WO2002078785A3 - A brachytherapy device and method of use - Google Patents

A brachytherapy device and method of use Download PDF

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Publication number
WO2002078785A3
WO2002078785A3 PCT/US2002/009873 US0209873W WO02078785A3 WO 2002078785 A3 WO2002078785 A3 WO 2002078785A3 US 0209873 W US0209873 W US 0209873W WO 02078785 A3 WO02078785 A3 WO 02078785A3
Authority
WO
WIPO (PCT)
Prior art keywords
disclosed
methods
devices
coating layer
brachytherapy
Prior art date
Application number
PCT/US2002/009873
Other languages
French (fr)
Other versions
WO2002078785A9 (en
WO2002078785A2 (en
Inventor
Neal A Scott
Janet M Hampikian
Original Assignee
Radiovascular Inc
Neal A Scott
Janet M Hampikian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radiovascular Inc, Neal A Scott, Janet M Hampikian filed Critical Radiovascular Inc
Priority to AU2002309523A priority Critical patent/AU2002309523A1/en
Publication of WO2002078785A2 publication Critical patent/WO2002078785A2/en
Publication of WO2002078785A9 publication Critical patent/WO2002078785A9/en
Publication of WO2002078785A3 publication Critical patent/WO2002078785A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A61N5/1015—Treatment of resected cavities created by surgery, e.g. lumpectomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007—Arrangements or means for the introduction of sources into the body
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C18/00—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating
    • C23C18/02—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by thermal decomposition
    • C23C18/12—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material
    • C23C18/1204—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material inorganic material, e.g. non-oxide and non-metallic such as sulfides, nitrides based compounds
    • C23C18/1208—Oxides, e.g. ceramics
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C18/00—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating
    • C23C18/02—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by thermal decomposition
    • C23C18/12—Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material
    • C23C18/125—Process of deposition of the inorganic material
    • C23C18/1254—Sol or sol-gel processing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002—Intraluminal radiation therapy
    • A61N2005/1005—Intraluminal radiation therapy with asymmetrical radiation pattern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007—Arrangements or means for the introduction of sources into the body
    • A61N2005/1012—Templates or grids for guiding the introduction of sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A61N2005/1018—Intracavitary radiation therapy with multiple channels for guiding radioactive sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019—Sources therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1027—Interstitial radiation therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/12—All metal or with adjacent metals
    • Y10T428/12493—Composite; i.e., plural, adjacent, spatially distinct metal components [e.g., layers, joint, etc.]
    • Y10T428/12771—Transition metal-base component
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/12—All metal or with adjacent metals
    • Y10T428/12493—Composite; i.e., plural, adjacent, spatially distinct metal components [e.g., layers, joint, etc.]
    • Y10T428/12771—Transition metal-base component
    • Y10T428/12861—Group VIII or IB metal-base component
    • Y10T428/12944—Ni-base component
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/12—All metal or with adjacent metals
    • Y10T428/12493—Composite; i.e., plural, adjacent, spatially distinct metal components [e.g., layers, joint, etc.]
    • Y10T428/12986—Adjacent functionally defined components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31678—Of metal

Abstract

The present invention is directed to a brachytherapy device comprising a substrate comprising at least one radioactive coating layer formed thereon. The radioactive coating layer has a total radioactivity that varies in at least one dimension of the device. Methods of making radioactive coatings, such as electrochemical deposition, electroless deposition and sol-gel are also disclosed. Suitable substrates include medical devices, such as catheters, stents, brachytherapy devices and guidewires, or components thereof. The disclosed methods produce medical devices capable of generating asymmetric, or targeted, radiation fields that correspond to the morphology of a tumor. Methods of using these devices to treat cancer of the breast, brain, prostate, uterine, head and neck are also disclosed.
PCT/US2002/009873 2001-04-02 2002-04-02 A brachytherapy device and method of use WO2002078785A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002309523A AU2002309523A1 (en) 2001-04-02 2002-04-02 A brachytherapy device and method of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28013601P 2001-04-02 2001-04-02
US60/280,136 2001-04-02

Publications (3)

Publication Number Publication Date
WO2002078785A2 WO2002078785A2 (en) 2002-10-10
WO2002078785A9 WO2002078785A9 (en) 2002-12-27
WO2002078785A3 true WO2002078785A3 (en) 2003-05-01

Family

ID=23071826

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/009873 WO2002078785A2 (en) 2001-04-02 2002-04-02 A brachytherapy device and method of use

Country Status (3)

Country Link
US (1) US20030092957A1 (en)
AU (1) AU2002309523A1 (en)
WO (1) WO2002078785A2 (en)

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WO2006053312A1 (en) * 1995-06-07 2006-05-18 Kyphon Inc. System and method for delivering a therapeutic agent for bone disease
US7776379B2 (en) 2001-09-19 2010-08-17 Medlogics Device Corporation Metallic structures incorporating bioactive materials and methods for creating the same
DE60324448D1 (en) 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy
US7208172B2 (en) 2003-11-03 2007-04-24 Medlogics Device Corporation Metallic composite coating for delivery of therapeutic agents from the surface of implantable devices
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
EP1681077A1 (en) * 2005-01-12 2006-07-19 Acrostak Corp. A positioning device and a procedure for treating the walls of a resection cavity
CN101282760A (en) 2005-08-11 2008-10-08 纳沃特克医药有限公司 Medical treatment system and method using radioactivity based position sensor
BRPI0616514A2 (en) 2005-08-11 2011-06-21 Navotek Medical Ltd medical treatment system and method using position sensor based radioactivity
WO2007053823A2 (en) 2005-10-31 2007-05-10 Biolucent, Inc. Brachytherapy apparatus and methods of using same
US7862496B2 (en) 2005-11-10 2011-01-04 Cianna Medical, Inc. Brachytherapy apparatus and methods for using them
US7887476B2 (en) 2005-11-10 2011-02-15 Cianna Medical, Inc. Helical brachytherapy apparatus and methods of using same
US20070270627A1 (en) * 2005-12-16 2007-11-22 North American Scientific Brachytherapy apparatus for asymmetrical body cavities
US8137256B2 (en) * 2005-12-16 2012-03-20 Portola Medical, Inc. Brachytherapy apparatus
US20090312593A1 (en) * 2006-03-14 2009-12-17 Drobnik Christopher D Radioactive Device for treatment of a Tumor
US9072893B2 (en) 2006-06-02 2015-07-07 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US20080097139A1 (en) * 2006-07-14 2008-04-24 Boston Scientific Scimed, Inc. Systems and methods for treating lung tissue
US7686756B2 (en) * 2006-08-29 2010-03-30 Ciratech Oncology Brachytherapy devices and related methods and computer program products
AU2007307854B2 (en) 2006-10-08 2012-01-19 Cianna Medical, Inc. Expandable brachytherapy apparatus
WO2008058089A2 (en) * 2006-11-03 2008-05-15 North American Scientific, Inc. Brachytherapy device having seed tubes with individually-settable tissue spacings
US8517907B2 (en) 2007-12-16 2013-08-27 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US20090216065A1 (en) 2008-02-22 2009-08-27 C. R. Bard, Inc. Radiation Containing Seeds and Method for High Visibility Magnetic Imaging
EP2296756A1 (en) 2008-06-04 2011-03-23 Neovista, Inc. Handheld radiation delivery system for advancing a radiation source wire
US8636635B2 (en) 2008-08-18 2014-01-28 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US8814775B2 (en) 2010-03-18 2014-08-26 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US9883919B2 (en) 2010-07-21 2018-02-06 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US9067063B2 (en) 2010-11-03 2015-06-30 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
CA2838017C (en) 2011-06-03 2019-08-27 DePuy Synthes Products, LLC Multilayered valve metal coating for a surgical implant
CN104303184B (en) * 2012-03-21 2018-05-15 皇家飞利浦有限公司 Integrate the Clinical workstations of imaging of medical and biopsy data and use its method
RU2763750C2 (en) 2017-05-11 2022-01-10 Альфа Тау Медикал Лтд. Polymer coatings for brachytherapy devices
US10485632B1 (en) 2018-11-27 2019-11-26 King Saud University Intraoral attachment clip for attachment of objects to edentulous ridges
CN110438536A (en) * 2019-07-30 2019-11-12 华东师范大学 A kind of electro-deposition-auto-deposition prepares αsource experimental provision and its experimental method
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Also Published As

Publication number Publication date
WO2002078785A9 (en) 2002-12-27
AU2002309523A1 (en) 2002-10-15
US20030092957A1 (en) 2003-05-15
WO2002078785A2 (en) 2002-10-10

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