WO2003032957A3 - Methods for hermetically sealing microchip reservoir devices - Google Patents

Methods for hermetically sealing microchip reservoir devices Download PDF

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Publication number
WO2003032957A3
WO2003032957A3 PCT/US2002/020490 US0220490W WO03032957A3 WO 2003032957 A3 WO2003032957 A3 WO 2003032957A3 US 0220490 W US0220490 W US 0220490W WO 03032957 A3 WO03032957 A3 WO 03032957A3
Authority
WO
WIPO (PCT)
Prior art keywords
substrate
hermetic
hermetic sealing
sealing
methods
Prior art date
Application number
PCT/US2002/020490
Other languages
French (fr)
Other versions
WO2003032957A2 (en
WO2003032957A9 (en
Inventor
Scott A Uhland
Benjamin F Polito
Stephen J Herman
John T Santini Jr
Original Assignee
Microchips Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microchips Inc filed Critical Microchips Inc
Priority to JP2003535761A priority Critical patent/JP2005505429A/en
Priority to EP02797022A priority patent/EP1399135B1/en
Priority to AT02797022T priority patent/ATE285756T1/en
Priority to AU2002361545A priority patent/AU2002361545B2/en
Priority to DE60202468T priority patent/DE60202468T2/en
Priority to CA002451953A priority patent/CA2451953A1/en
Publication of WO2003032957A2 publication Critical patent/WO2003032957A2/en
Publication of WO2003032957A3 publication Critical patent/WO2003032957A3/en
Publication of WO2003032957A9 publication Critical patent/WO2003032957A9/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips

Abstract

Methods are provided for hermetically sealing the reservoirs of microchip devices and for hermetically sealing the substrate assemblies in a hermetic packaging structure. In one embodiment, the method comprises (1) providing a primary substrate having a front side and a back side, the substrate comprising a plurality of reservoirs positioned between the front side and the back side, each reservoir being loaded with molecules or a secondary device for controlled release or exposure, the reservoirs having at least one opening in need of sealing, the primary substrate including one or more hermetic sealing materials; (2) providing a hermetic sealing substrate having a surface composed of one or more hermetic sealing materials; (3) positioning the hermetic sealing substrate over the reservoir openings and contacting said hermetic sealing materials of the primary substrate with said hermetic sealing materials of the hermetic sealing substrate; and (4) applying energy or a mechanical force to the contacted sealing materials effective to form a hermetic seal between the hermetic sealing substrate and the primary substrate to hermetically seal the reservoir openings.
PCT/US2002/020490 2001-06-28 2002-06-28 Methods for hermetically sealing microchip reservoir devices WO2003032957A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2003535761A JP2005505429A (en) 2001-06-28 2002-06-28 Method for hermetically sealing a microchip reservoir device
EP02797022A EP1399135B1 (en) 2001-06-28 2002-06-28 Methods for hermetically sealing microchip reservoir devices
AT02797022T ATE285756T1 (en) 2001-06-28 2002-06-28 METHOD FOR HERMETIC SEALING MICROCHIP RESERVOIR DEVICES
AU2002361545A AU2002361545B2 (en) 2001-06-28 2002-06-28 Methods for hermetically sealing microchip reservoir devices
DE60202468T DE60202468T2 (en) 2001-06-28 2002-06-28 METHOD FOR THE HERMETIC SEALING OF MICROCHIP RESERVOIR DEVICES
CA002451953A CA2451953A1 (en) 2001-06-28 2002-06-28 Methods for hermetically sealing microchip reservoir devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30168601P 2001-06-28 2001-06-28
US60/301,686 2001-06-28

Publications (3)

Publication Number Publication Date
WO2003032957A2 WO2003032957A2 (en) 2003-04-24
WO2003032957A3 true WO2003032957A3 (en) 2003-10-16
WO2003032957A9 WO2003032957A9 (en) 2004-05-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/020490 WO2003032957A2 (en) 2001-06-28 2002-06-28 Methods for hermetically sealing microchip reservoir devices

Country Status (8)

Country Link
US (2) US6827250B2 (en)
EP (1) EP1399135B1 (en)
JP (2) JP2005505429A (en)
AT (1) ATE285756T1 (en)
AU (1) AU2002361545B2 (en)
CA (1) CA2451953A1 (en)
DE (1) DE60202468T2 (en)
WO (1) WO2003032957A2 (en)

Families Citing this family (189)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6783543B2 (en) * 2000-06-05 2004-08-31 Scimed Life Systems, Inc. Intravascular stent with increasing coating retaining capacity
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US7341598B2 (en) 1999-01-13 2008-03-11 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
CA2358296A1 (en) * 1999-01-05 2000-07-13 Anthony P. Adamis Targeted transscleral controlled release drug delivery to the retina and choroid
CA2381951A1 (en) * 1999-08-18 2001-02-22 Microchips, Inc. Thermally-activated microchip chemical delivery devices
DE60027458T2 (en) * 1999-12-10 2007-07-05 Massachusetts Institute Of Technology, Cambridge MICROCHIP DRUG DISABLING SYSTEMS AND MANUFACTURING METHOD
WO2001064344A2 (en) 2000-03-02 2001-09-07 Microchips, Inc. Microfabricated devices for the storage and selective exposure of chemicals and devices
EP1772114B1 (en) * 2000-06-05 2011-09-28 Boston Scientific Limited Intravascular stent with increasing coating retaining capacity
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
ATE359762T1 (en) * 2001-01-09 2007-05-15 Microchips Inc FLEXIBLE MICROCHIP DEVICES FOR OPHTHALMOLOGICAL AND OTHER APPLICATIONS
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP1404232B1 (en) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Blood sampling apparatus and method
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
DE60238119D1 (en) 2001-06-12 2010-12-09 Pelikan Technologies Inc ELECTRIC ACTUATOR ELEMENT FOR A LANZETTE
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7316700B2 (en) 2001-06-12 2008-01-08 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
ATE285756T1 (en) * 2001-06-28 2005-01-15 Microchips Inc METHOD FOR HERMETIC SEALING MICROCHIP RESERVOIR DEVICES
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7828728B2 (en) 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
AU2003217531A1 (en) * 2002-05-02 2003-11-17 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US6953455B2 (en) * 2002-07-30 2005-10-11 Hospira, Inc. Medicine delivery system
AU2003303288B2 (en) * 2002-08-16 2006-12-07 Microchips, Inc. Controlled release device and method
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
WO2004026281A2 (en) * 2002-09-23 2004-04-01 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
WO2004033036A2 (en) 2002-10-04 2004-04-22 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
AU2003284018A1 (en) * 2002-10-04 2004-05-04 Microchips, Inc. Medical device for neural stimulation and controlled drug delivery
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
SG157957A1 (en) * 2003-01-29 2010-01-29 Interplex Qlp Inc Package for integrated circuit die
WO2004073551A2 (en) * 2003-02-18 2004-09-02 Massachusetts Eye And Ear Infirmary Transscleral drug delivery device and related methods
US7002727B2 (en) * 2003-03-31 2006-02-21 Reflectivity, Inc. Optical materials in packaging micromirror devices
CA2523432C (en) * 2003-04-25 2014-10-28 Microchips, Inc. Solid drug formulation and device for storage and controlled delivery thereof
US8262614B2 (en) 2003-05-30 2012-09-11 Pelikan Technologies, Inc. Method and apparatus for fluid injection
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7114312B2 (en) * 2003-07-17 2006-10-03 Microchips, Inc. Low temperature methods for hermetically sealing reservoir devices
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7074307B2 (en) 2003-07-25 2006-07-11 Dexcom, Inc. Electrode systems for electrochemical sensors
EP1648298A4 (en) 2003-07-25 2010-01-13 Dexcom Inc Oxygen enhancing membrane systems for implantable devices
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
WO2005016558A2 (en) * 2003-08-04 2005-02-24 Microchips, Inc. Methods for accelerated release of material from a reservoir device
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7612443B1 (en) * 2003-09-04 2009-11-03 University Of Notre Dame Du Lac Inter-chip communication
US20060287602A1 (en) * 2005-06-21 2006-12-21 Cardiomems, Inc. Implantable wireless sensor for in vivo pressure measurement
US8026729B2 (en) 2003-09-16 2011-09-27 Cardiomems, Inc. System and apparatus for in-vivo assessment of relative position of an implant
EP1677852A4 (en) 2003-09-16 2009-06-24 Cardiomems Inc Implantable wireless sensor
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc Method and apparatus for a variable user interface
US20050090607A1 (en) * 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
AU2004285603A1 (en) 2003-11-03 2005-05-12 Microchips, Inc. Medical device for sensing glucose
DE602004028649D1 (en) * 2003-11-13 2010-09-23 Medtronic Minimed Inc LONG-TERM ARRANGEMENT ANALYTENSENSOR
US8414489B2 (en) 2003-11-13 2013-04-09 Medtronic Minimed, Inc. Fabrication of multi-sensor arrays
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2005057168A2 (en) 2003-12-05 2005-06-23 Dexcom, Inc. Calibration techniques for a continuous analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US6946728B2 (en) * 2004-02-19 2005-09-20 Hewlett-Packard Development Company, L.P. System and methods for hermetic sealing of post media-filled MEMS package
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc Method and apparatus for a fluid sampling device
WO2005122959A2 (en) 2004-06-08 2005-12-29 Advanced Stent Technologies, Inc. Stent with protruding branch portion for bifurcated vessels
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US20060270922A1 (en) 2004-07-13 2006-11-30 Brauker James H Analyte sensor
US20070036835A1 (en) * 2004-07-19 2007-02-15 Microchips, Inc. Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents
WO2006015299A2 (en) 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
US7604628B2 (en) * 2004-09-01 2009-10-20 Microchips, Inc. Multi-cap reservoir devices for controlled release or exposure of reservoir contents
US20060076634A1 (en) * 2004-09-27 2006-04-13 Lauren Palmateer Method and system for packaging MEMS devices with incorporated getter
EP1812090A1 (en) * 2004-10-28 2007-08-01 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
KR101211576B1 (en) 2004-11-04 2012-12-12 마이크로칩스 인코포레이티드 Compression and cold weld sealing methods and devices
US7413846B2 (en) * 2004-11-15 2008-08-19 Microchips, Inc. Fabrication methods and structures for micro-reservoir devices
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
EP1843783B1 (en) * 2005-01-25 2012-05-30 MicroCHIPS, Inc. Control of drug release by transient modification of local microenvironments
US9095722B2 (en) * 2005-02-01 2015-08-04 Second Sight Medical Products, Inc. Micro-miniature implantable coated device
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
EP1893080A2 (en) 2005-06-21 2008-03-05 CardioMems, Inc. Method of manufacturing implantable wireless sensor for in vivo pressure measurement
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
WO2007047556A2 (en) * 2005-10-14 2007-04-26 Microchips, Inc. Passive wear-indicating sensor for implantable prosthetic device
US7540881B2 (en) 2005-12-22 2009-06-02 Boston Scientific Scimed, Inc. Bifurcation stent pattern
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US8642059B2 (en) 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
EP2043728A2 (en) * 2006-07-11 2009-04-08 Microchips, Inc. Multi-reservoir pump device for dialysis, biosensing, or delivery of substances
DE102006035197B4 (en) * 2006-07-29 2016-09-29 Bayerische Motoren Werke Aktiengesellschaft Device housing and set of device housings
EP1892877B1 (en) * 2006-08-25 2008-12-03 Alcatel Lucent Digital signal receiver with Q-monitor
US7951191B2 (en) 2006-10-10 2011-05-31 Boston Scientific Scimed, Inc. Bifurcated stent with entire circumferential petal
US7842082B2 (en) 2006-11-16 2010-11-30 Boston Scientific Scimed, Inc. Bifurcated stent
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8649840B2 (en) * 2007-06-07 2014-02-11 Microchips, Inc. Electrochemical biosensors and arrays
US20080306444A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US7959669B2 (en) 2007-09-12 2011-06-14 Boston Scientific Scimed, Inc. Bifurcated stent with open ended side branch support
US8974809B2 (en) * 2007-09-24 2015-03-10 Boston Scientific Scimed, Inc. Medical devices having a filter insert for controlled diffusion
EP2227132B1 (en) 2007-10-09 2023-03-08 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
US7833266B2 (en) 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
US8277501B2 (en) 2007-12-21 2012-10-02 Boston Scientific Scimed, Inc. Bi-stable bifurcated stent petal geometry
US7869044B2 (en) * 2008-01-16 2011-01-11 Optotrace Technologies, Inc. Optical sensing system based on a micro-array structure
US8521273B2 (en) 2008-01-29 2013-08-27 Gilbert H. KLIMAN Drug delivery devices, kits and methods therefor
EP3387993A3 (en) * 2008-03-28 2018-11-14 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8182442B2 (en) * 2008-04-09 2012-05-22 Electrocore Llc Pyloric valve devices and methods
EP2265324B1 (en) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integrated analyte measurement system
US20090270795A1 (en) * 2008-04-23 2009-10-29 Medtronic, Inc. Method for welding a barrier in an implantable drug delivery device
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US8560039B2 (en) 2008-09-19 2013-10-15 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
US7838715B2 (en) * 2009-01-21 2010-11-23 Palo Alto Research Center Incorporated Drug deactivation system and method of deactivating a drug using the same
US9480795B2 (en) * 2009-01-21 2016-11-01 Palo Alto Research Center Incorporated Sensor system for drug delivery device, drug delivery device having the same and method of using the same
US8236238B2 (en) 2009-01-21 2012-08-07 Palo Alto Research Center Incorporated Drug deactivation system
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
FR2945097B1 (en) * 2009-04-30 2011-06-03 Commissariat Energie Atomique MICROFLUIDIC VALVE FOR SINGLE USE.
WO2011018407A1 (en) * 2009-08-08 2011-02-17 Sanofi-Aventis Deutschland Gmbh Implantable sensor device and medical delivery device connectable to such a sensor device
WO2011047271A1 (en) 2009-10-16 2011-04-21 Microchips, Inc. Multi-channel potentiostat for biosensor arrays
US20110139484A1 (en) * 2009-12-15 2011-06-16 Advanced Bionics, Llc Hermetic Electrical Feedthrough
AU2011213616B2 (en) 2010-02-08 2013-08-15 Microchips, Inc. Low-permeability, laser-activated drug delivery device
US8828246B2 (en) 2010-02-18 2014-09-09 Anpac Bio-Medical Science Co., Ltd. Method of fabricating micro-devices
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
DE102010015813A1 (en) * 2010-04-20 2011-10-20 Krohne Messtechnik Gmbh Sensor arrangement for a calorimetric mass flowmeter
CN102834347B (en) * 2010-04-23 2015-12-02 埃普科斯股份有限公司 There is MEMS and the manufacture method of film
US8386047B2 (en) 2010-07-15 2013-02-26 Advanced Bionics Implantable hermetic feedthrough
US8552311B2 (en) 2010-07-15 2013-10-08 Advanced Bionics Electrical feedthrough assembly
WO2012106326A1 (en) * 2011-01-31 2012-08-09 The Regents Of The University Of California Using millisecond pulsed laser welding in mems packaging
DK2673020T3 (en) 2011-02-09 2017-11-20 Sanofi Aventis Deutschland PEN INJECTION DEVICE FOR TWO PHARMACEUTICALS WITH MICROR RESERVES CONTAINING SECONDARY EMERGENCY MEDICINE
EP2741720A1 (en) * 2011-08-10 2014-06-18 On Demand Therapeutics, Inc. Laser-activated drug delivery device
EP2747642B1 (en) * 2011-08-25 2021-04-28 Microchips Biotech, Inc. Space-efficient containment devices and method of making same
US10427153B2 (en) 2011-08-25 2019-10-01 Microchips Biotech, Inc. Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid
WO2013029177A1 (en) * 2011-08-29 2013-03-07 Sciense Systems Inc. Monolithic package for housing microelectromechanical systems
US9314571B1 (en) 2012-02-10 2016-04-19 Mphase Technologies, Inc. Drug delivery system
US9500808B2 (en) * 2012-05-09 2016-11-22 The Boeing Company Ruggedized photonic crystal sensor packaging
EP2934289B1 (en) 2012-12-21 2018-04-25 Microchips Biotech, Inc. Implantable medical device for minimally-invasive insertion
US9620473B1 (en) 2013-01-18 2017-04-11 University Of Notre Dame Du Lac Quilt packaging system with interdigitated interconnecting nodules for inter-chip alignment
MY175542A (en) 2013-02-28 2020-07-01 Microchips Biotech Inc Implantable medical device for minimally-invasive insertion
JP6578562B2 (en) * 2013-04-12 2019-09-25 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ Inorganic and organic transient electronic devices
US9437756B2 (en) 2013-09-27 2016-09-06 Sunpower Corporation Metallization of solar cells using metal foils
US10629969B2 (en) 2014-07-27 2020-04-21 Sonova Ag Batteries and battery manufacturing methods
CN107148644B (en) * 2014-10-30 2020-04-03 富士胶片株式会社 Sensor device and sensor system
US11268927B2 (en) 2016-08-30 2022-03-08 Analog Devices International Unlimited Company Electrochemical sensor, and a method of forming an electrochemical sensor
US10620151B2 (en) 2016-08-30 2020-04-14 Analog Devices Global Electrochemical sensor, and a method of forming an electrochemical sensor
US10056310B2 (en) 2016-09-26 2018-08-21 International Business Machines Corporation Electrolytic seal
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
AU2018354120A1 (en) 2017-10-24 2020-04-23 Dexcom, Inc. Pre-connected analyte sensors
KR20200100112A (en) 2017-12-19 2020-08-25 더 유니버시티 오브 브리티쉬 콜롬비아 Layered structure and method of manufacturing the same
US11022579B2 (en) 2018-02-05 2021-06-01 Analog Devices International Unlimited Company Retaining cap
CN108358160B (en) * 2018-04-18 2023-08-01 中国兵器工业集团第二一四研究所苏州研发中心 Hoisting type MEMS device packaging structure capable of releasing stress
DE102020119220A1 (en) 2020-07-21 2022-01-27 Plasmatreat Gmbh Process for manufacturing a pressure-welded component

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0347579A2 (en) * 1988-06-01 1989-12-27 Daimler-Benz Aerospace Aktiengesellschaft Device having a specific support structure for receiving, analysing and treating samples
US5574313A (en) * 1994-10-17 1996-11-12 Litten Systems, Inc. Hermetically sealed microwave integrated circuit package with ground plane fused to package frame
WO1998000107A2 (en) * 1996-07-02 1998-01-08 Massachusetts Institute Of Technology Microchip drug delivery devices
US6062461A (en) * 1998-06-03 2000-05-16 Delphi Technologies, Inc. Process for bonding micromachined wafers using solder

Family Cites Families (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146029A (en) 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
US4089734A (en) 1974-09-16 1978-05-16 Raytheon Company Integrated circuit fusing technique
US4209894A (en) 1978-04-27 1980-07-01 Texas Instruments Incorporated Fusible-link semiconductor memory
US4345981A (en) 1978-11-24 1982-08-24 Diamond Shamrock Corporation Anodically polarized surface for biofouling and scale control
US4360019A (en) 1979-02-28 1982-11-23 Andros Incorporated Implantable infusion device
US4731051A (en) 1979-04-27 1988-03-15 The Johns Hopkins University Programmable control means for providing safe and controlled medication infusion
JPS57163309A (en) 1981-04-01 1982-10-07 Olympus Optical Co Ltd Capsule apparatus for medical use
US4659696A (en) 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
US4856188A (en) 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
GB8422876D0 (en) 1984-09-11 1984-10-17 Secr Defence Silicon implant devices
US4585652A (en) 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US4734300A (en) 1986-03-14 1988-03-29 Hughes Aircraft Company Methods for removing parylene coatings from predetermined, desired areas of a substrate
US4731049A (en) 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
NZ228285A (en) 1988-03-11 1991-08-27 Teikoku Seiyaku Kk Pharmaceutical composition comprising a polypeptide and adapted for intravaginal administration
US5387419A (en) 1988-03-31 1995-02-07 The University Of Michigan System for controlled release of antiarrhythmic agents
US5252294A (en) 1988-06-01 1993-10-12 Messerschmitt-Bolkow-Blohm Gmbh Micromechanical structure
WO1990002546A1 (en) 1988-09-09 1990-03-22 The Ronald T. Dodge Company Pharmaceuticals microencapsulated by vapor deposited polymers and method
US5200051A (en) 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US4994023A (en) 1989-08-08 1991-02-19 Wellinghoff Stephen T Electrochemical drug release and article
US5041107A (en) 1989-10-06 1991-08-20 Cardiac Pacemakers, Inc. Electrically controllable, non-occluding, body implantable drug delivery system
US5229131A (en) 1990-02-05 1993-07-20 University Of Michigan Pulsatile drug delivery system
US5147297A (en) 1990-05-07 1992-09-15 Alza Corporation Iontophoretic delivery device
US5170801A (en) 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US5167625A (en) 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5196002A (en) 1990-10-09 1993-03-23 University Of Utah Research Foundation Implantable drug delivery system with piston acutation
US5391164A (en) 1991-05-03 1995-02-21 Giampapa; Vincent C. Subcutaneous implantable multiple-agent delivery system
US5279607A (en) 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
US5524338A (en) 1991-10-22 1996-06-11 Pi Medical Corporation Method of making implantable microelectrode
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
AU664214B2 (en) 1991-11-13 1995-11-09 Elan Corporation, Plc Drug delivery device
US5193539A (en) 1991-12-18 1993-03-16 Alfred E. Mann Foundation For Scientific Research Implantable microstimulator
US5262127A (en) 1992-02-12 1993-11-16 The Regents Of The University Of Michigan Solid state chemical micro-reservoirs
US5429822A (en) 1992-03-13 1995-07-04 Cambridge Scientific, Inc. Biodegradable bursting release system
US5756117A (en) 1992-04-08 1998-05-26 International Medical Asscociates, Inc. Multidose transdermal drug delivery system
US5304293A (en) 1992-05-11 1994-04-19 Teknekron Sensor Development Corporation Microsensors for gaseous and vaporous species
US5318557A (en) 1992-07-13 1994-06-07 Elan Medical Technologies Limited Medication administering device
US5368588A (en) 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
US5366454A (en) 1993-03-17 1994-11-22 La Corporation De L'ecole Polytechnique Implantable medication dispensing device
US5427585A (en) 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
US5474527A (en) 1993-03-29 1995-12-12 Bettinger; David S. Positive displacement transdermal system
US5368704A (en) 1993-08-06 1994-11-29 Teknekron Corporation Micro-electrochemical valves and method
US5900160A (en) 1993-10-04 1999-05-04 President And Fellows Of Harvard College Methods of etching articles via microcontact printing
US5490962A (en) 1993-10-18 1996-02-13 Massachusetts Institute Of Technology Preparation of medical devices by solid free-form fabrication methods
ES2325393T3 (en) 1993-10-28 2009-09-03 Houston Advanced Research Center POROUS FLOW EQUIPMENT THROUGH MICROFABRICATED FOR THE DIFFERENTIATED DETECTION OF UNION REACTIONS.
US5770076A (en) 1994-03-07 1998-06-23 The Regents Of The University Of California Micromachined capsules having porous membranes and bulk supports
US5893974A (en) 1994-03-07 1999-04-13 Regents Of University Of California Microfabricated capsules for immunological isolation of cell transplants
US5798042A (en) 1994-03-07 1998-08-25 Regents Of The University Of California Microfabricated filter with specially constructed channel walls, and containment well and capsule constructed with such filters
US5985328A (en) 1994-03-07 1999-11-16 Regents Of The University Of California Micromachined porous membranes with bulk support
US5660680A (en) 1994-03-07 1997-08-26 The Regents Of The University Of California Method for fabrication of high vertical aspect ratio thin film structures
US5651900A (en) 1994-03-07 1997-07-29 The Regents Of The University Of California Microfabricated particle filter
US5510138A (en) 1994-05-24 1996-04-23 Delco Electronics Corporation Hot melt conformal coating materials
US5782891A (en) * 1994-06-16 1998-07-21 Medtronic, Inc. Implantable ceramic enclosure for pacing, neurological, and other medical applications in the human body
US5837276A (en) 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US6063116A (en) 1994-10-26 2000-05-16 Medarex, Inc. Modulation of cell proliferation and wound healing
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5562715A (en) 1994-12-01 1996-10-08 Czura; John J. Cardiac pulse generator
US5591217A (en) 1995-01-04 1997-01-07 Plexus, Inc. Implantable stimulator with replenishable, high value capacitive power source and method therefor
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
AU716005B2 (en) 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
US5992769A (en) 1995-06-09 1999-11-30 The Regents Of The University Of Michigan Microchannel system for fluid delivery
US5713954A (en) 1995-06-13 1998-02-03 Abiomed R&D, Inc. Extra cardiac ventricular assist device
SE9502258D0 (en) 1995-06-21 1995-06-21 Pharmacia Biotech Ab Method for the manufacture of a membrane-containing microstructure
US5872010A (en) 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
US6066163A (en) 1996-02-02 2000-05-23 John; Michael Sasha Adaptive brain stimulation method and system
US6261584B1 (en) 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
DE19610293C1 (en) 1996-03-15 1997-07-31 Fraunhofer Ges Forschung Electronically-breakable microencapsulation system for sensitive materials
US5824204A (en) 1996-06-27 1998-10-20 Ic Sensors, Inc. Micromachined capillary electrophoresis device
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US6136212A (en) 1996-08-12 2000-10-24 The Regents Of The University Of Michigan Polymer-based micromachining for microfluidic devices
IN184589B (en) 1996-10-16 2000-09-09 Alza Corp
US6376477B2 (en) 1996-11-25 2002-04-23 Merck & Co., Inc. Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism
US5945412A (en) 1996-12-09 1999-08-31 Merck & Co., Inc. Methods and compositions for preventing and treating bone loss
US5782799A (en) 1997-02-07 1998-07-21 Sarcos, Inc. Method for automatic dosing of drugs
US7575770B2 (en) * 1997-03-13 2009-08-18 Safefresh Technologies, Llc Continuous production and packaging of perishable goods in low oxygen environments
US5938923A (en) 1997-04-15 1999-08-17 The Regents Of The University Of California Microfabricated filter and capsule using a substrate sandwich
AU727083B2 (en) 1997-04-25 2000-11-30 Caliper Life Sciences, Inc. Microfluidic devices incorporating improved channel geometries
US5976336A (en) 1997-04-25 1999-11-02 Caliper Technologies Corp. Microfluidic devices incorporating improved channel geometries
US5869004A (en) 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems
SE9702401D0 (en) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
IL121286A0 (en) 1997-07-11 1998-01-04 Pets N People Ltd Apparatus and methods for dispensing pet care substances
US5961492A (en) * 1997-08-27 1999-10-05 Science Incorporated Fluid delivery device with temperature controlled energy source
US5972027A (en) 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
CA2306344A1 (en) * 1997-10-14 1999-04-22 Masahiko Sato Method of building and maintaining bone
US5925069A (en) 1997-11-07 1999-07-20 Sulzer Intermedics Inc. Method for preparing a high definition window in a conformally coated medical device
US5948227A (en) 1997-12-17 1999-09-07 Caliper Technologies Corp. Methods and systems for performing electrophoretic molecular separations
US6140740A (en) 1997-12-30 2000-10-31 Remon Medical Technologies, Ltd. Piezoelectric transducer
US6001090A (en) 1998-02-09 1999-12-14 Lenhart; Douglas Thermal pharmaceutical delivery system
US7208010B2 (en) * 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6027695A (en) 1998-04-01 2000-02-22 Dupont Pharmaceuticals Company Apparatus for holding small volumes of liquids
US6243608B1 (en) 1998-06-12 2001-06-05 Intermedics Inc. Implantable device with optical telemetry
US6232150B1 (en) 1998-12-03 2001-05-15 The Regents Of The University Of Michigan Process for making microstructures and microstructures made thereby
US6288888B1 (en) 1998-12-25 2001-09-11 Nec Corporation Electric double layer capacitor
US6171850B1 (en) 1999-03-08 2001-01-09 Caliper Technologies Corp. Integrated devices and systems for performing temperature controlled reactions and analyses
US6096656A (en) 1999-06-24 2000-08-01 Sandia Corporation Formation of microchannels from low-temperature plasma-deposited silicon oxynitride
US6334859B1 (en) 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
CA2381951A1 (en) * 1999-08-18 2001-02-22 Microchips, Inc. Thermally-activated microchip chemical delivery devices
EP1229901B1 (en) * 1999-11-17 2009-03-18 Boston Scientific Limited Microfabricated devices for the delivery of molecules into a carrier fluid
DE60027458T2 (en) 1999-12-10 2007-07-05 Massachusetts Institute Of Technology, Cambridge MICROCHIP DRUG DISABLING SYSTEMS AND MANUFACTURING METHOD
US6328699B1 (en) 2000-01-11 2001-12-11 Cedars-Sinai Medical Center Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure
WO2001064344A2 (en) * 2000-03-02 2001-09-07 Microchips, Inc. Microfabricated devices for the storage and selective exposure of chemicals and devices
US6730072B2 (en) * 2000-05-30 2004-05-04 Massachusetts Institute Of Technology Methods and devices for sealing microchip reservoir devices
AU2001283358A1 (en) * 2000-08-14 2002-02-25 Pharmacia Corporation Drug delivery system with burst electrode
US6437640B1 (en) * 2000-09-12 2002-08-20 The Aerospace Corporation Addressable diode isolated thin film array
US6403403B1 (en) * 2000-09-12 2002-06-11 The Aerospace Corporation Diode isolated thin film fuel cell array addressing method
US6490751B2 (en) * 2000-09-15 2002-12-10 William Ganzenmuller Vehicle vacuum system
ATE314822T1 (en) 2000-10-10 2006-02-15 Microchips Inc MICROCHIP RESERVOIR DEVICES WITH WIRELESS TRANSMISSION OF ENERGY AND DATA
AU2002224453A1 (en) 2000-10-11 2002-04-22 Microchips, Inc. Microchip reservoir devices and facilitated corrosion of electrodes
US6378292B1 (en) * 2000-11-10 2002-04-30 Honeywell International Inc. MEMS microthruster array
DE10061057A1 (en) * 2000-12-08 2002-06-13 Pharmed Holding Gmbh Chip systems for the controlled emission of chemically sensitive substances
US6666821B2 (en) * 2001-01-08 2003-12-23 Medtronic, Inc. Sensor system
ATE359762T1 (en) 2001-01-09 2007-05-15 Microchips Inc FLEXIBLE MICROCHIP DEVICES FOR OPHTHALMOLOGICAL AND OTHER APPLICATIONS
US6571125B2 (en) * 2001-02-12 2003-05-27 Medtronic, Inc. Drug delivery device
US7338522B2 (en) * 2001-02-13 2008-03-04 Second Sight Medical Products, Inc. Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress
US6858220B2 (en) 2001-02-28 2005-02-22 Second Sight Medical Products, Inc. Implantable microfluidic delivery system using ultra-nanocrystalline diamond coating
EP1387671A1 (en) * 2001-05-03 2004-02-11 MASSACHUSETTS EYE & EAR INFIRMARY Implantable drug delivery device and use thereof
WO2002096389A1 (en) * 2001-05-30 2002-12-05 Microchips, Inc. Conformal coated microchip reservoir devices
ATE285756T1 (en) * 2001-06-28 2005-01-15 Microchips Inc METHOD FOR HERMETIC SEALING MICROCHIP RESERVOIR DEVICES
WO2003048665A1 (en) * 2001-12-03 2003-06-12 Massachusetts Institute Of Technology Microscale lyophilization and drying methods for the stabilization of molecules
US6893885B2 (en) 2002-01-18 2005-05-17 The Regents Of The University Of Michigan Method for electrically and mechanically connecting microstructures using solder
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
WO2004026281A2 (en) * 2002-09-23 2004-04-01 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
WO2004033036A2 (en) * 2002-10-04 2004-04-22 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0347579A2 (en) * 1988-06-01 1989-12-27 Daimler-Benz Aerospace Aktiengesellschaft Device having a specific support structure for receiving, analysing and treating samples
US5574313A (en) * 1994-10-17 1996-11-12 Litten Systems, Inc. Hermetically sealed microwave integrated circuit package with ground plane fused to package frame
WO1998000107A2 (en) * 1996-07-02 1998-01-08 Massachusetts Institute Of Technology Microchip drug delivery devices
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US6062461A (en) * 1998-06-03 2000-05-16 Delphi Technologies, Inc. Process for bonding micromachined wafers using solder

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