008842.1
1 11 21 31 41 51
I I I I . I I
MPRLFLFHLL EFCLLLNQFS RAVAAKWKDD VIKLCGRELV RAQIAICGMS TWSKRSLSQE 60 DAPQTPRPVA EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK 120 DSNLSFEEFK KLIRNRQSEA ADSNPSELKY LGLDTHSQKK RRPYVALFEK CCLIGCTKRS 180 LAKYC
Seq ID NO: 569 DNA sequence
Nucleic Acid Accession ft: XM 036453.1 Coding sequence: 1..3978
1 11 21 31 41 51
I I I I I I
ATGCTGCCCG TGTACCAGGA GGTGAAGCCC AACCCGCTGC AGGACGCGAA CCTCTGCTCA 60
CGCGTGTTCT TCTGGTGβCT CAATCCCTTβ TTTAAAATTG GCCATAAACG GAGATTAGAG 120 βAAGATGATA TGTATTCAGT GCTGCCAGAA GACCGCTCAC AGCACCTTGG AGAGGAGTTG 180
CAAGGGTTCT GGGATAAAGA AGTTTTAAGA GCTGAGAATG ACβCACAGAA GCCTTCTTTA 240
ACAAGAGCAA TCATAAAGTG TTACTGGAAA TCTTATTTAG TTTTGGGAAT TTTTAC6TTA 300
ATTGAGGAAA GTGCCAAAGT AATCCAGCCC ATATTTTTβG GAAAAATTAT TAATTATTTT 360
GAAAATTATG ATCCCATββA TTCTGTGGCT TTGAACACAG CGTACGCCTA TGCCACCGTG 420
CTGACTTTTT GCACGCTCAT TTTGβCTATA CTβCATCACT TATATTTTTA TCACGTTCAG 480
TGTGCTGG6A TGAGGTTACG AGTAGCCATβ TβCCATATGA TTTATCGGAA GGCACTTCGT 540
CTTAGTAACA TGGCCATGGG GAAGACAACC ACAGGCCAGA TAGTCAATCT GCTGTCCAAT 600
GATGTGAACA AGTTTGATCA GGTGACAGTβ TTCTTACACT TCCTGTGGGC AGGACCACTG 660
CAGGCGATCG CAGTGACTGC CCTACTCTGG ATGβAGATAG 6AATATCGTG CCTTGCTGGG 720
ATGGCAGTTC TAATCATTCT CCTGCCCTTG CAAAGCTGTT TTGGGAAGTT GTTCTCATCA 780
CTGAGGAGTA AAACTGCAAC TTTCACGGAT GCCAGGATCA GGACCATCAA TGAAGTTATA 840
ACTGGTATAA GGATAATAAA AATGTACGCC TGβGAAAAGT CATTTTCAAA TCTTATTACC 900
AATTTGAGAA AGAAGGAGAT TTCCAAGATT CTGAGAAGTT CCTGCCTCAG GG6GATGAAT 960
TTGGCTTCGT TTTTCAGTGC AAGCAAAATC ATCGTGTTTG TGACCTTCAC CACCTACGTG 1020
CTCCTCGGCA GTGTGATCAC AGCCAGCCGC GTβTTCβTGG CAGTGACGCT GTATGGGGCT 1080 βTGCGGCTGA CGGTTACCCT CTTCTTCCCC TCAGCCATTG AGAGGGTGTC AGAGGCAATC 1140
GTCAGCATCC GAAGAATCCA GACCTTTTTG CTACTTGATG AGATATCACA GCGCAACCGT 1200
CAGCTGCCGT CAGATGGTAA AAAGATGGTβ CATGTGCAGG ATTTTACTGC TTTTTGGGAT 1260
AAGGCATCAG AGACCCCAAC TCTACAAGGC CTTTCCTTTA CTGTCAGACC TGβCCAATTG 1320
TTAGCTGTGG TCGGCCCCGT GGGAGCAGGG AAβTCATCAC TGTTAAGTGC CGTGCTCGGG 1380
GAATTGGCCC CAAGTCACGG GCTGGTCAGC GTGCATGGAA GAATTGCCTA TGTGTCTCAG 1440
CAGCCCTGGβ TGTTCTCGGG AACTCTGAGG AGTAATATTT TATTTGGβAA GAAATACGAA 1500
AAGGAACGAT ATGAAAAAGT CATAAAGGCT TGTGCTCTGA AAAAGGATTT ACAGCTGTTG 1560
GAβGATGGTG ATCTGACTGT GATAGβAβAT CGGGGAACCA CGCTGAGTGG AGGGCAGAAA 1620
GCACGGGTAA ACCTTGCAAG AGCAGT6TAT CAAGATGCTG ACATCTATCT CCTGGACGAT 1680
CCTCTCAGTG CAGTAGATGC GGAAGTTAGC AGACACTTGT TCGAACTGTβ TATTTGTCAA 1740
ATTTTGCATG AGAAGATCAC AATTTTAGTG ACTCATCAGT TβCAβTACCT CAAAGCTGCA 1800
AGTCAGATTC TGATATTGAA AGATGGTAAA ATGGTGCAβA AβGGGACTTA CACTGAGTTC 1860
CTAAAATCTG GTATAGATTT TGGCTCCCTT TTAAAGAAGG ATAATβAββA AAGTGAACAA 1920
CCTCCAGTTC CAGGAACTCC CACACTAAGG AATCGTACCT TCTCAGAGTC TTCGGTTTGG 1980
TCTCAACAAT CTTCTAGACC CTCCTTGAAA GATGGTGCTC TGGAGAGCCA AGATACAGAG 2040
AATGTCCCAG TTACACTATC AGAGβAGAAC CGTTCTGAAG GAAAAGTTGG TTTTCAGGCC 2100
TATAAGAATT ACTTCAGAGC TGβTβCTCAC TGGATTGTCT TCATTTTCCT TATTCTCCTA 2160
AACACTGCAG CTCAGGTTGC CTATGTGCTT CAAGATTGGT GGCTTTCATA CTGGGCAAAC 2220
AAACAAAGTA TGCTAAATGT CACTGTAAAT GGAGGAGGAA ATGTAACCβA GAAGCTAGAT 2280
CTTAACTGGT ACTTAGGAAT TTATTCAGGT TTAACTGTAG CTACCGTTCT TTTTGGCATA 2340
GCAAGATCTC TATTGGTATT CTACGTCCTT GTTAACTCTT CACAAACTTT GCACAACAAA 2400
ATGTTTGAGT CAATTCTGAA AGCTCCGGTA TTATTCTTTG ATAGAAATCC AATAGβAAβA 2460
ATTTTAAATC GTTTCTCCAA AGACATTGGA CACTTGGATG ATTTGCTGCC GCTGACGTTT 2520
TTAGATTTCA TCCAGACATT GCTACAAGTG GTTGGTGTGG TCTCTGTGGC TGTGGCCGTG 2580
ATTCCTTGGA TCGCAATACC CTTGGTTCCC CTTGGAATCA TTTTCATTTT TCTTCGGCGA 2640
TATTTTTTGG AAACGTCAAG AGATβTGAAG CGCCTβGAAT CTACAACTCG GAGTCCAGTG 2700
TTTTCCCACT TGTCATCTTC TCTCCAGGGG CTCTGGACCA TCCGGGCATA CAAAGCAGAA 2760
GAGAGGTβTC AGGAACTGTT TGATGCACAC CAGGATTTAC ATTCAGAGGC TTGGTTCTTG 2820
TTTTTGACAA CGTCCCGCTG GTTCGCCGTC CGTCTGGATG CCATCTGTGC CATGTTTGTC 2880
ATCATCGTTG CCTTTGββTC CCTGATTCTG GCAAAAACTC TGGATGCCGG GCAGGTTGGT 2940
TTGGCACTGT CCTATGCCCT CACGCTCATG GGGATGTTTC AGTGGTβTGT TCGACAAAGT 3000
GCTGAAGTTG AGAATATGAT GATCTCAGTA GAAAGGGTCA TTGAATACAC AGACCTTGAA 3060
AAAGAAGCAC CTTGGGAATA TCAGAAACGC CCACCACCAG CCTGGCCCCA TGAAGGAGTG 3120
ATAATCTTTG ACAATGTGAA CTTCATGTAC AGTCCAGGTG GGCCTCTGGT ACTGAAGCAT 3180
CTGACAGCAC TCATTAAATC ACAAGAAAAG GTTGGCATTG TGGGAAGAAC CGGAGCTGGA 3240
AAAAGTTCCC TCATCTCAGC CCTTTTTAGA TTGTCAGAAC CCGAAGGTAA AATTTGGATT 3300
GATAAGATCT TGACAACTGA AATTGGACTT CACGATTTAA GGAAGAAAAT GTCAATCATA 3360
CCTCAGGAAC CTGTTTTGTT CACTGGAACA ATGAββAAAA ACCTβGATCC CTTTAATGAG 3420
CACACGGATG AGGAACTGTG GAATGCCTTA CAAGAGGTAC AACTTAAAGA AACCATTGAA 3480
GATCTTCCTG GTAAAATGGA TACTGAATTA GCAGAATCAG GATCCAATTT TAGTGTTGGA 3540
CAAAGACAAC TGGTGTGCCT TGCCAGGGCA ATTCTCAGGA AAAATCAGAT ATTGATTATT 3600
GATGAAGCGA CGGCAAATGT GGATCCAAGA ACTGATGAGT TAATACAAAA AAAAATCCGG 3660
GAGAAATTTG CCCACTGCAC CGTGCTAACC ATTGCACACA GATTGAACAC CATTATTGAC 3720
AGCGACAAGA TAATGGTTTT AGATTCAGGA AGACTGAAAG AATATGATGA βCCGTATGTT 3780
TTGCTGCAAA ATAAAGAGAG CCTATTTTAC AAGATGGTGC AACAACTGGG CAAGGCAGAA 3840
GCCGCTGCCC TCACTGAAAC AGCAAAACAG GTATACTTCA AAAGAAATTA TCCACATATT 3900
GGTCACACTβ ACCACATGGT TACAAACACT TCCAATGGAC AGCCCTCGAC CTTAACTATT 3960 TTCGAGACAG CACTGTGA
Seq ID NO: 570 Protein sequence Protein Accesεion ft: XP 036453.1
11 21 31 41 51
I I I I
MLPVYQEVKP NPLQDANLCS RVFFWWLNPL FKIGHKRRLE E IDDMYSVLPE DRSQHLβEEL 60 QGFWDKEVLR AENDAQKPSL TRAIIKCYWK SYLVLGIFTL IEESAKVIQP IFLGKIINYF 120 ENYDPMDSVA LNTAYAYATV LTFCTLILAI LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR 180 LSNMAMGKTT TGQIVNLLSN DVNKFDQVTV FLHFLWAGPL QAIAVTALLW MEIGISCLAG 240 MAVLIILLPL QSCFGKLFSS LRSKTATFTD ARIRTMNEVI TGIRIIKMYA WEKSFSNLIT 300 NLRKKEISKI LRSSCLRGMN LASFFSAΞKI IVFVTFTTYV LLGSVITASR VFVAVTLYGA 360 VRLTVTLFFP SAIERVSEAI VSIRRIQTFL LLDEISQRNR QLPSDGKKMV HVQDFTAFWD 420 KASETPTLQG LSFTVRPGEL LAWGPVGAG KSSLLSAVLG ELAPSHGLVS VHGRIAYVSQ 480 QPWVFSGTLR SNILFGKKYE KERYEKVIKA CALKKDLQLL EDβDLTVIβD RGTTLSGGQK 540 ARVNLARAVY QDADIYLLDD PLSAVDAEVS RHLFELCICQ ILHEKITILV THQLQYLKAA 600 SQILILKDGK MVQKGTYTEF LKSGIDFGSL LKKDNEESEQ PPVPGTPTLR NRTFSESSVW 660 SQQSSRPSLK DGALESQDTE NVPVTLSEEN RSEGKVGFQA YKNYFRAGAH WIVFIFLILL 720 NTAAQVAYVL QDWWLSYWAN KQSMLNVTVN GGGNVTEKLD LNWYLGIYSG LTVATVLFGI 780 ARSLLVFYVL VNSSQTLHNK MFESILKAPV LFFDRNPIGR ILNRFSKDIG HLDDLLPLTF 840 LDFIQTLLQV VGWSVAVAV IPWIAIPLVP LβUFIFLRR YFLETSRDVK RLESTTRSPV 900 FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV RLDAICAMFV 960 IIVAFGSLIL AKTLDAGQVG LALSYALTLM βMFQWCVRQS AEVENMMISV ERVIEYTDLE 1020 KEAPWEYQKR PPPAWPHEGV IIFDNVNFMY SPGGPLVLKH LTALIKSQEK VβlVβRTGAG 1080 KSSLISALFR LSEPEGKIWI DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFNE 1140 HTDEELWNAL QEVQLKETIE DLPGKMDTEL AESGSNFSVβ QRQLVCLARA ILRKNQILII 1200 DEATANVDPR TDELIQKKIR EKFAHCTVLT lAHRLNTIID SDKIMVLDSG RLKEYDEPYV 1260 LLQNKESLFY KMVQQLGKAE AAALTETAKQ VYFKRNYPHI GHTDHMVTNT SNGQPSTLTI 1320 FETAL
Seq ID NO. 571 DNA εequence Nucleic Acid Acceεεion ft AF07120 Coding εequence 116 4093
1 11 21 31 41 51
G IGACAGGCGT GIβCGGCCGGA GIGCCCAGCAT CICCTGCTTGA GIGTCCAGGAG CIGGAGCCCGC 60
GGCCACCGCC GCCTGATCAG CGC6ACCCCG GCCCGCβCCC GCCCCGCCCG GCAAGATGCT 120
GCCCGTGTAC CAGGAGGTGA AGCCCAACCC GCTGCAGGAC GCGAACATCT GCTCACGCGT 180
GTTCTTCTGG TGGCTCAATC CCTTGTTTAA AATTGGCCAT AAACGGAGAT TAGAGGAAGA 240
TGATATGTAT TCAGTGCTGC CAGAAGACCG CTCACAGCAC CTTGGAGAGβ AGTTGCAAGβ 300
GTTCTGGGAT AAAGAAGTTT TAAGAGCTGA GAATGACGCA CAGAAGCCTT CTTTAACAAG 360
AGCAATCATA AAGTGTTACT GGAAATCTTA TTTAGTTTTG GGAATTTTTA CGTTAATTGA 420
GGAAAGTGCC AAAGTAATCC AGCCCATATT TTTβββAAAA ATTATTAATT ATTTTGAAAA 480
TTATGATCCC ATGGATTCTG TGGCTTTGAA CACAGCGTAC GCCTATGCCA CGGTGCTGAC 540
TTTTTGCACG CTCATTTTGG CTATACTGCA TCACTTATAT TTTTATCACG TTCAGTGTGC 600
TGGGATGAGG TTACGAGTAG CCATGTβCCA TATGATTTAT CGGAAGGCAC TTCGTCTTAG 660
TAACATGGCC ATGGGGAAGA CAACCACAGG CCAGATAGTC AATCTGCTβT CCAATβATβT 720
GAACAAGTTT GATCAGGTGA CAGTGTTCTT ACACTTCCTG TGGGCAGGAC CACTGCAGGC 780
GATCGCAGTβ ACTGCCCTAC TCTGGATβGA GATAGGAATA TCGTGCCTTG CTGGGATGβC 840
AGTTCTAATC ATTCTCCTGC CCTTGCAAAG CTGTTTTGGG AAGTTGTTCT CATCACTGAG 900
GAGTAAAACT GCAACTTTCA CGGATβCCAG GATCAGGACC ATGAATGAAG TTATAACTGG 960
TATAAGGATA ATAAAAATGT ACGCCTβGGA AAAGTCATTT TCAAATCTTA TTACCAATTT 1020
GAGAAAGAAG βAGATTTCCA AGATTCTGAG AAGTTCCTGC CTCAGGGGGA TGAATTTGGC 1080
TTCGTTTTTC AGTGCAAGCA AAATCATCGT GTTTGTGACC TTCACCACCT ACGTGCTCCT 1140
CGGCACTGTG ATCACAGCCA GCCGCGTGTT CGTGGCAGTG ACGCTGTATG GGGCTGTGCG 1200
GCTGACGGTT ACCCTCTTCT TCCCCTCAGC CATTGAGAGG βTGTCAGAGG CAATCGTCAG 1260
CATCCGAAGA ATCCAGACCT TTTTGCTACT TGATGAGATA TCACAGCGCA ACCGTCAGCT 1320
GCCGTCAGAT βGTAAAAAGA TGGTGCATGT GCAGGATTTT ACTGCTTTTT GGGATAA6GC 1380
ATCAGAβACC CCAACTCTAC AAGGCCTTTC CTTTACTβTC AGACCTGGCG AATTGTTAGC 1440
TGTGGTCGGC CCCGTGGGAG CAGGGAAGTC ATCACTGTTA AGTGCCGTGC TCGGGGAATT 1500
GGCCCCAAGT CACGGGCTGG TCAGCβTGCA TGGAAGAATT GCCTATGTGT CTCAGCAβCC 1560
CTGGGTGTTC TCGGGAACTC TGAGGAGTAA TATTTTATTT GGβAAβAAAT ATGAAAAGGA 1620
ACGATATGAA AAAGTCATAA AGGCTTGTGC TCTGAAAAAG GATTTACAGC TGTTGGAGGA 1680
TGGTGATCTG ACTGTGATAG GAGATCGGGG AACCACGCTG AGTGGAGGGC AGAAAGCACG 1740
GGTAAACCTT GCAAGAGCAG TGTATCAAGA TGCTGACATC TATCTCCTGG ACGATCCTCT 1800
CAGTGCAGTA GATGCGGAAG TTAGCAβACA CTTβTTCGAA CTGTGTATTT GTCAAATTTT 1860
GCATGAGAAG ATCACAATTT TAGTGACTCA TCAGTTGCAG TACCTCAAAG CTGCAAGTCA 1920
GATTCTGATA TTβAAAGATG GTAAAATGGT GCAGAAGGGG ACTTACACTG AGTTCCTAAA 1980
ATCTGβTATA GATTTTGGCT CCCTTTTAAA GAAGGATAAT GAGGAAAGTG AACAACCTCC 2040
AGTTCCAGGA ACTCCCACAC TAAGGAATCG TACCTTCTCA GAGTCTTCGG TTTGGTCTCA 2100
ACAATCTTCT AGACCCTCCT TGAAAGATGG TGCTCTGGAG AGCCAAGATA CAGAGAATGT 2160
CCCAGTTACA CTATCAGAGG AGAACCGTTC TGAAGGAAAA GTTGGTTTTC AGGCCTATAA 2220
GAATTACTTC AGAGCTGGTG CTCACTGGAT TGTCTTCATT TTCCTTATTC TCCTAAACAC 2280
TGCAGCTCAG GTTGCCTATG TGCTTCAAGA TTGGTGGCTT TCATACTGGG CAAACAAACA 2340
AAGTATGCTA AATGTCACTG TAAATGGAGG AGGAAATGTA ACCGAGAAGC TAGATCTTAA 2400
CTGGTACTTA GGAATTTATT CAGGTTTAAC TGTAβCTACC GTTCTTTTTG βCATAβCAAG 2460
ATCTCTATTG GTATTCTACG TCCTTGTTAA CTCTTCACAA ACTTTGCACA ACAAAATGTT 2520
TGAGTCAATT CTGAAAGCTC CGβTATTATT CTTTGATAGA AATCCAATAG βAAGAATTTT 2580
AAATCGTTTC TCCAAAGACA TTGGACACTT GGATGATTTG CTGCCGCTGA CGTTTTTAGA 2640
TTTCATCCAG ACATTβCTAC AAGTGGTTGG TGTGGTCTCT GTGGCTGTGG CCGTGATTCC 2700
TTGGATCGCA ATACCCTTGG TTCCCCTTGG AATCATTTTC ATTTTTCTTC GGCGATATTT 2760
TTTGGAAACG TCAAGAGATG TGAAGCGCCT GGAATCTACA ACTCGGAGTC CAGTGTTTTC 2820
CCACTTGTCA TCTTCTCTCC AGGGGCTCTG GACCATCCGG GCATACAAAG CAGAAGAGAG 2880
GTGTCAGGAA CTGTTTGATG CACACCAGGA TTTACATTCA GAGβCTTGβT TCTTGTTTTT 2940
GACAACGTCC CGCTGGTTCG CCGTCCGTCT GGATGCCATC TGTGCCATGT TTGTCATCAT 3000
CGTTGCCTTT GGGTCCCTGA TTCTGGCAAA AACTCTGGAT GCCGGGCAGG TTGGTTTGGC 3060
ACTGTCCTAT GCCCTCACeC TCATGGGGAT GTTTCAGTGG TGTGTTCGAC AAAGTGCTGA 3120
AGTTGAGAAT ATGATGATCT CAGTAGAAAG GGTCATTGAA TACACAGACC TTGAAAAAGA 3180
AGCACCTTGG GAATATCAGA AACGCCCACC ACCAGCCTGG CCCCATGAAG GAGTGATAAT 3240
CTTTGACAAT GTGAACTTCA TGTACAGTCC AGGTGGGCCT CTGGTACTGA AGCATCTGAC 3300
AGCACTCATT AAATCACAAG AAAAGGTTGG CATTGTGGGA AGAACCGGAβ CTGGAAAAAG 3360
TTCCCTCATC TCAGCCCTTT TTAGATTGTC AGAACCCGAA GGTAAAATTT GGATTGATAA 3420
GATCTTGACA ACTGAAATTG GACTTCACGA TTTAAGGAAG AAAATGTCAA TCATACCTCA 3480
GGAACCTGTT TTGTTCACTG GAACAAT6AG GAAAAACCTG GATCCCTTTA AGGAGCACAC 3540
GGATGAGGAA CTGTGGAATG CCTTACAAGA GGTACAACTT AAAGAAACCA TTGAAGATCT 3600 TCCTGGTAAA ATGGATACTG AATTAGCAGA ATCAGGATCC AATTTTAGTG TTGGACAAAG 3660 ACAACTGGTG TGCCTTβCCA GGβCAATTCT CAGGAAAAAT CAGATATTGA TTATTGATGA 3720 AGCGACGGCA AATGTGGATC CAAβAACTGA TGAGTTAATA CAAAAAAAAA TCCGGGAGAA 3780 ATTTGCCCAC TGCACCGTGC TAACCATTGC ACACAGATTG AACACCATTA TTGACAGCGA 3840 CAAGATAATG GTTTTAGATT CAGGAAGACT GAAAGAATAT GATGAGCCGT ATGTTTTGCT 3900 GCAAAATAAA GAGAGCCTAT TTTACAAGAT GGTGCAACAA CTGGGCAAGG CAGAAGCCGC 3960 TGCCCTCACT GAAACAGCAA AACAGGTATA CTTCAAAAGA AATTATCCAC ATATTGGTCA 4020 CACTGACCAC ATGGTTACAA ACACTTCCAA TGGACAGCCC TCGACCTTAA CTATTTTCGA 4080 GACAGCACTG TGAATCCAAC CAAAATGTCA AGTCCGTTCC GAAGGCATTT TCCACTAGTT 4140 TTTGGACTAT GTAAACCACA TTGTACTTTT TTTTACTTTG GCAACAAATA TTTATACATA 4200 CAAGATGCTA GTTCATTTGA ATATTTCTCC C
Seq ID NO: 572 Protein εequence Protein Accession ft: AAC27076.1
11 21 31 41 51
MLPVYQEVKP NPLQDANICS RVFFWWLNPL FKIGHKRRLE EDDMYSVLPE DRSQHLGEEL 60 QCFWDKEVLR AENDAQKPSL TRAIIKCYWK SYLVLGIFTL IEESAKVIQP IFLGKIINYF 120 ENYDPMDSVA LNTAYAYATV LTFCTLILAI LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR 180 LSNMAMGKTT TGQIVNLLSN DVNKFDQVTV FLHFLWAGPL QAIAVTALLW MEIGISCLAG 240 MAVLIILLPL QSCFGKLFSS LRSKTATFTD ARIRTMNEVI TGIRIIKMYA WEKSFSNLIT 300 NLRKKEISKI LRSSCLRGMN LASFFSASKI IVFVTFTTYV LLGSVITASR VFVAVTLYGA 360 VRLTVTLFFP SAIERVSEAI VSIRRIQTFL LLDEISQRNR QLPSDGKKMV HVQDFTAFWD 420 KASETPTLQG LSFTVRPGEL LAWGPVGAG KSSLLSAVLG ELAPSHGLVS VHGRIAYVSQ 480 QPWVFSGTLR SNILFGKKYE KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGTTLSGGQK 540 ARVNLARAVY QDADIYLLDD PLSAVDAEVS RHLFELCICQ ILHEKITILV THQLQYLKAA 600 SQILILKDGK MVQKGTYTEF LKSGIDFGSL LKKDNEESEQ PPVPGTPTLR NRTFSESSVW 660 SQQSSRPSLK DGALESQDTE NVPVTLSEEN RSEGKVGFQA YKNYFRAGAH WIVFIFLILL 720 NTAAQVAYVL QDWWLSYWAN KQSMLNVTVN GGGNVTEKLD LNWYLGIYSG LTVATVLFGI 780 ARSLLVFYVL VNSSQTLHNK MFESILKAPV LFFDRNPIGR ILNRFSKDIG HLDDLLPLTF 840 LDFIQTLLQV VGWSVAVAV IPWIAIPLVP LGIIFIFLRR YFLETSRDVK RLESTTRSPV 900 FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV RLDAICAMFV 960 IIVAFGSLIL AKTLDAGQVG LALSYALTLM GMFQWCVRQS AEVENMMISV ERVIEYTDLE 1020 KEAPWEYQKR PPPAWPHEGV IIFDNVNFMY SPGGPLVLKH LTALIKSQEK VGIVGRTβAG 1080 KSSLISALFR LSEPEGKIWI DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFKE 1140 HTDEELWNAL QEVQLKETIE DLPGKMDTEL AESGSNFSVG QRQLVCLARA ILRKNQILII 1200 DEATANVDPR TDELIQKKIR EKFAHCTVLT lAHRLNTIID SDKIMVLDSG RLKEYDEPYV 1260 LLQNKESLFY KMVQQLGKAE AAALTETAKQ VYFKRNYPHI GHTDHMVTNT SNGQPSTLTI 1320 FETAL
Seq ID NO: 573 DNA sequence Nucleic Acid Accession ft: Eos sequence Coding sequence: 1..1365
60
120
180
Figure imgf001174_0001
240
GATGCTCTCA CAAAAACAAA TATAATATTT GTTGCTATAC ACAGAGAACA TTATACCTCC 300
CTGTGGGACC TGAGACATCT GCTTGTGGGT AAAATCCTGA TTGATGTGAG CAATAACATG 360
AGGATAAACC AGTACCCAGA ATCCAATGCT GAATATTTGG CTTCATTATT CCCAGATTCT 420
TTGATTGTCA AAGGATTTAA TGTTGTCTCA GCTTGGGCAC TTCAGTTAGG ACCTAAGGAT 480
GCCAGCCGGC AGGTTTATAT ATGCAGCAAC AATATTCAAG CGCGACAACA GGTTATTGAA 540
CTTGCCCGCC AGTTGAATTT CATTCCCATT GACTTGGGAT CCTTATCATC AGCCAGAGAβ 600
ATTGAAAATT TACCCCTACG ACTCTTTACT CTCTGGAGAβ GGCCAGTGGT GGTAGCTATA 660
AGCTTGGCCA CATTTTTTTT CCTTTATTCC TTTGTCAGAG ATGTGATTCA TCCATATGCT 720
AGAAACCAAC AGAGTGACTT TTACAAAATT CCTATAGAGA TTGTGAATAA AACCTTACCT 780
ATAGTTGCCA TTACTTTGCT CTCCCTAGTA TACCTCGCAG GTCTTCTGGC AGCTGCTTAT 840
CAACTTTATT ACeβCACCAA GTATAGGAGA TTTCCACCTT GGTTGGAAAC CTGGTTACAG 900
TGTAGAAAAC AGCTTGGATT ACTAAGTTTT TTCTTCGCTA TGGTCCATGT TGCCTACAGC 960
CTCTGCTTAC CGATGAGAAG GTCAGAGAGA TATTTGTTTC TCAACATGGC TTATCAGCAG 1020
GTTCATGCAA ATATTGAAAA CTCTTGGAAT GAGGAAGAAG TTTGGAGAAT TGAAATGTAT 1080
ATCTCCTTTG GCATAATGAG CCTTGGCTTA CTTTCCCTCC TGGCAGTCAC TTCTATCCCT 1140
TCAGTGAβCA ATGCTTTAAA CTGGAGAGAA TTCAGTTTTA TTCAGTCTAC ACTTGGATAT 1200
GTCGCTCTGC TCATAAGTAC TTTCCATGTT TTAATTTATG GATGGAAACG AGCTTTTGAG 1260
GAAGAGTACT ACAGATTTTA TACACCACCA AACTTTGTTC TTGCTCTTGT TTTGCCCTCA 1320
ATTGTAATTC TGGATCTTTT GCAGCTTTGC AGATACCCAG ACTGA
Seq ID NO: 574 Protein εequence
Protein Accession ft: Eos εequence
1 11 21 31 41 51
1 1 | 1 | 1 |1 | 1 | 1 MESISMMGSP KSLSETCLPN GINGIKDARK VTVGVIGSGD FAKSLTIRLI RCGYHWIGS 60
RNPKFASEFF PHWDVTHHE DALTKTNIIF VAIHREHYTS LWDLRHLLVG KILIDVSNNM 120
RINQYPESNA EYLASLFPDS LIVKGFNWS AWALQLGPKD ASRQVYICSN NIQARQQVIE 180
LARQLNFIPI DLGSLSSARE IENLPLRLFT LWRGPVWAI SLATFFFLYS FVRDVIHPYA 240
RNQQSDFYKI PIEIVNKTLP IVAITLLSLV YLAGLLAAAY QLYYGTKYRR FPPWLETWLQ 300
CRKQLGLLSF FFAMVHVAYS LCLPMRRSER YLFLNMAYQQ VHANIENSWN EEEVWRIEMY 360
ISFGIMSLGL LSLLAVTSIP SVSNALNWRE FSFIQSTLGY VALLISTFHV LIYGWKRAFE 420
EEYYRFYTPP NFVLALVLPS IVILDLLQLC RYPD Seq ID NO: 575 DNA sequence
Nucleic Acid Accesεion it: NM_001873.1
Coding sequence: 3..1721
1 11 21 31 41 51
I I I I I I
AAATGGCGTG CCCGTCTCTC CGCCGGCCCC CTGCCTCGCA GTGGTTTCTC CTGCAGCTCC 60
CCTGGGCTCC GCGGCCAGTA GTGCAGCCCG TGGAGCCGCG GCTTTGCCCG TCTCCTCTGG 120 0 GTGGCCCCAG TGCGCGGGCT GACACTCATT CAGCCGGGGA AGβTGAGGCG AGTAGAGGCT 180
GβTGCGGAAC TTGCCβCCCC CAGCAGCGCC ββCGGGCTAA GCCCAGGGCC GGβCAβACAA 240
AAβAGGCCCC CCGCGTAβGA AGGCACGGCC GGCGGCGGCG GAβCGCAGCG ATGβCCGβGC 300 βAβββGGCAG CGCβCTGCTG GCTCTGTGCG ββGCACTGGC TGCCTGCGGG TβGCTCCTGG 360
GCGCCGAAGC CCAGGAGCCC GGGGCGCCCG CGGCGGGCAT GAGβCGGCGC CGβCGGCTGC 420 5 AGCAAGAGGA CGGCATCTCC TTCGAGTACC ACCGCTACCC CGAGCTGCGC βAββCGCTCG 480
TGTCCGTGTG GCTGCAGTGC ACCGCCATCA GCAGGATTTA CACGGTGGGG CGCAGCTTCG 540
AGGGCCGGGA GCTCCTGGTC ATCGAGGTGT CCGACAACCC TGGCGTCCAT GAGCCTGGTG 600
AGCCTGAATT TAAATACATT GGGAATATGC ATGGGAATGA GGCTGTTGGA CGAGAACTGC 660
TCATTTTCTT GGCCCAGTAC CTATGCAACG AATACCAGAA GGGGAACGAG ACAATTGTCA 720 0 ACCTGATCCA CAGTACCCGC ATTCACATCA TGCCTTCCCT GAACCCAGAT GGCTTTGAGA 780
AGGCACCβTC TGAGCCTGGT GAACTCAAGG ACTGGTTTGT ββGTCGAAGC AATGCCCAGG 840
GAATAGATCT GAACCGGAAC TTTCCAGACC TGGATAGGAT AGTGTACGTG AATGAGAAAG 900
AAGGTGGTCC AAATAATGAT CTGTTGAAAA ATATGAAGAA AATTGTGGAT CAAAACACAA 960
AGCTTGCTCC TGAGACCAAG GCTGTCATTC ATTGGATTAT GGATATTCCT TTTGTGCTTT 1020 5 CTGCCAATCT CCATGβAβGA GACCTTGTGG CCAATTATCC ATATGATGAG ACGCGGAGTβ 1080
GTAGT6CTCA CCAATACAGC TCCTCCCCAG ATβACGCCAT TTTCCAAAGC TTGGCCCGGG 1140
CATACTCTTC TTTCAACCCG GCCATGTCTβ ACCCCAATCG GCCACCATGT CGCAAGAATG 1200
ATGATGACAG CAGCTTTGTA GATββAACCA CCAACGCTGβ TGCTTGGTAC AGCGTACCTG 1260
GAGGGATGCA AGACTTCAAT TACCTTAGCA GCAACTGTTT TGAGATCACC GTGGAGCTTA 1320 0 GCTGTGAGAA GTTCCCACCT βAAβAGACTC TGAAGACCTA CTGGGAGGAT AACAAAAACT 1380
CCCTCATTAG CTACCTTGAG CAGATACACC GAGGAGTTAA AGGATTTGTC CGAGACCTTC 1440
AAGGTAACCC AATTGCGAAT GCCACCATCT CCGTGGAAGG AATAGACCAC GATGTTACAT 1500
CCGCAAAGGA TGGTGATTAC TGGAGATTGC TTATACCTGG AAACTATAAA CTTACAGCCT 1560
CAGCTCCAGG CTATCTGGCA'ATAACAAAGA AAGTGGCAGT TCCTTACAGC CCTGCTGCTG 1620 5 GGGTTGATTT TGAACTGGAG TCATTTTCTG AAAGGAAAGA AGAGGAGAAG GAAGAATTGA 1680
TGGAATGGTG GAAAATGATG TCAGAAACTT TAAATTTTTA AAAAGGCTTC TAGTTAGCTG 1740
CTTTAAATCT ATCTATATAA TGTAGTATGA TGTAATGTGG TCTTTTTTTT AGATTTTGTG 1800
CAGTTAATAC TTAACATTGA TTTATTTTTT AATCATTTAA ATATTAATCA ACTTTCCTTA 1860
AAATAAATAG CCTCTTAGGT AAAAATATAA GAACTTGATA TATTTCATTC TCTTATATAG 1920 0 TATTCATTTT CCTACCTATA TTACACAAAA AAGTATAGAA AAGATTTAAG TAATTTTGCC 1980
ATCCTAGGCT TAAATGCAAT ATTCCTGGTA TTATTTACAA TGCAGAATTT TTTGAGTAAT 2040
TCTAGCTTTC AAAAATTAGT GAAGTTCTTT TACTGTAATT GGTGACAATG TCACATAATG 2100
AATGCTATTG AAAAGGTTAA CAGATACAGC TCGGAGTTGT GAGCACTCTA CTGCAAGACT 2160
TAAATAGTTC AGTATAAATT GTCGTTTTTT TCTTGTGCTG ACTAACTATA AGCATGATCT 2220 5 TGTTAATGCA TTTTTGATGG GAAGAAAAGG TACATGTTTA CAAAGAGGTT TTATGAAAAG 2280
AATAAAAATT GACTTCTTGC TTGTACATAT AGGAGCAATA CTATTATATT ATGTAGTCCG 2340
TTAACACTAC TTAAAAGTTT AGGβTTTTCT CTTGGTTGTA GAGTGGCCCA GAATTGCATT 2400
CTGAATGAAT AAAGGTTAAA AAAAAATCCC CAGTGAAAAA AAA 0 Seq ID NO: 576 Protein sequence Protein Accession #: NP 001864.1
1 11 21 31 41 51
55 I I I I I I
MAGRGGSALL ALCβALAACG WLLGAEAQEP GAPAAGMRRR RRLQQEDGIS FEYHRYPELR 60
EALVSVWLQC TAISRIYTVG RSFEGRELLV IELSDNPGVH EPGEPEFKYI GNMHGNEAVG 120
RELLIFLAQY LCNEYQKGNE TIVNLIHSTR IHIMPSLNPD GFEKAASQPG ELKDWFVGRS 180
NAQGIDLNRN FPDLDRIVYV NEKEβGPNNH LLKNMKKIVD QNTKLAPETK AVIHWIMDIP 240
FVLSANLHGG DLVANYPYDE TRSGSAHEYS SSPDDAIFQS LARAYSSFNP AMSDPNRPPC 300
60 RKNDDDSSFV DGTTNGGAWY SVPGGMQDFN YLSSNCFEIT VELSCEKFPP EETLKTYWED 360
NKNSLISYLE QIHRGVKGFV RDLQGNPIAN ATISVEGIDH DVTSAKDGDY WRLLIPGNYK 420 LTASAPGYLA ITKKVAVPYS PAAGVDFELE SFSERKEEEK EELMEWWKMM SETLNF
Seq ID NO : 577 DNA sequence C Nucleic Acid Accession ff : Eos εequence
Coding sequence : 1 . . 933
1 11 21 31 41 51
™ /U A ITGTGCAGCA A ITGGACGGTG C IATCCCGGGC G ICCTGGCAGT G ITGACGGGCT G ICCTGACTGC 60
TTCGACAAGA GTGATGAGAA GGAGTGCCCC AAGGCTAAGT CGAAATGTGG CCCGACCTTC 120
TTCCCCTGTG CCAGCGGCAT CCATTGCATC ATTGGTCGCT TCCGGTGCAA TGGGTTTGAG 180
GACTGTCCCG ATGGCAGCGA TGAAGAGAAC TGCACAGCAA ACCCTCTGCT TTGCTCCACC 240
GCCCGCTACC ACTGCAAGAA CGGCCTCTGT ATTGACAAGA GCTTCATCTG CGATGGACAG 300
75 AATAACTGTC AAGACAACAβ TGATGAGGAA AGCTGTGAAA GTTCTCAAGA ACCCGGCAGT 360
GGGCAGGTGT TTGTβACTTC AGAGAACCAA CTTβTGTATT ACCCCAGCAT CACCTATGCC 420
ATCATCGGCA GCTCCGTCAT TTTTGTGCTG GTGGTGGCCC TGCTGGCACT GGTCTTGCAC 480
CACCAGCGGA AGCGGAACAA CCTCATGACG CTGCCCGTGC ACCGGCTGCA GCACCCTGTG 540
CTGCTGTCCC GCCTGGTGGT CCTGGACCAC CCCCACCACT GCAACGTCAC CTACAACGTC 600
80 AATAATGGCA TCCAGTATGT GGCCAβCCAG GCGGAGCAGA ATGCGTCGGA AβTAGGCTCC 660
CCACCCTCCT ACTCCGAGGC CTTGCTGGAC CAGAGGCCTG CGTGGTATGA CCTTCCTCCA 720
CCGCCCTACT CTTCTGACAC GGAATCTCTβ AACCAAGCCG ACCTGCCCCC CTACCGCTCC 80
CGGTCCGGGA GTGCCAACAG TGCCAGCTCC CAGGCAGCCA βCACCCTCCT GAGCGTGGAA 840
GACACCAGCC ACAGCCCGGG GCA6CCTGGC CCCCAGGAGβ GCACTGCTGA GCCCAGGβAC 900 TCTGAGCCCA GCCAGGGCAC TGAAGAAGTA TAA
Seq ID NO: 578 Protein sequence Protein Accession ft: Eos sequence
11 21 31 41 51
I I I I I
MCSNGRCIPG AWQCDβLPDC FDKSDEKECP KAKSKCGPTF FPCASGIHCI IGRFRCNGFE 60 DCPDGSDEEN CTANPLLCST ARYHCKNGLC IDKSFICDGQ NNCQDNSDEE SCESSQEPGS 120 GQVFVTSENQ LVYYPSITYA IIGSSVIFVL WALLALVLH HQRKRNNLMT LPVHRLQHPV 180 LLSRLWLDH PHHCNVTYNV NNGIQYVASQ AEQNASEVβS PPSYSEALLD QRPAWYDLPP 240 PPYSSDTESL NQADLPPYRS RSGSANSASS QAASSLLSVE DTSHSPGQPG PQEGTAEPRD 300 SEPSQGTEEV
Seq ID NO: 579 DNA sequence Nucleic Acid Accession ft: AF179274.1 Coding sequence: 1..1125
11 21 31 41 51
I I I I I
ATGβTβCTβT GGGAβTCCCC GCGβCAGTGC AGCAGCTGβA CACTTTGCGA GGGCTTTTGC 60 TGβCTβCTGC TGCTβCCCGT CATGCTACTC ATCGTAGCCC GCCCGGTGAA GCTCGCTGCT 120 TTCCCTACCT CCTTAAGTGA CTGCCAAACG CCCACCGGCT GGAATTGCTC TGGTTATGAT 180 GACAGAGAAA ATGATCTCTT CCTCTGTGAC ACCAACACCT GTAAATTTGA TGGGGAATGT 240 TTAAGAATTG GAGACACTGT GACTTGC6TC TGTCAGTTCA AGTGCAACAA TGACTATGTG 300 CCTGTGTGTG GCTCCAATGG CGAGAGCTAC CAGAATGAGT GTTACCTGCG ACAGGCTGCA 360 TGCAAACAGC AGAGTGA6AT ACTTGTGGTG TCAGAAGGAT CATGTGCCAC AGATGCAGGA 420 TCAGGATCTG GAGATGGAGT CCATGAAGGC TCTGGAβAAA CTAGTCAAAA GβAβACATCC 480 ACCTGTGATA TTTGCCAGTT TGGTGCAGAA TGTGACGAAG ATGCCGAGGA TGTCTGGTGT 540 GTGTGTAATA TTGACTGTTC TCAAACCAAC TTCAATCCCC TCTGCβCTTC TGATGGGAAA 600 TCTTATGATA ATGCATGCCA AATCAAAGAA GCATCGTGTC AβAAACAGGA GAAAATTGAA 660 GTCATGTCTT TGβGTCGATβ TCAAGATAAC ACAACTACAA CTACTAAGTC TGAAGATβGG 720 CATTATGCAA GAACAGATTA TGCAGAGAAT GCTAACAAAT TAGAAGAAAG TGCCAGAGAA 780 CACCACATAC CTTGTCCGGA ACATTACAAT GGCTTCTGCA TGCATGCGAA GTGTGAGCAT 840 TCTATCAATA TGCAGGAGCC ATCTTGCAGG TGTGATGCTG GTTATACTGG ACAACACTGT 900 GAAAAAAAGG ACTACAGTGT TCTATACGTT GTTCCCGGTC CTGTACGATT TCAGTATGTC 960 TTAATCGCAG CTGTGATTGG AACAATTCAG ATTGCTGTCA TCTGTGTGGT GGTCCTCTGC 1020 ATCACAAGGA AATGCCCCAG AAGCAACAGA ATTCACAGAC AGAAGCAAAA TACAGGGCAC 1080 TACAGTTCAG ACAATACAAC AAGAGCGTCC ACGAGGTTAA TCTGA
Seq ID NO: 580 Protein sequence Protein Accession ft: NP 057276.2
11 21 31 41 51
I I I I I
MVLWESPRQC SSWTLCEGFC WLLLLPVMLL IVARPVKLAA FPTSLSDCQT PTGWNCSGYD 60 DRENDLFLCD TNTCKFDGEC LRIGDTVTCV CQFKCNNDYV PVCGSNGESY QNECYLRQAA 120 CKQQSEILW SEGΞCATDAG SGSGDGVHEG SGETSQKETS TCDICQFGAE CDEDAEDVWC 180 VCNIDCSQTN FNPLCASDGK SYDNACQIKE ASCQKQEKIE VMSLGRCQDN TTTTTKSEDG 240 HYARTDYAEN ANKLEESARE HHIPCPEHYN GFCMHGKCEH SINMQEPSCR CDAGYTGQHC 300 EKKDYSVLYV VPGPVRFQYV LIAAVIGTIQ IAVICVWLC ITRKCPRSNR IHRQKQNTGH 360 YSSDNTTRAS TRLI
Seq ID NO: 581 DNA sequence Nucleic Acid Accession #: S78203.1 Coding sequence: 1..2190
11 21 31 41 51
I I I I I
ATGAATCCTT TCCAβAAAAA TGAGTCCAAG GAAACTCTTT TTTCACCTGT CTCCATTGAA 60 GAGGTACCAC CTCGACCACC TAGCCCTCCA AAGAAGCCAT CTCCGACAAT CTGTGGCTCC 120 AACTATCCAC TGAGCATTGC CTTCATTGTG GTGAATGAAT TCTGCGAGCG CTTTTCCTAT 180 TATGGAATGA AAGCTGTGCT GATCCTGTAT TTCCTβTATT TCCTGCACTG GAATGAAGAT 240 ACCTCCACAT CTATATACCA TGCCTTCAGC AβCCTCTGTT ATTTTACTCC CATCGTGGGA 300 GCAGCCATTG CTGACTCGTG GTTGGGAAAA TTCAAGACAA TCATCTATCT CTCCTTGGTG 360 TATGTGCTTG GCCATCTGAT CAAGTCCTTG GGTGCCTTAC CAATACTGGG AGGACAAGTG 420 GTACACACAG TCCTATCATT GATCGGCCTG AGTCTAATAG CTTTGGGGAC AGGAGGCATC 480 AAACCCTGTG TGGCAGCTTT TGGTGGAGAC CAGTTTGAAG AAAAACATGC AGAGGAACGG 540 ACTAGATACT TCTCAGTCTT CTACCTGTCC ATCAATGCAG GGAGCTTGAT TTCTACATTT 600 ATCACACCCA TGCTGAGAGG AGATGTGCAA TGTTTTGGAG AAGACTGCTA TGCATTGGCT 660 TTTGGA6TTC CAGGACTGCT CATGGTAATT GCACTTGTTG TGTTTGCAAT GGGAAGCAAA 720 ATATACAATA AACCACCCCC TGAAGGAAAC ATAGTGGCTC AAGTTTTCAA ATGTATCTGβ 780 TTT6CTATTT CCAATCGTTT CAAGAACCGT TCTGGAGACA TTCCAAAGCG ACAGCACTGG 840 CTAβACTCGG CAGCTGAGAA ATATCCAAAG CAGCTCATTA TGGATGTAAA GGCACTGACC 900 AGGGTACTAT TCCTTTATAT CCCATTGCCC ATGTTCTGGG CTCTTTTGGA TCAGCAGGGT 960 TCACGATGGA CTTTGCAAGC CATCAGGATG AATAGGAATT TGGGGTTTTT TGTGCTTCAG 1020 CCGGACCAGA TGCAGGTTCT AAATCCCTTT CTGGTTCTTA TCTTCATCCC GTTGTTTGAC 1080 TTTGTGATTT ATCGTCTGGT CTCCAAGTGT GGAATTAACT TCTCATCACT TAGGAAAATG 1140 GCTGTTGGTA TGATCCTAGC GTGCCTGGCA TTTGCAGTTG CGGCAβCTGT AGAGATAAAA 1200 ATAAATGAAA TG6CCCCAGC CCAGTCAGGT CCCCAGGAGG TTTTCCTACA AGTCTTGAAT 1260 CTG6CAGATG ATGAββTGAA GGTGACAGTG GTGGGAAATG AAAACAATTC TCTGTTGATA 1320 GAGTCCATCA AATCCTTTCA GAAAACACCA CACTATTCCA AACTGCACCT GAAAACAAAA 1380 AGCCAGGATT TTCACTTCCA CCTGAAATAT CACAATTTGT CTCTCTACAC TGAGCATTCT 1440 βTGCAGβAβA AGAACTGGTA CAGTCTTGTC ATTCGTGAAG ATGGGAACAG TATCTCCAGC 1500 ATGATGGTAA AGGATACAGA AAGCAAAACA ACCAATGGGA TGACAACCGT GAGGTTTGTT 1560
AACACTTTGC ATAAAGATGT CAACATCTCC CTGAGTACAG ATACCTCTCT CAATGTTGGT 1620
GAAGACTATG GTGTGTCTGC TTATAGAACT GTGCAAAGAG GAβAATACCC TGCAGTGCAC 1680
TGTAGAACAG AAGATAAGAA CTTTTCTCTG AATTTGGGTC TTCTAβACTT TGβTβCACCA 1740
TATCTGTTTG TTATTACTAA TAACACCAAT CAGGGTCTTC AGβCCTGβAA GATTGAAβAC 1800
ATTCCAGCCA ACAAAATGTC CATTGCGTGG CAGCTACCAC AATATβCCCT GGTTACAβCT 1860
GGGGAGGTCA TGTTCTCTGT CACAGGTCTT GAGTTTTCTT ATTCTCAGGC TCCCTCTAGC 1920
ATGAAATCTG TGCTCCAGGC AβCTTββCTA TTGACAATTG CAGTTGGGAA TATCATCGTG 1980
CTTGTTGTGG CACAGTTCAG TGGCCTGGTA CAGTGβGCCG AATTCATTTT GTTTTCCTGC 2040
CTCCTGCTGG TGATCTGCCT GATCTTCTCC ATCATGGGCT ACTACTATGT TCCTGTAAAG 2100
ACAGAGGATA TGCGGGGTCC AGCAGATAAG CACATTCCTC ACATCCAGGβ GAACATGATC 2160
AAACTAGAGA CCAAGAAGAC AAAACTCTGA
Seq ID NO: 582 Protein sequence
Protein Accession #: AAB34388.1
1 11 21 31 41 51
1 1 1 1 1 | 1 1 1 | 1 MNPFQKNESK ETLFSPVSIE EVPPRPPSPP KKPSPTICGS NYPLSIAFIV VNEFCERFSY 60
YGMKAVLILY FLYFLHWNED TSTSIYHAFS SLCYFTPILG AAIADSWLGK FKTIIYLSLV 120
YVLGHVIKSL GALPILGGQV VHTVLSLIGL SLIALGTGGI KPCVAAFGGD QFEEKHAEER 180
TRYFSVFYLS INAGSLISTF ITPMLRGDVQ CFGEDCYALA FGVPGLLMVI ALWFAMGSK 240
IYNKPPPEGN IVAQVFKCIW FAISNRFKNR SGDIPKRQHW LDWAAEKYPK QLIMDVKALT 300
RVLFLYIPLP MFWALLDQQG SRWTLQAIRM NRNLGFFVLQ PDQMQVLNPF LVLIFIPLFD 360
FVIYRLVSKC GINFSSLRKM AVGMILACLA FAVAAAVEIK INEMAPAQSG PQEVFLQVLN 420
LADDEVKVTV VGNENNSLLI ESIKSFQKTP HYSKLHLKTK SQDFHFHLKY HNLSLYTEHS 480
VQEKNWYSLV IREDGNSISS MMVKDTESKT TNGMTTVRFV NTLHKDVNIS LSTDTSLNVG 540
EDYGVSAYRT VQRGEYPAVH CRTEDKNFSL NLGLLDFGAA YLFVITNNTN QGLQAWKIED 600
IPANKMSIAW QLPQYALVTA GEVMFSVTGL EFSYSQAPSS MKSVLQAAWL LTIAVGNIIV 660
LWAQFSGLV QWAEFILFSC LLLVICLIFS IMGYYYVPVK TEDMRGPADK HIPHIQGNMI 720
KLETKKTKL
Seq ID NO: 583 DNA sequence
Nucleic Acid Accession ft: NM_032642.1 Coding sequence: 184..1263
11 21 31 41 51
I I | 1 | 1 | 1
GACCATTAGC AGGCACCCAG GCCTGTCTTT GGCTCGGAAA CGGTGGCCCC CAATCTAGCC 60
TAGTTTGAAC CTAGGAACTG CAGGACCAGA GAGATTCCAC TGGAGCCTGA TGβACGGGTG 120
ACAGAGβGAA CCCTACTCTG GAAACTGTCA GTCCCAGGGC ACTGGGGAGG GCTβAGGCCG 180
ACCATGCCCA βCCTGCTGCT GCTGTTCACG GCTGCTCTGC TGTCCAGCTβ GβCTCAGCTT 240
CTGACAGACG CCAACTCCTG CTGGTCATTA GCTTTGAACC CGGTGCAGAG ACCCGAGATG 300
TTTATCATCG GTβCCCAGCC CGTGTGCAGT CAGCTTCCCG GGCTCTCCCC TGGCCAGAGG 360
AAGCTGTGCC AATTGTACCA GGAβCACATG GCCTACATAG GGGAGGGAGC CAAGACTGGC 420
ATCAAGGAAT GCCAGCACCA GTTCCGβCAG CGGCGGTβGA ATTGCAGCAC AGCGGACAAC 480
GCATCTGTCT TTGGGAGAGT CATGCAGATA GGCAGCCGAG AGACCGCCTT CACCCACGCG 540
GTGAGCGCCG CGGGCGTGGT CAACGCCATC AGCCGGGCCT GCCGCGAGGβ CGAβCTCTCC 600
ACCTGCGGCT GCAGCCGGAC GGCGCGGCCC AAGGACCTGC CCCGGGACTG GCTGTGGGGC 660
GGCTGTGGGG ACAACGTGGA GTACGGCTAC CGCTTCGCCA AGGAGTTTGT GGATβCCCGG 720
GAGCGAGAGA AGAACTTTGC CAAAGGATCA GAGGAGCAGG GCCGGβTGCT CATGAACCTG 780
CAAAACAACG AGGCCGGTCG CAGGβCTGTG TATAAGATGG CAGACGTAGC CTGCAAATGC 840
CACGGCGTCT CGGGGTCCTG CAGCCTCAAG ACCTGCTβGC TGCAGCTGGC CGAGTTCCGC 900
AAGGTCG6GG ACCGGCTGAA GGAGAAGTAC GACAGCGCGG CCGCCATGCG CGTCACCCGC 960
AAGGGCCGGC TGGAGCTGGT CAACAGCCGC TTCACCCAGC CCACCCCGGA GGACCTGGTC 1020
TATGTGGACC CCAGCCCCGA CTACTGCCTG CGCAACGAGA CCACGGGCTC CCTGGGCACG 1080
CAGGGCCGCC TCTGCAACAA GACCTCGGAG GGCATGGATG GCTGTGAβCT CATGTGCTGC 1140
GGGCGTGGCT ACAACCAGTT CAAGAGCGTG CAGGTGGAGC GCTGCCACTG CAAGTTCCAC 1200
TGGTGCTGCT TCGTCAGGTG TAAGAAGTGC ACGGAGATCG TGGACCAGTA CATCTGTAAA 1260
TAGCCCGGAG GGCCTGCTCC CGβCCCCCCC TGCACTCTGC CTCACAAAGG TCTATATTAT 1320
ATAAATCTAT ATAAATCTAT TTTATATTTG TATAAGTAAA TGGGT6GGTG CTATACAATG 1380
GAAAGATGAA AATGGAAAGG AAGAGCTTAT TTAAGAGACG CTGGAGATCT CTGAGGAGTG 1440
GACTTTGCTG GTTCTCTCCT CTTGGTGGGT GGGAGACAGG GCTTTTTCTC TCCCTCTGGC 1500
GAGGACTCTC AGGATGTAGG GACTTGGAAA TATTTACTGT CTGTCCACCA CGGCCTGGAG 1560
GAGGGAGGTT GTGGTTGGAT GGAGGAGATG ATCTTGTCTG GAAGTCTAGA GTCTTTGTTG 1620
GTTAGAGGAC TGCCTGTGAT CCTGGCCACT AGGCCAAGAG GCCCTATGAA GGTGGCGGGA 1680
ACTCAGCTTC AACCTCGATG TCTTCAGGGT CTTGTCCAGA ATGTAGATGG GTTCCGTAAG 1740
AGβCCTGGTG CTCTCTTACT CTTTCATCCA CGTGCACTTG TGCGGCATCT GCAGTTTACA 1800
GGAACGGCTC CTTCCCTAAA ATGAGAAGTC CAACGTCATC TCTGGCCCAG TGACCACAGA 1860
GAGATCTGCA CCTCCCGGAC TTCAGGCCTG CCTTTCCAGC GAGAATTCTT CATCCTCCAC 1920
GGTTCACTAG CTCCTACCTG AAGAGGAAAG GGGGCCATTT GACCTGACAT GTCAGGAAAG 1980
CCCTAAACTG AATGTTTGCG CCTGGGCTGC AGAAGCCAGG GTGCATGACC AGGCTGCGTG 2040 βACGTTATAC TGTCTTCCCC CACCCCCGGG GAGGGGAAGC TTGAGCTGCT GCTGTCACTC 2100
CTCCACCGAG GGAGGCCTCA CAAACCACAG GACGCTGCAA CGGGTCAGGC TGGCGGGCCC 2160
GGCGTGCTCA TCATCTCTGC CCCAGGTGTA . CGGTTTCTCT CTGACATTAA ATGCCCTTCA 2220
TGGAAAAAAA AAAAAGAAAA AAAAAAAAAA . AA
Seq ID NO: 584 Protein sequence Protein Accession ft: NP_116031.1
1 11 21 31 41 51
I I I I I I
MPSLLLLFTA ALLSSWAQLL TDANSWWSLA LNPVQRPEMF IIGAQPVCSQ LPGLSPGQRK 60 LCQLYQEHMA YIGEGAKTGI KECQHQFRQR RWNCSTADNA SVFGRVMQIG SRETAFTHAV 120 SAAGWNAIS RACREGELST CGCSRTARPK DLPRDWLWGG CGDNVEYGYR FAKEFVDARE 180
REKNFAKGSE EQGRVLMNLQ NNEAGRRAVY KMADVACKCH GVSGSCSLKT CWLQLAEFRK 240
VGDRLKEKYD SAAAMRVTRK GRLELVNSRF TQPTPEDLVY VDPSPDYCLR NESTGSLβTQ 300
GRLCNKTSEG MDGCELMCCG RβYNQFKSVQ VERCHCKFHW CCFVRCKKCT EIVDQYICK
Seq ID NO: 585 DNA sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..1479
11 21 31 41 51
I I I I
ATGGCTTTGA ACTCAGGGTC ACCACCAGCT ATTGGACCTT ACTATGAAAA CCATGGATAC 60 CAACCGGAAA ACCCCTATCC CGCACAGCCC ACTGTGGTCC CCACTGTCTA CGAGGTGCAT 120 CCGGCTCAGT ACTACCCGTC CCCCGTGCCC CAGTACGCCC CGAGGGTCCT GACGCAGGCT 180 TCCAACCCCG TCGTCTGCAC GCAGCCCAAA TCCCCATCCG GGACAGTGTG CACCTCAAAG 240 ACTAAGAAAG CACTGTGCAT CACCTTGACC CTGGGGACCT TCCTCGTGGG AGCTGCGCTG 300 GCCGCTGGCC TACTCTGGAA GTTCATGGGC AGCAAGTGCT CCAACTCTGC GATAGAGTGC 360 GACTCCTCAG GTACCTGCAT CAACCCCTCT AACTGGTGTG ATGGCGTGTC ACACTGCCCC 420 GGCGGGGAGG ACGAGAATCG GTGTGTTCGC CTCTACββAC CAAACTTCAT CCTTCAGGTG 480 TACTCATCTC AGAGGAAGTC CTGβCACCCT GTGTGCCAAG ACGACTGGAA CGAGAACTAC 540 GGGCGGGCGG CCTGCAGGGA CATβeβCTAT AAGAATAATT TTTACTCTAG CCAAGGAATA 600 GTGGATGACA βCGGATCCAC CAGCTTTATG AAACTGAACA CAAGTGCCGG CAATGTCGAT 660 ATCTATAAAA AACTGTACCA CAGTGATGCC TGTTCTTCAA AAGCAGTGGT TTCTTTACGC 720 TGTATAβCCT GCGGGGTCAA CTTGAACTCA AGCCGCCAGA GCAGGATCGT GGGCGGCGAG 780 AGCGCGCTCC CGGGGGCCTG GCCCTGGCAG GTCAGCCTGC ACGTCCAGAA CGTCCACβTG 840 TGCGGAGGCT CCATCATCAC CCCCGAGTGG ATCGTGACAG CGGCCCACTG CGTβGAAAAA 900 CCTCTTAACA ATCCATGGCA TTGGACGGCA TTTGCGGGGA TTTTGAβACA ATCTTTCATG 960 TTCTATGGAG CCGGATACCA AGTAGAAAAA GTGATTTCTC ATCCAAATTA TGACTCCAAG 1020 ACCAAGAACA ATGACATTGC GCTGATGAAG CTGCAGAAGC CTCTGACTTT CAACGACCTA 1080 GTGAAACCAG TGTGTCTGCC CAACCCAGGC ATGATGCTGC AGCCAGAACA GCTCTGCTGG 1140 ATTTCCGGGT GGGGGGCCAC CGAβGAGAAA GββAAGACCT CAGAAGTGCT GAACGCTGCC 1200 AAGGTGCTTC TCATTGAGAC ACAGAGATGC AACAGCAGAT ATGTCTATGA CAACCTGATC 1260 ACACCAGCCA TGATCTGTGC CGGCTTCCTG CAGGGGAACG TCGATTCTTG CCAGGβTβAC 1320 AGTGGAGGGC CTCTGGTCAC TTCGAAGAAC AATATCTG6T GGCTGATAGG GβATACAACC 1380 TGGGGTTCTG GCTGTGCCAA AGCTTACAGA CCAGGAGTGT ACGGGAATGT βATGGTATTC 1440 ACGGACTβGA TTTATCGACA AATGAGGGCA GACGGCTAA
Seq ID NO: 586 Protein sequence Protein Accession ft: Eos sequence
11 21 31 41 51
I I I I I
MALNSGSPPA IGPYYENHGY QPENPYPAQP TWPTVYEVH PAQYYPSPVP QYAPRVLTQA 60 SNPWCTQPK SPSGTVCTSK TKKALCITLT LGTFLVGAAL AAGLLWKFMG SKCSNSGIEC 120 DSSGTCINPS NWCDGVSHCP GGEDENRCVR LYGPNFILQV YSSQRKSWHP VCQDDWNENY 180 GRAACRDMGY KNNFYSSQGI VDDSGSTSFM KLNTSAGNVD IYKKLYHSDA CSSKAWSLR 240 CIACGVNLNS SRQSRIVββE SALPGAWPWQ VSLHVQNVHV CGGSIITPEW IVTAAHCVEK 300 PLNNPWHWTA FAGILRQSFM FYGAGYQVEK VISHPNYDSK TKNNDIALMK LQKPLTFNDL 360 VKPVCLPNPG MMLQPEQLCW ISGWGATEEK GKTSEVLNAA KVLLIETQRC NSRYVYDNLI 420 TPAMICAGFL QGNVDSCQGD SGGPLVTSKN NIWWLIGDTS WGSGCAKAYR PGVYGNVMVF 480 TDWIYRQMRA DG
Seq ID NO: 587 DNA sequence
Nucleic Acid Accession #: NM_005656.1
Coding sequence: 57..1535
11 21 31 41 51
I I I I
GTCATATTGA ACATTCCAGA TACCTATCAT TACTCGATGC TGTTGATAAC AGCAAGATGG 60 CTTTGAACTC AGGGTCACCA CCAGCTATTG GACCTTACTA TGAAAACCAT GβATACCAAC 120 CGGAAAACCC CTATCCCGCA CAGCCCACTG TGGTCCCCAC TGTCTACGAG GTGCATCCGG 180 CTCAGTACTA CCCGTCCCCC GTGCCCCAGT ACGCCCCGAG GGTCCTGACG CAGGCTTCCA 240 ACCCCGTCGT CTGCACGCAG CCCAAATCCC CATCCGGGAC AGTGTGCACC TCAAAGACTA 300 AGAAAGCACT GTGCATCACC TTGACCCTGG GGACCTTCCT CGTGGGAGCT GCGCTGGCCG 360 CTGGCCTACT CTGGAAGTTC ATGGGCAGCA AGTGCTCCAA CTCTGGGATA GAGTGCGACT 420 CCTCAGGTAC CTGCATCAAC CCCTCTAACT GGTGTCATGG CGTβTCACAC TGCCCCGGCG 480 GGGAGGACGA GAATCGGTGT GTTCGCCTCT ACβCACCAAA CTTCATCCTT CAGATGTACT 540 CATCTCAGAG GAAGTCCTGG CACCCTGTGT GCCAAGACGA CTGGAACGAG AACTACGGGC 600 GGGCGGCCTG CAGGGACATG GGCTATAAGA ATAATTTTTA CTCTAGCCAA GGAATAGTGG 660 ATGACAGCGG ATCCACCAGC TTTATGAAAC TGAACACAAG TGCCGGCAAT GTCGATATCT 720 ATAAAAAACT GTACCACAGT GATGCCTGTT CTTCAAAAGC AGTGGTTTCT TTAC6CTGTT 780 TAGCCTGCGG GGTCAACTTG AACTCAAGCC GCCAGAGCAG GATCGTGGGC GGTGAGAGCG 840 CGCTCCCGGG GGCCTGβCCC TGGCAGGTCA GCCTGCACGT CCAGAACGTC CACGTGTβCG 900 GAGGCTCCAT CATCACCCCC GAGTGGATCC TGACAGCCGC CCACTGCGTG GAAAAACCTC 960 TTAACAATCC ATβGCATTGG ACGGCATTTG CGGGGATTTT GAGACAATCT TTCATGTTCT 1020 ATGGAGCCGG ATACCAAGTA CAAAAAGTGA TTTCTCATCC AAATTATGAC TCCAAGACCA 1080 AGAACAATGA CATTβCCCTβ ATGAAGCTGC AGAAGCCTCT GACTTTCAAC GACCTAGTβA 1140 AACCAGTGTG TCTGCCCAAC CCAGGCATGA TGCTGCAGCC AGAACACCTC TGCTGGATTT 1200 CCGGGTGGGG GGCCACCGAG GAGAAAGGGA AGACCTCAGA AGTGCTGAAC GCTGCCAAGG 1260 TGCTTCTCAT TGAGACACAG AGATGCAACA GCAGATATGT CTATGACAAC CTGATCACAC 1320 CAGCCATGAT CTGTGCCGGC TTCCTGCAGG GGAACGTCGA TTCTTGCCAG GGTGACAGTG 1380 GAGGGCCTCT GGTCACTTCG AACAACAATA TCTGGTGGCT GATAGGGGAT ACAAGCTGGG 1440 GTTCTGGCTG TGCCAAAGCT TACAGACCAG GAGTGTACGG GAATGTGATG GTATTCACGG 1500 ACTGGATTTA TCGACAAATG AAGGCAAACG GCTAATCCAC ATGGTCTTCG TCCTTGACGT 1560 CGTTTTACAA GAAAACAATβ GGGCTGGTTT TGCTTCCCCG TGCATGATTT ACTCTTAGAG 1620 ATGATTCAGA GGTCACTTCA TTTTTATTAA ACAGTGAACT TGTCTGGCTT TGGCACTCTC 1680 TGCCATACTC TGCAGGCTGC AGTGGCTCCC CTGCCCAGCC TGCTCTCCCT AACCCCTTGT 1740 CCGCAAGGGG TGATGGCCGG CTGGTTGTGG GCACTGGCGβ TCAATTGTGG AAGGAAGAGG 1800 GTTGGAGGCT GCCCCCATTG AGATCTTCCT GCTGAGTCCT TTCCAGGGGC CAATTTTGGA 1860 TGAGCATGGA GCTGTCACTT CTCAGCTGCT GGATGACTTG AGATGAAAAA GGAGAGACAT 1920 GGAAAGGGAG ACAGCCAGGT GGCACCTGCA GCGGCTGCCC TCTGGGGCCA CTTGGTAGTG 1980 TCCCCAGCCT ACTTCACAAG GGGATTTTβC TGATGGGTTC TTAGAGCCTT AGCAGCCCTG 2040 GATββTβGCC AGAAATAAAG GGACCAGCCC TTCATGGGTG GTGACGTGGT AGTCACTTGT 2100 AAGGGβAACA GAAACATTTT TGTTCTTATG GGGTGAGAAT ATAGACAGTG CCCTTGGTGC 2160 GAGGGAAGCA ATTGAAAAGG AACTTGCCCT GAGCACTCCT GGTGCAGGTC TCCACCTGCA 2220 CATTGGGTGβ GGCTCCTGGG AGGGAGACTC ACCCTTCCTC CTCATCCTCC CTGACCCTGC 2280 TCCTAGCACC CTGGAGAGTG AATGCCCCTT GGTCCCTGGC AGG6CGCCAA GTTTGGCACC 2340 ATGTCGGCCT CTTCAGGCCT GATAGTCATT GGAAATTGAG GTCCATGGGG GAAATCAAGG 2400 ATGCTCAGTT TAAGGTACAC TGTTTCCATG TTATGTTTCT ACACATTGAT GGTGβTGACC 2460 CTGAGTTCAA AβCCATCTT
Seq ID NO: 588 Protein sequence Protein Accession #: NP_005647.1
11 21 31 41 51
MALNSGSPPA IGPYYENHβY QPENPYPAQP TWPTVYEVH PAQYYPSPVP QYAPRVLTQA 60 SNPWCTQPK SPSGTVCTSK TKKALCITLT LGTFLVGAAL AAGLLWKFMG SKCSNSGIEC 120 DSSGTCINPS NWCDGVSHCP GGEDENRCVR LYGPNFILQM YSSQRKSWHP VCQDDWNENY 180 GRAACRDMGY KNNFYSSQGI VDDSGSTSFM KLNTSAGNVD IYKKLYHSDA CSSKAWSLR 240 CLACGVNLNS SRQSRIVGGE SALPGAWPWQ VSLHVQNVHV CGGSIITPEW IVTAAHCVEK 300 PLNNPWHWTA FAGILRQSFM FYGAGYQVQK VISHPNYDSK TKNNDIALMK LQKPLTFNDL 360 VKPVCLPNPG MMLQPEQLCW ISGWGATEEK GKTSEVLNAA KVLLIETQRC NSRYVYDNLI 420 TPAMICAGFL QGNVDSCQGD SGGPLVTSNN NIWWLIGDTS WGSGCAKAYR PGVYGNVMVF 480 TDWIYRQMKA NG
Seq ID NO: 589 DNA sequence
Nucleic Acid Accession ff: NM_001935.1
Coding sequence: 1..2301
11 21 31 41 51
ATGAAGACAC CGTGGAAGAT TCTTCTGGGA CTGCTGGGTG CTGCTGCβCT TGTCACCATC 60
ATCACCGTGC CCGTGGTTCT GCTGAACAAA GGCACAGATβ ATGCTACAGC TGACAGTCGC 120
AAAACTTACA CTCTAACTGA TTACTTAAAA AATACTTATA GACTGAAGTT ATACTCCTTA 180
AGATGGATTT CAGATCATGA ATATCTCTAC AAACAAβAAA ATAATATCTT GGTATTCAAT 240
GCTGAATATG GAAACAGCTC AGTTTTCTTG GAGAACAGTA CATTTGATβA GTTTGGACAT 300
TCTATCAATG ATTATTCAAT ATCTCCTGAT GGGCAGTTTA TTCTCTTAGA ATACAACTAC 360
GTGAAGCAAT GGAGGCATTC CTACACAGCT TCATATGACA TTTATGATTT AAATAAAAGG 420
CAGCTGATTA CAGAAGAGAG GATTCCAAAC AACACACAGT GββTCACATG GTCACCAGTG 480
GGTCATAAAT TGGCATATGT TTGGAACAAT GACATTTATG TTAAAATTGA ACCAAATTTA 540
CCAAGTTACA GAATCACATG GACGGΘ3AAA GAAGATATAA TATATAATGG AATAACTGAC 600
TGGGTTTATG AAGAGGAAGT CTTCAGTGCC TACTCTGCTC TGTGGTGGTC TCCAAACGGC 660
ACTTTTTTAG CATATGCCCA ATTTAACGAC ACAGAAβTCC CACTTATTβA ATACTCCTTC 720
TACTCTGATβ AGTCACTGCA GTACCCAAAG ACTGTACGGG TTCCATATCC AAAGGCAGGA 780
GCTGTβAATC CAACTGTAAA GTTCTTTGTT GTAAATACAG ACTCTCTCAG CTCAGTCACC 840
AATGCAACTT CCATACAAAT CACTGCTCCT GCTTCTATGT TGATAGGGGA TCACTACTTβ 900
TGTGATGTGA CATGGGCAAC ACAAGAAAGA ATTTCTTTGC AGTGGCTCAG GAGGATTCAG 960
AACTATTCGG TCATGGATAT TTGTβACTAT GATGAATCCA GTGGAAGATG GAACTGCTTA 1020
GTGGCACGGC AACACATTGA AATGAGTACT ACTGGCTGGG TTGGAAGATT TAGGCCTTCA 1080
GAACCTCATT TTACCCTTGA TGGTAATAGC TTCTACAAGA TCATCAGCAA TGAAGAAGGT 1140
TACAGACACA TTTGCTATTT CCAAATAGAT AAAAAAGACT GCACATTTAT TACAAAAGGC 1200
ACCTGGGAAG TCATCGGGAT AGAAGCTCTA ACCAGTGATT ATCTATACTA CATTAGTAAT 1260
GAATATAAAG GAATβCCAGG AGGAAGGAAT CTTTATAAAA TCCAACTTAG TGACTATACA 1320
AAAGTGACAT GCCTCAGTTG TGAGCTGAAT CCGGAAAGGT GTCAGTACTA TTCTGTGTCA 1380
TTCAGTAAAG AGGCGAAGTA TTATCAGCTG AGATGTTCCG GTCCTGGTCT GCCCCTCTAT 1440
ACTCTACACA GCAGCGTGAA TGATAAAGGG CTGAGAGTCC TGGAAGACAA TTCAGCTTTG 1500
GATAAAATGC TGCAGAATGT CCAGATGCCC TCCAAAAAAC TGGACTTCAT TATTTTGAAT 1560
GAAACAAAAT TTTGβTATCA GATGATCTTG CCTCCTCATT TTGATAAATC CAAGAAATAT 1620
CCTCTACTAT TAGATGTGTA TGCAGGCCCA TβTAβTCAAA AAGCAGACAC TGTCTTCAGA 1680
CTGAACTGGG CCACTTACCT TGCAAGCACA GAAAACATTA TAGTAGCTAG CTTTGATββC 1740
AGAGGAAGTG GTTACCAAGG AGATAAGATC ATGCATβCAA TCAACAGAAG ACTGGGAACA 1800
TTTGAAGTTG AAGATCAAAT TGAAGCAGCC AβACAATTTT CAAAAATGGG ATTTGTGGAC 1860
AACAAAC6AA TTGCAATTTG GGGCTGGTCA TATGGAGGGT ACGTAACCTC AATGGTCCTG 1920
GGATCGβGAA GTGGCGTGTT CAAGTGTGGA ATAGCCGTGG CGCCTGTATC CCGGTGGGAG 1980
TACTATGACT CAGTGTACAC AGAACGTTAC ATGGGTCTCC CAACTCCAGA AGACAACCTT 2040
GACCATTACA GAAATTCAAC AGTCATGAGC AGAGCTGAAA ATTTTAAACA AGTTGAGTAC 2100
CTCCTTATTC ATGGAACAGC AGATGATAAC GTTCACTTTC AGCAGTCAGC TCAGATCTCC 2160
AAAGCCCTGG TCGATGTTGG AGTGGATTTC CAGGCAATGT GGTATACTGA TGAAGACCAT 2220
GGAATAGCTA GCAGCACAGC ACACCAACAT ATATATACCC ACATGAGCCA CTTCATAAAA 2280
CAATGTTTCT CTTTACCTTA G
Seq ID NO: 590 Protein sequence Protein Accession #: NP 001926.1
1 11 21 31 41 51
I I I I I I
MKTPWKILLG LLGAAALVTI ITVPWLLNK GTDDATADSR KTYTLTDYLK NTYRLKLYSL RWISDHEYLY KQENNILVFN AEYGNSSVFL ENSTFDEFGH SINDYSISPD GQFILLEYNY 120 VKQWRHSYTA SYDIYDLNKR QLITEERIPN NTQWVTWSPV GHKLAYVWNN DIYVKIEPNL 180 PSYRITWTGK EDIIYNGITD WVYEEEVFSA YSALWWSPNG TFLAYAQFND TEVPLIEYSF 240 YSDESLQYPK TVRVPYPKAG AVNPTVKFFV VNTDSLSSVT NATSIQITAP ASMLIGDHYL 300 CDVTWATQER ISLQWLRRIQ NYSVMDICDY DESSGRWNCL VARQHIEMST TβWVβRFRPS 360 EPHFTLDGNS FYKIISNEEβ YRHICYFQID KKDCTFITKG TWEVIGIEAL TSDYLYYISN 420 EYKGMPGGRN LYKIQLSDYT KVTCLSCELN PERCQYYSVS FSKEAKYYQL RCSGPGLPLY 480 TLHSSVNDKG LRVLEDNSAL DKMLQNVQMP SKKLDFIILN ETKFWYQMIL PPHFDKSKKY 540 PLLLDVYAGP CSQKADTVFR LNWATYLAST ENIIVASFDG RGSGYQGDKI MHAINRRLGT 600 FEVEDQIEAA RQFSKMGFVD NKRIAIWGWS YGGYVTSMVL GSGSGVFKCG IAVAPVSRWE 660 YYDSVYTERY MGLPTPEDNL DHYRNSTVMS RAENFKQVEY LLIHGTADDN VHFQQSAQIS 720 KALVDVGVDF QAMWYTDEDH GIASSTAHQH IYTHMSHFIK QCFSLP
Seq ID NO: 591 DNA sequence Nucleic Acid Accession ff : NM_016077.1 Coding sequence: 128..667
1 11 21 31 41 51 1 1 | 1 | 1 | 1 1| | 1 TCGCTTTGTG ATTCTTGATC CGGAACTTTG TCACCCAGGA ACCCCGβAAG AGGTAGCTCA 60
CGCGATAGAA ACGTGTTCGC TTGCCCAGAA βAAGGGAAGβ CGCGAGTGAG GAAAGGAGGT 120
ACTGTAGATG CCCTCCAAAT CCTTGGTTAT GGAATATTTG GCTCATCCCA GTACACTCGG 180
CTTGGCTGTT GGAGTTGCTT GTGGCATGTβ CCTGGGCTGG AGCCTTCGAG TATGCTTTGG 240
GATGCTCCCC AAAAGCAAGA CGAGCAAGAC ACACACAGAT ACTGAAAGTG AAGCAAGCAT 300
CTTGGGAGAC AGCGGββAGT ACAAGATGAT TCTTGTGGTT CGAAATGACT TAAAGATGGG 360
AAAAGGGAAA GTββCTGCCC AGTβCTCTCA TGCTGCTGTT TCAGCCTACA AGCAGATTCA 420
AAGAAGAAAT CCTGAAATGC TCAAACAATβ GGAATACTGT GGCCAGCCCA AGGTGβTGGT 480
CAAAGCTCCT GATGAAGAAA CCCTGATTGC ATTATT6GCC CATGCAAAAA TGCTGGGACT 540
GACTGTAAGT TTAATTCAAG ATGCTGGACG TACTCAGATT GCACCAGGCT CTCAAACTGT 600
CCTAGGGATT GGGCCAGβAC CAGCAGACCT AATTGACAAA GTCACTGGTC ACCTAAAACT 660
TTACTAGGTG GACTTTGATA TGACAACAAC CCCTCCATCA CAAGTGTTTG AAGCCTGTCA 720
GATTCTAACA ACAAAAGCTG AATTTCTTCA CCCAACTTAA ATGTTCTTGA GATGAAAATA 780
AAACCTATTC CCATGTTCTA AAAAAA
Seq ID NO: 592 Prote:in sequence
Protein Accession ft : NP 057161.1
1 11 21 31 41 51
I I I I I I
MPSKSLVMEY LAHPSTLGLA VGVACGMCLG WSLRVCFGML PKSKTSKTHT DTESEASILG 60 DSGEYKMILV VRNDLKMGKG KVAAQCSHAA VSAYKQIQRR NPEMLKQWEY CGQPKVWKA 120 PDEETLIALL AHAKMLGLTV SLIQDAGRTQ IAPGSQTVLG IGPGPADLID KVTGHLKLY
Seq ID NO : 593 DNA sequence
Nucleic Acid Accession ft : FGENESH predicted
Coding sequence : 1 . .1896
11 21 31 41 51
I I I I I
ATGCGCGCCβ TGCCGCTGCC CGCCCCGCTC CTGCCGCTGC TGCTGCTCGC GCTCCTGGCC 60 GCTCCCGCCG CCCGCGCCAG CAGAGCCGAG TCCGTCTCCG CGCCGTGGCC CGAACCCGAG 120 CGCGAGTCGC GGCCACCGCC CββCCCGGGG CCCGGGAACA CCACCCGGTT TGGGTCTGGG 180 GCGGCGGGCG GCAGCGGCAG CTCCAGCTCC AACAGCAβTG GCGACGCCTT GGTGACCCGC 240 ATTTCCATCC TCCTCCCCGA CCTACCCACC CTCAAGGCAG CCGTGATCGT GGCGTTCGCC 300 TTTACCACCC TCCTCATCGC CTGCCTGCTG CTGCβCGTCT TCAGGTCGGG AAAGAGGTTA 360 AAGAAGACAC eCAAGTATGA TATCATCACC ACTCCAGCAG AGCGAGTGGA AATGGCGCCA 420 CTAAATGAAG AGGATGATGA AGATGAGGAC TCCACAGTAT TCGACATCAA ATACAGAGTG 480 TCCTTGCCGG CTGCACTGAG ACGTCAGCTG CCAGGGTGCC AGACGCTACT GACAGTTCCT 540 GTGCCCCCAC CCTTCATCCT CGACATTGAC CTTCCAGCAA GATGCAGTGG AAGGCCTGAT 600 GGTGGAATCA GACCTGGTAA AACCTGTTTC CCAGCCTGβT GGCATCCTGT GGAAAGTTGG 660 TCAGCTGCAA CCTGGGGTGT GAAGGACTGG ACCTGGAAGC CCTCTTGCβT CGGAGGTGTT 720 GAAACCAAAA CGAACβTTAT GTATAAAACC CCAGCTCCAT CGT6CGTGTC AGGCATCTGC 780 TCAGACTGTC ACTGβCAAGC TCGTTTCCAC GTCACCACAA TGGAGTTGCT TCTGCCACCC 840 TTTGGGCATC CCTTTAAAGT GCCCCCTACT TCTACTCCCC ATGGTTTTCG ACAACTGCAG 900 CTGAATCTCA TGGAAAAGCT GGATTCCTCT GCCTTACGCA GAAACACCCG GGCTCCATCT 960 GCCAGGTGCT TGCCACTGGT CCTGGCAGAA ATGGCGGCTG CTGAAAGTCA CCTTCCAAAT 1020 CCTTGGTGGC ACTTCAGCGC CACAGGCTCT CCAATAAAAA CCCTTTACAC ACAAACCATG 1080 AGTACCTTGG GCTTGGATGT TTTCTGTGGT GCCGGCCAGC GGGGCACCTT TTGTGAAGAC 1140 AGAGCAGTGA CTAAGGTTCT CCAβGGTAGC TCTTTCTCCA AACAGCTGCG CTGGAAGCCA 1200 GCCCTAGAGA GTGGGTTTCC CCATCATCTC AGGCTTCTCA GAGAGTGTCC TCCGCTGAGC 1260 ACCCATCCTG TCAGGTTGGC TCGTTCAGAT GCCCGGGGAC AAGCCAGCCT GACGGGGAGG 1320 AGGGTGTTTC GβCGTCCGCG GCAGTCTCTG CATGGCGGAG GGTCAGCGGG TACCGCAACT 1380 TGCCTTTTGG TTTTGAAGAT TCTGTTGAGG CGCCATCCTC ACCTTGACCT CTTCTACAAA 1440 ATCTGTCTCC CCTGCTGTGC CGTββAACAC CTACGGGAAG CCAAGAGAAG CTCAGTGACT 1500 GTCCTTGCGT CATTTGAGCA GAGCCCACAA AAGGCAGCTG CTGCCCACGG GGAGCCTGTC 1560 AAACGAGGGC CCAGTGGGCA ATTCACCAGA CACACATGCC CTGGCTGGGG GATCACACAT 1620 GCGAACCTGC AGACAATTCC AGATACCCAA GGCCAGGAAG GCCCACGTGA GGATGTCACT 1680 CACCCTGGAG GAGACTTGGA TGGβGTGGCA AATTTCTATT TGGAGGAAGA GGGTTTCCAG 1740 GATGGCAGAT GCCAGAAβAT GGTCCTGATG TCTGAGGAAG GGCCACCTAG TTTGACAGGA 1800 TGTGAGAGGC TCACAGGTTC CCATCACTTC TCCAGCCATT CCAAGTCTTG GTCCTTCCTT 1860 TCCCCCCGAC AGCCCCTβTT TCTGTCCAGG CCCTGA
Seq ID NO: 594 Protein sequence Protein Accession ft: FGENESH predicted 1 11 21 31 41 51 1 1 | 1 | 1 1 1 1 I 1
MRAVPLPAPL LPLLLLALLA APAARASRAE SVSAPWPEPE RESRPPPGPG PGNTTRFGSG 60
AAββSβSSSS NSSGDALVTR ISILLRDLPT LKAAVIVAFA FTTLLIACLL LRVFRSGKRL 120
KKTRKYDIIT TPAERVEMAP LNEEDDEDED STVFDIKYRV SLPAALRRQL PGCQTLLTVP 180
VPPPFILDID LPARCSGRPD eeiRPGKTCF PAWWHPVESW SAATWGVKDW TWKPSCVGGV 240
ETKTNVMYKT PAPSCVSGIC SDCHWQARFH VTTMELLLPP FGHPFKVPPT STPHGFRQLQ 300
LNLMEKLDSS ALRRNTRAPS ARCLPLVLAE MAAAESDLPN PWWHFSATGS PIKTLYTQTM 360
STLGLDVFCG AGQRGTFCED RAVTKVLQGS SFSKQLRWKP ALESGFPHHL RLLRECPPLS 420
THPVRLARSD ARGQASLTGR RVFRRPRQSL HGGGSAGTAT CLLVLKILLR RHPHLDLFYK 480
ICLPCCAVEH LREAKRSSVT VLASFEQSPQ KAAAAHGEPV KRGPSGQLTR HTCPGWGITH 540
ANLQTIPDTQ GQEGPREDVT HPGβDLDGVA NFYLEEEGFQ DGRCQKMVLM SEEGPPSLTG 600
CERLTβSHHF SSHSKSWSFL SPRQPLFLSR P
Seq ID NO: 595 DNA sc Ξquence
Nucleic Acid Accession ft: NM_021614.1 Coding sequence: 1..1740
11 21 31 41 51
ATGAGCAGCT GCAGGTACAA ceeβGGCGTc ATGCβGCCGC TCAβCAACTT GAGCGCGTCC 60 CGCCGGAACC TGCACGAGAT GGACTCAGAG GCβCAβCCCC TβCAβCCCCC CGCGTCTGTC 120 GGAGGAGGTG GCCGCGCGTC CTCCCCGTCT GCAGCCGCTG CCGCCGCCGC CGCTβTTTCβ 180 TCCTCAGCCC CCGAGATCGT GGTGTCTAAG CCCGAGCACA ACAACTCCAA CAACCTGGCG 240 CTCTATGGAA CCGGCGGCGG AGGCAGCACT GGAGGAGGCG GCGGCGGTGG CGGGAGCGGG 300 CACGGCAGCA GCAGTGGCAC CAAGTCCAGC AAAAAGAAAA ACCAGAACAT CGGCTACAAG 360 CTGGGCCACC GGCGCGCCCT βTTCGAAAAG CGCAAGCGGC TCAGCGACTA CGCGCTCATC 420 TTCGGCATGT TCGGCATCGT GGTCATGGTC ATCGAGACCG AβCTGTCGTG GβGCGCCTAC 480 GACAAGGCGT CGCTGTATTC CTTAGCTCTG AAATGCCTTA TCAβTCTCTC CACGATCATC 540 CTGCTCGGTC TGATCATCGT GTACCACGCC AGGGAAATAC AGTTGTTCAT GGTGGACAAT 600 GGAGCAGATG ACTGGAGAAT AGCCATGACT TATGAGCGTA TTTTCTTCAT CTGCTTGGAA 660 ATACTGGTGT GTGCTATTCA TCCCATACCT GGGAATTATA CATTCACATβ GACβGCCCGG 720 CTTGCCTTCT CCTATGCCCC ATCCACAACC ACCGCTGATG TG6ATATTAT TTTATCTATA 780 CCAAT6TTCT TAAGACTCTA TCTGATTGCC AGAGTCATβC TTTTACATAG CAAACTTTTC 840 ACTβATβCCT CCTCTAGAAG CATTGGAGCA CTTAATAAGA TAAACTTCAA TACACGTTTT 900 GTTATGAAβA CTTTAATGAC TATATGCCCA GGAACTGTAC TCTTGGTTTT TAGTATCTCA 960 TTATββATAA TTGCCGCATG GACTGTCCGA GCTTGTβAAA GGTACCATGA TCAACAGGAT 1020 GTTACTAGCA ACTTCCTTGG AGCGATGTGG TTβATATCAA TAACTTTTCT CTCCATTGGT 1080 TATββTGACA TGGTACCTAA CACATACTGT GGAAAAGGAG TCTGCTTACT TACTGGAATT 1140 ATGGβTGCTG GTTGCACAGC CCTGGTGGTA GCTGTAGTGG CAAGGAAGCT AGAACTTACC 1200 AAAGCAGAAA AACACGTGCA CAATTTCATG ATGβATACTC AGCTGACTAA AAGAGTAAAA 1260 AATGCAGCTG CCAATGTACT CAGGGAAACA TGGCTAATTT ACAAAAATAC AAAGCTAGTG 1320 AAAAAGATAG ATCATGCAAA AGTAAβAAAA CATCAACGAA AATTCCTGCA AGCTATTCAT 1380 CAATTAAGAA GTGTAAAAAT GGAGCAGAGG AAACTGAATG ACCAAGCAAA CACTTTGGTG 1440 GACTTGβCAA AGACCCAGAA CATCATGTAT GATATGATTT CTGACTTAAA CGAAAGGAGT 1500 GAAGACTTCG AGAAGAGGAT TGTTACCCTβ GAAACAAAAC TAGAGACTTT GATTGGTAGC 1560 ATCCACGCCC TCCCTGGGCT CATAAβCCAβ ACCATCAGGC AGCAGCAGAβ AGATTTCATT 1620 GAGGCTCAGA TGGAGAGCTA CGACAAGCAC GTCACTTACA ATβCTGAGCβ GTCCCGGTCC 1680 TCGTCCAGGA GβCGGCGGTC CTCTTCCACA GCACCACCAA CTTCATCAβA GAGTAGCTAβ
Seq ID NO: 596 Protein sequence Protein Accession it: NP_067627.1
11 21 31 41 51
I I I I I
MSSCRYNGGV MRPLSNLSAS RRNLHEMDSE AQPLQPPASV GGGGGASSPS AAAAAAAAVS 60 SSAPEIWSK PEHNNSNNLA LYGTGGGGST GGGGGGGGSG HGSSSGTKSS KKKNQNIGYK 120 LGHRRALFEK RKRLSDYALI FGMFβlWMV IETELSWGAY DKASLYSLAL KCLISLSTII 180 LLGLIIVYHA REIQLFMVDN GADDWRIAMT YERIFFICLE ILVCAIHPIP GNYTFTWTAR 240 LAFSYAPSTT TADVDIILSI PMFLRLYLIA RVMLLHSKLF TDASSRSIGA LNKINFNTRF 300 VMKTLMTICP GTVLLVFSIS LWIIAAWTVR ACERYHDQQD VTSNFLGAMW LISITFLSIG 360 YGDMVPNTYC GKGVCLLTGI MGAGCTALW AWARKLELT KAEKHVHNFM MDTQLTKRVK 420 NAAANVLRET WLIYKNTKLV KKIDHAKVRK HQRKFLQAIH QLRSVKMEQR KLNDQANTLV 480 DLAKTQNIMY DMISDLNERS EDFEKRIVTL ETKLETLIGS IHALPGLISQ TIRQQQRDFI 540 EAQMESYDKH VTYNAERSRS SSRRRRSSST APPTSSESS
Seq ID NO: 597 DNA sequence
Nucleic Acid Accession ft: NM_016029.1
Coding sequence: 228..1097
11 21 31 41 51
I I I I I
CTGCGATCCC GCAGGGCAGC GACGCGACTC TGGTGCGGGC CGTCTTCTTC CCCCCGAGCT 60 GGGCGTGCβC GGCCGCAATG AACTGGGAGC TGCTGCTGTG GCTGCTGGTG CTGTGCGCGC 120 TGCTCCTGCT CTTGGTGCAG CTGCTGC6CT TCCTGAGGGC TGACGGCGAC CTGACGCTAC 180 TATGGβCCGA GTGGCAGGGA CGACGCCCAG AATGGGAGCT GACTGATATG GTGGTβTGGG 240 TGACTββAβC CTCGAGTGGA ATTGGTGAGG AGCTGGCTTA CCAGTTGTCT AAACTAGGAG 300 TTTCTCTTGT GCTGTCAGCC AGAAGAGTGC ATGAGCTGGA AAGGGTGAAA AGAAGATGCC 360 TAGAGAATGG CAATTTAAAA GAAAAAGATA TACTTβTTTT GCCCCTTGAC CTGACCGACA 420 CTGGTTCCCA TGAAGCGGCT ACCAAAGCTβ TTCTCCAGGA GTTTGβTAβA ATCGACATTC 480 TGGTCAACAA TGGTGGAATG TCCCAGCGTT CTCTGTGCAT ββATACCAGC TTGGATGTCT 540 ACAGAAAGCT AATAGAGCTT AACTACTTAG GGACGGTGTC CTTGACAAAA TGTβTTCTGC 600 CTCACATGAT CGAGAGGAAG CAACβAAAβA TTGTTACTGT GAATAGCATC CTGGGTATCA 660 TATCTGTACC TCTTTCCATT GGATACTGTG CTAGCAAGCA TGCTCTCCGG GGTTTTTTTA 720 ATGGCCTTCG AACAGAACTT GCCACATACC CAGGTATAAT AGTTTCTAAC ATTTGCCCAG 780 GAGCTGTGCA ATCAAATATT GTGGAGAATT CCCTAGCTGG AGAAGTCACA AAGACTATAG 840 GCAATAATGG AGACCAGTCC CACAAGATGA CAACCAGTCG TTGTGTGCGG CTGATGTTAA 900 TCAGCATGGC CAATGATTTG AAAGAAGTTT GGATCTCAGA ACAACCTTTC TTGTTAGTAA 960 CATATTTGTG GCAATACATβ CCAACCTGGG CCTGGTGGAT AACCAACAAG ATGββGAAGA 1020 AAAGGATTGA βAACTTTAAβ AGTGGTGTGG ATGCAGACTC TTCTTATTTT AAAATCTTTA 1080 AGACAAAACA TGACTGAAAA GAβCACCTGT ACTTTTCAAG CCACTGGAGG GAGAAATGGA 1140 AAACATGAAA ACAGCAATCT TCTTATGCTT CTGAATAATC AAAGACTAAT TTGTGATTTT 1200 ACTTTTTAAT AGATATGACT TTGCTTCCAA CATGGAATβA AATAAAAAAT AAATAATAAA 1260 AGATTGCCAT GAATCTTGCA AA
Seq ID NO: 598 Protein sequence Protein Accession ft: NP 057113.1
11 21 31 41 51
I I I I I I
MNWELLLWLL VLCALLLLLV QLLRFLRADG DLTLLWAEWQ GRRPEWELTD MWWVTGASS 60 GIGEELAYQL SKLGVSLVLS ARRVHELERV KRRCLENGNL KEKDILVLPL DLTDTGSHEA 120 ATKAVLQEFG RIDILVNNGG MSQRSLCMDT SLDVYRKLIE LNYLβTVSLT KCVLPHMIER 180 KQGKIVTVNS ILGIISVPLS IGYCASKHAL RGFFNGLRTE LATYPβlIVS NICPGPVQSN 240 IVENSLAGEV TKTIGNNGDQ SHKMTTSRCV RLMLISMAND LKEVWISEQP FLLVTYLWQY 300 MPTWAWWITN KMGKKRIENF KSGVDADSSY FKIFKTKHD
Seq ID NO: 599 DNA sequence
Nucleic Acid Accession ft: NM_000793.2
Coding sequence: 401..1222
1 11 21 31 41 51
I I I I I I
GCCTGCAGAG AGAGGCACTT TGCACCACAG ACAGATAGCA AGAAGGβAAA GACAGAGAGT 60 GAGAAAAAAG AGGAGTCAGT CGCTCCTGGG GAAGGGAGAG AGTGAβACTG GGAGAAAGAG 120 AAGCACAGAA AGTGTβTβTA AAACGGAGTA AAGAAAGAAA AAAAAAAAAC TACCCTTAAA 180 GCACATTTAA AAAAAAAAAA CTCTGGCAAT TCAAGAAAGA AACAGGCTAC GTTTAAAGAG 240 CATAGAGACA ATGAAAGGCT AAAGAAAATT TTAAAATCTC TGCCACAGTC TCATAGGTβC 300 TTGGAAATGA AAGTAGAACT GCCTGTCTTT AACCβACTCT GACAGAGAGG GTGAAGGGGA 360 ACCAGAGCGC ACAAGGGAAC TGACTCAGGA GGCAGAGAAG ATGGGCATCC TCAGCGTAGA 420 CTTGCTGATC ACACTGCAAA TTCTGCCAGT TTTTTTCTCC AACTGCCTCT TCCTGGCTCT 480 CTATGACTCG GTCATTCTGC TCAAGCACGT GGTGCTGCTG TTGAGCCGCT CCAAβTCCAC 540 TCGCGGAGAβ TGGCGGCGCA TGCTGACCTC AGAGGGACTG CGCTGCCTCT GGAAGA6CTT 600 CCTCCTCβAT CCCTACAAAC AGGTGAAATT GGGTGAGGAT GCCCCCAATT CCAGTβTGGT 660 GCATGTCTCC AGTACAGAAG GAGGTGACAA CAGTGGCAAT GGTACCCAGG AGAAGATAβC 720 T6AGGGAGCC ACATGCCACC TTCTTGACTT TGCCAGCCCT GAGGGCCCAC TAGTGGTCAA 780 CTTTGGCTCA GCCACTTGAC CTCCTTTCAC GAGCCAGCTG CCAGCCTTCC GCAAACTGGT 840 GGAAGAGTTC TCCTCAGTGG CTGACTTCCT GCTGGTCTAC ATTGATGAGG CTCATCCATC 900 AGATGGCTGG GCGATACCGG GGβACTCCTC TTTGTCTTTT GAGGTGAAGA AGCACCAGAA 960 CCAGGAAGAT CGATGTGCAG CAGCCCAβCA GCTTCTGGAG CGTTTCTCCT TGCCCCCCCA 1020 GTGCCGAGTT GTGGCTGACC GCATGGACAA TAACGCCAAC ATAGCTTACG GGGTAβCCTT 1080 TβAACGTGTG TGCATTGTGC AGAGACAGAA AATTGCTTAT CTGGGAGGAA AGGβCCCCTT 1140 CTCCTACAAC CTTCAAβAAG TCCGGCATTG GCTGGAGAAG AATTTCAGCA AGAGATGAAA 1200 GAAAACTAGA TTAGCTGGTT AAAGGTATGA TTATAAGAGA GCTTATTGTT TTAAAAAGTT 1260 ATATAAAGGC AAGGAAATTA AGAACTGAAT CCATATTTCA ACAGAβCCCT ATTGGCTTAC 1320 TGAAAGACAG GAGTTTATCT ATCGGAAGAA CATGAATCTC TAACAβCTCC ATACTTCTTT 1380 CACTACTCAA ATGGCATTGG GCTGAGTAAG TAACCATATC ACCTCTCTTC TTAGTAAAAA 1440 GCCCTATGTG AAAAGATCCC AAGATGGAGA GGAAGAAACG CTAATTCAGC ATGTGTTCAT 1500 TCTGCATTGA GAAGGAACTG ATACATCTGA TGCATGCTTT GAGACCAGAA GAAAAGACTT 1560 ACCTGAATAA TTACTACATT AGGGAAGCTA CTGTCTACGT TAAGATAAAG GGTATTGCCT 1620 TGGCTCTATT TGGCATGGAT GGAGCCCAGT TGGAAAATTC CCAAATATTA CAACAAGTCC 1680 TTGAACCCAG GCCATGTβGT TAGACGTTGG TGTTAAGGTT AGACCTTATG TTAGAGTCAT 1740 TTCTGATGTT CCAGCTTCTA GCCATGTAGT GCTCTCAGTC TTCATACCCC AGAAATTATT 1800 GGTATATTTG TAGATACCGA GAATGATCCC TCAGTCTGAG AGGTTAβAAT GATCATCTGT 1860 AATCTGAβGG TTAATTTCTA GGCAGGTGGA GAGAGTCGTA AAAAAGAAAT GAAATTGACA 1920 AGCTAGGAAA GAGGAGGCAG AAAGATTTGG AAAATTCACA GAGTTTCACC CTTAAGCTGT 1980 AGAGAGTGGG TCACATTTGT TAGCCACGGA AACATAGAAA CATACACAAG GCCAGAAAAA 2040 GAAGAAGGAG CTCAACTAAA AGTGGCATAG AGAATACACA TATAAAAACA ATATATTTGT 2100 CATATGCTCC TAGAGAGGAG AAAGGGGTGA TTGAAAGAAA AAAAAATACT TAAATATTTG 2160 TAATTGTGAG GGGTTTCTTT TGGAAATAAT TACTTTTGAA CCATGTATGT GGTATGTATA 2220 TTTTCAGTGG GTTAATTATA CCCCATGATA CCTATTAAAG GAAAACCAGT GGGTCTGGTG 2280 GTGCTGGTCT TTTCCTCCCC ATTCCTACAA TTTCTATGTG GCCCAAGTCA TTCCTAATCT 2340 TGGTCTCTAT AGCAGTGTTC TCTCTGAATG CTGAGCTGAA GAAATTATAC GTACATACAC 2400 ACATACATAC ATACATACAA ATATATGTAT ATATATTCTC AGCTGCTβCG GGAGGTAGGT 2460 ACCATGGCCA TTCAGCACAG CCTTGATTTC CTCCCAAAGT AGGTβAβCTA TAGTGAAGAA 2520 TAGGTGCAAA CAAACAAGCT TACTTCCATT GCAAAATAGA AGAAβAββAA GTTAGAGATA 2580 ATTCTGATCA ATCATTTTGG AGGCTTTGTT ATAAGβCAAC CCCCG6TATA TCATGGAATT 2640 TCCATTGACA TTTGAATTTG GACTTGGATC TTCCCTTGGT CCCATTAGCT GAGGTTTAGT 2700 AATCTAAAGT CCCTATAGTA TATGATTATA ATGCTATTTT AAAAAATATA TATATAAAAT 2760 ATTTTTTTCT TTTTAAAATA GACACTATAβ TTTTACCCAT AAGTAATATT TAAAGATTAT 2820 AGCTCCCAAA AGAATβGACC AACCACTTTC GTATCATAAT TTCTTTTTGG TAAATATGAG 2880 ACTATTATGA AATCATAGTA TATGATTGTA TTTAAAGGTA CAATCAAAGG ATCTTTTGTC 2940 CATTCCATTA ATAACTGAAT AAAAAATAAA TAAAATGGAT AGAAAAAAAC TAAAGTTβAA 3000 AATACATTCT TAAACTAGTT GTCTGAAATG AGAAAAGAβT GAGAACTAGG TGTβCAAβAA 3060 CCAAACGTAT TTTATTTTAT TTTTTAAATG GGAGCAACAT ATCAGTCGTG TCACCAGCTG 3120 GTATATTGTG TAAATATTAA AGCTCCATTG GGACTGATTT TTCATGGCAA CATCAGCTTT 3180 CTAATGTTCT AAATTCTATA AAAACCACCC ACAAAGAAAC AAAGCAAATT TCATTATCTA 3240 ATGAGTTGCT GGAAAATCAT ATTGAGAATA ATTATTTCAG ATTCCTCAGT TGTTAACTTC 3300
TACATTCAAβ GGCTTATCTC TGCCCCCATT GATTTTTAAC CTCAAAATGG TGTGAGATTT 3360
ACTGTGGAAC CCTAAAGCAG TAAAATAAAA AACCTGGTTG CAGCACATTC ACACTGTTGT 3420
CCTTAAAATT CCCCTTTTTT CTCTATGTAC GATAAAGTAA CAGTATGTCA GATAAGCCGG 3480
TGGGGGGATG AGATTAGGCT GAGGCAGTGC TAGTCAACTG GGGGAAAAGG ATGATβGAAA 3540
AATCACCCAG TTGTGCTATA TTTTTAAAGA AGGAGGTCGT TTATGTGTGC AGACAATTCT 3600
CCCTGAGGTT AGCCCAATGG AGAAATGAAG CAGAGGAAGG AAACATAGAA AGACATβGGC 3660
TATCAGβGAG GAAGATGTTC AATAGAACAT GCAAGAATTT CTGGAAGAAA GGCTGTGGAA 3720
GGGCCAATGG AGAAAATGAA TGGACAAAGC TCAGGAATCC CTACβCTATG TAGAATGTTC 3780
TTGGTGTTAT CAGGGTTAAG CCCTGTAATT ATGTAACCTA TTTATCGCAA CATGAATTTT 3840
TATGATTTCT TGTGATβTAT TCTTTTATGA AATTAACAAG AACTCATTAT TTTGAGGTAG 3900
AGGAAAATCA ATGCTTTATC TGATATGCTG AGAAATTATT AGATTGCCAA TACTCATGTG 3960
CGTTTCATGT GTTTTATAAG GTTTGTTCCT TTGAAGAATT GTAGTTCTTA GTCCCACAGG 4020
GAAATGTGTA TCTATTTATA TATCATAGTA TAAATCTATG ATATATTTAT ATCATATATA 4080
AAAGTCTGAG TTCTCTTTCT TAGTCCCTAA TCATGTTTCT CCCATAGGCT GTGTTTACAT 4140
GβAGCTATCG GTTTAGCCTT TTAAGCTTCA TTAGCTTGTC TATTATTGAA ATAGTTTCCA 4200
AGAAATTTTA GATATTATCA TAACATCTGG GTCTACTCAA ACACTTATTG TTTGAAAGAC 4260
TTATGTCTTG GACCTATCAA AAACTGACTT TATTTATTGC TTAGTGAAAA TACTAGTGGG 4320
ATCAACAATG ATTTTCTTGA ATGGGCATGA ATGGAGATGC CCGCACAGTA ATGTAGAAAT 4380
GTTTCATACA GCTATTAAAA TGTAACTGAC CTCCTTAGAG GCAGATTAGT AACTGTTCCT 4440
ACTTTGTATA GCTAAGTGAC AGTCACTTAA CTTACATGAC TTTCTTTTTT CACATTGGGT 4500
CTCTGGTCCT GTGTCTTCAC CTCATTTATA GCACGTCTCC TTGATTTTTG GTAβTATCAA 4560
CTTCCCAGTG ATCTGTTCAG TTAAGTTCTT CTCCCGTTAA CCAGGAAβTβ CTTATTCTCT 4620
CATCACAGTG GGAAGAATAG CCTATTGTCT TTCATTTTGC CTGAGTGTAT TTTACTATTT 4680 βGGCTCTCAA ATAAAAATTA TβAAATATGG TGAGGTCACA TGTTGGTGCT GCCTTGCTGC 4740
ATAAAATTCT AGGAGGGCAG GTTAGGAGAC AGTTATGTAT GGCCTTTCGG GAAAATTCAA 4800
AGGGTGGβAT TACAAGGGTβ TTCCTCAGGC ATGCCCCTAT GGGCCCTATG TGβAAβCAAβ 4860
AAGAATTGAC TGATTTACAG GACTTCTCTT TATGTCAATC TTAAGAGGAT GβATβAATCT 4920
GGACATTTGT TCCACCCGAC CTCTGACTGA TGGTTTGGAA AATAACTTTA ATTAGGATCA 4980
TATGACCATT GAAAAAGGAA AAATGTAGAC TCTGACTTCC GTCCCACTGA AGGATTAATG 5040
AAAACCTTTA CTAGCATTTA GAβCTTTTCA GAACATCCCC ACTβTCATβT GTCTCAGCAG 5100
TGGAGACTGC AAGTAAβGCT TTTAATTTTA GGAGGTTTTT TTTTTTTTTT TTTTTTCCCC 5160
TAAATGGTAT GGCCAAAAGT CAGAGTTAAA ATATATATAG TTAGATTCCA ACTTCCTCCT 5220
TCACTCTAAA AATAGAATCC AAACCCACTC TTCATATATG CTTCCAGAAT GGββCTTAAG 5280
TACCAATCTC TGCTTTGCAA TGGGCACAAT CTTGGTCATG TCCTGAββCT CTCTAAGAAA 5340
AGAGAGGATC TAGGATGGGA GAGCTAβAAA GTTGCTAACT GGGAAGAACA AGGCCCTGAG 5400
GGGTTGGTCT ACCAATCTGG GAAGATTTGA AAACAAACTT CTCGCAACTG AAGGAAGGCT 5460
GAAGGCTGCT GCAAGTCATT GAGTGACTTT AGGATGAGCA AAACATTGGG CCACTTCCTA 5520
ATGCCCTATG TGTATAGTAC CAGAAGCAAG GTCTCAGACT TAACAGACCC AβCTCTGTTC 5580
CAAGGTGAGT CTGAACCAAT AGAAAGCAAA CATGTGCAGA TATCCAAACA AGACTβCTCA 5640
TGCAAGTCGG GGCTGGCTAC CCGTCTTAGG CAGCAACAGC AGAGCTCCAG GGAGCTTATT 5700
CAATATTTAC TGAGACTTCG AAGACCCAβC AβATGTTTAA TGAAGTCACT ATTTTGGCTC 5760
AAACCCTCCA CTTCTCCCCC TCCCCTCAAA AAGCCAACAG GTAAACACAT AAATGAAAGA 5820
AACCCACAGA AGGGGATGGG AAATAAAGAA AATTCTCTCA AGACTTCTCC AGGCCCATGT 5880
CACTGGTCAG CGTGβTTTTT ATGTGTATTA GGATTGβββG ATGTGAAGAA ATAAGTATCC 5940
AGTACTTTAT AACCAAAGCA ATTAAATGAT ATTGGGGTAG GGAATCTTGG CCAGTTTTGT 6000
TTAGTTTTGC CATCACATTG TCACCCAGAC CTCACCTAGC CCCAAGTAAT CGGGCGCCCC 6060
GAAGAGGGAG ACAGAGATGT GCCAGAGTTβ ACCCAβTGTG CGGATGATAA CTACTGACGA 6120
AAβAβTCATC GACCTCAGTT AGTGGTTGβA TβTAβTCACA TTAGTTTGCC TCTCCCCATC 6180
TTTGTCTCCC TGGCAAGGAG AATATGCG6G ACATGATGCT AAGAGCCCTG GGTAAATGTG 6240
GTGAGAATGC ACβCGTGCAT ATGCTACACA TATGTGCTTC TCAGTTGCAG AAAATGAACT 6300
GCTTTGGGAG ATTATCAGTA βAAAGAGTGT TATCATATTG GTGCTGAGTG CTATGTGTGC 6360
TTATACAATT TGTTCTTGTA TTTTAATAAA CTTTGAATAA AAGAATAAAA AAAAAAAAAA 6420
AAAAAAAAA
Seq ID NO: 600 Protein sequence Protein Accession ft: NP 000784.2
1 11 21 31 41 51
I I I I I I
MGILSVDLLI TLQILPVFFS NCLFLALYDS VILLKH LL LSRSKSTRβE WRRMLTSEGL 60
RCVWKSFLLD AYKQVKLGED APNSS HVS STEGGDNSGN GTQEKIAEGA TCHLLDFASP 120
ERPLWNFGS ATUPPFTSQL PAFRKLVEEF SSVADFLLVY IDEAHPSDGW AIPGDSSLSF 180
EVKKHQNQED RCAAAQQLLE RFSLPPQCRV VADRMDNNAN IAYGVAFERV CIVQRQKIAY 240 LGGKGPFSYN LQEVRHWLEK NFSKRUKKTR LAG
Seq ID NO: 601 DNA sequence
Nucleic Acid Accession ft: NM_005233.1
Coding sequence: 101..3052
1 11 21 31 41 51 1 1 I 1 I 1 | 1 | 1 | 1 CCATGGATGG TAACTTCTCC AGCAATCAGA GCGCTCCCCC TCACATCAGT GGCATGCTTC 60
ATGGAGATAT GCTCCTCTCA CTGCCCTCTG CACCAGCAAC ATGGATTGTC AGCTCTCCAT 120
CCTCCTCCTT CTCAGCTGCT CTGTTCTCβA CAGCTTCGGG GAACTGATTC CGCAGCCTTC 180
CAATCAAGTC AATCTACTGG ATTCAAAAAC AATTCAAGGG GAGCTGGGCT GGATCTCTTA 240
TCCATCACAT GGGTGGGAAG AGATCAGTGG TGTGGATGAA CATTACACAC CCATCAGGAC 300
TTACCAGGTG TGCAATGTCA TGGACCACAβ TCAAAACAAT TGβCTGAGAA CAAACTGGGT 360
CCCCAGGAAC TCAGCTCAGA AGATTTATGT GGAGCTCAAG TTCACTCTAC GAGACTGCAA 420
TAGCATTCCA TTGGTTTTAG GAACTTGCAA GGAGACATTC AACCTGTACT ACATGGAGTC 480
TGATGATGAT CATGGGβTGA AATTTCGAβA GCATCAGTTT ACAAAGATTG ACACCATTCC 540
AGCTGATGAA AGTTTCACTC AAATGGATCT TGGGGACCGT ATTCTGAAGC TCAACACTGA 600
GATTAGAOAA GTAGGTCCTG TCAACAAGAA GGGATTTTAT TTGGCATTTC AAGATGTTGG 660
TGCTTGTGTT GCCTTGGTGT CTβTGAGAGT ATACTTCAAA AAGTGCCCAT TTACAGTGAA 720 GAATCTGGCT ATGTTTCCAG ACACGGTACC CATGβACTCC CAGTCCCTGG TGGAGGTTAG 780
AGGGTCTTGT GTCAACAATT CTAAGGAGGA AGATCCTCCA AGGATGTACT βCAβTACAβA 840
AGGCGAATGG CTTGTACCCA TTGGCAAGTG TTCCTGCAAT GCTGGCTATG AAGAAAGAGG 900
TTTTATGTGC CAAGCTTGTC GACCAGGTTT CTACAAGGCA TTGGATGGTA ATATGAAGTG 960
TGCTAAGTGC CCGCCTCACA GTTCTACTCA GGAAGATGGT TCAATGAACT βCACGTGTGA 1020
GAATAATTAC TTCCGGGCAG ACAAAGACCC TCCATCCATG GCTTGTACCC GACCTCCATC 1080
TTCACCAAβA AATGTTATCT CTAATATAAA CGAGACCTCA GTTATCCTGG ACTGGAβTTβ 1140
GCCCCTGGAC ACAGGAGGCC GGAAAGATGT TACCTTCAAC ATCATATGTA AAAAATGTGG 1200
GTβGAATATA AAACAGTGTG AGCCATGCAG CCCAAATGTC CGCTTCCTCC CTCGACAGTT 1260
TGGACTCACC AACACCACGG TGACAβTGAC AGACCTTCTG GCACATACTA ACTACACCTT 1320
TGAGATTGAT GCCGTTAATG GGGTβTCAGA GCTGAGCTCC CCACCAAGAC AGTTTGCTGC 1380
GGTCAGCATC ACAACTAATC AGβCTGCTCC ATCACCTGTC CTGACGATTA AGAAAGATCG 1440
GACCTCCAGA AATAGCATCT CTTTGTCCTG GCAAGAACCT GAACATCCTA ATGGGATCAT 1500
ATTGGACTAC GAGβTCAAAT ACTATβAAAA GCAGGAACAA GAAACAAGTT ATACCATTCT 1560
GAGGGCAAGA GGCACAAATG TTACCATCAβ TAGCCTCAAG CCTβACACTA TATACCTATT 1620
CCAAATCCGA GCCCβAACAG CCGCTGGATA TGGGACGAAC AGCCGCAAGT TTGAGTTTβA 1680
AACTAGTCCA βACTCTTTCT CCATCTCTGG TGAAAGTAGC CAAGTGGTCA TGATCGCCAT 1740
TTCAGCGGCA GTAGCAATTA TTCTCCTCAC TGTTGTCATC TATGTTTTGA TTGGGAGGTT 1800
CTGTGGCTAT AAGTCAAAAC ATGGGGCAGA TGAAAAAAGA CTTCATTTTG GCAATGGGCA 1860
TTTAAAACTT CCAGGTCTCA GGACTTATGT TGACCCACAT ACATATGAAG ACCCTACCCA 1920
AGCTGTTCAT GA6TTTGCCA AββAATTGGA TGCCACCAAC ATATCCATTG ATAAAGTTGT 1980
TGβAβCAGGT GAATTTGGAG AGGTGTGCAG TGGTCGCTTA AAACTTCCTT CAAAAAAAGA 2040
GATTTCAGTG GCCATTAAAA CCCTGAAAGT TGGCTACACA GAAAAGCA6A GGAGAGACTT 2100
CCTGGGAGAA GCAAGCATTA TGGGACAGTT TGACCACCCC AATATCATTC GACTGGAAGG 2160
AGTTGTTACC AAAAGTAAGC CAGTTATGAT TGTCACAβAA TACATGGAGA ATGGTTCCTT 2220
GGATAGTTTC CTACGTAAAC ACGATGCCCA GTTTACTGTC ATTCAGCTAG TGGGGATGCT 2280
TCGAGGGATA GCATCTGGCA TGAAβTACCT GTCAGACATG GGCTATGTTC ACCGAGACCT 2340
CGCTβCTCGG AACATCTTGA TCAACAβTAA CTTGGTGTGT AAGGTTTCTG ATTTCGGACT 2400
TTCGCGTGTC CTββAGGATG ACCCAGAAGC TGCTTATACA ACAAGAGGAG GβAAβATCCC 2460
AATCAβGTGG ACATCACCAG AAGCTATAGC CTACCGCAAG TTCACGTCAG CCAβCGATGT 2520
ATGGAGTTAT GGGATTGTTC TCTGGGAGGT GATGTCTTAT ββAβAβAβAC CATACTGGGA 2580
GATGTCCAAT CAGGATGTAA TTAAAGCTGT AGATβAGGβC TATCGACTGC CACCCCCCAT 2640
GGACTGCCCA GCTGCCTTGT ATCAGCTGAT GCTGGACTGC TGGCAGAAAG ACAGGAACAA 2700
CAGACCCAAG TTTβAGCAGA TTGTTAβTAT TCTGGACAAG CTTATCCGGA ATCCCGGCAβ 2760
CCTGAAGATC ATCACCAGTG CAGCCGCAAG GCCATCAAAC CTTCTTCTGβ ACCAAAGCAA 2820
TGTGGATATC TCTACCTTCC GCACAACAGG TGACTGGCTT AATGGTGTCC GGACAGCACA 2880
CTGCAAGGAA ATCTTCACGG GCGTGGAGTA CAGTTCTTGT GACACAATAβ CCAAβATTTC 2940
CACAGATGAC ATGAAAAAGG TTGGTGTCAC CGTGGTTGGG CCACAβAAβA AβATCATCAG 3000
TAGCATTAAA GCTCTAGAAA CGCAATCAAA GAATGGCCCA GTTCCCGTβT AAAGCACGAC 3060
GGAAGTβCTT CTGGACGGAA GTGGTGGCTG TGGAAGGCGT CAACTCATCC TGCAGACAβA 3120
CAATAATTCT βGAGATACTG GTGGAAGTT
Seq ID NO: 602 Protein sequence Protein Accession ft: NP 005224.1
11 21 31 41 51
I I I I I
MDCQLSILLL LSCSVLDSFG ELIPQPSNEV NLLDSKTIQG ELGWISYPSH GWEEISGVDE 60 HYTPIRTYQV CNVMDHSQNN WLRTNWVPRN SAQKIYVELK FTLRDCNSIP LVLGTCKETF 120 NLYYMESDDD HGVKFREHQF TKIDTIAADE SFTQMDLGDR ILKLNTEIRE VGPVNKKGFY 180 LAFQDVGACV ALVSVRVYFK KCPFTVKNLA MFPDTVPMDS QSLVEVRGSC VNNSKEEDPP 240 RMYCSTEGEW LVPIGKCSCN AGYEERGFMC QACRPGFYKA LDGNMKCAKC PPHSSTQEDG 300 SMNCRCENNY FRADKDPPSM ACTRPPSSPR NVISNINETS VILDWSWPLD TGGRKDVTFN 360 IICKKCeWNI KQCEPCSPNV RFLPRQFGLT NTTVTVTDLL AHTNYTFEID AVNGVSELSS 420 PPRQFAAVSI TTNQAAPSPV LTIKKDRTSR NSISLSWQEP EHPNGIILDY EVKYYEKQEQ 480 ETSYTILRAR GTNVTISSLK PDTIYVFQIR ARTAAGYGTN SRKFEFETSP DSFSISGESS 540 QWMIAISAA VAIILLTWI YVLIGRFCGY KSKHGADEKR LHFGNGHLKL PGLRTYVDPH 600 TYEDPTQAVH EFAKELDATN ISIDK GAG EFGEVCSGRL KLPSKKEISV AIKTLKVGYT 660 EKQRRDFLGE ASIMGQFDHP NIIRLEGWT KSKPVMIVTE YMENGSLDSF LRKHDAQFTV 720 IQLVGMLRGI ASGMKYLSDM GYVHRDLAAR NILINSNLVC KVSDFGLSRV LEDDPEAAYT 780 TRGGKIPIRW TSPEAIAYRK FTSASDVWSY GIVLWEVMSY GERPYWEMSN QDVIKAVDEG 840 YRLPPPMDCP AALYQLMLDC WQKDRNNRPK FEQIVSILDK LIRNPGSLKI ITSAAARPSN 900 LLLDQSNVDI STFRTTGDWL NGVRTAHCKE IFTGVEYSSC DTIAKISTDD MKKVGVTWG 960 PQKKIISSIK ALETQSKNGP VPV
Seq ID NO: 603 DNA sequence
Nucleic Acid Accession ft: NM_005727.1
Coding sequence: 122..847
11 21 31 41
GCCAGGCGTC CCTCTGCCTG CCCACTCAGT GGCAACACCC GGGAGCTGTT TTGTCCTTTG 60
TGGAGCCTCA GCAGTTCCCT CTTTCAGAAC TCACTGCCAA GAβCCCTβAA CAGGAGCCAC 120
CATGCAGTGC TTCAGCTTCA TTAAGACCAT GATGATCCTC TTCAATTTGC TCATCTTTCT 180
GTGTGGTGCA GCCCTGTTGG CAGTβGGCAT CTGGGTGTCA ATCGATGGGβ CATCCTTTCT 240
GAAGATCTTC GGGCCACTGT CGTCCAGTGC CATGCAGTTT GTCAACGTGG GCTACTTCCT 300
CATCGCAGCC GGCGTTGTGG TCTTTGCTCT TGGTTTCCTG GβCTβCTATβ GTGCTAAGAC 360
TGAGAGCAAG TGTGCCCTCG TGACGTTCTT CTTCATCCTC CTCCTCATCT TCATTβCTβA 420
GβTTGCAGCT GCTβTGGTCG CCTTGGTGTA CACCACAATG GCTGAGCACT TCCTGACGTT 480
GCTGGTAGTG CCTGCCATCA AGAAAGATTA TGGTTCCCAG GAAGACTTCA CTCAAGTGTG 540
GAACACCACC ATGAAAGGGC TCAACTGCTG TGGCTTCACC AACTATACGG ATTTTGAGGA 600
CTCACCCTAC TTCAAAGAGA ACAGTGCCTT TCCCCCATTC TGTTβCAATG ACAACGTCAC 660
CAACACAGCC AATGAAACCT GCACCAAGCA AAAGGCTCAC GACCAAAAAG TAGAGGGTTG 720
CTTCAATCAG CTTTTGTATG ACATCCGAAC TAATGCAGTC ACCGTGGGTG GTGTGGCAGC 780 TGGAATTGGG GGCCTCGAGC TGGCTGCCAT GATTGTGTCC ATGTATCTGT ACTGCAATCT 840 ACAATAAGTC CACTTCTGCC TCTGCCACTA CTGCTGCCAC ATGGGAACTG TGAAGAGGCA 900 CCCTGGCAAG CAGCAGTβAT TGGG6GAGGG GACAGGATCT AACAATGTCA CTTGGβCCAG 960 AATGGACCTG CCCTTTCTβC TCCAGACTTG GGGCTAGATA GGGACCACTC CTTTTAGβCG 1020 ATGCCTGACT TTCCTTCCAT TGGTGGGTGG ATGβGTGGGG GGCATTCCAG AGCCTCTAAG 1080 GTAGCCAGTT CTGTTGCCCA TTCCCCCAGT CTATTAAACC CTTGATATGC CCCCTAGGCC 1140 TAGTβGTGAT CCCAGTGCTC TACTGβGGGA TGAGAGAAAG GCATTTTATA GCCTGββCAT 1200 AAGTGAAATC AGCAGAGCCT CTGGGTGGAT GTGTAGAAGG CACTTCAAAA TGCATAAACC 1260 TGTTACAATG TTAAAAAA
Seq ID NO : 604 Protein sequence Protein Accession ff: NP 005718.1
1 11 21 31 41 51
I I I I I I
MQCFSFIKTM MILFNLLIFL CGAALLAVGI WVSIDGASFL KIFGPLSSSA MQFVNVGYFL 60
IAAGVWFAL GFLGCYGAKT ESKCALVTFF FILLLIFIAE VAAAWALVY TTMAEHFLTL 120
LWPAIKKDY GSQEDFTQVW NTTMKGLKCC GFTNYTDFED SPYFKENSAF PPFCCNDNVT 180
NTANETCTEQ KAHDQKVEGC FNQLLYDIRT NAVTVGGVAA GIGGLELAAM IVSMYLYCNL 240 Q
Seq ID NO: 605 DNA sequence
Nucleic Acid Accession #: NM_000729.2
Coding sequence:
1 11 21 31 41 51 1 1 | 1 I 1 1 1 | 1
GGCTCAGCTG CCGGGCTGCT CCGGTTGGAA A∞CCAAGCC AGCTGCCGTC CTAATCCAAA 60
AGCCATGAAC AGCGGCGTGT GCCTGTGCGT GCTGATGGCβ GTACTGGCββ CTGGCGCCCT 120
GACGCAGCCG GTGCCTCCCG CAGATCCCGC GGGCTCCGββ CTGCAβCGGβ CAGAGGAGGC 180
GCCCCGTAGG CAGCTGAGGG TATCGCAGAG AACGβATGGC GAGTCCCGAβ CGCACCTGGG 240
CGCCCTGCTG GCAAGATACA TCCAGCAGGC CCGGAAAGCT CCTTCTGGAC GAATGTCCAT 300
CGTTAAGAAC CTGCAGAACC TGGACCCCAG CCACA6GATA AGTGACCGGG ACTACATGGG 360
CTGβATβGAT TTTGGCCGTC GCAGTβCCGA GGAGTATGAG TACCCCTCCT AGAGGACCCA 420
GCCGCCATCA GCCCAACGGA AGCAACCTCC CAACCCAGAG GAGGCAGAAT AAGACAACAA 480
TCACACTCAT AACTCATTGT CTGTGGAGTT TGACATTβAA TGTATCTATT TATTAAGTTC 540
TCAATGTGAA AATTGTGTCT GTAAGATTGT CCAGTGCAAC CACACACβCT CACCAGAAGT 600
TGTGCAAACT GAAGACAAAA CTGTTTTCTT CATCTGTGAC TCCTGTTCTG AAAATGTTGT 660
TATβCTATTA AAGTGATTTC ATTCTGCC
Seq ID NO: 606 Prote:in sequence
Protein Accession #: NP 000720.1 1 11 21 31 41 51 i i i i i i
MNSGVCLCVL MAVLAAGALT QPVPPADPAG SGLQRAEEAP RRQLRVSQRT DGESRAHLβA LLARYIQQAR KAPSβRMSIV KNLQNLDPSH RISDRDYMGW MDFGRRSAEE YEYPS
Seq ID NO : 607 DNA sequence Nucleic Acid Accession if : NM_001423 .1
Coding sequence : 219 . . 692
1 11 21 31 41 51
I
AGCACTCTCC A IGCCTCTCAC C IGCAAAATTA C IACACCCCAG T IACACCAGCA G IAGGAAACTT 60 ATAACCTCGG GAGGCGGβTC CTTCCCCTCA GTGCGGTCAC ATACTTCCAG AAGAGCGGAC 120 CAGGGCTGCT GCCAGCACCT GCCACTCAGA GCGCCTCTGT CGCTGGGACC CTTCAGAACT 180 CTCTTTGCTC ACAAGTTACC AAAAAAAAAA GAGCCAACAT GTTGGTATTG CTGGCTGGTA 240 TCTTTGTGGT CCACATCGCT ACTGTTATTA TGCTATTTGT TAGCACCATT GCCAATGTCT 300 GGTTGGTTTC CAATACGGTA βATGCATCAG TAGGTCTTTG GAAAAACTGT ACCAACATTA 360 GCTGCAGTGA CAGCCTGTCA TATGCCAGTG AAGATβCCCT CAAGACAGTG CAGGCCTTCA 420 TGATTCTCTC TATCATCTTC TGTGTCATTG CCCTCCTGGT CTTCGTGTTC CAGCTCTTCA 480 CCATGGAGAA GGGAAACCGG TTCTTCCTCT CAGGGGCCAC CACACTβGTG TGCTβGCTGT 540 GCATTCTTGT GGGGGTβTCC ATCTACACTA GTCATTATGC GAATCGTGAT GGAACCCAGT 600 ATCACCACGG CTATTCCTAC ATCCTGGGCT GGATCTGCTT CTGCTTCAGC TTCATCATCG 660 GCGTTCTCTA TCTGGTCCTG AGAAAGAAAT AAGGCCGGAC GAGTTCATGG GGATCTGGβG 720 GGTGGGGAGG AGGAAGCCGT TGAATCTGGG AGGGAAGTGG AGGTTGCTGT ACAGβAAAAA 780 CCGAGATAGG GGAGGGGGGA GGGGGAAGCA AAGGGGGGAG GTCAAATCCC AAACCATTAC 840 TGAGGGGATT CTCTACTGCC AAGCCCCTβC CCTGGGGAGA AAGTAGTTGG CTAGTACTTT 900 GATGCTCCCT TGATGGGGTC CAGAGAβCCT CCCTGCAGCC ACCAGACTTG GCCTCCAGCT 960 GTTCTTAGTG ACACACACTG TCTGGGGCCC CATCACCT6C CACAACACCA GCCCCACTTC 1020 TGGGTCATGC ACTGAGGTCC ACAGACCTAC TβCACTCAGT TAAAATAGCG GTACAAGTTC 1080 TGGCAAGAGC AGATACTGTC TTTGTGCTGA ATACGCTAAβ CCTGGAAGCC ATCCTGCCCT 1140 TCTGACCCAA AGCAAAACAT CACATTCCAG TCTβAAβTβC CTACTGGGGG GCTTTGGCCT 1200 GTGAGCCATT GTCCCTCTTT GGAACAGATA TTTAGCTCTG TGGAATTCAG TGACAAAATG 1260 GGAGGAGβAA AGAGACTTTG TAAGGTCATG CTGGTGG6TT AGCTAAACCA AGAAGGAGAC 1320 CTTTTCACAA TGGAAAACCT GGGGGATGGT CAβAGCCCAG TCGAGACCTC ACACACGGCT 1380 GTCCCTCATG GAGACCTCAT GCCATGGTCT TTGCTAGGCC TCTTβCTβAA AGCCAAGGCA 1440 GCTCTTCTGG AGTTTCTCTA AAGTCACTAG TGAACAATTC βGTGGTAAAA GTACCACACA 1500 AACTATGGGA TCCAAGGGGC AGTCTTGCAA CAGTGCCATG TTAGGGTTAT GTTTTTAGGA 1560 TTCCCCTCAA TGCAGTCAGT GTTTCTTTTA AGTATACAAC AGGAGAβAGA TGGACATGGC 1620 TCATTGTAGC ACAATCCTAT TACTCTTCCT CTAACATTTT TGAGGAAGTT TTGTCTAATT 1680 ATCAATATTG AGGATCAGGG CTCCTAGGCT CAGTGGTAGC TCTGGCTTAG ACACCACCTG 1740 GAGTGATCAC CTCTTGGGGA CCCTGCCTAT CCCACTTCAC AGGTGAGGCA TGGCAATTCT 1800 GGAAGCTGAT TAAAACACAC ATAAACCAAA ACCAAACAAC AGGCCCTTGG GTGAAAGGTG 1860 CTATATAATT GTGAACTATT AAGCCTACCG TATTTCAGCC ATGATAAGAA CAGAGTGCCT 1920 GCATTCCCAG GAAAATACβA AAATCCCATG AGATAAATAA AAATATAGGT GATGGGCAβA 1980 TCTTTTCTTT AAAATAAAAA AGCAAAAACT CTTGTGGTAC CTAGTCAGAT GβTAGACβAG 2040 CTGTCTGCTG CCGCAGGAGC ACCTCTATAC AββACTTAGA AGTAGTATGT TATTCCTGβT 2100 TAAGCAGGCA TTβCTTTGCC CTGGAGCAGC TATTTTAAGC CATCTCAGAT TCTβTCTAAA 2160 GGGGTTTTTT GGGAAGACβT TTTCTTTATC GCCCTGAGAA GATCTACCCC AβββAβAATC 2220 TGAGACATCT TGCCTACTTT TCTTTATTAG CTTTCTCCTC ATCCATTTCT TTTATACCTT 2280 TCCTTTTTGG GGAGTTGTTA TGCCATGATT TTTGGTATTT ATGTAAAAGG ATTATTACTA 2340 ATTCTATTTC TCTATGTTTA TTCTAGTTAA GGAAATGTTG AGGGCAAGCC ACCAAATTAC 2400 CTAGGCTGAG GTTAGAGAGA TTGβCCAGCA AAAACTGTββ GAAGATGAAC TTTGTCATTA 2460 TGATTTCATT ATCACATGAT TATAGAAGGC TGTCTTAGTG CAAAAAACAT ACTTACATTT 2520 CAGACATATC CAAAGGGAAT ACTCACATTT TGTTAAGAAβ TTGAACTATG ACTGGAGTAA 2580 ACCATGTATT CCCTTATCTT TTACTTTTTT TCTGTGACAT TTATGTCTCA TGTAATTTGC 2640 ATTACTCTGG TGGATTGTTC TAGTACTGTA TTGGGCTTCT TCGTTAATAG ATTATTTCAT 2700 ATACTATAAT TGTAAATATT TTGATACAAA TGTTTATAAC TCTAGGGATA TAAAAACAGA 2760 TTCTGATTCC CTTCAAAAAA AAAAAA
Seq ID NO: 608 Protein sequence Protein Accession ft: NP 001414.1
1 11 21 31 41 51
I I I I I I
MLVLLAGIFV VHIATVIMLF VSTIANVWLV SNTVDASVGL WKNCTNISCS DSLSYASEDA 60 LKTVQAFMIL SIIFCVIALL VFVFQLFTME KGNRFFLSβA TTLVCWLCIL VβVSIYTSHY 120
ANRDGTQYHH GYSYILGWIC FCFSFIIGVL YLVLRKK
Seq ID NO : 609 DNA sequence
Nucleic Acid Accession ft : NM_004961.2
Coding sequence : 55 . .1575
21 31 41 51
I I I I I I
GCCAGAGCGT GAGCCGC6AC CTCCGCGCAG GTGGTCGCGC CGGTCTCCGC GGAAATGTTG 60
TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAβTCβAG GGTCGAGGβA 120
CCTCAGACTG AATCAAAGAA TGAAGCCTCT TCCCGTβATG TTGTCTATGG CCCCCAGCCC 180
CAGCCTCTGG AAAATCAGCT CCTCTCTGAG GAAACAAAGT CAACTGAGAC TGAGACTGβG 240
AβCAGAGTTG GCAAACTGCC AGAAGCCTCT CGCATCCTGA ACACTATCCT GAGTAATTAT 300
GACCACAAAC TGCGCCCTGG CATTGGAGAG AAGCCCACTG TGGTCACTGT TGAGATCGCC 360 βTCAACAGCC TTGGTCCTCT CTCTATCCTA GACATGGAAT ACACCATTGA CATCATCTTC 420
TCCCAGACCT GGTACGACGA ACGCCTCTGT TACAACGACA CCTTTGAGTC TCTTGTTCTG 480
AATGGCAATG TGGTGAGCCA GCTATGGATC CCGGACACCT TTTTTAGGAA TTCTAAGAGG 540
ACCCACGAGC ATGAGATCAC CATGCCCAAC CAGATGGTCC GCATCTACAA GGATGGCAAG 600
GTGTTGTACA CAATTAGGAT GACCATTGAT GCCGGATGCT CACTCCACAT GCTCAGATTT 660
CCAATGGATT CTCACTCTTC CCCTCTATCT TTCTCTAGCT TTTCCTATCC TGAGAATβAG 720
ATGATCTACA AGTGGGAAAA TTTCAAGCTT GAAATCAATβ AGAAGAACTC CTGGAAGCTC 780
TTCCAGTTTG ATTTTACAGG AβTβAGCAAC AAAACTGAAA TAATCACAAC CCCAGTTGGT 840
GACTTCATGG TCATGACGAT TTTCTTCAAT GTGAGCAGGC GGTTTGGCTA TGTTGCCTTT 900
CAAAACTATG TCCCTTCTTC CGTGACCACG ATGCTCTCCT GGGTTTCCTT TTGGATCAAG 960
ACAGAGTCTG CTCCAGCCCG GACCTCTCTA GGGATCACCT CTGTTCTGAC CATGACCACG 1020
TTGGGCACCT TTTCTCβTAA GAATTTCCCG CGTGTCTCCT ATATCACAGC CTTGGATTTC 1080
TATATCGCCA TCTGCTTCGT CTTCTGCTTC TGCGCTCTGT TGGAGTTTβC TGTGCTCAAC 1140
TTCCTGATCT ACAACCAGAC AAAAGCCCAT GCTTCTCCTA AACTCCGCCA TCCTCGTATC 1200
AATAGCCGTG CCCATGCCCG TACCCGTGCA CGTTCCCGAG CCTGTGCCCG CCAACATCAG 1260
GAAGCTTTTG TGTGCCAGAT TGTCACCACT GAGGGAAGTG ATGGAGAGGA GCGCCCGTCT 1320
TGCTCAGCCC AGCAGCCCCC TAGCCCAβGT AGCCCTGAGβ GTCCCCGCAG CCTCTGCTCC 1380
AAGCTGGCCT βCTGTGAGTG GTGCAAGCGT TTTAAGAAGT ACTTCTGCAT GGTCCCCGAT . 1440
TGTGAGGGCA GTACCTGGCA GCAGGGCCGC CTCTGCATCC ATGTCTACCG CCTGGATAAC 1500
TACTCGAGAG TTGTTTTCCC AGTGACTTTC TTCTTCTTCA ATGTGCTCTA CTGGCTTGTT 1560
TGCCTTAACT TGTAGGTACC AGCTGGTACC CTGTGGGGCA ACCTCTCCAG TTCCCCAGGA 1620
GGTCCAAGCC CCTTGCCAAG GGAGTTGGGG GAAAGCAGCA GCAGCAGCAβ GAGCGACTAG 1680
AGTTTTTCCT GCCCCATTCC CCAAACAGAA GCTTGCAGAG GGTTTGTCTT TGCTGCCCCT 1740
CTCCCCTACC TGGCCCATTC ACTGAGTCTT CTCAGCAGAC CATTTCAAAT TATTAATAAA 1800
TGGGCCACCT CCCTCTTCTT CAAGGAGCAT CCGTGATGCT CAGTGTTCAA AACCACAGCC 1860
ACTTAGTGAT CAGCTCCCTA AAACCATGCC TAAGTACAGG CGGATTAGCT ATCTTCCAAC 1920
AATGCTGACC ACCAGACAAT TACTGCATTT TTCCAGAAβC CCACTATTGC CTTTGTAGTG 1980
CTTTCGGCCC AGTTCTGGCC TCAGCCTCAA AGTGCACCGA CTAGTTGCTT GCCTATACCT 2040
GGCACCTCAT TAAGATGCTG GGCAGCAGTA TAACAGβAGG AAGAGATCCC TCTCCTTTGG 2100
TCAGATTATT ATGTTCTCAG TTCTCTCTCC CTGCTACCCC TTTCTCTGCA GATAGATAGA 2160
CACTGGCATT ATCCCTTTAG GAAGAGGGGG GGGCAGCAAG AGAGCCTATT TGGGACAGCA 2220
TTCCTCTCTC TCTGCTGCTG TGACATCTCC CTCTCCTTGC TGGCTCCATC TTTCGTCTGC 2280
ACTACCAATT CAATCCCCTT CATCCAATGG GTATCTATTT TTGTGT6TGA TTATAGTAAC 2340
TACTCCCTGC TTTATATGCC ACCCTCTTCC TTCTCTTTGA CCCCTGTGAC TCTTTCTGTA 2400
ACTTTCCCAG TGACTTCCCC TAGCCCTGAC CCAGGCACTA GGCCTTGGTG ACTTCCTGββ 2460
GCCAAGAAAC TAAGGAAACT CGGCTTTGCA ACAGGCATTA CTCGCCATTG ATTGGTGCCC 2520
ACCCAGGGCA CACTGTCGGA GTTCTATCAC TTGCTTGACC CCTGGACCCA TAAACCACTC 2580
CACTGTTATA CCCGGGGCAC TCTAACCATC ACAATCAATC AATCAAATTC CCTTAAATTT 2640
GTATββCACT GGAACTTTGG CAAAGCACTT TTGACAAGTT GTCTCT6ATT GGAGCTTCAT 2700
GATAGCCTTG TGACATCTTT AGGGCAGGAT TCTTATCCCC ATTTTGCAGA TGAAAACCCT 2760
GAGTCACAGA TTTCTGTGGG ACTGTGGATC TCACTGGAAG CTATCCAAGA GCCCACTGTC 2820
ACCTTCTAGA CCACATGATA GGGCTAGACA GGTCACTTCA CCATGATTCT CTTCTGTCAC 2880
CTCTGCTGGC ACACCAGTGG CAAGGCCCAG AATGGCGACC TCTCTTTAGC TCAATTTCTG 2940
GGCCTGAGGT GCTCAGACTG CCCCCAAGAT CAAATCTCTC CTGGCTGTAG TAACCCAGTG 3000
GAATGAATTT GGACATGCCC CAATGCTTCT ATATGCTAAG TGAAATCTGT GTCTGTAATT 3060 TGTTGGGGGG TGGATAGGGT GGGGTCTCCA TCTACTTTTT GTCACCATCA TCTGAAATGG 3120 GGAAATATGT AAATAAATAT ATCAGCAAAG CAAAAAGAAA AAAAAAAA
Seq ID NO: 610 Protein sequence Protein Accession ft: NP 004952.1
11 21 31 41 51
I I I I I
MLSKVLPVLL GILLILQSRV EGPQTESKNE ASSRD YβP QPQPLENQLL SEETKSTETE 60 TGSRVGKLPE ASRILNTILS NYDHKLRPGI βEKPT TVE IAVNSLGPLS ILDMEYTIDI 120 IFSQTWYDER LCYNDTFESL VLNβN SQL WIPDTFFRNS KRTHEHEITM PNQMVRIYKD 180 GKVLYTIRMT IDAGCSLHML RFPMDSHSCP LSFSSFSYPE NEMIYKWENF KLEINEKNSW 240 KLFQFDFTβV SNKTEIITTP VGDFMVMTIF FNVSRRFGYV AFQNYVPSSV TTMLSWVSFW 300 IKTESAPART SLGITSVLTM TTLGTFSRKN FPRVSYITAL DFYIAICFVF CFCALLEFAV 360 LNFLIYNQTK AHASPKLRHP RINSRAHART RARSRACARQ HQEAFVCQIV TTEGSDGEER 420 PSCSAQQPPS PGSPEGPRSL CSKLACCEWC KRFKKYFCMV PDCEGSTWQQ GRLCIHVYRL 480 DNYSRWFPV TFFFFNVLYW LVCLNL
Seq ID NO: 611 DNA sequence
Nucleic Acid Accession ft: NM_021984.1
Coding sequence: 572..1753
11 21 31 41 51
I I I I I
GCCAGAGCGT GAGCCGCGAC CTCCGCGCAG GTGGTCGCGC CGGTCTCCGC GGAAATGTTG 60 TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAGTCGAG AACATGTATA 120 CAGAGAAGTG CTCAAATCAT AAGTGTACAG CTGATGAGTT GTCAAAAAAT GACCACAGCβ 180 GTGTAAAGAA AGCCAAATCA AGGACCCGAA TGTGAGCAGG ACCTCAGAAG CCCCCTTTGT 240 CACTGCCTCC CAGCAAAGGC AGCACTATCC GGACTTCTAA CACCATCGGβ TCGAGGGACC 300 TCAGACTGAA TCAAAGAATG AAβCCTCTTC CCGTGATGTT GTCTATGGCC CCCAGCCCCA 360 GCCTCTGGAA AATCAGCTCC TCTCTβAGGA AACAAAGTCA ACTGAGACTG AGACTGGGAG 420 CAGAβTTGGC AAACTGCCAG AAGCCTCTCG CATCCTGAAC ACTATCCTGA GTAATTATGA 480 CCACAAACTG CGCCCTGGCA TTGGAGAGAA GCCCACTGTG GTCACTGTTG AGATCTCCGT 540 CAACAGCCTT GGTCCTCTCT CTATCCTAβA CATβGAATAC ACCATTGACA TCATCTTCTC 600 CCAGACCTGβ TACGACGAAC GCCTCTGTTA CAACGACACC TTTGAGTCTC TTGTTCTGAA 660 TGGCAATGTβ GTGAGCCAGC TATGGATCCC GGACACCTTT TTTAβGAATT CTAAGAGGAC 720 CCACGAGCAT GAβATCACCA TβCCCAACCA GATGβTCCGC ATCTACAAGG ATGGCAAGGT 780 GTTGTACACA ATTAGβATGA CCATTGAT6C CββATβCTCA CTCCACATGC TCAGATTTCC 840 AATGGATTCT CACTCTTGCC CTCTATCTTT CTCTAGCTTT TCCTATCCTβ AGAATGAGAT 900 GATCTACAAG TGGGAAAATT TCAAGCTTGA AATCAATGAG AAβAACTCCT GGAAGCTCTT 960 CCAGTTGGAT TTTACAGGAβ TβAβCAACAA AACT6AAATA ATCACAACCC CAGTTGGTGA 1020 CTTCATGGTC ATGACGATTT TCTTCAATβT βAβCAβGCGβ TTTGGCTATG TTGCCTTTCA 1080 AAACTATGTC CCTTCTTCCG TGACCACβAT βCTCTCCTGG GTTTCCTTTT GGATCAAGAC 1140 AGAGTCTGCT CCAGCCCGGA CCTCTCTA6G GATCACCTCT GTTCTGACCA TGACCACGTT 1200 GGGCACCTTT TCTCGTAAGA ATTTCCCGCG TGTCTCCTAT ATCACAGCCT TGGATTTCTA 1260 TATCGCCATC TGCTTCGTCT TCTGCTTCTG CGCTCTGTTG GAGTTTGCTG TGCTCAACTT 1320 CCTGATCTAC AACCAGACAA AAGCCCATGC TTCTCCTAAA CTCCGCCATC CTCGTATCAA 1380 TAGCCGTGCC CATGCCCGTA CCCGTGCACG TTCCCGAGCC TGTGCCCGCC AACATCAGGA 1440 AGCTTTTGTG TGCCAGATTG TCACCACTGA GGGAAGTGAT GGAGAGGAGC GCCCGTCTTG 1500 CTCAGCCCAG CAGCCCCCTA GCCCAGGTAG CCCTGAGGGT CCCCGCAGCC TCTGCTCCAA 1560 GCTGGCCTGC TGTGAGTGβT βCAAGCGTTT TAAGAAGTAC TTCTGCATGG TCCCCGATTG 1620 TGAGGGCACT ACCTGGCAGC AGGCCCβCCT CTGCATCCAT GTCTACCGCC TGGATAACTA 1680 CTCGAGAGTT GTTTTCCCAG TβACTTTCTT CTTCTTCAAT GTGCTCTACT GGCTTGTTTG 1740 CCTTAACTTG TAGGTACCAG CTGGTACCCT GTGGGGCAAC CTCTCCAβTT CCCCAGGAGG 1800 TCCAAGCCCC TTGCCAAGGG AGTTGGGGGA AAGCAGCAGC AGCAGCAGGA GCGACTACAβ 1860 TTTTTCCTGC CCCATTCCCC AAACAGAAGC TTGCAGAGGG TTTGTCTTTG CTGCCCCTCT 1920 CCCCTACCTG GCCCATTCAC TGAβTTTTCT CAGCAGACCA TTTCAAATTA TTAATAAATG 1980 GGCCACCTCC CTCTTCTTCA AGGAGCATCC GTGATGCTCA GTGTTCAAAA CCACAGCCAC 2040 TTAGTGATCA GCTCCCTAAA ACCATGCCTA AGTACAGGCG GATTAGCTAT CTTCCAACAA 2100 TGCTGACCAC CAGACAATTA CTGCATTTTT CCAGAAGCCC ACTATTGCCT TTGCAGTGCT 2160 TTCGGCCCAG TTCTGGCCTC AGCCTCAAAβ TGCACCGACT AGTTβCTTCC CTATACCTGG 2220 CACCTCATTA AGATGCTGGβ CAGCAGTATA ACAGGAGGAA GAGATCCCTC TCCTTTGGTC 2280 AGATTATTAT GTTCTCAGTT CTCTCTCCCT GCTACCCCTT TCTCTβCAβA TAGATA6ACA 2340 CTGGCATTAT CCCTTTAGGA AGAGGGGGGG GCAGCAAGAG AGCCTATTTG GGACAGCATT 2400 CCTCTCTCTC TGCTGCTGTβ ACATCTCCCT CTCCTTGCTG GCTCCATCTT TCGTCTGCAC 2460 TACCAATTCA ATGCCCTTCA TCCAATGGGT ATCTATTTTT GTGTGTGATT ATAGTAACTA 2520 CTCCCTGCTT TATATGCCAC CCTCTTCCTT CTCTTTGACC CCTGTGACTC TTTCTGTAAC 2580 TTTCCCAGTG ACTTCCCCTA GCCCTGACCC AGGCACTAGG CCTTGGTGAC TTCCTGGGGC 2640 CAAGAAACTA AGGAAACTCG GCTTTGCAAC AGGCATTACT CGCCATTGAT TGGTGCCCAC 2700 CCAGGGCACA CTGTCGGAGT TCTATCACTT GCTTGACCCC TGGACCCATA AACCAGTCCA 2760 CTGTTATACC CGGGGCACTC TAACCATCAC AATCAATCAA . TCAAATTCCC TTAAATTTGT 2820 ATGGCACTGβ AACTTTGGCA AAGCACTTTT GACAAGTTGT GTCTβATTGG AGCTTCATGA 2880 TAGCCTTGTG ACATCTTTAG GGCAGGATTC TTATCCCCAT TTTGCAGATG AAAACCCTGA 2940 GTCACAGATT TCTGTβGGAC TGTGGATCTC ACTGGAAGCT ATCCAAGAGC CCACTGTCAC 3000 CTTCTAGACC ACATGATAβG GCTAGACAGC TCAGTTCACC : ATGATTCTCT TCTGTCACCT 3060 CTGCTGGCAC ACCAGTGGCA AGGCCCAGAA TGGCGACCTC ! TCTTTAGCTC AATTTCTGGG 3120 CCTβAGGTGC TCAGACTGCC CCCAAGATCA AATCTCTCCT ' GGCTGTAGTA ACCCAGTGGA 3180 ATGAATTTGG ACATGCCCCA ATGCTTCTAT ATGCTAAGTG 1 AAATCTGTGT CTGTAATTTG 3240 TTGGGGGGTG GATAGGGTGG GGTCTCCATC TACTTTTTGT ' CACCATCATC TGAAATGGGG 3300 AAATATGTAA ATAAATATAT CAGCAAAGC
Seq ID NO: 612 Protein sequence Protein Accession ft: NP 068819.1 1 11 21 31 41 51
1 1 1 1 | 1 | 1 |1 MEYTIDIIFS QTWYDERLCY NDTFESLVLN GNWSQLWIP DTFFRNSKRT HEHEITMPNQ 60
MVRIYKDGKV LYTIRMTIDA GCSLHMLRFP MDSHSCPLSF SSFSYPENEM lYKWENFKLE 120
INEKNSWKLF QLDFTGVSNK TEIITTPVGD FMVMTIFFNV SRRFGYVAFQ NYVPSSVTTM 180
LSWVSFWIKT ESAPARTSLG ITSVLTMTTL GTFSRKNFPR VSYITALDFY IAICFVFCFC 240
ALLEFAVLNF LIYNQTKAHA SPKLRHPRIN SRAHARTRAR SRACARQHQE AFVCQIVTTE 300
GSDGEERPSC SAQQPPSPGS PEGPRSLCSK LACCEWCKRF KKYFCMVPDC EGSTWQQARL 360
CIHVYRLDNY SRWFPVTFF FFNVLYWLVC LNL
Seq ID NO: 613 DNA sequence
Nucleic Acid Accession ft: NM_021987.1 Coding sequence: 572..1657
1 11 21 31 41 51
I I I I I I
GCCAGAGCGT GAGCCβCGAC CTCCGCGCAG GTGGTCGCβC CGGTCTCCGC GβAAATGTTG 60
TCCAAAβTTC TTCCA6TCCT CCTAGGCATC TTATTGATCC TCCAGTCGAG AACATGTATA 120
CAGAGAAGTG CTCAAATCAT AAGTGTACAG CTGATGAβTT βTCAAAAAAT GACCACAGCG 180
GTGTAAAGAA AGCCAAATCA AGGACCCGAA TGTGAGCAGG ACCTCAGAAG CCCCCTTTGT 240
CACTGCCTCC CAGCAAAGGC AGCACTATCC GGACTTCTAA CACCATCGGG TCGAGGGACC 300
TCAGACTGAA TCAAAGAATG AAGCCTCTTC CCGTGATGTT GTCTATGGCC CCCAGCCCCA 360
GCCTCTββAA AATCAGCTCC TCTCTGAGGA AACAAAGTCA ACTGAGACTG AGACTGGGAG 420
CAGAGTTGGC AAACTGCCAG AAGCCTCTCG CATCCTGAAC ACTATCCTGA GTAATTATGA 480
CCACAAACTG CGCCCTGGCA TTGGAGAGAA GCCCACTGTG GTCACTGTTG AGATCTCCGT 540
CAACAGCCTT GGTCCTCTCT CTATCCTAGA CATGβAATAC ACCATTGACA TCATCTTCTC 600
CCAGACCTGG AATTCTAAGA GGACCCACGA GCATGAβATC ACCATGCCCA ACCAGATGGT 660
CCGCATCTAC AAGGATGGCA AGGTGTTGTA CACAATTAGG ATGACCATTG ATGCCGGATG 720
CTCACTCCAC ATGCTCAGAT TTCCAATGGA TTCTCACTCT TCCCCTCTAT CTTTCTCTAβ 780
CTTTTCCTAT CCTGAGAATG AGATGATCTA CAAGTGGGAA AATTTCAAGC TTGAAATCAA 840
TGAGAAGAAC TCCTGGAAGC TCTTCCAGTT TGATTTTACA GβAβTGAGCA ACAAAACTGA 900
AATAATCACA ACCCCAGTTG GTGACTTCAT GGTCATGACG ATTTTCTTCA ATGTGAGCAG 960
GCGGTTTGGC TATGTTGCCT TTCAAAACTA TGTCCCTTCT ' TCCGTGACCA CGATGCTCTC 1020
CTGGGTTTCC TTTTGβATCA AGACAGAGTC TGCTCCAGCC CGGACCTCTC TAGGGATCAC 1080
CTCTGTTCTG ACCATGACCA CGTTGGGCAC CTTTTCTCβT AAGAATTTCC CGCGTGTCTC 1140
CTATATCACA GCCTTGGATT TCTATATCβC CATCTβCTTC GTCTTCTGCT TCTGCGCTCT 1200
GTTGGAβTTT GCTGTGCTCA ACTTCCTGAT CTACAACCAβ ACAAAAGCCC ATGCTTCTCC 1260
TAAACTCCGC CATCCTCGTA TCAATAGCCG TGCCCATGCC CGTACCCGTG CACGTTCCCG 1320
AGCCTβTβCC CGCCAACATC AGGAAGCTTT TGTGTGCCAG ATTGTCACCA CTGAGGGAAG 1380
TGATGGAGAG GAGCGCCCGT CTTGCTCAGC CCAGCAGCCC CCTAGCCCAG GTAGCCCTGA 1440 ββGTCCCCGC AGCCTCTGCT CCAAGCTGGC CTGCTGTGAG TGGTGCAAGC GTTTTAAGAA 1500
GTACTTCTβC ATGGTCCCCG ATTGTGAGGG CAGTACCTGG CAGCAGGGCC GCCTCTGCAT 1560
CCATGTCTAC CGCCTG6ATA ACTACTCGAG AGTTGTTTTC CCAGTGACTT TCTTCTTCTT 1620
CAATβTβCTC TACTGGCTTG TTTGCCTTAA CTTGTAGβTA CCAGCTGGTA CCCTGTGGGG 1680
CAACCTCTCC AGTTCCCCAG βAGGTCCAAG CCCCTTGCCA AGGGAGTTGG GGGAAAGCAG 1740
CAGCAGCAGC AGGAGCGACT AGAGTTTTTC CTGCCCCATT CCCCAAACAG AAGCTTGCAG 1800
AGGGTTTGTC TTTGCTGCCC CTCTCCCCTA CCTGGCCCAT TCACTGAGTT TTCTCAGCAG 1860
ACCATTTCAA ATTATTAATA AATGGGCCAC CTCCCTCTTC TTCAAGGAGC ATCCGTGATG 1920
CTCAGTGTTC AAAACCACAG CCACTTAGTG ATCAGCTCCC TAAAACCATG CCTAAGTACA 1980
GGCGGATTAG CTATCTTCCA ACAATGCTGA CCACCAGACA ATTACTGCAT TTTTCCAGAA 2040
GCCCACTATT GCCTTTGCAG TGCTTTCGGC CCAGTTCTGG CCTCAGCCTC AAAGTGCACC 2100
GACTAGTTGC TTGCCTATAC CTGGCACCTC ATTAAGATGC TGGGCAGCAG TATAACAGGA 2160
GGAAGAGATC CCTCTCCTTT GGTCAGATTA TTATGTTCTC AGTTCTCTCT CCCTGCTACC 2220
CCTTTCTCTG CAGATAGATA GACACTGGCA TTATCCCTTT A6GAAGAGGG GββGGCAGCA 2280
AGAGAGCCTA TTTGGGACAG CATTCCTCTC TCTCTGCTGC TGTβACATCT CCCTCTCCTT 2340
GCTGGCTCCA TCTTTCGTCT GCACTACCAA TTCAATGCCC TTCATCCAAT GGGTATCTAT 2400
TTTTGTGTGT GATTATAGTA ACTACTCCCT GCTTTATATG CCACCCTCTT CCTTCTCTTT 2460
GACCCCTGTG ACTCTTTCTG TAACTTTCCC AGTGACTTCC CCTAGCCCTG ACCAGGCACT 2520
AGGCCTTGGT GACTTCCTGG GGCCAAGAAA CTAAGGAAAC TCGGCTTTGC AACAGGCATT 2580
ACTCGCCATT GATTGGTGCC CACCCAGGGC ACACTGTCGG AGTTCTATCA CTTGCTTGAC 2640
CCCTGGACCC ATAAACCAGT CCACTGTTAT ACCCGGGGCA CTCTAACCAT CACAATCAAT 2700
CAATCAAATT CCCTTAAATT TGTATGβCAC TGGAACTTTG GCAAAGCACT TTTGACAAGT 2760
TGTGTCTGAT TGGAGCTTCA TGATAGCCTT GTGACATCTT TAGGGCAGGA TTCTTATCCC 2820
CATTTTGCAG ATGAAAACCC TGAGTCACAG ATTTCTGTGG GACTβTGGAT CTCACTGGAA 2880
GCTATCCAAG AGCCCACTGT CACCTTCTAG ACCACATGAT AGGGCTAGAC AGCTCAGTTC 2940
ACCATGATTC TCTTCTGTCA CCTCTGCTGG CACACCAGTG GCAAββCCCA βAATGGCGAC 3000
CTCTCTTTAG CTCAATTTCT GββCCTGAGG TGCTCAGACT GCCCCCAAGA TCAAATCTCT 3060
CCTGGCTGTA GTAACCCAGT GβAATGAATT TGGACATGCC CCAATGCTTC TATATGCTAA 3120
GTGAAATCTG TGTCTGTAAT TTGTTGGGGG GTGGATAGGG TGβGGTCTCC ATCTACTTTT 3180 TGTCACCATC ATCTGAAATG GGGAAATATG TAAATAAATA TATCAGCAAA GC
Seq ID NO: 614 Protein sequence Protein Accession ft: NP_068822.1
1 11 21
MEYTIDIIFS QTWNSKRTHE HEITMPNQMV RIYKDGKVLY TIRMTIDAGC SLHMLRFPMD 60
SHSCPLSFSS FSYPENEMIY KWENFKLEIN EKNSWKLFQF DFTGVSNKTE IITTPVGDFM 120
VMTIFFNVSR RFGYVAFQNY VPSSVTTMLS WVSFWIKTES APARTSLβlT SVLTMTTLβT 180
FSRKNFPRVS YITALDFYIA ICFVFCFCAL LEFAVLNFLI YNQTKAHASP KLRHPRINSR 240
AHARTRARSR ACARQHQEAF VCQIVTTEGS DGEERPSCSA QQPPSPGSPE 6PRSLCSKLA 300
CCEWCKRFKK YFCMVPDCEG STWQQGRLCI HVYRLDNYSR WFPVTFFFF NVLYWLVCLN 360 L Seq ID NO: 615 DNA sequence
Nucleic Acid Accession ff: NM_021990.1
Coding sequence: 1309..2490
1 11 21 31 41 51
I I I I I I
GCCAGAGCGT GAGCCGCGAC CTCCGCGCAG βTGGTCGCGC CGGTCTCCGC GGAAATGTTG 60
TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAβTCβAG AACATGTATA 120
CAGAGAAGTβ CTCAAATCAT AAGTGTACAG CTβATGAGTT GTCAAAAAAT GACCACAGCG 180 0 GTGTAAAGAA AGCCAAATCA AGGACCCGAA TGTGAGCAGG ACCTCAGAAG CCCCCTTTGT 240
CACTGCCTCC CAGCAAAGGC AGCACTATCC GGACTTCTAA CACCATCGGT GAGTTTCATA 300
CCTTGGCAGA TGGCCTTTAA CATTTTTGTT TAATTCAATT ATTCTTACTA ATCTTCTTCT 360
TTTTCTTGGC TGTGGTGCAT GGCTGTGGAG CTCAGGGTGG ACTCCTGTTβ GGCAGCCAGT 420
TCCTGGATGG CTGTCTGTGG GTGGAGGACT CCTGCCTTTC CTGTTTAGAC ACCCACAAAG 480 5 GCTGCTCTTT AGCCTCCTTC CCTTCATCCC CTTCCCCTGC CCCCAGTGCA ACGAGTATTA 540
CACAACCAAC AAAACCGCAA AATATTCCCA CAATTTTCTG GTCCTCTCTG GGAGAGGCCβ 600
CTCTGGCTTT TCCTCTCAGC CCTGGCCCTC TGCCTGCTCC TCACTCCTGG TTGGTGCTGβ 660
TCAGGCTGAC TAGAGGCCAA GGCGACCAAC ACTAGGCAAA CGCGGCCAGC GCTCAGACAT 720
AAATGCCCTC TTCATTTCAC GTGTAACATT CTTTTAAAAT CTAGGTCTTG GTTTTGTTGA 780 0 TTTTTTCTTA AATAAAAGAG TGATCATAAA AGAGGGACAβ CATAGAAAGT CCCCAAAGAβ 840
CAGCAAGGTT TTAAAGAAAT TCACAAGCCT AATCTGTCAC TGTCTTATAA TTTGCTATTA 900
CCAGTCACAA TTTAACTAGG TTTTGTGTTG AAAACTTGTT TTGGTTTGCT TCTGTCCCAA 960
GAGGCACTAG CTGGGGCCCC TACAGAGTGC AGGGCAGAGC TTCATTTTTC GTTTGAATGT 1020
TCTAGGGTCG AGGGACCTCA GACTGAATCA AAGAATGAAG CCTCTTCCCG TGATGTTGTC 1080 5 TATGGCCCCC AGCCCCAGCC TCTGGAAAAT CACCTGCTCT CTGAGGAAAC AAAGTCAACT 1140
GAGACTGAGA CTGGGAGCAG AGTTGGCAAA CTGCCAβAAβ CCTCTCGCAT CCTGAACACT 1200
ATCCTGAGTA ATTATGACCA CAAACTGCGC CCTGGCATTG GAGAGAAGCC CACTGTGβTC 1260
ACTGTTGAGA TCTCCGTCAA CAGCCTTGGT CCTCTCTCTA TCCTAGACAT GGAATACACC 1320
ATTGACATCA TCTTCTCCCA GACCTGGTAC GACGAACGCC TCTGTTACAA CGACACCTTT 1380 0 GAGTCTCTTG TTCTGAATGG CAATGTGGTG AGCCAGCTAT GGATCCCGGA CACCTTTTTT 1440
AGGAATTCTA AGAGGACCCA CGAGCATGAG ATCACCATGC CCAACCAGAT GβTCCGCATC 1500
TACAAGGATG GCAAGGTGTT GTACACAATT AGGATGACCA TTGATGCCGG ATβCTCACTC 1560
CACATGCTCA GATTTCCAAT GGATTCTCAC TCTTGCCCTC TATCTTTCTC TAGCTTTTCC 1620
TATCCTGAGA ATGAGATGAT CTACAACTGG GAAAATTTCA AGCTTGAAAT CAATGAGAAG 1680 5 AACTCCTGβA AGCTCTTCCA GTTTGATTTT ACAGGAGTGA GCAACAAAAC TGAAATAATC 1740
ACAACCCCAG TTGGTGACTT CATGGTCATG ACGATTTTCT TCAATGTGAG CAGGCGGTTT 1800
GGCTATGTTG CCTTTCAAAA CTATGTCCCT TCTTCCGTGA CCACGATGCT CTCCTGGGTT 1860
TCCTTTTGGA TCAAGACAGA GTCTCCTCCA GCCCGGACCT CTCTAGβGAT CACCTCTβTT 1920
CTGACCATGA CCACGTTGGG CACCTTTTCT CGTAAGAATT TCCCGCCTGT CTCCTATATC 1980 0 ACAGCCTTGβ ATTTCTATAT CGCCATCTGC TTCGTCTTCT GCTTCTGCGC TCTGTTGGAG 2040
TTTGCTGTβC TCAACTTCCT GATCTACAAC CAGACAAAAG CCCATβCTTC TCCTAAACTC 2100
CGCCATCCTC GTATCAATAG CCGTGCCCAT GCCCGTACCC GTβCACβTTC CCGAGCCTGT 2160
GCCCGCCAAC ATCAGGAAGC TTTTGTGTGC CAGATTGTCA CCACTGAGGG AAGTGATGGA 2220
GAGGAGCeCC CGTCTTGCTC AGCCCAGCAG CCCCCTAGCC CAGβTAGCCC TGAGGGTCCC 2280 5 CGCACCCTCT βCTCCAAGCT GGCCTGCTGT GA6TGGTGCA AGCGTTTTAA GAAGTACTTC 2340
TGCATGGTCC CCGATTGTGA GGGCAGTACC TGGCAGCAGβ GCCGCCTCTG CATCCATGTC 2400
TACCGCCTGG ATAACTACTC GAGAGTTGTT TTCCCACTGA CTTTCTTCTT CTTCAATGTG 2460
CTCTACTGGC TTGTTTGCCT TAACTTGTAG GTACCAGCTG GTACCCTGTG GGGCAACCTC 2520
TCCAGTTCCC CAGGAGGTCC AAGCCCCTTG CCAAGGGAGT TGGGGGAAAG CAGCAGCAGC 2580 0 AGCAGGAGCβ ACTAGAGTTT TTCCTGCCCC ATTCCCCAAA CAGAAGCTTG CAGAGGGTTT 2640
GTCTTTGCTG CCCCTCTCCC CTACCTGGCC CATTCACTGA GTTTTCTCAG CAGACCATTT 2700
CAAATTATTA ATAAATGGGC CACCTCCCTC TTCTTCAAGG AGCATCCGTG ATGCTCAGTG 2760
TTCAAAACCA CAGCCACTTA GTβATCAβCT CCCTAAAACC ATGCCTAAGT ACAGGCGGAT 2820
TAGCTATCTT CCAACAATGC TGACCACCAG ACAATTACTG CATTTTTCCA GAAβCCCACT 2880 5 ATTGCCTTTG CAGTGCTTTC GGCCCAGTTC TGGCCTCA6C CTCAAAβTGC ACCGACTACT 2940
TGCTTGCCTA TACCTGβCAC CTCATTAAGA TGCTGGGCAβ CAGTATAACA GGAGGAAGAβ 3000
ATCCCTCTCC TTTββTCAGA TTATTATGTT CTCAGTTCTC TCTCCCTGCT ACCCCTTTCT 3060
CTGCAGATAG ATAGACACTG GCATTATCCC TTTAGGAAGA GGGGGGGGCA GCAAGAGAGC 3120
CTATTTGGGA CAGCATTCCT CTCTCTCTGC TGCTGTGACA TCTCCCTCTC CTTGCTGGCT 3180 0 CCATCTTTCG TCTGCACTAC CAATTCAATG CCCTTCATCC AATGGGTATC TATTTTTGTβ 3240
TGTGATTATA GTAACTACTC CCTGCTTTAT ATGCCACCCT CTTCCTTCTC TTTGACCCCT 3300
GTGACTCTTT CTGTAACTTT CCCAGTGACT TCCCCTAGCC CTGACCAGGC ACTAGGCCTT 3360
GGTGACTTCC TGGGGCCAAG AAACTAAGGA AACTCGGCTT TGCAACAGGC ATTACTCGCC 3420
ATTGATTGGT GCCCACCCAG GGCACACTGT CGGAGTTCTA TCACTTGCTT GACCCCTGGA 3480 5 CCCATAAACC AGTCCACTGT TATACCCGββ βCACTCTAAC CATCACAATC AATCAATCAA 3540
ATTCCCTTAA ATTTβTATGG CACTGGAACT TTGGCAAAGC ACTTTTGACA AGTTGTβTCT 3600 βATTGGAGCT TCATGATAGC CTTGTGACAT CTTTAGGβCA ββATTCTTAT CCCCATTTTG 3660
CAGATGAAAA CCCTGAGTCA CAGATTTCTG TGGGACTβTG GATCTCACTG GAAGCTATCC 3720
AAGAGCCCAC TGTCACCTTC TAGACCACAT GATAGGGCTA GACAGCTCAG TTCACCATGA 3780 0 TTCTCTTCTG TCACCTCTGC TGGCACACCA GTGGCAAGGC CCAGAATGGC GACCTCTCTT 3840
TAGCTCAATT TCTGGGCCTG AGβTβCTCAG ACTGCCCCCA AGATCAAATC TCTCCTGGCT 3900
GTAGTAACCC AGTGGAATGA ATTTGGACAT GCCCCAATGC TTCTATATGC TAAGTGAAAT 3960
CTGTGTCTβT AATTTGTTGG GGGGTGGATA GGGTGGGGTC TCCATCTACT TTTTGTCACC 4020 ATCATCTGAA ATGGGGAAAT ATGTAAATAA ATATATCAβC AAAGC
75
Seq ID NO : 616 Protein sequence Protein Accession it : NP 068830 . 1
_, Λ 1 11 21 31 41 51
80 i i i i i i
MEYTIDIIFS QTWYDERLCY NDTFESLVLN GNWSQLWIP DTFFRNSKRT HEHEITMPNQ 60
MVRIYKDGKV LYTIRMTIDA GCSLHMLRFP MDSHSCPLSF SSFSYPENEM IYKWENFKLE 120
INEKNSWKLF QFDFTGVSNK TEIITTPVGD FMVMTIFFNV SRRFGYVAFQ NYVPSΞVTTM 180
LSWVSFWIKT ESAPARTSLG ITSVLTMTTL GTFSRKNFPR VSYITALDFY IAICFVFCFC 240 ALLEFAVLNF LIYNQTKAHA SPKLRHPRIN SRAHARTRAR SRACARQHQE AFVCQIVTTE 300 GSDGEERPSC SAQQPPSPGS PEGPRSLCSK LACCEWCKRF KKYFCMVPDC EGSTWQQGRL 360 CIHVYRLDNY SRWFPVTFF FFNVLYWLVC LNL
Seq ID NO: 617 DNA sequence
Nucleic Acid Accession ft: NM_004864.1
Coding sequence: 26..952
11 21 31 41 51
I I I I I
CGCAACGAGG GCAACCTGCA CAGCCATGCC CGGGCAAGAA CTCAGGACGG TGAATGGCTC 60 TCAGATGCTC CTGGTGTTGC TGGTGCTCTC GTGGCTGCCG CATGGGGGCG CCCTGTCTCT 120 GGCCGAGGCG AGCCGCGCAA GTTTCCCGGG ACCCTCAGAG TTGCACTCCG AAGACTCCAG 180 ATTCCGAGAG TTGCGGAAAC GCTACGAGGA CCTGCTAACC AGGCTGCGGG CCAACCAGAG 240 CTGGGAAGAT TCGAACACCG ACCTCGTCCC GGCCCCTGCA GTCCGGATAC TCACGCCAGA 300 AGTGCGGCTG GGATCCGGCG GCCACCTGCA CCTGCGTATC TCTCGGGCCG CCCTTCCCGA 360 GGGGCTCCCC GAGGCCTCCC GCCTTCACCG GGCTCTGTTC CGGCTGTCCC CGACGGCGTC 420 AAGGTCGTGG GACGTGACAC GACCGCTGCG GCGTCAGCTC AGCCTTGCAA GACCCCAAGC 480 GCCCGCGCTG CACCTGCGAC TGTCGCCGCC GCCGTCGCAG TCGGACCAAC TGCTGGCAGA 540 ATCTTCGTCC GCACGGCCCC AGCTGGAGTT GCACTTGCGG CCGCAAGCCG CCAGGβGGCG 600 CCGCAGAGCG CGTGCGCGCA ACGGGGACGA CTGTCCGCTC GGGCCCGGGC GTTGCTGCCG 660 TCTGCACACG GTCCGCGCGT CGCTGGAAGA CCTGGGCTGG GCCGATTGGG TGCTGTCGCC 720 ACGGGAGGTG CAAGTGACCA TGTGCATCGG CGCGTGCCCG AGCCAGTTCC GGGCGGCAAA 780 CATGCACGCG CAGATCAAGA CGAGCCTGCA CCGCCTGAAG CCCGACACGG AGCCAGCGCC 840 CTGCTGGGTG CCCGCCAGCT ACAATCCCAT GGTGCTCATT CAAAAGACCG ACACCGGGGT 900 GTCGCTCCAG ACCTATGATG ACTTGTTAGC CAAAGACTGC CACTGCATAT GAGCAGTCCT 960 GGTCCTTCCA CTGTGCACCT GCGCGGGGGA GGCGACCTCA GTTGTCCTGC CCTGTβGAAT 1020 GGGCTCAAGG TTCCTGAGAC ACCCGATTCC TGCCCAAACA GCTGTATTTA TATAAGTCTG 1080 TTATTTATTA TTAATTTATT GGGGTGACCT TCTTGGGGAC TCGGGGGCTG GTCTβATGGA 1140 ACTGTGTATT TATTTAAAAC TCTGGTGATA AAAATAAAGC TGTCTGAACT GTTAAAAAAA 1200 AAAA
Seq ID NO: 618 Protein sequence Protein Accession ft: NP 004855.1
11 21 31 41 51
I I I I I
MPGQELRTVN βSQMLLVLLV LSWLPHGGAL SLAEASRASF PGPSELHSED SRFRELRKRY 60 EDLLTRLRAN QSWEDSNTDL VPAPAVRILT PEVRLGSGGH LHLRISRAAL PEGLPEASRL 120 HRALFRLSPT ASRSWDVTRP LRRQLSLARP QAPALHLRLS PPPSQSDQLL AESSSARPQL 180 ELHLRPQAAR βRRRARARNβ DDCPLβPβRC CRLHTVRASL EDLGWADWVL SPREVQVTMC 240 IGACPSQFRA ANMHAQIKTS LHRLKPDTEP APCCVPASYN PMVLIQKTDT GVSLQTYDDL 300 LAKDCHCI
Seq ID NO: 619 DNA sequence
Nucleic Acid Accession #: NM_003979.2
Coding sequence: 254..1357
11 21 31 41 51
I I I I I
ATAACAGCAT GAAGTGCCGT GGAACTGGAA TAGGCGTGTC CTCTCCCTCG ACCCTCCCCC 60 TCCTTGTCCC TCTGCTCACC CCTCGCTCGT TCCCTCCCTC CGGCGAGGGC CGCCTTTATA 120 ACAACTGCTC AGAGTGCGAG GGCGGGATAG CTGTCCAAGG TCTCCCCCAG CACTGAGGAG 180 CTCGCCTGCT GCCCTCTTGC GCGCGGGAAG CAGCACCAAG TTCACGGCCA ACGCCTTGGC 240 ACTAGGGTCC AGAATGGCTA CAACAGTCCC TGATGGTTGC CGCAATGGCC TGAAATCCAA 300 GTACTACAGA CTTTGTGATA AGGCTGAAGC TTGGGGCATC GTCCTAGAAA CGGTGGCCAC 360 AGCCGGGGTT GTGACCTCGG TGGCCTTCAT GCTCACTCTC CCGATCCTCG TCTGCAAGGT 420 GCAGGACTCC AACAGGCGAA AAATGCTGCC TACTCAGTTT CTCTTCCTCC TGGGTGTGTT 480 GGGCATCTTT GGCCTCACCT TCGCCTTCAT CATCGGACTG GACGGGAGCA CAGGGCCCAC 540 ACGCTTCTTC CTCTTTGGGA TCCTCTTTTC CATCTGCTTC TCCTGCCTGC TGGCTCATGC 600 TGTCAGTCTG ACCAAGCTCG TCCGGGGGAG GAAGCCCCTT TCCCTGTTGG TGATTCTGGG 660 TCTGGCCGTG GGCTTCAGCC TAGTCCAGGA TGTTATCGCT ATTGAATATA TTGTCCTGAC 720 CATGAATAGG ACCAACGTCA ATGTCTTTTC TGAGCTTTCC GCTCCTCGTC GCAATGAAGA 780 CTTTGTCCTC CTGCTCACCT ACGTCCTCTT CTT6ATGGCG CTGACCTTCC TCATGTCCTC 840 CTTCACCTTC TGTGGTTCCT TCACGGGCTG GAAGAGACAT GGGGCCCACA TCTACCTCAC 900 GATGCTCCTC TCCATTGCCA TCTGβGTGGC CTGGATCACC CTGCTCATGC TTCCTGACTT 960 TGACCGCAββ TGGGATGACA CCATCCTCAG CTCCGCCTTG GCTGCCAATC GCT6GGTGTT 1020 CCTGTTGGCT TATGTTAGTC CCGAGTTTTG GCTGCTCACA AAGCAACGAA ACCCCATGGA 1080 TTATCCTGTT GAGGATGCTT TCTGTAAACC TCAACTCGTG AAGAAGAGCT ATGGTGTGGA 1140 GAACAGAGCC TACTCTCAAG AGGAAATCAC TCAAGGTTTT GAAGAGACAG GGGACACGCT 1200 CTATGCCCCC TATTCCACAC ATTTTCAGCT GCAGAACCAG CCTCCCCAAA AGGAATTCTC 1260 CATCCCACGG βCCCACGCTT GGCCGAGCCC TTACAAAGAC TATGAAGTAA AGAAAGAGGG 1320 CAGCTAACTC TGTCCTGAAG AGTGGGACAA ATGCAGCCGG GCGGCAGATC TAGCGGGAGC 1380 TCAAAGGGAT GTGGGCGAAA TCTTGAGTCT TCTGAGAAAA CTGTACAAGA CACTACGGGA 1440 ACAGTTTGCC TCCCTCCCAG CCTCAACCAC AATTCTTCCA TGCTGGGGCT GATGTGGGCT 1500 AGTAAGACTC CAGTTCTTAG AGGCGCTGTA GTATTTTTTT TTTTTTGTCT CATCCTTTGG 1560 ATACTTCTTT TAAGTGGGAG TCTCAGGCAA CTCAAGTTTA GACCCTTACT CTTTTTGTTT 1620 GTTTTTTGAA ACAGGATCTT GCTCTGTCAC CCAGGCTTGA GTGCAGTGGT GCGATCACAG 1680 CCCAGTGCAG CCTCGACCAC CTGTGCTCAA GCAATCCTCC CATCTCCATC TCCCAAAGTG 1740 CTGGGATGAC AGGCGTGAGC CACAβCTCCC AGCCTAGGCC CTTAATCTTG CTGTTATTTT 1800 CCATGGACTA AAGGTCTGGT CATCTGAGCT CACGCTGGCT CACACAGCTC TAGGGGCCTG 1860 CTCCTCTAAC TCACAGTGGG TTTTGTGAGG CTCTGTGGCC CAGAGCAGAC CTGCATATCT 1920 GAGCAAAAAT AGCAAAAGCC TCTCTCAGCC CACTGGCCTG AATCTACACT GGAAGCCAAC 1980 TTGCTGGCAC CCCCGCTCCC CAACCCTTCT TGCCTGGGTA GGAGAGGCTA AAGATCACCC 2040 TAAATTTACT CATCTCTCTA GTGCTGCCTC ACATTGGGCC TCAGCAGCTC CCCAGCACCA 2100 ATTCACAGGT CACCCCTCTC TTCTTGCACT GTCCCCAAAC TTGCTGTCAA TTCCGAGATC 2160 TAATCTCCCC CTACGCTCTG CCAGGAATTC TTTCAGACCT CACTAGCACA AGCCCGβTTG 2220 CTCCTTGTCA GGAGAATTTG TAGATCATTC TCACTTCAAA TTCCTGGGGC TGATACTTCT 2280 CTCATCTTGC ACCCCAACCT CTGTAAATAG ATTTACCGCA TTTACGGCTG CATTCTGTAA 2340 GTGGGCATGG TCTCCTAATG GAβGAGTGTT CATTGTATAA TAAGTTATTC ACCTGAGTAT 2400 GCAATAAAGA TGTGGTGGCC ACTCTTTCAT GGTGGTGGCA GCAAAAAAAA AAAAAA
Seq ID NO : 620 Protein sequence Protein Accession ft : NP 003970 .1
11 21 31 41 51
I I I I
MATTVPDGCR NGLKSKYYRL CDKAEAWGIV L 1ETVATAGW TSVAFMLTLP ILVCKVQDSN 60 RRKMLPTQFL FLLGVLGIFG LTFAFIIGLD GSTGPTRFFL FGILFSICFS CLLAHAVSLT 120 KLVRGRKPLS LLVILGLAVG FSLVQDVIAI EYIVLTMNRT NVNVFSELSA PRRNEDFVLL 180 LTYVLFLMAL TFLMSSFTFC GSFTGWKRHG AHIYLTMLLΞ IAIWVAWITL LMLPDFDRRW 240 DDTILSSALA ANGWVFLLAY VSPEFWLLTK QRNPMDYPVE DAFCKPQLVK KSYGVENRAY 300 SQEEITQGFE ETGDTLYAPY STHFQLQNQP PQKEFSIPRA HAWPSPYKDY EVKKEGS
Seq ID NO: 621 DNA sequence Nucleic Acid Accession #: NM_002423.2 Coding sequence: 48..851
11 21 31 41 51
I I I I I
ACCAAATCAA CCATAGGTCC AAGAACAATT GTCTCTGGAC GGCAGCTATG CGACTCACCG 60 TGCTGTGTGC TGTGTGCCTG CTGCCTGGCA GCCTGGCCCT GCCGCTGCCT CAGGAGGCGG 120 GAβGCATGAG TGAGCTACAG TGGGAACAGG CTCAGGACTA TCTCAAGAGA TTTTATCTCT 180 ATGACTCAGA AACAAAAAAT GCCAACAGTT TAGAAGCCAA ACTGAAGGAG ATGCAAAAAT 240 TCTTTGGCCT ACCTATAACT GGAATGTTAA ACTCCCGCGT CATAGAAATA ATGCAGAAGC 300 CCAGATGTGG AGTGCCAGAT GTTGCAGAAT ACTCACTATT TCCAAATAGC CCAAAATGGA 360 CTTCCAAAGT GGTCACCTAC AGGATCGTAT CATATACTCG AGACTTACCG CATATTACAG 420 TG6ATCGATT AGTGTCAAAG GCTTTAAACA TGTGGGGCAA AGAGATCCCC CTGCATTTCA 480 GGAAAGTTβT ATGGGGAACT GCTGACATCA TGATTGGCTT TGCGCGAGGA GCTCATGGGG 540 ACTCCTACCC ATTTGATGGG CCAGGAAACA CGCTGGCTCA TGCCTTTGCG CCTGGGACAG 600 GTCTCGGAGG AGATGCTCAC TTCGATGAGG ATGAACGCTG GACGGATGGT AGCAGTCTAG 660 GGATTAACTT CCTGTATGCT GCAACTCATG AACTTGGCCA TTCTTTGGGT ATGGGACATT 720 CCTCTGATCC TAATGCAGTG ATGTATCCAA CCTATGGAAA TGGAGATCCC CAAAATTTTA 780 AACTTTCCCA GGATGATATT AAAGGCATTC AGAAACTATA TGGAAAGAGA AGTAATTCAA 840 βAAAβAAATA GAAACTTCAG GCAGAACATC CATTCATTCA TTCATTGGAT TGTATATCAT 900 TGTTGCACAA TCAGAATTGA TAAGCACTGT TCCTCCACTC CATTTAGCAA TTATGTCACC 960 CTTTTTTATT GCAGTTGGTT TTTGAATGTC TTTCACTCCT TTTATTGGTT AAACTCCTTT 1020 ATGGTβTβAC TGTGTCTTAT TCCATCTATG AGCTTTGTCA GTGCGCGTAG ATGTCAATAA 1080 ATβTTACATA CACAAATAAA TAAAATGTTT ATTCCATGGT AAATTTA
Seq ID NO : 622 Protein sequence Protein Accession # : NP 002414 .1
11 21 31 41 51 l l l l l
MRLTVLCAVC LLPGS ALPL PQEAGGMSEL QWEQAQDYLK RFYLYDSETK NANSLEAKLK 60 EMQKFFGLPI TGMLNSRVIE IMQKPRCGVP DVAEYSLFPN SPKWTSK T YRIVSYTRDL 120 PHITVDRLVS KALNMWGKEI PLHFRKWWG TADIMIGFAR GAHGDSYPFD GPGNTI AHAF 180 APGTGLGGDA HFDEDERWTD GSSLGINFLY AATHELGHSL GMGHSSDPNA VMYPTYGNGD 240 PQNFKLSQDD IKGIQKLYGK RSNSRKK
Seq ID NO : 623 DNA sequence
Nucleic Acid Accession # : NM.031457.1
Coding sequence : 204. .956
11 21 31 41 51
AAACAGGAAA TAAATACGAA TGAAACTβAβ CTCTAAGCAβ CATGTAACCT GGCCTGCATC 60 CAGGAAATAG AGGACTTCGβ ATCCTTCTAA CCCTACCACC CAACTGGCCC CAGTACATTC 120 ATTCTCTCAG GAAAAAAAAC AAGGTCCCCA CAGCAAAGAA AAGGAATAGG ATCAAGAGAT 180 ACGTGGCTGC TGGCAGAGCA AβCATGAATT CGAT6ACTTC AGCAβTTCCG GTGGCCAATT 240 CTGTGTTGGT GGTGGCACCC CACAATGGTT ATCCTGTGAC CCCAGGAATT ATGTCTCACG 300 TGCCCCTGTA TCCAAACAGC CAGCCGCAAG TCCACCTAGT TCCTGGGAAC CCACCTAGTT 360 TGGTGTCβAA TGTGAATGGG CAGCCTGTGC AGAAAGCTCT GAAAGAAGGC AAAACCTTGG 420 βGGCCATCCA GATCATCATT GGCCTGGCTC ACATCGGCCT CGGCTCCATC ATGGCGACGG 480 TTCTCGTAGG GGAATACCTG TCTATTTCAT TCTACGGAGG CTTTCCCTTC TGGGGAGGCT 540 TGTGGTTTAT CATTTCAGGA TCTCTCTCCG TGGCAGCAGA AAATCAGCCA TATTCTTATT 600 GCCTβCTGTC TGGCAGTTTG GGCTTGAACA TCGTCAGTGC AATCTGCTCT GCAGTTGGAG 660 TCATACTCTT CATCACAGAT CTAAGTATTC CCCACCCATA TGCCTACCCC GACTATTATC 720 CTTACGCCTG GGGTGTGAAC CCTGGAATGG CGATTTCTGG CGTGCTGCTG GTCTTCTGCC 780 TCCTGGAGTT TGGCATCGCA TGCGCATCTT CCCACTTTββ CTGCCAGTTG GTCTGCTGTC 840 AATCAAGCAA TGTGAGTGTC ATCTATCCAA ACATCTATCC AGCAAACCCA GTGATCACCC 900 CAGAACCGGT βACCTCACCA CCAAGTTATT CCAGTGAGAT CCAAGCAAAT AAGTAAGGCT 960 ACAGATTCTG GAAGCATCTT TCACTGGGAC CAAAAGAAGT CCTCCTCCCT TTCTGGGCTT 1020 CCATAACCCA GGTCGTTCCT GTTCTGACAG CTGAGGAAAC GTCTCTCCCA CTGTTTGTAC 1080 TCTCACCTTC ATTCTTCAAT TCAGTCTAGG AAACCATGCT GTTTCTCTAT CAAGAAGAAG 1140 ACAGAGATTT TAAACAGATG TTAACCAAGA GβGACTCCCT AGGGCACATG CATCAGCACA 1200 TATGTGGGCA TCCAGCCTCT GβGGCCTTGG CACACACACA TTCβTGTGCT CTGCTGCATβ 1260 TGAGCTTGTG GGTTAGAGGA ACAAATATCT AGACATTCAA TCTTCACTCT TTCAATTGTG 1320 CATTCATTTA ATAAATAGAT ACTGAGCATT CAAAAAAAAA AAAAAAAAA
Seq ID NO: 624 Protein sequence D Protein Accession ft: NP_113645.1
1 11 21 31 41 51
I I I I I I
MNSMTSAVPV ANSVLWAPH NGYPVTPGIM SHVPLYPNSQ PQVHLVPGNP PSLVSNVNGQ 60
10 PVQKALKEGK TLGAIQIIIG LAHIGLGSIM ATVLVGEYLS ISFYGGFPFW GGLWFIISGS 120
LSVAAENQPY SYCLLSGSLG LNIVSAICSA VGVILFITDL SIPHPYAYPD YYPYAWβVNP 180
GMAISGVLLV FCLLEFGIAC ASSHFGCQLV CCQSSNVSVI YPNIYAANPV ITPEPVTSPP 240 SYSSEIQANK
15 Seq ID NO: 625 DNA sequence
Nucleic Acid Accesεion #: NM_005221.3
Coding sequence: 1..870
_. 1 11 21 31 41 51
20 i i i i i i
ATGACAGGAG TGTTTGACAG AAGGGTCCCC AGCATCCGAT CCGGCGACTT CCAAGCTCCG 60
TTCCAGACGT CCGCAβCTAT GCACCATCCG TCTCAGGAAT CGCCAACTTT GCCCGAGTCT 120
TCAGCTACCG ATTCTGACTA CTACAGCCCT ACGGGβeβAβ CCCCGCACGG CTACTGCTCT 180
CCTACCTCGβ CTTCCTATGG CAAAGCTCTC AACCCCTACC AGTATCAGTA TCACGGCβTG 240
25 AACGGCTCCe CCGGGAGCTA CCCAGCCAAA GCTTATGCCG ACTATAGCTA CGCTAGCTCC 300
TACCACCAGT ACGGCGGCGC CTACAACCGC GTCCCAAGCG CCACCAACCA GCCAGAGAAA 360
GAAGTGACCG AGCCCGAGGT GAGAATβGTG AATGGCAAAC CAAAGAAAGT TCGTAAACCC 420
AGGACTATTT ATTCCAGCTT TCAGCTGβCC βCATTACAGA GAAGGTTTCA GAAGACTCAG 480
TACCTCGCCT TGCCGGAACG CGCCGAGCTG GCCGCCTCGC TGGGATTGAC ACAAACACAG 540
30 GTGAAAATCT GGTTTCAβAA CAAAAGATCC AAGATCAAGA AGATCATGAA AAACGGGGAG 600
ATGCCCCCGG AGCACAGTCC CAGCTCCAGC GACCCAATGG C6TGTAACTC GCCGCAGTCT 660
CCAGCGGTGT GββAGCCCCA GGGCTCGTCC CCCTCGCTCA GCCACCACCC TCATGCCCAC 720
CCTCCGACCT CCAACCAGTC CCCAGCGTCC AGCTACCTGG AGAACTCTGC ATCCTGGTAC 780
ACAAGTGCAG CCAGCTCAAT CAATTCCCAC CTGCCβCCβC CGGGCTCCTT ACAGCACCCG 840
35 CTGβCGCTGG CCTCCGβGAC ACTCTATTAG
Seq ID NO: 626 Protein sequence Protein Accession ft: NP_005212.1
40 1 11 21 31 41 51
I I I I I I
MTGVFDRRVP SIRSβDFQAP FQTSAAMHHP SQESPTLPES SATDSDYYSP TGGAPHGYCS 60
PTSASYGKAL NPYQYQYHGV NGSAGSYPAK AYADYSYASS YHQYGGAYNR VPSATNQPEK 120
EVTEPEVRMV NGKPKKVRKP RTIYSSFQLA ALQRRFQKTQ YLALPERAEL AASLGLTQTQ 180
45 VKIWFQNKRS KIKKIMKNGE MPPEHSPSSS DPMACNSPQS PAVWEPQGSS RSLSHHPHAH 240 PPTSNQSPAS SYLENSASWY TSAASSINSH LPPPGSLQHP LALASGTLY
Seq ID NO: 627 DNA sequence Nucleic Acid Accession ft: NM_014420
50 Coding sequence: 118..792
1 11 21 31 41 51
I I I I I I
GCACGAGAGA CGACGTGCTG AGCTGCCAGC TTAGTGGAAG CTCTGCTCTG GGTGGAGAGC 60
55 AGCCTCGCTT TGβTGACGCA CAGTGCTGGG ACCCTCCAGG AGCCCCGGGA TTGAAβGATG 120
GTGGCGGCCG TCCTGCTGGG GCTGAGCTGG CTCTGCTCTG CCCTGGGAGC TCTGβTCCTG 180
GACTTCAACA ACATCAGGAG CTCTGCTGAC CTGCATGGGG CCCGGAAGGG CTCACAGTGC 240
CTGTCTGACA CGGACTGCAA TACCAGAAAG TTCTGCCTCC AGCCCCGCGA TGAβAAβCCG 300
TTCTGTGCTA CATGTCGTGG GTTGCββAGG AGGTGCCAGC GAGATGCCAT GTGCTGCCCT 360
60 GGGACACTCT GTGTGAACGA TGTTTGTACT ACGATGGAAG ATGCAACCCC AATATTAGAA 420
AGGCAGCTTG ATGAGCAAGA TGGCACACAT GCAGAAGGAA CAACTGGGCA CCCAGTCCAG 480
GAAAACCAAC CCAAAAGGAA GCCAAGTATT AAGAAATCAC AAGGCAGGAA GGGACAAGAG 540
GGAGAAAGTT GTCTGAGAAC TTTTGACTCT GGCCCTGGAC TTTGCTGTGC TCGTCATTTT 600
TGGACGAAAA TTTβTAAGCC AGTCCTTTTG GAGGGACAGG TCTGCTCCAG AAGAβGGCAT 660
65 AAAGACACTG CTCAAGCTCC AGAAATCTTC CAGCGTTGCβ ACTGTGGCCC TGGACTACTG 720
TβTCGAAGCC AATTGACCAG CAATCGGCAG CATGCTCGAT TAAGAGTATG CCAAAAAATA 780
GAAAAGCTAT AAATATTTCA AAATAAAGAA GAATCCACAT TGCAAAAAAA AAAAAAAAAA 840 A
70 Seq ID NO: 628 Protein sequence Protein Accession ft: NP_055235
1 11 21 31 41 51
I I I I I I
75 MVAAVLLGLS WLCSPLGALV LDFNNIRSSA DLHGARKGSQ CLSDTDCNTR KFCLQPRDEK 60
PFCATCRGLR RRCQRDAMCC PGTLCVNDVC TTMEDATPIL ERQLDEQDGT HAEGTTGHPV 120
QENQPKRKPS IKKSQGRKGQ EGESCLRTFD CGPGLCCARH FWTKICKPVL LEGQVCSRRG 180 HKDTAQAPEI FQRCDCGPGL LCRSQLTSNR QHARLRVCQK IEKL
80 Seq ID NO: 629 DNA sequence
Nucleic Acid Accession ft: NM_002448.1
Coding sequence: 241..1134
11 21 31 eCβCGAGTGC TCCCGGGAAC TCTGCCTGCG CGGCGGCAGC GACCGGAGGC CAGGCCCAGC 60 ACGCCβGAGC TGGCCTGCTG GβGAGGββCG GGAGGCGCGC CCGGGAGGGT CCGCCCGGCC 120 AGGCCCCGGG CCCTCGCAGA GGCCGβCCβC GCTCCCAβCC CGCCCGGAGC CCATGCCCGG 180 CGGCTGGCCA GTGCTGCGGC AGAAGGGGGG GCCCGGCTCT GCATGGCCCC GGCTGCTGAC 240 ATGACTTCTT TGCCACTCGG TGTCAAAβTβ GAGGACTCCG CCTTCGGCAA GCC6GCGGGG 300 GGAGGCβCGG GCCAGGCCCC CAGCGCCGCC GCGGCCACGG CAGCCβCCAT GGGCβCGβAC 360 GAGGAGGGGG CCAAGCCCAA AGTGTCCCCT TCGCTCCTGC CCTTCAGCGT GβAGGCGCTC 420 ATGGCCGACC ACAGGAAGCC GGGGGCCAAG GAGAGCGCCC TGGCGCCCTC CGAGβGCGTG 480 CAGGCGGCGG GTGGCTCGGC GCAGCCACTG GGCGTCCCGC CGGGGTCGCT GGβAβCCCCG 540 GACGCGCCCT CTTCGCCGCG GCCGCTCGβC CATTTCTCGG TGGGββGACT CCTCAAGCTG 600 CCAGAAGATG CGCTCGTCAA AβCCGAGAGC CCCGAGAAGC CCGAβAβGAC CCCGTGGATG 660 CAGAGCCCCC GCTTCTCCCC CCCβCCGGCC AGGCGGCTGA GCCCCCCAGC CTGCACCCTC 720 CGCAAACACA AGACGAACCG TAAGCCGCGG ACGCCCTTCA CCACCGCGCA GCTGCTGGCG 780 CTGGAGCGCA AGTTCCGCCA GAAβCAGTAC CTGTCCATCG CCGAGCβCβC GGAGTTCTCC 840 AGCTCβCTCA GCCTCACTGA GACGCAGβTβ AAGATATGGT TCCAGAACCG CCGCGCCAAG 900 GCAAAGAGAC TACAAGAGGC AGAGCTGGAG AAGCTGAAGA TGGCCeCCAA GCCCATGCTG 960 CCACCGGCTG ccTTCβeccT CTCCTTCCCT CTCGGCGGCC CCGCAGCTGT. AGCGGCCGCC 1020 GCGGGTGCCT CGCTCTACGβ TGCCTCTGβC CCCTTCCAGC GCGCCGCGCT GCCTGTGGCG 1080 CCCGTGGGAC TCTACACGGC CCATGTGGGC TACAGCATGT ACCACCTGAC ATAGAGGGTC 1140 CCAGGTCCCC ACCTGTGGGC CAGCCGATTC CTCCAGCCCT GGTGCTGTAC CCCCGACGTG 1200 CTCCCCTGCT CGGCACCGCC AGCCGCCTTC CCTTTAACCC TCACACTGCT CCAGTTTCAC 1260 CTCTTTGCTC CCTGAGTTCA CTCTCCGAAβ TCTGATCCCT GCCAAAAAGT GGCTGGAAGA 1320 GTCCCTTAGT ACTCTTCTAG CATTTAGATC TACACTCTCG AGTTAAAGAT GGGGAAACTG 1380 AGGGCAGAGA GGTTAACAGA TTTATCTAGG GTCCCCAGCA GAATTGACAG TTGAACAGAG 1440 CTAGAGGCCA TGTCTCCTGC ATAGCTTTTC CCTGTCCTGA CACCAGGCAA GAAAAGCGCA 1500 GAGAAATCGG TGTCTGACGA TTTTGGAAAT GAGAACAATC TCAAAAAAAA AAAAAAAAAA 1560 AAAAAAAAAA GAAAAGAGAA AAAAAAGACT AGCCAGCCAG GAAGATGAAT CCTAGCTTCT 1620 TCCATTG6AA AATTTAAGAC AAGTTCAACA ACAAAACATT TβCTCTβGGG GGCAGGGAAA 1680 ACACAβATβT GTTGCAAAGG TAGGTTGAAG GGA
Seq ID NO: 630 Protein sequence Protein Accession ft: NP 002439.1
11 21 31 41 51
I I I I I
MTSLPLGVKV EDSAFGKPAG GGAGQAPSAA AATAAAMGAD EEGAKPKVSP SLLPFSVEAL 60 MADHRKP6AK ESALAPSEGV QAAGGSAQPL GVPPGSLGAP DAPSSPRPLG HFSVGGLLKL 120 PEDALVKAES PEKPERTPWM QSPRFSPPPA RRLSPPACTL RKHKTNRKPR TPFTTAQLLA 180 LERKFRQKQY LSIAERAEFS SSLSLTETQV KIWFQNRRAK AKRLQEAELE KLKMAAKPML 240 PPAAF6LSFP LGGPAAVAAA AGASLYGASβ PFQRAALPVA PVGLYTAHVG YSMYHLT
Seq ID NO: 631 DNA sequence
Nucleic Acid Accession if: NM_002557.1
Coding sequence: 13..2049
11 21 31 41 51
I I I I I
CAGACCATTC AGATGTGGAA GCTβTTGCTG TGGGTTGGGC TGGTTCTTGT GCTGAAACAC 60 CACβATββTG CTGCCCATAA ACTCGTGTGT TATTTCACCA ACTGGGCACA CAGTCGGCCA 120 GGCCCTGCCT CGATCTTGCC CCATGACCTG GACCCCTTTC TCTGCACCCA CCTGATATTT 180 GCCTTTGCCT CAATGAACAA CAATCACATT GTTGCTAAGG ATCTCCAGGA TGAGAAAATT 240 CTCTACCCAG AGTTCAACAA ACTAAAGGAG AGGAACAGAG AGCTGAAAAC ACTACTGTCC 300 ATCGGCGGGT GGAACTTTGG CACCTCAAGA TTCACCACTA TGTTGTCCAC ATTTGCCAAC 360 CGTGAAAAGT TTATTGCTTC AGTTATATCC CTTCTGAGGA CACATGACTT TGATGCTCTT 420 GACCTTTTCT TCTTATATCC TGGACTAAGA GGCAGCCCCA TGCATGACCG GTGGACTTTT 480 CTCTTCTTAA TTGAAGAβCT CCTGTTTGCC TTCCGGAAGG AGGCACTGCT CACCATGCGC 540 CCGAGGCTGC TGCTGTCTGC TGCTGTTTCT GGGGTCCCAC ACATCGTCCA AACATCCTAT 600 GATGTGCGCT TTCTAGGAAG ACTCCTGGAT TTCATCAATG TCTTGTCTTA T6ACTTACAT 660 GGAAGTTGGG AAAGGTTCAC AGGACATAAT AGCCCCCTCT TCTCTCTGCC TβAAGACCCC 720 AAATCTTCGβ CATATGCTAT GAATTATTGG AGAAAGCTTβ GGGCACCCTC AGAGAAGCTC 780 ATCATGGGGA TCCCCACCTA TGGACGTACC TTTCGCCTCC TCAAAGCCTC TAAGAATGGG 840 TTGCAGGCCA GAGCGATCGG ACCAGCATCT CCAGGGAAGT ACACCAAGCA AGAAGGCTTC 900 TTGGCTTATT TTGAGATTTG TTCCTTTGTC TGGGGAGCGA AGAAGCACTG GATTGATTAC 960 CAGTATβTCC CGTATGCCAA CAAGGGGAAA GAGTGGGTTG GCTATGACAA TGCCATCAGC 1020 TTCAβTTACA AGGCATGGTT TATAAGβCGA GAGCATTTTG GGGGGGCCAT GGTβTGGACA 1080 TTGGACATGG ATGACGTCAG GGGCACGTTC TGTGGCACTβ GCCCTTTCCC CCTTGTCTAC 1140 GTATTGAATG ATATCCTGGT GCGGGCTGAG TTCAGTTCAA CTTCTTTACC ACAATTTTGG 1200 CTGTCATCTG CTGTGAATTC TTCAAGCACT GACCCTGAAA GGCTGGCTGT GACCACGGCA 1260 TGGACCACTG ATAGTAAGAT TTTGCCCCCA βGAGGAGAGG CTGGGβTCAC TGAGATCCAC 1320 GGAAAGTGTG AAAATATGAC TATAACCCCT AGAGGTACAA CTGTGACCCC TACAAAGGAA 1380 ACTGTATCCC TTGGAAAGCA CACTGTAGCT CTAGGAGAGA AGACTGAGAT CACTGGGGCA 1440 ATGACCATGA CTTCTGT6GG TCATCAGTCC ATGACCCCTG GAGAGAAGGC CCTGACCCCT 1500 GTGGGTCATC AATCTGTGAC CACTGGACAG AAGACCCTGA CCTCTGTGGG TTATCAGTCT 1560 GTGACCCCTG CβGAAAAGAC CCTGACCCCT GTGGGTCATC AGTCTGTGAC CCCTGTGAGT 1620 CATCAGTCTG TGAGCCCTGG AGGAACGACT ATGACCCCTG TCCATTTTCA GACTGAGACC 1680 CTTAGACAGA ATACAGTGGC CCCTAGAAGG AAGGCTGTGG CCCGTGAAAA GGTGACTGTC 1740 CCCTCCAGAA ACATATCAGT CACCCCTGAA GGGCAGACTA TGCCTTTAAG AGGGGAGAAT 1800 TTGACTTCTG AGGTGGGCAC TCACCCCAGG ATGGGTAACT TGGGTCTTCA GATGGAAGCT 1860 GAAAACAGGA TGATGCTGTC CTCCAGCCCC GTCATCCAGC TCCCGGAACA AACTCCTCTA 1920 GCTTTTGACA ACCGCTTTβT TCCCATCTAT GGAAACCATT CCTCTGTCAA CTCAGTAACC 1980 CCTCAAACAA GTCCTCTTTC TCTAAAAAAA GAAATCCCAG AAAACTCTGC TGTGGATGAA 2040 GAAGCCTAAG CCCCTCTGGT GTCAGAAACC AGGGAAAACC CTTβTCTTTT CTTCTAAGTG 2100 ACATGTTGGA AGCCTTCTCA TCCCGGGGCA AAGCAGGCAT CAAAACCAβA ATAGGCCAAT 2160 CTCTTTTCCA TTAAATAAAC TGTAAACACA AGAACCCA
Seq ID NO: 632 Protein sequence Protein Accession ft: NP_002548.1
1 11 21 31 41 51
M IWKLLLWVGL VILVLKHHDGA AIHKLVCYFTN WIAHSRPGPAS IILPHDLDPFL CITHLIFAFAS 60
MNNNQIVAKD LQDEKILYPE FNKLKERNRE LKTLLSIGGW NFGTSRFTTM LSTFANREKF 120
IASVISLLRT HDFDGLDLFF LYPGLRGSPM HDRWTFLFLI EELLFAFRKE ALLTMRPRLL 180
LSAAVSGVPH IVQTSYDVRF LGRLLDFINV LSYDLHGSWE RFTGHNSPLF SLPEDPKSSA 240
YAMNYWRKLG APSEKLIMGI PTYGRTFRLL KASKNGLQAR AlβPASPGKY TKQEGFLAYF 300
EICSFVWβAK KHWIDYQYVP YANKGKEWVG YDNAISFSYK AWFIRREHFG GAMVWTLDMD 360
DVRGTFCGTG PFPLVYVLND ILVRAEFSST SLPQFWLSSA VNSSSTDPER LAVTTAWTTD 420
SKILPPGGEA GVTEIHGKCE NMTITPRGTT VTPTKETVSL GKHTVALGEK TEITGAMTMT 480
SVGHQSMTPG EKALTPVGHQ SVTTGQKTLT SVGYQSVTPG EKTLTPVGHQ SVTPVSHQSV 540
SPGGTTMTPV HFQTETLRQN TVAPRRKAVA REKVTVPSRN ISVTPEGQTM PLRβENLTSE 600
VβTHPRMGNL GLQMEAENRM MLSSSPVIQL PEQTPLAFDN RFVPIYβNHS SVNSVTPQTS 660 PLSLKKEIPE NSAVDEEA
Seq ID NO: 633 DNA sequence
Nucleic Acid Accession ft: NM_003885.1
Coding sequence: 98..1021
1 11 21 31 41 51
I I I I I I
AAACTCAβAA TTTTCGCGGG CTCGGTGAGC GGTTTTATCC CTCCGGCCGβ CAGGCTGGβC 60
GCAGGGGGCC AGCCCCCGCC CGGCGCGCAG CAGCACCATG GGCACGGTGC TGTCCCTGTC 120
TCCCAGCTAC CGGAAGGCCA CGCTGTTTGA G6ATGGCGCG GCCACCGTGG GCCACTATAC 180 eβCCGTACAG AACAGCAAGA ACGCCAAGGA CAACAACCTG AAGCGCCACT CCATCATCTC 240
CGTGCTGCCT TGGAAGAGAA TCGTGGCCGT GTCGGCCAAG AAGAAβAACT CCAA6AAGGT 300
GGAGGCTAAC AGCAGCTACC AGAACAACAT CACGCACCTC AACAATGAGA ACCTGAAGAA 360
GTCGCTGTCG TGCGCCAACC TGTCCACATT CGCCCAGCCC CCACCGGCCC AGCCGCCTGC 420
ACCCCCGGCC AGCCAGCTCT CGGGTTCCCA GACCGGGGGC TCCTGCTCAG TCAAGAAAGC 480
CCCTCACCCT GCCGTCACCT CCGCAGGGAC GCCCAAACGG GTCATCGTCC AGGCGTCCAC 540
CAGTGAGCTG CTTCGCTGCC TGGGTGAGTT TCTCTGCCGC CGGTGCTACC GCCTGAAGCA 600
CCTGTCCCCC ACGGACCCCG TGCTCTGGCT GCGCAGCGTG GACCGCTCGC TGCTTCTGCA 660
GGGCTGGCAG GACCAGGGCT TCATCACGCC GGCCAACGTG GTCTTCCTCT ACATGCTCTG 720
CAGGGATGTT ATCTCCTCCG AGGTGGGCTC GGATCACGAG CTCCAGGCCG TCCTGCTGAC 780
ATGCCTGTAC CTCTCCTACT CCTACATGGG CAACβAGATC TCCTACCCGC TCAAGCCCTT 840
CCTGGTGGAβ AGCTGCAAGβ AGGCCTTTTG GGACCGTTGC CTCTCTGTCA TCAACCTCAT 900
GA6CTCAAAG ATGCTGGAGA TAAATGCCGA CCCACACTAC TTCACACAGG TCTTCTCCGA 960
CCTGAAGAAC GAGAGCGGCC AGGAGGACAA GAAGCGGCTC CTCCTAGGCC TGGATCGGTG 1020
AGCACTGTAG CCTGCGTCAT GGCTCAAGGA TTCAATGCAT TTTTAAGAAT TTATTATTAA 1080 ATCAGTTTTG TGTACAG
Seq ID NO: 634 Protein sequence Protein Accession ft: NP_003876.1
1 11 21 31 41 51
M IGTVLSLSPS YIRKATLFEDG AIATVGHYTAV QINSKNAKDKN LIKRHSIISVL PIWKRIVAVSA 60
KKKNSKKVQP NSSYQNNITH LNNENLKKSL SCANLSTFAQ PPPAQPPAPP ASQLSGSQTG 120
GSSSVKKAPH PAVTSAGTPK RVIVQASTSE LLRCLGEFLC RRCYRLKHLS PTDPVLWLRS 180
VDRSLLLQGW QDQGFITPAN WFLYMLCRD VISSEVGSDH ELQAVLLTCL YLSYSYMGNE 240
ISYPLKPFLV ESCKEAFWDR CLSVINLMΞS KMLQINADPH YFTQVFSDLK NESGQEDKKR 300 LLLGLDR
TABLE 79A
Pkey Unique Eos probeset identifier number
ExAccn Exemplar Accession number, Genbank accession number
UnigenelD Unigene number
Unigene Title Unigene gene title
Seq ID No Sequence identification number linking information in Table 79A to sequences in Table 80
Pkey ExAccn UnigenelD Unigene Title Seq ID No
424212 NM 005814 Hs 143131 glycoprotein A33 (transmembrane) Seq ID No C1&C217
424503 NM 002205 Hs 149609 integπn, alpha 5 (fibronectin receptor, Seq ID No C2&C218
418007 M13509 Hs 83169 matnx metalloprotemase 1 (interstitial Seq ID No C3&C219
418007 M13509 Hs 83169 matnx metalloproteinase 1 (interstitial Seq ID No C4.C220
418738 AW388633 Hs6682 solute earner family 7, (cationic ammo Seq ID No C5&C221
443646 AI085198 Hs 164226 Thrombospondm 1 Seq ID No C6&C222
409956 AW103364 Hs727 inhibin, beta A (activin A, activin AB a Seq ID No C7&C223
422867 L32137 Hs1584 cartilage oligomeπc matnx protein (pse Seq ID No C8&C224
444381 BE387335 Hs 283713 hypothetical protein BC014245 Seq ID No C9&C225
421582 AI910275 Hs 350470 trefoil factor 1 (breast cancer, estroge Seq ID No C10&C226
411789 AF245505 Hs 72157 Adlican Seq ID No C11&C227
452281 T93500 Hs 28792 Homo sapiens cDNA FU11041 fis, clone PL Seq ID No C12
428698 AA852773 Hs 334838 KIAA1866 protein Seq ID No C13&C228
421552 AF026692 Hs 105700 secreted fπzzled related protein 4 SeqlDNo C14&C229
425247 NM 005940 Hs 155324 matnx metalloprotemase 11 (stromelysin Seq ID No C15&C230
432201 AI538613 Hs 298241 Transmembrane protease, seπne 3 Seq ID No C16 & C231
447377 X77343 Hs 334334 transcnption factor AP-2 alpha Seq ID No C17&C232
446921 AB012113 Hs 16530 small inducible cytokine subfamily A (Cy Seq ID No C18&C233
418888 AU076801 Hs 89436 cadhenn 17, Ll cadhenn (liver-intestin Seq ID No C19&C234
432179 X75208 Hs 2913 EphB3 Seq ID No C20&C235
422578 AF239666 Hs 1545 caudal type homeo box transcnption fact Seq ID No C218, C236
409889 AW630041 Hs 56937 suppression of tumoπgenicily 14 (colon Seq ID No C22&C237
447033 AI357412 Hs 157601 Predicted gene Eos cloned, secreted w/V Seq ID No C23&C238
447033 AI357412 Hs 157601 Predicted gene Eos cloned, secreted w/V Seq ID No C24&C239
411975 AI916058 Hs 144583 3'UTRof dead πnger (Drosophιla)-lιke Seq ID No C25&C240
434206 AW136973 Hs 362915 ESTs, Weakly similarto S69890 mitogen i Seq ID No C26&C241
423936 U77629 Hs 135639 achaete scute complex (Drosophila) homol Seq ID No C27.C242
447400 AK000322 Hs 18457 hypothetical protein FLJ20315 Seq ID No C28&C243
449032 AA045573 Hs 22900 nuclear fxtor (erythroid deπved 2) lik Seq ID No C29&C244
415214 AI445236 Hs 125124 EphB2 Seq ID No C30&C245
443247 BE614387 Hs 333893 c Myc target JPOI Seq ID No C3UC246
422048 NM 012445 Hs 288126 spondiπ 2, extracellular matnx protein Seq ID No C32.C247
410418 D31382 Hs 63325 transmembrane protease, senne 4 Seq ID No C33&C248
446342 BE298665 Hs 14846 solute earner family 7 (cationic ammo Seq ID No C34&C249
411274 NM 002776 Hs 69423 kallikrein 10 Seq ID No C35&C250
104978 AI199268 Hs 19322 Homo εapiens, Similar to RIKEN cDNA 2010 Seq ID No C36&C251
422260 AA315993 Hs 105484 regenerating gene fype IV Seq ID No C37&C252
409041 AB033025 Hs 50081 Hypothetical protein, XP.051860 (KIAA119 Seq ID No C38 & C253
420344 BE463721 Hs 97101 putative G protein-coupled receptor Seq ID No C39&C254
422163 AF027208 Hs 112360 prominin (mouse)-lιke 1 Seq ID No C40&C255
437935 AW939591 Hs5940 mucin 13, epithelial transmembrane Seq ID No C41 & C256
422330 D30783 Hs 115263 epiregulin Seq ID No C42&C257
408908 BE296227 Hs 250822 seπne/threonme kinase 15 Seq ID No C43&C258
407811 AW190902 Hs 40098 cysteine knot superfamily 1, BMP antagon Seq ID No C44&C259
437852 BE001836 Hs 256897 putative GPCR Seq ID No C45&C260
408243 Y00787 Hs624 interleukin 8 Seq ID No C46&C261
426088 AF038007 Hs 166196 ATPase, Class I, type 8B, member 1 SeqlDNo C47&C262
439738 BE246502 Hs9598 sema domain, immunoglobulin domain (Ig), Seq ID No C48.C263
419741 NM.007019 Hs 93002 ubiquitin earner protein E2-C Seq ID No C49&C264
450983 AA305384 Hs 25740 ER01 (S cerevιsιae)-lιke Seq ID No C50&C265
417771 AA804698 Hs 82547 retinoic acid receptor responder (tazaro Seq ID No C51&C266
421379 Y15221 Hs 103982 small inducible cytokine subfamily B (Cy Seq ID No C52&C267
442006 AW975183 Hs 372210 ESTs, Weakly similar to S72482 hypotheti Seq ID No C53&C268
413048 M93221 Hs 75182 mannose receptor, C type 1 Seq ID No C54&C269
443324 R44013 Hs 164225 ESTs Seq ID No C55&C270
424917 AI636208 Hs 96901 hypothetical protein FLJ23049 Seq ID No C56&C271
424917 AI636208 Hs 96901 hypothetical protein FU23049 Seq ID No C57&C272
444527 NM 005408 Hs 11383 small inducible cytokine subfamily A (Cy Seq ID No C58&C273
442652 AI005163 Hs 201378 Homo sapiens cDNA FU40427 fis Seq ID No C59&C274
450726 AW204600 Hs 355462 HUMPSPBA Human pulmonary surfactant-asso Seq ID No C60&C275
416965 N26223 Hs 160436 MDAC1 Seq ID No C61 & C276
442275 AW449467 Hs 54795 Homo sapiens secretoglobm, family 3A Seq ID No C62&C277
431745 AW972448 Hs 163425 Novel FGENESH predicted cadhenn repeat Seq ID No C63&C278
431745 AW972448 Hs 163425 Novel FGENESH predicted cadhenn repeat Seq ID No C64&C279
453142 AA033648 Hs 473 Homo sapiens gap junction protein, alpha Seq ID No C65 & C280
421659 NM 014459 Hs 106511 protocadhenn 17 Seq ID No C66&C281
444090 S69115 Hs 10306 natural killer cell group 7 sequence Seq ID No C67&C282
421563 NM.006433 Hs 105806 granulysm Seq ID No C68&C283
430413 AW842182 Hs 241392 small inducible cytokine A5 (RANTES) Seq ID No C69&C284
414991 C17898 Homo sapiens up-regulated by BCG-CWS (LO Seq ID No C70 & C285
419833 AA251131 Hs 220697 Homo sapiens tryptophanyl tRNA synthetas Seq ID No C71 & C286
424943 AU077260 Hs 153924 death associated protein kinase 1 Seq ID No C72&C287 430890 X54232 Hs.2699 glypican 1 SeqlD o.C738.C288
452401 NM 007115 Hs.29352 tumor necrosis factor, alpha-induced pro Seq ID No. C74 & C289
439180 AI393742 Hs.199067 v-erb-b2 avian erythroblastic leukemia v SeqlDNo.C75&C290
410407 X66839 Hs.63287 carbonic anhydrase IX SeqlDNo.C768.C291
418526 BE019020 Hs.85838 solute earner family 16 (monocarboxylic Seq ID No. C77 & C292
422627 BE336857 Hs.118787 transforming growth factor, beta-induced Seq ID No. C78 & C293
430486 BE062109 Hs.241551 chloride channel, calcium activated, fam Seq ID No. C79 & C294
423673 BE003054 Hs.1695 matrix metalloproteinase 12 (macrophage Seq ID No. C80 & C295
423673 BE003054 Hs.1695 matrix metalloproteinase 12 (macrophage Seq ID No. C81 & C296
431846 BE019924 Hs.271580 uroplakin 1B Seq ID No. C82 _ C297
431958 X63629 Hs.2877 cadherin 3, type 1, P-cadherin (placenta SeqlDNo.C838.C298
448733 NM 005629 Hs.187958 solute camerfamily 6 (neurotransmitte SeqlDNo.C84&C299
426440 BE382756 Hs.169902 solute earner family 2 (facilitated glu SeqlDNo.C858.C300
428484 AF104032 Hs.184601 solute carrier family 7 (cationic amino Seq ID No. C86 & C301
429211 AF052693 Hs.198249 gap junction protein, beta 5 (connexin 3 SeqlDNo.C87&C302
423634 AW959908 Hs.1690 heparin-binding growth factor binding pr SeqlDNo.C88S.C303
457819 AA057484 Hs.35406 FLJ20522 Hypothetical protein FLJ20522 SeqlDNo.C89&C304
424687 J05070 Hs.151738 matrix metalloproteinase 9 (gelatinase B SeqlDNo.C90&C305
418462 BE001596 Hs.85266 integrin, beta 4 Seq ID No. C91 & C306
439606 W79123 Hs.58561 G protein-coupled receptor 87 SeqlD o.C92&C307
407720 AB037776 Hs.38002 immunoglobulin superfamily, member 9 SeqlDNo.C93&C308
418543 NM 005329 Hs.85962 hyaluronaπ synthase 3 SeqlDNo.C94&C309
417512 X76534 Hs.82226 glycoprotein (transmembrane) nmb SeqlDNo.C95&C310
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C96&C311
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C97&C312
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C98S.C313
415817 U88967 Hs.78867 protein tyrasine phosphatase, receptor-t SeqlDNo.C99&C314
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C100&C315
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C10UC316
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C1028.C3l7
415817 U88967 Hs.78867 protein tyrosine phosphatase, receptor-t SeqlDNo.C103.C318
421817 AF146074 Hs.108660 ATP-binding cassette, sub-family C (CFTR SeqlDNo.C1048.C319
421817 AF146074 Hs.108660 ATP-binding cassette, sub-family C (CFTR SeqlD o.C1058.C320
409420 Z15008 Hs.54451 laminin, gamma 2 (nicein (100kD), kalini SeqlDNo.C1068.C321
440659 AF134160 Hs.7327 claudin 1 Seq ID No. C1078. C322
408790 AW580227 Hs.47860 neurotrophic tyrosine kinase, receptor, SeqlDNo.C1088.C323
408790 AW580227 Hs.47860 neurotrophic tyrosine kinase, receptor, Seq ID No. C1098. C324
408790 AW580227 Hs.47860 neurotrophic tyrosine kinase, receptor, SeqlDNo.C1108.C325
450701 H39960 Hs.288467 hypothetical protein XP.098151 (leucine- SeqlDNo.C1118.C326
414774 X02419 Hs.77274 piasminogen activator, urokinase SeqlDNo. C112&C327
413691 AB023173 Hs.75478 ATPase, Class VI, type 11B SeqlDNo.C1138.C328
453857 AL080235 Hs.35861 Ras-induced senescence 1 (RIS1) SeqlDNo.C1148.C329
449101 AA205847 Hs.23016 G protein-coupled receptor SeqlDNo.C1158.C330
429263 AA019004 Hs.198396 ATP-binding cassette, sub-family A (ABC1 SeqlDNo.C1168.C331
421474 U76362 Hs.104637 solute earner family 1 (glutamate trans .SeqlDNo.C1178.C332
421753 BE314828 Hs.107911 ATP-binding cassette, sub-family B (MDR/ SeqlDNo.C1188.C333
408482 NM.000676 Hs.45743 adeπosiπe A2b receptor SeqlDNo.C1198.C334
426761 AI015709 Hs.172089 PORIMIN Pro-oncos'ts receptor inducing me SeqlDNo.C1208.C335
429736 AF125304 Hs.212680 tumor necrosis factor receptor superfami SeqlDNo.C1218.C336
430985 AA490232 Hs.27323 ESTs, Weakly similar to 178885 serine/th SeqlDNo.C122S.C337
431890 X17033 Hs.271986 integrin, alpha 2 (CD49B, alpha 2 subuni SeqlDNo.C1238.C338
432583 AW023624 Hs.162282 potassium channel TASK-4; potassium chan Se lDNo.C124S.C339
446872 X97058 Hs.16362 pyrimidinergic receptor P2Y, G-protein e SeqlDNo.C1258.C340
453102 NM 007197 Hs.31664 frizzled (Drosophila) homolog 10 SeqlDNo.C1268.C341
428513 BE220806 Hs.184697 plexin C1 Se lDNo.C1278.C342
430280 AA361258 Hs.237868 interleukin 7 receptor SeqlDNo.C1288.C343
428486 AW583497 Hs.184604 pancreatic polypeptide SeqlD o.C1298.C344
457489 AI693815 Hs.127179 cryptic gene SeqlDNo.C1308.C345
432874 W94322 Hs.279651 melanoma inhibitory activity SeqlDNo.C131S.C346
445891 AW391342 Hs.199460 DPCR1 protein SeqlDNo.C1328.C347
445891 AW391342 Hs.199460 DPCR1 protein SeqlDNo.C1338.C348
404682 ortholog of mouse polydomain protein Se lD o.C1348.C349
429547 AW009166 Hs.99376 FGENESH predicted novel secreted protein SeqlDNo.C1358.C350
404287 FGENESH predicted novel CUB-domain conta SeqlDNo.C1368.C351
404287 FGENESH predicted novel CUB-domain conta SeqlDNo.C1378.C352
404287 FGENESH predicted novel CUB-domain conta SeqlDNo.C1388.C353
418318 U47732 Hs.84072 transmembrane 4 superfamily member 3 Se lDNo.C139S.C354
444754 T83911 Hs.11881 transmembrane 4 superfamily member 4 SeqlDNo.C1408.C355
432596 AJ224741 Hs.278461 matrilin 3 Seq ID No. C141 & C356
444006 BE395085 Hs.334762 type I transmembrane protein Fn14 SeqlDNo.C1428.C357
428505 AL035461 Hs.2281 chromogranin B (secretogranin 1) Seq ID No. C1438. C358
448844 AI581519 Hs.177164 FGENESH predicted novel cell surface pr SeqlDNo.C1448.C359
448844 AI581519 Hs.177164 FGENESH predicted novel cell surfxe pr Seq ID No. C1458. C360
428392 H10233 Hs.2265 sxretory granule, neuroendocrine protei SeqlDNo.C1468.C361
448030 N30714 Hs.325960 membrane-spanning 4-domains, subfamily A SeqlDNo.C1478.C362
422109 S73265 Hs.1473 gastrin-releasing peptide Seq ID No. C148 & C363
449048 Z45051 Hs.22920 similar to S68401 (cattle) glucose indue Se lDNo.C1498.C364
417931 W95642 Hs.82961 trefoil fxtor 3 (intestinal) SeqlDNo.C1508.C365
419216 AU076718 Hs.164021 small inducible cytokine εubfamily B (Cy Seq ID No. C151 & C366
426227 U67058 Hs.154299 Human proteinase xtivated rxeptor-2 mR SeqlDNo.C'1528.C367
413554 AA319146 Hs.75426 s∞retogranin II (chromogranin C) Seq ID No. C1538. C368
445417 AK001058 Hs.12680 a disintegrin-like and metalloprotease w SeqlDNo. C1548, C369
426322 J05068 Hs.2012 transcobalamin I (vitamin B12 binding pr SeqlDNo.C1558.C370 413719 BE439580 Hs 75498 small inducible cytokine subfamily A (Cy Seq ID No C156 & C371
431462 AW583672 Hs 256311 granin like neuroend∞ππe peptide precu SeqlDNo C1578.C372
416498 U33632 Hs 79351 potassium channel subfamily K member 1 SeqlD o C1588.C373
413095 AA494359 Hs 30715 potassium voltage-gated channel Iskrel SeqlDNo C1598.C374
426125 X87241 Hs 166994 FAT tumor suppressor (Drosophila) homolo SeqlDNo C1608.C375
436729 BE621807 Hs 351316 transmembrane 4 superfamily member 1 Seq ID No C161 & C376
437145 AF007216 Hs 5462 solute earner family 4 sodium bicarbon SeqlDNo C1628.C377
451820 AW058357 Hs 199248 ESTs Se lDNo C163&C378
427557 NM 002659 Hs 179657 plasminogen xtivator, urokmase rxepto Se lDNo C1648.C379
408308 AL033377 Hs 44197 hypothetical protein DKFZp564D0462 SeqlDNo C1658.C380
421340 F07783 Hs 1369 decay xceleratmg factor for complement SeqlDNo C1668.C381
428187 AI687303 Hs 285529 G protein-coupled rxeptor 49 SeqlD o C1678.C382
428187 AI687303 Hs 285529 G protein-coupled rxeptor 49 SeqlD o C168S.C383
422278 AF072873 Hs 114218 fπzzled (Drosophila) homolog 6 SeqlDNo C169&C384
446619 AU076643 Hs313 sxreted phosphoprotein 1 (osteopontin SeqlDNo C1708.C385
419452 U33635 Hs 90572 PTK7 protein tyrosine kmase 7 Seq ID No C171 & C386
428242 H55709 Hs 2250 leukemia inhibitory factor (cholinergic Seq ID No C172 & C387
439659 AW970780 Hs 59483 leucine-nch repeat-containing G protein Seq ID No C173 & C388
411825 AK000334 Hs 352415 solute earner family 39 (zinc transport SeqlDNo C174S.C389
412314 AA825247 Hs 356084 G protein-coupled receptor 27 (GPR27) (S SeqlDNo C175&C390
429150 AF120103 Hs 197366 smoothened (Drosophila) homolog SeqlDNo C1768.C391
419073 AW372170 Hs 183918 transmembrane rxeptor Unc5H2 mRNA SeqlDNo C1778.C392
411828 AW161449 Hs 72290 wingless type MMTV integration site fami SeqlDNo C1788.C393
419508 AW997938 Hs 90786 ATP-bindmg cassette, sub-family C (CFTR SeqlDNo C1798.C394
421779 AI879159 Hs 108219 wingless-type MMTV integration site fami SeqlDNo C1808.C395
439668 AI091277 Hs 302634 frizzled (Drosophila) homolog 8 SeqlDNo C1818.C396
433336 AF017986 Hs 31386 sxreted fnzzled-related protein 2 (str SeqlDNo C182&C397
436972 AA284679 Hs 25640 claudin 3 SeqlDNo C1838.C398
410268 AA316181 Hs 61635 six transmembrane epithelial antigen of SeqlDNo C1848.C399
416370 N90470 Hs 203697 CD38 antigen (p45) SeqlDNo C1858.C400
437052 AA861697 Hs 120591 ESTs SeqlD o C1868.C401
421481 AW391972 Hs 104696 KIAA1324 protein SeqlD o C1878.C402
444151 AW972917 Hs 128749 alpha-methylxyl CoA rxemase SeqlDNo C188S.C403
426174 AA547959 Hs 115838 Homo sapiens similar to Echmoidin (LOC1 Seq ID No C189 & C404
410037 AB020725 Hs 58009 KIAA0918 protein Se lDNo C190S.C405
425071 NM.013989 Hs 154424 deiodmase, lodothyronme, type II SeqlDNo C191&C406
421829 AB018330 Hs 108708 calciumcalmodulin-dependent protein km SeqlDNo C1928.C407
418576 AW968159 Hs 302740 Epithelial calcium channel 2, CaT-like A SeqlD o C1938.C408
419693 AA133749 Hs 301350 FXYD domain-containing ion transport reg SeqlD o C1948.C409
419693 AA133749 Hs 301350 FXYD domain-containing ion transport reg SeqlDNo C1958.C410
448988 Y09763 Hs 22785 gamma-amiπobutyπc xid (GABA) A rxepto Se lDNo C196&C411
448988 Y09763 Hs 22785 gamma-aminobutyπc xid (GABA) A rxepto SeqlDNo C197S.C412
448988 Y09763 Hs 22785 gamma-amiπobutyπc xid (GABA) A rxepto SeqlDNo C198&C413
448988 Y09763 Hs 22785 gamma-aminobutyπc xid (GABA) A rxepto SeqlDNo C1998.C414
430144 AI732722 Hs 98927 ERGL protein, ERGIC-53-lιke protein Seq ID No C2008, C415
408833 AW612232 Hs 254835 ESTs Seq ID No C201 & C416
452017 AF109302 Hs 27495 prostate cancer assxiated protein 7 SeqlDNo C2028.C417
415992 C05837 Hs 145807 hypothetical protein FL 13593 Seq ID No C203 & C418
415992 C05837 Hs 145807 hypothetical protein FU 13593 SeqlDNo C2048.C419
443991 NM 002250 Hs 10082 potassium intermediatesmall conductance Se lDNo C205&C420
425976 C75094 Hs 334514 NG22 protein SeqlDNo C2068.C421
432800 BE391046 Hs 278962 AIM-1 protein SeqlD o C207S.C422
452955 AW390282 Hs 31130 transmembrane 7 superfamily member 2 Seq ID No C208 & C423
424339 BE257148 Hs 145416 endoglycan SeqlDNo C209S.C424
425263 NM 001197 Hs 155419 BCL2 interxting killer (apoptosis indue SeqlDNo C2108.C425
421537 BE383488 Hs 105547 neural proliferation, differentiation an SeqlDNo C2118.C426
434293 NM 004445 Hs 3796 EphB6 SeqlD o C2128.C427
427715 BE245274 Hs 180428 KIAA1181 protein Seq ID No C213 & C428
413049 NM 002151 Hs823 hepsin (transmembrane protease, seπne 1 SeqlDNo C214S.C429
414555 N98569 Hs 76422 phospholipase A2, group IIA (platelets, SeqlDNo C2158.C430
422424 AI186431 Hs 296638 prostate differentiation fxtor SeqlDNo C216&C431
432378 AI493046 Hs 146133 ESTs SeqlDNo C4328.C433
409041 AB033025 Hs 50081 Hypothetical protein XP.051860 (KIAA119 SeqlDNo C4348.C435
TABLE 79B
Pkey Unique Eos probeset identifier number
CAT number Gene cluster number Accession Genbank xcesεion numbers
Pkey CAT Number Accession
414991 1785136.1 D78831 C17898D78863
TABLE 79C
Pkey Unique number corresponding to an Eos probeset
Ref Sequence source The 7 digit numbers in this column are Genbank Identifier (Gl) numbers "Dunham I et al " refers to the publication entitled "The DNA sequence of human chromosome 22" Dunhaml etal, Nature (1999) 402489495 Strand Indicates DNA strand from which exons were predicted
NLposition Indicates nucleotide positions of predicted exons
Pkey Ref Strand NLposition 404682 9797231 Minus 40977-41150
404287 2326514 Plus 53134-53281
404287 2326514 Plus 53134-53281
404287 2326514 Plus 53134-53281
Table 80:
Seq ID NO: Cl DNA Sequence Nucleic Acid Accession #: NM_005814 Coding sequence: 345..1304
1 11 21 31 41 51
I I I I I I
CTACCCCTTT GTGAGCAGTC TAGGACTTTG TACACCTGTT AAGTAGGGAG AAGGCAGGGG 60 AGGTGGCTGG TTTAAGGGGA ACTTGAGGGA AGTAGGGAAG ACTCCTCTTG GβACCTTTGG 120
AGTAGGTGAC ACATGAGCCC AGCCCCAGCT CACCTGCCAA TCCAGCTGAG GAGCTCACCT 180
GCCAATCCAβ CTGAGGCTGG GCAGAGCTGG GTGAGAAGAG GβAAAATTGC AGGGACCTCC 240
AGTTGGGCCA GGCCAGAAGC TGCTGTAGCT TTAACCAGAC AGCTCAGACC TGTCTGGAGG 300
CTGCCAGTGA CAGGTTAGGT TTAGGGCAGA GAAGAAGCAA GACCATGGTG GGGAAβATGT 360
GGCCTGTGTT GTGGACACTC TGTGCAGTCA GGGTGACCGT CGATGCCATC TCTGTβGAAA 420
CTCCGCAGGA CGTTCTTCGG βCTTCGCAGG GAAAGAGTGT CACCCTGCCC TGCACCTACC 480
ACACTTCCAC CTCCAGTCGA GAβGGACTTA TTCAATGGGA TAAGCTCCTC CTCACTCATA 540
CGGAAAGGGT GGTCATCTGG CCGTTTTCAA ACAAAAACTA CATCCATGGT GAGCTTTATA 600
AβAATCGCGT CAGCATATCC AACAATGCTG AGCAGTCCGA TGCCTCCATC ACCATTGATC 660
AGCTGACCAT GCCTGACAAC GGCACCTACG AGTGTTCTGT CTCGCTGATG TCAGACCTGG 720
AGβGCAACAC CAAβTCACGT GTCCGCCTβT TGGTCCTCGT GCCACCCTCC AAACCACAAT 780
GCGGCATCGA GGGAGAGACC ATAATTGGGA ACAACATCCA GCTGACCTGC CAATCAAAGβ 840
AGGGCTCACC AACCCCTCAG TACAGCTGGA AGAGGTACAA CATCCTGAAT CAGGAGCAGC 900
CCCTGGCCCA GCCAGCCTCA GGTCAGCCTG TCTCCCTGAA GAATATCTCC ACAGACACAT 960
CGβGTTACTA CATCTGTACC TCCAGCAATG AGGAGGGGAC GCAGTTCTGC AAGATCACGG 1020
TGβCCCTCAG ATCTCCCTCC ATGAACGTGG CCCTGTATGT GGGCATCGCG GTGGGCGTGG 1080
TTGCAGCCCT CATTATCATT GGCATCATCA TCTACTGCTG CTGCTGCCGA βGGAAGGACβ 1140
ACAACACTGA AGACAAGGAG GATGCAAGGC CGAACCGGGA AGCCTATGAG 6A6CCACCAG 1200
AGCAGCTAAG AGAACTTTCC AGAGAGAGGG AGGAGGAGGA TGACTACAGG CAAGAAGAGC 1260
AGAGGAGCAC TGGGCGTGAA TCCCCGGACC ACCTCGACCA GTGACAGGCC AGCAGCAGAG 1320
GβCGGCGGAβ GAAGGGTTAG GGGTTCATTC TCCCGCTTCC TGβCCTCCCT TCTCCTTTCT 1380
AAGCCCTGTT CTCCTGTCCC TCCATCCCAG ACATTGATGG GGACATTTCT TCCCCAGTGT 1440
CAGCTGTGGG GAACATGGCT GGCCTGGTAA GGGGGTCCCT GTGCTGATCC TGCTGACCTC 1500
ACTβTCCTGT GAAGTAACCC CTCCTGGCTG TGACACCTGG TGCGGGCCTG GCCCTCACTC 1560
AAGACCAGGC TGCAβCCTCC ACTTCCCTCβ TAβTTGGCAG GAGCTCCTGG AAGCACAGCβ 1620
CTGAGCATGG GGCGCTCCCA CTCAGAACTC TCCAGGGAGG CGATGCCAGC CTTGGGGGGT 1680
GGGGGCTGTC CTGCTCACCT GTβTGCCCAG CACCTGGAGG GGCACCAGGT GGAβGGTTTG 1740
CACTCCACAC ATCTTTCTTG AATGAATβAA AGAATAAGTG AGTATGCTTG GβCCCTGCAT 1800
TGGCCTGGCC TCCAGCTCCC ACTCCCTTTC CAACCTCACT TCCCGTAGCT GCCAGTATGT 1860
TCCAAACCCT CCTGGGAAGG CCACCTCCCA CTCCTGCTGC ACAGGCCCTG GGGAGCTTTT 1920
GCCCACACAC TTTCCATCTC TGCCTGTCAA TATCGTACCT GTCCCTCCAG βCCCATCTCA 1980
AATCACAAGG ATTTCTCTAA CCCTATCCTA ATTGTCCACA TACGTGGAAA CAATCCTGTT 2040
ACTCTGTCCC ACGTCCAATC ATGGGCCACA AGGCACAGTC TTCTGAGCGA GTGCTCTCAC 2100
TGTATTAGAG CGCCAGCTCC TTGGGGCAGG GCCTGGGCCT CATGGCTTTT GCTTTCCCTG 2160
AAGCCCTAGT ACCTGGCGCC CATCCTAGTG GGCACTTAAG CTTAATTGGG GAAACTGCTT 2220
TGATTGGTTG TGCCTTCCCT TCTCTGGTCT CCTTGAGATG ATCGTAGACA CAGGGATGAT 2280
TCCCACCCAA ACCCACGTAT TCATTCAGTG AGTTAAACAC GAATTGATTT AAAGTGAACA 2340
CACACAAGGG AGCTTGCTTG CAβATGGTCT GAGTTCTTGT GTCCTGGTAA TTCCTCTCCA 2400
GGCCAGAATA ATTGGCATGT CTCCTCAACC CACATGGGGT TCCTGGTTGT TCCTGCATCC 2460
CGATACCTCA GCCCTGGCCC TGCCCAGCCC ATTTGGGCTC TGGTTTTCTG GTGGGGCTGT 2520
CCTGCTGCCC TCCCACAGCC TCCTTCTGTT TGTCGAGCAT TTCTTCTACT CTTGAGAGCT 2580
CAGGCAGCGT TAGGGCTGCT TAGGTCTCAT GGACCAGTGβ CTGGTCTCAC CCAACTGCAG 2640
TTTACTATTG CTATCTTTTC TGGATGATCA GAAAAATAAT TCCATAAATC TATTGTCTAC 2700
TTGCGATTTT TTAAAAAATβ TATATTTTTA TATATATTGT TAAATCCTTT GCTTCATTCC 2760
AAATGCTTTC AGTAATAATA AAATTGTGGG TGG 2793
Seq ID NO: C2 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 1..3150
1 11 21 31 41 51
I I I I I I
ATGGGGAGCC GβACGCCAGA GTCCCCTCTC CACGCCGTGC AGCTGCGCTG GGGCCCCCGG 60
CGCCGACCCC CGCTSSTGCC GCTGCTGTTG CTGCTSSTGC CGCCGCCACC CAGGGTCGGG 120
GGCTTCAACT TAGACGCGGA GGCCCCAGCA GTACTCTCGG GGCCCCCGGG CTCCTTCTTC 180
GβATTCTCAG TGGAGTTTTA CCGGCCGGGA ACAGACGGGG TCAGTGTGCT GGTGGGAGCA 240
CCCAAGGCTA ATACCAGCCA GCCAGGAGTG CTGCAGGGTG GTGCTGTCTA CCTCTGTCCT 300
TGGGGTGCCA GCCCCACACA GTGCACCCCC ATTGAATTTG ACAGCAAAGG CTCTCGGCTC 360
CTGGAGTCCT CACTGTCCAG CTCAGAGGGA GAGGAGCCTG TGGAGTACAA GTCCTTGCAG 420
TGGTTCGGGG CAACAGTTCG AGCCCATGGC TCCTCCATCT TGGCATGCGC TCCACTGTAC 480
AGCTGGCβCA CA6AGAAGGA GCCACTGAGC GACCCCGTGG GCACCTGCTA CCTCTCCACA 540
GATAACTTCA CCCGAATTCT GGAGTATGCA CCCTGCCGCT CAGATTTCAG CTGGGCAGCA 600
GGACAGGGTT ACTGCCAAGG AGGCTTCAGT GCCGAGTTCA CCAAGACTGG CCGTGTGGTT 660
TTAGGTGGAC CAGGAAβCTA TTTCTGGCAA GGCCAGATCC TGTCTGCCAC TCAGGAGCAG 720
ATTGCAGAAT CTTATTACCC CGAGTACCTG ATCAACCTGG TTCAGGGGCA GCTGCAGACT 780
CGCCAGGCCA GTTCCATCTA TGATGACAGC TACCTAGGAT ACTCTGTGGC TGTTGGTGAA 840
TTCAGTGGTG ATGACACAGA AGACTTTGTT GCTGGTGTGC CCAAAGGGAA CCTCACTTAC 900
GGCTATGTCA CCATCCTTAA TGGCTCAGAC ATTCGATCCC TCTACAACTT CTCAGGGGAA 960
CAGATGGCCT CCTACTTTGG CTATGCAGTG GCCGCCACAG ACGTCAATGG GGACGGGCTG 1020
GATGACTTGC TGGTGGGGGC ACCCCTGCTC ATGGATCGβA CCCCTGACGG GCGGCCTCAβ 1080
GAGGTGGGCA GGGTCTACGT CTACCTGCAG CACCCAGCCG GCATAGAGCC CACGCCCACC 1140
CTTACCCTCA CTGGCCATGA TGAGTTTGGC CGATTTGGCA GCTCCTTGAC CCCCCTGGGG 1200
GACCTGGACC AGGATGGCTA CAATGATGTG GCCATCGGGG CTCCCTTTGG TGGGGAGACC 1260
CAGCAGGGAβ TAGTGTTTGT ATTTCCTGGG GGCCCAGGAG GGCTGGGCTC TAAGCCTTCC 1320 CAGGTTCTGC ACCCCCTGTG GGCAGCCAβC CACACCCCAG ACTTCTTTGG CTCTGCCCTT 1380
CGAGGAGGCC GAGACCTG6A TGGCAATGβA TATCCTGATC TGATTβTGGG GTCCTTTGGT 1440
GTGGACAAGβ CT6TGGTATA CAGGGGCCGC CCCATCGTGT CCGCTAGTGC CTCCCTCACC 1500
ATCTTCCCCG CCATGTTCAA CCCAGAGGAG CGGAGCTGCA GCTTAGAGGG GAACCCTGTG 1560
GCCTGCATCA ACCTTAGCTT CTGCCTCAAT GCTTCTGGAA AACACGTTGC TGACTCCATT 1620
GGTTTCACAG TGGAACTTCA GCTGGACTGG CAGAAGCAGA AGGGAGGGGT ACGGCGGGCA 1680
CTGTTCCTGG CCTCCAGGCA GGCAACCCTG ACCCAGACCC TGCTCATCCA GAATGGGGCT 1740
CGAGAGGATT GCAGAGAGAT GAAGATCTAC CTCAGGAACG AGTCAGAATT TCGAGACAAA 1800
CTCTCGCCGA TTCACATCGC TCTCAACTTC TCCTTGGACC CCCAAGCCCC AGTGGACAGC 1860
CACGGCCTCA GGCCACCCCT ACATTATCAG AGCAAGAGCC GGATAGAGGA CAAGGCTCAG 1920
ATCTTβCTGG ACTGTGGAGA AGACAACATC TGTGTGCCTG ACCTGCAGCT GGAAGT6TTT 1980
GGGGAGCAGA ACCATGTGTA CCTGGGTGAC AAGAATGCCC TGAACCTCAC TTTCCATGCC 2040
CAGAATGTGG GTGAGGGTGG CGCCTATGAG GCTGAGCTTC GGGTCACCGC CCCTCCAGAG 2100
GCTGAGTACT CAGGACTCGT CAGACACCCA GGGAACTTCT CCAGCCTGAG CTGTGACTAC 2160
TTTGCCGTGA ACCAGAGCCG CCTGCTGGTG TGTGACCTGβ GCAACCCCAT GAAGGCAGGA 2220
GCCAGTCTGT GβGGTββCCT TCGGTTTACA GTCCCTCATC TCCGGGACAC TAAGAAAACC 2280
ATCCAGTTTG ACTTCCAGAT CCTCAGCAAG AATCTCAACA ACTCGCAAAG CGACGTGGTT 2340
TCCTTTCGGC TCTCCGTGGA GGCTCAGGCC CAGGTCACCC TGAACGGTGT CTCCAAGCCT 2400
GAGGCAGTGC TATTCCCAGT AAC∞ACTGG CATCCCCGAβ ACCAGCCTCA GAAGGAGGAG 2460
GACCTGGGAC CTGCTGTCCA CCATGTCTAT GAGCTCATCA ACCAAGGCCC CAGCTCCATT 2520
AGCCAGGGTG TGCTGGAACT CAGCTGTCCC CAGGCTCTGG AAGGTCACCA GCTCCTATAT 2580
GTGACCAGAG TTACGGGACT CAACTGCACC ACCAATCACC CCATTAACCC AAAGGGCCTG 2640
GAGTTGGATC CCGAGGGTTC CCTGCACCAC CAGCAAAAAC GGGAAβCTCC AAGCCGCAGC 2700
TCTGCTTCCT CGββACCTCA βATCCTGAAA TGCCCGGAGG CTGAGTGTTT CAGGCTGCGC 2760
TGTGAβCTCG GGCCCCTGCA CCAACAAGAG AGCCAAAGTC TGCAGTTGCA TTTCCGAGTC 2820
TGGβCCAAGA CTTTCTTGCA GCGGGAGCAC CAGCCATTTA GCCTGCAGTG TGAββCTGTG 2880
TACAAAGCCC TGAAGATGCC CTACCβAATC CTβCCTCGGC AGCTGCCCCA AAAAβAβCGT 2940
CAGGTGGCCA CAGCTGTGCA ATGGACCAAG GCAGAAGβCA GCTATGGCGT CCCACTGTGG 3000
ATCATCATCC TAGCCATCCT GTTTGGCCTC CTGCTCCTAG GTCTACTCAT CTACATCCTC 3060
TACAAGCTTG βATTCTTCAA ACGCTCCCTC CCATATGGCA CCGCCATGGA AAAAGCTCAG 3120
CTCAAGCCTC CAGCCACCTC TβATGCCTGA 3150
Seq ID NO: C3 DNA Sequence Nucleic Acid Accession ff: NM_002421.2 Coding sequence: 1..1410
1 11 21 31 41 51
I I I I I I
ATGCACAGCT TTCCTCCACT GCTCCTGCTG CTGTTCTGGβ GTGTGβTGTC ACACAGCTTC 60
CCAβCGACTC TAGAAACACA AGAGCAAGAT GTGGACTTAβ TCCAGAAATA CCTGGAAAAA 120
TACTACAACC TGAAGAATGA TGGGAGGCAA GTTGAAAAGC GGAGAAATAG TGGCCCAGTG 180
GTTGAAAAAT TβAAGCAAAT GCAGGAATTC TTTGβGCTGA AAGTGACTGG GAAACCAGAT 240
GCTGAAACCC TGAAGGTGAT GAAGCAGCCC AGATβTGGAG TGCCTGATGT GGCTCAGTTT 300
GTCCTCACTG AGGGGAACCC TCGCTGGGAG CAAACACATC TGACCTACAG GATTGAAAAT 360
TACACGCCAG ATTTGCCAAG AGCAGATGTG GACCATGCCA TTGAGAAAGC CTTCCAACTC 420
TGGAGTAATG TCACACCTCT GACATTCACC AAGGTCTCTG AGβGTCAAGC AGACATCATG 480
ATATCTTTTG TCAGGGGAGA TCATCGGGAC AACTCTCCTT TTGATGGACC TGGAGGAAAT 540
CTTGCTCATG CTTTTCAACC AGGCCCAGβT ATTGGAGGGG ATGCTCATTT TGATGAAGAT 600
GAAAGGTGGA CCAACAATTT CAGAGAGTAC AACTTACATC GTGTTβCGGC TCATGAACTC 660
GβCCATTCTC TTGGACTCTC CCATTCTACT GATATCGGGG CTTTGATGTA CCCTAGCTAC 720
ACCTTCAGTG GTGATGTTCA GCTAGCTCAG GATGACATTG ATGGCATCCA AGCCATATAT 780
GGACCTTCCC AAAATCCTGT CCAGCCCATC GGCCCACAAA CCCCAAAAGC ATGTGACAGT 840
AAGCTAACCT TTGATGCTAT AACTACGATT CGGGGAGAAG TGATGTTCTT TAAAGACAGA 900
TTCTACATGC GCACAAATCC CTTCTACCCG GAAGTTGAGC TCAATTTCAT TTCTGTTTTC 960
TGGCCACAAC TGCCAAATGG GCTTGAAβCT βCTTACGAAT TTGCCGACAG AGATGAAGTC 1020
CGGTTTTTCA AAGGGAATAA GTACTGGGCT GTTCAGGGAC AGAATGTGCT ACACGGATAC 1080
CCCAAG6ACA TCTACAGCTC CTTTββCTTC CCTAGAACTG TGAAGCATAT CGATGCTGCT 1140
CTTTCTGAGG AAAACACTGG AAAAACCTAC TTCTTTGTTG CTAACAAATA CTGGAGGTAT 1200
GATGAATATA AACGATCTAT GGATCCAGβT TATCCCAAAA TGATAGCACA TGACTTTCCT 1260
GGAATTGGCC ACAAAGTTGA TGCAGTTTTC ATGAAAGATG GATTTTTCTA TTTCTTTCAT 1320
GGAACAAGAC AATACAAATT TGATCCTAAA ACGAAGAGAA TTTTGACTCT CCAGAAAGCT 1380
AATAGCTGGT TCAACTGCAG GAAAAATTAG 1410
Seq ID NO: C4 DNA Sequence Nucleic Acid Accession ff : Eos sequence
Coding sequence: 1. .1410
1 11 21 31 41 51
I I I I I I
ATGCACAβCT TTCCTCCACT GCTGCTGCTG CTGTTCTGGG GTGTGGTGTC ACACAGCTTC 60
CCAGCGACTC TAGAAACACA AGAGCAAGAT GTGGACTTAG TCCAGAAATA CCTGGAAAAA 120
TACTACAACC TGAAGAATGA TGGGAGGCAA GTTGAAAAGC GGAGAAATAG TGGCCCAGTG 180
GTTGAAAAAT TGAAGCAAAT GCAGGAATTC TTTGGGCTβA AAGTGACTGG GAAACCAGAT 240
GCTGAAACCC TGAAGGTGAT GAAGCAGCCC AGATGTGGAG TGCCTGATGT GGCTCAGTTT 300
GTCCTCACTG AGGGGAACCC TCGCTGGGAG CAAACACATC TGACCTACAG GATTGAAAAT 360
TACACGCCAβ ATTTGCCAAG AGCAGATGTG GACCATβCCA TTGAGAAAGC CTTCCAACTC 420
TGGAGTAATG TCACACCTCT GACATTCACC AAGGTCTCTG AGGGTCAACC AGACATCATG 480
ATATCTTTTG TCAGGGGAGA TCATCGGGAC AACTCTCCTT TTGATGGACC TGGAGGAAAT 540
CTTGCTCATG CTTTTCAACC AGGCCCAGGT ATTGGAGGGG ATGCTCATTT TGATGAAGAT 600
GAAAGGTGGA CCAACAATTT CAGAGAGTAC AACTTACATC GTGTTGCGGC TCATGCCCTC 660
GGCCATTCTC TTGGACTCTC CCATTCTACT GATATCGGGG CTTTGATGTA CCCTAGCTAC 720
ACCTTCAGTG GTGATGTTCA GCTAGCTCAG GATGACATTG ATGGCATCCA AGCCATATAT 780
GGACCTTCCC AAAATCCTGT CCAGCCCATC GGCCCACAAA CCCCAAAAGC ATGTGACAGT 840
AAGCTAACCT TTGATGCTAT AACTACGATT CGGGGAGAAG TGATGTTCTT TAAAGACAGA 900 TTCTACATGC GCACAAATCC CTTCTACCCG GAAGTTGAGC TCAATTTCAT TTCTGTTTTC 960 TGGCCACAAC TGCCAAATGG GCTTGAAGCT GCTTACGAAT TTGCCGACAG AGATGAAGTC 1020 CGGTTTTTCA AAGGGAATAA GTACTGGGCT GTTCAGGGAC AGAATβTGCT ACACGGATAC 1080 CCCAAGGACA TCTACAGCTC CTTTGGCTTC CCTAGAACTG TGAAGCATAT CGATGCTGCT 1140 CTTTCTGAGG AAAACACTGG AAAAACCTAC TTCTTTGTTG CTAACAAATA CTGGAGGTAT 1200 GATGAATATA AACβATCTAT GGATCCAGGT TATCCCAAAA TGATAGCACA TGACTTTCCT 1260 GGAATTββCC ACAAAGTTGA TGCAGTTTTC ATGAAAGATG GATTTTTCTA TTTCTTTCAT 1320 GGAACAAGAC AATACAAATT TGATCCTAAA ACGAAGAGAA TTTTGACTCT CCAGAAAGCT 1380 AATAGCTGGT TCAACTGCAG GAAAAATTAG 1410
Seq ID NO: C5 DNA Sequence
Nucleic Acid Accession #: NM_014331.2
Coding sequence: 1..1506
1 11 21 31 41 51
I I J 1 I 1 | 1 1
ATGGTCAβAA AGCCTGTTGT GTCCACCATC TCCAAAGGAG GTTACCTGCA GβGAAATGTT 60 AACGGGAGGC TGCCTTCCCT GGGCAACAAG GAGCCACCTG GβCAGGAGAA AGTGCAGCTG 120 AAGAGβAAAβ TCACTTTACT GAGGGGAGTC TCCATTATCA TTGGCACCAT CATTGGAGCA 180 GGAATCTTCA TCTCTCCTAA GGGCGTGCTC CAGAACACCG GCAGCGTGGG CATGTCTCTG 240 ACCATCTGGA CGGTGTGTGG GGTCCT6TCA CTATTTββAβ CTTTGTCTTA TGCTGAATTG 300 GβAACAACTA TAAAβAAATC TβGAGGTCAT TACACATATA TTTTGβAAGT CTTTGGTCCA 360 TTACCAGCTT TTGTACGAGT CTGGGTGGAA CTCCTCATAA TACGCCCTGC AGCTACTGCT 420 GTGATATCCC TGGCATTTGG ACGCTACATT CTGGAACCAT TTTTTATTCA ATGT6AAATC 480 CCTGAACTTG CGATCAAGCT CATTACAGCT GTGGGCATAA CTGTAGTGAT GGTCCTAAAT 540 AGCATGAGTG TCAGCTGGAG CGCCCGGATC CAGATTTTCT TAACCTTTTG CAAGCTCACA 600 GCAATTCTGA TAATTATAGT CCCTGGAGTT ATCCACCTAA TTAAAGGTCA AACGCAGAAC 660 TTTAAAGACG CGTTTTCAGG AAGAGATTCA AβTATTACβC GGTTGCCACT GGCTTTTTAT 720 TATGGAATGT ATGCATATGC TGGCTGGTTT TACCTCAACT TTGTTACTβA AGAAGTAGAA 780 AACCCTGAAA AAACCATTCC CCTTGCAATA TGTATATCCA TGGCCATTGT CACCATTGGC 840 TATGTGCTGA CAAATGTGGC CTACTTTACG ACCATTAATG CTGAGβAGCT GCT6CTTTCA 900 AATGCAβTGG CAGTGACCTT TTCTGAGCGG CTACTGGGAA ATTTCTCATT AGCAGTTCCβ 960 ATCTTTGTTG CCCTCTCCTG CTTTGGCTCC ATGAACGβTβ βTβTGTTTβC TGTCTCCAGG 1020 TTATTCTATG TTGCGTCTCG AGAGGGTCAC CTTCCAGAAA TCCTCTCCAT GATTCATGTC 1080 CGCAAGCACA CTCCTCTACC AGCTGTTATT GTTTTGCACC CTTTGACAAT GATAATGCTC 1140 TTCTCTGGAG ACCTCGACAG TCTTTTGAAT TTCCTCAGTT TTGCCAGGTG GCTTTTTATT 1200 GGGCTGGCAG TTGCTGGGCT GATTTATCTT CGATACAAAT GCCCAGATAT GCATCGTCCT 1260 TTCAAGGTGC CACTGTTCAT CCCAGCTTTG TTTTGCTTCA CATGCCTCTT CATGGTTGCC 1320 CTTTCCCTCT ATTCGGACCC ATTTAGTACA GGGATTGGCT TCβTCATCAC TCTGACTGGA 1380 GTCCCTGCGT ATTATCTCTT TATTATATGG GACAAGAAAC CCAGβTGGTT TAGAATAATG 1440 TCAGAGAAAA TAACCAGAAC ATTACAAATA ATACTGβAAG TTGTACCAGA AGAAGATAAG 1500 TTATGAACTA ATGGACTTGA GATCTTGGCA ATCTGCCCAA GGG6AGACAC AAAATAGGGA 1560 TTTTTACTTC ATTTTCTGAA AGTCTAGAGA ATTACAACTT TGGTβATAAA CAAAAGGAGT 1620 CAGTTATTTT TATTCATATA TTTTAβCATA TTCGAACTAA TTTCTAAGAA ATTTAGTTAT 1680 AACTCTATβT AGTTATAGAA AGTGAATATG CAGTTATTCT ATGAGTCGCA CAATTCTTGA 1740 GTCTCTGATA CCTACCTATT GGGGTTAGGA GAAAAGACTA GACAATTACT ATGTβGTCAT 1800 TCTCTACAAC ATATGTTAGC ACGGCAAAGA ACCTTCAAAT TGAAGACTGA GATTTTTCTG 1860 TATATATGGG TTTTGTAAAβ ATGGTTTTAC ACACTACAGA TGTCTATACT GTGAAAAGTG 1920 TTTTCAATTC TGAAAAAAAG CATACATCAT GATTATββCA AAGAGGAGAG AAAGAAATTT 1980 ATTTTACATT GACATTGCAT TGCTTCCCCT TAGATACCAA TTTAGATAAC AAACACTCAT 2040 GCTTTAATGG ATTATACCCA GAGCACTTTG AACAAAGGTC AGTGGGGATT GTTGAATACA 2100 TTAAAGAAGA 6TTTCTAGGG GCTACTGTTT ATGAGACACA TCCAGβAβTT ATGTTTAAGT 2160 AAAAATCCTT GAGAATTTAT TATGTCAGAT GTTTTTTCAT TCATTATCAG GAAGTTTTAG 2220 TTATCTGTCA T TTTTTTTT TCACATCAGT TTGATCAGGA AAGTGTATAA CACATCTTAβ 2280 AGCAAGAGTT AGTTTGGTAT TAAATCCTCA TTAGAACAAC CACCTGTTTC ACTAATAACT 2340 TACCCCTGAT GAGTCTATCT AAACATATGC ATTTTAAGCC TTCAAATTAC ATTATCAACA 2400 TGAGAGAAAT AACCAACAAA GAAGATGTTC AAAATAATAG TCCCATATCT GTAATCATAT 2460 CTACATGCAA TGTTAGTAAT TCTGAAGTTT TTTAAATTTA TGGCTATTTT TACA∞ATβA 2520 TGAATTTTGA CAGTTTGTGC ATTTTCTTTA TACATTTTAT ATTCTTCTGT TAAAATATCT 2580 CTTCAGATGA AACTGTCCAG ATTAATTAGG AAAAGGCATA TATTAACATA AAAATTGCAA 2640 AAGAAATGTC GCTGTAAATA AGATTTACAA CTGATGTTTC TAGAAAATTT CCACTTCTAT 2700 ATCTAGGCTT TβTCAGTAAT TTCCACACCT TAATTATCAT TCAACTTGCA AAAGAβACAA 2760 CTGATAAGAA GAAAATTGAA ATGAGAATCT GTGGATAAGT GTTTGTGTTC AGAAGATGTT 2820 GTTTTGCCAG TATTAGAAAA . TACTGTβAβC CGGGCATGGT GGCTTACATC TGTAATCCCA 2880 GCACTTTGGG AGGCTGAGββ GGTGGATCAC CTGAGGTCGG GAGTTCTAGA CCAGCCTGAC 2940 CAACATGGAG AAACCCCATC 1 TCTACTAAAA ATACAAAATT AGCTGGGCAT GGTGGCACAT 3000 GCTGGTAATC TCAGCTATTG 1 AGGAGGCTGA GGCAGGAGAA TTGCTTGAAC CCGGGAGGCβ 3060 GAGGTTGCAG TGAGCCAAGA . TTGCACCACT GTACTCCAGC CTGGGTGACA AAGTCAGACT 3120 CCATCTCCAA AAAAAAAAAA . AAAA 3144
Seq ID NO: C6 DNA Sequence
Nucleic Acid Accession #: NM_003246.1
Coding sequence: 112..3624
11 21 31 41 51
I I I I I
GGACGCACAG GCATTCCCCG CGCCCCTCCA GCCCTCGCCG CCCTCGCCAC CGCTCCCGGC 60 CGCCGCGCTC CGGTACACAC AGGATCCCTG CTGGGCACCA ACAGCTCCAC CATGGGGCTG 120 GCCTGGGGAC TAGGCβTCCT GTTCCTGATG CATGTGTGTG GCACCAACCG CATTCCAGAG 180 TCTGGCGβAG ACAACAGCGT GTTTGACATC TTTGAACTCA CCGGββCCCC CCGCAAGGGG 240 TCTGGGCGCC GACTGGTGAA GGGCCCCGAC CCTTCCAGCC CAGCTTTCCG CATCGAGGAT 300 GCCAACCTGA TCCCCCCTGT GCCTβATβAC AAGTTCCAAG ACCTGGTGGA TGCTGTGCGG 360 βCAGAAAAGG GTTTCCTCCT TCTGGCATCC CTGAGGCAGA TGAAGAAGAC CCGGGGCACG 420 CTGCTGGCCC TGGAGCGGAA AGACCACTCT GβCCAGGTCT TCAGCGTGGT GTCCAATGGC 480
AAGGCGGGCA CCCTGGACCT CAGCCTGACC GTCCAAGGAA AGCAGCACGT GGTGTCTGTG 540
GAAGAAGCTC TCCTGGCAAC CGβCCAGTGG AAGAGCATCA CCCTGTTTCT GCAGGAAGAC 600
AGGGCCCAGC TGTACATCGA CTGTGAAAAG ATGβAGAATG CTGAGTTGGA CGTCCCCATC 660
CAAAGCGTCT TCACCAGAGA CCTGGCCAGC ATCGCCAGAC TCCGCATCGC AAAGGGGGGC 720
GTCAATGACA ATTTCCAGGG GGTGCTGCAG AATGTGAGGT TTGTCTTTGG AACCACACCA 780
GAAGACATCC TCACGAACAA AGGCTGCTCC AGCTCTACCA GTGTCCTCCT CACCCTTGAC 840
AACAACGTGG TGAATGGTTC CAGCCCTβCC ATCCGCACTA ACTACATTβG CCACAAGACA 900
AAGGACTTGC AAGCCATCTG CGGCATCTCC TGTGATGAGC TGTCCAGCAT GGTCCTGGAA 960
CTCAGGGGCC TGCGCACCAT TGTGACCACG CTβCAGGACA GCATCCGCAA AGTGACTGAA 1020
GAGAACAAAβ AGTTGGCCAA TGAGCTGAGG CGGCCTCCCC TATGCTATCA CAACGGAGTT 1080
CAGTACAGAA ATAACGAGGA ATGGACTGTT βATAGCTGCA CTGAGTGTCA CTGTCAGAAC 1140
TCAGTTACCA TCTGCAAAAA GGTGTCCTGC CCCATCATGC CCTGCTCCAA TGCCACAGTT 1200
CCTGATGGAβ AATGCTGTCC TCGCTGTTGG CCCAGCGACT CTGCGGACGA TGGCTGGTCT 1260
CCATGGTCCG AGTGGACCTC CTGTTCTACG AGCTGTGGCA ATGGAATTCA GCAβCGCGGC 1320
CGCTCCTβCβ ATAGCCTCAA CAACCGATGT GAβGGCTCCT CGβTCCAGAC ACGGACCTGC 1380
CACATTCAGβ AGTGTGACAA AAGATTTAAA CAGGATGGTG GCTGGAGCCA CTGGTCCCCG 1440
TGGTCATCTT βTTCTGTGAC ATGTGGTGAT GβTGTGATCA CAAGGATCCG GCTCTGCAAC 1500
TCTCCCAGCC CCCAGATGAA TGGGAAACCC TGTGAAGGCG AAGCGCGGGA GACCAAAGCC 1560
TGCAAGAAAG ACGCCTGCCC CATCAATGGA GGCTGGGGTC CTTGGTCACC ATGGGACATC 1620
TGTTCTGTCA CCTGTGGAGG AGGGGTACAG AAACGTAGTC CTCTCTGCAA CAACCCCGCA 1680
CCCCAGTTTG GAGGCAAGGA CTGCGTTGGT GATGTAACAG AAAACCAGAT CTGCAACAAG 1740
CAGGACTGTC CAATTGATGG ATGCCTGTCC AATCCCTGCT TTGCCGGCGT GAAGTGTACT 1800
AGCTACCCTG ATGGCAGCTG GAAATGTGGT GCTTGTCCCC CTGGTTACAG TGGAAATGGC 1860
ATCCAGTGCA CAGATGTTGA TGAGTGCAAA GAAGTGCCTG ATGCCTGCTT CAACCACAAT 1920
GGAβAβCACC GGT6TGAGAA CACGGACCCC GGCTACAACT GCCTGCCCTG CCCCCCACGC 1980
TTCACCGGCT CACAGCCCTT CGGCCAGβGT GTCGAACATG CCACGGCCAA CAAACAGGTG 2040
TGCAAGCCCC GTAACCCCTG CACGGATGGG ACCCACGACT GCAACAAGAA CGCCAAGTGC 2100
AACTACCTGG GCCACTATAG CGACCCCATG TACCGCTGCG AGTGCAAGCC TβGCTACGCT 2160
GβCAATGGCA TCATCTGCGG GβAGGACACA GACCTGGATG GCTGGCCCAA TGAGAACCTG 2220
GTGTGCGTGβ CCAATGCGAC TTACCACTGC AAAAAGGATA ATTGCCCCAA CCTTCCCAAC 2280
TCAGGGCAGβ AAβACTATGA CAAGGATGGA ATTGGTGATG CCTGTGATGA TGACGATGAC 2340
AATGATAAAA TTCCAGATGA CAGGGACAAC TGTCCATTCC ATTACAACCC AβCTCAGTAT 2400
GACTATGACA GAGATGATGT GGGAGACCGC TGTGACAACT GTCCCTACAA CCACAACCCA 2460 βATCAβGCAG ACACAGACAA CAATGGGGAA GβAGACGCCT GTβCTGCAGA CATTGATGGA 2520
GACGGTATCC TCAATGAACG GβACAACTGC CACTACGTCT ACAATGTGGA CCAGAGAGAC 2580
ACTGATATGβ ATGGGGTTGG AGATCAGTGT GACAATTGCC CCTTGGAACA CAATCCGGAT 2640
CAGCTGGACT CTGACTCAGA CCGCATTGGA GATACCTGTG ACAACAATCA GGATATTGAT 2700
GAAGATGGCC ACCAGAACAA TCTGGACAAC TGTCCCTATG TGCCCAATGC CAACCAGGCT 2760
GACCATGACA AAGATGGCAA GGGAGATGCC TGTGACCACG ATGATGACAA CGATGGCATT 2820
CCTGATGACA AGGACAACTG CAGACTCGTG CCCAATCCCG ACCAGAAGGA CTCTGACGGC 2880
GATGGTCGAG GTGATGCCTG CAAAGATGAT TTTGACCATG ACAGTGTGCC AGACATCGAT 2940
GACATCTβTC CTGAGAATGT TGACATCAGT GAGACCGATT TCCGCCGATT CCAGATGATT 3000
CCTCTGGACC CCAAAGGGAC ATCCCAAAAT GACCCTAACT GGGTTGTACG CCATCAGGGT 3060
AAAGAACTCG TCCAGACTGT CAACTGTGAT CCTGGACTCG CTGTAGGTTA TGATGAGTTT 3120
AATGCTGTGG ACTTCAGTGG CACCTTCTTC ATCAACACCG AAAGGGACGA TGACTATGCT 3180
GGATTTGTCT TTGGCTACCA GTCCAGCAGC CGCTTTTATG TTGTGATGTG GAAGCAAβTC 3240
ACCCAGTCCT ACTGGGACAC CAACCCCACG AGGGCTCAGG GATACTCGGG CCTTTCTGTG 3300
AAAGTTGTAA ACTCCACCAC AGGGCCTGGC GAGCACCTGC GGAACGCCCT GTGGCACACA 3360
GGAAACACCC CTGGCCAGGT GCGCACCCTG TGGCATGACC CTCGTCACAT AGGCTGGAAA 3420
GATTTCACCG CCTACAGATG GCGTCTCAGC CACAGGCCAA AGACGGGTTT CATTAGAGTG 3480
GTGATGTATG AAGGGAAGAA AATCATGGCT GACTCAGGAC CCATCTATGA TAAAACCTAT 3540
GCTGGTGGTA GACTAGGGTT GTTTGTCTTC TCTCAAGAAA TGGTGTTCTT CTCTGACCTG 3600
AAATACGAAT GTAGAGATCC CTAATCATCA AATTGTTGAT TGAAAGACTG ATCATAAACC 3660
AATGCTGGTA TTGCACCTTC TGGAACTATG GGCTTGAGAA AACCCCCAGG ATCACTTCTC 3720
CTTGGCTTCC TTCTTTTCTG TGCTTGCATC AGTGT6GACT CCTAGAACGT GCGACCTGCC 3780
TCAACAAAAT βCAGTTTTCA AAAACAGACT CATCAGCATT CAGCCTCCAA TβAATAAGAC 3840
ATCTTCCAAG CATATAAACA ATTGCTTTGG TTTCCTTTTG AAAAAGCATC TACTTGCTTC 3900
AGTTGGGAAG GTGCCCATTC CACTCTGCCT TTGTCACAGA GCAGGβTGCT ATTGTGAGGC 3960
CATCTCT 3967
Seq ID NO: C7 DNA Sequence
Nucleic Acid Accession #: NM_002192
Coding sequence: 86..1366
1 11 21 31 41 51
I I I I I I
TCCACACACA CAAAAAACCT GCGCGTGAGG GGGGAGGAAA AGCAGββCCT TTAAAAAGGC 60
AATCACAACA ACTTTTGCTG CCAGGATGCC CTTβCTTTβG CTGAGAGGAT TTCTGTTGGC 120
AAGTTGCTGG ATTATAGTGA GGAGTTCCCC CACCCCAGGA TCCGAGGGGC ACAGCGCGGC 180
CCCCGACTGT CCGTCCTGTG CGCTGGCCGC CCTCCCAAAG GATGTACCCA ACTCTCAGCC 240
AGAGATGGTG GAGGCCGTCA AGAAGCACAT TTTAAACATG CTGCACTTGA AGAAGAGACC 300
CGATGTCACC CAGCCGGTAC CCAAGGCGGC GCTTCTGAAC GCGATCAGAA AGCTTCATβT 360
GGGCAAAGTC GβGGAGAACG GGTATGTGGA GATAGAGGAT GACATTGGAA GβAGGGCAGA 420
AATGAATGAA CTTATGGAGC AGACCTCGGA GATCATCACG TTTGCCGAGT CAGGAACAGC 480
CAGGAAGACG CTGCACTTCG AGATTTCCAA GGAAGGCAGT GACCTGTCAG TβGTGGAGCG 540
TGCAβAAGTC TGGCTCTTCC TAAAAGTCCC CAAGGCCAAC AGGACCAGGA CCAAAGTCAC 600
CATCCGCCTC TTCCAGCAGC AGAAGCACCC GCAβGGCAGC TTβGACACAG GGGAAGAGGC 660
CGAGGAAβTβ GGCTTAAAGG GGGAGAGGAG TGAACTGTTG CTCTCTGAAA AAGTAGTAGA 720
CGCTCGGAAG AGCACCTGGC ATGTCTTCCC TGTCTCCAGC AGCATCCAGC GGTTGCTβGA 780
CCAGGGCAAG AGCTCCCTGG ACGTTCGGAT TGCCTGTGAG CAGTGCCAGG AGAGTGGCGC 840
CAGCTTGGTT CTCCTGGGCA AGAAGAAGAA GAAAGAAGAG GAGGGGGAAG GβAAAAAGAA 900
GGGCGGAGGT βAAGGTGGGG CAGGAGCAGA TGAGGAAAAG GAGCAGTCGC ACAGACCTTT 960
CCTCATGCTβ CAGGCCCGGC AGTCT6AAGA CCACCCTCAT CGCCGGCGTC GGCGGGGCTT 1020 GGAGTGTGAT GGCAAGGTCA ACATCTGCTG TAAGAAACAG TTCTTTGTCA GTTTCAAGGA 1080 CATCGβCTGG AATGACTGGA TCATTβCTCC CTCTβCCTAT CATGCCAACT ACTGCGAGGG 1140 TGAGTGCCCG AGCCATATAG CAGGCACGTC CGGGTCCTCA CTGTCCTTCC ACTCAACAGT 1200 CATCAACCAC TACCGCATGC GGGGCCATAG CCCCTTTGCC AACCTCAAAT CGTGCTGTGT 1260 GCCCACCAAG CTGAGACCCA TGTCCATCTT GTACTATGAT CATGGTCAAA ACATCATCAA 1320 AAAGGACATT CAGAACATGA TCGTGGAGGA GTGTGGGTGC TCATAGAGTT GCCCAGCCCA 1380 GGGGGAAAβG GAGCAAGAGT TGTCCAGAGA AGACAGTGGC AAAATGAAGA AATTTTTAAG 1440 GTTTCTβAGT TAACCAGAAA AATAGAAATT AAAAACAAAA CAAAACAAAA AAAAAAACAA 1500 AAAAAAACAA AAGTAAATTA AAAACAAACC TGATGAAACA GATGAAACAG ATGAAGGAAG 1560 ATGTGGAAAT CTTAGCCTβC CTTAβCCAGG GCTCAGAGAT GAAGCAGTGA AGAGACAGAT 1620 TGGGAGGGAA AGGGAGAATG GTGTACCCTT TATTTCTTCT GAAATCACAC TGATGACATC 1680 AGTTGTTTAA ACGGGGTATT GTCCTTTCCC CCCTTGAGGT TCCCTTGTGA GCTTGAATCA 1740 ACCAATCTGA TCTGCAGTAG TGTGβACTAG AACAACCCAA ATAGCATCTA GAAAGCCATG 1800 AGTTTGAAAG GGCCCATCAC AGGCACTTTC CTAGCCTAAT 1840
Seq ID NO: C8 DNA Sequence
Nucleic Acid Accession ff : NM_000095.1
Coding sequence : 26. .2299
11 21 31
CAGCACCCAG CTCCCCGCCA CCGCCATGGT CCCCGACACC GCCTGCGTTC TTCTGCTCAC 60
CCTGGCTGCC CTCGGCGCGT CCGGACAGGG CCAGAGCCCG TTGGGCTCAG ACCTGGGCCC 120
GCAGATGCTT CGGGAACTGC AGGAAACCAA CGCGGCGCTG CAGGACGTGC GGGACTGGCT 180
GCGGCAGCAG βTCAGGGAGA TCACGTTCCT GAAAAACACG GTGATGGAGT GTGACGCGTG 240
CGGGATGCAG CAGTCAGTAC GCACCGGCCT ACCCAGCGTG CGGCCCCTGC TCCACTGCGC 300
GCCCGGCTTC TGCTTCCCCG GCGTGβCCTG CATCCAGACG GAGAGCGGCG GCCGCTGCGG 360
CCCCTGCCCC GCGGGCTTCA CGGGCAACGG CTCGCACTGC ACCGACGTCA ACGAGTGCAA 420
CGCCCACCCC TGCTTCCCCG GAGTCCGCTG TATCAACACC AGCCCβGGGT TCCGCTGCGA 480
GGCTTGCCCG CCGGG6TACA GCGGCCCCAC CCACCAGGGC GTGGGGCTGG CTTTCGCCAA 540
GGCCAACAAG CAGGTTTGCA CGGACATCAA CGAGTGTGAG ACCGGGCAAC ATAACTGCGT 600
CCCCAACTCC GTGTβCATCA ACACCCGβGG CTCCTTCCAG TGCGGCCCGT GCCAGCCCGG 660
CTTCGTGGGC GACCAGGCGT CCGGCTGCCA GCGCGGCGCA CAGCGCTTCT GCCCCGACGG 720
CTCGCCCAGC GAGTGCCACβ AGCATGCAGA CTGCGTCCTA GAGCGCGATG GCTCGCGGTC 780
GTGCGTGTGT CGCGTTGGCT GGGCCGGCAA CGββATCCTC TGTGGTCGCG ACACTGACCT 840
AGACGGCTTC CCGGACGAGA AGCTGCGCTG CCCGGAGCCG CAGTGCCGTA AGGACAACTG 900
CGTGACTGTG CCCAACTCAG βGCAGGAGGA TGTGGACCGC GATGGCATCG GAGACGCCTG 960
CGATCCGGAT GCCGACGGGG ACGGGGTCCC CAATGAAAAG GACAACTGCC CGCTGGTGCG 1020
GAACCCAGAC CAGCGCAACA CGGACGAGGA CAAGTGGGGC GATGCGTGCG ACAACTGCCG 1080
GTCCCAGAAG AACGACGACC AAAAGGACAC AGACCAGGAC GGCCGGGGCG ATGCGTGCGA 1140
CGACGACATC GACGGCGACC GGATCCGCAA CCAGGCCGAC AACTGCCCTA GβGTACCCAA 1200
CTCACACCAG AAGGACAGTG ATGGCGATGG TATAGGGGAT GCCTGTGACA ACTGTCCCCA 1260
GAAGAGCAAC CCGGATCAGβ CGGATGTGGA CCACGACTTT GTGG6AGATG CTTGTGACAG 1320
CGATCAAGAC CACGATGGAG ACGβACATCA GGACTCTCGG GACAACTGTC CCACGGTGCC 1380
TAACAGTGCC CAGGAGGACT CAβACCACGA TGGCCAGGGT GATGCCTGCG ACGACGACGA 1440
CGACAATGAC GGAGTCCCTG ACAβTCGGGA CAACTGCCGC CTGGTGCCTA ACCCCGGCCA 1500
GGAGGACGCG GACAGGGACG GCGTGGGCGA CGTGTGCCAG GACGACTTTG ATGCAGACAA 1560
GGTGGTAGAC AAGATCGACG TGTGTCCGGA GAACGCTGAA GTCACGCTCA CCGACTTCAG 1620
GGCCTTCCAβ ACAGTCGTGC TGGACCCGGA GGβTGACGCC CAGATTGACC CCAACTGGGT 1680
GGTGCTCAAC CAGGβAAGGβ AGATCGTGCA GACAATGAAC AGCGACCCAG GCCTGGCTGT 1740
GGGTTACACT GCCTTCAATβ GCGTGGACTT CGAGGGCACG TTCCATGTGA ACACGGTCAC 1800
GGATGACGAC TATGCGGGCT TCATCTTTGG CTACCAGGAC AGCTCCAGCT TCTACGTGGT 1860
CATGTGGAAG CAGATGGAGC AAACGTATTG GCAGGCGAAC CCCTTCCGTG CTGTGGCCGA 1920
GCCTGGCATC CAACTCAAGG CTGTGAAGTC TTCCACAββC CCCGGGGAAC AGCTGCGGAA 1980
CGCTCTGTGG CATACAGGAG ACACAGAGTC CCAGGTGCGG CTGCTGTGGA AGGACCCGCG 2040
AAACGTGGGT TββAAGGACA AGAAGTCCTA TCGTTGGTTC CTGCAGCACC GGCCCCAAGT 2100
GGGCTACATC AβGGTGCGAT TCTATGAGGG CCCTGAGCTG GTGβCCGACA GCAACGTGGT 2160
CTTGGACACA ACCATGCGGβ GTGGCCGCCT GGGGGTCTTC TGCTTCTCCC AGGAGAACAT 2220
CATCTGGGCC AACCTCCGTT ACCGCTβCAA TGACACCATC CCAGA6GACT ATGAGACCCA 2280
TCAGCTGCGG CAAGCCTAGG GACCAGββTG AGGACCCGCC GGATGACAGC CACCCTCACC 2340
GCGGCTGGAT GGGGGCTCTG CACCCAGCCG AAGGGGTGGC CGTCCTGAGG GGGAAGT6AG 2400
AAGGGCTCAG AGAGGACAAA ATAAAGTGTG TGTGCAGGG 2439
Seq ID NO: C9 DNA Sequence
Nucleic Acid Accession # : XM_057014
Coding sequence : 143 . .874
11 21 31 41 51
GβGAββGAGA GAGGCGCGCG GGTGAAAGGC GCATTGATGC AGCCTGCGGC GGCCTCGGAG 60 C6CGGCGGAG CCAGACGCTG ACCACGTTCC TCTccTceβT CTCCTCCGCC TCCAGCTCCG 120 CGCTGCCCGG CAGCCGGGAG CCATGCGACC CCAGGGCCCC GCCβCCTCCC CGCAGCGGCT 180 CCGCGGCCTC CTGCTGCTCC TGCTGCTGCA GCTGCCCGCβ CCGTCGAGCG CCTCTβAGAT 240 CCCCAAGGGG AAGCAAAAGG CGCAGCTCCG βCAGAGGGAβ GTGGTGGACC TGTATAATGG 300 AATGTGCTTA CAAGβGCCAG CAGGAGTGCC TGGTCGAGAC GGGAGCCCTG GGGCCAATGG 360 CATTCCGGGT ACACCTGGGA TCCCAGGTCG CβATGGATTC AAAGGAGAAA AGGGGGAATG 420 TCTGAGGGAA AGCTTTGAGβ AGTCCTGGAC ACCCAACTAC AAGCAGTGTT CATGGAGTTC 480 ATTGAATTAT GGCATAGATC TTGβGAAAAT TGCGGAGTβT ACATTTACAA AGATβCGTTC 540 AAATAGTGCT CTAAGAGTTT TGTTCAGTGG CTCACTTCGG CTAAAATGCA GAAATGCATG 600 CTGTCAGCGT TGGTATTTCA CATTCAATGG AGCTGAATGT TCAGGACCTC TTCCCATTGA 660 AGCTATAATT TATTTGGACC AAGGAAGCCC TGAAATGAAT TCAACAATTA ATATTCATCG 720 CACTTCTTCT GTGGAAGGAC TTTGTGAAGβ AATTGGTGCT GGATTAGTGG ATGTTGCTAT 780
CTGGGTTGGC ACTTGTTCAG ATTACCCAAA AGGAGATGCT TCTACTGGAT GGAATTCAGT 840
TTCTCGCATC ATTATTGAAG AACTACCAAA ATAAATGCTT TAATTTTCAT TTGCTACCTC 900
TTTTTTTATT ATGCCTTGGA ATGβTTCACT TAAATGACAT TTTAAATAAG TTTATGTATA 960
CATCTGAATG AAAAGCAAAβ CTAAATATGT TTACAGACCA AAGTGTGATT TCACACTGTT 1020
TTTAAATCTA βCATTATTCA TTTTGCTTCA ATCAAAAGTG GTTTCAATAT TTTTTTTAGT 1080
TGGTTAGAAT ACTTTCTTCA TAGTCACATT CTCTCAACCT ATAATTTGGA ATATTGTTGT 1140
GGTCTTTTGT TTTTTCTCTT AGTATAGCAT TTTTAAAAAA ATATAAAAGC TACCAATCTT 1200
TGTACAATTT GTAAATGTTA AGAATTTTTT TTATATCTGT TAAATAAAAA TTATTTCCAA 1260
CAACCTTAAA AAAAAAAAAA AAAA 1284
Seq ID NO: CIO DNA Sequence Nucleic Acid Accession #: NM.003225 Coding sequence: 41.*.295
1 11 21 31 41 51 1 1 1 I 1 J 1 | 1 | 1 ATCCCTGACT CGGGGTCGCC TTTGGAGCAG AGAGGAGGCA ATGGCCACCA TGGAGAACAA 60
GGTGATCTGC GCCCTGGTCC TGGTGTCCAT GCTGGCCCTC GGCACCCTGG CCGAGGCCCA 120
GACAGAGACG TGTACAGTGG CCCCCCGTGA AAGACAGAAT TGTGGTTTTC CTGGTGTCAC 180
GCCCTCCCAG TGTGCAAATA AGGGCTβCTβ TTTCGACGAC ACCGTTCGTG GGβTCCCCTG 240
GTGCTTCTAT CCTAATACCA TCβACβTCCC TCCAGAAGAβ GAGTGTGAAT TTTAGACACT 300
TCTGCAGGGA TCTGCCTGCA TCCTGACGGG GTGCCGTCCC CAGCACGGTG ATTAGTCCCA 360
GAGCTCGGCT GCCACCTCCA CCGGACACCT CAGACACGCT TCTGCAGCTG TGCCTCGGCT 420
CACAACACAG ATTβACTCCT CTGACTTTGA CTACTCAAAA TTGGCCTAAA AATTAAAAβA 480
GATCGATATT AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 540
Seq ID NO: Cll DNA Sequence
Nucleic Acid Accession # : NM.015419.1
Coding sequence: 1. .8487
11 21 31
ATGCCCAAGC GCGCGCACTG GβeeecccTc TCCGTGGTGC TGATCCTGCT TTβGGGCCAT 60
CCGCGAGTGβ CGCTGGCCTG CCCGCATCCT TGTGCCTGCT ACGTCCCCAG CGAβGTCCAC 120
TGCACGTTCC GATCCCTGGC TTCCGTGCCC GCTGGCATTG CTAGACACGT GβAAAGAATC 180
AATTTGGGGT TTAATAGCAT ACAGGCCCTG TCAGAAACCT CATTTGCAGG ACTCACCAAG 240
TTGGAGCTAC TTATGATTCA CGGCAATGAG ATCCCAAGCA TCCCCGATGG AGCTTTAAGA 300
GACCTCAGCT CTCTTCAGGT TTTCAAGTTC AGCTACAACA AGCTGAGAGT GATCACAGGA 360
CAGACCCTCC AGGGTCTCTC TAACTTAATG AββCTβCACA TTGACCACAA CAAGATCGAG 420
TTTATCCACC CTCAAGCTTT CAACGβCTTA ACGTCTCTβA GGCTACTCCA TTTGGAAGGA 480
AATCTCCTCC ACCAGCTGCA CCCCA6CACC TTCTCCACGT TCACATTTTT GGATTATTTC 540
AGACTCTCCA CCATAAGGCA CCTCTACTTA GCAGAGAACA TGGTTAGAAC TCTTCCTGCC 600
AGCATGCTTC GGAACATGCC GCTTCTGGAβ AATCTTTACT TGCAGGGAAA TCCGTGGACC 660
TGCGATTGTG AGATGAGATG GTTTTTGGAA TGGGATGCAA AATCCAGAβG AATTCTGAAG 720
TGTAAAAAGG ACAAAGCTTA TGAAGGCGGT CAGTTGTGTG CAATGT6CTT CAGTCCAAAG 780
AAGTTGTACA AACATGAGAT ACACAAGCTG AAGGACATGA CTTGTCTGAA GCCTTCAATA 840
GAGTCCCCTC TGAGACAGAA CAGβAGCAGG AGTATTGAGG AGGAGCAAGA ACAGGAAGAG 900
GATGGTGGCA GCCAGCTCAT CCTββAGAAA TTCCAACTGC CCCAGTGGAG CATCTCTTTG 960
AATATGACCG ACGAGCACGG GAACATGGTβ AACTTGGTCT GTGACATCAA GAAACCAATG 1020
GATGTGTACA AGATTCACTT GAACCAAACG GATCCTCCAG ATATTGACAT AAATGCAACA 1080
CTTGCCTTGG ACTTTGAGTG TCCAATGACC CGAGAAAACT ATGAAAAGCT ATGβAAATTG 1140
ATAGCATACT ACAGTGAAGT TCCCGTGAAG CTACACAGAβ AGCTCATGCT CAGGAAAGAC 1200
CCCACAGTCA GCTACCAGTA CAGGCAGGAT GCTGATGAGG AAGCTCTTTA CTACACAGGT 1260
GTGAGAGCCC AGATTCTTGC AGAACCAGAA TGGGTCATGC AGCCATCCAT AGATATCCAG 1320
CTGAACCGAC GTCAGAGTAC GGCCAAGAAG GTβCTACTTT CCTACTACAC CCAGTATTCT 1380
CAAACAATAT CCACCAAAGA TACAAGGCAG GCTCGGGGCA GAAGCTGGGT AATGATTβAG 1440
CCTAGTGGAG CTGTGCAAAG AGATCAGACT GTCCTGGAAG GGGCTCCATG CCAGTTGAβC 1500
TGCAACGTβA AAGCTTCTGA GAGTCCATCT ATCTTCTGGG TGCTTCCAGA TGGCTCCATC 1560
CTGAAAGCGC CCATGGATGA CCCAGACAGC AAGTTCTCCA TTCTCAGCAG TGGCTGGCTG 1620
AGGATCAAGT CCATGGAGCC ATCTGACTCA GGCTTGTACC AGTGCATTGC TCAAGTGAGG 1680
GATGAAATGG ACCGCATGGT ATATAGGGTA CTTGTGCAGT CTCCCTCCAC TCAβCCAβCC 1740
GAGAAAGACA CAGTGACAAT TGβCAAGAAC CCAGGGGAGT CGβTGACATT GCCTTGCAAT 1800
GCTTTAGCAA TACCCGAAGC CCACCTTAGC TGGATTCTTC CAAACAGAAβ GATAATTAAT 1860
GATTTGGCTA ACACATCACA TGTATACATG TTGCCAAATG GAACTCTTTC CATCCCAAAG 1920
GTCCAAGTCA GTGATAGTGG TTACTACAGA TGTGTGGCTG TCAACCAGCA AβGGGCAGAC 1980
CATTTTACGG TGGGAATCAC AGTβACCAAG AAAGGGTCTG GCTTGCCATC CAAAAGAGGC 2040
AGACGCCCAG GTGCAAAGGC TCTTTCCAGA GTCAGAGAAG ACATCGTGGA GGATGAAGGG 2100
GGCTCGGGCA TGGGAGATGA AGAGAACACT TCAAGGAGAC TTCTGCATCC AAAGGACCAA 2160
GAGGTGTTCC TCAAAACAAA GGATGATGCC ATCAATGGAG ACAAGAAAGC CAAGAAAβGβ 2220
AGAAGAAAGC TGAAACTCTG GAAGCATTCG GAAAAAGAAC CACAGACCAA TGTTβCAGAA 2280
GGTCGCAGAG TGTTTGAATC TAGACGAAGG ATAAACATGG CAAACAAACA GATTAATCCG 2340
CAGCGCTGGG CTGATATTTT AGCCAAAGTC CGTGGGAAAA ATCTCCCTAA GGGCACAGAA 2400
GTACCCCCGT TGATTAAAAC CACAAGTCCT CCATCCTTGA GCCTAGAAGT CACACCACCT 2460
TTTCCTGCTG TTTCTCCCCC CTCAGCATCT CCTGTβCAGA CAGTAACCAG TGCTβAAβAA 2520
TCCTCAGCAG ATβTACCTCT ACTTGCTGAA GAAGAGCACG TTTTG6GTAC CATTTCCTCA 2580
GCCAGCATGG GGCTAGAACA CAACCACAAT GβAGTTATTC TTGTT6AACC TGAA6TAACA 2640
AGCACACCTC TGGAGGAAGT TGTT6ATGAC CTTTCT6AGA AGACTβAGGA βATAACTTCC 2700
ACTGAAGGAG ACCTGAAGGG GACAGCAGCC CCTACACTTA TATCTGAGCC TTATβAACCA 2760
TCTCCTACTC TGCACACATT AGACACAGTC TATGAAAAGC CCACCCATGA AGAGACGGCA 2820
ACAGAGGGTT GGTCTGCAGC AGATGTTGGA TCGTCACCAG AGCCCACATC CAGTGAGTAT 2880
GAGCCTCCAT TGGATGCTGT CTCCTTGGCT GAGTCTGAGC CCATGCAATA CTTTGACCCA 2940
GATTTGGAGA CTAAGTCACA ACCAGATGAG GATAAGATGA AAGAAGACAC CTTTGCACAC 3000
CTTACTCCAA CCCCCACCAT CTGGGTTAAT GACTCCAGTA CATCACAGTT ATTTGAGGAT 3060 TCTACTATAG GGGAACCAGG TGTCCCAGGC CAATCACATC TACAAGGACT GACAGACAAC 3120
ATCCACCTTG TGAAAAGTAG TCTAAGCACT CAAGACACCT TACTGATTAA AAAGGGTATG 3180
AAAGAGATβT CTCAGACACT ACAGGGAGGA AATATGCTAG AGGGAGACCC CACACACTCC 3240
AGAAβTTCTβ AβAGTGAGGG CCAAGAGAGC AAATCCATCA CTTTGCCTGA CTCCACACTG 3300
5 GGTATAATGA GCAGTATGTC TCCAGTTAAG AAGCCTGCGG AAACCACAGT TGGTACCCTC 3360
CTAGACAAAG ACACCACAAC AGTAACAACA ACACCAAGGC AAAAAβTTGC TCCGTCATCC 3420
ACCATGAGCA CTCACCCTTC TCGAAGGAGA CCCAACGGGA GAAββAGATT ACCCCCCAAC 3480
AAATTCCCCC ACCGGCACAA GCAAACCCCA CCCACAACTT TTGCCCCATC AGAGACTTTT 3540
TCTACTCAAC CAACTCAAGC ACCTGACATT AAGATTTCAA GTCAAGTGGA GAGTTCTCTG 3600 0 GTTCCTACAG CTTGGGTGGA TAACACAGTT AATACCCCCA AACAGTTGGA AATGGAGAAG 3660
AATGCAGAAC CCACATCCAA ββGAACACCA CGGAGAAAAC ACGGGAAGAG GCCAAACAAA 3720
CATCGATATA CCCCTTCTAC AGTGAGCTCA AGAGC6TCCG GATCCAAGCC CAGCCCTTCT 3780
CCAGAAAATA AACATAGAAA CATTGTTACT CCCAGTTCAG AAACTATACT TTTGCCTAGA 3840
ACTGTTTCTC TGAAAACTGA GGGCCCTTAT GATTCCTTAG ATTACATGAC AACCACCAGA 3900 5 AAAATATATT CATCTTACCC TAAAGTCCAA GAβACACTTC CAβTCACATA TAAACCCACA 3960
TCAGATGGAA AAGAAATTAA GGATGATGTT GCCACAAATG TTGACAAACA TAAAAGTGAC 4020
ATTTTAGTCA CTGGTGAATC AATTACTAAT GCCATACCAA CTTCTCGCTC CTTGGTCTCC 4080
ACTATGGGAG AATTTAAGGA AGAATCCTCT CCTGTAGGCT TTCCAGβAAC TCCAACCTGG 4140
AATCCCTCAA GβACGGCCCA GCCTGGGAGG CTACAGACAG ACATACCTGT TACCACTTCT 4200 0 GGGGAAAATC TTACAGACCC TCCCCTTCTT AAAGAGCTTG AGGATGTGGA TTTCACTTCC 4260
GAβTTTTTGT CCTCTTTGAC AGTCTCCACA CCATTTCACC AGGAAGAAGC TGGTTCTTCC 4320
ACAACTCTCT CAAGCATAAA AGTGGAGGTG GCTTCAAGTC AGGCAGAAAC CACCACCCTT 4380
GATCAAGATC ATCTTGAAAC CACTGTGGCT ATTCTCCTTT CTGAAACTAG ACCACAGAAT 4440
CACACCCCTA CTGCT6CCCG GATGAAGGAβ CCAGCATCCT CGTCCCCATC CACAATTCTC 4500 5 ATGTCTTTGG GACAAACCAC CACCACTAAG CCAGCACTTC CCAGTCCAAG AATATCTCAA 4560
GCATCTAGAβ ATTCCAAGGA AAATGTTTTC TTGAATTATG TGGGGAATCC AGAAACAGAA 4620
GCAACCCCAG TCAACAATGA AGGAACACAG CATATGTCAG GGCCAAATGA ATTATCAACA 4680
CCCTCTTCCG ACCGGGATGC ATTTAACTTG TCTACAAAGC TGGAATTGGA AAAGCAAGTA 4740
TTTGGTAGTA GGAGTCTACC ACGTGGCCCA GATAGCCAAC GCCAGβATGG AAGAGTTCAT 4800 0 GCTTCTCATC AACTAACCAG AGTCCCTCCC AAACCCATCC TACCAACAGC AACAGTGAGG 4860
CTACCTGAAA TGTCCACACA AAGCGCTTCC AGATACTTTG TAACTTCCCA GTCACCTCGT 4920
CACTGGACCA ACAAACCGGA AATAACTACA TATCCTTCTG βGGCTTTGCC AGAGAACAAA 4980
CAGTTTACAA CTCCAAGATT ATCAAGTACA ACAATTCCTC TCCCATTGCA CATGTCCAAA 5040
CCCAGCATTC CTAGTAAGTT TACTGACCGA AGAACTGACC AATTCAATGG TTACTCCAAA 5100 5 GTGTTTGGAA ATAACAACAT CCCTGAGGCA AGAAACCCAG TTGGAAAβCC TCCCAGTCCA 5160
AGAATTCCTC ATTATTCCAA TGGAAGACTC CCTTTCTTTA CCAACAAGAC TCTTTCTTTT 5220
CCACAGTTGG GAGTCACCCG GAGACCCCAG ATACCCACTT CTCCTCCGCC AGTAATGAGA 5280
GAGAGAAAAG TTATTCCAGG TTCCTACAAC AGGATACATT CCCATAGCAC CTTCCATCTG 5340
GACTTTGGCC CTCCGGCACC TGCGTTGTTG CACACTCCGC AGACCACGGG ATCACCCTCA 5400 0 ACTAACTTAC AGAATATCCC TATGGTCTCT TCCACCCAGA GTTCTATCTC CTTTATAACA 5460
TCTTCTGTCC AGTCCTCAGG AAGCTTCCAC CAGA6CAGCT CAAAGTTCTT TβCAGGAGGA 5520
CCTCCTGCAT CCAAATTCTG GTCTCTTGGG GAAAAβCCCC AAATCCTCAC CAAGTCCCCA 5580
CAGACTGTGT CCGTCACCGC TβAGACAGAC ACTGTGTTCC CCTGTGAGGC AACAGGAAAA 5640
CCAAAGCCTT TCGTTACTTG GACAAAGGTT TCCACAGGAG CTCTTATGAC TCCGAATACC 5700 5 AGβATACAAC GGTTTGAGGT TCTCAAGAAC GGTACCTTAG TGATACGGAA GGTTCAAGTA 5760
CAAGATCGAG GCCAGTATAT GTGCACCGCC AGCAACCTGC ACGGCCTGGA CAGβATββTβ 5820
GTCTTGCTTT CGGTCACCGT GCAβCAACCT CAAATCCTAG CCTCCCACTA CCAGβACGTC 5880
ACTGTCTACC TGGGAGACAC CATTGCAATG GAGTGTCTGG CCAAAGGGAC CCCAGCCCCC 5940
CAAATTTCCT GGATCTTCCC TGACAGGAGG GTGTββCAAA CTGTGTCCCC CGTβGAGAGC 6000
50 CGCATCACCC TGCACGAAAA CCGGACCCTT TCCATCAAGG AGGCGTCCTT CTCAβACAGA 6060
GGCGTCTATA ACTGCCTGGC CAGCAATGCA GCCGGGGCGG ACAGCCTβGC CATCCGCCTG 6120
CACGTβGCGG CACTGCCCCC CGTTATCCAC CAGGAGAAGC TGGAGAACAT CTCGCTGCCC 6180
CCGGGGCTCA GCATTCACAT TCACTGCACT GCCAAGGCTG CGCCCCTGCC CAGCGTGCGC 6240
TGGβTGCTCG GGGACGGTAC CCAGATCCGC CCCTCGCAGT TCCTCCACGG GAACTTGTTT 6300
55 GTTTTCCCCA ACGGGACGCT CTACATCCGC AACCTCGCGC CCAAGGACAG CGGGCGCTAT 6360
GAGTGCGTGG CCGCCAACCT GGTAGGCTCC GCGCGCAGGA CGGTGCAGCT GAACGTβCAG 6420
CGTGCAGCAG CCAACGCGCG CATCACGGGC ACCTCCCCGC GGAGβACGGA CGTCAGGTAC 6480
GGAGβAACCC TCAAGCTGGA CTGCAGCGCC TCGGGGGACC CCTGGCCGCG CATCCTCTGG 6540
- AGGCTGCCGT CCAAGAGGAT GATCGACGCG CTCTTCAGTT TTGATAGCAG AATCAAGβTG 6600
60 TTTGCCAATG GGACCCTGβT GGTGAAATCA GTGACGGACA AAGATGCCGβ AβATTACCTG 6660
TGCGTAGCTC GAAATAAGGT TGGTGATGAC TACGTGGTGC TCAAAGTββA TGTGGTGATG 6720
AAACCGGCCA AGATTGAACA CAAGGAGGAG AACGACCACA AAGTCTTCTA CGGGGGTGAC 6780
CTGAAAGTGG ACTGTGTGGC CACCGββCTT CCCAATCCCG AGATCTCCTG GAGCCTCCCA 6840
£ GACGGGAGTC TGGTGAACTC CTTCATGCAG TCGGATGACA GCGGTGGACG CACCAAGCGC 6900
65 TATβTCGTCT TCAACAATGG GACACTCTAC TTTAACGAAG TGGGGATGAG GβAGGAAGβA 6960 βACTACACCT βCTTTGCTGA AAATCAGGTC GGGAAGGACβ AGATGAGAGT CAβAβTCAAG 7020
GTGGTGACAG CGCCCGCCAC CATCCGGAAC AAGACTTACT TGGCGGTTCA GGTGCCCTAT 7080
GGAGACGTGG TCACTGTAGC CTGTGAGGCC AAAGGAGAAC CCATGCCCAA GGTGACTTGβ 7140
TTGTCCCCAA CCAACAAGGT GATCCCCACC TCCTCTGAGA AGTATCAGAT ATACCAAGAT 7200
70 βGCACTCTCC TTATTCAGAA AGCCCAGCCT TCTGACAGCG GCAACTACAC CTGCCTGGTC 7260
AGGAACAGCβ CGGGAGAGGA TAGGAAGACG GTGTGGATTC ACGTCAACβT CCAGCCACCC 7320
AAGATCAACG GTAACCCCAA CCCCATCACC ACCGTGCGGG AGATAGCAGC CGGGGGCAGT 7380
CGGAAACTGA TTGACTGCAA AGCTβAAGGC ATCCCCACCC CGAGGGTGTT ATGGGCTTTT 7440
CCCGAGGGTG TGGTTCTGCC AGCTCCATAC TATGβAAACC ββATCACTGT CCATGGCAAC 7500
75 GGTTCCCTGG ACATCAG6AG TTTGAGGAAG AGCGACTCCG TCCAGCTGGT ATGCATGGCA 7560
CGCAACGAGG GAGGGGAGGC GAGGTTGATC GTGCAGCTCA CTGTCCTGGA GCCCATGGAG 7620
AAACCCATCT TCCACGACCC GATCAGCGAG AAGATCACGG CCATGGCGGG CCACACCATC 7680
AGCCTCAACT GCTCTGCCGC GGGGACCCCG ACACCCAGCC TGGTGTGGGT CCTTCCCAAT 7740
GGCACCGATC TGCAβAGTGG ACAGCAβCTG CAGCGCTTCT ACCACAAGGC TGACGGCATG 7800
80 CTACACATTA GCGGTCTCTC CTCGGTGGAC GCTGGGGCCT ACCGCTGCGT GβCCCGCAAT 7860
GCCGCTGGCC ACACGGAGAG GCTGGTCTCC CTGAAGGTGG GACTGAAGCC AGAAGCAAAC 7920
AAGCAGTATC ATAACCTGGT CAGCATCATC AATGGTGAGA CCCTGAAGCT CCCCTGCACC 7980
CCTCCCGGGG CTGGGCAGGG ACGTTTCTCC TGGACGCTCC CCAATGGCAT GCATCTGGAG 8040
GGCCCCCAAA CCCTGGGACG CGTTTCTCTT CTGGACAATG GCACCCTCAC GGTTCβTGAG 8100 GCCTCGGTGT TTGACAGGββ TACCTATGTA TGCAGGATGG AGACGGAGTA CGGCCCTTCG 8160
GTCACCAGCA TCCCCGTGAT TGTGATCβCC TATCCTCCCC GβATCACCAβ CβAGCCCACC 8220
CCGGTCATCT ACACCCGGCC CGGGAACACC GTGAAACTβA ACTGCATGGC TATGGGGATT 8280
CCCAAAGCTG ACATCACGTG GGAGTTACCG βATAAGTCGC ATCTGAAβGC AGGGβTTCAG 8340
GCTCGTCTGT ATGGAAACAG ATTTCTTCAC CCCCAGGGAT CACTGACCAT CCAGCATGCC 8400
ACACA6AGAG ATGCCGGCTT CTACAAGTGC ATGGCAAAAA ACATTCTCGG CAGTGACTCC 8460
AAAACAACTT ACATCCACGT CTTCTβAAAT GTGGATTCCA GAATGATTGC TTAGGAACTG 8520
ACAACAAAGC GGGGTTTGTA AGGGAAGCCA GβTTββββAA TAGGAGCTCT TAAATAATGT 8580 βTCACAβTβC ATGGTGGCCT CTGGTGGGTT TCAAβTTGAG GTTGATCTTβ ATCTACAATT 8640
GTTGGGAAAA GGAAGCAATG CAGACACGAG AAGGAGGGCT CAGCCTTGCT βAGACACTTT 8700
CTTTTGTβTT TACATCATGC CAGGGGCTTC ATTCAGGGTG TCTGTGCTCT CACTβCAATT 8760
TTTCTTCTTT TGCAAATGCC ACTCGACTGC CTTCATAAGC GTCCATAGGA TATCTβAββA 8820
ACATTCATCA AAAATAAGCC ATAGACATGA ACAACACCTC ACTACCCCAT TGAAGACGCA 8880
TCACCTAβTT AACCTGCTGC AGTTTTTACA TGATAGACTT TGTTCCAGAT TGACAAGTCA 8940
TCTTTCAGTT ATTTCCTCTG TCACTTCAAA ACTCCAGCTT GCCCAATAAG GATTTAGAAC 9000
CACAGTGACT GATATATATA TATATATTTT AATTCAGAGT TACATACATA CAGCTACCAT 9060
TTTATATGAA AAAAGAAAAA CATTTCTTCC TGGAACTCAC TTTTTATATA ATGTTTTATA 9120
TATATATTTT TTCCTTTCAA ATCAGACGAT GAGACTAGAA GGAGAAATAC TTTCTGTCTT 9180
ATTAAAATTA ATAAATTATT GGTCTTTACA AGACTTGGAT ACATTACAGC AGACATGGAA 9240
ATATAATTTT AAAAAATTTC TCTCCAACCT CCTTCAAATT CAGTCACCAC TGTTATATTA 9300
CCTTCTCCAG GAACCCTCCA GTββGβAAGG CTGCGATATT AGATTTCCTT GTATGCAAAG 9360
TTTTTGTTGA AAGCTGTGCT CAGAGGAGGT GAGAGGAGAβ GAAGGAGAAA ACTGCATCAT 9420
AACTTTACAG AATTGAATCT AGAGTCTTCC CCGAAAAGCC CAGAAACTTC TCTGCAGTAT 9480
CTGGCTTGTC CATCTGGTCT AAGGTGGCTG CTTCTTCCCC AGCCATGAGT CAGTTTGTGC 9540
CCATGAATAA TACACGACCT GTTATTTCCA TGACTGCTTT ACTGTATTTT TAAGβTCAAT 9600
ATACTGTACA TTTGATAATA AAATAATATT CTCCCAAAAA AAAAA 9645
Seq ID NO: C12 DNA Sequence Nucleic Acid Accession ff : AK001903 Coding sequence : none
60
120
Figure imgf001206_0001
180
AGATGGTCAA GGCCATGGAA AAAGCAGAAA TTTACCAAGA AAGCTGATAC CCATGTATAG 240
TTCCCACTCA TCTCAAATAC ATCTGCTATC TTTTTAAGCT AAGTCCTAGA GATATCGGGG 300
ATAACATβββ GGTTGATTAG TGACCACAGT TATCAGAAGC AGAGAAATGT AATTCCATAT 360
TTTATTTβAA ACTTATTCCA TATTTTAATT GGATATTGAG TGATTGGGTT ATCAAACACC 420
CACAAACTTT AATTTTGTTA AATTTATATG GCTTTGAAAT AGAAGTATAA GTTGCTACCA 480
TTTTTT6ATA ACATTGAAAG ATAGTATTTT ACCATCTTTA ATCATCTTGG AAAATACAAG 540
TCCTGTGAAC AACCACTCTT TCACCTAGCA GCATGAGGCC AAAAGTAAAG GCTTTAAATT 600
ATAACATATG GGATTCTTAG TAGTATGTTT TTTTCTTGAA ACTCAβTGGC TCTATCTAAC 660
CTTACTATCT CCTCACTCTT TCTCTAAGAC TAAACTCTAG GCTCTTAAAA ATCTGCCCAC 720
ACCAATCTTA GAAGCTCTGA AAAGAATTTG TCTTTAAATA TCTTTTAATA GTAACATGTA 780
TTTTATGGAC GAAATTGACA TTTTCGACTA TTTTTTCCAA AAAAGTCAGG TGAATTTCAG 840
CACACTGAGT TGGGAATTTC TTATCCCAGA AGACCAACCA ATTTCATATT TATTTAAGAT 900
TβATTCCATA CTCCGTTTTC AAββAβAATC CCTGCAGTCT CCTTAAAG6T AGAACAAATA 960
CTTTCTATTT TTTTTTTCAC CATTGTGβGA TTGGACTTTA AGAGGTGACT CTAAAAAAAC 1020
AβAβAACAAA TATGTCTCAG TTGTATTAAG CACGGACCCA TATTATCATA TTCACTTAAA 1080
AAAATGATTT CCTGTGCACC TTTTGGCAAC TTCTCTTTTC AATGTAGGGA AAAACTTAGT 1140
CACCCTGAAA ACCCACAAAA TAAATAAAAC TTGTAGATGT GGGCAGAAGG TTTGGGGGTG 1200
GACATTGTAT GTGTTTAAAT TAAACCCTGT ATCACTGAGA AGCTGTTGTA TGGGTCAGAG 1260
AAAATGAATG CTTAGAAGCT GTTCACATCT TCAAGAβCAβ AAGCAAACCA CATGTCTCAG 1320
CTATATTATT ATTTATTTTT TATGCATAAA GTGAATCATT TCTTCTGTAT TAATTTCCAA 1380
AGGGTTTTAC CCTCTATTTA AATGCTTTGA AAAACAGTGC ATTGACAATG GGTTGATATT 1440
TTTCTTTAAA AGAAAAATAT AATTATGAAA GCCAAGATAA TCTGAAGCCT GTTTTATTTT 1500
AAAACTTTTT ATGTTCTGTG GTTGATGTTG TTTGTTTβTT TGTTTCTATT TTGTTGGTTT 1560
TTTACTTTGT TTTTTGTTTT GTTTTGTTTT GTTTTGCATA CTACATGCAG TTCTTTAACC 1620
AATGTCTGTT TGGCTAATβT AATTAAAGTT GTTAATTTAT ATGAGTGCAT TTCAACTATG 1680
TCAATGGTTT CTTAATATTT ATTGTGTAGA AGTACTGGTA ATTTTTTTAT TTACAATATG 1740
TTTAAAβAβA TAACAGTTTG ATATGTTTTC ATGTGTTTAT AGCAGAAGTT ATTTATTTCT 1800
ATGGCATTCC AGCGGATATT TTGGTGTTTG CGAGGCATβC AGTCAATATT TTGTACAGTT 1860
AGTGGACAGT ATTCAGCAAC GCCTGATAGC TTCTTTGGCC TTATGTTAAA TAAAAAGACC 1920
TGTTTGGGAT GT 1932 Seq ID NO : C13 Protein Sequence
Nucleic Acid Accession ff : Eos sequence Coding sequence : 1. .5001
60
120
Figure imgf001206_0002
180
TCAAGACAGT ACACCGTGCG CTATCGAGAG AAGGGGGAAT TGGCCAGGTG GGATTATAAG 240
CAGATCβCTA ACAGGCGTGT GCTGATTGAG AACCTGATTC CAGACACTGT GTATGAATTT 300
GCAGTCCGTA TTTCACAGGβ TGAAAGAGAT GGCAAATGGA GTACGTCAβT CTTCCAAAβA 360
ACACCAGAAT CTGCCCCTAC CACAGCTCCT GAAAACTTGA ACGTCTGGCC AGTCAATGGC 420
AAACCTACAG TTGTCGCTβC ATCTTGGGAT GCGCTACCAG AGACTGAGGG GAAAGTGAAA 480
GTCTGTCTGC TGGACACAGG ACTGTTTTCA GTTTCCTCCT TCCAACCATC TGCCAAATCA 540 TTTCAGAATA CATTCTTTCA TACGCCCCGG CTCTCAAACC ATTTGGAGCA AAGTCCCTCA 600
CCTATCCTGG AGACACTACT TCTGCCCTGG TGGATGGTCT GCAGCCTGGG GAACGCTATC 660
TTTTCAAAAT CCGGGCCACA AACAGGAGAG GCCTGGGACC TCACTCCAAA GCCTTCATTG 720
TCGCTATGCC AACAAGAATG CAGCTGTACC CAGAAGGATT TCAGTTGTCT AGCTTACCTG 780
ATCGATATCC AAACCAAACA AGTTAATAAA GATCCACAAC TGGAAGGGAG TGTTTTTGGA 840
CCATGTTTTC TTTTCTACTT CCTCACATTT ATGCTGGATA TTGGCGGCTT TTCCTTCATT 900
ATGTGCTATG AAGACCCANN TGTTTCTTCT TTGACAGGCA ATTCTTTAAA ATCTGTTGCA 960
GCCAGTAAGG CGGATGTTCA GCAGAACACG GAGGACAATG GGAAACCCGA AAAACCTGAG 1020
CCTTCCTCAC CTTCTCCCAG AGCTCCAGCT TCCTCCCAAC ACCCCTCTGT GCCTGCTTCT 1080
CCCCAAGGGA GAAATGCCAA GGACCTTCTT CTTGACTTGA AGAACAAAAT ATTGGCTAAT 1140
GGTGGGGCGC CCCGAAAACC CCAGCTTCGC GCCAAGAAGG CAGAGGAGCT GGATCTTCAG 1200
TCGACAGAAA TCACTGGGGA GGAββAGCTG GGTTCCCGGβ AGGACTCGCC CATGTCACCC 1260
TCAGACACCC AAGACCAGAA ACGGACCCTG AGGCCGCCAA GTAGACACGG CCACTCGGTG 1320
GTTGCTCCCG GCAGGACTGC AGTGAGGGCC CGGATβCCAG CGCTGCCCCG AAGGGAAGGC 1380
GTAGATAAGC CTGGCTTTTC CCTGGCCACG CAGCCCCβCC CAGGGGCGCC CCCCTCGGCT 1440
TCGGCCTCTC CTGCCCACCA CGCGTCCACC CAGGGCACCT CTCATCGTCC TTCCCTGCCT 1500
GCCAGCTTGA ATGACAACGA CTTGGTGGAC TCAGACβAAG ATGAGCGCGC TGTGGGCTCC 1560
CTCCACCCCA AGGGCGCCTT CGCCCAGCCC CGGCCAGCCC TGTCCCCCAG CCGCCAβTCC 1620
CCGTCCAGCG TTCTCCGCGA CAGAAGCTCT GTGCACCCCG GCGCAAAGCC AGCCTCGCCG 1680
GCGCGβAGGA CCCCCCATTC AGGGGCCGGA GAβGAAGATT CCAGTGCCTC AGCCCCACCC 1740
TCAAGACTTT CTCCACCCCA TGGGGGATCA TCTCGGCTGC TGCCCACCCA GCCACACCTG 1800
AGCTCTCCAC TTTCCAAGGG CGGGAAGGAT GβTGAGGACG CCCCAGCCAC CAACTCCAAT 1860
GCGCCATCAC βGTCCACCAT βTCCTCCTCC GTCTCTTCTC ATCTCTCGTC CAGGACGCAG 1920
GTCTCTGAGG GAGCGGAGGC TTCTGATGGT GAAAGCCACG GTGACGGCGA TAGGGAAGAC 1980
GGCGGAAGGC AGGCCβAGGC CACGGCCCAG ACGCTGCGGG CCCGGCCTGC CTCTGGACAC 2040
TTCCATTTGC TCAGACACAA ACCCTTTGCT GCCAACGGGA GGTCTCCAAG CAGGTTCAGC 2100
ATTGGGCGGG GACCTCGGCT GCAGCCCTCC AGCTCCCCAC AGTCβACTβT GCCCTCCCGA 2160
GCCCAGCCCA GGGTTCCCTC TCACTCTGAT TCCCACCCTA AGCTTAGCTC AGGTATCCAT 2220
GGAGACGAGG AGGATGAGAA GCCGCTTCCT GCCACCGTTβ TCAATGACCA CGTβCCTTCC 2280
TCCTCCAGGC AGCCCATCTC CCGGGGCTGG GAGGACTTAA GGAGAAGCCC GCAGAβAGGG 2340
GCCAGCCTGC ATCGGAAGGA ACCCATCCCA GAGAACCCCA AATCCACAGG GGCAGATACA 2400
CATCCTCAGG GCAAGTACTC CTCCCTGGCC TCCAAGGCTC AGGATGTTCA ACAGAGCACA 2460
GACGCβGACA CGGAGGGTCA TTCTCCCAAA GCACAGCCAG GGTCCACAGA CCGCCACGCG 2520
TCCCCTGCTC GTCCTCCC6C AGCACGGTCA CAGCAβCATC CCAGTGTTCC CAGAAGGATG 2580
ACACCCGGCC GGGCCCCAGA ACAGCAGCCC CCTCCTCCCG TCGCCACGTC CCAGCACCAC 2640
CCGGGACCCC AGAGCAGAGA CGCGGGTCGG TCACCTTCCC AGCCCAGGCT CTCACTGACC 2700
CAGGCCGGGC GGCCCCGCCC CACGTCGCAG GGCCGCTCCC ACTCCTCCTC GβACCCTTAC 2760
ACGGCGAβCT CCAGAGGGAT GCTCCCCACG GCCCTCCAGA ACCAGGACGA GGATGCCCAG 2820
GGCAGCTACG ACGACGACAG CACAGAAGTC GAGGCCCAGG ATGTGCGGGC CCCCGCCCAC 2880
CCCGCGCGCG CCAAGGAGGC AGCTGCGTCC CTTCCCAAGC ACCAGCAGGT GGAGTCTCCC 2940
ACAGGCβCAβ GGGCAGGTGG CGACCACAGG TCCCAGCGCG GACATGCGGC CTCCCCCGCC 3000
AGGCCCAGCC GACCCGGCGG CCCCCAGTCC CGCCCCCGGG TCCCCAGCAG ββCAGCGCCG 3060
GGGAAGTCGG AGCCTCCTTC CAAGCGGCCC CTGTCCTCCA AGTCCCAGCA GTCGGTCTCA 3120
GCCGAGGACG AGGAGGAGGA GGACGCGGGG TTTTTTAAAG GCGGGAAAGA AGACCTTCTG 3180
TCTTCCTCTG TGCCAAAGTG GCCCTCTTCC TCCACTCCCA GGGβCGβCAA AGACGCCGAT 3240
GGGAGCCTCG CCAAG6AAGA GAGGGAGCCT GCCATCGCGC TTGCCCCTCG CGGAGGGAGC 3300
CTGGCTCCTG TGAAGCGACC TCTCCCCCCA CCTCCAGGCA GCTCCCCCAG GGCCTCCCAC 3360
GTCCCTTCCC GACCGCCCCC TCGCAGCGCT βCCACCGTGA GCCCCGTCβC GβGCACCCAC 3420
CCCTGGCCGC GGTACACCAC GCGCGCCCCV CCTGGCCACT TCTCCACCAC CCCGATGCTG 3480
TCCTTGCGCC AGAGGATGAT GCATGCCAGA TTCCGTAACC CTCTCTCCCG ACAGCCTGCC 3540
AGACCCTCTT ACAGACAAGG TTATAATGGC AGACCAAATG TAGAAGGGAA AGTCCTTCCT 3600
GGTAGTAATG GAAAACCGAA TGGACAGAGA ATTATCAATG GCCCTCAAGG AACAAAGTGG 3660
GTTGTβGACC TTGATCGTGG GTTAGTATTG AATGCAGAAG GAAGGTACCT CCAAGATTCA 3720
CATGGAAATC CTCTTCGGAT TAAACTAGGA GGAGATGGTC GAACCATTGT AGATCTGGAA 3780
GGGACCCCCG TGGTGAGTCC TGACGGCCTC CCACTCTTTG GGCAGGGGCG ACATGGCACA 3840
CCTCTGGCCA ATGCCCAAGA TAAGCCAATT TTGAGTCTTG GAGGAAAβCC GCTGGTGGGC 3900
TTβGAGGTCA TCAAAAAAAC CACCCATCCC CCTACCACTA CCATGCAGCC CACCACTACT 3960
ACGACGCCCC TGCCTACCAC TACAACCCCG AGGCCCACCA CTGCCACCAC CATGCAGCCC 4020
ACCACTACTA CGACGCCCCT GCCTACCACT ACACCGAGGC CCACCACTGC CACCACCCGC 4080
CGCACGACCA CCAGGCGTCC AACAACCACA GTCCCAACCA CTACGCGGAC AACCACCACC 4140
ACCACCCCCA AACCCACCAC TCCCATCCCC ACCTGTCCCC CTGGGACCTT GGAACβGCAC 4200
6ACGATGATG GCAACCTGAT AATGAGCTCC AATGGGATCC CAGAGTGCTA CGCTGAAGAA 4260
GATGAGTTCT CAGGCTTGGA GACTGACACT GCAGTACCTA CGGAAGAβGC CTACGTTATA 4320
TATGATGAAG ATTATGAATT TGAGACGTCA AGGCCACCAA CCACCACTGA GCCTTCGACC 4380
ACTGCTACCA CACCGAGGGT GATCCCAGAG GAAGGCGCCA TCAGTTCCTT TCCTGAAGAA 4440
GAATTTGATC TGGCTGGAAG GAAACGATTT GTTGCTCCTT ACGTGACGTA CCTAAATAAA 4500
GACCCATCAG CCCCGTGCTC TCTβACTCAT GCACTGGATC ACTTCCAAGT GGACAGCCTG 4560
GATGAAATCA TCCCCAATGA CCTGAAGAAG AGTGATCTGC CTCCCCAGCA TGCTCCCCGC 4620
AACATCACCG TGCTGGCCGT GGAAGGTTGC CACTCATTTG TCATTGTO3A TTGGGACAAA 4680
GCCACCCCAG CAGATTTGGT CACAGGTTAT TTGβTTTACA GTGCATCCTA TGAA6ATTTC 4740
ATCAGGAACA AGTTTTCCAC TCAAGCTTCA TCAGTAACTC ACTTGCCCAT TGAβAACCTA 4800
AACCCCAACA CGAGGTATTA TTTTAAAGTG CAAGCACAAA ATCCTCATGG CTACGGACCT 4860
ATCAGCCCTT CGGTCTCATT TGTCACCGAA TCAGATAATC CTCTGCTTGT TGTGAGGCCC 4920
CCAGGCGβTG AGCTATCTGG ATCCCATTCG CTTTCAAACA TGATCCCAGC TACACGGACT 4980
GCCATβGACG GCAATATβTG AAGCGCACβT 6GTATCGAAA GTTCGTGGGA GTT6TTCTTT 5040 βTAATTCACT βAGGTATAAA ATCTACCTCA GTGACAACCT GAAAGATACA TTCTACAGCA 5100
TTGGAGACAG CTGGGGAAGA GGTGAAGACC ATTGCCAATT TGTGGATTCA CACCTTGATG 5160
GAAGAACAGG GCCTCAGTCC TATGTAGAAG CCCTCCCTAC TATTCAAGGC TACTATCGCC 5220
AGTATCGTCA GGAGCCTGTC AGGTTTGGGA ACATCGβCTT CGGAACCCCC TACTACTATG 5280
TGGGCTGGTA CGAGTGTGGG GTCTCCATCC CTGGAAAGTG GTAATCACAG GACCGTCATβ 5340
CTGCAAGCTT GCCCTGCCCA GCCCCACCAA CTAAGTCGCA CTAGGGGCTG TGAGCAAAGA 5400
CAGCCAGCAT GCTCAGCCCC GCTGCCCTAG GTGCCAGGAA GGTCACAGAT GGACACTGGC 5460
CATTCTGGTC ATCTCAGTCT GGAACTCAGT CCCACTTCTT GGCCTGGACA ATGAACAGGA 5S20
TTCAGTTTTG CTGTTAACTT TGCTTCTCTA CTTTTTTTTG TTTGTTTGTA ATAGCACATC 5580 CCAGAβACAT CAGAAACCAG CAACTGATTC AGTGTGATTT CCCAGACTTT TTAGGCATGA 5640 AATTCCGACA CTTCAGTATT TCCAGGAATA GCATATGCAC GCTGTTCTTG CTTCATGGAA 5700 TGCTACATGC TTTCTGTTTT TCTCATTTTG GATTTCTCCA AAACTAACTG AATTTAAGCT 5760 TCAGGTCCCT TTGTATGCAG TAGAAAGGAA TTATTAAAAA CACCACCAAA GAAAATAAAT 5820 ATATCCTACT TGAAATTTAC TCTATGGACT TACCCACTGC TAβAATAAAT GTATCAAATC 5880 TTATTTGTAA ATTCTCAATT TTGATATATA TATGTATATA TCCATATACA TATCCACACT 5940 TGTCTGCAAG AATATTGATT AAAATTGCTA AATTTGTACT TGTTCACCAA AAAAAAAAAA 6000 AAAAAAA 6007 0 Seq ID NO: C14 DNA Sequence Nucleic Acid Accession ft: NM_003014 Coding sequence: 238..1278
11 21 31 51 5
GβCGGGTTCG CGCCCCGAAG GCTGAGAGCT GGCβCTCCTC GTGCCCTGTG TGCCAGACGG 60
CGGAGCTCCG CGGCCGGACC CCGCGGCCCC GCTTTGCTGC CGACTGGAGT TTGGGGGAAG 120
AAACTCTCCT GCGCCCCAGA AGATTTCTTC CTCGGCCAAG GGACAGCGAA AGATGAGββT 180
GGCAGGAAGA GAAGGCGCTT TCTGTCTGCC GGGGTCCCAG CGCGAGAGGG CAGTGCCATG 240 0 TTCCTCTCCA TCCTAGTGGC GCTGTGCCTG TGGCTGCACC TGGCGCTGGG CGTGCGCGGC 300
GCGCCCTGCG AGGCGGTGCG CATCCCTATG TGCCGGCACA TGCCCTββAA CATCACGCGG 360
ATGCCCAACC ACCTGCACCA CAGCACGCAG GAGAACGCCA TCCTGGCCAT CGAGCAGTAC 420
GAGGAGCTGG TGβACGTGAA CTGCAGCGCC GTGCTGCGCT TCTTCTTCTG TGCCATGTAC 480
GCGCCCATTT GCACCCTGGA GTTCCTβCAC GACCCTATCA AGCCGTGCAA GTCGGTGTβC 540 5 CAACGCGCβC GCGACGACTG CGAGCCCCTC ATGAAGATGT ACAACCACAG CTGGCCCGAA 600
AGCCTGGCCT GCGACGAGCT GCCTGTCTAT GACCGTGGCG TGTGCATTTC GCCTGAAGCC 660
ATCGTCACββ ACCTCCCGGA GGATGTTAAG TGGATAGACA TCACACCAβA CATGATGGTA 720
CAGGAAAGGC CTCTTGATGT TGACTGTAAA CGCCTAAGCC CCGATCGGTG CAAGTGTAAA 780
AAGGTβAAGC CAACTTTGGC AACGTATCTC AGCAAAAACT ACAGCTATGT TATTCATGCC 840 0 AAAATAAAAG CTGTGCAGAG GAGTGGCTGC AATGAGGTCA CAACGGTGGT GGATGTAAAA 900
GAGATCTTCA AGTCCTCATC ACCCATCCCT CGAACTCAAG TCCCGCTCAT TACAAATTCT 960
TCTTGCCAGT GTCCACACAT CCTGCCCCAT CAAGATGTTC TCATCATGTG TTACGAGTGG 1020
CGTTCAAGGA TGATGCTTCT TGAAAATTGC TTAGTTGAAA AATGGAGAGA TCAGCTTAGT 1080
AAAAGATCCA TACAGTGGGA AGAGAGGCTG CAGβAACAGC GβAGAACAGT TCAGGACAAG 1140 5 AAGAAAACAG CCGGGCGCAC CAGTCGTAGT AATCCCCCCA AACCAAAGGG AAAGCCTCCT 1200
GCTCCCAAAC CAGCCAGTCC CAAGAAGAAC ATTAAAACTA GβAGTGCCCA GAAGAGAACA 1260
AACCCGAAAA GAGTGTGAGC TAACTAGTTT CCAAAGCGGA GACTTCCGAC TTCCTTACAG 1320
GATGAGGCTG GGCATTGCCT GGGACAGCCT ATGTAAGGCC ATGTGCCCCT TGCCCTAACA 1380
ACTCACTGCA GTGCTCTTCA TAGACACATC TTGCAGCATT TTTCTTAAGG CTATGCTTCA 1440 0 GTTTTTCTTT GTAAGCCATC ACAAGCCATA GTGGTAGGTT TGCCCTTTGG TACAGAAβGT 1500
GAGTTAAAGC TGGTGGAAAA GGCTTATTGC ATTGCATTCA GAGTAACCTβ TGTGCATACT 1560
CTAGAAGAGT AGGGAAAATA ATGCTTGTTA CAATTCGACC TAATATGTGC ATTGTAAAAT 1620
AAATGCCATA TTTCAAACAA AACACGTAAT TTTTTTACAG TATGTTTTAT TACCTTTTGA 1680
TATCTGTTGT TGCAATGTTA GTGATGTTTT AAAATGTGAT GAAAATATAA TGTTTTTAAG 1740 5 AAGGAACAGT AGTGGAATGA ATGTTAAAAG ATCTTTATGT GTTTATGGTC TGCAGAAGGA 1800
TTTTTGTGAT GAAAGGGGAT TTTTTGAAAA ATTAGAGAAG TAGCATATGG AAAATTATAA 1860
TGTGTTTTTT TACCAATGAC TTCAGTTTCT GTTTTTAGCT AGAAACTTAA AAACAAAAAT 1920
AATAATAAAG AAAAATAAAT AAAAAGGAGA GGCAGACAAT GTCTGGATTC CTGTTTTTTG 1980
GTTACCTGAT TTCCATGATC ATGATβCTTC TTGTCAACAC CCTCTTAAGC AGCACCAGAA 2040
50 ACAGTGAGTT TCTCTGTACC ATTAGGAGTT AGGTACTAAT TAGTTGGCTA ATGCTCAAGT 2100
ATTTTATACC CACAAGAGAG GTATGTCACT CATCTTACTT CCCAGGACAT CCACCCTGAG 2160
AATAATTTGA CAAGCTTAAA AATGGCCTTC ATGTGAGTGC CAAATTTTGT TTTTCTTCAT 2220
TTAAATATTT TCTTTGCCTA AATACATGTG AGAGGAGTTA AATATAAATβ TACAGAGAGG 2280
AAAGTTGAGT TCCACCTCTG AAATGAGAAT TACTTGACAG TTGGGATACT TTAATCAGAA 2340
55 AAAAAGAACT TATTTGCAGC ATTTTATCAA CAAATTTCAT AATTGTGGAC AATTGGAGGC 2400
ATTTATTTTA AAAAACAATT TTATTGGCCT TTTGCTAACA CAGTAAGCAT GTATTTTATA 2460
AGGCATTCAA TAAATGCACA ACGCCCAAAβ GAAATAAAAT CCTATCTAAT CCTACTCTCC 2520
ACTACACAGA GGTAATCACT ATTAGTATTT TGGCATATTA TTCTCCAGGT GTTTGCTTAT 2580
GCACTTATAA AATGATTTGA ACAAATAAAA CTAGGAACCT GTATACATGT GTTTCATAAC 2640
60 CTGCCTCCTT TGCTTGGCCC TTTATTGAGA TAAGTTTTCC TGTCAAGAAA GCAGAAACCA 2700
TCTCATTTCT AACAGCTGTG TTATATTCCA TAGTATGCAT TACTCAACAA ACTβTTGTGC 2760
TATTGGATAC TTAGGTGGTT TCTTCACTGA CAATACTGAA TAAACATCTC ACCGGAATTC 2820
, Seq ID NO: C15 DNA Sequence
OJ Nucleic Acid Accession # : NM_005940
Coding sequence : 23. .1489
1 11 21 31 41 51 1 1 | 1 | 1 | 1 | 1 |
70 1 AAGCCCAGCA GCCCCGGGGC GGATGβCTCC GGCCGCCTGG CTCCGCAGCβ CGGCCGCGCG 60
CCCCCTCCTβ CCCCCGATGC TGCTGCTGCT GCTCCAGCCG CCGCCGCTGC TGGCCCGGGC 120
TCTGCCGCCβ GACGTCCACC ACCTCCATGC CGAGAGGAGG βGGCCACAβC CCTGGCATGC 180
ACCCCTβCCC AGTAGCCCGG CACCTGCCCC TGCCACGCAG GAAGCCCCCC GGCCTGCCAG 240
CAGCCTCAGG CCTCCCCGCT GTGGCGTGCC CGACCCATCT GATGGGCTGA GTGCCCGCAA 300
75 CCGACAGAAG AGGTTCGTGC TTTCTGGCGG GCGCTGGGAG AAβACGGACC TGACCTACAG 360
GATCCTTCGG TTCCCATGGC AGTTGGTGCA GGAGCAGGTG CGGCAGACβA TGGCAGAGGC 420
CC AAAGGTA TGGAGCGATG TGACGCCACT CACCTTTACT GAG6TGCACG AGGGCCGTGC 480
TβACATCATG ATCGACTTCG CCAGGTACTG GCATGGGGAC GACCTGCCGT TTGATGGGCC 540
TGGGGGCATC CTGGCCCATG CCTTCTTCCC CAAGACTCAC CGAGAAGGGG ATGTCCACTT 600
80 CGACTATβAT GAGACCTGGA CTATCGGGGA TGACCAGGGC ACAGACCTGC TGCAGGTGGC 660
AGCCCATGAA TTTGGCCACG TGCTGGGGCT GCAGCACACA ACAGCAGCCA AGGCCCTGAT 720
GTCCGCCTTC TACACCTTTC GCTACCCACT GAGTCTCAGC CCAGATGACT GCAβGGGCGT 780
TCAACACCTA TATβGCCAGC CCTGGCCCAC TGTCACCTCC AGGACCCCAG CCCTGGGCCC 840
CCAGGCTGGG ATAGACACCA ATGAGATTGC ACCGCTGGAG CCAGACGCCC CGCCAGATGC 900 CTGTGAGGCC TCCTTTGACG CGGTCTCCAC CATCCGAGGC GAGCTCTTTT TCTTCAAAGC 960
GGGCTTTGTG TGGCGCCTCC GTGGGGGCCA GCTGCAGCCC GGCTACCCAG CATTGGCCTC 1020
TCGCCACTGG CAGGGACTGC CCAGCCCTGT GGACGCTGCC TTCGAGGATG CCCAGGGCCA 1080
CATTTGβTTC TTCCAAGGTG CTCAGTACTG GGTGTACGAC GGTGAAAAGC CAGTCCTGGG 1140
CCCCGCACCC CTCACCGAGC TGGGCCTGGT GAGGTTCCCG GTCCATGCTG CCTTGGTCTG 1200
GGGTCCCGAG AAGAACAAGA TCTACTTCTT CCGAGGCAGG GACTACTGGC GTTTCCACCC 1260
CAGCACCCGG CGTGTAGACA GTCCCGTGCC CCGCAGGGCC ACTGACTGGA GAGGGβTGCC 1320
CTCTGAGATC GACGCTGCCT TCCAGβATGC TGATGGCTAT GCCTACTTCC TGCGCGGCCG 1380
CCTCTACTGG AAGTTTGACC CTGTGAAGGT GAAGGCTCTG GAAGβCTTCC CCCGTCTCGT 1440 0 GGGTCCTGAC TTCTTTGGCT GTGCCGAGCC TGCCAACACT TTCCTCTGAC CATGGCTTGG 1500
ATGCCCTCAG GGGTGCTGAC CCCTGCCAGG CCACGAATAT CAGGCTAGAG ACCCATGGCC 1560
ATCTTTGTGG CTGTGGGCAC CAGGCATGGG ACTGAGCCCA TGTCTCCTGC AGβeβGATGβ 1620
GGTGCGGTAC AACCACCATG ACAACTGCCG GGAGGGCCAC GCAGGTCGTG GTCACCTGCC 1680
AGCGACTβTC TCAGACTGGG CAGGGAGGCT TTGGCATGAC TTAAGAGGAA GGGCAGTCTT 1740 5 GGGACCCGCT ATGCAGGTCC TGGCAAACCT CβCTGCCCTG TCTCATCCCT GTCCCTCAGβ 1800
GTAβCACCAT GGCAGGACTG GGGGAACTGG AGTGTCCTTG CTGTATCCCT GTTGTGAGGT 1860
TCCTTCCAGG GGCTGGCACT GAAGCAAGGG TCCTGGGGCC CCATGGCCTT CAGCCCTGGC 1920
TGAGCAACTG GGCTGTAGGG CAGGGCCACT TCCTGAGGTC AGGTCTTGGT AGGTGCCTGC 1980
ATCTGTCTGC CTTCTGGCTG ACAATCCTGG AAATCTGTTC TCCAGAATCC AGGCCAAAAA 2040 0 GTTCACAGTC AAATGGGGAG GGGTATTCTT CATGCAGGAG ACCCCAGGCC CTGGAGGCTG 2100
CAACATACCT CAATCCTGTC CCAGGCCGGA TCCTCCTGAA GCCCTTTTCG CAGCACTGCT 2160
ATCCTCCAAA GCCATTGTAA ATGTGTGTAC AGTGTGTATA AACCTTCTTC TTCTTTTTTT 2220
TTTTTAAACT GAGGATTGTC ATTAAACACA GTTGTTTTCT 2260 5 Seq ID NO: C16 DNA Sequence Nucleic Acid Accession ft: NM_024022 Coding sequence: 202..1563
11 21 31 51 0
ACCGGGCACC GGACGGCTCG GGTACTTTCG TTCTTAATTA GGTCATGCCC GTGTGAGCCA 60
GGAAAGGβCT GTGTTTATGG GAAGCCAGTA ACACTGTGGC CTACTATCTC TTCCGTGGTG 120
CCATCTACAT TTTTGGGACT CGGGAATTAT GAGGTAGAGG TGGAGGCGβA GCCGGATGTC 180
AGAGGTCCTG AAATAGTCAC CATGGGGGAA AATGATCCGC GTGCTGTTGA AGCCCCCTTC 240 5 TCATTCCGAT CGCTTTTTGG CCTTGATGAT TTGAAAATAA GTCCTGTTGC ACCAGATGCA 300
GATGCTGTTG CTGCACAGAT CCTGTCACTG CTGCCATTGA AGTTTTTTCC AATCATCGTC 360
ATTGGGATCA TTGCATTGAT ATTAGCACTG GCCATTGGTC TGGGCATCCA CTTCGACTGC 420
TCAGβGAAGT ACAGATGTCG CTCATCCTTT AAGTGTATCG AGCTGATAGC TCβATGTGAC 480
GGAGTCTCGG ATTGCAAAGA CGGGGAGGAC GAGTACCGCT GTGTCCGGGT GGGTGGTCAG 540 0 AATGCCGTGC TCCAGGTGTT CACAGCTGCT TCGTGGAAGA CCATGTGCTC CGATGACTGβ 600
AAGGGTCACT ACGCAAATGT TGCCTGTGCC CAACTGGGTT TCCCAAGCTA TGTGAGTTCA 660
GATAACCTCA GAGTGAGCTC GCTGGAGGGG CAGTTCCGGG AGGAGTTTGT GTCCATCGAT 720
CACCTCTTGC CAGATGACAA GGTGACTGCA TTACACCACT CAGTATATGT GAGGGAGGGA 780
TGTGCCTCTG GCCACGTGGT TACCTTGCAG TGCACAGCCT GTGGTCATAG AAGGGGCTAC 840 5 AGCTCACGCA TCGTGGβTGG AAACATβTCC TTGCTCTCGC AGTGGCCCTG GCAGGCCAGC 900
CTTCAGTTCC AGGGCTACCA CCTGTGCGGG GGCTCTGTCA TCACGCCCCT GTGGATCATC 960
ACTGCTGCAC ACTGTGTTTA TGACTTGTAC CTCCCCAAGT CATGβACCAT CCAGGTGGGT 1020
CTAGTTTCCC TGTTGGACAA TCCAGCCCCA TCCCACTTGG TGGAGAAGAT TGTCTACCAC 1080
AGCAAGTACA AGCCAAAGAG GCTGGGCAAT GACATCGCCC TTATGAAGCT GGCCGβGCCA 1140 0 CTCACGTTCA ATGAAATGAT CCAGCCTGTG TGCCTGCCCA ACTCTGAAGA GAACTTCCCC 1200
GATGGAAAAG TGTGCTGGAC GTCAGGATGG GGGGCCACAG AGGATGGAGG TGACGCCTCC 1260
CCTGTCCTGA ACCACGCGGC CGTCCCTTTβ ATTTCCAACA AGATCTGCAA CCACAGGGAC 1320
GTGTACGGTG GCATCATCTC CCCCTCCATG CTCTGCGCGG GCTACCTGAC GGGTGGCGTG 1380
GACAGCTGCC AGGGGGACAG CGGGGGGCCC CTGGTGTGTC AAGAGAGGAG GCTGTGGAAG 1440 5 TTAGTGGGAG CGACCAGCTT TGGCATCGGC TGCGCAGAGG TGAACAAGCC TGGGGTGTAC 1500
ACCCGTGTCA CCTCCTTCCT GGACTGβATC CACGAGCAGA TGGAGA6A6A CCTAAAAACC 1560
TGAAGAGβAA GGGGACAAGT AGCCACCTGA GTTCCTGAGG TGATGAAGAC AGCCCGATCC 1620
TCCCCTGGAC TCCCGTGTAG GAACCTGCAC ACGAβCAGAC ACCCTTGGAG CTCTGAGTTC 1680
CGGCACCAGT AGCAGGCCCG AAAGAGGCAC CCTTCCATCT GATTCCAGCA CAACCTTCAA 1740 0 GCTGCTTTTT GTTTTTTGTT TTTTTGAGGT GGAGTCTCGC TCTGTTGCCC AGGCTGGAGT 1800
GCAGTGGCGA AATCCCTGCT CACTGCAGCC TCCGCTTCCC TGGTTCAAGC GATTCTCTTG 1860
CCTCAGCTTC CCCAGTAGCT GGGACCACAG GTGCCCGCCA CCACACCCAA CTAATTTTTβ 1920
TATTTTTAGT AGAGACAGGG TTTCACCATG TTGGCCAGGC TGCTCTCAAA CCCCTGACCT 1980
CAAATGATGT GCCTGCTTCA GCCTCCCACA GTGCTGGGAT TACAGGCATG GGCCACCACG 2040 5 CCTAGCCTCA CGCTCCTTTC TGATCTTCAC TAAGAACAAA AGAAGCAGCA ACTTGCAAGG 2100
GCGGCCTTTC CCACTGGTCC ATCTGGTTTT CTCTCCAGGG GTCTTGCAAA ATTCCTGACG 2160
AGATAAGCAG TTATGTGACC TCACGTGCAA AGCCACCAAC AGCCACTCAG AAAAGACGCA 2220
CCAGCCCAGA AGTGCAGAAC TGCAGTCACT GCACGTTTTC ATCTCTAGGG ACCAGAACCA 2280
AACCCACCCT TTCTACTTCC AAGACTTATT TTCACATGTG GGGAGGTTAA TCTAGGAATG 2340 0 ACTCβTTTAA GGCCTATTTT CATGATTTCT TTGTAGCATT TGGTGCTTGA CGTATTATTβ 2400
TCCTTTβATT CCAAATAATA TGTTTCCTTC CCTCAAAAAA AAAAAAAAAA AAAAAAAAAA 2460
AAAAA 2465
_ Seq ID NO: C17 DNA Sequence I D Nucleic Acid Accession #: NM_003220
Coding sequence: 63..1376
11 21 31 41 51
I 0 I I I I
GAATTCCGGC TCTCTGGGTG AGAGACCGAG AGGGGCATAT CCGTTCACGC CGATCCATGA 60 AAATGCTTTG GAAATTGACG GATAATATCA AGTACGAGGA CTGCβAGβAC CGTCACGACβ 120 GCACCAGCAA CGGGACGGCA CGGTTGCCCC AβCTGGGCAC TGTAGGTCAA TCTCCCTACA 180 CGAGCGCCCC GCCGCTGTCC CACACCCCCA ATGCCGACTT CCAGCCCCCA TACTTCCCCC 240 CACCCTACCA GCCTATCTAC CCCCAGTCGC AAGATCCTTA CTCCCACGTC AACGACCCCT 300 ACAGCCTGAA CCCCCTβCAC GCCCAGCCGC AGCCGCAGCA CCCAGGCTGG CCCGGCCAβA 360
GGCAGAGCCA GGAGTCTCGβ CTCCTGCACA CGCACCGGGG GCTGCCTCAC CAGCTGTCGG 420
GCCTGGATCC TCGCAGGGAC TACAGGCGGC ACGAGGACCT CCTGCACGGC CCACACGCGC 480
TCAGCTCAGG ACTCGGAGAC CTCTCGATCC ACTCCTTACC TCACGCCATC GAGGAGGTCC 540
CGCATGTAGA AGACCCGGGT ATTAACATCC CAGATCAAAC TGTAATTAAG AAAGGCCCCG 600
TCTCCCTGTC CAAGTCCAAC AGCAATGCCG TCTCCGCCAT CCCTATTAAC AAGGACAACC 660
TCTTCGGCGG CGTβGTGAAC CCCAACGAAG TCTTCTGTTC AGTTCCGGGT CGCCTCTCGC 720
TCCTCAGCTC CACCTCGAAG TACAAGGTCA CGGTGGCGGA AGTGCAGCGG CGGCTCTCAC 780
CACCCGAGTG TCTCAACGCG TCGCTGCTGβ GCβGAGTGCT CCGGAGGGCG AAGTCTAAAA 840
ATG6AGGAAG ATCTTTAAGA GAAAAACTGG ACAAAATAGG ATTAAATCTG CCTGCAGGGA 900
GACβTAAAGC TGCCAACCTT ACCCTGCTCA CATCACTAGT AGAGGGAGAA GCTGTCCACC 960
TAGCCAGGGA CTTTGGGTAC GTGTGCGAAA CCGAATTTCC TGCCAAAGCA GTAGCTGAAT 1020
TTCTCAACCG ACAACATTCC GATCCCAATG AGCAAGTGAC AAGAAAAAAC ATGCTCCTGG 1080
CTACAAAACA GATATGCAAA GAGTTCACCG ACCTGCTGGC TCAGGACCGA TCTCCCCTGG 1140
GGAACTCACG GCCCAACCCC ATCCTGGAGC CCβGCATCCA GAGCTGCTTG ACCCACTTCA 1200
ACCTCATCTC CCACGGCTTC GGCAGCCCCG CGGTGTGTGC CGCGGTCACG GCCCTGCAGA 1260
ACTATCTCAC CGAGGCCCTC AAGβCCATGG ACAAAATGTA CCTCAGCAAC AACCCCAACA 1320
GCCACACGGA CAACAACGCC AAAAGCAβTG ACAAAGAGGA GAAGCACAGA AAGTGAGGCT 1380
CTCCTCCCGC CCCGCCCCTC CCACGCCTCA CCAGCCCCCC GCGCGCCCAC CCTCCGGCGG 1440
GTGACAGCTC CGGGATCAGC AACCCTTCCT GCTGCTGCTA CTGCTGCTGC TGCTGCCGCC 1500
GCCGCCGCCG CCCCTGCCCT TGGGTCCCCC CGAGTCTCCG GGACTGCCCT CTCGACTGTC 1560
AGTGGGGCAG CCTCTCCβAC TCTGCACCCG CCTCGACCTC CCCACCCGCT CCCACACCCC 1620
TGTGCCCCCG GAATTC 1636
Seq ID NO: C18 DNA Sequence Nucleic Acid Accession #: NM_002988 Coding sequence: 71..340
11 21 31 41 51
I I I I
CCGGCACGAG AGGAGTTGTG AGTTTCCAAG CCCCAβCTCA C 1TCTGACCAC TTCTCTGCCT 60 GCCCAGCATC ATGAAGGGCC TTβCAGCTGC CCTCCTTβTC CTCGTCTGCA CCATGGCCCT 120 CTGCTCCTGT GCACAAGTTβ GTACCAACAA AGAGCTCTGC TGCCTCGTCT ATACCTCCTG 180 GCAGATTCCA CAAAAGTTCA TAGTTβACTA TTCTGAAACC AGCCCCCAGT GCCCCAAGCC 240 AGGTGTCATC CTCCTAACCA AGAGAGGCCβ GCAGATCTGT GCTGACCCCA ATAAGAAGTG 300 GGTCCAGAAA TACATCAGCβ ACCTGAAβCT GAATβCCTGA GGGGCCTGGA AGCTGCGAGG 360 GCCCAGTGAA CTTGGTGGGC CCAG6AGGGA ACAGGAβCCT GAGCCAGGGC AATGGCCCTG 420 CCACCCTGGA GGCCACCTCT TCTAAGAβTC CCATCTGCTA TGCCCAGCCA CATTAACTAA 480 CTTTAATCTT AGTTTATGCA TCATATTTCA TTTTGAAATT GATTTCTATT GTTGAGCTGC 540 ATTATGAAAT TAGTATTTTC TCTβACATCT CATGACATTG TCTTTATCAT CCTTTCCCCT 600 TTCCCTTCAA CTCTTCGTAC ATTCAATCCA TGGATCAATC AGTGTGATTA GCTTTCTCAG 660 CAGACATTGT GCCATATGTA TCAAATβACA AATCTTTATT GAATGGTTTT GCTCAGCACC 720 ACCTTTTAAT ATATTGGCAβ TACTTATTAT ATAAAAGGTA AACCAGCATT CTCACTGT6A 780 AAAAAAAAAA AAAAAAAAAA AAA 803
Seq ID NO: C19 DNA Sequence Nucleic Acid Accession ft: NM_004063 Coding sequence: 121..2619
1 11 21 31 41 51
1 1 | 1 | 1 | 1 | 1 | 1 AGGGAGTGTT CCCGGGGGAG ATACTCCAGT CGTAβCAAGA GTCTCGACCA CTGAATGGAA 60
GAAAAGGACT TTTAACCACC ATTTTGTGAC TTACAGAAAG GAATTTGAAT AAAGAAAACT 120
ATGATACTTC AGGCCCATCT TCACTCCCTG TGTCTTCTTA TGCTTTATTT GGCAACTGGA 180
TATGGCCAAG AGGGGAAGTT TAGTGGACCC CTGAAACCCA TGACATTTTC TATTTATGAA 240
GGCCAAGAAC CGAGTCAAAT TATATTCCAG TTTAAGGCCA ATCCTCCTβC TGTGACTTTT 300
GAACTAACTG GGGAGACAGA CAACATATTT GTGATAGAAC GGGAGGGACT TCTGTATTAC 360
AACAGAGCCT TGGACAGGGA AACAAGATCT ACTCACAATC TCCAGGTTGC AGCCCTGGAC 420
GCTAATGGAA TTATAGTGGA GGGTCCACTC CCTATCACCA TAGAAGTβAA GGACATCAAC 480
GACAATCCAC CCACGTTTCT CCAGTCAAAG TACGAAGGCT CAGTAAGGCA GAACTCTCGC 540
CCAGGAAAGC CCTTCTTGTA TGTCAATGCC ACAGACCTββ ATGATCCGGC CACTCCCAAT 600
GGCCAGCTTT ATTACCAGAT TGTCATCCAG CTTCCCATGA TCAACAATGT CATGTACTTT 660
CAGATCAACA ACAAAACGGG AGCCATCTCT CTTACCCGAG AGGGATCTCA GGAATTGAAT 720
CCTGCTAAGA ATCCTTCCTA TAATCTGGTG ATCTCAGTGA AβGACATGGβ AGGCCAGAGT 780
GAGAATTCCT TCAGTβATAC CACATCTGTG GATATCATAG TGACAGAGAA TATTTGGAAA 840
GCACCAAAAC CTGTββAGAT GGTββAAAAC TCAACTGATC CTCACCCCAT CAAAATCACT 900
CAGGTGCGGT GGAATGATCC CββTGCACAA TATTCCTTAG TTGACAAAGA GAAβCTGCCA 960
AGATTCCCAT TTTCAATTGA CCAGGAAGGA GATATTTACG TGACTCAGCC CTTGGACCGA 1020
GAAGAAAAGG ATGCATATGT TTTTTATGCA GTTGCAAAGG ATGACTACGG AAAACCAGTT 1080
TCATATCCGC TGGAAATTCA TGTAAAAGTT AAAGATATTA ATGATAATCC ACCTACATGT 1140
CCGTCACCAG TAACCGTATT TGAGGTCCAG GAGAATGAAC GACTGGGTAA CAGTATCGGG 1200
ACCCTTACTG CACATGACAβ GGATGAAGAA AATACT6CCA ACAGTTTTCT AAACTACAGG 1260
ATTGTGGAGC AAACTCCCAA ACTTCCCATG GATGβACTCT TCCTAATCCA AACCTATGCT 1320
GGAATGTTAC AGTTAGCTAA ACAGTCCTTG AAGAAGCAAG ATACTCCTCA βTACAACTTA 1380
ACGATAGAGG TGTCTGACAA AGATTTCAAG ACCCTTTGTT TTGTGCAAAT CAACGTTATT 1440
GATATCAATG ATCAGATCCC CATCTTTGAA AAATCAGATT ATGGAAACCT GACTCTTGCT 1500
GAAGACACAA ACATTGGGTC CACCATCTTA ACCATCCAGG CCACTGATGC TGATGAGCCA 1560
TTTACTGGGA GTTCTAAAAT TCTGTATCAT ATCATAAAGG GAGACAGTGA GGGACGCCTG 1620
GGGGTTGACA CAGATCCCCA TACCAACACC GGATATGTCA TAATTAAAAA GCCTCTTGAT 1680
TTTGAAACAG CAGCTGTTTC CAACATTGTG TTGAAAGCAG AAAATCCTGA GCCTCTAGTG 1740
TTTGGTGTGA AGTACAATGC AAGTTCTTTT GCCAAGTTCA CGCTTATTGT GACAGATGTG 1800
AATGAAGCAC CTCAATTTTC CCAACACGTA TTCCAAGCGA AAGTCAGTβA CβATβTAGCT 1860
ATAGGCACTA AAGTGβGCAA TGTGACTGCC AAGGATCCAG AAGGTCTGGA CATAAGCTAT 1920
TCACTGAGGG GAGACACAAG AGGTTGGCTT AAAATTGACC ACGTGACTGG TGAGATCTTT 1980 AGTβTGGCTC CATTGGACAG AGAAGCCGGA AGTCCATATC GGGTACAAGT ββTGGCCACA 2040
GAAGTAGGGβ GGTCTTCCTT GAGCTCTGTG TCAGAGTTCC ACCTGATCCT TATGGATGTG 2100
AATGACAACC CTCCCAGGCT AGCCAAGβAC TACACββGCT TGTTCTTCTG CCATCCCCTC 2160
AGTGCACCTG GAAGTCTCAT TTTCβAGGCT ACTGATGATβ ATCAGCACTT ATTTCGGGGT 2220
CCCCATTTTA CATTTTCCCT CGGCAGTGGA AGCTTACAAA ACGACTGGGA AGTTTCCAAA 2280
ATCAATGGTA CTCATGCCCG ACTGTCTACC AGGCACACAG AGTTTGAGGA GAGGGAβTAT 2340
GTCGTCTTGA TCCGCATCAA TGATGββββT CGGCCACCCT TGGAAGGCAT TβTTTCTTTA 2400
CCAGTTACAT TCTGCAGTTG TβTGGAAGGA AGTTGTTTCC GβCCAGCAGG TCACCAGACT 2460
CGGATACCCA CTGTGGGCAT GGCAGTTGGT ATACTGCTGA CCACCCTTCT GGTGATTGβT 2520
ATAATTTTAβ CAGTTGTGTT TATCCGCATA AAGAAGβATA AAGGCAAAGA TAATGTTGAA 2580
AGTGCTCAAG CATCTGAAGT CAAACCTCTG AGAAGCTGAA TTTGAAAAGG AATGTTTGAA 2640
TTTATATAGC AAGTGCTATT TCAGCAACAA CCATCTCATC CTATTACTTT TCATCTAACG 2700
TGCATTATAA TTTTTTAAAC AGATATTCCC TCTTGTCCTT TAATATTTGC TAAATATTTC 2760
TTTTTTGAGG TGGAGTCTTG CTCTGTCGCC CAGGCTβGAG TACAGTGGTβ TGATCCCAGC 2820
TCACTGCAAC CTCCGCCTCC TGGGTTCACA TGATTCTCCT GCCTCAGCTT CCTAAβTAβC 2880
TGGGTTTACA GGCACCCACC ACCATGCCCA βCTAATTTTT GTATTTTTAA TAGAGACGGβ 2940
GTTTCGCCAT TTGGCCAGGC TGGTCTTGAA CTCCTGACGT CAAGTGATCT GCCTGCCTTG 3000
GTCTCCCAAT ACAGGCATGA ACCACTGCAC CCACCTACTT AGATATTTCA TGTGCTATAG 3060
ACATTAGAGA GATTTTTCAT TTTTCCATGA CATTTTTCCT CTCTGCAAAT GGCTTAGCTA 3120
CTTGTGTTTT TCCCTTTTGβ GGCAAGACAG ACTCATTAAA TATTCTGTAC ATTTTTTCTT 3180
TATCAAGGAG ATATATCAβT GTTGTCTCAT AGAACTGCCT GGATTCCATT TATGTTTTTT 3240
CTGATTCCAT CCTβTGTCCC CTTCATCCTT GACTCCTTTG GTATTTCACT GAATTTCAAA 3300
CATTTGTCAG AGAAGAAAAA CGTβAGGACT CAGGAAAAAT AAATAAATAA AAGAACAGCC 3360
TTTTCCCTTA GTATTAACAG AAATGTTTCT GTGTCATTAA CCATCTTTAA TCAATGTGAC 3420
ATGTTGCTCT TTGGCTGAAA TTCTTCAACT TGGAAATGAC ACAGACCCAC AGAAGGTGTT 3480
CAAACACAAC CTACTCTβCA AACCTTGGTA AAGGAACCAG TCAGCTGGCC AGATTTCCTC 3540
ACTACCTGCC ATCCATACAT GCTGCGCATG TTTTCTTCAT TCGTATGTTA GTAAAGTTTT 3600
GGTTATTATA TATTTAACAT GTGGAAGAAA ACAAGACATG AAAAGAGTGβ TGACAAATCA 3660
AGAATAAACA CTGGTTGTAG TCAGTTTTGT TTGTTAA 3697
Seq ID NO: C20 DNA Sequence Nucleic Acid Accession #: NM_004443 Coding sequence: 28..3024
11 21 31 41 51
GGCTCGGCTC CTAGAGCTGC CIACGGCCATG GCCAGAGCCC GCCCGCCβCC GCCGCCGTCG 60 CCGCCeCCGG GGCTTCTGCC GCTGCTCGCT CCβCTGCTGC TGCTGCCGCT GCTGCTGCTG 120 CCCGCCGGCT GCCββGCGCT GGAAGAGACC CTCAT6GACA CAAAATGGGT AACATCTβAβ 180 TTGGCGTGGA CATCTCATCC AGAAAGTGGG TG6GAAGAGG TGAGTGGCTA CGATGAGGCC 240 ATGAATGCCA TCCGCACATA CCAGGTGTGT AATGTGCGCG AGTCAAGCCA GAACAACTGβ 300 CTTCGCACGG GGTTCATCTG GCGGCGGGAT GTGCAGCGGG TCTACGTGGA GCTCAAGTTC 360 ACTGTGCGTG ACTGCAACAβ CATCCCCAAC ATCCCCGGCT CCTGCAAG6A GACCTTCAAC 420 CTCTTCTACT ACGAGGCTGA CAGCGATGTG βCCTCAGCCT CCTCCCCCTT CTGGATGGAG 480 AACCCCTACG TGAAAGTGGA CACCATTGCA CCCGATGAGA βCTTCTCGCG GCTGGATGCC 540 GGCCGTGTCA ACACCAAGGT GCGCAGCTTT GGGCCACTTT CCAAGGCTGG CTTCTACCTG 600 GCCTTCCAGG ACCAGGGCGC CTGCATGTCG CTCATCTCCG TGCGCGCCTT CTACAAGAAG 660 TGTGCATCCA CCACCGCAGG CTTCGCACTC TTCCCCGAGA CCCTCACTGG GGCGβAβCCC 720 ACCTCGCTGG TCATTGCTCC TGGCACCTGC ATCCCTAACG CCGTGGAGGT GTCGβTβCCA 780 CTCAAGCTCT ACTGCAACGβ CGATGGGGAG TGGATGGTGC CTGTGGGTGC CTGCACCTGT 840 GCCACCGGCC ATβAβCCAGC TGCCAAGGAG TCCCACTGCC GCCCCTGTCC CCCTGGGAGC 900 TACAAGGCGA AGCAGGGAGA GGβGCCCTGC CTCCCATGTC CCCCCAACAG CCGTACCACC 960 TCCCCAGCCG CCAGCATCTG CACCTGCCAC AATAACTTCT ACCGTGCAβA CTCGGACTCT 1020 GCGGACAGTG CCTGTACCAC CGTGCCATCT CCACCCCGAG GTGTGATCTC CAATGTGAAT 1080 GAAACCTCAC TGATCCTCGA GTGGAGTGAβ CCCCGGGACC TGGGTGGCCG GGATGACCTC 1140 CTGTACAATG TCATCTGCAA GAAβTGCCAT GGGGCTGGAG GGβCCTCAβC CTGCTCACGC 1200 TGTGATGACA ACGTGGAGTT TGTGCCTCGG CAGCTGGGCC TGACGGAβCβ CCGGGTCCAC 1260 ATCAGCCATC TGCTGGCCCA CACGCGCTAC ACCTTTGAGG TGCAGGCGGT CAACGGTGTC 1320 TCGGGCAAGA GCCCTCTGCC GCCTCGTTAT GCCGCCGTGA ATATCACCAC AAACCAGβCT 1380 GCCCC6TCTG AAGTGCCCAC ACTACGCCTG CACAGCAGCT CAGGCAGCAG CCTCACCCTA 1440 TCCTGGGCAC CCCCAGAGCG GCCCAACGGA GTCATCCTGG ACTACGAGAT GAAGTACTTT 1500 GAGAAGAGCG AGGGCATCGC CTCCACAGTG ACCAGCCAGA TGAACTCCGT GCAGCTGGAC 1560 GGGCTTCGGC CTGACGCCCG CTATGTβGTC CAGGTCCGTG CCCGCACAGT AGCTGGCTAT 1620 GGGCAGTACA GCCGCCCTGC CCAGTTTGAG ACCACAAGTG AGAGAGGCTC TGGGGCCCAG 1680 CAGCTCCAGG AGCAGCTTCC CCTCATCGTG GGCTCCGCTA CAGCTGGGCT TGTCTTCGTG 1740 GTGGCTGTCG TGGTCATCGC TATCGTCTGC CTCAGGAAGC AβCGACACGG CTCTGATTCG 1800 GAGTACACGG AGAAGCTGCA GCAGTACATT GCTCCTGGAA TGAAGGTTTA TATTGACCCT 1860 TTTACCTACG AGGACCCTAA TGAGGCTGTT CGGGAGTTTG CCAAGGAGAT CGACGTGTCC 1920 TGCGTCAAGA TCGAGGAGGT GATCGGAGCT GGGGAATTTG GGGAAGTGTG CCGTGGTCGA 1980 CTGAAACAGC CTGGCCGCCG AGAGGTGTTT GTGGCCATCA AGACGCT6AA GGTGGGCTAC 2040 ACCGAGAGGC AGCGGCGGGA CTTCCTAAGC βAGGCCTCCA TCATGβGTCA GTTTGATCAC 2100 CCCAATATAA TCCGGCTCGA GβGCGTGGTC ACCAAAAGTC GGCCAGTTAT GATCCTCACT 2160 GAGTTCATGG AAAACTGCGC CCTGGACTCC TTCCTCCGGC TCAACGATGG GCAGTTCACβ 2220 GTCATCCAGC TGGTGGGCAT GTTGCGGGGC ATTGCTGCCG GCATGAAGTA CCTGTCCGAG 2280 ATGAACTATG TGCACCGCGA CCTGGCTGCT CGCAACATCC TTGTCAACAC CAACCTGGTC 2340 TGCAAAGTCT CAGACTTTGG CCTCTCCCGC ! TTCCTGGAGG ATGACCCCTC CGATCCTACC 2400 TACACCAGTT CCCTGGGCGG GAAGATCCCC ! ATCCβCTGβA CTGCCCCAGA GGCCATAGCC 2460 TATCGGAAGT TCACTTCTGC TAGTGATGTC I TGGAGCTACG GAATTGTCAT GTGβGAGGTC 2520 ATGAGCTATG GAGAGCGACC CTACTβGGAC 1 ATGAβCAACC AGGATGTCAT CAATGCCGTG 2580 GAGCAGGATT ACCGβCTβCC ACCACCCATG 1 GACTGTCCCA CAβCACTβCA CCAGCTCATG 2640 CTGGACTGCT GGGTGCGβGA CCGGAACCTC ! AββCCCAAAT TCTCCCAGAT TGTCAATACC 2700 CTGGACAAGC TCATCCGCAA TGCTGCCAGC I CTCAAGGTCA TTGCCAβCGC TCAGTCTGGC 2760 ATGTCACAGC CCCTCCTGGA CCβCACβGTC ! CCAGATTACA CAACCTTCAC GACAGTTGGT 2820 GATTGGCTβG ATGCCATCAA GATGGGGCGG TACAAGGAGA GCTTCGTCAG TGCGGGGTTT 2880
GCATCTTTTG ACCTGGTGGC CCAβATβACG GCAGAAGACC TGCTCCGTAT TGGGGTCACC 2940
CTGGCCGGCC ACCAGAAGAA GATCCTGAGC AGTATCCAGG ACATGCGGCT GCAGATGAAC 3000
CAGACGCTGC CTGTGCAGGT CTGACACCGG CTCCCACGGG GACCCTGAGG ACCCTGCAGG 3060
GATGCCAAGC AGCCGGCTGG ACTTTCGGAC TCTTGGACTT TTGGATGCCT GGCCTTAGGC 3120
TGTGGCCCAβ AAGCTGGAAG TTTGGGAAAG GCCCAAGCTG GGACTTCTCC AβGCCTGTGT 3180
TCCCTCCCCA GGAAGTGCGC CCCAAACCTC TTCATATTGA AGATGGATTA GGAGAGGGGG 3240
TGATGACCCC TCCCCAAGCC CCTCAGGGCC CAGACCTTCC TGCTCTCCAG CAGGGGATCC 3300
CCACAACCTC ACACTTGTCT GTTCTTCAGT GCTGGAGβTC CTGGCAGGGT CAGGCTGβGG 3360
TAAGCCGGGG TTCCACAGGG CCCA6CCCTG GCAGGGGTCT GGCCCCCCAβ GTAGGCGGAG 3420
AGCAGTCCCT CCCTCAGGAA CTGGAGGAGG GGACTCCAGβ AATGGββAAA TGTGACACCA 3480
CCATCCTGAA GCCAGCTTGC ACCTCCAGTT TGCACAGGβA TTTGTCCTGG GGGCTGAGGG 3540
CCCTβTCCCC ACCCCCGCCC TTGGT6CTGT CATAAAAGβG CAGGCAGGGG CAGGCTGAGG 3600
AGTT6CCCTT TGCCCCCCAG AGACTβACTC TCAGAGCCAG AGATGGβATG TGTGAGTβTG 3660
TβTGTGTGTG TGTGCGCGCG CβCβCβCCTG TGTGTGTGCA CGCACTGGCC TGCACAGAGA 3720
GCATGβGTβA GCGTGTAAAA GCTTGGCCCT GTGCCCTACA ATGβGGCCAG CTGGβCCCAC 3780
AGCAGAATAA AGGCAATAAG ATGAA 3805 Seq ID NO: C21 DNA Sequence
Nucleic Acid Accession #: NM_001804 Coding sequence: 82..879
11 21 31
AGGTGAGCGG TTGCTCGTCG TCGGGGCGβC CGGCAGCGβC GGCTCCAGGβ CCCAGCATGC 60
GCGGGGGACC CCGCGGCCAC CATGTATGTG GGCTATGTGC TGGACAAGGA TTCGCCCGTG 120
TACCCCGGCC CAGCCAGGCC AGCCAGCCTC GGCCTGGGCC CGGCAAACTA CGGCCCCCCG 180
GCCCCGCCCC CGGCGCCCCC GCAGTACCCC GACTTCTCCA GCTACTCTCA CGTGGAGCCG 240
GCCCCCGCGC CCCCGACGGC CTGGGGGGCG CCCTTCCCTG CGCCCAAGGA CGACTGGGCC 300
GCCGCCTACG GCCCGGGCCC CGCGGCCCCT GCCGCCAGCC CAGCTTCGCT GGCATTCGGG 360
CCCCCTCCAG ACTTTAGCCC GGTGCCGGCG CCCCCTGβGC CCGGCCCGGG CCTCCTGGCC 420
CAGCCCCTCG GGGGCCCGGG CACACCGTCC TCGCCCGGAG CGCAGAGGCC GACGCCCTAC 480
GAGTGβATGC GGCGCAGCGT GGCβGCCGGA GGCGGCGβTG GCAGCβGTAA GACTCGGACC 540
AAGGACAAGT ACCGCGTGGT CTACACCGAC CACCAACGCC TGGAGCTGGA GAAGGAGTTT 600
CATTACAGCC GTTACATCAC AATCCGGCGG AAATCACAβC TGGCTGCCAA TCTGβGGCTC 660
ACTGAACGGC AGGTGAAGAT CTGGTTCCAA AACCGGCGβG CAAAGβAGCG CAAAGTGAAC 720
AAGAAGAAAC AGCAβCAGCA ACAGCCCCCA CAGCCGC∞A TGGCCCACGA CATCACGGCC 780
ACCCCAGCCG GGCCATCCCT GβGGGGCCTG TGTCCCAGCA ACACCAGCCT CCTGGCCACC 840
TCCTCTCCAA TGCCTβTGAA AGAGGAGTTT CTGCCATAGC CCCATGCCCA GCCTGTGCGC 900
CGGGββACCT GGGβACTCGG GTGCTGGGAG TGTGGCTCCT GTGGGCCCAG GAβGTCTGGT 960
CCGAGTCTCA GCCCTGACCT TCTGGGACAT GGTGGACAGT CACCTATCCA CCCTCTGCAT 1020
CCCCTTGGCC CATTGTGTGC AGTAAGCCTG TTGGATAAAG ACCTTCCAGC TCCTGTGTTC 1080
TAGACCTCTG GGGGATAAGG GAGTCCAGGG TGGATGATCT CAATCTCCCG TGββCATCTC 1140
AAGCCCCAAA TGGTTGGGGG AGGGGCCTAG ACAAGGCTCC AGGCCCCACC TCCTCCTCCA 1200
TACGTTCAGA GGTGCAGCTG GAGGCCTGTG TGGGGACCAC ACTGATCCTG GAGAAAAGGG 1260
ATGGAGCTGA AAAAGATGGA ATGCTTGCAG AGCATGACCT GAGGAGGGAG GAACGTGGTC 1320
AACTCACACC GCCTCTTCT GCAGCCTCAC CTCTACCTGC CCCCATCATA AGGGCACTGA 1380
GCCCTTCCCA GGCTGGATAC TAAGCACAAA GCCCATAGCA CTGGGCTCTG ATGGCTGCTC 1440
CACTGGGTTA CAβAATCACA GCCCTCATGA TCATTCTCAG TGAβGGCTCT GGATTGAGAG 1500
GGAGGCCCTG GGAGβAGAGA AGGGGGCAGA GTCTTCCCTA CCAGGTTTCT ACACCCCCGC 1560
CAGGCTGCCC ATCAGGGCCC AGGGAGCCCC CAGAGGACTT TATTCGGACC AAGCAGAGCT 1620
CACAGCTGGA CAGGTGTTGT ATATAGAGTG GAATCTCTTG GATGCAGCTT CAAGAATAAA 1680
TTTTTCTTCT CTTTTCAAA 1699
Seq ID NO: C22 DNA Sequence Nucleic Acid Accession #: NM_ )21978 Coding sequence: 36..2603
1 11 21 31 41 51 1 1 | 1 J 1 | 1 | 1 | 1
GACGCCTGTG AGACCCGCGA GCGGCCTCGG GGACCATGGG GAGCGATCGG GCCCGCAAGG 60
GCGGAGGGGG CCCGAAGGAC TTCGGCGCGβ GACTCAAGTA CAACTCCCGG CACGAGAAAG 120
TGAATGGCTT GGAGGAAGGC GTβGAGTTCC TGCCAGTCAA CAACGTCAAG AAGGTGGAAA 180
AGCATGGCCC GGGGCGCTGG GTGGTGCTGG CAGCCGTGCT GATCGGCCTC CTCTTGGTCT 240
TGCTGGGGAT CGGCTTCCTG GTGTβGCATT TGCAGTACCG GGACGTGCGT GTCCAGAAGG 300
TCTTCAATGG CTACATGAGG ATCACAAATG AGAATTTTGT GGATGCCTAC GAGAACTCCA 360
ACTCCACTGA GTTTGTAAGC CTGGCCAGCA AGGTGAAGGA CGCGCTGAAG CTGCTGTACA 420
GCGGAGTCCC ATTCCTGGGC CCCTACCACA AGGAGTCGGC TGTGACGGCC TTCAGCGAGG 480
GCAGCGTCAT CβCCTACTAC TβGTCTGAGT TCAGCATCCC GCACCACCTG βTGGAGGAGG 540
CCGAGCGCGT CATGGCCGAG GAGCGCGTAG TCATGCTGCC CCCGCGGGCG CGCTCCCTGA 600
AGTCCTTTGT GGTCACCTCA GTGGTβGCTT TCCCCACGGA CTCCAAAACA GTACAGAGGA 660
CCCAGGACAA CAGCTGCAGC TTTGGCCTGC ACGCCCGCGG TCTGGAGCTG ATGCGCTTCA 720
CCACGCCCGG CTTCCCTGAC AGCCCCTACC CCGCTCATGC CCGCTGCCAG TGGGCCCTGC 780
GGGGGGACGC CGACTCAGTG CTCAβCCTCA CCTTCCGCAG CTTTGACCTT GCGTCCTGCG 840
ACGAGCGCGG CAGCGACCTG GTGACGGTGT ACAACACCCT GAGCCCCATG GAGCCCCACG 900
CCCTβGTGCA GTTGTGTGGC ACCTACCCTC CCTCCTACAA CCTGACCTTC CACTCCTCCC 960
AGAACGTCCT GCTCATCACA CTGATAACCA ACACTGAGCG CCGGCATCCC GβCTTTGAGG 1020
CCACCTTCTT CCAGCTGCCT AGGATGAGCA GCTβTGGAGG CCGCTTACGT AAAGCCCAGG 1080
GGACATTCAA CAGCCCCTAC TACCCAGGCC ACTACCCACC CAACATTGAC TGCACATGGA 1140
ACATTGAGGT GCCCAACAAC CAGCATGTGA AGGTGCGCTT CAAATTCTTC TACCTGCTGG 1200
AβccceecβT GCCTGCβGGC ACCTGCCCCA AGGACTACGT GGAGATCAAT GGββAGAAAT 1260
ACTGCGGAGA .GAGGTCCCAG TTCGTCGTCA CCAGCAACAG CAACAAGATC ACAGTTCGCT 1320
TCCACTCAGA TCAGTCCTAC ACCGACACCG GCTTCTTAGC TGAATACCTC TCCTACGACT 1380 CCAGTβACCC ATGCCCGGGG CAGTTCACGT GCCGCACGGβ GCGGTGTATC CGGAAGGAGC 1440
TGCGCTGTGA TββCTCGGCC βACTGCACCG ACCACAGCGA TGAGCTCAAC TGCAGTTGCG 1500
ACGCCGGCCA CCAGTTCACG TGCAAGAACA AGTTCTGCAA GCCCCTCTTC TCGGTCTGCG 1560
ACAGTGTGAA CGACTβCGGA GACAACAGCG ACGAGCAGββ GTGCAGTTGT CCGGCCCAGA 1620
CCTTCAGGTG TTCCAATGGG AAGTGCCTCT CGAAAAGCCA GCAGTGCAAT GββAAGGACG 1680
ACTGTGGGGA CGGGTCCGAC GAGGCCTCCT GCCCCAAGGT GAACGTCGTC ACTTGTACCA 1740
AACACACCTA GCGCTGCCTC AATGGGCTCT GCTTGAGCAA GGGCAACCCT GAβTGTGACG 1800
GGAAGGAG6A CTGTAGCGAC GβCTCAGATG AGAAGGACTG CGACTGTGGG CTGCGGTCAT 1860
TCACGAβACA GβCTCβTβTT GTTGGGGGCA CGGATGCGGA TGAGGGCGAG TGGCCCTGGC 1920
AGGTAAGCCT βCATGCTCTG GGCCACββCC ACATCTGCGβ TGCTTCCCTC ATCTCTCCCA 1980
ACTGGCTGGT CTCTGCCGCA CACTGCTACA TCGATGACAG AGGATTCAβG TACTCAGACC 2040
CCACGCAGTβ GACGGCCTTC CTGGGCTTGC ACGACCAGAG CCAGCGCAGC GCCCCTGGGG 2100
TGCAGGAβCG CAGGCTCAAG CGCATCATCT CCCACCCCTT CTTCAAT6AC TTCACCTTCG 2160
ACTATGACAT CGCGCTGCTG GAGCTGGAGA AACCGGCAGA GTACAGCTCC ATGGTGCGGC 2220
CCATCTGCCT GCCGGACβCC TCCCATGTCT TCCCTGCCGG CAAGβCCATC TGGGTCACGG 2280
GCTGGGGACA CACCCAβTAT GβAGGCACTG GCGCGCTGAT CCTGCAAAAG GGTGAGATCC 2340
GCGTCATCAA CCAGACCACC TGCGAβAACC TCCTGCCβCA GCAGATCACG CCGCGCATGA 2400
TGTGCGTGGβ CTTCCTCAGC GGCGGCβTGG ACTCCTGCCA GGGTGATTCC GGGGGACCCC 2460
TGTCCAGCGT GGAGGCGGAT GGGCGGATCT TCCAGGCCGG TGTGGTGAGC TGGGGAGACG 2520
GCTβCGCTCA GAGGAACAAG CCAGGCGTGT ACACAAGGCT CCCTCTGTTT CGββACTββA 2580
TCAAAGAGAA CACTCβββTA TAGGGGCCGG GGCCACCCAA ATGTβTACAC CTGCGGGGCC 2640
ACCCATCGTC CACCCCAβTG TGCACGCCTG CAGGCTGβAG ACTββACCGC TGACTGCACC 2700
AGCGCCCCCA GAACATACAC TGTGAACTCA ATCTCCAGGG CTCCAAATCT GCCTAGAAAA 2760
CCTCTCGCTT CCTCAGCCTC CAAAGTββAG CTGGGAGGTA GAAGGGGAβG ACACTGGTGG 2820
TTCTACTGAC CCAACTGGGG GCAAAGGTTT GAAGACACAG CCTCCCCCGC CAGCCCCAAG 2880
CTGGGCCGAG GCGCGTTTGT GTATATCTGC CTCCCCTGTC TGTAAGGAGC AGCβGGAACG 2940
GAGCTTCGGA GCCTCCTCAG TGAAGGTGGT GGGGCTβCCβ GATCTGGGCT GTGGGGCCCT 3000
TGGGCCACGC TCTTGAGGAA GCCCAGGCTC GGAGGACCCT GGAAAACAGA CGGGTCTGAG 3060
ACTGAAAATG GTTTACCAGC TCCCAGGTGA CTTCAGTGTG TGTATTGTGT AAATGAGTAA 3120
AACATTTTAT TTCTTTTTAA AAAAAAAAA 3149
Seq ID NO: C23 DNA Sequence
Nucleic Acid Accession ff: Eos sequence
Coding sequence: 1..2268
1 11 21 31 41 51 1 1 1 | 1 | 1 | 1 1 ATβCCCCCTT TCCTGTTGCT GGAAGCCGTC TGTGTTTTCC TGTTTTCCAG AGTGCCCCCA 60
TCTCTCCCTC TCCAGGAAGT CCATCTAAGC AAAGAAACCA TCGGGAAGAT TTCAGCTGCC 120
AGCAAAATGA TGTGGTGCTC ββCTCCACTG GACATCATGT TTCTGTTAGA TGGGTCTAAC 180
AGCGTCGGGA AAGGGAGCTT TGAAAβGTCC AAGCACTTTG CCATCACAβT CTGTGACGGT 240
CTGGACATCA GCCCCGAGAG GGTCAβAGTG GGAGCATTCC AGTTCAGTTC CACTCCTCAT 300
CTGGAATTCC CCTTGGATTC ATTTTCAACC CAACAGGAAG TGAAβGCAAG AATCAAGAGG 360
ATGGTTTTCA AAGGAGGGCG CACGGAGACG GAACTTGCTC TGAAATACCT TCTGCACAGA 420
GG6TTGCCTG GAGGCAGAAA TGCTTCTGTβ CCCCAGATCC TCATCATCCT CACTGATGGG 480
AAGTCCCAGG GGGATGTGGC ACTGCCATCC AAβCAGCTGA AGGAAAGGβG TGTCACTGTG 540
TTTGCTGTGG GGGTCAGGTT TCCCAGGTGβ GAGGAGCTGC ATGCACTGGC CAGCGAGCCT 600
AGAGββCACC ACGTGCTGTT GGCTGAGCAG GTGGAGGATG CCACCAACGG CCTCTTCAGC 660
ACCCTCAGCA GCTCGβCCAT CTGCTCCAGC GCCACGCCAG ACTGCAGGGT CGAGGCTCAC 720
CCCTGTGAβC ACAGGACGCT βGAGATGGTC CGGGAGTTCG CTGGCAATGC CCCATGCTGG 780
AGAGGATCGC GGCGGACCCT TGCGGTGCTG GCTGCACACT GTCCCTTCTA CAGCTGGAAG 840
ACAGTGTTCC TAACCCACCC TGCCACCTβC TACAGGACCA CCTGCCCAGG CCCCTGTGAC 900
TCGCAGCCCT GCCAGAATGG AGGCACATGT GTTCCAGAAG GACTGGACGG CTACCAGTGC 960
CTCTGCCCGC TGβCCTTTGG AGGGGAββCT AACTGTGCCC TGAAGCTCAβ CCTGGAATGC 1020
AGβGTCCACC TCCTCTTCCT GCTGGACAGC TCTGCGGGCA CCACTCTGGA CGGCTTCCTG 1080
CGGGCCAAAG TCTTCGTGAA GCGGTTTGTG CGβGCCGTβC TGAGCGAGGA CTCTCGGGCC 1140
CGAGTGGGTG TGβCCACATA CAGCAGβGAG CTGCTGGTGG CG6TGCCTGT GGGGGAGTAC 1200
CAGGATGTGC CTGACCTGGT CTGGAGCCTC GATGGCATTC CCTTCCGTGG TGGCCCCACC 1260
CTGACGGGCA GTGCCTTGCG GCAGGCGGCA GA6CGTGGCT TCGGGAGCGC CACCAGGACA 1320
GGCCAGGACC GGCCACGTAG AGTGGTGGTT TTβCTCACTβ AGTCACACTC CGAβGATGAG 1380
GTTGCGGGCC CAGCGCGTCA CGCAAGGGCG CGAGAGCTGC TCCTGCTGGG TGTAGGCAGT 1440
GAGGCCGTGC GββCAGAGCT GGAGGAGATC ACAGGCAGCC CAAAGCATGT GATGGTCTAC 1500
TCGGATCCTC AGβATCTGTT CAACCAAATC CCTGAGCTGC AGGGGAAβCT GTGCAGCCGG 1560
CAGCGβCCAG GGTGCCGβAC ACAAGCCCTG GACCTCGTCT TCATGTTGGA CACCTCTGCC 1620
TCA6TAGGGC CCGAGAATTT TβCTCAGATG CAGAGCTTTG TGAGAAGCTβ TGCCCTCCAG 1680
TTTGAGGTGA ACCCTGACGT GACACAβGTC GGCCTGGTGG TGTATGGCAG CCAGGTGCAG 1740
ACTGCCTTCG GβCTGβACAC CAAACCCACC CGGGCTGCGA TGCTGCGGβC CATTAGCCAG 1800
GCCCCCTACC TAβGTGGGGT GGGCTCAGCC ββCACCGCCC TGCTGCACAT CTATGACAAA 1860
GTGATGACCβ TCCAGAGGβG TGCCCGGCCT βGTGTCCCCA AAGCTGTGGT GGTGCTCACA 1920
GβCGGGAGAG GCGCAGAGGA TGCAGCCGTT CCTβCCCAβA AGCTGAGGAA CAATGGCATC 1980
TCTGTCTTGG TCGTGGGCGT GGGGCCTGTC CTAAGTGAββ GTCTβCGGAG GCTTGCAGGT 2040
CCCCGGGATT CCCTGATCCA CGTGGCAGCT TACβCCβACC TGCGGTACCA CCAGGACGTβ 2100
CTCATTGAGT GGCTGTGTGG AGAAGCCAAG CGGCCAGTCA ACCTCTGCAA ACCCAGCCCG 2160
TGCATGAATG AGGGCAGCTβ CGTCCTGCAG AATGGGAGCT ACCGCTGCAA GTGTCGGGAT 2220
GGCTGGGAGG βCCCCCACTG CGAGAACCGA TTCTTGAGAC CCCCCTGA 2268
Seq ID NO: C24 DNA Sequence
Nucleic Acid Accession ff: Eos sequence
Coding sequence: 1..2424
11 21 31 41 51
I I 1 I I I
ATGCCCCCTT TCCTGTTGCT GGAGGCCGTC TGTGTTTTCC TGTTTTCCAG AGTGCCCCCA 60 TCTCTCCCTC TCCAGGAAGT CCATGTAAGC AAAGAAACCA TCGGGAAGAT TTCAGCTGCC 120 AGCAAAATGA TGTGGTGCTC GGCTGCAGTG GACATCATGT TTCTGTTAGA TGGβTCTAAC 180
AGCGTCGGGA AAGGGAGCTT TGAAAGGTCC AAGCACTTTG CCATCACAGT CTGTGACGGT 240
CTGGACATCA GCCCCGAGAG GGTCAGAGTG GβAGCATTCC AGTTCAGTTC CACTCCTCAT 300
CTGGAATTCC CCTTGGATTC ATTTTCAACC CAACAGGAAG TGAAGGCAAG AATCAAGAGG 360
ATGGTTTTCA AAGGAGGGCG CACGGAGACβ GAACTTGCTC TGAAATACCT TCTGCACAGA 420
GGGTTGCCTG GAGGCAGAAA TGCTTCTGTG CCCCAGATCC TCATCATCGT CACTGATGGG 480
AAGTCCCAGβ GGGATGTGGC ACTGCCATCC AAGCAβCTGA AGGAAAGGGG TGTCACTGTG 540
TTTGCTGTGG GGGTCAGβTT TCCCAGGTGG GAGGAGCTGC ATGCACTGGC CAGCGAGCCT 600
AGAGGGCAGC ACGTGCTGTT GGCTGAGCAG GTβGAGβATG CCACCAACGG CCTCTTCAGC 660
ACCCTCAGCA GCTCGGCCAT CTGCTCCAGC GCCACGCCAG ACTGCAGββT CGAGGCTCAC 720
CCCTGTGAGC ACAGGACGCT 6GAGATGGTC CGGGAGTTCG CTGGCAATGC CCCATGCTGβ 780
AGAGGATCGC GGCGGACCCT TGCGGTGCTG GCTGCACACT GTCCCTTCTA CAGCTGGAAβ 840
AGAβTGTTCC TAACCCACCC TGCCACCTβC TACAGGACCA CCTGCCCAGG CCCCTGTGAC 900
TCGCAGCCCT GCCAGAATGG AG6CACATGT GTTCCAGAAG GACTGGACGG CTACCAGTGC 960
CTCTGCCCGC TGGCCTTTGG AGGGGAGβCT AACTGTGCCC TGAAGCTGAG CCTGGAATGC 1020
AGGGTCGACC TCCTCTTCCT GCTGGACAGC TCTGCGGGCA CCACTCTGGA CGGCTTCCTG 1080
CGGGCCAAAβ TCTTCGTGAA GCGGTTTGTG CGGGCCGTGC TGAGCGAGGA CTCTCGGGCC 1140
CGAGTGGGTG TGGCCACATA CAGCAGGGAG CTGCTGGTGG CGGTGCCTGT GGGGGAGTAC 1200
CAGGATGTGC CTGACCTGGT CTGGAGCCTC GATGGCATTC CCTTCCGTGG TGGCCCCACC 1260
CTGACGGGCA GTGCCTTGCG GCAGGCGGCA GAGCGTGβCT TCGGGAGCGC CACCAGGACA 1320
GGCCAGGACC GGCCACGTAG AGTGGTGGTT TTGCTCACTG AGTCACACTC CGAβGATGAG 1380
GTTGCGGGCC CAGCGCGTCA CGCAAGGGCG CGAGAGCTGC TCCTGCTGGG TGTAGGCAGT 1440
GAGGCCGTGC GGGCAGAGCT GGAGGAGATC ACAGGCAGCC CAAAGCATGT GATGGTCTAC 1500
TCCGATCCTC AGGATCTGTT CAACCAAATC CCTGAβCTGC AGGGGAAGCT GTGCAGCCGG 1560
CAGCCGCCAG GGTGCCGGAC ACAAGCCCTG GACCTCGTCT TCATGTTGβA CACCTCTGCC 1620
TCAGTAGGGC CCGAGAATTT TGCTCAGATG CAGAGCTTTG TGAGAAGCTG TGCCCTCCAG 1680
TTTGA6GTGA ACCCTGACGT GACACAGGTC GGCCTGGTββ TGTATGGCAG CCAGGTGCAG 1740
ACTGCCTTCG GGCTGGACAC CAAACCCACC CGGGCTGCGA TGCT6CGGGC CATTAGCCAG 1800 βCCCCCTACC TAGGTGGGGT GββCTCAGCC GGCACCGCCC TGCTGCACAT CTATGACAAA 1860
GTGATGACCG TCCAGAGGGβ TGCCCGGCCT GGTβTCCCCA AAβCTβTGGT GGTGCTCACA 1920
GβCGGGAGAG βCCCAGAGGA TGCAGCCGTT CCTGCCCAGA AGCTGAβGAA CAATGGCATC 1980
TCTGTCTTGG TCGTGGGCGT GGGGCCTGTC CTAAGTβAGG GTCTGCGGAG GCTTGCAGGT 2040
CCCCGGGATT CCCTGATCCA CGTGGCAGCT TACGCCGACC TGCGGTACCA CCAGGACGTG 2100
CTCATTGAβT GGCTGTGTGG AGAAGCCAAG CAGCCAGTCA ACCTCTGGAA ACCCAGCCCG 2160
TGCATGAATG AGGGCAGCTG CCTCCTGCAG AATGGGAGCT ACCGCTGCAA GTGTCG∞AT 2220
6GCTGGGAGG CCCCCCACTβ CGAGAACCGT GAGTGGAGCT CTTGCTCTGT ATGTGTGAGC 2280
CAGGGATGGA TTCTTGAGAC GCCCCTGAGG CACATGGCTC CCGTGCAGGA GGGCAGCAGC 2340
CGTACCCCTC CCAGCAACTA GAGAGAAGGC CTGGGCACTG AAATGβTGCC TACCTTCTGG 2400
AATGTCTGTG CCCCAGGTCC TTAG 2424
Seq ID NO: C25 DNA Sequence
Nucleic Acid Accession ft: XM_097386.3
Coding sequence: 142..795
11 21 31 51
CTCGCAGAAC CACCTGGACT CTGTCCGTGT CTGTCCCCCG GCCTCCAGGG CTCCTCTCCC 60
GGGACCCCCG TCCCACGCCT GGGCCCCGCG CCGGGGGAAG CGCCTGCTGC CTATCTCTGT 120
CTACCTCAGG TCTGACTTTT GATGCCAAAA TCTGAGCCCC TββGGTGCCT CTCCCCCGCC 180
TCCCGTGCAC CAGGGTCTGC AGCAGCCACT GGGGCCTGGC TGCCTGCTGC ATCTGGCGGC 240
CCTGβACCCC TGGGGCCCCC GTGCACCTGC CCACCTCGGA GCCTQ3GGAG GGGCCGTGCA 300
GGGTCβAGGG CTGGGTCGTC TCCCTCGGGC TGCGTGTGTG TGTCGGGAAT CCTβCGTGTC 360
GTGTCTGTGG GCGATCCGGC CTCCCGGCGG TGβGTGGACC TGGATTCTAA CTCAGAGGAC 420
TTGAGCCTGC TGTTAACTCC GATGATTGTA GGGACAGGCG GGGTGGCTGG GGGGTGGGCG 480
CGAGGCTGGG TCCCGGCCCA GGAGAAGGAA GTCGCTGAAG GCAGTGGCCA TGCTGGCCGT 540
GβAAATGGGA GGCGGTTGCA GAGGGTCTAT GGGGCCCGGT CCTGGATACT CGGCAGGAAG 600
CCGTGTCTGC AGAGGCTCCT CCCTGCCTCA GGTGGCCCCG TTCAACCCCA GCCGTGCCCA 660
TCTCCTβCCA CCGCCTGTCG GTGβGGGTTT AAATTCGGTG TGGCTTTCTG GGGTGCAGCT 720
CAGCACCCCC CCTTATGCAG ACTGGGAGGG GGTCGGGCAG TCCCCTCAGC CACGAGGACC 780
CTGGATGGGT TCTAGTTCAC TTGGGACCGT GGGGCCTGβC TGCGTACTGA GTGGGTGCCC 840
CACAGTCAAG GCCAACGGGG GCTCCCCCTG CTCTGAGATG TTGGGAGAAA GGCGGCTTCT 900
GGAACCTTCC GTGGGACCCG TAAGTGGCTG TCCAGAAAGG CGGGAGGGTG GGCACGGGGC 960
ACGGGGGGCA GCTGGGGTCG TTGTTAAGGG TCACGCATCT GTACAGTTGA ATTTCCTTTC 1020
TCTTATCATG TTTTACCCAC CTTGTCCCTT TTTTCCCCAA TTGTGCTTTT GCATTTTTTT 1080
CCTTGGCAAA TGTAAACTCA GCCTTTCATT CATGACGTGT GAAATTTCAG TTTCTCTGGA 1140
GTTTGTCAGA CGGCGTGGGA ACCACGCCTG AAACTCAGGT AATAGGAGGA AAAAAAAAAA 1200
AACTTAAAAA AATTTTTAAA AAACATAAAA CTACTCTCTA CCTCTGGCTG GGCCCAGCCT 1260
GTCTCGCCCT GCCCGCGGCA GGGTGGCCTG TAACAATTTC AGTTTTCGCA GAACATTCAG 1320
GTATTAAAAG GAAAAAA 1337
Seq ID NO: C26 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 95..2128
11 21 31 41 51
GGGGTAGTTT GTAβGGACGC AGCTCTCCAC GTGCGCGACT GCGAGβCTGG ACGCTACGGG 60 CTCCTGGAAA GGAGAGACAC CAβCATTTGC CACAATGCTG TCATCCACTG ACTTTACATT 120 TGCTTCCTGG GAGCTTGTGG TCCGCGTTGA CCATCCCAAT GAAGAGCAGC AGAAAGACGT 180 CACACTGAGA GTATCTGGAβ ACCTTCATGT TG6AGGAGTG ATGCTCAAGT TAGTAGAACA 240 GATCAATATA TCCCAAGACT GGTCAGACTT TGCTCTTTGG TGGGAACAGA A6CATTGCTG 300 GCTTCTGAAA ACCCACTGGA CCCTGGACAA ATATGGGGTC CAGGCAGATG CAAAGCTTCT 360 CTTCACCCCT CAGCATAAAA TGCTGCGCCT TCGTCTGCCG AATTTGAAGA TGGTGAGGTT 420 GCGAGTCAGC TTCTCAGCTG TGGTTTTTAA AGCTGTCAGT GATATCTGCA AAATCCTGAA 480 TATTAGAAGA TCAGAAGAGC TTTCCTTGTT AAAGCCGTCT GGTGACTATT TTAAGAAGAA 540 βAAGAAAAAA GACAAAAATA ATAAGGAACC CATAATTGAA GATATTCTAA ACCTGGAGAG 600
TTCTCCAACA GCTTCAGGTT CATCAβTAAG TCCTGGTTTA TACAGTAAAA CCATGACCCC 660
TATATATGAC CCCATCAATG GAACACCAGC ATCATCCACC ATGACTTGGT TCAGTGAGAC 720
CCCTTTGACG GAACAAAACT GCAGCATCCT CGCATTCAGC CAACCCCCCC AGTCCCCAGA 780
AGCACTTGCG GATATGTACC AGCCTCGGTC TCTGGTTGAT AAAGCCAAGC TCAATβCAGG 840
TTGGCTAGAC TCCTCACGCT CCCTTATGGA ACAAGGCATC CAAGAGGATG AGCAGCTβCT 900
CTTACGATTT AAATATTATT CTTTCTTCGA CTTGAATCCT AAATATGATG CTGTCCGAAT 960
AAACCAACTC TATGAGCAAG CCAGGTGGGC CATTCTCTTA GAAGAAATTG ATTGCACAGA 1020
GGAAGAAATG TTGATCTTTG CAGCTCTACA GTACCACATT AGCAAACTGT CGTTGTCTGC 1080
TGAAACACAG GATTTTGCAG GCGAGTCCGA GGTTGATGAA ATAGAAGCβG CGCTTTCTAA 1140
TTTGGAAGTA ACCCTAGAAG GTGGAAAAGC GGACAGCCTT TTGGAGGACA TTACTGATAT 1200
CCCTAAACTT GCAGATAATC TCAAATTATT TAGGCCCAAG AAGTTACTAC CAAAAGCTTT 1260
CAAACAATAT TGGTTTATCT TTAAAGACAC ATCCATAGCA TACTTTAAAA ATAAGGAACT 1320
TGAACAAGGA GAACCACTAG AAAAACTAAA TCTTAGAGGC TGCGAAGTTG TGCCCGATGT 1380
AAATGTAGCA GGAAGAAAAT TTGGAATCAA GTTACTAATC CCTGTTGCCG ATGGTATGAA 1440
TGAAATGT T TTGAGATGTG ACCATGAGAA TCAATACGCC CAATGGATGG CTGCCTGCAT 1500
GTTGGCATCG AAGGGCAAAA CCATGGCAGA CAGCTCCTAC CAGCCAGA6G TCCTCAACAT 1560
CCTTTCATTT CTGAGGATGA AAAACAGGAA CTCTGCATCT CAGGTGGCTT CCAGTCTCGA 1620
AAACATGGAT ATGAACCCAβ AATGTTTTGT GTCACCACGG TGTGCAAAAA GACACAAATC 1680
CAAACAGCTG GCCGCCCGGA TCCTGGAGGC GCACCAGAAC GTGGCCCAGA TGCCCCTGGT 1740
CGAAGCCAAG CTGCGGTTCA TCCAGGCGTG GCAGTCACTG CCTGAGTTTG GCCTCACCTA 1800
CTACCTTGTC AGATTTAAAG GAAGCAAAAA AGATGACATT CTGGGAGTTT CATATAACAβ 1860
GTTGATTAAA ATTGATGCAG CCACCGGGAT TCCAGTGACA ACATGGAGAT TCACAAATAT 1920
CAAACAGTGG AATGTAAACT GGGAAACCCG GCAGGTGGTC ATCGAGTTTG ACCAAAACGT 1980
CTTTACTGCT TTCACCTGCC TGAGTGCAGA TTGCAAGATT GTGCACGAGT ACATTGGCGG 2040
CTACATTTTC TTGTCCACCC GCTCCAAGGA CCAGAATGAA ACACTCGATG AGGACTTGTT 2100
CCACAAATTG ACCGGCGGTC AGGATTGAAA CAAGCACGCG TGCTCGGCTC ACACCAACAA 2160
GGCAAGCCAA AGGCGCCCCT CCCCAGAGGG ATCCCTAACβ TGCCCAGCAT GTAGATTCTβ 2220
GACTAACAGA CAACATACAT TCACCGCTGG TCACCCACAT CCTCATTCAA ACCCACTGCT 2280
GGCACATCCC TTTCCTTACT TTGCCCTβTβ CTACCAGCCA CGGAAGGAGC CTCTCTTGTT 2340
TTTTCTATAA AATGGGTAGG CAGGAGAAAA GCAGGTGCCC TAAGATTGCT CTAAββCCCA 2400
GCATGTGGTT ACAGTTCTCT GACTTGCAGA ACCTGCCAGG TGTATGGCTA CAAGTTATCC 2460
TCGTGCTGAT CTGTCTCATT ACTAAGTCAA TGGAGAAGAC AGAAAGGTAA AAATCACGTG 2520
TAGCAAGAAC AACTCTTATT TCACAAACTC AGGTATGAAA CGAAACGCCT GTCCTTCATG 2580
GAACTGCTTT TAGCTCCTGT CTTTTCAAAA TGGCAGAGGG AGTTCCTACA CACACTTTTT 2640
CCCTGGAβGC CAAβGTCTAG GGGTAGAAAG GGGAGGGGTG GGGCTACCAG GTAGCAGTTG 2700
ACAACCCAAG GTCAGAGGAG TGGCCCTCAG TGTCATCTGT CCACAGTGAT ACCTGCCAAG 2760
ATGACCACTG ACCCACATCT GβTCTTAGTC ATTGGTCTCC TCAGATTTCT GGGGCCACCT 2820
GCAAGCCCCA TTCCATTCCT ACAGATCTCT GAGCCACCTG TAAGTCCTTT GTGAAGATGT 2880
GGGTGACACA GGGGβACAGG AAAACCCATT TCTCAACCCA GATCCATGTC TCCACTGCTT 2940
CTACTCTGβG TTGGGATTCA 6GAAGACAGG CACAGTCCTC TCTGTTCATA GAAACACCTG 3000
CCAGTGTCAA GGATTCCAGT CAGGTGTCTA TCCCAACTGG TCAGGGAGAG AAGGGCAGAC 3060
CCATTCTCAA AGACCACCAT GTCCAAGGTC TGACAGCTCC CCACTGGCTG CCCCCACAGG 3120
GGCTTTAGGC TGGTCTGGGT CATGGGGAAG CGTCCCTCTT ATCGCTGGTC TGTGTTCTCC 3180
TGGATTTGGT ATCTATGTTG GTACGACTCC TGβCCTTTTA TCTAAAGGAC TTTGGCTTTT 3240
GTAAATCACA AGCCAATAAT AGACTTTTTT CTCCCCCTCT GTTTTTTGCT GTGTCATCTC 3300
TGCCTTGAGA CTGCCTTβAG ACAGTGCTTG CCTTGAβAGA GTGAGCCAAT TAACAGCTGC 3360
CTGAATTGTC ATTTTCCATT TTGGTTTGTT AGAGGTββGA GGGGTGGGTT TTGAGAAGGT 3420
CAAAAGCAAT ACCAGAAGTA AAGGGAAATA TCAGACAATA TTTTATTATT TTTTCATAGA 3480
TGTTCTGCCA CACAAAGAAC TTGGGGTGTA AGGATAAGGC AAAAβCTCCA ATCCCATTTT 3540
TCAGTTCTCC TAGGATGCAC CCCTCAGGGA GCCTGGCCAG AGTTCCGAGG CCCGTGAGCG 3600
TCAGCTGTTG CTTTATTTTC CATCAAAGCC CTCTGAGAAG TGAGACCTCA GCAATTCCGG 3660
GAGCCACATA GAGACAGACT TGGCAAGGGA CCCCCTGGTT CTGAGCCAGT AGCTGCCATC 3720
TGGAAATTCC TCTTTTAGCC TCTCCTTAGA GGTGAATGTG AATGAAGCCT CCCAGGCACC 3780
CGCTGAATTT CTGAGGCCTT GCTTAAAGCT CAGAAGTGGT TTAGGCATTT GGAAAATCTG 3840
GTTCACATCA TAAAGAACTT GATTTGAAAT GTTTTCTATA GAAACAAGTG CTAAGTGTAC 3900
CGTATTATAC TTGATGTTGG TCATTTCTCA GTCCTATTTC TCAGTTCTAT TATTTTAGAA 3960
CCTAGTCAGT TCTTTAAGAT TATAACTGGT CCTACATTAA AATAATGCTT CTCGATGTCA 4020
GATTTTACCT GTTTGCTGCT GAGAACATCT CTGCCTAATT TACCAAAGCC AGACCTTCAG 4080
TTCAACATGC TTCCTTAGCT TTTCATAGTT GTCTGACATT TCCATGAAAA CAAAGGAACC 4140
AACTTTGTTT TAACCAAACT TTGTTTGGTT ACAGTTTTCA GGGGAGCGTT TCTTCCATGA 4200
CACACAGCAA CATCCCAAAG AAATAAACAA GTGTGACAAA AAAAAAAAAA AACAAACCTA 4260
AATGCTACTG TTCCAAAGAG CAACTTβATG GTTTTTTTTA ATACTGAGTG CAAAAGGTCA 4320
CCCAAATTCC TATGATGAAA TTTTAAATTA ATGGGCACCT TTCAACATCA TTTGCTTCCT 4380
TATCTACAGT TGATTCAGAA ATCTGCATTT TTTATTCTTT TATATGACTT TTAAGTAAAA 4440
GATTTATATG GATTTGAAAA AAAAAAAAAA A 4471
Seq ID NO: C27 Protein Sequence Protein Accession ft: NP 005161.1
1 11 21 31 41 51
I I I I I I
MDGGTLPRSA PPAPPVPVGC AARRRPASPE LLRCSRRRRP ATAETGGβAA AVARRNERER 60
NRVKLVNLGF QALRQHVPHG GASKKLSKVE TLRSAVEYIR ALQRLLAEHD AVRNALAGGL 120
RPQAVRPSAP RGPPGTTPVA ASPSRASSSP GRGGSSEPGS PRSAYSSDDS GCEGALSPAE 180
RELLDFSSWL GGY 193
Seq ID NO: C28 DNA Sequence Nucleic Acid Accession ft: NM_017763 Coding sequence: 169..2520
11 21 31 51 AAAAAAAAAA AACTTTAGAG AAAGβAAGGG CCAAAACTAC GACTTGGCTT TCTGAAACGG 60
AAGCATAAAT GTTCTTTTCC TCCATTTGTC TGGATCTGAG AACCTGCATT TGGTATTAGC 120
TAGTGGAAGC AGTATGTATG GTTGAAGTGC ATTGCTGCAG CTGGTAGCAT GAGTβGTβGC 180
CACCAβCTGC AGCTGGCTGC CCTCTGGCCC TGGCTGCTGA TGGCTACCCT GCAGGCAGGC 240
TTTGGACGCA CAGGACTGGT ACTGGCAGCA GCGGTGGAGT CTβAAAGATC AGCAGAACAG 300
AAAGCTGTTA TCAGAGTGAT CCCCTTGAAA ATGGACCCCA CAGGAAAACT GAATCTCACT 360
TTGGAAGGTG TGTTTGCTGG TGTTGCTGAA ATAACTCCAG CACAAββAAA ATTAATGCAG 420
TCCCACCCAC TGTACCTGTG CAATGCCAGT GATGACGACA ATCTGGAGCC TGGATTCATC 480
AGCATCGTCA AGCTGGAGAG TCCTCGACGG GCCCCCCGCC CCTGCCTGTC ACTGGCTAβC 540
AAGGCTCGGA TGβCGGGTGA GCGAGGAGCC AGTGCTGTCC TCTTTGACAT CACTGAGGAT 600
CGAGCTGCTG CTGAGCAGCT GCAGCAGCCβ CTGGGGCTGA CCTGGCCAGT GGTGTTGATC 660
TGGGGTAATG ACβCTGAGAA GCTGATGGAG TTTGTGTACA AGAACCAAAA GGCCCATGTG 720
AGGATTGAGC TGAAGGAGCC CCCGGCCTGG CCAGATTATG ATGTGTGGAT CCTAATGACA 780
GTGGTGGGCA CCATCTTTGT GATCATCCTG GCTTCGGTGC TGCGCATCCG GTGCCGCCCC 840
CGCCACAGCA GβCCβGATCC GCTTCAGCAG AGAACAGCCT GGGCCATCAG CCAGCTGGCC 900
ACCAGGAGGT ACCAGβCCAG CTGCAGβCAβ βCCCGGGGTG AGTGGCCAGA CTCAGGGAGC 960
AGCTGCAGCT CAβCCCCTGT GTGTGCCATC TGTCTGGAGG AGTTCTCTGA G6GGCAGGAG 1020
CTACGGGTCA TTTCCTGCCT CCATGAβTTC CATCGTAACT GTGTGGACCC CTGGTTACAT 1080
CAGCATCGGA CTTGCCCCCT CTGCβTGTTC AACATCACAG AGGGAGATTC ATTTTCCCAG 1140
TCCCTGGGAC CCTCTCGATC TTACCAAGAA CCAGGTCGAA GACTCCACCT CATTCGCCAG 1200
CATCCCGGCC ATGCCCACTA CCACCTCCCT GCTGCCTACC TGTTGGGCCC TTCCCGGAGT 1260
GCAGTGGCTC GGCCCCCACG ACCTGGTCCC TTCCTGCCAT CCCAGGAGCC AGGCATGGGC 1320
CCTCGGCATC ACCGCTTCCC CAGAGCTGCA CATCCCCGGG CTCCAGGAGA GCAβCAβCβC 1380
CTGGCAGGAG CCCAGCACCC CTATGCACAA GGCTGGGGAA TGAGCCACCT CCAATCCACC 1440
TCACAGCACC CTGCTGCTTG CCCAGTGCCC CTACGCCGGG CCAGGCCCCC TGACAGCAGT 1500
GGATCTGGAG AAAGCTATTG CACAβAACGC AGTGGGTACC TGGCAGATGG GCCAGCCAGT 1560
GACTCCAGCT CAGGGCCCTG TCATGGCTCT TCCAGTGACT CTGTGGTCAA CTGCACGβAC 1620
ATCAGCCTAC AGGGGGTCCA TGGCAGCAGT TCTACTTTCT GCAGCTCCCT AAGCAβTβAC 1680
TTTGACCCCC TAGTGTACTG CAGCCCTAAA GGGGATCCCC AGCGAGTGGA CATβCAβCCT 1740
AGTGTGACCT CTCGGCCTCG TTCCTTGGAC TCGGTGGTGC CCACAGGβGA AACCCAGGTT 1800
TCCACCCATβ TCCACTACCA CCCCCACCGG CACCACCACT ACAAAAAGCβ 6TTCCAGTGG 1860
CATGGCAβGA AGCCTGGCCC AGAAACCGGA GTCCCCCAGT CCAGGCCTCC TATTCCTCGG 1920
ACACAGCCCC AGCCAGAβCC ACCTTCTCCT 6ATCAGCAAG TCACCGGATC CAACTCAGCA 1980
GCCCCTTCGG GβCGGCTCTC TAACCCACAβ TβCCCCAGGG CCCTCCCTGA GCCAGCCCCT 2040
GGCCCAGTTG ACGCCTCCAG CATCTGCCCC AGTACCAGCA GTCTGTTCAA CTTGCAAAAA 2100
TCCAGGCTCT CTGCCCGACA CCCACAGAGG AAAAGGCGGG GGGGTCCCTC CGAGCCCACC 2160
CCTGGCTCTC GGCCCCAGGA TGCAACTGTG CACCCAGCTT GCCAGATTTT TCCCCATTAC 2220
ACCCCCAGTG TGGCATATCC TTGGTCCCCA GAGGCACACC CCTTGATCTG TGβACCTCCA 2280 ββCCTGGACA AGAGGCTGCT ACCAGAAACC CCAGGCCCCT GTTACTCAAA TTCACAGCCA 2340
GTGTGGTTGT GCCT6ACTCC TCGCCAGCCC CTGGAACCAC ATCCACCTGG GGAβGGβCCT 2400
TCTGAATGGA GTTCTβACAC CGCAGAG∞C AβGCCATGCC CTTATCCGCA CTGCCAGGTG 2460
CTGTCGGCCC AβCCTGGCTC AGAGGAGGAA CTCGAGGAGC TGTGTGAACA G6CTGTGTGA 2520
GATGTTCAGβ CCTAGCTCCA ACCAAGAGTβ TβCTCCAGAT GTGTTTGGGC CCTACCTGGC 2580
ACAGAGTCCT GCTCCTGGGA AAGGAAAGGA CCACAGCAAA CACCATTCTT TTTGCCGTAC 2640
TTCCTAGAAG CACTGGAAGA GGACTGGTGA TGGTGGAGGG TGAGAGGβTG CCGTTTCCTG 2700
CTCCAGCTCC AGACCTTGTC TGCAGAAAAC ATCTGCAGTG CAGCAAATCC ATGTCCAGCC 2760
AGGCAACCAG CTGCTGCCTG TGGCGTGTGT GGGCTGGATC CCTTGAAGGC TGAGTTTTTG 2820
AGGGCAGAAA GCTAGCTATG GβTAGCCAGG TGTTACAAAG GTGCTGCTCC TTCTCCAACC 2880
CCTACTTGGT TTCCCTCACC CCAAGCCTCA TGTTCATACC AGCCAGTGGG TTCAGCAGAA 2940
CGCATGACAC CTTATCACCT CCCTCCTTGG GTGAGCTCTG AACACCAGCT TTGGCCCCTC 3000
CACAGTAAGG CTGCTACATC AGGGGCAACC CTGGCTCTAT CATTTTCCTT TTTTGCCAAA 3060
AGGACCAGTA GCATAGGTGA GCCCTGAGCA CTAAAAGGAG GGGTCCCTGA AGCTTTCCCA 3120
CTATAGTGTG GAGTTCTGTC CCTGAGGTGG GTACAGCAGC CTTGGTTCCT CTGGGGGTTG 3180
AGAATAAGAA TAGTGGGGAG GGAAAAACTC CTCCTTGAAG ATTTCCTGTC TCAβAGTCCC 3240
AGAGAGGTAG AAAGGAGGAA TTTCTGCTGG ACTTTATCTG ββCAβAGGAA GGATGGAATG 3300
AAGGTAGAAA AGGCAGAATT ACAGCTGAGC GGGβACAACA AAGAGTTCTT CTCTGGGAAA 3360
AGTTTTGTCT TAGAGCAAGG ATGβAAAATG GGGACAACAA AGGAAAAGCA AAGTGTGACC 3420
CTTGGGTTTG GACAGCCCAG AGGCCCAGCT CCCCAGTATA AGCCATACAG GCCAGGGAGC 3480
CACAGGAβAG TGGATTAGAG CACAAGTCTG GCCTCACTβA GTGGACAAGA GCTGATGGGC 3540
CTCATCAGGG TGACATTCAC CCCAGGGCAG CCTGACCACT CTTGGCCCCT CAGGCATTAT 3600
CCCATTTGGA ATGTGAATGT GGTGGCAAAβ TGGGCAGAGG ACCCCACCTG GGAACCTTTT 3660
TCCCTCAGTT AGTGGGGAGA CTAGCACCTA GGTACCCACA TGGGTATTTA TATCTGAACC 3720
AGACAGACGC TTGAATCAGG CACTATGTTA AGAAATATAT TTATTTGCTA ATATATTTAT 3780
CCACAAAAAA AAAAAAAAAA AA 3802
Seq ID NO: C29 Protein Sequence Protein Accession ft : NP 004280.2
1 11 21 31 41 51 1 1 | 1 | 1 | 1 1 1
MNSSAHYHVN FSQAISODVN LHEAILLCPN NTFRRDPTAR TSOSQEPFLQ LNSHTTNPEQ 60
TLPGTNLTGF LSPVDNHMRN LTSQDLLYDL DINIFDEINL MSLATEDNFD PIDVSQLFDE 120
PDSDSGLSLD SSHNNTSVIK SNSSHSVCDE GAIGYCTDHE SSSHHDLEGA VGGYYPEPSK 180
LCHLDQSDSD FHGDLTFQHV FHNHTYHLQP TAPESTSEPF PWPGKSQKIR SRYLEDTDRN 240
LSRDEQRAKA LHIPFSVDEI VGMPVDSFNS MLSRYYLTDL QVSLIRDIRR RGKNKVAAQN 300
CRKRKLDIIL NLEDDVCNLQ AKKETLKREQ AQCNKAINIM KQKLHDLYHD IFSRLRDDQβ 360
RPVNPNHYAL QCTHDGSILI VPKELVASGH KKETQKβKRK 400
Seq ID NO: C30 DNA Sequence Nucleic Acid Accession # : NM_004442 Coding sequence : 19. .2982
11 21 31 51 I I I I I I
GCCCCGGGAA GCGCAGCCAT GGCTCTGCGG AGGCTGGGGG CCGCβCTGCT βCTGCTGCCG 60
CTGCTCGCCG CCGTGGAAGA AACGCTAATG βACTCCACTA CAGCGACTGC TGAGCTGGGC 120
TGGATGGTGC ATCCTCCATC AGGGTGGGAA GAGGTGAGTG GCTACGATGA GAACATGAAC 180
ACGATCCGCA CGTACCAGGT GTGCAACGTG TTTGAGTCAA GCCAGAACAA CTGGCTACGG 240
ACCAAGTTTA TCCGGCGCCG TGGCGCCCAC CGCATCCACG TGGAGATGAA GTTTTCGGTG 300
CGTGACTGCA βCAGCATCCC CAGCGTGCCT GGCTCCTGCA AGGAGACCTT CAACCTCTAT 360
TACTATGAGG CTGACTTTGA CTCGGCCACC AAGACCTTCC CCAACTGGAT GGAGAATCCA 420
TGGβTGAAGG TGGATACCAT TGCAGCCGAC GAGAβCTTCT CCCACGTGGA CCTGGβTββC 480
CGCβTCATGA AAATCAACAC CGAGβTβCGβ AβCTTCGGAC CTβTGTCCCG CAGCGGCTTC 540
TACCTGGCCT TCCAGGACTA TGGCG6CTCC ATGTCCCTCA TCGCCGTGCG TβTCTTCTAC 600
CGCAAGTGCC CCCGCATCAT CCAβAATGCC GCCATCTTCC AGGAAACCCT GTCGGGGGCT 660
GAGAGCACAT CGCTGGTGGC TGCCCGGGGC AβCTGCATCG CCAATGCGGA AGAGGTGGAT 720
GTACCCATCA AβCTCTACTG TAACGGGGAC ββCGAGTGβC TGGTGCCCAT CGGGCGCTGC 780
ATGTGCAAAG CAGGCTTCGA GGCCGTTGAG AATGGCACCG TCTGCGGAGG TTGTCCATCT 840
GGGACTTTCA AGGCCAACCA AGGGGATGAG GCCTGTACCC ACTGTCCCAT CAACAGCCGG 900
ACCACTTCTG AAGGGβCCAC CAACTGTGTC TGCCGCAATG GCTACTACAG AGCAGACCTG 960
GACCCCCTGG ACATGCCCTG CACAACCATC CCCTCCGCGC CCCAGGCTGT GATTTCCAβT 1020
GTCAATGAGA CCTCCCTCAT GCTGGAGTGG ACCCCTCCCC GCGACTCCGG AGGCCGAGAG 1080
GACCTCGTCT ACAACATCAT CTGCAA6AGC TGTβGCTCGG GCCGGββTGC CTGCACCCGC 1140
TGCGGGGACA ATGTACAGTA CGCACCACGC CAGCTAGGCC TGACCGAβCC ACGCATTTAC 1200
ATCAGTGACC TGCTGGCCCA CACCCAGTAC ACCTTCGAGA TCCAGGCTGT GAACGGCGTT 1260
ACTGACCAβA GCCCCTTCTC GCCTCAGTTC GCCTCTGTGA ACATCACCAC CAACCAGGCA 1320
GCTCCATCGG CAGTGTCCAT CATGCATCAG GTGAGCC6CA CCGTGGACAG CATTACCCTG 1380
TCGTGGTCCC AGCCAGACCA GCCCAATGGC GTGATCCTGβ ACTATGAGCT GCAGTACTAT 1440
GAGAAGGAβC TCAGTGAGTA CAACGCCACA GCCATAAAAA GCCCCACCAA CACGGTCACC 1500
GTGCAGGGCC TCAAAGCCGG CGCCATCTAT GTCTTCCAGG TGCGGβCACG CACCGTGβCA 1560
GGCTACGGGC GCTACAGCGG CAAGATGTAC TTCCAGACCA TGACAGAAGC CGAGTACCAG 1620
ACAACCATCC AGGAGAAGTT GCCACTCATC ATCGGCTCCT CGGCCGCTGG CCTGGTCTTC 1680
CTCATTGCTG TGGTTGTCAT CGCCATCGTG TGTAACAGAA GACGGGGGTT TGAGCGTGCT 1740
GACTCGGAGT ACACGGACAA GCTGCAACAC TACACCAGTβ GCCACATGAC CCCAGGCATG 1800
AAβATCTACA TCGATCCTTT CACCTACGAG GACCCCAACG AGGCAGTGCG GGAGTTTGCC 1860
AAGGAAATTG ACATCTCCTG TGTCAAAATT βAGCAGGTGA TCGGAGCAGG GGAGTTTGGC 1920
GAGGTCTGCA GTGGCCACCT GAAGCTGCCA GβCAAGAβAG AGATCTTTGT GGCCATCAAG 1980
ACGCTCAAGT CGGGCTACAC GGAGAAGCAG CGCCGGGACT TCCTGAGCGA AGCCTCCATC 2040
ATGGGCCAGT TCGACCATCC CAACGTCATC CACCTGGAGG GTGTCGTGAC CAAGAGCACA 2100
CCTβTGATGA TCATCACCGA GTTCATGGAG AATGGCTCCC TGGACTCCTT TCTCCGGCAA 2160
AACGATββGC AGTTCACAGT CATCCAGCTG GTG6GCATGC TTCGGGGCAT CGCAGCTGGC 2220
ATGAAGTACC TGGCAGACAT GAACTATGTT CACCGTGACC TGGCTGCCCG CAACATCCTC 2280
GTCAACAGCA ACCTGβTCTG CAAGGTGTCG βACTTTGGGC TCTCACGCTT TCTAGAGβAC 2340
GATACCTCAG ACCCCACCTA CACCAGTGCC CTGGGCGGAA AGATCCCCAT CCGCTGGACA 2400
GCCCCGGAAG CCATCCAGTA CCGGAAGTTC ACCTCGGCCA GTGATGTGTβ GAGCTACGβC 2460
ATTGTCATGT GGGAGGTGAT GTCCTATGGG GAGCGGCCCT ACTGβGACAT GACCAACCAG 2520
GATGTAATGA ATGCCATTGA GCAGGACTAT CGGCTGCCAC CGCCCATGGA CTGCCCGA6C 2580
GCCCTGCACC AACTCATGCT GGACTGTTGG CAGAAGGACC GCAACCACCG GCCCAAβTTC 2640
GGCCAAATTG TCAACACGCT AGACAAGATG ATCCGCAATC CCAACAGCCT GAAAGCCATG 2700
GCGCCCCTCT CCTCTGGCAT CAACCTGCCG CTGCTGGACC GCACGATCCC CGACTACACC 2760
AGCTTTAACA CGGTGGACGA GTGβCTβGAG GCCATCAAGA TGGβGCACTA CAAGGAGAGC 2820
TTCGCCAATG CCGGCTTCAC CTCCTTTGAC GTCGTGTCTC AGATβATGAT GGAGGACATT 2880
CTCCGGGTTG GGCTCACTTT GGCTGGCCAC CAGAAAAAAA TCCTβAACAC TATCCAGGTG 2940
ATGCGGGCGC AGATGAACCA GATTCAGTCT GTGGAGGTTT GACATTCACC TGCCTCGGCT 3000
CACCTCTTCC TCCAAGCCCC GCCCCCTCTG CCCCACGTGC CGGCCCTCCT GGTGCTCTAT 3060
CCACTGCAGG GCCAGCCACT CCCCAGGAGG CCACGGGCCA CGGGAAGAAC CAAGCGGTGC 3120
CAGCCACGAG ACGTCACCAA GAAAACATGC AACTCAAACG ACGGAAAAAA AAAGGGAATG 3180
GGAAAAAAGA AAACAGATCC TGGβAGGGGG CGGGAAATAC AAGGAATATT TTTTAAAGAG 3240
GATTCTCATA AGGAAAGCAA TGACTGTTCT TGCGGGGGAT AAAAAAGGGC TTG68AGATT 3300
CATβCGATGT GTCCAATCGG AGACAAAAGC AGTTTCTCTC CAACTCCCTC TGGGAAGGTG 3360
ACCTGGCCAG AβCCAAGAAA CACTTTCAGA AAAACAAATG TGAAGGGGAG AGACAGGGGC 3420
CGCCCTTGGC TCCTGTCCCT GCTGCTCCTC TAGGCCTCAC TCAACAACCA AGC6CCTGGA 3480
GGACGGGACA GATGGACAGA CAGCCACCCT GAGAACCCCT CTGGβAAAAT CTATTCCTGC 3540
CACCACTGGG CAAACAGAAG AATTTTTCTG TCTTTGGAGA GTATTTTAGA AACTCCAATG 3600
AAAGACACTG TTTCTCCTβT TββCTCACAG GGCTGAAAGG GGCTTTTGTC CTCCTGGGTC 3660
AGGGAGAACG CGGGGACCCC AGAAAGGTCA GCCTTCCTGA GGATGGGCAA CCCCAGGTCT 3720
GCAGCTCCAG GTACATATCA CGCGCACAβC CTGGCAGCCT GGCCCTCCTG GTGCCCACTC 3780
CCGCCAGCCC CTGCCTCGAG GACTGATACT GCAGTGACTG CCGTCAGCTC CGACTGCCGC 3840
TGAGAAGGGT TGATCCTGCA TCTGGGTTTG TTTACAGCAA TTCCTGGACT CGβGGβTATT 3900
TTGGTCACAG GGTGGTTTTG GTTTAGGGGG TTTGTTTGTT GGβTTGTTTT TTGTTTTTTG 3960
GTTTTTTTTA ATGACAATGA AGTGACACTT TGACATTTCC TACCTTTTGA GGACTTGATC 4020
CTTCTCCAGG AAGAAGGTGC TTTCTGCTTA CTGACTTAGG CAATACACCA AGGGCβANAT 4080
TTTATATGCA CATTTCTGGA TTTTTTTATA CGGTTTTCAT TGACACTCTT CCCTCCTCCC 4140
ACCTGCCACC AGGCCTCACC AAAGCCCACT GCCATGGGGC CATCTGGGCC ATTCAGAGAC 4200
TGGAGTGAGA TTTGGGTGTG GAGGGGGAGG CCCCAAGGTG GAGGAGCTTC CCACTCCAGG 4260
ACTGTTβATG AAAGGGACAC ATTGAGGAGG AAGTGGGCTC TGAGGCTGCA GGGCTGGAAG 4320
TCCTTGCCCA CTTCCCACTC TCCTGCCCCA ATCTATCTAG TACTTCCCAG GCAAATAGGC 4380
CCCTTTGAGG CTCCTGAGTG CCCTCAGATG GTCAAAACCC AGTTTTCCCT CTGGGAGCCT 4440
AAACCAGGCT GCATCGGAGG CCAGGACCCG GATCATTCAC TGTGATACCC TGCCCTCCAG 4500
AGβGTGCGCT CAGAGACACG GGCAAGCATG CCTCTTCCCT TCCCTGGAGA GAAAGTGTGT 4560
GATTTCTCTC CCACCTCCTT CCCCCCACCA GACCTTTGCT GGGGCTAAAG GTCTTGGCCA 4620
TGGGGACGCC CTCAGTCTAG GGATCTGGCC ACAGACTCCC TCCTGTGAAC CAACACAGAC 4680
ACCCAAGCAG AGCAATCAGT TAGTGAATTG βAATTCCCCA AGTCTTTGCT ATTGTβAATA 4740
GTGCTGCAAT AAACATACGT GTGCATGTGT CTTTATAGTA GAATGATCTA TAATCCTCTG 4800
GGTATGTACC CAGTAATGβG ATTGCTGGGT CAAATGGTTT TTCTGGTTCT AGATCCTTGA 4860
GGAATTGCCA CACTGTCTTT CACAATGGTT GAACTAATTT ACACTCCTAC CAACAGTGTA 4920
AAAGTCTTCC TGTTTCTCCA CATCCTCTCC AGCATCTGTT GTTTCCTGAC TTTTTAATGA 4980 TTGCCATTCT AACTβGTGTG AGATGGTATC TCATTGTGGG TTTGATTTGC ATTTCTCTAA 5040 TGACCAGTGA AGATGAGCTT TTTTTCATAT GTTTGTTGβC CACATGTTTG TTCTTTCTTT 5100 TGAGAAGTGT CTGTTCATAA CCTTCACCAA TTTTTGATGA GGTTGTTTGT TCTTTTCTTG 5160 TAAACTTAAT GAAATAAAGC ATGAAGACAA GATTAGAAGA AAAAGAATGA AAAGGAACAA 5220 ACAAAGCGTC CAAGAAATAT GGGACTATGT GACAAGAACA AACTTACGTT TGACTGGTGT 5280 GCTGAAAATG ACAGGGAGAA TGAAACCAAG TTGGAAAACA CTCTTCAGGA TATTATCCAG 5340 GAGAACTTCT CCAACCTAGC AAGACAGACC AACβTTCAAA TTCAGGAAAT ACAGAGAACA 5400 CCCAAAGATA TTTCTCGAGA AGAGCAACCC GAAGACACAT AATTGTCAGA TTCACCAAGβ 5460 TTGAAATGAA GGAAAAAATG CTAAGGGCAG CCAGAGAGAA AGGTCAGGTT ACTCACAAAA 5520 GGAAGCCCAT CAGACTAACA GCAβATCTCT CTβCAGAAAC CCTACAACCT AGAAβAGAGT 5580 GGGGACCAAT ATTCAACATT CACAAAβAAA AGAATTTTCA ATCCAGAATT TCATATCCAG 5640 CCAAACTAAG CTTCATAAGC AAAGGAβAAA TAAAATCCTT TACAGACAAG CAAATCCTGG 5700 GAGATTTTβT CACCACCAGG CCTGCCTTAC AAGACATCCT GAAGGAAGCA CTAAATATGG 5760 AAAAβAAAAA CTGGTGCCAG CCACTGCAAA AAATACCAAA TTGTAGAGAC CATTGACACT 5820 ATGAAGAAAC CGTGTCAACT AATGGGCAAA ATAACCAGCT AβTATCATAA TGACAGGATC 5880 AGATTCACAC ATAACAATAT TAACCTTATA TCTAAATGGG CTAAATCCCC CAATTAAAAG 5940 ACGCAGACTG GCAAATTGGT TAAAGAGTCA AGACTCATTG GTGTGCCGTA TTCAGGAGAC 6000 CCATCTCACG TGCAAAGACA CACATAGGCT CAGAGTAAAA GGGATACAGG GGAATTC 6057
Seq ID NO: C31 DNA Sequence
Nucleic Acid Accession ff: NM_031942.1
Coding sequence: 145..1260
11 21 31 41 51
I I I I I
CCCGAGCCCC GCCCCTCCGG GCCCGGGTCG GCGCGCCCAG CCTGCCAGCC GCGCTGCTGC 60
TGCTCCTCCT GCTGTGGGAC CGCTβACCGC GCGGCTGCTC CGCTCTCCCC GCTCCAAGCG 120
CCGATCTGGG CACCCGCCAC CAGCATGGAC GCTCGCCGCG TGCCGCAGAA AGATCTCAGA 180
GTAAAGAAGA ACTTAAAGAA ATTCAGATAT GTGAAGTTGA TTTCCATGGA AACCTCGTCA 240
TCCTCTGATG ACAGTTGTGA CAGCTTTGCT TCTGATAATT TTGCAAACAC GAGGGTGCAG 300
TCAGTTCGGG AAGGCTβTAG GACCCGCAGC CAGTGCAGGC ACTCTGGACC TCTCAGGGTG 360
GCGATGAAGT TTCCAGCβCG GAGTACCAGG GGAGCAACCA ACAAAAAAGC AGAGTCCCGC 420
CAGCCCTCAG AGAATTCTGT GACTGATTCC AACTCCGATT CAGAAGATGA AAGTGGAATG 480
AATTTTTTGG AGAAAAGGGC TTTAAATATA AAGCAAAACA AAGCAATGCT TGCAAAACTC 540
ATGTCTGAAT TAGAAAGCTT CCCTGGCTCG TTCCGTGGAA GACATCCCCT CCCAGGCTCC 600
GACTCACAAT CAAGβAβACC GCGAAGGCGT ACATTCCCGG GTGTTGCTTC CAGGAGAAAC 660
CCTGAACGGA GAGCTCGTCC TCTTACCAGG TCAAGGTCCC GβATCCTCGG GTCCCTTGAC 720
GCTCTACCCA TGGAGGAβGA GGAGGAAGAG GATAAGTACA TGTTGGTGAG AAAGAGGAAG 780
ACCGTGGATG GCTACATGAA TGAAGATGAC CTGCCCAGAA GCCGTCGCTC CAGATCATCC 840
GTGACCCTTC CGCATATAAT TCGCCCAGTG GAAGAAATTA CAGAGGAGGA GTTGGAGAAC 900
GTCTGCAGCA ATTCTCGAGA GAAGATATAT AACCGTTCAC TGGGCTCTAC TTβTCATCAA 960
TGCCGTCAGA AGACTATTGA TACCAAAACA AACTGCAGAA ACCCAGACTG CTGGGGCGTT 1020
CGAGGCCAGT TCTGTGGCCC CTGCCTTCGA AACCGTTATG GTGAAGAGGT CAGGGATGCT 1080
CTGCTGGATC CGAACTGGCA TTGCCCβCCT TGTCGAGGAA TCTGCAACTG CAGTTTCTGC 1140
CGGCAGCGAG ATGGACGGTG TβCGACTGGG GTCCTTGTGT ATTTAGCCAA ATATCATGGC 1200
TTTGGGAATG TGCATGCCTA CTTGAAAAGC CTGAAACAGG AATTTGAAAT GCAAGCATAA 1260
TATCTGGAAA ATTTGCTGCC TGCCTTCTAC TTCTCAAATC TTTCTTGTAA AAGTTTCCAA 1320
TTTTTTCACT GAAACCTGAG TTAAAAATCT TGATGATCAG CCTGTTTCAT AAGAAACTCC 1380
AATCAAGTTA ATCTTAGCAG ACATGTGTTT CTGGAGCATC ACAGAAGGTA TATTGCTAGT 1440
TACACTTTGC CCTCCTGCAG TTTCTTCTCT GCTCCCAACC CCCATCTCAT AGCATCCCCC 1500
TCTATTTCCA ATGCTCCTCT CCAACCGCTT AGTTTCTGAA TTTCTTTTAA ATTACACTTT 1560
TATGAAAGCA TATTTTATTT ACTTGGTGTT GAAATAGCCC TCATAAAACC TAAGCACTTG 1620
GAAACACAAT AATAGTATTA ACTAACTAGA TCTATTGAAT TTCAGAGAAG AGCCTTCTAA 1680
CTTβTTTACA CAAAAACGAG TATGATTTAG CACTCATACT AGTTβAAATT TTTAATAGAA 1740
TCAAGGCACA AAAGTCTTAA AACCATGTGG AAAAATTAGG TAATTATTGC AGATTGATGT 1800
CTCTCAATCC CATGTATTGC GCTTATGTTA CAAGTTGTTG TCACAGTTGA GACTTAATTT 1860
CTCCTAATTT CTTCTGCCCG AAGGGTAAGT GGTGCGTCCA GCTTACACGA TCATAATTCA 1920
AAGGTTGGTG GGCAATGTAA TACTTAATTA AAATAATGAT GGAAGAGCTA TCTGGAGATT 1980
ATGAGTAAGC TGATTTGAAT TTTCAGTATA AAACTTTAGT ATAATTGTAG TTTGCAAAGT 2040
TTATTTCAGT TCACATGTAA GGTATTGCAA ATAAATTCTT GGACAATTTT GTATGGAAAC 2100
TTGATATTAA AAACTACTCT GTGGTTCTTT GCAGTTTCTT GTAAATTTAT AAACCAGGCA 2160
CAAGGTTCAA GTTTAGATTT TAAGCACTTT TATAACAATG ATAAGTGCCT TTTTGGAGAT 2220
GTAACTTTTA GCAGTTTGTT AACCTGACAT CTCTGCCAGT CTAGTTTCTG GGCAGGTTTC 2280
CTGTGTCAGT ATTCCCCCTC CTCTTTGCAT TAATCAAGGT ATTTGGTAGA GGTGGAATCT 2340
AAGTGTTTGT ATGTCCAATT TACTTGCATA TGTAAACCAT TGCTGTGCCA TTCAATGTTT 2400
GATGCATAAT TGGACCTTGA ATCGATAAGT GTAAATACAG CTTTTGATCT GTAATGCTTT 2460
TATACAAAAG TTTATTTTAA TAATAAAATG TTTGTTCTAA AAAAAAAAAA 2510
Seq ID NO: C32 DNA Sequence Nucleic Acid Accession #: NM_012445.1 Coding sequence: 276..1271
11 21 31 41 51
I I I I I
GCACβAGGGA AGAGGGTGAT CCGACCCGGG GAAGGTCGCT GGGCAGGGCG AGTTGGGAAA 60 GCGGCAGCCC CCGCCGCCCC CGCAGCCCCT TCTCCTCCTT TCTCCCACGT CCTATCTGCC 120 TCTCGCTGGA GGCCAGGCCG TGCAGCATCG AAGACAGGAG GAACTGGAGC CTCATTGGCC 180 GβCCCβGβGC GCCGGCCTCG GGCTTAAATA GGAGCTCCGG GCTCTGGCTG GGACCCβACC 240 GCTGCGGGCC GCGCTCCCGC TGCTCCTGCC GGGTGATGGA AAACCCCAGC CCGGCCβCCG 300 CCCTGGGCAA GGCCCTCTGC ecTCTccTcc TGGCCACTCT CGGCGCCGCC GGCCAGCCTC 360 TTGGGGGAGA GTCCATCTGT TCCGCCAGAG CCCCGGCCAA ATACAGCATC ACCTTCACGG 420 GCAA6TGGAG CCAGACGGCC TTCCCCAAGC AGTACCCCCT GTTCCGCCCC CCTGCGCAGT 480 GGTCTTCGCT GCTGGGGGCC GCGCATAGCT CCGACTACAG CATGTGGAGG AAGAACCAGT 540 ACGTCAGTAA CGGGCTGCGC GACTTTβCGG AGCGCGGCGA GGCCTGGβCG CTGATGAAGG 600 AGATCGAGGC ββCCGGGGAG GCGCTGCAGA βCGTGCACGC GGTGTTTTCG GCGCCCGCCβ 660
TCCCCAGCGG CACCGGGCAG ACGTCGGCGβ AGCTGGAGGT GCAGCGCAGG CACTCGCTGG 720
TCTCGTTTGT GGTGCGCATC βTGCCCAβCC CCGACTGGTT CGTGGGCGTG GACAGCCTGβ 780
ACCTGTβCGA CGGGGACCGT TGGCGGGAAC AGGCGGCGCT GGACCTGTAC CCCTACGACG 840
CCGGGACGGA CAGCGGCTTC ACCTTCTCCT CCCCCAACTT CGCCACCATC CCGCAGGACA 900
CGGTGACCGA GATAACGTCC TCCTCTCCCA GCCACCCGGC CAACTCCTTC TACTACCCGC 960
GGCTGAAGGC CCTGCCTCCC ATCGCCAGGG TGACACTGGT GCGGCTGCGA CAGAGCCCCA 1020
GGGCCTTCAT CCCTCCCGCC CCAGTCCTGC CCAGCAβGGA CAATGAGATT GTAGACAGCG 1080
CCTCAGTTCC AGAAACCCCG CTGGACTGCG AGβTCTCCCT GTGGTCGTCC TGGGGACTGT 1140
10 GCGGAGGCCA CTGTGGGAGG CTCGGGACCA AβAGCAGβAC TCGCTACGTC CGGGTCCAGC 1200
CCCCCAACAA CGβGAGCCCC TGCCCCGAGC TCGAAGAAGA GGCTGAGTGC GTCCCTGATA 1260
ACTGCGTCTA AGACCAβAGC CCCGCAGCCC CTGGGGCCCC CGGAGCCATG GGGTGTCGGG 1320
GGCTCCTGTG CAGGCTCATG CTGCAG6CGG CCGAGβCACA GGGGGTTTCG CGCTGCTCCT 1380
GACCGCGGTG AGβCCGCGCC GACCATCTCT GCACTGAAGG GCCCTCTGGT GGCCGGCACG 1440
15 GGCATTGGGA AACAGCCTCC TCCTTTCCCA ACCTTGCTTC TTAGGGGCCC CCGTGTCCCG 1500
TCTGCTCTCA GCCTCCTCCT CCTGCAGGAT AAAGTCATCC CCAAGGCTCC AGCTACTCTA 1560
AATTATGGTC TCCTTATAAG TTATTGCTGC TCCAGGAGAT TGTCCTTCAT CGTCCAGGGG 1620
CCTGGCTCCC ACGTβGTTGC AGATACCTCA GACCTGGTGC TCTAGGCTGT GCTGAGCCCA 1680
CTCTCCCGAG GGCGCATCCA AGCGGGGGCC ACTTGAGAAβ TGAATAAATG GGGCGGTTTC 1740
20 GGAAGCGTCA GTGTTTCCAT GTTATGβATC TCTCTGCGTT TGAATAAAGA CTATCTCTGT 1800
TGCTCAC 1807
Seq ID NO: C33 DNA Sequence Nucleic Acid Accession #: Eos sequence •ZD Coding sequence: 1..1314
1 11 21 31 41 51 1 1 1 1 | 1 | 1 I 1 I 1
ATGTTACAGG ATCCTGACAG TGATCAACCT CTGAACAGCC TCGATGTCAA ACCCCTGCGC 60
30 AAACCCCGTA TCCCCATGGA GACCTTCAGA AAGGTGGGβA TCCCCATCAT CATAGCACTA 120
CTGAGCCTGG CGAGTATCAT CATTGTGGTT GTCCTCATCA AGGTGATTCT GGATAAATAC 180
TACTTCCTCT GCGGGCAGCC TCTCCACTTC ATCCCGAGGA AGCAGCTGTG TGACGGAGAG 240
CTGGACTβTC CCTTGGGGGA GGACGAGGAG CACTGTGTCA AGAGCTTCCC CGAAGGGCCT 300
GCAβTGGCAG TCCGCCTCTC CAAGGACCGA TCCACACTGC AGGTGCTGGA CTCGGCCACA 360
35 GGGAACTGGT TCTCTGCCTG TTTCGACAAC TTCACAGAAG CTCTCGCTGA GACAGCCTGT 420
AGGCAGATGG GCTACAGCAG CAAACCCACT TTCAGAβCTG TGGAGATTGG CCCAGACCAG 480
GATCTGGATG TTGTTGAAAT CACAGAAAAC AGCCAGGAGC TTCGCATGCG GAACTCAAGT 540
GGGCCCTGTC TCTCAGGCTC CCTGGTCTCC CTGCACTGTC TTGCCTGTGG GAAβAGCCTG 600
AAGACCCCCC GTGTGGTGGG TGGGGAG6AG GCCTCTGTGG ATTCTTGGCC TTGGCAGβTC 660
40 AGCATCCAGT ACGACAAACA GCACGTCTGT GGAGGGAGCA TCCTβGACCC CCACTGGβTC 720
CTCACGGCAG CCCACTGCTT CAGGAAACAT ACCGATβTGT TCAACTGGAA ββTGCGGβCA 780
GGCTCAGACA AACTGGGCAG CTTCCCATCC CTGGCTGTGG CCAAGATCAT CATCATTGAA 840
TTCAACCCCA TGTACCCCAA AGACAATGAC ATCGCCCTCA TGAAGCTGCA GTTCCCACTC 900
AGTTTCTCAG βCACAGTCAG GCCCATCTGT CTGCCCTTCT TTGATGAGGA βCTCACTCCA 960
45 GCCACCCCAC TCTGGATCAT TGGATGGGGC TTTACGAAGC AGAATGGAGG GAAGATGTCT 1020
GACATACTGC TGCAGGCGTC AGTCCAGGTC ATTGACAGCA CACGGTGCAA TGCAGACGAT 1080
GCGTACCAGG GGGAAGTCAC CGAGAAGATG ATGTGTGCAG GCATCCCGGA AGGGGGTGTG 1140
GACACCTGCC AGGGTGACAG TGGTGGGCCC CTGATGTACC AATCTGACCA GTGGCATGTG 1200
GTGGGCATCG TTAGCTGGGG CTATGβCTGC GGGGGCCCGA GCACCCCAGG AGTATACACC 1260
50 AAGGTCTCAG CCTATCTCAA CTGGATCTAC AATGTCTGGA AGGCTGAGCT GTAA 1314
Seq ID NO: C34 DNA Sequence
Nucleic Acid Accession #: NM_003045.
Coding sequence: 148..2037
55
11 21 31
CGATCCTGCC GGAGCCCCGC CGCCGCCGβC TTGGATTCTG AAACCTTCCT TGTATCCCTC 60
CTGAGACATC TTTGCTGCAA GATCGAGGCT GTCCTCTGGT GAGAAGGTGG TβAGGCTTCC 120
60 CGTCATATTC CAGCTCTGAA CAGCAACATG GββTGCAAAG TCCTGCTCAA CATTGGGCAG 180
CAGATGCTGC GGCGGAAGGT GGTGGACTGT AGCCGGβAGG AGACGCGGCT GTCTCGCTGC 240
CTβAACACTT TTGATCTGGT βGCCCTCβGG GTGGGCAGCA CACTGGGTGC TGGTGTCTAC 300
GTCCTGGCTG GAGCTGTGGC CCGTGAGAAT GCAGGCCCTG CCATTGTCAT CTCCTTCCTG 360
ATCGCTGCGC TGGCCTCAGT GCTGGCTG6C CTGTGCTATG GCGAGTTTGG TGCTCGGGTC 420
65 CCCAAGACGG GCTCAGCTTA CCTCTACAGC TATGTCACCG TTGGAGAGCT CTGGGCCTTC 480
ATCACCGGCT GGAACTTAAT CCTCTCCTAC ATCATCGGTA CTTCAAGCGT AGCGAβGGCC 540
TGGAGCGCCA CCTTCGACGA GCTGATAGβC AGACCCATCG GGGAGTTCTC ACGGACACAC 600
ATGACTCTGA ACGCCCCCGG CGTGCTGGCT GAAAACCCCe ACATATTCGC AGTGATCATA 660
ATTCTCATCT TGACAGGACT TTTAACTCTT GGTGTGAAAG AGTCGGCCAT GGTCAACAAA 720
70 ATATTCACTT GTATTAACGT CCTGGTCCTG GβCTTCATAA TGGTGTCAGG ATTTGTGAAA 780
GGATCGGTTA AAAACTGGCA GCTCACGGAG GAGβATTTTG GGAACACATC AGGCCGTCTC 840
TGTTTGAACA ATGACACAAA AGAAGββAAG CCCGGTGTTG GTGGATTCAT GCCCTTCGGG 900
TTCTCTGGTG TCCTGTCGGG GGCAGC6ACT TGCTTCTATG CCTTCGTGGG CTTTGACTGC 960
ATCGCCACCA CAGGTGAAGA GGTGAAGAAC CCACAGAAGG CCATCCCCGT GGGGATCGTβ 1020
75 GCGTCCCTCT TGATCTGCTT CATCGCCTAC TTTGGGGTGT CG6CTGCCCT CACGCTCATG 1080
ATGCCCTACT TCTGCCTβGA CAATAACAGC CCCCTGCCCG ACGCCTTTAA GCACGTGGGC 1140
TGGGAAGGTG CCAAGTACGC AGTGGCCGTG GGCTCCCTCT GCGCTCTTTC CGCCAGTCTT 1200
CTAGGTTCCA TGTTTCCCAT GCCTCGGβTT ATCTATGCCA TGGCTGAGGA TGGACTGCTA 1260
TTTAAATTCT TAGCCAACGT CAATGATAGβ ACCAAAACAC CAATAATCGC CACATTAGCC 1320
80 TCGGGTβCCG TTGCTGCTGT βATGGCCTTC CTCTTTGACC TGAAGGACTT GGTGGACCTC 1380
ATGTCCATTG GCACTCTCCT GβCTTACTCG TTGGTGGCTG CCTGTGTGTT GGTCTTACGG 1440
TACCAGCCAG AGCAGCCTAA CCTGGTATAC CAGATGGCCA GTACTTCCGA CGAGTTAGAT 1500
CCAGCAGACC AAAATGAATT GβCAAβCACC AATGATTCCC AGCTGGGGTT TTTACCAGAG 1560
GCAGAGATGT TCTCTTTGAA AACCATACTC TCACCCAAAA ACATGGAGCC TTCCAAAATC 1620 TCTGGGCTAA TTGTGAACAT TTCAACCAGC CTTATAGCTG TTCTGATCAT CACCTTCTGC 1680
ATTGTGACCG TGCTTGGAAG GβAGGCTCTC ACCAAAGGGG CGCTGTGGGC AGTCTTTCTG 1740
CTCGCAGGGT CTGCCCTCCT CTGTGCCGTG GTCACGGGCG TCATCTGGAG βCAGCCCGAβ 1800
AGCAAGACCA AGCTCTCATT TAAGGTTCCC TTCCTGCCAG TβCTCCCCAT CCTGAGCATC 1860
TTCGTGAACG TCTATCTCAT GATGCAGCTG GACCAGGGCA CCTCGGTCCG GTTTGCTGTG 1920
TGGATβCTGA TACGCTTCAT CATCTACTTT GGCTATG6CC TGTGβCACAG CGAGGAGGCG 1980
TCCCTGGATG CCGACCAAGC AAGGACTCCT GACGGCAACT TβGACCAGTG CAAGTGACGC 2040
ACAGCCCCGC CCCCCGGAGG TGGCAGCAGC CCCGAGGGAC GCCCCCAGAG GACCGGGAGG 2100
CACCCCACCC TCCCCACCAG TGCAACAGAA ACCACCTGCG TCCACACCCT CACTGCA 2157
Seq ID NO : C35 DNA Sequence
Nucleic Acid Accession ff : NM_002776.1
Coding sequence : 82 . .912
1 11 21 31 41 51 1 1 | 1 | 1 | 1 | 1 J 1 ACCAGCGGCA GACCACAGGC AGGGCAGAGG CACGTCTGGG TCCCCTCCCT CCTTCCTATC 60
GβCGACTCCC AGATCCTGGC CATGAGAGCT CCGCACCTCC ACCTCTCCGC cβccTCTβec 120
GCCCGGGCTC TβGCGAAGCT GCTGCCGCTG CTGATGGCGC AACTCTGGGC CGCAGAGGCG 180
GCGCTGCTCC CCCAAAACGA CACGCGCTTG GACCCCGAAβ CCTATGGCGC CCCGTGCGCG 240
CGCGGCTCGC AGCCCTGGCA GGTCTCGCTC TTCAAceecc TCTCGTTCCA CTGCGCGGGT 300
GTCCTGGTGG ACCAGAGTTG GGTGCTGACG GCCGCGCACT GCGβAAACAA βCCACTCTββ 360
GCTCGAGTAG GGGATGATCA CCTGCTGCTT CTTCAGGGCG AGCAGCTCCG CCGGACGACT 420
CGCTCTGTTG TCCATCCCAA GTACCACCAG GGCTCAGGCC CCATCCTGCC AAGGCGAACG 480
GATGAGCACG ATCTCATGTT GCTAAAβCTG GCCAGGCCCG TAGTGCCGGG GCCCCGCGTC 540
CGGβCCCTGC AGCTTCCCTA CCGCTGTGCT CAGCCCGGAG ACCAGTGCCA GGTTGCTGGC 600
TGβββCACCA CGGCCGCCCG GAGAGTGAAG TACAACAAGG GCCTβACCTC CTCCAGCATC 660
ACTATCCTGA GCCCTAAAGA GTGTGAGGTC TTCTACCCTG GCβTβGTCAC CAACAACATG 720
ATATGTGCTG GACTGGACCG GGGCCAGGAC CCTTGCCAGA GTGACTCTGG AGGCCCCCTG 780
GTCTGTGACG AGACCCTCCA AββCATCCTC TCGTGGGGTG TTTACCCCTG TGGCTCTGCC 840
CAGCATCCAG CTGTCTACAC CCAGATCTGC AAATACATGT CCTGGATCAA TAAACTCATA 900
CGCTCCAACT GATCCAGATG CTACGCTCCA GCTGATCCAG ATGTTATGCT CCTGCTGATC 960
CAGATGCCCA GAββCTCCAT CGTCCATCCT CTTCCTCCCC AGTCGGCT6A ACTCTCCCCT 1020
TGTCTGCACT βTTCAAACCT CTGCCGCCCT CCACACCTCT AAACATCTCC CCTCTCACCT 1080
CATTCCCCCA CCTATCCCCA TTCTCTGCCT GTACTGAAGC TβAAATβCAβ βAAGTGGTGG 1140
CAAAGGTTTA TTCCAGAGAA GCCAGGAAGC CGGTCATCAC CCAGCCTCTG AGAGCAGTTA 1200
CTGGGGTCAC CCAACCTGAC TTCCTCTGCC ACTCCCCGCT GTGTGACTTT GGβCAAGCCA 1260
AGTGCCCTCT CTGAACCTCA GTTTCCTCAT CTGCAAAATG GGAACAATGA CGTGCCTACC 1320
TCTTAGACAT GTTGTGAGGA GACTATGATA TAACATGTGT ATGTAAATCT TCATGTGATT 1380
GTCATGTAAG GCTTAACACA GTGGGTGGTG AGTTCTGACT AAAGGTTACC TβTTGTCβTβ 1440
AAAAAAAAAA AAAA 1454
Seq ID NO : C36 DNA Sequence Nucleic Acid Accession ft : XM_095088 Coding sequence: 1. .4074
11 21 31
ATGACCCGGG CCGCGACAGC CGAGCCGGGC CGCGTGTCTC CCGCCTCGCC CGCGCGCAGC 60
ACGGCGGGCC TGCCGCGCGC CTTCCTGCAG AGCCTβCGCA CCCTGTTAGA CATCCTGGAC 120
GACTGβCAGC GCGβCTCCGT GCACCTGCGA GAGATCCAGT CCCTCTGGGT CGAAGCeCGG 180
GAGCTβCCAA GCGGGGTGCT GGAGGGCCTG AGCCAGCGGC GCGGGCCGCA GCCGGGAβCA 240
GCTGTACGCT CCCGCCGAGG CGGCGCAGTG CCCCGCGβGG CCCGAβCGGT TCCAGAGCGC 300
TβCGCTGβAA CGGAGACCCG GCGCGGACGC AGGTGCAGCG GCCTGCAGCG CCTTGGAGGC 360
GGATTCAGGG GATGCCCGGC GGACCCCTGT GCCCGAGGGG AACACCGGAG GCACACCATC 420
ACCAGCGGCG TGGACTGCGG CCTβCTGAAG CAGATGAAGG AGCTGGAGCA GGAGAAGGAG 480
GTGCTGCTAC AGGGTTTGGA GATGATGGCG CAGGGCCGCβ ATTGGTACCA GCAGCAGCTG 540
CAACAAGTGC AGGAGCGCCA GTGCCGCCTG GGCCAGAGCA GAGCCAGCGC CGACTTTGGG 600
GCCGTGGGGA GCCCTCGCCC ACTGGGACββ CTACTGCCCA AGGTACAGGA GGTGGCCCGG 660
TGGCTGGGGG AGCTGCTGGC TGAGGCCTGT GCCβGTCCGG CCCTGCCCAC ATCCTCCTCC 720
GGGCCCCCTT GCTCTGCCCT GACGTCCACC TCGTCCCCGG GCTββCAβCA GCACATCATC 780
CTCATGCTGA AGGAGCAGAA CCGACTCCTC ACCCAGGAGG TβACCGAGAA GAGTGAGCGC 840
ATCACGCAGC TGGAGCAGAA GTCGGCGCTC ATTAAGCAGC TATTTGAGGC CCGCGCCCTG 900
AGCCAGCAGG ATGGGGGCCT GTCCCCGGCT GGCCCCCACA TTGAGCCCTT GACTCGGTTT 960
CGGCTTCCGG TGCTGACATG GGCTGGGGCT CTCTTGAGTC CGCATAGTCC GCAGCTACTA 1020
CTGCCGCTGT CAGCGGACAG TGGGGGACCC CTCCACGAGT TACCAGATAC CTGGTTTCCA 1080
GCGGTGCTGC TTTGGGTCCC ATCTCCAGβG AAAAGAACTG CTCACGCCAG GCTGCACTTC 1140
CACCAAAGGC CAGCAGAGGG CG∞T∞CAG CTCGGATβCG GCGCTGAGGC TGCGCCCGAG 1200
ACCTGCGGGA CGCTGCCCCA CTTTβAβTCC CACAAAACAA CCTGTGAGCC TGACTCCCTC 1260
GGAGGGCCCT GTCCCCAGGA GGGGGATCGC AGCTGGA6CC ACCTGGGCGC AGCGTTTGAT 1320
GTGGCACCTG CAGTGGCCAA AGTGACACCC AACCGTGAGG ACGCTβCAββ GAGTCGGCAC 1380
GGAGACATCT GTCCCCTCTG TCCCAAGGGA CTGTTGACAT TCA6A6ACAT AGCTATAGAA 1440
TTCTCTCTGG CGGAGTGGCA ATGCCTGGAT CATGCTCAGC AGAATTTATA TAGAGATGTG 1500
ATGTTAGAGA ACTACAGAAA CCTGTTCTCC CTGGGTATGA CTGTCTCTAA GCCAGACTTG 1560
ATCGCCTGTC TGGAGCAAAA TAAAGAGCCC CAGAATATAA AGAβAAATβA GATGGCAGCC 1620
AAACACCCAG TTACATGTTC TCATTTCAAC CAAGACCTTC AβCCAGAGCA GAGCATAAAA 1680
GATTCACTCC AAAAAGTAAT ACCAAGAACA TATGGAAAAT GTGGACATGA GAATTTACAA 1740
TTAAAAAAAT GTTGTAAAAG AGTAGATGAG TGTGAGGTGC ACAAAGGAGG TTATAATCAC 1800
CTTAACCAAT GTTTGTCAAA TACCCAAAAC AAAATATTTC AGACTCATAA ATGTOTCAAA 1860
GTCTTCAGTA AATTTTCAAA TTCCAATAGA CACAATGCAA GATATACTGG AAAGAAACAT 1920
TTGAAATGTA AAAAATATGG CAAATCATTT TGCATGTTTT CACACCTAAA TCAACATCAG 1980
ATAATTCATA CTAAGGAGAA GTCCTACAAA TGTGAAGAAT GTGGCAAATC CTTTAACCAC 2040
TCCTCAAGCG GTACTACACA TAAAAGAATT CTTACTGGAG AGAAACCCTA CAGATGTGAG 2100
GAATGTGGCA AAGCCTTTAG GTGGCCCTCA AACCTTACTA GACATAAGAG AATTCACACT 2160 βGAGAGAAAC CCTACGCATG TGAAGAATGT GGCCAAGCCT TTAGGCGCTC CTCAACACTT 2220
ACTAACCACA AGAGAATTCA TACTGGAGAG AGAGCCTACA AATGTGAAGA ATGTGGCAAA 2280
GCCTTTAGCG TATCCTCAGC CCTCATTTAC CACAAGAGAA TTCATACTGG AGAGAAACCC 2340
TACACATGTG AAGAATGTGG CAAAGCCTTT AACTGCTCCT CGACTCTTAA GACACATAAG 2400
ATAATTCATA CTGGAGAGAA ACCCTACACA TGTGAAGAAT GTGGCAGAAC CTTTAACTGG 2460
TCCTCAACTG TAAAGGCACA TAAGAGAATT CATACTGGAG AGAAACCATA CAAATGTGAA 2520
GAATGTGACA AAGCTTTTAA GTGGCATTCA AGTCTTGCTA AACATAAGAT AATTCACACT 2580
GGAGAGAAAC CCTACAAATG CAGTGACAGC AAAGCCTTAG CCAAATCATC AGAAGTGCAA 2640
AAGGTCTACT CTGGAGATGG GGAAAATGGA ATCCGTGTAC ATAAGAAAAA GGAGACACAG 2700
GGCTGGCTTG TGAGAAACAA GAACGAAAAT AGAACAGGGC TGTTCCAGAT CCGGβCTGCC 2760
GTGAGACCTA ACAGGGACCC TTCATGGGGA CAGCAAGAAG GTTCACTGAC TGACCCAATT 2820
CAGAGGAAGG AGGAACCTGA CCTTCAAAAT CACTATGACC ATCAGAATGC CTTAGAAGAT 2880
CAAAGAAATA CTGGAGTGGG TGGACTGTTG ACATTCAGAG ATGTAβTCAT AGAATTCTCT 2940
CTGGAGGAGT GGCAATGCCT GGATCACGCT CAGCAGAATT TATATAGAGA TGTGAT6TTA 3000
6AGAACTACA GAAACCTGGT CTCCCTGGGT ATTGCTGTCT CTAAGCCAGA CTTGATCACC 3060
TGTCTGGAGC AAAATAAAGA GCCTTGGAAT ATAAAGAGAA ATGAGATGGT AACCAAACAC 3120
CCAGACCTTC CGCCAGAGCT AGGCATAAAA GATTCACTCC AAAAAGTAAT ACCAAGAAGA 3180
TATGGAAAAA βTGGACATGA CAATTTACAA GTAAAAACAT GTAAAAβCAT CGGTGAGTGT 3240
GAGGTGCAAA AAGGAGGTTG TAATGAAGTT AACCAATGTT TGTCAACTAC CCAAAACAAA 3300
ATATTTCAGA CTCATAAATG TGTCAAAGTC TTCGGCAAAT TTTCAAATTC CAATAGACAT 3360
AAGACAAGAC ATACTGGAAA GAAACATTTC AAATGTAAAA AATATGGCAA ATCATTTTGC 3420
ATGGTTTCAC AACTACATCA ACATCAGATA ATTCATACTA GGGAGAATTC CTACCAATGT 3480
GAAGAATGCG GCAAACCCTT CAACTGCTCT TCAACCCTTT CTAAACATAA AAGAATTCAT 3540
ACTGGAGAGA AACCCTACAG ATGTGAGGAA TGTGGCAAAG CTTTTACCTG GTCCTCAACC 3600
CTTACTAAAC ATAGGAGAAT TCATACTGGA GAAAAACCCT ACACATGTGA AGAATGTGGC 3660
CAAGCCTTTA GCCGCTCCTC AACACTTGCT AACCACAAGA GAATTCATAC TGGAGAGAAA 3720
CCATACACAT GTGAAGAATG TGGCAAAGCC TTTAGCTTAT CCTCATCCCT CACTTACCAC 3780
AAGAGAATTC ATACTGGAGA GAAACCCTAC ACATGTGAAG AATGTGGCAA AGCCTTTAAC 3840
TGCTCCTCAA CCCTTAAGAA ACATAAGATA ATTCATACTG GAGAGAAACC CTACAAATGT 3900
AAAGAATGTG GGAAAGCCTT TGCCTTCTCC TCAACTCTTA ATACTCATAA GAGGATTCAT 3960
ACTGGAGAGG AACCCTACAA ATGTGAAGAA TGTGACAAAG CTTTTAAGTG GTCCTCAAGT 4020
CTTGCTAATC ATAAGAGTAT GCATACTGGA GAGAAACCCT ACAAATGTGA ATAA 4074
Seq ID NO : C37 DNA Sequence Nucleic Acid Accession ff : NM 032044
Coding sequence : 182 . .658
1 11 21 31 41 51
I I I I I I
AAGATATAAA AGCTCCAGAA ACGTTGACTG GGACCACTGG AGACACTGAA GAAGGCAGGβ 60
GCCCTTAGAG TCTTGGTTGC CAAACAGATT TGCAGATCAA GGAGAACCCA GβAGTTTCAA 120
AGAAGCGCTA GTAAGGTCTC TGAGATCCTT GCACTAGCTA CATCCTCAGG GTAGGAGGAA 180
GATGGCTTCC AGAAGCATGC GGCTGCTCCT ATTGCTGAGC TGCCTGGCCA AAACAGGAGT 240
CCTGGGTGAT ATCATCATGA GACCCAGCTG TGCTCCTGGA TGGTTTTACC ACAAGTCCAA 300
TTGCTATGGT TACTTCAGGA AGCTβAGGAA CTGGTCTGAT GCCGAGCTCG AGTGTCAGTC 360
TTACGGAAAC GGAGCCCACC TGGCATCTAT CCTGAGTTTA AAGGAAGCCA GCACCATA6C 420
AGAGTACATA AβTGGCTATC AGAGAAGCCA GCCGATATGG ATTGGCCTGC ACGACCCACA 480
GAAGAGGCAG CAGTGGCAGT GGATTβATGG GGCCATGTAT CTGTACAGAT CCTGGTCTGG 540
CAAGTCCATG GGTGGGAACA AGCACTGTGC TGAGATGAGC TCCAATAACA ACTTTTTAAC 600
TTGGAGCA6C AACGAATGCA ACAAGCGCCA ACACTTCCTG TGCAAGTACC GACCATAGAG 660
CAAGAATCAA GATTCTGCTA ACTCCTGCAC AβCCCCGTCC TCTTCCTTTC TGCTA6CCTG 720
GCTAAATCTG CTCATTATTT CAGAGGGGAA ACCTAGCAAA CTAAGAGTβA TAAGGGCCCT 780
ACTACACTGβ CTTTTTTAβG CTTAGAGACA GAAACTTTAG CATTGGCCCA GTAGTGGCTT 840
CTAGCTCTAA ATGTTTGCCC CGCCATCCCT TTCCACAGTA TCCTTCTTCC CTCCTCCCCT 900
GTCTCTGGCT GTCTCGAGCA GTCTAGAAGA GTGCATCTCC AGCCTATGAA ACAGCTGGGT 960
CTTTGGCCAT AAGAAGTAAA GATTTGAAGA CAGAAGGAAG AAACTCAGGA GTAAGCTTCT 1020
AGACCCCTTC AGCTTCTACA CCCTTCTGCC CTCTCTCCAT TGCCTGCACC CCACCCCAGC 1080
CACTCAACTC CTGCTTGTTT TTCCTTTGGC CATAGGAAGG TTTACCAGTA GAATCCTTGC 1140
TAGGTTGATβ TGGGCCATAC ATTCCTTTAA TAAACCATTG TGTACATAAG AAAAAAAAAA 1200
Seq ID NO : C38 DNA Sequence
Nucleic Acid Accession ff : Eos sequence
Coding sequence : 52 . .3042
1 11 21 31 41 51
I I 1 I I I
GCTCACCCAG GAAAAATATG CAATCGTCCC ATTGATATAC AGGCCACTAC AATGGATβGA 60
GTTAACCTCA GCACCGAGGT TGTCTACAAA AAAGGCCAGG ATTATAGβTT TGCTTGGTAC 120
GACCGGGGCA GAGCCTGCCG βAβCTACCβT GTACGGTTCC TCTGTGGβAA GCCTGTGAGG 180
CCCAAACTCA CAGTCACCAT TGACACCAAT GTGAACAGCA CCATTCTGAA CTTGGAGGAT 240
AATGTACA6T CATGGAAACC TGGAGATACC CTGGTCATTG CCAGTACTGA TTACTCCATβ 300
TACCAGGCAG AAGAGTTCCA GGTβCTTCCC TGCAGATCCT GCGCCCCCAA CCAGGTCAAA 360
GTGGCAGGGA AACCAATGTA CCTGCACATC GGGGAβGAGA TAGACGGCGT GGACATGCGG 420
GCGGAGGTTG GGCTTCTGAG CCGGAACATC ATAGTGATGG GGGAGATGGA GGACAAATGC 480
TACCCCTACA GAAACCACAT CTCCAATTTC TTTGACTTCG ATACCTTTGG GGGCCACATC 540
AAGTTTGCTC TGGGATTTAA GGCAGCACAC TTGGAGGGCA CGGAGCTGAA GCATATGGGA 600
CAGCAβCTGG TGGGTCAGTA CCCGATTCAC TTCCACCTGG CCGGTGATGT AβACGAAAGG 660
GβAGGTTATG ACCCACCCAC ATACATCAGG GACCTCTCCA TCCATCATAC ATTCTCTCGC 720
TGCGTCACAG TCCATGGCTC CAATGGCTTG TTGATCAAGG ACGTTGTGGG CTATAACTCT 780
TTGGGCCACT GCTTCTTCAC βGAAGATGGG CCGGAGGAAC GCAACACTTT TGACCACTGT 840
CTTGGCCTCC TTGTCAAGTC TGGAACCCTC CTCCCCTCGG ACCCTGACAG CAAGATGTGC 900
AAGATGATGA CAGGAGACTC CTACCCAGGG TACATCCCCA AGCCCAGGCA AGACTGCAAT 960
GCTGTGTCCA CCTTCTGGAT GGCCAATCCC AACAACAACC TCATCAACTG TGCCGCTGCA 1020
GGATCTGAGG AAACTGGATT TTGGTTTATT TTTCACCACG TACCAACGGG CCCCTCCGTG 1080 GGAATGTACT CCCCAGGTTA TTCAGAGCAC ATTCCACTGG GAAAATTCTA TAACAACCGA 1140
GCACATTCCA ACTACCGGGC TGGCATGATC ATAGACAACG GAGTCAAAAC CACCGAβGCC 1200
TCTGCCAAGG ACAAGCGGCC GTTCCTCTCA ATCATCTCTG CCAGATACAG CCCTCACCAG 1260
GACGCCGACC CGCTGAAGCC CCGββAGCCG GCCATCATCA GACACTTCAT TGCCTACAAβ 1320
AACCAGGACC ACGGGβCCTG GCTGCGCGGC GβGβATβTGT GGCTGGACAG CTGCCGGTTT 1380
GCTGACAATG GCATTCGCCT GACCCTGGCC AGTββTGGAA CCTTCCCβTA TGACGACGβC 1440
TCCAAGCAAG AGATAAAGAA CAGCTTGTTT GTTββCGAGA GTGGCAACGT GGGGACGGAA 1500
ATGATGGACA ATAGGATCTG GGGCCCTGGC GGCTTGGACC ATAGCG6AAG GACCCTCCCT 1560
ATAGGCCAGA ATTTTCCAAT TAGAGGAATT CAGTTATATG ATGGCCCCAT CAACATCCAA 1620
AACTGCACTT TCCGAAAGTT TGTGGCCCTG GAββGCCGGC ACACCAGCβC CCTCGCCTTC 1680
CCCCTGAATA ATGCCTGGCA GAGCTGCCCC CATAACAACG TGACCGGCAT TβCCTTTGAG 1740
GACGTTCCGA TTACTTCCAG AGTGTTCTTC GGAGAGCCTG GGCCCTGGTT CAACCAGCTβ 1800
GACATGGATG GGGATAAGAC ATCTGTGTTC CATGACGTCG ACGGCTCCGT GTCCGAGTAC 1860
CCTGGCTCCT ACCTCACGAA GAATGACAAC TGGCTGGTCC GGCACCCAGA CTGCATCAAT 1920 βTTCCCGACT GGAGAGGGGC CATTTGCAGT GGGTGCTATG CACAGATGTA CATTCAAGCC 1980
TACAAGACCA GTAACCTβCC AATGAAGATC ATCAAGAATG ACTTCCCCAG CCACCCTCTT 2040
TACCTGGAGG GGβCβCTCAC CAGGAGCACC CATTACCAGC AATACCAACC GGTTGTCACC 2100
CTGCAGAAGG GCTACACCAT CCACTGGGAC CAGACGGCCC CCGCCGAACT CGCCATCTβG 2160
CTCATCAACT TCAACAAGGβ CβACTGGATC CGAGTGGGGC TCTGCTACCC GCGAGGCACC 2220
ACATTCTCCA TCCTCTCGβA TGTTCACAAT CGCCTβCTGA AGCAAACGTC CAAGACβGβC 2280
GTCTTCGTGA GGACCTTGCA GATGGACAAA GTGGAGCAGA GCTACCCTGG CAGGAGCCAC 2340
TACTACTGGG ACGAGGACTC AGGGCTGTTG TTCCTGAAGC TGAAAGCTCA GAACGAβAβA 2400 βAGAAGTTTG CTTTCTGCTC CATGAAAGGC TGTGAGAGGA TAAAGATTAA AGCTCTGATT 2460
CCAAAGAACG CAGGCGTCAG TGACTGCACA GCCACAGCTT ACCCCAAGTT CACCGAGAGG 2520
GCTGTCGTAG ACGTGCCGAT GCCCAAGAAG CTCTTTGGTT CTCAGCTβAA AACAAAGGAC 2580
CATTTCTTGG AGGTGAAGAT GGAGAGTTCC AAGCAGCACT TCTTCCACCT CTGGAACGAC 2640
TTCGCTTACA TTGAAGTGGA TGGGAAGAAG TACCCCAGTT CGGAGGATGG CATCCAGGTG 2700
GTGGTGATTG ACGGGAACCA AGGGCGCGTG GTGAβCCACA CGAGCTTCAG GAACTCCATT 2760
CTGCAAGGCA TACCATGGCA GCTTTTCAAC TATGTGGCGA CCATCCCTGA CAATTCCATA 2820
GTGCTTATGG CATCAAAGGG AAGATACGTC TCCAGAGGCC CATGGACCAG AGTGCTGβAA 2880
AAGCTTGGGG CAGACAGGGβ TCTCAAGTTG AAAGAGCAAA TGGCATTCGT TGGCTTCAAA 2940
GGCAGCTTCC GGCCCATCTG GGTGACACTG GACACTGAGβ ATCACAAAGC CAAAATCTTC 3000
CAAGTTGTGC CCATCCCTGT GGTGAAGAAG AAGAAGTTGT GAGGACAGCT GCCGCCCCGT 3060
GCCACCTCGT GGTAGACTAT GACGGTGACT CTTGβCAGCA GACCAGTGGG GGATGGCTCG 3120
GTCCCCCAGC CCCTGCCAGC ACCTGCCTGG GAAβGCCGTG TTTCAGCCCT GATGGGCCAA 3180
GGGAAGGCTA TCAGAGACCC TGGTGCTGCG ACCTGCCCCT ACTCAAGTGT CTACCTGβAβ 3240
CCCCTGGGGC GGTGCTGGCC AATGCTGGAA ACATTCACTT TCCTGCAGCC TCTTGGGTGC 3300
TTCTCTCCTA TCTGTGCCTC TTCAGTGGGG GTTTGGGGAC CATATCAGGA GACCTGGGTT 3360 βTGCTGACAG CAAAGATCCA CTTTGGCAGG AGCCCTGACC CAGCTAGGAG GTAGTCTββA 3420 ββGCTGGTCA TTCACAGATC CCCATGGTCT TCAGCAβACA AGTGAGGGTG GTAAATGTAG 3480
GAGAAAGAGC CTTGGCCTTA AGGAAATCTT TACTCCTGTA AGCAAGAGCC AACCTCACAG 3540
GATTAGβAGC TGGGGTAGAA CTGGCTATCC TTGGGGAAβA GGCAAGCCCT GCCTCTGGCC 3600
GTGTCCACCT TTCAGGAβAC TTTGAGTGGC AGGTTTGGAC TTGGACTAGA TGACTCTCAA 3660
AGGCCCTTTT AGTTCTGAGA TTCCAGAAAT CTGCTGCATT TCACATGGTA CCTββAACCC 3720
AACAGTTCAT GGATATCCAC TGATATCCAT GATGCTGGGT GCCCCAβCGC ACACGGGATG 3780
GAGAGβTGAG AACTAATGCC TAGCTTGAGG GGTCTGCAGT CCAGTAβββC AGGCAGTCAG 3840
GTCCATGTGC ACTGCAATGC CAGGTGGAβA AATCACAGAG AGGTAAAATG GAGGCCAGTG 3900
CCATTTCAGA GGGGAβGCTC AGGAAGβCTT CTTGCTTACA GGAATGAAGG CTGGGGGCAT 3960
TTTGCTGGGG GGAGATGAGG CAGCCTCTGG AATGGCTCAG GGATTCAGCC CTCCCTGCCG 4020
CTGCCTGCTG AAGCTGGTβA CTACGGGGTC GCCCTTTGCT CACGTCTCTC TGβCCCACTC 4080
ATGATGGAGA AGTGTGGTCA GAGGGGAGCA ATGGGCTTTG CTGCTTATGA GCACAGAGGA 4140
ATTCAGTCCC CAGGCAGCCC TGCCTCTGAC TCCAAGAGGG TGAAGTCCAC AGAAGTGAβC 4200
TCCTGCCTTA GGGCCTCATT TGCTCTTCAT CCAGGGAACT GAGCACAGGG GGCCTCCAGG 4260
AGACCCTAGA TGTGCTCGTA CTCCCTCGGC CTGGGATTTC AGAGCTGGAA ATATAGAAAA 4320
TATCTAGCCC AAACCCTTCA TTTTAACAGA TGGGGAAAGT GAGCCCCCAA GATGGGAAAG 4380
AACCACACAG CTAAGGGAGG GCCTGGGGAG CCCCACCCTA GCCCTTGCTG CCACACCACA 4440
TTGCCTCAAC AACCGGCCCC AGAGTGCCCA GGCACTCCTG AGGTAGCTTC TGGAAATGGG 4500
GACAAGTCCC CTCGAAGGAA AGGAAATGAC TAGAGTAGAA TGACAGCTAG CAGATCTCTT 4560
CCCTCCTGCT CCCAGCGCAC ACAAACCCGC CCTCCCCTTG GTGTTGGCGG TCCCTGTGGC 4620
CTTCACTTTG TTCACTACCT GTCAGCCCAG CCTGGGTGCA CAGTAGCTGC AACTCCCCAT 4680
TGGTGCTACC TGGCTCTCCT GTCTCTGCAG CTCTACAGGT GAGGCCCAGC AGAGGGAGTA 4740
GGGCTCGCCA TGTTTCTGβT GAGCCAATTT GGCTGATCTT GGGTGTCTGA ACAGCTATTβ 4800 ββTCCACCCC AGTCCCTTTC AGCTGCTGCT TAATGCCCTG CTCTCTCCCT GGCCCACCTT 4860
ATAGAGAGCC CAAAGAGCTC CTGTAAGAGG GAGAACTCTA TCTGTGGTTT ATAATCTTGC 4920
AGGAGGCACC AGAGTCTCCC TGGGTCTTGT GATGAACTAC ATTTATCCCC TTTCCTGCCC 4980
CAACCACAAA CTCTTTCCTT CAAAGAGGGC CTGCCTGGCT CCCTCCACCC AACTGCACCC 5040
ATGAGACTCG GTCCAAGAGT CCATTCCCCA GGTGGGAGCC AACTGTCAGG GAGGTCTTTC 5100
CCACCAAACA TCTTTCAGCT GCTGGGAGGT GACCATAGGG CTCTGCTTTT AAAGATATGG 5160
CTGCTTCAAA GGCCAGAGTC ACAβGAAGGA CTTCTTCCAG GGAGATTAGT GGTGATGGAG 5220
AGGAGAGTTA AAATGACCTC ATGTCCTTCT TGTCCACGGT TTTGTTGAβT TTTCACTCTT 5280
CTAATβCAAG GGTCTCACAC TGTGAACCAC TTAGGATGTG ATCACTTTCA ∞TGGCCAGG 5340
AATCTTGAAT GTCTTTGGCT CAGTTCATTT AAAAAAGATA TCTATTTGAA AGTTCTCAGA 5400
GTTGTACATA TGTTTCACAG TACAGGATCT GTACATAAAA GTTTCTTTCC TAAACCATTC 5460
ACCAAGAGCC AATATCTAGG CATTTTCTTG GTAGCACAAA TTTTCTTATT GCTTAGAAAA 5520
TTGTCCTCCT TGTTATTTCT GTTTGTAAGA CTTAAGTGAG TTAGGTCTTT AAGGAAAGCA 5580
ACGCTCCTCT βAAATGCTTG TCTTTTTTCT GTTGCCGAAA TAGCTGGTCC TTTTTCGGGA 5640
GTTAGATGTA TAGAGTGTTT GTATGTAAAC ATTTCTTGTA GGCATCACCA TGAACAAAGA 5700
TATATTTTCT ATTTATTTAT TATATGTGCA CTTCAAGAAβ TCACTβTCAβ AβAAATAAAG 5760
AATTGTCTTA AATGTCAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAA 5808
Seq ID NO : C39 DNA Sequence Nucleic Acid Accession ft : NM_014373 Coding sequence : 322 . 1338 1 11 21 31 41 51
1 1 1 1 1 1 | 1 | 1 1 1 GTGGCCTCGA GGTGGTGGCA GGGCCGCCCC CTGCAGTCCG GAβACGAACG CACGGACCGG 60
GCCTCCGGAG CCAGGTTCGG CTGGAAGGAA CCGCTCTCGC TTCβTCCTAC ACTTGCGCAA 120
ATGTCTCCGA GCTTACTCAC ATAGCATATT GGTATATCAA AATGAAATGC AAβGAACCAA 180
AAATAACATA ATTGAAGGCA GTAAAAGTGA AATTAAATAG βAAGATCATC AGTCAAGGAA 240
GACCCACTββ AGAGGACAGA AAATGAAGCA GTGTTTTATC ATβTGTATTT CAGCAGGTCT 300
TCTTβAAATT TAACTAAAAA TATGACTGCT CTCTCTTCAG AGAACTGCTC TTTTCAGTAC 360
CAGTTACGTC AAACAAACCA GCCCCTAGAC GTTAACTATC TGCTATTCTT GATCATACTT 420
GGGAAAATAT TATTAAATAT CCTTACACTA GGAATGAGAA GAAAAAACAC CTCTCAAAAT 480
TTTATGGAAT ATTTTTGCAT TTCACTAGCA TTCGTTGATC TTTTACTTTT CGTAAACATT 540
TCCATTATAT TGTATTTCAG GβATTTTGTA CTTTTAAGCA TTAGGTTCAC TAAATACCAC 600
ATCTGCCTAT TTACTCAAAT TATTTCCTTT ACTTATGGCT TTTTGCATTA TCCAGTTTTC 660
CTGACAGCTT GTATAGATTA TTβCCTβAAT TTCTCTAAAA CAACCAAGCT TTCATTTAAβ 720
TGTCAAAAAT TATTTTATTT CTTTACAGTA ATTTTAATTT GβATTTCAGT CCTTGCTTAT 780
GTTTTGGGAG ACCCAGCCAT CTACCAAAGC CTGAAGGCAC AGAATGCTTA TTCTCGTCAC 840
TGTCCTTTCT ATGTCAGCAT TCAGAGTTAC TGGCTGTCAT TTTTCATGGT GATGATTTTA 900
TTTGTAGCTT TCATAACCTG TTGGGAAGAA GTTACTACTT TGGTACAGGC TATCAGGATA 960
ACTTCCTATA TGAATGAAAC TATCTTATAT TTTCCTTTTT CATCCCACTC CAGTTATACT 1020
GTGAGATCTA AAAAAATATT CTTATCCAAG CTCATTGTCT GTTTTCTCAG TACCTGGTTA 1080
CCATTTGTAC TACTTCAGGT AATCATTβTT TTACTTAAAG TTCAGATTCC AGCATATATT 1140
GAGATGAATA TTCCCTGGTT ATACTTTβTC AATAGTTTTC TCATTGCTAC AGTGTATTGG 1200
TTTAATTGTC ACAAGCTTAA TTTAAAAGAC ATTGGATTAC CTTTGGATCC ATTTGTCAAC 1260
TGGAAGTGCT GCTTCATTCC ACTTACAATT CCTAATCTTG AGCAAATTGA AAAGCCTATA 1320
TCAATAATβA TTTCTTAATA TTATTAATTA AAAGTTACAG CTGTCATAAG ATCATAATTT 1380
TATGAACAGA AAGAACTCAG GACATATTAA AAAATAAACT GAACTAAAAC AACTTTTGCC 1440
CCCTGACTGA TAGCATTTCA GAATGTGTCT TTTGAAGGGC TATACCAβTT ATTAAATAGT 1500
GTTTTATTTT AAAAACAAAA TAATTCCAAG AAGTTTTTAT AGTTATTCAG GGACACTATA 1560
TTACAAATAT TACTTTGTTA TTAACACAAA AAGTGATAAG AGTTAACATT TGGCTATACT 1620
GATGTTTGTG TTACTCAAAA AAACTACTGG ATGCAAACTG TTATGTAAAT CTGAGATTTC 1680
ACTGACAACT TTAAGATATC AACCTAAACA TTTTTATTAA ATGTTCAAAT GTAAGCAAGA 1740
AAAAAAAAA 1749
Seq ID NO: C40 DNA Sequence Nucleic Acid Accession tf: BC012089 Coding sequence: 1..2571
1 11 21 31 41 51 1 1 | 1 | 1 |1 | 1 1 1 ATGGCCCTCG TACTCGGCTC CCTGTTGCTβ CTCGGGCTGT GCGGGAACTC CTTTTCAGGA 60
GGGCAGCCTT CATCCACAGA TGCTCCTAAG GCTTGGAATT ATGAATTGCC TGCAACAAAT 120
TATGAGACCC AAGACTCCCA TAAAGCTββA CCCATTGGCA TTCTCTTTGA ACTAGTGCAT 180
ATCTTTCTCT ATGTGGTACA GCCGCGTGAT TTCCCAGAAG ATACTTTGAβ AAAATTCTTA 240
CAGAAGGCAT ATGAATCCAA AATTGATTAT GACAAGATTG TCTACTATGA AGCAGGGATT 300
ATTCTATGCT GTGTCCTGGG GCTGCTGTTT ATTATTCTGA TGCCTCTGGT GGGGTATTTC 360
TTTTGTATGT GTCβTTGCTG TAACAAATGT GGTGGAβAAA TGCACCAGCG ACAGAAβGAA 420
AATGGGCCCT TCCTGAGGAA ATGCTTTGCA ATCTCCCTGT TβGTGATTTG TATAATAATA 480
AGCATTGGCA TCTTCTATGG TTTTGTGGCA AATCACCAGG TAAGAACCCG GATCAAAAGG 540
ACTCGGAAAC TGGCAGATAG CAATTTCAAG GACTTGCGAA CTCTCTTGAA TGAAACTCCA 600
GAGCAAATCA AATATATATT GGCCCA6TAC AACACTACCA AGGACAAβGC GTTCACAGAT 660
CTGAACAGTA TCAATTCAGT GCTAGGAGβC GGAATTCTTG ACCGACTGAG ACCCAACATC 720
ATCCCTGTTC TTGATGAGAT TAAGTCCATβ βCAACAGCGA TCAAGβAβAC CAAAGAGGCG 780
TTGGAGAACA TGAACAGCAC CTTGAAGAGC TTGCACCAAC AAAGTACACA GCTTAGCAGC 840
AGTCTGACCA βCGTGAAAAC TAGCCTGCGG TCATCTCTCA ATGACCCTCT GT6CTTGGTG 900
CATCCATCAA GTGAAACCTG CAACAGCATC AGATTGTCTC TAAGCCAGCT GAATAGCAAC 960
CCTGAACTGA GGCAGCTTCC ACCCGTGGAT GCAGAACTTG ACAACGTTAA TAACGTTCTT 1020
AGGACAGATT TGGATGGCCT GGTCCAACAG GGCTATCAAT CCCTTAATGA TATACCTGAC 1080
AGAGTACAAC GCCAAACCAC GACTGTCGTA GCAGGTATCA AAAGGGTCTT GAATTCCATT 1140
GGTTCAGATA TCGACAATGT AACTCAGCGT CTTCCTATTC AGGATATACT CTCAGCATTC 1200
TCTGTTTATG TTAATAACAC TGAAAGTTAC ATCCACAGAA ATTTACCTAC ATTGGAAGAG 1260
TATGATTCAT ACTGGTGGCT GGGTGGCCTβ GTCATCTGCT CTCTGCTβAC CCTCATCGTG 1320
ATTTTTTACT ACCTGGGCTT ACTGTGTGβC GTβTGCGGCT ATGACAGβCA TGCCACCCCG 1380
ACCACCCGAG GCTGTGTCTC CAACACCGβA βGCGTCTTCC TCATGGTTGG AGTTGGATTA 1440
AGTTTCCTCT TTTGCTGGAT ATTGATGATC ATTGTβGTTC TTACCTTTGT CTTTGGTGCA 1500
AATGTGGAAA AACTGATCTG TGAACCTTAC ACGAGCAAGG AATTATTCCG GGTTTTGGAT 1560
ACACCCTACT TACTAAATGA AGACTGGGAA TACTATCTCT CTGGGAAGCT ATTTAATAAA 1620
TCAAAAATGA AGCTCACTTT TGAACAAGTT TACAGTGACT GCAAAAAAAA TAGAGGCACT 1680
TACGβCACTC TTCACCTGCA GAACAGCTTC AATATCAGTG AACATCTCAA CATTAATGAG 1740
CATACTGGAA GCATAAGCAG TGAATTGGAA AGTCTGAAGG TAAATCTTAA TATCTTTCTG 1800
TTGGGTGCAG CAGGAAGAAA AAACCTTCAG GATTTTGCTG CTTGTGGAAT AGACAGAATG 1860
AATTATGACA GCTACTTGGC TCAGACTGGT AAATCCCCCG CAβGAGTβAA TCTTTTATCA 1920
TTTGCATATG ATCTAGAAGC AAAAGCAAAC AGTTTGCCCC CAGGAAATTT GAGGAACTCC 1980
CTGAAAAGAG ATGCACAAAC TATTAAAACA ATTCACCAGC AACGAGTCCT TCCTATAGAA 2040
CAATCACTGA GCACTCTATA CCAAAGCGTC AAGATACTTC AACGCACAGG GAATGGATTβ 2100
TTGGAGAGAG TAACTAGGAT TCTAGCTTCT CTGGATTTTG CTCAGAACTT CATCACAAAC 2160
AATACTTCCT CTGTTATTAT TGAGGAAACT AAGAAGTATG GGAGAACAAT AATAGGATAT 2220
TTTCAACATT ATCTGCAGTG GATCGAGTTC TCTATCAGTG AGAAAGTGGC ATCGTGCAAA 2280
CCTGTβGCCA CCGCTCTAGA TACTGCTGTT GATGTCTTTC TGTGTAGCTA CATTATCGAC 2340
CCCTTGAATT TGTTTTGβTT TGGCATAGGA AAAGCTACTβ TATTTTTACT TCCGGCTCTA 2400
ATTTTTGCGG TAAAACTGGC TAAGTACTAT CGTCGAATGG ATTCGGAGGA CGTGTACGAT 2460
GATGTT6AAA CTATACCCAT GAAAAATATG GAAAATGGTA ATAATGGTTA TCATAAAGAT 2520
CATβTATATG GTATTCACAA TCCTGTTATG ACAAGCCCAT CACAACATTG A 2571
Seq ID NO : C41 DNA Sequence Nucleic Acid Accession #: NM_033049 Coding sequence: 28..1566
1 11 21 31 41 51 1 1 | 1 1 1 | 1 | 1 CCACGCGTCC GAGCAAGAAC AGCTAAAATG AAAGCCATCA TTCATCTTAC TCTTCTTGCT 60
CTCCTTTCTG TAAACACAGC CACCAACCAA GGCAACTCAG CTGATGCTGT AACAACCACA 120
GAAACTGCGA CTAGTGGTCC TACAGTAGCT GCAGCTGATA CCACTGAAAC TAATTTCCCT 180
GAAACTGCTA GCACCACAGC AAATACACCT TCTTTCCCAA CAGCTACTTC ACCTGCTCCC 240
CCCATAATTA GTACACATAG TTCCTCCACA ATTCCTACAC CTGCTCCCCC CATAATTAGT 300
ACACATAGTT CCTCCACAAT TCCTATACCT ACTGCTβCAG ACAGTβAGTC AACCACAAAT 360
GTAAATTCAT TAGCTACCTC TGACATAATC ACCGCTTCAT CTCCAAATGA TGGATTAATC 420
ACAATCGTTC CTTCTGAAAC ACAAAGTAAC AATβAAATGT CCCCCACCAC AGAAGACAAT 480
CAATCATCAG GGCCTCCCAC TGGCACCGCT TTATTGGAGA CCAGCACCCT AAACAGCACA 540
GGTCCCAGCA ATCCTTGCCA AGATGATCCC TGTGCAGATA ATTCGTTATG TGTTAAGCTG 600
CATAATACAA GTTTTTGCCT GTGTTTAGAA GGβTATTACT ACAACTCTTC TACATGTAAG 660
AAAGGAAAGG TATTCCCTGG GAAGATTTCA GTβACAGTAT CAGAAACATT TGACCCAGAA 720
GAGAAACATT CCATGGCCTA TCAAGACTTG CATAGTGAAA TTACTAGCTT GTTTAAAGAT 780
GTATTTGGCA CATCTGTTTA TGGACAGACT GTAATTCTTA CTGTAAGCAC ATCTCTGTCA 840
CCAAGATCTG AAATGCGTGC TGATGACAAG TTTGTTAATG TAACAATAGT AACAATTTTG 900
GCAβAAACCA CAAGTGACAA TGAGAAGACT GTGACTGAGA AAATTAATAA AGCAATTAGA 960
AβTAβCTCAA GCAACTTTCT AAACTATGAT TTGACCCTTC GGTβTGATTA TTATGGCTGT 1020
AACCAGACTG CGGATGACTG CCTCAATGGT TTAGCATGCG ATTGCAAATC TGACCTβCAA 1080
AGGCCTAACC CACAGAGCCC TTTCTGCGTT GCTTCCAGTC TCAAGTGTCC TβATβCCTGC 1140
AACGCACAGC ACAAGCAATG CTTAATAAAG AAGAGTGβTG GGGCCCCTGA GTGTGCGTGC 1200
GTGCCCGGCT ACCAGGAAGA TGCTAATGGG AACTGCCAAA AGTGTGCATT TGGCTACAGT 1260
GGACTCGACT GTAAGGACAA ATTTCAGCTG ATCCTCACTA TTGTGGGCAC CATCGCTGGC 1320
ATTGTCATTC TCAGCATGAT AATTGCATTβ ATTGTCACAG CAAGATCAAA TAACAAAACG 1380
AAGCATATTG AAGAAGAGAA CTTGATTGAC GAAGACTTTC AAAATCTAAA ACTGCCGTCG 1440
ACAGβCTTCA CCAATCTTGG AGCAGAAGGG AGCGTCTTTC CTAAGβTCAG GATAACGGCC 1500
TCCA6AGACA GCCAGATGCA AAATCCCTAT TCAAGACACA GCAGCATGCC CCGCCCTGAC 1560
TATTAGAATC ATAAGAATGT GGAACCCGCC ATGGCCCCCA ACCAATGTAC AAGCTATTAT 1620
TTAGAGTGTT TAGAAAGACT GATGβAGAAG TGAGCACCAG TAAAGATCTG βCCTCCGGGG 1680
TTTTTCTTCC ATCTGACATC TGCCAGCCTC TCTGAATGGA AGTTβTβAAT GTTTGCAACG 1740
AATCCAGCTC ACTTGCTAAA TAAGAATCTA TGACATTAAA TGTAβTAβAT GCTATTAGCG 1800
CTTGTCAGAG AββTGGTTTT CTTCAATCAG TACAAAGTAC TGAGACAATG GTTAGGGTTG 1860
TTTTCTTAAT TGTTTTCCTG GTAGGGCAAC AAGAACCATT TCCAATCTAβ AGGAAAGCTC 1920
CCCAGCATTG CTTGCTCCTG GGCAAACATT GCTCTTGAGT TAAβTβACCT AATTCCCCTG 1980
GGAGACATAC GCATCAACTG TGGAGGTCCG AGGGGATGAG AAGGβATACC CACCACCTTT 2040
CAAGGGTCAC AAGCTCACTC TCTGACAAGT CAGAATAGGG ACACTβCTTC TATCCCTCCA 2100
ATGGAGAGAT TCTGGCAACC TTTGAACAGC CCAGAGCTTG CAACCTA6CC TCACCCAAGA 2160
AGACTGGAAA GAGACATATC TCTCAGCTTT TTCAGGAGGC GTGCCTGGGA ATCCAGGAAC 2220
TTTTTGATGC TAATTAGAAG GCCTGGACTA AAAATGTCCA CTATGGGGTG CACTCTACAG 2280
TTTTTGAAAT GCTAGGAGGC AGAA6GGGCA GAGAGTAAAA AACATGACCT GGTAGAAGGA 2340
AGAGAGGCAA AGGAAACTGβ GTGGGGAGGA TCAATTAGAG AGGAGGCACC TGGGATCCAC 2400
CTTCTTCCTT AGGTCCCCTC CTCCATCAGC AAAGGAGCAC TTCTCTAATC ATGCCCTCCC 2460
GAAGACTGGC TGGGAGAAGG TTTAAAAACA AAAAATCCAG GAGTAAGAGC CTTAGGTCAG 2520
TTTGAAATTG GAGACAAACT GTCTGGCAAA GGGTGCGAGA GGGAGCTTGT GCTCAGGAGT 2580
CCAGCCGTCC AGCCTCGGGG TGTAGGTTTC TGAGβTGTβC CATTGGGGCC TCAGCCTTCT 2640
CTGβTGACAG AGGCTCAGCT βTGGCCACCA ACACACAACC ACACACACAC AACCACACAC 2700
ACAAATGGGG GCAACCACAT CCAGTACAAG CTTTTACAAA TGTTATTAGT GTCCTTTTTT 2760
ATTTCTAATG CCTTGTCCTC TTAAAAGTTA TTTTATTTGT TATTATTATT TGTTCTTGAC 2820
TGTTAATTGT GAATGGTAAT GCAATAAAGT GCCTTTGTTA GATGGTGAAA AAAAAAAAAA 2880
AAAAAAA 2887
Seq ID NO: C42 DNA Sequence
Nucleic Acid Accession ff: NM_001432.1
Coding sequence: 167..676
11 21 31 41 51
I I I I I
TCACTTGCCT GATATTTCCA GTGTCAGAGG GACACAGCCA ACGTGGGGTC CCTTCTAGGC 60 TGACAGCCGC TCTCCAGCCA CTGCCGCGAG CCCGTCTGCT CCCGCCCTGC CCGTGCACTC 120 TCCGCAGCCG CCCTCCGCCA AGCCCCAGCG CCCGCTCCCA TCGCCGATβA CCGCGGGGAG 180 GAGβATGGAG ATGCTCTGTG CCGGCAGGGT CCCTGCGCTG CTGCTCTGCC Tβ∞TTTCCA 240 TCTTCTACAG βCAGTCCTCA GTACAACTGT GATTCCATCA TGTATCCCAG GAGAGTCCAG 300 TGATAACTGC ACAGCTTTAG TTCAGACAGA AGACAATCCA CGTGTGGCTC AAGTβTCAAT 360 AACAAAGTGT AGCTCTGACA TGAATGGCTA TTGTTTGCAT GGACAGTGCA TCTATCTββT 420 GGACATGAGT CAAAACTACT GCAGGTGTGA AGTGGGTTAT ACTGGTGTCC GATβTβAACA 480 CTTCTTTTTA ACCGTCCACC AACCTTTAAG CAAAGAβTAT GTGGCTTTGA CCGTGATTCT 540 TATTATTTTG TTTCTTATCA CAGTCGTCGG TTCCACATAT TATTTCTGCA GATGGTACAG 600 AAATCGAAAA AGTAAAGAAC CAAAGAAGGA ATATGA6AGA GTTACCTCAG GGGATCCAGA 660 GTTGCCGCAA GTCTGAATAT GAβAβAGTTA CCTCAGGG6A TCCAGACTTG CCGCAAGTCT 720 GAATβGCGCC ATCAAACTTA TGGGCAGGGA TAACAGTβTG CCTGGTTAAT ATTAATATTC 780 CATTTTATTA ATAATATTTA TGTTGGGTCA AGTGTTAGGT CAATAACACT GTATTTTAAT 840 GTACTTGAAA AATGTTTTTA TTTTTGTTTT ATTTTTGACA GACTATTTGC TAATGTATAA 900 TGTGCAGAAA ATATTTAATA TCAAAAGAAA ATTGATATTT TTATACAAGT AATTTCCTGA 960 GCTAAATGCT TCATTGAAAG CTTCAAAGTT TATATGCCTG GTGCACAGTG CTTAGAAGTA 1020 AGCAATTCCC AGGTCATAGC TCAAGAATTG TTAGCAAATG ACAGATTTCT GTAAGCCTAT 1080 ATATATAGTC AAATCGATTT AGTAAGTATG TTTTTTATGT TCCTCAAATC AGTGATAATT 1140 GGTTTGACTG TACCATGGTT TGATATGTAG TTGGCACCAT GGTATCATAT ATTAAAACAA 1200 TAATGCAATT AGAATTTGGG AGAAGCAAAT ATAGβTCCTG TGTTAAACAC TACACATTTG 1260 AAACAAGCTA ACCCTGGGGA GTCTATGGTC TCTTCACTCA GGTCTCAGCT ATAATTCTGT 1320 TATATGAGGG GCAGTGGACA GTTCCCTATG CCAACTCACG ACTCCTACAG GTACTAGTCA 1380 CTCATCTACC AGATTCTGCC TATGTAAAAT GAATTGAAAA ACAATTTTCT GTAATCTTTT 1440
ATTTAAGTAG TGGGCATTTC ATAGCTTCAC AATGTTCCTT TTTTGTATAT TACAACATTT 1500
ATGTGAGGTA ATTATTGCTC AACAGACAAT TAGAAAAAAG TCCACACTTG AAGCCTAAAT 1560
TTβTGCTTTT TAAGAATATT TTTAGACTAT TTCTTTTTAT AGβGGCTTTG CTβAATTCTA 1620 ACATTAAATC ACAβCCCAAA ATTTGATGGA CTAATTATTA TTTTAAAATA TATGAAGACA 1680
ATAATTCTAC ATGTTGTCTT AAGATGGAAA TACAGTTATT TCATCTTTTA TTCAAGGAAG 1740
TTTTAACTTT AATACAGCTC AGTAAATGGC TTCTTCTAGA ATGTAAAGTT ATGTATTTAA 1800
AGTTGTATCT TGACACAGGA AATGGGAAAA AACTTAAAAA TTAATATGGT βTATTTTTCC 1860
AAATGAAAAA TCTCAATTGA AAGCTTTTAA AATGTAGAAA CTTAAACACA CCTTCCTGTG 1920 GAGGCTGAGA TGAAAACTAG GGCTCATTTT CCTGACATTT GTTTATTTTT TGGAAGAGAC 1980
AAAGATTTCT TCTβCACTCT GAGCCCATAG GTCTCAGAGA GTTAATAGGA GTATTTTTGG 2040
GCTATTGCAT AAGGAGCCAC TGCTGCCACC ACTTTTGGAT TTTATGGGAG GCTCCTTCAT 2100
CGAATGCTAA ACCTTTGAGT AGAGTCTCCC TGGATCACAT ACCAGGTCAG GGAGGATCTG 2160
TTCTTCCTCT ACGTTTATCC TGGCATβTβC TAGGGTAAAC βAAeβCATAA TAAGCCATGβ 2220 CTGACCTCTG GAGCACCAGG TGCCAGGACT TGTCTCCATG TGTATCCATβ CATTATATAC 2280
CCTGGTGCAA TCACACGACT βTCATCTAAA GTCCTGGCCC TGGCCCTTAC TATTAGGAAA 2340
ATAAACAGAC AAAAACAAGT AAATATATAT GGTCCTATAC ATATTGTATA TATATTCATA 2400
TACAAACATG TATGTATACA TGACCTTAAT GGATCATAGA ATTGCAGTCA TTTGGTGCTC 2460
TGCTAACCAT TTATATAAAA CTTAAAAACA AGAGAAAAGA AAAATCAATT AGATCTAAAC 2520 AGTTATTTCT GTTTCCTATT TAATATAGCT GAAGTCAAAA TATGTAAGAA CACATTTTAA 2580
ATACTCTACT TACAGTTGGC CCTCTGTGGT TAGTTCCACA TCTGTGβATT CAACCAACCA 2640
AGGACGGAAA ATGCTTAAAA AATAATACAA CAACAACAAA AAATACATTA TAACAACTAT 2700
TTACTTTTTT TTTTTTCTTT TTGAGATGGA GTCTCGCTCT GTTGCCCAGG TTGGAGTGCA 2760
GTGGCACGAT CTCGGCTCAC TGCAACCTCA CCTCCCGGGT TCAAGAGATC CTCCTGCCTC 2820 AGCCTCCTCA βCAGCTGGGA CTACAGGCGC ATGCCACCAT GCCCAGCTAA TTTTTGTATT 2880
TTTAGTAGAG GCGGGGTTTC ACCATGTTGG CCAGGATGGT CTCAATCTCC TAACCTTGAG 2940
ATCCACCCTC CACAGCCTCC CAAACTGCTG GβATTACAGG CGTβAβCCAC CGCACβTAβC 3000
ATTTACATTA GCTATTACAA GTAATGTAAA βATβATTTAA GTATACAGGA GGATGTGAAT 3060
AGGTTATATG CAAGCACTAT GCCCTTTTAT ATAAGTGACT TGAACATCTG TGCCCGATTT 3120 TAGTATGTGC AGGGGGGCGA TCTGGGAATC AGTCCCCTGT GGATACCAAG GTACAACTGT 3180
ATTTATTAAC GCTTACTAGA TGTGAGβAGA GTCTGAATAT TTTCAGTGAT CTTGGCTGTT 3240
TCAAAAAAAT CTATTGACTT TTCAATAAAT CAGCTGCAAT CCATTTATTT CATTTACAAA 3300
AGATTTATTG TAAGCCTCTC AATCTTGGTT TTTCAGTTGA TCTTAAGCAT GTCAATTCAT 3360
AAAAACAAGT CATTTTTGTA TTTTTCATCT TTAAGAATGC TTAAAAAAGC TAATCCCTAA 3420 AATAGTTAGA TCTTTGTAAA TGCATATTAA ATAATAAAGT ATGACCCAGA TTACTTTTTA 3480
TGGGTGAAAA TAAGACAAAA ATAATAGTTT TAβTGAβGAT GGTGCTGAGT AAACATAAAA 3540
ACTGATTTGC TCTCAβCTGA TGTGTCCTGT ACACAGTGGG AAGATTTTAβ TTCACACTTA 3600
GTCTAACTCC CCCATTTTAC AGATTTCTCA CTATATATAT TTCTAGAAGβ GGCTATGCAT 3660
ATTCAATGTA TTβAβAACCA AAβCAACCAC AAATGCATAA ATGCATAATT TATβGTCTTC 3720 AACCAAGβCC ACATAATAAC CCAGTTAACT TACTCTTTAA CCAGGAATAT TAAGTTCTAT 3780
AACTAGTACT CAAGβTTTAA CCTTAAAATT AAGATTTCCT TAACCTTAAC CTTAAAATTG 3840
ATATTATATT AAACATACAT AATACAATGT AACTCCACTG TTCTCCTGAA TATTTTTTGC 3900
TCTAATCTCT CTGCCGAAAG TCAAAGTGAT GGβAGAATTG GTATACTGGT ATGACTACCT 3960
CTTAAβTCAG ATTTTTATTT ATGAGTCTTT GAGACTAAAT TCAATCACCA CCAGGTATCA 4020 AATCAACTTT TATGCAGCAA ATATATGATT CTAGTGTCTG ACTTTTGTTA AATTCAGTAA 4080
TGCAGTTTTT AAAAACCTGT ATCTGACCCA CTTTGTAATT TTTGCTCCAA TATCCATTCT 4140
GTAGACTTTT GAAAAAAAAG TTTTTAATTT GATGCCCAAT ATATTCTGAC CGTTAAAAAA 4200
TTCTTGTTCA TATGGGAGAA GGGGGAGTAA TGACTTGTAC AAACAGTATT TCTGGTGTAT 4260
ATTTTAATGT TTTTAAAAAG AGTAATTTCA TTTAAATATC TGTTATTCAA ATTTGATGAT 4320 GTTAAATβTA ATATAATGTA fTTTCTTTTT ATTTTGCACT CTGTAATTGC ACTTTTTAAG 4380
TTTGAAGAGC CATTTTGGTA AACGGTTTTT ATTAAAGATG CTATGGAACA TAAAGTTGTA 4440
TTGCATGCAA TTTAAAGTAA CTTATTTGAC TATGAATATT ATCGGATTAC TGAATTGTAT 4500
CAATTTGTTT GTGTTCAATA TCAGCTTTGA TAATTGTGTA CCTTAAGATA TTGAAGGAGA 4560
AAATAGATAA TTTACAAGAT ATTATTAATT TTTATTTATT TTTCTTGGGA ATTGAAAAAA 4620 ATTβAAATAA ATAAAAATGC ATTGAACATC TTGCATTCAA AATCTTCACT GAC 4673
Seq ID NO: C43 DNA Sequence
Nucleic Acid Accession ft: AF011468.1
Coding sequence: 257..1468
1 11 21 31 41 51 1 1 1 I 1 | 1 | 1 | 1 GGAAGACTTG GGTCCTTGGG TCGCAGGTGG GAGCCGACGG GTGGβTAGAC CGTGGGβGAT 60
ATCTCAGTGG CGGACGAGGA CGGCGGGGAC AAGGGGCGGC TGGTCGβAGT GGCGβAGCCT 120
CAAGTCCCCT GTCGGTTCCT GCGTCCCTGA GTGTCCTTGG CGCTGCCTTG TGCCCGCCCA 180
GCGCCTTTGC ATCCGCTCCT GGGCACCGAG GCGCCCTGTA GGATACTGCT TGTTACTTAT 240
TACAGCTAGA GGCATCATGG ACCGATCTAA AGAAAACTGC ATTTCAGGAC CTGTTAAGGC 300
TACAGCTCCA GTTGGAGGTC CAAAACGTGT TCTCGTGACT CAGCAAATTC CTTGTCAGAA 360
TCCATTACCT GTAAATAGTG GCCAGGCTCA GCGGGTCTTG TGTCCTTCAA ATTCTTCCCA 420
GCGCGTTCCT TTGCAAGCAC AAAAGCTTGT CTCCAGTCAC AAGCCGGTTC AGAATCAGAA 480
GCAGAAGCAA TTGCAGGCAA CCAGTGTACC TCATCCTGTC TCCAGGCCAC TGAATAACAC 540
CCAAAAGAGC AAGCAGCCCC TGCCATCGGC ACCTGAAAAT AATCCTGAGG AGGAACTGGC 600
ATCAAAACAG AAAAATGAAG AATCAAAAAA GAGGCAGTGG eCTTTGGAAG ACTTTGAAAT 660
TGGTCGCCCT CTGGGTAAAG GAAAGTTTGG TAATGTTTAT TTGGCAAGAG AAAAGCAAAG 720
CAAGTTTATT CTGGCTCTTA AAGTGTTATT TAAAGCTCAG CTGGAGAAAG CCGGAGTGGA 780
GCATCAGCTC AGAAGAGAAG TAGAAATACA GTCCCACCTT CGGCATCCTA ATATTCTTAG 840
ACTGTATGGT TATTTCCATG ATGCTACCAG AGTCTACCTA ATTCTGGAAT ATGCACCACT 900
TGGAACAGTT TATAGAGAAC TTCAGAAACT TTCAAAGTTT GATGAGCAGA GAACTGCTAC 960
TTATATAACA GAATTQ3CAA ATGCCCTGTC TTACTGTCAT TCGAAβAGAG TTATTCATAG 1020
ACACATTAAG CCAGAGAACT TACTTCTTGG ATCACCTGGA GAGCTTAAAA TTGCAGATTT 1080
TGGGTGβTCA GTACATβCTC CATCTTCCAG GAGGACCACT CTCTGTGGCA CCCTGGACTA 1140
CCTGCCCCCT GAAATGATTG AAGGTCGGAT βCATGATGAG AAGGTGGATC TCTGGAβCCT 1200
TGGAGTTCTT TGCTATGAAT TTTTAGTTGG GAAGCCTCCT TTTGAGGCAA ACACATACCA 1260 AGAGACCTAC AAAAβAATAT CACGGGTTGA ATTCACATTC CCTGACTTTβ TAACAGAGGG 1320
AGCCAGGGAC CTCATTTCAA GACTGTTGAA GCATAATCCC AGCCAGAGGC CAATGCTCAG 1380
AGAAGTACTT GAACACCCCT GβATCACAGC AAATTCATCA AAACCATCAA ATTGCCAAAA 1440
CAAAGAATCA GCTAGCAAAC AGTCTTAGGA ATCGTGCAGG GGGAGAAATC CTTGAGCCAG 1500
GGCTGCCATA TAACCTGACA G6AACATGCT ACTGAAGTTT ATTTTACCAT TGACTβCTGC 1560
CCTCAATCTA GAACGCTACA CAAGAAATAT TTGTTTTACT CAGCAGGTGT GCCTTAACCT 1620
CCCTATTCAG AAAGCTCCAC ATCAATAAAC ATGACACTCT GAAGTGAAAG TAGCCACGAG 1680
AATTGTGCTA CTTATACTGG TTCATAATCT GGAGGCAAGG TTCGACTGCA GCCGCCCCGT 1740
CAGCCTGTGC TAGGCATGGT GTCTTCACAG GAGGCAAATC CAGAGCCTGG CTGTGGGGAA 1800
AGTGACCACT CTGCCCTGAC CCCGATCAGT TAAGGAGCTG TGCAATAACC TTCCTAGTAC 1860
CTGAGTGAGT GTGTAACTTA TTGββTTβGC GAAGCCTGGT AAAGCTGTTG GAATGAGTAT 1920
GTGATTCTTT TTAAGTATGA AAATAAAGAT ATATGTACAG ACTTGTATTT TTTCTCTGGT 1980
GGCATTCCTT TAGGAATGCT GTGTGTGTGT CCGGCACCCC GGTAGβCCTG ATTGGGTTTC 2040
TAGTCCTCCT TAACCACTTA TCTCCCATAT GAGAGTGTβA AAAATAGGAA CACGTGCTCT 2100
ACCTCCATTT AGGGATTTGC TTGGGATACA GAAGAGGCCA TGTGTCTCAG AGCTGTTAAG 2160
GGCTTATTTT TTTAAAACAT TGGAGTCATA GCATGTGTGT AAACTTTAAA TATGCAAATA 2220
AATAAGTATC TATGTCTAAA AAAAAAAAAA AAA 2253
Seq ID NO: C44 DNA Sequence Nucleic Acid Accession ft: NM__013372 Coding sequence: 63..617
1 11 21 31 41 51
I I 1 I I I
GCGGCCGCAC TCAGCGCCAC GCGTCβAAAG CGCAGGCCCC GAGGACCCGC CGCACTGACA 60
GTATGAGCCG CACAGCCTAC ACGGTβGGAG CCCTGCTTCT CCTCTTGGGG ACCCTGCTGC 120
CGGCTGCTGA AGGGAAAAAG AAAGGGTCCC AAGGTGCCAT CCCCCCGCCA GACAAGGCCC 180
AGCACAATGA CTCAGAGCAG ACTCAGTCGC CCCAGCAGCC TGGCTCCAGG AACCGGGGGC 240 βGGGCCAAGG GCGGGGCACT GCCATGCCCG GGGAGGAGGT GCTGGAGTCC AGCCAAGAGG 300
CCCTGCATGT GACGGAGCGC AAATACCTGA AGCGAGACTG GTGCAAAACC CAGCCGCTTA 360
AGCAGACCAT CCACGAGGAA GGCTGCAACA GTCGCACCAT CATCAACCGC TTCTGTTACG 420
GCCAGTGCAA CTCTTTCTAC ATCCCCAGGC ACATCCGGAA GGAGGAAGGT TCCTTTCAGT 480
CCTGCTCCTT CT6CAAGCCC AAGAAATTCA CTACCATGAT GGTCACACTC AACTGCCCTG 540
AACTACAGCC ACCTACCAAG AAGAAGAβAβ TCACACGTGT GAAGCAGTβT CGTTGCATAT 600
CCATCGATTT GGATTAAGCC AAATCCAGGT GCACCCAGCA TGTCCTAGGA ATGCAGCCCC 660
AGGAAGTCCC AGACCTAAAA CAACCAGATT CTTACTTGGC TTAAACCTAβ AGGCCAGAAβ 720
AACCCCCAGC TGCCTCCTGβ CAGGAGCCTG CTTGTGCGTA GTTCGTGTGC ATGAGTGTGG 780
ATGGGTGCCT GTGββTβTTT TTAGACACCA GAGAAAACAC AGTCTCTGCT AGAGAGCACT 840
CCCTATTTTG TAAACATATC TGCTTTAATG GGGATGTACC AGAAACCCAC CTCACCCCGG 900
CTCACATCTA AAGG6GCGGG GCCGTGGTCT GGTTCTGACT TTGTGTTTTT GTGCCCTCCT 960
GGGGACCAGA ATCTCCTTTC GGAATGAATG TTCATGGAAG AGGCTCCTCT GAGβGCAAGA 1020
GACCTGTTTT AβTGCTGCAT TCGACATGGA AAAGTCCTTT TAACCTβTGC TTGCATCCTC 1080
CTTTCCTCCT CCTCCTCACA ATCCATCTCT TCTTAAGTTG ATAGTGACTA TGTCAGTCTA 1140
ATCTCTTGTT TβCCAAGGTT CCTAAATTAA TTCACTTAAC CATGATGCAA ATGTTTTTCA 1200
TTTTGTGAAG ACCCTCCAGA CTCTGGGAGA GGCTGGTGTG GGCAAGGACA AGCAGGATAG 1260
TGGAβTGAGA AAGGGAGGGT GGAGGGTGAG GCCAAATCAβ GTCCAGCAAA AGTCAGTAGG 1320
GAGATTGGAG AAGCTTGAAA GGCCAATACC AGAACACAββ CTGATGCTTC TGAGAAAGTC 1380
TTTTCCTAGT ATTTAACAGA ACCCAAGTGA ACAGAGGAGA AATGAGATTG CCAGAAAGTG 1440
ATTAACTTTG GCCGTTGCAA TCTβCTCAAA CCTAACACCA AACTGAAAAC ATAAATACTG 1500
ACCACTCCTA TGTTCGGACC CAAGCAAGTT AGCTAAACCA AACCAACTCC TCTGCTTTGT 1560
CCCTCAGGTG GAAAAGAGAG GTAGTTTAGA ACTCTCTGCA TAGβββTGGG AATTAATCAA 1620
AAACCKCAGA GGCTβAAATT CCTAATACCT TTCCTTTATC GTG6TTATAG TCAGCTCATT 1680
TCCATTCCAC TATTTCCCAT AATGCTTCTG AGAGCCACTA ACTTGATTGA TAAAGATCCT 1740
GCCTCTGCTG AGTGTACCTβ ACAGTAAGTC TAAAGATGAR AGAGTTTAGG GACTACTCTG 1800
TTTTAGCAAG ARATATTKTβ GββGTCTTTT TGTTTTAACT ATTGTCAGGA GATTGGGCTA 1860
RAGAGAAGAC GACGAGAGTA AβGAAATAAA GGGRATTGCC TCTGGCTAGA GAGTAAGTTA 1920 ββTGTTAATA CCTGGTAGAA ATGTAAGGGA TATGACCTCC CTTTCTTTAT GTGCTCACTG 1980
AGGATCTGAG GGGACCCTGT TAGGAGAβCA TAGCATCATG ATGTATTAGC TGTTCATCTG 2040
CTACTGGTTG GATGGACATA ACTATTGTAA CTATTCAGTA TTTACTGGTA GGCACTGTCC 2100
TCTGATTAAA CTTGGCCTAC TGGCAATGGC TACTTAGGAT TGATCTAAGG GCCAAAGTGC 2160
AGGGTGGGTG AACTTTATTG TACTTTGGAT TTGGTTAACC TGTTTTCTTC AAGCCTGAGG 2220
TTTTATATAC AAACTCCCTG AATACTCTTT TTGCCTTGTA TCTTCTCAGC CTCCTAGCCA 2280
AGTCCTATGT AATATGGAAA ACAAACACTG CAGACTTGAG ATTCAGTTGC CGATCAAGGC 2340
TCTGGCATTC AGAGAACCCT TGCAACTCGA GAAGCTβTTT TTATTTCGTT TTTGTTTTGA 2400
TCCAGTGCTC TCCCATCTAA CAACTAAACA GGAGCCATTT CAAGGCGGGA GATATTTTAA 2460
ACACCCAAAA TGTTGGGTCT GATTTTCAAA CTTTTAAACT CACTACTGAT GATTCTCACG 2520
CTAGGCGAAT TTGTCCAAAC ACATAGTGTG TGTGTTTTGT ATACACTGTA TβACCCCACC 2580
CCAAATCTTT GTATTGTCCA CATTCTCCAA CAATAAAGCA CAGAGTG6AT TTAATTAAGC 2640
ACACAAATGC TAAGGCAGAA TTTTGAGGGT GGGAGAGAAG AAAAGQ3AAA GAAGCTGAAA 2700
ATGTAAAACC ACACCAGGGA GGAAAAATGA CATTCAGAAC CAGCAAACAC TGAATTTCTC 2760
TTGTTGTTTT AACTCTGCCA CAAGAATGCA ATTTCGTTAA TGGAGATGAC TTAAGTTGGC 2820
AGCAGTAATC TTCTTTTAGG AβCTTGTACC ACAGTCTTGC ACATAAGTGC AGATTTGβCT 2880
CAAGTAAAGA GAATTTCCTC AACACTAACT TCACTGGβAT AATCAGCAGC GTAACTACCC 2940
TAAAAβCATA TCACTAGCCA AAGAGGGAAA TATCTGTTCT TCTTACTGTG CCTATATTAA 3000
GACTAGTACA AATβTβGTGT GTCTTCCAAC TTTCATTβAA AATGCCATAT CTATACCATA 3060
TTTTATTCGA GTCACTGATG ATGTAATGAT ATATTTTTTC ATTATTATAG TAGAATATTT 3120
TTATGGCAAG ATATTTGTGG TCTTGATCAT ACCTATTAAA ATAATGCCAA ACACCAAATA 3180
TGAATTTTAT GATGTACACT TTGTGCTTGG CATTAAAAGA AAAAAACACA CATCCTGGAA 3240
GTCTGTAAGT TGTTTTTTGT TACTGTAGGT CTTCAAAGTT AAGAGTGTAA GTGAAAAATC 3300
TGGAGGAGAβ GATAATTTCC ACTGTGTGGA ATGTGAATAG TTAAATGAAA AβTTATGGTT 3360
ATTTAATGTA ATTATTACTT CAAATCCTTT GGTCACTGTG ATTTCAAGCA TGTTTTCTTT 3420
TTCTCCTTTA TATGACTTTC TCTGAGTTGG GCAAAGAAGA AGCTGACACA CCGTATGTTG 3480
TTAGAGTCTT TTATCTGGTC AGββGAAACA AAATCTTGAC CCAGCTGAAC ATGTCTTCCT 3540 βAβTCAGTGC CTGAATCTTT ATTTTTTAAA TTGAATGTTC CTTAAAGGTT AACATTTCTA 3600 AAGCAATATT AAGAAAGACT TTAAATβTTA TTTTGGAAGA CTTACGATGC ATGTATACAA 3660
ACGAATAGCA GATAATGATG ACTAGTTCAC ACATAAAGTC CTTTTAAGGA GAAAATCTAA 3720
AATGAAAAGT GGATAAACAG AACATTTATA AGTGATCAGT TAATGCCTAA GAGTβAAAGT 3780
AGTTCTATTG ACATTCCTCA AGATATTTAA TATCAACTGC ATTATGTATT ATGTCTGCTT 3840
AAATCATTTA AAAACGGCAA AGAATTATAT AGACTATGAG GTACCTTGCT GTGTAGGAGG 3900
ATGAAAGGGG AGTTGATAGT CTCATAAAAC TAATTTGGCT TCAAGTTTCA TGAATCTGTA 3960
ACTAGAATTT AATTTTCACC CCAATAATGT TCTATATAGC CTTTGCTAAA GAGCAACTAA 4020
TAAATTAAAC CTATTCTTTC AAAAAAAAA 4049 Seq ID NO: C45 DNA Sequence
Nucleic Acid Accession ft: Eos sequence Coding sequence: 200..2932
1 11 21 31 41 51
I I I I I
ATTGCTGATG GATCAGTGAG CCTGTβTTCA TGCCAβTGAG CTGCTβTGGC TCAGATACTG 60 ATACTTTCTT TCCAAACAGC ATAAGAA6TG ATTGA6CCAC AAGTATACTG AAGβAAeeGC 120 TCCCTCGAGT TCTGGTGTGA AGAGATAAAT CACCAGTCAC AGACTATGCA CCCGACTβCT 180 GCTGTTCAGT CCAGGGAAAA TGAAAGTTββ AGTGCTGTβG CTCATTTCTT TCTTCACCTT 240 CACTGACGGC CACGGTGGCT TCCTGGGGAA AAATGATGGC ATCAAAACAA AAAAAGAACT 300 CATTGTGAAT AAGAAAAAAC ATCTAGGCCC AGTCGAAGAA TATCAGCTGC TGCTTCAGGT 360 GACCTATAGA GATTCCAAGG AGAAAAGA6A TTTGAGAAAT TTTCTGAAGC TCTTGAAGCC 420 TCCATTATTA TGGTCACATG ββCTAATTAβ AATTATCAGA 6CAAAGGCTA CCACAβACTβ 480 CAACAGCCTG AATGGAGTCC TβCAβTGTAC CTGTGAAGAC AGCTACACCT GGTTTCCTCC 540 CTCATGCCTT GATCCCCAGA ACTGCTACCT TCACACGGCT GGAGCACTCC CAAGCTGTGA 600 ATGTCATCTC AACAACCTCA GCCAGAGTGT CAATTTCTGT GAGAGAACAA AGATTTGGGG 660 CACTTTCAAA ATTAATGAAA GGTTTACAAA TGACCTTTTG AATTCATCTT CTGCTATATA 720 CTCCAAATAT GCAAATGGAA TTGAAATTCA ACTTAAAAAA GCATATGAAA GAATTCAAGG 780 TTTTGAGTCG GTTCAGGTCA CCCAATTTCG AAATGGAAGC ATCβTTβCTβ GGTATGAAGT 840 TGTTGGCTCC AGCAGTGCAT CTGAACTGCT GTCAGCCATT GAACATGTTβ CCGAGAAGGC 900 TAAGACAGCC CTTCACAAGC TGTTTCCATT AGAAGACββC TCTTTCAGAG TGTTCGGAAA 960 AGCCCAGTGT AATGACATTβ TCTTTGGATT TβGGTCCAAG GATGATGAAT ATACCCTGCC 1020 CTGCAGCAGT βGCTACAGGG GAAACATCAC AGCCAAGTGT GAGTCCTCTG GGTGGCAGGT 1080 CATCAGGGAβ ACTTGTGTGC TCTCTCTGCT TGAAGAACTG AACAAGAATT TCAGTATGAT 1140 TGTAGGCAAT GCCACTGAGG CAGCTGTGTC ATCCTTCGTG CAAAATCTTT CTGTCATCAT 1200 TCGGCAAAAC CCATCAACCA CAGTGGGGAA TCTGGCTTCG GTGGTGTCGA TTCTGAGCAA 1260 TATTTCATCT CTGTCACTGG CCAGCCATTT CAGGGTGTCC AATTCAACAA TGGAGGATGT 1320 CATCAGTATA GCTGACAATA TCCTTAATTC AGCCTCAGTA ACCAACTGGA CAGTCTTACT 1380 GCGGGAAGAA AAGTATGCCA GCTCACGGTT ACTAGAGACA TTAGAAAACA TCAGCACTCT 1440 GGTGCCTCCG ACAGCTCTTC CTCTGAATTT TTCTCGGAAA TTCATTGACT GGAAAGGGAT 1500 TCCAGTGAAC AAAAGCCAAC TCAAAAGGGG TTACAGCTAT CAGATTAAAA TGTGTCCCCA 1560 AAATACATCT ATTCCCATCA GAGGCCGTGT GTTAATTGGG TCAGACCAAT TCCAGAβATC 1620 CCTTCCAGAA ACTATTATCA GCATGGCCTC GTTGACTCTG GGGAACATTC TACCCβTTTC 1680 CAAAAATGβA AATGCTCAGG TCAATGGACC TGTGATATCC ACGGTTATTC AAAACTATTC 1740 CATAAATGAA GTTTTCCTAT TTTTTTCCAA GATAGAGTCA AACCTGAGCC AGCCTCATTG 1800 TGTGTTTTGG GATTTCAGTC ATTTGCAGTG GAACGATGCA GGCTGCCACC TAGTGAATGA 1860 AACTCAAGAC ATCGTGACGT βCCAATCTAC TCACTTGACC TCCTTCTCCA TATTGATGTC 1920 ACCTTTTGTC CCCTCTACAA TCTTCCCCCT TGTAAAATGβ ATCACCTATG TGGGACTGGG 1980 TATCTCCATT GGAAGTCTCA TTTTATGCCT GATCATCβAG GCTTTGTTTT βGAAGCAGAT 2040 TAAAAAAAGC CAAACCTCTC ACACACGTCG TATTTGCATG GTGAACATAG CCCTβTCCCT 2100 CTTGATTGCT GATGTCTGGT TTATTGTTGβ TGCCACAGTG GACACCACGG TGAACCCTTC 2160 TGGAGTCTGC ACAGCTGCTG TGTTCTTTAC ACACTTCTTC TACCTCTCTT TGTTCTTCTG 2220 GATGCTCATG CTTβGCATCC TGCTGGCTTA CCGGATCATC CTCGTGTTCC ATCACATGGC 2280 CCAGCATTTG ATGATGGCTG TTGGATTTTG CCTGGGTTAT GGGTGCCCTC TCATTATATC 2340 TGTCATTACC ATTGCTGTCA CGCAACCTAG CAATACCTAC AAAAGGAAAG ATGTGTGTTG 2400 GCTTAACTGG TCCAATGGAA GCAAACCACT CCTGGCTTTT GTTGTCCCTG CACTGGCTAT 2460 TGTGGCTGTG AACTTCGTTG TGGTGCTGCT AGTTCTCACA AAGCTCTGGA GGCCβACTGT 2520 TGGGGAAAGA CTGAGTCGGG ATGACAAGGC CACCATCATC CGCGTGGGGA AGAGCCTCCT 2580 CATTCTGACC CCTCTGCTAG GGCTCACCTG GGGCTTTGGA ATAGGAACAA TAGTGGACAG 2640 CCAGAATCTG GCTTGGCATG TTATTTTTGC TTTACTCAAT GCATTCCAGG GATTTTTTAT 2700 CTTATGCTTT GGAATACTCT TββACAβTAA GCTGCGACAA CTTCTGTTCA ACAAGTTβTC 2760 TGCCTTAAGT TCTTGGAAGC AAACAβAAAA βCAAAACTCA TCAGATTTAT CTGCCAAACC 2820 CAAATTCTCA AAGCCTTTCA ACCCACTβCA AAACAAAβGC CATTATGCAT TTTCTCATAC 2880 TGGAGATTCC TCCGACAACA TCATGCTAAC TCAGTTTGTC TCAAATGAAT AAββCAAGGA 2940 ATCATAAAAT CAAGAAAAAA TTTCCAGAAC AACTTGACAT TTAGAGACAA ATGTCAATGA 3000 AGAAATTATG CTCAGTATTC GATCGGGTTT TCTGATTTAG GGGTCTGGGA ATAAAACAAG 3060 AATGTCTCAG TGGCTTCA 3078
Seq ID NO: C46 DNA Sequence Nucleic Acid Accession ft: NM_000584.1
Coding sequence: 75..374
11 21 31 41 51
I I I I I
AGCAGAGCAC ACAAGCTTCT AGGACAAGAG CCAGGAAGAA ACCACCGGAA GGAACCATCT 60 CACTGTβTGT AAACATGACT TCCAAGCTGG CCGTGGCTCT CTTGGCAGCC TTCCTGATTT 120 CTGCAGCTCT GTGTGAAGGT GCAGTTTTGC CAAGGAGTGC TAAAGAACTT AGATGTCAGT 180 GCATAAAGAC ATACTCCAAA CCTTTCCACC CCAAATTTAT CAAAGAACTG AGAGTGATTG 240 AGAGTGGACC ACACTGCGCC AACACAβAAA TTATTGTAAA GCTTTCTGAT GGAAGAGAGC 300 TCTGTCTGGA CCCCAAGGAA AACTGGGTGC AGAGGGTTβT GGAGAAGTTT TTGAAGAGGG 360 CTGAGAATTC ATAAAAAAAT TCATTCTCTG TGGTATCCAA GAATCAGTGA AGATGCCAGT 420 GAAACTTCAA GCAAATCTAC TTCAACACTT CATGTATTGT GTGGGTCTGT TGTAGGGTTG 480 CCAGATGCAA TACAAGATTC CTGGTTAAAT TTGAATTTCA GTAAACAATG AATAGTTTTT 540 CATTGTACCA TGAAATATCC AGAACATACT TATATGTAAA GTATTATTTA TTTGAATCTA 600 CAAAAAACAA CAAATAATTT TTAAATATAA GGATTTTCCT AGATATTGCA CGGGAGAATA 660
TACAAATAGC AAAATTGAGC CAAGGGCCAA GAGAATATCC GAACTTTAAT TTCAGGAATT 720 βAATGGGTTT GCTAGAATGT GATATTTGAA GCATCACATA AAAATGATGG GACAATAAAT 780
TTTGCCATAA AGTCAAATTT AGCTGβAAAT CCTGGATTTT TTTCTGTTAA ATCTGGCAAC 840
CCTAGTCTGC TAGCCAGGAT CCACAAβTCC TTGTTCCACT GTGCCTTGGT TTCTCCTTTA 900
TTTCTAAGTβ GAAAAAGTAT TACCCACCAT CTTACCTCAC AGTGATGTTG TβAGGACATG 960
TGGAAGCACT TTAAGTTTTT TCATCATAAC ATAAATTATT TTCAAGTGTA ACTTATTAAC 1020
CTATTTATTA TTTATGTATT TATTTAAβCA TCAAATATTT GTGCAAGAAT TTGGAAAAAT 1080
AGAAGATGAA TCATTGATTG AATAβTTATA AAGATβTTAT AGTAAATTTA TTTTATTTTA 1140
GATATTAAAT GATGTTTTAT TAβATAAATT TCAATCAβGG TTTTTAGATT AAACAAAGAA 1200
ACAATTGGGT ACCCAGTTAA ATTTTCATTT CAGATAAACA ACAAATAATT TTTTAGTATA 1260
AGTACATTAT TGTTTATCTG AAAGTTTTAA TTGAACTAAC AATCCTAGTT TGATACTCCC 1320
AGTCTTGTCA TTGCCAGCTG TGTTGGTAGT GCTGTGTTGA ATTACGGAAT AATGAGTTAG 1380
AACTATTAAA ACAGCCAAAA CTCCACAGTC AATATTAGTA ATTTCTTGCT GGTTGAAACT 1440
TGTTTATTAT GTACAAATAG ATTCTTATAA TATTATTTAA ATGACTGCAT TTTTAAATAC 1500
AAGGCTTTAT ATTTTTAACT TTAAGATGTT TTTATGTGCT CTCCAAATTT TTTTTACTGT 1560
TTCTGATTGT ATGGAAATAT AAAAGTAAAT ATGAAACATT TAAAATATAA TTTGTTGTCA 1620
AAGTAAAAAA AAAAAAAAA 1639
Seq ID NO: C47 DNA Sequence
Nucleic Acid Accession ft: NM_005603.1
Coding sequence: 1..3756
21 31 41 51
A ITGAGTACAG AIAAGAGACTC AIGAAACGACA TITTGACGAGG AITTCTCAGCC TIAATGACGAA 60 GTGGTTCCCT ACAGTGATGA TGAAACAGAA GATGAACTTG ATGACCAGβG GTCTGCTGTT 120 GAACCAGAAC AAAACCGAGT CAACAGGGAA GCAGAββAGA ACCGGGAGCC ATTCAGAAAA 180 GAATGTACAT GGCAAGTCAA AGCAAACGAT CGCAAGTACC ACGAACAACC TCACTTTATG 240 AACACAAAAT TCTTGTGTAT TAAGGAGAGT AAATATGCβA ATAAT6CAAT TAAAACATAC 300 AAGTACAACβ CATTTACCTT TATACCAATG AATCTGTTTG AGCAGTTTAA GAGAGCAGCC 360 AATTTATATT TCCTGGCTCT TCTTATCTTA CAGGCAGTTC CTCAAATCTC TACCCTGGCT 420 TGGTACACCA CACTAGTGCC CGTGGTTGTG GTGCTGGGCG TCACTGCAAT CAAACACCTG 480 GTGGACGATG TGGCTCβCCA TAAAATGGAT AAGGAAATCA ACAATACGAC GTGTGAAGTC 540 ATTAAGGATG GCAGGTTCAA AGTTGCTAAG TGβAAAGAAA TTCAAGTTGG AGACGTCATT 600 CGTCTGAAAA AAAATGATTT TGTTCCAGCT GACATTCTCC TGCTGTCTAG CTCTGAGCCT 660 AACAGCCTCT GCTATGTGGA AACAGCAGAA CTGGACGGAG AAACCAATTT AAAATTTAAG 720 ATGTCACTTG AAATCACAGA CCAGTACCTC CAAAGAGAAG ATACATTGGC TACATTTGAT 780 GGTTTTATTG AATCTβAAGA ACCCAATAAC CGACTAGATA AGTTTACAGG AACACTATTT 840 TGGAGAAACA CAAGTTTTCC TTTGGATGCT GATAAAATTT TGTTACGTGG CTGTβTAATT 900 AGGAACACCG ATTTCTGCCA CGGCTTAGTC ATTTTTGCAG GTGCTGACAC TAAAATAATG 960 AAGAATAGTG GGAAAACCAG ATTTAAAAGA ACTAAAATTG ATTACTTGAT GAACTACATG 1020 GTTTACACGA TCTTTGTTGT TCTTATTCTG CTTTCTGCTG GTCTTGCCAT CGGCCATGCT 1080 TATTGGGAAG CACAGGTGGG CAATTCCTCT TGβTACCTCT ATGATGGAGA AGACGATACA 1140 CCCTCCTACC βTGGATTCCT CATTTTCTGG GGCTATATCA TTGTTCTCAA CACCATGGTA 1200 CCCATCTCTC TCTATGTCAG CGTGGAAGTG ATTCGTCTTG GACAGAGTCA CTTCATCAAC 1260 TGGGACCTGC AAATGTACTA TGCTGAGAAG GACACACCCG CAAAAGCTAG AACCACCACA 1320 CTCAATGAAC AGCTCGGβCA GATCCATTAT ATCTTCTCTG ATAAGACGGG GACACTCACA 1380 CAAAATATCA TGACCTTTAA AAAGTGCTGT ATCAACGGGC AGATATATGG GGACCATCGG 1440 GATGCCTCTC AACACAACCA CAACAAAATA GAGCAAGTTG ATTTTAβCTG GAATACATAT 1500 GCTGATGGGA AGCTTGCATT TTATGACCAC TATCTTATTG AGCAAATCCA GTCAGGGAAA 1560 GAGCCAGAAG TACGACAGTT CTTCTTCTTG CTCGCAGTTT GCCACACAGT CATGGTGGAT 1620 AGGACTGATG GTCAGCTCAA CTACCAGGCA GCCTCTCCCG ATGAAGGTGC CCTGGTAAAC 1680 GCTGCCAGGA ACTTTGGCTT TGCCTTCCTC GCCAGGACCC AGAACACCAT CACCATCAGT 1740 GAACTGGGCA CTGAAAβGAC TTACAATGTT CTTGCCATTT TGGACTTCAA CAGTGACCGG 1800 AAGCGAATGT CTATCATTGT AAGAACCCCA GAAGGCAATA TCAAGCTTTA CTGTAAAGGT 1860 GCTGACACTG TTATTTATGA ACGGTTACAT CGAATGAATC CTACTAAGCA AGAAACACAβ 1920 GATGCCCTGG ATATCTTTGC AAATGAAACT CTTAGAACCC TATGCCTTTG CTACAAGGAA 1980 ATTGAAGAAA AAGAATTTAC AGAATGGAAT AAAAAGTTTA TGGCTGCCAG TGTGGCCTCC 2040 ACCAACCGββ ACGAAGCTCT GGATAAAGTA TATGAGβAGA TTGAAAAAGA CTTAATTCTC 2100 CTGGGAGCTA CAGCTATTGA AGACAAGCTA CAGGATGGAG TTCCAGAAAC CATTTCAAAA 2160 CTTGCAAAAG CTGACATTAA GATCTGβGTG CTTACTGGAG ACAAAAAGGA AACTGCTGAA 2220 AATATAGGAT TTGCTTGTGA ACTTCTGACT CAAGACACCA CCATCTGCTA TGGGGAGGAT 2280 ATTAATTCTC TTCTTCATGC AAGGATGβAA AACCAGAGGA ATAGAGGTβG CGTCTACGCA 2340 AACTTTGCAC CTCCTGTGCA GGAATCTTTT TTTCCACCCG GTGGAAACCG TGCCTTAATC 2400 ATCACTGGTT CTTGCTTGAA TGAAATTCTT CTCGAGAAAA AGACCAAGAβ AAATAAGATT 2460 CTGAAGCTGA AGTTCCCAAG AACAGAAGAA GAAAGACGGA TGCGGACCCA AAGTAAAAGG 2520 AGGCTAGAAG CTAAGAAAGA GCAGCGGCAG AAAAACTTTG TGGACCTGGC CTGCGAGTGC 2580 AGCGCAGTCA TCTβCTβCCG CGTCACCCCC AAGCAGAAGG CCATGGTGGT GβACCTGGTG 2640 AAGAGGTACA AGAAAβCCAT CACGCTGGCC ATCGβAGATG GβGCCAATGA CGTβAACATβ 2700 ATCAAAACTG CCCACATTGG CGTTGGAATA AGTββACAAG AAGGAATGCA AGCTGTCATG 2760 TCGAGTGACT ATTCCTTTGC TCAGTTCCGA TATCTGCAGA GβCTACTGCT GGTGCATGGC 2820 CGATGGTCTT ACATAAGGAT GTGCAAGTTC CTACGATACT TCTTTTACAA AAACTTTGCC 2880 TTTACTTTGG TTCATTTCTG GTACTCCTTC TTCAATGGCT ACTCTGCGCA GACTGCATAC 2940 GAGGATTGGT TCATCACCCT CTACAACGTG CTGTACACCA GCCTGCCCGT 6CTCCTCAT6 3000 GGGCTGCTCG ACCAGGATGT GAGTGACAAA CTGAGCCTCC GATTCCCTGβ βTTATACATA 3060 GTGGGACAAA GAGACTTACT ATTCAACTAT AAGAGATTCT TTGTAAGCTT GTTβCATGGG 3120 GTCCTAACAT CGATGATCCT CTTCTTCATA CCTCTTGGAG CTTATCTGCA AACCGTAGGG 3180 CAGCATGGAG AβGCACCTTC CGACTACCAG TCTTTTGCCG TCACCATTGC CTCTGCTCTT 3240 GTAATAACAG TCAATTTCCA GATTGGCTTG GATACTTCTT ATTGGACTTT TGTGAATGCT 3300 TTTTCAATTT TTGGAAGCAT TGCACTTTAT TTTGβCATCA TβTTTβACTT TCATAGTGCT 3360 GGAATACATG TTCTCTTTCC ATCTGCATTT CAATTTACAG GCACAGCTTC AAACβCTCTG 3420 AGACAGCCAT ACATTTGGTT AACTATCATC CTGACTGTTG CTGTGTGCTT ACTACCCGTC 3480 GTTGCCATTC GATTCCTGTC AATGACCATC TGGCCATCAG AAAGTGATAA GATCCAGAAG 3540
CATCGCAAGC GGTTGAAGGC GGAGGAGCAG TGGCAGCGAC GGCAGCAGGT GTTCCGCCGG 3600
GGCGTβTCAA CGCGGCβCTC GGCCTACGCC TTCTCGCACC AGCGGGGCTA CGCGβACCTC 3660
ATCTCCTCCG GGCGCAGCAT CCGCAAGAAG CGCTCGCCGC TTGATGCCAT CGTGGCGβAT 3720
GGCACCGCGG AGTACAGGCG CACCGGGGAC AGCTGA 3756
Seq ID NO: C48 DNA Sequence Nucleic Acid Accession #: XM_ 044533 Coding sequence: 238..2751
1 11 21 31 41 51
1 i I I I I
GCTCTGCCCA AGCCGAβGCT GCGGGGCCGG CGCCβGCGGG AGGACTGCβG TGCCCCGCβG 60
AGGGGCTGAG TTTGCCAGGG CCCACTTGAC CCTGTTTCCC ACCTCCCGCC CCCCAGGTCC 120
GGAGGCGGGG GCCCCCGGGG CGACTCGGGG GCGGACCGCG GGGCGGAGCT GCCGCCCGTβ 180
AGTCCGGCCG AGCCACCTGA GCCCGAGCCG CGGGACACCG TCGCTCCTGC TCTCCGAATG 240
CTGCGCACCG CGATGGGCCT GAGGAGCTGG CTCGCCGCCC CATGβGGCGC GCTGCCGCCT 300
CGGCCACCGC TGGTGCTGCT CCTGCTβCTG CTGCTCCTGC TGCAGCCGCC GCCTCCGACC 360
TCββCβCTCA CCCCCCGGAT CAGCCTGCCT CTGGGCTCTG AAGAGCGGCC ATTCCTCAGA 420
TTCGAAGCTG AACACATCTC CAACTACACA GCCCTTCTGC TGAGCAGGGA TGGCAGGACC 480
CTGTACGTGG GTGCTCGAGA GGCCCTCTTT GCACTCAGTA GCAACCTCAG CTTCCTGCCA 540
GGCGGGGAβT ACCAGGAGCT GCTTTGGGGT GCAGACGCAG AGAAβAAACA GCAGTGCAGC 600
TTCAAGGGCA AGGACCCACA GCβCβACTGT CAAAACTACA TCAAGATCCT CCTGCCGCTC 660
AGCGGCAGTC ACCTGTTCAC CTβTGGCACA GCAGCCTTCA GCCCCATGTG TACCTACATC 720
AACATGGAGA ACTTCACCCT GGCAAGGGAC GAGAAGGGGA ATGTCCTCCT GGAAGATGGC 780
AAGβGCCGTT GTCCCTTCGA CCCGAATTTC AA6TCCACTG CCCTGGTGGT TGATGGCGAG 840
CTCTACACTG GAACAGTCAG CAGCTTCCAA GGGAATGACC CGGCCATCTC GCGGAGCCAA 900
AGCCTTCGCC CCACCAAGAC CGAGAGCTCC CTCAACTGβC TGCAAGACCC AGCTTTTGTG 960
GCCTCAGCCT ACATTCCT6A GAGCCTGβGC AGCTTGCAAG βCGATGATGA CAAGATCTAC 1020
TTTTTCTTCA GCGAGACTGG CCAGGAATTT GAGTTCTTTG AβAACACCAT TβTGTCCCGC 1080
ATTGCCCGCA TCTGCAAGGG CGATGAGGGT GGAGAGCGGG TGCTACAGCA GCGCTGGACC 1140
TCCTTCCTCA AGGCCCAGCT GCTGTGCTCA CGGCCCGACG ATGGCTTCCC CTTCAACGTG 1200
CTGCAGGATG TCTTCACGCT GAGCCCCAGC CCCCAGGACT GGCGTGACAC CCTTTTCTAT 1260
GGββTCTTCA CTTCCCAGTG GCACAGGβGA ACTACAGAAG GCTCTGCCGT CTGTGTCTTC 1320
ACAATGAAGG ATGTGCAGAG AGTCTTCAGC GGCCTCTACA AGGAGGTGAA CCGTGAGACA 1380
CAGCAGTGβT ACACCβTβAC CCACCCG6TG CCCACACCCC GGCCTGGAGC βTGCATCACC 1440
AACAGTGCCC GGGAAAGβAA GATCAACTCA TCCCTGCAGC TCCCAGACCG CGTGCTGAAC 1500
TTCCTCAAGβ ACCACTTCCT GATGGACββG CAGGTCCGAA GCCGCATGCT GCTGCTGCAG 1560
CCCCAGGCTC GCTACCAGCG CGTGGCTβTA CACCGCGTCC CTGGCCTGCA CCACACCTAC 1620
GATGTCCTCT TCCTGGGCAC TGGTGACGGC CGGCTCCACA AGβCAGTGAG CGTGGGCCCC 1680
CGGGTGCACA TCATTGAGGA GCTGCAGATC TTCTCATCGG GACAGCCCGT GCAGAATCTG 1740
CTCCTGGACA CCCACAGGGG GCTGCTGTAT GCGβCCTCAC ACTCGββCGT AGTCCAGGTG 1800
CCCATGGCCA ACTGCAGCCT GTACAGGAGC TGTGGGGACT GCCTCCTCGC CCGGGACCCC 1860
TACTGTGCTT GGAGCCGCTC CAGCTGCAAG CACGTCAGCC TCTACCAGCC TCAGCTGGCC 1920
ACCAGGCCGT GβATCCAββA CATCβAββGA GCCAGCGCCA AGGACCTTTG CAGCGCGTCT 1980
TCGGTTGTGT CCCCGTCTTT TGTACCAACA GGGGAGAAGC CATGTGAGCA AGTCCAGTTC 2040
CAGCCCAACA CAGTGAACAC TTTGGCCTβC CCGCTCCTCT CCAACCTGCC GACCCGACTC 2100
TGGCTACGCA ACGGGGCCCC CGTCAATGCC TCGGCCTCCT GCCACGTβCT ACCCACTββG 2160
GACCTGCTGC TGGTGGGCAC CCAACAGCTG GGGGAGTTCC AGTGCTGGTC ACTAGAG6AG 2220
GGCTTCCAGC AGCTGGTAGC CAGCTACTGC CCAGAGGTGG TGGAGGACGG GGTGGCAGAC 2280
CAAACAGATG AGGGTGGCAG TGTACCCGTC ATTATCAβCA CATCGCGTGT GACTGCACCA 2340
GCTGGTGGCA AGGCCAGCTG GGGTGCAGAC ACGTCCTACT GGAAGGAGTT CCTGGTGATG 2400
TGCACGCTCT TTGTGCTGGC CGTGCTGCTC CCAGTTTTAT TCTTGCTCTA CCGGCACCGβ 2460
AACAGCATGA AAGTCTTCCT GAAGCAGGGG GAATGTGCCA GCGTGCACCC CAAGACCTGC 2520
CCTGTGGTGC TGCCCCCTGA GACCCGCCCA CTCAACGGCC TAGβGCCCCC TAGCACCCCG 2580
CTCGATCACC GAGGGTACCA GTCCCTGTCA GACAGCCCCC CGGGGTCCCG AGTCTTCACT 2640
GAGTCAGAGA AGAβGCCACT CAGCATCCAA GACAGCTTCG TGGAGGTATC CCCAGTGTGC 2700
CCCCGGCCCC GGGTCCGCCT TGGCTGGGAG ATCCGTGACT CTGTGGTGTG AGAGCTGACT 2760
TCCAGAGGAC GCTGCCCTGG CTTCAGGGGC TGTβAATGCT CGGAGAGGGT CAACTGGACC 2820
TCCCCTCCGC TCTGCTCTTC GTGGAACACG ACCGTGGTGC CCGGCCCTTG GGAGCCTTGG 2880
GGCCAGCTGG CCTGCTGCTC TCCAGTCAAG TAGCGAAGCT CCTACCACCC AGACACCCAA 2940
ACAGCCGTGG CCCCAGAGβT CCTGβCCAAA TATGGGGGCC TGCCTAGβTT GGTGGAACAG 3000
TGCTCCTTAT GTAAACTGAG CCCTTTGTTT AAAAAACAAT TCCAAATGTG AAACTAGAAT 3060
GAGAGGβAAG AGATAGCATG GCATGCAGCA CACACGGCTG CTCCAGTTCA TGGCCTCCCA 3120
GGGGTGCTGG GGATGCATCC AAAGTGGTTG TCTGAGACAG AGTTGGAAAC CCTCACCAAC 3180
TGGCCTCTTC ACCTTCCACA TTATCCCGCT GCCACCGGCT GCCCTGTCTC ACTGCAGATT 3240
CAGGACCAGC TTGGGCTGCG TβCβTTCTGC CTTGCCAβTC AGCCGAGGAT GTAGTTGTTG 3300
CTGCCGTCGT CCCACCACCT CAGG6ACCAG AββGCTAGGT TGGCACTGCβ GCCCTCACCA 3360
GGTCCTGGGC TCGGACCCAA CTCCTGGACC TTTCCAGCCT GTATCAGGCT GTGGCCACAC 3420
GAGAGGACAG CGCGAGCTCA GGAGAGATTT CGTGACAATG TACGCCTTTC CCTCAGAATT 3480
CAGGGAAGAβ ACTGTCβCCT GCCTTCCTCC GTTGTTGCGT GAGAACCCGT βTβCCCCTTC 3540
CCACCATATC CACCCTCGCT CCATCTTTGA ACTCAAACAC GAGGAACTAA CTGCACCCTG 3600
GTCCTCTCCC CAGTCCCCAG TTCACCCTCC ATCCCTCACC TTCCTCCACT CTAAGGGATA 3660
TCAACACTGC CCAGCACAGG GGCCCTGAAT TTATGTGGTT TTTATACATT TTTTAATAAG 3720
ATGCACTTTA TGTCATTTTT TAATAAAGTC TGAAGAATTA CTGTTT 3766
Seq ID NO: C49 DNA Sequence
Nucleic Acid Accession ft: NM_007019.1
Coding sequence: 41..580
1 11 21 31 41 51
I I I I I I
GGCACGAGCG AGTTCCTGTC TCTCTGCCAA CGCCGCCCGG ATGGCTTCCC AAAACCGCGA CGCAGCCGCC ACTAGCGTCG CCGCCGCCCG TAAAGGAGCT GAGCCGAGCG Gββececcec 120
CCGGGGTCCG GTGGGCAAAA GGCTACAGCA GGAGCTGATG ACCCTCATGA TCTCTβeccA 180
TAAAGGGATT TCTGCCTTCC CTGAATCAGA CAACCTTTTC AAATGGGTAG GGACCATCCA 240
TGGAGCAGCT GβAACAGTAT ATGAAGACCT GAGGTATAAG CTCTCGCTAG AGTTCCCCAG 300
TGGCTACCCT TACAATGCGC CCACAGTGAA GTTCCTCACG CCCTGCTATC ACCCCAACGT 360
GGACACCCAG GGTAACATAT GCCTGGACAT CCTGAAGβAA AAGTGGTCTG CCCTGTATGA 420
TGTCACGACC ATTCTGCTCT CCATCCAGAG CCTTCTAGGA GAACCCAACA TTβATAβTCC 480
CTTGAACACA CATGCTGCCG AGCTCTGGAA AAACCCCACA GCTTTTAAGA AGTACCTGCA 540
AGAAACCTAC TCAAAGCAGG TCACCAGCCA GGAGCCCTCA CCCAGGCTGC CCAGCCTGTC 600 0 CTTGT6TCGT CTTTTTAATT TTTCCTTAGA TGGTCTGTCC TTTTTGTGAT TTCTGTATAG 660
GACTCTTTAT CTTGAGCTGT GGTATTTTTG TTTTGTTTTT GTCTTTTAAA TTAAGCCTCG 720
GTTGAGCCCT TGTATATTAA ATAAATβCAT TTTTGTCCTT TTTTAAAAAA AAAAAAAAAA 780
AAA 783 5 Seq ID NO: C50 DNA Sequence
Nucleic Acid Accession ff: NM_014584.1
Coding sequence: 227..1633
11 21 31 41 0
GCACGAGCCC CGGGCTGCCG GCGCGGβCGC CGCGGCACGT CCACAGGCTG GGTCGCGAGG 60 TGGCGATCGC TGAGAGGCAG GAGGGCCGAG βCCβGCCTGG GAGβCβGCCC GGAGGTGGGG 120 CGCCGCTGGG GCCGGCCCGC ACGGGCTTCA TCTGAGGGCG CACGGCCCGC GACCGAGCGT 180 GCGGACTGβC CTCCCAAGCG TGGGGCGACA AGCTβCCGGA GCTGCAATGG GCCCCGGCTG 240 5 GGGATTCTTG TTTGGCCTCC TGGGCGCCGT GTGGCTβCTC AGCTCGGGCC ACGGAGAGGA 300 GCAGCCCCCG GAGACAGCGG CACAGAGGTG CTTCTGCCAβ GTTAGTGGTT ACTTGGATGA 360 TTGTACCTGT GATGTTGAAA CCATTGATAG ATTTAATAAC TACAGGCTTT TCCCAAGACT 420 ACAAAAACTT CTTGAAAGTG ACTACTTTAG GTATTACAAG GTAAACCTGA AGAGGCCGTG 480 TCCTTTCTGG AATGACATCA GCCAβTGTGG AAGAAGGGAC TGTGCTGTCA AACCATGTCA 540 0 ATCTCATGAA GTTCCTGATG GAATTAAATC TGCGAGCTAC AAGTATTCTG AAGAAGCCAA 600 TAATCTCATT GAAGAATGTG AACAAGCTGA ACGACTTGGA GCAβTββATG AATCTCTGAG 660 TGAGGAAACA CAGAAGGCTG TTCTTCAGTG GACCAAGCAT GATGATTCTT CAGATAACTT 720 CTGTGAAGCT GATGACATTG AGTCCCCTGA AGCTGAATAT GTAGATTTGC TTCTTAATCC 780 TGAGCGCTAC ACTGGTTACA AGGGACCAGA TGCTTGβAAA ATATGGAATG TCATCTACGA 840 5 AGAAAACTGT TTTAAGCCAC AGACAATTAA AAGACCTTTA AATCCTTTCβ CTTCTGβTCA 900 AGGGACAAGT GAAGAGAACA CTTTTTACAG TTGβCTAGAA GGTCTCTGTG TAGAAAAAAG 960 AGCATTCTAC AGACTTATAT CTGGCCTACA TGCAAβCATT AATGTGCATT TGAβTGCAAG 1020 ATATCTTTTA CAAGAGACCT GGTTAGAAAA GAAATGGGGA CACAACATTA CAGAATTTCA 1080 ACAGCGATTT GATGGAATTT TGACTGAAGG AGAAGGTCCA AGAAGGCTTA AGAACTTGTA 1140 0 TTTTCTCTAC TTAATAGAAC TAAGGGCTTT ATCCAAAGTG TTACCATTCT TCGAGCGCCC 1200 AGATTTTCAA CTCTTTACTG GAAATAAAAT TCAGβATGAG GAAAACAAAA TGTTACTTCT 1260 GGAAATACTT CATGAAATCA AGTCATTTCC TTTGCATTTT GATGAGAATT CATTTTTTGC 1320 TGGGGATAAA AAAGAAGCAC ACAAACTAAA GGAGGACTTT CGACTβCATT TTAGAAATAT 1380 TTCAAGAATT ATββATTGTG TTGGTTGTTT TAAATGTCGT CTGTGGGGAA AGCTTCAGAC 1440 5 TCAGGGTTTG GGCACTβCTC TGAAGATCTT ATTTTCTGAG AAATTGATAG CAAATATGCC 1500 AGAAAGTGGA CCTAGTTATG AATTCCATCT AACCAGACAA GAAATAGTAT CATTATTCAA 1560 CβCATTTGGA AGAATTTCTA CAAGTGTGAA AGAATTAGAA AACTTCAGGA ACTTGTTACA 1620 GAATATTCAT TAAAGAAAAC AAGCTGATAT GTGCCTGTTT CTGGACAATG GAGGCGAAAG 1680 AGTGGAATTT CATTCAAAGG CATAATAGCA ATGACAGTCT TAAGCCAAAC ATTTTATATA 1740 0 AACTTβCTTT TGTAAAGGAG AATTATATTG TTTTAAGTAA ACACATTTTT AAAAATTGTG 1800 TTAAGTCTAT GTATAATACT ACTGTGAGTA AAAGTAATAC TTTAATAATG TGGTACAAAT 1860 TTTAAAGTTT AATATTGAAT AAAAGGAGGA TTATCAAATT CATATATGAT AAAAGTGAAT 1920 GTTCTAAGTC TCTCAAACTA GCβTTTTATG TAATAATATG TAATATAAAT AAAACTATGG 1980 TAAATGTGAC AAGCATTTAA TAGGAAAATG CTAAGGAGGC CTCATAAATG ACCCATAATT 2040 5 ACCAACGTAG AATTTTTCAG TACATTTAGG GTTGCTGGAT TTACCAAATA AAAATAAAGA 2100 TTGCCCAGTT AGATTTGAAT TTCAβATAAA CAATTAGTTT TTTAATATTT TACATGGAAT 2160 ATTTGGAAAA TACTTATACT AAAAAATTAT TTGTTTGAAA TTCACATTTA ACTGGGAGTC 2220 TTGTATTTTA TCTGGCAATC CTAAAATACA TTββTATβAA ACAAATCACT TTTAGAAGTA 2280 TATTβCTATT TTGATTGGGT TGTTTTTGTG TGTAGAAACG TACAATAACA ACTCAAAGGC 2340 0 ACAGGAGATT TCTAAACATT GTGAAAAGTT GAATAGATTA TATATTTATT CTCATAATAC 2400 TTTCACTAAT ACTAAATAAA ATTTGGGGAA CACTTTTTAT TTTTATATAA TTTCCAATTT 2460 ACAGAAAAGT TTCAAAAATA GTACAAAGAG CTCTCTTACC CAGATTCACT AATTGTTCAT 2520 ACGTGCTTTA TCTTTCATGC TTTCTCTGTA CACACACACA CACACACAAA TTTTTCCTCA 2580 ATCATTTGAA AGTCAGTTAT AGGCATCATG CCCCTTAAAC CCTAAATACT TCAGTGTGTA 2640 5 ATACTGAATA ATTACTAAAA ATGATTTTCT CAGAAAAAAA AACTCCCACA ATTCTGGAAC 2700 TATAATACTG TAAGCCTTAG AATAAATAAT ACTTTCAAGT TCCAATCTAA AGTTCTTTTT 2760 GAGTTTTβTT βCCCGTTTTA TGCTTGATGT GTATAGTAAT AGGGTAGGCT ATTTATTTTA 2820 TTAAAATTTT TTTTAGAGAC AAGGTTTTGC TGTGTTGCCC AAGCTGGAAC I TTGAACGACT 2880 GβGCTGAAGT GATCTTCCCA CCTCAGCCTC CCAAGTAGCT GGGAATACAG ! GTGTCTGCCA 2940
70 CCATACCCAG TTTCATTTTT GTTTTTTATA CCCGAA6TTC ATTTCCTTTG 1 TCTCCCTAAA 3000 ACTGAACTGT AATTTTGGGA GGTTTTCATT AGTGGAA6CT CTTCATTTAT 1 AAAGCTATTT 3060 GAAGGGGTTT AGGAATTTAT ATCACATGGT AATTGTAβAG AAAAAGAAGC ! TATATACCTC 3120 AAAATCGTGC CCTCTTTACA TATGTCTTAT CAGβTATAAC ATGTTGAAAT ' GTCACATTAG 3180 TAGTAAAGTG GGGTTTATTT ATATAGTGGT TAAGAAATGT CAGTTTACAC 1 TGCTβTATAC 3240
75 TTCTTCTTCT GTGTCCCTAA GGCCTGGTAC AGTβCCAACC ACATACTTGG ! TATCCAATAA 3300 ATATTTGTTG GATGAAAAAA AAAAAAAAAA AAAA 3334
_. Seq ID NO: C51 DNA Sequence oU Nucleic Acid Accession #: NM_002888.1 Coding sequence: 37.. 23
11 21 CCACGTCCGG GβTGCCGAGC CAACTTTCCT βCGTCCATGC AGCCCCGCCG GCAACGGCTG 60
CCCGCTCCCT GGTCCβGβCC CAβGGGCCCG CGCCCCACCG CCCCGCTGCT CGCGCTGCTG 120
CTGTTGCTCG CCCCGGTGGC GGCGGCGGCG GGGTCCGGGG GCCCCGACGA CCCTGGβCAG 180
CCTCAGGATG CTGGGGTCCC GCGCAGGCTC CTGCAGCAGA AGβCβCβCβC GGCGCTTCAC 240
TTCTTCAACT TCCGGTCCGG CTCGCCCAGC GCGCTGCGAG TGCT6GCCGA 6GTGCAGGAG 300
GGCCGCβCβT GGATTAATCC AAAAβAGGGA TGTAAAβTTC ACβTββTCTT CAGCACAGAG 360
CGCTACAACC CAGAGTCTTT ACTTCAGβAA GGTGAGGGAC GTTTGGGGAA ATGTTCTGCT 420
CGAGTGTTTT TCAAGAATCA GAAACCCAGA CCAACCATCA ATGTAACTTG TACACGGCTC 480
ATGGAGAAAA AGAAAAGACA ACAAGAGGAT TACCT6CTTT ACAACCAAAT GAAGCAACTG 540
AAAAACCCCT TGGAAATAGT CAGCATACCT GATAATCATC GACATATTGA TCCCTCTCTG 600
AGACTCATCT GGGATTTGGC TTTCCTTGGA AGCTCTTACG TGATGTGGGA AATGACAACA 660
CAGGTGTCAC ACTACTACTT GGCACAGCTC ACTAGTGTGA GGCAGTGGGT AAGAAAAACC 720
TGAAAATTAA CTTGTGCCAC AAGAGTTACA ATCAAAGTGG TCTCCTTAGA CTGAATTCAT 780
GTGAACTTCT AATTTCATAT CAAGAGTTGT AATCACATTT ATTTCAATAA ATATGTGAGT 840
TCCTGC 846
Seq ID NO: C52 DNA Sequence
Nucleic Acid Accession ff: NM_005409.3
Coding sequence: 94..378
1 11 21 31 41 51
I I I I I I
TTCCTTTCAT GTTCAGCATT TCTACTCCTT CCAAGAAGAβ CAGCAAAGCT GAAGTAGCAG 60
CAACAGCACC AGCAGCAACA GCAAAAAACA AACATGAGTG TGAAGGCCAT GGCTATAGCC 120
TTGβCTGTGA TATTGTGTGC TACAGTTGTT CAAGGCTTCC CCATGTTCAA AAGAGGACGC 180
TGTCTTTGCA TAGGCCCTGβ GGTAAAAGCA GTGAAAGTGG CAGATATTGA GAAAGCCTCC 240
ATAATGTACC CAAGTAACAA CTGTGACAAA ATAGAAGTGA TTATTACCCT GAAAGAAAAT 300
AAAGGACAAC GATGCCTAAA TCCCAAATCG AAGCAAGCAA GGCTTATAAT CAAAAAAGTT 360
GAAAGAAAGA ATTTTTAAAA ATATCAAAAC ATATGAAGTC CTGGAAAAGG GCATCTGAAA 420
AACCTAβAAC AAGTTTAACT GTGACTACTG AAATGACAAG AATTCTACAG TAGGAAACTG 480
AGACTTTTCT ATGGTTTTGT GACTTTCAAC TTTTGTACAG TTATGTGAAG GATGAAAGβT 540
GGGTGAAAGG ACCAAAAACA GAAATACAGT CTTCCTGAAT GAATGACAAT CAGAATTCCA 600
CTGCCCAAAG GAGTCCAGCA ATTAAATGGA TTTCTAGGAA AAGCTACCTT AAGAAAGGCT 660
GGTTACCATC GGAGTTTACA AAGTβCTTTC ACGTTCTTAC TTGTTGTATT ATACATTCAT 720
GCATTTCTAG GCTAGAGAAC CTTCTAGATT TGATGCTTAC AACTATTCTG TTβTGACTAT 780
GAGAACATTT CTGTCTCTAG AAGTTATCTG TCTGTATTGA TCTTTATGCT ATATTACTAT 840
CTβTGGTTAC AGTGGAGACA TTGACATTAT TACTGGAGTC AAGCCCTTAT AAGTCAAAAG 900
CATCTATGTG TCGTAAAGCA TTCCTCAAAC ATTTTTTCAT GCAAATACAC ACTTCTTTCC 960
CCAAATATCA TGTAGCACAT CAATATGTAG GGAAACATTC TTATGCATCA TTTGGTTTGT 1020
TTTATAACCA ATTCATTAAA TGTAATTCAT AAAATGTACT ATGAAAAAAA TTATACGCTA 1080
TGGGATACTG GCAACAGTGC ACATATTTCA TAACCAAATT AβCAGCACCG GTCTTAATTT 1140
GATGTTTTTC AACTTTTATT CATTGAGATG TTTTGAAGCA ATTAGGATAT GTGTGTTTAC 1200
TGTACTTTTT GTTTTGATCC GTTTGTATAA ATGATAβCAA TATCTTCGAC ACATTTGAAA 1260
TACAAAATGT TTTTGTCTAC CAAAGAAAAA TGTTGAAAAA TAAGCAAATG TATACCTAGC 1320
AATCACTTTT ACTTTTTGTA ATTCTGTCTC TTAGAAAAAT ACATAATCTA ATCAATTTCT 1380
TTGTTCATGC CTATATACTG TAAAATTTAG GTATACTCAA GACTAβTTTA AAGAATCAAA 1440
GTGATTTTTT TCTCTAATAA ACTACCACAA CCTTTCTTTT TTAAAAAAAA AAA 1493
Seq ID NO: C53 DNA Sequence
Nucleic Acid Accession #: FGENESH predicted
Coding sequence: 1..609
1 11 21 31 41 51 l l l l l !
ATGCTGCGGC AGGTGCTTCG CAGAGGGCTC CAGTCGTTCT GCCACAGGCT GGGTTTGTGC 60
GTGAGCCGGC ACCCGGTCTT TTTCCTCACC GTGCCCGCAG TCCTGACAAT CACCTTCGGC 120
CTCAGCGCGC TCAACCGCTT CCAGCCCGAβ GGCGACCTGG AGCGCCTGGT CGCTCCCAGC 180
CACAGCCTGG CCAAGATCGA GCGCAGCCTG GCCAGCAGCC TTTTCCCCCT GGACCAGTCC 240
AAAAGCCACC TCTATTCGβA CTTACACACC CCTβGGAGGT ATGGCAGGGT GATCCTCCTC 300
TCCCCAACCG GGGACAATAT TTTGCTCCAG GCTGAββGβA TCCTGCAGAC CCACCGAGCC 360
GTGCTGGAAA TGAAGGTGAA CCACAAGGGC TATAATTATA CTTTTTCCCA TCTGTGTGTG 420
TTGAGAAATC AGβATAAGAA ATGCGTGCTG GATGATATTA TTTCAGTβCT A6AGGATCTC 480
AG6CAGGCTG CCGTCTCCAA TAACACAACA GCCAGGGTGC AAGTGAβGTA TCCCAACACT 540
AAATTAAAGG TATGCTCCTT CTGCATGCTT CTGCCAATTA AAGAGGCAGC ACTTCATTTC 600
TTGCCCTAA 609
Seq ID NO: C54 DNA Sequence
Nucleic Acid Accession ft: NM_002438.1
Coding sequence: 104..4474
1 11 21 31 41 51
I I I I I I ββGAACTTGG ATTAGGTGGA GAGGCAβTTβ GGGGGCCTCG TTGTTTTGCG TCTTAGTTCC 60
GCCCTCCTβT CCATCAGGAG AAGGAAAGGA TAAACCCTGG GCCATGAGGC TACCCCTGCT 120
CCTGGTTTTT GCCTCTGTCA TTCCGGGTGC TGTTCTCCTA CTGGACACCA GGCAATTTTT 180
AATCTATAAT GAAGATCACA AGCGCTGCGT CGATGCAGTG AGTCCCAGTG CCGTCCAAAC 240
CGCAβCTTCC AACCAGGATG CCGAATCACA GAAATTCCGA TGGGTGTCCG AATCTCAGAT 300
TATGAGTGTT GCATTTAAAT TATGCCTGGβ AβTGCCATCA AAAACAGACT GGGTTGCTAT 360
CACTCTCTAT GCCTGTGACT CAAAAAGTβA ATTTCAGAAA TGGβAβTβCA AAAATGACAC 420
ACTTTTGGGG ATCAAAGGAG AAGATTTATT TTTTAACTAC GGCAACAGAC AAGAAAAGAA 480 TATTATGCTC TACAAGGGAT CGGGTTTATG GAGCAGGTGG AAGATCTATG GAACCACAGA 540 CAATCTGTGC TCCAGAGGTT ATGAAGCCAT GTATACGCTA CTAGGCAATG CCAATGGAGC 600 AACCTGTGCA TTCCCGTTCA AGTTTGAAAA CAAGTGGTAC GCAGATTGCA CGAβTGCTGG 660 GCGGTCGGAT GGATGGCTCT GCTβCGGAAC CACTACTGAC TATGACACAG ACAAGCTATT 720 TGGATATTGT CCATTGAAAT TTGAGGGCAG TGAAAGCTTA TGGAATAAAG ACCCGCTGAC 780
CAGCGTTTCC TACCAGATAA ACTCCAAATC CGCTTTAACG TGGCACCAAG CGAGGAAAAG 840
CTGCCAACAA CAGAACGCTG AGCTCCTGAG CATCACAGAG ATACATGAGC AAACATACCT 900
GACAGGATTA ACCAGTTCCT TGACCTCAGG ACTCTGGATT GGACTTAACA GTCTGAGCTT 960
CAACAGCGGT TGGCAGTGGA GTGACCGCAβ TCCTTTCCGA TATTTGAACT GGTTACCAGG 1020
AAGTCCATCA GCTGAACCTG GAAAAAGCTG TGTGTCACTA AATCCTGGAA AAAATGCTAA 1080
ATGGGAAAAT CTGGAATGTG TTCAGAAACT GGGCTATATT TGCAAAAAGG GCAACACCAC 1140
TTTAAATTCT TTTGTTATTC CCTCAGAAAG TGATGTGCCT ACTCACTGTC CTAGTCAGTG 1200 βTGGCCGTAT GCCGβTCACT βTTACAAβAT TCACAGAGAT GAGAAAAAAA TCCAGAGGGA 1260
TGCTCTGACC ACCTGCAGGA AGGAAGGCGG TGACCTCACA AGTATCCACA CCATCGAGGA 1320
ATTGGACTTT ATTATCTCCC AGCTAββATA TGAGCCAAAT GACGAATTGT GGATCGGCTT 1380
AAATGACATT AAGATTCAAA TGTACTTTGA GTGGAGTGAT GGGACCCCTG TAACGTTTAC 1440
CAAATGGCTT CGTGGAGAAC CAAGCCATβA AAACAACAGA CAGGAGGATT GTGTGGTGAT 1500
GAAAGGCAAG GATGGGTACT GGGCAGATCG GGGCTGTGAG TGGCCTCTTG GCTACATCTG 1560
CAAGATGAAA TCACGAAGCC AAGGTCCAβA AATAGTGβAA βTCβAAAAAG GCTGCAGGAA 1620
AGGCTGβAAA AAACATCACT TTTACTβCTA TATGATTG6A CATACGCTTT CAACATTTGC 1680
AGAAGCAAAC CAAACCTGTA ATAATGAGAA TGCTTATTTA ACAACTATTG AAGACAGATA 1740
TGAACAAGCC TTCCTGACTA GTTTCGTTGG CTTAAGGCCT GAAAAATATT TCTβGACAGG 1800
ACTTTCAGAT ATACAAACCA AAGGβACTTT TCAGTGGACC ATCGAGGAAG AGGTTCGGTT 1860
CACCCACTGG AATTCAGATA TGCCAGGGCG AAAGCCAGGG TGTGTTGCCA TGAGAACCGG 1920
GATTGCAGGG GβCTTATGGG ATGTTTTGAA ATGTGATGAA AAGGCAAAAT TTGTGTGCAA 1980
GCACTGGGCA GAAGGAGTAA CCCACCCACC GAAGCCCACβ ACGACTCCCG AACCCAAATG 2040
TCCGβAGGAT TG6GGCGCCA GCAGTAGAAC AAGCTTGTGT TTCAAGCTGT ATGCAAAAGG 2100
AAAACATGAG AAGAAAACGT GGTTTGAATC TCGAGATTTT TGTCGAGCTC TGGGTGGAGA 2160
CTTAβCTAGC ATCAATAACA AAGAGGAACA GCAAACAATA TGGCGATTAA TAACAGCTAG 2220
TGGAAGCTAC CACAAACTGT TTTGβTTβββ ATTGACATAT GGAAGCCCTT CAβAAGGTTT 2280
TACTTGGAGT GATGGTTCTC CTGTTTCATA TGAAAACTGG GCTTATGGAG AACCTAATAA 2340
TTATCAAAAT GTTGAATACT GTGGTGAβCT GAAAGGTGAC CCTACTATGT CTTGGAATGA 2400
TATTAATTGT GAACACCTTA ACAACTGGAT TTGCCAGATA CAAAAAGGAC AAACACCAAA 2460
ACCTGAGCCA ACACCAGCTC CTCAAGACAA TCCACCAGTT ACTGAAGATβ 6GTGGGTTAT 2520
TTACAAAGAC TACCAGTATT ATTTCAGCAA AGAβAAβGAA ACCATGGACA ATGCGCGAGC 2580
GTTTTGCAAG AβGAATTTTG GTGATCTTGT TTCTATTCAA AGTGAAAGTG AAAAGAAGTT 2640
TCTATGGAAA TATGTAAACA GAAATGATGC ACAGTCTGCA TATTTTATTG GTTTATTGAT 2700
CAGCTTββAT AAAAAβTTTG CTTGGATGGA TGGAAGCAAA GTGβATTACG TGTCTTGGβC 2760
CACAGGTGAA CCCAATTTTG CAAATGAAGA TGAAAACTGT GTGACCATGT ATTCAAATTC 2820
AGGGTTTTGG AATGACATTA ACTGTGGCTA TCCAAACGCC TTCATTTGCC AGCGACATAA 2880
CAGTAGTATC AATGCTACCA CAGTTATGCC TACCATGCCC TCGGTCCCAT CAGGGTGCAA 2940
GGAAGGTTGG AATTTCTACA GCAACAAGTG TTTCAAAATG TTTGGATTTA TGGAAGAAGA 3000
AAGAAAAAAT TGGCAAGAGG CACGAAAAGC TTGTATAGGC TTTGβAβGGA ATCTGGTCTC 3060
CATACAAAAT GAAAAAGAGC AAGCATTTCT TACCTATCAC ATGAAGGACT CCACTTTCAG 3120
TGCCTGGACT GGGCTGAATG ATGTCAATTC AGAACACACG TTCCTTTGGA CGβATGGACG 3180
AGGAGTCCAT TACACAAACT GGGGGAAAGG TTACCCTGGT G6AAGAAGAA GCAGTCTTTC 3240
TTATGAAGAT GCTGACTGTG TTGTTATTAT TGGAGGTGCA TCAAATGAAG CAGGAAAATG 3300
GATββATGAT ACCTGCGACA GTAAACGAGG CTACATATGC CAGACACGAT CCGACCCTTC 3360
CTTGACTAAT CCTCCAGCAA CGATTCAAAC AGATGGCTTT GTTAAATATG GCAAAAGCAG 3420
CTATTCACTC ATGAGACAAA AATTTCAATG βCATGAAGCG GAGACATACT GCAAGCTTCA 3480
CAATTCCCTT ATAGCCAGCA TTCTGGATCC CTACAGTAAT GCATTTGCβT GGCTGCAGAT 3540
GGAAACATCT AATGAACGTG TGTGGATCGC CCTCAACAGT AACTTGACTG ATAATCAATA 3600
CACTTGGACT GATAAGTGGA GGGTGAGGTA CACTAACTGG GCTGCTGATG AGCCCAAATT 3660
GAAATCAGCA TGTGTTTATC TGGATCTTGA TGGCTACTGG AAGACAGCAC ATTGCAATGA 3720
AAGTTTTTAC TTTCTCTGTA AAAGATCAGA TGAAATCCCT GCTACTGAAC CCCCACAACT 3780
GCCTGGCAGA TGCCCGGAGT CAGATCACAC AGCATGGATT CCTTTCCATG GTCACTGTTA 3840
CTATATTGAG TCCTCATATA CAAGAAACTG GGGCCAAGCT TCTCTGGAAT GTCTTCGAAT 3900
GGβTTCCTCT CTGGTTTCCA TTGAAAGTGC TGCAGAATCC AGTTTTCTGT CATATCGGGT 3960
TGAGCCACTT AAAAGTAAAA CCAATTTTTG GATAG6ATT6 TTCAGAAATG TTGAAGGGAC 4020
GTGβCTGTGG ATAAATAACA GTCCGGTCTC CTTTGTCAAC TGGAACACAG GAGATCCCTC 4080
TGGTGAACGG AATGATTGTG TAGCTTTACA TGCβTCTTCT GGGTTTTGGA GTAATATTCA 4140
CTGTTCTTCC TACAAAGGAT ATATTTGTAA AAGACCAAAA ATTATTGATG CTAAACCTAC 4200
TCATGAATTA CTTACAACAA AAGCTGACAC AAGGAAGATG GACCCTTCTA AACCGTCTTC 4260
CAACGTGGCC GGAGTAGTCA TCATTGTβAT CCTCCTGATT TTAACGGGTG CTGGCCTTGC 4320
CGCCTATTTC TTTTATAAGA AAAGACGTβT βCACCTACCT CAAβAGGGCG CCTTTGAAAA 4380
CACTCTGTAT TTTAACAGTC AGTCAAGCCC AGGAACTAGT GATATGAAAG ATCTCGTGGG 4440
CAATATTGAA CAGAATGAAC ACTCGGTCAT CTAGTACCTC AATGCGATTC TGAGATATTT 4500
GAATTTCATA AAATTGTAAC TGAAATTTAA AATTTTTAGT TCAATGTGAT TGTTTTCTTT 4560
AAAATGAGTA CTGAATTGTA CTGGTCTGTC CTTTTTTCCT TTGCCTAATT GAAGAAATAA 4620
TTGCTTGTTT TCTAGCCTGG CAAGATATTT TCATAAAAGA GGGATAACAA TGCTGATTAC 4680
TACCTTTTAA AATATTTTAG ATAAATGCAC AGCACCACAG CACCACATCT AAGCATTAGT 4740
GATGGGTAGC TGATGTCAGC TTCATGTGGA TTTTAAGCAC TCTAGAAACA ATGAAGCTTC 4800
TTGGCATATT TTAAGGAGCT CCCAAAATGT GTTACCTATT AAATTGTAAC TCAGCAAGTA 4860
GAAGACCATT TGAAAAGTCA GβTACAAATT TCCTCAAGTG GCATAAAAAT GTAGTCAGTT 4920
TTCTCTTTTA CCAGTTTTTA TTTCCACTCC AATTATTTAG AACTTTATTT GTACATGTGC 4980
AGAAGAATAA GGCAGCTGAG AATCTTGTTT CCCCCAAGAβ AGTTTTACAG GCTGAGTGTT 5040
GCAAATGTβT TCTTTGTCCT GTTATATGTA TATCAGβAAT ACAAGGATGT GAAATAAAAC 5100
TGTAAATTTG CATAACTGGA TGTACTTAGA TAATGTGAAA TAAACATTAA AβACAAGGTC 5160
TATTTTTAAT AAAAAAAAAA AAAAA 5185
Seq ID NO: C55 DNA Sequence
Nucleic Acid Accession #: NM_024574.2
Coding sequence: 424..2130
11 21 31 41 51
I I I I I I
AGTGCGACTA GCGGCGGCCG GCGAAGCCCG CGCCAGCCCC GCGGGTCGCT GCGGCATCCT 60 CCCGCCGCCC AGCCCCCGCA CGCTCCCTGC AGTTTAAAAG GACCTCCCGC CGCTTCTCGG 120 CGCTGCCCCG GGATTCCCCA GCCCCGCGCβ GCTCCCTACT CCACTTCGCA GCAACTTCGG 180
CGACCGCGCG CCGCCCGCCC TCGCCCGCCT TTGAAGTTTG CTGTGCCGAC CGCAAAGTTβ 240 ββACACTTCA GCGGATTGAA TTTTTCTCTT TTATCTGCCT CCGTCCCCGC CCTCCAGGCT 300
TCTCGTTCCT GGATATTGGT GCTTAGCATC TTGGCAββGT CCGGGGACGT GGACTATTTC 360
GCACACCACA CCAGGGGGAG GGATTTTTTT CTATTTTCCC TACGAAAAAC AGATCTTTTT 420
AAGGATGGTG CTGCTCCACT GGTGCCTGCT GTGGCTCCTG TTTCCACTCA GCTCAAGGAC 480
CCAGAAGTTA CCCACCCGGG ATGAGGAACT TTTTCAGATG CAGATCCGGG ACAAGGCATT 540
TTTTCATGAT TCGTCAGTAA TTCCAGATGG AGCTGAAATT AGCAGTTATC TCTTTAGAGA 600
TACACCTAAA AGGTATTTCT TTGTG6TTGA AGAAGACAAT ACTCCATTAT CAGTCACAGT 660
GACGCCCTGT βATGCGCCTT TGGAGTGGAA GCTGAGCCTC CAGGAGCTGC CAGAGGACAG 720
GAβCGGGβAA GGCTCAGGTG ATCTGGAACC TCTTGAGCAG CAGAAGCAGC AGATCATTAA 780
TGAGGAAGβC ACTGAGTTAT TCTCCTACAA AGGCAATGAT GTTGAGTATT TTATATCGTC 840
TAGTTCCCCA TCCGβTTTAT ATCAGTTGGA TCTTCTTTCA ACAGAGAAAG ACACACATTT 900
CAAAGTATAT GCCACCACAA CTCCAGAATC TGATCACCCA TACCCTGAGT TACCCTATGA 960
CCCAAGAGTA GATGTGACCT CACTGGGGCG CACCACβGTC ACTTTGGCCT GβAAACCAAG 1020
CCCCACTGCC TCTTTGCTGA AACAACCCAT TCAGTACTGT GTGGTCATCA ACAAAGAGCA 1080
CAATTTCAAA AGTCTCTGTG CAGTGGAAGC AAAACTGAGT GCAGATGATβ CTTTTATGAT 1140
GGCACCGAAA CCTGGTCTGG ACTTCAGCCC CTTTGACTTT GCCCACTTTG GATTTCCTTC 1200
TGATAATTCA GGTAAAGAAC GCAβTTTCCA GGCAAAGCCT TCTCCAAAAC TGGGGCGTCA 1260
TGTCTACTCC AGGCCCAAGG TTGATATTCA GAAAATCTGC ATAβGAAACA AGAACATCTT 1320
CACCGTCTCT GATCTGAAAC CCGACACGCA GTACTACTTT GACGTATTTG TGGTCAACAT 1380
CAACAGCAAC ATGAGCACCG CTTATβTAβG TACCTTTGCC AβGACCAAGG AAGAAGCCAA 1440
ACAGAAGACA GTCGAGCTCA AAGATGGGAA GATAACAGAT GTATTTGTTA AAAGGAAGββ 1500
AGCAAAGTTT CTACGGTTTG CTCCAGTCTC TTCTCACCAA AAAGTCACCT TCTTTATTCA 1560
CTCTTGTCTG GATGCTGTCC AAATCCAAGT GAGAAGAGAT GGGAAACTTC TTCTGTCTCA 1620
GAATβTββAA GGCATTCAGC AGTTTCAGCT TAGAGβAAAA CCTAAAGCTA AATACCTCGT 1680
TCGACTGAAA GGAAACAAGA AAGGAβCATC TATGTTGAAA ATTCTAGCTA CCACAAGGCC 1740
TACTAAGCAG TCATTTCCCT CTCTTCCTGA AGACACAAGA ATCAAACCCT TTGACAACCT 1800
CCGTACCTGT TCCTCGGCCA CCGTGβCTTG CCTAGGCACT CAGβAAAGGA ACAAGTTTTG 1860
CATCTACAAA AAAGAAGTGG ATGATAACTA CAATGAAGAC CAGAAGAAAA GAGAGCAAAA 1920
CCAATCTCTA GGACCAGATA TAAGGAAGAA GTCAGAAAAG GTCCTCTGTA AATATTTCCA 1980
GAGTCAAAAC CTGCAGAAAG CAGTGACCAC AGAAACAATT AAAGGTCTTC AGCCTGGCAA 2040
ATCTTACCTG CTGβATGTTT ATGTCATAGG ACATββGGββ CACTCTGTAA AGTATCAGAG 2100
TAAGGTTGTG AAAACTAGAA AGTTCTGTTA GTTACCTTCT TATAGAGATA TATTATGTAG 2160
AACTCCAGGA GGGACATTAA ATCACTTTAA GTATAAACTG ACTACTCCCA CAGTTGAGAG 2220
AAGTTGTGAC CTGTACTTGT ACTATGGAAG GAAGGATATC AACGTGTGTA TATTGATGTT 2280
TATATAAGTA ACTCTTGAAG GAGACTTGTT CTAGCGTGCC CCATGGTACC TAGTGTGTGT 2340
CTGATGCCGG TTGGT6TCAA AGATAGAGGG CTTCTTGAAG GAACTTGCCA TTCCTTGCTT 2400
TGACCACTGC ATβAACTGCT TCTAAATTAT TTTATTACCT AAAAATTTAA AATATGCCAT 2460
TCATTGCACA CACCCACAAA TGCAAATCAT TCCTCTCTAT AGATGCTAGG ATATATATAA 2520
ATTATTTTAT AAATTCTTGT TTTAAATGTC AβTβTTTCTA TGATTGTAAA CTATTAAATT 2580
CTTTTCCTAT TAAAGTACAG ATCTAATCTA AβTATTATTA AGTTGATAGC CCTCTAGTCA 2640
GTTATATTGC TATTGTAAAT TCTTGTTTGT TβAβTAAAAT GTTTAAATAC TATATGTATC 2700
TCATGTACAA AGTTGACATA CATTATATTC ATβTACATAA AATTAAAGAG ATTAGATTAT 2760
ATACTGTTAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAA 2808
Seq ID NO: C56 DNA Sequence Nucleic Acid Accession #: BC034229.1 Coding sequence: 373..1422
1 11 21 31 41 51 1 1 I 1 I 1 I 1 | 1 | 1 ATCCGGCGGT GGTGACGCGA GAGGCTGGGG TCTCCAGGAC CAACTCCTCT TCATCTTCCT 60
CTTCCTCAGC CTGCTCAATG TGAAGCCCCT GATCATGATT CACTTCCACT TAATAAATAA 120
AGTGTTTACA AATCAGAATA ACTTTTAGAC AATATTAAGG TGGTAATCAT GAACAGAAAA 180
GATTTTGTAG TTCTTCCATG GGGAAAACCT GGAAATTCTG TAAAGCTAAA ATATAGCAAT 240
GTAATAATTA AAACAAAAGT CTAAGATTTG AAGAGATAAT TTGCTTCAGG ATTTTβATGG 300
AAGGCAAATG CTAACTTTAA AAACCAGATT TCGGAGAAGT ACAAAAGAAA TAGAAATGCT 360
CAAGAACTGC GAATGGAGAA AGTACAGTTA GAGTTTGAGA ACCAAGAGAT ββAGAAGAAA 420
CTGCAAGAAT TCCGATCCAC AAGAAACAAA GAAAAGGAAG ATAGAGAGTC AAGCGAGTAT 480
TACTGGAAAT CTGGAAAAGT GGGCAAATTG GTCAATCAAT CATATATGAT GTCACAAAAT 540
AAAGGAAATG TTGTTAAGTT TTCTGCTGGA AAAGTGAAAT TAAAATTGCT GAAGGAACAG 600
ATTCAAGAGC CAGTGAAACC AACAGTTAAT TATAAAATGG CAAATTCTTC AGAATGTβAA 660
AAACCCAAGA TAAATGGGAA AGTTTGTβGA CAGTGTGAGA ACAAAGCTGC TCTACTGGTA 720
TGCCTTGAAT GTGGAGAAGA TTATTGTTCA G6ATGCTTTG CTAATCTTCA CCAGAAAG6G 780
GCACTAAAGC TCCACAGAAC AACTCTTTTG CAGGCAAGAT CTCAAATATT ATTCAATGTA 840
TTGGATβTTG CCCATCAGTT TATAAAGGAT GTTAATCCAG ATGAACCCAA AGAGGAβAAT 900
AATTCTACAA AGGAAACCAG TAAAATTCAA CATAAACCCA AATCTGTACT TCTCCACAGG 960
AGCAGCTCTG AGGTAGAAAT TACAACGATG AAAAGAGCAC AACGTACAAA ACCAAGAAAG 1020
AGTCTGTTGT GTGAAGGGTC ATTCGATGAA 6AAGCTTCTG CACAβTCCTT TCAGGAAGTG 1080
TTAAGTCAAT GGAGAACCGG AAATCATGAT GACAACAAGA AACAGAATTT ACATGCAGCA 1140
GTAAAAGACT CATTGGAAGA ATGCGAAGTA CAGACTAATC TGAAAATTTG GAGAGAACCA 1200
CTTAATATTG AACTTAAAGA AGACATTCTA TCCTATATGG AAAAATTATG GCTTAAAAAA 1260
CACAGGAGAA CTCCACAAGA GCAACTTTTT AAATβCTACC AGATACβTTC CCACATCCAC 1320
ATGAAACCAC TGGTGATGCA CAGTGTTCTC AAAATGAAAA CβATβAAGAT AGTGATGβTβ 1380
AGGAGACCAA AGTACAACAC ACAGCTCTTT TATTGCCAGT AGAAACATTA AACATAGAGA 1440
GACCTβAACC ATCTCTGAAG ATAGTCGAAC TGGATGATAC TTATGAAGAG GAATTTGAAG 1500
AAGCAGAAAA TATTGTGCCT TACAAAGTTA AATTAGCTGA TGCAGACAGT CAACGAAGTT 1560
GTβCTTTTCA TGATTGTCAG AAGAATAGCT TTCCATATGA AAATGGCATC CATCAACATC 1620
ATGTTTTCGA TAAGGβAAAβ AGAGACTTCT TAAATCTTTG TCTGAGAAAC A6CTCTACTT 1680
ATTATAAAGA TAATTCAAAA GGAGAAACTT CAAACACAGA TTTTGACAAC ATCGTGGATC 1740
CTGATβTGTA TTCTTCTGAC ATTβAAAAAA TTGAGGAAAG CACCTCCTTT GAAAGAAATT 1800
TAAAGGAGAA AAATATAGGT TTAβAAAβTA ATCAAAAGTC TGATGATTCC TGTGTATCAC 1860 TTGAAAGCAA GGACACTTTG CTAGGTAGAG ATTTAGAAAA AGCTCCCATT GAGGAGAAAT 1920 TATCTCAAGA CATCAAAGAA TCCTTGGAAT TGAβCAATCT GTATAAGAGG CCAAGCTTTG 1980 AAGAATCAAA AACTACAAAG TCATCACTβT TGTTACAAGA AATAGCCTGC AβAAGTAAGC 2040 CTATAACAAA ACAATATCAA GGACTTGAGA GATTCTTTAT TTTTGATACA AATGAAAGAC 2100 TCAACTTACT TCCTTCTCAT CGTTTAGAAT eCAACAATTC CAGTACTAGG ATTACACTTG 2160 CAGGTCAGAA ATCACAGAGA CCTTCAACAG CAAATTTTCC ACTTTCCAAC TCTGTTAAAG 2220 AAAGCTCCAG TTGCCTTTCA TCCTCTCATC CTCβATCAAβ AAGTGCAGCT GCTCAATCAT 2280 CATCTAGAβC TGCTTCTGAA ATTTCAGAAA TTGAATATAT TGATATTACT GACCAGAATG 2340 AGCTTTCCTT AGATGACACT ACTGATCAAC ATACTTTAGA CAATTTGGAA AAAGAATTAC 2400 AAGTGCTGAG ATCTCTTGCA GATACTTCAG AAAAGCTTTA CAGCTTAACC TCAGAAGAGT 2460 TCCCAGATTT CAGCAGCCAA TCACTGAATA TAAβTCAβAT TTCCACAGAT TTCCTTAAGA 2520 CCTCACATGT GAGGGβTCCC TGTGGAGTTG AGGAATTGAG CTGTTCTGGA AGAGATACCA 2580 AAATTCAβTC TTTGCTGTCA CTTTCTCAβA GCAGTACAGA TGAGGAGGAG GAAGATTTTC 2640 TCAACAAGCA ACATGTCATC ACACTACCβT GGTCAAAGAG TACTTAAAGA TTATTTGTTC 2700 ATTACTGTTT CCATTTTGTA CCCAGAGTAA AGCAAACAAC TGAGAAAAGT AACCAAGTGA 2760 TTACCTATCC AAGTGCTGGA GATTTTGATT ACTAATGTCT TTGATGTTTC AAGGCTACAA 2820 ACTAATAAAA GTAAAATTAT AAGTTCAAAA AAATTTTTAA AAAAAAAAAT AAAAAA 2876 Seq ID NO: C57 DNA Sequence
Nucleic Acid Accession ft: NM.024687.1 Coding sequence: 138..1706
11 21 31 41 51
I I I I
AAAAACATGA TGACAACAAG AAACAGAATT TACATGCAGC AGTAAAAGAC TCATTGGAAG 60 AATGCGAAβT ACAGACTAAT CTGAAAATTT GGAGAGAACC ACTTAATATT GAACTTAAAG 120 AAGACATTCT ATCCTATATG GAAAAATTAT GGCTTAAAAA ACACAGGAGA ACTCCACAAG 180 AGCAACTTTT TAAAATGCTA TCAGATACGT TCCCACATCC ACATGAAACC ACTGGTGATG 240 CACAGTGTTC TCAAAATGAA AACCATβAAG ATAGTGATGG TGAGGAGACC AAAGTACAAC 300 ACACAGCTCT TTTATTGCCA GTAGAAACAT TAAACATAGA GAGACCTGAA CCATCTCTGA 360 AGATAGTCGA ACTGGATGAT ACTTATGAAG AGGAATTTGA AGAAGCAGAA AATATTGTGC 420 CTTACAAAGT TAAATTAGCT GATGCAGACA GTCAACGAAG TTGTGCTTTT CATGATTβTC 480 AGAAGAATAG CTTTCCATAT GAAAATGGCA TCCATCAACA TCATGTTTTC GATAAGGGAA 540 AβAGAβACTT CTTAAATCTT TGTCTGAGAA ACAGCTCTAC TTATTATAAA GATAATTCAA 600 AAGGAGAAAC TTCAAACACA GATTTTGACA ACATCGTGβA TCCTGATGTG TATTCTTCTG 660 ACATTGAAAA AATTGAGGAA AGCACCTCCT TTGAAAGAAA TTTAAAGGAG AAAAATATAG 720 GTTTAGAAAG TAATCAAAAG TCTGATGATT CCTGTGTATC ACTTGAAAGC AAGGACACTT 780 TGCTAGGTAG AGATTTAGAA AAAGCTCCCA TTGAGGAGAA ATTATCTCAA GACATCAAAG 840 AATCCTTGGA ATTGAGCAAT CTGTATAAGA GGCCAAGCTT TGAAGAATCA AAAACTACAA 900 AGTCATCACT GTTGTTACAA GAAATAGCCT GCAGAAGTAA GCCTATAACA AAACAATATC 960 AAGGACTTGA GAGATTCTTT ATTTTTGATA CAAATβAAAG ACTCAACTTA CTTCCTTCTC 1020 ATCGTTTACA ATGCAACAAT TCCAGTACTA GGATTACACT TGCAGAAGAC AGAGAATGGA 1080 TTCCAGACCA TAGCTTAAGT GAATATβCTG ATAATGCAAT TGTCTTGGGT GTTCTGCAGG 1140 GTGCTCAGAG TCCATCATCA AGTAGAAAAC AGCAAAAGAT GGGTCAGAAA TCACAGAGAC 1200 CTTCAACAGC AAATTTTCCA CTTTCCAACT CTGTTAAAGA AAGCTCCAGT TGCCTTTCAT 1260 CCTCTCATCC TCGATCAAGA AGTGCAGCTG CTCAATCATC ATCTAGAGCT GCTTCTGAAA 1320 TTTCAGAAAT TGAATATATT GATATTACTG ACCAGAATGA GCTTTCCTTA GATGACACTA 1380 CTGATCAACA TACTTTAGAC AATTTGGAAA AAGAATTACA AGTGCTGAGA TCTCTTGCAG 1440 ATACTTCAGA AAAGCTTTAC AGCTTAACCT CAGAAGAGTT CCCAGATTTC AGCAGCCAAT 1500 CACTGAATAT AAGTCAβATT TCCACAGATT TCCTTAAGAC CTCACATGTG AGGGGTCCCT 1560 GTGGAGTTGA GGAATTGAGC TGTTCTGGAA GAGATACCAA AATTCAGTCT TTGCTGTCAC 1620 TTTCTGAGAG CAGTACAGAT GAGGAGGAGG AAGATTTTCT CAACAAGCAA CATGTCATCA 1680 CACTACCGTG GTCAAAGAGT ACTTAAAGAT TATTTGTTCA TTACTGTTTC CATTTTGTAC 1740 CCAGAGTAAA GCAAACAACT GAGAAAAGTA ACCAAGTGAT TACCTATCCA AGTGCTGGAG 1800 ATTTTGATTA CTAATGTCTT TGATGTTTCA AGGCTACAAA CTAATAAAAG TAAAATTATA 1860 AGTTCAAAAA AAAAAAAAAA AAAA 1884
Seq ID NO: C58 DNA Sequence
Nucleic Acid Accession #: NM_005408.1
Coding sequence: 76.-372
11 21 31
AAAAGGCCGG CGGAACAGCC AGAGGAGCAG AGAGGCAAAG AAACATTGTG AAATCTCCAA 60
CTCTTAACCT TCAACATGAA AGTCTCTGCA GTGCTTCTGT GCCTGCTGCT CATGACAGCA 120
GCTTTCAACC CCCAGGGACT TGCTCAGCCA GATGCACTCA ACGTCCCATC TACTTGCTGC 180
TTCACATTTA GCAGTAAGAA GATCTCCTTG CAGAGGCTGA AGAGCTATGT GATCACCACC 240
AGCAGGTGTC CCCAGAAGGC TGTCATCTTC AGAACCAAAC TGGGCAAGGA GATCTGTGCT 300
GACCCAAAGG AGAAGTGGGT CCAGAATTAT ATGAAACACC TGGGCCGGAA AGCTCACACC 360
CTGAAGACTT GAACTCTGCT ACCCCTACTG AAATCAAGCT GGAGTACGTG AAATGACTTT 420
TCCATTCTCC TCTGGCCTCC TCTTCTATβC TTTGGAATAC TTCTACCATA ATTTTCAAAT 480
AGGATGCATT CGGTTTTGTG ATTCAAAATG TACTATGTGT TAAGTAATAT TGGCTATTAT 540
TTGACTTGTT GCTGGTTTGG AGTTTATTTG AGTATTGCTβ ATCTTTTCTA AAGCAAGGCC 600
TTGAGCAAGT AGGTTGCTGT CTCTAAGCCC CCTTCCCTTC CACTATGAGC TGCTGGCAGT 660
GGGTTTβTAT TCGGTTCCCA GGβGTTGAβA GCATGCCTGT GGGAGTCATG GACATGAAGG 720
GATGCTGCAA TGTAGGAAGG AGAGCTCTTT GTGAATGTGA GGTGTTGCTA AATATGTTAT 780
TGTGGAAAGA TGAATGCAAT AGTAGGACTG CTGACATTTT GCAGAAAATA CATTTTATTT 840
AAAATCTCCA AAAAAAAAAA 860
Seq ID NO: C59 DNA Sequence
Nucleic Acid Accesεion #-. AK097746.1
Coding sequence: 185..2224 1 11 21 31 41 51
1 1 I 1 I 1 | 1 1 1 CTTTCATGAC AGTAACAAAT CCAACATTTT GGAAAAGCGC CTACGATATT TAAATGACCA 60
CTTCACATAC AACTTATATT GTAATATATG CCGATCACTA TTTGAGAAGG ACAAGCTGTT 120
ATTTTCCTTT TTATTATGTG CCAATCTTCT TCTGGCAAGG AAAGAGATTβ AATACCAGβA 180
ACTGATGTTT CTTTTAACTG GAGβAGTAAG TCTTAAAAGT GCTGAGAAAA ATCCTGATCC 240
AACTTGGCTA CAGGACAAAA GCTCβGAGGA AATCTGTCGG GCAAGTGAAT TTCCTGCCTT 300
CAGAGGACTC AGGCAACATT TTTGTGAACA TATATATGAA TGGCGAGAAA TCTATβACAG 360
TAAAGAGCCA CATAATGCTA AATTTCCAGC ACCAATGGAT AAGAACCTAA ATGAACTACA 420
GAAAATAATA ATTCTTCGGT GTTTAAGACC TGATAAGATA ACCCCAGCTA TAACAAACTA 480
TGTAACTGAC AAACTAGGGA AAAAGTTTGT AGAGCCTCCA CCATTTGATT TGACAAAGAG 540
TTACTTGGAT TCAAATTGCA CCATTCCCTT AATTTTTGTT CTATCTCCAG GAGCAGATCC 600
TATGGCCAGC CTGCTGAAAT TTGCAAATGA TAAATCTATG TCTG6AAATA AGTTTCAAGC 660
TATTTCACTG GGACAGGGAC AAββACCβAT TGCACCAAAA ATGATTAAAG CAGCAATTGA 720
AGAAGGAACT TGGGTGTGCC TACAGAATTG CCATCTTGCA GTGTCCTGGA TGCCCATGTT 780
GGAAAAAATA TGTGAAGATT TTACCTCTGA AACCTGTAAC TCATCCTTTA GGCTTTGGCT 840
GACAAGCTAT CCATCTTCAA AATTCCCAβT AAGAATTCTA CAGAATβGAG TAAAAATGAC 900
TAATGAACCT CCCACGGGTC TTCGGCTGAA TCTCCTTCAA TCATATCTCA CTGATCCAGT 960
TTCTGATCCT GAGTTTTTCA AGGGATGCCG TGGAAAGβAA CTGTTATTTA TCAATGAATA 1020
TGATACAATT CCATTTGAAG CTATATCTTA CCTβACTββG GAGTGTAATT ATGGAGβAAβ 1080
AGTGACAGAC GATTGGGACA GACGTCTTCT ATTAACCATG CTGGCTGACT TTTATAATCT 1140
GTACATAβTT GAAAACCCTC ATTATAAGTT TTCTCCCAGT GGAAACTATT TTGCACCTCC 1200
TAAAGGCACT TATGAGGACT ACATTGAATT CATTAAGAAA CTTCCATTTA CTCAACACCC 1260
TGAGATATTT GGATTACATG AAAACGTTGA CATCTCCAAG GATCTTCAAC AAACAAAAAC 1320
CCTCTTTGAG TCCTTGCTCC TCACCCAGGG AGGCTCCAAA CAGACAGGAβ CCTCAGGAAG 1380
TACTGATCAβ ATTCTGTTAβ AAATTACCAA AGATATCCTC AACAAGCTCC CTAGTGATTT 1440
CGACATTGAA ATGGCACTAC GGAAGTATCC TGTGAGATAT GAAGAAAGCA TGAATACTGT 1500
GTTAGTACAA GAAATGGAAA GATTTAACAA TTTAATTATA ACTATACGTA ACACTCTACG 1560
GGACCTTGAA AAAGCTATTA AGGGTGTGGT TGTβATββAT TCTGCATTGG AGGCACTCTC 1620
CAGTAGCTTA CTTGTTGGAA AGGTTCCAGA AATATβGGCC AAACGTTCAT ACCCAAGCCT 1680
TAAGCCCCTG GGAAGTTACA TCACAGATTT CCTAGCCCGG TTGAACTTTT TACAGGACTG 1740
GTATAATTCA GGAAAACCTT GTGTGTTTTG GCTGTCAGβT TTCTTTTTCA CTCAGGCCTT 1800
TTTAACTGGA GCTATGCAGA ATTATGCCAG AAAATATACC ACCCCTATTG ATTTGCTAGG 1860
ATATGAATTT GAGGTTATCC CATCTGATAC ATCTGACACA TCACCAGAAG ATGGTGTTTA 1920
TATCCACGGA CTGTATCTCG ATGGCGCACG CTGGGACCGA GAAAGTGGAT TGCTTGCTGA 1980
ACAATATCCC AAACTTCTGT TTGACCTGAT GCCCATCATA TGGATAAAAC CAACTCAAAA 2040
ATCTCGGATT ATAAAGTCGβ ATGCCTATGT CTGTCCCCTC TACAAGACAA GTGAACGTAA 2100
AGGAACTCTT TCCACTACββ GACATTCTAC TAACTTTGTC ATTGCAATGT TGTTAAAAAC 2160
AGACCAACCT ACTceβCACT GGATCAAGCG CGGGGTTGCT TTGCTTTGTC AGTTGGATGA 2220
CTAAATTGβA CAAATTTATA AAACATCCAA AAGTTT 2256
Seq ID NO: C60 DNA Sequence Nucleic Acid Accession #: J02761. Coding sequence: 14..1159
1 11 21 31 41 51 1 1 | 1 J 1 | 1 | 1 | 1 GAATTCCGGT GCCATGGCTG AGTCACACCT GCTGCAGTβG CTGCTGCTGC TGCTGCCCAC 60
GCTCTGTGGC CCAGGCACTG CTGCCTGGAC CACCTCATCC TTGGCCTGTG CCCAGGGCCC 120
TGAGTTCTGG TGCCAAAGCC TGGAGCAAGC ATTGCAGTGC AGAGCCCTAG GGCATTGCCT 180
ACAGGAAGTC TGGGGACATG TGGGAGCCGA TGACCTATβC CAAGAGTGTG AGGACATCGT 240
CCACATCCTT AACAAGATββ CCAAGGAGGC CATTTTCCAG GACACGATGA GGAAGTTCCT 300
GGAGCAGGAG TGCAACGTCC TCCCCTTGAA GCTGCTCATG CCCCAGTGCA ACCAAGTGCT 360
TGACGACTAC TTCCCCCTGβ TCATCGACTA CTTCCAGAAC CAGACTGACT CAAACGGCAT 420
CTGTATGCAC CTGGβCCTGT GCAAATCCCG GCAGCCAGAG CCAβAβCAGG AGCCAGGGAT 480
GTCAGACCCC CTGCCCAAAC CTCTGCGGGA CCCTCTGCCA GACCCTCTGC TGGACAAGCT 540
CGTCCTCCCT GTGCTGCCCG GββCCCTCCA GGCGAGβCCT GGGCCTCACA CACAGβATCT 600
CTCCGAGCAG CAATTCCCCA TTCCTCTCCC CTATTGCTGG CTCTGCAGGG CTCTGATCAA 660
GCGGATCCAA GCCATGATTC CCAAGGGTGC GCTAGCTGTG GCAGTGGCCC AGGTGTGCCG 720
CGTGGTACCT CTGGTGGCGG GCGGCATCTG CCAGTGCCTG GCTGAGCGCT ACTCCGTCAT 780
CCTGCTCGAC ACGCTGCTGG GCCGCATGCT GCCCCAGCTG GTCTGCCGCC TCGTCCTCCG 840
GTβCTCCATG GATGACAGCG CTGGCCCAAG GTCGCCGACA GGAGAATGGC TGCC6CGAGA 900
CTCTGAGTGC CACCTCTGCA TGTCCGTGAC CACCCAGβCC GGGAACAGCA GCGAGCAGGC 960
CATACCACAG GCAATGCTCC AGGCCTGTGT TGGCTCCTGG CTGGACAGGG AAAAGTGCAA 1020
GCAATTTβTβ GAGCAGCACA CGCCCCAGCT GCTGACCCTG GTGCCCAGGG GCTββGATGC 1080
CCACACCACC TGCCAGGCCC TCββGCTCTG TG6GACCATG TCCAGCCCTC TCCAGTβTAT 1140
CCACAGCCCC GACCTTTGAT GAGAACTCAG CTGTCCAGCT GCAAAGGAAA AGCCAAβTβA 1200
GACGGGCTCT GGGACCATGG TGACCAGGCT CTTCCCCTGC TCCCTGGCCC TCGCCAGCTG 1260
CCAGGCTGAA AAGAAGCCTC AβCTCCCACA CCGCCCTCCT CACCTCCCTT CCTCGGCAGT 1320
CACTTCCACT GGTGGACCAC GGGCCCCCAG CCCTGTGTCG GCCTTGTCTG TCTCAGCTCA 1380
ACCACAGTCT GACACCAGAG CCCACTTCCA TCCTCTCTGG TGTGAGGCAC AGCGAGGGCA 1440
GCATCTGGAG GAβCTCTGCA GCCTCCACAC CTACCACGAC CTCCCAGGGC TGGGCTCAGG 1500
AAAAACCAGC CACTGCTTTA CAGGACAGGG GGTTGAAGCT GAGCCCCGCC TCACACCCAC 1560
CCCCATGCAC TCAAAGATTG GATTTTACAG CTACTTGCAA TTCAAAATTG AGAAGAATAA 1620
AAAATGGGAA CATACAGAAC TCTAAAAGAT AGACATCAGA AATTGTTAAG TTAAGCTTTT 1680
TCAAAAAATC AGCAATTCCC CAGCGTAβTC AAGGGTGGAC ACTGCACGCT CTGGCATGAT 1740
GGGATβGCGA CCGGGCAAGC TTTCTTCCTC GAβATGCTCT GCTGCTTGAG AGCTATTGCT 1800
TTGTTAAGAT ATAAAAAGGG GTTTCTTTTT GTCTTTCTGT AAGβTGGACT TCCAGATTTT 1860
GATTβAAAGT CCTAGGGTGA TTCTATTTCT GCTGTGATTT ATCTGCTGAA AGCTCAGCTG 1920
GGGTTβTβCA AGCTAGGGAC CCATTCCTGT GTAATACAAT GTCTGCACCA ATGCTAATAA 1980
AGTCCTATTC TCTTTTAAAA AAAAAAAAAA AAAAAAAACG βAATTC 2026
Seq ID NO : C61 DNA Sequence Nucleic Acid Accession ft: NM_139172.1 Coding sequence: 19..552
GGGGTCTGGG βAGGTGACAT GTTGGGCTGT GGGATCCCAG CGCTG6GCCT GCTCCTGCTG 60
CTGCAGGGCT CGGCAGACGG AAATGGAATC CAGGGATTCT TCTACCCATG GAGCTGTGAG 120
GGTGACATAT GGGACCGGGA GAGCTGTGGG GβCCAGGCGβ CCATCGATAG CCCCAACCTC 180
TGCCTGCGTC TCCGGTGCTG CTACCGCAAT eeββTCTGCT ACCACCAGCG TCCAGACβAA 240
AACGTGCGGA GGAAGCACAT GTGGGCGCTG GTCTGGACGT GCAGCGGCCT CCTCCTCCTG 300
AGCTGCAβCA TCTGCTTGTT CTGGTGGGCC AAGCGCCGGβ ACGTGCTGCA TATGCCCGGT 360
TTCCTGGCCβ GTCCGTGTGA CATGTCCAAG TCCGTCTCGC TGCTCTCCAA GCACCGAGGG 420
ACCAAβAAGA CGCCGTCCAC GGGCAGCGTG CCAGTCGCCC TGTCCAAAGA GTCCAGGGAT 480
GTGGAGGGAβ GCACCβAGGG GGAAGGGACG GAβGAGGGTβ AGGAGACAGA GβGCGAGGAA 540 βAGGAGGATT AGGGGAGTCC CCGGGGGACT βCTCAATACA GATACGGTGG ACG 593
Seq ID NO: C62 DNA Sequence
Nucleic Acid Accession #: NM_054023.2
Coding sequence: 98..379
1 11 21 31 41 51 1 1 | 1 | 1 I 1 1 1 | 1 GGGGACACTT TGTATGGCAA GTGGAACCAC TGGCTTGGTG GATTTTGCTA GATTTTTCTG 60
ATTTTTAAAC TCCTGAAAAA TATCCCAGAT AACTGTCATG AAGCTGGTAA CTATCTTCCT 120
GCTGGTGACC ATCAGCCTTT GTAGTTACTC TGCTACTGCC TTCCTCATCA ACAAAGTGCC 180
CCTTCCTGTT GACAAGTTββ CACCTTTACC TCTGGACAAC ATTCTTCCCT TTATGGATCC 240
ATTAAAGCTT CTTCTβAAAA CTCTGGGCAT TTCTGTTGAG CACCTTGTGG AGGGGCTAAG 300
GAAβTGTGTA AATGAGCTGG GACCAGAGGC TTCTGAAGCT GTGAAGAAAC TGCTGGAGGC 360
GCTATCACAC TTGGTGTGAC ATCAAGATAA AGAGCGGAGβ TGGATGGGGA TGGAAGATGA 420
TGCTCCTATC CTGCCTGCCT βAAACCTβTT CTACCAATTA TAGATCAAAT GCCCTAAAAT 480
GTAGTGACCC GTGAAAAGGA CAAATAAAGC AATGAATACT AAAAAAAAAA AAAAAAAAAA 540
AAAAAAAAAA 550
Seq ID NO: C63 DNA Sequence Nucleic Acid Accession #: FGENESH predicted Coding sequence: 1..2874
11 21 31
ATGCCCCTGT CCTATGCCTA TAAAAACGCT GAGACCCTAG CAGGCAGACA CACAAGCAGC 60
TGGATGTCGA GAGGAGCATA TCAGCGGAGG AACACACGGβ CAGCTGGACG TCCAGAGGAA 120
TGCACTGACA GAAACTGGCA TGCTGGCAGA ACACGTGβAA TTTGGCTGGG GCAGTTGGAG 180
GAGAGATGTT CAGATGTGTT CββAβTTTCT TTCTTCTGβT GGGTTCGTGG TCTCGCTGGC 240
TCAGGAGCGA AGCTGCAGAC CTTCACGCCA GCCCAGGAA6 GGGCTCCCAC AGTGCAGCGG 300
CAGGCTGAAG CGCTCCTCAA GTGCCGCCAG AGTβGGCGTC CAGGCAGAGG AGβCGCCGAG 360
AGCGAGCGAG CGAGGGATGC CAGCATGCTG TCACCTCTCA GTβCTGCCAT GCβAAACTAC 420
CCAACGTCCT CTACCATCCC TCCAAGAAGA TCCTACTCTC CAACCGAAAT TGCTCACAAG 480
AGTTACTCCT GCAGCCTTCC AGACATGAAA ATCTCCATGβ CAGAATCTGβ CCCCTCCTTG 540
GATAGCCTTG ACATTCTGGA βGATGGCGAG TCTGGGTCAC CATTTCTTGT GACTCATTTG 600
TACTTTCTGG GG6TTGTCAC CACTGββATG GAACAACTAG ATTTTGAAAC AGGACCAAAC 660
ATATTTGATT TGCA6ATTTA TGTGAAGGAT GAGGTTGGTG TCACAGACCT GCAAGTCCTG 720
ACTGTCCAGG TAACAGATGT GAACGAGCCA CCTCAGTTTC AAGGCAACTT GGCAGAA6AT 780
CATCTCCGTG CAGACCAGCC ACATTTCAAT GCTCATAGTC ACACGTACGT GAGGGTAGTβ 840
GCTACTGCAT TGGCCAGGCA CAGGCTTAGA TCTAGCATTG GTTCCCCCTT CCTGGβCACC 900
TTCTGTGTTG TGGTGGGCAT GCAGTATTTC CTGATTTCTC CCCCAAAGAG CTTCAGAATG 960
TCTGCTAATG GCACCCTCTT CTCCACAACA GAATTGGACT TTGAAGCAGβ ACACAGAAGT 1020
TTCCATCTCA TCGTGGAGGT GAGGGACAGT GGAGGCCTCA AAGCCTCCAC AGAGCTCCAG 1080
GTGAACATCG TGAACCTCAA CGACβAAβTC CCTCGCTTTA CCAGCCCGAC ACGAGTGTAC 1140
ACAGTCCTGG AGGAACTGAG TCCAβGAACC ATCGTGGCCA ATATCACAGC GGAGGATCCT 1200
GATGATGAAG GTTTTCCCAβ CCACCTCCTC TACAGCATTA CCACTGTTAG CAAATATTTC 1260
ATGATAAATC AGTTGACTGG TACAATCCAA GTGGCCCAAA GGATAGACCG AGATGCAGGT 1320
GAATTGAGAC AAAATCCCAC CATTTCCCTG GAAGTTCTAG TGAAGGACAG ACCATATGβG 1380
GGTCAGGAGA ATCGCATCCA GATAACCTTC ATTGTGGAAG ACGTCAACGA CAATCCTGCC 1440
ACATGCCAAA AGTTCACCTT CAGATCCAGT CTCCACCCTG CTCTGTGCTC CAAGACGCTG 1500
ACCTGGATGG ATACCGTATT AGACTGTTTT CATGCTGCTG ATAAAGATAT ACCTGTGACT 1560
GGGCGATTTA CAAAAGAAAG AGGTTTAATT GGACTTACAG TTCCACATGG CTGGGGAAGC 1620
CTCACAATCA TGGCAGAAGG CAAGGAGGAG CAAGTCACAT CTTACATGGA TGGCAGCAGG 1680
CAAAGAGATA GAGCTTGTGT AGβGAAACTC CTCCTTATAA AGCCATCAGA TCTCATGAGA 1740
CTTAGTCACT ATCACGAGAA CAACTCAGGA AAGACTTGCC CCCATGATTC CATTTCCTCC 1800
TACCAGβTCC CTCCCACAAC ATGTAGGAAT TCAAβAATCC AGGCCACCAA CAACGAAGAC 1860
ACAAGCTCT6 TCACTGTTAC TGTGAACATC CTTGAAGAAA ATGATGAAAA GCCAATTTGT 1920
ACTCCAAACT CTTATTTCCT GGCCCTCCCA GTββATCTGA AAGTTGGCAC AAATATTCAG 1980
AATTTCAAGC TGACATGTAC CGACCTTGAT TCCAGCCCCA GATCTTTCCG TTATTCCATT 2040
GGCCCAGGTA ACGTCAACAA TCATTTCACC TTCTCTCCCA ATβCTGGTTC CAATGTCACA 2100
CGCCTGCTGC TTACATCTCG CTTTGACTAT GCTGGTGGGT TTGATAAGAT CTGGβACTAC 2160
AAGCTACTTG TCTACGTAAC TβATGACAAC TTGATGTCTG ACAGGAAGAA AGCβGAGGCT 2220
CTTGTTGAGA CAGGAACAGT GACACTGAGT ATTAAAGTCA TTCCCCACCC AACCACTATC 2280
ATCACCACGA CCCCCAGGCC CAGGGTCACC TATCAGGTCC TGAGGAAAAA CGTTTACTCT 2340
CCATCTGCAT GGTACGTβCC GTTTGTCATC ACTTTGGGCT CCATATTGCT TCTGGGTCTC 2400
CTCGTGTACC TGGTCGTCCT ATTGGCCAAA GCCATCCACA GACACTGCCC CTGCAAGACT 2460
GββAAGAACA AGGAACCTCT GACAAAGAAA GGAGAAACGA AGACTGCAGA GAGAGACGTC 2520
GTGGTβGAAA CTATCCAGAT GAACACTATC TTTGATGGAG AAβCCATACA TCCAGAGCCT 2580
GAGCAACCTT CACTCGAGCT CTATGCCCTG CTGCCCAGCT GCTGCGACCC TAGTCCAGTA 2640
ACCCTAAGAA AGGTCCAGGT GTGTGGGGAG AGTGAAGAGA CCGGTCAGTG TTCCGGCCAC 2700 ATCACACTTC CCGGCAAGAT TCCAGTCGAT GACCCAAGGA AACAGGAAAC AGGCCTGCAG 2760 GGTGATTTCG AGGTCTGGAC TCTATGCCCC GCTGTGAAGG TGGTTGTAGG CAGCCCTCAA 2820 GCTGAACGGT GCATTCGATT βGCTCTCAGT CTGAAAAAβT ACAGTTCTGA TTAA 2874
Seq ID NO: C64 DNA Sequence
Nucleic Acid Accession ft: XM_168571.1
Coding sequence: 155..988 '
1 11 21 31 41 51
1 1 1 | 1 1 1 | 1 | 1 TACACAGTCC TGGAGGAACT GAGTCCAGGA ACCATCGTGG CCAATATCAC AGCGGAGβAT 60
CCTGATGATG AAGGTTTTCC CAGCCACCTC CTCTACAGCA TTACCACTGT TAGCAAATAT 120
TTCATGATAft. ATCAGTTGAC TGGTACAATC CAAGTGGCCC AAAGGATAGA CCGAGATGCA 180
GGTGAATTGA GACAAAATCC CACCATTTCC CTGGAAGTTC TAGTGAAGGA CAGACCATAT 240
GGGGGTCAGG AβAATCGCAT CCAGATAACC TTCATTGTGG AAGACGTCAA CGACAATCCT 300
GCCACATGCC AAAA6TTCAC CTTCAGCATT ATββTGCCGG AAAGAACAGC CAAGGGGACG 360
TTGCTTCTTG ACCTAAACAA GTTCTGCTTT GATGATGACA GTGAGGCACC AAACAACAGA 420
TTCAACTTCA CCATCCCATC TGGAGTGGGG AGCGGCAGCA GATTTTTACA GGATCCAGCT 480
GGCTCTGGGA AGATTGTGCT GATTGGTGAT CTAGACTACG AAAATCCAAG TAACCTAGCA 540
GCCGGCAATA AATATACGGT GATAATCCAG GTGCAGGATG TGGCCCCCCC TTACTATAAA 600
AATAACGTCT ACGTTTATAT CCTAACAAGC CCAGAAAATβ AGTTTCCTCT CATTTTTGAT 660
AGGCCATCCT ATGTATTTGA TGTGTCAGAA AGAAGGCCCG CCCAGGGTCA CCTATCAGGT 720
CCTGAGGAAA AACGTTTACT CTCCATCTGC ATGGTACGTG CCGTTTGTCA TCACTTTGGG 780
CTCCATATTG CTTCTβGGTC TCCTCGTGTA CCTGGTCGTC CTATTGGCCA AACCCATCCA 840
CAGACACTGC CCCTGCAAGA CTGGGAAGAA CAAGGAACCT CTGACAAAGA AAβGAGAAAC 900
GAAGACTGCA GAGAGAGACβ TCGTGGTGGA AACTATCCAG ATGAACACTA TCTTTGATGG 960
AGAAGCCATA GATCCAGTGA CCGGGβAAAC ATATGAATTC AACTCAAAAA CTGGAGCCAG 1020
AAAGTGGAAA GATCCACTAA CCCAAATβCC AAAATGGAAA GAGTCCAGCC ACCAGGGAGC 1080
TGCCCCACGC AGAGTCACTG CTGGGGAAGG GATGGG6TCA CTGAGAAGTG CCAACTGGGA 1140
AGAAGATGAG CTGAGTG6CA AAGCGTGGGC TGAGGATGCT GβTCTGGGTT CCAGAAATGA 1200
GGGTGGCAAG CTGGGCAACC CAAAGAACAG AAATCCAGCC TTCATGAACA GGGCTTACCC 1260
CAAACCACAC CCAGGAAAGT AAACGGGGTC TAAGGAGGGG CCTβTCAATC ACTGAGATGC 1320
TGCCTCACCC TAAATTCTAT GGGGATGGTG TGGGCATGGT GTAGGGGGGA AAATGTGGGC 1380
TGAGGGGATT CAGACATCCA GGGTCAAACA TGGGATGTTT GACAAATTTT TAAACAAATA 1440
GAAAβGGGTT TGATCACATA GTTGCGTGTT CTGAAATGAT ACAGGAACAT TTTCTATCAG 1500
ATTTCAGAAC TACCTGTGCT TCTGATAAGC AAGACTGTTA ACTTTGGGGT GTGGAATTGT 1560
TβTβTTTCTT CTTTCCATTG ACTGCTAGGA AGCTCTATTC T6TTCACCAT AGAAAGTTTG 1620
TAGGAATTCC TGACATAAAT AGTGAAGACT ATCCTTACAT CTGGTTTCCA CCTTATTTTC 1680
CTGCCCTCGT TTTAACATCA CCCAGATTTC TTCAGTTATA AATATGCCAT ACACCTTTGT 1740
AAGTCACCTC AAATCTTCTT CAAAAGAAGC AGAACAGTGA AAAAAACAGA TGAGTAAGTT 1800
AAGAGTTGGT CATCTGGAAA GAAGAAAACT CAGTAGGCAC CTTCTTTTGT TTTTTCTTGT 1860
GGTGTCCGGA TCAGCATCCT GCATGTGAGA TTCATCCACG TTGTCCTGTC TAGCAGTAGT 1920
TCAGTTCTCT TCATββTTAT GTCTGGTTTC ATTCTATGAT TATATCACAA TTTATCTATT 1980
CTACACTTGG GTGGCAGCTG CTTCAGATTT TTTACTTTTA AAAAATATAC TTAAAAGTGA 2040
ACTACAGGCA GGGCATGATG GCTCATβCCT GTAATGCCAG CACTTTGCCA AGGTGGGCAβ 2100
ATCACCTAAG GTCAGGAGTT CAAGATCAGC CTGGCCTAGA TGGCAAAACC CTGTCTCTAC 2160
TAAAAAATAC AAAAATTAGC TTGGTGTβGT GGTGGGCACA TGTAATCCCA GCTACTTGGG 2220
AGGCTGAGGT AGGGAGAACT GCTTAAACCT GAGAGβTGGA GGTTACAGTG AGTTGAGATT 2280
GTGCCACTGC ACTCTAGCCT GGGTGACAAA GCAAβACTCC ATCTCAGAAA AAAAAAATAA 2340
AAGTGAATTA CAACACT 2357
Seq ID NO: C65 DNA Sequence
Nucleic Acid Accession ff: NM_005266.3
Coding sequence: 122..1198
31
GGCACGAβGC CATTTTCAAA CAGTCCCTCC TGGGAGAACA CAGACAGGCA GAGGATTACA 60
ACACAAGGCA GCAAGCACTG GGAGACGAAA GTTTTGGCAT CTGTTCCCTG GCTGTGGCAA 120
GATGGGCGAT TGGAGCTTCC TGGGAAATTT CCTGGAGGAA GTACACAAGC ACTCGACC6T 180
GGTAGGCAAG GTCTGGCTCA CTGTCCTCTT CATATTCCGT ATGCTCGTGC TGGGCACAGC 240
TGCTCAGTCT TCCTGGGGGG ATGAGCAββC TGATTTCCGG TGTGATACGA TTCAGCCTGG 300
CTGCCAGAAT GTCTGCTACG ACCAGβCTTT CCCCATCTCC CACATTCGCT ACTGGGTGCT 360
GCAGATCATC TTCGTCTCCA CGCCCTCTCT ββTGTACATG GGCCACGGCA TGCACACTGT 420
GCGCATGCAG GAGAAGCeCA AGCTACGGGA GβCCGAGAGG GCCAAAGAGβ TCCGGGGCTC 480
TGGCTCTTAC GAGTACCCGβ TGGCAGAGAA GGCAGAACTG TCCTGCTGGG AGGAAGGGAA 540
TGGAAGGATT GCCCTCCAGG GCACTCTGCT CAACACCTAT GTβTβCAGCA TCCTGATCCG 600
CACCACCATG GAGGTGGGCT TCATTGTGGG CCAGTACTTC ATCTACGGAA TCTTCCTGAC 660
CACCCTGCAT GTCTGCCGCA GGAGTCCCTG TCCCCACCCG GTCAACTGTT ACGTATCCCG 720
GCCCACAGAG AAGAATGTCT TCATTGTCTT TATGCTGGCT GTGGCTGCAC TGTCCCTCCT 780
CCTTAGCCTG GCTGAACTCT ACCACCTGGG CTGGAAGAAG ATCAGACAGC GATTTGTCAA 840
ACCGCGGCAG CACATGGCTA AGTGCCAGCT TTCTGGCCCC TCTGTGGGCA TAGTCCAGAβ 900
CTGCACACCA CCCCCCGACT TTAATCAGTG CCTGGAGAAT GGCCCTGGGG GAAAATTCTT 960
CAATCCCTTC AGCAATAATA TββCCTCCCA ACAAAACACA GACAACCTGG TCACCGAGCA 1020
AGTACGAGGT CAβGAGCAGA CTCCTGGGGA AGGTTTCATC CAGGTTCGTT ATGGCCAGAA 1080
GCCTGAGGTG CCCAATGGAG TCTCACCAGG TCACCGCCTT CCCCATGGCT ATCATAGTGA 1140
CAAGCGACGT CTTACTAAGG CCAGCAGCAA GGCAAββTCA GATβACCTAT CAGTGTGACC 1200
CTCCTTTATG GGAGGATCAG GACCAGGTGβ GAACAAAGGA GGCTCAGAGA GGAAAGACGT 1260
GTCCCTTCTG AACTGATGCT TTCTCACTβT CATCACTGCT TGGCTCCTTT GAGCCCCGGG 1320
TCTCAATGAC βTTGCTCATT AATTCTACAA ACTATAACCA GGGCTCTGGG ATAGTAAGAG 1380
AGGTGACAAC CCACCCAGAC TGCAGTTCCC TCCCCACCCT CTACCCAGTA TACGAAGCCT 1440
TTCAGATTAC TCATGAAACA GGGTAGAGGG AAAGAAGGGA AGCATGGCAA AAGCTGGCCT 1500
GGAAGGβATA GCCAGAGββA TAGAATGACT CTCTCTCTAC ATACCAGCAG CATACCAAAT 1560
GCGTTCTCTA AGTTCCTACC TCCTTGACCT GATCACCCTC CCTCCTCCAA GGAAGAGCTC 1620 AAAGTTCCCA βCCAATAGAC AGCATGAATC AAGGAACTTG CATTATATGT GCTCTTGAAT 1680
CTGTTGTCTC CATGGACCAT TCCTCGGAGT AGTGGTGAGA TGGCCTTGGG TTGCCCTTGβ 1740
CTTCTCCTCC CTCTACTCAG CCTTAAAAAG GGCTTCTTGG AACTTTACCA GCAGCCTCAG 1800
CTTTACAAAT GCCTTGGTAT GTACCTCTGG CAAATGCCCT GGTATGTACC TCTGGCAAAT 1860
GCCCCACCTT GGTGATGTTG CAACCTTTCC TTCTβCTACβ GTGTACACCT AGCCTGTGCA 1920
GGTGTCAGCC CTGCTAGGGA GTCACTGTAC ACACAAACTC TACTββAATT CCTGCCAACA 1980
TCTGTCACCC TGCAGCTCCT TTACAGTTCA ATCCAATGAT AGAAACCATC CCTTCCCTTT 2040
CTcccTTβec TGTTCACCCA GCCATTCCCT GAAGGCCTTA CCAACAGGAA TATCCAAGAA 2100
GCTGTTGTCC TCTCTCGAAC CCTGACCAGA TCATCAGCCA CTGAGβCCAG TGGAATTTCC 2160
CCAGGCCTTG TTAAAAAAAA AAAAAAAAAA 2190
Seq ID NO: C66 DNA Sequence
Nucleic Acid Accession ff: NM_014459.2
Coding sequence: 738..3407
11 21 31 41 51
I I I I I I
GTAGATGCAG TCCGCCGCCG GCGCTGCCTC AGCCAGCAAT GCAAGATTAG ATCTCTAAAT 60
GCAGCAAAAC ACTGCCTGAA AACAGACCββ CCCGCGCAGC AAGCAGACAT TTCACGGTGC 120
GCTGGββAAG CTTCAAAATA TATCTGTGAC TCTGTCTTCG TTGCTCTTCA TCCCCATCAA 180
TTTCATCACG GGAGβCGAGC AGCAAGTAAG AATTTCACTT TCGGATCTGC CTAGAGACAC 240
ACCTCCCTGG TCCCTCCCCC ACTCGATGTG AAGAβTATTC CGGAGTCTCC GGβCGGGAGT 300
AGATTTGCAG CACCCTAGCG GGAβCGAGGA AAACCTACTG ATTCTTTAGC TCATTATCAT 360
CTCTCCCAGA CGAGATTTCC TTCTTATCGC CTGCCTCATC GCTCAAβTTT GAGCCTCCCG 420
AAGTCCGGGC GGGAGAGACG AAACCCCTGG CTCACCCCCA GCCGCAGGAA GCCACCGCCT 480
TGCTCCAAβC CCCTGCAGCT CTGCTGCACC GCAGCTTCTC ACCCAGTGCG GATGCTGTAG 540
ATCAACAGβT TCAβββAACT TGAGCAGAAT AAGGAGAGAC CACCGGGTGC CGCAGCTCGG 600
GTGCAGAGGG AAAAAAGGAC CCATAGACTT βTGGCTCGCG TCGCGCβCβC ACGCTGCGCC 660
AGGGCCCCAG GCTGGCGCGC ACTCCCTCTC TGGCTCCTCC AGTCCGATTG CTCCTGCCCC 720
CACCTTACAG GTCTGGGATG TACCTTTCCA TCTGTTGCTβ CTTTCTTCTA TGGGCCCCTG 780
CCCTCACTCT CAAGAACCTC AACTACTCCG TGCCGGAGGA GCAACGGGCC GGCACGGTGA 840
TCGGGAAGAT CGGCAGGGAT GCTCGACTGC AGCCTGGGCT TCCGCCTGCA GAGCGCGGCG 900
GCGGAGGGCG CAGCAAGTCG GGTAβCTACC GGGTGCTGGA GAACTCCGCA CCGCACCTGC 960
TGGACGTGGA CGCAGACAGC GGGCTCCTCT ACACCAAGCA GCGCATCGAC CGCGAGTCCC 1020
TGTGCCGCCA CAATGCCAAG TGCCAGCTGT CCCTCGAGGT GTTCGCCAAC GACAAGGAGA 1080
TCTGCATGAT CAAGGTAGAG ATCCAGGACA TCAACGACAA CGCCCGCTCC TTCTCCTCGG 1140
ACCAGATCGA AATGGACATC TCGGAGAACG CTGCTCCGββ CACCCGCTTC CCCCTCACCA 1200
GCGCACATGA CCCCGACGCC GGCGAGAATG GGCTCCGCAC CTACCTGCTC ACGCGCGACG 1260
ATCACGGCCT CTTTGGACTG GACGTTAAGT CCCGCGGCβA CGGCACCAAG TTCCCAGAAC 1320
TGGTCATCCA GAAGGCTCTG GACCGCGAGC AACAGAATCA CCATACGCTC GTGCTGACTG 1380
CCCTGGACGG TGGCGAGCCT CCACGTTCCG CCACCGTACA GATCAACGTG AAGGTGATTG 1440
ACTCCAACGA CAACAGCCCG GTCTTCGAGG CGCCATCCTA CTTGβTGGAA CTGCCCGAGA 1500
ACGCTCCGCT GGGTACAGTG GTCATCGATC TGAACGCCAC CGACGCCGAT GAAGGTCCCA 1560
ATGGTGAAGT GCTCTACTCT TTCAGCAGCT ACGTGCCTGA CCGCβTβCGG GAGCTCTTCT 1620
CCATCGACCC CAAGACCGGC CTAATCCGTβ TβAAGGGCAA TCTGGACTAT GAGGAAAACG 1680 βGATGCTGGA GATTGACGTG CAGGCCCGAG ACCTGGGGCC TAACCCTATC CCAGCCCACT 1740 eCAAAGTCAC GGTCAAGCTC ATCβACCGCA ACGACAATGC GCCGTCCATC GβTTTCGTCT 1800
CCGTGCGCCA GGGGGCGCTG AGCβAGGCCG CCCCTCCCGG CACCGTCATC GCCCTGGTGC 1860
GGGTCACTCA CCGGGACTCT GGCAAGAACG GACAGCTGCA GTGTC6GGTC CTAGGCGGAG 1920
GAβββACGGG CGGCGGCGGG GGCCTGGGCG GGCCCGGGGG TTCCGTCCCC TTCAAGCTTG 1980
AGGAGAACTA CGACAACTTC TACACGGTGG TGACTGACCG CCCGCTGGAC CGCGAGACAC 2040
AAGACGAGTA CAACβTGACC ATCGTGGCGC GGGACGGβββ CTCTCCTCCC CTCAACTCCA 2100
CCAAGTCGTT CGCGATCAAβ ATTCTAGACG AGAACβACAA CCCβCCTCGG TTCACCAAAG 2160
GGCTCTACGT GCTTCAGβTG CACβAβAACA ACATCCCGGG AGAGTACCTG GβCTCTβTGC 2220
TCGCCCAGGA TCCCGACCTG GGCCAGAACG GCACCGTATC CTACTCTATC CTGCCCTCGC 2280
ACATCGGCGA CGTGTCTATC TACACCTATG TGTCTGTGAA TCCCACGAAC GGGGCCATCT 2340
ACGCCCTGCG CTCCTTTAAC TTCGAβCAβA CCAAGGCTTT TβAGTTCAAG GTβCTTβCTA 2400
AGGACTCGGG GGCGCCCGCG CACTTGGAGA GCAACGCCAC GGTGAGGGTβ ACAβTβCTAβ 2460
AC6T6AATGA CAACGCGCCA GTGATCGTGC TCCCCACGCT GCAGAACGAC ACCGCGGAGC 2520
TGCAGβTGCC GCGCAACGCT GGCCTGGGCT ATCTGGTGAG CACTGTGCGC GCCCTAGACA 2580
GCGACTTCGG CGAGAGCGGG CGTCTCACCT ACGAβATCβT GGACGGCAAC GACGACCACC 2640
TGTTTGAGAT CGACCCGTCC AGCGGC6AGA TCCGCACGCT GCACCCTTTC TGGGAβGACβ 2700
TGACGCCCGT GGTGGAGCTG βTββTβAAGG TGACCGACCA CGGCAAGCCT ACCCTGTCCG 2760
CAGTβGCCAA GCTCATCATC CGCTCGGTGA GCGGATCCCT TCCCGAGGββ βTACCACGGG 2820
TGAATGGCGA βCAGCACCAC TGGGACATGT CGCTGCCGCT CATCGTGACT CTGAGCACTA 2880
TCTCCATCAT CCTCCTAGCG GCCATGATCA CCATCGCCGT CAAGTβCAAG CGCGAGAACA 2940
AGGAGATCCG CACTTACAAC TGCCGCATCG CCGAGTACAG CCACCCGCAG CTGGGTGGGG 3000
GCAAGGGCAA GAAGAAGAAG ATCAACAAAA ATGATATCAT GCTGGTβCAβ AGCGAAGTGG 3060
AGGAGAGGAA CGCCATGAAC GTCATGAACG TGGTGAGCAG CCCCTCCCTG GCCACCTCCC 3120
CCATGTACTT CGACTACCAβ ACCCCCCTGC CCCTCAGCTC GCCCCGGTCG GAGGTGATGT 3180
ATCTCAAACC GGCCTCCAAC AACCTGACTG TCCCTCAGβG GCACGCGGGC TGCCACACCA 3240
GCTTCACCGG ACAAGGGACT AATβCAAGCG AGACCCCTGC CACTCGGATG TCCATAATTC 3300
AGACAGACAA TTTTCCCGCA GAGCCCAATT ACATGGGCAG CAGGCAGCAG TTTGTTCAAA 3360
GTATTTCAGT AGCTCCACGT TTAAβGACCC AGAAAβAGCC AGCCTGAGAβ ACAβTβββCA 3420 CGβGGACAGT GATCAGGCTβ ACACTβACCA AGACACTAAC AAAGGCTCCT GCTGTGACAT 3480 CTCTGTTAGG GAGβCACTCA AGATGAAAAC TACTTCAACT AAAAβCCAAC GACTTGAACA 3540 AGAAGCAGAA GAGTGTGTTA ATTGCACAGA TGAATGCCGA GTGCTTGGTC ATTCTGACAG 3600 GTGCTGGATG CCACAGTTCC CTGCAGCCAA TCAGGCTGAA AATGCAGATT ACCGCACAAA 3660 TCTCTTTGTA CCTACAGTTG AAβCTAATCT TGAGACTGAG ACTTACGAAA CTGTGAATCC 3720 CACTGGGAAA AAGACTTTTT GTACATTTGG AAAAGACAAG CGAGAGCACA CTATTCTCAT 3780 TGCCAACGTT AAACCTTATT TAAAAGCCAA ACGTGCCCTβ AGCCCTCTCC TCCAAGAGGT 3840 CCCCTCAGCA TCAAGCAGCC CAACCAAGGC GTGCATCGAG CCTTGCACCT CAACAAAAGβ 3900 CTCCCTGGAT GGCTGTGAAG CAAAACCAGG AGCCCTCβCT GAAGCAAGCA GTCAGTACTT 3960 GCCCACTGAC AGTCAATATC TGTCACCTAG TAAGCAACCA AGAGACCCTC CCTTCATGGC 4020 TTCCGATCAG ATGGCAAGGG TCTTTGCAGA TGTGCATTCC AGAGCCAGCC GβGATTCCAG 4080
TGAGATGGGT GCTGTTCTTG AGCAGCTTGA CCACCCCAAC AGGGATCTGG GCAGAGAGTC 4140
TGTGGATGCA GAGGAAGTTG TGAGAGAAAT TGATAAGCTT TTGCAAGACT GCCGGGGAAA 4200
CGACCCTGTG GCTGTGAGAA AGTGAAAAAA GAAAAAAAAA AAGGCATTGG CATTTTCTTG 4260
TCTCTTCTGT TGATTTAAAA ATGATCCCTC CTGGTGATAA CCCATTTTAC AGGGATGAAG 4320
AAAGACCAAT GCTGCTTTAA GGCTTTTAGT GAACATCTGA AGTGCCCACA AGTATGTTCT 4380
TTCCACTGCT GATTTCTTTT TCAGAGATAA CAATGGTTTC GTTTTGACCA AACTTGTATT 4440
AGGACAGAAT TAATGATGCT TAAAGAβAAA AGAAAAAAAG AGAGAAGAAA AAGGAGAGAT 4500
GAAAAAGGAG GATGAGGAGA AGAATTACCT TTTGACAATC TGTTAGGAAG GTATGCAGTG 4560
TGAGAACTGA AGTATTTCTG ATCACTCTCA GACTGTCCTC CGTGATTTAT GCTGACTTAA 4620
CTGTTTACCT ATAAACCCCA TACAAAGCAG GGTCATAATT TGTGATCTβT GGTGGATTTC 4680
TAGCAGTCAT CACAGGCTTC TACTGAAAGT CCTGAAAAGA CCTTGCAGTA GTCCAAGCTA 4740
CACCAAACAT TAACACATAT TTGTGGTAAA CATTTCTGTA TAAAGTTACC TGACACACAT 4800
ATAAACACAA GGAACATTCC ATATCATTAG TCGAAAACAA AAACAAAAAA AAAACCTTTG 4860
GTCATTTGTA AGACATCTCA TGTCATATAA AAGTTAAATβ TAAAAAGATA CAGTCCATTT 4920
TGTCCTGCAC ACACGTAGAC TAATTCACGT CAAAAAAAAA AAAAAA 4966
Seq ID NO: C67 DNA Sequence Nucleic Acid Accession #: NM_005601.2 Coding sequence: 101..598
1 11 21 31 41 51
I I I I I I
CCCAGβAGTC TGGGTGCACA GCCTCCTTCT CTCTGAGATT CAAGAβTCTG ATCAGCAβCC 60
TCTTCCTCCT CCAGGACCCA GAAGCCCTGA GCTTATCCCC ATGβAβCTCT GCCGGTCCCT 120
GGCCCTGCTG GGGGGCTCCC TGGGCCTGAT GTTCTGCCTG ATTGCTTTGA GCACCGATTT 180
CTGGTTTGAG GCTGTGββTC CCACCCACTC AGCTCACTCG GGCCTCTGGC CAACAGGGCA 240
TGGGGACATC ATATCAGGCT ACATCCACGT GACGCAGACC TTCAGCATTA TGCCTGTTCT 300
GTGG6CCCTG GTGTCCGTGA GCTTCCTGGT CCTGTCCTGC TTCCCCTCAC TGTTCCCCCC 360
AGGCCACGGC CCGCTTGTCT CAACCACCGC AGCCTTTGCT GCAGCCATCT CCATGGTGGT 420
GGCCATGGCG GTGTACACCA GCGAGCGGTG G6ACCAGCCT CCACACCCCC AGATCCAGAC 480
CTTCTTCTCC TGGTCCTTCT ACCTGGGCTG GβTCTCAGCT ATCCTCTTGC TCTGTACAGG 540
TGCCCTGAGC CTG6GTGCTC ACTGTGGCGG TCCCCGTCCT GGCTATGAAA CCTTGTGAGC 600
AGAAGGCAAG AGCGGCAAGA TGAGTTTTGA GCGTTGTATT CCAAAGGCCT CATCTGβAGC 660
CTCGGβAAAG TCTGGTCCTA CATTTGCCCβ CCCTTCCA6C CCTTCCCCAG CCCCTCCTCT 720
TGTTTCTTCA TTCATTCAAC AAAATTTGGC TGGAAAAAAA AAAAAAAAAA AAAAAAAAAA 780
AAA 783
Seq ID NO: C68 DNA Sequence
Nucleic Acid Accession #: NM_006433.2
Coding sequence: 129..566 1 11 21 31 41 51 i i i i i i
GTATCTβTGG TAAACCCAGT βACACGGGGG AGATGACATA CAAAAAGGGC AGGACCTGAG 60
AAAGATTAAG CTGCAGGCTC CCTGCCCATA AAACAGGGTG TGAAAGGCAT CTCAGCGGCT 120
GCCCCACCAT GGCTACCTGG GCCCTCCTGC TCCTTGCAGC CATGCTCCTG GGCAACCCAG 180
GTCTGGTCTT CTCTCGTCTG AGCCCTGAGT ACTACGACCT GGCAAGAGCC CACCTGCβTG 240
ATGAGGAGAA ATCCTGCCCG TGCCTGGCCC AGGAGGGCCC CCAGGGTGAC CTGTTGACCA 300
AAACACAGGA GCTGGGCCGT GACTACAGGA CCTGTCTGAC GATAGTCCAA AAACTGAAGA 360
AGATGβTGGA TAAGCCCACC CAGAGAAGTG TTTCCAATGC TGCβACCCGG GTGTGTAGGA 420
CGGGGAGGTC ACGATGβCGC GACGTCTGCA GAAATTTCAT GAGGAβGTAT CAGTCTAGAG 480
TTACCCAGGG CCTCGTGGCC GGAGAAACTG CCCAGCAGAT CTGTGAGGAC CTCAGGTTGT 540
GTATACCTTC TACAGGTCCC CTCTGAGCCC TCTCACCTTG TCCTGTGGAA GAAGCACAGG 600
CTCCTGTCCT CAGATCCCGG GAACCTCAGC AACCTCTGCC GGCTCCTCGC TTCCTCGATC 660
CAGAATCCAC TCTCCAGTCT CCCTCCCCTG ACTCCCTCTG CTGTCCTCCC CTCTCACGAG 720
AATAAAGTβT CAAβCAAG 738
Seq ID NO: C69 DNA Sequence
Nucleic Acid Accession #: NM_002985.2
Coding sequence: 69..344
1 11 21 31 41 51
I I I I I I
GCTGCAGAGG ATTCCTGCAG AGGATCAAGA CAGCACGTGβ ACCTCGCACA GCCTCTCCCA 60
CAGGTACCAT GAAGGTCTCC βCββCAGCCC TCGCTGTCAT CCTCATTGCT ACTGCCCTCT 120
GCGCTCCTGC ATCTGCCTCC CCATATTCCT CGGACACCAC ACCCTGCTGC TTTGCCTACA 180
TTGCCCGCCC ACTGCCCCGT GCCCACATCA AββAβTATTT CTACACCAGT GGCAAGTGCT 240
CCAACCCAGC AGTCGTCTTT GTCACCCGAA AGAACCCCCA AGTGTGTGCC AACCCAGAGA 300
AGAAATGGGT TCGGGAGTAC ATCAACTCTT TGβAGATGAG CTAGGATGGA GAGTCCTT6A 360
AGCTGAACTT ACACAAATTT GCCTGTTTCT GCTTGCTCTT GTCCTAGCTT GGGAGGCTTC 420
CCCTCACTAT CCTACCCCAC CCGCTCCTTG AAGGGCCCAG ATTCTACCAC ACAGCAGCAG 480
TTACAAAAAC CTTCCCCAGG CTGGACGTGG TGGCTCACGC CTGTAATCCC AGCACTTTGG 540
GAGGCCAAGG TGGGTGGATC ACTTGAGGTC AGGAGTTCGA βACCAGCCTG GCCAACATGA 600
TGAAACCCCA TCTCTACTAA AAATACAAAA AATTAGCCGG GCGTGGTAGC GGGCGCCTGT 660
AGTCCCAGCT ACTCGGGAGG CTGAGGCAGG AGAATGGCGT GAACCCGβGA GGCGGAGCTT 720
GCAGTGAGCC GAGATCGCGC CACTGCACTC CAGCCTGGGC GACAGAGCGA GACTCCGTCT 780
CAAAAAAAAA AAAAAAAAAA AAAATACAAA AATTAGCCGG GCGTGGTGGC CCACGCCTGT 840
AATCCCAGCT ACTCGGGAGG CTAAGGCAGG AAAATTGTTT GAACCCAGGA GGTGGAGGCT 900
GCAGTGAGCT GAGATTGTGC CACTTCACTC CAGCCTGGGT GACAAAGTGA GACTCCGTCA 960
CAACAACAAC AACAAAAAGC TTCCCCAACT AAAGCCTAGA AGAGCTTCTG AGGCGCTGCT 1020
TTGTCAAAAG GAAGTCTGTA GGTTCTGAGC TCTGGCTTTG CCTTGGCTTT GCCAGGGCTC 1080 TGTGACCAGG AAGGAAGTCA GCATGCCTCT AβAGGCAAGG AGGGGAGGAA CACTGCACTC 1140 TTAAGCTTCC GCCGTCTCAA CCCCTCACAG GAβCTTACTβ GCAAACATGA AAAATCGβCT 1200 TACCATTAAA βTTCTCAATG CAACCATAAA AAAAAAA 1237
Seq ID NO : C70 DNA Sequence
Nucleic Acid Accession ft : NM_022154 .2
Coding sequence : 1381. .1722
1 11 21 31 41 l l l l l
AGTGTGGTTT TAGTTTTTCC TAAGAAGTGG CGTGGTTTGG GGCTTTATAT CCGGGAGGAG 60 CATATGTACG CAAATCCTGG GGCGTTTGCA AACCCGGATC CGGGGCGTCT GGCCCCATGC 120 CCGGCCGβGC GTTTGAGGGC TACTGCCACG CAGCGTTTCT GGAGCCTGGG eβCTGGTβcc 180 CTGGTGGCCT TTATCTCTGT CCCCCTTTGT CCTCTTTATC TCAGGCTCTC CAGGAGGCCG 240 βGGGGCCCAC TCCGCCTATC GCTCCCCTCG GCTACGCTGC CACTCCAATG CCCCGCAββT 300 CGCGAGCTGC TGTTCTTTCG AAGβCGCCGG AβAACCAβGβ CCGTCCCGCβ CCACCTCTβA 360 CTCGGAGCAG CGCCGAGCAC TGACGCTCCC βCCCTTβGGC AAGGACGCCA GTGCGCCCβC 420 GCGCGTCCCT CTGCGCGGCA GCCCGTCGCG GβCCCTCAAG GGGAAGCCCA GGCCAGβATG 480 GCCCCGGGTC GCGCGGTGGC CGGGCTCCTG TTGCTGGCGG CCGCCββCCT CβGAGGAGTG 540 GCGGAGβGGC CAGGGCTAGC CTTCAGCGAβ GATGTGCTGA GCGTβTTCGG CGCβAATCTG 600 AGCCTGTCGG CGGCGCAGCT CCAGCACTTβ CTGβAGCAGA TGGGA6CCGC CTCCCGCGTβ 660 GGCGTCCCGG AβCCTβGCCA GCTGCACTTC AACCAGTGTT TAACTGCTGA AGAGATCTTT 720 TCCCTTCATG GCTTTTCAAA TGCTACCCAA ATAACCAGCT CCAAATTCTC TGTCATCTGT 780 CCAGCAβTCT TACAGCAATT GAACTTTCAC CCATGTGAGG ATCGGCCCAA GCACAAAACA 840 AGACCAAβTC ATTCAGAAGT TTβββGATAT GGATTCCTGT CAGTGACGAT TATTAATCTG 900 GCATCTCTCC TCGGATTGAT TTTGACTCCA CTGATAAAGA AATCTTATTT CCCAAAGATT 960 TTGACCTTTT TTGTGGGGCT GGCTATTGGG ACTCTTTTTT CAAATGCAAT TTTCCAACTT 1020 ATTCCAGAGG CATTTGGATT TGATCCCAAA GTCGACAGTT ATGTTGAGAA GGCAGTTGCT 1080 GTGTTTGGTG GATTTTACCT ACTTTTCTTT TTTGAAAGAA TGCTAAAGAT GTTATTAAAG 1140 ACATATGGTC AGAATGGTCA TACCCACTTT GGAAATGATA ACTTTGGTCC TCAAGAAAAA 1200 ACTCATCAAC CTAAAGCATT ACCTGCCATC AATGGTGTGA CATGCTATGC AAATCCTGCT 1260 GTCACAGAAG CTAATGGACA TATCCATTTT GATAATGTCA GTGTGGTATC TCTACAGGAT 1320 GβAAAAAAAG AGCCAAGTTC ATGTACCTGT TTGAAGGGGC CCAAACTGTC AGAAATAGGG 1380 ACGATTGCCT GGATGATAAC CCTCTGCGAT GCCCTCCACA ATTTCATCGA TGGCCTGGCG 1440 ATTGGGGCTT CCTGCACCTT GTCTCTCCTT CAGGGACTCA GTACTTCCAT AGCAATCCTA 1500 TGTGAGGAGT TTCCCCACGA GTTAGGAGAC TTTGTGATCC TACTCAATGC AGGGATGAGC 1560 ACTCGACAAG CCTTGCTATT CAACTTCCTT TCTGCATGTT CCTGCTATGT TGGGCTAGCT 1620 TTTGGCATTT TGGTGGGCAA CAATTTCGCT CCAAATATTA TATTTGCACT TGCTGGAGGC 1680 ATGTTCCTCT ATATTTCTCT GGCAGATATG TTTCCAGAGA TGAATGATAT GCTGAGAGAA 1740 AAGGTAACTG GAAGAAAAAC CGATTTCACC TTCTTCATGA TTCAGAATGC TGGAATGTTA 1800 ACTGGATTCA CAGCCATTCT ACTCATTACC TTGTATGCAG GAGAAATCGA ATTGGAGTAA 1860 TAGAAAATGG AAGATGGTβT TGTTAATAAA GGCATTTAAT AGATAAAAAC ATCTCCAAAA 1920 AGGATTTTGA AGCTGATCCT ATTTAGTTAA AAAGATAATT TTGCTTTCAA CTGTAGGTCC 1980 AGAAAACTAA TTATTGGCAT CAGTCTGTGA AATAGTCCAT TATTTβTTβT TAAAAATGCT 2040 TCAAAAGGTT TTCAGTGTCA GTCTGAGATG CCTGGTATAT AGGAGCCTTT GGGAAATACT 2100 TATTTTTCAG TATTCCATGC ATATTAGATA TCACCATGAA GCAAGAGACA TGCATTCTAT 2160 AATCATGTAG ACACTCAGAC TCAGGGGAAA ATACAAGTTA TATCCTGAAA GCCTTTAAAA 2220 CTCTATGGTA GGATCAAAGA TTCAAATGGT TTCAGAGAGG TTTTATTTCA ATTAATTTGT 2280 TCTAGTGCTT TCAAGAGCAA βTACATCAAA ATGTAGAAGG TAAAATGTAT GCAACACTAA 2340 TATAAATTAT TCCAAGTCTT TAAGGAGCCA AAGAAAAAAA AGATTTCTCA CAGCTTTTTG 2400 TTCTGTTTTG TATTTCAATT AGGAACTTGC AGTATTATTT TGAAAACCAT TCTAAAATAA 2460 TAGGAGTTAG GAAATAAATA AAGTTTTGCT AβCCCTGCTA AGTTCAGGCT TAGAββCTTA 2520 TCGCTAAGTN TAAACTTCAC CAGATTCCAC GAAAAGCTGG ATAGCTTTTT TTCTGACTTA 2580 TGTTGTGβTT GCACCCCTCA CAAATGGCAG AACAGTATGT AAAGCTGGTA ACACCTCGGT 2640 TTCAGTGCAC CATGTGTTTG CTTTGTGAAG GTGAAGAATA TGTTGGTTTA GAGAAAGAAA 2700 TTGGATGTAA TTTTATGCAA TTTACTTTTA AAGACAAACA TAACTATTTA GCAGAGAATA 2760 TTTTAATAAA TGCAAAACAA CAGCTGGACT GCTGTACATC AAGGACAGAT TAACTGGAAA 2820 ACATATGTTC CTTATGTGTG ATTβAGAGCC ATTCAGAAAA GACTTCCTTT GTGTTCAGCC 2880 TATACTTTTC CATATGGTAT ACCTTGAAAA AAATTAGCAC ACCATG6TTA TTTTTCTACC 2940 TTTTATAAAA GACAGAGCCT GTTTACTCAT TTAGAAGATA GAGAAAATTG GTCTAAAATT 3000 GAACATCCTA GATTCACACT CCCAAGTCAC TTAAGGTGAT TTGATGGTβA . GGAAAATβAT 3060 TGACAAAGCC CAACAATGAT CTCAGGAATT ACATTTTCCA ACAGACCAAA . AAATGTTTTC 3120 ATGTAGCAGC AATGCAGATT TGβTβAATAT TTAATATATA TTTTAGTATG TATTTCACTT 3180 TATGACTGAC AATTAAAAAA TATTGTTTGβ CCAAATAGTA AACACCCTTT TGAAACCATG 3240 AAAAAA 3246
Seq ID NO : C71 DNA Sequence
Nucleic Acid Accession ft : NM.004184.2
Coding sequence : 188 . .1603
11 21 31 41 51
I I
CGAAAAAAGA G 1GGGAAGAGT I
ATTAAAGACC ATTTCTGGCT GGGCAG6GCA CTCTCAGCAG 60 CTCAACTGCC CAGCGTGACC AGTGGCCACC TCTGCAGTβT CTTCCACAAC GTGGTGTTGA 120 CTCGTCTGCT GAACAAATCC TCTGACCTCA GGCCGGCTGT GAACGTAGTT CCTGAGAGAT 180 AGCAAACATC CCCAACAGTG AGCCCGCATC TCTGCTGGAG CTGTTCAACA GCATCGCCAC 240 ACAAGGGGAG CTCGTAAGGT GCCTCAAAGC GGGAAATGCG TCAAAGGATG AAATTGATTC 300 TGCAGTAAAβ ATGTTGGTGT CATTAAAAAT GAGCTACAAA GCTGCCGCGG GGGAGGATTA 360 CAAGGCTGAC TGTCCTCCAG GGAACCCAGC ACCTACCAGT AATCATGGCC CAGATGCCAC 420 AGAAGCTGAA GAGGATTTTG TGGACCCATG GACAGTACAG ACAAGCAGTβ CAAAAGGCAT 480 AGACTACGAT AAGCTCATTG TTCGGTTTGG AAGTAGTAAA ATTGACAAAG AGCTAATAAA 540 CCGAATAGAG AGAGCCACCG GCCAAAGACC ACACCACTTC CTGCGCAGAG GCATCTTCTT 600 CTCACACAGA GATATGAATC AGGTTCTTGA TGCCTATGAA AATAAGAAGC CATTTTATCT 660
GTACACGGGC CGGGGCCCCT CTTCTGAAGC AATGCATGTA GGTCACCTCA TTCCATTTAT 720
TTTCACAAAG TGGCTCCAGG ATGTATTTAA CGTGCCCTTG GTCATCCAGA TGACGGATGA 780
CGAGAAGTAT CTGTGβAAGG ACCTGACCCT GGACCAGCCC TATGGCGATG CTGTTGAGAA 840
TGCCAAGGAC ATCATCGCCT GTβGCTTTGA CATCAACAAG ACTTTCATAT TCTCTGACCT 900
GGACTACATG GGGATGAGCT CAGGTTTCTA CAAAAATGTG GTGAAGATTC AAAAGCATGT 960
TACCTTCAAC CAAGTGAAAG GCATTTTCGG CTTCACTGAC AGCGACTGCA TTGGGAAGAT 1020
CAGTTTTCCT GCCATCCAGG CTGCTCCCTC CTTCAGCAAC TCATTCCCAC AGATCTTCCG 1080
AGACAGGACG GATATCCAGT GCCTTATCCC ATGTGCCATT GACCAGGATC CTTACTTTAG 1140
AATGACAAGG GACGTCGCCC CCAGGATCGG CTATCCTAAA CCAGCCCTGT TGCACTCCAC 1200
CTTCTTCCCA GCCCTGCAGG GCGCCCAGAC CAAAATGAGT GCCAGCGACC CAAACTCCTC 1260
CATCTTCCTC ACCGACACGG CCAAGCAGAT CAAAACCAAG GTCAATAAGC ATGCGTTTTC 1320
TGGAGGGAGA GACACCATCG AGGAGCACAG GCAGTTTGGG GGCAACTGTG ATGTGGACGT 1380
GTCTTTCATG TACCTGACCT TCTTCCTCGA GGACGACGAC AAGCTCGAGC AGATCAGGAA 1440
GGATTACACC AGCGGAGCCA TGCTCACCGG TGAβCTCAAG AAGGCACTCA TAGAGGTTCT 1500
GCAGCCCTTG ATCGCAGAGC ACCAGGCCCG GCβCAAGGAG GTCACGGATG AGATAGTGAA 1560
AGAGTTCATG ACTCCCCGGA AGCTGTCCTT CGACTTTCAG TAGCACTCGT TTTACATATG 1620
CTTATAAAAG AAGTGATGTA TCAGTAATGT ATCAATAATC CCAGCCCAGT CAAAGCACCG 1680
CCACCTGTAG GCTTCTGTCT CATGGTAATT ACTGGGCCTG GCCTCTGTAA GCCTGTGTAT 1740
GTTATCAATA CTGTTTCTTC CTGTGAGTTC CATTATTTCT ATCTCTTATG GGCAAAGCAT 1800
TGTGGGTAAT TGGTGCTGGC TAACATTGCA T6GTCGGATA GAGAA6TCCA GCTGTGAGTC 1860
TCTCCCCAAA GCACCCCCAC AGTGGAGCCT TCGβCTGGAA GTCCATGGGC CACCCTGTTC 1920
TTGTCCATGG AGGACTTCCG AGβGTTCCAA GTATACTCTT AAGACCCACT CTGTTTAAAA 1980
ATATATATTC TATGTATGCG TATATGβAAT TGAAATGTCA TTATTGTAAC CTAGAAAGTG 2040
CTTTGAAATA TTGATGTGGG GAGβTTTATT GAGCACAAGA TGTATTTCAG CCCATGCCCC 2100
CTCCCAAAAA GAAATTGATA AGTAAAAGCT TCGTTATACA TTTGACTAAG AAATCACCCA 2160
GCTTTAAAGC TGCTTTTAAC AATGAAGATT GAACAGAGTT CAGCAATTTT GATTAAATTA 2220
AGACTTGGGG GTGAAACTTT CCAGTTTACT GAACTCCAGA CCATGCATGT AGTCCACTCC 2280
AGAAATCATG CTCβCTTCcc TTGGCACACC AGTGTTCTCC TGCCAAATGA CCCTAGACCC 2340
TCTGTCCTGC AGAGTCAβGG TG6CTTTTCC CCTGACTGTG TCCGATGCCA AGGAβTCCTG 2400
GCCTCCGCAG ATGCTTCATT TTβACCCTTG GCTGCAGTGG AAGTCAGCAC AGAβCAβTGC 2460
CCTGGCTGTG TCCTGGACGG GTGGACTTAG CTAGGGAGAA AGTCGAGGCA GCAGCCCTCG 2520
AGGCCCTCAC AGATGTCTAG GCAβGCCTCA TTTCATCACG CAGCATGTGC AGGCCTGGAA 2580
GAGCAAAGCC AAATCTCAGG GAAGTCCTTG GTTGATGTAT CTGGGTCTCC TCTGGAGCAC 2640
TCTGCCCTCC TGTCACCCAG TAGAGTAAAT AAACTTCCTT GGCTCCTAAA AAA 2693
Seq ID NO: C72 DNA Sequence
Nucleic Acid Accession #: NM_004938.1
Coding sequence: 337..4632
1 11 21 31 41 51 1 1 i1 1 1 | 1 | 1
CGGAβGACAG CCGGACCGAG CCAACGCCGG GGACTTTGTT CCCTCCACGG AGGGGACTCG 60
GCAACTCGCA GCGGCAGGGT CTGβGGCCGG CGCCTGGGAG GGATCTGCGC CCCCCACTCA 120
CTCCCTAGCT GTGTTCCCGC CGCCGCCCCG GCTAGTCTCC GGCGCTββCG CCTATGGTCG 180 βCCTCCβACA GCGCTCCGGA GGGACCGGGG GAGCTCCCAG GCGCCCGGGA CTGGAGACTG 240
ATGCATGAGβ GGCCTACGGA GGCGCAGGAG CGβTGGTGAT GGTCTGGGAA GCGGAGCTGA 300
AGTCCCCTGG GCTTTβGTGA GGCβTβACAG TTTATCATGA CCGTGTTCAG GCAGGAAAAC 360
GTGGATGATT ACTACGACAC CGGCGAβGAA CTTGGCAGTG GACAGTTTGC GGTTGTGAAG 420
AAATGCCGTG AGAAAAGTAC CGGCCTCCAG TATGCCGCCA AATTCATCAA GAAAAGGAGG 480
ACTAAGTCCA GCCGGCGGGG TGTGAGCCGC GAGGACATCG AGCGGGAGGT CAGCATCCTG 540
AAGGAGATCC AGCACCCCAA TGTCATCACC CTGCACGAGG TCTATGAGAA CAAGACGGAC 600
GTCATCCTGA TCTTGGAACT CGTTGCAGGT GGCGAGCTGT TTGACTTCTT AGCTGAAAAG 660
GAATCTTTAA CTGAAGAGGA AGCAACTGAA TTTCTCAAAC AAATTCTTAA TGGTGTTTAC 720
TACCTGCACT CCCTTCAAAT CGCCCACTTT GATCTTAAGC CTGAGAACAT AATGCTTTTG 780
GATAGAAATG TCCCCAAACC TCGGATCAAG ATCATTGACT TTGGGTTGGC CCATAAAATT 840
GACTTTGβAA ATGAATTTAA AAACATATTT GββACTCCAG AGTTTGTCβC TCCTGAGATA 900
GTCAACTATG AACCTCTTGG TCTTGAGGCA GATATGTGGA GTATCGGGGT AATAACCTAT 960
ATCCTCCTAA GTGGGGCCTC CCCATTTCTT GGAGACACTA AGCAAGAAAC GTTAGCAAAT 1020
GTATCCGCTG TCAACTACGA ATTTGAGGAT GAATACTTCA GTAATACCAG TGCCCTAGCC 1080
AAAGATTTCA TAAGAAGACT TCTGβTCAAG GATCCAAAGA AGAGAATGAC AATTCAAGAT 1140
AGTTTGCAGC ATCCCTGGAT CAAGCCTAAA GATACACAAC AGGCACTTAG TAGAAAAGCA 1200
TCAGCAGTAA ACATGGAGAA ATTCAAGAAG TTTGCAGCCC GGAAAAAATG GAAACAATCC 1260
GTTCGCTTGA TATCACTGTG CCAAAGATTA TCCAGGTCAT TCCTGTCCAG AAGTAACATG 1320
AGTGTTGCCA GAAGCGATGA TACTCTGGAT GAGGAAGACT CCTTTGTGAT GAAAGCCATC 1380
ATCCATGCCA TCAACGATGA CAATGTCCCA GGCCTGCAGC ACCTTCTGGG CTCATTATCC 1440
AACTATGATG TTAACCAACC CAACAAβCAC GGβACACCTC CATTACTCAT TGCTGCTGGC 1500
TGTGGGAATA TTCAAATACT ACAGTTGCTC ATTAAAAGAG GCTCGAGAAT CGATGTCCAG 1560
GATAAβGGCG GGTCCAATGC CGTCTACTGG GCTGCTCGGC ATGGCCACβT CGATACCTTG 1620
AAATTTCTCA GTGAGAACAA ATGCCCTTTG GATβTGAAAG ACAAGTCTGG AGAGATβGCC 1680
CTCCACGTGG CAGCTCGCTA TββCCATGCT GACGTGGCTC AAGTTACTTG TGCAGCTTCG 1740
GCTCAAATCC CAATATCCAG GAGAAAGGAA GAAGAAACCC CCCTGCACTG TGCTGCTTGG 1800
CACGGCTATT ACTCTGTGGC CAAAGCCCTT TGTβAAβCCG GCTGTAACGT GAACATCAAG 1860
AACCGAGAAG GAGAGACGCC CCTCCTGACA GCCTCTGCCA GGGGCTACCA CGACATCGTG 1920
GAGTGTCTGG CCGAACATGG AGCCGACCTT AATGCTTGCG ACAAGGACGG ACACATTGCC 1980
CTTCATCTGβ CTGTAAGACG GTGTCAGATG GAGGTAATCA AGACTCTCCT CAGCCAAGGG 2040
TGTTTCGTCβ ATTATCAAGA CAGβCACGGC AATACTCCCC TCCATGTβGC ATGTAAAGAT 2100
GGCAACATGC CTATCGTGGT GGCCCTCTGT GAAGCAAACT GCAATTTGGA CATCTCCAAC 2160
AAGTATGGGC GAACGCCTCT GCACCTTβCG GCCAACAACG GAATCCTAGA CGTβGTCCGG 2220
TATCTCTGTC TGATGGGAGC CAGCGTTGAG GCGCTGACCA CGGACGGAAA GACGGCAGAA 2280
GATCTTGCTA GATCGGAACA GCACGAGCAC GTAGCAGGTC TCCTTGCAAG ACTTCGAAAG 2340
GATACβCACC GAGGACTCTT CATCCAGCAG CTCCGACCCA CACAGAACCT GCAGCCAAGA 2400
ATTAAGCTCA AGCTGTTTGG CCACTCGGGA TCCGGGAAAA CCACCCTTGT AGAATCTCTC 2460
AAGTGTGGGC TGCTGAGβAG CTTTTTCAGA AGGCGTCGGC CCAGACTGTC TTCCACCAAC 2520 TCCAGCAGGT TCCCACCTTC ACCCCTGGCT TCTAAGCCCA CAGTCTCAGT GAβCATCAAC 2580 AACCTGTACC CAGGCTGCGA GAACGTGAGT GTGAβGAGCC GCAGCATGAT GTTCGAGCCG 2640 GGTCTTACCA AAGGGATGCT GGAGGTGTTT GTββCCCCGA CCCACCACCC GCACTGCTCG 2700 GCCGATGACC AGTCCACCAA GGCCATCGAC ATCCAGAACG CTTATTTGAA TGGAGTTGGC 2760 GATTTCACCG TGTGGGAGTT CTCTGGAAAT CCTβTGTATT TCTGCTGTTA TGACTATTTT 2820 GCTGCAAATG ATCCCACGTC AATCCATGTT GTTGTCTTTA GTCTAGAAGA GCCCTATGAG 2880 ATCCAGCTGA ACCCAGTGAT TTTCTGGCTC AGTTTCCTGA AGTCCCTTGT CCCAGTTGAA 2940 GAACCCATAG CCTTCGGTGG CAAGCTGAAG AACCCACTCC AAGTTGTCCT GGTGGCCACC 3000 CACGCTGACA TCATGAATGT TCCTCGACCG GCTGGAGGCG AGTTTGGATA TGACAAAGAC 3060 ACATCGTTGC TGAAAGAGAT TAGGAACAGG TTTGGAAATG ATCTTCACAT TTCAAATAAG 3120 CTGTTTGTTC TGGATGCTGG GGCTTCTGGG TCAAAGGACA TGAAGGTACT TCGAAATCAT 3180 CTGCAAGAAA TACGAAGCCA GATT6TTTCG GTCTGTCCTC CCATGACTCA CCTGTGTGAG 3240 AAAATCATCT CCACGCTGCC TTCCTGGAGG AAGCTCAATG GACCCAACCA GCTGATGTCG 3300 CTGCAGCAGT TTGTGTACGA CGTβCAGGAC CAGCTGAACC CCCTGGCCAG CGAGGAGGAC 3360 CTCAGGCGCA TTGCTCAGCA GCTCCAGAGC ACAGGCGAGA TCAACATCAT βCAAAGTGAA 3420 ACAGTTCAGG ACGTGCTGCT CCTGGACCCC CGCTGGCTCT GCACAAACGT CCTGGGGAAG 3480 TTGCTGTCCG TGGAGACCCC ACGGGCβCTβ CACCACTACC GGGβCCGCTA CACCGTGGAG 3540 GACATCCAGC GCCTGβTGCC CGACAGCGAC GTGGAGGAGC TGCTGCA6AT CCTCGATGCC 3600 ATGGACATCT GCGCCCGGGA CCTGAGCAGC GββACCATGG TGGACGTCCC AGCCCTGATC 3660 AAGACAGACA ACCTGCACCG CTCCTGGGCT GATGAGGAGG ACGAGGTGAT GGTGTATGβT 3720 GGCGTGCGCA TCGTGCCCGT GGAACACCTC ACCCCCTTCC CATGTGGCAT CTTTCACAAβ 3780 GTCCAGGTGA ACCTGTGCCG GTGGATCCAC CAGCAAAGCA CAGAGGGCβA CGCGGACATC 3840 CGCCTGTGGG TGAATGGCTG CAAGCTGGCC AACCGTGGGG CCGAGCTGCT GGTGCTGCTG 3900 GTCAACCACG βCCAGGGCAT TGAGGTCCAG GTCCGTGGCC TGGAGACGGA GAAGATCAAG 3960 TGCTGCCTGC TGCTGGACTC GGTGTGCAGC ACCATTGAGA ACGTCATGGC CACCACGCTG 4020 CCAGGGCTCC TGACCGTGAA GCATTACCTG AGCCCCCAGC AGCTGCGGGA GCACCATGAG 4080 CCCGTCATGA TCTACCAGCC ACGGGACTTC TTCCGGGCAC AGACTCTGAA GGAAACCTCA 4140 CTGACCAACA CCATGGGGGG GTACAAGGAA AGCTTCAGCA GCATCATGTG CTTCGGGTGT 4200 CACGACGTCT ACTCACAGGC CAGCCTCGGC ATGβACATCC ATGCATCAGA CCTGAACCTC 4260 CTCACTCGGA GβAAACTGAG TCGCCTGCTG GACCCGCCCG ACCCCCTGGG GAAGGACTGG 4320 TGCCTTCTCG CCATGAACTT AGGCCTCCCT GACCTCGTGG CAAAGTACAA CACCAATAAC 4380 GGGGCTCCCA AGGATTTCCT CCCCAGCCCC CTCCACGCCC TGCTGCGGGA ATGGACCACC 4440 TACCCTGAGA GCACAGTGGG CACCCTCATG TCCAAACTGA GGGAGCTGGG TCGCCGGGAT 4500 GCCGCAGACC TTTTGCTGAA GGCATCCTCT GTGTTCAAAA TCAACCTGGA TGGCAATGGC 4560 CAGGAGGCCT ATGCCTCGAG CTGCAACAGC GGCACCTCTT ACAATTCCAT TAGCTCTGTT 4620 GTATCCCGGT GAβGGCAGCC TCTGGCTTGG ACAGGGTCTG TTTGGACTGC AGAACCAAGG 4680 GGGTβATGTA GCCCATCCTT CCCTTTGGAG ATGCTGAβGG TGTTTCTTCC TGCACCCACA 4740 GCCAGGGGGA TGCCACTCCT CCCTCCGGCT TGACCTGTTT CTCTGCCGCT ACCTCCCTCC 4800 CCGTCTCATT CCGTTGTCTG TGGATGGTCA TTGCAGTTTA AGAGCAGAAC AGATCTTTTA 4860 CTTTGGCCGC TTGAAAAGCT AGTβTACCTC CTCTCAGT6T TTTGGACTCC ATCTCTCATC 4920 CTCCAGTACC TTGCTTCTTA CTGATAATTT TGCTGβAATT CCTAACTTTT CAATGACATT 4980 TTTTTTAACT ATCATATTGA TTGTCCTTTA AAAAAβAAAA GTGCATATTT ATCCAAAATG 5040 TGTATTTCTT ATACGCTTTT CTGTGTTATA CCATTTCCTC AGCTTATCTC TTTTATATTT 5100 GTAGGAGAAA CTCCCATGTA TGGAATCCCA CTβTATGATT TATAAACAGA CAATATGTβA 5160 GTGCCTTTTG CAGAAGAGGG TGTGTTTGAA ATCATCGGAG TCAGCCAβGA βCTGTCACCA 5220 AGGAAACGCT ACCTCTCTGT CCCTTGCTGT ATGCTGATCA TCGCCAGAGG TGCTTCACCC 5280 TGAGTTTTGT TTTGTATTGT TTTCTGACAG TTTTTCTGTT TTGTTTGGCA AGGAAAGGGG 5340 AGAAGGGAAT CCTCCTCCAG GGTGATTTTA TGATCAGTGT TGTTGCTCTA GGAAGACATT 5400 TTTCCGTTTG CTTTTGTTCC AATGTCAATG TGAACβTCCA CATGAAACCT ACACACTGTC 5460 ATGCTTCATC ATTCCCTCTC ATCTCAGGTA GAAGGTTβAC ACAGTTGTAG GGTTACAGAβ 5520 ACCTATGTAA GAATTCAGAA GACCCCTGAC TCATCATTTβ TGGCAGTCCC TTATAATTββ 5580 TβCATAGCAG ATGGTTTCCA CATTTAGATC CTGGTTTCAT AACTTCCTGT ACTTGAAGTC 5640 TAAAAGCAGA AAATAAAGGA AGCAAGTTTT CTTCCATGAT TTTAAATTGT GATCGAGTTT 5700 TAAATTGATA GGAGGGAACA TGTCCTAATT , CTTCTGTCCT GAGAAGCATG TAATGTTAAT 5760 GTTATATCAT ATGTATATAT ATATATGCAC : TATGTATATA CATATATATT AATACTGGTA 5820 TTTTTACTTA ATCTATAAAA TGTCGTTAAA . AAGTTGTTTG TTTTTTTCTT TTTTTATAAA 5880 TAAACTGTTG CTCGTTAAAA AAAAAAAAAA 5910
Seq ID NO: C73 DNA Sequence
Nucleic Acid Accession #: NM_002081.1
Coding sequence: 222..1898
11 21 31
GGCTGCCCGA GCGAGCGTTC GGACCTCGCA CCCCGCGC6C CCCGCGCCGC CGCCβCCGCC 60
GGCTTTTGTT GTCTCCGCCT CCTCGGCCGC CβCCCCCTCT GβACCGCGAG CCGCGCGCGC 120
CGGGACCTTG GCTCTGCCCT TCGCβGGCGG GAACTGCGCA GβACCCGGCC AGGATCCGAG 180
AGAGGCGCGβ GCGGGTGGCC GββGGCGCCG CCGGCCCCGC CATGGAGCTC CGGGCCCGAG 240 eCTGGTGGCT GCTATGTGCG GCCGCAGCGC TGGTCGCCTG CGCCCGCGGG GACCCGGCCA 300
GCAAGAGCCG GAGCTGCGGC GAGGTCCGCC AGATCTACGG AGCCAAGβGC TTCAGCCTGA 360
GCGACGTGCC CCAGGGGGAG ATCTCGGGTG AGCACCTGCG GATCTGTCCC CAGGGCTACA 420
CCTGCTGCAC CAGCGAGATG GAGGAGAACC TGβCCAACCβ CAGCCATGCC GAβCTGGAGA 480
CCGCGCTCCG GGACAGCAGC CGCGTCCTGC AββCCATβCT TGCCACCCAG CTGCGCAGCT 540
TCGATGACCA CTTCCAGCAC CTGCTGAACG ACTCGGAGCβ GACGCTGCAG GCCACCTTCC 600
CCGGCGCCTT CGGAGAGCTβ TACACGCAGA ACGCGAGGGC CTTCCGGGAC CTGTACTCAG 660
AGCTGCGCCT βTACTACCGC GGTGCCAACC TGCACCTGGA GGAGACGCTG GCCβAGTTCT 720
GGGCCCGCCT GCTCGAGCGC CTCTTCAAGC AGCTGCACCC CCAGCTGCTG CTGCCTGATβ 780
ACTACCTGGA CTGCCTGGGC AAGCAGGCCG AGGCGCTGCG GCCCTTCGGG GAββCCCCβA 840
GAGAGCTGCG CCTGCGGGCC ACCCGTGCCT TCGTGGCTGC TCGCTCCTTT GTGCAGGGCC 900
TβGGCGTGβC CAGCGACGTG GTCCGGAAAG TGGCTCAGGT CCCCCTβGGC CCGGAGTGCT 960
CGAGAGCTGT CATGAAGCTG GTCTACTGTG CTCACTGCCT GGGAGTCCCC GGCGCCAβGC 1020
CCTGCCCTGA CTATTGCCGA AATGTGCTCA AGGGCTGCCT TGCCAACCAG GCCGACCTGG 1080
ACGCCGAGTG GAGGAACCTC CTGGACTCCA TGGTGCTCAT CACCGACAAG TTCTGGGGTA 1140
CATCGGGTGT GGAGAGTGTC ATCGGCAGCG TGCACACGTG GCTGGCGβAG GCCATCAACβ 1200 CCCTCCAGGA CAACAGGGAC ACGCTCACGG CCAACGTCAT CCAGGGCTGC GGGAACCCCA 1260
AGGTCAACCC CCAGGGCCCT GGGCCTβAGG AβAAGCGGCG CCGGGGCAAG CTGGCCCCGC 1320
GGGAGAGGCC ACCTTCAGGC ACGCTGGAGA AGCTGGTCTC TGAAGCCAAG GCCCAGCTCC 1380
GCGACGTCCA GGACTTCTGG ATCAGCCTCC CAGGGACACT GTGCAGTGAG AAGATGGCCC 1440
TGAGCACTGC CAGTGATGAC CGCTGCTGGA ACGGGATβGC CAGAGGCCGG TACCTCCCCG 1500
AGGTCATGGG TGACGGCCTG GCCAACCAGA TCAACAACCC CGAGGTGGAG GTβGACATCA 1560
CCAAGCCGGA CATGACCATC CGGCAGCAGA TCATGCAGCT GAAGATCATG ACCAACCGGC 1620
TGCGCAGCGC CTACAACGGC AACGACGTGG ACTTCCAGGA CGCCAGTGAC GACGGCAGCG 1680 βCTCGGGCAG CGGTGATGGC TGTCTGGATG ACCTCTGCGG CCGGAAGGTC AGCAβGAAGA 1740 βCTCCAGCTC CCGGACGCCC TTGACCCATG CCCTCCCAGβ CCTGTCAGAG CAGGAAGGAC 1800
AGAAGACCTC GβCTβCCAGC TGCCCCCAGC CCCCGACCTT CCTCCTGCCC CTCCTCCTCT 1860
TCCTGGCCCT TACAGTAGCC AGGCCCCGGT GGCGGTAACT GCCCCAAGGC CCCAGGGACA 1920
GAGGCCAAGβ ACTGACTTTG CCAAAAATAC AACACAGACG ATATTTAATT CACCTCAGCC 1980
TGGAGAGGCC TGGGGTGGGA CAGGGAGGGC CGGCGGCTCT βAGCAGGGGC AGGCGCAGAG 2040
GTCCCAGCCC CAGGCCTGGC CTCGCCTGCC TTTCTGCCTT TTAATTTTGT ATGAGGTCCT 2100
CAGGTCAGCT GGGAGCCAGT GTGCCCAAAA GCCATGTATT TCAGGGACCT CAGGGGCACC 2160
TCCGGCTGCC TAGCCCTCCC CCCAGCTCCC TGCACCGCCG CAGAAGCAGC CCCTCGAGGC 2220
CTACAGAGGA GβCCTCAAAβ CAACCCGCTG GAβCCCACAG CGAGCCTGTG CCTTCCTCCC 2280
CGCCTCCTCC CACTGβGACT CCCAGCAGAG CCCACCAGCC AGCCCTGGCC CACCCCCCAG 2340
CCTCCAGAGA AGCCCCGCAC GGGCTGTCTβ GGTGTCCGCC ATCCAGGGTC TGGCAGAGCC 2400
TCTGAGATGA TGCATGATGC CCTCCCCTCA GCGCAGGCTG CAGAGGCCGG CCCCACCTCC 2460
CTGCGCCCTT GAGGGβCCCC AGCGTCTβCA βGGTGACGCC TGAGACAGCA CCACTGCTGA 2520
GGAGTCTGAG GACTGTCCTC CCACAGACCC TGCAGTGAGG GGCCCTCCAT GCGCAGATGA 2580 βGGGCCACTG ACCCACCTGC GCTTCTGCTG GAGGAGGGGA AGCTGGGCCC AAAGGCCCAG 2640
GβAGGCAGCG TGGGCTCTGC CAATGTGGGC TGCCCCTCGC ACACAGGβCT CACAGβGCAG 2700
GCCTTGCTGG GβTCCAGGGC TGTTGGAGGA CCCCGAGGGC TCAGGAβCAβ CCAGGACCCG 2760
CCTGCTCCCA TCCTCACCCA GATCAGGAAC CACGGCCTCC CTβTTCACGG TGACACAGGT 2820
CAGGGCTCAG AGTGACCCTC GGCTβTCACC TβCTCACAGG GATGCTGGTG GCTGGTGAGA 2880
CCCCGCACTG CACACGGβAA TGCCTAGGTC CCTTCCCGAC CCAGCCAGCT GCACTGCAGG 2940
GCACGGGβAC CTGGATAGTT AAGGGCTTTT CCAAACATGC ATCCATTTAC TGACACTTCC 3000
TGTCCTTGTT CATGGAGAGC TGTTCGCTCC TCCCAGATGG CTTCGGAGGC CCGCAGGGCC 3060
CACCTTGGAC CCTGGTGACC TCCTGTCACT CACTGAGGCC ATCAGGGCCC TGCCCCAGGC 3120
CTGGACGGGC CCTCCTTCCC TCCTGTGCCC CAGCTGCCAG GTGGCCCTGG GGAGGGGTGG 3180
TGTGGTGTTG GGAAGGGGTC CTGCAGGGGG AGGAGGACTT GGAGGGTCTG GGββCAGCTG 3240
TCCTGAACCG ACTGACCCTG AGGAGGCCGC TTAGTGCTGC TTTGCTTTTC ATCACCβTCC 3300
CGCACAGTGG ACGGAGGTCC CCGGTTGCTG GTCAGGTCCC CATGβCTTGT TCTCTGGAAC 3360
CTGACTTTAG ATGTTTTGGG ATCAGGAGCC CCCAACACAG GCAAGTCCAC CCCATAATAA 3420
CCCTβCCAβT CCCAGGGTGG GCTGGGGACT CTGGCACAGT GATGCCGGGC GCCAGGACAG 3480
CAGCACTCCC GCTGCACACA GACGGCCTAG GGGTGGCGCT CAGACCCCAC CCTA∞CTCA 3540
TCTCTGGAAβ GGGCAGCCCT GAGTGGTCAC TGGTCAGGGC AGTGGCCAAG CCTGCTGTGT 3600
CCTTCCTCCA CAAGGTCCCC CCACCGCTCA GTGTCAGCGG GTGACGTGTG TTCTTTT6AG 3660
TCCTTGTATG AATAAAAGGC TGGAAACCTA AA 3692
Seq ID NO: C74 DNA Sequence
Nucleic Acid Accession #: BC030205.1
Coding sequence: 45.-878 1 11 21 31 41 51 i i i i i i
GTGAGCAGCC CCTAACAGGC TGTTACTTCA CTACAACTGA CGATATβATC ATCTTAATTT 60
ACTTATTTCT CTTGCTATGG GAAGACACTC AAGGATGGGG ATTCAAGGAT GGAATTTTTC 120
ATAACTCCAT ATGGCTTGAA CβAGCAGCCG GTGTGTACCA CAGAGAAGCA CGGTCTGGCA 180
AATACAAGCT CACCTACβCA βAAβCTAAGG CGGTβTβTβA ATTTGAAGGC GGCCATCTCG 240
CAACTTACAA GCAGCTAGAG GCAGCCAGAA AAATTGGATT TCATGTCTGT βCTGCTGGAT 300
GGATGGCTAA GGGCAGAGTT GGATACCCCA TTGTGAAGCC AGGGCCCAAC TGTββATTTG 360
GAAAAACTGG CATTATTGAT TATGGAATCC GTCTCAATAG GAGTβAAAβA TGGGATGCCT 420
ATTGCTACAA CCCACACGCA AAGGAGTGTβ GTGGCGTCTT TACAGATCCA A&βCAAATTT 480
TTAAATCTCC ACGCTTCCCA AATGAGTACG AAGATAACCA AATCTGCTAG TGGCACATTA 540
GACTCAAGTA TGGTCAGCGT ATTCACCTGA GTTTTTTAGA TTTTGACCTT GAAGATGACC 600
CAGGTTGCTT GGCTGATTAT βTTβAAATAT ATGACAGTTA CGATGATGTC CATGGCTTTG 660
TGGGAAGATA CTGTGGAGAT GAGCTTCCAG ATGACATCAT CAGTACAGGA AATGTCATβA 720
CCTTGAAGTT TCTAAGTGAT GCTTCAGTβA CAGCTGGAGG TTTCCAAATC AAATATGTTG 780
CAATGGATCC TGTATCCAAA TCCAGTCAAG GAAAAAATAC AAGTACTACT TCTACTGGAA 840
ATAAAAACTT TTTAGCTGGA AGATTTAGCC ACTTATAAAA AAAAAAAAAG GATGATCAAA 900
ACACACAβTβ TTTATGTTGG AATCTTTTGG AACTCCTTTG ATCTCACT6T TATTATTAAC 960
ATTTATTTAT TATTTTTCTA AATGTGAAAG CAATACATAA TTTAGGGAAA ATTGGAAAAT 1020
ATAGGAAACT TTAAACGAGA AAATGAAACC TCTCATAATC CCACTGCATA GAAATAACAA 1080
GCCTTAACAT TTTCATATTT TTTTCTTTCA CTCATTTTTC TATTTGTGGT ATATGTATAT 1140
ATGTACCTAT ATGTATTTGC ATTTGAAATT TTGGAATCCT GCTCTATβTA CAβTTTTGTA 1200
TTATACTTTT TAAATCTTGA ACTTTATAAA CATTTTCTGA AATCATTGAT TATTCTACAA 1260
AAACATGATT TTAAACAGCT GTAAAATATT CTATGATATG AATGTTTTAT GCATTATTTA 1320
AGCCTGTCTC TATTGTTGGA ATTTCAGGTC ATTTTCATAA ATATTGTTGC AATAAATATC 1380
CTTGAACACA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 1430
Seq ID NO: C75 DNA Sequence
Nucleic Acid Accession ff: NM_001982.1
Coding sequence: 199..4227
1 11 21 31 41 51
I I I I I I
CTCTCACACA CACACACCCC TCCCCTGCCA TCCCTCCCCG GACTCCGGCT CCGGCTCCGA 60 TTGCAATTTG CAACCTCCGC TGCCGTCGCC GCAβCAGCCA CCAATTCGCC AGCβGTTCAG 120 GTGGCTCTTG CCTCGATGTC CTAGCCTAGG GGCCCCCGGG CCGGACTTββ CTGGGCTCCC 180
TTCACCCTCT GCGGAGTCAT GAGGGCGAAC GACGCTCTGC AGGTGCTGGG CTTGCTTTTC 240
AGCCTGGCCC GGGGCTCCGA GGTGGGCAAC TCTCAGGCAG TGTβTCCTββ GACTCTGAAT 300
GGCCTβAGTG TGACCGGCGA TGCTGAGAAC CAATACCAGA CACTGTACAA GCTCTACGAG 360
AGGTβTβAGG TGGTGATGGG GAACCTTGAG ATTGTGCTCA CGGGACACAA TGCCGACCTC 420
TCCTTCCTGC AGTGGATTCG AGAAGTGACA GGCTATGTCC TCGTGGCCAT GAATGAATTC 480
TCTACTCTAC CATTGCCCAA CCTCCGCGTG GTGCGAGGGA CCCAGGTCTA CGATGGGAAG 540
TTTGCCATCT TCGTCATGTT GAACTATAAC ACCAACTCCA GCCACGCTCT GCGCCAGCTC 600
CGCTTGACTC AGCTCACCβA GATTCTGTCA GGGGGTGTTT ATATTGAGAA βAACGATAAG 660
CTTTGTCACA TGGACACAAT TGACTGGAGβ GACATCGTβA GGGACCGAGA TGCTGAGATA 720
GTβGTGAAGG ACAATGGCAG AAGCTGTCCC CCCTGTCATG AGGTTTGCAA GGGGCGATGC 780
TGGGGTCCTG GATCAGAAGA CTGCCAGACA TTGACCAAGA CCATCTGTGC TCCTCAGTGT 840
AATGGTCACT GCTTTGGGCC CAACCCCAAC CAGTGCTGCC ATGATGAGTG TGCCGGGGGC 900
TβCTCAGGCC CTCAGGACAC AGACTGCTTT GCCTGCCGGC ACTTCAATGA CAGTGGAGCC 960
TGTGTACCTC GCTGTCCACA GCCTCTTGTC TACAACAAβC TAACTTTCCA CCTGGAACCC 1020
AATCCCCACA CCAAGTATCA GTATGGAβGA GTTTGTGTAβ CCAGCTGTCC CCATAACTTT 1080
GTGGTβGATC AAACATCCTG TGTCAGGGCC TGTCCTCCTG ACAAGATGβA AGTAGATAAA 1140
AATGGGCTCA AGATGTGTGA GCCTTGTGGG GGACTATGTC CCAAAGCCTG TGAGGGAACA 1200
GGCTCTGGGA GCCGCTTCCA GACTGTGGAC TCGAGCAACA TTGATGGATT TGTβAACTGC 1260
ACCAAGATCC TGGGCAACCT GGACTTTCTG ATCACCGGCC TCAATGGAGA CCCCTGGCAC 1320
AAGATCCCTG CCCTGGACCC AGAGAAGCTC AATGTCTTCC GGACAGTACG GGAGATCACA 1380
GGTTACCTGA ACATCCAGTC CTGGCCβCCC CACATβCACA ACTTCAGTβT TTTTTCCAAT 1440
TTGACAACCA TTGGAGGCAG AAGCCTCTAC AACCGGGGCT TCTCATTGTT GATCATGAAG 1500
AACTTGAATG TCACATCTCT GGGCTTCCGA TCCCTGAAGG AAATTAGTGC TGGGCGTATC 1560
TATATAAGTG CCAATAGGCA GCTCTGCTAC CACCACTCTT TGAACTGGAC CAAGGTGCTT 1620
CGGGGGCCTA CGGAAGAGCG ACTAGACATC AAGCATAATC G6CCGCGCAG AGACTGCGTG 1680
GCAGAGGGCA AAGTGTGTGA CCCACTGTGC TCCTCTβGGβ GATGCTGGGG CCCAGGCCCT 1740
GGTCAGTGCT TβTCCTGTCβ AAATTATAGC CGAGβAβGTG TCTGTGTGAC CCACTGCAAC 1800
TTTCTβAATG GGGAGCCTCG AGAATTTGCC CATGAGGCCG AATGCTTCTC CTGCCACCCG 1860
GAATGCCAAC CCATGGGGGG CACTGCCACA TGCAATGGCT CGβGCTCTGA TACTTGTGCT 1920
CAATGTGCCC ATTTTCGAGA TGGGCCCCAC TGTGTGAGCA GCTGCCCCCA TGGAGTCCTA 1980
GGTGCCAAGG GCCCAATCTA CAAGTACCCA GATGTTCAGA ATGAATGTCG GCCCTGCCAT 2040
GAGAACTβCA CCCAGGGGTG TAAAGGACCA GAGCTTCAAG ACTGTTTAGG ACAAACACTG 2100
GTGCTGATCG βCAAAACCCA TCTGACAATG GCTTTGACAG TGATAGCAβG ATTGGTAGTG 2160
ATTTTCATGA TGCTGGGCGG CACTTTTCTC TACTGGCGTG GGCGCCGGAT TCAGAATAAA 2220
AGGGCTATGA GGCGATACTT GGAACGGGGT GAGAGCATAG AGCCTCTGGA CCCCAGTGAG 2280
AAGGCTAACA AAGTCTTGGC CAGAATCTTC AAAGAGACAG AGCTAAGGAA GCTTAAAGTG 2340
CTTGGCTCGG GTGTCTTTGG AACTGTGCAC AAAGGAGTGT ββATCCCTGA GGGTGAATCA 2400
ATCAAGATTC CAGTCTGCAT TAAAGTCATT GAGGACAAGA GTβGACGGCA GAGTTTTCAA 2460
GCTGTGACAG ATCATATGCT GGCCATTGGC AGCCTGGACC ATGCCCACAT TGTAAGGCTG 2520
CTGGGACTAT GCCCAGGGTC ATCTCTGCAG CTTGTCACTC AATATTTGCC TCTGGGTTCT 2580
CTGCTGGATC ATGTGAGACA ACACCGβGGG GCACTGGGGC CACAGCTGCT GCTCAACTGG 2640
GGAGTACAAA TTGCCAAGGG AATGTACTAC CTTGAGGAAC ATGGTATGβT GCATAGAAAC 2700
CTGGCTGCCC GAAACGTGCT ACTCAAGTCA CCCAGTCAGG TTCAGGTGGC AGATTTTGGT 2760
GTGGCTGACC TGCTCCCTCC TβATGATAAG CAGCTGCTAT ACAGTGAGGC CAAGACTCCA 2820
ATTAAGTGGA TGGCCCTTGA GAGTATCCAC TTTGGGAAAT ACACACACCA GAGTGATGTC 2880
TGGAGCTATG GTGTGACAGT TTGGGAGTTG ATGACCTTCG GGGCAGAGCC CTATGCAGGG 2940
CTACGATTGG CTGAAGTACC AGACCTGCTA GAGAAGGGGG AGCGGTTGGC ACAGCCCCAG 3000
ATCTGCACAA TTGATGTCTA GATGCTGATG GTCAAGTGTT GGATGATTGA TGAGAACATT 3060
CGCCCAACCT TTAAAGAACT AGCCAATGAG TTCACCAGGA TβGCCCGAGA CCCACCACGG 3120
TATCTGGTCA TAAAGAGAGA GAGTGGβCCT GGAATAGCCC CTGGGCCAGA GCCCCATGGT 3180
CTGACAAACA AGAAGCTAGA GGAAβTAGAG CTGGAGCCAG AACTAGACCT AGACCTAGAC 3240
TTGGAAGCAG AGGAGGACAA CCTGGCAACC ACCACACTGG GCTCCGCCCT CAGCCTACCA 3300
GTTGGAACAC TTAATCGGCC ACGTGGGAGC CAGAGCCTTT TAAGTCCATC ATCTGGATAC 3360
ATGCCCATGA ACCAGGGTAA TCTTGGGGββ TCTTGCCAGG AGTCTGCAGT TTCTGGGAGC 3420
AGTβAACCGT GCCCCCGTCC AGTCTCTCTA CACCCAATGC CACβGGGATG CCTGGCATCA 3480
GAβTCATCAG AGGGGCATGT AACAGGCTCT GAGGCTGAGC TCCAGGAGAA AGTGTCAATG 3540
TGTAβAAGCC GGAGCAGGAG CCGGAGCCCA CGGCCACGCG GAGATAβCGC CTACCATTCC 3600
CAGCβCCACA GTCTGCTGAC TCCTGTTACC CCACTCTCCC CACCCGGGTT AGAGGAAGAG 3660
GATGTCAACG GTTATGTCAT GCCAGATACA CACCTCAAAG GTACTCCCTC CTCCCGGGAA 3720
GGCACCCTTT CTTCAGTGβG TCTCAGTTCT GTCCTGGGTA CTGAAGAAGA AGATGAAGAT 3780
GAGGAGTATG AATACATGAA CCGGAGGAGA AGGCACAGTC CACCTCATCC CCCTAGGCCA 3840
AGTTCCCTTG AGGAGCTGGG TTATGAGTAC ATGGATGTGG GβTCAGACCT CAGTGCCTCT 3900
CTC∞CAGCA CACAGAGTTG CCCACTCCAC CCTGTACCCA TCATGCCCAC TGCAGGCACA 3960
ACTCCAGATβ AAGACTATGA ATATATGAAT CGGCAACGAG ATGGAGGTGG TCCTGGGβGT 4020
GATTATGCAG CCATGGGGGC CTGCCCAGCA TCTGAGCAAG GGTATGAAGA GATGAGAβCT 4080
TTTCAGGGGC CTGGACATCA βGCCCCCCAT GTCCATTATG CCCGCCTAAA AACTCTACGT 4140
AGCTTAGAGG CTACAβACTC TGCCTTTGAT AACCCTGATT ACTGGCATAG CAGGCTTTTC 4200
CCCAAGGCTA ATGCCCAGAG AACGTAACTC CTGCTCCCTG TGβCACTCAG GGAGCATTTA 4260
ATGGCAGCTA GTGCCTTTAG AGGGTACCGT CTTCTCCCTA TTCCCTCTCT CTCCCAGGTC 4320
CCAGCCCCTT TTCCCCAGTC CCAGACAATT CCATTCAATC TTTGGAGGCT TTTAAACATT 4380
TTGACACAAA ATTCTTATGG TATGTAGCCA GCTGTGCACT TTCTTCTCTT TCCCAACCCC 4440
AGGAAAGGTT TTCCTTATTT TGTGTGCTTT CCCAGTCCCA TTCCTCAGCT TCTTCACAGG 4500
CACTCCTGGA GATATGAAGG ATTACTCTCC ATATCCCTTC CTCTCAGGCT CTTGACTACT 4560
TGGAACTAGG CTCTTATGTG TGCCTTTGTT TCCCATCAGA CTGTCAAβAA GAGGAAAGGG 4620
AGGAAACCTA GCAGAGGAAA GTGTAATTTT GGTTTATGAC TCTTAACCCC CTAGAAAGAC 4680
AGAAGCTTAA AATCTGTGAA GAAAGAGGTT AGGAGTAGAT ATTGATTACT ATCATAATTC 4740
AGCACTTAAC TATGAGCCAG GCATCATACT AAACTTCACC TACATTATCT CACTTAGTCC 4800
TTTATCATCC TTAAAACAAT TCTGTGACAT ACATATTATC TCATTTTACA CAAAGGGAAβ 4860
TCGGβCATβG TGGCTCATGC CTGTAATCTC AGCACTTTGG GAGGCTGAGG CAGAAGGATT 4920
ACCTGAGGCA AGGAGTTTGA GACCAGCTTA GCCAACATAG TAAGACCCCC ATCTC 4975
Seq ID NO: C76 DNA Sequence Nucleic Acid Accession #: NM_001216.1 Coding sequence: 43..1422
1 11 21 31 41 51 I 1 | 1 | 1 | 1 | 1 | 1 GCCCGTACAC ACCGTGTGCT GGGACACCCC ACAGTCAGCC GCATGGCTCC CCTGTGCCCC 60
AGCCCCTGGC TCCCTCTGTT GATCCCGβCC CCTGCTCCAG GCCTCACTGT GCAACTGCTG 120
CTGTCACTGC TGCTTCTGAT GCCTGTCCAT CCCCAGAGGT TGCCCCGGAT GCAGGAGGAT 180
TCCCCCTTGG GAGGAGGCTC TTCTGGGGAA GATβACCCAC TGGGCGAGGA GGATCTGCCC 240
AGTGAAGAGG ATTCACCCAG AGAGGAGGAT CCACCCGGAG AGGAGGATCT ACCTGGAGAG 300
GAGGATCTAC CTGGAGAGGA GGATCTACCT GAAGTTAAGC CTAAATCAGA AGAAβAββGC 360
TCCCTGAAGT TAGAGGATCT ACCTACTGTT GAGGCTCCTG GAGATCCTCA AGAACCCCAG 420
AATAATGCCC ACAGGGACAA AGAAGGGGAT GACCAGAGTC ATTGGCGCTA TGGAGGCGAC 480
CCGCCCTGGC CCCGGGTGTC CCCAGGCTGC GCGGGCCGCT TCCAGTCCCC GβTβGATATC 540
CGCCCCCAGC TCGCCGCCTT CTGCCCGGCC CTGCGCCCCC TGGAACTCCT GβGCTTCCAG 600
CTGCCGCCGC TCCCAGAACT GCGCCTGCGC AACAATGGCC ACAGTGTGCA ACTGACCCTG 660
CCTCCTGGGG TAGAGATGGC TCTGGGTCCC GGGCGGGAGT ACCGGGCTCT GCAGCTGCAT 720
CTGCACTGGG GGGCTCCAGG TCGTCCGGGC TCGGAGCACA CTGTGGAAGG CCACCβTTTC 780
CCTGCCGAGA TCCACGTGGT TCACCTCACC ACCGCCTTTG CCAGAβTTβA CβAβGCCTTG 840
GGGCGCCCGG βAGGCCTGGC CGTGTTGGCC GCCTTTCTGG AGGAGGGCCC βGAAGAAAAC 900
AGTGCCTATG AGCAGTTGCT GTCTCGCTTG GAAGAAATCG CTGAGGAAGG CTCAGAβACT 960
CAGGTCCCAG GACTGGACAT ATCTGCACTC CTGCCCTCTG ACTTCAGCCβ CTACTTCCAA 1020
TATGAGGGGT CTCTCACTAC ACCGCCCTGT GCCCAGGGTG TCATCTGGAC TGTGTTTAAC 1080
CAGACACTGA TGCTGAGTGC TAAGCAGCTC CACACCCTCT CTGACACCCT GTGGGGACCT 1140
GGTGACTCTC GGCTACAGCT βAACTTCCGA GCGACGCAGC CTTTGAATGG GCGAGTGATT 1200
GAGGCCTCCT TCCCTGCTGG AGTGGACAGC AGTCCTCGGG CTGCTGAGCC AGTCCAGCTG 1260
AATTCCTGCC TGGCTGCTGG TGACATCCTA GCCCTGGTTT TTGGCCTCCT TTTTGCTGTC 1320
ACCAGCGTCG CGTTCCTTβT GCAGATGAGA AGGCAGCACA GAAGGGGAAC CAAAGGGGGT 1380
GTGAGCTACC GCCCAGCAGA GβTAGCCGAβ ACTGGAGCCT AGAGGCTGGA TCTTGGAGAA 1440
TGTGAGAAGC CAGCCAGAGG CATCTGAGGG GGAGCCGGTA ACTGTCCTGT CCTGCTCATT 1500
ATGCCACTTC CTTTTAACTG CCAAGAAATT TTTTAAAATA AATATTTATA AT 1552
Seq ID NO: C7 DNA Sequence
Nucleic Acid Accession #: NM_004207.1
Coding sequence: 63..1460
11 21 31
GGCGAGAGGC GGGCTGAGGC GGCCCAGCGG CGGCAGGTGA GGCGGAACCA ACCCTCCTGG 60
CCATGGGAGG GGCCGTGGTG GACGAGGGCC CCACAGGCGT CAAGGCCCCT GACGGCGGCT 120
GGGGCTGGβC CGTGCTCTTC GGCTGTTTCG TCATCACTβG CTTCTCCTAC GCCTTCCCCA 180
AGGCCGTCAG TGTCTTCTTC AAGGAGCTCA TACAGGAGTT TGGGATCGGC TACAGCGACA 240
CAGCCTGβAT CTCCTCCATC CTGCTGGCCA TGCTCTACGG GACAGGTCCG CTCTGCAGTG 300
TGTGCGTGAA CCGCTTTGGC TGCCG6CCCG TCATβCTTβT GGGGGGTCTC TTTGCGTCGC 360
TGGGCATGGT GGCTGCGTCC TTTTGCCGGA eCATCATCCA GGTCTACCTC ACCACTGGGG 420
TCATCACGGG GTTGββTTTβ GCACTCAACT TCCAGCCCTC GCTCATCATβ CTβAACCβCT 480
ACTTCAGCAA GCGGCGCCCC ATββCCAACG GGCTGGCeβC AβCAGGTAβC CCTβTCTTCC 540
TGTGTGCCCT GAGCCCGCTG GGGCAGCTβC TβCAGβACCβ CTAceecTββ CGGGGCGGCT 600
TCCTCATCCT GGGCGGCCTG CTGCTCAACT GCTGCGTGTG TGCCGCACTC ATGAGGCCCC 660
TGGTGGTCAC GGCCCAGCCG GGCTCGGGGC CGCCGCGACC CTCCCGGCGC CTGCTAGACC 720
TGAGCGTCTT CCGβGACCGC GGCTTTGTGC TTTACGCCGT GGCCGCCTCG GTCATGGTGC 780
TGGGGCTCTT CGTCCCGCCC GTGTTCGTGG TGAGCTACGC CAAGGACCTG GGCGTGCCCG 840
ACACCAAGGC CGGCTTCCTG CTCACCATCC TGGGCTTCAT TGACATCTTC GCGCGGCCGG 900
CCGCGGGCTT CGTGGCGGGG CTTGβGAAGβ TGCGGCCCTA CTCCGTCTAC CTCTTCAGCT 960
TCTCCATGTT CTTCAACGGC CTCGCGGACC TGGCGGGCTC TACGGCGGGC βACTACGGCG 1020 βCCTCGTGGT CTTCTGCATC TTCTTTGGCA TCTCCTACGG CATGGTGGGG GCCCTGCAGT 1080
TCGAGGTGCT CATGGCCATC GTGβGCACCC ACAAGTTCTC CAGTGCCATT GGCCTG6TGC 1140
TGCTGATGβA GGCGGTGGCC GTGCTCGTCG GGCCCCCTTC GGGAGGCAAA CTCCTGGATG 1200
CGACCCACGT CTACATGTAC GTGTTCATCC TGGCGGGGGC CGAGGTGCTC ACCTCCTCCC 1260
TGATTTTGCT GCTGGβCAAC TTCTTCTGCA TTAGGAAGAA GCCCAAAGAG CCACAGCCTG 1320
AGGTGGCGGC CGCG6AGGAG GAGAAGCTCC ACAAGCCTCC TGCAGACTCβ GGGGTGGACT 1380
TGCGGGAGβT GGAGCATTTC CTGAAGβCTβ AGCCTGAGAA AAACGGββAG GTCGTTCACA 1440
CCCCGGAAAC AAGTGTCTGA GTGGCTGGGC GGGGCCGGCA GGCACAGGGA GβAβGTACAG 1500
AAGCCGGCAA CGCTTGCTAT TTATTTTACA AACTGGACTG GCTCAGGCAG GGCCACGGCT 1560
GββCTCCAGC TGCCGGCCCA GCGGATCGTC GCCCGATCAG TGTTTTGAGG GGGAAGGTGG 1620
CGGGGTGGGA ACCGTGTCAT TCCAGAGTGG ATCTGCGGTG AAGCCAAGCC GCAAGGTTAC 1680
AAGGCATCCT CACCAGGGGC CGCGCCTGCT GCTCCCAGGT GGCCTGCGGC CACTGCTATG 1740
CTCAAGGACC TGβAAACCCA TGCTTCGAGA CAACGTGACT TTAATGGGAG GGTGGGTGGG 1800
CCGCAGACAG βCTGGCAGGG CAGGTGCTGC GTGGGGCCCT CTCCAGCCCG TCCTACCCTG 1860
GGCTCACATG GGGCCTGTGC CCACCCCTCT TGAGTGTCTT GGGGACAGCT CTTTCCACCC 1920
CTGGAAGATG GAAATAAACC TGCGTGTGGG TGGAβTGTTC TCGTGCCGAA TTCAAAAAGC 1980
TT 1982
Seq ID NO: C78 DNA Sequence
Nucleic Acid Accession ft: NM_0003S8.1
Coding sequence: 48..2099 1 11 21 31 41 51 i i i i i i
GCTTGCCCGT CGGTCGCTAG CTCGCTCGGT GCGCGTCGTC CCGCTCCATG GCGCTCTTCG 60
TGCGGCTGCT GGCTCTCGCC CTGGCTCTGG CCCTGGGCCC CGCCGCGACC CTGGCGGGTC 120
CCGCCAAβTC GCCCTACCAG CTGGTGCTGC AGCACAGCAG GCTCCGGGGC CGCCAGCACG 180
GCCCCAACGT GTGTGCTGTG CAGAAGGTTA TTGGCACTAA TAGGAAGTAC TTCACCAACT 240 GCAAGCAGTG GTACCAAAGG AAAATCTGTG GCAAATCAAC AGTCATCAGC TACGAGTGCT 300
GTCCTGGATA TGAAAAGGTC CCTGGGGAGA AGGGCTGTCC AGCAGCCCTA CCACTCTCAA 360
ACCTTTACGA GACCCTβGGA GTCGTTGGAT CCACCACCAC TCAGCTGTAC ACGGACCGCA 420
CGGAGAAGCT GAGGCCTGAG ATGGAGGGGC CCGGCAGCTT CACCATCTTC GCCCCTAGCA 480
ACGAGGCCTβ GGCCTCCTTG CCAGCTGAAβ TGCTGGACTC CCTGGTCAGC AATCTCAACA 540
TTGAGCTGCT CAATGCCCTC CGCTACCATA TGGTGGGCAG GCGAGTCCTG ACTGATGAGC 600
TGAAACACGG CATGACCCTC ACCTCTATGT ACCAGAATTC CAACATCCAG ATCCACCACT 660
ATCCTAATGG GATTGTAACT GTGAACTGTG CCCGGCTCCT GAAAGCCGAC CACCATGCAA 720
CCAACGGGGT GGTGCACCTC ATCGATAAGG TCATCTCCAC CATCACCAAC AACATCCAGC 780
AGATCATTGA GATCGAGGAC ACCTTTGAGA CCCTTCGGβC TGCTGTGGCT GCATCAGGGC 840
TCAACACGAT GCTTGAAGGT AACGGCCAGT ACACGCTTTT GGCCCCGACC AATGAGGCCT 900
TCGAGAAβAT CCCTAGTGAG ACTTTGAACC GTATCCTGGG CGACCCAβAA GCCCTGAGAG 960
ACCTGCTβAA CAACCACATC TTGAAGTCAG CTATGTβTGC TGAAGCCATC GTTGCGGGGC 1020
TGTCTGTAGA GACCCTGβAG GGCACGACAC TGGAGGTGGG CTGCAGCGGG GACATGCTCA 1080
CTATCAACGG GAAGGCGATC ATCTCCAATA AAGACATCCT AGCCACCAAC GGGGTGATCC 1140
ACTACATTGA TGAGCTACTC ATCCCAGACT CAGCCAAGAC ACTATTTGAA TTGGCTGCAG 1200
AGTCTGATGT GTCCACAGCC ATTβACCTTT TCAGACAAGC CGGCCTCGGC AATCATCTCT 1260
CTGGAAGTGA GCGGTTGACC CTCCTGGCTC CCCTGAATTC TGTATTCAAA GATGGAACCC 1320
CTCCAATTGA TGCCCATACA AGGAATTTGC TTCGGAACCA CATAATTAAA GACCAβCTGG 1380
CCTCTAAGTA TCTGTACCAT GGACAGACCC TGGAAACTCT GGGCGGCAAA AAACTGAGAG 1440
TTTTTGTTTA TCGTAATAβC CTCTGCATTG AGAACAGCTG CATCGCGGCC CACGACAAGA 1500
GGGGGAGGTA CGGGACCCTG TTCACGATGG ACCGGGTGCT GACCCCCCCA ATGGGGACTG 1560
TCATGβATβT CCTβAAGGGA GACAATCGCT TTAGCATβCT GGTAGCTGCC ATCCAGTCTG 1620
CAGGACTGAC GGAGACCCTC AACCGGGAAG GAGTCTACAC AGTCTTTGCT CCCACAAATG 1680
AAGCCTTCCG AGCCCTGCCA CCAAGAGAAC GGAGCAGACT CTTGGGAGAT GCCAAGGAAC 1740
TTGCCAACAT CCTGAAATAC CACATTGGTG ATGAAATCCT GβTTAGCGGA GGCATCGGGβ 1800
CCCTGGTGCG GCTAAAGTCT CTCCAAGGTG ACAAGCTGGA AGTCAGCTTG AAAAACAATC 1860
TGGTβAGTGT CAACAAGGAG CCTGTTGCCG AGCCTGACAT CATGGCCACA AATGGCGTGG 1920
TCCATGTCAT CACCAATGTT CTGCAGCCTC CAGCCAACAG ACCTCAGGAA AGAGGGGATG 1980
AACTTGCAGA CTCTGCGCTT GAGATCTTCA AACAAGCATC AGCGTTTTCC AGGGCTTCCC 2040
AGAGGTCTGT GCGACTAGCC CCTGTCTATC AAAAGTTATT AGAGAGGATG AAGCATTAGC 2100
TTGAAGCACT ACAGGAGGAA TGCACCACGG CAGCTCTCCG CCAATTTCTC TCAGATTTCC 2160
ACAGAGACTG TTTβAATβTT TTCAAAACCA AGTATCACAC TTTAATGTAC ATGGGCCGCA 2220
CCATAATGAG ATGTGAGCCT TGTGCATGTG GGGGAGGAGβ βAGAGAGATG TACTTTTTAA 2280
ATCATGTTCC CCCTAAACAT GGCTGTTAAC CCACTGCATG CAGAAACTTG GATGTCACTG 2340
CCTGACATTC ACTTCCAGAG AGGACCTATC CCAAATGTGG AATTGACTGC CTATGCCAAG 2400
TCCCTGGAAA AGGAGCTTCA GTATTGTGGG GCTCATAAAA CATGAATCAA GCAATCCAGC 2460
CTCATGGGAA GTCCTGGCAC AGTTTTTGTA AAGCCCTTGC ACAGCTGGAG AAATGGCATC 2520
ATTATAAGCT ATGAGTTGAA ATGTTCTGTC AAATGTGTCT CACATCTACA CGTGGCTTGG 2580
AGβCTTTTAT GGGGCCCTGT CCAGβTAGAA AAGAAATGGT ATGTAGAGCT TAGATTTCCC 2640
TATTGTGACA GAGCCATGGT βTGTTTGTAA TAATAAAACC AAAGAAACAT A 2691
Seq ID NO : C79 DNA Sequence
Nucleic Acid Accession # : NM_006536 .2
Coding sequence : 109 . .2940
1 11 21 31 41 51
I I I I I I
ACCTAAAACC TTGCAAGTTC AGGAAGAAAC CATCTGCATC CATATTGAAA ACCTGACACA 60
ATGTATGCAG CAGGCTCAGT GTGAGTGAAC TGGAGGCTTC TCTACAACAT GACCCAAAGG 120
ACCATTGCAG GTCCTATTTG CAACCTGAAG TTTGTGACTC TCCTGGTTGC CTTAAGTTCA 180
GAACTCCCAT TCCTGGGAGC TGGAGTACAG CTTCAAGACA ATGGGTATAA TGGATTGCTC 240
ATTGCAATTA ATCCTCAGGT ACCTGAGAAT CAGAACCTCA TCTCAAACAT TAAGGAAATG 300
ATAACTGAAβ CTTCATTTTA CCTATTTAAT GCTACCAAGA GAAGAGTATT TTTCAGAAAT 360
ATAAAGATTT TAATACCTGC CACATGβAAA GCTAATAATA ACAGCAAAAT AAAACAAGAA 420
TCATATβAAA AGGCAAATGT CATAGTGACT GACTGGTATG GGGCACATGG AGATGATCCA 480
TACACCCTAC AATACAGAGG GTGTGβAAAA GAGGGAAAAT ACATTCATTT CACACCTAAT 540
TTCCTACTGA ATGATAACTT AACAGCTGGC TACGGATCAC GAGGCCGAGT GTTTGTCCAT 600
GAATGGGCCC ACCTCCGTTG GGGTGTGTTC GATGAGTATA ACAATGACAA ACCTTTCTAC 660
ATAAATGGGC AAAATCAAAT TAAAGTGACA AGGTGTTCAT CTGACATCAC AGGGATTTTT 720
GTGTGTGAAA AAGGTCCTTG CCCCCAAGAA AACTGTATTA TTAGTAAGCT TTTTAAAβAA 780
GGATGCACCT TTATCTACAA TAGCACCCAA AATGCAACTG CATCAATAAT GTTCATGCAA 840
AGTTTATCTT CTGTGβTTGA ATTTTGTAAT GCAAGTACCC ACAACCAAGA AGCACCAAAC 900
CTACAGAACC AGATβTGCAG CCTCAGAAGT GCATGGGATG TAATCACAGA CTCTGCTGAC 960
TTTCACCACA GCTTTCCCAT GAATGGGACT GAGCTTCCAC CTCCTCCCAC ATTCTCGCTT 1020
GTACAβGCTG GTGACAAAGT GGTCTGTTTA GTGCTGGATG TGTCCAGCAA GATGGCAGAG 1080
GCTGACAGAC TCCTTCAACT ACAACAAGCC GCAGAATTTT ATTTGATGCA GATTGTTGAA 1140
ATTCATACCT TCGTGGβCAT TGCCAGTTTC GACAGCAAAG GAGAGATCAG AβCCCAGCTA 1200
CACCAAATTA ACAGCAATGA TGATCGAAAG TTGCTGGTTT CATATCTGCC CACCACTGTA 1260
TCAGCTAAAA CAGACATCAG CATTTGTTCA GGGCTTAAGA AAGGATTTGA GGTGGTTGAA 1320
AAACTGAATβ GAAAAGCTTA TGGCTCTGTG ATGATATTAG TGACCAGCGG AGATGATAAG 1380
CTTCTTGGCA ATTGCTTACC CACTGTGCTC AGCAGTGGTT CAACAATTCA CTCCATTGCC 1440
CTGβGTTCAT CTGCAGCCCC AAATCTGGAG GAATTATCAC GTCTTACAGG AGGTTTAAAG 1500
TTCTTTGTTC CAGATATATC AAACTCCAAT AGCATGATTβ ATβCTTTCAG TAGAATTTCC 1560
TCTGGAACTG GAGACATTTT CCAGCAACAT ATTCAβCTTβ AAAβTACAGG TGAAAATGTC 1620
AAACCTCACC ATCAATTGAA AAACACAGTG ACTGTGGATA ATACTGTGGG CAACGACACT 1680
ATGTTTCTAβ TTACGTGGCA GGCCAGTGGT CCTCCTGAGA TTATATTATT TGATCCTGAT 1740
GGACGAAAAT AC ACACAAA TAATTTTATC ACCAATCTAA CTTTTCGGAC AGCTAGTCTT 1800
TGGATTCCAG GAACAGCTAA GCCTGGGCAC TGGACTTACA CCCTGAACAA TACCCATCAT 1860
TCTCTGCAAβ CCCTβAAAGT GACAGTGACC TCTCGCGCCT CCAACTCAGC TGTGCCCCCA 1920
GCCACTGTGG AAGCCTTTGT GGAAAGAGAC AGCCTCCATT TTCCTCATCC TGTGATGATT 1980
TATGCCAATG TGAAACAGGG ATTTTATCCC ATTCTTAATG CCACTGTCAC TGCCACAGTT 2040
GAGCCAGAGA CTGGAGATCC TGTTACGCTG AGACTCCTTG ATGATGGAGC AGGTGCTGAT 2100 GTTATAAAAA ATGATGGAAT TTACTCGAGG TATTTTTTCT CCTTTGCTGC AAATGGTAGA 2160
TATAβCTTGA AAGTGCATGT CAATCACTCT CCCAGCATAA GCACCCCAGC CCACTCTATT 2220
CCAGGGAGTC ATGCTATGTA TGTACCAGGT TACACAGCAA ACGGTAATAT TCAGATGAAT 2280
GCTCCAAGGA AATCAGTAGG CAGAAATGAG GAGGAGCGAA AGTGGGGCTT TAGCCGAGTC 2340
AGCTCAGGAG GCTCCTTTTC AGTGCTGGGA GTTCCAGCTG GCCCCCACCC TGATGTGTTT 2400
CCACCATGCA AAATTATTβA CCTGGAAGCT GTAAAAGTAG AAGAGGAATT GACCCTATCT 2460
TGGACAGCAC CTGGAGAAGA CTTTGATCAG GGCCAGGCTA CAAGCTATGA AATAAGAATG 2520
AGTAAAAGTC TACAGAATAT CCAAGATGAC TTTAACAATG CTATTTTAGT AAATACATCA 2580
AAGCGAAATC CTCAGCAAGC TGGCATCAGG GAGATATTTA CGTTCTCACC CCAGATTTCC 2640
ACGAATGGAC CTGAACATCA GCCAAATGGA GAAACACATG AAAGCCACAG AATTTATGTT 2700
GCAATACGAG CAATGGATAG GAACTCCTTA CAGTCTGCTG TATCTAACAT TGCCCAGGCG 2760
CCTCTGTTTA TTCCCCCCAA TTCTGATCCT GTACCTGCCA GAGATTATCT TATATTGAAA 2820
GGAGTTTTAA CAGCAATGGG TTTGATAGGA ATCATTTGCC TTATTATAGT TGTβACACAT 2880
CATACTTTAA GCAGGAAAAA GAGAGCAGAC AAGAAAGAGA ATGGAACAAA ATTATTATAA 2940
ATAAATATCC AAAGTGTCTT CCTTCTTAGA TATAAGACCC ATGGCCTTCG ACTACAAAAA 3000
CATACTAACA AAGTCAAATT AACATCAAAA CTGTATTAAA ATGCATTGAG TTTTTCTACA 3060
ATACAGATAA βATTTTTACA TGGTAGATCA ACAATTCTTT TTGGGGGTAG ATTAGAAAAC 3120
CCTTACACTT TGGCTATGAA CAAATAATAA AAATTATTCT TTAAAGTAAT GTCTTTAAAG 3180
GCAAAGGGAA GGGTAAAGTC GGACCAGTGT CAAGGAAAGT TTGTTTTATT GAGGTGGAAA 3240
AATAGCCCCA AGCAGAGAAA AGGAGGGTAG GTCTGCATTA TAACTGTCTG TGTGAAGCAA 3300
TCATTTAGTT ACTTTGATTA ATTTTTCTTT TCTCCTTATC TGTGCAGTAC AGGTTGCTTG 3360
TTTACATGAA GATCATGCTA TATTTTATAT ATGTAGCCCC TAATGCAAAG CTCTTTACCT 3420
CTTGCTATTT TGTTATATAT ATTTCAGATG ACATCTCCCT GCTAATGCTC AGAGATCTTT 3480
TTTCACTGTA AGAGGTAACC TTTAACAATA TGGβTATTAC CTTTGTCTCT TCATACCGGT 3540
TTTATGACAA AGGTCTATTG AATTTATTTG TNTGTAA6TT TCTACTCCCA TCAAAGCAGC 3600
TTTCTAAGTT TATTGCCTTG GGTTATTATG GAATGATAGT TATAGCCCCN TATAATGCCT 3660
TACCTAGβAA A 3671
Seq ID NO: C80 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 1..1413
1 11 21 31 41 51
1 1 1 1 | 1 | 1 | 1 J 1 ATGAAGTTTC TTCTAATACT GCTCCTGCAG GCCACTGCTT CTGGAGCTCT TCCCCTGAAC 60
AGCTCTACAA GCCTGGAAAA AAATAATGTG CTATTTβGTG AAAGATACTT AGAAAAATTT 120
TATGGCCTTG AβATAAACAA ACTTCCAGTG ACAAAAATGA AATATAGTGG AAACTTAATG 180
AAGeAAAAAA TCCAAβAAAT GCAGCACTTC TTGGGTCTGA AAGTGACCGG GCAACTGGAC 240
ACATCTACCC TGGAGATGAT GCACGCACCT CGATGTGGAG TCCCCGATGT CCATCATTTC 300
AGGGAAATGC CAGGGGGGCC CGTATGGAGG AAACATTATA TCACCTACAG AATCAATAAT 360
TACACACCTG ACATGAACCG TGAGGATGTT GACTACGCAA TCCGGAAAGC TTTCCAAGTA 420
TGGAGTAATG TTACCCCCTT GAAATTCAGC AAGATTAACA CAGGCATGGC TGACATTTTG 480
GTGGTTTTTβ CCCGTGGAGC TCATGGAGAC TTCCATGCTT TTGATGGCAA AGGTGGAATC 540
CTAGCCCATG CTTTTGGACC TGGATCTGGC ATTGGAGGGG ATGCACATTT CGATGAGGAC 600
GAATTCTGGA CTACACATTC AGGAGGCACA AACTTβTTCC TCACTGCTGT TCACGAGATT 660
GGCCATTCCT TAGGTCTTGG CCATTCTAGT GATCCAAAGG CCβTAATβTT CCCCACCTAC 720
AAATATGTTG ACATCAACAC ATTTCGCCTC TCTGCTGATβ ACATACGTGG CATTCAGTCC 780
CTGTATGβAG ACCCAAAAGA GAACCAACGC TTβCCAAATC CTGACAATTC AGAACCAGCT 840
CTCTGTGACC CCAATTTGAG TTTTGATGCT GTCACTACCG TGGGAAATAA GATCTTTTTC 900
TTCAAAGACA GGTTCTTCTG GCTGAAGGTT TCTGAGAGAC CAAAGACCAG TGTTAATTTA 960
ATTTCTTCCT TATGGCCAAC CTTGCCATCT GGCATTGAAG CTGCTTATGA AATTGAAβCC 1020
AGAAATCAAG TTTTTCTTTT TAAAGATGAC AAATACTGGT TAATTAGCAA TTTAAGACCA 1080
GAGCCAAATT ATCCCAAGAG CATACATTCT TTTGGTTTTC CTAACTTTGT GAAAAAAATT 1140
GATGCAGCTG TTTTTAACCC ACGTTTTTAT AGGACCTACT TCTTTGTAGA TAACCAGTAT 1200
TGGAGGTATG ATGAAAGGAG ACAGATGATβ GACCCTGGTT ATCCCAAACT GATTACCAAG 1260
AACTTCCAAG GAATCGGGCC TAAAATTGAT βCACTCTTCT ACTCTAAAAA CAAATACTAC 1320
TATTTCTTCC AAGGATCTAA CCAATTTGAA TATGACTTCC TACTCCAACG TATCACCAAA 1380
ACACTGAAAA GCAATAβCTG GTTTGGTTGT TGA 1413
Seq ID NO: C81 DNA Sequence
Nucleic Acid Accession ft: Eos sequence
Coding sequence: 1..1413
1 11 21 31 41 51
1 1 J 1 | 1 | 1 I 1 1 1 ATGAAGTTTC TTCTAATACT GCTCCTGCAG GCCACTGCTT CTGGAGCTCT TCCCCTGAAC 60
AGCTCTACAA GCCTGGAAAA AAATAATGTG CTATTTGGTG AAAGATACTT AGAAAAATTT 120
TATGGCCTTG AGATAAACAA ACTTCCAGTG ACAAAAATGA AATATAGTGG AAACTTAATG 180
AAGGAAAAAA TCCAAGAAAT GCAGCACTTC TTGGGTCTGA AAGTGACCGG GCAACTGGAC 240
ACATCTACCC TGGAGATGAT GCACGCACCT CGATGTGGAG TCCCCGATGT CCATCATTTC 300
AGGGAAATGC CAGGGGGGCC CGTATGGAGG AAACATTATA TCACCTACAG AATCAATAAT 360
TACACACCTG ACATGAACCG TGAGGATGTT GACTACGCAA TCCGGAAAGC TTTCCAAGTA 420
TGGAGTAATG TTACCCCCTT GAAATTCAGC AAGATTAACA CAGGCATGGC TGACATTTTG 480
GTGGTTTTTG CCCGTGβAGC TCATGGAGAC TTCCATGCTT TTGATGGCAA AGGTGGAATC 540
CTAGCCCATG CTTTTCβACC TGGATCTGGC ATTGGAGGGG ATGCACATTT CGATGAGGAC 600
GAATTCTGGA CTACACATTC AGGAGGCACA AACTTGTTCC TCACTGCTGT TCACGCCATT 660
GGCCATTCCT TAGGTCTTGG CCATTCTAGT GATCCAAAGG CCGTAATGTT CCCCACCTAC 720
AAATATGTTG ACATCAACAC ATTTCGCCTC TCTGCTGATG ACATACGTGG CATTCAGTCC 780
CTGTATGGAG ACCCAAAAGA GAACCAACGC TTGCCAAATC CTGACAATTC AGAACCAGCT 840
CTCTGTGACC CCAATTTGAG TTTTGATGCT GTCACTACCG TGGGAAATAA GATCTTTTTC 900
TTCAAAGACA GGTTCTTCTG GCTGAAGGTT TCTGAGAβAC CAAAGACCAG TGTTAATTTA 960
ATTTCTTCCT TATGGCCAAC CTTGCCATCT GGCATTGAAG CTGCTTATGA AATTGAAGCC 1020
AGAAATCAAG TTTTTCTTTT TAAAGATGAC AAATACTGGT TAATTAGCAA TTTAAGACCA 1080
GAGCCAAATT ATCCCAAGAG CATACATTCT TTTGGTTTTC CTAACTTTGT GAAAAAAATT 1140 GATGCAGCTG TTTTTAACCC ACGTTTTTAT AGGACCTACT TCTTTGTAGA TAACCAGTAT 1200
TGGAGGTATG ATGAAAGGAG ACAGATGATG GACCCTGGTT ATCCCAAACT GATTACCAAG 1260
AACTTCCAAG GAATCGGGCC TAAAATTGAT GCAGTCTTCT ACTCTAAAAA CAAATACTAC 1320
TATTTCTTCC AAGGATCTAA CCAATTTGAA TATGACTTCC TACTCCAACG TATCACCAAA 1380
ACACTβAAAA GCAATAGCTG GTTTGGTTGT TGA 1413
Seq ID NO: C82 DNA Sequence
Nucleic Acid Accession #: NM_006952.
Coding sequence: 11..793
1 11 21 31 41 51 1 1 [ 1 1 1 | 1 1 1 | 1 AATCCCGACA ATGGCGAAAG ACAACTCAAC TGTTCGTTGC TTCCAGGGCC TβCTGATTTT 60
TGGAAATGTG ATTATTGGTT GTTGCGGCAT TGCCCTGACT GCGGAGTGCA TCTTCTTTGT 120
ATCTGACCAA CACAβCCTCT ACCCACTGCT TβAAGCCACC GACAACGATG ACATCTATββ 180
GGCTGCCTGG ATCGGCATAT TTβTβGGCAT CTGCCTCTTC TGCCTGTCTG TTCTAGGCAT 240
TGTAGGCATC ATGAAβTCCA GCAGGAAAAT TCTTCTGGCG TATTTCATTC TGATGTTTAT 300
AGTATATGCC TTTβAAGTGG CATCTTGTAT CACAGCAGCA ACACAACGAG ACTTTTTCAC 360
ACCCAACCTC TTCCTGAAGC AGATGCTAGA GAGGTACCAA AACAACAGCC CTCCAAACAA 420
TGATGACCAG TGβAAAAACA ATGGAGTCAC CAAAACCTGG GACAGGCTCA TGCTCCAββA 480
CAATTGCTGT GGCGTAAATG GTCCATCAGA CTGGCAAAAA TACACATCTG CCTTCCGGAC 540
TGAβAATAAT GATGCTGACT ATCCCTGGCC TCGTCAATGC TGTGTTATGA ACAATCTTAA 600
AGAACCTCTC AACCTGGAGG CTTGTAAACT AGGCGTGCCT GGTTTTTATC ACAATCAGGG 660
CTGCTATGAA CTGATCTCTG GTCCAATGAA CCGACACGCC TGGGβGGTTG CCTGGTTTGG 720
ATTTGCCATT CTCTGCTGGA CTTTTTGGGT TCTCCTG6GT ACCATGTTCT ACTGGAGCAG 780
AATTGAATAT TAAGAA 796
Seq ID NO: C83 DNA Sequence Nucleic Acid Accession #: NM_001793.2 Coding sequence: 71..2560
11 21 31 51
AAAGGGGCAA GAβCTGAGCG GAACACCGGC CCGCCGTCGC GGCAGCTGCT TCACCCCTCT 60
CTCTGCAGCC ATGGGGCTCC CTCGTGGACC TCTCGCGTCT CTCCTCCTTC TCCAGGTTTG 120
CTGGCTGCAG TGCGCGGCCT CCGAGCCGTβ CCGGGCβGTC TTCAGGGAGβ CTGAAGTGAC 180
CTTGGAGGCG GβAβGCGCGG AGCAGGAGCC CGβCCAββCβ CTGGβGAAAG TATTCATGGG 240
CTGCCCTGGG CAAGAGCCAG CTCTCTTTAG CACTGATAAT GATGACTTCA CTGTGCGGAA 300
TGGCGAGACA GTCCAGGAAA GAAGGTCACT GAAGGAAAGG AATCCATTGA AGATCTTCCC 360
ATCCAAACGT ATCTTACGAA GACACAAGAβ AβATTGGGTG GTTGCTCCAA TATCTGTCCC 420
TGAAAATGGC AAGβGTCCCT TCCCCCAGAG ACTGAATCAG CTCAAGTCTA ATAAAGATAG 480
AGACACCAAG ATTTTCTACA GCATCACGGG GCCGGGGGCA GACAβCCCCC CTGAGGGTGT 540
CTTCGCTGTA GAGAAGGAGA CAGGCTGGTT GTTGTTGAAT AAβCCACTGG ACCGGGAGGA 600
GATTGCCAAG TATGAβCTCT TTGGCCACGC TGTβTCAGAG AATGGTGCCT CAGTGGAGGA 660
CCCCATGAAC ATCTCCATCA TCGTGACCGA CCAGAATGAC CACAAGCCCA AGTTTACCCA 720 ββACACCTTC CβAGGGAGTG TCTTAGAGGG AGTCCTACCA GGTACTTCTG TGATGCAGGT 780
GACAGCCACG GATGAGGATG ATGCCATCTA CACCTACAAT GGGGTGGTTG CTTACTCCAT 840
CCATAGCCAA GAACCAAAGG ACCCACACGA CCTCATGTTC ACCATTCACC GGAGCACAGG 900
CACCATCAGC βTCATCTCCA GTGGCCTGGA CCββGAAAAA GTCCCTGAβT ACACACTGAC 960
CATCCAGβCC ACAβACATGG ATGGβGACGG CTCCACCACC ACGGCA6TGG CAGTAGTGGA 1020
GATCCTTGAT GCCAATGACA ATGCTCCCAT GTTTGACCCC CAGAAGTACG AGGCCCATGT 1080
GCCTGAGAAT GCAGTGGGCC ATGAGGTGCA GAGGCTGACG GTCACTGATC TGGACGCCCC 1140
CAACTCACCA GCCTGGCGTG CCACCTACCT TATCATGGGC GGTGACGACG GGGACCATTT 1200
TACCATCACC ACCCACCCTG AGAGCAACCA GGGCATCCTG ACAACCAGGA AGβGTTTGGA 1260
TTTTGAGGCC AAAAACCAGC ACACCCTGTA CGTTGAAGTG ACCAACGAGG CCCCTTTTGT 1320
GCTGAAGCTC CCAACCTCCA CAGCCACCAT AGTβGTCCAC GTGGAGGATG TGAATGAββC 1380
ACCTGTGTTT GTCCCACCCT CCAAAGTCGT TGAGGTCCAG GAGβGCATCC CCACTGGGGA 1440
GCCTβTGTGT GTCTACACTG CAGAAGACCC TGACAAGGAG AATCAAAAGA TCAGCTACCG 1500
CATCCTGAGA GACCCAGCAG GGTβGCTAGC CATGGACCCA GACAGTGGGC AGβTCACACC 1560
TGTGGGCACC CTCGACCGTG AGGATGAGCA GTTTGTGAGG AACAACATCT ATGAAGTCAT 1620
GGTCTTGGCC ATGβACAATG GAAGCCCTCC CACCACTGGC ACGGGAACCC TTCTGCTAAC 1680
ACTGATTGAT GTCAATGACC ATGGCCCAGT CCCTGAGCCC CGTCAGATCA CCATCTGCAA 1740
CCAAAGCCCT GTGCβCCAGG TGCTGAACAT CACGGACAAG GACCTGTCTC CCCACACCTC 1800
CCCTTTCCAG GCCCAGCTCA CAGATGACTC AGACATCTAC TGGACGGCAG AGGTCAACGA 1860
GGAAGGTβAC ACAGTGGTCT TGTCCGTGAA GAAGTTCCTG AAGCAGGATA CATATGACGT 1920
GCACCTTTCT CTGTCTGACC ATGGCAACAA AGAGCAGCTG ACGGTGATCA GGGCCACTGT 1980
GTGCGACTGC CATGGCCATG TCGAAACCTG CCCTGGACCC TGGAAGGGAG GTTTCATCCT 2040
CCCTGTGCTG GGGGCTGTCC TGGCTCTGCT GTTCCTCCTβ CTGGTGCTGC TTTTGTTGGT 2100
GAGAAAGAAG CGGAAGATCA AGGAGCCCCT CCTACTCCCA GAAGATGACA CCCGTGACAA 2160
CGTCTTCTAC TATG6CGAAG AGGGGGGTGG CGAAGAGβAC CAGGACTATG ACATCACCCA 2220
GCTCCACCGA GGTCTGGAGG CCAGGCCGβA GGTGGTTCTC CGCAATβACG TGCCACCAAC 2280
CATCATCCCG ACACCCATGT ACCGTCCTCG GCCAGCCAAC CCAGATGAAA TCGGCAACTT 2340
TATAATTGAG AACCTGAAGG CGGCTAACAC AGACCCCACA GCCCCGCCCT ACGACACCCT 2400
CTTGGTGTTC GACTATGAGG GCAGCGGCTC CGACGCCβCβ TCCCTGAGCT CCCTCACCTC 2460
CTCCGCCTCC GACCAAGACC AAGATTACGA TTATCTGAAC GAβTβGGGCA GCCGCTTCAA 2520
GAAβCTGGCA GACATGTACG GTGGCGGGGA GGACGACTAG GCGβCCTGCC TGCAGGGCTβ 2580
GGGACCAAAC GTCAGGCCAC AGAGCATCTC CAAGGGGTCT CAGTTCCCCC TTCACCTGAG 2640
GACTTCGGAG CTTGTCAGGA AGTGGCCGTA GCAACTTGGC GGAGACAGGC TATGAGTCTG 2700
ACGTTAGAGT GGTTGCTTCC TTAGCCTTTC AGGATGGAGG AATGTGGGCA GTTTGACTTC 2760
AGCACTGAAA ACCTCTCCAC CTGGGCCAGG GTTGCCTCAG AGGCCAAGTT TCCAGAAGCC 2820
TCTTACCTGC CGTAAAATGC TCAACCCTGT GTCCTGGGCC TGGGCCTGCT GTGACTGACC 2880
TACAGTGGAC TTTCTCTCTG GAATGGAACC TTCTTAGGCC TCCTGGTGCA ACTTAATTTT 2940
TTTTTTTAAT GCTATCTTCA AAACGTTAGA GAAAGTTCTT CAAAAGTGCA GCCCAGAGCT 3000
GCTGGGCCCA CTβeccβTcc TGCATTTCTG GTTTCCAGAC CCCAATGCCT CCCATTCGGA 3060 TGGATCTCTG CGTTTTTATA CTGAGTGTGC CTAGGTTGCC CCTTATTTTT TATTTTCCCT 3120 GTTGCGTTGC TATAGATGAA GGGTGAGGAC AATCGTGTAT ATGTACTAGA ACTTTTTTAT 3180 TAAAGAAACT TTTCCCAGAA AAAAA 3205
Seq ID NO: C84 DNA Sequence
Nucleic Acid Accession ft: NM_005629.1
Coding sequence: 639..2546
1 11 21 31 41 51
I I I I I I
TAGTCGGAGC GAGGTGGCGA βTCβCTGAGC CCGCCGCCGC CCCGAGAGCG GCTGCAGCCC 60
CCGCCGCCGG GAAGGAGAGβ GCGAGGCGCG CCCGAGCCGC CGCCGCCGCC GCCACCβCCβ 120
CCGCCGCCAC CACCGCCACC GGAGTCGCGG GCCAGCCGGG CAGCCTCCGC GGGCCCCGGC 180
CGGGGCGGGG GGCCCGGGCC ACAGGCCCCT GCTCCGGCCG TCGTTTGCAG ACCGCGGβCG 240
CCGATGTCGC CCGCGCCCCG TTAGGATGAG TCTCGGGTCG GGCGAGGAGC CGCCGCAGCC 300
GCCGCCGCCC GAGCCGCGGG CAGGAβCCTC GGGAGCCGCC GCCGCCGCCG CCGCCGCCGG 360
GCCGGGCCCC GACGCCGCCC GCGCGCCCCC GGGCCCCCGA CACACATGAG ATTCTTCAGG 420
CTCACTTTCA AGTGCTTCGT GGACTGCTTC TGACTGCGCC GCCCGCGCCC CGGACCCCGC 480
CGTCCGCCCG CCGCCCCGTC CCCCGGCCCG GCCGCCCCCC GGCCCCCGGC CGGCCCGCGC 540
CCTCGGGGCC CTCCCCGGTG CCGCCGGTGC CCCCCGCGTG ACCGCCGCCC CCCGTGAGGC 600
GCCGCGACCC CGGCCCGGCC GTGCGGCCCG CCGGGGCCAT GGCGAAGAAG AGCGCCGAGA 660
ACGGCATCTA TAGCGTβTCC GGCGACGAGA AGAAGGGCCC CCTCATCGCG CCCGGGCCCG 720
ACG6GGCCCC βGCCAAGβGC GACGGCCCCG TGGGCCTGGG GACACCCGGC GGCCGCCTGG 780
CCGTGCCGCC GCGCGAGACC TGGACGCGCC AGATGGACTT CATCATGTCG TGCGTGGGCT 840
TCGCCGTGGG CTTGGGCAAC GTGTGGCGCT TCCCCTACCT GTGCTACAAG AACGGCGGAG 900
GTGTGTTCCT TATTCCCTAC GTCCTGATCG CCCTGGTTββ AGGAATCCCC ATTTTCTTCT 960
TAGAGATCTC GCTGGGCCAG TTCATGAAGG CCGGCAGCAT CAATGTCTGG AACATCTGTC 1020
CCCTGTTCAA AGGCCTGGGC TACGCCTCCA TGGTGATCGT CTTCTACTGC AACACCTACT 1080
ACATCATGGT GCTGGCCTGβ GGCTTCTATT ACCTGGTCAA GTCCTTTACC ACCACGCTGC 1140
CCTGGGCCAC ATGTGGCCAG ACCTGGAACA CTCCCGACTG CGTGGAGATC TTCCGCCATG 1200
AAGACTGTGC CAATGCCAGC CTGGCCAACC TCACCTGTGA CCAGCTTGCT GACCGCCGGT 1260
CCCCTGTCAT CGAGTTCTGG GAGAACAAAG TCTTGAGβCT GTCTGGGGGA CTGGAGGTβC 1320
GAGGGGCCCT CAACTGGGAG GTGACCCTTT GTCTGCTGGC CTGCTGGGTG CTGGTCTACT 1380
TCTGTβTCTG GAAGGGGGTC AAATCCACGG GAAAβATCGT GTACTTCACT GCTACATTCC 1440
CCTACGTGGT CCTGGTCGTG CTGCTGGTGC CTGGAGTGCT GCTGCCTGGC GCCCTG6ATG 1500
GCATCATTTA CTATCTCAAG CCTGACTGGT CAAAGCTGGG GTCCCCTCAG GTGTGGATAG 1560
ATGCGβGGAC CCAGATTTTC TTTTCTTACG CCATTGβCCT GGGGGCCCTC ACAGCCCTGG 1620
GCAGCTACAA CCGCTTCAAC AACAACTGCT ACAAGβACβC CATCATCCTG GCTCTCATCA 1680
ACAGTGGβAC CAGCTTCTTT GCTGGCTTCG TGGTCTTCTC CATCCTGGGC TTCATGGCTG 1740
CAGAGCAGGG CGTGCACATC TCCAAGGTGG CAGAGTCAGG GCCGGGCCTG GCCTTCATCG 1800
CCTACCCGCG GGCTGTCACG CTGATGCCAG TGGCCCCACT CTGGGCTGCC CTGTTCTTCT 1860
TCATGCTGTT GCTGCTTGGT CTCGACAGCC AGTTTβTAGG TGTGGAGGGC TTCATCACCG 1920
GCCTCCTCβA CCTCCTCCCβ GCCTCCTACT ACTTCCGTTT CCAAAGGGAG ATCTCTGTβG 1980
CCCTCTGTTG TGCCCTCTβC TTTGTCATCG ATCTCTCCAT GGTGACTGAT GGCGGGATβT 2040
ACGTCTTCCA GCTGTTTGAC TACTACTCGβ CCAGCGGCAC CACCCTGCTC TGGCAGGCCT 2100
TTTG6GAGTG CGTGGTGGTG GCCTGβGTβT ACGGAGCTGA CCGCTTCATG GACGACATTG 2160
CCTGTATGAT CβGGTACCGA CCTTGCCCCT GGATGAAATG GTGCTβGTCC TTCTTCACCC 2220
CGCTGGTCTG CATGGGCATC TTCATCTTCA ACGTTGTGTA CTACGAGCCG CTGGTCTACA 2280
ACAACACCTA CGTβTACCCG TGGTGGGGTG AGGCCATGGG CTGGGCCTTC GCCCTGTCCT 2340
CCATGCTGTG CGTGCCGCTG CACCTCCTGG GCTGCCTCCT CAGGGCCAAG GGCACCATGG 2400
CTGAβCGCTG GCAGCACCTG ACCCAGCCCA TCTGGGβCCT CCACCACTTG GAGTACCGAG 2460
CTCAGGACGC AGATGTCAGG GGCCTGACCA CCCTGACCCC AGTGTCCGAG AβCAGCAAGG 2520
TCGTCGTGGT GGAGAGTGTC ATGTGACAAC TCAGCTCACA TCACCAGCTC ACCTCTGGTA 2580
GCCATA6CAG CCCCTGCTTC AGCCCCACCG CACCCCTCCA GGGGGCCTGC CTTTGCCTGA 2640
CACTTTTGGG GTCTGCCTGβ GGGAGGAGGG GAGAAAGCAC CATGAGTGCT CACTAAAACA 2700
ACTTTTTCCA TTTTTAATAA AACGCCAAAA ATATCACAAC CCACCAAAAA TAGATGCCTC 2760
TCCCCCTCCA GCCCTAGCCβ AGCTGGTCCT AGGCCCCGCC TAGTGCCCCA CCCCCACCCA 2820
CAGTGCTGCA CTCCTCCTGC CCCTGCCACG CCCACCCCCT GCCCACCTCT CCAGGCTCTG 2880
CTCTGCAGCA CACCCGTGGG TGACCCCTCA CCCCAGAAβC AGCAGTGGCA GCTTGGGAAA 2940
TGTGAGGAAG GGAAGGAGGG AGAGACGGGA GGGAGGAGAG AGAGGAGAAG GGAGGCAGGG 3000
GAGGGGCAGC AGAACCAAβG CAAATATTTC AGCTGGGCTA TACCCCTCTC CCCATCCCTG 3060
TTATAGAAGC TTAβAGAGCC AGCCAGCAAT GGAACCTTCT GGTTCCTGCG CCAATCGCCA 3120
CCAGTATCAA TTGTGTGAGC TTGGGTGCGA GTGCACGCGT GCGTGAGTAC GGAGAGTATA 3180
TATAGATCTC TATCTCTTAG CAAAGGTGAA TGCCAGATGT AAATGGCGCC TCTGGGCAAA 3240
GGAGGCTTGT ATTTTGCACA TTTTATAAAA ACTTβAGAGA ATGAGATTTC TGCTTGTATA 3300
TTTCTAAAAA GAGGAAGGAG CCCAAACCAT CCTCTCCTTA CCACTCCCAT CCCTGTGAGC 3360
CCTACCTTAC CCCTCTGCCC CTAGCCAAGG AGTGTGAATT TATAGATCTA ACTTTCATAG 3420
GCAAAACAAA AGCTTCGAβC TGTTβCβTGT GTGAGTCTGT TGTGTGGATG TGCGTGTGTG 3480
GTCCCCAGCC CCAGACTGGA TTGGAAAAGT GCATGGTGGG GGCCTCGGGG CTGTCCCCAC 3540
GCTGTCCCTT TGCCACAAGT CTGTGGGGCA AGAGGCTGCA ATATTCCGTC CTGGGTGTCT 3600 βGGCTGCTAA CCTGβCCTGC TCAGGCTTCC CACCCTGTGC GGGGCACACC CCCAGGAAGG 3660
GACCCTGGAC ACGGCTCCCA CGTCCAGGCT TAAGGTββAT GCACTTCCCG CACCTCCAGT 3720
CTTCTGTGTA GCAGCTTTAA CCCACGTTTG TCTGTCACGT CCAGTCCCGA GACGGCTGAG 3780
TGACCCCAAG AAAGGCTTCC CCGACACCCA GACAβAGGCT GCAGGGCTGG GGCTGGGTGA 3840
GGGTGGCGGG CCTGCGGGGA CATTCTACTG TGCTAAAAAG CCACTGCAGA CATAGCAATA 3900
AAAACATCTC ATTTTCC 3917
Seq ID NO: C8S DNA Sequence
Nucleic Acid Accession ff: NM_006516.1
Coding sequence: 180..1658
1 11 21 31 41 51
I I I I I I
TAGTCGCGβG TCCCCGAGTG AGCACGCCAC GGAGCAGGAG ACCAAACGAC GGGGGTCGGA 60 GTCAGAGTCG CAGTGGGAGT CCCCGGACCG GAGCACGAGC CTGAGCGGGA GAGCGCCGCT 120
CGCACβCCCG TCGCCACCCG CGTACCCGGC GCAGCCAGAG CCACCAGCGC AGCGCTGCCA 180
TGGAGCCCAG CAGCAAGAAG CTGACGGGTC GCCTCATGCT GGCTGTGGGA GGAGCAGTGC 240
TTGβCTCCCT GCAGTTTGGC TACAACACTG GAβTCATCAA TGCCCCCCAG AAGGTGATCG 300
AGGAGTTCTA CAACCAGACA TGGGTCCACC GCTATGβGGA GAGCATCCTC CCCACCACGC 360
TCACCACGCT CTGGTCCCTC TCAGTGGCCA TCTTTTCTGT TGGβGGCATG ATTGGCTCCT 420
TCTCTGTGGG CCTTTTCGTT AACCGCTTTG GCCGGCGGAA TTCAATGCTG ATGATGAACC 480
TGCTGGCCTT CGTGTCCGCC GTGCTCATGG GCTTCTCGAA ACTGGGCAAG TCCTTTGAGA 540
TGCTGATCCT GGGCCGCTTC ATCATCGGTβ TGTACT6CGG CCTGACCACA GβCTTCGTGC 600
CCATGTATβT GGGTGAAGTG TCACCCACAβ CCTTTCGTββ GGCCCTGGGC ACCCTGCACC 660
AGCTGGGCAT CGTCGTCGGC ATCCTCATCC CCCAGGTβTT CGGCCTGGAC TCCATCATGG 720
GCAACAAGGA CCTGTGGCCC CTGCTGCTGA βCATCATCTT CATCCCGGCC CTGCTGCAGT 780
GCATCGTGCT GCCCTTCTGC CCCGAGAGTC CCCGCTTCCT GCTCATCAAC CGCAACGAGG 840
AGAACCGGGC CAAGAGTGTG CTAAAGAAGC TGCGCGGGAC AGCTGACGTG ACCCATGACC 900
TGCAGGAGAT GAAGGAAGAG AGTCGGCAGA TGATGCGGGA GAAGAAGGTC ACCATCCTGG 960
AGCTGTTCCG CTCCCCCGCC TACCGCCAGC CCATCCTCAT CGCTGTGGTG CTGCAGCTGT 1020
CCCAGCAGCT βTCTGGCATC AACGCTβTCT TCTATTACTC CACβAGCATC TTCGAGAAGG 1080
CGGGGβTGCA GCAGCCTGTG TATβCCACCA TTGGCTCCGβ TATCGTCAAC ACGGCCTTCA 1140
CTGTCGT6TC GCTGTTTGTG βTGGAGCGAG CAGGCCGGCG GACCCTGCAC CTCATAGGCC 1200
TCCCTGGCAT GβCGGGTTGT GCCATACTCA TGACCATCGC GCTAGCACTG CTGGAGCAGC 1260
TACCCTGGAT GTCCTATCTG AGCATCGTGG CCATCTTTGG CTTTGTGGCC TTCTTTGAAG 1320
TGGGTCCTGG CCCCATCCCA TββTTCATCβ TGGCTGAACT CTTCAGCCAG GβTCCACGTC 1380
CAGCTGCCAT TGCCGTTGCA CGCTTCTCCA ACTGGACCTC AAATTTCATT GTGGGCATGT 1440 βCTTCCAGTA TGTGGAGCAA CTGTGTGGTC CCTACGTCTT CATCATCTTC AGTGTGCTCC 1500
TGGTTCTGTT CTTCATCTTC ACCTACTTCA AAGTTCCTGA GACTAAAGGC CGGACCTTCG 1560
ATGAGATCGC TTCCGGCTTC CGGCAGGGGG GAβCCACCCA AAGTGATAAG ACACCCGAGG 1620
AGCTGTTCCA TCCCCTGGβG GCTGATTCCC AAGTβTβAβT CGCCCCAGAT CACCAGCCCG 1680
GCCTGCTCCC AGCAGCCCTA AGGATCTCTC AGGAGCACAβ βCAGCTGGAT GAGACTTCCA 1740
AACCTGACAG ATGTCAGCCG AGCCGGGCCT GGGGCTCCTT TCTCCAGCCA GCAATGATGT 1800
CCAGAAGAAT ATTCAGGACT TAACGGCTCC AGGATTTTAA CAAAAGCAAG ACTGTTGCTC 1860
AAATCTATTC AGACAAGCAA CAGGTTTTAT AATTTTTTTA TTACTGATTT TGTTATTTTT 1920
ATATCAGCCT GAGTCTCCTG TGCCCACATC CCAGGCTTCA CCCTGAATGG TTCCATGCCT 1980
GAGGGTGGAG ACTAAGCCCT GTCGAGACAC TTGCCTTCTT CACCCAGCTA ATCTGTAGGβ 2040
CTGGACCTAT GTCCTAAGGA CACACTAATC GAACTATGAA CTACAAAGCT TCTATCCCAβ 2100
GAGGTGGCTA TGGCCACCCG TTCTGCTGGC CTGGATCTCC CCACTCTAGG GGTCAGGCTC 2160
CATTAGGATT TGCCCCTTCC CATCTCTTCC TACCCAACCA CTCAAATTAA TGTTTCTTTA 2220
CCTGAGACCA GTTGGGAGCA CTGGAGTGCA GGGAGGAGAG GGGAAGGGCC AGTCTGGGCT 2280
GCCGGβTTCT AGTCTCCTTT GCACTGAGGG CCACACTATT ACCATGAGAA GAGGGCCTGT 2340
GβGAGCCTGC AAACTCACTG CTCAAGAAGA CATGGAGACT CCTGCCCTGT TGTGTATAGA 2400
TGCAAGATAT TTATATATAT TTTTGGTTGT CAATATTAAA TACAGACACT AAGTTATAGT 2460
ATATCTGGAC AAGCCAACTT GTAAATACAC CACCTCACTC CTGTTACTTA CCTAAACAβA 2520
TATAAATGGC TGGTTTTTAG AAACATGGTT TTGAAATGCT TGTGGATTGA GGGTAGGAββ 2580
TTTGGATGGG AGTGAGACAG AAGTAAGTGG GGTTGCAACC ACTGCAACGG CTTAGACTTC 2640
GACTCAGGAT CCAGTCCCTT ACACGTACCT CTCATCAGTG TCCTCTTGCT CAAAAATCTG 2700
TTTGATCCCT GTTACCCAGA GAATATATAC ATTCTTTATC TTGACATTCA AββCATTTCT 2760
ATCACATATT TGATAGTTGG TGTTCAAAAA AACACTAGTT TTGTGCCAGC CβTGATGCTC 2820
AGβCTTGAAA TCGCATTATT TTGAATGTGA AGGGAA 2856
Seq ID NO: C86 DNA Sequence
Nucleic Acid Accession ft : XM_035292 .2
Coding sequence: 53 . .1576
1 11 21 31 41 51
1 1 ] 1 | 1 | 1 | 1 | 1 GCTCGCTGGG CCGCGGCTCC CGGGTGTCCC AGGCCCGGCC GGTGCGCAGA GCATGGCGGG 60
TGCGGGCCCG AAGCGGCGCG CGCTAGCGGC GCCGGCGGCC GAGGAGAAGG AAGAGGCGCβ 120
GGAGAAGATG CTGGCCGCCA AGAGCGCGGA CGGCTCGGCG CCGGCAGGCG AGGGCGAGGG 180
CGTGACCCTG CAGCGGAACA TCACGCTGCT CAACGGCGTG GCCATCATCG TGGGGACCAT 240
TATCGGCTCG GGCATCTTCG T6ACGCCCAC GGGCGTGCTC AAGGAGGCAG GCTCGCCGGG 300
GCTGGCGCTG GTGGTGTGGG CCGCGTGCGG CGTCTTCTCC ATCGTGGGCG CGCTCTGCTA 360
CGCGβAGCTC GβCACCACCA TCTCCAAATC GGGCGCCGAC TACGCCTACA TGCTGGAGGT 420
CTACGGCTCG CTGCCCGCCT TCCTCAAGCT CTGGATCGAG CTGCTCATCA TCCGGCCTTC 480
ATCGCAGTAC ATCGTGGCCC TGGTCTTCGC CACCTACCTG CTCAAGCCGC TCTTCCCCAC 540
CTGCCCGGTG CCCGAGGAGG CAGCCAAGCT CGTGGCCTGC CTCTGCGTGC TGCTGCTCAC 600
GGCCGTGAAC TGCTACAGCG TGAAβGCCβC CACcceeβTc CAGGATGCCT TTGCCGCCGC 660
CAAGCTCCTG GCCCTGGCCC TGATCATCCT GCTGGGCTTC GTCCAGATCG GAAAGGGTGA 720
TGTGTCCAAT CTAGATCCCA ACTTCTCATT TGAAGβCACC AAACTGGATG TGGGGAACAT 780
TGTβCTGGCA TTATACAGCG GCCTCTTTGC CTATGβAGβA TGGAATTACT TGAATTTCGT 840
CACAGAGGAA ATGATCAACC CCTACAGAAA CCTGCCCCTG GCCATCATCA TCTCCCTGCC 900
CATCGTGACG CTGGTGTACG TGCTGACCAA CCTGGCCTAC TTCACCACCC TGTCCACCGA 960
GCAGATGCTG TCGTCCGAGG CCGTGGCCGT GGACTTCGGG AACTATCACC TGGGCGTCAT 1020
GTCCTGGATC ATCCCCβTCT TCGTGGGCCT GTCCTGCTTC GGCTCCGTCA ATGGGTCCCT 1080
GTTCACATCC TCCAGGCTCT TCTTCGTGGG GTCCCGGGAA GGCCACCTGC CCTCCATCCT 1140
CTCCATGATC CACCCACAGC TCCTCACCCC CGTGCCGTCC CTCGTGTTCA CGTGTGTGAT 1200
GACGCTGCTC TACGCCTTCT CCAAGGACAT CTTCTCCGTC ATCAACTTCT TCAGCTTCTT 1260
CAACTGGCTC TGCGTGGCCC TGGCCATCAT CGGCATGATC TGGCTGCGCC ACAGAAAGCC 1320
TCAGCTTGAG CGGCCCATCA AGGTGAACCT GGCCCTGCCT GTGTTCTTCA TCCTβGCCTG 1380
CCTCTTCCTG ATCGCCGTCT CCTTCTGGAA GACACCCGTG GAβTGTGGCA TCGGCTTCAC 1440
CATCATCCTC AGCGGGCTGC CCGTCTACTT CTTCGGGGTC TGGTGGAAAA ACAAGCCCAA 1500
GTGGCTCCTC CAGGGCATCT TCTCCACGAC CGTCCTGTGT CAGAAGCTCA TGCAGGTGGT 1560
CCCCCAGGAG ACATAGCCAG GAGGCCGAGT GGCTGCCGβA GGAGCATGC 1609
Seq ID NO: C87 DNA Sequence
Nucleic Acid Accession ff: NM_005268.1 Coding sequence: 168..989
11 21 31 41 51
I I I I I
TAAAAAGCAA AAGAATTCGC GGCCGCGTCG ACACGGGCTT CCCCGAAAAC CTTCCCCGCT 60 TCTGGATATG AAATTCAAGC TGCTTGCTGA GTCCTATTGC CGGCTGCTGG GAGCCAGGAG 120 AGCCCTGAGG AGTAGTCACT CAGTAGCAGC TGACGCGTGG GTCCACCATG AACTGGAGTA 180 TCTTTGAGGG ACTCCTGAGT GGββTCAACA AGTACTCCAC AGCCTTTGGG CGCATCTGGC 240 TGTCTCTGGT CTTCATCTTC CGCGTGCTGG TβTACCTβGT GACGGCCGAG CGTGTGTGGA 300 GTGATGACCA GAAGGACTTC GACTCCAATA CTCGCCAβCC CGGCTβCTCC AACGTCTGCT 360 TTGATGAGTT CTTCCCTGTβ TCCCATGTGC GCCTCTGGGC CCTGCAGCTT ATCCTGGTGA 420 CATGCCCCTC ACTGCTCβTβ GTCATGCACG TGGCCTACCG GGAGGTTCAG GAGAAGAGGC 480 ACCGAGAAGC CCATCGGGAG AACAGTGGGC GCCTCTACCT GAACCCCGβC AAGAAGCGGG 540 GTGGGCTCTG GTGGACATAT GTCTGCAGCC TAGTGTTCAA GGCβAβCGTG GACATCGCCT 600 TTCTCTATGT GTTCCACTCA TTCTACCCCA AATATATCCT CCCTCCTGTG GTCAAGTGCC 660 ACGCAGATCC ATGTCCCAAT ATAGTGGACT GCTTCATCTC CAAGCCCTCA GAGAAGAACA 720 TTTTCACCCT CTTCATGGTG GCCACAGCTG CCATCTGCAT CCTβCTCAAC CTCGTGGAGC 780 TCATCTACCT GGTGAGCAAG AGATGCCACG AGTGCCTGGC AGCAAGGAAA GCTCAAGCCA 840 TGTGCACAGG TCATCACCCC CACGGTACCA CCTCTTCCTG CAAACAAGAC GACCTCCTTT 900 CGGGTGACCT CATCTTTCTG GGCTCAGACA GTCATCCTCC TCTCTTACCA GACCGCCCCC 960 GAGACCATGT 6AAGAAAACC ATCTTGTGAG GGGCTGCCTG GACTGβTCTG GCAGGTTGGG 1020 CCTGGATGGG GAGGCTCTAG CATCTCTCAT AGGTGCAACC TGAGAGTGGG GGAGCTAAGC 1080 CATGAGGTAG GGGCAGGCAA GAGAGAGGAT TCAGACGCTC TGGGAGCCAG TTCCTAGTCC 1140 TCAACTCCAG CCACCTGCCC CAGCTCGACG GCACTβeecc AGTTCCCCCT CTGCTCTGCA 1200 GCTCGGTTTC CTTTTCTAGA ATGGAAATAG TβAβGβCCAA TCC 1243
Seq ID NO: C88 DNA Sequence Nucleic Acid Accession ft: NM.005130 Coding sequence : 98..802
60
Figure imgf001251_0001
120
GCTCTCCTTC CTCCTACTGG CTGCTCAGGT βCTCCTββTG GAGGβGAAAA AAAAAGTGAA 180
GAATGGACTT CACAGCAAAG TGGTCTCAGA ACAAAAGGAC ACTCTGGGCA ACACCCAβAT 240
TAAGCAGAAA AGCAGGCCCG GGAACAAAGG CAAβTTTβTC ACCAAAGACC AAβCCAACTG 300
CAGATGGGCT GCTACTGAβC AGGAGGAGGG CATCTCTCTC AAGGTTGAGT GCACTCAATT 360
GβACCATGAA TTTTCCTCTG TCTTTGCTGG CAATCCAACC TCATGCCTAA AGCTCAAGGA 420
TβAGAGAGTC TATTGGAAAC AAGTTGCCCG βAATCTGCGC TCACAGAAAG ACATCTGTAG 480
ATATTCCAAG ACAGCTGTGA AAACCAGAGT GTGCAGAAAG βATTTTCCAG AATCCAGTCT 540
TAAGCTAGTC AGCTCCACTG TATTTGGGAA CACAAAGCCC AβGAAGGAGA AAACAGAGAT 600 βTCCCCCAGC GAGCACATCA AGGGCAAAGA GACCACCCCC TCTAGCCTAG CAβTβACCCA 660
GACCATGGCC ACCAAAGCTC CCGAGTGTGT GGAGGACCCA GATATGGCAA ACCAGAβGAA 720
GACTGCCCTG GAGTTCTGTG GAGAGACTTG GAGCTCTCTC TGCACATTCT TCCTCAGCAT 780
AGTGCAGGAC ACGTCATGCT AATGAGGTCA AAAGAGAACG GGTTCCTTTA AGAGATGTCA 840
TGTCGTAAGT CCCTCTGTAT ACTTTAAAGC TCTCTACAGT CCCCCCAAAA TATGAACTTT 900
TGTGCTTAGT GAGTGCAACG AAATATTTAA ACAAGTTTTG TATTTTTTGC TTTTGTGTTT 960
TGGAATTTGC CTTATTTTTC TTGGATGCGA TGTTCAGAGG CTGTTTCCTG CAGCATβTAT 1020
TTCCATGGCC CACACAGCTA TGTGTTTGAG CAGCGAAGAG TCTTTGAGCT GAATGAβCCA 1080
GAGTGATAAT TTCAGTGCAA CGAACTTTCT GCTGAATTAA TGGTAATAAA ACTCTGβGTG 1140
TTTTTCAAAA AAAAAAAAAA AAA 1163
Seq ID NO: C89 DNA Sequence Nucleic Acid Accession ft : BC022542 Coding sequence : 274 . - 927
1 11 21 31 41 51 1 1 1 1 | 1 | 1 | 1 | 1 ACTTGGTCCC AGCCGATAAA TCTGGGGCAG CGCGCGGTAG GAGCTGCGGG CGGCCAGGCC 60
CCTTCCTGCG TCCGCACCTG GCCCCGCGCG CCCCTCTCGG GCGTCCGGCT TCCGGCGTCC 120
TGGCGGCTCG GGTGGCGGCG GTTCGGGCGG CCGCCTGGCT GCTCCTCGGG GCGGCGACGG 180
GβCTCACGCG CGGGCCCGCC ACGGCCTTCA CCGCCβCβCG CTCTβACGCC GGCATAAGGG 240
CCATGTGTTC TGAAATTATT TTGAGGCAAG AAGTTTTGAA AβATGGTTTC CACAGAGACC 300
TTTTAATCAA AGTGAAGTTT GGβGAAAGCA TTGAGGACTT GCACACGTGC CGTCTCTTAA 360
TTAAACAGGA CATTCCTGCA GGACTTTATG TGGATCCGTA TGAGTTGGCT TCATTACGAβ 420
AGAGAAACAT AACAGAGGCA GTGATGGTTT CAGAAAATTT TGATATAGAG GCCCCTAACT 480
ATTTGTCCAA GGAGTCTGAA GTTCTCATTT ATGCCAGACG AGATTCACAG TGCATTGACT 540
GTTTTCAAGC CTTTTTGCCT 6TGCACTGCC GCTATCATCG GCCGCACAGT GAAGATGGAG 600
AAGCCTCGAT TGTGGTCAAT AACCCAGATT TGTTGATGTT TTCTGACCAA GA6TTCCCGA 660
TTTTGAAATG CTGGGCTCAC TCAGAAGTGG CAGCCCCTTG TGCTTTGGAT AATGAGGATA 720
TATGCCAATG GAACAAGATG AAGTATAAAT CAGTATATAA GAATGTGATT CTACAAGTTC 780
CAGTGGGACT GACTGTACAT ACCTCTCTAG TATGTTCTGT GACTCTGCTC ATTACAATCC 840
TGTGCTCTAC ATTGATCCTT GTAGCAGTTT TCAAATATGG CCATTTTTCC CTATAAGTTT 900
TATGTAGTTA AATGCTTCCT AGAAACCTAA ATAAGATCTA TTAATTTCTG ACGAβAGGTG 960
TTCTTCTAGA ATTAATTACT TTTATCTTTT GTCTTCATTT GTββCCAAAA TTATGTTTAC 1020
TAGAGGAAAT TTGGGATCAT TCTCAGCTAA TTCCAAAATG TAGTGCTCTA TTβCATββAT 1080
CCTTGGTAAT CCTCAAGCAT CAGATGCCAT AAGGGGAAAC TTAATTCTβC TAAATTAATG 1140
TTTATTTTGT GAGAAGTGAC TTTATCTTCA TTTGGGGTAG AAAAATTATT TCTTTATGTA 1200
GTAGAGACAA ATTATTCTCA TTTTGCAAGT ACTTTCAATT TAAGCTACAA ATTGAGAAAA 1260
CCGTTATAAA TAAGAATAAA ATAβGCCAGG CACAGTGβCT CACACCTGTA ATCCCAGCAC 1320
TTTGGGAGGC CGAGGTGGGC GGATCACCAG AGGTCAAGAG TTTGAGACCA GCTTGGTGAA 1380
ACCCTGTCTC TACTAAAAAT ACAAAAGTTA GCTGGGGCTG GTGGTGGGCA TCTGTAGTCC 1440
CAGCTAATTG GAAGGGTGAG GCGGGAGGAT CGCTTGAACC TGGGAGGCGG AGGTTCCAGA 1500 GAGCCAAGAT CGCACCACTG CACTACAGCC TGGGCGACAG AACGAGACCC TGTCTCCAAA 1560
GGAAAAACAA AAAAGAAGAA TAAAATAATT TGGATGAAAA TCATGTTTAT TTAAATAβTA 1620
ATGTCATGAG ACTATTAAAG ATGTGCCAGA GTTTCAATβA AAATCATTAA AGTAGGACAG 1680
CTAAGAAATT AATATTAATA TAAAAATTAT TGATAATCTT AAATTATTGA TTATTCCTTA 1740
ACGCACTCCA TTCTCCTTTT ACATTTTATC ATGTTTCTTT TGAATATATG AATTGGCAAA 1800
GGACTTGATβ AAACTGAGTA CTAAGATTTG GTACAGAGTA TGTCAGGAAG ACAACTCAGA 1860
TTGCCATTTT AAATAAAGTT GTACATGAAC AAAAAAAAAA AAAAAA 1906
Seq ID NO C90 DNA Sequence Nucleic Acid Accession # NM_004994 Coding sequence 20 2143
11 21 31
AGACACCTCT GCCCTCACCA TGAGCCTCTG GCAGCCCCTG GTCCTGGTGC TCCTGGTGCT 60
GGGCTGCTGC TTTGCTGCCC CCAGACAGCβ CCAβTCCACC CTTGTGCTCT TCCCTGGAGA 120
CCTGAGAACC AATCTCACCG ACAGGCAGCT GGCAGAGGAA TACCTGTACC GCTATGGTTA 180
CACTCGGGTG GCAGAGATGC GTGGAGAGTC GAAATCTCTG GGGCCTGCGC TGCTGCTTCT 240
CCAGAAGCAA CTGTCCCTGC CCGAGACCGG TGAGCTGGAT AGCGCCACGC TGAAGGCCAT 300 βCGAACCCCA CGGTGCGGGG TCCCAGACCT GβGCAGATTC CAAACCTTTG ACGGCGAGCT 360
CAAGTGGCAC CACCACAACA TCACCTATTG GATCCAAAAC TACTC6GAAG ACTTGCCGCG 420
GGCGGTGATT GACGACGCCT TTGCCCGCGC CTTCGCACTG TGGAGCGCGG TGACGCCGCT 480
CACCTTCACT CGCGTGTACA GCCGGGACGC AGACATCGTC ATCCAGTTTG GTGTCGCGGA 540
GCACGGAGAC GGGTATCCCT TCGACGGGAA GGACGGGCTC CTGGCACACG CCTTTCCTCC 600
TGGCCCCGGC ATTCAGββAG ACGCCCATTT CGACGATGAC GAGTTGTGGT CCCTGGGCAA 660
GGGCGTCGTG GTTCCAACTC GGTTTGGAAA CGCAβATGGC GCGGCCTGCC ACTTCCCCTT 720
CATCTTCGAG GGCCGCTCCT ACTCTGCCTG CACCACCGAC GGTCβCTCCG ACGGCTTGCC 780
CTGGTGCAGT ACCACGGCCA ACTACGACAC CGACGACCGG TTTGGCTTCT GCCCCAGCGA 840
GAGACTCTAC ACCCGGGACG GCAATGCTGA TGGGAAACCC TGCCAGTTTC CATTCATCTT 900
CCAAGGCCAA TCCTACTCCG CCTGCACCAC GGACGGTCGC TCCGACGGCT ACCGCTGGTG 960
CGCCACCACC GCCAACTACG ACCGGGACAA GCTCTTCGGC TTCTGCCCGA CCCGAGCTGA 1020
CTCGACGGTG ATGGGGGGCA ACTCGGCGGG GβAGCTGTGC GTCTTCCCCT TCACTTTCCT 1080
GGGTAAGGAG TACTCGACCT GTACCAGCGA GGGCCGCGGA GATGGGCGCC TCTGGTGCGC 1140
TACCACCTCG AACTTTGACA GCGACAAGAA GTGGGGCTTC TGCCCGGACC AAGGATACAG 1200
TTTGTTCCTC GTGGCβGCGC ATGAGTTCGG CCACGCGCTG GGCTTAGATC ATTCCTCAGT 1260
GCCGGAGGCG CTCATGTACC CTATGTACCG CTTCACTGAG GGGCCCCCCT TGCATAAGGA 1320
CGACGTGAAT GGCATCCGGC ACCTCTATGG TCCTCGCCCT GAACCTGAGC CACGβCCTCC 1380
AACCACCACC ACACCβCACC CCACGGCTCC CCCGACGGTC TGCCCCACCG βACCCCCCAC 1440
TGTCCACCCC TCAβAβCβCC CCACAGCTGG CCCCACAGGT CCCCCCTCAG CTGGCCCCAC 1500
AGGTCCCCCC ACTGCTGβCC CTTCTACCGC CACTACTGTG CCTTTGAGTC CGGTGGACGA 1560
TGCCTGCAAC GTGAACATCT TCGACGCCAT CGCGGAGATT GGGAACCAGC TGTATTTGTT 1620
CAAGGATGGG AAGTACTGβC GATTCTCTGA GGβCACGGGG AGCCGβCCGC AGGβCCCCTT 1680
CCTTATCGCC βACAAβTβGC CCGCGCTGCC CCGCAAGCTG GACTCGβTCT TTGAGGAGCC 1740
GCTCTCCAAG AAGCTTTTCT TCTTCTCTGG GCGCCAGGTβ TGGGTGTACA CAGGCGCGTC 1800
GGTGCTGββC CCGAGGCGTC TGGACAAGCT GGGCCTGGGA GCCGACGTGG CCCAGGTGAC 1860
CGGGGCCCTC CGGAGTGGCA GGGGGAAGAT GCTGCTGTTC AGCGGGCGGC GCCTCTGGAG 1920
GTTCGACGTG AAGGCGCAGA TGGTGGATCC CCGGAGCGCC AGCGAGGTGG ACCGGATGTT 1980
CCCCGGGGTG CCTTTGGACA CGCACGACGT CTTCCAGTAC CGAGAGAAAG CCTATTTCTG 2040
CCAGGACCGC TTCTACTGGC GCGTGAGTTC CCGGAGTGAG TTGAACCAGG TGGACCAAGT 2100
GGGCTACGTG ACCTATGACA TCCTGCAGTβ CCCTGAGGAC TAGGβCTCCC GTCCTGCTTT 2160
GCAGTGCCAT GTAAATCCCC ACTGGβACCA ACCCTGGΘ3A AGGAGCCAGT TTGCCGGATA 2220
CAAACTGGTA TTCTGTTCTG GAGGAAAGGG AGGAGTGGAG GTGGGCTGGG CCCTCTCTTC 2280
TCACCTTTCT TTTTTGTTGG AGTGTTTCTA ATAAACTTGG ATTCTCTAAC CTTT 2334
Seq ID NO C91 Sequence
Nucleic Acid Accession ft NM_000213
Coding sequence 188 5656
11 21 31 51
GCGCTGCCCG CCTCGTCCCC ACCCCCCAAC CCCCCGCGCC CGCCCTCGGA CAGTCCCTGC 60
TCGCCCGCGC GCTGCAGCCC CATCTCCTAG CGGCAGCCCA GGCGCGβAGG GAGCGAGTCC 120
GCCCCGAGGT AGGTCCAGGA CGGGCGCACA GCAGCAGCCG AGGCTGGCCG GGAGAGGGAG 180
GAAGAGGATG GCAGGGCCAC GCCCCAGCCC ATGGGCCAGG CTGCTCCTGG CAGCCTTGAT 240
CAGCGTCAGC CTCTCTGGGA CCTTGGCAAA CCGCTGCAAG AAGGCCCCAG TGAAGAGCTG 300
CACGGAGTGT GTCCGTGTGG ATAAGGACTG CGCCTACTGC ACAGACβAβA TGTTCAGGGA 360
CCGGCGCTGC AACACCCAGG CGGAβCTGCT GGCCGCGGGC TGCCAGCGGG AGAGCATCGT 420
GGTCATGGAG AGCAGCTTCC AAATCACAGA GGAGACCCAG ATTGACACCA CCCTGCGGCG 480
CAGCCAGATG TCCCCCCAAG GCCTGCGGGT CCGTCTGCGβ CCCGGTGAGG AβC∞CATTT 540
TGAGCTGGAG GTGTTTGAGC CACTGGAGAG CCCCGTGGAC CTGTACATCC TCATGGACTT 600
CTCCAACTCC ATGTCCGATG ATCTGGACAA CCTCAAGAAG ATGGGβCAGA ACCTGGCTCG 660
GGTCCTGAGC CAGCTCACCA GCGACTACAC TATTGGATTT GGCAAGTTTG TGGACAAAGT 720
CAGCGTCCCG CAGACGβACA TGAGGCCTGA GAAGCTGAAβ GAGCCCTGGC CCAACAGTGA 780
CCCCCCCTTC TCCTTCAAGA ACGTCATCAG CCTGACAGAA GATGTGGATG AGTTCCGGAA 840
TAAACTGCAG GGAGAGCGGA TCTCAGGCAA CCTGGATGCT CCTGAβGGCβ GCTTCGATGC 900
CATCCTGCAG ACAGCTGTGT GCACGAGGGA CATTGGCTββ CGCCCGGACA GCACCCACCT 960
GCTGGTCTTC TCCACCGAGT CAGCCTTCCA CTATGAGGCT GATGGCGCCA ACGTGCTGGC 1020
TGGCATCATG AGCCGCAACG ATGAACGGTG CCACCTGGAC ACCACGGGCA CCTACACCCA 1080
GTACAGGACA CAGGACTACC CGTCGGTGCC CACCCTGGTG CGCCTGCTCG CCAAGCACAA 1140
CATCATCCCC ATCTTTGCTG TCACCAACTA CTCCTATAGC TACTACGAGA AGCTTCACAC 1200
CTATTTCCCT GTCTCCTCAC TGGGGGTGCT GCAGGAβGAC TCGTCCAACA TCGTGGAGCT 1260
GCTGβAGGAβ GCCTTCAATC GGATCCGCTC CAACCTGGAC ATCCGGGCCC TAGACAGCCC 1320
CCGAGGCCTT CGGACAGAGG TCACCTCCAA GATGTTCCAG AAGACGAβGA CTGGGTCCTT 1380
TCACATCCGG CGGGGGGAAG TGGGTATATA CCAGGTGCAG CTGCGGGCCC TTGAGCACGT 1440 βGATGGGACG CACGTGTGCC AGCTGCCGGA GGACCAGAAG GGCAACATCC ATCTGAAACC 1500
TTCCTTCTCC GACGGCCTCA AGATGGACGC GGβCATCATC TGTGATGTGT GCACCTGCGA 1560
GCTGCAAAAA GAGGTGCGGT CAGCTCGCTC CAGCTTCAAC GGAGACTTCG TGTGCGGACA 1620
GTGTCTGTGC AGCGAGGGCT GGAGTGGCCA GACCTGCAAC TGCTCCACCG GCTCTCTGAG 1680
TGACATTCAG CCCTGCCTGC GGGAGGGCGA GGACAAGCCG TGCTCCGβCC GTGGββAGTG 1740
CCAGTGCGββ CACTGTGTGT βCTACGGCGA AGβCCGCTAC GAGGGTCAGT TCTGCGAβTA 1800
TGACAACTTC CAGTGTCCCC GCACTTCCGG GTTCCTGTGC AATGACCGAG GACGCTGCTC 1860
CATGGGCCAG TGTGTGTGTG AGCCTGGTTG GACAGβCCCA AGCTGTGACT GTCCCCTCAG 1920
CAATGCCACC TGCATCGACA GCAATGGGGG CATCTGTAAT GGACGTGGCC ACTGTGAGTG 1980
TGGCCGCTGC CACTGCCACC AGCAGTCGCT CTACACGGAC ACCATCTGCG AGATCAACTA 2040
CTCGGCGATC CACCCGGGCC TCTGCGAGGA CCTACGCTCC TGCGTGCAGT GCCAββCβTG 2100
GββCACCβGC GAGAAGAAGG GGCGCACGTG TGAGGAATGC AACTTCAAGG TCAAβATβGT 2160
G6ACGAGCTT AAGAGAGCCG AGGAGGTGGT GGTGCGCTGC TCCTTCCGGG ACGAGGATGA 2220
CGACTGCACC TACAGCTACA CCATGGAAGG TGACGGCGCC CCTCβGCCCA ACAGCACTGT 2280
CCTGGTGCAC AAGAAGAAGG ACTGCCCTCC GG6CTCCTTC TβGTGGCTCA TCCCCCTGCT 2340
CCTCCTCCTG CTGCCGCTCC TGGCCCTGCT ACTGCTGCTA TGCTGGAAGT ACTGTβCCTG 2400
CTGCAAGGCC TGCCTGGCAC TTCTCCCGTG CTβCAACCβA βGTCACATGG TGGGCTTTAA 2460
GGAAGACCAC TACATGCTGC GG6AGAACCT GATGGCCTCT GACCACTTGG ACACGCCCAT 2520 βCTβCGCAGC GGGAACCTCA AGββCCGTGA CGTβGTCCGC TGGAAGGTCA CCAACAACAT 2580
GCAGCGGCCT GGCTTTGCCA CTCATGCCGC CAGCATCAAC CCCACAGAβC TGGTGCCCTA 2640
CGGGCTGTCC TTGCGCCTGG CCCGCCTTTG CACCGAGAAC CTGCTβAAGC CTGACACTCG 2700
GGAGTGCGCC CAGCTGCGCC AGGAGGTGGA GGAGAACCTG AACGAGGTCT ACAGβCAGAT 2760
CTCCGGTGTA CACAAGCTCC AGCAGACCAA GTTCCGGCAG CAGCCCAATG CCGGGAAAAA 2820 βCAACACCAC ACCATTGTGG ACACAGTβCT GATGGCGCCC CGCTCGGCCA AGCCGGCCCT 2880
GCTGAAβCTT ACAGAGAAGC AGGTGGAACA GAGGGCCTTC CACGACCTCA AGGTGGCCCC 2940
CGGCTACTAC ACCCTCACTG CAGACCAGGA CGCCCGGGGC ATCGTβGAGT TCCAGGAGGG 3000
CGTGGAGCTG GTGGACGTAC GGGTGCCCCT CTTTATCCGG CCTGAGGATG ACGACGAGAA 3060
GCAGCTGCTG GTGGAGβCCA TCGACGTβCC CβCAGGCACT GCCACCCTCG GCCGCCβCCT 3120 ββTAAACATC ACCATCATCA AβGAGCAAGC CAGAGACGTG GTGTCCTTTG AGCAGCCTGA 3180
GTTCTCGGTC AGCCGCGGGβ ACCAGGTGGC CCGCATCCCT GTCATCCGGC GTGTCCTGGA 3240
CGGCβGGAAG TCCCAGGTCT CCTACCGCAC ACAGGATGGC ACCGCGCAGG GCAACCGGGA 3300
CTACATCCCC GTGGAGGGTG AGCTGCTGTT CCAGCCTGGG GAβGCCTGGA AAGAGCTGCA 3360
GβTβAAGCTC CTGGAGCTGC AAGAAGTTGA CTCCCTCCTG CGGGGCCGCC AGGTCCGCCG 3420
TTTCCACGTC CAGCTCAGCA ACCCTAAGTT TGGGGCCCAC CTGGGCCAGC CCCACTCCAC 3480
CAGCATCATC ATCAGGGACC CAGATGAACT GGACCGGAGC TTCACGAGTC AGATGTTGTC 3540
ATCACAGCCA CCCCCTCACβ GCGACCTGGG CGCCCCGCAG AACCCCAATG CTAAGGCCGC 3600
TGGGTCCAGG AAGATCCATT TCAACTGGCT GCCCCCTTCT GGCAAGCCAA TGGGGTACAG 3660
GGTAAAGTAC TGGATTCAGG GCGACTCCGA ATCCGAAGCC CACCTGCTCG ACAGCAAGGT 3720
GCCCTCAGTG GAGCTCACCA ACCTGTACCC GTATTGCGAC TATGAGATGA AGGTGTGCGC 3780
CTACGGGGCT CAGGGCGAGG GACCCTACAG CTCCCTGGTG TCCTGCCGCA CCCACCAGGA 3840
AGTGCCCAGC GAGCCAGGGC GTCTGGCCTT CAATGTCGTC TCCTCCACGβ TGACCCAGCT 3900
GAGCTGGβCT GAGCCGGCTG AGACCAACGG TGAGATCACA GCCTACGAGG TCTGCTATGG 3960
CCTGGTCAAC βATGACAACC GACCTATTGG GCCCATGAAG AAAGTGCTGG TTGACAACCC 4020
TAAGAACCGG ATGCTGCTTA TTGAGAACCT TCGGGAGTCC CAGCCCTACC GCTACACGGT 4080
GAAGGCGCGC AACGGββCCβ βCTGGGGGCC TGAGCGββAG GCCATCATCA ACCTGβCCAC 4140
CCAβCCCAAG AGGCCCATGT CCATCCCCAT CATCCCTGAC ATCCCTATCG TGGACGCCCA 4200
GAGCGGGβAG GACTACGACA GCTTCCTTAT GTACAGCGAT GACGTTCTAC GCTCTCCATC 4260
GGGCAGCCAG AGGCCCAGCG TCTCCGATGA CACTGGCTGC GGCTGGAAGT TCGAGCCCCT 4320
GCTGGGGGAG GAGCTGGACC TGCGGCGCGT CACGTGGCGG CTGCCCCCGG AGCTCATCCC 4380
GCGCCTGTCG GCCAGCAGCG GGCGCTCCTC CGACGCCGAG GCCCCCACGG CCCCCCGGAC 4440
GACGGCGGCG CGGGCGGGAA GGGCGGCAGC CGTGCCCCGC AGTGCGACAC CCGGGCCCCC 4500
CGGAGAGCAC CTGGTβAATG GCCGGATGGA CTTTGCCTTC CCGGGCAGCA CCAACTCCCT 4560
GCACAGGATG ACCACGACCA GTGCTGCTGC CTATGβCACC CACCTGAGCC CACACGTGCC 4620
CCACCGCGTG CTAAGCACAT CCTCCACCCT CACACGGGAC TACAACTCAC TGACCCGCTC 4680
AGAACACTCA CACTCGACCA CACTGCCCAG GGACTACTCC ACCCTCACCT CCGTCTCCTC 4740
CCACGACTCT CGCCTGACTG CTGGTGTGCC CGACACGCCC ACCCGCCTGG TGTTCTCTGC 4800
CCTGGGGCCC ACATCTCTCA GAGTGAGCTG GCAGGAGCCG CGGTGCGAGC GGCCGCTGCA 4860
GGGCTACAGT GTGGAGTACC AGCTβCTGAA CGGCGGTGAG CTGCATCGGC TCAACATCCC 4920
CAACCCTGCC CAGACCTCGG TGGTGGTGGA AGACCTCCTG CCCAACCACT CCTACGTGTT 4980
CCGCGTGCGG GCCCAGAGCC AGGAAGGCTG GGGCCGAβAβ CβTGAGGGTG TCATCACCAT 5040
TGAATCCCAG GTGCACCCGC AGAGCCCACT GTGTCCCCTG CCAGGCTCCG CCTTCACTTT 5100
GAGCACTCCC AGTGCCCCAG GCCCGCTGβT GTTCACTGCC CTGAGCCCAG ACTCGCTGCA 5160
GCTGAGCTGβ GAGCGGCCAC GGAGGCCCAA TGGGGATATC GTCGGCTACC TGGTGACCTG 5220 TGAGATGGCC CAAGGAGGAG GGCCAGCCAC CGCATTCCCG GTGGATGGAG ACAGCCCCGA 5280 GAGCCGGCTG ACCGTGCCGG GCCTCAGCGA GAACGTGCCC TACAAGTTCA AGGTGCAGGC 5340 CAGGACCACT GAGGGCTTCG GGCCAGAβCG CGAGGGCATC ATCACCATAG AβTCCCACGA 5400 TGGAGGACCC TTCCCGCAGC TGGGCAGCCG TβCCGβGCTC TTCCAGCACC CGCTGCAAAG 5460 CGAβTACAGC AGCATCACCA CCACCCACAC CAGCGCCACC GAGCCCTTCC TAGTGβATGG 5520 βCTCACCCTG GGGGCCCAGC ACCTGGAGGC AGGCβGCTCC CTCACCCGGC ATGTGACCCA 5580 GGAGTTTGTG AGCCGGACAC TGACCACCAG CGGAACCCTT AGCACCCACA TGGACCAACA 5640 GTTCTTCCAA ACTTGACCGC ACCCTGCCCC ACCCCCGCCA TGTCCCACTA GGCGTCCTCC 5700 CGACTCCTCT CCCGGAGCCT CCTCAβCTAC TCCATCCTTG CACCCCTGGG GGCCCAGCCC 5760 ACCCGCATGC ACAGAGCAGG GGCTAGGTGT CTCCTGGGAG GCAT6AAGGG GGCAAGGTCC 5820 GTCCTCTGTG GGCCCAAACC TATTTGTAAC CAAAGAGCTG GGAGCACCAC AAGGACCCAG 5880 CCTTTGTTCT GCACTTAATA AATGGTTTTG CTACTGCTAA AAAAAAAAAA AAAAAAAAAA 5940 AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAA 5994
Seq ID NO : C92 DNA Sequence Nucleic Acid Accession ft : NM_023915 Coding sequence : 250 . . 1326
1 11 21 31 41 51
I I I I I I
GGCACGAGGG TTTCGTTTTC ATGCTTTACC AGAAAATCCA CTTCCCTGCC GACCTTAGTT 60 TCAAAGCTTA TTCTTAATTA GAGACAAGAA ACCTGTTTCA ACTTGAAGAC ACCGTATGAG 120
GTGAATGGAC AGCCAGCCAC CACAATGAAA GAAATCAAAC CAGGAATAAC CTATGCTGAA 180
CCCACGCCTC AATCGTCCCC AAGTGTTTCC TGACACGCAT CTTTGCTTAC AGTGCATCAC 240
AACTGAAGAA TCGGGTTCAA CTTGACGCTT GCAAAATTAC CAAATAACCA GCTGCACGβC 300
CAAGAGAGTC ACAATTCAGG CAACAGGAGC GACGGGCCAG GAAAGAACAC CACCCTTCAC 360
AATGAATTTG ACACAATTGT CTTGCCGGTG CTTTATCTCA TTATATTTGT GGCAAGCATC 420
TTβCTGAATβ GTTTAGCAGT GTGGATCTTC TTCCACATTA GGAATAAAAC CAGCTTCATA 480
TTCTATCTCA AAAACATAGT GGTTGCAGAC CTCATAATGA CGCTCACATT TCCATTTCGA 540
ATAGTCCATG ATGCAGGATT TGGACCTTGG TACTTCAAGT TTATTCTCTG CAGATACACT 600
TCAGTTTTGT TTTATGCAAA CATβTATACT TCCATCGTGT TCCTTGGGCT GATAAGGATT 660
GATCGCTATC TGAAGβTGGT CAAβCCATTT GGGGACTCTC GGATGTACAG CATAACCTTC 720
ACGAAGGTTT TATCTGTTTβ TGTTTGGGTG ATCATGGCTG TTTTGTCTTT GCCAAACATC 780
ATCCTGACAA ATGGTCAβCC AACAGAGGAC AATATCCATG ACTGCTCAAA ACTTAAAAGT 840
CCTTTGGGGG TCAAATββCA TACGGCAGTC ACCTATGTGA ACAGCTGCTT GTTTβTGGCC 900
GTGCTGGTGA TTCTGATCGG ATGTTACATA GCCATATCCA GGTACATCCA CAAATCCAGC 960
AGGCAATTCA TAAGTCAGTC AAβCCβAAAβ CGAAAACATA ACCAGAGCAT CAGGGTTGTT 1020
GTGGCTGTGT TTTTTACCTG CTTTCTACCA TATCACTTGT GCAGAATTCC TTTTACTTTT 1080
AβTCACTTAβ ACAGGCTTTT AGATGAATCT GCACAAAAAA TCCTATATTA CTGCAAAGAA 1140
ATTACACTTT TCTTGTCTGC GTGTAATGTT TGCCTGβATC CAATAATTTA CTTTTTCATG 1200
TGTAGGTCAT TTTCAAGAAG GCTGTTCAAA AAATCAAATA TCAGAACCAG GAβTGAAAGC 1260
ATCAGATCAC TGCAAAGTGT GAGAAGATCG GAAGTTCGCA TATATTATGA TTACACTGAT 1320
GTGTAGGCCT TTTATTGTTT GTTGGAATCG ATATGTACAA AGTGTAAATA AATGTTTCTT 1380
TTCATTATCC TTAAAAAAAA AA 1402
Seq ID NO: C93 DNA Sequence
Nucleic Acid Accession ff: NM.020789.
Coding sequence: 208..3699
11 21 31 51
GGCACGAGGG TGGAGCCGAG CGGTGCGGAG CAGATCTGGT GGTTCTCCβG AGAGCAGCTT 60
CCTTGGGTGT TACATGAGCC AAGCCCTCAC TGTACAGAAG AGTGAGAGCT GAAACCTGTT 120
CCCTGAGCTG ATCAGAAGGA CATCCCTTGG CCCCTCCATC TGGGCTCCTG TGGATAGGAG 180
GββCTGGGTG AGCAββCCAG CTGGGCTATG GTGTββTβCC TCGGCCTGGC CGTCCTCAGC 240
CTGGTCATCA GCCAGGGβGC TGACGGTCGA GGGAAGCCTβ AGGTGGTATC GGTGGTββGC 300
CGGβCTGAGG AGAGTGTGGT GCTGGGCTGT GACCTGCTGC CCCCGGCCGG CCGGCCCCCC 360
CTGCATGTCA TCGAβTGGCT GCGCTTTGGA TTCCTGCTTC CCATCTTCAT ccAGTTceec 420
CTCTACTCTC CCCGAATTGA CCCTGATTAC GTGGGACGAG TCCGGCTGCA GAAGGGGGCC 480
TCTCTCCAGA TTGAGββTCT CCGGGTGGAA GACCAGGGCT GβTACGAGTG CCGCGTGTTC 540
TTCCTGGACC AGCACATCCC TGAAGACGAT TTTGCTAACG GCTCCTGGGT GCATCTGACA 600
GTCAATTCAC CCCCTCAATT CCAGGAGACA CCTCCTGCTG TβTTGGAAGT GCAGGAACTG 660
GAGCCTGTGA CCCTGCGTTG TGTGGCCCGT GGCAGCCCCC TGCCTCATGT GACGTGβAAβ 720
CTCCGAGβAA AGGACCTTGG CCAGGGCCAG GGCCAGGTGC AAβTGCAGAA CGGGACGCTC 780
CGGATCCGCC GGGTAGAβCβ AGGCAGCTCT GGGGTCTACA CCTGCCAAGC CTCCAGCACT 840
GAGGβCAGCG CCACCCACGC CACCCAGCTβ CTAGTβCTAC GACCCCCAGT CATCGTGGTG 900
CCCCCCAAGA ACAGCACAGT CAATGCCTCC CAGβATβTTT CATTGGCCTG CCATGCTGAG 960
GCATACCCTG CTAACCTCAC CTACAGCTGG TTCCAGGACA ACATCAATGT CTTCCACATT 1020
AGCCGCCTGC AGCCCCGGGT GCAGATCCTG βTβGACGGGA GCCTGCGGCT GCTGGCCACC 1080
CAGCCTGATG ATGCCGβCTG CTACACCTGT GTGCCCAGCA ATGGCCTCCT GCATCCACCC 1140
TCAGCCTCTG CCTACCTCAC TGTGCTCTGC ATGCCGGGGG TGATCCGCTG CCCGGTTCGT 1200
GCCAACCCCC CACTGCTCTT TGTCAGCTGG ACCAAGGATG GAAAGGCCCT GCAGCTGGAC 1260
AAGTTCCCTG GCTGGTCCCA GGβCACAGAA GGCTCACTGA TCATCGCCCT GGGGAACGAG 1320
GATGCCCTGG GAGAATACTC CTβCACCCCC TACAACAGTC TTGGTACCGC CGGGCCCTCT 1380
CCTGTGACCC GCGTGCTGGT CAAGβCTCCC CCAGCTTTTA TAGAGCGGCC CAAGGAAGAA 1440
TATTTCCAAG AAGTAGGGCG GGAGCTGCTC ATCCCCTGCT CCGCCCAAGG GGACCCTCCT 1500
CCTGTTGTCT CTTGGACCAA GGTGGGCCGG GGGCTβCAAG GCCAβGCCCA GCTGGACAGC 1560
AACAGCAGCC TCATCCTGCG ACCATTGACC AAGGAββCCC ACGGGCACTG GGAATGCAGT 1620
GCCAGCAATG CTGTGβCCCC AGTGGCCACC TCCA∞AACG TCTACGTGCT GGGCACTAGC 1680
CCTCATGTTG TCACCAATGT GTCCGTGGTG GCTTTGCCCA AGGGTGCCAA TGTCTCCTGG 1740 βAGCCTGGCT TTGATGGTGG TTATCTGCAG AGATTCAGTG TCTGGTACAC CCCACTGGCC 1800
AAGCGTCCTG ACCGAATGCA CCATGACTGG GTGTCCTTGG CAGTGCCTGT GGGGGCTGCT 1860
CACCTCCTAG TGCCAGGGCT GCAGCCCCAC ACCCAGTACC AβTTCAGCGT GCTAGCTCAG 1920
AAGAAGCTGG GGAGTGGTCC CTTCAGCGAA ATCGTCTTGT CTGCTCCGGA AGGGCTTCCT 1980
ACCACGCCAG CTGCACCCGG GCTTCCCCCA ACAGAGATAC CGCCTCCCCT GTCCCCTCCG 2040
CGGGGTCTGG TGGCAGTGAG GACACCCCGG GGGGTACTCC TGCATTGββA TCCCCCAGAG 2100
CTGGTCCCTA AGAGACTGGA TGGCTACGTC TTGGAAGGCC GGCAAGGCTC CCAGGGCTGG 2160
GAβGTGCTGG ACCCGGCTGT GβCAGGCACA GAAACAGAGC TGCTGGTGCC AGGCCTCATC 2220
AAGβATGTTC TCTACGAGTT CCβCCTCGTG GCCTTCGCGG GCAGCTTCGT CAGCGACCCC 2280
AGCAACACGβ CCAACGTCTC CACTTCCGGT CTGGAGGTCT ACCCTTCGCG CACGCAGCTG 2340
CCGGGCCTCC TGCCTCAGCC CGTGCTGGCC GGCGTGGTβG GCGGAβTCTβ CTTTCTGGGA 2400
GTGGCCGTCC TTGTGAGCAT CCTGβCCGGC TGCCTCCTGA ACCGGCGCAG GGCTGCCCGC 2460
CGCCGCCβCA AGCGCCTCCG CCAAGATCCA CCTCTTATCT TCTCTCCGAC CGGGAAGTCA 2520
GCTGCACCCT CTGCTCTGGG CTCAGGCAGT CCTGACAGCG TGGCGAAGCT GAAGCTCCAG 2580
GGATCCCCAG TCCCCAGCCT GCGCCAGAGT CTGCTCTGGG GGGATCCTGC CGGAACTCCC 2640
AGCCCCCACC CGGATCCTCC ATCTAGCCGG GβACCCTTAC CTCTGGAGCC CATTTGCCGG 2700
GGCCCAGACG GGCGCTTTGT GATGβGGCCC ACTGTGGCGG CCCCCCAGGA AAGGTCAGGC 2760
CGGGAGCAGG CAGAACCTCG GACTCCAGCC CAGCGTCTGG CCCGGTCCTT TGACTGTAGC 2820
AGCAGCAGCC CCAGTGGGGC ACCCCAGCCC CTCTGCATTG AAGACATCAG CCCTGTβGCA 2880
CCCCCTCCAG CAGCCCCACC CAGTCCCTTG CCAGGTCCTG GACCCCTGCT CCAGTACCTG 2940
AGCCTGCCCT TCTTCCGAGA GATGAATGTG GATGGGGACT GGCCCCCGCT TGAGGAGCCC 3000
AGCCCTGCTG CACCCCCAGA TTACATGGAT ACCCGβCβCT GTCCCACCTC ATCTTTCCTT 3060
CGTTCTCCAG AAACCCCTCC TGTATCCCCC AGGβAATCAC TTCCTGGGGC TGTGβTAβGG 3120
GCTGGGGCCA CTGCAGAGCC CCCTTACACA GCCCTGGCTC ACTGGACACT GAGGGAGCGG 3180
CTGCTCCCAβ GCCTTCTCCC TGCTGCCCCT CGAGGCAGCC TCACCAGCCA GAGCAβCGGG 3240 CGAGβCAGCG CTTCGTTCCT GCGGCCCCCC TCCACAGCCC CCTCTGCAGβ AGGCAGCTAC 3300
CTCAGCCCTG CTCCAGGAGA CACCAGCAGC TGGGCCAGTG GCCCTGAGAG ATGGCCCCGA 3360
AGGGAGCATG TGGTGACAGT CAGCAAGAGG AGGAACACAT CTGTGGACGA GAACTATGAG 3420
TGGGACTCAG AATTCCCTGG GGACATGGAA TTGCTGGAGA CTTTGCACCT GGGCTTGGCC 3480
AGCTCCCGGC TCAGACCTGA AGCTβAGACA GAGCTAGGTG TGAAβACTCC AGAGGAGGGC 3540
TGCCTCCTCA ACACTGCCCA TGTTACTGGC CCTGAGGCCC GCTGTGCTGC CCTTCGGGAG 3600 βAATTCCTβG CCTTCCβCCG CCGCCGAGAT GCTACTAGGG CTCGGCTACC AGCCTATCGA 3660
CAGCCAGTCC CCCACCCCGA ACAGGCCACT CTGGTGTGAA CATCCCTAAT GTGAGGCTGT 3720
GAAAAGGCAT ATGGACCTGC AAAGGAGGCC GCCAACCAGA CAGACCTAGT TTCAAACGAG 3780
GGCACTGCCC CTGCCTGCCC CTTTGGTGCC CAGGCACAGA CCCTGATAGT GGGTTTGGGT 3840
CACCTTGGTA TGGAATGTAT GTGCTGACCC CCTAGGTGAG TCTGGGGATT GGAACAGGGA 3900
TCTTAGGTCT GCCTCTCTCT CTCTCTCTCT CTCTCTCTCT CTCTCTCTGT GTGTGTGTGT 3960
GTGTGTGAAG TTTTTTACAG GTGAATAAAC AAAGTTTGAA AGAAAAAAAA AAAAAAAAAA 4020
AAAA 4024
Seq ID NO: C94 DNA Sequence Nucleic Acid Accession ft: NM_006875 Coding sequence: 186..1190
11 21 31 41 51
I I I I I
GAATTCGGCA CGAGCGCβCG GCGAATCTCA ACGCTGCGCC GTCTGCGGGC GCTTCCGGGC 60 CACCAGTTTC TCTGCTTTCC ACCCTGβCGC CCCCCAGCCC TGGCTCCCCA GCTβCGCTGC 120 CCCGGGCGTC CACGCCCTGC GGGCTTAGCG GGTTCAGTGG GCTCAATCTG CGCAGCGCCA 180 CCTCCATGTT GACCAAGCCT CTACAGGGGC CTCCCGCGCC CCCCGGGACC CCCAC6CCGC 240 CGCCAGGAGG CAAGGATCGG GAAGCGTTCG AGGCCGAGTA TCGACTCGGC CCCCTCCTGβ 300 GTAAGβGGGG CTTTGβCACC GTCTTCGCAG GACACCGCCT CACAGATCGA CTCCAGGTGβ 360 CCATCAAAGT GATTCCCCGG AATCGTGTGC TGGGCTGGTC CCCCTTGTCA βACTCAGTCA 420 CATGCCCACT CGAAGTCGCA CTGCTATGGA AAGTβGGTβC AGCTGGTGGG CACCCTGGCG 480 TGATCCGCCT GCTTGACTGG TTTGAGACAC AGGAAGGCTT CATGCTGGTC CTCGAGCGGC 540 CTTTGCCCβC CCAGGATCTC TTTGACTATA TCACAGAβAA GGβCCCACTG GGTGAAββCC 600 CAAGCCGCTG CTTCTTTGGC CAAGTAGTGG CAGCCATCCA GCACTGCCAT TCCCGTGGAG 660 TTGTCCATCG TGACATCAAG GATGAGAACA TCCTGATAGA CCTACGCCGT GβCTGTGCCA 720 AACTCATTGA TTTTGGTTCT GGTGCCCTβC TTCATGATGA ACCCTACACT GACTTTGATG 780 GGACAAGGGT GTACAGCCCC CCAGAGTGGA TCTCTCGACA CCAGTACCAT GCACTCCCGG 840 CCACTGTCTG GTCACTGGGC ATCCTCCTCT ATGACATGGT CTGTGGGGAC ATTCCCTTTG 900 AGAGGGACCA GβAGATTCTG GAAGCTGAGC TCCACTTCCC AGCCCATCTC TCCCCAGACT 960 GCTGTGCCCT AATCCGCCGG TGCCTGGCCC CCAAACCTTC TTCCCGACCC TCACTGGAAG 1020 AGATCCTGCT GGACCCCTGG ATGCAAACAC CAGCCGAGGA TGTTACCCCT CAACCCCTCC 1080 AAAGGAGGCC CTGCCCCTTT GGCCTGGTCC TTGCTACCCT AAGCCTCGCC TGGCCTβGCC 1140 TββCCCCCAA TGGTCAGAAG AGCCATCCCA TGGCCATGTC ACAGGGATAG ATGGACATTT 1200 GTTGACTTGG TTTTACAGGT CATTACCAGT CATTAAAGTC CAGTATTACT AAGGTAAGGG 1260 ATTGAGGATC AGGGGTTAGA AGACATAAAC CAAGTTTGCC CAGTTCCCTT CCCAATCCTA 1320 CAAAGGAGCC TTCCTCCCAG AACCTGTβGT CCCT6ATTTT GGAGGGGGAA CTTCTTGCTT 1380 CTCATTTTGC TAAGGAAGTT TATTTTGGTG AAGTTGTTCC CATTTTGAGC CCCGGGACTC 1440 TTATTTTGAT GATGTGTCAC CCCACATTGG CACCTCCTAC TACCACCACA CAAACTTAGT 1500 TCATATGCTT TTACTTGGGC AAGGGTGCTT TCCTTCCAAT ACCCCAGTAG CTTTTATTTT 1560 AGTAAAGGGA CCCTTTCCCC TAGCCTAGGG TCCCATATTG GGTCAAGCTG CTTACCTGCC 1620 TCAGCCCAGG ATTTTTTATT TTGGGGGAGG TAATβCCCTG TTGTTACCCC AAGGCTTCTT 1680
TTTTTTTTTG GGTGAGGGGA CCCTACTTTG TTATCCCAAG TGCTCTTATT 1740
CTGGTβAβAA GAACCTTAAT TCCATAATTT GGGAAGGAAT GGAAGATβGA CACCACCGGA 1800 CACCACCAGA CAATAGGATG GGATGGATGG TTTTTTGGGG GATβββCTAG GGGAAATAAG 1860 βCTTGCTGTT TGTTTTCCTG GGGCGCTCCC TCCAATTTTG CAGATTTTTG CAACCTCCTC 1920 CTGAGCCGGG ATTGTCCAAT TACTAAAATG TAAATAATCA CGTATTGTββ GGAGGGGAGT 1980 TCCAAGTGTG CCCTCCTTTT TTTTCCTGCC TGGATTATTT AAAAAGCCAT GTGTGGAAAC 2040 CCACTATTTA ATAAAAGTAA TAGAATCAGA AAAAAAAAAA AAAAAAAA 2088
Seq ID NO: C95 DNA Sequence
Nucleic Acid Accession ft: NM_002510.1
Coding sequence: 92..1774
11 21 31 41 51
I I I I I
CAGATGCCAG AAGAACACTG TTGCTCTTGG TGGACGGGCC CAGAGGAATT CAGAGTTAAA 60 CCTTGAGTGC CTGCGTCCGT GAGAATTCAG CATGGAATGT CTCTACTATT TCCTGG6ATT 120 TCTGCTCCTG GCTGCAAGAT TGCCACTTGA TGCCGCCAAA CGATTTCATG ATGTGCTGGG 180 CAATGAAAGA CCTTCTGCTT ACATGAGGGA GCACAATCAA TTAAATGGCT GGTCTTCTGA 240 TGAAAATGAC TGGAATGAAA AACTCTACCC AGTGTGGAAG CGGGGAGACA TGAGGTGβAA 300 AAACTCCTGG AAGGGAGGCC GTGTGCAGGC GGTCCTGACC AGTGACTCAC CAGCCCTCGT 360 GGGCTCAAAT ATAACATTTG CGβTGAACCT GATATTCCCT AGATGCCAAA AGGAAGATGC 420 CAATGGCAAC ATAGTCTATG AGAAβAACTβ CAGAAATGAG GCTGGTTTAT CTGCTGATCC 480 ATATGTTTAC AACTGGACAG CATGβTCAGA GGACAGTGAC GGGGAAAATG GCACCCGCCA 540 AAGCCATCAT AACGTCTTCC CTGATββGAA ACCTTTTCCT CACCACCCCG GATβGAGAAG 600 ATGGAATTTC ATCTACGTCT TCCACACACT T∞TCAGTAT TTCCAGAAAT TGGGACGATG 660 TTCAβTGAGA GTTTCTGTGA ACACAGCCAA TGTGACACTT GGGCCTCAAC TCATGGAAGT 720 GACTGTCTAC AGAAGACATG GACGGGCATA TGTTCCCATC GCACAAGTGA AAGATβTβTA 780 CGTGGTAACA GATCAGATTC CTGTGTTTGT βACTATGTTC CAGAAGAACG ATCGAAATTC 840 ATCCGACGAA ACCTTCCTCA AAGATCTCCC CATTATGTTT GATGTCCTGA TTCATGATCC 900 TAGCCACTTC CTCAATTATT CTACCATTAA CTACAAGTGG AGCTTCGGGG ATAATACTGG 960 CCTGTTTGTT TCCACCAATC ATACTGTGAA TCACACGTAT GTGCTCAATG GAACCTTCAG 1020 CCTTAACCTC ACTGTGAAAG CTGCAGCACC AGβACCTTGT CCGCCACCGC CACCACCACC 1080 CAGACCTTCA AAACCCACCC CTTCTTTAGG ACCTGCTGGT GACAACCCCC TGGAGCTGAG 1140 TAGβATTCCT GATGAAAACT GCCAGATTAA CAGATATGGC CACTTTCAAG CCACCATCAC 1200 AATTβTAGAG GGAATCTTAG AGGTTAACAT CATCCAGATG ACAGACGTCC TGATGCCGGT 1260 GCCATGGCCT GAAAGCTCCC TAATAGACTT TGTCGTGACC TGCCAAGGGA GCATTCCCAC 1320
GβAGGTCTGT ACCATCATTT CTGACCCCAC CTGC6AGATC ACCCAGAACA CAGTCTGCAG 1380
CCCTGTGGAT GTGGATGAGA TGTGTCTGCT GACT6TGAGA CGAACCTTCA ATGGGTCTGG 1440
GACGTACTGT GTGAACCTCA CCCTGGGGGA TGACACAAGC CTCβCTCTCA CGAβCACCCT 1500
GATTTCTGTT CCTGACAGAG ACCCAGCCTC GCCTTTAAGG ATGGCAAACA βTGCCCTβAT 1560
CTCCGTTGGC TGCTTGGCCA TATTTGTCAC TGTGATCTCC CTCTTGCTβT ACAAAAAACA 1620
CAAGGAATAC AACCCAATAG AAAATAβTCC TGβGAATGTβ GTCAβAAGCA AAGGCCTGAG 1680
TGTCTTTCTC AACCGTGCAA AAGCCGTGTT CTTCCCGGGA AACCAGGAAA AGGATCCGCT 1740
ACTCAAAAAC CAAGAATTTA AAGGAGTTTC TTAAATTTCG ACCTTGTTTC TGAAGCTCAC 1800
TTTTCAGTGC CATTGATGTG AGATGTGCTG GAGTGGCTAT TAACCTTTTT TTCCTAAAGA 1860
TTATTGTTAA ATAGATATTG TGGTTTGGGG AAGTTGAATT TTTTATAGGT TAAATGTCAT 1920
TTTAGAGATG GGGAGAGGGA TTATACTGCA GGCAGCTTCA GCCATGTTGT GAAACTGATA 1980
AAAGCAACTT AGCAAGβCTT CTTTTCATTA TTTTTTATGT TTCACTTATA AAGTCTTAGG 2040
TAACTAGTAG GATAGAAACA CTGTGTCCCG AGAGTAAGGA GAGAAGCTAC TATTGATTAG 2100
AGCCTAACCC AGGTTAACTG CAAGAAGAGG CGGGATACTT TCAGCTTTCC ATGTAACTGT 2160
ATGCATAAAG CCAATGTAGT CCAGTTTCTA AGATCATGTT CCAAGCTAAC TGAATCCCAC 2220
TTCAATACAC ACTCATGAAC TCCTGATGGA ACAATAACAG GCCCAAGCCT GTGGTATGAT 2280 βTGCACACTT GCTAGACTCA GAAAAAATAC TACTCTCATA AATGGCTGGG AGTATTTTGβ 2340
TGACAACCTA CTTTGCTTGG CTGAGTGAAG GAATGATATT CATATATTCA TTTATTCCAT 2400
GGACATTTAG TTAGTGCTTT TTATATACCA GGCATGATGC TGAGTGACAC TCTTGTGTAT 2460
ATTTCCAAAT TTTTGTATAG TCGCTGCACA TATTTGAAAT CATATATTAA GACTTTCCAA 2520
AGATGAGGTC CCTGGTTTTT CATGGCAACT TGATCAGTAA GGATTTCACC TCTGTTTGTA 2580
ACTAAAACCA TCTACTATAT GTTAGACATG ACATTCTTTT TCTCTCCTTC CTGAAAAATA 2640
AAGTGTGGGA AGAGACAAAA AAAAAAAAA 2669
Seq ID NO: C96 DNA Sequence
Nucleic Acid Accession ff: Eos sequence
Coding sequence: 1—4247
11 21 31 51 I
ATGCCAATCC TAAAGCGTTT CCTCGCTTGC ATTCAGCTCC TCTGTGTTTG CCGCCT66AT 60 TGGGCTAATG GATACTACAG ACAACAGAGA AAACTTGTTβ AAGAβATTβG CTGGTCCTAT 120 ACAGGAGCAC TGAATCAAAA AAATTGGGβA AAβAAATATC CAACATGTAA TAGCCCAAAA 180 CAATCTCCTA TCAATATTGA TGAAGATCTT ACACAAGTAA ATGTGAATCT TAAβAAACTT 240 AAATTTCAGG GTTGGGATAA AACATCATTG GAAAACACAT TCATTCATAA CACTCGGAAA 300 ACAGTGGAAA TTAATCTCAC TAATGACTAC CGTGTCAGCG GAGGAGTTTC AGAAATGGTG 360 TTTAAAGCAA GCAAGATAAC TTTTCACTGG GGAAAATGCA ATATGTCATC TGATGGATCA 420 GAGCATAβTT TAGAAGGACA AAAATTTCCA CTTGAGATGC AAATCTACTG CTTTGATGCA 480 GACCGATTTT CAAGTTTTGA GGAAGCAGTC AAAGGAAAAG GGAAGTTAAG AGCTTTATCC 540 ATTTTGTTTG AGGTTGGGAC AGAAGAAAAT TTGGATTTCA AAGCGATTAT TGATGGAGTC 600 GAAAGTGTTA GTCGTTTTGG GAAGCAGGCT GCTTTAGATC CATTCATACT GTTGAACCTT 660 CTGCCAAACT CAACTGACAA GTATTACATT TACAATGGCT CATTGACATC TCCTCCCTGC 720 ACAGACACAG TTGACTGGAT TGTTTTTAAA GATACAGTTA GCATCTCTGA AAGCCAGTTG 780 GCTGTTTTTT GTGAAGTTCT TACAATGCAA CAATCTGGTT ATGTCAT6CT GATGGACTAC 840 TTACAAAACA ATTTTCGAGA GCAACAGTAC AAGTTCTCTA GACAGGTGTT TTCCTCATAC 900 ACTGβAAAGG AAGAGATTCA TGAAGCAGTT TGTAβTTCAβ AACCAGAAAA TGTTCAGGCT 960 GACCCAGAGA ATTATACCAG CCTTCTTGTT ACATGGGAAA GACCTCGAGT CGTTTATGAT 1020 ACCATGATTβ AGAAGTTTGC AGTTTTGTAC CAGCAGTTGG ATGGAGAGGA CCAAACCAAG 1080 CATGAATTTT TGACAGATGG CTATCAAGAC TTGGGTGCTA TTCTCAATAA TTTGCTACCC 1140 AATATGAGTT ATGTTCTTCA GATAGTAGCC ATATGCACTA ATGGCTTATA TGGAAAATAC 1200 AGCGACCAAC TGATT6TCGA CATGCCTACT GATAATCCTG AACTTGATCT TTTCCCTGAA 1260 TTAATTGGAA CTGAAGAAAT AATCAAGGAβ GAGGAAGAGG βAAAAβACAT TGAAGAAGGC 1320 GCTATTGTGA ATCCTGGTAG AGACAβTβCT ACAAACCAAA TCAGGAAAAA GGAACCCCAG 1380 ATTTCTACCA CAACACACTA CAATCGCATA GGGACGAAAT ACAATGAAGC CAAGACTAAC 1440 CGATCCCCAA CAAGAGGAAG TGAATTCTCT GGAAAGGGTG ATGTTCCCAA TACATCTTTA 1500 AATTCCACTT CCCAACCAGT CACTAAATTA GCCACAGAAA AAGATATTTC CTTGACTTCT 1560 CAGACTβTGA CTGAACTGCC ACCTCACACT GTGGAAGGTA CTTCAGCCTC TTTAAATGAT 1620 GGCTCTAAAA CTGTTCTTAG ATCTCCACAT ATGAACTTGT CGGGGACTGC AGAATCCTTA 1680 AATACAGTTT CTATAACAGA ATATGAGGAG GAGAGTTTAT TGACCAGTTT CAAGCTTGAT 1740 ACTGGAGCTG AAGATTCTTC AGGCTCCAGT CCCGCAACTT CTGCTATCCC ATTCATCTCT 1800 GAGAACATAT CCCAAGGGTA TATATTTTCC TCCβAAAACC CAGAGACAAT AACATATGAT 1860 GTCCTTATAC CAGAATCTGC TAGAAATGCT TCCGAAGATT CAACTTCATC AGGTTCAGAA 1920 GAATCACTAA AGGATCCTTC TATGGAGGGA AATGTGTGGT TTCCTAGCTC TACAGACATA 1980 ACAGCACAGC CCGATGTTGG ATCAGGCAGA GAGAGCTTTC TCCAGACTAA TTACACTGAG 2040 ATACGTGTTG ATGAATCTGA GAAGACAACC AAGTCCTTTT CTGCAGGCCC AGTGATβTCA 2100 CAGβGTCCCT CAGTTACAGA TCTGGAAATG CCACATTATT CTACCTTTGC CTACTTCCCA 2160 ACTGAGGTAA CACCTCATGC TTTTACCCCA TCCTCCAGAC AACAGGATTT GGTCTCCACG 2220 GTCAACGTGG TATACTCGCA GACAACCCAA CCGGTATACA ATGAGGCCAG TAATAβTAβC 2280 CATGAGTCTC GTATTGGTCT AGCTβAGGGG TTGGAATCCG AGAAGAAGGG ACTTATACCC 2340 CTTGTGATCG TGTCAGCCCT GACTTTTATC TGTCTAGTGβ TTCTTGTGGG TATTCTCATC 2400 TACTGGAGGA AATGCTTCCA GACTGCACAC TTTTACTTAβ AGGACAGTAC ATCCCCTAGA 2460 GTTATATCCA CACCTCCAAC ACCTATCTTT CCAATTTCAG ATGATGTCGG AGCAATTCCA 2520 ATAAAGCACT TTCCAAAGCA TGTTGCAGAT TTACATGCAA GTAGTGGGTT TACTGAAGAA 2580 TTTGAGGAAG TGCAGAGCTG TACTβTTGAC 1 TTAGGTATTA CAGCAGACAG CTCCAACCAC 2640 CCAGACAACA AGCACAAGAA TCGATACATA . AATATCGTTG CCTATGATCA TAβCAGGGTT 2700 AAGCTAGCAC AGCTTGCTGA AAAGGATGGC ! AAACTGACTG ATTATATCAA TGCCAATTAT 2760 GTTβATGGCT ACAACAGACC AAAAGCTTAT , ATTGCTGCCC AAGGCCCACT GAAATCCACA 2820 GCTGAAGATT TCTGGAGAAT GATATGGGAA . CATAATGTGG AAGTTATTGT CATGATAACA 2880 AACCTCGTGG AGAAAGGAAG GAGAAAATGT ' GATCAGTACT GGCCTGCCGA TGGGAβTβAG 2940 GAGTACGGGA ACTTTCTGGT CACTCAGAAG 1 AGTGTGCAAG TGCTTGCCTA TTATACTGTG 3000 AGGAATTTTA CTCTAAGAAA CACAAAAATA . AAAAAGGGCT CCCAGAAAGG AAGACCCAGT 3060 GGACGTGTGG TCACACAGTA TCACTACACG 1 CAGTGGCCTG ACATGGGAGT ACCAGAGTAC 3120 TCCCTGCCAG TGCTGACCTT TGTGAGAAAG 1 GCAGCCTATG CCAAGCGCCA TGCAGTGGGG 3180 CCTGTTGTCG TCCACTGCAG TCCTGGAGTT GGAAGAACAG GCACATATAT TGTGCTAGAC 3240
AGTATGTTGC AGCAGATTCA ACACGAAGGA ACTβTCAACA TATTTGGCTT CTTAAAACAC 3300
ATCCGTTCAC AAAGAAATTA TTTGGTACAA ACTGAGGAGC AATATGTCTT CATTCATβAT 3360
ACACTGGTTG AGGCCATACT TAGTAAAGAA ACTGAGGTGC TGGACAGTCA TATTCATGCC 3420
TATGTTAATG CACTCCTCAT TCCTGGACCA GCAGGCAAAA CAAAGCTAGA GAAACAATTC 3480
CAGCTCCTGA GCCAGTCAAA TATACAGCAG AGTGACTATT CTGCAGCCCT AAAGCAATGC 3540
AACAGGGAAA AGAATCGAAC TTCTTCTATC ATCCCTGTGG AAAGATCAAG GGTTGGCATT 3600
TCATCCCTGA GTGGAGAAGβ CACAGACTAC ATCAATGCCT CCTATATCAT GGGCTATTAC 3660
CAGAβCAATG AATTCATCAT TACCCAGCAC CCTCTCCTTC ATACCATCAA GGATTTCTGG 3720
AGGATGATAT GGGACCATAA TGCCCAACTG GTGGTTATβA TTCCTGATGG CCAAAACATG 3780
6CAGAAGATG AATTTGTTTA CTGβCCAAAT AAACATGAGC CTATAAATTG TGAβAGCTTT 3840
AAGGTCACTC TTATGGCTGA AGAACACAAA TGTCTATCTA ATGAGGAAAA ACTTATAATT 3900
CAGGACTTTA TCTTAGAAGC TACACAGGAT GATTATGTAC TTGAAGTGAG GCACTTTCAG 3960
TGTCCTAAAT GGCCAAATCC AGATAGCCCC ATTAGTAAAA CTTTTGAACT TATAAGTGTT 4020
ATAAAAGAAG AAGCTGCCAA TAGGGATGGG CCTATGATTG TTCATGATGA GCATGGAGGA 4080
GTGACGGCAG GAACTTTCTG TGCTCTGACA ACCCTTATGC ACCAACTAGA AAAAGAAAAT 4140
TCCGTGGATG TTTACCAGGT AGCCAAGATG ATCAATCTGA TGAGβCCACβ AGTCTTTGCT 4200
GACATTGAGC AGTATCAGTT TCTCTACAAA GTGATCCTCA βCCTTGTGAG CACAAGGCAG 4260
GAAGAβAATC CATCCACCTC TCTGGACAGT AATGGTGCAG CATTGCCTGA TGGAAATATA 4320 βCTGAGAGCT TAGAGTCTTT AGTTTAA 4347
Seq ID NO: C97 DNA Sequence Nucleic Acid Accession ft : XM_031379 Coding sequence: 148..7095
11 21 31 41
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT βGAGGATTAA . AACAAACAAA 60
CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120
CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180
CAGCTCCTCT GTGTTTGCCβ CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300
AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360
CAAGTAAATβ TCAATCTTAA βAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420
AACACATTCA TTCATAACAC TβββAAAACA GTGGAAATTA ATCTCACTAA TGACTACCGT 480
GTCAGCGGAG GAβTTTCAβA AATβGTGTTT AAAGCAAGCA AGATAACTTT TCACTGGGGA 540
AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600
GAGATGCAAA TCTACTGCTT TβATβCGGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660
GGAAAAGGGA AGTTAAGAβC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720
CATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780
TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840
AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900
ACAGTTAGCA TCTCTGAAAβ CCACTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960
TCTGGTTATG TCATGCTβAT ββACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020
TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGβAAG AGATTCATGA AGCAβTTTGT 1080
AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140
TGGGAAAGAC CTCβAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAβ 1200
CAGTTGGATG GAGAGβACCA AACCAAβCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260
GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAGAT AGTAGCCATA 1320
TGCACTAATG GCTTATATGβ AAAATACAGC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380
AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440
GAAβAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTββTAGAGA CAGTGCTACA 1500
AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAβGG 1560
ACGAAATACA ATGAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGGA 1620
AAGGGTGATG TTCCCAATAC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680
ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740
GAAGGTACTT CAβCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800
AACTTGTCGG GGACTGCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAG 1860
AGTTTATTGA CCAGTTTCAA GCTTGATACT GGAGCTGAAG ATTCTTCAGG CTCCAGTCCC 1920
GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGGGTATAT ATTTTCCTCC 1980
GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG AAATGCTTCC 2040
GAAGATTCAA CTTCATCAGG TTCAGAAβAA TCACTAAAGG ATCCTTCTAT GGAGGGAAAT 2100
GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AβGCAGAGAG 2160
AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAG 2220
TCCTTTTCTG CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280
CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340
TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400
GTATACAATG GTGAGACACC TCTTCAACCT TCCTACAGTA GTGAAGTCTT TCCTCTAGTC 2460
ACCCCTTTGT TGCTTGACAA TCAGATCCTC AACACTACCC CTGCTGCTTC AAGTAGTGAT 2520
TCGGCCTTGC ATGCTACGCC TGTATTTCCC AGTGTCGATG TGTCATTTGA ATCCATCCTG 2580
TCTTCCTATG ATGGTβCACC TTTGCTTCCA TTTTCCTCTG CTTCCTTCAG TAβTGAATTG 2640
TTTCGCCATC TGCATACAβT TTCTCAAATC CTTCCACAAG TTACTTCAGC TACCGAGAGT 2700
GATAAGGTGC CCTTGCATGC TTCTCTβCCA GTGGCTGGGG GTGATTTGCT ATTAβAβCCC 2760
AGCCTTGCTC AGTATTCTGA TGTGCTGTCC ACTACTCATG CTGCTTCAGA GACGCTG6AA 2820
TTTGGTAGTG AATCTββTGT TCTTTATAAA ACGCTTATGT TTTCTCAAGT TGAACCACCC 2880
AGCAGTGATG CCATGATGCA TGCACGTTCT TCAGGGCCTG AACCTTCTTA TGCCTTGTCT 2940
GATAATGAGG GCTCCCAACA CATCTTCACT GTTTCTTACA GTTCTGCAAT ACCTGTβCAT 3000
GATTCTGTGG GTGTAACTTA TCAGGGTTCC TTATTTAGCG GCCCTAGCCA . TATACCAATA 3060
CCTAAGTCTT CGTTAATAAC CCCAACTGCA TCATTACTGC AGCCTACTCA . TGCCCTGTCT 3120
GβTβATGGGG AATGGTCTGG AGCCTCTTCT GATAGTGAAT TTCTTTTACC 1 TGACACAGAT 3180
GGGCTGACAG CCCTTAACAT TTCTTCACCT GTTTCTGTAβ CTβAATTTAC ! ATATACAACA 3240
TCTGTGTTTG GTGATGATAA TAAGGCGCTT TCTAAAAGTG AAATAATATA . TGGAAATGAG 3300
ACTGAACTGC AAATTCCTTC TTTCAATGAG ATGGTTTACC CTTCTGAAAG 1 CACAGTCATG 3360
CCCAACATGT ATGATAATGT AAATAAGTTβ AATGCβTCTT TACAAGAAAC : CTCTGTTTCC 3420 ATTTCTAGCA CCAAGGGCAT GTTTCCAGGG TCCCTTGCTC ATACCACCAC TAAGGTTTTT 3480
GATCATGAβA TTAβTCAAβT TCCAGAAAAT AACTTTTCAG TTCAACCTAC ACATACTGTC 3540
TCTCAAGCAT CTGGTGACAC TTCGGTTAAA CCTGTGCTTA GTGCAAACTC AGAGCCACCA 3600
TCCTCT6ACC CTGCTTCTAG TGAAATGTTA TCTCCTTCAA CTCAGCTCTT ATTTTATGAG 3660
ACCTCAGCTT CTTTTAGTAC TGAAGTATTG CTACAACCTT CCTTTCAGGC TTCTGATGTT 3720
GACACCTTGC TTAAAACTGT TCTTCCACCT βTGCCCAGTG ATCCAATATT GGTTGAAACC 3780
CCCAAACTTG ATAAAATTAG TTCTACAATG TTGCATCTCA TTGTATCAAA TTCTGCTTCA 3840
AGTGAAAACA TGCTGCACTC TACATCTGTA CCAGTTTTTG ATGTβTCGCC TACTTCTCAT 3900
ATGCACTCTG CTTCACTTCA AGβTTTGACC ATTTCCTATG CAAGTGAGAA ATATGAACCA 3960
GTTTTGTTAA AAAGTGAAAG TTCCCACCAA βTβGTACCTT CTTTGTACAβ TAATGATGAG 4020
TTGTTCCAAA CGGCCAATTT GGAGATTAAC CAGGCCCATC CCCCAAAAGG AAGGCATGTA 4080
TTTGCTACAC CTGTTTTATC AATTGATGAA CCATTAAATA CACTAATAAA TAAGCTTATA 4140
CATTCCGATG AAATTTTAAC CTCCACCAAA AGTTCTGTTA CTGGTAAGGT ATTTGCTGGT 4200
ATTCCAACAG TTGCTTCTGA TACATTTGTA TCTACTGATC ATTCTGTTCC TATAGGAAAT 4260
GGGCATGTTG CCATTACAGC TGTTTCTCCC CACAGAGATG GTTCTβTAAC CTCAACAAAG 4320
TTGCTGTTTC CTTCTAAGGC AACTTCTGAG CTβAGTCATA GTβCCAAATC TGATGCCGGT 4380
TTAGTGGGTG βTGGTGAAGA TGβTβACACT CATGATGATG GTβATβATGA TGATGATGAC 4440
AGAGGTAGTG ATGGCTTATC CATTCATAAG TGTATGTCAT GCTCATCCTA TAGAGAATCA 4500
CAGGAAAAGG TAATGAATGA TTCAGACACC CACGAAAACA GTCTTATGGA TCAGAATAAT 4560
CCAATCTCAT ACTCACTATC TGAGAATTCT βAAGAAGATA ATAGAGTCAC AAGTGTATCC 4620
TCAGACAGTC AAACTGGTAT GβACAβAAβT CCTβGTAAAT CACCATCAGC AAATGGGCTA 4680
TCCCAAAAGC ACAATGATGG AAAAGAGGAA AATGACATTC AGACTGGTAG TGCTCTGCTT 4740
CCTCTCAGCC CTGAATCTAA AGCATGGGCA GTTCTGACAA GTGATGAAβA AAGTGGATCA 4800
GGGCAAGGTA CCTCAGATAβ CCTTAATGAG AATGAGACTT CCACAGATTT CA6TTTTGCA 4860
GACACTAATG AAAAAGATβC TGATGGGATC CTGGCAGCAG GTGACTCAGA AATAACTCCT 4920
GGATTCCCAC AGTCCCCAAC ATCATCTGTTi ACTAGCGAGA ACTCAGAAGT GTTCCACGTT 980
TCAGAGGCAG AGGCCAGTAA TAGTAGCCAT GAGTCTCGTA TTGGTCTAGC TGAGGGGTTG 5040
GAATCCGAGA AGAAGGCAGT TATACCCCTT GTGATCGTGT CAGCCCTGAC TTTTATCTGT 5100
CTAGTGGTTC TTGTGGGTAT TCTCATCTAC TGGAGGAAAT GCTTCCAGAC TβCACACTTT 5160
TACTTAGAGG ACAGTACATC CCCTAGAGTT ATATCCACAC CTCCAACACC TATCTTTCCA 5220
ATTTCAGATG ATGTCGGAGC AATTCCAATA AAGCACTTTC CAAAGCATGT TGCA6ATTTA 5280
CATGCAAGTA GTGGGTTTAC TGAAGAATTT GAGACACTGA AAGAGTTTTA CCAGGAAGTG 5340
CAGAGCTGTA CTGTTGACTT AGGTATTACA GCAGACAGCT CCAACCACCC AGACAACAAG' 5400
CACAAGAATC GATACATAAA TATCGTTGCC TATGATCATA GCAGGGTTAA GCTAβCACAG 5460
CTTGCTGAAA AGGATβCCAA ACTβACTGAT TATATCAATG CCAATTATGT TGATβGCTAC 5520
AACAGACCAA AAGCTTATAT TGCTGCCCAA GGCCCACTGA AATCCACAGC TGAA6ATTTC 5580
TGGAGAATGA TATGGGAACA TAATGTGGAA GTTATTGTCA TGATAACAAA CCTCGTGGAG 5640
AAAGGAAGGA GAAAATGTβA TCAβTACTGG CCTCCCCATG GGAGTGAGGA GTACGGGAAC 5700
TTTCTGβTCA CTCAGAAGAG TGTGCAAβTG CTTGCCTATT ATACTGTGAG GAATTTTACT 5760
CTAAβAAACA CAAAAATAAA AAAGGβCTCC CACAAAββAA GACCCAGTGG ACGTGTβGTC 5820
ACACAGTATC ACTACACGCA βTGGCCTGAC ATGGGAGTAC CAGAGTACTC CCTGCCAGTG 5880
CTGACCTTTG TGAGAAAGGC AGCCTATGCC AAGCGCCATG CAGTGGGGCC TGTTGTCGTC 5940
CACTGCAGTβ CTGGAGTTGβ AAGAACA6GC ACATATATTG TGCTAGACAG TATGTTGCAG 6000
CAGATTCAAC ACGAAGGAAC TGTCAACATA TTTGGCTTCT TAAAACACAT CCGTTCACAA 6060
AGAAATTATT TGGTACAAAC TGAGGAGCAA TATGTCTTCA TTCATGATAC ACTGGTTGAG 6120
GCCATACTTA GTAAAGAAAC TGAGGTGCTG GACAGTCATA TTCATGCCTA TβTTAATGCA 6180
CTCCTCATTC CTGGACCAGC AGGCAAAACA AAGCTAGAGA AACAATTCCA GCTCCTGAGC 6240
CAGTCAAATA TACAGCAGAG TGACTATTCT GCAβCCCTAA AGCAATGCAA CAGGGAAAAG 6300
AATCGAACTT CTTCTATCAT CCCTGTGGAA AGATCAAGGG TTGGCATTTC ATCCCTGAGT 6360
GGAGAAGGCA CAGACTACAT CAATGCCTCC TATATCATGG GCTATTACCA GAGCAATGAA 6420
TTCATCATTA CCCAGCACCC TCTCCTTCAT ACCATCAAGG ATTTCTGGAG GATGATATββ 6480
GACCATAATG CCCAACTGGT GGTTATGATT CCTGATGGCC AAAACATG6C AGAAGATGAA 6540
TTTGTTTACT GGCCAAATAA AGATGAGCCT ATAAATTGTG AGAGCTTTAA GGTCACTCTT 6600
ATGGCTGAAG AACACAAATG TCTATCTAAT GAGGAAAAAC TTATAATTCA GβACTTTATC 6660
TTAGAAGCTA CACAGGATGA TTATGTACTT GAAGTGAGGC ACTTTCAGTG TCCTAAATGG 6720
CCAAATCCAG ATAGCCCCAT TAGTAAAACT TTTGAACTTA TAAGTβTTAT AAAAGAAβAA 6780
GCTGCCAATA GGGATGGGCC TATGATTGTT CATGATGAGC ATGGAGGAGT GACGβCAGGA 6840
ACTTTCTGTG CTCTGACAAC CCTTATGCAC CAACTAGAAA AAGAAAATTC CGTGGATGTT 6900
TACCAGGTAG CCAAGATGAT CAATCTGATG AGGCCAGGAG TCTTTGCTGA CATTGAGCAβ 6960
TATCAGTTTC TCTACAAAGT GATCCTCAGC CTTGTGAGCA CAAGGCAGGA AGAGAATCCA 7020
TCCACCTCTC TGGACAGTAA TGGTβCACCA TTGCCTGATG GAAATATAGC TGAGAGCTTA 7080
GAGTCTTTAG TTTAACACAG AAAGGββTGG GGGGACTCAC ATCTβAβCAT TGTTTTCCTC 7140
TTCCTAAAAT TAGGCAGGAA AATCAGTCTA GTTCTβTTAT CTGTTGATTT CCCATCACCT 7200
GACAGTAACT TTCATGACAT AGGATTCTGC CGCCAAATTT ATATCATTAA CAATGTGTGC 7260
CTTTTTGCAA GACTTGTAAT TTACTTATTA TGTTTGAACT AAAATGATTG AATTTTACAG 7320
TATTTCTAAG AATGGAATTβ TGGTATTTTT TTCTGTATTG ATTTTAACAG AAAATTTCAA 7380
TTTATAGAGG TTAGGAATTC CAAACTACAG AAAATGTTTG TTTTTAGT6T CAAATTTTTA 7440
GCTGTATTTG TAGCAATTAT CAG6TTTGCT AGAAATATAA CTTTTAATAC AGTAGCCTGT 7500
AAATAAAACA CTCTTCCATA TGATATTCAA CATTTTACAA CTGCAGTATT CACCTAAAGT 7560
AGAAATAATC TGTTACTTAT TGTAAATACT GCCCTAGTGT CTCCATGβAC CAAATTTATA 7620
TTTATAATTG TAGATTTTTA TATTTTACTA CTGAGTCAAG TTTTCTAGTT CTGTGTAATT 7680
GTTTAGTTTA ATGACGTAGT TCATTAGCTG GTCTTACTCT ACCAGTTTTC TGACATTGTA 7740
TTGTGTTACC TAAGTCATTA ACTTTGTTTC AGCATGTAAT TTTAACTTTT GTGGAAAATA 7800
GAAATACCTT CATTTTGAAA GAAGTTTTTA TβAGAATAAC ACCTTACCAA ACATTGTTCA 7860
AATGGTTTTT ATCCAAGGAA TTGCAAAAAT AAATATAAAT ATTGCCATTA AAAAAAAAAA 7920
AAAAAAAAAA AAAAAAAAAA AAAA 7944
Seq ID NO: C98 DNA Sequence Nucleic Acid Accession ft: NM_002851 Coding sequence: 77..4518
1 11 21 31 41 51
I I I I I I
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60 CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGGAGCCGCA 120
CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180
CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGβAAAG 300
AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360
CAAGTAAATG TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420
AACACATTCA TTCATAACAC TGGβAAAACA GTGβAAATTA ATCTCACTAA TβACTACCGT 480
GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AβATAACTTT TCACTCGGGA 540
AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600
GAGATGCAAA TCTACTGCTT TGATGCGGAC CGATTTTCAA GTTTTGAGGA AGCACTGAAA 660
G6AAAA6GGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720
GATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780
TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840
AATβGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900
ACAGTTAβCA TCTCTβAAAG CCAGTTGGCT GTTTTTTGTG AAGTTCTTAC AATGCAACAA 960
TCTGGTTATG TCATGCTGAT GGACTACTTA CAAAACAATT TTCGAGAGCA ACAGTACAAG 1020
TTCTCTAGAC AGGTGTTTTC CTCATACACT GGAAAGGAAG AGATTCATGA AGCAGTTTGT 1080
AGTTCAGAAC CAGAAAATGT TCAGGCTGAC CCAGAGAATT ATACCAGCCT TCTTGTTACA 1140
TGGGAAAGAC CTCGAGTCGT TTATGATACC ATGATTGAGA AGTTTGCAGT TTTGTACCAG 1200
CAGTTGGATβ GAGAGGACCA AACCAAGCAT GAATTTTTGA CAGATGGCTA TCAAGACTTG 1260
GGTGCTATTC TCAATAATTT GCTACCCAAT ATGAGTTATG TTCTTCAβAT AGTAGCCATA 1320
TGCACTAATG GCTTATATGG AAAATACAGC GACCAACTGA TTGTCGACAT GCCTACTGAT 1380
AATCCTGAAC TTGATCTTTT CCCTGAATTA ATTGGAACTG AAGAAATAAT CAAGGAGGAG 1440
GAAGAGGGAA AAGACATTGA AGAAGGCGCT ATTGTGAATC CTGGTAGAGA CAGTGCTACA 1500
AACCAAATCA GGAAAAAGGA ACCCCAGATT TCTACCACAA CACACTACAA TCGCATAGGβ 1560
ACGAAATACA ATGAAGCCAA GACTAACCGA TCCCCAACAA GAGGAAGTGA ATTCTCTGβA 1620
AAGGGTGATG TTCCCAATAC ATCTTTAAAT TCCACTTCCC AACCAGTCAC TAAATTAGCC 1680
ACAGAAAAAG ATATTTCCTT GACTTCTCAG ACTGTGACTG AACTGCCACC TCACACTGTG 1740
GAAGGTACTT CAGCCTCTTT AAATGATGGC TCTAAAACTG TTCTTAGATC TCCACATATG 1800
AACTTGTCGG GGACTGCAGA ATCCTTAAAT ACAGTTTCTA TAACAGAATA TGAGGAGGAβ 1860
AGTTTATTGA CCAGTTTCAA GCTTGATACT GGAGCTGAAβ ATTCTTCAGG CTCCAGTCCC 1920
GCAACTTCTG CTATCCCATT CATCTCTGAG AACATATCCC AAGGGTATAT ATTTTCCTCC 1980
GAAAACCCAG AGACAATAAC ATATGATGTC CTTATACCAG AATCTGCTAG AAATGCTTCC 2040
GAAGATTCAA CTTCATCAGG TTCAGAAGAA TCACTAAAββ ATCCTTCTAT βGAGGGAAAT 2100
GTGTGGTTTC CTAGCTCTAC AGACATAACA GCACAGCCCG ATGTTGGATC AGβCAGAGAG 2160
AGCTTTCTCC AGACTAATTA CACTGAGATA CGTGTTGATG AATCTGAGAA GACAACCAAβ 2220
TCCTTTTCTβ CAGGCCCAGT GATGTCACAG GGTCCCTCAG TTACAGATCT GGAAATGCCA 2280
CATTATTCTA CCTTTGCCTA CTTCCCAACT GAGGTAACAC CTCATGCTTT TACCCCATCC 2340
TCCAGACAAC AGGATTTGGT CTCCACGGTC AACGTGGTAT ACTCGCAGAC AACCCAACCG 2400
GTATACAATG CAGAGGCCAG TAATAGTAGC CATGAGTCTC GTATTGGTCT AGCTGAGGGG 2460
TTGGAATCCG AGAAGAAGGC AGTTATACCC CTTGTGATCG TGTCAGCCCT GACTTTTATC 2520
TCTCTACTGG TTCTTGTCGG TATTCTCATC TACTGGAGGA AATGCTTCCA GACTGCACAC 2580
TTTTACTTAG AGGACAGTAC ATCCCCTAGA GTTATATCCA CACCTCCAAC ACCTATCTTT 2640
CCAATTTCAG ATGATGTCGG AGCAATTCCA ATAAAGCACT TTCCAAAGCA TGTTGCAGAT 2700
TTACATGCAA GTAGTGGGTT TACTGAAGAA TTTGAGACAC TGAAAGAGTT TTACCAGGAA 2760
GTβCAGAGCT GTACTGTTGA CTTAGGTATT ACAGCAGACA GCTCCAACCA CCCAGACAAC 2820
AAGCACAAGA ATCGATACAT AAATATCGTT GCCTATGATC ATAGCAGGGT TAAGCTAGCA 2880
CAGCTTGCTC AAAAGGATGG CAAACTGACT GATTATATCA ATGCCAATTA TGTTGATGβC 2940
TACAACAGAC CAAAAβCTTA TATTβCTGCC CAAGGCCCAC TGAAATCCAC AGCTGAAGAT 3000
TTCTGGAGAA TGATATGGGA ACATAATGTG GAAGTTATTG TCATGATAAC AAACCTCGTG 3060
GAGAAAβGAA GGAGAAAATG TGATCAGTAC TGGCCTGCCG ATGGGAGTβA GGAGTACGGG 3120
AACTTTCTGG TCACTCAGAA GAGTGTGCAA GTGCTTGCCT ATTATACTGT GAGGAATTTT 3180
ACTCTAAGAA ACACAAAAAT AAAAAAGGGC TCCCAGAAAG GAAGACCCAG TGGACGTGTG 3240
GTCACACAGT ATCACTACAC GCAGTGGCCT GACATGGGAG TACCAGAGTA CTCCCTGCCA 3300
GTGCTGACCT TTGTGAGAAA GGCAGCCTAT GCCAAGCGCC ATGCAGTGGG GCCTGTTGTC 3360
GTCCACT6CA GTGCTGGAGT TGGAAGAACA GβCACATATA TTGTGCTAGA CAGTATGTTG 3420
GAGCAGATTC AACACβAAGG AACTGTCAAC ATATTTGGCT TCTTAAAACA CATCCGTTCA 3480
CAAAGAAATT ATTTGGTACA AACTβAβGAG CAATATGTCT TCATTCATGA TACACTGGTT 3540
GAGGCCATAC TTAGTAAAGA AACTGAGGTG CTGGACAGTC ATATTCATGC CTATGTTAAT 3600
GCACTCCTCA TTCCTGGACC AGCAGGCAAA ACAAAGCTAG AGAAACAATT CCAGCTCCTG 3660
AGCCAGTCAA ATATACAGCA GAGTGACTAT TCTGCAGCCC TAAAGCAATG CAACAGGGAA 3720
AAGAATCGAA CTTCTTCTAT CATCCCTGTG GAAAGATCAA GGGTTGGCAT TTCATCCCTG 3780
AGTGGAGAAG βCACAGACTA CATCAATGCC TCCTATATCA TGGGCTATTA CCAGAGCAAT 3840
GAATTCATCA TTACCCAGCA CCCTCTCCTT CATACCATCA AGβATTTCTβ GAGGATGATA 3900
TGGGACCATA ATGCCCAACT GGTGGTTATG ATTCCTGATG GCCAAAACAT GGCAGAAGAT 3960
GAATTTGTTT ACTGGCCAAA TAAAGATGAG CCTATAAATT GTGAGAβCTT TAAGGTCACT 4020
CTTATGβCTG AAGAACACAA ATGTCTATCT AATGAβGAAA AACTTATAAT TCAGGACTTT 4080
ATCTTAGAAG CTACACAGGA TGATTATGTA CTTGAAGTGA GβCACTTTCA GTGTCCTAAA 4140
TGGCCAAATC CAGATAGCCC CATTAGTAAA ACTTTTGAAC TTATAAGTGT TATAAAAGAA 4200
GAAGCTGCCA ATAβGGATGG GCCTATβATT GTTCATGATG AGCATGGAGG AGTGACGGCA 4260
GGAACTTTCT GTGCTCTGAC AACCCTTATG CACCAACTAG AAAAAGAAAA TTCCGTGGAT 4320
GTTTACCAGG TAGCCAAGAT GATCAATCTG ATGAGGCCAG GACTCTTTGC TGACATTGAG 4380
CAGTATCAGT TTCTCTACAA AGTGATCCTC AGCCTTGTGA GCACAAGGCA GGAAGAGAAT 4440
CCATCCACCT CTCTGGACAG TAATGGTGCA GCATTGCCTG ATGGAAATAT AGCTGAGAGC 4500
TTAGAGTCTT TAGTTTAACA CAGAAAGGGG TGGGGGGACT CACATCTGAG CATTGTTTTC 4560 CTCTTCCTAA AATTAGGCAG GAAAATCAGT CTAGTTCTGT TATCTGTTGA TTTCCCATCA 4620 CCTGACAGTA ACTTTCATGA CATAGGATTC TGCCGCCAAA TTTATATCAT TAACAATGTG 4680 TGCCTTTTTG CAAGACTTGT AATTTACTTA TTATGTTTGA ACTAAAATGA TTGAATTTTA 4740 CAGTATTTCT AAGAATGGAA TTGTGGTATT TTTTTCTGTA TTGATTTTAA CAGAAAATTT 4800 CAATTTATAβ AGGTTAGGAA TTCCAAACTA CAGAAAATGT TTGTTTTTAG TGTCAAATTT 4860 TTACCTGTAT TTGTAGCAAT TATCAGGTTT GCTAGAAATA TAACTTTTAA TACAGTAGCC 4920 TGTAAATAAA ACACTCTTCC ATATβATATT CAACATTTTA CAACTGCAGT ATTCACCTAA 4980 AGTAGAAATA ATCTGTTACT TATTGTAAAT ACTGCCCTAG TGTCTCCATG GACCAAATTT 5040 ATATTTATAA TTGTAGATTT TTATATTTTA CTACTGAGTC AAGTTTTCTA GTTCTGTGTA 5100 ATTGTTTAGT TTAATGACGT AGTTCATTAG CTGGTCTTAC TCTACCAGTT TTCTGACATT 5160
GTATTGTGTT ACCTAAGTCA TTAACTTTGT TTCAGCATGT AATTTTAACT TTTGTGGAAA 5220
ATAGAAATAC CTTCATTTTG AAAGAAGTTT TTATGAGAAT AACACCTTAC CAAACATTGT 5280
TCAAATGGTT TTTATCCAAG GAATTGGAAA AATAAATATA AATATTGCCA TTAAAAAAAA 5340
AAAAAAAAAA AAAAAAAAAA AAAAAAA 5367
Seq ID NO : C99 DNA Sequence
Nucleic Acid Accession # : Eos sequence
Coding sequence : 501 . .4514
1 11 21 31 41 51
I I I I I I
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60
CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAG AGβAβCCβCA 120
CGGCGAGG6G CCGCAGACCG TCTGGAAATG CGAATCCTAA AGCGTTTCCT CGCTTGCATT 180
CAGCTCCTCT GTGTTTGCCG CCTGGATTGG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG βTCCTATACA GGAGCACTGA ATCAAAAAAT TGGGGAAAGA 300
AATATCCAAC ATGTAATAβC CCAAAACAAT CTCCTATCAA TATTGATGAA GATCTTACAC 360
AAGTAAATGT GAATCTTAAG AAACTTAAAT TTCAGGGTTG GGATAAAACA TCATTGGAAA 420
ACACATTCAT TCATAACACT GGGAAAACAG TGGAAATTAA TCTCACTAAT GACTACCGTG 480
TCAGCGGAGG AGTTTCAβAA ATβGTGTTTA AAGCAAGCAA GATAACTTTT CACTGGGGAA 540
AATGCAATAT GTCATCTGAT GGATCAβAβC ATAGTTTAGA AGGACAAAAA TTTCCACTTG 600
AGATGCAAAT CTACTGCTTT GATGCGGACC GATTTTCAAG TTTTGAGGAA GCAGTCAAAG 660
GAAAAGGGAA GTTAAGAGCT TTATCCATTT TGTTTGAGGT TGGGACAGAA GAAAATTTGG 720
ATTTCAAAGC GATTATTGAT GGAGTCGAAA GTGTTAGTC6 TTTTGββAAβ CAββCTGCTT 780
TAGATCCATT CATACTGTTβ AACCTTCTβC CAAACTCAAC TGACAAGTAT TACATTTACA 840
ATGGCTCATT GACATCTCCT CCCTGCACAG ACACAGTTGA CTGGATTGTT TTTAAAGATA 900
CAGTTAGCAT CTCTGAAAGC CAβTTGGCTG TTTTTTGTGA AGTTCTTACA ATGCAACAAT 960
CTGGTTATGT CATGCTGATG GACTACTTAC AAAACAATTT TCGAGAGCAA CAGTACAAGT 1020
TCTCTAGACA GGTGTTTTCC TCATACACTG GAAAGGAAGA GATTCATGAA GCAGTTTGTA 1080
GTTCAβAACC AGAAAATGTT CAGGCTGACC CAGAGAATTA TACCAβCCTT CTTGTTACAT 1140
GGGAAAGACC TCGAGTCGTT TATGATACCA TGATTGAGAA GTTTβCAGTT TTGTACCAβC 1200
AGTTGGATGG AGAGGACCAA ACCAAGCATG AATTTTTGAC AGATGGCTAT CAAGACTTGG 1260
GTGCTATTCT CAATAATTTG CTACCCAATA TGAGTTATGT TCTTCAGATA GTAGCCATAT 1320
GCACTAATβG CTTATATGGA AAATACAGCG ACCAACTGAT TβTCβACATG CCTACTGATA 1380
ATCCTGAACT TGATCTTTTC CCTGAATTAA TTGGAACTGA AGAAATAATC AAGGAGGAGG 1440
AAGAβGGAAA AGACATTGAA GAAGGCGCTA TTGTGAATCC TGGTAGAGAC AGTGCTACAA 1500
ACCAAATCAC GAAAAAGGAA CCCCAGATTT CTACCACAAC ACACTACAAT CGCATAGGGA 1560
CGAAATACAA TGAAGCCAAG ACTAACCGAT CCCCAACAAG AGGAAGT6AA TTCTCTGGAA 1620
AGGGTGATGT TCCCAATACA TCTTTAAATT CCACTTCCCA ACCAGTCACT AAATTAGCCA 1680
CAGAAAAAGA TATTTCCTTG ACTTCTCAGA CTGTGACTGA ACTGCCACCT CACACTGTGG 1740
AAGGTACTTC AGCCTCTTTA AATGATGGCT CTAAAACTβT TCTTAβATCT CCACATATGA 1800
ACTTGTCGβG GACTGCAGAA TCCTTAAATA CAGTTTCTAT AACAGAATAT GAGGAGGAGA 1860
GTTTATTGAC CAGTTTCAAG CTTGATACTG βAβCTβAAGA TTCTTCAGGC TCCAGTCCCG 1920
CAACTTCTGC TATCCCATTC ATCTCTGAGA ACATATCCCA AGGGTATATA TTTTCCTCCG 1980
AAAACCCAGA GACAATAACA TATGATGTCC TTATACCAGA ATCTGCTAGA AATGCTTCCG 2040
AAGATTCAAC TTCATCAGGT TCAGAAGAAT CACTAAAGGA TCCTTCTATG GAGGGAAATG 2100
TGTGGTTTCC TAGCTCTACA GACATAACAG CACAGCCCGA TGTTGGATCA GGCAGAGAGA 2160
GCTTTCTCCA βACTAATTAC ACTGAGATAC GTβTTβATGA ATCTGAGAAG ACAACCAAGT 2220
CCTTTTCTGC AGβCCCAGTG ATGTCACAGG GTCCCTCAGT TACAβATCTG GAAAT6CCAC 2280
ATTATTCTAC CTTTGCCTAC TTCCCAACTβ AGGTAACACC TCATGCTTTT ACCCCATCCT 2340
CCAGACAACA GGATTTGGTC TCCACGGTCA ACGTGGTATA CTCGCAGACA ACCCAACCGG 2400
TATACAATβA GGCCAGTAAT AGTAGCCATG AGTCTCGTAT TGGTCTAGCT GAGGGGTTGG 2460
AATCCGAGAA GAAGGCAGTT ATACCCCTTG TGATCGTGTC AGCCCTGACT TTTATCTGTC 2520
TAGTGGTTCT TGTGGGTATT CTCATCTACT GGAGGAAATG CTTCCAGACT GCACACTTTT 2580
ACTTAGAGGA CAGTACATCC CCTAGAGTTA TATCCACACC TCCAACACCT ATCTTTCCAA 2640
TTTCAGATβA TGTCGGAGCA ATTCCAATAA AGCACTTTCC AAAGCATGTT GCAGATTTAC 2700
ATGCAAGTAG TβGGTTTACT GAAGAATTTG AGACACTGAA AβAβTTTTAC CAGGAAGTGC 2760
AGAGCTGTAC TGTTGACTTA GβTATTACAβ CAGACAGCTC CAACCACCCA GACAACAAGC 2820
ACAAGAATCG ATACATAAAT ATCGTTGCCT ATGATCATAG CAGGGTTAAG CTAβCACAGC 2880
TTGCTGAAAA GGATGGCAAA CTGACTGATT ATATCAATGC CAATTATGTT GATGGCTACA 2940
ACAGACCAAA AGCTTATATT CCTGCCCAAG GCCCACTGAA ATCCACAGCT GAAGATTTCT 3000
GGAGAATGAT ATGGGAACAT AATGTGGAAG TTATTGTCAT βATAACAAAC CTCβTGGAGA 3060
AAGGAAGGAG AAAATGTGAT CAGTACTβGC CTGCCGATGG GAGTGAGGAG TACGGGAACT 3120
TTCTGGTCAC TCAGAAGAGT GTGCAAGTβC TTGCCTATTA TACTGTGAGG AATTTTACTC 3180
TAAGAAACAC AAAAATAAAA AAGGGCTCCC AGAAAGGAAG ACCCAGTGGA CGTGTββTCA 3240
CACAGTATCA CTACACGCAG TGGCCTGACA TGGGAGTACC AGAGTACTCC CTGCCAGTGC 3300
TGACCTTTGT GAGAAAGGCA GCCTATGCCA AGCGCCATGC AGTGGGGCCT GTTGTCGTCC 3360
ACTGCAGTGC TGGAGTTGGA AGAACAGGCA CATATATTGT GCTAGACAGT ATGTTGCAGC 3420
AGATTCAACA CGAAGGAACT GTCAACATAT TTGGCTTCTT AAAACACATC CGTTCACAAA 3480
GAAATTATTT GGTACAAACT GAGGAGCAAT ATGTCTTCAT TCATGATACA CTGGTTGAGG 3540
CCATACTTAG TAAAGAAACT 6AGGTGCTGG ACAGTCATAT TCATGCCTAT GTTAATGCAC 3600
TCCTCATTCC TGGACCACCA GGCAAAACAA AGCTAGAGAA ACAATTCCAG CTCCTGAGCC 3660
AGTCAAATAT ACAGCAGAβT GACTATTCTG CAGCCCTAAA GCAATGCAAC AβGGAAAAGA 3720
ATCGAACTTC TTCTATCATC CCTGTGGAAA GATCAAGGGT TGGCATTTCA TCCCTGAGTG 3780
GAGAAGβCAC AβACTACATC AATGCCTCCT ATATCATGGG CTATTACCAG AGCAATGAAT 3840
TCATCATTAC CCAGCACCCT CTCCTTCATA CCATCAAGGA TTTCTGGAGG ATGATATGGG 3900
ACCATAATGC CCAACTGGTG GTTATGATTC CTGATGGCCA AAACATGGCA GAAβATβAAT 3960
TTGTTTACTG GCCAAATAAA GATGAGCCTA TAAATTGTGA GAGCTTTAAβ βTCACTCTTA 4020
TGGCTGAAGA ACACAAAT6T CTATCTAATG AGGAAAAACT TATAATTCAG GACTTTATCT 4080
TAGAAGCTAC ACAGGATGAT TATGTACTTG AAGTGAGGCA CTTTCAGTGT CCTAAATGGC 4140
CAAATCCAGA TAGCCCCATT AGTAAAACTT TTGAACTTAT AAGTGTTATA AAAGAAGAAG 4200
CTGCCAATAG GGATGGGCCT ATGATTGTTC ATGATGAGCA TGGAGGAGTG ACGGCAGGAA 4260
CTTTCTGTGC TCTGACAACC CTTATGCACC AACTAGAAAA AGAAAATTCC GTGβATGTTT 4320 ACCAGGTAGC CAAGATGATC AATCTGATGA GGCCAGGAGT CTTTGCTGAC ATTGAGCAGT 4380
ATCAGTTTCT CTACAAAGTG ATCCTCAGCC TTGTGAGCAC AAGGCAGGAA GAGAATCCAT 4440
CCACCTCTCT GGACAGTAAT GGTGCAGCAT TGCCTGATGG AAATATAGCT GA6AGCTTAG 4500
AGTCTTTAGT TTAACACAGA AAGGGGTGGG GGGACTCACA TCTGAGCATT GTTTTCCTCT 4560
TCCTAAAATT AGGCAGGAAA ATCAGTCTAG TTCTGTTATC TGTTGATTTC CCATCACCTG 4620
ACAGTAACTT TCATGACATA GGATTCTGCC GCCAAATTTA TATCATTAAC AATβTβTβCC 4680
TTTTTGCAAG ACTTGTAATT TACTTATTAT βTTTGAACTA AAATβATTGA ATTTTACAGT 4740
ATTTCTAAGA ATGGAATTGT GGTATTTTTT TCTGTATTGA TTTTAACAGA AAATTTCAAT 4800
TTATAGAGGT TAGGAATTCC AAACTACAGA AAATGTTTGT TTTTAGTGTC AAATTTTTAG 4860
CTGTATTTGT AGCAATTATC AGGTTTGCTA GAAATATAAC TTTTAATACA CTAβCCTGTA 4920
AATAAAACAC TCTTCCATAT GATATTCAAC ATTTTACAAC TGCAGTATTC ACCTAAAGTA 4980
GAAATAATCT GTTACTTATT GTAAATACTG CCCTAβTβTC TCCATGGACC AAATTTATAT 5040
TTATAATTGT AGATTTTTAT ATTTTACTAC TGAGTCAACT TTTCTAβTTC TGTGTAATTG 5100
TTTAGTTTAA TGACGTAGTT CATTAGCTGG TCTTACTCTA CCAGTTTTCT GACATTGTAT 5160
TGTGTTACCT AAGTCATTAA CTTTβTTTCA GCATGTAATT TTAACTTTTG TGGAAAATAG 5220
AAATACCTTC ATTTTGAAAG AAGTTTTTAT GAβAATAACA CCTTACCAAA CATTGTTCAA 5280
ATGGTTTTTA TCCAAGGAAT TGCAAAAATA AATATAAATA TTGCCATTAA AAAAAAAAAA 5340
AAAAAAAAAA AAAAAAAAAA AAA 5363
Seq ID NO: C100 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 148..4362 1 11 21 31 41 51 i i i i i i
CACACATACG CACGCACGAT CTCACTTCGA TCTATACACT GGAGGATTAA AACAAACAAA 60
CAAAAAAAAC ATTTCCTTCG CTCCCCCTCC CTCTCCACTC TGAGAAGCAβ AGGAGCCGCA 120
CGGCGAGGGG CCGCAGACCG TCTGGAAATG CGAATCCTAA AACGTTTCCT CGCTTβCATT 180
CAβCTCCTCT GTGTTTGCCG CCTGβATTβG GCTAATGGAT ACTACAGACA ACAGAGAAAA 240
CTTGTTGAAG AGATTGGCTG GTCCTATACA GGAGCACTGA ATCAAAAAAA TTGGGGAAAG 300
AAATATCCAA CATGTAATAG CCCAAAACAA TCTCCTATCA ATATTGATGA AGATCTTACA 360
CAAGTAAATβ TGAATCTTAA GAAACTTAAA TTTCAGGGTT GGGATAAAAC ATCATTGGAA 420
AACACATTCA TTCATAACAC TGGGAAAACA GTGGAAATTA ATCTCACTAA TGACTACCβT 480
GTCAGCGGAG GAGTTTCAGA AATGGTGTTT AAAGCAAGCA AGATAACTTT TCACTG6GGA 540
AAATGCAATA TGTCATCTGA TGGATCAGAG CATAGTTTAG AAGGACAAAA ATTTCCACTT 600
GAGATGCAAA TCTACTGCTT TGATGCGGAC CGATTTTCAA GTTTTGAGGA AGCAGTCAAA 660
GGAAAAGGGA AGTTAAGAGC TTTATCCATT TTGTTTGAGG TTGGGACAGA AGAAAATTTG 720
GATTTCAAAG CGATTATTGA TGGAGTCGAA AGTGTTAGTC GTTTTGGGAA GCAGGCTGCT 780
TTAGATCCAT TCATACTGTT GAACCTTCTG CCAAACTCAA CTGACAAGTA TTACATTTAC 840
AATGGCTCAT TGACATCTCC TCCCTGCACA GACACAGTTG ACTGGATTGT TTTTAAAGAT 900
ACACTTAGCA TCTCTGAAAG CCAGTTGGCT GTTTTTTTGT GAAGTTCTTA CAATGCAACA 960
ATCTGGTTAT GTCATGCTGA TGGACTACTT ACAAAACAAT TTTCGAGAGC AACAGTACAA 1020
GTTCTCTAGA CAGGTGTTTT CCTCATACAC TGGAAAGGAA GAGATTCATG AAGCAGTTTG 1080
TAGTTCAGAA CCAGAAAATG TTCAGGCTGA CCCAGAGAAT TATACCAGCC TTCTTGTTAC 1140
ATGGGAAAGA CCTCβAGTCG TTTATGATAC CATGATTGAG AAGTTTβCAβ TTTTGTACCA 1200
GCAGTTGGAT GGAβAββACC AAACCAAβCA TGAATTTTTG ACAGATGGCT ATCAAGACTT 1260
GG6TGCTATT CTCAATAATT TGCTACCCAA TATGAGTTAT GTTCTTCAGA TAGTAGCCAT 1320
ATGCACTAAT GGCTTATATG GAAAATAGAG CGACCAACTG ATTGTCGACA TGCCTACTGA 1380
TAATCCT6AA CTTGATCTTT TCCCTGAATT AATTGGAACT GAAGAAATAA TCAAGGAGGA 1440
GGAAGAGββA AAAGACATTG AAGAAGGCGC TATTGTGAAT CCTGGTAGAG ACAGTGCTAC 1500
AAACCAAATC AGGAAAAAGG AACCCCAGAT TTCTACCACA ACACACTACA ATCGCATAGG 1560
GACGAAATAC AATGAAGCCA AGACTAACCG ATCCCCAACA AGAGGAAβTG AATTCTCTGG 1620
AAAGGGTGAT GTTCCCAATA CATCTTTAAA TTCCACTTCC CAACCAGTCA CTAAATTAGC 1680
CACAGAAAAA GATATTTCCT TGACTTCTCA GACTGTGACT GAACTβCCAC CTCACACTGT 1740
GGAAGGTACT TCAGCCTCTT TAAATGATβG CTCTAAAACT GTTCTTAGAT CTCCACATAT 1800
GAACTTGTCG GGGACTGCAG AATCCTTAAA TACAGTTTCT ATAACAGAAT ATGAGGAGGA 1860
GAGTTTATTG ACCAGTTTCA AGCTTGATAC TGGAGCTGAA GATTCTTCAβ GCTCCAGTCC 1920
CGCAACTTCT GCTATCCCAT TCATCTCTGA βAACATATCC CAAGGGTATA TATTTTCCTC 1980
CGAAAACCCA GAGACAATAA CATATGATGT CCTTATACCA GAATCTGCTA GAAATGCTTC 2040
CGAAGATTCA ACTTCATCAG GTTCAGAAGA ATCACTAAAG GATCCTTCTA TGGAGGGAAA 2100
TGTβTGGTTT CCTAGCTCTA CAGACATAAC AGCACAGCCC GATβTTβGAT CAGGCAGAGA 2160
GAGCTTTCTC CAGACTAATT ACACTGAGAT ACGTβTTGAT GAATCTGAGA AGACAACCAA 2220
GTCCTTTTCT GCAGGCCCAG TGATGTCACA GGGTCCCTCA GTTACAGATC TGGAAATGCC 2280
ACATTATTCT ACCTTTGCCT ACTTCCCAAC TGAGGTAACA CCTCATGCTT TTACCCCATC 2340
CTCCAGACAA CAGGATTTGG TCTCCACGGT CAACGTGGTA TACTCGCAGA CAACCCAACC 2400
GGTATACAAT GAGGCCAGTA ATAGTAGCCA TGAGTCTCGT ATTGGTCTAG CTGAGGGGTT 2460
GGAATCCGAβ AAGAAGGCAG TTATACCCCT TGTGATCGTG TCAβCCCTβA CTTTTATCTG 2520
TCTAGTGGTT CTTGTGGGTA TTCTCATCTA CTGGAGGAAA TGCTTCCAGA CTGCACACTT 2580
TTACTTAGAG GACAGTACAT CCCCTAGAGT TATATCCACA CCTCCAACAC CTATCTTTCC 2640
AATTTCAGAT GATGTCGGAG CAATTCCAAT AAAGCACTTT CCAAAGCATG TTGCAβATTT 2700
ACATGCAAGT AGTGβGTTTA CTGAAGAATT TGAGACACTG AAAGAGTTTT ACCAGGAAGT 2760
GCAGAβCTGT ACTGTTGACT TAGβTATTAC AGCAGACAGC TCCAACCACC CAGACAACAA 2820
GCACAAGAAT CGATACATAA ATATCGTTGC CTATGATCAT AGCAGGGTTA AGCTAGCACA 2880 eCTTGCTGAA AGGATGGCAA ACTGACTGAT TATATCAATG CCAATTATGT TGATGGCTAC 2940
AACAGACCAA AAGCTTATAT TGCTGCCCAA GGCCCACTGA AATCCACAGC TGAAGATTTC 3000
TGGAGAATGA TATGGβAACA TAATβTGGAA GTTATTGTCA TGATAACAAA CCTCGTGGAβ 3060
AAAGGAAGGA GAAAATGTGA TCAGTACTGG CCTGCCGATG GGAGTGAGGA GTACGGGAAC 3120
TTTCTGGTCA CTCAGAAGAG TGTGCAAGTG CTTGCCTATT ATACTGTGAG GAATTTTACT 3180
CTAAGAAACA CAAAAATAAA AAAGGGCTCC CAGAAAGGAA GACCCAGTGβ ACGTGTGGTC 3240
ACACAGTATC ACTACACGCA GTGGCCTβAC ATGGGAGTAC CAGAGTACTC CCTGCCAGTG 3300
CTGACCTTTβ TGAGAAA6GC AGCCTATGCC AAGCGCCATG CAGTβGGGCC TGTTGTCGTC 3360
CACTGCAGTG CTGβAGTTGG AAGAACAGβC ACATATATTβ TGCTAGACAG TATGTTGCAG 3420
CAGATTCAAC ACGAAGGAAC TGTCAACATA TTTGGCTTCT TAAAACACAT CCGTTCACAA 3480
AGAAATTATT TGGTACAAAC TGAGβAβCAA TATGTCTTCA TTCATGATAC ACTGβTTβAG 3540 GCCATACTTA GTAAAGAAAC TGAGβTGCTG GACAGTCATA TTCATGCCTA TGTTAATGCA '3600
CTCCTCATTC CTGGACCAGC AGβCAAAACA AAGCTAGAGA AACAATTCCA GGβTCTCACT 3660
CTGTCACCCA GGCTGGAGTG CACAβGCACA ATCTC6GCTC ACTGCAACCT TCCTCTCCCT 3720
GGCTTAACTG ATCCTCCTAC CTCAGCCTCC CGAGTGβCTG GGACTATACT CCTGAGCCAG 3780
TCAAATATAC AGCAGAGTGA CTATTCTGCA GCCCTAAAGC AATGCAACAG GGAAAAβAAT 3840
CGAACTTCTT CTATCATCCC TGTGβAAAGA TCAAGGGTTG GCATTTCATC CCTGAGTGGA 3900
GAAGGCACAG ACTACATCAA TGCCTCCTAT ATCATGGGCT ATTACCAGAG CAATGAATTC 3960
ATCATTACCC AGCACCCTCT CCTTCATACC ATCAAG6ATT TCTGGAGGAT GATATGGGAC 4020
CATAATGCCC AACTGGTGGT TATGATTCCT GATGGCCAAA ACATGGCAGA AGATGAATTT 4080
GTTTACTGGC CAAATAAAGA TGAGCCTATA AATTGTGAGA GCTTTAAGGT CACTCTTATG 4140
GCTGAAGAAC ACAAATGTCT ATCTAATGAG GAAAAACTTA TAATTCAGGA CTTTATCTTA 4200
GAAGCTACAC AGGATGATTA TGTACTTGAA GTGAGGCACT TTCAGTGTCC TAAATGβCCA 4260
AATCCAGATA GCCCCATTAG TAAAACTTTT GAACTTATAA GTβTTATAAA AGAAβAAβCT 4320
GCCAATACββ ATGGGCCTAT GATTGTTCAT GATGAGCATβ GAGβAGTGAC GGCAGGAACT 4380
TTCTGTGCTC TGACAACCCT TATGCACCAA CTAGAAAAAG AAAATTCCGT GGATGTTTAC 4440
CAGGTAGCCA AGATGATCAA TCTGATGAGG CCAGGAGTCT TTGCTGACAT TGAGCAGTAT 4500
CAGTTTCTCT ACAAAGTGAT CCTCAGCCTT GTGGGCACAA GGCAGGAA6A GAATCCATCC 4560
ACCTCTCTGG ACAGTAATGG TGCAGCATTG CCTGATGβAA ATATAGCTGA GAGCTTAGAβ 4620
TCTTTAGTTT AACACAGAAA GGGGTGGGGG βACTCACATC TGAGCATTGT TTTCCTCTTC 4680
CTAAAATTAG GCAGGAAAAT CAGTCTAGTT CTGTTATCTG TTGATTTCCC ATCACCTGAC 4740
AGTAACTTTC ATβACATAGG ATTCTGCCGC CAAATTTATA TCATTAACAA TGTGTGCCTT 4800
TTTGCAAGAC TTGTAATTTA CTTATTATGT TTGAACTAAA ATGATTGAAT TTTACAGTAT 4860
TTCTAAGAAT GGAATTGTGG TATTTTTTTC TGTATTGATT TTAACAGAAA ATTTCAATTT 4920
ATAGAGGTTA GGAATTCCAA ACTACAGAAA ATGTTTGTTT TTAGTGTCAA ATTTTTAGCT 4980
GTATTTGTAG CAATTATCAG GTTT6CTAGA AATATAACTT TTAATACAGT AGCCTGTAAA 5040
TAAAACACTC TTCCATATGA TATTCAACAT TTTACAACTG CAGTATTCAC CTAAAGTAGA 5100
AATAATCTGT TACTTATTGT AAATACTGCC CTAGTGTCTC CATGGACCAA ATTTATATTT 5160
ATAATTGTAG ATTTTTATAT TTTACTACTG AGTCAAGTTT TCTAGTTCTG TGTAATTGTT 5220
TAGTTTAATG ACGTAGTTCA TTAGCTGGTC TTACTCTACC AGTTTTCTGA CATTGTATTG 5280
TGTTACCTAA GTCATTAACT TTGTTTCAGC ATGTAATTTT AACTTTTGTG GAAAATAGAA 5340
ATACCTTCAT TTTGAAAGAA GTTTTTATGA GAATAACACC TTACCAAACA TTGTTCAAAT 5400
GGTTTTTATC CAAGGAATTG CAAAAATAAA TATAAATATT GCCATTAAAA AAAAAAAAAA 5460
AAAAAAAAAA AAAAAAAAAA A 5481
Seq ID NO: C101 DNA Sequence
Nucleic Acid Accession # : Eos sequence
Coding sequence: 1. .3340
60
Figure imgf001262_0001
120 ACAGGAGCAC TGAATCAAAA . AAATTGGGGA AAGAAATATC CAACATGTAA TAGCCCAAAA 180 CAATCTCCTA TCAATATTGA TGAAGATCTT ACACAAGTAA ATGTGAATCT TAAGAAACTT 240 AAATTTCAGG GTTGGGATAA AACATCATTG βAAAACACAT TCATTCATAA CACTGGGAAA 300 ACAGTGβAAA TTAATCTCAC TAATGACTAC CGTGTCAGCG GAGGAGTTTC AGAAATGGTG 360 TTTAAAβCAA GCAAGATAAC TTTTCACTGβ GGAAAATGCA ATATGTCATC TGATGGATCA 420 GAGCATAGTT TAGAAGGACA AAAATTTCCA CTTGAGATGC AAATCTACTG CTTTGATGCG 480 GACCGATTTT CAAGTTTTGA ββAAβCAGTC AAAGGAAAAG GGAAGTTAAG AGCTTTATCC 540 ATTTTGTTTG AGGTTGGGAC AGAAGAAAAT TTGGATTTCA AAGCGATTAT TGATGGAGTC 600 GAAAGTGTTA GTCGTTTTGG GAAGCAGGCT GCTTTAGATC CATTCATACT GTTGAACCTT 660 CTGCCAAACT CAACTGACAA GTATTACATT TACAATGGCT CATTGACATC TCCTCCCTGC 720 ACAGACACAG TTGACTGGAT TGTTTTTAAA GATACAGTTA GCATCTCTGA AAGCCAGTTG 780 GCTGTTTTTT GTGAAGTTCT TACAATGCAA CAATCTGGTT ATGTCATGCT GATGGACTAC 840 TTACAAAACA ATTTTCGAGA GCAACAβTAC AAGTTCTCTA GACAGGTGTT TTCCTCATAC 900 ACTGGAAAGG AAGAGATTCA TGAAGCAGTT TGTAGTTCAG AACCAGAAAA TβTTCAGGCT 960 GACCCAGAGA ATTATACCAG CCTTCTTGTT ACATGGGAAA GACCTCGAGT CGTTTATGAT 1020 ACCATGATTG AβAAGTTTGC AGTTTTβTAC CAGCAGTTGG ATGGAGAGGA CCAAACCAAG 1080 CATGAATTTT TGACAGATGG CTATCAAGAC TTGGGTGCTA TTCTCAATAA TTTGCTACCC 1140 AATATGAGTT ATGTTCTTCA GATAGTAGCC ATATGCACTA ATGGCTTATA TGGAAAATAC 1200 AGCGACCAAC TGATTGTCGA CATGCCTACT GATAATGCTG AGGCCAGTAA TAGTAGCCAT 1260 GAGTCTCβTA TTGGTCTAGC TGAβGGGTTG GAATCCGAGA AGAAGGCAGT TATACCCCTT 1320 GTGATCGTGT CAGCCCTGAC TTTTATCTGT CTAGTGGTTC TTGTGGGTAT TCTCATCTAC 1380 TGGAGGAAAT GCTTCCAGAC TGCACACTTT TACTTAGAGG ACAGTACATC CCCTAGAGTT 1440 ATATCCACAC CTCCAACACC TATCTTTCCA ATTTCA6ATG ATGTCGGAGC AATTCCAATA 1500 AAGCACTTTC CAAAGCATGT TGCAGATTTA CATGCAAβTA GTGGGTTTAC TβAAGAATTT 1560 GAGACACTGA AAGAGTTTTA CCAGGAAGTG CAGAGCTGTA CTGTTGACTT AGGTATTACA 1620 GCAGACAGCT CCAACCACCC AGACAACAAG CACAAβAATC GATACATAAA TATCGTTGCC 1680 TATGATCATA GCAGGGTTAA GCTAβCACAG CTTGCTGAAA AGGATGGCAA ACTGACTGAT 1740 TATATCAATG CCAATTATGT TGATGGCTAC AACAGACCAA AAGCTTATAT TGCTGCCCAA 1800 GGCCCACTGA AATCCACAGC TGAAGATTTC TGGAGAATGA TATGGGAACA TAATGTGGAA 1860 GTTATTGTCA TGATAACAAA CCTCGTGGAG AAAGGAAGGA GAAAATβTGA TCAGTACTGG 1920 CCTGCCGATG GGAGTGAGGA GTACGGGAAC TTTCTGGTCA CTCAGAAGAG TGTGCAAGTG 1980 CTTGCCTATT ATACTGTGAG GAATTTTACT CTAAGAAACA CAAAAATAAA AAAGGGCTCC 2040 CAGAAAGGAA GACCCAGTGG ACGTGTGGTC ACACAGTATC ACTACACβCA GTGβCCTGAC 2100 ATGβGAGTAC CAGAGTACTC CCTGCCAGTG CTGACCTTTβ TGAGAAAGGC AGCCTATβCC 2160 AAGCGCCATG CAGTGGβGCC TGTTGTCGTC CACTβCAβTG CTGGAβTTβe AAGAACAGGC 2220 ACATATATTG TGCTAGACAG TATGTTGCAG CAGATTCAAC ACβAAGGAAC TGTCAACATA 2280 TTTGGCTTCT TAAAACACAT CCGTTCACAA AGAAATTATT TGGTACAAAC TGAGGAGCAA 2340 TATGTCTTCA TTCATGATAC ACTGGTTGAG GCCATACTTA GTAAAGAAAC TGAGGTGCTG 2400 GACAGTCATA TTCATGCCTA . TGTTAATGCA CTCCTCATTC CTGGACCAGC AGGCAAAACA 2460 AAGCTAGAGA AACAATTCCA . GCTCCTGAGC CAGTCAAATA TACAGCAGAG TGACTATTCT 2520 GCAGCCCTAA AGCAATGCAA . CAGGGAAAAG AATCGAACTT CTTCTATCAT CCCTGTGGAA 2580 AGATCAAGGG TTGGCATTTC I ATCCCTGAGT GGAGAAGGCA CAGACTACAT CAATGCCTCC 2640 TATATCATGG GCTATTACCA GAGCAATGAA TTCATCATTA CTCAGCACCC TGTCCTTCAT 2700
ACCATCAAGG ATTTCTβGAG GATGATATGG GACCATAATG CCCAACTGGT GGTTATGATT 2760
CCTGATGGCC AAAACATGGC AGAAGATGAA TTTGTTTACT GGCCAAATAA AGATGAGCCT 2820
ATAAATTGTG AGAGCTTTAA GGTCACTCTT ATGGCTGAAG AACACAAATG TCTATCTAAT 2880
GAGGAAAAAC TTATAATTCA GGACTTTATC TTAGAAGCTA CACAGGATGA TTATGTACTT 2940
GAAGTGAGGC ACTTTCAGTG TCCTAAATGG CCAAATCCAG ATAGCCCCAT TAGTAAAACT 3000
TTTGAACTTA TAAGTGTTAT AAAAGAAGAA GCTGCCAATA GGGATGGGCC TATβATTβTT 3060
CATGATGAGC ATGβAββAGT GACGβCAβGA ACTTTCTGTG CTCTGACAAC CCTTATβCAC 3120
CAACTAGAAA AAGAAAATTC CGTGGATGTT TACCAGGTAG CCAAGATGAT CAATCTGATG 3180
10 AGGCCAGGAG TCTTTGCTGA CATTGAGCAG TATCAGTTTC TCTACAAAβT GATCCTCAGC 3240
CTTGTGAGCA CAAGGCAGGA AGAGAATCCA TCTACCTCTC TGGACAGTAA TGGTGCAGCA 3300
TTGCCTGATG GAAATATAGC TGAGAGCTTA GAGTCTTTAG 3340
Λ Seq ID NO: CIO 2 DNA Sequence lj Nucleic Acid Accession ft : Eos sequence
Coding sequence : 1. .4480
1 11 21 31 41 51
I I I I I I
20 ATGCGAATCC TAAAGCGTTT CCTCGCTTGC ATTCAGCTCC TCTGTGTTTG CCGCCTGGAT 60
TGGGCTAATG GATACTACAG ACAACAGAGA AAACTTCTTG AAGAGATTGG CTGGTCCTAT 120
ACAGGAGCAC TGAATCAAAA AAATTGGGGA AAGAAATATC CAACATGTAA TAGCCCAAAA 180
CAATCTCCTA TCAATATTGA TGAAGATCTT ACACAAGTAA ATGTGAATCT TAAGAAACTT 240
AAATTTCAGG GTTGGGATAA AACATCATTG GAAAACACAT TCATTCATAA CACTGGGAAA 300
25 ACAGTGGAAA TTAATCTCAC TAATGACTAC CGTGTCAGCG GAGGAGTTTC AGAAATGGTG 360
TTTAAAGCAA GCAAGATAAC TTTTCACTGG GGAAAATGCA ATATGTCATC TGATGGATCA 420
GAGCATAGTT TAGAAβGACA AAAATTTCCA CTTGAGATGC AAATCTACTG CTTTGATGCA 480
GACCGATTTT CAAGTTTTGA GGAAGCAGTC AAAGGAAAAG GGAAGTTAAG AGCTTTATCC 540
ATTTTGTTTβ AGGTTGGGAC AGAAGAAAAT TTGGATTTCA AAGCGATTAT TGATGGAGTC 600
30 GAAAGTGTTA GTCGTTTTGG GAAGCAGGCT GCTTTAGATC CATTCATACT GTTGAACCTT 660
CTGCCAAACT CAACTGACAA GTATTACATT TACAATGGTT CATTGACATC TCCTCCCTGC 720
ACAGACACAG TTGACTββAT TGTTTTTAAA βATACAβTTA GCATCTCTGA AAGCCAGTTG 780
GCTGTTTTTT GTGAAGTTCT TACAATGCAA CAATCTGGTT ATGTCATGCT GATGGACTAC 840
TTACAAAACA ATTTTCGAGA GCAACAGTAC AAGTTCTCTA GACAGGTGTT TTCCTCATAC 900
35 ACTGGAAAGG AAGAGATTCA TGAAGCAGTT TGTAGTTCAG AACCAGAAAA TGTTCAGGCT 960
GACCCAGAGA ATTATACCAG CCTTCTTGTT ACATGGGAAA GACCTCGAGT CGTTTATGAT 1020
ACCATGATTG AGAAGTTTβC AGTTTTGTAC CAGCAGTTGG ATGGAGAGGA CCAAACCAAG 1080
CATGAATTTT TGACAGATGG CTATCAAGAC TTGGGTGCTA TTCTCAATAA TTTGCTACCC 1140
AATATGAGTT ATGTTCTTCA GATAGTAGCC ATATGCACTA ATGGCTTATA TGGAAAATAC 1200
40 AGCGACCAAC TGATTGTCGA CATβCCTACT βATAATCCTG AACTTGATCT TTTCCCTGAA 1260
TTAATTGGAA CTGAAβAAAT AATCAAGGAG GAGGAAGAGG GAAAAGACAT TGAAGAAGGC 1320
GCTATTGTGA ATCCTGGTAG AGACAGTGCT ACAAACCAAA TCAGGAAAAA GGAACCCCAG 1380
ATTTCTACCA CAACACACTA CAATCGCATA GGGACGAAAT ACAATGAAGC CAAGACTAAC 1440
CGATCCCCAA CAAGAGGAAG TGAATTCTCT GGAAAGGGTG ATGTTCCCAA TACATCTTTA 1500
45 AATTCCACTT CCCAACCAGT CACTAAATTA GCCACAGAAA AAGATATTTC CTT6ACTTCT 1560
CAGACTGTGA CTGAACTGCC ACCTCACACT GTGGAAGGTA CTTCAGCCTC TTTAAATGAT 1620
GβCTCTAAAA CTGTTCTTAG ATCTCCACAT ATβAACTTGT CGGGGACTGC AGAATCCTTA 1680
AATACAGTTT CTATAACAGA ATATGAGGAG GAGAGTTTAT TGACCAGTTT CAAGCTTGAT 1740
ACTGGAGCTG AAGATTCTTC AGGCTCCAGT CCCGCAACTT CTGCTATCCC ATTCATCTCT 1800
50 GAGAACATAT CCCAAGGGTA TATATTTTCC TCCGAAAACC CAGAGACAAT AACATATGAT 1860
GTCCTTATAC CAGAATCTGC TAGAAATGCT TCCGAAGATT CAACTTCATC AGGTTCAGAA 1920
GAATCACTAA AGGATCCTTC TATGGAGGGA AATGTGTβGT TTCCTAGCTC TACAGACATA 1980
ACAGCACAGC CCGATGTTGG ATCAGGCAGA GAGAGCTTTC TCCAGACTAA TTACACTGAG 2040
ATACGTβTTG ATGAATCTGA GAAGACAACC AAGTCCTTTT CTGCAGGCCC AGTGATβTCA 2100
55 CAGGGTCCCT CAGTTACAβA TCTGGAAATG CCACATTATT CTACCTTTGC CTACTTCCCA 2160
ACTGAGGTAA CACCTCATβC TTTTATCCCA TCCTCCAβAC AACAGGATTT GGTCTCCACG 2220
GTCAACGTGG TATACTCGCA GACAACCCAA CCGGTATACA ATGAGGCCAG TAATAGTAGC 2280
CATGAGTCTC GTATTGGTCT AGCTGAGGGG TTGGAATCCG AGAAGAAGGC AβTTATACCC 2340
CTTGTGATCG TβTCAβCCCT GACTTTTATC TGTCTAGTGG TTCTTGTGGG TATTCTCATC 2400
60 TACTGβAβGA AATGCTTCCA βACTGCACAC TTTTACTTAG AGGACAβTAC ATCCCCTAGA 2460
GTTATATCCA CACCTCCAAC ACCTATCTTT CCAATTTCAG ATGATGTCGG AGCAATTCCA 2520 ATAAAGCACT TTCCAAAGCA TGTTGCAGAT TTACATGCAA GTAGTGGGTT TACTGAAGAA 2580 TTTGAGACAC TGAAAGAGTT TTACCAGGAA GTGCAGAGCT GTACTGTTGA CTTAGGTATT 2640 ACAGCAGACA GCTCCAACCA CCCAGACAAC AAGCACAAGA ATCGATACAT AAATATCGTT 2700
65 GCCCATGATC ATAGCAGGGT TAAGCTAGCA CAGCTTGCTG AAAAGGATGG CAAACTGACT 2760 GATTATATCA ATGCCAATTA TβTTGATGGC TACAACAGAC CAAAAGCTTA TATTGCTβCC 2820 CAAβGCCCAC TGAAATCCAC AGCTGAAβAT TTCTGGAGAA TGATATGGGA ACATAATGTG 2880 GAAGTTATTG TCATGATAAC AAACCTCGTG GAGAAAGGAA GGAGAAAATG TGATCAGTAC 2940 TGGCCTGCCG ATGGGAGTGA GGAGTACGGG AACTTTCTGG TCACTCAGAA GAGTGTGCAA 3000
70 GTGCTTGCCT ATTATACTGT GAGGAATTTT ACTCTAAGAA ACACAAAAAT AAAAAAGGGC 3060 TCCCAGAAAG GAAGACCCAG TGGACGTGTG GTCACACACT ATCACTACAC βCAGTGGCCT 3120 GACATGGGAG TACCAGAGTA CTCCCTGCCA GTGCTGACCT TTβTGAGAAA GβCAGCCTAT 3180 GCCAAβCGCC ATGCAGTGGG GCCTGTTGTC GTCCACTGCA GTGCTGGAGT TGGAAGAACA 3240 GGCACATATA TTGTGCTAGA CAβTATGTTG CAGCAGATTC AACACGAAGG AACTGTCAAC 3300
75 ATATTTGGCT TCTTAAAACA CATCCGTTCA CAAAGAAATT ATTTGGTACA AACTGAGGAG 3360 CAATATGTCT TCATTCATGA TACACTGGTT GAGGCCATAC TTAGTAAAGA AACTGAGGTG 3420 CTGGACAGTC ATATTCATGC CTATGTTAAT βCACTCCTCA TTCCTGGACC AGCAGGCAAA 3480 ACAAAGCTAG AGAAACAATT CCAGGGTCTC ACTCTGTCAC CCAGGCTGGA GTGCAGAGGC 3540 ACAATCTCGG CTCACTGCAA CCTTCCTCTC CCTGGCTTAA CTCATCCTCC TACCTCAGCC 3600
80 TCCCGAGTGG CTAGGACTAT ACTCCTGAGC CAGTCAAATA TACAGCAGAG TGACTATTCT 3660 GCAGCCCTAA AGCAATGCAA CAGGGAAAAG AATCGAACTT CTTCTATCAT CCCTGTGGAA 3720 AGATCAAGGG TTGGCATTTC ATCCCTGAGT GGAGAAGGCA CAGACTACAT CAATGCCTCC 3780 TATATCATGG GCTATTACCA GAGCAATGAA TTCATCATTA CCCAGCACCC TCTCCTTCAT 3840 ACCATCAAGG ATTTCTGGAG GATGATATGG GACCATAATG CCCAACTGGT GGTTATGATT 3900 CCTGATGGCC AAAACATGGC AGAAGATGAA TTTGTTTACT GGCCAAATAA AGATGAGCCT 3960
ATAAATTGTG AGAGCTTTAA GGTCACTCTT ATGGCTGAAG AACACAAATG TCTATCTAAT 4020
GAGGAAAAAC TTATAATTCA GGACTTTATC TTAGAAGCTA CACAGβATGA TTATGTACTT 4080
GAAGTGAGGC ACTTTCAGTG TCCTAAATGG CCAAATCCAG ATAGCCCCAT TACTAAAACT 4140
TTTGAACTTA TAAGTGTTAT AAAAGAAGAA GCTGCCAATA GGGATGGGCC TATGATTGTT 4200
CATGATGAGC ATGGAGGAGT GACGGCAGGA ACTTTCTGTG CTCTGACAAC CCTTATGCAC 4260
CAACTAGAAA AAGAAAATTC CGTGGATGTT TACCAGGTAG CCAAGATGAT CAATCTGATG 4320
AGGCCAGGAG TCTTTGCTGA CATTGAGCAG TATCAGTTTC TCTACAAAGT GATCCTCAGC 4380
CTTGTGAGCA CAAGGCAGGA AGAGAATCCA TCCACCTCTC TGGACAGTAA TGGTGCAGCA 4440
TTGCCTGATG GAAATATAGC TGAGAGCTTA GAGTCTTTAG 4480
Seq ID NO: CIO3 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 1..4220
1 11 21 31 41 51
I I I I I I
ATGCGAATCC TAAAGCGTTT CCTCGCTTGC ATTCAGCTCC TCTGTGTTTG CCGCCTGGAT 60
TGGGCTAATG GATACTACAG ACAACAGAGA AAACTTGTTG AAGAGATTGG CTGβTCCTAT 120
ACAGGAGCAC TGAATCAAAA AAATTGGGGA AAGAAATATC CAACATGTAA TAGCCCAAAA 180
CAATCTCCTA TCAATATTGA TGAAGATCTT ACACAAGTAA ATGTGAATCT TAAGAAACTT 240
AAATTTCAGG GTTGGGATAA AACATCATTG GAAAACACAT TCATTCATAA CACTGGGAAA 300
ACAGTGGAAA TTAATCTCAC TAATGACTAC CGTGTCAGCG GAGGAGTTTC AGAAATGGTG 360
TTTAAAGCAA GCAAGATAAC TTTTCACTGG GGAAAATGCA ATATGTCATC TGATGGATCA 420
GAGCATAGTT TAGAAGβACA AAAATTTCCA CTTGAGATGC AAATCTACTG CTTTGATGCC 480
GACCGATTTT CAAGTTTTGA GGAAGCAGTC AAAGGAAAAG GGAAGTTAAG AGCTTTATCC 540
ATTTTGTTTG AGGTTGGGAC AGAAGAAAAT TTGGATTTCA AAGCGATTAT TGATGGAGTC 600
GAAAGTGTTA GTCGTTTTGG GAAGCAGGCT GCTTTAGATC CATTCATACT GTTGAACCTT 660
CTGCCAAACT CAACTGACAA GTATTACATT TACAATGβCT CATTGACATC TCCTCCCTGC 720
ACAGACACAG TTGACTGGAT TGTTTTTAAA GATACAGTTA GCATCTCTGA AAGCCAGTTG 780
GCTGTTTTTT GTGAAGTTCT TACAATGCAA CAATCTGGTT ATGTCATGCT GATGGACTAC 840
TTACAAAAGA ATTTTCGAGA GCAACAGTAC AAGTTCTCTA GACAGGTGTT TTCCTCATAC 900
ACTGGAAAGG AAGAGATTCA TGAAGCAGTT TGTAGTTCAG AACCAGAAAA TGTTCAGGCT 960
GACCCAGAGA ATTATACCAG CCTTCTTGTT ACATGβGAAA GACCTCGAGT CGTTTATGAT 1020
ACCATGATTG AGAAGTTTGC AGTTTTGTAC CAGCAGTTGG ATGGAGAGGA CCAAACCAAβ 1080
CATGAATTTT TGACAGATGG CTATCAAGAC TTGGGTGCTA TTCTCAATAA TTTGCTACCC 1140
AATATGAGTT ATGTTCTTCA GATAGTAGCC ATATGCACTA ATGGCTTATA TGGAAAATAC 1200
AGCGACCAAC TGATTGTCGA CATGCCTACT GATAATCCTG AACTTGATCT TTTCCCTGAA 1260
TTAATTGGAA CTGAAGAAAT AATCAAGGAβ GAGGAAGAGG GAAAAGACAT TGAAGAAGGC 1320
GCTATTGTGA ATCCTGβTAG AGACAGTGCT ACAAACCAAA TCAGGAAAAA GGAACCCCAG 1380
ATTTCTACCA CAACACACTA CAATCGCATA GGGACGAAAT ACAATGAAGC CAAGACTAAC 1440
CGATCCCCAA CAAGAGGAAG TGAATTCTCT GGAAAGGGTG ATGTTCCCAA TACATCTTTA 1500
AATTCCACTT CCCAACCAGT CACTAAATTA GCCACAGAAA AAGATATTTC CTTGACTTCT 1560
CAGACTGTGA CTGAACTGCC ACCTCACACT GTGGAAGGTA CTTCAGCCTC TTTAAATGAT 1620
GGCTCTAAAA CTGTTCTTAG ATCTCCACAT ATGAACTTGT CGGββACTGC AGAATCCTTA 1680
AATACAGTTT CTATAACAGA ATATGAGGAG GAGAGTTTAT TGACCAGTTT CAAGCTTGAT 1740
ACTGGAGCTG AAGATTCTTC AGGCTCCAGT CCCGCAACTT CTGCTATCCC ATTCATCTCT 1800
GAGAACATAT CCCAAGGGTA TATATTTTCC TCCGAAAACC CAGAGACAAT AACATATGAT 1860
GTCCTTATAC CAGAATCTGC TAGAAATGCT TCCGAAGATT CAACTTCATC AGGTTCAGAA 1920
GAATCACTAA AGGATCCTTC TATGGAGGGA AATGTGTGGT TTCCTAGCTC TACAGACATA 1980
ACAGCACAGC CCGATGTTGG ATCAGGCAGA GAGAGCTTTC TCCAGACTAA TTACACTGAG 2040
ATACGTGTTG ATGAATCTGA GAAGACAACC AAGTCCTTTT CTGCAGβCCC AβTGATGTCA 2100
CAGGGTCCCT CAGTTACAGA TCTGGAAATG CCACATTATT CTACCTTTGC CTACTTCCCA 2160
ACTGAGβTAA CACCTCATβC TTTTACCCCA TCCTCCAGAC AACAGGATTT GβTCTCCACβ 2220 βTCAACβTGG TATACTCGCA GACAACCCAA CCGGTATACA ATGAGGCCAG TAATAGTAGC 2280
CATGAGTCTC GTATTGGTCT AGCTGAGGβG TTGGAATCCG AGAAGAAGGC AGTTATACCC 2340
CTTGTGATCG TGTCAGCCCT GACTTTTATC TGTCTAGTGG TTCTTGTGGG TATTCTCATC 2400
TACTGβAGGA AATGCTTCCA GACTGCACAC TTTTACTTAG AGGACAGTAC ATCCCCTAGA 2460 βTTATATCCA CACCTCCAAC ACCTATCTTT CCAATTTCAG ATGATGTCGG AGCAATTCCA 2520
ATAAAGCACT TTCCAAAGCA TGTTGCAGAT TTACATGCAA GTAGTGGGTT TACTGAAGAA 2580
TTTGAGACAC TGAAAGAGTT TTACCAGGAA GTGCAGAGCT GTACTGTTGA CTTAGGTATT 2640
ACAGCAGACA βCTCCAACCA CCCAGACAAC AAGCACAAGA ATCGATACAT AAATATCGTT 2700
GCCTATGATC ATAGCAGGGT TAAGCTAGCA CAGCTTGCTG AAAAGGATGG CAAACTGACT 2760
GATTATATCA ATGCCAATTA TGTTGATGβC TACAACAGAC CAAAAGCTTA TATTGCTGCC 2820
CAAGβCCCAC TβAAATCCAC AGCTGAAGAT TTCTGGAGAA TGATATGGGA ACATAATGTG 2880
GAAGTTATTG TCATGATAAC AAACCTCGTG GAGAAAGGAA GGAGAAAATG TGATCAGTAC 2940
TGGCCTGCCG ATGGGAGTβA GGAGTACGGG AACTTTCTGG TCACTCAGAA GAβTβTGCAA 3000
GTGCTTGCCT ATTATACTGT GAGGAATTTT ACTCTAAGAA ACACAAAAAT AAAAAAGGGC 3060
TCCCAGAAAG 6AAGACCCAG TGGACβTGTG GTCACACAGT ATCACTACAC GCAGTGGCCT 3120
GACATGGGAG TACCAGAGTA CTCCCTGCCA GTGCTGACCT TTGTGAGAAA GGCAGCCTAT 3180
GCCAAβCβCC ATGCAGTGGG GCCTGTTGTC GTCCACTGCA GTβCTGGAGT TGGAAGAACA 3240 βGCACATATA TTGTGCTAGA CAGTATGTTG CAGCAGATTC AACACGAAGβ AACTGTCAAC 3300
ATATTTGGCT TCTTAAAACA CATCCGTTCA CAAAGAAATT ATTTGGTACA AACTGAGβAG 3360
CAATATGTCT TCATTCATGA TACACTGGTT GAGGCCATAC TTAGTAAAGA AACTGAGGTG 3420
CTGGACA6TC ATATTCATGC CTATGTTAAT GCACTCCTCA TTCCTGGACC AGCAGGCAAA 3480
ACAAAGCTAG AGAAACAATT CCAGCTCCTG AGCCAGTCAA ATATACAGCA GAGTGACTAT 3540
TCTGCAGCCC TAAAGCAATG CAACAGGGAA AAGAATCGAA CTTCTTCTAT CATCCCTGTG 3600
GAAAGATCAA GGGTTGGCAT TTCATCCCTG AGTGGAGAAβ GCACAGACTA CATCAATGCC 3660
TCCTATATCA TGGGCTATTA CCAGAGCAAT GAATTCATCA TTACCCAGCA CCCTCTCCTT 3720
CATACCATCA AGGATTTCTG GAGGATGATA TGGGACCATA ATGCCCAACT GβTβGTTATG 3780
ATTCCTGATG GCCAAAACAT GGCAGAAGAT GAATTTGTTT ACTGGCCAAA TAAAGATGAG 3840
CCTATAAATT GTGAGAGCTT TAAGGTCACT CTTATGGCTG AAGAACACAA ATGTCTATCT 3900
AATGAGβAAA AACTTATAAT TCAGGACTTT ATCTTAGAAG CTACACAGGC ATGGAGGAGT 3960
GACGGCAβGA ACTTTCTGTG CTCTGACAAC CCTTATGCAC CAACTAGAAA AAGAAAATTC 4020 CGTGGATGTT TACCAGGTAG CCAAGATGAT CAATCTGATG AGGCCAGGAG TCTTTGCTGA 4080
CATTGAGCAG TATCAGTTTC TCTACAAAGT GATCCTCAGC CTTGTβAβCA CAAGGCAGGA 4140
AGAGAATCCA TCCACCTCTC TGGACAGTAA TGGTGCAGCA TTGCCTGATG GAAATATAGC 4200
TGAGAGCTTA GAGTCTTTAG 4220
Seq ID NO : C104 DNA Sequence
Nucleic Acid Accession # : XM.002914 . 6
Coding sequence : 1 . .4314
11 21 31 41 51
I I I I I I
ATGAAGGATA TCGACATAGG AAAAGAGTAT ATCATCCCCA GTCCTGGGTA TAGAAGTGTG 60
AGGGAβAGAA CCAGCACTTC TGGGACGCAC AGAGACCGTG AAGATTCCAA GTTCAGGAGA 120
ACTCGACCGT TGGAATGCCA AGATGCCTTG GAAACAGCAG CCCGAGCCGA GGGCCTCTCT 180
CTTGATGCCT CCATGCATTC TCAGCTCAβA ATCCTGGATG AGGAGCATCC CAAGGGAAAG 240
TACCATCATG GCTTGAGTGC TCTGAAβCCC ATCCGGACTA CTTCCAAACA CCAGCACCCA 300
GTGGACAATG CTGβGCTTTT TTCCTGTATG ACTTTTTCGT GGCTTTCTTC TCTGGCCCGT 360
GTGGCCCACA AGAAGGGGGA GCTCTCAATG GAAβACGTGT GGTCTCTGTC CAAGCACGAG 420
TCTTCTβACG TGAACTGCAG AAGACTAGAG AGACTGTGGC AAGAAGAGCT GAATGAAGTT 480
GGGCCAGACG CTGCTTCCCT GCβAAβGGTT GTGTGGATCT TCTGCCGCAC CAGGCTCATC 540
CTGTCCATCG TGTGCCTGAT GATCACGCAG CTGGCTGGCT TCAGTGGACC AGCCTTCATG 600
GTGAAACACC TCTTGGAGTA TACCCAGGCA ACAGAGTCTA ACCTGCAGTA CAGCTTGTTG 660
TTAGTGCTGG GCCTCCTCCT GACGGAAATC GTGCCβTCTT GGTCGCTTGC ACTGACTTCβ 720 βCATTGAATT ACCGAACCGG TGTCCGCTTG CGGβββGCCA TCCTAACCAT GGCATTTAAG 780
AAGATCCTTA AGTTAAAGAA CATTAAAGAG AAATCCCTGG GTGAGCTCAT CAACATTTGC 840
TCCAACGATG GGCAGAGAAT GTTTGAGGCA GCAGCCGTTG GCAGCCTGCT GGCTGGAGGA 900
CCCGTTGTTG CCATCTTAGG CATGATTTAT AATGTAATTA TTCTGGGACC AACAGGCTTC 960
CTGGGATCAG CTGTTTTTAT CCTCTTTTAC CCAGCAATGA TGTTTGCATC ACGGCTCACA 1020
GCATATTTCA GGAGAAAATG CGTGGCCGCC ACGGATGAAC GTGTCCAGAA GATGAATGAA 1080
GTTCTTACTT ACATTAAATT TATCAAAATG TATGCCTGβG TCAAAGCATT TTCTCAβAGT 1140
GTTCAAAAAA TCCGCGAGGA GGAGCGTCGG ATATTGGAAA AAGCTGGGTA CTTCCAβAGC 1200
ATCACTGTGG GTGTGGCTCC CATTGTGGTG GTGATTGCCA GCGTGGTGAC CTTCTCTGTT 1260
CATATGACCC TGGGCTTCGA TCTGACAGCA GCACAGGCTT TCACAGTβGT GACAGTCTTC 1320
AATTCCATGA CTTTTGCTTT GAAAGTAACA CCGTTTTCAG TAAAGTCCCT CTCAGAAGCC 1380
TCAGTGGCTG TTGACAGATT TAAGAGTTTG TTTCTAATGG AAGAGGTTCA CATGATAAAG 1440
AACAAACCAG CCAGTCCTCA CATCAAGATA GAGATGAAAA ATGCCACCTT GGCATGGβAC 1500
TCCTCCCACT CCAGTATCCA GAACTCGCCC AAGCTGACCC CCAAAATGAA AAAAGACAAG 1560
AGGGCTTCCA GGGGCAAGAA AGA6AAGGTG AGGCAGCTβC AGCGCACTGA GCATCAGGCG 1620
GTGCTGGCAG AGCAGAAAGβ CCACCTCCTC CTGGACAGTG ACGAGCGβCC CAGTCCCGAA 1680
GAGGAAGAAG GCAAGCACAT CCACCTGGGC CACCTGCGCT TACAGAGβAC ACTGCACAGC 1740
ATCGATCTGG AGATCCAAGA GββTAAACTG GTTGGAATCT GCGGCAGTβT GGGAAGTGGA 1800
AAAACCTCTC TCATTTCAGC CATTTTAGGC CAGATGACGC TTCTAGAGGG CAGCATTGCA 1860
ATCAGTGGAA CCTTCGCTTA TGTGGCCCAG CAGGCCTGβA TCCTCAATβC TACTCTGAGA 1920
GACAACATCC TGTTTGGGAA GGAATATGAT GAAGAAAGAT ACAACTCT6T GCTGAACAGC 1980
TGCTGCCTGA GGCCTGACCT GGCCATTCTT CCCAGCAGCG ACCTGACβGA GATTGGAGAG 2040
CGAGGAGCCA ACCTGAGCGG TGGGCAGCβC CAGAββATCA GCCTTGCCCG GGCCTTGTAT 2100
AGTGACAGGA GCATCTACAT CCTGGACGAC CCCCTCAGTG CCTTAGATGC CCATGTGGGC 2160
AACCACATCT TCAATAGTGC TATCCGGAAA CATCTCAAGT CCAAGACAGT TCTGTTTGTT 2220
ACCCACCAGT TACAGTACCT GGTTGACTGT GATGAAGTβA TCTTCATGAA AGAGG6CTGT 2280
ATTACGβAAA GAGGCACCCA TGAGGAACTG ATGAATTTAA ATGGTGACTA TGCTACCATT 2340
TTTAATAACC TGTTGCTGGG AGAβACACCG CCAGTTGAGA TCAATTCAAA AAAGGAAACC 2400
AGTGGTTCAC AGAAGAAGTC ACAAGACAAG GGTCCTAAAA CAGGATCAGT AAAGAAGGAA 2460
AAAGCAGTAA AGCCAGAGGA AGGGCAGCTT βTβCAβCTGG AAGAAAAAGG GCAGGGTTCA 2520
GTGCCCTGGT CAGTATATGG TGTCTACATC CAGGCTGCTG GGGGCCCCTT GGCATTCCTβ 2580
GTTATTATGG CCCTTTTCAT GCTGAATGTA GGCAGCACCG CCTTCAGCAC CTGβTGGTTG 2640
AGTTACTGGA TCAAGCAAGG AAGCGGGAAC ACCACTGTβA CTCGAGGGAA CGAGACCTCG 2700
GTGAGTGACA GCATGAAGGA CAATCCTCAT ATGCAGTACT ATGCCAGCAT CTACCCCCTC 2760
TCCATβGCAG TCATGCTGAT CCTGAAAGCC ATTCGAGβAG TTGTCTTTGT CAAGGGCACG 2820
CTGCGAGCTT CCTCCCGGCT GCATGACGAG CTTTTCCGAA GGATCCTTCG AAGCCCTATG 2880
AAGTTTTTTG ACACGACCCC CACAGGGAβG ATTCTCAACA GGTTTTCCAA AGACATGGAT 2940
GAAGTTGACG TGCGGCTGCC GTTCCAGGCC GAGATGTTCA TCCAGAACGT TATCCTGGTG 3000
TTCTTCTGTG TGGGAATGAT CGCAGGAGTC TTCCCGTGGT TCCTTGTGGC AGTGGGGCCC 3060
CTT6TCATCC TCTTTTCAGT CCTGCACATT GTCTCCAββG TCCTGATTCG GGAGCTGAAG 3120
CGTCTGβACA ATATCACGCA GTCACCTTTC CTCTCCCACA TCACGTCCAG CATACAGG6C 3180
CTTGCCACCA TCCACCCCTA CAATAAAGGG CAGGAGTTTC TGCACAGATA CCAGGAGCTG 3240
CTGGATGACA ACCAAGCTCC TTTTTTTTTG TTTACGTGTG CGATGCGGTG GCTGGCTGTG 3300
CGGCTGGACC TCATCAGCAT CGCCCTCATC ACCACCACGG 6GCTGATGAT CGTTCTTATβ 3360
CACGGGCAGA TTCCCCCAGC CTATGCGβGT CTCGCCATCT CTTATGCTGT CCAGTTAACβ 3420 ββGCTGTTCC AGTTTACGGT CAGACTGβCA TCTGAGACAG AAGCTCGATT CACCTCGGTG 3480
GAGAGGATCA ATCACTACAT TAAGACTCTG TCCTTGGAAG CACCTGCCAC AATTAAGAAC 3540
AAGGCTCCCT CCCCTGACTG GCCCCAGGAG GGAGAGGTβA CCTTTGAβAA CGCAGAGATG 3600 AGGTACCGAG AAAACCTCCC TCTCGTCCTA AAGAAAGTAT CCTTCACGAT CAAACCTAAA 3660 GAGAAGATTG GCATTGTGGG GCGGACAGGA TCAGGGAAGT CCTCGCTGGG GATGGCCCTC 3720 TTCCGTCTGG TGGAGTTATC TGGAGGCTGC ATCAAGATTG ATGGAGTGAG AATCAGTGAT 3780 ATTGGCCTTG CCGACCTCCG AAGCAAACTC TCTATCATTC CTCAAGAGCC GGTGCTGTTC 3840 AGTββCACTC TCAGATCAAA TTTGGACCCC TTCAACCAGT ACACTGAAGA CCAGATTTGG 3900 GATGCCCTGG AβAGGACACA CATGAAAGAA TGTATTGCTC AGCTACCTCT GAAACTTGAA 3960 TCTGAAGTGA TGGAGAATGG GGATAACTTC TCAGTGGGGG AACGGCAGCT CTTGTGCATA 4020 GCTACAGCCC TGCTCCGCCA CTGTAAGATT CTGATTTTAG ATGAAGCCAC AGCTGCCATG 4080 6ACACAGAGA CAGACTTATT GATTCAAGAG ACCATCCGAG AAGCATTTGC AGACTGTACC 4140 ATGCTGACCA TTGCCCATCG CCTGCACACG GTTCTAGGCT CCGATAGβAT TATβGTGCTβ 4200 GCCCAGGGAC AGGTGGTGGA GTTTGACACC CCATCGGTCC TTCTGTCCAA CGACAβTTCC 4260 CGATTCTATβ CCATGTTTGC TGCTβCAβAG AACAAGGTCG CTGTCAAGGG CTAG 4314 Seq ID NO: CIO5 DNA Sequence
Nucleic Acid Accession #: NM_005688.1
Coding sequence: 126..4439
1 11 21 31 41 51
I I I I I I
CCGGGCAGGT GGCTCATGCT CGGGAGCGTG GTTGAGCGGC TGGCGCGGTT GTCCTGGAβC 60
AGGGGCGCAG GAATTCTGAT GTGAAACTAA CAGTCTGTGA GCCCTGGAAC CTCCGCTCAG 120
AGAAGATGAA GGATATCGAC ATAGGAAAAG AGTATATCAT CCCCAGTCCT GGGTATAGAA 180
GTβTGAGGGA GAGAACCAGC ACTTCTGGGA CGCACAGAGA CCGTGAAGAT TCCAAGTTCA 240
GGAβAACTCβ ACCβTTGGAA TGCCAAGATG CCTTGGAAAC AGCAGCCCGA GCCGAGGGCC 300
TCTCTCTTGA TGCCTCCATG CATTCTCAGC TCAGAATCCT GGATGAGGAG CATCCCAAGG 360
GAAAGTACCA TCATGGCTTG AGTGCTCTGA AGCCCATCCG GACTACTTCC AAACACCAGC 420
ACCCAβTβGA CAATGCTGGG CTTTTTTCCT GTATGACTTT TTCGTGGCTT TCTTCTCTGG 480
CCCGTGTGGC CCACAAGAAβ GGGGAGCTCT CAATCβAAGA CGTβTGGTCT CTGTCCAAGC 540
ACβAGTCTTC TGACGTGAAC TGCAGAAGAC TAGAGAGACT GTGGCAAGAA GAGCT6AATG 600
AAGTTGGGCC AGACGCTGCT TCCCTGCCAA GGGTTGTGTG GATCTTCTGC CGCACCAGGC 660
TCATCCTGTC CATCGTGTGC CTGATGATCA CGCAGCTGGC TGGCTTCAGT GGACCAGCCT 720
TCATGGTGAA ACACCTCTTG GAGTATACCC AGβCAACAGA GTCTAACCTG CAGTACAGCT 780
TGTTGTTAGT GCTGGGCCTC CTCCTGACGG AAATCGTGCG GTCTTGGTCG CTTGCACTGA 840
CTTβGGCATT βAATTACCGA ACCGGTGTCC GCTTGCGGGG GGCCATCCTA ACCATGGCAT 900
TTAAGAAGAT CCTTAAGTTA AAGAACATTA AAGAGAAATC CCTGGGTGAG CTCATCAACA 960
TTTGCTCCAA CGATGβGCAG AGAATGTTTG AGβCAGCAGC CGTTGGCAGC CTGCTGGCTG 1020
GAGGACCCGT TGTTGCCATC TTAGGCATGA TTTATAATGT AATTATTCTG βGACCAACAG 1080
GCTTCCTGGG ATCAGCTGTT TTTATCCTCT TTTACCCAGC AATGATGTTT GCATCACGGC 1140
TCACAGCATA TTTCAGGAGA AAATGCGTGG CCGCCACGGA TGAACGTGTC CAGAAGATGA 1200
ATGAAGTTCT TACTTACATT AAATTTATCA AAATGTATGC CTGGGTCAAA GCATTTTCTC 1260
AGAGTGTTCA AAAAATCCβC GAGGAGGAGC GTCGβATATT GGAAAAAGCC GGGTACTTCC 1320
AβββTATCAC TGTGGGTGTG GCTCCCATTG TGGTGGTGAT TGCCAGCGTG GTGACCTTCT 1380
CTGTTCATAT GACCCTGGGC TTCGATCTGA CAGCAGCACA GGCTTTCACA GTGGTGACAG 1440
TCTTCAATTC CATβACTTTT GCTTTGAAAG TAACACCGTT TTCAGTAAAG TCCCTCTCAG 1500
AAGCCTCAGT GGCTGTTGAC AGATTTAAGA GTTTGTTTCT AATβGAAGAG GTTCACATGA 1560
TAAAGAACAA ACCAGCCAGT CCTCACATCA AGATAGAGAT GAAAAATGCC ACCTTGGCAT 1620
GGGACTCCTC CCACTCCAGT ATCCAGAACT CGCCCAAGCT GACCCCCAAA ATGAAAAAAG 1680
ACAAGAGGGC TTCCAGGGGC AAGAAAGAGA AGGTGAGGCA GCTGCAGCβC ACTGAGCATC 1740
AGGCGGTGCT GGCAGAGCAG AAAGGCCACC TCCTCCTGGA CAGTGACβAG CGGCCCAGTC 1800
CCGAAGAGGA AGAAGGCAAG CACATCCACC TGGGCCACCT GCGCTTACAG AGGACACTGC 1860
ACAGCATCGA TCTβGAGATC CAAGAGGGTA AACTGGTTGG AATCTGCGGC AGTGTGGGAA 1920
GTGGAAAAAC CTCTCTCATT TCAGCCATTT TAGGCCAGAT GACGCTTCTA GAGGGCAGCA 1980
TTGCAATCAG TGGAACCTTC GCTTATGTGβ CCCAGCAGGC CTGGATCCTC AATGCTACTC 2040
TGAGAGACAA CATCCTGTTT G6GAAGGAAT ATGATGAAGA AAGATACAAC TCTGTGCTGA 2100
ACAGCTGCTG CCTGAGGCCT GACCTGGCCA TTCTTCCCAG CAGCGACCTG ACGGAGATTβ 2160
GAGAGCGAGG AGCCAACCTG AβCGGTGGGC AGCGCCAGAG GATCAGCCTT GCCCGββCCT 2220
TGTATAGTGA CAGGAGCATC TACATCCTGG ACGACCCCCT CAGTGCCTTA GATGCCCATG 2280
TGGGCAACCA CATCTTCAAT AGTGCTATCC GGAAACATCT CAAGTCCAAG ACAGTTCTGT 2340
TTGTTACCCA CCAGTTACAG TACCTGGTTG ACTGTGATGA AGTGATCTTC ATGAAAGAGG 2400
GCTGTATTAC GGAAAGAGGC ACCCATGAGG AACTGATGAA TTTAAATββT GACTATGCTA 2460
CCATTTTTAA TAACCTGTTG CTGGGAGAGA CACCGCCAGT TGAGATCAAT TCAAAAAAGG 2520
AAACCAGTGG TTCACAGAAG AAGTCACAAG ACAAGGGTCC TAAAACAGGA TCAGTAAAGA 2580
AββAAAAAGC AGTAAAGCCA GAGGAAGGGC AGCTTGTGCA GCTGGAAGAG AAAGGGCAGG 2640
GTTCAGTGCC CTGGTCAGTA TATGGTGTCT ACATCCAGGC TGCTGGGGGC CCCTTGGCAT 2700
TCCTGGTTAT TATGGCCCTT TTCATGCTGA ATGTAGGCAG CACCGCCTTC AGCACCTGGT 2760
GGTTGAGTTA CTGGATCAAG CAAGGAAGCG GGAACACCAC TGTGACTCGA GGGAACGAGA 2820
CCTCGGTGAβ T6ACAGCATG AAGGACAATC CTCATATGCA GTACTATGCC AGCATCTACG 2880
CCCTCTCCAT GGCAGTCATG CTGATCCTGA AAGCCATTCG AGGAGTTGTC TTTGTCAAGG 2940
GCACGCTGCG AGCTTCCTCC CGGCTGCATG ACGAGCTTTT CCGAAGGATC CTTCGAAGCC 3000
CTATGAAβTT TTTTGACACG ACCCCCACAG GGAGGATTCT CAACAGGTTT TCCAAAGACA 3060
TGGATβAAGT TGACGTGCGG CTGCCGTTCC AGGCCGAGAT GTTCATCCAG AACGTTATCC 3120
TGGTβTTCTT CTGTGTGGGA ATGATCGCAG GAGTCTTCCC GTGGTTCCTT GTGGCAGTGG 3180
GGCCCCTTGT CATCCTGTTT TCAGTCCTGC ACATTGTCTC CAGGGTCCTG ATTCGGGAGC 3240
TGAAGCGTCT GGACAATATC ACGCAGTCAC CTTTCCTCTC CCACATCACG TCCAGCATAC 3300
AGGGCCTTGC CACCATCCAC GCCTACAATA AAGGGCAGGA GTTTCTGCAC AGATACCAGG 3360
AGCTGCTGGA TGACAACCAA GCTCCTTTTT TTTTGTTTAC GTGTGCGATG CGGTGGCTGG 3420
CTGTGCGGCT GGACCTCATC AGCATCGCCC TCATCACCAC CACGGGGCTG ATGATCGTTC 3480
TTATGCACGG GCAGATTCCC CCAGCCTATG CGββTCTCGC CATCTCTTAT GCTGTCCAGT 3540
TAACGGGGCT GTTCCAGTTT ACGGTCAGAC TGGCATCTGA GACAGAAGCT CGATTCACCT 3600
CGGTGGAGAG GATCAATCAC TACATTAAGA CTCTGTCCTT GβAAGCACCT GCCAGAATTA 3660
AGAACAAGGC TCCCTCCCCT GACTGGCCCC AGGAGGGAGA GGTGACCTTT GAGAACGCAG 3720
AGATGAββTA CCβAβAAAAC CTCCCTCTTG TCCTAAAGAA AGTATCCTTC ACGATCAAAC 3780
CTAAAGAGAA GATTGGCATT GTGGGGCGGA CAGGATCAGG GAAGTCCTCG CTGGGGATGG 3840
CCCTCTTCCG TCTGβTGGAG TTATCTGGAG GCTGCATCAA GATTGATGGA GTGAGAATCA 3900
GTGATATTGG CCTTGCCGAC CTCCGAAGCA AACTCTCTAT CATTCCTCAA GAGCCGGTGC 3960
TGTTCAGTGG CACTβTCAGA TCAAATTTGG ACCCCTTCAA CCAGTACACT GAAGACCAGA 4020
TTTGGGATGC CCTGGAGAGG ACACACATGA AAGAATGTAT TGCTCAGCTA CCTCTGAAAC 4080
TTGAATCTGA AGTGATGGAG AATGGβGATA ACTTCTCAGT GGGGGAACGG CAGCTCTTGT 4140
GCATAGCTAG AGCCCTGCTC CGCCACTGTA AGATTCTGAT TTTAGATGAA GCCACAGCTG 4200
CCATGGACAC AGAGACAGAC TTATTGATTC AAβAGACCAT CCGAβAAGCA TTTGCACACT 4260
GTACCATGCT GACCATTGCC CATCGCCTGC ACACGGTTCT AGGCTCCGAT AGGATTATGG 4320
TGCTGGCCCA GGGACAGGTG GTGGAGTTTG ACACCCCATC GGTCCTTCTG TCCAACGACA 4380
GTTCCCGATT CTATGCCATG TTTGCTGCTG CAGAGAACAA GGTCGCTGTC AAGGGCTGAC 4440
TCCTCCCTGT TGACGAAGTC TCTTTTCTTT AGAGCATTGC CATTCCCTGC CTGGGβCβGG 4500
CCCCTCATCG CGTCCTCCTA CCGAAACCTT GCCTTTCTCG ATTTTATCTT TCGCACAGCA 4560
GTTCCGGATT GGCTTGTGTG TTTCACTTTT AGGGAGAGTC ATATTTTGAT TATTβTATTT 4620
ATTCCATATT CATGTAAACA AAATTTAGTT TTTGTTCTTA ATTGCACTCT AAAAGGTTCA 4680 GGGAACCGTT ATTATAATTG TATCAGAGGC CTATAATGAA GCTTTATACG TGTAGCTATA 4740
TCTATATATA ATTCTGTACA TAGCCTATAT TTACAGTGAA AATGTAAGCT GTTTATTTTA 4800
TATTAAAATA AGCACTGTGC TAATAACAGT βCATATTCCT TTCTATCATT TTTGTACAGT 4860
TTGCTGTACT AGAGATCTGG TTTTGCTATT AGACTGTAGG AAGAGTAGCA TTTCATTCTT 4920
CTCTAGCTGG TGGTTTCACG GTGCCAGGTT TTCTGGGTGT CCAAAGGAAG ACGTβTβGCA 4980
ATAGTGββCC CTCCβACAGC CCCCTCTGCC GCCTCCCCAC AGCCGCTCCA GβββTGβCTG 5040
GAGACCGGTG GGCGGCTGGA GACCATGCAβ AβCβCCGTβA βTTCTCAGGG CTCCTGCCTT 5100
CT6TCCTGGT GTCACTTACT GTTTCTGTCA GGAGAGCAGC GGGGCGAAGC CCAGGCCCCT 5160
TTTCACTCCC TCCATCAAGA ATGβGGATCA CAGAGACATT CCTCCGAGCC GGGGAGTTTC 5220
TTTCCTGCCT TCTTCTTTTT GCTGTTGTTT CTAAACAAGA ATCAGTCTAT CCACAGAGAG 5280
TCCCACTGCC TCAGGTTCCT ATGGCTGGCC ACTGCACAGA GCTCTCCAGC TCCAAGACCT 5340
GTTGGTTCCA AGCCCTGGAG CCAACTGCTG CTTTTTGAGG TGGCACTTTT TCATTTGCCT 5400
ATTCCCACAC CTCCACAGTT CAGTGGCAGG GCTCAGGATT TCGTGGGTCT GTTTTCCTTT 5460
CTCACCGCAG TCGTCGCACA CTCTCTCTCT CTCTCTCCCC TCAAAβTCTG CAACTTTAAG 5520
CAGCTCTTGC TAATCAGTGT CTCACACTGG CGTAGAAGTT TTTGTACTGT AAAGAGACCT 5580
ACCTCAGGTT GCTβGTTGCT GTGTGGTTTG GTGTGTTCCC GCAAACCCCC TTTGTGCTGT 5640
GGGGCTGGTA GCTCAGGTGG βCGTGGTCAC TGCTGTCATC AGTTGAATGG TCAGCGTTGC 5700
ATGTCGTGAC CAACTAGACA TTCTGTCGCC TTAGCATGTT TGCTGAACAC CTTGTGGAAG 5760
CAAAAATCTG AAAATGTGAA TAAAATTATT TTGGATTTTG TAAAAAAAAA AAAAAAAAAA 5820
AAAAAAAAAA AAAAAAAA 5838
Seq ID NO: CIO6 DNA Sequence Nucleic Acid Accession ft: NM_005562 Coding sequence: 90..3671
1 11 21 31 41 51
I I I I I I
ACAGCGGAGC GCAGAGTGAG AACCACCAAC CGAGGCGCCG GGCAGCGACC CCTGCAGCGG 60
AGACAGAGAC TGAGCGGCCC GGCACCGCCA TGCCTGCGCT CTGGCTGGGC TβCTβCCTCT 120 βCTTCTCGCT CCTCCTGCCC GCAGCCCβGG CCACCTCCAG GAGGGAAβTC TβTβATTGCA 180
ATGGGAAGTC CAGGCAGTGT ATCTTTGATC GGGAACTTCA CAGACAAACT GGTAATGGAT 240
TCCGCTβCCT CAACTGCAAT GACAACACTβ ATGGCATTCA CTGCGAGAAG TGCAAβAATβ 300
GCTTTTACCG GCACAGAGAA AGGGACCGCT βTTTGCCCTG CAATTGTAAC TCCAAAGGTT 360
CTCTTAGTGC TCGATGTGAC AACTCTGGAC GGTβCAGCTG TAAACCAGGT GTGACAGGAG 420
CCAGATGCGA CCGATGTCTG CCAGGCTTCC ACATGCTCAC GGATGCGGGG TGCACCCAAβ 480
ACCAGAGACT GCTAGACTCC AAGTGTGACT βTGACCCAGC TGGCATCGCA GGβCCCTGTG 540
ACβCGGGCCG CTGTGTCTGC AAGCCAGCTG TTACTGGAGA ACGCTGTGAT AGGTGTCGAT 600
CACβTTACTA TAATCTGGAT GGGGGGAACC CTGAGGGCTG TACCCAGTGT TTCTGCTATG 660 ββCATTCAGC CAGCTGCCGC AGCTCTGCAβ AATACAβTGT CCATAAGATC ACCTCTACCT 720
TTCATCAAGA TGTTGATGGC TGGAAGGCTG TCCAACGAAA TGGGTCTCCT GCAAAGCTCC 780
AATGGTCACA GCGCCATCAA GATGTGTTTA GCTCAGCCCA ACGACTAGAC CCTGTCTATT 840
TTGTGGCTCC TGCCAAATTT CTTGGGAATC AACAGGTGAG CTATGβGCAA AβCCTβTCCT 900
TTβACTACCβ TGTGGACAGA GGAGGCAGAC ACCCATCTβC CCATGATGTG ATTCTGGAAG 960
GTβCTGGTCT ACGGATCACA GCTCCCTTGA TGCCACTTGβ CAAGACACTG CCTTβTβGβC 1020
TCACCAAGAC TTACACATTC AGGTTAAATG AGCATCCAAG CAATAATTGG AGCCCCCAGC 1080
TGAGTTACTT TGAGTATCGA AGGTTACTGC GGAATCTCAC AGCCCTCCGC ATCCGAGCTA 1140
CATATGGAGA ATACAGTACT GGGTACATTG ACAATGTGAC CCTGATTTCA GCCCβCCCTG 1200
TCTCTGGAGC CCCAGCACCC TGGGTTGAAC AGTGTATATβ TCCTβTTGGβ TACAAβGGGC 1260
AATTCTGCCA GGATTGTGCT TCTGGCTACA AGAGAGATTC AGCGAGACTG GββCCTTTTG 1320
GCACCTGTAT TCCTTGTAAC TGTCAAGGGG GAGGGGCCTβ TGATCCAGAC ACAGGAGATT 1380
GTTATTCAGG GGATGAGAAT CCTGACATTG AGTGTGCTGA CTGCCCAATT GGTTTCTACA 1440
ACGATCCGCA CGACCCCCGC AβCTGCAAGC CATGTCCCTG TCATAACGGG TTCAGCTGCT 1500
CAGTβATβCC GGAGACGGAG GAGGTGGTGT GCAATAACTG CCCTCCCGGG GTCACCGGTG 1560
CCCGCTβTGA GCTCTGTGCT GATGGCTACT TTGβ∞ACCC CTTTGGTGAA CATGGCCCAG 1620
TGAβGCCTTG TCAGCCCTGT CAATGCAACA ACAATGTG6A CCCCAGTGCC TCT6GGAATT 1680
GTGACCGβCT GACAGGCAGG TGTTTβAAβT GTATCCACAA CACAGCCGGC ATCTACTGCG 1740
ACCAGTGCAA AGCAGGCTAC TTCGGGGACC CATTGGCTCC CAACCCA6CA GACAAGTGTC 1800
GAβCTTβCAA CTβTAACCCC ATGGβCTCAβ AβCCTGTAGβ ATGTCGAAGT GATββCACCT 1860
GTGTTTGCAA GCCAGGATTT GβTGGCCCCA ACTGTGAβCA TGGAGCATTC AGCTGTCCAG 1920
CTTGCTATAA TCAAGTβAAG ATTCAGATGG ATCAGTTTAT GCAGCAGCTT CAGAGAATGG 1980
AGGCCCTGAT TTCAAAGGCT CAGGGTGGTG ATGGAGTAGT ACCTGATACA GAGCTGGAAG 2040
GCAGGATGCA GCAGGCTGAG CAGGCCCTTC AGβACATTCT βAGAGATGCC CAGATTTCAG 2100
AAGβTGCTAG CAGATCCCTT GGTCTCCAGT TGβCCAAGGT 6AGGAGCCAA GAGAACAβCT 2160
ACCAGAGCCG CCTGβATGAC CTCAAGATGA CTGTGGAAAG AGTTCGGGCT CTGGGAAGTC 2220
AGTACCAGAA CCGAβTTCGG 6ATACTCACA GGCTCATCAC TCAGATGCAG CTGAGCCTGG 2280
CAGAAAGTGA AGCTTCCTTG GGAAACACTA ACATTCCTGC CTCAGACCAC TACGTGGGGC 2340
CAAATGGCTT TAAAAGTCTG GCTCAGGAGG CCACAAGATT AGCAGAAAGC CACGTTGAGT 2400
CAGCCAGTAA CATGGAGCAA CTGACAAGGG AAACTGAGGA CTATTCCAAA CAAGCCCTCT 2460
CACTGGTGCG CAAGGCCCTG CATGAAGGAG TCGGAAGCGG AAGCGGTAGC CCGGACGGTG 2520
CTGTGGTβCA AGGGCTTGTG GAAAAATTGG AGAAAACCAA GTCCCTGGCC CAβCAGTTGA 2580
CAAGGGAGβC CACTCAAGCG GAAATTGAAG CAβATAGGTC TTATCAβCAC AβTCTCCGCC 2640
TCCTGβATTC AGTGTCTCGG CTTCAGGGAG TCAGTGATCA CTCCTTTCAG GTββAAβAAG 2700
CAAAGAββAT CAAACAAAAA GCGGATTCAC TCTCAACGCT GGTAACCAGG CATATGGATG 2760
ACTTCAAβCβ TACACAAAAG AATCTGGGAA ACTGGAAAGA AGAAGCACAG CAGCTCTTAC 2820
AGAATGGAAA AAGTGGGAGA GAGAAATCAG ATCAGCTGCT TTCCCGTGCC AATCTTGCTA 2880
AAAGCAGAGC ACAAβAAβCA CTGAGTATGG GCAATGCCAC TTTTTATGAA GTTGAGA8CA 2940
TCCTTAAAAA CCTCAGAGAG TTTGACCTGC AGGTGGACAA CAGAAAAGCA GAAGCTGAAG 3000
AACCCATGAA GAGACTCTCC TACATCAGCC AβAAGGTTTC AGATβCCAGT GACAAGACCC 3060
AGCAAGGAGA AAGAGCCCTG GGGAGCGCTG CTGCTGATGC ACAGAGβGCA AAGAATGGGG 3120
CCGGGGAGGC CCTGGAAATC TCCAGTGAβA TTGAACAGGA GATTGGGAGT CTGAACTTGG 3180
AAGCCAATGT GACAGCAGAT GβAGCCTTGG CCATGGAAAA GGβACTGGCC TCTCTGAAGA 3240
GTGAGATGAG GGAAGTGGAA GGAGAGCTGG AAAGGAAGGA GCTGGAGTTT GACACGAATA 3300
TGGATGCAGT ACAGATGGTG ATTACAGAAG CCCAGAAGGT TGATACCAGA GCCAACAACG 3360 CTGGGGTTAC AATCCAAGAC ACACTCAACA CATTAGACGG CCTCCTGCAT CTGATGGACC 3420 AGCCTCTCAG TGTAGATGAA GAGGGGCTGG TCTTACTGGA GCAGAAGCTT TCCCGAGCCA 3480
AGACCCAGAT CAACAGCCAA CTGCGGCCCA TGATGTCAGA GCTGGAAGAG AGGGCACGTC 3540
AGCAGAGGGG CCACCTCCAT TTGCTGGAGA CAAGCATAGA TGGGATTCTG GCTGATGTGA 3600
AGAACTTGGA GAACATTAGG GACAACCTGC CCCCAGGCTG CTACAATACC CAGGCTCTTG 3660
AGCAACAGTG AAGCTGCCAT AAATATTTCT CAACTGAGGT TCTTGGGATA CAGATCTCAG 3720
GGCTCGGGAG CCATGTCATG TGAGTGGGTG GGATGGGGAC ATTTGAACAT GTTTAATGββ 3780
TATGCTCAβG TCAACTGACC TGACCCCATT CCTGATCCCA TGGCCAGGTG βTTGTCTTAT 3840
TGCACCATAC TCCTTGCTTC CTGATβCTGG GCAATGAββC AGATAGCACT GGGTGTGAGA 3900
ATGATCAAGG ATCTGGACCC CAAAGAATAG ACTCGATGGA AAGACAAACT GCACAGGCAG 3960
ATGTTTGCCT CATAATAβTC GTAAβTGGAG TCCTGGAATT TGGACAAGTG CTGTTGGGAT 4020
ATAGTCAACT TATTCTTTGA GTAATGTGAC TAAAGGAAAA AACTTTGACT TTGCCCAGβC 4080
ATGAAATTCT TCCTAATGTC AGAACAGAβT GCAACCCAGT CACACTGTGG CCAGTAAAAT 4140
ACTATTGCCT CATATTGTCC TCTGCAAGGT TCTTGCTβAT CAGAGTTCCT CCTACTTACA 4200
ACCCAGGGTG TGAACATGTT CTCCATTTTC AAGCTGGAAG AAGTGAGCAG TGTTGGAGTG 4260
AGGACCTGTA AGGCAGGCCC ATTCAGAβCT ATGGTGCTTG CTGGTGCCTG CCACCTTCAA 4320
GTTCTCβACC TGGGCATGAC ATCCTTTCTT TTAATGATβC CATGGCAACT TAGAGATTGC 4380
ATTTTTATTA AAGCATTTCC TACCAGCAAA βCAAATβTTG GGAAAGTATT TACTTTTTCβ 4440
GTTTCAAAGT GATAGAAAAG TGTGGCTTGG GCATTGAAAG AGβTAAAATT CTCTAGATTT 4500
ATTAGTCCTA ATTCAATCCT ACTTTTCGAA CACCAAAAAT GATGCGCATC AATGTATTTT 4560
ATCTTATTTT CTCAATCTCC TCTCTCTTTC CTCCACCCAT AATAAGAGAA TGTTCCTACT 4620
CACACTTCAG CTGGGTCACA TCCATCCCTC CATTCATCCT TCCATCCATC TTTCCATCCA 4680
TTACCTCCAT CCATCCTTCC AACATATATT TATTGAGTAC CTACTGTGTG CCAGGGβCTβ 4740
GTGGGACAGT GGTGACATAG TCTCTGCCCT CATAGAGTTG ATTGTCTAGT GAGGAAGACA 4800
AGCATTTTTA AAAAATAAAT TTAAACTTAC AAACTTTGTT TGTCACAAβT GGTGTTTATT 4860
GCAATAACCG CTTGGTTTGC AACCTCTTTG CTCAACAGAA CATATGTTGC AAGACCCTCC 4920
CATGβGGGCA CTTGAGTTTT ββCAAβGCTG ACAGAGCTCT GGGTTGTGCA CATTTCTTTG 4980
CATTCCAGCT GTCACTCTGT GCCTTTCTAC AACTGATTGC AACAGACTGT TGAGTTATGA 5040
TAACACCAGT GGGAATTGCT GGAGGAACCA GAGGCACTTC CACCTTGGCT GGGAAGACTA 5100
TCβTGCTGCC TTGCTTCTGT ATTTCCTTGG ATTTTCCTGA AAGTβTTTTT AAATAAAGAA 5160
CAATTGTTAG ATGCC 5175
Seq ID NO CIO7 DNA Sequence Nucleic Acid Accession ft NM_021101 Coding sequence 221 856
1 11 21 31 41 51 1 1 | 1 I 1 | 1 | 1 I 1
GAATTCGGCA CGAGGCCTCG TGCCGGβGAG CAACCTCAGC TTCTAGTATC CAGACTCCAG 60
CGCCGCCCCG GGCGCGGACC CCAACCCCGA CCCAGAGCTT CTCCAGCGGC GβCGCAGCGA 120
GCAGGGCTCC CCGCCTTAAC TTCCTCCGCG GGGCCCAβCC ACCTTCGβGA GTCCGGGTTG 180
CCCACCTGCA AACTCTCCGC CTTCTGCACC TGCCACCCCT GAGCCAGCGC GGGCGCCCGA 240
GCGAβTCATG GCCAACGCβG GGCTGCAGCT GTTGGGCTTC ATTCTCGCCT TCCTGGGATG 300
GATCGGCGCC ATCGTCAGCA CTGCCCTGCC CCAGTGGAGG ATTTACTCCT ATGCCGGCGA 360
CAACATCGTG ACCGCCCAGG CCATGTACGA GGGGCTGTGG ATGTCCTGCG TGTCGCAGAG 420
CACCGGGCAG ATCCAGTGCA AAGTCTTTGA CTCCTTGCTG AATCTGAGCA GCACATTGCA 480
AGCAACCCGT GCCTTGATGG TGGTTGGCAT CCTCCTGGGA GTGATAGCAA TCTTTGTGGC 540
CACCGTTGGC ATGAAGTGTA TGAAGTGCTT GGAAGACGAT GAββTβCAGA AGATGAGGAT 600
GGCTGTCATT GGGGGCGCGA TATTTCTTCT TGCAGGTCTG GCTATTTTAG TTGCCACAGC 660
ATGGTATGGC AATAGAATCG TTCAAGAATT CTATGACCCT ATGACCCCAG TCAATGCCAG 720
GTACGAATTT GGTCAGGCTC TCTTCACTGG CTGGGCTGCT GCTTCTCTCT GCCTTCTGGG 780
AGGTGCCCTA CTTTGCTGTT CCTGTCCCCβ AAAAACAACC TCTTACCCAA CACCAAGGCC 840
CTATCCAAAA CCTGCACCTT CCAGCGGGAA AGACTACGTG TGACACAGAG GCAAAAGβAG 900
AAAATCATβT TGAAACAAAC CGAAAATGGA CATTβAβATA CTATCATTAA CATTAGGACC 960
TTAGAATTTT GGGTATTGTA ATCTAAAGTA TGTTATTACA AAACAAACAA ACAAACAAAA 1020
AACCCATGTG TTAAAATACT CAGTGCTAAA CATGGCTTAA TCTTATTTTA TCTTCTTTCC 1080
TCAATATAGG AGGGAAGATT TTTCCATTTG TATTACTGCT TCCCATTGAG TAATCATACT 1140
CAAATGGGGG AAGGGGTGCT CCTTAAATAT ATATAGATAT βTATATATAC ATGTTTTTCT 1200
ATTAAAAATA GCCAGTAAAA AAAAAAAAAA AAAAAAA 1237
Seq ID NO CIO8 DNA Sequence Nucleic Acid Accession # AF508964 1 Coding sequence 98 1531
1 11 21 31 41 51 1 1 | 1 | 1 | 1 1 I 1 CAGAGCCGCA AGCGCAGGGA AGGCCTCCCC GCACGGTGGG GGAAAGCGGC CGGTGCAGCG 60
CGGGGACAGG CACTCGβGCT GGCACTGGCT GCTAGGGATG TCGTCCTGGA TAAGCT6GCA 120
TGGACCCβCC ATGGCGCGGC TCTGGGGCTT CTGCTGGCTG GTTGTGGGCT TCTGGAβββC 180
CGCTTTCGCC TGTCCCACGT CCTGCAAATG CACTβCCTCT CGGATCTGGT GCAGCGACCC 240
TTCTCCTGGC ATCGTGβCAT TTCCGAGATT GGAGCCTAAC AGTGTAGATC CTGAGAACAT 300
CACCGAAATT TTCATCGCAA ACCAGAAAAG GTTAGAAATC ATCAACGAAG ATGATGTTGA 360
AGCTTATGTG GGACTGAGAA ATCTGACAAT TGTGGATTCT GGATTAAAAT TTGTGGCTCA 420
TAAAGCATTT CTGAAAAACA GCAACCTGCA GCACATCAAT TTTACCCGAA ACAAACTGAC 480
GAGTTTGTCT AβGAAACATT TCCGTCACCT TβACTTGTCT GAACTGATCC TGGTGGGCAA 540
TCCATTTACA TGCTCCTGTG ACATTATGTG GATCAAGACT CTCCAAGAGG CTAAATCCAG 600
TCCAGACACT CAβGATTTGT ACTGCCTGAA TGAAAGCAGC AAGAATATTC CCCTGGCAAA 660
CCTGCAGATA CCCAATTGTG GTTTGCCATC TGCAAATCTG GCCGCACCTA ACCTCACTGT 720
GGAGGAAGGA AAGTCTATCA CATTATCCTG TAGTGTGGCA GGTGATCCGG TTCCTAATAT 780
GTATTGGGAT GTTGGTAACC TGGTTTCCAA ACATATGAAT GAAACAAGCC ACACACAGGG 840
CTCCTTAAGG ATAACTAACA TTTCATCCGA TGACAβTGGG AAGCAGATCT CTTGTGTGGC 900
GGAAAATCTT GTAGGAGAAG ATCAAβATTC TGTCAACCTC ACTβTβCATT TTGCACCAAC 960
TATCACATTT CTCGAATCTC CAACCTCAGA CCACCACTGG TGCATTCCAT TCACTGTGAA 1020
AGGCAACCCC AAACCAGCGC TTCAGTGGTT CTATAACGGG GCAATATTGA ATGAGTCCAA 1080
ATACATCTGT ACTAAAATAC ATGTTACCAA TCACACGGAG TACCACGGCT GCCTCCAGCT 1140 GGATAATCCC ACTCACATGA ACAATGGGGA CTACACTCTA ATAGCCAAGA ATβAGTATGG 1200
GAAββATGAG AAACAGATTT CTGCTCACTT CATGGGCTGG CCTGGAATTG ACGATGGTGC 1260
AAACCCAAAT TATCCTGATG TAATTTATGA AGATTATGGA ACTGCAGCGA ATGACATCGG 1320
GGACACCACG AACAGAAGTA ATGAAATCCC TTCCACAGAC GTCACTGATA AAACCGGTCG 1380
GGAACATCTC TCGGTCTATG CTβTGGTGGT GATTGCGTCT GTGGTGGGAT TTTGCCTTTT 1440
GGTAATGCTG TTTCTGCTTA AGTTGGCAAG ACACTCCAAG TTTGGCATGA AAGGTTTTGT 1500
TTTGTTTCAT AAGATCCCAC TGGATGGGTA GCTGAAATAA AGGAAAAGAC AGAGAAAGGG 1560
GCTGTGGTGC TTGTTGGTTG ATβCTβCCAT GTAAGCTGGA CTCCTGGGAC TGCTGTTGGC 1620
TTATCCCGGG AAGTGCTGCT TATCTGGGGT TTTCTGGTAG ATGTGββCGG TGTTTGGAGG 1680
CTCTACTATA TGAAGCCTGC ATATACTGTG AGCTGTGATT GGGGAACACC AATGCAGAGG 1740
TAACTCTCAG βCAGCTAAGC AGCACCTCAA GAAAACATGT TAAATTAATG CTTCTCTTCT 1800
TACAβTAGTT CAAATACAAA ACTGAAATGA AATCCCATTG GATTGTACTT CTCTTCTGAA 1860
AAGTGTGCTT TTTGACCCTA CTGGACATTT ATTGACTTAA TTGCTTCTGT TTATTAAAAT 1920
TGACCTGCAA AGTTAAAAAA AAATTAAAGT TGAGAACAGG TATAAGTGCA CACTGAATAG 1980
TCTAATCTAC ATGTAACACA TATTTTAGTA TGATTTTCTA TACTCTAATC AGCACTGAAT 2040
TCAGAGGGTT TGACTTTTTC ATCTATAACA CAGTGACTAA AAGAGTTAAG GGTATATATA 2100
CCATCACTTT GGGACTTGGT AGTATTATTA AAAGGTTATT TCCTTCACTG TCAATAAAAG 2160
TCCAAATGTT TAGCTTAGGT CTGAGAGTCA AACAATGTTA AGGATTGTCT TAAAGTTCCT 2220
TAGCCAGCAA AACAAAACAA AACAAAACAA ACAAATGAAA AACGTTTAAA AAGAAGAAGA 2280
AGAAAAAAAA CAAGAACAAG CAGCAACAGC TGTTTTGTTG GGGCTATAGA TTTAAβTTAG 2340
GCATACTCAA TTTCAGAATA ACTAAGAGTG GAATATATGC ATATGGTGAA ATTATAACCT 2400
TGCCCTTTTT TATTTGCCCT CTGCGATCCA CCTGGCTTTT TAGAAGTCTG CCGAGTGAGA 2460
AGGCCACAGT ATCTCATGCT GTTTGCATTA CAGAACTGCA GCTTTTCTAC TCTGAAAAGG 2520
CCTGGGAGCA GAATGβCTβG CCTGCTGTβA GCAGGAGAGG AGATTCTAAβ AAββATAβTC 2580
CCCCCTACAA CATACTGTCA TACTGCTGGG TTTTCATGββ TAGGAAAGCT TGTCCTGACC 2640
CCAGCAGCAA AGAβGTGGCA GGTCβCTAAT GAATATATGC TTTATAATGT CCTTCTTCAT 2700
TGCTGAGAGG GCAGCCTTAG AGCTGTGGAT TTCTGCATCC CCCCTGAGTC TGACCCATGG 2760
ACACCTGTTT CATTCACTTT AGCATCACAG TβACCTTTGT ATGCTCTGTT CAGTCTGTGT 2820
CAGGCAGTAT GCTTGTCCTG AAGAGAβGTT TGGCTATCCC CCACCCCACC CACCCACCCT 2880
GTTCCTTTTT TATCAGGAGG ACTTCAGAGC CAGGCCTGCA GCATTTTGTT TGAAAACACA 2940
ATCACCTCTG ACAGTTAβAC ATCCACACAG ACGCCATAGC TGGATTGGAA ACATTGATGT 3000
TTTAAAAATT TATTTTTTTT GGAAATAGTT GCACAAATGC TGCAATTTAG CTTTAAGGTT 3060
CTATAGATTT TTAACTAGTC CAACACAGTC AGAAACATTG TTTTGAATCC TCTGTAAACC 3120
AAGGCATTAA TCTTAATAAA CCAGGATCCA TTTAGGTACC ACTTGATATA AAAAGGATAT 3180
CCATAATGAA TATTTTATAC TGCATCCTTT ACATTAGCCA CTAAATACGT TATTGCTTGA 3240
TGAAGACCTT TCACAGAATC CTATGGATTG CAGCATTTCA CTTGGCTACT TCATACCCAT 3300
GCCTTAAAGA GβGGCAGTTT CTCAAAAGCA GAAACATGCC GCCAGTTCTC AAGTTTTCCT 3360
CCTAACTCCA TTTGAATGTA AGGGCAGCTG GCCCCCAATG TGGGGAGGTC CGAACATTTT 3420
CTGAATTCCC ATTTTCTTGT TCGCβGCTAA ATGACAGTTT CTGTCATTAC TTAGATTCCβ 3480
ATCTTTCCCA AAββTGTTGA TTTACAAAGA GGCCAGCTAA TAGCAGAAAT CATGACCCTC 3540
AAAGAβAGAT GAAATTCAAG CTGTβAβCCA GGCAGGAGCT CAGTATGGCA AAGGTTCTTG 3600
AGAATCAGCC ATTTGGTACA AAAAAGATTT TTAAAGCTTT TATGTTATAC CATGβAGCCA 3660
TAGAAAGGCT ATGβATTGTT TAAGAACTAT TTTAAAGTGT TCCAGACCCA AAAAGGAAAA 3720
ATAAAAAAAA AβGAATATTT GTACCCAACA GCTAGAAGGA TTGCAAGGTA GATTTTTGTT 3780
TTAAAATGGA GAGAAGTββA CAGATAAGGC CATTTAATAT ATCAAAGATC AGTTGACATC 3840
TCTAGGGAAT GATGAAACAG CAGGCTATTA GAAAATTATT TCATATAGTT CTCGTGTTCT 3900
TTTCTTTTTT TTAATCCCTG AAGGGAGATC AGTAACATAG CTTCTCTTTT CTGTACTCTA 3960
GACCACCCCT TTTCATCATT TTGCTTTTTA TGTCTCCCAT AAGAAATGTG CTTTTTAGAG 4020
CTTCCTAATβ CATGTGTTGC ATTATTGCAG CATTAGAAAA GGAGAGGTAG CATTTTTGCT 4080
GAAATCGGGC CTGTCACTCT CCAATAAAGG TTCTGβCACT TCAATGCCAG GCAGGTCTCC 4140
TAAATGAACA GAATGATCTG TGTGAGCCGA TGCCTGCCCT TCCAGAGGGG CCACTGTCCC 4200
CAGCCGCAGC CAACTGTGTC CCACAGGAAT GGGAβCCTAG GTTTCCAAAT CTTGT6ATTC 4260
TTTAGGAGAA ACATGAAACC TGGATTTCGT GTGAAATGTC CCGATTGTTA AAAAGTTGGC 4320
TCAATTATTT TTAAAACATT TTGTAAGCCA ACAAAAGTCT GTβββCTGCC AGTTTATTAC 4380
TTTTGTCTTA AAACATGATC ATTGTTCTCT CACGGTATCC TTCTGTCTTC CCGTTGCAAA 4440
TTCACTTTTC TTTCTTCCTG ACATTGCCAT TGAGGGCTTT GTTACCACAA GCTAAGAAAC 4500
TGAGTTTAAC AGCCCA6TTA TCTGCAACAT GTCAATTACC TTTGCTCCTC TCCTGTGATT 4560
CCCACCATGC TGTGACCCTC AGCTGTCTCC CTTTGCTGGG AATTCTGCAC CAATGTCTTC 4620
CCCTCAACCC ATTCCCTGGT TGGTCCTACT CCCCTGTGGC CAGAGACATC CTAGCAAATC 4680
CTTCCTCCTA TTATATCTGA CACTAATTTC TTTTCAACAG CGCTCATGTC TCTTββCCCA 4740
GTCAGGTGCT GCCAGGTTTA GATAGGAAAG TACATGTCCC ATTTTCATGG GTGCCCTTAA 4800
TGTGGTCCAC GTCCTATATC TTATTATATT TACTCATGGC TCAATGGGGG CCTCCAGAGA 4860
CCCTCTCAGG CTGCTGAGCT AGACTAAGGA ATGCATCCAC TGTCATCACA TGAGACACTG 4920
ACTCTGTGAC GACAAAAGTA CAAACAGTCT GAGGCTAAGA AAGGTTCATC TCACAACAGG 4980
AAAAACAAAT CTCAACACAC ATTAGAGATA ATTGATTCAG GGGTTTTCTC TCCCAGTCTC 5040
CCAGCAGGGA CTGATTTCAT TTCTGACCCA CTAβGTTTTC TTTCCAGAAA TAGGTAGCAA 5100
GGACAAGAAC TAAACAATCC CAGCCCCACC CAGCAACACA GAACACAGGA GTTTGCTTTT 5160
GGCTTCTCAC TCTCCAAGTA ACCCTGAATT AGGCCCAGAA TGGCTGAGGC TTGGAGCATC 5220
TCCTCAGACA GAGCAGAGGC GACACCTCTT CAGββGTGTG TGGAβTAAAT AβCTCGAAGA 5280
GCTGAAGACA GAAAACCAGT TTCACGCCAG GTGCβAGAGA GAGCATAATG GAGGGAAGCC 5340
CGCTTTCTCT CTCCTCTTCT TTTCTCTTTA TTTCTTTAβA GCACTTGACT TTTTTTTCTC 5400
TCTCTCTCTA GTATTCTAAA CTGACCCCAT GACCAACTGA GAATTTATTT TTGTTTCATT 5460
GGTTGTTTCA CAβAATTAGA ACACACACGA CTTTTTATTC CTCCATTGCA AAATGGAATC 5520
AAGATACTAC ACAAGACCTG TβCTTTCTTC CTTTGCATGA TTTACACCTC CGCCTGTTTT 5580
GGTGCTAGCT GTCTAGAACT TCTCTCTTGG TTTGAATCTG ATTCCTTCAC ACTACACTAβ 5640
AAGTTTATTT CATCTTGTTT TGTCTAGACT CCAβATACAG AGβGACAGCT GGACTGAG6A 5700
CAAGCAATTC CATCTAGCAT AGGGTCTCTC AGGGTTGGTG CATCCAGCCA CATGGGCAGG 5760
GCCAGTCACA TCTAGTCTAT GTCCCCAβAβ CCCTTGGAGT TGCGCAGCTT AGCTGACTTG 5820
ACTCCAAGGA AATTAGTACA GAAGTAACCA CTCTATTAAG TGTGTTCTGC TATGTTCACA 5880
TGCCTGTAGT ACCTGCAAAC CATGCCAGGT TCATCTAAAG ACATAGGGGA AGATTAAGGA 5940
CTCTTTTβGA CAGACCATGA ATTGAATTTG CTGCCAGGTG CTGCCAGACT GAATTTGGCT 6000
GACAGAACTC CCAGCCCAGG AAAGTTCCAT GACAATGACT GTCGCAGAAG GAAATTTCCC 6060
ACTAAAGTCA GTCCATTTTC AAGTTTTGGT CTTCAGAGAC AAAAGAACGT CCCAGCCACC 6120
TGATTTTGAT GGTGAβGTAA CTCTAAGTTG AATTCAGGCT AGTGTTGCAG TATAGCTTTG 6180 GCATGTTCAT GAGTGAGCAC CCAGAATGTG TTGAACCAAC CCCCACCCCT AACTACTGAC 6240
TATGACTGCA GTGGGTTTTT ATGGGGAAAA AAAGTGTGAA AAGCAAAAAG AAAGGAACAG 6300
AGATTTTTTA TCACCTTTAT TGTAAGACAG TCCATTTATG AATTGAGTAT AAACACATAC 6360
AAAGTAACAA βAGATTCCTA AGAAACGCAA ATCCTTGAGT TTCACGCACT TCATGTTCAA 6420
CCATTTGCTG TAATCCAGAβ GCAGCCTGTG AATCATTCTC ATGCCCTGTT TTTTTTTTTT 6480
TTTTCCTATA ATβTTCTβββ TTTAAAAGCC ATCTTTTCCA CATTTTCTGT AAATAATGGA 6540
TAATCATTTT AAAAAGTTTT ATTTTTAβTβ CTGTTTTAAC AATGTAGATA GATCATAAAT 6600
GTACTTGCTG AATTCAATCA TTTTTAACAA GCCAATAAAG TTTGATAATT CAAAAAAAAA 6660
AAAAAAAAAA AAAAAAAAA 6679
Seq ID NO: CIO9 DNA Sequence
Nucleic Acid Accession #: NM_006180.1
Coding sequence: 352..2820
11 21 31 41 51
CCCCCATTCG CATCTAACAA GGAATCTGCβ CCCCAGAGAG TCCCGGACGC CGCCGβTCββ 60
TGCCCGGCGC GCCGGGCCAT GCAGCGACGβ CCCCCGCGGA GCTCCGAGCA GCGGTAGCGC 120
CCCCCTGTAA AGCGGTTCGC TATGCCGGGA CCACTGTGAA CCCTGCCGCC TGCCGβAACA 180
CTCTTCGCTC CGGACCAGCT CAGCCTCTGA TAAGCTGGAC TCGGCACGCC CGCAACAAGC 240
ACCβAGGAGT TAAGAGAGCC GCAAGCGCAG GGAAGGCCTC CCCGCACGGG TGGGGGAAAG 300
CGGCCGGTGC AGCGCGGGGA CAGGCACTCG GβCTGGCACT GGCTGCTAGG GATGTCGTCC 360
TGGATAAGGT GGCATGGACC CGCCATGGCG CGGCTCTGGG GCTTCTGCTG GCTGGTTGTG 420
GGCTTCTGGA GGGCCGCTTT CGCCTGTCCC ACβTCCTGCA AATβCAGTGC CTCTCGGATC 480
TGGTGCAGCG ACCCTTCTCC TGGCATCGTG GCATTTCCGA GATTGGAGCC TAACAGTGTA 540
GATCCTGAGA ACATCACCGA AATTTTCATC GCAAACCAGA AAAGGTTAGA AATCATCAAC 600
GAAGATGATG TTGAAGCTTA TGTGGGACTG AGAAATCTGA GAATTCTGGA TTCTGGATTA 660
AAATTTGTGG CTCATAAAGC ATTTCTGAAA AACAGCAACC TGCAGCACAT CAATTTTACC 720
CGAAACAAAC TGACGAGTTT GTCTAGGAAA CATTTCCGTC ACCTTGACTT GTCTGAACTG 780
ATCCTβGTGG GCAATCCATT TACATGCTCC TGTGACATTA TGTGGATCAA βACTCTCCAA 840
GAGGCTAAAT CCAGTCCAGA CACTCAGGAT TTGTACTGCC TGAATGAAAG CAGCAAGAAT 900
ATTCCCCTGG CAAACCTGCA GATACCCAAT TGTGGTTTGC CATCTGCAAA TCTGGCCGCA 960
CCTAACCTCA CTGTGGAGGA AGGAAAGTCT ATCACATTAT' CCTGTAGTGT GGCAGGTGAT 1020
CCGGTTCCTA ATATGTATTG GGATGTTGGT AACCTGGTTT CCAAACATAT GAATGAAACA 1080
AGCCACACAC AGGGCTCCTT AAGGATAACT AACATTTCAT CCGATGACAG TGGGAAGCAG 1140
ATCTCTTGTG TGGCGGAAAA TCTTGTAGβA GAAGATCAAG ATTCTGTCAA CCTCACTβTG 1200
CATTTTGCAC CAACTATCAC ATTTCTCβAA TCTCCAACCT CAGACCACCA CTGGTGCATT 1260
CCATTCACTG TGAAAGGCAA CCCCAAACCA GCGCTTCAGT GGTTCTATAA CGGGGCAATA 1320
TTGAATGAGT CCAAATACAT CTGTACTAAA ATACATGTTA CCAATCACAC GGAGTACCAC 1380
GGCTGCCTCC AGCTGGATAA TCCCACTCAC ATGAACAATG GGGACTACAC TCTAATAGCC 1440
AAβAATGAGT ATGGGAAGGA TGAGAAACAG ATTTCTGCTC ACTTCATGGG CTGGCCTGGA 1500
ATTβACGATG GTGCAAACCC AAATTATCCT GATGTAATTT ATGAAGATTA TGGAACTGCA 1560
GCGAATGACA TCGGGGACAC CACGAACAGA AGTAATGAAA TCCCTTCCAC AGACGTCACT 1620
GATAAAACCG GTCGGGAACA TCTCTCGGTC TATGCTCTGG TGGTGATTGC GTCTGTGGTG 1680
GGATTTTGCC TTTTGGTAAT GCTGTTTCTG CTTAAGTTGG CAAGACACTC CAAGTTTGGC 1740
ATGAAAGGCC CAGCCTCCGT TATCAGCAAT GATGATGACT CTGCCAGCCC ACTCCATCAC 1800
ATCTCCAATG GGAGTAACAC TCCATCTTCT TCGGAAGGTG GCCCAGATGC TGTCATTATT 1860
GGAATGACCA AGATCCCTGT CATTGAAAAT CCCCAGTACT TTGβCATCAC CAACAβTCAG 1920
CTCAAGCCAG ACACATTTGT TCAGCACATC AAGCGACATA ACATTGTTCT GAAAAGGGAG 1980
CTAGGCGAAG GAGCCTTTGG AAAAGTGTTC CTAGCTGAAT GCTATAACCT CTGTCCTGAG 2040
CAGGACAAGA TCTTGGTGGC AGTGAAGACC CTGAAGGATG CCAGTGACAA TβCACGCAAG 2100
GACTTCCACC GTβAGGCCGA βCTCCTβACC AACCTCCAGC ATGAGCACAT CGTCAAGTTC 2160
TATGGCCTCT GCGTGGAGGG CGACCCCCTC ATCATGGTCT TTGAGTACAT GAAGCATGGG 2220
GACCTCAACA AGTTCCTCAG GβCACACGGC CCTGATβCCG TGCTGATGGC TGAGGβCAAC 2280
CCGCCCACGG AACTGACβCA GTCGCAGATG CTGCATATAG CCCAGCAGAT CGCCβCGGGC 2340
ATGGTCTACC TGGCGTCCCA GCACTTCGTG CACCGCGATT TGGCCACCAG GAACTGCCTG 2400
GTCGGGGAGA ACTTGCTGGT GAAAATCGGG GACTTTGGGA TGTCCCGGGA CGTGTACAGC 2460
ACTGACTACT ACAGGGTCGG TGGCCACACA ATGCTGCCCA TTCβCTGGAT GCCTCCAGAG 2520
AGCATCATGT ACAGGAAATT CACGACGGAA AGCGACGTCT GGAGCCTGGG GGTCGTGTTG 2580
TGGGAGATTT TCACCTATGG CAAACAGCCC TGGTACCAGC TGTCAAACAA TGAGGTGATA 2640
GAGTGTATCA CTCAGGGCCG AGTCCTGCAG CGACCCCGCA CGTGCCCCCA GGAGGTGTAT 2700
GAGCTGATGC TGGGβTGCTG GCAGCβAβAG CCCCACATGA GGAAGAACAT CAAGGβCATC 2760
CATACCCTCC TTCAβAACTT GGCCAAGβCA TCTCCGGTCT ACCTGGACAT TCTAGGCTAG 2820
GGCCCTTTTC CCCAGACCGA TCCTTCCCAA CGTACTCCTC AGACGGGCTG AGAGGATGAA 2880
CATCTTTTAA CTGCCGCTGβ AGGCCACCAA GCTGCTCTCC TTCACTCTGA CAGTATTAAC 2940
ATCAAAGACT CCGAGAAGCT CTCGAGGGAA GCA6TGTGTA CTTCTTCATC CATAGACACA 3000
GTATTGACTT CTTTTTGGCA TTATCTCTTT CTCTCTTTCC ATCTCCCTTG GTTGTTCCTT 3060
TTTCTTTTTT TAAATTTTCT TTTTCTTCTT TTTTTTCGTC TTCCCTGCTT CACGATTCTT 3120
ACCCTTTCTT TTGAATCAAT CTGGCTTCTG CATTAGTATT AACTCTGCAT AGACAAAGGC 3180
CTTAACAAAC βTAATTTGTT ATATCAGCAG ACACTCCAGT TTGCCCACCA CAACTAACAA 3240
TβCCTTCTTG TATTCCTGCC TTTβATβTGG ATGAAAAAAA GGGAAAACAA ATATTTCACT 3300
TAAACTTTGT CACTTCTGCT GTACAGATAT CGAGAGTTTC TATGGATTCA CTTCTATTTA 3360
TTTATTATTA TTACTGTTCT TATTGTTTTT GGATGGCTTA AGCCTGTGTA TAAAAAAGAA 3420
AACTTGTGTT CAATCTGTGA AGCCTTTATC TATGGGAGAT TAAAACCAGA GAGAAAGAAG 3480
ATTTATTATG AACCGCAATA TGGGAGGAAC AAAGACAACC ACTGGGATCA GCTGGTGTCA 3540
GTCCCTACTT AGGAAATACT CAGCAACTGT TAGCTCGGAA GAATGTATTC GGCACCTTCC 3600
CCTGAGβACC TTTCTGAGGA GTAAAAAGAC TACTGGCCTC TGTGCCATGG ATGATTCTTT 3660
TCCCATCACC AGAAATGATA GCGTGCAGTA GAGAGCAAAG ATGGCTT 3707
Seq ID NO: C110 DNA Sequence
Nucleic Acid Accession tf: Eos sequence
Coding sequence: 939..2372
31 I I I I I I
AAGACGGATT CTCAGACAAG GCTTGCAAAT GCCCCGCAGC CATCATTTAA CTGCACCCGC 60
AGAATAGTTA CGGTTTGTCA CCCGACCCTC CCGGATCGCC TAATTTβTCC CTAGTGAGAC 120
CCCGAGGCTC TGCCCGCGCC TGGCTTCTTC GTAGCTGGAT GCATATCGTG CTCCGGGCAG 180
CGCGGGCGCA GGGCACGCGT TCGCGCACAC CCTAGCACAC ATGAACACGC GCAAGAGCTG 240
AACCAAGGAC GGTTTCCATT TCAAAAAGGG AGACAGCCTC TACCGCGATT GTAGAAGAGA 300
CTGTGGTGTG AATTAGGGAC CGGGAGGCGT CGAACGGAGG AACGGTTCAT CTTAGA6ACT 360
AATTTTCTGG AGTTTCTGCC CCTGCTCTβC GTCAGCCCTC ACGTCACTTC GCCAGCAGTA 420
GCAGAGGCGG CGGCGGCGGC TCCCGGAATT GGGTTGGAGC AGGAGCCTCG CTββCTGCTT 480
CGCTCGCβCT CTACGCGCTC AGTCCCCGGC GGTAGCAGGA GCCTGGACCC AGGCGCCGCC 540
GGCGβGCGTG AGGCGCCGGA GCCCGGCCTC GAGGTGCATA CCGGACCCCC ATTCGCATCT 600
AACAAGGAAT CTGCGCCCCA GAGAGTCCCG GGAGCGCCGC CGGTCGβTβC CCGGCGCGCC 660
GGβCCATGCA GCGACGGCCG CCGCGGAGCT CCGAGCAGCG GTAGCβCCCC CCTGTAAAGC 720
GGTTCCCTAT βCCGGGGCCA CTGTGAACCC TGCCGCCTGC CGGAACACTC TTCGCTCCGG 780
ACCAGCTCAG CCTCTGATAA GCTGGACTGG GCACGCCCGC AACAAGCACC GAGGAGTTAA 840
GAGAGCCβCA AGCGCAGGGA AGGCCTCCCC GCACGGGTGG GGGAAAGCββ CCGGTGCAGC 900
GCGGGGACAG GCACTCGGGC TGGCACTGGC TGCTAGGGAT GTCGTCCT6G ATAAGGTGGC 960
ATGGACCCGC CATGGCGCGG CTCTGGGGCT TCTGCTGGCT GGTTGTGGGC TTCTGGAGGG 1020
CCGCTTTCGC CTGTCCCACG TCCTGCAAAT GCAGTGCCTC TCGGATCTGG TGCAGCGACC 1080
CTTCTCCTGG CATCGTGGCA TTTCCGAGAT TGGAGCCTAA CAGTGTAGAT CCTGAGAACA 1140
TCACCGAAAT TTTCATCGCA AACCAGAAAA GGTTAGAAAT CATCAACGAA GATGATGTTG 1200
AAGCTTATGT GGGACTGAGA AATCTGACAA TTGTGGATTC TGGATTAAAA TTTCTGGCTC 1260
ATAAAGCATT TCTGAAAAAC AGCAACCTGC AGCACATCAA TTTTACCCGA AACAAACTGA 1320
CGAGTTTGTC TAGGAAACAT TTCCCTCACC TTGACTTGTC TGAACTGATC CTGGTGGGCA 1380
ATCCATTTAC ATGCTCCTGT GACATTATGT GGATCAAGAC TCTCCAAGAG GCTAAATCCA 1440
GTCCAGACAC TCAGGATTTG TACTGCCTGA ATGAAAGCAG CAAGAATATT CCCCTGβCAA 1500
ACCTGCAGAT ACCCAATTGT GGTTTGCCAT CTGCAAATCT GGCCGCACCT AACCTCACTG 1560
TGGAGGAAGG AAAβTCTATC ACATTATCCT GTAGTGTGGC AGGTGATCCG GTTCCTAATA 1620
TGTATTGGGA TGTTGβTAAC CTGGTTTCCA AACATATGAA TGAAACAAGC CACACACAGG 1680
GCTCCTTAAG GATAACTAAC ATTTCATCCG ATGACAGTGG GAAGCAGATC TCTTGTGTGG 1740
CGGAAAATCT TGTAGGAGAA GATCAAβATT CTGTCAACCT CACTGTGCAT TTTGCACCAA 1800
CTATCACATT TCTCGAATCT CCAACCTCAG ACCACCACTβ GTGCATTCCA TTCACTGTβA 1860
AAGGCAACCC GAAACCAGCC CTTCAGTGGT TCTATAACGG GGCAATATTG AATGAGTCCA 1920
AATACATCTG TACTAAAATA CATGTTACCA ATCACACGGA GTACCACGGC TGCCTCCAGC 1980
TGGATAATCC CACTCACATG AACAATββGG ACTACACTCT AATAGCCAAG AATGAGTATG 2040
GβAAGGATGA GAAACAGATT TCTGCTCACT TCATGβGCTG GCCTGGAATT GACGATβGTG 2100
CAAACCCAAA TTATCCTGAT GTAATTTATG AAGATTATGG AACTGCAGCG AATGACATCG 2160
GGGACACCAC GAACAGAAGT AATGAAATCC CTTCCACAGA CGTCACTGAT AAAACCGGTC 2220 ββGAACATCT CTCGGTCTAT GCTGTGGTGG TGATTGCGTC TGTGGTGGGA TTTTGCCTTT 2280
TββTAATGCT GTTTCTGCTT AAGTTGGCAA GACACTCCAA GTTTGGCATG AAAGGTTTTG 2340
TTTTGTTTCA TAAGATCCCA CTGβATGGGT AGCTGAAATA AAGGAAAAGA CAGAGAAAGG 2400
GGCTGTGGTG CTTGTTGGTT GATGCTβCCA TGTAAβCTGG ACTCCTGGGA CTGCTGTTGG 2460
CTTATCCCGG GAAGTGCTGC TTATCTββGG TTTTCTG6TA GATGTGGGCG GTGTTTGGAG 2520
GCTGTACTAT ATGAAGCCTG CATATACTGT GAGCTGTβAT TGGGGAACAC CAATGCACAG 2580
GTAACTCTCA GGCAGCTAAG CAGCACCTCA AGAAAACATG TTAAATTAAT GCTTCTCTTC 2640
TTACAGTAGT TCAAATACAA AACTGAAATG AAATCCCATT GGATTGTACT TCTCTTCTGA 2700
AAAGTGTGCT TTTTGACCCT ACTGGACATT TATTGACTTA ATTGCTTCTG TTTATTAAAA 2760
TTGACCTGCA AAβTTAAAAA AAAATTAAAβ TTGAGAACAG GTATAAGTGC ACACTGAATA 2820
GTCTAATCTA CATGTAACAC ATATTTTAGT GTGATTTTCT ATACTCTAAT CAGCACTGAA 2880
TTCAGAGGβT TTGACTTTTT CATCTATAAC ACAGTβACTA AAAGAGTTAA GG6TATATAT 2940
ACCATCACTT TGGGACTTGG TAGTATTATT AAAAGGTTAT TTCCTTCACT GTCAATAAAA 3000
GTCCAAATGT TTAGCTTAGG TCTGAGAGTC AAACAATGTT AAGGATTGTC TTAAAGTTCC 3060
TTACCCAGCA AAACAAAACA AAACAAAACA AACAAATGAA AAACGTTTAA AAAGAAGAAG 3120
AAGAAAAAAA ACAAGAACAA GCAGCAACAG CTGTTTTGTT GGGGCTATAG ATTTAAGTTA 3180
GGCATAGTCA ATTTCAGAAT AACTAAGAGT GGAATATATG CATATGGTGA AATTATAACC 3240
TTGCCCTTTT TTATTTGCCC TCTGCβATCC ACCTGCTTTT TAGAAGTCTG CCGAGTGAGA 3300
AGGCCACAGT ATCTCATGCT GTTTGCATTA GAGAACTGCA GCTTTTCTAC TCTGAAAAGβ 3360
CCTGGGAβCA GAATGGCTGG CCTGCTGTGA GCAGGAGAGβ AGATTCTAAG AAGGATAGTC 3420
CCCCCTACAA CATACTGTCA TACTGCTGGG TTTTCATGGG TAGGAAAGCT TGTCCTGACC 3480
CCAGCAGCAA AGAGGTGGCA GGTCGCTAAT GAATATATGC TTTATAATGT CCTTCTTCAT 3540
TGCTGAGAGG GCAGCCTTAG AGCTGTGGAT TTCTGCATCC CCCCTβAGTC TGACCCATGG 3600
AGACCTGTTT CATTCACTTT AGCATCACAG TGACCTTTGT ATGCTCTGTT CAGTCTGTGT 3660
CAββCAGTAT GCTTGTCCTG AAGA6AGGTT TGGCTATCCC CACCCCACCC CACCCCACCC 3720
TGTTCCTTTT TTATCAGβAβ GACTTCAGAG CCAGGCCTGC AGCATTTTGT TTGAAAACAC 3780
AATCAβCTCT βACAGTTAGA CATGCACACA GACGCCATAG CTGGATTGGA AACATTGATG 3840
TTTTAAAAAT TTATTTTTTT TGGAAATAGT TGCACAAATG CTGCAATTTA GCTTTAAGGT 3900
TCTATAGATT TTTAACTAGT CCAACACAGT CAGAAACATT GTTTTGAATC CTCTβTAAAC 3960
CAAGGCATTA ATCTTAATAA ACCAGGATCC ATTTAβGTAC CACTTGATAT AAAAAGGATA 4020
TCCATAATGA ATATTTTATA CTGCATCCTT TACATTAGCC ACTAAATACG TTATTGCTTG 4080
ATGAAGACCT TTCACAGAAT CCTATGGATT GCAGCATTTC ACTTGGCTAC TTCATACCCA 4140
TGCCTTAAAG AGGGGCAGTT TCTCAAAAGC AGAAACATGC CGCCAGTTCT CAAGTTTTCC 4200
TCCTAACTCC ATTTGAATβT AAββGCAGCT GGCCCCCAAT GTGGGGAGGT CCGAACATTT 4260
TCTGAATTCC CATTTTCTTG TTCGCGGCTA AATGACAGTT TCTGTCATTA CTTAGATTCC 4320
GATCTTTCCC AAAGGTGTTG ATTTACAAAG AGGCCAGCTA ATAGCAGAAA TCATGACCCT 4380
GAAAGAGAGA TGAAATTCAA GCTGTGAGCC AGGCAGGAGC TCAGTATGGC AAAGβTTCTT 4440
GAGAATCAGC CATTTGGTAC AAAAAAGATT TTTAAAGCTT TTATGTTATA CCATGGAGCC 4500 ATAGAAAGGC TATGGATTGT TTAAGAACTA TTTTAAAGTβ TTCCAGACCC AAAAAGGAAA 4560 AATAAAAAAA AAGGAATATT TGTACCCAAC AGCTAGAAβG ATTGCAAGGT AGATTTTTGT 4620 TTTAAAATGG AGAGAAGTGG ACAGATAAGG CCATTTAATA TATCAAAGAT CAGTTGACAT 4680 CTCCTAGβGA ATGATGAAAA CAGCAGGCTA T 4711
Seq ID NO: Clll DNA Sequence
Nucleic Acid Accession #: NM_130830.1
Coding sequence: 1..1746 ATGCCACTGA AGCATTATCT CCTTTTGCTG GTGGGCTGCC AAGCCTGGGG TGCAGGGTTG 60
GCCTACCATG GCTGCCCTAG CGAGTGTACC TGCTCCAGββ CCTCCCAGGT G6A6TGCACC 120
GGGGCACGCA TTGTGGCGGT GCCCACCCCT CTGCCCTGGA ACGCCATGAG CCTGCAGATC 180
CTCAACACβC ACATCACTGA ACTCAATGAβ TCCCCGTTCC TCAATATCTC AGCCCTCATC 240
GCCCTGAGGA TTGAGAAGAA TGAGCTGTCG CGCATCACβC CTGGGGCCTT CCGAAACCTG 300
GGCTCGCTGC GCTATCTCAG CCTCGCCAAC AACAAGCTGC AGGTTCTGCC CATCGGCCTC 360
TTCCAGGβCC TGGACAGCCT TGAGTCTCTC CTTCTβTCCA GTAACCAGCT GTTGCAGATC 420
CAGCCGGCCC ACTTCTCCCA GTGCAGCAAC CTCAAGGAGC TGCAGTTGCA CGGCAACCAC 480
CTCGAATACA TCCCTGACGG AGCCTTCGAC CACCTGGTAG GACTCACGAA CCTCAATCTG 540
GGCAAGAATA GCCTCACCCA CATCTCACCC AGβGTCTTCC AGCACCTGGG CAATCTCCAG 600
GTCCTCCGβC TGTATGAGAA CAGGCTCACG GATATCCCCA TGGGCACTTT TGATGGGCTT 660
GTTAACCTGC AGGAACTGGC TCTACAGCAG AACCAGATTG GACTGCTCTC CCCTGGTCTC 720
TTCCACAACA ACCACAACCT CCAGAGACTC TACCTGTCCA ACAACCACAT CTCCCAGGTG 780
CCACCCAGCA TCTTCATGCA GCTGCCCCAG CTCAACCGTC TTACTCTCTT TGGβAATTCC 840
CTGAAGGAGC TCTCTCTGGG GATCTTCGββ CCCATGCCCA ACCTGCGGGA GCTTTGGCTC 900
TATGACAACC ACATCTCTTC TCTACCCβAC AATGTCTTCA GCAACCTCCG CCAGTTGCAG 960
6TCCTGATTC TTAGCCGCAA TCAGATCAGC TTCATCTCCC CGGGTGCCTT CAACGGGCTA 1020
ACGGAGCTTC GGGAGCTGTC CCTCCACACC AACGCACTGC AGGACCTGGA CGβGAATGTC 1080
TTCCGCATGT TGGCCAACCT GCAGAACATC TCCCTGCAGA ACAATCGCCT CAGACAGCTC 1140
CCAGGGAATA TCTTCGCCAA CGTCAATGGC CTCATGGCCA TCCAGCTGCA GAAGAACCAG 1200
CTGGAGAACT TGCCCCTCGG CATCTTCGAT CACCTGGGGA AAGTGTGTGA GCTGCGGCTG 1260
TATGACAATC CCTGβAGGTG TGACTCAGAC ATCCTTCCGC TCCGCAACTG GCTCCTGCTC 1320
AACCAGCCTA GGTTAGβGAC GGACACTGTA CCTGTGTGTT TCAGCCCAGC CAATGTCCGA 1380
GGCCAGTCCC TCATTATCAT CAATGTCAAC GTTGCTGTTC CAAGCGTCCA TGTCCCTβAβ 1440
GTGCCTAGTT ACCCAGAAAC ACCATGGTAC CCAGACACAC CCAGTTACCC TβACACCACA 1500
TCCGTCTCTT CTACCACTGA GCTAACCAGC CCTGTGGAAG ACTACACTGA TCTGACTACC 1560
ATTCAGGTCA CTGATGACCG CAGCGTTTGG ββCATGACCC AGGCCCAGAG CGGGCTGGCC 1620
ATTGCCβCCA TTGTAATTGG CATTGTCGCC CTGGCCTGCT CCCTGGCTGC CTGCGTCGGC 1680
TGTTGCTGCT GCAAGAAGAG GAGCCAAGCT GTCCTGATGC AGATGAAGGC ACCCAATGAG 1740
TGTTAA 1746
Seq ID NO: C112 DNA Sequence
Nucleic Acid Accession #: NM_002658.1
Coding sequence: 77..1372
1 11 21 31 41 51 1 1 1 | 1 | 1 1 1
GTCCCCGCAG CGCCGTCGCG CCCTCCTGCC GCAGGCCACC GAGGCCGCCG CCGTCTAGCG 60
CCCCGACCTC GCCACCATGA GAGCCCTGCT GGCGCGCCTG CTTCTCTGCG TCCTGGTCGT 120
GAGCGACTCC AAAGGCAGCA ATGAACTTCA TCAAGTTCCA TCGAACTGTG ACTGTCTAAA 180
TGGAGGAACA TGTGTGTCCA ACAAGTACTT CTCCAACATT CACTGGTGCA ACTGCCCAAA 240
GAAATTCGGA GGGCAGCACT GTGAAATAGA TAAGTCAAAA ACCTGCTATG AGGGGAATGG 300
TCACTTTTAC CGAGGAAAGG CCAGCACTGA CACCATGββC CGGCCCTGCC TGCCCTGGAA 360
CTCTGCCACT GTCCTTCAGC AAACGTACCA TGCCCACA6A TCTGATGCTC TTCAGCTGβG 420
CCTGGGβAAA CATAATTACT GCAGGAACCC AβACAACCGβ AGGCGACCCT GGTGCTATGT 480
GCAGGTGGGC CTAAAGCCGC TTGTCCAAGA GTGCATGGTG CATGACTGCG CAGATGGAAA 540
AAAGCCCTCC TCTCCTCCAG AAGAATTAAA ATTTCAGTGT GGCCAAAAGA CTCTGAGGCC 600
CCGCTTTAAG ATTATTGGGG GAGAATTCAC CACCATCGAG AACCAGCCCT GGTTTGCGGC 660
CATCTACAGG AGGCACCGGG GGGGCTCTGT CACCTACGTG TGTGGAGGCA GCCTCATCAG 720
CCCTTGCTGG GTGATCAGCG CCACACACTβ CTTCATTGAT TACCCAAAGA AGGAβGACTA 780
CATCGTCTAC CTGβGTCGCT CAAGGCTTAA CTCCAACACG CAAGGGGAGA TGAAGTTTGA 840
GGTGGAAAAC CTCATCCTAC ACAAGGACTA CAGCGCTGAC ACGCTTGCTC ACCACAACGA 900
CATTGCCTTG CTGAAGATCC GTTCCAAGGA GGGCAGGTGT GCGCAβCCAT CCCGGACTAT 960
ACAGACCATC TCCCTGCCCT CGATGTATAA CGATCCCCAβ TTTGGCACAA GCTGTGAGAT 1020
CACTGGCTTT GGAAAAGAGA ATTCTACCGA CTATCTCTAT CCGGAβCAGC TGAAAATGAC 1080
TGTTGTGAAG CTGATTTCCC ACCGGGAGTβ TCAGCAGCCC CACTACTACG GCTCTGAAGT 1140
CACCACCAAA ATGCTATGTG CTGCTGACCC CCAATGGAAA ACAGATTCCT GCCAGGGAGA 1200
CTCAGGGGGA CCCCTCGTCT GTTCCCTCCA AG6CCGCATG ACTTTGACTG GAATTGTGAG 1260
CTGGGGCCGT GGATGTGCCC TGAAGGACAA GCCAGGCGTC TACACGAGAG TCTCACACTT 1320
CTTACCCTGG ATCCGCAGTC ACACCAAGGA AGAGAATGGC CTGGCCCTCT GAGGGTCCCC 1380
AGGGAGGAAA CGGGCACCAC CCGCTTTCTT GCTGGTTGTC ATTTTTGCAG TAGAGTCATC 1440
TCCATCAGCT GTAAGAAGAG ACTGGGAAGA TAGGCTCTGC ACAGATGGAT TTGCCTGTGG 1500
CACCACCAGG GTGAACGACA ATAGCTTTAC CCTCACGGAT AGGCCTβGGT GCTGGCTGCC 1560
CAGACCCTCT GGCCAGGATG GAGGGGTGGT CCTGACTCAA CATGTTACTG ACCAGCAACT 1620
TGTCTTTTTC TGGACTGAAG CCTGCAGGAG TTAAAAAGββ CAGGGCATCT CCTGTGCATG 1680
GGCTCGAAGG GAGAGCCAGC TCCCCCGACC GβTGGGCATT TGTGAGGCCC ATGβTTGAGA 1740
AATGAATAAT TTCCCAATTA GGAAGTGTAA GCAGCTGAGG TCTCTTGAGG GAGCTTAGCC 1800
AATGTGGGAG CAGCGGTTTG GGGAGCAGAG ACACTAACGA CTTCAGGGCA GGGCTCTGAT 1860
ATTCCATGAA TGTATCAGGA AATATATATG TGTGTGTATG TTTGCACACT TGTTGTGTGG 1920
GCTGTGAGTG TAAGTβTGAG TAAGAGCTGG TGTCTGATTG TTAAGTCTAA ATATTTCCTT 1980
AAACTGTGTG GACTGTGATG CCACACAGAG TGGTCTTTCT GGAGAβGTTA TAGGTCACTC 2040
CTGGGGCCTC TTGGGTCCCC CACGTGACAG TGCCTGGGAA TGTACTTATT CTGCAGCATβ 2100
ACCTGTGACC AGCACTGTCT CAGTTTCACT TTCACATAGA TGTCCCTTTC TTGGCCAGTT 2160
ATCCCTTCCT TTTAGCCTAG TTCATCCAAT CCTCACTGGG TGGGGTGAGG ACCACTCCTT 2220
ACACTGAATA TTTATATTTC ACTATTTTTA TTTATATTTT TGTAATTTTA AATAAAAGTG 2280
ATCAATAAAA TGTGATTTTT CTGA 2304
Seq ID NO: C113 DNA Sequence
Nucleic Acid Accession #: XM_087254.1
Coding sequence: 47.-2332 1 11 21 31 41 51
I I I I I I
AGAGTACGTG TTTACAGATA AAACTGGTAC ACTGACAGAA AATGAGATGC AGTTTCGGGA 60
ATGTTCAATT AATGGCATGA AATACCAAGA AATTAATGGT AGACTTGTAC CCGAAGGACC 120
AACACCAGAC TCTTCAGAAG GAAACTTATC TTATCTTAGT AGTTTATCCC ATCTTAACAA 180
CTTATCCCAT CTTACAACCA GTTCCTCTTT CAGAACCAGT CCTGAAAATG AAACTGAACT 240
AATTAAAGAA CATGATCTCT TCTTTAAAGC AGTCAGTCTC TGTCACACTG TACAGATTAG 300
CAATGTTCAA ACTGACTGCA CTCGTGATGG TCCCTGβCAA TCCAACCTGG CACCATCGCA 360
GTTGGAGTAC TATGCATCTT CACCAGATGA AAAGGCTCTA GTAGAAGCTG CTGCAAGβAT 420
TGGTATTβTG TTTATTGGCA ATTCTGAAGA AACTATGGAG GTTAAAACTC TTGGAAAACT 480
GGAACGGTAC AAACTGCTTC ATATTCTGGA ATTTGATTCA GATCGTAGGA GAATGAGTGT 540
AATTGTTCAG GCACCTTCAG GTGAGAAGTT ATTATTTβCT AAAGGAGCTG AGTCATCAAT 600
TCTCCCTAAA TGTATAGGTG GAGAAATAGA AAAAACCAGA ATTCATGTAG ATGAATTTGC 660
TTTGAAAβGG CTAAGAACTC TGTGTATAGC ATATAGAAAA TTTACATCAA AAGAGTATGA 720
GGAAATAβAT AAACGCATAT TTGAAGCCAG GACTGCCTTG CAGCAGCGGG AAGAGAAATT 780
GGCAGCTGTT TTCCAGTTCA TAGAGAAAGA CCTGATATTA CTTGGAGCCA CAGCAGTAGA 840
AGACAGACTA CAAGATAAAG TTCGAGAAAC TATTGAAGCA TTGAGAATGG CTGGTATCAA 900
AGTATGGGTA CTTACTGGβG ATAAACATGA AACAGCTGTT AGTGTGAGTT TATCATGTGG 960
CCATTTTCAT AGAACCATGA ACATCCTTGA ACTTATAAAC CAGAAATCAG ACAGCGAβTG 1020
TGCTGAACAA TTGAGGCAGC TTGCCAGAAG AATTACAGAG GATCATGTGA TTCAGCATGG 1080
GCTGGTAGTG GATGGGACCA GCCTATCTCT TGCACTCAGG GAGCATGAAA AACTATTTAT 1140
GGAAGTTTGC AGAAATTβTT CAGCTGTATT ATGCTGTCGT ATGGCTCCAC TGCAGAAAGC 1200
AAAAGTAATA AGACTAATAA AAATATCACC TGAGAAACCT ATAACATTGG CTGTTGGTGA 1260
TGGTGCTAAT GACGTAAGCA TGATACAAGA AGCCCATGTT GGCATAGGAA TCATGGGTAA 1320
AGAAGGAAGA CAGGCTGCAA GAAACAGTGA CTATGCAATA GCCAGATTTA AGTTCCTCTC 1380
CAAATTGCTT TTTGTTCATG GTCATTTTTA TTATATTAGA ATAGCTACCC TTGTACAGTA 1440
TTTTTTTTAT AAGAATGTGT GCTTTATCAC ACCCCAGTTT TTATATCAGT TCTACTGTTT 1500
GTTTTCTCAG CAAACATTGT ATGACAGCGT GTACCTGACT TTATACAATA TTTCTTTTAC 1560
TTCCCTACCT ATTCTGATAT ATAGTCTTTT GGAACAGCAT GTAGACCCTC ATGTGTTACA 1620
AAATAAGCCC ACCCTTTATC GAGACATTAG TAAAAACCGC CTCTTAAGTA TTAAAACATT 1680
TCTTTATTGG ACCATCCTGG GCTTCAGTCA TGCCTTTATT TTCTTTTTTG GATCCTATTT 1740
ACTAATAGGG AAAGATACAT CTCTGCTTGG AAATGGCCAG ATGTTTGGAA ACTGGACATT 1800
TGGCACTTTG GTCTTCACAG TCATGGTTAT TACAGTCACA GTAAAGATGG CTCTGGAAAC 1860
TCATTTTTGG ACTTGGATCA ACCATCTCGT TACCTGGGGA TCTATTATAT TTTATTTTGT 1920
ATTTTCCTTG TTTTATGGAG GGATTCTCTG GCCATTTTTG GGCTCCCAGA ATATGTATTT 1980
TGTGTTTATT CAGCTCCTGT CAAGTGGTTC TGCTTGGTTT GCCATAATCC TCATGGTTGT 2040
TACATGTCTA TTTCTTGATA TCATAAAGAA GGTCTTTGAC CGACACCTCC ACCCTACAAG 2100
TACTGAAAAG GCACAGCTTA CTCAAACAAA TGCAGGTATC AAGTGCTTGG ACTCCATGTG 2160
CTβTTTCCCG GAAGGAGAAβ CAGCGTβTGC ATCTGTTGGA AGAATGCTGG AACGAβTTAT 2220
AGGAAGATGT AGTCCAACCC ACATCAGCAG ATCATGGAGT GCATCGGATC CTTTCTATAC 2280
CAACGACAGG AGCATCTTGA CTCTCTCCAC AATGGACTCA TCTACTTGTT AAAGGGGCAG 2340
TAGTACTTTG TGGGAGCCAβ TTCACCTCCT TTCCTAAAAT TCAβTGTGAT CACCCTGTTA 2400
ATGGCCACAC TAGCTCTGAA ATTAATTTCC AAAATCTTTG TAGTAGTTCA TACCCACTCA 2460
GAGTTATAAT GGCAAACAAA CAGAAAβCAT TAGTACAAGC CCCTCCCAAC ACCCTTAATT 2520
TGAATCTGAA CATGTTAAAA TTTGAGAATA AAGAGACATT TTTCATCTCT TTGTCTGGTT 2580
TGTCCCTTGT GCTTATGGGA CTCCTAATGG CATTTCAGTC TGTTGCTGAG GCCATTATAT 2640
TTTAATATAA ATGTA6AAAA AAGAGAGAAA TCTTAGTAAA GAGTATTTTT TAGTATTAGC 2700
TTGATTATTG ACTCTTCTAT TTAAATCTGC TTCTGTAAAT TATGCTGAAA GTTTGCCTTG 2760
AGAACTCTAT TTTTTTATTA GAGTTATATT TAAAGCTTTT CATGGGAAAA GTTAATGTGA 2820
ATACTGAGGA ATTTTGGTCC CTCAGTGACC TGTGTTGTTA ATTCATTAAT GCATTCTGAG 2880
TTCACAGAGC AAATTAGGAG AATCATTTCC AACCATTATT TACTGCAGTA TGGGGAGTAA 2940
ATTTATACCA ATTCCTCTAA CTGTACTGTA ACACAGCCTG TAAAGTTAGC CATATAAATG 3000
CAAGGGTATA TCATATATAC AAATCAGGAA TCAGGTCCGT TCACCGAACT TCAAATTGAT 3060 βTTTACTAAT ATTTTTCTGA CAGAGTATAA AGACCCTATA GTGGGTAAAT TAGATACTAT 3120
TAGCATATTA TTAATTTAAT GTCTTTATCA TTGGATCTTT TGCATGCTTT AATCTGGTTA 3180
ACATATTTAA ATTTGCTTTT TTTCTCTTTA CCTβAAββCT CTGTGTATAG TATTTCATGA 3240
CATCGTTGTA CAGTTTAACT ATATCAATAA AAAGTTTGGA CAGTATTTAA ATATTGCAAA 3300
TATGTTTAAT TATACAAATC AGAATAGTAT GGGTAATTAA ATGAATACAA AAAGAAGAGC 3360
CTCTTTCTGC AGCCGACTTA GACATGCTCT TCCCTTTCTA TAAGCTAGAT TTTAGAATAA 3420
AGGGTTTCAG TTAATAATCT TATTTTCAGG TTATGTCATC TAACTTATAG CAAACTACCA 3480
CAATACAGTG AGTTCTGCCA GTGTCCCAGT ACAAGGCATA TTTCAGGTGT GGCTGTGGAA 3540
TGTAAAAATG CTCAACTTGT ATCAGGTAAT GTTAGCAATA AATTAAATGC TAAGAATGAT 3600
TAATCGGGTA CATGTTACTG TAATTAACTC ATTGCACTTC AAAACCTAAC TTCCATCCTG 3660
AATTTATCAA GTAGTTCAGT ATTGTCATTT GTTTTTGTTT TATTGAAAAG TAATGTTGTC 3720
TTAAGATTTA GAAGTGATTA TTAGCTTGAG AACTATTACC CAGCTCTAAG CAAATAMGA 3780
TTGTATACAT ATTAAGATAA TGGTTAAATG CGGTTTTACC AAGTTTTCCC TTGAAAATGT 3840
AATTCCTTTA TGGAGATTTA TTGTGCAGCC CTAAGCTTCC TTCCCATTTC ATGAATATAA 3900
GGCTTCTAGA ATTGGACTGG CAGGGGAAAG AATGGTAGAG ACAGAAATTA AGACTTTATC 3960
CTTGTTTGCT TGTAAACTAT TATTTTCTTG CTAATGTAAC ATTTGTCTGT TCCAGTGATβ 4020
TAAGGATATT AAGTTATTAA GCTAAATATT AATTTTCAAA AATAGTCCTT CTTTAACTTA 4080
GATATTTCAT AGCTGGATTT AGGAAGATCT GTTATTCTGG AAGTACTAAA AAGAATAATA 4140
CAACGTACAA TGTCTGCATT CACTAATTCA TGTTCCAGAA GAGGAAATAA TGAAGATATA 4200
CTCAGTAGAG TACTAGGTGβ GAGGATATGG AAATTTGCTC ATAAAATCTC TTATAAAACG 4260
TGCATATAAC AAAATGACAC CCAGTAGβCC TGCATTACAT TTACATGACC GTGTTTATTT 4320
GCCATCAAAT AAACTGAGTA CTGACACCAG ACAAAGACTC CAAAGTCATA AAATAGCCTA 4380
TGACCAACTG CAGCAAGACA GGAGGTCAGC TCGCCTATAA TGGTGCTTAA AGTGTGATTG 4440
ATGTAATTTT CTGTACTCAC CATTTGAAGT TAGTTAAGGA GAACTTTATT TTTTTAAAAA 4500
AAGTAAATGG CAACCACTAG TGTGCTCATC CTGAACTGTT ACTCCAAATC CACTCCGTTT 4560
TTAAAGCAAA ATTATCTTGT GATTTTAAGA AAAGAGTTTT CTATTTATTT AAGAAAGTAA 4620
CAATGCAGTC TGCAAGCTTT CAGTAGTTTT CTAGTGCTAT ATTCATCCTG TAAAACTCTT 4680
ACTACGTAAC CAGTAATCAC AAGGAAAGTG TCCCCTTTβC ATATTTCTTT AAAATTCTTT 4740
CTTTGGAAAG TATGATGTTG ATAATTAACT TACCCTTATC TGCCAAAACC AGAGCAAAAT 4800 GCTAAATACG TTATTGCTAA TCAGTGGTCT CAAATCGATT TGCCTCCCTT TGCCTCGTCT 4860 GAGGGCTGTA AGCCTGAAGA TAGTGGCAAG CACCAAGTCA GTTTCCAAAA TTGCCCCTCA 4920 GCTGCTTTAA GTGACTCAGC ACCCTGCCTC AGCTTCAGCA GGCGTAGGCT CACCCTGGGC 4980
GGAGCAAAGT ATGGGCCACG GAGAACTACA GCTACGAAGA CCTGCTGTCG AβTTGAGAAA 5040
AGGGGAGAAT TTATGGTCTG AATTTTCTAA CTGTCCTCTT TCTTGGGTCT AAAGCTCATA 5100
ATACACAAAG GCTTCCAGAC CTGAGCCACA CCCAGGCCCT ATGCTGAACA GGAGACTAAA 5160
CAGAG6CAAA TCAACCCTAG GAAATACTTG CATTCTGCCC TACGGTTAGT ACCAGGACTG 5220
AβGTCATTTC TACTGGAAAA GATTGTGAGA TTGAACTTAT CTGATCGCTT GAGACTCCTA 5280
ATAGGCAGGA GTCAAGGCCA CTAGAAAATT GACAGTTAAG AGCCAAAAGT TTTTAAAATA 5340
TGCTACTCTG AAAAATCTCG TGAAGGCTGT AGGAAAAGGG AGAATCTTCC ATGTTGGTGT 5400
TTTTCCTβTA AAGATCAGTT TGGGGTATGA TATAAGCAGβ TATTAATAAA AATAACACAC 5460
CAAAGAGTTA CGTAAAACAT GTTTTATTAA TTTTGGTCCC CACGTACAGA CATTTTATTT 5520
CTATTTTGAA ATGAGTTATC TATTTTCATA AAAGTAAAAC ACTATTAAAG TGCTGTTTTA 5580
TGTGAAATAA CTTGAATGTT GTTCCTATAA AAAATAGATC ATAACTCATG ATATGTTTGT 5640
AATCATGGTA ATTTAGATTT TTATGAGGAA TGAGTATCTG GAAATATTGT AβCAATACTT 5700
GGTTTAAAAT TTTGGACCTG AβACACTβTG GCTGTCTAAT GTAATCCTTT AAAAATTCTC 5760
TGCATTGTCA GTAAATGTAG TATATTATTG TACAGCTACT CATAATTTTT TAAACTTTAT 5820
GAAGTTATAT TTATCAAATA AAAACTTTCC TATAT 5855
Seq ID NO: C114 DNA Sequence
Nucleic Acid Accession #: XM_087461.1
Coding sequence: 236..1138
11 21 31
CCGGCGCCGG GGGCGGCGGG GAACCCCAAA CGCAACCGββ TCTGGAGGGA TCCCCGCGCC 60
GAGCCAGCCG CCGTCACCGC CTCCGCGCCG CCCCTGCG∞ CTTGGCAGGC GCCCGGCGCG 120
CCCGCACTGC GCCCGGCCGC CGGCTCCCGC GGTCCCACCG TGAGCTCGCC GGCCCGTCGC 180
CCGCTCGCCA TGCAACCGCC GCCGGCCTCG CGCGCGTAGG CGCCCGCCGC AGGCCATGCT 240
GCCCCTGCTC GCCGCGCTCC TGGCCGCCGC CTGCCCGCTG CCGCCCGTCC GCβGCGGGGC 300
CGCGGACGCβ CCCGGCCTCC TCGGGGTGCC CTCCAATGCT TCAGTCAACG CGTCCTCCGC 360
GGCGAGCCCA TCGCCCCGCG GCTGCTGGCC TCGGCGβCCC CCGGGCCCCC CGAGCβCCCβ 420
GGCCCGGAGG AGGCGGCGGC GβCGGCCGCG CCTβTβCAAC ATCAβCGTGC AGCGGCAGAT 480
GCTGAGCTCG CTGCTCGTGC GCTGGGGCCG CCCGCGββGC TTCCAGTβ∞ ACCTACTGCT 540
CTTCTCCACC AACGCGCACG GCCGCGCTTT CTTCGCCGCC GCCTTCCACC GCGTCGGGCC 600
GCCGCTGCTC ATCGAGCACC TGGGGCTGGC GGGGGGCGGC GCGCACCAGG ACCTGCGCCT 660
CTGCGTGGGC TGCCGCTGGG TGCGCGGTCG CCGCACCGβC CGCCTCCGGC CCGCCGCCGC 720
CCCCAGCGCC GCCGCCGCCA CCGCCGGGGC GCCCACCGCG CTGCCAGCCT ACCCCGCGGC 780
CGAGCCGCCC GGGCCGCTGT GGCTGCAGGG CGAGCCGCTG CATTTCTGCT GCCTAGACTT 840
CAGCCTGGAG GA6CTGCAGG GCGAGCCGGG CTGGCG6CTG AACCGTAAGC CCATTGAGTC 900
CACGCTGGTG βCCTGCTTCA TGACCCTGGT CATCGTGGTG TGGAGCGTGG CCGCCCTCAT 960
CTββCCGGTG CCCATCATCG CCGβCTTCCT GCCCAACGGC ATGGAACftGC GCCGGACCAC 1020
CGCCAGCACC ACCGCAGCCA CCCCCGCCGC AGTGCCCCCA GGGACCACCG CAGCCGCCGC 1080
CGCCGCCGCC GCTGCCGCCG CCGCCGCGGC CGTCACTTCG GGGGTGGCGA CCAAGTGACC 1140
CGCTCCGCTC CTCCCTGTGT CCGTCCTGTG TCCGCGCGCG CGGGTGCCTT TCCCGCCGGA 1200
GACTCGGCCG GTGTGCTTCG TGCTGTAGTT ATCGTTAGTT CCTCTTCCCG AGATGGGGCC 1260
GCCGAGAGAC CCCAGCGCCT TTGAAAAGCA AGGTTTGTGC TGCGCTTCCA GTTCCGAAAA 1320 βCAGATGTTT AAGCCCTTGG ACTGAGGGTG GGATCGCAGC TCCGAAGACG GAGAGGAGGG 1380
AAATGGGGCC CTTTCCCCTC TATTGCATCC CCCTGCCCGA CTCCTTCCCC GCACCCACGT 1440
GCCCTAGATT CATGGCAGAA AATGACCAAA TCCTGTGTAT TTGTTTTATA TATTTAATAA 1500
CTGTTTTAAA TGAAAGTTTT AGTAAAAAAA ATACAAAACA AAAAGATTAA ATTGCTATTG 1560
CTGTAGTAAG AGAAGCTCTT TGTATCTGAA CATAβTTGTA TTTGAAATTT GTGGTTTTTT 1620
AATTTATTTA AAATTGGGGG GAGGGCATGG GAAGGATTTA ACACCGATAT ATTGTTACCG 1680
CTGAAAATGA ACTTTATGAA CCTTTTCCAA GTTGATCTAT CCAGTGACGT GGCCTGGTGG 1740
GCGTTTCTTC TTGTACTTAT GTGGTTTTTT GGCTTTTAAT ACAGACATTT TCCTCC 1796
Seq ID NO: C115 DNA Sequence Nucleic Acid Accession ft: XM_051522. Coding sequence: 127..1215
1 11 21 31 41 51 t 1 1 I 1 | 1 |1 I 1
ACAGTTGTTG CAAAGTβCTC AGCACTAAGG GAGCCAGCGC ACAGCACAGC CAGGAAGGCG 60
AGCGAGCCCA GCCAGCCCAG CCAGCCCAGC CAGCCCGGAG GTCATTTGAT TGCCCGCCTC 120
AGAACGATGG ATCTGCATCT CTTCGACTAC TCAGAGCCAG GGAACTTCTC GGACATCAGC 180
TGGCCATGCA ACAGCAGCGA CTGCATCGTG GTGGACACGβ TGATGTGTCC CAACATGCCC 240
AACAAAAGCG TCCTGCTCTA CACGCTCTCC TTCATTTACA TTTTCATCTT CGTCATCGβC 300
ATGATTGCCA ACTCCGTGGT GGTCTGGGTG AATATCCAGG CCAAGACCAC AGGCTATGAC 360
ACGCACTGCT ACATCTTGAA CCTGGCCATT GCCGACCTGT GGGTTβTCCT CACCATCCCA 420
GTCTGGGTGG TCAGTCTCCT GCAGCACAAC CAGTGGCCCA TGGGCGAGCT CACGTGCAAA 480
GTCACACACC TCATCTTCTC CATCAACCTC TTCGGCAGCA TTTTCTTCCT CACGTGCATG 540
AGCGTGGACC GCTACCTCTC CATCACCTAC TTCACCAACA CCCCCAGCAG CAGGAAGAAG 600
ATGGTACGCC GTGTCGTCTG CATCCTGGTG TGGCTGCTGG CCTTCTGCGT GTCTCTGCCT 660 βACACCTACT ACCTGAAGAC CGTCACGTCT GCCTCCAACA ATGAGACCTA CTGCCGGTCC 720
TTCTACCCCG AGCACAGCAT CAAGGA6TGG CTGATCGGCA TGGAGCTGGT CTCCGTTGTC 780
TTGGβCTTTG CCGTTCCCTT CTCCATTATC GCTGTCTTCT ACTTCCTGCT GGCCAGAGCC 840
ATCTCGGCGT CCAGTGACCA GGAGAAβCAC AGCAGCCGGA AGATCATCTT CTCCTACGTG 900
GTGGTCTTCC TTGTCTGCTG GCTGCCCTAC CACGTGGCGG TGCTGCTGGA CATCTTCTCC 960
ATCCTGCACT ACATCCCTTT CACCTGCCGG CTGGAGCACG CCCTCTTCAC GGCCCTGCAT 1020
GTCACACAGT GCCTGTCGCT GGTGCACTGC TGCGTCAACC CTGTCCTCTA CAGCTTCATC 1080
AATCGCAACT ACAGGTACGA GCTGATGAAG GCCTTCATCT TCAAGTACTC GGCCAAAACA 1140
GGGCTCACCA AGCTCATCGA TGCCTCCAGA GTCTCAGAGA CGGAGTACTC TGCCTTGGAG 1200
CAβAβCACCA AATGATCTGC CCTGGAGAGG CTCTGGGACG GβTTTACTTG TTTTTGAACA 1260
GGGTGATGGG CCCTATGGTT TTCTAGAGCA AAGCAAA6TA βCTTCGGGTC TTGAT6CTTG 1320
AGTAGAβTGA AGAGGGGAGC ACGTGCCCCC TGCATCCATT CTCTCTTTCT CTTGATGACG 1380
CAGCTGTCAT TTββCTGTGC GTGCTGACAβ TTTTGCAACA GGCAGAGCTG TGTCGCACAG 1440 CAGTGCTGTG CGTCAGAGCC AGCTGAGGAC AββCTTβCCT GGACTTCTGT AAGATAGGAT 1500
TTTCTGTGTT TCCTGAATTT TTTATATGGT GATTTGTATT TAAATTTTAA GACTTTATTT 1560
TCTCACTATT GGTGTACCTT ATAAATGTAT TTGAAAGTTA AATATATTTT AAATATTGTT 1620
TGGGAGGCAT AGTGCTGACA TATATTCAGA GTGTTGTAGT TTTAAGGTTA GCGTGACTTC 1680
AGTTTTGACT AAGGATGACA CTAATTGTTA GCTGTTTTGA AATTATATAT ATATAAATAT 1740
ATATAAATAT ATAAATATAT GCCAGTCTTG GCTGAAATGT TTTATTTACC ATAGTTTTAT 1800
ATCTGTGTGG TGTTTTGTAC CGβCACGGGA TATGGAACGA AAACTGCTTT GTAATGCAβT 1860
TTGTGACATT AATAGTATTG TAAAGTTACA TTTTAAAATA AACAAAAAAC TGTTCTGGAC 1920
TGCAAATCTG CACACACAAC GAACAGTTGC ATTTCAGAGA GTTCTCTCAA TTTGTAAβTT 1980
ATTTTTTTTT AATAAAGATT TTTGTTTCCT 2010
Seq ID NO : C116 DNA Sequence
Nucleic Acid Accession # : NM.000350 .1
Coding sequence : 82 . .6903
11 21 31 41 51
I I I I I I
CTGGCTCTTA ACGGCGTTTA TGTCCTTTGC TGTCTβAβGG GCCTCAGCTC TGACCAATCT 60
GGTCTTCGTG TGGTCATTAG CATGGGCTTC GTGAGACAβA TACAβCTTTT GCTCTGGAAG 120
AACTGβACCC TGCG6AAAAG GCAAAAGATT CGCTTTGTGG TGGAACTCGT GTGGCCTTTA 180
TCTTTATTTC TGGTCTTGAT CTGGTTAAGG AATGCCAACC CGCTCTACAG CCATCATGAA 240
TGCCATTTCC CCAACAAGGC GATGCCCTCA GCAGGAATGC TGCCGTGGCT CCAGGGGATC 300
TTCTGCAATG TGAACAATCC CTGTTTTCAA AGCCCCACCC CAβGAGAATC TCCTGGAATT 360
GTGTCAAACT ATAACAACTC CATCTTGGCA AGGGTATATC βAGATTTTCA AGAACTCCTC 420
ATGAATGCAC CAGAGAGCCA GCACCTTGGC CβTATTTββA CAβAGCTACA CATCTTGTCC 480
CAATTCATGG ACACCCTCCG GACTCACCCG GAGAGAATTG CAGβAAGAGG AATACβAMA 540
AβGGATATCT TGAAAGATGA AGAAACACTG ACACTATTTC TCATTAAAAA CATCGGCCTG 600
TCTGACTCAG TGGTCTACCT TCTGATCAAC TCTCAAGTCC GTCCAGAGCA GTTCGCTCAT 660
GGAGTCCCGG ACCTGGCGCT GAAGGACATC GCCTGCAGCG AG6CCCTCCT GGAGCGCTTC 720
ATCATCTTCA GCCAGAGACG CGGGGCAAAG ACGGTGCGCT ATGCCCTGTG CTCCCTCTCC 780
CAβββCACCC TACAGTGGAT AGAAβACACT CT6TATGCCA ACGTGGACTT CTTCAAβCTC 840
TTCCGTGTGC TTCCCACACT CCTAGACAβC CβTTCTCAAβ GTATCAATCT GAGATCTTGG 900
GGAGGAATAT TATCTGATAT GTCACCAAGA ATTCAAGAGT TTATCCATCG GCCGAGTATG 960
CAGGACTTGC TGTGGGTGAC CAGGCCCCTC ATGCAGAATG GTβGTCCAGA βACCTTTACA 1020
AAGCTGATGG GCATCCTGTC TGACCTCCTG TβTGGCTACC CCGAGβGAGβ TββCTCTCGG 1080
CTGCTCTCCT TCAACTGGTA TGAAGACAAT AACTATAAGβ CCTTTCTGGG GATTGACTCC 1140
ACAAGGAAGG ATCCTATCTA TTCTTATGAC AGAAGAACAA CATCCTTTTC TAATGCATTG 1200
ATCCAGAGCC TGGAGTCAAA TCCTTTAACC AAAATCGCTT GβAGGβCGGC AAAGCCTTTG 1260
CTGATGGGAA AAATCCTGTA CACTCCTGAT TCACCTGCA6 CACGAAGGAT ACTGAAGAAT 1320
GCCAACTCAA CTTTTGAAGA ACTGGAACAC GTTAGGAAGT TGGTCAAA6C CTGGGAAGAA 1380
GTAGGGCCCC AGATCTGGTA CTTCTTTGAC AACAGCACAC AGATGAACAT GATCAGAGAT 1440
ACCCTGGGGA ACCCAACAGT AAAAGACTTT TTGAATAGβC AβCTTGGTGA AGAAGGTATT 1500
ACTGCTGAAG CCATCCTAAA CTTCCTCTAC AAGGGCCCTC GGGAAAGCCA GGCTGACGAC 1560
ATGGCCAACT TCGACTGGAG GGACATATTT AACATCACTG ATCGCACCCT CCGCCTGGTC 1620
AATCAATACC TGGAGTGCTT GGTCCTGGAT AAGTTTGAAA GCTACAATGA TGAAACTCAG 1680
CTCACCCAAC GTGCCCTCTC TCTACTGGAG GAAAACATGT TCTGGGCCGG AGTGGTATTC 1740
CCTGACATGT ATCCCTGGAC CAGCTCTCTA CCACCCCACG TGAAGTATAA GATCCGAATG 1800
GACATAGACG TGGTGGAGAA AACCAATAAG ATTAAAGACA GGTATTGGGA TTCTGGTCCC 1860
AGAGCTGATC CCGTGGAAGA TTTCCGGTAC ATCTGGGGCG GGTTTGCCTA TCTGCAGGAC 1920
ATGGTTGAAC AGGGGATCAC AAGGAGCCAG GTGCAGGCGG AGGCTCCAGT TGGAATCTAC 1980
CTCCAGCAGA TGCCCTACCC CTGCTTCGTG GACGATTCTT TCATGATCAT CCTGAACCβC 2040
TβTTTCCCTA TCTTCATCGT GCTGGCATGG ATCTACTCTG TCTCCATGAC TGTGAAGAGC 2100
ATCGTCTTGG AβAAGGAGTT G∞ACTβAAβ GAGACCTTGA AAAATCAGGG TβTCTCCAAT 2160
GCAGTGATTT GGTGTACCTG GTTCCTGGAC AGCTTCTCCA TCATGTCGAT GAGCATCTTC 2220
CTCCTGACGA TATTCATCAT GCATGGAAGA ATCCTACATT ACAGCGACCC ATTCATCCTC 2280
TTCCTGTTCT TGTTGGCTTT CTCCACTGCC ACCATCATGC TGTGCTTTCT CCTCAGCACC 2340
TTCTTCTCCA AGGCCAGTCT GGCAGCAGCC TGTAGTGGTG TCATCTATTT CACCCTCTAC 2400
CTGCCACACA TCCTGTGCTT CGCCTGGCAG GACCGCATGA CCGCTGAGCT GAAGAAGGCT 2460
GTGAGCTTAC TGTCTCCGGT GGCATTTGGA TTTGGCACTG AGTACCTGGT TCGCTTTGAA 2520
GAGCAAGGCC TGGGβCTGCA GTGGAGCAAC ATCGGGAACA GTCCCACGGA AβββGACGAA 2580
TTCAGCTTCC TβCTGTCCAT GCA6ATGATG CTCCTTGATG CTGCGTGCTA TGGCTTACTC 2640
GCTTGGTACC TTGATCAGβT GTTTCCAGGA GACTATGGAA CCCCACTTCC TTGGTACTTT 2700
CTTCTACAAG AGTCGTATTG GCTTAGCGGT GAAGGGTGTT CAACCAGAGA AβAAAGAGCC 2760
CTGGAAAAGA CCGAGCCCCT AACAGAGGAA ACGGAGβATC CAGAβCACCC AGAAGGAATA 2820
CACGACTCCT TCTTTGAACG TGAGCATCCA GGGTGGGTTC CTGGGGTATG CGTGAAGAAT 2880
CTGGTAAAGA TTTTTGAGCC CTGTGGCCGβ CCAβCTGTGG ACCGTCTGAA CATCACCTTC 2940
TACGAGAACC AGATCACCGC ATTCCTGGGC CACAATGGAG CTGGGAAAAC CACCACCTTG 3000
TCCATCCTGA CββGTCTGTT GCCACCAACC TCTGGGACTG TGCTCGTTGG βGGAAGGGAC 3060
ATTGAAACCA GCCTGGATGC AGTCCGβCAG AGCCTTGGCA TGTGTCCACA GCACAACATC 3120
CTGTTCCACC ACCTCACGGT G6CTGAGCAC ATGCTβTTCT ATβCCCAGCT GAAAGβAAAβ 3180
TCCCAGGAGG AGβCCCAGCT GGAGATGGAA GCCATGTTGG AGGACACAGG CCTCCACCAC 3240
AAGCGGAATG AAGA6GCTCA GβACCTATCA ββTGGCATGC AGAGAAAGCT GTCGGTTGCC 3300
ATTGCCTTTG TGGGAβATGC CAAGβTGGTβ ATTCTGGACG AACCCACCTC TGGGGTGGAC 3360
CCTTACTCGA GACGCTCAAT CTGGGATCTG CTCCTGAAGT ATCGCTCAGG CAGAACCATC 3420
ATCATGCCCA CTCACCACAT GGACGAGGCC GACCACCAAG GGGACCGCAT TGCCATCATT 3480
GCCCAGGGAA GGCTCTACTG CTCAGGCACC CCACTCTTCC TGAAGAACTG CTTTGβCACA 3540 GGCTTGTACT TAACCTTGGT GCGCAAGATG AAAAACATCC AGAGCCAAAG GAAAGGCAGT 3600 GAGGGGACCT GCAGCTGCTC GTCTAAGGGT TTCTCCACCA CGTGTCCAGC CCACGTCGAT 3660 GACCTAACTC CAGAACAAGT CCTGβATβGG GATGTAAATG AGCTGATGGA TGTAGTTCTC 3720 CACCATβTTC CAGAGGCAAA GCTGGTGGAG TGCATTGGTC AAGAACTTAT CTTCCTTCTT 3780 CCAAATAAGA ACTTCAAGCA CAGAGCATAT GCCAGCCTTT TCAGAGAGCT GGAGGAGACG 3840 CTGGCTGACC TTGGTCTCAG CAGTTTTβGA ATTTCTGACA CTCCCCTGGA AGAGATTTTT 3900 CTGAAGβTCA CGGAGGATTC TGATTCAGGA CCTCTGTTTG CGGGTGGCGC TCAGCAGAAA 3960 AGAGAAAACG TCAACCCCCG ACACCCCTGC TTGGGTCCCA GAGAGAAGGC TGβACAGACA 4020 CCCCAGGACT CCAATGTCTG CTCCCCAGGG GCGGCGGCTG CTCACCCAGA GGGCCAGCCT 4080
CCCCCAGAGC CAGAGTGCCC AGGCCCGCAG CTCAACACGG GGACACAGCT GGTCCTCCAβ 4140
CATGTGCAGG CGCTGCTGGT CAAGAGATTC CAACACACCA TCCGCAGCCA CAAGGACTTC 4200
CTGGCGCAGA TCGTGCTCCC GGCTACCTTT GTGTTTTTGG CTCTGATGCT TTCTATTGTT 4260
ATCCTTCCTT TTGGCGAATA CCCCGCTTTG ACCCTTCACC CCTGGATATA TGGGCAGCAG 4320
TACACCTTCT TCAGCATGβA TGAACCAGGC AGTGAGCAGT TCACGGTACT TGCAβACGTC 4380
CTCCTGAATA AGCCAGGCTT TGGCAACCGC TGCCTGAAGG AAGGGTGGCT TCCGGAGTAC 4440
CCCTGTGGCA ACTCAACACC CTGGAAGACT CCTTCTGTGT CCCCAAACAT CACCCAGCTG 4500
TTCCAGAAGC AGAAATGGAC ACAGGTCAAC CCTTCACCAT CCTGCAGGTG CAGCACCAGG 4560
GAGAAGCTCA CCATGCTGCC AGAGTGCCCC GAGGGTGCCG GGGGCCTCCC GCCCCCCCAG 4620
AGAACACAGC GCAGCACGGA AATTCTACAA GACCTGACGG ACAGGAACAT CTCCGACTTC 4680
TTGGTAAAAA CGTATCCTGC TCTTATAAGA AGCAGCTTAA AGAβCAAATT CTGGGTCAAT 4740
GAACAGAGGT ATGGAGGAAT TTCCATTGGA GGAAAGCTCC CAGTCβTCCC CATCACGGGG 4800
GAAGCACTTG TTGGGTTTTT AAGCGACCTT GGCCββATCA TGAATGTGAG CGGGGGCCCT 4860
ATCACTAGAG AGGCCTCTAA AGAAATACCT GATTTCCTTA AACATCTAGA AACTGAAGAC 4920
AACATTAAGG TGTGGTTTAA TAACAAAGGC TGGCATGCCC TGGTCAGCTT TCTCAATGTG 4980
GCCCACAACG CCATCTTACG GGCCAGCCTG CCTAAGGACA βGAβCCCCGA GGAGTATββA 5040
ATCACCGTCA TTAGCCAACC CCTGAACCTG ACCAAβGAGC AGCTCTCAGA GATTACAGTG 5100
CTGACCACTT CAGTGGAT6C TGTGGTTGCC ATCTGCGTGA TTTTCTCCAT GTCCTTCGTC 5160
CCAGCCAGCT TTGTCCTTTA TTTGATCCAG GAGCGGGTGA ACAAATCCAA GCACCTCCAG 5220
TTTATCAGTG GAGTGAGCCC CACCACCTAC TGGGTGACCA ACTTCCTCTβ GGACATCATG 5280
AATTATTCCG TGAGTGCTβG GCTβGTGGTG GGCATCTTCA TCGGGTTTCA GAAGAAAGCC 5340
TACACTTCTC CAGAAAACCT TCCTGCCCTT GTGGCACTGC TCCTGCTGTA TGGATGGGCG 5400
GTCATTCCCA TGATGTACCC AGCATCCTTC CTGTTTGATG TCCCCAGCAC AGCCTATGTG 5460
GCTTTATCTT GTGCTAATCT GTTCATCGGC ATCAACACCA GTGCTATTAC CTTCATCTTG 5520
GAATTATTTG ATAATAACCG GACGCTGCTC AGGTTCAACG CCGTGCTGAG GAAGCTGCTC 5580
ATTGTCTTCC CCCACTTCTG CCTGGGCCGG GGCCTCATTG ACCTTGCACT GAGCCAGGCT 5640
GTGACAGATG TCTATGCCCG GTTTGGTGAG GAGCACTCTG CAAATCCGTT CCACTGGGAC 5700
CTGATTGβGA AGAACCTGTT TGCCATGGTG GTGGAAGGGG TGGTGTACTT CCTCCTGACC 5760
CTGCTGGTCC AGCGCCACTT CTTCCTCTCC CAATGGATTG CCGAGCCCAC TAAGGAGCCC 5820
ATTGTTGATG AAGATGATGA TGTGGCTGAA GAAAGACAAA GAATTATTAC TGGTGGAAAT 5880
AAAACTGACA TCTTAAGGCT ACATGAACTA ACCAAβATTT ATCTGGβCAC CTCCACCCCA 5940
GCAGTGGACA GGCTGTGTGT CGGAGTTCGC CCTGGAGAGT GCTTTGGCCT CCTGGGAGTG 6000
AATGGTGCCG GCAAAACAAC CACATTCAAG ATGCTCACTG GGGACACCAC AGTGACCTCA 6060
GGGGATGCCA CCGTAβCAGG CAAGAGTATT TTAACCAATA TTTCTGAAGT CCATCAAAAT 6120
ATGGGCTACT GTCCTCAGTT TGATGCAATC GATGAGCTGC TCACAGGACG AGAACATCTT 6180
TACCTTTATG CCCGGCTTCG AGGTGTACCA GCAGAAGAAA TCGAAAAGGT TGCAAACTGG 6240
AGTATTAAGA GCCTGGGCCT GACTGTCTAC GCCGACTGCC TGGCTGGCAC GTACAGTββG 6300
GGCAACAAGC GGAAACTCTC CACAGCCATC GCACTCATTG GCTGCCCACC GCTGGTGCTG 6360
CTGGATGAGC CCACCACAGG GATGGACCCC CAGGCACGCC GCATGCTGTG GAACGTCATC 6420
GTGAβCATCA TCAGAAAAGG GAGGGCTGTG GTCCTCACAT CCCACAGCAT GGAAGAATGT 6480
GAGGCACTGT GTACCCGGCT GGCCATCATG GTAAAGGGCG CCTTTCGATG TATGGGCACC 6540
ATTCAGCATC TCAAGTCCAA ATTTGGAGAT GGCTATATCG TCACAATGAA GATCAAATCC 6600
CCGAAGGACG ACCTGCTTCC TGACCTGAAC CCTGTGGAGC AGTTCTTCCA GGGGAACTTC 6660
CCAGGCAGTG TGCAGAGGGA GAGGCACTAC AACATGCTCC AGTTCCAGGT CTCCTCCTCC 6720
TCCCTGGCGA GGATCTTCCA GCTCCTCCTC TCCCACAAGG ACACCCTGCT CATCGAGGAG 6780
TACTCAGTCA CACAGACCAC ACTGGACCAG GTGTTTGTAA ATTTTGCTAA ACAGCAGACT 6840
GAAAGTCATG ACCTCCCTCT GCACCCTCGA GCTGCTGGAG CCAGTCGACA AGCCCAGGAC 6900
TGATCTTTCA CACCGCTCGT TCCTGCAGCC AGAAAGGAAC TCTGGGCAGC TGGAGGCGCA 6960
GGAGCCTGTG CCCATATGGT CATCCAAATG GACTGGCCCA GCGTAAATGA CCCCACTGCA 7020
GCAGAAAACA AACACACGAG GAGCATGCAG CCAATTCAGA AAGAGGTCTT TCAGAAGGAA 7080
AC∞AAACTG ACTTGCTCAC CTGGAACACC TGATGGTGAA ACCAAACAAA TACAAAATCC 7140
TTCTCCAGAC CCCAGAACTA GAAACCCCGG GCCATCCCAC TAGCAGCTTT GGCCTCCATA 7200
TTGCTCTCAT TTCAAGCAGA TCTGCTTTTC TGCATGTTTG TCTGTGTGTC TGCGTTGTβT 7260
GTGATTTTCA TGGAAAAATA AAAT6CAAAT GCACTCATCA CAAAAAAAAA AAAAAAAA 7318
Seq ID NO: C117 DNA Sequence
Nucleic Acid Accession ff: NM_006671.2
Coding sequence: 138..1820
11 21 31 51
GGCACGAGGC TGGTGTTTAG CAACTCCGAC CACCTGCCTβ CTGAGGGGCT AGAGCCCTCA 60
GCCCAGACCC TGTGCCCCCG GCCGGGCTCT CATGCGTGGA ATGGTGCTGT GCCCCTTGCC 120
AGCAGGCCAG GCTCACCATG GTGCCGCATG CCATCTTGGC ACGGGGGAGG GACGTGTGCA 180
GGCGGAATGG ACTCCTCATC CTGTCTGTGC TβTCTβTCAT CGTGGGCTGC CTCCTCGGCT 240
TCTTCTTGAG GACCCGGCGC CTCTCACCAC AGGAAATTAG TTACTTCCAG TTCCCTGGAG 300
AGCTCCTGAT GAGGATGCTG AAGATGATGA TCCTGCCACT GGTGGTCTCC AGCTTGATGT 360
CCGGACTTGC CTCCCTGGAT GCCAAGACCT CTAGCCGCCT GGGCGTCCTC ACCGTGGCGT 420
ACTACCTGTG GACCACCTTC ATGGCTCTCA TCGTGGGCAT CTTCATGβTC TCCATCATCC 480
ACCCAGGCAG CGCGGCCCAβ AAGGAGACCA CGGAGCAGAG TGGGAAGCCC ATCATGAGCT 540
CAGCCGATGC CCTGTTGGAC CTCATCCGGA ACATGTTCCC AGCCAACCTA GTAGAAGCCA 600
CATTCAAACA GTACCGCACC AAGACCACCC CAGTTGTCAA GTCCCCCAAG GTGGCACCAG 660
AGGAGGCCCC TCCTCGGCGG ATCCTCATCT ACGGGGTCCA ββAGGAβAAT GGCTCCCATG 720
TGCAGAACTT CGCCCTGGAC CTGACCCCGC CGCCCGAGGT CGTTTACAAG TCAGAGCCGG 780
GCACCAGCGA TGGCATGAAT GTGCTGGGCA TCGTCTTCTT CTCTGCCACC ATGGGCATCA 840
TGCTGGβCCG CATGGGTGAC AGCGGGGCCC CCCTGGTCAG CTTCTGCCAG TGCCTCAATG 900
ACTCGGTCAT GAAGATCGTG GGGGTGGCTG TGTGGTATTT CCCCTTCGGC ATTGTGTTCC 960
TCATTGCGGG TAAGATCCTG GAGATGGACG ACCCCAGGGC CGTCGGCAAG AAGCTGGGCT 1020
TCTACTCAGT CACCGTGGTG TGCGGGCTGG TβCTCCACβG GCTCTTTATC CTGCCCCTGC 1080
TCTACTTCTT CATCACCAAG AAGAATCCCA TCGTCTTCAT CCGCGGCATC CTGCAGGCTC 1140
TGCTCATCGC GCTGGCCACC TCCTCCAGCT CAGCCACACT GCCCATCACC TTCAAGTGCC 1200
TGCTGGAGAA CAACCACATC GACCGGCGCA TCGCTCGCTT CGTGCTGCCC GTGGGTGCCA 1260
CCATCAACAT GGACGGCACT GCGCTCTACG AGGCTGTGGC CGCCATCTTC ATCGCCCAGG 1320 TCAACAACTA CGAGCTGGAC TTTGGCCAGA TCATCACCAT CAGTATCACA GCCACTGCAG 1380
CCAGCATTGG GGCAGCTGGC ATCCCCCAGG CCGGCCTCGT CACCATGGTC ATCGTGCTCA 1440
CCTCCGTGGG ACTGCCCACC GATGACATCA CCCTCATCAT TβCCGTTGAC TGββCTCTGG 1500
ACCGTTTCCG CACCATGATT AACGTGCTβG GTGATGCGCT GGCAGCGGGG ATCATGGCCC 1560
ATATATGTCG GAAGGATTTT GCCCGGGACA CAGGCACCGA GAAACTβCTG CCCTGCGAGA 1620
CCAAGCCAGT GAGCCTCCAG GAGATCGTGG CAGCCCAGCA GAATGGCTGT GTGAAGAβTβ 1680
TAGCCGAGGC CTCCGAGCTC ACCCTGGGCC CCACCTGCCC CCACCACGTC CCCGTTCAAG 1740
TGGAGCGGGA TGAGGAGCTG CCCGCTGCGA GTCTGAACCA CTGCACCATC CAGATCAGCG 1800
AGCTGGAGAC CAATGTCTGA GCCTGCGGAG CTGCAGGGGC AGGCGAGGCC TCCAGGGGCA 1860
GGGTCCTGAG GCAGGAACTC GACTCTCCAA CCCTCCTGAG CAGCCGGCAG GGGCCAGGAT 1920
CACACATTCT TCTCACCCTT GAβAGGCTGG AATTAACCCC GCTTGACGGA AAATGTATCT 1980
CAGAGAAGGG AAAGGCTGCA TGGGββAGCC CCATCCAGGG AGTGATGGGC CCGGCATTGC 2040
CTGAGGCCCC GCTGTGACAβ TTTCCCCGGT GTβAGCCCGG TGAGGGCGGC AGGCAGGGGT 2100
TATCCGGCCC CACTTTCTGG ATGACAGACT TGAGGCTCTG AGAGCTGAAA ACACTTGTCC 2160
AAGGTCTCAC GTTAAGβTCA AGACACTAAC TCAAATCTTT CAAGCCCCGC CTCTCCTCTT 2220
GβAGGACAGG GCAGCCTGCA GCTGTGTCCA GGCCCAGGCC CCACCCCATA ACAGGTGGCC 2280
TCAGCCACAC AGTTCTCCCC AAGGGGAGCA GCCCAGGGCC AAGCCCCGCT GCCTTCCCCA 2340
GGCCACAGTG CGTCCAGTCT CCTGTCCTGC CACGTGTCTT TTβCAAAβCT CCTTGGATGT 2400
GGAGACAGAT GTCTTTACTA GAGCTGAAAG GCCCCCTTGA CACATCCAGG CCAACCTCCC 2460
ATGGAATAGG TAGGCAAGCC AGGACTCCGG GAAGGAGGTG CAGCCAGGAT GCTCTGGTGG 2520
AGCTGCCGAT GGGGCCCTGβ TGTCAGAACT CCCCAAAGGC CTGTGCGTCC AAGTGGAGTC 2580
AGGTTTTCTA TTCCTTTCTG TGTTTGCAAA TTCAGTGTTA ACTAAATAAA GGTATTTTGT 2640
TTTTCAAAAA AAAAAAAAAA AAA 2663
Seq ID NO: C118 DNA Sequence Nucleic Acid Accession #: NM_005689 Coding sequence: 278..2806
1 11 21 31 41 51
I I I I I I
GGGCCTGCAG TTGGCAGAAG GGTCCCGGGC CCAGAGCCAG CGGGGCCGTG CTGAGACGGC 60
GTACGTGCCC TGCGTGAGTG CGTGβCGGCG GCGCGTGCGC TAGGGGAGTG GβCββTβAGG 120
CCTGGTCCAC GTGCGTCCCT TCCCGGGACC CCCGCACCTT ββCGCCCAGC GGCTACGTGA 180
GCCAAGGCAC CCGβATGTCC GCGCCCCTCT CCGAGTGACA AGTCCCGGCC TCCGGTCCCG 240
CAGTGCCCGC AGCCTCGGCC GGCGTCCACG CATTGCCATG GTβACTGTGG GCAACTACTG 300
CGAGGCCGAA GGGCCCGTGG GTCCGGCCTG GATGCAGβAT GGCCTGAGTC CCTGCTTCTT 360
CTTCACGCTC GTGCCCTCGA CGCGGATGGC TCTAGGGACT CTGGCCTTGG TGCTGGCTCT 420
TCCCTGCACA CGCCGGGAGC GGCCCGCTGG TGCTGATTCG CTGTCTTGGG GGGCCGGCCC 480
TCGCATCTCT CCCTACGTGC TGCAGCTGCT TCTGGCCACA CTTCAGGCGG CGCTGCCCCT 540
GGCCGGCCT6 GCTGGCCGGG TGGGCACTGC CCGGGGββCC CCACTGCCAA GCTATCTACT 600
TCTGGCCTCC GTGCTGGAGA GTCTGGCCGG CGCCTGTββC CTGTGGCTGC TTGTCGTGGA 660
GCGGAGCCAβ GCACGGCAGC GTCTGGCAAT GGGCATCTGG ATCAAGTTCA GGCACAGCCC 720
TGGTCTCCTG CTCCTCTGGA CTGTβGCGTT TGCAGCTGAβ AACTTGGCCC TGGTGTCTTG 780
GAACAGCCCA CAGTGGTGGT GGGCAAGGGC AGACTTGGGC CAACAGGTTC AGTTTAGCCT 840
GTGGGTGCTG CGGTATGTGG TCTCTGGAGG GCTGTTTGTC CTGGGTCTCT GGGCCCCTGG 900
ACTTCGTCCC CAGTCCTATA CATTGCAGGT TCATGAAGAG GACCAAGATG TGGAAAGGAG 960
CCAGGTTCGG TCAGCAGCCC AACAGTCTAC CTGGCGAGAT TTTGGCAGGA AGCTCCGCCT 1020
CCTGAGTGGC TACCTGTGGC CTCGAGGGAG TCCAGCTCTG CAGCTGGTGG TGCTCATCTG 1080
CCTGGβGCTC ATGGGTTTGG AACGGGCACT CAATGTGTTG GTGCCTATAT TCTATAGGAA 1140
CATTGTGAAC TTβCTGACTG AGAAβGCACC TTGGAACTCT CTGGCCTGGA CTGTTACCAG 1200
TTACGTCTTC CTCAAGTTCC TCCAGGGGGG TGGCACTGGC AGTACAGGCT TCGTβAGCAA 1260
CCTGCGCACC TTCCTGTGGA TCCGβGTGCA GCAGTTCACG TCTCGGCGGG TGGAGCTGCT 1320
CATCTTCTCC CACCTGCACG AGCTCTCACT GCGCTGGCAC CTGGGGCGCC GCACAGGGGA 1380
GGTGCTGCGG ATCGCGGATC GGGGCACATC CAGTGTCACA GGGCTβCTCA GCTACCTGGT 1440
GTTCAATβTC ATCCCCACGC TGGCCGACAT CATCATTGGC ATCATCTACT TCAGCATGTT 1500
CTTCAACecC TββTTTGGCC TCATTGTGTT CCTGTGCATG AGTCTTTACC TCACCCTGAC 1560
CATTGTGGTC ACTGAGTGGA GAACCAAGTT TCGTCGTGCT ATGAACACAC AβGAGAACGC 1620
TACCCGGGCA CGAβCAGTGG ACTCTCTGCT AAACTTCGAG ACGGTGAAGT ATTACAACGC 1680
CGAGAGTTAC βAAGTGGAAC GCTATCGAGA GGCCATCATC AAATATCAGG GTTTGGAGTG 1740
GAAGTCGAGC GCTTCACTGG TTTTACTAAA TCAGACCCAG AACCTGGTGA TTGGGCTCGG 1800
GCTCCTCGCC GGCTCCCTGC TTTGCGCATA CTTTGTCACT GAGCAGAAGC TACAGGTTGG 1860
GGACTATGTG CTCTTTGGCA CCTACATTAT CCAGCTGTAC ATGCCCCTCA ATTGGTTTGG 1920
CACCTACTAC AGGATGATCC AGACCAACTT CATTGACATG GAGAACATGT TTGACTTGCT 1980
GAAAGAGβAβ ACAGAAGTGA AGGACCTTCC TGGAGGAGGG CCCCTTCGCT TTCAGAAGGβ 2040
CCGTATTGAG TTTGAGAACβ TGCACTTCAG CTATGCCGAT GGGCβGGAGA CTCTGCAGGA 2100
CGTβTCTTTC ACTGTGATGC CTGGACAGAC ACTTGCCCTG GTGGGCCCAT CTGGGGCAGG 2160
GAAGAGCACA ATTTTβCGCC TGCTGTTTCβ CTTCTACGAC ATCAGCTCTG GCTGCATCCG 2220
AATAGATGGG CAGGACATTT CACAGGTGAC CCAGGCCTCT CTCCGGTCTC ACATTGGAGT 2280
TGTGCCCCAA GACACTGTCC TCTTTAATGA CACCATCGCC GACAATATCC GTTACGGCCG 2340
TGTCACAGCT GGGAATGATG AGGTGGAGGC TGCTGCTCAG GCTGCAGGCA TCCATGATGC 2400
CATTATGGCT TTCCCTGAAG GGTACAGGAC ACAGGTGGGC GAGCGGGGAC TGAAGCTGAG 2460
CGGCGGGβAG AAβCAβCGCG TCGCCATTGC CCGCACCATC CTCAAGGCTC CGGGCATCAT 2520
TCTGCTGGAT GAGGCAACGT CAGCGCTGGA TACATCTAAT GAGAGGGCCA TCCAGGCTTC 2580
TCTGGCCAAA GTCTGTβCCA ACCβCACCAC CATCGTAGTG GCACACAGGC TCTCAACTGT 2640
GGTCAATGCT GACCAGATCC TCGTCATCAA GGATGGCTGC ATCGTβGAGA GGGGACGACA 2700
CGAGGCTCTG TTGTCCCGAG GTGGGGTGTA TGCTGACATG TGGCAGCTGC AGCAGGGACA 2760
GGAAGAAACC TCTGAAGACA CTAAGCCTCA GACCATGGAA CGGTGACAAA AGTTTGGCCA 2820
CTTCCCTCTC AAAGACTAAC CCAGAAGGGA ATAAGATGTβ TCTCCTTTCC CTGGCTTATT 2880
TCATCCTGGT CTTGGGGTAT GGTGCTAGCT ATGGTAAGGG AAAβGGACCT TTCCβAAAAA 2940
CATCTTTTGG GGAAATAAAA ATGTGGACTG TGAAAAAAAA AAAAAAAAAA AAA 2993
Seq ID NO : C119 DNA Sequence Nucleic Acid Accession ft : NM_000676 Coding sequence : 333 . .1331 1 11 21 31 41 51
1 1 I 1 1 | 1 | 1 | 1 βGGCAATTTG TTAGTTATCC GCCGCCACCA AGACGCGGCA CGGCGCCTGG ACCGGAGGGG 60
CCCCGCGCGG GCGCGAACTT TGGGCTCGGG CGAβTGGGTG GTGCTCCGCC CAGCCCGAGA 120
CGGGCGGGCG CGCGGGCCAA TGGGTGCCGC CTCTTGGCCG CGGGGGGCCC CGACCCGTGβ 180
GTCCCGGCCA CCAGCGCCCC AGCCCCGAGG CTCAGAAGCG GCAGGCGGAG GCGCGGTCCG 240
GGCGCTATGG CCATGCCCGG CGGβTCTCAC GCGGCTGCCC CTCGCCCGGC GCGCCTTCGG 300
TAGGGGGCGC CCGGGGCCCA GCTGGCCCGG CCATGCTGCT GGAGACACAG GACGCβCTGT 360
ACGTGGCGCT GGAGCTGGTC ATCGCCGCGC TTTCGGTGGC GGGCAACGTG CTGGTGTGCG 420
GCGCGCTGGG CACGGCGAAC ACTCTGGAGA CGCCCACCAA CTACTTCCTG GTGTCCCTGG 480
CTGCGGCCGA CGTGGCCGTG GGGCTCTTCG CCATCCCCTT TGCCATCACC ATCAGCCTGG 540
GCTTCTGCAC TGACTTCTAC GGCTGCCTCT TCCTCGCCTG CTTCGTGCTG GTGCTCACGC 600
AGAGCTCCAT CTTCAGCCTT CTGGCCGTGG CAGTCGACAG ATACCTGGCC ATCTGTCTCC 660
CGCTCAGGTA TAAAAGTTTG GTCACGGGGA CCCGAGCAAG AGGGGTCATT GCTGTCCTCT 720
GGGTCCTTGC CTTTGGCATC GGATTGACTC CATTCCTGGG GTGGAACAGT AAAβACAGTG 780
CCACCAACAA CTGCACAGAA CCCTGGGATG GAACCACGAA TGAAAGCTGC TGCCTTGTGA 840
AGTβTCTCTT TGAGAATGTG GTCCCCATGA GCTACATGGT ATATTTCAAT TTCTTTGGCT 900
GTGTTCTGCC CCCACTGCTT ATAATGCTGG TGATCTACAT TAAGATCTTC CTGβTGGCCT 960
GCAGGCAGCT TCAGCGCACT GAGCTGATGG ACCACTCGAG GACCACCCTC CAGCGβGAGA 1020
TCCATGCAGC CAAGTCACTG GCCATGATTG TGGGGATTTT TGCCCTGTGC TGGTTACCTG 1080
TGCATGCTGT TAACTGTGTC ACTCTTTTCC AGCCAGCTCA GGGTAAAAAT AAGCCCAAGT 1140
GGGCAATGAA TATGGCCATT CTTCTGTCAC ATGCCAATTC AGTTGTCAAT CCCATTGTCT 1200
ATGCTTACCG GAACCGAGAC TTCCGCTACA CTTTTCACAA AATTATCTCC AGGTATCTTC 1260
TCTGCCAAGC AGATGTCAAG AGTGGGAATG GTCAGGCTGG GGTACAGCCT GCTCTCGGTG 1320
TGGGCCTATG ATCTAGβCTC TCβCCTCTTC CAGGAGAAGA TACAAATCCA CAAβAAACAA 1380
AGAGGACACG βCTGGTTTTC ATTGTGAAAG ATAGCTACAC CTCACAAGGA AATGGACTGC 1440
CTCTCTTGAG CACTTCCCTG GAGCTACCAC GTATCTAGCT AATATGTATG TGTCAGTAGT 1500
AGGCTCCAAG GATTGACAAA TATATTTATG ATCTATTCAG CTGCTTTTAC TGTGTGGATT 1560
ATGCCAACAG CTTGAATGGA TTCTAACAGA CTCTTTTGTT TTTAAAAGTC TGCCTTGTTT 1620
ATGGTGGAAA ATTACTGAAA CTATTTTACT GTGAAACAGT GTGAACTATT ATAATGCAAA 1680
TACTTTTTAA CTTAGAβGCA ATGβAAAAAT AAAAGTTGAC TGTACTAAAA ATG 1733
Seq ID NO: C120 DNA Sequence Nucleic Acid Accession #: NM.052932 Coding sequence : 217..786
1 11 21 31
I I
CCCAGCCCGG CCCCGCCGCC C ICGGCTGCGC AICGCGACGCC CCCTCCAGGC cccβCTccTβ 60 CGCCCTATTT GGTCATTCGG GGGGCAAGCG GCGGGAGGGG AAACGTGCGC GGCCGAAGGG 120 GAAGCGGAGC CGGCGCCGGC TGCGCAGAGG AGCCGCTCTC GCCGCCGCCA CCTCGGCTGβ 180 GAGCCCACGA GGCTGCCGCA TCCTGCCCTC GGAACAATGG GACTCGGCGC GCGAGGTGCT 240 TGGβCCGCGC TGCTCCTGGG GACGCTGCAG GTGCTAGCGC TGCTGGGGβC CGCCCATGAA 300 AGCGCAGCCA TGGCGGAGAC TCTCCAACAT GTGCCTTCTG ACCATACAAA TGAAACTTCC 360 AACAGTACTG TGAAACCACC AACTTCAGTT GCCTCAGACT CCAGTAATAC AACGGTCACC 420 ACCATGAAAC CTACAGCGGC ATCTAATACA ACAACACCAG GGATGGTCTC AACAAATATG 480 ACTTCTACCA CCTTAAAGTC TACACCCAAA ACAACAAGTG TTTCACA6AA CACATCTCAG 540 ATATCAACAT CCACAATGAC CGTAACCCAC AATAGTTCAG TGACATCT6C TβCTTCATCA 600 GTAACAATCA CAACAACTAT GCATTCTGAA GCAAAGAAAG GATCAAAATT TGATACTGGG 660 AGCTTTGTTG GTGGTATTGT ATTAACGCTG GGAGTTTTAT CTATTCTTTA CATTGGATGC 720 AAAATGTATT ACTCAAGAAG AGGCATTCGG TATCGAACCA TAGATGAACA TGATGCCATC 780 ATTTAAGGAA ATCCATGGAC CAAGGATGGA ATACAGATTG ATGCTGCCCT ATCAATTAAT 840 TTTGGTTTAT TAATAGTTTA AAACAATATT CTCTTTTTGA AAATAβTATA AACAGGCCAT 900 GCATATAATG TACAGTGTAT TACGTAAATA TGTAAAGATT CTTCAAGGTA ACAAGGGTTT 960 GGGTTTTGAA ATAAACATCT GGATCTTATA GACCGTTCAT ACAATGGTTT TAGCAAGTTC 1020 ATAGTAAGAC AAACAAGTCC TATCTTTTTT TTTTTGGCTG GGGTGGGGGC ATTGGTCACA 1080 TATGACCAGT AATTGAAAGA CGTCATCACT GAAAGACAGA ATGCCATCTG GGCATACAAA 1140 TAAGAAGTTT GTCACAGCAC TCAGGATTTT GGGTATCTTT TGTAGCTCAC ATAAAGAACT 1200 TCAGTGCTTT TCAGAGCTGG ATATATCTTA ATTACTAATG CCACACAGAA ATTATACAAT 1260 CAAACTAGAT CTGAAGCATA ATTTAAGAAA AAGATCAACA TTTTTTGTGC TTTAAACTGT 1320 AGTAGTTGGT CTAGAAACAA AATACTCCAA GAAAAAGAAA ATTTTCAAAT AAAACCCAAA 1380 ATAATAGCTT TGCTTAGCCC TGTTAGGGAT CCATTGGAGC ATTAAGGAβC ACATATTTTT 1440 ATTAACTTCT TTTGAGCTTT CAATGTTGAT GTAATTTTTG TTCTCTGTGT AATTTAGGTA 1500 AACTCCAGTG TTTAACATAA TAATGTTTTA AAGACTTAGT TGTCAGTATT AAATAATCCT 1560 GGCATTATAG GGAAAAAACC TCCTAGAAGT TAGATTATTT GCTACTGTGA GAATATTGTC 1620 ACCACTGGAA GTTACTTTAG TTCATTTAAT TTTAATTTTA TATTTTGTGA ATATTTTAAG 1680 AACTGTAGAG CTGCTTTCAA TATCTAGAAA TTTTTAATTG AGTGTAAACA CACCTAACTT 1740 TAAGAAAAAG AACCGCTTGT ATGATTTTCA AAAGAACATT TAGAATTCTA TAGAGTCAAA 1800 ACTATAGCGT AATGCTGTGT TTATTAAGCC AGGGATTGTG GGACTTCCCC CAGGCAACTA 1860 AACCTGCAGG ATGAAAATGC TATATTTTCT TTCATGCACT GTCGATATTA CTCAGATTTG 1920 GG6AAATGAC ATTTTTATAC TAAAACAAAC ACCAAAATAT TTTAGAATAA ATTCTTAGAA 1980 AGTTTTGAGA GGAATTTTTA GAGAGGACAT TTCCTCCTTC CTGATTTQ3A TATTCCCTCA 2040 AATCCCTCCT CTTACTCCAT GCTGAAGGAG AAGTACTCTC AGATGCATTA TGTTAATGGA 2100 GAGAAAAAGC ACAGTATTGT AGAGACACCA ATATTAGCTA ATGTATTTTG GAGTGTTTTC 2160 CATTTTACAG TTTATATTCC AGCACTCAAA ACTCAGGGTC AAGTTTTAAC AAAAGAGGTA 2220 TGTAGTCACA GTAAATACTA AGATGGCATT TCTATCTCAG AGGGCCAAAG TβAATCACAC 2280 CAGTTTCTGA AGGTCCTAAA AATAGCTCAG ATGTCCTAAT GAACATGCAC CTACATTTAA 2340 TAGGAGTACA ATAAAACTGT TGTCAGCTTT TGTTTTACAG AGAACGCTAG ATATTAAGAA 2400 TTTTGAAATG GATCATTTCT ACTTGCTGTG CATTTTAACC AATAATCTGA TGAATATAGA 2460 AAAAAATβAT CCAAAATATG GATATGATTG GATGTATGTA ACACATACAT GβAGTATGGA 2520 GGAAATTTTC TGAAAAATAC ATTTAGATTA GTTTAGTTTG AAGGAGAGGT GGGCTGATGG 2580 CTGAGTTGTA TGTTACTAAC TTGGCCCTGA CTGGTTGTGC AACCATTGCT TCATTTCTTT 2640 GCAAAATGTA GTTAAGATAT ACTTTATTCT AATGAAGGCC TTTTAAATTT GTCCACTGCA 2700 TTCTTGGTAT TTCACTACTT CAAGTCAGTC AGAACTTCGT AGACCGACCT GAAGTTTCTT 2760
TTTGAATACT TβTTTCTTTA GCACTTTGAA GATAGAAAAA CCACTTTTTA AGTACTAAGT 2820
CATCATTTGC CTTGAAAGTT TCCTCTGCAT TGGGTTTGAA CTAGTTTAGT TATGTCTTTT 2880
TCTCTGTATG TAAGTAGTAT AATTTGTTAC TTTCAAATAC CCGTACTTTG AATGTAGβTT 2940
TTTTTGTTGT TGTTATCTAT AAAAATTGAG GGAAATGGTT ATGCAAAAAA ATATTTT6CT 3000
TTGGACCATA TTTCTTAAGC ATAAAAAAAT GCTCAβTTTT GCTTGCATTC CTTGAGAATG 3060
TATTTATCTG AAGATCAAAA CAAACAATCC AGATGTATAA GTACTAGGCA GAAGCCAATT 3120
TTAAAATTTC CTTGAATAAT CCATGAAAGG AATAATTCAA ATACAβATAA ACAGAGTTGG 3180
CAGTATATTA TAGTGATAAT TTTGTATTTT CAAMAAAAAA AAAGTTAAAC TCTTCTTTTC 3240
TTTTTATTAT AATGACCAGC TTTTGGTATT TCATTGTTAC CAAGTTCTAT TTTTAGATAA 3300
AATTGTTCTC CTTCTAAAAA AAAAAAAAAA AAAAAAAA 3338
Seq ID NO : C121 DNA Sequence Nucleic Acid Accession ft : NM_004195 Coding sequence : 1 . .726
11 21 31
ATGGCACAGC ACGGGGCGAT GGGCGCGTTT CGGGCCCTGT GCGGCCTGGC GCTGCT6TGC 60
GCGCTCAGCC TGGGTCAGCG CCCCACCGGG GGTCCCGGGT βceecccTGG GCGCCTCCTG 120
CTTGβGACGG GAACGGACGC GCGCTGCTGC CGβGTTCACA CGACβCCCTG CTGCCGCGAT 180
TAcccβeecG AGGAGTGCTβ TTCCGAGTGG GACTGCATGT GTGTCCAGCC TGAATTCCAC 240
TGCGGAGACC CTTGCTGCAC GACCTGCCGG CACCACCCTT GTCCCCCAGβ CCAGGGGGTA 300
CAGTCCCAGG GGAAATTCAG TTTTGGCTTC CAGTGTATCG ACTGTGCCTC GGGGACCTTC 360
TCCGGGGGCC ACGAAGGCCA CTGCAAACCT TGGACAGACT GCACCCAGTT CGGGTTTCTC 420
ACTGTGTTCC CTGGGAACAA GACCCACAAC GCTGTGTGCG TCCCAGGGTC CCCGCCGGCA 480
GAGC∞CTTG GGTGGCTGAC CGTCGTCCTC CTGGCCGTGG CCGCCTGCGT CCTCCTCCTG 540
ACCTCGGCCC AGCTTGGACT GCACATCTGG CAGCTGAGGA GTCAGTGCAT GTGGCCCCGA 600
GAGACCCAGC TGCTGCTGGA GGTGCCGCCG TCGACCGAAβ ACGCCAGAAβ CTGCCAGTTC 660
CCCGAGGAAG AGCGGGGCGA GCGATCCGCA GAGGAGAAGG GGCGGCTGGG AGACCTGTGG 720
GTGTGA 726
Seq ID NO : C122 DNA Sequence Nucleic Acid Accession ft : AK091896.1 Coding sequence : 28 . .1572
1 11 21 31 51
I I I
AGATCCGCGA GCCCGTCAGC CTGCGCCATG GGCTGCGACG GCCGCGTGTC GGGGCTGCTC 60 CGCCGCAACC TGCAGCCCAC GCTCACCTAC TGGAGCGTCT TCTTCAGCTT CGGCCTGTGC 120 ATCGCCTTCC TGGGGCCCAC GCTGCTGGAC CTGCGCTGTC AGACGCACAG CTCGCTGCCC 180 CAGATCTCCT GGGTCTTCTT CTCGCAβCAG CTCTGCCTCC TGCTGGGCAG CGCCCTCGGG 240 ββCCTCTTCA AAAGGACCCT GGCCCAGTCA CTATGGGCCC TGTTCACCTC CTCTCTGGCC 300 ATCTCCCTGG TGTTTGCCGT CATCCCCTTC TGCCGCGACG TGAAGGTGCT GGCCTCAGTC 360 ATGGCGCTGG CGGGCTTGGC CATGGGCTGC ATCGACACCG TGGCCAACAT GCAGCT6GTA 420 AGGATGTACC AGAAGGACTC GGCCGTCTTC CTCCAGGTGC TCCATTTCTT CGTGGGCTTT 480 GGTGCTCTGC TGAGCCCCCT TATTGCTGAC CCTTTCCTGT CTGAGGCCAA CTGCTTGCCT 540 GCCAATAGCA CGGCCAACAC CACCTCCCGA GGCCACCTGT TCCATGTCTC CAGGCTGCTG 600 GGCCACCACC ACGTAGATGC CAAGCCTTGG TCCAACCAGA CGTTCCCAGG GCTGACTCCA 660 AAGGACGGGG CAGGGACCCG AGTGTCCTAT GCCTTCTGGA TCATGGCCCT CATCGATCTT 720 CCAGTGCCCA TGGCTGTGCT GATGCTGCTG TCCAAGGAGC ββCTGCTGAC CTGCTGTCCC 780 CAGAGGAGGC CCCTGCTTCT GTCTGCTGAT GAGCTTGCCT TGβAGACACA GCCTCCTGAG 840 AAGGAAGATG CCTCCTCACT GCCCCCAAAG TTTCAGTCAC ACCTAGGGCA TGAGGACCTG 900 TTCAGCTGCT GCCAAAGGAA GAACCTCAGA GGAGCCCCTT ATTCCTTCTT TGCCATCCAC 960 ATCACGGGCG CCCTGGTACT GTTCATGACG GATGGGTTGA CGGGTGCCTA TTCCGGCTTC 1020 GTGTACAGCT ATGCTGTGGA GAAGCCCCTG TCTGTGGGAC ACAAGGTGGC TGGCTACCTC 1080 CCCAGCCTCT TCTGGGGCTT CATCACACTG GGCCGGCTCC TCTCCATTCC CATATCCTCA 1140 AGAATGAAGC CGGCCACCAT GGTTTTCATC AACGTGGTTG GCGT∞TGGT GACGTTCCTG 1200 GTGCTGCTTA TTTTCTCCTA GAACGTCGTC TTCCTGTTCG TGGGGACGGC AAGCCTGGGC 1260 CTGTTTCTCA GCAGCACCTT CCCCAGCATG CTGGCCTACA CGGAβGACTC GCTGCAGTAC 1320 AAAGGCTGTG CAACCACAGT GCTGGTGACA GGGGCAGGAG TTGGCβAGAT GGTGCTGCAG 1380 ATGCTGGTTG GTTCGATATT CCAGGCTCAG GGCAGCTATA GTTTCCTGβT CTGTGGCGTG 1440 ATCTTTGGTT GTCTGGCTTT TACCTTCTAT ATCTTGCTCC TGTTTTTCCA CAGGATGCAC 1500 CCTGGACTCC CATCAGTTCC TACCCAAGAC AGATCAATTG GAATGGAAAA CTCTGAGTGC 1560 TACCAGAGGT AAAACTβGGT GAAGAAββCA AGAGAAGACT TTCAGCCTCT TGATCACCAG 1620 CACGACCATA CTGTTTCAGA AAGCTGGGTG GTGGTGGAGG CGCTCTCTCA ATGGCTATTC 1680 AAGTCTTCTC CACTAAAACT TGGTTGGGTA GAGGAAATTA AATTGAGTCC TGGTACCTGG 1740 TCAAAATCAT TAGAAGTTTA CCTGGCTTCT CAAβTTATCT TCTTCCCTGG TTCACACTGT 1800 TGGTAAGAGC TGTCCAGATA CCCAGATGGG AAGGAAGGAG ACAGCCGCGC GCTTCACTCC 1860 ATTTGTCACC TCATGCATGG ACCATACTCT GGGTTTGAGA TCATTCTTCA TTGAAGTTTG 1920 TAAAAATAGG TTGAAATTGT AAAGCTCCAT GATCACTGCT ATATGTAGAT ATATTTCAAT 1980 TTAAGCAAAA CAAGCTGCAA GTTATTCCCT GGCATGCTCA AAGGATTTTC GTGCTTTTCA 2040 CTTAATAGTC CAAAGTCTCT TAAATTCCTG CTGCAGATAT CAATAGCTTA TCTATATTCT 2100 CAAACACCAA AAGGAAAAGT TGAATCTTGC TCTCTTTGβT ATACTAATGT AGTGGTATGC 2160 TAAGCTGGCT CATACCAACT TAGAAAAGCT GATTGTAAAA TTTTCATTTT GACAGCTGGT 2220 TATTAAATGC AGCCATTATT AAAAATCAAA TCATACAAAC TTATAATTAA ATCAATTACA 2280 TTTAAAACAA AGGTAATAAA . TATTCAAAGC ATATCACTTC CT 2322
Seq ID NO : C123 DNA Sequence Nucleic Acid Accession ft : NM_002203 .2
Coding sequence : 43 . .3588
11 21 31 CTGCAAACCC AGCGCAACTA CGGTCCCCCG GTCAGACCCA GGATGGGGCC AβAACGGACA 60
GGGGCCGCCC CGCTGCCGCT GCTGCTGGTG TTAGCGCTCA GTCAAGGCAT TTTAAATTGT 120
TGTTTGGCCT ACAATGTTGG TCTCCCAGAA GCAAAAATAT TTTCCGGTCC TTCAAGTGAA 180
CAGTTTGGGT ATGCAGTGCA GCAGTTTATA AATCCAAAAG βCAACTGGTT ACTGGTTGGT 240
TCACCCTGGA GTGGCTTTCC TGAGAACCGA ATGGGAGATG TGTATAAATG TCCTGTTGAC 300
CTATCCACTG CCACATGTGA AAAACTAAAT TTGCAAACTT CAACAAGCAT TCCAAATGTT 360
ACTGAGATGA AAACCAACAT GAGCCTCCGC TTGATCCTCA CCAGβAACAT GGGAACTGβA 420
GGTTTTCTCA CATGTGGTCC TCTGTGGGCA CAGCAATGTG GGAATCAGTA TTACACAACG 480
GGTGTGTGTT CTGACATCAG TCCTGATTTT CAGCTCTGAG CCAGCTTCTC ACCTGCAACT 540
CAGCCCTGCG CTTCCCTCAT AGATGTTGTG GTTGTGTGTβ ATGAATCAAA TAGTATTTAT 600
CCTTGGGATG CAGTAAAGAA TTTTTTGGAA AAATTTGTAC AAGGCCTTGA TATAGGCCCC 660
ACAAAGACAC AGGTGGGGTT AATTCAGTAT GCCAATAATC CAAGAGTTGT GTTTAACTTG 720
AACACATATA AAACCAAAGA AβAAATGATT GTAGCAACAT CCCAGACATC CCAATATGGT 780
GGGGACCTCA CAAACACATT CββAGCAATT CAATATGCAA GAAAATATGC CTATTCAGCA 840
GCTTCTGGTG GGCGACGAAG TGCTACGAAA GTAATGGTAG TTGTAACTGA CGGTGAATCA 900
CATGATGGTT CAAT6TTGAA AGCTβTGATT GATCAATGCA ACCATGACAA TATACTGAGG 960
TTTGGCATAG CAGTTCTTGG GTACTTAAAC AGAAACGCCC TTGATACTAA AAATTTAATA 1020
AAAGAAATAA AAGCGATCGC TAGTATTCCA ACAGAAAGAT ACTTTTTCAA TGTGTCTGAT 1080
GAAGCAGCTC TACTAGAAAA GGCTββGACA TTAGGA6AAC AAATTTTCAG CATTGAAGGT 1140
ACTGTTCAAG GAGβAGACAA CTTTCAGATG GAAATGTCAC AAGTGGGATT CAGTGCAGAT 1200
TACTCTTCTC AAAATGATAT TCTGATGCTG GGTβCAGTGG GAGCTTTTGG CTGGAGTGGG 1260
ACCATTGTCC AGAAGACATC TCATGGCCAT TTGATCTTTC CTAAACAAGC CTTTGACCAA 1320
ATTCTGCAGG ACAGAAATCA CAGTTCATAT TTAGβTTACT CTβTGGCTGC AATTTCTACT 1380
GGAGAAAGCA CTCACTTTGT TGGTGCTGCT CCTCGGβCAA ATTATACCGG CCAGATAGTβ 1440
CTATATAGTG TGAATGAGAA TGGCAATATC ACGGTTATTC AGGCTCACCG AGGTGACCAG 1500
ATTGGCTCCT ATTTTGGTAG TGTGCTGTGT TCAGTTGATG TGGATAAAGA CACCATTACA 1560
GACGTGCTCT TGGTAGGTGC ACCAATGTAC ATGAGTGACC TAAAGAAAGA GGAAGGAAGA 1620
GTCTACCTβT TTACTATCAA AAAGβGCATT TTGGGTCAGC ACCAATTTCT TGAAGGCCCC 1680
GAGGGCATTG AAAACACTCG ATTTGGTTCA GCAATTGCAG CTCTTTCAGA CATCAACATG 1740
GATGβCTTTA ATGATGTGAT TGTTGGTTCA CCACTAGAAA ATCAGAATTC TGGAGCTGTA 1800
TACATTTACA ATCGTCATCA GGGCACTATC CGCACAAAGT ATTCCCAGAA AATCTTGGGA 1860
TCCGATGGAG CCTTTAGGAG CCATCTCCAG TACTTTGGGA GGTCCTTGGA TGβCTATβGA 1920
GATTTAAATG GGGATTCCAT CACCGATGTβ TCTATTCGTG CCTTTGGACA AGTGGTTCAA 1980
CTCTGβTCAC AAAGTATTGC TGATGTAGCT ATAGAAGCTT CATTCACACC AβAAAAAATC 2040
ACTTTGGTCA ACAAGAATGC TCAGATAATT CTCAAACTCT GCTTCAGTGC AAAGTTCAGA 2100
CCTACTAAGC AAAACAATCA AGTGGCCATT GTATATAACA TCACACTTGA TGCAGATG6A 2160
TTTTCATCCA GAβTAACCTC CAGGGGGTTA TTTAAAGAAA ACAATGAAAG GTGCCTGCAG 2220
AAGAATATGG TAGTAAATCA AGCACAGAβT TβCCCCβAGC ACATCATTTA TATACAGGAG 2280
CCCTCTGATG TTGTCAACTC TTTGGATTTG CGTGTGGACA TCAGTCTGGA AAACCCTGGC 2340
ACTAβCCCTG CCCTTGAAGC CTATTCTβAG ACTGCCAAGG TCTTCAGTAT TCCTTTCCAC 2400
AAAGACTGTG GTGAGGATGG ACTTTGCATT TCTGATCTAG TCCTAGATGT CCGACAAATA 2460
CCAGCTGCTC AACAACAACC CTTTATTβTC AGCAACCAAA ACAAAAGGTT AACATTTTCA 2520
GTAACACTGA AAAATAAAAG GGAAAGTGCA TACAACACTG GAATTGTTGT TGATTTTTCA 2580
GAAAACTTGT TTTTTGCATC ATTCTCCCTA CCGGTTGATG GGACAGAAGT AACATGCCAG 2640
GTGGCTGCAT CTCAGAAGTC TGTTGCCTGC GATGTAGGCT ACCCTGCTTT AAAGAGAGAA 2700
CAACAGGTGA CTTTTACTAT TAACTTTGAC TTCAATCTTC AAAACCTTCA GAATCAGGCG 2760
TCTCTCAGTT TCCAAGCCTT AAGTGAAAGC CAAGAAGAAA ACAAGGCTGA TAATTTGGTC 2820
AACCTCAAAA TTCCTCTCCT GTATGATGCT GAAATTCACT TAACAAGATC TACCAACATA 2880
AATTTTTATG AAATCTCTTC GGATGGGAAT GTTCCTTCAA TCGTGCACAG TTTTGAAGAT 2940
GTTGGTCCAA AATTCATCTT CTCCCTGAAG GTAACAACAG GAAGTGTTCC AGTAAGCATG 3000
GCAACTGTAA TCATCCACAT CCCTCAGTAT ACCAAAGAAA AGAACCCACT GATGTACCTA 3060
ACTGGGGTGC AAACAGACAA GGCTGGTGAC ATCAGTTGTA ATGCAGATAT CAATCCACTG 3120
AAAATAGGAC AAACATCTTC TTCTGTATCT TTCAAAAGTG AAAATTTCAG GCACACCAAA 3180
GAATTGAACT GCAGAACTGC TTCCTGTAGT AATGTTACCT GCTGGTTGAA AGACGTTCAC 3240
ATGAAAGβAG AATACTTTGT TAATGTGACT ACCAGAATTT GGAACGGGAC TTTCGCATCA 3300
TCAACGTTCC AGACAGTACA GCTAACGGCA GCTGCAGAAA TCAACACCTA TAACCCTGAG 3360
ATATATGTGA TTGAAGATAA CACTGTTACG ATTCCCCTGA TGATAATGAA ACCTGATGAG 3420
AAAGCCGAAG TACCAACAGG AGTTATAATA GGAAGTATAA TTGCTGGAAT CCTTTTGCTG 3480
TTAGCTCTGG TTGCAATTTT ATGGAAGCTC GGCTTCTTCA AAAGAAAATA TGAAAAGATG 3540
ACCAAAAATC CAGATGAGAT TGATGAGACC ACAGAGCTCA GTAGCTGAAC CAGCAGACCT 3600 ACCTGCAGTG GGAACCGGCA GCATCCCAGC CAGGGTTTGC TGTTTGCGTβ CATGGATTTC 3660 TTTTTAAATC CCATATTTTT TTTATCATCT CGTAGβTAAA CTAACCTGGT ATTTTAAGAG 3720 AAAACTGCAG GTCAGTTTGG ATGAAGAAAT TGTGGGGGGT GGGGGAGGTG CGGGGGGCAG 3780 GTAGGGAAAT AATAGGGAAA ATACCTATTT TATATGATGG GGGAAAAAAA GTAATCTTTA 3840 AACTGGCTGG CCCAGAGTTT ACATTCTAAT TTGCATTGTG TCAGAAACAT GAAATGCTTC 3900 CAAGCATGAC AACTTTTAAA GAAAAATATG ATACTCTCAβ ATTTTAAβGG GGAAAACTGT 3960 TCTCTTTAAA ATATTTGTCT TTAAACAGCA ACTACAGAAG TGGAAGTGCT TGATATGTAA 4020 GTACTTCCAC TTGTGTATAT TTTAATGAAT ATTGATGTTA ACAAGAGGGG AAAACAAAAC 4080 ACAGGTTTTT TCAATTTATG CTGCTCATCC AAAβTTGCCA CAGATGATAC TTCCAAGTGA 4140 TAATTTTATT TATAAACTAG GTAAAATTTG TTGTTG6TTC CTTTTATACC ACGGCTGCCC 4200 CTTCCACACC CCATCTTGCT CTAATGATCA AAACATβCTT GAATAACTGA GCTTAGAGTA 4260 TACCTCCTAT ATGTCCATTT AAGTTAGGAG AGGGGGCβAT ATAGAGACTA AGGCACAAAA 4320 TTTTGTTTAA AACTCAGAAT ATAACATTTA TGTAAAATCC CATCTGCTAG AAGCCCATCC 4380 TGTβCCAGAG GAAGGAAAAG GAGGAAATTT CCTTTCTCTT TTAGGAGGCA CAACAGTTCT 4440 CTTCTAGGAT TTGTTTGGCT GACTGGCAGT AACCTAGTGA ATTTTTGAAA GATGAGTAAT 4500 TTCTTTGGCA ACCTTCCTCC TCCCTTACTG AACCACTCTC CCACCTCCTG GTGGTACCAT 4560 TATTATAGAA GCCCTCTACA GCCTGACTTT CTCTCCAGCG GTCCAAAGTT ATCCCCTCCT 4620 TTACCCCTCA TCCAAAGTTC CCACTCCTTC AGGACAGCTG CTGTGCATTA GATATTAGGG 4680 GGGAAAGTCA TCTGTTTAAT TTACACACTT GCATGAATTA CTGTATATAA ACTCCTTAAC 4740 TTCAGGGAGC TATTTTCATT TAGTGCTAAA CAAGTAAGAA AAATAAGCTA GAGTGAATTT 4800 CTAAATGTTG GAATGTTATG GGATGTAAAC AATGTAAAGT AAAACACTCT CAGGATTTCA 4860 CCAGAAGTTA CAGATGAGGC ACTGGAAACC ACCACCAAAT TAGCAGGTGC ACCTTCTGTG 4920 GCTGTCTTGT TTCTGAAGTA CTTTTTCTTC CACAAGAGTG AATTTGACCT AGGCAAGTTT 4980 GTTCAAAAGG TAGATCCTGA GATGATTTGG TCAGATTGGG ATAAGGCCCA GCAATCTβCA 5040 TTTTAACAAG CACCCCAGTC ACTAGGATGC AGATGGACCA CACTTTGAGA AACACCACCC 5100 ATTTCTACTT TTTGCACCTT ATTTTCTCTG TTCCTGAGCC CCCACATTCT CTAGGAGAAA 5160 CTTAGATTAA AATTCACAGA CACTACATAT CTAAAGCTTT GACAAGTCCT TGACCTCTAT 5220 AAACTTCAGA GTCCTCATTA TAAAATGGβA AGACTGAGCT GGAGTTCAGC AGTGATGCTT 5280 TTTAGTTTTA AAAGTCTATG ATCTGATCTG GACTTCCTAT AATACAAATA CACAATCCTC 5340 CAAGAATTTG ACTTGGAAAA G 5361
Seq ID NO: C124 DNA Sequence Nucleic Acid Accession #: NM_031460 Coding sequence: 103..1101
1 11 21 31 41 51
1 1 1 1 | 1 | 1 | 1 | 1 AGCAGGCGTT TGCGAGAGGA GATACGAGCT GGACGCCTGG CCCTTCCCTC CCACCGGGTC 60
CTAGTCCACC GCTCCCGGGG CCGGCTCCCC GCCTCTCCCG CTATGTACCG ACCGCGAGCC 120
CGGGCGGCTC CCGAGGGCAG GGTCCGGGGC TGCGCCβTβC CCAGCACCGT GCTCCTGCTG 180
CTCGGCTACC TGGCTTACCT GβCβCTGGGC ACCGGCGT6T TCTGβACGCT GGAGGGCCGC 240
GCGGCGCAGG ACTCCAGCCG CAGCTTCCAG CGCGACAAGT GGGAGCTGTT GCAGAACTTC 300
ACGTGTCTGG ACCGCCCGGC GCTGGACTCG CTGATCCGGG ATGTCGTCCA AGCATACAAA 360
AACGβAGCCA GCCTCCTCAG CAACACCACC AGCATGGGGC GCTGGGAGCT CGTGGβCTCC 420
TTCTTCTTTT CTGTGTCCAC CATCACCACC ATTGGCTATG GCAACCTGAG CCCCAACACG 480
ATGGCTGCCC GCCTCTTCTG CATCTTCTTT GCCCTTGTGG GGATCCCACT CAACCTCβTβ 540
GTGCTCAACC GACTGGGGCA TCTCATGCAG CAGGGAGTAA ACCACTGGGC CAGCAGGCTG 600
GGβGGCACCT GGCAGβATCC TGACAAGGCG CGGTGGCTGG CGGGCTCTGG CGCCCTCCTC 660
TCGGβCCTCC TGCTCTTCCT GCTGCTGCCA CCGCTGCTCT TCTCCCACAT GGAGβGCTGG 720
AGCTACACAG AGGGCTTCTA CTTCGCCTTC ATCACCCTCA GCACCGTGGG CTTCGGCGAC 780
TACGTGATTβ GAATGAACCC CTCCCAGAGG TACCCACTGT GGTACAAGAA CATGGTβTCC 840
CTGTGGATCC TCTTTGGGAT GGCATGGCTG GCCTTGATCA TCAAACTCAT CCTCTCCCAβ 900
CTGGAGACGC CAGGGAGGGT ATGTTCCTGC TGCCACCACA GCTCTAAGGA AGACTTCAAG 960
TCCCAAAGCT GGAGACAGGG ACCTGACCGG GAGCCAGAGT CCCACTCCCC ACAGCAAGGA 1020
TGCTATCCAG AGGβACCCAT GGGAATCATA CAGCATCTGG AACCTTCTGC TCACGCTGCA 1080
GβCTGTGGCA AGGACAGCTA GTTATACTCC ATTCTTTGGT CβTCβTCCTC GGTAGCAAGA 1140
CCCCTGATTT TAAβCTTTGC ACATGTCCAC CCAAACTAAA βACTACATTT TCCATCCACC 1200
CTAGAGGCTG GGTGCAGCTA TATGATTAAT TCTGCCCAAT AββGTATACA GAGACATGTC 1260
CTGGGTGACA TGGGATGTGA CTTTCGGGTG TCGGGGCAGC ATGCCCTTCT CCCCCACTTC 1320
CTTACTTTAG CGGβCTGCAA TGCCGCCGAT ATGATGGCTG GGAGCTCTGG CAGCCATACG 1380
GCACCATGAA GTAGCGGCAA TGTTTGAGCG GCACAATTAG ATAGGAAGAG TCTG6ATCTC 1440
TGATGATCAC AGAGCCATCC TAACAAACGG AATATCACCG ACCCTCCTTT ATGTβAβAGA 1500
GAAATAAACA TCTATGAAA 1519
Seq ID NO: C125 DNA Sequence Nucleic Acid Accession ff: NM_004154 Coding sequence: 309..1295
1 11 21 31 41 51
1 1 | 1 | 1 | 1 | 1 | 1 AAGGACAGAG GAGGβGCCCT TCCTCTCAGC TGGCTGGGAG CAGAGGTGGC TTTGTCTTTT 60
CGGAAβAACT GGTTCTGTGG AATTTGTGCT TATTTCCCAT CAAGGATCAA GGACCTGCTC 120
TGGGβCTACC TCAGGGCCCC ACAGGATGAG GGGCTGGTTT TCAGATGAGT TTTCTGCTTG 180
CCTGTCATCT GGATAβTβTC TAAAAATTTG CAAACTGCCT TCTTGTCAGT GTCTTGCTCA 240
TTCTTCATGA CACTCCTGAT ATGTCTCTCA GTTTCCTCAT CTGCTGCCTC TCCAGACTTC 300
TGCCAGAACA TTGCACGCGA CAGTTTCAGG CACAGAACTG ACTGGCAGCA GGGGCTGCTC 360
CACGAGTGGG AATTTGCTCC AGCACTTCAC GGACTGCAAG CGAGGCACTT GCTAACTCTT 420
GGATAACAAG ACCTCTGCCA GAAGAACCAT GGCTTTGβAA GGCGGAGTTC AGGCTGAGGA 480
GATGGGTGCG GTCCTCAGTG AGCCCCTGCC TCCCTGAACA TAGGAAACCC ACCTGGGCAG 540
CCATGGAATG GGACAATGGC ACAGGCCAGG CTCTGGGCTT GCCACCCACC ACCTGTGTCT 600
ACCGCGAGAA CTTCAAGCAA CTGCTGCTGC CACCTGTGTA TTCGGCGGTG CTGGCGGCTG 660
GCCTGCCGCT GAACATCTGT GTCATTACCC AGATCTGCAC GTCCCGCCGG GCCCTGACCC 720
GCACGGCCGT GTACACCCTA AACCTTGCTC TGGCTGACCT GCTATATGCC TGCTCCCTGC 780
CCCTGCTCAT CTACAACTAT GCCCAAGβTβ ATCACTG6CC CTTTGGCGAC TTCGCCTGCC 840
GCCTGGTCCG CTTCCTCTTC TATGCCAACC TGCACGGCAG CATCCTCTTC CTCACCTGCA 900
TCAGCTTCCA GCGCTACCTG GGCATCTGCC ACCCGCTGGC CCCCTGGCAC AAACGTGGGG 960
GCCGCCGGGC TGCCTGGCTA GTGTGTGTAG CCGTGTGGCT GGCCGTGACA ACCCAGTGCC 1020
TGCCCACAGC CATCTTCGCT GCCACAGGCA TCCAGCGTAA CCGCACTGTC TGCTATGACC 1080
TCAGCCCGCC TGCCCTGGCC ACCCACTATA TβCCCTATGG CATGGCTCTC ACTGTCATCG 1140
GCTTCCTGCT GCCCTTTGCT GCCCTGCTGG CCTGCTACTG TCTCCTGGCC TGCCGCCTβT 1200
GCCGCCAGGA TGGCCCGGCA GAGCCTGTGG CCCAGGAGCG GCGTGGCAAG GCGGCCCGCA 1260
TGβCCGTGGT GGTGGCTGCT GCCTTTGCCA TCAGCTTCCT GCCTTTTCAC ATCACCAAGA 1320
CAGCCTACCT GGCAGTGCGC TCGACGCCGG GCGTCCCCTG CACTGTATTG GAGGCCTTTG 1380
CAGCGGCCTA CAAAGGCACG CGGCCGTTTG CCAGTGCCAA CAGCGTGCTG GACCCCATCC 1440
TCTTCTACTT CACCCAGAAG AAGTTCCGCC GGCGACCACA TGAGCTCCTA CAβAAACTCA 1500
CAGCCAAATG GCAGAGGCAG GGTCGCTGAG TCCTCCAGGT CCTGGGCAGC CTTCATATTT 1560
GCCATTGTGT CCGGGGCACC AGGAGCCCCA CCAACCCCAA ACCATGCGGA GAATTAGAGT 1620
TCAGCTCAGC TGGGCATGGA GTTAAGATCC CTCACAGGAC CCAGAAGCTC ACCAAAAACT 1680
ATTTCTTCAG CCCCTTCTCT GGCCCAGACC CTGTGGβCAT GGAGATGGAC AGACCTGGGC 1740
CTGGCTCTTG AGAGGTCCCA GTCAGCCATG GAGAGCTGGG GAAACCACAT TAAGGTGCTC 1800
ACAAAAATAC AGTGTGACGT GTACTGTCAA AA 1832
Seq ID NO: C126 DNA Sequence Nucleic Acid Accession #: NM_007197 Coding sequence: 18..1763
11 21 31 ACACGTCCAA CGCCAGCATG CAGCGCCCGβ βCCCCCGCCT GTGGCTGGTC CTGCAGGTGA 60
TGGGCTCGTG CGCCGCCATC AGCTCCATGG ACATGGAGCG CCCGGGCGAC GGCAAATGCC 120
AGCCCATCGA GATCCCGATG TGCAAGGACA TCGGCTACAA CATGACTCGT ATGCCCAACC 180
TGATGββCCA CGAGAACCAG CGCGAGGCAβ CCATCCAGTT GCACGAGTTC GCGCCGCTGG 240
TGGAGTACGG CTGCCACGGC CACCTCCGCT TCTTCCTGTG CTCGCTGTAC GCGCCGATGT 300
GCACCGAGCA GGTCTCTACC CCCATCCCCG CCTGCCGGGT CATGTGCGAG CAGGCCCββC 360
TCAAGTGCTC CCCGATTATG GAGCAGTTCA ACTTCAAGTG GCCCGACTCC CTGβACTGCC 420
GGAAACTCCC CAACAAGAAC GACCCCAACT ACCTGTGCAT GGAGGCGCCC AACAACGGCT 480
CGGACGAGCC CACCCGGGGC TCGGGCCTGT TCCCGCCGCT βTTCCGGCCβ CAGCGGCCCC 540
ACAGCGCGCA GGAGCACCCG CTGAAGGACG GGGGCCCCGG ececeecGβc TGCGACAACC 600
CGGGCAAGTT CCACCACGTG GAGAAGAGCG CGTCGTGCGC GCCGCTCTCC ACGCCCGGCG 660
TGGACGTGTA CTGGAGCCGC GAGGACAAGC GCTTCGCAGT GGTCTGGCTG GCCATCTGββ 720
CGGTGCTGTG CTTCTTCTCC AGCGCCTTCA CCGTGCTCAC CTTCCTCATC GACCCGGCCC 780
GCTTCCGCTA CCCCGAGCGC CCCATCATCT TCCTCTCCAT GTGCTACTGC GTCTACTCCG 840
TGGGCTACCT CATCCGCCTC TTCGCCGGCG CCGAGAGCAT CGCCTGCGAC CGGGACAGCβ 900
GCCAGCTCTA TGTCATCCAG GAGGGACTGG AGAGCACCGG CTGCACGCTG GTCTTCCTGG 960
TCCTCTACTA CTTCGGCATG GCCAGCTCGC TGTGGTGGGT G6TCCTCACG CTCACCTGβT 1020
TCCTGGCCGC CGGCAAGAAβ TGGGGCCACG AGGCCATCGA AGCCAACAβC AGCTACTTCC 1080
ACCTGGCAGC CTGGGCCATC CCGGCββTβA AGACCATCCT GATCCTGGTC ATGCGCAGβG 1140
TGGCGGGβGA CGAGCTCACC GGGGTCTGCT ACGTGGGCAG CATGGACGTC AACGCGCTCA 1200
CCGGCTTCGT GCTCATTCCC CTGGCCTGCT ACCTGGTCAT CGGCACGTCC TTCATCCTCT 1260
CGGGCTTCGT GGCCCTβTTC CACATCCGGA GGGTGATGAA GACGββCGGC GAGAACACGG 1320
ACAAGCTGGA GAAGCTCATG GTGCGTATCG GGCTCTTCTC TGTGCTGTAC ACCGTGCCGG 1380
CCACCTGTGT GATCGCCTGC TACTTTTACG AACGCCTCAA CATGGATTAC TGβAAβATCC 1440
TGGCGβCGCA GCACAAGTGC AAAATGAACA ACCAGACTAA AACGCTGGAC TGCCTGATGG 1500
CCGCCTCCAT CCCCGCCGTG GAGATCTTCA TGGTGAAGAT CTTTATGCTG CTGGTGGTGG 1560
GGATCACCAG CGGGATGTGG ATTTGGACCT CCAAGACTCT GCAGTCCTGG CAGCAGGTGT 1620
GCAGCCGTAG GTTAAAGAAG AAGAGCCββA βAAAACCGGC CAGCGTGATC ACCAGCGGTG 1680
GGATTTACAA AAAAGCCCAG CATCCCCAGA AAACTCACCA CGGGAAATAT GA6ATCCCTG 1740
CCCAGTCGCC CACCTGCGTG TGAACAGGGC TGGAGββAAG GGCACAGGGG CGCCCGGAGC 1800
TAAGATGTGG TGCTTTTCTT GGTTGTGTTT TTCTTTCTTC TTCTTCTTTT TTTTTTTTTT 1860
ATAAAAGCAA AAGAGAAATA CATAAAAAAG TGTTTACCCT GAAATTCAGG ATGCTGTGAT 1920
ACACTGAAAG GAAAAATGTA CTTAAAGGGT TTTGTTTTGT TTTGGTTTTC CAGCGAAGGG 1980
AAGCTCCTCC AGTGAAGTAG CCTCTTGTGT AACTAATTTG TGGTAAAGTA GTTGATTCAG 2040
CCCTCAGAAG AAAACTTTTG TTTAGAGCCC TCCGTAAATA TACATCTGTG TATTTGAGTT 2100
GGCTTTGCTA CCCATTTACA AATAAGAGGA CAGATAACTG CTTTGCAAAT TCAAGAGCCT 2160
CCCCTGGGTT AACAAATGAG CCATCCCCAG GGCCCACCCC CAGGAAGGCC ACAGTGCT6G 2220
GceβCATCCc TGCAGAGGAA AGACAGGACC CGGGGCCCGC CTCACACCCC AGTGGATTTβ 2280
GAGTTGCTTA AAATAGACTC TGGCCTTCAC CAATAGTCTC TCTGCAAGAC AGAAACCTCC 2340
ATGAAACCTC ACATTTGTGA ACTCAAACGA TGTGCAATAC ATTTTTTTCT CTTTCCTTGA 2400
AAATAAAAAG AGAAACAAGT ATTTTGCTAT ATATAAAGAC AACAAAAGAA ATCTCCTAAC 2460
AAAAGAACTA AGAGGCCCAG CCCTCAGAAA CCCTTCAGTG CTACATTTTG TGGCTTTTTA 2520
ATGGAAACCA AGCCAATGTT ATAGACGTTT GGACTGATTT GTGGAAAGGA GGGGGGAAGA 2580
GGGAGAAG6A TCATTCAAAA GTTACCCAAA GGGCTTATTG ACTCTTTCTA TTGTTAAACA 2640
AATGATTTCC ACAAACAGAT CAGGAAGCAC TAGGTTGGCA GAGACACTTT GTCTAGTGTA 2700
TTCTCTTCAC AGTGCCAGGA AAGAGTGGTT TCTGCGTGTG TATATTTGTA ATATATGATA 2760
TTTTTCATGC TCCACTATTT TATTAAAAAT AAAATATGTT CTTTAAAAAA A 2811
Seq ID NO: C127 DNA Sequence Nucleic Acid Accession ft: NM_005761.1 Coding sequence: 250..4956
11 21 31
GCGAGGAGGA AACGGTGCCG GAGCGCGCAG GGCTTGCTGC CGCCACCGCC GCTGCACAGβ 60
CTGCCGGAGC GAGCCTGCCG CGCGCCGCCC TCCCCGCTCT CCTTCCTGGG CGAGCTGCGG 120
GGATGGββCβ GCCGCGGGAG CCCGAGCGCG CGCAGGAACC GCCGCCGCCG CCGCCCGCGT 180
CTCCGTTGCC GCGCGCCTGA GCCGCCGTCG CCGCCGCGCG CCCTGCCCGG GGGCGGCCCC 240
CCCAGCCCCA TGβAGGTCTC CCGGAGGAAG GCGCCGCCGC GCCCCCCGCG CCCCGCAGCG 300
CCACTGCCCC TGCTCGCCTA TCTGCTGGCA CTGGCGβCTC CCGGCCGGGG CeCGGACGAG 360
CCCGTGTGGC GGTCGGAGCA AGCCATCGGA GCCATCGCGG CGAGCCAGGA GGACGGCGTG 420
TTTGTGGCGA GCGGCAGCTG CCTGGACCAG CTGGACTACA GCCTGGAGCA CAGCCTCTCG 480
CGCCTGTACC GββACCAAGC GGGCAACTGC ACAGAGCCGG TCTCGCTGGC GCCCCCCGCG 540
CGGCCCCGGC CCβGGAGCAG CTTCAGCAAG CTGCTβCTGC CCTACCGCGA GGGGGCGGCC 600
GGCCTCGGGG GGCTGCTGCT CACCGGCTGG ACCTTCGACC GGGGCGCCTG CGAGGTGCGG 660
CCCCTGGGCA ACCTGAGCCG CAACTCCCTG CGCAACGGCA CCGAGGTGGT GTCGTGCCAC 720
CCGCAGGGCT CGACGGCCGG CGTGGTGTAC CGCGCGGGCC GGAACAACCG CTGGTACCTG 780
GCGGTGGCCG CCACCTACGT GCTGCCTGAG CCGGAGACGG CGAGCCGCTG CAACCCCGCG 840
GCATCCGACC ACGACACGGC CATCGCGCTC AAGGACACGG AGGGGCGCAG CCTGGCCACG 900
CAGGAGCTGG GGCGCCTCAA GCTGTGCGAG GGCGCGGGCA CCCTβCACTT CGTGGACGCC 960
TTTCTCTGGA ACGGCACCAT CTACTTCCCC TACTACCCCT ACAACTATAC GAGCGGCβCT 1020
GCCACCGGCT GGCCCAGCAT GGCGCGCATC GCGCAGAGCA CCGAGGTβCT GTTCCAGGβC 1080
CAGGCATCCC TCGACTGCGG CCACGβCCAC CCCGACGGCC GCCGCCTβCT CCTCTCCTCC 1140
AGCCTAGTGG AGGCCCTGGA CGTCTGβGCG GGAGTGTTCA GCGCGβCCGC TGGAGAGGGC 1200
CAGGAGCGGC GCTCCCCCAC CACCACGGCG CTCTGCCTCT TCAGAATGAG TCAGATCCAG 1260
GCGCGCβCCA AGAGGGTCAG CTGGGACTTC AAGACGGCCG AGAGCCACTG CAAAGAAGGG 1320
GATCAACCTG AAAGAGTCCA ACCAATCGCA TCATCTACCT TGATCCATTC CGACCTGACA 1380
TCCGTTTATG GCACCGTGGT AATGAACAGG ACTGTTTTAT TCTTGGGGAC TGGAGATGGC 1440
CAGTTACTTA AGGTTATTCT TGCTGAGAAT TTGACTTCAA ATTGTCCAGA GGTTATCTAT 1500
GAAATTAAAG AAGAGACACC TGTTTTCTAC AAACTCGTTC CTGATCCTGT GAAGAATATC 1560
TACATTTATC TAACAGCTGβ GAAAGAGGTG AGGAGAATTC GTGTTGCAAA CTGCAATAAA 1620
CATAAATCCT GTTCGGAGTG TTTAACAGCC ACAGACCCTC ACTGCGGTTG GTGCCATTCG 1680
CTACAAAGGT GCACTTTTCA AGGAGATTGT GTACATTCAG AGAACTTAGA AAACTGGCTG 1740
GATATTTCGT CTGGAGCAAA AAAGTGCCCT AAAATTCAGA TAATTCGAAG CACTAAAGAA 1800 AAGACTACAG TGACTATGβT βGGAAGCTTC TCTCCAAGAC ACTCAAAGTG CATGGTGAAG 1860
AATGTGGACT CTAGCAGGGA GCTCTGCCAG . AATAAAAGTC AGCCCAACCG GACCTGCACC 1920
TGTAGCATCC CAACCAGAGC AACCTACAAA GATGTTTCAG TTGTCAACGT GATGTTCTCC 1980 •
TTCGGTTCTT GGAATTTATC AGAGAGATTC . AACTTTACCA AGTGCTCATC ATTAAAAGAA 2040
TGCCCAGCAT GCGTA6AAAC TGGCTGCGCG TGGTGTAAAA GTGCAAGAAG GTGTATCCAC 2100
CCCTTCACAG CTTGCGACCC TTCTGATTAT GAGAGAAACC AGGAACAGTG TCCAGTGGCT 2160
GTCβAβAAGA CATCAGGAGG AGGAAGACCC AAGGAGAACA AGGGGAACAG AACCAACCAG 2220
GCTTTACAGG TCTTCTACAT TAAGTCCATT GAGCCACAGA AAGTATCGAC ATTAGββAAA 2280
AGCAACGTGA TAGTAACGGG AGCAAACTTT ACCCGGGCAT CβAACATCAC AATβATCCTG 2340
AAAGGAACCA GTACCTGTGA TAAGGATGTG ATACAGGTTA GCCATGTGCT AAATGACACC 2400
CACATGAAAT TCTCTCTTCC ATCAAGCCGG AAAGAAATGA AGGATGTGTG TATCCAGTTT 2460
GATGGTGGGA ACTGCTCTTC TGTGβGATCC TTATCCTACA TTGCTCTGCC ACATTGTTCC 2520
CTTATATTTC CTGCTACCAC CTGβATCAGT GGTGGTCAAA ATATAACCAT GATGG6CACA 2580
AATTTTGATG TAATTGACAA CTTAATCATT TCACATGAAT TAAAA6GAAA CATAAATGTC 2640
TCTGAATATT GTGTGGCGAC TTACTGCGGG TTTTTAGCCC CCAβTTTAAA βAβTTCAAAA 2700
GTGCGCACGA ATGTCACTGT GAAGCTGAGA GTACAAGACA CCTACTTGGA TTβTβGAACC 2760
CTGCAGTATC GGGAGGACCC CAGATTCACG GGGTATCGGG TGGAATCCGA G6TGGACACA 2820
GAACTGGAAG TGAAAATTCA AAAAGAAAAT GACAACTTCA ATATTTCCAA AAAAβACATT 2880
GAAATTACTC TCTTCCATGG GGAAAATGGG CAATTAAATT GCAGTTTTGA AAATATTACT 2940
AGAAATCAAG ATCTTACCAC CATCCTTTGC AAAATTAAAG GCATCAAGAC TGCAAGCACC 3000
ATTGCCAACT CTTCTAAGAA AGTTCGGGTC AAGCTGGGAA ACCTGGAGCT CTAC6TC6AG 3060
CAGGAGTCAG TTCCTTCCAC ATGGTATTTT CTGATTGTGC TCCCTGTCTT GCTAGTGATT 3120
GTCATTTTTG CGGCCGTGGG GGTGACCAGG CACAAATCGA AGGAGCTGAG TCGCAAACAG 3180
AGTCAACAAC TAGAATTGCT GGAAAGCβAG CTCCGGAAAG AGATACGTGA CGGCTTTGCT 3240
GAβCTCCAGA TGGATAAATT GGATGTGGTT GATAGTTTTG GAACTGTTCC CTTCCTTGAC 3300
TACAAACATT TTGCTCT6AG AACTTTCTTC CCTGAGTCAG GTGGCTTCAC CCACATCTTC 3360
ACTGAAGATA TGCATAACAG AGACGCCAAC GACAAGAATG AAAGTCTCAC AGCTTTGGAT 3420
GCCCTAATCT GTAATAAAAG CTTTCTTGTT ACTGTCATCC ACACCCTTGA AAAGCAGAAG 3480
AACTTTTCTG TGAAGGACAG GTGTCTGTTT GCCTCCTTCC TAACCATTGC ACTGCAAACC 3540
AAβCTCβTCT ACCTGACCAG CATCCTAGAG GTGCTGACCA GGGACTTGAT GGAACAGTGT 3600
AGTAACATGC AGCCGAAACT CAT6CTGAGA CGCACGβAβT CCGTCGTCGA AAAACTCCTC 3660
ACAAACTββA TGTCCGTCTG CCTTTCTGGA TTTCTCCGGG AGACTGTCGG AGAGCCCTTC 3720
TATTTGCTGG TGACGACTCT GAACCAGAAA ATTAACAAGG GTCCCGTGGA TGTAATCACT 3780
TGCAAAGCCC TGTACACACT TAATGAAβAC TGGCTGTTGT GGCAGGTTCC GGAATTCAGT 3840
ACTGTGGCAT TAAACGTCGT CTTTGAAAAA ATCCCGGAAA ACGAGAGTGC AGATGTCTGT 3900
CGGAATATTT CAGTCAATGT TCTCGACTGT GACACCATTG GCCAAGCCAA AGAAAAGATT 3960
TTCCAAGCAT TCTTAACCAA AAATβGCTCT CCTTATGGAC TTCAGCTTAA TGAAATTGGT 4020
CTTCA6CTTC AAATGGGCAC ACGACAGAAA βAACTTCTββ ACATCGACAG TTCCTCCGTG 4080
ATTCTTGAAβ ATGGAATCAC CAAGCTAAAC ACCATTβGCC ACTATGAGAT ATCAAATGGA 4140
TCCACTATAA AAGTCTTTAA GAAGATAGCA AATTTTACTT CAGATGTGGA GTACTCGGAT 4200
GACCACTGCC ATTTGATTTT ACCAGATTCG βAAβCATTCC AAGATGTGCA AGGAAAGAGA 4260
CATCGAGGGA AGCACAAGTT CAAAGTAAAA CAAATGTATC TGACAAAGCT GCTGTCGACC 4320
AAGGTGGCAA TTCATTCT6T GCTTGAAAAA CTTTTTAGAA GCATTTGGAG TTTACCCAAC 4380
AGCAβAβCTC CATTTCCTAT AAAATACTTT TTTGACTTTT TGGACGCCCA GGCTGAAAAC 4440
AAAAAAATCA CAGATCCTGA CGTCGTACAT ATTTGGAAAA CAAACAGCCT TCCTCTTCGC 4500
TTCTGGGTAA ACATCCTGAA GAACCCTCAG TTTGTCTTTG ACATTAAGAA GACACCACAT 4560
ATAGACGGCT GTTTGTCAGT GATTGCCCAG GCATTCATGG ATGCATTTTC TCTCACAGAβ 4620
CAGCAACTAG GGAAGGAAGC ACCAACTAAT AAGCTTCTCT ATGCCAAGGA TATCCCAACC 4680
TACAAAGAAβ AAβTAAAATC TTATTACAAA GCAATCAGGG ATTTGCCTCC ATTGTCATCC 4740
TCAGAAATGG AAGAATTTTT AACTCA6GAA . TCTAAGAAAC ATGAAAATGA ATTTAATGAA 4800
GAAGTGGCCT TGACAβAAAT TTACAAATAC ATCGTAAAAT ATTTTGATGA GATTCTAAAT 4860
AAACTAGAAA GAβAACβAGG GCTGGAAGAA . GCTCAGAAAC AACTCTTGCA TGTAAAAGTC 4920
TTATTTGATG AAAAGAAGAA ATGCAAGTGG ! ATGTAAGCAC TCTGGGGCCT GGCTTAATCT 4980
GGCAAAGTTC TTCAGACGAC TTGGGAGCAA . AATGGCTGCT TGAGCTACTC TGTGTCβTTA 5040
ATTTGTTGTT TGCACATAGG TTCCACTTTG ! GGCACTGTCT TTTTAAGAGA CCAAGGCACA 5100
TβCACAβCTT TTAGAAAGCA A 5121
Seq ID NO: C128 DNA Sequence Nucleic Acid Accession ft: NM_002185. Coding sequence: 23..1402
60
120
Figure imgf001283_0001
180
TTCACTGACC TGTGCTTTTG AGβACCCAβA TGTCAACACC ACCAATCTGG AATTTGAAAT 240
ATGTGGGGCC CTCGTGGAGG TAAAβTβCCT GAATTTCAGG AAACTACAAG AGATATATTT 300
CATCGAGACA AAGAAATTCT TACTGATTGG AAAGAGCAAT ATATGTGTGA AGGTTGGAGA 360
AAAGAGTCTA ACCTGCAAAA AAATAGACCT AACCACTATA GTTAAACCTG AGGCTCCTTT 420
TGACCTGAGT GTCATCTATC GGGAAGGAGC CAATGACTTT GTGGTGACAT TTAATACATC 480
ACACTTGCAA AAGAAGTATG TAAAAGTTTT AATGCATGAT GTAGCTTACC GCCAGGAAAA 540
GGATGAAAAC AAATGGACGC ATGTGAATTT ATCCAGCACA AAβCTCACAC TCCTGCAGAG 600
AAAGCTCCAA CCGGCAGCAA TGTATGAGAT TAAAGTTCGA TCCATCCCTβ ATCACTATTT 660
TAAAGβCTTC TGGAGTGAAT GGAGTCCAAG TTATTACTTC AGAACTCCAβ AGATCAATAA 720
TAGCTCAGGG GAGATGGATC CTATCTTACT AACCATCAGC ATTTTGAβTT TTTTCTCTGT 780
CGCTCTGTTG GTCATCTTGG CCTGTGTGTT ATGGAAAAAA AGGATTAAβC CTATCGTATG 840
GCCCAGTCTC CCCGATCATA AGAAGACTCT GGAACATCTT TGTAAGAAAC CAAGAAAAAA 900
TTTAAATGTG AGTTTCAATC CTGAAAGTTT CCTGGACTGC CAGATTCATA GGGTGGATGA 960
CATTCAAGCT AGAGATGAAG TGGAAGGTTT TCTGCAAGAT ACGTTTCCTC AGCAACTAGA 1020
AGAATCTGAG AAGCAGAGGC TTGGAGGGGA TGTGCAGAGC CCCAACTGCC CATCTGAGGA 1080
TGTAGTCGTC ACTCCAGAAA GCTTTGGAAG AGATTCATCC CTCACATGCC TGGCTGGGAA 1140
TGTCAGTGCA TGTGACGCCC CTATTCTCTC CTCTTCCAββ TCCCTAGACT GCAGGGAGAG 1200
TGGCAAGAAT GGGCCTCATG TGTACCAGGA CCTCCTGCTT AGCCTTGGGA CTACAAACAG 1260 CACGCTGCCC CCTCCATTTT CTCTCCAATC TGGAATCCTG ACATTGAACC CAGTTGCTCA 1320
GGGTCAGCCC ATTCTTACTT CCCTGGGATC AAATCAAGAA GAAGCATATG TCACCATGTC 1380
CAGCTTCTAC CAAAACCAGT GAAGTGTAAG AAACCCAGAC TGAACTTACC GTGAβCβACA 1440
AAβATGATTT AAAAGβGAAG TCTAGAGTTC CTAGTCTCCC TCACAGCACA GAGAAGACAA 1500
AATTAGCAAA ACCCCACTAC ACAGTCTGCA AGATTCTGAA ACATTGCTTT GACCACTCTT 1560
CCTGAGTTCA GTGGCACTCA ACATGAGTCA AGAGCATCCT GCTTCTACCA TGTGβATTTG 1620
GTCACAAGGT TTAAGGTGAC CCAATGATTC AGCTATTT 1658
Seq ID NO: C129 DNA Sequence
Nucleic Acid Accession #: NM_002722.1
Coding sequence: 15..302
1 11 21 31 41 51
I I I I I I
ACTCTGGACT CCGGATGGCT GCCGCACGCC TCTGCCTCTC CCTGCTGCTC CTGTCCACCT 60
GCGTGGCTCT GTTACTACAG CCACTGCTGG βTβCCCAβGG AGCCCCACTG GAGCCAGTGT 120
ACCCAGGGGA CAATGCCACA CCAGAGCAGA TGGCCCAGTA TGCAGCTGAT CTCCGTAGAT 180
ACATCAACAT GCTGACCAGG CCTAGGTATG GβAAAAβACA CAAAGAGGAC ACGCTGGCCT 240
TCTCGGAGTG GGGGTCCCCG CATGCTβCTG TCCCCAGGGA GCTCAGCCCG CTGGACTTAT 300
AATGCCACCT TCTβTCTCCT ACGACTCCAT GAGCAβCβCC AGCCCAGCTC TCCCCTCTGC 360
ACCCTTGGCT CTGGCCAAAG CTTGCTCCCT GCTCCCACAC AβGCTCAATA AAGCAAGTCA 420
AAGCC 425
Seq ID NO: C130 DNA Sequence
Nucleic Acid Accession ff: NM_032545.1
Coding sequence: 47..718
1 11 21 31 41 51
I I I I I I
AAACTGATCT TCAATGCACT AAβAGAAGGA GACTCTCAAA CCAAAAATGA CCTGGAGGCA 60
CCATGTCAGG CTTCTGTTTA CGGTCAGTTT GGCATTACAG ATCATCAATT TGGGAAACAG 120
CTATCAAAGA GAGAAACATA ACGGCGGTAG AGAGGAAGTC ACCAAGGTTG CCACTCAGAA 180
GCACCGACAG TCACCGCTCA ACTGGACCTC CAGTCATTTC GGAGAGGTGA CTGGGAGCGC 240
CGAGGGCTGG GGGCCGGAβG AGCCβCTCCC CTACTCCCGG GCTTTCGGAG AGGGTGCGTC 300
CGCGCGGCCG CGCTβCTGCA GGAACGGCGG TACCTGCGTG CTGGGCAGCT TCTGCGTGTG 360
CCCGGCCCAC TTCACCGGCC GCTACTGCGA GCATGACCAG AGGCGCAGTG AATGCGGCGC 420
CCTGGAGCAC GβAβCCTβGA CCCTCCGCGC CTGCCACCTC TGCAGCTGCA TCTTCGGGGC 480
CCTGCACTGC CTCCCCCTCC AGACGCCTGA CCGCTGTGAC CCGAAAGACT TCCTGGCCTC 540
CCACGCTCAC GGGCCGAGCG CCGGGGGCGC GCCCAGCCTG CTACTCTTGC TGCCCTGCGC 600
ACTGCTGCAC CGCCTCCTGC GCCCGGATGC GCCCGCGCAC CCTCGCTCCC TGGTCCCTTC 660
CGTCCTCCAG CCGβAβCGGC GCCCCTGCGG AAGGCCGGGA CTTGGGCATC GCCTTTAATT 720
TTCTATGTTG TAAATAATAG ATGTGTTTAG TTTACCGTAA GCTGAAGCAC TGGGTGAATA 780
TTTTTATTGG GTAATAAATA TTTTCATGAA AGCGCCAAAA AAAAAAAAAA AAAAAAAAAA 840
AAAAAA 846
Seq ID NO: C131 DNA Sequence
Nucleic Acid Accession ff: NM_006533.1
Coding sequence: 72..467
1 11 21 31 41 51
I I I I I I
AGGGAGAGAG GGAGGGGAGG AAATTGGAGA CCCCAGCACC CCCTTGCTCA CTCTCTTGCT 60
CACAGTCCAC GATGGCCCGG TCCCTGGTGT GCCTTGGTGT CATCATCTTG CTGTCTGCCT 120
TCTCCGGACC TGGTGTCAGG GGTGGTCCTA TGCCCAAβCT GGCTGACCGG AAβCTGTGTG 180
CGGACCAGGA GTGCAGCCAC CCTATCTCCA TGGCTGTGGC CCTTCAGGAC TACATGGCCC 240
CCGACTGCCG ATTCCTGACC ATTCACCGGG GCCAAGTGGT GTATGTCTTC TCCAAGCTGA 300
AGGGCCGTGG GCGGCTCTTC TG6GGAGGCA GCGTTCAββG AGATTACTAT GGAGATCTGG 360
CTGCTCGCCT GGGCTATTTC CCCAGTAGCA TTGTCCGAGA GGACCAGACC CTGAAACCTG 420
GCAAAGTCGA TGTGAAGACA GACAAATGGG ATTTCTACTG CCAGTGAGCT CAGCCTACCG 480
CTGGCCCTGC CGTTTCCCCT CCTTGGGTTT ATGCAAATAC AATCAGCCCA GTGCAAAC 538
Seq ID NO: C132 DNA Sequence Nucleic Acid Accession #: AB064272 Coding sequence: 1..708
1 11 21 31 41 51
I I I I I I
ATGACACAAG TCACAGAAAA GTCCACAGAA CACCCAGAAA AGACCACGTC AACCACAGAG 60
AAAACCACAA GAACCCCAGA AAAGCCTACG CTATACTCAG AGAAGACCAT ATGCACCAAA 120
GGGAAAAACA CACCAGTCCC AGAAAAGCCT ACAGAAAACC TGGGGAACAC CACACTGACC 180
ACTGAGACCA TAAAAGCCCC AGTAAAGTCC ACAGAAAACC CAGAAAAAAC AGCAGCAGTC 240
ACAAAGACTA TAAAACCTTC AGTCAAGGTC ACAββAGACA AATCTCTCAC TACTACCTCT 300
TCTCATCTAA ATAAAACTGA AGTTACTCAT CAβGTGCCCA CTGGTTCTTT CACCCTCATT 360
ACATCTAGAA CGAAGCTGAG TTCTATCACA TCAGAAβCCA CAG6AAACGA GAGCCATCCA 420
TACCTCAATA AAGATGGCTC ACAGAAAGGT ATCCACGCTG GACAGATGGG AGAGAATGAT 480
TCATTCCCTβ CATGGGCCAT AGTTATTGTG GTCCTGGTβG CTGTGATTCT CCTCCTGGTG 540
TTCCTTGGCC TGATCTTCTT GGTCTCCTAT ATGATGCGGA CACGCCGCAC ACTAACCCAG 600
AACACCCAGT ACAATGATGC AGAGGATGAG GGTGGCCCCA ATTCCTACCC GGTCTACCTG 660
ATGGAGCAGC AGAATCTTGG CATG6GCCAG ATCCCTTCCC CACGGTGA 708
Seq ID NO: C133 DNA Sequence
Nucleic Acid Accession #: NM_080870.1
Coding sequence : 3..710 AGATGACACA AGTCACAGAA AAGTCCACAG AACACCCAGA AAAGACCACG TCAACCACAG 60
AGAAAACCAC AAGAACCCCA GAAAAGCCTA CGCTATACTC AGAGAAGACC ATATGCACCA 120
AAGGβAAAAA CACACCAGTC CCAGAAAAGC CTACAGAAAA CCTGGGGAAC ACCACACTGA 180
CCACTGAGAC CATAAAAGCC CCAGTAAAGT CCACAGAAAA CCCAGAAAAA ACAGCAGCAG 240
TCACAAAGAC TATAAAACCT TCAGTCAAGβ TCACAGGAGA CAAATCTCTC ACTACTACCT 300
CTTCTCATCT AAATAAAACT GAAGTTACTC ATCAGGTGCC CACTGGTTCT TTCACCCTCA 360
TTACATCTAG AACGAAGCTG AGTTCTATCA CATCAGAAGC CACAGβAAAC GAGAGCCATC 420
CATACCTCAA TAAAGATGGC TCACAGAAAG GTATCCACGC TGGACAGATG GGAGAGAATG 480
ATTCATTCCC TGCATGGGCC ATAGTTATTG TGGTCCTGGT GGCTGTGATT CTCCTCCTGG 540
TGTTCCTTGG CCTGATCTTC TTGGTCTCCT ATATGATGCG GACACGCCGC ACACTAACCC 600
AGAACACCCA GTACAATGAT GCAGAGGATG AGGGTGGCCC CAATTCCTAC CCGGTCTACC 660
TGATGGAGCA GCAGAATCTT GGCATGGGCC AGATCCCTTC CCCACGGTGA TCTTGGAGTA 720
GGCGCCCAGC CCTββCTCTT CCATGCTCTG CCCCTTTCCT GGATGAGGAA CCGGACTCAC 780
AATTTCTATT TCCGGGACTA CAGGAAGGGC AGAGAATACT GACGGTTACC AGTATTAACC 840
CTTCATCTGT TCTTGAAACT GGTTGGβGAA TGAGGTGATA AGCAAGβAGG GTGTAAGTTT 900
AGGGGACAAA GAAGAAAGAA TGAATAATAC GAGCAGACAT TCTCTGTAGA AGGTAATGGT 960
CTGAGAATGA AAAGGTGTTT GATGGACATG TTGTGGGGGC ACCAATGCAG AACACTGCAC 1020
TGAGTCCTAA AGGAAGGACA GGAGCCTTAT AGGCAATGCC CCAβACTCAC TTGTGAGTGG 1080
GGTTTATGGG GAAAGGGAβG GACTGAβGGC AGAGTCTCTG GGTTTCAGGA CAGCATTATG 1140
TTATTTCCAT TCACTATTAC TTAAGAGTTT GTβTCTAAAC AGGCTCATCT CTGAGTTCTC 1200
AββACCCTTG CCCCCACCCC CATTTTTTTA ATGAAAAAAA AAAACAAAAA AAACGGATCC 1260
AAGAAGAAAA GAGAATTTAT TTCCTTCTCC ACTCTCTCCA TGCCCTGGAG AAAAAAAAGT 1320
CCAGAAβAAA TCATAAATAT CTCTCATCTA CATGGTTGCT TCCTCTTCCT CCCAAATCCC 1380
TTAGTTTTCC TAAATGTCTA CAGTGGACGC CCTGTTGGTT TGβCTTGCTG GGTTGTGGGT 1440
GGACACGCAA GGAGGGGATT TTTATTTGGC CAGCAGTCTC ACCCACTGAT CTCCACCCCA 1500
GACCTTCCCT GATTGGTGTC TCAGCATTTA TTTTCCTGTC TCTTCCACCA AAAGCCAβCT 1560
GTAGCTTTAT CTCGTAAAAG TTACCCATCT TCTCTACTGT CCCCATTCTC TCTCCTCCCA 1620
CCTTCACCCC AGATTCAAGT TTTCCTCCTT GTAGGCATTT CATCTGTGTG TGTTTTCTGG 1680
ATTTTCTCTC TCTCTTCTTA TGGCCATTTC ACCTTATTAC TGATTGGGTA GAGGGGGAAA 1740
AGGAGAATGA TGATGATAGT TTCCTTGTGT CTATTGACCT TTTTTATAAT AAAGTATAAC 1800
ATGTT 1805
Seq ID NO: C134 DNA Sequence
Nucleic Acid Accession ft : FGENESH predicted
Coding sequence : 1. .10674
11 21 31
ATGTββCCTC GCCTGGCCTT TTGTTGCTGG GβTCTGGCGC TCGTTTCGGG CTGββCGACC 60
TTTCAGCAGA TGTCCCCGTC GCGCAATTTC AGCTTCCGCC TCTTCCCCGA GACCβCGCCC 120
GGGGCCCCCG GGAGTATCCC CGcecceccc GCTCCTGGCG ACGAAGCGGC GGGGAGCAGA 180
GTGβAGCGGC TGGGCCAGGC GTTCceecGA CGCGTGCGGC TβCTGCGGGA GCTCAGCGAG 240
CGCCTGGAGC TTGTCTTCCT GGTGGATβAT TCGTCCAGCG TGββCGAAGT CAACTTCCGC 300
AGCGAGCTCA TGTTCGTCCG CAAGCTGCTG TCCGACTTCC CCGTGGTGCC CACGGCCACG 360
CGCGTGGCCA TCCTGACCTT CTCGTCCAAG AACTACCTGG TGCCGCGCβT CGATTACATC 420
TCCACCCGCC GCGCGCGCCA GCACAAGTGC GCGCTGCTCC TCCAAGAGAT CCCTGCCATC 480
TCCTACCGAG GTGGCGGCAC CTACACCAAG GGCGCCTTCC AGCAAGCCGC GCAAATTCTT 540
CTTCATGCTA GAGAAAACTC AACAAAAGTT GTATTTCTCA TCACTGATGG ATATTCCAAT 600
GGGGβAGACC CTAGACCAAT TGCAβCβTCA CTGCGAGATT CAG6AGTGGA GATCTTCACT 660
TTTGβCATAT GGCAAGGGAA CATTCGAGAG CTGAATGACA TGGCTTCCAC CCCAAAGGAG 720
GAGCACTGTT ACCTGCTACA CAGTTTTGAA GAATTTGAGG CTTTAGCTCβ CCGGGCATTG 780
CATGAAGATC TACCTTCTGG GAGTTTTATT CAAGATβATA TGGTCCACTG CTCATATCTT 840
TGTGATGAAG GCAAGGACTG CTGTβACCGA ATGGGAAGCT GCAAATGTGG GACACACACA 900
GGCCATTTTG AGTGCATCTG TGAAAAGGGG TATTACGGGA AAGGTCTGCA GTATGAATGC 960
ACAGCTTGCC CATCGGGGAC ATACAAACCT GAAGGCTCAC CAGGAGGAAT CAGCAGTTGC 1020
ATTCCATGTC CTGATβAAAA TCACACCTCT CCACCTGGAA GCACATCCCC TGAAGACTGT 1080
GTCTGCAGAG AGGGATACAG GGCATCTGGC CAGACCTGTG AACTTGTCCA CTGCCCTGCC 1140
CTGAA6CCTC CCGAAAATGG TTACTTTATC CAAAACACTT GCAACAACCA CTTCAATGCA 1200
GCCTGTββGG TCCGATGTCA CCCTGGATTT GATCTTGTGG GAAGCAβCAT CATCTTATGT 1260
CTACCCAATG GTTTGTGGTC CGGTTCAGAG AGCTACTGCA GAGTAAGAAC ATGTCCTCAT 1320
CTCCGCCAGC CGAAACATGG CCACATCAGC TGTTCTACAA GGGAAATGTT ATATAAGACA 1380
ACATGTTTGG TTGCCTGTGA TGAAGGGTAC AGACTAGAAG GCAGTGATAA GCTTACTTGT 1440
CAAGGAAACA GCCAGTGGGA TGGGCCAGAA CCCCGCTGTG TGGAGCGCCA CTGTTCCACC 1500
TTTCAGATGC CCAAAGATGT CATCATATCC CCCCACAACT GTGGCAAGCA GCCAGCCAAA 1560
TTTGGGAC6A TCTGCTATGT AAGTTGCCGC CAAGGGTTCA TTTTATCTGG AβTCAAAβAA 1620
ATGCTGAGAT GTACCACTTC TGβAAAATGG AATGTCGGAβ TTCAGGCAGC TGTGTGTAAA 1680
GACGTGGAGG CTCCTCAAAT CAACTGTCCT AAGGACATAG AGβCTAAGAC TCTGGAACAG 1740
CAAGATTCTβ CCAATGTTAC CTGGCAGATT CCAACAGCTA AAGACAACTC TGGTGAAAAG 1800
GTGTCAβTCC ACGTTCATCC AGCTTTCACC CCACCTTACC TTTTCCCAAT TGGAGATGTT 1860
GCTATCGTAT ACACGGCAAC TGACCTATCC GGCAACCAGβ CCAGCTGCAT TTTCCATATC 1920
AAGGTTATTG ATGCAGAACC ACCTGTCATA GACTGGTGCA GATCTCCACC TCCCGTCCAG 1980
GTCTCGGAGA AGGTACATGC CGCAAGCTGG GATGAGCCTC AGTTCTCAGA CAACTCAGGG 2040
GCTGAATTGG TCATTACCAG AAGTCATACA CAAGGAGACC TTTTCCCTCA AGGGGAGACT 2100
ATAGTACAGT ATACAGCCAC TGACCCCTCA GGCAATAACA G6ACATGTGA TATCCATATT 2160
GTCATAAAAG GTTCTCCCTG TGAAATTCCA TTCACACCTG TAAATGGGGA TTTTATATGC 2220
ACTGCAGATA ATACTGGAGT CAACTGTACA TTAACTTGCT TGGAGGGCTA TGATTTCACA 2280
GAAGGGTCTA CTGACAAβTA TTATTGTGCT TATGAAGATG GCGTCTGGAA ACCAACATAT 2340
ACCACTGAAT GGCCAGACTG TGCCAAAAAA CGTTTTGCAA ACCACGGGTT CAAGTCCTTT 2400
GAGATGTTCT ACAAAGCAGC TCGTTGTGAT GACACAGATC TGATGAAGAA GTTTTCTGAA 2460
GCATTTGAGA CGACCCTGGG AAAAATGGTC CCATCATTTT GTAGTGATGC AGAGGACATT 2520 GACTGCAGAC TGGAGGAGAA CCTGACCAAA AAATATTGCC TAGAATATAA TTATGACTAT 2580
GAAAATGGCT TTGCAATTGG ACCAGCTGGC TGGGGTGCAG CTAATAGGCT GGATTACTCT 2640
TACGATGACT TCCTGGACAC TGTGCAAGAA ACAGCCACAA GCATCGGCAA TGCCAAGTCC 2700
TCACGGATTA AAAGAAGTGC CCCATTATCT GACTATAAAA TTAAGTTAAT TTTTAACATC 2760
ACAGCTAGTG TGCCATTACC CGATGAAAGA AATGATACCC TTGAATGGGA AAATCAGCAA 2820
CGACTCCTTC AGACATTGGA AACTATCACA AATAAACTGA AAAGGACTCT CAACAAAGAC 2880
CCCATGTATT CCTTTCAGCT TGCATCAβAA ATACTTATAG CCGACAGCAA TTCATTAGAA 2940
ACAAAAAAGG CTTCCCCCTT CTGCAGACCA GGCTCAGTGC TGAGAGGGCG TATGTGTGTC 3000
AATTGCCCTT TGGGAACCTA TTATAATCTG GAACATTTCA CCTGTGAAAG CTGCCGGATC 3060
GGATCCTATC AAGATGAAGA AGGGCAACTT GAGTGCAAGC TTTGCCCCTC TGβGATGTAC 3120
ACGGAATATA TCCATTCAAG AAACATCTCT GATTGTAAAG CTCAGTGTAA ACAAGGCACC 3180
TACTCATACA GTGGACTTGA GACTTCTGAA TCGTGTCCAC TGGGCACTTA TCAGCCAAAA 3240
TTTGGTTCCC GGAGCTGCCT CTCGTGTCCA GAAAACACCT CAACTGTGAA AAGAGGAGCC 3300
GTGAACATTT CTGCATGTGG AGTTCCTTGT CCAGAAGGAA AATTCTCGCG TTCTGGGTTA 3360
ATGCCCTGTC ACCCATGTCC TCGTGACTAT TACCAACCTA ATGCAGGGAA GGCCTTCTGC 3420
CTGβCCTGTC CCTTTTATGG AACTACCCCA TTCGCTGGTT CCAGATCCAT CACAGAATGT 3480
TCAACTTCAG TTCTGAATAT TACTATTTTC GGTGGATTTG GGCATCTGGA βTTGTTAAAT 3540
TβTCCTTCTG AGGTTTTCCA TGAATGCTTC TTTAACCCTT GCCACAATAG TGβAACCTβC 3600
CAβCAACTTG GGCGTGGTTA TGTTTGTCTC TGTCCACTTG GATATACAββ CTTAAAβTβT 3660 βAAACAβACA TCβATGAGTG CAGCCCACTG CCTTGCCTCA ACAATGGAGT TTGTAAAGAC 3720
CTAGTTGGGG AATTCATTTG TGAGTGCCCA TCAGGTTACA CAGGTCAGCG GTGTGAAGAA 3780
AATATAAATG AGTGTAGCTC CAGTCCTTGT TTAAATAAAG GAATCTGTGT TGATGβTβTG 3840
GCTGGCTATC GTTGCACATβ TβTGAAAGGA TTTGTAGGCC TGCATTGTGA AACAGAAGTC 3900
AATGAATGCC AGTCAAACCC ATGCTTAAAT AATGCAβTCT GTGAAβACCA ββTTGGGGGA 3960
TTCTTGTGCA AATGCCCACC TGGATTTTTG GGTACCCGAT GTGGAAAGAA CGTCGATGAG 4020
TGTCTCAGTC AGCCATGCAA AAATGGAGCT ACCTGTAAAG ACGGTGCCAA TAGCTTCAGA 4080
TGCCTGTGTG CAGCTGGCTT CACAGβATCA CACTGTGAAT TGAACATCAA TGAATGTCAG 4140
TCTAATCCAT GTAGAAATCA GβCCACCTGT GTGGATGAAT TAAATTCATA CAGTTβTAAA 4200
TGTCAGCCAG GATTTTCAGG CAAAAGGTGT GAAACA6AAC A6TCTACAGG CTTTAACCTG 4260
GATTTTGAAG TTTCTGGCAT CTATGGATAT GTCATGCTAG ATββCATGCT CCCATCTCTC 4320
CATGCTCTAA CCTGTACCTT CTGGATGAAA TCCTCTGACG ACATGAACTA TGGAACACCA 4380
ATCTCCTATG CAGTTGATAA CGGCAGCGAC AATACCTTGC TCCTGACTGA TTATAACGGC 4440
TGGGTTCTTT ATGTGAATGG CAGGGAAAAG ATAACAAACT GTCCCTCGGT GAATGATGGC 4500
AGATGGCATC ATATTGCAAT CACTTGGACA AGTGCCAATG βCATCTGGAA AGTCTATATC 4560
GATGGGAAAT TATCTGACGG TGGTGCTGGC CTCTCTGTTG GTTTβCCCAT ACCTGGTGGT 4620
GGTGCGTTAG TTCTGGGGCA AGAGCAAGAC AAAAAAGβAβ AββGATTCAG CCCAGCTGAG 4680
TCTTTTGTGG GCTCCATAAG CCAGCTCAAC CTCTGβGACT ATGTCCTβTC TCCACAGCAG 4740
GTGAAGTCAC TGGCTACCTC CTGCCCAGAG GAACTCAβTA AAGGAAACGT GTTAGCATββ 4800
CCTGATTTCT TGTCAGGAAT TGTGGGGAAA GTGAAGATCG ATTCTAAGAG CATATTTTGT 4860
TCTGATTGCC CAC6CTTAGG AGGGTCAGTG CCTCATCTGA βAACTGCATC TGAAGATTTA 4920
AAGCCAGGTT CCAAAGTCAA TCTGTTCTGT GATCCAββCT TCCAβCTGGT CGGGAACCCT 4980
GTGCAGTACT GTCTGAATCA AGGACAGTββ ACACAACCAC TTCCTCACTG TGAACGCATT 5040
AGCTGTGGGG TβCCACCTCC TTTGGAGAAT GβCTTCCATT CAGCCGATGA CTTCTATGCT 5100
GβCAGCACAG TAACCTACCA GTGCAACAAT GβCTACTATC TATTGGGTGA CTCAAβGATG 5160
TTCTGTACAG ATAATGGGAG CTGGAACGGC GTTTCACCAT CCTGCCTTGA TGTCGATGAG 5220
TGTGCAGTTG GATCAGATTG TAβTβAGCAT GCTTCTTGCC TGAACGTAGA TGGATCCTAC 5280
ATATGTTCAT GTGTCCCACC βTACACAGGA GATGGGAAAA ACTGTβCAβA ACCTATAAAA 5340
TGTAAGGCTC CAGβAAATCC GGAAAATGGC CACTCCTCAG βTGAGATTTA TACAGTAGβT 5400 βCCGGAGTCA CATTTTCβTG TCAGGAAGGA TACCAGTTGA TββGAGTAAC CAAAATCACA 5460
TGTTTGGAGT CTGGAGAATG GAATCATCTA ATACCATATT GTAAAGCTGT TTCATGTGGT 5520
AAACCGGCTA TTCCAGAAAA TGGTTGCATT GAGGAGTTAG CATTTACTTT TGGCAGCAAA 5580
GTGACATATA GGTGTAATAA AGGATATACT CTGβCCGGTG ATAAAGAATC ATCCTGTCTT 5640
GCTAACAGTT CTTGGAGTCA TTCCCCTCCT GTGTGTGAAC CAGTGAAGTG TTCTAGTCCG 5700
GAAAATATAA ATAATGGAAA ATATATTTTG AGTGGGCTTA CCTACCTTTC TACTGCATCA 5760
TATTCATGCG ATACAGGATA CAGCTTACAG GGCCCTTCCA TTATTGAATG CACGCCTTCT 5820
GGCATCTGβG ACAGAGCGCC ACCTGCCTGT CACCTCGTCT TCTGTGGAGA ACCACCTGCC 5880
ATCAAAGATG CTGTCATTAC GGGGAATAAC TTCACTTTCA GGAACACCGT CACTTACACT 5940
TGCAAAGAAG GCTATACTCT TGCTGGTCTT GACACCATTG AATGCCTGGC CGACGGCAAG 6000
TCGAβTAGAA GTGACCAGCA GTGCCTGGCT GTCTCCTGTβ ATGAGCCACC CATTGTGGAC 6060
CACGCCTCTC CAGAGACTGC CCATCGGCTC TTTβGAGACA TTGCATTCTA CTACTGCTCT 6120
GATGGTTACA GCCTAGCAGA CAATTCCCAG CTTCTCTGCA ATGCCCAGGG CAAGTGGGTA 6180
CCCCCAGAAG GTCAAGACAT GCCCCGTTGT ATAGCTCATT TCTGTGAAAA ACCTCCATCG 6240
GTTTCCTATA GCATCTTGGA ATCTGTGAGC AAAGCAAAAT TTGCAβCTβG CTCAGTTGTG 6300
A6CTTTAAAT GCATGGAAGG CTTTGTACTG AACACCTCAG CAAAGATTGA ATGTATGAGA 6360
GGTGGβCAGT GGAACCCTTC CCCCATGTCC ATCCAGTGCA TCCCTGTGCG GTGTGGAGAG 6420
CCACCAAGCA TCATGAATGG CTATGCAAGT GβATCAAACT ACAGTTTTGG AGCCATGGTG 6480
GCTTACAGCT GCAACAAGGG GTTCTACATC AAAGG6GAAA AGAAGAGCAC CTGCGAAGCC 6540
ACAGββCAGT βGAGTAGTCC TATACCGACG TGCCACCCGG TATCTTGTGG TGAACCACCT 6600
AAGGTTGAGA ATGGCTTTCT GGAGCATACA ACTGGCA∞A TCTTTGAGAG TGAAGTGAGG 6660
TATCAGTGTA ACCCGGGCTA TAAGTCAGTC GGAAGTCCTG TATTTGTCTG CCAAGCCAAT 6720
CGCCACTGGC ACAGTGAATC CCCTCTGATG TGTGTTCCTC TCGACTGTGG AAAACCTCCC 6780
CCGATCCAGA ATGGCTTCAT GAAAGGAGAA AACTTTGAAG TAGGGTCCAA GGTTCAGTTT 6840
TTCTGTAATG AGGGTTATGA GCTTGTTGβT GACAGTTCTT GGACATGTCA GAAATCTGGC 6900
AAATGGAATA AGAAGTCAAA TCCAAAGTGC ATGCCTGCCA AGTGCCCAGA βCCGCCCCTC 6960
TTGGAAAACC AGCTAGTATT AAAGGAGTTG ACCACCGAGG TAGGAGTTGT GACATTTTCC 7020
TGTAAAβAAβ GGCATGTCCT GCAAGGCCCC TCTGTCCTGA AATGCTTGCC ATCCCAGCAA 7080
TGGAATGACT CTTTCCCTGT TTGTAAβATT GTTCTTTGTA CCCCACCTCC CCTAATTTCC 7140
TTTGGTGTCC CCATTCCTTC TTCTGCTCTT CATTTTGGAA GTACTβTCAA GTATTCTTGT 7200
GTAGGTGGGT TTTTCCTAAG AGGAAATTCT ACCACCCTCT GCCAACCTGA TGGCACCTGG 7260
AGCTCTCCAC TGCCAGAATG TGTTCCAGTA GAATGTCCCC AACCTGAGβA AATCCCCAAT 7320
GGAATCATTG ATGTGCAAGG CCTTGCCTAT CTCAGCACAG CTCTCTATAC CTGCAAGCCA 7380
GGCTTTGAAT TGGTGGGAAA TACTACCACC CTTTGTGβAG AAAATGGTCA CTGGCTTGGA 7440
GGAAAACCAA CATGTAAAGC CATTGAGTGC CTGAAACCCA A6GAGATTTT GAATGGCAAA 7500
TTCTCTTACA CGGACCTACA CTATGGACAG ACCGTTACCT ACTCTTGCAA CCGAGGCTTT 7560 CGGCTCGAAG GTCCCA6TGC CTTGACCTGT TTAGAGACAG GTGATTGGGA TGTAGATGCC 7620 CCATCTTGCA ATGCCATCCA CTGTGATTCC CCACAACCCA TTGAAAATGG TTTTGTAGAA 7680 GGTGCAGATT ACAGCTATGG TGCCATAATC ATCTACAGTT GCTTCCCTGG GTTTCAGGTβ 7740 GCTGGTCATG CCATGCAGAC CTGTGAAGAG TCAβGATβGT CAAβTTCCAT CCCAACATGT 7800 ATGCCAATAG ACTGTGGCCT CCCTCCTCAT ATACATTTTβ GAGACTGTAC TAAACTCAAA 7860 GATGACCAGG GATATTTTGA GCAAGAAGAC GACATGATGG AAGTTCCATA TGTGACTCCT 7920 CACCCTCCTT ATCATTTGGG AGCAGTGGCT AAAACCTGββ AAAATACAAA GGAGTCTCCT 7980 GCTACACATT CATCAAACTT TCTGTATβGT ACCATGGTTT CATACACCTG TAATCCAGGA 8040 TATGAACTTC TGGGGAACCC TGTGCTGATC TGCCAGGAAG ATGGAACTTG GAATβGCAGT 8100 GCACCATCCT GCATTTCAAT TGAATGTGAC TTβCCTACTG CTCCTGAAAA TβGCTTTTTG 8160 CGTTTTACAG AGACTAGCAT GGGAAGTGCT GTGCAGTATA GCTβTAAACC TGGACACATT 8220 CTAGCAGβCT CTGACTTAAG GCTTTGTCTA GAGAATAGAA AGTGβAGTGG TGCCTCCCCA 8280 CGCTGTGAAG CCATTTCATG CAAAAAGCCA AATCCAGTCA TβAATββATC CATCAAAGβA 8340 AGCAACTACA CATACCTGAG CACGTTGTAC TATGAGTβTG ACCCCGGATA TGTGCTβAAT 8400 GGCACTβAGA GGAGAACATG CCAGGATGAC AAAAACTGβG ATGAGGATGA GCCCATTTGC 8460 ATTCCTGTGG ACTGCAGTTC ACCCCCAGTC TCAGCCAATβ GCCAGβTGAG AββAGACGAβ 8520 TACACATTCC AAAAAGAGAT TGAATACACT TGCAATGAAG GGTTCTTGCT TβAββGAGCC 8580 AGGAGTCGGG TTTGTCTTGC CAATGGAAGT TGGAGTGGAG CCACTCCCGA CTβTβTβCCT 8640 GTCAGATGTG CCACCCCGCC ACAACTGGCC AATGGGGTGA CGGAAGGCCT GGACTATGGC 8700 TTCATGAAGG AAGTAACATT CCACTGTCAC GAGGGCTACA TCTTGCACGG TGCTCCAAAA 8760 CTCACCTGTC AGTCAGATGG CAACTGGGAT GCAGAGATTC CTCTCTGTAA ACCAGTCAAC 8820 TGTGGACCTC CTGAAGATCT TGCCCATGGT TTCCCTAATG GTTTTTCCTT TATTCATGGβ 8880 GGCCATATAC AGTATCAGTG CTTTCCTGGT TATAAGCTCC ATGGAAATTC ATCAAGAAGG 8940 TGCCTCTCCA ATGGCTCCTβ GAβTββCAGC TCACCTTCCT GCCTGCCTTG CAGATGTTCC 9000 ACACCAGTAA TTGAATATββ AACTGTCAAT GGGACAGATT TTGACTGTGG AAAGGCAGCC 9060 CGGATTCAGT GCTTCAAAGG CTTCAAGCTC CTAGGACTTT CTGAAATCAC CTGTGAAGGC 9120 GATG6CCAGT GGAGCTCTGG GTTCCCCCAC TGTGAACACA CTTCTTGTGG TTCTCTTCCA 9180 ATβATACCAA ATGCGTTCAT CAGTGAGACC AGCTCTTGβA AGGAAAATGT GATAACTTAC 9240 AGCTGCAGGT CTGGATATGT CATACAAGGC AβTTCAGATC TGATTTGTAC AGAGAAAGGG 9300 GTATGGAGCC AGCCTTATCC AGTCTGTGAG CCCTTGTCCT GTGGGTCCCC ACCGTCTGTC 9360 GCCAATGCAG TGβCAACTββ AGAGGCACAC ACCTATGAAA GTGAAGTGAA ACTCAGATGT 9420 CTGGAAGGTT ATACGATGGA TACAGATACA GATACATTCA CCTGTCAGAA AGATGGTCGC 9480 TGGTTCCCTG AGAGAATCTC CTGCAGTCCT AAAAAATGTC CTCTCCCGGA AAACATAACA 9540 CATATACTTG TACATGGGGA CGATTTCAGT GTGAATAGGC AAGTTTCTGT GTCATGTGCA 9600 GAAGGGTATA CCTTTGAGGG AGTTAACATA TCAGTATGTC AGCTTGATGG AACCTGGGAG 9660 CCACCATTCT CCGATGAATC TTβCAGTCCA GTTTCTTGTG GGAAACCTGA AAGTCCAGAA 9720 CATGGATTTG TGGTTGGCAG TAAATACACC TTTGAAAGCA CAATTATTTA TCAGTGTGAG 9780 CCTGGCTATG AACTAGAGGG GAACAGGGAA CGTGTCTGCC AGGAGAACAG ACAGTGGAGT 9840 GGAGGGGTGG CAATATGCAA AGAGACCAGG TGTGAAACTC CACTTGAATT TCTCAATGGG 9900 AAACCTGACA TTGAAAACAβ GACGACTGGA CCCAACGTGG TATATTCCTG CAACAGAGGC 9960 TACAGTCTTG AAGGGCCATC TGAGβCACAC TGCACAGAAA ATGGAACCTG GAGCCACCCA 10020 GTCCCTCTCT eCAAACCAAA TCCATβCCCT GTTCCTTTTG TGATTCCCGA GAATGCTCTG 10080 CTGTCTGAAA AβGAGTTTTA TGTTGATCAG AATGTGTCCA TCAAATGTAG GGAAGGTTTT 10140 CTGCTGCAGG GCCACGβCAT CATTACCTGC AACCCCGACG AGACGTGGAC ACAGACAAGC 10200 GCCAAATGTG AAAAAATCTC ATGTGGTCCA CCAGCTCACG TAGAAAATGC AATTGCTCGA 10260 GGCGTACATT ATCAATATGG AGACATGATC ACCTACTCAT CTTACAGTββ ATACATGTTG 10320 GAGGGTTTCC TGAGGAGTGT TTGTTTAGAA AATGGAACAT βGACATCACC TCCTATTTβC 10380 AGAGCTGTCT GTCGATTTCC : ATGTCAGAAT GGGGGCATCT GCCAACGCCC AAATGCTTGT 10440 TCCTGTCCAβ ACGGCTGGAT GGGβCβCCTC TGTGAAGAAC CAATCTGCAT TCTTCCCTGT 10500 CTGAACβGAG GTCGCTCTβT eeccccTTAc CAGTGTGACT GCCCGCCTGG CTGGACGGGG 10560 TCTCGCTGTC ATACAGCTGT ' TTβCCAβTCT CCCTGCTTAA ATGGTGGAAA ATGTGTAAGA 10620 CCAAACCGAT GTCACTGTCT ' TTCTTCTTGG ACGGGACATA ACTGTTCCAG GTAA 10674
Seq ID NO: C135 DNA Sequence Nucleic Acid Accession ft: FGENESH predicted Coding sequence: 1..390
60
120
180
Figure imgf001287_0001
240
TGCACCTTCT GGCCCTGCTT TGAGCTCTβC TGTCTTGATT CCTTTGGCCT CACAAACGAT 300
TTTGTTGTGA AGCTGAAGGT TCAGGGTGTG AATTCCCAGT GCCACTCATC TCCCATCTCC 360
AGTAAATGTG AAAGAGGCCG GATATGTTAG 390
Seq ID NO: C136 DNA Sequence Nucleic Acid Accession ft: BC035671.1
Coding sequence : 126. .1745
1 11 21 31 41 51
1 1 | 1 | 1 | 1 I
1 | 1 GGCAGCGACT GCβCCCCGTC CCGGCGCCGC GCTCGTCCGC AGAGGAGGCG GCCCGGCCCG 60
GGCAGCTGCG GCTCGGGATC CGTCGAGGGG AGGCCGAGCT TGCCAAGCTG GCβCCCAGCG 120
GGGTCATGGT GCCCGGCGCC CGCGGCGGCG GCGCACTGGC GCGGGCTGCC GGGCGGGGCC 180
TCCTGGCTTT GCTGCTCGCG GTCTCCGCCC CGCTCCGGCT GCAGGCGGAG βAβCTGGGTG 240
ATGGCTGTGG ACACCTAGTG ACTTATCAGβ ATAGTGβCAC AATGACATCT AAGAATTATC 300
CCGGGACCTA CCCCAATCAC ACTGTTTGCβ AAAAGACAAT TACAGTACCA AAGGGGAAAA 360
GACTGATTCT GAGGTTGGGA GATTTGGATA TCGAATCCCA GACCTGTGCT TCTGACTATC 420
TTCTCTTCAC CAGCTCTTCA GATCAATATG GTCCATACTG TGGAAGTATG ACTGTTCCCA 480
AAGAACTCTT- GTTGAACACA AGTGAAGTAA CCCTCCGCTT TGAGAGTGGA TCCCACATTT 540
CTGβCCGGGG TTTTTTGCTG ACCTATGCGA GCAGCGACCA TCCAGATTTA ATAACATGTT 600 TGGAACGAGC TAβCCATTAT TTGAAGACAG AATACAGCAA ATTCTGCCCA GCTGGTTGTA 660
GAGACGTAGC AGGAGACATT TCTGGGAATA TGGTAGATGG ATATAGAGAT ACCTCTTTAT 720
TGTGCAAAGC TGCCATCCAT GCAGGAATAA TTGCTGATGA ACTAGGTGGC CAGATCAGTG 780
TGCTTCAGCG CAAAGβGATC AGTCβATATG AAGGGATTCT GGCCAATGGT GTTCTTTCGA 840
GGGATGGTTC CCTGTCAGAC AAGCGATTTC TGTTTACCTC CAATGGTTGC AGCAGATCCT 900
TGAGTTTTGA ACCTβACGGG CAAATCAGAβ CTTCTTCCTC ATGGCAGTCG GTCAATGAGA 960
GTGGAGACCA AGTTCACTGG TCTCCTGGCC AAGCCCGACT TCAGGACCAA GGCCCATCAT 1020
GGGCTTCGGG CGACAGTAGC AACAACCACA AACCACGAGA GTGGCTGGAG ATCGATTTGG 1080
GGGAGAAAAA GAAAATAACA G6AATTAGGA CCACAGGATC TACACAβTCG AACTTCAACT 1140
TTTATGTTAA GAGTTTTGTG ATβAACTTCA AAAACAATAA TTCTAA6TGG AAGACCTATA 1200
AAGGAATTGT GAATAATGAA GAAAAGGTGT TTCAGGGTAA CTCTAACTTT CGGGACCCAG 1260
TGCAAAACAA TTTCATCCCT CCCATCGTGG CCAGATATGT GCGGGTTGTC CCCCAGACAT 1320
GGCACCAGAG GATAGCCTTG AAGGTGβAGC TCATTGGTTG CCAGATTACA CAAGGTAATG 1380
ATTCATTGGT GTGGCGCAAG ACAAGTCAAA GCACCAGTGT TTCAACTAAG AAAGAAGATG 1440
AGACAATCAC AAGGCCCATC CCCTCGβAAG AAACATCCAC AGGAATAAAC ATTACAACGG 1500
TGGCTATTCC ATTGGTGCTC CTTGTTGTCC TGGTGTTTGC TGGAATGGGG ATCTTTGCAG 1560
CCTTTAGAAA GAAGAAGAAG AAAGGAAGTC CGTATGGATC AGCAGAGGCT CAGAAAACAG 1620
ACTβTTGGAA GCAGATTAAA TATCCCTTTG CCAGACATCA GTCAGCTGAG TTTACCATCA 1680
GCTATGATAA TGAGAAGGAG ATGACACAAA AGTTAGATCT CATCACAAGT GATATGGCAG 1740
GTTAACTCCG TTGACTGCCA AAATAGCATC CCCAACGTGC AGCCCTCCGC ATCTATCAGC 1800
AGGTTβCCCC GGATGGATCT CAGAGATGAG GATCGGAACA CCATGTTCTT TCCCACCCTA 1860
ACAACAACAA AGGGCAGTAA ATTAAAGTAC TCTTTGTAAG GTACAGTTAC CGATTAATCT 1920
AGAGATAAAA TATTTTCTTA AAAATATATT TCATTAAACA CCTATGCTGT CTCTATAAAA 1980
AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 2010
Seq ID NO: C137 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 1..1761
1 11 21 31 41 51
I 1 I. I I I
ATGGGATTCG GTGCGGGGCA GCGACTGCGC CCCGTCCCββ CGCCβCGCTC GTCCGCAGAG 60
GAGGCGGCCC GGCCCGGGCA GCTGCGGCTC GGβATCCGTC GAGGGGAGGC CGAGCTTGCC 120
AAGCTGGCβC CCAGCGGGGT CATGGTGCCC GGCGCCCGCG GCGGCGGCGC ACTGGC6CGG 180
GCTGCCeeβC GGGGCCTCCT GGCTTTGCTG CTCGCGGTCT CCGCCCCβCT CCGGCTGCAG 240
GCGGAGGAGC TGGGTGATGG CTCTGGACAC CTAGTGACTT ATCAGGATAG TGGCACAATG 300
ACATCTAAβA ATTATCCCGG GACCTACCCC AATCACACTG TTTGCGAAAA GACAATTACA 360
GTACCAAAGG GGAAAA6ACT CATTCTGAGG TTGGGAGATT TGGATATCGA ATCCCAGACC 420
TGTGCTTCTG ACTATCTTCT CTTCACCAGC TCTTCAGATC AATATGGTCC ATACTGTGGA 480
AGTATGACTG TTCCCAAAGA ACTCTTGTTG AACACAAGTG AAβTAACCGT CCGCTTTGAG 540
AGTGGATCCC ACATTTCTGG CCGGGGTTTT TTGCTGACCT ATGCGAGCAG CGACCATCCA 600
GATTTAATAA CATGTTTGβA ACGAGCTAGC CATTATTTGA AGACAGAATA CAGCAAATTC 660
TGCCCAGCTG GTTGTAGAβA CβTAGCAGGA GACATTTCTG GGAATATGGT AGATGGATAT 720
AGAGATACCT CTTTATTGTG CAAAβCTGCC ATCCATGCAG GAATAATTGC TGATGAACTA 780
GGTGGCCAGA TCAGTGTGCT TCAGCGCAAA GGGATCAGTC GATATGAAGG GATTCTGGCC 840
AATGGTGTTC TTTCGAGGGA TGGTTCCCTG TCAGACAAGC GATTTCTGTT TACCTCCAAT 900
GGTTGCAGCA GATCCTTGAG TTTTGAACCT GACGGGCAAA TCAGAGCTTC TTCCTCATGG 960
CAGTCGGTCA ATGAGAGTGG AGACCAAGTT CACTGGTCTC CTGGCCAAGC CCGACTTCAG 1020
GACCAAGGCC CATCATGGGC TTCGGGCGAC AGTAGCAACA ACCACAAACC ACGAGAGTGG 1080
CTGGAGATCG ATTTGβGGβA GAAAAAGAAA ATAACAGGAA TTAGGACCAC AGGATCTACA 1140
CAGTCGAACT TCAACTTTTA TGTTAAGAGT TTTGTGATGA ACTTCAAAAA CAATAATTCT 1200
AAGTGGAAGA CCTATAAAGβ AATTβTβAAT AATGAAGAAA AGGTGTTTCA GGGTAACTCT 1260
AACTTTCGGG ACCCAGTGCA AAACAATTTC ATCCCTCCCA TCGTGGCCAβ ATATGTGCGG 1320
GTTGTCCCCC AGACATGGCA CCAGAGGATA GCCTTGAAGG TGGAGCTCAT TGβTTβCCAG 1380
ATTACACAAG GTAATGATTC ATTGGTGTGG CGCAAGACAA GTCAAAGCAC CAβTβTTTCA 1440
ACTAAGAAAG AAGATβAGAC AATCACAAGG CCCATCCCCT CGGAAGAAAC ATCCACAGGA 1500
ATAAACATTA CAACGGTGGC TATTCCATTG GTGCTCCTTG TTGTCCTGGT CTTTGCTGGA 1560
ATGGGGATCT TTGCAGCCTT TAGAAAGAAG AAGAAGAAAG GAAGTCCGTA TGβATCAGCA 1620
GAGGCTCAGA AAACAGACTG TTGGAAGCAG ATTAAATATC CCTTTGCCAG ACATCAGTCA 1680
GCTGAGTTTA CCATCAGCTA TGATAATGAG AAGGAGATGA CACAAAACTT AGATCTCATC 1740
ACAAGTβATA TGGCAGGTTA A 1761
Seq ID NO: C138 DNA Sequence
Nucleic Acid Accession ft: FGENESH predicted
Coding sequence: 1..2310
1 11 21 31 41 51
I I I I I I
ATGTTCCAGC GGCAGGAAAG ATTTCTTGAC TTATCTTCAG CTGAAGCAGT GGCAGCTTGG 60
ATATTACATC AACATCCTGA CATTATTAAC AAAGGTGATG GCTGTGGACA CCTAGTGACT 120
TATCAGGATA GTGGCACAAT GACATCTAAG AATTATCCCG GGACCTACCC CAATCACACT 180
GTTTGCGAAA AGACAATTAC AGTACCAAAG GGGAAAAGAC TβATTCTGAG GTTGGGAGAT 240
TTGGATATCG AATCCCAGAC CTGTβCTTCT GACTATCTTC TCTTCACCAG CTCTTCAGAT 300
CAATATGGAA TβCAGAAGGA GGAGGAβACA βAAGTGCTTT GTCTTTCAGT GGCTGGCGCT 360
CAGAGAGTGG ACATTCCTGT βCAGCTGTTG CCCAβCTTCC TGGAAGGβTβ GAAGGGTCAT 420
GCTGATGCAA GAGGTCCATA CTGTGGAAGT ATGACTGTTC CCAAAGAACT CTTGTTGAAG 480
ACAAGTGAAG TAACCGTCCG CTTTGAβAGT GGATCCCACA TTTCTGGCCG GGGTTTTTTG 540
CTGACCTATG CGAGCAGCGA CCATCCAGAT TTAATAACAT GTTTGGAACG AGCTAGCCAT 600
TATTTGAAGA CAGAATACAG CAAATTCTGC CCAGCTGβTT GTAGAGACGT AGCAGGAGAC 660
ATTTCTGGGA ATATGGTAGA TGGATATAGA GATACCTCTT TATTβTβCAA AGCTGCCATC 720
CATGCAGGAA TAATTGCTGA TGAACTAGGT GGCCAGATCA CTGTGCTTCA GCGCAAAGGG 780
ATCAGTCGAT ATGAAGGGAT TCTGGCCAAT GGTGTTCTTT CGAGGGATGG TTCCCTGTCA 840
GACAAGCGAT TTCTGTTTAC CTCCAATGGT TGCAGCAGAT CCTTGAGTTT TGAACCTGAC 900
GGGCAAATCA GAGCTTCTTC CTCATGGCAG TCGGTCAATG AGAGTGGAGA CCAAGTTCAC 960 TGGTCTCCTG GCCAAGCCCG ACTTCAGGAC CAAGGCCCAT CATGGGCTTC GβGCGACAGT 1020
AGCAACAACC ACAAACCACG AGAGTGGCTG GAGATCGATT TGGGβGAGAA AAAGAAAATA 1080
ACAGGAATTA GGACCACAGG ATCTACACAG TGGAACTTCA ACTTTTATGT TAAGA6TTTT 1140
GTGATGAACT TCAAAAACAA TAATTC AAG TGGAAGACCT ATAAAGGAAT TGTGAATAAT 1200
GAAGAAAAGG TGTTTCAGGG TAACTCTAAC TTTCGGβACC CAGTGCAAAA CAATTTCATC 1260
CCTCCCATCG TGGCCAGATA TGTGCGGGTT GTCCCCCAGA CATGGCACCA GAββATAGCC 1320
TTGAAGGTGG AGCTCATTGβ TTGCCAGATT ACACAAGGTA ATGATTCATT βGTβTβecGC 1380
AAGACAAGTC AAAGCACCAG TGTTTCAACT AAGAAAGAAG ATGAGACAAT CACAAGGCCC 1440
ATCCCCTCGG AAGAAACATC CACAGATGCC ATGCCAGTGC AGATTGTCGG AGACCATACC 1500
CAGATGATCT CACAAAGGGA GAATCTGβGA CCTGATGAGG GCAAAATACC TTTTAAAGGC 1560
ACAGCGGAAA GCATGGTTAG AGTAGTGTTT GCTGTTGTGG TTAATGACCT TGGCATGCTG 1620
TTCTTAGCAC ACACACCTGA GGAGGACATT GATCACTACT GTTGGAAGCA GATTAAATAT 1680
CCCTTTGCCA GACATCAGTC AGCTGAGTTT ACCATCAGCT ATGATAATGA GAAGGAGATG 1740
ACACAAAAGT TAGATCTCAT CACAAGTGAT ATGGCAGATT ACCAGCAGCC CCTCATGATT 1800
GGCACCGGGA CAGTCACGAG GAAGGGCTCC ACCTTCCGGC CCATGGACAC GGATGCCGAG 1860
GAGGCAGGGG TGAGCACCGA TGCCGGCGGC CACTATGACT GCCCGCAGCG GGCCGGCCGC 1920
CACGAGTACG CGCTGCCCCT GGCGCCCCCG GAGCCCGAGT ACGCCACGCC CATCGTGGAG 1980
CββCACGTGC TGCGCGCCCA CACGTTCTCT GCGCAGAGCG GCTACCGCGT CCCAGGGCCC 2040
CAGCCCGGCC ACAAACACTC CCTCTCCTCG GGCGGCTTCT CCCCCGTAGC GGGTGTGGGC 2100
GCCCAGGACG GAGACTATCA AAGGCCACAC AGCGCACAGC CTGCGGACAβ GGGCTACGAC 2160
CGGCCCAAAG CTGTCAGCGC CCTCGCCACC GAAAGCGGGC ACCCTGACTC TCAGAAGCCC 2220
CCAACGCATC CCGGGACGAG TGACAGCTAT TCTGCCCCCA GAGACTGCCT CACACCCCTC 2280
AACCAGACGG CCATGACTGC CCTTTTGTGA 2310
Seq ID NO: C139 DNA Sequence
Nucleic Acid Accession #: NM_004616.2
Coding sequence: 180..893
11 21 31
AGTGCCCCAG GAGCTATGAC AAGCAAAGGA ACATACTTGC CTGGAGATAG CCTTTGCGAT 60
ATTTAAATGT CCGTGβATAC AGAAATCTCT βCAGβCAAGT TGCTCCAGAG CATATTGCAG 120
GACAAGCCTG TAACGAATAG TTAAATTCAC GGCATCTGGA TTCCTAATCC TTTTCCGAAA 180
TGβCAββTβT 6AGTGCCTGT ATAAAATATT CTATGTTTAC CTTCAACTTC TTGTTCTGGC 240
TATβTGGTAT CTTGATCCTA GCATTAGCAA TATGGGTACG AGTAAGCAAT GACTCTCAAG 300
CAATTTTTGG TTCTGAAGAT GTAββCTCTA GCTCCTACGT TGCTGTGGAC ATATTGATTG 360
CTGTAGβTβC CATCATCATG ATTCTGGβCT TCCTGGGATG CTGCGGTGCT ATAAAAGAAA 420
GTCGCTGCAT GCTTCTGTTG TTTTTCATAG GCTTGCTTCT GATCCTGCTC CTGCAGGTGG 480
CGACAGGTAT CCTAGβAGCT GTTTTCAAAT CTAAGTCTGA TCGCATTGTG AATGAAACTC 540
TCTATGAAAA CACAAAGCTT TTβAβCβCCA CAGGGGAAAG TGAAAAACAA TTCCAGGAAG 600
CCATAATTβT βTTTCAACAA GAGTTTAAAT GCTGCGGTTT GGTCAATGGA GCTGCTGATT 660
GGGGAAATAA TTTTCAACAC TATCCTGAAT TATGTGCCTG TCTAGATAAG CAGAGACCAT 720 βCCAAAβCTA TAATGGAAAA CAAGTTTACA AAGAGACCTG TATTTCTTTC ATAAAAGACT 780
TCTTββCAAA AAATTTGATT ATAGTTATTG GAATATCATT TGGACTGGCA GTTATTGAGA 840
TACTGGGTTT GGTGTTTTCT ATGGTCCTGT ATTGCCAGAT CGGGAACAAA TGAATCTGTG 900
GAT6CATCAA CCTATCGTCA GTCAAACCCC TTTAAAATCT TGCTTTGGCT TTGTAAATTT 960
AAATATGTAA GTGCTATATA AGTCAGGAGC AGCTGTCTTT TTAAAATGTC TceβcTAβcT 1020
AGACCACAGA TATCTTCTAG ACATATTGAA CACATTTAAG ATTTGAGGGA TATAAGβGAA 1080
AATGATATGA ATGTGTATTT TTACTCAAAA TAAAAGTAAC TGTTTACGTT AAAAAAAAAA 1140
AAAAAAAAAA AAAAAAAAA 1159
Seq ID NO: C140 DNA Sequence
Nucleic Acid Accession #: NM_004617.2
Coding sequence : 232..840
11 21 31
CTTCAGβTCA GGGAGAATGT ATAAATGTCC ATTGCCATCG AGGTTCTβCT ATTTTTGAGA 60
AGCTGAAβCA ACTCCAAGGA CACAGTTCAC AGAAATTTGG TTCTCAβCCC CAAAATACTG 120
ATTGAATTGG AGACAATTAC AAGGACTCTC TGGCCAAAAA CCCTTGAAGA GGCCCCGTGA 180
AGGAGGCAGT GAGGAGCTTT TGATTGCTGA CCTGTGTCGT ACCACCCCAG AATGTGCACT 240
GGGGGCTCTG CCAGATGCCT GGGGGGGACC CTCATTCCCC TTGCTTTTTT TGGCTTCCTG 300
GCTAACATCC TGTTATTTTT TCCTGGAGGA AAAGTGATAβ ATGACAACGA CCACCTTTCC 360
CAAβAGATCT GGTTTTTCGG AGGAATATTA GGAAGCβGTG TCTTGATGAT CTTCCCTGCG 420
CTGGTGTTCT TGGGCCTGAA GAACAATGAC TGCTGTGββT GCTGCGGCAA CGAGGGCTGT 480
GGGAAGCGAT TTGCGATGTT CACCTCCACG ATATTTGCTG TGGTTGGATT CTTGGGAGCT 540
GGATACTCβT TTATCATCTC AGCCATTTCA ATCAACAAGG GTCCTAAATG CCTCATGGCC 600
AATAGTACAT GGGGCTACCC CTTCCACGAC GGGGATTATC TCAATGATGA GGCCTTATGG 660
AACAAGTGCC GAGAGCCTCT CAATGTGGTT CCCTGGAATC TGACCCTCTT CTCCATCCTG 720
CTGGTCGTAG GAGGAATCCA GATGGTTCTC TGCGCCATCC AGGTGGTCAA TGGCCTCCTG 780
GGGACCCTCT GTGGGGACTG CCAGTGTTGT GGCTGCTGTG GGGGAGATGG ACCCGTTTAA 840
ACCTCCGAGA TGAGCTGCTC AGACTCTACA GCATGACGAC TACAATTTCT TTTCATAAAA 900
CTTCTTCTCT TCTTGGAATT ATTAATTCCT ATCTGCTTCC TAGCTGATAA AGCTTAGAAA 960
AGGCAGTTAT TCCTTCTTTC CAACCAGCTT TGCTCGAGTT AGAATTTTGT TATTTTCAAA 1020
TAAAAAATAG TTTGGCCACT TAACAAATTT GATTTATAAA TCTTTCAAAT TACTTCCTTT 1080
TTAGAATTTA CCAACAGGTT CAAAGCATAC TTTTCATGAT TTTTTTATTA CAAATGTAAA 1140
ATGTATAAAG TCACATGTAC TGCCATACTA CTTCTTTGTA TATAAAGATG TTTATATCTT 1200
TGGAAGTTTT ACATAAATCA AAGβAAGAAA eCACATTTAA AATGAGAAAC TAAGACCAAT 1260
TTCTGTTTTT AAGAGβAAAA AGAATGATTG ATGTATCCTA AGTATTGTTA TTTGTTGTCT 1320
TTTTTTGCTG CCTTGCTTGA GTTGCTTGTG ACTGATCTTT TGAGGCTGTC ATCATGGCTA 1380
GGGTTCTTTT ATGTATGTTA AATTAAAACC TGAATTCAGA GGTAACGT 1428
Seq ID NO: C141 DNA Sequence
Nucleic Acid Accession ft: NM 002381.2 Coding sequence : 64 . .1524
31
AAATCCGAGC CTCGCGTGGG CTCCTGGCCC CCGACGGACA CCACCAGGCC CACGGAGCCC 60
ACCATGCCGC GCCCGβCCCC CGCGCβCCGC CTCCCGGGAC TCCTCCTGCT GCTCTGGCCG 120
CTβCTGCTGC TGCCCTCCGC CβCCCCCGAC CCCGTGGCCC GCCCGGGCTT CCGGAGGCTG 180
GAGACCCGAG GTCCCGGGGG CAGCCCTGGA CGCCCCCCCT CTCCTGCGGC TCCCGACGGC 240
GCGCCCGCTT CCGGGACCAG CGAGCCTGGC CβCβCCCGCG GTGCAGGTGT TTGCAAβAβC 300
AGACCCTTGG ACCTGβTGTT TATCATTGAT AGTTCTCGTA GCGTACGGCC CCTGβAATTC 360
ACCAAAGTGA AAACTTTTGT CTCCCGGATA ATCGACACTC TGGACATTGG βCCAβCCGAC 420
ACGCGGGTGG CAGTGGTGAA CTATGCTAGC ACTGTGAAGA TCGAGTTCCA ACTCCAGGCC 480
TACACAGATA AGCAGTCCCT GAAGCAGGCT GTGGGTCGAA TCACACCCTT CTCAACAGGC 540
ACCATGTCAG GCCTAGCCAT CCAGACAGCA ATGGACGAAG CCTTCACAGT GGAGβCAGβG 600
GCTCGAGAGC CCTCTTCTAA CATCCCTAAG GTGGCCATCA TTGTTACAGA TGGGAββCCC 660
CAGGACCAGβ TGAATGAAGT GGCGGCTCGG GCCCAAGCAT CTGGTATTGA GCTCTATGCT 720
GTGGGCβTββ ACCGGGCAGA CATGGCGTCC CTCAAGATGA TGGCCAGTGA GCCCCTAβAG 780
GAGCATGTTT TCTACGTGGA GACCTATGGG GTCATTGAGA AACTTTCCTC TAGATTCCAG 840
GAAACCTTCT GTGCGCTGGA CCCCTGTGTG CTTGGAACAC ACCAGT6CCA GCACGTCTGC 900
ATCAGTGATβ GGGAAGGCAA GCACCACTGT GAGTGTAGCC AAGGATACAC CTTGAATGCC 960 βACAAGAAAA CGTGTTCAGC TCTTGATAGG TGTGCTCTTA ACACCCACGG ATGTGAGCAC 1020
ATCTGTGTGA ATGACAGAAG TGGCTCTTAT CATTGTGAGT GCTATGAAGG TTATACCTTG 1080
AATGAAGACA GGAAAACTTG TTCAGCTCAA GATAAATGTG CTTTGGGTAC CCATGGGT6T 1140
CAGCACATTT GTGTGAATGA CAGAACAGGβ TCCCATCATT GT6AATGCTA TGAGGGCTAC 1200
ACTCTGAATG CAGATAAAAA AACATGTTCA GTCCβTβACA AGTGTGCCCT AGGCTCTCAT 1260
GGTTGCCAGC ACATTTGTGT GAβTβATGGG GCCGCATCCT ACCACTGTGA TTGCTATCCT 1320
GGCTACACCT TAAATGAGGA CAAGAAAACA TGTTCAGCCA CTGAGGAAGC ACGAAGACTT 1380
GTTTCCACTβ AAGATGCTTG TGGATGTGAA GCTACACTGG CATTCCAGβA CAAGβTCAβC 1440
TCGTATCTTC AAAGACTGAA CACTAAACTT GATGACATTT TGGAGAAGTT GAAAATAAAT 1500
GAATATGGAC AAATACATCG TTAAATTGCT CCAATTTCTC ACCTGAAAAT GTGGACAGCT 1560
TGGTGTACTT AATACTCATG CATTCTTTTG CACACCTGTT ATTGCCAATG TTCCTGCTAA 1620
TAATTTGCCA TTATCTGTAT TAATGCTTβA ATATTACTββ ATAAATTGTA TGAAGATCTT 1680
CTGCAGAATC AGCATGATTT TTCCAAGGAA ATACATATGC AGATACTTAT TAAGAGCAAA 1740
CTTTAGTGTC TCTAAGTTAT GACTGTGAAA TGATTGGTAG GAAATAGAAT βAAAAβTTTA 1800
GTGTTTCTTT ATCTACTAAT TGAβCCATTT AATTTTTAAA TGTTTATATT AβATAACCAT 1860
ATTCACAATG GAAACTTTAG GTCTAGTTTC TTTTGATAGT ATTTATAATA TAAATCAATC 1920
TTATTACTGA GAGTGCAAAT TGTACAAGGT ATTTACACAT ACAACTTCAT ATAACTGAGA 1980
TGAATGTAAT TTTGAACTGT TTAACACTTT TTGTTTTTTβ CTTATTTTβT TGGAGTATTA 2040
TTGAAGATGT GATCAATAGA TTGTAATACA CATATCTAAA AATAGTTAAC ACAGATCAAG 2100
TGAACATTAC ATTGCCATTT TTAATTCATT CTCGTCTTTG AAAGAAATGT ACTACTAAAG 2160
AGCACTAGTT GTGAATTTAG GGTGTTAAAC TTTTTACCAA GTACAAAAAT CCCAAATTCA 2220
CTTTATTATT TTGCTTCAGG ATCCAAGTGA CAAAGTTATA TATTTATAAA ATTGCTATAA 2280
ATCGACAAAA TCTAATGTTG TCTTTTTAAT GTTAGTGATC CACCTβCCTC AGCCTCCCAA 2340
AGTGCTGGGA TTACAGGCTT GAAAGTCTAA CTTTTTTTTA CTTATATATT TGATACATAT 2400
AATTCTTTTG GCTTTGAAAC TTGCAACTTT GAGAACAAAA CAGTCCTTTA AATTTTGCAC 2460
TGCTCAATTC TGTTTTTCGT TTGCATTGTC TTTAATATAA TAAAAGTTAT TACCTTTACA 2520
TATTATCATG TCTATTTTTG ATGACTCATC AATTTTGTCT ATTAAAGATA TTTCTTTAAA 2580
TTAAAAAAAA AAAAAAAAA 2599
Seq ID NO: C142 DNA Sequence
Nucleic Acid Accession tf: NM_016639.1
Coding sequence: 40..429
60
120
Figure imgf001290_0001
180
AAGTGCATGG ACTGCGCGTC TTGCAGGGCG CGACCGCACA GCβACTTCTβ CCTββGCTGC 240
GCTGCAGCAC CTCCTGCCCC CTTCCGGCTG CTTTGGCCCA TCCTTGGGGG CGCTCTGAGC 300
CTGACCTTCG TGCTGGGGCT GCTTTCTGGC TTTTTGGTCT GGAGACGATG CCGCAGGAGA 360
GAGAAGTTCA CCACCCCCAT AGAGGAGACC βGCGGAGAGG GCTGCCCAGC TGTGGCGCTG 420
ATCCAGTGAC AATGTGCCCC CTGCCAGCCG GGGCTCGCCC ACTCATCATT CATTCATCCA 480
TTCTAGAGCC AGTCTCTGCC TCCCAGACGC GGCGGGAGCC AAGCTCCTCC AACCACAAGG 540
GGGGTGGGββ GCGGTGAATC ACCTCTGAGG CCTGGGCCCA GGGTTCA6GG GAACCTTCCA 600
AGGTGTCTGG TTGCCCTGCC TCTGβCTCCA GAACAGAAAG GGAGCCTCAC βCTGGCTCAC 660
ACAAAACAGC TGACACTGAC TAAGGAACTG CAGCATTTGC ACAGGGβAβG GGβGTGCCCT 720
CCTTCCTTAG GACCTGGGGG CCAGGCTGAC TTGGGGGGCA GACTTGACAC TAGGCCCCAC 780
TCACTCAGAT GTCCTGAAAT TCCACCACGG GGGTCACCCT GGGGGGTTAG GGACCTATTT 840
TTAACACTAG GGGCTGGCCC ACTAGGAGGG CTGGCCCTAA GATACAGACC CCCCCAACTC 900
CCCAAAGCGG GGAGGAGATA TTTATTTTGG GGAGAβTTTG GAGGGGAGGG AGAATTTATT 960
AATAAAAGAA TCTTTAACTT TAAAAAAAAA AAAAAAAA 998
Seq ID NO: C143 DNA Sequence Nucleic Acid Accession #: NM_001819 Coding sequence: 113..2146
11 21 31 41 51
CCAGGAGGCA CGCTGGTTTT CCGGGGCCGC TCCATCGCGC CTTCCTCCTG CGCCTCGCTT 60
CTCCGGTCCA GCCGCCATCT TCCTTTCCGC ACAGGGGCCG CCGAGCGGGG CCATGCAGCC 120
AACGCTGCTT CTCAGCCTCC TGGGAGCCGT βGGGCTGGCG GCTGTCAATT CCATGCCAGT 180
GGATAACAGG AACCACAATG AAGGAATGGT GACTCGCTGC ATCATTGAGG TCCTCTCAAA 240 TGCCTTGTCG AAGTCCAGCG CTCCACCCAT CACCCCTGAG TGCCGCCAAG TCCTGAAGAC 300
GAGTAGAAAA GACGTCAAAG ACAAAGAGAC AACTGAAAAT GAAAACACAA AGTTTGAAGT 360
AAGATTGTTA AGAGACCCAG CTGATGCCTC GGAAGCCCAC GAGTCCTCCA GCAGGGGAGA 420
GGCAGGAGCC CCAGGGGAGG AGGACATCCA AGGCCCAACA AAGGCAGACA CAGAβAAATG 480
GGCAGAGGGA GGCGGGCACA GCCGAGAGCG AGCGGATGAG CCCCAGTGGA GCCTCTATCC 540
CTCCGACAGC CAAGTCTCTG AAGAAGTGAA GACACGCCAT TCTGAGAAGA βCCAGAGAGA 600
GGATGAβGAG GAGGAGGAGG GAGAGAACTA TCAAAAAGGG GAGCGAGGGG AAGATAGCAG 660
TGAAGAGAAA CACCTTGAAG AGCCAGGAGA GACACAAAAC GCTTTTCTCA ATGAAAGAAA 720
GCAGGCTTCA GCTATAAAAA AAGAGGAβTT AGTGGCCAGA TCGGAAACAC ATGCTGCCGG 780
GCATTCTCAG GAGAAGACAC ATAβCCβAGA GAAGAβTAGC CAGGAGAβTG GAGAGGAGGC 840
AGββAβCCAG GAGAATCACC CCCAGβAβTC TAAAGGCCAA CCCCGAAGCC AGGAAGAATC 900
TGAGβAAGGT GAGGAAGATG CCACCTCTGA GGTGGACAAA CGACGCACGA GGCCCAGACA 960
CCACCACGGG AGGAGCAGGC CCGACAGGTC CTCTCAAGGA GGGAGTCTTC CCTCTGAGGA 1020
AAAGββACAC CCCCAGGAGG AATCTGAGGA GTCAAACGTC AGCATGGCCA GTTTAGGGGA 1080
AAAGAGGGAC CACCATTCAA CCCACTACAG GGCTTCAGAG βAAGAACCTG AATATββAβA 1140
AGAAATAAAG GGTTATCCAG GCGTCCAGβC CCCTGAGGAC CTGGAGTβGG AβCβCTATAG 1200
GββCAGAGGA AGTGAAGAAT ACAβββCTCC AAGACCTCAG AGTGAGGAGA GTTGβGATGA 1260
GGAGβACAAG AGAAACTACC CCAGCTTAGA GCTTGATAAG ATGβCACATG GATATGGTGA 1320
AGAAAGTGAG GAAGAGAGGG GCCTTGAβCC GGGAAAGGGA CGCCATCACA GAGGCAGGGG 1380
AGGGGAGCCA CGTGCCTATT TCATGTCTGA CACCAGAGAA GAGAAAAGGT TCTTGGGTGA 1440
AGβACACCAC CGTGTCCAAG AAAACCAGAT GGACAAGGCA AGGAGGCATC CACAAGGTGC 1500 βTββAAAβAG CTGGACAGAA ATTATCTCAA CTACGGTGAG GAAGGAGCCC CACβGAAGTG 1560
GCAGCACCAG GGAGACCTGC AGGACACTAA AGAAAACAGG GAGGAAGCTA GGTTTCAAGA 1620
TAAACAATAT AGCTCCCATC ACACAGCTGA AAAGAGGAAG AGATTAGGGβ AACTGTTCAA 1680
CCCATACTAC GACCCTCTCC AGTGGAAGAG CAGCCATTTT GAAAGAAGAG ACAACATGAA 1740
TGACAATTTT CTCGAGGβTG AGGAGGAAAA TGAGCTGACC TTGAACGAGA AGAATTTCTT 1800
CCCAGAATAC AACTATGACT GGTGGGAGAA AAAGCCCTTC TCTGAGGATG TGAACTGGGG 1860
GTATGAGAAG AGAAACCTCG CCAGGβTCCC CAAGCTGGAC CTGAAAAGGC AATATGACAG 1920
Q3TGGCCCAA CTGGACCAGC TCCTTCACTA CAG8AAGAAG TCAGCTGAGT TTCCAGACTT 1980
CTATGATTCT GAGGAGCCGG TGAGCACCCA CCAGGAGGCA GAAAATGAAA AGGACAGβGC 2040
TGACCAGACA GTCCTβACAG AGGACGAGAA AAAAGAACTC GAAAACTT6G CTGCAATGGA 2100
TTTGGAACTA CAGAAGATAG CTGAGAAATT CAGCCAAAGG ββCTGACTGT CATTGGAGCG 2160
GTGGGCACTG TTAAGAAGCA GCCATCACAT GATCTGTTTT TCACCACTTC ACTGAAAGAC 2220
ACCATTTATA TACCCAAGGG CAGAAAGTAβ AACTTACTAT TCATTAAATG TTTGACACAA 2280
TTGβAATTGT CTTTAATTTC TGTCAGAATG CTATTGAAAA TGTGAATTβC ATGACTTGTA 2340
GCATATTCTT TTCTGCAAAA TAGACATATT AACATGCTTA TGACAATGAC TGTGCTACTG 2400
TCTTTGGAAA AATGTTTGTC TCAGTTGβAA ATAATAAAAG ATTCACCTGA GACC 2454
Seq ID NO: C144 DNA Sequence Nucleic Acid Accession #: XM_093082.1 Coding sequence: 93..1988
1 11 21 31 41 51
1 1 | 1 | 1 | 1 | 1 I 1
CTTCTTGTGG TAGGGACCTC TCCTCAGTAT TTGAAACTAA CCAGCATCTG ACAGATTTCG 60
AATTTGTAAA AAATACCCTC GAAGATTCAG GAATGAAGCT TCTGTGTGAA GβATTAAAAC 120
AGCCCAACTG TGTATTACAG ACATTGAGGT GGTACCGGTG CCTTATCTCT TCTGCTTCTT 180
GTGGGGCTCT AGCAβCTGTT CTTAGCACCA GTCAGTGGCT CACTGAACTG GAATTTAGTG 240
AGACAAAACT GβAAGCTTCA GCTTTGAAAT TGCTCTATGG AGGCTTAAAA GATCCAAATT 300
GCAAATTACA GAAGCTCAAC TTGCAGTTTT CTTTATCTGT AACCCCTGCA AAACTTCCAG 360
TTGGAATGGT TGGAAATTGT TCTGGTTTCT CGβGATCATT GβTGCAATCT CATTTTGGCT 420
ACTGTCAGGA CAGTTCTTTC AAATGTGATC TTTGTAAGCT GCTCTGβCCT TCCACCAGAG 480
TTGCTβCTGC AAAGGATTGT GGGAGTCCTA AGTCCTTCCT ATCAGAAG6G CTGAACTGGG 540
CAGGAAGACT TGAGGCAGTG GAGGAGGTTT TGGGβTTGGG GGTGCTTGTA CAGCCCGGTG 600
ACCCAGCATC TCAGGGTGGG GGGCATTGTG AAAACTATGG GTCTTTTAGA GACTTGGTGG 660
ACTTAGAAGT CAAGGCAGAA CCAAGCCTβA GAAAAGGTGG TATGGATCTC CAGAGACCCA 720
CCCTACAAGT TGTCCTCCTT TβCAAAATCT TCTCCGTCAA ACTATTTCTC TTTATTGCAT 780
TGCCTAATTC TCCTGCTCAG GTTAGTGTGG TGCAAGTGAC CATCCCAGAC GGTTTCGTGA 840
ACGTGACTGT TββATCTAAT GTCACTCTCA TCTGCATCTA CACCACCACT GTGGCCTCCC 900
GAGAACAGCT TTCCATCCAG TGGTCTTTCT TCCATAAGAA GGAGATβGAG CCAATTTCTT 960
CTCCTTGGGA GGAGGGGAAG TGGCCAGATG TTGAGGCTGT GAAGGGCACT CTTGATGGAC 1020
AGCAGGCTGA ACTCCAGATT TACTTTTCTC AAβGTGGACA AGCTGTAGCC ATCGGGCAAT 1080
TTAAAGATCG AATTACAGGG TCCAACGATC CAGGTAATGC ATCTATCACT ATCTCeCATA 1140
TGCAGCCAGC AGACAGTGGA ATTTACATCT GCGATGTTAA CAACCCCCCA GACTTTCTCG 1200 eCCAAAACCA AGGCATCCTC AACGTCAGTG TGTTAGTGAA ACCTTCTAAG CCCCTTTGTA 1260
GCGTTCAAGG AAGACCAGAA ACTGGCCACA CTATTTCCCT TTCCTGTCTC TCTGCGCTTG 1320
GAACACCTTC CCCTGTβTAC TACTGGCATA AACTTGAGGG AAGAGACATC GTGCCAGTGA 1380
AAGAAAACTT CAACCCAACC ACCGGGATTT TGGTCATTGG AAATCTGACA AATTTTGAAC 1440
AAGGTTATTA CCAGTGTACT GCCATCAACA GACTTGGCAA TAGTTCCTGC GAAATCGATC 1500
TCACTTCTTC ACATCCAGAA GTTGβAATCA TTGTTGGGGC CTTGATTGGT AGCCTβGTAβ 1560
GTGCCGCCAT CATCATCTCT GTTGTGTGCT TCGCAAGGAA TAAGGCAAAA GCAAAGβCAA 1620
AAGAAAGAAA TTCTAAGACC ATCGCGGAAC TTGAGCCAAT GACAAAGATA AACCCAAGGG 1680
GAGAAAGCGA AGCAATGCCA AGAGAAGACG CTACCCAACT AGAAGTAACT CTACCATCTT 1740
CCATTCAT6A GACTGGCCCT GATACCATCC AAGAACCAGA CTATGAGCCA AAGCCTACTC 1800
AGGAGCCTGC CCCAGAGCCT GCCCCAGGAT CAGAGCCTAT GGCAGTGCCT GACCTTGACA 1860
TCCAGCTGGA GCTGGAGCCA GAAACGCAGT CGGAATTGGA GCCAGAGCCA GAGCCAGAGC 1920
CAGAGTCAGA βCCTGGGGTT GTAGTTGAGC CCTTAAGTGA AGATGAAAAG βGAGTGGTTA 1980
AGGCATAG 1988
Seq ID NO: C145 DNA Sequence
Nucleic Acid Accession # : FGENESH predicted
Coding sequence : 1. .1242
11 21 31 ATGGTGTTCG CATTTTGGAA GβTCTTTCTG ATCCTAAGCT GCCTTGCAGβ TCAGGTTAGT 60
GTβGTGCAAG TGACCATCCC AGACGGTTTC GTGAACGTGA CTGTTGGATC TAATGTCACT 120
CTCATCTGCA TCTACACCAC CACTGTβGCC TCCCGAGAAC AGCTTTCCAT CCAβTββTCT 180
TTCTTCCATA AGAAGGAGAT GGAGCCAATT TCTTCTCCTT GGGAGGAGGβ GAAGTGGCCA 240
GATGTTGAGG CTGTGAAGGG CACTCTTGAT GGACAGCAGG CTGAACTCCA GATTTACTTT 300
TCTCAAGGTG GACAAGCTGT AGCCATCGGG CAATTTAAAC ATCGAATTAC AGGGTCCAAC 360
GATCCAGGTA ATGCATCTAT CACTATCTCG CATATGCAGC CAGCAGACAG TGGAATTTAC 420
ATCTGCGATG TTAACAACCC CCCAGACTTT CTCGGCCAAA ACCAAGGCAT CCTCAACGTC 480
AGTGTGTTAG TGAAACCTTC TAAGCCCCTT TGTAGCGTTC AAGGAAGACC AGAAACTGGC 540
CACACTATTT CCCTTTCCTG TCTCTCTGCG CTTGGAACAC CTTCCCCTGT GTACTACTGG 600
CATAAACTTG AGGGAAGAGA CATCGTGCCA GTGAAAGAAA ACTTCAACGC AACCACCGGG 660
ATTTTGGTCA TTGGAAATCT GACAAATTTT GAACAAGGTT ATTACCAGTG TACTGCCATC 720
AACAGACTTG GCAATAGTTC CTGCGAAATC GATCTCACTT CTTCACATCC AGAAGTTGGA 780
ATCATTGTTG GGGCCTTGAT TGGTAGCCTG GTAGGTGCCG CCATCATCAT CTCTGTTβTG 840
TGCTTCGCAA GGAATAAGGC AAAAGCAAAG GCAAAAGAAA GAAATTCTAA GACCATCGCG 900
GAACTTGAβC CAATGACAAA GATAAACCCA AGGGGAGAAA GCGAAGCAAT GCCAAGAGAA 960 βACβCTACCC AACTAGAAGT AACTCTACCA TCTTCCATTC ATGAGACTGG CCCTGATACC 1020
ATCCAA6AAC CAGACTATGA GCCAAAGCCT ACTCAGGAGC CTGCCCCAGA GCCTGCCCCA 1080
GGATCAGAGC CTATGGCAGT GCCTGACCTT GACATCGAGC TGGAGCTGGA GCCAGAAACG 1140
CAGTCGGAAT TGGAGCCAGA GCCAGAGCCA GAGCCAGAGT CAGAGCCTGβ GGTTβTAGTT 1200
GAβCCCTTAA GTGAAGATGA AAAGGGAGTG GTTAAGGCAT AG 1242
Seq ID NO : C146 DNA Sequence Nucleic Acid Accession ft : NM_003020.1
Coding sequence : 29. .664
11 21 31
CGCTCCTCGG GCTGCCCCTC GGTTGACAAT GGTCTCCAGG ATGGTCTCTA CCATGCTATC 60
TGβCCTACTβ TTTTβecTββ CATCTGGATG GACTCCAGCA TTTGCTTACA GCCCCCGGAC 120
CCCTGACCGG GTCTCAGAAG CAGATATCCA GAβGCTGCTT CATGGTGTTA TGGAGCAATT 180
GGGCATTGCC AGGCCCCGAG TGGAATATCC AGCTCACCAG GCCATGAATC TTGTG6GCCC 240
CCAGAGCATT GAAGβTGGAβ CTCATGAAGG ACTTCAGCAT TTGGGTCCTT TTGGCAACAT 300
CCCCAACATC GTGGCAGAGT TGACTGGAGA CAACATTCCT AAGGACTTTA GTGAGGATCA 360
GGGGTACCCA GACCCTCCAA ATCCCTGTCC TGTTGGAAAA ACAGATGATG GATGTCTAGA 420
AAACACCCCT GACACTGCAG AGTTCAGTCβ AGAGTTCCAβ TTGCACCAGC ATCTCTTTGA 480
TCCGGAACAT GACTATCCAG βCTTGGGCAA GTβGAACAAG AAACTCCTTT ACGAGAAGAT 540
GAAGGGAGGA GAGAGACGAA AGCGβAβGAG TGTCAATCCA TATCTACAAG GACAGAGACT 600
GGATAATGTT GTTGCAAACA AGTCTGTCCC CCATTTTTCA GATGAGGATA AGGATCCAGA 660
GTAAAGAGAA GATGCTAGAC βAAAACCCAC ATTACCTGTT AGGCCTCAGC ATGGCTTATG 720
TGCACGTGTA AATGGAGTCC CTβTβAATβA CAGCATGTTT CTTACATAGA TAATTATGGA 780
TACAAAGCAG CTGTATGTAG ATAGTGTATT GTCTTCACAC CGATGATTCT GCTTTTTGCT 840
AAATTAGAAT AAGAGCTTTT TTGTTTCTTβ GGTTTTTAAA ATGTGAATCT GCAATGATCA 900
TAAAAATTAA AATGTGAATG TCAACAATAA AAAGCAAGAC TATGAAAGβC TCAGATTTCT 960
TGCAGTTTAA AATGGTGTCT GAGGTTGTAC TATTTTGGCC AAGTCTGTAG AAAGCTGTCA 1020
TTTGATTTTG ATTATGTAGT TCATCCAGCC CTTGGGCATT GTTATACACC AGTAAAGAAβ 1080
GCTGTACTCA AGAGGAGGAG CTGACACATT TCACTTGGCT GCGTCTTAAT AAACATβAAT 1140
GCAAGCATTG GC 1152
Seq ID NO : C147 DNA Sequence Nucleic Acid Accession ff : NM_024021 . Coding sequence : 144. .806
11 21 31 51
AACATTCCTG CAAATGGTTT CAATATATGC AGATGTCTCG ATATAGGAAT GAAATTACGT 60
CTTTGGAACA ACTTAAATAA GTCAAATATA CTTGGAGCTT TAAAAATTAA AAGGAGAGAG 120
ATTCGAGCAC CTTTTCTGCT GCCATGACAA CCATGCAAβG AATGGAACAG GCCATGCCAG 180
GGGCTGGCCC TGGTGTGCCC CAGCTGGGAA ACATGGCTGT CATACATTCA CATCTGTGGA 240
AAGGATTGCA AGAGAAGTTC TTGAAGGGAG AACCCAAAGT CCTTGGGGTT GTGCAGATTC 300
TGACTGCCCT GATGAGCCTT AGCATGGGAA TAACAATGAT GTGTATGGCA TCTAATACTT 360
ATGGAAGTAA CCCTATTTCC GTGTATATCG GGTACACAAT TTGGGGGTCA GTAATGTTTA 420
TTATTTCAGG ATCCTTGTCA ATTGCAGCAβ GAATTAβAAC TACAAAAGGC CTGGTCCGAG 480
GTAGTCTAGG AATGAATATC ACCAGCTCTG TACTGGCTβC ATCAGGGATC TTAATCAACA 540
CATTTAGCTT GGCGTTTTAT TCATTCCATC ACCCTTACTG TAACTACTAT GGCAACTCAA 600
ATAATTGTCA TGGGACTATβ TCCATCTTAA TGGGTCTGGA TGGCATGCTG CTCCTCTTAA 660
GTGTGCTGGA ATTCTGCATT GCTGTGTCCC TCTCTGCCTT TGGATGTAAA GTGCTCTGTT 720
GTACCCCTGG TGGGGTTGTG TTAATTCTGC CATCACATTC TCACATGGCA GAAACAGCAT 780
CTCCCACACC ACTTAATGAG GTTTGAGGCC ACCAAAAGAT CAACAGACAA ATGCTCCAGA 840
AATCTATGCT GACTGTGACA CAAβAβCCTC ACATGAGAAA TTACCAGTAT CCAACTTCGA 900
TACTGATAGA CTTGTTGATA TTATTATTAT ATGTAATCCA ATTATGAACT GTGTGTGTAT 960
AGAGAGATAA TAAATTCAAA ATTATβTTCT CATTTTTTTC CCTGGAACTC AATAACTCAT 1020
TTCACTGGCT CTTTATCGAG AGTACTAGAA GTTAAATTAA TAAATAATGC ATTTAATGAG 1080
GCAACAGCAC TTGAAAGTTT TTCATTCATC ATAAGAACTT TATATAAAGG CATTACATTG 1140 βCAAATAAGG TTTGGAAGCA GAAGAGCAAA AAAAAGATAT TGTTAAAATG AGGCCTCCAT 1200
GCAAAACACA TACTTCCCTC CCATTTATTT AACTTTTTTT TTCTCCTACC TATGGGGACC 1260
AAAGTGCTTT TTCCTTCAGG AAGTGGAGAT GCATGGCCAT CTCCCCCTCC CTTTTTCCTT 1320
CTCCTβCTTT TCTTTCCCCA TAGAAAGTAC CTTGAAGTAG CACAGTCCGT CCTTGCATGT 1380
GCACGAGCTA TCATTTGAGT AAAAGTATAC ATGGAGTAAA AATCATATTA AGCATCAGAT 1440
TCAACTTATA TTTTCTATTT CATCTTCTTC CTTTCCCTTC TCCCACCTTC TACTGGGCAT 1500
AATTATATCT TAATCATATA TGGAAATGTG CAACATATGβ TATTTGTTAA ATACGTTTGT 1560
TTTTATTGCA GAGCAAAAAT AAATCAAATT AβAAGCAATA AAAAAAAAAA AAAAAAAAA 1619 Seq ID NO: C148 DNA Sequence
Nucleic Acid Accession ft: NM_002091.1
Coding sequence: 56..502
11 21 31
AGTCTCTGCT CTTCCCAGCC TCTCCGGCGC GCTCCAAGGG CTTCCCGTCG GGACCATGCG 60
CGGCAGTGAG CTCCCGCTGG TCCTGCTGGC GCTGGTCCTC TGCCTAGCGC CCCGGGGGCG 120
AGCGGTCCCG CTGCCTGCGβ GCGGAGGβAC CGTGCTGACC AAGATGTACC CGCGCGGCAA 180
CCACTGGGCG GTGGGGCACT TAAT6GGGAA AAAGAGCACA GGGGAGTCTT CTTCTGTTTC 240
TGAGAGAGGG AGCCTGAAGC AGCAβCTGAG AGAGTACATC AGGTGGGAAG AAGCTGCAAG 300
GAATTTGCTβ GGTCTCATAG AAGCAAAGGA GAACAGAAAC CACCAGCCAC CTCAACCCAA 360
GGCCTTGGGC AATCAGCAGC CTTCGTGGGA TTCAGAGGAT AGCAGCAACT TCAAAGATGT 420
AGGTTCAAAA GGCAAAGTTG GTAGACTCTC TGCTCCAGGT TCTCAACGTG AAGGAAGGAA 480
CCCCCAGCTG AACCAGCAAT GATAATGATG GCCTCTCTCA AAAGAGAAAA ACAAAACCCC 540
TAAGAGACTG AGTTCTGCAA GCATCAGTTC TACGGATCAT CAACAAGATT TCCTTGTGGA 600
AAATATTTGA CTATTCTGTA TCTTTCATCC TTGACTAAAT TCGTGATTTT CAAGCAGCAT 660
CTTCTGGTTT AAACTTGTTT GCTGTGAACA ATTGTCGAAA AGAGTCTTCC AATTAATβCT 720
TTTTTATATC TAGGCTACCT GTTGβTTAGA TTCAAGβCCC CGAGCTGTTA CCATTCACAA 780
TAAAAGCTTA AACACAT 797
Seq ID NO: C149 DNA Sequence Nucleic Acid Accession ff: NM_012261. Coding sequence: 203..1045
1 11 21 31 41 51
1 1 | 1 | 1 | 1 1 1 | 1 GATTTGCTCT GCCAGCAGCT GTCGGTGCCG CGCTCGACAC CGAGTCCTAG CTAGGCGCTC 60
ACAGAATACG CGCTGCCTCC CTCCCCCTTC TCTGTCCCCC GCCTCTCGCT CACCCCGGCC 120
CACTCCAGCG GCGACTTTGA GGGATTCCCT CTCTGGCGGC CTCTGCAGCA βCACAGCCGG 180
CCTCATTCGG GGCACTGCβA GTATGGATCT CCAAGGAAGA GGGGTCCCCA GCATCGACAG 240
ACTTCGAGTT CTCCTGATGT TGTTCCATAC AATGGCTCAA ATCATGGCAG AACAAGAAGT 300
GGAAAATCTC TCAGGCCTTT CCACTAACCC TGAAAAAGAT ATATTTGTGG TGCeeβAAAA 360
TGGGACGACG TGTCTCATGG CAGAGTTTGC AGCCAAATTT ATTGTACCTT ATβATβTGTG 420
GGCCAGCAAC TACGTAGATC TGATCACACA ACAGGCCGAT ATCGCATTGA CCCGGGGAGC 480
TGAGGTGAAG GGCCGCTGTβ GCCACAGCCA GTCGGAGCTG CAAGTGTTCT GGGTGGATCG 540
CGCATATGCA CTCAAAATGC TCTTTGTAAA GGAAAGCCAC AACATGTCCA AββGACCTGA 600
GGCGACTTGG AGGCTβAGCA AAGTGCA6TT TGTCTACGAC TCCTCGGAGA AAACCCACTT 660
CAAAGACGCA GTCAGTGCTG ββAAβCACAC AGCCAACTCG CACCACCTCT CTGCCTTGβT 720
CACCCCCGCT GGGAAβTCCT ATGAGTGTCA AGCTCAACAA ACCATTTCAC TβGCCTCTAG 780
TGATCCGCAG AAGACβGTCA CCATGATCCT GTCTGCGGTC CACATCCAAC CTTTTGACAT 840
TATCTCAGAT TTTGTCTTCA CTβAAGAGCA TAAATGCCCA GTGGATGAGC ββGAGCAACT 900
GGAAGAAACC TTGCCCCTGA TTTTGGGGCT CATCTTGGGC CTCGTCATCA TGβTAACACT 960
CGCGATTTAC CACGTCCACC ACAAAATGAC TGCCAACCAG GTβCAβATCC CTCGGGACAG 1020
ATCCCAGTAT AAGCACATGG GCTAGAGGCC GTTAGGCAGG CACCCCCTAT TCCTGCTCCC 1080
CCAACTGGAT CAGGTAGAAC AACAAAAGCA CTTTTCCATC TTGTACACGA GATACACCAA 1140
CATAGCTACA ATCAAACAGG CCTGGGTATC TGAGGCTTGC TTGGCTTGTG TCCATGCTTA 1200
AACCCACGGA AGGGGGAGAC TCTTTCGGAT TTGTAGGGTG AAATGGCAAT TATTCTCTCC 1260
ATGCTGGGGA GGAGGGGAGG AGGGTCTCAG ACAGCTTTCG TGCTCATGGT GGCTTGGCTT 1320
TGACTCTCCA AAGAGCAATA AATGCCACTT GGAGCTGTAT CTGGCCCCAA AGTTTAGGGA 1380
TTGAAAACAT GCTTCTTTGA GGAGGAAACC CCTTTAGGTT CAGAAβAATA TGGβGTGCTT 1440
TGCTCCCTTG GACACAGCTG βCTTATCCTA TACAGTTβTC AATβCACACA GAATACAACC 1500
TCATGCTCCC TGCAGCAAGA CCCCTGAAAG TGATTCATGC TTCTGGCTβG CATTCTGCAT 1560
GTTTAGTGAT TGTCTTGGGA ATGTTTCACT GCTACCCGCA TCCAGCGACT GCAGCACCAG 1620
AAAACGACTA ATGTAACTAT GCAGAGTTGT TTGGACTTCT TCCTGTGCCA GGTCCAAGTC 1680
GGGGGACCTG AAGAATCAAT CTGTGTβAβT CTGTTTTTCA AAATGAAATA AAACACACTA 1740
TTCTCTGGC 1749
Seq ID NO: C150 DNA Sequence
Nucleic Acid Accession ff: NM_003226.1
Coding sequence: 2..226
1 11 21 31 41 51
1 1 1 I 1 1 1 I 1 1 1
GATβCTGGGG CTGGTCCTGG CCTTGCTGTC CTCCAGCTCT GCTGAGGAGT ACCTGGGCCT 60
GTCTGCAAAC CACTGTGCCG TGCCGGCCAA GGACAGGGTG GACTGCGGCT ACCCCCATGT 120
CACCCCCAAG GAGTGCAACA ACCGGGGCTG CTGCTTTGAC TCCAGGATCC CTGGAGTGCC 180
TTGGTGTTTC AAGCCCCTGA CTAGGAAGAC AGAATGCACC TTCTGAGGCA CCTCCAGCTG 240
CCCCTGGGAT GCAGGCTGAG CACCCTTGCC CGGCTGTGAT TGCTGCCAGβ CACTGTTCAT 300
CTCAGTTTTT CTGTCCCTTT GCTCCCGGCA AGCTTTCTGC TGAAAGTTCA TATCTGGAGC 360
CTβATβTCTT AACGAATAAA GGTCCCATGC TCCACCCG 398 Seq ID NO: C151 DNA Sequence
Nucleic Acid Accession ff: NM_002993.1 Coding sequence: 64..408 1 11 21 31 41 51 i i I i i i
GGCACGAGCC AGTCTCCGCG CCTCCACCCA GCTCAGGAAC CCGCGAACCC TCTCTTGACC 60 ACTATGAGCC TCCCGTCCAG CCGCGCGβCC CGTGTCCCGG GTCCTTCGGG CTCCTTGTGC 120 GCGCTGCTCG CGCTGCTGCT CCTGCTGACG CCGCCGGGGC CCCTCGCCAG CGCTGGTGCT 180 GTCTCTGCTG TGCTGACAGA GCTGCGTTβC ACTTβTTTAC GCGTTACGCT GAβAGTAAAC 240 CCCAAAACGA TTGGTAAACT GCAGGTGTTC CCCGCAGGCC CGCAGTGCTC CAAGGTGGAA 300
GTGGTAGCCT CCCTGAAGAA CGGGAAGCAA GTTTGTCTGG ACCCGGAAGC CCCTTTTCTA 360
AAGAAAGTCA TCCAGAAAAT TTTGGACAGT GGAAACAAGA AAAACTGAGT AACAAAAAAG 420
ACCATGCATC ATAAAATTGC CCAGTCTTCA GCGGAGCAGT TTTCTGGAGA TCCGTGGACC 480
CAGTAAGAAT AAGAAGGAAG GGTTGGTTTT TTTCCATTTT CTACATGGAT TCCCTACTTT 540
GAAGAGTGTG GGGGAAAGCC TACGCTTCTC CCTGAAGTTT ACAGCTCAβC TAATGAAGTA 600
CTAATATAGT ATTTCCACTA TTTACTGTTA TTTTACCTGA TAAGTTATTβ AACCCTTTGG 660
CAATTGACCA TATTGTβAGC AAAGAATCAC TGGTTATTAG TCTTTCAATG AATATTGAAT 720
TGAAGATAAC TATTGTATTT CTATCATACA TTCCTTAAAG TCTTACCGAA AAGGCTGTGG 780
ATTTCGTATG GAAATAATGT TTTATTAGTG TGCTGTTGAG GGAGGTATCC TGTTGTTCTT 840
ACTCACTCTT CTCATAAAAT AGGAAATATT TTAGTTCTGT TTTCTTGGGG AATATGTTAC 900
TCTTTACCCT AGGATGCTAT TTAAGTTGTA CTGTATTAGA ACACTGGGTG TGTCATACCG 960
TTATCTGTGC AGAATATATT TCCTTATTCA GAATTTCTAA AAATTTAAGT TCTGTAAGGG 1020
CTAATATATT CTCTTCCTAT GGTTTTAGAT GTTTGATGTC TTCTTAGTAT GGCATAATGT 1080
CATGATTTAC TCATTAAACT TTGATTTTGT ATGCTATTTT TTCACTATAG GATGACTATA 1140
ATTCTGGTCA CTAAATATAC ACTTTAGATA GATGAAGAAG CCCAAAAACA GATAAATTCC 1200
TGATTGCTAA TTTACATAGA AATGTATTCT CTTGGTTTTT TAAATAAAAG CAAAATTAAC 1260
AATGATCTβT GCTCTGCAAA GTTTTGAAAA TATATTTGAA CAATTTGAAT ATAAATTCAT 1320
CATTTAβTCC TCAAAATATA TACAGCATTG CTAAGATTTT CAGATATCTA TTGTGGATCT 1380
TTTAAAGGTT TTGACCATTT TGTTATGAGG AATTATACAT GTATCACATT CACTATATTA 1440
AAATTGCACT TTTATTTTTT CCTGTGTGTC ATGTTGGTTT TTGGTACTTG TATTGTCATT 1500
TGGAGAAACA ATAAAAGATT TCTAAACCAA AAAAAAAAAA AAAAAAA 1547
Seq ID NO: C152 DNA Sequence
Nucleic Acid Accession #: NM_005242.2
Coding sequence: 148..1341
1 11 21 31 41 51 1 1 | 1 | 1 | 1 | 1 | 1
CGGCCC6CCC TGGGGAGGCβ CGCAGCAGAG GCTCCGATTC GGGGCAGGTβ AGAGGCTGAC 60
TTTCTCTCββ TGCGTCCAGT GGAGCTCTGA GTTTCGAATC GGTGGCβGCG GATTCCCCGC 120
GCGCCCGGCG TCGGGGCTTC CAGGAGGATG CGGAGCCCCA GCGCGGCGTG GCTGCTGGGG 180
GCCGCCATCC TGCTAGCAGC CTCTCTCTCC TGCAGTGGCA CCATCCAAGG AACCAATAGA 240
TCCTCTAAAβ CAAβAAβCCT TATTGGTAAG GTTGATGGCA CATCCCACGT CACTGGAAAA 300
GGAGTTACAG TTGAAACAGT CTTTTCTGTG GATGAGTTTT CTGCATCTGT CCTCACTGGA 360
AAACTGACCA CGGTCTTCCT TCCAATTGTC TACACAATTG TGTTTGTGGT GGGTTTGCCA 420
AGTAACGβCA TGGCCCTGTG GGTCTTTCTT TTCCGAACTA AGAAGAAGCA CCCTGCTGTG 480
ATTTACATGG CCAATCTGβC CTTGGCTGAC CTCCTCTCTG TCATCTGGTT CCCCTTGAAG 540
ATTGCCTATC ACATACATβC CAACAACTGG ATTTATGGGG AAGCTCTTTG TAATGTGCTT 600
ATTGGCTTTT TCTATβGCAA CATGTACTβT TCCATTCTCT TCATGACCTG CCTCAGTGTG 660
CAGAGGTATT GGGTCATCGT GAACCCCATG GGGCACTCCA GGAAGAAGGC AAACATTGCC 720
ATTGGCATCT CCCTGGCAAT ATGβCTβCTG ATTCTGCTGG TCACCATCCC TTTGTATGTC 780
GTGAAGCAGA CCATCTTCAT TCCTGCCCTG AACATCACGA CCTGTCATGA TGTTTTGCCT 840
GAGCAGCTCT TGGTGGGAGA CATGTTCAAT TACTTCCTCT CTCTGGCCAT TGGGGTCTTT 900
CTGTTCCCAG CCTTCCTCAC AGCCTCTGCC TATGTGCTGA TGATCAGAAT GCTGCGATCT 960
TCTGCCATGG ATGAAAACTC AGAβAAGAAA AGGAAGAGGG CCATCAAACT CATTGTCACT 1020
GTCCTGGCCA TGTACCTGAT CTGCTTCACT CCTAGTAACC TTCTGCTTGT GGTGCATTAT 1080
TTTCTGATTA AGAGCCAGβG CCAGAGCCAT GTCTATGCCC TGTACATTGT AGCCCTCTGC 1140
CTCTCTACCC TTAACAGCTG CATCGACCCC TTTGTCTATT ACTTTGTTTC ACATGATTTC 1200
AGGGATCATG CAAAGAACGC TCTCCTTTGC CGAAGTGTCC GCACTGTAAA GCAGATGCAA 1260
GTATCCCTCA CCTCAAAGAA ACACTCCAGG AAATCCAβCT CTTACTCTTC AAGTTCAACC 1320
ACTGTTAAGA CCTCCTATTG AGTTTTCCAG GTCCTCAGAT GGGAATTGCA CAGTAGGATG 1380
TGGAACCTGT TTAATGTTAT GAGGACGTGT CTGTTATTTC CTAATCAAAA AGGTCTCACC 1440
ACATACCACC G 1451
Seq ID NO: C153 DNA Sequence
Nucleic Acid Accession ft: NM_003469.2
Coding sequence: 92..1945
11 21 31 41 51
GAAACGGCCC G IAGAAGCTCC C ICCGGAGAAC G IGGGAGGAAT A ITGCTGTGGA GGTCCTCTGC 60 CATATAAACA AAAAGAGGAA ATCTTTCAAA CATGGCTGAA GCAAAGACCC ACTGGCTTGG 120 AGCAGCCCTG TCTCTTATCC CTTTAATTTT CCTCATCTCT GGGGCTGAAG CAGCTTCATT 180 TCAGAGAAAC CAGCTGCTTC AGAAAGAACC AGACCTCAGG TTGGAAAATG TCCAAAAGTT 240 TCCCAGTCCT GAAATGATCA GGGCTTTGGA GTACATAGAA AACCTCCGAC AACAAGCTCA 300 TAAGGAAGAA AGCAGCCCAG ATTATAATCC CTACCAAGGT GTCTCTGTCC CCCTTCAGCA 360 AAAAGAAAAT GGCGATGAAA GCCACTTGCC CGAGAGGGAT TCACTGAGTG AAGAAGACTG 420 GATGAGAATA ATACTCGAAG CTTTGAGACA GGCT6AAAAT GAGCCTCAGT CTGCACCAAA 480 AGAAAATAAG CCCTATGCCT TGAATTCAGA AAAGAACTTT CCAATGGACA TGAGTGATGA 540 TTATβAβACA CAGCAβTGGC CAGAAAGAAA GCTTAAGCAC ATGCAATTCC CTCCTATGTA 600 TGAAGAGAAT TCCAGGGATA ACCCCTTTAA ACGCACAAAT GAAATAGTGG AGGAACAATA 660 TACTCCTCAA AGCCTTGCTA CATTGGAATC TGTCTTCCAA GAGCTGGGGA AACTGACAGG 720 AGCAAACAAC CAGAAACGTG AGAGGATGGA TGAGGAGCAA AAACTTTATA CGGATGATGA 780 AGATGATATC TACAAGGCTA ATAACATTGC CTATGAAGAT GTGβTCGGGG GAGAAGACTG 840 GAACCCAGTA GAβGAGAAAA TAGAGAGTCA AACCCAGGAA GAGGTGAGAG ACAGCAAAGA 900 GAATATAGGA AAAAATGAAC AAATCAACGA TGAGATGAAA CGCTCAGGGC AGCTTGGCAT 960 CCAGβAAGAA GATCTTCGGA AAGAGAGTAA AGACCAACTC TCAGATGATG TCTCCAAAGT 1020 AATTGCCTAT TTGAAAAGGT TAGTAAATGC TGCAGGAAGT GGGAGGTTAC AGAATGGGCA 1080 AAATGGGGAA AGGGCCACCA GGCTTTTTGA GAAACCTCTT GATTCTCAGT CTATTTATCA 1140 GCTGATTGAA ATCTCAAGGA ATTTACAGAT ACCCCCAGAA GACTTAATTG AGATGCTCAA 1200 AACTGGGGAG AAGCCGAATG GATCAGTGβA ACCGGAGCGG GAGCTTGACC TTCCTGTTGA 1260 CCTAGATGAC ATCTCAGAβG CTCACTTAGA CCATCCAGAC CTGTTCCAAA ATAGGATGCT 1320 CTCCAAGAGT βGCTACCCTA AAACACCTGβ TCGTGCTβGG ACTGAGGCCC TACCAGACGG 1380
GCTCAGTGTT GAGGATATTT TAAATCTTTT AGGGATGGAG AGTGCAGCAA ATCAGAAAAC 1440
GTCGTATTTT CCCAATCCAT ATAACCAGGA GAAAGTTCTG CCAAGGCTCC CTTATββTGC 1500
TGGAAGATCT AGATCGAACC AGCTTCCCAA AGCTGCCTGG ATTCCACATG TTβAAAACAβ 1560
ACAGATGGCA TATGAAAACC TGAACGACAA GGATCAAGAA TTAGGTβAGT ACTTGGCCAG 1620
GATGCTAGTT AAATACCCTG AGATCATTAA TTCAAACCAA GTGAAGCGAβ TTCCTGGTCA 1680
AGGCTCATCT GAAGATGACC TβCAGGAAGA GGAACAAATT GAGCAG6CCA TCAAAGAβCA 1740
TTTGAATCAA GGCAGCTCTC AGGAGACTGA CAAGCTGGCC CCGGTGAGCA AAAGGTTCCC 1800
TGTGGGGCCC CCGAAGAATG ATGATACCCC AAATAGGCAG TACTGGGATG AAGATCTGTT 1860
AATGAAAGTG CTGGAATACC TCAATCAAGA AAAGGCAβAA AAGGGAAGGG AGCATATTGC 1920
TAAGAGAGCA ATGGAAAATA TGTAAGCTGC TTTCATTAAT TACCCTACTT TCATTCCTCC 1980
CACCCCAAGC AAATCCCAAC ATTTCTCTTC AGTGTGTTGA CTTCTATCCT GTTAACACTG 2040
TAATATCTTT AAATGATGTA CAGGCAGATG AAACCAGGTC ACTGGGGAGT CTGCTTCATT 2100
TCCTCTGAGC TGTTATCTTG TGTATGGATA TGTGTAAATG TTATGACTCC TTGATAAAAA 2160
ATTTATTATG TCCATTATTC AAGAAAGATA TCTATGACTG TGTTTAATAG TATATCTAAT 2220
GβCTGTGGCA TTGTTGATGC TCACATATGA TAAAAAAGTG TCCTATAATT CTATTGAAAG 2280
TTTTTAATAT TTATTGAATT ATTTTGTTAC TGTCTGTAGC GTTTTGTGGA GTACTGGACC 2340
AAAAAAATAA AGCATTATAA ATATA 2365
Seq ID NO: C154 DNA Sequence Nucleic Acid Accession ft: NM_030955 Coding sequence: 327..5108
1 11 21 31 41 51
I I I I I I
GAATTCCGGG AGCGGGCGGG CTGCGAGGCC GCGGGGCATG CGG6AGGCGG AGGGGTGGGA 60
CCGGGTGGCT GCGCCCATTC CACACCCGCC GAAAGCGGAC ACTGTCAGCT GAATCACTCC 120
CCTTTTAGGA GGAGGGAGGG GGAAAAGGTG TCTAGCTAAT TTCTGCTTAA AAAAGCACAG 180
GAGATCGCGG GTCAβCTTTβ CAGTCGCTGC CTTCTCGCGC CTGACCATGC ACCCCTGCAT 240
CTTCCTGCTβ GGCACAGGCG AGCGCTTTAT TTCTGGAGCT GAGGβCTAAA ACTTTTTTCA 300
CTTTTCTTCT CCTCAACATC TGAATCATGC CATGTGCCCA GAβGAGCTGG CTTGCAAACC 360
TTTCCGTGGT GGCTCAβCTC CTTAACTTTG GGGCGCTTTG CTATGGβAβA CAβCCTCAGC 420
CAGGCCCGGT TCGCTTCCCG GACAGGAGGC AAGAGCATTT TATCAAGGGC CTGCCAGAAT 480
ACCACGTGGT GGGTCCAGTC CGAGTAGATG CCAGTGGβCA TTTTTTGTCA TATGGCTTGC 540
ACTATCCCAT CACGAGCAGC AββAGGAAGA GAGATTTGGA TGGCTCAGAG GACTGGGTGT 600
ACTACAGAAT TTCTCACGAG GAGAAGGACC TGTTTTTTAA CTTGACGGTC AATCAAGGAT 660
TTCTTTCCAA TAGCTACATC ATGGAGAAGA GATATGGGAA CCTCTCCCAT GTTAAGATGA 720
TGGCTTCCTC TGCCCCCCTC TGCCATCTCA GTGGCACGGT TCTACAGCAG GGCACCAGAG 780
TTGGGACGGC AGCCCTCAGT GCCTGCCATG GACTGACTGG ATTTTTCCAA CTACCACATG 840
GAGACTTTTT CATTGAACCC βTGAAGAAGC ATCCACTGGT TGAβGGAGGG TACCACCCGC 900
ACATCGTTTA CAGGAGGCAG AAA6TTCCAG AAACCAAGβA GCCAACCTGT GGATTAAAGG 960
ACAGTGTTAA CATCTCCCAG AAGCAAGAGC TATGGCGGGA GAAGTGGGAβ AGGCACAACT 1020
TGCCAAGCAG AAGCCTCTCT C6GCGTTCCA TCAGCAAGGA GAGATGGGTG GAGACACTGG 1080
TGGTGGCCGA CACAAAGATG ATTGAATACC ATGGGAGTGA GAATGTGGAG TCCTACATCC 1140
TCACCATCAT GAACATGGTC ACTGGGTTβT TCCATAACCC AAGCATTGGC AATGCAATTC 1200
ACATTGTTGT GGTTCGGCTC ATTCTACTCG AAGAAGAAGA GCAAGGACTG AAAATAGTTC 1260
ACCATCCAGA AAAGACACTG TCTAGCTTCT GCAAGTGGCA GAAGAGTATC AATCCCAAGA 1320
GTGACCTCAA TCCTGTTCAT CACGACGTGG CTGTCCTTCT CACCAGAAAG GACATCTGTG 1380
CTGGTTTCAA TCGCCCCTGC GAGACCCTGG GCCTGTCTCA CCTTTCAGGA ATGTGTCAGC 1440
CTCACCGCAG TTGTAACATC AATCAAGATT CGGGACTCCC TCTGGCTTTC ACAATTGCCC 1500
ATGAβCTAGG ACACAGCTTC GGCATCCAGC ATGATGGGAA AGAAAATGAC TGTGAGCCTG 1560
TGGGCAβACA TCCGTACATC ATGTCCCGCC AGCTCCAGTA CGATCCCACT CCCCTGACAT 1620
GGTCCAAGTG CAGCGAGGAG TACATCACCC GCTTCTTGGA CCGAGGCTGG GGGTTCTGTC 1680
TTGATGACAT ACCTAAAAAG AAAGGCTTGA AGTCCAAGGT CATTGCCCCC βGAGTGATCT 1740
ATGATGTTCA CCACCAGTGC CAGCTACAAT ATGGACCCAA TGCTACCTTC TGCCAGGAAG 1800
TAGAAAACGT CTGCCAGACA CTGTGGTGCT CCGTGAAGGG CTTTTGTCGC TCTAAGCTGG 1860
ACGCTGCTGC AGATGGAACT CAATGTGGTβ AGAAGAAGTG GTGTATGGCA GGCAAGTGCA 1920
TCACAGTGGG GAAGAAACCA GAGAGCATTC CTGGAGGCTG GGGCCGCTGG TCACCCTGCT 1980
CCCACTGTTC CAGβACCTGT GGGGCTGGAG TCCAGAGCGC AGAGAGGCTC TGCAACAACC 2040
CCGAGCCAAA GTTTGGAGGG AAATATTGCA CTGGAGAAAβ AAAACGCTAT CGCTTGTGCA 2100
ACGTCCACCC CTGTCGCTCA GAGβCACCAA CATTTCGGCA GATGCAGTGC AGTGAATTTG 2160
ACACTGTTCC CTACAAGAAT GAACTCTACC ACTGGTTTCC CATTTTTAAC CCAGCACATC 2220
CTTGTGAβCT CTACTGCCGA CCCATAGATG GCCAGTTTTC TGAGAAAATG CTGGATGCTG 2280
TCATTGATGG TACCCCTTGC TTTGAAGGCG GCAACAGCAG AAATGTCTGT ATTAATGGCA 2340
TATGTAAGAT GGTTGGCTGT GACTATGAGA TCGATTCCAA TGCCACCGAG GATCGCTGCG 2400
GTGTGTGCCT GGGAGATΘ3C TCTTCCTGCC AGACTGTGAG AAAGATGTTT AAGCAGAAGG 2460
AAGGATCTGG TTATGTTGAC ATTGGGCTCA TTCCAAAAGG AGCAAGGGAC ATAAGAGTGA 2520
TGGAAATTGA GGGAGCTGGA AACTTCCTGG CCATCAGGAG TGAAGATCCT GAAAAATATT 2580
ACCTGAATGβ AGGGTTTATT ATCCAGTGGA ACGGGAACTA TAAGCTGGCA GGGACTGTCT 2640
TTCAGTATGA CAGβAAAGGA GACCTGGAAA AGCTGATGGC CACAGGTCCC ACCAATGAGT 2700
CTGTGTGGAT CCAGCTTCTA TTCCAGGTGA CTAACCCTGG CATCAAGTAT GAGTACACAA 2760
TCCAGAAAGA TGGCCTTGAC AATGATGTTG AGCAGATGTA CTTCTGGCAG TACG6CCACT 2820
GGACA6AGTG CAβTGTGACC TGCGGGACAG GTATCCGCCG CCAAACTGCC CATTGCATAA 2880
ACAAGGGCCβ CGGGATGGTG AAAGCTACAT TCTGTGACCC AGAAACACAG CCCAATGGGA 2940
GACAGAAGAA GTGCCATGAA AAGGCTTGTC CACCCAGGTG GT6GGCAGGG GAGTβGGAAG 3000
CATGCTCGGC GACATGCGGG CCCCACGGGG AGAAGAAGCG AACCGTGCTG TGCATCCAGA 3060
CCATGCTCTC TGACGAGCAG GCTCTCCCGC CCACAGACTG CCAGCACCTG CTGAAGCCCA 3120
AGACCCTCCT TTCCTβCAAC AGAGACATCC TGTGCCCCTC GGACTGGACA GTGGGCAACT 3180
GGAGTGAGTG TTCTGTTTCC TGTGβTGGTG GAGTGCGGAT TCGCAGTGTC ACATGTGCCA 3240
AGAACCATGA TGAACCTTGC GATGTGACAA GGAAACCCAA CAGCCGAGCT CTGTβTβGCC 3300
TCCAGCAATG CCCTTCTAGC CGGAGAGTTC TGAAACCAAA CAAAGGCACT ATTTCCAATG 3360
GAAAAAACCC ACCAACACTA AAGCCCGTCC CTCCACCTAC ATCCAGGCCC AGAATGCTGA 3420
CCACACCCAC AGGGCCTGAG TCTATGAGCA CAAGCACTCC AGCAATCAGC AGCCCTAGTC 3480
CTACCACAGC CTCCAAAGAA GGAGACCTGG GTGGGAAACA GTGGCAAGAT AGCTCAACCC 3540 AACCTGAGCT GAGCTCTCGC TATCTCATTT CCACTGGAAG CACTTCCCAG CCCATCCTCA 3600
CTTCCCAATC CTTGAGCATT CAGCCAAGTG AGGAAAATGT TTCCAGTTCA GATACTGGTC 3660
CTACCTCGGA GGGAGGCCTT GTAGCTACAA CAACAAGTGG TTCTGGCTTG TCATCTTCCC 3720
GCAACCCTAT CACTTGGCCT GTGACTCCAT TTTACAATAC CTTGACCAAA GGTCCAGAAA 3780
TGGAβATTCA CAGTGGCTCA GGGGAAGAAA GAGAACAGCC TGAGGACAAA GATGAAAGCA 3840
ATCCTGTAAT ATGGACGAAG ATCAGAGTAC CTGGAAATGA CGCTCCA6TG GAAAGTACAG 3900
AAATβCCACT TGCACCTCCA CTAACACCAG ATCTCAGCAβ GβAβTCCTβG TGGCCACCCT 3960
TCAGCACAGT AATGGAAGGA CTGCTCCCCA βCCAAAGGCC CACTACTTCC GAAACTGββA 4020
CACCCAGAβT TGAGGGGATG GTTACTGAAA AGCCAGCCAA CACTCTGCTC CCTCTGGGAG 4080
GAGACCACCA GCCAGAACCC TCAGGAAAGA CGGCAAACCG TAACCACCTG AAACTTCCAA 4140
ACAACATGAA CCAAACAAAA AGTTCTGAAC CAGTCCTGAC TGAGGAGGAT GCAACAAGTC 4200
TGATTACTGA GGGCTTTTTG CTAAATGCCT CCAATTACAA GCAGCTCACA AACGGCCACG 4260
GCTCTGCACA CTGGATCGTC GGAAACTGGA GCGAβTGCTC CACCACATGT GGCCTGGGGG 4320
CCTACTGGAA AAGGGTGGAG TGCACCACCC AGATGGATTC TGACTGTGCG GCCATCCAGA 4380
GACCTGACCC TGCAAAAAGA TGCCACCTCC GTCCCTβTGC TGGCTGGAAA GTGGβAAACT 4440
GGAGCAAGTβ CTCCAGAAAC TGCAβTGGGG GCTTCAAGAT ACGCGAGATT CAGT6CGTGG 4500
ACAGCCGGβA CCACCGGAAC CTGAGGCCAT TTCACTGCCA GTTCCTGGCC GGCATTCCTC 4560
CCCCATTCAβ CATGAGCTGT AACCCGGAGC CCTGTGAGGC GTGGCAGGTG GAGCCTTG6A 4620
GCCAGTGCTC CAGGTCCTGT GGAGGTGGAG TTCAGGAGAG AGGAGTGTTC TβTCCACβAβ 4680
GCCTCTGTGA TTGGACAAAA AGACCCACAT CCACCATGTC TTGCAATGAG CACCTGTGCT 4740
GTCACTGββC CACTGGGAAC TGGGACCTGT GTTCCACTTC CTGTGGAGGT GGCTTTCAGA 4800
AGAGGATTGT CCAATGTGTG CCCTCAGAGG βCAATAAAAC TGAAGACCAA GACCAATGTC 4860
TATGTGATCA CAAACCCAGA CCTCCAGAAT TCAAAAAATG CAACCAGCAG βCCTGCAAGA 4920
AAAGTGCCGA TTTACTTTGC ACTAAGGACA AACTGTCAGC CAGTTTCTGC CAβACACTGA 4980
AAGCCATGAA GAAATβTTCT GTGCCCACCG TGAGGGCTGA GTGCTGCTTC TCGTGTCCCC 5040
AGACACACAT CACACACACC CAAAGGCAAA GAAGGCAACG GTTβCTCCAA AAGTCAAAAG 5100
AACTCTAAGC CCAAA 5115
Seq ID NO: C155 DNA Sequence Nucleic Acid Accession # : NM_001062 .1
Coding sequence : 76. .1380
11 21 31 41 51
I I I I
GCTCTCATTA C 1CTTCTGCCC ATCACTTAAT AAATAGCCAG CCAATTCATC AACATTCTGG 60 TACACTGTTG GAGAGATβAβ ACAGTCACAC CAGCTGCCCC TAGTGGGGCT CTTACTGTTT 120 TCTTTTATTC CAAGCCAACT ATGCGAGATT TGTGAGGTAA GTGAAGAAAA CTACATCCGC 180 CTAAAACCTC TGTTGAATAC AATGATCCAG TCAAACTATA ACAGGGGAAC CAGCβCTGTC 240 AATGTTGTGT TGTCCCTCAA ACTTGTTGGA ATCCAGATCC AAACCCTGAT GCAAAAGATG 300 ATCCAACAAA TCAAATACAA TGTGAAAAGC AGATTGTCAG ATGTAAGCTC GGGAGAGCTT 360 GCCTTGATTA TACTGGCTTT GGGAGTATGT CGTAACGCTG AGGAAAACTT AATATATGAT 420 TACCACCTGA CTβACAAβCT AGAAAATAAA TTCCAAGCAG AAATTGAAAA TATGβAAβCA 480 CACAATGGCA CTCCCCTGAC TAACTACTAC CAGCTCAGCC TGGACGTTTT GGCCTTGTGT 540 CTGTTCAATG GGAACTACTC AACCGCCGAA GTTGTCAACC ACTTCACTCC TGAAAATAAA 600 AACTATTATT TTGGTAGCCA GTTCTCAGTA GATACTGβTβ CAATGGCTGT CCTGGCTCTG 660 ACCTGTGTGA AGAAGAGTCT AATAAATGGG CAGATCAAAG CAGATGAAGG CAGTTTAAAG 720 AACATCAGTA TTTATACAAA GTCACTGGTA GAAAAGATTC TGTCTGAGAA AAAAGAAAAT 780 GGTCTCATTG GAAACACATT TAβCACAGGA GAAGCCATGC AGGCCCTCTT TGTATCATCA 840 GACTATTATA ATGAAAATGA CTGGAATTGC CAACAAACTC TGAATACAGT GCTCACGGAA 900 ATTTCTCAAG GAGCATTCAG TAATCCAAAC GCTGCAGCCC AGGTCTTACC TGCCCTβATG 960 GGAAAGACCT TCTTGGATAT TAACAAAGAC TCTTCTTGCG TCTCTGCTTC AGGTAACTTC 1020 AACATCTCCG CTGATGAGCC TATAACTGTG ACACCTCCTG ACTCACAATC ATATATCTCC 1080 GTCAATTACT CTGTGAGAAT CAATGAAACA TATTTCACCA ATGTCACTGT GCTAAATGGT 1140 TCTGTCTTCC TCAGTGTGAT GGAGAAAGCC CAGAAAATGA ATβATACTAT ATTTGGTTTC 1200 ACAATGGAGG AGCGCTCATG GGGGCCCTAT ATCACCTGTA TTCAGGGCCT ATGTGCCAAC 1260 AATAATGACA GAACCTACTG GβAACTTCTβ AGTGGAGGCG AACCACTGAG CCAAGGAGCT 1320 GGTAGTTACG TTGTCCGCAA TGGAGAAAAC TTGGAβGTTC GCTGGAGCAA ATACTAATAA 1380 GCCCAAACTT TCCTCAGCTG CATAAAATCC ATTTβCAGTG GAGTTCCATG TTTATTGTCC 1440 TTATGCCTTC TTCTTCATTT ATCCCAGTAC GAGCAGGAGA GTTAATAACC TCCCCTTCTC 1500 TCTCTACATG TTCAATAAAA GTTGTTGAAA GATTAAC 1537
Seq ID NO: C156 DNA Sequence Nucleic Acid Accession ft: NM_004591 Coding sequence: 59..349
1 11 21 31 41 51 I 1 | 1 | 1 | 1 | 1 | 1 CACTCCCAAA GAACTGGGTA CTCAACACTG AGCAGATGTG TTCTTTGAGC TAAAAACCAT 60
GTGCTGTACC AAGAGTTTGC TCCTGGCTGC TTTGATGTCA GTGCTGCTAC TCCACCTCTβ 120
CGGCGAATCA GAAGCAGCAA GCAACTTTGA CTGCTGTCTT GGATACACAG ACCGTATTCT 180
TCATCCTAAA TTTATTGTGG GCTTCACACG GCAGCTGGCC AATGAAGGCT GTGACATCAA 240
TGCTATCATC TTTCACACAA AGAAAAAGTT GTCTβTGTGC GCAAATCCAA AACAGACTTG 300
GGTGAAATAT ATTGTGCGTC TCCTCAGTAA AAAAGTCAAG AACATGTAAA AACTGTGGCT 360
TTTCTGGAAT GGAATTGGAC ATAGCCCAAG AACAGAAAGA ACCTTGCTGG GGTTGGAGGT 420
TTCACTTGCA CATCATGGAG GGTTTAGTGC TTATCTAATT TGTGCCTCAC TGGACTTGTC 480
CAATTAATGA AGTTGATTCA TATTGCATCA TAGTTTGCTT TGTTTAAGCA TCACATTAAA 540
GTTAAACTGT ATTTTATGTT ATTTATAGCT βTAGGTTTTC TGTGTTTAGC TATTTAATAC 600
TAATTTTCCA TAAGCTATTT TGGTTTAGTG CAAAGTATAA AATTATATTT GGGGGGGAAT 660
AAGATTATAT GGACTTTCTT GCAAGCAACA AGCTATTTTT TAAAAAAACT ATTTAACATT 720
CTTTTGTTTA TATTGTTTTG TCTCCTAAAT TGTTGTAATT GCATTATAAA ATAAGAAAAA 780
CATTAATAAG ACAAATATT 799
Seq ID NO: C157 DNA Sequence
Nucleic Acid Accession ft: NM 013271.1 Coding sequence : 27. .809
1 11 21 31 41 51 1 | | 1 1
1 1 1 | 1 | 1 TCCGGAGCCA GGCTCGCTβG GGCAGCATGG CGGGGTCGCC GCTGCTCTGG GGGCCGCGGG 60
CCGGGGGCGT CGGCCTTTTG GTGCTGCTGC TGCTCGGCCT GTTTCGβCCG CCCCCCGCGC 120
TCTGCGCGCG GCCGGTAAAG GAACCCCGCG GCCTAAGCGC AGCGTCTCCG CCCTTGGCTG 180
AGACTGGCGC TCCTCGCCGC TTCCGβCGGT CAGTGCCCCG AGGTGAGGCG GCGGGGGCCβ 240
TGCAGβAβCT GGCCCβGGCG CTGGCGCATC TGCTGGA6GC CGAACGTCAG GAGCGGGCGC 300
GGGCCGAGGC GCAβGAGGCT GAGGATCAGC AGβCCCGCGT CCTGGCGCAG CTGCTβCGCβ 360
TCTGGGGCGC CCCCCGCAAC TCTGATCCGG CTCTGGGCCT GGACGACGAC CCCGACGCGC 420
CTCCACCCCA GCTCGCTCGC GCTCTGCTCC GCGCCCGCCT TGACCCTGCC βCCCTAGCAG 480
CCCAGCTTGT CCCCGCGCCC GTCCCCGCCG CGGCGCTCCG ACCCCGGCCC CCGGTCTACG 540
ACGACGGCCC CGCGGGCCCG GATGCTGAGG AGβCAGGCGA CGAGACACCC GACGTGGACC 600
CCGAGCTGTT GAGGTACTTG CTGGGACGGA TTCTTGCGGG AAGCGCGGAC TCCGAGGGGG 660
TββCAβCCCC GCGCCGCCTC CGCCGTβCCG CCGACCACGA TGTGGGCTCT GAGCTGCCCC 720
CTGAββGCGT GCTGGβGGCG CTGCTGCGTG TGAAACβCCT AGAGACCCCG βCGCCCCAGG 780
TGCCTGCACG CCGCCTCTTβ CCACCCTGAG CACTβcccβe ATCCCGTGCA CCCTGGGACC 840
CAGAAGTGCC CCCGCCATCC CGCCACCAGβ ACTTCTCCCC GCCAGCAC6T CCAGA6CAAC 900
TTACCCCGGC CAGCCAGCCC TCTCACCCGA GGATCCCTAC CCCCTGGCCC ACAATAACAT 960
GATCTGAβC 969
,Seq ID NO: C158 DNA Sequence Nucleic Acid Accession # : NM_002245.2 Coding sequence: 183. .1193
11 21 31 eeecAGGAAG ACGβCβCTGC CCGGAGGAGC GGβGCGGGCG GGCGCGCGβG GGAGCGGGCG 60
GCGGGCGGβA GCCAGGCCCG GGCGβGGGCG GGGβCGGCGG GGCCAGAAβA GGCββCβGGC 120
CGCGCTCCGG CCGGTCTGCβ GCGTTGGCCT TGGCTTTCGC TTTGGCGGCG GCGβTβGAGA 180
AGATGCTGCA GTCCCTGGCC GGCAGCTCGT GCGTGCGCCT βGTGβAβCGG CACCGCTCGG 240
CCTGGTβCTT CGβCTTCCTG GTβCTCGGCT ACTTGCTCTA CCTGGTCTTC GGCGCAGTββ 300
TCTTCTCCTC GGTGGAβCTβ CCCTAT6AGG ACCTGCTCCG CCACGAGCTβ CβCAAβCTβA 360
AGCGACβCTT CTTβGAGGAG CACGAGTGCC TGTCTβAGCA βCACCTGGAG CAGTTCCTGG 420
GCCGGGTGCT GGAGGCCAβC AACTACGGCG TGTCββTGCT CAGCAACeCC TCβGGCAACT 480
GGAACTGGGA CTTCACCTCC GCGCTCTTCT TCGCCAGCAC CβTβCTCTCC ACCACAGGTT 540
ATGGCCACAC CGTGCCCTTG TCAGATGGAG GTAAGGCCTT CTGCATCATC TACTCCGTCA 600
TTGGCATTCC CTTCACCCTC CTGTTCCTGA CGβCTβTGGT CCAGCGCATC ACCGTGCACβ 660
TCACCCGCAG GCCGGTCCTC TACTTCCACA TCCβCTGββG CTTCTCCAAG CAGβTGGTGG 720
CCATCGTCCA TGCCGTGCTC CTTGGβTTTβ TCACTGTCTC CTGCTTCTTC TTCATCCCGβ 780
CCGCTGTCTT CTCAGTCCTG GAGβATGACT GGAACTTCCT GGAATCCTTT TATTTTTGTT 840
TTATTTCCCT GAGCACCATT GGCCTGGGβG ATTATGTGCC TGβGGAAββC TACAATCAAA 900
AATTCAGAGA GCTCTATAAG ATTGβGATCA CβTβTTACCT GCTACTTGβC CTTATTGCCA 960
TGTTGGTAβT TCTGGAAACC TTCTGTGAAC TCCATGAGCT GAAAAAATTC AGAAAAATGT 1020
TCTATGTβAA GAAGGACAAG GACGAGGATC AGGTGCACAT CATAGAGCAT GACCAACTGT 1080
CCTTCTCCTC GATCACAGAC CAGGCAGCTG GCATGAAAGA GGACCAGAAG CAAAATGAGC 1140
CTTTTGTGGC CACCCAGTCA TCTGCCTGCG TGGATGGCCC TGCAAACCAT TGAGCGTAβG 1200
ATTTGTTGCA TTATGCTAβA βCACCAGGGT CAGGGTGCAA GGAAGAGGCT TAAGTATGTT 1260
CATTTTTATC AGAATGCAAA AGCGAAAATT ATβTCACTTT AAGAAATAβC TACTCTTT6C 1320
AATGTCTTAT TAAAAAACAA CAAAAAAAGA CACATGGAAC AAAβAAGCTG TGACCCCAGC 1380
AGGATGTCTA ATATGTGAGG AAATGAGATG TCCACCTAAA ATTCATATGT GACAAAATTA 1440
TCTCGACCTT ACATAGGAGG AGAATACTTG AAGCAβTATβ CTGCTβTββT TAGAAGCAGA 1500
TTTTATACTT TTAACTGGAA ACTTTGGGGT TTGCATTTAG ATCATTTAGC TGATGGCTAA 1560
ATAGCAAAAT TTATATTTAG AAGCAAAAAA AAAAAGCATA GAGATGTGTT TTATAAATAG 1620
GTTTATGTGT ACTGGTTTβC ATβTACCCAC CCAAAATGAT TATTTTTGGA GAATCTAAGT 1680
CAAACTCACT ATTTATAATG CATAGGTAAC CATTAACTAT GTACATATAA AGTATAAATA 1740
TGTTTATATT CTGTACATAT GGTTTAGGTC ACCAGATCCT AGTGTAGTTC TGAAACTAAG 1800
ACTATAGATA TTTTGTTTCT TTTGATTTCT CTTTATACTA AAGAATCCAG AGTTGCTACA 1860
ATAAAATAAG GGGAATAATA AACTTGAGAG TGAATAACCA T 1901
Seq ID NO: C159 DNA Sequence
Nucleic Acid Accession ft : NM_005472.1
Coding sequence: 93 . .404
11 21 31
AAAGGGACTC CTTGAAACTβ ATTGAβAGCC CAGTGGATTT GCCAGCAβTT TGAGCTTCTA 60
CCGAGTCTTC CCCCACCTCA ATCCCTGTTG CTATGGAGAC TACCAATGGA ACGGAGACCT 120
GβTATGAGAG CCTGCATGCC GTGCTGAAGG CTCTAAATGC CACTCTTCAC AGCAATTTGC 180
TCTGCCGGCC AGGGCCAGGG CTGGGGCCAG ACAACCAGAC TGAAGAGAGβ CGGGCCAGCC 240
TACCTGGCCG TGATGACAAC TCCTACATGT ACATTCTCTT TGTCATGTTT CTATTTGCTG 300
TAACTGTGGG CAGCCTCATC CTGGGATACA CCCGCTCCCG CAAAGTGGAC AAGCGTAGTG 360
ACCCCTATCA TGTGTATATC AAβAACCGTG TGTCTATGAT CTAACACGAG AGGGCTGGGA 420
CGGTGGAAGA CCAAGACACC TGGGGATTGC GTCTGGGGCC TCCAGAACTC TGCTGTGGAC 480
TGCATCAGGT CT 492
Seq ID NO: C160 DNA Sequence
Nucleic Acid Accession #: NM_005245.1
Coding sequence: 187..13959
1 11 21 31 41 51
I I I I I I
CTGGGCGGCC GGGCGCGGGG AGAGGGCGCG GGAGCGGCTC GTGCGβCAGG TACCATGCGG ACβCGCGAGC CCGβCGAGβC CCCGGCAGGC CCGTCCCTGC TCGGGGGCGC GCTGAGACGβ 120
CGGGTGAGCT CCACβAGAGC GCCGTCGCCA CTTCGGGCCA ACTTTGCGAT TCCCGACAGT 180
TAAGCAATGβ GGAGACATTT GGCTTTGCTC CTβCTTCTβC TCCTTCTCTT CCAACATTTT 240
GGAGACAGTG ATGGCAGCCA ACGACTTGAA CAGACTCCTC TGCAGTTTAC ACACCTCGAG 300
TACAACGTCA CCGTGCAGGA GAACTCTGCA GCTAAGACTT ATGTGGββCA TCCTβTCAAC 360
ATGGGTGTTT ACATTACACA TCCAGCGTGβ βAAβTAAGGT ACAAAATTGT TTCCGGAGAC 420
AGTGAAAACC TGTTCAAAGC TGAAGAGTAC ATTCTCGGAG ACTTTTGCTT TCTAAGAATA 480
AGβACCAAAG GAGGAAATAC AGCTATTCTT AATAGAGAAG TGAAGGATCA CTACACATTG 540
ATAGTβAAAG CACTTGAAAA AAATACTAAT GTGGAGGCβC GAACAAAGGT GAGGGTGCAG 600
GTGCTGβATA CAAATGACTT GAGACCGTTA TTCTCACCCA CCTCATACAG CGTTTCTTTA 660
CCTGAAAACA CAGCTATAAG GACCAGTATC GCAAGAGTCA GCβCCACGGA TGCAGACATA 720
GGAACCAACG GGGAATTTTA CTACAGTTTT AAAGATCGAA CAGATATGTT TGCTATTCAC 780
CCAACCAGTG GTGTGATAGT GTTAACTGGT AGACTTGATT ACCTAGAGAC CAACCTCTAT 840
GAGATGGAAA TCCTCGCTGC GGACCGTGGC ATGAAGTTGT ATGGGAGCAG TGGCATCAGC 900
AGCATGGCCA AGCTAACGGT βCACATCGAA CAGGCCAATG AATGTGCTCC GGTGATAACA 960
GCAGTGACAT TGTCACCATC AGAACTGGAC AGGGACCCAG CATATGCAAT TGT6ACAGTG 1020
GATGACTGCG ATCAGGGTGC CAATGGTGAC ATAGCATCTT TAAGCATCGT GGCAββTGAC 1080
CTTCTCCAGC AGTTTAGAAC AGTGAGGTCC TTTCCAGβGA GTAAGGAGTA TAAACTCAAA 1140
GCCATCGGTG ACATTGATTG GGACAGTCAT CCTTTCGβCT ACAATCTCAC ACTACAGGCT 1200
AAAGATAAAG GAACTCCGCC CCAGTTCTCT TCTGTTAAAG TCATTCACGT GACTTCTCCA 1260
CAGTTCAAAG CCGGGCCAGT CAAGTTTGAA AAGGATGTTT ACAGAGCAGA AATAAGTGAA 1320
TTTGCTCCTC CCAACACACC TGTGGTCATG GTAAAGGCCA TTCCTGCTTA TTCCCATTTG 1380
AGGTATGTTT TTAAAAGGAC ACCTGGAAAA GCTAAATTCA GTTTAAATTA CAACACTGGT 1440
CTCATTTCTA TTTTAGAACC AGTTAAAAGA CAGCAGGCAG CCCATTTTGA ACTTGAAGTA 1500
ACAAGAAGTG ACAGAAAAGC GTCCACCAAG βTCTTGGTGA AAGTCTTAGG TGCAAATAGC 1560
AATCCCCCTG AATTTACCCA GACAGCGTAC AAAGCTGCTT TTGATGAGAA CGTGCCCATT 1620
GGTACTACTA TCATGAGCCT GAGTGCCGTA GACCCTGATG AGββTGAGAA TGGGTACGTG 1680
ACATACAGTA TCGCAAATTT AAATCATGTG CCGTTTGCGA TTGACCATTT CACTGβTGCC 1740
GTGAGTACGT CAGAAAACCT GGACTACGAA CTGATGCCTC GGGTTTATAC TCTGAGGATT 1800
CGTGCATCAG ACTGβGGCTT GCCGTACCGC CGGGAAGTCG AAGTCCTTGC TACAATTACT 1860
CTCAATAACT TGAATGACAA CACACCTTTG TTTGAGAAAA TAAATTGTGA AβGGACAATT 1920
CCCAGAGATC TAGGCGTGGG AGAGCAAATA ACCACTGTTT CTGCTATTGA TGGAGATGAA 1980
CTTCAGTTGG TACAGTATCA GATTGAAGCT GGAAATGAAC TGGATTTGTT TAGTTTAAAC 2040
CCCAACTCGG GGβTATTβTC ATTAAAGCGA TCGCTAATGG ATGGCTTAGβ TGCAAAGβTG 2100
TCTTTCCACA GTCTGAGAAT CACAGCTACA GATGGAGAAA ATTTTGCCAC ACCATTATAT 2160
ATCAACATAA CAβTβGCTGC CAGTCACAAG CTββTAAACT TGCAGTGTGA AβAβACTGGT 2220
GTTGCCAAAA TGCTGGCAGA GAAGCTCCTG CAGGCAAATA AATTACACAA CCAGGGAGAG 2280
GTGGAGGATA TTTTCTTCGA TTCTCACTCT GTCAATGCTC ACATACCGCA βTTTAGAAGC 2340
ACTCTTCCGA CTGGTATTCA GGTAAAGGAA AACCAGCCTG TGGGTTCCAG TGTAATTTTC 2400
ATGAACTCCA CTGACCTTGA CACTGGCTTC AATGGAAAAC TGGTCTATGC TGTTTCTGGA 2460
GGAAATGAGβ ATAGTTGCTT CATGATTGAT ATGGAAACAG GAATGCTCAA AATTTTATCT 2520
CCTCTTGACC GTGAAACAAC AGACAAATAC ACCCTGAATA TTACCGTCTA TGACCTTGGG 2580
ATACCCCAGA AGGCTGCGTG GCGTCTTCTA CATGTCGTGG TTGTCGATGC CAATβATAAT 2640
CCACCCGAGT TTTTACAGGA GAGCTATTTT GTGGAAβTGA GTGAAGACAA GGAGGTACAT 2700
AGTGAAATCA TCCAGGTTGA AGCCACAGAT AAAGACCTGG GGCCCAACGG ACACGTGACG 2760
TACTCAATTC TTACAGACAC AGACACATTT TCAATTGACA GCGTGACGGG TGTTGTTAAC 2820
ATCGCACGCC CTCTGGATCG AGAGCTGCAG CATGAGCACT CCTTAAAGAT TGAGGCCAGG 2880
GACCAAGCCA GAGAAGAGCC TCAGCTGTTC TCCACTGTCG TTGTGAAAGT ATCACTAGAA 2940
GATGTTAATG ACAACCCACC TACATTTATT CCACCTAATT ATCGTGTGAA AGTCCGAGAG 3000
GATCTTCCAG AAGGAACCGT CATCATGTββ TTAGAAGCCC ACGATCCTGA TTTAGGTCAG 3060
TCTGGTCAGG TGAGATACAG CCTTCTGGAC CACGGAGAAG GAAACTTCGA TGTGGATAAA 3120
CTCAGTGGAG CAGTTAGGAT CGTCCAGCAG TTGGACTTTG AGAAβAAGCA AGTGTATAAT 3180
CTCACTGTGA GGGCCAAAGA CAAGGGAAAG CCAGTTTCTC TGTCTTCTAC TTGCTATGTT 3240 GAAGTTGAGG TGβTTGATGT GAATGAGAAC CTGCACCCAC CCGTGTTTTC CAGCTTTGTG 3300 GAAAAGGGGA CAGTGAAAGA AGATGCACCT GTTGGTTCAT TGGTAATGAC GGTGTCGGCT 3360 CATGATGAGG ACGCCGGAAG AGATGGGGAG ATCCβATACT CCATTAGAGA TβGCTCTGGC 3420 GTTGGTGTTT TCAAAATAGβ TGAAGAGACA GGTGTCATAG AGACGTCAGA TCGACTGGAC 3480 CCTGAATCGA CCTCCCATTA TTGGCTAACA GTCTTTGCAA CCGATCAGGG TGTCβTβCCT 3540 CTTTCATCGT TCATAGAGAT CTACATAGAG GTTGAGGATG TCAATGACAA TGCACCACAG 3600 ACATCAGAGC CTGTTTATTA CCCAGAAATC ATGGAAAATT CTCCTAAAGA TGTATCTGTG 3660 GTCCAGATCG AGGCATTTβA TCCAGATTCG AGCTCTAATG ACAAGCTCAT GTACAAAATT 3720 ACAAGTGGAA ATCCACAAGβ ATTCTTTTCA ATACATCCTA AAACAGβTCT CATCACAACT 3780 ACGTCAAGβA AGCTAGACCG AGAACAGCAA GATGAACACA TATTAGAGGT TACTGTβACA 3840 GACAATGGTA GTCCCCCCAA ATCAACCATT GCAAGAβTCA TTGTGAAAAT CCTTGATGAA 3900 AATGACAACA AACCTCAGTT TCTGCAAAAG TTCTACAAAA TCAGACTCCC TGAβCGGGAA 3960 AAGCCAGACC GAGAAAGAAA TGCCAGACGG GAGCCGCTCT ATCGCGTCAT AGCCACCGAC 4020 AAGGATGAGG GCCCCAATGC AGAAATCTCC TACAGCATCG AAGACGGGAA TβAβCATGGC 4080 AAATTTTTCA TCGAACCGAA AACTGGAGTG GTTTCGTCCA AGAGGTTTTC AβCAGCTGGA 4140 GAATATGATA TTCTTTCAAT TAAGGCAGTT GACAATGGTC GCCCTCAAAA GTCATCAACC 4200 ACCACACTCC ATATTGAATG GATCTCCAAG CCCAAACAβT CCCTGGAGCC CATTTCATTT 4260 GAAGAATCAT TTTTTACCTT TACTGTGATG GAAAGTGACC CCGTTGCTCA CATGATTGGA 4320 GTAATATCTG TGGAGCCTCC TGGCATACCC CTTTGGTTTG ACATCACTGG TGGCAACTAC 4380 GACAGTCACT TCGATGTGGA CAAGGGAACT GGAACCATCA TTGTTGCCAA ACCTCTTGAT 4440 GCAGAACAGA AGTCAAACTA CAACCTCACA GTCCAGGCTA CAGATGGAAC CACCACTATC 4500 CTCACTCAGG TATTCATCAA AGTAATAGAC ACAAATGACC ATCGTCCTCA GTTTTCTACA 4560 TCAAAGTATG AAGTTGTTAT TCCTGAAGAT ACAGCGCCAG AAACAGAAAT TTTGCAAATC 4620 AGTGGTGTGG ATCAGGATGA GAAAAACAAA CTAATCTACA CTCTGCAGAG CAGTAGAGAT 4680 CCACTGAGTC TCAAGAAATT TCGTCTTGAT CCTGCAACCG GCTCTCTCTA TACTTCTGAG 4740 AAACTGGATC ATGAAGCTGT TTCACCAGCA CACCTCACGG TCATGGTACG AGATCAAGAT 4800 GTGCCTGTAA AACGCAACTT TGCAAGGATT GTβGTCAATG TCAGCGACAC GAATGACCAC 4860 GCCCCGTGGT TCACCGCTTC CTCCTACAAA GGGCGGGTTT ATGAATCGGC AGCCGTTGGC 4920 TCAGTTGTGT TGCAGGTGAC GGCTCTGGAC AAGGACAAAG GGAAAAATGC TGAAGTGCTG 4980 TACTCGATCG AGTCAGGAAA TATTGGAAAT ATTGGAAATT CTTTTATGAT TGATCCTGTC 5040 TTGGGCTCTA TTAAAACTGC CAAAGAATTA GATCGAAGTA ACCAAGCGGA GTATGATTTA 5100 ATGGTAAAAG CTACAGATAA GGGCACTCCA CCAATGAGTG AAATAACTTC TGTGCGTATC 5160
TTTGTCACAA TTGCTGACAA CGCCTCTCCG AAGTTTACAT CAAAAGAATA TTCT6TTGAA 5220
CTTAGTGAAA CTGTCAGCAT TGGGAGTTTC GTTGGGATββ TTACAGCCCA TAGTCAATCA 5280
TCAGTGGTGT ATGAAATAAA AGATGGAAAT ACAGGTβATG CTTTTGATAT TAATCCACAT 5340
TCTGGAACTA TCATCACTCA GAAAGCCCTG GACTTTGAAA CTTTGCCCAT TTACACATTG 5400
ATAATACAAG GAACTAACAT GGCTGGTTTG TCCACTAATA CAACββTTCT AGTTCACTTG 5460
CAββATGAGA ATGACAACGC 6CCAGTTTTT ATGCAGGCAG AATATACAGG ACTCATTAGT 5520
GAATCAGCCT CAATTAACAG CGTGβTCCTA ACAGACAGGA ATGTCCCACT GGTGATTCGA 5580
GCAGCTGATG CTGATAAAGA CTCAAATβCT TTGCTTGTAT ATCACATTGT TGAACCATCT 5640
GTACACACAT ATTTTGCTAT TGATTCTAGC ACTGGTGCTA TTCATACAGT ACTAAGTCTG 5700
GACTATGAAG AAACAAGTAT TTTTCACTTT ACCGTCCAAG TGCATGACAT GGGAACCCCA 5760
CGTTTATTTG CTGAGTATGC AGCGAATGTA ACAGTACATG TAATTGACAT TAATGACTGC 5820
CCCCCTGTGT TTGCCAAGCC ATTATATGAA GCATCTCTTT TGTTACCAAC ATACAAAGGA 5880
GTAAAAGTGA TCACAGTAAA TGCTACAGAT GCTGATTCAA GTGCATTCTC ACAGTT6ATT 5940
TACTCCATCA CCGAAGGCAA CATCGβGGAG AAGTTTTCTA TGGACTACAA GACTGβTβCT 6000
CTCACTGTCC AAAACACAAC TCAGTTAAGA AGCCGCTACG AβCTAACCGT TAGAGCTTCC 6060
GATGGCAGAT TTGCCGGCCT TACCTCTGTC AAAATTAATG TGAAAGAAAG CAAAGAAAβT 6120
CACCTAAAGT TTACCCAGβA TGTCTACTCT GCGGTAGTβA AAGAGAATTC CACCGAGGCC 6180
GAAACATTAG CTGTCATTAC TGCTATTGGG AGTCCAATCA ATGAGCCTTT GTTTTATCAC 6240
ATCCTCAACC CAβATCGCAG ATTTAAAATA AGCCGCACTT CAGGββTTCT GTCAACCACT 6300
GGCACGCCCT TCGATCGTGA βCAGCAGGAG GCGTTTGATG TGGTTGTAGA AGTGATAGAG 6360
GAACATAAGC CTTCTGCAβT βGCCCACGTT GTCGTGAAGG TCATTGTAGA AGACCAAAAT 6420
GATAATGCGC CGGTGTTTβT CAACCTTCCC TACTACβCCβ TTβTTAAAβT GGACACTGAG 6480
GTGGGCCATG TCATTCGGTA TGTCACTGCT GTAGACAGAG ACAGTGGCAG AAACGGGGAA 6540
GTGCATTACT ACCTCAAGGA ACATCATGAA CACTTTCAAA TTGGACCCTT GβGTGAAATT 6600
TCACTGAAAA AGCAATTTGA GCTTGACACC TTAAATAAAG AATATCTTGT TACAGTGGTT 6660
GCAAAAGATG GAGGGAACCC GβCCTTTTCA GCGGAAGTTA TCGTTCCGAT CACTGTCATG 6720
AATAAAGCCA TGCCTGTGTT TGAAAAACCT TTCTACAGTG CAGAGATTGC AGAGAGCATC 6780
CAGGTGCACA GCCCTGTGGT CCACGTGCAG GCTAACAGCC CGGAAGGCCT GAAAGTGTTC 6840
TACAGCATCA CAGACGGAGA CCCTTTCAGC CAβTTCACTA TTAACTTCAA TACTGGAGTT 6900
ATCAATGTCA TAGCTCCTCT GGACTTTGAG GCCCACCCGG CATATAAGCT GAGCATACGC 6960
GCAACTGACT CCTTGACGGG CGCTCATGCT GAAGTATTTG TGGACATCAT AGTAGACGAC 7020
ATCAATGATA ACCCTCCTGT GTTTGCTCAG CAGTCTTATG CGGTGACCCT GTCTβAββCA 7080
TCTGTAATTG GAACGTCTGT TGTTCAAGTT AβAβCCACCβ ATTCTGATTC AGAACCAAAT 7140
AGAGGAATCT CATACCAGAT GTTTGGGAAT CACA6CAAGA GTCATGATCA TTTTCATGTA 7200
GACAGCAGCA CTGGCCTCAT CTCACTACTC AGAACCCTβG ATTACGAGCA GTCCCGGCAG 7260
CACACβATTT TTβTβAβGGC AGTTGATGGT GGTATGCCCA CGCTGAGCAG TGATGTGATT 7320
GTCACCGTGG ACGTTACCGA CCTCAATGGT AATCCACCAC TCTTTGAACA ACAGATTTAT 7380
GAAGCCAGAA TTAGCβAGCA CGCCCCTCAT GββCATTTCβ TGACCTGTGT AAAAβCCTAT 7440
GATGCAGACA GTTCAGACAT AGACAAGTTG CAGTATTCCA TTCTGTCTGG CAATGATCAT 7500
AAACATTTTG TCATTGACAG TGCAACAGGG ATTATCACCC TCTCAAACCT GCACCGGCAC 7560
GCCCTGAAβC CATTTTACAG TCTTAACCTG TCAGTGTCTG ATGGAGTTTT TAGAAβTTCC 7620
ACCCAGGTTC ATGTAACTGT AATTGGAGGC AATTTGCACA GTCCTGCTTT CCTTCAGAAC 7680
GAATATGAAG TG6AACTAGC TGAAAACGCT CCCCTACATA CCCTGGTGAT GGAββTβAAA 7740
ACTACGGATG GGGATTCTGG TATTTATGGT CACGTTACTT ACCATATTGT AAATGACTTT 7800
GCCAAAGACA GATTTTACAT AAATGAGAGA GGACAGATAT TTACTTTGGA AAAACTTGAT 7860
CGAGAAACCC CGGC66AGAA AGTβATCTCA GTCCGTTTAA TββCTAAGGA TGCTGGAGGA 7920
AAAGTTGCTT TCTGCACCGT GAATGTCATC CTTACAGATG ACAATGACAA TGCACCACAA 7980
TTTCGAGCAA CCAAATACGA AGTGAATATC GGGTCCAβTβ CTβCTAAAGG GACTTCAGTC 8040
GTAAAβTCTβ CAAGTGATGC CGATGAGGGC TCCAATGCCG ACATCACCTA TGCCATTGAA 8100
GCAGACTCTG AAAGTGTAAA AGAGAATTTG GAAATTAACA AACTGTCCGG CGTAATCACT 8160
ACAAAGGAGA GCCTCATTGG CTTGGAAAAT GAATTCTTCA CTTTCTTTGT TAGAGCTGTG 8220
GATAATGGGT CTCCATCAAA AGAATCTGTT GTTCTTGTCT ATGTTAAAAT CCTTCCACCG 8280
GAAATGCAGC TTCCAAAATT TTCAGAACCT TTCTATACCT TTACAGTGTC AGAGGACGTG 8340
CCTGTTGGAA CAGAGATAGA TCTCATCCGA GCAGAACATA GTβββACTGT TCTTTACAGC 8400
CTGGTCAAAG GGAATACTCC AGAAAGCAAT AGGGATβAβT CCTTTGTGAT TGACAGACAG 8460
AGCGGGAGAC TGAAGTTGGA GAAGAGTCTT GATCATGAGA CAACTAAGTG GTATCAGTTT 8520
TCCATACTGG CCAGGTGCAC TCAAGATGAC CATGAGATGG TGGCTTCTGT AGATGTTAGT 8580
ATCCAAGTGA AAGATβCAAA TGACAACAGC CCGGTCTTTβ AATCTAGTCC ATATGAββCA 8640
TTCATTGTTG AAAACCTGCC AGGGGGAAGT AGAGTAATTC AGATCAGGGC ATCTGATGCT 8700
GACTCAGGAA CCAACGGCCA ACTTATGTAT AGCCTGGATC AGTCACAAAG TGTGGAAGTC 8760
ATTGAATCCT TTGCCATTAA CATGβAAACA GGCTGGATTA CAACTTTAAA GGAACTTGAC 8820
CATGAAAAGA GAGACAATTA CCAGATTAAA GTGGTTGCAT CAGATCATGG TGAAAAGATC 8880
CAGCTATCCT CCACAGCCAT TGTGGATGTT ACCGTCACCG ATGTCAACGA TAGTCCACCA 8940
CGATTCACGβ CCβAβATCTA TAAAGGGACT GTGAGTGAGG ATGACCCCCA AGGTβββGTG 9000
ATTGCCATCT TAAGTACCAC GGATGCTGAT TCTGAAGAGA TCAACAGACA AGTTACATAT 9060
TTCATAACAG GAββGGATCC TTTAβGACAG TTTGCCGTTG AAACTATACA GAATGAATGG 9120
AAGGTATATG TGAAβAAACC TCTAGACAGG GAAAAAAGGG ACAATTACCT TCTTACTATC 9180
ACGGCAACTG ATGGCACCTT CTCATCAAAA βCGATAGTTG AAGTGAAAGT TCTGGATGCA 9240
AATGACAACA GTCCAGTTTG TGAAAAGACT TTATATTCAG ACACTATTCC TGAAGACGTC 9300
CTTCCTGGAA AATTGATCAT GCAGATCTCT GCTACAGACG CACACATCCβ CTCTAACβCT 9360
GAAATTACTT ACACGTTATT GGGTTCAGGT GCAGAAAAAT TCAAACTAAA TCCAGACACA 9420
GGTGAACTGA AAACGTCAAC CCCCCTTGAT CGTGAGGAGC AACCTGTTTA TCATCTTCTC 9480
GTCAGGGCCA CAGATGGAββ AGGAAGATTC TGCCAAGCCA GTATTGTCGT CACGCTAGAA 9540
GATGTGAACG ATAACGCCCC CGAATTCTCT GCCGATCCTT ATGCCATCAC CGTGTTTGAA 9600
AACACAGAGC CGGGAACGCT GCTβACAAGA GTβCAGGCCA CAGATGCCGA CGCAGGATTA 9660
AATCGGAAGA TTTTATACTC ACTGATTGAC TCTGCTGATG GGCAGTTCTC CATTAACGAA 9720
TTATCTGGAA TTATTCAGTT AGAAAAACCT TTGGACAGAG AACTCCAGGC AGTATACACC 9780
CTCTCTTTGA AAGCTGTGGA TCAAGGCTTG CCAAGGAGGC TGACTGCCAC TβGCACTCTG 9840 ATTGTATCAG TTCTTGACAT AAATGACAAC CCCCCTGTGT TTGAGTACCβ TGAATATGGT 9900 GCCACCCTGT CTGAGGACAT TCTTGTTGGA ACTGAAGTTC TTCAAGTGTA TGCAGCAAGT 9960
CGGGATATTG AAGCAAATGC AGAAATCACC TACTCAATAA TAAGTGGAAA TGAACATGGG 10020 AAATTCAGCA TAGATTCTAA AACAGGGGCC GTATTTATCA TTGAGAATCT GGATTATGAG 10080 AβCTCTCATG AGTATTACCT AACAGTAGAG GCCACTGATG GAGGCACGCC TTCACTGAGC 10140 GACGTTGCCA CTGTGAACGT TAATGTAACA GATATCAACG ATAATACCCC TβTβTTCAGC 10200
CAAGACACCT ACACGACAGT CATCAGTGAA GATGCCGTTC TTGAGCAGTC TGTCATCACG 10260
GTTATGGCCG ATGATGCCGA TGGACCTTCC AACAGCCACA TCCACTACTC AATTATAGAT 10320
GGCAACCAAG GAAGCTCGTT CACAATTGAC CCCGTCAββG GAGAAGTCAA AGTβACCAAA 10380
CTTCTCGACC GAGAAACGAT TTCAGGTTAC ACGCTCACGβ TTCAAβCTTC TGATAATGGC 10440
AGTCCACCCA GAGTCAACAC GACCACCβTG AACATCβATβ TGTCCGATGT CAATGACAAC 10500
GCGCCCGTCT TCTCCAGGGG AAACTACAGT GTCATTATCC AGGAAAATAA GCCAGTGGGC 10560
TTCAGCCTGC TGCAGCTGGT AGTAACAGAT GA6GATTCTT CCCATAACGG TCCACCCTTC 10620
TTCTTTACTA TTGTAACTGG AAATGATGAG AAGGCTTTTG AAGTTAACCC GCAAGGAGTC 10680
CTCCTGACAT CATCTGCCAT CAAGAGGAAG GAGAAAGATC ATTACTTACT GCAGGTGAAG 10740
GTGGCAGATA ATGGAAAGCC TCAGTTGTCA TCTTTGACAT ACATTGACAT TAGGGTAATT 10800
GAGGAβAβCA TCTATCCGCC TGCGATTTTG CCCCTGGAGA TTTTCATCAC CTCTTCTGGA 10860
GAAGAATACT CAGGTGGCGT CATTGGGAAG ATCCATGCCA CAGACCAGGA CGTGTATGAT 10920
ACTCTAACCT ACAGTCTCGA CCCTCAGATG GACAACCTGT TCTCTGTTTC CAGCACAGGG 10980
GGCAAGCTGA TAGCACACAA AAAGCTAGAC ATAGGGCAAT ACCTTCTCAA TGTCAGCGTA 11040
ACAGATGββA AGTTCACGAC GGTGGCCGAC ATCACAGTGC ATATCAGACA AGTCACACAG 11100
GAGATGTTGA ACCACACCAT CGCGATCCGC TTTGCCAACC TCACTCCGGA AGAATTCGTT 11160
GGTGACTACT GGCGCAACTT CCAGCGAGCT TTACGGAACA TCCTGGGTGT GAGGAGGAAC 11220
GACATACAGA TTGTTAGTTT GCAGTCCTCT GAACCTCACC CACATCTGGA CGTCTTACTT 11280
TTTGTAGAGA AACCAGGTAG TβCTCAGATC TCAACAAAAC AACTTCTGCA CAAGATTAAC 11340
TCTTCCβTβA CTGACATTGA GGAAATCATT GGAGTTAGGA TACTGAATGT ATTCCAGAAA 11400
CTCTGCGCGG GACTGGACTG CCCCTGGAAG TTCTGCGATG AAAAGGTGTC TGTGGATGAA 11460
AGTβTβATGT CAACACACAG GACAGCCAGA CTGAGTTTTG TGACTCCCCG CCACCACAGG 11520
GCAGCGGTGT GTCTCTGCAA AGAGGGAAGG TGCCCACCTG TCCACCATGG CTGTGAAβAT 11580
GATCCGTGCC CTGAGGGATC CGAATGTGTG TCTGATCCCT GGGAGβAGAA ACACACCTGT 11640
GTCTGTCCCA GCGGCAGGTT TGGTCAGTGC CCAGGGAGTT CATCTATGAC ACTGACTGGA 11700
AACAGCTACG TGAAATACCG TCTGACGGAA AATGAAAACA AATTAGAGAT GAAACTGACC 11760
ATGAGβCTCA GAACATATTC CACGCATGCG βTTGTCATGT ATGCTCGAGG AACTGACTAT 11820
AGCATCTTGG AGATTCATCA TGGAAGGCTG CAGTACAAGT TTGACTGTGG AAGTGGCCCT 11880
GGAATTGTCT CTGTTCAGAG CATTCAGGTC AATGATGGβC AGTGGCACGC AGTGGCCCTG 11940
GAAGTGAATG GAAACTATGC TCGCTTGGTT CTAGACCAAG TTCATACTGC ATCGGβCACA 12000
GCCCCAGGGA CTCTGAAAAC CCTGAACCTG GATAACTATG TGTTTTTTGG TGGCCACATC 12060
CGTCAGCAGG GAACAAGβCA TGGAAGAAGT CCTCAAGTTG GTAATGGTTT CAGGGGTTGT 12120
ATGβACTCCA TTTATTTGAA TGGGCAGGAG CTCCCTTTAA ACAGCAAACC CAGAAGCTAT 12180
GCACACATCG AAGAGTCGGT GGATGTATCT CCAGGCTGCT TCCTGACGGC CACGGAAGAC 12240
TGCGCCAGCA ACCCTTGCCA GAATGβAββC GTTTGCAATC CGTCACCTGC TGGAGGTTAT 12300
TACTGCAAAT GCAGTGCCTT GTACATAGGG ACCCACTGTG AGATAAGCGT CAATCCβTGT 12360
TCCTCCAACC CATGCCTCTA TGGGGGCACG TGTGTTGTCG ACAACGGAGG CTTTGTTTGC 12420
CAGTGTAGAG GATTATATAC TGGTCAβAβG TGTCAGCTTA GTCCATACTG CAAAGATGAA 12480
CCCTGTAAGA ATGGCGGAAC ATGCTTTGAC AGTTTGGATG GCGCCGTTTG TCAGTGTGAT 12540
TCGGGTTTTA GGGGA6AAAG GTGTCAβAβT GATATCGACG AGTGCTCTGG AAACCCTTGC 12600
CTGCACGGGG CCCTCTGTGA GAACACGCAC GGCTCCTATC ACTGCAACTG CAGCCACGAG 12660
TACAGGGGAC GTCACTGCGA GGATGCTβCG CCCAACCAGT ATGTGTCCAC GCCGTGGAAC 12720
ATTGGGTTGG CGGAAGGAAT TGGAATCGTT βTGTTTGTTG CAGGGATATT TTTACTGGTG 12780
GTGGTβTTTG TTCTCTGCCG TAAGATGATT AGTCGGAAAA AGAAGCATCA GGCTGAACCT 12840
AAAGACAAGC ACCTGGGACC CGCTACGGCT TTCTTGCAAA GACCGTATTT TGATTCCAAG 12900
CTAAATAAGA ACATTTACTC AGACATACCA CCCCAGGTGC CTGTCCGGCC TATTTCCTAC 12960
ACCCCGAGTA TTCCAAGTβA CTCAAGAAAC AATCTGGACC GAAATTCCTT CβAAGGATCT 13020
GCTATCCCAC AGCATCCCβA ATTCAGCACT TTTAACCCCG AGTCTGTGCA CGββCACCGA 13080
AAAGCAGTGG CGGTCTGCAG CGTGGCGCCA AACCTGCCTC CCCCACCCCC TTCAAACTCC 13140
CCTTCTGACA GCGACTCCAT CCACAAβCCT AGCTGGGACT TTGACTATGA CACAAAACTG 13200
GTGGATCTTG ATCCCTGTCT TTCCAAGAAG CCTCTAGAGG AAAAGCCTTC CCAGCCATAC 13260
AGTGCCCGGG AAAGCCTGTC TGAAGTGCAG TCCCTGAGCT CCTTCCAGTC CGAATCGTGC 13320
GATβACAATG GGTATCACTG GβATACATCA GATTGGATGC CAAGCGTTCC TCTGCCGGAC 13380
ATACAAGAGT TCCCCAACTA TGAGGTGATT GATGAGCAGA CACCCCTGTA CTCAGCAGAT 13440
CCAAACGCCA TCGATACGGA CTATTACCCT GGAGGCTACG ACATCGAAAG TGATTTTCCT 13500
CCACCCCCAG AAGACTTCCC CGCAβCTGAT GAGCTACCAC CGTTACCGCC CGAATTCAGC 13560
AATCAGTTTG AATCCATCCA CCCTCCTAGA GACATGCCTG CCGCGGβTAG CTTGGGTTCT 13620
TCATCAAGAA ACCGβCAGAG GTTCAACTTG AATCAGTATT TGCCCAATTT TTATCCCCTC 13680
GATATGTCTG AACCTCAAAC AAAAGGCACT GGTGAGAATA GTACTTGTAG AGAACCCCAT 13740
GCCCCTTACC CGCCAGGGTA TCAAAGACAC TTCGAGGCGC CCGCTGTCGA GAGCATGCCC 13800
ATGTCTGTβT ACGCCTCCAC CGCCTCCTGC TCTGACGTβT CAGCCTGCTG CGAAGTGβAG 13860
TCCGAGGTCA TGATGAGTGA CTATGAGAGC GGGGACGACG GCCACTTCGA AGAGGTGACG 13920
ATCCCGCCCC TGGATTCCCA GCAGCACACG GAAGTCTGAC TCTCAACTCC CCCCAAAGTG 13980
CCTGACTTTA GTGAACCTAG AGCTGATGTG AGTAATCCGC GCTGTTCTTT GCAGCAGTGC 14040 TTCCAAGCTT TTTTTGGTGA GCCGAATGββ CATGGCTGCG CTGGATCCTG CGCCTCTGGA 14100
CGTGCTAGCC ATTTCCAGTG TCCCAACTAC TGTCATCGTG AGGTTTTCAT CGGCTGTGCC 14160 ATTTCCCAAC GTCTTTTGGG ATTTACATCT GTCTGTGTTA AAATAATCAA ACGAAAAATC 14220 AGTCCTGTGT TGTCAGCATG ATTCATGTAT TTATATAGAT TTGATTATTT TAATTTTCCT 14280 GTCTCTTTTT TTTGTAAATT TTATGTACAG ATTTGATTTT TCATAGTTTT AACTAGATTT 14340 CCAAGATATT TTGTGCATTT GTTTCAACTG AATTTTGGTG GTGTCAGTβC CATTATCTAG 14400 CACCCTGATT TTTTTTTTTT TACTATAACC AGGGTTTCAT TCTGTCTTTT TCCACTGAAG 14460 TGTGACATTT TGTTAGTACA TTTCAGTGTA GTCATTCATT TCTAGCTGTA CATAGGATGA 14520 AGGAGAGATC AGATACATGA ACATGTCTTA CATGGGTTGC TGTATTTAGA ATTATAAACA 14580 TTTTTCATTA TTGβAAAβTβ TAACGGGGAC CTTCTGCATA CCTGTTTAGA ACCAAAACCA 14640 CCATGACACA GTTTTTATAG TGTCTGTATA TTTGTGATGC AATGGTCTTG TAAAGGTTTT 14700 TAATGAAAAC TACCATTAGC CAGTCTTTCT TACTGACAAT AAATTATTAA TAAAAT 14756 Seq ID NO: C161 DNA Sequence Nucleic Acid Accession ft: NM_014220.1 Coding sequence: 102..710
11 21 31 51 I GTGGTGTTTG CTTTCTCCAC CAGAAβGGCA CACTTTCATC TAATTTGGGG TATCACTGAG 60
CTGAAGACAA AGAGAAGGGG GAGAAAACCT AGCAGACCAC CATGTGCTAT GGGAAGTGTG 120
CACGATGCAT CGGACATTCT CTGGTGGGGC TCGCCCTCCT βTβCATCGCG GCTAATATTT 180
TGCTTTACTT TCCCAATGGG GAAACAAAGT ATGCCTCCGA AAACCACCTC AGCCGCTTCG 240
TGTGGTTCTT TTCTGGCATC GTAGGAGGTG GCCTGCTGAT GCTCCTGCCA GCATTTGTCT 300
TCATTGGβCT GGAACAββAT GACTGCTGTG GCTGCTGTGG CCATGAAAAC TGTGGCAAAC 360
GATGTGCGAT ecTTTCTTCT GTATTGGCTβ CTCTCATTGG AATTGCAGGA TCTGGCTACT 420
GTGTCATTGT GGCAGCCCTT GGCTTAGCAG AAGGACCACT ATGTCTTGAT TCCCTCGGCC 480
AGTGGAACTA CACCTTTGCC AGCACCGAGβ GCCAβTACCT TCTGGATACC TCCACATGGT 540
CCGAGTGCAC TGAACCCAAG CACATTβTββ AATGGAATGT ATCTCTGTTT TCTATCCTCT 600
TGGCTCTTGG TGGAATTGAA TTCATCTTGT GTCTTATTCA AβTAATAAAT GGAGTGCTTG 660
GAGGCATATG TGGCTTTTGC TGCTCTCACC AACAGCAATA TβACTβCTAA AAGAACCAAC 720
CCAGGACAGA GCCACAATCT TCCTCTATTT CATTGTAATT TATATATTTC ACTTGTATTC 780
ATTTGTAAAA CTTTGTATTA GTGTAACATA CTCCCCACAG TCTACTTTTA CAAACGCCTG 840
TAAAGACTGG CATCTTCACA GGATGTCAβT βTTTAAATTT AGTAAACTTC TTTTTTGTTT 900
GTTTATTTGT TTTTGTTTTT TTTTAAGGAA TGAGGAAACA AACCACCCTC TGGGGGTAGT 960
TTACAGACTG AGTGACAGTA CTCAGTATAT CTGAGATAAA CTCTATAATG TTTTGGATAA 1020
AAATAACATT CCAATCACTA TTGTATATAT GTGCATGTAT TTTTTAAATT AAAGATGTCT 1080
AGTTGCTTTT TATAAGACCA AGAAGGAGAA AATCCGACAA CCTGGAAAGA TTTTTGTTTT 1140
CACTGCTTGT ATGATGTTTC CCATTCATAC ACCTATAAAT CTCTAACAAG AGGCCCTTTG 1200
AACTGCCTTG TGTTCTGTGA GAAACAAATA TTTACTTAGA GTGGAAGGAC TGATTGAGAA 1260
TGTTCCAATC CAAATGAATG CATCACAACT TACAATGCTG CTCATTGTTG TGAGTACTAT 1320
GAGATTCAAA TTTTTCTAAC ATATGGAAAG CCTTTTGTCC TCCAAAGATG AGTACTAGGG 1380
ATCATGTGTT TAAAAAAAGA AAββCTACGA TGACTGGGCA AGAAGAAAGA TGGβAAACTβ 1440
AATAAAGCAG TTGATCAGCA TCATTGGAAC ATGGGGACGA GTGACGGCAG GAGGACCACG 1500
AGGAAATACC CTCAAAACTA ACTTGTTTAC AACAAAATAA AGTATTCACT ACGAAAAAAA 1560
AAAAAAAAAA AAAAAAAAAA AAA 1583
Seq ID NO: C162 DNA Sequence Nucleic Acid Accession # : NM_003759.1
Coding sequence : 150. .3257
1 11 21 31 41 51
I I I I I I
GTTCTTTGTG ACACATCACA CAGAATTGGA GTGCTGTCCT TCTGGAGAGT GGTGGAGAAC 60
CAAGATACAG TTCAGAACCA AAGGAATAGA GAAGGGCTTT GATTTCTTTT TGGCTTTAGA 120
TTGGGGATTT GGGAGGCTTA GCAGβAAAβA TGTCCACTGA AAATGTGGAA GGGAAGCCCA 180
GTAACCTTGG GGAGAGAGGA AGAβCCCGGA GCTCCACTTT CCTCAGGGTT GTCCAGCCAA 240
TCTTTAACCA CAGTATTTTC ACTTCTGCAG TCTCTCCTGC TGCAGAACGC ATCCGATTCA 300
TCTTGGGAGA GGAGGATGAC AGCCCAβCTC CCCCTCAβCT CTTCACGGAA CTGGATGAGC 360
TGCTGGCCGT GGATGββCAG GAGATGGAGT GGAAGGAAAC AGCCAGGTGG ATCAAGTTTG 420
AAGAAAAAβT GGAACAGCGT GGβGAAAGAT GGAGCAAβCC CCATGTGGCC ACATTGTCCC 480
TTCATAGTTT ATTTGAβCTG AG6ACATGTA TGGAGAAAGβ ATCCATCATG CTTGATCGGG 540
AGGCTTCTTC TCTCCCACAG TTGGTGGAGA TGATTGTTGA CCATCAGATT GAGACAGGCC 600
TATTGAAACC TGAACTTAAG GATAAGGTGA CCTATACTTT GCTCCGGAAβ CACCGGCATC 660
AAACCAAGAA ATCCAACCTT CGGTCCCTGG CTGACATTGG GAAGACAGTC TCCAβTGCAA 720
GTAGGATGTT TACCAACCCT GATAATGGTA GCCCAGCCAT GACCCATAGG AATCTGACTT 780
CCTCCAGTCT GAATGACATT TCTGATAAAC CGGAGAAGGA CCAGCTGAAβ AATAAGTTCA 840
TGAAAAAATT GCCACGTGAT GCAGAAGCTT CCAACGTGCT TGTTG6GGAG GTTGACTTTT 900
TGGATACTCC TTTCATTGCC TTTGTTAGGC TACAGCAGGC TGTCATGCTG GGTGCCCTGA 960
CTGAAGTTCC TGTβCCCACA AββTTCTTβT TGATTCTCTT AGGTCCTAAG GGGAAAGCCA 1020
AGTCCTACCA CGAGATTGGC AGAβCCATTG CCACCCTGAT GTCTGATGAG GTGTTCCATG 1080
ACATTGCTTA TAAAGCAAAA GACAGGCACG ACCTGATTGC TGGTATTGAT GAGTTCCTAG 1140
ATGAAGTCAT CGTCCTTCCA CCTGGGGAAT GGGATCCAGC AATTAGGATA GAGCCTCCTA 1200
AGAGTCTTCC ATCCTCTGAC AAAAGAAAGA ATATGTACTC AGGTGGAβAG AATGTTCAβA 1260
TGAATG6GGA TACGCCCCAT GATGGAGGTC ACGGAGGAGG AGGACATGGG GATTβTGAAG 1320
AATTGCAGCG AACTGGACGG TTCTGTGGTG GACTAATTAA AGACATAAAG AGGAAAGCGC 1380
CATTTTTTGC CAGTGATTTT TATGATGCTT TAAATATTCA AGCTCTTTCG GCAATTCTCT 1440
TCATTTATCT GGCAACTGTA ACTAATGCTA TCACTTTTGG AGGACTGCTT GGGGATGCCA 1500
CTGACAACAT GCAGGβCGTG TTGβAβAβTT TCCTGGβCAC TβCTGTCTCT GGAGCCATCT 1560
TTTGCCTTTT TGCTGβTCAA CCACTCACTA TTCTGAβCAβ CACCGGACCT GTCCTAGTTT 1620
TTGAGAGGCT TCTATTTAAT TTCAGCAAGG ACAATAATTT TGACTATTTG GAGTTTCGCC 1680
TTTGGATTCG CCTGTGGTCC GCCTTCCTAT GTCTCATTTT GGTAGCCACT GATGCCAGCT 1740
TCTTGGTTCA ATACTTCACA CGTTTCACGG AGGAGGGCTT TTCCTCTCTG ATTAβCTTCA 1800
TCTTTATCTA TGATGCTTTC AAGAAβATβA TCAAGCTTGC AGATTACTAC CCCATCAACT 1860
CCAACTTCAA AGTGGGCTAC AACACTCTCT TTTCCTGTAC CTCTGTGCCA CCTGACCCAG 1920
CTAATATCTC AATATCTAAT GACACCACAC TGGCCCCAGA GTATTTGCCA ACTATGTCTT 1980
CTACTGACAT GTACCATAAT ACTACCTTTG ACTGGGCATT TTTGTCGAAG AAGGAGTGTT 2040
CAAAATACGG AGβAAACCTT GTCGGGAACA ACTGTAATTT TGTTCCTGAT ATCACACTCA 2100
TGTCTTTTAT CCTCTTCTTG GGAACCTACA CCTCTTCCAT GGCTCTGAAA AAATTCAAAA 2160
CTAGTCCTTA TTTTCCAACC ACAGCAACAA AACTGATCAβ TGATTTTGCC ATTATCTTGT 2220
CCATTCTCAT CTTTTGTGTA ATAGATGCCC TAGTAGGCGT GGACACCCCA AAACTAATTG 2280
TGCCAAGTGA CTTCAAGCCA ACAAGTCCAA ACCGAGβTTβ GTTCGTTCCA CCGTTTGGAG 2340
AAAACCCCTG GTGGGTGTβC CTTGCTGCTG CTATCCCGGC TTTGTTGGTC ACTATACTGA 2400
TTTTCATGGA CCAACAAATT ACAGCTGTGA TTGTAAACAG GAAAGAACAT AAACTCAAGA 2460
AAGGAGCAGG GTATCACTTG GATCTCTTTT GGGTGGCCAT CCTCATGGTT ATATGCTCCC 2520
TCATGβCTCT TCCGTGGTAT GTAGCTGCTA CGGTCATCTC CATTGCTCAC ATCGACAGTT 2580
TGAAGATGGA GACAGAGACT TCTGCACCTG GAGAACAACC AAAGTTTCTA GGAGTGAGGG 2640
AACAAAGAGT CACTGβAACC CTTβTGTTTA TTCTGACTGG TCTGTCAGTC TTTATGGCTC 2700
CCATCTTGAA GTTTATACCC ATGCCTGTAC TCTATGGTGT GTTCCTGTAT ATGGGAGTAG 2760
CATCCCTTAA TGGTGTGCAG TTCATGGATC GTCTGAAβCT GCTTCTGATG CCTCTGAAGC 2820
ATCAGCCTGA CTTCATCTAC CTGCGTCATG TTCCTCTCCG CAGAGTCCAC CTGTTCACTT 2880
TCCTGCAβGT GTTGTGTCTG GCCCTGCTTT GGATCCTCAA GTCAACGGTG GCTGCTATCA 2940
TTTTTCCAGT AATGATCTTG GCACTTGTAG CTGTCAβAAA AGGCATGGAC TACCTCTTCT 3000 CCCAGCATGA CCTCAGCTTC CTGGATGATG TCATTCCAGA AAAGGACAAG AAAAAGAAGG 3060
AGGATGAGAA GAAAAAGAAA AAGAAGAAββ GAAGTCTGGA CAGTGACAAT GATGATTCTG 3120
ACTGCCCATA CTCAGAAAAA GTTCCAAGTA TTAAAATTCC AATGGACATC ATGGAACAGC 3180
AACCTTTCCT AAGCGATAGC AAACCTTCTG ACAGAGAAAG ATCACCAACA TTCCTTGAAC 3240
GCCACACATC ATGCTGATAA AATTCCTTTC CTTCAGTCAC TCGGTATGCC AAGTCCTCCT 3300
AGAACTCCAG TAAAAGTTGC CTCAAATTAG ACTAGAACTT GAACCTGAAG ACAATGATTA 3360
TTTCTGGAGG AGCAAGGGAA CAGAAACTAC ATTGTAACCT GTTTGTCTTT CTTAAAACTG 3420
ACATTTGTTG TTAATGTCAT TTGTTTTTGT TTGGCTGTTT GTTTATTTTT TAACTTTTAT 3480
TTCGTCTCAG TTTTTGGTCA CAGGCCAAAT AATACAGCGC TCTCTCTGCT TCTCTCTTGC 3540
ATAGATACAA TCAAGACAAT AGTGCACCGT TCCTTAAAAA CAGCATCTGA GGAATCCCCC 3600
TTTTGTTCTT AAACTTTCAG ATGTGTCCTT TGATAACCAA ATTCTGTCAC TCAAGACACA 3660
GACACCCACA GACCCTGTCC TTTGCCTCTA TTAAGCAGAG GATGGAAGTA TTAAGGATTT 3720
TGTAACACCT TTTATGAAAA TGTTGAAGGA ACTTAAAACT TTAGCTTTGG AGCTGTGCTT 3780
ACTGGCTTGT CTTTGTCTGG TAGAACAAAC CTTGACCTCC AGACAGAGTC CCTTCTCACT 3840
TATAGAGCTC TCCAGGACTG GAAAAAGTGC TGCTATTTTA ACTTCCTCTT GCTTGTAAAT 3900
CCTAATCTTA GAGTTATCAA AAGAAGAAAA AACTGAAGGT ACTTTACTCC CTATAGAGAA 3960
ACCATTGCCA TCATTGTAGC AAGTGCTGGA ATGTCCCTTT TTTCCTATGC AACTTTTTTA 4020
TAACCCTTTA ATGAACTTAT CTGTGGAGTA CATTGAAGAA TATTTTTCTT CCTAGATTTT 4080
GTTGTTTAAA TTATGGGGCC TAACCTGCCA CTTATTTTTT GTCAATTTTT AAAACTTTTT 4140
TTTAATTACT GTAAAGAAAA TGAATTTTTT CCTGCAGCAG GAAACATAGT TTTCAGTAGT 4200
TCTACCTCTT ATTTGTAGCT GCCAGGCTTT CTGTAAAAAT TGTATTGTAT ATAATGTGAT 4260
TTTTACACAT ACATACACAC ACAAATACAC AATCTCTAGG GTAAGCCAGA AGGCAAGATC 4320
AGATTAAAAA CACCATGTTT CTAAGCATCC ATTTTTCCCT TTCTTTAAAA GAAACTTAAC 4380
TGTTCTATGA AGGAGATTGA GGGAGAAGAG ACAAACTCCT ATGTCATGAG AATAACCGAT 4440
GTTCTGATAA TAGTAGCATC TAGGTACAGA TGCTGGTTGT ATTACCACGT CAATGTCCTA 4500
TGCAGTATTG TTAGACATTT TCTCATTTTG AAATATTTβT βTGTTTGTGT ATGTGCTCTG 4560
TGCCATβGCT GGTGTATATA TGTGCAATGT TAβAAGGCAA AAGAGTGATβ GTAGGCAGAG 4620
GGCAAAGTCA TTGAATCTCT TATGCCAGTT TTCATAAAAC CCAAACCACA TATGAAAAAA 4680
TCCATTAAGG GTCCAAGAAG TCTGTCCATA TGAAAATGAG GGTAAATATA GTTTATTTCC 4740
CAGGTATCAG TCATTATAAT TGATATAATA GCTCTAACAT GCAATATAAA ATTCATAGGA 4800
GTATTAATAG CCCATTTACA CATCTATAAA ATGTAATGGG ATTGCAGAGC TGCAGAGTAC 4860
AGTβTAACAG TACTCTCATG CAATTTTTTT CAGGATGCAA AGGCAATTAT TCTTTβTAAG 4920
CGGGACATTT AGATATATTT GTGTACATAT TATATGTATG TATATTTCAA AGTACCACAC 4980
TGAAAATTAG ACATTTATTA ACCAAATTTA ACGTGGTATT TAAAGGTAAT ATTTTTAATA 5040
TGATACATTA CATATTGTβA ATGTATACTA AAAAAACATT TTAAATGTTA AAATTATAAT 5100
TTCAGATTCA TATAACCACA ACTGTGATAT ATCCTAACTA TAACCAGTTG TTGAβββGTA 5160
TACTAGAAGC AGAATGAAAC CACATTTTTT GGTTTGATAA TATGCACTTA TTGACTCCCA 5220
CTCATTGTTA TGTTAATTAA GTTATTATTC TGTCTCCTTG TAATTTTGAT TACAAAAATT 5280
TTATTATCCT GAGTTAGCTG TTACTTTTAC AGTACCTGAT ACTCCTAAAA CTTTTAACTT 5340
ATACAAATTA βTCAATAATβ ACCCCAATTT TTTCATTAAA ATAATAGTGG TGAATTATAT 5400
GTTATTGTGT TAAAACCTCA CTTGCCAAAT TCTGGCTTCA CATTTGTATT TAGGGCTATC 5460
CTTAAAATGA TGA6TCTATA TTATCTAGCT TTCTATTACC CTAATATAAA CTGGTATAAG 5520
AAGACTTTCC TTTTTTCTTT ATGCATGGAA GCATCAATAA ATTGTTTAAA AACCATGTAT 5580
AGTAAATTCA GCTTAACCCG TGATCTTCTT AAGTTAAAGG TACTTTTGTT TTATAAAAβC 5640
TCTAGATAAA ACTTTCTTTT CTGATCATGA ATCAAGTATC TGTGGTTTCA TGCCCCTCTC 5700
TATACCTTTC AAAGAACTCC TGAAGCAACT TAACTCATCA TTTCAGCCTC TGAGTAGAGG 5760
TAAAACCTAT GTGTACTTCT GTTTATGATC CATATTGATA TTTATGACAT GAACACAGAA 5820
TAGTACCTTA CATTTGCTAA ACAβACAβTT AATATCAAAT CCTTTCAATA TTCTGGGAAC 5880
CCAGGGAAGT TTTTAAAAAT GTCATTACTT TCAAAGGAAC AGAAGTACTT AACCAAACTA 5940
ACAAGCAAAA CCTβAββTTT ACCTAGTGAC ACCAAATTAT CGGTATTTTA ACTGAATTTA 6000 CCCATTGACT AAGAATGAAC CGGATTTGGT GGTGGTTTTG TTTCTATGCA AACTGGACAC 6060 AAATTACAAC AGTAAATTTT TTTATAAGTG CTTCTCCCTT CTCCATGATC TGACTTCCGG 6120 AGATAAAGGA TTCAAAAGAT AAAGACAAAG TACGCTCAGA 6TTGTTAACC AGAAAGTCCT 6180 GGCTGTGGTT GCAGAAACAC TGTTGGAAGA AAAGA6ATGA CTAAGTCAAG TGTCTβCCTT 6240 ATCAAAAGAG CAAAAATGCC TCTGGTTTTG TGTTTGGGAG AAAAATATCT TGGACGCACT 6300 GTTTTCCTTG ATAAAAGTCA TCTTCTCTAC TGTGTGAAAT GAATACTTGG AATTCTAATT 6360 GTTTTGTGTG CCAGGGGCAG TAATGTCCCT GCCTCTTCTC CCAATCAAGG TTGAββAGTG 6420 GGGCTGGGGA GAGGACTTAA CTGACTTAAG AAGTAGGAAA ACAAAAACCT CTCTCCTCAG 6480 CCTTCCACCT CCAAGAGAββ AGGAAAAACA GTTGTCTGCT GTCTGTAATT CAGTTTGCGT 6540 GTATTTTATG CTCATGCACC AACCCATACA GAGTAAATCT TTTATCAACT ATATACTGGT 6600 βTTTAATAβA GAATGATTGT CTTCCGAGTT TTTTGGTTCC TTTTTTAACT GTGTTAAAGT 6660 ACTTGAAATG TATTGACTGC TGACTATATT TTAAAAACAA AATGAAATAA TTTGAβTTGT 6720 ATTACAGAGG TTGACATTGT TCAGGGATGG GACAAAGCCT TCTTCAATCC TTTTCATACT 6780 ACTTAATGAT TTTGGTGCAG GAACCTGAGA TTTTCTGATT TATATTTCAT GATATTTCAC 6840 ATTTGCTCTT CACAGCATGA GCATβAAGCC CAGTβGCACC AAATGGCTGβ GTACAATCAA 6900 GTGATATTTT GTAGCACCTC ACTATCTGAA AGGCCATGAG TTTTCAβATG ATTTCATTGA 6960 GCTTCATTGC AGCCTGAAAT TTTAAAAAAG TTGTGTAATA CGCCAACCAG TCAAGTTGTG 7020 TTTTGGCCAG AGATTTAGAT ATGTCCAATT TCCTGGCTCA TTTCATTGTβ CTCTATGGGT 7080 ACGTATAAAA AGCAAGAATT CTGTTTCCTA GGCAAACATT GCAACTCAGG GCTAAAGTCA 7140 TCCA6TGAAA CTTTTAGAGC CAGAAGTAAC TTTGTCCCAG TCCTACAATG TGAAAAGAGT 7200 βAATAGTTGC CTCTTTTTAβ CCATTTTCAT GGCTGGTACA TATTCGTACG CATTACTTTT 7260 CAGAATCAAT ACGCACTTTC AGATATTCTT ATTTTTATTC TCTTAAGTCT TTATTAACTT 7320 TGGAGAGAGA AATGATGCAT CTTTTTATTT TAAATGAAGT AGATCAACAT GGTGGAACAA 7380 AATGATAAAG AACAGAAAAC ATTTCAATAT ATTACTAATA ACTTTTTCCA ATATAAATCC 7440 TAAAATTCCT ATAACATAGT ATTTTACAGT TTTATGAAGC TTTCTATTGT GACTTTTATG 7500 GAATTAAβAG ATGAAGAAGA TGAGATATTT TAGCATTTAT ATTTTTCAAA ATTATATGTA 7560 TACTTAAAAA TAAAGTAACT TTATGC 7586
Seq ID NO: C163 DNA Sequence Nucleic Acid Accession ft: NM_000958 Coding sequence: 389..1855
11 21 31 I CGGCACAGCC TCACACCTβA ACGCTGTCCT CCCGCAGACG AGACCGGCGG GCACTGCAAA 60
GCTGGGACTC GTCTTTGAAG GAAAAAAAAT AGCGAGTAAG AAATCCAGCA CCATTCTTCA 120
CTGACCCATC CCGCTGCACC TCTTGTTTCC CAAGTTTTTG AAAGCTGGCA ACTCTGACCT 180
CGGTGTCCAA AAATCGACAG CCACTGAGAC CGGCTTTGAG AAβCCGAAGA TTTGGCAGTT 240
TCCAGACTGA GCAGGACAAG GTGAAAGCAG βTTGGAGGCG GGTCCAGGAC ATCTGAGGGC 300
TGACCCTGβG GGCTCGTGAG GCTGCCACCG CTGCTGCCGC TACAGACCCA GCCTTGCACT 360
CCAAGGCTGC βCACCGCCAG CCACTATCAT GTCCACTCCC GβββTCAATT CGTCCGCCTC 420
CTTGAβCCCC GACCGGCTGA ACAGCCCAGT GACCATCCCG GCGGTGATGT TCATCTTCGG 480
GGTGGTGGGC AACCTGGTGG CCATCGTGGT GCTGTGCAAG TCGCGCAAGβ AGCAGAAGGA 540
GACGACCTTC TACACGCTGG TATGTGβGCT βGCTGTCACC βACCTGTTGG GCACTTTGTT 600
GGTGAGCCCG GTGACCATCG CCACGTACAT βAAββGCCAA TββCCCGGGG GCCAβCCGCT 660
GTGCGAGTAC AGCACCTTCA TTCTGCTCTT CTTCAGCCTG TCCGGCCTCA GCATCATCTG 720
CGCCATGAGT GTCGAβCGCT ACCTCβCCAT CAACCATGCC TATTTCTACA GCCACTACGT 780
GGACAAGCGA TTGGCGGGCC TCACGCTCTT TGCAGTCTAT GCGTCCAACG TGCTCTTTTG 840
CGCGCTβCCC AACATGGGTC TCGGTAGCTC GCGGCTGCAG TACCCAGACA CCTGGTGCTT 900
CATCGACTGG ACCACCAACG TGACGGCGCA CGCCGCCTAC TCCTACATGT ACGCGGGCTT 960
CAGCTCCTTC CTCATTCTCG CCACCGTCCT CTGCAACGTG CTTGTGTGCG GCGCGCTGCT 1020
CCGCATGCAC CGCCAGTTCA TGCGCCGCAC CTCGCTGGGC ACCGAGCAGC ACCACGCGGC 1080
CβCGGCCGCC TCGGTTGCCT CCCGGGGCCA CCCCGCTCCC TCCCCAGCCT TGCCGCGCCT 1140
CAGCGACTTT CGGCβCCGCC GGAGCTTCCG CCGCATCGCG GGCGCCβAGA TCCAGATβGT 1200
CATCTTACTC ATTGCCACCT CCCTGGTGGT GCTCATCTGC TCCATCCCGC TCGTGGTGCG 1260
AGTATTCGTC AACCAGTTAT ATCAGCCAAβ TTTGGAGCGA GAAGTCAGTA AAAATCCAGA 1320
TTTGCAGGCC ATCCGAATTG CTTCTβTGAA CCCCATCCTA GACCCCTGGA TATATATCCT 1380
CCTGAGAAAG ACAGTGCTCA GTAAAGCAAT AGAGAAGATC AAATGCCTCT TCTGCCGCAT 1440
TGGCGGGTCC CGCAGGGAGC GCTCCGGACA GCACTGCTCA GACAGTCAAA GGACATCTTC 1500
TGCCATGTCA GGCCACTCTC GCTCCTTCAT CTCCCGGGAG CTGAAGGAGA TCAGCAGTAC 1560
ATCTCAGACC CTCCTGCCAG ACCTCTCACT GCCAGACCTC AGTGAAAATG GCCTTGβAβG 1620
CAGGAATTTG CTTCCAGGTG TGCCTGGCAT GGGCCTGGCC CAGGAAGACA CCACCTCACT 1680
GAGβACTTTβ CGAATATCAG AGACCTCAGA CTCTTCACAG GGTCAGGACT CAGAGAGTGT 1740
CTTACTGGTG GATGAGGCTG GTGββAGCGG CAGGGCTGGβ CCTGCCCCTA AGGGGAGCTC 1800
CCTGCAAGTC ACATTTCCCA GTGAAACAGT GAACTTATCA GAAAAATGTA TATAATAGGC 1860
AAGGAAAGAA ATACAGTACT GTTTCTGGAC CCTTATAAAA TCCTβTCCAA TAGACACATA 1920
CATGTCACAT TTAGCTGTGC TCAGAAGGGC TATCATCA 1958
Seq ID NO: C164 DNA Sequence
Nucleic Acid Accession ft: NM_002659.1
Coding sequence: 427..1434
1 11 21 31 41 51 1 1 1 1 | 1 1 | 1 I 1
CAGTATCCCT CCTGACAAAA CTAACAAAAA TCCTGTTAGC CAAATAATCA βCCACATTCA 60
TATTTACCGT CAAAGTTTTT ATCCTCATTT TACAGCAGTG GAGAGCGATT GCCCCGβGTC 120
CCAC6TTAGG AAGAGAGAGA ACTGGGATTT GCACCCAGGC AATCTGGGGA CAGAGCTGTG 180
ATCACAACTC CATGAGTCAG GGCCGAGCCA GCCCCTTCAC CACCAGCCGG CCGCβCCCCG 240
GGAAGGAAGT TTGTGGCβGA GGAGGTTCGT ACGGGAGβAG GGGGAGGCGC CCACGCATCT 300
GGGGCTGACT CGCTCTTTCG CAAAACGTCT GGGAGGAβTC CCTGGGGCCA CAAAACTGCC 360
TCCTTCCTGA GβCCAβAAβG AGAGAAGACG TGCAGGGACC CCGCGCACAG GAGCTGCCCT 420
CGCGACATGG GTCACCCGCC GCTGCTGCCG CTGCTβCTGC TGCTCCACAC CTGCGTCCCA 480
GCCTCTTGGG GCCTGCGGTG CATGCAGTGT AAGACCAACG GGGATTGCCG TGTGβAAβAG 540
TGCGCCCTGG GACAGGACCT CTGCAGGACC ACGATCGTGC GCTTGTGGGA AGAAGGAGAA 600
GAGCTGGAGC TGGTGGAGAA AAGCTGTACC CACTCAGAGA AGACCAACAG GACCCTGAGC 660
TATCGGACTG GCTTGAAGAT CACCAGCCTT ACCGAGGTTG TGTGTGGGTT AGACTTGTGC 720
AACCAGGGCA ACTCTGGCCG GGCTβTCACC TATTCCCGAA GCCGTTACCT CGAATGCATT 780
TCCTGTGGCT CATCAGACAT GAGCTGTGAG AGGGGCCGβC ACCAGAGCCT GCAGTGCCGC 840
AGCCCTGAAG AACAβTGCCT GGATGTGGTG ACCCACTGGA TCCAGGAAGG TGAAGAAGGG 900
CGTCCAAAβG ATGACCGCCA CCTCCGTGGC TGTGGCTACC TTCCCGGCTβ CCCGGGCTCC 960
AATGGTTTCC ACAACAACGA CACCTTCCAC TTCCTGAAAT GCTGCAACAC CACCAAATGC 1020
AACGAGGGCC CAATCCTββA GCTTGAAAAT CTGCCGCAβA ATGGCCGCCA GTGTTACAGC 1080
TGCAAGGGβA ACAGCACCCA TGGATGCTCC TCTGAAGAGA CTTTCCTCAT TGACTGCCGA 1140
GGCCCCATGA ATCAATGTCT GGTAGCCACC GGCACTCACG AACCGAAAAA CCAAAGCTAT 1200
ATGGTAAGAG GCTGTGCAAG CGCCTCAATG TGCCAACATC CCCACCTGGG TβACβCCTTC 1260
AGCATGAACC ACATTGATGT CTCCTGCTGT ACTAAAAGTG GCTGTAACCA CCCAGACCTG 1320
GATGTCCAGT ACCGCAGTGG GGCTGCTCCT CAGCCTGGCC CTGCCCATCT CAGCCTCACC 1380
ATCACCCTGC TAATGACTGC CAGACTGTGG GGAGGCACTC TCCTCTGGAC CTAAACCTGA 1440
AATCCCCCTC TCTGCCCTGG CTCGATCCGG GGGACCCCTT TGCCCTTCCC TCGGCTCCCA 1500
GCCCTACAGA CTTGCTGTGT GACCTCAGGC CAGTGTGCCG ACCTCTCTGG GGCTCAGTTT 1560
TCCCAGCTAT GAAAACAGCT ATCTCACAAA GTTGTβTGAA GCAGAAGAGA AAAGCTGβAG 1620
GAAGGCCGTβ GGCAATGβGA GAGCTCTTGT TATTATTAAT ATTGTTGCCG CTGTTGTGTT 1680
GTTGTTATTA ATTAATATTC ATATTATTTA TTTTATACTT ACATAAAGAT TTTGTACCAG 1740
TGG 1743
Seq ID NO: C165 DNA Sequence Nucleic Acid Accession ff: AK027843.1 Coding sequence: 193..1731
11 21 31 41 51
I I I I I
TTGCTTGAGT CATCTTCTGA AGCTTTAAAA ACAATTGATG AATTGGCCTT CAAGATAGAC 60 CTAAATAGCA CATCACATGT GAATATTACA ACTCGGAACT TGGCTCTCAG CGTATCATCC 120 CTGTTACCAG GGACAAATGC AATTTCAAAT TTTAGCATTG GTCTTCCAAG CAATAATGAA 180 TCGTATTTCC AGATGGATTT TGAGAGTGGA CAAGTGGATC CACTGGCATC TGTAATTTTG 240 CCTCCAAACT TACTTGAGAA TTTAAGTCCA GAAGATTCTG TATTAGTTAG AAGAGCACAG 300 TTTACTTTCT TCAACAAAAC TGGACTTTTC CAGGATGTAG GACCCCAAAG AAAAACTTTA 360 GTGAGTTATG TGATGGCGTG CAGTATTGGA AACATTACTA TCCAGAATCT GAAGGATCCT 420 βTTCAAATAA AAATCAAACA TACAAGAACT CAGGAAGTGC ATCATCCCAT CTGTGCCTTC 480
TGGGATCTGA ACAAAAACAA AAGTTTTGGA GGATGGAACA CGTCAGGATG TGTTGCACAC 540
AGAGATTCAG ATGCAAGTGA GACAGTCTGC CTGTGTAACC ACTTCACACA CTTTGGAβTT 600
CTGATGGACC TTCCAAGAAG TGCCTCACAG TTAGATGCAA GAAACACTAA AGTCCTCACT 660
TTCATCAGCT ATATTGGGTG TGGAATATCT GCTATTTTTT CAGCAGCAAC TCTCCTGACA 720
TATGTTGCTT TTGAGAAATT GCGAAGβGAT TATCCCTCCA AAATCTTGAT GAACCTGAGC 780
ACAGCCCTβC TGTTCCTGAA TCTCCTCTTC CTCCTAGATG GCTGβATCAC CTCCTTCAAT 840
GTGGATGGAC TTTGCATTGC TGTTGCAGTC CTGTTGCATT TCTTCCTTCT GGCAACCTTT 900
ACCTGGATGβ GβCTAGAAGC AATTCACATG TACATTGCTC TAGTTAAAGT ATTTAACACT 960
TACATTCGCC CATACATTCT AAAATTCTGC ATCATTGGCT GGGGTTTGCC TGCCTTAGTG 1020
GTGTCAGTTG TTCTAGCGAG CAGAAACAAC AATGAAGTCT ATGGAAAAGA AAGTTATGGG 1080
AAAGAAAAAG GTGATGAATT CTGTTGGATT CAAGATCCAG TCATATTTTA TGTGACCTGT 1140
GCTGGGTATT TTGGAGTCAT GTTTTTTCTG AACATTGCCA TGTTCATTGT GGTAATGGTG 1200
CAGATCTGTG GGAGGAATGG CAAGAβAAGC AACCGGACCC TGAGAGAAGA AGTGTTAAGG 1260
AACCTGCGCA GTGTGGTTAG CTTGACCTTT CTGTTGGGCA TGACATGGGG TTTTGCATTC 1320
TTTGCCTGGG GACCCTTAAA TATCCCCTTC ATGTACCTCT TCTCCATCTT CAATTCATTA 1380
CAAGGCTTAT TTATATTCAT CTTCCACTGT GCTATGAAGG AGAATGTTCA GAAACAGTGG 1440
CGGCGGCATC TCTGCTGTGG TAGATTTCGG TTAGCAGATA ACTCAGATTG GAGTAAGACA 1500
GCTACCAATA TCATCAAGAA AAGTTCTGAT AATCTAββAA AATCTTTGTC TTCAAGCTCC 1560
ATTGβTTCCA ACTCAACCTA TCTTACATCC AAATCTAAAT CCAGCTCTAC CACCTATTTC 1620
AAAAβGAATA GCCACACAGA TAATGTCTCC TATGAGCATT CCTTCAACAA AAGTGGATCA 1680
CTCAGACAGT GCTTCCATGG ACAAGTCCTT GTCAAAACTG GCCCATGCTG ATGGAGATCA 1740
AACATCAATC ATCCCTGTCC ATCAββTCAT TGATAAGGTC AAGGGTTATT GCAATGCTCA 1800
TTCAGACAAC TTCTATAAAA ATATTATCAT GTCAGACACC TTCAGCCACA GCACAAAGTT 1860
TTAATGTCTT TAAGAAAAAG AAATCAATCT GCAGAAATGT GAAGATTTGC AAGCAGTGTA 1920
AACTGCAACT AGTGATGTAA ATGTGCTATT ACCTAGGTAA CTCCATATAT ATAAGGAATG 1980
TATTTTβTTA AGAAGGCTTT TGTGAAATTC AGAATTTTTC TTTTTAATAT ATTTCTTCCA 2040
T6GAAGAGTT GTCATCACTA AAACTTCAGT ACTGAGAGTA ACATGACTCA GTAGCCACAG 2100
AAGCTATGAT TTGTAAAATA TATAATTGAA TCAGAGTAAT CATAATGCAG GGGAβACATT 2160
CAAATTAGAG ACAAGGGAGA AGCAATGCTG AGGAAGACCC TAGATAGAGC TCATTTTACT 2220
CCACCTAATC GTTATATCTG GATATACCCA TTTTCTGCAT CTTCTTTCTC AACAATAAAC 2280
TGTCCTTGCT TTGGAGACTT TAAGACATTT CCTAAAGCAC AAATAAAAGC CTCGTATTTC 2340
CCCATTGAGA GTTTTGTTCC AAGGAATATG AAGTGAGACA TATGGGTGAG TCATAATAAT 2400
CAAAATAATT TATGAAGAGC TGGGTCTGCA ATAGCTAGTC TAAAAACTAC TTGTβTGTCA 2460
GTCCTCTGGT TATAGTATAT AAGAβCCTGA GGAGGTCTGG CAAGATAGAT GβTβTATTAT 2520
TTATGGATCA GGCTGCTGCA TACAAACCTT GCATACTATT ATGCAGCTTA CCTAACTCTC 2580
AGACTATTCT GAGTAATGCT TGCTTGCTAA TGAATGTATA GGAGACCACA TTGTAATTGT 2640
TCTTAGATGA TGGAGTCCAT GCAGTTTCTT AGAAATCGGT CTCAGTGCAT GCTGTGCTTT 2700
TTCACATTTG CTCTGGGTTA TCTGGGAAGT ATCAGGTTCT GGGAGGCAAC AGCATTAAGT 2760
GATAAGAAAA GGAGACATTC TGGCAAAGCC AATCTGCTTA AAGGCAAAGT CCAGAACCTG 2820
GAACCTAGAG GCCTTTCTCT CTCCACβAAA AACAGGTAGT TTGCAGTCTG AGATATGGGA 2880
GAGCTTTTAG GCTACACAGC AACCCAAGGG ACCTCTCACC TTTTGCTGAG CTTCAATCAG 2940
GAAGCTATTT GCCTGGCTCC AGCACATβAT GAGATAATGA GβTAGTGGGT TTTTTATTAC 3000
TGTTCCATTT TGCAACATCC TGCAACACCA TCCTGGGAGA CAAGAGCATT ACCCAGCTTG 3060
GCTTTCACGβ GGGAGGGTTG TATTCAGT 3088
Seq ID NO: C166 DNA Sequence Nucleic Acid Accession ff: NM_000574. Coding sequence: 66..1211
1 11 21 31 41 51 1 1 1 1 | 1 | 1 | 1 1 1 CCGCTGGGCG TAGCTGCβAC TCGGCGGAGT CCCGGCGGCG CGTCCTTGTT CTAACCCGGC 60
GCGCCATGAC CGTCGCGCGG CCGAGCGTGC CCGCGGCβCT GCCCCTCCTC GGGGAGCTGC 120
CCCGGCTGCT GCTGCTGGTG CTGTTGTGCC TGCCGGCCGT GTGGGGTGAC TGTGGCCTTC 180
CCCCAGATGT ACCTAATGCC CAGCCAGCTT TβGAAGGCCG TACAAGTTTT CCCGAGGATA 240
CTGTAATAAC GTACAAATGT GAAβAAAGCT TTGTGAAAAT TCCTGGCGAG AAGGACTCAG 300
TGATCTGCCT TAAGGGCAGT CAATGGTCAG ATATTGAAβA GTTCTGCAAT CGTAGCTGCG 360
AGGTGCCAAC AAGGCTAAAT TCTGCATCCC TCAAACAGCC TTATATCACT CAGAATTATT 420
TTCCAGTCGG TACTGTTGTG GAATATGAGT GCCGTCCAGG TTACAGAAGA GAACCTTCTC 480
TATCACCAAA ACTAACTTGC CTTCAGAATT TAAAATGGTC CACAGCAGTC GAATTTTGTA 540
AAAAGAAATC ATGCCCTAAT CCGGβAβAAA TACGAAATGG TCAGATTGAT GTACCAGβTG 600 βCATATTATT TGGTGCAACC ATCTCCTTCT CATCTAACAC AGGGTACAAA TTATTTGGCT 660
CGACTTCTAG TTTTTGTCTT ATTTCAGGCA βCTCTCTCCA GTGGAGTGAC CCGTTGCCAG 720
AGTGCACAGA AATTTATTGT CCAGCACCAC CACAAATTβA CAATGGAATA ATTCAAGGGG 780
AACGTGACCA TTATGGATAT AGACAGTCTG TAACGTATGC ATGTAATAAA GGATTCACCA 840
TGATTGGAGA GCACTCTATT TATTGTACTG TGAATAATGA TGAAGGAβAG TGGAGTGGCC 900
CACCACCTGA ATGCAGAGGA AAATCTCTAA CTTCCAAGGT CCCACCAACA GTTCAGAAAC 960
CTACCACAGT AAATGTTCCA ACTACAGAAG TCTCACCAAC TTCTCAGAAA ACCACCACAA 1020
AAACCACCAC ACCAAATGCT CAAGCAACAC GGAGTACACC TβTTTCCAGG ACAACCAAGC 1080
ATTTTCATβA AAGAACCCCA AATAAAGGAA GTGGAACCAC TTCAGGTACT ACCCGTCTTC 1140
TATCTGGGCA CACGTGTTTC ACGTTGACAG GTTTGCTTGG GACβCTAGTA ACCATGβGCT 1200
TGCTGACTTA GCCAAAGAAG AGTTAAGAAG AAAATACACA CAAGTATACA GACTGTTCCT 1260
AGTTTCTTAG ACTTATCTGC ATATTGGATA AAATAAATGC AATTGTβCTC TTCATTTAGG 1320
ATβCTTTCAT TGTCTTTAAG ATGTGTTAGG AATβTCAACA GAGCAAGGAG AAAAAAGGCA 1380
GTCCTGGAAT CACATTCTTA GCACACCTAC ACCTCTTGAA AATAGAACAA CTTGCAGAAT 1440
TGAGAGTGAT TCCTTTCCTA AAAGTGTAAβ AAAGCATAGA GATTTGTTCG TATTTAGAAT 1500
GβGATCACGA GGAAAAGAGA AGGAAAβTGA TTTTTTTCCA CAAGATCTGT AATGTTATTT 1560
CCACTTATAA AGGAAATAAA AAATGAAAAA CATTATTTGG ATATCAAAAβ CAAATAAAAA 1620
CCCAATTCAβ TCTCTTCTAA GCAAAATTGC TAAAGAGAGA TCAACCACAT TATAAAGTAA 1680
TCTTTGGCTG TAAGGCATTT TCATCTTTCC TTCGGGTTGG CAAAATATTT TAAAGGTAAA 1740
ACATGCTGβT GAACCAGGGG TGTTGATGGT GATAAGβGAG GAATATAGAA TGAAAGACTβ 1800
AATCTTCCTT TGTTGGACAA ATAGAGTTTG GAAAAAGCCT GTGAAAGGTG TCTTCTTTGA 1860
CTTAATGTCT TTAAAAGTAT CCACAGATAC TACAATATTA ACATAAGAAA AGATTATATA 1920 TTATTTCT6A ATCGAGATGT CCATAGTCAA ATTTGTAAAT CTTATTCTTT TGTAATATTT 1980
ATTTATATTT ATTTATGACA GTGAACATTC TGATTTTACA TGTAAAACAA GAAAAGTTGA 2040
AGAAGATATβ TGAAGAAAAA TGTATTTTTC CTAAATAGAA ATAAATGATC CCATTTTTTG 2100
GT 2102
Seq ID NO: C167 DNA Sequence
Nucleic Acid Accession #: Eos sequence
Coding sequence: 1..2651
GC6ACC 60 CATTGC 120
Figure imgf001305_0001
GAGCTG 180
CCTTCCAACC TCAGCβTCTT CACCTCCTAC CTAGACCTCA GTATGAACAA CATCAGTCAG 240
CTGCTCCCGA ATCCCCTGCC CAGTCTCCGC TTCCTGGAGG AGTTACGTCT TβCβGGAAAC 300
GCTCTGACAT ACATTCCCAA GGGAGCATTC ACTGGCCTTT ACAGTCTTAA AGTTCTTATG 360
CTGCAGAATA ATCAGCTAAG ACACGTACCC ACAβAAGCTC TGCAGAATTT GCβAAGCCTT 420
CAATCCCTGC GTCTGGATGC TAACCACATC AGCTATGTGC CCCCAAGCTG TTTCAGTGGC 480
CTGCATTCCC TGAGGCACCT GTGGCTGGAT GACAATGCGT TAACAGAAAT CCCCGTCCAG 540
GCTTTTAGAA GTTTATCGGC ATTβCAAβCC ATGACCTTGG CCCTGAACAA AATACACCAC 600
ATACCAGACT ATGCCTTTGG AAACCTCTCC AGCTTGGTAG TTCTACATCT CCATAACAAT 660
AGAATCCACT CCCTGGGAAA GAAATGCTTT GATGGGCTCC ACAGCCTAGA GACTTTAGAT 720
TTAAATTACA ATAACCTTGA TGAATTCCCC ACTGCAATTA GGACACTCTC CAACCTTAAA 780
GAACTACATT TCTATGACAA TCCCATCCAA TTTGTTGGGA GATCTGCTTT TCAACATTTA 840
CCTGAACTAA GAACACTGAC TCTGAATGGT GCCTCACAAA TAACTGAATT TCCTGATTTA 900
ACTGGAACTG CAAACCTGGA GAGTCTβACT TTAACTGGAβ CACAGATCTC ATCTCTTCCT 960
CAAACCGTCT GCAATCAGTT ACCTAATCTC CAAGTGCTAG ATCTGTCTTA CAACCTATTA 1020
GAAβATTTAC CCAGTTTTTC AGTCTGGCAA AAGCTTCAGA AAATTGACCT AAGACATAAT 1080
GAAATCTACG AAATTAAAGT TGACACTTTC CAGCA6TTGC TTAGCCTCCG ATCGCTCAAT 1140
TTGβCTTGβA ACAAAATTGC TATTATTCAC CCCAATGCAT TTTCCACTTT GCCATCCCTA 1200
ATAAAGCTGβ ACCTATCGTC CAACCTCCTG TCGTCTTTTC CTATAACTGG GTTACATGβT 1260
TTAACTCACT TAAAATTAAC AGGAAATCAT GCCTTACAGA GCTTGATATC ATCTCAAAAC 1320
TTTCCAGAAC TCAACGTTAT AGAAATGCCT TATGCTTACC AGTGCTβTGC ATTTGGAGTG 1380
TGTGAGAATG CCTATAAGAT TTCTAATCAA TGGAATAAAG GTGACAACAG CAGTATGGAC 1440
GACCTTCATA AGAAAGATGC TGGAATGTTT CAGGCTCAAG ATGAACGTGA CCTTGAAGAT 1500
TTCCTGCTTG ACTTTGAGGA AGACCTGAAA GCCCTTCATT CAGTGCAGTβ TTCACCTTCC 1560
CCAGGCCCCT TCAAACCCTG TGAACACCTG CTTGATGGCT GGCTGATCAG AATTGGAGTG 1620
TGGACCATAG CAGTTCTGGC ACTTACTTGT AATGCTTTGG TGACTTCAAC AGTTTTCAGA 1680
TCCCCTCTGT ACATTTCCCC CATTAAACTG TTAATTGGGG TCATCGCAβC AGTβAACATG 1740
CTCACGGGAG TCTCCAGTGC CGTGCTGGCT GGTGTGGATG CβTTCACTTT TCGCAGCTTT 1800
GCACGACATG GTGCCTGGTG GGAGAATGGG GTTGGTTGCC ATCTCATTGG TTTTTTGTCC 1860
ATTTTTGCTT CAGAATCATC TGTTTTCCTG CTTACTCTGG CAGCCCTGGA GCGTGGGTTC 1920
TCTGTGAAAT ATTCTGCAAA ATTTGAAACG AAAGCTCCAT TTTCTAGCCT GAAAGTAATC 1980
ATTTTGCTCT GTGCCCTGCT GGCCTTGACC ATGGCCGCAG TTCCCCTGCT GGGTGGCAGC 2040
AAGTATGGCG CCTCCCCTCT CTGCCTGCCT TTGCCTTTTG GGGAGCCCAG CACCATGGGC 2100
TACATGGTCG CTCTCATCTT GCTCAATTCC CTTTGCTTCC TCATGATGAC CATTGCCTAC 2160
ACCAAGCTCT ACTβCAATTT βGACAAGGGA GACCTGGAGA ATATTTGGGA CTGCTCTATG 2220
GTAAAACACA TTβCCCTGTT GCTCTTCACC AACTGCATCC TAAACTGCCC TGTGGCTTTC 2280
TTGTCCTTCT CCTCTTTAAT AAACCTTACA TTTATCAGTC CTGAAGTAAT TAAGTTTATC 2340
CTTCTGGTGG TAGTCCCACT TCCTGCATβT CTCAATCCCC TTCTCTACAT CTTGTTCAAT 2400
CCTCACTTTA AGGAGGATCT GGTGAGCCTG AGAAAGCAAA CCTACGTCTG GACAAGATCA 2460
AAACACCCAA GCTTGATGTC AATTAACTCT GATGATGTCG AAAAACAβTC CTGTCACTCA 2520
ACTCAAGCCT TGGTAACCTT TACCAGCTCC AGCATCACTT ATGACCTGCC TCCCAGTTCC 2580
GTGCCATCAC CAGCTTATCC AGTGACTGAG AGCTGCCATC TTTCCTCTGT GGCATTTβTC 2640
CCATGTCTTA A 2651
Seq ID NO: C168 DNA Sequence
Nucleic Acid Accession #: NM_003667.2
Coding sequence: 49..2772
11 21 31 41 51
I I I I I
TGCTGCTCTC CGCCCGCGTC CGGCTCGTGG CCCCCTACTT CGGGCACCAT GβACACCTCC 60 CGGCTCGGTG TGCTCCTGTC CTTGCCTGTG CTGCTGCAGC TGGCGACCGG GGβCAGCTCT 120 CCCAGGTCTG GTGTGTTGCT GAGGGGCTGC CCCACACACT GTCATTGCGA GCCCGACGGC 180 AGGATGTTGC TCAGGGTGGA CTGCTCCGAC CTGβGGCTCT CGGAGCTGCC TTCCAACCTC 240 AGCGTCTTCA CCTCCTACCT AGACCTCAGT ATGAACAAGA TCAGTCAGCT GCTCCCGAAT 300 CCCCTGCCCA GTCTCCGCTT CCTGGAGGAG TTACGTCTTG CGGGAAACGC TCTGACATAC 360 ATTCCCAAGG GAGCATTCAC TGGCCTTTAC AGTCTTAAAG TTCTTATGCT GCAGAATAAT 420 CAGCTAAGAC ACGTACCCAC AGAAGCTCTG CAGAATTTGC βAAGCCTTCA ATCCCTGCGT 480 CTGGATGCTA ACCACATCAG CTATGTGCCC CCAAGCTGTT TCAGT6GCCT GCATTCCCTG 540 AGGCACCTGT GGCTGGATGA CAATGCGTTA ACAGAAATCC CCGTCCAGGC TTTTAGAAGT 600 TTATCGGCAT TGCAAGCCAT GACCTTββCC CTGAACAAAA TACACCACAT ACCAGACTAT 660 GCCTTTGβAA ACCTCTCCAβ CTTGGTAGTT CTACATCTCC ATAACAATAG AATCCACTCC 720 CTGGGAAAGA AATGCTTT6A TGGGCTCCAC AGCCTAGAGA CTTTAGATTT AAATTACAAT 780 AACCTTGATG AATTCCCCAC TGCAATTAGG ACACTCTCCA ACCTTAAAGA ACTAGGATTT 840 CATAGCAACA ATATCAGGTC GATACCTGAβ AAAGCATTTG TAGGCAACCC TTCTCTTATT 900 ACAATACATT TCTATGACAA TCCCATCCAA TTTGTTGGGA GATCTGCTTT TCAACATTTA 960 CCTGAACTAA GAACACTGAC TCTGAATG6T GCCTCACAAA TAACTGAATT TCCTGATTTA 1020 ACTGGAACTG CAAACCTGGA GAGTCTGACT TTAACTGGAβ CACAGATCTC ATCTCTTCCT 1080 CAAACCGTCT GCAATCAGTT ACCTAATCTC CAAGTGCTAG ATCTGTCTTA CAACCTATTA 1140 GAAGATTTAC CCAGTTTTTC AGTCTGCCAA AAGCTTCAGA AAATTGACCT AAGACATAAT 1200 GAAATCTACG AAATTAAAGT TGACACTTTC CAGCAGTTGC TTAGCCTCCG ATCGCTGAAT 1260 TTGGCTTGGA ACAAAATTGC TATTATTCAC CCCAATGCAT TTTCCACTTT GCCATCCCTA 1320
ATAAAGCTGG ACCTATCGTC CAACCTCCTG TCGTCTTTTC CTATAACTGG GTTACATGGT 1380
TTAACTCACT TAAAATTAAC AGGAAATCAT GCCTTACAGA GCTTGATATC ATCTGAAAAC 1440
TTTCCAGAAC TCAAGGTTAT AGAAATGCCT TATGCTTACC AGTGCTGTGC ATTTGGAGTG 1500
TGTGAGAATG CCTATAAGAT TTCTAATCAA TGβAATAAAG GTβACAACAG CAGTATGGAC 1560
GACCTTCATA AGAAAGATβC TGGAATGTTT CAGGCTCAAG ATGAACGTβA CCTTGAAGAT 1620
TTCCTGCTTG ACTTTβAβGA AGACCTGAAA GCCCTTCATT CAGTGCAGTG TTCACCTTCC 1680
CCAGβCCCCT TCAAACCCTG TGAACACCTG CTTGATGGCT GGCTGATCAG AATTGGAGTβ 1740
TGGACCATAG CAGTTCTGGC ACTTACTTGT AATGCTTTGG TGACTTCAAC AGTTTTCAGA 1800
TCCCCTCTGT ACATTTCCCC CATTAAACTG TTAATTGGGG TCATCGCAGC AGTGAACATG 1860
CTCACGGGAG TCTCCAβTβC CGTGCTGGCT GGTGTGGATG CGTTCACTTT TGGCAGCTTT 1920
GCACGACATG βTGCCTGGTG GβAGAATGGG GTTGGTTGCC ATCTCATTGG TTTTTTGTCC 1980
ATTTTTGCTT CAGAATCATC TGTTTTCCTβ CTTACTCTGG CAGCCCTGGA GCGTGGGTTC 2040
TCTGTGAAAT ATTCTGCAAA ATTTβAAACG AAAGCTCCAT TTTCTAGCCT GAAAGTAATC 2100
ATTTTβCTCT βTβCCCTβCT GGCCTTGACC ATGGCCGCAG TTCCCCTGCT GGGTGGCAGC 2160
AAGTATGGCG CCTCCCCTCT CTGCCTGCCT TTGCCTTTTG GGGAGCCCAG CACCATGβGC 2220
TACATGGTCG CTCTCATCTT GCTCAATTCC CTTTGCTTCC TCATGATGAC CATTGCCTAC 2280
ACCAAβCTCT ACTβCAATTT GGACAAββGA GACCTGGAGA ATATTTGGGA CTGCTCTATG 2340
GTAAAACACA TTGCCCTGTT GCTCTTCACC AACTGCATCC TAAACTGCCC TGTGGCTTTC 2400
TTGTCCTTCT CCTCTTTAAT AAACCTTACA TTTATCAGTC CTGAAGTAAT TAAGTTTATC 2460
CTTCTGGTGG TAGTCCCACT TCCTCCATGT CTCAATCCCC TTCTCTACAT CTTGTTCAAT 2520
CCTCACTTTA AGGAGGATCT GGTGAβCCTG AGAAAGCAAA CCTACGTCTG GACAAGATCA 2580
AAACACCCAA βCTTβATβTC AATTAACTCT βATβATβTCG AAAAACAGTC CTGTGACTCA 2640
ACTCAAGCCT TGGTAACCTT TACCAGCTCC AGCATCACTT ATGACCTGCC TCCCAGTTCC 2700
GTGCCATCAC CAGCTTATCC AGTGACTGAG AGCTGCCATC TTTCCTCTGT GGCATTTCTC 2760
CCATGTCTCT AATTAATATG TGAAGGAAAA TGTTTTCAAA GGTTGAGAAC CTGAAAATGT 2820
GAGATTGAGT ATATCAGAGC AGTAATTAAT AAGAAGAGCT GAGGTGAAAC TCGGTTTAAA 2880
Seq ID NO: C169 DNA Sequence Nucleic Acid Accession ft: NM_003506.1 Coding sequence: 259..2379
1 11 21 31 41 51
I I I I I I
GCAGCTCCAβ TCCC6GACGC AACCCCGGAG CCGTCTCAββ TCCCTGGGGG GAACGGTGGG 60
TTAGACGGββ ACGGGAAGGβ ACAGCGβCCT TCβACCβCCC CCCβAβTAAT TGACCCAGGA 120
CTCATTTTCA GGAAAGCCTG AAAATGAGTA AAATAβTβAA ATGAGGAATT TGAACATTTT 180
ATCTTTGβAT βββGATCTTC TGAGGATGCA AAGA6TGATT CATCCAAGCC ATGTGGTAAA 240
ATCAGβAATT TCAAβAAAAT ββAβATβTTT ACATTTTTGT TGACGTβTAT TTTTCTACCC 300
CTCCTAAGAG GGCACAGTCT CTTCACCTGT GAACCAATTA CTGTTCCCAG ATGTATGAAA 360
ATββCCTACA ACATCACCTT TTTCCCTAAT CTβATGGGTC ATTATGACCA GAGTATTGCC 420
GCGGTGGAAA TGGAGCATTT TCTTCCTCTC GCAAATCTGG AATGTTCACC AAACATTGAA 480
ACTTTCCTCT GCAAACCATT TGTACCAACC TGCATAGAAC AAATTCATGT GGTTCCACCT 540
TGTCGTAAAC TTTCTGAGAA AGTATATTCT GATTGCAAAA AATTAATTGA CACTTTTGGG 600
ATCCGATGGC CTGAGGAGCT TGAATGTGAC AGATTACAAT ACTGTGATGA GACTGTTCCT 660
GTAACTTTTG ATCCACACAC AGAATTTCTT GGTCCTCAGA AGAAAACAGA ACAAGTCCAA 720
AGAGACATTG GATTTTGGTG TCCAAGGCAT CTTAAGACTT CTGGGGGACA AGGATATAAG 780
TTTCTGΘ3AA TTGACCAGTG TGCGCCTCCA TGCCCCAACA TGTATTTTAA AAGTβATβAβ 840
CTAβAβTTTG CAAAAAGTTT TATTGGAACA GTTTCAATAT TTTGTCTTTG TβCAACTCTβ 900
TTCACATTCC TTACTTTTTT AATTGATGTT AGAAGATTCA GATACCCAGA GAβACCAATT 960
ATATATTACT CTGTCTGTTA CAGCATTGTA TCTCTTATGT ACTTCATTGG ATTTTTGCTG 1020
GGCGATAGCA CAGCCTGCAA TAAββCACAT GAGAAGCTAC AACTTCGTGA CACTGTTGTC 1080
CTAGGCTCTC AAAATAAGβC TTGCACCGTT TTβTTCATGC TTTTGTATTT TTTCACAATG 1140
GCTGGCACTG TGTGGTβGGT GATTCTTACC ATTACTTGGT TCTTAGCTGC AGGAAGAAAA 1200
TGGAGTTGTG AAGCCATCGA GCAAAAAGCA GTGTGGTTTC ATβCTGTTGC ATGGGGAACA 1260
CCAG6TTTCC TGACTGTTAT GCTTCTTGCT CTGAACAAAG TTGAAGGAGA CAACATTAGT 1320
GGAGTTTGCT TTGTTGGCCT TTATGACCTG GATGCTTCTC GCTACTTTGT ACTCTTGCCA 1380
CTGTGCCTTT GTGTGTTTGT TGGβCTCTCT CTTCTTTTAG CTGGCATTAT TTCCTTAAAT 1440
CATGTTCGAC AAGTCATACA ACATGATGGC CβGAACCAAG AAAAACTAAA GAAATTTATG 1500
ATTCGAATTβ GAGTCTTCAG CGGCTTGTAT CTTGTGCCAT TAGTGACACT TCTCGGATGT 1560
TACGTCTATG AGCAAGTβAA CAGGATTACC TGGGAGATAA CTTGGGTCTC TGATCATTGT 1620
CGTCAGTACC ATATCCCATG TCCTTATCAβ GCAAAAGCAA AAGCTCGACC AGAATTGGCT 1680
TTATTTATGA TAAAATACCT GATGACATTA ATTGTTGβCA TCTCTGCTGT CTTCTGGGTT 1740
GGAAGCAAAA AGACATGCAC AGAATGGβCT GGGTTTTTTA AACGAAATCG CAAGAGAGAT 1800
CCAATCAGTG AAAGTCGAAG AGTACTACAG GAATCATGTG AGTTTTTCTT AAAGCACAAT 1860
TCTAAAGTTA AACACAAAAA GAAGCACTAT AAACCAAGTT CACACAAGCT GAAGGTCATT 1920
TCCAAATCCA TGGGAACCAβ CACAGGAGCT ACAGCAAATC ATGGCACTTC TGCAGTAGCA 1980
ATTACTAGCC ATGATTACCT AGGACAAGAA ACTTTGACAG AAATCCAAAC CTCACCAGAA 2040
ACATCAATGA GAGAGGTGAA AGCGGACGGA GCTAGCACCC CCAGGTTAAG AGAACAGGAC 2100
TGTGGTGAAC CTGCCTCGCC AGCAGCATCC ATCTCCAGAC TCTCTGGββA ACAGGTCGAC 2160
GGGAAGGβCC AGGCAGGCAG TGTATCTGAA AGTGCGCGGA GTGAAGβAAβ βATTAGTCCA 2220
AAGAGTGATA TTACTGACAC TββCCTCCCA CA6A6CAACA ATTTGCAGGT CCCCAGTTCT 2280
TCAGAACCAA GCAGCCTCAA AGGTTCCACA TCTCTGCTTG TTCACCCAGT TTCAGGAGTG 2340
AGAAAAGAGC AGGGAGGTGG TTGTCATTCA GATACTTGAA GAACATTTTC TCTCGTTACT 2400
CAGAAGCAAA TTTGTGTTAC ACTG6AAGTG ACCTATGCAC TGTTTTGTAA GAATCACTGT 2460
TACGTTCTTC TTTTGCACTT AAAGTTGCAT TGCCTACTGT TATACTGGAA AAAATAGAGT 2520
TCAAGAATAA TATGACTCAT TTCACACAAA GGTTAATβAC AACAATATAC CTGAAAACAG 2580
AAATβTGCAG GTTAATAATA TTTTTTTAAT AβTβTGGβAG GACAGAGTTA GAGGAATCTT 2640
CCTTTTCTAT TTATGAAGAT TCTACTCTTG GTAAGAGTAT TTTAAGATGT ACTATGCTAT 2700
TTTACCTTTT TGATATAAAA TCAAGATATT TCTTTGCTGA AGTATTTAAA TCTTATCCTT 2760
GTATCTTTTT ATACATATTT GAAAATAAGC TTATATGTAT TTGAACTTTT TT6AAATCCT 2820
ATTCAA6TAT TTTTATCATβ CTATTGTGAT ATTTTAGCAC TTTGGTAGCT TTTACACTGA 2880
ATTTCTAAGA AAATTGTAAA ATAGTCTTCT TTTATACTGT AAAAAAAGAT ATACCAAAAA 2940
GTCTTATAAT AGGAATTTAA CTTTAAAAAG CCACTTATTG ATACCTTACC ATCTAAAATG 3000 TGTGATTTTT ATAGTCTCGT TTTAGGAATT TCACAGATCT AAATTATGTA ACTβAAATAA 3060
GGTGCTTACT CAAAGAβTβT CCACTATTGA TTGTATTATG CTGCTCACTG ATCCTTCTGC 3120
ATATTTAAAA TAAAATGTCC TAAAGGGTTA GTAGACAAAA TGTTAGTCTT TTGTATATTA 3180
GGCCAAGTGC AATTGACTTC CCTTTTTTAA TGTTTCATGA CCACCCATTG ATTGTATTAT 3240
AACCACTTAC AGTTGCTTAT ATTTTTTGTT TTAACTTTTG TTTCTTAACA TTTAGAATAT 3300
TACATTTTGT ATTATACAGT ACCTTTCTCA GACATTTTGT AG 3342
Seq ID NO: C170 DNA Sequence Nucleic Acid Accession ff: NM_000582 Coding sequence: 88...990
1 11 21 31 41 51 1 1 | 1 I 1 | 1 | 1 | 1 GCAGAGCACA GCATCGTCGG GACCAGACTC GTCTCAGGCC AGTTGCAGCC TTCTCAGCCA 60
AACGCCGACC AAGGAAAACT CACTACCATG AGAATTGCAG TGATTTGCTT TTGCCTCCTA 120
GGCATCACCT GTGCCATACC AGTTAAACAG GCTGATTCTG GAAGTTCTGA GGAAAAGCAG 180
CTTTACAACA AATACCCAGA TGCTGTGGCC ACATGGCTAA ACCCTGACCC ATCTCAGAAG 240
CAGAATCTCC TAGCCCCACA GACCCTTCCA AGTAAGTCCA ACGAAAGCCA TGACCACATG 300
GATGATATGG ATGATGAAGA TGATGATGAC CATGTGGACA GCCAGGACTC CATTGACTCG 360
AACGACTCTG ATGATGTAGA TGACACTGAT GATTCTCACC AGTCTGATGA βTCTCACCAT 420
TCTGATβAAT CTGATGAACT GGTCACTGAT TTTCCCACGβ ACCTGCCAGC AACCGAAGTT 480
TTCACTCCAG TTGTCCCCAC AGTAGACACA TATGATGGCC GAGGTGATAG TGTGGTTTAT 540
GGACTGAGGT CAAAATCTAA GAAGTTTCGC AβACCTβACA TCCAGTACCC TGATGCTACA 600
GACGAGGACA TCACCTCACA CATGGAAAGC GA6GAGTTGA ATGGTGCATA CAAGGCCATC 660
CCCGTTGCCC AGβACCTGAA CGCGCCTTCT GATTGGGACA GCCGTGGGAA GGACAGTTAT 720
GAAACGAGTC AGCTGGATGA CCAGAGTCCT GAAACCCACA GCCACAAGCA GTCCAGATTA 780
TATAAGCGβA AAGCCAATGA TGAGAGCAAT GAGCATTCCG ATGTGATTGA TAGTCAGGAA 840
CTTTCCAAAG TCAGCCGTGA ATTCCACAGC CATGAATTTC ACAGCCATGA AGATATGCTG 900
GTTGTAGACC CCAAAAGTAA GGAAGAAGAT AAACACCTGA AATTTCGTAT TTCTCATGAA 960
TTAGATAGTG CATCTTCTGA GβTCAATTAA AAGGAGAAAA AATACAATTT CTCACTTTGC 1020
ATTTAGTCAA AAGAAAAAAT GCTTTATAGC AAAATGAAAG AGAACATGAA ATGCTTCTTT 1080
CTCAGTTTAT TGGTTGAATβ TGTATCTATT TGAGTCTββA AATAACTAAT GTGTTTGATA 1140
ATTAGTTTAG TTTGTGGCTT CATGβAAACT CCCTGTAAAC TAAAAGCTTC AGGGTTATGT 1200
CTATGTTCAT TCTATAGAAG AAATGCAAAC TATCACTGTA TTTTAATATT TGTTATTCTC 1260
TCATGAATAG AAATTTATGT AGAAGCAAAC AAAATACTTT TACCCACTTA AAAAGAGAAT 1320
ATAACATTTT ATGTCACTAT AATCTTTTGT TTTTTAACTT AGTGTATATT TTGTTGTGAT 1380
TATCTTTTTβ TGGTGTGAAT AAATCTTTTA TCTTGAATGT AATAAGAATT TGGTGGTGTC 1440
AATTGCTTAT TTGTTTTCCC ACGGTTGTCC AGCAATTAAT AAAACATAAC CTTTTTTACT 1500
GCCTAAAAAA AAAAAAAAAA AAAA 1524
Seq ID NO: C171 DNA Sequence Nucleic Acid Accession ft: NM_002821 Coding sequence: 150..3362 1 11 21 31 41 51
AACTCCCGCC TCGGGACGCC TCGGGGTCGG GCTCCGGCTβ CGGCTGCTGC TGCGGCGCCC 60
GCGCTCCGGT GCGTCCGCCT CCTGTGCCCG CCGCβGAβCA GTCTGCGGCC CGCCGTGCGC 120
CCTCAGCTCC TTTTCCTGAG CCCGCCGCGA TGβGAGCTGC GCGGGGATCC CCGGCCAGAC 180
CCCGCCGGTT GCCTCTGCTC AGCGTCCTGC TGCTβCCGCT GCTGGβCGGT ACCCAGACAG 240
CCATTGTCTT CATCAAGCAG CCGTCCTCCC AGGATGCACT GCAGGGGCGC CGGGCGCTGC 300
TTCGCTGTGA GGTTGAGGCT CCGGGCCCGG TACATGTGTA CTGGCTGCTC GATGGGGCCC 360
CTGTCCAGβA CACGGAGCGG CGTTTCGCCC AGGGCAGCAG CCTβAβCTTT GCAGCTGTGG 420
ACCGβCTGCA GGACTCTGGC ACCTTCCAGT GTGTGGCTCG GGATGATGTC ACTGGAGAAG 480
AAGCCCGCAG TGCCAACGCC TCCTTCAACA TCAAATGGAT TGAGGCAGGT CCTGTGGTCC 540
TCAAGCATCC AGCCTCGGAA GCTGAGATCC AGCCACAGAC CCAGGTCACA CTTCGTTGCC 600
ACATTGATGG GCACCCTCGG CCCACCTACC AATGGTTCCG AGATGGGACC CCCCTTTCTG 660
ATGGTCAGAG CAACCACACA GTCAGCAβCA AGGAGCGGAA CCTβACGCTC CGGCCAGCTG 720
GTCCTGAGCA TAGTGGGCTG TATTCCTGCT GCGCCCACAG TGCTTTTGGC CAGGCTTGCA 780
GCAGCCAGAA CTTCACCTTG AGCATTGCTG ATGAAAGCTT TGCCAGGGTβ GTGCTGGCAC 840
CCCAGGACGT GGTAGTAGCG AGGTATGAGG AGGCCATGTT CCATTGCCAG TTCTCAGCCC 900
AGCCACCCCC GAGCCTGCAG TGGCTCTTTG AGGATGAGAC TCCCATCACT AACCGCAGTC 960
GCCCCCCACA CCTCCGCAGA GCCACAGTGT TTGCCAACGG GTCTCTβCTG CTGACCCAGG 1020
TCCGGCCACG CAATGCAGGG ATCTACCGCT GCATTGGCCA GGGGCAGAGG GGCCCACCCA 1080
TCATCCTGGA AGCCACACTT CACCTAGCAG AGATTGAAGA CATGCCGCTA TTTGAGCCAC 1140
GGGTGTTTAC AGCTGGCAGC GAGGAGCGTG TGACCTGGCT TCCCCCCAAG GGTCTGCCAG 1200
AGCCCAGCGT GTGGTGGGAG CACGCGGGAG TCCGGCTGCC CACCCATGGC AGGGTCTACC 1260
AGAAGGGCCA CGAGCTGGTG TTGGCGAATA TTGCTGAAAG TGATGCTGGT βTCTACACCT 1320
GCCACGCGGC CAACCTGGCT GβTCAGCGGA GACAGGATGT CAACATCACT GTGGCCACTG 1380
TGCCCTCCTG GCTGAAGAAG CCCCAAGACA GCCAGCTGGA GGAGGGCAAA CCCGGCTACT 1440
TGGATTGCCT GACCCAGGCC ACACCAAAAC CTACAGTTGT CTGGTACAGA AACCAGATGC 1500
TCATCTCAGA GGACTCACGG TTCGAGGTCT TCAAGAATGG GACCTTGCβC ATCAACAGCG 1560
TGGAG6TGTA TGATGβGACA TCβTACCGTT GTATGAGCAG CACCCCAGCC GGCAGCATCG 1620
AGGCβCAAGC CCGTGTCCAA GTGCTGGAAA AGCTCAAGTT CACACCACCA CCCCAGCCAC 1680
AGCAGTGCAT GGAGTTTGAC AAGβAGGCCA CGGTGCCCTG TTCAGCCACA GGCCGAGAGA 1740
AGCCCACTAT TAAGTGGGAA CGGGCAGATG GβAGCAGCCT CCCAGAβTGG GTGACAGACA 1800
ACGCTGGGAC CCTGCATTTT GCCCGGGTGA CTCGAGATGA CGCTGGCAAC TACACTTGCA 1860
TTGCCTCCAA CGGGCCGCAG GGCCAGATTC GTGCCCATGT CCAGCTCACT GTGGCAβTTT 1920
TTATCACCTT CAAAGTβGAA CCAGAGCGTA CGACTGTGTA CCAGGGCCAC ACAGCCCTAC 1980
TGCAGTGCGA GGCCCAGGGβ GACCCCAAGC CGCTGATTCA GTGGAAAGGC AAGβACCGCA 2040
TCCTGGACCC CACCAAGCTG GGACCCAGGA TGCACATCTT CCAGAATGGC TCCCTGGTGA 2100
TCCATCACGT GGCCCCTGAG GACTCAGGCC GCTACACCTG CATTGCAGGC AACAGCTGCA 2160
ACATCAAGCA CACGGAGGCC CCCCTCTATG TCGTGGACAA GCCTβTβCCβ GAGGAGTCGG 2220
AGGGCCCTGG CAGCCCTCCC CCCTACAAGA TGATCCAGAC CATTGβGTTG TCGGTGGGTG 2280
CCGCTGTGGC CTACATCATT GCCGTGCTββ GCCTCATGTT CTACTGCAAG AAGCβCTβCA 2340 AAGCCAAGCβ GCTGCAGAAG CAGCCCGAGG GCGAGGAGCC AGAGATGGAA TGCCTCAACG 2400
GAGGGCCTTT GCAGAACGGG CAGCCCTCAG CAGAGATCCA AβAAGAAGTG GCCTTGACCA 2460
GCTTGGGCTC CGGCCCCGCG GCCACCAACA AACGCCACAG CACAACTGAT AAGATGCACT 2520
TCCCACGGTC TAGCCTGCAG CCCATCACCA CGCTGGGGAA GAGTGAβTTT GGGGAGGTGT 2580
TCCTGGCAAA GGCTCAGGGC TTGGAGGAGG GAGTGGCAGA GACCCTGGTA CTTGTGAAGA 2640
GCCTGCAGAC GAAGGATGAβ CAGCAGCAGC TGGACTTCCG GAGGGAGTTG GAGATGTTTG 2700
GGAAGCTGAA CCACGCCAAC GTββTGCGGC TCCTGGGGCT GTGCCG6GAG GCTGAGCCCC 2760
ACTACATGGT GCTGβAATAT GTGGATCTGG GAGACCTCAA GCAGTTCCTG AGGATTTCCA 2820
AGAGCAAGGA TGAAAAATTG AAGTCACAGC CCCTCAGCAC CAAGCAGAAG GTGGCCCTAT 2880
GCACCCAGGT AGCCCTGGGC ATGGAGCACC TGTCCAACAA CCGCTTTGTG CATAAGGACT 2940
TGGCTGCGCG TAACTGCCTG GTCAGTGCCC AGAGACAAGT GAAGGTGTCT GCCCTGββCC 3000
TCAGCAAGGA TGTβTACAAC AGTGAGTACT ACCACTTCCG CCAGGCCTGG GTGCCGCTGC 3060
GCTGGATGTC CCCCGAGGCC ATCCTGGAGG GTGACTTCTC TACCAAGTCT GATGTCTGGG 3120
CCTTCGGTGT GCTGATGTGG GAAGTGTTTA CACATGGAGA GATGCCCCAT GβTGββCAGG 3180
CAGATGATGA AβTACTββCA GATTTGCAGG CTGGGAAGGC TAGACTTCCT CAGCCCβAββ 3240
GCTGCCCTTC CAAACTCTAT CGβCTGATGC AGCGCTGCTG GGCCCTCAGC CCCAAGGACC 3300
GGCCCTCCTT CAGTCAGATT GCCAGCGCCC TGGGAGACAG CACCGTGGAC AGCAAGCCGT 3360
GAGGAGGGAG CCCGCTCAGβ ATGGCCTGGG CAGGGGAGGA CATCTCTAGA GβGAAGCTCA 3420
CAGCATCATC GGCAAGATCC CTGTCCTCCT G6GCCCTGAG GTGCCCTAGT GCAACAGGCA 3480
TTGCTGAGβT CTGAGCAβGG CCTGGCCTTT CCTCCTCTTC CTCACCCTCA TCCTTTGGGA 3540
GGCTGACTTG GACCCAAACT GGGCGACTAG GGCTTTGAGC TGGGCAGTTT CCCCTGCCAC 3600
CTCTTCCTCT ATCAGGGACA GTGTGGGTGC CACAGGTAAC CCCAATTTCT G6CCTTCAAC 3660
TTCTCCCCTT GACCGGβTCC AACTCTCCCA CTCATCTGCC AACTTTGCCT βββGAGGGCT 3720
AGGCTTGGGA TGAGCTGGGT TTGTGGGGAG TTCCTTAATA TTCTCAAβTT CTGβGCACAC 3780
AGGGTTAATG AGTCTCTTGC CCACTGGTCC ACTTGGGGGT CTAβACCAGG ATTATAGAGG 3840
ACACAGCAAG TGAGTCCTCC CCACTCTGGG CTTGTGCACA CTGACCCAGA CCCACGTCTT 3900
CCCCACCCTT CTCTCCTTTC CTCATCCTAA GTGCCTGGCA GATGAAGGAG TTTTCAGGAG 3960
CTTTTGACAC TATATAAACC GCCCTTTTTG TATGCACCAC GGGCGGCTTT TATATCTAAT 4020
TGCAGCGTGG GGTGGGTGGβ CATGGGAGGT AGGGGTGGGC CCTGGAGATG AGGAGGGTGG 4080
GCCATCCTTA CCCCACACTT TTATTGTTGT CGTTTTTTGT TTGTTTTGTT TTTTTCTTTT 4140
TGTTTTTGTT TTTACACTCG CTGCTCTCAA TAAATAAGCC TTTTTTA 4187
Seq ID NO: C172 DNA Sequence
Nucleic Acid Accession ft: NM_002309.2
Coding sequence: 65.-673
1 11 21 31 41 51
I I I I I I
ATGAACCTCT GAAAACTGCC βGCATCTGAG GTTTCCTCCA AGGCCCTCTG AAGTCCAGCC 60 CATAATGAAG GTCTTGGCCG CAGβAGTTGT GCCCCTGCTG TTGGTTCTGC ACTGGAAACA 120 TGGGGCGGGG AGCCCCCTCC CCATCACCCC TGTCAACGCC ACCTGTGCCA TACGCCACCC 180 ATGTCACAAC AACCTCATGA ACCAGATCAG GAGCCAACTG GCACAGCTCA ATGGCAGTGC 240 CAATGCCCTC TTTATTCTGT ATTACACAGC CCAGGGGGAG CCGTTCCCCA ACAACCTGGA 300 CAAGCTATGT GGCCCCAACG TGACGGACTT CCCGCCCTTC CACGCCAACG GCACGGAGAA 360 GGCCAAβCTG GTGGAGCTGT ACCGCATAGT CCTCTACCTT GGCACCTCCC TGβGCAACAT 420 CACCCGGGAC CAGAAGATCC TCAACCCCAG TGCCCTCAβC CTCCACAβCA AβCTCAACβC 480 CACCGCCGAC ATCCTGCGAG GCCTCCTTAG CAACβTβCTβ TβCCβCCTGT GCAGCAAGTA 540 CCACGTGGGC CATGTGGACG TGACCTACGG CCCTGACACC TCGGGTAAGG ATGTCTTCCA 600 GAAGAAGAAG CTGGGCTGTC AACTCCTGGG GAAGTATAAG CAGATCATCG CCGTGTTGGC 660 CCAGGCCTTC TAGCAGGAGG TCTTGAAGTG TGCTGTGAAC CGAGGGATCT CAGGAGTTGG 720 GTCCAGATGT GGGGGCCTGT CCAAGGGTGG CTGGGGCCCA GGGCATCGCT AAACCCAAAT 780 GGGGGCTGCT GGCAGACCCC GAGGGTGCCT GGCCAGTCCA CTCCACTCTG GGCTGGGCTG 840 TGATGAAGCT GAGCAGAGTG GAAACTTCCA TAGGGAGGGA GCTAGAAβAA GGTGCCCCTT 900 CCTCTGGGAG ATTGTGGACT GGGGAGCGTG GGCTGGACTT CTGCCTCTAC TTGTCCCTTT 960 GGCCCCTTCC TCACTTTGTG CAGTGAACAA ACTACACAAG TCATCTACAA GAGCCCTβAC 1020 CACAGGGTGA GACAGCAGGG CCCAGGGGAG TGβACCAβCC CCCAGCAAAT TATCACCATC 1080 TGTGCCTTTG CTGCCCCTTA GGTTGGGACT TAGGTGGGCC AGAGGGGCTA GGATCCCAAA 1140 GβACTCCTTG TCCCCTAGAA GTTTGATGAG TGGAAGATAG AGAGGGGCCT CTGGGATGGA 1200 AGβCTCTCTT CTTTTGAGGA TGATCAGAGA ACTTGGGCAT AGGAACAATC TGGCAβAAβT 1260 TTCCAGAAGG AGGTCACTTG GCATTCAGGC TCTTβGGGAG GCAGAGAAGC CACCTTCAGG 1320 CCTGGGAAGG AAGACACTGG GAGGAGGAGA GGCCTGGAAA GCTTTGGTAG GTTCTTCGTT 1380 CTCTTCCCCG TGATCTTCCC TGCAGCCTGG GATGGCCAGG GTCTGATGGC TGGACCTGCA 1440 GCAGGGGTTT GTGGAGGTGG GTAGGGCAGG GGCAGGTTGC TAAGTCAβGT GCAGAGGTTC 1500 TGAGGGACCC AGGCTCTTCC TCTGGGTAAA GGTCTGTAAG AAGGGGCTGG GβTAβCTCAG 1560 AβTAβCAβCT CACATCTGAG GCCCTGGGAG GTCTTGTGAβ GTCACACAGA GGTACTTGAβ 1620 GGGGACTCGA GGCCGTCTCT GGTCCCCAGG GCAAGGβAAC AGCAGAACTT AGGGTCAββG 1680 TCTCAGGGAA CCCTGAGCTC CAAGCGTGCT GTGCGTCTGA CCTGGCATGA TTTCTATTTA 1740 TTATGATATC CTATTTATAT TAACTTATTG GTGCTTTCAG TGGCCAAGTT AATTCCCCTT 1800 TCCCTGGTCC CTACTCAACA AAATATGATG ATGGCTCCCG ACACAAGCGC CAGGGCCAGG 1860 GCTTAGCAGG GCCTGGTCTG GAAGTCGACA ATGTTACAAG TGGAATAAGC TTACGGGTGA 1920 AGCTCAGAGA AGGGTCGGAT CTGAGAGAAT GGGGAGGCCT GAGTGGGAGT GGGGGGCCTT 1980 GCTGCAGCCC CATCCCCTAC TGTGACTTGC TTTAGCβTGT CAGGGTCCAG GCTGCAGGGG 2040 CTGGGCCAAT TTGTGGAGAG GCCGGGTGCC TTTCTGTCTT GCTTCCAGGG GGCTGGTTCA 2100 CACTGTTCTT GGβCGCCCCA GCATTGTGTT GTGAGGCGCA CTGTTCCTGG CAGATATTGT 2160 GCCCCCTGGA GCAGTGGGCA AGACAGTCCT TGTGGCCCAC CCTGTCCTTG TTTCTGTGTC 2220 CCCATGCTGC CTCTGAAATA GCGCCCTGβA ACAACCCTGC CCCTGCACCC AGCATGCTCC 2280 GACACAβCAG GGAAGCTCCT CCTGTGGCCC GGACACCCAT AGACGGTGCG GGGGGCCTGG 2340 CTGGGCCAGA CCCCAGGAAG GTGGGGTAGA CTGGGGGGAT CAGCT6CCCA TTGCTCCCAA 2400 GAGGAGGAGA GGGAGGCTGC AGACGCCTGG GACTCAGACC AGGAAGCTGT GGGCCCTCCT 2460 GCTCCACCCC CATCCCACTC CCACCCATβT CTGGGCTCCC AGGCAGGGAA . CCCGATCTCT 2520 TCCTTTGTGC TGβGGCCAGG CGAGTGGAGA AACGCCCTCC AGTCTGAGAG I CAGGGGAGGG 2580 AAGGAGGCAG CAGAGTTGGG GCAGCTGCTC AGAGCAGTGT TCTGGCTTCT ' TCTCAAACCC 2640 TGAGCGGGCT GCCGGCCTCC AAGTTCCTCC GACAAGATGA TGGTACTAAT 1 TATGGTACTT 2700 TTCACTCACT TTGCACCTTT CCCTGTCGCT CTCTAAGCAC TTTACCTGGA . TGGCGCGTGG 2760 GCAGTGTGCA GGCAGGTCCT GAGGCCTGGG GTTGGGGTGG AGGGTGCGGC CCGGAGTTGT 2820
CCATCTGTCC ATCCCAACAG CAAGACβAGG ATGTGGCTGT TGAGATGTGG βCCACACTCA 2880
CCCTTGTCCA GGATGCAGββ ACTGCCTTCT CCTTCCTGCT TCATCCGGCT TAβCTTβGGG 2940
CTGGCTGCAT TCCCCCAGGA TGGGCTTCGA GAAAGACAAA CTTGTCTGGA AACCAGAGTT 3000
GCTGATTCCA CCCGGGGGGC CCGGCTGACT CβCCCATCAC CTCATCTCCC TGTGGACTTC 3060
GGAGCTCTGT GCCAGGCCCA CCTTGCGGCC CTGGCTCTGA βTCβCTCTcc CACCCAGCCT 3120
GGACTTGβCC CCATGGβACC CATCCTCAGT GCTCCCTCCA βATCCCCTCC GGCAGCTTGβ 3180
CGTCCACCCT βCACAGCATC ACTGAATCAC AGAGCCTTTG CGTGAAACAG CTCTGCCAGG 3240
CCβGGAGCTG GGTTTCTCTT CCCTTTTTAT CTGCTβGTGT GGACCACACC TGGGCCTGGC 3300
CGGAGGAAGA GAGAGTTTAC CAAGAGAGAT GTCTCCGGGC CCTTATTTAT TATTTAAACA 3360
TTTTTTTAAA AAGCACTGCT AGTTTACTTG TCTCTCCTCC CCATCGTCCC CATCGTCCTC 3420
CTTGTCCCTG ACTTGGGGCA CTTCCACCCT CACCCAβCCA βTCCACCTCT GCCTTGCCGG 3480
CTCTCCAGAG TAGACATAGT GTGTGGGGTT ββAGCTCTGG CAccceeeβA GGTAβCATTT 3540
CCCTGCAβAT GGTACAGATG TTCCTGCCTT AGAGTCATCT CTAGTTCCCC ACCTCAATCC 3600
CGGCATCCAG CCTTCAGTCC CGCCCACGTG CTAβCTCCGT GGGCCCACCG TGCGGCCTTA 3660
GAGGTTTCCC TCCTTCCTTT CCACTGAAAA GCACATGGCC TTGGGTGACA AATTCCTCTT 3720
TGATGAATGT ACCCTGTGGG GATGTTTCAT ACTGACAGAT TATTTTTATT TATTCAATβT 3780
CATATTTAAA ATATTTATTT TTTATACCAA ATGAATCACT TTTTTTTTTA AGAAAAAAAA 3840
GAGAAATGAA TAAAGAATCT ACTCTTCG 3868
Seq ID NO: C173 DNA Sequence Nucleic Acid Accession ff: XM_097508 Coding sequence: 44..2788
1 11 21 31 41 51
T IGAAAGGCGG TITGTGGTGCA AIAGGAAAACC CIACAGGCCAA GIGAATGGGAA GIACCAAGGTT 60
GACACTTGTT TGTCACGTGT CAATAATCAT CTCTGCCCGβ βACCTCAGCA TGAACAACCT 120
CACAGAGCTT CAGCCTGGCC TCTTCCACCA CCTGCGCTTC TTGGAGGAGC TGCβTCTCTC 180
TGGGAACCAT CTCTCACACA TCCCAGGACA AGCATTCTCT GGTCTCTACA GCCTGAAAAT 240
CCTGATGCTG CAGAACAATC AGCTGGGAGG AATCCCCGCA GAGGCGCTGT GGGAGCTGCC 300
GAGCCTGCAG TCGCTGCGCC TAGATGCCAA CCTCATCTCC CTGGTCCCGG AGAGGAGCTT 360
TGAβGGGCTG TCCTCCCTCC GCCACCTCTG GCTGGACGAC AATGCACTCA CββAβATCCC 420
TGTCAGGGCC CTCAACAACC TCCCTGCCCT GCAGGCCATG ACCCTGGCCC TCAACCGCAT 480
CAGCCACATC CCCGACTACG CGTTCCAGAA TCTCACCAGC CTTGTGGTGC TGCATTTGCA 540
TAACAACCGC ATCCAGCATC TGGGGACCCA CAGCTTCGAG GGGCTGCACA ATCTGβAGAC 600
ACTAGACCTG AATTATAACA AGCTGCAGGA GTTCCCTGTG GCCATCCGGA CCCTGGGCAG 660
ACTGCAGGAA CTGGGGTTCC ATAACAACAA CATCAAGGCC ATCCCAGAAA AGGCCTTCAT 720
GGGGAACCCT CTGCTACAGA CGATACACTT TTATGATAAC CCAATCCAGT TTGTGβGAAG 780
ATCGGCATTC CAGTACCTGC CTAAACTCCA CACACTATCT CTGAATGGTG CCATGβACAT 840
CCAGGAGTTT CCAGATCTCA AAGGCACCAC CAGCCTGGAG ATCCTGACCC TGACCCGCGC 900
AGGCATCCGG CTGCTCCCAT CGGGGATGTG CCAACAGCTG CCCAGGCTCC GAGTCCTGGA 960
ACTGTCTCAC AATCAAATTG AGGAGCTGCC CAGCCTGCAC AGGTGTCAGA AATTGβAGGA 1020
AATCGGCCTC CAACACAACC GCATCTGGGA AATTGGAGCT GACACCTTCA GCCAβCTGAG 1080
CTCCCTβCAA GCCCTGGATC TTAGCTβGAA CGCCATCCGG TCCATCCACC CCGAGGCCTT 1140
CTCCACCCTC CACTCCCTGG TCAAGCTGβA CCTGACAGAC AACCAGCTGA CCACACTCCC 1200
CCTGGCTGGA CTTGGGGGCT TGATGCATCT GAAGCTCAAA GGGAACCTTG CTCTCTCCCA 1260
GGCCTTCTCC AAGGACAGTT TCCCAAAACT GAGGATCCTG GAGβTGCCTT ATGCCTACCA 1320
GTGCTGTCCC TATGGGATGT GTGCCAGCTT CTTCAAGGCC TCTGβGCAGT GGβAGGCTGA 1380
AβACCTTCAC CTTCATGATG AGGAGTCTTC AAAAAGGCCC CTGGGCCTCC TTGCCAGACA 1440
ACCAGAGAAC CACTATGACC AGGACCTGGA TGAGCTCCAG CTGGAGATGG AGGACTCAAA 1500
GCCACACCCC AGTGTCCACT GTAGCCCTAC TCCAGGCCCC TTCAAGCCCT GTGAGTACCT 1560
CTTTGAAAGC TGGGGCATCC GCCTGGCCGT GTGGGCCATC GTGTTGCTCT CCGTGCTCTG 1620
CAATGGACTG GTGCTGCTGA CCGTGTTCGC TGGCGGGCCT GTCCCCCTGC CCCCGGTCAA 1680
GTTTGTGGTA GGTGCGATTG CAGGCGCCAA CACCTTGACT GGCATTTCCT GTGGCCTTCT 1740
AGCCTCAGTC GATGCCCTGA CCTTTGGTCA GTTCTCTGAG TACGGAGCCC GCTGGGAGAC 1800
GGGGCTAGGC TGCCGGGCCA CTGGCTTCCT GβCAGTACTT GGGTCGGAGG CATCGGTGCT 1860
GCTGCTCACT CTGGCCGCAG TGCAGTGCAβ CGTCTCCGTC TCCTCTGTCC GGGCCTATGG 1920
GAAGTCCCCC TCCCTGGGCA GCGTTCGAGC AGGGGTCCTA GGCTGCCTGG CACTGβCAGG 1980
GCTGGCCGCC GCGCTGCCCC TGGCCTCAGT GGGAGAATAC GGGGCCTCCC CACTCTGCCT 2040
GCCCTACGCG CCACCTGAβG GTCAβCCAGC AGCCCTGGGC TTCACCGTGG CCCTGGTGAT 2100
GATGAACTCC TTCTGTTTCC TGGTGGTGGC CGGTGCCTAC ATCAAACTGT ACTGTGACCT 2160
GCCGCGGGGC GACTTTGAGG CCGTGTGGGA CTGCGCCATG GTGAGGCACG TGGCCTGGCT 2220
CATCTTCGCA GACGGGCTCC TCTACTGTCC CGTGGCCTTC CTCAGCTTTG CCTCCATCCT 2280
GGGCCTCTTC CCTGTCACGC CCGAGGCCGT CAAGTCTGTC CTGCTGβTGG TGCTGCCCCT 2340
GCCTGCCTGC CTCAACCCAC TGCTGTACCT GCTCTTCAAC CCCCACTTCC GββATβACCT 2400
TCGGCGGCTT CGGCCCCGCG CAGGGGACTC AGβGCCCCTA GCCTATGCTG CGGCCGGGGA 2460
GCTGGAGAAG AGCTCCTGTG ATTCTACCCA GGCCCTGGTA GCCTTCTCTG ATGTGβATCT 2520
CATTCTGGAA GCTTCTGAAG CTGGGCGGCC CCCTGGGCTβ GAGACCTATC βCTTCCCCTC 2580
AGTGACCCTC ATCTCCTGTC AGCAGCCAGG GGCCCCCAGG CTGGAGGGCA GCCATTGTGT 2640
AGAGCCAGAG GGGAACCACT TTGGGAACCC CCAACCCTCC ATGGATGGAG AACTGCTGCT 2700
GAGGGCAGAG GGATCTACGC CAGCAGGTGG AGGCTTCTCA GGGGGTGGCG GCTTTCAGCC 2760
CTCTGGCTTG GCCTTTGCTT CACACGTGTA AATATCCCTC CCCATTCTTC TCTTCCCCTC 2820
TCTTCCCTTT CCTCTCTCCC CCTCGGTGAA TCATGGCTGC TTCTAAAACA AATACAACCA 2880
AAACTCAGCA GTGTGATCTA TAGCAGGATβ βCCCAGTCCC TGGCTCCACT GATCACCTCT 2940
CTCCTGTGAC CATCACCAAC GGGTGCCTCT TGGCCTGGCT TTCCCTTGβC CTTCCTCAGC 3000
TTCACCTTGA TACTGGGCCT CTTCCTTGTC ATGTCTGAAG CTGTCGACCA GAGACCTGGA 3060
CTTTTGTCTG CTTAAGββAA AT6AGGGAAG TAAAGACAGT GAAGGGβTββ AGGGTTGATC 3120
AGGGCACAGT GGACAGβGAG ACCTCACAGA GAAAGGCCTβ βAAGGTGATT TCCCGTGTGA 3180
CTCATGGATA GGATACAAAA TGTGTTCCAT GTACCATTAA TCTTGACATA TGCCATGCAT 3240
AAAGACTTCC TATTAAAATA AGCTTTGGAA GAG 3273
Seq ID NO: C174 DNA Sequence Nucleic Acid Accession ft: NM 130849 Coding sequence: 101..2044
11 21 31 41 51
I I I I I
AGTCTGβCCC TGGACAACCC CAGCAAAGCC βCCCTCAGCC AGCCCAGAAG CACTGGGCCT 60 TββCCACAβC AACACCCACT GAGCACGCTG GβAGCTGAGT ATGGCGTCCC TGGTCTCGCT 120 βGAGCTGGGG CTGCTTCTGG CTGTGCTGGT GGTGACGGCβ ACGGCGTCCC CGCCTGCTGG 180 TCTGCTGAGC CTGCTCACCT CTGGCCAGGG CGCTCTGGAT CAAGAGGCTC TGGGCGGCCT 240 GTTAAATACG CTGGCGGACC GTGTGCACTG CACCAACGGG CCGTGTGGAA AGTGCCTGTC 300 TGTGGAGGAC GCCCTGGGCC TGGGCGAGCC TGAGGGGTCA GGGCTGCCCC CGGGCCCGβT 360 CCTGGAGGCC AGGTACGTCG CCCGCCTCAG TGCCβCCβCC GTCCTGTACC TCAGCAACCC 420 CGAGGGCACC TGTGAGGACA CTCGGGCTββ CCTCTGGGCC TCTCATGCAG ACCACCTCCT 480 GGCCCTGCTC GAGAGCCCCA AGGCCCTGAC CCCGGGCCTG AGCTGGCTGC TGCAGAGGAT 540 GCAGGCCCGG GCTGCGGGCC AβACCCCCAA GACCβCCTGC GTAGATATCC CTCAGCTGCT 600 GGAGGAGGCG CTGββGGCGG GββCTCCGGG CAGTβCTGGC GGCGTCCTGG CTGCCCTGCT 660 GGACCATGTC AGGAGCGGGT CTTGCTTCCA CGCCTTGCCG AGCCCTCAGT ACTTCGTGGA 720 CTTTGTGTTC CAGCAGCACA GCAGCGAGGT CCCTATGACG CTGGCCGAGC TGTCAGCCTT 780 GATGCAGCGC CTGGGGGTGG GCAGGGAGGC CCACAGTGAC CACAGTCATC GGCACAGGGG 840 AGCCAGCAGC CGGGACCCTG TGCCCCTCAT CAGCTCCAGC AACAGCTCCA GTGTGTCββA 900 CACGGTATGC CTGAGTGCCA GGGACGTβAT GGCTGCATAT GGACTGTCGG AACAGGCTGG 960 GGTGACCCCG GAGGCCTGGβ CCCAACTβAβ CCCTGCCCTG CTCCAACAGC AGCTGAGTGG 1020 AGCCTGCACC TCCCAGTCCA GβCCCCCCGT CCAGGACCAG CTCAGCCAGT CAGAβAGGTA 1080 TCTGTACGGC TCCCTGGCCA CGCTGCTCAT CTGCCTCTGC GCGGTCTTTG GCCTCCTCCT 1140 GCTCACCTGC ACTGGCTGCA GGGGGGTCGC CCACTACATC CTGCAβACCT TCCTGAβCCT 1200 GGCAGTGGGT GCACTCACTG GGGACGCTGT CCTGCATCTG ACGCCCAAGG TGCTGβGGCT 1260 GCATACACAC AGCGAAGAGG GCCTCAGCCC ACAGCCCACC TGGCβCCTCC TGGCTATGCT 1320 GGCCGGGCTC TACGCCTTCT TCCTGTTTβA GAACCTCTTC AATCTCCTGC TGCCCAGGGA 1380 CCCGGAGGAC CTGGAGGACG GGCCCTGCGG CCACAGCAGC CATAGCCACG GGGGCCAGAG 1440 CCACGGTGTG TCCCTGCAGC TGGCACCCAG CGAGCTCCGG CAGCCCAAGC CCCCCCACGA 1500 ββecTcccec GCAGACCTGG TGGCGGAGGA GAGCCCGGAG CTGCTGAACC CTGAGCCCAG 1560
GAGACTGAβC CCAGAGTTGA GGCTACTGCC CTATATGATC ACTCTGGGCG ACGCCGTGCA 1620 CAACTTCGCC GACGGGCTGG CCGTββGCGC CCCCTTCGCG TCCTCCTGGA AGACCGGβCT 1680 GGCCACCTCG CTGGCCGTGT TCTGCCACGA GTTGCCACAC GAGCTGGGGG ACTTCGCCGC 1740 CTTGCTCCAC GCGGGGCTGT CCGTGCGCCA AGCACTGCTG CTGAACCTGG CCTCCGCGCT 1800 CACGGCCTTC GCTGGTCTCT ACGTGGCACT CGCGGTTGGA GTCAGCGAGG AGAGCGAGGC 1860 CTGGATCCTG GCAGTGGCCA CCGGCCTGTT CCTCTACGTA GCACTCTGCβ ACATGCTCCC 1920 GGCGATβTTG AAAGTACGGG ACCCGCGGCC CTGGCTCCTC TTCCTGCTGC ACAACCTββG 1980 CCTGCTGGGC GGCTGGACCG TCCTGCTGCT GCTGTCCCTG TACGA∞ATG ACATCACCTT 2040 CTGATACCCT GCCCTAGTCC CCCACCTTTG ACTTAAGATC CCACACCTCA CAAACCTACA 2100 GCCCAGAAAC CAGAAGCCCC TATAGAGGCC CCAGTCCCAA CTCCAGTAAA GACACTCTTG 2160 TCCTTGβAAA AAAAAAAAAA AAAAAAAAAA AA 2192
Seq ID NO: C175 DNA Sequence Nucleic Acid Accession #: NM_018971 Coding sequence: 1..1128
11 21 31
ATGGCGAACG CGAGCGAGCC GGGTGGCAGC GGCGGCGGCG AGGCGGCCGC CCTGGGCCTC 60
AAGCTGGCCA CGCTCAGCCT GCTGCTGTGC GTGAGCCTAG CGGGCAACGT GCTGTTCβCG 120
CTGCTGATCG TGCGGGAGCG CAGCCTGCAC CGCβCCCCβT ACTACCTGCT GCTCβACCTG 180
TGCCTGGCCG ACGGGCTGCG CGCGCTCGCC TGCCTCCCGG CCβTCATβCT GGCGGCβCGG 240
CGTGCGGCGG CCGCGGCGββ eecβcceccβ GβCβCGCTGG eCTGCAAGCT GCTCGCCTTC 300
CTGGCCGCGC TCTTCTGCTT CCACGCCGCC TTCCTGCTGC TGGGCGTGGG CGTCACCCGC 360
TACCTββCCA TCGCGCACCA CCGCTTCTAT GCAGAGCGCC TGGCCGGCTG GCCGTGCGCC 420
GCCATGCTGG TGTGCGCCGC CTGGGCGCTG GCGCTGGCCG CGGCCTTCCC GCCAGTGCTG 480
GACGGCGGTG GCGACGACGA GGACGCGCCG TGCβCCCTβG AGCAGCGGCC CGACGGCGCC 540
CCCGGCGCGC TGGGCTTCCT GCTGCTGCTG GCCGTGGTGG TGGGCGCCAC GCACCTCGTC 600
TACCTCCGCC TGCTCTTCTT CATCCACGAC CGCCGCAAGA TGCGGCCCGC GCGCCTGGTG 660
CCCGCCGTCA GCCACGACTG GACCTTCCAC GGCCCGGGCG CCACCGGCCA GGceeccβcc 720
AACTGGACGG CGGGCTTCGG CCGCGGGCCC ACGCCβCCCβ CGCTTGTβββ CATCCGGCCC 780
GCAGGGCCGG GCCGCGGCGC GCβCCGCCTC CTCGTβCTGG AAGAATTCAA GACGGAGAAG 840
AGGCTGTGCA AGATGTTCTA CGCCGTCACG CTGCTCTTCC TGCTCCTCTG GGGGCCCTAC 900
GTCGTGGCCA GCTACCTGCG GGTCCTGGTG CGGCCCGGCG CCGTCCCCCA GGCCTACCTG 960
ACGGCCTCCG TGTGGCTGAC CTTCGCGCAG GCCGGCATCA ACCCCGTCGT GTGCTTCCTC 1020
TTCAACAGGG AGCTGAGGGA CTGCTTCAGβ GCCCAGTTCC CCTGCTGCCA GAGCCCCCGG 1080
ACCACCCAGG CGACCCATCC CTGCGACCTβ AAAGGCATTG GTTTATGA 1128
Seq ID NO: C176 DNA Sequence Nucleic Acid Accession # : NM_005631 Coding sequence : 290 . .2653
11 21 31 41 51
I I I I I
GGCACGAGGG GGCTGAAGAG AACTTGGATT GCGAGGCTAG GGCTTGGGGA GTCGTGCATC 60 CCGTTCCGββ CCTCCGCAGC CCAACATGGG CCCCGGGTTC CAAAGTTTGC GAAGTTGGGC 120 βCCGAGGGGC CGGGGCGCGC GGAGCGTCCG GGGGGGCCCG GGCCCGGATT CTCTGGGCGC 180 ACAGGTCGCC TGAGCCGCCT CCGCGGCCGC CGAGGTCGTG CGTGTGGCCG GGGGGCTCCG 240 AGGAGCAββC GGGGGCGCCG G6GCTTTTGC TGAGTTGGCG GGβTTGGCCA TGGCCGCTGC 300 CCGCCCAGCG CGGGGGCCGG AGCTCCCGCT CCTGGGGCTG CTGCTGCTGC TGCTGCTGGG 360 GGACCCGGGC CGGGGGGCGG CCTCGAGCGG GAACGCGACC GGGCCTGGGC CTCGGAGCGC 420 GGGCGGGAGC GCGAGGAGβA GCGCGGCGGT GACTGGCCCT CCGCCGCCGC TGAGCCACTG 480 CGGCCGGGCT GCCCCCTGCG AGCCGCTGCG CTACAACGTG TCCCTGGGCT CGGTGCTGCC 540 CTACGGGGCC ACCTCCACAC TGCTGGCCGG AGACTCGGAC TCCCAGGAGG AAGCGCACGG 600 CAAGCTCGTG CTCTGβTCβG GCCTCCGGAA TGCCCCCCGC TGCTGGGCAG TGATCCAGCC 660 CCTGCTGTGT GCCGTATACA TGCCCAAGTG TGAGAATGAC CGGGTGGAGC TGCCCAGCCG 720 TACCCTCTGC CAGGCCACCC GAGGCCCCTC TGCCATCGTG GAGAGβGAGC GGGGCTGGCC 780 TGACTTCCTG CGCTGCACTC CTGACCGCTT CCCTGAAGGC TGCACβAATG AGGTGCAGAA 840 CATCAAGTTC AACAGTTCAG GCCAGTGCβA AGTGGCCTTG GTTCGGACAG ACAACCCCAA 900 GAGCTGGTAC GAGGAGGTGG AGGGCTGCββ CATCCAGTGC CAGAACCCGC TCTTCACAGA 960 GGCTGAGCAC CAGGACATGC ACAGCTACAT CGCGGCCTTC GGGGCCGTCA CGGGCCTCTG 1020 CACGCTCTTC ACCCTGGCCA CATTCGTGGC TGACTGβCCG AACTCGAATC GCTACCCTGC 1080 TGTTATTCTC TTCTACGTCA ATGCGTGCTT CTTTGTGGGC AGCATTGGCT GβCTGGCCCA 1140 GTTCATGGAT GGTGCCCGCC GAGAGATCGT CTGCCGTGCA GATGβCACCA TGAGGCTTGG 1200 GGAGCCCACC TCCAATGAGA CTCTGTCCTG CβTCATCATC TTTGTCATCG TGTACTACGC 1260 CCTGATGGCT GβTGTβGTTT ββTTTGTGGT CCTCACCTAT GCCTGGCACA CTTCCTTCAA 1320 AGCCCTGGGC ACCACCTACC AGCCTCTCTC GGGCAAGACC TCCTACTTCC ACCTGCTCAC 1380 CTGGTCACTC CCCTTTGTCC TCACTGTGGC AATCCTTGCT GTGGCβCAGG TGGATGGGGA 1440 CTCTGTGAGT GGCATTTGTT TTGTGGGCTA CAAGAACTAC CGATACCGTG CGGGCTTCGT 1500 GCTGGCCCCA ATCGGCCTGG TGCTCATCGT GGGAGGCTAC TTCCTCATCC GAGGAGTCAT 1560 GACTCTGTTC TCCATCAAGA GCAACCACCC CGGGCTGCTG AβTβAGAAGG CTGCCAGCAA 1620 GATCAACGAG ACCATGCTGC GCCTGGGCAT TTTTGGCTTC CTGGCCTTTG GCTTTGTGCT 1680 CATTACCTTC AGCTGCCACT TCTACGACTT CTTCAACCAG GCTGAGTGGG AGCGCAGCTT 1740 CCGGGACTAT GTGCTATGTC AGGCCAATGT GACCATCGGG CTGCCCACCA AGCAGCCCAT 1800 CCCTGACTGT GAGATCAAGA ATCGCCCGAG CCTTCTβGTβ GAGAAGATCA ACCTGTTTGC 1860 CATGTTTGGA ACTGGCATCG CCATGAGCAC CTGGGTCTCG ACCAAGGCCA CGCTGCTCAT 1920 CTGGAGGCGT ACCTGGTGCA GGTTGACTGβ GCA6AGTGAC GATGAGCCAA AGCGGATCAA 1980 GAAGAβCAAG ATGATTCCCA AGGCCTTCTC TAAGCGGCAC GAGCTCCTGC AGAACCCAGG 2040 CCAGGA6CTC TCCTTCAGCA TGCACACTGT GTCCCAGGAC GGGCCCGTGG CGGGCTTGGC 2100 CTTTGACCTC AATGAGCCCT CAGCTGATGT CTCCTCTGCC TGGGCCCAGC ATβTCACCAA 2160 GATGGTGGCT CGGAGAGGAG CCATACTGCC CCAGGATATT TCTGTCACCC CTGTGGCAAC 2220 TCCA6TGCCC CCAGAGGAAC AAGCCAACCT GTGGCTGβTT βAGGCAGAGA TCTCCCCAGA 2280 GCTGCAβAAG CGCCTGGGCC GGAAGAAGAA GAGGAGGAAG AGGAAGAAGG AββTβTβCCC 2340 GCTGGCGCCG CCCCCTGAGC TTCACCCCCC TGCCCCTGCC CCCAGTACCA TTCCTCβACT 2400 GCCTCAGCTβ CCCCGβCAβA AATGCCTCβT GGCTGCAGGT GCCTGGGGAG CTGGGGACTC 2460 TTGCCGACAG GGAGCGTGGA CCCTGGTCTC CAACCCATTC TGCCCAGAGC CCAGTCCCCC 2520 TCACGATCCA TTTCTGCCCA βTβCACCββC CCCCGTGGCA TGGGCTCATG GCCGCCβACA 2580 GGGCCTGGGG CCTATTCACT CCCβCACCAA CCTGATGGAC ACAGAACTCA TGGATGCAGA 2640 CTCGβACTTC TGA6CCTCCA GAGCAββACC TGGGACAGGA AAGAGAGGAA CCAATACCTT 2700 CAAG6CTCTT CTTCCTCACC βAβCATGCTT CCCTAGGATC CCGTCTTCCA GAGAACCTGT 2760 GβGCTGACTβ CCCTCCGAAG AβAβTTCTβG ATGTCTGGCT CAAAGCAGCA GGACTGTGGG 2820 AAAGAβCCTA ACATCTCCAT βGGβAGGCCT CACCCCAGGG ACAGGGCCCT GGAGCTCAGG 2880 GTCCTTGTTT CTGCCCTCCC AGCTGCAβCC TGGTTGGCAG CATCTGCTCC ATCGGGβCAG 2940 GβGGTATGCA βAGCTTGTGβ TβGGGCAGGA ACGGTGGAGG CAGAGGTGAC AGTTCCCAGA 3000 GTGβGCTTTG βTββCCAGGG AGGCAGCCTA GCCTATGTCT GGCAGATCAG GβCTββCTGC 3060 CGTTTTCTGG GCTGATGGGT βCCCTTTCCT GGCAGTCTCA GTCCAAAAGT GTTGACTGTG 3120 TCATTAGTCC TTTGTCTAAβ TAGGGCCAGG GCACCGTATT CCTCTCCCAG GTGTTTGTGG 3180 GGCTGGAAGβ ACCTβCTCCC ACAGβGGCCA TGTCCTCTCT TAATAGGTGG CACTACCCCA 3240 AACCCATCTT TTGTTCTCCT ATATCCTCCT TCTCCTGTTC CATTTCAGTT CAGTTTCAGC 3300 ββTCCCAACC TCTTTGCGTT TCCTTTTTGT TGATβAGGAC CCAGAGCTGC TGCACACACT 3360 CACCTCTAAC CCCCTCCCCT CGCTGCTCGβ CCCCATCTCC ACAGGAGAGA , CTGGTTCGGC 3420 TCTAGGGCCT CAGTCTGGAG TGGGATAββA GCAGTGAGTG ACAAAGCCTC TGAAAGATGC 3480 ATCATCTCTT CCTCACACCC ATTTAGTGGG GGATGGGTCC TCTAGACTTG AGGGGCTACC 3540 CTGGGAAGCT GCCβTAGCTT CAGCCAGβCA AGAAAGCTTC CTTCAACCTG - CATAGCCGβT 3600 GGGTGAGGAG ATTCCCACCT TCCATAGCCT CCAAACATGT TCCCAAGGCC ! CCACTTTCAA 3660 CAATCAGACA GCAGGAAGCC ATAGATGCTG GCTGββTTCC AββTTATGGG i GAGAAGAAAT 3720 ACACTCAATA AAAGGTTTTT GTATAAAAAA AAAAAAAAAA AAAAAAAAAA . AAAAAAAAAA 3780 A 3781
Seq ID NO: C177 DNA Sequence Nucleic Acid Accession ff: AK094595 Coding sequence: 1..2853
11 21 31 51
ATGGGGGCCC GGAGCGGAGC TCGGGGCGCβ CTGCT6CTGG CACTGCTGCT CTGCTGGGAC 60
CCGAGGCTGA GCCAAGCAGG TAGGAAβCGA TGGGGTGAGG TGCTCCCTGA CTCCTTCCCG 120
TCAGCGCCAG CAGAβCCβCT βCCCTACTTC CTGCAGGAGC CACAGGACGC CTACATTGTG 180
AAGAACAAGC CTβTGGAGCT CCGCTGCCGC GCCTTCCCCG CCACACAGAT CTACTTCAAG 240
TGCAACGGCG AGTGGGTCAG CCAGAACGAC CACGTCACAC AGGAAGGCCT GGATGAGGCC 300
ACCCTGGGGG CGCGGGGCGG CCTGCGGGTG CGCGAGGTGC AGATCGAGGT GTCGCGGCAG 360
CAGGTGGAGG AGGTCTTTGG GCTGGAGGAT TACTGGTGCC AGTGCGTGGC CTGGAGCTCC 420
GCGGGCACCA CCAAGAGTCG CCGAGCCTAC GTCCGCATCG CCTACCTCCβ CAAGAACTTC 480
GATCAGGAGC CTCTGGGCAA GGAGGTGCCC CTGGACCATG AGGTTCTCCT GCAGTGCCGC 540
CCGCCGGAGG GGCTGGCTGT GGCCGAGGTG βAATGGCTCA AβAATGAGGA TGTCATCGAC 600
CCCACCCAGG ACACCAACTT CCTGCTCACC ATCGACCACA ACCTCATCAT CCGCCAGGCC 660
CGCCTGTCGG ACACTGCCAA CTATACCTGC GTGGCCAAGA ACATCGTGGC CAAACGCCGG 720
AGCACCACTG CCACCGTCAT CGTCTACGTG AATGGCGGCT GGTCCAGCTG GGCAGAGTGG 780
TCACCCTGCT CCAACCGCTG TGGCCGAGGC TGGCAGAAβC GCACCCGGAC CTGCACCAAC 840
CCCGCTCCAC TCAACGGAGG GGCCTTCTGC GAGGGCCAGG CATTCCAGAA GACCGCCTβC 900
ACCACCATCT GCCCAGTCGA TGGGGCCTGG ACGGAGTGGA GCAAGTGGTC AβCCTGCAGC 960
ACTGAGTGTG CCCACTGGCG TAGCCCCCAG TGCATGGCGC CCCCACCCCA GAACGGAββC 1020
CGTGACTGCA GCGGGACGCT GCTCGACTCT AAGAACTGCA CAGATGGGCT GTGCATGCAA 1080
AATAAGAAAA CTCTAAGCGA CCCCAACAβC CACCTGCTGG AGGCCTCAGG GGATGCGGCG 1140
CTGTATGCGG GβCTCGTGGT GGCCATCTTC βTGGTCGTGG CAATCCTCAT GGCGGTGGGG 1200
GTGGTGGTGT ACCGCCGCAA CTGCCGTGAC TTCGACACAG ACATCACTGA CTCATCTGCT 1260
GCCCTGACTG GT6GTTTCCA CCCCGTCAAC TTTAAGACGG CAAGGCCCAG CAACCCGCAG 1320
CTCCTACACC CCTCTGTGCC TCCTGACCTG ACAGCCAGCG CCGGCATCTA CCGCGβACCC 1380 GTGTATGCCC TGCAGGACTC CACCGACAAA ATCCCCATGA CCAACTCTCC TCTGCTGGAC 1440
CCCTTACCCA GCCTTAAGβT CAAGGTCTAC AGCTCCAGCA CCACGGGCTC TGGGCCAGGC 1500
CTGGCAβATG GGGCTGACCT GCTGGGGGTC TTGCCGCCTG GCACATACCC TAGCGATTTC 1560
GCCCGGGACA CCCACTTCCT GCACCTGCGC AGCβCCAGCC TCGGTTCCCA GCAGCTCTTG 1620
GGCCTGCCCC GAGACCCAGG GAGCAGCGTC AGCββCACCT TTGβCTβCCT GGGTGGGAGG 1680
CTCAGCATCC CCGGCACAGβ GβTCAGCTTG CTβGTGCCCA ATGGAGCCAT TCCCCAGβGC 1740
AAGTTCTACG AGATGTATCT ACTCATCAAC AAGGCAGAAA GTACCCTCCC GCTTTCAGAA 1800
GGGACCCAGA CAGTATTGAG CCCCTCGβTG ACCTGTGGAC CCACAG6CCT CCTGCTGTGC 1860
CGCCCCGTCA TCCTCACCAT βCCCCACTβT GCCGAAGTCA CTGCCCGTGA CTGGATCTTT 1920
CAGCTCAAGA CCCAGGCCCA CCAGGGCCAC TGGGAGGAGG TC6TCACCCT GβATGAGGAG 1980
ACCCTGAACA CACCCTGCTA CTGCCAGCTG GAGCCCAGGG CCTGTCACAT CCTGCTGGAC 2040
CAGCTGGGCA CCTACGTGTT CACGGGCβAG TCCTATTCCC GCTCAGCAGT CAAGCGGCTC 2100
CAGCTGGCCG TCTTCGCCCC CGCCCTCTGC ACCTCCCTGG AGTACAGCCT CCGGGTCTAC 2160
TGCCTGGAGG ACACGCCTGT AGCACTGAAG GAGGTGCTGG AGCTGGAGCG GACTCTGGGC 2220
GGATACTTGG TGGAGGAGCC GAAACCGCTA ATGTTCAAGG ACAGTTACCA CAACCTGCGC 2280
CTCTCCCTCC ATGACCTCCC CCATGCCCAT TGGAGGAGCA AGCTGCTGGC CAAATACCAG 2340
GAGATCCCCT TCTATCACAT TTGGAGTGGC AGCCAGAAGG CCCTCCACTG CACTTTCACC 2400
CTGGAGAGGC ACAGCTTGGC CTCCACAGAG CTCACCTGCA AGATCTGCGT GCβGCAAGTG 2460
GAAGGGGAGG GCCAGATATT CCAGCTGCAT ACCACTCTGG CAGAGACACC TGCTGGCTCC 2520
GTGGACACTC TCTGCTCTGC CCCTGGCAGC ACTGTCACCA CCCAGCTGGG ACCTTATGCC 2580
TTCAAGATCC CACTGTCCAT CCGCCAGAAG ATATGCAACA GCCTAGATGC CCCCAACTCA 2640
CGGGGCAATG ACTGGCGGAT GTTAGCACAG AAGCTCTCTA TGGACCGGTA CCTGAATTAC 2700
TTTGCCACCA AAGCGAGCCC CACGGGTGTG ATCCTGGACC TCTCGGAAGC TCTGCAGCAG 2760
GACβATβeee ACCTCAACAG CCTGGCGAGT GCCTTGGAGG AGATGGGCAA GAGTGAGATG 2820
CTGGTGGCTG TGGCCACCGA CβGGGACTGC TGAGCCTCCT GGGACAGCGβ GCTGGCAGGG 2880
ACTGGCAGβA GGCAGGTGCA βGGAGGCCTβ GGGCAGCCTC CTGATGGGGA TGTTTGβCCT 2940
CTGCTTCCTC CCAGTTCACA GCCAGAGTTG CCTCTCCTCC TCCTCTTCCC CAACCCCCAG 3000
ACCATGACCA GCCTTAGAAA ATCCATGTAC TCTGTTGTTA GAGGβCCCAG AGTTCCTTCT 3060
CCACCCCCGC TCTCTCTCTC TTGGCCTGAG ATCTGTGTGC AGβAACCAAG ATGGGGCTGA 3120
AGCCTCTGGA GGCAGTTβGT TGGGGGCGGG CAGGCAGGAG GCCCTCCCTC CACCCCCCCA 3180
CCCTCAGCCC GGCAACTTCT GGGTTCCATG GGTTTTAGTT CCGTTCTCGT TTTCTTCCTC 3240
CGTTATTGAT TTCTCCTTTC TCCCTAAGCC CCCTTCTGCT TCCACGCCCT TTTCCTCTTT 3300 βAAGAGTCAA GTACAATTCA GACAAACTCC TTTCTCGTGT CCAAAAGCAA AAAGGCAAAG 3360
GAAAβAAAGA AAGCTTCAβA CCβCTAβTAA GGCTCAAAGA AGAAGAAAAA CACCAAAACC 3420
ACAAGG6AAA AGAAAAACCC AGTTTCTTAG βAAACβCAAA CGATTTATTA TCCAGATTAT 3480
TTGGATAAGT CCTTTTTAAA A 3501
Seq ID NO: C178 DNA Sequence Nucleic Acid Accession #: NM_004625 Coding sequence: 310..1359
11 21 31
GAGGGAGGGG CGGGGGCTGG AGGCAβCAGC GCCCCCGCAC TCCCCGCGTC TCGCACACTT 60
GCACCGGTCC CTCGCGCGCA GCCCGGCGTC GCCCCACGCC GCGCTCGCTC CTCCCTCCCT 120
CCTCCCGCTC CGTGGCTCCC GTGCTCCTGG CGAGGCTCAG GCGCGGAβCβ CGCGGACGβG 180
CGCACCGACA GACGGCCCCG GGGACGCCTC GGCTCGCGCC TCCCGββCGG GCTATGTTGA 240
TTGCCCCGCC GGGβCCGGCC CGCGGGATCA GCACAGCCCG GCCCGCGGCC CCGGCGGCCA 300
ATCGGGACTA TGAACCGGAA AGCGCGGCGC TGCCTGGGCC ACCTCTTTCT CAGCCTGGGC 360
ATGGTCTACC TCCGGATCGG TGGCTTCTCC TCAGTGGTAG CTCTGGGCGC AAGCATCATC 420
TGTAACAAGA TCCCAGGCCT GGCTCCCAGA CAGCGGGCGA TCTGCCAGAG CCGGCCCGAC 480
GCCATCATCC TCATAGGAGA AGGCTCACAA ATGGGCCTGG ACGAGTGTCA GTTTCAGTTC 540
C6CAATGGCC GCTGGAACTG CTCTGCACTG GGAGAGCGCA CCGTCTTCGG GAA6GAGCTC 600
AAAGTGβeβA GCCGGGAGGC TGCGTTCACC TACGCCATCA TTGCCGCCβG CGTGGCCCAC 660
GCCATCACAβ CTGCCTGTAC CCAGGGCAAC CTGAGCGACT GTββCTGCGA CAAAGAGAAG 720
CAAGGCCAGT ACCACCGGGA CGAββGCTGG AAGTGGGGTG GCTGCTCTGC CGACATCCGC 780
TACGGCATCG GCTTCGCCAA GGTCTTTGTG GATGCCCGGG AGATCAAGCA GAATGCCCGG 840
ACTCTCATGA ACTTGCACAA CAACGAGGCA GGCCGAAAGA TCCTGGAGGA GAACATGAAG 900
CTGGAATGTA AGTGCCACGG CGTβTCAGGC TCGTGCACCA CCAAGACGTG CTGGACCACA 960
CTGCCACAβT TTCGGGAGCT GGGCTACGTG CTCAAGGACA AGTACAACGA GβCCβTTCAC 1020
GTGGAGCCTG TGCβTβCCAC CCGCAACAAG CGGCCCACCT TCCTGAAGAT CAAGAA6CCA 1080
CTGTCGTACC GCAAGCCCAT GGACACGGAC CTGGTGTACA TCGAGAAβTC GCCCAACTAC 1140
TGCGAGGAGG ACCCGGTGAC CGGCAβTGTG GGCACCCAββ GCCGCβCCTG CAACAAGACG 1200
GCTCCCCAGG CCAGCGGCTG TGACCTCATG TGCTGTGGGC GTGGCTACAA CACCCACCAG 1260
TACGCCCGCG TGTGGCAGTG CAACTGTAAG TTCCACTGβT GCTGCTATGT CAAGTGCAAC 1320
ACGTGCAGCG AGCβCACβGA GATGTACACG TGCAAGTGAG CCCCGTGTGC ACACCACCCT 1380
CCCGCTGCAA GTCAGATTGC TGGGAGGACT GGACCGTTTC CAAGCTGCGG GCTCCCTGGC 1440
AGGATGCTGA GCTTGTCTTT TCTGCTGAGG AGGGTACTTT TCCTGGGTTT CCTGCACGCA 1500
TCCGTβGGGG AAAAAAAATC TCTCAGAGCC CTCAACTATT CTGTTCCACA CCCAATGCTG 1560
CTCCACCCTC CCCCAGACAC AGCCCAGGTC CCTCCGCGGC TGGAGCGAAG CCTTCTGCAβ 1620
CAGGAACTCT GGACCCCTGG GCCTCATCAC AGCAATATTT AACAATTTAT TCTGATAAAA 1680
ATAATATTAA TTTATTTAAT TAAAAAGAAT TCTTCCACAA AAAAAAAAAA AAAAAA 1736
Seq ID NO: C179 DNA Sequence OBR3 Nucleic Acid Accession ft-. NM_003786 Coding sequence: 71..4654
11 21 31 41 51
I I I I I
CTCCGβCGCC CGCTCTGCCC GCCGCTGGGT CCGACCGCGC TCGCCTTCCT TGCAGCCGCG 60 CCTCGGCCCC ATGGACGCCC TGTGCGGTTC CGGGGAGCTC GGCTCCAAGT TCTGGGACTC 120 CAACCTGTCT GTGCACACAG AAAACCCGGA CCTCACTCCC TGCTTCCAGA ACTCCCTGCT 180 GGCCTGGGTβ CCCTGCATCT ACCTGTCGGT CGCCCTGCCC TGCTACTTGC TCTACCTGCβ 240 GCACCATTGT CGTGGCTACA TCATCCTCTC CCACCTGTCC AAGCTCAAGA TGGTCCTGGG 300 TGTCCTGCTβ TGGTGCGTCT CCTGGGCGGA CCTTTTTTAC TCCTTCCATG GCCTGGTCCA 360
TGGCCCββCC CCTGCCCCTG TTTTCTTTCT CACCCCCTTG GTCGTGGGGβ TCACCATGCT 420
GCTGGCCACC CTGCTGATAC AGTATGAGCG GCTGCAGβGC GTACAGTCTT CGGββGTCCT 480
CATTATCTTC TβGTTCCTGT GTGTGGTCTG CGCCATCβTC CCATTCCβCT CCAAGATCCT 540
TTTAGCCAAG GCAGAGGGTG AGATCTCAGA CCCCTTCCGC TTCACCACCT TCTACATCCA 600
CTTTGCCCTG GTACTCTCTG CCCTCATCTT GGCCTGCTTC AGGGAGAAAC CTCCATTTTT 660
CTCCGCAAAG AATGTCGACC CTAACCCCTA CCCTGAGACC AGCGCTGGCT TTCTCTCCCG 720
CCTGTTTTTC TGGTGGTTCA CAAAGATGGC CATCTATGGC TACCGGCATC CCCTGGAGGA 780
GAAGGACCTC TGGTCCCTAA AGGAAGAGGA CAGATCCCAG ATCGTGGTGC AGCAGCTGCT 840
GGAGGCATGG AGGAAGCAββ AAAAGCAGAC GβCACGACAC AAGGCTTCAG CAGCACCTGG 900
GAAAAATGCC TCCGβCGAGβ ACβAβGTGCT GCTGGGTGCC CGGCCCAββC CCCGGAAGCC 960
CTCCTTCCTG AAGGCCCTGC TGGCCACCTT CGGCTCCAGC TTCCTCATCA GTGCCTGCTT 1020
CAAGCTTATC CAGGACCTGC TCTCCTTCAT CAATCCACAG CTGCTCAβCA TCCTGATCAG 1080
GTTTATCTCC AACCCCATGG CCCCCTCCTG βTβGGGCTTC CTGGTGGCTG GGCTGATGTT 1140
CCTGTGCTCC ATGATGCAGT CGCTGATCTT ACAACACTAT TACCACTACA TCTTTGTGAC 1200
TGGGβTGAAG TTTCGTACTG GGATCATGGG TGTCATCTAC AGGAAGGCTC TGGTTATCAC 1260
CAACTCAGTC AAACGTGCGT CCACTGTGGG GGAAATTGTC AACCTCATGT CAGTGGATGC 1320
CCAGCGCTTC ATGGACCTTG CCCCCTTCCT CAATCTGCTG TGβTCAβCAC CCCTGCAGAT 1380
CATCCTGβCG ATCTACTTCC TCTGGCAGAA CCTAGGTCCC TCTGTCCTGG CTGGAGTCGC 1440
TTTCATGGTC TTGCTGATTC CACTCAACGG AGCTGTGGCC GTGAAGATGC GCGCCTTCCA 1500
GGTAAAGCAA ATGAAATTGA AGGACTCGCG CATCAAGCTG ATGAGTCAGA TCCTGAACGG 1560
CATCAAGβTG CTGAAGCTGT ACGCCTGGGA GCCCAGCTTC CTGAAGCAGG TGGAGGGCAT 1620
CAGGCAGG6T GAGCTCCAGC TGCTGCGCAC GGCGGCCTAC CTCCACACCA CAACCACCTT 1680
CACCTGβATG TGCAGCCCCT TCCTGGTGAC CCTGATCACC CTCTGGGTGT ACGTβTACCT 1740
GGACCCAAAC AATβTCCTGG ACGCCGAGAA GGCCTTTβTG TCTGTGTCCT TGTTTAATAT 1800
CTTAAGACTT CCCCTCAACA TGCTGCCCCA GTTAATCAGC AACCTGACTC AGGCCAGTGT 1860
GTCTCTGAAA CGGATCCAGC AATTCCTGAG CCAAGAGGAA CTTGACCCCC AGAGTGTGGA 1920
AAGAAAGACC ATCTCCCCAG GCTATGCCAT CACCATACAC AGTGGCACCT TCACCTGGGC 1980
CCAGGACCTG CCCCCCACTC TGCACAGCCT AGACATCCAG βTCCCGAAAG GGGCACTGGT 2040
GGCCGTGGTG GGGCCTβTββ GCTGTGGGAA GTCCTCCCTG GTGTCTGCCC TGCTGGGAβA 2100
GATGGAGAAG CTAGAAGGCA AAGTGCACAT GAAGGGCTCC GTGGCCTATG TGCCCCAGCA 2160
GGCATGGATC CAGAACTGCA CTCTTCAGGA AAACGTGCTT TTCGGCAAAG CCCTGAACCC 2220
CAAGCGCTAC CAGCAGACTC TGGAGGCCTC TGCCTTGCTA GCTGACCTGG AGATGCTGCC 2280
TGGTGGββAT CAGACAGAGA TTGGAβAGAA GββCATTAAC CTGTCTGGGG GCCAGCGGCA 2340
GCGGGTCAGT CTGGCTCβAβ CTβTTTACAβ TGATGCCGAT ATTTTCTTGC TGGATGACCC 2400
ACTGTCCGCG GTβGACTCTC ATGTGGCCAA GCACATCTTT GACCACGTCA TCGGGCCAGA 2460
AGGCGTGCTG GCAGGCAAGA CGCGAβTGCT GGTGACGCAC GGCATTAGCT TCCTGCCCCA 2520
GACAGACTTC ATCATTGTβC TAβCTβATβG ACAGGTGTCT GAGATGGGCC CGTACCCAGC 2580
CCTGCTGCAG CGCAACββCT CCTTTGCCAA CTTTCTCTGC AACTATGCCC CCGATGAGGA 2640
CCAAGGGCAC CTGGAGGACA GCTGGACCGC GTTGGAAGGT GCAGAGGATA AGGAβGCACT 2700
GCTGATTGAA GACACACTCA GCAACCACAC βGATCTGACA GACAATGATC CAGTCACCTA 2760
TGTGGTCCAG AAGCAGTTTA TGAGACAGCT GAGTGCCCTG TCCTCAGATG GGGAGGGACA 2820
GGGTCGGCCT GTACCCCGβA GGCACCTβGG TCCATCAβAG AAGGTGCAGG TGACAGAGGC 2880
GAAGGCAGAT GGGGCACTGA CCCAGGAββA βAAAGCAβCC ATTGGCACTG TGGAGCTCAG 2940
TGTGTTCTβG GATTATGCCA AGGCCGTGGG GCTCTGTACC ACGCTGβCCA TCTGTCTCCT 3000
GTATGTGGGT CAAAβTGCGG CTGCCATTGG AGCCAATGTG TGGCTCAβTG CCTGGACAAA 3060
TGATGCCATG βCAGACAGTA GACAGAACAA CACTTCCCTG AGGCTGGGCG TCTATGCTGC 3120
TTTAGGAATT CTGCAAGβGT TCTTGGTGAT GCTGGCAGCC ATGGCCATGG CAGCGGGTGG 3180
CATCCAGGCT GCCCGTGTGT TβCACCAGGC ACTGCTGCAC AACAAGATAC GCTCGCCACA 3240
GTCCTTCTTT GACACCACAC CATCAGβCCG CATCCTGAAC TGCTTCTCCA AGGACATCTA 3300
TβTCβTTβAT GAGGTTCTGG CCCCTGTCAT CCTCATGCTG CTCAATTCCT TCTTCAACGC 3360
CATCTCCACT CTTGTGGTCA TCATGGCCAG CACGCCGCTC TTCACTGTGG TCATCCTGCC 3420
CCTGGCTCTβ CTCTACACCT TAGTGCAGCG CTTCTATGCA GCCACATCAC GGCAACTGAA 3480
GCGGCTGGAA TCAGTCAβCC GCTCACCTAT CTACTCCCAC TTTTCGβAGA CAGTGACTGG 3540
TGCCAGTGTC ATCCGGGCCT ACAACCGCAG CCGGGATTTT GAβATCATCA GTGATACTAA 3600 βGTGGATGCC AACCAGAGAA GCTGCTACCC CTACATCATC TCCAACCGGT GGCTGAβCAT 3660
CGGAGTGGAG TTCGTβGGGA ACTGCGTGβT βCTCTTTGCT GCACTATTTG CCGTCATCGG 3720
GAGGAGCAGC CTGAACCCGG GGCTGGTβGG CCTTTCTGTG TCCTACTCCT TGCAGGTGAC 3780
ATTTGCTCTG AACTGGATGA TACGAATGAT GTCAGATTTG GAATCTAACA TCβTββCTCT 3840
GGAβAβGGTC AAGGAGTACT CCAAGACAGA GACAGAGGCG CCCTGGGTGG TGGAAGGGAG 3900
CCGCCCTCCC GAAGβTTGGC CCCCACGTGG GGAGGTGGAG TTCCGGAATT ATTCTGTGCG 3960
CTACCGGCCG βGCCTAGACC TβGTGCTGAG AGACCTGAGT CTGCATGTGC ACGGTGGCGA 4020
GAAGGTGGGG ATCGTGGGCC GCACTGGGGC TGGCAAGTCT TCCATGACCC TTTGCCTGTT 4080
CCGCATCCTG GAGGCGGCAA AGGGTGAAAT CCGCATTGAT GGCCTCAATG TGβCAGACAT 4140
CGCCCTCCAT GACCTGCGCT CTCAGCTGAC CATCATCCCG CAGGACCCCA TCCTGTTCTG 4200
GGGGACCCTC CGCATGAACC TGGACCCCTT CGGCAGCTAC TCAGAGGAGβ ACATTTGGTG 4260 βGCTTTCβAβ CTGTCCCACC TGCACACGTT TGTGAGCTCC CAGCCGGCAG GCCTGGACTT 4320
CCAGTGCTCA GAGGGCGGGG AGAATCTCAG CGTGGGCCAG AGGCAGCTCG TGTGCCTGGC 4380
CCGAGCCCTG CTCCGCAAGA GCCGCATCCT GGTTTTAGAC GAGGCCACAG CTGCCATCGA 4440
CCTGGAGACT GACAACCTCA TCCAGGCTAC CATCCCCACC CAGTTTGATA CCTGCACTGT 4500
CCTGACCATC GCACACCGGC TTAACACTAT CATG6ACTAC ACCAGGGTCC TGGTCCTGGA 4560 CAAAGGAGTA GTAGCTGAAT TTGATTCTCC AGCCAACCTC ATTGCAGCTA GAGGCATCTT 4620 CTACGβGATG GCCAGAGATG CTGGACTTβC CTAAAATATA TTCCTGAGAT TTCCTCCTGG 4680 CCTTTCCTGG TTTTCATCAG GAAGGAAATG ACACCAAATA TGTCCGCAGA ATGGACTTCA 4740 TAGCAAACAC TGGGββCACC TTAAGATTTT GCACCTβTAA AGTGCCTTAC AGGGTAACTG 4800 TGCTGAATGC TTTAGATGAG GAAATGATCC CCAAGTGGTG AATGACACGC CTAAβGTCAC 4860 AGCTAGTTTG AGCCAGTTAG ACTAGTCCCC CGGTCTCCCG ATTCCCAACT GAGTGTTATT 4920 TGCACACTGC ACTGTTTTCA AATAACGATT TTATGAAATG ACCTCTGTCC TCCCTCTCAT 4980 TTTTCATATT TTCCTAAAGT TTCGTTTCTG TTTTTTAATA AAAAGCTTTT TCCTCCTGGA 5040 ACAGAAGACA GCTGCTGGβT CAGGCCACCC CTAGGAACTC AGTCCTGTAC TCTGGGGTGC 5100 TGCCTGAATC CATTAAAAAT GGGAGTACTG ATGAAATAAA ACTACATGGT CAACAGTAAA 5160 AAAAAAAAAA AAAAAA 5176
Seq ID NO: C180 DNA Sequence Nucleic Acid Accession ff: NM.004626 Coding sequence: 124..1188
1 11 21 31 41 51 1 1 | 1 | 1 | 1 | 1 | 1 TAACCCGCCG CCTCCGCTCT CCCCGGCTGC AGGCGGCGTG CAGGACCAGC GGCGβCCβTG 60
CAGGCGGAGG ACTTCGGCGC GGCTCCTCCT GGGTGTGACC CCGGGCGCGC CCGCCGCGCG 120
ACGATGAGGG CGCGGCCCCA CGTCTGCGAG GCGCTGCTCT TCGCCCTGGC GCTCCAGACC 180
GGCGTGTGCT ATGβCATCAA GTGGCTGGCG CTGTCCAAGA CACCATCGGC CCTGGCACTG 240
AACCAGAGGC AACACTGCAA GCAβCTGGAG GGTCTGGTGT CTGCACAGGT GCAGCTGTGC 300
CeCAGCAACC TβGAGCTCAT GCACACGGTG GTβCACGCCG CCCGCGAGGT CATGAAGGCC 360
TGTCGCCGGG CCTTTGCCGA CATGCGCTGG AACTGCTCCT CCATTGAGCT CGCCCCCAAC 420
TATTTGCTTG ACCTββAβAG AGGGACCCGG GAGTCGGCCT TCGTGTATGC GCTGTCGGCC 480
GCCGCCATCA GCCACβCCAT CGCCCGGGCC TGCACCTCCG GCGACCTGCC CGGCTGCTCC 540
TGCGβCCCCG TCCCAGGTGA GCCACCCGGG CCCGGGAACC GCTGGGGAGG ATGTCCGGAC 600
AACCTCAGCT ACGGGCTCCT CATGGGGGCC AAGTTTTCCG ATGCTCCTAT GAAGCTβAAA 660
AAAACAGGAT CCCAAGCCAA TAAACTGATG CGTCTACACA ACAGTGAAβT eeeβAβACAβ 720
GCTCTβCβCG CCTCTCTGGA AATGAAGTGT AAGTGCCATG GGGTβTCTGG CTCCTβCTCC 780
ATCCGCACCT GCTGGAAGGG GCTGCAGGAG CTGCAGGATG TGGCTCCTGA CCTCAAGACC 840
CGATACCTGT CGGCCACCAA GGTAGTGCAC CGACCCATGG GCACCCGCAA GCACCTCGTG 900
CCCAAGGACC TGGATATCCG GCCTGTGAAG GACTCGGAAC TCGTCTATCT GCAGAβCTCA 960
CCTGACTTCT GCATGAAGAA TGAGAAGGTG GGCTCCCACG GGACACAAGA CAGGCAGTGC 1020
AACAAGACAT CCAACGGAAG CGACAGCTGC GACCTTATβT GCTGCGβGCG TββCTACAAC 1080
CCCTACACAG ACCGC6TCGT CGAβCGβTGC CACTGTAAGT ACCACTGGTG CTGCTACGTC 1140
ACCTGCCGCA GGTGTβAGCG TACCGTGGAG CGCTATGTCT GCAAGTGAGG CCCTGCCCTC 1200
CGCCCCACGC AGGAGCGAGG ACTCTGCTCA AGGACCCTCA GCAACTGGGG CCAGGGGCCT 1260
GGAGACACTC CATGGAGCTC TGCTTGTGAA TTCCAGATGC CAGGCATGGβ AGβCGGCTTG 1320
TGCTTTGCCT TCACTTGGAA GCCACCAGGA ACAGAAββTC TGGCCACCCT GGAAGGAGGG 1380
CAGGACATCA AAGGAAACCG ACAAGATTAA AAATAACTTβ βCAGCCTGAG GCTCTGGAGT 1440
GCCCACAGGC TGGTGTAAGG AGCβGGGCTT βGGATCGGTG AGACTGATAC AGACTTGACC 1500
TTTCAGGGCC ACAβAβACCA GCCTCCGββA AGGGGTCTGC CCGCCTTCTT CAGAATGTTC 1560
TGCGGGACCC CCTGGCCCAC CCTGGGGTCT GAGCCTGCTG GGCCCACCAC ATGGAATCAC 1620
TAGCTTGGGT TβTAAATCTT TTCTTTTGTT TTTTGCTTTT TCTTCCTTTG GβATGTGGAA 1680
GCTACAGAAA TATTTATAAA ACATAGCTTT TTCTTTβGGG TGGCACTTCT CAATTCCTCT 1740
TTATATATTT TATATATATA AATATATATβ TATATATATA ATGATCTCTA TTTTAAAACT 1800
AGCTTTTTAA GCAGCTGTAT GAAATAAATG CTGAGTGAGC CCCAGCCCGC CCCTGCAGTT 1860
CCCGGCCTCG TCAAGTGAAC TCGGCAGACC CTGGGGCTGG CAGAGGGAGC TCTCCAGTTT 1920
CCAGGCA 1927
Seq ID NO: C181 DNA Sequence Nucleic Acid Accession #: NM_031866 Coding sequence: 6..2090
60
120
Figure imgf001314_0001
180
ACGACACGCA AGACGAGGCβ GGCCTGGAGG TGCACCAGTT CTGGCCGCTG GTGGAGATCC 240
AGTGCTCCCC CGATCTCAAG TTCTTCCTGT GCAGCATGTA CACGCCCATC TGCCTAGAGG 300
ACTACAAGAA GCCGCTGCCG CCGTGCCGCT CGGTGTGCGA GCGCGCCAAG GCCGGCTGCG 360
CGCCGCTCAT GCβCCAGTAC GGCTTCGCCT GGCCCGACCG CATGCβCTGC GACCββCTβC 420
CCGAGCAAGG CAACCCTGAC ACGCTGTGCA TGGACTACAA CCGCACCGAC CTAACCACCG 480
CCGCGCCCAG CCCGCCGCGC CGCCTGCCGC CGCCGCCGCC CGGCGAGCAG CCGCCTTCGG 540
GCAGCGGCCA CGGCCGCCCG CCGGGGGCCA GGCCCCCGCA CCGCGGAGGC GGCAGGGGCG 600
GTGGCβeceβ GGACGCGGCG GCGCCCCCAG CTCGCGGCGG CGGCGGTGGC GGGAAGGCGC 660
GGCCCCCTGG CGGCGGCGCG GCTCCCTGCG AGCCCGGβTG CCAGTGCCGC GCGCCTATGG 720
TGAGCGTGTC CAGCGAGCGC CACCCGCTCT ACAACCGCGT CAAGACAGGC CAGATCGCTA 780
ACTGCGCβCT GCCCTβCCAC AACCCCTTTT TCAGCCAGGA CGAβCGCGCC TTCACCGTCT 840
TCTGGATCGG CCTβTCβTCG GTGCTCTβCT TCGTGTCCAC CTTCGCCACC GTCTCCACCT 900
TCCTTATCGA CATGGAGCGC TTCAAGTACC CGGAGCGGCC CATTATCTTC CTCTCGGCCT 960
GCTACCTCTT CGTGTCGGTG GGCTACCTAG TGCGCCTGGT GGCGGGCCAC GAGAAGGTGG 1020
CGTGCAGCGG TGGCGCGCCG GGCGCGGGGG GCGCTGGGGG CGCGGGCGGC GCGGCGGCGG 1080
GCβCGGGCGC GGCGGGCGCG GGCGCGGGCβ GCCCGβGCGβ βCβCGGCGAG TACGAGGAGC 1140
TGGGCGCGGT GβAβCAGCAC GTGCGCTACG AGACCACCGG CCCCGCGCTG TGCACCGTGG 1200
TCTTCTTGCT GGTCTACTTC TTCGGCATGβ CCAGCTCCAT CTGGTGGGTG ATCTTGTCGC 1260
TCACATGGTT CCTGGCGGCC GGTATGAAGT GGGGCAACGA AGCCATCGCC GβCTACT∞C 1320
AGTACTTCCA CCTββCCGCG TGGCTTGTGC CCAGCGTCAA GTCCATCGCG GTGCTGGCβC 1380
TCAGCTCGGT GGACGβCGAC CCGGTGβCGG GCATCTGCTA CGTGGGCAAC CAGAGCCTGG 1440
ACAACCTGCG CGGCTTCGTG CTGGCGCCGC TGGTCATCTA CCTCTTCATC GGCACCATGT 1500
TCCTGCTβGC CGGCTTCGTG TCCCTGTTCC GCATCCGCTC GGTCATCAAβ CAACAGGACG 1560
GCCCCACCAA GACGCACAAG CTGGAGAAGC TGATGATCCG CCTGGGCCTG TTCACCGTGC 1620
TCTACACCGT GCCCGCCGCG GTGGTGGTCG CCTGCCTCTT CTACGAGCAG CACAACCGCC 1680
CGCGCTGGGA GGCCACGCAC AACTGCCCGT GCCTGCG6GA CCTGCAGCCC GACCAGGCAC 1740
GCAGGCCCCA CTACGCCGTC TTCATGCTCA AGTACTTCAT βTCCCTACTG GTββGCATCA 1800
CCTCGGGCGT GTGGGTCTGG TCCGGCAAGA CGCTGGAGTC CTGGCGCTCC CTGTGCACCC 1860
GCTGCTGCTG GGCCAGCAAG GβCGCCGCGG TGGGCGGGGG CGCGGGCGCC ACGGCCGCGG 1920
GGGGTGGCGG CGGGCCGGGG GGCGGCGGCG GCGGGGGACC CGGCGGCGGC G6GGGGCCGG 1980
GCGGCGGCGG GGGCTCCCTC TACAGCGACG TCAGCACTGG CCTGACGTGG CGGTCGGGCA 2040
CGGCGAGCTC CGTGTCTTAT CCAAAGCAGA TGCCATTGTC CCAGGTCTCA GCGGAGGGGA 2100
GGGGGCGCCC AGGAGβGGTG GGGAGGGGGG CGAGGAGACC CAAGTGCAGC GAAGGGACAC 2160
TTGATGGGCT GAβGTTCCCA CCCCTTCACA GTGTTβATTG CTATTA6CAT GATAATGAAC 2220
TCTTAATGGT ATCCATTAGC TGGGACTTAA ATGACTCACT TAGAACAAAG TACCTGGCAT 2280
TGAAGCCTCC CAGACCCAGC CCCTTTTCCT CCATTGATGT GCGGGGAGCT CCTCCCGCCA 2340 CGCGTTAATT TCTGTTGGCT GAββAβββTG GACTCTGCGG CGTTTCCAGA ACCCGAGATT 2400
TGβAGCCCTC CCTGGCTGCA CTTGGCTGGG TTTGCAGTCA GATACACAGA TTTCACCTGG 2460
GAGAACCTCT TTTTCTCCCT CGACTCTTCC TACGTAAACT CCCACCCCTG ACTTACCCTG 2520
GAGGAGGGGT GACCGCCACC TGATGGGATT GCACGGTTTG GGTATTCTTA ATGACCAGGC 2580
AAATGCCTTA AGTAAACAAA CAAGAAATGT CTTAATTATA CACCCCACGT AAATACGGGT 2640
TTCTTACATT AGAGGATGTA TTTATATAAT TATTTGTTAA ATTGTAAAAA AAAAAAGTGT 2700
AAAATATGTA TATATCCAAA GATATAGTGT GTACATTTTT TTGTAAAAAG TTTAGAGGCT 2760
TACCCCTGTA AGAACAGATA TAAGTATTCT ATTTTGTCAA TAAAATGACT TTTGATAAAT 2820 βATTTAACCA TTGCCCTCTC CCCCGCCTCT TCTGAGCTGT CACCTTTAAA GTGCTTGCTA 2880
AGGACGCATG GGGAAAATGG ACATTTTCTG GCTTGTCATT CTGTACACTG ACCTTAGGCA 2940
TGGAGAAAAT TACTTGTTAA ACTCTAGTTC TTAAGTTGTT AGCCAAGTAA ATATCATTGT 3000
TGAACTGAAA TCAAAATTGA GTTTTTβCAC CTTCCCCAAA GACGGTGTTT TTCATGGGAG 3060
CTCTTTTCTG ATCCATGGAT AACAACTCTC ACTTTAGTGG ATGTAAATGG AACTTCTGCA 3120
AGGCAGTAAT TCCCCTTAGG CCTTGTTATT TATCCTGCAT GGTATCACTA AAGβTTTCAA 3180
AACCCTGAAA AAAAA 3195
Seq ID NO: C182 DNA Sequence Nucleic Acid Accession ff: XM_050625 Coding sequence: 222..1109
1 11 21 31 41 51
I I I I I I
CCGGGTCGGA GCCCCCCGGA GCTCCGCGCG GGCTTGCAGC GCCTCGCCCG CGCTGTCCTC 60
CCGGTGTCCC GCTTCTCCGC GCCCCAGCCG CCGGCTGCCA GCTTTTCGGG GCCCCGAGTC 120
GCACCCAGCG AAGAGAGCGG GCCCGGGACA AGCTCGAACT CCGGCCGCCT CGCCCTTCCC 180
CGGCTCCGCT CCCTCTGCCC CCTCGGGGTC GCGCGCCCAC GATGCTGCAG GGCCCTGGCT 240
CGCTGCTGCT GCTCTTCCTC GCCTCGCACT GCTGCCTGGG CTCGGCGCGC GGGCTCTTCC 300
TCTTTGGCCA GCCCGACTTC TCCTACAAGC GCAGCAATTG CAAGCCCATC CCTGCCAACC 360
TGCAGCTGTC CCACGGCATC GAATACCAGA ACATGCGGCT GCCCAACCTG CTGGGCCACG 420
AGACCATCAA GGAGGTGCTG GAGCAGGCCG βCGCTTGGAT CCCβCTCβTC ATβAAGCAGT 480
GCCACCCGGA CACCAAGAAG TTCCTGTGCT CGCTCTTCGC CCCCGTCTGC CTCGATGACC 540
TAGACGAGAC CATCCAGCCA TGCCACTCGC TCTGCGTGCA GGTGAAGβAC CGCTGCGCCC 600
CGGTCATGTC CGCCTTCGGC TTCCCCTGGC CCGACATGCT TGAGTGCGAC CGTTTCCCCC 660
AGGACAACGA CCTTTGCATC CCCCTCGCTA GCAGCGACCA CCTCCTGCCA GCCACCGAGG 720
AAGCTCCAAA GGTATGTGAA GCCTGCAAAA ATAAAAATGA TGATGACAAC GACATAATGG 780
AAACGCTTTG TAAAAATGAT TTTCCACTCA AAATAAAAGT GAAGGAGATA ACCTACATCA 840
ACCGAGATAC CAAAATCATC CTGGAβACCA AβAGCAAGAC CATTTACAAG CTGAACGGTG 900
TGTCCGAAAG GGACCTGAAG AAATCGGTGC TGTGGCTCAA AGACAGCTTG CAGTGCACCT 960
GTGAGGAGAT GAACGACATC AACGCβCCCT ATCTGGTCAT GGGACAGAAA CAGGGTGGGG 1020
AGCTGGTGAT CACCTCGGTG AAGCGβTGGC AGAAGGGGCA GAGAGAGTTC AAGCGCATCT 1080
CCCGCAGCAT CCGCAAGCTG CAGTGCTAGT CCCGGCATCC TGATGGCTCC GACAGGCCTG 1140
CTCCAGAGCA CGGCTGACCA TTTCTGCTCC βGGATCTCAG CTCCCGTTCC CCAAGCACAC 1200
TCCTAGCTGC TCCAβTCTCA GCCTGGGCAG CTTCCCCCTG CCTTTTGCAC GTTTGCATCC 1260
CCAGCATTTC CTGAGTTATA AGGCCACAGG AGTGGATAGC TGTTTTCACC TAAAGGAAAA 1320 GCCCACCCGA ATCTTGTAGA AATATTCAAA CTAATAAAAT CATGAATATT TTTATGAAβT 1380 TT 1382
Seq ID NO: C183 DNA Sequence Nucleic Acid Accession ft: NM_001306.1 Coding sequence: 199..861
1 11 21 31 41 51
I I I I I I
AATTCGGCAC GAGGGCAGGT GCAGGCGCAC GCGGCGAGAG CGTATGGAGC CGAGCCGTTA 60
GCGCCCGCCG TCGGTGAGTC AGTCCGTCCG TCCGTCCGTC CGTCGGGGCG CCGCAGCTCC 120
CGCCAGGCCC AGCGGCCCCG GCCCCTCGTC TCCCCGCACC CGGAGCCACC CGGTGGAGCG 180
GGCCTTGCCG CGGCAGCCAT GTCCATGGGC CTGGAGATCA CGGGCACCGC GCTGGCCGTG 240
CTGGGCTGGC TGGGCACCAT CGTGTGCTGC GCGTTGCCCA TGTGGCGCGT GTCGGCCTTC 300
ATCGGCAGCA ACATCATCAC GTGGCAGAAC ATCTGGGAGG GCCTGTGGAT GAACTGCGTG 360
GTGCAGAGCA CCGGCCAGAT GCAGTGCAAG GTGTACGACT CGCTGCTGGC ACTGCCACAG 420
GACCTTCAGG CGGCCCGCGC CCTCATCGTG GTGGCCATCC TGCTGGCCGC CTTCGGGCTG 480
CTAGTGGCGC TGGTGGGCGC CCAGTGCACC AACTGCGTGC AGGACGACAC GGCCAAGGCC 540
AAGATCACCA TCGTGGCAGG CGTGCTGTTC CTTCTCGCCG CCCTGCTCAC CCTCGTGCCG 600
GTGTCCTGGT CGGCCAACAC CATTATCCGβ GACTTCTACA ACCCCGTGGT GCCCGAGGCG 660
CAGAAGCGCG AGATCGGCGC GGGCCTGTAC GTGGβCTGGG CGGCCGCGβC GCTGCAGCTG 720
CTGGGGGGCG CGCTGCTCTG CTGCTCGTGT CCCCCACGCG AGAAGAAGTA CACGGCCACC 780
AAGGTCGTCT ACTCCGCGCC GCGCTCCACC GGCCCGGGAG CCAGCCTGGG CACAGGCTAC 840 βACCGCAAGG ACTACGTCTA AGGGACAGAC GCAGGGAGAC CCCACCACCA CCACCACCAC 900
CAACACCACC ACCACCACCG CGAGCTGGAG CGCGCACCAG GCCATCCAGC GTGCAGCCTT 960
GCCTCGGAGG CCAGCCCACC CCCAGAAGCC AGGAAGCCCC CGCGCTGGAC TGGGGCAGCT 1020.
TCCCCAGCAG CCACGGCTTT GCGGGCCGGβ CAGTCGACTT CGGGGCCCAG GGACCAACCT 1080
GCATGGACTG TGAAACCTCA CCCTTCTGGA GCACGGGGCC TGGGTGACCG CCAATACTTG 1140
ACCACCCCβT CGAGCCCCAT CββGCCGCTG CCCCCAT6TC GCGCTGGGCA GGGACCGGCA 1200 βCCCTGGAAβ GGGCACTTGA TATTTTTCAA TAAAAGCCTC TCGTTTTAGC 1250
Seq ID NO: C184 DNA Sequence
Nucleic Acid Accession ff: NM_012449.1
Coding sequence: 66..1085
1 11 21 31 41 51
I I I I I I
CCGAGACTCA CGGTCAAGCT AAGGCGAAGA GTGGGTGGCT GAAGCCATAC TATTTTATAG 60
AATTAATGGA AAGCAGAAAA GACATCACAA ACCAAGAAGA ACTTTGGAAA ATGAAGCCTA 120
GGAGAAATTT AGAAGAAGAG GATTATTTGC ATAAGGACAC GGGAGAGACC AβCATGCTAA 180 AAAGACCTGT GCTTTTGCAT TTGCACCAAA CAGCCCATCC TGATGAATTT GACTGCCCTT 240
CAGAACTTCA GCACACACAG GAACTCTTTC CACAGTGGCA CTTGCCAATT AAAATAGCTG 300
CTATTATAGC ATCTGTGACT TTTCTTTACA CTCTTCTβAG GGAAGTAATT CACCCTTTAG 360
CAACTTCCCA TCAACAATAT TTTTATAAAA TTCCAATCCT GGTCATCAAC AAAGTCTTGC 420
CAATGGTTTC CATCACTCTC TTGGCATTGG TTTACCTGCC AGGTGTGATA GCAGCAATTG 480
TCCAACTTCA TAATGGAACC AAGTATAAGA AGTTTCCACA TTGGTTGGAT AAGTGGATGT 540
TAACAAGAAA GCAGTTTGGG CTTCTCAGTT TCTTTTTTGC TGTACTGCAT GCAATTTATA 600
GTCTGTCTTA CCCAATGAGG CGATCCTACA GATACAAGTT GCTAAACTGG GCATATCAAC 660
AGGTCCAACA AAATAAAGAA GATGCCTGGA TTGAGCATGA TGTTTGβAβA ATGGAGATTT 720
ATGTGTCTCT GGGAATTGTβ GGATTGGCAA TACTGGCTGT GTTGGCTGTG ACATCTATTC 780
CATCTGTGAG TGACTCTTTG ACATGGAGAG AATTTCACTA TATTCAGAGC AAGCTAGGAA 840
TTGTTTCCCT TCTACTGGGC ACAATACACG CATTGATTTT TCCCTGGAAT AAGTGGATAG 900
ATATAAAACA ATTTGTATGG TATACACCTC CAACTTTTAT GATAGCTCTT TTCCTTCCAA 960
TTGTTGTCCT GATATTTAAA A6CATACTAT TCCTGCCATG CTTGAβGAAG AAGATACTGA 1020
AGATTAGACA TGGTTGGGAA βACGTCACCA AAATTAACAA AACTGAGATA TGTTCCCAGT 1080
TGTAGAATTA CTGTTTACAC ACATTTTTGT TCAATATTGA TATATTTTAT CACCAACATT 1140
TCAAGTTTGT ATTTGTTAAT AAAATGATTA TTCAAGGAAA AAAAAAAAAA AAAAA 1195
Seq ID NO: C185 DNA Sequence Nucleic Acid Accession # : NM_001775.1
Coding sequence : 70. .972
1 11 21 31 41 51 1 1 | 1 1 1 | 1 | 1 | 1 CTAAAGCTCT CTTGCTGCCT AGCCTCCTGC CGGCCTCATC TTCGCCCAGC CAACCCCGCC 60
TββAGCCCTA TGGCCAACTG CGAGTTCAGC CCGGTGTCCG GGGACAAACC CTGCTGCCGG 120
CTCTCTAββA GAGCCCAACT CTGTCTTGGC GTCAGTATCC TβGTCCTGAT CCTCGTCGTG 180
GTGCTCGCGG TGGTCGTCCC GAGGTGGCGC CAGACGTGGA GCGGTCCGGG CACCACCAAβ 240
CGCTTTCCCG AGACCGTCCT GGCGCGATGC GTCAAGTACA CTGAAATTCA TCCTGAGATG 300
AGACATGTAG ACTGCCAAAG TGTATGGGAT GCTTTCAAGG GTGCATTTAT TTCAAAACAT 360
CCTTGCAACA TTACTGAAGA AGACTATCAG CCACTAATGA AGTTGGGAAC TCAGACCGTA 420
CCTTGCAACA AGATTCTTCT TTGGAGCAGA ATAAAAGATC TGGCCCATCA GTTCACACAG 480
GTCCAGCGGG ACATGTTCAC CCTGGAGGAC ACGCTGCTAG GCTACCTTGC TGATGACCTC 540
ACATGβTGTG GTGAATTCAA CACTTCCAAA ATAAACTATC AATCTTGCCC AGACTGGAGA 600
AAGGACTGCA GCAACAACCC TGTTTCAGTA TTCTGGAAAA CGGTTTCCCG CAGGTTTGCA 660
GAAGCTGCCT GTGATGTGβT CCATGTGATβ CTCAATGGAT CCCGCAGTAA AATCTTTGAC 720
AAAAACAGCA CTTTTGGGAG TGTGβAACTC CATAATTTGC AACCAGAβAA GGTTCAGACA 780
CTAGAGGCCT GGGTGATACA TGGTβGAAGA GAAGATTCCA βAβACTTATG CCAGGATCCC 840
ACCATAAAAβ AGCTGGAATC GATTATAAGC AAAAGGAATA TTCAATTTTC CTGCAAGAAT 900
ATCTACAGAC CTGACAAGTT TCTTCAGTGT GTGAAAAATC CTGAGβATTC ATCTTGCACA 960
TCTGAGATCT GAGCCAGTCG CTGTC6TTCT TTTAGCTCCT TCACTCCTTC TGGTTTATGT 1020
CATCATACAT GACTCAGCAT ACCTβCTββT GCACAGCTGA AGATTTTGGA GGGTCCTCCA 1080
CAATAAGGTC AATGCCAGAG ACGβAAGCCT TTTTCCCCAA AGTCTTAAAA TAACTTATAT 1140
CATCAGCATA CCTTTATTGT βATCTATCAA TAGTCAA6AA AAATTATTGT ATAAGATTAG 1200
AATGAAAATT GTATGTTAAG TTACTTCCTT TAG 1233
Seq ID NO: C186 DNA Sequence
Nucleic Acid Accession ft: XM_120513.2
Coding sequence : 1. .2208
1 11 21 31 41 51 1 1 11 ] 1 | 1 | 1 | 1 ATGGTGTCAT GCACGTTCTC GGGGCCCCTA CGGGAAACAA ATGAAAACGT GAAAAAGTTC 60
TACGCCTTGC GAGCTTTTAT GTTCCGCATG AGCTCACAGG CCGCGATGCT CGGGGAAAGC 120
AGGACCCCAA AGCCCCGTAA ACACCGCGCG ACCACCCGGG CCAAGATCTT CAAGAGGTTC 180
TTTTCAGAAG GATCGGAGAG CAATTCCCGA TTGGTAGAAβ AACTTGCTGT AATACACACG 240
TACTCTGACG ACCCCGCCCC AACGACTAGC CCCTCCTCTG TGCAACCCCG AGAGTTTGGG 300
GTCATGCAGG GGGCGCCACG AGCTCGTTTC GGAAGCCGGA CCCCGCCCGC AGCCGCAGAA 360
GCCTCGAGTC CACATCTGGG CATTGGCGAG GCAGCCTGTC AATCAGGAGC TCGGGCGGCA 420
GCCCCCCGCG CGGGGGCTCG GCGATGCCAG CCTCAGCβAC AGGCGGCGGC GGCβeceecc 480
ACGGCACAGA CACACACCCT CCCACACGCG CGCACCAGGG CAGACCCGGC GGGCAGGCGG 540
CGGAGGCACC CTCGGAGCCC GGCGCCCGGC GGGGAGGGGA CGTGCTCCGA GGGACCGGCC 600
CCGAGGCβCC GGATGGAGGA AGAGATGCAG CCGGCAGAGG AGGGGCCCAG CGTCCCCAAA 660
ATCTACAAGC AGCGCAGCCC CTACAGCGTC CTCAAGACGT TCCCCAGCAA GAGACCGGCG 720
CTGGCCAAβC GCTACGAGCG ACCCACCCTG GTGGAβCTGC CGCACGGCCA CTTGAβGACT 780
CCGGCGCAGC CGCCGCCCGC GTCCCCCGCC GCCTCCTCGT CGTCTTCGTT CGCCβCTGTC 840
GTCAGACTCβ GGGCTCCTCC GCGTCCGCCA CGCCGTGGAT TTCGGGCGCG GGGAACCATC 900
CCGCCCCTCC TTCCTGCCCC GGGAβTCGCA GGCACTCTGC TCCCACCGCC CACGTCGTCG 960
TCCCCGCCAT CCCCTCGTCC CCGTCCGTGG CACGCTGCCG CGCCGCGGGG AGββACCTCA 1020
CATACACATA TGTGGAGGTC CCAGTCCACA CTTCCAGGAT CTGACACCAT GGTCTCTGTC 1080
TTTGGATTGA TGGCTCAGAG AAGATGGCAG CATAGATCTT TAAAGCAGTT TGAGTGGGGA 1140
ATTCTTGGAT CTTGGGGTAC TTGβCCATβT GβACAGGATT GGCTGGAGAA GGAGGGTCAG 1200
GTGGCGGTCC TGCTGCCAAG GTCTGAGGGT AATACTGCTC CTAAGAAGAG TCGAATGATC 1260
TTGGATGCCT TTGCCCAGCA GTβCAGTCGA GTTCTTAGCC TCTTAAATTG TGGAGGAAAA 1320
CTCCTGGACT CCAACCATTC TCAGTCCATG ATTTCTTGCβ TAAAGCAGGA AGGCTCAAGT 1380
TACAACGAAA GACAGGAGCA CTGTCACATT GGGAAAGGGβ TCCACAGTCA GACCTCAGAC 1440
AATGTAGACA TAGAGATGCA GTATATCCAA AGGAAACAAC AAACTTCTGC CTTTTTGAGG 1500
GTTTTCACTG ACTCTCTACA AAATTACCTβ CTCTCGGGAA GCTTTCCAAC TCCAAACCCC 1560
TCGTCAGCCA GTGAATATGG CCATCTGGCC GACGTGGATC CTCTGTCAAC CTCTCCTGTβ 1620
CATACATTAG AAAATATTTC ACTTGATTCC ACAGCTTCCC TGTGTAAATC TAβGCATCTA 1680
TCCAGAGAGC CCCCAGTCAA GAβTGATTTT CCAAATCCTT TGCAGCAGGC CTTGGCTGGG 1740
GGTGCTTCAA GACCATTTTC AGGGGCACAG CAAAGCATCG CTTACAGGGT GAACTCTGAA 1800
CTTGAGGATβ GCATCCGCAG CCCCGTCCCT TTGAGTTGTG AGGCCTTGGA AATGGATTTG 1860
ACCTCCTTGG GAAGCAAGCA GCTGTTGAAC AACTATCCTβ TCTACATAAC GAGCAAACAG 1920 TGβGATGAGG CTGTAAATTC TTCAAAGAAA GATGGGAGAC GGCTCCTTCG ATACCTCATC 1980
AGATTTGTTT TCACAACCGA TGAβCTTAAG TACTCATGCG GCCTTGGGAA AAGGAAAAGG 2040
TCAGTGCAGT CAGGAGAGAC AGβTCCCGAA AGACGCCCTC TGGATCCAGT TAAAGTAACA 2100
TGCCTCCGAG GTACTCCATC CTTCCGCTCA GTGTCACCAT CTGTGATCTC ATTTCACCGC 2160
ATTGGCTGTG GCTCTCCCCβ TACAAGTGTT CAGCCTTCTG TATTTTGA 2208
Seq ID NO: C187 DNA Sequence Nucleic Acid Accession ft: AB037745.1 Coding sequence: 26..1744
11 21 31 41 51
ATGGTGGAAC ACGCTGCCCA CAAACATGGA AACGACCβTT CTCAGTGGGA TCAACTTCGA 60
GTACAAGGGC ATGACAGGCT GGGAGGTGGC TGCTGATCAC ATTTACACAC CTβCTGGAGC 120
CTCAGACAAT GACTTCATGA TTCTCACTCT GGTTGTGCCA GGATTTAGAC CTCCGCAGTC 180
GGTGATGGCA GACACAGAGA ATAAAGAGGT GGCCAGAATC ACATTTGTCT TTGAGACCCT 240
CTGTTCTGTG AACTGTCAGC TCTACTTCAT GGTGβGTGTG AATTCTAGGA CCAACACTCC 300
TGTGGAGACG TGGAAAGGTT CCAAAGGCAA ACAGTCCTAT ACCTACATCA TTGAGGAGAA 360
CACTACCACG AGCTTCACCT GGGCCTTCCA GAββACCACT TTTCATGAGG CAAGCAGGAA 420
GTACACCAAT GACGTTGCCA AGATCTACTC CATCAATGTC ACCAATGTTA TGAATGGCGT 480
GGCCTCCTAC TGCCGTCCCT GTGCCCTAGA AGCCTCTGAT GTGGGCTCCT CCTGCACCTC 540
TTGTCCTGCT GβTTACTATA TTGACCGAGA TTCAGβAACC TGCCACTCCT GCCCCCCTAA 600
CACAATTCTG AAAGGCCACC AGCCTTATGG TβTCCAGGCC TGTGTGCCCT GTGGTCCAGG 660
GACCAAGAAC AACAAGATCC ACTCTCTGTG GTACAATGAT TGCACCTTCT CACGCAACAC 720
TCCAACCAGG ACTTTCAACT ACAACTTCTC CGCTTTGGCA AACACCGTCA CTCTTGCTGG 780
AGGGCCAAGC TTCACTTCCA AAGGGTTGAA ATACTTCCAT CACTTTACCC TCAGTCTCTG 840
TGGAAACCAG GGTAGGAAAA TGTCTGTGTG CACCGACAAT GTCACTGACC TCCGGATTCC 900
TGAGGGTGAG TCAGGGTTCT CCAAATCTAT CACAGCCTAC GTCTGCCAGG CAGTCATCAT 960
CCCCCCAGAG GTGACAGGCT ACAAGGCCGG GGTTTCCTCA CAGCCTGTCA GCCTTGCTGA 1020
TCGACTTATT GGGGTGACAA CAGATATβAC TCTGGATGGA ATCACCTCCC CAGCT6AACT 1080
TTTCCACCTG GAGTCCTTGG GAATACCGβA CGTGATCTTC TTTTATAGGT CCAATGATGT 1140
GACCCAGTCC TGCAGTTCTG GGAGATCAAC CACCATCCGC GTCAGGTGCA GTCCACAGAA 1200
AACTGTCCCT GGAAGTTTGC TGCTGCCAGG AACGTGCTCA GATGGGACCT GTGATGGCTG 1260
CAACTTCCAC TTCCTGTGGG AGAGCGCGβC TGCTTGCCCG CTCTGCTCAG TββCTGACTA 1320
CCATGCTATC GTCAGCAGCT GTGTGGCTGG GATCCAGAAβ ACTACTTACG TGTGβCGAGA 1380
ACCCAAGCTA TGCTCTGGTG βCATTTCTCT GCCTGAGCAG AGAGTCACCA TCTGCAAAAC 1440
CATAGATTTC TGGCTGAAAG TGGGCATCTC TGCAGβCACC TGTACTGCCA TCCTGCTCAC 1500
CGTCTTGACC TGCTACTTTT GGAAAAAGAA TCAAAAACTA GAGTACAAGT ACTCCAAGCT 1560
GGTGATGAAT GCTACTCTCA AGGACTGTGA CCTGCCAGCA GCTGACAGCT GCGCCATCAT 1620
GGAAGGCGAG GATGTAGAβG ACGACCTCAT CTTTACCAGC AAGAAGTCAC TCTTTGGGAA 1680
GATCAAATCA TTTACCTCCA AGCAGCCAGC TCCTGTCACC ATCTCTCTTT CAGAGGACTC 1740
CTGATGGATT TGACTCAGTG CCGCTGAAGA CATCCTCAGβ AGGCCCAGAC ATGGACCTGT 1800
GAGAGGCACT GCCTGCCTCA CCTGCCTCCT CACCTTGCAT AGCACCTTTG CAAGCCTGCG 1860
GCGATTTGGG TGCCAGCATC CTGCAACACC CACTβCTGGA AATCTCTTCA TTβTGGCCTT 1920
ATCAGATGTT TGAATTTCAG ATCTTTTTTT ATAGAGTACC CAAACCCTCC TTTCTGCTTG 1980
CCTCAAACCT GCCAAATATA CCCACACTTT GTTTGTAAAT TATGGCCTTG CTTGTATCTT 2040
GTTTCCCAAA ATGGCCCATC CGCCAGAGCC ATAGCTTCGT CTGCTCATAA TTCTTATAGC 2100
TTTGGAATCA AAATATTTCT ATCTTCTTAA GTATAGAAAC TATTTCCTCT GTCCTCTAAC 2160
TTAAββGCAβ AAACAGCTGG GAGTTTTCCT CGCATGCCCT CAGCTCATGA TCTCTTCAGG 2220
AGAGAGGCTG GβTβAβGAGβ GTGTCGGGGT TCCCTGβTGG ATAATCTTCA TAβCAGCCTG 2280
GATCCATTTC CCCTββATAA CCAGCTCAAA GGGAβTGAAA ATGGTAGTCT GAGGGCAAGG 2340
GGAGCAAGGC CTGGGTAAGA AAAGCCTTGA AAAGCATAAA AAGAGGCCGG GCGCGGTGGC 2400
TCACGCCTGT AATCCCAGCA CTTTGGGAGG CCGAGGCGGG CAβATCATGA GGTCGGGAGA 2460
TTGAGACCAT CCTGGCTAAC ACGGTGAAGC CCCGTCTCTA CTGGAAATAC AAAAAATTAG 2520
CCGGGCGTGG TGβCGGGTβC CTβTGGTCCC AβCTACTCGG GAGGCTGAGG CGGGAGAATA 2580
GCGTGGGCCT GGAAGGCGGA GCTTGCAGTG AGCCGAGATC GCGCCACTGC ACTCCATCCA 2640
GCCTGGGTGA CAGAGTGAGA CTCTGCCTCA AAAAAAAAAA AAAAAAAGAA AAGCACAAAG 2700
AGAGGCAACA AGGAATGTTT TTGTTTTTGA GACA6GCTCT CACTCTGTCA CCTAGGCTGG 2760
AGTβCAGTGβ CGTAATCACT GTTCAGTGCA GCCTCAAGCT CTTGGGCTCA GGCTATCCTC 2820
CCATCTCAGC CTCTCAAGTA GCTGGGACTA CGAGTGTGCA CCACCAGGCT CACTAATTTT 2880
TGTGTTTTTT GTAGACACGG GGTTTCACCG TGTTGCCCAG GCTGGTCTCC AACTCCTGGG 2940
CTCAAGTGAT CTGTCCGCCT CββCCTCCCA AACTGCTGGG ATTACAGGCA TAAGCCACTG 3000
CACTCAGCCT TTTATTTGTT TTTTAAACCA CGTAGCTCAT TGCCTTCTCT TAAGTAAATG 3060
ATAGATATTC TCACTGAAGC CAAAGGAATA AGTTCATCAA GAAAATGCCC AAAGCCCTGG 3120
TGGATACATC CTCCCTATCT TTTTTTTAAA CCTTCCACTA TCACTCTATG ACACTGAAAA 3180
GAACCAGGTA AGCCCCAAAC CCAGATβTTC CAGCCTTATC CTCTATTGGG TTTACCCACA 3240
GACATAGCAA ACCCTGTCAG TGAβGAAAAT TCCCCATCCT TGAGTGCCCC CGTCCTAGAA 3300
GTTTGGGCCA TATTATGGAA CAGGGGTCTC TTATTTGAAA AGAGCACAAG GAGGCCAAGA 3360
TTTTAATGGG GCACTTTAGG GβATACAGCC CACAATGβCA TGGGCCTGAG GTGGCCGTGA 3420
TGTCTGCTTC TAACCTTAAC GCATCTGCTC AGGCACAGAA TAAACGTCTA GGCTGGCCAA 3480
AAAAGGAACT GAATCCCAGG CCCATACGCC AGCACCAGAA TCAAACCAGT CTTCAAGGAA 3540
GGAAGGCTAG GAGAGTTTAA CAAGATTTTC ACTGGGCCCA GCATGGTGGC TCACACCTGT 3600
AATCCCAAGβ CAβAATGGTG GCTTGAGCTC AGGAGTTCAA GACCAGCCTG GβCAACACAβ 3660
TGAGACCCTG TCTCTAAAAA ATTTAAAAAT AAACAAGGTG TTCACCAAGC TGGGATACTT 3720
CTCACTATTA AGCCCCTATC TTTCTCTTTT TTTCATTCTC AATTGCTTTG TGTGATAAAA 3780
AACTAAAGAG ACTTCTGGTC CAATTTCTGG CAACATCCCT TCTGAAAGGT GAGTAGAGTG 3840 βGTGTCTTCT ATGCCCATTT TCCCCAATTT TACACAAACT ATTATCAATG AACTTTTAAG 3900 TACCTAGAAT GββTAAAACC AGAGCAAGAC TTTAAATTAC CTTCTTCTTT CTTCTACTGG 3960 CAGTTCTGCC TCCATCACTA TCAGGCTAGG GTGACCTTCC CTTGGTCAAG CCCCAATTGC 4020 CCATCATTTC TβCCTGTGCC CTTTCTCCAG TGACCATTTG GTGACCAGAT GGTAGATATA 4080 GAAAGGGGAT GGCATTTGCA AGTGACTAGT CTGCCACAAA ATGCTCATCT GATTAGCCAC 4140 TGCTGCCCTG GCAATGGCTT TGTAAGAGTC AATGAGAACT AGAGCCAGGC TGTGGTCCCT 4200 GGCCATCAAC _AGTGTTGGTG ACGGCAGGGA GTCCCTTTGG TTTAATAAAT CCAGTTTTTC 4260 TTTGGGTATC CAAATTCTCC CCTCCTTTTG TAGGAGTCAG GCTCTCAGAA CCTβTβTCCA 4320 TGTTGβAACT TCCCCCAGTβ TGβATGCAGA TACGCAGCTC CTGAGCTCCA GCCTAAAGTC 4380
TTCTGTAGCC TCAGCAATAC TTGGGCACCT GCTGTCTCAC TGAATAGCTT TCTTTTGTGA 4440
CAAAβGCCAC AGACAGCCCT TAGACTATTC CGGAAACAGT AGGAAAAATT ACATATGTCT 4500
TTGACTTCTT TATTCTGACT CCACTGATTT TAGCCATAAT ACTTTAAGGA GCTACTTTTT 4560
ACTACCCCTT ACCGTGCTGA CTTCTGCAGG TCTGCCCTGT GACCTGTCAG GAACTCCTGA 4620
CTTACGCTAC TGGGGTCACC TGTTGCTCCC CTAGCAAGTT AGGCATGTCA TATATTTTTA 4680
ACAGCTTTAT TGAGATATAA TTCACATATT ATACAATTCA CCTTTAAAAC ATACGATTCA 4740
ATGGTTTTCA GCAAACTCAC AGAGTTGTCC GCCCACTTGA GAGCAAACAC ATGTTCAATT 4800
TTCTTTTCCT TTTTTTTTTT GAGACAGAGT CAGCTTTGTC GCCCAGβCTG GAGTGCAGTG 4860
CCATGATCTT GGCTCACTGC AGCCTCCCCA TCCTGGGTTC AAGTGATCCT TCTGCTTCAG 4920
CCTCCCCAGT AβCTGGGATT ACAGβCATGC GCCACCACGC CTAGCTAATT TTTGTGTTTT 4980
TAGTAGAGAT GGGGTTTCAC CGTGTTGGCC AGGCTGGTCT CAAACTCCTG GACTCAAGTG 5040
ATCCACCCAC CTceeccTCC CAAAGTβCTG GGATTGCAGG TGTGAGCCAC CGTβCCTGGC 5100
CTACGTGTTC AATTTTCTAT GAACAAAGGC TTTAGTCCTT GACCCAGGGC TAAAGTGGTC 5160
TGTCCAAGCT βTTβTTGGTA GAGGGAGTAT GATAAAATGT TTAAATCTCA TTTGGTTACC 5220
TTGAGTCCTG GAACACβCAG TAACTGTCAT GCTATAGTCA TCATCTGTAT TTGGCTGGGA 5280
ATACAAATGA AGATTGTGGT GTATTCAAGC ACTAβGGTTT TTGCTTTTGT TTTTGTTTTA 5340
GTGCCAACAA AACTTTTTTT TGTCTGACTA CATTAAAGAT AAGACTGACT ATATTTATAC 5400
AACAGAAACT TTGTAATAGA TTTTTTCAGC TTTGTGAAAT CGAATTTTTT TTCATCAGββ 5460
CTGGTTGGAT TTCCTTTTTA CCCTGTAATC CAAGCGTTAA TAβTTTβTTA GAAGATGGGT 5520
TATTGCATGT CACTTTTTTT TTTTTGTAAA ATAAAAACAT ACCTTAC 5567
Seq ID NO: C188 DNA Sequence Nucleic Acid Accession ff: NM_014324.1 Coding sequence: 89..1237
11 21 31 41 51
I . I I I I
GGCβCCGGGA TTGGGAGββC TTCTTGCAGβ CTGCTGGGCT GGGGCTAAGG GCTGCTCAGT 60 TTCCTTCAGC GGGGCACTGG GAAGCGCCAT GGCACTGCAG GGCATCTCGG TCGTGGAβCT 120 GTCCGGCCTG GCCCCβGGCC GTNTCTGTβC TATGGTCCTG GCTGACTTCG GGGCβCGTGT 180 GGTACGCGTG GACCGGCCCG GCTCCCGCTA CGACGTβAGC CGCTTGβGCC GGGGCAAGCG 240 CTCGCTAGTG CTGGACCTGA AGCAGCCβCβ GGAGCCGCGT βCTGCGGCGT CTGTGCAAGC 300 GGTCGGATGT GCTGCTGGAG CCCTTCCGCC GCGGTGTCAT GGAGAAACTC CAGCTGGGCC 360 CAGAGATTCT GCAGCGGGAA AATCCAAGGC TTATTTATGC CAGGCTGAGT GGATTTGβCC 420 AGTTCAGGAA AGCTTCTGCC GGTTAGCTGG CCACGATATC AACTATTTGG CTTTGTCAGG 480 TGTTCTCTCA AAAATTGGCA GAAGTGβTGA GAATCCGTAT GCCCCGCTGA ATCTCGTGGC 540 TGACTTTGCT GGTGGTGGCC TTATGTGTGC ACTGGβCATT ATAATGGCTC TTTTTGACCG 600 CACACGCACT GACAAGGGTC AGGTCATTGA TGCAAATATG GTGGAAGGAA CAGCATATTT 660 AAGTTCTTTT CTGTGGAAAA CTCAGAAATC GAGTCTGTGG GAAGCACCTC GAGGACAGAA 720 CATGTTGGAT GGTβGAGCAC CTTTCTATAC GACTTACAGG ACAGCAGATG GGGAATTCAT 780 GGCTGTTGGA GCAATAGAAC CCCAβTTCTA CGAGCTβCTG ATCAAAGGAC TTGGACTAAA 840 GTCTGATCAA CTTCCCAATC AGATGAGCAC GGATGATTGG CCAGAAATGA AGAAGAAGTT 900 TGCAβATGTA TTTGCAAAGA AGACβAAGGC AGAGTCGTGT CAAATCTTTG ACGGCACAGA 960 TGCCTGTGTG ACTCCGβTTC TGACTTTTGA GGAGGTTGTT CATCATGATC ACAACAAGGA 1020 ACGGGGCTCG TTTATCACCA GTGAGGAGCA GGACGTGAGC CCCCGCCTTG CACCTCTGCT 1080 GTTAAACACC CCAGCCATCC CTTCTTCCAA AGGGGATCCT TTCATAGGAG AACACACTGA 1140 GGAGATACTT GAAGAATTTG GATTCAGCCG AGAAGAGATT TATCAGCTTA ACTCAGATAA 1200 AATCATTGAA AGTAATAAGG TAAAAGCTAG TCTCTAACTT CCAGGCCCAC GβCTCAAGTG 1260 AATTT6AATA CTGCATTTAC AGTGTAGAGT AACACATAAC ATTGTATGCA TGGAAACATG 1320 GAGβAACAGT ATTACAGTGT CCTACCACTC TAATCAAGAA AAGAATTACA GACTCTGATT 1380 CTACAGTGAT GATTGAATTC TAAAAATGGT TATCATTAGG GCTTTTGATT TATAAAACTT 1440 TGGGTACTTA TACTAAATTA TGGTAGTTAT TCTGCCTTCC AGTTTGCTTG ATATATTTGT 1500 TGATATTAAβ ATTCTTGACT TATATTTTGA ATGGGTTCTA GTGAAAAAGG AATCATATAT 1560 TCTTCAAβAC ATCGATATAC ATTTATTTAC ACTCTT6ATT CTACAATGTA GAAAATGAGG 1620 AAATβCCACA AATTGTATGG TGATAAAAGT CACGTGAAAC AGAGTGATTG GTTGCATCCA 1680 GGCCTTTTGT CTTGGTGTTC ATGATCTCCC TCTAAGCACA TTCCAAACTT TACCAACAβT 1740 TATCACACTT TGTAATTTGC AAAGAAAAGT TTCACCTGTA TTGAATCAGA ATβCCTTCAA 1800 CTGAAAAAAA CATATCCAAA ATAATGAββA AATGTGTTGG CTCACTACGT AGAGTCCAGA 1860 GGGACAGTCA GTTTTAGGGT TGCCTGTATC CAGTAACTCG βββCCTGTTT CCCCGTGGGT 1920 CTCTGββCTG TCAGCTTTCC TTTCTCCATG TGTTTGATTT CTCCTCAGGC TGGTAGCAAG 1980 TTCTGGATCT TATACCCAAC ACACAGCAAC ATCCAβAAAT AAAGATCTCA GGACCCCCCA 2040 AAAAAAAAAA AAAAAAAAAA AAAAAAAA 2068
Seq ID NO: C189 DNA Sequence
Nucleic Acid Accession ft: XM_091332.1
Coding sequence: 1..1401
60
120
180
Figure imgf001318_0001
240
GCCTCCATCC ACAGCTGGGA GGAGAATGTC TTTGTATATG ACCTCGTGAA CAGCTGTGTT 300
CCCGGCATCC CAGCTGACGT CTGGACAGGC CTTCATGATC ACAGACAGGA AGGGCAGTTT 360
GAATGGACTG ATGGCTCATC CTATGACTAC AGCTACTGGG ATGGCAGCCA GCCAGATGAT 420
GGCGTCCACG CGGACCCAGA AGAAGAGGAC TGCGTGCAGA TATGGTACAG GCCTACCAGT 480
GAGCAGCTAC AGβCCCCAGA GCCCCAGTTA CCCTTATCAA TCTCAGAGGC CACAGATCTC 540
TATCTCCCTG AGGATTTCCC AGCTGAGCCC AAGCTCATGG ACCAGTCCTG GGTGTCCAGG 600
AAGAGCCTGA AACCATCCAA GAGTCATCTT ATGGAGCCAC CCACTCCAGT GβCCAAGCAC 660
CAAAAGGCAA AGACCCGACA TAGGAGCCTG CGCGGCGTCT GGTGGCCATC AGβTAAGGCT 720
GGGTCATGβA AAGAAAGAAT GAATGCAGAC TACGGGCGAA GAAAGCGATC GGCCCCGAGβ 780
CAGGAAGGCC GGCTCCGGTG CAGGGAGCGC CGCCTGCGGG CTGCTTCGGG CCAGGGTCGA 840 CCCGAGGGCC AGCGCAAGCA GCGGCAACAG GAGCGCCAGG AGAGAGGCTG GGAAGAACTG 900 GGAGβGGTGT CCCCAATGCG GGGCGCCCAA GCGTGGCAGC ACGGGCTGGG AGCGGGGAGC 960 CAGCGGGGTG CGGCGCCGGA GTβCβGGGAG AACCACCAGG CGCCβGAATT GGGGAGCACG 1020 TGGAGGGGGC AGCGGCTCCA GCCCCAGACC GCCGCGCTCT GTCACTTTGC ATTAAGAAAG 1080 CTTCCGGGGA ATGCACACGG CCTGGCCGCC GCCTTCGTGC AGCCCGCCCT GCAGGTGCAG 1140 GAAGAAAAGA ATAATCGCAC CCGTTTCTCA GGTGCTTACT TCACCATGTC CGATCCCACG 1200 TGTCACCAAG ATAGCAAGGA GCAGTCTTTA AGGCGACACG GCAβAGAGGC AGAAAAAGAT 1260 GGβCCTTACC GβTTAGTTAA GAAAAAAAGA GGACCTGTTG CCTGTCCCTC TAGCTTTGAA 1320 CTACAAAGTG GAGGGβAAGT TTGTCTGGAT TTTCCTGTAG AACTGAGGGC AGGGACCTGG 1380 ATTGCTCGAG AACCTCCATA A 1401
Seq ID NO: C190 DNA Sequence
Nucleic Acid Accession ft: XM_054869.2
Coding sequence: 26..2902
1 11 21 31 41 51
I I I I I I
TAGACβCβGA GCCCAAGGAG GTAAAATGCA CACTTGCTGC CCCCCAGTAA CTTTGGAACA 60 GGACCTTCAC AGAAAAATGC ATAGCTGGAT GCTGCAGACT CTAGCGTTTG CTGTAACATC 120 TCTCGTCCTT TCGTβTGCAG AAACCATCGA TTATTATGGG GAAATCTGTG ACAATGCATG 180 TCCTTGTGAG GAAAAGGACG GCATTTTAAC TGTGAGCTGT GAAAACCGGG GGATCATCAG 240 TCTCTCTβAA ATTAGCCCTC CCCGTTTCCC AATCTACCAC CTCTTGTTGT CCGGAAACCT 300 TTTGAACCβT CTCTATCCCA ATGAGTTTGT CAATTACACT GGGGCTTCAA TTTTGCATCT 360 AG6TAGCAAT GTTATCCAGβ ACATTGAGAC CGGGGCTTTC CATGGGCTAC GGGGTTTGAG 420 GAGATTGCAT CTAAACAATA ATAAACTGGA ACTTCTGCGA GATGATACCT TCCTTGGCTT 480 GGAGAACCTG GAGTACCTAC AGGTCβATTA CAACTACATC AβCGTCATTG AACCCAATGC 540 TTTTGGGAAA CTGCATTTGT TGCAββTGCT TATCCTCAAT GACAATCTTT TGTCCAGTTT 600 ACCCAACAAT CTTTTCCCTT TTGTGCCCTT AACGCACTTG GACCTCCGGG GGAACCGGCT 660 GAAACTTCTG CCCTACGTGG GGCTCTTGCA GCACATGGAT AAAGTTGTGG AGCTACAGCT 720 GGAβGAAAAC CCTTGGAATT GTTCTTGTGA GCTGATCTCT CTAAAGGATT GGTTGGACAG 780 CATCTCCTAT TCAGCCCTGG TGGGGGATGT AGTTTGTGAG ACCCCCTTCC GCTTACACGG 840 AAGGGACTTG GACGAGGTAT CCAAGCAGGA ACTTTGCCCA AGGAGACTTA TTTCTGACTA 900 CGAGAT6AGG CCGCAGACGC CTTTGAGCAC CACGGGβTAT TTACACACCA CCCCGGCGTC 960 AGTCAATTCT GTGGCCACTT CTTCCTCTβC TGTTTACAAA CCCCCTTTGA AGCCCCCTAA 1020 GββGACTCGC CAACCCAACA AGCCCAGGGT GCGCCCCACC TCTCGGCAGC CCTCTAAGGA 1080 CTTGGGCTAC AGCAACTATG GCCCCAGCAT CGCCTATCAG ACCAAATCCC CGβTGCCTTT 1140 GGAGTGTCCC ACCGCGTGCT CTTGCAACCT GCAGATCTCT GATCTGGGCC TCAACGTAAA 1200 CTGCCAGGAG CGAAAGATCG AGAβCATCGC TCAACTGCAG CCCAAGCCCT ACAATCCCAA 1260 GAAAATGTAT CTGACAGAGA ACTACATCGC TGTCGTGCGC AGGACAGACT TCCTGGAGGC 1320 CACGGGGCTG GACCTCCTGC ACCTGGGGAA TAACCGCATC TCGATGATCC AGβACCGCGC 1380 TTTCGGGGAT CTCACCAACC TGAGGCGCCT CTACCTGAAT GGCAACAGGA TCGAGAGGCT 1440 GAGCCCGGAG TTATTCTATG GCCTGCAGAG CCTGCAGTAT CTCTTCCTCC AGTACAATCT 1500 CATCCGCGAG ATTCAGTCTG GAACTTTTGA CCCGGTCCCA AACCTCCAGC TGCTATTCTT 1560 GAATAACAAC CTCCTGCAGG CCATGCCCTC AGGCGTCTTC TCTGGCTTGA CCCTCCTCAG 1620 βCTAAACCTG AGGAGTAACC ACTTCACCTC CTTGCCAGTG AGTCGAGTTT TGGACCAGCT 1680 GAAGTCACTC ATCCAAATCG ACCTGCATGA CAATCCTTGG GATTGTACCT GTβACATTGT 1740 GGGCATGAAG CTGTββGTGG AGCAGCTCAA AβTCGGCGTC CTAGTGGACG AGGTGATCTG 1800 TAAGGCGCCC AAAAAATTCG CTGAGACCGA CATGCGCTCC ATTAAGTCGG AGCTGCTGTG 1860 CCCTGACTAT TCAGATGTAG TAGTTTCCAC GCCCACACCC TCCTCTATCC AGGTCCCTGC 1920 GAGGACCAGC GCCGTGACTC CTGCGGTCCG GTTGAATAGC ACCGGGGCCC CCGCGAGCTT 1980 GGGCGCAGGC GGAGGGGCGT CGTCGGTGCC CTTGTCTGTG TTAATTCTCA GCCTCCTCCT 2040 GGTTTTCATC ATGTCCGTCT TCGTGβCCGC CGGGCTCTTC GTGCTβGTCA TGAAGCGCAG 2100 GAAGAAGAAC CAGAGCβACC ACACCAβCAC CAACAACTCC GACGTGAGCT CCTTTAACAT 2160 GCAGTACAGC GTGTACGGCG GCGGCGGCGG CACGGGCGGC CACCCACACG CGCACGTGCA 2220 TCACCGCGGG CCCGCGCTGC CCAAGGTGAA GACGCCCGCG GGCCACGTGT ATGAATACAT 2280 CCCCCACCCA CTGGGCCACA TGTGCAAAAA CCCCATCTAC CGCTCCCGAG AGGGCAAGTC 2340 CGTAGAGGAT TACAAAGACC TGCACGAGCT CAAGGTCACC TACAGCAGCA ACCACCACCT 2400 GCAGCAGCAG CAGCAGCCGC CGCCβCCACC GCAGCAGCCA CAGCAGCAGC CCCCGCCGCA 2460 GCTGCAGCTG CAGCCCGGGG AGGAGGAGAG GCGGGAAAGC CACCACTTGC GGAGCCCCGC 2520 CTACAGCGTC AGCACCATCβ AGCCCCGGGA GGACCTGCTG TCGCCGGTGC AGGACGCCGA 2580 CCGCTTTTAC AGGGGCATTT TAGAACCAGA CAAACACTGC TCCACGACCC CCGCCGGCAA 2640 TAGCCTCCCG GAATATCCCA AATTCCCGTG CAGCCCCGCT GCTTACACTT TCTCCCCCAA 2700 CTATβACCTG AGACGCCCCC ATCAGTATTT GCACCCGGGβ GCAGGGGACA GCAGGCTACG 2760 GGAACCGGTG CTCTACAGCC CCCCGAGTGC TGTCTTTGTA GAACCCAACC GGAACGAATA 2820 TCTGGAGTTA AAAGCAAAAC TAAACGTTGA GCCGGACTAC CTCGAAGTGC TGGAAAAACA 2880 GACCACGTTT AGCCAGTTCT AAAAGCAAAG AAACTCTCTT GGAGCTTTTG CATTTAAAAC 2940 AAACAAGCAA GCAGACACAC ACAGTGAACA CATTTGATTA ATTGTGTTGT TTCAACGTTT 3000 AGGGTGAAGT GCCTTGGCAC GGGATTTCTC AGCTTCGGTG GAAGATACGA AAAGGGTGTG 3060 CAATTTCCTT TAAAATTTAC ACGTGGGAAA CATTTGTGTA AACTGGGCAC ATCACTTTCT 3120 CTTCTTGCGT GTGGGGCAGG TGTGGAGAAG GGCTTTAAGG AGGCCAATTT GCTGCGCGββ 3180 TβACCTGTGA AAGGTCACAG TCATTTTTGT AGTGGTTGβA AGTGCTAAGA ATβGTGGATG 3240 ATCGCAGAGC ATAGATTCTA CTCTTCCTCT TTTGCTTCCT CCCCCTCCCC CGCCCCTGCC 3300 CCACCTCTCT TTCTCCCCTT TTAAGCCATG GGTGGGTCTA ACTGGCTTTT GTGGAGAAAT 3360 TAGCACACCC CAACTTTAAT AGGAAATTTG TTCTCTTTTT CCGCCCCTCT CCTTCTCTCC 3420 TCCCCTCCCC TCCCTTCTCA TTCCTTTTCT TTGTTTTTAA AGGATGTGTT TGTATGCATT 3480 CTβGACATTT GAATTAAAAA AAAAGTATTG TGATCCTGTA AAGGATCACC ATAGATGTGG 3540 ACAAATCATT AAAATTACAG AGCTATATGA TCCATAATTG ATTAGTCAAA ATAACTTATT 3600 GATGAAATAT ACAAATATTT TATTGTAGCA CCTATTTTTA TATGCACATT TAGCATTCCT 3660 CTTTCCTTCA CTATTTAGCC TATGATTTTG CAGAGGTCTC ACACTGTATT AGGATCTGCA 3720 TTTCTAAAAC TGACGTGGTA TCAGGAAGGC ATTTTCAATC ATTCAAAATG TGGAGAATTT 3780 AATGGCTAAA TCTTTAAAAG CCAATGCAAC CCACCCAATT GAATCTGCAT TTTCTTTTAA 3840 GAAAACAGAG CTGATTGTAT CCCAATGTAT TTTAAAAAAT AGGGCAATTG ATTGGGCCAT 3900 TCCGAGAGAA TTGTTTGCAA GTTTTGGGTT TTATTAGAAA ATATTTGAAA GTATTTTTAT 3960 TAATGAACCA AAATβACATG TTCATTTGAC TACTATTGTA GCCGATTTTC GATTGTTTAA 4020 CCAAACCCAG TTGCATTTGT ACAGATCCAC GTGTACTGGC ACCTCAβAAG ACCAAATCAT 4080
GGACTGTACA AGTCTCTATA CAATGTCTTT ATCCCTGTGG GCAGCAAGCA ATGATGATAA 4140
TGACAAACAG GATATCTGTA AGATGGGGCT ACTGTTGTTA CAGTCTCATA TGTATCCCAG 4200
CACATGTAAT TTTTTAAATA GTTTCTGAAT AAACACTTGA TAACTATGTC 4250
Seq ID NO: C191 DNA Sequence
Nucleic Acid Accession ff: NM_000793.2
Coding sequence: 401..1222
11 21 31 41 51
GCCTGCAGAG AGAGGCACTT TGCACCACAG ACAGATAGCA AGAAGGGAAA GACAGAGAGT 60
GAGAAAAAAG AGGAGTCAGT CGCTCCTGGG GAAGGGAGAG AGTGAGACTG GGAGAAAGAG 120
AAGCACAGAA AGTGTGTGTA AAACGGAGTA AAGAAAGAAA AAAAAAAAAC TACCCTTAAA 180
GCACATTTAA AAAAAAAAAA CTCTGGCAAT TCAAGAAAGA AACAGGCTAC GTTTAAAGAG 240
CATAGAGACA ATGAAAGGCT AAAGAAAATT TTAAAATCTC TGCCACAGTC TCATAGGTGC 300
TTGGAAATGA AAGTAGAACT GCCTGTCTTT AACGGACTCT GACAGAGAGG GTGAAGGGGA 360
ACCAGAGCGC ACAAGGGAAC TGACTCAGGA GGCAGAGAAG ATCGGCATCC TCAβCGTAGA 420
CTTGCTGATC ACACTGCAAA TTCTGCCAGT TTTTTTCTCC AACTGCCTCT TCCTGβCTCT 480
CTATGACTCG GTCATTCTGC TCAAGCACGT GGTGCTGCTG TTGAGCCGCT CCAAGTCCAC 540
TCGCββAβAG TGGCGGCGCA TGCTGACCTC AGAGGGACTG CGCTGCβTCT GGAAβAβCTT 600
CCTCCTCGAT GCCTACAAAC AGGTGAAATT GGGTGAGGAT GCCCCCAATT CCAGTGTGGT 660
GCATGTCTCC AGTACAGAAG GA6GTGACAA CAGTGGCAAT GGTACCCAGG AGAAGATAGC 720
TGAGGGAGCC ACATGCCACC TTCTTGACTT TGCCAGCCCT GAGCGCCCAC TAGTGGTCAA 780
CTTTGGCTCA GCCACTTGAC CTCCTTTCAC GAGCCAGCTG CCAGCCTTCC GCAAACTGβT 840 ββAAβAβTTC TCCTCAGTGG CTGACTTCCT GCTGGTCTAC ATTGATGAGG CTCATCCATC 900
AGATGGCTGG GCGATACCGG GGGACTCCTC TTTGTCTTTT GAGGTGAAGA AGCACCAGAA 960
CCAGGAAGAT CGATGTGCAG CAGCCCAGCA GCTTCTGGAG CGTTTCTCCT TβCCβCCCCA 1020
GTGCCGAGTT GTGGCTGACC GCATGGACAA TAACGCCAAC ATAGCTTACG GGGTAGCCTT 1080
TGAACGTGTG TGCATTGTGC AGAGACAGAA AATTGCTTAT CTGGGAGGAA AGGGCCCCTT 1140
CTCCTACAAC CTTCAAGAAG TCCGGCATTG GCTGGAGAAβ AATTTCAGCA AGAGATGAAA 1200
GAAAACTAGA TTAGCTGGTT AAAGGTATGA TTATAAGAGA GCTTATTGTT TTAAAAAGTT 1260
ATATAAAGGC AAGGAAATTA AGAACTGAAT CCATATTTCA ACAGAGCCCT ATTGGCTTAC 1320
TGAAAGACAG GAβTTTATCT ATCGGAAGAA CATGAATCTC TAACAGCTCC ATACTTCTTT 1380
CACTACTCAA ATGGCATTGG GCTGAGTAAG TAACCATATC ACCTCTCTTC TTAGTAAAAA 1440
GCCCTATGTβ AAAAβATCCC AAGATGGAGA GGAAGAAACG CTAATTCAGC ATGTGTTCAT 1500
TCTβCATTβA GAAGGAACTG ATACATCTGA TGCATGCTTT GAGACCAGAA GAAAAGACTT 1560
ACCTGAATAA TTACTACATT AGGβAAGCTA CTGTCTACGT TAAGATAAAG GGTATTGCCT 1620
TGβCTCTATT TGGCATGGAT GGAGCCCAGT TGGAAAATTC CCAAATATTA CAACAAGTCC 1680
TTGAACCCAG GCCATGTGGT TAGACGTTGβ TGTTAAGGTT AGACCTTATG TTAGAGTCAT 1740
TTCTGATβTT CCAGCTTCTA GCCATGTAGT GCTCTCAGTC TTCATACCCC AGAAATTATT 1800
GGTATATTTG TAGATACCGA GAATGATCCC TCAGTCTGAG AGGTTAGAAT GATCATCTGT 1860
AATCTGAGGG TTAATTTCTA GGCAGGTGGA GAGAGTGβTA AAAAAGAAAT GAAATTGACA 1920
AGCTAGGAAA GAGGAGGCAG AAAGATTTCG AAAATTCACA GAGTTTCACC CTTAAβCTGT 1980
AGAGAGTCGG TCACATTTGT TAGCCACGGA AACATAGAAA CATACACAAG GCCAGAAAAA 2040
GAAGAAGGAG CTCAACTAAA AGTGGCATAG AGAATACACA TATAAAAACA ATATATTTCT 2100
CATATβCTCC TAGAGAGGAG AAAGGGGTGA TTGAAAGAAA AAAAAATACT TAAATATTTG 2160
TAATTGTGAG GGGTTTCTTT TGGAAATAAT TACTTTTGAA CCATGTATGT GGTATGTATA 2220
TTTTCAGTGG GTTAATTATA CCCCATCATA CCTATTAAAG GAAAACCAGT GGGTCTGGTG 2280
GTGCTGGTCT TTTCCTCCCC ATTCCTACAA TTTCTATGTG GCCCAAGTCA TTCCTAATCT 2340
TGGTCTCTAT AGCAGTGTTC TCTCTGAATG CTGAGCTGAA GAAATTATAC GTACATACAC 2400
ACATACATAC ATACATACAA ATATATGTAT ATATATTCTC AGCTGCTGCG GGAGGTAGGT 2460
ACCATGGCCA TTCAGCACAG CCTTGATTTC CTCCCAAAGT AGGTGAGCTA TAGTGAAGAA 2520
TAGGTGCAAA CAAACAAGCT TACTTCCATT GCAAAATAGA AGAAGAGGAA GTTAGAGATA 2580
ATTCTGATCA ATCATTTTGG AGGCTTTGTT ATAAGGCAAC CCCCGGTATA TCATGGAATT 2640
TCCATTGACA TTTGAATTTG GACTTGGATC TTCCCTTGGT CCCATTAGCT GAGGTTTAGT 2700
AATCTAAAGT CCCTATAGTA TATGATTATA ATGCTATTTT AAAAAATATA TATATAAAAT 2760
ATTTTTTTCT TTTTAAAATA GACACTATAG TTTTACCCAT AAGTAATATT TAAAGATTAT 2820
AGCTCCCAAA AGAATGGACC AACCACTTTC GTATCATAAT TTCTTTTTGG TAAATATGAG 2880
ACTATTATGA AATCATAGTA TATGATTGTA TTTAAAGGTA CAATCAAAGG ATCTTTTGTC 2940
CATTCCATTA ATAACTGAAT AAAAAATAAA TAAAATGGAT AGAAAAAAAC TAAAGTTGAA 3000
AATACATTCT TAAACTAGTT GTCTGAAATG AGAAAAGAGT GAGAACTAGG TGTGCAAGAA 3060
CCAAACGTAT TTTATTTTAT TTTTTAAATG GGAGCAACAT ATCAGTCGTG TCACCAGCTG 3120
GTATATTGTG TAAATATTAA AGCTCCATTG G ACTGATTT TTCATGGCAA CATCAGCTTT 3180
CTAATGTTCT AAATTCTATA AAAACCACCC ACAAAGAAAC AAAGCAAATT TCATTATCTA 3240
ATGAGTTGCT GGAAAATCAT ATTGAGAATA ATTATTTCAG ATTCCTCAGT TGTTAACTTC 3300
TACATTCAAG GGCTTATCTC TGCCCCCATT GATTTTTAAC CTCAAAATGG TGTGAGATTT 3360
ACTGTGGAAC CCTAAAGCAG TAAAATAAAA AACCTGGTTG CAGCACATTC ACACTGTTGT 3420
CCTTAAAATT CCCCTTTTTT CTCTATGTAC GATAAAGTAA CAGTATGTCA GATAAGCCGG 3480
TGGGGGGATG AGATTAGGCT GAGGCAGTGC TAGTCAACTG GGGGAAAAGG ATGATGGAAA 3540
AATCACCCAG TTGTGCTATA TTTTTAAAGA AGGAGGTCGT TTATGTGTGC AGACAATTCT 3600
CCCTGAGGTT AGCCCAATGG AGAAATGAAG CAGAGGAAGG AAACATAGAA AGACATGGGC 3660
TATCAGGGAG GAAGATβTTC AATAGAACAT GCAAGAATTT CTGGAAGAAA GGCT6TCGAA 3720
GGGCCAATGG AGAAAATGAA TGβACAAAGC TCAβGAATCC CTACGCTATG TAGAATGTTC 3780
TTGGTGTTAT CAGGGTTAAG CCCTGTAATT ATGTAACCTA TTTATCGCAA CATGAATTTT 3840
TATGATTTCT TGTGATGTAT TCTTTTATGA AATTAACAAG AACTCATTAT TTTGAGGTAG 3900
AGGAAAATCA ATGCTTTATC TGATATGCTG AGAAATTATT AGATTGCCAA TACTCATGTG 3960
CGTTTCATCT GTTTTATAAG GTTTGTTCCT TTGAAGAATT βTAβTTCTTA GTCCCACAGG 4020
GAAATGTGTA TCTATTTATA TATCATAGTA TAAATCTATG ATATATTTAT ATCATATATA 4080
AAAGTCTGAG TTCTCTTTCT TAGTCCCTAA TCATGTTTCT CCCATAGGCT GTGTTTACAT 4140 βGAGCTATCβ GTTTAGCCTT TTAAGCTTCA TTAGCTTGTC TATTATTGAA ATAGTTTCCA 4200
AGAAATTTTA GATATTATCA TAACATCTGG GTCTACTCAA ACACTTATTG TTTGAAAGAC 4260
TTATGTCTTG GACCTATCAA AAACTGACTT TATTTATTGC TTAGTβAAAA TACTAGTGGG 4320
ATCAACAATG ATTTTCTTGA ATGGGCATGA ATGGAGATGC CCβCACAβTA ATGTAGAAAT 4380 GTTTCATACA GCTATTAAAA TGTAACTGAC CTCCTTAGAG GCAGATTAGT AACTGTTCCT 4440
ACTTTGTATA GCTAAGTGAC AGTCACTTAA CTTACATGAC TTTCTTTTTT CACATTGGGT 4500
CTCTGβTCCT GTGTCTTCAC CTCATTTATA GCACGTCTCC TTGATTTTTG GTAGTATCAA 4560
CTTCCCAGTG ATCTGTTCAG TTAAGTTCTT CTCCCGTTAA CCAGGAAGTG CTTATTCTCT 4620
CATCACAGTβ GGAAGAATAG CCTATTGTCT TTCATTTTGC CTGAGTGTAT TTTACTATTT 4680
GGGCTCTGAA ATAAAAATTA TGAAATATGG TGAGGTCACA TGTTGGTGCT GCCTTGCTGC 4740
ATAAAATTCT AGGAGGGCAG GTTAGGAGAC AGTTATGTAT GGCCTTTCGG GAAAATTCAA 4800
AGGGTGGGAT TACAAGGGTG TTCCTCAGGC ATGCCCCTAT GGGCCCTATG TGGAAGCAAG 4860
AAGAATTGAC TGATTTACAG GACTTCTCTT TATGTCAATC TTAAGAGGAT GGATGAATCT 4920
GGACATTTGT TCCACCCGAC CTCTGACTGA TGGTTTGGAA AATAACTTTA ATTAGGATCA 4980
TATGAGCATT GAAAAAGGAA AAATGTAGAC TCTGACTTCC GTCCCACTGA AGGATTAATG 5040
AAAACCTTTA CTAGCATTTA GAβCTTTTCA GAACATCCCC ACTGTCATGT GTCTCAGCAG 5100
TGGAGACTGC AAGTAAGGCT TTTAATTTTA GGAGGTTTTT TTTTTTTTTT TTTTTTCCCC 5160
TAAATGGTAT GGCCAAAAGT CAGAGTTAAA ATATATATAG TTAGATTCCA ACTTCCTCCT 5220
TCACTCTAAA AATAGAATCC AAACCCACTC TTCATATATG CTTCCAGAAT GGGGCTTAAG 5280
TACCAATCTC TGCTTTGCAA TGGGCACAAT CTTGCTCATG TCCTGAGGCT CTCTAAGAAA 5340
AGAGAGGATC TAGGATGGGA GAGCTAGAAA GTTGCTAACT GGGAAGAACA AGGCCCTGAG 5400
GGGTTGβTCT ACCAATCTGG GAAGATTTCA AAACAAACTT CTCGCAACTG AAGGAAGGCT 5460
GAAGGCTGCT GCAAGTCATT GAβTGACTTT AGGATGAGCA AAACATTGGG CCACTTCCTA 5520
ATGCCCTATG TGTATAGTAC CAGAAGCAAC GTCTCAGACT TAACAGACCC AGCTCTGTTC 5580
CAAGGTGAGT CTGAACCAAT AGAAAGCAAA CATGTGCAGA TATCCAAACA AGACTGCTCA 5640
TGCAAGTCGG GGCTGGCTAC CCGTCTTAGG CAGCAACAGC AGAGCTCCAG GGAGCTTATT 5700
CAATATTTAC TGAGACTTCG AAGACCCAGC AGATGTTTAA TGAAGTCACT ATTTTGGCTC 5760
AAACCCTCCA CTTCTCCCCC TCCCCTCAAA AAGCCAACAG GTAAACACAT AAATGAAAGA 5820
AACCCACAGA AGGGGATGGG AAATAAAGAA AATTCTCTCA AβACTTCTCC AGGCCCATGT 5880
CACTGGTCAG CGTGGTTTTT ATGTGTATTA GGATTGGGGG ATGT6AAGAA ATAAGTATCC 5940
AGTACTTTAT AACCAAAGCA ATTAAATGAT ATTGGGGTAG GGAATGTTβG CCAGTTTTGT 6000
TTAGTTTTGC CATCACATTG TCACCCAGAC CTCACCTAGC CCCAAGTAAT CGGGCGCCCC 6060
GAAGAGGGAG ACAGAGATGT GCCAβAGTTG ACCCAGTGTG CGGATGATAA CTACTGACGA 6120
AAGAGTCATC GACCTCAGTT AGTββTTCGA TGTAGTCACA TTAGTTTGCC TCTCCCCATC 6180
TTTGTCTCCC TGGCAAGGAG AATATGCβGG ACATGATGCT AAGAGCCCTG GGTAAATGTG 6240
GTGAGAATGC ACGCGTGCAT ATGCTACACA TATGTGCTTC TCAGTTGCAG AAAATGAACT 6300
GCTTTGGGAG ATTATCAGTA GAAAGAGTGT TATCATATTG GTGCTGAGTG CTATGTGTGC 6360
TTATACAATT TGTTCTTGTA TTTTAATAAA CTTTGAATAA AAGAATAAAA AAAAAAAAAA 6420
AAAAAAAAA 6429
Seq ID NO: C192 DNA Sequence
Nucleic Acid Accession ff: NM_006549.2
Coding sequence: 824..2590
60
Figure imgf001321_0001
120 AAAAAAAAAT GGGAGTGGGC CGGGCGCGGT GACTCACACC TGTAATCCCA GCACTTTCGG 180 AGβCCAAGGC GGGTGGATCA CGAGGTCAGG AATTCAAGAT TAGCCTGGAC AACATGGTGA 240 AACCCCATCT CTACGAAAAA TACAAAAATT AGCCAAGTAT GGTGGCCGGC GCCTGTAATC 300 CCAGCTACTC GGβAGACTGA GβCAβAGAAC TGCTTGAACC TGGGAGGCAG AGGTTGCAGT 360 GATCCGAGAT CGCGTCACTG CACTCCAG∞ TGGGCGACAG AGCGAGACTC CGTTTCAGAA 420 AAGAAAAAAA AAAAAAAAAA AAAAAGGβAβ TCGGGGTGGA GCTCTCATTG GCTCGTTGCA 480 TGTGAGTGTC CCTACGβCCT AGAAATACCA GAGAAGCACA TCGGAACGGG CTGGAAATCC 540 ACCCAGTTAA CTAGAGGGCT TTGAACCTTT TATTAACTTG GAGGTTGACT CTCCTGTCAA 600 CTCGATTCCC TTTTGGCTGT TTGGCAGGGT CAGTGAGACA TCCCCTGGGT CGCTCGACCC 660 CGTAGGACGG TTCAGGGAGC CCTCCAGGTC TTCGTTTCTC CTCTTCCCCG CACAGTGCTG '720 TTATCCAGCT GGGGGATCCA ACGCACACTT AAGGCTCCAG CAAAGTGGCT CCGCTGCCGG 780 ATGGGAGTβC CCCAGTGTGC TGGATGAAGC TCGCGCATGC ACCATGTCAT CATGTGTCTC 840 TAGCCAGCCC AGCAGCAACC GGGCCGCCCC CCAGGATGAG CTGGGGGGCA GGGGCAGCAG 900 CAGCAGCGAA AGCCAGAAGC CCTβTβAGGC CCTGCGGGGC CTCTCATCCT TGAGCATCCA 960 CCTGGGCATG GAGTCCTTCA TTGTGGTCAC CGAGTGTGAG CCGGGCTβTG CTGTGGACCT 1020 CGGCTTGGCG CGGGACCGGC CCCTGGAGGC CGATββCCAA GAGGTCCCCC TTGACTCCTC 1080 CGGGTCCCAG GCCCGGCCCC ACCTCTCCGG TCGCAAGCTG TCTCTGCAAG AGCGGTCCCA 1140 GGGTGGβCTG GCAGCCGGTG GCAβCCTGGA CATGAACGGA CGCTGCATCT GCCCGTCCCT 1200 GCCCTACTCA CCCGTCAGCT CCCCGCAGTC CTCGCCTCGG CTGCCCCGGC GGCCGACAGT 1260 GGAGTCTCAC CACGTCTCCA TCACGGGTAT GCAGGACTGT GTGCAGCTGA ATCAGTATAC 1320 CCTGAAGGAT GAAATTGGAA AGGGCTCCTA TGGTGTCGTC AAGTTGGCCT ACAATGAAAA 1380 TGACAATACC TACTATβCAA TGAAGGTGCT GTCCAAAAAG AAGCTGATCC GGCAGGCCGG 1440 CTTTCCACβT CβCCCTCCAC CCCGAGGCAC CCGGCCAGCT CCTGGAGGCT GCATCCAGCC 1500 CAGGGGCCCC ATTGAGCAGG TGTACCAGGA AATTGCCATC CTCAAGAAGC TGβACCACCC 1560 CAATGTGGTG AAGCTGβTGG AGGTCCTGGA TGACCCCAAT GAGGACCATC TGTACATGGT 1620 GTTCGAACTG GTCAACCAAG GGCCCGTGAT GGAAGTGCCC ACCCTCAAAC CACTCTCTGA 1680 AGACCAββCC CGTTTCTACT TCCAGGATCT GATCAAAGGC ATCGAGTACT TACACTACCA 1740 GAAGATCATC CACCGTGACA TCAAACCTTC CAACCTCCTG GTCGGAGAAG ATGGGCACAT 1800 CAAGATCGCT GACTTTGGTG TGAGCAATGA ATTCAAGGGC AGTGACGCGC TCCTCTCCAA 1860 CACCGTGGGC ACGCCC6CCT TCATGGCACC CGAGTCGCTC TCTGAGACCC GCAACATCTT 1920 CTCTGGβAAG GCCTTGGATG TTTGGGCCAT GGβTGTGACA CTATACTGCT TTGTCTTTGG 1980 CCAGTGCCCA TTCATGGACG AGCGGATCAT GTGTTTACAC AGTAAGATCA AGA6TCACGC 2040 CCTGGAATTT CCAGACCAGC CCGACATAGC TGAGGACTTG AAGGACCTGA TCACCCGTAT 2100 GCTGGACAAG AACCCCGAGT CGAGGATCGT GGTGCCGGAA ATCAAGCTGC ACCCCTGGGT 2160 CACGAGGCAT GGGGCGGAGC CGTTGCCGTC GGAGGATGAG AACTGCACGC TGGTCGAAGT 2220 GACTCAAβAG GAGGTCGAGA ACTCAGTCAA ACACATTCCC AGCTTGGCAA CCGTGATCCT 2280 GGTGAAGACC ATβATACGTA . AACGCTCCTT TGGGAACCCA TTCGAGGGCA GCCGGCGGGA 2340 GGAACGCTCA CTGTCAGCGC ! CTGGAAACTT GCTCACCAAA AAACCAACCA GGGAATGTGA 2400 GTCCCTGTCT GAGCTCAAGG ! AAGCAAGGCA GCGAAGACAA CCTCCAGGGC ACCGACCCGC 2460 CCCCCGTGGG GGAGGAGGAA . GTGCTCTTGT GAGAGβCAGT CCCTGCGTGG AAAGTTGCTG 2520 GGCCCCCGCC CCCGGCTCCC CCGCACGCAT GCATCCACTG CGGCCGGAGG AGGCCATGGA 2580 GCCCGAGTAG CTGCCTGGAT CGCTCGACCT GGCATGCGCG CCGCβTCGCC TCTGGGGGGC 2640 TGCTGCACCG CGTTTCCATA GCAGCATGTC CTACGGAAAC CCAGCACGTG TGTAGAGCCT 2700 CGATCGTCAT CTCTGGTTAT TTGTTTTTTC CTTTGTTGTT TTAAAGGGGA CAAAAAAAAA 2760 AAAAAAAGGA CTTGACTCCA TGACGTCGAC CGTGGCCGCT GGCTGGCTGG ACAGGCGβGT 2820 GTGAG6AGTT GCAGACCCAA ACCCACGTCC ATTTTGGGAA ATTGCTTTTT AAAAGATTTT 2880 TATGCCAAAA ATCCTTCATT GTGATTTTCA GAACCACGTC AGATATACCA AGTGACTGTG 2940 TβTGGGGTTT GACAACTGTG GAAAGGCGAG CAGAAAACTC CGGGGGTCTG AGGCCATGGA 3000 GGTGGTTGCT GCATTTGAGA GGGAGTAGGG GGCTAGATGT GGCTCCTAGT GCAAACCGGA 3060 0 AACCATGGCA CCTTCCAGAG CCGTGGTCTC AAGGAGTCAG AGCAGGGCTG GCCCTCAGTA 3120 GCTGCAGGGA GCTTTGATGC AACTTATTTG TAAGAAGGAT TTTTAAATTT TTTATGGGTA 3180 GAATTGTAGT CAGGAAAACA GAAAGGGCTT GAAATTTAAT AAGTGCTGCT GGAAGGββAT 3240 TTTCCAAGCC TGGAAGGGTA TTCAGCAGCT GTGGTCGGGA AACATTTCTC CTGAAAGACT 3300 GAACGTGTTT CTTCATGACA GCTGCTCAAA GCAGβTTTCT GAGATAGCTG ACCGAGCTCT 3360 5 GGTAAATCTC TTTCTCAAAT TACGAAAACT TCAGGGTGAA ATCCTATGCT TTCATGTACA 3420 TTACATGGCT TAAGATTAAA CAAAAACATT TTTCAAGTCT CTAACTAGAβ TGAACTCTAG 3480 AGCACA6TAG TTCAGAAACT ATTTAGAGCT TCCAGGATAT ATTTCACAGC TTCAGGCATG 3540 TGATCAGTTA GAGCCGATGA AACCTATGCC CGCCTGTATA TATATTAGCA GCTTAGCTAG 3600 TTCATAACCT GTATATTCTA AAGACTGCTA AGGTTTTGTT TTCATTTTAA ATCCTAβCTG 3660 0 ATTGTTβTββ TCAATGAAAT ACCCAGTTTC TGAAGGGCCA GβTGGGAAAT GCTTTCACTβ 3720 GACCAACACA CAAATGATCA TCCTGAGGAT CTGAβCTTCC CTAGACTCCA CACAATAACC 3780 TTGGGGCACC CTTTTAGAGA AGACTGTTGA AACCCACAGC ACTCGTTGGG GTATGAGβAA 3840 ACCAGGGCTT GGCACAGGAA GTTCCCCTTT GTAGCTAAAA GTCCAGAAAG AAAGGβTTCA 3900 TCTTTTTGAC TTCCAACTGA TATTGββAAG TTTGGTTGAG GTTCAAGTGT GACTCCTTCC 3960 5 AGAGCCACAG GTAGGGGAGT GTGAAGTTGA GGGββAGGAA AGCTGGAAGG ACTCTGCCTT 4020 GGGAGATTCC CAGCTCTGCT TTCCAGCGCT TGβTGGAATC TGβGCTGGGG AAAGACGβCA 4080 CCGGGAAACT CTGCTTCCCC ATTGTTTCCA TCTGATCAGC TGTGGTGTGA GGACTTCTCA 4140 GACAAAGGCA AGGCCTCGTG CCCCTGCCCA GCCCATTCAT GGAGCCCTGG GCCTTCTTGG 4200 CTTCCATAGA TCCTAAGCTC TTGACTGTAG TTTAGCCAGA CTTGTTTTGC TATCTTATAA 4260 0 GCAGTTCAGA ATTAGGGAAT GCTGGTTTTG AAGAGCAAAG GACAGGTAGT CTAGAGAGGG 4320 TCGTCTGGCC TGCTTGCTGG GTCTTTGTAA CCCAGCACTT CCTCTTGCCC TCCTGGCTTT 4380 ATGTTTATGG GAGAGGACTC AATAGCTCCA CCCCTTCTGG CACCAGATGG GGCTTGβTTA 4440 GTTTGCAATA AGCACCTTGC AGAGGTTAAA GCCAGCGGGT CCCTAGTCTT AGGCCCAGCC 4500 TGCTTGTGTG GGCTCTGGCC TGGCCTβGTG GCTGβCCCAG GβGGCAGCAG TGCTTAGAGC 4560 5 TTCTGCAGGG CTTCTCTTGT TTACACAGCT GCATCAGACA ATGCCATTTC TCCCCACCAC 4620 GGAACCTTCC ATCTAAGATT TCTTCCAGGG AATGCCAGCA ATCAGGCAGC ACCCAGCTGT 4680 GGGGβCAGTG GGGTGGGGGA GACCCACATT GATGACTTTT TTTTTTTCTT TTAATGAAGA 4740 AACACCAAAG AAAGCTGTGG AAAGGACCTG CCCCACATGA AAAGGATAAG CCAAGATGGC 4800 TGTAAACACA GAGCATTTGA GCTGCCACTC TTGGAGCACA TTGATTTTTC AAAAGCCAGC 4860 0 TCTGTCAGGA AAGGAGGTGC TGTTATGACA GCTCTTCCAG TGGGCAAAGA GGACGCCCAT 4920 AATTTCTTCC ATTGCTAGCT CATCTGTGGG ACCAATTTβG TGTAAGCAAC CTGTGGCCTG 4980 CACTTGTGGC CTCGAAG6AA GCACAAACCC TCCATCCACT TCCCATTTCC TCTGCCCTTT S040 TCCACCTCCC CCTTCCATCC CACCAGCTGC CAGTGGCTCC CAGAAAGCCT TATTGAGCCC 5100 CTTGTTGACA CTTGGGCCTG CGGAGGCCTT TCCCTACTGG TCTGGCCTTT CCTGAGAGGC 5160
45 AGGTCTTCCβ TCCTCAGAGC CTTTCTGGAA CAAβGAGAAT GCCTGTGCAG GTGGACACAC 5220 AGGCCTGGCC TGTCGCTCTC ACTTGTCTTC CAGCGGGGAG CTTCACGTTG CCGAGTGGAA 5280 βAACCATGAC CTCCACTTGC TTCCAAGGTG CTAGGGAAGT TTCAGGGTAC GCTGGTTCCC 5340 CTCTCCAGCT GGAGGCCGAG TTTCTGGGGA CTGCAGATTT TTCTACTCTG TGATCGATTC S400 AATGCCCGAT GCTTCTGTTT CATTCCCGAC CCTTTCTACT ATGCATTTTC CTTTTATCAG 5460
50 GTGTATAAAG TTAAATACTG TGTATTTATC 1 ACTAAAAAGT ACATGAACTT AAGAGACAAC 5520 TAAGCCTTTC GTβTTTTTCC ACAGGTGTTT AAGCTTCTCT GTACAGTTGA AATAAACAGA 5580 CAGCAAAATG GTAAAAAAAA AAAAAAAAAA . A 5611
Seq ID NO : C193 DNA Sequence D D Nucleic Acid Accession ft : NM_018646
Coding sequence : 217 . .2394
11 21 31 41 51
60 I I I I I
GCTCTGCCAA GTGTAACAAA CTCACAGCCC TCTCCAAACT GGCTGGGGCT GCTGGGAGAC 60 TCCCAAGGAA CTCGTCAGGA AGGCAGGAGA CAGβAGACGG GACCTCTACA GGGAGACGGT 120 GGGCCGGCCC TTGGGGGGGC TGATGTGGCC CCAAGGCTGA GTCCCGTCAG GGTCTCGCCT 180 CGGCCTCAGG CCCCCAAGGA GCCGGCCCTA CACCCCATGG GTTTGTCACT GCCCAAGGAG 240 AAAGGβCTAA TTCTCTGCCT ATGGAGCAAG TTCTGCAGAT GGTTCCAGAG ACβGGAGTCC 300
65 TGGGCCCAGA GCCGAGATGA GCAGAACCTG CTGCAβCAGA AGAGGATCTG GGAGTCTCCT 360 CTCCTTCTAG CTGCCAAAGA TAATGATGTC CAGGCCCTGA ACAAGTTGCT CAAGTATGAG 420 GATTGCAAGβ TGCACCAGAG AGGAGCCATG GGββAAACAG CGCTACACAT AβCAGCCCTC 480 TATGACAACC TGGAGGCCGC CATGGTGCTG ATGGAGGCTG CCCCGGAGCT GGTCTTTGAG 540 CCCATGACAT CTGAGCTCTA TGAβGGTCAG ACTGCACTCC ACATCGCTGT TGTGAACCAβ 600
70 AACATGAACC TGGTGCGAGC CCTGCTTGCC CGCAGGGCCA GTGTCTCTGC CAGAGCCACA 660 GGCACTGCCT TCCGCCβTAG TCCCTGCAAC CTCATCTACT TTCGGGAβCA CCCTTTGTCC 720 TTTGCTGCCT GTGTGAACAG TGAGGAGATC GTGCGGCTGC TCATTGAGCA TGGAGCTGAC 780 ATCCGGGCCC AGGACTCCCT GGGAAACACA GTGTTACACA TCCTCATCCT CCAGCCCAAC 840 AAAACCTTTG CCTGCCAGAT GTACAACCTG TTGCTGTCCT ACGACAGACA TGGGGACCAC 900
75 CTGCAGCCCC TGGACCTCGT GCCCAATCAC CAGGGTCTCA CCCCTTTCAA GCTGβCTGGA 960 GTGGAGGGTA ACACTGTGAT GTTTCAGCAC CTGATGCAGA AGCGGAAGCA CACCCAGTGG 1020 ACGTATGGAC CACTGACCTC GACTCTCTAT GACCTCACAG AGATCGACTC CTCAGGGGAT 1080 GAGCAGTCCC TGCTGGAACT TATCATCACC ACCAAGAAGC GGGAGGCTCG CCAGATCCTG 1140 GACCAGACGC CGGTGAAGGA GCTGGTGAGC CTCAAGTGGA AGCGGTACGG GCGGCCGTAC 1200
80 TTCTGCATGC TGGGTGCCAT ATATCTGCTG TACATCATCT GCTTCACCAT GTGCTGCATC 1260 TACCGCCCCC TCAAGCCCAG GACCAATAAC CGCACGAGCC CCCGGGACAA CACCCTCTTA 1320 CAGCAGAAGC TACTTCAGGA AGCCTACATG ACCCCTAAGβ ACGATATCCG βCTGGTCGGG 1380 βAGCTGGTGA CTGTCATTGG GGCTATCATC ATCCTGCTGG TAGAGGTTCC AGACATCTTC 1440 AGAATGGGGG TCACTCGCTT CTTTGGACAG ACCATCCTTG GGGGCCCATT CCATGTCCTC 1500 ATCATCACCT ATGCCTTCAT GGTGCTGGTG ACCATGGTGA TGCGGCTCAT CAGTGCCAGC 1560
GGGGAGGTGG TACCCATGTC CTTTGCACTC GTGCTGGGCT GGTGCAACGT CATGTACTTC 1620
GCCCGAGGAT TCCAGATGCT AGGCCCCTTC ACCATCATGA TTCAGAAGAT GATTTTTGβC 1680
GACCTGATGC GATTCTGCTG GCTGATGGCT GTββTCATCC TGGGCTTTGC TTCAGCCTTC 1740
TATATCATCT TCCAGACAGA GGACCCCGAG GAGCTAGGCC ACTTCTACGA CTACCCCATG 1800
GCCCTGTTCA GCACCTTCGA GCTGTTCCTT ACCATCATCG ATGGCCCAGC CAACTACAAC 1860
GTGGACCTGC CCTTCATGTA CAGCATCACC TATGCTGCCT TTGCCATCAT CGCCACACTG 1920
CTCATGCTCA ACCTCCTCAT TGCCATGATG GβCGACACTC ACTGGCGAGT GGCCCATβAβ 1980
CGGGATGAGG TGTβGAGGβC CCAGATTGTG GCCACCACGG TGATGCTGGA GCGGAAGCTC 2040
CCTCGCTGCC TGTGGCCTCG CTCCGGGATC TGCGβACβGG AGTATGGCCT GGGAGACCGC 2100
TGGTTCCTGC GβGTGGAAβA CAGGCAAGAT CTCAACCGβC AGCGGATCCA ACGCTACGCA 2160
CAGGCCTTCC ACACCCGGββ CTCTGAGGAT TTGGACAAAG ACTCAGTGGA AAAACTAGAG 2220
CTGGGCTGTC CCTTCACCCC CCACCTGTCC CTTCCTATGC CCTCAGTGTC TCGAAGTACC 2280
TCCCGCAGCA βTGCCAATTG GGAAAGGCTT CGGCAAGGGA CCCTGAGGAG AGACCTGCGT 2340
GGGATAATCA ACAGGGGTCT GGAGGACGGG GAGAGCTGGG AATATCAGAT CTGACTGCGT 2400
GTTCTCACTT CGCTTCCTGG AACTTGCTCT CATTTTCCTG GGTGCATCAA ACAAAACAAA 2460
AACCAAACAC CCAGAGGTCT CATCTCCCAG GCCCCAGGGG AGAAAGAGGA GTAGCATGAA 2520
CGCCAAβGAA TGTACGTTGA GAATCACTGC TCCAGGCCTG CATTACTCCT TCAGCTCTGG 2580
GGCAGAGGAA GCCCAGCCCA AGCACGGGGC TGβCAGGGCG TGAGGAACTC TCCTGTGβCC 2640
TGCTCATCAC CCTTCCGACA GGAGCACTGC ATGTCAGAGC ACTTTAAAAA CAGGCCAGCC 2700
TGCTTGGGCG CTCGGTCTCC ACCCCAGβGT CATAAGTGGG GAGAGAGCCC TTCCCAGGGC 2760
ACCCAGGCAG GTGCAGGGAA GTGCAGAGCT TGTGGAAAGC GTGTGAGTβA GGGAGACAββ 2820
AACGGCTCTG GGGGTGGGAA GTGGGGCTAG GTCTTGCCAA CTCCATCTTC AATAAAGTCG 2880
TTTTCGGATC CCTGAAAAAA AAAAAAAAAA AAAAAAAA 2918
Seq ID NO: C194 DNA Sequence
Nucleic Acid Accession ft: NM.021910.1
Coding sequence: 260..601
11 21 31
GTTCTCCACA ACTGCCAGCA ATCCTTCCAC CAGGCAAAAC ACATCATCTA AGGAAAAGAA 60
GTGAGGTTTG CTTAGGGCβT GGCAGCTTCG GATAAACGCA GGACTCCGCC TGGCAGCCCG 120
ATTTCTCCCG GAACCTCTGC TGAGCCTGGT GAACCACACA GGCCCGAGTT TCACCCAGTC 180
CCCACTCCAC GGTGCAGCTG CGGCTTATCT CTCAGCCCAG CGAGATGCCA GCCTTCCTGT 240
CCCGGGCCAG CGCTCTGACA TGCAGAAGGT GACCCTGGGC CTGCTTGTGT TCCTGGCAGG 300
CTTTCCTGTC CTGGACGCCA ATGACCTAGA AGATAAAAAC AGTCCTTTCT ACTATGACTG 360
GCACAGCCTC CAGGTTGGCG GGCTCATCTG CGCTGGGGTT CTGTGCGCCA TGGGCATCAT 420
CATCGTCATG AβTGAGTGβA GGAGCTCGGG GGAGCAGGCG GGCCGGGGCT GGGGCTCCCC 480
TCCCCTGACC ACTCAβCTCT CCCCAACAGG TGCAAAATGC AAATGCAAGT TTGGCCAGAA 540
GTCCGGTCAC CATCCAGGGG AGACTCCACC TCTCATCACC CCCGGCTCAG CCCAAAGCTG 600
ATGAGGACAG ACCAGCTGAA ATTGGGTCGA GGACCGTTCT CTGTCCCCAG GTCCTGTCTC 660
TGCACAGAAA CTTGAACTCC AGGATGGAAT TCTTCCTCCT CTGCTGGGAC TCCTTTGCAT 720
GβCAGGGCCT CATCTCACCT CTCGCAAGAG GGTCTCTTTG TTCAATTTTT TTTAATCTAA 780
AATGATTGTG CCTCTGCCCA AGCAGCCTGG AGACTTCCTA TGTGTGCATT GGGGTβGGβC 840
TTGGGGCACC ATGAGAAGβT TGGCGTGCCC TGGAGGCTGA CACAGAGGCT GGCACTGAGC 900
CTGCTTGTTG GGAAAAGCCC ACAGGCCTGT TCCCTTGTGG CTTGGGACAT GGCACAGGCC 960
CGCCCTCTGC CTCCTCAGCC ATGGGACCTC ATATGCAATT TGGGATTTAC TAGTAGCCAA 1020
AAGGAATGAA AGAGAGCTCT AACCAGATGG AACACTGGAA CATTCCAGTβ GACCCTGGAC 1080
CATTCCAGGA AAACTGGGAC ATAGGATCGT CCCGCTATGA TGGAAGTGTT CAGACAGTTT 1140
ATAATAGTAA GCCCCTGTGA CCCTCTCACT TACCCCGAGA CCTCACTTTA TTACAAGATC 1200
TTTCCAAATA CCCAAATATC CCTGCAAGCC CGTTAAATAA TTCCCTATGC TACCCTTAAT 1260
AACATACAAT GACCACATAG TGTGAGAACT TCCAACAAGC CTCAAAGTCC CTTGAβACTC 1320
CCCAATACCT AATAAGGCAT GCGAAATGTT CTCATGAACT ACCCCACAAC ACGCCTAAAA 1380
CTCAAAACAC CCAAAAATAT CTCCTCCAAT GTCCTGAGAC ATGAACCCAA AAAGAGACCC 1440
ACAATAAACT CGTGACTTGT CCCCTC 1466
Seq ID NO: C195 DNA Sequence
Nucleic Acid Accession #: NM_005971.2
Coding sequence: 176..439
60
120
Figure imgf001323_0001
180
GAAGGTGACC CTGGGCCTGC TTGTGTTCCT GβCAGGCTTT CCTGTCCTGG ACCCCAATGA 240
CCTAGAAGAT AAAAACAGTC CTTTCTACTA TGACTGGCAC AGCCTCCAGG TTGGCGGβCT 300
CATCTGCGCT GGGGTTCTGT GCGCCATGGG CATCATCATC GTCATGAGTG CAAAATGCAA 360
ATGCAAGTTT GGCCAGAAGT CCGGTCACCA TCCAGGGGAG ACTCCACCTC TCATCACCCC 420
AGGCTCAGCC CAAAGCTGAT GAGGACAGAC CAGCTGAAAT TGGGTGGAGG ACCGTTCTCT 480
GTCCCCAGGT CCTGTCTCTG CACAGAAACT TGAACTCCAG GATGGAATTC TTCCTCCTCT 540
GCTGGGACTC CTTTGCATGG CAGGβCCTCA TCTCACCTCT CGCAAGAGGG TCTCTTTGTT 600
CAATTTTTTT TAATCTAAAA TGATTGTGCC TCTGCCCAAG CAGCCTGβAG ACTTCCTATG 660
TGTGCATTGG GGTGGGGCTT GGGGCACCAT GAGAAG6TTG GCGTGCCCTG GAGGCTGACA 720
CAGAGGCTGG CACTGAGCCT GCTTGTTGGG AAAAGCCCAC AGGCCTGTTC CCTTGTGGCT 780
TGGGACATGG CACA6GCCCG CCCTCTGCCT CCTCAGCCAT GGGACCTCAT ATGCAATTTG 840
GGATTTACTA βTAGCCAAAA GGAATGAAAG AGAGCTCTAA CCAGATGGAA CACTGβAACA 900
TTCCAGTGGA CCCTGGACCA TTCCAGGAAA ACTGGGACAT AGGATCGTCC CGCTATGATG 960
GAAGTGTTCA GACACTTTAT AATAGTAAGC CCCTGTGACC CTCTCACTTA CCCCGAGACC 1020
TCACTTTATT ACAAGATCTT TCCAAATACC CAAATATCCC TGCAAGCCCG TTAAATAATT 1080
CCCTATGCTA CCCTTAATAA CATACAATGA CCACATAβTG TGAGAACTTC CAACAAGCCT 1140
CAAAGTCCCT TGAGACTCCC CAATACCTAA TAAGGCATGC GAAATGTTCT CATGAACTAC 1200
CCCACAACAC GCCTAAAACT CAAAACACCC AAAAATATCT CCTCCAATGT CCTGAGACAT 1260 GAACCCAAAA AGAGACCCAG AATAAACTCG TGACTTGTCC CCTC
Seq ID NO: C196 DNA Sequence
Nucleic Acid Accession ft: NM_004961.2
Coding sequence: 55..1575
1 11 21 31 41 51
I I I I I I
GCCAGAGCGT GAGCCGCGAC CTCCGCβCAC GTG6TCGCGC CGGTCTCCGC GGAAATGTTG 60
TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAGTCGAG GGTCGAGGβA 120
CCTCAGACTG AATCAAAGAA TGAAGCCTCT TCCCGTGATG TTGTCTATGG CCCCCAGCCC 180
CAGCCTCTGG AAAATCAGCT CCTCTCTGAG GAAACAAAGT CAACTGAGAC TGAGACTGGG 240
AGCAGAGTTG βCAAACTβCC AGAAGCCTCT CGCATCCTGA ACACTATCCT GAGTAATTAT 300
GACCACAAAC TGCGCCCTGG CATTGGAGAG AAGCCCACTG TGGTCACTGT TGAGATCGCC 360
GTCAACAGCC TTGGTCCTCT CTCTATCCTA GACATGGAAT ACACCATTGA CATCATCTTC 420
TCCCAGACCT βGTACGACGA ACGCCTCTGT TACAACGACA CCTTTGAGTC TCTTGTTCTG 480
AATGGCAATG TGGTGAGCCA GCTATGGATC CCββACACCT TTTTTAGGAA TTCTAAGAGG 540
ACCCACGAGC ATGAGATCAC CATGCCCAAC CAGATGGTCC GCATCTACAA GGATGGCAAG 600
GTGTTGTACA CAATTAGGAT GACCATTGAT GCCGGATGCT CACTCCACAT GCTCAGATTT 660
CCAATGGATT CTCACTCTTG CCCTCTATCT TTCTCTAGCT TTTCCTATCC TGAGAATGAG 720
ATGATCTACA AGTGGGAAAA TTTCAAGCTT GAAATCAATG AGAAGAACTC CTGGAAGCTC 780
TTCCAGTTTG ATTTTACAGG AGTGAGCAAC AAAACTGAAA TAATCACAAC CCCAGTTββT 840
GACTTCATGG TCATGACGAT TTTCTTCAAT GTGAGCAGGC GGTTTGGCTA TGTTGCCTTT 900
CAAAACTATG TCCCTTCTTC CGTCACCACG ATGCTCTCCT GGGTTTCCTT TTGGATCAAG 960
ACAGAGTCTG CTCCAβCCCG GACCTCTCTA GGβATCACCT CTGTTCTGAC CATGACCACG 1020
TTGββCACCT TTTCTCβTAA GAATTTCCCG CGTGTCTCCT ATATCACAGC CTTGGATTTC 1080
TATATCGCCA TCTGCTTCGT CTTCTGCTTC TGCGCTCTGT TGGAβTTTGC TGTGCTCAAC 1140
TTCCTGATCT ACAACCAGAC AAAAGCCCAT GCTTCTCCTA AACTCCGCCA TCCTCGTATC 1200
AATAGCCGTG CCCATGCCCG TACCCGTGCA CGTTCCCGAG CCTGTGCCCG CCAACATCAG 1260
GAAGCTTTTG TCTGCCAGAT TGTCACCACT GAGGGAAGTβ ATGGAGAGGA GCGCCCGTCT 1320
TGCTCAGCCC AGCAβCCCCC TAGCCCAGGT AGCCCTGAGG GTCCCCGCAG CCTCTGCTCC 1380
AAGCTGGCCT GCTGTGAGTG GTGCAAGCGT TTTAAGAAGT ACTTCTGCAT GGTCCCCGAT 1440
TGTGAGGGCA GTACCTGGCA GCAβββCCGC CTCTGCATCC ATGTCTACCG CCTGGATAAC 1500
TACTCGAGAG TTGTTTTCCC AGTGACTTTC TTCTTCTTCA ATGTGCTCTA CTGGCTTGTT 1560
TGCCTTAACT T6TAGGTACC AGCTGGTACC CTGTGGGGCA ACCTCTCCAG TTCCCCAGGA 1620
GGTCCAAGCC CCTTGCCAAG GGAGTTGGGβ GAAAGCAGCA GCAGCA6CAG GAGCGACTAG 1680
AGTTTTTCCT GCCCCATTCC CCAAACAGAA GCTTGCAGAG GGTTTGTCTT TGCTGCCCCT 1740
CTCCCCTACC TGGCCCATTC ACTGAGTCTT CTCAGCAGAC CATTTCAAAT TATTAATAAA 1800
TGGGCCACCT CCCTCTTCTT CAAGGAGCAT CCGTGATGCT CAGTGTTCAA AACCACAGCC 1860
ACTTAGTGAT CAGCTCCCTA AAACCATGCC TAAGTACAGG CGGATTAGCT ATCTTCCAAC 1920
AATGCTGACC ACCAGACAAT TACTGCATTT TTCCAGAAGC CCACTATTGC CTTTGTACTG 1980
CTTTCGGCCC AGTTCTGGCC TCAGCCTCAA AGTGCACCGA CTAGTTGCTT GCCTATACCT 2040
GGCACCTCAT TAAGATGCTG GGCAGCAβTA TAACAGGAGG AAGAGATCCC TCTCCTTTGG 2100
TCAGATTATT ATGTTCTCAG TTCTCTCTCC CTGCTACCCC TTTCTCTGCA GATAGATAGA 2160
CACTGGCATT ATCCCTTTAG GAAGAGGGGG GGGCAGCAAβ AGAGCCTATT TGGGACAGCA 2220
TTCCTCTCTC TCTGCTβCTG TGACATCTCC CTCTCCTTβC TGGCTCCATC TTTCGTCTGC 2280
ACTACCAATT CAATGCCCTT CATCCAATGG GTATCTATTT TTGTGTGTGA TTATAGTAAC 2340
TACTCCCTGC TTTATATGCC ACCCTCTTCC TTCTCTTTGA CCCCTGTGAC TCTTTCTGTA 2400
ACTTTCCCAG TGACTTCCCC TAGCCCTGAC CCAGGCACTA GGCCTTGGTG ACTTCCTGGG 2460
GCCAAGAAAC TAAGGAAACT CGGCTTTβCA ACAGGCATTA CTCGCCATTG ATTGGTGCCC 2520
ACCCAGGGCA CACTGTCGGA GTTCTATCAC TTGCTTGACC CCTGGACCCA TAAACCAGTC 2580
CACTGTTATA CCCGGGGCAC TCTAACCATC ACAATCAATC AATCAAATTC CCTTAAATTT 2640
GTATGβCACT GGAACTTTGG CAAAGCACTT TTGACAAGTT GTGTCTGATT GGAGCTTCAT 2700
GATAGCCTTG TGACATCTTT AGGGCAGβAT TCTTATCCCC ATTTTGCAGA TGAAAACCCT 2760
GAGTCACAGA TTTCTGTGGG ACTGTGGATC TCACTGGAAG CTATCCAAGA GCCCACTGTC 2820
ACCTTCTAGA CCACATGATA GGGCTAGACA GCTCAGTTCA CCATGATTCT CTTCTGTCAC 2880
CTCTGCTGGC ACACCAGTGG CAAGβCCCAβ AATGGCGACC TCTCTTTAGC TCAATTTCTG 2940
GGCCTGAGGT GCTCAGACTG CCCCCAAGAT CAAATCTCTC CTGGCTGTAG TAACCCAGTG 3000
GAATGAATTT GGACATGCCC CAATGCTTCT ATATGCTAAC TβAAATCTGT GTCTGTAATT 3060
TGTTGGGGGG TGGATAGGGT GGGGTCTCCA TCTACTTTTT GTCACCATCA TCTGAAATGG 3120
GGAAATATGT AAATAAATAT ATCAGCAAAG CAAAAAGAAA AAAAAAAA 3168
Seq ID NO: C197 DNA Sequence
Nucleic Acid Accession ft: NM_021984.1
Coding sequence: 572..1753
1 11 21 31 41 51 1 1 1 1 | 1 | 1 | 1 | 1
GCCAGAGCGT GAGCCGCβAC CTCCGCGCAG GTGGTCGCGC CGGTCTCCGC GGAAATGTTG 60
TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAGTCGAG AACATGTATA 120
CAGAGAAGTG CTCAAATCAT AAGTGTACAG CTGATGAGTT GTCAAAAAAT GACCACAGCG 180
GTGTAAAGAA AGCCAAATCA AGGACCCGAA TGTGAGCAGG ACCTCAGAAG CCCCCTTTβT 240
CACTGCCTCC CAGCAAAGGC AGCACTATCC GGACTTCTAA CACCATCGGβ TCβAGGβACC 300
TCAGACTGAA TCAAAGAATG AAβCCTCTTC CCGTGATGTT GTCTATGGCC CCCAβCCCCA 360
CCCTCTGGAA AATCAGCTCC TCTCTβAGGA AACAAAGTCA ACTGAGACTG AGACTGGGAG 420
CAGAβTTGGC AAACTGCCAG AAGCCTCTCβ CATCCTGAAC ACTATCCTβA GTAATTATGA 480
CCACAAACTG CGCCCTGGCA TTGGAGAGAA GCCCACTCTG CTCACTCTTG AGATCTCCGT 540
CAACAGCCTT GGTCCTCTCT CTATCCTAGA CATGGAATAC ACCATTGACA TCATCTTCTC 600
CCAGACCTGG TACGACGAAC βCCTCTCTTA CAACGACACC TTTGAGTCTC TTGTTCTGAA 660
TGGCAATGTG GTGAGCCAGC TATGGATCCC GGACACCTTT TTTAGGAATT CTAAGAββAC 720
CCACGAGCAT GAGATCACCA TGCCCAACCA GATGGTCCGC ATCTACAAGβ ATGGCAAGGT 780
GTTGTACACA ATTAGGATGA CCATTGATGC CGGATGCTCA CTCCACATGC TCAGATTTCC 840
AATGGATTCT CACTCTTGCC CTCTATCTTT CTCTAGCTTT TCCTATCCTG AGAATGAGAT 900
GATCTACAAG TGGGAAAATT TCAAGCTTGA AATCAATGAG AAGAACTCCT GGAAGCTCTT 960 CCAGTTGGAT TTTACAGGAG TGAGCAACAA AACTGAAATA ATCACAACCC CAGTTGGTGA 1020
CTTCAT6GTC ATGACβATTT TCTTCAATGT GAGCACGCGG TTTGGCTATG TTGCCTTTCA 1080
AAACTATCTC CCTTCTTCCβ TGACCACGAT GCTCTCCTGG GTTTCCTTTT GGATCAAGAC 1140
AGAGTCTGCT CCAGCCCGGA CCTCTCTAGG GATCACCTCT GTTCTGACCA TGACCACGTT 1200
GGGCACCTTT TCTCGTAAGA ATTTCCCGCG TGTCTCCTAT ATCACAGCCT TGGATTTCTA 1260
TATCβCCATC TGCTTCGTCT TCTGCTTCTG CGCTCTGTTG βAGTTTGCTG TGCTCAACTT 1320
CCTGATCTAC AACCAGACAA AAGCCCATGC TTCTCCTAAA CTCCGCCATC CTCGTATCAA 1380
TAGCCGTGCC CATGCCCGTA CCCGTGCACG TTCCCGAGCC TGTGCCCGCC AACATCAGGA 1440
AGCTTTTGTG TGCCAGATTG TCACCACTGA GGGAAGTGAT GGAGAGGAGC GCCCGTCTTG 1500
CTCAGCCCAG CAGCCCCCTA GCCCAGGTAG CCCTGAGGGT CCCCGCAGCC TCTGCTCCAA 1560
GCTGGCCTGC TGTGAGTGGT GCAAGCGTTT TAAGAAGTAC TTCTGCATGG TCCCCGATTG 1620
TGAGGGCAGT ACCTGGCAGC AGGCCCGCCT CTGCATCCAT GTCTACCGCC TβGATAACTA 1680
CTCGAGAGTT GTTTTCCCAG TGACTTTCTT CTTCTTCAAT GTGCTCTACT GβCTTGTTTG 1740
CCTTAACTTG TAGGTACCAG CTGGTACCCT GTGGGGCAAC CTCTCCAGTT CCCCAGGAGG 1800
TCCAAGCCCC TTGCCAAGGG AGTTGGGGGA AAGCAGCAGC AGCAGCAGGA βCGACTAGAG 1860
TTTTTCCTGC CCCATTCCCC AAACAGAAGC TTGCAGAβGG TTTGTCTTTG CTGCCCCTCT 1920
CCCCTACCTG GCCCATTCAC TGAGTTTTCT CAGCAGACCA TTTCAAATTA TTAATAAATβ 1980
GGCCACCTCC CTCTTCTTCA AGGAGCATCC GTGATGCTCA GTGTTCAAAA CCACAGCCAC 2040
TTAGTGATCA GCTCCCTAAA ACCATβCCTA AGTACAGβCG GATTAGCTAT CTTCCAACAA 2100
TGCTβACCAC CAGACAATTA CTGCATTTTT CCAGAAGCCC ACTATTGCCT TTCCAGTGCT 2160
TTCGGCCCAG TTCTGGCCTC AGCCTCAAAG TGCACCGACT AGTTGCTTGC CTATACCTGG 2220
CACCTCATTA AGATGCTGGG CAGCAGTATA ACAGGAGβAA GAGATCCCTC TCCTTTGGTC 2280
AGATTATTAT GTTCTCAGTT CTCTCTCCCT GCTACCCCTT TCTCTGCAGA TAGATAGACA 2340
CTGGCATTAT CCCTTTAGGA AGAGGGGGGG GCAGCAAGAG AGCCTATTTG GGACAGCATT 2400
CCTCTCTCTC TGCTGCTGTG ACATCTCCCT CTCCTTGCTG GCTCCATCTT TCGTCTGCAC 2460
TACCAATTCA ATGCCCTTCA TCCAATGGGT ATCTATTTTT GTGTβTGATT ATACTAACTA 2520
CTCCCTGCTT TATATGCCAC CCTCTTCCTT CTCTTTGACC CCTGTGACTC TTTCTGTAAC 2580
TTTCCCAGTG ACTTCCCCTA GCCCTGACCC AGGCACTAGG CCTTGGTGAC TTCCTGGGGC 2640
CAAGAAACTA AGGAAACTCG GCTTTGCAAC AGGCATTACT CGCCATTGAT TGGTGCCCAC 2700
CCAGGGCACA CTGTCGGAGT TCTATCACTT GCTTGACCCC TGGACCCATA AACCAGTCCA 2760
CTGTTATACC CGGGGCACTC TAACCATCAC AATCAATCAA TCAAATTCCC TTAAATTTGT 2820
ATGGCACTGG AACTTTGGCA AAGCACTTTT GACAAβTTGT GTCTGATTGG AGCTTCATGA 2880
TAGCCTTβTG ACATCTTTAG CGCAGβATTC TTATCCCCAT TTTGCAGATG AAAACCCTGA 2940
GTCACAGATT TCTGTGGGAC TGTG6ATCTC ACTGGAAβCT ATCCAAβAβC CCACTGTCAC 3000
CTTCTAGACC ACATGATAGG GCTAGACAGC TCAβTTCACC ATGATTCTCT TCTGTCACCT 3060
CTGCTGGCAC ACCAGTCGCA AGGCCCAGAA TGGCGACCTC TCTTTAGCTC AATTTCTGGG 3120
CCTGAGGTGC TCAGACTGCC CCCAAGATCA AATCTCTCCT GGCTGTAβTA ACCCAGTGGA 3180
ATGAATTTGG ACATGCCCCA ATGCTTCTAT ATGCTAAGTG AAATCTGTGT CTGTAATTTG 3240
TTGGGGGGTG GATAGGGTGG GGTCTCCATC TACTTTTTGT CACCATCATC TGAAATGGGG 3300
AAATATGTAA ATAAATATAT CAGCAAAGC 3329
Seq ID NO: C198 DNA Sequence
Nucleic Acid Accession #: NM_021987.1
Coding sequence: 572..1657
11 21 31 41
GCCAGAGCGT GAGCCGCGAC CTCCGCGCAG GTGGTCGCGC CGGTCTCCGC GGAAATGTTG 60
TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAGTCGAG AACATGTATA 120
CAGAGAAGTG CTCAAATCAT AAGTGTACAG CTGATGAβTT GTCAAAAAAT βACCACAGCG 180
GTGTAAAGAA ACCCAAATCA AGGACCCGAA TGTGAβCAGG ACCTCAGAAβ CCCCCTTTGT 240
CACTGCCTCC CAβCAAAβGC AGCACTATCC βGACTTCTAA CACCATCGGG TCGAGGGACC 300
TCAβACTβAA TCAAAGAATG AAGCCTCTTC CCGTGATGTT GTCTATGβCC CCCAGCCCCA 360
GCCTCTGGAA AATCAGCTCC TCTCTGAGGA AACAAAGTCA ACTGAβACTG AGACTGGGAG 420
CAGAGTTGGC AAACTGCCAG AAGCCTCTCG CATCCTGAAC ACTATCCTGA GTAATTATGA 480
CCACAAACTG CGCCCTGGCA TTGGAGAGAA GCCCACTGTG CTCACTCTTG AβATCTCCβT 540
CAACAGCCTT GGTCCTCTCT CTATCCTAGA CATGGAATAC ACCATTGACA TCATCTTCTC 600
CCAGACCTGG AATTCTAAGA GGACCCACGA GCATGAGATC ACCATGCCCA ACCAGATGGT 660
CCGCATCTAC AAGGATGGCA AGGTGTTGTA CACAATTAGG ATGACCATTG ATGCCGGATG 720
CTCACTCCAC ATGCTCAGAT TTCCAATGGA TTCTCACTCT TGCCCTCTAT CTTTCTCTAG 780
CTTTTCCTAT CCTGAGAATG AGATGATCTA CAAGTGGGAA AATTTCAAβC TTGAAATCAA 840
TGAGAAβAAC TCCTGGAAGC TCTTCCAGTT TGATTTTACA GGAGTGAGCA ACAAAACTGA 900
AATAATCACA AGCCCAGTTG GTGACTTCAT GGTCATGACG ATTTTCTTCA ATGTGAGCAβ 960
GCGGTTTGGC TATGTTGCCT TTCAAAACTA TGTCCCTTCT TCCGTGACCA CβATGCTCTC 1020
CTGGGTTTCC TTTTGGATCA AGACAGAGTC TGCTCCAGCC CGGACCTCTC TA6GGATCAC 1080
CTCTGTTCTG ACCATGAGCA CGTTGGGCAC CTTTTCTCGT AAGAATTTCC CGCGTGTCTC 1140
CTATATCACA GCCTTGGATT TCTATATCGC CATCTGCTTC GTCTTCTGCT TCTGCβCTCT 1200
GTTGGAGTTT GCTGTGCTCA ACTTCCTGAT CTACAACCAG ACAAAAGCCC ATβCTTCTCC 1260
TAAACTCCGC CATCCTCGTA TCAATAGCCG TGCCCATGCC CGTACCCGTG CACβTTCCCG 1320
AGCCTGTGCC CGCCAACATC AGGAAGCTTT TGTGTGCCAG ATTGTCACCA CTGAGGGAAG 1380
TGATGGAGAG GAGCβCCCGT CTTGCTCAGC CCAGCAGCCC CCTAGCCCAG GTAGCCCTGA 1440
GGGTCCCCGC AGCCTCTGCT CCAAGCTGGC CTGCTGTβAG TGGTGCAAβC GTTTTAAGAA 1500
GTACTTCTGC ATGGTCCCCG ATTGTGAGGG CAGTACCTGG CAGCAGGGCC GCCTCTGCAT 1560
CCATGTCTAC CGCCTGGATA ACTACTCGAG AGTTGTTTTC CCAGTGACTT TCTTCTTCTT 1620
CAATGTGCTC TACTGGCTTG TTTGCCTTAA CTTGTAββTA CCAGCTGGTA CCCTGTGGGG 1680
CAACCTCTCC AGTTCCCCAG GAGGTCCAAG CCCCTTGCCA AGGGAGTTβG GGGAAAGCAG 1740
CAβCAGCAGC AGGAGCGACT AGAGTTTTTC CTGCCCCATT CCCCAAACAG AAGCTTGCAG 1800
AGGGTTTGTC TTTGCTGCCC CTCTCCCCTA CCTGGCCCAT TCACTGAGTT TTCTCAGCAβ 1860
ACCATTTCAA ATTATTAATA AATGGGCCAC CTCCCTCTTC TTCAAGGAGC ATCCGTGATG 1920
CTCAGTGTTC AAAACCACAG CCACTTAGTG ATCAGCTCCC TAAAACCATG CCTAAGTACA 1980
GGCGGATTAG CTATCTTCCA ACAATGCTGA CCACCACACA ATTACTGCAT TTTTCCAGAA 2040
GCCCACTATT GCCTTTGCAG TGCTTTCGGC CCAGTTCTGG CCTCAGCCTC AAAGTGCACC 2100
GACTAGTTGC TTGCCTATAC CTGGCACCTC ATTAAGATGC TGGGCAGCAG TATAACAGGA 2160
GGAAGAGATC CCTCTCCTTT GGTCAGATTA TTATGTTCTC AGTTCTCTCT CCCTGCTACC 2220 CCTTTCTCTG CAGATAGATA GACACTGGCA TTATCCCTTT AGGAAGAGGG GGGGGCAGCA 2280
AGAGAGCCTA TTTGGGACAG CATTCCTCTC TCTCTGCTGC TGTGACATCT CCCTCTCCTT 2340 βCTββCTCCA TCTTTCGTCT GCACTACCAA TTCAATGCCC TTCATCCAAT GGβTATCTAT 2400
TTTTβTGTGT GATTATAGTA ACTACTCCCT GCTTTATATG CCACCCTCTT CCTTCTCTTT 2460
GACCCCTGTG ACTCTTTCTG TAACTTTCCC AGTGACTTCC CCTAGCCCTG ACCACGCACT 2520
AGGCCTTGGT GACTTCCTGG GGCCAAGAAA CTAAGGAAAC TCGGCTTTGC AACAGβCATT 2580
ACTCGCCATT GATTGGTGCC CACCCAGGGC ACACTGTCGG AGTTCTATCA CTTGCTTGAC 2640
CCCTGGACCC ATAAACCAGT CCACTGTTAT ACCCGGGGCA CTCTAACCAT CACAATCAAT 2700
CAATCAAATT CCCTTAAATT TGTATGGCAC TGGAACTTTG GCAAAGCACT TTTGACAAGT 2760
TGTGTCTGAT TGβAGCTTCA TGATAGCCTT GTGACATCTT TAGβGCAGGA TTCTTATCCC 2820
CATTTTGCAG ATGAAAACCC TGAGTCACAG ATTTCTGTGG GACTGTGGAT CTCACTGGAA 2880
GCTATCCAAG AGCCCACTβT CACCTTCTAβ ACCACATGAT AGGGCTAGAC AGCTCAGTTC 2940
ACCATGATTC TCTTCTGTCA CCTCTGCTGG CACACCAGTG GCAAGGCCCA GAATGGCGAC 3000
CTCTCTTTAG CTCAATTTCT GGGCCTGAGG TGCTCAGACT GCCCCCAAGA TCAAATCTCT 3060
CCTGGCTβTA GTAACCCAβT GGAATGAATT TGGACATGCC CCAATGCTTC TATATGCTAA 3120
GTGAAATCTG TGTCTGTAAT TTGTTGGβee GTGGATAG6G TGGGGTCTCC ATCTACTTTT 3180
TGTCACCATC ATCTGAAATG GGGAAATATG TAAATAAATA TATCAGCAAA GC 3232
Seq ID NO: C199 DNA Sequence Nucleic Acid Accession #: NM_021990.1 Coding sequence: 1309..2490
1 11 21 31 41 51
G ICCAGAGCGT GIAGCCGCGAC CITCCGCGCAG GITGGTCGCGC CIGGTCTCCGC GIGAAATGTTG 60
TCCAAAGTTC TTCCAGTCCT CCTAGGCATC TTATTGATCC TCCAGTCGAG AACATGTATA 120
CAGAGAAGTC CTCAAATCAT AAGTGTACAG CTGATGAGTT GTCAAAAAAT GACCACAGCG 180
GTGTAAAGAA AGCCAAATCA AGGACCCGAA TGTGAGCAGG ACCTCAGAAG CCCCCTTTGT 240
CACTCCCTCC CAβCAAAGGC AGCACTATCC GGACTTCTAA CACCATCGGT GAGTTTCATA 300
CCTTGGCA6A TGβCCTTTAA CATTTTTGTT TAATTCAATT ATTCTTACTA ATCTTCTTCT 360
TTTTCTTGβC TGTGGTGCAT GGCTGTGGAG CTCAGGGTGG ACTCCTGTTG GGCAGCCAGT 420
TCCTGGATGG CTβTCTGTGG GTGGAGGACT CCTGCCTTTC CTGTTTAGAC ACCCACAAAG 480
GCTGCTCTTT AGCCTCCTTC CCTTCATCCC CTTCCCCTGC CCCCAGTGCA ACGAGTATTA 540
CACAACCAAC AAAACCβCAA AATATTGCCA CAATTTTCTβ GTCCTCTCTG GGAGAGβCCG 600
CTCTGGCTTT TCCTCTCAGC CCTGGCCCTC TGCCTGCTCC TCACTCCTGG TTGGTβCTGG 660
TCAGGCTGAC TAGAGGCCAA GGCGACCAAC ACTAGGCAAA CGCGGCCAGC GCTCAGACAT 720
AAATGCCCTC TTCATTTCAC GTGTAACATT CTTTTAAAAT CTAGGTCTTG GTTTTGTTGA 780
TTTTTTCTTA AATAAAAGAG TGATCATAAA AGAGGGACAG CATAGAAAGT CCCCAAAGAG 840
CAGCAAβGTT TTAAAGAAAT TCACAAGCCT AATCTGTCAC TGTCTTATAA TTTGCTATTA 900
CCAGTCACAA TTTAACTAGG TTTTGTGTTG AAAACTTGTT TTGGTTTGCT TCTGTCCCAA 960
GAGβCACTAG CTGGGGCCCC TACAGAGTGC AGGGCAGAGC TTCATTTTTC GTTTGAATGT 1020
TCTAGβGTCG AGGβACCTCA GACTGAATCA AAGAATGAAG CCTCTTCCCG TβATGTTGTC 1080
TATGGCCCCC AβCCCCAGCC TCTGGAAAAT CAGCTCCTCT CTGAGGAAAC AAAGTCAACT 1140
GAGACTGAβA CTβββAGCAG AGTTGGCAAA CTGCCAGAAG CCTCTCGCAT CCTGAACACT 1200
ATCCTGAGTA ATTATGACCA CAAACTGCGC CCTGGCATTG GAGAGAAGGC CACTGTGGTC 1260
ACTGTTGAGA TCTCCGTCAA CAGCCTTGGT CCTCTCTCTA TCCTAGACAT GGAATACACC 1320
ATTGACATCA TCTTCTCCCA GACCTGGTAC GACGAACGCC TCTGTTACAA CGACACCTTT 1380
GAGTCTCTTG TTCTGAATββ CAATGTGGTG AGCCAGCTAT GGATCCCGGA CACCTTTTTT 1440
AGβAATTCTA AβAβGACCCA CGAGCATGAG ATCACCATGC CCAACCAGAT GβTCCGCATC 1500
TACAAGGATG GCAAGGTGTT GTACACAATT AGGATGACCA TTGATGCCGG ATGCTCACTC 1560
CACATGCTCA GATTTCCAAT GGATTCTCAC TCTTGCCCTC TATCTTTCTC TAGCTTTTCC 1620
TATCCTGAGA ATGAGATGAT CTACAAGTββ GAAAATTTCA AGCTTGAAAT CAATGAGAAG 1680
AACTCCTGGA AGCTCTTCCA GTTTGATTTT ACAGGAGTGA GCAACAAAAC TGAAATAATC 1740
ACAACCCCAβ TTGGTGACTT CATGGTCATG ACGATTTTCT TCAATGTGAG CAGGCGGTTT 1800
GGCTATGTTG CCTTTCAAAA CTATGTCCCT TCTTCCGTGA CCACGATGCT CTCCTGGGTT 1860
TCCTTTTGGA TCAAGACAGA GTCTGCTCCA GCCCGGACCT CTCTAGGGAT CACCTCTGTT 1920
CTGACCATGA CCACGTTGGG CACCTTTTCT CGTAAGAATT TCCCGCGTGT CTCCTATATC 1980
ACACCCTTCG ATTTCTATAT CGCCATCTGC TTCGTCTTCT GCTTCTGCGC TCTGTTGGAG 2040
TTTGCTGTGC TCAACTTCCT GATCTACAAC CAGACAAAAG CCCATGCTTC TCCTAAACTC 2100
CβCCATCCTC GTATCAATAG CCGTGCCCAT GCCCGTACCC GTGCACGTTC CCGAGCCTCT 2160
GCCCGCCAAC ATCAGGAAGC TTTTGTGTGC CAGATTGTCA CCACTGAGGG AAGTGATGGA 2220
GAGGAGCGCC CGTCTTGCTC AGCCCAGCAG CCCCCTAβCC CAGGTAGCCC TGAGGGTCCC 2280
CGCAGCCTCT GCTCCAAGCT GGCCTGCTGT GAGTGGTGCA AGCGTTTTAA GAAGTACTTC 2340
TGCATGGTCC CCGATTβTβA GGGCAGTACC TGGCAGCAGG GCCβCCTCTG CATCCATGTC 2400
TACCGCCTGG ATAACTACTC GAGAGTTGTT TTCCCAGTGA CTTTCTTCTT CTTCAATGTG 2460
CTCTACTGGC TTGTTTGCCT TAACTTGTAG GTACCAGCTG GTACCCTGTG GGGCAACCTC 2520
TCCAGTTCCC CAGGAGGTCC AAGCCCCTTG CCAAGGGAGT TGGGGGAAAG CAGCAGCAβC 2580
AGCAGGAGCG ACTAGAGTTT TTCCTGCCCC ATTCCCCAAA CAGAAGCTTG CAGAGGGTTT 2640
GTCTTTGCTG CCCCTCTCCC CTACCTGGCC CATTCACTGA CTTTTCTCAG CAGACCATTT 2700
CAAATTATTA ATAAATGGGC CACCTCCCTC TTCTTCAAGG AGCATCCGTG ATGCTCAGTG 2760
TTCAAAACCA CAGCCACTTA GTGATCAGCT CCCTAAAACC ATGCCTAAGT ACAGGCGGAT 2820
TAGCTATCTT CCAACAATGC TGACCACCAG ACAATTACTG CATTTTTCCA GAAGCCCACT 2880
ATTGCCTTTG CAGTGCTTTC GGCCCAGTTC TGGCCTCAGC CTCAAAβTβC ACCGACTAGT 2940
TGCTTGCCTA TACCTGGCAC CTCATTAAGA TGCTGGGCAG CAGTATAACA GGAGGAAGAG 3000
ATCCCTCTCC TTTGGTCAGA TTATTATGTT CTCAGTTCTC TCTCCCTGCT ACCCCTTTCT 3060
CTGCAGATAG ATAGACACTG GCATTATCCC TTTAGGAAGA GGGGGGGGCA GCAAGAGAGC 3120
CTATTTGGGA CAGCATTCCT CTCTCTCTGC TGCTGTGACA TCTCCCTCTC CTTGCTGGCT 3180
CCATCTTTCG TCTβCACTAC CAATTCAATβ CCCTTCATCC AATGGGTATC TATTTTTGTG 3240
TGTGATTATA βTAACTACTC CCTGCTTTAT ATGCCACCCT CTTCCTTCTC TTTGACCCCT 3300
GTGACTCTTT CTCTAACTTT CCCAGTGACT TCCCCTAGCC CTGACCAGGG ACTAGGCCTT 3360
GGTGACTTCC TGGGGCCAAG AAACTAAGGA AACTCGGCTT TGCAACAGGG ATTACTCGCC 3420
ATTGATTGGT GCCCACCCAG GGCACACTβT CGGAGTTCTA TCACTTGCTT GACCCCTGGA 3480 CCCATAAACC AGTCCACTGT TATACCCGGG GCACTCTAAC CATCACAATC AATCAATCAA 3540 ATTCCCTTAA ATTTGTATGG CACTGGAACT TTGGCAAAGC ACTTTTGACA AGTTGTGTCT 3600 GATTGGAGCT TCATGATAGC CTTGTGACAT CTTTAGGGCA GGATTCTTAT CCCCATTTTG 3660 CAGATGAAAA CCCTGAGTCA CAGATTTCTG TGGGACTGTG GATCTCACTG GAAGCTATCC 3720 AAGAGCCCAC TGTCACCTTC TAGACCACAT GATAGGGCTA GACAβCTCAG TTCACCATGA 3780 TTCTCTTCTG TCACCTCTGC TβGCACACCA GTGGCAAGGC CCAGAATGGC GACCTCTCTT 3840 TAGCTCAATT TCTGGGCCTG AβGTGCTCAG ACTGCCCCCA AGATCAAATC TCTCCTGGCT 3900 GTAGTAACCC AGTGGAATGA ATTTGGACAT GCCCCAATGC TTCTATATGC TAAGTGAAAT 3960 CTGTGTCTGT AATTTGTTGG GGGGTGGATA GGGTβGβGTC TCCATCTACT TTTTGTCACC 4020 ATCATCTGAA ATGGGGAAAT ATGTAAATAA ATATATCAGC AAAGC 4065 Seq ID NO: C200 DNA Sequence
Nucleic Acid Accession ft: NM_021819.1 Coding sequence: 39..1619
60
120
Figure imgf001327_0001
180
GGGCTGGAAT ACCCTTCTGG AGCCATCATG GAGACGCCAT CCTGGGCCTG GAGGAAGTGC 240
GGCTGACGCC ATCCATGAGG AACCGGAGTG GCGCCGTGTG GAGCAGββCC TCTGTCCCCT 300
TCTCTGCCTG GGAAGTAGAG GTGCAAATGA GGGTGACGGG ACTGGGGCGC CGGGGAGCCC 360
ACGGCATGGC CGTGTGGTAC ACCCGGGGCA GGGGCCATGT AGGCTCTGTC CTTGGGGGGC 420
TGGCTTCGTG GGACGGCATC GGGATCTTCT TTGACTCTCC GβCAGAGGAT ACTCAGGACA 480
GTCCTGCCAT CCGTGTGCTG GCCAβCGACG GGCACATCCC CTCTGAGCAG CCTGGGGATG 540
GAGCTAGCCA AGGGCTGGGC TCCTGTCATT GGGACTTCCG GAACCGGCCA CACCCCTTCA 600
GAGCACGGAT CACCTACTGβ GβGCAGAGGC TGCGCATβTC CTTGAACAGT GGCCTCACTC 660
CCAGTCATCC AGGTGAGTTC TGTGTGGATG TCβGGCCCCT GCTTTTGGTC CCTGGAGGTT 720
TCTTTGGGGT CTCAGCAGCC ACCGGCACCC TGGCAGATGA TCATGATGTC CTGTCCTTCC 780
TβACCTTCAG CCTGAGTGAG CCCAGCCCAβ AGGTTCCCCC TCAGCCCTTC CTGGAGATGC 840
AGCAGCTCCG CCTGGCGAGG CAGCTGGAAG GGCTGTGGGC AAGGCTGGGC TTCβGCACCA 900
GGGAGGATGT AACTCCAAAA TCAGACTCTG AAGCTCAAGG AGAAGGGGAA AGGCTCTTTG 960
ACCTGGAGGA GACGCTGGGC AGACACCGCC GGATCCTGCA GGCTCTGCGG GGTCTCTCCA 1020
AGCA6CTG6C CCAGGCTGAG AGACAATGGA AGAAGCAGCT GβGGCCCCCA GGCCAAGCCA 1080
GGCCTGACββ AGGCTGGGCC CTGGATGCTT CCTGCCAGAT TCCATCCACC CCAGGGAGGβ 1140
GTGGCCACCT CTCCATCTCA CTCAATAAGG ACTCTGCCAA GGTCGGTGCC CTGCTCCATG 1200
GACAGTGGAC TCTGCTCCAG GCCCTβCAAβ AGATGAGGGA TGCAGCTGTC CGCATGGCTG 1260
CAGAAGCCCA GGTCTCCTAC CTCCCTCTGG GCATTGAGCA TCATTTCTTA GAGCTGGACC 1320
ACATCCTGGG CCTCCTGCAG GAGGAGCTTC GGGGCCCGGC GAAβGCAGCA GCCAAGGCCC 1380
CCCGCCCACC TGGCCAGCCC CCAAGGGCCT CCTCGTGCCT GCAGCCTGGC ATCTTCCTGT 1440
TCTACCTCCT CATTCAGACT GTAGGCTTCT TCGGCTACGT GCACTTCAGG CAGGAGCTGA 1500
ACAAGAGCCT TCAGGAGTGT CTGTCCACAG GCAGCCTTCC TCTGGGTCCT GCACCACACA 1560
CCCCCAGGGC CCTGGGGATT CTGAGGAGGC AGCCTCTCCC TGCCAGCATG CCTGCCTGAC 1620
CCACCTCAGA GCCTGCTTTG CATCACTCGβ AAβCAGGCAG TGTCTTGGGT GGGGGCTTGG 1680
TCAGTATCCT CTCCGTCTGG GTGCCCAGCT CCCACGCACA CCTGAβCTTT CGGCATGCTC 1740
CCACCTCGTT AAAGGTGATT TCCCTCTCAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 1800
A 1801
Seq ID NO : C201 DNA Sequence
Nucleic Acid Accession # : XM_117036 .1
Coding sequence : 25. .495
1 11 21 31 41 51 1 1 | 1 I 1 | 1 | 1 | 1
AGCCAAGAGA GGGGGGACAG ACAGATGGAA AGACGGACAC GGGGAGCTCT GGGGAGCAGG 60
CGGCCCCCAC CCCCACTTCC AGCTCTGAGA CATTTGTGCA CAGGCCTGCA GGCGGCTGββ 120
ATGGCCTGGC CGGGCACβCT CTGGAGACAC ACATGCCAAG GCAGGGCCNG GGCAGCCGAG 180
GGCCCGTGGG GGCTGTTCCG ACCACACAGG TGCCCGAGββ AGβCAGGGCA GGCCCCGGTG 240
GGACCCAGCC CCGAAACGCA GGGTGTCGGG CACGTTTGCA GCCGCGCTCG CGTGTCGGTG 300
GATGAGCGGG AACCGGββββ CGGCGCCTAC GCAATGCACG TTACGCCGCG GTCβAAGGGβ 360
TGTCACCGCC ACAGCGGCCG CACCGTGCGT GβCTCTGTTT CCTGGAAACβ TCCAβAACAG 420
GCAGCCCCCG AGACAGGGAG GGGCCCAGCβ GTCGCCAGGG GAA6TCGGGA TGGGAATGAG 480
TGCGGATGGG GCTGAGGTTC TTCCTGAAGG ATGAATGCTC TGAAACTGTG AATAGACACA 540
CGβAACTGTG CACGTTCACN GGTGAACCGT GTGGGGAGTG AATCCATCTC AACAGAGCTG 600
TTACACAGTG AACAAGAβCA CGANGGGTGG AGGCCNCTTG TCTGCTCCTG CAGATCGA6C 660
CGGCTGCTCA GAGCCGGGAG ATGGCCACTC AGCTCCTTTA ACTG 704
Seq ID NO: C202 DNA Sequence
Nucleic Acid Accession # : XM_167803 .2
Coding sequence : 1162 . .1488
60
120
Figure imgf001327_0002
180
GAGGGCAGCG ACCCCGAGGC CTCGTGβACG TGGGAGAGAG TGTββTGGGA AGTCTTGAGC 240
GGAGGAGGGG ATCTGCCCTT CTCCACTCCT CTCTTGGATC CGCCTCGGTT TCCTGTCCCC 300
CCACCACCCG CCTGCCCCGC GβAAGACCGC CCAGTGAGCC AGCCCCCACC TTCCAGGCGC 360
CTTCGCCCTG GGGATCCAAC CAACTTβTAT CGAGTGGGCG GGGCAACGGC TCCCCATTTT 420
TCCCGAGCCC CGCCCACAGA GCTCTTAGCC AATCCTATGC AGAGAGCATC TCCTGGCAGG 480
GGTCTCTTCC CAACCAβACC CCACCCAGGC ACATTAGCGA CCAGGCTTGG GCTTCCCCAG 540
CGCCCCACCA CCACCACGTG CAGCTGGAGC TCTGGGATGC TATGTTGGGG CGGCAAGCGG 600
TGGGCCGAGG GCCGGGTAGG CTAGCACGGG AGGTAAGGGT GGTATGGGAT GGGGCβββGG 660
CGGTCTAβGG CAATAGGAGA GCAGAGAATG GGGGAACTTG AGGGTGGGGG GAGGGCACCG 720 GAGCCTTGCC ACCATCCCAG GACTTTGGGC AAGTCACCCG CACTCCCTGG GCCTCGGTTT 780
CCCCATCTGT AAAATGATGG TAATAATAGT TCACCTACCT CATAGGGGAG GTTGTGAGGC 840
CACCATCACC TGACCTGGGG GTCAACβCAG GAGGACTCCG AAGGTGCTAC CCGTGAGCAA 900
AGTGTAATTA CCGAATCCTG ACTGCAAGGC CCACCTGCCC CTCCCCCACA GAGCCTCCAG 960
AGCTAGCTβA GGCCAACGCA GGCCCATCCG TCTCTTCACT CTGTCGCAGG CCCTTTCATG 1020
GGCTTCGTCT GCCATCTTTG TGGGTGCCCT AGACTTAGTC CTTATCTTGT CCTββTTTCC 1080
TTTCTTGTGA CCATCTCCCC ATGAAAGTGC TGTACAAATT CCACCCGCCC CAGGACCCCC 1140 βCACCTGCCC TCTGGCACCA GATGCCAGGβ AAGGGACAGA GGAAAACAGC CACAAACAAG 1200
CCAGGGGGGC TCCCCGGAGC CCCAGGGGTG GGGATTβGTG GCCACTGTTT CTATβTTCTT 1260
GAGTGCAAGT GTTTTATAAA AAATAAAACA AAAACCCACC ATCACAAAAA AAAAAATTTT 1320
GCAGCGAAGA GAAATGAAGA AAAACTGAAG AAAAAAAAAA AACAGGAAAA AAAGAACCAT 1380
ACAAAATTTT TCCACCACAC ATACCCTCTA AGCCAGCAAG ATTTCCTCTT TGCAAAATCA 1440
TATTTTTGTG GβAATGGGCC CTGCTTTTTG TGGCAAGGCC TGTTCTGATT AATAAAGGAT 1500
CGTGAAAAAG T 1511
Seq ID NO: C203 DNA Sequence
Nucleic Acid Accession ff: NM_024780.1
Coding sequence: 31..1023
1 11 21 31 41 51 1 1 I 1 | 1 | 1 I 1 I 1 ATTAATCTGG CCGTGCCATG CATCTACTCC ATGTTCAGGC TTGTCGAGAβ GTACGAGATG 60
CCACGGCACG AAGTCTACGT TCTCCTGATC CGAAACATCT TTTTGAAAAT ATCAATCATT 120
GGCATTCTTT GTTACTATTG GCTCAACACC GTGGCCCTGT CTββTβAAGA GTGTTGGGAA 180
ACCCTCATTG GCCAGGACAT CTACCGβCTC CTTCTGATGG ATTTTGTGTT CTCTTTAGTC 240
AATTCCTTCC TGβeeβAβTT TCTGAGGAGA ATCATTG6GA TGCAACTGAT CACAAGTCTT 300
GGCCTTCAGG AGTTTGACAT TGCCAGGAAC GTTCTAGAAC TGATCTATGC ACAAACTCTG 360
GTGTGGATTG GCATCTTCTT CTGCCCCCTG CTGCCCTTTA TCCAAATGAT TATGCTTTTC 420
ATCATGTTCT ACTCCAAAAA TATCAGCCTG ATGATGAATT TCCAβCCTCC GAGCAAAGCC 480
TGGCGGGCCT CACAGATGAT GACTTTCTTC ATCTTCTTGC TCTTTTTCCC ATCCTTCACC 540
GGGGTCTTGT GCACCCTGGC CATCACCATC TGGAGATTGA AGCCTTCAGC TGACTGTGGC 600
CCTTTTCGAG GTCTGCCTCT CTTCATTCAC TCCATCTACA GCTGGATCGA CACCCTAAGT 660
ACACGGCCTG GCTACCTGTG GGTTGTTTGG ATCTATCGGA ACCTCATTGG AAGTGTGCAC 720
TTCTTTTTCA TCCTCACCCT CATTGTGCTA ATCATCACCT ATCTTTACTG GCAGATCACA 780
GAGGβAAGGA AGATTATGAT AAGGCTGCTC CATGAGCAGA TCATTAATGA GGGCAAAGAT 840
AAAATGTTCC TGATAGAAAA ATTGATCAAβ CTGCAGGATA TββAGAAGAA AGCAAACCCC 900
AGCTCACTTG TTCTGGAAAG GAGAGAββTG GAGCAACAAG GCTTTTTβCA TTTGGGGGAA 960
CATGATGGCA GTCTTGACTT GCGATCTAGA AGATCAGTTC AAGAAGGTAA TCCAAGGGCC 1020
TGATGACTCT TTTGGTAACC AGACACCAAT CAAATAAGGG GAGGAβACGA AAATGGAATG 1080
ATTTCTTCCA TGCCACCTGT GCCTTTAGGA ACTGCCCAGA AGAAAATCCA AGβCTTTAGC 1140
CAGGAGCGGA AACTGACTAC CATGTAATTA TCAAAGTAAA ATTGGβCATT CCATGCTATT 1200
TTTAATACCT GGATTGCTGA TTTTTCAAGA CAAAATACTT GGGGTTTTCC AATAAAGATT 1260
GTTGTAATAT TGAAATGAGC CTACAAAAAC CTAGGAAGAG ATAACTAGGβ AATAATGTAT 1320
ATTATCTTCA AGAAGTGTGT GCAGGAATGA TTGGTTCTTA GAAATCTCTC CTGCCAGACT 1380
TCCCAGACCT GGCAAAGGTT TAGAAACTGT TGCTAAGAAA AGTGGTCCAT CCTGAATAAA 1440
CATGTAATAC TCCAGCAGGG ATATGAAβCC TCTGAATTGT AGAACCTGCA TTTATTTGTG 1500
ACTTTGAACT AAAGACATCC CCCATGTCCC AAAGGTGGAA TACAACCAGA GGTCTCATCT 1560
CTGAACTTTC TTGCCTACTβ ATTACATGAG TCTTTGGAGT CGGGGATGGA GGAGGTTCTG 1620
CCCCTGTGAG βTβTTATACA TGACCATCAA AGTCCTACGT CAAGCTAGCT TTGCAβTGGC 1680
AGTACCGTAG CCAATGAGAT TTATCCGAGA CGCβATTATT GCTAATTGGA AATTTTCCCA 1740
ATACCCCACC GTGATGACTT GAAATATAAT CAGCβCTGGC AATTTTTGAC AGTCTCTACG 1800
GAGACTGAAT AAG 1813
Seq ID NO: C204 Protein Sequence Protein Accession ff: Eos sequence
11 21 31 41 51
I I I I I
AGCGGGGTTA GATGCAGββA GTTATGTTGT GATTTGTGTA GGGGTGGCTT TGGTGAGCTC 60 ATCCTGGCAT TTTAAAAATA ATGTGAATGG TGTATCCCTT TGTGATCATC ATCACTTTTT 120 CCCTGCGAGT CCCAATCAAT GCGGGTGTGA CTGCTGTATG AAGTCTCAGG AAGCCCACCC 180 CAGTGGAGAA GAAGGCTTGC AGGAGGCAGG AGATβCTGTC CGATGACCAC GTGAATGAAA 240 TCATCATACA GGTTGAGAAT GTTTCCTCTG GGGTCCAAAG CCACCCATCC TCAAATCAGA 300 TTTTTCAAGA AAAGGTGCTG CTAGACTCAA GCATCAACAT GGTTTTGTCA ATATCTGACA 360 TTGATGTβAT AGACTCTCAG ACAGTCAGCA AAAGGAATGA CCAAAAGGGT AACCAGGTGC 420 TGCGGTTTTC AACATCTTTG AATGAGTCGA TGTCTCAGAC CCTTCATAGC CTAGAATGCA 480 TGGGCATAGA CACTCCTGGT TCTTCACATG AAACTGTTCA AGGACAGAAG TTAATCGCAT 540 CCCTTATACC CATGACATCC AGAGACAGAA TTAAAGCCAT CAGGAACCAG CCAAGGACCA 600 TGGAAGAGAA AAGGAACCTT AβGAAAATAG TTGACAAAGA AAAAAGCAAA CAGACCCATC 660 GTATCCTTCA GCTCAATTGC TGTATTCAGT GTCTGAACTC CATTTCCCGG GCTTATCGβA 720 GATCCAAGAA CAGCCTGTCG GAAATTCTGA ATTCCATCAG CCTGTGGCAG AAGACGCTGA 780 AGATGATTGG AβGCAAGTTT GGAACCAGCG TCCTCTCCTA TTTCAACTTT CTGAβATGGC 840 TTTTGAAGTT CAACATTTTC TCATTCATCC TGAACTTCAG CTTCATCATA ATCCCTCAGT 900 TTACCGTCGC CAAAAAGAAC ACCCTCCAGT TCACTGGGCT GGAGTTTTTC ACTGββGTGG 960 GTTATTTTAG GβACACAβTG ATGTACTATG GCTTTTACAC CAATTCCACC ATCCAGCACG 1020 GGAACAGCGG GGCATCCTAC AACATGCAGC TGGCCTACAT CTTCACAATC GGAGCATGCT 1080 TGACCACCTG CTTCTTCAGT TTGCTCTTCA GCATGGCCAA GTATTTCCGG AACAACTTCA 1140 TTAATCCCCA CATTTACTCC GGAGββATCA CCAAGCTGAT CTTTTGCTGG GACTTCACTG 1200 TCACTCATGA AAAAGCTGTG AAGCTAAAAC AGAAGAATCT TAGCACTGAG ATAAGGGAGA 1260 ACCTGTCAGA GCTCCGTCAG GAGAATTCCA AGTTGACGTT CAATCAGCTG CTGACCCGCT 1320 TCTCTGCCTA CATGGTAGCC TGGGTTGTCT CTACAGGAGT GGCCATAGCC TGCTβTβCAG 1380 CCGTTTATTA CCTGGCTGAG TACAACTTAβ AGTTCCTGAA GACACACAGT AACCCTGGGG 1440 GGGTGCTGTT ACTGCCTTTC GTTGTGTCCT GCATTAATCT GGCCGTGCCA TGCATCTACT 1500 CCATGTTCAG GCTTGTGGAG AGβTACGAGA TGCCACGGCA CGAAGTCTAC GTTCTCCTGA 1560 TCCGAAACAT CTTTTTGAAA ATATCAATCA TTGGCATTCT TTGTTACTAT TGGCTCAACA 1620
CCGTGGCCCT GTCTGGTβAA GAGTGTTβGG AAACCCTCAT TGGCCAGGAC ATCTACCGGC 1680
TCCTTCTGAT GGATTTTGTG TTCTCTTTAG TCAATTCCTT CCTGGββGAG TTTCTGAGGA 1740
GAATCATTGG GATGCAACTG ATCACAAGTC TTGGCCTTCA GGACTTTGAC ATTGCCAGGA 1800
ACGTTCTAGA ACTGATCTAT GCACAAACTC TGGTGTGGAT TGGCATCTTC TTCTGCCCCC 1860
TGCTGCCCTT TATCCAAATG ATTATGCTTT TCATCATGTT CTACTCCAAA AATATCAGCC 1920
TGATGATGAA TTTCCAGCCT CCGAGCAAAG CCTGGCGβGC CTCACAGATG ATGACTTTCT 1980
TCATCTTCTT GCTCTTTTTC CCATCCTTCA CCGGGGTCTT GTGCACCCTG βCCATCACCA 2040
TCTG6AGATT GAAGCCTTCA GCTGACTGTG GCCCTTTTCG AGGTCTGCCT CTCTTCATTC 2100
ACTCCATCTA CAGCTGGATC GACACCCTAA GTACACGGCC TGGCTACCTG TGGGTTGTTT 2160
GGATCTATCG GAACCTCATT GGAAGTGTGC ACTTCTTTTT CATCCTCACC CTCATTGTGC 2220
TAATCATCAC CTATCTTTAC TGGCAGATCA CAGAGGGAAG GAAGATTATβ ATAAGGCTGC 2280
TCCATGAGCA GATCATTAAT GAGGGCAAAG ATAAAATGTT CCTCATA6AA AAATTGATCA 2340
AGCTGCAGGA TATGGAGAAG AAAGCAAACC CCAGCTCACT TGTTCTGGAA AGβAGAGAGG 2400
TGβAGCAACA AGGCTTTTTG CATTTGGGGβ AACATGATGG CAGTCTTGAC TTGCGATCTA 2460
GAAGATCAGT TCAAGAAGGT AATCCAAGGG CCTGATGACT CTTTTG6TAA CCAGACAGCA 2520
ATCAAATAAG GGGAGGAGAY GAAAATGGAA TGATTTCTTC CATGCCACCT GTGCCTTTAG 2580
GAACTGCCCA GAAGAAAATC CAAββCTTTA GCCAGGAGCG GAAACTGACT ACCATGTAAT 2640
TATCAAAGTA AAATTGGGCA TTCCATβCTA TTTTTAATAC CTGGATTGCT GATTTTTCAA 2700
GACAAAATAC TTGGGGTTTT CCAATAAAGA TTGTTGTAAT ATTGAAAWRA RMMWAMAAAA 2760
ACCTAGGAAG AGATAACTAG GGAATAATGT ATATTATCTT CAAGAAGTCT GTβCAββAAT 2820
GATTGGTTCT TAGAAATCTC TCCTGCCAGA CTTCCCAGAC CTGGCAAAβe TTTAGAAACT 2880
GTTGCTAAGA AAAGTGGTCC ATCCTGAATA AACATGTAAT ACTCCAβCAβ GGATATGAAG 2940
CCTCTGAATT GTAGAACCTG CATTTATTTG TGACTTTGAA CTAAAGACAT CCCCCATGTC 3000
CCAAAGGTGG AATACAACCA GAGGTCTCAT CTCTGAACTT TCTTGCGTAC TGATTACATG 3060
AGTCTTTGβA GTCGGGGATβ GAGGAGGTTC TGCCCCTGTG AGGTGTTATA CATGACCATC 3120
AAAGTCCTAC GTCAAGCTAG CTTTGCAGTG GCAGTACCGT AGCCAATGAG ATTTATCCGA 3180
GACGCGATTA TTGCTAATTG GAAATTTTCC CAATACCCCA CCGTGATGAC TTCAAATATA 3240
ATCAGCGCTG GCAATTTTTG ACAGTCTCTA CGGAGACTGA ATAAG 3285
Seq ID NO: C205 DNA Sequence
Nucleic Acid Accession ft :• NM.002250.1
Coding sequence: 397..1680
11 21 31 51
GTCCTTCGGT GTCTGGGTGT GGTGAGTAGA GGTGTGTGTC ACAAAGTACA GACCATTβTβ 60
TGTGACAAAG CCCATCGTGT GTCTGTGTGT GTCTTTATCC ACGTGGATGβ ACCTCTCTTT 120
CTTGCTCTGC CCCAAGACAC ACCCTAβCCC CTCCTTATTC TCAAAAβGGG GAGCTGGββA 180
GCCTCCCCCT ACCCTGGGGC GTCCCCTGCC CCTCCCCGCC CTGCCTGGCC βTCACCACTC 240
CCCAGAGGGC ACAGGGCTCT GCTGTGCCTC AGAGCAAAAG TCCCAGAGCC AGCAGAGCAG 300
GCTGACGACC TGCAAGCCAC AGTGGCTGCC CTGTGCGTGC TGCGAGGTGG GGGACCCTGβ 360
GCAGGAAGCT GGCTGAGCCC CAAGACCCCG GGGGGCATGG GCGGGGATCT GGTGCTTCGC 420
CTGGGGGCCT TGAGACGCCG AAAGCGCTTG CTGGAβCAGG AGAAGTCTCT GGCCGGCTGG 480
GCACTGGTGC TGGCAGGAAC TCGCATTGGA CTCATGGTGC TGCATβCAGA GATGCTGTGG 540
TTCGGGGGGT GCTCβTβββC GCTCTACCTG TTCCTGGTTA AATCCACGAT CAGCATTTCC 600
ACCTTCTTAC TCCTCTβCCT CATCGTGGCC TTTCATGCCA AAGAGGTCCA GCTGTTCATG 660
ACCGACAACG GGCTGCGGGA CTGGCGCGTG GCGCTGACCG GGCGGCAGGC GGCGCAGATC 720
GTGCTGGAGC TGGTGGTGTG TGGGCTGCAC CCGGCGCCCβ TGCGGGGCCC GCCGTGCGTG 780
CAGGATTTAG GGGCGCCGCT GACCTCCCCG CAGCCCTGGC CGGGATTCCT GGGCCAAGGG 840
GAAβCeCTGC TGTCCCTGGC CATGCTGCTG CGTCTCTACC TGGTGCCCCG CβCCβTβCTC 900
CTGCGCAGCG GCGTCCTGCT CAACGCTTCC TACCGCAGCA TCGGCGCTCT CAATCAAGTC 960
CGCTTCCGCC ACTGGTTCGT GGCCAAGCTT TACATGAACA CGCACCCTGG CCGCCTGCTG 1020
CTCGGCCTCA CGCTTGGCCT CTGGCTGACC ACCGCCTGGG TGCTGTCCGT GGCCβAGAGG 1080
CAGGCTGTTA ATGCCACTGG GCACCTTTCA GACACACTTT GGCTGATCCC CATCACATTC 1140
CTGACCATCG GCTATGGTGA CGTGGTGCCG GGCACCATGT GGGGCAAGAT CGTCTGCCTG 1200
TGCACTGGAG TCATGββTβT CTGCTGCACA GCCCTGCTGG TGGCCGTGGT GGCCCGGAAG 1260
CTGGAGTTTA ACAAGGCAGA GAAGCACGTG CACAACTTCA TGATGGATAT CCAGTATACC 1320
AAAGAGATGA AGGAGTCCGC TGCCCGAGTG CTACAAGAAG CCTGβATGTT CTACAAACAT 1380
ACTCGCAGGA AGGAGTCTCA TGCTGCCCGC AGGCATCAGC GCAAGCTGCT GGCCGCCATC 1440
AACGCGTTCC GCCAGGTGCG GCTGAAACAC CGGAAGCTCC GGGAACAAGT GAACTCCATG 1500
GTCGACATCT CCAAGATGCA CATGATCCTG TATGACCTGC AGCAGAATCT GAGCAGCTCA 1560
CACCGGGCCC TGGAGAAACA GATTGACACG CTGGCGGGGA AGCTGGATGC CCTGACTGAG 1620
CTGCTTAGCA CTGCCCTGGG GCCGAGGCAG CTTCCAβAAC CCAGCCAGCA GTCCAAβTAG 1680
CTGGACCCAC GAGGAGGAAC CAGGCTACTT TCCCCAβTAC TGAβGTGGTG GACATCGTCT 1740
CTGCCACTCC TGACCCAGCC CTGAACAAAG CACCTCAAGT GCAAGGACCA AAGGGGGCCC 1800
TGGCTTGGAG TGGGTTGGCT TGCTGATGGC TGCTGGAGGG GACGCTβGCT AAAGTGGGTA 1860
GGCCTTGGCC CACCTGAGβC CCCAGGTGGG AACATGGTCA CCCCCACTCT GCATACCCTC 1920
ATCAAAAACA CTCTCACTAT GCTGCTATGG ACGACCTCCA GCTCTCAGTT ACAAGTβCAG 1980
GCGACTGGAG GCAβGACTCC TGGGTCCCTG βGAAAGAGGG TACTAGGGGC CCGGATCCAG 2040
GATTCTGGGA GGCTTCAGTT ACCGCTGGCC GAGCTGAAGA ACTGGGTATG AGGCTGGGGC 2100
GGGGCTGβAG GTGGCGCCCC CTGGTGGGAC AACAAAGAGG ACACCATTTT TCCAGAGCTG 2160
CAGAGAGCAC CTGGTGGGGA GGAAGAAGTG TAACTCACCA GCCTCTGCTC TTATCTTTGT 2220
AATAAATGTT AAAGCCAG 2238
Seq ID NO: C206 DNA Sequence
Nucleic Acid Accession ff: NM_025257.1
Coding sequence: 1..2139
1 11 21 31 41 51
I I I I I I
ATGGGGGGAA AGCAGCGGGA CGAGGATGAC GAGGCCTACG GGAAGCCAGT CAAATACGAC 60 CCCTCCTTTC GAGGCCCCAT CAAGAACAβA AGCTGCACAG ATGTCATCTβ CTGCGTCCTC 120 TTCCTGCTCT TCATTCTAGG TTACATCGTG GTGGGGATTG TGGCCTGGTT GTATGGAGAC 180 CCCCGGCAAG TCCTCTACCC CAGGAACTCT ACTGGGGCCT ACTGTGGCAT GGGGGAGAAC 240
AAAGATAAGC CGTATCTCCT GTACTTCAAC ATCTTCAGCT GCATCCTGTC CAGCAACATC 300
ATCTCAGTTG CTGAGAACGG CCTACAGTGC CCCACACCCC AGβTβTGTGT GTCCTCCTGC 360
CCGGAGGACC CATGGACTGT GGGAAAAAAC GAGTTCTCAC AGACTGTTGβ GGAAGTCTTC 420
TATACAAAAA ACAGGAACTT TTGTCTGCCA βGGGTACCCT βGAATATGAC GGTGATCACA 480
AGCCTGCAAC AGGAACTCTG CCCCAGTTTC CTCCTCCCCT CTGCTCCAGC TCTGGGACGC 540
TGCTTTCCAT GGACCAACAT TACTCCACCG GCGCTCCCAG GGATCACCAA TGACACCACC 600
ATACAGCAGG GβATCAβCCG TCTTATTGAC AGCCTCAATG CCCGAGACAT CAGTGTTAAG 660
ATCTTTGAAG ATTTTGCCCA GTCCTGGTAT TGGATTCTTG TTGCCCTGGβ GGTGGCTCTG 720
GTCTTGAGCC TACTGTTTAT CTTGCTTCTG CGCCTGGTCG CTβGGCCCCT GGTGCTGGTG 780
CTGATCCTGG GAGTGCTGGG CGTGCTGβCA TATGGCATCT ACTACTGCTG GGAGGAGTAC 840
CGAGTGCTGC GGGACAAGGG CGCCTCCATC TCCCAGCTGG GTTTCACCAC CAACCTCAGT 900
GCCTACCAGA GCGTGCAGGA GACCTGGCTG GCCGCCCTGA TCGTGTTGGC GGTGCTTGAA 960
GCCATCCTGC TGCTGGTGCT CATCTTCCTG CGGCAGCGGA TTCGTATTGC CATCGCCCTC 1020
CTGAAGGAGG CCAβCAAGGC TGTGGGACAG ATGATGTCTA CCATGTTCTA CCCACTGGTC 1080
ACCTTTGTCC TCCTCCTCAT CTGCATTGCC TACTGGGCCA TGACTGCTCT GTATCCTCTG 1140
CCCACGCAGC CAGCCACTCT TGGATATGTG CTCTGGGCAT CCAACATCAG CTCCCCCGGC 1200
TGTGAGAAAG TGCCAATAAA TACATCATGC AACCCCACGG CCCACCTTGT GAACTCCTCG 1260
TGCCCAGGGC TGATGTGCGT CTTCCAGGGC TACTCATCCA AAGGCCTAAT CCAACGTTCT 1320
GTCTTCAATC TGCAAATCTA TGGGGTCCTG GGβCTCTTCT GGACCCTTAA CTGGGTACTG 1380
GCCCTGGGCC AATGCGTCCT CGCTGβAGCC TTTGCCTCCT TCTACTGGGC CTTCCACAAG 1440
CCCCAGGACA TCCCTACCTT CCCCTTAATC TCTGCCTTCA TCCGCACACT CCGTTACCAC 1500
ACTGGGTCAT TGGCATTTGG AGCCCTCATC CTGACCCTTG TGCAGATAGC CCGGGTCATC 1560
TTGGAGTATA TTGACCACAA GCTCAGAGGA GTGCAGAACC CTGTAGCCCG CTGCATCATG 1620
TGCTGTTTCA AGTGCTGCCT CTGGTGTCTG GAAAAATTTA TCAAGTTCCT AAACCGCAAT 1680
GCATACATCA TGATCGCCAT CTACGGβAAG AATTTCTGTG TCTCAGCCAA AAATGCGTTC 1740
ATGCTACTCA TGCGAAACAT TGTCAGGGTG GTCGTCCTGG ACAAAGTCAC AGACCTGCTG 1800
CTGTTCTTTG GGAAGCTGCT GGTGGTCGGA GGCGTGGGGG TCCTGTCCTT CTTTTTTTTC 1860
TCCGGTCGCA TCCCGGGGCT GββTAAAGAC TTTAAGAGCC CCCACCTCAA CTATTACTGG 1920
CTGCCCATCA TGACCTCCAT CCTGGGGGCC TATGTCATCG CCAGCGGCTT CTTCAGCGTT 1980
TTCGGCATGT GTGTGGACAC GCTCTTCCTC TGCTTCCTGG AAGACCTGGA GCGGAACAAC 2040
GGCTCCCTCG ACCGGCCCTA CTACATGTCC AAGAGCCTTC TAAAGATTCT GGGCAAGAAG 2100
AACGAGGCGC CCCCGGACAA CAAGAAGAGG AAGAAGTGAC AGCTCCGGCC CTGATCCAGG 2160
ACTGCACCCC ACCCCCACCG TCCAGCCATC CAACCTCACT TCGCCTTACA GGTCTCCATT 2220
TTGTGGTAAA AAAAGGTTTT AGGCCAGGCG CCGTGGCTCA CGCCTGTAAT CCAACACTTT 2280
GAGAGGCTGA GGCGGGCGGA TCACCTGAGT CAGGAGTTCG AGAGCAGCCT GGCCAACATG 2340
GTGAAAC 2347 Seq ID NO: C207 DNA Sequence Nucleic Acid Accession ft: NM_016180.1 Coding sequence: 26..1618
11 21 31 41 51
I I I I
CAGGAAGGTT CCTCTCCCAG TGGCCATGGG TAGCAACAGT GGGCAGGCTG GCCGCCACAT 60 CTATAAATCC CTAGCTGATβ ATGGCCCCTT TGACTCTGTG GAβCCGCCTA AAAGACCCAC 120 CAGCAGACTC ATCATGCACA GCATGGCCAT GTTCGGAAGA GAGTTCTGCT ACGCGGTGGA 180 GGCAGCGTAT GTGACCCCAG TCCTGCTCAG CGTAGGTCTG CCCAGCAGCC TGTACAGCAT 240 TGTGTGGTTC CTCAGCCCCA TCCTGGGATT CCTGCTCCAG CCCGTβGTCG GATCGGCCAG 300 CGACCACTGC CGGTCCAGGT GGGGCCGCCG GAGACCCTAC ATCCTCACCC TGGGAGTCAT 360 GATGCTCGTG GGCATGGCTC TGTACCTCAA TGGGGCTACT GTTGTAGCAG CTTTGATTGC 420 TAACCCAAGG AGGAAGCTGG TTTGGGCCAT AAGTGTCACC ATGATAGGTG TCGTTCTCTT 480 TGATTTTGCT βCCGACTTCA TTGATGGGCC CATCAAAGCC TACTTATTTG ATGTCTGCTC 540 CCATCAGGAC AAGGAGAAGG GCCTCCACTA CCATGCCCTC TTCACAGGTT TTGGAGGTGC 600 CCTβββTTAC CTTTTGGGTG CTATAGACTG GGCCCATCTG GAGCTGGGAA GACTGTTGGG 660 TACAGAATTC CAGCTCATGT TCTTCTTCTC TGCATTGGTG CTCACTTTGT GTTTTACTGT 720 TCATCTGTβC AGTATCTCTG AAGCCCCACT TACAGAGGTT GCAAAGGGCA TTCCCCCACA 780 GCAAACCCCT CAGGACCCTC CATTGTCATC AGATGGAATG TACGAGTATG GTTCTATCGA 840 GAAAGTTAAA AATGGTTACG TAAATCCAGA GCTGGCAATG CAGβGAGCAA AAAACAAAAA 900 TCATGCTGAA CAGACTCGCA GGβCAATGAC ATTAAAGTCA CTGCTGAGAG CACTGGTGAA 960 CATGCCTCCT CACTACCGCT ACCTTTGCAT CAGCCACCTC ATTGGATGGA CGGCCTTCCT 1020 GTCCAACATG CTGTTCTTCA CAGATTTCAT GGGCCAGATT GTGTACCGCG GGGATCCCTA 1080 TAGTGCACAC AACTCCACAG AGTTTCTCAT CTACGAAAGA GGAGTCGAGG TTGGATGTTG 1140 GGGCTTCTGC ATCAACTCCG TGTTTTCCTC ACTTTATTCT TACTTTCAGA AAGTTTTGGT 1200 ATCCTACATT GGATTAAAGβ GTCTTTACTT CACGGGATAT TTGCTGTTTG GCCTGGGGAC 1260 GGGATTTATT GGGCTCTTCC CGAATGTCTA CTCCACCCTG GTCCTGTGCA GCCTGTTTGG 1320 TGTAATGTCC AGCACCCTGT ACACTGTCCC CTTTAACCTC ATTACTGAGT ACCACCGCGA 1380 GGAAGAAAAG GAGAG6CA6C AGGCCCCAGG AGGGGACCCA GACAACAGCG TGAGAβGGAA 1440 GGGCATGGAC TGCGCCACCC TCACATGCAT GGTGCAGCTG GCTCAGATCC TGGTCGGAGG 1500 TGGCCTGGGC TTTCTGGTCA ACACAGCCGβ GACCGTTGTC GTCGTGGTGA TCACAGCGTC 1560 TGC6GTCGCA CTGATAGGCT GTTGCTTTGT CGCTCTCTTT GTTAGATATG TGGATTAGGT 1620 CAATAAAGAG ACAATGACCC TAAAAAAAAA 1650
Seq ID NO: C208 DNA Sequence
Nucleic Acid Accession ff: NM.003273.1
Coding sequence: 255..2024
11 31 41 51
I I I I
CGCCGCGGGG CCGGATCCTC CCCCCGGCCG AGTCCATCTC CTGGβAAATG GGGCGGACAG 60 TGTTTCCTTG ACTGACTATT GTGAβCGCCC TCTCTCTCCG GCGGAGCGGA GACCATGGCC 120 CCCACTCAGG CCCCCGGGCC CCCCTCGAAT TCGGAGGGCC CCTGGGTAAT GGGGCAGAGA 180 GATGGGACCT GGGGCAAAGG CTAAGCGAAβ GAGAGCTGGA GCGGGTCAAC TAAGAGCGGG 240 GβCGAGATCT GAGGATGGAA GGCTTTGGGG GTGTCGGAGG CAGAGGGACC CGGGβGTTTG 300 CAGCGAAGGG TGTCTGGAGA GGGAGAGCTG AGGAGGGGCC GGTTCTGGGG GCTGCAGAAC 360
GGGGATTTAT GGTGTCGACT GGGAGCAGGA GGAGGGTCTT CGAGGGGCCT GβGGGCGGGG 420
GACTAAGATG GACβCCTGGG AAGGGAACTG GGAGGCAGCG GGGTGCCTGG GGGCCGAGβG 480
CTGAGGACGG GGTGCGGAGG CGCACTCTGG GAATGCCGAG AGGβTCCCGC AGAβACGTCA 540
GGGCGCCβTG CGGβCCCGCG GGGAGCTGGG GGGCTAGGββ CGGACGCCGA CGTGATGGCC 600
CTTCCCGCAG GCGCCGCGGC TCTGCTACTG CTGCTGCCCG CCACCATGTT CCACCTGCTC 660
CTGGCCGCCC GTTCGβGCCC CGCGCGCCTG CTG6GTCCAC CCGCGTCCCT GCCCGGβCTG 720
GAGGTGCTGT GGAGCCCACG GGCGCTGCTG CTGTGGCTCG CCTGGCTCGG CCTGCAGβCG 780
GCGCTCTACC TACTβCCGGC GCGCAAGGTG CGGGCCCCGC TCβceβACGc TCGGGGGAGG 840
GAAGCGAATG GβCTCGβCβA GGGAAAGGAC GCCCCGGGCC TTATCAGAGC CCCCTTGGAC 900
CCGCAGTGGC CGAGGGGCAG GAATTβAAGG ACAAGAβTCG CCTGCGCTAT CCTATTAACG 960
GCTTCCAGGC CCTGGTGCTG ACAβCCCTGT TGGTGGGGCT GGGGATGTCA GCGGGGCTGC 1020
CTCTGGGGGC GCTCCCGβAA ATGCTCCTGC CCTTGGCGTT TGTCGCCACC CTCACCGCTT 1080
TCATCTTCAG CCTCTTTCTC TACATGAAGG CGCAGGTAGC CCCAGTTTCG βCCCTGGCAC 1140
CTGGGGGGAA CTCAGGCAAT CCGATTTACG ACTTTTTTCT GGGACGAGAG CTCAACCCTC 1200
GTATCTGTTT CTTCGACTTC AAATATTTCT GTGAACTGCβ ACCCGGCCTC ATCGGCTGGG 1260
TCCTCATCAA CCTGGCCCTG TTGATGAAGG AβGCAGAGCT TCGAGGCAGT CCCTCACTGG 1320
CCATCTGGCT GGTCAATGGC TTCCAGTTGC TCTACGTGGG TGATGCCCTC TGGCACGAGG 1380
AGGCCGTCCT CACCACCATG GATATCACAC ATGACGGβTT TGGCTTCATG CTGGCGTTTG 1440
GGGACATGGC CTGGGTGCCC TTCACCTACA GCCTGCAGβC CCAβTTCCTC CTGCACCACC 1500
CGCAβCCCCT GGGGTTGCCC ATGGCCTCTG TCATCTGCCT CATCAATGCT ACTGGTTACT 1560
ACATCTTCCG TGGGGCGAAT TCCCAGAAAA ACACTTTCCG AAAGAATCCT TCTGACCCCA 1620
GAGTGGCTGG GCTTGAβACC ATCTCTACAG CCACAGGGCG GAAACTGCTβ GTGTCTGGGT 1680
GGTGGGGTAT ββTCCβCCAT CCCAACTATC TTGGAGACCT CATCATGGCT CTGGCTTGGT 1740
CCTTGCCCTG CGGβGTGTCA CACCTGCTGC CCTACTTCTA CCTCCTCTAC TTCACCGCGC 1800
TGCTGCTGCA CCGTGAGGCC CGGGATGAGC GGAGTGCCTG CAGAAGTACG GCCTGGCCTG 1860
GCAGGAGTAC TGCCGGCGTG TGCCTTACCG CATCATGCCC TACATCTACT GAAβCGGCTC 1920
CACCACCCCA GGTGGGGCAT GTβCCCACTC ATCCACCAGC ACACCCAGGA CCAGGAGCCT 1980
CGACACACTT GGGACTCAAG GGCTTGGACC CCACCCAβCC CTGAGGATGA ACAACCTCAβ 2040
AβAAGAGGTG GTTTAGAGCA AGGAAAAAAA TGAAACCAGT GACCAAAAAA AAAAAAAAAA 2100
Seq ID NO: C209 DNA Sequence
Nucleic Acid Accession #: NM_015720.1
Coding sequence: 21..1838
11 21 31
CCAGTTCCGG CACGAGGACC ATGGGCCGGC TGCTGCGGGC CGCCCGGCTG CCGCCGCTGC 60
TTTCGCCGCT GCTGCTTCTG CTGGTTGGGG GAGCGTTCCT GGGTGCCTGT GTGGCTGGGT 120
CTGATGAGCC TGGCCCAGAG GGCCTCACCT CCACCTCCCT GCTAGACCTC CTGCTGCCCA 180
CTCGCTTGGA GCCACTGGAC TCAGAGGAGC CTAGTGAGAC CATGGGCCTG GGAGCTGGGC 240
TGGGAβCCCC TGGCTCAGGC TTCCCCAGCG AAGAGAAT6A AGAGTCTCGβ ATTCTGCAGC 300
CACCACAGTA CTTCTGGGAA GAGGAGGAAG AβCTCAATGA CTCAAGTCTG GACCTGGGAC 360
CCACTGCAGA TTATGTTTTT CCTGACTTAA CTGAGAAGGC AGGTTCCATT GAAGACACTA 420
GCCAGβCTCA AGAGCTGCCA AACCTCCCCT CTCCCTTβCC CAAGATGAAT CTGGTTGAGC 480
CTCCCTββCA TATGCCTCCC AGAGAββAGG AAGAAGAGGA AGAGGAAGAG GAGβAβAβGG 540
AGAAGβAAGA GGTAGAGAAA CAAGAGGAGG AGGAAGAGGA GGAGCTGGTC CCTGTGAATG 600
GATCCCAAGA AGAAGCCAAG CCTCAGβTCC GTGACTTTTC TCTCACCAGC AGCAGCCAGA 660
CCCCAGGGGC CACCAAAAGC AGGCATGAAG ACTCCGGGGA CCAGβCCTCA TCAGβTGTGG 720
AGGTGGAGAG CAGCATGGGG CCCAGCTTGC TGCTGCCTTC AβTCACCCCA ACTACAGTGA 780
CTCCGGGGGA CCAGGACTCC ACCAGCCAAG AGGCAGAGGC CACAGTGCTG CCAGCTGCAG 840
GGCTTGGGGT AGAGTTCGAG GCTCCTCAGG AAGCAAGCGA GGAAGCCACT GCAGGAGCAG 900
CTGGTTTGTC TGGCCAGCAC GAGGAGGTGC CGGCCTTGCC TTCATTCCCT CAAACCACAG 960
CTCCCAGTGG GGCCGAGCAC CCAGATGAAG ATCCCCTTGβ CTCTAGAACC TCAGCCTCTT 1020
CCCCACTGGC CCCTGGAGAC ATGGAACTGA CACCTTCCTC TGCTACCTTG GGACAAGAAG 1080
ATCTCAACCA GCAGCTCCTA GAAGGGCAGG CAGCTGAAGC TCAATCCAGG ATACCCTGGG 1140
ATTCTACGCA GGTGATCTGC AAGGACTGGA GCAATCTGGC TGGGAAAAAC TACATCATTC 1200
TGAACATGAC AGAGAACATA GACTGTβAGG TGTTCCGGCA GCACCGGGGβ CCACAGCTCC 1260
TCGCCCTGGT GGAAGAGGTG CTGCCCCGCC ATGGCAGTGG CCACCATGGG GCCTGGCACA 1320
TCTCTCTGAG CAAGCCCAGC GAGAAGGAGC AGCACCTTCT CATGACACTG GTGGGCGAGC 1380
AGGGGGTGGT GCCCACTCAA GATGTCCTTT CCATGCTGGG TGACATCCGC AGGAGGCTGG 1440
AGGAGATTGG CATCCAGAAC TATTCCACAA CCAGCAGCTG CCAGGCGCGG GCCAGCCAGG 1500
TGCGCAβCGA CTACG6CACG CTCTTCGTGβ TGCTGGTGGT CATTGGGGCC ATCTGCATCA 1560
TCATCATTGC GCTTGGCCTG CTCTACAACT GCTGGCAGCG CCGGCTGCCC AAGCTCAAGC 1620
ACGTGTCGCA CGGCGAGGAG CTGCGCTTCG TGGAGAACGG CTGCCACGAC AACCCCACGC 1680
TGGACGTGGC CAGCGACAGC CAGTCGGAGA TGCAGGAβAA GCACCCCAGC CTGAACGGCG 1740
GCGGGβCCCT CAACGGCCCG GGGAGCTGGG GGGCGCTCAT GGGGGGCAAG CGGGACCCCG 1800
AGGACTCGGA CGTGTTCGAG GAGGACACGC ACCTGTGAGC GCAGCGAGβC GCAGGCCGAG 1860
TGGGCCGCCA GGACCAAGCG AGGTCGACCC CGAAACGGAC GGCCCGGAGC CCGCACCAGC 1920
CCCGCGCCTA CCCGGCCGCC CCCGCGCCTG GCCCTCGGCG CGββCTCCTT CCCβCTTCCC 1980
CCGACTTCAC ACGGCGGCTT CGGACCAACT CCCTCACTCC CGCCCGAGGG CCAGGCCTCA 2040
AAGCCCGCCT TGGCCCCGCT TTCCCGCCCC TGAACCCCGG CCCCGCGGGC GGCGGGCGCG 2100
CTTCCTGCGC CCCGGGACTC AATTAAACCC eCCCGGAGAC CACGCGGGCC CAGCGAAAAA 2160
AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA 2220
AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAA 2269
Seq ID NO: C210 DNA Sequence
Nucleic Acid Accession #: NM_001197.3
Coding sequence : 61..543
1 11 21 31 41 51
G IACACGAAGC CITCCCββGTG GICTTACAGAC GICTGCCAGCA TICGCCGCCGC CIAGAGGAGAA 60 ATGTCTGAAG TAAGACCCCT CTCCAGAGAC ATCTTGATGG AGACCCTCCT GTATCAGCAG 120 CTCCTGGAAC CCCCGACCAT GGAGGTTCTT GGCATGACTC ACTCTGAAGA GGACCTGGAC 180
CCTATGGAGG ACTTCGATTC TTTGGAATGC ATGGAGGGCA GTGACGCATT GGCCCTCCβG 240
CTGGCCTGCA TCGGGGACGA GATGGACGTG AGCCTCAGGG CCCCGCGCCT GGCCCAGCTC 300
TCCGAGGTGG CCATGCACAG CCTGGGTCTG GCTTTCATCT ACGACCAGAC TGAβGACATC 360
AGGGATGTTC TTAGAAGTTT CATGGACββT TTCACCACAC TTAAGGAGAA CATAATGAGG 420
TTCTGGAGAT CCCCGAACCC CGGGTCCTGβ GTGTCCTGCG AACAGGTGCT GCTGGCGCTG 480
CTGCTGCTGC TGGCGCTGCT GCTGCCGCTG CTCAGCGGGG GCCTGCACCT GCTGCTCAAG 540
TGAβGCCCCG GCGβCTCAββ GCGGGGCTGG CCCCACCCCC ATGACCACTG CCCTGGAββT 600
GGCGGCCTGC TβCTβTTATC TTTTTAACTG TTTTCTCATG ATβCCTTTTT ATATTTAAAC 660
CCCGAβATAG TGCTGGAACA CTGCTGAGGT TTTATACTCA GGTTTTTTGT TTTTTTTTTA 720
TTCCAGTTTT CGTTTTTTCT AAAAGATGAA TTCCTATGGC TCTGCAATTG TCACCGGTTA 780
ACTGTGGCCT GTGCCCAGGA AGAGCCATTC ACTCCTCCCC CTGCCCACAC GGCAGGTAGC 840
AGGGββAGTG CTGβTCACAC CCCTGTGTGA TATGTGATGC CCTCGGCAAA GAATCTACTG 900
GAATAGATTC CGAGGAGCAG GAβTGCTCAA TAAAATGTTG GTTTCCAβCA AAAAAAAAAA 960
AAA 963
Seq ID NO: C211 DNA Sequence Nucleic Acid Accession ft: AF272357 Coding sequence: 83..1060
11 21 31 41 51
I I I I I
GCTGCTCCCG ACGCββAGCC CGGAGCCCGC GCCGAGCCCC TGGCCTCGCG GTGCCATGCT 60 GCCCCGGCGG CGGCGCTβAA GGATGGCGAC GCCGCTGCCT CCGCCCTCCC CGCGGCACCT 120 GCGGCTGCTβ CGβCTβCTGC TCTCCGGCCT CGTCCTCGGC GCCGCCCTGC GTGGAGCCGC 180 CβCCGGCCAC CCGβATGTAG CCGCCTGTCC CGGGAGCCTG GACTGTβCCC TβAAGAGGCG 240 GGCAAGGTGT CCTCCTGGTG CACATGCCTG TGGGCCCTGC CTTCAβCCCT TCCAGGAβGA 300 CCAGCAAGGG CTCTGTGTGC CCAGGATGCG CCGGCCTCCA ββCβGGGGCC GβCCCCAGCC 360 CAGACTGGAA GATGAGATTG ACTTCCTGGC CCAGGAGCTT GCCCGGAAGβ AGTCTGGACA 420 ATCAACTCCG CCCCTACCCA AGGACCGACA GCGGCTCCCG GAGCCTGCCA CCCTGGGCTT 480 CTCGGCACGG GGGCAGGGβC TGGAGCTGGG CCTCCCCTCC ACTCCAGGAA CCCCCACGCC 540 CACGCCCCAC ACCTCCCTGG GCTCCCCTGT GTCATCCGAC CCGGTGCACA TGTCGCCCCT 600 GβAβCCCCGG GGAGGGCAAG GCGACGGCCT CGCCCTTGTG CTGATCCTGG CGTTCTGTGT 660 GGCCGGTGCA GCCGCCCTCT CCGTAGCCTC CCTCTGCTGG TGCAGGCTGC AGCβTGAGAT 720 CCGCCTGACT CAGAAGGCCβ ACTACGCCAC TGCGAAGGCC CCTGGCTCAC CTGCAGCTCC 780 CCGGATCTCG CCTGGGGACC AGCGGCTGGC ACAGAGCGCG GAGATGTACC ACTACCAGCA 840 CCAACGGCAA CAGATGCTGT GCCTGGAGCG GCATAAAGAG CCACCCAAGG AGCTββACAC 900 GGCCTCCTCG GATGAGβAβA ATGAGGACGG AGACTTCACG GTβTACGAGT 6CCCGGGCCT 960 GGCCCCGACC ββGGAAATGG AGGTGCGCAA CCCTCTCTTC GACCACGCCG CACTGTCCGC 1020 GCCCCTGCCG GCCCCCAGCT CACCGCCTGC ACTGCCATGA CCTβGAGGCA GACAGACGCC 1080 CACCTGCTCC CCGACCTCGA GGCCCCCGGG GAGGGGCAGG GCCTGGAGCT TCCCACTAAA 1140 AACATGTTTT GATGCTGTβT GCTTTTGGCT GGGCCTCGGG CTCCAGGCCC TGGβACCCCT 1200 TGCCAGGGAG ACCCCCGAAC CTTTGTGCCA GGACACCTCC TGβTCCCCTG CACCTCTCCT 1260 GTTCGGTTTA GACCCCCAAA CTGGAGGGGG CATGGAGAAC CGTAGAGCGC AβGAACGGGT 1320 GβGTAATTCT AGAGACAAAA GCCAATTAAA GTCCATTTCA GAAAAAAAAA A 1371
Seq ID NO: C212 DNA Sequence
Nucleic Acid Accession ff: NM_004445.1
Coding sequence: 799..3819
1 11 21 31 41 51
1 1 1 1 | 1 I 1 | 1 | 1 CGGAGGGGGC GββCCββGCT GCGTTCGCTC CAGCCGCGGC TCTACAGCAG CGGGCGGCGG 60
GACCCGGGAC CCAGCTTGGC GACGGCGATT CTCGACGCGG GCCCCCAGGA TTCTCCCGGC 120
GCCCCACCTC TGGAGCAGCC CCTGCCGCCA GCGTCAGGTC CACCCCGGAA TCCCAGGGAC 180
TCTCGGCGCC GAACGGACCC GGGCCGβTGC AACGGGGTCC CCGGACTGβA GAAGACGCGG 240
GTGGCACCGT GCGAGCTCCA GGAGCCCCGG GTCCACTGCG AββCCTCGGG GGβCGCAGAC 300
CTGCAGAGAC TGCGGCCAAC GGGAAGAAAT AAAGGGATTA TAGTCCACCC AATTCACAGA 360
CTTCTGAGAC TCAGACACGA GGAGAGATAG AGAACCGCCA ATCTCTAGAT CAACAAGCAA 420
AGGAGGTGCC AAGCCTGTTT GTCTTCATTG TGACACTGGA GTCTAGATβC TGGGAAGTCC 480
AAGATCAGGG TGCCββCATG GTCAGTTCCT GGCGAAGCCT CTCTTCTAGG TTTCAGACTG 540
CCCTCTTCTT TGTTGTGTCC TCGAATGGCA GAAAAAGGGG TGβCTGTTGG AGGAAβββAG 600
GAβAGTAAAT GAAGAGAAAG AACTGGAATA ACCCCTTGCA GAAAAAAAAA AAAAGGGAAG 660
CTTAGCTGTA CACCCTGAGT CTTGCAAAAG CTGCAGCCCC ACCCAGGAGC AGβGTGGTGG 720
CTGGGGCGAT GGTGGACGCC CTGAAGATGT CCCATGGCTA CTGAAGGGβC TGCCCAGTTA 780
GGGAACAGAG TGGCGGGCAT GGTGTGTAGC CTATGGβTCC TGCTCCTGGT GTCTTCAGTT 840
CTGGCTCTGG AAGAGGTATT GCTGGACACC ACCGGAGAβA CATCTβAβAT TGGCTGGCTC 900
ACCTACCCAC CAGGGGGGTG GGACGAGGTβ AGTGTTCTGG ACGACCAGCG ACGCCTGACT 960
CGGACCTTTG AGβCATGTCA TGTGGCAGGG GCCCCTCCAG GCACCGGGCA GGACAATTCG 1020
TTGCAGACAC ACTTTGTGGA GCGGCGCGGG GCCCAβAGGG CGCACATTCG ACTCCACTTC 1080
TCTGTGCGGG CATGCTCCAβ CCTGβGTGTG AGCGGCGGCA CCTGCCGGGA GACCTTCACC 1140
CTTTACTACC GTCAGGCTGA GβAGCCCGAC AGCCCTGACA GCGTTTCCTC CTGGCACCTC 1200
AAACGCTGGA CCAAGGTGGA CACAATTGCA GCAGACGAGA GCTTTCCCTC CTCCTCCTCC 1260
TCCTCCTCCT CTTCTTCCTC TβCAβCβTGG GCTβTGGβAC CCCACGGGGC TGGGCAGCGG 1320
GCTGGACTGC AACTGAACGT CAAAGAGCGG AGCTTTGGGC CTCTCACCCA ACGCGGCTTC 1380
TACGTGGCCT TCCAGGACAC GGGG6CCTGC CTCGCCCTGG TCGCTβTCAG GCTCTTCTCC 1440
TACACCTGCC CTGCCGTGCT CCGATCCTTT GCTTCCTTTC CAGAGACGCA GGCCAGTGGG 1500
GCTGβGGGGG CCTCCCTGGT GGCAGCTGTG GGCACCTGTG TGGCTCATGC AGAGCCAGAG 1560
GAβGATGGAG TAGGGGGCCA GGCAGGAGGC AGCCCCCCCA GGCTGCACTG CAACGGGGAG 1620
GGCAAGTGGA TGGTAGCTGT CGGGGGCTGC CGCTGCCAGC CTGGATACCA ACCAGGACGA 1680
GGAGACAAGβ CCTGCCAAGC CTGCCCACGG GGGCTCTATA AGTCTTCTGC TGGGAATGCT 1740
CCCTGCTCAC CATβCCCTβC CCGCAGTCAC GCTCCCAACC CAGCAGCCCC CGTTTGCCCC 1800
TGCCTGGAGG GCTTCTACCG GGCCAGTTCC GACCCACCAG AGGCCCCCTG CACTGCTCCT 1860
CCATCGGCTC CCCAGGAGCT TTβGTTTGAG GTGCAAGβCT CAGCACTCAT GCTACACTGG 1920 CGCCTGCCTC GβGAGCTGGG GGGTCGAGGG GACCTβCTCT TCAATGTCGT GTGCAAGGAG 1980
TGTGAAGGCC GCCAGGAACC TGCCAGCGGT ββTGGβGGCA CTTGTCACCG CTGCAGGGAT 2040
GAβGTCCACT TCGACCCTCG CCAGAGAGGC CTGACTGAGA GCCGAGTGTT AGTGGGGGGA 2100
CTCCGGGCAC ACGTACCCTA CATCTTAGAG GTGCAGGCTG TTAATβGGGT GTCTGAGCTC 2160
5 AGCCCTGACC CTCCTCAGGC TGCAGCCATC AATGTCAGCA CCAGCCATβA AGTGCCCTCT 2220
GCTGTCCCTG TGGTGCACCA GGTGAGCCGG GCATCCAACA GCATCACCGT GTCCTGGCCG 2280
CAGCCCGACC AGACCAATGG GAACATCCTG GACTATCAGC TCCGCTACTA TGACCAGGCA 2340 βAAβACGAAT CCCACTCCTT CACCCTGACC ACCGAGACCA ACACTGCCAC CGTGACACAG 2400
CTGAGCCCTG GCCACATCTA TGGTTTCCAG GTGCGGGCCC GβACTβCTGC CGGCCACGGC 2460 0 CCCTACGGGG GCAAAGTCTA TTTCCAGACA CTTCCTCAAG GGGAGCTGTC TTCCCAGCTT 2520
CCGβAAAGAC TCTCCTTGGT GATCGGCTCC ATCCTGβGGβ CTTTGGCCTT CCTCCTGCTG 2580
GCAGCCATCA CCGTGCTGGC GGTCGTCTTC CAGCGGAAGC GGCGTGGGAC TGGCTACACG 2640
GAβCAβCTGC AGCAATACAG CAGCCCAGGA CTCGGGGTGA AGTATTACAT CGACCCCTCC 2700
ACCTACGAGβ ACCCCTGTCA GGCCATCCGA GAACTTGCCC GGGAAGTCGA TCCTGCTTAT 2760 5 ATCAAGATTG AGGAGGTCAT TGGGACAGGC TCTTTTGGAG AAβTβCGCCA GGGCCGCCTG 2820
CAGCCACGGG GACGGAGGGA GCAGACTGTG GCCATCCAGG CCCTGTGGGC CGGGGGCGCC 2880
GAAAGCCTβC AGATGACCTT CCTGGGCCGβ GCCGCAGTGC TGGGTCAGTT CCAGCACCCC 2940
AACATCCTGC GβCTGGAGGG CGTGGTCACC AAGAGCCGAC CCCTCATGGT GCTGACGGAG 3000
TTCATGGAGC TTGGCCCCCT GGACAGCTTC CTCAGGCAGC GGGAGGGCCA GTTCAGCAGC 3060 0 CTGCAGCTGG TGGCCATGCA βCGGGGAGTG GCTGCTGCCA TGCAGTACCT GTCCAGCTTT 3120
GCCTTCGTCC ATCGCTCGCT GTCTGCCCAC AGCGTGCTGG TGAATAβCCA CTTGGTGTGC 3180
AAGGTGGCCC CTCTTGGCCA CAGTCCTCAG GGCCCAAGTT GTTTGCTTCG CTGGGCAGCC 3240
CCAGAGGTCA TTGCACATGG AAAGCATACA ACATCCAGTG ATGTCTGGAG CTTTGGGATA 3300
CTCATGTGGG AAGTGATGAG TTATGGAGAA CGGCCTTACT GGGACATGAG TGAGCAGGAG 3360 5 GTACTAAATG CAATAGAGCA GGAGTTCCGG CTGCCCCCGC CTCCAGGCTG TCCTCCTGGA 3420
TTACATCTAC TTATGTTGGA CACTTGGCAG AAGβACCGTG CCCGGCββCC TCATTTTGAC 3480
CAGCTGGTGG CTGCATTTGA CAAGATGATC CGCAAGCCAG ATACCCTGCA GGCTGGCGGG 3540
GACCCAGGGG AAAGGCCTTC CCAGGCCCTT CTGACCCCTG TGGCCCTGGA CTTTCCTTGT 3600
CTGGACTCAC CCCAβGCCTG GCTTTCAGCC ATTGGACTGG AGTGCTACCA GGACAACTTC 3660 0 TCCAAGTTTG βCCTCTGTAC CTTCAGTGAT GTGGCTCAGC TCAGCCTAGA AGACCTGCCT 3720 βCCCTβGGCA TCACCCTGGC TGGCCACCAG AAGAAGCTβC TGCACCACAT CCAGCTCCTT 3780
CAGCAACACC TGAGGCAGCA GGβCTCAGTG GAGβTCTβAG AATGACGATA CCCGTGACTC 3840
AGCCCTGGAC ACTGGTCCGA GAAGGGACAT GTGGGACGTG AGCCGGGCTC CAACAGCCTC 3900
TGTGAGAGAT GCCCCACACC AAACCCAACC CTCCCGATβG CTGCATTCCC TGGTCCTCCG 3960 5 CCTCTCCACC AGCCCCCTCC TCATTAAAGG GAAAGAAGGG AATTTGCAAA 4010
Seq ID NO: C213 DNA Sequence
Nucleic Acid Accession ft: XM_043340.4
Coding sequence: 195..1067 0
1 11 21 31 41 51
I I I I I I
GGGCGGCGCC CAATGGGCTG CGCGGAGCGT CACTTCCCGG CAGCGGGAGG CGAGTGGCGA 60
GTCβCGAGTG GCGAGTGTCA GGGGGGCGGC CGGCGGGGGC ββGGCGβCCG GAGGAGGCGT 120 5 TGGCAGCGGG CTCGGACCCA CGCGGCβCCG CGGCCCGCCT GGCCTGCAGC GCTCCCACCC 180
CCGGCGGCGG CACGATGCCC TTTGACTTCA GGAGGTTTβA CATCTACAGG AAGGTGCCCA 240
AGGACCTTAC GCAGCCAACG TACACCGGGG CCATTATCTC CATCTGCTGC TGCCTCTTCA 300
TCCTCTTCCT CTTCCTCTCG GAβCTCACCG GATTTATAAC GACAGAAβTT βTGAACGAGC 360
TCTATGTCCA TCACCCAβAC AAGGACAGCG GTGGCAAGAT CGACGTCAGT CTGAACATCA 420 0 GTTTACCCAA TCTβCACTGC GAGTTGGTTG GGCTTGACAT TCAGGATGAG ATGGGCAGGC 480
ACGAAβTGGG CCACATCGAC AACTCCATGA AGATCCCGCT GAACAATGGG GCAGGCTGCC 540
GCTTCGAGGβ GCAGTTCAGC ATCAACAAGG TCCCCGGCAA CTTCCACGTG TGCACACACA 600
GTGCCACAGC CCAGCCACAG AACCCAGACA TGACGCATGT CATCCAGAAG CTCTCCTTTG 660 βββACACGCT ACAGGTCCAG AACATCCACG GAGCTTTCAA TGCTCTCGGG GGAGCAGACA 720 5 GACTCACCTC CAACCCCCTG GCCTCCCACG ACTACATCCT GAAGATTGTG CCCACGGTTT 780
ATGAGGACAA GAGTGβCAAG CAGCGGTACT CCTACCAGTA CACGGTGGCC AACAAGGAAT 840
ACGTCGCCTA CAGCCACACG GGCCGCATCA TCCCTGCAAT CTGGTTCCGC TACGACCTCA 900
GCCCCATCAC GGTCAAGTAC ACAGAGAGAC GGCAGCCGCT GTACAGATTC ATCACCACGA 960
TCTGTGCCAT CATTGβCGGG ACCTTCACCG TCGCCGGCAT CCTGGACTCA TGCATCTTCA 1020 0 CAGCCTCTGA GGCCTGGAAG AAGATCCAGC TGGGCAAβAT GCATTGAC6C CACACCCAGC 1080
CTAATGGCCG AGGACCCTGG GCATCGCCAG CCTTGCCTCC AGTGCCCTGT CTCCTTTGGC 1140
CCTCAATCTG GTCCCAAATC TGGCTCTCTC CCAAAGGGTG TGTβGGAAGT GGGGGGAAAG 1200
TAGAGGATGG CTCGATGTTT TGCAGCTACC TCTTTTCCCC GTβTTTCTTT TTAGACAAAT 1260
TACACTGCCT GAAGTTGCAG TTCCCCTTTC CCTGGGGAGC CCCAAGAACA GAGTCAGGCA 1320 5 AGGGβTCGGG AGTCCAGGGG AACATCCCAG AATGCATATC GATCAGCTCT CAGCCAGGCT 1380
TCGACAATCT CGCAGCCCCC ACTAGGTβGA CACATTAATG ATTTGGTTTC TCCCCTGGGC 1440
AGCCAACCTG CCCCAGAGGC ACCAGACCTG GGCTTTCAGC TTTGGGACCA GGCTGCCCAA 1500
AG6TACTCCT TTATACACCC GGCACCTTCC ACGAAAGATβ GTACTTCCCA AGCAAGCCCC 1560
TATGATTTGT CACTATAGAT GGAAATGTGT GGCATGCACA TGAGTTGAAA TTCTTTTATG 1620 0 CATTTTTTTG AAGAAAAAAA AAAAAACAAC TCTGAGGACA TAGGGGATβT CAGTTTCCTA 1680
TGGAAGAGAC ACCTCTGACC CGTTATTCTT ATAATCAAAA TCTGAAGG6A AAAAAATGTT 1740
TTAGTTCTTT CCCCACTCGT TGGGTTCAAC TAGATTAAAA GGCTGATTTT CAG 1793
Seq ID NO : C214 DNA Sequence I D Nucleic Acid Accession # : NM_002151 .
Coding sequence : 246 . .1499
1 11 21 31 41 51
I I I I I I
80 TCGAGCCCGC TTTCCAGGGA CCCTACCTGA GGGCCCACAG GTβAGGCAGC CTGGCCTAGC 60
ACβCCCCACG CCACCGCCTC TGCCTCCAGG CCGCCCGCTG CTβCGGGGCC ACCATGCTCC 120
TGCCCAGGCC TGGAGACTGA CCCGACCCCG GCACTACCTC GAGGCTCCGC CCCCACCTGC 180
TGGACCCCAG GGTCCCACCC TGGCCCAGGA GGTCAGCCAG GGAATCATTA ACAAGAGGCA 240
GTGACATGGC GCAGAAGGAG GGTGGCCGGA CTGTGCCATβ CTGCTCCAGA CCCAAGβTGG 300 CAβCTCTCAC TGCGGGGACC CTGCTACTTC TGACAGCCAT CGGGGCGGCA TCCTGGGCCA 360
TTGTGGCTGT TCTCCTCAGG AGTGACCAGG AGCCGCTGTA CCCAGTGCAG GTCAGCTCTG 420
CGGACGCTCG GCTCATGGTC TTTGACAAGA CGGAAGGGAC βTGGCGGCTG CTGTβCTCCT 480
CCCCCTCCAA CGCCACGGTA GCCGGACTCA GCTGCGAGGA GATGGGCTTC CTCAβGGCAC 540
TCACCCACTC CGAGCTGGAC GTGCGAACGG CGGGCGCCAA TGGCACGTCG GβCTTCTTCT 600
GTCTGGACGA GGGGAGβCTG CCCCACACCC AGAGβCTGCT GGAGGTCATC TCCGTGTGTG 660
ATTGCCCCAG AGGCCGTTTC TTGGCCGCCA TCTGCCAAGA CTGTGGCCGC AGGAAGCTGC 720
CCGTGGACCG CATCGTGGGA GGCCGGGACA CCAGCTTGGG CCGβTGGCCG TGGCAAGTCA 780
GCCTTCGCTA TGATGGAGCA CACCTCTGTβ GGGGATCCCT GCTCTCCGGG GACTGGGTGC 840
TGACAGCCGC CCACTGCTTC CCGGAGCββA ACCGGGTCCT GTCCCGATGG CGAGTGTTTG 900
CCGGTGCCGT GGCCCAGGCC TCTCCCCACβ GTCTGCAGCT GGGGGTGCAG GCTGTGGTCT 960
ACCACGGGGG CTATCTTCCC TTTCGGGACC CCAACAGCGA GGAGAACAGC AACGATATTG 1020
CCCTGGTCCA CCTCTCCAGT CCCCTGCCCC TCACAGAATA CATCCAGCCT GTGTGCCTCC 1080
CAGCTGCCGG CCAGGCCCTG GTGGATGGCA AGATCTGTAC CGTGACGGGC TGGGGCAACA 1140
CGCAGTACTA TββCCAACAG GCCGGGGTAC TCCAGGAGGC TCGAGTCCCC ATAATCAGCA 1200
ATGATGTCTG CAATGGCGCT GACTTCTATG GAAACCAGAT CAAGCCCAAG ATGTTCTGTG 1260
CTGGCTACCC CGAGGGTGGC ATTGATGCCT GCCAGGGCGA CAGCGGTGGT CCCTTTGTGT 1320
GTGAGGACAG CATCTCTCGG ACGCCACGTT GGCGGCTGTG TGβCATTGTG AGTTCGGGCA 1380
CTGGCTGTGC CCTGGCCCAG AAGCCAGGCG TCTACACCAA AGTCACTGAC TTCCGGGAGT 1440
GGATCTTCCA GGCCATAAAG ACTCACTCCG AAGCCAGCGG CATGGTGACC CAGCTCTGAC 1500
CGGTGGCTTC TCGCTGCGCA GCCTCCAGGG CCCGAGGTGA TCCCGGTGGT GGGATCCACG 1560
CTGGGCCGAG GATGGGACCT TTTTCTTCTT GGGCCCGGTC CACAGGTCCA AGβACACCCT 1620
CCCTCCAGGG TCCTCTCTTC CACAGTGGCG GGCCCACTCA GCCCCGAGAC CACCCAACCT 1680
CACCCTCCTG ACCCCCATGT AAATATTGTT CTGCTGTCTG GGACTCCTGT CTAGGTGCCC 1740
CTGATGATGG GATGCTCTTT AAATAATAAA GATGGTTTTG ATT 1783
Seq ID NO: C215 DNA Sequence Nucleic Acid Accession #: AB037745.1 Coding sequence: 26..1744
1 11 21 31 41 51
A ITGGTGGAAC AICGCTGCCCA CIAAACATGGA AIACGACCGTT CITCAGTGGGA TICAACTTCGA 60
GTACAAGGGC ATGACAGGCT GGGAGGTGGC TGGTGATCAC ATTTACACAβ CTGCTGGAGC 120
CTCAGACAAT GACTTCATGA TTCTCACTCT GGTTGTGCCA GGATTTAGAC CTCCGCAGTC 180
GβTGATGGCA GACACAGAGA ATAAAGAGGT GGCCAGAATC ACATTTGTCT TTGAGACCCT 240
CTGTTCT6TG AACTGTGAGC TCTACTTCAT GGTGGGTGTG AATTCTAGGA CCAACACTCC 300
TGTGGAGACG TGGAAAGGTT CCAAAGGCAA ACAGTCCTAT ACCTACATCA TTGAGGAGAA 360
CACTACCACG AGCTTCACCT GGGCCTTCCA GAGGACCACT TTTCATGAGG CAAGCAGGAA 420
GTACACCAAT GACGTTGCCA AGATCTACTC CATCAATGTC ACCAATGTTA TGAATGGCGT 480 ββCCTCCTAC TGCCGTCCCT GTGCCCTAGA AGCCTCTGAT GTGGGCTCCT CCTGCACCTC 540
TTGTCCTGCT GGTTACTATA TTGACCGAGA TTCAGGAACC TGCCACTCCT GCCCCCCTAA 600
CACAATTCTG AAAGCCCACC AGCCTTATGG TGTCCAGGCC TGTGTGCCCT GTGGTCCAGG 660
GACCAAGAAC AACAAGATCC ACTCTCTGTG CTACAATGAT TGCACCTTCT CACGCAACAC 720
TCCAACCAGG ACTTTCAACT ACAACTTCTC CGCTTTGGCA AACACCGTCA CTCTTGCTGG 780
AGGGCCAAGC TTCACTTCCA AAGGGTTGAA ATACTTCCAT CACTTTACCC TCAGTCTCTG 840
TGGAAACCAG GGTAGGAAAA TGTCTGTGTG CACCGACAAT GTCACTGACC TCCGGATTCC 900
TβAGGGTGAG TCAGβGTTCT CCAAATCTAT CACAGCCTAC GTCTGCCAGG CAGTCATCAT 960
CCCCCCAGAβ GTGACAGGCT ACAAGGCCGG GGTTTCCTCA CAGCCTGTCA GCCTTGCTGA 1020
TCGACTTATT GGGGTGACAA CAGATATGAC TCTGGATGGA ATCACCTCCC CAGCTGAACT 1080
TTTCCACCTG GAGTCCTTGG GAATACCGGA CGTGATCTTC TTTTATAGβT CCAATGATGT 1140
GACCCAGTCC TGCAGTTCTG GGAGATCAAC CACCATCCGC GTCAGGTGCA GTCCACAβAA 1200
AACTGTCCCT GβAAGTTTGC TGCTGCCAGG AACGTGCTCA GATGGGACCT GTGATGGCTG 1260
CAACTTCCAC TTCCTGTGGG AGAGCGCGGC TGCTTGCCCG CTCTGCTCAG TGβCTGACTA 1320
CCATGCTATC GTCAGCAGCT GTGTGGCTGG GATCCAGAAG ACTACTTACG TGTGGCGAGA 1380
ACCCAAGCTA TGCTCTGGTG GCATTTCTCT GCCTGAGCAG AGAGTCACCA TCTGCAAAAC 1440
CATAGATTTC TGGCTGAAAG TGGGCATCTC TGCAGGCACC TGTACTGCCA TCCTGCTCAC 1500
CGTCTTGACC TGCTACTTTT GGAAAAAGAA TCAAAAACTA GAGTACAAGT ACTCCAAGCT 1560
GGTGATGAAT GCTACTCTCA AGGACTGTGA CCTGCCAGCA GCTGACAGCT GCGCCATCAT 1620
GGAAGGCGAG GATGTAGAGG ACGACCTCAT CTTTACCAGC AAGAAGTCAC TCTTT6GGAA 1680
GATCAAATCA TTTACCTCCA AGCAGCCAGC TCCTGTCACC ATCTCTCTTT CAGAGGACTC 1740
CTGATGGATT TGACTCAGTG CCGCTGAAβA CATCCTCAGG AGGCCCAGAC ATGGACCTGT 1800
GAGAGGCACT GCCTGCCTCA CCTGCCTCCT CACCTTGCAT AGCACCTTTG CAAGCCTGCG 1860 βCGATTTGGG TGCCAGCATC CTGCAACACC CACTGCTGGA AATCTCTTCA TTGTGGCCTT 1920
ATCAGATGTT TGAATTTCAG ATCTTTTTTT ATAGAGTACC CAAACCCTCC TTTCTGCTTG 1980
CCTCAAACCT GCCAAATATA CCCACACTTT GTTTGTAAAT TATGCCCTTG CTTGTATCTT 2040
GTTTCCCAAA ATGGCCCATC CGCCAGAGCC ATAGCTTCGT CTGCTCATAA TTCTTATAGC 2100
TTTGGAATGA AAATATTTCT ATCTTCTTAA GTATAGAAAC TATTTCCTCT GTCCTCTAAC 2160
TTAAGGGCAG AAACAGCTCG GAGTTTTCCT CGCATGCCCT CAGCTCATGA TCTCTTCAGG 2220
AGA6AGGCTG GGTGAGGAGG GTGTCGGGGT TCCCTGGTGG ATAATCTTCA TAGCAGCCTG 2280
GATCCATTTC CCCTGGATAA CCAGCTCAAA GGGA6TGAAA ATGGTAGTCT GAGGGCAAGβ 2340
GGAGCAAGGC CTGGGTAAGA AAAGCCTTGA AAAGCATAAA AAGAGGCCβG GCGCGGTGGC 2400
TCACGCCTGT AATCCCAGCA CTTTGGGAGG CCGAβGCGGG CAGATCATGA GGTCGGGAGA 2460
TTGAGACCAT CCTGβCTAAC ACGGTGAAGC CCCGTCTCTA CTGGAAATAC AAAAAATTAG 2520
CCGGGCGTGG TGGCGGGTGC CTGTGGTCCC AGCTACTCGG GAGGCTGAGG CGGGAGAATA 2580
GCGTGGGCCT GβAAGGCGGA GCTTGCAGTG AGCCGAGATC GCGCCACTGC ACTCCATCCA 2640
GCCTGGGTGA CAGAGTGAGA CTCTGCCTCA AAAAAAAAAA AAAAAAAGAA AAGCACAAAG 2700
AGAβGCAACA AGGAATGTTT TTGTTTTTGA GACAGGCTCT CACTCTGTCA CCTAGGCTGG 2760
AGTβCACTGG CGTAATCACT GTTCAGTGCA GCCTCAAGCT CTTGGGCTCA G6CTATCCTC 2820
CCATCTCACC CTCTCAAGTA GCTGGGACTA CGAGTGTGCA CCACCAGGCT CACTAATTTT 2880
TGTGTTTTTT GTAGACACGG GGTTTCACCG TGTTGCCCAG GCTGGTCTCC AACTCCTGGG 2940
CTCAAGTGAT CTGTCCGCCT CGGCCTCCCA AACTGCTGGG ATTACAGGCA TAAGCCACTG 3000
CACTCAGCCT TTTATTTGTT TTTTAAACCA CGTAGCTCAT TGCCTTCTCT TAAGTAAATG 3060
ATACATATTC TCACTGAAGC CAAAGGAATA AGTTCATCAA GAAAATGCCC AAAGCCCTGG 3120 TβGATACATC CTCCCTATCT TTTTTTTAAA CCTTCCACTA TCACTCTATG ACACTGAAAA 3180
GAACCAGGTA AGCCCCAAAC CCAGATGTTC CAGCCTTATC CTCTATTGGG TTTACCCACA 3240
GACATAGCAA ACCCTGTCAG TGAGGAAAAT TCCCCATCCT TGAGTCCCCC CGTCCTAGAA 3300
GTTTGGGCCA TATTATGGAA CAGββGTCTC TTATTTGAAA AGAGCACAAβ GAGGCCAAGA 3360
TTTTAATGGG GCACTTTAGG GGATACAGCC CACAATGGCA TGGGCCTGAG GTGGCCGTGA 3420
TGTCTGCTTC TAAGCTTAAC GCATCTGCTC AGGCACAGAA TAAACGTCTA GGCTGGCCAA 3480
AAAAGGAACT GAATCCCAGG CCCATACGCC AGCACCAGAA TCAAACCAGT CTTCAAGGAA 3540
GGAAGGCTAG GAGAGTTTAA CAAGATTTTC ACTGGGCCCA GCATGGTGGC TCACACCTGT 3600
AATCCCAAGG CAGAATGGTG GCTTGAGCTC AGGAGTTCAA GACCAGCCTG GβCAACACAβ 3660
TGAGACCCTG TCTCTAAAAA ATTTAAAAAT AAACAAGGTG TTCACCAACC TC6GATACTT 3720
CTCACTATTA AGCCCCTATC TTTCTCTTTT TTTCATTCTC AATTCCTTTG TGTGATAAAA 3780
AACTAAAGAG ACTTCTGGTC CAATTTCTGG CAACATCCCT TCTGAAAGGT GAGTAGAGTG 3840
GGTGTCTTCT ATCCCCATTT TCCCCAATTT TACACAAACT ATTATCAATG AACTTTTAAG 3900
TACCTAGAAT GGGTAAAACC AGAGCAAGAC TTTAAATTAC CTTCTTCTTT CTTCTACTGG 3960
CAGTTCTGCC TCCATCACTA TCAGGCTAGG GTGACCTTCC CTTGGTCAAG CCCCAATTGC 4020
CCATGATTTG TGCCTGTGCC CTTTCTCCAG TGACCATTTG GTGACCAGAT GGTAGATATA 4080
GAAAGGGGAT GGCATTTGCA AGTGACTAGT CTGCCACAAA ATGCTCATCT GATTAGCCAC 4140
TGCTGCCCTG GCAATGGCTT TGTAAGAGTC AATGAGAACT AGA6CCAGGC TGTGGTCCCT 4200
GGCCATCAAC AGTβTTGGTG ACGGCAGGGA GTCCCTTTGβ TTTAATAAAT CCAGTTTTTC 4260
TTTGGGTATC CAAATTCTCC CCTCCTTTTG TAGGAGTCAG GCTCTCAGAA CCTGTGTCCA 4320
TGTTGGAACT TCCCCCAGTG TG6ATCCAGA TACGCAGCTC CTGAGCTCCA GCCTAAAGTC 4380
TTCTGTAGCC TCAGCAATAC TTCGβCACCT GCTGTCTCAC TGAATAGCTT TCTTTTGTGA 4440
CAAAGGCCAC AGACAGCCCT TAGACTATTC CGGAAACAGT AGGAAAAATT ACATATGTCT 4500
TTGACTTCTT TATTCTGACT CCACTGATTT TAGCCATAAT ACTTTAAGGA GCTACTTTTT 4560
ACTACCCCTT ACCGTCCTGA CTTCTGCAGG TCTGCCCTGT GACCTGTCAG GAACTCCTGA 4620
GTTACGCTAC TGGGGTCACC TGTTGCTCCC CTAGCAAGTT AGGCATGTCA TATATTTTTA 4680
ACAGCTTTAT TGAGATATAA TTCACATATT ATACAATTCA CCTTTAAAAC ATACGATTCA 4740
ATGGTTTTCA GCAAACTCAC AGAβTTβTCC GCCCACTTGA GAGCAAACAC ATGTTCAATT 4800
TTCTTTTCCT TTTTTTTTTT GAGACAGAGT CAGCTTTβTC GCCCAGGCTG GAGTGCAGTβ 4860
CCATGATCTT GGCTCACTGC AGCCTCCCCA TCCTGGGTTC AAGTβATCCT TCTGCTTCAG 4920
CCTCCCCAGT AGCTGGGATT ACAGGCATGC GCCACCACGC CTAGCTAATT TTTGTGTTTT 4980
TAGTAGAGAT GGGGTTTCAC CGTGTTGGCC AGGCTGGTCT CAAACTCCTG GACTCAAGTG 5040
ATCCACCCAC CTCGGCCTCC CAAAGTGCTG GGATTGCAGG TGTGAGCCAC CGTβCCTGGC 5100
CTACGTGTTC AATTTTCTAT GAACAAAGGC TTTAGTCCTT GACCCAGGGC TAAAGTββTC 5160
TGTCCAAGCT GTTGTTGGTA GAGβGAGTAT GATAAAATGT TTAAATCTCA TTTGGTTACC 5220
TTGAGTCCTG GAACACGCAG TAACTGTCAT GCTATAβTCA TCATCTGTAT TTGGCTCGGA 5280
ATACAAATGA AGATTGTGGT GTATTCAAGC AβTAGGGTTT TTGCTTTTGT TTTTGTTTTA 5340
GTGCCAACAA AACTTTTTTT TGTCTβACTA CATTAAAGAT AAGACTGACT ATATTTATAC 5400
AACAGAAACT TTGTAATAGA TTTTTTCAGC TTTCTCAAAT CGAATTTTTT TTCATCAβGG 5460
CTGGTTGGAT TTCCTTTTTA CCCTGTAATC CAAGCGTTAA TAGTTTGTTA GAAGATGββT 5520
TATTCCATGT CACTTTTTTT TTTTTβTAAA ATAAAAACAT ACCTTAC 5567
Seq ID NO: C216 DNA Sequence
Nucleic Acid Accession ft : NM_004864.1
Coding sequence: 26-952
1 11 21 31 41 51
1 1 | 1 | 1 | 1 J 1 | 1 CGGAACGAGG GCAACCTGCA CAGCCATGCC CGGGCAAGAA CTCAGβACGG TGAATGGCTC 60
TCAGATGCTC CTGGTGTTGC TGGTGCTCTC GTGGCTGCCG CATGGGGGCG CCCTGTCTCT 120
GGCCGAGGCG AGCCGCGCAA 6TTTCCCGGG ACCCTCAGAG TTGCACTCCG AAGACTCCAG 180
ATTCCGAGAG TTGCGGAAAC GCTACGAββA CCTGCTAACC AGGCTGCGGG CCAACCAGAG 240
CTGGGAAGAT TCGAACACCG ACCTCGTCCC GGCCCCTGCA GTCCGGATAC TCACGCCAGA 300
AGTGCGGCTG GβATCCGGCG GCCACCTGCA CCTGCβTATC TCTCGGGCCG CCCTTCCCGA 360
GGGGCTCCCC GAGGCCTCCC GCCTTCACCG GGCTCTGTTC CGGCTGTCCC CGACGβCGTC 420
AAGGTCGTGG GACGTGACAC GACCGCTGCG GCGTCAGCTC AGCCTTGCAA GACCCCAAGC 480
GCCCGCGCTG CACCTGCGAC TGTCGCCGCC GCCGTCβCAG TCGGACCAAC TGCTGGCAGA 540
ATCTTCGTCC GCACGGCCCC AGCTGGAGTT GCACTTGCGG CCGCAAGCCG CCAGββββCβ 600
CCGCAGAGCG CGTGCGCGCA ACGGGGACGA CTGTCCGCTC GGGCCCGGGC GTTGCTGCCβ 660
TCTGCACACG GTCCGCGCGT CGCTGGAAβA CCTGGGCTGG GCCβATTGGβ TGCTGTCGCC 720
ACGGGAGGTG CAAGTGACCA TGTGCATCGG CGCGTGCCCG AGCCAGTTCC GβGCGGCAAA 780
CATGCACGCG CAGATCAAGA CGAβCCTGCA CCGCCTGAAG CCCGACACGG AGCCAGCGCC 840
CTGCTGCGTG CCCGCCAGCT ACAATCCCAT GGTGCTCATT CAAAAGACCG ACACCGββGT 900
GTCGCTCCAG ACCTATGATG ACTTGTTAGC CAAAGACTGC CACTGCATAT GAGCAGTCCT 960
GGTCCTTCCA CTGTCCACCT GCGCGGG∞A GGCGACCTCA GTTβTCCTGC CCTGTGGAAT 1020
GGGCTCAAGG TTCCTGAGAC ACCCGATTCC TGCCCAAACA GCTGTATTTA TATAAGTCTG 1080
TTATTTATTA TTAATTTATT GGGGTGACCT TCTTGGGGAC TCGGGGGCTG GTCTGATGGA 1140
ACTGTGTATT TATTTAAAAC TCTGGTGATA AAAATAAAGC TGTCTGAACT GTTAAAAAAA 1200
AAAA 1204
Seq ID NO: C432 DNA Sequence
Nucleic Acid Accession #: NM_052858.1
Coding sequence: 54..1259
11 21 31 41 51
I I I I I
GGCACGAGGT GTTGCCCTCA GGTCGCTCCC GGGCGCGGAC ACGGAACCCG GCCATGGAAG 60 ATCCGTCGβG GGCTCGCGAG CCCCGGGCCC GGCCGAGAGA GCGGGACCCG GβACGGCGCC 120 CCCACCCAGA CCAAGGCCGC ACCCACGATC GACCGCGGGA CCGACCCGGG GACCCGCGCA 180 GGAAGCGAAG CAGCGACGGG AACCGGCGAA GG6ACGGGGA CCGGGACCCG AAGAGAβACC 240 AGGAGAGGGA CGGGAACCGC GACCGGAACC GGGACCGGGA GAGGGAGAGA CAGAGGGAAA 300 GAGACCCGGA CCGAGGCCCC CGCCGGGACA CACACAGGGA CβCGGGCCCT CGCGCAGGTG 360 AACACGβAβT TTGGGAAAAA CCGCGCCAAA GCCGGACGCG GGACGGAGCC CGGGGACTGA 420 CCTGGGACGC AGCCGCGCCT CCTGGGCCCG CGCCCTGGGA AGCCCCGGAG CCGCCGCAGC 480 CGCAGAGGAA GGGAGACCCC GGGCGCCGCA GACCCGAAAG TGAACCCCCT TCGGAGAGAT 540
ATCTCCCCTC GACCCCCAGG CCTGGACGAG AGGAGGTGGA ATATTACCAG TCAβAββCGG 600
AAGGACTCCT GGAATGCCAC AAATGCAAAT ACTTGTGCAC TGGGAGAGCC TGCTGCCAAA 660
TGCTGGAββT TCTCCTGAAC TTGCTGATCC TGGCCTGCAG CTCTGTGTCT TACAGTTCCA 720
CAGGβGGCTA CACGGGCATC ACCAGCTTGG GGGGCATTTA CTACTATCAG TTCGGAGGGG 780
CTTACAGTGG CTTTGATGGT GCTGACGβGG AGAAGGCCCA GCAACTβGAT GTCCAGTTCT 840
ACCAGCTAAA GCTGCCCATG GTCACTGTGG CAATGGCCTG TAGTββAβCC CTCACAGCCC 900
TCTGCTGCCT CTTCGTTGCC ATGGGTβTCC TGCGβGTCCC GTββCATTGT CCACTGTTGC 960
TGGTGACCGA AGGCTTCTTG GACATGCTCA TCGCGGGGGG GTACATCCCG GCCTTGTACT 1020
10 TCTACTTCCA CTACCTCTCT GCTGCCTATG GCTCTCCTGT GTGTAAAβAβ AGGCAGGCGC 1080
TGTACCAAAG CAAAGGCTAC AGCGGTTTCG GCTGCAGTTT CCACGGAβCA GATATAGGAG 1140
CTGGAATCTT TGCTGCCCTG GGCATTGTGG TCTTTGCCCT GGGGGCGGTC CTGGCCATAA 1200
AGGGCTACCG AAAAGTTAGG AAGCTAAAAG AGAAβCCAβC AGAAATGTTT GAATTTTAAG 1260
GGTTTCTAAA ACGCTCTGAC AGATGCAAGT GGTGGTGGAA GGTAGTCTGA GCCACTGCCT 1320
15 TTCCCAAGAA TCCCTTGTTG TGGAAβTTTC CAATGCTGGA AAAGCAGCGA βCCAGCGTTG 1380
GTGTGGTGGG CGGAGCTCCC AGTCGCATGG AGCGGTGTTC ATGGATGCAA CAGACCCTGG 1440
CTTCTGGAGT CCTCTGTGAG TGAGGGACCA ATCAAAATTA TTTTTCAAAA AGCAAAAAAA 1500
TGβCCGGCCT CGGCGGCTCA CACCTGTAAC CCCAGCACTT TGGGAGGCTG AββTGGβTGG 1560
ATCACTTGAG GTCAGGAGCT CGAGACCAGC TTGGCCAACA TGGTGAGCCC CCβTCTCTAC 1620
20 TAAAATACAA AAAAATTAGC CAGGCGTGGT GGCGGGCGCC TGTAATCCCA GCTACTTGGG 1680
AGGCTGAGGC AGGAGAATCG CTTGAATCTG GGAGGCGGAG ATTGCAGTGA GCCGAGATCC 1740
CGCCACTGCA CTCCAGCCCA GGTGACAGAβ CGAGACTCCA TCTCAAAAAA AAAAAAAAAA 1800
Seq ID NO: C434 DNA Sequence 2.D Nucleic Acid Accession ff: Eos sequence
Coding sequence: 261..2861
1 11 21 31 41 l l l l l
30 GAGCTAGCGC TCAAGCAGAG CCCAGCβCGG TGCTATCGGA CAGAGCCTGG CGAGCβCAAβ 60 CGGCGCGGGG AGCCAGCGGG GCTGAGCGCG GCCAGGGTCT GAACCCAGAT ' TTCCCAβACT 120 AGCTACCACT CCGCTTGCGC ACGCCCCGGG AGCTCGCGβC GCCTGGCGGT GAGCGACCAG 180 ACGTCCGGββ CCβCTGCGCT CCTGGCCCGC GAGGCGTGAC ACTGTCTCGG CTACAGACCC 240 AGAGGGAGCA CACTGCCAGG ATGGGAGCTG CTGGGAGGCA GβACTTCCTC TTCAAGGCCA 300
35 TGCTGACCAT CAGCTGGCTC ACTCTGACCT GCTTCCCTGG GGCCACATCC . ACAGTCGCTG 360 CTGGGTGCCC TGACCAGAGC CCTGAGTTGC AACCCTGGAA CCCTGGCCAT GACCAAGACC 420 ACCATCTGCA TATCGGCCAG GGCAAGACAC TGCTGCTCAC CTCTTCTGCC ACGGTCTATT 480 CCATCCACAT CTCAGAGGGA GGCAAGCTGG TCATTAAAGA CCACGACGAG CCGATTGTTT 540 TGCGAACCCG GCACATCCTG ATTGACAACG GAGGAGAGCT GCATβCTGGG AGTGCCCTCT 600
40 GCCCTTTCCA GGGCAATTTC ACCATCATTT TGTATGGAAG GGCTβATGAA GGTATTCAGC 660 CGGATCCTTA CTATGGTCTG AAGTACATTG GGGTTGGTAA AGGAGGCβCT CTTGAGTTGC 720 ATGGACAGAA AAAGCTCTCC TGGACATTTC TGAACAAGAC CCTTCACCCA GGTGGCATGG 780 CAGAAGGAGG CTATTTTTTT GAAAGGAβCT ββGGCCACCG TGGAβTTATT GTTCATGTCA 840 TCGACCCCAA ATCAGGCACA GTCATCCATT CTGACCGGTT TGACACCTAT AGATCCAAGA 900
45 AAGAGAβTβA ACβTCTββTC CAβTATTTGA ACGCGGTGCC CGATGGCAGG ATCCTTTCTG 960 TTGCAGTGAA TGATGAAGGT TCTCGAAATC TGGATGACAT GGCCAGGAAG GCGATGACCA 1020 AATTGGGAAG CAAACACTTC CTGCACCTTG GATTTAGACA CCCTTGGAGT TTTCTAACTβ 1080 TGAAAGGAAA TCCATCATCT TCAGTGGAAG ACCATATTGA ATATCATGGA CATCβAGGCT 1140 CTGCTGCTGC CCGGGTATTC AAATTGTTCC AGACAGAβCA TGGCGAATAT TTCAATGTTT 1200
50 CTTTGTCCAG TGAGTGGGTT CAAGACGTGG AGTGGACβGA GTGGTTCβAT CATGATAAAG 1260 TATCTCAGAC TAAAGGTGGG GAGAAAATTT CAGACCTCTG GAAAGCTCAC CCAGGAAAAA 1320 TATGCAATCG TCCCATTGAT ATACAGGCCA CTACAATGGA TGGAGTTAAC CTCAGCACCG 1380 AGGTTGTCTA CAAAAAAGGC CAGGATTATA GGTTTGCTTG CTACGACCGG GGCAGAGCCT 1440 GCCGGAGCTA CCGTGTACGG TTCCTCTGTG GGAAGCCTGT GAGGCCCAAA CTCACAGTCA 1500
55 CCATTGACAC CAATGTGAAC AβCACCATTC TGAACTTGGA GGATAATGTA CAGTCATGGA 1560 AACCTGGAGA TACCCTGGTC ATTGCCAGTA CTGATTACTC CATGTACCAG GCAGAA6AGT 1620 TCCAGGTCCT TCCCTGCAβA TCCTGCGCCC CCAACCAGGT CAAAGTβGCA GGGAAACCAA 1680 TGTACCTGCA CATCGββGAG GAGATAGACG GCGTGGACAT GCGβGCGGAG GTTGGGCTTC 1740 TGAGCCGGAA CATCATAGTG ATGGGGGAGA TGGAGGACAA ATGCTACCCC TACAGAAACC 1800
60 ACATCTGCAA TTTCTTTGAC TTCGATACCT TTGβGGGCCA CATCAAGTTT GCTCTGGGAT 1860 TTAAGGCAGC ACACTTGGAG GGCACGGAGC TGAAGCATAT GGGACAGCAG CTGGTGGGTC 1920 AGTACCCGAT TCACTTCCAC CTGGCCGGTG ATGTAGACGA AAGGGβAGGT TATGACCCAC 1980 CCACATACAT CAGGGACCTC TCCATCCATC ATACATTCTC TCGCTGCGTC ACAGTCCATG 2040 GCTCCAATGG CTTGTTGATC AAGGACGTTG TGGGCTATAA CTCTTTGGGC CACTGCTTCT 2100
65 TCACGGAAGA TGGGCCGGAG GAACGCAACA CTTTTGACCA CTGTCTTGGC CTCCTTGTCA 2160 AGTCTCGAAC CCTCCTCCCC TCGGACCGTG ACAGCAAGAT GTGCAAGATG ATCACAGAGG 2220 ACTCCTACCC AGGGTACATC CCCAAGCCCA GGCAAGACTG CAATGCTGTG TCCACCTTCT 2280 GGATGGCCAA TCCCAACAAC AACCTCATCA ACTGTGCCGC TGCAGGATCT GAGGAAACTG 2340 GATTTTGGTT TATTTTTCAC CACGTACCAA CGGGCCCCTC CGTβGGAATG TACTCCCCAG 2400
70 GTTATTCAGA GCACATTCCA CTGGGAAAAT TCTATAACAA CCGAGCACAT TCCAACTACC 2460 GGGCTGGCAT GATCATAGAC AACGGAGTCA AAACCACCGA GGCCTCTGCC AAGGACAAGC 2520 GGCCGTTCCT CTCAATCATC TCTGCCAGAT ACAGCCCTCA CCAGGACGCC GACCCGCTGA 2580 AGCCCCGGGA GCCGGCCATC ATCAGACACT TCATTGCCTA CAAGAACCAG GACCACGGGG 2640 CCTGβCTGCG CGGCGβGGAT GTGTGGCTGG ACAGCTGCCA TTTCAGAGββ GAGGCTCAGG 2700
75 AAGβCTTCTT GCTTACAGGA ATGAAGGCTG βββGCATTTT GCTGβββGGA . GATGAGβCAG 2760 CCTCTGGAAT GGCTCAGGGA TTCAGCCCTC CCTGCCGCTG CCTGCTGAAG 1 CTGGTβACTA 2820 CGGGGTCGCC CTTTGCTCAC GTCTCTCTGG CCCACTCATG ATGGAGAAGT 1 βTCGTCAGAG 2880 GGβAGCAATG GGCTTTGCTβ CTTATGAGCA CAGAGGAATT CAGTCCCCAG ! GCAGCCCTGC 2940 CTCTGACTCC AAGAGG6TGA AGTCCACAGA AGTGAGCTCC TGCCTTAGGG ! CCTCATTTGC 3000
80 TCTTCATCCA GGGAACTGAG CACAGGGGGC CTCCAGGAGA CCCTAGATGT ' GCTCGTACTC 3060 CCTCGGCCTG GGATTTCAGA GCTGGAAATA TAβAAAATAT CTAGCCCAAA . GCCTTCATTT 3120 TAACAGATGG GGAAAβTGAG CCCCCAAGAT GGGAAAGAAC CACACAGCTA . AGGGAGGGCC 3180 TGGGGAGCCC CACCCTAGCC CTTGCTGCCA CACCACATTG CCTCAACAAC I CGGCCCCAGA 3240 GTGCCCAGGC ACTCCTGAGG TAGCTTCTGG AAATGGGGAC AAGTCCCCTC ! GAAGGAAAGG 3300 AAATGACTAG AGTAGAATGA CAGCTAGCAG ATCTCTTCCC TCCTGCTCCC AGCGCACACA 3360
AACCCGCCCT CCCCTTGGTG TTGGCGGTCC CTGTGGCCTT CACTTT6TTC ACTACCTGTC 3420
AGCCCAGCCT GGGTGCACAG TAGCTGCAAC TCCCCATTGG TGCTACCTGG CTCTCCTGTC 3480
TCTGCAGCTC TACAGGTGAG GCCCAGCAGA GGGAGTAGGG CTCGCCATGT TTCTGGTβAβ 3540
CCAATTTGGC TGATCTTGGG TGTCTGAACA GCTATTGGGT CCACCCCAGT CCCTTTCAβC 3600
TGCTGCTTAA TGCCCTGCTC TCTCCCTGGC CCACCTTATA GAβAβCCCAA AGAGCTCCTG 3660
TAAGAGGGAG AACTCTATCT GTGGTTTATA ATCTTGCACG AβGCACCAGA GTCTCCCTGG 3720
GTCTTGTGAT GAACTACATT TATCCCCTTT CCTGCCCCAA CCACAAACTC TTTCCTTCAA 3780
AGAGGGCCTβ CCTGGCTCCC TCCACCCAAC TGCACCCATβ AGACTCGGTC CAAGAGTCCA 3840
TTCCCCAGGT GGGAGCCAAC TGTCAGGGAG GTCTTTCCCA CCAAACATCT TTCAGCTGCT 3900
GGGAβGTGAC CATAGβGCTC TGCTTTTAAA GATATGGCTG CTTCAAAGGC CAGAGTCACA 3960
GGAAββACTT CTTCCAGGGA GATTAGTGGT GATGGAGAGG AGAGTTAAAA TGACCTCATG 4020
TCCTTCTTGT CCACGGTTTT GTTGA6TTTT CACTCTTCTA ATGCAAGGGT CTCACACTGT 4080
GAACCACTTA GGATCTGATC ACTTTCAGGT GGCCAGGAAT GTTGAATGTC TTTGGCTCAG 4140
TTCATTTAAA AAAGATATCT ATTTGAAAGT TCTCAGAGTT GTACATATGT TTCACAGTAC 4200
AGGATCTβTA CATAAAAGTT TCTTTCCTAA ACCATTCACC AAGAGCCAAT ATCTAGGCAT 4260
TTTCTTGGTA GCACAAATTT TCTTATTGCT TAGAAAATTG TCCTCCTTGT TATTTCTGTT 4320
TGTAAβACTT AAGTβAGTTA GGTCTTTAAG GAAAGCAACG CTCCTCTGAA ATβCTTGTCT 4380
TTTTTCTCTT GCCGAAATAG CTGGTCCTTT TTCGGGAGTT AGATGTATAG AGTGTTTGTA 4440
TGTAAACATT TCTTGTAGGC ATCACCATGA ACAAAGATAT ATTTTCTATT TATTTATTAT 4500
ATGTGCACTT CAAGAAGTCA CTGTCAGAGA AATAAAGAAT TGTCTTAAAT GTCATGATTG 4560
GAGATGTCCT TTGCATTGCT TGGAAGGGGT GTACCTAGAG CCAAGGAAAT TGGCTCTGβT 4620
TTGGAAAAAT TTTGCTCTTA TTATAGTAAA CATACAAAGG ATGTCAAAAA AAAAAAAAAA 4680
AAAAAAAAAA AAAAAAAAAA AA 4702
Seq ID NO: C217 Protein Sequence Protein Accession ft: NP 005805.1
31
MVGKMWPVLW TLCAVRVTVD AISVETPQDV LRASQGKSVT LPCTYHTSTS SREGLIQ DK 60
LLLTHTERW IWPFSNKNYI HGELYKNRVS ISNNAEQSDA SITIDQLTMA DNGTYECSVS 120
LMSDLEGNTK SRVRLLVLVP PSKPECβlEG ETIIGNNIQL TCQSKEGSPT PQYSWKRYNI 180
LNQEQPLAQP ASGQPVSLKN ISTDTSGYYI CTSSNEEGTQ FCNITVAVRS PSMNVALYVG 240
IAVGWAALI IIGIIIYCCC CRGKDDNTED KEDARPNREA YEEPPEQLRE LSREREEEDD 300
YRQEEQRSTG RESPDHLDQ 319
Seq ID NO: C218 Protein Sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MGSRTPESPL HAVQLRWGPR RRPPLLPLLL LLLPPPPRVG GFNLDAEAPA VLSGPPGSFF 60 GFSVEFYRPG TDGVSVLVGA PKANTSQPGV LQGGAVYLCP WGASPTQCTP IEFDSKGSRL 120 LESSLSSSEG EEPVEYKSLQ WFGATVRAHG SSILACAPLY SWRTEKEPLS DPVGTCYLST 180 DNFTRILEYA PCRSDFSWAA GQGYCQGGFS AEFTKTGRW LGGPGSYFWQ GQILSATQEQ 240 IAESYYPEYL INLVQGQLQT RQASSIYDDS YLGYSVAVGE FSGDDTEDFV AGVPK6NLTY 300 GYVTILNGSD IRSLYNFSGE QMASYFGYAV AATDVNGDGL DDLLVGAPLL MDRTPDGRPQ 360 EVGRVYVYLQ HPAGIEPTPT LTLTGHDEFG RFGSSLTPLG DLDQDGYNDV AIGAPFGGET 420 QQGWFVFPG GPGGLGSKPS QVLQPLWAAS HTPDFFGSAL RGβRDLDGNG YPDLIVGSFG 480 VDKAWYRGR PIVSASASLT IFPAMFNPEE RSCSLEGNPV ACINLSFCLN ASGKHVADSI 540 GFTVELQLDW QKQKGGVRRA LFLASRQATL TQTLLIQNGA REDCREMKIY LRNESEFRDK 600 LSPIHIALNF SLDPQAPVDS HGLRPALHYQ SKSRIEDKAQ ILLDCGEDNI CVPDLQLEVF 660 βEQNHVYLGD KNALNLTFHA QNVGEGGAYE AELRVTAPPE AEYSGLVRHP GNFSSLSCDY 720 FAVNQSRLLV CDLGNPMKAG ASLWGGLRFT VPHLRDTKKT IQFDFQILSK NLNNSQSDW 780 SFRLSVEAQA QVTLNGVSKP EAVLFPVSDH HPRDQPQKEE DLGPAVHHVY ELINQGPSSI 840 SQGVLELSCP QALEGQQLLY VTRVTGLNCT TNHPINPKGL ELDPEGSLHH QQKREAPSRS 900 SASSGPQILK CPEAECFRLR CELGPLHQQE SQSLQLHFRV WAKTFLQREH QPFSLQCEAV 960 YKALKMPYRI LPRQLPQKER QVATAVQWTK AEGSYGVPLW IIILAILFGL LLLGLLIYIL 1020 YKLGFFKRSL PYGTAMEKAQ LKPPATSDA 1049
Seq ID NO: C219 Protein Sequence Protein Accession ft: NP 002412.1
1 11 21 31 41 51
1 1 | 1 1 1 11 11 11 MHSFPPLLLL LFWGWSHSF PATLETQEQD VDLVQKYLEK YYNLKNDGRQ VEKRRNSGPV 60
VEKLKQMQEF FGLKVTGKPD AETLKVMKQP RCGVPDVAQF VLTEGNPRWE QTHLTYRIEN 120
YTPDLPRADV DHAIEKAFQL WSNVTPLTFT KVSEGQADIM ISFVRGDHRD NSPFDGPββN 180
LAHAFQPGPG IGGDAHFDED ERWTNNFREY NLHRVAAHEL GHSLGLSHST DIGALMYPSY 240
TFSGDVQLAQ DDIDGIQAIY GRSQNPVQPI GPQTPKACDS KLTFDAITTI RGEVMFFKDR 300
FYMRTNPFYP EVELNFISVF WPQLPNGLEA AYEFADRDEV RFFKGNKYWA VQGQNVLHGY 360
PKDIYSSFGF PRTVKHIDAA LSEENTGKTY FFVANKYWRY DEYKRSMDPG YPKMIAHDFP 420
GIGHKVDAVF MKDGFFYFFH GTRQYKFDPK TKRILTLQKA NSWFNCRKN 469
Seq ID NO: C220 Protein Sequence Protein Accession ff : Eos sequence
1 11 21 31 41 51
I I I I I I
MHSFPPLLLL LFWGWSHSF PATLETQEQD VDLVQKYLEK YYNLKNDGRQ VEKRRNSGPV 60 VEKLKQMQEF FGLKVTGKPD AETLKVMKQP RCGVPDVAQF VLTEGNPRWE QTHLTYRIEN 120 YTPDLPRADV DHAIEKAFQL WSNVTPLTFT KVSEGQADIM ISFVRGDHRD NSPFDGPGGN 180 LAHAFQPGPG IGβDAHFDED ERWTNNFREY NLHRVAAHAL βHSLGLSHST DIGALMYPSY 240 TFSGDVQLAQ DDIDGIQAIY GRSQNPVQPI GPQTPKACDS KLTFDAITTI RGEVMFFKDR 300
FYMRTNPFYP EVELNFISVF WPQLPNGLEA AYEFADRDEV RFFKGNKYWA VQGQNVLHGY 360
PKDIYSSFGF PRTVKHIDAA LSEENTGKTY FFVANKYWRY DEYKRSMDPG YPKMIAHDFP 420 βlGHKVDAVF MKDGFFYFFH GTRQYKFDPK TKRILTLQKA NSWFNCRKN 469
Seq ID NO: C221 Protein Sequence Protein Accession ft : NP 055146.1
11 21 31 41 51
I I I I I
MVRKPWSTI SKGGYLQGNV NGRLPSLGNK EPPGQEKVQL KRKVTLLRGV SIIIGTIIGA 60 GIFISPKGVL QNTGSVGMSL TIWTVCGVLS LFGALSYAEL GTTIKKSGGH YTYILEVFGP 120 LPAFVRVWVE LLIIRPAATA VISLAFGRYI LEPFFIQCEI PELAIKLITA VGITWMVLN 180 SMSVSWSARI QIFLTFCKLT AILIIIVPGV MQLIKGQTQN FKDAFSGRDS SITRLPLAFY 240 YGMYAYAβWF YLNFVTEEVE NPEKTIPLAI CISMAITIGV YVLTNVAYFT TINAEELLLS 300 NAVAVTFSER LLGNFSLAVP IFVALSCFGS MNGGVFAVSR LFYVASREGH LPEILSMIHV 360 RKHTPLPAVI VLHPLTMIML FSGDLDSLLN FLSFARWLFI GLAVAβLIYL RYKCPDMHRP 420 FKVPLFIPAL FSFTCLFMVA LSLYSDPFST GIGFVITLTG VPAYYLFIIW DKKPRWFRIM 480 SEKITRTLQI ILEWPEEDK L 501
Seq ID NO: C222 Protein Sequence Protein Accession ft: NP 003237.1
11 21 31 41 51
I I I I I
MGLAWβLGVL FLMHVCGTNR IPESGGDNSV FDIFELTGAA RKGSGRRLVK GPDPSSPAFR 60 IEDANLIPPV PDDKFQDLVD AVRAEKGFLL LASLRQMKKT RβTLLALERK DHSGQVFSW 120 SNGKAGTLDL SLTVQGKQHV VSVEEALLAT βQWKSITLFV QEDRAQLYID CEKMENAELD 180 VPIQSVFTRD LASIARLRIA KGGVNDNFQG VLQNVRFVFβ TTPEDILRNK GCSSSTSVLL 240 TLDNNWNGS SPAIRTNYIG HKTKDLQAIC GISCDELSSM VLELRGLRTI VTTLQDSIRK 300 VTEENKELAN ELRRPPLCYH NGVQYRNNEE WTVDSCTECH CQNSVTICKK VSCPIMPCSN 360 ATVPDGECCP RCWPSDSADD GWSPWSEWTS CSTSCGNGIQ QRGRSCDSLN NRCEGSSVQT 420 RTCHIQECDK RFKQDGGWSH WSPWSSCSVT CGDGVITRIR LCNSPSPQMN GKPCEGEARE 480 TKACKKDACP INGGWGPWSP WDICSVTCGG GVQKRSRLCN NPAPQFGGKD CVGDVTENQI 540 CNKQDCPIDG CLSNPCFAGV KCTSYPDGSW KCGACPPGYS GNGIQCTDVD ECKEVPDACF 600 NHNGEHRCEN TDPGYNCLPC PPRFTGSQPF GQGVEHATAN KQVCKPRNPC TDGTHDCNKN 660 AKCNYLGHYS DPMYRCECKP GYAGNGIICG EDTDLDGWPN ENLVCVANAT YHCKKDNCPN 720 LPNSGQEDYD KDGIGDACDD DDDNDKIPDD RDNCPFHYNP AQYDYDRDDV GDRCDNCPYN 780 HNPDQADTDN NGEGDACAAD IDβDGILNER DNCQYVYNVD QRDTDMDGVG DQCDNCPLEH 840 NPDQLDSDSD RIGDTCDNNQ DIDEDGHQNN LDNCPYVPNA NQADHDKDGK GDACDHDDDN 900 DGIPDDKDNC RLVPNPDQKD SDGDGRGDAC KDDFDHDSVP DIDDICPENV DISETDFRRF 960 QMIPLDPKGT SQNDPNWWR HQGKELVQTV NCDPGLAVGY DEFNAVDFSβ TFFINTERDD 1020 DYAGFVFβYQ SSSRFYWMW KQVTQSYWDT NPTRAQGYSG LSVKWNSTT GPGEHLRNAL 1080 WHTGNTPGQV RTLWHDPRHI GWKDFTAYRW RLSHRPKTGF IRWMYEGKK IMADSGPIYD 1140 KTYAGGRLGL FVFSQEMVFF SDLKYECRDP 1170
Seq ID NO: C223 Protein Sequence Protein Accession ff: NP 002183.1
11 21 31 41 51
MPLLWLRGFL LASCWIIVRS SPTPGSEGHS AAPDCPSCAL AALPKDVPNS QPEMVEAVKK 60 HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVβKVGENGY VEIEDDIGRR AEMNELMEQT 120 SEIITFAESG TARKTLHFEI SKEGSDLSW ERAEVWLFLK VPKANRTRTK VTIRLFQQQK 180 HPQGSLDTGE EAEEVGLKGE RSELLLSEKV VDARKSTWHV FPVSSSIQRL LDQGKSSLDV 240 RIACEQCQES GASLVLLGKK KKKEEEGEGK KKGGGEGGAG ADEEKEQSHR PFLMLQARQS 300 EDHPHRRRRR GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG 360 TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV 420 EECGCS 426
Seq ID NO: C224 Protein Sequence Protein Accession ft: NP 000086.1
11 21 31 41 51
I I I I I
MVPDTACVLL LTLAALGASG QGQSPLGSDL GPQMLRELQE TNAALQDVRD WLRQQVREIT 60 FLKNTVMECD ACGMQQSVRT GLPSVRPLLH CAPGFCFPGV ACIQTESGGR CGPCPAGFTβ 120 NGSHCTDVNE CNAHPCFPRV RCINTSPGFR CEACPPGYSG PTHQGVGLAF AKANKQVCTD 180 INECETGQHN CVPNSVCINT RGSFQCGPCQ PGFVGDQASG CQRGAQRFCP DGSPSECHEH 240 ADCVLERDGS RSCVCRVGWA GNGILCGRDT DLDGFPDEKL RCPEPQCRKD NCVTVPNSGQ 300 EDVDRDGIGD ACDPDADGDG VPNEKDNCPL VRNPDQRNTD EDKWGDACDN CRSQKNDDQK 360 DTDQDGRGDA CDDDIDGDRI RNQADNCPRV PNSDQKDSDG DGIGDACDNC PQKSNPDQAD 420 VDHDFVGDAC DSDQDQDGDG HQDSRDNCPT VPNSAQEDSD HDGQGDACDD DDDNDGVPDS 480 RDNCRLVPNP GQEDADRDGV GDVCQDDFDA DKWDKIDVC PENAEVTLTD FRAFQTWLD 540 PEGDAQIDPN WWLNQGREI VQTMNSDPGL AVGYTAFNGV DFEGTFHVNT VTDDDYAβFI 600 FGYQDSSSFY WMWKQMEQT YWQANPFRAV AEPGIQLKAV KSSTGPGEQL RNALWHTGDT 660 ESQVRLLWKD PRNVGWKDKK SYRWFLQHRP QVGYIRVRFY EGPELVADSN WLDTTMRGG 720 RLGVFCFSQE NIIWANLRYR CNDTIPEDYE THQLRQA 757
Seq ID NO: C225 Protein Sequence Protein Accession ft: NP 612464
21 MRPQGPAASP QRLRGLLLLL LLQLPAPSSA SEIPKGKQKA QLRQREWDL YNGMCLQGPA 60
GVPGRDGSPG ANGIPGTPGI PβRDGFKGEK GECLRESFEE SWTPNYKQCS WSSLNYGIDL 120
GKIAECTFTK MRSNSALRVL FSGSLRLKCR NACCQRWYFT FNGAECSGPL PIEAIIYLDQ 180
GSPEMNSTIN IHRTSSVEGL CEGIβAGLVD VAIWVGTCSD YPKGDASTGW NSVSRIIIEE 240
LPK 243
Seq ID NO: C226 Protein Sequence Protein Accession ff: NP 003216.1
MATMENKVIC ALVLVSMLAL GTLAEAQTET CTVAPRERQN CGFPGVTPSQ CANKGCCFDD 60 TVRGVPWCFY PNTIDVPPEE ECEF 84 Seq ID NO: C227 Protein Sequence Protein Accession ff: NP 056234.1
11 21 31 51
I I
MPKRAHWGAL SWLILLWGH PRVALACPHP CACYVPSEVH CTFRSLASVP AGIARHVERI 60
NLGFNSIQAL SETSFAGLTK LELLMIHGNE IPSIPDβALR DLSSLQVFKF SYNKLRVITG 120
QTLQGLSNLM RLHIDHNKIE FIHPQAFNGL TSLRLLHLEβ NLLHQLHPST FSTFTFLDYF 180
RLSTIRHLYL AENMVRTLPA SMLRNMPLLE NLYLQGNPWT CDCEMRWFLE WDAKSRGILK 240
CKKDKAYEGG QLCAMCFSPK KLYKHEIHKL KDMTCLKPSI ESPLRQNRSR SIEEEQEQEE 300
DGGSQLILEK FQLPQWSISL NMTDEHGNMV NLVCDIKKPM DVYKIHLNQT DPPDIDINAT 360
VALDFECPMT RENYEKLWKL lAYYSEVPVK LHRELMLSKD PRVSYQYRQD ADEEALYYTβ 420
VRAQILAEPE WVMQPSIDIQ LNRRQSTAKK VLLSYYTQYS QTISTKDTRQ ARGRSWVMIE 480
PSGAVQRDQT VLEGβPCQLS CNVKASESPS IFWVLPDGSI LKAPMDDPDS KFSILSSGWL 540
RIKSMEPSDS βLYQCIAQVR DEMDRMVYRV LVQSPSTQPA EKDTVTIGKN PGESVTLPCN 600
ALAIPEAHLS WILPNRRIIN DLANTSHVYM LPNGTLSIPK VQVSDSGYYR CVAVNQQGAD 660
HFTVGITVTK KβSGLPSKRG RRPGAKALSR VREDI EDEG GSGMGDEENT SRRLLHPKDQ 720
EVFLKTKDDA INGDKKAKKG RRKLKLWKHS EKEPETNVAE GRRVFESRRR INMANKQINP 780
ERWADILAKV RGKNLPKGTE VPPLIKTTSP PSLSLEVTPP FPAVSPPSAS PVQTVTSAEE 840
SSADVPLLGE EEHVLGTISS ASMGLEHNHN GVILVEPEVT STPLEEWDD LSEKTEEITS 900
TEGDLKGTAA PTLISEPYEP SPTLHTLDTV YEKPTHEETA TEGWSAADVG SSPEPTSSEY 960
EPPLDAVSLA ESEPMQYFDP DLETKSQPDE DKMKEDTFAH LTPTPTIWVN DSSTSQLFED 1020
STIGEPGVPG QSHLQGLTDN IHLVKSSLST QDTLLIKKβM KEMSQTLQGG NMLEGDPTHS 1080
RSSESEGQES KSITLPDSTL GIMSSMSPVK KPAETTVGTL LDKDTTTVTT TPRQKVAPSS 1140
TMSTHPSRRR PNGRRRLRPN KFRHRHKQTP PTTFAPSETF STQPTQAPDI KISSQVESSL 1200
VPTAWVDNTV NTPKQLEMEK NAEPTSKGTP RRKHGKRPNK HRYTPSTVSS RASGSKPSPS 1260
PENKHRNIVT PSSETILLPR TVSLKTEGPY DSLDYMTTTR KIYSSYPKVQ ETLPVTYKPT 1320
SDGKEIKDDV ATNVDKHKSD ILVTGESITN AIPTSRSLVS TMGEFKEESS PVGFPGTPTW 1380
NPSRTAQPGR LQTDIPVTTS GENLTDPPLL KELEDVDFTS EFLSSLTVST PFHQEEAβSS 1440
TTLSSIKVEV ASSQAETTTL DQDHLETTVA ILLSETRPQN HTPTAARMKE PASSSPSTIL 1500
MSLGQTTTTK PALPSPRISQ ASRDSKENVF LNYVGNPETE ATPVNNEGTQ HMSGPNELST 1560
PSSDRDAFNL STKLELEKQV FGSRSLPRGP DSQRQDGRVH ASHQLTRVPA KPILPTATVR 1620
LPEMSTQSAS RYFVTSQSPR HWTNKPEITT YPSGALPENK QFTTPRLSST TIPLPLHMSK 1680
PSIPSKFTDR RTDQFNGYSK VFGNNNIPEA RNPVGKPPSP RIPHYSNGRL PFFTNKTLSF 1740
PQLGVTRRPQ IPTSPAPVMR ERKVIPGSYN RIHSHSTFHL DFGPPAPPLL HTPQTTGSPS 1800
TNLQNIPMVS STQSSISFIT SSVQSSGSFH QSSSKFFAGG PPASKFWSLG EKPQILTKSP 1860
QTVSVTAETD TVFPCEATGK PKPFVTWTKV STGALMTPNT RIQRFEVLKN GTLVIRKVQV 1920
QDRGQYMCTA SNLHGLDRMV VLLSVTVQQP QILASHYQDV TVYLGDTIAM ECLAKGTPAP 1980
QISWIFPDRR VWQTVSPVES RITLHENRTL SIKEASFSDR GVYKCVASNA AGADSLAIRL 2040
HVAALPPVIH QEKLENISLP PGLSIHIHCT AKAAPLPSVR WVLGDGTQIR PSQFLHGNLF 2100
VFPNGTLYIR NLAPKDSGRY ECVAANLVGS ARRTVQLNVQ RAAANARITG TSPRRTDVRY 2160
GGTLKLDCSA SGDPWPRILW RLPSKRMIDA LFSFDSRIKV FANGTLWKS VTDKDAGDYL 2220
CVARNKVGDD YWLKVDWM KPAKIEHKEE NDHKVFYGGD LKVDCVATGL PNPEISWSLP 2280
DGSLVNSFMQ SDDSGGRTKR YWFNNGTLY FNEVGMREEG DYTCFAENQV GKDEMRVRVK 2340
WTAPATIRN KTYLAVQVPY GDWTVACEA KGEPMPKVTW LSPTNKVIPT SSEKYQIYQD 2400
GTLLIQKAQR SDSGNYTCLV RNSAGEDRKT VWIHVNVQPP KINGNPNPIT TVREIAAGGS 2460
RKLIDCKAEG IPTPRVLWAF PEβWLPAPY YGNRITVHGN GSLDIRSLRK ; SDSVQLVCMA 2520
RNEGGEARLI VQLTVLEPME KPIFHDPISE KITAMAGHTI SLNCSAAGTP TPSLVWVLPN 2580
GTDLQSGQQL QRFYHKADGM LHISGLSSVD AGAYRCVARN AAβHTERLVS 1 LKVGLKPEAN 2640
KQYHNLVSII NGETLKLPCT PPGAGQGRFS WTLPNGMHLE GPQTLGRVSL , LDNGTLTVRE 2700
ASVFDRGTYV CRMETEYGPS VTSIPVIVIA YPPRITSEPT PVIYTRPGNT ' VKLNCMAMGI 2760
PKADITWELP DKSHLKAGVQ ARLYGNRFLH PQGSLTIQHA TQRDAGFYKC ! MAKNILGSDS 2820
KTTYIHVF 2828
Seq ID NO: C228 Protein Sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51 1 1 1 1 J 1 | 1 | 1 1 MPGTKLTRTβ APADYRVILK TSQEDELDVP DDISVRVMSS QSVLVSWVDP VLEKQKKWA 60
SRQYTVRYRE KGELARWDYK QIANRRVLIE NLIPDTVYEF AVRISQGERD GKWSTSVFQR 120
TPESAPTTAP ENLNVWPVNG KPTWAASWD ALPETEβKVK VCLLDTGLFS VSSFQPSAKS 180
FQNTFFHTPR LSNHLEQSPS PILETLLLPW WMVCSLGNAI FSKSGPQTβE AWDLTPKPSL 240
SLCQQECSCT QKDFSCLAYL IDIQTKQVNK DPQLEGSVFG PCFLFYFLTF MLDIGGFSFI 300
MCYEDP7VSS LTGNSLKSVA ASKADVQQNT EDNGKPEKPE PSSPSPRAPA SSQHPSVPAS 360
PQGRNAKDLL LDLKNKILAN GGAPRKPQLR AKKAEELDLQ STEITGEEEL 6SREDSPMSP 420
SDTQDQKRTL RPPSRHGHSV VAPGRTAVRA RMPALPRREβ VDKPGFSLAT QPRPGAPPSA 480
SASPAHHAST QGTSHRPSLP ASLNDNDLVD SDEDERAVGS LHPKGAFAQP RPALSPSRQS 540
PSSVLRDRSS VHPGAKPASP ARRTPHSGAA EEDSSASAPP SRLSPPHGGS SRLLPTQPHL 600
SSPLSKGGKD GEDAPATNSN APSRSTMSSS VSSHLSSRTQ VSEGAEASDG ESHGDGDRED 660 GGRQAEATAQ TLRARPASGH FHLLRHKPFA ANGRSPSRFS IGRGPRLQPS SSPQSTVPSR 720 AHPRVPSHSD SHPKLSSGIH GDEEDEKPLP ATWNDHVPS SSRQPISRGW EDLRRSPQRG 780 ASLHRKEPIP ENPKSTGADT HPQGKYSSLA SKAQDVQQST DADTEGHSPK AQPGSTDRHA 840 SPARPPAARS QQHPSVPRRM TPGRAPEQQP PPPVATSQHH PGPQSRDAGR SPSQPRLSLT 900 QAGRPRPTSQ GRSHSSSDPY TASSRGMLPT ALQNQDEDAQ GSYDDDSTEV EAQDVRAPAH 960 AARAKEAAAS LPKHQQVESP TGAGAββDHR SQRGHAASPA RPSRPGGPQS RARVPSRAAP 1020 βKSEPPSKRP LSSKSQQSVS AEDEEEEDAG FFKGGKEDLL SSSVPKWPSS STPRGGKDAD 1080 GSLAKEEREP AIALAPRGGS LAPVKRPLPP PPGSSPRASH VPSRPPPRSA ATVSPVAGTH 1140 PWPRYTTRAP PGHFSTTPML SLRQRMMHAR FRNPLSRQPA RPSYRQGYNG RPNVEGKVLP 1200 GSNGKPNβQR IINβPQβTKW WDLDRGLVL NAEGRYLQDS HGNPLRIKLG GDGRTIVDLE 1260 GTPWSPDGL PLFGQGRHGT PLANAQDKPI LSLGGKPLVG LEVIKKTTHP PTTTMQPTTT 1320 TTPLPTTTTP RPTTATTMQP TTTTTPLPTT TPRPTTATTR RTTTRRPTTT VRTTTRTTTT 1380 TTPKPTTPIP TCPPGTLERH DDDGNLIMSS NGIPECYAEE DEFSGLETDT AVPTEEAYVI 1440 YDEDYEFETS RPPTTTEPST TATTPRVIPE EGAISSFPEE EFDLAGRKRF VAPYVTYLNK 1500 DPSAPCSLTD ALDHFQVDSL DEIIPNDLKK SDLPPQHAPR NITWAVEGC HSFVIVDWDK 1560 ATPGDLVTGY LVYSASYEDF IRNKFSTQAS SVTHLPIENL KPNTRYYFKV QAQNPHGYGP 1620 ISPSVSFVTE SDNPLLWRP PGGELSGSHS LSNMIPATRT AMDGNM 1666
Seq ID NO: C229 Protein Sequence Protein Accession ff: NP 003005.1
11 21 31 41 51
MFLSILVALC LWLHLALGVR GAPCEAVRIP MCRHMPWNIT RMPNHLHHST QENAILAIEQ 60 YEELVDVNCS AVLRFFFCAM YAPICTLEFL HDPIKPCKSV CQRARDDCEP LMKMYNHSWP 120 ESLACDELPV YDRGVCISPE AIVTDLPEDV KWIDITPDMM VQERPLDVDC KRLSPDRCKC 180 KKVKPTLATY LSKNYSYVIH AKIKAVQRSG CNEVTTWDV KEIFKSSSPI PRTQVPLITN 240 SSCQCPHILP HQDVLIMCYE WRSRMMLLEN CLVEKWRDQL SKRSIQWEER LQEQRRTVQD 300 KKKTAGRTSR SNPPKPKCKP PAPKPASPKK NIKTRSAQKR TNPKRV 346
Seq ID NO: C230 Protein Sequence Protein Accession ff: NP 005931.1
11 21 31 41 51
MAPAAWLRSA AARALLPPML LLLLQPPPLL ARALPPDVHH LHAERRGPQP WHAALPSSPA 60 PAPATQEAPR PASSLRPPRC GVPDPSDGLS ARNRQKRFVL SGGRWEKTDL TYRILRFPWQ 120 LVQEQVRQTM AEALKVWSDV TPLTFTEVHE GRADIMIDFA RYWHGDDLPF DGPGGILAHA 180 FFPKTHREGD VHFDYDETWT IGDDQGTDLL QVAAHEFGHV LGLQHTTAAK ALMSAFYTFR 240 YPLSLSPDDC RGVQHLYGQP WPTVTSRTPA LGPQAGIDTN EIAPLEPDAP PDACEASFDA 300 VSTIRGELFF FKAGFVWRLR GGQLQPGYPA LASRHWQβLP SPVDAAFEDA QGHIWFFQGA 360 QYWVYDGEKP VLGPAPLTEL GLVRFPVHAA LVWGPEKNKI YFFRGRDYWR FHPSTRRVDS 420 PVPRRATDWR GVPSEIDAAF QDADGYAYFL RGRLYWKFDP VKVKALEGFP RLVGPDFFGC 480 AEPANTFL 488
Seq ID NO: C231 Protein Sequence Protein Accession ff: NP_076927
11 21 31 41 51
MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP IIVIGIIALI 60 LALAIGLGIH FDCSGKYRCR SSFKCIELIA RCDGVSDCKD GEDEYRCVRV GGQNAVLQVF 120 TAASWKTMCS DDWKGHYANV ACAQLGFPSY VSSDNLRVSS LEGQFREEFV SIDHLLPDDK 180 VTALHHSVYV REGCASGHW TLQCTACGHR RGYSSRIVGG NMSLLSQWPW QASLQFQGYH 240 LCGGSVITPL WIITAAHCVY DLYLPKSWTI QVGLVSLLDN PAPSHLVEKI VYHSKYKPKR 300 LGNDIALMKL AGPLTFNEMI QPVCLPNSEE NFPDGKVCWT SGWGATEDGG DASPVLNHAA 360 VPLISNKICN HRDVYGGIIS PSMLCAGYLT GGVDSCQGDS GGPLVCQERR LWKLVGATSF 420 GIGCAEVNKP GVYTRVTSFL DWIHEQMERD LKT 453
Seq ID NO: C232 Protein Sequence Protem Accession ft: NP 003211
11 21 31 41 51
MLWKLTDNIK Y IEDCEDRHDG T ISNGTARLPQ L IGTVGQSPYT S IAPPLSHTPN I
ADFQPPYFPP 60 PYQPIYPQSQ DPYSHVNDPY SLNPLHAQPQ PQHPGWPGQR QSQESGLLHT HRGLPHQLSG 120 LDPRRDYRRH EDLLHGPHAL SSGLGDLSIH SLPHAIEEVP HVEDPGINIP DQTVIKKGPV 180 SLSKSNSNAV SAIPINKDNL FGGWNPNEV FCSVPGRLSL LSSTSKYKVT VAEVQRRLSP 240 PECLNASLLG GVLRRAKSKN GGRSLREKLD KlβLNLPAGR RKAANVTLLT SLVEβEAVHL 300 ARDFGYVCET EFPAKAVAEF LNRQHSDPNE QVTRKNMLLA TKQICKEFTD LLAQDRSPLG 360 NSRPNPILEP GIQSCLTHFN LISHGFβSPA VCAAVTALQN YLTEALKAMD KMYLSNNPNS 420 HTDNNAKSSD KEEKHRK 437
Seq ID NO: C233 Protein Sequence Protein Accession #: NP 002979.1
1 11 21 31 41 51
I I I I I I
MKGLAAALLV LVCTMALCSC AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI 60 LLTKRGRQIC ADPNKKWVQK YISDLKLNA 89
Seq ID NO- C234 Protein Sequence Protem Accession ft: NP 004054.1 1 11 21 31 41 51
I I I I I I
MILQAHLHSL CLLMLYLATG YGQEGKFSGP LKPMTFSIYE GQEPSQIIFQ FKANPPAVTF 60
ELTGETDNIF VIEREGLLYY NRALDRETRS THNLQVAALD AMGIIVEGPV PITIEVKDIN 120
DNRPTFLQSK YEGSVRQNSR PGKPFLYVNA TDLDDPATPN GQLYYQIVIQ LPMINNVMYF 180
QINNKTGAIS LTREGSQELN PAKNPSYNLV ISVKDMGGQS ENSFSDTTSV DIIVTENIWK 240
APKPVEMVEN STDPHPIKIT QVRWNDPGAQ YSLVDKEKLP RFPFSIDQEG DIYVTQPLDR 300
EEKDAYVFYA VAKDEYGKPL SYPLEIHVKV KDINDNPPTC PSPVTVFEVQ ENERLGNSIG 360
TLTAHDRDEE NTANSFLNYR IVEQTPKLPM DGLFLIQTYA GMLQLAKQSL KKQDTPQYNL 420
TIEVSDKDFK TLCFVQINVI DINDQIPIFE KSDYGNLTLA EDTNIGSTIL TIQATDADEP 480
FTGSSKILYH IIKGDSEGRL GVDTDPHTNT GYVIIKKPLD FETAAVSNIV FKAENPEPLV 540
FGVKYNASSF AKFTLIVTDV NEAPQFSQHV FQAKVSEDVA IGTKVGNVTA KDPEGLDISY 600
SLRGDTRGWL KIDHVTGEIF SVAPLDREAG SPYRVQWAT EVGGSSLSSV SEFHLILMDV 660
NDNPPRLAKD YTGLFFCHPL SAPGSLIFEA TDDDQHLFRG PHFTFSLGSG SLQNDWEVSK 720
INGTHARLST RHTEFEEREY WLIRINDGG RPPLEGIVSL PVTFCSCVEG SCFRPAGHQT 780
GIPTVGMAVG ILLTTLLVIG IILAWFIRI KKDKGKDNVE SAQASEVKPL RS 832
Seq ID NO: C235 Protein Sequence Protein Accession ft: NP 004434.1
1 11 21 31 41 51
M IARARPPPPP SIPPPGLLPLL PIPLLLLPLLL LIPAGCRALEE TILMDTKWVTS EILAWTSHPES 60
GWEEVSGYDE AMNPIRTYQV CNVRESSQNN WLRTGFIWRR DVQRVYVELK FTVRDCNSIP 120
NIPGSCKETF NLFYYEADSD VASASSPFWM ENPYVKVDTI APDESFSRLD AGRVNTKVRS 180
FGPLSKAGFY LAFQDQGACM SLISVRAFYK KCASTTAβFA LFPETLTβAE PTSLVIAPβT 240
CIPNAVEVSV PLKLYCNGDG EWMVPVGACT CATGHEPAAK ESQCRPCPPG SYKAKQGEβP 300
CLPCPPNSRT TSPAASICTC HNNFYRADSD SADSACTTVP SPPRGVISNV NETSLILEWS 360
EPRDLGGRDD LLYNVICKKC HGAβGASACS RCDDNVEFVP RQLGLTERRV HISHLLAHTR 420
YTFEVQAVNG VSGKSPLPPR YAAVNITTNQ AAPSEVPTLR LHSSSGSSLT LSWAPPERPN 480
GVILDYEMKY FEKSEGIAST VTSQMNSVQL DGLRPDARYV VQVRARTVAG YGQYSRPAEF 540
ETTSERGSGA QQLQEQLPLI VGSATAGLVF WA VIAIV CLRKQRHGSD SEYTEKLQQY 600
IAPGMKVYID PFTYEDPNEA VREFAKEIDV SCVKIEEVIG AGEFGEVCRG RLKQPGRREV 660
FVAIKTLKVβ YTERQRRDFL SEASIMβQFD HPNIIRLEGV VTKSRPVMIL TEFMENCALD 720
SFLRLNDGQF TVIQLVGMLR GIAAGMKYLS EMNYVHRDLA ARNILVNSNL VCKVSDFβLS 780
RFLEDDPSDP TYTSSLβGKI PIRWTAPEAI AYRKFTSASD VWSYGIVMWE VMSYGERPYW 840
DMSNQDVINA VEQDYRLPPP MDCPTALHQL MLDCWVRDRN LRPKFSQIVN TLDKLIRNAA 900
SLKVIASAQS GMSQPLLDRT VPDYTTFTTV GDWLDAIKMG RYKESFVSAG FASFDLVAQM 960
TAEDLLRIGV TLAGHQKKIL SSIQDMRLQM NQTLPVQV 998
Seq ID NO: C236 Protein Sequence Protein Accession ft: NP_001795.1
1 11 21 31 41 51
M IYVGYVLDKD SIPVYPGPARP AISLGLGPANY GIPPAPPPAPP QIYPDFSSYSH VIEPAPAPPTA 60
WGAPFPAPKD DWAAAYGPGP AAPAASPASL AFGPPPDFSP VPAPPGPGPG LLAQPLGGPG 120
TPSSPGAQRP TPYEWMRRSV AAGGGGGSGK TRTKDKYRW YTDHQRLELE KEFHYSRYIT 180
IRRKSELAAN LGLTERQVKI WFQNRRAKER KVNKKKQQQQ QPPQPPMAHD ITATPAGPSL 240
GGLCPSNTSL LATSSPMPVK EEFLP 265
Seq ID NO: C237 Protein Sequence Protein Accession ff: NP_068813.1
1 11 21 31 41 51 l l l l l !
MGSDRARKGG GGPKDFGAGL KYNSRHEKVN GLEEGVEFLP VNNVKKVEKH GPGRWWLAA 60
VLIGLLLVLL GIGFLVWHLQ YRDVRVQKVF NGYMRITNEN FVDAYENSNS TEFVSLASKV 120
KDALKLLYSG VPFLGPYHKE SAVTAFSEGS VIAYYWSEFS IPQHLVEEAE RVMAEER M 180
LPPRARSLKS FWTSWAFP TDSKTVQRTQ DNSCSFGLHA RGVELMRFTT PGFPDSPYPA 240
HARCQWALRG DADSVLSLTF RSFDLASCDE RGSDLVTVYN TLSPMEPHAL VQLCGTYPPS 300
YNLTFHSSQN VLLITLITNT ERRHPGFEAT FFQLPRMSSC GGRLRKAQGT FNSPYYPGHY 360
PPNIDCTWNI EVPNNQHVKV RFKFFYLLEP GVPAGTCPKD YVEINGEKYC GERSQFWTS 420
NSNKITVRFH SDQSYTDTGF LAEYLSYDSS DPCPGQFTCR TβRCIRKELR CDGWADCTDH 480
SDELNCSCDA GHQFTCKNKF CKPLFWVCDS VNDCGDNSDE QGCSCPAQTF RCSNGKCLSK 540
SQQCNGKDDC GDGSDEASCP KVNWTCTKH TYRCLNGLCL SKGNPECDGK EDCSDGSDEK 600
DCDCGLRSFT RQARWGGTD ADEGEWPWQV SLHALGQGHI CGASLISPNW LVSAAHCYID 660
DRGFRYSDPT QWTAFLGLHD QSQRSAPGVQ ERRLKRIISH PFFNDFTFDY DIALLELEKP 720
AEYSSMVRPI CLPDASHVFP AGKAIWVTGW GHTQYGGTGA LILQKGEIRV INQTTCENLL 780
PQQITPRMMC VGFLSGGVDS CQGDSGGPLS SVEADGRIFQ AGWSWGDGC AQRNKPGVYT 840
RLPLFRDWIK ENTGV 855
Seq ID NO: C238 Protein Sequence Protein Accession #: Eos sequence
1 11 21 31 41 51
I I I I I I
MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN 60
SVGKβSFERS KHFAITVCDG LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR 120
MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180
FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240
PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300
SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SAGTTLDGFL 360 RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGβPT 420
LTGSALRQAA ERGFGSATRT GQDRPRRVW LLTESHSEDE VAGPARHARA RELLLLGVGS 480
EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540
SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600
APYLGGVGSA GTALLHIYDK VMTVQRGARP GVPKAWVLT ββRβAEDAAV PAQKLRNNGI 660
SVLWGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK RPVNLCKPSP 720
CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR FLRRP 755
Seq ID NO: C239 Protein Sequence Protein Accession # : Eos sequence
1 11 21 31 41 51 l l l l l !
MPPFLLLEAV CVFLFSRVPP SLPLQEVHVS KETIGKISAA SKMMWCSAAV DIMFLLDGSN 60 SVGKGSFERS KHFAITVCDG LDISPERVRV GAFQFSSTPH LEFPLDSFST QQEVKARIKR 120
MVFKGGRTET ELALKYLLHR GLPGGRNASV PQILIIVTDG KSQGDVALPS KQLKERGVTV 180
FAVGVRFPRW EELHALASEP RGQHVLLAEQ VEDATNGLFS TLSSSAICSS ATPDCRVEAH 240
PCEHRTLEMV REFAGNAPCW RGSRRTLAVL AAHCPFYSWK RVFLTHPATC YRTTCPGPCD 300
SQPCQNGGTC VPEGLDGYQC LCPLAFGGEA NCALKLSLEC RVDLLFLLDS SACTTLDGFL 360
RAKVFVKRFV RAVLSEDSRA RVGVATYSRE LLVAVPVGEY QDVPDLVWSL DGIPFRGGPT 420
LTGSALRQAA ERGFGSATRT GQDRPRRVW LLTESHSEDE VAGPARHARA RELLLLGVGS 480
EAVRAELEEI TGSPKHVMVY SDPQDLFNQI PELQGKLCSR QRPGCRTQAL DLVFMLDTSA 540
SVGPENFAQM QSFVRSCALQ FEVNPDVTQV GLWYGSQVQ TAFGLDTKPT RAAMLRAISQ 600
APYLGGVGSA GTALLHIYDK VMTVQRGARP GVPKAWVLT GGRGAEDAAV PAQKLRNNGI 660
SVLWGVGPV LSEGLRRLAG PRDSLIHVAA YADLRYHQDV LIEWLCGEAK QPVNLCKPSP 720
CMNEGSCVLQ NGSYRCKCRD GWEGPHCENR EWSSCSVCVS QGWILETPLR HMAPVQEGSS 780
RTPPSNYREG LGTEMVPTFW NVCAPGP 807
Seq ID NO : C240 Protein Sequence Protein Accession ff : XP_097386. 1
1 11 21 31 41 51
I I I I I I
MPKSEPLGCL SPASRAPGSA AATGAWLPAA SGGPGPLβPP CTCPPRSLGR GRAGSRAGSS 60
PSGCVCVS6I LRWSVGDPA SRRWVDLDSN SEDLSLLLTP MIVGTCGVGβ βWARGWVPAQ 120
EKEVAEGSGH AGRGNGRRLQ RVYGARSWIL GRKPCLQRLL PASGGPVQPQ PCPSPATACR 180
WGFKFGVAFW GAAQHPPLCR LGGGRAVPSA TRTLDGF 217
Seq ID NO : C241 Protein Sequence Protein Accession # : CAC03433
1 11 21 31 41 51
I I I I I I
MLSSTDFTFA SWELWRVDH PNEEQQKDVT LRVSGDLHVG GVMLKLVEQI NISQDWSDFA 60
LWWEQKHCWL LKTHWTLDKY GVQADAKLLF TPQHKMLRLR LPNLKMVRLR VSFSAWFKA 120
VSDICKILNI RRSEELSLLK PSGDYFKKKK KKDKMNKEPI IEDILNLESS PTASGSSVSP 180
GLYSKTMTPI YDPINGTPAS STMTWFSDSP LTEQNCSILA FSQPPQSPEA LADMYQPRSL 240
VDKAKLNAGW LDSSRSLMEQ GIQEDEQLLL RFKYYSFFDL NPKYDAVRIN QLYEQARWAI 300
LLEEIDCTEE EMLIFAALQY HISKLSLSAE TQDFAGESEV DEIEAALSNL EVTLEββKAD 360
SLLEDITDIP KLADNLKLFR PKKLLPKAFK QYWFIFKDTS IAYFKNKELE QβEPLEKLNL 420
RGCEWPDVN VAGRKFGIKL LIPVADGMNE MYLRCDHENQ YAQWMAACML ASKGKTMADS 480
SYQPEVLNIL SFLRMKNRNS ASQVASSLEN MDMNPECFVS PRCAKKHKSK QLAARILEAH 540
QNVAQMPLVE AKLRFIQAWQ SLPEFGLTYY LVRFKGSKKD DILGVSYNRL IKIDAATGIP 600
VTTWRFTNIK QWNVNWETRQ WIEFDQNVF TAFTCLSADC KIVHEYIGGY IFLSTRSKDQ 660
NETLDEDLFH KLTGGQD 677
Seq ID NO : C242 DNA Sequence Nucleic Acid Accession # : NM_005170 Coding sequence : 337 . . 918
1 11 21 31 41 51
I I I I I I
GGGCGTGAGA AAGGCGACGG CGGCGGCGCG GAGGAGGGTT ATCTATACAT TTAAAAACCA 60
GCCGCCTβCG CCGCGCCTGC GGAGACCTGG GAβAGTCCGβ CCGCACGCGC GGGACACGAG 120
CGTCCCACGC TCCCTGGCGC GTACGβCCTG CCACCACTAG GCCTCCTATC CCCGGGCTCC 180
AGACGACCTA GGACGCGTGC CCTGGGGAGT TGCCTGGCGG CGCCGTGCCA GAAGCCCCCT 240
TGGGβCGCCA CAGTTTTCCC CGTCβCCTCC GGTTCCTCTG CCTβCACCTT CCTGCGGCGC 300
GCCGGGACCT GGAGCGGGCG GGTGGATGCA GGCGCGATGG ACGβCGGCAC ACTGCCCAGG 360
TCCGCβCCCC CTGCGCCCCC CGTCCCTGTC GGCTGCGCTG CCCGGCGGAG ACCCGCCTCC 420
CCβGAACTGT TGCGCTGCAG CCGGCGGCGG CGACCGGCCA CCGCAGAGAC CGGAGGCGGC 480
GCAGCGGCCG TAGCGCGGCG CAATGAGCGC GAGCGCAACC GCGTGAAGCT GGTGAACTTG 540
GGCTTCCAGG CGCTGCGGCA GCACGTβCCβ CACGGCGGCG CCAGCAAGAA GCTGAGCAAG 600
GTGGAGACGC TGCGCTCAGC CCTββAGTAC ATCCGCGCGC TGCAGCGCCT GCTGGCCGAG 660
CACGACGCCG TGCGCAACGC GCTGGCGGGA GGGCTGAGGC CGCAGGCCGT GCGGCCGTCT 720
GCGCCCCCCG GGCCGCCAGG GACCACCCCG GTCGCCGCCT CGCCCTCCCG CGCTTCTTCG 780
TCCCCGGGCC GCGGGGGCAG CTCGGAGCCC GGCTCCCCGC GTTCCGCCTA CTCGTCGGAC 840
GACAGCGGCT GCGAAGGCGC GCTGAGTCCT GCGGAGCGCG AGCTACTCGA CTTCTCCAGC 900
TGGTTAGGGG GCTACTGAGC GCCCTCGACC TA 932
Seq ID NO : C243 Protein Sequence Protein Accession # : NP_060233 .1
1 11 21 31 41 51 MSGGHQLQLA ALWPWLLMAT LQAGFGRTGL VLAAAVESER SAEQKAVIRV IPLKMDPTGK 60
LNLTLEGVFA GVAEITPAEG KLMQSHPLYL CNASDDDNLE PGFISIVKLE SPRRAPRPCL 120
SLASKARMAG ERGASAVLFD ITEDRAAAEQ LQQPLGLTWP WLIWGNDAE KLMEFVYKNQ 180
KAHVRIELKE PPAWPDYDVW ILMTWGTIF VIILASVLRI RCRPRHSRPD PLQQRTAWAI 240
SQLATRRYQA SCRQARGEWP DSGSSCSSAP VCAICLEEFS EGQELRVISC LHEFHRNCVD 300
PWLHQHRTCP LCVFNITEGD SFSQSLGPSR SYQEPGRRLH LIRQHPGHAH YHLPAAYLLG 360
PSRSAVARPP RPGPFLPSQE PGMGPRHHRF PRAAHPRAPβ EQQRLAGAQH PYAQGWGMSH 420
LQSTSQHPAA CPVPLRRARP PDSSGSβESY CTERSGYLAD GPASDSSSGP CHGSSSDSW 480
NCTDISLQGV HGSSSTFCSS LSSDFDPLVY CSPKGDPQRV DMQPSVTSRP RSLDSWPTG 540
ETQVSSHVHY HRHRHHHYKK RFQWHGRKPG PETGVPQSRP PIPRTQPQPE PPSPDQQVTG 600
SNSAAPSGRL SNPQCPRALP EPAP6PVDAS SICPSTSSLF NLQKSSLSAR HPQRKRRGGP 660
SEPTPGSRPQ DATVHPACQI FPHYTPSVAY PWSPEAHPLI CGPPGLDKRL LPETPGPCYS 720
NSQPVWLCLT PRQPLEPHPP GEGPSEWSSD TAEGRPCPYP HCQVLSAQPG SEEELEELCE 780
QAV 783
Seq ID NO: C244 DNA Sequence Nucleic Acid Accession ft: NM_004289 Coding sequence: 493..1695
60
120
Figure imgf001343_0001
180 βAGAATGGGG TACTAAGAGA AAAGCACGAA GCTGTGGATC ATAGTTCCCA GCATGAGGAA 240
AATGAAGAAA GGGTGTCAGC CCAGAAGGAG AACTCACTTC AβCAβAATGA TGATGATGAA 300
AACAAAATAG CAGAGAAACC TGACTGGGAG βCAGAAAAGA CCACTGAATC TAGAAATGAG 360
AGACATCTGA ATGGβACAGA TACTTCTTTC TCTCTGGAAβ ACTTATTCCA GTTGCTTTCA 420
TCACAGCCTG AAAATTCACT GGAGGGCATC TCATTGGGAβ ATATTCCTCT TCCAGGCAGT 480
ATCAGTGATG GCATGAATTC TTCAGCACAT TATCATβTAA ACTTCAGCCA GβCTATAAGT 540
CAGGATGTGA ATCTTCATGA GGCCATCTTG CTTTCTCCCA ACAATACATT TAGAAGAGAT 600
CCAACAGCAA GGACTTCACA GTCACAAGAA CCATTTCTGC AGTTAAATTC TCATACCACC 660
AATCCTGAGC AAACCCTTCC TGGAACTAAT TTGACAGGAT TTCTTTCACC ββTTβACAAT 720
CATATGAGGA ATCTAACAAG CCAAGACCTA CTGTATGACC TTGACATAAA TATATTTGAT 780
GAGATAAACT TAATGTCATT GGCCACAGAA GACAACTTTG ATCCAATCGA TGTTTCTCAG 840
CTTTTTCATG AACCAGATTC TGATTCTGGC CTTTCTTTAβ ATTCAAGTCA CAATAATACC 900
TCTGTCATCA AβTCTAATTC CTCTCACTCT GTGTGTGATG AAGGTGCTAT AGGTTATTGC 960
ACTGACCATG AATCTAβTTC CCATCATGAC TTAGAAGGTG CTGTAGGTGG CTACTACCCA 1020
GAACCCAGTA AGCTTTGTCA CTTGGATCAA AGTGATTCTG ATTTCCATGG AGATCTTACA 1080
TTTCAACACG TATTTCATAA CCACACTTAC CACTTACAGC CAACTGCACC AGAATCTACT 1140
TCTGAACCTT TTCCGTGGCC TGGGAAGTCA CAGAAGATAA ββAGTAGATA CCTTGAAGAC 1200
ACAGATAGAA ACTTGAβCCG TGATGAACAG CGTGCTAAAG CTTTGCATAT CCCTTTTTCT 1260
GTAGATGAAA TTGTCGGCAT GCCTGTTGAT TCTTTCAATA GCATGTTAAG TAGATATTAT 1320
CTGACAGACC TACAAGTCTC ACTTATCCGT GACATCAGAC GAAGAGGGAA AAATAAAGTT 1380
GCTβCGCAGA ACTGTCGTAA ACGCAAATTG GACATAATTT TGAATTTAGA AβATGATGTA 1440
TGTAACTTGC AAGCAAAGAA GGAAACTCTT AAGAGAGAGC AAGCACAATG TAACAAAGCT 1500
ATTAACATAA TGAAACAGAA ACTGCATGAC CTTTATCATG ATATTTTTAG TAGATTAAGA 1560
GATGACCAAG GTAGGCCAGT CAATCCCAAC CACTATGCTC TCCAGTβTAC CCATGATGβA 1620
AGTATCTTGA TAGTACCCAA AGAACTGGTG GCCTCAGGCC ACAAAAAGGA AACCCAAAAβ 1680
GGAAAGAGAA AGTGAβAAGA AACTGAAGAT GGACTCTATT ATGTGAAGTA GTAATGTTCA 1740
GAAACTGATT ATTTGGATCA GAAACCATTG AAACTGCTTC AAGAATTCTA TCTTTAAGTA 1800
CTGCTACTTG AATAACTCAG TTAACGCTGT TTTGAAGCTT ACATGGACAA ATGTTTAGGA 1860
CTTCAAGATC ACACTTGTGG GCAATCTGGG GGAGCCACAA CTTTTCATGA AGTGCATTCT 1920
ATACAAAATT CATAGTTATG TCCAAAGAAT AGGTTAACAT GAAAACCCAG TAAGACTTTC 1980
CATCTTGGCA GCCATCCTTT TTAAGAGTAA GTTGGTTACT TCAAAAAGAG CAAACACTGG 2040
GGATCAAATT ATTTTAAGAG GTATTTCAGT TTTAAATGCA AAATAGCCTT ATTTTCATTT 2100
AGTTTGTTAβ CACTATAGTG AGCTTTTCAA ACACTATTTT AATCTTTATA TTTAACTTAT 2160
AAATTTTCCT TTCT 2174
Seq ID NO: C245 Protein Sequence Protein Accession ff: NP 004433
60
120
Figure imgf001343_0002
180
YGGCMSLIAV RVFYRKCPRI IQNGAIFQET LSGAESTSLV AARGSCIANA EEVDVPIKLY 240
CNGDGEWLVP IGRCMCKAGF EAVENGTVCR GCPSCTFKAN QGDEACTHCP INSRTTSEGA 300
TNCVCRNβYY RADLDPLDMP CTTIPSAPQA VISSVNETSL MLEWTPPRDS GGREDLVYNI 360
ICKSCβSGRβ ACTRCGDNVQ YAPRQLGLTE PRIYISDLLA HTQYTFEIQA VNGVTDQSPF 420
SPQFASVNIT TNQAAPSAVS IMHQVSRTVD SITLSWSQPD QPNGVILDYE LQYYEKELSE 480
YNATAIKSPT NTVTVQGLKA GAIYVFQVRA RTVAGY6RYS GKMYFQTMTE AEYQTSIQEK 540
LPLIIGSSAA GLVFLIAVW IAIVCNRRRG FERADSEYTD KLQHYTSGHM TPGMKIYIDP 600
FTYEDPNEAV REFAKEIDIS CVKIEQVIGA GEFGEVCSGH LKLPGKREIF VAIKTLKSGY 660
TEKQRRDFLS EASIMGQFDH PNVIHLEGW TKSTPVMIIT EFMENGSLDS FLRQNDGQFT 720
VIQLVGMLRG IAAGMKYLAD MNYVHRDLAA RNILVNSNLV CKVSDFGLSR FLEDDTSDPT 780
YTSALGGKIP IRWTAPEAIQ YRKFTSASDV WSYβlVMWEV MSYGERPYWD MTNQDVINAI 840
EQDYRLPPPM DCPSALHQLM LDCWQKDRNH RPKFGQIVNT LDKMIRNPNS LKAMAPLSSG 900
INLPLLDRTI PDYTSFNTVD EWLEAIKMGQ YKESFANAGF TSFDWSQMM MEDILRVGLT 960
LAGHQKKILN SIQVMRAQMN QIQSVEV 987
Seq ID NO: C246 Protein Sequence Protein Accession ft: NP_114148.1
1 11 21 31 41 51
I I I I I I
MDARRVPQKD LRVKKNLKKF RYVKLISMET SSSSDDSCDS FASDNFANTR LQSVREGCRT 60
RSQCRHSGPL RVAMKFPARS TRGATNKKAE SRQPSENSVT DSNSDSEDES GMNFLEKRAL 120
NIKQNKAMLA KLMSELESFP GSFRGRHPLP GSDSQSRRPR RRTFPGVASR RNPERRARPL 180
TRSRSRILGS LDALPMEEEE EEDKYMLVRK RKTVDGYMNE DDLPRSRRSR SSVTLPHIIR 240
PVEEITEGGV GERLQQFSKR RYITVHWALL VINAVRRLLI PKQTAETQTA GAFEASSVAP 300
AFETVMVKRS GMLCWIRTGI ARLVEESATA VSAGSEMDGV RLGSLCI 347
Seq ID NO: C247 Protein Sequence Protein Accession ft: NP_036577.1
1 11 21 31 41 51
I I I I I I
MENPSPAAAL GKALCALLLA TLGAAGQPLG GESICSARAP AKYSITFTGK WSQTAFPKQY 60
PLFRPPAQWS SLLGAAHSSD YSMWRKNQYV SNGLRDFAER GEAWALMKEI EAAGEALQSV 120
HAVFSAPAVP SGTGQTSAEL EVQRRHSLVS FWRIVPSPD WFVGVDSLDL CDGDRWREQA 180
ALDLYPYDAG TDSGFTFSSP NFATIPQDTV TEITSSSPSH PANSFYYPRL KALPPIARVT 240
LVRLRQSPRA FIPPAPVLPS RDNEIVDSAS VPETPLDCEV SLWSSWGLCG GHCGRLGTKS 300
RTRYVRVQPA NNGSPCPELE EEAECVPDNC V 331
Seq ID NO: C248 Protein Sequence Protein Accession #: NP 063947.1
1 11 21 31 41 51
I I I I I I
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIW VLIKVILDKY 60 YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT 120
GNWFSACFDN FTEALAETAC RQMGYΞSKPT FRAVEIGPDQ DLD EITEN SQELRMRNSS 180
GPCLSGSLVS LHCLACGKSL KTPRWGGEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV 240
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL 300
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD 360 AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT 420
KVSAYLNWIY NVWKAEL 437
Seq ID NO: C249 Protein Sequence Protein Accession ft: NP_003036.1
1 11 21 31 41 51 l l l l l !
MGCKVLLNIG QQMLRRKWD CSREETRLSR CLNTFDLVAL GVGSTLGAGV YVLAGAVARE 60
NAGPAIVISF LIAALASVLA GLCYGEFGAR VPKTGSAYLY SYVTVβELWA FITGWNLILS 120
YIIGTSSVAR AWSATFDELI GRPIGEFSRT HMTLNAPGVL AENPDIFAVI IILILTGLLT 180
LGVKESAMVN KIFTCINVLV LGFIMVSGFV KGSVKNWQLT EEDFGNTSGR LCLNNDTKEG 240
KPGVGGFMPF GFSGVLSGAA TCFYAFVGFD CIATTGEEVK NPQKAIPVGI VASLLICFIA 300
YFGVSAALTL MMPYFCLDNN SPLPDAFKHV GWEGAKYAVA VGSLCALSAS LLGSMFPMPR 360
VIYAMAEDGL LFKFLANVND RTKTPIIATL ASGAVAAVMA FLFDLKDLVD LMSIGTLLAY 420
SLVAACVLVL RYQPEQPNLV YQMASTSDEL DPADQNELAS TNDSQLGFLP EAEMFSLKTI 480
LSPKNMEPSK ISGLIVNIST SLIAVLIITF CIVTVLGREA LTKGALWAVF LLAGSALLCA 540
WTGVIWRQP ESKTKLSFKV PFLPVLPILS IFVNVYLMMQ LDQβTWVRFA VWMLIGFIIY 600
FGYGLWHSEE ASLDADQART PDGNLDQCK 629
Seq ID NO: C250 Protein Sequence Protein Accession #: NP.002767.1
1 11 21 31 41 51
I I I I I I
MRAPHLHLSA ASGARALAKL LPLLMAQLWA AEAALLPQND TRLDPEAYGA PCARGSQPWQ 60
VSLFNGLSFH CAGVLVDQSW VLTAAHCGNK PLWARVGDDH LLLLQGEQLR RTTRSWHPK 120
YHQGSGPILP RRTDEHDLML LKLARPWPG PRVRALQLPY RCAQPGDQCQ VAGWGTTAAR 180
RVKYNKGLTC SSITILSPKE CEVFYPG T NNMICAGLDR GQDPCQSDSG GPLVCDETLQ 240
GILSWGVYPC GSAQHPAVYT QICKYMSWIN KVIRSN 276
Seq ID NO: C251 Protein Sequence Protein Accession if: XP 095088.3 1 11 21 31 41 51 i i i i i i
MTRAATAEPG RVSPASPARS TAGLPRAFLQ SLRTLLDILD DWQRGCVHLR EIQSLWVEAR 60
ELPSGVLEGL SQRRGPQPGA AVRSRRGGAV PRGARAVPER CAGTETRRGR RCSGLQRLGG 120
GFRGCPADPC ARGEHRRHTI TSGVDCGLLK QMKELEQEKE VLLQGLEMMA QGRDWYQQQL 180
QQVQERQCRL GQSRASADFG AVGSPRPLGR LLPKVQEVAR WLGELLAEAC AGRALPTSSS 240
GPPCSALTST SSPGWQQQII LMLKEQNRLL TQEVTEKSER ITQLEQKSAL IKQLFEARAL 300
SQQDGGLSPA GPHIEPLTRF RLPVLTWAGA LLSPHSPQLL LPLSADSGGP LHELPDTWFP 360
AVLLWVPSPG KRTAHARLHF HQRPAEGAWQ LGCGAEAAPE TCGTLPHFES HKTTCEPDSL 420
GGPCPQEGDR SWSHLGAAFD VAPAVAKVTP NREDAAGSRH GDICPLCPKG LLTFRDIAIE 480
FSLAEWQCLD HAQQNLYRDV MLENYRNLFS L6MTVSKPDL IACLEQNKEP QNIKRNEMAA 540
KHPVTCSHFN QDLQPEQSIK DSLQKVIPRT YGKCGHENLQ LKKCCKRVDE CEVHKGGYND 600
LNQCLSNTQN KIFQTHKCVK VFSKFSNSNR HNARYTGKKH LKCKKYGKSF CMFSHLNQHQ 660
IIHTKEKSYK CEECGKSFNH SSSGTTHKRI LTGEKPYRCE ECGKAFRWPS NLTRHKRIHT 720
GEKPYACEEC CQAFRRSSTL TNHKRIHTGE RPYKCEECGK AFSVSSALIY HKRIHTGEKP 780
YTCEECGKAF NCSSTLKTHK IIHTGEKPYT CEECGRTFNC SSTVKAHKRI HTGEKPYKCE 840 ECDKAFKWHS SLAKHKIIHT CEKPYKCSDS KALAKSSEVQ KVYSβDGENG IRVHKKKETQ 900
GWLVRNKNEN RTGLFQIRAA VRPNRDPSWG QQEGSLTDPI QRKEEPDLQN HYDHQNALED 960
QRNTGVGGLL TFRDWIEFS LEEWQCLDHA QQNLYRDVML ENYRNLVSLG IAVSKPDLIT 1020
CLEQNKEPWN IKRNEMVTKH PDLPPELGIK DSLQKVIPRR YGKSGHDNLQ VKTCKSMGEC 1080
EVQKGβCNEV NQCLSTTQNK IFQTHKCVKV FβKFSNSNRH KTRHTGKKHF KCKKYGKSFC 1140
MVSQLHQHQI IHTRENSYQC EECGKPFNCS STLSKHKRIH TβEKPYRCEE CGKAFTWSST 1200
LTKHRRIHTβ EKPYTCEECG QAFSRSSTLA NHKRIHTGEK PYTCEECβKA FSLSSSLTYH 1260
KRIHTGEKPY TCEECGKAFN CSSTLKKHKI IHTGEKPYKC KECGKAFAFS STLNTHKRIH 1320
TGEEPYKCEE CDKAFKWSSS LANHKSMHTG EKPYKCE 1357
10
Seq ID NO: C252 Protein Sequence Protein Accession ft: NP 114433.1
, _ 1 11 21 31 41 51
15 i i i i i i
MASRSMRLLL LLSCLAKTβV LβDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS 60 YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG 120 KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP 158
20 Seq ID NO: C253 Protein Sequence Protein Accession ft: XP.051860.2
1 11 21 31 41 51
1 I I I I I
25 MDGVNLSTEV VYKKGQDYRF ACYDRGRACR SYRVRFLCβK PVRPKLTVTI DTNVNSTILN 60
LEDNVQSWKP GDTLVIASTD YSMYQAEEFQ VLPCRSCAPN QVKVAGKPMY LHIGEEIDGV 120
DMRAEVGLLS RNIIVMGEME DKCYPYRNHI CNFFDFDTFG GHIKFALGFK AAHLEGTELK 180
HMGQQLVGQY PIHFHLAGDV DERGGYDPPT YIRDLSIHHT FSRCVTVHGS NGLLIKDWG 240
YNSLGHCFFT EDGPEERNTF DHCLGLLVKS GTLLPSDRDS KMCKMITGDS YPGYIPKPRQ 300
30 DCNAVSTFWM ANPNNNLINC AAAGSEETGF WFIFHHVPTG PSVGMYSPGY SEHIPLGKFY 360
NNRAHSNYRA GMIIDNGVKT TEASAKDKRP FLSIISARYS PHQDADPLKP REPAIIRHFI 420
AYKNQDHGAW LRGGDVWLDS CRFADNGIGL TLASGGTFPY DDGSKQEIKN SLFVGESGNV 480
GTEMMDNRIW βPGGLDHSGR TLPIGQNFPI RGIQLYDGPI NIQNCTFRKF VALEGRHTSA 540
LAFRLNNAWQ SCPHNNVTGI AFEDVPITSR VFFGEPGPWF NQLDMDGDKT SVFHDVDGSV 600
35 SEYPGSYLTK NDNWLVRHPD CINVPDWRGA ICSGCYAQMY IQAYKTSNLR MKIIKNDFPS 660
HPLYLEGALT RSTHYQQYQP WTLQKGYTI HWDQTAPAEL AIWLINFNKG DWIRVGLCYP 720
RGTTFSILSD VHNRLLKQTS KTGVFVRTLQ MDKVEQSYPG RSHYYWDEDS GLLFLKLKAQ 780
NEREKFAFCS MKGCERIKIK ALIPKNAGVS DCTATAYPKF TERAWDVPM PKKLFGSQLK 840
TKDHFLEVKM ESSKQHFFHL WNDFAYIEVD GKKYPSSEDG IQVWIDGNQ βRWSHTSFR 900
40 NSILQGIPWQ LFNYVATIPD NSIVLMASKG RYVSRGPWTR VLEKLGADRG LKLKEQMAFV 960
GFKGSFRPIW VTLDTEDHKA KIFQWPIPV VKKKKL 996
Seq ID NO: C254 Protein Sequence Protein Accession ft: NP_055188.1
45
1 11 21 31 41 51
I I I I I I
MTALSSENCS FQYQLRQTNQ PLDVNYLLFL IILGKILLNI LTLGMRRKNT CQNFMEYFCI 60
SLAFVDLLLL VNISIILYFR DFVLLSIRFT KYHICLFTQI ISFTYGFLHY PVFLTACIDY 120
50 CLNFSKTTKL SFKCQKLFYF FTVILIWISV LAYVLGDPAI YQSLKAQNAY SRHCPFYVSI 180
QSYWLSFFMV MILFVAFITC WEEVTTLVQA IRITSYMNET ILYFPFSSHS SYTVRSKKIF 240
LSKLIVCFLS TWLPFVLLQV IIVLLKVQIP AYIEMNIPWL YFVNSFLIAT VYWFNCHKLN 300
LKDIGLPLDP FVNWKCCFIP LTIPNLEQIE KPISIMIC 338
55 Seq ID NO: C255 Protein Sequence Protein Accession # : Eos sequence
1 11 21 31 41 51
60 I I I I I I
MALVLGSLLL LGLCGNSFSG GQPSSTDAPK AWNYELPATN YETQDSHKAG PIGILFELVH 60
IFLYWQPRD FPEDTLRKFL QKAYESKIDY DKIVYYEAβl ILCCVLGLLF IILMPLVGYF 120
FCMCRCCNKC GGEMHQRQKE NGPFLRKCFA ISLLVICIII SIGIFYGFVA NHQVRTRIKR 180
SRKLADSNFK DLRTLLNETP EQIKYILAQY NTTKDKAFTD LNSINSVLGG GILDRLRPNI 240
IPVLDEIKSM ATAIKETKEA LENMNSTLKS LHQQSTQLΞS SLTSVKTSLR SSLNDPLCLV 300
65 HPSSETCNSI RLSLSQLNSN PELRQLPPVD AELDNVNNVL RTDLDGLVQQ GYQSLNDIPD 360
RVQRQTTTW AGIKRVLNSI GSDIDNVTQR LPIQDILSAF SVYVNNTESY IHRNLPTLEE 420
YDSYWWLGGL VICSLLTLIV IFYYLGLLCG VCGYDRHATP TTRGCVSNTG GVFLMVGVGL 480
SFLFCWILMI IWLTFVFGA NVEKLICEPY TSKELFRVLD TPYLLNEDWE YYLSGKLFNK 540
SKMKLTFEQV YSDCKKNRGT YGTLHLQNSF NISEHLNINE HTGSISSELE SLKVNLNIFL 600
70 LGAAGRKNLQ DFAACGIDRM NYDSYLAQTG KSPAGVNLLS FAYDLEAKAN SLPPGNLRNS 660
LKRDAQTIKT IHQQRVLPIE QSLSTLYQSV KILQRTGNGL LERVTRILAS LDFAQNFITN 720
NTSSVIIEET KKYGRTIIGY FEHYLQWIEF SISEKVASCK PVATALDTAV DVFLCSYIID 780
PLNLFWFGIG KATVFLLPAL IFAVKLAKYY RRMDSEDVYD DVETIPMKNM ENGNNGYHKD 840
HVYGIHNPVM TSPSQH 856
75
Seq ID NO: C256 Protein Sequence Protein Accession ff : NP_149038.1
1 11 21 31 41 51
80 1 I I I I I
MKAIIHLTLL ALLSVNTATN QGNSADAVTT TETATSGPTV AAADTTETNF PETASTTANT 60
PSFPTATSPA PPIISTHSSS TIPTPAPPII STHSSSTIPI PTAADSESTT NVNSLATSDI 120
ITASSPNDGL ITMVPSETQS NNEMSPTTED NQSSGPPTGT ALLETSTLNS TGPSNPCQDD 180
PCADNSLCVK LHNTSFCLCL EGYYYNSSTC KKGKVFPGKI SVTVSETFDP EEKHSMAYQD 240 LHSEITSLFK DVFGTSVYGQ TVILTVSTSL SPRSEMRADD KFVNVTIVTI LAETTSDNEK 300
TVTEKINKAI RSSSSNFLNY DLTLRCDYYG CNQTADDCLN GLACDCKSDL QRPNPQSPFC 360
VASSLKCPDA CNAQHKQCLI KKSGGAPECA CVPβYQEDAN βNCQKCAFGY SGLDCKDKFQ 420
LILTIVGTIA GIVILSMIIA LIVTARSNNK TKHIEEENLI DEDFQNLKLR STGFTNLGAE 480
GSVFPKVRIT ASRDSQMQNP YSRHSSMPRP DY 512
Seq ID NO: C257 Protein Sequence Protein Accession ft: NP_001423.1
1 11 21 31 41 51
I I I I I I
MTAGRRMEML CAGRVPALLL CLGFHLLQAV LSTTVIPSCI PGESSDNCTA LVQTEDNPRV 60
AQVSITKCSS DMNGYCLHGQ CIYLVDMSQN YCRCEVGYTG VRCEHFFLTV HQPLSKEYVA 120
LTVILIILFL ITWGSTYYF CRWYRNRKSK EPKKEYERVT SGDPELPQV 169
Seq ID NO: C258 Protein Sequence Protein Accession #: AAC63902.1
1 11 21 31 41 51 i i i i i i
MDRSKENCIS GPVKATAPVG GPKRVLVTQQ IPCQNPLPVN SGQAQRVLCP SNSSQRVPLQ 60
AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN 120
EESKKRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA LKVLFKAQLE KAGVEHQLRR 180
EVEIQSHLRH PNILRLYGYF HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL 240 ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM 300
IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ANTYQETYKR ISRVEFTFPD FVTEGARDLI 360
SRLLKHNPSQ RPMLREVLEH PWITANSSKP SNCQNKESAS KQS 403
Seq ID NO: C259 Protein Sequence Protein Accession ft: NP_037504.1
1 11 21 31 41 51
I I I I I I
MSRTAYTVGA LLLLLGTLLP AAEGKKKGSQ GAIPPPDKAQ HNDSEQTQSP QQPβSRNRGR 60 GQβRGTAMPG EEVLESSQEA LHVTERKYLK RDWCKTQPLK QTIHEEGCNS RTIINRFCYG 120
QCNSFYIPRH IRKEEGSFQS CSFCKPKKFT TMMVTLNCPE LQPPTKKKRV TRVKQCRCIS 180
IDLD 184
Seq ID NO: C260 Protein Sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MKVGVLWLIS FFTFTDGHGG FLGKNDGIKT KKELIVNKKK HLGPVEEYQL LLQVTYRDSK 60
EKRDLRNFLK LLKPPLLWSH GLIRIIRAKA TTDCNSLNGV LQCTCEDSYT WFPPSCLDPQ 120
NCYLHTAGAL PSCECHLNNL SQSVNFCERT KIWGTFKINE RFTNDLLNSS SAIYSKYANG 180
IEIQLKKAYE RIQGFESVQV TQFRNGSIVA GYEWGSSSA SELLSAIEHV AEKAKTALHK 240
LFPLEDGSFR VFGKAQCNDI VFGFGSKDDE YTLPCSSGYR GNITAKCESS GWQVIRETCV 300
LSLLEELNKN FSMIVGNATE AAVSSFVQNL SVIIRQNPST TVGNLASWS ILSNISSLSL 360
ASHFRVSNST MEDVISIADN ILNSASVTNW TVLLREEKYA SSRLLETLEN ISTLVPPTAL 420
PLNFSRKFID WKGIPVNKSQ LKRGYSYQIK MCPQNTSIPI RGRVLIGSDQ FQRSLPETII 480
SMASLTLGNI LPVSKNGNAQ VNGPVISTVI QNYSINEVFL FFSKIESNLS QPHCVFWDFS 540
HLQWNDAGCH LVNETQDIVT CQCTHLTSFS ILMSPFVPST IFPWKWITY VGLGISIGSL 600
ILCLIIEALF WKQIKKSQTS HTRRICMVNI ALSLLIADVW FIVGATVDTT VNPSGVCTAA 660 VFFTHFFYLS LFFWMLMLGI LLAYRIILVF HHMAQHLMMA VGFCLGYGCP LIISVITIAV 720
TQPSNTYKRK DVCWLNWSNG SKPLLAFWP ALAIVAVNFV WLLVLTKLW RPTVGERLSR 780
DDKATIIRVG KSLLILTPLL GLTWGFGIGT IVDSQNLAWH VIFALLNAFQ GFFILCFGIL 840
LDSKLRQLLF NKLSALSSWK QTEKQNSSDL SAKPKFSKPF NPLQNKGHYA FSHTGDSSDN 900
IMLTQFVSNE 910
Seq ID NO: C261 Protein Sequence Protein Accession ft: NP 000575.1
1 11 21 31 41 51 i i i i i i
MTSKLAVALL AAFLISAALC EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH 60
CANTEIIVKL SDGRELCLDP KENWVQRWE KFLKRAENS 99
Seq ID NO: C262 Protein Sequence Protein Accession ft: NP_005594.1
1 11 21 31 41 51
I I I I I I
MSTERDSETT FDEDSQPNDE WPYSDDETE DELDDQGSAV EPEQNRVNRE AEENREPFRK 60
ECTWQVKAND RKYHEQPHFM NTKFLCIKES KYANNAIKTY KYNAFTFIPM NLFEQFKRAA 120
NLYFLALLIL QAVPQISTLA WYTTLVPLLV VLGVTAIKDL VDDVARHKMD KEINNRTCEV 180
IKDGRFKVAK WKEIQVGDVI RLKKNDFVPA DILLLSSSEP NSLCYVETAE LDGETNLKFK 240
MSLEITDQYL QREDTLATFD GFIECEEPNN RLDKFTGTLF WRNTSFPLDA DKILLRGCVI 300
RNTDFCHGLV IFAGADTKIM KNSGKTRFKR TKIDYLMNYM VYTIFWLIL LSAGLATCHA 360
YWEAQVGNSS WYLYDGEDDT PSYRGFLIFW 6YIIVLNTMV PISLYVSVEV IRLGQSHFIN 420
WDLQMYYAEK DTPAKARTTT LNEQLGQIHY IFSDKTGTLT QNIMTFKKCC INGQIYGDHR 480
DASQHNHNKI EQVDFSWNTY ADGKLAFYDH YLIEQIQSGK EPEVRQFFFL LAVCHTVMVD 540
RTDGQLNYQA ASPDEGALVN AARNFGFAFL ARTQNTITIS ELGTERTYNV LAILDFNSDR 600
KRMSIIVRTP EGNIKLYCKG ADTVIYERLH RMNPTKQETQ DALDIFANET LRTLCLCYKE 660 IEEKEFTEWN KKFMAASVAS TNRDEALDKV YEEIEKDLIL LGATAIEDKL QDGVPETISK 720
LAKADIKIWV LTGDKKETAE NIGFACELLT EDTTICYGED INSLLHARME NQRNRGGVYA 780
KFAPPVQESF FPPGGNRALI ITGSWLNEIL LEKKTKRNKI LKLKFPRTEE ERRMRTQSKR 840
RLEAKKEQRQ KNFVDLACEC SAVICCRVTP KQKAMWDLV KRYKKAITLA IGDGANDVNM 900
IKTAHIGVGI SGQEGMQAVM SSDYSFAQFR YLQRLLLVHG RWSYIRMCKF LRYFFYKNFA 960
FTLVHFWYSF FNGYSAQTAY EDWFITLYNV LYTSLPVLLM βLLDQDVSDK LSLRFPβLYI 1020
VGQRDLLFNY KRFFVSLLHG VLTSMILFFI PLGAYLQTVG QDGEAPSDYQ SFAVTIASAL 1080
VITVNFQIGL DTSYWTFVNA FSIFGSIALY FGIMFDFHSA GIHVLFPSAF QFTGTASNAL 1140
RQPYIWLTII LTVAVCLLPV VAIRFLSMTI WPSESDKIQK HRKRLKAEEQ WQRRQQVFRR 1200 βVSTRRSAYA FSHQRGYADL ISSGRSIRKK RSPLDAIVAD GTAEYRRTGD S 1251
Seq ID NO: C263 Protein Sequence Protein Accession tf: XM_044533
1 11 21 31 41 51
I I I I I I
MLRTAMβLRS WLAAPWGALP PRPPLLLLLL LLLLLQPPPP TWALSPRISL PLGSEERPFL 60
RFEAEHISNY TALLLSRDGR TLYVGAREAL FALSSNLSFL PGGEYQELLW GADAEKKQQC 120
SFKGKDPQRD CQNYIKILLP LSGSHLFTCG TAAFSPMCTY INMENFTLAR DEKGNVLLED 180
GKGRCPFDPN FKSTAL DG ELYTGTVSSF QGNDPAISRS QSLRPTKTES SLNWLQDPAF 240
VASAYIPESL GSLQGDDDKI YFFFSETGQE FEFFENTIVS RIARICKGDE GGERVLQQRW 300
TSFLKAQLLC SRPDDGFPFN VLQDVFTLSP SPQDWRDTLF YGVFTSQWHR βTTEβSAVCV 360
FTMKDVQRVF SGLYKEVNRE TQQWYTVTHP VPTPRPGACI TNSARERKIN SSLQLPDRVL 420
NFLKDHFLMD GQVRSRMLLL QPQARYQRVA VHRVPGLHHT YDVLFLGTGD GRLHKAVSVG 480
PRVHIIEELQ IFSSGQPVQN LLLDTHRGLL YAASHSGWQ VPMANCSLYR SCGDCLLARD 540
PYCAWSGSSC KHVSLYQPQL ATRPWIQDIE GASAKDLCSA SSWSPSFVP TGEKPCEQVQ 600
FQPNTVNTLA CPLLSNLATR LWLRNGAPVN ASASCHVLPT GDLLLVGTQQ LGEFQCWSLE 660
EGFQQLVASY CPEWEDGVA DQTDEGGSVP VIISTSRVSA PAGGKASWGA DRSYWKEFLV 720
MCTLFVLAVL LPVLFLLYRH RNSMKVFLKQ GECASVHPKT CPWLPPETR PLNGLGPPST 780
PLDHRGYQSL SDSPPGSRVF TESEKRPLSI QDSFVEVSPV CPRPRVRLGS EIRDSW 837
Seq ID NO: C264 Protein Sequence Protein Accession #: NP_008950.1
1 11 21 31 41 51
I I I I I I
MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKβl SAFPESDNLF 60
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE 120
KWSALYDVRT ILLSIQSLLG EPNIDSPLNT HAAELWKNPT AFKKYLQETY SKQVTSQEP 179
Seq ID NO: C265 Protein Sequence -Protein Accession ft: NP 055399.1 1 11 21 31 41 51 i i i i i i
MGRGWGFLFG LLGAVWLLSS GHGEEQPPET AAQRCFCQVS GYLDDCTCDV ETIDRFNNYR 60
LFPRLQKLLE SDYFRYYKVN LKRPCPFWND ISQCGRRDCA VKPCQSDEVP DGIKSASYKY 120
SEEANNLIEE CEQAERLGAV DESLSEETQK AVLQWTKHDD SSDNFCEADD IQSPEAEYVD 180
LLLNPERYTG YKGPDAWKIW NVIYEENCFK PQTIKRPLNP LASGQGTSEE NTFYSWLEGL 240
CVEKRAFYRL ISGLHASINV HLSARYLLQE TWLEKKWGHN ITEFQQRFDG ILTEGEGPRR 300
LKNLYFLYLI ELRALSKVLP FFERPDFQLF TGNKIQDEEN KMLLLEILHE IKSFPLHFDE 360
NSFFAGDKKE AHKLKEDFRL HFRNISRIMD CVGCFKCRLW GKLQTQGLGT ALKILFSEKL 420
IANMPESGPS YEFHLTRQEI VSLFNAFGRI STSVKELENF RNLLQNIH 468
Seq ID NO: C266 Protein Sequence Protein Accession ft: NP_002879.1
1 11 21 31 41 51
I I I I I I
MQPRRQRLPA PWSGPRGPRP TAPLLALLLL LAPVAAPAGS GGPDDPGQPQ DAGVPRRLLQ 60
QKARAALHFF NFRSGSPSAL RVLAEVQEGR A INPKEGCK VHWFSTERY NPESLLQEGE 120
GRLGKCSARV FFKNQKPRPT INVTCTRLIE KKKRQQEDYL LYKQMKQLKN PLEIVSIPDN 180
HGHIDPSLRL IWDLAFLGSS YVMWEMTTQV SHYYLAQLTS VRQWVRKT 228
Seq ID NO: C267 Protein Sequence Protein Accession #-. NP_005400.1
1 11 21 31 41 51
I I I I I I
MSVKGMAIAL AVILCATWQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI 60
EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF 94
Seq ID NO: C268 Protein Sequence Protein Accession ff: FGENESH predicted
1 11 21 31 41 51 l l l l l !
MLRQVLRRGL QSFCHRLGLC VSRHPVFFLT VPAVLTITFG LSALNRFQPE GDLERLVAPS 60
HSLAKIERSL ASSLFPLDQS KSQLYSDLHT PGRYGRVILL SPTGDNILLQ AEGILQTHRA 120
VLEMKVNHKG YNYTFSHLCV LRNQDKKCVL DDIISVLEDL RQAAVSNKTT ARVQVRYPNT 180
KLKVCSFCML LPIKEAALHF LP 202
Seq ID NO: C269 Protein Sequence Protein Accession ft: NP_002429.1 11 21 31 41 51
I I I I I
MRLPLLLVFA SVIPβAVLLL DTRQFLIYNE DHKRCVDAVS PSAVQTAACN QDAESQKFRW 60 VSESQIMSVA FKLCLGVPSK TDWVAITLYA CDSKSEFQKW ECKNDTLLGI KβEDLFFNYG 120 NRQEKNIMLY KGSGLWSRWK lYGTTDNLCS RGYEAMYTLL GNANGATCAF PFKFENKWYA 180 DCTSAGRSDG WLWCGTTTDY DTDKLFGYCP LKFEGSESLW NKDPLTSVSY QINSKSALTW 240 HQARKSCQQQ NAELLSITEI HEQTYLTGLT SSLTSGLWIG LNSLSFNSGW QWSDRSPFRY 300 LNWLPGSPSA EPβKSCVSLN PGKNAKWENL ECVQKLGYIC KKGNTTLNSF VIPSESDVPT 360 HCPSQWWPYA GHCYKIHRDE KKIQRDALTT CRKEGGDLTS IHTIEELDFI ISQLGYEPND 420 ELWIGLNDIK IQMYFEWSDG TPVTFTKWLR GEPSHENNRQ EDCWMKGKD GYWADRGCEW 480 PLGYICKMKS RSQGPEIVEV EKGCRKGWKK HHFYCYMIGH TLSTFAEANQ TCNNENAYLT 540 TIEDRYEQAF LTSFVGLRPE KYFWTGLSDI QTKGTFQWTI EEEVRFTHWN SDMPGRKPGC 600 VAMRTCIAGG LWDVLKCDEK AKFVCKHWAE GVTHPPKPTT TPEPKCPEDW βASSRTSLCF 660 KLYAKGKHEK KTWFESRDFC RALGGDLASI NNKEEQQTIW RLITASGSYH KLFWLβLTYβ 720 SPSEβFTWSD GSPVSYENWA YGEPNNYQNV EYCGELKGDP TMSWNDINCE HLNNWICQIQ 780 KGQTPKPEPT PAPQDNPPVT EDGWVIYKDY QYYFSKEKET MDNARAFCKR NF6DLVSIQS 840 ESEKKFLWKY VNRNDAQSAY FlβLLISLDK KFAWMDGSKV DYVSWATGEP NFANEDENCV 900 TMYSNSGFWN DINCGYPNAF ICQRHNSSIN ATTVMPTMPS VPSGCKEβWN FYSNKCFKIF 960 GFMEEERKNW QEARKACIGF GGNLVSIQNE KEQAFLTYHM KDSTFSAWTG LNDVNSEHTF 1020 LWTDGRGVHY TNWGKGYPGG RRSSLSYEDA DCWIIGGAS NEAGKWMDDT CDSKR6YICQ 1080 TRSDPSLTNP PATIQTDGFV KYGKSSYSLM RQKFQWHEAE TYCKLHNSLI ASILDPYSNA 1140 FAWLQMETSN ERVWIALNSN LTDNQYTWTD KWRVRYTNWA ADEPKLKSAC VYLDLDβYWK 1200 TAHCNESFYF LCKRSDEIPA TEPPQLPGRC PESDHTAWIP FHGHCYYIES SYTRNWGQAS 1260 LECLRMGSSL VSIESAAESS FLSYRVEPLK SKTNFWIGLF RNVE6TWLWI NNSPVSFVNW 1320 NTGDPSGERN DCVALHASSG FWSNIHCSSY KGYICKRPKI IDAKPTHELL TTKADTRKMD 1380 PSKPSSNVAG WIIVILLIL TGAGLAAYFF YKKRRVHLPQ EβAFENTLYF NSQSSPGTSD 1440 MKDLVβNIEQ NEHSVI 1456
Seq ID NO: C270 Protein Sequence Protein Accession ft: Eos sequence
11 21 31 41 51
I I I I I
MVLLHWCLLW LLFPLSSRTQ KLPTRDEELF QMQIRDKAFF HDSSVIPDGA EISSYLFRDT 60 PKRYFFWEE DNTPLSVTVT PCDAPLEWKL SLQELPEDRS GEGSGDLEPL EQQKQQIINE 120 EGTELFSYKG NDVEYFISSS SPSGLYQLDL LSTEKDTHFK VYATTTPESD QPYPELPYDP 180 RVDVTSLGRT TVTLAWKPSP TASLLKQPIQ YCWINKEHN FKSLCAVEAK LSADDAFMMA 240 PKPGLDFSPF DFAHFGFPSD NSGKERSFQA KPSPKLGRHV YSRPKVDIQK ICIGNKNIFT 300 VSDLKPDTQY YFDVFWNIN SNMSTAYVGT FARTKEEAKQ KTVELKDGKI TDVFVKRKGA 360 KFLRFAPVSS HQKVTFFIHS CLDAVQIQVR RDGKLLLSQN VEGIQQFQLR GKPKAKYLVR 420 LKGNKKGASM LKILATTRPT KQSFPSLPED TRIKAFDKLR TCSSATVAWL GTQERNKFCI 480 YKKEVDDNYN EDQKKREQNQ CLGPDIRKKS EKVLCKYFHS QNLQKAVTTE TIKGLQPGKS 540 YLLDVYVIβH GGHSVKYQSK WKTRKFC 568
Seq ID NO: C271 Protein Sequence Protein Accession ft: AAH34229.1
11 21 31 41 51
I I I I I
MEKVQLEFEN QEMEKKLQEF RSTRNKEKED RESSEYYWKS GKVβKLVNQS YMMSQNKGNV 60 VKFSAGKVKL KLLKEQIQEP VKPTVNYKMA NSSECEKPKI NβKVCβQCEN KAALLVCLEC 120 GEDYCSGCFA NVHQKGALKL HRTTLLQARS QILFNVLDVA HQFIKDVNPD EPKEENNSTK 180 ETSKIQHKPK SVLLQRSSSE VEITTMKRAQ RTKPRKSLLC E6SFDEEASA QSFQEVLSQW 240 RTGNHDDNKK QNLHAAVKDS LEECEVQTNL KIWREPLNIE LKEDILSYME KLWLKKHRRT 300 PQEQLFKCYQ IRSHIHMKPL VMHSVLKMKT MKIVMVRRPK YNTQLFYCQ 349
Seq ID NO: C272 Protein Sequence Protein Accession ff: NP 078963.1
11 21 31 41 51
I I I I
MEKLWLKKHR RTPQEQLFKM LSDTFPHPHE T 1TGDAQCSQN ENDEDSDGEE TKVQHTALLL 60 PVETLNIERP EPSLKIVELD DTYEEEFEEA ENIVPYKVKL ADADSQRSCA FHDCQKNSFP 120 YENGIHQHHV FDKGKRDFLN LCLRNSSTYY KDNSKGETSN TDFDNIVDPD VYSSDIEKIE 180 ESTSFERNLK EKNIGLESNQ KSDDSCVSLE SKDTLLGRDL EKAPIEEKLS QDIKESLELS 240 NLYKRPSFEE SKTTKSSLLL QEIACRSKPI TKQYQGLERF FIFDTNERLN LLPSHRLECN 300 NSSTRITLAE DREWIPDHSL SEYADNAIVL GVLQGAQSPS SSRKQQKMGQ KSQRPSTANF 360 PLSNSVKESS SCLSSSHPRS RSAAAQSSSR AASEISEIEY IDITDQNELS LDDTTDQHTL 420 DNLEKELQVL RSLADTSEKL YSLTSEEFPD FSSQSLNISQ ISTDFLKTSH VRGPCGVEEL 480 SCSGRDTKIQ SLLSLSESST DEEEEDFLNK QHVITLPWSK ST 522
Seq ID NO: C273 Protein Sequence Protein Accession #: NP_005399.1
1 11 21 31 41 51
1 I I I I I
MKVSAVLLCL LLMTAAFNPQ GLAQPDALNV PSTCCFTFSS KKISLQRLKS YVITTSRCPQ 60 KAVIFRTKLG KEICADPKEK WVQNYMKHLG RKAHTLKT 98
Seq ID NO: C274 Protein Sequence Protein Accession ft: BAC05158.1
11 51 I I I I I I
MFLLTGGVSL KSAEKNPDPT WLQDKSWEEI CRASEFPAFR GLRQHFCEHI YEWREIYDSK 60
EPHNAKFPAP MDKNLNELQK IIILRCLRPD KITPAITNYV TDKLGKKFVE PPPFDLTKSY 120
LDSNCTIPLI FVLSPGADPM ASLLKFANDK SMSGNKFQAI SLGQGQGPIA AKMIKAAIEE 180
GTWVCLQNCH LAVSWMPMLE KICEDFTSET CNSSFRLWLT SYPSSKFPVT ILQNGVKMTN 240
EPPTGLRLNL LQSYLTDPVS DPEFFKGCRG KELLFINEYD TIPFEAISYL TGECNYGGRV 300
TDDWDRRLLL TMLADFYNLY IVENPHYKFS PSGNYFAPPK GTYEDYIEFI KKLPFTQHPE 360
IFGLHENVDI SKDLQQTKTL FESLLLTQGG SKQTGASGST DQILLEITKD ILNKLPSDFD 420
IEMALRKYPV RYEESMNTVL VQEMERFNNL IITIRNTLRD LEKAIKβV MDSALEALSS 480
SLLVGKVPEI WAKRSYPSLK PLGSYITDFL ARLNFLQDWY NSβKPCVFWL SGFFFTQAFL 540
TGAMQNYARK YTTPIDLLGY EFEVIPSDTS DTSPEDGVYI HGLYLDGARW DRESGLLAEQ 600
YPKLLFDLMP IIWIKPTQKS RIIKSDAYVC PLYKTSERKG TLSTTGHSTN FVIAMLLKTD 660
QPTRHWIKRG VALLCQLDD 679 Seq ID NO: C275 Protein Sequence Protein Accession ff : AAA60212.1
1 11 21 31 41 51 l l l l l !
MAESHLLQWL LLLLPTLCGP GTAAWTTSSL ACAQGPEFWC QSLEQALQCR ALGHCLQEVW 60
GHVGADDLCQ ECEDIVHILN KMAKEAIFQD TMRKFLEQEC NVLPLKLLMP QCNQVLDDYF 120
PLVIDYFQNQ TDSNGICMHL GLCKSRQPEP EQEPGMSDPL PKPLRDPLPD PLLDKLVLPV 180
LPGALQARPG PHTQDLSEQQ FPIPLPYCWL CRALIKRIQA MIPKGALAVA VAQVCRWPL 240
VAGGICQCLA ERYSVILLDT LLGRMLPQLV CRLVLRCSMD DSAGPRSPTG EWLPRDSECH 300
LCMSVTTQAG NSSEQAIPQA MLQACVGSWL DREKCKQFVE QHTPQLLTLV PRGWDAHTTC 360
QALCVCβTMS SPLQCIHSPD L 381
Seq ID NO: C276 Protein Sequence Protein Accession #: NP_631911.1
1 11 21 31 41 51
I 1 I I I I
MLCCGIPALG LLLLLQGSAD GNGIQGFFYP WSCEGDIWDR ESCGβQAAID SPNLCLRLRC 60 CYRNGVCYHQ RPDENVRRKH MWALVWTCSG LLLLSCSICL FWWAKRRDVL HMPGFLAGPC 120 DMSKSVSLLS KHRGTKKTPS TGSVPVALSK ESRDVEGGTE GEGTEEGEET EGEEEED 177
Seq ID NO: C277 Protein Sequence Protein Accession ff: NP_473364.1
1 11 21 31 41 51
I I I I I I
MKLVTIFLLV TISLCSYSAT AFLINKVPLP VDKLAPLPLD NILPFMDPLK LLLKTLGISV 60
EHLVEGLRKC VNELGPEASE AVKKLLEALS HLV 93
Seq ID NO: C278 Protein Sequence Protein Accession tt : FGENESH predicted
1 11 21 31 41 51
I I I I I I
MPLSYAYKNA ETLAGRHTSS WMSRGAYQRR NTRAAGRPEE CTDRNWHAGR TRGIWLGQLE 60
ERCSDVFGVS FFWWVRGLAG SGAKLQTFTP AQEGAPTVQR QAEALLKCRQ SGRPβRGβAE 120
SERARDASML SPLSAAMRNY PTSSTIPPRR SYSPTEIAHK SYSCSLPDMK ISMAESGPSL 180
DSLDILEDGE SGSPFLVTHL YFLGWTTGM EQLDFETGPN IFDLQIYVKD EVGVTDLQVL 240
TVQVTDVNEP PQFQGNLAED HLRADQPHFN AHSHTYVRW ATALARHRLR SSIGSPFLGT 300
FCVWGMQYF LISPPKSFRM SANGTLFSTT ELDFEAGHRS FHLIVEVRDS GGLKASTELQ 360
VNIVNLNDEV PRFTSPTRVY TVLEELSPGT IVANITAEDP DDEGFPSHLL YSITTVSKYF 420
MINQLTGTIQ VAQRIDRDAG ELRQNPTISL EVLVKDRPYG GQENRIQITF IVEDVNDNPA 480
TCQKFTFRSS LHPALCSKTL TWMDTVLDCF HAADKDIPVT GRFTKERGLI GLTVPHGWGS 540
LTIMAEGKEE QVTSYMDGSR QRDRACVGKL LLIKPSDLMR LSHYHENNSG KTCPHDSISS 600
YQVPPTTCRN SRIQATNNED TSSVTVTVNI LEENDEKPIC TPNSYFLALP VDLKVGTNIQ 660
NFKLTCTDLD SSPRSFRYSI GPGNVNNHFT FSPNAGSNVT RLLLTSRFDY AGGFDKIWDY 720
KLLVYVTDDN LMSDRKKAEA LVETGTVTLS IKVIPHPTTI ITTTPRPRVT YQVLRKNVYS 780
PSAWYVPFVI TLGSILLLGL LVYLWLLAK AIHRHCPCKT GKNKEPLTKK GETKTAERDV 840
WETIQMNTI FDβEAIDPEP EQASLELYAL LPSCCDPSPV TLRKVQVCβE SEETGQCSβH 900
ITLPGKIPVD DPRKQETGLQ GDFEVWTLCP AVKVWGSPQ AERCIRLALS LKKYSSD 957
Seq ID NO: C279 Protein Sequence Protein Accession #: XP L68571.1
1 11 21 31 41 51
I I I I I I
MINQLTGTIQ VAQRIDRDAG ELRQNPTISL EVLVKDRPYG GQENRIQITF IVEDVNDNPA 60
TCQKFTFSIM VPERTAKGTL LLDLNKFCFD DDSEAPNNRF NFTMPSGVGS GSRFLQDPAG 120
SGKIVLIGDL DYENPSNLAA GNKYTVIIQV QDVAPPYYKN NVYVYILTSP ENEFPLIFDR 180
PSYVFDVSER RPAQGHLSGP EEKRLLSICM VRAVCHHFGL HIASGSPRVP GRPIGQSHPQ 240
TLPLQDWEEQ GTSDKERRNE DCRERRRGGN YPDEHYL 277
Seq ID NO: C280 Protein Sequence Protein Accession ft: NP_005257.2
1 11 21 31 41 51
I I I I I I
MGDWSFLGNF LEEVHKHSTV VGKVWLTVLF IFRMLVLGTA AESSWGDEQA DFRCDTIQPG 60
CQNVCYDQAF PISHIRYWVL QIIFVSTPSL VYMGHAMHTV RMQEKRKLRE AERAKEVRGS 120 GSYEYPVAEK AELSCWEEGN GRIALQGTLL NTYVCSILIR TTMEVGFIVG QYFIYGIFLT 180
TLHVCRRSPC PHPVNCYVSR PTEKNVFIVF MLAVAALSLL LSLAELYHLG WKKIRQRFVK 240
PRQHMAKCQL SGPSVGIVQS CTPPPDFNQC LENGPGGKFF NPFSNNMASQ QNTDNLVTEQ 300
VRGQEQTPGE GFIQVRYGQK PEVPNGVSPG HRLPHGYHSD KRRLSKASSK ARSDDLSV 358
Seq ID NO: C281 Protein Sequence Protein Accession # : NP_055274 .2 1 11 21 31 41 51 I 1 I I I I
MYLSICCCFL LWAPALTLKN LNYSVPEEQG AGTVIGNIβR DARLQPGLPP AERGGGGRSK 60
SGSYRVLENS APHLLDVDAD SβLLYTKQRI DRESLCRHNA KCQLSLEVFA NDKEICMIKV 120
EIQDINDNAP SFSSDQIEMD ISENAAP6TR FPLTSAHDPD AβENGLRTYL LTRDDHGLFG 180
LDVKSRGDGT KFPELVIQKA 'LDREQQNHHT LVLTALDGGE PPRSATVQIN VKVIDSNDNS 240 PVFEAPSYLV ELPENAPLβT WIDLNATDA DEGPNGEVLY SFSSYVPDRV RELFSIDPKT 300
GLIRVKβNLD YEENβMLEID VQARDLβPNP IPAHCKVTVK LIDRNDNAPS IβFVSVRQGA 360
LSEAAPPGTV IALVRVTDRD SβKNβQLQCR VLGGGGTGGG GGLGGPGGSV PFKLEENYDN 420
FYTWTDRPL DRETQDEYNV TIVARDGGSP PLNSTKSFAI KILDENDNPP RFTKGLYVLQ 480
VHENNIPGEY LGSVLAQDPD LGQNGTVSYS ILPSHIGDVS IYTYVSVNPT NGAIYALRSF 540 NFEQTKAFEF KVLAKDSGAP AHLESNATVR VTVLDVNDNA PVIVLPTLQN DTAELQVPRN 600
AGLGYLVSTV RALDSDFGES GRLTYEIVDG NDDHLFEIDP SSGEIRTLHP FWEDVTPWE 660
LWKVTDHGK PTLSAVAKLI IRSVSβSLPE GVPRVNGEQH HWDMSLPLIV TLSTISIILL 720
AAMITIAVKC KRENKEIRTY NCRIAEYSHP QLGGGKGKKK KINKNDIMLV QSEVEERNAM 780
NVMNWSSPS LATSPMYFDY QTRLPLSSPR SEVMYLKPAS NNLTVPQGHA GCHTSFTGQG 840 TNASETPATR MSIIQTDNFP AEPNYMGSRQ QFVQSISVAP RLRTQKEPA 889
Seq ID NO: C282 Protein Sequence Protein Accession #: NP 005592.1
1 11 21 31 41 51
I I I I I I
MELCRSLALL GGSLGLMFCL IALSTDFWFE AVGPTHSAHS GLWPTGHGDI ISGYIHVTQT 60 FSIMAVLWAL VSVSFLVLSC FPSLFPPGHG PLVSTTAAFA AAISMWAMA VYTSERWDQP 120 PHPQIQTFFS WSFYLβWVSA ILLLCTβALS LGAHCGGPRP GYETL 165
Seq ID NO: C283 Protein Sequence Protein Accession ft: NP 006424.2
1 11 21 31 41 51 i i i i i i
MATWALLLLA AMLLGNPGLV FSRLSPEYYD LARAHLRDEE KSCPCLAQEG PQGDLLTKTQ 60
ELGRDYRTCL TIVQKLKKMV DKPTQRSVSN AATRVCRTGR SRWRDVCRNF MRRYQSRVTQ 120 GLVAGETAQQ ICEDLRLCIP STGPL 145
Seq ID NO: C284 Protein Sequence Protein Accession ft: NP_005594.1
1 11 21 31 41 51
M IKVSAAALAV IILIATALCAP AISASPYSSDT TIPCCFAYIAR PILPRAHIKEY FIYTSGKCSNP 60
AWFVTRKNR QVCANPEKKW VREYINSLEM S 91
Seq ID NO: C285 Protein Sequence Protein Accession #: NP 071437.1
1 11 21 31 41 51
I I I I I I
MAPβRAVAGL LLLAAAGLGG VAEGPGLAFS EDVLSVFGAN LSLSAAQLQH LLEQMGAASR 60
VGVPEPGQLH FNQCLTAEEI FSLHGFSNAT QITSSKFSVI CPAVLQQLNF HPCEDRPKHK 120
TRPSHSEVWβ YGFLSVTIIN LASLLGLILT PLIKKSYFPK ILTFFVGLAI GTLFSNAIFQ 180
LIPEAFGFDP KVDSYVEKAV AVFGGFYLLF FFERMLKMLL KTYGQNGHTH FGNDNFGPQE 240
KTHQPKALPA INGVTCYANP AVTEANGHIH FDNVS SLQ DGKKEPSSCT CLKGPKLSEI 300
CTIAWMITLC DALHNFIDβL AIGASCTLSL LQGLSTSIAI LCEEFPHELG DFVILLNAGM 360
STRQALLFNF LSACSCYVGL AFGILVGNNF APNIIFALAG GMFLYISLAD MFPEMNDMLR 420
EKVTGRKTDF TFFMIQNAGM LTGFTAILLI TLYAGEIELE 460
Seq ID NO: C286 Protein Sequence Protein Accession ft: NP_004175.1
1 11 21 31 41 51
I I I I I I
MPNSEPASLL ELFNSIATQG ELVRSLKAGN ASKDEIDSAV KMLVSLKMSY KAAAGEDYKA 60
DCPPGNPAPT SNHGPDATEA EEDFVDPWTV QTSSAKGIDY DKLIVRFGSS KIDKELINRI 120
ERATβQRPHH FLRRβlFFSH RDMNQVLDAY ENKKPFYLYT GR6PSSEAMH VβHLIPFIFT 180
KWLQDVFNVP LVIQMTDDEK YLWKDLTLDQ AYGDAVENAK DIIACGFDIN KTFIFSDLDY 240
MGMSSGFYKN WKIQKHVTF NQVKGIFGFT DSDCIGKISF PAIQAAPSFS NSFPQIFRDR 300
TDIQCLIPCA IDQDPYFRMT RDVAPRIGYP KPALLHSTFF PALQGAQTKM SASDPNSSIF 360
LTDTAKQIKT KVNKHAFSGG RDTIEEHRQF GGNCDVDVSF MYLTFFLEDD DKLEQIRKDY 420
TSGAMLTGEL KKALIEVLQP LIAEHQARRK EVTDEIVKEF MTPRKLSFDF Q 471
Seq ID NO: C287 Protein Sequence Protein Accession ft: NP_004929.1
1 11 21 31 41 51
I I I I I I
MTVFRQENVD DYYDTGEELG SGQFAWKKC REKSTGLQYA AKFIKKRRTK SSRRβVSRED 60 lEREVSILKE IQHPNVITLH EVYENKTDVI LILELVAGGE LFDFLAEKES LTEEEATEFL 120
KQILNGVYYL HSLQIAHFDL KPENIMLLDR NVPKPRIKII DFGLAHKIDF GNEFKNIFGT 180
PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSβASPFLGD TKQETLANVS AVNYEFEDEY 240
FSNTSALAKD FIRRLLVKDP KKRMTIQDSL QHPWIKPKDT QQALSRKASA VNMEKFKKFA 300 0 ARKKWKQSVR LISLCQRLSR SFLSRSNMSV ARSDDTLDEE DSFVMKAIIH AINDDNVPGL 360
QHLLGSLSNY DVNQPNKHGT PPLLIAAGCG NIQILQLLIK RGSRIDVQDK GβSNAVYWAA 420
RHGHVDTLKF LSENKCPLDV KDKSGEMALH VAARYGHADV AQVTCAASAQ IPISRTKEEE 480
TPLHCAAWHG YYSVAKALCE AGCNVNIKNR EGETPLLTAS ARGYHDIVEC LAEHGADLNA 540
CDKDGHIALH LAVRRCQMEV IKTLLSQGCF VDYQDRHGNT PLHVACKDGN MPIWALCEA 600 5 NCNLDISNKY GRTPLHLAAN NGILDWRYL CLMGASVEAL TTDGKTAEDL ARSEQHEHVA 660
GLLARLRKDT HRβLFIQQLR PTQNLQPRIK LKLFβHSGSG KTTLVESLKC GLLRSFFRRR 720
RPRLSSTNSS RFPPSPLASK PTVSVSINNL YPGCENVSVR SRSMMFEPGL TKGMLEVFVA 780
PTHHPHCSAD DQSTKAIDIQ NAYLNGVGDF SVWEFSβNPV YFCCYDYFAA NDPTSIHVW 840
FSLEEPYEIQ LNPVIFWLSF LKSLVPVEEP lAFGGKLKNP LQWLVATHA DIMNVPRPAG 900 0 GEFGYDKDTS LLKEIRNRFG NDLHISNKLF VLDAGASGSK DMKVLRNHLQ EIRSQIVSVC 960
PPMTHLCEKI ISTLPSWRKL NGPNQLMSLQ QFVYDVQDQL NPLASEEDLR RIAQQLHSTG 1020
EINIMQSETV QDVLLLDPRW LCTNVLGKLL SVETPRALHH YRGRYTVEDI QRLVPDSDVE 1080
ELLQILDAMD ICARDLSSGT MVDVPALIKT DNLHRSWADE EDEVMVYGGV RIVPVEHLTP 1140
FPCGIFHKVQ VNLCRWIHQQ STEGDADIRL WVNGCKLANR GAELLVLLVN HGQGIEVQVR 1200 5 GLETEKIKCC LLLDSVCSTI ENVMATTLPG LLTVKHYLSP QQLREHHEPV MIYQPRDFFR 1260
AQTLKETSLT NTMGGYKESF SSIMCFGCHD VYSQASLGMD IHASDLNLLT RRKLSRLLDP 1320
PDPLGKDWCL LAMNLGLPDL VAKYNTNNGA PKDFLPSPLH ALLREWTTYP ESTVGTLMSK 1380
LRELGRRDAA DLLLKASSVF KINLDGNGQE AYASSCNSGT SYNSISSWS R 1431 0 Seq ID NO: C288 Protein Sequence Protein Accession ft: NP_002072.1
1 11 21 31 41 51
I I I I I I 5 MELRARGWWL LCAAAALVAC ARGDPASKSR SCGEVRQIYG AKGFSLSDVP QAEISGEHLR 60
ICPQGYTCCT SEMEENLANR SHAELETALR DSSRVLQAML ATQLRSFDDH FQHLLNDSER 120
TLQATFPGAF GELYTQNARA FRDLYSELRL YYRGANLHLE ETLAEFWARL LERLFKQLHP 180
QLLLPDDYLD CLGKQAEALR PFβEAPRELR LRATRAFVAA RSFVQβLGVA SDWRKVAQV 240
PLGPECSRAV MKLVYCAHCL GVPGARPCPD YCRNVLKGCL ANQADLDAEW RNLLDSMVLI 300 0 TDKFWGTSGV ESVIβSVHTW LAEAINALQD NRDTLTAKVI QGCGNPKVNP QGPGPEEKRR 360
RGKLAPRERP PSGTLEKLVS EAKAQLRDVQ DFWISLPGTL CSEKMALSTA SDDRCWNGMA 420
RGRYLPEVMG DGLANQINNP EVEVDITKPD MTIRQQIMQL KIMTNRLRSA YNGNDVDFQD 480
ASDDGSGSGS 490 5 Seq ID NO: C289 Protein Sequence Protein Accession #: AAH30205.1
1 11 21 31 41 51
_.n I I I 1 I I
D J MIILIYLFLL LWEDTQGWGF KDGIFHNSIW LERAAGVYHR EARSGKYKLT YAEAKAVCEF 60
EGGHLATYKQ LEAARKIGFH VCAAGWMAKG RVGYPIVKPG PNCGFGKTGI IDYGIRLNRS 120
ERWDAYCYNP HAKECGGVFT DPKQIFKSPG FPNEYEDNQI CYWHIRLKYG QRIHLSFLDF 180
DLEDDPGCLA DYVEIYDSYD DVHGFVGRYC GDELPDDIIS TGNVMTLKFL SDASVTAGGF 240
QIKYVAMDPV SKSSQGKNTS TTSTGNKNFL AGRFSHL 277
55
Seq ID NO: C290 Protein Sequence Protein Accession ft: NP 001973.1
1 11 21 31 41 51
60 i i i i i i
MRANDALQVL GLLFSLARGS EVGNSQAVCP GTLNGLSVTG DAENQYQTLY KLYERCE M 60
GNLEIVLTGH NADLSFLQWI REVTGYVLVA MNEFSTLPLP NLR RGTQV YDGKFAIFVM 120
LNYNTNSSHA LRQLRLTQLT EILSGGVYIE KNDKLCHMDT IDWRDIVRDR DAEIWKDNG 180
RSCPPCHEVC KGRCWGPGSE DCQTLTKTIC APQCNGHCFG PNPNQCCHDE CAGβCSGPQD 240
65 TDCFACRHFN DSGACVPRCP QPLVYNKLTF QLEPNPHTKY QYGGVCVASC PHNFWDQTS 300
CVRACPPDKM EVDKNGLKMC EPCGGLCPKA CEGTGSGSRF QTVDSSNIDG FVNCTKILGN 360
LDFLITGLNG DPWHKIPALD PEKLNVFRTV REITGYLNIQ SWPPHMHNFS VFSNLTTIGG 420
RSLYNRGFSL LIMKNLNVTS LGFRSLKEIS AGRIYISANR QLCYHHSLNW TKVLRGPTEE 480
RLDIKHNRPR RDCVAEGKVC DPLCSSGGCW GPGPGQCLSC RNYSRGGVCV THCNFLNGEP 540
70 REFAHEAECF SCHPECQPMG GTATCNGSGS DTCAQCAHFR DGPHCVSSCP HGVLGAKGPI 600
YKYPDVQNEC RPCHENCTQG CKβPELQDCL GQTLVLIGKT HLTMALTVIA GLWIFMMLG 660
GTFLYWRGRR IQNKRAMRRY LERGESIEPL DPSEKANKVL ARIFKETELR KLKVLGSGVF 720
GTVHKGVWIP EGESIKIPVC IKVIEDKSGR QSFQAVTDHM LAIGSLDHAH IVRLLGLCPG 780
SSLQLVTQYL PLGSLLDHVR QHR6ALGPQL LLNWGVQIAK GMYYLEEHGM VHRNLAARNV 840
75 LLKSPSQVQV ADFGVADLLP PDDKQLLYSE AKTPIKWMAL ESIHFGKYTH QSDVWSYGVT 900
VWELMTFGAE PYAGLRLAEV PDLLEKGERL AQPQICTIDV YMVMVKCWMI DENIRPTFKE 960
LANEFTRMAR DPPRYLVIKR ESGPGIAPGP EPHGLTNKKL EEVELEPELD LDLDLEAEED 1020
NLATTTLGSA LSLPVGTLNR PRGSQSLLSP SSGYMPMNQG NLGβSCQESA VSGSSERCPR 1080
PVSLHPMPRG CLASESSEGH VTGSEAELQE KVSMCRSRSR SRSPRPRGDS AYHSQRHSLL 1140
80 TPVTPLSPPG LEEEDVNGYV MPDTHLKGTP SSREGTLSSV GLSSVLGTEE EDEDEEYEYM 1200
NRRRRHSPPH PPRPSSLEEL GYEYMDVGSD LSASLGSTQS CPLHPVPIMP TAGTTPDEDY 1260
EYMNRQRDGG GPGGDYAAMG ACPASEQGYE EMRAFQGPGH QAPHVHYARL KTLRSLEATD 1320
SAFDNPDYWH SRLFPKANAQ RT 1342 Seq ID NO: C291 Protein Sequence Protein Accession ff: NP_001207.1
_ 1 11 21 31 41 51
5 I I I I 1 I
MAPLCPSPWL PLLIPAPAPG LTVQLLLSLL LLMPVHPQRL PRMQEDSPLG GGSSGEDDPL 60
GEEDLPSEED SPREEDPPGE EDLPGEEDLP GEEDLPEVKP KSEEEGSLKL EDLPTVEAPG 120
DPQEPQNNAH RDKEGDDQSH WRYGGDPPWP RVSPACAGRF QSPVDIRPQL AAFCPALRPL 180
ELLGFQLPPL PELRLRNNβH SVQLTLPPGL EMALGPGREY RALQLHLHWG AAGRPGSEHT 240
10 VEGHRFPAEI HWHLSTAFA RVDEALGRPG GLAVLAAFLE EGPEENSAYE QLLSRLEEIA 300
EEGSETQVPG LDISALLPSD FSRYFQYEGS LTTPPCAQGV IWTVFNQTVM LSAKQLHTLS 360
DTLWGPGDSR LQLNFRATQP LNGRVIEASF PAGVDSSPRA AEPVQLNSCL AAGDILALVF 420
GLLFAVTSVA FLVQMRRQHR RGTKββVSYR PAEVAETGA 459
15 Seq ID NO: C292 Protein Sequence Protein Accession ft: NP 004198.1
1 11 21 31 41 51
Iλn M IGGAWDEGP T IβVKAPDGGW G IWAVLFGCFV I ITGFSYAFPK A IVSVFFKELI Q IEFGIGYSDT 60
AWISSILLAM LYGTGPLCSV CVNRFGCRPV MLVGGLFASL GMVAASFCRS IIQVYLTTGV 120
ITGLGLALNF QPSLIMLNRY FSKRRPMANG LAAAGSPVFL CALSPLGQLL QDRYGWRGGF 180
LILGGLLLNC CVCAALMRPL WTAQPGSGP PRPSRRLLDL SVFRDRGFVL YAVAASVMVL 240
GLFVPPVFW SYAKDLGVPD TKAAFLLTIL GFIDIFARPA AGFVAGLGKV RPYSVYLFSF 300
25 SMFFNGLADL AGSTAGDYGG LWFCIFFGI SYGMVβALQF EVLMAIVGTH KFSSAIGLVL 360
LMEAVAVLVG PPSβGKLLDA THVYMYVFIL AGAEVLTSSL ILLLGNFFCI RKKPKEPQPE 420
VAAAEEEKLH KPPADSGVDL REVEHFLKAE PEKNβEWHT PETSV 465
Seq ID NO: C293 Protein Sequence
30 Protein Accession ff: NP 000349.1
1 11 21 31 41 51
I I I I I I
MALFVRLLAL ALALALβPAA TLAGPAKSPY QLVLQHSRLR GRQHGPNVCA VQKVIGTNRK 60
35 YFTNCKQWYQ RKICGKSTVI SYECCPβYEK VPGEKGCPAA LPLSNLYETL GWGSTTTQL 120
YTDRTEKLRP EMEGPGSFTI FAPSNEAWAS LPAEVLDSLV SNVNIELLNA LRYHMVGRRV 180
LTDELKHGMT LTSMYQNSNI QIHHYPNGIV TVNCARLLKA DHHATNβWH LIDKVISTIT 240
NNIQQIIEIE DTFETLRAAV AASGLNTMLE βNGQYTLLAP TNEAFEKIPS ETLNRILGDP 300
EALRDLLNNH ILKSAMCAEA IVAGLSVETL EGTTLEVGCS GDMLTINGKA IISNKDILAT 360
40 NGVIHYIDEL LIPDSAKTLF ELAAESDVST AIDLFRQAGL GNHLSGSERL TLLAPLNSVF 420
KDGTPPIDAH TRNLLRNHII KDQLASKYLY HGQTLETLGG KKLRVFVYRN SLCIENSCIA 480
AHDKRGRYGT LFTMDRVLTP PMGTVMDVLK GDNRFSMLVA AIQSAβLTET LNREGVYTVF 540
APTNEAFRAL PPRERSRLLG DAKELANILK YHIGDEILVS GGIGALVRLK SLQGDKLEVS 600
LKNNWSVNK EPVAEPDIMA TNGWHVITN VLQPPANRPQ ERGDELADSA LEIFKQASAF 660
45 SRASQRSVRL APVYQKLLER MKH 683
Seq ID NO: C294 Protein Sequence Protein Accession ft: NP 006527.1
50 1 11 21 31 41 51
I 1 I / I I I
MTQRSIAGPI CNLKFVTLLV ALSSELPFLG AGVQLQDNGY NGLLIAINPQ VPENQNLISN 60
IKEMITEASF YLFNATKRRV FFRNIKILIP ATWKANNNSK IKQESYEKAN VIVTDWYGAH 120
GDDPYTLQYR GCGKEGKYIH FTPNFLLNDN LTAGYGSRGR VFVHEWAHLR WGVFDEYNND 180
55 KPFYINGQNQ IKVTRCSSDI TGIFVCEKGP CPQENCIISK LFKEGCTFIY NSTQNATASI 240
MFMQSLSSW EFCNASTHNQ EAPNLQNQMC SLRSAWDVIT DSADFHHSFP MNGTELPPPP 300
TFSLVQAGDK WCLVLDVSS KMAEADRLLQ LQQAAEFYLM QIVEIHTFVG IASFDSKGEI 360
RAQLHQINSN DDRKLLVSYL PTTVSAKTDI SICSGLKKGF EWEKLNGKA YGSVMILVTS 420
GDDKLLGNCL PTVLSΞGSTI HSIALGSSAA PNLEELSRLT GGLKFFVPDI SNSNSMIDAF 480
60 SRISSGTGDI FQQHIQLEST GENVKPHHQL KNTVTVDNTV GNDTMFLVTW QASGPPEIIL 540
FDPDGRKYYT NNFITNLTFR TASLWIPGTA KPGHWTYTLN NTHHSLQALK VTVTSRASNS 600
AVPPATVEAF VERDSLHFPH PVMIYANVKQ GFYPILNATV TATVEPETGD PVTLRLLDDG 660
AGADVIKNDG IYSRYFFSFA ANGRYSLKVH VNHSPSISTP AHSIPGSHAM YVPGYTANGN 720
._ IQMNAPRKSV GRNEEERKWG FSRVSSGGSF SVLGVPAGPH PDVFPPCKII DLEAVKVEEE 780
65 LTLSWTAPGE DFDQGQATSY EIRMSKSLQN IQDDFNNAIL VNTSKRNPQQ AGIREIFTFS 840
PQISTNGPEH QPNGETHESH RIYVAIRAMD RNSLQSAVSN IAQAPLFIPP NSDPVPARDY 900
LILKGVLTAM GLIGIICLII WTHHTLSRK KRADKKENGT KLL 943
Seq ID NO: C295 Protein Sequence
70 Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MKFLLILLLQ ATASGALPLN SSTSLEKNNV LFGERYLEKF YGLEINKLPV TKMKYSGNLM 60
75 KEKIQEMQHF LGLKVTGQLD TSTLEMMHAP RCGVPDVHHF REMPGGPVWR KHYITYRINN 120
YTPDMNREDV DYAIRKAFQV WSNVTPLKFS KINTGMADIL WFARGAHGD FHAFDGKGGI 180
LAHAFGPGSG IGGDAHFDED EFWTTHSGGT NLFLTAVHEI GHSLGLGHSS DPKAVMFPTY 240
KYVDINTFRL SADDIRGIQS LYGDPKENQR LPNPDNSEPA LCDPNLSFDA VTTVGNKIFF 300
FKDRFFWLKV SERPKTSVNL ISSLWPTLPS GIEAAYEIEA RNQVFLFKDD KYWLISNLRP 360
80 EPNYPKSIHS FGFPNFVKKI DAAVFNPRFY RTYFFVDNQY WRYDERRQMM DPGYPKLITK 420
NFQGIGPKID AVFYSKNKYY YFFQGSNQFE YDFLLQRITK TLKSNSWFGC . 470
Seq ID NO: C296 Protein Sequence Protein Accession ft: Eos sequence 1 11 21 31 41 51
I I I I I I
MKFLLILLLQ ATASGALPLN SSTSLEKNNV LFGERYLEKF YGLEINKLPV TKMKYSGNLM 60
KEKIQEMQHF LGLKVTGQLD TSTLEMMHAP RCGVPDVHHF REMPGGPVWR KHYITYRINN 120
YTPDMNREDV DYAIRKAFQV WSNVTPLKFS KINTGMADIL WFARGAHGD FHAFDGKGGI 180
LAHAFGPGSG IGGDAHFDED EFWTTHSGGT NLFLTAVHAI GHSLGLGHSS DPKAVMFPTY 240
KYVDINTFRL ΞADDIRGIQS LYGDPKENQR LPNPDNSEPA LCDPNLSFDA VTTVGNKIFF 300
FKDRFFWLKV SERPKTSVNL ISSLWPTLPS GIEAAYEIEA RNQVFLFKDD KYWLISNLRP 360
EPNYPKSIHS FGFPNFVKKI DAAVFNPRFY RTYFFVDNQY WRYDERRQMM DPGYPKLITK 420
NFQGIGPKID AVFYSKNKYY YFFQGSNQFE YDFLLQRITK TLKSNSWFGC 470
Seq ID NO: C297 Protein Sequence Protein Accession ff: NP_008883.1
1 11 21 31 41 51
I I I I I I
MAKDNSTVRC FQGLLIFGNV IIGCCGIALT AECIFFVSDQ HSLYPLLEAT DNDDIYGAAW 60
IGIFVβlCLF CLSVLGIVGI MKSSRKILLA YFILMFIVYA FEVASCITAA TQRDFFTPNL 120
FLKQMLERYQ NNSPPNNDDQ WKNNGVTKTW DRLMLQDNCC GVNGPSDWQK YTSAFRTENN 180
DADYPWPRQC CVMNNLKEPL NLEACKLGVP GFYHNQGCYE LISGPMNRHA WGVAWFGFAI 240
LCWTFWVLLG TMFYWSRIEY 260
Seq ID NO: C298 Protein Sequence Protein Accession ff: NP 001784.2
1 11 21 31 41 51
M IGLPRGPLAS LILLLQVCWLQ CIAASEPCRAV FIREAEVTLEA GIGAEQEPGQA LIGKVFMGCPG 60 QEPALFSTDN DDFTVRNGET VQERRSLKER NPLKIFPSKR ILRRHKRDWV VAPISVPENG 120
KGPFPQRLNQ LKSNKDRDTK IFYSITGPGA DSPPEGVFAV EKETGWLLLN KPLDREEIAK 180
YELFGHAVSE NGASVEDPMN ISIIVTDQND HKPKFTQDTF RGSVLEGVLP GTSVMQVTAT 240
DEDDAIYTYN G AYSIHSQ EPKDPHDLMF TIHRSTGTIS VISSGLDREK VPEYTLTIQA 300
TDMDGDGSTT TAVAWEILD ANDNAPMFDP QKYEAHVPEN AVGHEVQRLT VTDLDAPNSP 360 AWRATYLIMG GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL 420
PTSTATIWH VEDVNEAPVF VPPSKWEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR 480
DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTG TGTLLLTLID 540
VNDHGPVPEP RQITICNQSP VRQVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD 600 TWLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL 660 GAVLALLFLL LVLLLLVRKK RKIKEPLLLP EDDTRDNVFY YGEEGGGEED QDYDITQLHR 720
GLEARPEWL RNDVAPTIIP TPMYRPRPAN PDEIGNFIIE NLKAANTDPT APPYDTLLVF 780
DYEGSGSDAA SLSSLTSSAS DQDQDYDYLN EWGSRFKKLA DMYGGGEDD 829
Seq ID NO: C299 Protein Sequence Protein Accession #: NP 005620.1
1 11 21 31 41 51
I I I I I I
- MAKKSAENβl YSVSGDEKKG PLIAPGPDGA PAKGDGPVGL GTPGGRLAVP PRETWTRQMD 60 FIMSCVβFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS 120
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD 180
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA LNWEVTLCLL 240
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLWLLVRGV LLPGALDGII YYLKPDWSKL 300
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFWF 360 5 SILGFMAAEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV 420
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDGGMYVF QLFDYYSASG 480
TTLLWQAFWE CVWAWVYGA DRFMDDIACM IGYRPCPWMK WCWSFFTPLV CMGIFIFNW 540
YYEPLVYNNT YVYPWWGEAM GWAFALSSML CVPLHLLGCL LRAKGTMAER WQHLTQPIWG 600
LHHLEYRAQD ADVRGLTTLT PVSESSKVW VESVM 635 0
Seq ID NO: C300 Protein Sequence Protein Accession ft: NP 006507.1 _ 1 11 21 31 41 51 5 i i i i i i
MEPSSKKLTG RLMLAVGGAV LGSLQFGYNT GVINAPQKVI EEFYNQTWVH RYGESILPTT 60
LTTLWSLSVA IFSVGGMIGS FSVGLFVNRF GRRNSMLMMN LLAFVSAVLM GFSKLGKSFE 120
MLILGRFIIG VYCGLTTGFV PMYVGEVSPT AFRGALGTLH QLGIWGILI AQVFGLDSIM 180
GNKDLWPLLL SIIFIPALLQ CIVLPFCPES PRFLLINRNE ENRAKSVLKK LRGTADVTHD 240 0 LQEMKEESRQ MMREKKVTIL ELFRSPAYRQ PILIAWLQL SQQLΞGINAV FYYSTSIFEK 300
AGVQQPVYAT IGSGIVNTAF TWSLFWER AGRRTLHLIG LAGMAGCAIL MTIALALLEQ 360
LPWMSYLSIV AIFGFVAFFE VGPGPIPWFI VAELFSQGPR PAAIAVAGFS NWTSNFIVGM 420
CFQYVEQLCG PYVFIIFTVL LVLFFIFTYF KVPETKGRTF DEIASGFRQG GASQSDKTPE 480
ELFHPLGADS QV 492 5
Seq ID NO: C301 Protein Sequence Protein Accession ft: XP_035292.2
1 11 21 31 41 51 0
M IAGAGPKRRA LIAAPAAEEKE EIAREKMLAAK SIADGSAPAGE GIEGVTLQRNI TILLNGVAIIV 60
GTIIGSGIFV TPTGVLKEAG SPGLALWWA ACGVFSIVGA LCYAELβTTI SKSββDYAYM 120
LEVYβSLPAF LKLWIELLII RPSSQYIVAL VFATYLLKPL FPTCPVPEEA AKLVACLCVL 180
LLTAVNCYSV KAATRVQDAF AAAKLLALAL IILLGFVQIG KGDVSNLDPN FSFEGTKLDV 240 GNIVLALYSG LFAYGGWNYL NFVTEEMINP YRNLPLAIII SLPIVTLVYV LTNLAYFTTL 300
STEQMLSSEA VAVDFGNYHL GVMSWIIPVF VGLSCFGSVN GSLFTSSRLF FVGSREGHLP 360
SILSMIHPQL LTPVPSLVFT CVMTLLYAFS KDIFSVINFF SFFNWLCVAL AIIβMIWLRH 420
RKPELERPIK 'VNLALPVFFI LACLFLIAVS FWKTPVECGI GFTIILSGLP VYFFGVWWKN 480
KPKWLLQGIF STTVLCQKLM Q PQET 507
Seq ID NO: C302 Protein Sequence Protein Accession ft: NP 005259.1
11 21 31 41 51
MNWSIFEGLL SlGVNKYSTAF GlRIWLSLVFI FlRVLVYLVTA ElRVWSDDHKD FlDCNTRQPGC 60 SNVCFDEFFP VSHVRLWALQ LILVTCPSLL WMHVAYREV QEKRHREAHG ENSGRLYLNP 120 GKKRGβLWWT YVCSLVFKAS VDIAFLYVFH SFYPKYILPP WKCHADPCP NIVDCFISKP 180 SEKNIFTLFM VATAAICILL NLVELIYLVS KRCHECLAAR KAQAMCTGHH PHGTTSSCKQ 240 DDLLSβDLIF LGSDSHPPLL PDRPRDHVKK TIL 273
Seq ID NO: C303 Protein Sequence Protein Accession ft: NP_005121.1
1 11 21 31 41 51
I I I I I I
MKICSLTLLS FLLLAAQVLL VEGKKKVKNG LHSKWSEQK DTLGNTQIKQ KSRPGNKGKF 60
VTKDQANCRW AATEQEEGIS LKVECTQLDH EFSCVFAGNP TSCLKLKDER VYWKQVARNL 120
RSQKDICRYS KTAVKTRVCR KDFPESSLKL VSSTLFGNTK PRKEKTEMSP REHIKGKETT 180
PSSLAVTQTM ATKAPECVED PDMANQRKTA LEFCGETWSS LCTFFLSIVQ DTSC 234
Seq ID NO: C304 Protein Sequence Protein Accession #: AAH22542
1 11 21 31 41 51
I I I I I I
MCSEIILRQE VLKDGFHRDL LIKVKFGESI EDLHTCRLLI KQDIPAGLYV DPYELASLRE 60 RNITEAVMVS ENFDIEAPNY LSKESEVLIY ARRDSQCIDC FQAFLPVHCR YHRPHSEDGE 120
ASIWNNPDL LMFCDQAGSR RMIRFRFDSF DKTIEFPILK CWAHSEVAAP CALENEDICQ 180
WNKMKYKSVY KNVILQVPVG LTVHTSLVCS VTLLITILCS KKKKK 225
Seq ID NO: C305 Protein Sequence Protein Accession ft: NP 004985.1
11 21 31 41 51
I I I I I
MSLWQPLVLV LLVLGCCFAA PRQRQSTLVL FPGDLRTNLT DRQLAEEYLY RYGYTRVAEM 60 RGESKSLGPA LLLLQKQLSL PETGELDSAT LKAMRTPRCG VPDLGRFQTF EGDLKWHHHN 120 ITYWIQNYSE DLPRAVIDDA FARAFALWSA VTPLTFTRVY SRDADIVIQF GVAEHGDGYP 180 FDGKDGLLAH AFPPGPGIQG DAHFDDDELW SLGKGVWPT RFGNADβAAC HFPFIFEGRS 240 YSACTTDGRS DGLPWCSTTA NYDTDDRFGF CPSERLYTRD GNADGKPCQF PFIFQGQSYS 300 ACTTDGRSDG YRWCATTANY DRDKLFGFCP TRADSTVMGβ NSAGELCVFP FTFLGKEYST 360 CTSEGRGDGR LWCATTSNFD SDKKWGFCPD QGYSLFLVAA HEFGHALGLD HSSVPEALMY 420 PMYRFTEβPP LHKDDVNGIR HLYGPRPEPE PRPPTTTTPQ PTAPPTVCPT GPPTVHPSER 480 PTAβPTβPPS AGPTGPPTAG PSTATTVPLS PVDDACNVNI FDAIAEIGNQ LYLFKDGKYW 540 RFSEGRGSRP QGPFLIADK PALPRKLDS'V FEEPLSKKLF FFSGRQVWVY TGASVLGPRR 600 LDKLGLGADV AQVTGALRSG RGKMLLFSGR RLWRFDVKAQ MVDPRSASEV DRMFPGVPLD 660 THDVFQYREK AYFCQDRFYW RVSSRSELNQ VDQVGYVTYD ILQCPED 707
Seq ID NO: C306 Protein Sequence Protein Accession ft: NP 000204
11 21 31 41 51
I I I I I
MAGPRPSPWA RLLLAALISV SLSGTLANRC KKAPVKSCTE CVRVDKDCAY CTDEMFRDRR 60 CNTQAELLAA GCQRESIWM ESSFQITEET QIDTTLRRSQ MSPQβLRVRL RPGEERHFEL 120 EVFEPLESPV DLYILMDFSN SMSDDLDNLK KMGQNLARVL SQLTSDYTIβ FGKFVDKVSV 180 PQTDMRPEKL KEPWPNSDPP FSFKNVISLT EDVDEFRNKL QGERISGNLD APEGGFDAIL 240 QTAVCTRDIG WRPDSTHLLV FSTESAFHYE ADβANVLAGI MSRNDERCHL DTTGTYTQYR 300 TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHTYF PVSSLGVLQE DSSNIVELLE 360 EAFNRIRSNL DIRALDSPRG LRTEVTSKMF QKTRTGSFHI RRGEVGIYQV QLRALEHVDG 420 THVCQLPEDQ KGNIHLKPSF SDGLKMDAGI ICDVCTCELQ KEVRSARCSF NGDFVCβQCV 480 CSEGWSGQTC NCSTGSLSDI QPCLREGEDK PCSGRGECQC GHCVCYGEGR YEGQFCEYDN 540 FQCPRTSGFL CNDRGRCSMG QCVCEPGWTG PSCDCPLSNA TCIDSNGGIC NGRGHCECGR 600 CHCHQQSLYT DTICEINYSA IHPGLCEDLR SCVQCQAWGT GEKKGRTCEE CNFKVKMVDE 660 LKRAEEVWR CSFRDEDDDC TYSYTMEGDG APGPNSTVLV HKKKDCPPβS FWWLIPLLLL 720 LLPLLALLLL LCWKYCACCK ACLALLPCCN RGHMVGFKED HYMLRENLMA SDHLDTPMLR 780 SGNLKGRDW RWKVTNNMQR PGFATHAASI NPTELVPYGL SLRLARLCTE NLLKPDTREC 840 AQLRQEVEEN LNEVYRQISG VHKLQQTKFR QQPNAGKKQD HTIVDTVLMA PRSAKPALLK 900 LTEKQVEQRA FHDLKVAPGY YTLTADQDAR GMVEFQEGVE LVDVRVPLFI RPEDDDEKQL 960 LVEAIDVPAG TATLGRRLVN ITIIKEQARD WSFEQPEFS VSRGDQVARI PVIRRVLDGG 1020 KSQVSYRTQD GTAQGNRDYI PVEGELLFQP GEAWKELQVK LLELQEVDSL LRGRQVRRFH 1080 VQLSNPKFGA HLGQPHSTTI IIRDPDELDR SFTSQMLSSQ PPPHGDLGAP QNPNAKAAGS 1140 RKIHFNWLPP SGKPMGYRVK YWIQGDSESE AHLLDSKVPS VELTNLYPYC DYEMKVCAYG 1200 AQGEGPYSSL VSCRTHQEVP SEPGRLAFNV VSSTVTQLSW AEPAETNGEI TAYEVCYGLV 1260 NDDNRPIGPM KKVLVDNPKN RMLLIENLRE SQPYRYTVKA RNGAGWGPER EAIINLATQP 1320 KRPMSIPIIP DIPIVDAQSG EDYDSFLMYS DDVLRSPSGS QRPSVSDDTG CGWKFEPLLG 1380 EELDLRRVTW RLPPELIPRL SASSGRSSDA EAPTAPRTTA ARAβRAAAVP RSATPGPPGE 1440 HLVNGRMDFA FPGSTNSLHR MTTTSAAAYG THLSPHVPHR VLSTSSTLTR DYNSLTRSEH 1500 SHSTTLPRDY STLTSVSSHD SRLTAGVPDT PTRLVFSALG PTSLRVSWQE PRCERPLQGY 1560 SVEYQLLNGG ELHRLNIPNP AQTSVWEDL LPNHSYVFRV RAQSQEGWGR EREβVITIES 1620 QVHPQΞPLCP LPGSAFTLST PSAPGPLVFT ALSPDSLQLS WERPRRPNGD IVβYLVTCEM 1680 AQGGGPATAF RVDGDSPESR LTVPGLSENV PYKFKVQART TEGFGPEREG IITIESQDGG 1740 PFPQLGSRAG LFQHPLQSEY SSITTTHTSA TEPFLVDGLT LGAQHLEAGG SLTRHVTQEF 1800 VSRTLTTSGT LSTHMDQQFF QT 1822
Seq ID NO: C307 Protein Sequence Protein Accession ff : NP 076404.1
FVASILLN 60
Figure imgf001355_0001
LCRYTSVL 120
FYANMYTSIV FLGLISIDRY LK KPFβDS RMYSITFTKV LSVCVWVIMA VLSLPNIILT 180
NGQPTEDNIH DCSKLKSPLG VKWHTAVTYV NSCLFVAVLV ILIGCYIAIS RYIHKSSRQF 240
ISQSSRKRKH NQSIRVWAV FFTCFLPYHL CRIPFTFSHL DRLLDESAQK ILYYCKEITL 300
FLSACNVCLD PIIYFFMCRS FSRRLFKKSN IRTRSESIRS LQSVRRSEVR IYYDYTDV 358
Seq ID NO: C308 Protein Sequence Protein Accession ff: NP 065840.1
1 11 21 31 41 51 1 1 | 1 | 1 |1 1 | 1
MVWCLGLAVL SLVISQGADG RGKPEWSW GRAEESWLG CDLLPPAGRP PLHVIEWLRF 60
GFLLPIFIQF GLYSPRIDPD YVGRVRLQKG ASLQIEGLRV EDQGWYECRV FFLDQHIPED 120
DFANGSWVHL TVNSPPQFQE TPPAVLEVQE LEPVTLRCVA RGSPLPHVTW KLRGKDLGQG 180
QGQVQVQNGT LRIRRVERGS SGVYTCQASS TEGSATHATQ LLVLGPPVIV VPPKNSTVNA 240
SQDVSLACHA EAYPANLTYS WFQDNINVFH ISRLQPRVQI LVDGSLRLLA TQPDDAGCYT 300
CVPSNGLLHP PSASAYLTVL CMPGVIRCPV RANPPLLFVS WTKDGKALQL DKFPGWSQGT 360
EGSLIIALGN EDALGEYSCT PYNSLGTAGP SPVTRVLLKA PPAFIERPKE EYFQEVGREL 420
LIPCSAQGDP PPWSWTKVG RGLQGQAQVD SNSSLILRPL TKEAHGHWEC SASNAVARVA 480
TSTNVYVLGT SPHWTNVSV VALPKGANVS WEPGFDGGYL QRFSVWYTPL AKRPDRMHHD 540
WVSLAVPVβA AHLLVPGLQP HTQYQFSVLA QNKLGSGPFS EIVLSAPEGL PTTPAAPGLP 600
PTEIPPPLSP PRGLVAVRTP RGVLLHWDPP ELVPKRLDGY VLEGRQGSQG WEVLDPAVAG 660
TETELLVPGL IKDVLYEFRL VAFAβSFVSD PSNTANVSTS GLEVYPSRTQ LPGLLPQPVL 720
AGWGGVCFL GVAVLVSILA GCLLNRRRAA RRRRKRLRQD PPLIFSPTGK SAAPSALGSG 780
SPDSVAKLKL QGSPVPSLRQ SLLWGDPAGT PSPHPDPPSS RβPLPLEPIC RGPDGRFVMG 840
PTVAAPQERS GREQAEPRTP AQRLARSFDC SSSSPSGAPQ PLCIEDISPV APPPAAPPSP 900
LPGPGPLLQY LSLPFFREMN VDGDWPPLEE PSPAAPPDYM DTRRCPTSSF LRSPETPPVS 960
PRESLPGAW GAGATAEPPY TALADWTLRE RLLPGLLPAA PRGSLTSQSS GRGSASFLRP 1020
PSTAPSAGGS YLSPAPGDTS SWASGPERWP RREHWTVSK RRNTSVDENY EWDSEFPGDM 1080
ELLETLHLGL ASSRLRPEAE TELGVKTPEE GCLLNTAHVT GPEARCAALR EEFLAFRRRR 1140
DATRARLPAY RQPVPHPEQA TLL 1163
Seq ID NO: C309 Protein Sequence Protein Accession #:
11 21 31 41 51
I I I I I I
MLTKPLQGPP APPGTPTPPP GGKDREAFEA EYRLGPLLGK GGFGTVFAGH RLTDRLQVAI 60 KVIPRNRVLG WSPLSDSVTC PLEVALLWKV GAGGGHPGVI RLLDWFETQE GFMLVLERPL 120 PAQDLFDYIT EKGPLGEGPS RCFFGQWAA IQHCHSRGW HRDIKDENIL IDLRRGCAKL 180 IDFGSGALLH DEPYTDFDβT RVYSPPEWIS RHQYHALPAT VWSLGILLYD MVCGDIPFER 240 DQEILEAELH FPAHVSPDCC ALIRRCLAPK PSSRPSLEEI LLDPWMQTPA EDVTPQPLQR 300 RPCPFGLVLA TLSLAWPGLA PNGQKSHPMA MSQG 334
Seq ID NO: C310 Protein Sequence Protein Accession ff: NP 002501.1
1 11 21 31 41 51 1 1 | 1 1 1 11 11 11
MECLYYFLGF LLLAARLPLD AAKRFHDVLG NERPSAYMRE HNQLNGWSSD ENDWNEKLYP 60
VWKRGDMRWK NSWKGGRVQA VLTSDSPALV GSNITFAVNL IFPRCQKEDA NGNIVYEKNC 120
RNEAGLSADP YVYNWTAWSE DSDGENGTGQ SHHNVFPDGK PFPHHPGWRR WNFIYVFHTL 180
GQYFQKLGRC SVRVSVNTAN VTLGPQLMEV TVYRRHGRAY VPIAQVKDVY WTDQIPVFV 240
TMFQKNDRNS SDETFLKDLP IMFDVLIHDP SHFLNYSTIN YKWSFGDNTG LFVSTNHTVN 300
HTYVLNGTFS LNLTVKAAAP GPCPPPPPPP RPSKPTPSLG PAGDNPLELS RIPDENCQIN 360
RYGHFQATIT IVEGILEVNI IQMTDVLMPV PWPESSLIDF WTCQGSIPT EVCTIISDPT 420
CEITQNTVCS PVDVDEMCLL TVRRTFNGSG TYCVNLTLGD DTSLALTSTL ISVPDRDPAS 480
PLRMANSALI SVGCLAIFVT VISLLVYKKH KEYNPIENSP βN RSKGLS VFLNRAKAVF 540
FPGNQEKDPL LKNQEFKGVS 560
Seq ID NO: C311 Protein Sequence Protein Accession #: Eos seq
11 21 31 41 51
I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTβK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360
HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLI'VDMPT DNPELDLFPE 420
LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480
RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEβTSASLND 540
GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600
ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660
TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720
TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNEASNSS HESRIGLAEG LESEKKAVIP 780
LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR VISTPPTPIF PISDDVGAIP 840
IKHFPKHVAD LHASSGFTEE FEEVQSCTVD LGITADSSNH PDNKHKNRYI NIVAYDHSRV 900
KLAQLAEKDG KLTDYINANY VDGYNRPKAY IAAQGPLKST AEDFWRMIWE HNVEVIVMIT 960
NLVEKGRRKC DQYWPADGSE EYGNFLVTQK SVQVLAYYTV RNFTLRNTKI KKGSQKGRPS 1020
GRWTQYHYT QWPDMGVPEY SLPVLTFVRK AAYAKRHAVG P VHCSAGV GRTGTYIVLD 1080
SMLQQIQHEβ TVNIFGFLKH IRSQRNYLVQ TEEQYVFIHD TLVEAILSKE TEVLDSHIHA 1140
YVNALLIPβP AGKTKLEKQF QLLSQSNIQQ SDYSAALKQC NREKNRTSSI IPVERSRVGI 1200
SSLSGEGTDY INASYIMGYY QSNEFIITQH PLLHTIKDFW RMIWDHNAQL WMIPDGQNM 1260
AEDEFVYWPN KDEPINCESF KVTLMAEEHK CLSNEEKLII QDFILEATQD DYVLEVRHFQ 1320
CPKWPNPDSP ISKTFELISV IKEEAANRDG PMIVHDEHGG VTAGTFCALT TLMHQLEKEN 1380
SVDVYQVAKM INLMRPGVFA DIEQYQFLYK VILSLVSTRQ EENPSTSLDS NGAALPDGNI 1440
AESLESLV 1448
Seq ID NO: C312 Protein Sequence Protein Accession ft: XP 031379
11 21 31 41 51
I " I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60
QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120
FKAΞKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180
ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240
TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300
TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360
HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420
LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480
RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540
GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600
ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660
TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720
TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNGETPLQ PSYSSEVFPL VTPLLLDNQI 780
LNTTPAASSS DSALHATPVF PSVDVSFESI LSSYDGAPLL PFSSASFSSE LFRHLHTVSQ 840
ILPQVTSATE SDKVPLHASL PVAGβDLLLE PSLAQYSDVL STTHAASETL EFGSESGVLY 900
KTLMFSQVEP PSSDAMMHAR SSGPEPSYAL SDNEGSQHIF TVSYSSAIPV HDSVGVTYQG 960
SLFSGPSHIP IPKSSLITPT ASLLQPTHAL SGDGEWSGAS SDSEFLLPDT DGLTALNISS 1020
PVSVAEFTYT TSVFGDDNKA LSKSEIIYGN ETELQIPSFN EMVYPSESTV MPNMYDNVNK 1080
LNASLQETSV SISSTKGMFP GSLAHTTTKV FDHEISQVPE NNFSVQPTHT VSQASGDTSL 1140
KPVLSANSEP ASSDPASSEM LSPSTQLLFY ETSASFSTEV LLQPSFQASD VDTLLKTVLP 1200
AVPSDPILVE TPKVDKISST MLHLIVSNSA SSENMLHSTS VPVFDVSPTS HMHSASLQGL 1260
TISYASEKYE PVLLKSESSH QWPSLYSND ELFQTANLEI NQAHPPKGRH VFATPVLSID 1320
EPLNTLINKL IHSDEILTST KSSVTGKVFA GIPTVASDTF VSTDHSVPIG NGHVAITAVS 1380
PHRDGSVTST KLLFPSKATS ELSHSAKSDA GLVGGGEDGD TDDDGDDDDD DRGSDGLSIH 1440
KCMSCSSYRE SQEKVMNDSD THENSLMDQN NPISYSLSEN SEEDNRVTSV SSDSQTGMDR 1500
SPGKSPSANG LSQKHNDGKE ENDIQTGSAL LPLSPESKAW AVLTSDEESG SGQGTSDSLN 1560
ENETSTDFSF ADTNEKDADG ILAAGDSEIT PGFPQSPTSS VTSENSEVFH VSEAEASNSS 1620
HESRIGLAEG LESEKKAVIP LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR 1680
VISTPPTPIF PISDDVGAIP IKHFPKHVAD LHASSGFTEE FETLKEFYQE VQSCTVDLGI 1740
TADSSNHPDN KHKNRYINIV AYDHSRVKLA QLAEKDGKLT DYINANYVDG YNRPKAYIAA 1800
QGPLKSTAED FWRMIWEHNV EVIVMITNLV EKGRRKCDQY WPADGSEEYG NFLVTQKSVQ 1860
VLAYYTVRNF TLRNTKIKKG SQKGRPSGRV VTQYHYTQWP DMGVPEYSLP VLTFVRKAAY 1920
AKRHAVGPW VHCSAGVGRT GTYIVLDSML QQIQHEGTVN IFGFLKHIRS QRNYLVQTEE 1980
QYVFIHDTLV EAILSKETEV LDSHIHAYVN ALLIPGPAGK TKLEKQFQLL SQSNIQQSDY 2040
SAALKQCNRE KNRTSSIIPV ERSRVGISSL SGEGTDYINA SYIMGYYQSN EFIITQHPLL 2100
HTIKDFWRMI WDHNAQLWM IPDGQNMAED EFVYWPNKDE PINCESFKVT LMAEEHKCLS 2160
NEEKLIIQDF ILEATQDDYV LEVRHFQCPK WPNPDSPISK TFELISVIKE EAANRDGPMI 2220
VHDEHGGVTA GTFCALTTLM HQLEKENSVD VYQVAKMINL MRPGVFADIE QYQFLYKVIL 2280
SLVSTRQEEN PSTSLDSNGA ALPDGNIAES LESLV 2315
Seq ID NO: C313 Protein Sequence Protein Accession ft: NP 002842
11 21 31 41 51
I I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 6SKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNAEAΞNS SHESRIGLAE GLESEKKAVI 780 PLVIVSALTF ICLWLVGIL IYWRKCFQTA HFYLEDSTSP RVISTPPTPI FPISDDVGAI 840 PIKHFPKHVA DLHASSGFTE EFETLKEFYQ EVQSCTVDLG ITADSSNHPD NKHKNRYINI 900 VAYDHSRVKL AQLAEKDGKL TDYINANYVD GYNRPKAYIA AQβPLKSTAE DFWRMIWEHN 960 VEVIVMITNL VEKGRRKCDQ YWPADGSEEY GNFLVTQKSV QVLAYYTVRN FTLRNTKIKK 1020 βSQKβRPSβR WTQYHYTQW PDMGVPEYSL PVLTFVRKAA YAKRHAVGPV WHCSAGVGR 1080 TGTYIVLDSM LQQIQHEGTV NIFGFLKHIR SQRNYLVQTE EQYVFIHDTL VEAILSKETE 1140 VLDSHIHAYV NALLIPGPAG KTKLEKQFQL LSQSNIQQSD YSAALKQCNR EKNRTSSIIP 1200 VERSRVGISS LSGEGTDYIN ASYIMGYYQS NEFIITQHPL LHTIKDFWRM IWDHNAQLW 1260 MIPDGQNMAE DEFVYWPNKD EPINCESFKV TLMAEEHKCL SNEEKLIIQD FILEATQDDY 1320 VLEVRHFQCP KWPNPDSPIS KTFELISVIK EEAANRDGPM IVHDEHGGVT AGTFCALTTL 1380 MHQLEKENSV DVYQVAKMIN LMRPGVFADI EQYQFLYKVI LSLVSTRQEE NPSTSLDSNG 1440 AALPDGNIAE SLESLV 1456
Seq ID NO: C314 Protein Sequence Protein Accession # : Eos sequence
11 21 31 41 51
I I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 MVFKASKITF HWGKCNMSSD GSEHSLEGQK FPLEMQIYCF DADRFSSFEE AVKGKGKLRA 180 LSILFEVGTE ENLDFKAIID GVESVSRFGK QAALDPFILL NLLPNSTDKY YIYNGSLTSP 240 PCTDTDWIVF KDTVSISESQ LAVFCEVLTM QQSGYVMLMD YLQNNFREQQ YKFSRQVFSS 300 YTGKEEIHEA VCSSEPENVQ ADPENYTSLL VTWERPRWY DTMIEKFAVL YQQLDGEDQT 360 KHEFLTDGYQ DLGAILNNLL PNMSYVLQIV AICTNGLYGK YSDQLIVDMP TDNPELDLFP 420 ELIβTEEIIK EEEEGKDIEE GAIVNPGRDS ATNQIRKKEP QISTTTHYNR IGTKYNEAKT 480 NRSPTRβSEF SGKGDVPNTS LNSTSQPVTK LATEKDISLT SQTVTELPPH TVEGTSASLN 540 DβSKTVLRSP HMNLSGTAES LNTVSITEYE EESLLTSFKL DTGAEDSSGS SPATSAIPFI 600 SENISQGYIF SSENPETITY DVLIPESARN ASEDSTSSGS EESLKDPSME GNVWFPSSTD 660 ITAQPDVGSG RESFLQTNYT EIRVDESEKT TKSFSAGPVM SQGPSVTDLE MPHYSTFAYF 720 PTEVTPHAFT PSSRQQDLVS TVNWYSQTT QPVYNEASNS SHESRIGLAE GLESEKKAVI 780 PLVIVSALTF ICLWLVGIL IYWRKCFQTA HFYLEDSTSP RVISTPPTPI FPISDDVGAI 840 PIKHFPKHVA DLHASSGFTE EFETLKEFYQ EVQSCTVDLG ITADSSNHPD NKHKNRYINI 900 VAYDHSRVKL AQLAEKDGKL TDYINANYVD GYNRPKAYIA AQGPLKSTAE DFWRMIWEHN 960 VEVIVMITNL VEKGRRKCDQ YWPADGSEEY GNFLVTQKSV QVLAYYTVRN FTLRNTKIKK 1020 GSQKGRPSGR WTQYHYTQW PDMGVPEYSL PVLTFVRKAA YAKRHAVGPV WHCSAGVGR 1080 TGTYIVLDSM LQQIQHEGTV NIFGFLKHIR SQRNYLVQTE EQYVFIHDTL VEAILSKETE 1140 VLDSHIHAYV NALLIPGPAβ KTKLEKQFQL LSQSNIQQSD YSAALKQCNR EKNRTSSIIP 1200 VERSRVGISS LSβEGTDYIN ASYIMGYYQS NEFIITQHPL LHTIKDFWRM IWDHNAQLW 1260 MIPDGQNMAE DEFVYWPNKD EPINCESFKV TLMAEEHKCL SNEEKLIIQD FILEATQDDY 1320 VLEVRHFQCP KWPNPDSPIS KTFELISVIK EEAANRDGPM IVHDEHGGVT AGTFCALTTL 1380 MHQLEKENSV DVYQVAKMIN LMRPGVFADI EQYQFLYKVI LSLVSTRQEE NPSTSLDSNG 1440 AALPDGNIAE SLESLV 1456
Seq ID NO: C315 Protein Sequence Protein Accession ft: Eos sequence
11 21 31 41 51
I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY T 1GALNQKNWG KKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSβTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNEASNSS HESRIGLAEG LESEKKAVIP 780 LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR VISTPPTPIF PISDDVGAIP 840 IKHFPKHVAD LHASSGFTEE FETLKEFYQE VQSCTVDLGI TADSSNHPDN KHKNRYINIV 900 AYDHSRVKLA QLAEKDGKLT DYINANYVDG YNRPKAYIAA QGPLKSTAED FWRMIWEHNV 960 EVIVMITNLV EKGRRKCDQY WPADGSEEYG NFLVTQKSVQ VLAYYTVRNF TLRNTKIKKG 1020 SQKGRPSGRV VTQYHYTQWP DMGVPEYSLP VLTFVRKAAY AKRHAVGPW VHCSAGVGRT 1080 GTYIVLDSML QQIQHEGTVN IFGFLKHIRS QRNYLVQTEE QYVFIHDTLV EAILSKETEV 1140 LDSHIHAYVN ALLIPGPAGK TKLEKQFQGL TLSPRLECRG TISAHCNLPL PGLTDPPTSA 1200 SRVAGTILLS QSNIQQSDYS AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS 1260 YIMGYYQSNE FIITQHPLLH TIKDFWRMIW DHNAQLWMI PDGQNMAEDE FVYWPNKDEP 1320 INCESFKVTL MAEEHKCLSN EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT 1380 FELISVIKEE AANRDGPMIV HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM 1440 RPGVFADIEQ YQFLYKVILS LVGTRQEENP STSLDSNGAA LPDGNIAESL ESLV 1494
Seq ID NO: C316 Protein Sequence Protein Accession ft: Eos sequence
11 21 31 41 51 I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG KKYPTCNSPK 60
QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120
FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180
ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300
TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360
HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPEASNSSH 420
ESRIGLAEGL ESEKKAVIPL VIVSALTFIC LWLVGILIY WRKCFQTAHF YLEDΞTSPRV 480
ISTPPTPIFP ISDDVGAIPI KHFPKHVADL HASSGFTEEF ETLKEFYQEV QSCTVDLGIT 540
ADSSNHPDNK HKNRYINIVA YDHSRVKLAQ LAEKDβKLTD YINANYVDGY NRPKAYIAAQ 600
GPLKSTAEDF WRMIWEHNVE VIVMITNLVE KGRRKCDQYW PADGSEEYGN FLVTQKSVQV 660
LAYYTVRNFT LRNTKIKKGS QKGRPSGRW TQYHYTQWPD MGVPEYSLPV LTFVRKAAYA 720
KRHAVGPVW HCSAGVGRTG TYIVLDSMLQ QIQHEGTVNI FGFLKHIRSQ RNYLVQTEEQ 780
YVFIHDTLVE AILSKETEVL DSHIHAYVNA LLIPGPAGKT KLEKQFQLLS QSNIQQSDYS 840
AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS YIMGYYQSNE FIITQHPLLH 900
TIKDFWRMIW DHNAQLWMI PDGQNMAEDE FVYWPNKDEP INCESFKVTL MAEEHKCLSN 960
EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT FELISVIKEE AANRDGPMIV 1020
HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM RPGVFADIEQ YQFLYKVILS 1080
LVSTRQEENP STSLDSNGAA LPDGNIAESL ESL 1113
Seq ID NO: C317 Protein Sequence Protein Accession #: Eos sequence
60
120
Figure imgf001358_0001
180
ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240
TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300
TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360
HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYβKY SDQLIVDMPT DNPELDLFPE 420
LIGTEEIIKE EEEGKDIEEG AIVNPβRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480
RSPTRGSEFS GKGDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540
GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600
ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSβSE ESLKDPSMEG NVWFPSSTDI 660
TAQPDVGSGR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720
TEVTPHAFIP SSRQQDLVST VNWYSQTTQ PVYNEASNSS HESRIGLAEG LESEKKAVIP 780
LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR VISTPPTPIF PISDDVGAIP 840
IKHFPKHVAD LHASSGFTEE FETLKEFYQE VQSCTVDLGI TADSSNHPDN KHKNRYINIV 900
AHDHSRVKLA QLAEKDGKLT DYINANYVDG YNRPKAYIAA QGPLKSTAED FWRMIWEHNV 960
EVIVMITNLV EKGRRKCDQY WPADGSEEYG NFLVTQKSVQ VLAYYTVRNF TLRNTKIKKG 1020
SQKGRPSGRV VTQYHYTQWP DMGVPEYSLP VLTFVRKAAY AKRHAVGPW VHCSAGVβRT 1080
GTYIVLDSML QQIQHEGTVN IFGFLKHIRS QRNYLVQTEE QYVFIHDTLV EAILSKETEV 1140
LDSHIHAYVN ALLIPGPAGK TKLEKQFQGL TLSPRLECRG TISAHCNLPL PGLTDPPTSA 1200
SRVARTILLS QSNIQQSDYS AALKQCNREK NRTSSIIPVE RSRVGISSLS GEGTDYINAS 1260
YIMGYYQSNE FIITQHPLLH TIKDFWRMIW DHNAQLWMI PDGQNMAEDE FVYWPNKDEP 1320
INCESFKVTL MAEEHKCLSN EEKLIIQDFI LEATQDDYVL EVRHFQCPKW PNPDSPISKT 1380
FELISVIKEE AANRDGPMIV HDEHGGVTAG TFCALTTLMH QLEKENSVDV YQVAKMINLM 1440
RPGVFADIEQ YQFLYKVILS LVSTRQEENP STSLDSNGAA LPDGNIAESL ESL 1493
Seq ID NO: C318 Protein Sequence Protein Accession ft : Eos sequence
11 21 31 41 51
I I I I
MRILKRFLAC IQLLCVCRLD WANGYYRQQR KLVEEIGWSY TGALNQKNWG K rKYPTCNSPK 60 QSPINIDEDL TQVNVNLKKL KFQGWDKTSL ENTFIHNTGK TVEINLTNDY RVSGGVSEMV 120 FKASKITFHW GKCNMSSDGS EHSLEGQKFP LEMQIYCFDA DRFSSFEEAV KGKGKLRALS 180 ILFEVGTEEN LDFKAIIDGV ESVSRFGKQA ALDPFILLNL LPNSTDKYYI YNGSLTSPPC 240 TDTVDWIVFK DTVSISESQL AVFCEVLTMQ QSGYVMLMDY LQNNFREQQY KFSRQVFSSY 300 TGKEEIHEAV CSSEPENVQA DPENYTSLLV TWERPRWYD TMIEKFAVLY QQLDGEDQTK 360 HEFLTDGYQD LGAILNNLLP NMSYVLQIVA ICTNGLYGKY SDQLIVDMPT DNPELDLFPE 420 LIGTEEIIKE EEEGKDIEEG AIVNPGRDSA TNQIRKKEPQ ISTTTHYNRI GTKYNEAKTN 480 RSPTRGSEFS GKβDVPNTSL NSTSQPVTKL ATEKDISLTS QTVTELPPHT VEGTSASLND 540 GSKTVLRSPH MNLSGTAESL NTVSITEYEE ESLLTSFKLD TGAEDSSGSS PATSAIPFIS 600 ENISQGYIFS SENPETITYD VLIPESARNA SEDSTSSGSE ESLKDPSMEG NVWFPSSTDI 660 TAQPDVGSβR ESFLQTNYTE IRVDESEKTT KSFSAGPVMS QGPSVTDLEM PHYSTFAYFP 720 TEVTPHAFTP SSRQQDLVST VNWYSQTTQ PVYNEASNSS HESRIGLAEG LESEKKAVIP 780 LVIVSALTFI CLWLVGILI YWRKCFQTAH FYLEDSTSPR VISTPPTPIF PISDDVGAIP 840 IKHFPKHVAD LHASSGFTEE FETLKEFYQE VQSCTVDLGI TADSSNHPDN KHKNRYINIV 900 AYDHSRVKLA QLAEKDGKLT DYINANYVDG YNRPKAYIAA QGPLKSTAED FWRMIWEHNV 960 EVIVMITNLV EKGRRKCDQY WPADGSEEYG NFLVTQKSVQ VLAYYTVRNF TLRNTKIKKG 1020 SQKGRPSGRV VTQYHYTQWP DMGVPEYSLP VLTFVRKAAY AKRHAVGPW VHCSAGVGRT 1080 GTYIVLDSML QQIQHEGTVN IFGFLKHIRS QRNYLVQTEE QYVFIHDTLV EAILSKETEV 1140 LDSHIHAYVN ALLIPGPAGK TKLEKQFQLL SQSNIQQSDY SAALKQCNRE KNRTSSIIPV 1200 ERSRVGISSL SGEβTDYINA SYIMGYYQSN EFIITQHPLL HTIKDFWRMI WDHNAQLWM 1260 IPDGQNMAED EFVYWPNKDE PINCESFKVT LMAEEHKCLS NEEKLIIQDF ILEATQAWRS 1320 DβRNFLCSDN PYAPTRKRKF RGCLPGSQDD QSDEARSLC 1359
Seq ID NO: C319 Protein Sequence Protein Accession ft: XP_002914.4
1 11 21 31 41 51
I I I I I I
MKDIDIGKEY IIPSPGYRSV RERTSTSGTH RDREDSKFRR TRPLECQDAL ETAARAEGLS 60 LDASMHSQLR ILDEEHPKGK YHHGLSALKP IRTTSKHQHP VDNAβLFSCM TFSWLSSLAR 120 VAHKKβELSM EDVWSLSKHE SSDVNCRRLE RLWQEELNEV GPDAASLRRV VWIFCRTRLI 180 LSIVCLMITQ LAGFSGPAFM VKHLLEYTQA TESNLQYSLL LVLGLLLTEI VRSWSLALTW 240
ALNYRTGVRL RGAILTMAFK KILKLKNIKE KSLGELINIC SNDGQRMFEA AAVGSLLAGG 300
PWAILGMIY NVIILGPTGF LβSAVFILFY PAMMFASRLT AYFRRKCVAA TDERVQKMNE 360
VLTYIKFIKM YAWVKAFSQS VQKIREEERR ILEKAGYFQS ITVGVAPIW VIAS-WTFSV 420
HMTLGFDLTA AQAFTWTVF NSMTFALKVT PFSVKSLSEA SVAVDRFKSL FLMEEVHMIK 480
NKPASPHIKI EMKNATLAWD SSHSSIQNSP KLTPKMKKDK RASRGKKEKV RQLQRTEHQA 540
VLAEQKGHLL LDSDERPSPE EEEGKHIHLG HLRLQRTLHS IDLEIQEGKL VβlCGSVGSβ 600
KTSLISAILG QMTLLEGSIA ISGTFAYVAQ QAWILNATLR DNILFGKEYD EERYNSVLNS 660
CCLRPDLAIL PSSDLTEIGE RGANLSGGQR QRISLARALY SDRSIYILDD PLSALDAHVβ 720
NHIFNSAIRK HLKSKTVLFV THQLQYLVDC DEVIFMKEGC ITERGTHEEL MNLNGDYATI 780
FNNLLLGETP PVEINSKKET SGSQKKSQDK βPKTβSVKKE KAVKPEEGQL VQLEEKGQGS 840
VPWSVYGVYI QAAGGPLAFL VIMALFMLNV βSTAFSTWWL SYWIKQGSGN TTVTRGNETS 900
VSDSMKDNPH MQYYASIYAL SMAVMLILKA IRGWFVKGT LRASSRLHDE LFRRILRSPM 960
KFFDTTPTGR ILNRFSKDMD EVDVRLPFQA EMFIQNVILV FFCVGMIAGV FPWFLVAVGP 1020
LVILFSVLHI VSRVLIRELK RLDNITQSPF LSHITSSIQG LATIHAYNKG QEFLHRYQEL 1080
LDDNQAPFFL FTCAMRWLAV RLDLISIALI TTTGLMIVLM HGQIPPAYAG LAISYAVQLT 1140
GLFQFTVRLA SETEARFTSV ERINHYIKTL SLEAPARIKN KAPSPDWPQE GEVTFENAEM 1200
RYRENLPLVL KKVSFTIKPK EKIGIVGRTG SGKSSLGMAL FRLVELSGGC IKIDGVRISD 1260
IGLADLRSKL SIIPQEPVLF SGTVRSNLDP FNQYTEDQIW DALERTHMKE CIAQLPLKLE 1320
SEVMENGDNF SVGERQLLCI ARALLRHCKI LILDEATAAM DTETDLLIQE TIREAFADCT 1380
MLTIAHRLHT VLGSDRIMVL AQGQWEFDT PSVLLSNDSS RFYAMFAAAE NKVAVKG 1437
Seq ID NO: C320 Protein Sequence Protein Accession ff: NP 005679.1
11 21 31 41 51
I 1 I I I
MKDIDIGKEY IIPSPGYRSV RERTSTSGTH RDREDSKFRR TRPLECQDAL ETAARAEGLS 60 LDASMHSQLR ILDEEHPKGK YHHGLSALKP IRTTSKHQHP VDNAGLFSCM TFSWLSSLAR 120 VAHKKβELSM EDVWSLSKHE SSDVNCRRLE RLWQEELNEV GPDAASLRRV VWIFCRTRLI 180 LSIVCLMITQ LAGFSGPAFM VKHLLEYTQA TESNLQYSLL LVLGLLLTEI VRSWSLALTW 240 ALNYRTGVRL RGAILTMAFK KILKLKNIKE KSLGELINIC SNDGQRMFEA AAVGSLLAGG 300 PWAILGMIY NVIILGPTGF LGSAVFILFY PAMMFASRLT AYFRRKCVAA TDERVQKMNE 360 VLTYIKFIKM YAWVKAFSQS VQKIREEERR ILEKAGYFQG ITVGVAPIW VIASWTFSV 420 HMTLGFDLTA AQAFTWTVF NSMTFALKVT PFSVKSLSEA SVAVDRFKSL FLMEEVHMIK 480 NKPASPHIKI EMKNATLAWD SSHSSIQNSP KLTPKMKKDK RASRGKKEKV RQLQRTEHQA 540 VLAEQKGHLL LDSDERPSPE EEEGKHIHLβ HLRLQRTLHS IDLEIQEGKL VGICGSVGSG 600 KTSLISAILG QMTLLEGSIA ISβTFAYVAQ QAWILNATLR DNILFGKEYD EERYNSVLNS 660 CCLRPDLAIL PSSDLTEIGE R6ANLSGGQR QRISLARALY SDRSIYILDD PLSALDAHVG 720 NHIFNSAIRK HLKSKTVLFV THQLQYLVDC DEVIFMKEGC ITERGTHEEL MNLNGDYATI 780 FNNLLLGETP PVEINSKKET SGSQKKSQDK GPKTGSVKKE KAVKPEEGQL VQLEEKGQGS 840 VPWSVYGVYI QAAGGPLAFL VIMALFMLNV βSTAFSTWWL SYWIKQGSGN TTVTRGNETS 900 VSDSMKDNPH MQYYASIYAL SMAVMLILKA IRGWFVKGT LRASSRLHDE LFRRILRSPM 960 KFFDTTPTGR ILNRFSKDMD EVDVRLPFQA EMFIQNVILV FFCVGMIAGV FPWFLVAVGP 1020 LVILFSVLHI VSRVLIRELK RLDNITQSPF LSHITSSIQG LATIHAYNKG QEFLHRYQEL 1080 LDDNQAPFFL FTCAMRWLAV RLDLISIALI TTTGLMIVLM HGQIPPAYAG LAISYAVQLT 1140 GLFQFTVRLA SETEARFTSV ERINHYIKTL SLEAPARIKN KAPSPDWPQE GEVTFENAEM 1200 RYRENLPLVL KKVSFTIKPK EKIGIVGRTG SGKSSLGMAL FRLVELSGGC IKIDGVRISD 1260 IGLADLRSKL SIIPQEPVLF SGTVRSNLDP FNQYTEDQIW DALERTHMKE CIAQLPLKLE 1320 SEVMENGDNF SVGERQLLCI ARALLRHCKI LILDEATAAM DTETDLLIQE TIREAFADCT 1380 MLTIAHRLHT VLGSDRIMVL AQGQWEFDT PSVLLSNDSS RFYAMFAAAE NKVAVKG 1437
Seq ID NO: C321 Protein Sequence Protein Accession ff: NP 005553.1
11 21 31 41 51
MPALWLGCCL CFSLLLPAAR ATSRREVCDC NGKSRQCIFD RELHRQTGNG FRCLNCNDNT 60 DGIHCEKCKN GFYRHRERDR CLPCNCNSKG SLSARCDNSG RCSCKPGVTG ARCDRCLPGF 120 HMLTDAGCTQ DQRLLDSKCD CDPAGIAGPC DAGRCVCKPA VTGERCDRCR SGYYNLDβGN 180 PEGCTQCFCY GHSASCRSSA EYSVHKITST FHQDVDGWKA VQRNGSPAKL QWSQRHQDVF 240 SSAQRLDPVY FVAPAKFLGN QQVSYGQSLS FDYRVDRGGR HPSAHDVILE GAGLRITAPL 300 MPLGKTLPCG LTKTYTFRLN EHPSNNWSPQ LSYFEYRRLL RNLTALRIRA TYGEYSTGYI 360 DNVTLISARP VSGAPAPWVE QCICPVGYKG QFCQDCASβY KRDSARLGPF GTCIPCNCQG 420 GGACDPDTGD CYSGDENPDI ECADCPIGFY NDPHDPRSCK PCPCHNGFSC SVMPETEEW 480 CNNCPPGVTG ARCELCADGY FGDPFGEHGP VRPCQPCQCN NNVDPSASGN CDRLTGRCLK 540 CIHNTAGIYC DQCKAGYFGD PLAPNPADKC RACNCNPMβS EPVGCRSDGT CVCKPGFGGP 600 NCEHGAFSCP ACYNQVKIQM DQFMQQLQRM EALISKAQGG DGWPDTELE GRMQQAEQAL 660 QDILRDAQIS EGASRSLGLQ LAKVRSQENS YQSRLDDLKM TVERVRALGS QYQNRVRDTH 720 RLITQMQLSL AESEASLGNT NIPASDHYVG PNGFKSLAQE ATRLAESHVE SASNMEQLTR 780 ETEDYSKQAL SLVRKALHEG VGSGSGSPDG AWQGLVEKL EKTKSLAQQL TREATQAEIE 840 ADRSYQHSLR LLDSVSRLQG VSDQSFQVEE AKRIKQKADS LSTLVTRHMD EFKRTQKNLG 900 NWKEEAQQLL QNGKSGREKS DQLLSRANLA KSRAQEALSM GNATFYEVES ILKNLREFDL 960 QVDNRKAEAE EAMKRLSYIS QKVSDASDKT QQAERALGSA AADAQRAKNG AGEALEISSE 1020 IEQEIGSLNL EANVTADGAL AMEKGLASLK SEMREVEGEL ERKELEFDTN MDAVQMVITE 1080 AQKVDTRAKN AGVTIQDTLN TLDGLLHLMD QPLSVDEEGL VLLEQKLSRA KTQINSQLRP 1140 MMSELEERAR QQRGHLHLLE TSIDGILADV KNLENIRDNL PPβCYNTQAL EQQ 1193
Seq ID NO: C322 Protein Sequence Protein Accession ft : NP 066924.1
1 11 21 31 41 51
I I I I I I
MANAGLQLLG FILAFLGWIG AIVSTALPQW RIYSYAβDNI VTAQAMYEGL WMSCVSQSTG QIQCKVFDSL LNLSSTLQAT RALMWβILL GVIAIFVATV GMKCMKCLED DEVQKMRMAV 120
IGGAIFLLAG LAILVATAWY GNRIVQEFYD PMTPVNARYE FGQALFTGWA AASLCLLGGA 180
LLCCSCPRKT TSYPTPRPYP KPAPSSGKDY V 211
Seq ID NO: C323 Protein Sequence Protein Accession ft: AAM77876
1 11 21 31 41 51
I I I I I I
MSSWIRWHGP AMARLWGFCW LWGFWRAAF ACPTSCKCSA SRIWCSDPSP GIVAFPRLEP 60
NSVDPENITE IFIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAHKA FLKNSNLQHI 120
NFTRNKLTSL SRKHFRHLDL SELILVGNPF TCSCDIMWIK TLQEAKSSPD TQDLYCLNES 180
SKNIPLANLQ IPNCGLPSAN LAAPNLTVEE GKSITLSCSV AGDPVPNMYW DVGNLVSKHM 240
NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH 300
WCIPFTVKGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT 360
LIAKNEYGKD EKQISAHFMG WPGIDDGANP NYPDVIYEDY GTAANDIGDT TNRSNEIPST 420
DVTDKTGREH LSVYAVWIA SWGFCLLVM LFLLKLARHS KFGMKβFVLF HKIPLDG 477
Seq ID NO: C324 Protein Sequence Protein Accession ft: NP_006171.1
1 11 21 31 41 51
I I I I I I
MSSWIRWHGP AMARLWGFCW LWGFWRAAF ACPTSCKCSA SRIWCSDPSP GIVAFPRLEP 60
NSVDPENITE IFIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAHKA FLKNSNLQHI 120
NFTRNKLTSL SRKHFRHLDL SELILVGNPF TCSCDIMWIK TLQEAKSSPD TQDLYCLNES 180
SKNIPLANLQ IPNCGLPSAN LAAPNLTVEE GKSITLSCSV AGDPVPNMYW DVGNLVSKHM 240
NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH 300
WCIPFTVKGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT 360
LIAKNEYGKD EKQISAHFMG WPGIDDGANP NYPDVIYEDY GTAANDIGDT TNRSNEIPST 420
DVTDKTGREH LSVYAVWIA SWGFCLLVM LFLLKLARHS KFGMKGPASV ISNDDDSASP 480
LHHISNβSNT PSSSEGGPDA VIIGMTKIPV IENPQYFGIT NSQLKPDTFV QHIKRHNIVL 540
KRELGEGAFG KVFLAECYNL CPEQDKILVA VKTLKDASDN ARKDFHREAE LLTNLQHEHI 600
VKFYGVCVEG DPLIMVFEYM KHGDLNKFLR AHβPDAVLMA EGNPPTELTQ SQMLHIAQQI 660
AAGMVYLASQ HFVHRDLATR NCLVGENLLV KIGDFGMSRD VYSTDYYRVG GHTMLPIRWM 720
PPESIMYRKF TTESDVWSLG WLWEIFTYG KQPWYQLSNN EVIECITQGR VLQRPRTCPQ 780
EVYELMLGCW QREPHMRKNI KGIHTLLQNL AKASPVYLDI LG 822
Seq ID NO: C325 Protein Sequence Protein Accession #: Eos sequence
1 11 21 31 41 51
I I I I I I
MSSWIRWHGP AMARLWGFCW LWGFWRAAF ACPTSCKCSA SRIWCSDPSP GIVAFPRLEP 60
NSVDPENITE IFIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAHKA FLKNSNLQHI 120
NFTRNKLTSL SRKHFRHLDL SELILVGNPF TCSCDIMWIK TLQEAKSSPD TQDLYCLNES 180
SKNIPLANLQ IPNCGLPSAN LAAPNLTVEE GKSITLSCSV AGDPVPNMYW DVGNLVSKHM 240
NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH 300
WCIPFTVKGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT 360
LIAKNEYGKD EKQISAHFMG WPGIDDGANP NYPDVIYEDY GTAANDIGDT TNRSNEIPST 420
DVTDKTGREH LSVYAVWIA SWGFCLLVM LFLLKLARHS KFGMKβFVLF HKIPLDG 477
Seq ID NO: C326 Protein Sequence Protein Accession ft: NP_570843.1
1 11 21 31 41 51
I I I I 1 I
MPLKHYLLLL VGCQAWGAGL AYHGCPSECT CSRASQVECT βARIVAVPTP LPWNAMSLQI 60
LNTHITELNE SPFLNISALI ALRIEKNELS RITPGAFRNL GSLRYLSLAN NKLQVLPIGL 120
FQGLDSLESL LLSSNQLLQI QPAHFSQCSN LKELQLHGNH LEYIPDGAFD HLVGLTKLNL 180
GKNSLTHISP RVFQHLGNLQ VLRLYENRLT DIPMGTFDGL VNLQELALQQ NQIβLLSPGL 240
FHNNHNLQRL YLSNNHISQL PPSIFMQLPQ LNRLTLFGNS LKELSLGIFG PMPNLRELWL 300
YDNHISSLPD NVFSNLRQLQ VLILSKNQIS FISPGAFNGL TELRELSLHT NALQDLDGNV 360
FRMLANLQNI SLQNNRLRQL PGNIFANVNG LMAIQLQNNQ LENLPLGIFD HLGKLCELRL 420
YDNPWRCDSD ILPLRNWLLL NQPRLGTDTV PVCFSPANVR GQSLIIINVN VAVPSVHVPE 480
VPSYPETPWY PDTPSYPDTT SVSSTTELTS PVEDYTDLTT IQVTDDRSVW GMTQAQSGLA 540
IAAIVIGIVA LACSLAACVG CCCCKKRSQA VLMQMKAPNE C 581
Seq ID NO: C327 Protein Sequence Protein Accession tt: NP 002649.1
1 11 21 31 41 51
I I I I I I
MRALLARLLL CVLWSDSKG SNELHQVPSN CDCLNGGTCV SNKYFSNIHW CNCPKKFGGQ 60
HCEIDKSKTC YEGNGHFYRG KASTDTMGRP CLPWNSATVL QQTYHAHRSD ALQLGLGKHN 120
YCRNPDNRRR PWCYVQVGLK PLVQECMVHD CADGKKPSSP PEELKFQCGQ KTLRPRFKII 180
GGEFTTIENQ PWFAAIYRRH RGGSVTYVCG GSLISPCWVI SATHCFIDYP KKEDYIVYLG 240
RSRLNSNTQG EMKFEVENLI LHKDYSADTL AHHNDIALLK IRSKEGRCAQ PSRTIQTICL 300
PSMYNDPQFG TSCEITβFβK ENSTDYLYPE QLKMTWKLI SHRECQQPHY YGSEVTTKML 360
CAADPQWKTD SCQGDSGGPL VCSLQGRMTL TGIVSWGRGC ALKDKPGVYT RVSHFLPWIR 420
SHTKEENGLA L 431
Seq ID NO: C328 Protein Sequence Protein Accession ft: XP 087254.1 1 11 21 31 41 51
1 1 | 1 I 1 | 1 | 1 1 1 MQFRECSING MKYQEINGRL VPEGPTPDSS EGNLSYLSSL SHLNNLSHLT TSSSFRTSPE 60
NETELIKEHD LFFKAVSLCH TVQISNVQTD CTGDGPWQSN LAPSQLEYYA SSPDEKALVE 120
AAARIGIVFI GNSEETMEVK TLGKLERYKL LHILEFDSDR RRMSVIVQAP SGEKLLFAKG 180
AESSILPKCI GGEIEKTRIH VDEFALKGLR TLCIAYRKFT SKEYEEIDKR IFEARTALQQ 240
REEKLAAVFQ FIEKDLILLG ATAVEDRLQD KVRETIEALR MAGIKVWVLT GDKHETAVSV 300
SLSCGHFHRT MNILELINQK SDSECAEQLR QLARRITEDH VIQHGLWDG TSLSLALREH 360
EKLFMEVCRN CSAVLCCRMA PLQKAKVIRL IKISPEKPIT LAVGDGANDV SMIQEAHVGI 420
GIMGKEGRQA ARNSDYAIAR FKFLSKLLFV HGHFYYIRIA TLVQYFFYKN VCFITPQFLY 480
QFYCLFSQQT LYDSVYLTLY NICFTSLPIL IYSLLEQHVD PHVLQNKPTL YRDISKNRLL 540
SIKTFLYWTI LGFSHAFIFF FGSYLLIGKD TSLLGNGQMF GNWTFGTLVF TVMVITVTVK 600
MALETHFWTW INHLVTWGSI IFYFVFSLFY GβlLWPFLGS QNMYFVFIQL LSSGSAWFAI 660
ILMWTCLFL DIIKKVFDRH LHPTSTEKAQ LTETNAGIKC LDSMCCFPEG EAACASVGRM 720
LERVIGRCSP THISRSWSAS DPFYTNDRSI LTLSTMDSST C 761
Seq ID NO: C329 Protein Sequence Protein Accession ff: XP 087461.1
11 21 31 41 51
MLPLLAALLA AACPLPPVRG GAADAPGLLG VPSNASVNAS SAASPSPRGC WPRRPPGPPS 60
ARARRRRRRR RRLCNISVQR QMLSSLLVRW GRPRGFQCDL LLFSTNAHGR AFFAAAFHRV 120
GPPLLIEHLG LAAGGAQQDL RLCVGCGWVR GRRTGRLRPA AAPSAAAATA GAPTALPAYP 180
AAEPPGPLWL QGEPLHFCCL DFSLEELQGE PGWRLNRKPI ESTLVACFMT LVIWWSVAA 240
LIWPVPIIAG FLPNGMEQRR TTASTTAATP AAVPAGTTAA AAAAAAAAAA AVTSGVATK 299
Seq ID NO: C330 Protein Sequence Protein Accession ft: XP 051522.2
MDLHLFDYSE P6NFSDISWP CNSSDCIWD TVMCPNMPNK SVLLYTLSFI YIFIFVIGMI 60
ANSVWWVNI QAKTTGYDTH CYILNLAIAD LWWLTIPVW WSLVQHNQW PMGELTCKVT 120
HLIFSINLFG SIFFLTCMSV DRYLSITYFT NTPSSRKKMV RRWCILVWL LAFCVSLPDT 180
YYLKTVTSAS NNETYCRSFY PEHSIKEWLI GMELVSWLG FAVPFSIIAV FYFLLARAIS 240
ASSDQEKHSS RKIIFSYWV FLVCWLPYHV AVLLDIFSIL HYIPFTCRLE HALFTALHVT 300
QCLSLVHCCV NPVLYSFINR NYRYELMKAF IFKYSAKTGL TKLIDASRVS ETEYSALEQS 360
TK 362
Seq ID NO: C331 Protein Sequence Protein Accession ft: NP 000341.1
11 21 31 41 51
I I I I I
MGFVRQIQLL LWKNWTLRKR QKIRFWELV WPLSLFLVLI WLRNANPLYS HHECHFPNKA 60
MPSAGMLPWL QGIFCNVNNP CFQSPTPGES PβlVSNYNNS ILARVYRDFQ ELLMNAPESQ 120
HLGRIWTELH ILSQFMDTLR THPERIAGRG IRIRDILKDE ETLTLFLIKN IGLSDSWYL 180
LINSQVRPEQ FAHGVPDLAL KDIACSEALL ERFIIFSQRR GAKTVRYALC SLSQGTLQWI 240
EDTLYANVDF FKLFRVLPTL LDSRSQGINL RSWGGILSDM SPRIQEFIHR PSMQDLLWVT 300
RPLMQNGGPE TFTKLMGILS DLLCGYPEGG GSRVLSFNWY EDNNYKAFLβ IDSTRKDPIY 360
SYDRRTTSFC NALIQSLESN PLTKIAWRAA KPLLMGKILY TPDSPAARRI LKNANSTFEE 420
LEHVRKLVKA WEEVGPQIWY FFDNSTQMNM IRDTLGNPTV KDFLNRQLGE EGITAEAILN 480
FLYKGPRESQ ADDMANFDWR DIFNITDRTL RLVNQYLECL VLDKFESYND ETQLTQRALS 540
LLEENMFWAG WFPDMYPWT SSLPPHVKYK IRMDIDWEK TNKIKDRYWD SGPRADPVED 600
FRYIWGGFAY LQDMVEQGIT RSQVQAEAPV GIYLQQMPYP CFVDDSFMII LNRCFPIFMV 660
LAWIYSVSMT VKSIVLEKEL RLKETLKNQG VSNAVIWCTW FLDSFSIMSM SIFLLTIFIM 720
HGRILHYSDP FILFLFLLAF STATIMLCFL LSTFFSKASL AAACSGVIYF TLYLPHILCF 780
AWQDRMTAEL KKAVSLLSPV AFGFGTEYLV RFEEQGLGLQ WSNIβNSPTE GDEFSFLLSM 840
QMMLLDAACY GLLAWYLDQV FPGDYGTPLP WYFLLQESYW LSGEGCSTRE ERALEKTEPL 900
TEETEDPEHP EGIHDSFFER EHPGWVPGVC VKNLVKIFEP CGRPAVDRLN ITFYENQITA 960
FLGHNGAGKT TTLSILTGLL PPTΞGTVLVG GRDIETSLDA VRQSLGMCPQ HNILFHHLTV 1020
AEHMLFYAQL KGKSQEEAQL EMEAMLEDTG LHHKRNEEAQ DLSGGMQRKL SVAIAFVGDA 1080
KWILDEPTS GVDPYSRRSI WDLLLKYRSG RTIIMPTHHM DEADHQGDRI AIIAQGRLYC 1140
SGTPLFLKNC FGTGLYLTLV RKMKNIQSQR KGSEGTCSCS SKGFSTTCPA HVDDLTPEQV 1200
LDGDVNELMD WLHHVPEAK LVECIGQELI FLLPNKNFKH RAYASLFREL EETLADLGLS 1260
SFGISDTPLE EIFLKVTEDS DSGPLFAGGA QQKRENVNPR HPCLGPREKA GQTPQDSNVC 1320
SPGAPAAHPE GQPPPEPECP GPQLNTGTQL VLQHVQALLV KRFQHTIRSH KDFLAQIVLP 1380
ATFVFLALML SIVILPFGEY PALTLHPWIY GQQYTFFSMD EPGSEQFTVL ADVLLNKPGF 1440
GNRCLKEGWL PEYPCGNSTP WKTPSVSPNI TQLFQKQKWT QVNPSPSCRC STREKLTMLP 1500
ECPEGAGGLP PPQRTQRSTE ILQDLTDRNI SDFLVKTYPA LIRSSLKSKF WVNEQRYGGI 1560
SIGβKLP P ITGEALVGFL SDLGRIMNVS GGPITREASK EIPDFLKHLE TEDNIKVWFN 1620
NKGWHALVSF LNVAHNAILR ASLPKDRSPE EYGITVISQP LNLTKEQLSE ITVLTTSVDA 1680
WAICVIFSM SFVPASFVLY LIQERVNKSK HLQFISGVSP TTYWVTNFLW DIMNYSVSAG 1740
LWGIFIGFQ KKAYTSPENL PALVALLLLY GWAVIPMMYP ASFLFDVPST AYVALSCANL 1800
FIGINSSAIT FILELFDNNR TLLRFNAVLR KLLIVFPHFC LGRGLIDLAL SQAVTDVYAR 1860
FβEEHSANPF HWDLIGKNLF AMWEGWYF LLTLLVQRHF FLSQWIAEPT KEPIVDEDDD 1920
VAEERQRIIT GGNKTDILRL HELTKIYLGT SSPAVDRLCV GVRPGECFGL LGVNGAGKTT 1980
TFKMLTGDTT VTSGDATVAG KSILTNISEV HQNMGYCPQF DAIDELLTGR EHLYLYARLR 2040
GVPAEEIEKV ANWSIKSLGL TVYADCLAGT YS6GNKRKLS TAIALIβCPP LVLLDEPTTG 2100
MDPQARRMLW NVIVSIIRKG RAWLTSHSM EECEALCTRL AIMVKGAFRC MGTIQHLKSK 2160
FGDGYIVTMK IKSPKDDLLP DLNPVEQFFQ GNFPGSVQRE RHYNMLQFQV SSSSLARIFQ 2220
LLLSHKDSLL IEEYSVTQTT LDQVFVNFAK QQTESHDLPL HPRAAGASRQ AQD 2273 Seq ID NO: C332 Protein Sequence Protein Accession ft: NP_006662.2
1 11 21 31 41 51
I I I I I I
MVPHAILARG RDVCRRNGLL ILSVLSVIVG CLLGFFLRTR RLSPQEISYP QFPGELLMRM 60
LKMMILPLW SSLMSGLASL DAKTSSRLGV LTVAYYLWTT FMAVIVGIFM VSIIHPGSAA 120
QKETTEQSGK PIMSSADALL DLIRNMFPAN LVEATFKQYR TKTTPWKSP KVAPEEAPPR 180 0 RILIYGVQEE NGSHVQNFAL DLTPPPEWY KSEPGTSDGM NVLGIVFFSA TMGIMLGRMG 240
DSGAPLVSFC QCLNESVMKI VAVAVWYFPF GIVFLIAGKI LEMDDPRAVG KKLGFYSVTV 300
VCGLVLHGLF ILPLLYFFIT KKNPIVFIRG ILQALLIALA TSSSSATLPI TFKCLLENNH 360
IDRRIARFVL PVGATINMDG TALYEAVAAI FIAQVNNYEL DFGQIITISI TATAASIGAA 420
GIPQAGLVTM VIVLTSVGLP TDDITLIIAV DWALDRFRTM INVLGDALAA GIMAHICRKD 480 5 FARDTGTEKL LPCETKPVSL QEIVAAQQNG CVKSVAEASE LTLGPTCPHH VPVQVERDEE 540
LPAASLNHCT IQISELETNV 560
Seq ID NO: C333 Protein Sequence Protein Accession ft: NP_005680.1 0
1 11 21 31 41 51
I I I I I I
MVTVGNYCEA EGPVGPAWMQ DGLSPCFFFT LVPSTRMALG TLALVLALPC RRRERPAGAD 60
SLSWGAGPRI SPYVLQLLLA TLQAALPLAG LAGRVGTARG APLPSYLLLA SVLESLAGAC 120 5 GLWLLWERS QARQRLAMGI WIKFRHSPβL LLLWTVAFAA ENLALVSWNS PQWWWARADL 180 βQQVQFSLWV LRYWSβGLF VLGLWAPGLR PQSYTLQVHE EDQDVERSQV RSAAQQSTWR 240
DFGRKLRLLS GYLWPRGSPA LQL LICLβ LMGLERALNV LVPIFYRNIV NLLTEKAPWN 300
SLAWTVTSYV FLKFLQGGGT GSTGFVSNLR TFLWIRVQQF TSRRVELLIF SHLHELSLRW 360
HLGRRTβEVL RIADRGTSSV TGLLSYLVFN VIPTLADIII GIIYFSMFFN AWFGLIVFLC 420 0 MSLYLTLTIV VTEWRTKFRR AMNTQENATR ARAVDSLLNF ETVKYYNAES YEVERYREAI 480
IKYQGLEWKS SASLVLLNQT QNLVIGLGLL AGSLLCAYFV TEQKLQVGDY VLFGTYIIQL 540
YMPLNWFGTY YRMIQTNFID MENMFDLLKE ETEVKDLPGA GPLRFQKβRI EFENVHFSYA 600
DGRETLQDVS FTVMPGQTLA LVGPSGAGKS TILRLLFRFY DISSβCIRID CQDISQVTQA 660
SLRSHIβ P QDTVLFNDTI ADNIRYβRVT AβNDEVEAAA QAAGIHDAIM AFPEGYRTQV 720 5 GERGLKLSGG EKQRVAIART ILKAPGIILL DEATSALDTS NERAIQASLA KVCANRTTIV 780
VAHRLSTWN ADQILVIKDG CIVERGRHEA LLSRββVYAD MWQLQQGQEE TSEDTKPQTM 840
ER 842
Seq ID NO: C334 Protein Sequence 0 Protein Accession ft: NP_000667.1
1 11 21 31 41 51
I I I I I I
MLLETQDALY VALELVIAAL SVAGNVLVCA AVGTANTLQT PTNYFLVSLA AADVAVGLFA 60 5 IPFAITISLG FCTDFYGCLF LACFVLVLTQ SSIFSLLAVA VDRYLAICVP LRYKSLVTGT 120
RARGVIAVLW VLAFGIGLTP FLGWNSKDSA TNNCTEPWDG TTNESCCLVK CLFENWPMS 180
YMVYFNFFGC VLPPLLIMLV IYIKIFLVAC RQLQRTELMD HSRTTLQREI HAAKSLAMIV 240
GIFALCWLPV HAVNCVTLFQ PAQGKNKPKW AMNMAILLSH ANSWNPIVY AYRNRDFRYT 300
FHKIISRYLL CQADVKSGNG QAGVQPALGV GL 332 0
Seq ID NO: C335 Protein Sequence Protein Accession ft: NP 443164
__ 1 11 21 31 41 51 5 i i i i i i
MGLGARGAWA ALLLGTLQVL ALLGAAHESA AMAETLQHVP SDHTNETSNS TVKPPTSVAS 60
DSSNTTVTTM KPTAASNTTT PGMVSTNMTS TTLKSTPKTT SVSQNTSQIS TSTMTVTHNS 120
SVTSAASSVT ITTTMHSEAK KGSKFDTGSF VGGIVLTLGV LSILYIGCKM YYSRRGIRYR 180
TIDEHDAII 189 0
Seq ID NO: C336 Protein Sequence Protein Accession ff : NP 004186.1
-_ 1 11 21 31 41 51
65 i i i i i i
MAQHGAMGAF RALCGLALLC ALSLGQRPTG GPGCGPGRLL LGTGTDARCC RVHTTRCCRD 60
YPGEECCSEW DCMCVQPEFH CGDPCCTTCR HHPCPPGQGV QSQGKFSFGF QCIDCASGTF 120
SGGHEGHCKP WTDCTQFGFL TVFPGNKTHN AVCVPGSPPA EPLGWLT L LAVAACVLLL 180
TSAQLGLHIW QLRSQCMWPR ETQLLLEVPP STEDARSCQF PEEERGERSA EEKGRLGDLW 240
70 V 241
Seq ID NO: C337 Protein Sequence Protein Accession ft: BAC03767.1
75 1 11 21 31 41 51
I I I I I I
MGCDGRVSGL LRRNLQPTLT YWSVFFSFGL CIAFLGPTLL DLRCQTHSSL PQISWVFFSQ 60
QLCLLLGSAL GGVFKRTLAQ SLWALFTSSL AISLVFAVIP FCRDVKVLAS VMALAGLAMG 120
CIDTVANMQL VRMYQKDSAV FLQVLHFFVG FβALLSPLIA DPFLSEANCL PANSTANTTS 180
80 RGHLFHVSRV LGQHHVDAKP WSNQTFPGLT PKDGAGTRVS YAFWIMALID LPVPMAVLML 240
LSKERLLTCC PQRRPLLLSA DELALETQPP EKEDASSLPP KFQSHLGHED LFSCCQRKNL 300
RGAPYSFFAI HITGALVLFM TDGLTGAYSA FVYSYAVEKP LSVGHKVAGY LPSLFWGFIT 360
LGRLLSIPIS SRMKPATMVF INWGVWTF LVLLIFSYNV VFLFVGTASL GLFLSSTFPS 420
MLAYTEDSLQ YKGCATTVLV TGAβVβEMVL QMLVGSIFQA QGSYSFLVCG VIFGCLAFTF 480 YILLLFFHRM HPGLPSVPTQ DRSIGMENSE CYQR 514
Seq ID NO: C338 Protein Sequence Protein Accession ft: NP_002194.1
1 11 21 31 41 51
I I I I 1 I
MGPERTGAAP LPLLLVLALS QGILNCCLAY NVGLPEAKIF SGPSSEQFGY AVQQFINPKG 60
NWLLVGSPWS GFPENRMGDV YKCPVDLSTA TCEKLNLQTS TSIPNVTEMK TNMSLGLILT 120
RNMGTGGFLT CGPLWAQQCG NQYYTTGVCS DISPDFQLSA SFSPATQPCP SLIDW CD 180
ESNSIYPWDA VKNFLEKFVQ GLDIGPTKTQ VGLIQYANNP RWFNLNTYK TKEEMIVATS 240
QTSQYGGDLT NTFGAIQYAR KYAYSAASGG RRSATKVMW VTDGESHDGS MLKAVIDQCN 300
HDNILRFGIA VLGYLNRNAL DTKNLIKEIK AIASIPTERY FFNVSDEAAL LEKAGTLGEQ 360
IFSIEβTVQG GDNFQMEMSQ VGFSADYSSQ NDILMLGAVG AFGWSβTIVQ KTSHGHLIFP 420
KQAFDQILQD RNHSSYLGYS VAAISTGEST HFVAGAPRAN YTCQIVLYSV NENGNITVIQ 480
AHRGDQIGSY FGSVLCSVDV DKDTITDVLL VGAPMYMSDL KKEEGRVYLF TIKKGILGQH 540
QFLEGPEGIE NTRFGSAIAA LSDINMDGFN DVIVGSPLEN QNSGAVYIYN βHQGTIRTKY 600
SQKILGSDGA FRSHLQYFGR SLDGYGDLNG DSITDVSIGA FGQWQLWSQ SIADVAIEAS 660
FTPEKITLVN KNAQIILKLC FSAKFRPTKQ NNQVAIVYNI TLDADGFSSR VTSRGLFKEN 720
NERCLQKNMV VNQAQSCPEH IIYIQEPSDV VNSLDLRVDI SLENPGTSPA LEAYSETAKV 780
FSIPFHKDCG EDGLCISDLV LDVRQIPAAQ EQPFIVSNQN KRLTFSVTLK NKRESAYNTG 840
IWDFSENLF FASFSLPVDG TEVTCQVAAS QKSVACDVGY PALKREQQVT FTINFDFNLQ 900
NLQNQASLSF QALSESQEEN KADNLVNLKI PLLYDAEIHL TRSTNINFYE ISSDGNVPSI 960
VHSFEDVGPK FIFSLKVTTG SVPVSMATVI IHIPQYTKEK NPLMYLTGVQ TDKAGDISCN 1020
ADINPLKIGQ TSSSVSFKSE NFRHTKELNC RTASCSNVTC WLKDVHMKGE YFVNVTTRIW 1080
NGTFASSTFQ TVQLTAAAEI NTYNPEIYVI EDNTVTIPLM IMKPDEKAEV PTGVIIGSII 1140
AGILLLLALV AILWKLGFFK RKYEKMTKNP DEIDETTELS S 1181
Seq ID NO: C339 Protein Sequence Protein Accession ft: NP 113648.1
1 11 21 31 41 51
I I I I I I
MYRPRARAAP EGRVRGCAVP STVLLLLAYL AYLALGTGVF WTLEGRAAQD SSRSFQRDKW 60
ELLQNFTCLD RPALDSLIRD WQAYKNGAS LLSNTTSMGR WELVGSFFFS VSTITTIGYG 120
NLSPNTMAAR LFCIFFALVG IPLNLWLNR LGHLMQQGVN HWASRLGGTW QDPDKARWLA 180
GSGALLSGLL LFLLLPPLLF SHMEGWSYTE GFYFAFITLS TVGFGDYVIG MNPSQRYPLW 240
YKNMVSLWIL FGMAWLALII KLILSQLETP GRVCSCCHHS SKEDFKSQSW RQGPDREPES 300
HSPQQGCYPE GPMGIIQHLE PSAHAAGCGK DS 332 Seq ID NO: C340 Protein Sequence Protein Accession #: NP 004145.1
1 11 21 31 41 51
1 I I I I I
MEWDNGTCQA LGLPPTTCVY RENFKQLLLP PVYSAVLAAG LPLNICVITQ ICTSRRALTR 60
TAVYTLNLAL ADLLYACSLP LLIYNYAQGD HWPFGDFACR LVRFLFYANL HGSILFLTCI 120
SFQRYLGICH PLAPWHKRGG RRAAWLVCVA VWLAVTTQCL PTAIFAATGI QRNRTVCYDL 180
SPPALATHYM PYGMALTVIG FLLPFAALLA CYCLLACRLC RQDGPAEPVA QERRGKAARM 240
AVWAAAFAI SFLPFHITKT AYLAVRSTPG VPCTVLEAFA AAYKGTRPFA SANSVLDPIL 300
FYFTQKKFRR RPHELLQKLT AKWQRQGR 328
Seq ID NO: C341 Protein Sequence Protein Accession ft: NP_009128.1
1 11 21 31 41 51
I I I I I I
MQRPGPRLWL VLQVMGSCAA ISSMDMERPG DGKCQPIEIP MCKDIGYNMT RMPNLMGHEN 60
QREAAIQLHE FAPLVEYGCH GHLRFFLCSL YAPMCTEQVS TPIPACRVMC EQARLKCSPI 120
MEQFNFKWPD SLDCRKLPNK NDPNYLCMEA PNNGSDEPTR GSGLFPPLFR PQRPHSAQEH 180
PLKDGGPGRG GCDNPGKFHH VEKSASCAPL CTPGVDVYWS REDKRFAWW LAIWAVLCFF 240
SSAFTVLTFL IDPARFRYPE RPIIFLSMCY CVYSVGYLIR LFAGAESIAC DRDSGQLYVI 300
QEGLESTGCT LVFLVLYYFG MASSLWWWL TLTWFLAAGK KWGHEAIEAN SSYFHLAAWA 360
IPAVKTILIL VMRRVAGDEL TGVCYVGSMD VNALTGFVLI PLACYLVIGT SFILSGFVAL 420
FHIRRVMKTG GENTDKLEKL MVRIGLFSVL YTVPATCVIA CYFYERLNMD YWKILAAQHK 480
CKMNNQTKTL DCLMAASIPA VEIFMVKIFM LLWGITSGM WIWTSKTLQS WQQVCSRRLK 540
KKSRRKPASV ITSGGIYKKA QHPQKTHHGK YEIPAQSPTC V 581
Seq ID NO: C342 Protein Sequence Protein Accession ff: NP_005752.1
1 11 21 31 41 51
I I I I I I
MEVSRRKAPP RPPRPAAPLP LLAYLLALAA PGRβADEPVW RSEQAIGAIA ASQEDGVFVA 60
SGSCLDQLDY SLEHSLSRLY RDQAGNCTEP VSLAPPARPR P6SSFSKLLL PYREGAAGLG 120
GLLLTGWTFD RGACEVRPLβ NLSRNSLRNG TEWSCHPQG STAGWYRAG RNNRWYLAVA 180
ATYVLPEPET ASRCNPAASD HDTAIALKDT EGRSLATQEL GRLKLCEGAG SLHFVDAFLW 240
NGSIYFPYYP YNYTSGAATG WPSMARIAQS TEVLFQGQAS LDCGHGHPDG RRLLLSSSLV 300
EALDVWAGVF SAAAGEGQER RSPTTTALCL FRMSEIQARA KRVSWDFKTA ESHCKEGDQP 360 ERVQPIASST LIHSDLTSVY GTWMNRTVL FLGTGDGQLL KVILGENLTS NCPEVIYEIK 420 EETPVFYKLV PDPVKNIYIY LTAGKEVRRI RVANCNKHKS CSECLTATDP HCGWCHSLQR 480 CTFQGDCVHS ENLENWLDIS SGAKKCPKIQ IIRSSKEKTT VTMVGSFSPR HSKCMVKNVD 540 SSRELCQNKS QPNRTCTCSI PTRATYKDVS WNVMFSFGS WNLSDRFNFT NCSSLKECPA 600 CVETGCAWCK SARRCIHPFT ACDPSDYERN QEQCPVAVEK TSGGGRPKEN KGNRTNQALQ 660 VFYIKSIEPQ KVSTLGKSNV IVTGANFTRA SNITMILKGT STCDKDVIQV SHVLNDTHMK 720 FSLPSSRKEM KDVCIQFDGG NCSSVGSLSY IALPHCSLIF PATTWISβGQ NITMMGRNFD 780 VIDNLIISHE LKGNINVSEY CVATYCGFLA PSLKSSKVRT NVTVKLRVQD TYLDCGTLQY 840 REDPRFTGYR VESEVDTELE VKIQKENDNF NISKKDIEIT LFHGENGQLN CSFENITRNQ 900 DLTTILCKIK GIKTASTIAN SSKKVRVKLG NLELYVEQES VPSTWYFLIV LPVLLVIVIF 960 AAVGVTRHKS KELSRKQSQQ LELLESELRK EIRDGFAELQ MDKLDWDSF GTVPFLDYKH 1020 FALRTFFPES GGFTHIFTED MHNRDANDKN ESLTALDALI CNKSFLVTVI HTLEKQKNFS 1080 VKDRCLFASF LTIALQTKLV YLTSILEVLT RDLMEQCSNM QPKLMLRRTE SWEKLLTNW 1140 MSVCLSGFLR ETVGEPFYLL VTTLNQKINK GPVDVITCKA LYTLNEDWLL WQVPEFSTVA 1200 LN FEKIPE NESADVCRNI SVNVLDCDTI GQAKEKIFQA FLSKNGSPYG LQLNEIGLEL 1260 QMGTRQKELL DIDSSSVILE DGITKLNTIβ HYEISNGSTI KVFKKIANFT SDVEYSDDHC 1320 HLILPDSEAF QDVQGKRHRG KHKFKVKEMY LTKLLSTKVA IHSVLEKLFR SIWSLPNSRA 1380 PFAIKYFFDF LDAQAENKKI TDPDWHIWK TNSLPLRFWV NILKNPQFVF DIKKTPHIDG 1440 CLSVIAQAFM DAFSLTEQQL GKEAPTNKLL YAKDIPTYKE EVKSYYKAIR DLPPLSSSEM 1500 EEFLTQESKK HENEFNEEVA LTEIYKYIVK YFDEILNKLE RERGLEEAQK QLLHVKVLFD 1560 EKKKCKWM 1568
Seq ID NO: C343 Protein Sequence Protein Accession ft: NP 002176.1
11 21 31 41 51
I I I I I
MTILGTTFGM VFSLLQWSG ESGYAQNGDL EDAELDDYSF SCYSQLEVNG SQHSLTCAFE 60 DPDVNTTNLE FEICGALVEV KCLNFRKLQE IYFIETKKFL LIGKSNICVK VGEKSLTCKK 120 IDLTTIVKPE APFDLSVIYR EGANDFWTF NTSHLQKKYV KVLMHDVAYR QEKDENKWTH 180 VNLSSTKLTL LQRKLQPAAM YEIKVRSIPD HYFKGFWSEW SPSYYFRTPE INNSSGEMDP 240 ILLTISILSF FSVALLVILA CVLWKKRIKP IVWPSLPDHK KTLEHLCKKP RKNLNVSFNP 300 ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP SEDVWTPES 360 FGRDSSLTCL AGNVSACDAP ILSSSRSLDC RESGKNGPHV YQDLLLSLGT TNSTLPPPFS 420 LQSGILTLNP VAQGQPILTS LβSNQEEAYV TMSSFYQNQ 459
Seq ID NO: C344 Protein Sequence Protein Accession ft: NP 002713.1
MAAARLCLSL LLLSTCVALL LQPLLGAQGA PLEPVYPGDN ATPEQMAQYA ADLRRYINML 60 TRPRYGKRHK EDTLAFSEWG SPHAAVPREL SPLDL 95
Seq ID NO: C345 Protein Sequence Protein Accession ft: NP 115934.1
1 11 21 31 41 51
I 1 I I I I
MTWRHHVRLL FTVSLALQII NLGNSYQREK HNGGREEVTK VATQKHRQSP LNWTSSHFGE 60 VTGSAEGWGP EEPLPYSRAF GEGASARPRC CRNGGTCVLG SFCVCPAHFT GRYCEHDQRR 120
SECGALEHGA WTLRACHLCR CIFGALHCLP LQTPDRCDPK DFLASHAHβP SAββAPSLLL 180
LLPCALLHRL LRPDAPAHPR SLVPSVLQRE RRPC6RPGLG HRL 223
Seq ID NO: C346 Protein Sequence Protein Accession ft: NP 006524.1
1 11 21 31 41 51
I I 1 I . I I
MARSLVCLGV IILLSAFSGP GVRGGPMPKL ADRKLCADQE CSHPISMAVA LQDYMAPDCR 60 FLTIHRGQW YVFSKLKGRG RLFWGGSVQG DYYGDLAARL GYFPSSIVRE DQTLKPGKVD 120 VKTDKWDFYC Q 131
Seq ID NO: C347 Protein Sequence Protein Accession #: Eos sequence
1 11 21 31 41 51
I I I I I I
MTQVTEKSTE HPEKTTSTTE KTTRTPEKPT LYSEKTICTK GKNTPVPEKP TENLGNTTLT 60
TETIKAPVKS TENPEKTAAV TKTIKPSVKV TGDKSLTTTS SHLNKTEVTH QVPTGSFTLI 120
TSRTKLSSIT SEATGNESHP YLNKDGSQKG IHAGQMGEND SFPAWAIVIV VLVAVILLLV 180
FLGLIFLVSY MMRTRRTLTQ NTQYNDAEDE GGPNSYPVYL MEQQNLGMGQ IPSPR 235
Seq ID NO: C348 Protein Sequence Protein Accession tf: NP 543146.1
11 21 31 41 51
I
MTQVTEKSTE HPEKTTSTTE KTTRTPEKPT LYSEKTICTK GKNTPVPEKP TENLGNTTLT 60
TETIKAPVKS TENPEKTAAV TKTIKPSVKV TGDKSLTTTS SHLNKTEVTH QVPTGSFTLI 120
TSRTKLSSIT SEATGNESHP YLNKDGSQKG IHAGQMGEND SFPAWAIVIV VLVAVILLLV 180
FLGLIFLVSY MMRTRRTLTQ NTQYNDAEDE GβPNSYPVYL MEQQNLGMGQ IPSPR 235
Seq ID NO: C349 Protein Sequence Protein Accession ft : FGENESH predicted
31 MWPRLAFCCW GLALVSGWAT FQQMSPSRNF SFRLFPETAP GAPGSIPAPP APGDEAAGSR 60
VERLGQAFRR RVRLLRELSE RLELVFLVDD SSSVGEVNFR SELMFVRKLL SDFPWPTAT 120
RVAIVTFSSK NYWPRVDYI STRRARQHKC ALLLQEIPAI SYRGGGTYTK GAFQQAAQIL 180
LHARENSTKV VFLITDGYSN GβDPRPIAAS LRDSGVEIFT FGIWQGNIRE LNDMASTPKE 240
EHCYLLHSFE EFEALARRAL HEDLPSGSFI QDDMVHCSYL CDEGKDCCDR MGSCKCGTHT 300
GHFECICEKG YYGKGLQYEC TACPSGTYKP EGSPGGISSC IPCPDENHTS PPGSTSPEDC 360
VCREGYRASG QTCELVHCPA LKPPENGYFI QNTCNNHFNA ACGVRCHP6F DLVGSSIILC 420
LPNGLWSGSE SYCRVRTCPH LRQPKHGHIS CSTREMLYKT TCLVACDEGY RLEGSDKLTC 480
QGNSQWDGPE PRCVERHCST FQMPKDVIIS PHNCGKQPAK FGTICYVSCR QGFILSGVKE 540
MLRCTTSGKW NVGVQAAVCK DVEAPQINCP KDIEAKTLEQ QDSANVTWQI PTAKDNSGEK 600
VSVHVHPAFT PPYLFPIGDV AIVYTATDLS GNQASCIFHI KVIDAEPPVI DWCRSPPPVQ 660
VSEKVHAASW DEPQFSDNSG AELVITRSHT QGDLFPQGET IVQYTATDPS GNNRTCDIHI 720
VIKGSPCEIP FTPVNGDFIC TPDNTGVNCT LTCLEGYDFT EGSTDKYYCA YEDGVWKPTY 780
TTEWPDCAKK RFANHGFKSF EMFYKAARCD DTDLMKKFSE AFETTLGKMV PSFCSDAEDI 840
DCRLEENLTK KYCLEYNYDY ENGFAIGPβG WGAANRLDYS YDDFLDTVQE TATSIGNAKS 900
SRIKRSAPLS DYKIKLIFNI TASVPLPDER NDTLEWENQQ RLLQTLETIT NKLKRTLNKD 960
PMYSFQLASE ILIADSNSLE TKKASPFCRP GSVLRGRMCV NCPLGTYYNL EHFTCESCRI 1020
GSYQDEEGQL ECKLCPSGMY TEYIHSRNIS DCKAQCKQGT YSYSGLETCE SCPLGTYQPK 1080
FGSRSCLSCP ENTSTVKRGA VNISACGVPC PEGKFSRSGL MPCHPCPRDY YQPNAGKAFC 1140
LACPFYGTTP FAGSRSITEC STSVLNITIF ββFβHLELLN CPSEVFHECF FNPCHNSGTC 1200
QQLGRGYVCL CPLβYTGLKC ETDIDECSPL PCLNNGVCKD LVGEFICECP SGYTGQRCEE 1260
NINECSSSPC LNKGICVDGV AGYRCTCVKG FVGLHCETEV NECQSNPCLN NAVCEDQVGG 1320
FLCKCPPGFL GTRCGKNVDE CLSQPCKNGA TCKDGANSFR CLCAAGFTβS HCELNINECQ 1380
SNPCRNQATC VDELNSYSCK CQPGFSGKRC ETEQSTGFNL DFEVSGIYGY VMLDGMLPSL 1440
HALTCTFWMK SSDDMNYGTP ISYAVDNGSD NTLLLTDYNG WVLYVNGREK ITNCPSVNDG 1500
RWHHIAITWT SANGIWKVYI DGKLSDGGAG LSVGLPIPGG βALVLGQEQD KKGEβFSPAE 1560
SFVGSISQLN LWDYVLSPQQ VKSLATSCPE ELSKGNVLAW PDFLSGIVGK VKIDSKSIFC 1620
SDCPRLGGSV PHLRTASEDL KPGSKVNLFC DPβFQLVGNP VQYCLNQGQW TQPLPHCERI 1680
SCGVPPPLEN GFHSADDFYA GSTVTYQCNN GYYLLGD≤RM FCTDNGSWNβ VSPSCLDVDE 1740
CAVGSDCSEH ASCLNVDGSY ICSCVPPYTG DGKNCAEPIK CKAPGNPENG HSSGEIYTVG 1800
AGVTFSCQEG YQLMβVTKIT CLESGEWNHL IPYCKAVSCG KPAIPENGCI EELAFTFGSK 1860
VTYRCNKGYT LAGDKESSCL ANSSWSHSPP VCEPVKCSSP ENINNGKYIL SGLTYLSTAS 1920
YSCDTGYSLQ GPSIIECTAS GIWDRAPPAC ΗLVFCGEPPA IKDAVITGNN FTFRNTVTYT 1980
CKEGYTLAGL DTIECLADGK WSRSDQQCLA VSCDEPPIVD HASPETAHRL FGDIAFYYCS 2040
DGYSLADNSQ LLCNAQGKWV PPEGQDMPRC lAHFCEKPPS VSYSILESVS KAKFAAGSW 2100
SFKCMEGFVL NTSAKIECMR GGQWNPSPMS IQCIPVRCGE PPSIMNGYAS GSNYSFGAMV 2160
AYSCNKGFYI KGEKKSTCEA TGQWSSPIPT CHPVSCGEPP KVENGFLEHT TGRIFESEVR 2220
YQCNPGYKSV GSPVFVCQAN RHWHSESPLM CVPLDCGKPP PIQNGFMKGE NFEVGSKVQF 2280
FCNEGYELVG DSSWTCQKSG KWNKKSNPKC MPAKCPEPPL LENQLVLKEL TTEVGWTFS 2340
CKEβHVLQGP SVLKCLPSQQ WNDSFPVCKI VLCTPPPLIS FGVPIPSSAL HFGSTVKYSC 2400
VGGFFLRGNS TTLCQPDGTW SSPLPECVPV ECPQPEEIPN GIIDVQGLAY LSTALYTCKP 2460
GFELVGNTTT LCGENGHWLG GKPTCKAIEC LKPKEILNGK FSYTDLHYGQ TVTYSCNRGF 2520
RLE6PSALTC LETGDWDVDA PSCNAIHCDS PQPIENGFVE GADYSYGAII IYSCFPGFQV 2580
AβHAMQTCEE SGWSSSIPTC MPIDCGLPPH IDFGDCTKLK DDQGYFEQED DMMEVPYVTP 2640
HPPYHLGAVA KTWENTKESP ATHSSNFLYG TMVSYTCNPG YELLGNPVLI CQEDGTWNGS 2700
APSCISIECD LPTAPENGFL RFTETSMGSA VQYSCKPGHI LAGSDLRLCL ENRKWSGASP 2760
RCEAISCKKP NPVMNGSIKG SNYTYLSTLY YECDPGYVLN GTERRTCQDD KNWDEDEPIC 2820
IPVDCSSPPV SANGQVRGDE YTFQKEIEYT CNEGFLLEGA RSRVCLANGS WSGATPDCVP 2880
VRCATPPQLA NGVTEGLDYG FMKEVTFHCH EGYILHGAPK LTCQSDGNWD AEIPLCKPVN 2940
CGPPEDLAHG FPNGFSFIHG GHIQYQCFPG YKLHGNSSRR CLSNGSWSGS SPSCLPCRCS 3000
TPVIEYGTVN GTDFDCGKAA RIQCFKGFKL LGLSEITCEA DGQWSSGFPH CEHTSCCSLP 3060
MIPNAFISET SSWKENVITY SCRSGYVIQG SSDLICTEKG VWSQPYPVCE PLSCGSPPSV 3120
ANAVATGEAH TYESEVKLRC LEGYTMDTDT DTFTCQKDGR WFPERISCSP KKCPLPENIT 3180
HILVHGDDFS VNRQVSVSCA EGYTFEGVNI SVCQLDGTWE PPFSDESCSP VSCCKPESPE 3240
HGFWGSKYT FESTIIYQCE PGYELEGNRE RVCQENRQWS GβVAICKETR CETPLEFLNG 3300
KADIENRTTG PNWYSCNRG YSLEGPSEAH CTENGTWSHP VPLCKPNPCP VPFVIPENAL 3360
LSEKEFYVDQ NVSIKCREGF LLQGHGIITC NPDETWTQTS AKCEKISCGP PAHVENAIAR 3420
GVHYQYGDMI TYSCYSGYML EGFLRSVCLE NβTWTSPPIC RAVCRFPCQN GGICQRPNAC 3480
SCPEGWMGRL CEEPICILPC LNGGRCVAPY QCDCPPGWTG SRCHTAVCQS PCLNGβKCVR 3540
PNRCHCLSSW TβHNCSR 3557
Seq ID NO: C350 Protein Sequence Protein Accession #: FGENESH predicted
1 11 21 31 41 51
I I I I I I
MRFSVSGMRT DYPRSVLAPA YVSVCLLLLC PREVIAPAGS EPWLCQPAPR CGDKIYNPLE 60 QCCYNDAIVS LSETRQCGPP CTFWPCFELC CLDSFGLTND F KLKVQGV NSQCHSSPIS 120 SKCERGRIC 129
Seq ID NO : C351 Protein Sequence Protein Accession ft : AAH35671.1
60
120
Figure imgf001365_0001
180
VAGDISGNMV DGYRDTSLLC KAAIHAGIIA DELGGQISVL QRKGISRYEG ILANβVLSRD 240
GSLSDKRFLF TSNGCSRSLS FEPDGQIRAS SSWQSVNESG DQVHWSPGQA RLQDQGPSWA 300
SGDSSNNHKP REWLEIDLGE KKKITGIRTT GSTQSNFNFY VKSFVMNFKN NNSKWKTYKG 360
IVNNEEKVFQ GNSNFRDPVQ NNFIPPIVAR YVRWPQTWH QRIALKVELI GCQITQGNDS 420
LVWRKTSQST SVSTKKEDET ITRPIPSEET STGINITTVA IPLVLLWLV FAGMGIFAAF 480
RKKKKKGSPY GSAEAQKTDC WKQIKYPFAR HQSAEFTISY DNEKEMTQKL DLITSDMAG 539 Seq ID NO: C352 Protein Sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MGFGAβQRLR PVPAPRSSAE EAARPGQLRL GIRRGEAELA KLAPSGVMVP βARGGGALAR 60
AAGRGLLALL LAVSAPLRLQ AEELGDGCGH LVTYQDSGTM TSKNYPGTYP NHTVCEKTIT 120 VPKβKRLILR LβDLDIESQT CASDYLLFTS SSDQYGPYCG SMTVPKELLL NTSEVTVRFE 180
SGSHISGRGF LLTYASSDHP DLITCLERAS HYLKTEYSKF CPAGCRDVAG DISGNMVDGY 240
RDTSLLCKAA IHAGIIADEL GGQISVLQRK GISRYEGILA NGVLSRDGSL SDKRFLFTSN 300
GCSRSLSFEP DGQIRASSSW QSVNESGDQV HWSPGQARLQ DQGPSWASGD SSNNHKPREW 360
LEIDLGEKKK ITGIRTTGST QSNFNFYVKS FVMNFKNNNS KWKTYKGIVN NEEKVFQGNS 420 NFRDPVQNNF IPPIVARYVR WPQTWHQRI ALKVELIGCQ ITQGNDSLVW RKTSQSTSVS 480
TKKEDETITR PIPSEETSTG INITTVAIPL VLLWLVFAG MGIFAAFRKK KKKGSPYGSA 540
EAQKTDCWKQ IKYPFARHQS AEFTISYDNE KEMTQKLDLI TSDMAG 586
Seq ID NO: C353 Protein Sequence Protein Accession ff : FβENESH predicted
1 11 21 31 41 51
I I I I I I
MFQRQERFLD LSSAEAVAAW ILHQHPDIIN KGDGCGHLVT YQDSβTMTSK NYPGTYPNHT 60
VCEKTITVPK GKRLILRLGD LDIESQTCAS DYLLFTSSSD QYGMQKEEET EVLCLSVAGA 120
QRVDIPVQLL PSFLEGWKGH ADARGPYCGS MTVPKELLLN TSEVTVRFES GSHISGR6FL 180
LTYASSDHPD LITCLERASH YLKTEYSKFC PAβCRDVAGD ISGNMVDGYR DTSLLCKAAI 240
HAGIIADELG GQISVLQRKG ISRYEGILAN GVLSRDGSLS DKRFLFTSNG CSRSLSFEPD 300
GQIRASSSWQ SVNESGDQVH WSPGQARLQD QGPSWASGDS SNNHKPREWL EIDLGEKKKI 360
TGIRTTGSTQ SNFNFYVKSF VMNFKNNNSK WKTYKGIVNN EEKVFQGNSN FRDPVQNNFI 420
PPIVARYVRV VPQTWHQRIA LKVELIβCQI TQGNDSLVWR KTSQSTSVST KKEDETITRP 480
IPSEETSTDA MPVQIVGDHT QMISQRENLG PDEGKIPFKG TAESMVRWF AVWNDLGML 540
FLAHTPEEDI DHYCWKQIKY PFARHQSAEF TISYDNEKEM TQKLDLITSD MADYQQPLMI 600
GTGTVTRKGS TFRPMDTDAE EAGVSTDAGG HYDCPQRAGR HEYALPLAPP EPEYATPIVE 660
RHVLRAHTFS AQSGYRVPGP QPGHKHSLSS GGFSPVAGVG AQDGDYQRPH SAQPADRGYD 720
RPKAVSALAT ESGHPDSQKP PTHPGTSDSY SAPRDCLTPL NQTAMTALL 769
Seq ID NO: C354 Protein Sequence Protein Accession ft: NP_004607.1
1 11 21 31 41 51
I I I I I I
MAGVSACIKY SMFTFNFLFW LCGILILALA IWVRVSNDSQ AIFGSEDV6S SSYVAVDILI 60
AVGAIIMILG FLGCCGAIKE SRCMLLLFFI GLLLILLLQV ATGILGAVFK SKSDRIVNET 120
LYENTKLLSA TGESEKQFQE AIIVFQEEFK CCGLVNGAAD WGNNFQHYPE LCACLDKQRP 180
CQSYNGKQVY KETCISFIKD FLAKNLIIVI GISFGLAVIE ILGLVFSMVL YCQIGNK 237
Seq ID NO: C355 Protein Sequence Protein Accession ft: NP_004608.1
1 11 21 31 41 51
I I I I I I
MCTGGCARCL GGTLIPLAFF GFLANILLFF PGGKVIDDND HLSQEIWFFG GILGSGVLMI 60
FPALVFLGLK NNDCCGCCGN EGCβKRFAMF TSTIFAWGF LGAGYSFIIS AISINKβPKC 120
LMANSTWGYP FHDGDYLNDE ALWNKCREPL NWPWNLTLF SILLWGGIQ MVLCAIQ N 180
GLLGTLCGDC QCCGCCGGDG PV 202
Seq ID NO: C356 Protein Sequence Protein Accession #: NP 002372.1
1 11 21 31 41 51
I I I I I I
MPRPAPARRL PGLLLLLWPL LLLPSAAPDP VARPGFRRLE TRGPGGSPGR RPSPAAPDGA 60
PASGTSEPGR ARGAGVCKSR PLDLVFIIDS SRSVRPLEFT KVKTFVSRII DTLDIGPADT 120
RVAWNYAST VKIEFQLQAY TDKQSLKQAV GRITPLSTGT MSGLAIQTAM DEAFTVEAGA 180
REPSSNIPKV AIIVTDGRPQ DQVNEVAARA QASGIELYAV GVDRADMASL KMMASEPLEE 240
HVFYVETYGV IEKLSSRFQE TFCALDPCVL βTHQCQHVCI SDGEGKHHCE CSQβYTLNAD 300
KKTCSALDRC ALNTHGCEHI CVNDRSGSYH CECYEGYTLN EDRKTCSAQD KCALGTHGCQ 360
HICVNDRTGS HHCECYEGYT LNADKKTCΞV RDKCALGSHG CQHICVSDGA ASYHCDCYPG 420 YTLNEDKKTC SATEEARRLV STEDACGCEA TLAFQDKVSS YLQRLNTKLD DILEKLKINE 480
YGQIHR 486
Seq ID NO: C357 Protein Sequence Protein Accession ft: NP_057723.1
1 11 21 31 41 51
I I I I I I
MARGSLRRLL RLLVLGLWLA LLRSVAGEQA PGTAPCSRGS SWSADLDKCM DCASCRARPH 60
SDFCLGCAAA PPAPFRLLWP ILGGALSLTF VLGLLSGFLV WRRCRRREKF TTPIEETGGE 120 eCPAVALIQ 129
Seq ID NO: C3S8 Protein Sequence Protein Accession ft: NP 001810.1 1 11 21 31 41 51
I I I I I I
MQPTLLLSLL GAVGLAAVNS MPVDNRNHNE GMVTRCIIEV LSNALSKSSA PPITPECRQV 60
LKTSRKDVKD KETTENENTK FEVRLLRDPA DASEAHESSS RGEAGAPGEE DIQGPTKADT 120
EKWAEGβGHS RERADEPQWS LYPSDSQVSE EVKTRHSEKS QREDEEEEEG ENYQKGERGE 180
DSSEEKHLEE PGETQNAFLN ERKQASAIKK EELVARSETH AAGHSQEKTH SREKSSQESG 240
EEAGSQENHP QESKGQPRSQ EESEEβEEDA TSEVDKRRTR PRHHHβRSRP DRSSQGGSLP 300
SEEKGHPQEE SEESNVSMAS LβEKRDHHST HYRASEEEPE YβEEIKGYPG VQAPEDLEWE 360
RYRGRGSEEY RAPRPQSEES WDEEDKRNYP SLELDKMAHG YGEESEEERG LEPGKGRHHR 420 0 GRGGEPRAYF MSDTREEKRF LGE6HHRVQE NQMDKARRHP QGAWKELDRN YLNYGEEGAP 480
GKWQQQGDLQ DTKENREEAR FQDKQYSSHH TAEKRKRLGE LFNPYYDPLQ WKSSHFERRD 540
NMNDNFLEGE EENELTLNEK NFFPEYNYDW WEKKPFSEDV NWGYEKRNLA RVPKLDLKRQ 600
YDRVAQLDQL LHYRKKSAEF PDFYDSEEPV STHQEAENEK DRADQTVLTE DEKKELENLA 660
AMDLELQKIA EKFSQRG 677 5
Seq ID NO: C359 Protem Sequence Protem Accession #: XP 093082 1
1 11 21 31 41 51 0 i i i i i i
MKLLCEGLKQ PNCVLQTLRW YRCLISSASC GALAAVLSTS QWLTELEFSE TKLEASALKL 60
LYGGLKDPNC KLQKLNLQFS LSVTAAKLPV GMVGNCSGFS βSLVQSHFGY CQDSSFKCDL 120
CKLLWPSTRV AAAKDCGSPK SFLSEGLNWA GRLEAVEEVL GLGVLVQPGD PASQGGGHCE 180
NYGSFRDLVD LEVKAEPSLR KGGMDLQRPT LQWLLCKIF SLKLFLFIAL PNSPGQVSW 240 5 QVTIPDGFVN VTVGSNVTLI CIYTTTVASR EQLSIQWSFF HKKEMEPISS PWEEGKWPDV 300
EAVKGTLDGQ QAELQIYFSQ GGQAVAIGQF KDRITGSNDP GNASITISHM QPADSGIYIC 360
DVNNPPDFLG QNQGILNVSV LVKPSKPLCS VQGRPETGHT ISLSCLSALG TPSPVYYWHK 420
LEGRDIVPVK ENFNPTTGIL VIGNLTNFEQ GYYQCTAINR LGNSSCEIDL TSSHPEVGII 480
VGALIGSLVG AAIIISWCF ARNKAKAKAK ERNSKTIAEL EPMTKINPRG ESEAMPREDA 540 0 TQLEVTLPSS IHETGPDTIQ EPDYEPKPTQ EPAPEPAPGS EPMAVPDLDI ELELEPETQS 600
ELEPEPEPEP ESEPGVWEP LSEDEKGWK A 631
Seq ID NO: C360 Protem Sequence Protem Accession #: FGENESH predicted 5
1 11 21 31 41 51
I I I I I I
MVFAFWKVFL ILSCLAGQVS WQVTIPDGF VNVTVGSNVT LICIYTTTVA SREQLSIQWS 60
FFHKKEMEPI SSPWEEGKWP DVEAVKGTLD GQQAELQIYF SQGGQAVAIG QFKDRITGSN 120 0 DPGNASITIS HMQPADSGIY ICDVNNPPDF LGQNQGILNV SVLVKPSKPL CSVQGRPETG 180
HTISLSCLSA LβTPSPVYYW HKLEGRDIVP VKENFNPTTG ILVIGNLTNF EQGYYQCTAI 240
NRLGNSSCEI DLTSSHPEVβ IIVGALIGSL VGAAIIISW CFARNKAKAK AKERNSKTIA 300
ELEPMTKINP RGESEAMPRE DATQLEVTLP SSIHETGPDT IQEPDYEPKP TQEPAPEPAP 360
GSEPMAVPDL DIELELEPET QSELEPEPEP EPESEPGV EPLSEDEKGV VKA 413 5
Seq ID NO: C361 Protem Sequence Prote Accession ft: NP 003011.1
1 11 21 31 41 51 0 I i i i i i
MVSRMVSTML SGLLFWLASG WTPAFAYSPR TPDRVSEADI QRLLHGVMEQ LGIARPRVEY 60
PAHQAMNLVG PQSIEGGAHE GLQHLGPFGN IPNIVAELTG DNIPKDFSED QGYPDPPNPC 120
PVGKTDDGCL ENTPDTAEFS REFQLHQHLF DPEHDYPGLG KWNKKLLYEK MKGβERRKRR 180
SVNPYLQGQR LDNWAKKSV PHFSDEDKDP E 211 5
Seq ID NO: C362 Protem Sequence Protein Accession ft: NP 076926.2
, - 1 11 21 31 41 51
60 i i i i i i
MTTMQGMEQA MPGAGPGVPQ LGNMAVIHSH LWKGLQEKFL KGEPKVLGW QILTALMSLS 60
MGITMMCMAS NTYGSNPISV YIGYTIWGSV MFIISGSLSI AAGIRTTKGL VRGSLGMNIT 120
SSVLAASGIL INTFSLAFYS FHHPYCNYYG NSNNCHGTMS ILMGLDGMVL LLSVLEFCIA 180
VSLSAFβCKV LCCTPGGWL ILPSHSHMAE TASPTPLNEV 220
65
Seq ID NO: C363 Prote Sequence Protein Accession tf: NP 002082.1
_- 1 11 21 31 41 51
70 i i i i i i
MRGSELPLVL LALVLCLAPR βRAVPLPAGG GTVLTKMYPR GNHWAVGHLM GKKSTGESSS 60 VSERGSLKQQ LREYIRWEEA ARNLLGLIEA KENRNHQPPQ PKALGNQQPS WDSEDSSNFK 120 DVGSKGKVGR LSAPGSQREG RNPQLNQQ 148
75 Seq ID NO: C364 Protein Sequence Prote Accession ft- NP_036393.1
1 11 21 31 41 51
80 M IDLQGRGVPS IIDRLRVLLML FIHTMAQIMAE QIEVENLSGLS TINPEKDIFW RIENGTTCLMA 60
EFAAKFIVPY DVWASNYVDL ITEQADIALT RGAEVKGRCG HSQSELQVFW VDRAYALKML 120
FVKESHNMSK GPEATWRLSK VQFVYDSSEK THFKDAVSAG KHTANSHHLS ALVTPAGKSY 180
ECQAQQTISL ASSDPQKTVT MILSAVHIQP FDIISDFVFS EEHKCPVDER EQLEETLPLI 240
LGLILGLVIM VTLAIYHVHH KMTANQVQIP RDRSQYKHMG 280 Seq ID NO: C365 Protein Sequence Protein Accession ft: NP 003217.1
51
MLGLVLALLS SSSAEEYVGL SANQCAVPAK DRVDCGYPHV TPKECNNRGC CFDΞRIPGVP 60 WCFKPLTRKT ECTF 74
10 Seq ID NO: C366 Protein Sequence Protein Accession #: NP 002984.1
1 11 21 31 41 51
1 ID4: M ISLPSSRAAR V IPβPSGSLCA L ILALLLLLTP P IGPLASAGPV S IAVLTELRCT C ILRVTLRVNP 60 KTIGKLQVFP AGPQCSKVEV VASLKNGKQV CLDPEAPFLK KVIQKILDSG NKKN 114
Seq ID NO: C367 Protein Sequence Protein Accession ft: NP 005233.2
20
60
120
25
Figure imgf001368_0001
180
MGHSRKKANI AIGISLAIWL LILLVTIPLY WKQTIFIPA LNITTCHDVL PEQLLVGDMF 240
NYFLSLAIGV FLFPAFLTAS AYVLMIRMLR SSAMDENSEK KRKRAIKLIV TVLAMYLICF 300
TPSNLLLWH YFLIKSQGQS HVYALYIVAL CLSTLNSCID PFVYYFVSHD FRDHAKNALL 360
CRSVRTVKQM QVSLTSKKHS RKSSSYSSSS TTVKTSY 397
30
Seq ID NO: C368 Protein Sequence Protein Accession ft: NP 003460.1
11 21 31 41 51
35 I I I I I
MAEAKTHWLG AALSLIPLIF LISGAEAASF QRNQLLQKEP DLRLENVQKF PSPEMIRALE 60 YIENLRQQAH KEESSPDYNP YQGVSVPLQQ KENGDESHLP ERDSLSEEDW MRIILEALRQ 120 AENEPQSAPK ENKPYALNSE KNFPMDMSDD YETQQWPERK LKHMQFPPMY EENSRDNPFK 180 RTNEIVEEQY TPQSLATLES VFQELGKLTG PNNQKRERMD EEQKLYTDDE DDIYKANNIA 240
40 YEDWGGEDW NPVEEKIESQ TQEEVRDSKE NIGKNEQIND EMKRSGQLGI QEEDLRKESK 300 DQLSDDVSKV IAYLKRLVNA AGSGRLQNGQ NGERATRLFE KPLDSQSIYQ LIEISRNLQI 360 PPEDLIEMLK TGEKPNGSVE PERELDLPVD LDDISEADLD HPDLFQNRML SKSGYPKTPG 420 RAGTEALPDG LSVEDILNLL GMESAANQKT SYFPNPYNQE KVLPRLPYGA GRSRSNQLPK 480 AAWIPHVENR QMAYENLNDK DQELGEYLAR MLVKYPEIIN SNQVKRVPGQ GSSEDDLQEE 540
45 EQIEQAIKEH LNQGSSQETD KLAPVSKRFP VGPPKNDDTP NRQYWDEDLL MKVLEYLNQE 600 KAEKGREHIA KRAMENM 617
Seq ID NO: C369 Protein Sequence Protein Accession ft: NP 112217.1
50
MPCAQRSWLA NLSWAQLLN FGALCYGRQP QPGPVRFPDR RQEHFIKGLP EYHWGPVRV 60
DASGHFLSYG LHYPITSSRR KRDLDGSEDW VYYRISHEEK DLFFNLTVNQ GFLSNSYIME 120
55 KRYGNLSHVK MMASSAPLCH LSGTVLQQGT RVGTAALSAC HGLTGFFQLP HGDFFIEPVK 180
KHPLVEGGYH PHIVYRRQKV PETKEPTCGL KDSVNISQKQ ELWREKWERH NLPSRSLSRR 240
SISKERWVET LWADTKMIE YHGSENVESY ILTIMNMVTG LFHNPSIGNA IHIVWRLIL 300
LEEEEQGLKI VHHAEKTLSS FCKWQKSINP KSDLNPVHHD VAVLLTRKDI CAGFNRPCET 360
LGLSHLSGMC QPHRSCNINE DSGLPLAFTI AHELGHSFGI QHDGKENDCE PVGRHPYIMS 420
60 RQLQYDPTPL TWSKCSEEYI TRFLDRGWGF CLDDIPKKKG LKSKVIAPGV IYDVHHQCQL 480
QYGPNATFCQ EVENVCQTLW CSVKGFCRSK LDAAADGTQC GEKKWCMAGK CITVGKKPES 540
IPGGW6RWSP WSHCSRTCGA GVQSAERLCN NPEPKFβGKY CTGERKRYRL CNVHPCRSEA 600
PTFRQMQCSE FDTVPYKNEL YHWFPIFNPA HPCELYCRPI DGQFSEKMLD AVIDGTPCFE 660
GGNSRNVCIN GICKMVGCDY EIDSNATEDR CGVCLGDGSS CQTVRKMFKQ KEGSGYVDIG 720
65 LIPKGARDIR VMEIEGAGNF LAIRSEDPEK YYLNGGFIIQ WNGNYKLAGT VFQYDRKGDL 780
EKLMATGPTN ESVWIQLLFQ VTNPGIKYEY TIQKDGLDND VEQMYFWQYG HWTECSVTCG 840
TGIRRQTAHC IKKGRGMVKA TFCDPETQPN GRQKKCHEKA CPPRWWAGEW EACSATCGPH 900
GEKKRTVLCI QTMVSDEQAL PPTDCQHLLK PKTLLSCNRD ILCPSDWTVG NWSECSVSCG 960
GGVRIRSVTC AKNHDEPCDV TRKPNSRALC GLQQCPSSRR VLKPNKGTIS NGKNPPTLKP 1020
70 VPPPTSRPRM LTTPTGPESM STSTPAISSP SPTTASKEβD LGGKQWQDSS TQPELSSRYL 1080
ISTGSTSQPI LTSQSLSIQP SEENVSSSDT GPTSEGGLVA TTTSGSGLSS SRNPITWPVT 1140
PFYNTLTKGP EMEIHSGSGE EREQPEDKDE SNPVIWTKIR VPGNDAPVES TEMPLAPPLT 1200
PDLSRESWWP PFSTVMEGLL PSQRPTTSET GTPRVEGMVT EKPANTLLPL GGDHQPEPSβ 1260
KTANRNHLKL PNNMNQTKSS EPVLTEEDAT SLITEGFLLN ASNYKQLTNG HGSAHWIVGN 1320
75 WSECSTTCGL GAYWKRVECT TQMDSDCAAI QRPDPAKRCH LRPCAGWKVG NWSKCSRNCS 1380
GGFKIREIQC VDSRDHRNLR PFHCQFLAGI PPPLSMSCNP EPCEAWQVEP WSQCSRSCGβ 1440
GVQERGVFCP GGLCDWTKRP TSTMSCNEHL CCHWATGNWD LCSTSCGGGF QKRIVQCVPS 1500
EGNKTEDQDQ CLCDHKPRPP EFKKCNQQAC KKSADLLCTK DKLSASFCQT LKAMKKCSVP 1560
TVRAECCFSC PQTHITHTQR QRRQRLLQKS KEL 1593
80
Seq ID NO: C370 Protein Sequence Protein Accession ft: NP 001053.1
11 31 I
MRQSHQLPLV GLLLFSFIPS QLCEICEVSE ENYIRLKPLL NTMIQSNYNR GTSAVNWLS 60 LKLVGIQIQT LMQKMIQQIK YNVKSRLSDV SSGELALIIL ALGVCRNAEE NLIYDYHLTD 120 KLENKFQAEI ENMEAHNGTP LTNYYQLSLD VLALCLFNGN YSTAEWNHF TPENKNYYFG 180 SQFSVDTGAM AVLALTCVKK SLINβQIKAD EGSLKNISIY TKSLVEKILS EKKENGLIGN 240 TFSTGEAMQA LFVSSDYYNE NDWNCQQTLN TVLTEISQGA FSNPNAAAQV LPALMGKTFL 300 DINKDSSCVS ASGNFNISAD EPITVTPPDS QSYISVNYSV RINETYFTNV TVLNGSVFLS 360 VMEKAQKMND TIFGFTMEER SWβPYITCIQ GLCANNNDRT YWELLSGGEP LSQGAGSYW 420 RNGENLEVRW SKY 433
10
Seq ID NO: C371 Protein Sequence Protein Accession #: NP 004582.1
, _ 1 11 21 31 41 51
15 I i I i i i
MCCTKSLLLA ALMSVLLLHL CGESEAASNF DCCLGYTDRI LHPKFIVGFT RQLANEGCDI 60 NAIIFHTKKK LSVCANPKQT WVKYIVRLLS KKVKNM 96
Seq ID NO: C372 Protein Sequence
20 Protein Accession ft: NP 037403.1
1 11 21 31 41 51
I I I I I I
MAGSPLLWGP RAGGVβLLVL LLLβLFRPPP ALCARPVKEP RGLSAASPPL AETGAPRRFR 60
25 RSVPRGEAAG AVQELARALA HLLEAERQER ARAEAQEAED QQARVLAQLL RVWGAPRNSD 120 PALGLDDDPD APAAQLARAL LRARLDPAAL AAQLVPAPVP AAALRPRPPV YDDGPAGPDA 180 EEAGDETPDV DPELLRYLLG RILAGSADSE GVAAPRRLRR AADHDVGSEL PPEGVLGALL 240 RVKRLETPAP QVPARRLLPP 260
30 Seq ID NO: C373 Protein Sequence Protein Accession ft: NP 002236.1
11 21 31 41 51
35 I I I I I
MLQSLAGSSC VRLVERHRSA WCFGFLVLGY LLYLVFGAW FSSVELPYED LLRQELRKLK 60 RRFLEEHECL SEQQLEQFLG RVLEASNYGV SVLSNASGNW NWDFTSALFF ASTVLSTTGY 120 GHTVPLSDGG KAFCIIYSVI GIPFTLLFLT AWQRITVHV TRRPVLYFHI RWGFSKQWA 180 IVHAVLLGFV TVSCFFFIPA AVFSVLEDDW NFLESFYFCF ISLSTIGLGD YVPGEGYNQK 240 FRELYKIGIT CYLLLGLIAM LWLETFCEL HELKKFRKMF YVKKDKDEDQ VHIIEHDQLS 300
40 FSSITDQAAG MKEDQKQNEP FVATQSSACV DGPANH 336
Seq ID NO: C374 Protein Sequence Protein Accession ft: NP 005463.1
45 31 41
METTNGTETW YESLHAVLKA LNATLHSNLL CRPGPGLGPD NQTEERRASL PGRDDNSYMY 60 ILFVMFLFAV TVGSLILGYT RSRKVDKRSD PYHVYIKNRV SMI 103
50 Seq ID NO: C375 Protein Sequence Protein Accession ff: NP 005236.1
11 21 31 41 51
I
55 I I I
MGRHLALLLL LLLLFQHFGD SDGSQRLEQT PLQFTHLEYN VTVQENSAAK TYVGHPVKMG 60 VYITHPAWEV RYKIVSGDSE NLFKAEEYIL GDFCFLRIRT KGGNTAILNR EVKDHYTLIV 120 KALEKNTNVE ARTKVRVQVL DTNDLRPLFS PTSYSVSLPE NTAIRTSIAR VSATDADIGT 180 NGEFYYSFKD RTDMFAIHPT SGVIVLTGRL DYLETKLYEM EILAADRGMK LYGSSGISSM 240 AKLTVHIEQA NECAPVITAV TLSPSELDRD PAYAIVTVDD CDQGANGDIA SLSIVAGDLL 300
60 QQFRTVRSFP GSKEYKVKAI GDIDWDSHPF GYNLTLQAKD KGTPPQFSSV KVIHVTSPQF 360 KAGPVKFEKD VYRAEISEFA PPNTPWMVK AIPAYSHLRY VFKRTPGKAK FSLNYNTGLI 420 SILEPVKRQQ AAHFELEVTT SDRKASTKVL VKVLGANSNP PEFTQTAYKA AFDENVPIGT 480 TIMSLSAVDP DEGENGYVTY SIANLNHVPF AIDHFTGAVS TSENLDYELM PRVYTLRIRA 540 SDWGLPYRRE VEVLATITLN NLNDNTPLFE KINCEGTIPR DLGVGEQITT VSAIDADELQ 600
65 LVQYQIEAβN ELDLFSLNPN SGVLSLKRSL MDGLGAKVSF HSLRITATDG ENFATPLYIN 660 I VAASHKLV NLQCEETGVA KMLAEKLLQA NKLHNQGEVE DIFFDSHSVN AHIPQFRSTL 720 PT6IQVKENQ PVGSSVIFMN STDLDTGFNG KLVYAVSGGN EDSCFMIDME TGMLKILSPL 780 DRETTDKYTL NITVYDLGIP QKAAWRLLHV VDANDNPP EFLQESYFVE VSEDKEVHSE 840 IIQVEATDKD LGPNGHVTYS ILTDTDTFSI DSVTGWNIA RPLDRELQHE HSLKIEARDQ 900
70 AREEPQLFST VWKVSLEDV NDNPPTFIPP NYRVKVREDL PEGTVIMWLE AHDPDLGQSG 960 QVRYSLLDHβ EGNFDVDKLS GAVRIVQQLD FEKKQVYNLT VRAKDKGKPV SLSSTCYVEV 1020 EWDVNENLH PPVFSSFVEK GTVKEDAPVG SLVMTVSAHD EDAGRDGEIR YSIRDGSGVG 1080 VFKIGEETGV IETSDRLDRE STSHYWLTVF ATDQGWPLS SFIEIYIEVE DVNDNAPQTS 1140 EPVYYPEIME NSPKDVSWQ IEAFDPDSSS NDKLMYKITS GNPQGFFSIH PKTGLITTTS 1200
75 RKLDREQQDE HILEVTVTDN GSPPKSTIAR VIVKILDEND NKPQFLQKFY KIRLPEREKP 1260 DRERNARREP LYRVIATDKD EGPNAEISYS IEDGNEHGKF FIEPKTβ S SKRFSAAGEY 1320 DILSIKAVDN GRPQKSSTTR LHIEWISKPK QSLEPISFEE SFFTFTVMES DPVAHMIGVI 1380 SVEPPGIPLW FDITGGNYDS HFDVDKGTGT IIVAKPLDAE QKSNYNLTVE ATDGTTTILT 1440 QVFIKVIDTN DHRPQFSTSK YEWIPEDTA PETEILQISA VDQDEKNKLI YTLQSSRDPL 1500
80 SLKKFRLDPA TGSLYTSEKL DHEAVSPAHL TVMVRDQDVP VKRNFARI NVSDTNDHAP 1560 WFTASSYKGR VYESAAVGSV VLQVTALDKD KGKNAEVLYS IESGNIGNIG NSFMIDPVLG 1620 SIKTAKELDR SNQAEYDLMV KATDKGSPPM SEITSVRIFV TIADNASPKF TSKEYSVELS 1680 ETVSIGSFVG MVTAHSQSSV VYEIKDGNTβ DAFDINPHSG TIITQKALDF ETLPIYTLII 1740 QGTNMAGLST NTTVLVHLQD ENDNAPVFMQ AEYTβLISES ASINSWLTD RNVPLVIRAA 1800 DADKDSNALL VYHIVEPSVH TYFAIDSSTG AIHTVLSLDY EETSIFHFTV QVHDMGTPRL 1860
FAEYAANVTV HVIDINDCPP VFAKPLYEAS LLLPTYKGVK VITVNATDAD SSAFSQLIYS 1920
ITEGNIGEKF SMDYKTGALT VQNTTQLRSR YELTVRASDG RFAGLTSVKI NVKESKESHL 1980
KFTQDVYSAV VKENSTEAET LAVITAIGSP INEPLFYHIL NPDRRFKISR TSGVLSTTGT 2040
PFDREQQEAF DVWEVIEEH KPSAVAH W KVIVEDQNDN APVFVNLPYY AWKVDTEVG 2100
HVIRYVTAVD RDSGRNGEVH YYLKEHHEHF QIGPLGEISL KKQFELDTLN KEYLVTWAK 2160
DGGNPAFSAE VIVPITVMNK AMPVFEKPFY SAEIAESIQV HSPWHVQAN SPEGLKVFYS 2220
ITDGDPFSQF TINFNTGVIN VIAPLDFEAH PAYKLSIRAT DSLTGAHAEV FVDIIVDDIN 2280
DNPPVFAQQS YAVTLSEASV IGTSWQVRA TDSDSEPNRG ISYQMFGNHS KSHDHFHVDS 2340
STGLISLLRT LDYEQSRQHT IFVRAVDGGM PTLSSDVIVT VDVTDLN6NP PLFEQQIYEA 2400
RISEHAPHGH FVTCVKAYDA DSSDIDKLQY SILSGNDHKH FVIDSATCII TLSNLHRHAL 2460
KPFYSLNLSV SDGVFRSSTQ VHVTVIGGNL HSPAFLQNEY EVELAENAPL HTLVMEVKTT 2520
DGDSβlYβHV TYHIVNDFAK DRFYINERβQ IFTLEKLDRE TPAEKVISVR LMAKDAGGKV 2580
AFCTVNVILT DDNDNAPQFR ATKYEVNI6S SAAKGTSWK SASDADEGSN ADITYAIEAD 2640
SESVKENLEI NKLSGVITTK ESLIGLENEF FTFFVRAVDN GSPSKESWL VYVKILPPEM 2700
QLPKFSEPFY TFTVSEDVPV GTEIDLIRAE HSGTVLYSLV KGNTPESNRD ESFVIDRQSG 2760
RLKLEKSLDH ETTKWYQFSI LARCTQDDHE MVASVDVSIQ VKDANDNSPV FESSPYEAFI 2820
VENLPGGSRV IQIRASDADS GTNGQVMYSL DQSQSVEVIE SFAINMETGW ITTLKELDHE 2880
KRDNYQIKW ASDHGEKIQL SSTAIVDVTV TDVNDSPPRF TAEIYKGTVS EDDPQGGVIA 2940
ILSTTDADSE EINRQVTYFI TGGDPLGQFA VETIQNEWKV YVKKPLDREK RDNYLLTITA 3000
TDGTFSSKAI VEVKVLDAND NSPVCEKTLY SDTIPEDVLP GKLIMQISAT DADIRSNAEI 3060
TYTLLGS6AE KFKLNPDTGE LKTSTPLDRE EQAVYHLLVR ATDGGGRFCQ ASIWTLEDV 3120
NDNAPEFSAD PYAITVFENT EPGTLLTRVQ ATDADAGLNR KILYSLIDSA DGQFSINELS 3180
GIIQLEKPLD RELQAVYTLS LKAVDQGLPR RLTATGTVIV SVLDINDNPP VFEYREYGAT 3240
VSEDILVGTE VLQVYAASRD IEANAEITYS IISGNEHGKF SIDSKTGAVF IIENLDYESS 3300
HEYYLTVEAT DGGTPSLSDV ATVNVNVTDI NDNTPVFSQD TYTTVISEDA VLEQSVITVM 3360
ADDADβPSNS HIHYSIIDGN QGSSFTIDPV RGEVKVTKLL DRETISGYTL TVQASDNGSP 3420
PRVNTTTVNI DVSDVNDNAP VFSRGNYSVI IQENKPVGFS VLQLWTDED SSHNGPPFFF 3480
TIVTGNDEKA FEVNPQGVLL TSSAIKRKEK DHYLLQVKVA DNGKPQLSSL TYIDIRVIEE 3540
SIYPPAILPL EIFITSSGEE YSGGVIGKIH ATDQDVYDTL TYSLDPQMDN LFSVSSTGGK 3600
LIAHKKLDIG QYLLNVSVTD GKFTTVADIT VHIRQVTQEM LNHTIAIRFA NLTPEEFVGD 3660
YWRNFQRALR NILGVRRNDI QIVSLQSSEP HPHLDVLLFV EKPGSAQIST KQLLHKINSS 3720
VTDIEEIIGV RILNVFQKLC AGLDCPWKFC DEKVSVDESV MSTHΞTARLS FVTPRHHRAA 3780
VCLCKEGRCP PVHHGCEDDP CPEGSECVSD PWEEKHTCVC PSGRFGQCPG SSSMTLTGNS 3840
YVKYRLTENE NKLEMKLTMR LRTYSTHAW MYARGTDYSI LEIHHGRLQY KFDCGSGPβl 3900
VSVQSIQVND GQWHAVALEV NGNYARLVLD QVHTASGTAP 6TLKTLNLDN YVFFGGHIRQ 3960
QGTRHGRSPQ VGNGFRβCMD SI LNGQELP LNSKPRSYAH IEESVDVSPβ CFLTATEDCA 4020
SNPCQNGGVC NPSPAGGYYC KCSALYIGTH CEISVNPCSS NPCLYGGTCV VDNGGFVCQC 4080
RGLYTGQRCQ LSPYCKDEPC KNGGTCFDSL DGAVCQCDSG FRβERCQSDI DECSGNPCLH 4140
GALCENTHGS YHCNCSHEYR GRHCEDAAPN QYVSTPWNIG LAEGIGIWF VAGIFLLVW 4200
FVLCRKMISR KKKHQAEPKD KHLGPATAFL QRPYFDSKLN KNIYSDIPPQ VPVRPISYTP 4260
SIPSDSRNNL DRNSFEGSAI PEHPEFSTFN PESVHGHRKA VAVCSVAPNL PPPPPSNSPS 4320
DSDSIQKPSW DFDYDTKWD LDPCLSKKPL EEKPSQPYSA RESLSEVQSL SSFQSESCDD 4380
NGYHWDTSDW MPSVPLPDIQ EFPNYEVIDE QTPLYSADPN AIDTDYYPGG YDIESDFPPP 4440
PEDFPAADEL PPLPPEFSNQ FESIHPPRDM PAAGSLGSSS RNRQRFNLNQ YLPNFYPLDM 4500
SEPQTKGTGE NSTCREPHAP YPPGYQRHFE APAVESMPMS VYASTASCSD VSACCEVESE 4560
VMMSDYESGD DGHFEEVTIP PLDSQQHTEV 4590
Seq ID NO: C376 Protein Sequence Protein Accession #: NP_055035.1
1 11 21 31 41 51
I I I I I I
MCYGKCARCI GHSLVGLALL CIAANILLYF PNGETKYASE NHLSRFVWFF SGIVGGGLLM 60
LLPAFVFIGL EQDDCCGCCG HENCGKRCAM LSSVLAALIG IAGSGYCVIV AALGLAEGPL 120
CLDSLGQWNY TFASTEGQYL LDTSTWSECT EPKHIVEWNV SLFSILLALG GIEFILCLIQ 180
VINGVLGβlC GFCCSHQQQY DC 202
Seq ID NO: C377 Protein Sequence Protein Accession ft: NP 003750.1
11 21 31 41 51
I I I I I
MSTENVEGKP SNLGERGRAR SSTFLRWQP MFNHSIFTSA VSPAAERIRF ILGEEDDSPA 60 PPQLFTELDE LLAVDGQEME WKETARWIKF EEKVEQGGER WSKPHVATLS LHSLFELRTC 120 MEKGSIMLDR EASSLPQLVE MIVDHQIETG LLKPELKDKV TYTLLRKHRH QTKKSNLRSL 180 ADIGKTVSSA SRMFTNPDNG SPAMTHRNLT SSSLNDISDK PEKDQLKNKF MKKLPRDAEA 240 SNVLVGEVDF LDTPFIAFVR LQQAVMLGAL TEVPVPTRFL FILLGPKGKA KSYHEIGRAI 300 ATLMSDEVFH DIAYKAKDRH DLIAGIDEFL DEVIVLPPGE WDPAIRIEPP KSLPSSDKRK 360 NMYSGGENVQ MNGDTPHDGG HGGGGHGDCE ELQRTGRFCG GLIKDIKRKA PFFASDFYDA 420 LNIQALSAIL FIYLATVTNA ITFGGLLGDA TDNMQGVLES FLGTAVSGAI FCLFAGQPLT 480 ILSSTGPVLV FERLLFNFSK DNNFDYLEFR LWIGLWSAFL CLILVATDAS FLVQYFTRFT 540 EEGFSSLISF IFIYDAFKKM IKLADYYPIN SNFKVGYNTL FΞCTCVPPDP ANISISNDTT 600 LAPEYLPTMS STDMYHNTTF DWAFLSKKEC SKYGGNLVGN NCNFVPDITL MSFILFLGTY 660 TSSMALKKFK TSPYFPTTAR KLISDFAIIL SILIFCVIDA LVGVDTPKLI VPSEFKPTSP 720 NRGWFVPPFG ENPWWVCLAA AIPALLVTIL IFMDQQITAV IVNRKEHKLK KGAGYHLDLF 780 WVAILMVICS LMALPWYVAA TVISIAHIDS LKMETETSAP GEQPKFLGVR EQRVTβTLVF 840 ILTGLSVFMA PILKFIPMPV LYGVFLYMGV ASLNGVQFMD RLKLLLMPLK HQPDFIYLRH 900 VPLRRVHLFT FLQVLCLALL WILKSTVAAI IFPVMILALV AVRKGMDYLF SQHDLSFLDD 960 VIPEKDKKKK EDEKKKKKKK GSLDSDNDDS DCPYSEKVPS IKIPMDIMEQ QPFLSDSKPS 1020 DRERSPTFLE RHTSC 1035
Seq ID NO: C378 Protein Sequence Protein Accession ft: NP_000949.1 1 11 21 31 41 51
I I I I I I
MSTPGVNSSA SLSPDRLNSP VTIPAVMFIF GWGNLVAIV VLCKSRKEQK ETTFYTLVCG 60
LAVTDLLGTL LVSPVTIATY MKGQWPGGQP LCEYSTFILL FFSLSGLSII CAMSVERYLA 120
INHAYFYSHY VDKRLAGLTL FAVYASNVLF CALPNMGLGS SRLQYPDTWC FIDWTTNVTA 180
HAAYSYMYAG FSSFLILATV LCNVLVCGAL LRMHRQFMRR TSLGTEQHHA AAAASVASRG 240
HPAASPALPR LSDFRRRRSF RRIAGAEIQM VILLIATSLV VLICSIPLW RVFVNQLYQP 300
SLEREVSKNP DLQAIRIASV NPILDPWIYI LLRKTVLSKA IEKIKCLFCR IGGSRRERSG 360
QHCSDSQRTS SAMSGHSRSF ISRELKEISS TSQTLLPDLS LPDLSENGLG GRNLLPGVPG 420
MGLAQEDTTS LRTLRISETS DSSQGQDSES VLLVDEAGGS GRAGPAPKGS SLQVTFPSET 480
LNLSEKCI 488
Seq ID NO: C379 Protein Sequence Protein Accession ft: NP_002650.1
1 11 21 31 41 51
I I I I I I
MGHPPLLPLL LLLHTCVPAS WGLRCMQCKT NGDCRVEECA LGQDLCRTTI VRLWEEGEEL 60
ELVEKSCTHS EKTNRTLSYR TGLKITSLTE WCGLDLCNQ GNSGRAVTYS RSRYLECISC 120
GSSDMSCERG RHQSLQCRSP EEQCLDWTH WIQEGEEGRP KDDRHLRGCβ YLPGCPGSNG 180
FHNNDTFHFL KCCNTTKCNE GPILELENLP QNGRQCYSCK GNSTHGCSSE ETFLIDCRGP 240
MNQCLVATGT HEPKNQSYMV RGCATASMCQ HAHLGDAFSM NHIDVSCCTK SGCNHPDLDV 300
QYRSGAAPQP GPAHLSLTIT LLMTARLWGβ TLLWT 335
Seq ID NO: C380 Protein Sequence Protein Accession ft: BAB55406.1
1 11 21 31 41 SI i i i i i I
MDFESβQVDP LASVILPPNL LENLSPEDSV LVRRAQFTFF NKTGLFQDVG PQRKTLVSYV 60
MACSIβNITI QNLKDPVQIK IKHTRTQEVH HPICAFWDLN KNKSFGGWNT SGCVAHRDSD 120
ASETVCLCNH FTHFGVLMDL PRSASQLDAR NTKVLTFISY IGCGISAIFS AATLLTYVAF 180
EKLRRDYPSK ILMNLSTALL FLNLLFLLDG WITSFNVDGL CIAVAVLLHF FLLATFTWMG 240 LEAIHMYIAL VKVFNTYIRR YILKFCIIGW GLPALWSW LASRNNNEVY GKESYGKEKG 300
DEFCWIQDPV IFYVTCAGYF GVMFFLNIAM FIWMVQICG RNGKRSNRTL REEVLRNLRS 360
WSLTFLLGM TWGFAFFAWG PLNIPFMYLF SIFNSLQGLF IFIFHCAMKE NVQKQWRRHL 420
CCGRFRLADN SDWSKTATNI IKKSSDNLGK SLSSSSIGSN STYLTSKSKS SSTTYFKRNS 480
HTDNVSYEHS FNKSGSLRQC FHGQVLVKTG PC 512
Seq ID NO: C381 Protein Sequence Protein Accession ft: NP 000565.1 1 11 21 31 41 51 i i i i i i
MTVARPSVPA ALPLLGELPR LLLLVLLCLP AVWGDCGLPP DVPNAQPALE GRTSFPEDTV 60
ITYKCEESFV KIPGEKDSVI CLKβSQWSDI EEFCNRSCEV PTRLNSASLK QPYITQNYFP 120
VGTWEYECR PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI 180
LFGATISFSC NTGYKLFGST SSFCLISGSS VQWSDPLPEC REIYCPAPPQ IDNGIIQGER 240 DHYGYRQSVT YACNKGFTMI GEHSIYCTVN NDEGEWSGPP PECRGKSLTS KVPPTVQKPT 300
TVNVPTTEVS PTSQKTTTKT TTPNAQATRS TPVSRTTKHF HETTPNKGSG TTSGTTRLLS 360
GHTCFTLTGL LGTLVTMGLL T 381
Seq ID NO: C382 Protein Sequence Protein Accession ff: Eos sequence
1 11 21 31 41 51
I I I I I I
MDTSRLGVLL SLPVLLQLAT GGSSPRSGVL LRGCPTHCHC EPDGRMLLRV DCSDLGLSEL 60
PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALTYIPKGAF TGLYSLKVLM 120
LQNNQLRHVP TEALQNLRSL QSLRLDANHI SYVPPSCFSG LHSLRHLWLD DNALTEIPVQ 180
AFRSLSALQA MTLALNKIHH IPDYAFGNLS SLWLHLHNN RIHSLGKKCF DGLHSLETLD 240
LNYNNLDEFP TAIRTLSNLK ELHFYDNPIQ FVGRSAFQHL PELRTLTLNG ASQITEFPDL 300
TGTANLESLT LTGAQISSLP QTVCNQLPNL QVLDLSYNLL EDLPSFSVCQ KLQKIDLRHN 360
EIYEIKVDTF QQLLSLRSLN LAWNKIAIIH PNAFSTLPSL IKLDLSSNLL SSFPITGLHβ 420
LTHLKLTβNH ALQSLISSEN FPELKVIEMP YAYQCCAFGV CENAYKISNQ WNKGDNSSMD 480
DLHKKDAGMF QAQDERDLED FLLDFEEDLK ALHSVQCSPS PGPFKPCEHL LDGWLIRIGV 540
WTIAVLALTC NALVTSTVFR SPLYISPIKL LIGVIAAVNM LTGVSSAVLA GVDAFTFGSF 600
ARHGAWWENG VGCHVIGFLS IFASESSVFL LTLAALERGF SVKYSAKFET KAPFSSLKVI 660
ILLCALLALT MAAVPLLGGS KYGASPLCLP LPFGEPSTMG YMVALILLNS LCFLMMTIAY 720
TKLYCNLDKG DLENIWDCSM VKHIALLLFT NCILNCPVAF LSFSSLINLT FISPEVIKFI 780
LLVWPLPAC LNPLLYILFN PHFKEDLVSL RKQTYVWTRS KHPSLMSINS DDVEKQSCDS 840
TQALVTFTSS SITYDLPPSS VPSPAYPVTE SCHLSSVAFV PCL 883
Seq ID NO: C383 Protein Sequence Protein Accession #: NP_003658.1
1 11 21 31 41 51
I I I I I I
MDTSRLGVLL SLPVLLQLAT GGSSPRSGVL LRGCPTHCHC EPDGRMLLRV DCSDLGLSEL 60
PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALTYIPKGAF TGLYSLKVLM 120
LQNNQLRHVP TEALQNLRSL QSLRLDANHI SYVPPSCFSG LHSLRHLWLD DNALTEIPVQ 180
AFRSLSALQA MTLALNKIHH IPDYAFGNLS SLWLHLHNN RIHSLGKKCF DGLHSLETLD 240
LNYNNLDEFP TAIRTLSNLK ELGFHSNNIR SIPEKAFVGN PSLITIHFYD NPIQFVGRSA 300 FQHLPELRTL TLNGASQITE FPDLTCTANL ESLTLTCAQI SSLPQTVCNQ LPNLQVLDLS 360
YNLLEDLPSF SVCQKLQKID LRHNEIYEIK VDTFQQLLSL RSLNLAWNKI AIIHPNAFST 420
LPSLIKLDLS SNLLSSFPIT GLHGLTHLKL TGNHALQSLI SSENFPELKV lEMPYAYQCC 480
AFGVCENAYK ISNQWNKGDN SSMDDLHKKD AGMFQAQDER DLEDFLLDFE EDLKALHSVQ 540
CSPSPGPFKP CEHLLDGWLI RIGVWTIAVL ALTCNALVTS TVFRSPLYIS PIKLLIGVIA 600
AVNMLTGVSS AVLAGVDAFT FGSFARHGAW WENGVGCHVI GFLSIFASES SVFLLTLAAL 660
ERGFSVKYSA KFETKAPFSS LKVIILLCAL LALTMAAVPL LGGSKYGASP LCLPLPFβEP 720
STMβYMVALI LLNSLCFLMM TIAYTKLYCN LDKGDLENIW DCSMVKHIAL LLFTNCILNC 780
PVAFLSFSSL INLTFISPEV IKFILLVWP LPACLNPLLY ILFNPHFKED LVSLRKQTYV 840 0 WTRSKHPSLM SINSDDVEKQ SCDSTQALVT FTSSSITYDL PPSSVPSPAY PVTESCHLSS 900
VAFVPCL 907
Seq ID NO: C384 Protein Sequence Protein Accession #: NP_003497.1 5
1 11 21 31 41 51
I I I I I I
MEMFTFLLTC IFLPLLRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD QSIAAVEMEH 60
FLPLANLECS PNIETFLCKA FVPTCIEQIH WPPCRKLCE KVYSDCKKLI DTFGIRWPEE 120 0 LECDRLQYCD ETVPVTFDPH TEFLGPQKKT EQVQRDIGFW CPRHLKTSGG QGYKFLGIDQ 180
CAPPCPNMYF KSDELEFAKS FIGTVSIFCL CATLFTFLTF LIDVRRFRYP ERPIIYYSVC 240
YSIVSLMYFI GFLLGDSTAC NKADEKLELG DTWLGSQNK ACTVLFMLLY FFTMAGTVWW 300
VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGTPGFLTV MLLALNKVEG DNISGVCFVG 360
LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI QHDGRNQEKL KKFMIRIGVF 420 5 SGLYLVPLVT LLGCYVYEQV NRITWEITWV SDHCRQYHIP CPYQAKAKAR PELALFMIKY 480
LMTLIVβlSA VFWVGSKKTC TEWAGFFKRN RKRDPISESR RVLQESCEFF LKHNSKVKHK 540
KKHYKPSSHK LKVISKSMGT STGATANHGT SAVAITSHDY LGQETLTEIQ TSPETSMREV 600
KADGASTPRL REQDCGEPAS PAASISRLSG EQVDGKGQAG SVSESARSEG RISPKSDITD 660
TGLAQSNNLQ VPSSSEPSSL KGSTSLLVHP VSGVRKEQGG GCHSDT 706 0
Seq ID NO: C385 Protein Sequence Protein Accession ft: NP 000573 _ 1 11 21 31 41 51 5 i i i i i i
MRIAVICFCL LGITCAIPVK QADSGSSEEK QLYNKYPDAV ATWLNPDPSQ KQNLLAPQTL 60
PSKSNESHDH MDDMDDEDDD DHVDSQDSID SNDSDDVDDT DDSHQSDESH HSDESDELVT 120
DFPTDLPATE VFTPWPTVD TYDGRGDSW YGLRSKSKKF RRPDIQYPDA TDEDITSHME 180
SEELNGAYKA IPVAQDLNAP SDWDSRGKDS YETSQLDDQS AETHSHKQSR LYKRKANDES 240 0 NEHSDVIDSQ ELSKVSREFH SHEFHSHEDM LWDPKSKEE DKHLKFRISH ELDSASSEVN 300
Seq ID NO: C386 Protein Sequence Protein Accession #: NP_002812 5 1 11 21 31 41 51
M IGAARGSPAR PIRRLPLLSVL LILPLLGGTQT AIIVFIKQPSS QIDALQGRRAL LIRCEVEAPGP 60
VHVYWLLDGA PVQDTERRFA QGSSLSFAAV DRLQDSGTFQ CVARDDVTGE EARSANASFN 120
IKWIEAGPW LKHPASEAEI QPQTQVTLRC HIDGHPRPTY QWFRDGTPLS DGQSNHTVSS 180
50 KERNLTLRPA GPEHSGLYSC CAHSAFGQAC SSQNFTLSIA DESFARWLA PQDVWARYE 240
EAMFHCQFSA QPPPSLQWLF EDETPITNRS RPPHLRRATV FANGSLLLTQ VRPRNAGIYR 300
CIGQβQRGPP IILEATLHLA EIEDMPLFEP RVFTAGSEER VTCLPPKGLP EPSVWWEHAG 360
VRLPTHGRVY QKGHELVLAN IAESDAGVYT CHAANLAGQR RQDVNITVAT VPSWLKKPQD 420
SQLEEGKPGY LDCLTQATPK PTWWYRNQM LISEDSRFEV FKNGTLRINS VEVYDGTWYR 480
55 CMSSTPAGSI EAQARVQVLE KLKFTPPPQP QQCMEFDKEA TVPCSATGRE KPTIKWERAD 540
GSSLPEWVTD NAGTLHFARV TRDDAGNYTC IASNGPQGQI RAHVQLTVAV FITFKVEPER 600
TTVYQGHTAL LQCEAQGDPK PLIQWKGKDR ILDPTKLGPR MHIFQNGSLV IHDVAPEDSG 660
RYTCIACNSC NIKHTEAPLY WDKPVPEES ECPGSPPPYK MIQTIGLSVG AAVAYIIAVL 720
GLMFYCKKRC KAKRLQKQPE GEEPEMECLN GGPLQNGQPS AEIQEEVALT SLGSGPAATN 780
60 KRHSTSDKMH FPRSSLQPIT TLGKSEFGEV FLAKAQGLEE GVAETLVLVK SLQTKDEQQQ 840
LDFRRELEMF GKLNHANVVR LLGLCREAEP HYMVLEYVDL GDLKQFLRIS KSKDEKLKSQ 900
PLSTKQKVAL CTQVALGMEH LSNNRFVHKD LAARNCLVSA QRQVKVSALG LSKDVYNSEY 960
YHFRQAWVPL RWMSPEAILE GDFSTKSDVW AFGVLMWEVF THGEMPHGGQ ADDEVLADLQ 1020
AGKARLPQPE GCPSKLYRLM QRCWALSPKD RPSFSEIASA L6DSTVDSKP 1070
65
Seq ID NO: C387 Protein Sequence Protein Accession ff: NP_002300.1
„_. 1 11 21 31 41 51
70 l i i i i i
MKVLAAGWP LLLVLHWKHG AGSPLPITPV NATCAIRHPC HNNLMNQIRS QLAQLNGSAN 60
ALFILYYTAQ GEPFPNNLDK LCGPNVTDFP PFHANGTEKA KLVELYRIW YLGTSLGNIT 120
RDQKILNPSA LSLHSKLNAT ADILRGLLSN VLCRLCSKYH VGHVDVTYβP DTS6KDVFQK 180
KKLGCQLLGK YKQIIAVLAQ AF 202
75
Seq ID NO: C388 Protein Sequence Protein Accession ft: XP 097508
-,Λ 1 11 21 31 41 51
SO I i i i i i
MGRPRLTLVC HVSIIISARD LSMNNLTELQ PGLFHHLRFL EELRLSGNHL SHIPGQAFSG 60
LYSLKILMLQ NNQLGGIPAE ALWELPSLQS LRLDANLISL VPERSFEGLS SLRHLWLDDN 120
ALTEIPVRAL NNLPALQAMT LALNRISHIP DYAFQNLTSL WLHLHNNRI QHLGTHSFEβ 180
LHNLETLDLN YNKLQEFPVA IRTLGRLQEL GFHNNNIKAI PEKAFMGNPL LQTIHFYDNP 240 IQFVGRSAFQ YLPKLHTLSL NGAMDIQEFP DLKGTTSLEI LTLTRAGIRL LPSGMCQQLP 300
RLRVLELSHN QIEELPSLHR CQKLEEIGLQ HNRIWEIGAD TFSQLSSLQA LDLSWNAIRS 360
IHPEAFSTLH SLVKLDLTDN QLTTLPLAGL GGLMHLKLKG NLALSQAFSK DSFPKLRILE 420
VPYAYQCCPY GMCASFFKAS CQWEAEDLHL DDEESSKRPL GLLARQAENH YDQDLDELQL 480
EMEDSKPHPS VQCSPTPGPF KPCEYLFESW GIRLAVWAIV LLSVLCNGLV LLTVFAGGPV 540
PLPPVKFWG AIAGANTLTG ISCGLLASVD ALTFGQFSEY GARWETGLGC RATGFLAVLG 600
SEASVLLLTL AAVQCSVSVS CVRAYGKSPS LGSVRAGVLG CLALAGLAAA LPLASVGEYG 660
ASPLCLPYAP PEGQPAALGF TVALVMMNSF CFLWAGAYI KLYCDLPRGD FEAVWDCAMV 720
RHVAWLIFAD βLLYCPVAFL SFASMLGLFP VTPEAVKSVL LWLPLPACL NPLLYLLFNP 780
HFRDDLRRLR PRAGDSGPLA YAAAGELEKS SCDSTQALVA FSDVDLILEA SEAGRPPGLE 840
TYGFPSVTLI SCQQPGAPRL EGSHCVEPEG NHFGNPQPSM DGELLLRAEG STPAGGGLSβ 900
GGGFQPSGLA FASHV 915
Seq ID NO: C389 Protein Sequence Protein Accession ft: NP_570901
1 11 21 31 41 51
M IASLVSLELβ LILLAVLWTA TIASPPAGLLS LILTSGQGALD QIEALGGLLNT LIADRVHCTNG 60
PCGKCLSVED ALGLGEPEGS GLPPGPVLEA RYVARLSAAA VLYLSNPEGT CEDTRAGLWA 120
SHADHLLALL ESPKALTPGL SWLLQRMQAR AAGQTPKTAC VDIPQLLEEA VGAGAPGSAG 180
GVLAALLDHV RSGSCFHALP SPQYFVDFVF QQHSSEVPMT LAELSALMQR LGVβREAHSD 240
HSHRHRGASS RDPVPLISSS NSSSVWDTVC LSARDVMAAY GLSEQAGVTP EAWAQLSPAL 300
LQQQLSGACT SQSRPPVQDQ LSQSERYLYG SLATLLICLC AVFGLLLLTC TGCRGVAHYI 360
LQTFLSLAVG ALTGDAVLHL TPKVLGLHTH SEEGLSPQPT WRLLAMLAGL YAFFLFENLF 420
NLLLPRDPED LEDGPCGHSS HSHGGHSHGV SLQLAPSELR QPKPPHEGSR ADLVAEESPE 480
LLNPEPRRLS PELRLLPYMI TLGDAVHNFA DGLAVGAAFA SSWKTGLATS LAVFCHELPH 540
ELGDFAALLH AGLSVRQALL LNLASALTAF AGLYVALAVG VSEESEAWIL AVATGLFLYV 600
ALCDMLPAML KVRDPRPWLL FLLHNVGLLG βWTVLLLLSL YEDDITF 648
Seq ID NO: C390 Protein Sequence Protein Accession tf: NP_061844
1 11 21 31 41 51
I I I I I I
MANASEPGGS GGGEAAALβL KLATLSLLLC VSLAGNVLFA LLIVRERSLH RAPYYLLLDL 60
CLADGLRALA CLPAVMLAAR RAAAAAGAPP GALGCKLLAF LAALFCFHAA FLLLGVGVTR 120
YLAIAHHRFY AERLAGWPCA AMLVCAAWAL ALAAAFPPVL DGGGDDEDAP CALEQRPDGA 180
PGALGFLLLL AVWGATHLV YLRLLFFIHD RRKMRPARLV PAVSHDWTFH GPGATGQAAA 240
NWTAGFGRGP TPPALVGIRP AGP6RGARRL LVLEEFKTEK RLCKMFYAVT LLFLLLWGPY 300
WASYLRVLV RPGAVPQAYL TASVWLTFAQ AGINPWCFL FNRELRDCFR AQFPCCQSPR 360
TTQATHPCDL KGIGL 375
Seq ID NO: C391 Protein Sequence Protein Accession ft: NP_005622
1 11 21 31 41 51
I I I I I I
MAAARPARGP ELPLLGLLLL LLLGDPGRGA ASSGNATGPG PRSAGGSARR SAAVTGPPPP 60
LSHCGRAAPC EPLRYNVCLG SVLPYGATST LLAGDSDSQE EAHGKLVLWS GLRNAPRCWA 120
VIQPLLCAVY MPKCENDRVE LPSRTLCQAT RGPCAIVERE RGWPDFLRCT PDRFPEGCTN 180
EVQNIKFNSS GQCEVPLVRT DNPKSWYEDV EGCβlQCQNP LFTEAEHQDM HSYIAAFGAV 240
TGLCTLFTLA TFVADWRNSN RYPAVILFYV NACFFVGSIG WLAQFMDGAR REIVCRADGT 300
MRLGEPTSNE TLSCVIIFVI VYYALMAGW WFWLTYAWH TSFKALGTTY QPLSGKTSYF 360
HLLTWSLPFV LTVAILAVAQ VDGDSVSGIC FVGYKNYRYR AGFVLAPIGL VLIVGGYFLI 420
RGVMTLFSIK SNHPGLLSEK AASKINETML RLGIFGFLAF GFVLITFSCH FYDFFNQAEW 480
ERSFRDYVLC QANVTIGLPT KQPIPDCEIK NRPSLLVEKI NLFAMFGTGI AMSTWVWTKA 540
TLLIWRRTWC RLTGQSDDEP KRIKKSKMIA KAFSKRHELL QNPGQELSFS MHTVSHDβPV 600
AβLAFDLNEP SADVSSAWAQ HVTKMVARRG AILPQDISVT PVATPVPPEE QANLWLVEAE 660
ISPELQKRLG RKKKRRKRKK EVCPLAPPPE LHPPAPAPST IPRLPQLPRQ KCLVAAGAWG 720
AGDSCRQGAW TLVSNPFCPE PSPPQDPFLP SAPAPVAWAH GRRQGLGPIH SRTNLMDTEL 780
MDADSDF 788
Seq ID NO: C392 Protein Sequence Protein Accession #: BAC04382
1 11 21 31 41 51
I I I I I I
MGARSGARGA LLLALLLCWD PRLSQAGRKR SGEVLPDSFP SAPAEPLPYF LQEPQDAYIV 60
KNKPVELRCR AFPATQIYFK CNGEWVSQND HVTQEGLDEA TLGARGGLRV REVQIEVSRQ 120
QVEELFGLED YWCQCVAWSS AGTTKSRRAY VRIAYLRKNF DQEPLGKEVP LDHEVLLQCR 180
PPEGVPVAEV EWLKNEDVID PTQDTNFLLT IDHNLIIRQA RLSDTANYTC VAKNIVAKRR 240
STTATVIVYV NGGWSSWAEW SPCSNRCGRG WQKRTRTCTN PAPLNGGAFC EGQAFQKTAC 300
TTICPVDGAW TEWSKWSACS TECAHWRSRE CMAPPPQNGG RDCSGTLLDS KNCTDGLCMQ 360
NKKTLSDPNS HLLEASGDAA LYAGLWAIF VWAILMAVG VWYRRNCRD FDTDITDSSA 420
ALTGGFHPVN FKTARPSNPQ LLHPSVPPDL TASAGIYRGP VYALQDSTDK IPMTNSPLLD 480
PLPSLKVEVY SSSTTGSGPG LADGADLLGV LPPGTYPSDF ARDTHFLHLR SASLGSQQLL 540
GLPRDPGSSV SGTFGCLGGR LSIPGTGVSL LVPNGAIPQG KFYEMYLLIN KAESTLPLSE 600
GTQTVLSPSV TCβPTGLLLC RPVILTMPHC AEVSARDWIF QLKTQAHQGH WEEWTLDEE 660
TLNTPCYCQL EPRACHILLD QLGTYVFTGE SYSRSAVKRL QLAVFAPALC TSLEYSLRVY 720
CLEDTPVALK EVLELERTLG GYLVEEPKPL MFKDSYHNLR LSLHDLPHAH WRSKLLAKYQ 780
EIPFYHIWSG SQKALHCTFT LERHSLASTE LTCKICVRQV EGEGQIFQLH TTLAETPAGS 840
LDTLCSAPGS TVTTQLGPYA FKIPLSIRQK ICNSLDAPNS RGNDWRMLAQ KLSMDRYLNY 900
FATKASPTGV ILDLWEALQQ DDGDLNSLAS ALEEMGKSEM LVAVATDGDC 950 Seq ID NO: C393 Protein Sequence Protein Accession ft: NP_004616
1 11 21 31 41 51
I I I I I I
MNRKARRCLG HLFLSLGMVY LRIGGFSSW ALGASIICNK IPGLAPRQRA ICQSRPDAII 60
VIGEGSQMGL DECQFQFRNG RWNCSALGER TVFβKELKVβ SREAAFTYAI IAAGVAHAIT 120
AACTQGNLSD CGCDKEKQGQ YHRDEGWKWG GCSADIRYGI GFAKVFVDAR EIKQNARTLM 180
NLHNNEAGRK ILEENMKLEC KCHGVSGSCT TKTCWTTLPQ FRELGYVLKD KYNEAVHVEP 240
VRASRNKRPT FLKIKKPLSY RKPMDTDLVY lEKSPNYCEE DPVTGSVGTQ GRACNKTAPQ 300
ASGCDLMCCG RGYNTHQYAR VWQCNCKFHW CCYVKCNTCS ERTEMYTCK 349
Seq ID NO : C394 Protein Sequence Protein Accession # : NP_003777
1 11 21 31 41 51
I I I I I I
MDALCGSGEL GSKFWDSNLS VHTENPDLTP CFQNSLLAWV PCIYLWVALP CYLLYLRHHC 60
RGYIILSHLS KLKMVLGVLL WCVSWADLFY SFHGLVHGRA PAPVFFVTPL GVTMLLAT 120
LLIQYERLQG VQSSGVLIIF WFLCWCAIV PFRSKILLAK AEGEISDPFR FTTFYIHFAL 180
VLSALILACF REKPPFFSAK NVDPNPYPET SAGFLSRLFF WWFTKMAIYβ YRHPLEEKDL 240
WSLKEEDRSQ MWQQLLEAW RKQEKQTARH KASAAPGKNA SGEDEVLLGA RPRPRKPSFL 300
KALLATFβSS FLISACFKLI QDLLSFINPQ LLSILIRFIS NPMAPSWWGF LVAGLMFLCS 360
MMQSLILQHY YHYIFVTGVK FRTGIMGVIY RKALVITNSV KRASTVGEIV NLMSVDAQRF 420
MDLAPFLNLL WSAPLQIILA IYFLWQNLGP SVLAGVAFMV LLIPLNGAVA VKMRAFQVKQ 480
MKLKDSRIKL MSEILNGIKV LKLYAWEPSF LKQVEGIRQG ELQLLRTAAY LHTTTTFTWM 540
CSPFLVTLIT LWVYVYVDPN NVLDAEKAFV SVSLFNILRL PLNMLPQLIS NLTQASVSLK 600
RIQQFLSQEE LDPQSVERKT ISPGYAITIH SGTFTWAQDL PPTLHSLDIQ VPKGALVA 660
GPVGCGKSSL VSALLGEMEK LEGKVHMKGS VAYVPQQAWI QNCTLQENVL FGKALNPKRY 720
QQTLEACALL ADLEMLPGGD QTEIGEKGIN LSGGQRQRVS LARAVYSDAD IFLLDDPLSA 780
VDSHVAKHIF DHVIGPEGVL AGKTRVLVTH GISFLPQTDF IIVLADGQVS EMGPYPALLQ 840
RNGSFANFLC NYAPDEDQGH LEDSWTALEG AEDKEALLIE DTLSNHTDLT DNDPVTYWQ 900
KQFMRQLSAL SSDGEGQGRP VPRRHLGPSE KVQVTEAKAD GALTQEEKAA IGTVELSVFW 960
DYAKAVGLCT TLAICLLYVG QSAAAIGANV WLSAWTNDAM ADSRQNNTSL RLGVYAALGI 1020
LQGFLVMLAA MAMAAGGIQA ARVLHQALLH NKIRSPQSFF DTTPSGRILN CFSKDIY D 1080
EVLAPVILML LNSFFNAIST LWIMASTPL FTWILPLAV LYTLVQRFYA ATSRQLKRLE 1140
SVSRSPIYSH FSETVTGASV IRAYNRSRDF EIISDTKVDA NQRSCYPYII SNRWLSIGVE 1200
FVGNCWLFA ALFAVIGRSS LNPGLVGLSV SYSLQVTFAL NWMIRMMSDL ESNIVAVERV 1260
KEYSKTETEA PWWEGSRPP EGWPPRGEVE FRNYSVRYRP GLDLVLRDLS LHVHGGEKVG 1320
IVGRTGAGKS SMTLCLFRIL EAAKGEIRID GLNVADIGLH DLRSQLTIIP QDPILFSGTL 1380
RMNLDPFGSY SEEDIWWALE LSHLHTFVSS QPAGLDFQCS EGGENLSVGQ RQLVCLARAL 1440
LRKSRILVLD EATAAIDLET DNLIQATIRT QFDTCTVLTI AHRLNTIMDY TRVLVLDKGV 1500
VAEFDSPANL IAARGIFYGM ARDAGLA 1527
Seq ID NO: C395 Protein Sequence Protein Accession #: NP 004617
1 11 21 31 41 51 I i i i i i
MRARPQVCEA LLFALALQTG VCYGIKWLAL SKTPSALALN QTQHCKQLEG LVSAQVQLCR 60
SNLELMHTW HAAREVMKAC RRAFADMRWN CSSIELAPNY LLDLERGTRE SAFVYALSAA 120
AISHAIARAC TSGDLPGCSC GPVPGEPPGP GNRWGGCADN LSYGLLMGAK FSDAPMKVKK 180
TGSQANKLMR LHNSEVGRQA LRASLEMKCK CHGVSGSCSI RTCWKGLQEL QDVAADLKTR 240
YLSATK HR PMGTRKHLVP KDLDIRPVKD SELVYLQSSP DFCMKNEKVG SHGTQDRQCN 300
KTSNGSDSCD LMCCβRGYNP YTDRWERCH CKYHWCCYVT CRRCERTVER YVCK 354
Seq ID NO: C396 Protein Sequence Protem Accession ff: NP_114072
1 11 21 31 41 51
I I I I I I
MEWGYLLEVT SLLAALALLQ RSSGAAAASA KELACQEITV PLCKGIGYNY TYMPNQFNHD 60
TQDEAGLEVH QFWPLVEIQC SPDLKFFLCS MYTPICLEDY KKPLPPCRSV CERAKAGCAP 120
LMRQYGFAWP DRMRCDRLPE QGNPDTLCMD YNRTDLTTAA PSPPRRLPPP PPGEQPPSGS 180
GHGRPPGARP PHRGGGRGGG GGDAAAPPAR GGGGGGKARP PGGGAAPCEP GCQCRAPMVS 240
VSSERHPLYN RVKTCQIANC ALPCHNPFFS QDERAFTVFW IGLWSVLCFV STFATVSTFL 300
IDMERFKYPE RPIIFLSACY LFVSVGYLVR LVAGHEKVAC SGGAPGAGGA GGAGGAAAGA 360
GAAGAGAβGP GGRGEYEELG AVEQHVRYET TGPALCTWF LLVYFFGMAS SIWWVILSLT 420
WFLAAGMKWG NEAIAGYSQY FHLAAWLVPS VKSIAVLALS SVDGDPVAGI CYVGNQSLDN 480
LRGFVLAPLV IYLFIGTMFL LAβFVSLFRI RSVIKQQDGP TKTHKLEKLM IRLGLFTVLY 540
TVPAAWVAC LFYEQHNRPR WEATHNCPCL RDLQPDQARR PDYAVFMLKY FMCLWGITS 600
GVWVWSGKTL ESWRSLCTRC CWASKGAAVβ GGAGATAAGG GGGPGGGGGG GPGGGGβPGG 660
GGGSLYSDVS TGLTWRSGTA SSVSYPKQMP LSQV 694
Seq ID NO: C397 Protein Sequence Protein Accession ff: XP 050625 1 11 21 31 41 51 i i i i i i
MLQGPGSLLL LFLASHCCLG SARGLFLFGQ PDFSYKRSNC KPIPANLQLC HGIEYQNMRL 60
PNLLGHETMK EVLEQAGAWI PLVMKQCHPD TKKFLCSLFA PVCLDDLDET IQPCHSLCVQ 120
VKDRCAPVMS AFGFPWPDML ECDRFPQDND LCIPLASSDH LLPATEEAPK VCEACKNKND 180
DDNDIMETLC KNDFALKIKV KEITYINRDT KIILETKSKT IYKLNGVSER DLKKSVLWLK 240 DSLQCTCEEM NDINAPYLVM GQKQGGELVI TSVKRWQKGQ REFKRISRSI RKLQC 295
Seq ID NO: C398 Protein Sequence Protein Accession ff : NP_001297.1
1 11 21 31 41 51
I I I I I I
MSMGLEITGT ALAVLGWLGT IVCCALPMWR VSAFIGSNII TSQNIWEGLW MNCWQSTGQ 60
MQCKVYDSLL ALPQDLQAAR ALIWAILLA AFGLLVALVG AQCTNCVQDD TAKAKITIVA 120
GVLFLLAALL TLVPVSWSAN TIIRDFYNPV VPEAQKREMG AGLYVGWAAA ALQLLGβALL 180 CCSCPPREKK YTATKWYSA PRSTGPGASL GTβYDRKDYV 220
Seq ID NO: C399 Protein Sequence Protein Accession #: NP_036581.1
1 11 21 31 41 51
I I I I I I
MESRKDITNQ EELWKMKPRR NLEEDDYLHK DTGETSMLKR PVLLHLHQTA HADEFDCPSE 60
LQHTQELFPQ WHLPIKIAAI IASLTFLYTL LREVIHPLAT SHQQYFYKIP ILVINKVLPM 120
VSITLLALVY LPGVIAAIVQ LHNGTKYKKF PHWLDKWMLT RKQFGLLSFF FAVLHAIYSL 180
SYPMRRSYRY KLLNWAYQQV QQNKEDAWIE HDVWRMEIYV SLGIVGLAIL ALLAVTSIPS 240
VSDSLTWREF HYIQSKLGIV SLLLGTIHAL IFAWNKWIDI KQFVWYTPPT FMIAVFLPIV 300
VLIFKSILFL PCLRKKILKI RHGWEDVTKI NKTEICSQL 339 Seq ID NO: C400 Protein Sequence Protein Accession ft: NP 001766.1
1 11 21 31 41 51
I I I I I I
MANCEFSPVS GDKPCCRLSR RAQLCLGVSI LVLILVWLA VPRWRQTW SGPGTTKRFP 60
ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN 120
KILLWSRIKD LAHQFTQVQR DMFTLEDTLL GYLADDLTWC GEFNTSKINY QSCPDWRKDC 180
SNNPVSVFWK TVSRRFAEAA CD HVMLNG SRSKIFDKNS TFβSVEVHNL QPEKVQTLEA 240
WVIHGGREDS RDLCQDPTIK ELESIISKRN IQFSCKNIYR PDKFLQCVKN PEDSSCTSEI 300
Seq ID NO: C401 Protein Sequence Protein Accession ft: XP 120513.2
1 11 21 31 41 51 i i i i i i
MVSCTFSGPL RETNENVKKF YALRAFMFRM SSEAAMLGES RTPKPRKHRA TTRAKIFKRF 60
FSEGSESNSR LVEELAVIHT YSDDPAPTTS PSSVQPREFG VMQGAPRARF GSRTPPAAAE 120
ASSPHLGIGE AACQSGARAA APRAGARRCQ PQRQAAAAAA TAQTHTLPHA RTRADPAGRR 180
RRHPRSPAPβ GEGTCSEGPA PRRRMEEEMQ PAEEGPSVPK IYKQRSPYSV LKTFPSKRPA 240
LAKRYERPTL VELPHGHLRT PAQPPPASPA ASSSSSFAAV VRL6APPRPP RRβFRARGTI 300
PPLLPAPGVA GTLLPPPTSS SPPSPRPRPW HAAAPRGβTS HTHMWRSQST LPβSDTMVSV 360
FβLMAQRRWQ HRSLKQFEWG ILβSWβTWPC βQDWLEKEβQ VAVLLPRSEβ NTAPKKSRMI 420
LDAFAQQCSR VLSLLNCββK LLDSNHSQSM ISCVKQEGSS YNERQEHCHI GKGVHSQTSD 480
NVDIEMQYMQ RKQQTSAFLR VFTDSLQNYL LSβSFPTPNP SSASEYβHLA DVDPLSTSPV 540
HTLENISLDS TASLCKSRHL SREPPVKSDF PNPLQQALAβ GASRPFSGAQ QSIAYRVNSE 600
LEDGIRSPVP LSCEALEMDL TSLGSKQLLN NYPVYITSKQ WDEAVNSSKK DGRRLLRYLI 660
RFVFTTDELK YSCGLGKRKR SVQSGETGPE RRPLDPVKVT CLRβTASFRS VSPSVISFHR 720
IGCGSPRTSV QPSVF 735
Seq ID NO: C402 Protein Sequence Protein Accession ft: BAA92562.1
1 11 21 31 41 51
I I I I I I
METTVLSGIN FEYKGMTGWE VAGDHIYTAA GASDNDFMIL TLWPGFRPP QSVMADTENK 60
EVARITFVFE TLCSVNCELY FMVGVNSRTN TPVETWKGSK GKQSYTYIIE ENTTTSFTWA 120
FQRTTFHEAS RKYTNDVAKI YSINVTNVMN GVASYCRPCA LEASDVGSSC TSCPAβYYID 180
RDSGTCHSCP PNTILKAHQP YGVQACVPCG PGTKNNKIHS LCYNDCTFSR NTPTRTFNYN 240
FSALANTVTL AGGPSFTSKG LKYFHHFTLS LCGNQGRKMS VCTDNVTDLR IPEGESGFSK 300
SITAYVCQAV IIPPEVTGYK AGVSSQPVSL ADRLIGVTTD MTLDGITSPA ELFHLESLGI 360
PDVIFFYRSN DVTQSCSSGR STTIRVRCSP QKTVPGSLLL PGTCSDGTCD GCNFHFLWES 420
AAACPLCSVA DYHAIVSSCV AGIQKTTYVW REPKLCSGGI SLPEQRVTIC KTIDFWLKVG 480
ISAGTCTAIL LTVLTCYFWK KNQKLEYKYS KLVMNATLKD CDLPAADSCA IMEGEDVEDD 540
LIFTSKKSLF GKIKSFTSKQ PAPVTISLSE DS 572
Seq ID NO: C403 Protein Sequence Protein Accession ff: NP 055139.1 1 11 21 31 41 51 i i i i I I
MALQGISWE LSGLAPGRXC AMVLADFGAR RVDRPGSR YDVSRLGRGK RSLVLDLKQP 60
REPRAAASVQ AVGCAAGALP PRCHGETPAG PRDSAAGKSK AYLCQAEWIW PVQESFCRLA 120
GHDINYLALS GVLSKIGRSG ENPYAPLNLV ADFAGGGLMC ALGIIMALFD RTRTDKβQVI 180
DANMVEGTAY LSSFLWKTQK SSLWEAPRGQ NMLDGGAPFY TTYRTADβEF MAVβAIEPQF 240
YELLIKGLGL KSDELPNQMS TDDWPEMKKK FADVFAKKTK AEWCQIFDGT DACVTPVLTF 300
EEWHHDHNK ERGSFITSEE QDVSPRLAPL LLNTPAIPSS KGDPFIGEHT EEILEEFGFS 360
REEIYQLNSD KIIESNKVKA SL 382
Seq ID NO: C404 Protein Sequence Protein Accession ft: XP_091332.1
1 11 21 31 41 51
M IQRWTLWAAA FILTLHSAQAF PIQTDISISPA LIPELPLPSLC PILFWMEFKGH CIYRFFPLNKT 60
WAEADLYCSE FSVGRKSAKL ASIHSWEENV FVYDLVNSCV PGIPADVWTG LHDHRQEGQF 120
EWTDGSSYDY SYWDGSQPDD GVHADPEEED CVQIWYRPTS EQLQAPEPQL PLSISEATDV 180
YLPEDFPAEP KLMDQSWVSR KSLKPSKSHL MEPPTPVAKH QKAKTRHRSL RGVWWPSGKA 240
GSWKERMNAD YGRRKRSAPR QEGRLRCRER RLRAASGQGR PEGQRKQRQQ ERQERGWEEL 300
GGVSPMRGAQ AWQHGLGAGS QRGAAPECGE NHQAPELGST WRGQRLQPQT AALCHFALRK 360
LPGNAHGLAA AFVQPALQVQ EEKNNRTRFS GAYFTMSDPT CDQDSKEQSL RRHGREAEKD 420
GPYRLVKKKR GPVACPSSFE LQSGGEVCLD FPVELRAβTW IAREPP 466
Seq ID NO: C405 Protein Sequence Protein Accession #: XP 054869.2
1 11 21 31 41 51
I I I I I I
MHTCCPPVTL EQDLHRKMHS WMLQTLAFAV TSLVLSCAET IDYYGEICDN ACPCEEKDGI 60
LTVSCENRGI ISLSEISPPR FPIYHLLLSG NLLNRLYPNE FVNYTGASIL HLGSNVIQDI 120
ETGAFHGLRβ LRRLHLNNNK LELLRDDTFL GLENLEYLQV DYNYISVIEP NAFGKLHLLQ 180
VLILNDNLLS SLPNNLFRFV PLTHLDLRGN RLKLLPYVGL LQHMDKWEL QLEENPWNCS 240
CELISLKDWL DSISYSALVG DWCETPFRL HGRDLDEVSK QELCPRRLIS DYEMRPQTPL 300
STTβYLHTTP ASVNSVATSS SAVYKPPLKP PKβTRQPNKP RVRPTSRQPS KDLGYSNYGP 360
SIAYQTKSPV PLECPTACSC NLQISDLGLN VNCQERKIES IAELQPKPYN PKKMYLTENY 420
IAWRRTDFL EATGLDLLHL GNNRISMIQD RAFGDLTNLR RLYLNGNRIE RLSPELFYGL 480
QSLQYLFLQY NLIREIQSGT FDPVPNLQLL FLNNNLLQAM PSGVFSGLTL LRLNLRSNHF 540
TSLPVSGVLD QLKSLIQIDL HDNPWDCTCD IVGMKLWVEQ LKVGVLVDEV ICKAPKKFAE 600
TDMRSIKSEL LCPDYSDVW STPTPSSIQV PARTSAVTPA VRLNSTGAPA SLGAGββASS 660
VPLSVLILSL LLVFIMSVFV AAβLFVLVMK RRKKNQSDHT STNNSDVSSF NMQYSVYGGG 720
GGTGGHPHAH VHHRGPALPK VKTPAGHVYE YIPHPLGHMC KNPIYRSREG NSVEDYKDLH 780
ELKVTYSSNH HLQQQQQPPP PPQQPQQQPP PQLQLQPGEE ERRESHHLRS PAYSVSTIEP 840
REDLLSPVQD ADRFYRGILE PDKHCSTTPA GNSLPEYPKF PCSPAAYTFS PNYDLRRPHQ 900
YLHPGAGDSR LREPVLYSPP SAVFVEPNRN EYLELKAKLN VEPDYLEVLE KQTTFSQF 958
Seq ID NO: C406 Protein Sequence Protein Accession ft: NP 000784.2
1 11 21 31 41 51 i i i i i i
MGILSVDLLI TLQILPVFFS NCLFLALYDS VILLKHWLL LSRSKSTRGE WRRMLTSEβL 60
RCVWKSFLLD AYKQVKLGED APNSSWHVS STEGGDNSGN GTQEKIAEGA TCHLLDFASP 120
ERPLWNFGS ATUPPFTSQL PAFRKLVEEF SSVADFLLVY IDEAHPSD6W AIP6DSSLSF 180
EVKKHQNQED RCAAAQQLLE RFSLPPQCRV VADRMDNNAN IAYGVAFERV CIVQRQKIAY 240
LGβKβPFSYN LQEVRHWLEK NFSKRUKKTR LAG 273
Seq ID NO : C407 Protein Sequence Protein Accession ft : NP_006540 .2
1 11 21 31 41 51
M ISSCVSSQPS SINRAAPQDEL GIGRGSSSSES QIKPCEALRβL SISLSIHLGME SIFIWTECEP 60
GCAVDLGLAR DRPLEADGQE VPLDSSβSQA RPHLSβRKLS LQERSQGGLA AGGSLDMNGR 120
CICPSLPYSP VSSPQSSPRL PRRPTVESHH VSITGMQDCV QLNQYTLKDE IGKGSYGWK 180
LAYNENDNTY YAMKVLSKKK LIRQAGFPRR PPPRGTRPAP GGCIQPRGPI EQVYQEIAIL '240
KKLDHPNWK LVEVLDDPNE DHLYMVFELV NQGPVMEVPT LKPLSEDQAR FYFQDLIKGI 300
EYLHYQKIIH RDIKPSNLLV GEDGHIKIAD FGVSNEFKGS DALLSNTVGT PAFMAPESLS 360
ETRKIFΞGKA LDVWAMGVTL YCFVFGQCPF MDERIMCLHS KIKSQALEFP DQPDIAEDLK 420
DLITRMLDKN PESRIWPEI KLHPWVTRHG AEPLPSEDEN CTLVEVTEEE VENSVKHIPS 480
LATVILVKTM IRKRSFGNPF EGSRREERSL SAPGNLLTKK PTRECESLSE LKEARQRRQP 540
PGHRPAPRGG GGSALVRGSP CVESCWAPAP GSPARMHPLR PEEAMEPE 588
Seq ID NO: C408 Protein Sequence Protein Accession ff: NP 061116.2
1 11 21 31 41 51
I I I I 1 I
MGLSLPKEKG LILCLWSKFC RWFQRRESWA QSRDEQNLLQ QKRIWESPLL LAAKDNDVQA 60
LNKLLKYEDC KVHQRGAMGE TALHIAALYD NLEAAMVLME AAPELVFEPM TSELYEGQTA 120
LHIAWNQNM NLVRALLARR ASVSARATGT AFRRSPCNLI YFGEHPLSFA ACVNSEEIVR 180
LLIEHGADIR AQDSLGNTVL HILILQPNKT FACQMYNLLL SYDRHGDHLQ PLDLVPNHQG 240
LTPFKLAGVE βNTVMFQHLM QKRKHTQWTY GPLTSTLYDL TEIDSSGDEQ SLLELIITTK 300
KREARQILDQ TPVKELVSLK WKRYGRPYFC MLGAIYLLYI ICFTMCCIYR PLKPRTNNRT 360
SPRDNTLLQQ KLLQEAYMTP KDDIRLVGEL VTVIGAIIIL LVEVPDIFRM GVTRFFGQTI 420 LGGPFHVLII TYAFMVLVTM VMRLISASGE WPMSFALVL GWCNVMYFAR GFQMLGPFTI 480
MIQKMIFGDL MRFCWLMAW ILGFASAFYI IFQTEDPEEL GHFYDYPMAL FSTFELFLTI 540
IDGPANYNVD LPFMYSITYA AFAIIATLLM LNLLIAMMGD THWRVAHERD ELWRAQIVAT 600
TVMLERKLPR CLWPRSGICG REYGLGDRWF LRVEDRQDLN RQRIQRYAQA FHTRGSEDLD 660
KDSVEKLELG CPFSPHLSLP MPSVSRSTSR SSANWERLRQ GTLRRDLRGI INRGLEDGES 720
WEYQI 725
Seq ID NO: C409 Protein Sequence Protein Accession ft: NP_068710.1 I 11 21 31 41 51
I I I I I I
MQKVTLGLLV FLAGFPVLDA NDLEDKNSPF YYDWHSLQVG GLICAGVLCA MGIIIVMSEW 60 RSSGEQAGRG WGSPPLTTQL SPTGAKCKCK FGQKSGHHPβ ETPPLITPGS AQS 113
Seq ID NO: C410 Protein Sequence Protein Accession ft: NP 005962.1 - 1 11 21 31 41 51 0 i i i i i i
MQKVTLGLLV FLAβFPVLDA NDLEDKNSPF YYDWHSLQVG GLICAGVLCA MGIIIVMSAK 60 CKCKFGQKSG HHPGETPPLI TPGSAQS 87
Seq ID NO: C411 Protein Sequence 5 Protein Accession ff: NP 004952.1
1 11 21 31 41 51
I I I I I I
MLSKVLPVLL GILLILQSRV EGPQTESKNE ASSRDWYGP QPQPLENQLL SEETKSTETE 60 0 TGSRVGKLPE ASRILNTILS NYDHKLRPGI GEKPTWTVE IAVNSLGPLS ILDMEYTIDI 120
IFSQTWYDER LCYNDTFESL VLNGNWSQL WIPDTFFRNS KRTHEHEITM PNQMVRIYKD 180
GKVLYTIRMT IDAGCSLHML RFPMDSHSCP LSFSSFSYPE NEMIYKWENF KLEINEKNSW 240
KLFQFDFTGV SNKTEIITTP VGDFMVMTIF FNVSRRFGYV AFQNYVPSSV TTMLSWVSFW 300
IKTESAPART SLβlTSVLTM TTLGTFSRKN FPRVSYITAL DFYIAICFVF CFCALLEFAV 360 5 LNFLIYNQTK AHASPKLRHP RINSRAHART RARSRACARQ HQEAFVCQIV TTEGSDGEER 420
PSCSAQQPPS PGSPEGPRSL CSKLACCEWC KRFKKYFCMV PDCEGSTWQQ GRLCIHVYRL 480
DNYSRWFPV TFFFFNVLYW LVCLNL 506
Seq ID NO: C412 Protein Sequence 0 Protein Accession ff: NP_068819.1
1 11 21 31 41 51
I I I I I I
MEYTIDIIFS QTWYDERLCY NDTFESLVLN GNWSQLWIP DTFFRNSKRT HEHEITMPNQ 60 5 MVRIYKDGKV LYTIRMTIDA GCSLHMLRFP MDSHSCPLSF SSFSYPENEM IYKWENFKLE 120
INEKNSWKLF QLDFTGVSNK TEIITTPVGD FMVMTIFFNV SRRFGYVAFQ NYVPSSVTTM 180
LSWVSFWIKT ESAPARTSLG ITSVLTMTTL GTFSRKNFPR VSYITALDFY IAICFVFCFC 240
ALLEFAVLNF LIYNQTKAHA SPKLRHPRIN SRAHARTRAR SRACARQHQE AFVCQIVTTE 300
GSDGEERPSC SAQQPPSPGS PEGPRSLCSK LACCEWCKRF KKYFCMVPDC EGSTWQQARL 360 0 CIHVYRLDNY SRWFPVTFF FFNVLYWLVC LNL 393
Seq ID NO: C413 Protein Sequence Protein Accession #: NP 068822.1 5 1 11 21 31 41 51
I I I I I I
MEYTIDIIFS QTWNSKRTHE HEITMPNQMV RIYKDGKVLY TIRMTIDAGC SLHMLRFPMD 60
SHSCPLSFSS FSYPENEMIY KWENFKLEIN EKNSWKLFQF DFTGVSNKTE IITTPVGDFM 120
_- VMTIFFNVSR RFGYVAFQNY VPSSVTTMLS WVSFWIKTES APARTSLGIT SVLTMTTLGT 180
50 FSRKNFPRVS YITALDFYIA ICFVFCFCAL LEFAVLNFLI YNQTKAHASP KLRHPRINΞR 240
AHARTRARSR ACARQHQEAF VCQIVTTEGS DGEERPSCSA QQPPSPGSPE GPRSLCSKLA 300
CCEWCKRFKK YFCMVPDCEβ STWQQGRLCI HVYRLDNYSR WFPVTFFFF NVLYWLVCLN 360
L 361
55 Seq ID NO: C414 Protein Sequence Protein Accession ft: NP 068830.1
1 11 21 31 41 51
O ΛΛU M IEYTIDIIFS Q •TWYDERLCY N IDTFESLVLN G 'NWSQLWIP D ITFFRNSKRT H'EHEITMPNQ 60
MVRIYKDGKV LYTIRMTIDA GCSLHMLRFP MDSHSCPLSF SSFSYPENEM IYKWENFKLE 120
INEKNSWKLF QFDFTGVSNK TEIITTPVGD FMVMTIFFNV SRRFGYVAFQ NYVPSSVTTM 180
LSWVSFWIKT ESAPARTSLG ITSVLTMTTL GTFSRKNFPR VSYITALDFY IAICFVFCFC 240
ALLEFAVLNF LIYNQTKAHA SPKLRHPRIN SRAHARTRAR SRACARQHQE AFVCQIVTTE 300
65 GSDGEERPSC SAQQPPSPGS PEGPRSLCSK LACCEWCKRF KKYFCMVPDC EGSTWQQGRL 360
CIHVYRLDNY SRWFPVTFF FFNVLYWLVC LNL 393
Seq ID NO: C415 Protein Sequence Protein Accession #: NP_068591.1
70
1 11 21 31 41 51
I I I I I I
MPAVSGPGPL FCLLLLLLDP HSPETGCPPL RRFEYKLSFK GPRLALPGAG IPFWSHHGDA 60
ILGLEEVRLT PSMRNRSGAV WSRASVPFSA WEVEVQMRVT GLGRRGAHGM AVWYTRGRGH 120
75 VGSVLGGLAS WDGIGIFFDS PAEDTQDSPA IRVLASDGHI PSEQPGDGAS QβLGSCHWDF 180
RNRPHPFRAR ITYWGQRLRM SLNSGLTPSD PGEFCVDVGP LLLVPGGFFG VSAATGTLAD 240
DHDVLSFLTF SLSEPSPEVP PQPFLEMQQL RLARQLEGLW ARLGLGTRED VTPKSDSEAQ 300
GEGERLFDLE ETLGRHRRIL QALRGLSKQL AQAERQWKKQ LGPPGQARPD GβWALDASCQ 360
IPSTPGRGβH LSMSLNKDSA KVGALLHGQW TLLQALQEMR DAAVRMAAEA QVSYLPVGIE 420
80 HHFLELDHIL GLLQEELRGP AKAAAKAPRP PGQPPRASSC LQPGIFLFYL LIQTVGFFGY 480
VHFRQELNKS LQECLSTGSL PLGPAPHTPR ALGILRRQPL PASMPA 526
Seq ID NO: C416 Protein Sequence Protein Accession #: XP 117036.1 1 11 21 31 41 51
I I I I I I
MERRTRGALG SRRPPPPLPA LRHLCTGLQA AGMAWPGTLW RHTCQGRAXA AEGPWGLFRP 60 HRCPREAGQA PVGPSPETQG VAHVCSRARV SVDEREPGGG AYAMHVTPRW KGCHRHSGRT 120 VRGSVSWKRP EQAAPETβRG PAVARGSGDβ NECGWG 156
Seq ID NO: C417 Protein Sequence Protein Accession ft: XP_167803.2
10
1 11 21 31 41 51
I I I I I I
MPGKGQRKTA TNKPGβLPGA PGVGIββHCL YVLECKCFIK NKTKTHHHKK KNFAAKRNEE 60 KLKKKKKQEK KNHTKFFHHT YPLSQQDFLF AKSYFCGNGP CFLWQGLF 108
15
Seq ID NO: C418 Protein Sequence Protein Accession ff: NP 079056.1
_- 1 11 21 31 41 51
20 i i i ] i i
MFRLVERYEM PRHEVYVLLI RNIFLKISII GILCYYWLNT VALSGEECWE TLIGQDIYRL 60
LLMDFVFSLV NSFLGEFLRR IIGMQLITSL GLQEFDIARN VLELIYAQTL VWIGIFFCPL 120
LPFIQMIMLF IMFYSKNISL MMNFQPPSKA WRASQMMTFF IFLLFFPSFT GVLCTLAITI 180
WRLKPSADCG PFRGLPLFIH SIYSWIDTLS TRPGYLWWW IYRNLIGSVH FFFILTLIVL 240
25 IITYLYWQIT EGRKIMIRLL HEQIINEGKD KMFLIEKLIK LQDMEKKANP SSLVLERREV 300
EQQGFLHLGE HDGSLDLRSR RSVQEGNPRA 330
Seq ID NO: C419 Protein Sequence Protein Accession ff: Eos sequence
30
1 11 21 31 41 51
I I I I I I
MLSDDHVNEI IIQVENVSSG VQSHPSSNQI FQEKVLLDSS INMVLSISDI DVIDSQTVSK 60
RNDQKGNQVL RFSTSLNESM SQTLHSLECM GIDTPGSSHE TVQGQKLIAS LIPMTSRDRI 120
35 KAIRNQPRTM EEKRNLRKIV DKEKSKQTHR ILQLNCCIQC LNSISRAYRR SKNSLSEILN 180
SISLWQKTLK IIGGKFGTSV LSYFNFLRWL LKFNIFSFIL NFSFIIIPQF TVAKKNTLQF 240
TGLEFFTGVG YFRDTVMYYG FYTNSTIQHG NSGASYNMQL AYIFTIGACL TTCFFSLLFS 300
MAKYFRNNFI NPHIYSGGIT KLIFCWDFTV THEKAVKLKQ KNLSTEIREN LSELRQENSK 360
LTFNQLLTRF SAYMVAWWS TGVAIACCAA VYYLAEYNLE FLKTHSNPGA VLLLPFWSC 420
40 INLAVPCIYS MFRLVERYEM PRHEVYVLLI RNIFLKISII GILCYYWLNT VALSGEECWE 480
TLIGQDIYRL LLMDFVFSLV NSFLGEFLRR IIGMQLITSL GLQEFDIARN VLELIYAQTL 540
VWIGIFFCPL LPFIQMIMLF IMFYSKNISL MMNFQPPSKA WRASQMMTFF IFLLFFPSFT 600
GVLCTLAITI WRLKPSADCG PFRGLPLFIH SIYSWIDTLS TRPβYLWWW IYRNLIGSVH 660
FFFILTLIVL IITYLYWQIT EGRKIMIRLL HEQIINEGKD KMFLIEKLIK LQDMEKKANP 720
45 SSLVLERREV EQQGFLHLGE HDGSLDLRSR RSVQEGNPRA 760
Seq ID NO: C420 Protein Sequence Protein Accession ft: NP_002241.1
50 1 11 21 31 41 51
I I 1 I I I
MGGDLVLGLG ALRRRKRLLE QEKSLAGWAL VLAGTGIGLM VLHAEMLWFG GCSWALYLFL 60
VKCTISISTF LLLCLIVAFH AKEVQLFMTD NGLRDWRVAL TCRQAAQIVL ELWC6LHPA 120
PVRGPPCVQD LGAPLTSPQP WPGFLGQGEA LLSLAMLLRL YLVPRAVLLR SGVLLNASYR 180
55 SIGALNQVRF RHWFVAKLYM NTHPGRLLLG LTLGLWLTTA WVLSVAERQA VNATGHLSDT 240
LWLIPITFLT IGYGDWPGT MWGKIVCLCT GVMGVCCTAL LVAWARKLE FNKAEKHVHN 300
FMMDIQYTKE MKESAARVLQ EAWMFYKHTR RKESHAARRH QRKLLAAINA FRQVRLKHRK 360
LREQVNSMVD ISKMHMILYD LQQNLSSSHR ALEKQIDTLA GKLDALTELL STALGPRQLP 420
EPSQQSK 427
60
Seq ID NO: C421 Protein Sequence Protein Accession ft: NP 079533.1
._ 1 11 21 31 41 51
65 i i i i i i
MGGKQRDEDD EAYGKPVKYD PSFRGPIKNR SCTDVICCVL FLLFILGYIV VGIVAWLYGD 60
PRQVLYPRNS TGAYCGMGEN KDKPYLLYFN IFSCILSSNI ISVAENGLQC PTPQVCVSSC 120
PEDPWTVGKN EFSQTVGEVF YTKNRNFCLP GVPWNMTVIT SLQQELCPSF LLPSAPALGR 180
CFPWTNITPP ALPGITNDTT IQQGISGLID SLNARDISVK IFEDFAQSWY WILVALGVAL 240
70 VLSLLFILLL RLVAGPLVLV LILGVLGVLA YGIYYCWEEY RVLRDKGASI SQLGFTTNLS 300
AYQSVQETWL AALIVLAVLE AILLLVLIFL RQRIRIAIAL LKEASKAVGQ MMSTMFYPLV 360
TFVLLLICIA YWAMTALYPL PTQPATLGYV LWASNISSPG CEKVPINTSC NPTAHLVNSS 420
CPGLMCVFQG YSSKGLIQRS VFNLQIYGVL GLFWTLNWVL ALGQCVLAGA FASFYWAFHK 480
PQDIPTFPLI SAFIRTLRYH TGSLAFGALI LTLVQIARVI LEYIDHKLRG VQNPVARCIM 540
75 CCFKCCLWCL EKFIKFLNRN AYIMIAIYGK NFCVSAKNAF MLLMRNIVRV LDKVTDLL 600
LFFGKLLWG GVGVLSFFFF SGRIPGLGKD FKSPHLNYYW LPIMTSILGA YVIASGFFSV 660
FGMCVDTLFL CFLEDLERNN GSLDRPYYMS KSLLKILGKK NEAPPDNKKR KK 712
Seq ID NO: C422 Protein Sequence
80 Protein Accession ff: NP_057264.1
1 11 21 31 41 51
I I I I I I
MGSNSGQAβR HIYKSLADDG PFDSVEPPKR PTSRLIMHSM AMFGREFCYA VEAAYVTPVL 60 LSVβLPSSLY SIVWFLSPIL βFLLQPWGS ASDHCRSRWG RRRPYILTLG VMMLVGMALY 120
LNβATWAAL IANPRRKLVW AISVTMIGW LFDFAADFID GPIKAYLFDV CSHQDKEKGL 180
HYHALFTGFG GALGYLLGAI DWAHLELGRL LGTEFQVMFF FSALVLTLCF TVHLCSISEA 240
PLTEVAKGIP PQQTPQDPPL SSDβMYEYβS IEKVKNGYVN PELAMQGAKN KNHAEQTRRA 300
MTLKSLLRAL VNMPPHYRYL CISHLIGWTA FLSNMLFFTD FMGQIVYRGD PYSAHNSTEF 360
LIYERGVEVβ CWGFCINSVF SSLYSYFQKV LVSYIGLKGL YFTGYLLFGL GTGFIGLFPN 420
VYSTLVLCSL FGVMSSTLYT VPFNLITEYH REEEKERQQA PGGDPDNSVR GKGMDCATLT 480
CMVQLAQILV GGGLGFLVNT AGTWVWIT ASAVALIGCC FVALFVRYVD 530
Seq ID NO C423 Protein Sequence Protein Accession tf NP_003264.1
1 11 21 31 41 51
I I I I I I
MEGFGGVGGR βTRβFAAKβV WRGRAEEGPV LGAAERGFMV STGSRRRVFE GPGGGGLRWT 60
PGKGTGRQRG AWGPRAEDGV RRRTLGMPRG SRRDVRAPCG PAGSWGARGG RRRDGPSRRR 120
RGSATAAARH HVPPAPGGPF GPRAPAGSTR VPARAGGAVE PTGAAAVARL ARPAGβALPT 180
AβAQGAGPAR GRSβEGSEWA RRGKGRPGPY QSPLGPAVAE GQELKDKSRL RYPINGFQAL 240
VLTALLVGLG MSAGLPLGAL PEMLLPLAFV ATLTAFIFSL FLYMKAQVAP VSALAPGGNS 300
GNPIYDFFLG RELNPRICFF DFKYFCELRP GLIGWVLINL ALLMKEAELR GSPSLAMWLV 360
NGFQLLYVGD ALWHEEAVLT TMDITHDGFG FMLAFGDMAW VPFTYSLQAQ FLLHHPQPLG 420
LPMASVICLI NATGYYIFRG ANSQKNTFRK NPSDPRVAβL ETISTATGRK LLVSGWWGMV 480
RHPNYLGDLI MALAWSLPCG VSHLLPYFYL LYFTALLVHR EARDERSACR STAWPGRSTA 540
GVCLTASCPT STEAAPPPQV GHVPTHPPAH PGPGASTHLG LKGLHPTQP 589
Seq ID NO- C424 Protem Sequence Protem Accession ff: NP 056535.1 1 11 21 31 41 51 i i i i i i
MGRLLRAARL PPLLSPLLLL LVGGAFLGAC VAGSDEPGPE GLTSTSLLDL LLPTGLEPLD 60
SEEPSETMGL GAGLGAPGSG FPSEENEESR ILQPPQYFWE EEEELNDSSL DLGPTADYVF 120
PDLTEKAGSI EDTSQAQELP NLPSPLPKMN LVEPPWHMPP REEEEEEEEE EEREKEEVEK 180
QEEEEEEELL PVNGSQEEAK PQVRDFSLTS SSQTPGATKS RHEDSGDQAS SGVEVESSMG 240
PSLLLPSVTP TTVTPGDQDS TSQEAEATVL PAAGLGVEFE APQEASEEAT AGAAGLSGQH 300
EEVPALPSFP QTTAPSGAEH PDEDPLGSRT SASSPLAPGD MELTPSSATL GQEDLNQQLL 360
EGQAAEAQSR IPWDSTQVIC KDWSNLAβKN YIILNMTENI DCEVFRQHRG PQLLALVEEV 420
LPRHGSGHHG AWHISLSKPS EKEQHLLMTL VGEQGWPTQ DVLSMLGDIR RSLEEIGIQN 480
YSTTSSCQAR ASQVRSDYGT LFWLWIβA ICIIIIAL6L LYNCWQRRLP KLKHVSHβEE 540
LRFVENβCHD NPTLDVASDS QSEMQEKHPS LNGGGALNGP GSWGALMGGK RDPEDSDVFE 600
EDTHL 605
Seq ID NO- C425 Protein Sequence Protem Accession ft- NP_001188.1
1 11 21 31 41 51
I I I I I I
MSEVRPLSRD ILMETLLYEQ LLEPPTMEVL GMTDSEEDLD PMEDFDSLEC MEGSDALALR 60
LACIGDEMDV SLRAPRLAQL SEVAMHSLGL AFIYDQTEDI RDVLRSFMDG FTTLKENIMR 120
FWRSPNPGSW VSCEQVLLAL LLLLALLLPL LSGGLHLLLK 160
Seq ID NO: C426 Protein Sequence Protem Accession tf: AAF76225.1
1 11 21 31 41 51
I I I I I 1
MATPLPPPSP RHLRLLRLLL SGLVLGAALR GAAAGHPDVA ACPGSLDCAL KRRARCPPGA 60
HACGPCLQPF QEDQQGLCVP RMRRPPGGGR PQPRLEDEID FLAQELARKE SGQSTPPLPK 120
DRQRLPEPAT LGFSARGQGL ELGLPSTPGT PTPTPHTSLβ SPVSSDPVHM SPLEPRGGQG 180
DGLALVLILA FCVAGAAALS VASLCWCRLQ REIRLTQKAD YATAKAPGSP AAPRISPGDQ 240
RLAQSAEMYH YQHQRQQMLC LERHKEPPKE LDTASSDEEN EDGDFTVYEC PβLAPTGEME 300
VRNPLFDHAA LSAPLPAPSS PPALP 325
Seq ID NO. C427 Protein Sequence Protein Accession ft: NP_004436.1
1 11 21 31 41 51
I I I I I I
MVCSLWVLLL VSSVLALEEV LLDTTGETSE IGWLTYPPGG WDEVSVLDDQ RRLTRTFEAC 60
HVAGAPPGTG QDNWLQTHFV ERRGAQRAHI RLHFSVRACS SLGVSGGTCR ETFTLYYRQA 120
EEPDSPDSVS SWHLKRWTKV DTIAADESFP SSSSSSSSSS SAAWAVGPHG AGQRAGLQLN 180
VKERSFGPLT QRGFYVAFQD TGACLALVAV RLFSYTCPAV LRSFASFPET QASGAGβASL 240
VAAVGTCVAH AEPEEDGVGG QAGGSPPRLH CNGEGKWMVA VGGCRCQPGY QPARGDKACQ 300
ACPRGLYKSS AGNAPCSPCP ARSHAPNPAA PVCPCLEGFY RASSDPPEAP CTGPPSAPQE 360
LWFEVQGSAL MLHWRLPREL GGRGDLLFNV VCKECEGRQE PASGGGGTCH RCRDEVHFDP 420
RQRGLTESRV LVGGLRAHVP YILEVQAVNG VSELSPDPPQ AAAINVSTSH EVPSAVP H 480
QVSRASNSIT VSWPQPDQTN GNILDYQLRY YDQAEDESHS FTLTSETNTA TVTQLSPβHI 540
YGFQVRARTA AGHGPYG6KV YFQTLPQGEL SSQLPERLSL VIGSILGALA FLLLAAITVL 600
AWFQRKRRG TGYTEQLQQY SSPGLGVKYY IDPSTYEDPC QAIRELAREV DPAYIKIEEV 660
IGTGSFGEVR QGRLQPRGRR EQTVAIQALW AGGAESLQMT FLGRAAVLβQ FQHPNILRLE 720
GWTKSRPLM VLTEFMELGP LDSFLRQREG QFSSLQLVAM QRGVAAAMQY LSSFAFVHRS 780
LSAHSVLVNS HLVCKVARLG HSPQGPSCLL RWAAPEVIAH GKHTTSSDVW SFGILMWEVM 840
SYGERPYWDM SEQEVLNAIE QEFRLPPPPG CPPGLHLLML DTWQKDRARR PHFDQLVAAF 900
DKMIRKPDTL QAGGDPGERP SQALLTPVAL DFPCLDSPQA WLSAIGLECY QDNFSKFGLC 960 TFSDVAQLSL EDLPALGITL AGHQKKLLHH IQLLQQHLRQ QGSVEV 1006
Seq ID NO: C428 Protein Sequence Protein Accession tf: XP_043340.2
1 11 21 31 41 51
I I I I I I
MPFDFRRFDI YRKVPKDLTQ PTYTGAIISI CCCLFILFLF LSELTGFITT E NELYVDD 60
PDKDSGGKID VSLNISLPNL HCELVGLDIQ DEMGRHEVGH IDNSMKIPLN NGAGCRFEGQ 120
FSINKVPGNF HVSTHSATAQ PQNPDMTHVI HKLSFGDTLQ VQNIHGAFNA LGβADRLTSN 180
PLASHDYILK IVPTVYEDKS GKQRYSYQYT VANKEYVAYS HTGRIIPAIW FRYDLSPITV 240
KYTERRQPLY RFITTICAII GGTFTVAGIL DSCIFTASEA WKKIQLGKMH 290
Seq ID NO: C429 Protein Sequence Protein Accession #: NP 002142.1
1 11 21 31 41 51
I I 'I I I I
MAQKEGGRTV PCCSRPKVAA LTAGTLLLLT AIGAASWAIV AVLLRSDQEP LYPVQVSSAD 60 ARLMVFDKTE GTWRLLCSSR SNARVAGLSC EEMGFLRALT HSELDVRTAG ANGTSGFFCV 120
DEGRLPHTQR LLEVISVCDC PRGRFLAAIC QDCGRRKLPV DRIVGGRDTS LGRWPWQVSL 180
RYDGAHLCGG SLLSGDWVLT AAHCFPERNR VLSRWRVFAG AVAQASPHGL QLGVQAWYH 240
GGYLPFRDPN SEENSNDIAL VHLSSPLPLT EYIQPVCLPA AGQALVDGKI CTVTGWGNTQ 300
YYGQQAGVLQ EARVPIISND VCNGADFYGN QIKPKMFCAG YPEGGIDACQ GDSGGPFVCE 360 DSISRTPRWR LCGIVSWβTG CALAQKPGVY TKVSDFREWI FQAIKTHSEA SGMVTQL 417
Seq ID NO: C430 Protein Sequence Protein Accession ft: BAA92562.1
1 11 21 31 41 51
I I I I I I
METTVLSGIN FEYKGMTGWE VAGDHIYTAA GASDNDFMIL TLWPGFRPP QSVMADTENK 60
EVARITFVFE TLCSVNCELY FMVGVNSRTN TPVETWKGSK GKQSYTYIIE ENTTTSFTWA 120
FQRTTFHEAS RKYTNDVAKI YSINVTNVMN GVASYCRPCA LEASDVβSSC TSCPAGYYID 180 RDSGTCHSCP PNTILKAHQP YGVQACVPCG PGTKNNKIHS LCYNDCTFSR NTPTRTFNYN 240
FSALANTVTL AGGPSFTSKG LKYFHHFTLS LCGNQβRKMS VCTDNVTDLR IPEGESGFSK 300
SITAYVCQAV IIPPEVTGYK AGVSSQPVSL ADRLIGVTTD MTLDGITSPA ELFHLESLGI 360
PDVIFFYRSN DVTQSCSSGR STTIRVRCSP QKTVPβSLLL PGTCSDGTCD GCNFHFLWES 420 AAACPLCSVA DYHAIVSSCV AGIQKTTYVW REPKLCSGGI SLPEQRVTIC KTIDFWLKVG 480 ISAGTCTAIL LTVLTCYFWK KNQKLEYKYS KLVMNATLKD CDLPAADSCA IMEGEDVEDD 540
LIFTSKKSLF GKIKSFTSKQ PAPVTISLSE DS 572
Seq ID NO: C431 Protein Sequence Protein Accession ft: NP_004855.1
1 11 21 31 41 51
I I I I 1 I
MPGQELRTVN GSQMLLVLLV LSWLPHGGAL SLAEASRASF PGPSELHSED SRFRELRKRY 60
EDLLTRLRAN QSWEDSNTDL VPAPAVRILT PEVRLGSβGH LHLRISRAAL PEGLPEASRL 120
HRALFRLSPT ASRSWDVTRP LRRQLSLARP QAPALHLRLS PPPSQSDQLL AESSSARPQL 180
ELHLRPQAAR GRRRARARNβ DDCPLGPGRC CRLHTVRASL EDLGWADWVL SPREVQVTMC 240
IβACPSQFRA ANMHAQIKTS LHRLKPDTEP APCCVPASYN PMVLIQKTDT GVSLQTYDDL 300
LAKDCHCI 308
Seq ID NO: C433 Protein Sequence Protein Accession #: NP_443090.1
1 11 21 31 41 51
I I I I I I
MEDPSGAREP RARPRERDPG RRPHPDQGRT HDRPRDRPGD PRRKRSSDGN RRRDGDRDPK 60
RDQERDGNRD RNRDRERERE RERDPDRGPR RDTHRDAGPR AGEHGVWEKP RQSRTRDGAR 120
GLTWDAAAPP GPAPWEAPEP PQPQRKGDPG RRRPESEPPS ERYLPSTPRP GREEVEYYQS 180
EAEGLLECHK CKYLCTGRAC CQMLEVLLNL LILACSSVSY SSTGGYTGIT SLGβlYYYQF 240
GGAYSGFDGA DGEKAQQLDV QFYQLKLPMV TVAMACSβAL TALCCLFVAM GVLRVPWHCP 300
LLLVTEGLLD MLIAGGYIPA LYFYFHYLSA AYβSPVCKER QALYQSKβYS GFGCSFHGAD 360
IGAGIFAALG IWFALGAVL AIKGYRKVRK LKEKPAEMFE F 401
Seq ID NO: C435 Protein Sequence Protein Accession ft: Eos sequence
1 11 21 31 41 51
I I I I I I
MGAAGRQDFL FKAMLTISWL TLTCFPGATS TVAAGCPDQS PELQPWNPGH DQDHHVHIGQ 60
GKTLLLTSSA TVYSIHISEG GKLVIKDHDE PIVLRTRHIL IDNGGELHAG SALCPFQGNF 120 TIILYGRADE GIQPDPYYGL KYIGVGKGβA LELHGQKKLS WTFLNKTLHP GGMAEGGYFF 180
ERSWβHRGVI VHVIDPKSGT VIHSDRFDTY RSKKESERLV QYLNAVPDGR ILSVAVNDEG 240
SRNLDDMARK AMTKLGSKHF LHLGFRHPWS FLTVKGNPSS SVEDHIEYHG HRGSAAARVF 300
KLFQTEHGEY FNVSLSSEWV QDVEWTEWFD HDKVSQTKGG EKISDLWKAH PGKICNRPID 360
IQATTMDβVN LSTEWYKKG QDYRFACYDR GRACRSYRVR FLCGKPVRPK LTVTIDTNVN 420
STILNLEDNV QSWKPGDTLV IASTDYSMYQ AEEFQVLPCR SCAPNQVKVA GKPMYLHIGE 480
EIDGVDMRAE VGLLSRNIIV MGEMEDKCYP YRNHICNFFD FDTFGGHIKF ALGFKAAHLE 540
GTELKHMGQQ LVGQYPIHFH LAGDVDERβG YDPPTYIRDL SIHHTFSRCV TVHGSNGLLI 600
KDWGYNSLβ HCFFTEDGPE ERNTFDHCLG LLVKΞβTLLP SDRDSKMCKM ITEDSYPGYI 660
PKPRQDCNAV STFWMANPNN NLINCAAAGS EETGFWFIFH HVPTGPSVGM YSPGYSEHIP 720 LGKFYNNRAH SNYRAGMI ID NGVKTTEASA KDKRPFLSII SARYSPHQDA DPLKPREPAI 780
IRHFIAYKNQ DHGAWLRGGD VWLDSCHFRG EAQEGFLLTG MKAGβlLLGG DEAASGMAQG 840 FSPPCRCLLK LVTTGSPFAH VSLAHS 866
It is understood that the examples described above in no way serve to limit the true scope of this invention, but rather are presented for illustrative purposes. All publications, sequences of accession numbers, and patent applications cited in this specification are herein incorporated by reference as if each individual publication, accession number, or patent application were specifically and individually indicated to be incorporated by reference.

Claims

WHAT IS CLAIMED IS:
1. A method for determining the presence or absence of a pathological cell in a patient, said method comprising detecting a nucleic acid comprising a sequence at least 80% identical to a sequence as described in Tables 2A-80 in a biological sample from said patient, thereby determining the presence or absence of said pathological cell.
2. The method of Claim 1, wherein: a) said pathology is described in Table 1, including a cancer; and/or b) said biological sample comprises isolated nucleic acids.
3. The method of Claim 1 , wherein said biological sample is tissue from an organ which is affected by said pathology of Table 1 , including a cancer.
4. The method of Claim 2, wherein said nucleic acids are mRNA
5. The method of Claim 2: a) further comprising a step of amplifying nucleic acids before said step of detecting said nucleic acid; or b) where said detecting is of a protein encoded by said nucleic acid.
6. The method of Claim 1, wherein said nucleic acid comprises a sequence as described in Tables 2A-80.
7. The method of Claim 2, wherein: a) said detecting step is carried out by: i) using a labeled nucleic acid probe; ii) utilizing a biochip comprising a sequence at least 80% identical to a sequence as described in Tables 2A-80; or iii) detecting a polypeptide encoded by said nucleic acid; or b) said patient is: i) undergoing a therapeutic regimen to treat said pathology of Table 1 ; or ii) is suspected of having said pathology or cancer.
8. An isolated nucleic acid molecule comprising a sequence as described in Tables 2A-80.
9. The nucleic acid molecule of Claim 8, which is labeled.
10. An expression vector comprising the nucleic acid of Claim 8.
11. A host cell comprising the expression vector of Claim 10.
12. An isolated polypeptide which is encoded by a nucleic acid molecule comprising a sequence as described in Tables 2A-80.
13. An antibody that specifically binds a polypeptide of Claim 12.
14. The antibody of Claim 13 : a) conjugated to an effector component; b) conjugated to a detectable label, including a fluorescent label, a radioisotope, or a cytotoxic chemical; c) which is an antibody fragment; or d) which is a humanized antibody.
15. A method for specifically targeting a compound to a pathological cell in a patient, said method comprising administering to said patient an antibody of Claim 13, thereby providing said targetting.
16. A method for determining the presence or absence of a pathological cell in a patient, said method comprising contacting a biological sample with an antibody of Claim 13.
17. The method of Claim 16, wherein: a) said antibody is conjugated to: i) an effector component; or ii) a fluorescent label; or b) said biological sample is a blood, serum, urine, or stool sample.
18. A method for identifying a compound that modulates a pathology- associated polypeptide, said method comprising the steps of: a) contacting said compound with a pathology-associated polypeptide, said polypeptide encoded by a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as described in Tables 2A-80; and b) determining the functional effect of said compound upon said polypeptide.
19. A drug screening assay comprising the steps of: a) administering a test compound to a mammal having a pathology of Table 1 or a cell isolated therefrom; and b) comparing the level of gene expression of a polynucleotide that selectively hybridizes to a sequence at least 80% identical to a sequence as described in Tables 2A-80 in a treated cell or mammal with the level of gene expression of said polynucleotide in a control cell or mammal, wherein a test compound that modulates said level of expression of the polynucleotide is a candidate for the treatment of said pathology.
PCT/US2002/036810 2001-11-13 2002-11-13 Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer WO2003042661A2 (en)

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CA002467433A CA2467433A1 (en) 2001-11-13 2002-11-13 Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
EP02792272A EP1497454A2 (en) 2001-11-13 2002-11-13 Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
JP2003544445A JP2005525789A (en) 2001-11-13 2002-11-13 Cancer diagnosis method, cancer modulator screening composition and method
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US33439301P 2001-11-29 2001-11-29
US60/334,393 2001-11-29
US33539401P 2001-12-03 2001-12-03
US60/335,394 2001-12-03
US34037601P 2001-12-14 2001-12-14
US60/340,376 2001-12-14
US34721102P 2002-01-08 2002-01-08
US60/347,211 2002-01-08
US34734902P 2002-01-10 2002-01-10
US60/347,349 2002-01-10
US35525002P 2002-02-08 2002-02-08
US35525702P 2002-02-08 2002-02-08
US60/355,250 2002-02-08
US35671402P 2002-02-13 2002-02-13
US60/356,714 2002-02-13
US35907702P 2002-02-20 2002-02-20
US60/359,077 2002-02-20
US36880902P 2002-03-29 2002-03-29
US60/368,809 2002-03-29
US37011002P 2002-04-04 2002-04-04
US60/370,110 2002-04-04
US37224602P 2002-04-12 2002-04-12
US60/372,246 2002-04-12
US38661402P 2002-06-05 2002-06-05
US60/386,614 2002-06-05
US39683902P 2002-07-16 2002-07-16
US60/396,839 2002-07-16
US39784502P 2002-07-22 2002-07-22
US39777502P 2002-07-22 2002-07-22
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